bioRxiv directory

Molitor, L.; Krispin, S.; Van-Zuiden, W.; Danino, Y. M.; Rudberg, N.; Bar, C.; Amzallag, E.; Lubliner, J.; Siany, A.; Eitan, C.; Cohen, Y.; Yacovzada, N. S.; Hornstein, E.

10.1101/2024.01.31.572110 — systems biology — Posted on 2024-01-31

10 Replicating enzymatic activity by positioning active sites with synthetic protein scaffolds

Ding, Y.; Zhang, S.; Hess, H.; Kong, X.; Zhang, Y.

10.1101/2024.01.31.577620 — biochemistry — Posted on 2024-01-31

11 Global genomic diversity of Pseudomonas aeruginosa in bronchiectasis

Harrington, N. E.; Kottara, A.; Cagney, K.; Shepherd, M. J.; Grimsey, E. M.; Fu, T.; Hull, R. C.; Childs, D. Z.; Fothergill, J. L.; Chalmers, J. D.; Brockhurst, M. A.; Paterson, S.

10.1101/2024.01.30.577916 — genomics — Posted on 2024-01-31

12 Outcrossing increases resistance against coevolving parasites

Slowinski, S. P.; Gresham, J. D.; Penley, M. J.; Lively, C. M.; Morran, L.

10.1101/2024.01.30.578011 — evolutionary biology — Posted on 2024-01-31

13 Bacterial communities of Cassiopea in the Florida Keys share major bacterial taxa with coral microbiomes

Muffett, K. M.; Miglietta, M. P.; Labonte, J.

10.1101/2024.01.30.577655 — ecology — Posted on 2024-01-31

14 The collective application of shorebird tracking data to conservation

Harrison, A.-L.; Stenzel, C.; Anderson, A.; Howell, J.; Lanctot, R. B.; Aikens, M.; Aldabe, J.; Berigan, L. A.; Bety, J.; Blomberg, E.; Bosi de Almeida, J.; Boyce, A. J.; Bradley, D. W.; Brown, S.; Carlisle, J.; Cheskey, E.; Christie, K.; Christin, S.; Clay, R.; Dayer, A.; Deppe, J. L.; English, W.; Flemming, S. A.; Gilg, O.; Gilroy, C.; Heath, S.; Hill, J. M.; Hipfner, J. M.; Johnson, J. A.; Johnson, L.; Kempenaers, B.; Knaga, P.; Kwon, E.; Lagasse, B. J.; Lamarre, J.-F.; Latty, C.; Leandri-Breton, D.-J.; Lecomte, N.; Loring, P.; McGuire, R.; Moorhead, S.; Navedo, J. G.; Newstead, D.; Nol, E.

10.1101/2024.01.30.576574 — ecology — Posted on 2024-01-31

15 Community context influences the conjugation efficiency of E. coli

Bustamante, M.; Koopman, F.; Martens, J.; Brons, J. K.; DelaFuente, J.; Kuipers, O.; van Doorn, G. S.; de Vos, M.

10.1101/2024.01.30.577951 — ecology — Posted on 2024-01-31

16 Longitudinal fluctuations in protein concentrations and higher-order structures in the plasma proteome of kidney failure patients subjected to a kidney transplant

Nteak, S. K.; Voellmy, F.; Lukassen, M. V.; van den Toorn, H.; den Boer, M. A.; Bondt, A.; van der Lans, S. P. A.; Haas, P.-J.; van Zuilen, A. D.; Rooijakkers, S. H. M.; Heck, A. J. R.

10.1101/2024.01.31.578168 — molecular biology — Posted on 2024-01-31

17 OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Sepulveda, H.; Li, X.; Yue, X.; Angel, J. C.; Arteaga-Vazquez, L. J.; Brown, C.; Brunelli, M.; Jansz, N.; Puddu, F.; Scotcher, J.; Creed, P.; Kennedy, P. H.; Manriquez, C.; Myers, S. A.; Crawford, R.; Faulkner, G. J.; Rao, A.

10.1101/2024.01.31.578097 — molecular biology — Posted on 2024-01-31

18 Minor changes in electrostatics robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles

Motsa, B. B.; Sharma, T.; Chapagain, P. P.; Stahelin, R. V.

10.1101/2024.01.30.578092 — microbiology — Posted on 2024-01-31

19 Surface versus volume synthesis governs growth-dependent efficacy of a β-lactam antibiotic

Brouwers, R.; Mancini, L.; Tavaddod, S.; Biboy, J.; Mauri, M.; Tatham, E.; Enghardt, M.-L.; Zander, A.; Cicuta, P.; Vollmer, W.; Allen, R.

10.1101/2024.01.31.578235 — microbiology — Posted on 2024-01-31

20 SingleM and Sandpiper: Robust microbial taxonomic profiles from metagenomic data

Woodcroft, B. J.; Aroney, S. T. N.; Zhao, R.; Cunningham, M.; Mitchell, J. A. M.; Blackall, L.; Tyson, G. W.

10.1101/2024.01.30.578060 — microbiology — Posted on 2024-01-31

21 Identification, antimicrobial resistance and molecular detection of Shiga toxin-producing E. coli (STEC) isolated from raw milk of cattle in Chitwan, Nepal

Shrestha, S.; Basnet, H. B.; Luitel, H.; Bastola, S.; Bhattarai, R. K.

10.1101/2024.01.30.578021 — microbiology — Posted on 2024-01-31

22 Variation of carbon, nitrogen and phosphorus content in fungi reflects their ecology and phylogeny

Panek, M.; Vlkova, T.; Michalova, T.; Borovicka, J.; Tedersoo, L.; Adamczyk, B.; Baldrian, P.; Lopez-Mondejar, R.

10.1101/2024.01.31.578150 — microbiology — Posted on 2024-01-31

23 Critical concentration of formate governs the expression of the flagellar and the pathogenicity island-1 genes in Salmonella Typhimurium

MUKHERJEE, D.; Chakravortty, D.

10.1101/2024.01.30.577997 — microbiology — Posted on 2024-01-31

24 KSHV genome harbors both constitutive and lytically induced enhancers

Roy Chowdhury, N.; Gurevich, V.; Shamay, M.

10.1101/2024.01.30.577957 — microbiology — Posted on 2024-01-31

25 Metapopulation model of phage therapy of an acute Pseudomonas aeruginosa lung infection

Rodriguez-Gonzalez, R. A.; Balacheff, Q.; Debarbieux, L.; Marchi, J.; Weitz, J. S.

10.1101/2024.01.31.578251 — microbiology — Posted on 2024-01-31

26 A novel microporous biomaterial vaccine platform for long-lasting antibody mediated immunity against viral infection.

Mayer, D. P.; Nelson, M.; Andriyanova, D.; Antao, O. Q.; Chen, J. S.; Scumpia, P. O.; Weaver, W. M.; Deshayes, S.; Weinstein, J. S.

10.1101/2024.01.30.578038 — immunology — Posted on 2024-01-31

27 Virus-associated Inflammation Imprints an Inflammatory Profile on Long-lived Monocyte-derived Macrophages in the Human Liver

Sanchez, J.-D.; Nkongolo, S.; Traum, D.; Kim, S. C.; Mahamed, D.; Mehrotra, A.; Patel, A.; Chen, D.; Fung, S.; Gaggar, A.; Feld, J. J.; Chang, K.-M.; Wallin, J. J.; Janssen, H. L. A.; Gehring, A. J.

10.1101/2024.01.31.578178 — immunology — Posted on 2024-01-31

28 A constraint-based framework to reconstruct interaction networks in microbial communities

Oftadeh, O.; Sahin, A.; Vayena, E.; Hatzimanikatis, V.

10.1101/2024.01.30.577913 — systems biology — Posted on 2024-01-31

29 SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss

Xi, X.; Liu, L.; Tuano, N.; Tailhades, J.; Mouradov, D.; Sieber, O.; Cryle, M.; Segelov, E.; Rosenbluh, J.

10.1101/2024.01.30.578083 — cancer biology — Posted on 2024-01-31

30 DBD-α4 helix of EWS::FLI is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

Bayanjargal, A.; Taslim, C.; Showpnil, I. A.; Selich-Anderson, J.; Crow, J. C.; Lessnick, S. L.; Theisen, E. R.

10.1101/2024.01.31.578127 — cancer biology — Posted on 2024-01-31

31 Structural dynamics and immunogenicity of the recombinant and outer membrane vesicle-embedded Meningococcal antigen NadA

Calvaresi, V.; Dello Iacono, L.; Borghi, S.; Luzzi, E.; Biolchi, A.; Benucci, B.; Ferlenghi, I.; Peschiera, I.; Giusti, F.; Fontana, L. E.; Kan, Z.-Y.; Spinello, Z.; Merola, M.; Delany, I.; Rand, K. D.; Norais, N.

10.1101/2024.01.30.577382 — biophysics — Posted on 2024-01-31

32 Endogenous labeling empowers accurate detection of m6A from single long reads of direct RNA sequencing

Guo, W.; Ren, Z.; Huang, X.; He, J.; Zhang, J.; Wu, Z.; Guo, Y.; Zhang, Z.; Cun, Y.; Wang, J.

10.1101/2024.01.30.577990 — bioinformatics — Posted on 2024-01-31

33 Protein language models learn evolutionary statistics of interacting sequence motifs

Zhang, Z.; Wayment-Steele, H. K.; Brixi, G.; Wang, H.; Dal Peraro, M.; Kern, D.; Ovchinnikov, S.

10.1101/2024.01.30.577970 — bioinformatics — Posted on 2024-01-31

34 Modeling metastatic progression from cross-sectional cancer genomics data

Rupp, K.; Lösch, A.; Hu, Y. L.; Nie, C.; Schill, R.; Klever, M.; Pfahler, S.; Grasedyck, L.; Wettig, T.; Beerenwinkel, N.; Spang, R.

10.1101/2024.01.30.577989 — bioinformatics — Posted on 2024-01-31

35 Structural basis of the Integrator complex assembly and association with transcription factors

Razew, M.; Fraudeau, A.; Pfleiderer, M. M.; Galej, W. P.

10.1101/2024.01.30.577955 — biochemistry — Posted on 2024-01-31

36 Host lipids regulate multicellular behavior of a predator of a human pathogen

Kidner, R. Q.; Goldstone, E. B.; Laidemitt, M. R.; Sanchez, M. C.; Gerdt, C.; Brokaw, L. P.; Ros-Rocher, N.; Morris, J.; Davidson, W. S.; Gerdt, J. P.

10.1101/2024.01.31.578218 — biochemistry — Posted on 2024-01-31

37 Structural Basis of Glutathione Recognition by the Yeast Cadmium Factor 1

Soong, T. H.; Hotze, C. F.; Khandelwal, N. K.; Tomasiak, T. M.

10.1101/2024.01.31.578287 — biochemistry — Posted on 2024-01-31

38 The proteostasis interactomes of trafficking-deficient KV11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue

Egly, C. L.; Do, T. Q.; McDonald, E. F.; Barny, L.; Plate, L.; Knollmann, B.

10.1101/2024.01.31.574410 — biochemistry — Posted on 2024-01-31

39 The crystal structure of the Shetha Protein II (FeSII) from Azotobacter vinelandii suggests a domain swap

Kabasakal, B. V.; McFarlane, C. R.; Cotton, C. A.; Schmidt, A.; Kung, A.; Lieber, L.; Murray, J. W.

10.1101/2024.01.30.575082 — biochemistry — Posted on 2024-01-31

40 Intermembrane space-localized twin Cx9C motif-containing TbTim15 is an essential subunit of the single mitochondrial inner membrane protein translocase of trypanosomes

von Kanel, C.; Oeljeklaus, S.; Wenger, C.; Stettler, P.; Harsman, A.; Warscheid, B.; Schneider, A.

10.1101/2024.01.31.578135 — biochemistry — Posted on 2024-01-31

41 Rapid QC-MS - Interactive Dashboard for Synchronous Mass Spectrometry Data Acquisition Quality Control

Gray, I. J.; Sandhu, W.; Lin, S.; Elias, J. E.; DeFelice, B. C.

10.1101/2024.01.30.578059 — biochemistry — Posted on 2024-01-31

42 Evolutionary innovation in conserved regulatory elements across the mammalian tree of life

Uebbing, S.; Kocher, A. A.; Baumgartner, M.; Ji, Y.; Bai, S.; Xing, X.; Nottoli, T.; Noonan, J. P.

10.1101/2024.01.31.578197 — evolutionary biology — Posted on 2024-01-31

43 Microbial community function increases host plant leaf growth in a pitcher plant experimental system

Bernardin, J. R.; Young, E. B.; Gray, S. M.; Bittleston, L. S.

10.1101/2024.01.30.578016 — ecology — Posted on 2024-01-31

44 Bacterium secretes chemical inhibitor that sensitizes competitor to bacteriophage infection

Zang, Z.; Zhang, C.; Park, K. J.; Schwartz, D. A.; Podicheti, R.; Lennon, J. T.; Gerdt, J. P.

10.1101/2024.01.31.578241 — microbiology — Posted on 2024-01-31

45 Large-Scale Evaluation of Spatial Metabolomics Protocols and Technologies

Saharuka, V.; Vieira, L. M.; Stuart, L.; Ekelöf, M.; Molenaar, M. R.; Bailoni, A.; Ovchinnikova, K.; Soltwisch, J.; Bausbacher, T.; Jakob, D.; King, M.; Müller, M. A.; Oetjen, J.; Pace, C.; Pinto, F. E.; Strittmatter, N.; Velickovic, D.; Spengler, B.; Muddiman, D. C.; Liebeke, M.; Janfelt, C.; Goodwin, R.; Eberlin, L. S.; Anderton, C. R.; Hopf, C.; Dreisewerd, K.; Alexandrov, T.

10.1101/2024.01.29.577354 — systems biology — Posted on 2024-01-31

46 The ESCRT protein CHMP5 promotes T cell leukemia by controlling BRD4-p300-dependent transcription

Umphred-Wilson, K. S.; Ratnayake, S.; Tang, Q.; Wang, R.; Devaiah, B. N.; Zhou, L.; Chen, Q.; Meerzaman, D.; Singer, D. S.; Adoro, S.

10.1101/2024.01.29.577409 — cancer biology — Posted on 2024-01-31

47 An isothermal calorimetry assay for determining steady state kinetic and enzyme inhibition parameters for SARS-CoV-2 3CL-protease

Mazzei, L.; Ranieri, S.; Greene-Cramer, R.; Cioffi, C.; Montelione, G. T.; Ciurli, S.

10.1101/2024.01.31.578159 — biochemistry — Posted on 2024-01-31

48 Nonreciprocal synchronization in embryonic oscillator ensembles

Ho, C.; Jutras-Dube, L.; Zhao, M.; Mönke, G.; Kiss, I. Z.; Francois, P.; Aulehla, A.

10.1101/2024.01.29.577856 — systems biology — Posted on 2024-01-31

49 Puzzle Hi-C: an accurate scaffolding software

Lin, G.; Huang, Z.; Yue, T.; Chai, J.; Li, Y.; Yang, H.; Qin, W.; Yang, G.; Murphy, R. W.; Zhang, Y.-p.; Zhang, Z.; Zhou, W.; Luo, J.

10.1101/2024.01.29.577879 — bioinformatics — Posted on 2024-01-31

50 Recurrent drought increases grassland community seasonal synchrony

Mueller, L. M.; Bahn, M.; Weidle, M.; Leitinger, G.; in 't Zandt, D.

10.1101/2024.01.29.577778 — ecology — Posted on 2024-01-31

51 AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes skin homeostasis against atopic dermatitis

Chen, Z.; Dragan, M.; Sun, P.; Haensel, D.; Vu, R.; Cui, L.; Shi, Y.; Dai, X.

10.1101/2024.01.29.577821 — molecular biology — Posted on 2024-01-31

52 Mapping patterns of thought onto brain activity during movie-watching

Wallace, R. S.; Mckeown, B.; Goodall-Halliwell, I.; Chitiz, L.; Forest, P.; Karapanagiotidis, T.; Mulholland, B.; Turnbull, A. G.; Vanderwal, T.; Hardikar, S.; Alam, T. G.; Bernhardt, B.; Wang, H.-T.; Strawson, W.; Milham, M.; Xu, T.; Margulies, D.; Poerio, G. L.; Jefferies, E. S.; Skipper, J. I.; Wammes, J.; Leech, R.; Smallwood, J.

10.1101/2024.01.31.578244 — neuroscience — Posted on 2024-01-31

53 Carrier-frequency specific omission-related neural activity in ordered sound sequences are independent of omissions-predictability

Hauswald, A.; Benz, K. R.; Hartmann, T.; Demarchi, G.; Weisz, N.

10.1101/2024.01.31.578194 — neuroscience — Posted on 2024-01-31

54 Impacts of Self-Administered 3,4-Methylenedioxypyrovalerone (MDPV) Alone, and in Combination with Caffeine, on Recognition Memory and Striatal Monoamine Neurochemistry in Male Sprague-Dawley Rats: Comparisons with Methamphetamine and Cocaine

Seaman, R. W.; Lamon, K.; Whitton, N.; Latimer, B.; Sulima, A.; Rice, K. C.; Murnane, K. S.; Collins, G. T.

10.1101/2024.01.31.578247 — pharmacology and toxicology — Posted on 2024-01-31

55 Quencher-free fluorescence monitoring of G-Quadruplex folding

Parada, Z.; Hoog, T.; Adamala, K.; Engelhart, A. E.

10.1101/2024.01.31.578026 — biophysics — Posted on 2024-01-31

56 StaVia: Spatially and temporally aware cartography with higher order random walks for cell atlases

Stassen, S. V.; Kobashi, M.; Huang, Y.; Ho, J. W. K.; Tsia, K.

10.1101/2024.01.29.577871 — bioinformatics — Posted on 2024-01-31

57 popDMS infers mutation effects from deep mutational scanning data

Hong, Z.; Barton, J. P.

10.1101/2024.01.29.577759 — bioinformatics — Posted on 2024-01-31

58 Aggregating Residue-Level Protein Language Model Embeddings with Optimal Transport

NaderiAlizadeh, N.; Singh, R.

10.1101/2024.01.29.577794 — bioinformatics — Posted on 2024-01-31

59 Toxin-based screening of C-terminal tags in Escherichia coli reveals the exceptional potency of ssrA-like degrons

Beardslee, P. C.; Schmitz, K. R.

10.1101/2024.01.29.576913 — biochemistry — Posted on 2024-01-31

60 Cryo-EM structures of the tubulin cofactors reveal the molecular basis for the biogenesis of alpha/beta-tubulin

Taheri, A.; Wang, Z.; Singal, B.; Guo, F.; Al-Bassam, J.

10.1101/2024.01.29.577855 — biochemistry — Posted on 2024-01-31

61 Discovery and Characterization of Terpene Synthases Powered by Machine Learning

Samusevich, R.; Hebra, T.; Bushuiev, R.; Bushuiev, A.; Chatpatanasiri, R.; Kulhanek, J.; Calounova, T.; Perkovic, M.; Engst, M.; Tajovska, A.; Sivic, J.; Pluskal, T.

10.1101/2024.01.29.577750 — biochemistry — Posted on 2024-01-31

62 Long G4-rich enhancer physically interacts with EXOC3 promoter via a G4:G4 DNA-based mechanism

DeMeis, J. D.; Roberts, J. T.; Delcher, H. A.; Godang, N. L.; Coley, A. B.; Brown, C. L.; Shaw, M. H.; Naaz, S.; Alsatari, E. S.; Dahal, A.; Alqudah, S. Y.; Nguyen, K. N.; Nguyen, A. D.; Paudel, S. S.; Dang, H.; O'Neal, W. K.; Knowles, M. R.; Houserova, D.; Gillespie, M. N.; Borchert, G. M.

10.1101/2024.01.29.577212 — genetics — Posted on 2024-01-31

63 Impact of inter-species hybridisation on antifungal drug response in the Saccharomyces genus.

Visinoni, F.; Royle, W.; Scholey, R.; Hu, Y.; Timouma, S.; Zeef, L.; Louis, E. J.; Delneri, D.

10.1101/2024.01.29.577396 — genetics — Posted on 2024-01-31

64 Effects of maize development and phenology on the field infestation dynamics of the European Corn Borer

Revillon, S.; Dillmann, C.; Galic, N.; Bauland, C.; Palaffre, C.; Malvar, R. A.; Butron, A.; Rebaudo, F.; Legrand, J.

10.1101/2024.01.29.577014 — ecology — Posted on 2024-01-31

65 Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion

Anaguano, D.; Adewale Fasoro, O.; Vick, G. S.; Blauwkamp, J. A.; Yanik, S.; Fierro, M. A.; Absalon, S.; SRINIVASAN, P.; Muralidharan, V.

10.1101/2024.01.29.577654 — cell biology — Posted on 2024-01-31

66 In turkeys, unlike chickens, the non-structural NS1 protein does not play a significant role in the replication and tissue tropism of the H7N1 avian influenza virus

Kuryshko, M.; Landmann, M.; Luttermann, C.; Ulrich, R.; Abdelwhab, E. M.

10.1101/2024.01.29.577768 — molecular biology — Posted on 2024-01-31

67 An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma

Holm, A.; Graus, M.; Wylie-Sears, J.; Borgelt, L.; Tan, J. W. H.; Nasim, S.; Chung, L.; Jain, A.; Sung, M.; Sun, L.; Brouillard, P.; Lekwuttikarn, R.; Kozakewich, H.; Qi, Y. J.; Teng, J.; Mulliken, J.; Vikkula, M.; Francois, M.; Bischoff, J.

10.1101/2024.01.29.577829 — molecular biology — Posted on 2024-01-31

68 Association of Blastocystis and Gut Microbiota in Type 2 Diabetic Mellitus Patients and Non-Diabetic Individuals.

Mohd Shaari, N. S.; Mohd Shaari, N. S.; Wan Sulaiman, W. S.; Omar, M. R.; Umaisara, N. A.; Lee, I. L.; Tengku Ahmad Basri, T. S. A.; Abdullah, N. S.

10.1101/2024.01.29.577889 — microbiology — Posted on 2024-01-31

69 The transcription factor IRF-5 is essential for the metabolic rewiring of CD8 T cells during chronic infection

Mai, L. T.; Swaminathan, S.; Nguyen, T. H.; Charpentier, T.; Loucif, H.; Carmona-Perez, L.; Lamarre, A.; Heinonen, K. M.; Fritz, J. H.; Stager, S.

10.1101/2024.01.29.577789 — immunology — Posted on 2024-01-31

70 The mitochondrial thiolase ACAT1 regulates monocyte/macrophage type I interferon via epigenetic control.

Wu, J.; SIngh, K.; Shing, V.; Gupta, A. K.; Huffstutler, R. D.; Lee, D.-Y.; Sack, M. N.

10.1101/2024.01.29.577773 — immunology — Posted on 2024-01-31

71 West Nile virus is transmitted within mosquito populations through infectious mosquito excreta

Hamel, R.; Narpon, Q.; Serrato-Pomar, I.; Gauliard, C.; Berthomieu, A.; Wichit, S.; Misse, D.; Sofonea, M. T.; Pompon, J.

10.1101/2024.01.29.577888 — zoology — Posted on 2024-01-31

72 More than a token photo: humanizing scientists enhances student engagement

Costello, R. A.; Driessen, E. P.; Kjelvik, M. K.; Schultheis, E. H.; Youngblood, R. M.; Zemenick, A. T.; Weber, M. G.; Ballen, C. J.

10.1101/2024.01.29.577791 — scientific communication and education — Posted on 2024-01-31

73 The interaction of relative age with maturation and body size in female handball talent selection based on only sport-specific criteria

Troznai, Z.; Utczas, K.; Papai, J.; Palinkas, G.; Szabo, T.; Petridis, L.

10.1101/2024.01.29.577867 — physiology — Posted on 2024-01-31

74 Blood flow occlusion superimposed on submaximal knee extensions does not evoke hypoalgesia: A pilot study

Morgan, S.-J.; Lemay, N.; Zhang, J.; Khaledi, N.; Aboodarda, S. J.

10.1101/2024.01.29.577836 — physiology — Posted on 2024-01-31

75 FtsZ-mediated spatial-temporal control over septal cell wall synthesis

Hu, L.; Perez, A.; Nesterova, T.; Lyu, Z.; Yahashiri, A.; Weiss, D. S.; Xiao, J.; Liu, J.

10.1101/2024.01.29.577872 — biophysics — Posted on 2024-01-31

76 iPAR: a new reporter for eukaryotic cytoplasmic protein aggregation

Lecinski, S.; MacDonald, C.; Leake, M. C.

10.1101/2024.01.29.577793 — biophysics — Posted on 2024-01-31

77 Inferring drift, genetic differentiation, and admixture graphs from low-depth sequencing data

Rasmussen, M. S.; Wiuf, C.; Albrechtsen, A.

10.1101/2024.01.29.577762 — bioinformatics — Posted on 2024-01-31

78 Comparing structure and dynamics of transition graphs by the symmetric difference metric over an edge-filtration

Garcia Pascual, B.; Salbu, L. M.; Renz, J.; Giannakis, K.; Johnston, I.

10.1101/2024.01.29.577802 — bioinformatics — Posted on 2024-01-31

79 scCensus: Off-target scRNA-seq reads reveal meaningful biology

He, D.; Mount, S. M.; Patro, R.

10.1101/2024.01.29.577807 — bioinformatics — Posted on 2024-01-31

80 Immunomodulatory Porous Regenerative Scaffolds for in situ Vascular Engineering

Zhen, L.; Quiroga, E.; Creason, S. A.; Chen, N.; Sapre, T. R.; Snyder, J. M.; Lindhartsen, S. L.; Fountaine, B. S.; Barbour, M. C.; Faisal, S.; Aliseda, A.; Johnson, B. W.; Himmelfarb, J.; Ratner, B. D.

10.1101/2024.01.29.577757 — bioengineering — Posted on 2024-01-31

81 High-throughput single-cell, single-mitochondrial DNA assay using hydrogel droplet microfluidics

Park, J.; Kadam, P. S.; Atiyas, Y.; Chhay, B.; Tsourkas, A.; Eberwine, J. H.; Issadore, D. A.

10.1101/2024.01.29.577854 — bioengineering — Posted on 2024-01-31

82 Postharvest partial dehydration of blueberries enhanced blueberry wine aroma via upregulating phenylalanine metabolism and terpene biosynthesis

Wang, Y.; Zhang, Q.; Yang, Q.; Bian, C.; Huang, S.-Q.; Zhao, L.-L.; Huang, Y.-Q.; Chen, Q.; Zhang, H.-W.; Gao, X.-L.

10.1101/2024.01.29.577155 — biochemistry — Posted on 2024-01-31

83 Genetic diversity within diagnostic sputum samples is mirrored in the culture of Mycobacterium tuberculosis

Mariner-Llicer, C.; Goig, G. A.; Torres-Puente, M.; Vashakidze, S.; Villamayor, L.; Saavedra-Cervera, B.; Mambuque, E.; Khurtsilava, I.; Avaliani, Z.; Rosenthal, A.; Gabrielian, A.; Shurgaia, M.; Shubladze, N.; Garcia-Basteiro, A. L.; Lopez, M.; Comas, I.

10.1101/2024.01.30.577772 — genomics — Posted on 2024-01-31

84 scMicrobe PTA: Near Complete Genomes From Single Bacterial Cells

Bowers, R. M.; Gonzalez-Pena, V.; Wardhani, K.; Goudeau, D.; Blow, M. J.; Udwary, D.; Klein, D.; Vill, A. C.; Brito, I. L.; Woyke, T.; Malmstrom, R.; Gawad, C.

10.1101/2024.01.30.577819 — genomics — Posted on 2024-01-31

85 Multiplex PCR reveals population structure in an inbred communal bird.

Babaei, S.; Grieves, L.; Evans, B.; Quinn, J. S.

10.1101/2024.01.29.577869 — genetics — Posted on 2024-01-31

86 Dysregulated SASS6 expression promotes increased ciliogenesis and cell invasion phenotypes

Hargreaves, E.; Jenks, A. D.; Staszewski, A. S.; Tsalikis, A.; Bodoque Villar, R.; Arias Garcia, M.; Abdi, Y.; Al-Malki, A.; Yuan, Y.; Natrajan, R.; Haider, S.; Iskratsch, T.; Wang, W.-J.; Godinho, S.; Palaskas, N. J.; Calvo, F.; Zech, T. N.; TANOS, B. E.

10.1101/2024.01.29.576599 — cell biology — Posted on 2024-01-31

87 Inheritance of old mitochondria controls early CD8+ T cell fate commitment and is regulated by autophagy

Borsa, M.; Lechuga-Vieco, A. V.; Kayvanjoo, A. H.; Yazicioglu, Y.; Compeer, E. B.; Richter, F. C.; Bui, H.; Dustin, M. L.; Katajisto, P.; Simon, A. K.

10.1101/2024.01.29.577412 — cell biology — Posted on 2024-01-31

88 Lysosomal degradation of ACVR1-Activin complexes negatively regulates signaling of Activins and Bone Morphogenetic Proteins

Hom, W. W.; Aykul, S.; Panagis, L.; Patel, K.; Brydges, S.; Goebel, E. J.; Hart, K. N.; Lees-Shepard, J. B.; Hatsell, S. J.; Idone, V.; Economides, A. N.

10.1101/2024.01.29.577837 — cell biology — Posted on 2024-01-31

89 In-silico Drug Repurposing pipeline for Epilepsy: Integrating Deep Learning and Structure-based Approaches

Lv, X.; Wang, J.; Yuan, Y.; Pan, L.; Guo, J.

10.1101/2024.01.29.577686 — pharmacology and toxicology — Posted on 2024-01-31

90 BioXNet: a biologically inspired neural network for deciphering anti-cancer drug response in precision medicine

Yang, J.; Wu, W. K. K.; Hui, R. Y. M.; Wong, I. C. K.; Zhang, Q.

10.1101/2024.01.29.576766 — cancer biology — Posted on 2024-01-31

91 Modeling platinum resistance in a stem-like patient-derived ovarian cancer sample

Suzuki, T.; Conant, A. B.; Jung, Y.; Bax, R.; Antonissen, A.; Chen, W.; Yu, G.; Ioffe, Y. J.; Wang, C.; Unternaehrer, J. J.

10.1101/2024.01.30.577975 — cancer biology — Posted on 2024-01-31

92 RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

Dumas, L.; Shin, S.; Rigaud, Q.; Cargnello, M.; Hernandez-Suarez, B.; Herviou, P.; Saint-Laurent, N.; Leduc, M.; Le Gall, M.; Monchaud, D.; Dassi, E.; Cammas, A.; Millevoi, S.

10.1101/2024.01.29.577192 — cancer biology — Posted on 2024-01-31

93 The interplay between peptides and RNA is critical for protoribosome compartmentalization and stability

Codispoti, S.; Yamaguchi, T.; Makarov, M.; Giacobelli, V. G.; Masek, M.; Kolar, M. H.; Sanchez Rocha, A. C.; Fujishima, K.; Zanchetta, G.; Hlouchova, K.

10.1101/2024.01.29.577748 — biophysics — Posted on 2024-01-31

94 Machine Learning-Based Identification of B4GALNT1 as a Key Player in Hepatocellular Carcinoma: A Comprehensive Bioinformatics and Structural Analysis

Verma, R. K.; Lokhande, K. B.; Srivastava, P. K.; Singh, A.

10.1101/2024.01.29.577885 — bioinformatics — Posted on 2024-01-31

95 Orthology inference at scale with FastOMA

Majidian, S.; Nevers, Y.; Yazdizadeh Kharrazi, A.; Warwick Vesztrocy, A.; Pascarelli, S.; Moi, D.; Glover, N.; Altenhoff, A. M.; Dessimoz, C.

10.1101/2024.01.29.577392 — bioinformatics — Posted on 2024-01-31

96 Systematic investigation of interindividual variation of DNA methylation in human whole blood

Grant, O. A.; Kumari, M.; Schalkwyk, L. C.; Zabet, N. R.

10.1101/2024.01.29.577703 — genomics — Posted on 2024-01-31

97 Isoform-level profiling of m6A epitranscriptomic signatures in human brain

Gleeson, J.; Madugalle, S. U.; McLean, C.; Bredy, T. W.; De Paoli-Iseppi, R.; Clark, M. B.

10.1101/2024.01.31.578088 — genomics — Posted on 2024-01-31

98 DE Novo emerged gene SEarch in Eukaryotes with DENSE

Roginski, P.; Grandchamp, A.; Quignot, C.; Lopes, A.

10.1101/2024.01.30.578014 — genomics — Posted on 2024-01-31

99 Diving into broad-scale and high-resolution population genomics to decipher drivers of structure and climatic vulnerability in a marine invertebrate

Bourret, A.; Leung, C.; Puncher, G. N.; Le Corre, N.; Deslauriers, D.; Skanes, K.; Bourdages, H.; Cassista-Da Ros, M.; Walkusz, W.; Jeffery, N. W.; Stanley, R. R.; Parent, G. J.

10.1101/2024.01.29.577252 — genomics — Posted on 2024-01-31

100 Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome

Nguyen, J.; Win, P. W.; Nagano, T. S.; Shin, E. H.; Newcomb, C.; Arking, D. E.; Castellani, C. A.

10.1101/2024.01.29.577835 — genomics — Posted on 2024-01-31

101 Variant calling and genotyping accuracy of ddRAD-seq: comparison with 20X WGS in layers

Doublet, M.; Degalez, F.; Lagarrigue, S.; Lagoutte, L.; Gueret, E.; Allais, S.; Lecerf, F.

10.1101/2024.01.29.577880 — genomics — Posted on 2024-01-31

102 A comparison between low-cost library preparation kits for low coverage sequencing

Stewart, C. M.; Gibson, M. J.; Parsa, J.-Y.; Li, J. H.

10.1101/2024.01.30.578044 — genomics — Posted on 2024-01-31

103 Genome-wide maps of highly-similar intrachromosomal repeats that mediate ectopic recombination in three human genome assemblies

Fernandez-Luna, L.; Aguilar-Perez, C.; Grochowski, C. M.; Mehaffey, M.; Carvalho, C. M. B.; Gonzaga-Jauregui, C.

10.1101/2024.01.29.577884 — genomics — Posted on 2024-01-31

104 The Primula edelbergii S-locus is an example of a jumping supergene

Potente, G.; Yousefi, N.; Keller, B.; Mora-Carrera, E.; Szovenyi, P.; Conti, E.

10.1101/2024.01.30.577918 — genomics — Posted on 2024-01-31

105 Decreased Left Atrial Cardiomyocyte FGF13 Expression Increases Vulnerability to Postoperative Atrial Fibrillation in Humans

Fischer, M. A.; Arrieta, A.; Angelini, M.; Soehalim, E.; Chapski, D. J.; Shemin, R. J.; Vondriska, T. M.; Olcese, R.

10.1101/2024.01.30.577790 — genomics — Posted on 2024-01-31

106 Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin.

Fallon, T. R.; Shende, V. V.; Wierzbicki, I. H.; Auber, R. P.; Gonzalez, D. J.; Wisecaver, J. H.; Moore, B. S.

10.1101/2024.01.29.577497 — genomics — Posted on 2024-01-31

107 Efficient CRISPR genome editing and integrative genomic analyses reveal the mosaicism of Cas-induced mutations and pleiotropic effects of scarlet gene in an emerging model system

Xu, S.; Neupane, S.; Wang, H.; Pham, T.; Snyman, M.; Huynh, T.; Wang, L.

10.1101/2024.01.29.577787 — genomics — Posted on 2024-01-31

108 The limits of predicting maladaptation to future environments with genomic data

Lind, B. M.; Lotterhos, K. E.

10.1101/2024.01.30.577973 — genomics — Posted on 2024-01-31

109 Characterizing substructure via mixture modeling of genetic similarity in large-scale summary statistics

Stoneman, H. R.; Price, A.; Scribner-Trout, N.; Lamont, R.; Tifour, S.; Pozdeyev, N.; Crooks, K.; Lin, M.; Rafaels, N.; Marker, K. M.; Gignoux, C. R.; Hendricks, A. E.

10.1101/2024.01.29.577805 — genomics — Posted on 2024-01-31

110 Gene-specific RNA homeostasis revealed by perturbation of the NuA4/Tip60 acetyltransferase complex

Forouzanfar, F.; Plassard, D.; Furst, A.; Moreno, D.; Oliveira, K. A.; Reina-San-Martin, B.; Tora, L.; Molina, N.; Mendoza, M.

10.1101/2024.01.30.577960 — genomics — Posted on 2024-01-31

111 Assessing the effects of acute temperature changes of sea water temperature due to climate change on Scottish farmed Atlantic salmon and investigating genetic mitigation

Tsairidou, S.; van den Berg, J.; Tapping, S.; Sobolewska, H.; Hamilton, A.

10.1101/2024.01.29.577726 — genetics — Posted on 2024-01-31

112 Lead in the head: persistent lead poisoning of waterfowl in the Camargue (southern France) ten years after the ban on the use of lead shot in wetlands

Bechet, A.; Olivier, A.; Cavallo, F.; Sauvajon, L.; Champagnon, J.; Defos-Durau, P.; Mondain-Monval, J.-Y.

10.1101/2024.01.29.577719 — ecology — Posted on 2024-01-31

113 Screening for metastasis-related genes in mouse melanoma cells through sequential tail vein injection

Hao, Q.; Shen, J.; Sang, L.; Bai, Y.; sun, j.

10.1101/2024.01.29.577709 — cell biology — Posted on 2024-01-31

114 Localization of S1P1 Receptor Signaling in the rat, mouse and human Central Nervous System

Martinez-Gardeazabal, J.; Pereira-Castelo, G.; Moreno-Rodriguez, M.; Llorente-Ovejero, A.; Fernandez-Martinez, M.; Fernandez-Vega, I.; Manuel, I.; Rodriguez-Puertas, R.

10.1101/2024.01.29.577735 — pharmacology and toxicology — Posted on 2024-01-31

115 Chloride binding and cholesterol effects on high frequency complex nonlinear capacitance (cNLC) in the mouse outer hair cell: experiment and molecular dynamics

Bai, J.-P.; Zhang, C.; Renigunta, V.; Oliver, D.; Navaratnam, D. S.; Beckstein, O.; Santos-Sacchi, J.

10.1101/2024.01.29.577264 — biophysics — Posted on 2024-01-31

116 Caspase-1 in Cx3cr1-expressing cells drives an IL-18-dependent T cell response that promotes parasite control during acute T. gondii infection

Babcock, I. W.; Sibley, L. A.; Labuzan, S. A.; Cowan, M. N.; Sethi, I.; Alemu, S.; Kovacs, M. A.; Lukens, J. R.; Harris, T. H.

10.1101/2024.01.29.577694 — immunology — Posted on 2024-01-31

117 A Simple and Rapid Protocol for the Isolation of Murine Bone Marrow Suitable for the Differentiation of Dendritic Cells

Song, R.; Bafit, M.; Tullett, K. M.; Tan, P. S.; Lahoud, M. H.; O'Keeffe, M.; Purcell, A. W.; Braun, A.

10.1101/2024.01.29.577349 — immunology — Posted on 2024-01-31

118 IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in vivo

Yong, C. S. M.; Telarovic, I.; Gregor, L.; Raeber, M. E.; Pruschy, M.; Boyman, O.

10.1101/2024.01.29.577732 — immunology — Posted on 2024-01-31

119 Body temperature regulates glucose metabolism and torpid

Lee, M.-l.; Chang, C.-P.; Toda, C.; Nemoto, T.; Enoki, R.

10.1101/2024.01.29.577738 — physiology — Posted on 2024-01-31

120 Evaluation of homologous recombination repair status in metastatic prostate cancer by next-generation sequencing and functional tissue-based immunofluorescence assays

Arce-Gallego, S.; Morgado, P. C.; Delgado-Serrano, L.; Simonetti, S.; Gonzalez, M.; Marmolejo, D.; Morales-Barrera, R.; Mir, G.; Semidey, M. E.; Lozano, P. R.; Cordoba-Terreros, S.; Mast, R.; de Albert, M.; Planas, J.; Cuadras, M.; Maldonado, X.; Suarez, C.; Casanova-Salas, I.; Nonell, L.; Dienstmann, R.; Nuciforo, P.; Vivancos, A.; Llop-Guevara, A.; Carles, J.; Serra, V.; Mateo, J.

10.1101/2024.01.28.577367 — cancer biology — Posted on 2024-01-31

121 Organic macromolecules bind a significant proportion of the precursor calcium for nacre formation.

Macias-Sanchez, E.; Willinger, M. G.; Huang, X.; Checa, A. G.

10.1101/2024.01.28.577631 — biophysics — Posted on 2024-01-31

122 BOLDsωimsuite: A new software suite for forward modeling of the BOLD fMRI signal

Chausse, J.; Berman, A. J. L.; Chen, J. J.

10.1101/2024.01.28.577679 — biophysics — Posted on 2024-01-31

123 Investigating the mechanisms of enzyme diffusion using mass photometry

Yancheva, Y. D.; Kaya, S. G.; Fraaije, M. W.; Tych, K.

10.1101/2024.01.28.577687 — biophysics — Posted on 2024-01-31

124 Imaging Abeta aggregation by liquid-phase transmission electron microscopy

Ing, G.; Acosta-Gutierrez, S.; Vendruscolo, M.; Battaglia, G.; Ruiz-Perez, L.

10.1101/2024.01.29.577710 — biophysics — Posted on 2024-01-31

125 Floria: Fast and accurate strain haplotyping in metagenomes

Shaw, J.; Gounot, J.-S.; Chen, H.; Nagarajan, N.; Yu, Y. W.

10.1101/2024.01.28.577669 — bioinformatics — Posted on 2024-01-31

126 Predicting protein functions using positive-unlabeled ranking with ontology-based priors

Zhapa-Camacho, F.; Tang, Z.; Kulmanov, M.; Hoehndorf, R.

10.1101/2024.01.28.577662 — bioinformatics — Posted on 2024-01-31

127 Approximate Nearest Neighbor Graph Provides Fast and Efficient Embedding with Applications in Large-scale Biological Data

Zhao, J.; Pierre-Both, J.; Konstantinidis, K. T.

10.1101/2024.01.28.577627 — bioinformatics — Posted on 2024-01-31

128 A systematic evaluation of computation methods for cell segmentation

Wang, Y.; Zhao, J.; Xu, H.; Han, C.; Tao, Z.; Zhao, D.; Zhou, D.; Tong, G.; Liu, D.; Ji, Z.

10.1101/2024.01.28.577670 — bioinformatics — Posted on 2024-01-31

129 PTF-Vac: Ab-initio discovery of plant transcription factors binding sites using deep co-learning encoders-decoders

Gupta, S.; Jyoti, ; Bhati, U.; Kesarwani, V.; Shankar, R.

10.1101/2024.01.28.577608 — bioinformatics — Posted on 2024-01-31

130 Conway-Bromage-Lyndon (CBL): an exact, dynamic representation of k-mer sets

Martayan, I.; Cazaux, B.; Limasset, A.; Marchet, C.

10.1101/2024.01.29.577700 — bioinformatics — Posted on 2024-01-31

131 Sustaining healthy long-term host-microbiome interactions in a physiologically relevant dynamic gingival tissue model

Adelfio, M.; Callen, G. E.; Diaz, A. R.; Paster, B. J.; He, X.; Hasturk, H.; Ghezzi, C. E.

10.1101/2024.01.28.577629 — bioengineering — Posted on 2024-01-31

132 Repairing a deleterious domestication variant in a floral regulator of tomato by base editing

Glaus, A. N.; Brechet, M.; Lebeigle, L.; Iwaszkiewicz, J.; Ambrosini, G.; Julca, I.; Zhang, J.; Roberts, R.; Iseli, C.; Guex, N.; Jimenez-Gomez, J. M.; Glover, N.; Martin, G. B.; Strickler, S. R.; Soyk, S.

10.1101/2024.01.29.577624 — genetics — Posted on 2024-01-31

133 Genetic Dynamics of Mustang and Feral Horse Populations in the Western United States

Cothran, E. G.; Khanshour, A.; Funk, S. M. W.; Conant, E.; Juras, R.; Davis, B. W.

10.1101/2024.01.28.577652 — genetics — Posted on 2024-01-31

134 Hurdles to Horizontal Gene Transfer: Synonymous variation determines antibiotic resistance phenotype across species

Finnegan, M.; Rose, C. J.; Hamet, J.; Prat, B.; Bedhomme, S.

10.1101/2024.01.28.576264 — evolutionary biology — Posted on 2024-01-31

135 Mitochondrial DNA analysis in ayu (Plecoglossus altivelis) raises an urgent conservation need for its southernmost population

Ha, L. M.; Tran, H. D.; Takeshima, H.; Iguchi, K.

10.1101/2024.01.28.577666 — ecology — Posted on 2024-01-31

136 A taxonomy based on acoustic features of some Iranian cicadas and calling song description of Chloropsalta smaragdula Haupt, 1920 (Hem: Cicadidae) from Isfahan, Iran

Mehdipour, M.; Reide, K.; Sendi, J. J.; Zamanian, H.; Mohammadi-Mobarakeh, A.

10.1101/2024.01.28.577653 — ecology — Posted on 2024-01-31

137 Unusual migratory strategy a key factor driving interactions at wind energy facilities in at-risk bats

Campbell, C. J.; Nelson, D. M.; Nagel, J.; Clerc, J.; Weller, T. J.; Weiringa, J. G.; Fraser, E.; Longstaffe, F. J.; Hale, A. M.; Lout, M.; Pruitt, L.; Guralnick, R.; Zanden, H. B. V.

10.1101/2024.01.28.577637 — ecology — Posted on 2024-01-31

138 A β-catenin:MSI2 axis regulates the expression of LEF1 and subsequent human haematopoietic stem/progenitor cell proliferation

Morgan, R. G.; Wagstaff, M.; Nguyen, D. T.; Blair, A.; Towler, B. P.; Newbury, S. F.

10.1101/2024.01.28.577638 — cell biology — Posted on 2024-01-31

139 Crossover Interference Mediates Multiscale Patterning Along Meiotic Chromosomes

White, M. A.; Weiner, B.; Chu, L.; Lim, G.; Kleckner, N. E.

10.1101/2024.01.28.577645 — cell biology — Posted on 2024-01-31

140 Unravelling the ageing-reversal potency of stem cell-derived extracellular vesicles in a rat model of premature cardiac senescence

Gomez-Cid, L.; Campo-Fonseca, A.; Cervera-Negueruela, M.; Ocampo, A.; G Pinto, A.; Gil-Jaurena, J. M.; Suarez-Sancho, S.; Fernandez-Aviles, F.; Bermejo, J.; Grigorian-Shamagian, L.

10.1101/2024.01.28.577660 — cell biology — Posted on 2024-01-31

141 Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity

Yang, X.; Meng, F.; Wei, R.; Liu, D.; Gong, X.; Ruvkun, G.; Wei, W.

10.1101/2024.01.28.577665 — cell biology — Posted on 2024-01-31

142 IL-1beta-induced epithelial cell and fibroblast transdifferentiation fuels neutrophil recruitment in chronic rhinosinusitis with nasal polyps

Xie, X.; Wang, P.; Jin, M.; Wang, Y.; Qi, L.; Wu, C.; Guo, S.; Li, C.; Zhang, X.; Yuan, Y.; Ma, X.; Liu, F.; Liu, W.; Liu, H.; Duan, C.; Ye, P.; Li, X.; Larry, B.; Zhao, W.; Feng, X.

10.1101/2024.01.28.576762 — immunology — Posted on 2024-01-31

143 An integrated signaling threshold initiates IgG response towards virus-like immunogens

Wholey, W.; Meyer, A. R.; Yoda, S.-T.; Mueller, J. L.; Mathenge, R.; Chackerian, B.; Zikherman, J.; Cheng, W.

10.1101/2024.01.28.577643 — immunology — Posted on 2024-01-31

144 Early parafoveal semantic integration in natural reading

Pan, Y.; Frisson, S.; Federmeier, K. D.; Jensen, O.

10.1101/2022.09.26.509511 — neuroscience — Posted on 2024-01-31

145 Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylation of various flavonoids

Frommann, J.-F.; Pucker, B.; Sielmann, L. M.; Muller, C.; Weisshaar, B.; Stracke, R.; Schweiger, R.

10.1101/2024.01.30.577901 — plant biology — Posted on 2024-01-31

146 The Arabidopsis leucine rich repeat receptor-like kinase MIK2 interacts with RKS1 and participates to the control of quantitative disease resistance to the bacterial pathogen Xanthomonas campestris

Delplace, F.; Huard-Chauveau, C.; Roux, F.; Roby, D.

10.1101/2024.01.29.577741 — plant biology — Posted on 2024-01-31

147 BERTE：High-precision hierarchical classification of transposable elements by a transfer learning method with BERT pre-trained model and convolutional neural network

Chen, Y.; Qi, Y.; Wu, Y.; Zhang, F.; Liao, X.; Shang, X.

10.1101/2024.01.28.577612 — bioinformatics — Posted on 2024-01-31

148 Community structure of heritable viruses in a Drosophila-parasitoids complex

Varaldi, J.; Lepetit, D.; Burlet, N.; Faber, C.; Baretje, B.; Allemand, R.

10.1101/2023.07.29.551099 — evolutionary biology — Posted on 2024-01-31

149 Impacts of global food supply on biodiversity via land use and climate change

Boakes, E. H.; Dalin, C.; Etard, A.; Newbold, T.

10.1101/2023.05.03.539201 — ecology — Posted on 2024-01-31

150 Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: optimizing DNA repair factor activity through opposing regulations

Zahid, S. S.; Aloe, S.; Sutherland, J.; Holloman, W. K.; Lue, N.

10.1101/2023.04.17.537176 — molecular biology — Posted on 2024-01-31

151 Detailing organelle division and segregation in Plasmodium falciparum

Verhoef, J. M. J.; Boshoven, C.; Evers, F.; Akkerman, L. J.; Gijsbrechts, B. C. A.; van de Vegte-Bolmer, M.; van Gemert, G.-J.; Vaidya, A. B.; Kooij, T. W. A.

10.1101/2024.01.30.577899 — microbiology — Posted on 2024-01-31

152 Functional magnetic resonance imaging of the lumbosacral cord during a lower extremity motor task

Kündig, C. W.; Finsterbusch, J.; Freund, P.; David, G.

10.1101/2024.01.31.577917 — neuroscience — Posted on 2024-01-31

153 Trained recurrent neural networks develop phase-locked limit cycles in a working memory task

Pals, M.; Macke, J. H.; Barak, O.

10.1101/2023.04.11.536352 — neuroscience — Posted on 2024-01-31

154 The HSFA1a is stabilized by the co-chaperone HSP70-HSP90 organizing protein HOP in Arabidopsis

Toribio, R.; Navarro, A.; Castellano, M. M.

10.1101/2024.01.30.577911 — plant biology — Posted on 2024-01-31

155 Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance and resetting in winter wheat

Liu, X.; Lin, X.; Deng, M.; Shi, B.; Chen, J.; Li, H.; Xu, S.; Bie, X.; Zhang, X.; Chong, K.; Xiao, J.

10.1101/2023.12.19.572364 — plant biology — Posted on 2024-01-31

156 Piscis: a novel loss estimator of the F1 score enables accurate spot detection in fluorescence microscopy images via deep learning

Niu, Z.; O'Farrell, A.; Li, J.; Reffsin, S.; Jain, N.; Dardani, I.; Goyal, Y.; Raj, A.

10.1101/2024.01.31.578123 — bioinformatics — Posted on 2024-01-31

157 scPathoQuant: A tool for efficient alignment and quantification of pathogen sequence reads from 10x single cell sequencing data sets

Whitmore, L. S.; Tisoncik-Go, J.; Gale, M.

10.1101/2023.07.21.549987 — bioinformatics — Posted on 2024-01-31

158 TIPP_plastid: A user-friendly tool for de novo assembly of plastid genomes

Xian, W.; Weigel, D.

10.1101/2024.01.29.577798 — genomics — Posted on 2024-01-31

159 Human stem cell model of neural crest cell differentiation reveals a requirement of SF3B4 in survival, maintenance, and differentiation

Griffin, C.; Saint-Jeannet, J.-P.

10.1101/2024.01.25.577202 — developmental biology — Posted on 2024-01-31

160 ESPressoscope: a small and powerful platform for in situ microscopy

Li, E.; Saggiomo, V.; Ouyang, W.; Prakash, M.; Diederich, B.

10.1101/2024.01.20.576174 — microbiology — Posted on 2024-01-31

161 Recording gamma-secretase activity in living mouse brains

Hou, S. S.; Ikegawa, Y.; Kwon, Y.; Houser, M. C. Q.; Lundin, B.; Bacskai, B. J.; Berezovska, O.; Maesako, M.

10.1101/2024.01.31.578105 — neuroscience — Posted on 2024-01-31

162 Incorporation of a cost of deliberation time in perceptual decision making

Kira, S.; Zylberberg, A.; Shadlen, M. N.

10.1101/2024.01.31.578067 — neuroscience — Posted on 2024-01-31

163 Archaeological Ivories: A practical guide for identifying elephant and hippo ivory in the archaeological record

Shochat, H.

10.1101/2024.01.27.576203 — zoology — Posted on 2024-01-31

164 Rubisco supplies pyruvate for the 2-C-methyl-D-erythritol-4-phosphate pathway in Arabidopsis

Evans, S. E.; Xu, Y.; Bergman, M. E.; Ford, S.; Liu, Y.; Sharkey, T.; Phillips, M. A.

10.1101/2024.01.28.577108 — plant biology — Posted on 2024-01-31

165 The MKK3 MAPK cascade integrates temperature and after-ripening signals to modulate seed germination

Otani, M.; Tojo, R.; Regnard, S.; Zheng, L.; Hoshi, T.; Ohmori, S.; Tachibana, N.; Sano, T.; Koshimizu, S.; Ichimura, K.; Colcombet, J.; Kawakami, N.

10.1101/2024.01.28.577514 — plant biology — Posted on 2024-01-31

166 An analysis of natural variation in Pinus pinaster through the lens of systems biology

Pascual, J.; Lopez-Hidalgo, C.; Feito, I.; Majada, J.; Meijon, M.

10.1101/2024.01.29.577781 — plant biology — Posted on 2024-01-31

167 The MKK3 module integrates nitrate and light signals to modulate secondary dormancy in Arabidopsis thaliana

Regnard, S.; Otani, M.; Keruzore, M.; Teinturier, A.; Blondel, M.; Kawakami, N.; Krapp, A.; Colcombet, J.

10.1101/2024.01.28.577345 — plant biology — Posted on 2024-01-31

168 A transcriptomic study of PF06830 root cap proteins

raymond, j. a.

10.1101/2024.01.29.577848 — plant biology — Posted on 2024-01-31

169 Disease resistance of Brassica juncea to Sclerotinia sclerotiorum is established through the induction of indole glucosinolate biosynthesis

Zhang, J.; Yang, X.; Jiang, Y.; Jin, H.; Yu, K.; Xiao, L.; Ouyang, Q.; Tian, E.

10.1101/2024.01.29.577696 — plant biology — Posted on 2024-01-31

170 A study on tomato brown rugose fruit virus longevity in soil and virion susceptibility to various pH treatments contributes to optimization of a soil disinfection protocol

Molad, O.; Smith, E.; Luria, N.; Bakelman, E.; Lachman, O.; Reches, M.; Dombrovsky, A.

10.1101/2024.01.29.577727 — plant biology — Posted on 2024-01-31

171 RNA N6-adenine methylation dynamics impact Hyaloperonospora arabidopsidis resistance in Arabidopsis

Furci, L.; Berthelier, J.; Saze, H.

10.1101/2024.01.30.577950 — plant biology — Posted on 2024-01-31

172 Application of the thermal death time model in predicting thermal damage accumulation in plants

Faber, A. H.; Oersted, M.; Ehlers, B. K.

10.1101/2024.01.29.577815 — plant biology — Posted on 2024-01-31

173 Fluorescence hybridization chain reaction enables localization of multiple molecular classes combined with plant cell ultrastructure

Yu, Y.; Huss, D. J.; Li, M. J.; Wickramanayake, J. S.; Belanger, S.; Klebanovych, A.; Meyers, B. C.; Kellogg, E. A.; Czymmek, K. J.

10.1101/2024.01.29.577761 — plant biology — Posted on 2024-01-31

174 Cluster effect through the oligomerisation of bioactive disaccharide AMOR on pollen tube capacitation in Torenia fournieri

Mizukami, A. G.; Kusano, S.; Hagihara, S.; Higashiyama, T.

10.1101/2024.01.30.574946 — biochemistry — Posted on 2024-01-31

175 KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy

de Talhouet, C.; Esteras Gallego, N.; Soutar, M. P. M.; O'Callaghan, B.; Plun-Favreau, H.

10.1101/2023.08.03.551835 — neuroscience — Posted on 2024-01-31

176 A spinal cord injury time and severity consensus transcriptomic reference suite in rat reveals translationally-relevant biomarker genes

Grillo-Risco, R.; Hidalgo, M. R.; Martinez-Rojas, B.; Moreno-Manzano, V.; Garcia-Garcia, F.

10.1101/2024.01.30.578030 — neuroscience — Posted on 2024-01-31

177 Spatiotemporal orchestration of calcium-cAMP oscillations on AKAP/AC nanodomains is governed by an incoherent feedforward loop

Qiao, L.; Getz, M.; Gross, B.; Tenner, B.; Zhang, J.; Rangamani, P.

10.1101/2024.01.29.577875 — systems biology — Posted on 2024-01-31

178 Cost-benefit analysis of cryogenic electron tomography subtomogram averaging of chaperonin MmCpn at near atomic resolution.

Zhao, Y.; Schmid, M. F.; Chiu, W.

10.1101/2024.01.30.577584 — biophysics — Posted on 2024-01-31

179 scGND: Graph neural diffusion model enhances single-cell RNA-seq analysis

Liu, Y.-C.; Zou, A.; Lu, S. L.; Lee, J.-H.; Wang, J.; Zhang, C.

10.1101/2024.01.28.577667 — bioinformatics — Posted on 2024-01-31

180 Projections from thalamic nucleus reuniens to hippocampal CA1 area enable context value updating

Ziołkowska, M.; Sotoudeh, N.; Cały, A.; Puchalska, M.; Pagano, R.; Sliwinska, M. A.; Salamian, A.; Radwanska, K.

10.1101/2024.01.31.578155 — animal behavior and cognition — Posted on 2024-01-31

181 Improving data archiving practices in ancient genomics

Bergström, A.

10.1101/2023.05.15.540553 — genomics — Posted on 2024-01-31

182 PI(4,5)P2 role in Transverse-tubule membrane formation and muscle function

Fujita, N.; Girada, S.; Vogler, G.; Bodmer, R.; Kiger, A. A.

10.1101/2024.01.31.578124 — cell biology — Posted on 2024-01-31

183 The evolutionary origins of the lysosome-related organelle sorting machinery reveal fundamental homology in post-endosome trafficking pathways

More, K. J.; Dacks, J. B.; Manna, P. T.

10.1101/2024.01.30.578091 — cell biology — Posted on 2024-01-31

184 The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei

Link, F.; Jung, S.; Malzer, X.; Zierhut, F.; Konle, A.; Borges, A.; Batters, C.; Weiland, M.; Poellmann, M.; Nguyen, A. B.; Kullmann, J.; Veigel, C.; Engstler, M.; Morriswood, B.

10.1101/2024.01.29.577824 — cell biology — Posted on 2024-01-31

185 Reduction of chemokine CXCL9 expression by omega-3 fatty acids via ADP-ribosylhydrolase ARH3 in MIN6 insulin-producing cells

You, Y.; Sarkar, S.; Deiter, C.; Elliott, E.; Nicora, C.; Mirmira, R.; Sussel, L.; Nakayasu, E.

10.1101/2024.01.30.578079 — cell biology — Posted on 2024-01-31

186 Orc6 dissociation from chromatin prevents premature loading of MCM at G2 and tetraploid production

Hayashi-Takanaka, Y.; Hiratani, I.; Haraguchi, T.; Hiraoka, Y.

10.1101/2024.01.30.577900 — cell biology — Posted on 2024-01-31

187 Casein kinase 1 controls components of a TORC2 signaling network in budding yeast

Lucena, R.; Jasani, A.; Anastasia, S.; Kellogg, D.; Gavilan, M. A.

10.1101/2024.01.30.578072 — cell biology — Posted on 2024-01-31

188 Trypanosoma brucei ultra-structure cell modifications caused by knockdown of the ribonuclease Rrp44/Dis3

Cesaro, G.; Hiraiwa, P. M.; Carneiro, F. R. G.; Rouam, V.; Legrand, P.; Conesa, J. J.; Refregiers, M.; Pereiro, E.; Guimaraes, B. G.; Jamme, F.; Zanchin, N. I. T.

10.1101/2020.02.29.971424 — cell biology — Posted on 2024-01-31

189 Auditory stimuli extend the temporal window of visual integration by modulating alpha-band oscillations

Xu, M.; Han, B.; Chen, Q.; Shen, L.

10.1101/2024.01.31.578121 — neuroscience — Posted on 2024-01-31

190 Charting the Spatial Transcriptome of the Human Cerebral Cortex at Single-Cell Resolution

Wei, S.; Luo, M.; Chen, R.; Wang, P.; Jin, X.; Xu, C.; Lin, X.; Xu, Z.; Liu, H.; Huang, P.; Xu, J.; Jiang, Q.

10.1101/2024.01.31.576150 — neuroscience — Posted on 2024-01-31

191 Distinguishing cophylogenetic signal from phylogenetic congruence clarifies the interplay between evolutionary history and species interactions

Perez-Lamarque, B.; Morlon, H.

10.1101/2023.07.21.550001 — evolutionary biology — Posted on 2024-01-31

192 Soil intake modifies the gut microbiota and alleviates ovalbumin-induced mice asthma inflammation

Li, M.; Li, N.; Dong, Y.; Zhang, H.; Bai, Z.; Zhang, R.; Fei, Z.; Zhu, W.; Xiao, P.; Xiao, S.; Zhou, D.

10.1101/2023.05.31.543010 — microbiology — Posted on 2024-01-31

193 Identification and characterization of a potentially novel dorsal cutaneous muscle in rodents

Petruska, J. C.

10.1101/2024.01.30.577894 — neuroscience — Posted on 2024-01-31

194 A deep-learning strategy to identify cell types across species from high-density extracellular recordings

Beau, M.; Herzfeld, D. J.; Naveros, F.; Hemelt, M. E.; D'Agostino, F.; Oostland, M.; Sanchez-Lopez, A.; Chung, Y. Y.; Maibach, M.; Stabb, H. N.; Martinez Lopera, M. G.; Lajko, A.; Zedler, M.; Ohmae, S.; Hall, N. J.; Clark, B. A.; Cohen, D.; Lisberger, S. G.; Kostadinov, D.; Hull, C.; Häusser, M.; Medina, J. F.

10.1101/2024.01.30.577845 — neuroscience — Posted on 2024-01-31

195 Widespread latent hyperactivity of nociceptors outlasts enhanced avoidance behavior following incision injury

Bavencoffe, A. G.; Lopez, E. R.; Johnson, K. N.; Tian, J.; Gorgun, F. M.; Shen, B. Q.; Zhu, M. X.; Dessauer, C. W.; Walters, E. T.

10.1101/2024.01.30.578108 — neuroscience — Posted on 2024-01-31

196 Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924

Lepine, S.; Maussion, G.; Schneider, A.; Nauleau-Javaudin, A.; Castellanos-Montiel, M. J.; Jimenez Ambriz, G.; Spiegelman, D.; Abdian, N.; Franco-Flores, A. K.; Haghi, G.; Gursu, L.; Chaineau, M.; Durcan, T.

10.1101/2024.01.30.578100 — neuroscience — Posted on 2024-01-31

197 Metabolic resistance of Abeta3pE-42, epitope of the anti-Alzheimer therapeutic antibody, donanemab.

Saido, T. C.; Sasaguri, H.; Takamura, R.; Watamura, N.; Fujioka, R.; Yamazaki, N.; Sekiguchi, M.; Watanabe-Iwata, K.; Kamano, N.; Matsuba, Y.; Tsubuki, S.; Saito, T.; Iwata, N.; Higuchi, M.; Mann, D.; Robinson, A. c.

10.1101/2024.01.30.578111 — neuroscience — Posted on 2024-01-31

198 Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana

Charura, N.; Llamas, E.; De Quattro, C.; Vilchez, D.; Nowack, M. K.; Zuccaro, A.

10.1101/2023.02.03.526420 — plant biology — Posted on 2024-01-31

199 DeepGOMeta: Predicting functions for microbes

Tawfiq, R.; Niu, K.; Hoehndorf, R.; Kulmanov, M.

10.1101/2024.01.28.577602 — bioinformatics — Posted on 2024-01-31

200 The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

Bohl, V.; Hollmann, N. M.; Melzer, T.; Katikaridis, P.; Meins, L.; Simon, B.; Flemming, D.; Sinning, I.; Hennig, J.; Mogk, A.

10.1101/2023.10.08.561430 — biochemistry — Posted on 2024-01-31

201 Variation in Neural Crest Development and Functional Divergence of sox10 Paralogs Contribute to Morphological Diversification in Cichlid Fishes

Marconi, A.; Vernaz, G.; Karunaratna, A.; Ngochera, M. J.; Durbin, R.; Santos, M. E.

10.1101/2024.01.30.578004 — evolutionary biology — Posted on 2024-01-31

202 The role of gene duplication in facilitating divergent patterns of gene expression across a complex life cycle

DuBose, J. G.; de Roode, J. C.

10.1101/2024.01.30.577993 — evolutionary biology — Posted on 2024-01-31

203 On the impact of re-mating and residual fertility on the Sterile Insect Technique efficacy: case study with the medfly, Ceratitis capitata

DUMONT, Y.; OLIVA, C. F.

10.1101/2023.08.17.552275 — ecology — Posted on 2024-01-31

204 The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links

Altshuller, M.; He, X.; MacKrell, E. J.; Wernke, K. M.; Wang, J. W. H.; Selles-Baiget, S.; Wang, T.-Y.; Chou, T.-F.; Duxin, J. P.; Balskus, E. P.; Herzon, S. B.; Semlow, D.

10.1101/2024.01.30.576698 — molecular biology — Posted on 2024-01-31

205 Peripheral serotonergic neurons regulate gut motility and anxiety-like behavior

Zhang, H.; Leitner, D.; Hasegawa, Y.; Waldor, M. K.

10.1101/2023.05.12.540588 — neuroscience — Posted on 2024-01-30

206 ODL-BCI: Optimal deep learning model for brain-computer interface to classify students confusion via hyperparameter tuning

Miah, M. O.; Habiba, U.; Kabir, M. F.

10.1101/2023.10.30.564829 — neuroscience — Posted on 2024-01-31

207 Single-Cell RNA-seq based elucidation of the antidepressant hyperforin biosynthesis de novo in St. John's wort.

Wu, S.; Morotti, A. L. M.; Yang, J.; Wang, E.; Tatsis, E. C.

10.1101/2024.01.24.577018 — plant biology — Posted on 2024-01-31

208 A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data

Vinceti, A.; Iannuzzi, R. M.; Trastulla, L.; Iorio, F.

10.1101/2024.01.30.577980 — bioinformatics — Posted on 2024-01-31

209 Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells

Dehghannasiri, R.; Henderson, G.; Bierman, R.; Chaung, K.; Baharav, T. Z.; Wang, P. L.; Salzman, J.

10.1101/2022.12.06.519414 — bioinformatics — Posted on 2024-01-30

210 Induction of NASH in the Nwd1-/- mouse liver via SERCA2-dependent endoplasmic reticulum stress

Yamada, S.; Nakadate, K.; Mizukoshi, T.; Kawakami, K.; Kobayashi, R.; Horii, T.; Hatada, I.; Sakakibara, S.-i.

10.1101/2024.01.26.577307 — molecular biology — Posted on 2024-01-30

211 Microbial community organization during anaerobic pulp and paper mill wastewater treatment

Meyer, T.; Yang, M. I.; Nesbo, C.; Master, E.; Edwards, E. A.

10.1101/2023.08.11.553022 — microbiology — Posted on 2024-01-30

212 Pain reflects the informational value of nociceptive inputs.

Coll, M.-P.; Walden, Z.; Bourgoin, P.-A.; Taylor, V.; Rainville, P.; Robert, M.; Nguyen, D. K.; Jolicoeur, P.; Roy, M.

10.1101/2023.07.14.549006 — neuroscience — Posted on 2024-01-30

213 Both mOTS-words and pOTS-words prefer emoji stimuli over text stimuli during a reading task

Dalski, A.; Kular, H.; Jorgensen, J. G.; Grill-Spector, K.; Grotheer, M.

10.1101/2023.11.07.565794 — neuroscience — Posted on 2024-01-30

214 Simplest Model of Nervous System. II. Evolutionary Optimization

Sinitskiy, A. V.

10.1101/2023.11.24.568590 — biophysics — Posted on 2024-01-30

215 Multiple variants of the type VII secretion system in Gram-positive bacteria

Garrett, S. R.; Higginson, A. B.; Palmer, T.

10.1101/2024.01.30.577966 — microbiology — Posted on 2024-01-30

216 LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Brain Organoids

Costa, M. d. N.; Goto-Silva, L.; Nascimento, J. M.; Domith, I.; Karmirian, K.; Feilding, A.; Trindade, P.; Martins-de-Souza, D.; Rehen, S. K.

10.1101/2024.01.30.577659 — neuroscience — Posted on 2024-01-30

217 Cortical multi-area model with joint excitatory-inhibitory clusters accounts for spiking statistics, inter-area propagation, and variability dynamics

Pronold, J.; Morales-Gregorio, A.; Rostami, V.; van Albada, S. J.

10.1101/2024.01.30.577979 — neuroscience — Posted on 2024-01-30

218 Scale-Dependent Coding of the Hippocampus in Relational Memory

Ding, W.; Lin, Y.; Zhang, B.; Liu, J.

10.1101/2024.01.29.577883 — neuroscience — Posted on 2024-01-30

219 SuperCellCyto: enabling efficient analysis of large scale cytometry datasets

Putri, G. H.; Howitt, G.; Marsh-Wakefield, F.; Ashhurst, T. M.; Phipson, B.

10.1101/2023.08.14.553168 — bioinformatics — Posted on 2024-01-30

220 Variational Bayesian Phylogenies through Matrix Representation of Tree Space

Bouckaert, R.

10.1101/2023.10.19.563180 — bioinformatics — Posted on 2024-01-30

221 Harnessing the regenerative potential of interleukin11 to enhance heart repair

Shin, K.; Rodriguez-Parks, A.; Xia, Y.; Dong, C.; Kelles, S.; Cao, J.; Kang, J.

10.1101/2024.01.29.577788 — developmental biology — Posted on 2024-01-30

222 Soma-to-germline BMP signal is essential for Drosophila spermiogenesis

Beard, E. K.; Norris, R. P.; Furusho, M.; Terasaki, M.; Inaba, M.

10.1101/2024.01.30.578090 — developmental biology — Posted on 2024-01-30

223 Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

CHANG, J.; PICKARD, A.; Herrera, J. A.; O'Keefe, S.; Hartshorn, M.; GARVA, R.; Hoyle, A.; Dingle, L.; Zeltz, C.; Wong, J.; Reid, A.; Venkateswaran, R. V.; Lu, Y.; Caswell, P.; High, S.; Gullberg, D.; KADLER, K. E.

10.1101/2021.03.25.436925 — cell biology — Posted on 2024-01-30

224 Reduced Telomerase Interaction with Telomeres Alters Meiotic Chromosome Motion and Gamete Viability

Smith, D. L.; Oke, A.; Pollard, M.; Anderson, C. M.; Zhuge, T.; Yam, P.; Gromova, T.; Conant, K.; Chu, D.; Patel, N.; Gonzalez, F.; Stoddard, C.; Burgess, S. M.; Hochwagen, A.; Marshall, W. F.; Blackburn, E.; Fung, J. C.

10.1101/654376 — cell biology — Posted on 2024-01-30

225 Single-cell Rapid Capture Hybridization sequencing (scRaCH-seq) to reliably detect isoform usage and coding mutations in targeted genes at a single-cell level

Peng, H.; Jabbari, J. S.; Tian, L.; Chua, C. C.; Anstee, N. S.; Amin, N.; Wei, A. H.; Davidson, N. M.; Roberts, A. W.; Huang, D. C. S.; Ritchie, M. E.; Thijssen, R.

10.1101/2024.01.30.577942 — molecular biology — Posted on 2024-01-30

226 Rewriting endogenous human transcripts with trans-splicing

Chandrasekaran, S. S.; Tau, C.; Nemeth, M.; Pawluk, A.; Konermann, S.; Hsu, P. D.

10.1101/2024.01.29.577779 — molecular biology — Posted on 2024-01-30

227 The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links

Altshuller, M.; He, X.; MacKrell, E. J.; Wernke, K. M.; Wang, J. W. H.; Selles-Baiget, S.; Wang, T.-Y.; Chou, T.-F.; Duxin, J. P.; Balskus, E. P.; Herzon, S. B.; Semlow, D.

10.1101/2024.01.30.576698 — molecular biology — Posted on 2024-01-30

228 SCF FBXL5 ubiquitin ligase regulates stability of von-Hippel Lindau protein and the HIF1α-dependent response to hypoxia

Wohlschlegel, J.; Mayank, A. K.; Pandey, V.; Li, L.; Jami-Alahmadi, Y.; Lien, K.; Kassem, A. M.

10.1101/2024.01.29.577840 — molecular biology — Posted on 2024-01-30

229 Intratumoral Microbiome of Adenoid Cystic Carcinomas and Comparison with other Head and Neck Cancers

Karpinets, T.; Mitani, Y.; Chang, C.-C.; Wu, X.; Song, X.; Flores, I. I.; McDaniel, L. K.; Hoballah, Y. M.; Veguilla, F. J.; Ferrarotto, R.; Colbert, L.; Ajami, N.; Jenq, R.; Zhang, J.; Futreal, A.; El-Naggar, A.

10.1101/2024.01.30.578054 — microbiology — Posted on 2024-01-30

230 Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity

Acosta Zaldivar, M.; Qi, W.; Mishra, A.; Roy, U.; King, W. R.; Patton-Vogt, J.; Anderson, M. Z.; Kohler, J. R.

10.1101/2024.01.29.577887 — microbiology — Posted on 2024-01-30

231 gcplyr: an R package for microbial growth curve data analysis

Blazanin, M.

10.1101/2023.04.30.538883 — microbiology — Posted on 2024-01-30

232 SAR324 and related lineages are associated with the evolutionary history and origins of dsr-mediated sulfur oxidation

Klier, K. M.; Martin, C.; Langwig, M. V.; Anantharaman, K.

10.1101/2024.01.30.576480 — microbiology — Posted on 2024-01-30

233 Arc mediates intercellular synaptic plasticity via IRSp53-dependent extracellular vesicle biogenesis.

Ravens, A.; Sullivan, K.; Einstein, J.; Keceli, S. K.; Kicmal, T.; Tyagi, M.; Hantak, M. P.; Shepherd, T.; Stewart, A.; Lyon, K.; Dharan, A.; Gallagher, T.; Campbell, E. M.; Shepherd, J. D.

10.1101/2024.01.30.578027 — neuroscience — Posted on 2024-01-30

234 Urolithin A improves Alzheimers disease cognition and restores mitophagy and lysosomal functions

Hou, Y.; Chu, X.; Park, J.-H.; Zhu, Q.; HUssein, M.; Li, Z.; Madsen, H. B.; Yang, B.; Wei, Y.; Wang, Y.; Fang, E.; Croteau, D.; Bohr, V. A.

10.1101/2024.01.30.577986 — neuroscience — Posted on 2024-01-30

235 Macrophages protect against sensory axon degeneration in diabetic neuropathy

Hakim, S.; Jain, A.; Petrova, V.; Indajang, J.; Kawaguchi, R.; Wang, Q.; Duran, E. S.; Nelson, D.; Adamson, S. S.; Greene, C. A.; Woolf, C. J.

10.1101/2024.01.30.577801 — neuroscience — Posted on 2024-01-30

236 Revealing brain network dynamics during the emotional state of suspense using topological data analysis

Olave Herrera, A. A.; Perea, J. A.; Gomez, F.

10.1101/2024.01.29.577820 — neuroscience — Posted on 2024-01-30

237 Identifying a Distractor Produces Object-Based Inhibition in an Allocentric Reference Frame for Saccade Planning

Olenick, C. E.; Jordan, H.; Fallah, M.

10.1101/2024.01.30.578028 — neuroscience — Posted on 2024-01-30

238 Acute sleep deprivation reduces fear memories in male and female mice

Foilb, A. R.; Taylor-Yeremeeva, E. M.; Schmidt, B. D.; Ressler, K. J.; Carlezon, W. A.

10.1101/2024.01.30.577985 — neuroscience — Posted on 2024-01-30

239 The integration of tandem gene repeats via a bacterial type-II toxin-antitoxin-mediated gene amplification (ToxAmp) system and stability visualisation in Saccharomyces cerevisiae

Evans, S.; Lu, Z.; McDonnell, L.; Anderson, W.; Peralta, F.; Watkins, T.; Ahmed, H.; Luna-Flores, C. H.; Loan, T. D.; Navone, L.; Trau, M.; Scott, C.; Speight, R.; Vickers, C.; Peng, B.

10.1101/2024.01.30.578080 — synthetic biology — Posted on 2024-01-30

240 AC-BioSD : A biomolecular signal differentiator module with enhanced performance

Alexis, E.; Avalos, J. L.; Cardelli, L.; Papachristodoulou, A.

10.1101/2024.01.29.577841 — synthetic biology — Posted on 2024-01-30

241 A framework for reconstructing ancient food webs using functional trait data

Shaw, J. O.; Dunhill, A. M.; Beckerman, A. P.; Dunne, J. A.; Hull, P. M.

10.1101/2024.01.30.578036 — paleontology — Posted on 2024-01-30

242 The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins.

Körner, C.; Schäfer, J.-H.; Esch, B. M.; Parey, K.; Walter, S.; Teis, D.; Januliene, D.; Schmidt, O.; Moeller, A.; Fröhlich, F.

10.1101/2024.01.30.577963 — biochemistry — Posted on 2024-01-30

243 GMMA can stabilize proteins across different functional constraints

Daffern, N.; Johansson, K. E.; Baumer, Z.; Delbert-Robertson, N.; Woojuh, J.; Bedewitz, M. A.; Davis, Z.; Wheeldon, I.; Cutler, S.; Lindorff-Larsen, K. A.; Whitehead, T. A.

10.1101/2024.01.30.577994 — biochemistry — Posted on 2024-01-30

244 Synthesis and application of a photocaged L-lactate

Miyazaki, I.; Tsao, K. K.; Kamijo, Y.; Nasu, Y.; Terai, T.; Campbell, R. E.

10.1101/2024.01.30.577898 — biochemistry — Posted on 2024-01-30

245 Can we trace the social affiliation of rooks (Corvusfrugilegus) through their vocal signature?

Martin, K.; Cornero, F. M.; Danby, E.; Daunay, V.; Nervet, L.; Clayton, N. S.; Obin, N.; Dufour, V.

10.1101/2024.01.30.577907 — animal behavior and cognition — Posted on 2024-01-30

246 Bold zebrafish (danio rerio) learn faster in an associative learning task

Corcoran, J.; Storks, L.; Wong, R. Y.

10.1101/2024.01.30.578005 — animal behavior and cognition — Posted on 2024-01-30

247 Intolerance of uncertainty does not significantly predict decisions about delayed, probabilistic rewards

Cobos Cano, P. L.; Quintero Felipe, M. J.; Lopez Gutierrez, F. J.; Luque Ruiz, D.; Ciria Perez, L. F.; Moris Fernandez, J.

10.1101/2024.01.29.577520 — animal behavior and cognition — Posted on 2024-01-30

248 Etiology of Craniofacial and Cardiac Malformations in a Mouse Model of SF3B4-Related Syndromes

Kumar, S.; Bareke, E.; Lee, J.; Carlson, E.; Merkuri, F.; Schwager, E. E.; Maglio, S.; Fish, J. L.; Majewski, J.; Jerome-Majewska, L. A.

10.1101/2024.01.30.578039 — developmental biology — Posted on 2024-01-30

249 A feather star is born: embryonic development and nervous system organization in the crinoid Antedon mediterranea

Mercurio, S.; Gattoni, G.; Scari, G.; Ascagni, M.; Barzaghi, B.; Elphick, M. R.; Benito-Gutierrez, E.; Pennati, R.

10.1101/2024.01.30.577964 — developmental biology — Posted on 2024-01-30

250 Hepatoblast iterative apicobasal polarization is regulated by extracellular matrix remodeling

Delpierre, J.; Valenzuela, J. I.; Bovyn, M.; Martins, N. P.; Belicova, L.; Repnik, U.; Bebelman, M.; Seifert, S.; Haas, P. A.; Kalaidzidis, Y. L.; Zerial, M.

10.1101/2024.01.30.578046 — developmental biology — Posted on 2024-01-30

251 PCP Auto Count: A Novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting

Stansak, K. L.; Baum, L. D.; Ghosh, S.; Thapa, P.; Vanga, V.; Walters, B. J.

10.1101/2024.01.30.578047 — developmental biology — Posted on 2024-01-30

252 Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells

Lazarchuk, P.; Nguyen, M. M.; Curca, C. M.; Pavlova, M. N.; Oshima, J.; Sidorova, J. M. M.

10.1101/2024.01.29.577850 — molecular biology — Posted on 2024-01-30

253 Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohns Disease

Jurickova, I.; Dreskin, B.; Angerman, E.; Bonkowski, E.; Tominaga, K.; Iwasawa, K.; Braun, T.; Takebe, T.; Helmrath, M.; Haberman, Y.; Wells, J.; Denson, L.

10.1101/2024.01.30.577959 — molecular biology — Posted on 2024-01-30

254 An LPS-dephosphorylating alkaline phosphatase of PhoA family from the marine bacterium Cobetia amphilecti KMM 296 and multiplicity of alkaline phosphatase families in Cobetia spp.

Balabanova, L. A.; Bakholdina, S.; Buinovskaya, N.; Noskova, Y.; Seitkalieva, A.; Vlasova, V.; Bondarev, G.; Son, O.; Kolpakova, O.

10.1101/2024.01.29.577745 — molecular biology — Posted on 2024-01-30

255 tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development

Rappol, T.; Waldl, M.; Chugunova, A.; Hofacker, I. L.; Pauli, A.; Vilardo, E.

10.1101/2024.01.30.575011 — molecular biology — Posted on 2024-01-30

256 Uniquome: Construction and Decoding of a Novel Proteomic Atlas that Contains New Peptide Entities

Kontopodis, E.; Pierros, V.; Vorgias, C.; Papassideri, I.; Stravopodis, D. J.; Tsangaris, G. T.

10.1101/2024.01.30.577925 — molecular biology — Posted on 2024-01-30

257 LncRNA GAS6-AS1 contributes to 5-fluorouracil resistance in colorectal cancer

Zhu, Z.; Li, M.; Weng, J.; Li, S.; Guo, T.; Guo, Y.; Xu, Y.

10.1101/2024.01.30.577984 — molecular biology — Posted on 2024-01-30

258 Metagenomic Insights Reveal Unrecognized Diversity of Entotheonella in Japanese Theonella Sponges

Yamabe, S.; Yoshitake, K.; Ninomiya, A.; Piel, J.; Takeyama, H.; Matsunaga, S.; Takada, K.

10.1101/2024.01.29.577764 — microbiology — Posted on 2024-01-30

259 Fluorinated trehalose analogues for cell surface engineering and imaging of Mycobacterium tuberculosis

Guy, C. S.; Gott, J. A.; Ramirez-Cardenas, J.; de Wolf, C.; Furze, C. M.; West, G.; Munoz-Garcia, J. C.; Angulo, J.; Fullam, E.

10.1101/2024.01.30.577379 — microbiology — Posted on 2024-01-30

260 Disrupting Homologous Recombination or Single-Strand Annealing Significantly Hinders CRISPR-Cas12a-Assisted Nonhomologous End-Joining Gene Editing Efficiency in Mycobacterium abscessus

Zeng, S.; Ju, Y.; Alam, M. S.; Lu, Z.; Hameed, H. M. A.; Li, L.; Tian, X.; Fang, C.; Fang, X.; Ding, J.; Wang, X.; Hu, J.; Wang, S.; Zhang, T.

10.1101/2024.01.29.577284 — microbiology — Posted on 2024-01-30

261 New antiviral defences are genetically embedded within prokaryotic immune systems.

Payne, L. J.; Hughes, T. C. D.; Fineran, P. C.; Jackson, S. A.

10.1101/2024.01.29.577857 — microbiology — Posted on 2024-01-30

262 Detailing organelle division and segregation in Plasmodium falciparum

Verhoef, J. M. J.; Boshoven, C.; Evers, F.; Akkerman, L. J.; Gijsbrechts, B. C. A.; van de Vegte-Bolmer, M.; van Gemert, G.-J.; Vaidya, A. B.; Kooij, T. W. A.

10.1101/2024.01.30.577899 — microbiology — Posted on 2024-01-30

263 The usefulness of Nanopore Sequencing in Whole-Genome Sequencing-Based Genotyping of Listeria monocytogenes and Salmonella enterica serovar Enteritidis

Hong, Y.-P.; Chen, B.-H.; Wang, Y.-W.; Teng, R.-H.; Wei, H. L.; Chiou, C.-S.

10.1101/2024.01.29.577746 — microbiology — Posted on 2024-01-30

264 Evaluation of behavioral and neurochemical changes induced by carbofuran in zebrafish (Danio rerio)

Oliveira, G. R.; Gallas-Lopes, M.; Chitolina, R.; Bastos, L. M.; Portela, S. M.; Stahlhofer-Buss, T.; Gusso, D.; Gomez, R.; Wyse, A. T.; Herrmann, A. P.; Piato, A.

10.1101/2024.01.30.578041 — neuroscience — Posted on 2024-01-30

265 The human claustrum tracks slow waves during sleep

Lamsam, L.; Liang, M.; Gu, B.; Sun, G.; Hirsch, L. J.; Pittenger, C.; Kaye, A. P.; Krystal, J. H.; Damisah, E.

10.1101/2024.01.29.577851 — neuroscience — Posted on 2024-01-30

266 The Primate Cortical LFP Exhibits Multiple Spectral and Temporal Gradients and Widespread Task-Dependence During Visual Short-Term Memory

Hoffman, S. J.; Dotson, N. M.; Lima, V.; Gray, C. M.

10.1101/2024.01.29.577843 — neuroscience — Posted on 2024-01-30

267 Slow running benefits: Boosts in mood and facilitation of prefrontal cognition even at very light intensity

Damrongthai, C.; Kuwamizu, R.; Yamazaki, Y.; Aoike, N.; Lee, D.; Byun, K.; Torma, F.; Churdchomjan, W.; Yassa, M. A.; Adachi, K.; Soya, H.

10.1101/2024.01.29.575971 — neuroscience — Posted on 2024-01-30

268 Examining motor evidence for the pause-then-cancel model of action-stopping: Insights from motor system physiology

Tatz, J. R.; Carlson, M. O.; Lovig, C.; Wessel, J. R.

10.1101/2024.01.30.577976 — neuroscience — Posted on 2024-01-30

269 Supervised deep machine learning models predict forelimb movement from excitatory neuronal ensembles and suggest distinct pattern of activity in CFA and RFA networks

Latifi, S.; Carmichael, S. T.

10.1101/2024.01.30.577967 — neuroscience — Posted on 2024-01-30

270 Systemic inflammation triggers long-lasting neuroinflammation and accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein

Massaro Cenere, M.; Tiberi, M.; Paldino, E.; D'Addario, S. L.; Federici, M.; Giacomet, C.; Cutuli, D.; Matteocci, A.; Cossa, F.; Zarrilli, B.; Ledonne, A.; Petrosini, L.; Berretta, N.; Fusco, F. R.; Chiurchiu, V.; Mercuri, N. B.

10.1101/2024.01.30.577912 — neuroscience — Posted on 2024-01-30

271 PREFRONTAL CORRELATES OF FEAR GENERALIZATION DURING ENDOCANNABINOID DEPLETION

Rosas-Vidal, L. E.; Naskar, S.; Mayo, L. M.; Perini, I.; Altemus, M.; Engelbrektsson, H.; Jagasia, P.; Heilig, M.; Patel, S.

10.1101/2024.01.30.577847 — neuroscience — Posted on 2024-01-30

272 A spinal cord injury time and severity consensus transcriptomic reference suite in rat reveals translationally-relevant biomarker genes

Grillo-Risco, R.; Hidalgo, M. R.; Martinez-Rojas, B.; Moreno-Manzano, V.; Garcia-Garcia, F.

10.1101/2024.01.30.578030 — neuroscience — Posted on 2024-01-30

273 CRISPR-Enabled Autonomous Transposable Element (CREATE) for RNA-based gene editing and delivery

Wang, Y.; Lin, R.-Z.; Harris, M.; Lavayen, B.; Mccreedy, B.; Getts, D.

10.1101/2024.01.29.577809 — synthetic biology — Posted on 2024-01-30

274 From small to tall: breed-varied household pet dogs can be trained to detect Parkinson's Disease

Holt, L.; Johnston, S. V.

10.1101/2024.01.29.577858 — animal behavior and cognition — Posted on 2024-01-30

275 MacAction: Realistic 3D macaque body animation based on multi-camera markerless motion capture

Martini, L. M.; Bognar, A.; Vogels, R.; Giese, M. A.

10.1101/2024.01.29.577734 — animal behavior and cognition — Posted on 2024-01-30

276 Behavioral state influences encoding mechanisms of color and odor integration in a model insect, the bumblebee Bombus impatiens.

Graver, K.; Sommer, J.; Rao, V.; Tafuri, G.; Sprayberry, J. D.

10.1101/2024.01.30.577961 — animal behavior and cognition — Posted on 2024-01-30

277 Tapeworm infection affects sleep behavior in three-spined stickleback

Bauhus, M. B.; Mews, S.; Kurtz, J.; Brinker, A.; Peuss, R.; Anaya-Rojas, J. M.

10.1101/2024.01.30.577962 — animal behavior and cognition — Posted on 2024-01-30

278 miR-26 deficiency causes alterations in lens transcriptome and results in adult-onset cataract

Upreti, A.; Hoang, T. V.; Li, M.; Tangeman, J. A.; Dierker, D. S.; Wagner, B. D.; Tsonis, P. A.; Liang, C.; Lachke, S. A.; Robinson, M. L.

10.1101/2024.01.29.577818 — developmental biology — Posted on 2024-01-30

279 Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through multiple mechanisms

Liu, P.; Yue, C.; Meng, B.; Xiao, T.; Yang, S.; Liu, S.; Jian, F.; Zhu, Q.; Yu, Y.; Ren, Y.; Wang, P.; Li, Y.; Wang, J.; Mao, X.; Shao, F.; Wang, Y.; Gupta, R. K.; Cao, Y.; Wang, X.

10.1101/2024.01.29.577677 — microbiology — Posted on 2024-01-30

280 Identification of novel origins of transfer across bacterial plasmids

Ares-Arroyo, M.; Nucci, A.; Rocha, E. P. C.

10.1101/2024.01.30.577996 — microbiology — Posted on 2024-01-30

281 Exploiting Bacterial Effector Proteins to Uncover Evolutionarily Conserved Antiviral Host Machinery

Embry, A.; Baggett, N. S.; Heisler, D. B.; White, A.; de Jong, M. F.; Kocsis, B. L.; Tomchick, D. R.; Alto, N. M.; Gammon, D.

10.1101/2024.01.29.577891 — microbiology — Posted on 2024-01-30

282 Putrescine acts as a signaling metabolite in the transition from nodulation to nitrogen fixation in Rhizobium phaseoli

Hernandez-Benitez, E. M.; Martinez-Romero, E.; Aguirre-Noyola, J. L.; Ledezma-Tejeida, D.

10.1101/2024.01.29.577838 — microbiology — Posted on 2024-01-30

283 The sense of agency from active causal inference

Chang, A. Y.-C.; Oi, H.; Maeda, T.; Wen, W.

10.1101/2024.01.29.577723 — neuroscience — Posted on 2024-01-30

Vergani, A. A.; Mazzeo, S.; Moschini, V.; Burali, R.; Lassi, M.; Amato, L. G.; Carpaneto, J.; Salvestrini, G.; Fabbiani, C.; Giacomucci, G.; Morinelli, C.; Emiliani, F.; Scarpino, M.; Bagnoli, S.; Ingannato, A.; Nacmias, B.; Padiglioni, S.; Sorbi, S.; Bessi, V.; Grippo, A.; Mazzoni, A.

10.1101/2024.01.30.577910 — neuroscience — Posted on 2024-01-30

285 Endocannabinoid-mediated rescue of somatosensory cortex activity, plasticity and related behaviors following an early in life concussion.

Badaut, J.; Hippauf, L.; Malinconi, M.; Noarbe, B. P.; Obenaus, A.; Dubois, C. J.

10.1101/2024.01.30.577914 — neuroscience — Posted on 2024-01-30

286 Stimulating the medial prefrontal cortex disrupts inhibitory control over memory by modulating frontal and parietal brain regions

Khan, A.; Ti, C. H. E.; Yuan, K.; Garcia, M. C.; Anderson, M.; Tong, R. K.-Y.

10.1101/2024.01.30.577598 — neuroscience — Posted on 2024-01-30

287 Identifying the function of the NMDA NR1C2 subunit through its interaction with Magi-2 during inflammatory pain

Sheehan, G. D.; Martin, M.; Roszczyk, A.; Hao, K.; Bhattacharjee, A.

10.1101/2024.01.30.578033 — neuroscience — Posted on 2024-01-30

288 Distributed fMRI dynamics predict distinct EEG rhythms across sleep and wakefulness

Jacob, L. P. L.; Bailes, S. M.; Williams, S. D.; Stringer, C.; Lewis, L. D.

10.1101/2024.01.29.577429 — neuroscience — Posted on 2024-01-30

289 Synaptic motility and functional stability in the whisker cortex

Sherf, N.; Shamir, M.

10.1101/2024.01.28.577661 — biophysics — Posted on 2024-01-30

290 Invariant crossmodal equivalence evokes visual imagery from sounds in rhesus monkeys

Cabrera-Ruiz, E.; Alva, M.; Mata, M.; Trevino, M.; Vergara, J.; Figueroa, T.; Perez-Orive, J.; Lemus, L.

10.1101/2024.01.05.574397 — animal behavior and cognition — Posted on 2024-01-30

291 Mitotic chromosomes are self-entangled and disentangle through a Topoisomerase II-dependent two stage exit from mitosis

Hildebrand, E. M.; Polovnikov, K.; Dekker, B.; Liu, Y.; Lafontaine, D. L.; Fox, A. N.; Li, Y.; Venev, S. V.; Mirny, L. A.; Dekker, J.

10.1101/2022.10.15.511838 — genomics — Posted on 2024-01-30

292 Sexually discordant selection is associated with trait specific morphological changes and a complex genomic response

Audet, T.; Krol, J.; Pelletier, K.; Stewart, A. D.; Dworkin, I.

10.1101/2023.08.31.555745 — evolutionary biology — Posted on 2024-01-30

293 Oviposition status and sugar availability influence measures of transmission potential in malaria-infected mosquitoes.

Shiau, J. C.; Garcia-Diaz, N.; Kyle, D. E.; Pathak, A.

10.1101/2024.01.25.577126 — microbiology — Posted on 2024-01-30

294 Modulation of locomotion and motor neuron response by the cohesive effect of acute and chronic feeding states and acute d-amphetamine treatment in zebrafish larvae.

Bansal, P.; Roitman, M. F.; Jung, E. E.

10.1101/2024.01.28.577634 — neuroscience — Posted on 2024-01-30

295 Diffusion MRS tracks distinct trajectories of neuronal development in the cerebellum and thalamus of rat neonates.

Ligneul, C.; Qiu, L.; Clarke, W. T.; Jbabdi, S.; Palombo, M.; Lerch, J.

10.1101/2023.10.16.562599 — neuroscience — Posted on 2024-01-30

296 BDNF signaling requires Matrix Metalloproteinase-9 during structural synaptic plasticity

Legutko, D.; Kuzniewska, B.; Kalita, K.; Yasuda, R.; Kaczmarek, L.; Michaluk, P.

10.1101/2023.12.08.569797 — neuroscience — Posted on 2024-01-30

297 Induction of common bean OVATE Family Protein 7 (PvOFP7) promotes resistance to common bacterial blight

Gaudin, C.; Preveaux, A.; Aubineau, N.; Le Goff, D.; Jacques, M.-A.; Chen, N. W. G.

10.1101/2024.01.26.577399 — plant biology — Posted on 2024-01-30

298 Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control

Chilloux, J.; Brial, F.; Everard, A.; Smyth, D.; Andrikopoulos, P.; Zhang, L.; Plovier, H.; Myridakis, A.; Hoyles, L.; Moreno-Navarrete, J. M.; Luque, J. L.; Casagrande, V.; Menghini, R.; Ahmetaj-Shala, B.; Blancher, C.; Martinez-Gili, L.; Gencer, S.; Fearnside, J. F.; Barton, R. H.; Neves, A. L.; Rothwell, A. R.; Gerard, C.; Calderari, S.; Williamson, M. J.; Fuchs, J. E.; Govada, L.; Boulange, C. L.; Patel, S.; Scott, J.; Thursz, M.; Chayen, N.; Glen, R. C.; Gooderham, N. J.; Nicholson, J. K.; Federici, M.; Fernandez-Real, J. M.; Gauguier, D.; Liu, P. P.; Cani, P. D.; Dumas, M.-E. E.

10.1101/277434 — physiology — Posted on 2024-01-30

299 Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth

Johnson, S. S.; Liu, D.; Ewald, J. T.; Robles-Planells, C.; Christiansen, K. A.; Bayanbold, K.; Wels, B. R.; Solst, S. R.; ODorisio, M. S.; Allen, B. G.; Menda, Y.; Spitz, D. R.; Fath, M.

10.1101/2023.05.07.539772 — cancer biology — Posted on 2024-01-30

300 Transcriptional and phenotypic heterogeneity underpinning venetoclax resistance in AML

Mohanty, V.; Baran, N.; Huang, Y.; Ramage, C. L.; Cooper, L. M.; He, S.; Iqbal, R.; Daher, M.; CTD2 Research Network, ; Tyner, J. W.; Mills, G. B.; Konopleva, M.; Chen, K.

10.1101/2024.01.27.577579 — cancer biology — Posted on 2024-01-30

301 Revealing sphingolipids composition in extracellular vesicles and paternal β-cells after persistent hyperglycemia

Skalska, M.; Durak-Kozica, M.; Stepien, E. L.

10.1101/2024.01.06.574464 — biophysics — Posted on 2024-01-30

302 Harnessing AlphaFold to reveal state secrets: Prediction of hERG closed and inactivated states

Ngo, K.; Yarov-Yarovoy, V.; Clancy, C. E.; Vorobyov, I.

10.1101/2024.01.27.577468 — biophysics — Posted on 2024-01-30

303 Parameter-Efficient Fine-Tuning Enhances Adaptation of Single Cell Large Language Model for Cell Type Identification

He, F.; Fei, R.; Gao, M.; Su, L.; Zhang, X.; Xu, D.

10.1101/2024.01.27.577455 — bioinformatics — Posted on 2024-01-30

304 Comparative Analysis of Biomarkers in Type 2 Diabetes Patients with and without Comorbidities: Insights into the Role of Hypertension and Cardiovascular Disease

SAVVOPOULOS, S. V.; Hatzikirou, H.; Jelinek, H.

10.1101/2024.01.25.577186 — bioinformatics — Posted on 2024-01-30

305 Identification of anisotropy in chromosome dynamics by principal component analysis using integrated spatial genomics

Nara, T.; Takahashi, H.; Awazu, A.; Kikuchi, Y.

10.1101/2024.01.27.577362 — bioinformatics — Posted on 2024-01-30

306 Inference of Genomic Landscapes using Ordered Hidden Markov Models with Emission Densities (oHMMed)

Vogl, C.; Karapetiants, M.; Yildirim, B.; Kjartansdottir, H.; Kosiol, C.; Bergman, J.; Majka, M.; Mikula, L. C.

10.1101/2023.06.26.546495 — bioinformatics — Posted on 2024-01-30

307 Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery

Hanssen, F.; Garcia, M. U.; Folkersen, L.; Pedersen, A. S.; Lescai, F.; Jodoin, S.; Miller, E.; Seybold, M.; Wacker, O.; Smith, N.; nf-core community, ; Gabernet, G.; Nahnsen, S.

10.1101/2023.07.19.549462 — bioinformatics — Posted on 2024-01-30

308 Comparison between ribosomal assembly and machine learning tools for microbial identification of organisms with different characteristics

Chau, S.; Rojas, C.; Jetcheva, J.; Vijayakumar, S.; Yuan, S.; Stowbunenko, V.; Shelton, A. N.; Andreopoulos, W. B.

10.1101/2022.09.30.510284 — bioinformatics — Posted on 2024-01-30

309 nail: software for high-speed, high-sensitivity protein sequence annotation

Roddy, J. W.; Rich, D. H.; Wheeler, T. J.

10.1101/2024.01.27.577580 — bioinformatics — Posted on 2024-01-30

310 Aged Tendons Exhibit Altered Mechanisms of Strain-Dependent Extracellular Matrix Remodeling

Aggouras, A. N.; Stowe, E. J.; Mlawer, S. J.; Connizzo, B. K.

10.1101/2024.01.26.577397 — bioengineering — Posted on 2024-01-30

311 Structural basis of closed groove scrambling by a TMEM16 protein

Feng, Z.; Alvarenga, O. E.; Accardi, A.

10.1101/2023.08.11.553029 — biochemistry — Posted on 2024-01-30

312 The chromatin accessibility dynamics during cell fate specifications in zebrafish early embryogenesis

Xu, Q.; Zhang, Y.; Xu, W.; Liu, D.; Jin, W.; Chen, X.; Hong, N.

10.1101/2023.10.13.562312 — genomics — Posted on 2024-01-30

313 Chemotherapy activates inflammasomes to cause inflammation-associated bone loss

Wang, C.; Kaur, K.; Xu, C.; Abu-Amer, Y.; Mbalaviele, G.

10.1101/2023.10.06.561196 — cell biology — Posted on 2024-01-30

314 Ordered and disordered regions of the Origin Recognition Complex (ORC) combine to direct in-vivo binding at symmetric and non-symmetric motif sequences.

Chappleboim, M.; Naveh-Tassa, S.; Carmi, M.; Levy, Y.; Barkai, N.

10.1101/2024.01.27.577596 — cell biology — Posted on 2024-01-30

315 Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans

Otarigho, B.; Butts, A. F.; Aballay, A.

10.1101/2023.07.27.550570 — immunology — Posted on 2024-01-30

316 Brain-wide impacts of sedation on spontaneous activity and auditory processing in larval zebrafish

Favre-Bulle, I. A.; Muller, E.; Lee, C.; Scholz, L. A.; Arnold, J.; Munn, B.; Wainstein, G.; Shine, J. M.; Scott, E. K.

10.1101/2024.01.29.577877 — neuroscience — Posted on 2024-01-30

317 Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators

Masala, N.; Mittag, M.; Ambrad Giovannetti, E.; O'Neil, D. A.; Distler, F. J.; Rupprecht, P.; Helmchen, F.; Yuste, R.; Fuhrmann, M.; Beck, H.; Wenzel, M.; Kelly, T.

10.1101/2023.11.08.566169 — neuroscience — Posted on 2024-01-30

318 Pancreatic cancer mutationscape: revealing the link between modular restructuring and intervention efficacy amidst common mutations

Plaugher, D. R.; Murrugarra, D. R.

10.1101/2024.01.27.577546 — systems biology — Posted on 2024-01-30

319 Transcriptomic and epigenetic responses shed light on soybean resistance to Phytophthora sansomeana

Lee, G.; DiBiase, C. N.; Liu, B.; Li, T.; McCoy, A. G.; Chilvers, M. I.; Sun, L.; Wang, D.; Lin, F.; Zhao, M.

10.1101/2024.01.27.577583 — plant biology — Posted on 2024-01-30

320 On the role of urban tropical tree collections in carbon allocation: expanding their functions beyond cultural and biodiversity conservation

Salazar, E. E.; Villegas, J. C.; Ramirez, L. I. A.; Aristizabal, E. A. M.

10.1101/2024.01.28.577605 — plant biology — Posted on 2024-01-30

321 Self-incompatibility based functional genomics for rapid phenotypic characterization of seed metabolism genes

Azeez, A.; Bates, P. D.

10.1101/2024.01.26.577421 — plant biology — Posted on 2024-01-30

322 A general platform for targeting MHC-II antigens via a single loop

Du, H.; Liu, J.; Jude, K. M.; Yang, X.; Li, Y.; Bell, B.; Yang, H.; Kassardjian, A.; Mobedi, A.; Parekh, U.; Sperberg, A.; Julien, J.-P.; Mellins, E.; Garcia, K. C.; Huang, P.

10.1101/2024.01.26.577489 — bioengineering — Posted on 2024-01-30

323 Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens

Jiang, L.; Dalgarno, C.; Papalexi, E.; Mascio, I.; Wessels, H.-H.; Yun, H.; Iremadze, N.; Lithwick-Yanai, G.; Lipson, D.; Satija, R.

10.1101/2024.01.29.576933 — genomics — Posted on 2024-01-30

324 Quantifying microbial guilds

Rivas-Santisteban, J.; Yubero, P.; Robaina-Estevez, S.; Gonzalez, J. M.; Tamames, J.; Pedros-Alio, C.

10.1101/2023.07.23.550202 — ecology — Posted on 2024-01-30

325 Single-cell transcriptomics reveals colonic immune perturbations during amyloid-β driven Alzheimer's disease in mice

Makhijani, P.; Emani, R.; Aguirre, C. G.; Mu, W.-C.; Rane, A.; Ng, J. H. Y.; Valentino, T. R.; Manwaring-Mueller, M.; Tan, C. R.; Du, H.; Wu, F.; Khan, S.; Wilson, K. A.; Winer, S.; Wang, C.; Mortha, A.; Furman, D.; Ellerby, L. M.; Rojas, O. L.; Andersen, J. K.; Winer, D. A.

10.1101/2024.01.27.573841 — immunology — Posted on 2024-01-30

326 Adapting and optimizing GCaMP8f for use in C. elegans

Liu, J.; Bonnard, E.; Scholz, M.

10.1101/2024.01.29.577882 — neuroscience — Posted on 2024-01-30

327 Nutrient Abundance Signals the Changing of the Seasons by Phosphorylating PER2

Levine, D. C.; Reeh, R. H.; McMahon, T.; Mandrup-Poulsen, T.; Fu, Y.-H.; Ptacek, L. J.

10.1101/2024.01.29.577255 — neuroscience — Posted on 2024-01-30

328 Circadian coupling of mitochondria in a deep-diving mammal

Ciccone, C.; Kante, F.; Folkow, L. P.; Hazlerigg, D.; West, A. C.; Wood, S. H.

10.1101/2023.11.06.565796 — physiology — Posted on 2024-01-30

329 High total water loss driven by low-fat diet in desert-adapted mice

Blumstein, D. M.; Colella, J. P.; Linder, E.; MacManes, M. D.

10.1101/2022.04.15.488461 — physiology — Posted on 2024-01-30

330 Synthetic spider silk forming highly-aligned nanoarchitectures on 2D-material surfaces

Whittall, D. R.; Kato, R.; Okimura, A.; Takizawa, R.; Motai, K.; Maeda, H.; Yamazaki, Y.; Yano, T.-a.; Takano, E.; Hayamizu, Y.

10.1101/2024.01.27.577543 — biophysics — Posted on 2024-01-30

331 Scorpion α-toxin LqhαIT specifically interacts with a glycan at the pore domain of voltage-gated sodium channels

Phulera, S.; Dickson, C. J.; Schwalen, C. J.; Khoshouei, M.; Cassell, S. J.; Sun, Y.; Condos, T.; Whicher, J.; Weihofen, W. A.

10.1101/2024.01.26.577479 — biophysics — Posted on 2024-01-30

332 Deciphering the molecular mechanism of DNA-protein interactive co-condensates

Li, C.; Bian, Y.; Tang, Y.; Meng, L.; Yin, P.; Hong, Y.; Cheng, J.; Li, Y.; Lin, J.; Tang, C.; Chen, C.; Li, W.; Qi, Z.

10.1101/2024.01.26.577305 — biophysics — Posted on 2024-01-30

333 Comprehensive Hierarchical Classification of Transposable Elements based on Deep Learning

Qi, Y.; Chen, Y.; Wu, Y.; Li, Y.; Gao, M.; Zhang, F.; Liao, X.; Shang, X.

10.1101/2024.01.27.577599 — bioinformatics — Posted on 2024-01-30

334 DeepGOMeta: Predicting functions for microbes}

Hoehndorf, R.; Kulmanov, M.; Tawfiq, R.; Niu, K.

10.1101/2024.01.28.577602 — bioinformatics — Posted on 2024-01-30

335 reguloGPT: Harnessing GPT for Knowledge Graph Construction of Molecular Regulatory Pathways

Wu, X.; Zeng, Y.; Das, A.; Jo, S.; Zhang, T.; Patel, P.; Zhang, J.; Gao, S.-J.; Pratt, D.; Chiu, Y.-C.; Huang, Y.

10.1101/2024.01.27.577521 — bioinformatics — Posted on 2024-01-30

336 Embedding biomimetic vascular networks via coaxial sacrificial writing into functional tissue

Stankey, P. P.; Kroll, K. T.; Ainscough, A. J.; Reynolds, D. S.; Elamine, A.; Fichtenkort, B. T.; Uzel, S. G. M.; Lewis, J. A.

10.1101/2024.01.27.577581 — bioengineering — Posted on 2024-01-30

337 Single-use, Metabolite Absorbing, Resonant Transducer (SMART) culture vessels for label-free, continuous cell culture progression monitoring

Reuel, N. F.; Chan, Y. J.; Dileep, D.; Rothstein, S.; Cochran, E.

10.1101/2024.01.27.577601 — bioengineering — Posted on 2024-01-30

338 A unified model for cell-type resolution genomics from heterogeneous omics data

Chen, Z.; Rahmani, E.; Halperin, E.

10.1101/2024.01.27.577588 — genomics — Posted on 2024-01-30

339 Functional validation of EIF2AK4 (GCN2) missense variants associated with pulmonary arterial hypertension

Emanuelli, G.; Zhu, J.; Morrell, N.; Marciniak, S. J.

10.1101/2024.01.27.577559 — cell biology — Posted on 2024-01-30

340 Inhibition of miR-199b-5p reduces pathological alterations in Osteoarthritis by potentially targeting Fzd6 and Gcnt2.

Feng, T.; Zhang, Q.; Li, S.-H.; ping, y.-l.; tian, M.-q.; Zhou, S.-h.; Wang, X.; Wang, J.-M.; Liang, F.; Yu, S.-G.; Wu, Q.

10.1101/2023.10.03.560693 — molecular biology — Posted on 2024-01-30

341 Cisplatin drives mitochondrial dysregulation in sensory hair cells

Lee, D. S.; Schrader, A.; Zou, J.; Ang, W. H.; Warchol, M. E.; Sheets, L.

10.1101/2024.01.29.577846 — neuroscience — Posted on 2024-01-30

342 Impact of juglone on oral carcinogenesis induced by 4-nitroquinoline-1-oxide (4NQO) in rat model

Topal, O.; Topal, B.; Bas, Y.; Ongan, B.; Sadi, G.; Aslan, E.; Demirciler Yavas, B.; Pektas, M. B.

10.1101/2024.01.26.577505 — pharmacology and toxicology — Posted on 2024-01-30

343 A bird's eye view to the homeostatic, Alzheimer and Glioblastoma attractors

Nieves, J.; Gil, G.; Gonzalez, A.

10.1101/2023.11.23.568350 — biophysics — Posted on 2024-01-30

344 A learned score function improves the power of mass spectrometry database search

Ananth, V.; Sanders, J.; Yilmaz, M.; Oh, S.; Noble, W. S.

10.1101/2024.01.26.577425 — bioinformatics — Posted on 2024-01-30

345 TTSBBC: Triplex Target Site Biomarkers and Barcodes in Cancer

Ylagan, M.; Xu, Q.; Kowalski, J.

10.1101/2024.01.26.577471 — bioinformatics — Posted on 2024-01-30

346 From Planning Stage To FAIR Data: A Practical Metadatasheet For Biomedical Scientists

Seep, L.; Grein, S.; Splichalova, I.; Ran, D.; Mikhael, M.; Hildebrand, S.; Lauterbach, M.; Hiller, K.; Ribeiro, D. J. S.; Sieckmann, K.; Kardinal, R.; Huang, H.; Yu, J.; Kallabis, S.; Behrens, J.; Till, A.; Peeva, V.; Strohmeyer, A.; Bruder, J.; Blum, T.; Soriano-Arroquia, A.; Tischer, D.; Kuellmer, K.; Li, Y.; Beyer, M.; Gellner, A.-K.; Fromme, T.; Wackerhage, H.; Klingenspor, M.; Fenske, W. K.; Scheja, L.; Meissner, F.; Schlitzer, A.; Mass, E.; Wachten, D.; Latz, E.; Pfeifer, A.; Hasenauer, J.

10.1101/2024.01.27.577552 — bioinformatics — Posted on 2024-01-30

347 For antibody sequence generative modeling, mixture models may be all you need

Parkinson, J.; Wang, W.

10.1101/2024.01.27.577555 — bioinformatics — Posted on 2024-01-30

348 3D Bioprinting of Collagen-based Microfluidics for Engineering Fully-biologic Tissue Systems

Shiwarski, D. J.; Hudson, A. R.; Tashman, J. W.; Bakirci, E.; Moss, S. P.; Coffin, B. D.; Feinberg, A. W.

10.1101/2024.01.26.577422 — bioengineering — Posted on 2024-01-30

349 Suspension Electrospinning of Decellularized Extracellular Matrix

Jones, S.; VandenHeuval, S.; Luengo Martinez, A.; Burgeson, E.; Raghavan, S.; Rogers, S.; Cosgriff-Hernandez, E.

10.1101/2024.01.26.577473 — bioengineering — Posted on 2024-01-30

350 Polycaprolactone-based shape memory foams as self-fitting vaginal stents

Hicks, A. J.; Roberts, C.; Robinson, A.; Wilson, K.; Kotamreddy, V.; LaRue, T.; Veyssi, A.; Beltran, F.; Hakim, J.; Rausch, M. K.; Grunlan, M.; Cosgriff-Hernandez, E.

10.1101/2024.01.26.577474 — bioengineering — Posted on 2024-01-30

351 RAPID HEMATOCRIT ESTIMATION USING A FOLD-CREASE INDUCED FAST FLOWING PAPER SENSOR

Dash, A.; Mukhopadhyay, M.; Shaw, J.; Bhattacharyya, M.; DasGupta, S.

10.1101/2024.01.27.577541 — bioengineering — Posted on 2024-01-30

352 Using split protein reassembly strategy to optically control PLD enzymatic activity

yao, y.; Lou, X.; Li, J.; Zhu, M.; Qian, X.; Liu, J.; Zhang, L.; Zhang, P.; He, L.; Li, H.; Xu, Y.

10.1101/2024.01.27.577557 — cell biology — Posted on 2024-01-30

353 A trade-off between proliferation and defense in the fungal pathogen Cryptococcus at alkaline pH is controlled by the transcription factor GAT201

Hughes, E. S.; He, Z.; Tuck, L. R.; Ballou, E. R.; Wallace, E.

10.1101/2023.06.14.543486 — microbiology — Posted on 2024-01-30

354 A Multiscale Spatial Modeling Framework for the Germinal Center Response

Mu, D. P.; Scharer, C. D.; Kaminski, N. E.; Zhang, Q.

10.1101/2024.01.26.577491 — immunology — Posted on 2024-01-30

355 Functional characterization of the language network of polyglots and hyperpolyglots with precision fMRI

Malik-Moraleda, S.; Jouravlev, O.; Taliaferro, M.; Mineroff, Z.; Cucu, T.; Mahowald, K.; Blank, I. A.; Fedorenko, E.

10.1101/2023.01.19.524657 — neuroscience — Posted on 2024-01-30

356 Laboratory evaluation of the regeneration time, efficacy and wash-resistance of PermaNet(R) Dual (a deltamethrin-chlorfenapyr net) against susceptible and pyrethroid-resistant strains of Anopheles gambiae

Syme, T. W.; N'dombidje, B.; Todjinou, D.; Ariori, V.; Ngufor, C.

10.1101/2024.01.28.577674 — zoology — Posted on 2024-01-30

357 Characterization of RNA editing profiles in rice endosperm development

Chen, M.; Xia, L.; Tan, X.; Gao, S.; Wang, S.; Li, M.; Zhang, Y.; Xu, T.; Cheng, Y.; Chu, Y.; Hu, S.; Wu, S.; Zhang, Z.

10.1101/2024.01.27.577525 — bioinformatics — Posted on 2024-01-30

358 Initial pig developmental stage influences intestinal organoid growth but not phenotype

Duchesne, C.; Randuineau, G.; LE NORMAND, L.; Rome, V.; Laraqui, S.; Arnaud, A. P.; Boudry, G.

10.1101/2024.01.26.577507 — physiology — Posted on 2024-01-30

359 yQTL Pipeline: a structured computational workflow for large scale quantitative trait loci discovery and downstream visualization

Li, M.; Song, Z.; Gurinovich, A.; Schork, N.; Sebastiani, P.; Monti, S.

10.1101/2024.01.26.577518 — bioinformatics — Posted on 2024-01-30

360 MicroRNA-145 enhances lung cancer cell progression after exposure to lyophilized fertile hydatid cyst fluid of Echinococcus granulosus sensu stricto

Mosajakhah, H.; Shanehbandi, D.; Ahmadpour, E.; Mahami-Oskouei, M.; Janghoor, K. S.; Spotin, A.

10.1101/2024.01.26.577517 — immunology — Posted on 2024-01-30

361 Macrophage Polarizations in the Placenta and Lung are Associated with Bronchopulmonary Dysplasia

Mestan, K. K.; Sharma, A.; Lazar, S.; Pandey, S.; Parast, M. M.; Laurent, L. C.; Prince, L. S.; Sahoo, D.

10.1101/2024.01.26.577443 — systems biology — Posted on 2024-01-30

362 Efficient parameter estimation for ODE models of cellular processes using semi-quantitative data

Doresic, D.; Grein, S.; Hasenauer, J.

10.1101/2024.01.26.577371 — systems biology — Posted on 2024-01-30

363 Precision phenotyping of a barley diversity set reveals distinct drought response strategies

Paul, M.; Dalal, A.; Jääskeläinen, M.; Moshelion, M.; Schulman, A. H.

10.1101/2024.01.26.577377 — plant biology — Posted on 2024-01-30

364 Amphicarpic development in the emerging model organism Cardamine chenopodiifolia

Emonet, A.; Perez-Anton, M.; Neumann, U.; Dunemann, S.; Huettel, B.; Koller, R.; Hay, A.

10.1101/2024.01.26.577352 — plant biology — Posted on 2024-01-30

365 Electroanatomical Adaptations in the Guinea Pig Heart from Neonatal to Adulthood

Haq, K. T.; McLean, K.; Salameh, S.; Swift, L. M.; Posnack, N. G.

10.1101/2024.01.26.577234 — physiology — Posted on 2024-01-30

366 Non-physiologic interaction of MG53 with insulin receptor and lack of evidence for MG53's role in controlling insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues.

Lee, K. E.; Nishi, M.; Kim, J.; Murayama, T.; Dawson, Z.; Wang, X.; Zhou, X.; Tan, T.; Cai, C.; Takeshima, H.; Park, K. H.

10.1101/2024.01.26.576909 — physiology — Posted on 2024-01-30

367 Spaceflight increases sarcoplasmic reticulum Ca2+ leak and this cannot be counteracted with BuOE treatment

Braun, J. L.; Fajardo, V.

10.1101/2024.01.27.577549 — physiology — Posted on 2024-01-30

368 Transcriptomics effects of per- and polyfluorinated alkyl substances in differentiated neuronal cells

Running, L.; Karageorgiou, C.; Gokcumen, O.; Aga, D.; Atilla, G. E.

10.1101/2024.01.26.577438 — pharmacology and toxicology — Posted on 2024-01-30

369 Silver nanoparticles can be sampled by ultrafiltration probe but elution into & recovery from plasma and DPBS differs in vitro

risselada, m.; Mc Cain, R. R.; Bates, M. G.; Anderson, M.

10.1101/2024.01.26.577516 — pharmacology and toxicology — Posted on 2024-01-30

370 Nephrectomy and high-salt diet inducing pulmonary hypertension and kidney damage by increasing Ang II concentration in rats

Chen, Y.; Jiang, Q.; yang, q.; Zhang, C.; Hou, C.; hong, w.; du, m.; Shan, X.; li, x.; Zhou, D.; wen, d.; xiong, y.; Yang, K.; Lin, Z.; song, j.; mo, z.; Feng, H.; Xing, Y.; Fu, X.; Liu, C.; peng, f.; Li, B.; lu, w.; Yuan, J.; Wang, J.

10.1101/2024.01.25.577304 — pathology — Posted on 2024-01-30

371 A drug cocktail of rapamycin, acarbose, and phenylbutyrate enhances resilience to features of early-stage Alzheimer's disease in aging mice

Wezeman, J.; Darvas, M.; Postupna, N.; Klug, J.; Mangalindan, R. S.; Keely, A.; Nguyen, K.; Johnson, C.; Rosenfeld, M.; Ladiges, W.

10.1101/2024.01.26.577437 — pathology — Posted on 2024-01-30

372 Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2+ breast cancer

Baugh, A. G.; Gonzalez, E.; Narumi, V. H.; Kreger, J.; Liu, Y.; Rafie, C.; Castanon, S.; Jang, J.; Kagohara, L. T.; Anastasiadou, D. P.; Leatherman, J.; Armstrong, T. D.; Chan, I.; Karagiannis, G. S.; Jaffee, E. M.; MacLean, A.; Roussos Torres, E. T.

10.1101/2024.01.25.577282 — cancer biology — Posted on 2024-01-30

373 KR158 spheres harboring slow-cycling cells recapitulate GBM features in an immunocompetent system

Chakraborty, A.; Yang, C.; Kresak, J. L.; Silver, A.; Feier, D.; Tian, G.; Andrews, M.; Sobanjo, O. O.; Sobanjo, O. O.; Hodge, E. D.; Engelbart, M. K.; Huang, J.; Harrison, J. K.; Sarkisian, M.; Mitchell, D. A.; Deleyrolle, L. P.

10.1101/2024.01.26.577279 — cancer biology — Posted on 2024-01-30

374 A practical guide to time-resolved fluorescence microscopy and spectroscopy

Clark, B. S.; Silvernail, I.; Gordon, K.; Morgan, A. N.; Rolband, L. A.; Castaneda, J. F.; LeBlanc, S. J.

10.1101/2024.01.25.577300 — biophysics — Posted on 2024-01-30

375 The Flash Mode of Proton Irradiation in the Bragg Peak Partly Spares the Embryogenesis of the Quail

Akulinichev, S. V.; Glukhov, S. I.; Gavrilov, Y. K.; Kokontsev, D. A.; Kuznetsova, E. A.; Martynova, V. V.; Yakovlev, I. A.

10.1101/2024.01.27.577528 — biophysics — Posted on 2024-01-30

376 Reference-free Structural Variant Detection inMicrobiomes via Long-read Coassembly Graphs

Curry, K. D.; Yu, F. B.; Vance, S. E.; Segarra, S.; Bhaya, D.; Chikhi, R.; Rocha, E. P. C.; Treangen, T. J.

10.1101/2024.01.25.577285 — bioinformatics — Posted on 2024-01-30

377 NEAR: Neural Embeddings for Amino acid Relationships

Olson, D. R.; Demekas, D.; Colligan, T.; Wheeler, T.

10.1101/2024.01.25.577287 — bioinformatics — Posted on 2024-01-30

378 Adaptive, sample-specific parameter selection for more accurate transcript assembly

Shen, Y.; Yan, Z.; Kingsford, C.

10.1101/2024.01.25.577290 — bioinformatics — Posted on 2024-01-30

379 Rapid proteome-wide prediction of lipid-interacting proteins through ligand-guided structural genomics

Chou, J. C.-C.; Decosto, C. M.; Chatterjee, P.; Dassama, L. M. K.

10.1101/2024.01.26.577452 — bioinformatics — Posted on 2024-01-30

380 Frequently Together, Among Model Systems Molecular Alterations: Cancer Maintenance Markers with Translational Study Design

Ylagan, M.; Xu, Q.; Kowalski, J.

10.1101/2024.01.26.577415 — bioinformatics — Posted on 2024-01-30

381 Using large scale transfer learning to highlight the role of chromatin state in intron retention

Daoud, A.; Ben-Hur, A.

10.1101/2024.01.26.577402 — bioinformatics — Posted on 2024-01-30

382 QUAL-IF-AI: Quality Control of Immunofluorescence Images using Artificial Intelligence

Andhari, M. D.; Rinaldi, G.; Nazari, P.; Shankar, G.; Dubroja Lakic, N.; Vets, J.; Ostyn, T.; Vanmechelen, M.; Decraene, B.; Arnould, A.; Mestdagh, W.; De Moor, B.; De Smet, F.; Bosisio, F. M.; Antoranz, A.

10.1101/2024.01.26.577391 — bioinformatics — Posted on 2024-01-30

383 Epigenomics coverage data extraction and aggregation in R with tidyCoverage

SERIZAY, J.; Koszul, R.

10.1101/2024.01.27.577537 — bioinformatics — Posted on 2024-01-30

384 Integration of hyperspectral imaging and transcriptomics from individual cells with HyperSeq

Xie, Y.; Habibalahi, A.; Anwer, A. G.; Wahi, K.; Gatt, C.; Johansson, E. M. V.; Holst, J.; Goldys, E.; Zanini, F.

10.1101/2024.01.27.577536 — bioinformatics — Posted on 2024-01-30

385 A Bioengineered Platform for Enhanced Observability of Patterned Gastrointestinal Organoid Monolayers with Bilateral Access

Hofer, M.; Duque-Correa, M. A.; Lutolf, M. P.

10.1101/2024.01.26.577381 — bioengineering — Posted on 2024-01-30

386 Identifying genomic data use with the Data Citation Explorer

Byers, N.; Parker, C.; Beecroft, C.; Reddy, T. B. K.; Salamon, H.; Garrity, G.; Fagnan, K.

10.1101/2024.01.26.577091 — genomics — Posted on 2024-01-30

387 Highly Contiguous Genome Assembly of Drosophila prolongata - a Model for Evolution of Sexual Dimorphism and Male-specific Innovations

Luecke, D.; Luo, Y.; Krzystek, H.; Jones, C.; Kopp, A.

10.1101/2024.01.29.577853 — genomics — Posted on 2024-01-30

388 Detecting superspreaders in wildlife reservoirs of disease

Konzen, E.; Delahay, R. J.; Hodgson, D. J.; McDonald, R. A.; Brooks Pollock, E.; Spencer, S. E. F.; McKinley, T. J.

10.1101/2024.01.26.576600 — ecology — Posted on 2024-01-30

389 Plankton dynamics of Milicz Ponds: indicators ofsustainability and anthropogenic driven threats

Mukherjee, M.; Jarzembowski, P.; Polechonski, R.; Prockow, J.

10.1101/2024.01.26.577523 — ecology — Posted on 2024-01-30

390 Interferon-γ signaling in eosinophilic esophagitis has implications for epithelial barrier function and programmed cell death.

Lal, M.; Burk, C. M.; Gautam, R.; Mrozek, Z.; Trachsel, T.; Beers, J. T.; Carroll, M. C.; Morgan, D. M.; Muir, A. B.; Shreffler, W. G.; Ruffner, M. A.

10.1101/2024.01.26.577407 — immunology — Posted on 2024-01-30

391 DCs targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors

Lopez, L.; Morosi, L. G.; La Terza, F.; Bourdely, P.; Rospo, G.; Amadio, R.; Piperno, G. M.; Russo, V.; Volponi, C.; Vodret, S.; Joshi, S.; Giannese, F.; Lazarevic, D.; Germano, G.; Stoitzner, P.; Bardelli, A.; DALOD, M.; Pace, L.; Caronni, N.; Guermonprez, P.; Benvenuti, F.

10.1101/2024.01.26.576259 — immunology — Posted on 2024-01-30

392 PVRL2 Suppresses Anti-tumor Immunity Through PVRIG- and TIGIT-Independent Pathways

Yang, J.; Wang, L.; Byrnes, J. R.; Kirkemo, L. L.; Driks, H.; Belair, C.; Aguilar, O. A.; Lanier, L. L.; Wells, J. A.; Fong, L.; Blelloch, R.

10.1101/2024.01.26.577132 — immunology — Posted on 2024-01-30

393 Impact of IL-21 on Natural Killer cell proliferation and Function - a mathematical and functional assessment

Biondo, R.; Nayak, I.; Möker, N.; Zhang, C.; Stewart, W. C.; Khakoo, S. I.; Das, J.

10.1101/2024.01.26.577405 — immunology — Posted on 2024-01-30

394 Cholinergic agonist PNU282987 induces pro-inflammatory gene expression via the MCOLN1-TFEB pathway in murine macrophages.

Honwad, H. H.; Najibi, M.; Koscso, B.; Bogunovic, M.; Irazoqui, J. E.

10.1101/2024.01.26.577408 — immunology — Posted on 2024-01-30

395 Adult sex change leads to extensive forebrain reorganization in clownfish

Parker, C. G.; Gruenhagen, G. W.; Hegarty, B. E.; Histed, A. R.; Streelman, J. T.; Rhodes, J. S.; Johnson, Z. V.

10.1101/2024.01.29.577753 — neuroscience — Posted on 2024-01-30

396 Spike transmission failures in axons from mouse cortical pyramidal neurons in vivo

Ofer, N.; Cornejo, V. H.; Yuste, R.

10.1101/2024.01.29.577733 — neuroscience — Posted on 2024-01-30

397 Non-CG DNA methylation and MeCP2 stabilize repeated tuning of long genes that distinguish closely related neuron types

Moore, J. R.; Nemera, M. T.; D'Souza, R. D.; Hamagami, N.; Clemens, A. W.; Beard, D. C.; Urman, A.; Mendoza, V. R.; Gabel, H. W.

10.1101/2024.01.30.577861 — neuroscience — Posted on 2024-01-30

398 Proximity labeling proteomics reveals Kv1.3 potassium channel immune interactors in microglia.

Bowen, C. A.; Nguyen, H. M.; Lin, Y.; Bagchi, P.; Natu, A.; Espinosa-Garcia, C.; Werner, E.; Kumar, P.; Tobin, B.; Wood, L. B.; Faundez, V.; Wulff, H.; Seyfried, N.; Rangaraju, S.

10.1101/2024.01.29.577122 — neuroscience — Posted on 2024-01-30

399 Modulation of locomotion and motor neuron response by the cohesive effect of acute and chronic feeding states and acute d-amphetamine treatment in zebrafish larvae.

Roitman, M. F.; Jung, E. E.; Bansal, P.

10.1101/2024.01.28.577634 — neuroscience — Posted on 2024-01-30

400 The CD74 inhibitor DRhQ improves cognition and mitochondrial function in 5xFAD mouse model of Aβ accumulation

Gladen-Kolarsky, N.; Neff, C. J.; Hack, W.; Brandes, M. S.; Wiedrick, J.; Meza-Romero, R.; Lockwood, D. R.; Quinn, J. F.; Offner, H.; Vandenbark, A. A.; Gray, N. E.

10.1101/2024.01.29.577832 — neuroscience — Posted on 2024-01-30

401 Hydrodynamic function of genal prolongations in trinucleimorph trilobites revealed by computational fluid dynamics

Pates, S.; Drage, H. B.

10.1101/2024.01.26.577348 — paleontology — Posted on 2024-01-30

402 Comprehensive benchmark of integrative strategies for analyzing microbiome-metabolome relationships

Mangnier, L.; Mariaz, M.; Vashist, N.; Mathieu, A.; Bodein, A.; Scott-Boyer, M.-P.; Bramble, M.; Droit, A.

10.1101/2024.01.26.577441 — bioinformatics — Posted on 2024-01-30

403 Proteostatic remodeling of small heat shock chaperones - crystallins by Ran-binding protein 2 and the peptidyl-prolyl cis-trans isomerase and chaperone activities of its cyclophilin domain.

Patil, H.; Cho, K.-i.; Ferreira, P. A.

10.1101/2024.01.26.577462 — genetics — Posted on 2024-01-30

404 Creating something out of nothing: Symbolic and non-symbolic representations of numerical zero in the human brain

Barnett, B.; Fleming, S. M.

10.1101/2024.01.30.577906 — neuroscience — Posted on 2024-01-30

405 Cellular Modeling of CLN6 with IPSC-derived Neurons and Glia

Otero, M. G.; Kim, J.; Kumar, Y.; Rajewski, A.; Nonis, F. D.; Santiskulvong, C.; Bannykh, S.; Oza, H.; Farooqi, H. M. U.; Babros, M.; Freeman, C.; Dupuis, L.; Andrews, S.; Mendoza, R.; Bresee, C.; Adams, D.; Tifft, C.; Toro, C.; Khanlou, N.; Gahl, W. A.; Salamon, N.; Pierson, T. M.

10.1101/2024.01.29.577876 — neuroscience — Posted on 2024-01-30

406 Multiplexed Short-wave Infrared Imaging Highlights Anatomical Structures in Mice

Zhong, X.; Patel, A.; Sun, Y.; Saeboe, A. M.; Dennis, A. M.

10.1101/2024.01.29.577849 — bioengineering — Posted on 2024-01-30

407 Towards the identification of the molecular toolkit involved in scale worm bioluminescence (Polinoidae, Annelida)

Gracia-Sancha, C.; Conejero, M.; Taboada, S.; Martin, D.; Riesgo, A.; Holford, M.; Verdes, A.

10.1101/2024.01.28.577566 — evolutionary biology — Posted on 2024-01-30

408 Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress

Leeson, H. C.; Aguado, J.; Gomez-Inclan, C.; Chaggar, H. K.; Taherian Fard, A.; Hunter, Z.; Lavin, M. F.; Mackay-Sim, A.; Wolvetang, E. J.

10.1101/2024.01.29.577683 — cell biology — Posted on 2024-01-30

409 Synaptic and dendritic architecture of different types of hippocampal somatostatin interneurons

Takacs, V.; Bardoczi, Z.; Orosz, A.; Major, A.; Tar, L.; Berki, P.; Papp, P.; Mayer, M. I.; Sebok, H.; Zsolt, L.; Sos, K. E.; Kali, S.; Freund, T. F.; Nyiri, G.

10.1101/2023.05.14.540675 — neuroscience — Posted on 2024-01-30

410 Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders.

Carbonell-Roig, J.; Aaltonen, A.; Cartocci, V.; McGuirt, A.; Mosharov, E.; Kehr, J.; Lieberman, O. J.; Sulzer, D.; Borgkvist, A.; Santini, E.

10.1101/2024.01.29.577831 — neuroscience — Posted on 2024-01-30

411 Specific amygdala and hippocampal subfield volumes in social anxiety disorder and their relation to clinical characteristics; an international mega-analysis

Ntwatwa, Z.; Sprecklemeyer, J.; Bas-Hoogendam, J. M.; van Honk, J.; Mufford, M.; Boraxbekk, C.-J.; Cremers, H. R.; Fouche, J.-P.; Frick, A.; Furmark, T.; Klumpp, H.; Lochner, C.; Luan Phan, K.; Mansson, K. N. T.; Pannekoek, N.; Peterburs, J.; Roelofs, K.; Roos, A.; Straube, T.; van Steenbergen, H.; Van Tol, M.-J.; Veltman, D. J.; van der Wee, N. J. A.; Stein, D. J.; Ipser, J.; Groenewold, N.

10.1101/2024.01.29.576056 — neuroscience — Posted on 2024-01-30

412 Scale-Dependent Coding of the Hippocampus in Relational Memory

ding, w.; Lin, Y.; Zhang, B.; Liu, J.

10.1101/2024.01.29.577883 — neuroscience — Posted on 2024-01-30

413 LHX2 regulates dendritic morphogenesis in layer II/III of the neocortex via distinct pathways in progenitors and postmitotic neurons.

Bose, M.; Ravindran, S.; Kumari, S.; Iyer, A.; Vedak, B.; Srivastava, A.; Talwar, I.; Narayanan, R.; Tole, S.

10.1101/2024.01.30.577728 — neuroscience — Posted on 2024-01-30

414 Just-in-time: gaze guidance in natural behavior

Keshava, A.; Nezami, F. N.; Neumann, H.; Izdebski, K.; Schueler, T.; Koenig, P.

10.1101/2021.01.29.428782 — neuroscience — Posted on 2024-01-30

415 Adaptive and pleiotropic effects of evolution in synonymous sugar environments.

Ahlawat, N.; Venkataraman, P.; Mahilkar, A.; Brajesh, R. G.; Saini, S.

10.1101/2024.01.28.577607 — evolutionary biology — Posted on 2024-01-30

416 Protein sequence landscapes are not so simple: on reference-free versus reference-based inference

Dupic, T.; Phillips, A. M.; Desai, M. M.

10.1101/2024.01.29.577800 — evolutionary biology — Posted on 2024-01-30

417 Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro

Harris, S. E.; Alexis, M. S.; Giri, G.; Cavazos, F. F.; Murn, J.; Aleman, M. M.; Burge, C. B.; Dominguez, D.

10.1101/2024.01.29.577729 — evolutionary biology — Posted on 2024-01-30

418 Population genetics, phylogeography and gene flow of mainland and island vampire bat (Desmodus rotundus) populations: an investigation into mainland-island bat movement

Seetahal, J. F. R.; Streicker, D. G.; Beerli, P.; Sahadeo, N.; Lemey, P.; Sanchez-Vazquez, M. J.; Broos, A.; Bergner, L.; Ramkissoon, V.; Mahabir, R.; Tihul, P.; Hartley, D.; Van Sauers, A.; Karg, G.; Mohammed, R. S.; Biek, R.; Oura, C. A. L.; Carrington, C. V. F.

10.1101/2024.01.29.577751 — evolutionary biology — Posted on 2024-01-30

419 Complex Hybridization in a Clade of Polytypic Salamanders (Plethodontidae: Desmognathus) Uncovered by Estimating Higher-Level Phylogenetic Networks

Pyron, R. A.; O'Connell, K.; Myers, E.; Beamer, D.; Banos, H.

10.1101/2024.01.29.577868 — evolutionary biology — Posted on 2024-01-30

420 Spectral variation and pigmentary basis of ornamental and mimetic wing colour patches of swallowtail butterflies

Dharmaraaj, B.; Venkatesan, R.; Kunte, K.

10.1101/2024.01.28.577613 — evolutionary biology — Posted on 2024-01-30

421 Translation of zinc finger domains induces ribosome collision and Znf598-dependent mRNA decay in vertebrates

Ishibashi, K.; Shichino, Y.; Han, P.; Wakabayashi, K.; Inada, T.; Kimura, S.; Iwasaki, S.; Mishima, Y.

10.1101/2023.07.10.548350 — molecular biology — Posted on 2024-01-30

422 Genomic diversity of novel strains of mammalian gut microbiome derived Clostridium XIVa strains is driven by mobile genetic element acquisition

Kamat, M.; Ormsby, M. J.; Humphrey, S.; Dixit, S. K.; Thummler, K.; Lapsley, C.; Crouch, K.; Jukes, C.; Hulme, H.; Burchmore, R.; Meikle, L.; Pritchard, L.; Wall, D. M.

10.1101/2024.01.22.576618 — microbiology — Posted on 2024-01-30

423 A galanin-positive population of lumbar spinal cord neurons modulates sexual excitation and copulatory behavior

Lenschow, C.; Mendes, A. P.; Ferreira, L.; Lacoste, B.; Quilgars, C.; Bertrand, S. S.; Lima, S. Q.

10.1101/2022.10.04.510783 — neuroscience — Posted on 2024-01-30

424 Precision of the Integrated Cognitive Assessment for the assessment of neurocognitive performance in athletes

Glassbrook, D. J.; Chazot, P. L.; Hind, K.

10.1101/2023.03.22.533746 — neuroscience — Posted on 2024-01-30

425 Combining RASG12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold tumours hot

Anastasiou, P.; Moore, C.; Rana, S.; de Castro, A.; Tomaschko, M.; Boumelha, J.; Mugarza, E.; Blaj, C.; de Carne Trecesson, S.; Goldstone, R.; Smith, J.; Quintana, E.; Molina-Arcas, M.; Downward, J.

10.1101/2024.01.15.575765 — cancer biology — Posted on 2024-01-30

426 Individual Behavioral Variability Across Time and Contexts in Dendrobates tinctorius Poison Frogs

Soto, K. M.; Hardin, F. O.; Alleyne, H. P.; Fischer, E. K.

10.1101/2023.09.25.559405 — animal behavior and cognition — Posted on 2024-01-30

427 A single-cell strategy for the identification of intronic variants related to mis-splicing in pancreatic cancer

Duman, E. T.; Sitte, M.; Conrads, K.; Mackay, A.; Ludewig, F.; Stroebel, P.; Ellenrieder, V.; Hessmann, E.; Papantonis, A.; Salinas, G.

10.1101/2023.05.08.539836 — genomics — Posted on 2024-01-30

428 Proteome-scale prediction of molecular mechanisms underlying dominant genetic diseases

Badonyi, M.; Marsh, J. A.

10.1101/2023.09.08.556798 — genetics — Posted on 2024-01-30

429 How do plant RNA viruses overcome the negative effect of Muller s ratchet despite strong transmission bottlenecks?

LAFFORGUE, G.; LEFEBVRE, M.; MICHON, T.; Elena, S. F.

10.1101/2023.08.01.550272 — evolutionary biology — Posted on 2024-01-30

430 Spring reproductive success influences autumnal malarial load in a passerine bird

Pigeault, R.; Cozzarolo, C.-S.; Wassef, J.; Gremion, J.; Bastardot, M.; Glaizot, O.; Christe, P.

10.1101/2023.07.28.550923 — ecology — Posted on 2024-01-30

431 The nuclear basket regulates the distribution and mobility of nuclear pore complexes in budding yeast

Zsok, J.; Simon, F.; Bayrak, G.; Isaki, L.; Kerff, N.; Wolstenholme, A.; Weiss, L. E.; Dultz, E.

10.1101/2023.09.28.558499 — cell biology — Posted on 2024-01-30

432 A Remarkable Genetic Shift in a Transmitted/Founder Virus Broadens Antibody Responses Against HIV-1

Jain, S.; Uritskiy, G.; Mahalingam, M.; Batra, H.; Chand, S.; Trinh, H.; Beck, C.; Shin, W.-H.; AlSalmi, W.; Kijak, G.; Eller, L. A.; Kim, J.; Kihara, D.; Tovanabutra, S.; Ferrari, G.; Robb, M.; Rao, M.; Rao, V. B.

10.1101/2021.06.16.448593 — microbiology — Posted on 2024-01-30

433 Rapid, systematic updating of movement by accumulated decision evidence

Molano-Mazon, M.; Garcia-Duran, A.; Pastor-Ciurana, J.; Hernandez-Navarro, L.; Bektic, L.; Lombardo, D.; de la Rocha, J.; Hyafil, A.

10.1101/2023.11.09.566389 — neuroscience — Posted on 2024-01-30

434 Comparative Analysis of Biomarkers in Type 2 Diabetes Patients with and without Comorbidities: Insights into the Role of Hypertension and Cardiovascular Disease

SAVVOPOULOS, S. V.; Hatzikirou, H.; Jelinek, H.

10.1101/2024.01.25.577186 — bioinformatics — Posted on 2024-01-30

435 AraMultiOmics: a tool for generating multi-omics features for downstream statistical analysis to infer the molecular basis of symbiosis among non-host plant Arabidopsis thaliana, host plant, and arbuscular mycorrhizal fungi

Kang, J. E.

10.1101/2023.11.01.565228 — bioinformatics — Posted on 2024-01-30

436 Investigation of Biomedical Cell Image Cryptography Based on RC4 Technique

Jiang, S.; Kumar, E.

10.1101/2023.12.29.573618 — bioengineering — Posted on 2024-01-30

437 Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

Borar, P.; Biswas, T.; Chaudhuri, A.; Huxford, T.; Chakrabarti, S.; Ghosh, G.; Polley, S.

10.1101/2023.06.27.546692 — biochemistry — Posted on 2024-01-30

438 General solution to inflated type I and II errors in multi-subject single-cell differential gene expression analysis

Lee, H.; Han, B.

10.1101/2023.01.09.523212 — genomics — Posted on 2024-01-30

439 Cost-Effective Approaches to Elucidate Intergeneric Relationships of Plants: Utilizing Multiple Conserved Nuclear Genes and Whole Chloroplast Genomes

Witharana, E. P.; San, M. H.; Jayawardana, N. U.; Kotoda, N.; Yamamoto, M.; Nagano, Y.

10.1101/2024.01.15.575800 — genomics — Posted on 2024-01-30

440 A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. et sp. nov. (Ochrophyta) push the frontiers of organellar biology

Barcyte, D.; Jaske, K.; Panek, T.; Yurchenko, T.; Sevcikova, T.; Eliasova, A.; Elias, M.

10.1101/2022.04.05.487141 — evolutionary biology — Posted on 2024-01-30

441 The distribution of fitness effects during adaptive walks using a simple genetic network

O'Brien, N. L. V.; Holland, B.; Engelstaedter, J.; Ortiz-Barrientos, D.

10.1101/2023.10.26.564303 — evolutionary biology — Posted on 2024-01-30

442 Improved mRNA electroporation into immature oocytes to examine protein dynamics during development

Satouh, Y.; Suzuki, E.; Sasaki, K.; Sato, K.

10.1101/2023.12.07.570343 — developmental biology — Posted on 2024-01-30

443 Cell Adhesion-Dependent Biphasic Axon Outgrowth Elucidated by Femtosecond Laser Impulse

Yamada, S.; Baba, K.; Inagaki, N.; Yoichiroh, H.

10.1101/2021.10.10.463848 — cell biology — Posted on 2024-01-30

444 Structure-Guided Mutagenesis Targeting Interactions between pp150 Tegument Protein and Small Capsid Protein Identifies Five Lethal and Two Live Attenuated HCMV Mutants

Stevens, A. W.; Cruz-Cosme, R.; Armstrong, N.; Tang, Q.; Zhou, Z. H.

10.1101/2024.01.22.576707 — microbiology — Posted on 2024-01-30

445 Alpha phase-coding supports feature binding during working memory maintenance

Pagnotta, M. F.; Santo-Angles, A.; Temudo, A.; Barbosa, J.; Compte, A.; D'Esposito, M.; Sreenivasan, K. K.

10.1101/2024.01.21.576561 — neuroscience — Posted on 2024-01-30

446 Epileptic responses in marmosets induced by knockdown of CREB Regulated Transcription Coactivator 1 (CRTC1)

Nakagami, Y.; Komatsu, M.; Nakae, K.; Ohtsuka, M.; Hata, J.; Mizukami, H.; Takemori, H.; Ishii, S.; Okano, H.; Watakabe, A.; Yamamori, T.

10.1101/2023.09.22.558929 — neuroscience — Posted on 2024-01-30

447 Expression-based machine learning models for predicting plant tissue identity

Palande, S.; Arsenault, J.; Basurto-Lozada, P.; Bleich, A.; Brown, B. N. I.; Buysse, S. F.; Connors, N. A.; Das Adhikari, S.; Dobson, K. C.; Guerra-Castillo, F. X.; Guerrero-Carrillo, M. F.; Harlow, S.; Herrera-Orozco, H.; Hightower, A. T.; Izquierdo, P.; Jacobs, M.; Johnson, N. A.; Leuenberger, W.; Lopez-Hernandez, A.; Luckie-Duque, A.; Martinez-Avila, C.; Mendoza-Galindo, E.; Plancarte, D.; Schuster, J. M.; Shomer, H.; Sitar, S. C.; Steensma, A. K.; Thomson, J. E.; Villasenor-Amador, D.; Waterman, R.; Webster, B. M.; Whyte, M.; Zorrilla-Azcue, S.; Montgomery, B. L.; Husbands, A. Y.; Krishnan

10.1101/2023.08.20.554029 — plant biology — Posted on 2024-01-30

448 Cell polarity proteins promote macropinocytosis in response to metabolic stress

Lambies, G.; Lee, S.-W.; Duong-Polk, K.; Aza-Blanc, P.; Maganti, S.; Dawson, D. W.; Commisso, C.

10.1101/2024.01.16.575943 — cancer biology — Posted on 2024-01-30

449 Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics

Ose, N. J.; Campitelli, P. J.; Modi, T.; Kazan, I. C.; Kumar, S.; Ozkan, S. B.

10.1101/2023.09.14.557827 — biophysics — Posted on 2024-01-30

450 Chromatin phase separation and nuclear shape fluctuations are correlated in a polymer model of the nucleus

Attar, A. G.; Paturej, J.; Banigan, E.; Erbas, A.

10.1101/2023.12.16.571697 — biophysics — Posted on 2024-01-30

451 Functional Protein Dynamics in a Crystal

Klyshko, E.; Kim, J. S.-H.; McGough, L.; Valeeva, V.; Lee, E.; Ranganathan, R.; Rauscher, S.

10.1101/2023.07.06.548023 — biophysics — Posted on 2024-01-30

452 MELISSA: Semi-Supervised Embedding for Protein Function Prediction Across Multiple Networks

Wu, K.; Zhou, D.; Slonim, D.; Hu, X.; Cowen, L.

10.1101/2023.08.09.552672 — bioinformatics — Posted on 2024-01-30

453 Improving generalizability for MHC-I binding peptide predictions through structure-based geometric deep learning

Marzella, D. F.; Crocioni, G.; Radusinovic, T.; Lepikhov, D.; Severin, H.; Bodor, D. L.; Rademaker, D. T.; Lin, C.; Georgievska, S.; Renaud, N.; Kessler, A. L.; Lopez-Tarifa, P.; Buschow, S.; Bekkers, E.; Xue, L. C.

10.1101/2023.12.04.569776 — bioinformatics — Posted on 2024-01-30

454 A Biophysical Model for ATAC-seq Data Analysis

Felce, C.; Gorin, G.; Pachter, L.

10.1101/2024.01.25.577262 — bioinformatics — Posted on 2024-01-30

455 Remotely controlled drug release in deep brain regionsof non-human primates

Wilson, M. G.; Webb, T. D.; Odeen, H.; Kubanek, J.

10.1101/2023.10.09.561539 — bioengineering — Posted on 2024-01-30

456 Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

Sperry, M. M.; Charrez, B.; Fotowat, H.; Gardner, E.; Pilobello, K.; Izadifar, Z.; Lin, T.; Kuelker, A.; Kaki, S.; Lewandowski, M.; Lightbown, S.; Martinez, R.; Marquez, S.; Moore, J.; Plaza-Oliver, M.; Sesay, A.; Shcherbina, K.; Sheehan, K.; Takeda, T.; Del Campo, D.; Andrijauskaite, K.; Cisneros, E.; Lopez, R.; Cano, I.; Maxwell, Z.; Jessop, I.; Veraza, R.; Bunegin, L.; Percival, T. J.; Weitzel, E.; Sleeter, J. J.; Parry, O. G.; Yracheta, J.; Pena, J. J.; Wood, D. M.; Homas, Z. T.; Hinshaw, C. J.; Cox-Hinshaw, J.; Levin, M.; Super, M.; Novak, R.; Ingber, D. E.

10.1101/2023.02.27.530270 — bioengineering — Posted on 2024-01-30

457 A multi-hierarchical approach reveals D-serine as a hidden substrate of sodium-coupled monocarboxylate transporters

Wiriyasermkul, P.; Moriyama, S.; Suzuki, M.; Kongpracha, P.; Nakamae, N.; Takeshita, S.; Tanaka, Y.; Matsuda, A.; Miyasaka, M.; Hamase, K.; Kimura, T.; Mita, M.; Sasabe, J.; Nagamori, S.

10.1101/2020.08.10.244822 — biochemistry — Posted on 2024-01-30

458 Investigation of Two-Component Hydrogel System for the Tissue Regeneration from Simulation

Jiang, S.; Kumar, E.

10.1101/2023.12.28.573564 — biochemistry — Posted on 2024-01-30

459 Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens

Jiang, L.; Dalgarno, C.; Papalexi, E.; Mascio, I.; Wessels, H.-H.; Yun, H.; Iremadze, N.; Lithwick-Yanai, G.; Lipson, D.; Satija, R.

10.1101/2024.01.29.576933 — genomics — Posted on 2024-01-30

460 The first chromosome-level annotated reference genome for Chrosomus eos, the northern redbelly dace

Schultz, B.; Mandeville, E. G.

10.1101/2023.12.21.572839 — genomics — Posted on 2024-01-30

461 Population genomics of harbour seal Phoca vitulina from northern British Columbia through California and comparison to the Atlantic subspecies

Sutherland, B. J. G.; Rycroft, C.; Duguid, A.; Beacham, T. D.; Tucker, S.

10.1101/2023.05.12.540438 — genomics — Posted on 2024-01-30

462 Chromosome-level assembly of the gray fox (Urocyon cinereoargenteus) confirms the basal loss of PRDM9 in Canidae

Armstrong, E. E.; Bissell, K. L.; Heikkinen, M. A.; Jessup, A.; Junaid, M. O.; Lee, D. H.; Lieb, E. C.; Liem, J. T.; Martin, E. M.; Moreno, M.; Otgonbayar, K.; Romans, B. W.; Royar, K.; Adler, M. B.; Needle, D. B.; Harkess, A.; Kelley, J. L.; Mooney, J. A.; Mychajliw, A. M.

10.1101/2023.11.08.566296 — genomics — Posted on 2024-01-30

463 Highly parameterized polygenic scores tend to overfit to population stratification via random effects

Aw, A. J.; McRae, J.; Rahmani, E.; Song, Y. S.

10.1101/2024.01.27.577589 — genetics — Posted on 2024-01-29

464 Assessing the potential of germplasm collections for the management of genetic diversity: the case of the French National Cryobank

Jacques, A.; Duclos, D.; Danchin-Burge, C.; Mercat, M.-J.; Tixier-Boichard, M.; Restoux, G.

10.1101/2023.07.19.549644 — genetics — Posted on 2024-01-30

465 C. elegans epicuticlins define specific compartments in the apical extracellular matrix and function in wound repair

Pooranachithra, M.; Jyo, E. M.; Ernst, A. M.; Chisholm, A. D.

10.1101/2024.01.12.575393 — developmental biology — Posted on 2024-01-30

466 Tubulin polyglutamylation patterns are central to axon guidance via selective regulation of microtubule-severing enzymes

Ten Martin, D.; Jardin, N.; Vougny, J.; Giudicelli, F.; Gasmi, L.; Henriot, V.; Lebrun, L.; Haumaitre, C.; Kneussel, M.; Nicol, X.; Janke, C.; Magiera, M. M.; Hazan, J.; Fassier, C.

10.1101/2022.01.20.477127 — developmental biology — Posted on 2024-01-30

467 Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice

Li, A.; Yi, J.; Li, X.; Dong, L.; Ostrow, L. W.; Ma, J.; Zhou, J.

10.1101/2023.02.12.528218 — cell biology — Posted on 2024-01-30

468 Variability in HIV-1 Transmitted/Founder Virus Susceptibility to Combined APOBEC3F and APOBEC3G Host Restriction

Gaba, A.; Yousefi, M.; Bhattacharjee, S.; Chelico, L.

10.1101/2024.01.25.577241 — microbiology — Posted on 2024-01-30

469 An enduring role for hippocampal pattern completion in addition to an emergent non-hippocampal contribution to holistic episodic retrieval after a 24-hour delay

Joensen, B.; Ashton, J.; Berens, S. C.; Gaskell, G.; Horner, A. J.

10.1101/2023.09.15.557911 — neuroscience — Posted on 2024-01-30

470 Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories

R.G., R.; Ascoli, G. A.; Sutton, N. M.; Dannenberg, H.

10.1101/2023.05.30.542747 — neuroscience — Posted on 2024-01-30

471 The Layer 7 Cortical Interface: A Scalable and Minimally Invasive Brain-Computer Interface Platform

Hettick, M.; Ho, E.; Poole, A. J.; Monge, M.; Papageorgiou, D.; Takahashi, K.; LaMarca, M.; Trietsch, D.; Reed, K.; Murphy, M.; Rider, S.; Gelman, K. R.; Byun, Y. W.; Hanson, T.; Tolosa, V.; Lee, S.-H.; Bhatia, S.; Konrad, P. E.; Mager, M.; Mermel, C. H.; Rapoport, B. I.

10.1101/2022.01.02.474656 — neuroscience — Posted on 2024-01-30

472 Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

Gazula, H.; Tregidgo, H.; Billot, B.; Balbastre, Y.; Williams-Ramirez, J.; Herisse, R.; Deden-Binder, L. J.; Casamitjana, A.; Melief, E. J.; Latimer, C. S.; Kilgore, M. D.; Montine, M.; Robinson, E.; Blackburn, E.; Marshall, M. S.; Connors, T. R.; Oakley, D. H.; Frosh, M. P.; Young, S. I.; Van Leemput, K.; Dalca, A. V.; Fischl, B.; Mac Donald, C. L.; Keene, C. D.; Hyman, B.; Iglesias, J. E.

10.1101/2023.06.08.544050 — neuroscience — Posted on 2024-01-30

473 Brain2GAN: Feature-disentangled neural encoding and decoding of visual perception in the primate brain

Dado, T.; Papale, P.; Lozano, A.; Le, L.; Wang, F.; van Gerven, M.; Roelfsema, P.; Güclütürk, Y.; Güclü, U.

10.1101/2023.04.26.537962 — neuroscience — Posted on 2024-01-30

474 Early dynamics of excitation and inhibition maintain late frequency tuning in auditory cortex

Reid, A. P.; Zador, A. M.; Hromadka, T.

10.1101/2024.01.26.577483 — neuroscience — Posted on 2024-01-30

475 Rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning

Olszynski, K. H.; Polowy, R.; Wardak, A. D.; Laska, I. A.; Grymanowska, A. W.; Pulawski, W.; Gawrys, O.; Kolinski, M.; Filipkowski, R. K.

10.1101/2023.04.06.535936 — neuroscience — Posted on 2024-01-30

476 Predicting bonds between collagens: An alignment approach

Wesp, V.; Scholz, L.; Ziermann-Canabarro, J. M.; Schuster, S.; Stark, H.

10.1101/2023.08.25.554753 — systems biology — Posted on 2024-01-30

477 Investigating RNA splicing as a source of cellular diversity using a binomial mixture model

Isaev, K.; Knowles, D. A.

10.1101/2023.10.17.562774 — systems biology — Posted on 2024-01-30

478 Threshold-awareness in adaptive cancer therapy

Wang, M.; Scott, J. G.; Vladimirsky, A.

10.1101/2022.06.17.496649 — cancer biology — Posted on 2024-01-30

479 Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory

Feierman, E. R.; Louzon, S.; Prescott, N. A.; Biaco, T.; Gao, Q.; Qiu, Q.; Choi, K.; Palozola, K. C.; Voss, A. J.; Mehta, S.; Quaye, C.; Lynch, K.; Fuccillo, M. V.; Wu, H.; David, Y.; Korb, E.

10.1101/2024.01.29.575103 — genetics — Posted on 2024-01-30

480 The investigation of dysregulated visual perceptual organization in adults with autism spectrum disorders with phase-amplitude coupling and directed connectivity

Sun, L.

10.1101/2024.01.25.577004 — neuroscience — Posted on 2024-01-29

481 Mathematical model of replication-mutation dynamics in coronaviruses

Blyuss, K. B.; Kyrychko, Y. N.

10.1101/2024.01.29.577716 — systems biology — Posted on 2024-01-29

482 graded-CRISPRi, a novel tool for tuning the strengths of CRISPRi-mediated knockdowns in Vibrio natriegens using gRNA libraries

Stukenberg, D.; Faber, A.; Becker, A.

10.1101/2024.01.29.577714 — synthetic biology — Posted on 2024-01-29

483 Sequence-function mapping of proline-rich antimicrobial peptides

Collins, J.; McConnell, A.; Schmitz, Z.; Hackel, B. J.

10.1101/2024.01.28.577586 — synthetic biology — Posted on 2024-01-29

484 Physcomitrium patens flavodiiron proteins form a redox-dependent heterocomplex.

Beraldo, C.; Traverso, E.; Boschin, M.; Cendron, L.; Morosinotto, T.; Alboresi, A.

10.1101/2024.01.29.577648 — plant biology — Posted on 2024-01-29

485 Genetic mapping of the powdery mildew resistance gene Pm13 on oat chromosome 1D

Schurack, S.; Beuch, S.; Cowan, S.; Griffiths, I.; Lunzer, M.; Morales, L.; Tudor, S.; Buerstmayr, H.; Howarth, C. J.; Tinker, N. A.; Herrmann, M. H.

10.1101/2024.01.26.576824 — plant biology — Posted on 2024-01-29

486 Induction of common bean OVATE Family Protein 7 (PvOFP7) promotes resistance to common bacterial blight

Gaudin, C.; Preveaux, A.; Aubineau, N.; Le Goff, D.; Jacques, M.-A.; Chen, N. W. G.

10.1101/2024.01.26.577399 — plant biology — Posted on 2024-01-29

487 The EGF/EGFR-YAP1/TEAD2 axis-mediated BRAF inhibitor vemurafenib resistance upregulates STIM1 in melanoma

Bai, W.; Yan, C.; Yang, Y.; Sang, L.; Hao, Q.; Yao, X.; Yu, J.; Wang, Y.; Li, X.; Meng, M.; Yang, J.; Shen, J.; Sun, Y.; Sun, J.

10.1101/2024.01.29.577717 — cancer biology — Posted on 2024-01-29

488 Language models enable zero-shot prediction of RNA secondary structures including pseudoknots

Gong, T.; Bu, D.

10.1101/2024.01.27.577533 — bioinformatics — Posted on 2024-01-29

489 Quantifying the thermal tolerance traits of individual corals reveals widespread variation across the Great Barrier Reef

DENIS, H.; Bay, L. K.; Mocellin, V. J. L.; Naugle, M. S.; Lecellier, G.; Purcell, S. W.; Berteaux-Lecellier, V.; Howells, E. J.

10.1101/2024.01.28.576773 — ecology — Posted on 2024-01-29

490 Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modelling

Ryan, M.; McDonough, J. A.; Ward, M. E.; Cookson, M. R.; Skarnes, W. C.; Merkle, F. T.

10.1101/2024.01.29.577739 — cell biology — Posted on 2024-01-29

491 Characterization of the placenta-specific EnvV2-Fca soluble protein derived from endogenous retrovirus

Pramono, D.; Sugimoto, K.; Kimura, T.; Miyake, A.; Nishigaki, K.

10.1101/2024.01.28.577663 — microbiology — Posted on 2024-01-29

492 Wild Patagonian yeast improve the evolutionary potential of novel interspecific hybrid strains for Lager brewing

Molinet, J.; Navarrete, J. P.; Villarroel, C. A.; Villarreal, P.; Sandoval, F. I.; Nespolo, R. F.; Stelkens, R.; Cubillos, F. A.

10.1101/2024.01.29.577692 — microbiology — Posted on 2024-01-29

493 Comparative transcriptome analysis provides insights into the resistance regulation mechanism and inhibitory effect of fungicide phenamacril in Fusarium asiaticum

Zheng, Z.; Liu, H.; Luo, X.; Liu, R.; Joe, A.; Li, H.; Sun, H.; Yanling, L.; Li, Y.; Wang, Y.

10.1101/2024.01.29.577693 — pathology — Posted on 2024-01-29

494 Persister cancer cells are characterized by H4K20me3 heterochromatin that defines a low inflammatory profile

Ramponi, V.; Richart, L.; Kovatcheva, M.; Stephan-Otto Attolini, C.; Capellades, J.; Lord, A. E.; Yanes, O.; Ficz, G.; Serrano, M.

10.1101/2024.01.26.577389 — cancer biology — Posted on 2024-01-29

495 ListPred: A predictive ML tool for virulence potential and disinfectant tolerance in Listeria monocytogenes

Gmeiner, A.; Ivanova, M.; Kaas, R. S.; Xiao, Y.; Otani, S.; Leekitcharoenphon, P.

10.1101/2024.01.29.577690 — bioinformatics — Posted on 2024-01-29

496 Low-coverage whole genome sequencing for a highly selective cohort of severe COVID-19 patients

Santos, R.; Moreno-Torres, V.; Pintos, I.; Corral, O.; de Mendoza, C.; Soriano, V.; Corpas, M.

10.1101/2024.01.28.577610 — bioinformatics — Posted on 2024-01-29

497 Optimisation of the extraction process of naringin dihydrochalcone and its effect on reducing blood lipid levels in vitro

Yu, X.; Tian, M.-y.; Li, S.-q.; Qi, J.-w.; Zhang, L.

10.1101/2024.01.28.577672 — biochemistry — Posted on 2024-01-29

498 Xylan inhibition of cellulase binding and processivity observed at single-molecule resolution

Zexer, N.; Paradiso, A.; Nong, D.; Haviland, Z. K.; Hancock, W. O.; Anderson, C. T.

10.1101/2024.01.29.577775 — biochemistry — Posted on 2024-01-29

499 Multiple layers of innate immune response antagonism of SARS-CoV-2

Zhou, F.; Periasamy, S.; Jackson, N.; Cheng, W. S.; Soto Acosta, R.; Ilinykh, P.; Ye, C.; Chauhan, S.; Nudelman, G.; Zaslavsky, E.; Widen, S.; Martinez-Sobrido, L.; Sealfon, S.; Bukreyev, A.

10.1101/2024.01.29.577695 — microbiology — Posted on 2024-01-29

500 Discovery of orally active SARS-CoV-2 papain-like protease (PLpro) inhibitors

Garnsey, M. R.; Robinson, M. C.; Nguyen, L. T.; Cardin, R.; Tillotson, J.; Mashalidis, E.; Aijia, Y.; Aschenbrenner, L.; Balesano, A.; Behzadi, A.; Boras, B.; Chang, J. S.; Eng, H.; Ephron, A.; Foley, T.; Ford, K.; Frick, J. M.; Gibson, S.; Li, H.; Hurst, B.; Kalgutkar, A. S.; Korczynska, M.; Lengyel-Zhand, Z.; Liping, G.; Meredith, H. R.; Patel, N. C.; Polivkova, J.; Rai, D.; Rose, C. R.; Rothan, H.; Sakata, S. K.; Vargo, T. R.; Qi, W.; Wu, H.; Liu, Y.; Yurgelonis, I.; Zhang, J.; Zhu, Y.; Zhang, L.; Lee, A. A.

10.1101/2024.01.26.577395 — microbiology — Posted on 2024-01-29

501 Trade-off Between Resistance and Persistence in High Cell Density Escherichia Coli Cultures

Beulig, F.; Bafna-Ruehrer, J.; Jensen, P. E.; Kim, S. H.; Patel, A.; Kandasamy, V.; Steffen, C.; Decker, K.; Zielinski, D. C.; Yang, L.; Oezdemir, E.; Sudarsan, S.; Palsson, B. O.

10.1101/2024.01.29.575348 — microbiology — Posted on 2024-01-29

502 Mechanism of bacterial predation via ixotrophy

Lien, Y.-W.; Amendola, D.; Lee, K. S.; Bartlau, N.; Xu, J.; Furusawa, G.; Polz, M. F.; Stocker, R.; Weiss, G. L.; PIlhofer, M.

10.1101/2024.01.29.577165 — microbiology — Posted on 2024-01-29

503 SKSR1 identified as key virulence factor in Cryptosporidium by genetic crossing

He, W.; Sun, L.; Hou, T.; Yang, Z.; Yang, F.; Zhang, S.; Wang, T.; Li, N.; Guo, Y.; Sibley, L. D.; Feng, Y.; Xiao, L.

10.1101/2024.01.29.577707 — microbiology — Posted on 2024-01-29

504 A video-rate hyperspectral camera for monitoring plant health and biodiversity

Brooks, L. J.; Pearce, D.; Kwok, K.; Jawade, N.; Qi, M.; Fenollosa, E.; Beker, D.; Whicker, J.; Davis, K.; Salguero-Gomez, R.; Wang, R.; Chappell, S.

10.1101/2024.01.18.576183 — ecology — Posted on 2024-01-29

505 MEDIATOR SUBUNIT 25 modulates ERFVII-controlled hypoxia responses in Arabidopsis

Schippers, J.; von Bongartz, K.; Laritzki, L.; Frohn, S.; Frings, S.; Renziehausen, T.; Augstein, F.; Winkels, K.; Sprangers, K.; Sasidharan, R.; Vertommen, D.; van Breusegem, F.; Hartman, S.; Beemster, G. T. S.; Mhamdi, A.; van Dongen, J. T.; Schmidt-Schippers, R.

10.1101/2024.01.26.577166 — plant biology — Posted on 2024-01-29

506 Combining machine learning algorithms and single-cell data to study the pathogenesis of Alzheimer's disease

Xie, L. G.; Cui, W.; Lee, E.

10.1101/2024.01.26.577320 — bioinformatics — Posted on 2024-01-29

507 optimalTAD: annotation of topologically associating domains based on chromatin marks enrichment

Smirnov, D.; Kononkova, A.; Toiber, D.; Gelfand, M.; Khrameeva, E.

10.1101/2023.03.06.531254 — bioinformatics — Posted on 2024-01-29

508 10x Genomics Gene Expression Flex is a powerful tool for single-cell transcriptomics of xenograft models

Llora-Batlle, O.; Farcas, A.; Fransen, D.; Floch, N.; Talbot, S.; Schwiening, A.; Bojko, L.; Calver, J.; Josipovic, N.; Lashuk, K.; Schueler, J.; Prodan, A.; Mooijman, D.; McDermott, U.; PERSIST-SEQ Consortium,

10.1101/2024.01.25.577066 — genomics — Posted on 2024-01-29

509 ALS-associated FUS mutation reshapes the RNA and protein composition of Stress Granules.

Mariani, D.; Setti, A.; Castagnetti, F.; Vitiello, E.; Mecarelli, L. S.; Di Timoteo, G.; Giuliani, A.; Perego, E.; Zappone, S.; Liessi, N.; Armirotti, A.; Vicidomini, G.; Bozzoni, I.

10.1101/2023.09.11.557245 — molecular biology — Posted on 2024-01-29

510 Cytotoxic CD4+ T cells in the bone marrow compromise healthy ageing by enhancing granulopoiesis

Gabande-Rodriguez, E.; Soto-Heredero, G.; Carrasco, E.; Anerillas, C.; Escrig-Larena, J. I.; Delgado-Pulido, S.; Francos-Quijorna, I.; Gomez de las Heras, M. M.; Fernandez-Almeida, A.; Blanco, E. M.; Winand-Osete, E.; Zorita, V.; Martinez-Cano, J.; Garrido, A.; de Cabo, R.; Manes, S.; Gorospe, M.; Mittelbrunn, M.

10.1101/2024.01.26.577360 — immunology — Posted on 2024-01-29

511 Disentangling the effects of hearing loss and age on amplitude modulation frequency selectivity

Regev, J.; Relano-Iborra, H.; Zaar, J.; Dau, T.

10.1101/2023.07.15.549131 — neuroscience — Posted on 2024-01-29

512 Investigating the mechanism of chloroplast singlet oxygen signaling in the Arabidopsis thaliana accelerated cell death 2 mutant

Lemke, M. D.; Abate, A. N.; Woodson, J. D.

10.1101/2024.01.25.577309 — plant biology — Posted on 2024-01-29

513 On the relationship between afterimages and a simple sensorimotor reaction

Kulakov, A. A.

10.1101/2024.01.23.576541 — physiology — Posted on 2024-01-29

514 The spatial structure of the tumor immune microenvironment can explain and predict patient response in high-grade serous carcinoma

Van Kleunen, L. B.; Ahmadian, M.; Post, M. D.; Wolsky, R. J.; Rickert, C.; Jordan, K.; Hu, J.; Richer, J. K.; Marjon, N. A.; Behbakht, K.; Sikora, M. J.; Bitler, B. G.; Clauset, A.

10.1101/2024.01.26.577350 — cancer biology — Posted on 2024-01-29

515 Unveiling the role of SRY in male-biased cancers: Insights into the molecular basis of sex disparities in high-grade glioma and melanoma

Guardia, G. D. A.; Batista, R. L.; Penalva, L. O.; Galante, P. A. F.

10.1101/2023.07.14.548747 — cancer biology — Posted on 2024-01-29

516 A method for mining condition-specific co-expressed genes in Camellia sinensis based on K-means clustering: A case study of "Anji Baicha" tea cultivar

Zheng, X.; Lim, P. K.; Mutwil, M.; Wang, Y.

10.1101/2024.01.25.577317 — bioinformatics — Posted on 2024-01-29

517 Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data.

Gabriel, A. A.; Racle, J.; Falquet, M.; Jandus, C.; Gfeller, D.

10.1101/2023.10.11.561826 — bioinformatics — Posted on 2024-01-29

518 AutoPeptideML: Automated Machine Learning for Building Trustworthy Peptide Bioactivity Predictors

Fernandez-Diaz, R.; Cossio-Perez, R.; Agoni, C.; Hoang, L. T.; Lopez, V.; Shields, D. C.

10.1101/2023.11.13.566825 — bioinformatics — Posted on 2024-01-29

519 Information-Distilled Generative Label-Free Morphological Profiling Encodes Cellular Heterogeneity

Lo, M. C. K.; Siu, D. M. D.; Lee, K. C. M.; Wong, J. S. J.; Yeung, M. C. F.; Hsin, M. K. Y.; Ho, J. C. M.; Tsia, K. K.

10.1101/2023.11.06.565732 — bioengineering — Posted on 2024-01-29

520 A novel approach for simultaneous detection of structural and single-nucleotide variants based on a combination of chromosome conformation capture and exome sequencing

Gridina, M.; Lagunov, T.; Belokopytova, P.; Torgunakov, N.; Nuriddinov, M.; Nurislamov, A.; Nazarenko, L.; Kashevarova, A.; Lopatkina, M.; Belyaeva, E.; Salyukova, O.; Cheremnykh, A.; Suhanova, N.; Minzhenkova, M.; Markova, Z.; Demina, N.; Stepanchuk, Y.; Khabarova, A.; Yan, A.; Valeev, E.; Koksharova, G.; Grigoreva, E.; Kokh, N.; Lukjanova, T.; Maximova, Y.; Musatova, E.; Shabanova, E.; Kechin, A.; Khrapov, E.; Boyarskih, U.; Ryzhkova, O.; Suntsova, M.; Matrosova, A.; Karoli, M.; Manakhov, A.; Filipenko, M.; Rogaev, E.; Shilova, N.; Lebedev, I.; Fishman, V.

10.1101/2024.01.26.577292 — genomics — Posted on 2024-01-29

521 Mast fruiting in a large tropical African legume tree provides evidence for the nutrient resource limitation hypothesis

Newbery, D. M.; Schwan, S.; Chuyong, G. B.; Neba, G. A.; Etta, C. E.; Norghauer, J. M.; Worbes, M.

10.1101/2023.04.03.535348 — ecology — Posted on 2024-01-29

522 D2/D3 dopamine supports the precision of mental state inferences and self-relevance of joint social outcomes

Barnby, J. M.; Bell, V.; Deeley, Q.; Mehta, M. A.; Moutoussis, M. M.

10.1101/2023.05.02.539031 — neuroscience — Posted on 2024-01-29

523 Acute toxicity effects of pesticides on beneficial organisms - Dispelling myths for a more sustainable use of chemicals in agricultural environments

Mata, L.; Knapp, R. A.; McDougall, R.; Overton, K.; Hoffmann, A. A.; Umina, P. A.

10.1101/2024.01.25.577310 — pharmacology and toxicology — Posted on 2024-01-29

524 Comparative transcriptome database for Camellia sinensis reveals genes important for flavonoid synthesis in tea plants

Zheng, X.; Mohd Ali, Z.; Lim, P. K.; Mutwil, M.; Wang, Y.

10.1101/2024.01.25.577142 — bioinformatics — Posted on 2024-01-29

525 Romer-EPTI: Rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale dMRI and microstructure imaging

Dong, Z.; Reese, T. G.; Lee, H.-H.; Huang, S. Y.; Polimeni, J. R.; Wald, L. L.; Wang, F.

10.1101/2024.01.26.577343 — bioengineering — Posted on 2024-01-29

526 Why the brown ghost chirps at night

Oboti, L.; Pedraja, F.; Ritter, M.; Lohse, M.; Klette, L.; Krahe, R.

10.1101/2022.12.29.522225 — animal behavior and cognition — Posted on 2024-01-29

527 Evaluation of Autophagy in conjunctival fibroblasts

Mehrbod, P.; Brun, P.; Rosani, U.; Leonardi, A.; Ghavami, S.

10.1101/2024.01.27.575831 — cell biology — Posted on 2024-01-29

528 Prestimulus alpha phase modulates visual temporal integration

Johannknecht, M.; Schnitzler, A.; Lange, J.

10.1101/2024.01.29.577737 — neuroscience — Posted on 2024-01-29

529 DMT induces a transient destabilization of whole-brain dynamics

Piccinini, J.; Sanz Perl, Y.; Pallavicini, C.; Deco, G.; Kringelbach, M. L.; Nutt, D.; Carhart-Harris, R.; Timmermann, C.; Tagliazucchi, E.

10.1101/2024.01.26.577435 — neuroscience — Posted on 2024-01-29

530 Evidence for interacting but decoupled controls of decisions and movements in non-human primates

Saleri, C.; Thura, D.

10.1101/2024.01.29.577721 — animal behavior and cognition — Posted on 2024-01-29

531 Expression patterns of FGF and BMP pathway genes in the tardigrade Hypsibius exemplaris

Heikes, K. L.; Goldstein, B.

10.1101/2024.01.29.577774 — developmental biology — Posted on 2024-01-29

532 Polycomb Repressive Complex 1.1 Component, BCOR, Promotes Syncytiotrophoblast Differentiation in Mice and Humans

Sadowski, D.; Corcoran, C. M.; Abdi, R.; Zheng, T.; Okae, H.; Arima, T.; Bardwell, V. J.; Gearhart, M. D.

10.1101/2024.01.29.577740 — developmental biology — Posted on 2024-01-29

533 Global MEG Resting State Functional Connectivity in Children with Autism and Sensory Processing Dysfunction

Demopoulos, C.; Jesson, X.; Molly, G. R.; Jurigova, B.; Hinkley, L.; Ranasinghe, K. G.; Desai, S.; Honma, S.; Mizuiri, D.; Findlay, A.; Nagarajan, S.; Marco, E.

10.1101/2024.01.26.577499 — neuroscience — Posted on 2024-01-29

534 Decreasing ganglioside synthesis delays motor and cognitive symptom onset in Spg11 knockout mice

Fortier, M.; Cauhape, M.; Buono, S.; Becker, J.; Menuet, A.; Branchu, J.; Ricca, I.; Mero, S.; Dorgham, K.; El Hachimi, K. H.; Dobrenis, K.; Colsch, B.; Samaroo, D.; Devaux, M.; Durr, A.; Stevanin, G.; Santorelli, F. M.; Colombo, S.; Cowling, B.; Darios, F.

10.1101/2024.01.29.577736 — neuroscience — Posted on 2024-01-29

535 Predicting social experience from dyadic interaction dynamics: the BallGame, a novel paradigm to study social engagement

Luebbert, A.; Sengelmann, M.; Heimann, K.; Schneider, T. R.; Engel, A. K.; Goeschl, F.

10.1101/2024.01.26.577035 — neuroscience — Posted on 2024-01-29

536 Encoding of vibrotactile stimuli by mechanoreceptors in rodent glabrous skin

Medlock, L.; Al Basha, D.; Halawa, A.; Dedek, C.; Ratte, S.; Prescott, S. A.

10.1101/2024.01.29.577766 — neuroscience — Posted on 2024-01-29

537 Drawings reveal changes in object memory, but not spatial memory, across time

Megla, E.; Rosenthal, S. R.; Bainbridge, W. A.

10.1101/2024.01.26.577281 — neuroscience — Posted on 2024-01-29

538 Frontal-Auditory Cortical Interactions and Sensory Prediction During Vocal Production in Marmoset Monkeys

Tsunada, J.; Eliades, S. J.

10.1101/2024.01.28.577656 — neuroscience — Posted on 2024-01-29

539 Rapid and objective assessment of auditory temporal processing using dynamic amplitude-modulated stimuli

Parida, S.; Yurasits, K.; Cancel, V. E.; Zink, M. E.; Mitchell, C.; Ziliak, M. C.; Harrison, A. V.; Bartlett, E. L.; Parthasarathy, A.

10.1101/2024.01.28.577641 — neuroscience — Posted on 2024-01-29

540 Long-term mouse spinal cord organotypic slice culture as a platform for validating cell transplantation in spinal cord injury

Merighi, F.; De Vincentiis, S.; Onorati, M.; Raffa, V. S.

10.1101/2024.01.29.577615 — neuroscience — Posted on 2024-01-29

541 Modelling variability in dynamic functional brain networks using embeddings

Huang, R.; Gohil, C.; Woolrich, M. W.

10.1101/2024.01.29.577718 — neuroscience — Posted on 2024-01-29

542 Non-contact detection of pyrethroids widely used in vector control by Anopheles mosquitoes

KAMBOU, S. S.; VALENTE, A.; AGNEW, P.; Hien, D. F. d. S.; YERBANGA, R. S.; MOIROUX, N.; DABIRE, K. R.; PENNETIER, C.; COHUET, A.; CARRASCO, D.

10.1101/2024.01.28.577675 — animal behavior and cognition — Posted on 2024-01-29

543 The nunatak and tabula rasa hypotheses may be compatible: the European phylogeography of a riparian earthworm.

de Sosa, I.; Marchan, D. F.; Erseus, C.; Lapied, E.; Jelic, M.; Jablonska, A.; Szederjesi, T.; Almodovar, A.; Novo, M.; Diaz Cosin, D. J.

10.1101/2024.01.26.576623 — zoology — Posted on 2024-01-29

544 SignalingProfiler 2.0: a network-based approach to bridge multi-omics data to phenotypic hallmarks

Venafra, V.; Sacco, F.; Perfetto, L.

10.1101/2024.01.25.577229 — systems biology — Posted on 2024-01-29

545 Shoring up the base: the development and regulation of cortical sclerenchyma in grass nodal roots

McCahill, I. W.; Khahani, B.; Probert, C. F.; Flockhart, E. L.; Abushal, L. T.; Gregory, G. A.; Zhang, Y.; Baumgart, L. A.; O'Malley, R. C.; Hazen, S. P.

10.1101/2024.01.25.577257 — plant biology — Posted on 2024-01-29

546 Morphological and genetic analysis of inflorescence and flower development in hemp (Cannabis sativa L.)

Shi, J.; Schilling, S.; Melzer, R.

10.1101/2024.01.25.577276 — plant biology — Posted on 2024-01-29

547 Undoing the 'nasty: dissecting touch-sensitive stigma movement (thigmonasty) and its loss in self-pollinating monkeyflowers

Fishman, L.; McIntosh, M.; Nelson, T. C.; Baesen, K.; Finseth, F. R.; Stark-dykema, E.

10.1101/2024.01.25.577247 — plant biology — Posted on 2024-01-29

548 Ligand supplementation restores the cancer therapy efficacy of an antirheumatic drug auranofin from serum inactivation

Wang, Y.; Cao, B.; Wang, Q.; Fang, X.; Wang, J.; Chan, A. S. C.; Xiong, X.; Zou, T.

10.1101/2024.01.25.577173 — cancer biology — Posted on 2024-01-29

549 Synthetic Histology Images for Training AI Models: A Novel Approach to Improve Prostate Cancer Diagnosis

Van Booven, D. J.; Chen, C.-B.; Kryvenko, O.; Punnen, S.; Sandoval, V.; Malpani, S.; Noman, A.; Ismael, F.; Briseno, A.; Wang, Y.; Arora, H.

10.1101/2024.01.25.577225 — cancer biology — Posted on 2024-01-29

550 A Biophysical Model for ATAC-seq Data Analysis

Gorin, G.; Pachter, L.; Felce, C.

10.1101/2024.01.25.577262 — bioinformatics — Posted on 2024-01-29

551 Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue

Daucke, R.; Rift, C. V.; Bager, N. S.; Saxena, K.; Koffeldt, P. R.; Woessmann, J.; Petrosius, V.; Rugiu, E. S.; Kristensen, B. W.; Klausen, P.; Schoof, E. M.

10.1101/2024.01.25.577263 — bioengineering — Posted on 2024-01-29

552 Unlocking genome-based prediction and selection in conifers: the key role of within-family prediction accuracy

Papin, V.; Gorjanc, G.; Pocrnic, I.; Bouffier, L.; Sanchez, L.

10.1101/2024.01.25.577259 — genomics — Posted on 2024-01-29

553 Harnessing Stress: balancing the Burden of Slightly-Deleterious Variants by a Handicap

Shamanskiy, V. A.; Popadin, K. Y.

10.1101/2024.01.25.577025 — genetics — Posted on 2024-01-29

554 Analyzing the intrastate and interstate swine movement network in the United States

Cardenas, N. C.; Valencio, A. L. S.; Sanchez, F.; OHara, K. C.; Machado, G.

10.1101/2024.01.25.576551 — ecology — Posted on 2024-01-29

555 Repulsion from slow-diffusing nutrients improves chemotaxis towards moving sources

Bloxham, B.; Lee, H.; Gore, J.

10.1101/2024.01.25.577248 — ecology — Posted on 2024-01-29

556 Studying the cellular basis of small bowel enteropathy using high-parameter flow cytometry in mouse models of primary antibody deficiency

Mohammed, A. D.; Ball, R. A. W.; Jolly, A.; Nagarkatti, P.; Nagarkatti, M.; Kubinak, J. L.

10.1101/2024.01.25.577009 — immunology — Posted on 2024-01-29

557 Viral antigen mismatch affects antiviral T-cell response and may impair immunotherapeutic efficacy against ATL

Sugata, K.; Takatori, M.; Reda, O.; Tan, B. J. Y.; Tokunaga, M.; Sato, T.; Ueda, M.; Yamano, Y.; Utsunomiya, A.; Satou, Y.

10.1101/2024.01.25.576615 — immunology — Posted on 2024-01-29

558 Hexose transporters CsHT3/16 involved in post-phloem transport and affected cucumber fruit development

Cheng, J.; Wen, S.; Li, K.; Zhou, Y.; Zhu, M.; Neuhaus, H. E.; Bie, Z.

10.1101/2024.01.25.577232 — physiology — Posted on 2024-01-29

559 Logistic resource limitation model for quasi real-time measured subjective cognitive load predicts Hill function of hemoglobin-oxygen saturation

Furstenau, N.

10.1101/2024.01.23.576976 — biophysics — Posted on 2024-01-29

560 Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus

Ketaren, N. E.; Mast, F. D.; Fridy, P. C.; Olivier, J. P.; Sanyal, T.; Sali, A.; Chait, B. T.; Rout, M. P.; Aitchison, J.

10.1101/2023.07.14.549041 — biochemistry — Posted on 2024-01-29

561 Tracing 600 years of long-distance Atlantic cod trade in medieval and post-medieval Oslo using stable isotopes and ancient DNA

Martinez Garcia, L.; Pulido, A.; Ferrari, G.; Hufthammer, A. K.; Vedeler, M.; Hirons, A.; Kneale, C.; Barrett, J. H.; Star, B.

10.1101/2024.01.25.577044 — ecology — Posted on 2024-01-29

562 Learning predictive signatures of HLA type from T-cell repertoires

Ortega, M. R.; Pogorelyy, M.; Minervina, A.; Thomas, P.; Walczak, A.; Mora, T.

10.1101/2024.01.25.577228 — immunology — Posted on 2024-01-29

563 The integrated stress response/eIF2α pathway controls cytokine production in tissue-resident memory CD4+ T cells

Asada, N.; Ginsberg, P.; Paust, H.-J.; Song, N.; Riedel, J.-H.; Turner, J.-E.; Peters, A.; Kaffke, A.; Engesser, J.; Wang, H.; Zhao, Y.; Gild, P.; Dahlem, R.; Das, S.; Ignatova, Z.; Huber, T. B.; Prinz, I.; Gagliani, N.; Mittruecker, H.-W.; Krebs, C. F.; Panzer, U.

10.1101/2024.01.26.577246 — immunology — Posted on 2024-01-29

564 Student experiences with an interactive 3D immersive biotechnology simulation and its impact on motivational beliefs

Spencer, D.; McKeown, C.; Tredwell, D.; Huckaby, B.; Wiedner, A.; Dums, J. T.; Cartwright, E. L.; Potts, C. M.; Sudduth, N. C.; Brown, E.; Albright, P.; Jhala, A.; Srougi, M. C.

10.1101/2024.01.23.576860 — scientific communication and education — Posted on 2024-01-29

565 The interplay between dormant mutated cells and tumor promotion by chronic tissue damage in determining cancer risk.

Li, Y. R.; Kandyba, E.; Halliwill, K.; Delrosario, R.; Tran, Q.; Bayani, N.; Wu, D.; Mirzoeva, O.; Reeves, M. M.; Islam, M.; Riva, L.; Bergstrom, E. N.; Achanta, K.; Digiovanni, J.; Alexandrov, L.; Balmain, A.

10.1101/2024.01.24.577147 — cancer biology — Posted on 2024-01-29

566 Restoring O-glycosylation and expression of MUC2 limits progression of colorectal cancer

Yang, Y.; Yin, Y.; Xu, W.; Kang, Y.; Chen, J.; Zou, Y.; Xiao, Z.; Li, Z.; Cao, P.

10.1101/2024.01.25.577208 — cancer biology — Posted on 2024-01-29

567 Development of non-sedating antischistosomal benzodiazepines

Mian, M. Y.; Sharmin, D.; Mondal, P.; Belayet, J. B.; Hossain, M. M.; McCusker, P.; Ryan, K. T.; Fedorov, A. Y.; Green, H. A.; Ericksen, S. S.; Zamanian, M.; Phani Babu Tiruveedhula, V. V. N.; Cook, J. M.; Chan, J. D.

10.1101/2024.01.26.577323 — pharmacology and toxicology — Posted on 2024-01-29

568 They all rock: A systematic comparison of conformational movements in LeuT-fold transporters

Licht, J. A.; Berry, S. P.; Gutierrez, M. A.; Gaudet, R.

10.1101/2024.01.24.577062 — biophysics — Posted on 2024-01-29

569 Super-resolved protein imaging using bifunctional light-up aptamers

Grun, F.; van den Bergh, N.; Klevanski, M.; Verma, M. S.; Buhler, B.; Nienhaus, G. U.; Kuner, T.; Jaschke, A.; Sunbul, M.

10.1101/2024.01.26.577321 — biophysics — Posted on 2024-01-29

570 Spatiotemporal Modeling of Mitochondrial Network Architecture

Holt, K.; Winter, J.; Manley, S.; Koslover, E. F.

10.1101/2024.01.24.577101 — biophysics — Posted on 2024-01-29

571 AdhE spirosome length in enterohaemorrhagic Escherichia coli is correlated with enzymatic directionality and is perturbed by salicylidene acylhydrazide binding

Serrano, E.; Tyler, A. I. I.; Soroor, M.; Floria, I.; Kapur, N.; Roe, A. J.; Byron, O.

10.1101/2024.01.25.577206 — biophysics — Posted on 2024-01-29

572 MuPET-Flow: Multiple Ploidy Estimation Tool from Flow cytometry data

Gomez-Munoz, C.; Fischer, G.

10.1101/2024.01.24.577056 — bioinformatics — Posted on 2024-01-29

573 scATAcat: Cell-type annotation for scATAC-seq data

Altay, A.; Vingron, M.

10.1101/2024.01.24.577073 — bioinformatics — Posted on 2024-01-29

574 Comparative Analysis of Biomarkers in Type 2 Diabetes Patients with and without Comorbidities: Insights into the Role of Hypertension and Cardiovascular Disease

SAVVOPOULOS, S. V.; Hatzikirou, H.; Jelinek, H.

10.1101/2024.01.25.577186 — bioinformatics — Posted on 2024-01-29

575 Deep Learning Outperforms Classical Machine Learning Methods in Pediatric Brain Tumor Classification through Mass Spectra

Santos Bezerra, T. M.; Silva de Deus, M.; Cavalaro, F.; Ribeiro, D.; Seidinger, A. L.; Cardinalli, I.; Porcari, A.; Pedrini, H.; Meidanis, J.

10.1101/2024.01.24.577095 — bioinformatics — Posted on 2024-01-29

576 Optimizing Accuracy and Efficiency in Analyzing Non-UMI Liquid Biopsy Datasets Using the Sentieon ctDNA Pipeline

Niu, L.; Hu, J.; Chen, C.; Jiang, C.; Chen, H.; Tang, G.; Liu, Y.; Liu, Y.

10.1101/2024.01.24.577136 — bioinformatics — Posted on 2024-01-29

577 Transverse Aortic COnstriction Multi-omics Analysis (TACOMA) uncovers pathophysiological cardiac molecular mechanisms

Gjerga, E.; Dewenter, M.; Britto-Borges, T.; Grosso, J.; Stein, F.; Eschenbach, J.; Rettel, M.; Backs, J.; Dieterich, C.

10.1101/2024.01.26.577333 — bioinformatics — Posted on 2024-01-29

578 MORE interpretable multi-omic regulatory networks to characterize phenotypes

Aguerralde-Martin, M.; Clemente-Ciscar, M.; Lopez-Carcel, L.; Conesa, A.; Tarazona, S.

10.1101/2024.01.25.577162 — bioinformatics — Posted on 2024-01-29

579 Optimal Phylogenetic Reconstruction of Insertion and Deletion Events

Tule, S.; Foley, G.; Zhao, C.; Forbes, M.; Boden, M.

10.1101/2024.01.24.577130 — bioinformatics — Posted on 2024-01-29

580 Polarity-JaM: An image analysis toolbox for cell polarity, junction and morphology quantification

Giese, W.; Albrecht, J. P.; Oppenheim, O.; Akmeric, E. B.; Kraxner, J.; Schmidt, D.; Harrington, K. I.; Gerhardt, H.

10.1101/2024.01.24.577027 — bioinformatics — Posted on 2024-01-29

581 CODEX: COunterfactual Deep learning for the in-silico EXploration of cancer cell line perturbations

Schrod, S.; Zacharias, H. U.; Beissbarth, T.; Hauschild, A.-C.; Altenbuchinger, M. C.

10.1101/2024.01.24.577020 — bioinformatics — Posted on 2024-01-29

582 scMulan: a multitask generative pre-trained language model for single-cell analysis

Bian, H.; Chen, Y.; Dong, X.; Li, C.; Hao, M.; Chen, S.; Hu, J.; Sun, M.; Wei, L.; Zhang, X.

10.1101/2024.01.25.577152 — bioinformatics — Posted on 2024-01-29

583 Phylogenetic tree statistics: a systematic overview using the new R package 'treestats'

Janzen, T.; Etienne, R. S.

10.1101/2024.01.24.576848 — bioinformatics — Posted on 2024-01-29

584 Uncovering functional lncRNAs by scRNA-seq with ELATUS

Goni, E.; Mas, A. M.; Abad, A.; Santisteban, M.; Fortes, P.; Huarte, M.; Hernaez, M.

10.1101/2024.01.26.577344 — bioinformatics — Posted on 2024-01-29

585 PERFORATION-TYPE ANCHORS INSPIRED BY SKIN LIGAMENT FOR THE ROBOTIC FACE COVERED WITH LIVING SKIN

Kawai, M.; Nie, M.; Oda, H.; Takeuchi, S.

10.1101/2024.01.24.576563 — bioengineering — Posted on 2024-01-29

586 Activated fibroblasts drive cellular interactions in end-stage pediatric hypertrophic cardiomyopathy

Tadros, H. J.; Turaga, D.; Zhao, Y.; Tsai, C.-R. J.; Adachi, I.; Li, X.; Martin, J. F.

10.1101/2024.01.25.577226 — genomics — Posted on 2024-01-29

587 Predicting the DNA binding specificity of mutated transcription factors using family-level biophysically interpretable machine learning

Liu, S.; Gomez-Alcala, P.; Leemans, C.; Glassford, W. J.; Mann, R. S.; Bussemaker, H. J.

10.1101/2024.01.24.577115 — genomics — Posted on 2024-01-29

588 Genetic and bioinformatic analyses reveal transcriptional networks underlying dual genomic coordination of mitochondrial biogenesis

Xu, H.

10.1101/2024.01.25.577217 — genetics — Posted on 2024-01-29

589 Somatic epigenetic drift during shoot branching: a cell lineage-based model

Chen, Y.; Burian, A.; Johannes, F.

10.1101/2024.01.24.577071 — genetics — Posted on 2024-01-29

590 Skewness enables stabilising effect of hierarchy in complex competition networks

Koch, F.; Neutel, A.-M.; Barnes, D. K.; Allhoff, K. T.

10.1101/2024.01.25.577181 — ecology — Posted on 2024-01-29

591 Realistic time-lags and litter dynamics alter predictions of plant-soil feedback across generations

Ou, S. X.; Kandlikar, G. S.; Warren, M. L.; Ke, P.-J.

10.1101/2024.01.25.577053 — ecology — Posted on 2024-01-29

592 Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy

Grunewald, L.; Andersch, L.; Helmsauer, K.; Schwiebert, S.; Klaus, A.; Henssen, A. G.; Straka, T.; Lodrini, M.; Wicha, S. G.; Fuchs, S.; Hertwig, F.; Westermann, F.; Vitali, A.; Caramel, C.; Buechel, G.; Eilers, M.; Astrahantseff, K.; Eggert, A.; Hoepken, U. E.; Schulte, J. H.; Blankenstein, T.; Anders, K.; Kuenkele, A.

10.1101/2024.01.27.576592 — immunology — Posted on 2024-01-29

593 Chronic Stress effects on Immune-Neuroendocrine matrix in Coturnix coturnix, analyses from an ontogenetic perspective

Marozzi, A.; Correa, S. G.; Palme, R.; Cantarelli, V. I.; Ponzio, M. F.; Marin, R. H.; Nazar, F. N.

10.1101/2024.01.24.577005 — physiology — Posted on 2024-01-29

594 High impact AMPAkines induce a Gq-protein coupled endoplasmic calcium release in cortical neurons: a possible mechanism for explaining the toxicity of high impact AMPAkines

Radin, D. P.; Zhong, S.; Cerne, R.; Witkin, J.; Lippa, A.

10.1101/2024.01.28.577446 — pharmacology and toxicology — Posted on 2024-01-29

595 Synaptic motility and functional stability in the whisker cortex

Sherf, N.; Shamir, M.

10.1101/2024.01.28.577661 — biophysics — Posted on 2024-01-29

596 Density dependence shapes life-history trade-offs in a food limited ungulate population

Jaggi, H.; ZUO, W.; Kentie, R.; Gaillard, J.-M.; Coulson, T.; Tuljapurkar, S. D.

10.1101/2024.01.26.577325 — ecology — Posted on 2024-01-29

597 Sounds of the underground reflect soil biodiversity dynamics across a grassy woodland restoration chronosequence

Robinson, J. M.; Taylor, A.; Fickling, N.; Sun, X.; Breed, M. F.

10.1101/2024.01.25.577311 — ecology — Posted on 2024-01-29

598 HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis

Xu, F.; Suyama, R.; Inada, T.; Kawaguchi, S.; Kai, T.

10.1101/2024.01.29.576963 — developmental biology — Posted on 2024-01-29

599 Local glycolysis supports injury-induced axonal regeneration

Masin, L.; Bergmans, S.; Van Dyck, A.; De Groef, L.; Farrow, K.; Moons, L.

10.1101/2024.01.29.577706 — neuroscience — Posted on 2024-01-29

600 Establishment of an easy-to-construct liver injury mouse model for longitudinal analysis by drinking-water administration of 4,4'-methylenedianiline

Iwasaka, T.; Mizuno, T.; Morita, K.; Azuma, I.; Nakagawa, T.; Nakashima, E.; Kusuhara, H.

10.1101/2024.01.25.577198 — pharmacology and toxicology — Posted on 2024-01-29

601 Islands of genomic stability in the face of genetically unstable metastatic cancer

Bowland, K.; Lai, J.; Skaist, A.; Zhang, Y.; Teh, S. S. K.; Roberts, N. J.; Thompson, E.; Wheelan, S. J.; Hruban, R. H.; Karchin, R.; Iacobuzio-Donahue, C. A.; Eshleman, J. R.

10.1101/2024.01.26.577508 — cancer biology — Posted on 2024-01-29

602 Oncogenic RAS signaling suppresses ferroptosis via transcriptional upregulation of GCH1

Lim, J. K.; Stoelting, F.; Levy, T.; Thewes, L.; Picard, D.; Tishina, S.; Zhang, H.-F.; Lewandowska, O.; Reiff, T.; Remke, M.; Braegelmann, J.; Beleggia, F.; Berndt, C.; von Karstedt, S.; Reifenberger, G.; Rotblat, B.; Leprivier, G.

10.1101/2024.01.27.577524 — cancer biology — Posted on 2024-01-29

603 MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model

Blackman, A.; Rees, A. C.; Bowers, R. R.; Jones, C. M.; Vaena, S. G.; Clark, M. A.; Carter, S.; Villamor, E.; Evans, D.; Emanuel, A. J.; Fullbright, G.; Long, D. T.; Spruill, L.; Romeo, M. J.; Helke, K. L.; Delaney, J. R.

10.1101/2024.01.24.576924 — cancer biology — Posted on 2024-01-29

604 Early-stage cancer results in a multiplicative increase in cell-free DNA originating from healthy tissue

Mamis, K.; Bozic, I.

10.1101/2024.01.26.577500 — cancer biology — Posted on 2024-01-29

605 Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression.

Amin, R.; Ha, N.-H.; Qiu, T.; Holewinski, R.; Lam, K. C.; Lopes, A.; Liu, H.; Tran, A. D.; Lee, M. P.; Gamage, S. T.; Andresson, T.; Goldszmid, R. S.; Meier, J. L.; Hunter, K.

10.1101/2024.01.24.577116 — cancer biology — Posted on 2024-01-29

606 SMARCD1 is a "Goldilocks" metastasis modifier

Ross, C. R.; Gong, L.-Y.; Jenkins, L. M.; Ha, N.-h.; Majocha, M.; Hunter, K.

10.1101/2024.01.24.577061 — cancer biology — Posted on 2024-01-29

607 Beyond comparison: Brillouin microscopy and AFM-based indentation reveal divergent insights into the mechanical profile of the murine retina

Möllmert, S.; Gutmann, M.; Müller, P.; Kim, K.; Bachir Salvador, J.; Aif, S.; Meinel, L.; Guck, J.

10.1101/2024.01.24.577013 — biophysics — Posted on 2024-01-29

608 Thoughtful faces: inferring internal states across species using facial features

Tlaie, A.; Abd El Hay, M. Y.; Mert, B.; Taylor, R.; Ferracci, P. A.; Shapcott, K. A.; Glukhova, M.; Pillow, J. W.; Havenith, M. N.; Scholvinck, M.

10.1101/2024.01.24.577055 — animal behavior and cognition — Posted on 2024-01-29

609 Transgenerational chromosome repair in the asexual bdelloid rotifer Adineta vaga

Houtain, A.; Derzelle, A.; Lliros, M.; Hespeels, B.; Nicolas, E.; Simion, P.; Virgo, J.; Heuskin, A.-C.; Lenormand, T.; Hallet, B.; Van Doninck, K.

10.1101/2024.01.25.577190 — evolutionary biology — Posted on 2024-01-29

610 Limited genomic signatures of population collapse in the critically endangered black abalone (Haliotis cracherodii)

Wooldridge, B.; Orland, C.; Enbody, E.; Escalona, M.; Mirchandani, C. D.; Corbett-Detig, R.; Kapp, J. D.; Fletcher, N.; Ammann, K.; Raimondi, P.; Shapiro, B.

10.1101/2024.01.26.577275 — evolutionary biology — Posted on 2024-01-29

611 Sex-biased migration and demographic history of the big European firefly Lampyris noctiluca

Catalan, A.; Gygax, D.; Candolin, U.; Tusso, S.; Duchen, P.; Hoehna, S.

10.1101/2024.01.24.577017 — evolutionary biology — Posted on 2024-01-29

612 Queen loss fails to elicit physiological and transcriptional responses in workers of the invasive garden ant Lasius neglectus

Majoe, M.; Stolarek, N.; Vizueta, J.; Xiong, Z.; Schrader, L.; Boomsma, J. J.; Foitzik, S.; Libbrecht, R.; Nehring, V.

10.1101/2024.01.26.577224 — evolutionary biology — Posted on 2024-01-29

613 High variability in the attractiveness of municipally-planted decorative plants to pollinators

Czaczkes, T. J.; Breuss, C.; Kurze, C.

10.1101/2024.01.25.577170 — ecology — Posted on 2024-01-29

614 A large-scale cancer-specific protein-DNA interaction network

Lu, Y.; Berenson, A.; Lane, R.; Guelin, I.; Li, Z.; Chen, Y.; Shah, S.; Yin, M.; Soto-Ugaldi, L. F.; Fiszbein, A.; Fuxman Bass, J. I.

10.1101/2024.01.24.577099 — systems biology — Posted on 2024-01-29

615 Single-Cell RNA-seq based elucidation of the antidepressant hyperforin biosynthesis de novo in St. John's wort.

Wu, S.; Morotti, A. L. M.; Yang, J.; Wang, E.; Tatsis, E. C.

10.1101/2024.01.24.577018 — plant biology — Posted on 2024-01-29

616 Hypoxia-induced Complement Component 3 Promotes Aggressive Tumor Growth in the Glioblastoma Microenvironment

Rosberg, R.; Smolag, K. I.; Sjolund, J.; Johansson, E.; Bergelin, C.; Wahlden, J.; Pantazopoulou, V.; Ceberg, C.; Pietras, K.; Blom, A. M.; Pietras, A.

10.1101/2024.01.28.577617 — cancer biology — Posted on 2024-01-29

617 Inhibition of ADAM17 increases cytotoxic effect of cisplatin in cervical spheroids and organoids

Holthaus, D.; Rogmans, C.; Gursinski, I.; Quevedo-Olmos, A.; Ehsani, M.; Mangler, M.; Floerkemeier, I.; Weimer, J. P.; Meyer, T. F.; Maass, N.; Bauerschlag, D. O.; Hedemann, N.

10.1101/2024.01.27.577547 — cancer biology — Posted on 2024-01-29

618 GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15

Chang, C.; Cheng, Y.-Y.; Kamlapurkar, S.; White, S. R.; Tang, P. W.; Elhaw, A. T.; Javed, Z.; Aird, K. M.; Mythreye, K.; Phaeton, R.; Hempel, N.

10.1101/2024.01.24.577037 — cancer biology — Posted on 2024-01-29

619 Stable Isotope Probing-nanoFTIR for Quantitation of Cellular Metabolism and Observation of Growth-dependent Spectral Features

Burr, D. J.; Drauschke, J.; Kanevche, K.; Kuemmel, S.; Stryhanyuk, H.; Heberle, J.; Perfumo, A.; Elsaesser, A.

10.1101/2024.01.24.576656 — biophysics — Posted on 2024-01-29

620 Using splines for point spread function calibration atnon-uniform depths in localization microscopy

Korovin, S.; Kalisvaart, D.; Hung, S.-T.; Cnossen, J.; de Visser, C.; Smith, C. S.

10.1101/2024.01.24.577007 — biophysics — Posted on 2024-01-29

621 On the annotation of Paleo- and Mesoproterozoic microfossils as fungi

Kanaparthi, D.; Lampe, M.; Krings, M.; Schue, B. S.; Klingl, A.; Schwille, P.; Lueders, T.

10.1101/2024.01.25.577314 — evolutionary biology — Posted on 2024-01-29

622 Dissecting endogeneous genetic circuits from first principles

Pan, R. W.; Roeschinger, T.; Faizi, K.; Phillips, R.

10.1101/2024.01.28.577658 — genomics — Posted on 2024-01-29

623 Formation of long-term memory without short-term memory by CaMKII inhibition

Shin, M. E.; Parra-Bueno, P.; Yasuda, R.

10.1101/2024.01.28.577644 — neuroscience — Posted on 2024-01-29

624 In vivo CRISPR screens identify novel virulence genes among proteins of unassigned subcellular localization in Toxoplasma

Tachibana, Y.; Sasai, M.; Yamamoto, M.

10.1101/2024.01.28.577556 — microbiology — Posted on 2024-01-29

625 Flexible gating between subspaces by a disinhibitory motif: a neural network model of internally guided task switching

Liu, Y.; Wang, X.-J.

10.1101/2023.08.15.553375 — neuroscience — Posted on 2024-01-28

626 S-PLM: Structure-aware Protein Language Model via Contrastive Learning between Sequence and Structure

Wang, D.; Pourmirzaei, M.; Abbas, U. L.; Zeng, S.; Manshour, N.; Esmaili, F.; Poudel, B.; Jiang, Y.; Shao, Q.; Chen, J.; Xu, D.

10.1101/2023.08.06.552203 — bioinformatics — Posted on 2024-01-28

627 The ion channel TRPM8 is a direct target of the immunosuppressant rapamycin in primary sensory neurons

Arcas, J. M.; Oudaha, K.; Gonzalez, A.; Fernandez-Trillo, J.; Peralta, F. A.; Castro-Marsal, J.; Poiraz, S.; Taberner, F.; Sala, S.; de la Pena, E.; Gomis, A.; Viana, F.

10.1101/2024.01.24.577111 — neuroscience — Posted on 2024-01-28

628 Uncovering the Roles of Mycobacterium tuberculosis melH in Redox and Bioenergetic Homeostasis: Implications for Antitubercular Therapy

Chen, Y.-c.; Yang, X.; Wang, N.; Sampson, N. S.

10.1101/2023.10.02.560593 — microbiology — Posted on 2024-01-28

629 Newly developing methodologies to investigate health hazards posed by ionizing radiation to human space missions

Ferrari, F.; Szuszkiewicz, E.

10.1101/2022.03.28.486099 — biophysics — Posted on 2024-01-28

630 Promoted extension of an epidermal cell by semaphorin in C. elegans revealed by a mosaic gene expression analysis by using the IR-LEGO single-cell gene induction system

Suzuki, M.; Takagi, S.

10.1101/2024.01.24.577022 — cell biology — Posted on 2024-01-28

631 In vivo CRISPR screens identify novel virulence genes among proteins of unassigned subcellular localization in Toxoplasma

Tachibana, Y.; Sasai, M.; Yamamoto, M.

10.1101/2024.01.28.577556 — microbiology — Posted on 2024-01-28

632 nf-core/airrflow: an adaptive immune receptor repertoire analysis workflow employing the Immcantation framework

Gabernet, G.; Marquez, S.; Bjornson, R.; Peltzer, A.; Meng, H.; Aron, E.; Lee, N. Y.; Jensen, C.; Ladd, D.; Hanssen, F.; Heumos, S.; nf-core community, ; Yaari, G.; Kowarik, M. C.; Nahnsen, S.; Kleinstein, S. H.

10.1101/2024.01.18.576147 — bioinformatics — Posted on 2024-01-28

633 Conditional Requirement for Dimerization of the Membrane-Binding Module of BTK

Eisen, T. J.; Ghaffari-Kashani, S.; Groves, J. T.; Weiss, A.; Kuriyan, J.

10.1101/2023.10.05.561114 — biochemistry — Posted on 2024-01-28

634 Discovering Root Causal Genes with High Throughput Perturbations

Strobl, E. V.; Gamazon, E. R.

10.1101/2024.01.13.574491 — genomics — Posted on 2024-01-28

635 Prokrustean graph: An efficient data structure used to extract sequence information for arbitrary k-mer size ranges

Park, A.; Koslicki, D.

10.1101/2023.11.21.568151 — genomics — Posted on 2024-01-28

636 The influence of early moderate prenatal alcohol exposure and maternal diet on offspring DNA methylation: a cross-species study

Bestry, M.; Larcombe, A. N.; Kresoje, N.; Chivers, E. K.; Bakker, C.; Fitzpatrick, J. P.; Elliott, E. J.; Craig, J. M.; Muggli, E.; Halliday, J.; Hutchinson, D.; Buckberry, S.; Lister, R.; Symons, M.; Martino, D.

10.1101/2023.06.15.544516 — genetics — Posted on 2024-01-28

637 Haplotype Function Score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits

Song, W.; Shi, Y.; Lin, G. N.

10.1101/2023.08.08.552392 — genetics — Posted on 2024-01-28

638 Manual gestures facilitate learning lexical stress by modulating auditory neural responses

Zhan, T.; Yang, D.; Wu, R.; Tian, X.

10.1101/2023.11.14.566652 — neuroscience — Posted on 2024-01-28

639 Developmental hourglass: Verification by numerical evolution and elucidation by dynamical-systems theory

Kohsokabe, T.; Kuratani, S.; Kaneko, K.

10.1101/2023.06.05.542718 — systems biology — Posted on 2024-01-28

640 Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner

Shimonty, A.; Pin, F.; Prideaux, M.; Peng, G.; Huot, J.; Kim, H.; Rosen, C. j.; Spiegelman, B. M.; Bonewald, L. F.

10.1101/2023.11.06.565774 — physiology — Posted on 2024-01-28

641 Protein engineering, production, reconstitution in lipid nanoparticles, and initial characterization of the Mycobacterium tuberculosis EfpA drug exporter

Ishola, O.; Ogunbowale, A.; Islam, M. M.; Hadadianpour, E.; Majeed, S.; Adetuyi, O.; Georgieva, E. R.

10.1101/2023.06.26.546575 — biochemistry — Posted on 2024-01-28

642 Four classic de novo genes all have plausible homologs and likely evolved from retro-duplicated or pseudogenic sequences

Hannon, J.

10.1101/2023.05.28.542624 — evolutionary biology — Posted on 2024-01-28

643 Temporal and spatial dynamics within the fungal microbiome of grape fermentation

Onetto, C. A.; Ward, C. M.; Van Den Heuvel, S.; Hale, L.; Cuijvers, K.; Borneman, A.

10.1101/2024.01.15.574562 — microbiology — Posted on 2024-01-28

644 Minimal determinants for lifelong antiviral antibody responses from a single exposure to virus-like immunogens at low doses

Wholey, W.-Y.; Meyer, A. R.; Yoda, S.-T.; Chackerian, B.; Zikherman, J.; Cheng, W.

10.1101/2023.02.20.529089 — immunology — Posted on 2024-01-28

645 Alpha-180 spin-echo based line-scanning method for high resolution laminar-specific fMRI

Choi, S.; Hike, D.; Pohmann, R.; Avdievich, N. I.; Cid, L. G.; Man, W.; Scheffler, K.; Yu, X.

10.1101/2023.05.09.540065 — neuroscience — Posted on 2024-01-28

646 Segregation-to-Integration Transformation (SIT) Model of Memory Evolution

Bavassi, L.; Fuentemilla, L.

10.1101/2023.12.05.570097 — neuroscience — Posted on 2024-01-28

647 Functional characterization of CCHamides and deorphanization of their receptors in the yellow fever mosquito, Aedes aegypti

Tan, J.; Neupert, S.; Paluzzi, J.-P. V.

10.1101/2024.01.27.577569 — zoology — Posted on 2024-01-28

648 C1QA is an invariant biomarker for tissue macrophages

Horowitz, A.; Yu, H.; Pandey, S.; Mishra, B.; Sahoo, D.

10.1101/2024.01.26.577475 — systems biology — Posted on 2024-01-28

649 MoCHI: neural networks to fit interpretable models and quantify energies, energetic couplings, epistasis and allostery from deep mutational scanning data

Faure, A. J.; Lehner, B.

10.1101/2024.01.21.575681 — systems biology — Posted on 2024-01-28

650 PHOSPHATE-INDUCED 1 and its paralogs positively regulate cellulose biosynthesis in Arabidopsis.

Yu, F.; Lu, S.; Jiang, H.; Chen, X.; Yin, S.; Zhuang, Z.; Cao, T.; Wang, X.; Zhang, J.; Liao, Y.; Wang, Q.; Qiu, J.

10.1101/2024.01.24.577082 — plant biology — Posted on 2024-01-28

651 Unveiling the Impact of Vernalization on Seed Oil Content and Fatty Acid Composition in Rapeseed Through Simulated Shorter Winters

Cagli, I.; Kivrak, B. E.; Altunbas, O.; Sonmez, C.

10.1101/2024.01.04.574184 — plant biology — Posted on 2024-01-28

652 A Conserved Mechanism of Cardiac Hypertrophy Regression through FoxO1

Martin, T. G.; Hunt, D. R.; Langer, S. J.; Tan, Y.; Ebmeier, C. C.; Crocini, C.; Chung, E.; Leinwand, L. A.

10.1101/2024.01.27.577585 — physiology — Posted on 2024-01-28

653 Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore module

Schott, K.; Usher, S. G.; Serra, O.; Carnevale, V.; Pless, S.; Chua, H. C.

10.1101/2023.04.12.536537 — pharmacology and toxicology — Posted on 2024-01-28

654 PTBP2 promotes cell survival and autophagy in Chronic Myeloid Leukemia by stabilizing BNIP3

Barik, B.; Lama, S.; IS, S.; Chanda, S.; Biswas, S.; Biswas, G.; Mohapatra, S.; chakraborty, S.

10.1101/2024.01.26.577177 — cancer biology — Posted on 2024-01-28

655 Mechanical stability and unfolding pathways of parallel tetrameric G-quadruplexes probed by pulling simulations

Zhang, Z.; Mlynsky, V.; Krepl, M.; Sponer, J.; Stadlbauer, P.

10.1101/2024.01.26.577375 — biophysics — Posted on 2024-01-28

656 Multi-Channel smFRET study reveals a Compact conformation of EF-G on the Ribosome

Johnson, J.; Steele, J.; Lin, R.; Stepanov, V.; Gavriliuc, M.; wang, y.

10.1101/2024.01.27.577133 — biophysics — Posted on 2024-01-28

657 From Brownian to deterministic motor movement in a DNA-based molecular rotor

Rothfischer, F.; Vogt, M.; Kopperger, E.; Gerland, U.; Simmel, F. C.

10.1101/2024.01.26.577361 — biophysics — Posted on 2024-01-28

658 In Silico Study of the Early Stages of Aggregation of β-Sheet Forming Antimicrobial Peptide GL13K

Niknam Hamidabad, M.; Watson, N. A.; Wright, L. N.; Mansbach, R. A.

10.1101/2024.01.25.577308 — biophysics — Posted on 2024-01-28

659 Trajectory inference from single-cell genomics data with a process time model

Fang, M.; Gorin, G.; Pachter, L.

10.1101/2024.01.26.577510 — bioinformatics — Posted on 2024-01-28

660 Highly specific intracellular ubiquitination of a small molecule

Li, W.; Garcia-Rivera, E. M.; Mitchell, D. C.; Chick, J. M.; Maetani, M.; Knapp, J. M.; Matthews, G. M.; Shirasaki, R.; de Matos Simoes, R.; Viswanathan, V.; Pulice, J. L.; Rees, M. G.; Roth, J. A.; Gygi, S. P.; Mitsiades, C. S.; Kadoch, C.; Schreiber, S. L.; Ostrem, J. M. L.

10.1101/2024.01.26.577493 — biochemistry — Posted on 2024-01-28

661 Visualizing chaperone-mediated multistep assembly of the human 20S proteasome

Adolf, F.; Du, J.; Goodall, E. A.; Walsh, R. M.; rawson, S.; von Gronaua, S.; Harper, J. W.; Hanna, J.; Schulman, B. A.

10.1101/2024.01.27.577538 — biochemistry — Posted on 2024-01-28

662 ACKR3 Proximity Labeling Identifies Novel G protein- and β-arrestin-independent GPCR Interacting Proteins

Hicks, C.; Gardner, J.; Eiger, D. S.; Camarda, N.; Pham, U.; Dhar, S.; Rodriguez, H.; Chundi, A.; Rajagopal, S.

10.1101/2024.01.27.577545 — biochemistry — Posted on 2024-01-28

663 Limited variation in microbial communities across populations of Macrosteles leafhoppers (Hemiptera: Cicadellidae)

Mulio, S. A.; Zwolinska, A.; Klejdysz, T.; Prus-Frankowska, M.; Michalik, A.; Kolasa, M. R.; Lukasik, P.

10.1101/2024.01.28.577611 — evolutionary biology — Posted on 2024-01-28

664 Complex interactions in the life cycle of a simple parasite shape the evolution of virulence

Silva, L. M.; Koella, J. C.

10.1101/2024.01.28.577571 — evolutionary biology — Posted on 2024-01-28

665 Host-associated genetic differentiation in the face of ongoing gene flow: ecological speciation in a pathogenic parasite of freshwater fish

Nazarizadeh, M.; Novakova, M.; Vlcek, J.; Stefka, J.

10.1101/2024.01.27.577373 — evolutionary biology — Posted on 2024-01-28

666 The deubiquitylating enzyme Fat Facets modulates Fat signalling and regulates tissue growth

Dawson, L. E.; Fulford, A. D.; Sekar, A.; Ribeiro, P. S.

10.1101/2024.01.27.577535 — developmental biology — Posted on 2024-01-28

667 Turnover of RNA-binding Proteins and MicroRNAs by intrinsically disordered region-directed ZSWIM8 ubiquitin ligase during brain development

Lei, J.; Zhong, S.; Fan, R.; Shu, X.; Wang, G.; Guo, J.; Xue, S.; Zheng, L.; Ren, A.; Ji, J.; Yang, B.; Duan, S.; Wang, Z.; Guo, X.

10.1101/2024.01.27.577548 — developmental biology — Posted on 2024-01-28

668 Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex

Liebau, J.; Lazzaretti, D.; Bichler, A.; Pilsl, M.; Sprangers, R.

10.1101/2024.01.28.577622 — molecular biology — Posted on 2024-01-28

669 Depot-Specific mRNA Expression Programs in Human Adipocytes Suggest Physiological Specialization via Distinct Developmental Programs

Clemons, H. J.; Hogan, D. J.; Brown, P. O.

10.1101/2024.01.28.577632 — developmental biology — Posted on 2024-01-28

670 Telencephalic eversion in embryos and early larvae of four teleost species

Folgueira, M.; Clarke, J. D. W.

10.1101/2024.01.27.577540 — developmental biology — Posted on 2024-01-28

671 Escherichia coli extra-intestinal population translocation in leukemia patients

Marin, J.; Walewski, V.; Dziri, S.; Magnan, M.; Denamur, E.; Carbonnelle, E.; Bridier-Nahmias, A.

10.1101/2024.01.26.577459 — microbiology — Posted on 2024-01-28

672 Multi-conflict islands are a widespread trend within Serratia spp

Cummins, T.; Garrett, S. R.; Blower, T. R.; Mariano, G.

10.1101/2024.01.28.577318 — microbiology — Posted on 2024-01-28

673 Assembly, stability, and dynamics of the infant gut microbiome are linked to bacterial strains and functions in mother's milk

Allert, M.; Ferretti, P.; Johnson, K.; Heisel, T.; Gonia, S.; Knights, D.; Fields, D. A.; Albert, F. W.; Demerath, E. W.; Gale, C. A.; Blekhman, R.

10.1101/2024.01.28.577594 — microbiology — Posted on 2024-01-28

674 In vivo CRISPR screens identify novel virulence genes among proteins of unassigned subcellular localization in Toxoplasma

Tachibana, Y.; Sasai, M.; Yamamoto, M.

10.1101/2024.01.28.577556 — microbiology — Posted on 2024-01-28

675 Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications

Pozhydaieva, N.; Billau, F. A.; Wolfram-Schauerte, M.; Rojas, A. A. R.; Paczia, N.; Schindler, D.; Höfer, K.

10.1101/2024.01.28.577628 — microbiology — Posted on 2024-01-28

676 KSHV promotes oncogenic FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation

Majerciak, V.; Alvarado-Hernandez, B.; Ma, Y.; Duduskar, S.; Lobanov, A.; Cam, M.; Zheng, Z.-M.

10.1101/2024.01.27.577582 — microbiology — Posted on 2024-01-28

677 Increased regional P2X7R expression detected by GSK1482160 PET in a tauopathy mouse model

Kong, Y.; Cao, L.; Wang, J.; Zhuang, J.; Liu, Y.; Bi, L.; Qiu, Y.; Hou, Y.; Huang, Q.; Xie, F.; Yang, Y.; Shi, K.; Rominger, A.; Guan, Y.; Jin, H.; Ni, R.

10.1101/2024.01.27.575823 — neuroscience — Posted on 2024-01-28

678 Mitotic Activity and DNA Maintenance of Adult Neural Stem Cells is Regulated by Beclin1

Kalinina, A.; Dhaliwal, J.; Xue, Y.; Vaculik, M.; McCambley, M.; Fong, B. C.; Cook, D.; Slack, R. S.; Lagace, D. C.

10.1101/2024.01.26.573092 — neuroscience — Posted on 2024-01-28

679 Re-activation of neurogenic niches in aging brain

Maimon, R.; Chillon-Marinas, C.; Vazquez-Sanchez, S.; Kern, C.; Jenie, K.; Malukhina, K.; Moore, S.; Cui, J.; Gonginashvili, A.; Moghadami, S.; Monell, A.; McAlonis, M.; Jafar-Nejad, P.; Hong, C.; Bennett, C. F.; Ravits, J.; Zhu, Q.; Cleveland, D. W.; Bintu, B.

10.1101/2024.01.27.575940 — neuroscience — Posted on 2024-01-28

680 Distinct Sequential Effects in Space and Time: Repulsion in Direction Judgments and Attraction in Time Reproduction

Cheng, S.; Chen, S.; Shi, Z.

10.1101/2024.01.28.577640 — neuroscience — Posted on 2024-01-28

681 Convolutional neural networks as a model for brain area MSTd

Layton, O.; Steinmetz, S. T.

10.1101/2024.01.26.577393 — neuroscience — Posted on 2024-01-28

682 In vitro survival and neurogenic potential of central canal-derived neural stem cells depend on spinal cord injury type

Schiro, L. E.; Bauer, U. S.; Bjorkli, C.; Sandvig, A.; Sandvig, I.

10.1101/2024.01.27.577563 — neuroscience — Posted on 2024-01-28

683 Brain Vasculature Accumulates Tau and Is Spatially Related to Tau Tangle Pathology in Alzheimer's Disease

Hoglund, Z.; Ruiz-Uribe, N.; del Sastre, E.; Woost, B.; Bailey, J.; Hyman, B.; Bennett, R.; Zwang, T. J.

10.1101/2024.01.27.577088 — neuroscience — Posted on 2024-01-28

684 Efficient enzyme-free isolation of brain-derived extracellular vesicles

Matamoros-Angles, A.; Karadjuzovic, E.; Mohammadi, B.; Song, F.; Brenna, S.; Siebels, B.; Voss, H. L.; Seuring, C.; Ferrer, I.; Schlueter, H.; Kneussel, M.; Altmeppen, H. C.; Schweizer, M.; Puig, B.; Shafiq, M.; Glatzel, M.

10.1101/2024.01.27.577532 — neuroscience — Posted on 2024-01-28

685 Astrocytic tau inclusions lead to microglial abnormalities, but leave neuronal networks intact

Vogels, T.; Vargova, G.; Hromadka, T.

10.1101/2024.01.28.577642 — neuroscience — Posted on 2024-01-28

686 Disruption of autism-associated Pcdh9 gene leads to transcriptional alterations, synapses overgrowth and aberrant excitatory transmission in the CA1

Miozzo, F.; Murru, L.; Maiellano, G.; Zippo, A.; Moretto, E.; Zambrano Avendano, A.; Metodieva, V. D.; Riccardi, S.; D'Aliberti, D.; Spinelli, S.; Canu, T.; Chaabane, L.; Hirano, S.; Kas, M. J. H.; Francolini, M.; Piazza, R.; Passafaro, M.

10.1101/2024.01.27.577576 — neuroscience — Posted on 2024-01-28

687 Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction.

Fournier, L. A.; Phadke, R. A.; Salgado, M.; Brack, A.; Bolshakova, S.; Grant, J. R.; Padro Luna, N. M.; Cruz Martin, A.

10.1101/2024.01.27.575409 — neuroscience — Posted on 2024-01-28

688 Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity

Tutas, J.; Tolve, M.; Oezer Yildiz, E.; Ickert, L.; Klein, I.; Hosseini, M.; Liebsch, F.; Dethloff, F.; Gavalisco, P.; Endepols, H.; Yang, M.; Georgomanolis, T.; Neumaier, B.; Drzezga, A.; Daun, S.; Schwarz, G.; Thorens, B.; Gatto, G.; Frezza, C.; Kononenko, N. L.

10.1101/2024.01.27.577372 — neuroscience — Posted on 2024-01-28

689 Reduced Proactive and Reactive Cognitive Flexibility in Older Adults Underlies Performance Costs During Dual-Task Walking: A Mobile Brain/Body Imaging (MoBI) Study

Richardson, D. R.; Foxe, J. J.; Freedman, E. G.

10.1101/2024.01.27.577090 — neuroscience — Posted on 2024-01-28

690 Planar, Spiral, and Concentric Traveling Waves Distinguish Cognitive States in Human Memory

Das, A.; Zabeh, E.; Ermentrout, B.; Jacobs, J.

10.1101/2024.01.26.577456 — neuroscience — Posted on 2024-01-28

691 Mapping the developmental structure of stereotyped and individual-unique behavioral spaces in C. elegans

Harel, Y.; Nasser, R. A.; Stern, S.

10.1101/2024.01.27.577215 — neuroscience — Posted on 2024-01-28

692 Neural stem cells isolated from activated brain neurogenic niches after traumatic injury demonstrate distinct behaviors in vitro

Schiro, L. E.; Bauer, U. S.; Bjorkli, C.; Sandvig, A.; Sandvig, I.

10.1101/2024.01.27.577567 — neuroscience — Posted on 2024-01-28

693 Cerebrovascular pathology mediates associations between hypoxemia during rapid eye movement sleep and medial temporal lobe structure and function in older adults

Berisha, D. E.; Rizvi, B.; Chappel-Farley, M. G.; Tustison, N.; Taylor, L.; Dave, A.; Sattari, N. S.; Chen, I. Y.; Lui, K. K.; Janecek, J. C.; Keator, D.; Neikrug, A. B.; Benca, R. M.; Yassa, M. A.; Mander, B. A.

10.1101/2024.01.28.577469 — neuroscience — Posted on 2024-01-28

694 Impact of the COVID-19 Pandemic on Undergraduate Research in the Department of Biology at Western University: Effect on project types, learning outcomes, and student perceptions.

Chaplin, A.; Kohalmi, S. E.; Simon, A. F.

10.1101/2024.01.24.577125 — scientific communication and education — Posted on 2024-01-28

695 Solid-state nanopore detection of partially denatured dsDNA with single-strand binding protein: a preliminary analysis

Howald, N.; Klotz, A.

10.1101/2024.01.28.577651 — biophysics — Posted on 2024-01-28

696 Expanding the RNA polymerase biocatalyst solution space for mRNA manufacture

Curry, E.; Sedelnikova, S. E.; Rafferty, J. B.; Hulley, M.; Brown, A.

10.1101/2024.01.28.577649 — bioengineering — Posted on 2024-01-28

697 Self-organizing glycolytic waves fuel cell migration and cancer progression

Zhan, H.; Pal, D. S.; Borleis, J.; Janetopoulos, C.; Huang, C.-H.; Devreotes, P. N.

10.1101/2024.01.28.577603 — biochemistry — Posted on 2024-01-28

698 Degradome analysis to identify direct protein substrates of small-molecule degraders

Jochem, M.; Schrempf, A.; Wagner, L.-M.; Cisneros, J.; Ng, A.; Winter, G. E.; Krijgsveld, J.

10.1101/2024.01.28.577572 — biochemistry — Posted on 2024-01-28

699 Ketone body 3-hydroxybutyrate alleviates CCl4-induced liver fibrosis in mice through anti-inflammatory effects

Zhang, Y.; Liu, X.; Wang, Y.; Liu, M.; Guo, Z.; Zhang, J.; Wu, F.; Chen, G.

10.1101/2024.01.27.577553 — biochemistry — Posted on 2024-01-28

700 LncRNA-CIR6 Mediates Repair of Infarcted Hearts by Inducing MSCs Differentiation into Cardiogenic Cells through CDK1

Cui, X.; Dong, H.; Luo, S.; Zhuang, B.; Li, Y.; Zhong, C.; Ma, Y.; Cheng, X. W.; Hong, L.

10.1101/2024.01.25.577303 — molecular biology — Posted on 2024-01-28

701 Legacy copper/nickel mine tailings potentially harbor novel iron/sulfur cycling microorganisms within highly variable communities

Chen, M.; Gregoire, D. S.; Bain, J. G.; Blowes, D. W.; Hug, L. A.

10.1101/2024.01.24.577127 — microbiology — Posted on 2024-01-28

702 Characterization of antimalarial activity of artemisinin-based hybrid drugs

Moreira, D. R. M.; Quadros, H. C.; Herrmann, L.; Manaranche, J.; Paloque, L.; Borges-Silva, M. C.; Dziwornu, G. A.; D'Alessandro, S.; Chibale, K.; Basilico, N.; Benoit-Vical, F.; Tsogoeva, S.

10.1101/2024.01.26.577447 — microbiology — Posted on 2024-01-28

703 Comprehensive single-cell atlas of the mouse retina

Li, J.; Choi, J.; Cheng, X.; Ma, J.; Pema, S.; Sanes, J.; Mardon, G.; Frankfort, B. J.; Tran, N. M.; Li, Y.; Chen, R. J.

10.1101/2024.01.24.577060 — genomics — Posted on 2024-01-28

704 Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in transwomen

Delgouffe, E.; Silva, S. M.; Chalmel, F.; Cools, W.; Raets, C.; Tilleman, K.; T'Sjoen, G.; Baert, Y.; Goossens, E.

10.1101/2024.01.25.577182 — developmental biology — Posted on 2024-01-28

705 A microRNA that controls the emergence of embryonic movement

Menzies, J. A. C.; Maia Chagas, A.; Alonso, C. R.

10.1101/2024.01.24.577117 — developmental biology — Posted on 2024-01-28

706 Paraoxonase-like APMAP maintains endoplasmic reticulum-associated lipid and lipoprotein homeostasis

Paul, B.; Merta, H.; Ugrankar-Banerjee, R.; Hensley, M.; Tran, S.; Dias do Vale, G.; McDonald, J. G.; Farber, S. A.; Henne, W. M.

10.1101/2024.01.26.577049 — cell biology — Posted on 2024-01-28

707 GRK2-mediated AKT activation controls cell cycle progression and G2-checkpoint in a p53-dependent manner

Rivas, V.; Gonzalez Munoz, T.; Albitre, A.; Lafarga, V.; Mayor, F.; Penela, P.

10.1101/2024.01.26.577358 — molecular biology — Posted on 2024-01-28

708 Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae

Perez, A. J.; Lamanna, M. M.; Bruce, K. E.; Touraev, M. A.; Page, J. E.; Shaw, S. L.; Tsui, H.-C. T.; Winkler, M. E.

10.1101/2024.01.10.575112 — microbiology — Posted on 2024-01-27

709 Phosphate overplus response in Chlamydomonas reinhardtii: polyphosphate dynamics to monitor phosphate uptake and turnover

Zuniga-Burgos, T.; Saiardi, A.; Camargo-Valero, M. A.; Baker, A.

10.1101/2024.01.25.577272 — microbiology — Posted on 2024-01-28

710 Crosstalk between the RNA-binding proteins Regnase-1 and -3 shapes mast cell survival and cytokine expression

Bataclan, M.; Leoni, C.; Moro, S. G.; Pecoraro, M.; Wong, E. H.; Heissmeyer, V.; Monticelli, S.

10.1101/2024.01.24.577016 — immunology — Posted on 2024-01-28

711 Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo

Kempthorne, L.; Vaizoglu, D.; Cammack, A. J.; Carcole, M.; Suklai, P.; Muralidharan, B.; Kroll, F.; Moens, T. G.; Yshii, L.; Verschoren, S.; Holbling, B. V.; Katona, E.; Mikheenko, A.; Coneys, R.; de Oliveira, P.; Zhang, Y.-J.; Jensen, K.; Daughrity, L. M.; McGown, A.; Ramesh, T. M.; Van Den Bosch, L.; Rahim, A. A.; Petrucelli, L.; Rihel, J.; Isaacs, A. M.

10.1101/2024.01.26.577366 — neuroscience — Posted on 2024-01-28

712 Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight

Sakharkar, A.; Lukong, K. E.; Sanders, L. M.; Costes, S. V.; Yang, J.; Taghibiglou, C.

10.1101/2024.01.24.577100 — genomics — Posted on 2024-01-27

713 Target Enrichment Data Uncovers Rapid Radiation, Whole Genome Duplication, and Extensive Hybridization in Slipper Orchid Genus Cypripedium L.

Lagou, L. J.; Kadereit, G.; Morales-Briones, D. F.

10.1101/2024.01.24.577114 — evolutionary biology — Posted on 2024-01-27

714 Time-dependent effects of species interactions at macroevolutionary scale shape the diversity of mimetic butterflies.

Chazot, N.; Pires Braga, M.; Aubier, T. G.; Llaurens, V.; Willmott, K. R.; Elias, M.

10.1101/2024.01.26.577270 — evolutionary biology — Posted on 2024-01-27

715 Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state

Neyhart, E.; Zhou, N.; Munn, B. R.; Law, R. G.; Smith, C.; Mridha, Z. H.; Blanco, F. A.; Li, G.; Li, Y.; McGinley, M. J.; Shine, J. M.; Reimer, J.

10.1101/2023.11.14.567116 — neuroscience — Posted on 2024-01-27

716 Unification of cell-scale metabolic activity with biofilm behavior by integration of advanced flow and reactive-transport modeling and microfluidic experiments

ZHAO, J.; Zarabadi, M.; Hall, D.; Dahal, S.; Greener, J.; Yang, L.

10.1101/2024.01.25.577134 — systems biology — Posted on 2024-01-27

717 Histone acetyltransferase HAF2 associates with PDC to control H3K14ac and H3K23ac in ethylene response

Chen, C.-Y.; Shao, Z.; Wang, G.; Zhao, B.; Hardtke, H. A.; Leong, J.; Zhou, T.; Zhang, Y. J.; Qiao, H.

10.1101/2023.12.31.573642 — plant biology — Posted on 2024-01-27

718 Inducer of CBF Expression 1 (ICE1) Promotes Cold-enhanced Immunity by Directly Activating Salicylic Acid Signaling

Li, S.; Yang, Y.; He, L.; Han, X.; Hu, Y.; Jiang, Y.

10.1101/2023.09.12.557434 — plant biology — Posted on 2024-01-27

719 A multi-institutional study to investigate the sparing effect after whole brain electron FLASH in mice: Reproducibility and temporal evolution of functional, electrophysiological, and neurogenic endpoints

Drayson, O. G. G.; Melemenidis, S.; Katila, N.; Viswanathan, V.; Kramar, E.; Zhang, R.; Kim, R.; Ru, N.; Petit, B.; Dutt, S.; Manjappa, R.; Ashraf, R.; Lau, B. C.; Soto, L.; Skinner, L.; Yu, A.; Surucu, M.; Maxim, P.; Zebadua-Ballasteros, P.; Wood, M.; Baulch, J. E.; Vozenin, M.-C.; Loo, B. W.; Limoli, C.

10.1101/2024.01.25.577164 — cancer biology — Posted on 2024-01-27

720 Rosetta Energy Analysis of AlphaFold2 models: Point Mutations and Conformational Ensembles

Stein, R. A.; Mchaourab, H. S.

10.1101/2023.09.05.556364 — biochemistry — Posted on 2024-01-27

721 Experimental evidence that investment into ejaculation and mating effort impose different life history trade-offs

Chung, M.-H. J.; Fox, R. J.; Jennions, M. D.

10.1101/2024.01.26.577329 — evolutionary biology — Posted on 2024-01-27

722 Transgenic porcine model reveals two distinct LGR5-positive cell populations during lung development and homeostasis

Polkoff, K.; Gupta, N. K.; Murphy, Y.; Lampe, R.; Chung, J.; Carter, A.; Simon, J. M.; Moatti, A.; Kadur Lakshminarasimha Murthy, P.; Gleason, K.; Edwards, L.; Greenbaum, A.; Tata, A.; Tata, P. R.; Piedrahita, J. A.

10.1101/2022.12.09.516617 — cell biology — Posted on 2024-01-27

723 Investigation of Antimicrobial and Antioxidant Activity of Tephromela atra Lichen and its Chemical Isolates, α-Alectoronic Acid and α-Collatolic Acid

Alzebair, A.; YILMAZ CANKILIC, M.; AVAN, I.; CANDAN, M.

10.1101/2023.11.05.565661 — microbiology — Posted on 2024-01-27

724 Cognitive abilities are associated with rapid dynamics of electrophysiological connectome states

Jun, S.; Malone, S. M.; Iacono, W. G.; Harper, J.; Wilson, S.; Sadaghiani, S.

10.1101/2024.01.15.575736 — neuroscience — Posted on 2024-01-27

725 Genetic disruption of dopamine β-hydroxylase dysregulates innate responses to predator odor in mice

Liu, J.; Lustberg, D. J.; Galvez, A.; Liles, L. C.; McCann, K. E.; Weinshenker, D.

10.1101/2023.06.21.545975 — neuroscience — Posted on 2024-01-27

726 Ketamine potentiates a central glutamatergic presynapse

Eshra, A.; Lipstein, N.; Hallermann, S.

10.1101/2023.12.17.571741 — neuroscience — Posted on 2024-01-27

727 Sex-dependent, lateralized engagement of anterior insular cortex inputs to thedorsolateral striatum in binge alcohol drinking

Haggerty, D. L.; Atwood, B.

10.1101/2023.08.23.554484 — neuroscience — Posted on 2024-01-27

728 Coral reef fish resilience and recovery following major environmental disturbances caused by cyclones and coral bleaching: A case study at Lizard Island

Levy, S. A.; Pessina, L.; Bshary, R.; Triki, Z.

10.1101/2024.01.27.577527 — zoology — Posted on 2024-01-27

729 Cell aspect ratio is a mechanical winning strategy in microbial competition

van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.

10.1101/2024.01.26.577059 — biophysics — Posted on 2024-01-27

730 Generalizable features for the diagnosis of infectious disease, autoimmunity and cancer from adaptive immune receptor repertoires

Xu, Z.; Ismanto, H. S.; Saputri, D. S.; Haruna, S.; Sun, G.; Wilamowski, J.; Teraguchi, S.; Sengupta, A.; Standley, D. M.

10.1101/2023.11.28.569125 — bioinformatics — Posted on 2024-01-27

731 k-nonical space: sketching with reverse complements

Marcais, G.; Elder, S.; Kingsford, C.

10.1101/2024.01.25.577301 — bioinformatics — Posted on 2024-01-27

732 The Impact of Anesthesia on Ultrasonic Glymphatic Perturbation Protocol: Alertness, and Glymphatic Influx

Xiao, H.; Shrestha, B.; Cruz, A. A.; Iliff, J.; Porter, T.; Aryal, M.

10.1101/2024.01.24.576888 — bioengineering — Posted on 2024-01-27

733 Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

Ober, V.; Githure, G. B.; Volpato Santos, Y.; Becker, S.; Moya, G.; Basquin, J.; Schwede, F.; Lorentzen, E.; Boshart, M.

10.1101/2023.10.24.563761 — biochemistry — Posted on 2024-01-27

734 10x GENOMICS GENE EXPRESSION FLEX IS A POWERFUL TOOL FOR SINGLE-CELL TRANSCRIPTOMICS OF XENOGRAFT MODELS

10.1101/2024.01.25.577066 — genomics — Posted on 2024-01-27

735 A phylogeny-informed characterisation of global tetrapod traits addresses data gaps and biases

Moura, M. R.; Ceron, K.; Guedes, J. J. M.; Chen-Zhao, R.; Sica, Y. V.; Hart, J.; Dorman, W.; Portmann, J. M.; Gonzalez del Pliego, P.; Ranipeta, A.; Catenazzi, A.; Werneck, F.; Toledo, L. F.; Upham, N. S.; Tonini, J. F. R.; Colston, T. J.; Guralnick, R. P.; Bowie, R. C. K.; Pyron, R. A.; Jetz, W.

10.1101/2023.03.04.531098 — ecology — Posted on 2024-01-27

736 DNA metabarcoding-based detection of non-indigenous invertebrates in recreational marinas: influence of sample type and seasonal variation

Lavrador, A. S.; Amaral, F. G.; Moutinho, J.; Vieira, P. E.; Costa, F. O.; Duarte, S.

10.1101/2024.01.25.577180 — ecology — Posted on 2024-01-27

737 A fungi hotspot deep down the ocean: explaining the presence of Gjaerumia minor in Equatorial Pacific bathypelagic waters

Pernice, M. C.; Forn, I.; Logares, R.; Massana, R.

10.1101/2024.01.25.577184 — ecology — Posted on 2024-01-27

738 Analyzing the implications of protein folding delay caused by translation

Houben, B.; Duran-Romana, R.; Fernandez Migens, P.; Rousseau, F.; Schymkowitz, J.

10.1101/2024.01.27.577370 — molecular biology — Posted on 2024-01-27

739 Growing a cystic fibrosis-relevant polymicrobial biofilm to probe community phenotypes.

Poirier, S.; Jean-Pierre, F.

10.1101/2024.01.26.577445 — microbiology — Posted on 2024-01-27

740 Acid-treated Staphylococcus aureus induces acute silkworm hemolymph melanization

Matsumoto, Y.; Sato, E.; Sugita, T.

10.1101/2024.01.26.577519 — microbiology — Posted on 2024-01-27

741 Thermal fluctuations independently modulate physiological plasticity and the dynamics of the gut microbiome in a tropical rocky shore oyster

Arromrak, B. S.; Wong, A. T. C.; Hui, T. Y.; Leung, K. S.; Williams, G. A.; Ganmanee, M.; Durand, T.; Lee, J. C. Y.; Gaitan-Espitia, J. D.

10.1101/2023.02.08.527599 — microbiology — Posted on 2024-01-27

742 Copy number flexibility facilitates heteroresistance to increasing antibiotic pressure and threatens the beta-lactam pipeline

Choby, J. E.; Ozturk, T.; Abbott, C. N.; Nnabuife, C.; Colquhoun, J. M.; Satola, S. W.; Rather, P. N.; Palzkill, T.; Weiss, D. S.

10.1101/2022.06.07.494873 — microbiology — Posted on 2024-01-27

743 IgG hexamers initiate acute lung injury

Cleary, S. J.; Seo, Y.; Tian, J. J.; Kwaan, N.; Bulkley, D. P.; Bentlage, A. E.; Vidarsson, G.; Boilard, E.; Spirig, R.; Zimring, J. C.; Looney, M. R.

10.1101/2024.01.24.577129 — immunology — Posted on 2024-01-27

744 Rapid dynamics of electrophysiological connectome states are heritable

Jun, S.; Malone, S.; Iacono, W. G.; Harper, J.; Wilson, S.; Sadaghiani, S.

10.1101/2024.01.15.575731 — neuroscience — Posted on 2024-01-27

745 Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Sakenova, N.; Cacace, E.; Orakov, A.; Huber, F.; Varik, V.; Kritikos, G.; Michiels, J.; Bork, P.; Cossart, P.; Goemans, C.; Typas, A.

10.1101/2024.01.25.576750 — systems biology — Posted on 2024-01-27

746 Assessing the Adequacy of Morphological Models used in Palaeobiology

Mulvey, L. P. A.; May, M. R.; Brown, J. M.; Hoehna, S.; Wright, A. M.; Warnock, R. C. M.

10.1101/2024.01.25.577179 — paleontology — Posted on 2024-01-27

747 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays

Van Vranken, J. G.; Li, J.; Mintseris, J.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D.

10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-01-27

748 Centromere landscapes resolved from hundreds of human genomes

Gao, S.; Zhang, Y.; Bush, S. J.; Wang, B.; Yang, X.; Ye, K.

10.1101/2024.01.26.577337 — genomics — Posted on 2024-01-27

749 A critical role for Pol II CTD phosphorylation in heterochromatic gene activation

Kainth, A. S.; Zhang, H.; Gross, D. S.

10.1101/2024.01.26.577526 — genetics — Posted on 2024-01-27

750 Patient derived model of UBA5-associated encephalopathy identifies defects in neurodevelopment and highlights potential therapies

Chen, H.; Wang, Y.-D.; Blan, A. W.; Almanza-Fuerte, E. P.; Bonkowski, E. S.; Bajpai, R.; Pruett-Miller, S. M.; Mefford, H. C.

10.1101/2024.01.25.577254 — genetics — Posted on 2024-01-27

751 Scarcity of fixed carbon transfer in a model microbial phototroph-heterotroph interaction

Dupuis, S.; Lingappa, U. F.; Mayali, X.; Sindermann, E. S.; Chastain, J. L.; Weber, P. K.; Stuart, R.; Merchant, S. S.

10.1101/2024.01.26.577492 — microbiology — Posted on 2024-01-27

752 Regulatory T cells control type 1-driven immunopathology restraining GM-CSF-producing helper T cells

Costa-Pereira, S.; Lanzinger, M.; Andreadou, M.; Nunez, N.; Villar-Vesga, J.; Prisco, F.; Hane, P.; Roussel, E.; Krishnarajah, S.; Lindemann, R. C.; Westermann, F.; Oberbichler, L.; Sethi, A.; Fonseca, A.; Pinzger, M.; Tugues, S.; Mundt, S.; Kipar, A.; Greter, M.; De Feo, D.; Becher, B.

10.1101/2024.01.24.577048 — immunology — Posted on 2024-01-27

753 Mitochondrial Transplantation promotes protective effector and memory CD4+ T cell response during Mycobacterium tuberculosis infection and diminishes exhaustion and senescence in elderly CD4+ T cells

Headley, C. A.; Guatam, s.; Olmo-Fontanez, A. M.; Garcia-Vilanova, A.; Dwivedi, V.; Schami, A. A.; Weintraub, S.; Tsao, P. S.; Torrelles, J. B.; Turner, J.

10.1101/2024.01.24.577036 — immunology — Posted on 2024-01-27

754 Cell morphology as a quantifier for functional states of resident tissue macrophages

Schnitzerlein, M.; Wegner, A.; Ben Brahim, O.; Uderhardt, S.; Zaburdaev, V.

10.1101/2024.01.24.577158 — immunology — Posted on 2024-01-27

755 An Evaluation of the Tumor Microenvironment through CALR, IL1R1, IFNB1, and IFNG to Assess Prognosis and Immunotherapy Response in Bladder Cancer Patients

Lilong, L.; Zhenghao, L.; Lei, F.; Zhipeng, Y.; Junyi, H.; Yaxin, H.; Yang, L.; Yuhong, D.; Yingchun, K.; Ke, C.; Yi, H.; Zheng, L.

10.1101/2024.01.24.577030 — immunology — Posted on 2024-01-27

756 Predicting microbial genome-scale metabolic networks directly from 16S rRNA gene sequences

Oyas, O.; Kobel, C. M.; Vik, J. O.; Pope, P. B.

10.1101/2024.01.26.576649 — systems biology — Posted on 2024-01-27

757 Genome-wide analysis of the class III peroxidase gene family in Physcomitrium patens and a search for clues to ancient class III peroxidase functions

Aparato, V. P.; Rabbi, F.; Madarash, T.; Brisbourne, W. A.; Barker, E. I.; Suh, D.-Y.

10.1101/2024.01.25.577222 — plant biology — Posted on 2024-01-27

758 The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo

Echterhof, A.; Dharmaraj, T.; McBride, R.; Berry, J. D.; Hopkins, M.; Selvakumar, H.; Lin, K.-Y.; Chia, L.; Shen, C.-C.; Lioa, W.; Lee, P.; Yeh, T.; Suh, G.; Blankenberg, F. G.; Frymoyer, A.; Bollyky, P.

10.1101/2024.01.25.577154 — pharmacology and toxicology — Posted on 2024-01-27

759 Computation-aided Design of Rod-Shaped Janus Base Nanopieces for Improved Tissue Penetration and Therapeutics Delivery

Lee, J.; Zhang, W.; Nguyen, D.; Zhou, L.; Amengual, J.; Zhai, J.; Cote, T.; Landolina, M.; Ahmadi, E.; Mishra, N.; Yu, H.; Nieh, M.-P.; Wang, K.; Li, Y.; Chen, Y.

10.1101/2024.01.24.577046 — bioengineering — Posted on 2024-01-27

760 Human vascular organoids with a mosaic AKT1 mutation recapitulate Proteus syndrome

He, S.; Zhu, Y.; Chauhan, S.; Tavakol, D. N.; Lee, J. H.; Berris, R. B.-L.; Xu, C.; Lee, J.; Lee, C.; Cai, S.; McElroy, S.; Vunjak-Novakovic, G.; Tomer, R.; Azizi, E.; Xu, B.; Lao, Y.-H.; Leong, K. W.

10.1101/2024.01.26.577324 — bioengineering — Posted on 2024-01-27

761 In silico {lambda}-dynamics predicts protein binding specificities to modified RNAs

Angelo, M.; Zhang, W.; Vilseck, J. Z.; Aoki, S. T.

10.1101/2024.01.26.577511 — biochemistry — Posted on 2024-01-27

762 Structure of the extracellular region of the adhesion GPCR CELSR1 reveals a compact module which regulates G protein-coupling

Bandekar, S. J.; Garbett, K.; Kordon, S. P.; Dintzner, E.; Shearer, T.; Sando, R.; Arac, D.

10.1101/2024.01.26.577439 — biochemistry — Posted on 2024-01-27

763 Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition

Azadmanesh, J.; Slobodnik, K.; Struble, L.; Lutz, W. E.; Coates, L.; Weiss, K. L.; Myles, D. A. A.; Kroll, T.; Borgstahl, G. E.

10.1101/2024.01.26.577433 — biochemistry — Posted on 2024-01-27

764 Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding

Jing, T.; Shan, Z.; Dinh, T.; Biswas, A.; Jang, S.; Greenwood, J.; Li, M.; Zhang, Z.; Gray, G.; Shin, H. J.; Zhou, B.; Passos, D.; Aiyer, S.; Li, Z.; Craigie, R.; Engelman, A. N.; Kvaratskhelia, M.; Lyumkis, D.

10.1101/2024.01.26.577436 — biochemistry — Posted on 2024-01-27

765 Environmental and Population influences on Mummichog (Fundulus heteroclitus) Gut Microbiomes

Ma, L.; Hahn, M. E.; Karchner, S. I.; Nacci, D.; Clark, B. W.; Apprill, A.

10.1101/2024.01.26.577513 — ecology — Posted on 2024-01-27

766 Impaired glycolysis in aged endothelial cells is associated with reduced neovascularisation upon tissue ischemia

Kiesworo, K.; Agius, T.; Lyon, A.; Macarthur, M. R.; Zhang, J.; Deglise, S.; Markmann, J. F.; Uygun, K.; Yeh, H.; De Bock, K.; Mitchell, S. J.; Ocampo, A.; Allagnat, F.; Longchamp, A.

10.1101/2024.01.26.577495 — molecular biology — Posted on 2024-01-27

767 Production of OSU G5P Porcine Rotavirus Expressing a Fluorescent Reporter by Reverse Genetics

Snyder, A. J.; Agbemabiese, C. A.; Patton, J. T.

10.1101/2024.01.26.577454 — microbiology — Posted on 2024-01-27

768 Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of Drosophila larvae

Tleiss, F.; Montanari, M.; Pierre, O.; Royet, J.; Osman, D.; Gallet, A.; Kurz, C. L.

10.1101/2024.01.26.577406 — immunology — Posted on 2024-01-27

769 An accessible digital imaging workflow for multiplexed quantitative analysis of adult eye phenotypes in Drosophila melanogaster

Pipkin, H. J. J.; Lindsay, H. L.; Smiley, A. T.; Jurmu, J. D.; Arsham, A. M.

10.1101/2024.01.26.577286 — genetics — Posted on 2024-01-27

770 Cannabis sativa (Hemp) seed-derived peptides WVYY and PSLPA modulate the Nrf2 signaling pathway in human keratinocytes

Kim, E.; Jang, j.; Seo, H. H.; Lee, J. H.; Moh, S. H.

10.1101/2024.01.26.577509 — cell biology — Posted on 2024-01-27

771 Motor neurons are dispensable for the assembly of a sensorimotor circuit for gaze stabilization

Goldblatt, D.; Rosti, B.; Hamling, K. R.; Leary, P.; Panchal, H.; Li, M.; Huang, S.; Quainoo, C.; Schoppik, D.

10.1101/2024.01.25.577261 — neuroscience — Posted on 2024-01-27

772 PI3Kγ promotes neutrophil extracellular trap formation by noncanonical pyroptosis in abdominal aortic aneurysm

Xiong, Y.; Liu, S.; Liu, Y.; Zhao, J.; Sun, J.; Pan, B.; Wang, W.

10.1101/2024.01.26.577503 — cell biology — Posted on 2024-01-27

773 Increased interaction between connexin43 and microtubules is critical for glioblastoma stem-like cell maintenance and tumorigenicity.

Smyth, J. W.; Guo, S.; O'Rourke, L.; Deaver, S.; Dahlka, J.; Nurmemmedov, E.; Sheng, Z.; Gourdie, R. G.; Lamouille, S.

10.1101/2024.01.26.576347 — cancer biology — Posted on 2024-01-27

774 FBM: Freestanding bilayer microscope for single-molecule imaging of membrane proteins

Perez-Mitta, G.; Sezgin, Y.; Wang, W.; MacKinnon, R.

10.1101/2024.01.26.577465 — biophysics — Posted on 2024-01-27

775 Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits

Hao, Y.; Yan, J.; Fraser, C.; Jiang, A.; Anuganti, M.; Zhang, R.; Lloyd, K.; Jardine, J.; Coppola, J.; Meijers, R.; Li, J.; Springer, T. A.

10.1101/2024.01.26.577394 — cell biology — Posted on 2024-01-27

776 mTORC3 activity is regulated by GSK3β through the activation of PKCδ that phosphorylates and activates STAT1.

Zhan, J.; Harwood, F. C.; Cardone, M.; Grosveld, G. C.

10.1101/2024.01.26.577410 — cell biology — Posted on 2024-01-27

777 Pregnancy-associated oxidative stress and inflammation are not associated with impaired maternal neuronal activity or memory function

Bradshaw, J. L.; Wilson, E. N.; Gardner, J. J.; Mabry, S.; Tucker, S. M.; Rybalchenko, N.; Vera, E.; Goulopoulou, S.; Cunningham, R. L.

10.1101/2024.01.26.577461 — animal behavior and cognition — Posted on 2024-01-27

778 A new genetically tractable non-vertebrate system to study complete camera-type eye regeneration

Accorsi, A.; Pardo, B.; Ross, E.; Corbin, T. J.; McClain, M.; Weaver, K.; Delventhal, K.; Morrison, J. A.; McKinney, M. C.; McKinney, S. A.; Sanchez Alvarado, A.

10.1101/2024.01.26.577494 — developmental biology — Posted on 2024-01-27

779 From Nutritional Patterns to Behavior: High-Fat Diet Influences on Inhibitory Control, Brain Gene Expression and Metabolomics in Rats

Ruiz-Sobremazas, D.; Abreu, A. C.; Prados Pardo, A.; Martin-Gonzalez, E.; Isabel Tristan, A.; Fernandez, I.; Moreno, M.; Mora, S.

10.1101/2024.01.26.577449 — neuroscience — Posted on 2024-01-27

780 Zebrafish live imaging reveals only around 2% rather than 50% of motor neurons die through apoptosis during development

Jia, H.; Yang, H.; Luo, K.

10.1101/2024.01.26.577434 — neuroscience — Posted on 2024-01-27

781 LOCAL SPATIAL FLOWS AND PROPAGATIVE ATTRACTORS: A NOVEL 'FLOWNECTOME' FRAMEWORK FOR ANALYZING BOLD FMRI DYNAMICS

Miller, R.; Vergara, V. M.; Erhardt, E.; Calhoun, V.

10.1101/2024.01.26.576775 — neuroscience — Posted on 2024-01-27

782 Hyper-Flexible Neural Networks: Rapidly Switching between Logic Operations in a Compact 4-Neuron Circuit

White, A. J.; Liu, B.; Hsieh, M.-J.; Wu, K.-a.; Lo, C.-C.

10.1101/2024.01.26.574759 — neuroscience — Posted on 2024-01-27

783 Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation with Nicotine Contents and Effects on Product Preference

Jabba, S. V.; Silinski, P.; Yang, A. Y.; Ouyang, W.; Jordt, S. E.

10.1101/2024.01.26.577472 — animal behavior and cognition — Posted on 2024-01-27

784 Early dynamics of excitation and inhibition maintain late frequency tuning in auditory cortex

Reid, A. P.; Hromadka, T.; Zador, A. M.

10.1101/2024.01.26.577483 — neuroscience — Posted on 2024-01-27

785 Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53

Godthi, A.; Min, S.; Srijit, D.; Cruz-Corchado, J.; Deonarine, A.; Misel-Wuchter, K.; Issuree, P. D.; Prahlad, V.

10.1101/2022.11.22.517560 — developmental biology — Posted on 2024-01-27

786 Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by maintenance of cAMP level

Khan, H.; Paul, P.; Goar, H.; Bamniya, B.; Baid, N.; Sarkar, D.

10.1101/2022.03.07.483216 — microbiology — Posted on 2024-01-27

787 Cell Type Specific Responses of the Endoplasmic Reticulum Dynamics to Environmental Stress

Zhang, Y.; Liu, J.; Sun, Z.; Guo, J.; Yuan, J.; Xue, Y.; Qiu, T.; Wang, P.; Yin, B.; Yang, H.; Zhai, L.; Han, H.; Li, X.

10.1101/2024.01.23.576814 — plant biology — Posted on 2024-01-27

788 Developmental tinkering of gene regulation facilitated super rapid adaptive radiation

Duenser, A.; Singh, P.; Ahi, E. P.; Durdevic, M.; Schaeffer, S.; Gessl, W.; Seehausen, O.; Sturmbauer, C.

10.1101/2024.01.24.577063 — evolutionary biology — Posted on 2024-01-27

789 Fruitless mating with the exes: the irreversible parthenogenesis in a stick insect

Nozaki, T.; Chikami, Y.; Yano, K.; Sato, R.; Suetsugu, K.; Kaneko, S.

10.1101/2023.07.28.550994 — evolutionary biology — Posted on 2024-01-27

790 The Neural Basis of Event Segmentation:Stable Features in the Environment areReflected by Neural States

Oetringer, D.; Gözükara, D.; Güclü, U.; Geerligs, L.

10.1101/2024.01.26.577369 — neuroscience — Posted on 2024-01-27

791 Metabotropic NMDA Receptor Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory

Le, A. A.; Lauterborn, J. C.; Cox, C. D.; Jia, Y.; Lynch, G.; Gall, C. M.

10.1101/2024.01.26.577478 — neuroscience — Posted on 2024-01-27

792 Inferring neural dynamics of memory during naturalistic social communication

Pang, R.; Baker, C. A.; Murthy, M.; Pillow, J. W.

10.1101/2024.01.26.577404 — neuroscience — Posted on 2024-01-27

793 Dissociation of attentional state and behavioral outcome using local field potentials

Prakash, S. S.; Mayo, J. P.; Ray, S.

10.1101/2023.08.05.552102 — neuroscience — Posted on 2024-01-27

794 Comparative Brain-Wide Mapping of Ketamine and Isoflurane-Activated Nuclei and Functional Networks

Hu, Y.; Du, W.; Qi, J.; Luo, H.; Zhang, Z.; Luo, M.; Wang, Y.

10.1101/2023.06.03.543576 — neuroscience — Posted on 2024-01-27

795 Solving the time-dependent protein distributions for autoregulated bursty gene expression using spectral decomposition

Wu, B.; James, H.; Grima, R.; Jia, C.

10.1101/2023.11.21.568174 — systems biology — Posted on 2024-01-27

796 A rule-based multiscale model of hepatic stellate cell plasticity: critical role of the inactivation loop in fibrosis progression

Bougueon, M.; Legagneux, V.; Hazard, O.; Bomo, J.; Siegel, A.; Feret, J.; Theret, N.

10.1101/2024.01.24.577157 — systems biology — Posted on 2024-01-26

797 Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts

Lachat, J.; Lextrait, G.; Jouan, R.; Boukherissa, A.; Yokota, A.; Jang, S.; Ishigami, K.; Futahashi, R.; Cossard, R.; Naquin, D.; Costache, V.; Augusto, L.; Tissiere, P.; Biondi, E. G.; Alunni, B.; Timchenko, T.; Ohbayashi, T.; Kikuchi, Y.; Mergaert, P.

10.1101/2023.10.16.562546 — microbiology — Posted on 2024-01-26

798 Human-aided dispersal facilitates parasitism escape in the most invasive mosquito species

GIRARD, M.; Luis, P.; HAY DE BETTIGNIES, A. E.; Moro, C. V.; Minard, G.

10.1101/2023.02.20.529246 — microbiology — Posted on 2024-01-26

799 Delivery of loaded MR1 Monomer Results in Efficient Ligand Exchange to Host MR1 and Subsequent MR1T cell activation

Kulicke, C. A.; Swarbrick, G. M.; Ladd, N. A.; Cansler, M.; Null, M.; Worley, A.; Lemon, C.; Ahmed, T.; Bennett, J.; Lust, T. N.; Heisler, C. M.; Huber, M. E.; Krawic, J. R.; Ankley, L. M.; McBride, S. K.; Tafesse, F. G.; Olive, A.; Hildebrand, W. H.; Lewinsohn, D. A.; Adams, E. J.; Lewinsohn, D. M.; Harriff, M. J.

10.1101/2022.07.11.499573 — immunology — Posted on 2024-01-26

800 Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy

Keshari, S.; Shavkunov, A. S.; Miao, Q.; Saha, A.; Williams, C. D.; Highsmith, A. M.; Pineda, J. E.; Alspach, E.; Hu, K.; Pauken, K. E.; Chen, K.; Gubin, M. M.

10.1101/2023.12.20.570816 — immunology — Posted on 2024-01-26

801 Spatial neglect after stroke is reduced when lying inside a 3T MRI scanner

Karnath, H.-O.; Rosenzopf, H.; Stammler, B.; Smaczny, S.; Lindner, A.

10.1101/2022.08.01.502290 — neuroscience — Posted on 2024-01-26

802 Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

Cheong, H. S. J.; Eichler, K.; Stuerner, T.; Asinof, S. K.; Champion, A. S.; Marin, E. C.; Oram, T. B.; Sumathipala, M.; Venkatasubramanian, L.; Namiki, S.; Siwanowicz, I.; Costa, M.; Berg, S.; Janelia FlyEM Project Team, ; Jefferis, G. S. X. E.; Card, G. M.

10.1101/2023.06.07.543976 — neuroscience — Posted on 2024-01-26

803 Inhibitory tagging both speeds and strengthens saccade target selection in the superior colliculus during visual search

Conroy, C.; Nanjappa, R.; McPeek, R. M.

10.1101/2023.09.20.558470 — neuroscience — Posted on 2024-01-26

804 Axon arrival times and physical occupancy establish visual projection neuron integration on developing dendrites in the Drosophila optic glomeruli.

McFarland, B. W.; Jang, H.; Smolin, N.; Hina, B. W.; Parisi, M. J.; Davis, K. C.; Mosca, T. J.; Godenschwege, T. A.; Nern, A.; Kurmangaliyev, Y. Z.; von Reyn, C. R.

10.1101/2022.08.20.504653 — neuroscience — Posted on 2024-01-26

805 Mechanically induced localization of SECONDARY WALL INTERACTING bZIP is associated with thigmomorphogenic and secondary cell wall gene expression

Coomey, J. H.; MacKinnon, K. J.-M.; McCahill, I. W.; Khahani, B.; Handakumbura, P.; Trabucco, G. M.; Mazzola, J.; Leblanc, N. A.; Kheam, R.; Hernandez-Romero, M.; Barry, K. W.; Liu, L.; Lee, J. E.; Vogel, J. P.; O'Malley, R.; Chambers, J. J.; Hazen, S. P.

10.1101/2021.02.03.429573 — plant biology — Posted on 2024-01-26

806 Multiple distinct evolutionary mechanisms govern the dynamics of selfish mitochondrial genomes

Gitschlag, B. L.; Pereira, C. V.; Held, J. P.; McCandlish, D. M.; Patel, M. R.

10.1101/2022.04.08.487647 — evolutionary biology — Posted on 2024-01-26

807 Upscaling biodiversity monitoring: Metabarcoding estimates 31,846 insect species from Malaise traps across Germany

Buchner, D.; Sinclair, J.; Ayasse, M.; Beermann, A. J.; Buse, J.; Dziock, F.; Enss, J.; Frenzel, M.; Hoerren, T. P. B.; Li, Y.; Monaghan, M. T.; Morkel, C.; Mueller, J.; Pauls, S. U.; Richter, R.; Scharnweber, T.; Sorg, M.; Stoll, S.; Twietmeyer, S.; Weisser, W.; Wiggering, B.; Wilmking, M.; Zotz, G.; Gessner, M. O.; Haase, P.; Leese, F.

10.1101/2023.05.04.539402 — ecology — Posted on 2024-01-26

808 Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress

Dar, S. A.; Malla, S.; Martinek, V.; Payea, M. J.; Lee, C. T.-Y.; Martin, J.; Khandeshi, A. J.; Martindale, J. L.; Belair, C.; Maragkakis, M.

10.1101/2023.08.31.555629 — cell biology — Posted on 2024-01-26

809 Mechanosensing through talin 1 contributes to tissue mechanical homeostasis

Chanduri, M. V.; Kumar, A.; Weiss, D.; Emuna, N.; Barsukov, I.; Shi, M.; Tanaka, K.; Wang, X.; Datye, A.; Kanyo, J.; Collin, F.; Lam, T.; Schwarz, U. D.; Bai, S.; Nottoli, T.; Goult, B. T.; Humphrey, J. T.; Schwartz, M. A.

10.1101/2023.09.03.556084 — cell biology — Posted on 2024-01-26

810 Optogenetic activation of dorsal raphe serotonin neurons induces brain-wide activation

Hamada, H. T.; Abe, Y.; Takata, N.; Taira, M.; Tanaka, K. F.; Doya, K.

10.1101/2022.08.07.503074 — neuroscience — Posted on 2024-01-26

811 NeuroFreq: a MATLAB Toolbox for Time-Frequency Analysis of M/EEG Data

Rawls, E.

10.1101/2023.11.01.565154 — neuroscience — Posted on 2024-01-26

812 Estrogens dynamically regulate neurogenesis in the dentate gyrus of adult female rats

Yagi, S.; Wen, Y.; Batallan Burrowes, A.; Blankers, S.; Galea, L.

10.1101/2022.09.30.510371 — neuroscience — Posted on 2024-01-26

813 The mouse dorsal peduncular cortex encodes fear memory

Campos-Cardoso, R.; Desa, Z.; Fitzgerald, B.; Moore, A.; Duhon, J.; Landar, V.; Clem, R.; Cummings, K. A.

10.1101/2023.07.24.550408 — neuroscience — Posted on 2024-01-26

814 Geometry of anisotropic contextual interactions in the visual cortex places fundamental limits on spatial vision

Morton, M. P.; Denagamage, S.; Hudson, N. V.; Nandy, A. S.

10.1101/2023.08.15.553380 — neuroscience — Posted on 2024-01-26

815 m6A-dependent circular RNA formation mediatestau-induced neurotoxicity

Atrian, F.; Ramirez, P.; De Mange, J.; Marquez, M.; Gonzalez, E. M.; Minaya, M.; Karch, C.; Frost, B.

10.1101/2024.01.25.577211 — neuroscience — Posted on 2024-01-26

816 Investigating the neural basis of schematic false memories by examining schematic and lure pattern similarity

Carpenter, C. M.; Dennis, N. A.

10.1101/2023.07.26.550683 — neuroscience — Posted on 2024-01-26

817 XKidneyOnco: An Explainable Framework to Classify Renal Oncocytoma and Chromophobe Renal Cell Carcinoma with a Small Sample Size

Javaheri, T.; Heidari, S.; Yang, X.; Yerra, S.; Seidi, K.; Setayesh, T.; Zhang, G.; Chitkushev, L.; Salar, S. S.; Sayeeduddin, Z.; Zarrin-Khameh, N.; Gharib, M. H.; Castro, P.; Haeri, M.; Rawassizadeh, R.

10.1101/2024.01.23.576782 — pathology — Posted on 2024-01-26

818 Transgenic αβ TCR tonic signaling is leukemogenic while strong stimulation is leukemia-suppressive

Catarino, T. A.; Pacheco-Leyva, I.; Pereira, J. L.; Baessa, M.; dos Santos, N. R.

10.1101/2024.01.17.576006 — cancer biology — Posted on 2024-01-26

819 Deciphering the phenotypic heterogeneity and drug response in cancer cells using genome-wide activity and interaction of chromatin domains.

Pandey, N.; Sharma, M.; Mathur, A.; Nzelu, G. A.; Hakimullah, M.; Jha, I. P.; Chandra, O.; Mishra, S.; Bhattacharya, J.; Sharma, A.; Foo, R.; Sandhu, K. S.; Mandoli, A.; DasGupta, R.; KUMAR, V.

10.1101/2023.01.15.524115 — cancer biology — Posted on 2024-01-26

820 Genomic features of NF1-associated peripheral nerve sheath tumors: a cohort analysis from the Johns Hopkins NF1 biospecimen repository

Banerjee, J.; Lyu, Y.; Makri, S. C.; Scott, A. J.; Zhang, L.; Calizo, A.; Pollard, K.; Yang, K.; Gross, J. M.; Wang, J.; Romo, C. G.; Allaway, R. J.; Blakeley, J. O.; Hirbe, A. C.; Pratilas, C. A.

10.1101/2024.01.23.576977 — bioinformatics — Posted on 2024-01-26

821 A Dynamic Programming Approach for the Alignment of Molecules

Williams, R. A.; Liberles, D.

10.1101/2024.01.23.576849 — bioinformatics — Posted on 2024-01-26

822 MiRGraph: A transformer-based feature learning approach to identify miRNA-target interactions

Liu, P.; Liu, Y.; Luo, J.; Li, Y.

10.1101/2023.11.04.565620 — bioinformatics — Posted on 2024-01-26

823 Accurate quantification of single-cell and single-nucleus RNA-seq transcripts using distinguishing flanking k-mers

Eldjarn Hjörleifsson, K.; Sullivan, D. K.; Swarna, N. P.; Holley, G.; Melsted, P.; Pachter, L.

10.1101/2022.12.02.518832 — bioinformatics — Posted on 2024-01-26

824 Ratiometric pH Imaging of Macrophage Lysosomes Using the Novel pH-sensitive Dye ApHID.

Sole-Domenech, S.; Kumar Singh, P.; Warren, J. D.; Maxfield, F. R.

10.1101/2024.01.20.576118 — biochemistry — Posted on 2024-01-26

825 A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.

Tesson, F.; Planel, R.; Egorov, A. A.; Georjon, H.; Vaysset, H.; Brancotte, B.; Neron, B.; Mordret, E.; Atkinson, G. C.; Bernheim, A.; Cury, J.

10.1101/2024.01.25.577194 — genomics — Posted on 2024-01-26

826 DIB-BOT: An open-source hardware approach for high throughput droplet interface bilayer deposition

Mason, A. F.; Wickham, S. F.; Baker, M. A.

10.1101/2024.01.26.577347 — synthetic biology — Posted on 2024-01-26

827 Analysis of Methicillin Resistance in Staphylococcus Aureus Sepsis Using TDbasedUFE

Watanabe, S.; Taguchi, Y.-h.

10.1101/2024.01.25.577291 — bioinformatics — Posted on 2024-01-26

828 Evolution, diversity, function, and marker-based elimination of the disease susceptibility gene Snn1 in wheat

Seneviratne, S.; Shi, G.; Szabo-Hever, A.; Zhang, Z.; Peters Haugrud, A.; Running, K. L. D.; Singh, G.; Nandety, R. S.; Fiedler, J. D.; McClean, P. E.; Xu, S.; Friesen, T. L.; Faris, J. D.

10.1101/2024.01.24.577084 — genetics — Posted on 2024-01-26

829 Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1

Brasino, M.; Wagnell, E.; Ozdemir, S.; Ranganathan, S.; Merritt, J.

10.1101/2024.01.25.577207 — synthetic biology — Posted on 2024-01-26

830 An experimental census of retrons for DNA production and genome editing

Khan, A. G.; Rojas-Montero, M.; Gonzalez-Delgado, A.; Lopez, S. C.; Fang, R. F.; Shipman, S. L.

10.1101/2024.01.25.577267 — bioengineering — Posted on 2024-01-26

831 Multifaceted Roles of Histone Lysine Lactylation in Meiotic Gene Dynamics and Recombination

Zhang, X.; Liu, Y.; Wang, N.

10.1101/2024.01.25.576681 — genetics — Posted on 2024-01-26

832 An end-to-end workflow to study newly synthesized mRNA following rapid protein depletion in Saccharomyces cerevisiae

Ridenour, J. B.; Donczew, R.

10.1101/2024.01.26.577353 — molecular biology — Posted on 2024-01-26

833 Induction of NASH and vacuolar structures in the Nwd1-/- mouse liver via SERCA2-dependent endoplasmic reticulum stress

Yamada, S.; Nakadate, K.; Mizukoshi, T.; Kawakami, K.; Kobayashi, R.; Horii, T.; Hatada, I.; Sakakibara, S.-i.

10.1101/2024.01.26.577307 — molecular biology — Posted on 2024-01-26

834 Engineered minimal type I CRISPR-Cas system for transcriptional activation and base editing in human cells

Guo, J.; Gong, L.; Yu, H.; Li, M.; Liu, Z.; Fan, S.; Yang, C.; Zhao, D.; Han, J.; Xiang, H.

10.1101/2024.01.26.577312 — molecular biology — Posted on 2024-01-26

835 WRKY1 confers resistance to powdery mildew by accelerating SAR and preventing over-immunity in apple.

Lan, L.; Cao, L.; Zhang, L.; Fu, W.; Qu, S.; Wang, S.

10.1101/2024.01.24.577112 — molecular biology — Posted on 2024-01-26

836 Variability in HIV-1 Transmitted/Founder Virus Susceptibility to Combined APOBEC3F and APOBEC3G Host Restriction

Gaba, A.; Yousefi, M.; Bhattacharjee, S.; Chelico, L.

10.1101/2024.01.25.577241 — microbiology — Posted on 2024-01-26

837 Fragmented micro-growth habitats present opportunities for alternative competitive outcomes

Batsch, M.; Guex, I.; Todorov, H.; Heiman, C. M.; Vacheron, J.; Vorholt, J.; Keel, C.; van der Meer, J. R.

10.1101/2024.01.26.577336 — microbiology — Posted on 2024-01-26

838 Usutu virus and West Nile virus use a transcellular route of neuroinvasion across an in vitro model of the human blood-brain barrier

Marshall, E. M.; Koopmans, M.; Rockx, B.

10.1101/2024.01.26.577380 — microbiology — Posted on 2024-01-26

839 New insights into the domain of unknown function DUF of EccC5, the pivotal ATPase providing the secretion driving force to the ESX5 secretion system

Ceballos-Zuniga, F.; Menendez, M.; Perez-Dorado, I.

10.1101/2024.01.26.577026 — microbiology — Posted on 2024-01-26

840 The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir

Dinh, T.; Tber, Z.; Rey, J. S.; Mengshetti, S.; Annamalai, A. S.; Haney, R.; Briganti, L.; Amblard, F.; Fuchs, J. R.; Cherepanov, P.; Kim, K.; Schinazi, R. F.; Perilla, J. R.; Kim, B.; Kvaratskhelia, M.

10.1101/2024.01.26.577387 — microbiology — Posted on 2024-01-26

841 Diversity and structure of the deep-sea sponge microbiome in the equatorial Atlantic Ocean

Williams, S. E.; Varliero, G.; Lurgi, M.; Stach, J. E. M.; Race, P. R.; Curnow, P.

10.1101/2024.01.24.577104 — microbiology — Posted on 2024-01-26

842 Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine

Reyes Ballista, J. M.; Hoover, A. J.; Noble, J. T.; Acciani, M. D.; Miazgowicz, K. L.; Harrison, S. A.; Tabscott, G. A. L.; Duncan, A. M.; Barnes, D. N.; Jimenez, A. R.; Brindley, M. A.

10.1101/2024.01.25.577233 — microbiology — Posted on 2024-01-26

843 The alpha4 nicotinic acetylcholine receptor is necessary for the initiation of organophosphate-induced neuronal hyperexcitability

Andrew, P. M.; Feng, W.; Calsbeek, J. J.; Antrobus, S. P.; Cherednychenko, G. A.; MacMahon, J. A.; Bernardino, P. N.; Liu, X.; Harvey, D. J.; Lein, P. J.; Pessah, I.

10.1101/2024.01.24.576980 — pharmacology and toxicology — Posted on 2024-01-26

844 Single-shot Echo Planar Time-resolved Imaging for multi-echo functional MRI and distortion-free diffusion imaging

Dong, Z.; Wald, L. L.; Polimeni, J. R.; Wang, F.

10.1101/2024.01.24.577002 — bioengineering — Posted on 2024-01-26

845 Bridge RNAs direct modular and programmable recombination of target and donor DNA

Durrant, M. G.; Perry, N. T.; Pai, J. J.; Jangid, A. R.; Athukoralage, J. S.; Hiraizumi, M.; McSpedon, J. P.; Pawluk, A.; Nishimasu, H.; Konermann, S.; Hsu, P. D.

10.1101/2024.01.24.577089 — genetics — Posted on 2024-01-26

846 Explaining plant trait variation in response to soil water availability using an optimal height-growth model

Towers, I. R.; O'Reilly Nugent, A.; Sabot, M. E. B.; Vesk, P. A.; Falster, D. S.

10.1101/2024.01.23.576942 — ecology — Posted on 2024-01-26

847 Context-dependent acetylation of the virulence regulator PhoP accounts for carbon-source specific mycobacterial growth inhibition under acidic conditions

Paul, P.; Mehta, K.; Ujjainiya, R.; Bamniya, B.; Thakur, B.; Goar, H.; Sarkar, D.

10.1101/2024.01.25.577197 — microbiology — Posted on 2024-01-26

848 Resolution of ribosomal stalling by ABCF ATPases YfmR and YkpA/YbiT

Takada, H.; Fujiwara, K.; Atkinson, G. C.; Chiba, S.; Hauryliuk, V.

10.1101/2024.01.25.577322 — microbiology — Posted on 2024-01-26

849 Improving Nitrofurantoin Resistance Prediction in Escherichia coli from Whole Genome Sequence by Integrating NfsA/B Enzyme Assays

Dulayangkul, P.; Sealey, J. E.; Lee, W. W.; Reding, C.; Heesom, K. J.; Satapoomin, N.; Williams, P. B.; Avison, M. B.

10.1101/2024.01.25.577238 — microbiology — Posted on 2024-01-26

850 Integrative single-cell multi-omics of CD19CARpos and CARneg T cells suggest drivers of immunotherapy response in B-cell neoplasias

Guerrero-Murillo, M.; Rill-Hinarejos, A.; Trincado, J. L.; Bataller, A.; Ortiz-Maldonado, V.; Benitez-Ribas, D.; Espanol, M.; Gonzalez, E. A.; Martinez-Cibrian, N.; Marchese, D.; Martin-Martin, L.; Garcia-Sancho, A. M.; Heyn, H.; Juan, M.; Urbano-Ispizua, A.; Delgado, J.; Orfao, A.; Mereu, E.; Bueno, C.; Menendez, P.

10.1101/2024.01.23.576878 — immunology — Posted on 2024-01-26

851 The molecular core of transcriptome responses to abiotic stress in plants: a machine learning-driven meta-analysis

Sanchez-Munoz, R.; Depaepe, T.; Samalova, M.; Hejatko, J.; Zaplana, I.; Van Der Straeten, D.

10.1101/2024.01.24.576978 — plant biology — Posted on 2024-01-26

852 Genome-Wide Profiling of Soybean WRINKLED1 Transcription Factor Binding Sites Provides Insight into the Regulation of Fatty Acid and Triacylglycerol Biosynthesis Program in Seeds

Jo, L.; Pelletier, J.; Harada, J. J.

10.1101/2024.01.23.576967 — plant biology — Posted on 2024-01-26

853 Plant response to intermittent heat stress involves modulation of mRNA translation efficiency

Dannfald, A.; Carpentier, M.-C.; Merret, R.; Favory, J.-J.; Deragon, J.-M.

10.1101/2024.01.24.576986 — plant biology — Posted on 2024-01-26

854 On the relationship between afterimages and a simple sensorimotor reaction

Kulakov, A. A.

10.1101/2024.01.23.576541 — physiology — Posted on 2024-01-26

855 Functional studies of deafness-associated pendrin and prestin variants

Takahashi, S.; Kojima, T.; Wasano, K.; Homma, K.

10.1101/2024.01.23.576877 — pathology — Posted on 2024-01-26

856 Community Structure and Function During Periods of High Performance and System Upset in a Full-Scale Mixed Microalgal Wastewater Resource Recovery Facility

Alam, M. M.; Hodaei, M.; Hartnett, E.; Gincley, B.; Khan, F.; Kim, G.-Y.; Pinto, A. J.; Bradley, I. M.

10.1101/2024.01.23.576871 — bioengineering — Posted on 2024-01-26

857 TimberTracer: A Comprehensive Framework for the Evaluation of Carbon Sequestration by Forest Management and Substitution of Harvested Wood Products.

Boukhris, I.; Collalti, A.; Lahssini, S.; Dalmonech, D.; Nakhle, F.; Testolin, R.; Chiricao, M. V.; Santini, M.; Valentini, R.

10.1101/2024.01.24.576985 — ecology — Posted on 2024-01-26

858 A Bayesian overhaul of thermal tolerance landscape models: Predicting ectotherm lethality buildup and survival amid heatwaves

Vajedsamiei, J.; Warlo, N.; Meier, H. E. M.; Melzner, F.

10.1101/2024.01.23.576827 — ecology — Posted on 2024-01-26

859 Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

Klein, B.; Reynolds, M. B.; Xu, B.; Gharaee-Kermani, M.; Gao, Y.; Berthier, C. C.; Henning, S.; Loftus, S. N.; McNeely, K. E.; Victory, A. M.; Dobry, C. J.; Hile, G. A.; Ma, F.; Turnier, J. L.; Gudjonsson, J. E.; O'Riordan, M. X.; Kahlenberg, J. M.

10.1101/2024.01.23.576771 — immunology — Posted on 2024-01-26

860 ATP-Binding Cassette Family C member 1 constrains metabolic responses to high-fat diet in male mice

Villalobos, E.; Miguelez-Crespo, A.; Morgan, R. A.; Ivatt, L.; Kurian, D.; Aguilar, J.; Kline, R. A.; Wishart, T. M.; Morton, N.; Stimson, R. H.; Andrew, R.; Walker, B. R.; Nixon, M.

10.1101/2024.01.23.576896 — physiology — Posted on 2024-01-26

861 Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations

Pacholewska, A.; Lienhard, M.; Brueggemann, M.; Haenel, H.; Bilalli, L.; Koenigs, A.; Becker, K.; Koehrer, K.; Kaiser, J.; Gohlke, H.; Gattermann, N.; Hallek, M.; Herling, C. D.; Koenig, J.; Grimm, C.; Herwig, R.; Zarnack, K.; Schweiger, M. R.

10.1101/2024.01.26.576051 — cancer biology — Posted on 2024-01-26

862 Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of oesophageal cancer

Ganguli, P.; Colomina-Basanta, C.; Mendez, A.; Armero-Pineiro, M.; Zahra, A.; Acha-Sagrado, A.; Misetic, H.; Devonshire, G.; Kelly, G.; Freeman, A.; Green, M.; Nye, E.; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, ; Rodriguez-Justo, M.; Spencer, J.; Fitzgerald, R. C.; Ciccarelli, F. D.

10.1101/2024.01.24.576991 — cancer biology — Posted on 2024-01-26

863 SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis

Coelho, R.; Seashore-Ludlow, B.; Schutz, S.; Christopher Lombardo, F.; Moussaud-Lamodiere, E.; Casanova, R.; Ficek-Pascual, J.; Brunhilde Labrosse, K.; Lopez-Nunez, M.; Rimmer, N.; Fedier, A.; Lima, R.; Montavon Sartorius, C.; Kurzeder, C.; Singer, F.; Bertolini, A.; The TumorProfiler Consortium, ; Ratsch, G.; Bodenmiller, B.; Kallioniemi, O.; Ostling, P.; David, L.; Heinzelmann-Schwarz, V.; Jacob, F.

10.1101/2024.01.24.576987 — cancer biology — Posted on 2024-01-26

864 BMP antagonist CHRDL2 enhances the cancer stem cell phenotype and increases chemotherapy resistance in Colorectal Cancer

Clarkson, E.; Lewis, A.

10.1101/2024.01.23.576664 — cancer biology — Posted on 2024-01-26

865 Dual-targeted nanoparticulate drug delivery systems for enhancing triple-negative breast cancer treatment

Zheng, S.; Li, M.; Xu, W.; Zhang, J.; Li, G.; Xiao, H.; Liu, X.; Shi, J.; Xia, F.; Tian, C.; Kamei, K.-i.

10.1101/2024.01.23.576787 — cancer biology — Posted on 2024-01-26

866 Divergent mechanisms of steroid inhibition in the human {rho}1 GABA(A) receptor

Fan, C.; Cowgill, J.; Howard, R. J.; Lindahl, E.

10.1101/2024.01.23.576874 — biophysics — Posted on 2024-01-26

867 Measurement of solubility product in a model condensate reveals the interplay of small oligomerization and self-association

Chattaraj, A.; Baltaci, Z.; Mayer, B. J.; Loew, L. M.; Ditlev, J. A.

10.1101/2024.01.23.576869 — biophysics — Posted on 2024-01-26

868 Different fluorescent labels report distinct components of spHCN channel voltage sensor movement

Wojciechowski, M. N.; McKenzie, C.; Hung, A.; Kuanyshbek, A.; Forster, I. C.; Soh, M. S.; Reid, C. A.

10.1101/2024.01.23.576936 — biophysics — Posted on 2024-01-26

869 RNA Secondary Structure Prediction Using a Genetic Algorithm with a Selection Method Based on Free Energy Value and Topological Index

Benedetti, G.

10.1101/2024.01.24.576993 — bioinformatics — Posted on 2024-01-26

870 Robust Evaluation of Deep Learning-based Representation Methods for Survival and Gene Essentiality Prediction on Bulk RNA-seq Data

Gross, B.; Dauvin, A.; Cabeli, V.; Kmetzsch, V.; El Khoury, J.; Dissez, G.; Ouardini, K.; Grouard, S.; Davi, A.; Loeb, R.; Esposito, C.; Hulot, L.; Ghermi, R.; Blum, M.; Darhi, Y.; Durand, E. Y.; Romagnoni, A.

10.1101/2024.01.23.576852 — bioinformatics — Posted on 2024-01-26

871 The interplay between moult of flight feathers and fuelling conducted on the breeding grounds of the Great Snipe Gallinago media from the eastern European, lowland population

Witkowska, M.; Korniluk, M.; Pinchuk, P.; Tumiel, T.; Karlionova, N.; Meissner, W.

10.1101/2024.01.23.576834 — ecology — Posted on 2024-01-26

872 ER-located PIN5 transporter generates potent auxin sinks driven by the IAA decarboxylation pathway

Covanova, M.; Muller, K.; Klierova, N.; Abdollahi Sisi, N.; Skupa, P.; Smetana, O.; Dobrev, P. I.; Ruzicka, K.; Petrasek, J.

10.1101/2024.01.24.576992 — plant biology — Posted on 2024-01-26

873 Predicting the Assembly Order of Protein Complexes by Multi-Temperature Coarse-Grained Simulations

Lu, Y.; Liu, X.; Zhang, Z.

10.1101/2024.01.24.576999 — biophysics — Posted on 2024-01-26

874 Peptidoform analysis of IP-MS data allows detection of differentially present bait proteoforms

Sdelci, S.; Sdelci, S.; Kourtis, S.; Cianferoni, D.; Serrano, L.

10.1101/2024.01.23.576810 — bioinformatics — Posted on 2024-01-26

875 Large-Scale COI Gene Data Analysis for the Development of a Gel-Based Multiplex PCR Test Capable of Identifying Biting Midge Vector Species and Haplotypes (Diptera: Ceratopogonidae) of the Culicoides subgenus Avaritia Fox, 1955

Dähn, O.; Werner, D.; Mathieu, B.; Kampen, H.

10.1101/2024.01.23.576915 — genetics — Posted on 2024-01-26

876 Fundamental constraints on the evolution of vertebrate life histories

Brooks, G.; Uyeda, J.; Bone, N.; Conrad, H.; Mull, C.; Kindsvater, H.

10.1101/2024.01.23.576873 — evolutionary biology — Posted on 2024-01-26

877 Maternal manipulation of offspring size can trigger the evolution of eusociality in promiscuous species

Rees-Baylis, E.; Pen, I.; Kreider, J. J.

10.1101/2024.01.23.576864 — evolutionary biology — Posted on 2024-01-26

878 Global heterogeneity of latitudinal patterns in herbivory between native and exotic plants

Guo, Y.; Parepa, M.; Wang, H.; Wang, M.; Wu, J.; Li, B.; Ju, R.-T.; Bossdorf, O.

10.1101/2024.01.24.576872 — ecology — Posted on 2024-01-26

879 Relationship between extreme species richness and Holocene persistence of forest-steppe grasslands in Transylvania, Romania

Novak, J.; Samonil, P.; Rolecek, J.

10.1101/2024.01.23.576840 — ecology — Posted on 2024-01-26

880 Food web structure mediate positive and negative effects of diversity on ecosystem functioning in a large floodplain river

Borzone Mas, D.; Scarabotti, P. A.; Alvarenga, P.; Vaschetto, P. A.; Arim, M.

10.1101/2024.01.24.576859 — ecology — Posted on 2024-01-26

881 Large language models overcome the challenges of unstructured text data in ecology

Castro, A.; Pinto, J.; Reino, L.; Pipek, P.; Capinha, C.

10.1101/2024.01.23.576654 — ecology — Posted on 2024-01-26

882 Can't carve air, can't weave names: Plant species used in Colombian artisan crafts are not equally assessed for vulnerability at the international and national level

Hernandez, K. V.; Andrade-Rivas, F.; Zapata, F.; Batista, N.; Cardenas-Navarrete, A.; Davila Arenas, A.; Herrera-R, G. A.; Langhans, K. E.; Levey, D.; Neill, A.; Nguyen, O.; Ocampo-Penuela, N.; Sanchez Lopez, S.; Echeverri, A.

10.1101/2024.01.24.573691 — ecology — Posted on 2024-01-26

883 Differential encoding of fear learning and fear expression in the ventral and dorsal hippocampus

Pompili, M. N.; Hamou, N.; Wiener, S. I.

10.1101/2024.01.26.577384 — neuroscience — Posted on 2024-01-26

884 Vagus nerve stimulation (VNS) modulates synaptic plasticity in the rat infralimbic cortex via Trk-B receptor activation to reduce drug-seeking

Driskill, C. M.; Childs, J. E.; Phensy, A. J.; Rodriguez, S. R.; O'Brien, J. T.; Lindquist, K. L.; Naderi, A. O.; Bordieanu, B.; McGinty, J. F.; Kroener, S.

10.1101/2024.01.25.577293 — neuroscience — Posted on 2024-01-26

885 A reduced vernalization requirement is a key component of the early-bolting trait in globe artichoke (Cynara cardunculus var. scolymus)

Berentsen, R.; Benlloch, R.; Visser, P.; Madueno, F.; Balanza, V.

10.1101/2024.01.23.576919 — plant biology — Posted on 2024-01-26

886 Beav: A bacterial genome and mobile element annotation pipeline

Jung, J. M.; Rahman, A.; Schiffer, A. M.; Weisberg, A. J.

10.1101/2024.01.25.577299 — bioinformatics — Posted on 2024-01-26

887 Supercontinuum intrinsic fluorescence imaging heralds free view of living systems

Wang, G.; Tu, H.

10.1101/2024.01.26.577383 — bioengineering — Posted on 2024-01-26

888 MAARU: Multichannel Acoustic Autonomous Recording Unit for spatial ecosystem monitoring.

Heath, B. E.; Le Penru, N. P.; Skinner, J.; Orme, C. D. L.; Sethi, S. S.; Ewers, R. M.; Picinali, L.

10.1101/2024.01.23.576628 — ecology — Posted on 2024-01-26

889 Herpes Simplex Virus-1 targets the 2-3cGAMP importer SLC19A1 as an antiviral countermeasure.

Szemere, Z. K.; Murphy, E. A.

10.1101/2024.01.24.577105 — microbiology — Posted on 2024-01-26

890 In silico assessment of immune cross protection between BCoV and SARS-CoV-2

Beirao, B. C. B.; Querne, L. B.; Zettel Bastos, F.; Adur, M. d. A.; Cavalheiro, V. L.

10.1101/2024.01.25.577193 — immunology — Posted on 2024-01-26

891 Degenerative and regenerative peripheral processes are associated with persistent painful chemotherapy-induced neuropathies in males and females

Naratadam, G.; Mecklenburg, J.; Shein, S.; Zou, Y.; Lai, Z.; Tumanov, A.; Price, T. J.; Akopian, A.

10.1101/2024.01.25.577218 — neuroscience — Posted on 2024-01-26

892 Superagers resist typical age-related white matter structural changes

Garo-Pascual, M.; Zhang, L.; Valenti-Soler, M.; Strange, B.

10.1101/2024.01.25.577227 — neuroscience — Posted on 2024-01-26

893 Breaking free from the clocks tyranny restores memory to brain damaged flies

Dissel, S.; Morgan, E.; Cao, L.; Wakefield, Z. P.; Shetty, S.; Chan, D.; Duong, V.; Donlea, J. M.; Farah, H.; Loutrianakis, V.; Ford, M.; Streett, L.; Periandri, E.; Li, Z.; Huang, I.; Abdalla, D.; Kalra, A.; Sousani, L.; Holder, B.; McAdams, C.; van Swinderen, B.; Shaw, P. J.

10.1101/2024.01.25.577231 — neuroscience — Posted on 2024-01-26

894 Spyglass: a data analysis framework for reproducible and shareable neuroscience research

Lee, K. H.; Denovellis, E. L.; Ly, R.; Magland, J.; Soules, J.; Comrie, A. E.; Gramling, D. P.; Guidera, J. A.; Nevers, R.; Adenekan, P.; Brozdowski, C.; Bray, S.; Monroe, E.; Bak, J. H.; Coulter, M.; Sun, X.; Tritt, A.; Oliver Ruebel, O.; Nguyen, T.; Yatsenko, D.; Chu, J.; Kemere, C.; Garcia, S.; Buccino, A.; Frank, L. M.

10.1101/2024.01.25.577295 — neuroscience — Posted on 2024-01-26

895 Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice

Hackwell, E. C. R.; Ladyman, S. R.; Clarkson, J.; McQullian, H. J.; Boehm, U.; Herbison, A. E.; Brown, R. S. E.; Grattan, D. R.

10.1101/2024.01.26.577359 — neuroscience — Posted on 2024-01-26

896 Detection of cell assemblies in high-density extracellular electrophysiological recordings

Makdah, G.; Wiener, S. I.; Pompili, M. N.

10.1101/2024.01.26.577338 — neuroscience — Posted on 2024-01-26

897 Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities

Erb, M. L.; Sipple, K.; Levine, N.; Chen, X.; Moore, D. J.

10.1101/2024.01.25.577280 — neuroscience — Posted on 2024-01-26

898 The Temporal Dynamics of Aperiodic Neural Activity Track Changes in Sleep Architecture

Ameen, M. S.; Jacobs, J.; Schabus, M.; Hoedlmoser, K.; Donoghue, T.

10.1101/2024.01.25.577204 — neuroscience — Posted on 2024-01-26

899 Functional brain adaptations during speech processing in 4-month-old bilingual infants

Blanco, B.; Molnar, M.; Arrieta, I.; Caballero-Gaudes, C.; Carreiras, M.

10.1101/2024.01.26.577342 — neuroscience — Posted on 2024-01-26

900 Amplifying post-stimulation oscillatory dynamics by engaging synaptic plasticity with periodic stimulation: a modelling study

Lefebvre, J.; Pariz, A.

10.1101/2024.01.25.577245 — neuroscience — Posted on 2024-01-26

901 Inhibitory control of gait initiation in humans: an electroencephalography study

Ziri, D.; Hugueville, L.; Olivier, C.; Boulinguez, P.; Gunasekaran, H.; Lau, B.; Welter, M.-L.; GEORGE, N.

10.1101/2024.01.25.577273 — neuroscience — Posted on 2024-01-26

902 Hippocampal reactive neural stem cells are able to phagocytose and have an immunological molecular signature

Abiega, O.; Senovilla-Ganzo, R.; El-Ouraoui, M.; Muro, T.; Ruiz, L.; Fitzsimons, C. P.; Martin Suarez, S.; Encinas Perez, J. M.

10.1101/2024.01.26.577346 — neuroscience — Posted on 2024-01-26

903 Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries

Criado-Marrero, M.; Ravi, S.; Bhaskar, E.; Barroso, D.; Pizzi, M. A.; Williams, L.; Wellington, C. L.; Febo, M.; Abisambra, J. F.

10.1101/2024.01.25.577316 — neuroscience — Posted on 2024-01-26

904 Leptin Activated Hypothalamic BNC2 Neurons Acutely Suppress Food Intake

Tan, H. L.; Yin, L.; Tan, Y.; Ivanov, J.; Plucinska, K.; Ilanges, A.; Herb, B. R.; Wang, P.; Kosse, C.; Cohen, P.; Lin, D.; Friedman, J. M.

10.1101/2024.01.25.577315 — neuroscience — Posted on 2024-01-26

905 Cortical representational geometry of diverse tasks reveals subject-specific and subject-invariant cognitive structures

Nakai, T.; Kubo, R.; Nishimoto, S.

10.1101/2024.01.26.577334 — neuroscience — Posted on 2024-01-26

906 Neurocan regulates axon initial segment organization and neuronal activity in cultured cortical neurons

Baidoe-Ansah, D.; Mirzapourdelavar, H.; Aleshin, S.; Schott, B. H.; Seidenbecher, C.; Kaushik, R.; Dityatev, A. I.

10.1101/2024.01.26.577401 — neuroscience — Posted on 2024-01-26

907 Exposure to epoxiconazole induces hyperlocomotion in adult zebrafish

Reis, C. G.; Chitolina, R.; Bastos, L. M.; Portela, S. M.; Stahlhofer-Buss, T.; Piato, A.

10.1101/2024.01.25.577223 — neuroscience — Posted on 2024-01-26

908 Microalgal biofilm induces larval settlement in the model marine worm Platynereis dumerilii

Hird, C.; Jekely, G.; Williams, E. A.

10.1101/2024.01.23.576855 — zoology — Posted on 2024-01-26

909 Exploring the Categorical Nature of Colour Perception: Insights from Deep Networks

Akbarinia, A.

10.1101/2024.01.25.577209 — animal behavior and cognition — Posted on 2024-01-26

910 Characterisation of laminar and vascular spatiotemporal dynamics of CBV and BOLD signals using VASO and ME-GRE at 7T in humans

Dresbach, S.; Huber, L. R.; Gulban, O. F.; Pizzuti, A.; Trampel, R.; Ivanov, D.; Weiskopf, N.; Goebel, R. W.

10.1101/2024.01.25.576050 — neuroscience — Posted on 2024-01-26

911 High-dimensional cortical signals reveal rich bimodal and working memory-like representations among S1 neuron populations

Kristensen, S. S.; Kesgin, K.; Jorntell, H.

10.1101/2024.01.26.577171 — neuroscience — Posted on 2024-01-26

912 Efficient Inference on a Network of Spiking Neurons using Deep Learning

Baldy, N.; Breyton, M.; Woodman, M. M.; Jirsa, V. K.; Hashemi, M.

10.1101/2024.01.26.577077 — neuroscience — Posted on 2024-01-26

913 Regional specialization manifests in the reliability of neural population codes

Guidera, J. A.; Gramling, D. P.; Comrie, A. E.; Joshi, A.; Denovellis, E. L.; Lee, K. H.; Zhou, J.; Thompson, P.; Hernandez, J.; Yorita, A.; Haque, R.; Kirst, C.; Frank, L. M.

10.1101/2024.01.25.576941 — neuroscience — Posted on 2024-01-26

914 Epitranscriptomic Reader YTHDF2 Regulates SEK1(MAP2K4)-JNK-cJUN Inflammatory Signaling in Astrocytes during Neurotoxic Stress

Malovic, E.; Ealy, A.; Hsu, P. J.; Sarkar, S.; Miller, C.; Rokad, D.; Goeser, C.; Hartman, A. K.; Zhu, A.; Palanisamy, B.; Zenitsky, G.; Jin, H.; Anantharam, V.; Kanthasamy, A.; He, C.; Kanthasamy, A.

10.1101/2024.01.26.577106 — neuroscience — Posted on 2024-01-26

915 Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS

Thiry, L.; Sirois, J.; Durcan, T. M.; Stifani, S.

10.1101/2024.01.25.577189 — neuroscience — Posted on 2024-01-26

916 Optogenetic silencing hippocampal inputs to the retrosplenial cortex causes a prolonged disruption of working memory

Pinto-Correia, B.; Caldeira, P.; Remondes, M.

10.1101/2024.01.26.577365 — neuroscience — Posted on 2024-01-26

917 A Hill type equation reveals the regulation principle of target protein expression led by p53 pulsing

Shi, X.

10.1101/2023.10.24.563713 — systems biology — Posted on 2024-01-26

918 First-in-human demonstration of floating EMG sensors and stimulators wirelessly powered and operated by volume conduction

Becerra-Fajardo, L.; Minguillon, J.; Krob, M. O.; Rodrigues, C.; Gonzalez-Sanchez, M.; Megia-Garcia, A.; Redondo Galan, C.; Gutierrez Henares, F.; Comerma, A.; del-Ama, A. J.; Gil-Agudo, A.; Grandas, F.; Schneider-Ickert, A.; Oliveira Barroso, F.; Ivorra, A.

10.1101/2023.06.30.547056 — bioengineering — Posted on 2024-01-26

919 Amino acid characteristics in protein native state structures

Skrbic, T.; Giacometti, A.; Hoang, T. X.; Maritan, A.; Banavar, J. R.

10.1101/2023.12.12.571261 — biophysics — Posted on 2024-01-26

920 Semi-supervised learning while controlling the FDR with an application to tandem mass spectrometry analysis

Freestone, J. A.; Käll, L.; Noble, W. S.; Keich, U.

10.1101/2023.10.26.564068 — bioinformatics — Posted on 2024-01-26

921 Investigating the Role of Neck Muscle Activation and Neck Damping Characteristics in Brain Injury Mechanism

Bahreinizad, H.; Chowdhury, S.

10.1101/2023.11.15.567289 — bioengineering — Posted on 2024-01-26

922 The bacterial microbiome of symbiotic and menthol-bleached polyps of Galaxea fascicularis in captivity

Puntin, G.; Wong, J. C.-Y.; Roethig, T.; Baker, D. M.; Sweet, M.; Ziegler, M.

10.1101/2023.08.23.554380 — microbiology — Posted on 2024-01-26

923 CytoPipeline & CytoPipelineGUI: An R package suite for building and visualizing automated pre-processing pipelines for flow cytometry data

Hauchamps, P.; Bayat, B.; Delandre, S.; Hamrouni, M.; Toussaint, M.; Temmerman, S.; Lin, D.; Gatto, L.

10.1101/2023.10.10.561699 — bioinformatics — Posted on 2024-01-26

924 A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell derived cardiomyocytes

Seguret, M.; Davidson, P.; Robben, S.; Jouve, C.; Pereira, C.; Lelong, Q.; Deshayes, L.; Cerveau, C.; Le Berre, M.; Rodrigues Ribeiro, R. S.; Hulot, J.-S.

10.1101/2023.03.26.534303 — bioengineering — Posted on 2024-01-26

925 CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development

Bulger, E. A.; McDevitt, T. C.; Bruneau, B. G.

10.1101/2024.01.25.577277 — developmental biology — Posted on 2024-01-26

926 Excessive F-Actin and Microtubule Formation Mediates Primary Cilia Shortening and Loss in Response to Increased Extracellular Osmotic Pressure

Otani, H.; Nakazato, R.; Ijaz, F.; Koike, K.; Ikegami, K.

10.1101/2024.01.25.577175 — cell biology — Posted on 2024-01-26

927 Yellow and oxidation-resistant derivatives of a monomeric superfolder GFP

Valbuena, F. M.; Krahn, A. H.; Tokamov, S. A.; Greene, A. C.; Fehon, R. G.; Glick, B. S.

10.1101/2024.01.25.577236 — cell biology — Posted on 2024-01-26

928 A senescence-specific lncRNA controls metabolic rewiring of senescent cells

Grossi, E.; Marchese, F. P.; Gonzalez, J.; Goni, E.; Amadoz, A.; Herranz, N.; Puchades-Carrasco, L.; Montes, M.; Huarte, M.

10.1101/2024.01.25.577153 — cell biology — Posted on 2024-01-26

929 Modulation of circadian rhythms in articular cartilage by heat pulses

Goncalves, C. F.; Dudek, M.; Pathiranage, D. R.; Paszek, A.; El-Houni, Z.; Li, S.; Tawy, G.; Biant, L.; Hoyland, J. A.; Meng, Q.-J.

10.1101/2024.01.26.577368 — cell biology — Posted on 2024-01-26

930 Tracking exocytic vesicle movements with MSP-tracker/viewer reveals the spatial control of secretion in epithelial cells.

Richens, J. H.; Dmitrieva, M.; Zenner, H. L.; Muschalik, N.; Butler, R.; Glashauser, J.; Camelo, C.; Luschnig, S.; Munro, S.; Rittscher, J.; St Johnston, D.

10.1101/2024.01.25.577201 — cell biology — Posted on 2024-01-26

931 CHMP4B contributes to maintaining the follicular cells integrity in the panoistic ovary of the cockroach Blattella germanica

Farrus, N.; Maestro, J. L.; Piulachs, M. D.

10.1101/2024.01.24.577052 — cell biology — Posted on 2024-01-26

932 Oscillatory Hypoxia Induced Unfolded Protein Folding Response Gene Expression Predicts Low Survival in Human Breast Cancer Patients

Suhail, Y.; Liu, Y.; Du, W.; Afzal, J.; Atiq, A.; Kshitiz,

10.1101/2024.01.25.577274 — cancer biology — Posted on 2024-01-26

933 Diffraction minima resolve point scatterers at tiny fractions (1/80) of the wavelength

Hensel, T. A.; Wirth, J. O.; Hell, S. W.

10.1101/2024.01.24.576982 — biophysics — Posted on 2024-01-26

934 P66Shc Mediates SUMO2-induced Endothelial Dysfunction

Kumar, J.; Uppulapu, s. K.; Kumari, S.; Sharma, K.; Paradee, W. J.; Yadav, R. P.; Kumar, V.; Kumar, S.

10.1101/2024.01.24.577109 — cell biology — Posted on 2024-01-26

935 Mdivi-1 affects neuronal activity by inhibition of Complex I and respiratory supercomplex assembly

Marx, N.; Ritter, N.; Disse, P.; Seebohm, G.; Busch, K. B.

10.1101/2024.01.25.577160 — cell biology — Posted on 2024-01-26

936 Functional impairment of "helpless" CD8+ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

van der Heide, V.; Davenport, B.; Cubitt, B.; Roudko, V.; Choo, D.; Humblin, E.; Jhun, K.; Angeliadis, K.; Dawson, T.; Furtado, G.; Kamphorst, A. O.; Ahmed, R.; de la Torre, J. C.; Homann, D.

10.1101/2024.01.22.576725 — immunology — Posted on 2024-01-26

937 Adenoviral Delivery of the CIITA Transgene Induces T-Cell-Mediated Killing in Glioblastoma Organoids

Salvato, I.; Klein, E.; Poli, A.; Rezaeipour, M.; Ermini, L.; Nosirov, B.; Lipsa, A.; Oudin, A.; Baus, V.; Dore, G. M.; Cosma, A.; Golebiewska, A.; Niclou, S. P.; Marchini, A.

10.1101/2024.01.22.576747 — cancer biology — Posted on 2024-01-26

938 Activity-driven chromatin organization during interphase: compaction, segregation, and entanglement suppression

Chan, B.; Rubinstein, M.

10.1101/2024.01.22.576729 — biophysics — Posted on 2024-01-26

939 The endophytic fungus Serendipita indica alters auxin distribution in Arabidopsis thaliana roots through alteration of auxin transport and conjugation to promote plant growth

Gonzalez Ortega-Villaizan, A.; King, E.; Patel, M. K.; PEREZ ALONSO, M. M.; Scholz, S. S.; Sakakibara, H.; Kiba, T.; Kojima, M.; Takebayashi, Y.; Ramos, P.; Morales-Quintana, L.; Breitenbach, S.; Smolko, A.; Salopek-Sondi, B.; Bauer, N.; Müller-Ludwig, J.; Krapp, A.; Oelmüller, R.; Vicente-Carbajosa, J.; Pollmann, S.

10.1101/2024.01.23.576781 — plant biology — Posted on 2024-01-26

940 Prognostic Significance of preoperative serum CA125, CA19-9, CA72-4, CEA, and AFP in Patients with Endometrial cancer

Wang, Z.-h.; Zhang, Y.-z.; Ge, S.-w.; Shan, L.-h.; Wang, B.; Zhang, Z.-y.; Wu, Q.-j.; Ma, X.-x.

10.1101/2024.01.23.576857 — cancer biology — Posted on 2024-01-26

941 Interface-aware molecular generative framework for protein-protein interaction modulators

Wang, J.; Mao, J.; Li, C.; Xiang, H.; Wang, X.; Wang, S.; Wang, Z.; Chen, Y.; Li, Y.; Sun, H.; No, K. T.; Song, T.; Zeng, X.

10.1101/2023.10.10.557742 — bioinformatics — Posted on 2024-01-26

942 Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein Variants

Chamness, L. M.; Kuntz, C. P.; McKee, A. G.; Penn, W. D.; Hemmerich, C. M.; Rusch, D. B.; Woods, H.; Dyotima, ; Meiler, J.; Schlebach, J. P.

10.1101/2023.08.25.554866 — biochemistry — Posted on 2024-01-26

943 A diversity of diversities: do complex environmental effects underpin associations between below- and aboveground taxa?

Seaton, F. M.; George, P. B.; Alison, J.; Jones, D. L.; Creer, S.; Smart, S. M.; Emmett, B.; Robinson, D. A.

10.1101/2023.06.07.544003 — ecology — Posted on 2024-01-26

944 Gap junction and amino acid import in somatic cells promote germ cell growth

Vachias, C.; Tourlonias, C.; Grelee, L.; Gueguen, N.; Renaud, Y.; Richard, G.; Venugopal, P.; Pouchin, P.; Brasset, E.; Mirouse, V.

10.1101/2023.05.15.540837 — developmental biology — Posted on 2024-01-26

945 LRH-1/NR5A2 Activation in Immune Cells from Individuals with Type 1 Diabetes Mellitus Mitigates Inflammation via Immunometabolic Reprogramming and Enhanced Human Islet Function in Mice

Cobo-vuilleumier, N.; Rodriguez-Fernandez, S.; Lopez-Noriega, L.; Lorenzo, P. I.; Franco, J. M.; Lachaud, c. C.; Martin-Vazquez, E.; Araujo Legido, R.; Dorronsoro, A.; Lopez-Fernandez-Sobrino, R.; Fernandez-santos, b.; Salas-Lloret, D.; van Overbeek, N.; Ramos-Rodriguez, M.; Mateo-Rodriguez, C.; Hidalgo, L.; Nano, R.; Arroba, A. I.; Campos Caro, A.; Vertegaal, A. C.; Martin Montalvo, A.; Martin, F.; Aguilar-Diosdado, M.; Piemonti, L.; Pasquali, L.; Gonzalez Prieto, R.; Garcia Sanchez, M. I.; Martinez-Brocca, M.; Vives-Pi, M.; Gauthier, B. R.

10.1101/2023.09.18.558230 — cell biology — Posted on 2024-01-26

946 Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration

Merta, H.; Isogai, T.; Paul, B.; Danuser, G.; Henne, W. M.

10.1101/2024.01.24.577043 — cell biology — Posted on 2024-01-26

947 Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer

Wortmann, E.; Osswald, A.; Wylensek, D.; Kuhls, S.; Coleman, O.; Ducarmon, Q.; Liang, W.; Treichel, N.; Schumacher, F.; Volet, C.; Matysik, S.; Kleigrewe, K.; Gigl, M.; Rohn, S.; Kleuser, B.; Liebisch, G.; Schnieke, A.; Bernier-Latmani, R.; Zeller, G.; Haller, D.; Flisikowski, K.; Ocvirk, S.; Clavel, T.

10.1101/2023.03.17.533140 — microbiology — Posted on 2024-01-26

948 Branch-specific clustered parallel fiber input controls dendritic computation in Purkinje cells

Cirtala, G.; De Schutter, E.

10.1101/2024.01.25.577146 — neuroscience — Posted on 2024-01-26

949 Dynamic noise estimation: A generalized method for modeling noise fluctuations in decision-making

Li, J.-J.; Shi, C.; Li, L.; Collins, A.

10.1101/2023.06.19.545524 — neuroscience — Posted on 2024-01-26

950 Distinct causes underlie double-peaked trilobite morphological disparity

Drage, H. B.; Pates, S.

10.1101/2024.01.05.574297 — paleontology — Posted on 2024-01-26

951 Probing the Link Between Vision and Language in Material Perception

Liao, C.; Sawayama, M.; Xiao, B.

10.1101/2024.01.25.577219 — neuroscience — Posted on 2024-01-26

952 Synaptic vesicle release regulates pre-myelinating oligodendrocyte-axon interactions in a neuron subtype-specific manner

Gronseth, J. R.; Nelson, H. N.; Johnson, T. L.; Mallon, T. A.; Martell, M. R.; Pfaffenbach, K. A.; Duxbury, B. B.; Henke, J. T.; Treichel, A. J.; Hines, J. H.

10.1101/2024.01.25.577297 — neuroscience — Posted on 2024-01-26

953 LORE receptor homomerization is required for 3-hydroxydecanoic acid-induced immune signaling and determines the natural variation of immunosensitivity within the Arabidopsis genus

Eschrig, S.; Schaeffer, M.; Shu, L.-J.; Illig, T.; Eibel, S.; Fernandez, A.; Ranf, S.

10.1101/2021.09.27.461997 — plant biology — Posted on 2024-01-26

954 Human stem cell model of neural crest cell differentiation reveals a requirement of SF3B4 in survival, maintenance, and differentiation

Griffin, C.; Saint-Jeannet, J.-P.

10.1101/2024.01.25.577202 — developmental biology — Posted on 2024-01-26

955 In vitro neutrophil-bacteria assay in whole blood microenvironments with single-cell confinement

Li, C.; Hendrikse, N. W.; Argall-Knapp, Z.; Mai, M.; Kim, J. S.

10.1101/2024.01.22.576723 — biophysics — Posted on 2024-01-26

956 Pseudotime analysis for time-series single-cell sequencing and imaging data

Li, G.; Kim, H.-J.; Pendyala, S.; Zhang, R.; Disteche, C. M.; Vert, J.-P.; Deng, X.; Fowler, D. M.; Noble, W. S.

10.1101/2023.11.03.565575 — genomics — Posted on 2024-01-26

957 Mycobacterium smegmatis NucS-promoted DNA Mismatch Repair involves limited resection by a 5'-3' exonuclease and is independent of homologous recombination and NHEJ

Rivera-Flores, I. V.; Wang, E. X.; Murphy, K. C.

10.1101/2023.11.26.568737 — genetics — Posted on 2024-01-26

958 A geometric parameterization for beta turns

Newell, N. E.

10.1101/2024.01.01.573818 — molecular biology — Posted on 2024-01-26

959 Eukaryotic genomic data uncover an extensive host range of mirusviruses

Zhao, H.; Meng, L.; Hikida, H.; Ogata, H.

10.1101/2024.01.18.576163 — microbiology — Posted on 2024-01-26

960 N-terminal acetylation separately promotes nuclear localization and host shutoff activity of the influenza A virus ribonuclease PA-X

Daly, R. E.; Myasnikov, I.; Gaglia, M. M.

10.1101/2023.12.01.569683 — microbiology — Posted on 2024-01-26

961 Virtual electrode or virtual scalpel? A cancellation-based approach to data analysis and source localization.

de Cheveigne, A.

10.1101/2023.09.19.558390 — neuroscience — Posted on 2024-01-26

962 Developmental trajectories and differences in functional brain network properties of preterm and at-term neonates

Lopez Guerrero, N. G.; Alcauter, S.

10.1101/2023.11.24.568614 — neuroscience — Posted on 2024-01-26

963 Neural predictors of subjective fear depend on the situation

Wang, Y.; Kragel, P. A.; Satpute, A. B.

10.1101/2022.10.20.513114 — neuroscience — Posted on 2024-01-26

964 Cross-regulation between proteome reallocation and metabolic flux redistribution governs bacterial growth transition kinetics

Yuan, H.; Bai, Y.; Li, X.; Fu, X.

10.1101/2023.07.06.547923 — systems biology — Posted on 2024-01-26

965 Ryanodine Receptor Stabilization Therapy Suppresses Ca2+- Based Arrhythmias in a Novel Model of Metabolic HFpEF

Kaplan, A. D.; Boyman, L.; Ward, C. W.; Lederer, W. J.; Greiser, M.

10.1101/2023.06.21.544411 — physiology — Posted on 2024-01-26

966 Generalizable features for the diagnosis of infectious disease, autoimmunity and cancer from adaptive immune receptor repertoires

Xu, Z.; Ismanto, H. S.; Saputri, D. S.; Haruna, S.; Sun, G.; Wilamowski, J.; Teraguchi, S.; Sengupta, A.; Standley, D. M.

10.1101/2023.11.28.569125 — bioinformatics — Posted on 2024-01-25

967 MapTurns: mapping the structure, H-bonding and contexts of beta turns in proteins

Newell, N. E.

10.1101/2024.01.02.573949 — bioinformatics — Posted on 2024-01-26

968 Examining population structure across multiple collections of Cannabis

Halpin-McCormick, A.; Heyduk, K.; Kantar, M.; Batora, N. L.; Masalia, R.; Law, K.; Kuntz, E.

10.1101/2022.07.09.499013 — genomics — Posted on 2024-01-25

969 Interplay between fecundity, sexual and growth selection on the spring phenology of European beech (Fagus sylvatica L.).

Oddou-Muratorio, S.; Bontemps, A.; Gauzere, J.; Klein, E. K.

10.1101/2023.04.27.538521 — evolutionary biology — Posted on 2024-01-26

970 IDENTIFICATION OF AN EARLY SUBSET OF CEREBELLAR NUCLEI NEURONS IN MICE

Rahimi-Balaei, M.; Amiri, S.; Lamonerie, T.; Wu, S.-R.; Zoghbi, H. Y.; Consalez, G. G.; Goldowitz, D.; Marzban, H.

10.1101/212571 — developmental biology — Posted on 2024-01-25

971 HIV-1 Vpr-induced DNA damage activates NF-κB through ATM-NEMO independent of cell cycle arrest

Sandoval, C.; Nisson, K.; Fregoso, O. I.

10.1101/2023.05.23.541990 — microbiology — Posted on 2024-01-25

972 Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years

Finley, A. J.; Angus, D. J.; Knight, E.; van Reekum, C. M.; Lachman, M. E.; Davidson, R. J.; Schaefer, S. M.

10.1101/2023.07.17.549371 — neuroscience — Posted on 2024-01-25

973 The Lifespan Trajectories of Brain Activity Related to Cognitive Control: A Meta-Analytic Study

Yang, G.; Li, Z.; Petersen, I. T.; Wang, L.; Radua, J.; Liu, X.

10.1101/2023.08.20.554018 — neuroscience — Posted on 2024-01-25

974 Rab11 suppresses neuronal stress signaling by localizing Dual leucine zipper kinase to axon terminals for protein turnover.

Kim, S.; Quagraine, Y.; Singh, M.; Kim, J. H.

10.1101/2023.04.18.537392 — neuroscience — Posted on 2024-01-25

975 The blast pathogen effector AVR-Pik binds and stabilizes rice heavy metal-associated (HMA) proteins to co-opt their function in immunity

Oikawa, K.; Fujisaki, K.; Shimizu, M.; Takeda, T.; Nemoto, K.; Saitoh, H.; Hirabuchi, A.; Hiraka, Y.; Miyaji, N.; Białas, A.; Langner, T.; Kellner, R.; Bozkurt, T. O.; Cesari, S.; Kroj, T.; Banfield, M. J.; Kamoun, S.; Terauchi, R.

10.1101/2020.12.01.406389 — plant biology — Posted on 2024-01-25

976 Accurate quantification of single-cell and single-nucleus RNA-seq transcripts using distinguishing flanking k-mers

Eldjarn Hjörleifsson, K.; Sullivan, D. K.; Swarna, N. P.; Holley, G.; Melsted, P.; Pachter, L.

10.1101/2022.12.02.518832 — bioinformatics — Posted on 2024-01-25

977 ExploreTurns: A web tool for the exploration, analysis, and retrieval of beta turns and their contexts in proteins; application to beta-bulge loops, Schellman loops, Asx helix caps and other hydrogen-bonded motifs

Newell, N. E.

10.1101/2024.01.01.573820 — bioinformatics — Posted on 2024-01-25

978 Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism

Nshanian, M.; Geller, B. S.; Gruber, J. J.; Chleilat, F.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.

10.1101/2024.01.11.575111 — genetics — Posted on 2024-01-25

979 Plasticity-led and mutation-led evolutions are different modes of the same developmental gene regulatory network

Ng, E. T. H.; Kinjo, A. R.

10.1101/2023.11.08.566329 — evolutionary biology — Posted on 2024-01-25

980 High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes

Zhang, L. A.; Li, P.; Callaway, E.

10.1101/2024.01.23.576944 — neuroscience — Posted on 2024-01-25

981 Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy

Leng, K.; Cadwell, C. R.; Devine, W. P.; Tihan, T.; Qi, Z.; Singhal, N.; Glenn, O.; Kamiya, S.; Wiita, A.; Berger, A.; Shieh, J.; Titus, E.; Paredes, M.; Upadhyay, V.

10.1101/2023.10.16.562560 — neuroscience — Posted on 2024-01-25

982 Disuse-driven plasticity in the human thalamus and putamen

Chauvin, R. J.; Newbold, D. J.; Nielsen, A. N.; Miller, R. L.; Krimmel, S. R.; Metoki, A.; Wang, A.; Van, A. N.; Montez, D. F.; Marek, S.; Suljic, V.; Baden, N. J.; Ramirez-Perez, N.; Scheidter, K. M.; Monk, J. S.; Whiting, F. I.; Adeyemo, B.; Snyder, A. Z.; Kay, B. P.; Raichle, M. E.; Laumann, T. O.; Gordon, E. M.; Dosenbach, N. U. F.

10.1101/2023.11.07.566031 — neuroscience — Posted on 2024-01-25

983 Unravelled proteins form blobs during translocation across nanopores

Sauciuc, A.; Whittaker, J. J.; Tadema, M. J.; Tych, K. M.; Guskov, A.; Maglia, G.

10.1101/2024.01.23.576815 — biophysics — Posted on 2024-01-25

984 Repeated horizontal acquisition of lagriamide-producing symbionts in Lagriinae beetles

Uppal, S.; Waterworth, S. C.; Nick, A.; Vogel, H.; Florez, L.; Kaltenpoth, M.; Kwan, J. C.

10.1101/2024.01.23.576914 — genomics — Posted on 2024-01-25

985 Systemic delivery of a splice-switching oligonucleotide heteroduplex corrects splicing in central nervous system and muscle in spinal muscular atrophy mice

Halloy, F.; Ahlskog, N.; Wood, M.

10.1101/2024.01.24.577012 — molecular biology — Posted on 2024-01-25

986 Active prokaryotic and eukaryotic viral ecology across spatial scale in a deep-sea brine pool

Minch, B.; Chakraborty, M.; Purkis, S.; Rodrigue, M.; Moniruzzaman, M.

10.1101/2024.01.25.577265 — microbiology — Posted on 2024-01-25

987 Methods to study xenografted human cancer in genetically diverse mice

Hasham, M. G.; Sargent, J. K.; Warner, M. A.; Farley, S. R.; Hoffmann, B. R.; Stodola, T. J.; Brunton, C. J.; Munger, S. C.

10.1101/2024.01.23.576906 — cancer biology — Posted on 2024-01-25

988 CDK-4 regulates nucleolar size and anabolic metabolism as a fitness tradeoff in C. elegans

Webster, R. L.; Quintana, M.; Kafri, R.; Derry, B.

10.1101/2024.01.25.577258 — cell biology — Posted on 2024-01-25

989 Functional benefit of CRISPR/Cas9-induced allele deletion for RYR1 dominant mutation

Beaufils, M.; Melka, M.; Brocard, J.; Benoit, C.; Debbah, N.; Mamchaoui, K.; Romero, N. B.; Dalmas-Laurent, A. F.; Quijano-Roy, S.; Faure, j.; Rendu, j.; Marty, I.

10.1101/2024.01.24.576997 — neuroscience — Posted on 2024-01-25

990 Dynamic minimization of proteome reallocation explains metabolic transition in hierarchical utilization of mixed carbon sources

Liu, Z.; Chen, M.; Hu, J.; Wang, Y.; Chen, Y.

10.1101/2024.01.23.576957 — systems biology — Posted on 2024-01-25

991 Single NV in nanodiamond for quantum sensing of protein dynamics in an ABEL trap

Perez, I.; Krueger, A.; Wrachtrup, J.; Jelezko, F.; Boersch, M.

10.1101/2024.01.23.576955 — biophysics — Posted on 2024-01-25

992 The translocation activity of Rad54 reduces crossover outcomes during homologous recombination

Sridalla, K.; Woodhouse, M. V.; Hu, J.; Scheer, J.; Ferlez, B.; Crickard, J. B.

10.1101/2024.01.25.577253 — biochemistry — Posted on 2024-01-25

993 Regulatory genome annotation of 33 insect species

Asma, H.; Tieke, E.; Deem, K. D.; Rahmat, J.; Dong, T.; Huang, X.; Tomoyasu, Y.; Halfon, M. S.

10.1101/2024.01.23.576926 — genomics — Posted on 2024-01-25

994 Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle

Gurriaran-Rodriguez, U.; Kodippili, K.; Datzkiw, D.; Javandoost, E.; Xiao, F.; Rejas, M. T.; Rudnicki, M. A.

10.1101/2024.01.24.577041 — genetics — Posted on 2024-01-25

995 Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity

Anzell, A. R.; Kunz, A. B.; Donovan, J. P.; Tran, T. G.; Lu, X.; Young, S.; Roman, B. L.

10.1101/2024.01.25.576046 — developmental biology — Posted on 2024-01-25

996 Rbpms2 promotes female fate upstream of the nutrient sensing Gator2 complex component, Mios

Wilson, M. L.; Romano, S. N.; Khatri, N.; Aharon, D.; Liu, Y.; Kaufman, O. H.; Draper, B. W.; Marlow, F.

10.1101/2024.01.25.577235 — developmental biology — Posted on 2024-01-25

997 The effects of Paternal Radiofrequency Radiation Exposure on Sperm and Testicular Integrity in F1-Male Swiss Albino Mice

Pandey, N.; Giri, S.

10.1101/2024.01.23.576880 — cell biology — Posted on 2024-01-25

998 SPOT-RASTR - a cryo-EM specimen preparation technique that overcomes problems with preferred orientation and the air/water interface

ghazi esfahani, b.; Randolph, P. S.; peng, r.; Grant, T.; Stroupe, M. E.; Stagg, S.

10.1101/2024.01.24.577038 — molecular biology — Posted on 2024-01-25

999 Elucidating the effect of cations on Klebsiella pneumoniae biofilm and related genes

Ramakrishnan, J.; Murugavel, A.; Gunasekaran, S.

10.1101/2024.01.24.577145 — microbiology — Posted on 2024-01-25

1000 Broadly inhibitory antibodies against severe malaria virulence proteins

Reyes, R. A.; Raghavan, S. S. R.; Hurlburt, N. K.; Introini, V.; Kana, I. H.; Jensen, R. W.; Martinez-Scholze, E.; Gestal-Mato, M.; Bau, C. B.; Fernandez-Quintero, M. L.; Loeffler, J. R.; Ferguson, J. A.; Lee, W.-H.; Martin, G. M.; Theander, T. G.; Ssewanyana, I.; Feeney, M. E.; Greenhouse, B.; Bol, S.; Ward, A. B.; Bernabeu, M.; Pancera, M.; Turner, L.; Bunnik, E. M.; Lavstsen, T.

10.1101/2024.01.25.577124 — immunology — Posted on 2024-01-25

1001 Brief and diverse excitotoxic insults cause an increase in neuronal nuclear membrane permeability in the neonatal brain

Suryavanshi, P.; Langton, R.; Fairhead, K.; Glykys, J.

10.1101/2023.08.22.554167 — neuroscience — Posted on 2024-01-25

1002 Volume Electron Microscopy Reveals Unique Laminar Synaptic Characteristics in the Human Entorhinal Cortex

Plaza-Alonso, S.; Cano-Astorga, N.; DeFelipe, J.; Alonso-Nanclares, L.

10.1101/2023.11.20.567821 — neuroscience — Posted on 2024-01-25

1003 Joint signatures of morphological and microstructural inter-individual variation in the Alzheimer's spectrum

Bussy, A.; Patel, R.; Parent, O.; Salaciak, A.; Bedford, S. A.; Farzin, S.; Tullo, S.; Picard, C.; Villeneuve, S.; Poirier, J. A.; Breitner, J. C.; Devenyi, G. A.; PREVENT-AD Research Group, ; Tardif, C. L.; Chakravarty, M. M.

10.1101/2024.01.24.576996 — neuroscience — Posted on 2024-01-25

1004 Elucidation of chalkophomycin biosynthesis reveals N-hydroxypyrrole-forming enzymes

Crooke, A. M.; Chand, A. K.; Balskus, E. P.

10.1101/2024.01.24.577118 — biochemistry — Posted on 2024-01-25

1005 Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly

Monistrol, J.; Beton, J. G.; Johnston, E. C.; Saibil, H.

10.1101/2024.01.25.577078 — biochemistry — Posted on 2024-01-25

1006 scMeFormer: a transformer-based deep learning model for imputing DNA methylation states in single cells enhances the detection of epigenetic alterations in schizophrenia

Zhou, J.; Luo, C.; Liu, H.; Heffel, M. G.; Straub, R.; Kleinman, J.; Hyde, T.; Ecker, J. R.; Weinberger, D.; Han, S.

10.1101/2024.01.25.577200 — genomics — Posted on 2024-01-25

1007 Generation and characterization of CRISPR-Cas9-Mediated XPC Gene Knockout in Human Skin Cells

Nasrallah, A.; Rezvani, H.-R.; Kobaisi, F.; Hammoud, A.; Rambert, J.; Smits, J. P. H.; Sulpice, E.; Rachidi, W.

10.1101/2024.01.25.577199 — genetics — Posted on 2024-01-25

1008 Declining reservoir elevations following a two-decade drought increase water temperatures and non-native fish passage facilitating a downstream invasion

Eppehimer, D. E.; Yackulic, C. B.; Bruckerhoff, L. A.; Wang, J.; Young, K. L.; Bestgen, K. R.; Mihalevich, B. A.; Schmidt, J. C.

10.1101/2024.01.23.576966 — ecology — Posted on 2024-01-25

1009 The dilemma of underestimating freshwater biodiversity: morphological and molecular approaches

Schoenle, A.; Scepanski, D.; Floss, A.; Buechel, P.; Koblitz, A.-K.; Scherwass, A.; Arndt, H.; Waldvogel, A.-M.

10.1101/2024.01.23.576836 — ecology — Posted on 2024-01-25

1010 MRCK-1 activates non-muscle myosin for outgrowth of a unicellular tube in Caenorhabditis elegans

Popiel, E. M.; Derry, W. B.

10.1101/2024.01.25.577256 — developmental biology — Posted on 2024-01-25

1011 Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy

Renaud, C.; Alves Nicolau, C.; Maghe, C.; Trillet, K.; Jardine, J.; Escot, S.; David, N. B.; Gavard, J.; Bidere, N.

10.1101/2023.05.05.539527 — cell biology — Posted on 2024-01-25

1012 Med12 cooperates with multiple differentiation signals to enhance embryonic stem cell plasticity

Fernkorn, M.; Schröter, C.

10.1101/2024.01.22.576603 — cell biology — Posted on 2024-01-25

1013 Anti-gene oligonucleotides targeting Friedreichs ataxia expanded GAA:TTC repeats increase Frataxin expression

Mozafari, N.; Milagres, S. I. M.; Rocha, C. S. J.; Vargiu, C. M.; Freyberger, F.; Saher, O.; Umek, T.; Blomberg, P.; Jorgensen, P. T.; Smith, E. C. I.; Wengel, J.; Zain, R. L.

10.1101/2024.01.25.577034 — molecular biology — Posted on 2024-01-25

1014 Zebrafish carbohydrate sulfotransferase 6 (chst6) mutants provide a preclinical model for macular corneal dystrophy

Ersoz Gulseven, E.; Basol, M.; Ozaktas, H.; Kalyoncu, S.; Utine, C. A.; Cakan-Akdogan, G.

10.1101/2024.01.24.577150 — molecular biology — Posted on 2024-01-25

1015 Identification of sex-biased miRNA markers informative of heat-past events

van Gelderen, T. A.; Montfort, J.; Alvarez-Dios, J. A.; Piferrer, F.; Bobe, J.; Ribas, L.

10.1101/2024.01.24.577069 — molecular biology — Posted on 2024-01-25

1016 The diverse viromes of Australian lizards are shaped by host taxonomy and habitat

Mahar, J. E.; Wille, M.; Harvey, E.; Moritz, C.; Holmes, E. C.

10.1101/2024.01.24.577151 — microbiology — Posted on 2024-01-25

1017 A method for separating bacterial cultures into single cells and defined size fractions of biofilm aggregates

Nielsen, R. L.; Bjarnsholt, T.; Jakobsen, T. H.; Lichtenberg, M.

10.1101/2024.01.25.577188 — microbiology — Posted on 2024-01-25

1018 Coupled metalipidomics-metagenomics reveal structurally diverse sphingolipids produced by a wide variety of marine bacteria

Ding, S.; von Meijenfeldt, F. A. B.; Bale, N. J.; Damste, J. S. S.; Villanueva, L.

10.1101/2024.01.25.577268 — microbiology — Posted on 2024-01-25

1019 Oviposition status and sugar availability influence measures of transmission potential in malaria-infected mosquitoes.

Shiau, J. C.; Garcia-Diaz, N.; Kyle, D. E.; Pathak, A.

10.1101/2024.01.25.577126 — microbiology — Posted on 2024-01-25

1020 Erythrocyte TLR9 is upregulated in metabolic associated fatty liver disease, and is linked to an inflammatory immunometabolic signature.

Papadopoulos, C.; Mimidis, K.; Tentes, I.; Anagnostopoulos, K.

10.1101/2024.01.23.576889 — immunology — Posted on 2024-01-25

1021 First-in-class Transactivator-Free, Doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B-cell lymphomas

Justicia-Lirio, P. L.; Tristan-Manzano, M.; Maldonado-Perez, N.; Barbero-Jimenez, C.; Cortijo-Gutierrez, M.; Pavlovic, K.; Molina-Estevez, F. J.; Munoz, P.; Hinckley-Boned, A.; Grinan-Lison, C.; Navarro-Marchal, S. A.; Munoz-Ballester, J.; Gonzalez-Sierra, P. A.; Herrera, C.; Marchal, J. A.; Martin, F.

10.1101/2024.01.23.576842 — immunology — Posted on 2024-01-25

1022 Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-κB p50-IκBζ pathway

Daly, A.; Yeh, G.; Soltero, S.; Smale, S. T.

10.1101/2024.01.23.576959 — immunology — Posted on 2024-01-25

1023 A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo

Hanes, C. M.; Mah, K. M.; Steffen, D. M.; Marcucci, C. G.; Fuller, L. C.; Burgess, R. W.; Garrett, A. M.; Weiner, J. A.

10.1101/2024.01.25.577214 — neuroscience — Posted on 2024-01-25

1024 Neuroinflammation underlies the development of social stress induced cognitive deficit in sickle cell disease.

DeVeaux, S. A.; Vyshnya, S.; Propsom, K.; Gbotosho, O. T.; Singh, A. S.; Horning, R. Z.; Sharma, M.; Jegga, A. G.; Niu, L.; Botchwey, E. A.; Hyacinth, H. I.

10.1101/2024.01.24.577074 — neuroscience — Posted on 2024-01-25

1025 Acquiring musculoskeletal skills with curriculum-based reinforcement learning

Chiappa, A. S.; Tano, P.; Patel, N.; Ingster, A.; Pouget, A.; Mathis, A.

10.1101/2024.01.24.577123 — neuroscience — Posted on 2024-01-25

1026 Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

Carling, G. K.; Fan, L.; Foxe, N. R.; Norman, K.; Ye, P.; Wong, M. Y.; Zhu, D.; Yu, F.; Xu, J.; Yarahmady, A.; Chen, H.; Huang, Y.; Amin, S.; Zacharioudakis, E.; Chen, X.; Holtzman, D. M.; Mok, S.-A. K.; Gavathiotis, E.; Sinha, S. C.; Cheng, F.; Luo, W.; Gong, S.; Gan, L.

10.1101/2024.01.24.577107 — neuroscience — Posted on 2024-01-25

1027 High-speed two-photon microscopy with adaptive line-excitation

Li, Y.; Guo, S.; Mattison, B.; Yang, W.

10.1101/2024.01.24.577149 — neuroscience — Posted on 2024-01-25

1028 Electrically silent KvS subunits associate with native Kv2 channels in brain and impact diverse properties of channel function

Ferns, M.; van der List, D.; Vierra, N. C.; Lacey, T.; Murray, K. D.; Kirmiz, M.; Stewart, R. G.; Sack, J. T.; Trimmer, J. S.

10.1101/2024.01.25.577135 — neuroscience — Posted on 2024-01-25

1029 A new mRNA structure prediction based approach to identifying improved signal peptides for bone morphogenetic protein 2

Wilkinson, P.; Jackson, B.; Fermor, H.; Davies, R. P. W.

10.1101/2024.01.24.576995 — synthetic biology — Posted on 2024-01-25

1030 Self-adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Zou, Z.-P.; Wang, X.-G.; Sun, S.-T.; Mi, J.; Zhang, X.-P.; Yin, B.-C.; Zhou, Y.; Ye, B.-C.

10.1101/2024.01.25.577176 — synthetic biology — Posted on 2024-01-25

1031 Optimisation of surfactin yield in Bacillus using active learning and high-throughput mass spectrometry

Albornoz, R. G. V.; Oyarzun, D.; Burgess, K.

10.1101/2024.01.24.576661 — synthetic biology — Posted on 2024-01-25

1032 Neural space-time model for dynamic scene recovery in multi-shot computational imaging systems

Cao, R.; Divekar, N. S.; Nunez, J.; Upadhyayula, S.; Waller, L.

10.1101/2024.01.16.575950 — biophysics — Posted on 2024-01-25

1033 Structural Flexibility and Disassembly Kinetics of Single Ferritins using Optical Nanotweezers

Yousefi, A.; Zheng, Z.; Zargarbashi, S.; Assadipapari, M.; Hickman, G. J.; Parmenter, C. D. J.; Bueno-Alejo, C. J.; Sanderson, G.; Craske, D.; Xu, L.; Rahmani, M.; Ying, C.

10.1101/2023.09.22.558948 — biophysics — Posted on 2024-01-25

1034 Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)

Deganutti, G.; Pipito, L.; Rujan, R. M.; Weizmann, T.; Griffin, P.; Ciancetta, A.; Moro, S.; Reynolds, C. A.

10.1101/2022.10.26.513870 — bioinformatics — Posted on 2024-01-25

1035 Intrinsic-Dimension analysis for guiding dimensionality reduction and data fusion in multi-omics data processing

Gliozzo, J.; Guarino, V.; Bonometti, A.; Cabri, A.; Cavalleri, E.; Soto Gomez, M.; Reese, J.; Robinson, P. N.; Mesiti, M.; Valentini, G.; Casiraghi, E.

10.1101/2024.01.23.576822 — bioinformatics — Posted on 2024-01-25

1036 Self-Supervised Learning Improves Accuracy and Data Efficiency for IMU-Based Ground Reaction Force Estimation

Tan, T.; Shull, P.; Hicks, J.; Uhlrich, S.; Chaudhari, A.

10.1101/2023.10.25.564057 — bioengineering — Posted on 2024-01-25

1037 Metabolomic Profiles and Pathways in Osteoarthritic Human Cartilage: A Comparative Analysis with Healthy Cartilage

Welhaven, H. D.; Welfley, A. H.; Brahmachary, P.; Bergstrom, A.; Houske, E.; Glimm, M.; Bothner, B.; Hahn, A.; June, R. K.

10.1101/2024.01.25.577269 — biochemistry — Posted on 2024-01-25

1038 Diverse Database and Machine Learning Model to narrow the generalization gap in RNA structure prediction

Rouskn, S.; de Lajarte, A.; Martin Des Taillades, Y.; Kalicki, C.; Fuchs, F.; Aruda, J.; Salazar, D.; Allan, M.; LEsperance-Kerckhoff, C.; Kashi, A.; Jossinet, F.

10.1101/2024.01.24.577093 — biochemistry — Posted on 2024-01-25

1039 A small molecule VHL molecular glue degrader for cysteine dioxygenase 1

Tutter, A.; Buckley, D.; Golosov, A. A.; Ma, X.; Shu, W.; Mckay, D. J.; Darsigny, V.; Dovala, D.; Beckwith, R.; Solomon, J.; Rao, P.; Xu, L.; Fazal, A.; Lingel, A.; Wartchow, C.; Cobb, J. S.; Hachey, A.; Tullai, J.; Michaud, G. A.

10.1101/2024.01.25.576086 — biochemistry — Posted on 2024-01-25

1040 IntelliR: A comprehensive and standardized pipeline for automated profiling of higher cognition in mice

Daguano Gastaldi, V.; Hindermann, M.; Wilke, J. B.; Ronnenberg, A.; Arinrad, S.; Kraus, S.; Wildenburg, A.-F.; Ntolkeras, A.; Provost, M. J.; Ye, L.; Curto, Y.; Cortes-Silva, J.-A.; Butt, U. J.; Nave, K.-A.; Woznica Miskowiak, K.; Ehrenreich, H.

10.1101/2024.01.25.577156 — animal behavior and cognition — Posted on 2024-01-25

1041 Early acting inbreeding depression can evolve as an inbreeding avoidance mechanism

Brandvain, Y. J.; Thomson, L.; Pyhajarvi, T.

10.1101/2023.03.20.533524 — evolutionary biology — Posted on 2024-01-25

1042 Leucaena and Acaia leaf litter negatively affect the survivorship of tadpoles of the South Asian frog Microhyla ornata

Pathak-Broome, A.; Gour-Broome, V.; Mukherjee, S.

10.1101/2024.01.22.576772 — ecology — Posted on 2024-01-25

1043 VEGF counteracts shear stress-determined arterial fate specification during capillary remodeling.

Chen, D.; Rukhlenko, O. S.; Coon, B. G.; Joshi, D.; Chakraborty, R.; Martin, K. A.; Kholodenko, B. N.; Schwartz, M. A.; Simons, M.

10.1101/2024.01.23.576920 — developmental biology — Posted on 2024-01-25

1044 Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2

He, J.; Blazeski, A.; Nilanthi, U.; Menendez, J.; Pirani, S. C.; Levic, D. S.; Bagnat, M.; Singh, M. K.; Raya, J. G.; Garcia-Cardena, G.; Torres-Vazquez, J.

10.1101/2024.01.24.576555 — developmental biology — Posted on 2024-01-25

1045 High-parametric protein maps reveal the spatial organization in early-developing human lung

Sariyar, S.; Sountoulidis, A.; Hansen, J. N.; Salas, S. M.; Mardamshina, M.; Martinez Sacals, A.; Ballllosera Navarro, F.; Andrusivova, Z.; Li, X.; Czarnewski, P.; Lundeberg, J.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Samakovlis, C.; Lundberg, E.; Ayoglu, B.

10.1101/2024.01.25.577163 — developmental biology — Posted on 2024-01-25

1046 Occurrence of non-apical mitoses at the primitive streak, induced by relaxation of actomyosin and acceleration of the cell cycle, contributes to cell delamination during mouse gastrulation.

Despin-Guitard, E.; Plunder, S.; Mathiah, N.; THEVENEAU, E.; Migeotte, I.

10.1101/2024.01.24.577096 — developmental biology — Posted on 2024-01-25

1047 Rat anterior cingulate neurons responsive to rule or strategy changes are modulated by the hippocampal theta rhythm and sharp-wave ripples

Khamassi, M.; Peyrache, A.; Benchenane, K.; Hopkins, D.; Lebas, N.; Douchamps, V.; Droulez, J.; Battaglia, F. P.; Wiener, S. I.

10.1101/2024.01.24.577008 — neuroscience — Posted on 2024-01-25

1048 The Increasing Authorship trend in Neuroscience: A scientometric analysis across 11 countries

Paul, A.; Segreti, M.; Pani, P.; Brunamonti, E.; Genovesio, A.

10.1101/2024.01.24.577031 — neuroscience — Posted on 2024-01-25

1049 Grasp context-dependent uncertainty alters the relative contribution of anticipatory and feedback-based mechanisms in object manipulation

Dutta, S.; SKM, V.

10.1101/2024.01.24.577057 — neuroscience — Posted on 2024-01-25

1050 Automating clinical assessments of memory deficits: Deep Learning based scoring of the Rey-Osterrieth Complex Figure

Langer, N.; Weber, M.; Hebling Vieira, B.; Strzelczyk, D.; Wolf, L.; Pedroni, A.; Heitz, J.; Schultheis, C.; Troendle, M.; Arango Lasprilla, J. C.; Rivera, D.; Scarpina, F.; Zhao, Q.; Leuthold, R.; Wehrle, F.; Jenni, O. G.; Brugger, P.; Zaehle, T.; Lorenz, R.; Zhang, C.

10.1101/2022.06.15.496291 — neuroscience — Posted on 2024-01-25

1051 The voltage-gated potassium channel Shal (Kv4) contributes to active hearing in Drosophila

Gregory, E. S.; Xu, Y. Y. J.; Lee, T.-T.; Joiner, M.-l. A.; Kamikouchi, A.; Su, M. P.; Eberl, D. F.

10.1101/2024.01.24.577143 — neuroscience — Posted on 2024-01-25

1052 m6A-dependent circular RNA formation mediatestau-induced neurotoxicity

Frost, B.; Atrian, F.; Ramirez, P.; De Mange, J.; Marquez, M.; Gonzalez, E. M.; Minaya, M.; Karch, C.

10.1101/2024.01.25.577211 — neuroscience — Posted on 2024-01-25

1053 Ultrahigh Resolution Mass Spectrometry Imaging Maps Brain Lipidome Alterations Associated with Mild Traumatic Brain Injury

Leontyev, D.; Pulliam, A. N.; Ma, X.; Gaul, D. A.; LaPlaca, M. C.; Fernandez, F. M.

10.1101/2024.01.25.577203 — neuroscience — Posted on 2024-01-25

1054 A microglia clonal inflammatory disorder in Alzheimer's Disease

Vicario, R.; Fragkogianni, S.; Weber, L.; Lazarov, T.; Hu, Y.; Hayashi, S. Y.; Craddock, B. P.; Socci, N. D.; Alberdi, A.; Baako, A.; Ay, O.; Ogishi, M.; Lopez-Rodrigo, E.; Kappagantula, R.; Viale, A.; Iacobuzio-Donahue, C. A.; Zhou, T.; Ransohoff, R. M.; Chesworth, R.; Netherlands Brain Bank, ; Abdel-Wahab, O.; Boisson, B.; Elemento, O.; Casanova, J.-L.; Miller, W. T.; Geissmann, F.

10.1101/2024.01.25.577216 — neuroscience — Posted on 2024-01-25

1055 TRESK background potassium channel in MrgprA3+ pruriceptors regulates acute and chronic itch.

Llimos-Aubach, J.; Andres-Bilbe, A.; Pujol-Coma, A.; Pallas, I.; de Anta, J. M.; Soler, C.; Comes, N.; Callejo, G.; Gasull, X.

10.1101/2024.01.25.577205 — neuroscience — Posted on 2024-01-25

1056 Dual effects of ARX poly-alanine mutations in human cortical and interneuron development

Nieto-Estevez, V.; Varma, P.; Mirsadeghi, S.; Caballero, J.; Gamero-Alameda, S.; Hosseini, A.; Goswami, S.; Silvosa, M. J.; Thodeson, D. M.; Lybrand, Z. R.; Giugliano, M.; Navara, C.; Hsieh, J.

10.1101/2024.01.25.577271 — neuroscience — Posted on 2024-01-25

1057 Phylogenetic and biogeographic history of the Snooks (Centropomidae: Carangiformes) spanning the closure of the Isthmus of Panama

Ossa-Hernandez, N.; Ballen, G. A.; Acero P., A.; Tavera, J.

10.1101/2024.01.22.576679 — zoology — Posted on 2024-01-25

1058 Experts fail to reliably detect AI-generated histological data

Hartung, J.; Reuter, S.; Kulow, V. A.; Fahling, M.; Spreckelsen, C.; Mrowka, R.

10.1101/2024.01.23.576647 — scientific communication and education — Posted on 2024-01-25

1059 YamOmics: A comprehensive data resource on yam multi-omics

ding, l. j.; Wang, M.; Zhao, Y.; Shen, D.; Yang, Q.; Yang, T.; Yin, J.; He, L.; Dou, D.

10.1101/2024.01.23.576833 — plant biology — Posted on 2024-01-25

1060 Drosophila Undigested Metabolite Profiling reveals age related loss of intestinal amino acid transport regulates longevity

Mornement, A. A.; Dack, R. E.; Doupe, D. P.; Clark, R. I.

10.1101/2023.10.26.564159 — physiology — Posted on 2024-01-25

1061 LRG1 promotes atherosclerosis by activating macrophages

Wang, J.; Zhang, S.; Wang, J.; Zhong, J.; Liu, H.; Li, W.; Chen, M.; Xu, L.; Zhang, W.; Zhang, Z.; Wei, Z.; Guo, J.; Wang, X.; Sui, J.; Liu, X.; Wang, X.

10.1101/2024.01.23.576507 — pathology — Posted on 2024-01-25

1062 XKidneyOnco: An Explainable Framework to Classify Renal Oncocytoma and Chromophobe Renal Cell Carcinoma with a Small Sample Size

Javaheri, T.; Yang, X.; Yerra, S.; Seidi, K.; Setayesh, T.; Zhang, G.; Chitkushev, L.; Salar, S. S.; Sayeeduddin, Z.; Zarrin-Khameh, N.; Gharib, M. H.; Castro, P.; Haeri, M.; Rawassizadeh, R.

10.1101/2024.01.23.576782 — pathology — Posted on 2024-01-25

1063 IDENTIFICATION OF KEY GENES ASSOCIATED WITH PCOS (POLYCYSTIC OVARIAN SYNDROME) AND ENDOMETRIAL/OVARIAN CANCER THROUGH BIOINFORMATICS

Raulo, K.; Qazi, S.

10.1101/2024.01.23.576969 — cancer biology — Posted on 2024-01-25

1064 The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

Bauer, K. C.; Trehan, R.; Ruf, B.; Myojin, Y.; Benmebarek, M.-R.; Ma, C.; Seifert, M.; Nur, A.; Qi, J.; Huang, P.; Soliman, M.; Green, B. L.; Wabitsch, S.; Springer, D.; Rodriguez-Matos, F. J.; Ghabra, S.; Gregory, S. N.; Matta, J.; Dawson, B.; Golino, J.; Xie, C.; Dzutsev, A. K.; Trinchieri, G.; Korangy, F.; Greten, T. F.

10.1101/2024.01.23.576951 — cancer biology — Posted on 2024-01-25

1065 Mechanosensitivity of an ABC Membrane Transporter Revealed by Single Molecule FRET and Activity Measurement

Damm, A.; Paik, S.-J.; Sadhu, R. K.; Di Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Levy, D.; Bassereau, P.

10.1101/2024.01.24.577054 — biophysics — Posted on 2024-01-25

1066 Bridging DNA contacts allow Dps from E. coli to condense DNA

Shahu, S.; Vtyurina, N.; Das, M.; Meyer, A. S.; Ganji, M.; Abbondanzieri, E.

10.1101/2024.01.22.576774 — biophysics — Posted on 2024-01-25

1067 Shear flow as a tool to distinguish microscopic activities of molecular machines in a chromatin loop

Kumar, S.; Padinhateeri, R.; Thakur, S.

10.1101/2024.01.23.576811 — biophysics — Posted on 2024-01-25

1068 Investigating Sensitivity, Specificity and Accuracy of Variant Calling Pipelines for Analyzing SARS-CoV-2 Data

Krishna, A.; Choi, J. S.

10.1101/2024.01.24.576385 — bioinformatics — Posted on 2024-01-25

1069 Linking phenotypic and genotypic variation: a relaxed phylogenetic approach using the probabilistic programming language Stan

Gemmell, P.

10.1101/2024.01.23.576950 — bioinformatics — Posted on 2024-01-25

1070 CACIMAR: Cross-species Analysis of Cell Identities, Markers, Regulations and Interactions Using Single-cell RNA Sequencing Data

Jiang, J.; Li, J.; Xu, X.; Huang, S.; Jiang, F.; Liang, Y.; Wang, J.

10.1101/2024.01.23.576964 — bioinformatics — Posted on 2024-01-25

1071 Jointly benchmarking small and structural variant calls with vcfdist

Dunn, T.; Zook, J. M.; Holt, J. M.; Narayanasamy, S.

10.1101/2024.01.23.575922 — bioinformatics — Posted on 2024-01-25

1072 3D Simulation of Tissue Mechanics with Cell Polarization

Runser, S.; Vetter, R.; Iber, D.

10.1101/2023.03.28.534574 — bioinformatics — Posted on 2024-01-25

1073 Cross-modal Generation of Hit-like Molecules via Foundation Model Encoding of Gene Expression Signatures

Cheng, J.; Pan, X.; Yang, K.; Cao, S.; Liu, B.; Yuan, Y.; Yan, Q.

10.1101/2023.11.11.566725 — bioinformatics — Posted on 2024-01-25

1074 Tap Dancing Frogs: Posterior Toe Tapping and Feeding Behavior in Dendrobates tinctorius

Parrish, T. Q.; Fischer, E. K.

10.1101/2023.09.15.558032 — animal behavior and cognition — Posted on 2024-01-25

1075 Long-read de novo assembly of the red-legged partridge (Alectoris rufa) genome

Gonzalez-Prendes, R.; Pena, R. N.; Richart, C.; Nadal, J.; Ros-Freixedes, R.

10.1101/2024.01.23.576805 — genomics — Posted on 2024-01-25

1076 When the tap runs dry: The multi-tissue gene expression and physiological responses of water deprived Peromyscus eremicus

Blumstein, D.; MacManes, M.

10.1101/2024.01.22.576658 — genomics — Posted on 2024-01-25

1077 Reduced hybrid survival in a migratory divide between songbirds

Blain, S. A.; Justen, H.; Easton, W.; Delmore, K.

10.1101/2024.01.23.576948 — evolutionary biology — Posted on 2024-01-25

1078 Coarse-Grained Model of Serial Dilution Dynamics in Synthetic Human Gut Microbiome

Mahajan, T.; Maslov, S.

10.1101/2024.01.23.576928 — ecology — Posted on 2024-01-25

1079 Use of linear features by red-legged partridges in an intensive agricultural landscape: implications for landscape management in farmland

Perrot, C.; Berceaux, A.; Noel, M.; Arroyo, B.; Bacon, L.

10.1101/2023.07.27.550774 — ecology — Posted on 2024-01-25

1080 Large ungulates will be present in most of Japan by 2050 owing to natural expansion and human population shrinkage

Morosawa, T.; Iijima, H.; Kawamoto, T.; Kanno, T.; Araki, R.; Oka, T.

10.1101/2024.01.23.576970 — ecology — Posted on 2024-01-25

1081 Ivermectin resistance in dung beetles exposed for multiple generations

Tokman, D. G.; Torres, A. A.; Baena-Diaz, F.; Bustos, C.; Martinez M, I.

10.1101/2023.05.08.539900 — ecology — Posted on 2024-01-25

1082 Ancient occupation by humans leads to missing bird diversity in otherwise natural habitats

Murray, A. H.; Frishkoff, L. O.

10.1101/2024.01.23.576512 — ecology — Posted on 2024-01-25

1083 The Lifeact-EGFP Quail: A New Avian Model for Studying Actin Dynamics In Vivo

Alvarez, Y. D.; van der Spuy, M.; Wang, J. X.; Noordstra, I.; Tan, S. Z.; Carroll, M.; Yap, A. S.; Serralbo, O.; White, M. D.

10.1101/2023.11.19.567639 — developmental biology — Posted on 2024-01-25

1084 TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport

Wu, H.; Wang, L. C.; Sow, B.; Leow, D.; Zhu, J.; Gallo, K.; Wilsbach, K.; Gupta, R.; Ostrow, L.; Yeo, C.; Sobota, R.; Li, R.

10.1101/2024.01.24.576891 — cell biology — Posted on 2024-01-25

1085 OSBP is a major determinant of Golgi phosphatidylinositol 4-phosphate homeostasis

Doyle, C. P.; Timple, L.; Hammond, G. R.

10.1101/2023.12.21.572879 — cell biology — Posted on 2024-01-25

1086 BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue

Sieckmann, K.; Winnerling, N.; Silva Ribeiro, D. J.; Kardinal, R.; Steinheuer, L. M.; Schermann, G.; Klausen, C.; Blank-Stein, N.; Schulte-Schrepping, J.; Osei-Sarpong, C.; Becker, M.; Bonaguro, L.; Beyer, M.; Thurley, K.; May-Simera, H.; Zurkovic, J.; Thiele, C.; Ruiz de Almodovar, C.; Mass, E.; Wachten, D.

10.1101/2024.01.25.576526 — cell biology — Posted on 2024-01-25

1087 Interferon-γ as a Potential Inhibitor of SARS-CoV-2 ORF6 Accessory Protein

Krachmarova, E.; Petkov, P.; Lilkova, E.; Stoynova, D.; Malinova, K.; Hristova, R.; Gospodinov, A.; Ilieva, N.; Nacheva, G.; Litov, L.

10.1101/2024.01.24.577015 — molecular biology — Posted on 2024-01-25

1088 GABAergic synaptic scaling is triggered by changes in spiking activity rather than AMPA receptor activation

Gonzalez-Islas, C. E.; Sabra, Z.; Fong, M.-f.; Bulow, P.; Au Yong, N.; Engisch, K.; Wenner, P.

10.1101/2023.03.08.531789 — neuroscience — Posted on 2024-01-25

1089 Evaluating the effect of denoising submillimeter auditory fMRI data with NORDIC

Faes, L. K.; Lage-Castellanos, A.; Valente, G.; Yu, Z.; Cloos, M. A.; Vizioli, L.; Moeller, S.; Yacoub, E.; De Martino, F.

10.1101/2024.01.24.577070 — neuroscience — Posted on 2024-01-25

1090 The effect of semantic content on the perception of audiovisual movieclips

Kesoglou, A. M.; Mikellidou, K.

10.1101/2024.01.24.576956 — neuroscience — Posted on 2024-01-25

1091 Selective consistency of recurrent neural networks induced by plasticity as a mechanism of unsupervised perceptual learning

Goto, Y.; Kitajo, K.

10.1101/2023.06.30.547192 — neuroscience — Posted on 2024-01-25

1092 Astrocytes tune neuronal excitability through the calcium-activated potassium current sIAHP

Exposito, S.; Alberquilla, S.; Martin, E. D.

10.1101/2024.01.24.576973 — neuroscience — Posted on 2024-01-25

1093 Dose range-finding toxicity study in rats with recombinant human lactoferrin produced in Komagataella phaffii

Peterson, R.; Crawford, R. B.; Blevins, L. K.; Kaminski, N. E.; Sass, J. S.; Ferraro, B.; Vishwanath-Deutsch, R.; Clark, A. J.; Malinczak, C.-A.

10.1101/2024.01.22.576753 — pharmacology and toxicology — Posted on 2024-01-25

1094 Self-amplifying ROS-sensitive SN38 Dimeric Prodrug nanoparticles for Combined Chemotherapy and Ferroptosis in Cancer Treatment

Qin, Y.; Wang, F.; Gao, Z.; Tian, C.; Kamei, K.-i.

10.1101/2024.01.22.576778 — cancer biology — Posted on 2024-01-25

1095 3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression

Mortenson, K. L.; Dawes, C.; Wilson, E. R.; Patchen, N.; Johnson, H. E.; Gertz, J.; Bailey, S. D.; Liu, Y.; Varley, K. E.; Zhang, X.

10.1101/2024.01.23.576965 — cancer biology — Posted on 2024-01-25

1096 Polymer-solubilized structure of the mechanosensitive channel MscS suggests the role of protein-lipid interactions in the functional gating cycle

Moller, E.; Britt, M.; Zhou, F.; Yang, H.; Ernst, R. K.; Sukharev, S. I.; Matthies, D.

10.1101/2024.01.22.576751 — biophysics — Posted on 2024-01-25

1097 Recurrent Neural Network-based Prediction of O-GlcNAcylation Sites in Mammalian Proteins

Seber, P.; Braatz, R. D.

10.1101/2023.08.24.554563 — bioinformatics — Posted on 2024-01-25

1098 A study on experimental bias in post-translational modification predictors

Zuallaert, J.; Ramasamy, P.; Bouwmeester, R.; Callewaert, N.; Degroeve, S.

10.1101/2022.11.28.518163 — bioinformatics — Posted on 2024-01-25

1099 Minimal-invasive 3D laser printing of microimplants in organismo

Afting, C.; Mainik, P.; Vazquez-Martel, C.; Abele, T.; Kaul, V.; Goepfrich, K.; Lemke, S.; Blasco, E.; Wittbrodt, J.

10.1101/2024.01.23.576808 — bioengineering — Posted on 2024-01-25

1100 PPTC7 limits mitophagy through proximal and dynamic interactions with BNIP3 and NIX

Wei, L.; Gok, M. O.; Svoboda, J. D.; Forny, M.; Friedman, J. R.; Niemi, N. M.

10.1101/2024.01.24.576953 — biochemistry — Posted on 2024-01-25

1101 Superior target genes and pathways for RNAi mediated pest control revealed by genome wide analysis in the red flour beetle Tribolium castaneum

Buer, B.; Donitz, J.; Milner, M.; Mehlhorn, S.; Hinners, C.; Siemanowski-Hrach, J.; Ulrich, J. C.; Grossmann, D.; Cedden, D.; Nauen, R.; Geibel, S.; Bucher, G.

10.1101/2024.01.24.577003 — genomics — Posted on 2024-01-25

1102 Implications of noncoding regulatory functions in the development of insulinomas

Ramos-Rodriguez, M.; Subirana-Granes, M.; Norris, R.; Sordi, V.; Fernandez Ruiz, A.; Berenguer Balaguer, C.; Fuentes-Paez, G.; Perez-Gonzalez, B.; Raurell-Vila, H.; Chowdhury, M.; Corripio, R.; Partelli, S.; Lopez-Bigas, N.; Pellegrini, S.; Montanya, E.; Nacher, M.; Falconi, M.; Layer, R.; Rovira, M.; Gonzalez-Perez, A.; Piemonti, L.; Pasquali, L.

10.1101/2024.01.23.576802 — genomics — Posted on 2024-01-25

1103 Epistasis facilitates functional evolution in an ancient transcription factor

Metzger, B. P.; Park, Y.; Starr, T. N.; Thornton, J. W.

10.1101/2023.04.19.537271 — evolutionary biology — Posted on 2024-01-25

1104 Gelatinous matrix, an original convergent evolution to cope with oligotrophy in Nassellaria (Radiolaria)

Llopis Monferrer, N.; Romac, S.; Laget, M.; Biard, T.; Sandin, M. M.

10.1101/2024.01.22.576765 — evolutionary biology — Posted on 2024-01-25

1105 Cross-species genomic survey reveals a single origin of the soft-shelled turtles

Li, W.; Zhu, J.; Chen, J.; Chen, C.; Zhu, X.

10.1101/2024.01.23.576798 — evolutionary biology — Posted on 2024-01-25

1106 Body size is a better predictor of intra- than interspecific variation of animal stoichiometry across realms

Nessel, M. P.; Dezerald, O.; Merder, J.; Andraczek, K.; Brose, U.; Filipiak, M.; Jackson, M.; Jochum, M.; Harpole, S.; Hillebrand, H.; Leroux, S. J.; Onstein, R.; Paseka, R.; Perry, G.; Rugenski, A.; Sitters, J.; Sperfeld, E.; Striebel, M.; Zandona, E.; Doi, H.; Eisenhauer, N.; Farjalla, V. F.; Gotelli, N. J.; Hood, J.; Kratina, P.; Moody, E. K.; Nash, L. N.; Potapov, A. M.; Romero, G. Q.; Roussel, J.-M.; Scheu, S.; Seeber, J.; Susanti, W. I.; Tiunov, A.; Gonzalez, A. L.

10.1101/2024.01.22.576743 — ecology — Posted on 2024-01-25

1107 Genetic network analysis uncovers spatial variation in diversity and connectivity of a species presenting a continuous distribution

Fournier, C.; Manseau, M.; Redquest, B.; Andrew, L.; Kelly, A.; Hervieux, D.; Hegel, T.; Pittoello, G.; Trim, V.; Brannen, D.; Wilson, P.

10.1101/2024.01.22.576731 — ecology — Posted on 2024-01-25

1108 Selection of different parameters to study epistatic effect between heat shock and slightly deleterious mutations in the most fragile stage of embryogenesis Cyprinus carpio L.

Kuzmin, A. V.; Skripskaya, V.; Lobanova, V.; Brodovaya, P.; Tarasova, A.; Mukhitov, M.; Popadin, K.; Mikhailova, A. G.; Vinogradov, E.; Mugue, N.; Balashov, D.

10.1101/2024.01.23.576732 — ecology — Posted on 2024-01-25

1109 Forest growth resistance and resilience to the 2018-2020 drought depend on tree diversity and mycorrhizal type

Sachsenmaier, L.; Schnabel, F.; Dietrich, P.; Eisenhauer, N.; Ferlian, O.; Quosh, J.; Richter, R.; Wirth, C.

10.1101/2024.01.23.576797 — ecology — Posted on 2024-01-25

1110 N-terminal signals in the SNX-BAR paralogs Vps5 and Vin1 guide coat complex formation

Shortill, S. P.; Frier, M. S.; Davey, M.; Conibear, E.

10.1101/2024.01.24.576755 — cell biology — Posted on 2024-01-25

1111 Redefining hematopoietic progenitor cells and reforming the hierarchy of hematopoiesis

Chen, L.; Sun, Q.; Li, G.; Huang, Q.; Chen, S.; Fu, Y.; Yue, Y.

10.1101/2023.01.27.524347 — cell biology — Posted on 2024-01-25

1112 Kinase inhibitor-induced cell-type specific vacuole formation in the absence of canonical ATG5-dependent autophagy

Jose, S.; Sharma, H.; Insan, J.; Sharma, K.; Arora, V.; Dhamija, S.; Eid, N.; Menon, M. B.

10.1101/2023.08.27.554994 — cell biology — Posted on 2024-01-25

1113 Sulfur cycle microbiota in extremely contaminated Technosol with ongoing pedogenesis: culture-dependent and metagenomic approach

Demin, K. A.; Minkina, T. M.; Sushkova, S.; Delegan, Y. A.; Kocharovskaya, Y.; Gorovtsov, A. V.

10.1101/2023.12.06.570440 — microbiology — Posted on 2024-01-25

1114 Opposing effects of acellular and whole cell pertussis vaccines on Bordetella pertussis biofilm formation, Siglec-F+ neutrophil recruitment and bacterial clearance in mouse nasal tissues

Hall, J. M.; Gutierrez-Ferman, J. L.; Shamseldin, M. M.; Guo, M. M.; Gupta, Y. A.; Deora, R.; Dubey, P.

10.1101/2024.01.23.576795 — immunology — Posted on 2024-01-25

1115 Maternal histone methyltransferases antagonistically regulate monoallelic expression in C. elegans

Sands, B.; Yun, S.; Oshima, J.; Mendenhall, A. R.

10.1101/2024.01.22.576748 — systems biology — Posted on 2024-01-25

1116 Citizen Science Data on Urban Forageable Plants: A Case Study in Brazil

Soares, F. M.; Pires, L. F.; Garcia, M. C.; Coradin, L.; Ghilardi-Lopes, N. P.; Silva, R. R.; Carvalho, A. M. d.; Gavai, A.; Bouzembrak, Y.; Maculan, B. C. M. d. S.; Koffler, S.; Montedo, U. B.; Drucker, D. P.; Santiago, R.; Carvalho, M. C. P. d.; Lima, A. C. d. S.; Gabriel, H. D. E.; Franca, S. G. M. d.; Almeida, K. R. d.; Santos, B. J. d.; Saraiva, A. M.

10.1101/2024.01.22.575882 — plant biology — Posted on 2024-01-25

1117 Polyploid genome assembly of Cardamine chenopodiifolia

Emonet, A.; Awad, M.; Tikhomirov, N.; Vasilarou, M.; Perez-Anton, M.; Gan, X.; Novikova, P. Y.; Hay, A.

10.1101/2024.01.24.576990 — plant biology — Posted on 2024-01-25

1118 Dietary super-doses of cholecalciferol fed to aged laying hens illustrates limitation of 24,25-dihydroxycholecalciferol conversion

Warren, M. F.; Pitman, P. M.; Hodgson, D. D.; Thompson, N. C.; Livingston, K. A.

10.1101/2021.10.14.464328 — physiology — Posted on 2024-01-25

1119 Morphine-induced side effects can be differentially modulated by cannabidiol in male and female rats.

Jesus, C. H. A.; Volpe, J.; Sotomaior, B. B.; Barbosa, M. A. R.; Ferreira, M. V.; Fiatcoski, F.; Genaro, K.; Crippa, J. A. d. S.; Souto, D. E. P.; da Cunha, J. M.

10.1101/2024.01.22.576721 — pharmacology and toxicology — Posted on 2024-01-25

1120 Mitochondrial uncoupler and retinoic acid synergistically induce differentiation and inhibit proliferation in neuroblastoma

Jiang, H.; Tiche, S. J.; He, C. J.; Jedoui, M.; Forgo, B.; Zhao, M.; He, B.; Li, Y.; li, A. M.; Truong, A. T.; Ho, J.; Simmermaker, C.; Yang, Y.; Zhou, M.-N.; Zhen, H.; Cuthbertson, D. J.; Svensson, K. J.; Hazard, F. K.; Shimada, H.; Chiu, B.; Ye, J.

10.1101/2024.01.22.576741 — cancer biology — Posted on 2024-01-25

1121 The inherent fragility of collective proliferative control

Caldwell, M. G.; Lander, A. D.

10.1101/2024.01.23.576783 — cancer biology — Posted on 2024-01-25

1122 Transport Cocktails for Cancer Therapeutics

Kavousanakis, M.; Bhatavdekar, O.; Bastiaannet, R.; Kevrekidis, Y.; Sofou, S.

10.1101/2024.01.23.576806 — cancer biology — Posted on 2024-01-25

1123 Tumor Agnostic Drug Delivery with Self-Agglomerating Nanohydrogels (SANGs)

Housley, S. N.; Matyunina, L.; Lee, S.; Herrmann, O.; Arboleda, J.; McDonald, J. F.; Finn, M. G.

10.1101/2024.01.22.575714 — cancer biology — Posted on 2024-01-25

1124 Quantifying Unbiased Conformational Ensembles from Biased Simulations Using ShapeGMM

Sasmal, S.; Pal, T.; Hocky, G. M.; McCullagh, M.

10.1101/2024.01.22.576692 — biophysics — Posted on 2024-01-25

1125 Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region

Xu, J.; Esser, V.; Golebiowska-Mendroch, K.; Bolembach, A. A.; Rizo, J.

10.1101/2024.01.24.577102 — biophysics — Posted on 2024-01-25

1126 Cross-omic Transcription Factors meta-analysis: an insight on TFs accessibility and expression correlation

Martini, L.; Bardini, R.; Savino, A.; Di Carlo, S.

10.1101/2024.01.23.576789 — bioinformatics — Posted on 2024-01-25

1127 Mapping Cell-to-cell Interactions from Spatially Resolved Transcriptomics Data

Zhu, J. Z.; Wang, Y.; Chang, W. Y.; Malewska, A.; Napolitano, F.; Gahan, J. C.; Unni, N.; Zhao, M.; Wu, F.; Guo, L.; Zhao, Z.; Chen, D. Z.; Hannan, R.; Zhang, S.; Xiao, G.; Mu, P.; Hanker, A. B.; Strand, D.; Arteaga, C. L.; Desai, N.; Wang, X.; Xie, Y.; Wang, T.

10.1101/2023.09.18.558298 — bioinformatics — Posted on 2024-01-25

1128 Physiological and behavioural resistance of malaria vectors in rural West-Africa : a data mining study to address their fine-scale spatiotemporal heterogeneity, drivers, and predictability

Taconet, P.; SOMA, D. D.; Zogo, B.; Mouline, K.; Simard, F.; Koffi, A. A.; Dabire, R. K.; Pennetier, C.; Moiroux, N.

10.1101/2022.08.20.504631 — ecology — Posted on 2024-01-25

1129 Preconfigured cortico-thalamic neural dynamics constrain movement-associated thalamic activity

Gonzalez-Pereyra, P.; Martinez-Montalvo, M. G.; Ortega-Romero, D. I.; Perez-Diaz, C. I.; Merchant, H.; Tellez, L. A.; Rueda-Orozco, P. E.

10.1101/2023.09.20.558667 — neuroscience — Posted on 2024-01-25

1130 Measuring CO2 assimilation of Arabidopsis thaliana whole plants and seedlings

Brazel, A. J.; Turck, F.; O'Maoileidigh, D. S.

10.1101/2024.01.22.576682 — plant biology — Posted on 2024-01-25

1131 Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies

He, T.; Xiao, L.; Qiao, Y.; Klingbeil, O.; Young, E.; Wu, X. S.; Mannan, R.; Mahapatra, S.; Eyunni, S.; Tien, J. C.-Y.; Wang, X.; Zheng, Y.; Kim, N.; Zheng, H.; Hou, S.; Su, F.; Miner, S. J.; Mehra, R.; Cao, X.; Abbineni, C.; Samajdar, S.; Ramachandra, M.; Parolia, A.; Vakoc, C. R.; Chinnaiyan, A. M.

10.1101/2024.01.22.576669 — cancer biology — Posted on 2024-01-25

1132 Single-Cell Stress Analysis in Tumoroids.

Rodrigues de Mercado, R.; Beslmuller, K.; Vorselen, D.; Danen, E.; Schmidt, T.

10.1101/2024.01.22.576025 — biophysics — Posted on 2024-01-25

1133 On the lipid dependence of bacterial mechanosensitive channel gating in situ

Britt, M.; Sawasato, K.; Moller, E.; Kidd, G.; Bogdaov, M.; Sukharev, S. I.

10.1101/2024.01.22.576706 — biophysics — Posted on 2024-01-25

1134 In vitro neutrophil-bacteria assay in whole blood microenvironments with single-cell confinement

Li, C.; Hendrikse, N. W.; Argall-Knapp, Z.; Mai, M.; Kim, J. S.

10.1101/2024.01.22.576723 — biophysics — Posted on 2024-01-25

1135 The eyes have it: Inter-subject correlations of pupillary responses for audience response measurement in VR

Schmaelzle, R.; Wu, J.; Lim, S.; Bente, G.

10.1101/2024.01.22.576685 — physiology — Posted on 2024-01-25

1136 GeneSelectR: An R Package Workflow for Enhanced Feature Selection from RNA Sequencing Data

Zhakparov, D.; Moriarty, K.; Roqueiro, D.; Baerenfaller, K.

10.1101/2024.01.22.576646 — bioinformatics — Posted on 2024-01-25

1137 Heparan sulfate modified proteins affect cellular processes central to neurodegeneration and modulate presenilin function

Schultheis, N.; Connell, A.; Kapral, A.; Becker, R. J.; Mueller, R.; Shah, S.; O'Donnell, M.; Roseman, M.; Wang, W.; Yin, F.; Weiss, R.; Selleck, S. B.

10.1101/2024.01.23.576895 — neuroscience — Posted on 2024-01-25

1138 Constitutive sodium permeability in a C. elegans two-pore domain potassium channel

Andrini, O.; Ben Soussia, I.; Tardy, P.; Walker, D. S.; Pena-Varas, C.; Ramirez, D.; Gendrel, M.; Mercier, M.; El Mouridi, S.; Leclercq-Blondel, A.; Gonzalez, W.; Schafer, W. R.; Jospin, M.; Boulin, T.

10.1101/2024.01.22.576648 — physiology — Posted on 2024-01-25

1139 A Generalized Higher-order Correlation Analysis Framework for Multi-Omics Network Inference

Liu, W.; Pratte, K. A.; Castaldi, P.; Hersh, C.; Bowler, R. P.; Banaei-Kashani, F.; Kechris, K.

10.1101/2024.01.22.576667 — bioinformatics — Posted on 2024-01-25

1140 Activation of HIF2 leads to vascular remodeling and inflammation, coronary thrombosis and arterial dilation, recapitulating cardiac involvement of Kawasaki disease.

Escobar, B.; Menendez-Montes, I.; Albendea-Gomez, T.; Mendoza-Tamajon, S.; Castro-Mecinas, R.; Diaz-Diaz, C.; Palacios, B.; Ruiz-Cabello, J.; Jimenez-Borreguero, L. J.; Cid, M. C.; Takahashi, K.; Martin-Puig, S.

10.1101/2024.01.22.576642 — pathology — Posted on 2024-01-25

1141 Computational approach for decoding Malaria Drug Targets from Single-Cell Transcriptomics and finding potential drug molecule

choudhuri, s.; Ghosh, B.

10.1101/2024.01.22.576718 — bioinformatics — Posted on 2024-01-25

1142 A dual-gene reporter-amplifier architecture for enhancing the sensitivity of molecular MRI by water exchange

Huang, Y.; Chen, X.; Zhu, Z.; Mukherjee, A.

10.1101/2024.01.22.576672 — bioengineering — Posted on 2024-01-25

1143 Genetic characterisation of candidate ecdysteroid kinases in Drosophila melanogaster

Scanlan, J.; Robin, C.

10.1101/2024.01.22.576657 — genetics — Posted on 2024-01-25

1144 Exploring phenotypic diversity: a comparative analysis of cichlid convergence

Leal-Cardin, M.; Bracamonte, S. E.; Aldegunde, J.; Hudson, A. G.; Magalhaes, I. S.; Ornelas-Garcia, C. P.; Barluenga, M.

10.1101/2024.01.23.576830 — evolutionary biology — Posted on 2024-01-25

1145 Expression diversity of cichlid MHC alleles

Bracamonte, S. E.; Hablützel, P. I.; Lozano-Martin, C.; Barluenga, M.

10.1101/2024.01.23.576710 — evolutionary biology — Posted on 2024-01-25

1146 The ecological relevance of flagellar motility in soil bacterial communities

Ramoneda, J.; Fan, K.; Lucas, J. M.; Chu, H.; Bissett, A.; Strickland, M. S.; Fierer, N.

10.1101/2024.01.22.576697 — ecology — Posted on 2024-01-25

1147 TNFR2 blockade promotes anti-tumoral immune response in PDAC by targeting activated Treg and reducing T cell exhaustion

Debesset, A.; Pilon, C.; Meunier, S.; Bonizec, O.; Richer, W.; Thiolat, A.; Houppe, C.; Ponzo, M.; Magnan, J.; Caudana, P.; Tosello boari, J.; Baulande, S.; To, N. H.; Salomon, B. L.; Piaggio, E.; Cascone, I.; Cohen, J. L.

10.1101/2024.01.22.573571 — immunology — Posted on 2024-01-25

1148 BATMAN: Improved T cell receptor cross-reactivity prediction benchmarked on a comprehensive mutational scan database

Banerjee, A.; Pattinson, D. J.; Wincek, C. L.; Bunk, P.; Chapin, S. R.; Navlakha, S.; Meyer, H. V.

10.1101/2024.01.22.576714 — immunology — Posted on 2024-01-25

1149 Identifying new cancer genes based on the integration of annotated gene sets via hypergraph neural networks

Deng, C.; Li, H.; Zhang, L.; Liu, Y.; Li, Y.; Wang, J.

10.1101/2024.01.22.576645 — systems biology — Posted on 2024-01-25

1150 Inference of alveolar capillary network connectivity from blood flow dynamics

Schmid, K.; Olivares, A. L.; Camara, O.; Kuebler, W. M.; Ochs, M.; Hocke, A. C.; Fischer, S. C.

10.1101/2024.01.22.576641 — physiology — Posted on 2024-01-25

1151 GTDrift: A resource for exploring the interplay between genetic drift, genomic and transcriptomic characteristics in eukaryotes

Benitiere, F.; Necsulea, A.; Duret, L.

10.1101/2024.01.23.576799 — evolutionary biology — Posted on 2024-01-25

1152 Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis

Wang, F.; Liu, X.; Huang, F.; Zhou, Y.; Wang, X.; Song, Z.; Wang, S.; Wang, X.; Shi, D.; Ruan, G.; Ji, X.; Zhang, E.; Tan, Z.; Ye, Y.; Wang, C.; Zhu, J.; Wang, W.

10.1101/2023.06.02.543432 — microbiology — Posted on 2024-01-25

1153 ExoS Effector in Pseudomonas aeruginosa Hyperactive Type III Secretion System Mutant Promotes Enhanced Plasma Membrane Rupture in Neutrophils

Reuven, A. D.; Mwaura, B. M.; Bliska, J. B.

10.1101/2024.01.24.577040 — microbiology — Posted on 2024-01-25

1154 Unravelling the ancient fungal DNA from the Iceman's gut

Oskolkov, N.; Sandionigi, A.; Gotherstrom, A.; Canini, F.; Turchetti, B.; Zucconi, L.; Mimmo, T.; Buzzini, P.; Borruso, L.

10.1101/2024.01.24.576930 — microbiology — Posted on 2024-01-25

1155 The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota

Katsoulis-Dimitriou, S.; Nikouli, E.; Gkalogianni, E.-Z.; Karapanagiotidis, I.; Kormas, K.

10.1101/2024.01.24.576938 — microbiology — Posted on 2024-01-25

1156 Comparative genomics reveals intra and inter species variation in the pathogenic fungus Batrachochytrium dendrobatidis

Yacoub, M. N.; Stajich, J. E.

10.1101/2024.01.24.576925 — microbiology — Posted on 2024-01-25

1157 Thiosulfinate tolerance gene clusters are common features of Burkholderia onion pathogens.

Paudel, S.; Zhao, M.; Stice, S. P.; Dutta, B.; Kvitko, B. H.

10.1101/2024.01.24.577064 — microbiology — Posted on 2024-01-25

1158 Rapid, automatic typing of Clostridioides difficile Ribotypes Using MALDI-TOF MS

Sanchez-Blazquez, M.; Guerrero-Lopez, A.; Candela, A.; Belenguer-Llorens, A.; Moreno, J. M.; Sevilla Salcedo, C.; Sanchez-Cueto, M.; Arroyo, M. J.; Calama, N.; Martin, A.; Gomez-Verdejo, V.; Olmos, P. M.; Mancera, L.; Munoz, P.; Marin, M.; Alcala, L.; Rodriguez-Temporal, D.; Rodriguez Sanchez, B.

10.1101/2024.01.24.576988 — microbiology — Posted on 2024-01-25

1159 Harnessing the diversity of Burkholderia spp. prophages for therapeutic potential

Nordstrom, H. R.; Griffith, M. P.; Srinivasa, V. R.; Wallace, N. R.; Li, A.; Cooper, V. S.; Shields, R. K.; Van Tyne, D.

10.1101/2024.01.24.577087 — microbiology — Posted on 2024-01-25

1160 Extracellular ATP is a signalling molecule in bacteria

Tronnet, S.; Pandey, V.; Lloret-Berrocal, M.; Perez-del-Pozo, M.; Soderholm, N.; Hernandez-Ortego, C.; Billker, O.; Nordstrom, A.; Puhar, A.

10.1101/2024.01.24.577065 — microbiology — Posted on 2024-01-25

1161 Mechanistic basis of gene-specific transcription regulation by the Integrator complex

Sabath, K.; Nabih, A.; Arnold, C.; Moussa, R.; Domjan, D.; Zaugg, J. B.; Jonas, S.

10.1101/2024.01.24.576984 — molecular biology — Posted on 2024-01-25

1162 Dissociable neural signals for reward and emotion prediction errors

Heffner, J.; Frömer, R.; Nassar, M.; FeldmanHall, O.

10.1101/2024.01.24.577042 — neuroscience — Posted on 2024-01-25

1163 The control costs of human brain dynamics

Ceballos, E. G.; Luppi, A. I.; Castrillon, G.; Saggar, M.; Misic, B.; Riedl, V.

10.1101/2024.01.24.577068 — neuroscience — Posted on 2024-01-25

1164 Adaptation to complex environments reveals pervasive trade-offs and genomic targets with large pleiotropic effects

Rego, A.; Stajic, D.; Celorio-Mancera, M. d. l. P.; Stelkens, R.

10.1101/2024.01.24.577006 — evolutionary biology — Posted on 2024-01-25

1165 Development of a qPCR assay and a LAMP assay for Verticillium longisporum detection and a triplex qPCR assay for simultaneous detection of V. longisporum, Leptosphaeria biglobosa and L. maculans from canola samples

Fu, H.; Yang, Y.; Jiang, J.; Daniels, G.; Hill, B.; Xue, S.; Zahr, K.; Stellar, L.; Harding, M.; Feindel, D.; Bvindi, C.; Fernando, D.; Feng, J.

10.1101/2024.01.24.577072 — microbiology — Posted on 2024-01-24

1166 Pinpointing the microbiota of tardigrades: what is really there?

Surmacz, B.; Stec, D.; Prus-Frankowska, M.; Buczek, M.; Michalczyk, Łukasz; Łukasik, P.

10.1101/2024.01.24.577024 — microbiology — Posted on 2024-01-24

1167 Growth characterization and biostimulant potential of Coelastrella sp. D14 a greenmicroalga isolated from a solar panel.

Baldanta Callejo, S.; Ferreira, A.; Gouveia, L.; Navarro Llorens, J. M.; Guevara, G.

10.1101/2024.01.24.576708 — microbiology — Posted on 2024-01-24

1168 Cryopreservation of the collector urchin embryo, Tripneustes gratilla

Westbrook, C. E.; Daly, J.; Bowen, B.; Hagedorn, M.

10.1101/2024.01.22.576601 — zoology — Posted on 2024-01-24

1169 Novel sensor-integrated proteome on chip (SPOC) platform with thousands of folded proteins on a 1.5 sq-cm biosensor chip to enable high-throughput real-time label-free screening for kinetic analysis.

Agu, C. V.; Cook, R. L.; Martelly, W.; Gushgari, L. R.; Mohan, M.; Takulapalli, B. R.

10.1101/2024.01.23.575909 — systems biology — Posted on 2024-01-24

1170 Detecting adaptive changes in gene copy number distribution accompanying the human out-of-Africa expansion

Otto, M.; Zheng, Y.; Grablowitz, P.; Wiehe, T.

10.1101/2023.08.14.553171 — evolutionary biology — Posted on 2024-01-24

1171 BaYaka mothers balance childcare and subsistence tasks during collaborative foraging in Congo Basin

Visine, A. E. S.; Boyette, A. H.; Ouamba, Y. R.; Lew-Levy, S.; Sarma, M.; Jang, H.

10.1101/2024.01.22.576450 — ecology — Posted on 2024-01-24

1172 Differential Modulation of Polycomb-Associated Histone Marks by cBAF, pBAF, and gBAF Complexes

Bergwell, M.; Park, J.; Kirkland, J. G.

10.1101/2023.09.23.557848 — molecular biology — Posted on 2024-01-24

1173 Bacterial vampirism mediated through taxis to serum

Glenn, S. J.; Gentry-Lear, Z.; Shavlik, M.; Harms, M. J.; Asaki, T. J.; Baylink, A.

10.1101/2023.07.07.548164 — microbiology — Posted on 2024-01-24

1174 Automatic Geometry-based Estimation of the Locus Coeruleus Region on T1-Weighted Magnetic Resonance Images

Aganj, I.; Mora, J.; Fischl, B. R.; Augustinack, J. C.

10.1101/2024.01.23.576958 — neuroscience — Posted on 2024-01-24

1175 Instability of excitatory synapses in experimental autoimmune encephalomyelitis and the outcome for excitatory circuit inputs to individual cortical neurons

Gillani, R. L.; Kironde, E. N.; Whiteman, S.; Zwang, T. J.; Bacskai, B. J.

10.1101/2024.01.23.576662 — neuroscience — Posted on 2024-01-24

1176 Argon neuroprotection in a non-human primate model of transient endovascular ischemic stroke.

Torrecilla, S. G.; Delbrel, A.; Giacomino, L.; Meunier, D.; Sein, J.; Renaud, L.; Brige, P.; Garrigue, P.; Hak, J. F.; Guillet, B.; Brunel, H.; Farjot, G.; Brochier, T.; Velly, L.

10.1101/2024.01.24.577050 — neuroscience — Posted on 2024-01-24

1177 Reduced Capsaicin-Induced Mechanical Allodynia and Neuronal Responses in the DRG in the Presence of Shp1 Overexpression

Vroman, R.; Ishihara, S.; Fullam, S.; Wood, M. J.; Adamczyk, N. S.; Lomeli, N.; Malfait, F.; Malfait, A.-M.; Miller, R. E.; Markovics, A.

10.1101/2024.01.23.576758 — neuroscience — Posted on 2024-01-24

1178 Plasticity in inhibitory networks improves pattern separation in early olfactory processing

Joshi, S.; Haney, S.; Wang, Z.; Locatelli, F.; Smith, B.; Cao, Y.; Bazhenov, M.

10.1101/2024.01.24.576675 — neuroscience — Posted on 2024-01-24

1179 High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes

Zhang, L. A.; Li, P.; Callaway, E.

10.1101/2024.01.23.576944 — neuroscience — Posted on 2024-01-24

1180 Measuring excitation-inhibition balance through spectral components of local field potentials

Diehl, G. W.; Redish, A. D.

10.1101/2024.01.24.577086 — neuroscience — Posted on 2024-01-24

1181 Multisensory strategies for postural compensation after lateral line loss

Davis, S. N.; Zhu, Y.; Schoppik, D.

10.1101/2024.01.23.576760 — neuroscience — Posted on 2024-01-24

1182 Maternal fluoxetine impairs synaptic transmission and plasticity in the medial prefrontal cortex and alters the structure and function of dorsal raphe nucleus neurons in offspring mice

Bobula, B.; Bak, J.; Kania, A.; Siwiec, M.; Kielbinski, M.; Tokarski, K.; Palucha-Poniewiera, A.; Hess, G.

10.1101/2024.01.24.577094 — neuroscience — Posted on 2024-01-24

1183 Subject-specific maximum entropy model of resting state fMRI shows diagnostically distinct patterns of energy state distributions

Theis, N.; Bahuguna, J.; Rubin, J. E.; Cape, J. R.; IYENGAR, S.; Prasad, K. M.

10.1101/2024.01.23.576937 — neuroscience — Posted on 2024-01-24

1184 Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease

Shantaraman, A.; Dammer, E. B.; Ugochukwu, O.; Duong, D. M.; Yin, L.; Carter, E. K.; Gearing, M.; Chen-Plotkin, A.; Lee, E. B.; Trojanowski, J. Q.; Bennett, D. A.; Lah, J. J.; Levey, A. I.; Seyfried, N. T.; Higginbotham, L.

10.1101/2024.01.23.576728 — systems biology — Posted on 2024-01-24

1185 Variation in thermal sensitivity of diapause development among individuals and over time drives life history timing patterns in a univoltine insect

Toxopeus, J.; Dowle, E. J.; Andaloori, L.; Ragland, G. J.

10.1101/2023.05.31.543112 — physiology — Posted on 2024-01-24

1186 Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

Duplaquet, L.; So, K.; Ying, A. W.; Li, X.; Li, Y.; Qiu, X.; Li, R.; Singh, S.; Wu, X. S.; Liu, Q.; Qi, J.; Somerville, T. D. D.; Heiling, H.; Mazzola, E.; Lee, Y.; Zoller, T.; Vakoc, C. R.; Doench, J. G.; Forrester, W. C.; Abrams, T.; Long, H. W.; Niederst, M. J.; Kadoch, C.; Oser, M. G.

10.1101/2024.01.21.576304 — cancer biology — Posted on 2024-01-24

1187 The Investigation of Somatostatin Receptors as a Potential Target in Breast Phyllodes Tumours

Suer Mickler, H.; Erkan, M. M.

10.1101/2024.01.21.576520 — cancer biology — Posted on 2024-01-24

1188 Rbbp8nl contributes to resistance to anticancer immunotherapy by creating a non-inflamed tumor microenvironment and attenuating CD8+ T cell infiltration

Yi, Z.; Liu, J.; Deng, H.; Jiao, H.; Zu, X.

10.1101/2024.01.21.575810 — cancer biology — Posted on 2024-01-24

1189 Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent beta-catenin nuclear accumulation

Chocarro-Calvo, A.; Jociles-Ortega, M.; Garcia-Martinez, J. M.; Louphrasitthiphol, P.; Vivas-Garcia, Y.; RAMIREZ-SANCHEZ, A.; Chauhan, J.; FIUZA, M. C.; DURAN, M.; GARCIA-JIMENEZ, C.; GODING, C.

10.1101/2024.01.21.576568 — cancer biology — Posted on 2024-01-24

1190 New peptides against B16F10 interfere in cell cycle of melanoma cells

Xavier, E. A.

10.1101/2024.01.21.576573 — cancer biology — Posted on 2024-01-24

1191 The Notch1/Delta-like-4 axis is crucial for the initiation and progression of oral squamous cell carcinoma

Meisel, C. T.; Destefani, R.; Valookkaran, I. J.; Batavia, A.; Rupp, N.; Porcheri, C.; Mitsiadis, T.

10.1101/2024.01.21.576524 — cancer biology — Posted on 2024-01-24

1192 Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice

Hasanali, Z. S.; Garfall, A.; Burzenski, L.; Shultz, L.; Tang, Y.; Kadu, S.; Sheppard, N.; Dopkin, D.; Vogl, D. T.; Cohen, A. D.; Waxman, A. J.; Susanibar-Adaniya, S.; Carroll, M.; Stadtmauer, E.; Allman, D. M.

10.1101/2024.01.21.576547 — cancer biology — Posted on 2024-01-24

1193 SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells.

Garcia-Martinez, J. M.; Chocarro-Calvo, A.; Martinez-Useros, J.; Regueira-Acebedo, N.; Fernandez-Acenero, M. J.; Munoz, A.; Larriba, M. J.; Garcia-Jimenez, C.

10.1101/2024.01.21.576539 — cancer biology — Posted on 2024-01-24

1194 Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer

Zhang, R.; Hu, M.; Liu, Y.; Li, W.; Xu, Z.; He, S.; Lu, Y.; Gong, Y.; Wang, X.; Hai, S.; Li, S.; Qi, S.; Li, Y.; Shu, Y.; Du, D.; Zhang, H.; Xu, H.; Zhou, Z.; Lei, P.; Chen, H.-N.; Dai, L.

10.1101/2024.01.22.576593 — cancer biology — Posted on 2024-01-24

1195 LRMP inhibits the cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction

Bankston, J. R.; Proenza, C.; Peters, C. H.; Singh, R. K.; Langley, A. A.; Nichols, W. G.; Ferris, H. R.; Jeffrey, D. A.

10.1101/2023.08.29.555242 — biophysics — Posted on 2024-01-24

1196 From initial RNA encoding to the Standard Genetic Code

Yarus, M.

10.1101/2023.11.07.566042 — evolutionary biology — Posted on 2024-01-24

1197 Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in the mouse

Kruger, R.; Frum, T.; Brumm, A. S.; Hickey, S. L.; Niakan, K.; Aziz, F.; Shammami, M.; Roberts, J.; Ralston, A.

10.1101/2024.01.23.576717 — developmental biology — Posted on 2024-01-24

1198 Arp2/3 mediated dynamic lamellipodia of the hPSC colony edges promote liposome-based DNA delivery

Surma, M.; Anbarasu, K.; Das, A.

10.1101/2021.05.16.444342 — cell biology — Posted on 2024-01-24

1199 Is the distribution of plasmid lengths bimodal?

Dewan, I.; Uecker, H.

10.1101/2023.09.10.557055 — microbiology — Posted on 2024-01-24

1200 Brain-phenotype predictions can survive across diverse real-world data

Adkinson, B. D.; Rosenblatt, M.; Dadashkarimi, J.; Tejavibulya, L.; Jiang, R.; Noble, S.; Scheinost, D.

10.1101/2024.01.23.576916 — neuroscience — Posted on 2024-01-24

1201 The immunological profile of RC17 hESC-derived dopaminergic neural progenitor cells in vitro: implications for the STEM-PD clinical trial.

Curle, A. J.; Fazal, S. V.; Qarin, S.; Howlett, S. K.; He, X.; Barker, R. A.; Jones, J. L.

10.1101/2024.01.23.576826 — neuroscience — Posted on 2024-01-24

1202 Bayesian evidence for the neural dissociation between finger and hand imitation skills

Rosenzopf, H.; Roehrig, L.; Goldenberg, G.; Karnath, H.-O.

10.1101/2024.01.23.576674 — neuroscience — Posted on 2024-01-24

1203 BETA-HYDROXYBUTYRATE COUNTERACTS THE DELETERIOUS EFFECTS OF A SATURATED HIGH-FAT DIET ON SYNAPTIC AMPA RECEPTORS AND COGNITIVE PERFORMANCE

Rojas, R.; Grinan-Ferre, C.; Castellanos, A.; Griego, E.; Martinez, M.; Navarro-Lopez, J. d. D.; Jimenez-Diaz, L.; Rodriguez-Alvarez, J.; Soto del Cerro, D.; Castillo, P. E.; Pallas, M.; Fado, R.; Casals, N.

10.1101/2024.01.23.576931 — neuroscience — Posted on 2024-01-24

1204 Radial askew endodermal cell divisions reveal IRK functions in division orientation

Rony, R. I. K.; Campos, R.; Perez Henriquez, P.; Van Norman, J. M.

10.1101/2023.03.31.534810 — plant biology — Posted on 2024-01-24

1205 Low-intensity transcranial focused ultrasound suppresses pain by modulating pain processing brain circuits

Kim, M. G.; Yu, K.; Yeh, C.-Y.; Fouda, R.; Argueta, D.; Kiven, S.; Ni, Y.; Niu, X.; Chen, Q.; Kim, K.; Gupta, K.; He, B.

10.1101/2022.12.07.519518 — bioengineering — Posted on 2024-01-24

1206 Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding scavenger receptor B1

Fung, K.; Ho, T. W. W.; Xu, Z.; Neculai, D.; Beauchemin, C.; Lee, W.; Fairn, G. D.

10.1101/2022.08.08.503162 — biochemistry — Posted on 2024-01-24

1207 Comparative analysis of multiplexed in situ gene expression profiling technologies

Hartman, A.; Satija, R.

10.1101/2024.01.11.575135 — genomics — Posted on 2024-01-24

1208 Exploring the ageing methylome in the model insect,Nasonia vitripennis

Brink, K.; Thomas, C.; Jones, A.; Chan, T. W.; Mallon, E. B.

10.1101/2023.02.14.528436 — genomics — Posted on 2024-01-24

1209 High response diversity and conspecific density-dependence, not species interactions, drive dynamics of coral reef fish communities

Ruiz-Moreno, A.; Emslie, M. J.; Connolly, S. R.

10.1101/2024.01.23.576565 — ecology — Posted on 2024-01-24

1210 Quantifying microbial guilds

Rivas-Santisteban, J.; Yubero, P.; Robaina-Estevez, S.; Gonzalez, J. M.; Tamames, J.; Pedros-Alio, C.

10.1101/2023.07.23.550202 — ecology — Posted on 2024-01-24

1211 Underlying molecular effects to behavioral consequences present line of evidence for zebrafish eye development and function alteration by crude oil exposure.

Mueller, L. K.; Johann, S.; Denecke, B.; Abdallah, A. T.; Hecker, M.; Hollert, H.; Seiler, T.-B.

10.1101/2024.01.23.576882 — developmental biology — Posted on 2024-01-24

1212 Cell cycle length regulates heterochromatin reprogramming during early development in non-mammalian vertebrates

Fukushima, H. S.; Ikeda, T.; Ikeda, S.; Takeda, H.

10.1101/2024.01.23.576847 — developmental biology — Posted on 2024-01-24

1213 VEGF counteracts shear stress-determined arterial fate specification during capillary remodeling.

Chen, D.; Rukhlenko, O. S.; Coon, B. G.; Joshi, D.; Chakraborty, R.; Martin, K. A.; Kholodenko, B. N.; Schwartz, M. A.; Simons, M.

10.1101/2024.01.23.576920 — developmental biology — Posted on 2024-01-24

1214 An important role for triglyceride in regulating spermatogenesis

Chao, C. F.; Pesch, Y.-Y.; Yu, H.; Wang, C.; Aristizabal, M. J.; Huan, T.; Tanentzapf, G.; Rideout, E.

10.1101/2022.12.16.520841 — developmental biology — Posted on 2024-01-24

1215 Alterations of genomic imprinting appear during the reprogramming of adult neural stem cells

Montalban-Loro, R.; Lozano-Urena, A.; Lazaro-Carot, L.; Jimenez-Villalba, E.; Planells, J.; Lleches-Padilla, A.; Ito, M.; Radford, E.; Ferron, S. M.

10.1101/2024.01.23.576820 — cell biology — Posted on 2024-01-24

1216 Transcriptomic Profile of Lin-Sca1+c-kit (LSK) cells in db/db mice with long-standing diabetes

Mahajan, N.; Luo, Q.; Abhyankar, S.; Bhatwadekar, A. D.

10.1101/2024.01.22.576754 — cell biology — Posted on 2024-01-24

1217 ZNF827 pleiotropic cardiovascular risk locus involves regulation by Nuclear factor-1

Liu, Y.; Liu, L.; Esmael, A.; Fustier, M.-A.; Georges, A.; Bouatia-Naji, N.

10.1101/2024.01.23.576845 — cell biology — Posted on 2024-01-24

1218 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids

Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Wang, M.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.

10.1101/2023.04.25.538102 — cell biology — Posted on 2024-01-24

1219 Structure-Guided Mutagenesis Targeting Interactions between pp150 Tegument Protein and Small Capsid Protein Identify Five Lethal and Two Live Attenuated HCMV Mutants

Stevens, A. W.; Cruz-Cosme, R.; Armstrong, N.; Tang, Q.; Zhou, Z. H.

10.1101/2024.01.22.576707 — microbiology — Posted on 2024-01-24

1220 CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment

Kar, M.; Johnson, K. E. E.; Vanderheiden, A.; Elrod, E. J.; Floyd, K.; Geerling, E.; Stone, E. T.; Salinas, E.; Banakis, S.; Wang, W.; Sathish, S.; Shrihari, S.; Davis-Gardner, M. E.; Kohlmeier, J.; Pinto, A.; Klein, R.; Grakoui, A.; Ghedin, E.; Suthar, M. S.

10.1101/2024.01.23.576505 — immunology — Posted on 2024-01-24

1221 A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

Rozak, M. W.; Mester, J. R.; Attarpour, A.; Dorr, A.; Goubran, M.; Stefanovic, B.

10.1101/2024.01.24.577045 — neuroscience — Posted on 2024-01-24

1222 Astrocytes tune neuronal excitability through the calcium-activated potassium current sIAHP

Martin, E. D.; Exposito, S.; Alberquilla, S.

10.1101/2024.01.24.576973 — neuroscience — Posted on 2024-01-24

1223 Balancing safety and efficiency in human decision making

Mahajan, P.; Tong, S.; Lee, S. W.; Seymour, B.

10.1101/2024.01.23.576678 — neuroscience — Posted on 2024-01-24

1224 Biophysical Essentials - A Full Stack Open-Source Software Framework for Conserved and Advanced Analysis of Patch-Clamp Recordings

Zimmermann, D.; Kress, M.; Zeidler, M.

10.1101/2024.01.24.576881 — neuroscience — Posted on 2024-01-24

1225 Frontal noradrenergic and cholinergic transients exhibit distinct spatiotemporal dynamics during competitive decision-making

Wang, H.; Ortega, H. K.; Kelly, E. B.; Indajang, J.; Feng, J.; Li, Y.; Kwan, A. C.

10.1101/2024.01.23.576893 — neuroscience — Posted on 2024-01-24

1226 Nr4a2 blocks oAbeta-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the APPSw,Ind mouse

Catala Solsona, J.; Lutzu, S.; Lituma, P. J.; Fabregas Ordonez, C.; Siedlecki, D.; Gimenez-Llort, L.; Minano-Molina, A. J.; Saura, C. A.; Castillo, P. E.; Rodriguez Alvarez, J.

10.1101/2024.01.24.577010 — neuroscience — Posted on 2024-01-24

1227 PP2B-dependent cerebellar plasticity sets the amplitude of an innate reflex during juvenile development

Wu, B.; Post, L.; Lin, Z.; Schonewille, M.

10.1101/2024.01.24.576981 — neuroscience — Posted on 2024-01-24

1228 A functional interaction between TDP-43 and USP10 reveals USP10 dysfunction in TDP-43 proteinopathies

Marrero-Gagliardi, A.; Noda, J.; Zanovello, M.; Armas, J. M. B.; Bampton, A.; Torres, P.; Perez, C.; Fumagallo, F.; Taoro, L.; Alfaro, R. A. M. d. B.; Brown, A. L.; Quinet, G.; Andres-Benito, P.; Ferrer, I.; Acebes, A.; Freire, R.; Smits, V. A. J.; Keuss, M.; Portero-Otin, M.; Lashley, T.; Fratta, P.; Acevedo-Arozena, A.

10.1101/2024.01.23.576828 — neuroscience — Posted on 2024-01-24

1229 An inductive bias for slowly changing features in human reinforcement learning

Hedrich, N. L.; Schulz, E.; Hall-McMaster, S.; Schuck, N. W.

10.1101/2024.01.24.576910 — neuroscience — Posted on 2024-01-24

1230 Differential contribution of distinct neuronal populations to danger representations

Menegolla, A. P.; Lopez-Fernandez, G.; Herry, C.; Martin-Fernandez, M.

10.1101/2024.01.24.577067 — neuroscience — Posted on 2024-01-24

1231 Rat anterior cingulate neurons responsive to rule or strategy changes are modulated by the hippocampal theta rhythm and sharp-wave ripples

Khamassi, M.; Peyrache, A.; Benchenane, K.; Hopkins, D.; Lebas, N.; Douchamps, V.; Droulez, J.; Battaglia, F. P.; Wiener, S. I.

10.1101/2024.01.24.577008 — neuroscience — Posted on 2024-01-24

1232 Sertraline modulates hippocampal plasticity and learning via sigma 1 receptors, cellular stress and neurosteroids

Izumi, Y.; Reiersen, A. M.; Lenze, E. J.; Mennerick, S.; Zorumski, C. F.

10.1101/2024.01.23.576911 — neuroscience — Posted on 2024-01-24

1233 Propofol Disrupts the Functional Core-Matrix Architecture of the Thalamus in Humans

Huang, Z.; Mashour, G. A.; Hudetz, A. G.

10.1101/2024.01.23.576934 — neuroscience — Posted on 2024-01-24

1234 Vanillin flavor in e-liquids does not induce endothelial cell dysfunction: the Replica Project

Emma, R.; Sun, A.; Partsinevelos, K.; Rust, S.; Volarevic, V.; Lesmana, R.; Giordano, A.; Barliana, M. I.; Arsenijevic, A.; Kastratovic, N.; Markovic, V.; Distefano, A.; Orlando, L.; Carota, G.; Polosa, R.; Caruso, M.; Li Volti, G.

10.1101/2024.01.20.576442 — pharmacology and toxicology — Posted on 2024-01-24

1235 CAT Bridge: an efficient toolkit for compound-transcript association mining from multi-omics data

Yang, B.; Meng, T.; Wang, X.; Li, J.; Zhao, S.; Wang, Y.; Yi, S.; Zhou, Y.; Zhang, Y.; Li, L.; Guo, L.

10.1101/2024.01.21.576587 — bioinformatics — Posted on 2024-01-24

1236 Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site

Bimai, O.; Banerjee, I.; Grinberg, I. R.; Huang, P.; Hultgren, L.; Ekström, S.; Lundin, D.; Sjöberg, B.-M.; Logan, D. T.

10.1101/2023.06.20.545753 — biochemistry — Posted on 2024-01-24

1237 C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

Consalvo, C. D.; Aderounmu, A. M.; Donelick, H. M.; Aruscavage, P. J.; Eckert, D. M.; Shen, P. S.; Bass, B. L.

10.1101/2023.09.21.558868 — biochemistry — Posted on 2024-01-24

1238 Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration.

Gray, N. E.; Hack, W.; Brandes, M.; Zweig, J. A.; Yang, L.; Marney, L.; Choi, J.; Magana, A. A.; Cerruit, N.; McFerrin, J.; Koike, S.; Nguyen, T.; Raber, J.; Quinn, J. F.; Maier, C. S.; Soumyanath, A.

10.1101/2024.01.23.576700 — animal behavior and cognition — Posted on 2024-01-24

1239 When the tap runs dry: The multi-tissue gene expression and physiological responses of water deprived Peromyscus eremicus

Blumstein, D.; MacManes, M.

10.1101/2024.01.22.576658 — genomics — Posted on 2024-01-24

1240 TET3 regulates cellular terminal differentiation at the metabolic level

Mulet, I.; Grueso-Cortina, C.; Cortes-Cano, M.; Gerovska, D.; Wu, G.; Jimenez-Blasco, D.; Curtabbi, A.; Hernansanz-Agustin, P.; Manjarres-Raza, I.; Bolanos, J. P.; Enriquez, J. A.; Arauzo-Bravo, M. J.; Tapia, N.

10.1101/2024.01.23.576868 — developmental biology — Posted on 2024-01-24

1241 Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes

Moorwood, K.; Smith, F. M.; Garfield, A. S.; Ward, A.

10.1101/2024.01.24.576998 — developmental biology — Posted on 2024-01-24

1242 An optimized live imaging and growth analysis approach for Arabidopsis Sepals

Yadav, A. S.; Roeder, A.

10.1101/2024.01.22.576735 — developmental biology — Posted on 2024-01-24

1243 Wnt/β-catenin signaling improves oxidative metabolism in skeletal muscle of obese ob/ob mice

Christodoulou, E.; Lepeigneux, C.; Naviere, A.; Pujol, J.; Benhamed, F.; Maire, P.; Guillet-Deniau, I.

10.1101/2024.01.23.576856 — cell biology — Posted on 2024-01-24

1244 Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Pal, S.; Su, Y.; Claesson-Welsh, L.; Richards, M.

10.1101/2024.01.23.576785 — cell biology — Posted on 2024-01-24

1245 Extracellular matrix signals promotes actin-dependent mitochondrial elongation and activity

Gatti, P.; Mukherjee, P.; Talukdar, P. D.; Freppel, W.; Kanou, J.; Chatel-Chaix, L.; Chatterji, U.; Germain, M.

10.1101/2024.01.22.576703 — cell biology — Posted on 2024-01-24

1246 Autism spectrum disorders: an impaired glycolysis induces an ATP deficiency and a reduced cell respiration

FERON, F.; CAILLOL, D.; FOUREL, L.; LEIMKUHLER, S.; IRANZO, O.; GEPNER, B.; GUIRAUDIE-CAPRAZ, G.

10.1101/2024.01.22.576644 — cell biology — Posted on 2024-01-24

1247 Retinoic acid generates a beneficial microenvironment for liver progenitor cell activation in acute liver failure

Wang, S.; Link, F.; Munker, S.; Wang, W.; Feng, R.; Lieber, R.; Li, Y.; Yao, Y.; Liu, H.; Shao, C.; Ebert, M.; Ding, H.; Dooley, S.; Weng, H.; Wang, S.

10.1101/2024.01.23.576749 — cell biology — Posted on 2024-01-24

1248 TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport

Wu, H.; Wang, L. C.; Sow, B.; Leow, D.; Zhu, J.; Gallo, K.; Wilsbach, K.; Gupta, R.; Ostrow, L.; Yeo, C.; Sobota, R.; Li, R.

10.1101/2024.01.24.576891 — cell biology — Posted on 2024-01-24

1249 Cell surface morphology mimicking nano-bio platform for immune cell stimulation

Varghese, B.; Gonzalez-Navarro, J. A.; Guerra, V. L. P.; Faizulina, M.; Artemieva, D.; Chum, T.; Ramakrishna, T. R. B.; Cebecauer, M.; Kovaricek, P.

10.1101/2024.01.23.576453 — cell biology — Posted on 2024-01-24

1250 Regulatory T cells and IFN-γ-producing Th1 cells play a critical role in the pathogenesis of Sjögren's Syndrome

Wang, Y.-H.; Li, W.; McDermott, M.; Son, G.-Y.; Maiti, G.; Zhou, F.; Tao, A. Y.; Raphael, D.; Moreira, A. L.; Shen, B.; Vaeth, M.; Nadorp, B.; Chakravarti, S.; Lacruz, R. S.; Feske, S.

10.1101/2024.01.23.576314 — immunology — Posted on 2024-01-24

1251 IL-17A/IFN-γ producing γ δ T cell functional dichotomy impacts cutaneous leishmaniasis in mice

Dos-Santos, J. S.; Firmino-Cruz, L.; Oliveira-Maciel, D.; da Fonseca-Martins, A. M.; Ramos, T. D.; Nunes-Souza, L.; Soares, R. P.; Gomes, D. C. O.; Mengel, J. O.; Silva-Santos, B.; de Matos Guedes, H. L.

10.1101/2024.01.22.576494 — immunology — Posted on 2024-01-24

1252 Treatment effects in epilepsy: a mathematical framework for understanding response over time

Harrington, G.; Kissack, P.; Terry, J. R.; Woldman, W.; Junges, L.

10.1101/2024.01.22.576627 — neuroscience — Posted on 2024-01-24

1253 The bistable mitotic switch in fission yeast

Novak, B.; Tyson, J. J.

10.1101/2024.01.23.576917 — systems biology — Posted on 2024-01-24

1254 Comparison of the performance of multiple whole-genome sequence-based tools for the identification of Bacillus cereus sensu stricto biovar Thuringiensis

Chung, T.; Salazar, A.; Harm, G.; Johler, S.; Carroll, L. M.; Kovac, J.

10.1101/2024.01.23.575246 — bioinformatics — Posted on 2024-01-24

1255 High-throughput selection of human de novo-emerged sORFs with high folding potential

Aubel, M.; Buchel, F.; Heames, B.; Jones, A. R. C.; Honc, O.; Bornberg-Bauer, E.; Hlouchova, K.

10.1101/2024.01.22.576604 — evolutionary biology — Posted on 2024-01-24

1256 Adaptive advantage of deletion repair in the N terminal domain of the SARS-CoV-2 spike protein in variants of concern

Alvarez-Herrera, M.; Ruiz-Rodriguez, P.; Navarro-Dominguez, B.; Zulaica, J.; Grau, B.; Bracho, M. A.; Guerreiro, M.; Aguilar-Gallardo, C.; Gonzalez-Candelas, F.; Comas, I.; Geller, R.; Coscolla, M.

10.1101/2024.01.23.575696 — evolutionary biology — Posted on 2024-01-24

1257 Phylogenomics reveals coincident divergence between giant host sea anemones and the clownfish adaptive radiation.

De Jode, A.; Quattrini, A.; Chiodo, T.; Daly, M.; McFadden, C. S.; Berumen, M. L.; Meyer, C. P.; Mills, S.; Beldade, R.; Scott, A.; Bartholomew, A.; Reimer, J. D.; Yanagi, K.; Fuji, T.; Rodriguez, E.; Titus, B. M.

10.1101/2024.01.24.576469 — evolutionary biology — Posted on 2024-01-24

1258 Med12 cooperates with multiple differentiation signals to enhance embryonic stem cell plasticity

Fernkorn, M.; Schröter, C.

10.1101/2024.01.22.576603 — cell biology — Posted on 2024-01-24

1259 JAK/STAT signaling promotes the emergence of unique cell states in ulcerative colitis

Maciag, G.; Hansen, S.; Krizic, K.; Kellermann, L.; Ulyanchenko, S.; Maimets, M.; Baattrup, A.; Riis, L.; Khodosevich, K.; Sato, T.; Nielsen, O. H.; Jensen, K.

10.1101/2024.01.22.576736 — cell biology — Posted on 2024-01-24

1260 The modified activity of prolyl 4 hydroxylases (P4Hs) reveals the effect of arabinogalactan proteins (AGPs) on changes in the cell wall during the tomato ripening process

Kutyrieva-Nowak, N.; Leszczuk, A.; Ezzat, L.; Kaloudas, D.; Zajac, A.; Szymanska-Chargot, M.; Skrzypek, T.; Krokida, A.; Mekkaoui, K.; Lampropoulou, E.; Kalaitzis, P.; Zdunek, A.

10.1101/2024.01.22.576594 — plant biology — Posted on 2024-01-24

1261 Treatment of a genetic liver disease in mice through transient prime editor expression

Rothgangl, T.; Ioannidi, E. I.; Weber, Y.; Talas, A.; Boeck, D.; Matsushita, M.; Villiger, E. A.; Schmidheini, L.; Moon, J.; Lin, P. J. C.; Fan, S. H. Y.; Marquart, K. F.; Schwerdel, C.; Rimann, N.; Faccin, E.; Cremonesi, A.; Villiger, L.; Muramatsu, H.; Vadovics, M.; Thoeny, B.; Kopf, M.; Haeberle, J.; Pardi, N.; Tam, Y. K.; Schwank, G.

10.1101/2024.01.22.575834 — bioengineering — Posted on 2024-01-24

1262 Reproducing within-reef variability in coral dynamics with a metacommunity modelling framework

Cresswell, A. K.; Haller-Bull, V.; Gonzalez-Rivero, M.; Gilmour, J. P.; Bozec, Y.-M.; Barneche, D. R.; Robson, B.; Anthony, K.; Doropoulos, C.; Roelfsema, C. M.; Lyons, M.; Mumby, P. J.; Condie, S.; Lago, V.; Ortiz, J.-C.

10.1101/2024.01.21.576579 — ecology — Posted on 2024-01-24

1263 Development of Ingenui-T, a Novel Vein-to-Vein Solution for Rapid Autologous CAR T-Cell Manufacturing Starting From Whole Blood, for the Treatment of Autoimmune Diseases

Anaya, D.; Kwong, B.; Park, S.; Biswas, S.; Jeevan, J.; Strobach, M.; Khoshnoodi, N.; Register, A.; Klasson, T.; Foos-Russ, S.; Zeng, J.; Banuelos, J.; Gibson, C.; Bravo, J.; Flandez, J.; Van Blarcom, T.; Walker, K.

10.1101/2024.01.24.576713 — immunology — Posted on 2024-01-24

1264 The SUbventral-Gland master Regulator (SUGR) of nematode virulence

Pellegrin, C.; Damm, A.; Sperling, A. L.; Molloy, B.; Shin, D. S.; Long, J.; Brett, P.; Bravo, A. D.-T.; Lynch, S. J.; Senatori, B.; Vieira, P.; Mejias, J.; Kumar, A.; Masonbrink, R. E.; Maier, T. R.; Baum, T. J.; Eves-van den Akker, S.

10.1101/2024.01.22.576598 — pathology — Posted on 2024-01-24

1265 scaDA: A Novel Statistical Method for Differential Analysis of Single-Cell Chromatin Accessibility Sequencing Data

Chen, L.; Zhao, F.; Ma, X.; Yao, B.

10.1101/2024.01.21.576570 — bioinformatics — Posted on 2024-01-24

1266 WITHDRAWN: Plasmodium exoerythrocytic parasites redirect trafficking of human proteins to the parasitophorous vacuole

Calla, J.; Mittal, N.; LaMonte, G.; Liffner, B.; Godinez-Macias, K.; Carolino, K.; Walker, G. T.; Zou, B. Y.; Paytas, E.; Guerra, L.; Tong-Rios, C.; Campo, B.; Vinetz, J. M.; Gamboa, D.; Raffatellu, M.; Absalon, S.; Winzeler, E.

10.1101/2022.11.22.517223 — cell biology — Posted on 2024-01-24

1267 The interferon-γ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

Sutter, S. O.; Tobler, K.; Seyffert, M.; Lkharrazi, A.; Zöllig, J.; Schraner, E. M.; Vogt, B.; Büning, H.; Fraefel, C.

10.1101/2024.01.22.576730 — microbiology — Posted on 2024-01-24

1268 The TOR signaling pathway regulates vegetative development, aflatoxin biosynthesis, and pathogenicity in Aspergillus flavus

Li, G.; Cao, X.; Tumukunde, E.; Zeng, Q.; Wang, S.

10.1101/2023.06.18.545466 — microbiology — Posted on 2024-01-24

1269 FLUAV RAM-IGIP: A modified live influenza virus vaccine that enhances humoral and mucosal responses against influenza

Caceres, C. J.; Gay, L. C.; Jain, A.; Mejias, T.; Cardenas Perez, M.; Seibert, B. A.; Faccin, F.; Cowan, B.; Geiger, G.; Vincent Baker, A. L.; Carnaccini, S.; Davies, D. H.; Rajao, D. S.; Perez, D. R.

10.1101/2024.01.23.576908 — immunology — Posted on 2024-01-24

1270 Single-domain antibodies reveal unique borreliacidal epitopes on the Lyme disease vaccine antigen, Outer surface protein A (OspA)

Vance, D. J.; Basir, S.; Piazza, C. L.; Willsey, G.; Haque, H. M. E.; Tremblay, J. M.; Rudolph, M. J.; Muriuki, B.; Cavacini, L. A.; Weis, D. D.; Shoemaker, C. B.; Mantis, N. J.

10.1101/2024.01.23.576890 — immunology — Posted on 2024-01-24

1271 Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain

Lin, Y.-H.; Wang, L.-W.; Chen, Y.-H.; Chan, Y.-C.; Hu, S.-H.; Wu, S.-Y.; Chiang, C.-S.; Huang, G.-J.; Yang, S.-D.; Chu, S.-W.; Wang, K.-C.; Lin, C.-H.; Huang, P.-H.; Cheng, H.-J.; Chen, B.-C.; Chu, L.-A.

10.1101/2022.11.28.518189 — neuroscience — Posted on 2024-01-24

1272 Minimizing variability in the filament middle cerebral artery occlusion model in C57BL/6 mice by surgical optimization - the PURE-MCAo Model

Yoshimura, S.; Dorok, M.; Mamrak, U.; Wehn, A.; Krestel, E.; Khalin, I.; Plesnila, N.

10.1101/2024.01.22.576769 — neuroscience — Posted on 2024-01-24

1273 Dynamic categorization rules alter representations in human visual cortex

Henderson, M. M.; Serences, J. T.; Rungratsameetaweemana, N.

10.1101/2023.09.11.557257 — neuroscience — Posted on 2024-01-24

1274 Investments in photoreceptors compete with investments in optics to determine eye design

Heras, F. J. H.; Laughlin, S. B.

10.1101/2024.01.21.576511 — zoology — Posted on 2024-01-24

1275 Feline tooth resorption in a case-control study based on a subpopulation of 944 dentally examined cats from a Finnish questionnaire survey of over 8000 cats

Vapalahti, K.; Neittaanmäki, H.; Lohi, H.; Virtala, A.-M.

10.1101/2021.01.22.427753 — pathology — Posted on 2024-01-24

1276 Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and cell fate in ovarian cancer.

Javed, Z.; Shin, D. H.; Pan, W.; White, S. R.; Kim, Y. S.; Elhaw, A. T.; Kamlapurkar, S.; Cheng, Y.-Y.; Benson, J. C.; Abdelnaby, A. E.; Phaeton, R.; Wang, H.-G.; Yang, S.; Sullivan, M. L. G.; St. Croix, C.; Watkins, S. C.; Mullett, S. J.; Gelhaus, S. L.; Lee, N. Y.; Coffman, L.; Aird, K. M.; Trebak, M.; Karthikeyan, M.; Walter, V.; Hempel, N.

10.1101/2023.09.20.558501 — cancer biology — Posted on 2024-01-24

1277 A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer

Foote, J.; Mattox, T. E.; Keeton, A. B.; Chen, X.; Smith, F. T.; Berry, K. L.; Holmes, T. W.; Wang, J.; Wang, C.-H.; Ward, A. B.; Hardy, C.; Fleten, K. G.; Flatmark, K.; Yoon, K. J.; Sarvesh, S.; Nagaraju, G. P.; Maxuitenko, Y.; Valiyaveettil, J.; Carstens, J. L.; Buchsbaum, D. J.; Yang, J.; Zhou, G.; Nurmmedov, E.; Babic, I.; Gaponenko, V.; Abdelkarim, H.; Mitra, A. K.; Boyd, M. R.; Manne, U.; Bae, S.; El-Rayes, B. F.; Piazza, G. A.

10.1101/2023.05.17.541233 — cancer biology — Posted on 2024-01-24

1278 Characterization of Cancer Stem Cells in Laryngeal Squamous Cell Carcinoma by Single-Cell RNA Sequencing

Li, Y.; Lin, C.; Chu, Y.; Wei, Z.; Ding, Q.; Gu, S.; Deng, H.; Liao, Q.; Shen, Z.

10.1101/2024.01.21.576534 — bioinformatics — Posted on 2024-01-24

1279 PRRGO: A Tool for Visualizing and Mapping Globally Expressed Genes in Public Gene Expression Omnibus RNA-Sequencing Studies to PageRank-scored Gene Ontology Terms

Solano, L. E.; D'Sa, N.; Nikolaidis, N.

10.1101/2024.01.21.576540 — bioinformatics — Posted on 2024-01-24

1280 Community-aware explanations in knowledge graphs with XP-GNN

Martinez Mora, A.; Nilsson, S.; Polychronopoulos, D.; Ughetto, M.

10.1101/2024.01.21.576302 — bioinformatics — Posted on 2024-01-24

1281 A Comprehensive Evaluation of Large Language Models in Mining Gene Interactions and Pathway Knowledge

Azam, M.; Chen, Y.; Arowolo, M.; Liu, H.; Popescu, M.; Xu, D.

10.1101/2024.01.21.576542 — bioinformatics — Posted on 2024-01-24

1282 NeuralTE: an accurate approach for Transposable Element superfamily classification with multi-feature fusion

Hu, K.; Xu, M.; Gao, X.; Wang, J.

10.1101/2024.01.21.576519 — bioinformatics — Posted on 2024-01-24

1283 edgeR 4.0: powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and larger datasets

Chen, Y.; Chen, L.; Lun, A. T. L.; Baldoni, P. L.; Smyth, G. K.

10.1101/2024.01.21.576131 — bioinformatics — Posted on 2024-01-24

1284 The Molecular Signature Associated with Oxaliplatin-Induced Peripheral Neuropathy in Colorectal Cancer

Modekurty, S.

10.1101/2024.01.21.576583 — bioinformatics — Posted on 2024-01-24

1285 The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the antiviral innate immune response

Woltz, R.; Schweibenz, B.; Tsutakawa, S. E.; Zhao, C.; Ma, L.-C.; Shurina, B.; Hura, G. L.; John, R.; Vorobiev, S.; Gurla, S.; Solotchi, M.; Tainer, J. A.; Krug, R. M.; Patel, S. S.; Montelione, G. T.

10.1101/2023.09.25.559316 — biochemistry — Posted on 2024-01-24

1286 The chromosome-level genome of the ctenophore Mnemiopsis leidyi A. Agassiz, 1865 reveals a unique immune gene repertoire

Koutsouveli, V.; Torres-Oliva, M.; Bayer, T.; Fuss, J.; Grossschmidt, N.; Marulanda-Gomez, A. M.; Gill, D.; Schmitz, R. A.; Pita, L.; Reusch, T. B. H.

10.1101/2024.01.21.574862 — genomics — Posted on 2024-01-24

1287 Haplotype phased genome of 'Fairchild' mandarin highlights influence of local chromatin state on gene expression

Diaz, I. A.; Ostovar, T.; Chen, J.; Saddoris, S.; Schmitz, R. J.; Wessler, S. R.; Stajich, J.; Seymour, D. K.

10.1101/2024.01.20.575729 — genomics — Posted on 2024-01-24

1288 A potential role of inefficient and non-specific piRNA production from the whole transcriptome

Shoji, K.; Tomari, Y.

10.1101/2024.01.24.577019 — genetics — Posted on 2024-01-24

1289 Detecting directional epistasis and dominance from cross-line analyses in alpine populations of Arabidopsis thaliana

Le Rouzic, A.; Roumet, M.; Widmer, A.; Clo, J.

10.1101/2023.04.19.537438 — evolutionary biology — Posted on 2024-01-24

1290 Drivers of Bird Communities in an Urban Neighborhood Vary by Scale

Darracq, A. K.; Bliznick, C.; Yeager, R.; Turner, J.; Pease, J.; Whiteman, H.; Smith, T.; Bhatnagar, A.

10.1101/2024.01.21.576560 — ecology — Posted on 2024-01-24

1291 Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy

Martins, S. G.; Ribeiro, V.; Melo, C.; Paulino-Cavaco, C.; Antonini, D.; Dayalan Naidu, S.; Murtinheira, F.; Fonseca, I.; Saget, B.; Pita, M.; Fernandes, D. R.; dos Santos, P. G.; Rodrigues, G.; Zilhao, R.; Herrera, F.; Dinkova-Kostova, A. T.; Carlos, A. R.; Thorsteinsdottir, S.

10.1101/2024.01.20.576409 — developmental biology — Posted on 2024-01-24

1292 Interplay of Mycobacterium abscessus and Pseudomonas aeruginosa in coinfection: Biofilm Dynamics and Host Immune Response

Campo-Perez, V.; Julian, E.; Torrents, E.

10.1101/2024.01.22.576702 — microbiology — Posted on 2024-01-24

1293 Identifying the components of the Shewanella phage LambdaSo lysis system

Thöneböhn, S. W.; Fischer, D.; Kreiling, V.; Kemmler, A.; Oberheim, I. I.; Hager, F.; Schmid, N. E.; Thormann, K. M.

10.1101/2024.01.23.576932 — microbiology — Posted on 2024-01-24

1294 MoCHI: neural networks to fit interpretable models and quantify energies, energetic couplings, epistasis and allostery from deep mutational scanning data

Faure, A. J.; Lehner, B.

10.1101/2024.01.21.575681 — systems biology — Posted on 2024-01-24

1295 REPrise: de novo interspersed repeat detection using inexact seeding

Takeda, A.; Nonaka, D.; Imazu, Y.; Fukunaga, T.; Hamada, M.

10.1101/2024.01.21.576581 — bioinformatics — Posted on 2024-01-24

1296 Nuclear reassembly defects after mitosis trigger apoptotic and p53-dependent safeguard mechanisms in Drosophila

Li, J.; Jordana, L.; Mehsen, H.; Wang, X.; Archambault, V.

10.1101/2024.01.21.576567 — cell biology — Posted on 2024-01-24

1297 A novel in vivo model of Zika virus infection unveils NS4A as a key determinant of neuropathogenesis

Chatel-Chaix, L.; Sow, A. A.; Priyanka Jamadagni, P.; Scaturro, P.; Patten, S. A.

10.1101/2024.01.20.576493 — microbiology — Posted on 2024-01-24

1298 Natural genetic variation underlying the negative effect of elevated CO2 on ionome composition in Arabidopsis thaliana

Cassan, O.; Pimpare, L.-L.; Mozzanino, T.; Fizames, C.; Devidal, S.; Roux, F.; Milcu, A.; Lebre, S.; Gojon, A.; Martin, A.

10.1101/2023.06.05.543678 — plant biology — Posted on 2024-01-24

1299 Screening of leaf extraction and storage conditions for eco-metabolomics studies

Lang, J.; Ramos, S. E.; Smohunova, M.; Bigler, L.; Schuman, M. C.

10.1101/2023.06.26.546251 — plant biology — Posted on 2024-01-24

1300 Functionalising the electrical properties of Kombucha zoogleal mats for biosensing applications

Nikolaidou, A.; Chiolerio, A.; Dehshibi, M. M.; Adamatzky, A.

10.1101/2024.01.21.576528 — bioengineering — Posted on 2024-01-24

1301 Changes in spectral signature of leaves after desiccation: Implications for the prediction of leaf traits and plant-soil interaction in herbarium samples.

Quinteros Casaverde, N. L.; Serbin, S. P.; Daly, D. C.

10.1101/2024.01.21.576284 — ecology — Posted on 2024-01-24

1302 Unravelling Different Biological Roles Of Plant Synaptotagmins

Garcia-Hernandez, S.; Rubio, L.; Perez-Sancho, J.; Esteban del Valle, A.; Benitez-Fuente, F.; Beuzon, C.; Macho, A. P.; Ruiz-Lopez, N.; Albert, A.; Botella, M. A.

10.1101/2024.01.21.576508 — plant biology — Posted on 2024-01-24

1303 B-type plexins regulate mitosis via RanGTPase.

Mukhwana, N. J.; Garg, R.; Wiliamson, M.

10.1101/2024.01.21.576518 — cancer biology — Posted on 2024-01-24

1304 A Lipidomics Approach to Determine the Role of Lipids and its Crosstalk with Autophagy in Lung Cancer Metastasis

da Silva Rosa, S. C.; Alizadeh, J.; Vitorino, R.; Surendran, A.; Ravandi, A.; Kidane, B.; Ghavami, S.

10.1101/2024.01.01.573842 — cancer biology — Posted on 2024-01-24

1305 Cryptic female choice in response to male pheromones in Drosophila melanogaster

Doubovetzky, N.; Kohlmeier, P.; Bal, S.; Billeter, J.-C.

10.1101/2023.12.20.572608 — animal behavior and cognition — Posted on 2024-01-24

1306 Protected area establishment in Southern and Eastern Africa: Consequences for management today

Schroder, B.; Schroder, N.-A. H.; Van Langevelde, F.; Prins, H. H. T.

10.1101/2024.01.20.576490 — ecology — Posted on 2024-01-24

1307 Global Diversity in Mammalian Life Histories: Environmental Realms and Evolutionary Adaptations

Beccari, E.; Capdevila Lanzaco, P.; Salguero-Gomez, R.; Perez Carmona, C.

10.1101/2023.06.29.546851 — ecology — Posted on 2024-01-24

1308 Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis

Lee, J.; Liu, R.; Kim, B.; Zhang, Y.; Li, F.; Jagannathan, R.; Yang, P.; Negi, V.; Danvers, J.; Perez-Garcia, E. M.; Saha, P.; Sabek, O.; Creighton, C.; Coarfa, C.; Huising, M.; Shih, H. P.; Bottino, R.; Ma, K.; Moulik, M.; Yechoor, V.

10.1101/2020.03.05.979450 — molecular biology — Posted on 2024-01-24

1309 Impact of age versus hearing loss on amplitude modulation frequency selectivity and speech intelligibility

Regev, J.; Zaar, J.; Relano-Iborra, H.; Dau, T.

10.1101/2023.07.20.549841 — neuroscience — Posted on 2024-01-24

1310 Altered physiological, affective, and functional connectivity responses to acute stress in patients with alcohol use disorder

Schwarze, Y.; Voges, J.; Schröder, A.; Dreessen, S.; Voss, O.; Krach, S.; Paulus, F. M.; Junghanns, K.; Rademacher, L.

10.1101/2024.01.18.576207 — neuroscience — Posted on 2024-01-24

1311 Information Dynamics of the Heart and Respiration Rates: a Novel Venue for Digital Phenotyping in Humans

Keshmiri, S.; Tomonaga, S.; Mizutani, H.; Doya, K.

10.1101/2024.01.21.576502 — physiology — Posted on 2024-01-24

1312 Identification of a targetable ST2-expressing fibroblast subset driving Peutz-Jeghers syndrome polyposis

Domenech-Moreno, E.; Lim, W.-W.; Brandt, A.; Lemmetyinen, T.; Viitala, E.; Makela, T. P.; Cook, S.; Ollila, S.

10.1101/2023.11.29.568817 — cancer biology — Posted on 2024-01-24

1313 The D1 receptor agonist SKF38393 improves waiting impulsivity in a baseline dependent manner

Abdulkader, S. P.; Gigg, J.

10.1101/2023.07.15.549161 — animal behavior and cognition — Posted on 2024-01-24

1314 High interleukin-3 concentrations prime murine myeloid progenitor cells towards granulocytic differentiation

Hakobyan, M.; Rohdjess, H.; Lipka, D. B.

10.1101/2024.01.24.576972 — molecular biology — Posted on 2024-01-24

1315 Widespread Peptide Surfactants with Post-translational C-methylations Promote Bacterial Development

Zhang, C.; Seyedsayamdost, M. R.

10.1101/2024.01.23.576971 — biochemistry — Posted on 2024-01-24

1316 High-resolution Inference of Multiplexed Anti-HIV Gene Editing using Single-Cell Targeted DNA Sequencing

Bouzidi, M.; Dossani, Z.; Di Benedetto, C.; Raymond, K.; Desai, S.; Chavez, L.; Betancur, P.; Pillai, S. K.

10.1101/2024.01.24.576921 — genomics — Posted on 2024-01-24

1317 CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization

Serbynovskyi, V.; Wang, J.; Chua, E. Y. D.; Ishemgulova, A.; Alink, L. M.; Budell, W. C.; Johnston, J. D.; Dubbeldam, C.; Gonzalez, F. A.; Rozovsky, S.; Eng, E. T.; de Marco, A.; Noble, A. J.

10.1101/2024.01.23.576763 — molecular biology — Posted on 2024-01-24

1318 Endophytic and ectomycorrhizal, an overlooked dual ecological niche? Insights from natural environments and Russula species

Laurent-Webb, L.; Rech, P.; Bourceret, A.; Chaumenton, C.; Deveau, A.; Genola, L.; Januario, M.; Petrolli, R.; Selosse, M.-A.

10.1101/2024.01.24.576884 — microbiology — Posted on 2024-01-24

1319 Phylogenetically and structurally diverse reductive dehalogenases link biogeochemical cycles in deep-sea cold seeps

Han, Y.; Peng, Y.; Peng, J.; Cao, L.; Xu, Y.; Yang, Y.; Wu, M.; Zhou, H.; Zhang, C.; Zhang, D.; Wang, M.; Greening, C.; Dong, X.

10.1101/2024.01.23.576788 — microbiology — Posted on 2024-01-24

1320 Evaluation of Precision of the Plasmodium knowlesi Growth Inhibition Assay for Plasmodium vivax Duffy-Binding Protein-based Malaria Vaccine Development

Mertens, J. E.; Rigby, C. A.; Bardelli, M.; Quinkert, D.; Hou, M. M.; Diouf, A.; Silk, S. E.; Chitnis, C. E.; Minassian, A. M.; Moon, R. W.; Long, C. A.; Draper, S. J.; Miura, K.

10.1101/2024.01.23.576905 — immunology — Posted on 2024-01-24

1321 Curtailed CaSR expression in peripheral blood mononuclear cells is associated with hypertension

Bank, S.; Sarkar, K.; Chatterjee, A.; Das, A.; Chakraborty, S.; Malakar, S.; Pal, D.; Karmakar, S.; De, S.; Arumugam, S.; Das, M.

10.1101/2024.01.23.576550 — biochemistry — Posted on 2024-01-24

1322 Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding affinity and decreased artemisinin activation

Rahman, A.; Tamseel, S.; Coppee, R.; Dutta, S.; Khan, N.; Faaiz, M.; Rastogi, H.; Nath, J. R.; Chowdhury, P.; Ashish, A.; Clain, J.; Bhattacharjee, S.

10.1101/2024.01.23.576340 — biochemistry — Posted on 2024-01-24

1323 Embryonic piRNAs target horizontally transferred vertebrate transposons in assassin bugs

Brito, T. F. d.; Cardoso, M. A.; Atinbayeva, N.; Brito, I. A. d. A.; da Costa, L. A.; Iovino, N.; Pane, A.

10.1101/2024.01.22.576481 — genomics — Posted on 2024-01-24

1324 Overloading And unpacKing (OAK) - droplet-based combinatorial indexing for ultra-high throughput single-cell multiomic profiling

Wu, B.; Bennett, H. M.; Ye, X.; Sridhar, A.; Eidenschenk, C.; Everett, C.; Nazarova, E. V.; Chen, H.-H.; Kim, I. K.; Deangelis, M.; Owen, L. A.; Chen, C.; Lau, J.; Shi, M.; Lund, J. M.; Xavier-Magalhaes, A.; Patel, N.; Liang, Y.; Modrusan, Z.; Darmanis, S.

10.1101/2024.01.23.576918 — molecular biology — Posted on 2024-01-24

1325 Nano Colonies: Rearing honey bee queens and their offspring in small laboratory arenas

Lamas, Z. S.; Solmaz, S.; Stevens, C.; Bragg, J.; Ryabov, E. V.; Madella, S.; Corona, M.; Evans, J. D.

10.1101/2024.01.20.576222 — zoology — Posted on 2024-01-23

1326 The odor of a nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, is detected by specific olfactory sensory neurons of the green spotted puffers.

Suzuki, T.; Nakahigashi, R.; Adachi, M.; Nishikawa, T.; Abe, H.

10.1101/2023.08.22.552781 — zoology — Posted on 2024-01-24

1327 Transcriptome-wide analysis of cell cycle-dependent bursty gene expression from single-cell RNA-seq data using mechanistic model-based inference

Sukys, A.; Grima, R.

10.1101/2024.01.10.574820 — systems biology — Posted on 2024-01-23

1328 Active shape programming drives Drosophila wing disc eversion

Fuhrmann, J. F.; Krishna, A.; Paijmans, J.; Duclut, C. A.; Eaton, S.; Popovic, M.; Julicher, F.; Modes, C. D.; Dye, N. A.

10.1101/2023.12.23.573034 — biophysics — Posted on 2024-01-24

1329 Genomic Underground: Unraveling NUMTs in Mole Voles

Prokopov, D.; Saluev, T.; Romanenko, S.; Bakloushinskaya, I.; Graphodatsky, A.

10.1101/2023.12.30.573699 — genomics — Posted on 2024-01-23

1330 Whole-genome phylogenomics of the tinamous (Aves: Tinamidae): comparing gene tree estimation error between BUSCOs and UCEs illuminates rapid divergence with introgression

Musher, L. J.; Catanach, T. A.; Valqui, T.; Brumfield, R. T.; Aleixo, A.; Johnson, K. P.; Weckstein, J. D.

10.1101/2024.01.22.576737 — genomics — Posted on 2024-01-23

1331 How to measure bacterial genome plasticity? A novel time-integrated index helps gather insights on pathogens

Bellinzona, G.; Batisti Biffignandi, G.; Baldanti, F.; Brilli, M.; Sassera, D.; Gaiarsa, S.

10.1101/2024.01.22.576626 — genomics — Posted on 2024-01-23

1332 Aggregation of recount3 RNA-seq data improves the inference of consensus and tissue-specific gene co-expression networks.

Ravichandran, P.; Parsana, P.; Keener, R.; Hansen, K.; Battle, A.

10.1101/2024.01.20.576447 — genomics — Posted on 2024-01-23

1333 Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states

Balasubramanian, R.; Kizhatil, K.; Li, T.; Tolman, N.; Bhandari, A.; Clark, G.; Bupp-Chickering, V.; Kelly, R. A.; Zhou, S.; Peregrin, J.; Simon, M.; Montgomery, C.; Stamer, W. D.; Qian, J.; John, S.

10.1101/2023.08.31.555823 — genomics — Posted on 2024-01-23

1334 Randomizing the human genome by engineering recombination between repeat elements

Koeppel, J.; Ferreira, R.; Vanderstichele, T.; Riedmayr, L. M.; Peets, E. M.; Girling, G.; Weller, J.; Liberante, F. G.; Ellis, T.; Church, G. M.; Parts, L.

10.1101/2024.01.22.576745 — genomics — Posted on 2024-01-23

1335 Improving estimates of negative selection in human genome using CAPS

Gudkov, M.; Thibaut, L.; Giannoulatou, E.

10.1101/2024.01.23.576817 — genomics — Posted on 2024-01-24

1336 A high coverage Mesolithic aurochs genome and effective leveraging of ancient cattle genomes using whole genome imputation.

Erven, J. A. M.; Scheu, A.; Verdugo, M. P.; Cassidy, L.; Chen, N.; Gehlen, B.; Street, M.; Madsen, O.; Mullin, V. E.

10.1101/2024.01.23.576850 — genomics — Posted on 2024-01-24

1337 A general model for two-locus assortative mating analysis and prediction

Smith, R. D.

10.1101/2024.01.20.576388 — genetics — Posted on 2024-01-23

1338 The variation landscape of CYP2D6 in a multi-ethnic Asian population

Maulana, Y.; Jimenez, R. T.; Twesigomwe, D.; Sani, L.; Irwanto, A.; Bertin, N.; Porta, M. G.

10.1101/2024.01.20.576401 — genetics — Posted on 2024-01-23

1339 Ecological specialization and local adaptation in sympatric sexual and asexual grass thrips species

Ghali, K.; van der Kooi, C. J.; Ramella, E.; Henry, M.; Schwander, T.

10.1101/2023.12.01.569600 — evolutionary biology — Posted on 2024-01-23

1340 Rewinding the ratchet: rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence

Decroly, T.; Vila, R.; Lohse, K.; Mackintosh, A.

10.1101/2024.01.20.576444 — evolutionary biology — Posted on 2024-01-23

1341 A multilocus perspective on the evolutionary dynamicsof multistrain pathogens

McLeod, D. V.; Bank, C. V.; Gandon, S.

10.1101/2023.10.27.564465 — evolutionary biology — Posted on 2024-01-23

1342 IntroUNET: identifying introgressed alleles via semantic segmentation

Ray, D. D.; Flagel, L.; Schrider, D. R.

10.1101/2023.02.07.527435 — evolutionary biology — Posted on 2024-01-23

1343 Altruism pays off in group-structured populations

Steiner, K. F.

10.1101/2024.01.20.575560 — evolutionary biology — Posted on 2024-01-23

1344 Evolution of human pair bonds as a consequence of male-biased mating sex ratios?

Nitschke, M. C.; Kim, P. S.; Hawkes, K.; Kumar, V.; Milliner, K. E.

10.1101/2024.01.22.576327 — evolutionary biology — Posted on 2024-01-23

1345 Changes in the cellular makeup of motor patterning circuits drive courtship song evolution in Drosophila

Ye, D.; Walsh, J. T.; Junker, I. P.; Ding, Y.

10.1101/2024.01.23.576861 — evolutionary biology — Posted on 2024-01-24

1346 Exploring functional connectivity in clinical and data-driven groups of preterm and term adults

Hadaya, L.; Vasa, F.; Dimitrakopoulou, K.; Saqi, M.; Shergill, S. S.; Edwards, D.; Batalle, D.; Leech, R.; Nosarti, C.

10.1101/2024.01.22.576651 — developmental biology — Posted on 2024-01-24

1347 Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

Yan, X.; Kuster, D.; Mohanty, P.; Nijssen, J.; Pombo-Garcia, K.; Rizuan, A.; Franzmann, T. M.; Sergeeva, A.; dos Passos, P. M.; George, L.; Wang, S.-H.; Shenoy, J.; Danielson, H. L.; Honigmann, A.; Ayala, Y. M.; Fawzi, N. L.; Mittal, J.; Alberti, S.; Hyman, A. A.

10.1101/2024.01.23.576837 — cell biology — Posted on 2024-01-24

1348 Extremely oligotrophic and complex carbon degrading microaerobic bacteria from Arabian Sea oxygen minimum zone sediments

Sarkar, J.; Mondal, M.; Bhattacharya, S.; Dutta, S.; Chatterjee, S.; Mondal, N.; N, S.; Peketi, A.; Mazumdar, A.; Ghosh, W.

10.1101/2023.10.31.564988 — microbiology — Posted on 2024-01-24

1349 A specialized inhibitory function sharpens somatosensory hand representation and enhances the production and perception of fast multifinger movements in pianists

Hirano, M.; Kimoto, Y.; Shiotani, S.; Furuya, S.

10.1101/2024.01.23.576947 — neuroscience — Posted on 2024-01-24

1350 MSK1 expression in the GABAergic network and its relationship with striatal growth, BDNF-mediated MeCP2 phosphorylation and schizophrenia

Varela-Andres, N.; Cebrian-Leon, A.; Hernandez-del Cano, C.; Fernandez-del Campo, I. S.; Garcia-Losada, S.; Martin-Avila, N.; Arevalo, J. C.; Merchan, M.; Sanchez-Martin, M. A.; Deogracias, R.

10.1101/2024.01.23.576945 — neuroscience — Posted on 2024-01-24

1351 Predicting individual variations in mental effort-based decision-making using machine learning: Neurometabolic signature in the dorsomedial prefrontal cortex/dorsal anterior cingulate cortex

Barakat, A.; Clairis, N.; Brochard, J.; Xin, L.; Sandi, C.

10.1101/2024.01.23.576854 — neuroscience — Posted on 2024-01-24

1352 Signatures of internal feedback and trajectory control during goal-directed finger and whole-arm reaching movements

Chakrabhavi, N.; SKM, V.; Ghosal, A.; Murthy, A.

10.1101/2023.08.09.552575 — neuroscience — Posted on 2024-01-24

1353 Beyond microtubules: The cellular environment at the endoplasmic reticulum attracts proteins to the nucleus, enabling nuclear transport

Chae, S. J.; Kim, D. W.; Igoshin, O. A.; Lee, S.; Kim, J. K.

10.1101/2024.01.12.575351 — systems biology — Posted on 2024-01-24

1354 Bursts of coalescence within population pedigrees whenever big families occur

Diamantidis, D.; Fan, W. T.; Birkner, M.; Wakeley, J.

10.1101/2023.10.17.562743 — evolutionary biology — Posted on 2024-01-23

1355 Pulmonary primary oxysterol and bile acid synthesis as a predictor of outcomesin pulmonary arterial hypertension

Alotaibi, M.; Harvey, L. D.; Nichols, W.; Pauciulo, M. W.; Hemnes, A. R.; Long, T.; Watrous, J. D.; Begzati, A.; Tuomilehto, J.; Havulinna, A. S.; Niiranen, T.; Jousilahti, P.; Salomaa, V.; Bertero, T.; Kim, N. H.; Desai, A. A.; Malhotra, A.; Yuan, J. X.- J.; Cheng, S.; Chan, S. Y.; Jain, M.

10.1101/2024.01.20.576474 — systems biology — Posted on 2024-01-23

1356 Deep learning reveals the role of copy number variation in the genetic architecture of a highly polymorphic sexual trait

van der Bijl, W.; Shu, J.; Goberdhan, V. S.; Sherin, L.; Cortazar-Chinarro, M.; Corral-Lopez, A.; Mank, J. E.

10.1101/2023.09.29.560175 — evolutionary biology — Posted on 2024-01-23

1357 'Drifting' Buchnera genomes track the microevolutionary trajectories of their aphid hosts

Thia, J. A.; Zhan, D.; Robinson, K.; Umina, P. A.; Hoffmann, A. A.; Yang, Q.

10.1101/2023.11.17.567149 — evolutionary biology — Posted on 2024-01-23

1358 Turnover rates of human muscle proteins in vivo reported in fractional, mole and absolute units.

Stansfield, B.; Barrett, J.; Bennett, S.; Stead, C. A.; Pugh, J.; Shepherd, S.; Strauss, J.; Louis, J.; Close, G.; Lisboa, P.; Burniston, J. G.

10.1101/2024.01.21.576451 — systems biology — Posted on 2024-01-23

1359 Linear-regression-based algorithms can succeed at identifying microbial functional groups despite the nonlinearity of ecological function

Zhao, Y.; Cordero, O. X.; Tikhonov, M.

10.1101/2024.01.21.576558 — ecology — Posted on 2024-01-23

1360 KDM3A and KDM3B Maintain Naive Pluripotency Through the Regulation of Alternative Splicing

Dillingham, C. M.; Cormaty, H.; Morgan, E.; Tak, A. I.; Esgdaille, D.; Boutz, P.; Sridharan, R.

10.1101/2023.05.31.543088 — cell biology — Posted on 2024-01-23

1361 Molecular characterization, localization, and physiological roles of ITP and ITP-L in the mosquito, Aedes aegypti

Sajadi, F.; Paluzzi, J.-P. V.

10.1101/2024.01.21.576557 — physiology — Posted on 2024-01-23

1362 Redox-dependent formation of a viral amyloid and functional impact

Gondelaud, F.; Lalande, A.; Pesce, G.; Bignon, C.; Fourquet, P.; Ptchelkine, D.; Brouilly, N.; Lozach, P.-Y.; Gerlier, D.; Mathieu, C.; Longhi, S.

10.1101/2024.01.22.576663 — biochemistry — Posted on 2024-01-23

1363 On the robustness of species coexistence to environmental perturbations

DESALLAIS, M.; LOREAU, M.; ARNOLDI, J.-F.

10.1101/2024.01.21.575550 — ecology — Posted on 2024-01-23

1364 Malaria parasite resistance to azithromycin is not readily transmitted by mosquitoes

Buchanan, H. D.; McConville, R.; Yeoh, L. M.; Duffy, M. F.; Boddey, J. A.; McFadden, G. I.; Goodman, C. D.

10.1101/2023.11.10.566666 — molecular biology — Posted on 2024-01-23

1365 Odorant receptors for floral- and plant-derived volatiles in the yellow fever mosquito, Aedes aegypti (Diptera: Culicidae)

Pullmann-Lindsley, H.; Huff, R.; Boyi, J.; Pitts, J.

10.1101/2023.10.17.562234 — molecular biology — Posted on 2024-01-23

1366 Two paralogous PHD finger proteins participate inParamecium tetraurelia's natural genome editing

Häussermann, L.; Singh, A.; Swart, E. C.

10.1101/2024.01.23.576875 — molecular biology — Posted on 2024-01-23

1367 A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Chauvier, A.; Dandpat, S.; Romero, R.; Walter, N. G.

10.1101/2024.01.23.576946 — molecular biology — Posted on 2024-01-23

1368 Comparison of direct cDNA and PCR-cDNA Nanopore sequencing of Escherichia coli isolates

Rodger, G.; Lipworth, S.; Barrett, L.; Oakley, S.; Crook, D. W.; Eyre, D. W.; Stoesser, N.

10.1101/2024.01.23.576853 — molecular biology — Posted on 2024-01-23

1369 The conformational landscape of human transthyretin revealed by cryo-EM

Basanta, B.; Nugroho, K.; Yan, N. Y.; Kline, G. M.; Powers, E. T.; Tsai, F. J.; Wu, M.; Hansel-Harris, A.; Chen, J. S.; Forli, S.; Kelly, J. W.; Lander, G. C.

10.1101/2024.01.23.576879 — molecular biology — Posted on 2024-01-23

1370 Transcriptomic interplay between Acinetobacter baumannii, human macrophage and polymyxin

Kho, Z. Y.; Azad, M. A. K.; Zhu, Y.; Han, M.-L.; Zhou, Q.; Velkov, T.; Naderer, T.; Li, J.

10.1101/2024.01.23.576770 — microbiology — Posted on 2024-01-23

1371 Decoding Klebsiella pneumoniae in Poultry Chain: Unveiling Genetic Landscape, Antibiotic Resistance, and Biocide Tolerance in Non-Clinical Reservoirs

Mourao, J.; Magalhaes, M.; Ribeiro-Almeida, M.; Rebelo, A.; Novais, C.; Peixe, L. V.; Novais, A.; Antunes, P.

10.1101/2024.01.23.576544 — microbiology — Posted on 2024-01-23

1372 Mouse Adaptation of Human Inflammatory Bowel Diseases Microbiota Enhances Colonization Efficiency and Alters Microbiome Aggressiveness Depending on Recipient Colonic Inflammatory Environment

Gray, S. M.; Moss, A. D.; Herzog, J.; Kashiwagi, S.; Liu, B.; Young, J. B.; Sun, S.; Bhatt, A. P.; Fodor, A.; Sartor, R. B.

10.1101/2024.01.23.576862 — microbiology — Posted on 2024-01-23

1373 Discovery and engineering of the antibody response against a prominent skin commensal

Bousbaine, D. A.; Bauman, K.; Chen, Y. E.; Yu, V.; Lalgudi, P.; Naziripour, A.; Veinbachs, A.; Phung, J.; Nguyen, T.; Swenson, M.; Lee, E.; Dimas, A.; Jain, S.; Meng, X.; Pham, T.; Zhao, A.; Barkal, L. J.; Gribonika, I.; Van Rompay, K. K. A.; Belkaid, Y.; Barnes, C. O.; Fischbach, M. A.

10.1101/2024.01.23.576900 — microbiology — Posted on 2024-01-23

1374 Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome

Lopez-Beltran, A.; Botelho, J.; Iranzo, J.

10.1101/2024.01.23.576851 — microbiology — Posted on 2024-01-23

1375 Establishing a straight-forward I-SceI mediated recombination one plasmid system for efficient genome editing in P. putida KT2440

Meng, H.; Koebbing, S.; Blank, L. M.

10.1101/2024.01.23.576838 — microbiology — Posted on 2024-01-23

1376 A marine sponge-associated mycobacterium closely related to Mycobacterium tuberculosis

Pidot, S. J.; Klatt, S.; Ates, L. S.; Frigui, W.; Sayes, F.; Majlessi, L.; Izumi, H.; Monk, I. R.; Porter, J. L.; Bennett-Wood, V.; Seemann, T.; Otter, A.; Taiaroa, G.; Cook, G. M.; West, N.; Tobias, N. J.; Fuerst, J. A.; Stutz, M. D.; Pelligrini, M.; McConville, M.; Brosch, R.; Stinear, T. P.; Stinear, T. P.

10.1101/2024.01.23.576949 — microbiology — Posted on 2024-01-23

1377 Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

Voss, W. N.; Mallory, M. A.; Byrne, P. O.; Marchioni, J. M.; Knudson, S. A.; Powers, J. M.; Leist, S. R.; Dadonaite, B.; Townsend, D. R.; Kain, J.; Huang, Y.; Satterwhite, E.; Castillo, I. N.; Mattocks, M.; Paresi, C.; Munt, J. E.; Scobey, T.; Seeger, A.; Premkumar, L.; Bloom, J. D.; Georgiou, G.; McLellan, J. S.; Baric, R. S.; Lavinder, J. J.; Ippolito, G. C.

10.1101/2024.01.22.576742 — immunology — Posted on 2024-01-23

1378 Objects, faces, and spaces: Organizational principles of visual object perception as evidenced by individual differences in behavior

Sigurdardottir, H. M.; Olafsdottir, I. M.

10.1101/2023.10.01.560383 — neuroscience — Posted on 2024-01-23

1379 Diurnal rhythmicity in salivary effector expression and metabolism shapes aphid performance on wheat plants

Han, J.; Kunk, D.; Cui, M.; Goldstein, Y.; Tzin, V.; Nalam, V. J.

10.1101/2024.01.20.576473 — systems biology — Posted on 2024-01-23

1380 Liebig's law of the minimum in the TGF-β/SMAD pathway

Li, Y.; Deng, D.; Höfer, C. T.; Kim, J.; Heo, W. D.; Xu, Q.; Liu, X.; Zi, Z.

10.1101/2023.07.10.548398 — systems biology — Posted on 2024-01-23

1381 A CANCER PERSISTENT DNA REPAIR CIRCUIT DRIVEN BY MDM2, MDM4 (MDMX), AND MUTANT P53 FOR RECRUITMENT OF MDC1 AND 53BP1 TO CHROMATIN

Ellison, V.; Polotskaia, A.; Leybengrub, P.; Qiu, W.; Lee, R.; Hendrickson, R. C.; Hu, W.; Bargonetti, J.

10.1101/2024.01.20.576487 — cancer biology — Posted on 2024-01-23

1382 DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity

Ryder, B. D.; Ustyantseva, E.; Boyer, D. R.; Mendoza-Oliva, A.; Kuska, M.; Wydorski, P. M.; Macierzynska, P.; Morgan, N.; Sawaya, M. R.; Diamond, M. I.; Kampinga, H. H.; Joachimiak, L.

10.1101/2023.03.06.531355 — biophysics — Posted on 2024-01-23

1383 Exact global alignment using A* with chaining seed heuristic and match pruning

Groot Koerkamp, R.; Ivanov, P.

10.1101/2022.09.19.508631 — bioinformatics — Posted on 2024-01-23

1384 Graph attention-based fusion of pathology images and gene expression for prediction of cancer survival

Zheng, Y.; Conrad, R. D.; Green, E. J.; Burks, E. J.; Betke, M.; Beane, J. E.; Kolachalama, V. B.

10.1101/2023.10.26.564236 — bioinformatics — Posted on 2024-01-23

1385 A Variational Graph Partitioning Approach to Modeling Protein Liquid-liquid Phase Separation

Wang, G.; Warrell, J.; Zheng, S.; Gerstein, M.

10.1101/2024.01.20.576375 — bioinformatics — Posted on 2024-01-23

1386 Self-inspired learning to denoise for live-cell super-resolution microscopy

Qu, L.; Zhao, S.; Huang, Y.; Ye, X.; Wang, K.; Liu, Y.; Liu, X.; Mao, H.; Hu, G.; Chen, W.; Guo, C.; He, J.; Tan, J.; Li, H.; Chen, L.; Zhao, W.

10.1101/2024.01.23.576521 — bioengineering — Posted on 2024-01-23

1387 Bioreversible anionic cloaking enables intracellular protein delivery with ionizable lipid nanoparticles

Alamgir, A.; Ghosal, S.; DeLisa, M.; Alabi, C. A.

10.1101/2024.01.20.576479 — bioengineering — Posted on 2024-01-23

1388 Elaboration of the Homer1 Recognition Landscape Reveals Incomplete Divergence of Paralogous EVH1 Domains

Singer, A.; Ramos, A.; Keating, A. E.

10.1101/2024.01.23.576863 — biochemistry — Posted on 2024-01-23

1389 Molecular mechanism of β-arrestin-2 interaction with phosphatidylinositol 4,5-bisphosphate

Kim, K.; Chung, K. Y.

10.1101/2024.01.22.576757 — biochemistry — Posted on 2024-01-23

1390 Dynamic Nature of Staphylococcus aureus Type I Signal Peptidases

Madsen, J. J.; Yu, W.

10.1101/2024.01.23.576923 — biochemistry — Posted on 2024-01-23

1391 Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4

Ekundayo, B.; Arullampalam, P.; Gerber, C.; Haemmerli, A.-F.; Guichard, S.; Boukenna, M.; Ross-Kaschitza, D.; Lochner, M.; Rougier, J.-S.; Stahlberg, H.; Abriel, H.; Ni, D.

10.1101/2024.01.22.576650 — biochemistry — Posted on 2024-01-23

1392 E41K Mutation Activates Brutons Tyrosine Kinase by Stabilizing an Inositol Hexakisphosphate Dependent Invisible Dimer

Das, R.; Chowdhury, S.; Chakraborty, M. P.; Roy, S.; Gangopadhyay, K.

10.1101/2024.01.22.576617 — biochemistry — Posted on 2024-01-23

1393 F420 reduction as a cellular driver for anaerobic ethanotrophy

Lemaire, O. N.; Wegener, G.; Wagner, T.

10.1101/2024.01.23.576903 — biochemistry — Posted on 2024-01-23

1394 Agriculturally developed areas reduce genetic connectivity for a keystone neotropical ungulate

BAPTISTA, M. S.; Keuroghlian, A.; Tambosi, L. R.; Cortes, M. C.; Maciel, F. G.; Cirino, D. W.; Shmaedecke, G.; Biondo, C.

10.1101/2024.01.22.576460 — ecology — Posted on 2024-01-23

1395 Pre-neuronal biomechanical filtering modulates and diversifies whole-hand tactile encoding

Tummala, N.; Reardon, G.; Dandu, B.; Shao, Y.; Saal, H. P.; Visell, Y.

10.1101/2023.11.10.565040 — neuroscience — Posted on 2024-01-23

1396 Moving Beyond Processing and Analysis-Related Variation in Neuroscience

Li, X.; Esper, N. B.; Ai, L.; Giavasis, S.; Jin, H.; Feczko, E.; Xu, T.; Clucas, J.; Franco, A.; Heinsfeld, A. S.; Adebimpe, A.; Vogelstein, J. T.; Yan, C.-G.; Esteban, O.; Poldrack, R. A.; Craddock, C.; Fair, D.; Satterthwaite, T.; Kiar, G.; Milham, M. P.

10.1101/2021.12.01.470790 — neuroscience — Posted on 2024-01-23

1397 Gene expression tradeoffs determine bacterial survival and adaptation to antibiotic stress

Kratz, J. C.; Banerjee, S.

10.1101/2024.01.20.576495 — systems biology — Posted on 2024-01-23

1398 The blast effector Pwl2 is a virulence factor that modifies the cellular localisation of host protein HIPP43 to suppress immunity.

Were, V.; Yan, X.; Foster, A.; Sklenar, J.; Langner, T.; Bentham, A.; Zdrzałek, R.; Ryder, L.; Kaimenyi, D.; Gomez De La Cruz, D.; Gentle, A.; Petit-Houdenot, Y.; Eseola, A. B.; Smoker, M.; Bautista, M. J.; Ma, W.; Kourelis, J.; Maclean, D.; Banfield, M. J.; Kamoun, S.; Menke, F. L. H.; Moscou, M. J.; Talbot, N. J.

10.1101/2024.01.20.576406 — plant biology — Posted on 2024-01-23

1399 Freshwater "microcroissants" shed light on a novel higher-level clade within Trebouxiophyceae and reveal the genus Chlorolobion as a trebouxiophyte

Barcyte, D.; Hodac, L.; Elias, M.

10.1101/2024.01.20.576396 — plant biology — Posted on 2024-01-23

1400 Genome-informed trophic classification and functional characterization of virulence proteins from the maize tar spot pathogen Phyllachora maydis

Rogers, A.; Jaiswal, N.; Roggenkamp, E.; Kim, H.-S.; MaCready, J.; Chilvers, M.; Scofield, S.; Iyer-Pascuzzi, A. S.; Helm, M.

10.1101/2024.01.22.576543 — plant biology — Posted on 2024-01-23

1401 XAPT and XLPT enzymes modify the glucuronic acid side chains of tissue-specific xylans in Arabidopsis and Eucalyptus

Yu, L.; Wilson, L. F. L.; Terrett, O. M.; Wurman-Rodrich, J.; Lyczakowski, J. J.; Yu, X.; Krogh, K. B. R. M.; Dupree, P.

10.1101/2024.01.23.575660 — plant biology — Posted on 2024-01-23

1402 An active light signalling pathway is necessary for ABA-induced inhibition of hypocotyl elongation.

Canibano, E.; Gomez-Soto, D.; Oliveros, J. C.; Bourbousse, C.; Fonseca, S.

10.1101/2024.01.20.576397 — plant biology — Posted on 2024-01-23

1403 Large library docking for cannabinoid-1 receptor agonists with reduced side effects

Tummino, T. A.; Iliopoulos-Tsoutsouvas, C.; Braz, J. M.; O'Brien, E. S.; Stein, R. M.; Craik, V.; Tran, N. K.; Ganapathy, S.; Liu, F.; Shiimura, Y.; Tong, F.; Ho, T. C.; Radchenko, D. S.; Moroz, Y. S.; Rosado, S. R.; Bhardwaj, K.; Benitez, J.; Liu, Y.; Kandasamy, H.; Normand, C.; Semache, M.; Sabbagh, L.; Glenn, I.; Irwin, J. J.; Kumar, K. K.; Makriyannis, A.; Basbaum, A. I.; Shoichet, B. K.

10.1101/2023.02.27.530254 — pharmacology and toxicology — Posted on 2024-01-23

1404 Exploring the potential of water channels for developing MRI reporters and sensors without the need for exogenous contrast agents

Chacko, A. N.; Miller, A. D. C.; Dhanabalan, K. M.; Mukherjee, A.

10.1101/2024.01.21.576580 — bioengineering — Posted on 2024-01-23

1405 Provisioning polyethylene glycol (PEG) to large herbivores in nutrient poor savannas can break food limitation

Schroder, B.; Schroder, N.-A. H.; Van Langevelde, F.; Prins, H. H. T.

10.1101/2024.01.20.576483 — ecology — Posted on 2024-01-23

1406 Thermal biology diversity of bee pollinators: taxonomic, phylogenetic and plant community-level correlates

Herrera, C. M.

10.1101/2023.11.27.568883 — ecology — Posted on 2024-01-23

1407 inDrops-2: a flexible, versatile and cost-efficient droplet microfluidics approach for high-throughput scRNA-seq of fresh and preserved clinical samples

Juzenas, S.; Kiseliovas, V.; Goda, K.; Zvirblyte, J.; Quintinal-Villalonga, A.; Nainys, J.; Mazutis, L.

10.1101/2023.09.26.559493 — molecular biology — Posted on 2024-01-23

1408 Molecular properties of RmlT, a wall teichoic acid rhamnosyltransferase that modulates Listeria monocytogenes virulence and antibiotic resistance

Monteiro, R.; Cereija, T. B.; Pombinho, R.; Sousa, S.; Morais Cabral, J.; Cabanes, D.

10.1101/2024.01.23.574818 — microbiology — Posted on 2024-01-23

1409 Chronic Toxoplasma gondii infection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain.

Uhrlaub, J. L.; McGovern, K. E.; Merritt, E. F.; Kuhns, M. S.; Koshy, A. A.; Nikolich, J. Z.

10.1101/2024.01.21.576564 — immunology — Posted on 2024-01-23

1410 Diverse competitor B cell responses to a germline-targeting priming immunogen in human Ig loci transgenic mice

Schiffner, T.; Palser, A.; Jardine, J. G.; Liguori, A.; Menis, S.; Raemisch, S.; Hu, X.; Kulp, D. W.; Wang, X.; Diedrich, J. K.; Groschel, B.; Kalyuzhniy, O.; Tingle, R.; Le, K.; Georgeson, E.; Adachi, Y.; Kubitz, M.; Landais, E.; Yates, J. R.; Paulson, J. C.; Sok, D.; Kellam, P.; Schief, W. R.

10.1101/2024.01.22.575410 — immunology — Posted on 2024-01-23

1411 Stepwise neofunctionalization of the NF-κB family member c-Rel during vertebrate evolution

Daly, A. E.; Chang, A. B.; Purbey, P.; Williams, K. J.; Yeh, G.; Li, S.; Pope, S. D.; Venkatesh, B.; Redelings, B. D.; Li, S.; Nguyen, K.; Rodriguez, J.; Jorgensen, K.; Siggers, T.; Chen, L.; Smale, S. T.

10.1101/2024.01.23.575293 — immunology — Posted on 2024-01-23

1412 Bypassing PELO-mediated ATPase activation of NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases

Wu, X.; Yang, Z.-H.; Zheng, Y.; Wu, J.; Han, J.

10.1101/2024.01.20.576395 — immunology — Posted on 2024-01-23

1413 Long-term B cell memory emerges at uniform relative rates in the human immune response

Cvijovic, I.; Swift, M.; Quake, S. R.

10.1101/2023.11.27.568934 — immunology — Posted on 2024-01-23

1414 SPT6L, a newly discovered ancestral component of the plant RNA-directed DNA methylation pathway

Cermak, V.; Kaspar, T.; Fischer, L.

10.1101/2024.01.20.576478 — plant biology — Posted on 2024-01-23

1415 Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors

Grimsley, H. E.; Antczak, M.; McLaughlin, K.-M.; Nist, A.; Mernberger, M.; Stiewe, T.; Speidel, D.; Harper-Wynne, C.; Cox, K.; Cinatl, J.; Wass, M. N.; Garrett, M.; Michaelis, M.

10.1101/2024.01.20.576412 — cancer biology — Posted on 2024-01-23

1416 Multimodal CustOmics: A Unified and Interpretable Multi-Task Deep Learning Framework for Multimodal Integrative Data Analysis in Oncology

Benkirane, H.; Vakalopoulou, M.; Planchard, D.; Adam, J.; Olaussen, K.; Michiels, S.; Cournede, P.-H.

10.1101/2024.01.20.576363 — cancer biology — Posted on 2024-01-23

1417 Biologically-informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post-treatment glioblastoma

Wang, H.; Argenziano, M. G.; Yoon, H.; Boyett, D.; Save, A.; Petridis, P.; Savage, W.; Jackson, P.; Hawkins-Daarud, A.; Tran, N.; Hu, L.; Al-Dalahmah, O.; Bruce, J. N.; Grinband, J.; Swanson, K. R.; Canoll, P.; Li, J.

10.1101/2022.12.20.521086 — cancer biology — Posted on 2024-01-23

1418 Collagen mineralization decreases NK cell-mediated cytotoxicity of breast cancer cells via increased glycocalyx thickness

Park, S.; Choi, S.; Shimpi, A. A.; Estroff, L. A.; Fischbach, C.; Paszek, M. J.

10.1101/2024.01.20.576377 — cancer biology — Posted on 2024-01-23

1419 Lignin isolated by microwave-assisted acid-catalyzed solvolysis induced cell death on mammalian tumor cells by modulating apoptotic pathways

Kashimoto, R.; Ohgitani, E.; Makimura, Y.; Miyazaki, T.; Kimura, C.; Shin-Ya, M.; Nishimura, H.; Pezzotti, G.; Watanabe, T.; Mazda, O.

10.1101/2024.01.20.576161 — cancer biology — Posted on 2024-01-23

1420 Tirzepatide attenuates mammary tumor progression in diet-induced obese mice

Glenny, E. M.; Ho, A. N.; Kiesel, V. A.; Chen, F.; Gates, C. E.; Paules, E. M.; Xu, R.; Holt, C. A.; Hursting, S. D.

10.1101/2024.01.20.576484 — cancer biology — Posted on 2024-01-23

1421 Understanding and predicting ligand efficacy in the mu-opioid receptor through quantitative dynamical analysis of complex structures

Galdino, G. T.; Mailhot, O.; Najmanovich, R.

10.1101/2024.01.20.576427 — biophysics — Posted on 2024-01-23

1422 Studying self-assembly of norovirus capsid by a combination of in silico methods

Carvaillo, J.-C.; Tubiana, T.; Detchanamourtty, S.; Bressanelli, S.; Barroso da Silva, F. L.; Boulard, Y.

10.1101/2024.01.21.575142 — bioinformatics — Posted on 2024-01-23

1423 Identification of Family-Specific Features in Cas9 and Cas12 Proteins: A Machine Learning Approach Using Complete Protein Feature Spectrum

Madugula, S. S.; Pujar, P.; Nammi, B.; Wang, S.; Jayasinghe-Arachchige, V.; Pham, T.; Mashburn, D.; Artiles, M.; Liu, J.

10.1101/2024.01.22.576286 — bioinformatics — Posted on 2024-01-23

1424 iVirP: An integrative, efficient, and user-friendly pipeline to annotate viral contigs from raw reads of metagenome or VLP sequencing

Li, B.; Jiao, X.; Liang, G.

10.1101/2024.01.21.576577 — bioinformatics — Posted on 2024-01-23

1425 STAR+WASP reduces reference bias in the allele-specific mapping of RNA-seq reads

Asiimwe, R.; Dobin, A.

10.1101/2024.01.21.576391 — bioinformatics — Posted on 2024-01-23

1426 Discovery of regulatory motifs associated with human insulator sites reveals the role of directional bias in insulator function

Osato, N.; Hamada, M.

10.1101/2024.01.20.573595 — bioinformatics — Posted on 2024-01-23

1427 The effect of the size of gold nanoparticle contrast agents on CT imaging of the gastrointestinal tract and inflammatory bowel disease

Rosario-Berrios, D. N.; Pang, A.; Liu, L.; Maidment, P. S. N.; Kim, J.; Yoon, S.; Nieves, L. M.; Mossburg, K.; Adezio, A.; Noel, P.; Lennon, E. M.; Cormode, D. P.

10.1101/2024.01.20.576354 — bioengineering — Posted on 2024-01-23

1428 Engineering multivalent Fc display for FcγR blockade

Petrova, E.; Kiriako, G.; Rebetz, J.; Johansson, K.; Wennmalm, S.; Meijer, N. E. J.; Hällberg, B. M.; Andre, I.; Ambrosetti, E.; Semple, J. W.; Teixeira, A. I.

10.1101/2024.01.20.576357 — bioengineering — Posted on 2024-01-23

1429 Stronger evidence for relaxed selection than adaptive evolution in high-elevation animal mtDNA

Iverson, E. N. K.; Criswell, A.; Havird, J. C.

10.1101/2024.01.20.576402 — evolutionary biology — Posted on 2024-01-23

1430 Can overlooking "invisible landscapes" bias habitat selection estimation and population distribution projections?

Dejeante, R.; Lemaire-Patin, R.; Chamaille-Jammes, S.

10.1101/2024.01.20.576416 — ecology — Posted on 2024-01-23

1431 The unseen invaders: tracking phylogeographic dynamics and genetic diversity of cryptic Pomacea canaliculata and P. maculata (Golden Apple Snails) across Taiwan

Banerjee, P.; Dey, G.; Maity, J. P.; Stewart, K. A.; Sharma, R. K.; Chan, M. W. Y.; Lee, K. H.; Chen, C.-Y.

10.1101/2024.01.20.576472 — ecology — Posted on 2024-01-23

1432 Effects of mineral addition on the establishment of grazing lawns in a nutrient poor savanna

Schroder, B.; Schroder, N.-A. H.; Van Langevelde, F.; Prins, H. H. T.

10.1101/2024.01.20.576489 — ecology — Posted on 2024-01-23

1433 Walk This Way: Modeling Foraging Ant Dynamics in Multiple Food Source Environments

Hartman, S.; Ryan, S.; Karamched, B. R.

10.1101/2024.01.20.576461 — ecology — Posted on 2024-01-23

1434 Nutrient addition on grazing lawns and selection by free-roaming mammalian herbivores in a nutrient poor savanna

Schroder, B.; Schroder, N.-A. H.; Van Langevelde, F.; Prins, H. H. T.

10.1101/2024.01.20.576488 — ecology — Posted on 2024-01-23

1435 Differential growth and transcriptomic profile of stem cell-derived midbrain astrocytes

Li, Z.; Cardo, L. F.; Rokicki, M.; Monzon-Sandoval, J.; Volpato, V.; Wessely, F.; Webber, C.; Li, M.

10.1101/2024.01.22.575551 — developmental biology — Posted on 2024-01-23

1436 Cause and chondroprotective effects of prostaglandin E2 secretion during mesenchymal stromal cell chondrogenesis

Schmidt, S.; Klampfleuthner, F. A.; Renkawitz, T.; Diederichs, S.

10.1101/2024.01.20.576230 — cell biology — Posted on 2024-01-23

1437 The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner

Stock, A. J.; Gonzalez-Paredes, P.; Previato de Almeida, L.; Kosanke, S. D.; Chetlur, S.; Budde, H.; Wakenight, P.; Zwingman, T. A.; Rosen, A. B.; Allenspach, E.; Millen, K. J.; Buckner, J. H.; Rawlings, D. J.; Gorman, J. A.

10.1101/2024.01.20.576482 — immunology — Posted on 2024-01-23

1438 Development and optimization of a diluted whole blood ELISpot assay to test immune function

Ungaro, R. F.; Xu, J.; Kucaba, T. A.; Rao, M.; Brakenridge, S. C.; Efron, P. A.; Gould, R. W.; Hotchkiss, R. S.; Mazer, M. B.; McGonagill, P. W.; Moldawer, L. L.; Remy, K. E.; Turnbull, I. R.; Caldwell, C. C.; Badovinac, V. P.; Griffith, T. S.

10.1101/2024.01.20.576465 — immunology — Posted on 2024-01-23

1439 Fast inhibition slows and desynchronizes auditory efferent neuron activity

Fischl, M.; Pederson, A.; Voglewede, R.; Cheng, H.; Drew, J.; Torres Cadenas, L.; Weisz, C.

10.1101/2023.12.21.572886 — neuroscience — Posted on 2024-01-23

1440 CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state

Huijgens, P. T.; Heijkoop, R.; Vanderschuren, L. J. M. J.; Lesscher, H. M. B.; Snoeren, E. M. S.

10.1101/2023.09.17.558107 — neuroscience — Posted on 2024-01-23

1441 A novel and efficient Apple Latent Spherical Virus-based gene silencing method for functional genomic studies in Chenopodium quinoa

Melgar, A. E.; Palacios, M. B.; Martinez-Tosar, L. J.; Zelada, A. M.

10.1101/2024.01.20.576358 — plant biology — Posted on 2024-01-23

1442 The temporal evolution of cancer hallmarks

Gourmet, L.; Ramazzotti, D.; Mallick, P.; Walker-Samuel, S.; Zapata, L.

10.1101/2024.01.21.576566 — cancer biology — Posted on 2024-01-23

1443 Contribution of cellular macromolecules to the diffusion of a 40 nm particle in Escherichia coli

Losa, J.; Heinemann, M.

10.1101/2024.01.22.576611 — biophysics — Posted on 2024-01-23

1444 Self-organization of PIP3 signaling is controlled by the confinement, topology, and curvature of the cell membrane.

Erisis, S.; Hoerning, M.

10.1101/2024.01.20.576405 — biophysics — Posted on 2024-01-23

1445 Serotonin Promotes Vesicular Association and Fusion by Modifying Lipid Bilayers

Roy, D. S.; Gupta, A.; Vishvakarma, V.; Krupa, P.; Li, M. S.; Maiti, S.

10.1101/2024.01.20.576155 — biophysics — Posted on 2024-01-23

1446 ThirdPeak: A flexible tool designed for the robust analysis of two- and three-dimensional (single-molecule) tracking data.

Engstler, M.; Mueller, T.; Meiser, E.

10.1101/2024.01.23.576823 — biophysics — Posted on 2024-01-23

1447 Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation

Quintana-Feliciano, R.; Kottur, J.; Ni, M.; Ghosh, R.; Salas-Estrada, L.; Rechkoblit, O.; Filizola, M.; Fang, G.; Aggarwal, A.

10.1101/2024.01.20.576384 — biophysics — Posted on 2024-01-23

1448 Sifting Through the Noise: A Computational Pipeline for Accurate Prioritization of Protein- Protein Binding Candidates in High-Throughput Protein Libraries

Mondal, A.; Singh, B.; Felkner, R. H.; De Falco, A.; Swapna, G.; Montelione, G. T.; Roth, M.; Perez, A.

10.1101/2024.01.20.576374 — biophysics — Posted on 2024-01-23

1449 Multiple Sclerosis Stages and their Differentially Expressed Genes: A Bioinformatics Analysis

Alaya, F.; Baraket, G.; Adediran, D. A.; Cuttler, K.; Ajiboye, I.; Kivumbi, M. T.; Sitharam, N.; Awe, O. I.

10.1101/2024.01.20.576448 — bioinformatics — Posted on 2024-01-23

1450 DiffModeler: Large Macromolecular Structure Modeling in Low-Resolution Cryo-EM Maps Using Diffusion Model

Wang, X.; Zhu, H.; Terashi, G.; Taluja, M.; Kihara, D.

10.1101/2024.01.20.576370 — bioinformatics — Posted on 2024-01-23

1451 ARYANA-BS: Context-Aware Alignment of Bisulfite-Sequencing Reads

Nikaein, H.; Sharifi-Zarchi, A.; Afzal, A.; Ezzati, S.; Rasti, F.; Chitsaz, H.; Kunde-Ramamoorthy, G.

10.1101/2024.01.20.576080 — bioinformatics — Posted on 2024-01-23

1452 AFM-RL: Large Protein Complex Docking Using AlphaFold-Multimer and Reinforcement Learning

Aderinwale, T.; Jahandideh, R.; Zhang, Z.; Zhao, B.; Xiong, Y.; Kihara, D.

10.1101/2024.01.20.576386 — bioinformatics — Posted on 2024-01-23

1453 Genome-wide profiling of genetic variation at tandem repeat from long reads

Ziaei Jam, H.; Zook, J. M.; Javadzadeh, S.; Park, J.; Sehgal, A.; Gymrek, M.

10.1101/2024.01.20.576266 — bioinformatics — Posted on 2024-01-23

1454 MicroFisher: Fungal taxonomic classification for metatranscriptomic and metagenomic data using multiple short hypervariable markers

Wang, H.; Wu, S.; Zhang, K.; Chen, K.-H.; Vilgalys, R.; LIAO, H.

10.1101/2024.01.20.576350 — bioinformatics — Posted on 2024-01-23

1455 Quantification of local matrix deposition during muscle stem cell activation using engineered hydrogels

Duran, P.; Yang, B. A.; Plaster, E.; Eiken, M.; Loebel, C.; Aguilar, C. A.

10.1101/2024.01.20.576326 — bioengineering — Posted on 2024-01-23

1456 β-Cells as a Cell Factory for On-Demand Recombinant Protein Dosing: Harnessing the Neuroendocrine Cell Secretory Pathway for Controlled Release

Poon, A. S. Y.; Annes, J.; Thomson, E. A.; Lal, R. A.; Xu, H.; Lee, S.

10.1101/2024.01.20.576492 — bioengineering — Posted on 2024-01-23

1457 Black Soldier Fly Bioconversion to Cultivated Meat Media Components Using Blue Catfish Gut Microbiome

Timoneda, A.; Amirvaresi, A.; Ovissipour, R.

10.1101/2024.01.20.576372 — bioengineering — Posted on 2024-01-23

1458 Postmortem MRI of Tissue Frozen at Autopsy

Nair, G.; Sun, R.; Merkel, H.; Hoskin, K.; Bree, K.; Dodd, S.; Koretsky, A.

10.1101/2024.01.20.576456 — bioengineering — Posted on 2024-01-23

1459 Overcoming Pitfalls when Estimating Variation in Parental Care: A Simulation Study

Mundry, R.; Dal Pesco, F.; Aviles de Diego, A.; Fischer, J.

10.1101/2023.10.16.562548 — animal behavior and cognition — Posted on 2024-01-23

1460 Temperature-mediated dynamics: unraveling the impact of temperature on cuticular hydrocarbon profiles, mating behavior, and life history traits in three Drosophila species

Baleba, S. B. S.; Jiang, N.-J.; Hansson, B. S.

10.1101/2024.01.20.576429 — ecology — Posted on 2024-01-23

1461 Evaluation of the cross reactivity of neutralising antibody response in vaccinated human and convalescent hamster sera against SARS-CoV-2 variants up to and including JN.1 using an authentic virus neutralisation assay

Coombes, N. S.; Bewley, K. R.; Le Duff, Y.; Alami-Rahmouni, N.; Ryan, K. A.; Kempster, S.; Ferguson, D.; Davies, E. R.; Weldon, T. M.; Cross, E. S.; Smith, L.; Norris, C.; Rogers-Broadway, K. R.; Lewandowski, K.; Treagus, S.; Pullan, S. T.; Hallis, B.; Charlton, S.; Hall, Y.; Funnell, S. G. P.

10.1101/2023.10.21.563398 — cell biology — Posted on 2024-01-23

1462 A Multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A.

Carrington, G.; Fatima, U.; Caramujo, I.; Lewis, T.; Casas-Mao, D.; Peckham, M.

10.1101/2024.01.18.576271 — cell biology — Posted on 2024-01-23

1463 Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have sub-minute half-lives

Jenniches, L.; Michaux, C.; Popella, L.; Reichardt, S.; Vogel, J.; Westermann, A. J.; Barquist, L.

10.1101/2023.06.15.545072 — microbiology — Posted on 2024-01-23

1464 Full resolution HLA and KIR genes annotation for human genome assemblies

Zhou, Y.; Song, L.; Li, H.

10.1101/2024.01.20.576452 — immunology — Posted on 2024-01-23

1465 Self-Supervised Transformer Model Training for a Sleep-EEG Foundation Model

Ogg, M.; Coon, W. G.

10.1101/2024.01.18.576245 — neuroscience — Posted on 2024-01-23

1466 Episodic long-term memory formation during slow-wave sleep

Schmidig, F. J.; Ruch, S.; Henke, K.

10.1101/2022.10.24.513503 — neuroscience — Posted on 2024-01-23

1467 Interpretable deep learning for deconvolutional analysis of neural signals

Tolooshams, B.; Matias, S.; Wu, H.; Temereanca, S.; Uchida, N.; Murthy, V. N.; Masset, P.; Ba, D.

10.1101/2024.01.05.574379 — neuroscience — Posted on 2024-01-23

1468 The combination of feedforward and feedback processing accounts for contextual effects in visual cortex

Di Santo, S.; Dipoppa, M.; Keller, A.; Roth, M.; Scanziani, M.; Miller, K. D.

10.1101/2022.05.27.493753 — neuroscience — Posted on 2024-01-23

1469 Injectable borax-loaded alginate hydrogels reduce muscle atrophy, modulate inflammation, and generate neuroprotection in the SOD1G93A mouse model of ALS via activation of the IGF-Akt-mTOR axis pathway.

Rodriguez-Romano, A.; Gonzalez-Valdivieso, J.; Moreno-Martinez, L.; Costa, J. F. V.; Osta, R.; Rico, P.

10.1101/2023.11.14.567052 — neuroscience — Posted on 2024-01-23

1470 Beta-cell adaptation to metabolic stresses requires prolactin receptor signaling

Lee, D.; Kahlon, R.; Kola-Ilesanmi, D.; Rahman, M.; Huang, C.

10.1101/2024.01.20.575603 — physiology — Posted on 2024-01-23

1471 Active site remodeling in IDH1 mutants drives distinct kinetic and potential resistance mechanisms

Mealka, M.; Sierra, N. A.; Matteo, D. A.; Albekioni, E.; Khoury, R.; Mai, T.; Conley, B. M.; Coleman, N. J.; Sabo, K. A.; Komives, E. A.; Bobkov, A. A.; Cooksy, A. L.; Silletti, S.; Schiffer, J. M.; Huxford, T.; Sohl, C. D.

10.1101/2024.01.10.574970 — biochemistry — Posted on 2024-01-23

1472 Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments

Wang, T.; Fu, Y.; Shuai, M.; Zheng, J.-S.; Zhu, L.; Chan, A. T.; Sun, Q.; Hu, F. B.; Weiss, S. T.; Liu, Y.-Y.

10.1101/2023.11.21.568102 — microbiology — Posted on 2024-01-23

1473 Structural determinants of co-translational protein complex assembly

Malik, S.; Venezian, J.; Lobov, A.; Heidenreich, M.; Garcia-Seisdedos, H.; Yeates, T. O.; Shiber, A.; Levy, E. D.

10.1101/2024.01.20.576408 — systems biology — Posted on 2024-01-23

1474 Joint-specific rheumatoid arthritis fibroblast-like synoviocyte regulation identified by integration of chromatin access and transcriptional activity

Choi, E.; Machado, C. R. L.; Okano, T.; Boyle, D.; Wang, W.; Firestein, G. S.

10.1101/2024.01.12.575379 — bioinformatics — Posted on 2024-01-23

1475 Range expansion is both slower and more variable with rapid evolution across a spatial gradient in temperature

Usui, T.; Angert, A. L.

10.1101/2023.09.14.557841 — ecology — Posted on 2024-01-23

1476 Glycolysis-Wnt signaling axis tunes developmental timing of embryo segmentation

Miyazawa, H.; Rada, J.; Sanchez, P. G. L.; Esposito, E.; Bunina, D.; Girardot, C.; Zaugg, J.; Aulehla, A.

10.1101/2024.01.22.576629 — developmental biology — Posted on 2024-01-23

1477 Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice

Bruter, A. V.; Varlamova, E. A.; Stavskaya, N. I.; Antysheva, Z. G.; Manskikh, V. N.; Tvorogova, A. V.; Korshunova, D. S.; Khamidullina, A. I.; Utkina, M. V.; Bogdanov, V. P.; Nikiforova, A. I.; Albert, E. A.; Maksimov, D. O.; Li, J.; Chen, M.; Shtil, A. A.; Roninson, I. B.; Mogila, V. A.; Silaeva, Y. Y.; Tatarskiy, V. V.

10.1101/2023.11.04.564913 — developmental biology — Posted on 2024-01-23

1478 Optogenetic generation of leader cells reveals a force-velocity relation for collective cell migration

Rossetti, L.; Grosser, S.; Abenza, J. F.; Valon, L.; Roca-Cusachs, P.; Alert, R.; Trepat, X.

10.1101/2024.01.23.576733 — cell biology — Posted on 2024-01-23

1479 Retinal metabolism: Evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs-cycle

Chen, Y.; Zizmare, L.; Calbiague, V.; Wang, L.; Yu, S.; Herberg, F. W.; Schmachtenberg, O.; Paquet-Durand, F.; Trautwein, C.

10.1101/2022.06.20.496788 — cell biology — Posted on 2024-01-23

1480 Reactivating Positive Personality Traits During Sleep Promotes Positive Self-Referential Processing

Yao, Z.; Xia, T.; Wei, J.; Zhang, Z.; Lin, X.; Zhang, D.; Qin, P.; Ma, Y.; Hu, X.

10.1101/2022.11.27.518064 — neuroscience — Posted on 2024-01-23

1481 Behaviorally irrelevant feature matching increases neural and behavioral working memory readout: Support for activity-silent working memory

Karabay, A.; Wolff, M. J.; Ruuskanen, V.; Akyurek, E. G.

10.1101/2023.09.12.557327 — neuroscience — Posted on 2024-01-23

1482 Bioengineering a plant NLR immune receptor with a robust binding interface towards a conserved fungal pathogen effector

Zdrzalek, R.; Xi, Y.; Langner, T.; Bentham, A. R.; Petit-Houdenot, Y.; De la Concepcion, J. C.; Harant, A.; Shimizu, M.; Were, V.; Talbot, N. J.; Terauchi, R. J.; Kamoun, S.; Banfield, M. J.

10.1101/2024.01.20.576400 — plant biology — Posted on 2024-01-23

1483 Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29 and Fam21

Romano-Moreno, M.; Astorga-Simon, E. N.; Rojas, A. L.; Hierro, A.

10.1101/2024.01.22.576619 — biochemistry — Posted on 2024-01-23

1484 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease

Lobato-Moreno, S.; Yildiz, U.; Claringbould, A.; Servaas, N. H.; Vlachou, E. P.; Arnold, C.; Bauersachs, H. G.; Campos-Fornes, V.; Prummel, K. D.; Noh, K. M.; Marttinen, M.; Zaugg, J. B.

10.1101/2023.12.26.573253 — genomics — Posted on 2024-01-23

1485 A Multiomics, Spatiotemporal, and Single Cell Atlas for Mapping Cell-Type-Specific Dysregulation at the Maternal-Fetal Interface

Wang, C.; Zhou, Y.; Wang, Y.; Guha, T. K.; Luo, Z.; McIntyre, T. I.; Schwab, M. E.; Davidson, B. R.; Reeder, G. C.; Wong, R. J.; England, S.; Gonzalez, J. M.; Blelloch, R.; Combes, A. J.; Giudice, L. C.; Erlebacher, A.; MacKenzie, T. C.; Stevenson, D. K.; Shaw, G. M.; Snyder, M. P.; Fisher, S. J.; Winn, V. D.; Li, J.

10.1101/2024.01.18.576324 — genomics — Posted on 2024-01-23

1486 Synchronization of Human Circadian Genes Between in vivo and Cultured Blood Samples

Pritt, J.; Counts, J.; Campbell, M.; Reed, D.; Kraus, W.

10.1101/2024.01.20.576368 — genomics — Posted on 2024-01-23

1487 Epigenetic reprogramming driving successful and failed repair in acute kidney injury

Muto, Y.; Dixon, E. E.; Yoshimura, Y.; Ledru, N.; Kirita, Y.; Wu, H.; Humphreys, B. D.

10.1101/2024.01.20.576421 — genomics — Posted on 2024-01-23

1488 WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration

Coulter, A.; Cortes, V.; Theodore, C.; Cianciolo, R.; Korstanje, R.; Campellone, K.

10.1101/2024.01.22.576497 — cell biology — Posted on 2024-01-23

1489 Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

10.1101/2024.01.23.576837 — cell biology — Posted on 2024-01-23

1490 Myotubularin-related proteins regulate KRAS function by controlling plasma membrane levels of polyphosphoinositides and phosphatidylserine

Henkels, K.; Miller, T.; Naji, A.; van der Hoeven, R.; Liang, H.; Zhou, Y.; Hammond, G. R.; Hancock, J. F.; Cho, K.-J.

10.1101/2024.01.22.576612 — cell biology — Posted on 2024-01-23

1491 An evolutionary-conserved VPS34-PIKfyve-TRPML1-Myosin II axis regulates the speed of amoeboid cell migration

Dehio, P.; Michard, C.; Yam-Puc, J. C.; Marti i Lindez, A.-A.; Fabre, L.; Schaefer, T.; Wymann, M. P.; Okkenhaug, K.; Soldati, T.; Mehling, M.; Hess, C.

10.1101/2024.01.22.575998 — cell biology — Posted on 2024-01-23

1492 Bleomycin induced EBV-specific gastric epithelial cell death is enhanced by LMP2A

Wai, A. P.; Wadi, A. F.; Liu, Y.; Zolzaya, T.; Okada, S.; Iizasa, H.; Yoshiyama, H.

10.1101/2024.01.23.576907 — microbiology — Posted on 2024-01-23

1493 Causal Role of the Frontal Eye Field in Attention-induced Ocular Dominance Plasticity

Song, F.; Dong, X.; Zhao, J.; Wang, J.; Sang, X.; He, X.; Bao, M.

10.1101/2023.10.10.561439 — neuroscience — Posted on 2024-01-23

1494 Chaperone quality control in liquid-phase separated organelles

Scheidt, T.; Lemke, E. A.

10.1101/2024.01.23.576883 — biophysics — Posted on 2024-01-23

1495 Relaxed purifying selection is associated with an accumulation of transposable elements in flies

Merel, V.; Tricou, T.; Burlet, N.; Haudry, A. V.

10.1101/2024.01.23.576885 — evolutionary biology — Posted on 2024-01-23

1496 Satb2 regulates pyramidal cell differentiation and the development of feedforward inhibitory circuits in CA1 hippocampus

Hanson, M. A.; Bibi, N.; Safa, A.; Nagarajan, D.; Marshall, A. H.; Johantges, A. C.; Wester, J. C.

10.1101/2024.01.23.576902 — neuroscience — Posted on 2024-01-23

1497 Epigenetic reprogramming driving successful and failed repair in acute kidney injury

Muto, Y.; Dixon, E. E.; Yoshimura, Y.; Ledru, N.; Kirita, Y.; Wu, H.; Humphreys, B. D.

10.1101/2024.01.20.576421 — genomics — Posted on 2024-01-23

1498 Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment

Xu, Q.-Y.; Wang, Y.-J.; He, Y.; Zheng, X.-Q.; Tong, M.-L.; Lin, Y.; Yang, T.-C.

10.1101/2024.01.23.576898 — neuroscience — Posted on 2024-01-23

1499 Posture-dependent modulation of marmoset cortical motor maps detected via rapid multichannel epidural stimulation

Takemi, M.; Tia, B.; Kosugi, A.; Castagnola, E.; Ansaldo, A.; Ricci, D.; Fadiga, L.; Ushiba, J.; Iriki, A.

10.1101/2024.01.23.576825 — neuroscience — Posted on 2024-01-23

1500 Temporal Dynamics of Brain Mediation in Predictive Cue-induced Pain Modulation

Gim, S.; Hong, S.-J.; Losin, E. A. R.; Woo, C.-W.

10.1101/2024.01.23.576786 — neuroscience — Posted on 2024-01-23

1501 Transcranial Photobiomodulation on the Left Prefrontal Cortex Enhances Mandarin Chinese L1 and L2 Complex Sentence Processing Performances

Yang, M.; Liu, Y.; Yue, Z.; Yang, G.; Jiang, X.; Cai, Y.; Zhang, Y.; Yang, X.; Li, D.; Chen, L.

10.1101/2024.01.22.576680 — neuroscience — Posted on 2024-01-23

1502 Encoding of task regularities links grid-like signals to human timing behavior

Polti, I.; Nau, M.; Kaplan, R.; van Wassenhove, V.; Doeller, C. F.

10.1101/2024.01.23.576694 — neuroscience — Posted on 2024-01-23

1503 Effects of D3-preferring agonist PD 128907 on compulsive behaviour and decision making as assessed by the 5C-CPT

Abdulkader, S. P.; Gigg, J.

10.1101/2024.01.22.576339 — animal behavior and cognition — Posted on 2024-01-23

1504 A neural correlate of learning fails to predict foraging efficiency in Bombus terrestris.

Pasquier, G.; Pull, C. D.; Ott, S. R.; Leadbeater, E.

10.1101/2024.01.23.576659 — animal behavior and cognition — Posted on 2024-01-23

1505 Ecological niche divergence or ecological niche partitioning in a widespread Neotropical bird lineage

Cooper, J. C.

10.1101/2024.01.18.576294 — evolutionary biology — Posted on 2024-01-23

1506 Preliminary Survey of Fungal Communities Across a Plastics/No Plastics Transition on an Oregon Beach

Cullings, K. W.; Arterbury, K. B.; Arterbury, R.

10.1101/2024.01.18.576272 — ecology — Posted on 2024-01-23

1507 The choroid plexus maintains ventricle volume and adult subventricular zone neuroblast pool, which facilitates post-stroke neurogenesis

Taranov, A.; Bedolla, A.; Iwasawa, E.; Brown, F. N.; Baumgartner, S.; Levoy, J.; Fugate, E. M.; Crone, S. A.; Goto, J.; Luo, Y.

10.1101/2024.01.22.575277 — neuroscience — Posted on 2024-01-23

1508 Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory

Chung, M.; Imanaka, K.; Huang, Z.; Watarai, A.; Wang, M.-Y.; Tao, K.; Ejima, H.; Aida, T.; Feng, G.; Okuyama, T.

10.1101/2024.01.22.576000 — neuroscience — Posted on 2024-01-23

1509 TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD

Bryce-Smith, S.; Brown, A.-L.; Mehta, P. R.; Mattedi, F.; Mikheenko, A.; Barattucci, S.; Zanovello, M.; Dattilo, D.; Yome, M.; Hill, S. E.; Qi, Y. A.; Wilkins, O. G.; Sun, K.; Ryadnov, E.; Wan, Y.; NYGC ALS Consortium, ; Vargas, J. N. S.; Birsa, N.; Raj, T.; Humphrey, J.; Keuss, M.; Ward, M.; Secrier, M.; Fratta, P.

10.1101/2024.01.22.576625 — neuroscience — Posted on 2024-01-23

1510 Progressive engagement of SST+ interneurons via Elfn1 regulates the barrel-septa response identity in the somatosensory cortex of mice

Argunsah, A. O.; Stachniak, T. J.; Yang, J.-W.; Cai, L.; Kanatouris, G.; Karayannis, T.

10.1101/2024.01.23.576792 — neuroscience — Posted on 2024-01-23

1511 DEFICIENCY OF THE NUTRIENT SENSOR CPT1c IN SF1 NEURONS DISRUPTS THE ENDOCANNABINOID SYSTEM RESULTING IN COMPROMISED SATIETY AND FUEL SELECTION UPON FAT INTAKE

Fosch, A.; Pizarro, D. S.; Zagmutt, S.; Reguera, A. C.; Batalle, G.; Rodriguez-Garcia, M.; Garcia-Chica, J.; Freire-Agulleiro, O.; Miralpeix, C.; Zizzari, P.; Serra, D.; Herrero, L.; Lopez, M.; Cota, D.; Rodriguez-Rodriguez, R.; Casals, N.

10.1101/2024.01.23.576690 — neuroscience — Posted on 2024-01-23

1512 Traumatic brain injury enhances the intrinsic excitation and excitatory transmission of granule cells

Danielewicz, J.; Llamosas, N.; Dura, I.; Mateos, D. M.; Encinas, J. M.

10.1101/2024.01.23.576807 — neuroscience — Posted on 2024-01-23

1513 Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury

Zhao, Q.; Zhu, Y.; Ren, Y.; Zhao, L.; Zhao, J.; Yin, S.; Ni, H.; Zhu, R.; Cheng, L.; Xie, N.

10.1101/2024.01.23.576887 — neuroscience — Posted on 2024-01-23

1514 Chronic potentiation of metabotropic glutamate receptor 2 with a nanobody accelerates amyloidogenesis in Alzheimer's disease.

Lafon, P.-A.; Tsitokana, M. E.; Alenda, U.; Philibert, C. E.; Oosterlaken, M.; Cimadevila, M.; Monnic, J.; Roux, S.; Bessie, J.; Diem, S.; Vandermoere, F.; Prezeau, L.; Chames, P.; Kniazeff, J.; Claeysen, S.; Pin, J.-P.; Perrier, V.; Liu, J.; Rondard, P.

10.1101/2024.01.22.576777 — neuroscience — Posted on 2024-01-23

1515 Exploring social modulation: Microglia as a key mediator of individual immune response, plasticity and pathology in App-NL-G-F mouse model of Alzheimer's disease

Ehret, F.; Doludda, B. G.; Liu, H.; Nexhipi, S.; Huang, H.; Barde, W.; Rost, F.; Overall, R. W.; Dahl, A.; Schmidt, M. H.; Sieweke, M.; Kempermann, G.

10.1101/2024.01.23.576790 — neuroscience — Posted on 2024-01-23

1516 Sensory Input, Sex, and Function Shape Hypothalamic Cell Type Development

Kaplan, H. S.; Logeman, B. L.; Zhang, K.; Santiago, C.; Sohail, N.; Naumenko, S.; Ho Sui, S. J.; Ginty, D. D.; Ren, B.; Dulac, C.

10.1101/2024.01.23.576835 — neuroscience — Posted on 2024-01-23

1517 Embryonic origins of forebrain oligodendrocytes revisited by combinatorial genetic fate mapping

Cai, Y.; Zhao, Z.; Shi, M.; Zheng, M.; Gong, L.; He, M.

10.1101/2024.01.23.576886 — neuroscience — Posted on 2024-01-23

1518 Standardised Measurements for Monitoring and Comparing Multiphoton Microscope Systems

Lees, R. M.; Bianco, I. H.; Campbell, R. A. A.; Orlova, N.; Peterka, D. S.; Pichler, B.; Smith, S. L.; Yatsenko, D.; Yu, C.-H.; Packer, A. M.

10.1101/2024.01.23.576417 — neuroscience — Posted on 2024-01-23

1519 Taste cells expressing Ionotropic Receptor 94e reciprocally impact feeding and egg laying in Drosophila

Guillemin, J.; Li, V.; Davis, G.; Audette, K.; Li, J.; Jelen, M.; McDowell, S. A. T.; Slamani, S.; Kelliher, L.; Gordon, M. D.; Stanley, M.

10.1101/2024.01.23.576843 — neuroscience — Posted on 2024-01-23

1520 fNIRS Dataset During Complex Scene Analysis

Ning, M.; Duwadi, S.; Yucel, M. A.; Luhmann, A. V.; Boas, D. A.; Sen, K.

10.1101/2024.01.23.576715 — neuroscience — Posted on 2024-01-23

Carbonell, F.; McNicoll, C.; Zijdenbos, A. P.; Bedell, B. J.

10.1101/2024.01.23.576866 — neuroscience — Posted on 2024-01-23

1522 DIRT/μ - Automated extraction of root hair traits using combinatorial optimization

Pietrzyk, P.; Phan-Udom, N.; Chutoe, C.; Pingault, L.; Roy, A.; Libault, M.; Johns Saengwilai, P.; Bucksch, A.

10.1101/2024.01.18.576310 — plant biology — Posted on 2024-01-23

1523 PD-1 Targeted Antibody Discovery Using AI Protein Diffusion

Ford, C. T.

10.1101/2024.01.18.576323 — cancer biology — Posted on 2024-01-23

1524 Matched three-dimensional organoids and two-dimensional cell lines of melanoma brain metastases mirror response to targeted molecular therapy

Hicks, W. H.; Gattie, L. C.; Traylor, J. I.; Davar, D.; Najjar, Y. G.; Richardson, T. E.; McBrayer, S. K.; Abdullah, K. G.

10.1101/2024.01.18.576318 — cancer biology — Posted on 2024-01-23

1525 Mitotic waves in frog egg extracts: Transition from phase waves to trigger waves

Puls, O.; Ruiz-Reynes, D.; Tavella, F.; Jin, M.; Kim, Y.; Gelens, L.; Yang, Q.

10.1101/2024.01.18.576267 — biophysics — Posted on 2024-01-23

1526 Biologically Driven In Vivo Occlusion Design Provides a Reliable Experimental Glaucoma Model

Hong, E.; Tian, F.; Glynn, C.; Tsekov, S.; Huang, S.; Zhou, S.; He, Z.; Rao, S.; Wang, Q.

10.1101/2024.01.18.576306 — biophysics — Posted on 2024-01-23

1527 Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning

Roy, G.; Syed, R.; Lazaro, O.; Robertson, S.; McCabe, S. D.; Rodriguez, D.; Mawla, A. M.; Johnson, T. S.; Kalwat, M. A.

10.1101/2024.01.18.576260 — bioinformatics — Posted on 2024-01-23

1528 Genotype sampling for deep-learning assisted experimental mapping of fitness landscapes

Wagner, A.

10.1101/2024.01.18.576262 — bioinformatics — Posted on 2024-01-23

1529 Autoprot: Processing, Analysis and Visualization of Proteomics Data in Python

Bender, J.; Mühlhäuser, W. W. D.; Zimmermann, J. P.; Drepper, F.; Warscheid, B.

10.1101/2024.01.18.571429 — bioinformatics — Posted on 2024-01-23

1530 CHOIR improves significance-based detection of cell types and states from single-cell data

Petersen, C.; Mucke, L.; Corces, M. R.

10.1101/2024.01.18.576317 — bioinformatics — Posted on 2024-01-23

1531 Automated Synthesis of Wireframe DNA Nanotubes

Islas, P.; Platnich, C.; Gidi, Y.; Karimi, R.; Ginot, L.; Cosa, G.; Sleiman, H.

10.1101/2024.01.18.576297 — bioengineering — Posted on 2024-01-23

1532 Sand flies around Tona, an artificial water reservoir in Bucaramanga (Santander, Colombia): diversity, spatiotemporal frequency, and efficacy of four sampling methods

Rengifo Correa, L.; Castillo, R. M.; Cuadros-Martinez, J.; Galati, E. A. B.; Duque, J. E.

10.1101/2024.01.18.576224 — ecology — Posted on 2024-01-23

1533 Differential growth and transcriptomic profile of stem cell-derived midbrain astrocytes

Li, Z.; Cardo, L. F.; Rokicki, M.; Monzon-Sandoval, J.; Volpato, V.; Wessely, F.; Webber, C.; Li, M.

10.1101/2024.01.22.575551 — developmental biology — Posted on 2024-01-23

1534 Dispersion-free inertial focusing (DIF) for high-yield polydisperse micro-particles filtration and analysis

Lee, K. C. M.; Chung, B. M. F.; Siu, D. M. D.; Ho, S. C. K.; Ng, D. K. H.; Tsia, K. K.

10.1101/2024.01.20.576445 — cell biology — Posted on 2024-01-23

1535 circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

Okholm, T. L. H.; Kamstrup, A. B.; Nielsen, M. M.; Hollensen, A. K.; Graversgaard, M. L.; Sorensen, M. H.; Kristensen, L. S.; Vang, S.; Park, S. S.; Yeo, G. W.; Dyrskjot, L.; Kjems, J.; Pedersen, J. S.; Damgaard, C. K.

10.1101/2023.09.14.557527 — molecular biology — Posted on 2024-01-23

1536 Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythm and sleep

Sun, Y.; Shui, K.; Li, Q.; Liu, C.; Ni, J.; Jin, W.; Lu, J.; Zhang, L.

10.1101/2023.11.22.568359 — neuroscience — Posted on 2024-01-23

1537 Extracellular RNA induce neutrophil recruitment via endothelial TLR3 during venous thrombosis after vascular injury

Najem, M. Y.; Rys, R. N.; Laurance, S.; Bertin, F.-R.; Gourdou-Latyszenok, V.; Gourhant, L.; Le Gall, L.; Le Corre, R.; Couturaud, F.; Blostein, M.; Lemarie, C. A.

10.1101/2024.01.18.576322 — physiology — Posted on 2024-01-23

1538 CoSpred: Machine learning workflow to predict tandem mass spectrum in proteomics

Xue, L.; Tiwary, S.; Bordyuh, M.; Jean-Beltran, P. M.; Stanton, R. V.

10.1101/2024.01.18.576149 — bioinformatics — Posted on 2024-01-23

1539 Toward a unified theory of microbially mediated invasion

Martignoni, M. M.; Garnier, J. M.; Tyson, R. C.; Harris, K. D.; Kolodny, O.

10.1101/2024.01.18.576278 — ecology — Posted on 2024-01-23

1540 Impact of Mesotherapy with Sodium Deoxycholate on Liver: Metabolic- and Sex-Specific Insights in Swiss mice

Goncalves, L. F.; Rosa, B. R.; Ramos, I. T. T.; Feder, J. B.; Messina, J. R. M.; Barreira, R. M.; Torres, V. M.; Simoes, V. L.; Paes-de-Almeida, E. C.; Fernandes-Santos, C.

10.1101/2024.01.18.576283 — pathology — Posted on 2024-01-23

1541 3D Bioprinting of Human Neural Tissues with Functional Connectivity

Yan, Y.; Li, X.; Gao, Y.; Mathivanan, S.; Kong, L.; Tao, Y.; Dong, Y.; Li, X.; Bhattacharyya, A.; Zhao, X.; Zhang, S.-C.

10.1101/2024.01.18.576289 — bioengineering — Posted on 2024-01-23

1542 Migraine inhibitor olcegepant reduces weight loss and IL-6 release in SARS-CoV-2 infected older mice with neurological signs

Rahman, S. M.; Buchholz, D. W.; Imbiakha, B.; Jaeger, M. C.; Leach, J.; Osborn, R. M.; Birmingham, A. O.; Dewhurst, S.; Aguilar, H. C.; Luebke, A. E.

10.1101/2023.10.23.563669 — neuroscience — Posted on 2024-01-23

1543 WITHDRAWN: Behavioral sequences across multiple animal species in the wild share common structural features

Minasandra, P.; Grout, E. M.; Crofoot, M. C.; Demartsev, V.; Gersick, A. S.; Hirsch, B. T.; Holekamp, K. E.; Johnson-Ulrich, L.; Nayak, A.; Ortega, J.; Roch, M. A.; Strauss, E. D.; Strandburg-Peshkin, A.

10.1101/2024.01.20.576411 — animal behavior and cognition — Posted on 2024-01-23

1544 Molecular Cloning and Biochemical Characterisation of a Novel Acidic Laminarinase Derived from Jermuk Hot Spring Metagenome

Paloyan, A.; Karapetyan, M.; Grigoryan, H.; Kruger, A.; Christin Burkhardt, C.; Antranikian, G.

10.1101/2024.01.22.576621 — biochemistry — Posted on 2024-01-23

1545 Phenotypic screening of covalent compound libraries identifies chloromethyl ketone antibiotics and MiaA as a new target

Jin, Y.; Jana, S.; Abbasov, M.; Lin, H.

10.1101/2024.01.22.576576 — biochemistry — Posted on 2024-01-23

1546 Establishment of CRISPR/Cas9-based knock-in in a hemimetabolous insect: targeted gene tagging in the cricket Gryllus bimaculatus

Matsuoka, Y.; Nakamura, T.; Watanabe, T.; Barnett, A. A.; Tomonari, S.; Ylla, G.; Whittle, C.; Noji, S.; Mito, T.; Extavour, C. G.

10.1101/2021.05.10.441399 — developmental biology — Posted on 2024-01-23

1547 Salivary extracellular vesicles isolation methods impact the robustness of downstream biomarkers detection

Boulestreau, J.; Molina, L.; Ouedraogo, A.; Laramy, L.; Grich, I.; Van, T. N. N.; Molina, F.; Kahli, M.

10.1101/2024.01.23.576809 — molecular biology — Posted on 2024-01-23

1548 FicD Sensitizes Cellular Response to Glucose Fluctuations in Mouse Embryonic Fibroblasts

Gulen, B.; Kinch, L. N.; Servage, K. A.; Blevins, A.; Stewart, N. M.; Gray, H. F.; Casey, A. K.; Orth, K.

10.1101/2024.01.22.576705 — molecular biology — Posted on 2024-01-23

1549 Alternative translation initiation by ribosomal leaky scanning produces multiple isoforms of the Pif1 helicase

Lama-Diaz, T.; Blanco, M. G.

10.1101/2024.01.21.576553 — molecular biology — Posted on 2024-01-23

1550 Topological regulation of the estrogen transcriptional response by ZATT-mediated inhibition of TOP2B activity

Terron-Bautista, J.; Martinez-Sanchez, M. d. M.; Lopez-Hernandez, L.; Vadusevan, A. A.; Garcia-Dominguez, M.; Williams, R. S.; Aguilera, A.; Millan-Zambrano, G.; Cortes-Ledesma, F.

10.1101/2024.01.22.576640 — molecular biology — Posted on 2024-01-23

1551 EXO1-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.

Garcia-Rodriguez, N.; Dominguez-Perez, M. d. C.; Huertas, P.

10.1101/2024.01.22.576613 — molecular biology — Posted on 2024-01-23

1552 Gut environmental factors explain variations in the gut microbiome composition and metabolism within and between healthy adults

Prochazkova, N.; Laursen, M. F.; La Barbera, G.; Tsekitsidi, E.; Joergensen, M. S.; Rasmussen, M. A.; Raes, J.; Dragsted, L. O.; Licht, T. R.; Roager, H. M.

10.1101/2024.01.23.574598 — microbiology — Posted on 2024-01-23

1553 Intensive environmental sampling and whole genome sequence-based characterization of Listeria in small and medium sized dairy plants reveal opportunities for simplified and size-appropriate environmental monitoring strategies

Bolten, S.; Lott, T. T.; Ralyea, R. D.; Gianforte, A.; Trmcic, A.; Orsi, R. H.; Martin, N. H.; Wiedmann, M.

10.1101/2024.01.22.576548 — microbiology — Posted on 2024-01-23

1554 MetaIBS: large-scale amplicon-based meta analysis of irritable bowel syndrome

Carcy, S.; Ostner, J.; Tran, V.; Menden, M. P.; Muller, C. L.

10.1101/2024.01.22.575775 — microbiology — Posted on 2024-01-23

1555 Evaluating the Effects of Environmental Disturbances and Pesticide Mixtures on Soil Microbial Endpoints

Drocco, C.; Coors, A.; Devers, M.; Spor, A.; Martin, F.; Rouard, N.

10.1101/2024.01.22.576671 — microbiology — Posted on 2024-01-23

1556 Structure-Guided Mutagenesis Targeting Interactions between pp150 Tegument Protein and Small Capsid Protein Identify Five Lethal and Two Live Attenuated HCMV Mutants

Stevens, A. W.; Cruz-Cosme, R.; Armstrong, N.; Tang, Q.; Zhou, Z. H.

10.1101/2024.01.22.576707 — microbiology — Posted on 2024-01-23

1557 CD8+ T cell response promotes viral clearance and reduces chances of severe testicular damage in mouse models of long-term Zika virus infection of the testes.

Kroon Campos, R.; Liang, Y.; Azar, S. R.; Ly, J.; Neves Camargos, V.; Hager-Soto, E. E.; Eyzaguirre, E.; Sun, J.; Rossi, S. L.

10.1101/2024.01.22.575592 — microbiology — Posted on 2024-01-23

1558 Specificities and commonalities of the Planctomycetes plasmidome

Quinonero-Coronel, M. d. M.; Garcillan-Barcia, M. P.; Devos, D. P.

10.1101/2024.01.22.576637 — microbiology — Posted on 2024-01-23

1559 Interaction of adenylate cyclase CyaC with regulators Smc01817 and Clr of Sinorhizobium meliloti: cAMP as an ON/OFF trigger in sensor-regulator complexes?

Klein, R.; Wissig, J.; Kuellmer, K.; Unden, G.

10.1101/2024.01.22.576614 — microbiology — Posted on 2024-01-23

1560 Birth of new protein folds and functions in the virome

Nomburg, J.; Price, N.; Doudna, J. A.

10.1101/2024.01.22.576744 — microbiology — Posted on 2024-01-23

1561 Brain resident macrophages regulate sleep, with repopulated ones being unable to reestablish the original sleep circuits

Seifinejad, A.; Monaco, G.; Bandarabadi, M.; Haddar, M.; Wundt, S.; Wingert, V.; Hannibal, L.; Blank, T.; Tafti, M.; Prinz, M.

10.1101/2024.01.22.576653 — neuroscience — Posted on 2024-01-23

1562 Mechanism of chaperone coordination during cotranslational protein folding in bacteria

Roeselova, A.; Maslen, S. L.; Shivakumaraswamy, S.; Pellowe, G. A.; Howell, S.; Joshi, D.; Redmond, J.; Kjaer, S.; Skehel, M.; Balchin, D.

10.1101/2024.01.22.576655 — biochemistry — Posted on 2024-01-23

1563 SOX9-regulated matrix proteins predict poor outcomes in patients with COVID-19 and pulmonary fibrosis

Pearmain, L.; Jokl, E.; Simpson, K.; Birchall, L.; Ou, Y.; Lawless, C.; Simpson, A.; Mann, E.; Scott, N. A.; Shah, R.; Venkateswaran, R.; Stanel, S.; Hayton, C.; Rivera-Ortega, P.; Hansbro, P.; Hanley, N.; Blaikley, J. A.; Piper Hanley, K.

10.1101/2024.01.21.576509 — molecular biology — Posted on 2024-01-23

1564 High ionic strength vector formulations enhance gene transfer to airway epithelia

Cooney, A. L.; Loza, L. M.; Najdawi, K.; Brommel, C.; McCray, P. B.; Sinn, P. L.

10.1101/2024.01.22.576687 — molecular biology — Posted on 2024-01-23

1565 Atacama Clear for Complex 3D Imaging of Organs

de Silva, N.; Lacko, L.; Jamies, E. A.; Evans, T.; Hurtado, R.

10.1101/2024.01.22.576689 — molecular biology — Posted on 2024-01-23

1566 Reanalysis of published data can help to characterize neuronal death after Spinal Cord Injury

Ruiz Amezcua, P.; Ibanez Barranco, N.; Reigada, D.; Novillo, I.; Soto, A.; Barreda-Manso, M. A.; Munoz-Galdeano, T.; Maza, R. M.; Esteban, F. J.; Nieto-Diaz, M.

10.1101/2024.01.22.576608 — molecular biology — Posted on 2024-01-23

1567 Viral entry is a weak barrier to zoonosis

Dufloo, J.; Andreu-Moreno, I.; Valero-Rello, A.; Sanjuan, R.

10.1101/2024.01.22.576693 — microbiology — Posted on 2024-01-23

1568 An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens

Tran, S. L.; Lebreuilly, L.; Cormontagne, D.; Samson, S.; To, T. B.; Dervyn, R.; Griesshammer, A.; Zuluaga, J. d. l. C.; Maier, L.; Naas, T.; Mura, S.; Nicolas, J.; Rognan, D.; Andre, G.; Ramarao, n.

10.1101/2024.01.22.576688 — microbiology — Posted on 2024-01-23

1569 Critical analysis of polycyclic tetramate macrolactam biosynthetic cluster phylogeny and functional diversity

Harper, C. P.; Day, A.; Tsingos, M.; Ding, E.; Zeng, E.; Stumpf, S. D.; Qi, Y.; Robinson, A.; Greif, J.; Blodgett, J. A. V.

10.1101/2024.01.22.576670 — microbiology — Posted on 2024-01-23

1570 Genomic diversity of novel strains of mammalian gut microbiome derived Clostridium XIVa strains is driven by mobile genetic element acquisition

Kamat, M.; Ormsby, M. J.; Humphrey, S.; Thummler, K.; Lapsley, C.; Crouch, K.; Jukes, C.; Hulme, H.; Burchmore, R.; Meikle, L.; Pritchard, L.; Wall, D. M.

10.1101/2024.01.22.576618 — microbiology — Posted on 2024-01-23

1571 Giardia Antagonizes Beneficial Functions of Indigenous and Therapeutic Intestinal Bacteria during Malnutrition

Bhatt, A. P.; Arnold, J.; Awoniyi, M.; Sun, S.; Feijoli, V.; Quintela, P. H.; Walsh, K.; Ngobeni, R.; Hansen, B.; Gulati, A. S.; Carroll, I.; Azcarate-Peril, M. A.; Fodor, A.; Swann, J.; Bartelt, L.

10.1101/2024.01.22.575921 — microbiology — Posted on 2024-01-23

1572 Future Climate Scenarios Aggravate Health Risks of Soil Microbiome by Reshaping Resistome and Pathogenome

Zhang, Z.; Ju, F.

10.1101/2024.01.22.576767 — microbiology — Posted on 2024-01-23

1573 Temperature-dependent Spike-ACE2 interaction of Omicron subvariants is associated with viral transmission

Benlarbi, M.; Ding, S.; Belanger, E.; Tauzin, A.; Poujol, R.; Medjahed, H.; El Ferri, O.; Bo, Y.; Bourassa, C.; Hussin, J.; Fafard, J.; Pazgier, M.; Levade, I.; Abrams, C.; Cote, M.; Finzi, A.

10.1101/2024.01.20.576353 — microbiology — Posted on 2024-01-23

1574 Identification and classification of the genomes of novel Microviruses in a poultry slaughterhouse

Xie, K.; Lin, B.; Zhu, P.; Sun, X.; Liu, C.; Liu, G.; Cao, X.; Pan, J.; Qiu, S.; Yuan, X.; Liang, M.; Jiang, J.; Yuan, L.

10.1101/2024.01.22.576691 — microbiology — Posted on 2024-01-23

1575 Evolution of a bistable genetic system in fluctuating and non- fluctuating environments

Fernandez-Fernandez, R.; Olivenza, D. R.; Weyer, E.; Singh, A.; Casadesus, J.; Sanchez-Romero, M. A.

10.1101/2024.01.22.576666 — microbiology — Posted on 2024-01-23

1576 Lateral hypothalamic GABAergic neurons encode alcohol memories.

Alonso-Lozares, I.; Wilbers, P.; Teijsse, S.; Asperl, L.; van der Neut, C.; Schetters, D.; Van Mourik, Y.; McDonald, A. J.; Heistek, T. S.; Mansvelder, H.; De Vries, T. J.; Marchant, N. J.

10.1101/2023.11.16.567157 — neuroscience — Posted on 2024-01-23

1577 kallisto, bustools, and kb-python for quantifying bulk, single-cell, and single-nucleus RNA-seq

Sullivan, D. K.; Min, K. H.; Hjörleifsson, K. E.; Luebbert, L.; Holley, G.; Moses, L.; Gustafsson, J.; Bray, N. L.; Pimentel, H.; Booeshaghi, A. S.; Melsted, P.; Pachter, L.

10.1101/2023.11.21.568164 — bioinformatics — Posted on 2024-01-23

1578 READv2: Advanced and user-friendly detection of biological relatedness in archaeogenomics

Alacamlı, E.; Naidoo, T.; Aktürk, S.; Güler, M. N.; Mapelli, I.; Vural, K. B.; Somel, M.; Malmström, H.; Günther, T.

10.1101/2024.01.23.576660 — bioinformatics — Posted on 2024-01-23

1579 Effect of composting and storage on the microbiome and resistome of cattle manure from a commercial dairy farm in Poland

Zalewska, M.; Błazejewska, A.; Szadziul, M.; Ciuchcinski, K.; Popowska, M.

10.1101/2023.12.04.569838 — microbiology — Posted on 2024-01-23

1580 Attentional Engagement and Disengagement: Quantifying Attentional Shifts Utilizing the Steady State Visual Evoked Potentials

Eidelman-Rothman, M.; Reuveni, O.; Keil, A.; Kritzman, L.; Freche, D.; Okon-Singer, H.; Levit-Binnun, N.

10.1101/2023.10.21.563393 — neuroscience — Posted on 2024-01-23

1581 Multi-omic integration of microbiome data for identifying disease-associated modules

Muller, E.; Shiryan, I.; Borenstein, E.

10.1101/2023.07.03.547607 — bioinformatics — Posted on 2024-01-23

1582 A dopaminergic memory circuit drives acute valence via multiple neurotransmitters

Mohammad, F.; Mai, Y.; Ho, J.; Zhang, X.; Ott, S.; Stewart, J. C.; Claridge-Chang, A.

10.1101/2022.11.23.517775 — animal behavior and cognition — Posted on 2024-01-23

1583 Multiplex generation and single cell analysis of structural variants in a mammalian genome

Pinglay, S.; Lalanne, J.-B.; Daza, R. M.; Koeppel, J.; Li, X.; Lee, D. S.; Shendure, J.

10.1101/2024.01.22.576756 — genomics — Posted on 2024-01-23

1584 Evolutionary trade-offs in dormancy phenology

Theo, C.; Dobson, F. S.; Habold, C.; Giroud, S.

10.1101/2023.07.20.549898 — evolutionary biology — Posted on 2024-01-23

1585 An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death

Terraza-Silvestre, E.; Villamuera, R.; Bandera-Linero, J.; Letek, M.; Ramon-Barros, C.; Moyano-Jimeno, C.; Ona-Sanchez, D.; Pimentel-Muinos, F. X.

10.1101/2024.01.21.576513 — cell biology — Posted on 2024-01-23

1586 Cryo-EM analysis on magnetic beads for scarce macromolecules in heterogeneous samples

Arimura, Y.; Konishi, H. A.; Funabiki, H.

10.1101/2024.01.21.576499 — molecular biology — Posted on 2024-01-23

1587 Subcellular localization of truncated MAGEL2 proteins: insight into the molecular pathology of Schaaf-Yang syndrome

Centeno-Pla, M.; Alcaide-Consuegra, E.; Gibson, S.; Prat-Planas, A.; Gutierrez-Avila, J. D.; Grinberg, D.; Urreizti, R.; Rabionet, R.; Balcells, S.

10.1101/2024.01.22.576607 — molecular biology — Posted on 2024-01-23

1588 Halofilins as Emerging Bactofilin Families of Archaeal Cell Shape Plasticity Orchestrators

Curtis, Z.; Escudeiro, P.; Mallon, J. L.; Leland, O.; Rados, T.; Dodge, A.; Andre, K.; Kwak, J.; Yun, K.; Pohlschroder, M.; Alva, V.; Bisson, A.

10.1101/2024.01.22.576759 — microbiology — Posted on 2024-01-23

1589 MerTK-dependent efferocytosis by monocytic-MDSCs mediates resolution of post-lung transplant injury

Leroy, V.; Manual Kollareth, D. J.; Tu, Z.; Valisno, J.; Woolet-Stockton, M. J.; Saha, B.; Emtiazjoo, A.; Rackauskas, M.; Moldawer, L.; Efron, P.; Cai, G.; Atkinson, C.; Upchurch, G. R.; Sharma, A. K.

10.1101/2024.01.18.576261 — immunology — Posted on 2024-01-23

1590 Nifuroxazide Suppresses PD-L1 Expression and Enhances the Efficacy of Radiotherapy in Hepatocellular Carcinoma

Zhao, T.; Wei, P.; Zhang, C.; Zhou, S.; Liang, L.; Guo, S.; Yin, Z.; Cheng, S.; Gan, Z.; Xia, Y.; Zhang, Y.; Guo, S.; Zhong, J.; Yang, Z.; Tu, F.; Wang, Q.; Bai, J.; Ren, F.; Feng, Z.; Jia, H.

10.1101/2023.09.03.556121 — immunology — Posted on 2024-01-23

1591 The FinnBrain Multimodal Neonatal Template and Atlas Collection: T1, T2, and DTI brain templates, and accompanying cortical and subcortical atlases

Tuulari, J. J.; Rosberg, A.; Pulli, E. P.; Hashempour, N.; Ukharova, E.; Lidauer, K.; Jolly, A.; Luotonen, S.; Audah, H. K.; Vartiainen, E.; Bano, W.; Suuronen, I.; Mariani Wigley, I. L. C.; Fonov, V.; Collins, D. L.; Merisaari, H.; Karlsson, L.; Karlsson, H.; Lewis, J. D.

10.1101/2024.01.18.576325 — neuroscience — Posted on 2024-01-23

1592 Precise 3D Localization of Intracerebral Implants with a simple Brain Clearing Method

Catanese, J.; Murakami, T.; Kenny, P. J.; Ibanez-Tallon, I.

10.1101/2023.12.22.573088 — neuroscience — Posted on 2024-01-23

1593 Dimensions of early life adversity are differentially associated with patterns of delayed and accelerated brain maturation

Beck, D.; Whitmore, L.; MacSweeney, N.; Brieant, A.; Karl, V.; de Lange, A.-M. G.; Westlye, L. T.; Mills, K. L.; Tamnes, C. K.

10.1101/2024.01.22.576780 — neuroscience — Posted on 2024-01-23

1594 Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex

Veeraraghavan, P.; Engmann, A. K.; Hatch, J. J.; Itoh, Y.; Nguyen, D.; Addison, T.; Macklis, J. D.

10.1101/2023.09.24.559186 — neuroscience — Posted on 2024-01-23

1595 Limited Diffusion of Scientific Knowledge Forecasts Collapse

Kang, D.; Danziger, R. S.; Rehman, J.; Evans, J. A.

10.1101/2023.04.15.536986 — scientific communication and education — Posted on 2024-01-23

1596 Regulation of interstitial fluid flow along adventitia of vasculature by heartbeat and respiration

Li, H.; Li, B.; Luo, W.; Qi, X.; Hao, Y.; Yang, C.; Li, W.; Li, J.; Hua, Z.; Guo, T.; Zheng, Z.; Yu, X.; Liu, L.; Zhao, J.; Li, T.; Huang, D.; Hu, J.; Li, Z.; Wang, F.; Li, H.; Ma, C.; Ji, F.

10.1101/2022.10.18.512678 — physiology — Posted on 2024-01-23

1597 Bridging the resolution-sectioning gap in stimulated emission depletion microscopy: theory and experiment

Belsley, M.; Soares-de-Oliveira, J.; Pereira, A. J.

10.1101/2024.01.18.576258 — biophysics — Posted on 2024-01-23

1598 Comparison of histological procedures and antigenicity of human post-mortem brains fixed with solutions used in gross anatomy laboratories

Frigon, E.-M.; Gerin-Lajoie, A.; Dadar, M.; Boire, D.; Maranzano, J.

10.1101/2024.01.18.576301 — neuroscience — Posted on 2024-01-22

1599 Learned response dynamics reflect stimulus timing and encode temporal expectation violations in superficial layers of mouse V1

Knudstrup, S. G.; Martinez Reyes, C.; Gavornik, J. P.

10.1101/2024.01.20.576433 — neuroscience — Posted on 2024-01-22

1600 A dynamic functional connectivity toolbox for multiverse analysis

Burkhardt, M.; Giessing, C.

10.1101/2024.01.21.576546 — neuroscience — Posted on 2024-01-22

1601 Resilience to Early Life Adversity Effects on Stress Reactivity by Postnatal Knockdown of 5-HT1A Autoreceptors

Dixon, R.; Malave, L.; Thompson, R.; Wu, S.; Sadik, N.; Anacker, C.

10.1101/2024.01.22.576344 — neuroscience — Posted on 2024-01-22

1602 Development of blood-cerebrospinal fluid barrier model expressing pharmaceutically important transporters.

Majerova, P.; Khiratkar, K.; James, K.; Olesova, D.; Vegh, J.; Kovac, A.

10.1101/2024.01.22.576616 — neuroscience — Posted on 2024-01-22

1603 Infralimbic activity during REM sleep facilitates fear extinction memory

Hong, J.; Choi, K.; Fuccillo, M. V.; Chung, S.; Weber, F.

10.1101/2024.01.20.576390 — neuroscience — Posted on 2024-01-22

1604 IMPDH2 filaments protect from neurodegeneration in AMPD2 deficiency

Flores-Mendez, M.; Ohl, L.; Roule, T.; Zhou, Y.; Tintos-Hernandez, J. A.; Walsh, K.; Ortiz-Gonzalez, X. R.; Akizu, N.

10.1101/2024.01.20.576443 — neuroscience — Posted on 2024-01-22

1605 Brain resident macrophages regulate sleep, with repopulated ones being unable to reestablish the original sleep circuits

Seifinejad, A.; Monaco, G.; Bandarabadi, M.; Haddar, M.; Wundt, S.; Wingert, V.; Hannibal, L.; Blank, T.; Tafti, M.; Prinz, M.

10.1101/2024.01.22.576653 — neuroscience — Posted on 2024-01-22

1606 Narcissus reflected: gray and white matter features joint contribution to the default mode network in predicting narcissistic personality traits

Jornkokgoud, K.; Baggio, T.; Bakiaj, R.; Wongupparaj, P.; Job, R.; Grecucci, A.

10.1101/2024.01.21.576578 — neuroscience — Posted on 2024-01-22

1607 Transcranial Focused Ultrasound Remotely Modulates Extrastriate Visual Cortex with Subregion Specificity

Yu, K.; Schmitt, S.; Ni, Y.; Crane, E. C.; Smith, M. A.; He, B.

10.1101/2024.01.20.576476 — neuroscience — Posted on 2024-01-22

1608 Impact of dendritic spine loss on excitability of hippocampal CA1 pyramidal neurons: a computational study of early Alzheimer disease

Tian, C.; Reyes, I.; Masurkar, A. V.

10.1101/2024.01.20.576500 — neuroscience — Posted on 2024-01-22

1609 Impact of maternal obesogenic diet on maternal and offspring microbiome development

Hasebe, K.; Kendig, M. D.; Kaakoush, N. O.; Tajaddini, A. S.; Westbrook, F.; Morris, M. J.

10.1101/2024.01.21.576569 — developmental biology — Posted on 2024-01-22

1610 Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure

Moshkelgosha, S.; Levy, L.; Safavi, S.; Karunagaran, S.; Wilson, G.; Renaud-Picard, B.; Madu, G.; Ramchandani, R.; Oliver, J.; Watanabe, T.; Bei, K. F.; Joe, B.; Li, Q.; Huszti, E.; Cheung, M.; Hedley, D.; Yeung, J.; Keshavjee, S.; Martinu, T.; Juvet, S.

10.1101/2023.12.19.572416 — immunology — Posted on 2024-01-22

1611 Claudin-4 modulates autophagy via SLC1A5/LAT1 as a tolerance mechanism for genomic instability in ovarian cancer.

R. Villagomez, F.; Lang, J.; Webb, P.; Neville, M.; Woodruff, E. R.; Bitler, B. G.

10.1101/2024.01.18.576263 — cancer biology — Posted on 2024-01-22

1612 The blobulator: a webtool for identification and visual exploration of hydrophobic modularity in protein sequences

Pitman, C.; Santiago-McRae, E.; Lohia, R.; Bassi, K.; Joseph, T. T.; Hansen, M. E. B.; Brannigan, G.

10.1101/2024.01.15.575761 — bioinformatics — Posted on 2024-01-22

1613 Feature selection followed by a residuals-based normalization simplifies and improves single-cell gene expression analysis

Singh, A.; Khiabanian, H.

10.1101/2023.03.02.530891 — bioinformatics — Posted on 2024-01-22

1614 The haplolethal gene wupA of Drosophila exhibits potential as a target for an X-poisoning gene drive

Lawler, C. D.; Parra Nunez, A. K.; Hernandes, N.; Bhide, S.; Lohrey, I.; Baxter, S.; Robin, C.

10.1101/2023.06.23.546292 — genetics — Posted on 2024-01-22

1615 Forget and Forgive: A Neurocognitive Mechanism for Increased Cooperation During Group Formation

Zajkowski, W. K.; Badman, R.; Haruno, M.; Akaishi, R.

10.1101/2024.01.13.572916 — neuroscience — Posted on 2024-01-22

1616 Obesity Facilitates Sex-Specific Improvement In Cognition And Neuronal Function In A Rat Model Of Alzheimer's Disease

Lai, A. Y.; Almanza, D. L. V.; Ribeiro, J. A.; Hill, M. E.; Mandrozos, M.; Koletar, M. M.; Stefanovic, B.; McLaurin, J.

10.1101/2024.01.11.575200 — neuroscience — Posted on 2024-01-22

1617 Oral Fentanyl Consumption Alters Sleep Rhythms, Promotes Avoidance Behaviors, Impairs Fear Extinction Learning, and Alters Basolateral Amygdala Physiology in Male and Female Mice

Downs, A. M.; Kmiec, G.; McElligott, Z. A.

10.1101/2023.11.28.569085 — neuroscience — Posted on 2024-01-22

1618 Metagenome profiling and containment estimation through abundance-corrected k-mer sketching with sylph

Shaw, J.; Yu, Y. W.

10.1101/2023.11.20.567879 — bioinformatics — Posted on 2024-01-22

1619 TrieDedup: A fast trie-based deduplication algorithm to handle ambiguous bases in high-throughput sequencing

Hu, J.; Luo, S.; Tian, M.; Ye, A. Y.

10.1101/2022.02.20.481170 — bioinformatics — Posted on 2024-01-22

1620 Positive selection drives cis-regulatory evolution across the threespine stickleback Y chromosome

Shaw, D. E.; Naftaly, A. S.; White, M. A.

10.1101/2022.11.03.515077 — genetics — Posted on 2024-01-22

1621 Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals

Crapart, C.; Scott, Z. C.; Konno, T.; Sharma, A.; Parutto, P.; Bailey, D. M.; Westrate, L. M.; Avezov, E.; Koslover, E. F.

10.1101/2023.06.23.546357 — cell biology — Posted on 2024-01-22

1622 Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

10.1101/2021.03.25.436925 — cell biology — Posted on 2024-01-22

1623 First-night effect reduces the beneficial effects of sleep on visual plasticity and modifies the underlying neurochemical processes

Tamaki, M.; Yamada, T.; Barnes-Diana, T.; Wang, Z.; Watanabe, T.; Watanabe, T.; Sasaki, Y.

10.1101/2024.01.21.576529 — neuroscience — Posted on 2024-01-22

1624 Lipid Dysregulation Unveil the Intricate Interplay of Lysosomal and Mitochondrial Changes in Frontotemporal Dementia with GRN Haploinsufficiency

Ondaro, J.; Zuniga-Elizari, J. L.; Zufiria, M.; Garciandia-Arcelus, M.; Zulaica, M.; Lafarga, M.; Riancho, J.; Holt, I. J.; Lopez de Munain, A.; Moreno, F.; Gil-Bea, F. J.; Gerenu, G.

10.1101/2024.01.22.576606 — neuroscience — Posted on 2024-01-22

1625 Physical Effort Pre-Crastination Determines Preference in an Isometric Task

Healy, C. M.; Ahmed, A. A.

10.1101/2024.01.20.576156 — neuroscience — Posted on 2024-01-22

1626 Neuronal Network Dynamics in the Posterodorsal Amygdala: Shaping Reproductive Hormone Pulsatility

Nechyporenko, K.; Voliotis, M.; Li, X. F.; Hollings, O.; Ivanova, D.; Walker, J. J.; O'Byrne, K. T.; Tsaneva-Atanasova, K.

10.1101/2024.01.21.574304 — neuroscience — Posted on 2024-01-22

1627 Disrupting fzd9b in zebrafish recapitulates stress- and anxiety-like behaviours associated with Williams syndrome

Torres-Perez, J. V.; Leggieri, A.; Mech, A.; Anagianni, S.; Havelange, W.; Brennan, C. H.

10.1101/2024.01.22.576596 — neuroscience — Posted on 2024-01-22

1628 Developmental emergence of first- and higher-order thalamic neuron molecular identities

Lo Giudice, Q.; Wagener, R. J.; Abe, P.; Frangeul, L.; Jabaudon, D.

10.1101/2024.01.22.576610 — neuroscience — Posted on 2024-01-22

1629 Dynamic transient brain states in preschoolers mirror parental report of behavior and emotion regulation

Toffoli, L.; Zdorovtsova, N.; Epihova, G.; Duma, G. M.; Del Popolo Cristaldi, F.; Pastore, M.; Astle, D. E.; Mento, G.

10.1101/2024.01.22.576699 — neuroscience — Posted on 2024-01-22

1630 Maternal n-3 enriched diet reprograms neurovascular transcriptome and blunts inflammation in neonate

Chumak, T.; Jullienne, A.; Ek, J.; Ardalan, M.; Svedin, P.; Quan, R.; Salehi, A.; Salari, S.; Obenaus, A.; Vexler, Z.; Mallard, C.

10.1101/2024.01.22.576634 — neuroscience — Posted on 2024-01-22

1631 Activity-Dependent Ectopic Spiking in Parvalbumin-Expressing Interneurons of the Neocortex

Theyel, B. B.; Stevenson, R. J.; Connors, B.

10.1101/2024.01.22.576676 — neuroscience — Posted on 2024-01-22

1632 Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress

Taylor, B. C.; Steinthal, L. H.; Dias, M.; Yalamanchili, H. K.; Ochsner, S. A.; Zapata, G. E.; Mehta, N. R.; McKenna, N. J.; Young, N. L.; Nuotio-Antar, A. M.

10.1101/2023.07.30.551059 — systems biology — Posted on 2024-01-22

1633 A Dynamical Systems Approach to Optimal Foraging

Chaturvedi, S.; ElGazzar, A.; Gerven, M. v.

10.1101/2024.01.20.576399 — animal behavior and cognition — Posted on 2024-01-22

1634 Perturbing nuclear glycosylation in the mouse preimplantation embryo slows down embryonic growth

Formichetti, S.; Chitnavis, U.; Sadowska, A.; Liu, N.; Boskovic, A.; Boulard, M.

10.1101/2024.01.22.576677 — developmental biology — Posted on 2024-01-22

1635 OCT4 is expressed in extraembryonic endoderm stem (XEN) cell progenitors during somatic cell reprogramming

Moauro, A.; Hickey, S. L.; Halbisen, M. A.; Parenti, A.; Ralston, A.

10.1101/2024.01.22.576724 — developmental biology — Posted on 2024-01-22

1636 Automated Cell Lineage Reconstruction using Label-Free 4D Microscopy

Waliman, M.; Johnson, R. L.; Natesan, G.; Tan, S.; Santella, A.; Hong, R. L.; Shah, P. K.

10.1101/2024.01.20.576449 — developmental biology — Posted on 2024-01-22

1637 Wnt signaling alters CTCF binding patterns and global chromatin structure

Nordin, A.; Chakraborty, C.; Jonasson, M.; Dano, O.; Zambanini, G.; Pagella, P.; Remeseiro, S.; Cantu, C.

10.1101/2024.01.22.576696 — developmental biology — Posted on 2024-01-22

1638 Differential growth and transcriptomic profile in stem cell-derived midbrain astrocytes

Li, Z.; Cardo, L. F.; Rokicki, M.; Monzon-Sandoval, J.; Volpato, V.; Wessely, F.; Webber, C.; Li, M.

10.1101/2024.01.22.575551 — developmental biology — Posted on 2024-01-22

1639 Glycolysis-Wnt signaling axis tunes developmental timing of embryo segmentation

Miyazawa, H.; Rada, J.; Sanchez, P. G. L.; Esposito, E.; Bunina, D.; Girardot, C.; Zaugg, J.; Aulehla, A.

10.1101/2024.01.22.576629 — developmental biology — Posted on 2024-01-22

1640 Tmc7 deficiency causes acrosome biogenesis defects and male infertility in mice

Wang, J.; Yin, Y.; Yang, L.; Qin, J.; Wang, Z.; Qiu, C.; Gao, Y.; Lu, G.; Gao, F.; Chen, Z.-J.; Zhang, X.; Liu, H.; Liu, Z.

10.1101/2024.01.18.576276 — developmental biology — Posted on 2024-01-22

1641 Subthalamic nucleus activity modifications prior to clinical impairment in a progressive model of Parkinson's disease

Bertrand, M.; Chabardes, S.; De Leiris, N.; Riboulet, G.; Bastin, J.; Piallat, B.

10.1101/2024.01.22.576571 — neuroscience — Posted on 2024-01-22

1642 Alpha phase-coding supports feature binding during working memory maintenance

Pagnotta, M. F.; Santo-Angles, A.; Temudo, A.; Barbosa, J.; Compte, A.; D'Esposito, M.; Sreenivasan, K. K.

10.1101/2024.01.21.576561 — neuroscience — Posted on 2024-01-22

1643 TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in ALS/FTD and related disorders

Arnold, F. J.; Cui, Y.; Michels, S.; Colwin, M. R.; Stockford, C.; Ye, W.; Tam, O. H.; Menon, S.; Situ, W. G.; Ehsani, K. C. K.; Howard, S.; Hammell, M. G.; Li, W.; La Spada, A. R.

10.1101/2024.01.22.576709 — neuroscience — Posted on 2024-01-22

1644 Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster.

Crawford, B. I.; Talley, M. J.; Russman, J.; Riddle, J.; Torres, S.; Williams, T.; Longworth, M. S.

10.1101/2024.01.22.576652 — neuroscience — Posted on 2024-01-22

Panwar, A.; Rentsendorj, A.; Jhun, M.; Cohen, R. M.; Cordner, R.; Gull, N.; Pechnick, R. N.; Duvall, G.; Mardiros, A.; Golchian, D.; Schubloom, H.; Jin, L.-W.; Van Dam, D.; Vermeiren, Y.; De Reu, H.; De Deyn, P. P.; Raskatov, J. A.; Black, K. L.; Irvin, D. K.; Williams, B. A.; Wheeler, C. J.

10.1101/2024.01.22.576704 — neuroscience — Posted on 2024-01-22

1646 NeuroCSF: an fMRI method to measure contrast sensitivity function in human visual cortex

Goulet, L. L.; Farivar, R. R.

10.1101/2024.01.22.576727 — neuroscience — Posted on 2024-01-22

1647 Multivariate Time-Lagged Multidimensional Pattern Connectivity (mvTL-MDPC) for EEG/MEG Functional Connectivity Analysis

Rahimi, S.; Jackson, R. L.; Hauk, O.

10.1101/2024.01.20.576221 — neuroscience — Posted on 2024-01-22

1648 Investigation of neural functional connectivity in thick acute mouse brain slices with novel multi-region 3D neural probe arrays

Smith, W. C.; Naumkina, Z.; Shin, H. G.; Chae, U. K.; Lee, S.; Park, J.-H.; Cho, Y. D.; Woo, J. W.; Kwon, S.-K.; Oh, S. J.; Nam, M.-H.; Kim, T. S.; Cho, I. J.

10.1101/2024.01.18.576320 — neuroscience — Posted on 2024-01-22

1649 A new insight into the role of CART peptide in serotonergic function and anxiety

Balasubramanian, N.; Wang, R.; Ismail, S.; Hartman, B.; Aboushaar, Z.; Marcinkiewcz, C. A.

10.1101/2024.01.22.576719 — neuroscience — Posted on 2024-01-22

1650 Concurrent processing of the prosodic hierarchy is supported by cortical entrainment and phase-amplitude coupling

Oderbolz, C.; Sauppe, S.; Meyer, M.

10.1101/2024.01.22.576636 — neuroscience — Posted on 2024-01-22

1651 Spreading depolarization causes reversible neuronal mitochondria fragmentation and swelling in healthy, normally perfused neocortex.

Sword, J.; Fomitcheva, I. V.; Kirov, S. A.

10.1101/2024.01.22.576364 — neuroscience — Posted on 2024-01-22

1652 A Vector System Encoding Histone H3 Mutants Facilitates Manipulations of the Neuronal Epigenome

Warren, S.; Xiong, S.; Robles, D.; Baizabal, J.-M.

10.1101/2024.01.18.576334 — neuroscience — Posted on 2024-01-22

1653 Selective attention modulates feature accumulation speed during perception and memory retrieval

Zhou, Y.; Zhang, L.; Dai, Y.; Peng, X.; Xue, G.

10.1101/2024.01.21.576506 — neuroscience — Posted on 2024-01-22

1654 Memory consolidation during rest forms shortcuts in a cognitive map

Shearer, C. M.; Rawson, A. B.; Barron, H. C.; O'Reilly, J. X.

10.1101/2024.01.22.576595 — neuroscience — Posted on 2024-01-22

1655 Obesity differentially effects the somatosensory cortex and striatum of TgF344-AD rats

Ahmed, M.; Lai, A. Y.; Hill, M. E.; Ribeiro, J. A.; Amiraslani, A.; McLaurin, J.

10.1101/2024.01.22.576454 — neuroscience — Posted on 2024-01-22

1656 Giant pyramidal neurons of the primary motor cortex express vasoactive intestinal polypeptide (VIP), a known marker of cortical interneurons

Teymornejad, S.; Worthy, K. H.; Rosa, M. G. P.; Atapour, N.

10.1101/2024.01.22.576584 — neuroscience — Posted on 2024-01-22

1657 Developmental order, fibre caliber, and vascularization predict tract-wise declines: Testing retrogenesis and physiological predictions in white matter aging

Robinson, T. D.; Chad, J. A.; Sun, Y. L.; Chang, P. T. H.; Chen, J. J.

10.1101/2024.01.20.576373 — neuroscience — Posted on 2024-01-22

Rideaux, R.

10.1101/2024.01.20.576485 — neuroscience — Posted on 2024-01-22

1659 Spontaneous oxycodone withdrawal disrupts sleep, circadian, and electrophysiological dynamics in rats

Gulledge, M.; Carlezon, W. A.; McHugh, R. K.; Prerau, M.; Chartoff, E.

10.1101/2024.01.21.576572 — neuroscience — Posted on 2024-01-22

1660 Explorations of using a convolutional neural network to understand brain activations during movie watching

Sohn, W.; Di, X.; Liang, Z.; Zhang, Z.; Biswal, B.

10.1101/2024.01.20.576341 — neuroscience — Posted on 2024-01-22

1661 Aging and injury drive neuronal senescence in the dorsal root ganglia

Donovan, L. J.; Brewer, C. L.; Bond, S. F.; Pena Lopez, A.; Hansen, L. H.; Jordan, C. E.; Gonzalez, O. C.; de Lecea, L.; Kauer, J. A.; Tawfik, V. L.

10.1101/2024.01.20.576299 — neuroscience — Posted on 2024-01-22

1662 Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics

Masharipov, R.; Knyazeva, I.; Korotkov, A.; Kireev, M.; Cherednichenko, D.

10.1101/2024.01.22.576622 — neuroscience — Posted on 2024-01-22

1663 Individual variability in neural representations of mind-wandering

Kucyi, A.; Anderson, N.; Bounyarith, T.; Braun, D.; Shareef-Trudeau, L.; Treves, I.; Braga, R. M.; Hsieh, P.-J.; Hung, S.-M.

10.1101/2024.01.20.576471 — neuroscience — Posted on 2024-01-22

1664 Sociality shapes the life histories of animals along the fast-slow continuum, but does not affect their senescence

Salguero-Gomez, R.

10.1101/2024.01.22.575897 — animal behavior and cognition — Posted on 2024-01-22

1665 Application of Elevated Atmospheric Pressure and Hypoxia Enhance Pluripotency and Stem Cell Differentiation

Pappalardo, Z.; Downie, B.; Adams, B. A.; Lim, J.

10.1101/2024.01.19.576329 — developmental biology — Posted on 2024-01-22

1666 The cost and payout of age on germline regeneration and sexual maturation in Platynereis dumerilii

Metzger, B. M.; Ozpolat, B. D.

10.1101/2024.01.22.576726 — developmental biology — Posted on 2024-01-22

1667 TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

Zeng, Y.; Lovchykova, A.; Aikyama, T.; Liu, C.; Guo, C.; Jawahar, V. M.; Sianto, O.; Calliari, A.; Prudencio, M.; Dickson, D. W.; Petrucelli, L.; Gitler, A. D.

10.1101/2024.01.22.575730 — neuroscience — Posted on 2024-01-22

1668 Decoding Cortical Circuits: Synaptic Signatures and Disease Vulnerabilities of Layer 5 Pyramidal Neuron Types

Marcassa, G.; Dascenco, D.; Lorente-Echeverria, B.; Vanderlinden, J.; Leysen, E.; Baltussen, L.; Howden, A. J. M.; de Wit, J.

10.1101/2024.01.22.576602 — neuroscience — Posted on 2024-01-22

1669 A One Health approach metagenomic study on the antimicrobial resistance traits of canine saliva

Toth, A. G.; Toth, D. L.; Remport, L.; Toth, I.; Nemeth, T.; Dubecz, A.; Patai, A. V.; Makrai, L.; Solymosi, N.

10.1101/2024.01.17.576087 — genomics — Posted on 2024-01-22

1670 Evolution of alternative reproductive systems in Bacillus stick insects

Lavanchy, G.; Brandt, A.; Bastardot, M.; Dumas, Z.; Labedan, M.; Massy, M.; Toubiana, W.; TranVan, P.; Luchetti, A.; Scali, V.; Mantovani, B.; Schwander, T.

10.1101/2023.07.31.550487 — evolutionary biology — Posted on 2024-01-22

1671 The information signature of diverging lineages

Moore, D. G.; Morales, M.; Biddy, A. R.; Walker, S. I.; Dolby, G. A.

10.1101/2021.08.30.458276 — evolutionary biology — Posted on 2024-01-22

1672 Chromosomal inversions and the demography of speciation in Drosophila montana and Drosophila flavomontana

Poikela, N.; Laetsch, D. R.; Hoikkala, V.; Lohse, K.; Kankare, M.

10.1101/2022.11.15.516589 — evolutionary biology — Posted on 2024-01-22

1673 ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

Hijaze, E.; Gildor, T.; Seidel, R.; Layous, M.; Winter, M.; Bertinetti, L.; Politi, Y.; de-Leon, S. B.-T.

10.1101/2022.12.21.521381 — developmental biology — Posted on 2024-01-22

1674 CHC22 clathrin functions in the early secretory pathway by two-site interaction with SNX5 and p115

Greig, J.; Bates, G. T.; Yin, D. I.; Simonetti, B.; Cullen, P. J.; Brodsky, F. M.

10.1101/2022.12.21.520923 — cell biology — Posted on 2024-01-22

1675 High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes

Locke, T. M.; Fields, R.; Gizinski, H.; Otto, G. M.; Shechner, D. M.; Berg, M. D.; Villen, J.; Sancak, Y.; Schweppe, D. K.

10.1101/2024.01.18.575273 — cell biology — Posted on 2024-01-22

1676 Impact of operational conditions on drinking water biofilm dynamics and coliform invasion potential

Waegenaar, F.; Garcia-Timermans, C.; Van Landuyt, J.; Gusseme, B. D.; Boon, N.

10.1101/2023.09.21.558492 — microbiology — Posted on 2024-01-22

1677 Identification of functional white matter networks in BOLD fMRI

Eby, A. L.; Remedios, L. W.; Kim, M. E.; Li, M.; Gao, Y.; Gore, J.; Schilling, K.; Landman, B. A.

10.1101/2023.09.08.556881 — neuroscience — Posted on 2024-01-22

1678 Histidine 73 methylation coordinates ????-actin plasticity in response to key environmental factors

Schahl, A.; Lagardere, L.; Walker, B.; Ren, P.; Wioland, H.; Ballet, M.; JEGOU, A.; Chavent, M.; Piquemal, J.-P.

10.1101/2022.12.16.520803 — biophysics — Posted on 2024-01-22

1679 Restraint Validation of Biomolecular Structures Determined by NMR in the Protein Data Bank

Baskaran, K.; Ploskon, E.; Tejero, R.; Yokochi, M.; Harrus, D.; Liang, Y.; Peisach, E.; Persikova, I.; Ramelot, T. A.; Sekharan, M.; Tolchard, J.; Westbrook, J. D.; Bardiaux, B.; Schwieters, C.; Patwardhan, A.; Velankar, S.; Burley, S. K.; Kurisu, G.; Hoch, J. C.; Montelione, G. T.; Vuister, G. W.; Young, J. Y.

10.1101/2024.01.15.575520 — bioinformatics — Posted on 2024-01-22

1680 Ratiometric pH Imaging of Macrophage Lysosomes Using the Novel pH-sensitive Dye ApHID.

Sole-Domenech, S.; Kumar Singh, P.; Warren, J. D.; Maxfield, F. R.

10.1101/2024.01.20.576118 — biochemistry — Posted on 2024-01-22

1681 Transgenerational virulence: Maternal pathogen exposure reduces offspring fitness

McIntire, K. M.; Dziuba, M. K.; Haywood, E. B.; Robertson, M. L.; Vaandrager, M.; Baird, E.; Corcoran, F.; Nelson, T.; Cortez, M. H.; Duffy, M. A.

10.1101/2023.03.14.532659 — ecology — Posted on 2024-01-22

1682 Retinal waves in adaptive rewiring networks orchestrate convergence and divergence in the visual system

Luna, R.; Li, J.; Bauer, R.; Leeuwen, C. v.

10.1101/2023.10.11.561834 — neuroscience — Posted on 2024-01-22

1683 Of mice and men: topologically complex dendrites assemble uniquely human networks

Kanari, L.; Shi, Y.; Arnaudon, A.; Barros Zulaica, N.; Benavides-Piccione, R.; Coggan, J. S.; DeFelipe, J. D.; Hess, K.; Mansvelder, H.; Mertens, E. J.; Meystre, J.; Perin, R. d. C.; Pezzoli, M.; Daniel, R. T.; Stoop, R.; Segev, I.; Markram, H.; de Kock, C. P.

10.1101/2023.09.11.557170 — neuroscience — Posted on 2024-01-22

1684 Antibody targeting of surface PSGL-1 glycoprotein leads to lymphoma apoptosis and tumorigenesis inhibition

Pereira, J. L.; Ferreira, F.; dos Santos, N. R.

10.1101/2024.01.18.576249 — cancer biology — Posted on 2024-01-22

1685 Adsorption-driven deformation and landing-footprints of the RBD proteins in SARS-CoV-2 variants onto biological and inanimate surfaces

Bosch, A.; V. Guzman, H.; Perez, R.

10.1101/2024.01.15.575706 — biophysics — Posted on 2024-01-22

1686 Biophysical principles predict fitness of SARS-CoV-2 variants

Wang, D.; Huot, M.; Mohanty, V.; Shakhnovich, E. I.

10.1101/2023.07.23.549087 — biophysics — Posted on 2024-01-22

1687 Quantifying Interpretation Reproducibility in Vision Transformer Models with TAVAC

Zhao, Y.; Agyemang, D.; Liu, Y.; Mahoney, M.; Li, S.

10.1101/2024.01.18.576252 — bioinformatics — Posted on 2024-01-22

1688 Current limitations in predicting mRNA translation with deep learning models

Schlusser, N.; Gonzalez, A.; Pandey, M.; Zavolan, M.

10.1101/2024.01.18.576214 — bioinformatics — Posted on 2024-01-22

1689 Evaluation of Deep Learning for predicting rice traits using structural and single-nucleotide genomic variants

Vourlaki, I.-T.; Ramos-Onsins, S. E.; Perez-Enciso, M.; Castanera, R.

10.1101/2024.01.18.576088 — genomics — Posted on 2024-01-22

1690 WITHDRAWN: (CA)n oligonucleotides correct RNA mis-splicing in TDP-43 pathology

Wang, C.; Terrigno, M.; Joenson, L.; Li, M.; Schroeter, M.; Nordbo, B.; Chyzynska, K.; Weile, C.; Bastien, J.; Mogensen, M. B.; Seidel, A. S.; Hagedorn, P. H.; Jagasia, R.; Vikesaa, J.

10.1101/2023.12.21.572777 — molecular biology — Posted on 2024-01-22

1691 Intracellular pH links energy metabolism to lymphocyte death and proliferation

Zeng, W.-p.; Yang, S.; Zhou, B.

10.1101/2021.10.29.466539 — immunology — Posted on 2024-01-22

1692 Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations

Lederer, A. R.; Leonardi, M.; Talamanca, L.; Herrera, A.; Droin, C.; Khven, I.; Carvalho, H. J.; Valente, A.; Dominguez Mantes, A.; Mulet Arabi, P.; Pinello, L.; Naef, F.; La Manno, G.

10.1101/2024.01.18.576093 — systems biology — Posted on 2024-01-22

1693 Ultra-efficient, unified discovery from microbial sequencing with SPLASH and precise statistical assembly

Henderson, G.; Gudys, A.; Baharav, T.; Sundaramurthy, P.; Kokot, M.; Wang, P. L.; Deorowicz, S.; Carey, A.; Salzman, J.

10.1101/2024.01.18.576133 — bioinformatics — Posted on 2024-01-22

1694 Cell Type-Agnostic Optical Perturbation Screening Using Nuclear In-Situ Sequencing (NIS-Seq)

Fandrey, C. I.; Konopka, P.; Jentzsch, M.; Zackria, A. A.; Maasewerd, S.; Latz, E.; Schmid-Burgk, J. L.

10.1101/2024.01.18.576210 — genomics — Posted on 2024-01-22

1695 Monitoring transcription of miR-15a and miR-124 in mesenchymal stem cells from adipose tissue origin differentiated into pancreatic beta-cells

Rajabi, H.

10.1101/2024.01.18.576237 — cell biology — Posted on 2024-01-22

1696 Speedy benthi: Elongated photoperiods reduce the generation time of the model plant species Nicotiana benthamiana

Castle, M.; Luedke, D.

10.1101/2024.01.18.576090 — plant biology — Posted on 2024-01-22

1697 Targeted DNA Sequencing of Cutaneous Melanoma Identifies Prognostic and Predictive Alterations

Vasudevan, H.; Haugh, A. M.; Osorio, R. C.; Francois, R. A.; Tawil, M. E.; Tsai, K. K.; Tetzlaff, M.; Daud, A.

10.1101/2024.01.18.576113 — cancer biology — Posted on 2024-01-22

1698 Dissecting the membrane association mechanism of aerolysin pore at femtomolar concentrations using water as a probe

Roesel, T.; Cao, C.; Bada Juarez, J. F.; Dal Peraro, M.; Roke, S.

10.1101/2024.01.18.576179 — biophysics — Posted on 2024-01-22

1699 Programmable DNA shell scaffolds for directional membrane budding

Dietz, H.; Pinner, M. T.

10.1101/2024.01.18.576181 — biophysics — Posted on 2024-01-22

1700 Pre-trained Maldi Transformers improve MALDI-TOF MS-based prediction

De Waele, G.; Menschaert, G.; Vandamme, P.; Waegeman, W.

10.1101/2024.01.18.576189 — bioinformatics — Posted on 2024-01-22

1701 ProtHyena: A fast and efficient foundation protein language model at single amino acid resolution

Zhang, Y.

10.1101/2024.01.18.576206 — bioinformatics — Posted on 2024-01-22

1702 Development of a metabolic engineering technology to simultaneously suppress the expression of multiple genes in yeast and application in carotenoid production

Yamada, R.; Yamamoto, C.; Sakaguchi, R.; Matsumoto, T.; Ogino, H.

10.1101/2024.01.18.576177 — bioengineering — Posted on 2024-01-22

1703 A low-cost protocol for reconditioning of deep-brain neural microelectrodes with material failure for electrophysiology recording

Rezayat, L.; Ghajar, M. H.; Naji, A.; Nourozi, J.; Dehaqani, M.-R. A.; Rezayat, E.

10.1101/2024.01.17.576102 — bioengineering — Posted on 2024-01-22

1704 Genome-Wide Association Insights into the Genomic Regions Controlling Oil Production Traits in Acrocomia aculeata (neotropical native palm)

Couto, E. G. d. O.; Morales-Marroquin, J.; Alves-Pereira, A.; Fernandes, S. B.; Colombo, C. A.; Azevedo-Filho, J.; Carvalho, C. R. L.; Zucchi, M. I.

10.1101/2024.01.17.576138 — genetics — Posted on 2024-01-22

1705 The integration of network biology and pharmacophore modeling suggests repurposing Clindamycin as an inhibitor of pyroptosis via Caspase-1 blockage in tumor-associated macrophages

Weich, A.; Flamann, C.; Berges, J.; Singh, K. P.; Chambers, D.; Lai, X.; Wolkenhauer, O.; Berking, C.; Kroenke, G.; Gupta, S.; Bruns, H.; Vera Gonzalez, J.

10.1101/2024.01.18.576201 — systems biology — Posted on 2024-01-22

1706 FROM DUST TO SEED: A LUNAR CHICKPEA STORY

Atkin, J.; Oliveira Pedro dos Santos, S.

10.1101/2024.01.18.576311 — plant biology — Posted on 2024-01-22

1707 M2WISH: an easy and efficient protocol for whole-mount mRNA in situ hybridization that allows 3D cell resolution of gene expression in Arabidopsis thaliana.

Chelysheva, L.; Palauqui, J.-C.; Morin, H.; Biot, E.; Nicolas, A.; Rech, P.; da Costa, M.; Barel, L.; Laufs, P.

10.1101/2024.01.18.576197 — plant biology — Posted on 2024-01-22

1708 The stability of lower genital tract microbiota correlates with reproductive system function and in vitro fertilization and frozen embryo transfer outcomes in women with polycystic ovarian syndrome

Tu, Y.; Huang, H.; Jin, L.; Zhang, Y.; Chen, H.; Wei, B.; Ge, Y.; Ding, G.; Dong, X.; Sheng, J.

10.1101/2024.01.18.576212 — physiology — Posted on 2024-01-22

1709 Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions

Tafech, B.; Rokhforouz, M.-R.; Leung, J.; Sung, M.; Lin, P.; Sin, D.; Lauster, D.; Block, S.; Quon, B.; Tam, Y.; Cullis, P.; Feng, J. J.; Hedtrich, S.

10.1101/2024.01.18.575680 — bioengineering — Posted on 2024-01-22

1710 Geographic variation in resistance of the invasive Drosophila suzukii to parasitism by the biological control agent, Ganaspis brasiliensis

Istas, O.; Szucs, M.

10.1101/2024.01.18.576198 — evolutionary biology — Posted on 2024-01-22

1711 Noncaloric monosaccharides induce excessive sprouting angiogenesis in zebrafish via foxo1a-marcksl1a signal

Wang, X.; Zhao, J.; Xu, J.; Li, B.; Liu, X.; Xie, G.; Duan, X.; Liu, D.

10.1101/2024.01.18.576182 — pharmacology and toxicology — Posted on 2024-01-22

1712 Identification of motor unit discharges from ultrasound images: Analysis of in silico and in vivo experiments

Rohlen, R.; Lubel, E.; Farina, D.

10.1101/2024.01.18.576300 — bioengineering — Posted on 2024-01-22

1713 Vertically inherited microbiota and environment modifying behaviors conceal genetic variation in dung beetle life history

Rohner, P. T.; Moczek, A.

10.1101/2024.01.17.576108 — evolutionary biology — Posted on 2024-01-22

1714 Takakia possesses a key marker of embryophyte sporopollenin

Suh, D.-Y.; Sraan, D. K.; Ashton, N. W.

10.1101/2024.01.17.576121 — evolutionary biology — Posted on 2024-01-22

1715 fastDFE: fast and flexible inference of the distribution of fitness effects

Sendrowski, J.; Bataillon, T.

10.1101/2023.12.04.569837 — evolutionary biology — Posted on 2024-01-22

1716 Parasite contingency loci and the evolution of host specificity: Simple sequence repeats mediate Bartonella adaptation to a wild rodent host

Rodriguez-Pastor, R.; Knossow, N.; Shahar, N.; Hasik, A. Z.; Deatherage, D. E.; Gutierrez, R.; Harrus, S.; Zaman, L. E.; Lenski, R. E.; Barrick, J. E.; Hawlena, H.

10.1101/2024.01.18.576196 — evolutionary biology — Posted on 2024-01-22

1717 A video-rate hyperspectral camera for monitoring plant health and biodiversity

Brooks, L. J.; Pearce, D.; Kwok, K.; Jawade, N.; Qi, M.; Fenollosa, E.; Beker, D.; Whicker, J.; Davis, K.; Salguero-Gomez, R.; Wang, R.; Chappell, S.

10.1101/2024.01.18.576183 — ecology — Posted on 2024-01-22

1718 Testing for reciprocal trait influence in plant-frugivore interactions using generalized joint attribute modeling

Yohe, L. R.; Leiser-Miller, L. B.; Kaliszewska, Z. A.; Whitehead, S. R.; Santana, S. E.; Davalos, L. M.

10.1101/2024.01.17.576112 — ecology — Posted on 2024-01-22

1719 Metabolic responses to cold: thermal physiology of native common waxbills (Estrilda astrild)

Pacioni, C.; Sentis, M.; Kerimov, A.; Bushiev, A.; Downs, C.; Lens, L.; Strubbe, D.

10.1101/2024.01.18.576192 — ecology — Posted on 2024-01-22

1720 Patient Subtyping Analysis of Baseline Multi-omic Data Reveals Distinct Pre-immune States Predictive of Vaccination Responses

Sevim Bayrak, C.; Forst, C.; Jones, D. R.; Gresham, D. J.; Pushalkar, S.; Wu, S.; Vogel, C.; Mahal, L. K.; Ghedin, E.; Ross, T.; Garcia-Sastre, A.; Zhang, B.

10.1101/2024.01.18.576213 — immunology — Posted on 2024-01-22

1721 Cross-institutional HER2 assessment via a computer-aided system using federated learning and stain composition augmentation

Yang, C.-H.; Chen, Y.-A.; Chang, S.-Y.; Hsieh, Y.-H.; Hung, Y.-L.; Lin, Y.-W.; Lee, Y.-H.; Lin, C.-H.; Lin, Y.-C.; Lu, Y.-S.; Lin, Y.-Y.

10.1101/2024.01.17.576160 — pathology — Posted on 2024-01-22

1722 Springs vs. motors: Ideal assistance in the lower limbs during walking at different speeds

Luis, I.; Afschrift, M.; Gutierrez-Farewik, E. M.

10.1101/2024.01.18.576164 — bioengineering — Posted on 2024-01-22

1723 Magnetic Microtweezers for High-Throughput Bioseparation in Sub-Nanoliter Droplets

Dumas, S.; Alexandre, L.; Richerd, M.; Serra, M.; Descroix, S.

10.1101/2024.01.18.576187 — bioengineering — Posted on 2024-01-22

1724 Czech Republic butterfly barcoding reveals that distribution of genetic lineages depends on species traits

Suchackova Bartonova, A.; Skopek, P.; Konvicka, M.; Benes, J.; Spitzer, L.; Sbaraglia, C.; Vrabec, V.; Papp Maresova, J.; Konvickova, H.; Faltynek Fric, Z.

10.1101/2024.01.17.576072 — ecology — Posted on 2024-01-22

1725 Coordination of cell cycle and morphogenesis during organ formation

Matthew, J.; Vishwakarma, V.; Le, T. P.; Agsunod, R. A.; Chung, S.

10.1101/2023.07.20.549944 — developmental biology — Posted on 2024-01-22

1726 RAN translation of C9ORF72-related dipeptide repeat proteins recapitulates hallmarks of motor neurone disease and identifies hypothermia as a therapeutic strategy in zebrafish

Burrows, D. J.; McGown, A.; Abduljabbar, O.; Castelli, L. M.; Shaw, P. J.; Hautbergue, G. M.; Ramesh, T. M.

10.1101/2024.01.17.576077 — molecular biology — Posted on 2024-01-22

1727 Mechanistic explanation of neuroplasticity using equivalent circuits

Nilsson, M. N. P.

10.1101/2023.05.21.541639 — neuroscience — Posted on 2024-01-22

1728 Collective movement of schooling fish reduces locomotor cost in turbulence

zhang, y.; Ko, H.; Calicchia, M. A.; Ni, R.; Lauder, G.

10.1101/2024.01.18.576168 — physiology — Posted on 2024-01-22

1729 Biophysical characterization and analysis of a mesophilic chorismate mutase from B. pumilus

Wilkins, R. S.; Lund, B. A.; Isaksen, G. V.; Aqvist, J.; Brandsdal, B. O.

10.1101/2023.04.20.537678 — biochemistry — Posted on 2024-01-22

1730 Genomic diversity and antimicrobial resistance in clinical Klebsiella pneumoniae isolates from tertiary hospitals in Southern Ghana

Mills, R. O.; Dadzie, I.; Le-Viet, T.; Baker, D. J.; Addy, H. P. K.; Akwetey, S. A.; Donkoh, I. E.; Quansah, E.; Semanshia, P. S.; Morgan, J.; Mensah, A.; Adade, N. E.; Ampah, E. O.; Owusu, E.; Mwintige, P.; Amoako, E. O.; Spadar, A.; Holt, K. E.; Foster-Nyarko, E.

10.1101/2024.01.20.576413 — genomics — Posted on 2024-01-22

1731 Borrelia burgdorferi PlzA is a cyclic-di-GMP dependent DNA- and RNA-binding protein

Jusufovic, N.; Krusenstjerna, A. C.; Savage, C.; Saylor, T. C.; Brissette, C. A.; Zueckert, W. R.; Schlax, P.; MOTALEB, M. A. R.; Stevenson, B.

10.1101/2023.01.30.526351 — microbiology — Posted on 2024-01-22

1732 Deferoxamine as adjunct therapeutics for tuberculosis

Kaushik, S. R.; Yadav, N.; Sahu, S.; Gupta, A.; Mohapatra, A. K.; Sarangi, A.; Kumari, S.; Biswal, B.; Nanda, R.

10.1101/2023.06.02.543389 — microbiology — Posted on 2024-01-22

1733 The Beta secretase BACE1 drives fibroblasts activation in Systemic Sclerosis through the APP/Beta-catenin/Notch signalling axis

Wasson, C. W.; De Lorenzis, E.; Clavane, E. M.; Ross, R. L.; Walker, K. A.; Caballero-Ruiz, B.; Antinozzi, C.; Wells, R.; Migneco, G.; Brown, J. M. Y.; Riobo-Del Galdo, N. A.; Di Luigi, L.; McKimmie, C. S.; Del Galdo, F.; Meakin, P. J.

10.1101/2022.12.22.521579 — immunology — Posted on 2024-01-22

1734 Shared Transcriptomic Signatures of Inflammaging Among Diverse Strains of Drosophila melanogaster

Perna, S. I.; Tang, W.; Blimbaum, S. D.; Li, A. Y.; Zhou, L.

10.1101/2024.01.17.576061 — immunology — Posted on 2024-01-22

1735 Herpes zoster mRNA vaccine induces superior vaccine immunity over licensed vaccine in mice and rhesus macaques

Huang, L.; Zhao, T.; Zhao, W.; Shao, A.; Shao, A.; Zhao, H.; Ma, W.; Gong, Y.; Zeng, X.; Weng, C.; Bu, L.; Di, Z.; Sun, S.; Dai, Q.; Sun, M.; Wang, L.; Liu, Z.; Shi, L.; Hu, J.; Fang, S.; Zhang, C.; Zhang, J.; Wang, G.; Lore, K.; Yang, Y.; Lin, A.

10.1101/2023.08.16.553640 — immunology — Posted on 2024-01-22

1736 Altered physiological, affective, and functional connectivity responses to acute stress in patients with alcohol use disorder

Schwarze, Y.; Voges, J.; Schröder, A.; Dreessen, S.; Voss, O.; Krach, S.; Paulus, F. M.; Junghanns, K.; Rademacher, L.

10.1101/2024.01.18.576207 — neuroscience — Posted on 2024-01-22

1737 Transcranial direct current stimulation alters cerebrospinal fluid-interstitial fluid exchange in mouse brain

Wang, Y.; Monai, H.

10.1101/2023.12.30.573695 — neuroscience — Posted on 2024-01-22

1738 A mean-field theory for predicting single polymer collapse induced by neutral crowders

Chaboche, Q.; Campos-Villalobos, G.; Giunta, G.; Dijkstra, M.; Cosentino Lagomarsino, M.; Scolari, V. F.

10.1101/2023.07.12.548683 — biophysics — Posted on 2024-01-22

1739 Transgenic αβ TCR tonic signaling is leukemogenic while strong stimulation is leukemia-suppressive

Catarino, T. A.; Pacheco-Leyva, I.; Pereira, J. L.; Baessa, M.; dos Santos, N. R.

10.1101/2024.01.17.576006 — cancer biology — Posted on 2024-01-22

1740 Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

Curylova, L.; Staniczkova Zambo, I.; Neradil, J.; Kyr, M.; Jurackova, N.; Pavlova, S.; Polaskova, K.; Mudry, P.; Sterba, J.; Veselska, R.; Skoda, J.

10.1101/2024.01.17.576012 — cancer biology — Posted on 2024-01-22

1741 Single-nucleotide-resolution genomic maps of O6-methylguanine from the glioblastoma drug temozolomide

Buechel, J.; Mingard, C.; Takhaveev, V.; Reinert, P. B.; Keller, G.; Kloter, T.; Huber, S.; McKeague, M.; Sturla, S. J.

10.1101/2023.12.12.571283 — cancer biology — Posted on 2024-01-22

1742 Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas

Nair, N. U.; Schaffer, A. A.; Gertz, M. E.; Cheng, K.; Zerbib, J.; Sahu, A. D.; Leor, G.; Shulman, E. D.; Aldape, K. D.; Ben-David, U.; Ruppin, E.

10.1101/2024.01.17.576103 — cancer biology — Posted on 2024-01-22

1743 Integrative genomic analysis identifies unique immune environments associated with immunotherapy response in diffuse large B cell lymphoma

Tumuluru, S.; Godfrey, J. K.; Cooper, A.; Yu, J.; Chen, X.; MacNabb, B. W.; Venkataraman, G.; Zha, Y.; Pelzer, B.; Song, J.; Duns, G.; Bolen, C.; Penuel, E.; Postovalova, E.; Kotlov, N.; Bagaev, A.; Fowler, N.; Smith, S. M.; Steidl, C.; Kline, J.

10.1101/2024.01.17.576100 — cancer biology — Posted on 2024-01-22

1744 Integrated cancer cell-specific single-cell RNA-seq datasets of immune checkpoint blockade-treated patients

Gondal, M. N.; Cieslik, M.; Chinnaiyan, A. M.

10.1101/2024.01.17.576110 — cancer biology — Posted on 2024-01-22

1745 LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer

Mandl, A.; Jasmine, S.; Krueger, T. E. G.; Kumar, R.; Coleman, I. M.; Dalrymple, S. L.; Antony, L.; Rosen, D. M.; Jing, Y.; Hanratty, B.; Patel, R. A.; Low, J.-Y.; Dias, J.; Celatka, C. A.; Tapper, A. E.; Kleppe, M.; Kanayama, M.; Speranzini, V.; Wang, Y.; Luo, J.; Corey, E.; Sena, L. A.; Casero, R. A.; Lotan, T.; Trock, B. J.; Kachhap, S. K.; Denmeade, S. R.; Carducci, M. A.; Mattevi, A.; Haffner, M. C.; Nelson, P. S.; Rienhoff, H. H.; Isaacs, J. T.; Brennen, W. N.

10.1101/2024.01.17.576106 — cancer biology — Posted on 2024-01-22

1746 Aggregation of recount3 RNA-seq data improves the inference of consensus and tissue-specific gene co-expression networks.

Battle, A.; Ravichandran, P.; Parsana, P.; Keener, R.; Hansen, K.

10.1101/2024.01.20.576447 — genomics — Posted on 2024-01-22

1747 Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D Geometric Morphometrics reveals wide-gauge posture as an exaptation for gigantism

Paramo Blazquez, A.; Mocho, P.; Escaso, F.; Ortega, F.

10.1101/2023.10.04.560839 — paleontology — Posted on 2024-01-22

1748 Dynamics, Electrostatics, and Thermodynamics ofBase Pairing at the LTR-III Quadruplex:Duplex Junction

Michel, H. M.; Lemkul, J. A.

10.1101/2024.01.17.576154 — biophysics — Posted on 2024-01-22

1749 Proteostatic tuning underpins the evolution of novel multicellular traits

Montrose, K.; Lac, D. T.; Burnetti, A. J.; Tong, K.; Bozdag, G. O.; Hukkanen, M.; Ratcliff, W. C.; Saarikangas, J.

10.1101/2023.05.31.543183 — evolutionary biology — Posted on 2024-01-22

1750 Gene protein sequence evolution can predict the rapid divergence of ovariole numbers in Drosophila

Whittle, C.; Extavour, C. G.

10.1101/2023.09.03.556080 — evolutionary biology — Posted on 2024-01-22

1751 Short-term passive greenspace exposures have little effect on nasal microbiomes: a cross-over exposure study of a Maori cohort

Brame, J.; Warbrick, I.; Heke, D.; Liddicoat, C.; Breed, M.

10.1101/2024.01.17.576148 — ecology — Posted on 2024-01-22

1752 Bacterial quorum sensing controls carbon metabolism to optimize growth in changing environmental conditions.

Simpson, C. A.; Celentano, Z.; McKinlay, J. B.; Nadell, C.; van Kessel, J. C.

10.1101/2024.01.21.576522 — microbiology — Posted on 2024-01-22

1753 Transfer of modified fecal viromes improve blood glucose regulation and alleviates symptoms of metabolic dysfunction-associated fatty liver disease in an obesity male mouse model

Mao, X.; Larsen, S. B.; Zachariassen, L. S. F.; Brunse, A.; Adamberg, S.; Castro-Mejia, J. L.; Larsen, F.; Adamberg, K.; Nielsen, D. S.; Hansen, A. K.; Hansen, C. H. F.; Rasmussen, T. S.

10.1101/2023.03.20.532903 — microbiology — Posted on 2024-01-22

1754 Amino acid usage and tRNA expression underlies proteome adaptation in Plasmodium falciparum

Li, Q.; Vetter, L.; Veith, Y.; Christ, E.; Vegvari, A.; Sahin, C.; Ribacke, U.; Wahlgren, M.; Ankarklev, J.; Larsson, O.; Chan, S. C. L.

10.1101/2023.03.20.533258 — microbiology — Posted on 2024-01-22

1755 cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens.

WANG, Y. Z.; Natsume, K.; Tanaka, T.; Hososhima, S.; Tashiro, R.; Sano, F.; Akasaka, H.; Tsunoda, S.; Shihoya, W.; Kandori, H.; Nureki, O.

10.1101/2024.01.21.576531 — biochemistry — Posted on 2024-01-22

1756 Elucidating the Role of Primary and Secondary Sphere Zn2+ Ligands in the Cyanobacterial CO2 Uptake Complex NDH-14: The Essentiality of Arginine in Zinc Coordination and Catalysis

Walker, R. M.; Zhang, M.; Burnap, R. L.

10.1101/2024.01.20.576359 — biochemistry — Posted on 2024-01-22

1757 Structure of hepatitis B/D antiviral drug Bulevirtide bound to its receptor protein NTCP

Liu, H.; Zakrzewicz, D.; Nosol, K.; Irobalieva, R. N.; Mukherjee, S.; Bang-Soerensen, R.; Goldmann, N.; Kunz, S.; Rossi, L.; Kossiakoff, A. A.; Urban, S.; Glebe, D.; Geyer, J.; Locher, K. P.

10.1101/2024.01.22.576510 — biochemistry — Posted on 2024-01-22

1758 Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications

Ctortecka, C.; Clark, N. M.; Boyle, B.; Seth, A.; Mani, D. R.; Udeshi, N.; Carr, S. A.

10.1101/2024.01.20.576369 — biochemistry — Posted on 2024-01-22

1759 A complex Plasmodium falciparum cryptotype circulating at low frequency across the African continent

Miotto, O.; Amambua-Ngwa, A.; Amenga-Etego, L. N.; Abdel Hamid, M. M.; Adam, I.; Aninagyei, E.; Apinjoh, T.; Awandare, G. A.; Bejon, P.; Bertin, G.; Bouyou-Akotet, M. K.; Claessens, A.; Conway, D.; D'Alessandro, U.; Diakite, M.; Djimde, A.; Dondorp, A. M.; Duffy, P.; Fairhurst, R. M.; Fanello, C. I.; Ghansah, A.; Ishengoma, D.; Lawniczak, M.; Maiga-Ascofare, O.; Auburn, S.; Rosanas-Urgell, A.; Wasakul, V.; White, N.; Almagro-Garcia, J.; Pearson, R.; Goncalves, S.; Ariani, C.; Bozdech, Z.; Hamilton, W. L.; Simpson, V.; Kwiatkowski, D. P.

10.1101/2024.01.20.576496 — genomics — Posted on 2024-01-22

1760 Convergent evolution of noxious heat sensing by TRPA5, a novel class of heat sensor in Rhodnius prolixus

Lienard, M. A.; Baez-Nieto, D.; Tsai, C.-C.; Valencia-Montoya, W. A.; Werin, B.; Johanson, U.; Lassance, J.-M.; Pan, J. Q.; Yu, N.; Pierce, N. E.

10.1101/2023.05.26.542450 — evolutionary biology — Posted on 2024-01-22

1761 Bayesian Estimation of Cooccurrence Affinity with Dyadic Regression

Newbury, A.

10.1101/2024.01.16.575941 — ecology — Posted on 2024-01-22

1762 Decomposing drivers in avian insectivory: large-scale effects of climate, habitat and bird diversity

SCHILLE, L.; VALDES-CORRECHER, E.; ARCHAUX, F.; BALACENOIU, F.; BJOERN, M. C.; BOGDZIEWICZ, M.; BOIVIN, T.; BRANCO, M.; DAMESTOY, T.; DE GROOT, M.; DOBROSAVLJEVIC, J.; DUDUMAN, M.-L.; DULAURENT, A.-M.; GREEN, S.; GRUNWALD, J.; EOTVOS, C. B.; FATICOV, M.; FERNANDEZ-CONRADI, P.; FLURY, E.; FUNOSAS, D.; GALMAN, A.; GOSSNER, M. M.; GRIPENBERG, S.; GROSU, L.; Hagge, J.; HAMPE, A.; HARVEY, D.; HOUSTON, R.; ISENMANN, R.; KAVCIC, A.; KOZLOV, M. V.; LANTA, V.; LE TILLY, B.; LOPEZ VAAMONDE, C.; MALLICK, S.; MANTYLA, E.; MARELL, A.; MILANOVIC, S.; MOLNAR, M.; MOREIRA, X.; MOSER, V.; MRAZOVA, A.; MUSOLIN,

10.1101/2023.01.19.524212 — ecology — Posted on 2024-01-22

1763 3D environment promotes persistent changes in lamin B1 distribution, the biomechanical signature of the nucleus, and adaptative survival and migratory functions.

Gonzalez-Novo, R.; Zamora Carreras, H.; De Lope-Planelles, A.; Lopez-Menendez, H.; Roda-Navarro, p.; Monroy, F.; Wang, L.; Toseland, C. P.; Redondo-Munoz, J.

10.1101/2023.04.10.536202 — cell biology — Posted on 2024-01-22

1764 Strand asymmetry of DNA damage tolerance mechanisms

Canas, J. C.; Santiago, D.; Mamun, M.; Sacristan, M.; Morafraile, E.; Zamarreno, J.; Fujiki, K.; Shirahige, K.; Bueno, A.; Bermejo, R.

10.1101/2024.01.21.576515 — molecular biology — Posted on 2024-01-22

1765 Cryo-EM analysis on magnetic beads for scarce macromolecules in heterogeneous samples

Arimura, Y.; Konishi, H. A.; Funabiki, H.

10.1101/2024.01.21.576499 — molecular biology — Posted on 2024-01-22

1766 ciRS-7 and miR7 regulate ischemia induced neuronal death via glutamatergic signaling

Scoyni, F.; Sitnikova, V.; Giudice, L.; Korhonen, P.; Trevisan, D. M.; Hernandez de Sande, A.; Gomez-Budia, M.; Giniatullina, R.; Ugidos, I. F.; Dhungana, H.; Pistono, C.; Korvenlaita, N.; Valimaki, N.-N.; Kangas, S. M.; Hiltunen, A. E.; Gribchenko, E.; Kaikkonen-Maatta, M. U.; Koistinaho, J.; Yla-Herttuala, S.; Hinttala, R.; Veno, M. T.; Su, J.; Stoffel, M.; Schaefer, A.; Rajewsky, N.; Kjems, J.; La Pierre, M. P.; Piwecka, M.; Jolkkonen, J.; Giniatullin, R.; Hansen, T. B.; Malm, T.

10.1101/2023.01.24.525136 — molecular biology — Posted on 2024-01-22

1767 The transcriptional and translational landscape of HCoV-OC43 infection

Bresson, S.; Sani, E.; Armatowska, A.; Dixon, C.; Tollervey, D.

10.1101/2024.01.20.576440 — microbiology — Posted on 2024-01-22

1768 Conjugation related costs have reduced impact on in silico plasmid persistence

Newbury, A.

10.1101/2024.01.18.576315 — microbiology — Posted on 2024-01-22

1769 Exploring the Impact of Probiotic Route of Administration on Its Protective Effects against Pathogenic Infection in Galleria mellonella

Menta, L. N. K.; Tan, H. S.

10.1101/2024.01.20.576486 — microbiology — Posted on 2024-01-22

1770 Discovery of the 1-naphthylamine biodegradation pathway reveals an enzyme that catalyzes 1-naphthylamine glutamylation

Zhang, S.-T.; Deng, S.-K.; Li, T.; Maloney, M. E.; Li, D.-F.; C Spain, J.; Zhou, N.-Y.

10.1101/2024.01.21.576549 — microbiology — Posted on 2024-01-22

1771 A nutritional immunity blockade controls extracellular bacterial replication in Legionella pneumophila infections.

Torres-Escobar, A.; Wilkins, A.; Juarez-Rodriguez, M. D.; Circu, M.; Latimer, B.; Dragoi, A.-M.; Ivanov, S. S.

10.1101/2024.01.21.576562 — microbiology — Posted on 2024-01-22

1772 Orthogonalized human protease control of secreted signals

Aldrete, C. A.; Vlahos, A. E.; Pei, J.; Cong, Q.; Gao, X. J.

10.1101/2024.01.18.576308 — synthetic biology — Posted on 2024-01-22

1773 Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing

Reichmann, J.; Sarrazin, C.; Schmale, S.; Blaurock, C.; Balkema-Buschmann, A.; Schmitzer, B.; Salditt, T.

10.1101/2024.01.21.576083 — pathology — Posted on 2024-01-22

1774 CellTracksColab--A platform for compiling, analyzing, and exploring tracking data

Jacquemet, G.

10.1101/2023.10.20.563252 — bioinformatics — Posted on 2024-01-22

1775 Surface Patterned Omniphobic Tiles (SPOTs): a versatile platform for scalable liquid handling

Shiri, S.; Qazi, M. J.; Tan, S.; Albo, J.; Chen, A.; Fukuda, R.; Jain, M. S.; Menesses, M.; Nchinda, N.; Ahmed, G.; Gallegos, A.; Gangishetty, M.; Congreve, D.; Cira, N. J.

10.1101/2024.01.17.575712 — bioengineering — Posted on 2024-01-22

1776 Constraints on the Emergence of RNA through Non-Templated Primer Extension with Mixtures of Potentially Prebiotic Nucleotides

Jia, X.; Zhang, S. J.; Zhou, L.; Szostak, J. W.

10.1101/2024.01.21.576316 — biochemistry — Posted on 2024-01-22

1777 Identification of CK2α' selective inhibitors by the screening of an allosteric-kinase-inhibitor-like compound library

Mudaliar, D.; Mansky, R. H.; White, A.; Baudhuin, G.; Hawkinson, J.; Wong, H. L.; Walters, M. A.; Gomez-Pastor, R.

10.1101/2024.01.18.576328 — biochemistry — Posted on 2024-01-22

1778 Ratiometric pH Imaging of Macrophage Lysosomes Using the Novel pH-sensitive Dye ApHID.

Sole-Domenech, S.; Kumar Singh, P.; Warren, J. D.; Maxfield, F. R.

10.1101/2024.01.20.576118 — biochemistry — Posted on 2024-01-22

1779 PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation

Chin Sang, C.; Moore, G.; Tereshchenko, M.; Nosella, M. L.; Zhang, H.; Alderson, T. R.; Dasovich, M.; Leung, A.; Finkelstein, I. J.; Forman-Kay, J. D.; Lee, H. O.

10.1101/2024.01.20.575817 — biochemistry — Posted on 2024-01-22

1780 Beyond a unitary construct: Dissecting stopping behaviour in two bird species

Troisi, C. A.; Vernouillet, A.; Allaert, R.; Knoch, S.; Martel, A.; Lens, L.; Verbruggen, F.

10.1101/2024.01.17.575695 — animal behavior and cognition — Posted on 2024-01-22

1781 Cell type and regulatory analysis in amphioxus illuminates evolutionary origin of the vertebrate head

Markos, A.; Kubovciak, J.; Mikula Mrstakova, S.; Paces, J.; Zitova, A.; Kozmik, Z.; Machacova, S.; Kozmik, Z.; Kozmikova, I.

10.1101/2024.01.18.576194 — evolutionary biology — Posted on 2024-01-22

1782 A unified neural representation model for spatial and semantic computations

Haga, T.; Oseki, Y.; Fukai, T.

10.1101/2023.05.11.540307 — neuroscience — Posted on 2024-01-21

1783 Topographic, cognitive, and neurobiological profiling of the interdependent structural and functional connectome in the human brain

Wang, X.; Sun, L.; Liang, X.; Zhao, T.; Xia, M.; Liao, X.; He, Y.

10.1101/2024.01.21.576523 — neuroscience — Posted on 2024-01-22

1784 Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids

Dony, L.; Krontira, A. C.; Kaspar, L.; Ahmad, R.; Demirel, I. S.; Grochowicz, M.; Schaefer, T.; Begum, F.; Sportelli, V.; Raimundo, C.; Koedel, M.; Labeur, M.; Cappello, S.; Theis, F. J.; Cruceanu, C.; Binder, E. B.

10.1101/2024.01.21.576532 — neuroscience — Posted on 2024-01-22

1785 Mecp2 Fine-tunes Quiescence Exit by Targeting Nuclear Receptors

Yang, J.; Zou, S.; Qiu, Z.; Lai, M.; Long, Q.; Chen, H.; Lai, P.; Zhang, S.; Rao, Z.; Xie, X.; Gong, Y.; Liu, A.; Li, M.; Bai, X.

10.1101/2023.07.24.550263 — cell biology — Posted on 2024-01-21

1786 Priors for natural image statistics inform confidence in perceptual decisions

West, R. K.; A-Izzeddin, E. J.; Sewell, D. K.; Harrison, W. J.

10.1101/2023.02.19.529102 — neuroscience — Posted on 2024-01-21

1787 Infrared gas analysis as a method of measuring seagrass photosynthetic rate in the face of desiccation stress

Capistrant-Fossa, K. A.; Dunton, K. H.

10.1101/2024.01.16.575902 — plant biology — Posted on 2024-01-21

1788 Inhibition of Multiple Staphylococcal Growth States by a Small Molecule that Disrupts Membrane Fluidity and Voltage

Dombach, J. L.; Christensen, G. L.; Allgood, S. C.; Quintana, J. L.; Detweiler, C. S.

10.1101/2024.01.17.576101 — microbiology — Posted on 2024-01-21

1789 Increasing the accuracy of single-molecule data analysis using tMAVEN

Verma, A. R.; Ray, K. K.; Bodick, M. E.; Kinz-Thompson, C. D.; Gonzalez, R. L.

10.1101/2023.08.15.553409 — biophysics — Posted on 2024-01-21

1790 CellBoost: A pipeline for machine assisted annotation in neuroanatomy

Qian, K.; Friedman, B.; Takatoh, J.; Wang, F.; Kleinfeld, D.; Freund, Y.

10.1101/2023.09.13.557658 — neuroscience — Posted on 2024-01-21

1791 Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

Goldberg, A. R.; Dovas, A.; Torres, D.; Das Sharma, S.; Mela, A.; Merricks, E. M.; Olabarria, M.; Shokooh, L. A.; Zhao, H. T.; Kotidis, C.; Calvaresi, P.; Viswanathan, A.; Banu, M. A.; Razavilar, A.; Sudhakar, T. D.; Saxena, A.; Chokran, C.; Humala, N.; Mahajan, A.; Xu, W.; Metz, J. B.; Chen, C.; Bushong, E. A.; Boassa, D.; Ellisman, M. H.; Hillman, E. M. C.; McKhann, G. M.; Gill, B. J. A.; Rosenfeld, S. S.; Schevon, C. A.; Bruce, J. N.; Sims, P. A.; Peterka, D. S.; Canoll, P.

10.1101/2024.01.10.575092 — neuroscience — Posted on 2024-01-21

1792 Adipocyte PI3K links adipostasis with basal insulin secretion through an adipoincretin effect

Becattini, B.; Molinaro, A.; Henricsson, M.; Boren, J.; Solinas, G.

10.1101/2023.04.24.538076 — physiology — Posted on 2024-01-21

1793 Learning to quantify uncertainty in off-target activity for CRISPR guide RNAs

Ozden, F.; Minary, P.

10.1101/2023.06.02.543468 — bioinformatics — Posted on 2024-01-21

1794 Effects of Data Transformation and Model Selection on Feature Importance in Microbiome Classification Data

Org, E.; Kosciolek, T.; Biobank research team, E.; Aasmets, O.; Karwowska, Z.

10.1101/2023.09.19.558406 — bioinformatics — Posted on 2024-01-21

1795 Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase

Blomgren, L. K. M.; Huber, M.; Mackinnon, S. R.; Burer, C.; Basle, A.; Yue, W. W.; Froese, D. S.; McCorvie, T. J.

10.1101/2023.08.02.551630 — biochemistry — Posted on 2024-01-21

1796 Characterization of caffeine response regulatory variants in vascular endothelial cells

Boye, C.; Kalita, C.; Findley, A. S.; Alazizi, A.; Wei, J.; Wen, X.; Pique-Regi, R.; Luca, F.

10.1101/2022.11.22.517533 — genomics — Posted on 2024-01-21

1797 Human promoter CpG islands contain primate-specific repeats, cluster and resist reprogramming

Mohan, K. N.; Anne, A.; Kumar, L.; Chaillet, J. R.

10.1101/2024.01.17.576070 — developmental biology — Posted on 2024-01-21

1798 CLSTN3B enhances adipocyte lipid droplet structure and function via endoplasmic reticulum contact

Zhang, C.; Ye, M.; Melikov, K.; Yang, D.; Dias do Vale, G.; Mcdonald, J.; Eckert, K.; Lin, M.-J.; Zeng, X.

10.1101/2024.01.20.576491 — cell biology — Posted on 2024-01-21

1799 Phase partitioning rules Rab domain formation, growth and identity

Jimenez, A. J.; Divoux, S.; Goud, B.; Perez, F.

10.1101/2023.04.17.537227 — cell biology — Posted on 2024-01-21

1800 Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis

Joshi, D.; Coon, B. G.; Chakraborty, R.; Deng, H.; Fernandez Tussy, P.; Meredith, E.; Traylor, J. G.; Orr, A. W.; Fernandez-Hernando, C.; Schwartz, M. A.

10.1101/2024.01.16.575958 — cell biology — Posted on 2024-01-21

1801 Beyond the Colony-Forming-Unit: Rapid Bacterial Evaluation in Osteomyelitis

Sun, Q.; Huynh, K.; Muratovic, D.; Gunn, N. J.; Zelmer, A. R.; Solomon, L. B.; Atkins, G. J.; Yang, D.

10.1101/2023.11.21.568051 — microbiology — Posted on 2024-01-21

1802 Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

Weinberger, T.; Messerer, D.; Joppich, M.; Fischer, M.; Garcia, C.; Kumaraswami, K.; Wimmler, V.; Ablinger, S.; Raeuber, S.; Fang, J.; Liu, L.; Liu, W. H.; Winterhalter, J.; Lichti, J.; Tomas, L.; Esfandyari, D.; Percin, G.; Salamanca, S. M.; Hidalgo, A.; Waskow, C.; Engelhardt, S.; Todica, A.; Zimmer, R.; Pridans, C.; Gomez-Perdiguero, E.; Schulz, C.

10.1101/2023.05.08.539799 — immunology — Posted on 2024-01-21

1803 Neural manifolds carry reactivation of phonetic representations during semantic processing

Orepic, P.; Truccolo, W.; Halgren, E.; Cash, S. S.; Giraud, A.-L.; Proix, T.

10.1101/2023.10.30.564638 — neuroscience — Posted on 2024-01-21

1804 Important Role of Hematopoietic Proteoglycan Serglycin in Liver Hepatocellular Carcinoma Associated with Tumor Microenvironment

Zou, Z.; Xie, H.; Guo, W.; Li, Y.; Zhan, J.; Li, Y.

10.1101/2022.06.15.495916 — cancer biology — Posted on 2024-01-21

1805 Functional trade-offs: exploring the temporal response of field margin plant communities to climate change and agricultural practices

Poinas, I.; Meynard, C. N.; Fried, G.

10.1101/2023.03.03.530956 — ecology — Posted on 2024-01-21

1806 The calcium pump PMCA4b promotes epithelial cell polarization and lumen formation

Toth, S.; Kaszas, D.; Sonyak, J.; Tokes, A.-M.; Padanyi, R.; Papp, B.; Nagy, R.; Vörös, K.; Csizmadia, T.; Tordai, A.; Enyedi, A.

10.1101/2024.01.20.576436 — cell biology — Posted on 2024-01-21

1807 Osteoblast-Induced Collagen Alignment in a 3D in vitro Bone Model

Schaart, J. M.; Kea-te Lindert, M.; Roverts, R.; Nijhuis, W. H.; Sommerdijk, N.; Akiva, A.

10.1101/2023.11.17.567552 — cell biology — Posted on 2024-01-21

1808 Root associated Streptomyces produce galbonolides to modulate plant immunity and promote rhizosphere colonisation

Nicolle, C.; Gayrard, D.; Noel, A.; Hortala, M.; Amiel, A.; Grat-Simeone, S.; Le Ru, A.; Marti, G.; Pernodet, J.-L.; Lautru, S.; Dumas, B.; Rey, T.

10.1101/2024.01.20.576418 — microbiology — Posted on 2024-01-21

1809 Calcitriol impairs the secretion of IL-4 and IL-13 in Th2 cells via modulating VDR-Gata3-Gfi1 axis

Biswas, B.; Chattopadhyay, S.; Hazra, S.; Goswami, R.

10.1101/2023.12.03.569823 — immunology — Posted on 2024-01-21

1810 Interactions between saccades and smooth pursuit eye movements in marmosets

Pattadkal, J. J.; Barr, C.; Priebe, N. J.

10.1101/2024.01.07.574533 — neuroscience — Posted on 2024-01-21

1811 The Calcitron: A Simple Neuron Model That Implements Many Learning Rules via the Calcium Control Hypothesis

Moldwin, T.; Azran, L. S.; Segev, I.

10.1101/2024.01.16.575890 — neuroscience — Posted on 2024-01-21

1812 Context dependent contributions of the direct and indirect pathways in the associative and sensorimotor striatum

Cuevas, N.; Llanos-Moreno, A.; Ramirez-Armenta, K. I.; Alatriste-Leon, H.; Ramirez-Jarquin, J. O.; Tecuapetla, F.

10.1101/2024.01.18.576337 — neuroscience — Posted on 2024-01-21

1813 Prefrontal Cortex Neural Correlates of the Contraction Bias in Frequency Discrimination

Serrano-Fernandez, L.; Beiran, M.; Romo, R.; Parga, N.

10.1101/2023.07.27.550794 — neuroscience — Posted on 2024-01-21

1814 Phenotypic Plasticity of Symbiotic Organ Highlight Deep-sea Mussel as Model Species in Monitoring Exploitation of Deep-sea Methane Hydrate

Li, M.; Chen, H.; Wang, M.; Zhong, Z.; Lian, C.; Zhou, L.; Zhang, H.; Wang, H.; Cao, L.; Li, C.

10.1101/2022.08.11.503589 — ecology — Posted on 2024-01-21

1815 An infection and pathogenesis mouse model of SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR)

Wei, L.; Liu, S.; Lu, S.; Luo, S.; An, X.; Fan, H.; Chen, W.; Li, E.; Tong, Y.; Song, L.

10.1101/2024.01.03.574008 — microbiology — Posted on 2024-01-21

1816 Gaining Biological Insights through Supervised Data Visualization

Rhodes, J. S.; Aumon, A.; Morin, S.; Girard, M.; Larochelle, C.; Brunet-Ratnasingham, E.; Pagliuzza, A.; Machitto, L.; Zhang, W.; Cutler, A.; Grand'Maison, F.; Zhou, A.; Finzi, A.; Chomont, N.; Kaufmann, D. E.; Zandee, S.; Prat, A.; Wolf, G.; Moon, K. R.

10.1101/2023.11.22.568384 — bioinformatics — Posted on 2024-01-21

1817 Higher-order epistasis within Pol II trigger loop haplotypes

Duan, B.; Qiu, C.; Lockless, S. W.; Sze, S.-H.; Kaplan, C. D.

10.1101/2024.01.20.576280 — genetics — Posted on 2024-01-21

1818 Microbial Community Structure of an Anaerobic Side-stream Coupled Anoxic-aerobic Membrane Bioreactor (AOMBR-ASSR) for an In-situ Sludge Reduction Process

Xinqiang, N.; Jialun, H.; Jiao, Y.; Tang, T.; Bin, Z.

10.1101/2024.01.20.576432 — microbiology — Posted on 2024-01-21

1819 Viroid-like colonists of human microbiomes

Zheludev, I. N.; Edgar, R. C.; Galiano, M. J. L.; De la Pena, M.; Babaian, A.; Bhatt, A. S.; Fire, A. Z.

10.1101/2024.01.20.576352 — microbiology — Posted on 2024-01-21

1820 Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans

Araujo, A.; Dekker, J. D.; Garrison, K.; Su, Z.; Rhee, C.; Hu, Z.; Lee, B.-K.; Osorio, D.; Lee, J.; Iyer, V. R.; Ehrlich, L. I. R.; Georgiou, G.; Ippolito, G. C.; Yi, S.; Tucker, H. O.

10.1101/310680 — immunology — Posted on 2024-01-21

1821 DNA Damage Accelerates G-Quadruplex Folding in a Duplex-G-Quadruplex-Duplex Context

Fleming, A. M.; Jenkins, B. L. G. C.; Buck, B. A.; Burrows, C. J.

10.1101/2024.01.20.576387 — biochemistry — Posted on 2024-01-21

1822 Lifespan regulation by targeting heme signaling in yeast

Praveen, P. K.; Nady, N.; Barlit, H.; Gulhan, A.; Labunskyy, V. M.

10.1101/2024.01.20.576446 — biochemistry — Posted on 2024-01-21

1823 ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation

Ali, E. M.; Loy, C.; Trader, D. J.

10.1101/2024.01.20.576376 — biochemistry — Posted on 2024-01-21

1824 Microbial diversity and ecological complexity emerging from environmental variation and horizontal gene transfer in a simple mathematical model.

Babajanyan, S. G.; Garushyants, S. K.; Wolf, Y. I.; Koonin, E. V.

10.1101/2024.01.17.576128 — evolutionary biology — Posted on 2024-01-21

1825 Multipad Agarose Plate (MAP): A Rapid and High-Throughput Approach for Antibiotic Susceptibility Testing

Kals, M.; Mancini, L.; Kotar, J.; Donald, A.; Cicuta, P.

10.1101/2024.01.20.576355 — microbiology — Posted on 2024-01-21

1826 Deciphering the Rhythmic Symphony of Speech: A Neural Framework for Robust and Time-Invariant Speech Comprehension

Dogonasheva, O.; Zakharov, D.; Giraud, A.-L.; Gutkin, B.

10.1101/2024.01.17.575994 — neuroscience — Posted on 2024-01-21

Kurochkina, N. S.; Orlova, M. A.; Vigovskiy, M. A.; Zgoda, V. G.; Vepkhvadze, T. F.; Vavilov, N. E.; Makhnovskii, P. A.; Grigorieva, O. A.; Boroday, Y. R.; Philippov, V. V.; Lednev, E. M.; Efimenko, A. Y.; Popov, D. V.

10.1101/2023.12.01.569524 — physiology — Posted on 2024-01-21

1828 Developing folate-conjugated miR-34a therapeutic for prostate cancer treatment: Challenges and promises

Li, W.; Wang, Y.; Liu, X.; Wu, S.; Wang, M.; Turowski, S. G.; Spernyak, J. A.; Tracz, A.; Abdelaal, A. M.; Sudarshan, K.; Puzanov, I.; Chatta, G.; Kasinski, A. L.; Tang, D. G.

10.1101/2023.11.25.568612 — cancer biology — Posted on 2024-01-21

1829 Sequence-Dependent Material Properties of Biomolecular Condensates and their Relation to Dilute Phase Conformations

Devarajan, D. S.; Wang, J.; Szała-Mendyk, B.; Rekhi, S.; Nikoubashman, A.; Kim, Y. C.; Mittal, J.

10.1101/2023.05.09.540038 — biophysics — Posted on 2024-01-21

1830 Capturing G protein-coupled receptors into native lipid-bilayer nanodiscs using new diisobutylene/maleic acid (DIBMA) copolymers

Chu, C.; Vargas, C.; Barbosa, M. C.; Sommerhage, S.; Schroeder, G. F.; Keller, S.; Etzkorn, M.

10.1101/2024.01.20.576420 — biochemistry — Posted on 2024-01-21

1831 Lecanemab Blocks the Effects of the Aβ/Fibrinogen Complex on Blood Clots and Synapse Toxicity in Organotypic Culture

Singh, P. K.; Simoes-Pires, E. N.; Chen, Z.-L.; Torrente, D.; Calvano, M.; Sharma, A.; Strickland, S.; Norris, E. H.

10.1101/2024.01.20.576458 — biochemistry — Posted on 2024-01-21

1832 Dissociable encoding of motivated behavior by parallel thalamo-striatal projections

Beas, S.; Khan, I.; Gao, C.; Loewinger, G.; Macdonald, E.; Bashford, A.; Rodriguez-Gonzalez, S.; Pereira, F.; Penzo, M.

10.1101/2023.07.07.548113 — animal behavior and cognition — Posted on 2024-01-21

1833 Histone deacetylases regulate organ-specific growth in a horned beetle

Hu, Y.; Crabtree, J. R.; Macagno, A. L. M.; Moczek, A. P.

10.1101/2023.11.30.569342 — evolutionary biology — Posted on 2024-01-21

1834 Skeletal Muscle Stem Cells Modulate Niche Function in Duchenne Muscular Dystrophy through YY1-CCL5 Axis

Li, Y.; Li, C.; Sun, Q.; Chen, F.; Cheung, Y.; Zhao, Y.; Xie, T.; Chazaud, B.; Sun, H.; Wang, H.

10.1101/2024.01.13.575317 — cell biology — Posted on 2024-01-21

1835 Microplastics from disposable paper cups are enriched in the placenta and fetus, leading to metabolic and reproductive toxicity during pregnancy

Chen, Q.; Peng, C.; Xu, H.; Su, Z.; Yilihan, G.; Wei, X.; Shen, Y.; Jiang, C.

10.1101/2024.01.20.576431 — molecular biology — Posted on 2024-01-21

1836 Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets

Bairos, J. A.; Njoku, U.; Zafar, M.; Akl, M. G.; Li, L.; Parlakgul, G.; Arruda, A. P.; Widenmaier, S. B.

10.1101/2024.01.20.576345 — molecular biology — Posted on 2024-01-21

1837 Trends of Plasmodium falciparum molecular markers associated with resistance to artemisinins and reduced susceptibility to lumefantrine in Mainland Tanzania from 2016 to 2021

Bakari, C.; Mandara, C. I.; Madebe, R. A.; Seth, M. D.; Ngasala, B.; Kamugisha, E.; Ahmed, M.; Francis, F.; Bushukatale, S.; Chiduo, M.; Makene, T.; Kabanywanyi, A.; Mahende, M. K.; Muro, F.; Mkude, S.; Mandike, R.; Molteni, F.; Chacky, F.; Bishanga, D.; Njau, R.; Warsame, M.; Kabula, B.; Nyinondi, S.; Talundzic, E.; Lucchi, N. W.; Venkatesan, M.; Moriarty, L. F.; Serbantez, N.; Kitojo, C.; Reaves, E. J.; Halsey, E. S.; Mohamed, A.; Udhayakumar, V.; Ishengoma, D. S.

10.1101/2024.01.18.576107 — molecular biology — Posted on 2024-01-21

1838 Navigating contradictions: Salmonella Typhimurium chemotactic responses to conflicting chemoeffector signals show parity with bacterial growth benefits

Gentry-Lear, Z.; Franco, K.; Shavlik, M.; Harms, M. J.; Baylink, A.

10.1101/2024.01.18.576330 — microbiology — Posted on 2024-01-21

1839 Novel, active, and uncultured hydrocarbon degrading microbes in the ocean

Howe, K. L.; Zaugg, J.; Mason, O. U.

10.1101/2024.01.20.576437 — microbiology — Posted on 2024-01-21

1840 Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells

Moore, K. M.; Pelletier, A.-N.; Lapp, S.; Metz, A.; Tharp, G. K.; Lee, M.; Bhasin, S. S.; Bhasin, M.; Sekaly, R.-P.; Bosinger, S. E.; Suthar, M. S.

10.1101/2024.01.19.576293 — microbiology — Posted on 2024-01-21

1841 Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling ImmuneResponses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

Ma, B.; Kamle, S.; Lee, C.-M.; Lee, J. H.; Yee, D. C.; Zhu, Z.; Silverman, E. K.; DeMeo, D.; Choi, A. M. K.; Lee, C. G.; Elias, J. A.

10.1101/2023.12.27.573478 — immunology — Posted on 2024-01-21

1842 A microphysiological system for parallelized morphological and electrophysiological read-out of 3D neuronal cell culture

Jones, P. D.; Molina-Martinez, B.; Niedworok, A.; Cesare, P.

10.1101/2023.11.06.565744 — neuroscience — Posted on 2024-01-21

1843 How a speaker herds the audience: Multi-brain neural convergence over time during naturalistic storytelling

Chang, C. H. C.; Nastase, S. A.; Hasson, U.

10.1101/2023.10.10.561803 — neuroscience — Posted on 2024-01-21

1844 Thermodynamic analog of integrate-and-fire neuronal networks by maximum entropy modelling

Simoes, T. d. S. A. d. N. S.; Filho, C. I. N. S.; Herrmann, H. J.; Junior, J. S. d. A.; de Arcangelis, L.

10.1101/2024.01.18.576167 — neuroscience — Posted on 2024-01-21

1845 Genomic relationships among diploid and polyploid species of the genus Ludwigia L. section Jussiaea using a combination of molecular cytogenetic, morphological, and crossing investigations

BARLOY, D.; Portillo-Lemus, L.; Krueger-Hadfield, S.; Huteau, V.; Coriton, O.

10.1101/2023.01.02.522458 — plant biology — Posted on 2024-01-21

1846 Transcription-induced active forces suppress chromatin motion

Shin, S.; Shi, G.; Cho, H. W.; Thirumalai, D.

10.1101/2022.04.30.490180 — biophysics — Posted on 2024-01-21

1847 Quantification of histone H1 subtypes using targeted proteomics.

Lopez-Gomez, J.; Villareal, L.; Andres, M.; Ponte, I.; Xicoy, B.; Zamora, L.; Vilaseca, M.; Roque, A.

10.1101/2024.01.20.576464 — biochemistry — Posted on 2024-01-21

1848 Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks

Lay, M. A.; Thompson, V. F.; Adelakun, A. D.; Schwartz, J. C.

10.1101/2024.01.20.576463 — biochemistry — Posted on 2024-01-21

1849 Behavioral sequences across multiple animal species in the wild share common structural features

10.1101/2024.01.20.576411 — animal behavior and cognition — Posted on 2024-01-21

1850 Comparative analysis of intragroup intermale relationships: A study of wild bonobos (Pan paniscus) in Wamba, Democratic Republic of Congo and chimpanzees (Pan troglodytes) in Kalinzu Forest Reserve, Uganda

Shibata, S.; Furuichi, T.

10.1101/2023.09.10.557020 — animal behavior and cognition — Posted on 2024-01-21

1851 Deep learning predicts DNA methylation regulatory variants in specific brain cell types and enhances fine mapping for brain disorders

Zhou, J.; Weinberger, D.; Han, S.

10.1101/2024.01.18.576319 — genetics — Posted on 2024-01-21

1852 The FinnBrain Multimodal Neonatal Template and Atlas Collection: T1, T2, and DTI brain templates, and accompanying cortical and subcortical atlases

Tuulari, J. J.; Rosberg, A.; Pulli, E. P.; Hashempour, N.; Ukharova, E.; Lidauer, K.; Jolly, A.; Luotonen, S.; Audah, H. K.; Vartiainen, E.; Bano, W.; Suuronen, I.; Wigley, I. L. C.; Fonov, V.; Collins, D. L.; Merisaari, H.; Karlsson, L.; Karlsson, H.; Lewis, J. D.

10.1101/2024.01.18.576325 — neuroscience — Posted on 2024-01-21

1853 Activational and organizational effects of sex hormones on hippocampal inhibition

Hernandez-Vivanco, A.; Montes-Mellado, A.; de la Vega Ruiz, R.; Azcoitia, I.; Mendez, P.

10.1101/2024.01.20.576232 — neuroscience — Posted on 2024-01-21

1854 Individual connectivity-based parcellations reflect functional properties of human auditory cortex

Hakonen, M.; Dahmani, L.; Lankinen, K.; Ren, J.; Barbaro, J.; Blazejewska, A.; Cui, W.; Kotlarz, P.; Li, M.; Polimeni, J.; Turpin, T.; Uluc, I.; Wang, D.; liu, h.; Ahveninen, J.

10.1101/2024.01.20.576475 — neuroscience — Posted on 2024-01-21

1855 Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development

Caccavano, A. P.; Kimmel, S.; Vlachos, A.; Mahadevan, V.; Kim, J. H.; Vargish, G.; Chittajallu, R.; London, E.; Yuan, X.; Hunt, S.; Eldridge, M. A. G.; Cummins, A. C.; Hines, B. E.; Plotnikova, A.; Mohanty, A.; Averbeck, B. B.; Zaghloul, K.; Dimidschstein, J.; Fishell, G.; Pelkey, K. A.; McBain, C. J.

10.1101/2024.01.20.576455 — neuroscience — Posted on 2024-01-21

1856 nf-core/airrflow: an adaptive immune receptor repertoire analysis workflow employing the Immcantation framework

10.1101/2024.01.18.576147 — bioinformatics — Posted on 2024-01-20

1857 Inhibition of glioblastoma cell proliferation and invasion by the choline-kinase inhibitor JAS239 varies with cell type and hypoxia

Kelly, C. L.; Wydrzynska, M.; Phelan, M. M.; Osharovich, S.; Delikatny, E. J.; See, V.; Poptani, H.

10.1101/2024.01.17.576078 — cancer biology — Posted on 2024-01-20

1858 miR-100 and miR-125b Contribute to Enhanced Growth and Invasiveness

Nelson, H. M.; Qu, S.; Chapman, S. N.; Luthcke, N. L.; Schuster, S. A.; Turnbull, L. A.; Shameer, M.; Guy, L. L.; Liu, X.; Corn, K. C.; Vickers, K. C.; Liu, Q.; Franklin, J. L.; Weaver, A.; Rafat, M.; Coffey, R. J.; Patton, J. G.

10.1101/2024.01.16.575716 — cancer biology — Posted on 2024-01-20

1859 Involvement of the cellular prion protein in seeding and spreading of sarkosyl-derived fractions of Alzheimer's disease in Prnp mutant mice and in the P301S transgenic tauopathy mice model

Sala-Jarque, J.; Gil, V.; Andres-Benito, P.; Lidon, L.; Yanac-Huertas, R. E.; Lopez-Leon, C. F.; Hernandez, F.; Avila, J.; Lanciego, J. L.; Soriano, J.; Nuvolone, M.; Aguzzi, A.; Gavin, R.; Ferrer, I.; del Rio, J. A.

10.1101/2024.01.20.576414 — neuroscience — Posted on 2024-01-20

1860 PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more

Baheux Blin, M.; Loreau, V.; Schnorrer, F.; Mangeol, P.

10.1101/2024.01.17.576053 — biophysics — Posted on 2024-01-20

1861 Epigenetic control of multiple genes with a single lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

Monteferrario, D.; David, M.; Tadi, S. K.; Zhou, Y.; Marchetti, I.; Jeanneau, C.; Saviane, G.; Dupont, C. F.; Martelli, A. E.; Truong, L.; Eshleman, J.; Ng, C.; Huston, M.; Davis, G. D.; Fontenot, J. D.; Reik, A.; de la Rosa, M.; Fenard, D.

10.1101/2024.01.17.576049 — bioengineering — Posted on 2024-01-20

1862 Effect of iris pigmentation of blue and brown eyed individuals with European ancestry on ability to see in low light conditions after a short-term dark adaption period.

Cain, F. E.; Yamaguchi, K.

10.1101/2024.01.17.576074 — evolutionary biology — Posted on 2024-01-20

1863 HUB-DT: A tool for unsupervised behavioural discovery and analysis

Lindsay, A. J.; Seamans, J. K.

10.1101/2024.01.08.574696 — neuroscience — Posted on 2024-01-20

1864 Mechanisms of gas sensing by internal sensory neurons in Drosophila larvae

Lu, S.; Qian, C. S.; Grueber, W. B.

10.1101/2024.01.20.576342 — neuroscience — Posted on 2024-01-20

1865 Generative artificial intelligence performs rudimentary structural biology modelling

Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.

10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-01-20

1866 A transient burst of mutations occurs during the normal development of yeast colonies

Agier, N.; Vittorelli, N.; Chaux, F.; Gillet-Markowska, A.; O'Donnell, S.; Fischer, G.; Delmas, S.

10.1101/2023.12.11.571082 — genetics — Posted on 2024-01-20

1867 The Small Tumor Antigen of Merkel Cell Polyomavirus Accomplishes Cellular Transformation by Uniquely Localizing to the Nucleus Despite the Absence of a Known Nuclear Localization Signal

Thevenin, K. R.; Tieche, I. S.; Di Benedetoo, C. E.; Schrager, M.; Dye, K. N.

10.1101/2023.11.28.569067 — microbiology — Posted on 2024-01-20

1868 Persistence and Free Chlorine Disinfection of Human Coronaviruses and Their Surrogates in Water

Zhang, M.; Leong, M.; Mitch, W.; Blish, C. A.; Boehm, A. B.

10.1101/2024.01.16.575911 — microbiology — Posted on 2024-01-20

1869 An unconventional regulatory circuitry involving Aurora B controls anaphase onset and error-free chromosome segregation in trypanosomes

Ballmer, D.; Lou, H. J.; Ishii, M.; Turk, B. E.; Akiyoshi, B.

10.1101/2024.01.20.576407 — cell biology — Posted on 2024-01-20

1870 DMD Human iPSC-derived skeletal muscle cells recapitulate selective calcium dysregulation pathways.

Delafenetre, A.; Chapotte-Baldacci, C.-A.; Doremus, L.; Massourides, E.; Bernard, M.; Regnacq, M.; Piquereau, J.; Chatelier, A.; Cognard, C.; Pinset, C.; Sebille, S.

10.1101/2024.01.20.576393 — cell biology — Posted on 2024-01-20

1871 OPA1 protects intervertebral disc and knee joint health in aged mice by maintaining the structure and metabolic functions of mitochondria

Madhu, V.; Hernandez-Meadows, M.; Coleman, A.; Sao, K.; Inguito, K.; Haslam, O.; Boneski, P. K.; Sesaki, H.; Collins, J. A.; Risbud, M. V.

10.1101/2024.01.17.576115 — cell biology — Posted on 2024-01-20

1872 Genetic modification of the bee parasite Crithidia bombi for improved visualization and protein localization

Bieber, B. V.; Lockett, S. G.; Glasser, S. K.; St. Clair, F. A.; Adler, L. S.; Povelones, M. L.

10.1101/2024.01.18.576273 — cell biology — Posted on 2024-01-20

1873 Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

Shinno, K.; Miura, Y.; Iijima, K. M.; Suzuki, E.; Ando, K.

10.1101/2024.01.20.576435 — cell biology — Posted on 2024-01-20

1874 Dermal wound healing contribution of aqueous extracts of Acalypha indica, Calotropis gigantea, Bacopa monnieri and their combination

S, B. O.; Tanimu, H.; ZIRMIRE, R.; Jamora, C.; Karthik, P.

10.1101/2024.01.18.576335 — cell biology — Posted on 2024-01-20

1875 FAP20 is required for flagellum assembly in Trypanosoma brucei

Shimogawa, M. M.; Jonnalagadda, K.; Hill, K.

10.1101/2024.01.19.576295 — cell biology — Posted on 2024-01-20

1876 Mechanism of Phosphate Release from Actin Filaments

Wang, Y.; Wu, J.; Zsolnay, V.; Pollard, T. D.; Voth, G. A.

10.1101/2023.08.03.551904 — biophysics — Posted on 2024-01-20

1877 Cytoneme-mediated intercellular signaling in keratinocytes essential for epidermal remodeling

Wang, Y.; He, Q.; Has, O.; Forouzesh, K.; Eom, D. S.

10.1101/2023.11.08.566303 — developmental biology — Posted on 2024-01-20

1878 Warming and altered precipitation independently and interactively suppress alpine soil microbial growth in a decadal-long experiment

Ruan, Y.; Ling, N.; Jiang, S.; Jing, X.; He, J.-S.; Shen, Q.; Nan, Z.

10.1101/2023.06.08.544195 — microbiology — Posted on 2024-01-20

1879 Evolutionarily conserved fMRI network dynamics in the mouse, macaque, and human brain

Gutierrez-Barragan, D.; Ramirez, J. S. B.; Panzeri, S.; Xu, T.; Gozzi, A.

10.1101/2023.07.19.549681 — neuroscience — Posted on 2024-01-20

1880 Pharmacological manipulations of the dorsomedial and dorsolateral striatum during fear extinction have opposing effects on fear renewal

Tanner, M. K.; Hohorst, A. A.; Westerman, J.; Sanchez Mendoza, C.; Han, R.; Moya, N. A.; Jaime, J.; Alvarez, L. M.; Balolia, A.; Abdul, R.; Dryden, M.; Loetz, E. C.; Greenwood, B. N.

10.1101/2024.01.17.576042 — neuroscience — Posted on 2024-01-20

1881 White Matter Microstructural Plasticity Associated with Educational Intervention in Reading Disability

Meisler, S. L.; Gabrieli, J. D. E.; Christodoulou, J. A.

10.1101/2023.08.31.553629 — neuroscience — Posted on 2024-01-20

1882 The proteome of agroinfiltrated Nicotiana benthamiana is shaped by extensive protein processing

Zheng, K.; Lyu, J.; Thomas, E.; Schuster, M.; Sanguankiattichai, N.; Ninck, S.; Kaschani, F.; Kaiser, M.; van der Hoorn, R. A. L.

10.1101/2023.11.02.565301 — plant biology — Posted on 2024-01-20

1883 Differential gene expression analysis of spatial transcriptomic experiments using spatial mixed models

Ospina, O. E.; Soupir, A. C.; Manjarres-Betancur, R.; Gonzalez-Calderon, G.; Yu, X.; Fridley, B. L.

10.1101/2024.01.20.576348 — bioinformatics — Posted on 2024-01-20

1884 Multiple Displacement Amplification Facilitates SMRT Sequencing of Microscopic Animals and the Genome of the Gastrotrich Lepidodermella squamata (Dujardin, 1841)

Roberts, N. G.; Gilmore, M. J.; Struck, T. H.; Kocot, K.

10.1101/2024.01.17.576123 — genomics — Posted on 2024-01-20

1885 CellDemux: coherent genetic demultiplexing in single-cell and single-nuclei experiments.

Zoodsma, M.; Zhan, Q.; Kumar, S.; Botey-Bataller, J.; Li, W.; Zhou, L.; Alaswad, A.; Liu, Z.; Zhang, Z.; Zhang, B.; Xu, C.-J.; Li, Y.

10.1101/2024.01.18.576186 — genomics — Posted on 2024-01-20

1886 The Rapidly Evolving X-linked miR-506 Family Finetunes Spermatogenesis to Enhance Sperm Competition

Wang, Z.; Wang, Y.; Zhou, T.; Chen, S.; Morris, D.; Magalhaes, R. D. M.; Li, M.; Wang, S.; Wang, H.; Xie, Y.; McSwiggin, H.; Oliver, D.; Yuan, S.; Zheng, H.; Mohammed, J.; Lai, E. C.; McCarrey, J. R.; Yan, W.

10.1101/2023.06.14.544876 — developmental biology — Posted on 2024-01-20

1887 Strategy for unlimited cycles of scarless oligonucleotide directed gene editing in Chlamydomonas reinhardtii

Ross, I. L.; Budiman, S.; Le, H. P.; Xiong, D.; Hemker, F.; Millen, E. A.; Oey, M.; Hankamer, B.

10.1101/2024.01.18.576255 — plant biology — Posted on 2024-01-20

1888 Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma

Czyzyk-Krzeska, M.; Bischoff, M. E.; Shamsaei, B.; Yang, J.; Secic, D.; Vemuri, B.; Reisz, J. A.; D'Alessandro, A.; Bartolacci, C.; Adamczyk, R.; Schmidt, L.; Wang, J.; Martines, A.; Biesiada, J.; Vest, K. E.; Scaglioni, P. P.; Plas, D. R.; Patra, K. C.; Gulati, S.; Figueroa, J. L.; Meller, J.; Cunningham, J. T.

10.1101/2024.01.16.575895 — cancer biology — Posted on 2024-01-20

1889 Therapeutic targeting of KRAS mutation-driven tumorigenesis by extracellular vesicles loaded with small interfering RNA

Zhai, Y.; Niu, S.; Qiu, T.; Yi, Y.; Yan, Y.; Hu, R.; He, X.; Xu, K.

10.1101/2024.01.17.576015 — cancer biology — Posted on 2024-01-20

1890 Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs

Drozdzyk, K.; Peter, M.; Dutzler, R.

10.1101/2024.01.18.576238 — biophysics — Posted on 2024-01-20

1891 Accurate inference of population history in the presence of background selection

Cousins, T.; Tabin, D.; Patterson, N.; Reich, D.; Durvasula, A.

10.1101/2024.01.18.576291 — genetics — Posted on 2024-01-20

1892 Structural insights into peptidoglycan hydrolysis by the FtsEX system in Escherichia coli during cell division

Li, J.; He, Y.; Xu, X.; Alcorlo, M.; Shi, J.; Roper, D. I.; A. Hermoso, J.; Sham, L.-T.; Luo, M.

10.1101/2024.01.16.575974 — microbiology — Posted on 2024-01-20

1893 CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunction

Mendes, N.; Zanesco, A.; Aguiar, C.; Rodrigues-Luiz, G. F.; Silva, D.; Campos, J.; Camara, N. O. S.; Moraes-Vieira, P.; Araujo, E.; Velloso, L. A.

10.1101/2024.01.16.575893 — neuroscience — Posted on 2024-01-20

1894 Retrieval of human aversive memories involves reactivation of gamma activity patterns in the hippocampus that originate in the amygdala during encoding

Costa, M.; Pacheco, D.; Gil-Nagel, A.; Toledano, R.; Imbach, L.; Sarnthein, J.; Strange, B.

10.1101/2024.01.18.576178 — neuroscience — Posted on 2024-01-20

1895 Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism

Yabut, K. C. B.; Martynova, A.; Nath, A.; Zercher, B. P.; Bush, M. F.; Isoherranen, N.

10.1101/2024.01.17.576032 — pharmacology and toxicology — Posted on 2024-01-20

1896 PI3 kinase inhibitor PI828 uncouples aminergic GPCRs and Ca2+ mobilization irrespectively of its primary target

Kotova, P. D.; Dymova, E. A.; Lyamin, O. O.; Rogachevskaja, O. A.; Kolesnikov, S. S.

10.1101/2024.01.17.576005 — pharmacology and toxicology — Posted on 2024-01-20

1897 Histological analysis of Scots pine (Pinus sylvestris L.) seedlings in response to root rot pathogen Heterobasidion annosum inoculation

Youssef, K.; Marttila, S.

10.1101/2024.01.17.576084 — pathology — Posted on 2024-01-20

1898 CPT1a regulates the delivery of extracellular fatty acids for cardiolipin turnover in prostate cancer cells.

Santiappillai, N. T.; Hakeem-Sanni, M. F.; Withy, A.; Butler, L. M.; Quek, L.-E.; Hoy, A. J.

10.1101/2024.01.16.575611 — cancer biology — Posted on 2024-01-20

1899 A comprehensive characterization of the viscoelastic properties of Bovine Submaxillary Mucin (BSM) and the effect of additives

Rulff, H.; Schmidt, R. F.; Wei, L.-F.; Fentker, K.; Kerkhoff, Y.; Mertins, P.; Mall, M. A.; Lauster, D.; Gradzielski, M.

10.1101/2024.01.17.576019 — biophysics — Posted on 2024-01-20

1900 Spectrally Resolved Localization Microscopy with Ultrahigh-Throughput

Batey, J. E.; Kim, G. W.; Yang, M.; Heffer, D. C.; Pott, E. D.; Giang, H.; Dong, B.

10.1101/2024.01.17.576082 — biophysics — Posted on 2024-01-20

1901 MetaCompare 2.0: Differential ranking of ecological and human health resistome risks

Rumi, M. A.; Oh, M.; Davis, B. C.; Juvekar, A.; Brown, C. L.; Vikesland, P.; Pruden, A.; ZHANG, L.

10.1101/2024.01.17.576132 — bioinformatics — Posted on 2024-01-20

1902 Layered entrenchment maintains essentiality in protein-protein interactions.

Schulz, L.; Zarzycki, J.; Steinchen, W.; Hochberg, G. K. A.; Erb, T. J.

10.1101/2024.01.18.576253 — biochemistry — Posted on 2024-01-20

1903 Estimation of Uncertainty and Location-specific Variation in Regional Food Web Interactions

Brothers, A. M.; Santillan, V.; Quitian, M.; Neuschultz, E. L.; Schleuning, M.; Böhning-Gaese, K.; Llamoza, O. A.; Thron, C.

10.1101/2024.01.17.575986 — ecology — Posted on 2024-01-20

1904 Ontogeny shapes individual specialization

Hertel, A. G.; Albrecht, J.; Selva, N.; Sergiel, A.; Hobson, K. A.; Janz, D. M.; Mulch, A.; Kindberg, J.; Hansen, J. E.; Frank, S. C.; Zedrosser, A.; Mueller, T.

10.1101/2023.04.17.537142 — ecology — Posted on 2024-01-20

1905 Development and patterning of a highly versatile visual system in spiders

Baudouin Gonzalez, L.; Schoenauer, A.; Harper, A.; Arif, S.; Leite, D. J.; Steinhoff, P. O. M.; Pechmann, M.; Telizhenko, V.; Pande, A.; Kosiol, C.; McGregor, A. P.; Sumner-Rooney, L.

10.1101/2023.12.22.572789 — developmental biology — Posted on 2024-01-20

1906 EasyGrid: A versatile platform for automated cryo-EM sample preparation and quality control

Gemin, O.; Armijo, V.; Hons, M.; Bissardon, C.; Linares, R.; Bowler, M. W.; Wolff, G.; Kovalev, K.; Babenko, A.; Salo, V. T.; Schneider, S.; Rossi, C.; Lecomte, L.; Deckers, T.; Lauzier, K.; Janocha, R.; Felisaz, F.; Sinoir, J.; Galej, W. P.; Mahamid, J.; Muller, C. W.; Eustermann, S.; Mattei, S.; Cipriani, F.; Papp, G.

10.1101/2024.01.18.576170 — molecular biology — Posted on 2024-01-20

1907 Acyltransferases in the first step of glycerophospholipid synthesis have redundant and non-redundant roles in sn-1 acyl chain regulation, ether lipid levels, and cell survival

Salame, S.; Qasmaoui, H.; Jose, G. P.; Fleuriot, L.; Debayle, D.; Harayama, T.

10.1101/2024.01.17.576130 — cell biology — Posted on 2024-01-20

1908 Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing

Huda, M. N.; Zimmermann, R.; Nagar, P.; Alam, J.; Islam, M. R.; Dayebgadoh, G.; Miah, M.; Kempf, C. G.; Thornton, J. L.; Hattem, G.; Gies, A. J.; Zhang, Y.; Wen, T.; BYRUM, S.; Rahman, M. A.; Florens, L.; Washburn, M.; Miah, S.

10.1101/2024.01.16.575949 — molecular biology — Posted on 2024-01-20

1909 Geometric changes in the nucleoids of Deinococcus radiodurans reveal involvement of new proteins in recovery from ionizing radiation.

Cordova, A.; Niese, B.; Sweet, P.; Kamat, P.; Phillip, J. M.; Gordon, V.; Contreras, L. M.

10.1101/2024.01.17.576117 — molecular biology — Posted on 2024-01-20

1910 Constitutive Plasma Membrane Turnover in T-REx293 cells via Ordered Membrane Domain Endocytosis under Mitochondrial Control

Deisl, C.; Moe, O. W.; Hilgemann, D. W.

10.1101/2024.01.17.576124 — cell biology — Posted on 2024-01-20

1911 Visualization of DNA Methylation in Cell Cycle Genes during iPSC Cardiac Differentiation

Li, N.; Nguyen, B. T.; Zhang, Z.; Zhang, Y.

10.1101/2024.01.17.575536 — cell biology — Posted on 2024-01-20

1912 Gravitational and mechanical forces drive mitochondrial translation

Wakigawa, T.; Kimura, Y.; Mito, M.; Tsubaki, T.; Lee, M.; Nakamura, K.; Khan, A. H.; Saito, H.; Yamamori, T.; Yamazaki, T.; Higashibata, A.; Tsuboi, T.; Hirabayashi, Y.; Takeuchi-Tomita, N.; Saito, T.; Higashitani, A.; Shichino, Y.; Iwasaki, S.

10.1101/2023.01.18.524628 — molecular biology — Posted on 2024-01-20

1913 Bitter taste receptor T2R14 and autophagy flux in gingival epithelial cells

Singh, N.; Ulmer, B.; Medapati, M.; Schroth, R.; Ghavami, S.; Chelikani, P.

10.1101/2024.01.17.576143 — cell biology — Posted on 2024-01-20

1914 CD62L-selected umbilical cord blood universal CAR T cells

Georgiadis, C.; Bor, L.; Syed, F.; Zhan, H.; Gkazi, S. A.; Etuk, A.; Abramowski-Mock, U.; Preece, R.; Cuber, P.; Adams, S.; Ottaviano, G.; QASIM, W.

10.1101/2024.01.18.576145 — molecular biology — Posted on 2024-01-20

1915 Retinal neuroanatomy of two emerging model organisms, the spiny mouse (Acomys dimidiatus) and the Mongolian gerbil (Meriones unguiculatus)

Bills, J. D.; Seifert, A. W.; Morris, A. C.

10.1101/2024.01.17.576137 — cell biology — Posted on 2024-01-20

1916 A Multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A.

Carrington, G.; Fatima, U.; Caramujo, I.; Lewis, T.; Casas-Mao, D.; Peckham, M.

10.1101/2024.01.18.576271 — cell biology — Posted on 2024-01-20

1917 High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes

Locke, T. M.; Fields, R.; Gizinski, H.; Otto, G. M.; Berg, M. D.; Villen, J.; Sancak, Y.; Schweppe, D. K.

10.1101/2024.01.18.575273 — cell biology — Posted on 2024-01-20

1918 Acceleration of HDL-mediated cellular cholesterol efflux alleviates periodontitis

Ryu, J.-h.; Tran, T.-T.; Lee, G.; Huh, Y. H.; Chung, K.-H.; Lee, S. Y.; Park, K. H.; Kook, M.-S.; Ryu, J.; Kim, O.-S.; Lim, H.-P.; Koh, J.-T.

10.1101/2024.01.18.576176 — cell biology — Posted on 2024-01-20

1919 Single-cell morphodynamical trajectories enable prediction of gene expression accompanying cell state change

Copperman, J.; McLean, I. C.; Gross, S. M.; Chang, Y. H.; Zuckerman, D. M.; Heiser, L. M.

10.1101/2024.01.18.576248 — cell biology — Posted on 2024-01-20

1920 In vivo rescue of arboviruses directly from subgenomic DNA fragments

Cochin, M.; Driouich, J.-S.; Moureau, G.; Piorkowski, G.; de Lamballerie, X. N.; Nougairede, A.

10.1101/2024.01.17.576038 — microbiology — Posted on 2024-01-20

1921 Sac1 links phosphoinositide turnover to cryptococcal virulence

Gaylord, E. A.; Choy, H. L.; Chen, G.; Briner, S. L.; Doering, T. L.

10.1101/2024.01.18.576303 — microbiology — Posted on 2024-01-20

1922 The Role of Rhizosphere Microorganisms and CNPS Genes in Shaping Nutritional Traits of Capsicum

Tao, Y.; Zhang, M.; Peng, S.; Long, S.; Zou, X.; Li, X.

10.1101/2024.01.17.575995 — microbiology — Posted on 2024-01-20

1923 Dietary tryptophan and genetic susceptibility expand gut microbiota that promote systemic autoimmune activation

Ma, L.; Ge, Y.; Brown, J.; Choi, S. C.; Elshikha, A.; Kanda, N.; Terrell, M.; Six, N.; Garcia, A.; Mohamadzadeh, M.; Silverman, G. J.; Morel, L.

10.1101/2024.01.16.575942 — immunology — Posted on 2024-01-20

1924 Discordant effects of ex-vivo JAK inhibition on inflammatory responses in colonic compared to ileal mucosa

Kaboub, K.; Abu-Taha, H.; Arrouasse, J.; Shaham-Barda, E.; Wasserberg, N.; Hayman-Manzur, L.; Friedenberg, A.; Levy-Barda, A.; Goren, I.; Yanai, H.; Levi, Z.; Banai-Eran, H.; Avni-Biron, I.; Ollech, J. E.; Cohen-Kedar, S.; Dotan, I.; Rabinowitz, K. M.

10.1101/2024.01.18.576013 — immunology — Posted on 2024-01-20

1925 Laying the Foundation: Modern Transformers for Gold-Standard Sleep Analysis

Coon, W. G.; Ogg, M.

10.1101/2024.01.18.576246 — neuroscience — Posted on 2024-01-20

1926 Counter-balancing X-linked Mecp2 hypofunction by hyperfunction ameliorates disease features in a model of Rett syndrome: implications for genetic therapies

McGraw, C. M.; Soriano, S.; Shuang, H.; Connolly, D. R.; Chahrour, A.; Wu, Z.; Liang, A. J.; Sun, Y.; Tang, J.; Samaco, R. C.

10.1101/2024.01.18.576265 — neuroscience — Posted on 2024-01-20

1927 Self-Supervised Transformer Model Training for a Sleep-EEG Foundation Model

Ogg, M.; Coon, W. G.

10.1101/2024.01.18.576245 — neuroscience — Posted on 2024-01-20

1928 Effects of High Fat Diet on Metabolic Health Vary by Age of Menopause Onset

Salinero, A. E.; Venkataganesh, H.; Abi Ghanem, C.; Riccio, D.; Kelly, R. D.; Gannon, O. J.; Sura, A.; Brooks, H. L.; Zuloaga, K. L.

10.1101/2024.01.18.576269 — neuroscience — Posted on 2024-01-20

1929 Claustrum projections to the anterior cingulate modulate nociceptive and pain-associated behaviour

Faig, C.; Kim, G.; Do, A.; Dworsky-Fried, Z.; Jackson, J.; Taylor, A. M. W.

10.1101/2024.01.18.576065 — neuroscience — Posted on 2024-01-20

1930 Protective Effects of Lipoxin A4 and B4 Signaling on the Inner Retina in a Mouse Model of Experimental Glaucoma

Liu, H.-H.; Cullen, P. F.; Sivak, J. M.; Gronert, K.; Flanagan, J. G.

10.1101/2024.01.17.575414 — neuroscience — Posted on 2024-01-20

1931 miRNA family miR-29 inhibits PINK1-PRKN dependent mitophagy via ATG9A

Markham, B. N.; Ramnarine, C.; Kim, S.; Grever, W. E.; Soto-Beasley, A. I.; Heckman, M.; Ren, Y.; Osborne, A. C.; Bhagwate, A. V.; Liu, Y.; Wang, C.; Kim, J.; Wszolek, Z. K.; Ross, O. A.; Springer, W.; Fiesel, F. C.

10.1101/2024.01.17.576122 — neuroscience — Posted on 2024-01-20

1932 Δ9-tetrahydrocannabinol (THC) Increases the Rewarding Value of Oxycodone During Self-Administration in Rats

Nguyen, J. D.; Grant, Y.; Yang, C.; Taffe, M. A.

10.1101/2024.01.18.576277 — neuroscience — Posted on 2024-01-20

1933 Heat Shock Proteins Function as Signaling Molecules to Mediate Neuron-Glia Communication During Aging

Wu, J.; Yang, O. J.; Soderblom, E. J.; Yan, D.

10.1101/2024.01.18.576052 — neuroscience — Posted on 2024-01-20

1934 Thermodynamic analog of integrate-and-fire neuronal networks by maximum entropy modelling

Simoes, T. d. S. A. d. N. S.; Filho, C. I. N. S.; Herrmann, H. J.; Junior, J. S. d. A.; de Arcangelis, L.

10.1101/2024.01.18.576167 — neuroscience — Posted on 2024-01-20

1935 Neurophysiological Correlates of Phase-Specific Enhancement of Motor Memory Consolidation via Slow-Wave Closed-Loop Targeted Memory Reactivation

Nicolas, J.; King, B. R.; Levesque, D.; Lazzouni, L.; Wang, D.; Grossman, N.; Swinnen, S. P.; Doyon, J.; Carrier, J.; Albouy, G.

10.1101/2024.01.16.575884 — neuroscience — Posted on 2024-01-20

1936 Dynamic connectivity profiles characteristic of conscious states are associated with enhanced conscious processing of external stimuli

Turker, B.; Manasova, D.; Beranger, B.; Naccache, L.; Sergent, C.; Sitt, J.

10.1101/2024.01.18.576171 — neuroscience — Posted on 2024-01-20

1937 The Calcitron: A Simple Neuron Model That Implements Many Learning Rules via the Calcium Control Hypothesis

Moldwin, T.; Segev, I.; Azran, L. S.

10.1101/2024.01.16.575890 — neuroscience — Posted on 2024-01-20

1938 Novel FKBP12 ligand promotes functional improvement in SOD1-G93A ALS mice

Moreno-Martinez, L.; Gaja-Capdevila, N.; Mosqueira-Martin, L.; Herrando-Grabulosa, M.; Gonzalez-Imaz, K.; Calvo, A. C.; Sagartzazu-Aizpurua, M.; Moreno-Garcia, L.; Fuentes, J. M.; Acevedo-Arozena, A.; Aizpurua, J. M.; Miranda, J. I.; Lopez de Munain, A.; Vallejo-Illarramendi, A.; Osta, R.; Navarro, X.; Gil-Bea, F. J.

10.1101/2024.01.17.576010 — neuroscience — Posted on 2024-01-20

1939 PYK2 in the dorsal striatum of Huntington disease R6/2 mouse model

al Massadi, O.; de Pins, B.; Longueville, S.; Giralt, A.; Irinopoulou, T.; Savariradjane, M.; Subashi, E.; Gines, S.; Caboche, J.; Betuing, S.; Girault, J.-A.

10.1101/2024.01.18.576195 — neuroscience — Posted on 2024-01-20

1940 Auditory Forward Masking Explained by a Subcortical Model with Efferent Control of Cochlear Gain

Maxwell, B. N.; Farhadi, A.; Brennan, M. H.; Svec, A.; Carney, L. H.

10.1101/2024.01.18.576173 — neuroscience — Posted on 2024-01-20

1941 A general theoretical framework unifying the adaptive, transient and sustained properties of ON and OFF auditory neural responses

Rancon, U.; Masquelier, T.; Cottereau, B. R.

10.1101/2024.01.17.576002 — neuroscience — Posted on 2024-01-20

1942 Deciphering the Molecular Mechanism of Post-Acute Sequelae of COVID-19 through Comorbidity Network Analysis

Tian, L.; Wong, I. C. K.; Zhang, Q.

10.1101/2024.01.17.575851 — pathology — Posted on 2024-01-20

1943 Acute adenoviral infection elicits an arrhythmogenic substrate prior to myocarditis

Padget, R. L.; Zeitz, M. J.; Blair, G. A.; Wu, X.; North, M. D.; Hoeker, G. S.; Stanley, K. E.; Phillips, C. M.; King, D. R.; Gourdie, R. G.; Tanenbaum, M. T.; Hoeker, G. S.; Swanger, S. A.; Poelzing, S.; Smyth, J. W.

10.1101/2022.11.29.518421 — pathology — Posted on 2024-01-20

1944 Claudin-4 modulates autophagy via SLC1A5/LAT1 as a tolerance mechanism for genomic instability in ovarian cancer.

R. Villagomez, F.; Lang, J.; Webb, P.; Neville, M.; Woodruff, E. R.; Bitler, B. G.

10.1101/2024.01.18.576263 — cancer biology — Posted on 2024-01-20

1945 Single cell RNA-sequencing of Ewing sarcoma tumors demonstrates transcriptional heterogeneity and clonal evolution.

Goodspeed, A.; Bodlak, A.; Nelson-Taylor, S.; Oike, N.; Shirai, R.; Walker, D.; Porfilio, T. E.; Treece, A.; Black, J. O.; Donaldson, N.; Cost, C.; Garrington, T.; Greffe, B.; Luna-Fineman, S.; Demedis, J.; Lake, J. A.; Danis, E.; Verneris, M. R.; Hayashi, M.

10.1101/2024.01.18.576251 — cancer biology — Posted on 2024-01-20

1946 Neural space-time model for dynamic scene recovery in multi-shot computational imaging systems

Cao, R.; Divekar, N. S.; Nunez, J.; Upadhyayula, S.; Waller, L.

10.1101/2024.01.16.575950 — biophysics — Posted on 2024-01-20

1947 How cancer-associated fibroblasts promote T cell exclusion in human lung tumors: a physical perspective

Ackermann, J.; Bernard, C.; Sirven, P.; Salmon, H.; Fraldi, M.; Ben Amar, M.

10.1101/2024.01.16.575824 — biophysics — Posted on 2024-01-20

1948 Binding profiles for 954 Drosophila and C. elegans transcription factors revealtissue specific regulatory relationships

Kudron, M.; Gewirtzman, L.; Victorsen, A.; Lear, B. C.; Gao, J.; Xu, J.; Samanta, S.; Frink, E.; Tran-Pearson, A.; Huynh, C.; Vafeados, D.; Hammonds, A.; FIsher, W.; Wall, M.; Wesseling, G.; Hernandez, V.; Lin, Z.; Kasparian, M.; White, K. P.; Allada, R.; Gerstein, M.; Hillier, L.; Celniker, S. E.; Reinke, V.; Waterston, R. H.

10.1101/2024.01.18.576242 — genomics — Posted on 2024-01-20

1949 Advancing Transcription Factor Binding Site Prediction Using DNA Breathing Dynamics and Sequence Transformers via Cross Attention

Kabir, A.; Bhattarai, M.; Rasmussen, K. O.; Shehu, A.; Bishop, A. R.; Alexandrov, B. S.; Usheva, A.

10.1101/2024.01.16.575935 — bioinformatics — Posted on 2024-01-20

1950 Gut microbiome carbon and sulfur metabolisms support Salmonella during pathogen infection

Leleiwi, I.; Kokkinias, K.; Kim, Y.; Baniasad, M.; Shaffer, M.; Sabag-Daigle, A.; Daly, R. A.; Flynn, R. M.; Wysocki, V. H.; Ahmer, B. M. M.; Borton, M. A.; Wrighton, K. C.

10.1101/2024.01.16.575907 — genomics — Posted on 2024-01-20

1951 Digital profiling of cancer transcriptomes from histology images with grouped vision attention

Zheng, Y.; Pizurica, M.; Carrillo-Perez, F.; Noor, H.; Yao, W.; Wohlfart, C.; Marchal, K.; Vladimirova, A.; Gevaert, O.

10.1101/2023.09.28.560068 — bioinformatics — Posted on 2024-01-20

1952 Characterization of non-monotonic relationships between tumor mutational burden and clinical outcomes

Anaya, J.; Kung, J.; Baras, A. S.

10.1101/2024.01.16.575937 — bioinformatics — Posted on 2024-01-20

1953 Spaceflight alters host-gut microbiota interactions

Gonzalez, E.; Lee, M. D.; Tierney, B. T.; Lipieta, N.; Flores, p.; Mishra, M.; Beckett, L.; Karouia, F.; Barker, R.; Jansen, R.; Green, S.; Weging, S.; Broddrick, J. T.; Singh, N. K.; Bezdan, D.; Galazka, J. M.; brereton, n. J.

10.1101/2024.01.18.576275 — genomics — Posted on 2024-01-20

1954 Microfluidic platform enables shear-less aerosolization of lipid nanoparticles for messenger RNA inhalation

Kim, J.; Jozic', A.; Bloom, E.; Jones, B.; Marra, M.; Murthy, N. T. V.; Eygeris, Y.; Sahay, G.

10.1101/2024.01.17.576136 — bioengineering — Posted on 2024-01-20

1955 The neocortical infrastructure for language involves region-specific patterns of laminar gene expression

Wong, M. M. K.; Sha, Z.; Lutje, L.; Kong, X.-Z.; Velthuijs, N.; van Heukelum, S.; van de Berg, W. D. J.; Jonkman, L. E.; Fisher, S. E.; Francks, C.

10.1101/2024.01.17.575815 — genetics — Posted on 2024-01-20

1956 Dorsal horn dendrite polarization during Spinal Cord Stimulation (SCS) predicted using the quasi-uniform-mirror assumption.

Zannou, A. L.; Belali Koochesfahani, M.; Russo, M.; Bikson, M.

10.1101/2024.01.17.575924 — bioengineering — Posted on 2024-01-20

1957 Diencephalic and Neuropeptidergic Dysfunction in Zebrafish with Autism Risk Mutations

Capps, M. E. S.; Moyer, A. J.; Conklin, C. L.; Martina, V.; Torija-Olson, E. G.; Klein, M. C.; Gannaway, W. C.; Calhoun, C. C. S.; Vivian, M. D.; Thyme, S. B.

10.1101/2024.01.18.576309 — genetics — Posted on 2024-01-20

1958 Using variable data independent acquisition for capillary electrophoresis-based untargeted metabolomics

Kiuchi, S.; Otoguro, Y.; Nitta, T.; Chung, M. H.; Nakaya, T.; Oobuchi, K.; Sasaki, K.; Yamamoto, H.; Tsugawa, H.

10.1101/2024.01.17.576157 — biochemistry — Posted on 2024-01-20

1959 Genome-wide allele frequency changes reveal that dynamic metapopulations evolve differently

Angst, P.; Haag, C. R.; Ben-Ami, F.; Fields, P. D.; Ebert, D.

10.1101/2024.01.18.575980 — evolutionary biology — Posted on 2024-01-20

1960 Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

Kroupova, A.; Spiteri, V. A.; Furihata, H.; Darren, D.; Ramachandran, S.; Rutter, Z.; Chakraborti, S.; Haubrich, K.; Pethe, J.; Gonzales, D.; Wijaya, A.; Rodriguez-Rios, M.; Lynch, D. M.; Farnaby, W.; Nakasone, M.; Zollman, D.; Ciulli, A.

10.1101/2024.01.17.575503 — biochemistry — Posted on 2024-01-20

1961 Signatures of adaptation at key insecticide resistance loci in Anopheles gambiae in Southern Ghana revealed by low-coverage WGS.

Dennis, T. P. W.; Essandoh, J.; Mable, B. K.; Viana, M.; Egyir-Yawson, A.; Weetman, D.

10.1101/2024.01.17.575856 — evolutionary biology — Posted on 2024-01-20

1962 In-Depth Mapping of DNA-PKcs Signaling Uncovers Conserved Features of Its Kinase Specificity

Marshall, S.; Navarro, M.; Ascencao, C.; Smolka, M. B.

10.1101/2024.01.17.576037 — biochemistry — Posted on 2024-01-20

1963 Plastid phylogenomics and cytonuclear discordance in Rubioideae, Rubiaceae

Thureborn, O.; Wikstrom, N.; Razafimandimbison, S. G.; Rydin, C.

10.1101/2024.01.17.576054 — evolutionary biology — Posted on 2024-01-20

1964 Niche partitioning in a cyanobacterium through divergence of its novel chlorophyll d-based light-harvesting system

Ulrich, N. J.; Shen, G.; Bryant, D. A.; Miller, S. R.

10.1101/2024.01.17.576076 — evolutionary biology — Posted on 2024-01-20

1965 DAMM for the detection and tracking of multiple animals within complex social and environmental settings

Kaul, G.; McDevitt, J.; Johnson, J.; Eban-Rothschild, A.

10.1101/2024.01.18.576153 — animal behavior and cognition — Posted on 2024-01-20

1966 Structural Insights into the DNA-Binding Mechanism of BCL11A: The Integral Role of ZnF6

Viennet, T.; Yin, M.; Jayaraj, A.; Kim, W.; Sun, Z.-Y. J.; Fujiwara, Y.; Zhang, K.; Seruggia, D.; Seo, H.-S.; Dhe-Paganon, S.; Orkin, S. H.; Arthanari, H.

10.1101/2024.01.17.576058 — molecular biology — Posted on 2024-01-20

1967 Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids

Boman, J.; Qvarnstrom, A.; Mugal, C. F.

10.1101/2024.01.18.576185 — evolutionary biology — Posted on 2024-01-20

1968 Negative allosteric modulation of CB1 cannabinoid receptor signaling decreases intravenous morphine self-administration and relapse in mice

Oliva, I.; Kazi, F. A.; Cantwell, L. N.; Thakur, G. A.; Crystal, J. D.; Hohmann, A. G.

10.1101/2024.01.16.575900 — animal behavior and cognition — Posted on 2024-01-20

1969 RAN translation of C9ORF72-related dipeptide repeat proteins recapitulates hallmarks of motor neurone disease and identifies hypothermia as a therapeutic strategy in zebrafish

Burrows, D. J.; McGown, A.; Abduljabbar, O.; Castelli, L. M.; Hautbergue, G. M.; Ramesh, T. M.

10.1101/2024.01.17.576077 — molecular biology — Posted on 2024-01-20

1970 Development of immobilized antibody-based affinity grid strategy and application in on-grid purification of target proteins for high-resolution cryo-EM

Zhao, Q.; Hong, X.; Wang, Y.; Zhang, S.; Ding, Z.; Meng, X.; Song, Q.; Hong, Q.; Jiang, W.; Shi, X.; Cai, T.; Cong, Y.

10.1101/2024.01.17.575977 — molecular biology — Posted on 2024-01-20

1971 A novel glutathione peroxidase-based biosensor disentangles differential subcellular accumulation of H2O2 and lipid hydroperoxides

Exposito-Rodriguez, M.; Reeder, B.; Brooke, G. N.; Hough, M. A.; Laissue, P. P.; Mullineaux, P. M.

10.1101/2024.01.18.576236 — molecular biology — Posted on 2024-01-20

1972 Non-linear growth-temperature relationship leads toopposite responses to warming in cold versus warmpopulations

Lindmark, M.; Ohlberger, J.; Gardmark, A.

10.1101/2024.01.17.575983 — ecology — Posted on 2024-01-20

1973 Fructose vs. Glucose: Modulating Stem Cell Growth and Function Through Sugar Supplementation

Elsaid, S.; Wu, X.; Tee, S. S.

10.1101/2024.01.18.576243 — molecular biology — Posted on 2024-01-20

1974 Mountain pine beetle spread in forests with varying host resistance

Brush, M.; Lewis, M. A.

10.1101/2024.01.17.575462 — ecology — Posted on 2024-01-20

1975 Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced diastolic dysfunction

Ardehali, H.; Tatekoshi, Y.; Chen, C.; Shapiro, J. S.; Chang, H.-C.; Blancard, M.; Burridge, P. W.; Feinstein, M.; D'Aquila, R.; Hsue, P.

10.1101/2024.01.17.575991 — molecular biology — Posted on 2024-01-20

1976 Changes in microglia chromatin accessibility in aged female mice.

Ansere, V. A.; Tooley, K. B.; Srividya, K.; Hoolehan, W.; Pham, K. D.; Ocanas, S. R.; Freeman, W. M.

10.1101/2024.01.18.575944 — molecular biology — Posted on 2024-01-20

1977 Genetic architecture of heritable leaf microbes

Boyle, J. A.; Frederickson, M. E.; Stinchcombe, J. R.

10.1101/2024.01.17.576069 — ecology — Posted on 2024-01-20

1978 Apical cell expansion maintained by Dusky-like establishes a scaffold for corneal lens morphogenesis

Ghosh, N.; Treisman, J. E.

10.1101/2024.01.17.575959 — developmental biology — Posted on 2024-01-20

1979 Fluorescent tools for the standardized work in Gram-negative bacteria

Delgadillo-Guevara, M.; Halte, M.; Erhardt, M.; Popp, P. F.

10.1101/2024.01.18.576257 — microbiology — Posted on 2024-01-20

1980 Human promoter CpG islands contain primate-specific repeats, cluster and resist reprogramming

Chaillet, J. R.; Mohan, K. N.; Anne, A.; Kumar, L.

10.1101/2024.01.17.576070 — developmental biology — Posted on 2024-01-20

1981 Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization

Fukumoto, J.; Yoshida, M.; Tokuoka, S. M.; Hayakawa, E. S. H.; Miyazaki, S.; Sakura, T.; Ken Inaoka, D.; Kita, K.; Usukura, J.; Shindou, H.; Tokumasu, F.

10.1101/2024.01.13.575495 — microbiology — Posted on 2024-01-20

1982 Ascidian embryonic cells with properties of neural-crest cells and neuromesodermal progenitors of vertebrates

Ishida, T.; Satou, Y.

10.1101/2023.05.24.542044 — developmental biology — Posted on 2024-01-20

1983 Diurnal rhythmicity of fecal microbiota and metabolite profiles in the first year of life: a randomized controlled interventional trial with infant formula

Heppner, N.; Reitmeier, S.; Heddes, M.; Vig Merino, M.; Schwartz, L.; Dietrich, A.; List, M.; Gigl, M.; Meng, C.; Omer, H.; Kleigrewe, K.; van der Veen, D. R.; Schirmer, M.; Kiessling, S.; Haller, D.

10.1101/2023.10.19.563092 — microbiology — Posted on 2024-01-20

1984 Multiple intersecting pathways are involved in the phosphorylation of CPEB1 to activate translation during mouse oocyte meiosis

Kunitomi, C.; Romero, M.; Daldello, E. M.; Schindler, K.; Conti, M.

10.1101/2024.01.17.575938 — developmental biology — Posted on 2024-01-20

1985 Efficacy of auxin-inducible protein degradation in C. elegans tissues using different auxins and TIR1-expressing strains

Sharma, N.; Marques, F.; Kratsios, P.

10.1101/2024.01.16.575916 — developmental biology — Posted on 2024-01-20

1986 Evaluation of the potential food allergy risks of recombinant human lactoferrin expressed in Komagataella phaffii

Anaya, Y.; Rosario Martinez, R.; Goodman, R. E.; Johnson, P.; Vajpeyi, S.; Lu, X.; Peterson, R.; Weyers, S. M.; Breen, B.; Newsham, K.; Scottoline, B.; Clark, A. J.; Malinczak, C.-A.

10.1101/2024.01.18.576250 — immunology — Posted on 2024-01-20

1987 Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

Nishi, K.; Sakamaki, T.; Nagasaka, A.; Kao, K. S.; Sadaoka, K.; Asano, M.; Yamamoto, N.; Takaori-Kondo, A.; Miyanishi, M.

10.1101/2024.01.18.576239 — developmental biology — Posted on 2024-01-20

1988 Infant vocal category exploration as a foundation for speech development

Yoo, H.; Su, P. L.; Ramsay, G.; Long, H. L.; Bene, E. R.; Oller, D. K.

10.1101/2024.01.17.576142 — developmental biology — Posted on 2024-01-20

1989 Estrogen-related differences in antitumor immunity and the gut microbiome contribute to sexual dimorphism of colorectal cancer

Lattanzi, G.; Perillo, F.; Diaz Basabe, A.; Caridi, B.; Amoroso, C.; Baeri, A.; Cirrincione, E.; Ghidini, M.; Galassi, B.; Cassinotti, E.; Baldari, L.; Boni, L.; Vecchi, M.; Caprioli, F.; Facciotti, F.; Strati, F.

10.1101/2024.01.17.576009 — immunology — Posted on 2024-01-20

1990 Cardiovascular risk in ANCA-associated vasculitis: monocyte phenotyping reveals distinctive signatures between serological subsets

Vegting, Y.; Hanford, K. M.; Jongejan, A.; Gajadin, G. R.; Versloot, M.; van der Bom-Baylon, N. D.; Dekker, T.; Penne, E. L.; van der Heijden, J. W.; Houben, E.; Bemelman, F. J.; Neele, A. E.; Moerland, P. D.; Vogt, L.; Kroon, J.; Hilhorst, M. L.

10.1101/2024.01.16.575967 — immunology — Posted on 2024-01-20

1991 Neutrophil immune profile controls spinal cord regeneration in zebrafish

de Sena-Tomas, C.; Lameira, L.; Naique Taborda, P.; Laborde, A.; Orger, M. B.; de Oliveira, S.; Saude, L.

10.1101/2024.01.17.576035 — developmental biology — Posted on 2024-01-20

1992 The landscape of immune dysregulation in pediatric sepsis at a single-cell resolution

Alhamdan, F.; Koutsogiannaki, S.; Yuki, K.

10.1101/2024.01.17.576030 — immunology — Posted on 2024-01-20

1993 Shared Transcriptomic Signatures of Inflammaging Among Diverse Strains of Drosophila melanogaster

Zhou, L.

10.1101/2024.01.17.576061 — immunology — Posted on 2024-01-20

1994 A robust and inducible precise genome editing via an all-in-one prime editor in human pluripotent stem cells

Wu, Y.; Zhong, A.; Sidharta, M.; Kim, T. W.; Ramirez, B.; Persily, B.; Studer, L.; Zhou, T.

10.1101/2024.01.18.576233 — cell biology — Posted on 2024-01-20

1995 Acute exercise increases systemic kynurenine pathway metabolites and activates the AHR in human PBMCs

Joisten, N.; Walzik, D.; Schenk, A.; Metcalfe, A. J.; Belen, S.; Schaaf, K.; Jacko, D.; Gehlert, S.; Spiliopoulou, P.; Garzinsky, A.-M.; Thevis, M.; Rappelt, L.; Donath, L.; Meuth, S. G.; Bloch, W.; Zimmer, P.

10.1101/2024.01.17.576018 — immunology — Posted on 2024-01-20

1996 Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics

Liu, Y.; Yin, M.; Mao, X.; Wu, S.; Wei, S.; Heng, S.; Yang, Y.; Huang, J.; Guo, Z.; Li, C.; Ji, C.; Hu, L.; Liu, W.; Zhang, L.-j.

10.1101/2024.01.16.575925 — immunology — Posted on 2024-01-20

1997 Multi-faceted roles of β-arrestins in G protein-coupled receptors endocytosis

Liu, J.; Xue, L.; Ravier, M.; Inoue, A.; Drube, J.; Hoffmann, C.; Trinquet, E.; Dupuis, E.; Prezeau, L.; Pin, J.-P.; Rondard, P.

10.1101/2024.01.18.576020 — cell biology — Posted on 2024-01-20

1998 Low-frequency ERK and Akt activity dynamics are predictive of stochastic cell division events

Bennett, J. J. R.; Stern, A. D.; Zhang, X.; Birtwistle, M. R.; Pandey, G.

10.1101/2024.01.17.576041 — cell biology — Posted on 2024-01-20

1999 Efficient 3D cone trajectory design for improved combined angiographic and perfusion imaging using arterial spin labeling

Shen, Q.; Wu, W.; Chiew, M.; Ji, Y.; Woods, J.; Okell, T. W.

10.1101/2024.01.17.576043 — neuroscience — Posted on 2024-01-20

2000 PbrSYP71 regulates ER accumulation by interacting with actin during pollen tube growth in Pyrus

Zhang, M.; Zhang, N.; Tang, C.; Qian, M.; sun, m.; liu, z.; xie, z.; Zhang, H.; Liu, Z.; Zhang, S.; Wang, P.; Wu, J.

10.1101/2024.01.17.576111 — cell biology — Posted on 2024-01-20

2001 Modular Phoneme Processing in Human Superior Temporal Gyrus

Cleary, D. R.; Tchoe, Y.; Bourhis, A.; Dickey, C.; Stedelin, B.; Ganji, M.; Lee, S. H.; Lee, J.; Siler, D.; Brown, E. C.; Rosen, B. Q.; Kaestner, E. J.; Yang, J. C.; Soper, D. J.; Han, S. J.; Paulk, A. C.; Cash, S. S.; Raslan, A. M.; Dayeh, S. A.; Halgren, E.

10.1101/2024.01.17.576120 — neuroscience — Posted on 2024-01-20

2002 Deciphering the Rhythmic Symphony of Speech: A Neural Framework for Robust and Time-Invariant Speech Comprehension

Dogonasheva, O.; Zakharov, D.; Giraud, A.-L.; Gutkin, B.

10.1101/2024.01.17.575994 — neuroscience — Posted on 2024-01-20

2003 Functional connectivity, tissue microstructure and T2 at 11.1 Tesla distinguishes neuroadaptive differences in two traumatic brain injury models in rats: A Translational Outcomes Project in NeuroTrauma (TOP-NT) UG3 phase study

Kommireddy, R. S.; Mehra, S.; Pompilus, M.; Arja, R. D.; Zhu, T.; Yang, Z.; Fu, Y.; Zhu, J.; Kobeissy, F.; Wang, K. K. W.; Febo, M.

10.1101/2023.12.10.570975 — neuroscience — Posted on 2024-01-20

2004 Transfer functions for burst firing probability in a model neocortical pyramidal cell

Graham, B. P.; Kay, J. W.; Phillips, W. A.

10.1101/2024.01.16.575982 — neuroscience — Posted on 2024-01-20

2005 Pharmacological manipulations of the dorsomedial and dorsolateral striatum during fear extinction have opposing effects on fear renewal

Greenwood, B. N.; Tanner, M. K.; Hohorst, A. A.; Westerman, J.; Sanchez Mendoza, C.; Han, R.; Moya, N. A.; Jaime, J.; Alvarez, L. M.; Balolia, A.; Abdul, R.; Loetz, E. C.; Dryden, M.

10.1101/2024.01.17.576042 — neuroscience — Posted on 2024-01-20

2006 Cholinergic neuromodulation of prefrontal attractor dynamics controls performance in spatial working memory

Mahrach, A.; Bestue, D.; Qi, X.-l.; Constantinidis, C.; Compte, A.

10.1101/2024.01.17.576071 — neuroscience — Posted on 2024-01-20

2007 Differential and temporally dynamic involvement of primate amygdala nuclei in face animacy and reward information processing

Kuraoka, K.; Nakamura, K.

10.1101/2024.01.16.575972 — neuroscience — Posted on 2024-01-20

2008 It's all in the timing: Delayed feedback in autism may weaken predictive mechanisms during contour integration

Knight, E. J.; Altschuler, T. S.; Molholm, S.; Murphy, J. W.; Freedman, E. G.; Foxe, J. J.

10.1101/2024.01.16.575908 — neuroscience — Posted on 2024-01-20

2009 Differential Short-Term Facilitation Of Synaptic Inputs And Spike Transmission At The Retinocollicular Synapse In Vivo

Teh, K. L.; Dossi, E.; Rouach, N.; Sibille, J.; Kremkow, J.

10.1101/2024.01.17.576068 — neuroscience — Posted on 2024-01-20

2010 ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia

Granzotto, A.; McQuade, A.; Chadarevian, J. P.; Davtyan, H.; Sensi, S. L.; Parker, I.; Blurton-Jones, M.; Smith, I.

10.1101/2024.01.18.576126 — neuroscience — Posted on 2024-01-20

2011 Intranasally Administered EVs from hiPSC-derived NSCs Alter the Transcriptomic Profile of Activated Microglia and Conserve Brain Function in an Alzheimer's Model

Madhu, L. N.; Kodali, M.; Upadhya, R.; Rao, S.; Shuai, B.; Somayaji, Y.; Attaluri, S.; Kirmani, M.; Gupta, S.; Maness, N.; Rao, X.; Cai, J.; Shetty, A.

10.1101/2024.01.18.576313 — neuroscience — Posted on 2024-01-20

2012 Psilocybin biphasically modulates cortical and behavioral activity in mice

Brockett, A. T.; Francis, N. A.

10.1101/2024.01.18.576229 — neuroscience — Posted on 2024-01-20

2013 Altered physiological, affective, and functional connectivity responses to acute stress in patients with alcohol use disorder

Schwarze, Y.; Voges, J.; Schröder, A.; Dreessen, S.; Voss, O.; Krach, S.; Paulus, F. M.; Rademacher, L.

10.1101/2024.01.18.576207 — neuroscience — Posted on 2024-01-20

2014 DeepResBat: deep residual batch harmonization accounting for covariate distribution differences

An, L.; Zhang, C.; Wulan, N.; Zhang, S.; Chen, P.; Ji, F.; Ng, K. K.; Chen, C.; Zhou, J. H.; Yeo, B. T. T.; the Alzheimer's Disease Neuroimaging Initiative, ; the Australian Imaging Biomarkers and Lifestyle Study of Aging,

10.1101/2024.01.18.574145 — neuroscience — Posted on 2024-01-20

2015 Physiological JNK3 Concentrations Are Higher in Motor-related and Disease-implicated Brain Regions of C57BL6/J Mice

Godieva, V.; Sammoura, F.; Verrier Paz, S.; Han, Y.; Di Guida, V.; Rishel, M. J.; Richardson, J. R.; Chambers, J. W.

10.1101/2024.01.17.575386 — neuroscience — Posted on 2024-01-20

2016 Spatially targeted inhibitory rhythms differentially affect neuronal integration

Headley, D.; Latimer, B.; Aberbach, A.; Nair, S. S.

10.1101/2024.01.17.576048 — neuroscience — Posted on 2024-01-20

2017 Energy Optimization Induces Predictive-coding Properties in a Multicompartment Spiking Neural Network Model

Zhang, M.; Bohte, S.

10.1101/2024.01.17.575877 — neuroscience — Posted on 2024-01-20

2018 Sensory choices as logistic classification

Carandini, M.

10.1101/2024.01.17.576029 — neuroscience — Posted on 2024-01-20

2019 Neural filtering of physiological tremor oscillations to spinal motor neurons mediates short-term acquisition of a skill learning task

Cabral, H. V.; Cudicio, A.; Bonardi, A.; Del Vecchio, A.; Falciati, L.; Orizio, C.; Martinez-Valdes, E.; Negro, F.

10.1101/2023.07.20.549840 — neuroscience — Posted on 2024-01-20

2020 Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia

Ardaya, M.; Tiveron, M.-C.; Cremer, H.; Dehay, B.; Perez-Cerda, F.; Matute, C.; Soria, F. N.; Cavaliere, F.

10.1101/2023.12.30.573719 — neuroscience — Posted on 2024-01-20

2021 Single and Multi-Site Cortical Stimulation Related to Human Sensorimotor Function

Ryun, S.; Chung, C. K.

10.1101/2024.01.18.574786 — neuroscience — Posted on 2024-01-20

2022 The type of inhibition provided by thalamic interneurons alters the input selectivity of thalamocortical neurons.

Djama, D.; Zirpel, F.; Ye, Z.; Moore, G.; Chue, C.; Edge, C.; Jager, P.; Delogu, A.; Brickley, S. G.

10.1101/2024.01.17.576001 — neuroscience — Posted on 2024-01-20

2023 Gut Analysis Toolbox: Automating quantitative analysis of enteric neurons

Sorensen, L.; Humenick, A.; Poon, S. S. B.; Han, M. N.; Mahdavian, N. S.; Hamnett, R.; Gomez-de-Mariscal, E.; Neckel, P. H.; Saito, A.; Mutunduwe, K.; Glennan, C.; Haase, R.; McQuade, R. M.; Foong, J. P. P.; Brookes, S. J. H.; Kaltschmidt, J. A.; Munoz-Barrutia, A.; King, S. K.; Veldhuis, N. A.; Carbone, S. E.; Poole, D. P.; Rajasekhar, P.

10.1101/2024.01.17.576140 — neuroscience — Posted on 2024-01-20

2024 A Cell Model for the Detection of a Planar Surface Using Motion Stereo in Area MST of the Visual Cortex

Kawakami, S.

10.1101/2024.01.16.575918 — neuroscience — Posted on 2024-01-20

2025 Emergence of neocortical function in heterotopic neurons

Roig-Puiggros, S.; Guyoton, M.; Suchkov, D.; Fortoul, A.; Fievre, S.; Matteucci, G.; Maino, E.; Foucher, C. G.; Fuciec, D.; Klingler, E.; Francis, F.; Minlebaev, M.; El-Boustani, S.; Watrin, F.; Manent, J.-B.; Jabaudon, D.

10.1101/2024.01.17.576031 — neuroscience — Posted on 2024-01-20

2026 Reduced recruitment of inhibitory control regions in very young children with ADHD during a modified Kiddie Continuous Performance Task: a fMRI study.

Bayat, M.; Hernandez, M.; Curzon, M.; Garic, D.; Graziano, P.; Dick, A. S.

10.1101/2024.01.17.576033 — neuroscience — Posted on 2024-01-20

2027 PINK1 knockout rats show premotor cognitive deficits measured through a complex maze

Soto, I.; Nejtek, V.; Siderovksi, D.; Salvatore, M. F.

10.1101/2024.01.18.576285 — neuroscience — Posted on 2024-01-20

2028 A birds-eye view: exploration of the flavin-containing monooxygenase (FMO) superfamily in common wheat.

Sun, S.; Bakkeren, G.

10.1101/2024.01.16.575770 — plant biology — Posted on 2024-01-20

2029 A dynamic WUSCHEL / Layer 1 interplay directs shoot apical meristem formation during regeneration

Kumar, M.; Ayzenshtat, D.; Zemach, H.; Belausov, E.; Eshed-Williams, L.; Bocobza, S.

10.1101/2024.01.16.575947 — plant biology — Posted on 2024-01-20

2030 The unusual orf117Sha locus causes desynchronization of pollen development in the Arabidopsis gametophytic Sha CMS

Dehaene, N.; Boussardon, C.; Andrey, P.; Charif, D.; Brandt, D.; Gilouppe Taillefer, C.; Nietzel, T.; Ricou, A.; Simon, M.; Tran, J.; Vezon, D.; Camilleri, C.; Arimura, S.-i.; Schwarzländer, M.; Budar, F.

10.1101/2024.01.17.575984 — plant biology — Posted on 2024-01-20

2031 Identification of novel and distinct FGF23 signaling in a Klotho-dependent and -independent manner

Kopper, K.; Pastor, J.; Moe, O. W.; Loffing, J.; Pathare, G.

10.1101/2024.01.18.576116 — physiology — Posted on 2024-01-20

2032 Cell-autonomous and non-cell-autonomous effects of arginase-II on cardiac aging

Potenza, D. M.; Cheng, X.; AJALBERT, G.; Brenna, A.; Giraud, M.-N.; FROBERT, A.; Cook, S.; Mertz, K. D.; Yang, Z.; Ming, X.-F.

10.1101/2024.01.17.576017 — physiology — Posted on 2024-01-20

2033 Intestinal barrier function in the naked mole-rat: an emergent model for gastrointestinal insights

Aguilera-Lizarraga, J.; Ritoux, A.; Bulmer, D.; Smith, E. S. J.

10.1101/2024.01.17.576063 — physiology — Posted on 2024-01-20

2034 Discovery of Highly Active Kynureninases for Cancer Immunotherapy through Protein Language Model

Eom, H.; Cho, K. S.; Lee, J.; Kim, S.; Park, S.; Kim, H.; Yang, J.; Han, Y.-H.; Lee, J.; Seok, C.; Lee, M. S.; Song, W. J.; Steinegger, M.

10.1101/2024.01.16.575968 — cancer biology — Posted on 2024-01-20

2035 Pharmacogenomics Guided Spaceflight: the intersection between space-flown drugs and space genes

Nelson, T. M.; Rose, J. K.; Walter, C. E.; Cervantes-Navarro, G. L.; Schmidt, C. M.; Lin, R.; Alexander, E.; Zheng, J. T.; Glicksberg, B. S.; Schmidt, J. C.; Overbey, E.; Rana, B.; Patel, H.; Schmidt, M. A.; Mason, C. E.

10.1101/2024.01.16.575951 — pharmacology and toxicology — Posted on 2024-01-20

2036 Cell polarity proteins promote macropinocytosis in response to metabolic stress

Lambies, G.; Lee, S.-W.; Duong-Polk, K.; Aza-Blanc, P.; Maganti, S.; Dawson, D. W.; Commisso, C.

10.1101/2024.01.16.575943 — cancer biology — Posted on 2024-01-20

2037 Label-free biosensor assay decodes the dynamics of Toll-like receptor signaling

Holze, J.; Lauber, F.; Kostenis, E.; Weindl, G.

10.1101/2024.01.18.576268 — pharmacology and toxicology — Posted on 2024-01-20

2038 cis-MoO2(BHAN)2 COMPLEX: ITS ROLE IN THE PROTECTION OF RADIATION-INDUCED DNA DAMAGE

DEB, P.

10.1101/2024.01.17.576028 — cancer biology — Posted on 2024-01-20

2039 MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth

Cheng, O. J.; Lebish, E. J.; Jensen, O.; Jacenik, D.; Trivedi, S.; Cacioppo, J.; Aube, J.; Beswick, E. J.; Leung, D. T.

10.1101/2024.01.16.575894 — cancer biology — Posted on 2024-01-20

2040 TKI Type Switching Overcomes ROS1 L2086F in ROS1 Fusion-Positive Cancers

Thawani, R.; Repetto, M.; Keddy, C.; Nicholson, K.; Jones, K.; Nusser, K.; Beach, C. Z.; Harada, G.; Drilon, A.; Davare, M. A.

10.1101/2024.01.16.575901 — cancer biology — Posted on 2024-01-20

2041 Group A Streptococcal Collagen-like Protein 1 Restricts Tumor Growth in Murine Pancreatic Adenocarcinoma and Inhibits Cancer-Promoting Neutrophil Extracellular Traps

Henderson, E.; Ivey, A.; Choi, S. J.; Santiago, S.; McNitt, D.; Liu, T. W.; Lukomski, S.; Boone, B. A.

10.1101/2024.01.17.576060 — cancer biology — Posted on 2024-01-20

2042 Comparative analysis of kidney transplantation modeled using precision-cut kidney slices and kidney transplantation in pigs

Moor, M. B.; Nordström, J.; Burmakin, M.; Raki, M.; Al-Saad, S.; Nowak, G.; Wennberg, L.; Patrakka, J.; Olauson, H.

10.1101/2024.01.17.575664 — pathology — Posted on 2024-01-20

2043 Mitochondrially targeted deferasirox kills cancer cells via simultaneous iron deprivation and ferroptosis induction.

Jadhav, S. B.; Sandoval Acuna, C.; Pacior Pampin, Y.; Klanicova, K.; Blazkova, K.; Sedlacek, R.; Stursa, J.; Werner, L.; Truksa, J.

10.1101/2024.01.17.575692 — cancer biology — Posted on 2024-01-20

2044 Deep Learning Based Identification of Tissue of Origin for Carcinomas of Unknown Primary utilizing micro-RNA expression

Raghu, A.; Raghu, A.; Wise, J. F.

10.1101/2024.01.17.576064 — cancer biology — Posted on 2024-01-20

2045 ComboPath: An ML system for predicting drug combination effects with superior model specification

Ranasinghe, D. S.; Sanders, N. E.; Tam, H. H.; Liu, C.; Spitz, D.

10.1101/2024.01.16.575408 — biophysics — Posted on 2024-01-20

2046 Diffusion-limited cytokine signaling in T cell populations

Brunner, P.; Kiwitz, L.; Li, L.; Thurley, K.

10.1101/2024.01.18.576190 — biophysics — Posted on 2024-01-20

2047 Engineering CRBN for rapid identification of next generation binders

Bailey, H. J.; Eisert, J.; Vollrath, J.; Leibrock, E.-M.; Kondratov, I.; Matviyuk, T.; Tolmachova, N.; Langer, J. D.; Wegener, A. A.; Sorrell, F. J.; Dikic, I.

10.1101/2024.01.18.576231 — biophysics — Posted on 2024-01-20

2048 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers, tested on DNA plectoneme formation dynamics

Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.

10.1101/2024.01.18.576226 — biophysics — Posted on 2024-01-20

2049 Structure, motion, and multiscale search of traveling networks

Cira, N. J.; Paull, M. L.; Sinha, S.; Zanini, F.; Ma, E. Y.; Riedel-Kruse, I. H.

10.1101/2024.01.16.575883 — biophysics — Posted on 2024-01-20

2050 Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities

Takemon, Y.; Pleasance, E. D.; Gagliardi, A.; Hughes, C. S.; Csizmok, V.; Wee, K.; Trinh, D. L.; Huff, R. D.; Mungall, A. J.; Moore, R. A.; Chuah, E.; Mungall, K. L.; Lewis, E.; Nelson, J.; Lim, H. J.; Renouf, D. J.; Jones, S. J.; Laskin, J.; Marra, M.

10.1101/2024.01.17.575929 — bioinformatics — Posted on 2024-01-20

2051 FateNet: an integration of dynamical systems and deep learning for cell fate prediction

Sadria, M.; Bury, T.

10.1101/2024.01.16.575913 — bioinformatics — Posted on 2024-01-20

2052 Elucidating Resistance Mechanisms in Staphylococcus epidermidis: A High-Performing MALDI-TOF MS-Based Proteomic Approach for Predictive Modeling

Ren, M.; Chen, Q.; Zhang, J.

10.1101/2024.01.16.575876 — bioinformatics — Posted on 2024-01-20

2053 Toward subtask decomposition-based learning and benchmarking for genetic perturbation outcome prediction and beyond

Gao, Y.; Wei, Z.; Dong, K.; Yang, J.; Chuai, G.; Liu, Q.

10.1101/2024.01.17.576034 — bioinformatics — Posted on 2024-01-20

2054 Optical Fiber-Assisted Printing: A Platform Technology for Straightforward Photopolymer Resins Patterning and Freeform 3D Printing

Cianciosi, A.; Pfeiffle, M.; Wohlfahrt, P.; Nuernberger, S.; Jungst, T.

10.1101/2024.01.17.576081 — bioengineering — Posted on 2024-01-20

2055 Injury Severity is a Key Contributor to Coagulation Dysregulation and Fibrinogen Consumption

Gosselin, A. R.; Bargoud, C. G.; Sawalkar, A.; Mathew, S.; Toussaint, A.; Greenen, M.; Coyle, S. M.; Macor, M.; Krishnan, A. K.; Goswami, J.; Hanna, J. S.; Tutwiler, V.

10.1101/2024.01.16.575945 — bioengineering — Posted on 2024-01-20

2056 A fast and sensitive size-exclusion chromatography method for plasma extracellular vesicle proteomic analysis

Diaz Ludovico, I.; Powell, S. M.; Many, G.; Bramer, L.; Sarkar, S.; Stratton, K.; Liu, T.; Shi, T.; Qian, W.-J.; Burnum-Johnson, K. E.; Melchior, J. T.; Nakayasu, E. S.

10.1101/2024.01.17.576135 — biochemistry — Posted on 2024-01-20

2057 Expanding the ligandable proteome by paralog hopping with covalent probes

Zhang, Y.; Liu, Z.; Hirschi, M.; Brodsky, O.; Johnson, E.; Won, S. J.; Nagata, A.; Petroski, M. D.; Majmudar, J. D.; Niessen, S.; VanArsdale, T.; Gilbert, A. M.; Hayward, M. M.; Stewart, A. E.; Nager, A. R.; Melillo, B.; Cravatt, B. F.

10.1101/2024.01.18.576274 — biochemistry — Posted on 2024-01-20

2058 Effects of local and landscape factors on paddy field arthropod diversity: from species to communities

Ou, J.-A.; Huang, C.-L.; Chen, H.-J.; Tsai, C.-W.; Ho, C.-K.

10.1101/2024.01.17.575529 — ecology — Posted on 2024-01-20

2059 Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

Yamanaka, T.; Xiao, Z.; Tsujita, N.; Awad, M.; Umehara, T.; Shimada, M.

10.1101/2024.01.16.575926 — cell biology — Posted on 2024-01-20

2060 SHP2-triggered endothelium activation fuels estradiol-independent endometrial sterile inflammation

Pan, J.; Zhao, L.; Fang, W.; Zhai, L.; Tan, M.; Qu, J.; Xu, Q.; Du, Q.; Lv, W.; Sun, Y.

10.1101/2024.01.16.575960 — molecular biology — Posted on 2024-01-20

2061 The N-terminus of Plasmodium falciparum Circumsporozoite Protein Contains Three Non-Overlapping Murine B-cell Epitope Regions

Beutler, N.; Garcia, E.; Lai, Y.-C.; Ndihokubwayo, J.; Gambuzza, K.; Zhao, J.; Burton, D.; Rogers, T.

10.1101/2024.01.18.574923 — immunology — Posted on 2024-01-20

2062 FrameDiPT: SE(3) Diffusion Model for Protein Structure Inpainting

Zhang, C.; Leach, A.; Makkink, T.; Arbesu, M.; Kadri, I.; Luo, D.; Mizrahi, L.; Krichen, S.; Lang, M.; Tovchigrechko, A.; Lopez Carranza, N.; Sahin, U.; Beguir, K.; Rooney, M.; Fu, Y.

10.1101/2023.11.21.568057 — immunology — Posted on 2024-01-20

2063 A polymer physics view of peripheral chromatin: de Gennes' self-similar carpet

Sariyer, O. S.; Erbas, A.

10.1101/2024.01.05.574343 — biophysics — Posted on 2024-01-19

2064 Evidence that recent climatic changes have expanded the potential geographical range of the Mediterranean fruit fly

Szyniszewska, A. M.; Bieszczak, H.; Kozyra, K.; Papadopoulos, N. T.; De Meyer, M.; Nowosad, J.; Ota, N.; Kriticos, D. J.

10.1101/2023.11.15.566983 — ecology — Posted on 2024-01-19

2065 mEthAE: an Explainable AutoEncoder for methylation data

Katz, S.; Martins dos Santos, V. A. P.; Saccenti, E.; Roshchupkin, G. V.

10.1101/2023.07.18.549496 — bioinformatics — Posted on 2024-01-19

2066 L-Glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and signaling

Forbes, M.; Kempa, R.; Mastrobuoni, G.; Rayman, L.; Pietzke, M.; Bayram, S.; Arlt, B.; Spruessel, A.; Deubzer, H.; Kempa, S.

10.1101/2023.12.20.572547 — biochemistry — Posted on 2024-01-19

2067 Development and patterning of a highly versatile visual system in spiders

Baudouin Gonzalez, L.; Schoenauer, A.; Harper, A.; Arif, S.; Leite, D. J.; Steinhoff, P. O. M.; Pechmann, M.; Telizhenko, V.; Pande, A.; Kosiol, C.; McGregor, A. P.; Sumner-Rooney, L.

10.1101/2023.12.22.572789 — developmental biology — Posted on 2024-01-19

2068 The dopamine inhibitor GBR12909 improves attention and compulsive behaviour in female rats

Abdulkader, S. P.; Gigg, J.

10.1101/2023.07.07.548063 — animal behavior and cognition — Posted on 2024-01-19

2069 GGAssembler: precise and economical design and synthesis of combinatorial mutation libraries

Hoch, S. Y.; Weinstein, J. Y.; Netzer, R.; Krauss, L.; Hakeny, K.; Fleishman, S. J.

10.1101/2023.05.18.541394 — molecular biology — Posted on 2024-01-19

2070 Digital profiling of cancer transcriptomes from histology images with grouped vision attention

Zheng, Y.; Pizurica, M.; Carrillo-Perez, F.; Noor, H.; Yao, W.; Wohlfart, C.; Marchal, K.; Vladimirova, A.; Gevaert, O.

10.1101/2023.09.28.560068 — bioinformatics — Posted on 2024-01-19

2071 How to train a post-processor for tandem mass spectrometry proteomics database search while maintaining control of the false discovery rate

Freestone, J. A.; Käll, L.; Noble, W. S.; Keich, U.

10.1101/2023.10.26.564068 — bioinformatics — Posted on 2024-01-19

2072 EpiSegMix: A Flexible Distribution Hidden Markov Model with Duration Modeling for Chromatin State Discovery

Schmitz, J. E.; Aggarwal, N.; Laufer, L.; Walter, J.; Salhab, A.; Rahmann, S.

10.1101/2023.09.07.556549 — bioinformatics — Posted on 2024-01-19

2073 Ascidian embryonic cells with properties of neural-crest cells and neuromesodermal progenitors of vertebrates

Ishida, T.; Satou, Y.

10.1101/2023.05.24.542044 — developmental biology — Posted on 2024-01-19

2074 Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

Yamanaka, T.; Xiao, Z.; Tsujita, N.; Awad, M.; Umehara, T.; Shimada, M.

10.1101/2024.01.16.575926 — cell biology — Posted on 2024-01-19

2075 High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes

Locke, T. M.; Fields, R.; Gizinski, H.; Otto, G. M.; Berg, M. D.; Villen, J.; Sancak, Y.; Schweppe, D. K.

10.1101/2024.01.18.575273 — cell biology — Posted on 2024-01-19

2076 Gravitational and mechanical forces drive mitochondrial translation

10.1101/2023.01.18.524628 — molecular biology — Posted on 2024-01-19

2077 Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization

Fukumoto, J.; Yoshida, M.; Tokuoka, S. M.; Hayakawa, E. S. H.; Miyazaki, S.; Sakura, T.; Ken Inaoka, D.; Kita, K.; Usukura, J.; Shindou, H.; Tokumasu, F.

10.1101/2024.01.13.575495 — microbiology — Posted on 2024-01-19

2078 Micro-PINGUIN: Microtiter plate-based ice nucleation detection in gallium with an infra-red camera

Wieber, C.; Jeppesen, M. R.; Finster, K. W.; Melvad, C.; Santl-Temkiv, T.

10.1101/2023.09.27.559697 — microbiology — Posted on 2024-01-19

2079 Seasonal Metabolic Dynamics of Microeukaryotic Plankton: A Year-long Metatranscriptomic Study in a Temperate Sea

Perneel, M.; Lagaisse, R.; Mortelmans, J.; Maere, S.; Hablützel, P. I.

10.1101/2024.01.17.576024 — microbiology — Posted on 2024-01-19

2080 Functional connectivity, tissue microstructure and T2 at 11.1 Tesla distinguishes neuroadaptive differences in two traumatic brain injury models in rats: A Translational Outcomes Project in NeuroTrauma (TOP-NT) UG3 phase study

Kommireddy, R. S.; Mehra, S.; Pompilus, M.; Arja, R. D.; Zhu, T.; Yang, Z.; Fu, Y.; Zhu, J.; Kobeissy, F.; Wang, K. K. W.; Febo, M.

10.1101/2023.12.10.570975 — neuroscience — Posted on 2024-01-19

2081 Top-down modulation in canonical cortical circuits with short-term plasticity

Waitzmann, F.; Wu, Y. K.; Gjorgjieva, J.

10.1101/2023.06.13.544791 — neuroscience — Posted on 2024-01-19

2082 A Multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A.

Carrington, G.; Fatima, U.; Caramujo, I.; Lewis, T.; Casas-Mao, D.; Peckham, M.

10.1101/2024.01.18.576271 — cell biology — Posted on 2024-01-18

2083 Sunpheno: a deep neural network for phenological classification of sunflower images

Bengoa Luoni, S. A.; Ricci, R.; Corzo, M. A.; Hoxha, G.; Melgani, F.; Fernandez, P. d. C.

10.1101/2024.01.17.574407 — bioinformatics — Posted on 2024-01-18

2084 Muscle-controlled physics simulations of the emu (a large running bird) resolve the grounded running paradox

van Bijlert, P. A.; van Soest, A. J. K.; Schulp, A. S.; Bates, K. T.

10.1101/2024.01.17.575928 — zoology — Posted on 2024-01-18

2085 Geographic, ecological, and temporal patterns of seabird mortality during the 2022 HPAI H5N1 outbreak on the island of Newfoundland

McPhail, G. M.; Collins, S. M.; Burt, T. V.; Careen, N. G.; Doiron, P. B.; Avery-Gomm, S.; Barychka, T.; English, M.; Giacinti, J. A.; Jones, M. E. B.; Provencher, J. F.; Soos, C.; Ward, C. R. E.; Duffy, S.; Wilhelm, S. I.; Wight, J.; Rahman, I.; Hargan, K. E.; Lang, A. S.; Montevecchi, W. A.

10.1101/2024.01.17.575746 — zoology — Posted on 2024-01-18

2086 PHF6 suppresses self-renewal of leukemic stem cells in AML

Jalnapurkar, S. S.; Pawar, A.; George, S. S.; Antony, C.; Grana, J.; Gurubuxani, S.; Paralkar, V. R.

10.1101/2024.01.06.573649 — cancer biology — Posted on 2024-01-18

2087 Localising elements in single-particle reconstructions by REEL-EM: Reconstructed Electron Energy-Loss - Elemental Mapping

Pfeil-Gardiner, O.; Rosa, H. V. D.; Riedel, D.; Chen, Y. S.; Lorks, D.; Kukelhan, P.; Linck, M.; Muller, H.; Van Petegem, F.; Murphy, B. J.

10.1101/2024.01.18.575858 — biophysics — Posted on 2024-01-18

2088 Genome assembly of the edible jelly fungus Dacryopinax spathularia (Dacrymycetaceae)

Hong Kong Biodiversity Genomics Consortium, ; Hui, J. H. L.; Chan, T.-F.; Chan, L.; Cheung, S. G.; Cheang, C. C.; Fang, J.; Gaitan-Espitia, J. D.; Lau, S.; Sung, Y. H.; Wong, C.; Yip, K.; Wei, Y.; Law, S. T. S.; Chong, T. K.; Nong, W.; Yip, H. Y.

10.1101/2024.01.16.575489 — genomics — Posted on 2024-01-18

2089 Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing

Konishi, C. T.; Moulayes, N.; Butola, T.; Zhang, V.; Kagan, D.; Yang, Q.; Pressler, M.; Dirvin, B. G.; Devinsky, O.; Basu, J.; Long, C.

10.1101/2024.01.17.576134 — molecular biology — Posted on 2024-01-18

2090 Helicases DDX5 and DDX17 promote Hepatitis B Virus transcription termination heterogeneity in infected human hepatocytes

Chapus, F.; Giraud, G.; Huchon, P.; Charre, C.; Goldsmith, C.; Roda, M.; Martinez, M. G.; Fresquet, J.; Diederichs, A.; Locatelli, M.; Polveche, H.; Grand, X.; Scholtes, C.; Chemin, I.; Hernandez Vargas, H.; Rivoire, M.; Bourgeois, C.; Zoulim, F.; Testoni, B.

10.1101/2024.01.17.575990 — molecular biology — Posted on 2024-01-18

2091 Examining the influence of environmental factors on Acanthamoeba castellanii and Pseudomonas aeruginosa in co-culture

Cecil, R. E.; Yoder-Himes, D. R.

10.1101/2024.01.17.575952 — microbiology — Posted on 2024-01-18

2092 Multiple Pathways Impact Swarming Motility of Pseudomonas fluorescens Pf0-1

Pastora, A. B.; Rzasa, K.; OToole, G.

10.1101/2024.01.17.576057 — microbiology — Posted on 2024-01-18

2093 Cutting through host autofluorescence: fluorescence lifetime imaging microscopy for visualising intracellular bacteria in Symbiodiniaceae

Deore, P.; Tsang Min Ching, S. J.; Brumley, D. R.; van Oppen, M. J. H.; Hinde, E.; Blackall, L.

10.1101/2024.01.16.575970 — microbiology — Posted on 2024-01-18

2094 Decoration of Burkholderia Hcp1 protein to virus-like particles as a vaccine delivery platform.

Khakhum, N.; Baruch-Torres, N.; Stockton, J. L.; Chapartegui-Gonzalez, I. G.; Badten, A. J.; Adam, A.; Wang, T.; Huerta-Saquero, A.; Yin, W.; Torres, A. G.

10.1101/2024.01.17.576127 — microbiology — Posted on 2024-01-18

2095 Exposure of gut bacterial isolates to the anthelminthic drugs, ivermectin and moxidectin, leads to antibiotic-like phenotypes of growth inhibition and adaptation.

Dommann, J.; Keiser, J.; Garneau, J.; Gandelin, A.; Casanova, C.; Keller, P. M.; Sayasone, S.; Vonaesch, P.; Schneeberger, P.

10.1101/2024.01.17.575993 — microbiology — Posted on 2024-01-18

2096 Environmental controls of dark CO2 fixation in wetland microbiomes

Grueterich, L.; Woodhouse, J. N.; Mueller, P.; Tiemann, A.; Ruscheweyh, H. J.; Sunagawa, S.; Grossart, H. P.; Streit, W. R.

10.1101/2024.01.18.576062 — microbiology — Posted on 2024-01-18

2097 The Mechanism Insight into Bacterial Degradation of Pentachlorobiphenyl

Ji, L.; Chang, X.; Wang, L.; Fu, X.; Lai, W.; Zheng, L.; Li, Q.; Xing, Y.; Yang, Z.; Guan, Y.; Yang, F.

10.1101/2024.01.18.576235 — microbiology — Posted on 2024-01-18

2098 Gut microbiota and faecal cytokine profiles of rural Cambodian infants and links to early life nutrition and diarrhoeal episodes.

Dalby, M. J.; Kiu, R.; Serghiou, I. R.; Miyazaki, A.; Acford-Palmer, H.; Tung, R.; Caim, S.; Phillips, S.; Kujawska, M.; Matsui, M.; Iwamoto, A.; Taking, B.; Cox, S. E.; Hall, L. J.

10.1101/2023.07.24.550269 — microbiology — Posted on 2024-01-18

2099 Neisseria gonorrhoeae scavenges host sialic acid for Siglec-mediated, complement-independent suppression of neutrophil activation

Cardenas, A.; Thomas, K. S.; Broden, M. W.; Ferraro, N. J.; John, C.; Pires, M. M.; Jarvis, G. A.; Criss, A. K.

10.1101/2024.01.17.576097 — microbiology — Posted on 2024-01-18

2100 Catabolic pathway acquisition by soil pseudomonads readily enables growth with salicyl alcohol but does not affect colonization of Populus roots

Christel, S.; Carrell, A. A.; Burdick, L. H.; Villalobos Solis, M. I.; Abraham, P. E.; Jawdy, S.; Chaves, J.; Engle, N.; Berhane, T.-K.; Yao, T.; Chen, J.-G.; Muchero, W.; Tschaplinski, T.; Cregger, M. A.; Michener, J. K.

10.1101/2024.01.17.575957 — microbiology — Posted on 2024-01-18

2101 Evaluating Evapotranspiration in a Commercial Greenhouse: A Comparative Study of Microclimatic Factors and Machine-Learning Algorithms

Averbuch, N.; Moshelion, M.

10.1101/2024.01.11.575151 — plant biology — Posted on 2024-01-18

2102 EvoAug-TF: Extending evolution-inspired data augmentations for genomic deep learning to TensorFlow

Koo, P.; Yu, Y.; Muthukumar, S.

10.1101/2024.01.17.575961 — bioinformatics — Posted on 2024-01-18

2103 Insights from comparative plastid genomics of colorless facultative pathogens Prototheca (Chlorophyta): Unveiling membrane transport and organelle division as key functions

Maciszewski, K.; Wilga, G.; Jagielski, T.; Bakula, Z.; Gawor, J.; Gromadka, R.; Karnkowska, A.

10.1101/2024.01.16.575923 — evolutionary biology — Posted on 2024-01-18

2104 Neutralizing gut-derived lipopolysaccharide as a novel therapeutic strategy for severe leptospirosis

Xie, X.; Chen, X.; Zhang, S.; Liu, J.; Zhang, W.; Cao, Y.

10.1101/2024.01.17.576119 — microbiology — Posted on 2024-01-18

2105 Complementary cognitive roles for D2-MSNs and D1-MSNs in interval timing

Bruce, R.; Weber, M. A.; Bova, A.; Volkman, R.; Jacobs, C.; Sivakumar, K.; Kim, Y.; Curtu, R.; Narayanan, N.

10.1101/2023.07.25.550569 — neuroscience — Posted on 2024-01-18

2106 The glucocorticoid response element near the sphingosine-1-phopshate receptor 3 gene mitigates inflammatory processes and maladaptive behavior in females and stressed males

Corbett, B. F.; Luz, S.; Arner, J.; Castro-Vildsola, J.; Yan, J.; Bhatnagar, S.

10.1101/2024.01.09.574910 — neuroscience — Posted on 2024-01-18

2107 Early evolution of the ecdysozoan body plan

Wang, D.; Qiang, Y.; Guo, J.; Vannier, J.; Song, Z.; Peng, J.; Zhang, B.; Sun, J.; Yu, Y.; Zhang, Y.; Zhang, T.; Yang, X.; Han, J.

10.1101/2024.01.16.575973 — paleontology — Posted on 2024-01-18

2108 Characterization of a novel humanized heavy chain antibody targeting endogenous retroviruses with anti-lymphoma activity

Spriano, F.; Cascione, L.; Sgrignani, J.; Bendik, N.; Napoli, S.; Sartori, G.; Cannas, E.; Gong, T.; Arribas, A. J.; Pizzi, M.; Rossi, D.; Robbiani, D. F.; Cavalli, A.; Bertoni, F.

10.1101/2024.01.17.576027 — cancer biology — Posted on 2024-01-18

2109 ZygosityPredictor

Rheinnecker, M.; Froehlich, M.; Ruebsam, M.; Paramasivam, N.; Heilig, C. E.; Froehling, S.; Schlenk, R. F.; Hutter, B.; Huebschmann, D.

10.1101/2023.03.09.531877 — bioinformatics — Posted on 2024-01-18

2110 Glycan-costumed virus-like particles promote type 1 anti-tumor immunity

Lensch, V.; Gabba, A.; Hincapie, R.; Bhagchandani, S. H.; Basak, A.; Alam, M. M.; Irvine, D. J.; Shalek, A. K.; Johnson, J. A.; Finn, M. G.; Kiessling, L. L.

10.1101/2024.01.18.575711 — biochemistry — Posted on 2024-01-18

2111 Leveraging co-evolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms

Snoeck, S.; Lee, H. K.; Schmid, M. W.; Bender, K. W.; Neeracher, M. J.; Fernandez-Fernandez, A. D.; Santiago, J.; Zipfel, C.

10.1101/2024.01.18.575556 — biochemistry — Posted on 2024-01-18

2112 Chromosomal-level genome assembly of the long-spined sea urchin Diadema setosum (Leske, 1778)

10.1101/2024.01.16.575490 — genomics — Posted on 2024-01-18

2113 Chronic disturbance of moist tropical forests favours deciduous over evergreen tree communities across a climate gradient in the Western Ghats

Biswas, N.; Sadekar, V.; Biniwale, S.; Taneja, Y.; Osuri, A.; Page, N.; Suryawanshi, K.; Naniwadekar, R.

10.1101/2024.01.16.575954 — ecology — Posted on 2024-01-18

2114 Ecological lifestyle and gill slit height across sharks

VanderWright, W. J.; Bigman, J. S.; Iliou, A. S.; Dulvy, N. K.

10.1101/2024.01.17.574433 — ecology — Posted on 2024-01-18

2115 Revealing the drivers of antibiotic resistance trends in Streptococcus pneumoniae amidst the 2020 COVID-19 pandemic: Insights from mathematical modeling

Kovacevic, A.; Smith, D. R. M.; Rahbe, E.; Novelli, S.; Henriot, P.; Varon, E.; Cohen, R.; Levy, C.; Temime, L.; Opatowski, L.

10.1101/2022.08.08.503267 — ecology — Posted on 2024-01-18

2116 The embryonic role of juvenile hormone in the firebrat, Thermobia domestica, reveals its function before its involvement in metamorphosis

Truman, J. W.; M. Riddiford, L.; Konopova, B.; Nouzova, M.; Noriega, F.; Herko, M.

10.1101/2023.10.06.561279 — developmental biology — Posted on 2024-01-18

2117 High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes

Locke, T. M.; Fields, R.; Gizinski, H.; Otto, G. M.; Berg, M. D.; Villen, J.; Sancak, Y.; Schweppe, D. K.

10.1101/2024.01.18.575273 — cell biology — Posted on 2024-01-18

2118 Bridging Viruses and Prokaryotic Host through Miniature Inverted-repeat Transposable Elements (MITEs)

Nadal-Molero, F.; Rosselli, R.; Garcia-Juan, S.; Campos-Lopez, A.; Martin-Cuadrado, A. B.

10.1101/2024.01.18.576219 — microbiology — Posted on 2024-01-18

2119 Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex

Meissner-Bernard, C.; Zenke, F.; Friedrich, R. W.

10.1101/2023.12.12.571272 — neuroscience — Posted on 2024-01-18

2120 Disruption of consciousness depends on insight in OCD and on positive symptoms in schizophrenia

Tumkaya, S.; Yucens, B.; Gunduz, M.; Maheu, M.; Berkovitch, L.

10.1101/2024.01.02.571832 — neuroscience — Posted on 2024-01-18

2121 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles

Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.

10.1101/2023.07.04.547323 — neuroscience — Posted on 2024-01-18

2122 ACID: A Comprehensive Toolbox for Image Processing and Modeling of Brain, Spinal Cord, and Post-mortem Diffusion MRI Data

David, G.; Fricke, B.; Oeschger, J. M.; Ruthotto, L.; Fritz, F. J.; Ohana, O.; Sauvigny, T.; Freund, P.; Tabelow, K.; Mohammadi, S.

10.1101/2023.10.13.562027 — neuroscience — Posted on 2024-01-18

2123 Grouping cells in primate visual cortex

Franken, T. P.; Reynolds, J. H.

10.1101/2024.01.16.575953 — neuroscience — Posted on 2024-01-18

2124 Knowledge Innovation Ecosystem for the Promotion of User-Centre Health Innovations: Living Lab Methodology and Lessons Learned Through the Proposal of Standard Good Practices

Rosa, N.; Leite, S.; Alves, J.; Carvalho, A.; Oliveira, D.; Santos, F.; Macedo, B.; Prazeres, H.

10.1101/2024.01.17.573578 — scientific communication and education — Posted on 2024-01-18

2125 Phase 1 of the NIH Preprint Pilot: Testing the viability of making preprints discoverable in PubMed Central and PubMed

Funk, K.; Zayas-Caban, T.; Beck, J.

10.1101/2022.12.12.520156 — scientific communication and education — Posted on 2024-01-18

2126 RORc expressing immune cells negatively regulate tertiary lymphoid structure formation and support their pro-tumorigenic functions

Cinnamon, E.; Stein, I.; Zino, E.; Rabinovich, S.; Shovman, Y.; Schlesinger, Y.; Salame, T. M.; Reich-Zeliger, S.; Lotem, M.; Ben-Neriah, Y.; Parnas, O.; Pikarsky, E.

10.1101/2022.07.02.498540 — cancer biology — Posted on 2024-01-18

2127 The pharmacogenomic assessment of molecular epithelial-mesenchymal transition signatures reveals drug susceptibilities in cancer cell lines

Ohnmacht, A. J.; Avar, G.; Schübel, M. K.; O'Neill, T. J.; Krappmann, D.; Menden, M. P.

10.1101/2024.01.16.575190 — cancer biology — Posted on 2024-01-18

2128 GotGlycans: Role of N343 Glycosylation on the SARS-CoV-2 S RBD Structure and Co-Receptor Binding Across Variants of Concern

Ives, C. M.; Nguyen, L.; Fogarty, C. A.; Harbison, A. M.; Durocher, Y.; Klassen, J. S.; fadda, e.

10.1101/2023.12.05.570076 — biophysics — Posted on 2024-01-18

2129 Contextualizing protein representations using deep learning on protein networks and single-cell data

Li, M. M.; Huang, Y.; Sumathipala, M.; Liang, M. Q.; Valdeolivas, A.; Ananthakrishnan, A. N.; Liao, K.; Marbach, D.; Zitnik, M.

10.1101/2023.07.18.549602 — bioinformatics — Posted on 2024-01-18

2130 A Distributed Computing Solution for Privacy-Preserving Genome-Wide Association Studies

Brito, C.; Ferreira, P. G.; Paulo, J.

10.1101/2024.01.15.575678 — bioinformatics — Posted on 2024-01-18

2131 SLEDGe: Inference of ancient whole genome duplications using machine learning

Sutherland, B. L.; Tiley, G. P.; McKibben, M.; Barker, M. S.

10.1101/2024.01.17.574559 — bioinformatics — Posted on 2024-01-18

2132 In vitro cultivation techniques for modeling liver organogenesis, building assembloids, and designing synthetic tissues

Kumar, S.; Patel, H.; Parshurama, N.

10.1101/2023.09.30.560154 — bioengineering — Posted on 2024-01-18

2133 Mobile-CRISPRi as a powerful tool for modulating Vibrio gene expression

Geyman, L. J.; Tanner, M.; Rosario-Melendez, N.; Peters, J.; Mandel, M. J.; van Kessel, J. C.

10.1101/2024.01.17.575898 — molecular biology — Posted on 2024-01-18

2134 TopBP1 utilises a bipartite GINS binding mode to support genome replication

Day, M.; Tetik, B.; Parlak, M.; Almeida-Hernandez, Y.; Raeschle, M.; Kaschani, F.; Siegert, H.; Marko, A.; Sanchez-Garcia, E.; Kaiser, M.; Barker, I.; Pearl, L. H.; Oliver, A.; Boos, D.

10.1101/2023.03.31.535063 — molecular biology — Posted on 2024-01-18

2135 In vivo delivery of functional Cas:DNA nucleoprotein complexes into recipient bacteria through a Type IV Secretion System

Guzman-Herrador, D. L.; Fernandez-Gomez, A.; Depardieu, F.; Bikard, D.; Llosa, M.

10.1101/2024.01.18.576218 — microbiology — Posted on 2024-01-18

2136 Targeted metagenomics using probe capture detect a larger diversity of nitrogen and methane cyclinggenes in complex microbial communities than traditional metagenomics

Siljanen, H. M. P.; Manoharan, L.; Hilts, A. S.; Bagnoud, A.; Alves, R. J. E.; Jones, C. M.; Kerou, M.; Sousa, F.; Hallin, S.; Biasi, C.; Schleper, C.

10.1101/2022.11.04.515048 — microbiology — Posted on 2024-01-18

2137 Low humidity enhances Zika virus infection and dissemination in Aedes aegypti mosquitoes

Abu, A. E. I.; Becker, M.; Accoti, A.; Sylla, M.; Dickson, L.

10.1101/2024.01.17.576075 — microbiology — Posted on 2024-01-18

2138 Contrasting Phyllosphere Mycobiome in two Lycopodiaceae Plant Species: Unraveling Potential HupA-Producing Fungi and Fungal Interactions

Lin, L.; Li, C.; Chang, C.-C.; Du, R.; Ji, J.; Kuo, L.-Y.; Wang, L.; Chen, K.-H.

10.1101/2024.01.18.576228 — microbiology — Posted on 2024-01-18

2139 Identification of a viral gene essential for the genome replication of a domesticated endogenous virus in ichneumonid parasitoid wasps

Lorenzi, A.; Legeai, F.; Jouan, V.; Girard, P.-A.; Strand, M.; Ravallec, M.; Eychenne, M.; Bretaudeau, A.; Robin, S.; Rochefort, J.; Villegas, M.; Burke, G.; Rebollo, R.; Negre, N.; Volkoff, A.-N.

10.1101/2024.01.18.576166 — microbiology — Posted on 2024-01-18

2140 C-di-AMP accumulation disrupts glutathione metabolism and inhibits virulence program expression in Listeria monocytogenes

Siletti, C.; Freeman, M. J.; Tu, Z.; Stevenson, D. M.; Amador-Noguez, D.; Sauer, J.-D.; Huynh, T. N.

10.1101/2024.01.18.576247 — microbiology — Posted on 2024-01-18

2141 Eukaryotic genomic data uncover an extensive host range of mirusviruses

Zhao, H.; Meng, L.; Hikida, H.; Ogata, H.

10.1101/2024.01.18.576163 — microbiology — Posted on 2024-01-18

2142 N -acetylglucosamine supplementation fails to bypass the critical acetylation of glucosamine-6-phosphate required for Toxoplasma gondii replication and invasion

Alberione, M. P.; Gonzalez-Ruiz, V.; Rudaz, S.; Soldati-Favre, D.; Izquierdo, L.; Kloehn, J.

10.1101/2024.01.18.576165 — microbiology — Posted on 2024-01-18

2143 Characterisation of anhydro-sialic acid transporters from mucosa-associated bacteria

Wu, Y.; Bell, A.; Thomas, G. H.; Bolam, D. N.; Sargent, F.; Juge, N.; Palmer, T.; SEVERI, E.

10.1101/2024.01.17.576040 — microbiology — Posted on 2024-01-18

2144 Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity

Agharkar, A. N.; Hajra, D.; Roy, D.; Jaiswal, V.; Kabi, P.; Chakravortty, D.; Basu, S.

10.1101/2024.01.17.576159 — microbiology — Posted on 2024-01-18

2145 Persistence and Free Chlorine Disinfection of Human Coronaviruses and Their Surrogates in Water

Zhang, M.; Leong, M.; Mitch, W.; Blish, C. A.; Boehm, A. B.

10.1101/2024.01.16.575911 — microbiology — Posted on 2024-01-18

2146 Seasonal Metabolic Dynamics of Microeukaryotic Plankton: A Year-long Metatranscriptomic Study in a Temperate Sea

Perneel, M.; Lagaisse, R.; Mortelmans, J.; Maere, S.; Habluzel, P. I.

10.1101/2024.01.17.576024 — microbiology — Posted on 2024-01-18

2147 A Bacteriophage Cocktail Targeting Yersinia pestis Provides Strong Post-Exposure Protection in a Rat Pneumonic Plague Model

Kilgore, P. B.; Sha, J.; Hendrix, E.; Neil, B. H.; Lawrence, W. S.; Peel, J.; Hittle, L.; Woolston, J.; Sulakvelidze, A.; Schwartz, J.; Chopra, A. K.

10.1101/2024.01.17.576055 — microbiology — Posted on 2024-01-18

2148 Fluoride export is required for competitive fitness of pathogenic microorganisms in dental biofilm models

Banerjee, A.; Kang, C.-Y.; An, M.; Koff, B. B.; Sunder, S.; Kumar, A.; Tenuta, L. M. A.; Stockbridge, R. B.

10.1101/2024.01.18.576223 — microbiology — Posted on 2024-01-18

2149 Architecture of genome-wide transcriptional regulatory network reveals dynamic functions and evolutionary trajectories in Pseudomonas syringae

Sun, Y.; Li, J.; Huang, J.; Li, S.; Li, Y.; Deng, X.

10.1101/2024.01.18.576191 — microbiology — Posted on 2024-01-18

2150 The Bacillus subtilis cell envelope stress-inducible ytpAB operon modulates membrane properties and contributes to bacitracin resistance

Willdigg, J. R.; Patel, Y.; Arquilevich, B. E.; Subramanian, C.; Frank, M. W.; Rock, C. O.; Helmann, J. D.

10.1101/2024.01.17.576085 — microbiology — Posted on 2024-01-18

2151 Co-occurrence Networks and Topological Analyses Revealed Microbiome Structures in Soybean Roots from a Louisiana Soybean Field Severely Damaged by Prolonged High Temperatures and Drought Stress

Gouli, S.; Majeed, A.; Liu, J.; Moseley, D.; Mukhtar, M. S.; Ham, J. H.

10.1101/2024.01.16.575963 — microbiology — Posted on 2024-01-18

2152 Emerging Mycobacterium bovis in Lebanon: a snapshot based on whole-genome sequencing.

Jouaid, I.; Sobh, G.; Araj, G. F.; Achache, W.; Grine, G.; Tokajian, S.; Al Khoury, C.; Abdel-Sater, F.; Drancourt, M.; Saad, J.

10.1101/2024.01.18.576209 — microbiology — Posted on 2024-01-18

2153 Multiomics analysis reveals B. MO1 as a distinct Babesia species and provides insights into its evolution and virulence.

Singh, P.; Vydyam, P.; Fang, T.; Kumar, M.; Estrada, K.; Grande, R.; Sanchez-Flores, A.; Gonzalez, L. M.; Montero, E.; Chakravarty, S.; Lonardi, S.; Berry, V.; Ranwez, V.; Carcy, B.; Depoix, D.; Sanchez, S.; Cornillot, E.; Abel, S.; Ciampossin, L.; Lenz, T.; Le Roch, K. G.; Harb, O. S.; Ben Mamoun, C.

10.1101/2024.01.17.575932 — microbiology — Posted on 2024-01-18

2154 Comparative analysis of retroviral Gag-host cell interactions: focus on the nuclear interactome

Lambert, G. S.; Rice, B. L.; Kaddis Maldonado, R. J.; Chang, J.; Parent, L. J.

10.1101/2024.01.18.575255 — microbiology — Posted on 2024-01-18

2155 Colistin resistance genes in Escherichia coli isolated from patients with urinary tract infections

Almomani, W. M.; Ata, N.; Maslat, A.

10.1101/2024.01.16.575981 — microbiology — Posted on 2024-01-18

2156 Birth weight and in-feed antibiotics alter the assembly and succession of the swine gut microbiota

Dong, W.; Oladele, P. O.; Centeno-Martinez, E.; Sheets, T. R.; Richert, B. T.; Johnson, T. A.

10.1101/2024.01.17.576096 — microbiology — Posted on 2024-01-18

2157 Exploratory mass cytometry analysis reveals immunophenotypes of cancer treatment-related pneumonitis

Yanagihara, T.; Hata, K.; Matsubara, K.; Kunimura, K.; Suzuki, K.; Tsubouchi, K.; Ikegame, S.; Baba, Y.; Fukui, Y.; Okamoto, I.

10.1101/2023.02.21.529383 — immunology — Posted on 2024-01-18

2158 The human pupil and face encode sound affect and provide objective signatures of tinnitus and auditory hypersensitivity disorders

Smith, S. S.; Jahn, K. N.; Sugai, J. A.; Hancock, K. E.; Polley, D. B.

10.1101/2023.12.22.571929 — neuroscience — Posted on 2024-01-18

2159 Local translation is engaged to sustain circuit integrity in severed preserved axonal and synaptic projections

Paglione, M.; Restivo, L.; Zakhia, S.; Llobet Rosell, A.; Terenzio, M.; Neukomm, L. J.

10.1101/2023.08.18.553870 — neuroscience — Posted on 2024-01-18

2160 A neurocomputational account of the link between social perception and social action

Bas, L. M.; Roberts, I. D.; Hutcherson, C.; Tusche, A.

10.1101/2023.10.02.560256 — neuroscience — Posted on 2024-01-18

2161 Representational similarity learning reveals a graded multi-dimensional semantic space in the human anterior temporal cortex

Cox, C. R.; Rogers, T. T.; Shimotake, A.; Kikuchi, T.; Kunieda, T.; Miyamoto, S.; Takahashi, R.; Matsumoto, R.; Ikeda, A.; Ralph, M. A. L.

10.1101/2022.10.27.514039 — neuroscience — Posted on 2024-01-18

2162 Deciphering the Molecular Mechanism of Post-Acute Sequelae of COVID-19 through Comorbidity Network Analysis

Tian, L.; Zhang, Q.

10.1101/2024.01.17.575851 — pathology — Posted on 2024-01-18

2163 Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids

Haloi, N.; Huang, S.; Nichols, A. L.; Fine, E. J.; Friesenhahn, N. J.; Marotta, C. B.; Dougherty, D. A.; Lindahl, E.; Howard, R. J.; Mayo, S. L.; Lester, H. A.

10.1101/2023.01.16.524298 — bioengineering — Posted on 2024-01-18

2164 The non-muscle actinopathy-associated mutation E334Q in cytoskeletal gamma-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins

Greve, J. N.; Marquardt, A.; Heiringhoff, R.; Reindl, T.; Thiel, C.; Di Dinato, N.; Taft, M. H.; Manstein, D. J.

10.1101/2023.09.10.557040 — biochemistry — Posted on 2024-01-18

2165 Kinases in motion: impact of protein and small molecule interactions on kinase conformations

Kugler, V.; Schwaighofer, S.; Feichtner, A.; Enzler, F.; Fleischmann, J.; Strich, S.; Schwarz, S.; Wilson, R.; Tschaikner, P.; Troppmair, J.; Sexl, V.; Meier, P.; Kaserer, T.; Stefan, E.

10.1101/2024.01.11.575270 — biochemistry — Posted on 2024-01-18

2166 SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes

GRANADOS, A.; ZAMPERONI, M.; RAPONE, R.; MOULIN, M.; BOYARCHUK, E.; BOUYIOUKOS, C.; DEL MAESTRO, L.; JOLIOT, V.; NEGRONI, E.; MOHAMED, M.; PIQUET, S.; BIGOT, A.; LE GRAND, F.; ALBINI, S.; AIT-SI-ALI, S.

10.1101/2023.06.28.546840 — cell biology — Posted on 2024-01-18

2167 Hypoxia evokes a sequence of raphe-pontomedullary network operations for inspiratory drive amplification and gasping

Nuding, S. C.; Segers, L. S.; Iceman, K.; O'Connor, R.; Dean, J. B.; Valarezo, P. A.; Shuman, D.; Solomon, I. C.; Bolser, D. C.; Morris, K. F.; Lindsey, B. G.

10.1101/2023.11.07.566027 — neuroscience — Posted on 2024-01-18

2168 scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome

Faehnrich, A.; Reddy, K.; Ott, F.; Maluje, Y.; Saurabh, R.; Schaaf, A.-C.; Winkelmann, S.; Voss, B.; Laudien, M.; Bahmer, T.; Heyckendorf, J.; Brinkmann, F.; Schreiber, S.; Lieb, W.; Weckmann, M.; Busch, H.

10.1101/2024.01.10.574801 — genomics — Posted on 2024-01-18

2169 ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway

Veronese, M.; Kallabis, S.; Kaczmarek, A.; Robers, L.; Schumacher, S.; Das, A.; Lofrano, A.; Brodesser, S.; Müller, S.; Hofmann, K.; Krüger, M.; Rugarli, E. I.

10.1101/2024.01.17.576039 — cell biology — Posted on 2024-01-18

2170 Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling

Dogra, D.; Phan, V. A.; Gavrilovici, C.; DiMarzo, N.; Ibhazehiebo, K.; Kurrasch, D. M.

10.1101/2024.01.15.575806 — neuroscience — Posted on 2024-01-18

2171 Molecular dynamics simulation analysis of structural dynamic cross correlation induced by odorant hydrogen-bonding in mouse eugenol olfactory receptor

Okamoto, C.; Ando, K.

10.1101/2023.11.05.565671 — biophysics — Posted on 2024-01-18

2172 Biodiversity shows unique responses to land-use change across regional biomes

Bevan, P. A.; Ferreira, G. B.; Ingram, D. J.; Rowcliffe, M.; Young, L.; Freeman, R.; Jones, K. E.

10.1101/2023.03.08.531730 — ecology — Posted on 2024-01-18

2173 Erroneous compensation for long-latency feedback delays as origin of Essential Tremor

Blondiaux, F.; Colmant, L.; Lebrun, L.; Hanseeuw, B.; Crevecoeur, F.

10.1101/2024.01.11.575204 — neuroscience — Posted on 2024-01-18

2174 Expansion Strategy-Driven Micron-Level Resolution Mass Spectrometry Imaging of Lipids in Mouse Brain Tissue

Hung, Y. L.; Xie, C.; Wang, J.; Diao, X.; Li, R.; Wang, X.; Qiu, S.; Fang, J.; Cai, Z.

10.1101/2023.08.28.555097 — biochemistry — Posted on 2024-01-18

2175 High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding

Michell, C.; Collins, J.; Laine, P. K.; Fekete, Z.; Tapanainen, R.; Wood, J. M. D.; Goffart, S.; Pohjoismaki, J. L. O.

10.1101/2023.08.29.555262 — genomics — Posted on 2024-01-18

2176 Parallel genetic excisions of the cardiac troponin I N-terminal extension in tachycardic mammals

Joyce, W.; He, K.; Zhang, M.; Ogunsola, S.; Wu, X.; Joseph, K. T.; Bogomolny, D.; Yu, W.; Springer, M. S.; Xie, J.; Signore, A.; Campbell, K. L.

10.1101/2023.05.19.541292 — evolutionary biology — Posted on 2024-01-18

2177 SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes

10.1101/2023.06.28.546840 — cell biology — Posted on 2024-01-18

2178 Discovery of hypercompact epigenetic modulators for persistent CRISPR-mediated gene activation

Carosso, G. A.; Yeo, R. W.; Gainous, T. B.; Jawaid, Z.; Yang, X.; Kim, J. Y. S.; Jadhav, K.; Sing, N.; Boregowda, S. V.; Cutillas, V.; Qi, L. S.; Collin de l'Hortet, A.; Daley, T. P.; Hart, D. O.

10.1101/2023.06.02.543492 — synthetic biology — Posted on 2024-01-18

2179 IOBR2: Multidimensional Decoding Tumor Microenvironment for Immuno-Oncology Research

Zeng, D.; Fang, Y.; Luo, P.; Qiu, W.; Wang, S.; Shen, R.; Gu, W.; Huang, X.; Mao, Q.; Lai, Y.; Xu, X.; Shi, M.; Yu, G.; Liao, W.

10.1101/2024.01.13.575484 — cancer biology — Posted on 2024-01-17

2180 Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism

Nshanian, M.; Geller, B. S.; Gruber, J. J.; Chleilat, F.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.

10.1101/2024.01.11.575111 — genetics — Posted on 2024-01-17

2181 Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses

Currie, J.; Manda, V.; Robinson, S. K.; Lai, C.; Agnihotri, V.; Hidalgo, V.; Ludwig, R. W.; Zhang, K.; Wang, Z. V.; Rhee, J.-W.; Lam, M. P. Y.; Lau, E.

10.1101/2023.01.04.521821 — cell biology — Posted on 2024-01-17

2182 Conditional Chemoconnectomics (cCCTomics): Conditional Targeting of Chemical Transmission Efficiently

Mao, R.; Yu, J.; Deng, B.; Dai, X.; Du, Y.; Du, S.; Zhang, W.; Rao, Y.

10.1101/2023.09.26.559642 — neuroscience — Posted on 2024-01-17

2183 A feature-specific prediction error model explains dopaminergic heterogeneity

Lee, R. S.; Sagiv, Y.; Engelhard, B.; Witten, I. B.; Daw, N. D.

10.1101/2022.02.28.482379 — neuroscience — Posted on 2024-01-17

2184 Incremental Accumulation of Linguistic Context in Artificial and Biological Neural Networks

Tikochinski, R.; Goldstein, A.; Meiri, Y.; Hasson, U.; Reichart, R.

10.1101/2024.01.15.575798 — neuroscience — Posted on 2024-01-17

2185 Cross-subject Mapping of Neural Activity with Restricted Boltzmann Machines

Yang, H.; Angjelichinoski, M.; Wu, S.; Putney, J.; Sponberg, S.; Tarokh, V.

10.1101/2023.04.14.536854 — neuroscience — Posted on 2024-01-17

2186 Machine-Learning Identifies a Strategy for Differentiation Therapy in Solid Tumors

Sinha, S.; Alcantara, J.; Perry, K.; Castillo, V.; Espinoza, C. R.; Taheri, S.; Vidales, E.; Tindle, C.; Adel, A.; Amirfakhri, S.; Sawires, J. R.; Yang, J.; Bouvet, M.; Sahoo, D.; Ghosh, P.

10.1101/2023.09.13.557628 — cancer biology — Posted on 2024-01-17

2187 Eliminating the missing cone challenge through innovative approaches

Gillman, C.; Bu, G.; Danelius, E.; Hattne, J.; Nannenga, B.; Gonen, T.

10.1101/2024.01.11.575283 — biochemistry — Posted on 2024-01-17

2188 Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

Yamanaka, T.; Xiao, Z.; Tsujita, N.; Awad, M.; Umehara, T.; Shimada, M.

10.1101/2024.01.16.575926 — cell biology — Posted on 2024-01-17

2189 Oxygen intrusions sustain aerobic nitrite-oxidizing bacteria in anoxic marine zones

Buchanan, P. J.; Sun, X.; Weissman, J. L.; McCoy, D.; Bianchi, D.; Zakem, E.

10.1101/2023.02.22.529547 — systems biology — Posted on 2024-01-17

2190 Unraveling principles of thermodynamics for genome-scale metabolic networks using graph neural networks

Fan, W.; Ding, C.; Huang, D.; Zheng, W.; Dai, Z.

10.1101/2024.01.15.575679 — systems biology — Posted on 2024-01-17

2191 Proteome-scale tagging and functional screening in mammalian cells by ORFtag

Nemcko, F.; Himmelsbach, M.; Loubiere, V.; Yelagandula, R.; Pagani, M.; Brennecke, J.; Elling, U.; Stark, A.; Ameres, S. L.

10.1101/2024.01.16.575827 — systems biology — Posted on 2024-01-17

2192 Exploring human rare disease variants from a multidimensional perspective illuminates receptor - G protein coupling diversity

Redfern-Nichols, T. B.; O'Brien, S. L.; Huang, X.; Medel-Lacruz, B.; Calebiro, D.; Selent, J.; Ladds, G.; Marti Solano, M.

10.1101/2024.01.16.575841 — systems biology — Posted on 2024-01-17

2193 SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

Zhang, L.; Hsu, J. I.; Braekeleer, E. D.; Chen, C.-w.; Patel, T. D.; Martell, A. G.; Guzman, A. G.; Wohlan, K.; Waldvogel, S. M.; Urya, H.; Tovy, A.; Callen, E.; Murdaugh, R. L.; Richard, R. U.; Jansen, S.; Vissers, L.; de Vries, B. B.; Nussenzweig, A.; Huang, S.; Coarfa, C.; Anastas, J. N.; Takahashi, K.; Vassiliou, G. S.; Goodell, M. A.

10.1101/2023.08.31.555634 — cancer biology — Posted on 2024-01-17

2194 Deciphering the diversity and sequence of extracellular matrix and cellular spatial patterns in lung adenocarcinoma using topological data analysis

Yoon, I. H. R.; Jenkins, R.; Colliver, E.; Zhang, H.; Novo, D.; Moore, D.; Ramsden, Z.; Rullan, A.; Fu, X.; Yuan, Y.; Harrington, H. A.; Swanton, C.; Byrne, H. M.; Sahai, E.

10.1101/2024.01.05.574362 — cancer biology — Posted on 2024-01-17

2195 Utilizing a dual endogenous reporter system to identify functional regulators of aberrant stem cell and differentiation activity in colorectal cancer

Spisak, S.; Chen, D.; Likasitwatanakul, P.; Doan, P.; Li, Z.; Bala, P.; Vizkeleti, L.; De Silva, P.; Giannakis, M.; Wolpin, B.; Qi, J.; Sethi, N.

10.1101/2023.06.21.545895 — cancer biology — Posted on 2024-01-17

2196 DNA damage-induced PARP/ALC1 activation leads to Epithelial-to-Mesenchymal transition stimulating homologous recombination.

Rajabi, F.; Smith, R.; Liu-Bordes, W.-Y.; Schertzer, M.; Huet, S.; Londono-Vallejo, J.-A.

10.1101/2024.01.16.575847 — cancer biology — Posted on 2024-01-17

2197 Oncogenic KRASG12D extrinsically induces an immunosuppressive microenvironment in lung adenocarcinoma

Lasse-Opsahl, E.; Baliira, R.; Barravecchia, I.; McLintock, E.; Lee, J. M.; Ferris, S. F.; Espinoza, C. E.; Hinshaw, R.; Cavanaugh, S.; Robotti, M.; Brown, K.; Donahue, K.; Abdelmalak, K. Y.; Galban, C. J.; Frankel, T. L.; Zhang, Y.; Pasca di Magliano, M.; Galban, S.

10.1101/2024.01.16.568090 — cancer biology — Posted on 2024-01-17

2198 VPAC2 receptor signaling promotes pancreatic cancer cell growth and decreases the immunogenicity of the tumor microenvironment.

Passang, T.; Wang, S.; Zhang, H.; Zeng, F.; Hsu, P.-C.; Wang, W.; Li, J. M.; Liu, Y.; Ravindranathan, S.; Lesinski, G. B.; Waller, E. K.

10.1101/2024.01.16.575872 — cancer biology — Posted on 2024-01-17

2199 Unveiling common transcriptomic features between melanoma brain metastases and neurodegenerative diseases

Soler-Saez, I.; Karz, A.; Hidalgo, M. R.; Gomez-Cabanes, B.; Lopez-Cerdan, A.; Catala-Senent, J. F.; de la Iglesia-Vaya, M.; Hernando, E.; Garcia-Garcia, F.

10.1101/2024.01.16.575868 — cancer biology — Posted on 2024-01-17

2200 Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes

Pyle, E.; Zanetti, G.

10.1101/2024.01.17.576008 — biophysics — Posted on 2024-01-17

2201 Predicting how lipid composition controls protein curvature sensing with a continuum bilayer membrane model

Fu, Y.; Johnson, D.; Beaven, A.; Sodt, A. J.; Zeno, W. F.; Johnson, M. E.

10.1101/2024.01.15.575755 — biophysics — Posted on 2024-01-17

2202 Single-Molecule Force Spectroscopy of Toehold-Mediated Strand Displacement

Walbrun, A.; Wang, T.; Matthies, M.; Sulc, P.; Simmel, F. C.; Rief, M.

10.1101/2024.01.16.575816 — biophysics — Posted on 2024-01-17

2203 CryoRhodopsins: a comprehensive characterization of a new clade of microbial rhodopsins from cold environments

Lamm, G. H. U.; Marin, E.; Schellbach, A. V.; Stetsenko, A.; Alekseev, A.; Bourenkov, G.; Borshchevskiy, V.; Asido, M.; Agthe, M.; Engilberge, S.; Rose, S. L.; Caramello, N.; Royant, A.; Schneider, T. R.; Bateman, A. I.; Mager, T.; Moser, T.; Wachtveitl, J.; Guskov, A.; Kovalev, K.

10.1101/2024.01.15.575777 — biophysics — Posted on 2024-01-17

2204 Protein Translation Can Fluidize Bacterial Cytoplasm

Bera, P.; Abdul, W.; Bakshi, S.; Mondal, J.

10.1101/2024.01.16.575857 — biophysics — Posted on 2024-01-17

2205 DARDN: A deep-learning approach for CTCF binding sequence classification and oncogenic regulatory feature discovery

Cho, H. J.; Wang, Z.; Cong, Y.; Bekiranov, S.; Zhang, A.; Zang, C.

10.1101/2023.11.17.567502 — bioinformatics — Posted on 2024-01-17

2206 Restraint Validation of Biomolecular Structures Determined by NMR in the Protein Data Bank

10.1101/2024.01.15.575520 — bioinformatics — Posted on 2024-01-17

2207 MassDash: A Web-based Dashboard for Targeted Mass Spectrometry Visualization

Sing, J. C.; Charkow, J.; AlHigaylan, M.; Horecka, I.; Xu, L.; Roest, H. L.

10.1101/2024.01.15.575772 — bioinformatics — Posted on 2024-01-17

2208 MCLand: A Python program for drawing emerging shapes of Waddington's epigenetic landscape by Monte Carlo simulations

Chong, K. H.; Zhang, X.; Zhu, L.; Zheng, J.

10.1101/2024.01.15.575795 — bioinformatics — Posted on 2024-01-17

2209 BSAlign: a library for nucleotide sequence alignment

Shao, H.; Ruan, J.

10.1101/2024.01.15.575791 — bioinformatics — Posted on 2024-01-17

2210 ImmCellTyper: an integrated computational pipeline for systematic mining of Mass Cytometry data to assist deep immune profiling

Sun, J.; Choy, D.; Sompairac, N.; Jamshidi, S.; Mishto, M.; Kordasti, S.

10.1101/2024.01.15.575790 — bioinformatics — Posted on 2024-01-17

2211 Digital Microbe: A Genome-Informed Data Integration Framework for Collaborative Research on Emerging Model Organisms

Veseli, I.; Cooper, Z. S.; DeMers, M. A.; Schechter, M. S.; Miller, S.; Weber, L.; Smith, C. B.; Rodriguez, L. T.; Schroer, W. F.; McIlvin, M. R.; Lopez, P. Z.; Saito, M.; Dyhrman, S.; Eren, A. M.; Moran, M. A.; Braakman, R.

10.1101/2024.01.16.575828 — bioinformatics — Posted on 2024-01-17

2212 DrivR-Base: A Feature Extraction Toolkit For Variant Effect Prediction Model Construction

Francis, A.; Campbell, C.; Gaunt, T. R.

10.1101/2024.01.16.575859 — bioinformatics — Posted on 2024-01-17

2213 ProteinMPNN Recovers Complex Sequence Properties of Transmembrane β-Barrels

Dolorfino, M. D.; Vorobieva, A. A.

10.1101/2024.01.16.575764 — bioinformatics — Posted on 2024-01-17

2214 Beyond Life: Exploring Hemodynamic Patterns in Postmortem Mice Brains

Sdobnov, A.; Piavchenko, G.; Tsytsarev, V.; Bykov, A.; Meglinski, I.

10.1101/2024.01.16.575850 — bioengineering — Posted on 2024-01-17

2215 Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

Milanes, J. E.; Yan, V. C.; Pham, C.-D.; Muller, F. L.; Kwain, S.; Rees, K. C.; Dominy, B. N.; Whitehead, D. C.; Millward, S. W.; Bolejack, M.; Abendroth, J.; Phan, I. Q.; Staker, B.; Moseman, E. A.; Zhang, X.; Ma, X.; Jebet, A.; Yin, X.; Morris, J.

10.1101/2024.01.16.575558 — biochemistry — Posted on 2024-01-17

2216 Genomic evidence for supergene control of Darwin's 'complex marriage arrangement' - the tristylous floral polymorphism

Xue, H.; Gong, Y.; Wright, S. I.; Barrett, S. C. H.

10.1101/2024.01.15.575583 — evolutionary biology — Posted on 2024-01-17

2217 Empirical evidence of resource dependent evolution of payoff matrices in Saccharomyces cerevisiae populations.

Venkataraman, P.; Mahilkar, A.; Raj, N.; Saini, S.

10.1101/2024.01.15.575778 — evolutionary biology — Posted on 2024-01-17

2218 Wastelands or Preferred-lands? Indicators for redefining Desert conservation

Mukherjee, M.; Banerjee, D.; Sharma, I.; Mukerji, M.

10.1101/2024.01.16.575797 — ecology — Posted on 2024-01-17

2219 Nonnative Fish in the Pearl River Delta: A Comprehensive Study on Their Salinity Adaptability and Potential Distribution Area in Brackish Water

Luo, D.; Yang, D.; Li, Y.; Li, J.

10.1101/2024.01.16.575818 — ecology — Posted on 2024-01-17

2220 The human complement factor B-C3b complex: Investigation of the interaction using C3b bound to thiol-Sepharose

Williams, S.; Pondman, K.; Varghese, P.; Al Aiyan, A.; Kishore, U.; Sim, R. B.

10.1101/2024.01.16.575844 — immunology — Posted on 2024-01-17

2221 Evidence of interplays between the vascular and nociceptive systems revealed by changes in capsaicin pain caused by limb position change

Courtin, A. S.; Knaepen, C.; Mouraux, A.; van Neerven, S. G. A.

10.1101/2024.01.16.575811 — neuroscience — Posted on 2024-01-17

2222 LysM-RLK plays an ancestral symbiotic function in plants

Teyssier, E.; Grat, S.; Rich, M. K.; Delaux, P.-M.; Mbengue, M.

10.1101/2024.01.16.575821 — plant biology — Posted on 2024-01-17

2223 Root-specific secondary metabolism at the single-cell level: a case study of theanine metabolism and regulation in the roots of tea plants (Camellia sinensis)

Lin, S.; Zhang, Y.; Zhang, S.; Wei, Y.; Han, M.; Deng, Y.; Guo, J.; Zhu, B.; Yang, T.; Xia, E.; Wan, X.; Lucas, W.; Zhang, Z.

10.1101/2024.01.16.575853 — plant biology — Posted on 2024-01-17

2224 Dissecting the molecular puzzle of the editosome core in Arabidopsis organelles

Baudry, K.; Monachello, D.; Castandet, B.; Majeran, W.; Lurin, C.

10.1101/2024.01.16.575875 — plant biology — Posted on 2024-01-17

2225 MAPK activity and MAP kinase phosphatase 2 (AtMKP2) protein stability under altered glutathione homeostasis in Arabidopsis thaliana

Yang, Y.; Matern, S.; Steininger, H.; Vinde, M. H.; Rausch, T.; Peskan-Berghoefer, T.

10.1101/2024.01.15.575793 — plant biology — Posted on 2024-01-17

2226 Concerted Transport and Phosphorylation of Diacylglycerol at ER-PM Contacts Sites Regulates Phospholipid Dynamics During Stress

Garcia-Hernandez, S.; Haslam, R.; Moya Cuevas, J.; Catala, R.; Michaelson, L.; Amorim-Silva, V.; Markovic, V.; Salinas, J.; Napier, J.; Jaillais, Y.; Ruiz-Lopez, N.; Botella, M. A.

10.1101/2024.01.16.575708 — plant biology — Posted on 2024-01-17

2227 Conservation of symbiotic signalling across 450 million years of plant evolution

Vernie, T.; Rich, M. K.; Pellen, T.; Teyssier, E.; Garrigues, V.; Chauderon, L.; Medioni, L.; van Beveren, F.; Libourel, C.; Keller, J.; Girou, C.; Lefort, C.; Le Ru, A.; Reinhardt, D.; Kodama, K.; Shimazaki, S.; Morel, P.; Kyozuka, J.; Mbengue, M.; Vandenbussche, M.; Delaux, P.-M.

10.1101/2024.01.16.575147 — plant biology — Posted on 2024-01-17

2228 Genome assembly of the rare and endangered Grantham's camellia, Camellia granthamiana

10.1101/2024.01.15.575486 — plant biology — Posted on 2024-01-17

2229 Changes in surface temperatures reveal the thermal challenge associated with catastrophic moult in captive Gentoo penguins

Lewden, A.; Halna du Fretay, T.; Stier, A.

10.1101/2024.01.16.575878 — physiology — Posted on 2024-01-17

2230 Polymeric nanoparticles delivery of AMPK activator 991 prevents its toxicity and improves muscle homeostasis in Duchenne Muscular Dystrophy

Andreana, I.; Kneppers, A.; Ben Larbi, S.; Tifni, F.; Fessard, A.; Sidi-Boumedine, J.; Kryza, D.; Stella, B.; Bordes, C.; Arpicco, S.; Chevalier, Y.; Chazaud, B.; Mounier, R.; Lollo, G.; Juban, G.

10.1101/2024.01.16.575840 — pathology — Posted on 2024-01-17

2231 Advancing the Application of pXRF for Biological Samples

Brandis, K.; Francis, R.

10.1101/2024.01.16.575873 — biochemistry — Posted on 2024-01-17

2232 Cost-Effective Approaches to Elucidate Intergeneric Relationships of Plants: Utilizing Multiple Conserved Nuclear Genes and Whole Chloroplast Genomes

Witharana, E. P.; San, M. H.; Jayawardana, N. U.; Kotoda, N.; Yamamoto, M.; Nagano, Y.

10.1101/2024.01.15.575800 — genomics — Posted on 2024-01-17

2233 Chromosome-level genome assembly of the common chiton, Liolophura japonica (Lischke, 1873)

10.1101/2024.01.15.575488 — genomics — Posted on 2024-01-17

2234 Plant kleptomaniacs: geographic genetic patterns in the amphi-apomictic Rubus ser. Glandulosi (Rosaceae) reveal complex reticulate evolution of Eurasian brambles

Sochor, M.; Sarhanova, P.; Duchoslav, M.; Konecna, M.; Hrones, M.; Travnicek, B.

10.1101/2024.01.16.575855 — evolutionary biology — Posted on 2024-01-17

2235 eDITH: an R-package to spatially project eDNA-based biodiversity across river networks with minimal prior information

Carraro, L.; Altermatt, F.

10.1101/2024.01.16.575835 — ecology — Posted on 2024-01-17

2236 Single-cell RNA sequencing reveals recruitment of the M2-like CCL8high macrophages in Lewis lung carcinoma-bearing mice following hypofractionated radiotherapy

Yang, H.; Lei, Z.; He, J.; Zhang, L.; Lai, T.; Zhou, L.; Wang, N.; Tang, Z.; Sui, J.; Wu, Y.

10.1101/2024.01.15.575792 — immunology — Posted on 2024-01-17

2237 Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection

Perez-Toledo, M.; Beristain-Covarrubias, N.; Pillaye, J.; Persaud, R. R.; Marcial-Juarez, E.; Jossi, S. E.; Hitchcock, J. R.; Alshayea, A.; Channell, W. M.; Lamerton, R. E.; Kavanagh, D. P.; Carestia, A.; Horsnell, W. G.; Henderson, I. R.; Mackman, N.; Clark, A. R.; Jenne, C. N.; Rayes, J.; Watson, S. P.; Cunningham, A. F.

10.1101/2024.01.16.575813 — immunology — Posted on 2024-01-17

2238 Chromosome-scale genome assembly of bread wheat's wild relative Triticum timopheevii

Grewal, S.; Yang, C.; Scholefield, D.; Ashling, S.; Ghosh, S.; Swarbreck, D.; Collins, J.; Yao, E.; Sen, T. Z.; Wilson, M.; Yant, L.; King, I. P.; King, J.

10.1101/2024.01.16.575864 — plant biology — Posted on 2024-01-17

2239 DepoScope: accurate phage depolymerase annotation and domain delineation using large language models

Concha-Eloko, R.; Stock, M.; De Baets, B.; Briers, Y.; Sanjuan, R.; Domingo-Calap, P.; Boeckaerts, D.

10.1101/2024.01.15.575807 — bioinformatics — Posted on 2024-01-17

2240 Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species

Mazzamurro, F.; Chirakadavil, J. B.; Durieux, I.; Poire, L.; Plantade, J.; Ginevra, C.; Jarraud, S.; Wilharm, G.; Charpentier, X.; Rocha, E. P. C.

10.1101/2023.11.06.565790 — genomics — Posted on 2024-01-17

2241 Mono-methylated histones control PARP-1 in chromatin and transcription

Bamgbose, G. G.; Bordet, G.; Lodhi, N.; Tulin, A.

10.1101/2023.11.22.568326 — genetics — Posted on 2024-01-17

2242 Modeling the critical MCOR-causing deletion in mouse unveils aberrant Sox21 expression in developing and adult iris and ciliary body, and implicates Tgfb2 in MCOR-associated glaucoma and myopia.

Angee, C.; Erjavec, E.; Hadjadj, D.; Passet, B.; David, P.; Kostic, C.; Dode, E.; Zanlonghi, X.; Cagnard, N.; Nedelec, B.; Crippa, S.; Bole-Feysot, C.; Zarhrate, M.; Castille, J.; Vilotte, J.-L.; Calvas, P.; Plaisancie, J.; Chassaing, N.; Kaplan, J.; Rozet, J.-M.; Fares Taie, L.

10.1101/2023.12.11.571097 — genetics — Posted on 2024-01-17

2243 Fixation times of de novo and standing beneficial variants in subdivided populations

Sudbrack, V.; Mullon, C.

10.1101/2023.07.07.548167 — evolutionary biology — Posted on 2024-01-17

2244 Increased positive selection in highly recombining genes is not an evidence for an evolutionary advantage of recombination

Joseph, J.

10.1101/2024.01.16.575829 — evolutionary biology — Posted on 2024-01-17

2245 Liming pasture soils in the Amazon region promotes low-affinity methane oxidation by type I and II methanotrophs

Fonseca de Souza, L.; Nakamura, F. M.; Kroeger, M.; Obregon, D.; de Moraes, M. T.; Vicente, M. G.; Moreira, M. Z.; Pellizari, V. H.; Tsai, S. M.; Nusslein, K.

10.1101/2024.01.16.575838 — ecology — Posted on 2024-01-17

2246 RNA-RNA interactions between Respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunity

Ressel, S.; Kumar, S.; Bermudez-Barrientos, J. R.; Gordon, K.; Lane, J.; Wu, J.; Abreu-Goodger, C.; Schwarze, J.; Buck, A. H.

10.1101/2023.06.05.543706 — molecular biology — Posted on 2024-01-17

2247 TEAD1 is crucial for developmental myelination, Remak bundles and functional regeneration of peripheral nerves

Grove, M.; Kim, H.; Pang, S.; Amaya, J. P.; Hu, G.; Zhou, J.; Lemay, M.; Son, Y.-J.

10.1101/2023.02.27.530298 — neuroscience — Posted on 2024-01-17

2248 Evolution shapes metabolic function and niche-specific antimicrobial targets in pathobionts

Glass, E. M.; Dillard, L. R.; Kolling, G. L. L.; Warren, A. S.; Papin, J. A.

10.1101/2022.11.10.515998 — systems biology — Posted on 2024-01-17

2249 Mitigating reactive oxygen species production and increasing gel porosity improves lymphocyte motility and fibroblast spreading in photocrosslinked gelatin-thiol hydrogels

Ozulumba, T.; Zatorski, J. M.; Arneja, A.; Hammel, J. H.; Braciale, T. J.; Luckey, C. J.; Munson, J. M.; Pompano, R. R.

10.1101/2024.01.14.574282 — bioengineering — Posted on 2024-01-17

2250 Flap endonuclease Substrate Interactions studied using Dynamic Single-Molecule Atomic Force Microscopy

Verma, V.; Brudenell, E. L.; Cussons, S.; Phipps, J.; Kong, S. C.; Sayers, J. R.; Hobbs, J. K.

10.1101/2024.01.10.574983 — biochemistry — Posted on 2024-01-17

2251 Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells

Grenell, A. B.; Singh, C.; Raju, M.; Wolk, A.; Dalvi, S.; Jang, G.-F.; Crabb, J. S.; Hershberger, C. E.; Manian, K. V.; Crabb, J. W.; Singh, R.; Du, J.; Anand-Apte, B.

10.1101/2024.01.05.574411 — biochemistry — Posted on 2024-01-17

2252 Can mechanistic constraints on recombination reestablishment explain the long-term maintenance of degenerate sex chromosomes?

Lenormand, T.; Roze, D.

10.1101/2023.02.17.528909 — evolutionary biology — Posted on 2024-01-17

2253 rsofun v4.4.1: A model-data integration framework for simulating ecosystem processes

Aran Paredes, J.; Hufkens, K.; Stocker, B. D.

10.1101/2023.11.24.568574 — ecology — Posted on 2024-01-17

2254 Drosophila Asap regulates cellular protrusions via dArf6-dependent actin regulatory pathway

Kushwaha, S.; Mallik, B.; Mushtaq, Z.; Bisht, A.; Kumar, V.

10.1101/2024.01.17.575521 — cell biology — Posted on 2024-01-17

2255 Stimulation of NCAM1-14.3.3.ζδ-derived Peptide Interaction Fuels Angiogenesis and Osteogenesis in Ageing

Kusumbe, A.; Yesin, T.; Liu, H.; Ding, Z.; Singh, A.; Zhang, Y.; Chen, J.

10.1101/2024.01.16.575939 — cell biology — Posted on 2024-01-17

2256 IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport

Anitei, M.; Bruno, F.; Valkova, C.; Cirri, E.; Dau, T.; Mestres Lascano, I.; Calegari, F.; Kaether, C.

10.1101/2024.01.17.576044 — cell biology — Posted on 2024-01-17

2257 Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis

Joshi, D.; Coon, B. G.; Chakraborty, R.; Deng, H.; Fernandez Tussy, P.; Meredith, E.; Traylor, J. G.; Orr, A. W.; Fernandez-Hernando, C.; Schwartz, M. A.

10.1101/2024.01.16.575958 — cell biology — Posted on 2024-01-17

2258 The RNA polymerase II general transcription factor TFIIB is a target for transcriptome control during cellular stress and viral infection

Gulyas, L.; Glaunsinger, B.

10.1101/2024.01.16.575933 — cell biology — Posted on 2024-01-17

2259 Substrate elasticity does not impact on DNA methylation changes during differentiation of pluripotent stem cells

Elsafi Mabrouk, M. H.; Zeevaert, K.; Henneke, A.-C.; Maassen, C.; Wagner, W.

10.1101/2024.01.16.575833 — cell biology — Posted on 2024-01-17

2260 Ciliary length regulation by intraflagellar transport in zebrafish

Sun, Y.; Chen, Z.; Jin, M.; Xie, H.; Zhao, C.

10.1101/2024.01.16.575975 — cell biology — Posted on 2024-01-17

2261 PIEZO1-mediated mechanosensing governs NK cell killing efficiency and infiltration in three-dimensional matrices

Yanamandra, A. K.; Zhang, J.; Montalvo, G.; Zhou, X.; Biedenweg, D.; Zhao, R.; Sharma, S.; Hoth, M.; Lautenschlaeger, F.; Otto, O.; del Campo, A.; Qu, B.

10.1101/2023.03.27.534435 — immunology — Posted on 2024-01-17

2262 Timing and location of speech errors induced by direct cortical stimulation

Kabakoff, H.; Yu, L.; Friedman, D.; Dugan, P.; Doyle, W.; Devinsky, O.; Flinker, A.

10.1101/2023.09.14.557732 — neuroscience — Posted on 2024-01-17

2263 Neuronal polyunsaturated fatty acids are protective in FTD/ALS

Giblin, A.; Cammack, A. J.; Blomberg, N.; Mikheenko, A.; Carcole, M.; Coneys, R.; Zhou, L.; Mohammed, Y.; Olivier-Jimenez, D.; Atilano, M. L.; Niccoli, T.; Coyne, A. N.; van der Kant, R.; Lashley, T.; Giera, M.; Partridge, L.; Isaacs, A. M.

10.1101/2024.01.16.575677 — neuroscience — Posted on 2024-01-17

2264 Decoding kinematic information from beta-band motor rhythms of speech motor cortex: A methodological/analytic approach using concurrent speech movement tracking and magnetoencephalography

Anastasopoulou, I.; Cheyne, D. O.; Lieshout, P. v.; Johnson, B. W.

10.1101/2023.06.12.544529 — neuroscience — Posted on 2024-01-17

2265 Distinct patterns of connectivity with motor cortex reflect component processes of sensorimotor learning

Areshenkoff, C. N.; de Brouwer, A. J.; Gale, D. J.; Nashed, J. Y.; Smallwood, J.; Flanagan, J. R.; Gallivan, J. P.

10.1101/2023.07.01.547344 — neuroscience — Posted on 2024-01-17

2266 Conserved amino acid residues and gene expression patterns associated with the substrate preferences of the competing enzymes FLS and DFR

Choudhary, N.; Pucker, B.

10.1101/2023.11.05.565693 — plant biology — Posted on 2024-01-17

2267 Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

Brumbaugh-Reed, E. H.; Aoki, K.; Toettcher, J. E.

10.1101/2024.01.16.575860 — bioengineering — Posted on 2024-01-17

2268 CRISPR-Cas12a exhibits metal-dependent specificity switching

Nguyen, G. T.; Schelling, M. A.; Buscher, K. A.; Sritharan, A.; Sashital, D. G.

10.1101/2023.11.29.569287 — biochemistry — Posted on 2024-01-17

2269 Synthetic Eco-Evolutionary Dynamics in Simple Molecular Environment

Casiraghi, L.; Mambretti, F.; Tovo, A.; Paraboschi, E. M.; Suweis, S.; Bellini, T.

10.1101/2023.07.21.549992 — ecology — Posted on 2024-01-17

2270 A Clock and Wavefront Self-Organizing Model Recreates the Dynamics of Mouse Somitogenesis in-vivo and in-vitro

Klepstad, J.; Marcon, L.

10.1101/2023.01.18.524516 — developmental biology — Posted on 2024-01-17

2271 Quantification of cellular phototoxicity of organelle stains by the dynamics of microtubule polymerization

Mahapatra, S.; Ma, S.; Dong, B.; Zhang, C.

10.1101/2024.01.17.576021 — cell biology — Posted on 2024-01-17

2272 Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

Yamanaka, T.; Xiao, Z.; Tsujita, N.; Awad, M.; Umehara, T.; Shimada, M.

10.1101/2024.01.16.575926 — cell biology — Posted on 2024-01-17

2273 Structural basis of respiratory complexes adaptation to cold temperatures

Shin, Y.-C.; Latorre-Muro, P.; Djurabekova, A.; Zdorevskyi, O.; Bennett, C.; Burger, N.; Song, K.; Xu, C.; Sharma, V.; Liao, M.; Puigserver, P.

10.1101/2024.01.16.575914 — cell biology — Posted on 2024-01-17

2274 Mannose Supplementation Curbs Liver Steatosis and Fibrosis in Murine MASH by Inhibiting Fructose Metabolism

Hong, J.; Carbajal, Y.; Trotman, J.; Glass, M.; Sclar, V.; Alter, I. L.; Zhang, P.; Wang, L.; Chen, L.; Petitjean, M.; Friedman, S. L.; DeRossi, C.; Chu, J.

10.1101/2024.01.17.576067 — cell biology — Posted on 2024-01-17

2275 Key role of vimentin in the organization of the primary cilium

Lalioti, V.; Moneo-Corcuera, D.; Perez-Sala, D.

10.1101/2024.01.17.576004 — cell biology — Posted on 2024-01-17

2276 The RecBC complex protects single-stranded DNA gaps during lesion bypass

Philippin, G.; Le Cam, E.; Chrabaszcz, E.; Iturralde, M.; Modesti, M.; Dupaigne, P.; Pages, V.; Laureti, L.

10.1101/2023.09.04.556180 — molecular biology — Posted on 2024-01-17

2277 Regulation of potassium homeostasis in Caulobacter crescentus

Quintero-Yanes, A.; Leger, L.; Collignon, M.; Mignon, J.; Mayard, A.; Michaux, C.; Hallez, R.

10.1101/2023.07.05.547876 — microbiology — Posted on 2024-01-17

2278 Atypical Biological Motion Perception in Children with Attention Deficit Hyperactivity Disorder: Dissociating the Roles of Local Motion and Global Configuration Processing

Tian, J.; Yang, F.; Wang, Y.; Wang, L.; Wang, N.; Jiang, Y.; Yang, L.

10.1101/2023.07.25.550597 — neuroscience — Posted on 2024-01-17

2279 FeS-cluster coordination of vertebrate thioredoxin regulates suppression of hypoxia-induced factor 2α through iron regulatory protein 1

Berndt, C.; Hanschmann, E.-M.; Jordt, L. M.; Gellert, M.; Thewes, L.; Ortegon Salas, C.; Poschmann, G.; Mueller, C. S.; Bodnar, Y.; Schippers, S.; Handorf, O.; Nowack, R.; Moulis, J.-M.; Schulzke, C.; Schuenemann, V.; Lillig, C. H.

10.1101/2020.08.04.235721 — biochemistry — Posted on 2024-01-17

2280 Arl2 Associates with Cdk5rap2 to Regulate Cortical Development via Microtubule Organization

Ma, D.; Lin, K.-Y.; Divya, S.; Lin, J.; Gujar, M. R.; Aung, H. Y.; Tan, Y. S.; Gao, Y.; Vincent, A. S.; Chen, T.; Wang, H.

10.1101/2024.01.16.575964 — neuroscience — Posted on 2024-01-17

2281 Nuclear pores as conduits for fluid flow during osmotic stress

Hoffmann, P. C.; Kim, H.; Obarska-Kosinska, A.; Kreysing, J. P.; Andino-Frydman, E.; Cruz-Leon, S.; Cernikova, L.; Kosinski, J.; Turonova, B.; Hummer, G.; Beck, M.

10.1101/2024.01.17.575985 — cell biology — Posted on 2024-01-17

2282 Rotten to the core - a neurofunctional signature of subjective core disgust generalizes to oral distaste and socio-moral contexts

Gan, X.; Zhou, F.; Xu, T.; Liu, X.; Zhang, R.; Zheng, Z.; Yang, X.; Zhou, X.; Yu, F.; Li, J.; Cui, R.; Wang, L.; Yuan, J.; Yao, D.; Becker, B.

10.1101/2023.05.18.541259 — neuroscience — Posted on 2024-01-17

2283 The evolution of transposable elements in Brachypodium distachyon is governed by purifying selection, while neutral and adaptive processes play a minor role

Horvath, R.; Minadakis, N.; Bourgeois, Y. X. C.; Roulin, A.

10.1101/2023.09.15.557873 — evolutionary biology — Posted on 2024-01-17

2284 Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

Benitiere, F.; Necsulea, A.; Duret, L.

10.1101/2022.12.09.519597 — evolutionary biology — Posted on 2024-01-17

2285 Extracellular Histones Promote Calcium Phosphate-Dependent Calcification in Mouse Vascular Smooth Muscle Cells

Hoshino, T.; Kharaghani, D.; Kohno, S.

10.1101/2023.08.31.555403 — cell biology — Posted on 2024-01-17

2286 Mapping axon diameters and conduction velocity in the rat brain - different methods tell different stories of the structure-function relationship

Skoven, C. S.; Andersson, M.; Pizzolato, M.; Siebner, H. R.; Dyrby, T. B.

10.1101/2023.10.20.558833 — neuroscience — Posted on 2024-01-17

2287 Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner

Zhao, X.; Chae, Y.; Smith, D.; Chen, V.; DeFelipe, D.; Sokol, J. W.; Sadangi, A.; Tschida, K.

10.1101/2023.11.20.567901 — neuroscience — Posted on 2024-01-17

2288 Potassium-mediated bacterial chemotactic response

Zhang, C.; Zhang, R.; Yuan, J.

10.1101/2023.08.29.555418 — biophysics — Posted on 2024-01-17

2289 An Efficient Computational Method to Simulate Autosomal Chromosomes with Trisomy Aberrations

Nguyen Huy, T.; Nguyen, H. V.; Pham, M. D.; Le, V. S.

10.1101/2023.11.24.568620 — bioinformatics — Posted on 2024-01-17

2290 Four-Core Genotypes mice harbour a 3.2MB X-Y translocation that perturbs Tlr7 dosage

Panten, J.; Del Prete, S.; Cleland, J. P.; Saunders, L. M.; van Riet, J.; Schneider, A.; Ginno, P. A.; Schneider, N.; Koch, M.-L.; Gerstung, M.; Stegle, O.; Turner, J. M. A.; Heard, E.; Odom, D. T.

10.1101/2023.12.04.569933 — genetics — Posted on 2024-01-17

2291 Assessing the dynamics of Mycobacterium bovis infection in three French badger populations

Calenge, C.; Payne, A.; Reveillaud, E.; Richomme, C.; Girard, S.; Desvaux, S.

10.1101/2023.05.31.543041 — ecology — Posted on 2024-01-17

2292 Anticipatory Emotions and Academic Performance: The Role of Boredom in a Preservice Teachers' Lab Experience

Ochoa de Alda, J. A. G.; Marcos-Merino, J. M.; Valares-Masa, C.; Esteban-Gallego, R.

10.1101/2024.01.16.575518 — scientific communication and education — Posted on 2024-01-17

2293 An Early Miocene skeleton of Brachydiceratherium Lavocat, 1951 (Mammalia, Perissodactyla) from the Baikal area, Russia, and a revised phylogeny of Eurasian teleoceratines

Sizov, A.; Klementiev, A.; Antoine, P.-O.

10.1101/2022.07.06.498987 — paleontology — Posted on 2024-01-17

2294 Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough

Pavlikova, Z. C.; Miletinova, P.; Pospisilova, K.; Roithova, A.; Zahonova, K.; Kachale, A.; Becker, T.; Durante, I.; Lukes, J.; Paris, Z.; Beznoskova, P.; Valasek, L. S.

10.1101/2023.06.19.543857 — molecular biology — Posted on 2024-01-17

2295 DUALISTIC SAHA DOSE-DEPENDENT EFFECTS ON GLIAL-INFLAMMATORY RESPONSE

Mancino, S.; Boraso, M.; Galmozzi, A.; De Fabiani, E. S. R.; Crestani, M.; Viviani, B.

10.1101/2024.01.16.575689 — molecular biology — Posted on 2024-01-17

2296 Monocyte-derived fibrocytes contribute to nucleus pulposus fibrosis and intervertebral disc degeneration

Sun, Y.; Su, Z.; Peng, Y.; So, K. K.; Lu, Q.; Lyu, M.; Huang, Y.; Guan, Z.; Zheng, Z.; Zuo, J.; Cheung, K. M.; Zhang, X.; Leung, V. Y.

10.1101/2024.01.16.575808 — physiology — Posted on 2024-01-17

2297 Proteomic analysis revealed the function of PoElp3 in development, pathogenicity, and autophagy through the tRNA-mediated translation efficiency in the rice blast fungus

Liu, Y.; Sun, T.; Li, Y.; Wang, X.; Huang, J.; Bai, H.; Hu, J.; Zhang, Z.; Li, X.; Wang, Z.; Zheng, H.; Lin, G.

10.1101/2023.07.19.548190 — pathology — Posted on 2024-01-17

2298 The Parkinson's Disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress

McCarron, K. R.; Elcocks, H.; Mortiboys, H. J.; Urbe, S.; Clague, M. J.

10.1101/2023.12.02.569621 — cell biology — Posted on 2024-01-17

2299 5-Fluorouracil Treatment Represses Pseudouridine-Containing Small RNA Export into Extracellular Vesicles

Qu, S.; Nelson, H.; Liu, X.; Semler, E.; Michell, D. L.; Massick, C.; Franklin, J. L.; Karijolich, J.; Weaver, A. M.; Coffey, R. J.; Liu, Q.; Vickers, K.; Patton, J. G.

10.1101/2024.01.15.575751 — molecular biology — Posted on 2024-01-17

2300 Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

Panda, S.; Jayasinghe, Y. P.; Shinde, D. D.; Bueno, E.; Stastny, A.; Bertrand, B. P.; Chaudhari, S. S.; Kielian, T.; Cava, F.; Ronning, D. R.; Thomas, V. C.

10.1101/2024.01.15.575639 — microbiology — Posted on 2024-01-17

2301 LizardNet: A mobile hybrid deep learning tool for classification of 3D representations of Amazonian lizards

da Silva, A. G.; de Oliveira, R. P.; de Carvalho, E. A.; Bastos, C. d. O.; Gomes, B. D.

10.1101/2024.01.15.575627 — systems biology — Posted on 2024-01-17

2302 An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries

Petersen, B. M.; Kirby, M.; Chrispens, K.; Irvin, O.; Strawn, I.; Haas, C.; Walker, A.; Baumer, Z. T.; Ulmer, S.; Ayala, E.; Irvin, O.; Rhodes, E. R.; Guthmiller, J.; Steiner, P. J.; Whitehead, T. A.

10.1101/2024.01.16.575852 — biochemistry — Posted on 2024-01-17

2303 Bacterial exonuclease III expands its enzymatic activities on single-stranded DNA

Wang, H.; Ye, C.; Lu, Q.; Jiang, Z.; Jiang, C.; Zhou, C.; Li, N.; Zhang, C.; Zhao, G.; Yue, M.; Li, Y.

10.1101/2024.01.13.575533 — biochemistry — Posted on 2024-01-17

2304 Annexin A1, Calreticulin and High Mobility Group Box 1 are elevated in Secondary Progressive Multiple Sclerosis: Does Immunogenic Cell Death Occur in Multiple Sclerosis?

Hejazi, M. S.; Jafari, S.; Montazersaheb, S.; Molavi, O.; Hoseini, V.; Talebi, M.; Nikanfar, M.

10.1101/2024.01.12.575470 — immunology — Posted on 2024-01-17

2305 The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling

Matos-Filipe, P.; Garcia-Illarramendi, J. M.; Jorba, G.; Oliva, B.; Farres, J.; Mas, J. M.

10.1101/2022.11.10.515995 — bioinformatics — Posted on 2024-01-17

2306 In-depth characterisation of a selection of gut commensal bacteria reveals their functional capacities to metabolise dietary carbohydrates with prebiotic potential

Cassandre, B.-F.; Paul, B.; Frederic, P.; Sarah, V.; Cyril, C.; Florence, C.; Celine, C.; Olivier, R.; Christelle, H.-A.; Philippe, L.; Cherbuy, C.

10.1101/2024.01.16.575889 — microbiology — Posted on 2024-01-17

2307 Gaze and Arrows: does the Gaze Following Patch in the posterior temporal cortex differentiate social and symbolic spatial cues?

Gorner, M.; Ramezanpour, H.; Dicke, P. W.; Thier, P.

10.1101/2024.01.15.575547 — neuroscience — Posted on 2024-01-17

2308 Cell-type specific optogenetic fMRI on basal forebrain reveals functional network basis of behavioral preference

Zou, Y.; Tong, C.; Peng, W.; Qiu, Y.; Li, J.; Xia, Y.; Pei, M.; Zhang, K.; Li, W.; Xu, M.; Liang, Z.

10.1101/2023.07.06.548057 — neuroscience — Posted on 2024-01-17

2309 Improving the performance of supervised deep learning for regulatory genomics using phylogenetic augmentation

Duncan, A. G.; Mitchell, J. A.; Moses, A. M.

10.1101/2023.09.15.558005 — bioinformatics — Posted on 2024-01-17

2310 A General-Purpose Non-invasive Neurotechnology Research Platform

Schalk, G.; Shao, S.; Xiao, K.; Li, J.; Xie, J.; Guan, Y.; Wu, Z.; Chen, L.; Zhong, X.; Xu, C.; Li, G.; Yu, H.

10.1101/2024.01.01.573494 — bioengineering — Posted on 2024-01-17

2311 Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups

Nguyen, D. T.; Zhu, L.; Gray, D. L.; Woods, T.; Padhi, C.; Flatt, K. M.; Mitchell, D. A.; van der Donk, W. A.

10.1101/2023.10.30.564719 — biochemistry — Posted on 2024-01-17

2312 Contextualising samples: Supporting reference genomes of European biodiversity through sample and associated metadata collection

Boehne, A.; Fernandez, R.; Leonard, J. A.; McCartney, A. M.; McTaggart, S.; Melo-Ferreira, J.; Monteiro, R.; Oomen, R. A.; Vinnere Pettersson, O.; Struck, T. H.

10.1101/2023.06.28.546652 — genomics — Posted on 2024-01-17

2313 Low-frequency somatic mutations are heritable in tropical trees Dicorynia guianensis and Sextonia rubra

Schmitt, S.; Heuret, P.; Troispoux, V.; Beraud, M.; Cazal, J.; Chancerel, E.; Cravero, C.; Guichoux, E.; Lepais, O.; Loureiro, J.; Marande, W.; Martin-Ducup, O.; Vincent, G.; Chave, J.; Plomion, C.; Leroy, T.; Heuertz, M.; Tysklind, N.

10.1101/2023.06.05.543657 — genomics — Posted on 2024-01-17

2314 Can mechanistic constraints on recombination reestablishment explain the long-term maintenance of degenerate sex chromosomes?

Lenormand, T.; Roze, D.

10.1101/2023.02.17.528909 — evolutionary biology — Posted on 2024-01-17

2315 Improved Estimation of Bird Abundance and Energy Consumption by Combining Point and Transect Observations

Thron, C.; Santillan, V.; Quitian, M.; Neuschulz, E. L.; Schleuning, M.; Boehning-Gaese, K.; Brothers, A.; Bolagay, M. J. A.; Alvarez, O.

10.1101/2023.08.21.554181 — ecology — Posted on 2024-01-17

2316 The medial entorhinal cortex encodes multisensory spatial information

Nguyen, D.; Wang, G.; Gu, Y.

10.1101/2024.01.09.574924 — neuroscience — Posted on 2024-01-17

2317 Proteomic evidence of astrocytic dysfunction in the olfactory bulb of depressed suicides

Rahimian, R.; Perlman, K.; Fakhfouri, G.; Mpai, R.; Richard, V. R.; Hercher, C.; Penney, L.; Davoli, M. A.; Nagy, C.; Zahedi, R. P.; Borchers, C. H.; Giros, B.; Turecki, G.; Mechawar, N.

10.1101/2023.10.29.564604 — neuroscience — Posted on 2024-01-17

2318 Axon arrival times and physical occupancy establish visual projection neuron integration on developing dendrites in the Drosophila optic glomeruli.

McFarland, B. W.; Jang, H.; Smolin, N.; Hina, B. W.; Parisi, M. J.; Davis, K. C.; Mosca, T. J.; Godenschwege, T. A.; Nern, A.; Kurmangaliyev, Y. Z.; von Reyn, C. R.

10.1101/2022.08.20.504653 — neuroscience — Posted on 2024-01-17

2319 Functional connectivity across the human subcortical auditory system using an autoregressive matrix-Gaussian copula graphical model approach with partial correlations

Chandra, N.; Sitek, K. R.; Chandresekaran, B.; Sarkar, A.

10.1101/2022.09.15.508099 — neuroscience — Posted on 2024-01-17

2320 Not fleeting but lasting: Limited influence of aging on implicit adaptative motor learning and its short-term retention.

Hermans, P.; Vandevoorde, K.; Orban de Xivry, J.-J.

10.1101/2023.08.30.555501 — neuroscience — Posted on 2024-01-17

2321 Graph Learning for Cortical Parcellation from Tensor Decompositions of Resting-State fMRI

Liu, Y.; Li, J.; Wisnowski, J. L.; Leahy, R. M.

10.1101/2024.01.05.574423 — neuroscience — Posted on 2024-01-17

2322 Neural geometrodynamics, complexity, and plasticity: a psychedelics perspective

Ruffini, G.; Lopez-Sola, E.; Vohryzek, J.; Sanchez-Todo, R.

10.1101/2023.08.14.553258 — neuroscience — Posted on 2024-01-17

2323 Structure and function of bacterial YeeE-YeeD complex in thiosulfate uptake pathway

Ikei, M.; Miyazaki, R.; Monden, K.; Naito, Y.; Takeuchi, A.; Takahashi, Y. S.; Tanaka, Y.; Murata, K.; Mori, T.; Ichikawa, M.; Tsukazaki, T.

10.1101/2023.07.28.550924 — biochemistry — Posted on 2024-01-17

2324 Single cell omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveals heterogeneity of endothelial subtype and response to activating perturbations

Adelus, M. L.; Ding, J.; Tran, B. T.; Conklin, A. C.; Golebiewski, A. K.; Stolze, L. K.; Whalen, M. B.; Cusanovich, D.; Romanoski, C. E.

10.1101/2023.04.03.535495 — genomics — Posted on 2024-01-17

2325 Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization

Fukumoto, J.; Yoshida, M.; Tokuoka, S. M.; Hayakawa, E. S. H.; Miyazaki, S.; Sakura, T.; Ken Inaoka, D.; Kita, K.; Usukura, J.; Shindou, H.; Tokumasu, F.

10.1101/2024.01.13.575495 — microbiology — Posted on 2024-01-17

2326 Identifying Developmental Changes in Functional Brain Connectivity Associated with Cognitive Functioning in Children and Adolescents with ADHD

Pho, B.; Stevenson, R.; Mohsenzadeh, Y.; Stojanoski, B.

10.1101/2023.12.20.572617 — neuroscience — Posted on 2024-01-17

2327 Beta2 -Adrenergic Agonists in Treatment for Parkinsonism, with Implications for Neurodegenerative and Neoplastic Disorders.

Inchiosa, M. A.

10.1101/2024.01.12.575406 — pharmacology and toxicology — Posted on 2024-01-17

2328 Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer

Toker, A.; Hillis, A. L.; Martin, T. D.; Manchester, H. E.; Hogstrom, J. M.; Zhang, N.; Lecky, E.; Kozlova, N.; Persky, N. S.; Root, D. E.; Brown, M.; Cichowski, K.; Elledge, S. J.; Muranen, T.; Fruman, D. A.; Barry, S. T.; Clohessy, J. G.; Madsen, R. R.

10.1101/2024.01.16.575899 — cancer biology — Posted on 2024-01-16

2329 Molecular and cellular dynamics of the developing human neocortex at single-cell resolution

Wang, L.; Wang, C.; Moriano, J. A.; Chen, S.; Zhang, S.; Mukhtar, T.; Wang, S.; Cebrian-Silla, A.; Bi, Q.; Augustin, J. J.; de Oliveira, L. G.; Song, M.; Ge, X.; Zuo, G.; Paredes, M. F.; Huang, E. J.; Alvarez-Buylla, A.; Duan, X.; Li, J.; Kriegstein, A. R.

10.1101/2024.01.16.575956 — neuroscience — Posted on 2024-01-16

2330 Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy

Dave, K. M.; Venna, V. R.; Rao, K. S.; Stolz, D. B.; Quaicoe, V. A.; Maniskas, M.; Hildebrand, E. E.; Green, D.; Chen, M.; Milosevic, J.; Zheng, S.-y.; Shiva, S.; McCullough, L. D.; Manickam, D. S.

10.1101/2024.01.16.575903 — bioengineering — Posted on 2024-01-16

2331 FAK and p130Cas modulate stiffness-mediated early transcription and cellular metabolism

Tumenbayar, B.-I.; Tutino, V. M.; Brazzo, J. A.; Yao, P.; Bae, Y.

10.1101/2024.01.15.575789 — genomics — Posted on 2024-01-16

2332 The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences

Brown, G. W.

10.1101/2024.01.15.575754 — genetics — Posted on 2024-01-16

2333 Scaling and merging macromolecular diffuse scattering with mdx2

Meisburger, S. P.; Ando, N.

10.1101/2024.01.16.575887 — biophysics — Posted on 2024-01-16

2334 Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa

He, S.; Taher, N. M.; Hvorecny, K. L.; Ragusa, M. J.; Bahl, C. D.; Hickman, A. B.; Dyda, F.; Madden, D. R.

10.1101/2024.01.16.572601 — biochemistry — Posted on 2024-01-16

2335 SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers

Hosseinpour, M.; Malaver-Ortega, L.; Perlaza-Jimenez, L.; Joo, J. E.; Liu, L.; Caldon, C. E.; Dugue, P.-A.; Dowty, J. G.; Southey, M. C.; Rosenbluh, J.

10.1101/2024.01.16.575955 — genetics — Posted on 2024-01-16

2336 Nobiletin, a Polymethoxyflavonoid, Activates the Desuccinylase Activity of SIRT5 and Prevents the Development of Heart Failure

Sunagawa, Y.; Funamoto, M.; Hamabe-Horiike, T.; Hieda, K.; Yabuki, S.; Tomino, M.; Ikai, Y.; Suzuki, A.; Ogawahara, S.; Yabuta, A.; Sasaki, H.; Ebe, A.; Naito, S.; Takai, H.; Shimizu, K.; Shimizu, S.; Kawase, Y.; Naruta, R.; Katanasaka, Y.; Asakawa, T.; Kan, T.; Mori, K.; Murakami, A.; Ogura, M.; Inagaki, N.; Hasegawa, K.; Morimoto, T.

10.1101/2024.01.16.575602 — molecular biology — Posted on 2024-01-16

2337 Community successional patterns and inter-kingdom interactions during granular biofilm development

de Celis, M.; Modin, O.; Arregui, L.; Persson, F.; Santos, A.; Belda, I.; Wilen, B.-M.; Liebana, R.

10.1101/2024.01.16.575656 — microbiology — Posted on 2024-01-16

2338 Annotation-free prediction of microbial dioxygen utilization

Flamholz, A. I.; Goldford, J. E.; Larsson, E. M.; Jinich, A.; Fischer, W. W.; Newman, D. K.

10.1101/2024.01.16.575888 — microbiology — Posted on 2024-01-16

2339 The coral pathogen Vibrio coralliilyticus utilizes the compatible solute and signaling molecule myo-inositol as a sole carbon source

Boas Lichty, K.; Boyd, E. F.

10.1101/2024.01.16.575920 — microbiology — Posted on 2024-01-16

2340 Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue

Watzlawik, J. O.; Hou, X.; Richardson, T.; Lewicki, S. L.; Siuda, J.; Wszolek, Z. K.; Cook, C. N.; Petrucelli, L.; DeTure, M.; Dickson, D. W.; Antico, O.; Muqit, M.; Fishman, J. B.; Pirani, K.; Kumaran, R.; Polinski, N. K.; Fiesel, F. C.; Springer, W.

10.1101/2024.01.15.575715 — neuroscience — Posted on 2024-01-16

2341 Amygdalo-nigral inputs target dopaminergic and GABAergic neurons in the primate: a view from dendrites and soma

Fudge, J.; Kelly, E. A.; Love, T.

10.1101/2024.01.16.575910 — neuroscience — Posted on 2024-01-16

2342 Genome streamlining to improve performance of a fast-growing cyanobacterium Synechococcus elongatus UTEX 2973

Sengupta, A.; Bandyopadhyay, A.; Sarkar, D.; Hendry, J. I.; Schubert, M. G.; Liu, D.; Church, G.; Maranas, C. D.; Pakrasi, H. B.

10.1101/2024.01.16.575707 — synthetic biology — Posted on 2024-01-16

2343 Influence of bacterial swimming and hydrodynamics on infection by phages

Lohrmann, C.; Holm, C.; Datta, S. S.

10.1101/2024.01.15.575727 — biophysics — Posted on 2024-01-16

2344 Fusion of blood vessel organoids with human pancreatic islets improves insulin response over time.

Tubbs, E.; Mehanovic, M.; Lopes, M.; Quintard, C.; Combe, S.; Armanet, M.; Domet, T.; Sabatier, J.; Granziera, S.; Penninger, J. P.; Freida, D.; Gidrol, X.

10.1101/2024.01.15.575704 — bioengineering — Posted on 2024-01-16

2345 Adaptive thermogenesis is mediated by GDF15 via the GFRAL neuronal axis in mice

Kim, J. E.; Ju, S.-H.; Lee, M.; Hong, H. J.; Yaseen, U.; Zhang, B.; Lee, S. E.; Kang, Y. E.; Kim, J. T.; Yi, H.-S.; Yi, Y.-S.; Jun, S.; Park, M.; Kim, J.; Auwerx, J.; Sohn, J.-W.; Lee, J. H.; Shong, M.

10.1101/2024.01.15.575796 — molecular biology — Posted on 2024-01-16

2346 G-quadruplexes in Haloferax volcanii

Aktary, Z.; Cucchiarini, A.; Vesco, G.; Noury, D.; Jourdain, T.; Verga, D.; Mahou, P.; Olivier, N.; Valkova, N.; Porubiakova, O.; Brazda, V.; Bouvier, M.; Kwapisz, M.; Clouet-d'Orval, B.; Allers, T.; Lestini, R.; Mergny, J.-L.; Guittat, L.

10.1101/2024.01.16.575881 — molecular biology — Posted on 2024-01-16

2347 Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy

Zborowsky, S.; Seurat, J.; Balacheff, Q.; Minh, C. N. N.; Titecat, M.; Evrard, E.; Rodriguez-Gonzalez, R. A.; Marchi, J.; Weitz, J. W.; Debarbieux, L.

10.1101/2024.01.16.575879 — microbiology — Posted on 2024-01-16

2348 Control of iron acquisition by multiple small RNAs unravels a new role for transcriptional terminator loops in gene regulation

Flores, E. S.; Jagodnik, J.; Quenette, F.; Korepanov, A.; Guillier, M.

10.1101/2024.01.16.575843 — microbiology — Posted on 2024-01-16

2349 Forced mouth opening induces post-traumatic hyperalgesia and associated peripheral sensitization after temporomandibular joints injury in mice

Alshanqiti, I.; Son, H.; Shannonhouse, J.; Hu, J.; Kumari, S.; Parastooei, G.; Wang, S.; Ro, J. Y.; Kim, Y. S.; Chung, M.-K.

10.1101/2024.01.16.575891 — neuroscience — Posted on 2024-01-16

2350 Coordinated social interactions are supported by integrated neural representations

Formica, S.; Brass, M.

10.1101/2024.01.16.575885 — neuroscience — Posted on 2024-01-16

2351 Forecasting EEG time series with WaveNet

Pankka, H.; Lehtinen, J.; Ilmoniemi, R.; Roine, T.

10.1101/2024.01.16.575836 — neuroscience — Posted on 2024-01-16

2352 Does early-stage Alzheimer's disease affect the dynamics of motor adaptation?

Sutter, K.; Oostwoud Wijdenes, L.; van Beers, R. J.; Claassen, J. A. H. R.; Kessels, R. P. C.; Medendorp, W. P.

10.1101/2024.01.16.575820 — neuroscience — Posted on 2024-01-16

2353 Uncovering population contributions to the extracellular potential in the mouse visual system using Laminar Population Analysis

Rimehaug, A. E.; Dale, A. M.; Arkhipov, A.; Einevoll, G. T.

10.1101/2024.01.15.575805 — neuroscience — Posted on 2024-01-16

2354 Assessing the relationship between neural entrainment and altered states of consciousness induced by electronic music

Aparicio-Terres, R.; Lopez-Mochales, S.; Diaz-Andreu, M.; Escera, C.

10.1101/2024.01.16.575849 — neuroscience — Posted on 2024-01-16

2355 Single dopaminergic neuron DAN-c1 in Drosophila larval brain mediates aversive olfactory learning through D2-like receptors

Qi, C.; Qian, C.; Steijvers, E.; Colvin, R. A.; Lee, D.

10.1101/2024.01.15.575767 — neuroscience — Posted on 2024-01-16

2356 Elucidation of neuronal activity in mouse models of TMJ injury by in vivo GCaMP Ca2+ imaging of intact trigeminal ganglion neurons

Son, H.; Shannonhouse, J.; zhang, y.; Gomez, R.; Chung, M.-K.; Kim, Y. S.

10.1101/2024.01.16.575919 — neuroscience — Posted on 2024-01-16

2357 Mouse Auditory Cortex Undergoes Asynchronous Maturation in the Right and Left Hemispheres

Oviedo, H. V.; Reid, A.; Neophytou, D.; Levy, R.

10.1101/2024.01.16.575905 — neuroscience — Posted on 2024-01-16

2358 Polydopamine Nanoparticles as Mimicking RPE Melanin for the Protection of Retinal Cells Against Blue Light-Induced Phototoxicity

Kwon, Y.-S.; Zheng, M.; Smirnov, A. I.; Han, Z.

10.1101/2024.01.15.575719 — pharmacology and toxicology — Posted on 2024-01-16

2359 Generative AI for Cardiac Organoid Florescence Generation

Kandula, A. K. R.; Phamornratanakun, T.; Gomez, A. H.; Bhoi, R.; El-Mokahal, M.; Feng, Y.; Yang, H.

10.1101/2024.01.15.575724 — bioengineering — Posted on 2024-01-16

2360 The transgenerational consequences of paternal social isolation and predation exposure in threespined sticklebacks

Hellmann, J.; Rogers, M.

10.1101/2024.01.16.575739 — animal behavior and cognition — Posted on 2024-01-16

2361 Prediction error determines how memories are organized in the brain: a study of Pavlovian fear extinction in rats

Kennedy, N. G. W.; Lee, J. C.; Killcross, S.; Westbrook, R. F.; Holmes, N. M.

10.1101/2024.01.16.575867 — animal behavior and cognition — Posted on 2024-01-16

2362 Integrating complexity in population modelling: from matrix to dynamic models using the jellyfish Carybdea marsupialis

Flores-Garcia, A.; Dobson, J. Y.; Fonfria, E. S.; Garcia-Garcia, D.; Bordehore, C.

10.1101/2024.01.15.575756 — ecology — Posted on 2024-01-16

2363 Heterodimerization of Endolysin Isoforms During Bacterial Infection by Staphylococcal Phage {varphi}2638A

Zinsli, L. V.; Sobieraj, A. M.; Ernst, P.; Meile, S.; Kilcher, S.; Iseli, C.; Keller, A.; Dreier, B.; Mittl, P. R. E.; Plueckthun, A.; Loessner, M. J.; Schmelcher, M.; Dunne, M.

10.1101/2024.01.16.575832 — molecular biology — Posted on 2024-01-16

2364 Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody

Johnson, N. V.; Wall, S.; Kramer, K.; Holt, C.; Periasamy, S.; Richardson, S.; Suryadevara, N.; Andreano, E.; Paciello, I.; Pierleoni, G.; Piccini, G.; Huang, Y.; Ge, P.; Allen, J.; Uno, N.; Shiakolas, A.; Pilewski, K.; Nargi, R.; Abu-Shmais, A.; Sutton, R.; Parks, R.; Haynes, B.; Carnahan, R.; Crowe, J.; Montomoli, E.; Rappuoli, R.; Bukreyev, A.; Ross, T.; Sautto, G.; Georgiev, I.; McLellan, J.

10.1101/2024.01.15.575741 — molecular biology — Posted on 2024-01-16

2365 Role of histone variants H2BC1 and H2AZ.2 in H2AK119ub nucleosome organization and Polycomb gene silencing

Shen, X.; Chen, C.; Wang, Y.; Zheng, W.; Zheng, J.; Jones, A.; Zhu, B.; Zhang, H.; Lyons, C.; Rijal, A.; Mobley, J.; Cao, G.; Liu, K.; Winn, R.; Dickinson, A. J. G.; Zhang, K.; Wang, H.

10.1101/2024.01.16.575234 — molecular biology — Posted on 2024-01-16

2366 The impact of struvite and ash recycling-derived fertilizers on microbial phosphorus mobilization capabilities and community structure in a Lolium perenne field trial

Deinert, L.; Ashekuzzaman, S. M.; Forrestal, P.; Schmalenberger, A.

10.1101/2024.01.16.575387 — microbiology — Posted on 2024-01-16

2367 HSV-1 ICP0 Dimer Domain Adopts a Novel β-barrel Fold

McCloskey, E.; Kashipathy, M.; Cooper, A.; Gao, P.; Johnson, D. K.; Battaile, K. P.; Lovell, S.; Davido, D.

10.1101/2024.01.16.575752 — microbiology — Posted on 2024-01-16

2368 Quantitative assessment of Newcastle disease virus proteins interactions with all known mucin types of Chicken and Quail

Almhanna, H.; Kumar, A. H.

10.1101/2024.01.16.575848 — microbiology — Posted on 2024-01-16

2369 Enhanced legumain activity links progranulin deficiency to TDP-43 pathology in frontotemporal lobar degeneration

Robinson, S.; Reich, M.; Muehlhofer, M.-T.; Buschmann, K.; Wauters, E.; Muehlhofer, Q.; Werner, G.; Ahles, A.; Engelhardt, S.; Krenner, C.; Bartels, B.; Gutbier, S.; Reifschneider, A.; Riemenschneider, H.; Reinheckel, T.; Edbauer, D.; Simon, M. J.; Kariolis, M. S.; Logan, T.; Di Paolo, G.; Van Broeckhoven, C.; Damme, M.; Paquet, D.; Haass, C.; Capell, A.

10.1101/2024.01.16.575687 — neuroscience — Posted on 2024-01-16

2370 A call for a unified and multimodal definition of cellular identity in the enteric nervous system

Majd, H.; Cesiulis, A.; Samuel, R. M.; Richter, M. N.; Elder, N.; Guyer, R. A.; Hao, M.; Stamp, L.; Goldstein, A.; Fattahi, F.

10.1101/2024.01.15.575794 — neuroscience — Posted on 2024-01-16

2371 Cerebral Blood Volume Modulates Glymphatic Influx Through Extra-ventricular Cerebrospinal Fluid Volume

Li, J.; Liu, X.; Bo, B.; Pei, M.; Zhang, K.; Tong, C.; Jiang, M.; Zhang, S.; Li, Y.; Cang, J.; Liang, Z.; Fang, F.

10.1101/2024.01.15.575561 — neuroscience — Posted on 2024-01-16

2372 An intracranial dissection of human escape circuits

Zhang, H.; Cheng, J.; Hu, K.; Wang, F.; Qi, S.; Liu, Q.; Yao, Y.; Mobbs, D.; Wu, H.

10.1101/2024.01.16.575785 — neuroscience — Posted on 2024-01-16

2373 Host brain environmental influences on transplanted medial ganglionic eminence progenitors

Paterno, R.; Vu, T.; Hsieh, C.; Baraban, S. C.

10.1101/2024.01.15.575686 — neuroscience — Posted on 2024-01-16

2374 Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis

Ionescu, R.-B.; Nicaise, A. M.; Reisz, J. A.; Williams, E. C.; Prasad, P.; Dzieciatkowska, M.; Stephenson, D.; Suarez Cubero, M.; Pirvan, L.; Willis, C. M.; Peruzzotti-Jametti, L.; Fossati, V.; Edenhofer, F.; Leonardi, t.; Frezza, C.; Mohorianu, I.; D'Alessandro, A.; Pluchino, S.

10.1101/2024.01.16.575826 — neuroscience — Posted on 2024-01-16

2375 An Incremental Large Language Model for long text processing in the Brain

Tikochinski, R.; Goldstein, A.; Meiri, Y.; Hasson, U.; Reichart, R.

10.1101/2024.01.15.575798 — neuroscience — Posted on 2024-01-16

2376 Synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse prefrontal cortex

Fekete, Z.; Weisz, F.; Karlocai, R.; Veres, J.; Andrasi, T.; Hajos, N.

10.1101/2024.01.16.575904 — neuroscience — Posted on 2024-01-16

2377 Segmentation-free measurement of locomotor frequency in Caenorhabditis elegans using image invariants

Ji, H.; Chen, D.; Fang-Yen, C.

10.1101/2024.01.16.575892 — neuroscience — Posted on 2024-01-16

2378 Rapid learning of temporal dependencies at multiple timescales

Smith, C. M.; Thompson-Schill, S. L.; Schapiro, A. C.

10.1101/2024.01.15.575748 — neuroscience — Posted on 2024-01-16

2379 Sex-specific mechanisms underlie long-term potentiation at hippocampus-nucleus accumbens synapses

Copenhaver, A. E.; LeGates, T. A.

10.1101/2024.01.15.575709 — neuroscience — Posted on 2024-01-16

2380 General mechanisms of task engagement in the primate frontal cortex

Grohn, J.; Khalighinejad, N.; Jahn, C.; Bongioanni, A.; Schuffelgen, U.; Sallet, J.; Rushworth, M.; Kolling, N.

10.1101/2024.01.16.575830 — neuroscience — Posted on 2024-01-16

2381 Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and TGFβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis

Chen, W.; Lu, Y.; Zhang, Y.; Wu, J.; McVicar, A.; Chen, Y.; Zhu, S.; Zhu, G.; Lu, Y.; Zhang, J.; McConnell, M.; Li, Y.-P.

10.1101/2024.01.15.575763 — pathology — Posted on 2024-01-16

2382 Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes

Patel, D.; Tiusanen, V.; Pihlajamaa, P.; Sahu, B.

10.1101/2024.01.15.575744 — cancer biology — Posted on 2024-01-16

2383 An Integrated Machine Learning Approach Delineates Entropic Modulation of alpha-Synuclein by Small Molecule

Menon, S.; Adhikari, S.; Mondal, J.

10.1101/2024.01.15.575555 — biophysics — Posted on 2024-01-16

2384 Adsorption-driven deformation and landing-footprints of the RBD proteins in SARS-CoV-2 variants onto biological and inanimate surfaces

Bosch, A.; V. Guzman, H.; Perez, R.

10.1101/2024.01.15.575706 — biophysics — Posted on 2024-01-16

2385 Dynamically driven correlations in elastic net models reveal sequence of events and causality in proteins

Erkip, A.; Erman, B.

10.1101/2024.01.15.575718 — bioinformatics — Posted on 2024-01-16

2386 GEMCAT - A new algorithm for gene expression-based prediction of metabolic alterations

Sharma, S.; Sauter, R.; Hotze, M.; Prowatke, A. M. P.; Niere, M.; Kipura, T.; Egger, A.-S.; Thedieck, K.; Kwiatkowski, M.; Ziegler, M.; Heiland, I.

10.1101/2024.01.15.575710 — bioinformatics — Posted on 2024-01-16

2387 Immunoinformatic approach to design CTL epitope based chimeric vaccine targeting multiple serotypes of dengue virus

Manocha, N.; Kumar, P.; Khanna, M.

10.1101/2024.01.15.575641 — bioinformatics — Posted on 2024-01-16

2388 The blobulator: a webtool for identification andvisual exploration of hydrophobic modularity inprotein sequences

Pitman, C.; Santiago-McRae, E.; Lohia, R.; Bassi, K.; Joseph, T. T.; Hansen, M. E. B.; Brannigan, G.

10.1101/2024.01.15.575761 — bioinformatics — Posted on 2024-01-16

2389 A Distributed Computing Solution for Privacy-Preserving Genome-Wide Association Studies

Brito, C.; Paulo, J.; Ferreira, P. G.

10.1101/2024.01.15.575678 — bioinformatics — Posted on 2024-01-16

2390 AnnoView enables large-scale analysis, comparison, and visualization of microbial gene neighborhoods

Wei, X.; Tan, H.; Lobb, B.; Zhen, W.; Wu, Z.; Parks, D. H.; Neufeld, J. D.; Moreno-Hagelsieb, G.; Doxey, A. C.

10.1101/2024.01.15.575735 — bioinformatics — Posted on 2024-01-16

2391 A Wireless Wearable Ecosystem for Social Network Analysis in Free-living Animals

Gaidica, M.; Zhang, M.; Dantzer, B.

10.1101/2024.01.15.575769 — animal behavior and cognition — Posted on 2024-01-16

2392 Noxious stimulation induces self-protective behaviour in bumblebees

Gibbons, M.; Pasquini, E.; Kowalewska, A.; Read, E.; Gibson, S.; Crump, A.; Solvi, C.; Versace, E.; Chittka, L.

10.1101/2024.01.15.575734 — animal behavior and cognition — Posted on 2024-01-16

2393 Decline of honeybees and its consequences for beekeepers and crop pollination in western Nepal

Kortsch, S.; Timberlake, T. P.; Cirtwill, A.; Sapkota, S.; Devkota, K.; Roslin, T.; Memmott, J.; Saville, N.

10.1101/2024.01.15.575723 — ecology — Posted on 2024-01-16

2394 An essential mechanosensitive channel Pkd2 modulates the assembly of type II myosin and actin filaments in the cytokinetic contractile ring

Chowdhury, P.; Sinha, D.; Poddar, A.; Chetluru, M.; Chen, Q.

10.1101/2024.01.15.575753 — cell biology — Posted on 2024-01-16

2395 Domain-general cognitive control processes in bilingual switching: evidence from midfrontal theta oscillations

Cui, N.; Piai, V.; Zheng, X. Y.

10.1101/2024.01.15.575665 — neuroscience — Posted on 2024-01-16

2396 Dynamical models reveal anatomically reliable attractor landscapes embedded in resting state brain networks

Chen, R.; Singh, M. F.; Braver, T. S.; Ching, S.

10.1101/2024.01.15.575745 — neuroscience — Posted on 2024-01-16

2397 Rapid dynamics of electrophysiological connectome states are heritable

Jun, S.; Malone, S.; Iacono, W. G.; Wilson, S.; Sadaghiani, S.; Harper, J.

10.1101/2024.01.15.575731 — neuroscience — Posted on 2024-01-16

2398 The long distance relationship of regional amyloid burden and tau pathology spread

Hoenig, M.; Doering, E.; Bischof, G.; Drzezga, A.; van Eimeren, T.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/2024.01.15.575698 — neuroscience — Posted on 2024-01-16

2399 Opioid-driven disruption of the septal complex reveals a role for neurotensin- expressing neurons in withdrawal

Simon, R.; Fleming, W.; Senthilkumar, P.; Briones, B.; Ishii, K.; Hjort, M.; Martin, M.; Hashikawa, K.; Sanders, A.; Golden, S.; Stuber, G.

10.1101/2024.01.15.575766 — neuroscience — Posted on 2024-01-16

2400 Three-dimensional morphology of the vibrissal array of the harbor seal (Phoca vitulina)

Graff, M. M.; Belli, H. M.; Wieskotten, S.; Krüger, Y.; Dehnhardt, G.; Hartmann, M. J. Z.

10.1101/2024.01.15.575743 — neuroscience — Posted on 2024-01-16

2401 Automating the Human Connectome Project's Temporal ICA Pipeline

Yang, C.; Coalson, T. S.; Smith, S. M.; Elam, J. S.; Van Essen, D. C.; Glasser, M. F.

10.1101/2024.01.15.574667 — neuroscience — Posted on 2024-01-16

2402 Astrocytic CREB in nucleus accumbens promotes susceptibility to chronic stress

Holt, L. M.; Gyles, T. M.; Parise, E. M.; Minier-Toribio, A.; Markovic, T.; Rivera, M.; Yeh, S.-Y.; Nestler, E. J.

10.1101/2024.01.15.575728 — neuroscience — Posted on 2024-01-16

2403 p75NTR upregulation following perinatal hypoxia leads to deficits in parvalbumin-expressing GABAergic cell maturation, cortical activity and cognitive abilities in adult mice

Chattopadhyaya, B.; Lee, K. K. Y.; Carreno-Munoz, M. I.; Paris-Rubianes, A.; Lavertu-Jolin, M.; Berryer, M. H.; Longo, F. M.; Di Cristo, G.

10.1101/2024.01.16.574659 — neuroscience — Posted on 2024-01-16

2404 Alcohol Sipping Patterns, Personality, and Psychopathology in Children: Moderating Effects of Dorsal Anterior Cingulate Cortex (dACC)

Ferariu, A.; Taylor, A.; Chang, H.; Zhang, F.

10.1101/2024.01.15.575762 — neuroscience — Posted on 2024-01-16

2405 Leveraging Multi-echo EPI to Enhance BOLD Sensitivity in Task-based Olfactory fMRI

Zhao, L. S.; Raithel, C. U.; Tisdall, D.; Detre, J. A.; Gottfried, J. A.

10.1101/2024.01.15.575530 — neuroscience — Posted on 2024-01-16

2406 Cognitive abilities are associated with rapid dynamics of electrophysiological connectome states

Jun, S.; Malone, S. M.; Iacono, W. G.; Harper, J.; Wilson, S.; Sadaghiani, S.

10.1101/2024.01.15.575736 — neuroscience — Posted on 2024-01-16

2407 Neural Dynamics and Seizure Correlations: Insights from Neural Mass Models in a Tetanus Toxin Rat Model of Epilepsy

Zarei Eskikand, P.; Soto-Breceda, A.; Cook, M. J.; Burkitt, A. N.; Grayden, D. B.

10.1101/2024.01.15.575784 — neuroscience — Posted on 2024-01-16

2408 Few-shot pattern detection by transient boosting of somato-dendritic coupling

Sivori, G.; Fukai, T.

10.1101/2024.01.16.575776 — neuroscience — Posted on 2024-01-16

2409 Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

Burban, A.; Tessier, C.; Pinglaut, M.; Guyon, J.; Galvis, J.; Dartigues, B.; Toujas, M.; Larroquette, M.; Luchman, H. A.; Weiss, S.; Nicot, N.; Klink, B.; Nikolski, M.; Brisson, L.; Mathivet, T.; Bikfalvi, A.; Daubon, T.; Sharanek, A.

10.1101/2024.01.15.574967 — cancer biology — Posted on 2024-01-16

2410 When the pen is mightier than the sword: semi-automatic 2 and 3D image labelling

Hollandi, R.; Bauer, D.; Diosdi, A.; Schrettner, B.; Toth, T.; Hirling, D.; Hollandi, G.; Harmati, M.; Molnar, J.; Horvath, P.

10.1101/2024.01.15.575658 — bioinformatics — Posted on 2024-01-16

2411 The threshold for intracranial self-stimulation does not increase in rats exposed to chronic unpredictable stress, a systematic review and meta-analysis

Berrio, J.; Wilzopolski, J.; Hohlbaum, K.; Kalliokoski, O.

10.1101/2024.01.15.575675 — animal behavior and cognition — Posted on 2024-01-16

2412 Applying gradient tree boosting to QTL mapping with Shapley additive explanations

Ishibashi, T.; Onogi, A.

10.1101/2024.01.15.575690 — genetics — Posted on 2024-01-16

2413 Origin and evolutionary trajectories of brown algal sex chromosomes

Barrera-Redondo, J.; Lipinska, A. P.; Liu, P.; Dinatale, E.; Cossard, G.; Bogaert, K.; Hoshino, M.; Avia, K.; Avdievich, E.; Leiria, G.; Liesner, D.; Luthringer, R.; Godfroy, O.; Heesch, S.; Nehr, Z.; Peters, A. F.; Hoarau, G.; Pearson, G. A.; Aury, J.-M.; Wincker, P.; Denoeud, F.; Cock, J. M.; Haas, F. B.; Coelho, S. M.

10.1101/2024.01.15.575685 — evolutionary biology — Posted on 2024-01-16

2414 Myocardial B cells have specific gene expression and predicted interactions in Dilated Cardiomyopathy and Arrhythmogenic Right Ventricular Cardiomyopathy

Bermea, K. C.; Duque, C.; Cohen, C. D.; Bhalodia, A.; Rousseau, S.; Lovell, J.; Zita, M. D.; Mugnier, M. C.; Adamo, L.

10.1101/2023.09.21.558902 — immunology — Posted on 2024-01-16

2415 The preoptic Kisspeptin/nNOS/GnRH (KiNG) neuronal network regulates rhythmic LH release through a dual activation-inhibition mechanism

Delli, V.; Seux, C.-A.; Dehame, J.; Nair, S.; Lhomme, T.; CHACHLAKI, K.

10.1101/2024.01.15.575688 — neuroscience — Posted on 2024-01-16

2416 A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

Patel, A. G.; Ashenberg, O.; Collins, N. B.; Segerstolpe, A.; Jiang, S.; Slyper, M.; Huang, X.; Caraccio, C.; Jin, H.; Sheppard, H.; Xu, K.; Chang, T.-C.; Orr, B. A.; Shirinifard, A.; Chapple, R. H.; Shen, A.; Clay, M. R.; Tatevossian, R. G.; Reilly, C.; Patel, J.; Lupo, M.; Cline, C.; Dionne, D.; Porter, C. B. M.; Waldman, J.; Bai, Y.; Zhu, B.; Barrera, I.; Murray, E.; Vigneau, S.; Napolitano, S.; Wakiro, I.; Wu, J.; Grimaldi, G.; Dellostritto, L.; Helvie, K.; Rotem, A.; Lako, A.; Cullen, N.; Pfaff, K. L.; Karlstrom, A.; Jane-Valbuena, J.; Todres, E.; Thorner, A.; Geeleher, P.; Rodig, S. J.;

10.1101/2024.01.07.574538 — cancer biology — Posted on 2024-01-16

2417 vcfpp: a C++ API for rapid processing of the Variant Call Format

Li, Z.

10.1101/2023.10.12.555914 — bioinformatics — Posted on 2024-01-16

2418 WITHDRAWN: BBB recovery after stroke by self-replenishing E-pericytes transdifferentiated from local endothelial cells.

Li, T.-B.; Jia, J.-M.; Tu, J.-Q.; Gao, Q.-Z.; Zhu, Z.; Li, X.-Z.; Jin, Y.-X.; Zhang, Y.-Y.; Xie, J.-F.; Zhu, P.-R.; Zhao, B.-R.

10.1101/2024.01.07.573171 — molecular biology — Posted on 2024-01-16

2419 Reference materials for SARS-CoV-2 molecular diagnostic quality control: validation of encapsulated synthetic RNAs for room temperature storage and shipping

Colotte, M.; Luis, A.; Coudy, D.; Tuffet, S.; Robene, I.; Fenelon, B.; Jouen, E.; Leveque, N.; Deroche, L.; Alain, S.; Plumelle, D.; Tumiotto, C.; Busson, L.; Lafon, M.-E.; Bonnet, J.

10.1101/2023.08.28.555008 — molecular biology — Posted on 2024-01-16

2420 Caveolin scaffolding domain (CSD) peptide LTI-2355 modulates the phagocytic and synthetic activity of lung derived myeloid cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-acute sequelae of COVID-fibrosis (PASC-F)

Creyns, B.; MacKenzie, B.; Sa, Y.; Coelho, A. L.; Christensen, D.; Parimon, T.; Windsor, B.; Hogaboam, C. M.

10.1101/2023.12.01.569608 — immunology — Posted on 2024-01-16

2421 Neuromodulation via muscarinic acetylcholine pathway can facilitate distinct, complementary, and sequential roles for NREM and REM states during sleep-dependent memory consolidation

Satchell, M.; Fry, B.; Noureddine, Z.; Simmons, A.; Ognjanovski, N.; Aton, S.; Zochowski, M.

10.1101/2023.05.19.541465 — neuroscience — Posted on 2024-01-16

2422 The relationship between white matter architecture and language lateralisation in the healthy brain

Andrulyte, I.; de Bezenac, C.; Branzi, F.; Forkel, S. J.; Taylor, P. N.; Keller, S. S.

10.1101/2024.01.12.572159 — neuroscience — Posted on 2024-01-16

2423 Demystifying the Visual Word Form Area: Visual and Nonvisual Response Properties of Ventral Temporal Cortex with precision fMRI

Li, J.; Hiersche, K.; Saygin, Z. M.

10.1101/2023.06.15.544824 — neuroscience — Posted on 2024-01-16

2424 A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development

Courtney, Y.; Head, J. P.; Yimer, E. D.; Dani, N.; Shipley, F. B.; Libermann, T. A.; Lehtinen, M. K.

10.1101/2024.01.08.574486 — neuroscience — Posted on 2024-01-16

2425 Compact RNA sensors for increasingly complex functions of multiple inputs

Choe, C. A.; Andreasson, J. O. L.; Melaine, F.; Kladwang, W.; Wu, M. J.; Portela, F.; Wellington-Oguri, R.; Nicol, J. J.; Wayment-Steele, H. K.; Gotrik, M.; Eterna Participants (Eterna Massive Open Laboratory), ; Khatri, P.; Greenleaf, W. J.; Das, R.

10.1101/2024.01.04.572289 — synthetic biology — Posted on 2024-01-16

2426 TRPM8-dependent shaking in mammals and birds

Selescu, T.; Bivoleanu, R.-A.; Iodi Carstens, M.; Manolache, A.; Caragea, V.-M.; Hutanu, D.-E.; Meerupally, R.; Wei, E. T.; Carstens, E.; Zimmermann, K.; Babes, A.

10.1101/2023.12.27.573364 — physiology — Posted on 2024-01-16

2427 ANDROMEDA by Prosilico and log D outperform human hepatocytes for the prediction of intrinsic hepatic metabolic clearance of carboxylic acids

Fagerholm, U.

10.1101/2023.12.04.569912 — pharmacology and toxicology — Posted on 2024-01-16

2428 The everting Drosophila wing disc is a shape-programmed material

Fuhrmann, J. F.; Krishna, A.; Paijmans, J.; Duclut, C. A.; Eaton, S.; Popovic, M.; Julicher, F.; Modes, C. D.; Dye, N. A.

10.1101/2023.12.23.573034 — biophysics — Posted on 2024-01-16

2429 Integrated platform for multi-scale molecular imaging and phenotyping of the human brain

Park, J.; Wang, J.; Guan, W.; Gjesteby, L. A.; Pollack, D.; Kamentsky, L.; Evans, N. B.; Stirman, J.; Gu, X.; Zhao, C.; Marx, S.; Kim, M. E.; Choi, S. W.; Snyder, M.; Chavez, D.; Su-Arcaro, C.; Tian, Y.; Park, C. S.; Zhang, Q.; Yun, D. H.; Moukheiber, M.; Feng, G.; Yang, X. W.; Keene, C. D.; Hof, P. R.; Ghosh, S. S.; Frosh, M. P.; Brattain, L. J.; Chung, K.

10.1101/2022.03.13.484171 — bioengineering — Posted on 2024-01-16

2430 Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England

Yu, Q.; Ascensao, J. A.; Okada, T.; The COVID-19 Genomics UK (COG-UK) consortium, ; Boyd, O.; Volz, E.; Hallatschek, O.

10.1101/2022.11.21.517390 — evolutionary biology — Posted on 2024-01-16

2431 The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals

Phillips, J. E.; Pan, D.

10.1101/2023.07.25.550562 — cell biology — Posted on 2024-01-16

2432 Immune Response following FLASH and Conventional Radiation in Diffuse Midline Glioma (DMG)

Padilla, O.; Minns, H. E.; Wei, H.-J.; Fan, W.; Webster-Carrion, A.; Tazhibi, M.; McQuillan, N. M.; Zhang, X.; Gallitto, M.; Yeh, R.; Zhang, Z.; Hei, T. K.; Szalontay, L.; Pavisic, J.; Tan, Y.; Deoli, N. R.; Garty, G.; Garvin, J. H.; Canoll, P. D.; Vanpouille-Box, C.; Menon, V.; Olah, M.; Wu, C.-C.; Rabadan, R.; Gartrell, R. D.

10.1101/2022.11.09.515507 — immunology — Posted on 2024-01-16

2433 Self-supervised learning to predict intrahepatic cholangiocarcinoma transcriptomic classes on routine histology

Beaufrere, A.; Lazard, T.; Nicolle, R.; Lubuela, G.; Augustin, J.; Albuquerque, M.; Pichon, B.; Pignolet, C.; Priori, V.; Theou-Anton, N.; Lesurtel, M.; Bouattour, M.; Mondet, K.; Cros, J.; Calderaro, J.; Walter, T.; Paradis, V.

10.1101/2024.01.15.575652 — cancer biology — Posted on 2024-01-16

2434 ROR2 regulates cellular plasticity in pancreatic neoplasia and adenocarcinoma

Benitz, S.; Steep, A.; Nasser, M.; Preall, J.; Mahajan, U. M.; McQuithey, H.; Loveless, I.; Davis, E. T.; Wen, H.-J.; Long, D. W.; Metzler, T.; Zwernik, S.; Louw, M.; Rempinski, D.; Salas-Escabillas, D.; Brender, S.; Song, L.; Huang, L.; Zhang, Z.; Steele, N. G.; Regel, I.; Bednar, F.; Crawford, H. C.

10.1101/2023.12.13.571566 — cancer biology — Posted on 2024-01-16

2435 The molecular basis for the increased stability of the FUS-LC fibril at the anionic membrane- and air-water interfaces

Paul, S.; Mondal, S.; Shenogina, I.; Cui, Q.

10.1101/2024.01.15.575617 — biophysics — Posted on 2024-01-16

2436 A rigorous benchmarking of alignment-based HLA callers for RNA-seq data

Yu, D.; Ayyala, R.; Sadek, S. H.; Chittampalli, L.; Farooq, H.; Jung, J.; Nahid, A. A.; Boldirev, G.; Jung, M.; Park, S.; Nguyen, A. D.; Zelikovsky, A.; Joo, J. W.; Thompson, R. F.; Alachkar, H.; Mancuso, N.; Mangul, S.

10.1101/2023.05.22.541750 — bioinformatics — Posted on 2024-01-16

2437 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting

Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.

10.1101/2022.06.23.497372 — bioengineering — Posted on 2024-01-16

2438 Comparative pangenome analysis of major pneumococcal genotypes from India

Peela, S. C. M.; Sistla, S.

10.1101/2024.01.14.575557 — genomics — Posted on 2024-01-16

2439 Risk assessment during nest defense against three simulated predators by northern house wrens (Troglodytes aedon aedon)

Eggleston, R. C.; Fornara, J. H.; Davis, K. M.; Dong, J.; Reichard, D. G.

10.1101/2023.02.01.526454 — evolutionary biology — Posted on 2024-01-16

2440 An open-source, high resolution, automated fluorescence microscope

Zehrer, A. C.; Martin-Villalba, A.; Diederich, B.; Ewers, H.

10.1101/2023.05.31.542706 — cell biology — Posted on 2024-01-16

2441 Phosphorylation-controlled cohesion of a nuclear condensate regulates mRNA retention

McIntyre, A. B. R.; Tschan, A.; Meyer, K.; Walser, S.; Rai, A. K.; Fujita, K.; Pelkmans, L.

10.1101/2023.08.21.554101 — cell biology — Posted on 2024-01-16

2442 A treasure trove of 1,034 actinomycete genomes

Jorgensen, T. S.; Mohite, O.; Sterndorff, E. B.; Alvarez-Arevalo, M.; Blin, K.; Booth, T. J.; Charusanti, P.; Faurdal, D.; Hansen, T. O.; Nuhamunada, M. J.; Mourched, A.-S.; Palsson, B. O.; Weber, T.

10.1101/2024.01.16.574955 — microbiology — Posted on 2024-01-16

2443 Three components of human brain gene expression reflect normative developmental programmes with specific links to neurodevelopmental disorders

Dear, R.; Wagstyl, K.; Seidlitz, J.; Markello, R. D.; Arnatkeviciute, A.; Anderson, K. M.; Bethlehem, R. A. I.; Lifespan Brain Chart Consortium, ; Raznahan, A.; Bullmore, E. T.; Vertes, P.

10.1101/2022.10.05.510582 — neuroscience — Posted on 2024-01-16

2444 Altered hierarchical auditory predictive processing after lesions to the orbitofrontal cortex

Asko, O.; Blenkmann, A. O.; Leske, S. L.; Foldal, M. D.; Llorens, A.; Funderud, I.; Meling, T. R.; Knight, R. T.; Endestad, T.; Solbakk, A.-K.

10.1101/2023.01.04.521570 — neuroscience — Posted on 2024-01-16

2445 KaMRaT: a C++ toolkit for k-mer count matrix dimension reduction

Xue, H.; Gallopin, M.; Marchet, C.; Nguyen, T. N. H.; Wang, Y.; Bessiere, C.; Gautheret, D.

10.1101/2024.01.15.575511 — bioinformatics — Posted on 2024-01-16

2446 Genomic epidemiology of Candida auris introduction and outbreaks in the United Kingdom

Kappel, D.; Gifford, H.; Brackin, A. P.; Abdolrasouli, A.; Eyre, D. W.; Jeffery, K.; Schelenz, S.; Aanensen, D.; Brown, C.; Borman, A.; Johnson, E.; Holmes, A.; Armstrong-James, D.; Fisher, M.; Rhodes, J.

10.1101/2024.01.15.575049 — genomics — Posted on 2024-01-16

2447 Natural diversity of heat-induced transcription of retrotransposons in Arabidopsis thaliana

Xu, W.; Thieme, M.; Roulin, A.

10.1101/2024.01.15.575637 — genomics — Posted on 2024-01-16

2448 Creation and Validation of the First Infinium DNA Methylation Array for the Human Imprintome

Carreras-Gallo, N.; Dwaraka, V. B.; Jima, D. D.; Skaar, D. A.; Mendez, T. L.; Planchart, A.; Zhou, W.; Jirtle, R. L.; Smith, R.; Hoyo, C.

10.1101/2024.01.15.575646 — genetics — Posted on 2024-01-16

2449 NRV: An open framework for in silico evaluation of peripheral nerve electrical stimulation strategies

Kolbl, F.; Couppey, T.; Regnacq, L.; Giraud, R.; Bornat, Y.; Romain, O.

10.1101/2024.01.15.575628 — neuroscience — Posted on 2024-01-16

2450 High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan

Gao, A. W.; El Alam, G. W.; Zhu, Y.; Li, W.; Katsyuba, E.; Sulc, J.; Li, T.; Li, X.; Overmyer, K. A.; Lalou, A.; Mouchiroud, L.; Bou Sleiman, M.; Cornaglia, M.; Morel, J.-D.; Houtkooper, R.; Coon, J.; Auwerx, J.

10.1101/2024.01.15.575638 — systems biology — Posted on 2024-01-16

2451 Circadian regulation of CaV1.2 expression by RORalpha in the mouse heart

Personnic, E.; Gerard, G.; Poilbout, C.; Jetten, A. M.; Gomez, A. M.; Benitah, J.-P.; Perrier, R.

10.1101/2024.01.15.575657 — physiology — Posted on 2024-01-16

2452 Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact.

Piekniewska, A.; Anderson, N.; Roelandse, M.; Lloyd, K.; Korf, I.; Voss, S. R.; de Castro, G.; Magnani, D.; Varga, Z.; James-Zorn, C.; Horb, M.; Grethe, J. S.; Bandrowski, A. E.

10.1101/2024.01.15.575636 — bioinformatics — Posted on 2024-01-16

2453 Impact of Unc-51 Like Kinase 4 (ULK4) on the Reactivity of the Extended Reward System in Response to Conditioned Stimuli

Treutlein, J.; Loehlein, S.; Einenkel, K. E.; Diekhof, E. K.; Gruber, O.

10.1101/2024.01.15.575326 — genetics — Posted on 2024-01-16

2454 Inflamed Natural Killer cells with adhesion defects are associated with a poor prognosis in Multiple Myeloma

Blanquart, E.; Ekren, R.; Rigaud, B.; Joubert, M.-V.; Daunes, H.; Cuisinier, M.; Villard, M.; Carrie, N.; Mazzotti, C.; Baylot, V.; Lucca, L. E.; Perrot, A.; Corre, J.; Walzer, T.; Avet-Loiseau, H.; Axisa, P.-P.; Martinet, L.

10.1101/2024.01.15.575654 — immunology — Posted on 2024-01-16

2455 Structural and sequential regularities modulate phrase-rate neural tracking

Zhao, J.; Martin, A. E.; Coopmans, C. W.

10.1101/2024.01.15.575585 — neuroscience — Posted on 2024-01-16

2456 Bidirectional fear modulation by discrete anterior insular circuits in mice

Park, S.; Huh, Y.; Kim, J. J.; Cho, J.

10.1101/2024.01.15.575700 — neuroscience — Posted on 2024-01-16

2457 Transcriptome Analysis Identifies An ASD-Like Phenotype In Oligodendrocytes And Microglia From C58/J Amygdala That Is Dependent On Sex and Sociability

Dalton, G. D.; Siecinski, S. K.; Nikolova, V. D.; Cofer, G. P.; Hornburg, K.; Qi, Y.; Johnson, G. A.; Jiang, Y.-H.; Moy, S. S.; Gregory, S. G.

10.1101/2024.01.15.575733 — neuroscience — Posted on 2024-01-16

2458 Invariant Neural Representation of Parts of Speech in the Human Brain

Misra, P.; Shih, Y.-C.; Yu, H.-Y.; Weisholtz, D.; Madsen, J. R.; Sceillig, S.; Kreiman, G.

10.1101/2024.01.15.575788 — neuroscience — Posted on 2024-01-16

2459 Long-horizon associative learning explains human sensitivity to statistical and network structures in auditory sequences

Benjamin, L.; Sable-Meyer, M.; Flo, A.; Dehaene-Lambertz, G.; Al Roumi, F.

10.1101/2024.01.16.575814 — neuroscience — Posted on 2024-01-16

2460 Translational validation of shotgun proteomics findings in cerebrospinal fluid of sporadic cerebral amyloid angiopathy patients

Vervuurt, M.; de Kort, A. M.; Kersten, I.; Rens, A. v.; Klijn, C. J. M.; Schreuder, F. H. B. M.; Lefeber, D.; Kuiperij, H. B.; Verbeek, M. M.

10.1101/2024.01.15.575618 — neuroscience — Posted on 2024-01-16

2461 Understanding functional brain reorganisation for naturalistic piano playing in novice pianists

Olszewska, A. M.; Gaca, M.; Drozdziel, D.; Widlarz, A.; Marchewka, A.; Herman, A. M.

10.1101/2024.01.15.575623 — neuroscience — Posted on 2024-01-16

2462 Personal Mastery Attenuates the Association between Greater Perceived Discrimination and Lower Amygdala and Anterior Hippocampal Volume in a Diverse Sample of Older Adults

Rosario, M.; Alotaibi, R.; Espinal-Martinez, A. O.; Ayoub, A.; Baumann, A.; Clark, U.; Cozier, Y.; Schon, K.

10.1101/2024.01.12.575447 — neuroscience — Posted on 2024-01-16

2463 Exploration of the EEG response to periodic thermal and vibrotactile stimuli

Courtin, A. S.; Mouraux, A.

10.1101/2024.01.15.575576 — neuroscience — Posted on 2024-01-16

2464 Leveraging Graph Machine Learning for Moonlighting Protein Prediction: A Local PPI Network and Physiochemical Feature Approach

Zhou, H.; Sarkar, R.

10.1101/2023.11.13.566879 — bioinformatics — Posted on 2024-01-16

2465 DORA: an interactive map for the visualization and analysis of ancient human DNA and associated data

Harris, K. D.; Greenbaum, G.

10.1101/2024.01.15.575663 — genomics — Posted on 2024-01-16

2466 Hypoxia impacts small intestinal organoid stemness and differentiation

Lan, X.; Qiu, P.; Mou, C.

10.1101/2023.12.30.573689 — cell biology — Posted on 2024-01-16

2467 A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels

Tadimari Prabhakar, A.; James, C. D.; Youssef, A. H.; Hossein, R. A.; Hill, R. D.; Bristol, M. L.; Dubey, A.; Wang, X.; Morgan, I. M.

10.1101/2024.01.15.575713 — molecular biology — Posted on 2024-01-16

2468 Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

Nabeel-Shah, S.; Pu, S.; Burke, G. L.; Ahmed, N.; Braunschweig, U.; Farhangmehr, S.; Lee, H.; Wu, M.; Ni, Z.; Tang, H.; Zhong, G.; Marcon, E.; Zhang, Z.; Blencowe, B. J.; Greenblatt, J. F.

10.1101/2024.01.15.575768 — molecular biology — Posted on 2024-01-16

2469 Global view of domain-specific O-linked mannose glycosylation in glycoengineered cells

Povolo, L.; Tian, W.; Vakhrushev, S. Y.; Halim, A.

10.1101/2024.01.15.575371 — molecular biology — Posted on 2024-01-16

2470 Spatiotemporal visualization of DNA replication by click chemistry reveals bubbling of viral DNA in virion formation

Gomez-Gonzalez, A.; Burkhardt, P.; Bauer, M.; Loehr, M. O.; Luedtke, N. W.; Greber, U. F.

10.1101/2024.01.16.575809 — microbiology — Posted on 2024-01-16

2471 ATP Prevents Aggregation of Protein via Modulating its Monomeric Conformation

Sarkar, S.; Gupta, S.; Mahato, C.; Das, D.; Mondal, J.

10.1101/2024.01.15.575740 — biochemistry — Posted on 2024-01-16

2472 Temporal and spatial dynamics within the fungal microbiome of grape fermentation

Onetto, C. A.; Ward, C. M.; Van Den Heuvel, S.; Hale, L.; Cuijvers, K.; Borneman, A.

10.1101/2024.01.15.574562 — microbiology — Posted on 2024-01-16

2473 Structural Basis of How MGME1 Processes DNA 5' Ends to Maintain Mitochondrial Genome Integrity

Mao, E. Y. C.; Yen, H.-Y.; Wu, C.-C.

10.1101/2024.01.15.575787 — biochemistry — Posted on 2024-01-16

2474 Multi-state kinetics of the syringe-like injection mechanism of Tc toxins

Ng`ang`a, P. N.; Folz, J.; Kucher, S.; Roderer, D.; Xu, Y.; Sitsel, O.; Belyy, A.; Prumbaum, D.; Kuehnemuth, R.; Assafa, T. E.; Dong, M.; Seidel, C. A. M.; Bordignon, E.; Raunser, S.

10.1101/2024.01.16.575634 — biochemistry — Posted on 2024-01-16

2475 Direct Measurement of 8OG syn-anti Flips in Mutagenic 8OG·A and Long-Range Damage-Dependent Hoogsteen Breathing Dynamics Using 1H CEST NMR

Gu, S.; Al-Hashimi, H. M.

10.1101/2024.01.15.575532 — biochemistry — Posted on 2024-01-16

2476 Requirements for the Biogenesis of Proteinsin the Human and Yeast Cytosol

Braymer, J. J.; Stehling, O.; Stuempfig, M.; Roesser, R.; Spantgar, F.; Blinn, C. M.; Muehlenhoff, U.; Pierik, A. J.; Lill, R.

10.1101/2024.01.15.575444 — biochemistry — Posted on 2024-01-16

2477 Biochemical and Structural Characterization of Fapy·dG Replication by Human DNA Polymerase β

Gao, S.; Oden, P. N.; Ryan, B. J.; Yang, H.; Freudenthal, B. D.; Greenberg, M. M.

10.1101/2024.01.15.575758 — biochemistry — Posted on 2024-01-16

2478 A treasure trove of 1,034 actinomycete genomes

Jorgensen, T. S.; Mohite, O.; Sterndorff, E. B.; Alvarez-Arevalo, M.; Blin, K.; Booth, T. J.; Charusanti, P.; Faurdal, D.; Hansen, T. O.; Nuhamunada, M. J.; Mourched, A.-S.; Palsson, B. O.; Weber, T.

10.1101/2024.01.16.574955 — microbiology — Posted on 2024-01-16

2479 Auranofin induces disulfide bond-mimicking S-Au-S bonds in protein thiol pairs

Quadros Barse, L.; Duchting, P.; Lupilov, N.; Bandow, J. E.; Kramer, U.; Leichert, L. I.

10.1101/2024.01.15.575694 — biochemistry — Posted on 2024-01-16

2480 Nitrous oxide respiration in acidophilic methanotrophs

Awala, S. I.; Gwak, J.-H.; Kim, Y.; Jung, M.-Y.; Dunfield, P. F.; Wagner, M.; Rhee, S.-K.

10.1101/2024.01.15.574570 — microbiology — Posted on 2024-01-16

2481 Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness

Amelink, J. S.; Postema, M. C.; Kong, X.-Z.; Schijven, D.; Carrion-Castillo, A.; Soheili-Nezhad, S.; Sha, Z.; Molz, B.; Joliot, M.; Fisher, S. E.; Francks, C.

10.1101/2023.11.22.568256 — genomics — Posted on 2024-01-16

2482 A centromere-derived retroelement RNA localizes in cis and is a core element of the transcriptional landscape of Drosophila centromeres

Santinello, B.; Sun, R.; Amjad, A.; Hoyt, S. J.; Ouyang, L.; Courret, C.; Drennan, R.; Leo, L.; Larracuente, A. M.; Core, L. M.; O'Neill, R. J.; Mellone, B. G.

10.1101/2024.01.14.574223 — cell biology — Posted on 2024-01-16

2483 Pan-cancer analysis of pyrimidine metabolism reveals signaling pathways connections with chemoresistance role

Ramesh, V.; Demirdizen, M.; Pinna, L.; Doktor, T. K.; Siddiqui, M. A.; Ceppi, P.

10.1101/2023.12.06.570388 — cancer biology — Posted on 2024-01-16

2484 How do stochastic processes and genetic threshold effects explain incomplete penetrance and inform causal disease mechanisms?

Jenkins, D.

10.1101/2023.10.04.560918 — genetics — Posted on 2024-01-16

2485 Single cell RNA-seq reveals protracted germ line X chromosome reactivation dynamics directed by a PRC2 dependent mechanism

Liu, Y.; Lau, X.; Munusamy, P.; Sanchez, C. A. S.; Snell, D.; Sangrithi, M.

10.1101/2023.11.06.565813 — developmental biology — Posted on 2024-01-16

2486 CD4 T cell contact drives macrophage cell cycle progression and susceptibility to lentiviral transduction

Mlcochova, P.; Heilig, R.; Fischer, R.; Gupta, R. K.

10.1101/2024.01.15.575666 — cell biology — Posted on 2024-01-16

2487 Changes in reward-induced neural activity upon Cafeteria Diet consumption

Heijkoop, R.; Lalanza, J. F.; Solanas, M.; Alvarez-Monell, A.; Subias-Gusils, A.; Escorihuela, R. M.; Snoeren, E. M.

10.1101/2023.10.20.563269 — neuroscience — Posted on 2024-01-16

2488 Stand age diversity affects forests resilience and stability, although unevenly

Vangi, E.; Dalmonech, D.; Cioccolo, E.; Marano, G.; Bianchini, L.; Puchi, P.; Grieco, E.; Cescatti, A.; Colantoni, A.; Chirici, G.; Collalti, A.

10.1101/2023.07.12.548709 — plant biology — Posted on 2024-01-16

2489 mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated non-degradative ubiquitination of eIF4A1

Jiao, D.; Sun, H.; Zhao, X.; Chen, Y.; Shi, Q.; Lv, Z.; Li, Y.; Wang, C.; Gao, K.

10.1101/2023.09.27.559872 — cancer biology — Posted on 2024-01-16

2490 Imaging analysis of six human histone H1 variants reveals universal enrichment of H1.2, H1.3, and H1.5 at the nuclear periphery and nucleolar H1X presence

Salinas-Pena, M.; Rebollo, E.; Jordan, A.

10.1101/2023.08.25.554769 — cell biology — Posted on 2024-01-16

2491 Impaired skeletal muscle regeneration induced by Cre recombinase activation in skeletal muscle stem cells

Kneppers, A.; Saugues, A.; Dabadie, C.; Ben Larbi, S.; Mounier, R.

10.1101/2024.01.15.575701 — cell biology — Posted on 2024-01-16

2492 Comparison and Evaluation of Neutralization of Clinically Frequently Used Antimicrobial Agents Using Three Different Culture Media in Simulated Blood Cultures

Hang, Y.; Xiong, J.; Hu, L.; Chen, Y.; Zou, S.; Fang, X.; Xiao, Y.; Cao, X.; Luo, H.; Li, X.; Liu, Y.; Zhong, Q.

10.1101/2024.01.15.575683 — microbiology — Posted on 2024-01-16

2493 Selective manipulation of the host RNA-polymerase transcription fidelity increases phenotypic mutations in an insect Parvovirus

Labadie, T.; Cambray, G.

10.1101/2024.01.15.575645 — microbiology — Posted on 2024-01-16

2494 Superiority of chromosomal compared to plasmid-encoded compensatory mutations

Wright, R. C. T.; Wood, J.; Bottery, M. J.; Muddiman, K. J.; Paterson, S.; Harrison, E.; Brockhurst, M. A.; Hall, J. P. J.

10.1101/2024.01.15.575717 — microbiology — Posted on 2024-01-16

2495 Variation in the response to antibiotics and life-history across the major Pseudomonas aeruginosa clone type (mPact) panel

Tueffers, L.; Batra, A.; Zimmermann, J.; Botelho, J.; Buchholz, F.; Liao, J.; Mendoza Mejia, N.; Munder, A.; Klockgether, J.; Tuemmler, B.; Rupp, J.; Schulenburg, H.

10.1101/2024.01.15.575732 — microbiology — Posted on 2024-01-16

2496 A new protocol for multispecies bacterial infections in zebrafish and their monitoring through automated image analysis

Schmitz, D. A.; Wechsler, T.; Li, H. B.; Menze, B.; Kuemmerli, R.

10.1101/2024.01.15.575759 — microbiology — Posted on 2024-01-16

2497 Pre-Columbian treponemes clarify worldwide spread of treponematosis

Gueyrard, M.; Pontarotti, P.; Drancourt, M.; Abi-Rached, L.

10.1101/2024.01.15.575648 — microbiology — Posted on 2024-01-16

2498 Gene editing of pigs to control influenza A virus infections

Kwon, T.; Artiaga, B.; McDowell, C. D.; Whitworth, K.; Wells, K.; Prather, R.; Delhon, G. A.; Cigan, M.; White, S.; Retallick, J.; Gaudreault, N. N.; Morozov, I.; Richt, J. A.

10.1101/2024.01.15.575771 — microbiology — Posted on 2024-01-16

2499 RECON gene disruption enhances host resistance to enable genome-wide evaluation of intracellular pathogen fitness during infection.

Stamm, C. E.; McFarland, A. P.; Locke, M. N.; Tabakh, H.; Tang, Q.; Thomason, M. K.; Woodward, J. J.

10.1101/2024.01.15.575726 — microbiology — Posted on 2024-01-16

2500 Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron

Martens, E.; Schaus, S. R.; Vasconcelos Pereira, G.; Luis, A. S.; Madlambayan, E.; Terrapon, N.; Ostrowski, M. P.; Jin, C.; Hansson, G. C.

10.1101/2024.01.15.575725 — microbiology — Posted on 2024-01-16

2501 Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinsons disease

Khan, S. S.; Jaimon, E.; Lin, Y.-E.; Nikoloff, J.; Tonelli, F.; Alessi, D. R.; Pfeffer, S. R.

10.1101/2024.01.15.575737 — neuroscience — Posted on 2024-01-16

2502 Non-Degenerate Two-Photon Imaging of Deep Rodent Cortex using Indocyanine Green in the water absorption window

Tomar, A.; Engelmann, S.; Woods, A. L.; Dunn, A. K.

10.1101/2024.01.13.575485 — neuroscience — Posted on 2024-01-16

2503 The Burden of Reliability: How Measurement Noise Limits Brain-Behaviour Predictions

Gell, M.; Eickhoff, S. B.; Omidvarnia, A.; Kueppers, V.; Patil, K. R.; Satterthwaite, T. D.; Mueller, V. I.; Langner, R.

10.1101/2023.02.09.527898 — neuroscience — Posted on 2024-01-16

2504 AnNoBrainer, an Automated Annotation of Mouse Brain Images using Deep Learning

Peter, R.; Hrobar, P.; Navratil, J.; Vagenknecht, M.; Soukup, J.; Tsuji, K.; Barrezueta, N. X.; Stoll, A. C.; Gentzel, R. C.; Sugam, J. A.; Marcus, J.; Bitton, D. A.

10.1101/2024.01.12.575415 — neuroscience — Posted on 2024-01-16

2505 Proteomic evidence of astrocytic dysfunction in the olfactory bulb of depressed suicides

Rahimian, R.; Perlman, K.; Fakhfouri, G.; Mpai, R.; Richard, V. R.; Hercher, C.; Penney, L.; Davoli, M. A.; Nagy, C.; Zahedi, R. P.; Borchers, C. H.; Giros, B.; Turecki, G.; Mechawar, N.

10.1101/2023.10.29.564604 — neuroscience — Posted on 2024-01-16

2506 Combining RASG12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold tumours hot

Anastasiou, P.; Moore, C.; Rana, S.; de Castro, A.; Tomaschko, M.; Boumelha, J.; Mugarza, E.; Blaj, C.; de Carne Trecesson, S.; Goldstone, R.; Smith, J.; Quintana, E.; Molina-Arcas, M.; Downward, J.

10.1101/2024.01.15.575765 — cancer biology — Posted on 2024-01-16

2507 High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

Andronico, L. A.; Jiang, Y.; Carannante, V.; Iskrak, S.; Sandoz, P. A.; Mikes, J.; Klymchenko, A. S.; Buggert, M.; Osterborg, A.; Onfelt, B.; Brodin, P.; Sezgin, E.

10.1101/2024.01.15.575649 — biophysics — Posted on 2024-01-16

2508 TemStaPro: protein thermostability prediction using sequence representations from protein language models

Pudziuvelyte, I.; Olechnovic, K.; Godliauskaite, E.; Sermokas, K.; Urbaitis, T.; Gasiunas, G.; Kazlauskas, D.

10.1101/2023.03.27.534365 — bioinformatics — Posted on 2024-01-16

2509 Hidden Markov Models based search in combination with structural bioinformatics pipeline leads to the identification of DAF-12 distant orthologous in Meloidogyne incognita

Schuster, C. D.; Zabala, V. J. S.; San Juan, R. B.; Sosa, E. J.; Rodriguez, C.; Kronberg, M. F.; Munarriz, E. R.; Burton, G.; Castro, O. A.; Modenutti, C. P.

10.1101/2023.07.19.549723 — bioinformatics — Posted on 2024-01-16

2510 scPharm: identifying pharmacological subpopulations of single cells for precision medicine in cancers

Tian, P.; Zheng, J.; Xu, Y.; Wu, T.; Chen, S.; Zhang, Y.; Zhang, B.; Qiao, K.; Fan, Y.; Ambrogio, C.; Wang, H.

10.1101/2023.12.11.571182 — bioinformatics — Posted on 2024-01-16

2511 A seven-sex species recognizes self and non-self mating-type via a novel protein complex

Yan, G.; Ma, Y.; Wang, Y.; Zhang, J.; Cheng, H.; Tan, F.; Wang, S.; Zhang, D.; Xiong, J.; Yin, P.; Miao, W.

10.1101/2023.11.08.566168 — genetics — Posted on 2024-01-16

2512 Genome-scale analysis of interactions between genetic perturbations and natural variation

Hale, J. J.; Matsui, T.; Goldstein, I.; Mullis, M.; Roy, K. R.; Ville, C. N.; Miller, D.; Wang, C.; Reynolds, T.; Steinmetz, L. M.; Levy, S. F.; Ehrenreich, I.

10.1101/2023.05.06.539663 — genetics — Posted on 2024-01-16

2513 The robustness of phylogenetic diversity indices to extinctions

Manson, K.

10.1101/2022.06.28.498028 — evolutionary biology — Posted on 2024-01-16

2514 Multifaceted effects of bycatch mitigation measures on target/non-target species for pelagic longline fisheries and consideration for bycatch management

Ochi, D.; Okamoto, K.; Ueno, S.

10.1101/2022.07.14.500149 — ecology — Posted on 2024-01-16

2515 A gene regulatory network for specification and morphogenesis of a Mauthner Cell homolog in non-vertebrate chordates

Kim, K.; Piekarz, K. M.; Stolfi, A.

10.1101/2024.01.15.575616 — developmental biology — Posted on 2024-01-16

2516 Sox9 links biliary maturation to branching morphogenesis

Hrncir, H. R.; Bombin, S.; Goodloe, B.; Hogan, C. B.; Jadi, O.; Gracz, A. D.

10.1101/2024.01.15.574730 — developmental biology — Posted on 2024-01-16

2517 A spatiotemporally resolved atlas of mRNA decay in the C. elegans embryo reveals differential regulation of mRNA stability across stages and cell types

Peng, F.; Nordgren, C. E.; Murray, J. I.

10.1101/2024.01.15.575757 — developmental biology — Posted on 2024-01-16

2518 A genetic and physiological model of renal dysfunction in Lowe syndrome

PADINJAT, R.; Ramesh, N. A.; Kataria, V.; Lama, I. S.; Thakur, R. S.; Ghosh, A.; Sharma, S.; Venugopal, A.; Vasudevan, A.

10.1101/2024.01.15.575703 — cell biology — Posted on 2024-01-16

2519 Senolytic Treatment for Low Back Pain.

Mannarino, M.; Cherif, H.; Ghazizadeh, S.; Martinez, O. W.; Sheng, K.; Cousineau, E.; Lee, S.; Stone, L. S.; Millecamps, M.; Gao, C.; Ouellet, J. A.; Haglund, L.

10.1101/2024.01.15.575738 — cell biology — Posted on 2024-01-16

2520 CD4 T cell contact drives macrophage cell cycle progression and susceptibility to lentiviral transduction

Mlcochova, P.; Heilig, R.; Fischer, R.; Gupta, R. K.

10.1101/2024.01.15.575666 — cell biology — Posted on 2024-01-16

2521 Targeting ductal-endothelial crosstalk alleviate pancreatitis

Gao, R.-r.; Ma, L.-y.; Chen, J.-w.; Wang, Y.-x.; Li, Y.-y.; Zhou, Z.-y.; Deng, Z.-h.; Zhong, J.; Shu, Y.-h.; Liu, Y.; Chen, Q.

10.1101/2024.01.15.575182 — cell biology — Posted on 2024-01-16

2522 Bacterial ADP-heptose initiates a revival stem cell program in the intestinal epithelium

Goyal, S.; Guo, C. X.; Ranger, A.; Tsang, D. K.; Singh, O.; Harrigan, C. F.; Zaslaver, O.; Rost, H.; Gaisano, H. Y.; Yuzwa, S.; Gao, N.; Wrana, J. L.; Philpott, D. J.; Gray-Owen, S. D.; Girardin, S.

10.1101/2024.01.15.575749 — cell biology — Posted on 2024-01-16

2523 Establishment of a novel amyotrophic lateral sclerosis patient-derived blood-brain barrier model: Investigating barrier dysfunction and immune cell interaction

Matsuo, K.; Nagata, K.; Umeda, R.; Shiota, T.; Morimoto, S.; Suzuki, N.; Aoki, M.; Okano, H.; Nakamori, M.; Nishihara, H.

10.1101/2024.01.15.575002 — cell biology — Posted on 2024-01-16

2524 Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

Horisberger, A.; Griffith, A.; Keegan, J.; Arazi, A.; Pulford, J.; Murzin, E.; Howard, K.; Hancock, B.; Fava, A.; Sasaki, T.; Ghosh, T.; Inamo, J.; Beuschel, R.; Cao, Y.; Preisinger, K.; Gutierrez-Arcelus, M.; Eisenhaure, T. M.; Guthridge, J.; Hoover, P. J.; Dall'Era, M.; Wofsy, D.; Kamen, D. L.; Kalunian, K. C.; Furie, R.; Belmont, M.; Izmirly, P.; Clancy, R.; Hildeman, D.; Woodle, E. S.; Apruzzese, W.; McMahon, M. A.; Grossman, J.; Barnas, J. L.; Payan-Schober, F.; Ishimori, M.; Weisman, M.; Kretzler, M.; Berthier, C. C.; Hodgin, J. B.; Demeke, D. S.; Putterman, C.; Accelerating Medicines Pa

10.1101/2024.01.14.575609 — immunology — Posted on 2024-01-16

2525 Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number

Manley, J.; Demas, J.; Kim, H.; Martinez Traub, F.; Vaziri, A.

10.1101/2024.01.15.575721 — neuroscience — Posted on 2024-01-16

2526 Projection-Targeted Photopharmacology Reveals Distinct Anxiolytic Roles for Presynaptic mGluR2 in Prefrontal- and Insula-Amygdala Synapses

Munguba, H.; Gutzeit, V. A.; Srivastava, I.; Kristt, M.; Singh, A.; Vijay, A.; Arefin, A.; Thukral, S.; Broichhagen, J.; Stujenske, J. M.; Liston, C.; Levitz, J.

10.1101/2024.01.15.575699 — neuroscience — Posted on 2024-01-16

2527 Gaze and Arrows: does the Gaze Following Patch in the posterior temporal cortex differentiate social and symbolic spatial cues?

Gorner, M.; Ramezanpour, H.; Dicke, P. W.; Thier, P.

10.1101/2024.01.15.575547 — neuroscience — Posted on 2024-01-16

2528 Investigating the validity and interpretability of longitudinal brain age underlying cognition in Asian children and older adults

Cheng, S. F.; Yue, W. L.; Ng, K. K.; Qian, X.; Liu, S.; Tan, T. W. K.; Nguyen, K.-N.; Leong, R. L. F.; Hilal, S.; Cheng, C.-Y.; Tan, A. P.; Law, E. C.; Gluckman, P. D.; Chen, C. L.-H.; Chong, Y. S.; Meaney, M. J.; Chee, M.; Yeo, B. T. T.; Zhou, J. H.

10.1101/2023.11.27.568184 — neuroscience — Posted on 2024-01-16

2529 Are molecular fingerprints useful when seeking diverse active drugs? (no)

Venkatraman, V.; Roy, A.; Demekas, D.; Gaiser, J.; Xiong, R.; Wheeler, T.

10.1101/2022.09.20.508800 — pharmacology and toxicology — Posted on 2024-01-16

2530 Single Cell Calcium profiling for the discrimination of cancer cell lines.

Caussette, C.; Bura, A.; Gueguinou, M.; Bellanger, D.; Robert, A.; Cancel, M.; Fromont-Hankard, G.; Vandier, C.; Maheo, K.; Brouard, T.; Crottes, D.

10.1101/2024.01.14.575608 — cancer biology — Posted on 2024-01-15

2531 DORA: an interactive map for the visualization and analysis of ancient human DNA and associated data

Harris, K. D.; Greenbaum, G.

10.1101/2024.01.15.575663 — genomics — Posted on 2024-01-16

2532 GABAB- GluK1 kainate receptor interplay modulates amygdala excitability and behavioral response to chronic stress

Ryazantseva, M.; Liiwand, M.; Lauri, S.

10.1101/2024.01.15.575620 — neuroscience — Posted on 2024-01-16

2533 Quantifying spectral information about source separation in multisource odour plumes

Tootoonian, S.; True, A. C.; Crimaldi, J. P.; Schaefer, A. T.

10.1101/2024.01.14.575605 — biophysics — Posted on 2024-01-15

2534 Nationwide surveillance identifies yellow fever and chikungunya viruses transmitted by various species of Aedes mosquitoes in Nigeria

Nwangwu, U.; Oguzie, J. U.; Nwachukwu, W. E.; Onwude, C. O.; Dogunro, F. A.; Diallo, M.; Ezihe, C. K.; Agashi, N. O.; Eloy, E. I.; Anokwu, S. O.; Anioke, C. C.; Ikechukwu, L. C.; Nwosu, C. M.; Nwaogo, O. N.; Ngwu, I. M.; Onyeanusi, R. N.; Okoronkwo, A. I.; Orizu, F. U.; Etiki, M. O.; Onuora, E. N.; Adeorike, S. T.; Okeke, P. C.; Chukwuekezie, O. C.; Ochu, J. C.; Ibrahim, S. S.; Ifedayo, A.; Ihekweazu, C.; Happi, C.

10.1101/2024.01.15.575625 — zoology — Posted on 2024-01-15

2535 OmniNA: A foundation model for nucleotide sequences

Shen, X.; Li, X.

10.1101/2024.01.14.575543 — bioinformatics — Posted on 2024-01-15

2536 Thermal Tolerance Plasticity and Dynamics of Thermal Tolerance in Eublepharis macularius: Implications for Future Climate-Driven Heat Stress

White, E.; Kim, S.; Wegh, G.; Chiari, Y.

10.1101/2024.01.13.575519 — zoology — Posted on 2024-01-15

2537 Comprehensive benchmark of differential transcript usage analysis for static and dynamic conditions

Lio, C. T.; Duez, T.; Hoffmann, M. D.; Willruth, L.-L.; Baumbach, J.; Tsoy, O.; List, M.

10.1101/2024.01.14.575548 — bioinformatics — Posted on 2024-01-15

2538 Targeted Perturb-seq Reveals EGR1 and FOS as Key Regulators of the Transcriptional RAF-MAPK Response

El Kassem, G.; Sieber, A.; Klinger, B.; Uhlitz, F.; Steinbrecht, D.; van Bentum, M.; Hillmer, J.; von Schlichting, J.; Schäfer, R.; Blüthgen, N.; Boettcher, M.

10.1101/2024.01.13.575500 — systems biology — Posted on 2024-01-15

2539 FLAb: Benchmarking deep learning methods for antibody fitness prediction

Chungyoun, M.; Ruffolo, J. A.; Gray, J. J.

10.1101/2024.01.13.575504 — bioinformatics — Posted on 2024-01-15

2540 Crosstalk interactions between transcription factors ERRalpha and PPARalpha assist PPARalpha-mediated gene expression

Desmet, S. J.; Thommis, J.; Vanderhaeghen, T.; Vandenboorn, E. M.; Li, Y.; Timmermans, S.; Fijalkowska, D.; Ratman, D.; Van Hamme, E.; De Cauwer, L.; Staels, B.; Brunsveld, L.; Peelman, F.; Libert, C.; Tavernier, J.; De Bosscher, K.

10.1101/2024.01.15.575655 — molecular biology — Posted on 2024-01-15

2541 Multiomic Data Integration Reveals Microbial Drivers of Aetiopathogenesis in Mycosis Fungoides

Licht, P.; Mailaender, V.

10.1101/2024.01.15.575621 — systems biology — Posted on 2024-01-15

2542 Inferring the selective history of CNVs using a maximum likelihood model

Malekpour, S. A.; Kalirad, A.; Majidian, S.

10.1101/2024.01.15.575676 — bioinformatics — Posted on 2024-01-15

2543 Spatial Transcriptomics Sequencing of Mouse Liver at 2 Micron Resolution Using a Novel Spatial DNA Chip

Ding, X.; Hoff, K.; Swaminathan, R.; Pollom, S.; Huang, T.; Li, X.; Zhou, G.; Bai, Z.; Yu, S.; Xia, Z.; Koutrouli, M.; Jensen, L. J.; Crnogorac, F.; Yu, S.; McGall, G.; Edwards, J.; Zhou, W.

10.1101/2024.01.08.574734 — genomics — Posted on 2024-01-15

2544 Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy

Verma, N.; Renauer, P. A.; Dong, C.; Xin, S.; Lin, Q.; Zhang, F.; Glazer, P. M.; Chen, S.

10.1101/2024.01.14.575614 — genetics — Posted on 2024-01-15

2545 Biomechanical properties of defence vibrations produced by bees

Vallejo-Marin, M.; Field, D. L.; Fornoni, J.; Montesinos, D.; Dominguez, C. A.; Baltazar, I.; Vallejo, G. C.; Woodrow, C.; Ayala, R.; Jafferis, N.

10.1101/2024.01.15.575671 — ecology — Posted on 2024-01-15

2546 Pixel Walking along the boreal forest-Arctic tundra ecotone: Large scale ground-truthing of satellite-derived greenness (NDVI)

Wong, R. E.; Berner, L. T.; Sullivan, P. F.; Potter, C. S.; Dial, R. J.

10.1101/2024.01.14.574721 — ecology — Posted on 2024-01-15

2547 CD4 T Cells Acquire Cytotoxic Properties to Modulate Cellular Senescence and Aging

Elyahu, Y.; Feygin, I.; Pinkas, N.; Zemer, A.; Shicht, A.; Berner, O.; Eremenko, E.; Nemirovsky, A.; Reshef, K.; Roitman, L.; Krizhanovsky, V.; Monsonego, A.

10.1101/2024.01.14.575313 — immunology — Posted on 2024-01-15

2548 mRNA-LNP COVID-19 vaccine lipids induce low level complement activation and production of proinflammatory cytokines: Mechanisms, effects of complement inhibitors, and relevance to adverse reactions

Bakos, T.; Meszaros, T.; Kozma, G. T.; Berenyi, P.; Facsko, R.; Farkas, H.; Dezsi, L.; Heirman, C.; de Koker, S.; Schiffelers, R.; Glatter, K. A.; Radovits, T.; Szenasi, G.; Szebeni, J.

10.1101/2024.01.12.575122 — immunology — Posted on 2024-01-15

2549 Neonatal sensitivity to vocal emotions: A milestone at 37 weeks of gestational age

Hou, X.; Zhang, P.; Mo, L.; Peng, C.; Zhang, D.

10.1101/2024.01.14.575448 — neuroscience — Posted on 2024-01-15

2550 Altering subjective time perception leads to correlated changes in neural activity and delay discounting impulsivity

Lee, S.; Kable, J. W.; Jung, W. H.

10.1101/2024.01.14.575587 — neuroscience — Posted on 2024-01-15

2551 De novo-designed minibinders expand the synthetic biology sensing repertoire

Weinberg, Z. Y.; Soliman, S. S.; Kim, M. S.; Chen, I. P.; Ott, M.; El-Samad, H.

10.1101/2024.01.12.575267 — synthetic biology — Posted on 2024-01-15

2552 A functional medicine and food homology composition discovery based on disease-related target and data mining against cardiac remodeling

Xiao, D.; Li, R.; Qin, X.; Feng, J.; Baranenko, D.; Natdochii, L.; Liu, J.; Zhou, Y.; Lin, Y.

10.1101/2024.01.14.575612 — pharmacology and toxicology — Posted on 2024-01-15

2553 Functional diversity in the Hsp60 of Sulfolobus acidocaldarius: mosaic of Group I and Group II chaperonin

Bhakta, K.; Roy, M.; Samanta, S.; Ghosh, A.

10.1101/2024.01.14.575554 — biochemistry — Posted on 2024-01-15

2554 Can social interactions rescue "lost" behavioural defences in an allopatric cuckoo host?

Tolman, D.; Rönkä, K.; Kluen, E.; Campobello, D.; Thorogood, R.

10.1101/2024.01.14.575589 — animal behavior and cognition — Posted on 2024-01-15

2555 Zooplankton impacts on the persistence of the anthropogenic pollution marker intI1 in lake water

Borgomaneiro, G.; Di Cesare, A.; Callieri, C.; Corno, G.; Fontaneto, D.; Piscia, R.; Eckert, E. M.

10.1101/2024.01.15.575667 — ecology — Posted on 2024-01-15

2556 A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism

Salvi Mesa, D.; Barbieri, E.; Raimondi, A.; Freddi, S.; Miloro, G.; Jendrisek, G.; Caldieri, G.; Quarto, M.; Schiano Lomoriello, I.; Malabarba, M. G.; Bresci, A.; Manetti, F.; Vernuccio, F.; Abdo, H.; Scita, G.; Polli, D.; Tacchetti, C.; Pinton, P.; Bonora, M.; Di Fiore, P. P.; Sigismund, S.

10.1101/2024.01.15.574804 — cell biology — Posted on 2024-01-15

2557 Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2

Xu, L.; Yu, D.; Xu, M.; Yang, L.-X.; Zou, Q.-C.; Feng, X.-L.; Li, M.-H.; Sheng, N.; Yao, Y.-G.

10.1101/2024.01.13.575537 — cell biology — Posted on 2024-01-15

2558 Live-cell fluorescence imaging and optogenetic control of PKA kinase activity in fission yeast Schizosaccharomyces pombe.

Sakai, K.; Aoki, K.; Goto, Y.

10.1101/2024.01.14.575615 — cell biology — Posted on 2024-01-15

2559 Chromatin remodeling initiates transcriptional and post-transcriptional silencing in Neurospora

Carlier, F.; Castro Ramirez, S.; Kilani, J.; Chehboub, S.; Gladyshev, E.

10.1101/2024.01.15.575522 — molecular biology — Posted on 2024-01-15

2560 MicroRNA-focused CRISPR/Cas9 Screen Identifies miR-142 as a Key Regulator of Epstein-Barr Virus Reactivation

Chen, Y.; Kincaid, R. P.; Bastin, K.; Fachko, D. N.; Skalsky, R.

10.1101/2024.01.15.575629 — molecular biology — Posted on 2024-01-15

2561 On the ecology of Acinetobacter baumannii - jet stream rider and opportunist by nature

Wilharm, G.; Skiebe, E.; Lopinska, A.; Higgins, P. G.; Weber, K.; Schaudinn, C.; Neugebauer, C.; Goerlitz, K.; Meimers, G.; Rizova, Y.; Blaschke, U.; Heider, C.; Cuny, C.; Drewes, S.; Heuser, E.; Jeske, K.; Jacob, J.; Ulrich, R. G.; Bochenski, M.; Kasprzak, M.; Burda, E.; Cieplinski, M.; Kaluga, I.; Jankowiak, L.; Aguirre, J. I.; Lopez-Garcia, A.; Hoefle, U.; Jagiello, Z.; Tobolka, M.; Janic, B.; Zielinski, P.; Kaminski, M.; Frisch, J.; Siekiera, J.; Wendel, A. F.; Brauner, P.; Jaeckel, U.; Kaatz, M.; Mueller, S.; Luebke-Becker, A.; Wieler, L. H.; von Wachsmann, J.; Thrukonda, L.; Helal, M.; E

10.1101/2024.01.15.572815 — microbiology — Posted on 2024-01-15

2562 Distinct chikungunya virus polymerase palm subdomains contribute to virus replication and virion assembly

Martin, M.-F.; Bonaventure, B.; McCray, N. E.; Peersen, O. B.; Rozen-Gagnon, K.; Stapleford, K.

10.1101/2024.01.15.575630 — microbiology — Posted on 2024-01-15

2563 Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2

Desai, P.; Karl, C. E.; Ying, B.; Liang, C.-Y.; Garcia-Salum, T.; Santana, A. C.; Caten, F. T.; Urban, J. F.; Elbashir, S. M.; Edwards, D. K.; Ribeiro, S. P.; Thackray, L. B.; Sekaly, R.-P. K.; Diamond, M. S.

10.1101/2024.01.14.575588 — immunology — Posted on 2024-01-15

2564 Endogenous glucocorticoids are required for normal macrophage activation and gastric Helicobacter pylori immunity

Khadka, S.; Dziadowicz, S. A.; Xu, X.; Lei, W.; Hu, G.; Busada, J. T.

10.1101/2024.01.14.575574 — immunology — Posted on 2024-01-15

2565 Translation initiation or elongation inhibition triggers contrasting effects on Caenorhabditis elegans survival during pathogen infection

Ghosh, A.; Singh, J.

10.1101/2024.01.15.575653 — immunology — Posted on 2024-01-15

Hastings, W. L.; Willbrand, E. H.; Elliott, M. V.; Johnson, S. L.; Weiner, K. S.

10.1101/2024.01.14.574481 — neuroscience — Posted on 2024-01-15

2567 Individual Differences in Belief Updating and Phasic Arousal Are Related to Psychosis Proneness

Murphy, P. R.; Krkovic, K.; Monov, G.; Kudlek, N.; Lincoln, T.; Donner, T. H.

10.1101/2024.01.14.575567 — neuroscience — Posted on 2024-01-15

2568 ARViS: A bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset brains

Nomura, S.; Terada, S.-I.; Ebina, T.; Uemura, M.; Masamizu, Y.; Ohki, K.; Matsuzaki, M.

10.1101/2024.01.15.575593 — neuroscience — Posted on 2024-01-15

2569 Recombinant venom proteins in insect seminal fluid reduces female lifespan

Beach, S. J.; Maselko, M.

10.1101/2024.01.14.575309 — synthetic biology — Posted on 2024-01-15

2570 Harnessing the power of poplar tree natural genetic variation for the development of future sustainable biofuels and bioproducts: a droughted marginal-land experiment for multi-disciplinary investigations

Taylor, G.; Bailey-Bale, J. H.; Milner, S.; Klein, M. C.; Chen, J.-G.; Muchero, W.; Freer-Smith, P. H.; Tschaplinski, T. J.; Tuskan, G. A.

10.1101/2024.01.11.575272 — plant biology — Posted on 2024-01-15

2571 PathFinder: a novel graph transformer model to infer multi-cell intra- and inter-cellular signaling pathways and communications

Feng, J.; Province, M.; Li, G.; Payne, P. R.; Chen, Y.; Li, F.

10.1101/2024.01.13.575534 — bioinformatics — Posted on 2024-01-15

2572 Chromosomal-level genome assembly of golden birdwing Troides aeacus (Felder & Felder, 1860)

10.1101/2024.01.13.575334 — genomics — Posted on 2024-01-15

2573 Relaxed selection and horizontal gene transfer fuel underwater adaptation in a water spider

Fan, Z.; Wang, L.-Y.; Luo, B.; Ren, T.-Y.; Gao, J.-X.; Liu, P.; Cheng, L.-X.; Cai, Y.-J.; Tan, B.; Huang, Q.; Deng, M.-Q.; Zuo, Q.; Zhang, X.-Y.; Lu, J.-Z.; Sun, L.-N.; Irfan, M.; Liu, N.; Tong, C.; Bai, M.; Zhang, Z.-S.

10.1101/2024.01.15.575295 — genomics — Posted on 2024-01-15

2574 Transposon-mediated genic rearrangements underlie variation in small RNA pathways

Zhang, G.; Felix, M.-A.; Andersen, E. C.

10.1101/2024.01.15.575659 — genomics — Posted on 2024-01-15

2575 Comparative pangenome analysis of major pneumococcal genotypes from India

Peela, S. C. M.; Sistla, S.

10.1101/2024.01.14.575557 — genomics — Posted on 2024-01-15

2576 Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism

Nshanian, M.; Geller, B. S.; Gruber, J. J.; Chleilat, F.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.

10.1101/2024.01.11.575111 — genetics — Posted on 2024-01-15

2577 The probability of a unique gene occurrence at the tips of a phylogenetic tree in the absence of horizontal gene transfer (the last-one-out)

Bremer, N.; Martin, W. F.; Steel, M.

10.1101/2024.01.14.575579 — evolutionary biology — Posted on 2024-01-15

2578 Experimental evaluation of a direct fitness effect of the de novo evolved mouse gene Pldi

Linnenbrink, M.; Breton, G.; Pfeifle, C.; Misra, P.; Dutheil, J. Y.; Tautz, D.

10.1101/2024.01.13.575362 — evolutionary biology — Posted on 2024-01-15

2579 Studies on Human-Coronavirus protein-protein interaction network from the perspective of viral adaptation in a novel host

Acharya, D.; Dutta, T. K.

10.1101/2024.01.12.575398 — evolutionary biology — Posted on 2024-01-15

2580 Indicators to assess interannual variability in marine connectivity processes: a semi-theoretical approach

Clavel-Henry, M.; Bahamon, N.; Aguzzi, J.; Navarro, J.; Lopez, M.; Company, J. B.

10.1101/2024.01.12.575479 — ecology — Posted on 2024-01-15

2581 Acoustic Signatures of the Cerrado: Machine Learning Reveals Unique Soundscapes Across Diverse Phytogeographies

Daleffi da Silva, B.; Padovese, L. R.

10.1101/2024.01.12.575467 — ecology — Posted on 2024-01-15

2582 Resource-explicit interactions in spatial population models

Champer, S. E.; Chae, B.; Haller, B. C.; Champer, J.; Messer, P. W.

10.1101/2024.01.13.575512 — ecology — Posted on 2024-01-15

2583 Enhancing marine resilience in temperate coastal systems requires the implementation of multiple management strategies

Sanabria-Fernandez, J. A.; Lazzari, N.

10.1101/2024.01.13.575496 — ecology — Posted on 2024-01-15

2584 Computational Transcriptomic and Comparative Genomic Analysis of dead box RNA Helicase gene AT2G45810 Expressed in Plants Arabidopsis thaliana

Emon, M.; Hosen, A.; Bhajan, S. K.; Ali, M. S.; Ahmed Jewel, Z.

10.1101/2024.01.12.575476 — developmental biology — Posted on 2024-01-15

2585 Morphologically defined substages of tail tip morphogenesis in C. elegans males

Kiontke, K. C.; Fernandez, P.; Woronik, A.; Fitch, D. H. A.

10.1101/2024.01.11.575265 — developmental biology — Posted on 2024-01-15

2586 Generation of natural killer and myeloid cells in a 3D artificial marrow organoid system

Schell, B.; Zhao, L. P.; Kergaravat, C.; Lereclus, E.; Kalogeraki, M.; Fenaux, P.; Ades, L.; Toubert, A.; Espeli, M.; Balabanian, k.; Clave, E.; Dulphy, N.; Bisio, V.

10.1101/2024.01.15.575527 — cell biology — Posted on 2024-01-15

2587 A scaleable inducible knockout systemfor studying essential gene function inthe malaria parasite

Ramaprasad, A.; Blackman, M.

10.1101/2024.01.14.575607 — microbiology — Posted on 2024-01-15

2588 Lipid nanoparticle composition for adjuvant formulation modulates disease after influenza virus infection in QIV vaccinated mice.

Jangra, S.; Lamoot, A.; Singh, G.; Laghlali, G.; Chen, Y.; Ye, T.; Garcia-Sastre, A.; De Geest, B. G.; Schotsaert, M.

10.1101/2024.01.14.575599 — microbiology — Posted on 2024-01-15

2589 PIEZO1-mediated mechanosensing governs NK cell killing efficiency in 3D

Yanamandra, A. K.; Zhang, J.; Montalvo, G.; Zhou, X.; Biedenweg, D.; Zhao, R.; Sharma, S.; Hoth, M.; Lautenschlaeger, F.; Otto, O.; del Campo, A.; Qu, B.

10.1101/2023.03.27.534435 — immunology — Posted on 2024-01-15

2590 Different vaccine platforms result in distinct antibody responses to the same antigen in haemodialysis patients

Wall, N.; Lamerton, R.; Ashford, F.; Perez-Toledo, M.; Jasiulewicz, A.; Banham, G.; Newby, M. L.; Faustini, S. E.; Richter, A.; Selvaskandan, H.; Billany, R.; Adenwalla, S.; Henderson, I. R.; Crispin, M.; Graham-Brown, M.; Harper, L.; Cunningham, A. F.

10.1101/2024.01.14.575569 — immunology — Posted on 2024-01-15

2591 Intricate response dynamics enhances stimulus discrimination in the resource-limited C. elegans chemosensory system

Bokman, E.; Pritz, C.; Ruach, R.; Itskovits, E.; Sharvit, H.; Zaslaver, A.

10.1101/2024.01.14.575365 — neuroscience — Posted on 2024-01-15

2592 Generation and benchmarking of a collection of hiPSC lines from Schizophrenia Patients with Diverse Clinical Profiles

Vecchi, E. R.; Olmeda, C. V.; Bottai, D.; Finelli, P.; Salavarria, M. M. A.; Gervasini, C.; Mangiaterra, L.; Lombardi, F.; Sanguineti, C.; Onorati, M.; Conti, L.; D'Agostino, A.

10.1101/2024.01.14.575590 — neuroscience — Posted on 2024-01-15

2593 Vaping and smoking cue reactivity in young adult electronic cigarette users who have never smoked combustible cigarettes: a functional neuroimaging study

Liu, J.; Shi, Z.; Fabbricatore, J. L.; McMains, J. T.; Worsdale, A.; Jones, E. C.; Wang, Y.; Sweet, L. H.

10.1101/2024.01.13.575524 — neuroscience — Posted on 2024-01-15

2594 Pupil size and eye movements differently index effort in both younger and older adults

Herrmann, B.; Ryan, J. D.

10.1101/2024.01.13.575506 — neuroscience — Posted on 2024-01-15

2595 Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling

Biswas, S.; Shahriar, S.; Bachay, G.; Arvanitis, P.; Jamoul, D.; Brunken, W. J.; Agalliu, D.

10.1101/2023.07.10.548410 — neuroscience — Posted on 2024-01-15

2596 Aphid resistance segregates independently of cardiac glycoside and glucosinolate content in an Erysimum cheiranthoides (wormseed wallflower) F2 population

Mirzaei, M.; Younkin, G. C.; Powell, A. F.; Alani, M. L.; Strickler, S. R.; Jander, G.

10.1101/2024.01.11.575310 — plant biology — Posted on 2024-01-15

2597 IOBR2: Multidimensional Decoding Tumor Microenvironment for Immuno-Oncology Research

Zeng, D.; Fang, Y.; Luo, P.; Qiu, W.; Wang, S.; Shen, R.; Gu, W.; Huang, X.; Mao, Q.; Lai, Y.; Xu, X.; Shi, M.; Yu, G.; Liao, W.

10.1101/2024.01.13.575484 — cancer biology — Posted on 2024-01-15

2598 IL6 mediated cFLIP downregulation increases the migratory and invasive potential of triple negative breast cancer cell line

Sinha, S.; Roy, R.; Barman, N.; Sarkar, P.; Saha, A.; Biswas, N.

10.1101/2024.01.14.575471 — cancer biology — Posted on 2024-01-15

2599 The Alzheimer's Aβ peptide forms biomolecular condensates that trigger amyloid aggregation

Sneideriene, G.; Gonzalez Diaz, A.; Adhikari, S. D.; Wei, J.; Michaels, T.; Sneideris, T.; Linse, S.; Vendruscolo, M.; Garai, K.; Knowles, T.

10.1101/2024.01.14.575549 — biophysics — Posted on 2024-01-15

2600 IN SILICO DESIGN AND BINDING MECHANISM OF E3 LIGASE UBR1 RECRUITERS

Maria Solano, M. A.; Lazim, R.; Choi, S.

10.1101/2024.01.14.575594 — biophysics — Posted on 2024-01-15

2601 CEL: A Continual Learning Model for Disease Outbreak Prediction by Leveraging Domain Adaptation via Elastic Weight Consolidation

Aslam, S.; Rasool, A.; Wu, H.; Li, X.

10.1101/2024.01.13.575497 — bioinformatics — Posted on 2024-01-15

2602 BAMBI: Integrative biostatistical and artificial-intelligence method discover coding and non-coding RNA genes as biomarkers

Zhou, P.; Li, Z.; Liu, F.; Kwon, E.; Hsieh, T.-C.; Ye, S.; Vasudevan, S.; Lee, J.; Zhou, C.

10.1101/2024.01.12.575460 — bioinformatics — Posted on 2024-01-15

2603 Unveiling the role of Tdark genes in genetic diseases and phenotypes through bioinformatics-based functional enrichment and network analyses

Kafita, D.; Dzobo, K.; Nkhoma, P.; Sinkala, M.

10.1101/2024.01.13.575505 — bioinformatics — Posted on 2024-01-15

2604 GVRP: Genome Variant Refinement Pipeline for variant analysis in non-human species using machine learning

Choi, J.; Zhou, B.; Song, G.

10.1101/2024.01.14.575595 — bioinformatics — Posted on 2024-01-15

2605 Reformer: Deep learning model for characterizing protein-RNA interactions from sequence at single-base resolution

Shen, X.; Li, X.

10.1101/2024.01.14.575540 — bioinformatics — Posted on 2024-01-15

2606 False discovery rate control: Moving beyond the Benjamini-Hochberg method

Koner, S.; De Sarkar, N.; Laha, N.

10.1101/2024.01.13.575531 — bioinformatics — Posted on 2024-01-15

2607 Urban sensory conditions alter rival interactions and mate choice in urban and forest tungara frogs

Smit, J. A. H.; Thijssen, V.; Cronin, A. D.; Ellers, J.; Halfwerk, W.

10.1101/2024.01.13.575508 — animal behavior and cognition — Posted on 2024-01-15

2608 Metagenomics insights into microbial diversity shifts among seagrass sediments

Detcharoen, M.; Rattanachot, E.; Prathep, A.

10.1101/2024.01.14.574613 — ecology — Posted on 2024-01-15

2609 Targeted CRISPR-Cas9 screening identifies transcription factor network controlling murine haemato-endothelial fate commitment

Teske, M.; Wertheimer, T.; Butz, S.; Zwicky, P.; Mallona, I.; Elling, U.; Lancrin, C.; Becher, B.; Grosso, A. R.; Baubec, T.; Schmolka, N.

10.1101/2024.01.14.575582 — developmental biology — Posted on 2024-01-15

2610 Mitochondrial ncRNA LDL-805 declines in alveolar epithelial type 2 cells of chronic obstructive pulmonary disease patients.

Mathuram, T. L.; Su, Y.; Bard, J.; Perry, N. A.; Chen, C.-W.; Warren, M. T.; Linden, P. A.; Perry, Y.; Hatzoglou, M.; Wu, Y.; Blumental-Perry, A.

10.1101/2024.01.14.575591 — cell biology — Posted on 2024-01-15

2611 Host-induced cell wall remodelling impairs opsonophagocytosis of Staphylococcus aureus by neutrophils

Ledger, E. V. K.; Edwards, A. M.

10.1101/2023.03.15.532736 — microbiology — Posted on 2024-01-15

2612 Differentially polarized macrophages show diverse proangiogenic characteristics under normo- and hyperglycemic conditions

Shariatzadeh, M.; Payan Gomez, C.; Dik, W. A.; Leenen, P. J.

10.1101/2024.01.12.575474 — immunology — Posted on 2024-01-15

Shao, X.; Shou, Q.; Felix, K.; Ojogho, B.; Jiang, X.; Gold, B. T.; Herting, M.; Goldwaser, E. L.; Kochunov, P.; Hong, E.; Pappas, I.; Braskie, M.; Kim, H.; Cen, S.; Jann, K.; Wang, D. J.

10.1101/2024.01.12.575463 — neuroscience — Posted on 2024-01-15

2614 "Bayesian anchoring" and the fourfold pattern of risk attitudes

Fumarola, F.; Kusmierz, L.; Dekker, R.

10.1101/2024.01.13.575482 — neuroscience — Posted on 2024-01-15

2615 Non-Degenerate Two-Photon Imaging of Deep Rodent Cortex using Indocyanine Green in the water absorption window

Tomar, A.; Engelmann, S.; Woods, A. L.; Dunn, A. K.

10.1101/2024.01.13.575485 — neuroscience — Posted on 2024-01-15

2616 A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments

Loewinger, G.; Cui, E.; Lovinger, D. M.; Pereira, F.

10.1101/2023.11.06.565896 — neuroscience — Posted on 2024-01-15

2617 Value construction through sequential sampling explains serial dependencies in decision making

Zylberberg, A.; Bakkour, A.; Shohamy, D.; Shadlen, M. N.

10.1101/2024.01.13.575363 — neuroscience — Posted on 2024-01-15

2618 Kalium channelrhodopsins effectively inhibit neurons in the small model animals

Ott, S.; Xu, S.; Lee, N.; Hong, I. H. K.; Anns, J.; Suresh, D. D.; Zhang, Z.; Zhang, X.; Harion, R.; Ye, W. V.; Chandramouli, V.; Jesuthasan, S. J.; Saheki, Y.; Claridge-Chang, A.

10.1101/2024.01.14.575538 — neuroscience — Posted on 2024-01-15

2619 The multiverse of data preprocessing and analysis in graph-based fMRI: A systematic literature review of analytical choices fed into a decision support tool for informed analysis

Kristanto, D.; Burkhardt, M.; Thiel, C.; Debener, S.; Giessing, C.; Hildebrandt, A.

10.1101/2024.01.14.575565 — neuroscience — Posted on 2024-01-15

2620 Unveiling the regulatory role of GRP7 in ABA signal-mediated mRNA translation efficiency regulation

Zhang, J.; Xu, Y.; Tian, F.; He, C.; Yu, X.; Yang, X.; Ding, Y.; Xiao, J.

10.1101/2024.01.12.575370 — plant biology — Posted on 2024-01-15

2621 Fluorescence Lifetime Imaging for quantification of targeted drug delivery in varying tumor microenvironments

Verma, A.; Pandey, V.; Sherry, C.; James, C.; Matteson, K.; Smith, J. T.; Rudkouskaya, A.; Intes, X.; Barroso, M.

10.1101/2024.01.12.575453 — cancer biology — Posted on 2024-01-15

2622 Single-cell mapping links neurogenesis and angiogenesis in aggressive breast cancer

Wik, E.; Aziz, S.; Finne, K.; Kleftogiannis, D.; Askeland, C.; Knutsvik, G.; Winge, I.; Kruger, K.; Svanoe, A. A.; Birkeland, E.; Kjolle, S.; Davidsen, B.; Aas, T.; Stefansson, I. M.; Vethe, H.; Akslen, L. A.

10.1101/2022.01.28.477898 — cancer biology — Posted on 2024-01-15

2623 E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

Patterson, M. R.; Meijers, A. S.; Ryder, E. L.; Scarth, J. A.; Evans, D.; Turner, A. L.; Wasson, C. W.; Darell, J. E.; James, C. D.; Wang, M.; Ladbury, J. E.; Morgan, I. M.; Samson, A.; Morgan, E. L.; Macdonald, A.

10.1101/2024.01.08.574687 — cancer biology — Posted on 2024-01-15

2624 Pulsed low-dose-rate radiation (PLDR) reduces the tumor-promoting responses induced by conventional chemoradiation in pancreatic cancer-associated fibroblasts

Franco-Barraza, J.; Luong, T.; Wong, J. K.; Raghavan, K.; Handroff, E.; Vendramini-Costa, D. B.; Francescone, R.; Gardiner, J. C.; Meyer, J. E.; Cukierman, E.

10.1101/2024.01.13.575510 — cancer biology — Posted on 2024-01-15

2625 Astigmatism-based focus stabilisation with universal objective lens compatibility, extended operating range and nanometre precision

Rahmani, A.; Cox, T.; Thamaravelil Abhimanue Achary, A.; Ponjavic, A.

10.1101/2024.01.15.575442 — biophysics — Posted on 2024-01-15

2626 Differentiable simulation to develop molecular dynamics force fields for disordered proteins

Greener, J. G.

10.1101/2023.08.29.555352 — biophysics — Posted on 2024-01-15

2627 Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers

Kim, J. M.; Carcamo, C. C.; Jazani, S.; Xie, Z.; Feng, X. A.; Yamadi, M.; Poyton, M. F.; Holland, K. L.; Grimm, J. B.; Lavis, L. D.; Ha, T.; Wu, C.

10.1101/2023.06.13.544671 — biophysics — Posted on 2024-01-15

2628 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K

Zheng, L.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.

10.1101/2023.10.18.562890 — biophysics — Posted on 2024-01-15

2629 Biophysical modeling identifies an optimal hybrid amoeboid-mesenchymal phenotype for maximal T cell migration speeds

Alonso Matilla, R.; Provenzano, P.; Odde, D. J.

10.1101/2023.10.29.564655 — biophysics — Posted on 2024-01-15

2630 betAS: intuitive analysis and visualisation of differential alternative splicing using beta distributions

Ascensao-Ferreira, M.; Martins-Silva, R.; Saraiva-Agostinho, N.; Barbosa-Morais, N. L.

10.1101/2022.12.26.521935 — bioinformatics — Posted on 2024-01-15

2631 Rapid and label-free exosome analysis by surface-enhanced Raman spectroscopy using silver nanoparticle substrate based on selective laser ablation and melting of silver nanowire

Nam, H.; Park, J.-e.; Hwang, J. S.; Kim, S.; Kim, S. J.; Kim, S.; Yang, M.; Jeon, J. S.

10.1101/2024.01.13.575493 — bioengineering — Posted on 2024-01-15

2632 A Cytological F1 RNAi Screen for Defects in Drosophila melanogaster Female Meiosis

Gilliland, W. D.; Bowen, A. O.; May, D. P.; Conger, K. O.; Elrad, D.; Marciniak, M.; Mashburn, S. A.; Presbitero, G.; Welk, L. F.

10.1101/2024.01.12.575435 — genetics — Posted on 2024-01-15

2633 Sperm production and allocation in response to risk of sperm competition in the black soldier fly Hermetia illucens

Manas, F.; Labrousse, C.; Bressac, C.

10.1101/2023.06.20.544772 — evolutionary biology — Posted on 2024-01-15

2634 Urbanization of a subtropical island (Okinawa, Japan) alters physicochemical characteristics and disrupts microbial community dynamics in nearshore ecosystems

Mars Brisbin, M.; Dudley, K. L.; Yonashiro, Y.; Mitarai, S.; Ares, A.

10.1101/2024.01.12.575464 — ecology — Posted on 2024-01-15

2635 Decreased sarcomeric mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin action in type 2 diabetes

Rizo-Roca, D.; Guimaraes, D. S.; Pendergrast, L. A.; Di Leo, N.; Chibalin, A. V.; Maqdasy, S.; Ryden, M.; Naslund, E.; Zierath, J. R.; Krook, A.

10.1101/2024.01.11.575194 — physiology — Posted on 2024-01-15

2636 Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis

Maio, M.; Barros, J.; Joly, M.; Vahlas, Z.; Marin Franco, J. L.; Genoula, M.; Monard, S.; Vecchione, M. B.; Fuentes, F.; Gonzalez Polo, V.; Quiroga, M. F.; Vermeulen, M.; Vu Manh, T. P.; Argüello, R. J.; Inwentarz, S.; Musella, R.; Ciallella, L.; Gonzalez Montaner, P.; Palmero, D.; Lugo Villarino, G.; Sasiain, M. d. C.; Neyrolles, O.; Verollet, C.; Balboa, L.

10.1101/2023.04.03.535400 — immunology — Posted on 2024-01-15

2637 Curriculum learning inspired by behavioral shaping trains neural networks to adopt animal-like decision making strategies

Hocker, D. L.; Constantinople, C. M.; Savin, C.

10.1101/2024.01.12.575461 — neuroscience — Posted on 2024-01-15

2638 Unveiling the cell biology of hippocampal neurons with dendritic axon origin

Han, Y.; Thuenauer, R.; Gruenewald, K.; Mikhaylova, M.

10.1101/2023.09.14.557747 — neuroscience — Posted on 2024-01-15

2639 Strategic Debulking of the Femoral Stem Promotes Load Sharing Through Controlled Flexural Rigidity of the Implant Wall: Optimization of Design by Finite Element Analysis.

Sunavala-Dossabhoy, G.; Saba, B. M.; McCarthy, K. J.

10.1101/2024.01.12.575457 — bioengineering — Posted on 2024-01-15

2640 Methods for tagging an ectoparasite, the salmon louse Lepeophtheirus salmonis

Folk, A.; Mennerat, A.

10.1101/2023.08.31.555695 — ecology — Posted on 2024-01-15

2641 A non-invasive photoactivatable split-Cre recombinase system for genome engineering in zebrafish.

ELSAID, R.; Mikdache, A.; Diabangouaya, P.; Gros, G.; Hernandez, P.

10.1101/2023.06.23.546268 — developmental biology — Posted on 2024-01-15

2642 Prediction of Post Traumatic Epilepsy using MRI-based Imaging Markers

Akrami, H.; Cui, W.; Kim, P. E.; Heck, C. N.; Irimia, A.; Jebri, K.; Nair, D.; Leahy, R. M.; Joshi, A.

10.1101/2024.01.12.575454 — neuroscience — Posted on 2024-01-15

2643 A neural circuit architecture for rapid behavioral flexibility in goal-directed navigation

Dan, C.; Kappagantula, R.; Hulse, B. K.; Jayaraman, V.; Hermundstad, A. M.

10.1101/2021.08.18.456004 — neuroscience — Posted on 2024-01-15

2644 Loss of calpain 3 dysregulates store-operated calcium entry and its exercise response in mice

Villani, K. R.; Zhong, R.; Henley-Beasley, C. S.; Rastelli, G.; Boncompagni, S.; Barton, E. R.; Wei-LaPierre, L.

10.1101/2024.01.12.575391 — physiology — Posted on 2024-01-15

2645 Potent Estrogen Receptor β Agonists with Inhibitory Activity In Vitro, Fail to Suppress Xenografts of Endocrine-Resistant Cyclin-dependent Kinase 4/6 inhibitor-Resistant Breast Cancer Cells

Marcho, L. M.; Coss, C. C.; Xu, M.; Datta, J.; Manouchehri, J. M.; Cherian, M. A.

10.1101/2024.01.12.575428 — cancer biology — Posted on 2024-01-15

2646 ArborSim: Articulated, branching, OpenSim routing for constructing models of multi-jointed appendages with complex muscle-tendon architecture

Fu, X.; Withers, J.; Miyamae, J.; Moore, T.

10.1101/2024.01.13.575515 — biophysics — Posted on 2024-01-15

2647 Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins

Khakimzhan, A.; Izri, Z.; Thompson, S.; Dmytrenko, O.; Fischer, P.; Beisel, C.; Noireaux, V.

10.1101/2024.01.14.575553 — biophysics — Posted on 2024-01-15

2648 ATP-Binding Free Energy Simulations Reveal an Allosteric Link Between the Enzyme Active Site and Multiple Functional Protein-Protein Interaction Interfaces in Cyclin Dependent Kinase-1

Vishwakarma, K. K.; Kolthur-Seetharam, U.; Venkatramani, R.

10.1101/2024.01.15.575662 — biophysics — Posted on 2024-01-15

2649 Multi-condensate state as a functional strategy to optimize the cell signaling output

Chattaraj, A.; Shakhnovich, E. I.

10.1101/2024.01.14.575571 — biophysics — Posted on 2024-01-15

2650 Mechanistic Insights into G-protein Activation via Phosphorylation Mediated Non-Canonical Pathway

Shewani, K.; Madhu, M. K.; Murarka, R. K.

10.1101/2024.01.15.575647 — biophysics — Posted on 2024-01-15

2651 TransMEP: Transfer learning on large protein language models to predict mutation effects of proteins from a small known dataset

Hoffbauer, T.; Strodel, B.

10.1101/2024.01.12.575432 — bioinformatics — Posted on 2024-01-15

2652 A method to identify high consensus predictions of single-cell metabolic flux

Amiss, J. M. B.; Jabbari, H.; Lum, J.

10.1101/2024.01.15.572211 — bioinformatics — Posted on 2024-01-15

2653 Mitigating reactive oxygen species production and increasing gel porosity improves lymphocyte motility and fibroblast spreading in photocrosslinked gelatin-thiol hydrogels

Ozulumba, T.; Zatorski, J. M.; Arneja, A.; Hammel, J. H.; Braciale, T. J.; Luckey, C. J.; Munson, J. M.; Pompano, R. R.

10.1101/2024.01.14.574282 — bioengineering — Posted on 2024-01-15

2654 Integrative analysis of Hydra head regeneration reveals actions of conserved signaling pathways and transposable elements

Macias-Munoz, A.; Mesrop, L. Y.; Liang, H. Y.; Mortazavi, A.

10.1101/2022.05.17.492329 — genomics — Posted on 2024-01-15

2655 Revisiting the invasion paradox: resistance-richness relationship is driven by augmentation and displacement trends

Zhu, Y.; Momeni, B.

10.1101/2024.01.12.575455 — ecology — Posted on 2024-01-15

2656 2018-2019 human seasonal H3N2 influenza A virus spillovers into swine with demonstrated virus transmission in pigs were not sustained in the pig population

Powell, J. D.; Thomas, M. N.; Anderson, T. K.; Zeller, M. A.; Gauger, P. C.; Vincent Baker, A. L.

10.1101/2024.01.12.575431 — microbiology — Posted on 2024-01-15

2657 AnNoBrainer, an Automated Annotation of Mouse Brain Images using Deep Learning

Peter, R.; Hrobar, P.; Navratil, J.; Vagenknecht, M.; Soukup, J.; Tsuji, K.; Barrezueta, N.; Stoll, A.; Gentzel, R.; Sungam, J.; Marcus, J.; Bitton, D. A.

10.1101/2024.01.12.575415 — neuroscience — Posted on 2024-01-15

2658 How altricial birds respond to a heat challenge: organismal perspectives on coping with a future climate scenario

Woodruff, M. J.; Tsueda, S. N.; Cutrell, T. S.; Guardado, E. A.; Rusch, D. B.; Buechlein, A.; Rosvall, K. A.

10.1101/2024.01.11.575240 — physiology — Posted on 2024-01-15

2659 Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

Ewing, A.; Meynert, A.; Silk, R.; Aitken, S.; Bendixsen, D. P.; Churchman, M.; Brown, S. L.; Hamdan, A.; Mattocks, J.; Grimes, G. R.; Ballinger, T.; Hollis, R. L.; Herrington, C. S.; Thomson, J. P.; Sherwood, K.; Parry, T.; Esiri-Bloom, E.; Bartos, C.; Croy, I.; Ferguson, M.; Lennie, M.; McGoldrick, T.; McPhail, N.; Siddiqui, N.; Glasspool, R.; Mackean, M.; Nussey, F.; McDade, B.; Ennis, D.; The Scottish Genomes Partnership, ; McMahon, L.; Matakidou, A.; Dougherty, B.; March, R.; Barrett, J. C.; McNeish, I. A.; Biankin, A. V.; Roxburgh, P.; Gourley, C.; Semple, C. A.

10.1101/2024.01.12.575376 — cancer biology — Posted on 2024-01-15

2660 A genuinely hybrid, multiscale 3D cancer invasion and metastasis modelling framework

Katsaounis, D.; Harbour, N.; Williams, T.; Chaplain, M. A.; Sfakianakis, N.

10.1101/2024.01.12.575361 — cancer biology — Posted on 2024-01-15

2661 The Molecular Picture of the Local Environment in a Stable Model Coacervate

Baksi, A.; Zerze, H.; Agrawal, A.; Karim, A.; Zerze, G. H.

10.1101/2024.01.12.575416 — biophysics — Posted on 2024-01-15

2662 SnapFISH-IMPUTE: an imputation method for multiplexed DNA FISH data

Yu, H.; Wu, D.; Shen, G.; Hu, M.; Li, Y.

10.1101/2024.01.12.575427 — bioinformatics — Posted on 2024-01-15

2663 A user-friendly input-output (IO) curve analysis tool for variable brain stimulation responses, particularly evoked potentials in transcranial magnetic stimulation (TMS)

Ma, K.; Goetz, S. M.

10.1101/2024.01.12.575452 — bioinformatics — Posted on 2024-01-15

2664 Identification, characterization and transcriptional analysis of long non-coding RNAs in Cucurbits

Villalba-Bermell, P.; Marques-Molins, J.; Gomez, G.

10.1101/2024.01.12.575433 — bioinformatics — Posted on 2024-01-15

2665 Pharmacological validation of an attention bias test for conventional broiler chickens

Lourenco da Silva, M. I.; Ulans, A.; Jacobs, L.

10.1101/2024.01.12.575423 — animal behavior and cognition — Posted on 2024-01-15

2666 Sonic restoration: Acoustic stimulation enhances soil fungal biomass and activity of plant growth-promoting fungi

Robinson, J. M.; Cando-Dumancela, C.; Breed, M. F.

10.1101/2024.01.11.575298 — ecology — Posted on 2024-01-15

2667 Competitive fungal commensalism mitigates candidiasis pathology

Kralova, J. S.; Donic, C.; Dassa, B.; Livyatan, I.; Jansen, P.; Ben-Dor, S.; Fidel, E.; Trzebanski, S.; Narunsky-Haziza, L.; Assaf, O.; Brenner, O.; Dafni, H.; Jona, G.; Boura-Halfon, S.; Stettner, N.; Segal, E.; Brunke, S.; Pilpel, Y. T.; Straussman, R.; Zeevi, D.; Bacher, P.; Hube, B.; Shlezinger, N.; Jung, S.

10.1101/2024.01.12.575358 — immunology — Posted on 2024-01-15

2668 Retinal input is required for the maintenance of neuronal laminae in the ventral lateral geniculate nucleus

Stebbins, K.; Somaiya, R. D.; Sabbagh, U.; Liang, Y.; Su, J.; Fox, M. A.

10.1101/2024.01.12.575402 — neuroscience — Posted on 2024-01-15

2669 Cannabinoid type-1 (CB1) receptors in glial cells promote neuromuscular junction repair following nerve injury.

Piovesana, R.; Charron, S.; Arbour, D.; Marsicano, G.; Bellocchio, L.; Robitaille, R.

10.1101/2024.01.12.575382 — neuroscience — Posted on 2024-01-15

2670 Individualized functional localization of the language and multiple demand network in chronic post-stroke aphasia

De Clercq, P.; Gonsalves, A. R.; Gerrits, R.; Vandermosten, M.

10.1101/2024.01.12.575350 — neuroscience — Posted on 2024-01-15

2671 Mathematical Modeling of Drug Delivery from Bi-Layered Core-Shell Polymeric Microspheres

Chacin Ruiz, E. A.; Carpenter, S. L.; Swindle-Reilly, K. E.; Ford Versypt, A. N.

10.1101/2024.01.11.575289 — pharmacology and toxicology — Posted on 2024-01-15

2672 Impact of occluder device configurations in in-silico left atrial hemodynamics for the analysis of device-related thrombus

Albors, C.; Mill, J.; Olivares, A. L.; Iriart, X.; Cochet, H.; Camara, O.

10.1101/2024.01.11.575154 — bioengineering — Posted on 2024-01-15

2673 Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men

Janivara, R.; Hazra, U.; Pfennig, A.; Harlemon, M.; Kim, M. S.; Eaaswarkhanth, M.; Chen, W. C.; Ogunbiyi, A.; Kachambwa, P.; Petersen, L. N.; Jalloh, M.; Mensah, J. E.; Adjei, A. A.; Adusei, B.; Joffe, M.; Gueye, S. M.; Aisuodionoe-Shadrach, O. I.; Fernandez, P. W.; Rohan, T. E.; Andrews, C.; Rebbeck, T. R.; Adebiyi, A. O.; Agalliu, I.; Lachance, J.

10.1101/2024.01.12.575396 — genomics — Posted on 2024-01-15

2674 Species delimitation analysis indicates cryptic speciation for Terpios gelatinosus (Porifera, Demospongiae) from coastal regions of the northeastern Mediterranean Sea

Ozturk, E.; Temiz, B.; Karahan, A.

10.1101/2024.01.12.575186 — evolutionary biology — Posted on 2024-01-15

2675 Reproductive innovation enabled radiation in the deep sea during an ecological crisis

Brownstein, C.; Zapfe, K.; Lott, S.; Harrington, R. C.; Ghezelayagh, A.; Dornburg, A.; Near, T. J.

10.1101/2024.01.12.575380 — evolutionary biology — Posted on 2024-01-15

2676 Clear effects of population and sex but not rearing temperature on stress tolerance in a temperate butterfly

Verspagen, N.; DiLeo, M. F.; Saastamoinen, M.

10.1101/2024.01.12.575354 — evolutionary biology — Posted on 2024-01-15

2677 Modelling biological and resource fluxes in fluvial meta-ecosystems

Talluto, M.; del Campo, R.; Estevez, E.; Fuss, T.; Thuile Bistarelli, L.; Martini, J.; Singer, G. A.

10.1101/2024.01.12.575367 — ecology — Posted on 2024-01-15

2678 Circatidal control of gene expression in the deep-sea hot vent shrimp Shinkaicaris leurokolos

Zhang, H.; Yahagi, T.; Miyamoto, N.; Chen, C.; Qian, P.-Y.; Sun, J.

10.1101/2024.01.12.575359 — ecology — Posted on 2024-01-15

2679 Complex interspecific interactions influence the interactions between pest control and pollination in coffee agroecosystems.

Vaidya, C.; Dominguez Martine, G.; Vandermeer, J.

10.1101/2024.01.12.575383 — ecology — Posted on 2024-01-15

2680 Tviblindi algorithm identifies branching developmental trajectories of human B cell development

Bakardjieva, M.; Stuchly, J.; Pelak, O.; Wentink, M.; Glier, H.; Novak, D.; Stancikova, J.; Kuzilkova, D.; Janowska, I.; Rizzi, M.; Burg, M. v. d.; Kalina, T.

10.1101/2024.01.11.575178 — immunology — Posted on 2024-01-15

2681 Identification of a distinct cluster of GDF15high macrophages exhibiting anti-inflammatory activities

Dai, C.; Zhang, H.; Zheng, Z.; Li, C.-G.; Ma, M.; Gao, H.; Zhang, Q.; Cui, X.; Jiang, F.

10.1101/2024.01.11.575315 — immunology — Posted on 2024-01-15

2682 Mitochondrial metabolism sustains CD8+ T cellmigration for an efficient infiltration into solid tumors

Simula, L.; Fumagalli, M.; Vimeux, L.; Rajnpreht, I.; Icard, P.; An, D.; Pendino, F.; Damotte, D.; Lupo-Mansuet, A.; Alifano, M.; Alves-Guerra, M.-C.; Donnadieu, E.

10.1101/2024.01.12.575327 — immunology — Posted on 2024-01-15

2683 Connectivity and functional diversity of different temporo-occipital nodes for action perception

Li, B.; Poyo Solanas, M.; Marrazzo, G.; de Gelder, B.

10.1101/2024.01.12.574860 — neuroscience — Posted on 2024-01-15

2684 Computational investigation of BMAA and its carbamate adducts as potential GluR2 modulators

Diakogiannaki, I.; Papadourakis, M.; Spyridaki, V.; Cournia, Z.; Koutselos, A.

10.1101/2024.01.12.575281 — pharmacology and toxicology — Posted on 2024-01-15

2685 Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma

Chattopadhyay, C.; Roszik, J.; Bhattacharya, R.; Alauddin, M.; Mahmud, I.; Yadugiri, S.; Ali, M. M.; Khan, F. S.; Prabhu, V. V.; Lorenzi, P.; Burton, E.; Morey, R. R.; Lazcano, R.; Davies, M. A.; Patel, S. P.; Grimm, E. A.

10.1101/2024.01.12.575058 — cancer biology — Posted on 2024-01-15

2686 Targeted intracellular delivery to hypoxic human breast cancer stem cells

Makela, A. V.; Tundo, A.; Liu, H. V.; Hermiston, T.; Contag, C. H.

10.1101/2024.01.12.575071 — cancer biology — Posted on 2024-01-15

2687 Integrated germline and somatic features reveal divergent immune pathways driving ICB response

Sears, T. J.; Pagadala, M.; Castro, A.; Lee, K.-H.; Kong, J.; Tanaka, K.; Lippman, S.; Zanetti, M. J.; Carter, H.

10.1101/2024.01.12.575430 — cancer biology — Posted on 2024-01-15

2688 A multi-scale feature fusion model based on biological knowledge graph and transformer-encoder for drug-drug interaction prediction

Wang, T.; Deng, Q.; Hu, J.; Wang, Y.; Peng, J.; Chen, J.; Shang, X.

10.1101/2024.01.12.575305 — bioinformatics — Posted on 2024-01-15

2689 PREDICTING GENE DISEASE ASSOCIATIONS WITH KNOWLEDGE GRAPH EMBEDDINGS FOR DISEASES WITH CURTAILED INFORMATION

Gualdi, F.; Oliva, B.; Pinero, J.

10.1101/2024.01.11.575314 — bioinformatics — Posted on 2024-01-15

2690 Bridging the Gap: Integrating Cutting-edge Techniques into Biological Imaging with deepImageJ

Fuster-Barcelo, C.; Garcia Lopez de Haro, C.; Gomez-de-Mariscal, E.; Ouyang, W.; Olivo-Marin, J.-C.; Sage, D.; Munoz-Barrutia, A.

10.1101/2024.01.12.575015 — bioinformatics — Posted on 2024-01-15

2691 Joint-specific rheumatoid arthritis fibroblast-like synoviocyte regulation identified by integration of chromatin access and transcriptional activity

Choi, E.; Machado, C. R. L.; Okano, T.; Boyle, D.; Wang, W.; Firestein, G. S.

10.1101/2024.01.12.575379 — bioinformatics — Posted on 2024-01-15

2692 Effect of molecular weight of tyramine-modified hyaluronan on polarization state of peripheral blood mononuclear cells-derived macrophages

Wychowaniec, J. K.; Bektas, E. I.; Vernengo, A. J.; Mürner, M.; Airoldi, M.; Eglin, D.; D'Este, M.

10.1101/2024.01.11.575241 — bioengineering — Posted on 2024-01-15

2693 A novel ionic model for matured and paced atrial-like hiPSC-CMs integrating IKur and IKCa currents

Botti, S.; Bartolucci, C.; Altomare, C.; Paci, M.; Barile, L.; Krause, R.; Pavarino, L. F.; Severi, S.

10.1101/2024.01.12.574782 — bioengineering — Posted on 2024-01-15

2694 Normalized level set model for segmentation of low-contrast objects in 2- and 3- dimensional images

Baig, M. M. J.; Wang, Y. L.; Chung, S. H.; Stepanyants, A.

10.1101/2024.01.12.574651 — bioengineering — Posted on 2024-01-15

2695 A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data

Zingaro, A.; Ahmad, Z.; Kholmovski, E.; Sakata, K.; Dede', L.; Morris, A. K.; Quarteroni, A.; Trayanova, N. A.

10.1101/2024.01.11.575156 — bioengineering — Posted on 2024-01-15

2696 Revealing Early Spatial Patterns of Cellular Responsivity in Fiber-Reinforced Microenvironments

Pucha, S. A.; Hasson, M.; Solomon, H.; McColgan, G. E.; Robinson, J. L.; Vega, S. L.; Patel, J. M.

10.1101/2024.01.12.575366 — bioengineering — Posted on 2024-01-15

2697 A meta-analysis of the relationship between color and aggression

Ruckman, S. N.; Humphrey, E. A.; Muzzey, L.; Prantalou, I.; Pleasants, M.; Hughes, K. A.

10.1101/2024.01.12.575404 — evolutionary biology — Posted on 2024-01-15

2698 Large language models help facilitate the automated synthesis of information on potential pest controllers

Scheepens, D.; Millard, J.; Farrell, M.; Newbold, T.

10.1101/2024.01.12.575330 — ecology — Posted on 2024-01-15

2699 Gadolinium-based nanoparticles AGuIX and their combination with ionizing radiation trigger AMPK-dependent proinflammatory reprogramming of tumor-associated macrophages

Muradova, Z.; Tannous, D.; Mostefa-Kara, A.; Cao-Pham, T. T.; Lamy, C.; Broutin, S.; Paci, A.; Dufort, S.; Doussineau, T.; Lux, F.; Tillement, O.; Le Duc, G.; Allouch, A.; PERFETTINI, j.-l.

10.1101/2024.01.12.575217 — immunology — Posted on 2024-01-15

2700 Body-wide genetic deficiency of poly(ADP-ribose) polymerase 14 sensitizes mice to colitis

Vedantham, M.; Polari, L.; Poosakkannu, A.; Pinto, R. G.; Sakari, M.; Laine, J.; Sipila, P.; Maatta, J.; Gerke, H.; Rissanen, T. M.; Rantakari, P.; Toivola, D. M.; Pulliainen, A. T.

10.1101/2024.01.12.575356 — immunology — Posted on 2024-01-15

2701 An oomycete effector co-opts a host RabGAP protein to remodel pathogen interface and subvert defense-related secretion

Yuen, E. L. H.; Tumtas, Y.; Chan, L. I.; Ibrahim, T.; Evangelisti, E.; Tulin, F.; Sklenar, J.; Menke, F.; Kamoun, S.; Bubeck, D.; Schornack, S.; Bozkurt, T. O.

10.1101/2024.01.11.575225 — plant biology — Posted on 2024-01-15

2702 Metformin protects the heart against chronic intermittent hypoxia through AMPK-dependent phosphorylation of HIF-1α

Moulin, S.; Blachot-Minassian, B.; Kneppers, A.; Thomas, A.; Paradis, S.; Bultot, L.; Arnaud, C.; Pepin, J.-L.; Bertrand, L.; Mounier, R.; Belaidi, E.

10.1101/2024.01.11.575152 — physiology — Posted on 2024-01-15

2703 Decreased sarcomeric mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin action in type 2 diabetes

Rizo-Roca, D.; Guimaraes, D. S.; Pendergrast, L. A.; Di Leo, N.; Chibalin, A. V.; Maqdasy, S.; Ryden, M.; Naslund, E.; Ziearth, J. R.; Krook, A.

10.1101/2024.01.11.575194 — physiology — Posted on 2024-01-15

2704 Constitutive Photomorphogenesis Protein 1 homolog (COP1) sustains nuclear factor-4 alpha function in human hepatocyte models

Soubeyrand, S.; Lau, P.; McPherson, R.

10.1101/2024.01.11.575239 — cancer biology — Posted on 2024-01-15

2705 Repetitive Learning Control for Body Caudal Undulation with Soft Sensory Feedback

Schwab, F.; El Arayshi, M.; Rezaei, S.; Sprumont, H.; Allione, F.; Mucignat, C.; Lunati, I.; Verrelli, C. M.; Jusufi, A.

10.1101/2024.01.11.575004 — bioinformatics — Posted on 2024-01-15

2706 Discriminative histone imputation using chromatin accessibility

Wen, W.; Zhong, J.; Zhang, Z.; Chu, T.; Wang, N.; Danko, C. G.; Wang, Z.

10.1101/2024.01.11.575175 — bioinformatics — Posted on 2024-01-15

2707 Trans2express - de novo transcriptome assembly pipeline optimized for gene expression analysis

Kasianova, A. M.; Penin, A. A.; Schelkunov, M. I.; Kasianov, A. S.; Logacheva, M. D.; Klepikova, A. V.

10.1101/2024.01.11.575187 — bioinformatics — Posted on 2024-01-15

2708 Logic-based modeling of biological networks with Netflux

Clark, A. P.; Chowkwale, M.; Paap, A.; Dang, S.; Saucerman, J. J.

10.1101/2024.01.11.575227 — bioengineering — Posted on 2024-01-15

2709 Shrimp Hemocyanin elicits a potent humoral response in mammals and is favorable to hapten conjugation

Jiang, B.; Wu, J.; Sun, H.; Wei, M.; Guo, A.; Zhang, C.; Wang, Y.; Huang, R.; Li, X.; Zhan, J.

10.1101/2024.01.11.575311 — bioengineering — Posted on 2024-01-15

2710 Integration of genetic and epigenetic data pinpoints autoimmune specific remodelling of enhancer landscape in CD4+ T cells

Daga, N.; Servaas, N. H.; Kisand, K.; Moonen, D.; Arnold, C.; Reyes-Palomares, A.; Kaleviste, E.; Kingo, K.; Kuuse, R.; Ulst, K.; Steinmetz, L.; Peterson, P.; Nakic, N.; Zaugg, J. B.

10.1101/2024.01.11.575022 — genomics — Posted on 2024-01-15

2711 Computational and neural evidence for altered fast and slow learning from losses in gambling disorder

Iigaya, K.; Larsen, T.; Fong, T.; O'Doherty, J. P.

10.1101/2024.01.08.574767 — neuroscience — Posted on 2024-01-15

2712 With the leisure of time, kinetic proofreading does reliable ligand discrimination after all

Xiao, F.; Galstyan, V.

10.1101/2024.01.11.575129 — systems biology — Posted on 2024-01-15

2713 Evaluating Evapotranspiration in a Commercial Greenhouse: A Comparative Study of Microclimatic Factors and Machine-Learning Algorithms

Moshelion, M.

10.1101/2024.01.11.575151 — plant biology — Posted on 2024-01-15

2714 A centromere-derived retroelement RNA localizes in cis and is a core element of the transcriptional landscape of Drosophila centromeres

Mellone, B. G.; Santinello, B.; Sun, R.; Amjad, A.; Hoyt, S. J.; Luoxuan, O.; Courret, C.; Drennan, R.; Leo, L.; Larracuente, A. M.; Core, L. M.; O'Neill, R. J.

10.1101/2024.01.14.574223 — cell biology — Posted on 2024-01-15

2715 Venturicidin A affects the mitochondrial membrane potential and induces kDNA loss in Trypanosoma brucei

Hauser, D. A.; Kaiser, M.; Mäser, P.; Albisetti, A.

10.1101/2024.01.12.575445 — microbiology — Posted on 2024-01-15

2716 RNA polymerase III is involved in regulating Plasmodium falciparum virulence

Diffendall, G. M.; Claes, A.; Barcons-Simon, A.; Nyarko, P.; Dingli, F.; Santos, M.; Loew, D.; Claessens, A.; Scherf, A.

10.1101/2023.07.18.549525 — microbiology — Posted on 2024-01-15

2717 The role of m6A methyltransferase WTAP in inflammatory response of atherosclerosis through NF-κB/NLRP3 mediated pyroptosis

Hu, B.; He, M.; Sha, Y.; Guo, F.

10.1101/2024.01.12.575466 — immunology — Posted on 2024-01-15

2718 Dysregulated expanded endocannabinoid system as therapeutic targets of amyotrophic lateral sclerosis

Ito, D.; Iida, M.; Iguchi, Y.; Hashizume, A.; Yamada, S.; Kishimoto, Y.; Komori, S.; Shimamura, T.; Takemoto, Y.; Nakatochi, M.; Akashi, T.; Hinohara, K.; Lee-Okada, H.-C.; Niwa, J.; Sobue, G.; Tanaka, S.; Takashina, K.; Yokomizo, T.; Katsuno, M.

10.1101/2024.01.12.575341 — neuroscience — Posted on 2024-01-15

2719 Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales

Crombie, D.; Spacek, M. A.; Leibold, C.; Busse, L.

10.1101/2021.04.30.442134 — neuroscience — Posted on 2024-01-15

2720 The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress

Jansen, J.; Bohnsack, K. E.; Boehlken-Fascher, S.; Bohnsack, M. T.; Dobbelstein, M.

10.1101/2023.12.29.573614 — cancer biology — Posted on 2024-01-15

2721 A polymer physics view of peripheral chromatin: de Gennes' self-similar carpet model

Erbas, A.; Sariyer, O. S.

10.1101/2024.01.05.574343 — biophysics — Posted on 2024-01-15

2722 An Efficient Computational Method to Create Positive NIPT Samples with Autosomal Trisomy

Nguyen Huy, T.; Nguyen, H. V.; Pham, M. D.; Le, V. S.

10.1101/2023.11.24.568620 — bioinformatics — Posted on 2024-01-15

2723 Genome assembly of the milky mangrove Excoecaria agallocha

10.1101/2024.01.13.575302 — genomics — Posted on 2024-01-15

2724 A single changing hypernetwork to represent (social-)ecological dynamics

Gaucherel, C.; Cosme, M.; Nous, C.; Pommereau, F.

10.1101/2023.10.30.564699 — ecology — Posted on 2024-01-15

2725 Heritable intraspecific variation among prey in size and movement interact to shape predation risk and potential natural selection

Coblentz, K. E.; Yang, L.; Dalal, A.; Incarnato, M. M. N.; Thilakarathne, D. D.; Shaw, C.; Wilson, R.; Biagioli, F.; Montooth, K. L.; DeLong, J. P.

10.1101/2024.01.11.575285 — ecology — Posted on 2024-01-15

2726 Integrative analysis in head and neck cancer reveals distinct role of miRNome and methylome as tumour epigenetic drivers

Mandic, K.; Milutin Gasperov, N.; Bozinovic, K.; Dediol, E.; Sincic, N.; Grce, M.; Sabol, I.; Baresic, A.

10.1101/2024.01.11.575141 — molecular biology — Posted on 2024-01-15

2727 Soil health increases primary productivity across Europe

Romero, F.; Labouyrie, M.; Orgiazzi, A.; Ballabio, C.; Panagos, P.; Jones, A.; Tedersoo, L.; Bahram, M.; Smith, L. C.; Guerra, C. A.; Lugato, E.; Eisenhauer, N.; Delgado-Baquerizo, M.; van der Heijden, M. G. A.

10.1101/2023.10.29.564603 — ecology — Posted on 2024-01-15

2728 The organotypic culture of mouse seminiferous tubules as a reliable methodology for the study of meiosis in vitro

Lopez-Jimenez, P.; Berenguer, I.; Perez-Moreno, I.; G. de Aledo, J.; Parra, M. T.; Page, J.; Gomez Lencero, R.

10.1101/2023.02.03.526942 — cell biology — Posted on 2024-01-15

2729 Lateral hypothalamic GABAergic neurons encode alcohol memories.

Alonso-Lozares, I.; Wilbers, P.; Teijsse, S.; Asperl, L.; van der Neut, C.; Schetters, D.; Van Mourik, Y.; McDonald, A. J.; Heistek, T. S.; Mansvelder, H.; De Vries, T. J.; Marchant, N. J.

10.1101/2023.11.16.567157 — neuroscience — Posted on 2024-01-15

2730 PRO-LDM: Protein Sequence Generation with a Conditional Latent Diffusion Model

Zhang, S.; Jiang, Z.; Huang, R.; Mo, S.; Zhu, L.; Li, P.; Zhang, Z.; Pan, E.; Chen, X.; Long, Y.; Liang, Q.; Tang, J.; Xu, R.; Qing, R.

10.1101/2023.08.22.554145 — bioengineering — Posted on 2024-01-15

2731 Complete absence of GLUT1 does not impair human terminal erythroid differentiation

Martins Freire, C.; King, N. R.; Dzieciatkowska, M.; Stephenson, D.; Moura, P. L.; Dobbe, J. G. G.; Streekstra, G. J.; D'Alessandro, A.; Toye, A. M.; Satchwell, T. J.

10.1101/2024.01.10.574621 — cell biology — Posted on 2024-01-15

2732 The mitochondrial mRNA stabilizing protein, SLIRP, regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms

Pham, T. C. P.; Raun, S. H.; Havula, E.; Henriquez-Olguin, C.; Rubalcava-Gracia, D.; Frank, E.; Fritzen, A. M.; Jannig, P. R.; Andersen, N. R.; Kruse, R.; Ali, M.; Halling, J. F.; Ringholm, S.; Needham, E. J.; Hansen, S.; Lemminger, A. K.; Schjerling, P.; Petersen, M. H.; de Almeida, M. E.; Jensen, T. E.; Kiens, B.; Hostrup, M.; Larsen, S.; Ortenblad, N.; Hojlund, K.; Kjaer, M.; Ruas, J. L.; Trifunovic, A.; Wojtaszewski, J. F. P.; Nielsen, J.; Qvortrup, K.; Pilegaard, H.; Richter, E. A.; Sylow, L.

10.1101/2023.10.30.564600 — molecular biology — Posted on 2024-01-15

2733 Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization

Fukumoto, J.; Fukumoto, J.; Yoshida, M.; Tokuoka, S. M.; Hayakawa, E. S. H.; Miyazaki, S.; Sakura, T.; Ken Inaoka, D.; Ken Inaoka, D.; Kita, K.; Kita, K.; Usukura, J.; Shindou, H.; Shindou, H.; Tokumasu, F.; Tokumasu, F.

10.1101/2024.01.13.575495 — microbiology — Posted on 2024-01-15

2734 Cognitive Phenotype Shifts in Risk-Taking: Interplay of Non-Suicidal Self-Injury Behaviors and Intensified Depression

Lu, Y.-L.; Ge, Y.; Li, M.; Liang, S.; Zhang, X.; Sui, Y.; Yang, L.; Li, X.; Zhang, Y.; Zhang, H.; Yan, H.

10.1101/2023.12.10.570987 — neuroscience — Posted on 2024-01-15

2735 Precise 3D Localization of Intracerebral Implants with a simple Brain Clearing Method

Catanese, J.; Murakami, T.; Kenny, P. J.; Ibanez-Tallon, I.

10.1101/2023.12.22.573088 — neuroscience — Posted on 2024-01-15

2736 Response inhibition in premotor cortex correspondsto a complex reshuffle of the mesoscopic informationnetwork

Bardella, G.; Giuffrida, V.; Giarrocco, F.; Brunamonti, E.; Pani, P.; Ferraina, S.

10.1101/2021.03.15.435381 — neuroscience — Posted on 2024-01-15

2737 Agents seeking long-term access to the wisdom of the crowd reduce immediate decision-making accuracy

Mann, R. P.

10.1101/2023.09.16.558066 — animal behavior and cognition — Posted on 2024-01-15

2738 Denisovan admixture facilitated environmental adaptation in Papua New Guinean populations

Yermakovich, D.; Andre, M.; Brucato, N.; Kariwiga, J.; Leavesley, M.; Pankratov, V.; Mondal, M.; Ricaut, F.-X.; Dannemann, M.

10.1101/2024.01.14.575483 — genomics — Posted on 2024-01-14

2739 Agent-Based Modelling shows that Operation of Fisher's Principle does not explain Zero Heritability in Human Offspring Sex Ratio

Harper, K.; Sidari, M. J.; Zietsch, B. P.

10.1101/2023.04.04.535652 — evolutionary biology — Posted on 2024-01-15

2740 Methyl substituted β-lactam framework based antibiotics and β-lactamase inhibitors: Proof of concept by computations

Thakkur, V.; Das, C. K.; Verma, S.; Saha, S.; Nair, N. N.

10.1101/2024.01.14.575563 — biochemistry — Posted on 2024-01-14

2741 A novel human pluripotent stem cell-based gene activation system identifies IGFBP2 as a mediator in the production of hematopoietic progenitors in vitro

Petazzi, P.; Ventura, T.; Luongo, F. P.; McClafferty, H.; May, A.; Taylor, H. A.; Shipston, M.; Romano, N.; Forrester, L.; Menendez, P.; Fidanza, A.

10.1101/2024.01.14.575573 — cell biology — Posted on 2024-01-14

2742 Beyond microtubules: The cellular environment at the endoplasmic reticulum attracts proteins to the nucleus, enabling nuclear transport

Chae, S. J.; Kim, D. W.; Igoshin, O. A.; Lee, S.; Kim, J. K.

10.1101/2024.01.12.575351 — systems biology — Posted on 2024-01-14

2743 Genomes of Aegilops umbellulata provide new insights into unique structural variations and genetic diversity in the U-genome for wheat improvement

Singh, J.; Gudi, S.; Maughan, P. J.; Liu, Z.; Kolmer, J.; Wang, M.; Chen, X.; Rouse, M.; Lasserre-Zuber, P.; Rimbert, H.; Sehgal, S.; Fiedler, J.; Choulet, F.; Acevado, M.; Gupta, R.; Gill, U.

10.1101/2024.01.13.575480 — plant biology — Posted on 2024-01-14

2744 Stress Granule Protein TZF1 Enhances Salt Stress Tolerance by Targeting ACA11 mRNA for Degradation in Arabidopsis

He, S.-L.; Li, B.; Zahurancik, W. J.; Arthur, H. C.; Sidharthan, V.; Gopalan, V.; Wang, L.; Jang, J.-C.

10.1101/2024.01.12.575397 — plant biology — Posted on 2024-01-14

2745 The Arabidopsis thaliana TRAPPIII subunit AtTRAPPC8/AtTRS85 is involved in ER functioning and autophagy

Hoffman-Sommer, M.; Pilka, N.; Anielska-Mazur, A.; Nowakowska, J.; Dagdas, Y.; Swiezewska, E.

10.1101/2024.01.11.575191 — plant biology — Posted on 2024-01-14

2746 Genome and tissue-specific transcriptome of the tropical milkweed (Asclepias curassavica)

Feng, H.; Zhang, J.; Powell, A. F.; Buttelman, G. L.; Yang, L.; Yan, E.; Wang, F.; Broyles, S. B.; Jander, G.; Strickler, S. R.

10.1101/2024.01.12.575411 — plant biology — Posted on 2024-01-14

2747 Antibiotics affect the pharmacokinetics of n-butylphthalide in vivo by altering the intestinal microbiota

Li, X.; Guo, X.; Liu, Y.; Ren, F.; Li, S.; Yang, X.; Liu, J.; Zhang, Z.

10.1101/2024.01.12.575425 — pharmacology and toxicology — Posted on 2024-01-14

2748 Different outcomes of endurance and resistance exercise in skeletal muscles of Oculopharyngeal muscular dystrophy.

Boulinguiez, A.; Dhiab, J.; Crisol, B.; Muraine, L.; Gaut, L.; Rouxel, C.; Flaire, J.; Mouigni, H.-R.; Lemaitre, M.; Giroux, B.; Adoux, L.; SaintPierre, B.; Ferry, A.; Mouly, V.; Butler-Bowne, G. S.; Negroni, E.; Malerba, A.; Trollet, C.

10.1101/2024.01.12.575335 — pathology — Posted on 2024-01-14

2749 Eliminating the missing cone challenge through innovative approaches

Gillman, C.; Bu, G.; Danelius, E.; Hattne, J.; Nannenga, B.; Gonen, T.

10.1101/2024.01.11.575283 — biochemistry — Posted on 2024-01-14

2750 Dbp1 is a low performance paralog of RNA helicase Ded1 that drives impaired translation and heat stress response

Powers, E. N.; Reynaud, K.; Sousa, C.; Kuwayama, N.; Jovanovic, M.; Ingolia, N.; Brar, G. A.

10.1101/2024.01.12.575095 — genomics — Posted on 2024-01-14

2751 Improved Temporal and Spatial Focality of Non-invasive Deep-brain Stimulation using Multipolar Single-pulse Temporal Interference with Applications in Epilepsy

ACERBO, E.; Botzanowski, B.; Dellavale, D.; Stern, M. A.; Cole, E.; Gutekunst, C.-A.; Gantt, M.; Steiner, M.; MISSEY, F.; Cassara, A.; Neufeld, E.; Berglund, K.; Jirsa, V.; Gross, R.; Drane, D.; Glowacki, E.; Pakhomov, A.; Williamson, A.

10.1101/2024.01.11.575301 — neuroscience — Posted on 2024-01-14

2752 Targeted-Neuroinflammation Mitigation Using Inflammasome-Inhibiting Nanoligomers is Therapeutic in Experimental Autoimmune Encephalomyelitis (EAE) Mouse Model

Sharma, S.; Risen, S.; Gilberto, V.; Boland, S.; Chatterjee, A.; Moreno, J.; Nagpal, P.

10.1101/2024.01.11.575262 — neuroscience — Posted on 2024-01-14

2753 Safety and efficacy study of CRISPR/Cas9 treatment of sickle cell disease in clinically relevant conditions highlights disease-specific response

Frati, G.; Brusson, M.; Sartre, G.; MLAYAH, B.; FELIX, T.; Chalumeau, A.; Antoniou, P.; Hardouin, G.; Concordet, J.-P.; Romano, O.; Turchiano, G.; Miccio, A.

10.1101/2024.01.14.575586 — bioengineering — Posted on 2024-01-14

2754 Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin

Duncan, S. M.; Carbajo, C. G.; Nagar, R.; Zhong, Q.; Breen, C.; Ferguson, M. A.; Tiengwe, C.

10.1101/2024.01.14.575564 — molecular biology — Posted on 2024-01-14

2755 NRX-101 (D-Cycloserine + Lurasidone) , a Qualified Infectious Disease Product, is Active Against Drug-Resistant Urinary Pathogens In Vitro

Sapko, M. T.; Manyak, M.; Panicucci, R.; Javitt, J. C.

10.1101/2024.01.14.575572 — microbiology — Posted on 2024-01-14

2756 Deciphering the co-evolutionary dynamics of L2 β-lactamases via Deep learning

Zhu, Y.; Gu, J.; Zhao, Z.; Chan, A. W. E.; Mojica, M. F.; Hujer, A. M.; Bonomo, R. A.; Haider, S.

10.1101/2024.01.14.575584 — microbiology — Posted on 2024-01-14

2757 Testing microbial biomining from asteroidal material onboard the International Space Station

Santomartino, R.; Rodriguez Blanco, G.; Gudgeon, A.; Hafner, J. H.; Stirpe, A.; Waterfall, M.; Cayzer, N.; Pichevin, L.; Calder, G.; Birkenfeld, K. R.; Waajen, A. C.; McLaughlin, S.; Mariani, A.; Balsamo, M.; Neri, G.; Eades, L. J.; Cockell, C.

10.1101/2024.01.13.575412 — microbiology — Posted on 2024-01-14

2758 Biochemical characterization of the Escherichia coli surfaceome: A focus on type I fimbriae and flagella.

Kavanaugh, D. W.; Sivignon, A.; Rossez, Y.; Chouit, Z.; Chambon, C.; Beal, L.; Hebraud, M.; Guerardel, Y.; Nguyen, H.; Barnich, N.

10.1101/2024.01.14.575581 — microbiology — Posted on 2024-01-14

2759 Biology System Description Language (BiSDL): a modeling language for the design of multicellular synthetic biological systems

Giannantoni, L.; Bardini, R.; Savino, A.; Di Carlo, S.

10.1101/2024.01.13.575499 — synthetic biology — Posted on 2024-01-14

2760 The Streptococcus phage protein paratox is an intrinsically disordered protein.

Asakereh, I.; Rutbeek, N. R.; Singh, M.; Davidson, D.; Prehna, G.; Khajehpour, M.

10.1101/2024.01.14.575580 — biochemistry — Posted on 2024-01-14

2761 Examining population structure across multiple collections of Cannabis

Halpin-McCormick, A.; Heyduk, K.; Kantar, M.; Batora, N.; Masalia, R.; Law, K.; Kuntz, E.

10.1101/2022.07.09.499013 — genomics — Posted on 2024-01-14

2762 Emergence of new enhancers at late DNA replicating regions

Cornejo-Paramo, P.; Petrova, V.; Zhang, X.; Young, R.; Wong, E.

10.1101/2022.12.22.521323 — genomics — Posted on 2024-01-14

2763 Protein kinase Sut1 from the Crenarchaeon Sulfolobus acidocaldarius displays tyrosine phosphorylation activity

Maklad, H. R.; Ruys, S. P. d.; Bervoets, I.; Vertommen, D.; Gutierrez, G. J.; Vranken, W. F.; Siebers, B.; Peeters, E.

10.1101/2024.01.14.552423 — microbiology — Posted on 2024-01-14

2764 A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

Saldana-Guerrero, I. M.; Montano-Gutierrez, L. F.; Boswell, K.; Hafemeister, C.; Poon, E.; Shaw, L. E.; Stavish, D.; Lea, R. A.; Wernig-Zorc, S.; Bozsaky, E.; Fetahu, I. S.; Zoescher, P.; Pötschger, U.; Bernkopf, M.; Wenninger-Weinzierl, A.; Sturtzel, C.; Souilhol, C.; Tarelli, S.; Shoeb, M. R.; Bozatzi, P.; Rados, M.; Guarini, M.; Buri, M. C.; Weninger, W.; Putz, E. M.; Huang, M.; Ladenstein, R.; Andrews, P. W.; Barbaric, I.; Cresswell, G. D.; Bryant, H. E.; Distel, M.; Chesler, L.; Taschner-Mandl, S.; Farlik, M.; Tsakiridis, A.; Halbritter, F.

10.1101/2022.11.21.515753 — cancer biology — Posted on 2024-01-14

2765 Male contributions to female-male mutualism overcome the twofold cost of sex.

Yasui, Y.; Hasegawa, E.

10.1101/2024.01.11.575303 — evolutionary biology — Posted on 2024-01-14

2766 iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Gordillo-Sampedro, S.; Antounians, L.; Wei, W.; Mufteev, M.; Lendemeijer, B.; Kushner, S. A.; de Vrij, F.; Zani, A.; Ellis, J.

10.1101/2023.04.29.538761 — molecular biology — Posted on 2024-01-14

2767 Development of a simple and highly sensitive method for the concentration and detection of African swine fever virus in oral fluids and its feasibility assessment on raised pigs in Northern Vietnam

Mai Thi, N.; Tran Thi Huong, G.; Dong Van, H.; Le Van, P.; Huynh Thi My, L.; Bui Tran Anh, D.; Uemura, R.; Yamazaki, Y.; Nguyen Thi, L.; Yamazaki, W.

10.1101/2024.01.13.575502 — microbiology — Posted on 2024-01-14

2768 Stopping Speed in Response to Auditory and Visual Stop Signals Depends on Go Signal Modality

Weber, S.; Salomoni, S. E.; St George, R. J.; Hinder, M. R.

10.1101/2024.01.10.575126 — neuroscience — Posted on 2024-01-14

2769 Hippocampal subfield CA1-3 shows differential structural and functional network plasticity after stress-reducing socio-affective mental training

Valk, S. L.; Engert, V.; Puhlmann, L.; Linz, R.; Caldairou, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B. C.; Singer, T.

10.1101/2023.03.03.531039 — neuroscience — Posted on 2024-01-14

2770 Switching to external flows: perturbations of developing vasculature within chicken chorioallantoic membrane

Padmanaban, P.; van Galen, D.; Salehi-Nik, N.; Zakharova, M.; Segerink, L.; Rouwkema, J.

10.1101/2024.01.11.575208 — bioengineering — Posted on 2024-01-14

2771 Effects of point density on interpretability of lidar-derived forest structure metrics in two temperate forests

Swanson, C.; Merrick, T.; Abelev, A.; Liang, R.; Vermillion, M.; Buma, W.; Li, R.-R.

10.1101/2024.01.11.575266 — ecology — Posted on 2024-01-14

2772 pGpG-signaling regulates virulence and global transcriptomic targets in Erwinia amylovora

Kharadi, R. R.; Hsueh, B. Y.; Waters, C. M.; Sundin, G. W.

10.1101/2024.01.12.575434 — microbiology — Posted on 2024-01-14

2773 Antagonists of the stress and opioid systems restore the functional connectivity of the prefrontal cortex during alcohol withdrawal through divergent mechanisms.

Carrette, L. L. G.; Santos, A.; Brennan, M.; Othman, D.; Collazo, A.; George, O.

10.1101/2023.09.30.560339 — neuroscience — Posted on 2024-01-14

2774 The spatial periodic computation of hippocampus-entorhinal circuit in navigation

Zhang, B.; Liu, J.

10.1101/2022.01.29.478346 — neuroscience — Posted on 2024-01-14

2775 Conserved amino acid residues and gene expression patterns associated with the substrate preferences of the competing enzymes FLS and DFR

Choudhary, N.; Pucker, B.

10.1101/2023.11.05.565693 — plant biology — Posted on 2024-01-14

2776 Bone quality following peripubertal growth in a mouse model of transmasculine gender-affirming hormone therapy

Henry, B. W.; Dela Cruz, C.; Goulet, R. W.; Nolan, B. T.; Locke, C.; Padmanabhan, V.; Moravec, M. B.; Shikanov, A.; Killian, M. L.

10.1101/2023.12.08.570840 — physiology — Posted on 2024-01-14

2777 Development of primary osteoarthritis during aging in genetically diverse UM-HET3 mice

Poudel, S. B.; Raff, R. R.; Yildirim, G.; Miller, R.; Harrison, D.; Strong, R.; Kirsch, T.; Yakar, S.

10.1101/2023.12.16.571693 — pathology — Posted on 2024-01-14

2778 Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment

Fuller, A. M.; Pruitt, H. C.; Liu, Y.; Irizarry-Negron, V. M.; Pan, H.; Song, H.; DeVine, A.; Katti, R. S.; Devalaraja, S.; Ciotti, G. E.; Gonzalez, M.; Williams, E. F.; Murazzi, I.; Ntekoumes, D.; Skuli, N.; Hakonarson, H.; Zabransky, D. J.; Trevino, J.; Weeraratna, A.; Weber, K.; Haldar, M.; Fraietta, J. A.; Gerecht, S.; Eisinger-Mathason, T. S. K.

10.1101/2022.03.31.486627 — cancer biology — Posted on 2024-01-14

2779 Orthotopic injection of an established syngeneic mouse oral cancer cell line (MOC1) induces a robust draining lymph node response

Kansal, V.; Kinney, B. L. C.; Schmitt, N. C.

10.1101/2024.01.12.575399 — cancer biology — Posted on 2024-01-14

2780 Delineation of signaling routes that underlie differences in macrophage phenotypic states

Totu, T.; Bossart, J.; Hast, K.; Li, C.; Rottmar, M.; Sobottka, B.; Yu, G.; Ayala-Nunez, V.; Buljan, M.

10.1101/2024.01.12.574349 — bioinformatics — Posted on 2024-01-14

2781 A novel classification framework for genome-wide association study of whole brain MRI images using deep learning

Yu, S.; Wu, J.; Shao, Y.; Qiu, D.; Qin, Z.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/2024.01.11.575251 — bioinformatics — Posted on 2024-01-14

2782 Enhancing Uterine Receptivity for Embryo Implantation through Controlled Collagenase Intervention

Zehorai, E.; Gross, T.; Shimshoni, E.; Hadas, R.; Adir, I.; Golani, O.; Molodij, G.; Eitan, R.; Kadler, K.; Kollet, O.; Neeman, M.; Dakel, N.; Solomonov, I.; Sagi, I.

10.1101/2022.01.18.476712 — biochemistry — Posted on 2024-01-14

2783 Pervasive sublethal effects of agrochemicals as contributing factors to insect decline

Gandara, L.; Jacoby, R.; Laurent, F.; Spatuzzi, M.; Vlachopoulos, N.; Borst, N. O.; Ekmen, G.; Potel, C. M.; Garrido-Rodriguez, M.; Boehmert, A. L.; Misunou, N.; Bartmanski, B. J.; Li, X. C.; Kutra, D.; Heriche, J.-K.; Tischer, C.; Zimmermann-Kogadeeva, M.; Ingham, V. A.; Savitski, M.; Masson, J.-B.; Zimmermann, M.; Crocker, J.

10.1101/2024.01.12.575373 — ecology — Posted on 2024-01-14

2784 Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure

Girard-Tercieux, C.; Vieilledent, G.; Clark, A. T.; Clark, J. S.; Courbaud, B.; Fortunel, C.; Kunstler, G.; Pelissier, R.; Rueger, N.; Marechaux, I.

10.1101/2022.08.06.503032 — ecology — Posted on 2024-01-14

2785 Inhibition of Alpha Interferon-Induced miR-873 Negatively Affects the Hepatitis B Virus Expression

Zhou, M.; Liu, X.; Fan, J.; Chen, L.; Zhao, M.; Luo, J.; Li, S.; Zhou, L.

10.1101/2024.01.12.575436 — molecular biology — Posted on 2024-01-14

2786 Spatio-temporal analysis of Vaccinia virus infection and host response dynamics using single-cell transcriptomics and proteomics

Matia, A.; McCarthy, F.; Woosley, H.; Turon-Lagot, V.; Platzer, S. W.; Liu, J.; Lorenzo, M. M.; Borja, M.; Shetty, K.; Winkler, J.; Elias, J. E.; Blasco, R.; Arias, C.; Hein, M. Y.

10.1101/2024.01.13.575413 — microbiology — Posted on 2024-01-14

2787 BATF controls IFN I production via DC-SCRIPT in plasmacytoid dendritic cells

Ali, S.; Mann-Nüttel, R.; Marson, M.; Leiser, B.; Hoffe, J.; Dress, R. J.; Bhuyan, M. H.; Petzsch, P.; Köhrer, K.; Xu, H. C.; Lang, P. A.; Zhang, S.; Chopin, M.; Nutt, S. L.; Alferink, J.; Scheu, S.

10.1101/2024.01.11.574638 — immunology — Posted on 2024-01-14

2788 Immunogenicity of autologous and allogeneic human primary cholangiocyte organoids

Petrus-Reurer, S.; Tysoe, O.; Lei, W.; Mairesse, M.; Tan, T.; Rehakova, S.; Mahbubani, K.; Jones, J.; Brodie, C.; Han, N.; Betts, C.; Vallier, L.; Saeb-Parsy, K.

10.1101/2024.01.11.574744 — immunology — Posted on 2024-01-14

2789 Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens

Lam, S.; Thomas, J. C.; Jackson, S. P.

10.1101/2024.01.14.575203 — bioinformatics — Posted on 2024-01-14

2790 Genome sequence resources from three isolates of the apple canker pathogen Neonectria ditissima infecting forest trees.

Bourras, S.; Velez, H.; Corrales Gutierrez, M. A.; Elfstrand, M.; Garkava-Gustavsson, L.; Dalman Falk, K.

10.1101/2024.01.13.575195 — genomics — Posted on 2024-01-14

2791 Neutral speciation in realistic populations

Nelson, E. D.

10.1101/2024.01.10.575124 — ecology — Posted on 2024-01-14

2792 Fall of giants: European diversity resistance to waterscape degradation and its potential continental drivers

Cunillera-Montcusi, D.; Borthagaray, A.-I.; Bou, J.; Arim, M.

10.1101/2024.01.11.574179 — ecology — Posted on 2024-01-14

2793 Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

Arnold, M. R.; Cohn, G. M.; Oxe, K. C.; Elliott, S. N.; Moore, C.; Laraia, P. V.; Shekoohi, S.; Brownell, D.; Meshul, C. K.; Witt, S. N.; Larsen, D. H.; Unni, V. K.

10.1101/2024.01.13.575526 — cell biology — Posted on 2024-01-14

2794 NPAS4 is an allostatic regulator of POMC neuronal activity during diet-induced obesity

Yoon, J. S.; Gamu, D.; Gibson, W. T.; Lynn, F. C.

10.1101/2024.01.12.574247 — physiology — Posted on 2024-01-14

2795 Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration

Llanses Martinez, M.; Nan, K.; Bao, Z.; Bacchetti, R.; Yuan, S.; Tyler, J.; Le Guezennec, X.; Bard, F. A.; Rainero, E.

10.1101/2024.01.11.575153 — cancer biology — Posted on 2024-01-14

2796 Skeletal Muscle Stem Cells Modulate Niche Function in Duchenne Muscular Dystrophy through YY1-CCL5 Axis

Li, Y.; Li, C.; Sun, Q.; Chen, F.; Cheung, Y.; Zhao, Y.; Xie, T.; Chazaud, B.; Sun, H.; Wang, H.

10.1101/2024.01.13.575317 — cell biology — Posted on 2024-01-14

2797 The PCM scaffold enables RNA localization to centrosomes

Fang, J.; Tian, W.; Quintanilla, M. A.; Beach, J. R.; Lerit, D. A.

10.1101/2024.01.13.575509 — cell biology — Posted on 2024-01-14

2798 Transformation of human chondrocytes with copper-containing metal-organic biohybrids (MOBs)

Khasru, T.; McKenzie, K.; Rugg, K.; Boudreaux, S.; McMahen, K.; Uppu, N.; DeCoster, M. A.

10.1101/2024.01.12.575456 — cell biology — Posted on 2024-01-14

2799 Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron

Porter, A.; Vorndran, H. E.; Marciszyn, A. L.; Mutchler, S. M.; Subramanya, A. R.; Kleyman, T. R.; Hendershot, L. M.; Brodsky, J. L.; Buck, T. M.

10.1101/2024.01.13.575426 — cell biology — Posted on 2024-01-14

2800 Concurrent response and action effect representations across the somatomotor cortices during novel task preparation.

Palenciano, A. F.; Gonzalez-Garcia, C.; De Houwer, J.; Liefooghe, B.; Brass, M.

10.1101/2023.10.30.564708 — neuroscience — Posted on 2024-01-14

2801 Identifying Patient-Specific Root Causal Genes with High Throughput Perturbations

Strobl, E. V.; Gamazon, E. R.

10.1101/2024.01.13.574491 — genomics — Posted on 2024-01-14

2802 DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Mullen, N. J.; Shukla, S. K.; Thakur, R.; Kollala, S. S.; Wang, D.; Chaika, N.; Santana, J. F.; Miklavcic, W. R.; LaBreck, D. A.; Mallareddy, J. R.; Price, D.; Natarajan, A.; Mehla, K.; Sykes, D. B.; Hollingsworth, M. A.; Singh, P. K.

10.1101/2023.04.03.535399 — cancer biology — Posted on 2024-01-13

2803 Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

Davis, S. N.; Grindel, S. H.; Viola, J. M.; Liu, G. Y.; Liu, J.; Qian, G.; Porter, C. M.; Hughes, A. J.

10.1101/2023.11.21.568157 — developmental biology — Posted on 2024-01-14

2804 FoxO transcription factors actuate the formative pluripotency specific gene expression programme

Santini, L.; Kowald, S.; Sestini, G.; Rivron, N. C.; Leeb, M.

10.1101/2024.01.13.575494 — developmental biology — Posted on 2024-01-14

2805 Dyrk1a is required for craniofacial development in Xenopus laevis.

Dickinson, A. J. G.; Wahl, S. E.; Litovchick, L.; Sesay, F.; Johnson, H. K.

10.1101/2024.01.13.575394 — developmental biology — Posted on 2024-01-14

2806 The lateral habenula integrates age and experience to promote social transitions in developing rats

Cobb-Lewis, D. E.; George, A.; Hu, S.; Packard, K.; Song, M.; Nguyen-Lopez, O.; Tesone, E. I.; Rowden, J.; Wang, J.; Opendak, M.

10.1101/2024.01.12.575446 — neuroscience — Posted on 2024-01-14

2807 Modeling the impact of neuromorphological alterations in Down syndrome on fast neural oscillations

Clusella, P.; Manubens-Gil, L.; Garcia-Ojalvo, J.; Dierssen, M.

10.1101/2024.01.13.575481 — neuroscience — Posted on 2024-01-14

2808 Forget and Forgive: A Neurocognitive Mechanism for Increased Cooperation During Group Formation

Zajkowski, W. K.; Badman, R.; Haruno, M.; Akaishi, R.

10.1101/2024.01.13.572916 — neuroscience — Posted on 2024-01-14

2809 Long-Term Potentiation Produces a Sustained Expansion of Synaptic Information Storage Capacity in Adult Rat Hippocampus

Samavat, M.; Bartol, T. M.; Bromer, C.; Hubbard, D. D.; Hanka, D. C.; Kuwajima, M.; Mendenhall, J. M.; Parker, P. H.; Bowden, J. B.; Abraham, W.; Sejnowski, T. J.; Harris, K. M.

10.1101/2024.01.12.574766 — neuroscience — Posted on 2024-01-14

2810 Lactate Dynamics in Skin Interstitial Fluid Predicts Lactate Threshold in Exercising Rats

Dobashi, S.; Funabashi, D.; Sameshima, K.; Tsuruoka, N.; Matsui, T.

10.1101/2023.10.23.563585 — physiology — Posted on 2024-01-14

2811 "Two-Birds-One-Stone" Oral Nanotherapeutic Designed to Target Intestinal Integrins and Regulate Redox Homeostasis for Ulcerative Colitis Treatment

Huang, L.; Hu, W.; Huang, L. Q.; Zhou, Q. X.; Song, Z. Y.; Tao, H. Y.; Xu, B.; Zhang, C. Y.; Wang, Y.; Xing, X.-H.

10.1101/2024.01.02.573980 — bioengineering — Posted on 2024-01-14

2812 Acute Vigorous Exercise Decreases Subsequent Non-Exercise Physical Activity and Body Temperature Linked to Weight Gain

Funabashi, D.; Dobashi, S.; Sameshima, K.; Sagayama, H.; Nishijima, T.; Matsui, T.

10.1101/2023.10.25.563892 — animal behavior and cognition — Posted on 2024-01-13

2813 In vitro visualization of osteo-adipogenic lineage choice of bone marrow stromal/stem cells (BMSCs)

Qiu, D.; Wei, W.; Chen, J.; Huang, J.; Yang, Y.; Luo, Z.

10.1101/2024.01.05.574292 — cell biology — Posted on 2024-01-14

2814 Adenomatous polyposis coli (APC) regulates internalization and signaling of the chemorepellent receptor, Roundabout (ROBO) 1

Huang, Y.-W.; St-Germain, J.; Pang, B. W.; Collins, R. F.; Coyaud, E.; Li, W.; Mohamed, A.; Raught, B.; Grinstein, S.; Robinson, L. A.

10.1101/2024.01.12.574717 — cell biology — Posted on 2024-01-14

2815 Comparative Analysis of Multiple Consensus Genomes of the Same Strain of Marek's Disease Virus Reveals Intrastrain Variation

Ortigas-Vasquez, A.; Pandey, U.; Renner, D. W.; Bowen, C. D.; Baigent, S. J.; Dunn, J.; Cheng, H.; Yao, Y.; Read, A. F.; Nair, V.; Kennedy, D. A.; Szpara, M. L.

10.1101/2023.09.04.556264 — microbiology — Posted on 2024-01-14

2816 Simple Human Response Times are Governed by Dual Anticipatory Processes with Distinct and Distributed Neural Signatures

Ramayya, A. G.; Buch, V.; Richardson, A.; Lucas, T.; Gold, J. I.

10.1101/2022.06.13.496029 — neuroscience — Posted on 2024-01-13

2817 Simultaneous identification of m6A and m5C reveals coordinated RNA modification at single-molecule resolution

Acera Mateos, P.; Sethi, A. J.; Ravindran, A.; Srivastava, A.; Kanchi, M.; Mahmud, S.; Guarnacci, M.; Woodward, K.; Xu, J.; Yuen, Z. W.-S.; Zhou, Y.; Sneddon, A.; Hamilton, W.; Gao, J.; Starrs, L. M.; Hayashi, R.; Wickramasinghe, V. O.; Zarnack, K.; Preiss, T.; Burgio, G.; Dehorter, N.; Shirokikh, N. E.; Eyras, E.

10.1101/2022.03.14.484124 — bioinformatics — Posted on 2024-01-13

2818 A long-context language model for the generation of bacteriophage genomes

Shao, B.

10.1101/2023.12.18.572218 — bioinformatics — Posted on 2024-01-13

2819 Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli

Jojoa Cruz, S.; Dubin, A. E.; Lee, W.-H.; Ward, A. B.

10.1101/2023.10.03.560740 — biochemistry — Posted on 2024-01-13

2820 Investigating the molecular basis of cleptobiosis in eusocial stingless bees (Apidae: Hymenoptera)

Ricardo, P. C.; Araujo, N. d. S.; Arias, M. C.

10.1101/2024.01.12.575469 — genomics — Posted on 2024-01-13

2821 Chromosome-level de novo genome unveils the evolution of Gleditsia sinensis and thorns development

Xiao, D.; Liu, J.; Wang, J.; Yang, Y.; Yang, X.; Yu, R.; Wang, C.; Wang, Y.; Liu, Y.; Fan, D.; Lin, F.

10.1101/2024.01.11.575261 — genomics — Posted on 2024-01-13

2822 Mitochondrial membrane potential regulates nuclear DNA methylation and gene expression through phospholipid remodeling

Mori, M. P.; Lozoya, O.; Brooks, A.; Grenet, D.; Nadalutti, C.; Ryback, B.; Huang, K.-T.; Hasan, P.; Hajnoczky, G.; Santos, J.

10.1101/2024.01.12.575075 — genomics — Posted on 2024-01-13

2823 Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism

Nshanian, M.; Geller, B. S.; Gruber, J. J.; Chleilat, F.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.

10.1101/2024.01.11.575111 — genetics — Posted on 2024-01-13

2824 Little evidence for inbreeding depression for birth mass, survival and growth in Antarctic fur seal pups

Paijmans, A. J.; Berthelsen, A. L.; Nagel, R.; Christaller, F.; Kroecker, N.; Forcada, J.; Hoffman, J. I.

10.1101/2024.01.12.575355 — evolutionary biology — Posted on 2024-01-13

2825 Identification and quantification of human relaxin proteins by immunoaffinity-mass spectrometry

Rais, Y.; Drabovich, A. P.

10.1101/2024.01.12.575440 — biochemistry — Posted on 2024-01-13

2826 Identification of extracellular membrane protein ENPP3 as a major cGAMP hydrolase, cementing cGAMP's role as an immunotransmitter

Mardjuki, R.; Wang, S.; Carozza, J.; Abhiraman, G.; Lyu, X.; Li, L.

10.1101/2024.01.12.575449 — biochemistry — Posted on 2024-01-13

2827 Genomic database furnishes a spontaneous example of a functional Class II glycyl-tRNA synthetase urzyme

Patra, S. K.; Douglas, J.; Wills, P. R.; Bouckaert, R.; Betts, L.; Tang, G. Q.; carter, c. W.

10.1101/2024.01.11.575260 — evolutionary biology — Posted on 2024-01-13

2828 Endoplasmic reticulum stress delays choroid development in the HCAR1 knock-out mouse

Modaresinejad, M.; Yang, X.; Mohammad Nezhady, M. A.; Zhu, T.; Bajon, E.; Hou, X.; Tahiri, H.; Hardy, P.; Rivera, J. C.; Lachapelle, P.; Chemtob, S.

10.1101/2024.01.12.575419 — cell biology — Posted on 2024-01-13

2829 KAT5 Acetylates Human Chromatin Protein PC4 to promote DNA Repair

kundu, T. K.; Agrawal, A.; Sikder, S.; Singh, S.; Peraman, R.; Ravichandran, V.

10.1101/2024.01.12.575390 — molecular biology — Posted on 2024-01-13

2830 Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs

Gadgil, R. Y.; Rider, S. D.; Shrestha, R.; Alhawach, V.; Hitch, D.; Leffak, M.

10.1101/2024.01.12.575055 — molecular biology — Posted on 2024-01-13

2831 Intestinal stearoyl-CoA desaturase-1 regulates energy balance via alterations in bile acid homeostasis

Burchat, N.; Vidola, J.; Pfreundschuh, S.; Sharma, P.; Rizzolo, D.; Guo, G. L.; Sampath, H.

10.1101/2024.01.12.575400 — molecular biology — Posted on 2024-01-13

2832 Intrinsically disordered regions regulate RhlE RNA helicase functions in bacteria

Hausmann, S.; Geiser, J.; Allen, G. E.; Geslain, S. A. M.; Valentini, M.

10.1101/2024.01.12.575364 — molecular biology — Posted on 2024-01-13

2833 Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization

Fukumoto, J.; Yoshida, M.; Tokuoka, S. M.; Hayakawa, E. S. H.; Miyazaki, S.; Sakura, T.; Ken Inaoka, D.; Kita, K.; Usukura, J.; Shindou, H.; Tokumasu, F.

10.1101/2024.01.13.575495 — microbiology — Posted on 2024-01-13

2834 Contribution of parasite and host genotype to immunopathology of schistosome infections

Jutzeler, K. S.; Le Clec'h, W.; Chevalier, F. D.; Anderson, T. J.

10.1101/2024.01.12.574230 — microbiology — Posted on 2024-01-13

2835 Different metabolite profiles across Penicillium roqueforti populations associated with ecological niche specialisation and domestication

Crequer, E.; COTON, E.; Cueff, G.; Cristiansen, J. V.; Frisvad, J. C.; Rodriguez de la Vega, R.; Giraud, T.; Jany, J.-L.; Coton, M.

10.1101/2024.01.12.575369 — microbiology — Posted on 2024-01-13

2836 Divisome minimization shows that FtsZ and SepF can form an active Z-ring, and reveals BraB as a new cell division influencing protein in Bacillus subtilis

Celik Gulsoy, I.; Saaki, T.; Wenzel, M.; Syvertsson, S.; Morimoto, T.; Hamoen, L. W.

10.1101/2024.01.12.575403 — microbiology — Posted on 2024-01-13

2837 Droplet microfluidics for time-resolved serial crystallography

Stubbs, J.; Hornsey, T.; Hanrahan, N.; Blay-Esteban, L.; Bolton, R.; Maly, M.; Basu, S.; Orlans, J.; de Sanctis, D.; Shim, J.-u.; Shaw Stewart, P. D.; Orville, A. M.; Tews, I.; West, J.

10.1101/2024.01.12.575388 — biochemistry — Posted on 2024-01-13

2838 A cGAS-mediated IFN-I response in human CD4+ T cells depends on productive infection and is conserved over HIV types and strains

Janevska, M.; Cammaert, T.; Naessens, E.; Verhasselt, B.

10.1101/2024.01.12.575325 — microbiology — Posted on 2024-01-13

2839 Generative artificial intelligence performs rudimentary structural biology modelling

Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.

10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-01-13

2840 Coherent olfactory bulb gamma oscillations arise from coupling independent columnar oscillators

Peace, S. T.; Johnson, B. C.; Werth, J. C.; Li, G.; Kaiser, M. E.; Fukunaga, I.; Schaefer, A. T.; Molnar, A. C.; Cleland, T. A.

10.1101/213827 — neuroscience — Posted on 2024-01-13

2841 Highly divergent and diverse viral community infecting sylvatic mosquitoes from Northeast Brazil

da Silva, A. F.; Machado, L. C.; da Silva, L. M. I.; Dezordi, F. Z.; Wallau, G. d. L.

10.1101/2023.06.27.546706 — genomics — Posted on 2024-01-13

2842 Annelid methylomes reveal ancestral developmental and ageing-associated epigenetic erosion across Bilateria

Guynes, K.; Sarre, L. A.; Carrillo-Baltodano, A. M.; Davies, B. E.; Xu, L.; Liang, Y.; Martin-Zamora, F. M.; Hurd, P. J.; de Mendoza, A.; Martin-Duran, J. M.

10.1101/2023.12.21.572802 — genomics — Posted on 2024-01-13

2843 Comparative genomics of Cryptococcus and Kwoniella reveals pathogenesis evolution and contrasting karyotype dynamics via intercentromeric recombination or chromosome fusion

Coelho, M. A.; David-Palma, M.; Shea, T.; Bowers, K.; McGinley-Smith, S.; Mohammad, A. W.; Gnirke, A.; Yurkov, A. M.; Nowrousian, M.; Sun, S.; Cuomo, C. A.; Heitman, J.

10.1101/2023.12.27.573464 — genomics — Posted on 2024-01-13

2844 The evolution of fitness during range expansions in multiple dimensions

Kotsar, Y.; Matsuoka, H.; Tamiya, G.

10.1101/2023.12.29.573608 — genetics — Posted on 2024-01-13

2845 Transcriptomic Response to Nitrogen Availability Highlights Signatures of Adaptive Plasticity During Tetraploid Wheat Domestication

Pieri, A.; Beleggia, R.; Gioia, T.; Tong, H.; Di Vittori, V.; Frascarelli, G.; Bitocchi, E.; Nanni, L.; Bellucci, E.; Fiorani, F.; Pecchioni, N.; Marzario, S.; De Quattro, C.; Limongi, A. R.; De Vita, P.; Rossato, M.; Schurr, U.; David, J.; Nikoloski, Z.; Papa, R.

10.1101/2023.08.31.555682 — genetics — Posted on 2024-01-13

2846 Effects of Food Supplementation and Helminth Removal on Space Use and Spatial Overlap in Wild Rodent Populations

Mistrick, J.; Veitch, J. S. M.; Kitchen, S. M.; Clague, S.; Newman, B. C.; Hall, R. J.; Budischak, S. A.; Forbes, K. M.; Craft, M. E.

10.1101/2022.12.22.521674 — ecology — Posted on 2024-01-13

2847 Human telomere length is chromosome specific and conserved across individuals

Karimian, K.; Groot, A.; Huso, V.; Kahidi, R.; Tan, K.-T.; Sholes, S.; Keener, R. W.; McDyer, J. F.; Alder, J. K.; Li, H. K.; Rechtsteiner, A.; Greider, C. W.

10.1101/2023.12.21.572870 — molecular biology — Posted on 2024-01-13

2848 Characterization and genomic analysis of the Lyme disease spirochete bacteriophage phiBB-1

Faith, D. R.; Kinnersley, M.; Brooks, D. M.; Drecktrah, D.; Hall, L. S.; Luo, E.; Santiago-Frangos, A.; Wachter, J.; Samuels, S.; Secor, P. R.

10.1101/2024.01.08.574763 — microbiology — Posted on 2024-01-13

2849 An integrated approach to identify sex-specific genes, transcription factors, and pathways in Alzheimer's disease

Lopez-Cerdan, A.; Andreu, Z.; Hidalgo, M. R.; Porlan, A.; Pozo-Morales, M.; Leon, S.; de la Iglesia-Vaya, M.; Mikozami, A.; Guerini, F. R.; Garcia-Garcia, F.

10.1101/2023.09.05.556293 — neuroscience — Posted on 2024-01-13

2850 Somatosensory cortical representations of assimilation effect by vibrotactile stimulation

Kim, J.-H.; Jung, D.; Kim, J.; Kim, S.-P.

10.1101/2023.08.27.555001 — neuroscience — Posted on 2024-01-13

2851 A Rapid in vivo Pipeline to Identify Small Molecule Inhibitors of Amyloid Aggregation

Kamal, M.; Knox, J.; Horne, R. I.; Tiwari, O. S.; Burns, A.; Han, D.; Bar-Yosef, D. L.; Gazit, E.; Nguyen, K. C.; Hall, D. H.; Vendruscolo, M.; Roy, P. J.

10.1101/2022.04.11.487937 — pharmacology and toxicology — Posted on 2024-01-13

2852 Automated behavioral analysis reveals that mice employ a bait-and-switch escape mechanism to de-escalate social conflict.

Clein, R.; Warren, M.; Neunuebel, J. P.

10.1101/2024.01.12.575321 — animal behavior and cognition — Posted on 2024-01-13

2853 Picturing plant biodiversity from airborne environmental DNA.

Thuillet, A.-C.; Morisot, D.; Renno, J.-F.; Scarcelli, N.; Serret, J.; Mariac, C.

10.1101/2024.01.11.571706 — genetics — Posted on 2024-01-13

2854 Klebsiella pneumoniae exhibiting a phenotypic hyper-splitting phenomenon including the formation of small colony variants

Dogan, E.; Sydow, K.; Heiden, S. E.; Eger, E.; Wassilew, G.; Proctor, R. A.; Bohnert, J.; Idelevich, E. A.; Schaufler, K.; Becker, K.

10.1101/2024.01.11.575232 — microbiology — Posted on 2024-01-13

2855 Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides

King, H. R.; Bycroft, M.; Nguyen, T.-B.; Kelly, G.; Vinogradov, A. A.; Rowling, P. J.; Stott, K.; Ascher, D. B.; Suga, H.; Itzhaki, L. S.; Artavanis-Tsakonas, K.

10.1101/2024.01.11.575158 — biophysics — Posted on 2024-01-13

2856 Recurrent Evolutionary Innovations in Rodent and Primate Schlafen Genes

Mordier, J.; Fraisse, M.; Cohen-Tannoudji, M.; Molaro, A.

10.1101/2024.01.12.575368 — evolutionary biology — Posted on 2024-01-13

2857 The relationship between gut and nasopharyngeal microbiome composition can predict the severity of COVID-19

Martin-Castano, B.; Diez-Echave, P.; Garcia-Garcia, J.; Hidalgo-Garcia, L.; Ruiz-Malagon, A. J.; Molina-Tijeras, J. A.; Rodriguez-Sojo, M. J.; Redruello-Romero, A.; Martinez-Zaldivar, M.; Mota, E.; Cobo, F.; Diaz-Villamarin, X.; Fernandez-Varon, E.; Alvarez-Estevez, M.; Garcia, F.; Morales-Garcia, C.; Merlos, S.; Garcia-Flores, P.; Colmenero-Ruiz, M.; Ruiz-Sancho, A.; Nunez, M.; Rodriguez-Cabezas, M. E.; Carazo, A.; Martin, J.; Moron, R.; Rodriguez, A.; Galvez, J.

10.1101/2024.01.11.575201 — microbiology — Posted on 2024-01-13

2858 Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer's disease

Michaud, F.; Francavilla, R.; Topolnik, D.; Iloun, P.; Tamboli, S.; Calon, F.; Topolnik, L.

10.1101/2024.01.12.575331 — neuroscience — Posted on 2024-01-13

2859 The fnr-like mutants enhance isoxaben tolerance by initiating mitochondrial retrograde signalling

Broad, R.; Ogden, M.; Dracatos, P. M.; Whelan, J. M.; Persson, S.; Khan, G. A.

10.1101/2024.01.11.575284 — plant biology — Posted on 2024-01-13

2860 Human Soluble Prorenin Receptor Expressed in Adipose Tissue Improves Insulin Sensitivity and Endothelial Function in Obese Female Mice

Arthur, G.; Ahmed, N.; Nichols, K.; Poupeau, A.; Collins, K.; Lindner, V.; Loria, A. S.

10.1101/2024.01.12.575451 — physiology — Posted on 2024-01-13

2861 Polar accumulation of pyoverdin and exit from stationary phase

Moreno-Fenoll, C.; Ardre, M.; Rainey, P. B.

10.1101/2021.07.27.453990 — microbiology — Posted on 2024-01-13

2862 The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway

Chen, H.; Ferguson, C. J.; Mitchell, D. C.; Titus, A.; Paulo, J. A.; Hwang, A.; Lin, T.-H.; Yano, H.; Gu, W.; Song, S.-K.; Yuede, C. M.; Gygi, S. P.; Bonni, A.; Kim, A. H.

10.1101/2023.10.24.563880 — neuroscience — Posted on 2024-01-13

2863 Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment

Raabe, F.; Hausruckinger, A.; Gagliardi, M.; Ahmad, R.; Almeida, V.; Galinski, S.; Hoffmann, A.; Weigert, L.; Rummel, C.; Murek, V.; Trastulla, L.; Barron, L.; Atella, A.; Maidl, S.; Menegaz, D.; Hauger, B.; Wagner, E.-M.; Gabellini, N.; Kauschat, B.; Riccardo, S.; Cesana, M.; Papiol, S.; Sportelli, V.; Haffner, M.; Stolte, S.; Wehr, M.; Salcedo, T.; Papazova, I.; Wadleigh, S.; McMahon, F.; Schmitt, A.; Falkai, P.; Hasan, A.; Cacchiarelli, D.; Dannlowski, U.; Nenadi, I.; Kircher, T.; Scheuss, V.; Eder, M.; Binder, E.; Spengler, D.; Rossner, M. J.; Ziller, M. J.

10.1101/2024.01.09.574815 — neuroscience — Posted on 2024-01-13

2864 How smart was T. rex? Testing claims of exceptional cognition in dinosaurs and the application of neuron count estimates in palaeontological research

Caspar, K. R.; Gutierrez-Ibanez, C.; Bertrand, O. C.; Carr, T.; Colbourne, J.; Erb, A.; George, H.; Holtz, T. R.; Naish, D.; Wylie, D. R.; Hurlburt, G. R.

10.1101/2024.01.10.575006 — zoology — Posted on 2024-01-13

2865 Linear indexing for all strings under all internal nodes in suffix trees

Al-okaily, A.; Tbakhi, A.

10.1101/2021.10.25.465764 — bioinformatics — Posted on 2024-01-13

2866 MetaFun: Unveiling sex differences in multiple omics studies through comprehensive functional meta-analysis

Malmierca-Merlo, P.; Sanchez-Garcia, R.; Grillo-Risco, R.; Perez-Diez, I.; Catala-Senent, J. F.; Leon, S.; Gomez-Martinez, H.; de la Iglesia-Vaya, M.; Hidalgo, M. R.; Garcia-Garcia, F.

10.1101/2021.07.13.451905 — bioinformatics — Posted on 2024-01-13

2867 Calcineurin contributes to RNAi-mediated transgene silencing and small interfering RNA production in the human fungal pathogen Cryptococcus neoformans

Yadav, V.; Mohan, R.; Sun, S.; Heitman, J.

10.1101/2023.07.25.550548 — genetics — Posted on 2024-01-13

2868 Assessing the potential of germplasm collections for the management of genetic diversity: the case of the French National Cryobank

Jacques, A.; Duclos, D.; Danchin-Burge, C.; Mercat, M.-J.; Tixier-Boichard, M.; Restoux, G.

10.1101/2023.07.19.549644 — genetics — Posted on 2024-01-13

2869 Polygenic architecture of flowering time and its relationship with local environments in the grass Brachypodium distachyon.

Minadakis, N.; Kaderli, L.; Horvath, R.; Xu, W.; Thieme, M.; Woods, D. P.; Roulin, A. C.

10.1101/2023.07.11.548268 — evolutionary biology — Posted on 2024-01-13

2870 Between a Warm Winter and a Cold Spell: Physiological Responses to Changing Winter Climate in Amphibians

Schmidt, R.; Zummach, C.; Sinai, N.; Sabino-Pinto, J.; Kuenzel, S.; Dausmann, K. H.; Ruthsatz, K.

10.1101/2024.01.03.574103 — ecology — Posted on 2024-01-13

2871 A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology

Kesapragada, M.; Sun, Y.-H.; Recendez, C.; Fregoso, D.; Rolandi, M.; Yang, H.-y.; Isseroff, R. R.; Zhao, M.; Gomez, M.

10.1101/2022.11.29.518400 — cell biology — Posted on 2024-01-13

2872 The disruption of CtBP regulates DUX-dependent and -independent genetic program for the 2-cell-like state in murine embryonic stem cells

Sugiyama, K.; Yoshioka, K.; Hayakawa, N.; Marutani, M.; Masuda, R.; Abadi, S. A.; Seki, Y.

10.1101/2024.01.12.575352 — cell biology — Posted on 2024-01-13

2873 Discovery of a multipotent cell type from the term human placenta

Vadakke-Madathil, S.; Wang, B.; Oniskey, M.; Dekio, F.; Brody, R.; Gelber, S.; Sperling, R.; Chaudhry, H. W.

10.1101/2023.08.02.551028 — cell biology — Posted on 2024-01-13

2874 The apparent loss of PRC2 chromatin occupancy as an artefact of RNA depletion

Healy, E.; Zhang, Q.; Gail, E. H.; Agius, S. C.; Sun, G.; Bullen, M.; Pandey, V.; Das, P. P.; Polo, J. M.; Davidovich, C.

10.1101/2023.08.16.553488 — molecular biology — Posted on 2024-01-13

2875 Perisomatic Features Enable Efficient and Dataset Wide Cell-Type Classifications Across Large-Scale Electron Microscopy Volumes

Elabbady, L.; Seshamani, S.; Mu, S.; Mahalingam, G.; Schneider-Mizell, C. M.; Bodor, A.; Bae, J. A.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Dorkenwald, S.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mitchell, E.; Mondal, S. S.; Nehoran, B.; Popovych, S.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yin, W.; Yu, S.-c.; The MICrONS Consortium, ; Seung, H. S.; Reid, R. C.; Macarico da Costa, N.; Collman, F.

10.1101/2022.07.20.499976 — neuroscience — Posted on 2024-01-13

2876 Community-based Reconstruction and Simulation of a Full-scale Model of Region CA1 of Rat Hippocampus

Romani, A.; Antonietti, A.; Bella, D.; Budd, J.; Giacalone, E.; Kurban, K.; Saray, S.; Abdellah, M.; Arnaudon, A.; Boci, E.; Colangelo, C.; Courcol, J.-D.; Delemontex, T.; Ecker, A.; Falck, J.; Favreau, C.; Gevaert, M.; Hernando, J. B.; Herttuainen, J.; Ivaska, G.; Kanari, L.; Kaufmann, A.-K.; King, J. G.; Kumbhar, P.; Lange, S.; Lu, H.; Lupascu, C. A.; Migliore, R.; Petitjean, F.; Planas, J.; Rai, P.; Ramaswamy, S.; Reimann, M. W.; Riquelme, J. L.; Guerrero, N. R.; Shi, Y.; Sood, V.; Sy, M. F.; Van Geit, W.; Vanherpe, L.; Freund, T.; Mercer, A.; Muller, E.; Schurmann, F.; Thomson, A. M.; Migl

10.1101/2023.05.17.541167 — neuroscience — Posted on 2024-01-13

2877 Castration Model Illuminates Sex Differences in Healthy Aging: Insights from Metabolome and Transcriptome Analyses

Jiang, J.; Ge, N.; Wang, Y.; Qi, J.; Wen, G.; Gu, X.; Yu, X.; Shao, M.; Luo, Y.; Gu, K.; Lin, F.; Yang, S.; Wei, W.

10.1101/2023.12.27.573488 — systems biology — Posted on 2024-01-13

2878 Age-linked lung pathology is reduced by immunotherapeutic targeting of isoDGR protein damage

Kalailingam, P.; Mohd-Kahliab, K.-H.; SoFong Cam Ngan, S. C. N.; Iyappan, R.; Lee, B. S. T.; Bhargy Sharma, B. S.; Machan, R.; Bo, S. T.; Chambers, E. S.; Fajardo, V. A.; Macpherson, R. E. K.; Liu, J.; Klentrou, P.; Tsiani, E. L.; Lim, K. L.; Su, I. H.; Gao, Y.-G.; Richard, A. M.; Kalaria, R. N.; Chen, C. P.; McCarthy, N. E.; Sze, S. K.

10.1101/2023.08.11.552994 — pathology — Posted on 2024-01-13

2879 Agent-based modeling of nuclear chromosome ensemble identifies determinants of homolog pairing during meiosis

Chriss, A.; Boerner, G. V.; Ryan, S. D.

10.1101/2023.08.09.552574 — biophysics — Posted on 2024-01-13

2880 Conformational dynamics of a nicotinic receptor neurotransmitter binding site

Singh, M.; Indurthi, D. C.; Mittal, L.; Auerbach, A.; Asthana, S.

10.1101/2023.09.16.558050 — biophysics — Posted on 2024-01-13

2881 Simplest Model of Nervous System. I. Formalism

Sinitskiy, A. V.

10.1101/2023.11.23.568481 — biophysics — Posted on 2024-01-13

2882 Structure-function relationships of mucociliary clearance in the human airways

Roth, D.; Sahin, A. T.; Ling, F.; Senger, C.; Quiroz, E.; Calvert, B.; van der Does, A.; Güney, T. G.; Tepho, N.; Glasl, S.; van Schadewijk, A.; von Schledorn, L.; Olmer, R.; Kanso, E.; Nawroth, J. C.; Ryan, A. L.

10.1101/2023.12.24.572054 — biophysics — Posted on 2024-01-13

2883 Water will find its way: transport through narrow tunnels in hydrolases

Sequeiros-Borja, C.; Thirunavukarasu, A. S.; Dongmo Foumthuim, C. J.; Brezovsky, J.

10.1101/2023.05.24.542065 — bioinformatics — Posted on 2024-01-13

2884 Processing UMI Datasets at High Accuracy and Efficiency with the Sentieon ctDNA Analysis Pipeline

Hu, J.; Jiang, C.; Huang, Y. S.; Chen, H.; Feng, H.; Freed, D.; Qu, Y.; Fan, R.; Su, Z.; Chen, W.

10.1101/2022.06.03.494742 — bioinformatics — Posted on 2024-01-13

2885 Uncovering Interpretable Fine-Grained Phenotypes of Subcellular Dynamics through Unsupervised Self-Training of Deep Neural Networks

Wang, C.; Choi, H. J.; Woodbury, L.; Lee, K.

10.1101/2021.05.25.445699 — bioinformatics — Posted on 2024-01-13

2886 Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter.

Mumford, T. R.; Rae, D.; Brackhahn, E.; Idris, A.; Gonzalez-Martinez, D.; Pal, A. A.; Chung, M. C.; Guan, J.; Rhoades, E.; Bugaj, L. J.

10.1101/2022.07.13.499962 — bioengineering — Posted on 2024-01-13

2887 Lytic/Lysogenic Transition as a Life-History Switch

Roughgarden, J.

10.1101/2023.01.03.522622 — evolutionary biology — Posted on 2024-01-13

2888 Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease

Chen, Y.-C.; Maupas, A.; Nowick, K.

10.1101/2023.12.18.569574 — evolutionary biology — Posted on 2024-01-13

2889 Attracting pollinators vs escaping herbivores: eco-evolutionary dynamics of plants confronted with an ecological trade-off

Yacine, Y.; Loeuille, N.

10.1101/2021.12.02.470900 — ecology — Posted on 2024-01-13

2890 Functional analysis of chromatin-associated proteins in Sordaria macrospora reveals similar roles for RTT109 and ASF1 in development and DNA damage response

Breuer, J.; Ferreira, D. E. A.; Kramer, M.; Bollermann, J.; Nowrousian, M.

10.1101/2023.10.17.562778 — molecular biology — Posted on 2024-01-13

2891 Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection

Gewirtz, A. T.; Ngo, V.; Lieber, C.; Plemper, R. K.; Sakomoto, K.; Kuczma, M. P.; Kang, H.-j.

10.1101/2023.09.21.558814 — immunology — Posted on 2024-01-13

2892 Medial entorhinal cortex plays a specialized role in learning of flexible, context-dependent interval timing behavior

Bigus, E. R.; Lee, H.-W.; Bowler, J. C.; Shi, J.; Heys, J. G.

10.1101/2023.01.18.524598 — neuroscience — Posted on 2024-01-13

2893 Reliance on Episodic vs. Procedural Systems in Decision-Making Depends on Individual Differences in Their Relative Neural Efficiency

Yang, Y. C.; Sibert, C.; Stocco, A.

10.1101/2023.01.10.523458 — neuroscience — Posted on 2024-01-13

2894 A unifying account of replay as context-driven memory reactivation

Zhou, Z.; Kahana, M. J.; Schapiro, A. C.

10.1101/2023.03.22.533833 — neuroscience — Posted on 2024-01-13

2895 Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons

Prytkova, I. A.; Liu, Y.; Fernando, M. B.; Gameiro-Ros, I.; Popova, D.; Kamarajan, C.; Xuei, X.; Chorlian, D. B.; Edenberg, H. J.; Tischfield, J. A.; Porjesz, B.; Pang, Z. P.; Hart, R. P.; Goate, A. M.; Slesinger, P. A.

10.1101/2023.03.22.533236 — neuroscience — Posted on 2024-01-13

2896 BrainLM: A foundation model for brain activity recordings

Ortega Caro, J.; Oliveira Fonseca, A. H.; Averill, C.; Rizvi, S. A.; Rosati, M.; Cross, J. L.; Mittal, P.; Zappala, E.; Levine, D.; Dhodapkar, R. M.; Han, I.; Karbasi, A.; Abdallah, C. G.; van Dijk, D.

10.1101/2023.09.12.557460 — neuroscience — Posted on 2024-01-13

2897 Insights into Early Word Comprehension: Tracking the Neural Representations of Word Semantics in Infants.

Saha, R.; Campbell, J.; Werker, J. F.; Fyshe, A.

10.1101/2021.10.28.466334 — neuroscience — Posted on 2024-01-13

2898 Vestibular prepulse inhibition of the human blink reflex

Ciocca, M.; Hosli, S.; Hadi, Z.; Mahmud, M.; Tai, Y.; Seemungal, B. M.

10.1101/2024.01.09.574842 — neuroscience — Posted on 2024-01-13

2899 BBB recovery after stroke by self-replenishing E-pericytes transdifferentiated from local endothelial cells

Tingbo, L.; Zhu, Z.; Bingrui, Z.; Qingzhu, G.; Xuzhao, L.; Yuxiao, J.; Yiyi, Z.; Jiongfang, X.; Jiemin, J.; Jiaqi, T.; Peiran, Z.

10.1101/2023.12.07.570712 — neuroscience — Posted on 2024-01-13

2900 Sleep consolidation potentiates skill maintenance

Solano, A.; Lerner, G.; Griffa, G.; Deleglise, A.; Caffaro, P.; Riquelme, L.; Perez-Chada, D.; Della-Maggiore, V.

10.1101/2023.10.26.564031 — neuroscience — Posted on 2024-01-13

2901 A neural mechanism for learning from delayed postingestive feedback

Zimmerman, C. A.; Pan-Vazquez, A.; Wu, B.; Keppler, E. F.; Guthman, E. M.; Fetcho, R. N.; Bolkan, S. S.; McMannon, B.; Lee, J.; Hoag, A. T.; Lynch, L. A.; Janarthanan, S. R.; Lopez Luna, J. F.; Bondy, A. G.; Falkner, A. L.; Wang, S. S.-H.; Witten, I. B.

10.1101/2023.10.06.561214 — neuroscience — Posted on 2024-01-13

2902 How total mRNA influences cell growth

Calabrese, L.; Ciandrini, L.; Cosentino Lagomarsino, M.

10.1101/2023.03.17.533181 — systems biology — Posted on 2024-01-13

2903 On the dynamic contact angle of capillary-driven microflows in open channels

Tokihiro, J. C.; McManamen, A. M.; Phan, D. N.; Thongpang, S.; Blake, T. D.; Theberge, A. B.; Berthier, J.

10.1101/2023.04.24.537941 — bioengineering — Posted on 2024-01-13

2904 Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors

Nigam, A.; Hurley, M. F. D.; Li, F.; Konkolova, E.; Klima, M.; Trylcova, J.; Pollice, R.; Cınaroglu, S. S.; Levin-Konigsberg, R.; Handjaya, J.; Schapira, M.; Chau, I.; Perveen, S.; Ng, H.-L.; Kaniskan, H. U.; Han, Y.; Singh, S.; Gorgulla, C.; Kundaje, A.; Jin, J.; Voelz, V. A.; Weber, J.; Nencka, R.; Boura, E.; Vedadi, M.; Aspuru-Guzik, A.

10.1101/2023.10.03.560722 — biochemistry — Posted on 2024-01-13

2905 Structural analysis of the lncRNA SChLAP1 reveals protein binding interfaces and a conformationally heterogenous retroviral insertion

Falese, J. P.; McFadden, E. J.; D'Inzeo, C. A.; Hargrove, A. E.

10.1101/2021.10.21.465303 — biochemistry — Posted on 2024-01-13

2906 Evo-devo dynamics of hominin brain size

Gonzalez-Forero, M.

10.1101/2023.03.20.533421 — evolutionary biology — Posted on 2024-01-13

2907 Functional consequences of reductive protein evolution in a minimal eukaryotic genome

Jiang, J.; Qu, R.; Grigorescu, M.; Zhao, W.; Reinke, A. W.

10.1101/2023.12.31.573788 — evolutionary biology — Posted on 2024-01-13

2908 Maternal body condition affects the response of the gut microbiome to a widespread contaminant in larval spined toads

Tartu, S.; Pollet, N.; Clavereau, I.; Bouchard, G.; Brischoux, F.

10.1101/2023.12.18.572122 — ecology — Posted on 2024-01-13

2909 Exploring how the fast-slow pace of life continuum and reproductive strategies structure microorganism life history variation

Romeijn, J.; Smallegange, I. M.

10.1101/2022.11.28.517963 — ecology — Posted on 2024-01-13

2910 The human Dicer helicase domain mediates ATP hydrolysis and RNA rearrangement

Ciechanowska, K.; Szczepanska, A.; Szpotkowski, K.; Wojcik, K.; Urbanowicz, A.; Kurzynska-Kokorniak, A.

10.1101/2023.06.28.546842 — molecular biology — Posted on 2024-01-13

2911 Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region

Morales-Gregorio, A.; Kurth, A. C.; Ito, J.; Kleinjohann, A.; Barthelemy, F. V.; Brochier, T.; Grün, S.; van Albada, S. J.

10.1101/2023.06.14.544966 — neuroscience — Posted on 2024-01-13

2912 OpenSIM: open source microscope add-on for structured illumination microscopy

Hannebelle, M. T. M.; Raeth, E.; Leitao, S.; Lukes, T.; Pospisil, J.; Toniolo, C.; Venzin, O. F.; Chrisnandy, A.; Swain, P. P.; Ronceray, N.; Lutolf, M. P.; Oates, A. C.; Hagen, G. M.; Lasser, T.; Radenovic, A.; Mckinney, J. D.; Fantner, G. E.

10.1101/2023.06.16.545316 — bioengineering — Posted on 2024-01-13

2913 The disruption of CtBP regulates DUX-dependent and -independent genetic program for the 2-cell-like state in murine embryonic stem cells

Sugiyama, K.; Yoshioka, K.; Hayakawa, N.; Marutani, M.; Masuda, R.; Abadi, S. A.; Seki, Y.

10.1101/2024.01.12.575352 — cell biology — Posted on 2024-01-13

2914 Heritability estimation of subcortical volumes in a multi-ethnic multi-site cohort study

Coffman, C.; Feczko, E.; Larsen, B.; Tervo-Clemmens, B.; Conan, G.; Lundquist, J. T.; Houghton, A.; Moore, L. A.; Weldon, K. B.; McCollum, r.; Perrone, A. J.; Fayzullobekova, B.; Madison, T. J.; Earl, E.; Miranda-Dominguez, O.; Fair, D. A.; Basu, S.

10.1101/2024.01.11.575231 — genomics — Posted on 2024-01-12

2915 Notch Inhibition Enhances Morphological Reprogramming of microRNA-Induced Human Neurons

Burbach, K. F.; Yoo, A.

10.1101/2024.01.12.575384 — developmental biology — Posted on 2024-01-12

2916 C. elegans epicuticlins define specific compartments in the apical extracellular matrix and function in wound repair

Pooranachithra, M.; Jyo, E. M.; Ernst, A. M.; Chisholm, A. D.

10.1101/2024.01.12.575393 — developmental biology — Posted on 2024-01-13

2917 Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish

Peloggia, J.; Lush, M. E.; Tsai, Y.-Y.; Wood, C.; Piotrowski, T.

10.1101/2024.01.12.575421 — developmental biology — Posted on 2024-01-13

2918 D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability

Rona, G.; Miwatani-Minter, B.; Zhang, Q.; Goldberg, H. V.; Kerzhnerman, M. A.; Howard, J. B.; Simoneschi, D.; Lane, E.; Hobbs, J. W.; Sassani, E.; Wang, A. A.; Keegan, S.; Laverty, D. J.; Piett, C. G.; Pongor, L. S.; Xu, M. L.; Andrade, J.; Thomas, A.; Sicinski, P.; Askenazi, M.; Ueberheide, B.; Fenyo, D.; Nagel, Z. D.; Pagano, M.

10.1101/2024.01.12.575420 — cell biology — Posted on 2024-01-13

2919 Evidence of Histone H2A.Z Deacetylation and Cardiomyocyte Dedifferentiation in Infarcted/Tip60-depleted Hearts

Wang, X.; Kulik, K.; Wan, T. C.; Lough, J. W.; Auchampach, J. A.

10.1101/2024.01.11.575312 — cell biology — Posted on 2024-01-13

2920 Adenomatous polyposis coli (APC) regulates internalization and signaling of the chemorepellent receptor, Roundabout (ROBO) 1

Huang, Y.-W.; St-Germain, J.; Pang, B. W.; Collins, R. F.; Coyaud, E.; Li, W.; Mohamed, A.; Raught, B.; Grinstein, S.; Robinson, L. A.

10.1101/2024.01.12.574717 — cell biology — Posted on 2024-01-13

2921 FOXO-regulated Deaf1 controls muscle regeneration through autophagy

Goh, K. Y.; Lee, W. X.; Choy, S. M.; Krishnan Priyadarshini, G.; Chua, K.; Tan, Q. H.; Low, S. Y.; Chin, H. S.; Wong, C. S.; Huang, S.-Y.; Fu, N. Y.; Nishiyama, J.; Harmston, N.; Tang, H.-W.

10.1101/2024.01.12.575306 — cell biology — Posted on 2024-01-13

2922 Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development

Lagani, G. D.; Lin, W.; Natarajan, S.; Lampl, N.; Harper, E. R.; Emili, A.; Beffert, U.; Ho, A.

10.1101/2024.01.12.575269 — neuroscience — Posted on 2024-01-12

2923 The relationship between white matter architecture and language lateralisation in the healthy brain

Andrulyte, I.; de Bezenac, C.; Branzi, F.; Forkel, S. J.; Taylor, P. N.; Keller, S. S.

10.1101/2024.01.12.572159 — neuroscience — Posted on 2024-01-12

2924 Genopyc: a python library for investigating the genomic basis of complex diseases

Gualdi, F.; Oliva, B.; Pinero, J.

10.1101/2024.01.11.575316 — bioinformatics — Posted on 2024-01-12

2925 Comparative analysis of multiplexed in situ gene expression profiling technologies

Hartman, A.; Satija, R.

10.1101/2024.01.11.575135 — genomics — Posted on 2024-01-12

2926 Cell-type-specific origins of spinal rhythmicity at different locomotor speeds in larval zebrafish

Agha, M.; Kishore, S.; McLean, D. L.

10.1101/2024.01.11.575271 — neuroscience — Posted on 2024-01-12

2927 Urban greenspace aerobiomes are shaped by soil conditions and land cover type

Brame, J. E.; Liddicoat, C.; Abbott, C. A.; Cando-Dumancela, C.; Robinson, J. M.; Breed, M. F.

10.1101/2024.01.12.575340 — ecology — Posted on 2024-01-12

2928 Seasonal dynamics and drivers of microbial communities in a temperate dimictic lake: insights from metabarcoding and machine learning

Karlicki, M.; Bednarska, A.; Halakuc, P.; Maciszewski, K.; Karnkowska, A.

10.1101/2024.01.12.575328 — ecology — Posted on 2024-01-12

2929 Mapping planktonic communities: a network approach to assess the role of scale and centrality on their diversity and composition

Cunillera-Montcusi, D.; Bengtsson, M.; Matthews, B.; Preiler, C.; Horvath, Z.; Vad, C. F.; Ptacnik, R.

10.1101/2024.01.11.574175 — ecology — Posted on 2024-01-12

2930 Intense storms affect sinking particle fluxes after the North Atlantic diatom spring bloom

Romanelli, E.; Giering, S. L. C.; Estapa, M.; Siegel, D. A.; Passow, U.

10.1101/2024.01.11.575202 — biochemistry — Posted on 2024-01-12

2931 Wnt target gene Ascl4 is dispensable for skin appendage development

Papagno, V.; Sulic, A.-M.; Satta, J. P.; Kaffash Hoshiar, A.; Kumar, V.; Jernvall, J.; Mikkola, M. L.

10.1101/2024.01.12.575337 — developmental biology — Posted on 2024-01-12

2932 Interneuron-like features of microglia in the mouse outer retina

Toros, S.; Kane, T.; Hare, A.; Abbar, H.; Madoo, A.; De Rossi, G.; Powell, K.; Rizzi, M.

10.1101/2024.01.12.575392 — neuroscience — Posted on 2024-01-12

2933 Population Bursts in a Modular Neural Network as a Mechanism for Synchronized Activity in KNDy Neurons

Blanco, W.; Tabak, J.; Bertram, R.

10.1101/2024.01.12.575324 — neuroscience — Posted on 2024-01-12

2934 Deciphering the astrocytic contribution to learning and relearning

Squadrani, L.; Wert-Carvajal, C.; Mueller-Komorowska, D.; Bohmbach, K.; Henneberger, C.; Verzelli, P.; Tchumatchenko, T.

10.1101/2024.01.12.572819 — neuroscience — Posted on 2024-01-12

2935 Sexually dimorphic effects of Amylin 1 receptor activation in trigeminovascular neurons

Labastida-Ramirez, A.; Rubio-Beltran, E.; Holland, P. R.; Hoffmann, J.

10.1101/2024.01.12.575235 — neuroscience — Posted on 2024-01-12

2936 How smart was T. rex? Testing claims of exceptional cognition in dinosaurs and the application of neuron count estimates in palaeontological research

Caspar, K. R.; Gutierrez-Ibanez, C.; Bertrand, O. C.; Carr, T.; Colbourne, J.; Erb, A.; George, H.; Holtz, T. R.; Naish, D.; Wiley, D. R.; Hurlburt, G. R.

10.1101/2024.01.10.575006 — zoology — Posted on 2024-01-12

2937 Molecular signatures in rDNA internal transcribed spacers ITS1 and ITS2 for species characterization with novel primer sets

IMRAN, M.; NAFEES, S.

10.1101/2024.01.10.575031 — zoology — Posted on 2024-01-12

2938 A systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms

Crowl, S.; Coleman, M. B.; Chaphiv, A.; Naegle, K. M.

10.1101/2024.01.10.575062 — systems biology — Posted on 2024-01-12

2939 Atrial Proteomic Profiling Reveals a Switch Towards Profibrotic Gene Expression Program in CREM-IbΔC-X Mice with Persistent Atrial Fibrillation

Zhao, S.; Hulsurkar, M.; Lahiri, S.; Aguilar-Sanchez, Y.; Munivez, E.; Muller, F.-U.; Jain, A.; Malovannaya, A.; Yiu, C. H. K.; Reilly, S.; Wehrens, X.

10.1101/2024.01.10.575097 — systems biology — Posted on 2024-01-12

2940 The impact of kinship composition on social structure

Pereira, A. D. S.; Pavez-Fox, M. A.; Hart, J. D. A.; Negron-Del Valle, J. E.; Phillips, D.; Casanova, C.; De Moor, D.; Brent, L. J. N.

10.1101/2024.01.11.575037 — animal behavior and cognition — Posted on 2024-01-12

2941 Automated behavioral analysis reveals that mice employ a bait-and-switch escape mechanism to de-escalate social conflict.

Clein, R.; Warren, M.; Neunuebel, J. P.

10.1101/2024.01.12.575321 — animal behavior and cognition — Posted on 2024-01-12

2942 Neural variability compresses with increasing belief precision during Bayesian inference

Skowron, A.; Kosciessa, J. Q.; Lorenz, R.; Hertwig, R.; van den Bos, W.; Garrett, D. D.

10.1101/2024.01.11.575180 — neuroscience — Posted on 2024-01-12

2943 Neuronal subtypes and connectivity of the adult mouse paralaminar amygdala

Saxon, D.; Alderman, P. J.; Sorrells, S. F.; Vicini, S.; Corbin, J. G.

10.1101/2024.01.11.575250 — neuroscience — Posted on 2024-01-12

2944 Training interoceptive awareness with real-time haptic vs. visual heartbeat feedback

Dobrushina, O. R.; Tamim, Y.; Wald, I. Y.; Maimon, A.; Amedi, A.

10.1101/2024.01.12.575196 — neuroscience — Posted on 2024-01-12

2945 Neuropeptidergic regulation of neuromuscular signaling in larval zebrafish alters swimming behavior and synaptic transmission

Dill, H.; Liewald, J. F.; Becker, M.; Seidenthal, M.; Gottschalk, A.

10.1101/2024.01.12.575339 — neuroscience — Posted on 2024-01-12

2946 Do microsaccades vary with discriminability around the visual field?

Purokayastha, S.; Roberts, M.; Carrasco, M.

10.1101/2024.01.11.575288 — neuroscience — Posted on 2024-01-12

2947 Secreted Particle Information Transfer (SPIT) - A Cellular Platform For In Vivo Genetic Engineering

Charlesworth, C. T.; Homma, S.; Suchy, F.; Wang, S.; Bhadhury, J.; Amaya, A. K.; Camarena, J.; Zhang, J.; Tan, T. K.; Igarishi, K. J.; Nakauchi, H.

10.1101/2024.01.11.575257 — synthetic biology — Posted on 2024-01-12

2948 Subtle, but perceptible, sexual dichromatism and disassortative mating based on plumage reflectance in Black Terns (Chlidonias niger)

Baldassarre, D. T.; Davis, K. M.; Shealer, D. A.

10.1101/2024.01.11.575209 — animal behavior and cognition — Posted on 2024-01-12

2949 The novel linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse embryonic development.

Kim, S. E.; Kim, H. Y.; Wlodarczyk, B. J.; Finnell, R. H.

10.1101/2024.01.11.575263 — genetics — Posted on 2024-01-12

2950 Spring temperature and land use change are associated with Rana temporaria reproductive success and phenology

Oliver, K. E.; Harrison, X. A.

10.1101/2024.01.12.575320 — ecology — Posted on 2024-01-12

2951 Differential tissue deformability underlies shape divergence of the embryonic brain and spinal cord under fluid pressure

McLaren, S. B. P.; Xue, S.-L.; Ding, S.; Winkel, A.; Baldwin, O.; Dwarakacherla, S.; Franze, K.; Hannezo, E.; Xiong, F.

10.1101/2024.01.12.575349 — developmental biology — Posted on 2024-01-12

2952 Morphologically defined substages of tail tip morphogenesis in C. elegans males

Kiontke, K. C.; Woronik, A.; Fitch, D. H. A.

10.1101/2024.01.11.575265 — developmental biology — Posted on 2024-01-12

2953 Optimization of Anticodon Edited Transfer RNAs (ACE-tRNAs) Function in Translation for Suppression of Nonsense Mutations

Porter, J. J.; Ko, W.; Sorensen, E. G.; Lueck, J. D.

10.1101/2024.01.11.575297 — molecular biology — Posted on 2024-01-12

2954 Integrative analysis in head and neck cancer reveals distinct role of miRNome and methylome as tumour epigenetic drivers

Mandic, K.; Milutin Gasperov, N.; Bozinovic, K.; Dediol, E.; Sincic, N.; Grce, M.; Baresic, A.; Sabol, I.

10.1101/2024.01.11.575141 — molecular biology — Posted on 2024-01-12

2955 Integrity assay for messenger RNA in mouse and human brain samples and synaptosomal preparations

Bujanauskiene, D.; Merkevicius, K.; Kuliesiute, U.; Denkovskij, J.; Kutanovas, S.; Luksys, G.; Rocka, S.; Bernotiene, E.; Neniskyte, U.

10.1101/2024.01.12.575353 — molecular biology — Posted on 2024-01-12

2956 Molecular biological methods to assess different Botrytis cinerea strains on grapes

Backmann, L.; Schmidtmann, K.; Wegmann-Herr, P.; Juergens, A.; Scharfenberger-Schmeer, M.

10.1101/2024.01.12.575343 — molecular biology — Posted on 2024-01-12

2957 Discovery and characterisation of new phage targeting uropathogenic Escherichia coli

Kangachar, S. A.; Logel, D. Y.; Trofimova, E.; Zhu, H. X.; Zaugg, J.; Schembri, M. A.; Weynberg, K. D.; Jaschke, P. R.

10.1101/2024.01.12.575291 — microbiology — Posted on 2024-01-12

2958 Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes

Bangash, A.; Cubuk, C.; Iseppon, F.; Haroun, R.; Luiz, A. P.; Arcangeletti, M.; Gossage, S. J.; Santana-Varela, S.; Cox, J. J.; Lewis, M. J.; Wood, J. N.; Zhao, J.

10.1101/2024.01.11.575033 — neuroscience — Posted on 2024-01-12

2959 Through the lens of causal inference: Decisions and pitfalls of covariate selection

Chen, G.; Cai, Z.; Taylor, P. A.

10.1101/2024.01.11.575211 — neuroscience — Posted on 2024-01-12

2960 Phase Resetting Curves Determine Stability of Synchrony in One and Two Clusters of Pulse Coupled Oscillators with Delays

Vedururu Srinivas, A.; Canavier, C. C.

10.1101/2024.01.11.575222 — neuroscience — Posted on 2024-01-12

2961 Erroneous compensation for long-latency feedback delays as origin of Essential Tremor

Blondiaux, F.; Colmant, L.; Lebrun, L.; Hanseeuw, B.; Crevecoeur, F.

10.1101/2024.01.11.575204 — neuroscience — Posted on 2024-01-12

2962 Neuronal microstructural changes in the human brain are associated with neurocognitive aging

Singh, K.; Barsoum, S.; Schilling, K. G.; An, Y.; Ferrucci, L.; Benjamini, D.

10.1101/2024.01.11.575206 — neuroscience — Posted on 2024-01-12

2963 Connectomic and behavioral alterations in creatine transporter deficiency are partially normalized by gene therapy

Montani, C.; Galbusera, A.; D'Epifanio, B.; Ghirardini, E.; Cornuti, S.; Pasquin Mariani, J.-C. R.; de Guzman, A. E.; Mandrup Bertozzi, S.; Armirotti, A.; Baroncelli, L.; Gozzi, A.

10.1101/2024.01.12.575377 — neuroscience — Posted on 2024-01-12

2964 PyLossless: A non-destructive EEG processing pipeline

Huberty, S.; Desjardins, J.; Collins, T.; Elsabbagh, M.; O'Reilly, C.

10.1101/2024.01.12.575323 — neuroscience — Posted on 2024-01-12

2965 Obesity Facilitates Sex-Specific Improvement In Cognition And Neuronal Function In A Rat Model Of Alzheimer's Disease

Lai, A. Y.; Almanza, D. L. V.; Ribeiro, J. A.; Hill, M. E.; Mendrozos, M.; Koletar, M. M.; Stefanovic, B.; McLaurin, J.

10.1101/2024.01.11.575200 — neuroscience — Posted on 2024-01-12

2966 Simulated brain networks reflecting progression of Parkinson's disease

Jung, K.; Eickhoff, S. B.; Caspers, J.; UKD-PD team, ; Popovych, O. V.

10.1101/2024.01.12.574450 — neuroscience — Posted on 2024-01-12

2967 Timing and Amplitude of Catch-up Saccades to Accelerating Targets

Dore, S.; Coutinho, J. D.; Brooks, E.; Khan, A. Z.; Lefevre, P.; Blohm, G.

10.1101/2024.01.11.575233 — neuroscience — Posted on 2024-01-12

2968 EMG-to-torque models for exoskeleton assistance: a framework for the evaluation of in situ calibration

Quesada, L.; Verdel, D.; Bruneau, O.; Berret, B.; Amorim, M.-A.; Vignais, N.

10.1101/2024.01.11.575155 — neuroscience — Posted on 2024-01-12

2969 Distinct alterations in white matter properties and organization related to maternal treatment initiation in neonates exposed to HIV but uninfected

Magondo, N.; Meintjes, E. M.; Warton, F. L.; Little, F.; van der Kouwe, A.; Laughton, B.; Jankiewicz, M.; Holmes, M.

10.1101/2024.01.11.575169 — neuroscience — Posted on 2024-01-12

2970 Human spinal interneurons repair the injured spinal cord through synaptic integration

Zholudeva, L.; Fortino, T.; Agrawal, A.; Vila, O. F.; Williams, M.; McDevitt, T.; Lane, M. A.; Srivastava, D.

10.1101/2024.01.11.575264 — neuroscience — Posted on 2024-01-12

2971 Dynamic Network Analysis of Electrophysiological Task Data

Gohil, C.; Kohl, O.; Huang, R.; van Es, M. W. J.; Parker Jones, O.; Hunt, L. T.; Quinn, A. J.; Woolrich, M. W.

10.1101/2024.01.12.567026 — neuroscience — Posted on 2024-01-12

2972 Transcriptome Dynamics in Mouse Amygdala under Acute and Chronic Stress Revealed by Thio-labeled RNA Sequencing

Zhao, D.; Zhang, L.; Yang, Y.

10.1101/2024.01.12.573386 — neuroscience — Posted on 2024-01-12

2973 Mechanisms and implications of high depolarization baseline offsets in conductance-based neuronal models

Kumar, A.; Shahul, A. K.; Bhalla, U. S.

10.1101/2024.01.11.575308 — neuroscience — Posted on 2024-01-12

2974 Node centrality in MEG resting-state networks covaries with neurotransmitter receptor and transporter density

Siebenhuehner, F.; Palva, M.; Palva, S.

10.1101/2024.01.11.575176 — neuroscience — Posted on 2024-01-12

2975 Response-locked theta dissociations reveal potential feedback signal following successful retrieval

Smith, D. E.; Wheelock, J. R.; Long, N. M.

10.1101/2024.01.11.575166 — neuroscience — Posted on 2024-01-12

2976 Synaptic Theory of Working Memory for Serial Order

Mongillo, G.; Tsodyks, M.

10.1101/2024.01.11.575157 — neuroscience — Posted on 2024-01-12

2977 Gray Matters: An Efficient Vision Transformer GAN Framework for Predicting Functional Network Connectivity Biomarkers from Brain Structure

Bi, Y.; Abrol, A.; Jia, S.; Sui, J.; Calhoun, V.

10.1101/2024.01.11.575307 — neuroscience — Posted on 2024-01-12

2978 Incorporating temporal information during featureengineering bolsters emulation of spatio-temporalemergence

Cain, J. Y.; Evarts, J. I.; Yu, J. S.; Bagheri, N.

10.1101/2024.01.11.575245 — systems biology — Posted on 2024-01-12

2979 Targeted LNPs deliver mRNA encoding IL-15 superagonists to balance efficacy and toxicity in cancer therapy

Yu, J.; Li, Q.; Luo, S.; Wang, X.; Cheng, Q.; Hu, R.

10.1101/2024.01.11.575299 — bioengineering — Posted on 2024-01-12

2980 Late-life dietary folate restriction reduces biosynthetic processes without compromising healthspan in mice

Blank, H. M.; Hammer, S. E.; Boatright, L.; Roberts, C.; Heyden, K. E.; Nagarajan, A.; Tsuchiya, M.; Brun, M.; Johnson, C. D.; Stover, P. J.; Sitcheran, R.; Kennedy, B. K.; Adams, L. G.; Kaeberlein, M.; Field, M. S.; Threadgill, D. W.; Andrews-Polymenis, H. L.; Polymenis, M.

10.1101/2024.01.12.575290 — molecular biology — Posted on 2024-01-12

2981 NSE5 subunit interacts with distant regions of the SMC arms in the Physcomitrium patens SMC5/6 complex

Vaculikova, J.; Hola, M.; Kralova, B.; Lelkes, E.; Stefanovie, B.; Vagnerova, R.; Angelis, K. J.; Palecek, J. J.

10.1101/2024.01.12.574989 — molecular biology — Posted on 2024-01-12

2982 Identification, structure and function of the methyltransferase involved in the biosynthesis of the dithiolopyrrolone antibiotic xenorhabdin

Su, L.; Westphalen, M.; Gellner, J.; Bode, E.; Koebel, T.; Gruen, P.; Alanjary, M.; Glatter, T.; Schindler, D.; Groll, M.; Bode, H. B.

10.1101/2024.01.12.575338 — microbiology — Posted on 2024-01-12

2983 Evaluation of the accuracy of bacterial genome reconstruction with Oxford Nanopore R10.4.1 long-read-only sequencing

Sanderson, N. D.; Hopkins, K.; Colpus, M.; Parker, M.; Lipworth, S.; Crook, D.; Stoesser, N.

10.1101/2024.01.12.575342 — microbiology — Posted on 2024-01-12

2984 Neural Network-Assisted Humanization of COVID-19 Hamster scRNAseq Data Reveals Matching Severity States in Human Disease

Friedrich, V. D.; Pennitz, P.; Wyler, E.; Adler, J. M.; Postmus, D.; Alves, L. G. T.; Prigann, J.; Pott, F.; Vladimirova, D.; Hoefler, T.; Goekeri, C.; Landthaler, M.; Goffinet, C.; Saliba, A.-E.; Scholz, M.; Witzenrath, M.; Trimpert, J.; Kirsten, H.; Nouailles, G.

10.1101/2024.01.11.574849 — immunology — Posted on 2024-01-12

2985 Tar Spot Disease Severity Influences Phyllosphere-Associated Bacterial and Fungal Microbiomes

Singh, R.; Shim, S.; Telenko, D. E. P.; Goodwin, S. B.

10.1101/2024.01.12.565617 — plant biology — Posted on 2024-01-12

2986 Spatial interactions modulate tumor growth and immune infiltration

Marzban, S.; Srivastava, S.; Kartika, S.; Bravo, R.; Safriel, R.; Zarski, A.; Anderson, A. R. A.; Chung, C. H.; Amelio, A. L.; West, J.

10.1101/2024.01.10.575036 — cancer biology — Posted on 2024-01-12

2987 Assessment of Gene Set Enrichment Analysis using curated RNA-seq-based benchmarks

Candia, J.; Ferrucci, L.

10.1101/2024.01.10.575094 — bioinformatics — Posted on 2024-01-12

2988 A Novel Imaging Mass Spectrometry Computational Tool for Biomedical Discovery: Untargeted pixel-by-pixel imaging of Metabolite Ratio Pairs

Cheng, H.; Miller, D.; Southwell, N.; Fischer, J.; Salbaum, M.; Kappen, C.; Hu, F.; Yang, C.; Gross, S.; D'Aurelio, M.; Chen, Q.

10.1101/2024.01.10.575105 — bioinformatics — Posted on 2024-01-12

2989 Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis

Pekayvaz, K.; Joppich, M.; Brambs, S.; Knottenberg, V.; Eivers, L.; Martinez-Navarro, A.; Kaiser, R.; Meissner, N.; Kilani, B.; Stockhausen, S.; Janjic, A. J.; Polewka, V.; Wendler, F. W.; zu Senden, A. D.; Leunig, A.; Voelkl, M.; Engelmann, B.; Hernandez Petzsche, M. R.; Boeckh-Behrens, T.; Liebig, T.; Dichgans, M.; Enard, W.; Zimmer, R.; Tiedt, S.; Massberg, S.; Nicolai, L.; Stark, K.

10.1101/2024.01.10.574518 — immunology — Posted on 2024-01-12

2990 A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis

Castillo, J. G.; DeBarge, R.; Mende, A.; Tenvooren, I.; Marquez, D. M.; Straub, A.; Busch, D. H.; Spitzer, M. H.; DuPage, M.

10.1101/2024.01.11.575237 — immunology — Posted on 2024-01-12

2991 Influence of social and semantic contexts in processing speech in noise

Abassi, E.; Zatorre, R.

10.1101/2024.01.10.575068 — neuroscience — Posted on 2024-01-12

2992 Idiosyncratic pupil regulation in autistic children

Bleimeister, I. H.; Avni, I.; Granovetter, M. C.; Meiri, G.; Ilan, M.; Michaelovski, A.; Menashe, I.; Behrmann, M.; Dinstein, I.

10.1101/2024.01.10.575072 — neuroscience — Posted on 2024-01-12

2993 Shear stress-induced restoration of pulmonary endothelial barrier function following ischaemia reperfusion injury requires VEGFR2 signalling

Walsh, D.; Kostyunina, D. S.; Boylan, J. F.; McLoughlin, P.

10.1101/2024.01.10.575020 — physiology — Posted on 2024-01-12

2994 Benchmarking computational tools for de novo motif discovery

Simonetti, L.; Ivarsson, Y.; Davey, N. E.

10.1101/2024.01.12.574168 — bioinformatics — Posted on 2024-01-12

2995 LoopSage: An Energy-Based Monte Carlo approach for the Loop Extrusion Modelling of Chromatin

Korsak, S.; Plewczynski, D.

10.1101/2024.01.10.574968 — genomics — Posted on 2024-01-12

2996 How many specimens make a sufficient training set for automated 3D feature extraction?

Mulqueeney, J. M.; Searle-Barnes, A.; Brombacher, A.; Sweeney, M.; Goswami, A.; Ezard, T.

10.1101/2024.01.10.575054 — evolutionary biology — Posted on 2024-01-12

2997 Measuring the Stoichiometry of Microbial Parasite Infrapopulations One Cell at a Time using Energy Dispersive Spectroscopy

Narr, C. F.; Binger, S.; Sedlacek, E.; Anderson, B.; Shoemaker, G.; Stanley, A.; Stokoski, M.; Hall, E.

10.1101/2024.01.11.575226 — ecology — Posted on 2024-01-12

2998 Tissue-specific RNA-seq defines genes governing male tail tip morphogenesis in C. elegans

Kiontke, K. C.; Herrera, R. A.; Mason, D. A.; Patel, Y.; Vernooy, S.; Woronik, A.; Fitch, D. H. A.

10.1101/2024.01.12.575210 — developmental biology — Posted on 2024-01-12

2999 A removable and cosmopolitan dsRNA Toti-like virus causes latent infection in a model diatom strain

Zhang, J.; Li, C.; Xiong, X.; Guo, K.; Feng, Y.; Zhang, H.; Hu, H.; Li, X.

10.1101/2024.01.12.575345 — microbiology — Posted on 2024-01-12

3000 Seed coating with phages for sustainable plant biocontrol of plant pathogens and influence of the seed coat mucilage

Erdrich, S.; Schurr, U.; Frunzke, J.; Arsova, B.

10.1101/2024.01.12.575253 — microbiology — Posted on 2024-01-12

3001 Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

Chen, D.; Philippidou, P.; Brenha, B. d. F.; Schaffer, A. E.; Miranda, H. C.

10.1101/2024.01.11.575304 — neuroscience — Posted on 2024-01-12

3002 Loss of postsynaptic NMDARs drives nanoscale reorganization of Munc13-1 and PSD-95

Dharmasri, P. A.; DeMarco, E. M.; Anderson, M. C.; Levy, A. D.; Blanpied, T. A.

10.1101/2024.01.12.574705 — neuroscience — Posted on 2024-01-12

3003 Single residues in the complexin N-terminus exhibit distinct phenotypes in synaptic vesicle fusion

Toulme, E.; Murach, J.; Baerfuss, S.; Kroll, J.; Malsam, J.; Trimbuch, T.; Herman, M. A.; Soellner, T. H.; Rosenmund, C.

10.1101/2024.01.12.575336 — neuroscience — Posted on 2024-01-12

3004 Time dependent changes in feeding behavior and energy balance associated with weight gain in mice fed obesogenic diets

Fathi, P. A.; Bales, M. B.; Ayala, J. E.

10.1101/2024.01.10.575043 — physiology — Posted on 2024-01-12

3005 PCTA, A PAN-CANCER CELL LINE TRANSCRIPTOME ATLAS

Cheng, S.; Li, L.; Yu, X.

10.1101/2024.01.10.575087 — cancer biology — Posted on 2024-01-12

3006 A Surgical Technique for Individual Control of the Muscles of the Rabbit Lower Hind-limb.

Baggaley, M.; Sawatsky, A.; Ross, S. A.; Herzog, W.

10.1101/2024.01.10.575091 — biophysics — Posted on 2024-01-12

3007 Synaptotagmin 7 C2 domains induce membrane curvature stress via electrostatic interactions and the wedge mechanism

Beaven, A. H.; Bikkumalla, V.; Chon, N. L.; Matthews, A. E.; Lin, H.; Knight, J. D.; Sodt, A. J.

10.1101/2024.01.10.575084 — biophysics — Posted on 2024-01-12

3008 Improved Early Detection of Drug-Induced Liver Injury by Integrating Predicted in vivo and in vitro Data

Seal, S.; Williams, D. P.; Hosseini-Gerami, L.; Spjuth, O.; Bender, A.

10.1101/2024.01.10.575128 — bioinformatics — Posted on 2024-01-12

3009 RiboGraph: An interactive visualization system for ribosome profiling data at read length resolution

Chacko, J.; Ozadam, H.; Cenik, C.

10.1101/2024.01.11.575228 — bioinformatics — Posted on 2024-01-12

3010 Dynamic coexistence driven by physiological transitions in microbial communities

Narla, A.; Hwa, T.; Murugan, A.

10.1101/2024.01.10.575059 — ecology — Posted on 2024-01-12

3011 Developmental toxicity of pre-production plastic pellets affects a large swathe of invertebrate taxa

Jimenez Guri, E.; Paganos, P.; La Vecchia, C.; Annona, G.; Caccavale, F.; Molina, M. D.; Ferrandez-Roldan, A.; Donnellan, R. D.; Salatiello, F.; Johnstone, A. N.; Eliso, M. C.; Spagnuolo, A.; Canestro, C.; Albalat, R.; Martin-Duran, J. M.; Williams, E. A.; D'Aniello, E.; Arnone, M. I.

10.1101/2024.01.10.574808 — developmental biology — Posted on 2024-01-12

3012 Mapping the developmental trajectories of SAP-dependent innate-like gamma delta (γδ) T cells

Mistri, S. K.; Hilton, B. M.; Horrigan, K. J.; Andretta, E. S.; Savard, R.; Dienz, O.; Hampel, K. J.; Gerrard, D. L.; Rose, J. T.; Sidiropoulos, N.; Majumdar, D.; Boyson, J. E.

10.1101/2024.01.10.575073 — immunology — Posted on 2024-01-12

3013 Criticality and universality in neuronal cultures during 'up' and 'down' states

Yaghoubi, M.; Orlandi, J. G.; Colicos, M. A.; Davidsen, J.

10.1101/2024.01.10.575061 — neuroscience — Posted on 2024-01-12

3014 Global Huntingtin Knockout in Adult Mice Leads to Fatal Neurodegeneration that Spares the Pancreas

Bragg, R. M.; Mathews, E. W.; Grindeland, A.; Cantle, J. P.; Howland, D.; Vogt, T. F.; Carroll, J. B.

10.1101/2024.01.11.575238 — neuroscience — Posted on 2024-01-12

3015 Devaluing memories of reward: A case for dopamine

Fry, B.; Russell, N.; Fex, V.; Mo, B.; Pence, N.; Beatty, J.; Manfredsson, F.; Toth, B.; Burgess, C.; Gershman, S. J.; Johnson, A.

10.1101/2024.01.10.575106 — neuroscience — Posted on 2024-01-12

3016 Spiking Neuron-Astrocyte Networks for Image Recognition

Lorenzo, J.; Binczak, S.; Rico-Gallego, J.-A.; Jacquir, S.

10.1101/2024.01.10.574963 — neuroscience — Posted on 2024-01-12

3017 Activity-dependent expression of Fezf2 regulates inhibitory synapse formation in pyramidal cells

Kroon, T.; Sanalidou, S.; Maeso, P.; Garces, T.; Yang, H.; Rico, B.

10.1101/2024.01.11.575171 — neuroscience — Posted on 2024-01-12

3018 Elucidating an implicit-statistical learning brain network: Coordinate-based meta-analyses and functional connectivity profiles of artificial grammar learning in healthy adults

Ramage, A. E.; Cote, K.; Thorson, J. C.; Lerner, K.; Riedel, M. C.; Laird, A. R.

10.1101/2024.01.10.575023 — neuroscience — Posted on 2024-01-12

3019 The shared genetic basis of leaf morphology and tensile resistance underlies the effect of growing season length in a widespread perennial grass

Durant, P. C.; Bhasin, A.; Juenger, T. E.; Heckman, R. W.

10.1101/2024.01.10.575100 — plant biology — Posted on 2024-01-12

3020 The decision of male medaka to mate or fight depends on two complementary androgen signaling pathways

Nishiike, Y.; Okubo, K.

10.1101/2024.01.10.574747 — physiology — Posted on 2024-01-12

3021 CD14 Blockade Does Not Improve Outcomes of Deep Vein Thrombosis Following Inferior Vena Cava Stenosis in Mice

Pandey, N.; Kaur, H.; Chandaluri, L.; Anand, S. K.; Chokhawala, H.; Magdy, T.; Stokes, K.; Orr, A. W.; Rom, O.; Dhanesha, N.

10.1101/2024.01.10.575099 — pathology — Posted on 2024-01-12

3022 DNA microbeads for spatio-temporally controlled morphogen release within organoids

Afting, C.; Walther, T.; Wittbrodt, J.; Göpfrich, K.

10.1101/2024.01.10.575045 — bioengineering — Posted on 2024-01-12

3023 Acanthella acuta Mitochondrial DNA: Linear Architecture and Other Unique Features

Ahmed, M.; Kayal, E.; Lavrov, D. V.

10.1101/2024.01.10.575101 — evolutionary biology — Posted on 2024-01-12

3024 Seasonal behavioral patterns of the Caqueta titi monkey (Plecturocebus caquetensis)

Acero-Murcia, A. C.; Almario-Vaquiro, L.; Ortega, Z.; Garcia, J.; Camacho, R. L.; Defler, T.

10.1101/2024.01.10.573946 — ecology — Posted on 2024-01-12

3025 The Porcine Skin Microbiome Exhibits Broad Fungal Antagonism

De La Cruz, K. F.; Townsend, E. C.; Cheong, J. A.; Salamzade, R.; Liu, A.; Sandstrom, S.; Davila, E.; Huang, L.; Xu, K. H.; Wu, S. Y.; Meudt, J. J.; Shanmuganayagam, D.; Gibson, A. L.; Kalan, L. R.

10.1101/2024.01.12.574414 — microbiology — Posted on 2024-01-12

3026 A Germinal Center Checkpoint of AIRE in B Cells LimitsAntibody Diversification

Zhou, J. Z.; Huang, B.; Pei, B.; Sun, G.; Pawlitz, M.; ZHANG, W.; Li, x.; Hokynar, K. C.; Yao, F.; Perera, M. L.; Wei, S.; Zheng, S.; Polin, L. A.; Poulik, J. M.; Ranki, A.; Krohn, K.; Cunningham-Rundles, C.; Yang, N.; Bhagwat, A.; Yu, K.; Peterson, P.; Kisand, K.; Vuong, B. Q.; Cerutti, A.; Chen, K.

10.1101/2024.01.10.574926 — immunology — Posted on 2024-01-12

3027 Internal regulation between constitutively expressed T cell coinhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants

Adegoke, A. O.; Thangavelu, G.; Chou, T.-F.; Petersen, M.; Kakugawa, K.; May, J.; Ellestad, K. K.; Boon, L.; Bretscher, P. A.; Cheroutre, H.; Kronenberg, M.; Baldwin, T. A.; Anderson, C. C.

10.1101/2024.01.10.574913 — immunology — Posted on 2024-01-12

3028 Extracting interpretable signatures of whole-brain dynamics through systematic comparison

Bryant, A. G.; Aquino, K.; Parkes, L.; Fornito, A.; Fulcher, B. D.

10.1101/2024.01.10.573372 — neuroscience — Posted on 2024-01-12

3029 Stopping Speed to Auditory and Visual Stop Signals Depends on Go Signal Modality

Weber, S.; Salomoni, S. E.; St George, R. J.; Hinder, M. R.

10.1101/2024.01.10.575126 — neuroscience — Posted on 2024-01-12

3030 Low-intensity focused ultrasound to the insula and dorsal anterior cingulate has site-specific and pressure dependent effects on pain during measures of central sensitization

In, A.; Strohman, A.; Payne, B.; Legon, W.

10.1101/2024.01.10.575098 — neuroscience — Posted on 2024-01-12

3031 Regional Microglial Response in Enthorino-hippocampal Slice Cultures to Schaffer Collateral Lesion and Metalloproteinases Modulation.

Virtuoso, A.; Galanis, C.; Lenz, M.; Papa, M.; Vlachos, A.

10.1101/2024.01.10.575060 — neuroscience — Posted on 2024-01-12

3032 Neuromark PET: A multivariate method for Estimating and comparing whole brain functional networks and connectomes from fMRI and PET data

Saha, D. K.; bohsali, A.; Saha, R.; Hajjar, I.; Calhoun, V.

10.1101/2024.01.10.575131 — neuroscience — Posted on 2024-01-12

3033 Sleep selectively and durably enhances real-world sequence memory

Diamond, N. B.; Simpson, S.; Baena Perez, D.; Murray, B.; Fogel, S.; Levine, B.

10.1101/2024.01.10.575038 — neuroscience — Posted on 2024-01-12

3034 Dysregulated synaptic gene expression in oligodendrocytes of spinal and bulbar muscular atrophy

Iida, M.; Sahashi, K.; Hirunagi, T.; Sakakibara, K.; Maeda, K.; Ogura, Y.; Iizuka, M.; Akashi, T.; Hinohara, K.; Katsuno, M.

10.1101/2024.01.11.575248 — neuroscience — Posted on 2024-01-12

3035 Neural Ensembles in the Lateral Prefrontal Cortex Temporally Multiplex Task Features During Virtual Navigation

Abbass, M.; Corrigan, B. W.; Johnston, R.; Gulli, R. A.; Sachs, A.; Lau, J. C.; Martinez-Trujillo, J. C.

10.1101/2024.01.10.574378 — neuroscience — Posted on 2024-01-12

3036 Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)

Joseph, T. T.; Bu, W.; Haji-Ghassemi, O.; Chen, Y. S.; Woll, K.; Allen, P. D.; Brannigan, G.; van Petegem, F.; Eckenhoff, R. G.

10.1101/2024.01.10.575040 — pharmacology and toxicology — Posted on 2024-01-12

3037 High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myelogenous leukemia

Rudzinska-Radecka, M.; Turos-Korgul, L.; Mukherjee, D.; Podszywalow-Bartnicka, P.; Piwocka, K.; Guzowski, J.

10.1101/2024.01.10.575000 — cancer biology — Posted on 2024-01-12

3038 Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

Poluben, L.; Nouri, M.; Liang, J.; Varkaris, A.; Ersoy-Fazlioglu, B.; Voznesensky, O.; Lee, I.; Qiu, X.; Cato, L.; Seo, J.-H.; Freedman, M.; Sowalsky, A.; Lack, N.; Corey, E.; Nelson, P.; Brown, M.; Long, H.; Balk, S.; Russo, J.

10.1101/2024.01.10.575110 — cancer biology — Posted on 2024-01-12

3039 Binding of PUFA stabilizes a conductive state of the selectivity filter in IKs channels

Golluscio, A.; Eldstrom, J.; Jowais, J. J.; Perez, M. E.; Cunningham, K. P.; De La Cruz, A.; Wu, X.; Fedida, D.; Larsson, P.

10.1101/2024.01.11.575247 — biophysics — Posted on 2024-01-12

3040 On-chip large-scale-integration and 2D collective modes of genetically programmed artificial cells

Ricouvier, J.; Mostov, P.; Shabtai, O.; Tayar, A.; Karzbrun, E.; Khakimzhan, A.; Noireaux, V.; Shulman Daube, S.; Bar-Ziv, R.

10.1101/2024.01.10.575012 — biophysics — Posted on 2024-01-12

3041 Sequence-Dependent Conformational Transitions of Disordered Proteins During Condensation

Wang, J.; Sundaravadivelu Devarajan, D.; Kim, Y. C.; Nikoubashman, A.; Mittal, J.

10.1101/2024.01.11.575294 — biophysics — Posted on 2024-01-12

3042 Generative artificial intelligence performs rudimentary structural biology modelling

Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.

10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-01-12

3043 Cross-Domain Text Mining of Pathophysiological Processes Associated with Diabetic Kidney Disease

Patidar, K.; Deng, J. H.; Mitchell, C. S.; Ford Versypt, A. N.

10.1101/2024.01.10.575096 — bioinformatics — Posted on 2024-01-12

3044 Defining a small-molecule stimulator of the human Hsp70-disaggregase system with selectivity for DnaJB proteins

Chuang, E.; Cupo, R. R.; Bevan, J. R.; Rice, M. L.; Mao, S.; Gorenberg, E. L.; Mack, K. L.; Huryn, D. M.; Wipf, P.; Brodsky, J. L.; Shorter, J.

10.1101/2024.01.11.575109 — biochemistry — Posted on 2024-01-12

3045 Widespread 3' UTR splicing regulates expression of oncogene transcripts in sequence-dependent and independent manners

Riley, J. J.; Alexandru-Crivac, C. N.; Bryce-Smith, S.; Wilson, S. A.; Sudbery, I. M.

10.1101/2024.01.10.575007 — genomics — Posted on 2024-01-12

3046 Iron deficiency in people with obesity drives defective natural killer cell mitochondrial fitness and function

DeBarra, C.; Ryan, E.; Sugrue, M.; Ryan, O.; Lynn, E.; Heneghan, H. M.; McCarthy, C.; Moynagh, P. N.; Sinclair, L. V.; Jones, N.; Hogan, A.; O Shea, D.

10.1101/2024.01.10.575005 — immunology — Posted on 2024-01-12

3047 The inevitability and superfluousness of cell types in spatial cognition

Luo, X.; Mok, R. M.; Love, B. C.

10.1101/2024.01.10.575026 — neuroscience — Posted on 2024-01-12

3048 Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

Goldberg, A. R.; Dovas, A.; Torres, D.; Das Sharma, S.; Mela, A.; Merricks, E. M.; Olabarria, M.; Shokoohm, L. A.; Zhao, H. T.; Kotidis, C.; Calvaresi, P.; Viswanathan, A.; Banu, M. A.; Razavilar, A.; Sudhakar, T. D.; Saxena, A.; Chokran, C.; Humala, N.; Mahajan, A.; Xu, W.; Metz, J. B.; Chen, C.; Bushong, E. A.; Boassa, D.; Ellisman, M. H.; Hillman, E. M. C.; McKhann, G. M.; Gill, B. J. A.; Rosenfeld, S. S.; Schevon, C. A.; Bruce, J. N.; Sims, P. A.; Peterka, D. S.; Canoll, P.

10.1101/2024.01.10.575092 — neuroscience — Posted on 2024-01-12

3049 Efficient analysis of toxicity and mechanism of food contaminants using network toxicology and molecular docking strategy: A Case Study of Aflatoxin B1

Chu, Z.-Y.; Zi, X.-J.

10.1101/2024.01.10.574998 — pharmacology and toxicology — Posted on 2024-01-12

3050 Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells

Reinecke, J. B.; Gross, A. C.; Cam, M.; Jimenez Garcia, L.; Cannon, M. V.; Dries, R.; Gryder, B. E.; Roberts, R. D.

10.1101/2024.01.10.575008 — cancer biology — Posted on 2024-01-12

3051 Poincare and SimBio: a versatile and extensible Python ecosystem for modeling systems.

Silberberg, M.; Hermjakob, H.; Malik-Sheriff, R. S.; Grecco, H. E.

10.1101/2024.01.10.574883 — bioinformatics — Posted on 2024-01-12

3052 Timing matters: A meta-analysis on the dynamic effect of stress on salivary immunoglobulin

Seizer, L.; Stasielowicz, L.; Loechner, J.

10.1101/2024.01.10.575001 — immunology — Posted on 2024-01-12

3053 Dual DNA/RNA-binding factor regulates dynamics of hnRNP splicing condensates

Ray, M.; Zaborowsky, J.; Mahableshwarkar, P.; Vaidyanathan, S.; Shum, J.; Viswanathan, R.; Huang, A.; Wang, S.-H.; Johnson, V.; Wake, N.; Conard, A. M.; Conicella, A. E.; Puterbaugh, R.; Fawzi, N. L.; Larschan, E.

10.1101/2024.01.11.575216 — genomics — Posted on 2024-01-12

3054 Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease

Zhang, K.; Eldin, P.; Ciesla, J. H.; Briant, L.; Lentini, J. M.; Ramos, J.; Cobb, J.; Munger, J.; Fu, D.

10.1101/2023.02.10.527147 — molecular biology — Posted on 2024-01-12

3055 A system-wide analysis of lipid transfer proteins delineates lipid mobility in human cells

Titeca, K.; Chiapparino, A.; Turei, D.; Zukowska, J.; van Ek, L.; Moqadam, M.; Triana, S.; Nielsen, I. O.; Moller Foged, M.; Gehin, C.; Maeda, K.; Alexandrov, T.; Saez-Rodriguez, J.; Reuter, N.; Hennrich, M. L.; Gavin, A.-C.

10.1101/2023.12.21.572821 — biochemistry — Posted on 2024-01-12

3056 Genetic legacies of mega-landslides: cycles of isolation and contact across flank collapses in an oceanic island

Noguerales, V.; Arjona, Y.; Garcia-Olivares, V.; Machado, A.; Lopez, H.; Patino, J.; Emerson, B. C.

10.1101/2024.01.10.574994 — evolutionary biology — Posted on 2024-01-12

3057 Polygenic architecture of flowering time and its relationship with local environments in the grass Brachypodium distachyon.

Minadakis, N.; Kaderli, L.; Horvath, R.; Xu, W.; Thieme, M.; Woods, D. P.; Roulin, A. C.

10.1101/2023.07.11.548268 — evolutionary biology — Posted on 2024-01-12

3058 Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer

Do, C.; Jiang, G.; Katsifis, C. C.; Narducci, D. N.; Yang, J.; Cova, G.; Sakellaropoulos, T.; Vidal, R.; Lhoumaud, P.; Fara Regis, F.; Kakabadze, N.; Nora, E. P.; Noyes, M.; Chen, X.; Hansen, A. S.; Skok, J. A.

10.1101/2024.01.11.575070 — molecular biology — Posted on 2024-01-12

3059 A robust set of qPCR methods to evaluate adulteration in major spices and herbs

Behr, M.; Garlant, L.; Pietretti, D.; Pellegrin, C.; Lievens, A.; Boix-Sanfeliu, A.; Maquet, A.; Alvarellos, L.

10.1101/2024.01.11.575163 — molecular biology — Posted on 2024-01-12

3060 Predicting brain age across the adult lifespan with spontaneous oscillations and functional coupling in resting brain networks captured with magnetoencephalography

Hardy, S.; Roberts, G.; Ventresca, M.; Dunkley, B. T.

10.1101/2024.01.10.574995 — neuroscience — Posted on 2024-01-12

3061 Comparative transcriptomics of seed nourishing tissues: uncovering conserved and divergent pathways in seed plants

Florez-Rueda, A. M.; Miguel, C. M.; Figueiredo, D. D.

10.1101/2023.11.30.569347 — plant biology — Posted on 2024-01-12

3062 Glycolytic oscillations under periodic drivings

Kim, P.; Hyeon, C.

10.1101/2023.10.08.561464 — biophysics — Posted on 2024-01-12

3063 Kinases in motion: impact of protein and small molecule interactions on kinase conformations

Kugler, V.; Schwaighofer, S.; Feichtner, A.; Enzler, F.; Fleischmann, J.; Strich, S.; Schwarz, S.; Wilson, R.; Tschaikner, P.; Troppmair, J.; Sexl, V.; Meier, P.; Kaserer, T.; Stefan, E.

10.1101/2024.01.11.575270 — biochemistry — Posted on 2024-01-12

3064 Nucleocytoplasmic transport senses mechanics independently of cell density in cell monolayers.

Granero-Moya, I.; Belthier, G.; Groenen, B.; Molina, M.; Gonzalez, M.; Trepat, X.; van Rheenen, J.; Andreu, I.; Roca-Cusachs, P.

10.1101/2024.01.11.575167 — cell biology — Posted on 2024-01-12

3065 Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection

Reynolds, M. B.; Klein, B.; McFadden, M. J.; Judge, N. K.; Navarrete, H. E.; Michmerhuizen, B. C.; Awad, D.; Schultz, T. L.; Harms, P. W.; Zhang, L.; O'Meara, T. R.; Sexton, J. Z.; Lyssiotis, C. A.; Kahlenberg, J. M.; O'Riordan, M. X.

10.1101/2024.01.10.575104 — immunology — Posted on 2024-01-12

3066 Novel Mechanisms of Strigolactone-Induced DWARF14 Degradation in Arabidopsis thaliana

Sanchez Martin-Fontecha, E.; Cardinale, F.; Bürger, M.; Prandi, C.; Cubas, P.

10.1101/2024.01.10.574527 — plant biology — Posted on 2024-01-12

3067 Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish

Massoz, L.; Bergemann, D.; Lavergne, A.; Reynders, C.; Desiront, C.; Goossens, C.; Flasse, L.; Peers, B.; Voz, M.; Manfroid, I.

10.1101/2023.06.05.543680 — developmental biology — Posted on 2024-01-12

3068 Deubiquitinating enzyme mutagenesis screens identify a USP43 driven HIF-1 transcriptional response

Pauzaite, T.; Wit, N.; Seear, R. V.; Nathan, J. A.

10.1101/2024.01.10.574971 — cell biology — Posted on 2024-01-12

3069 Hypothalamic representation of the imminence of predator threat detected by the vomeronasal organ in mice

Nguyen, Q. A. T.; Rocha, A.; Yamashita, Y.; Chhor, R.; Stadler, C.; Pontrello, C.; Haga-Yamanaka, S.

10.1101/2023.09.27.559655 — neuroscience — Posted on 2024-01-12

3070 Feedforward circuits enable modality-specific control of cortical inhibition during behavioral state transitions.

De Brito Van Velze, M.; Dhanasobhon, D.; Martinez, M.; Morabito, A.; Berthaux, E.; Martins Pinho, C.; Rebola, N.; Zerlaut, Y.

10.1101/2024.01.10.574973 — neuroscience — Posted on 2024-01-12

3071 D--hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.

Kula, B.; Antal, B.; Weistuch, C.; Gackiere, F.; Barre, A.; Velado, V.; Hubbard, J. M.; Kukley, M.; Mujica-Parodi, L. R.; Smith, N. A.

10.1101/2023.08.23.554428 — neuroscience — Posted on 2024-01-12

3072 Acetylcholine release from basal forebrain promotes cortical synaptic plasticity via somatostatin interneurons

Zhao, X.; Zhang, Y. E.; Yang, L.; Yang, Y.

10.1101/2023.07.05.547662 — neuroscience — Posted on 2024-01-12

3073 Annexin and calcium-regulated priming of legume root cells for endosymbiotic infection

Guillory, A.; Fournier, J.; Kelner, A.; Hobecker, K.; Auriac, M.-C.; Frances, L.; Delers, A.; Le Ru, A.; Keller, J.; Delaux, P.-M.; Gutjahr, C.; Frei Dit Frey, N.; de Carvalho-Niebel, F.

10.1101/2024.01.10.574854 — plant biology — Posted on 2024-01-12

3074 CEP signaling coordinates plant immunity with nitrogen status

Rzemieniewski, J.; Leicher, H.; Lee, H. K.; Broyart, C.; Nayem, S.; Wiese, C.; Maroschek, J.; Camgoez, Z.; Olsson Lalun, V.; Djordjevic, M. A.; Vlot, A. C.; Hueckelhoven, R.; Santiago, J.; Stegmann, M.

10.1101/2022.12.20.521212 — plant biology — Posted on 2024-01-12

3075 Enhanced PI3K/Akt Signaling in Response to p85α Loss is Regulated by Endosomal PI3Kα and PI3P

Thapa, N.; Chen, M.; Cryns, V. L.; Anderson, R. A.

10.1101/2024.01.10.575035 — cell biology — Posted on 2024-01-12

3076 MPSeqM, a tool combining multiplex PCR and high-throughput sequencing to study the polymorphism of eight Leptosphaeria maculans avirulence genes and its application to field surveys in France

Gautier, A.; Laval, V.; Balesdent, M.-H.

10.1101/2023.10.06.561155 — molecular biology — Posted on 2024-01-12

3077 Negative Synergistic Effects of Drought and Heat During Flowering and Seed Setting in Soybean

Poudel, S.; Vennam, R. R.; V. Sankarapillai, L.; Liu, J.; Reddy, K. R.; Wijewardane, N. K.; Mukhtar, M. S.; Bheemanahalli, R.

10.1101/2024.01.10.575108 — plant biology — Posted on 2024-01-11

3078 The Zymoseptoria tritici avirulence factor AvrStb6 accumulates in hyphae close to stomata and triggers a wheat defense response hindering fungal penetration

Alassimone, J.; Praz, C.; Lorrain, C.; de Francesco, A.; Carrasco-Lopez, C.; Faino, L.; Meile, L.; Sanchez-Vallet, A.

10.1101/2024.01.11.575168 — plant biology — Posted on 2024-01-11

3079 NEUROG2 regulates a human-specific neurodevelopmental gene regulatory program

Chinchalongporn, V.; Vasan, L.; Saleh, F.; Zinyk, D.; Ghazale, H.; Oproescu, A.-M.; Patel, S.; Rozak, M.; Amemiya, Y.; Han, S.; Moffat, A.; Black, S. E.; McLaurin, J.; Near, J.; Seth, A.; Goubran, M.; Reiner, O.; Okawa, S.; Schuurmans, C.

10.1101/2024.01.11.575174 — developmental biology — Posted on 2024-01-11

3080 Epigenetic priming of embryonic lineages in the mammalian epiblast

Sendra, M.; McDole, K.; Jimenez-Carretero, D.; de Dios-Hourcade, J.; Temino Valbuena, S.; Raiola, M.; Guignard, L.; Keller, P. J.; Sanchez-Cabo, F.; Dominguez, J. N.; Torres, M.

10.1101/2024.01.11.575188 — developmental biology — Posted on 2024-01-11

3081 SAX-7/L1CAM acts with the adherens junction proteins MAGI-1, HMR-1/Cadherin, and AFD-1/Afadin to promote glial-mediated dendrite extension

Cebul, E.; Marivin, A.; Wexler, L.; Perrat, P.; Benard, C. Y.; Garcia-Marcos, M. G.; Heiman, M. G.

10.1101/2024.01.11.575259 — developmental biology — Posted on 2024-01-11

3082 Symmetrically fated progenitors dynamically accommodate tissue maintenance in the esophagus.

Grommisch, D.; Wang, M.; Eenjes, E.; Svetlicic, M.; Deng, Q.; Giselsson, P.; Genander, M.

10.1101/2024.01.11.575258 — cell biology — Posted on 2024-01-11

3083 Visualizing Mitochondrial Heme Flow through GAPDH to Targets in Living Cells and its Regulation by NO

Biswas, P.; Palazzo, J.; Schlanger, S.; Jayaram, D. T.; Islam, S.; Page, R. C.; Stuehr, D. J.

10.1101/2024.01.10.575067 — cell biology — Posted on 2024-01-11

3084 Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation

Miao, Y.; Du, Y.; Wang, B.; Liang, J.; Liang, Y.; Dang, S.; Liu, J.; Li, D.; He, K.; Ding, M.

10.1101/2024.01.10.575034 — cell biology — Posted on 2024-01-11

3085 Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy to treat murine liver diseases

Smith, A. R.; Rizvi, F.; Everton, E.; Adeagbo, A.; Wu, S.; Tam, Y.; Muramatsu, H.; Pardi, N.; Weissman, D.; Gouon-Evans, V.

10.1101/2024.01.11.575286 — cell biology — Posted on 2024-01-11

3086 Generation of systemic rabbit chimeras via Induced Pluripotent Stem Cells Reprogrammed with KLF2, ERAS, and PRMT6

Perold, F.; Pham, H.-T.; Pijoff, Y.; Doerflinger, N.; Rival-Gervier, S.; Moulin, A.; Jouneau, L.; Pain, B.; Joly, T.; Duranthon, V.; Afanassieff, M.; Savatier, P.; Beaujean, N.

10.1101/2024.01.10.575048 — cell biology — Posted on 2024-01-11

3087 Evaluation of the efficacy of a full-spectrum medicinal cannabis plant extract with less than 0.3% Delta9-tetrahydrocannabinol in in vitro models of inflammation and excitotoxicity

Ross-Munro, E.; Isikgel, E.; Fleiss, B.

10.1101/2024.01.10.575133 — cell biology — Posted on 2024-01-11

3088 Structure, interaction, and nervous connectivity of beta cell primary cilia

Müller, A.; Klena, N.; Pang, S.; Garcia, L. E. G.; Sulaymankhil, D.; Topcheva, O.; Seliskar, M.; Mziaut, H.; Schöniger, E.; Friedland, D.; Kipke, N.; Kretschmar, S.; Münster, C.; Weitz, J.; Distler, M.; Kurth, T.; Schmidt, D.; Hess, H. F.; Xu, C. S.; Pigino, G.; Solimena, M.

10.1101/2023.12.01.568979 — cell biology — Posted on 2024-01-11

3089 Detection of Fluorescent Protein Mechanical Switching in Cellulo

Shoyer, T. C.; Collins, K. L.; Ham, T. R.; Blanchard, A. T.; Malavade, J. N.; West, J. L.; Hoffman, B. D.

10.1101/2024.01.10.575065 — cell biology — Posted on 2024-01-11

3090 Starvation resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity

Pozo-Morales, M.; Cobham, A. E.; Centola, C.; McKinney, M. C.; Liu, P.; Perazzolo, C.; Lefort, A.; Libert, F.; Bai, H.; Rohner, N.; Singh, S. P.

10.1101/2024.01.10.574986 — cell biology — Posted on 2024-01-11

3091 Dietary super-doses of cholecalciferol in aged laying hens illustrates limitation of 24,25-dihydroxycholecalciferol conversion

Warren, M. F.; Pitman, P. M.; Hodgson, D. D.; Thompson, N. C.; Livingston, K. A.

10.1101/2021.10.14.464328 — physiology — Posted on 2024-01-11

3092 Spatial Transcriptomics Sequencing of Mouse Liver at 2 Micron Resolution Using a Novel Spatial DNA Chip

Ding, X.; Hoff, K.; Swaminathan, R.; Pollom, S.; Huang, T.; Li, X.; Zhou, G.; Bai, Z.; Yu, S.; Xia, Z.; Koutrouli, M.; Jensen, L. J.; Crnogorac, F.; Crnogorac, F.; Yu, S.; McGall, G.; Edwards, J.; Zhou, W.

10.1101/2024.01.08.574734 — genomics — Posted on 2024-01-11

3093 Multiple focal pulvinar projection fields in the macaque cortex

Froesel, M.; Clavagnier, S.; Goudard, Q.; Zhu, Q.; Vanduffel, W.; Ben Hamed, S.

10.1101/2023.11.20.567885 — neuroscience — Posted on 2024-01-11

3094 Polarised subcellular activation of ROPs by specific ROPGEFs drives pollen germination in Arabidopsis thaliana

Bouatta, A. M.; Lepper, A.; Denninger, P.

10.1101/2024.01.11.575165 — plant biology — Posted on 2024-01-11

3095 RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells.

Siruvallur Murali, V.; Rajendran, D.; Isogai, T.; DeBerardinis, R. J.; Danuser, G.

10.1101/2024.01.09.574940 — cancer biology — Posted on 2024-01-11

3096 Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

Yue, F.; Ku, A. T.; Stevens, P.; Michalski, M.; Jiang, W.; Tu, J.; Shi, Z.; Dou, Y.; Wang, Y.; Feng, X.-H.; Hostetter, G.; Wu, X.; Huang, S.; Shroyer, N.; Zhang, B.; Williams, B.; Liu, Q.; Lin, X.; Li, Y.

10.1101/2024.01.10.574969 — cancer biology — Posted on 2024-01-11

3097 Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells

Tarrado-Castellarnau, M.; Foguet, C.; Tarrago-Celada, J.; Palobart, M.; Hernandez-Carro, C.; Perarnau, J.; Zodda, E.; Polat, I. H.; Marin, S.; Suarez-Bonnet, A.; Lozano, J. J.; Yuneva, M.; Thomson, T. M.; Cascante, M.

10.1101/2024.01.04.574237 — cancer biology — Posted on 2024-01-11

3098 Liver cancer initiation is dependent on metabolic zonation but decoupled from premalignant clonal expansion

Chung, A.; Guo, J.; Wang, Y.; Jia, Y.; Corbitt, N.; Li, L.; Wei, Y.; Zhu, M.; Wang, Z.; Guo, H.; Gopal, P.; Xiao, G.; Wang, T.; Zhu, H.

10.1101/2024.01.10.575013 — cancer biology — Posted on 2024-01-11

3099 Amyloid Morphology is Encoded in H-bonds and Electrostatics Interactions Ruling Protein Phase Separation

Lenton, S. J.; Chaaban, H.; Khaled, M.; van de Weert, M.; Strodel, B.; Fodera, V.

10.1101/2024.01.10.574993 — biophysics — Posted on 2024-01-11

3100 The Time-Course of Food Representation in the Human Brain

Moerel, D.; Psihoyos, J.; Carlson, T. A.

10.1101/2023.06.06.543985 — neuroscience — Posted on 2024-01-11

3101 Single nuclei multiomics reveals the drought-driven gene regulatory atlas in Arabidopsis

Liu, J.; Majeed, A.; Kumar, N.; Pajerowska-Mukhtar, K. M.; Mukhtar, M. S.

10.1101/2024.01.11.575118 — plant biology — Posted on 2024-01-11

3102 Unraveling Glioblastoma Heterogeneity: Introducing SP2G Method for Identifying Invasive Sub-Populations

Crestani, M.; Kakogiannos, N.; Iannelli, F.; Dini, T.; Maderna, C.; Giannotta, M.; Pelicci, G.; Maiuri, P.; Monzo, P.; Gauthier, N.

10.1101/2024.01.10.574982 — biophysics — Posted on 2024-01-11

3103 Peptidyl-tRNA hydrolysis rate influences the efficiency of nonsense-mediated mRNA decay

Kolakada, D.; Fu, R.; Biziaev, N.; Shuvalov, A.; Lore, M.; Campbell, A. E.; Cortazar, M. A.; Sajek, M. P.; Hesselberth, J. R.; Mukherjee, N.; Alkalaeva, E.; Jagannathan, S.

10.1101/2024.01.10.575080 — molecular biology — Posted on 2024-01-11

3104 Transient RNA structures underlie highly pathogenic avian influenza virus genesis

Funk, M.; Spronken, M. I.; Bestebroer, T. M.; de Bruin, A. C. M.; Gultyaev, A. P.; Fouchier, R. A. M.; te Velthuis, A. J. W.; Richard, M.

10.1101/2024.01.11.574333 — microbiology — Posted on 2024-01-11

3105 Murine norovirus mutants adapted to replicate in human cells reveal a post-entry restriction

Budicini, M. R.; Rodriguez-Irizarry, V. J.; Maples, R. W.; Pfeiffer, J. K.

10.1101/2024.01.11.575274 — microbiology — Posted on 2024-01-11

3106 Pseudo-spectral angle mapping for automated pixel-level analysis of highly multiplexed tissue image data

Durkee, M. S.; Ai, J.; Casella, G.; Cao, T.; Chang, A.; Halper-Stromberg, A.; Jabri, B.; Clark, M. R.; Giger, M. L.

10.1101/2024.01.09.574920 — bioinformatics — Posted on 2024-01-11

3107 scATAnno: Automated Cell Type Annotation for single-cell ATAC Sequencing Data

Jiang, Y.; Hu, Z.; Lynch, A. W.; Jiang, J.; Zhu, A.; Zhang, Y.; Xie, Y.; Li, R.; Zhou, N.; Meyer, C. A.; Cejas, P.; Brown, M.; Long, H. W.; Qiu, X.

10.1101/2023.06.01.543296 — bioinformatics — Posted on 2024-01-11

3108 Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them

Dalwani, S.; Metz, A.; Huschmann, F. U.; Weiss, M. S.; Wierenga, R. K.; Venkatesan, R.

10.1101/2024.01.11.575214 — biochemistry — Posted on 2024-01-11

3109 A Phased, Chromosome-scale Genome for Malus domestica 'WA 38'

Zhang, H.; Eaker, A.; Ko, I.; Haney, S.; Khuu, N.; Ryan, K.; Appleby, A.; Hoffmann, B.; Landis, H.; Pierro, K.; Willsea, N.; Hargarten, H.; Yocca, A.; Harkess, A.; Honaas, L.; Ficklin, S.

10.1101/2024.01.10.574953 — genomics — Posted on 2024-01-11

3110 Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage

Jones, E. F.; Howton, T. C.; Flanary, V. L.; Clark, A. D.; Lasseigne, B. N.

10.1101/2024.01.11.575219 — genomics — Posted on 2024-01-11

3111 A framework evaluating the utility of multi-gene, multi-disease population-based panel testing that accounts for uncertainty in penetrance estimates

Liang, J. W.; Christensen, K. D.; Green, R. C.; Kraft, P.

10.1101/2022.08.10.503415 — genetics — Posted on 2024-01-11

3112 RNA polymerase II-mediated rDNA transcription mediates rDNA copy number expansion in Drosophila

Watase, G. J.; Yamashita, Y. M.

10.1101/2024.01.11.575146 — genetics — Posted on 2024-01-11

3113 Single-step generation of homozygous knock-out/knock-in individuals in an extremotolerant parthenogenetic tardigrade using DIPA-CRISPR

Kondo, K.; Tanaka, A.; Kunieda, T.

10.1101/2024.01.10.575120 — genetics — Posted on 2024-01-11

3114 Effects of selfing on the evolution of sexual reproduction

Xu, K.

10.1101/2023.03.07.531539 — evolutionary biology — Posted on 2024-01-11

3115 Beyond the (geometric) mean: stochastic models undermine deterministic predictions of bet hedger evolution

Weissman, M. R.; Raynes, Y.; Weinreich, D. M.

10.1101/2023.07.11.548608 — evolutionary biology — Posted on 2024-01-11

3116 Size spectra in freshwater streams are consistent across temperature and resource supply

Gjoni, V.; Pomeranz, J. P. F.; Junker, J. R.; Wesner, J. S.

10.1101/2024.01.09.574822 — ecology — Posted on 2024-01-11

3117 Orthogonal targeting of SAC1 to mitochondria implicates ORP2 as a major player in PM PI4P turnover

Doyle, C. P.; Rectenwald, A.; Timple, L.; Hammond, G. R.

10.1101/2023.08.28.555163 — cell biology — Posted on 2024-01-11

3118 Discretised flux balance analysis for reaction-diffusion simulation of single-cell metabolism

Chew, Y. H.; Spill, F.

10.1101/2023.08.01.551453 — cell biology — Posted on 2024-01-11

3119 Marine Bacteria Alteromonas spp. Require UDP-glucose-4-epimerase for Aggregation and Production of Sticky Exopolymer

Robertson, J. M.; Garza, E. A.; Stubbusch, A. K.; Dupont, C. L.; Hwa, T.; Held, N. A.

10.1101/2024.01.11.575244 — microbiology — Posted on 2024-01-11

3120 Dopamine lesions alter the striatal encoding of single-limb gait

Yang, L.; Singla, D.; Wu, A. K.; Cross, K. A.; Masmanidis, S. C.

10.1101/2023.10.06.561216 — neuroscience — Posted on 2024-01-11

3121 Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the AD-BXD Mouse Population

Saul, M. C.; Litkowski, E. M.; Hadad, N.; Dunn, A. R.; Boas, S. M.; Willcox, J. A. L.; Robbins, J. E.; Wu, Y.; Philip, V. M.; Merrihew, G. E.; Park, J.; De Jager, P. L.; Bridges, D. E.; Menon, V.; Bennett, D. A.; Hohman, T. J.; MacCoss, M. J.; Kaczorowski, C. C.

10.1101/2024.01.09.574219 — neuroscience — Posted on 2024-01-11

3122 Diverse GABA signaling in the inner retina enables spatiotemporal coding

Matsumoto, A.; Morris, J.; Looger, L. L.; Yonehara, K.

10.1101/2024.01.09.574952 — neuroscience — Posted on 2024-01-11

3123 Unraveling the oscillatory dynamics of mRNA metabolism and chromatin accessibility during the cell cycle through integration of single-cell multiomic data

Nariya, M. K.; Santiago-Algarra, D.; Tassy, O.; Cerciat, M.; Ye, T.; Riba, A.; Molina, N.

10.1101/2024.01.11.575159 — systems biology — Posted on 2024-01-11

3124 Loss of the brain-liver axis prevents hepatic steatosis in mice.

JO, y.-h.; Hwang, J.; Okada, J.; Liu, L.; Pessin, J. E.; Schwartz, G. J.

10.1101/2023.11.03.565494 — physiology — Posted on 2024-01-11

3125 Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3

Shiraishi, N.; Konuma, T.; Chiba, Y.; Hokazono, S.; Islam, M. H.; Nakanishi, M.; Nishiyama, A.; Arita, K.

10.1101/2024.01.11.575164 — biochemistry — Posted on 2024-01-11

3126 Meta-metabolome ecology reveals that geochemistry and microbial functional potential are linked to organic matter development across seven rivers

Danczak, R. E.; Goldman, A. E.; Borton, M. A.; Chu, R. K.; Toyoda, J. G.; Garayburu-Caruso, V. A.; Graham, E. B.; Morad, J. W.; Renteria, L.; Hager, J. R.; Arnon, S.; Brooks, S.; Bar-Zeev, E.; Jones, M.; Jones, N.; Lewandowski, J.; Meile, C.; Muller, B. M.; Schalles, J.; Schulz, H.; Ward, A.; Stegen, J. C.

10.1101/2024.01.10.575030 — ecology — Posted on 2024-01-11

3127 A temporal map of division, chromatin modification, and identity specification in the regenerating Arabidopsis root.

Rahni, R.; Guillotin, B.; Lee, L. R.; Birnbaum, K. D.

10.1101/2024.01.09.574680 — developmental biology — Posted on 2024-01-11

3128 Impact of Plasmodium falciparum patient-derived isolates on brain endothelium in vitro

Askonas, C. F.; Storm, J.; Camarda, G.; Craig, A.; Pain, A.

10.1101/2024.01.11.575088 — cell biology — Posted on 2024-01-11

3129 Assessing complex member composition and insecticide resistance status of Anopheles gambiae s.l. in three coastal health districts of Cote d'Ivoire.

Ives, K. J. K.; Constant, E. A. V.; Julien, Z. B. Z.; Ruth, K. A. M.; Alain, K. K. Y.; Firmain, Y. N.; Constant, G. N. G.; Malone, D.; Benjamin, K. G.

10.1101/2024.01.10.575138 — molecular biology — Posted on 2024-01-11

3130 Increased mitochondrial transcription initiation does not promote oxidative phosphorylation

Miranda, M.; Mesaros, A.; Kuznetsova, I.; Purrio, M.; Perard, L.; Filipovska, A.; Mourier, A.; Larsson, N.-G.; Kuhl, I.

10.1101/2024.01.11.575236 — molecular biology — Posted on 2024-01-11

3131 A dual histone code specifies the binding of heterochromatin protein Rhino to a subset of piRNA source loci

Akkouche, A.; Kneuss, E.; Bornelöv, S.; Renaud, Y.; Eastwood, E. L.; van Lopik, J.; Gueguen, N.; Jiang, M.; Creixell, P.; Maupetit-Mehouas, S.; Nicholson, B. C.; Brasset, E.; Hannon, G. J.

10.1101/2024.01.11.575256 — molecular biology — Posted on 2024-01-11

3132 Effects of different feeding methods on serum biochemical indexes, metabolic indexes, immune indexes, and intestinal microorganisms of Nanjiang yellow goats

ANWAR, A.; Luo, Y.; Pan, C.; Shi, H.; Mustafa, S. B.; Chen, Y.; Zhang, Z.; Li, J.; Zhu, J.; Zhao, W.

10.1101/2024.01.10.575136 — microbiology — Posted on 2024-01-11

3133 Detection of naturally acquired, strain-transcending antibodies against rosetting Plasmodium falciparum strains in humans

Rowe, A.; McLean, F.; Azasi, Y.; Sutherland, C.; Toboh, E.; Ansong, D.; Agbenyega, T.; Awandare, G. A.

10.1101/2024.01.11.575252 — microbiology — Posted on 2024-01-11

3134 Stable isotopes and nanoSIMS single-cell imaging reveals soil plastisphere colonizers able to assimilate sulfamethoxazole

Xiang, Q.; Stryhanyuk, H.; Schmidt, M.; Richnow, H. H.; Zhu, Y.; Cui, L.; Musat, N.

10.1101/2024.01.11.575183 — microbiology — Posted on 2024-01-11

3135 Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae

Perez, A. J.; Lamanna, M. M.; Bruce, K. E.; Touraev, M. A.; Page, J. E.; Shaw, S. L.; Tsui, H.-C. T.; Winkler, M. E.

10.1101/2024.01.10.575112 — microbiology — Posted on 2024-01-11

3136 Red blood cell dynamics during malaria infection violate the assumptions of mathematical models of infection dynamics

Peters, M. A. E.; King, A. A.; Wale, N.

10.1101/2024.01.10.575051 — microbiology — Posted on 2024-01-11

3137 Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

Podkowik, M.; Perault, A. I.; Putzel, G.; Pountain, A.; Kim, J.; DuMont, A.; Zwack, E.; Ulrich, R. J.; Karagounis, T. K.; Zhou, C.; Haag, A. F.; Shenderovich, J.; Wasserman, G. A.; Kwon, J.; Chen, J.; Richardson, A. R.; Weiser, J. N.; Nowosad, C. R.; Lun, D. S.; Zhao, X.; Parker, D.; Pironti, A.; Drlica, K. N.; Yanai, I.; Torres, V. J.; Shopsin, B.

10.1101/2023.06.08.544038 — microbiology — Posted on 2024-01-11

3138 Aspergillus-mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype, a process that can be targeted via antifungal therapeutics.

Houlder, E. L.; Gago, S.; Vere, G.; Conn, D.; Khan, S.; Thomson, D.; Shepherd, M.; Lebedinec, R.; Brown, G. D.; Bromley, M.; MacDonald, A. S.; Cook, P. C.

10.1101/2024.01.11.575032 — immunology — Posted on 2024-01-11

3139 Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation

Zollner, H. J.; Davies-Jenkins, C. B.; Simicic, D. B.; Tal, A.; Sulam, J.; Oeltzschner, G.

10.1101/2023.11.01.565164 — neuroscience — Posted on 2024-01-11

3140 Sex differences in social synchronization of conditioned fear.

Ito, W.; Morozov, A.

10.1101/2022.10.10.511569 — neuroscience — Posted on 2024-01-11

3141 Human Brain Mapping of Homotopic Functional Affinity

Chen, L.-Z.; Zuo, X.-N.

10.1101/2024.01.09.574929 — neuroscience — Posted on 2024-01-11

3142 Beyond Prior Belief and Volatility: The Distinct Iterative Prior Updating Process in ASD

Shi, Z.; Allenmark, F.; Theisinger, L.; Pistorius, R.; Glasauer, S.; Mueller, H. J.; Falter-Wagner, C.

10.1101/2022.01.21.477218 — neuroscience — Posted on 2024-01-11

3143 Raw signal segmentation for estimating RNA modifications and structures from Nanopore direct RNA sequencing data

Cheng, G.; Vehtari, A.; Cheng, L.

10.1101/2024.01.11.575207 — bioinformatics — Posted on 2024-01-11

3144 Novel Gurmarin-like Peptides from Gymnema sylvestre and their Interactions with the Sweet Taste Receptor T1R2/T1R3

Maaroufi, H.

10.1101/2023.08.28.555239 — bioinformatics — Posted on 2024-01-11

3145 The Cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains

Vitoria Gomes, M.; landwerlin, P.; Diebold-Durand, M.-L.; Shaik, T. B.; Durand, A.; Troesch, E.; Weber, C.; Brillet, K.; Lemee, M.; Decroos, C.; Dulac, L.; Antony, P.; Watrin, E.; Ennifar, E.; Golzio, C.; Romier, C.

10.1101/2022.06.24.497451 — biochemistry — Posted on 2024-01-11

3146 Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase

Qayyum, M. Z.; Imashimizu, M.; Leanca, M.; Vishwakarma, R. K.; Riaz-Bradley, A.; Yuzenkova, Y.; Murakami, K.

10.1101/2024.01.11.575193 — biochemistry — Posted on 2024-01-11

3147 Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High Fat, High Fructose, High Cholesterol Diet Mouse Model

Ohene-Marfo, P.; Nguyen, H. V. M.; Mohammed, S.; Thadathil, N.; Tran, A.; Nicklas, E. H.; Wang, D.; Selvarani, R.; Farriester, J.; Varshney, R.; Kinter, M.; Richardson, A.; Rudolph, M.; Deepa, S. S.

10.1101/2024.01.10.575102 — biochemistry — Posted on 2024-01-11

3148 NGN3 oscillatory expression controls the timing of human pancreatic endocrine differentiation

Miller, A.; Biga, V.; Rowntree, A.; Chhatriwala, M.; Woods, F.; Marinopoulou, E.; Kamath, A.; Vallier, L.; Papalopulu, N.

10.1101/2024.01.10.574974 — developmental biology — Posted on 2024-01-11

3149 The C. elegans proteome response to two protective Pseudomonas symbionts

Pees, B.; Peters, L.; Treitz, C.; Hamerich, I. K.; Kissoyan, K. A.; Tholey, A.; Dierking, K.

10.1101/2023.03.22.533766 — molecular biology — Posted on 2024-01-11

3150 A dynamic subpopulation of CRISPR-Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage

Stoltzfus, M. J.; Workman, R. E.; Keith, N. C.; Modell, J. W.

10.1101/2024.01.11.575229 — microbiology — Posted on 2024-01-11

3151 RNase-mediated reprogramming of Yersinia virulence

Meyer, I.; Volk, M.; Salto, I.; Moesser, T.; Herbrüggen, A.-S.; Rohde, M.; Beckstette, M.; Heroven, A. K.; Dersch, P.

10.1101/2024.01.11.575149 — microbiology — Posted on 2024-01-11

3152 Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

Bennett, J. M.; Narwal, S. K.; Kabeche, S.; Abegg, D.; Hackett, F.; Yeo, T.; Li, V.; Muir, R. K.; Faucher, F. F.; Lovell, S.; Blackman, M.; Adibekian, A.; Yeh, E.; Fidock, D. A.; Bogyo, M.

10.1101/2024.01.11.575224 — microbiology — Posted on 2024-01-11

3153 Characterization of the growth promotion and defense enhancement of soybean plants driven by seed treatment of multiple soybean-associated beneficial bacteria

Calderon, R. B.; Ontoy, J. C.; Barphagha, I.; Ham, J. H.

10.1101/2024.01.10.575074 — microbiology — Posted on 2024-01-11

3154 Ability of mycobacterial pathogens to establish a persistent infection is lost by deletion of a single gene, rel, regulator of the stringent response

Mahmoud, A. H. A.; Abdellrazeq, G. S.; Fry, L. M.; Schneider, D. A.; Attreed, S.; Burton, L.; Sangewar, N.; Mwangi, W.; deSouza, C.; Hulubei, V.; Davis, W. C.; Park, K. T.

10.1101/2024.01.10.575042 — immunology — Posted on 2024-01-11

3155 TCR-engineered T-cells directed against Ropporin-1 constitute a safe and effective treatment for triple-negative breast cancer in near-clinical models

Kortleve, D.; Hammerl, D.; van Brakel, M.; Wijers, R.; Roelofs, D.; Kroese, K.; Timmermans, M.; Liao, C.-Y.; Trapman-Jansen, A.; Foekens, R.; Michaux, J.; de Beijer, M.; Buschow, S. I.; Demmers, J. A.; Kok, M.; Danen, E. H. J.; Bassani-Sternberg, M.; Martens, J. W.; Abbott, R. J. M.; Debets, R.

10.1101/2024.01.10.574978 — immunology — Posted on 2024-01-11

3156 Whole-cortex simulation reveals spatiotemporal patterns emerging from the interplay of network connectivity and intracellular dynamics

Sun, G.; Hazelden, J.; Kim, R.; Forger, D.

10.1101/2024.01.10.574958 — neuroscience — Posted on 2024-01-11

3157 Emotional prosody modulates visual mental imagery

Huang, W.; Zhang, F.; Zhang, C.; Wang, C.; Zhang, S.; Pu, Y.; Kong, X.-Z.

10.1101/2024.01.10.574936 — neuroscience — Posted on 2024-01-11

3158 Taxonomy and phylogeny of the family Suberitidae (Porifera: Demospongiae) in California

Turner, T. L.; Rouse, G. W.; Weigel, B. L.; Janusson, C.; Lemay, M. A.; Thacker, R. W.

10.1101/2024.01.10.575078 — zoology — Posted on 2024-01-11

3159 APNet, an explainable sparse deep learning model to discover differentially active drivers of severe COVID-19

Gavriilidis, G.; Vasileiou, V.; Dimitsaki, S.; Karakatsoulis, G.; Giannakakis, A.; Pavlopoulos, G.; Psomopoulos, F.

10.1101/2024.01.11.575161 — systems biology — Posted on 2024-01-11

3160 A quantitative description of light-limited cyanobacterial growth using flux balance analysis

Hoeper, R.; Komkova, D.; Zavrel, T.; Steuer, R.

10.1101/2024.01.10.574812 — systems biology — Posted on 2024-01-11

3161 Transcriptome-wide analysis of cell cycle-dependent bursty gene expression from single-cell RNA-seq data using mechanistic model-based inference

Sukys, A.; Grima, R.

10.1101/2024.01.10.574820 — systems biology — Posted on 2024-01-11

3162 Active site remodeling in IDH1 mutants drives distinct kinetic and potential resistance mechanisms

10.1101/2024.01.10.574970 — biochemistry — Posted on 2024-01-11

3163 Origin and diversification of a globally distributed group of parasitic feather lice

Sweet, A.; Dona, J.; Johnson, K. P.

10.1101/2024.01.11.575230 — evolutionary biology — Posted on 2024-01-11

3164 A highly contiguous genome assembly for the Yellow Warbler (Setophaga petechia)

Tsai, W. L. E.; Escalona, M.; Garrett, K. L.; Terrill, R. S.; Sahasrabudhe, R.; Nguyen, O.; Beraut, E.; Seligmann, W.; Harrigan, R. J.; McCormack, J. E.; Alfaro, M. E.; Smith, T. B.; Bay, R. A.

10.1101/2024.01.10.575107 — evolutionary biology — Posted on 2024-01-11

3165 Efficacy of dynamic eigenvalue in anticipating and distinguishing tipping points

Kulkarni, K.; Deb, S.; Dutta, P. S.

10.1101/2024.01.09.574944 — ecology — Posted on 2024-01-11

3166 Partitioning to ordered membrane domains regulates the kinetics of secretory traffic

Castello-Serrano, I.; Heberle, F. A.; Diaz-Rohrer, B.; Ippolito, R.; Shurer, C. R.; Lujan, P.; Campelo, F.; Levental, K. R.; Levental, I.

10.1101/2023.04.18.537395 — cell biology — Posted on 2024-01-11

3167 Rgf1 GEF activity toward Rho1 defines a new actin-dependent signal to determine growth sites independently of microtubules and Tea1

Garcia, P.; Celador, R.; Edreira, T.; Sanchez, Y.

10.1101/2024.01.10.574961 — cell biology — Posted on 2024-01-11

3168 Chemogenetic attenuation of PFC pyramidal neurons restores deficits in recognition memory following adolescent NMDA receptor blockade

Bauminger, H.; Chandran, S. K.; Akirav, I.; Gaisler-Salomon, I.

10.1101/2024.01.10.574791 — neuroscience — Posted on 2024-01-11

3169 DNA methylation patterns in the frontal lobe white matter of multiple system atrophy, Parkinson's disease, and progressive supranuclear palsy: A cross-comparative investigation

Murthy, M.; Fodder, K.; Miki, Y.; Rambarack, N.; De Pablo Fernandez, E.; Mill, J.; Warner, T. T.; Lashley, T.; Bettencourt, C.

10.1101/2024.01.10.574852 — neuroscience — Posted on 2024-01-11

3170 Development of Int-Plex@ binary memory switch system: plant genome modulation driven by large serine-integrases.

de Oliveira, M. A.; Lima, R. N.; Florentino, L. H.; Severo de Almeida, M. M.; Melo, F. L.; Bonnet, R. V.; Lacorte, C.; Rech, E.

10.1101/2024.01.11.575089 — synthetic biology — Posted on 2024-01-11

3171 Novel Mechanisms of Strigolactone-Induced DWARF14 Degradation in Arabidopsis thaliana

Sanchez Martin-Fontecha, E.; Cardinale, F.; Bürger, M.; Prandi, C.; Cubas, P.

10.1101/2024.01.10.574527 — plant biology — Posted on 2024-01-11

3172 Evolution and diversification of the momilactone biosynthetic gene cluster in the genus Oryza

Priego Cubero, S.; Toyomasu, T.; Hasegawa, Y.; Liu, Y.; Nojiri, H.; Okada, K.; Becker, C.

10.1101/2024.01.11.572147 — plant biology — Posted on 2024-01-11

3173 Functional profiling of the male gametophyte-specific promoter fragment of Arabidopsis PIRL6 gene and prediction of cis-regulatory elements

T G, A.; M Shah, J.

10.1101/2024.01.09.574950 — plant biology — Posted on 2024-01-11

3174 Environmentally-informed functional characterization of a plastid diatom metabolic bridge of mitochondrial origin

Dorrell, R. G.; Zhang, Y.; Liang, Y.; Gueguen, N.; Nonoyama, T.; Croteau, D.; Penot, M.; Adiba, S.; Bailleul, B.; Gros, V.; Karlusich, J. J. P.; Zweig, N.; Fernie, A. R.; Jouhet, J.; Marechal, E.; Bowler, C.

10.1101/2022.09.08.507166 — plant biology — Posted on 2024-01-11

3175 Annexin and calcium-regulated priming of legume root cells for endosymbiotic infection

Guillory, A.; Fournier, J.; Kelner, A.; Hobecker, K.; Auriac, M.-C.; Frances, L.; Delers, A.; Le Ru, A.; Keller, J.; Delaux, P.-M.; Gutjahr, C.; Frei Dit Frey, N.; de Carvalho-Niebel, F.

10.1101/2024.01.10.574854 — plant biology — Posted on 2024-01-11

3176 Growth phase-dependent reorganization of cryptophyte photosystem I antennae

Zhang, S.; Si, L.; Su, X.; Li, M.

10.1101/2024.01.10.574992 — plant biology — Posted on 2024-01-11

3177 Analysis of a diverse wheat germplasm panel reveals a highly diverse introgression landscape and provides evidence for inter-homoeolog chromosomal recombination

Heuberger, M.; Bernasconi, Z.; Jung, E.; Herren, G.; Widrig, V.; Keller, B.; Sanchez- Martin, J.; Wicker, T.

10.1101/2024.01.10.574987 — plant biology — Posted on 2024-01-11

3178 The triose phosphate/phosphate translocator exports photosynthetic glyceraldehyde 3-phosphate from chloroplasts to trigger antimicrobial immunity in plants.

Zuo, D.-P.; Wang, B.; Liu, Y.-Z.; Chen, Z.-S.; Hu, R.-J.; He, M.-J.; Zhang, Z.-Y.; Wang, Y.; Han, C.-G.

10.1101/2024.01.10.574840 — plant biology — Posted on 2024-01-11

3179 USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.

Mackay, H. L.; Stone, H. R.; Ellis, K.; Ronson, G.; Starowicz, K.; Garvin, A. J.; Van Eijk, P.; Aitsiankova, A.; Vijayendran, S.; Beesley, J.; Petermann, E.; Brown, E.; Densham, R. M.; Reed, S. H.; Dobbs, F.; Walker, A. K.; Saponaro, M.; Morris, J. R.

10.1101/2024.01.10.574674 — cancer biology — Posted on 2024-01-11

3180 Photoswitchable endocytosis of biomolecular condensates in giant vesicles

Mangiarotti, A.; Aleksanyan, M.; Siri, M.; Lipowsky, R.; Dimova, R.

10.1101/2024.01.10.574984 — biophysics — Posted on 2024-01-11

3181 Cholesterol-Dependent Membrane Deformation by Metastable Viral Capsids Facilitates Entry

Jiao, M.; Danthi, P.; Yu, Y.

10.1101/2024.01.10.575085 — biophysics — Posted on 2024-01-11

3182 Generative modeling of biological shapes and images using a probabilistic α-shape sampler

Winn-Nunez, E. T.; Witt, H.; Bhaskar, D.; Huang, R. Y.; Reichner, J. S.; Wong, I. Y.; Crawford, L.

10.1101/2024.01.09.574919 — bioinformatics — Posted on 2024-01-11

3183 Microenvironment of metastasis reveals key predictors of PD-1 blockade response in renal cell carcinoma

Jeanneret, F.; Bazelle, P.; Schoch, S.; Pillet, C.; Um, I. H.; Bouzit, A.; Evrard, B.; Seffar, E.; Chalmel, F.; Alfaro, J. A.; Pesquita, C.; Zanzotto, F. M.; Stares, M.; Symeonides, S. N.; Laird, A.; Long, J.-A.; Descotes, J. L.; Pflieger, D.; Harrison, D. J.; Filhol, O.; Axelson, H.; Battail, C.

10.1101/2023.07.17.548676 — bioinformatics — Posted on 2024-01-11

3184 Long mounting with repeated copulations in Zygogramma bicolorata: A test of adaptive significance of a curious mating behaviour

Pal, R. S.; Bhowmick, A.; Naik, K.; Nandy, B.

10.1101/2024.01.10.574980 — animal behavior and cognition — Posted on 2024-01-11

3185 Impacts of increasing isolation and environmental variation on Florida Scrub-Jay demography

Summers, J.; Cosgrove, E.; Bowman, R.; Fitzpatrick, J. W.; Chen, N.

10.1101/2024.01.10.575127 — ecology — Posted on 2024-01-11

3186 Macromolecular toolbox to elucidate CLE-RLK binding, signaling and downstream effects

Narasimhan, M.; Jahnke, N.; Kallert, F.; Bahafid, E.; Boehmer, F.; Hartmann, L.; Simon, R. G.

10.1101/2024.01.11.570615 — cell biology — Posted on 2024-01-11

3187 Deubiquitinating enzyme mutagenesis screens identify a USP43 driven HIF-1 transcriptional response

Pauzaite, T.; Wit, N.; Seear, R. V.; Nathan, J. A.

10.1101/2024.01.10.574971 — cell biology — Posted on 2024-01-11

3188 Mechanism and regulation of cargo entry into the Commander recycling pathway

Butkovic, R.; Walker, A. P.; Healy, M. D.; McNally, K. E.; Liu, M.; Kato, K.; Collins, B. M.; Cullen, P. J.

10.1101/2024.01.10.574988 — cell biology — Posted on 2024-01-11

3189 Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface

Avery, E. G.; Haag, L.-M.; McParland, V.; Kedziora, S. M.; Zigra, G. J.; Valdes, D. S.; Kirchner, M.; Popp, O.; Geisberger, S.; Nonn, O.; Karlsen, T. V.; N'Diaye, G.; Yarritu, A.; Bartolomaeus, H.; Bartolomaeus, T. U.; Wimmer, M. I.; Haase, N.; Wilhelm, A.; Gruetz, G.; Tenstad, O.; Wilck, N.; Forslund, S. K.; Klopfleisch, R.; Kuehl, A. A.; Atreya, R.; Kempa, S.; Mertins, P.; Siegmund, B.; TRR241 IBDome Consortium, ; Wiig, H.; Mueller, D. N.

10.1101/2024.01.11.574524 — microbiology — Posted on 2024-01-11

3190 Genotyping of Leptospira spp. in wild rats leads to first time detection of L. kirshneri serovar Mozdok in Serbia

Gajdov, V.; Jokic, G.; Savic, S.; Zekic, M.; Blazic, T.; Rajkovic, M.; Petrovic, T.

10.1101/2024.01.11.575145 — microbiology — Posted on 2024-01-11

3191 An arms race under RIG-I loss: 5'ppp-RNA and its alternative recognition receptor MDA5

Geng, S.; Lv, X.; Zheng, W.; Xu, T.

10.1101/2024.01.10.575132 — immunology — Posted on 2024-01-11

3192 Long-term plasticity induces sparse and specific synaptic changes in a biophysically detailed cortical model

Ecker, A.; Egas Santander, D.; Abdellah, M.; Blanco Alonso, J.; Bolanos-Puchet, S.; Chindemi, G.; Isbister, J. B.; King, J. G.; Kumbhar, P.; Magkanaris, I.; Muller, E. B.; Reimann, M. W.

10.1101/2023.08.07.552264 — neuroscience — Posted on 2024-01-11

3193 Detection and Removal of Hyper-synchronous Artifacts in Massively Parallel Spike Recordings

Oberste-Frielinghaus, J.; Morales-Gregorio, A.; Essink, S.; Kleinjohann, A.; Grun, S.; Ito, J.

10.1101/2024.01.11.575181 — neuroscience — Posted on 2024-01-11

3194 Recurrent connections enable point attractor dynamics and dimensionality reduction in a connectome-constrained model of the insect learning center

Joyce, J.; Norman-Tenazas, R.; Rivlin, P.; Hwang, G. M.; Western, I.; Zhang, K.; Gray-Roncal, W.; Robinson, B.

10.1101/2024.01.10.574960 — neuroscience — Posted on 2024-01-11

3195 A precision medicine approach for HCN1 Developmental and Epileptic Encephalopathy

Bleakley, L. E.; McKenzie, C. E.; Zhao, D.; Soh, M. S.; Spyrou, J.; Forster, I. C.; Bui, B. V.; Reid, C. A.

10.1101/2024.01.09.574555 — neuroscience — Posted on 2024-01-11

3196 Hebbian activity only temporarily stabilizes synaptic transmission at CA3 - CA1 synapses in the developing hippocampus

Gustafsson, B.; Strandberg, J.

10.1101/2024.01.10.574846 — neuroscience — Posted on 2024-01-11

3197 Feedforward circuits enable modality-specific control of cortical inhibition during behavioral state transitions.

Rebola, N.; Zerlaut, Y.; De Brito Van Velze, M.; Dhanasobhon, D.; Martinez, M.; Morabito, A.; Martins Pinho, C.; Berthaux, E.

10.1101/2024.01.10.574973 — neuroscience — Posted on 2024-01-11

3198 Gating of Memory to Behavior by the Locus Coeruleus

Wang, T.; Duan, H.; Zhang, X.; Xia, D.; Li, T.; Yan, R.; Zhan, Y.; Li, Y.; Gao, W.-J.; Zhou, Q.

10.1101/2024.01.09.574947 — neuroscience — Posted on 2024-01-11

3199 Sensory representations in primary visual cortex are not sufficient for subjective imagery

Cabbai, G.; Racey, C.; Simner, J.; Dance, C.; Ward, J.; Forster, S.

10.1101/2024.01.10.574972 — neuroscience — Posted on 2024-01-11

3200 TRPV4 is expressed by enteric glia and muscularis macrophages of the colon but does not play a prominent role in colonic motility

Rajasekhar, P.; Carbone, S. E.; Johnston, S. T.; Nowell, C. J.; Wiklendt, L.; Crampin, E. J.; She, Y.; DiCello, J. J.; Saito, A.; Sorensen, L.; Nguyen, T.; Lee, K. M.; Hamilton, J. A.; King, S. K.; Eriksson, E. M.; Spencer, N. J.; Gulbransen, B. D.; Veldhuis, N. A.; Poole, D. P.

10.1101/2024.01.09.574831 — physiology — Posted on 2024-01-11

3201 Numerical modeling of senile plaque development under conditions of limited diffusivity of amyloid-β monomers

Kuznetsov, A. V.

10.1101/2024.01.09.574935 — biophysics — Posted on 2024-01-11

3202 Carbohydrate-active enzyme annotation in microbiomes using dbCAN

Zheng, J.; Huang, L.; Yi, H.; Yan, Y.; Zhang, X.; Akresi, J.; Yin, Y.

10.1101/2024.01.10.575125 — bioinformatics — Posted on 2024-01-11

3203 Designer micro/nano-crumpled MXene multilayer coatings accelerate osteogenesis and regulate macrophage polarization

Asadi Tokmedash, M.; Min, J.

10.1101/2024.01.10.574996 — bioengineering — Posted on 2024-01-11

3204 Plant Cell Wall Enzymatic Deconstruction: Bridging the Gap Between Micro and Nano Scales

Refahi, Y.; Zoghlami, A.; Vine, T.; Terryn, C.; Paes, G.

10.1101/2024.01.11.575220 — biochemistry — Posted on 2024-01-11

3205 Flap endonuclease Substrate Interactions studied using Dynamic Single-Molecule Atomic Force Microscopy

Verma, V.; Brudenell, E. L.; Cussons, S.; Phipps, J.; Kong, S. C.; Sayers, J. R.; Hobbs, J. K.

10.1101/2024.01.10.574983 — biochemistry — Posted on 2024-01-11

3206 An almost chromosome-level assembly and annotation of the Alectoris rufa genome

Eleiwa, A.; Nadal, J.; Vilaprinyo, E.; Marin-Sanguino, A.; Sorribas, A.; Basallo, O.; Lucido, A.; Richart, C.; Pena, R. N.; Ros-Freixedes, R.; Usie, A.; Alves, R.

10.1101/2024.01.11.575009 — genomics — Posted on 2024-01-11

3207 Pangenome reconstruction in rats enhances genotype-phenotype mapping and novel variant discovery

Villani, F.; Guarracino, A.; Ward, R. R.; Green, T.; Emms, M.; Pravenec, M.; Prins, P.; Garrison, E.; Williams, R. W.; Chen, H.; Colonna, V.

10.1101/2024.01.10.575041 — genomics — Posted on 2024-01-11

3208 Temporal and Functional Relationship between Synaptonemal Complex Morphogenesis and Recombination during Meiosis

Ahuja, J. S.; Sandhu, R.; Huang, L.; Klein, F.; Boerner, G. V.

10.1101/2024.01.11.575218 — genetics — Posted on 2024-01-11

3209 Convergent reductive evolution of cyanobacteria in symbiosis with Dinophysiales dinoflagellates

Nakayama, T.; Nomura, M.; Yabuki, A.; Shiba, K.; Inaba, K.; Inagaki, Y.

10.1101/2024.01.11.574452 — evolutionary biology — Posted on 2024-01-11

3210 Evidence for compensatory evolution within pleiotropic regulatory elements

Kliesmete, Z.; Orchard, P.; Lee, V. Y. K.; Geuder, J.; Krauss, S. M.; Ohnuki, M.; Jocher, J.; Vieth, B.; Enard, W.; Hellmann, I.

10.1101/2024.01.10.575014 — evolutionary biology — Posted on 2024-01-11

3211 Climate and urbanization drive changes in the habitat suitability of Schistosoma mansoni competent snails in Brazil

Glidden, C. K.; Singleton, A. L.; Chamberlin, A.; Tuan, R.; Palasio, R. G. S.; Calderia, R.; Monteiro, A. M. V.; Lwiza, K. M.; Liu, P.; Silva, V.; Athni, T. S.; Sokolow, S. H.; Mordecai, E. A.; De Leo, G. A.

10.1101/2024.01.03.574120 — ecology — Posted on 2024-01-11

3212 The interplay of facilitation and competition drives the emergence of multistability in dryland plant communities

Pichon, B.; Gounand, I.; Donnet, S.; Kefi, S.

10.1101/2024.01.09.573035 — ecology — Posted on 2024-01-11

3213 Unlocking the therapeutic potential of the corneal endothelium: Intravital imaging reveals endogenous regenerative capabilities

Marshall, M.; Ramarapu, R.; Ohman, L.; Samasa, B.; Papp, T.; Parhiz, H.; Park, S.; Leonard, B. C.; Thomasy, S. M.; Rompolas, P.

10.1101/2022.12.15.520611 — developmental biology — Posted on 2024-01-11

3214 Transcriptomic analysis of pubertal and adult virgin mouse mammary epithelial and stromal cell populations

Heijmans, N.; Wiese, K. E.; Jonkers, J.; van Amerongen, R.

10.1101/2024.01.11.575148 — developmental biology — Posted on 2024-01-11

3215 Measuring and modeling the dynamics of mitotic error correction

Ha, G.; Dieterle, P.; Shen, H.; Amir, A.; Needleman, D. J.

10.1101/2024.01.10.574250 — cell biology — Posted on 2024-01-11

3216 Human neural rosettes secrete bioactive extracellular vesicles enriched in neuronal and glial cellular components

Herrera Lopez, M.; Bertone Arolfo, M.; Remedi, M.; Gastaldi, L.; Wilson, C.; Guendulain, G. G.; Ceschin, D.; Cardozo Gizzi, A.; Caceres, A.; Moyano, A. L.

10.1101/2024.01.10.574187 — cell biology — Posted on 2024-01-11

3217 Complete absence of GLUT1 does not impair human terminal erythroid differentiation

Martins Freire, C.; King, N. R.; Dzieciatkowska, M.; Stephenson, D.; Moura, P. L.; Dobbe, J. G. G.; Streekstra, G. J.; D'Alessandro, A.; Toye, A. M.; Satchwell, T. J.

10.1101/2024.01.10.574621 — cell biology — Posted on 2024-01-11

3218 WRNIP1 prevents transcription-associated genomic instability

Valenzisi, P.; Marabitti, V.; Pichierri, P.; Franchitto, A.

10.1101/2023.06.23.546223 — cell biology — Posted on 2024-01-11

3219 Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus

Rasetto, N. B.; Giacomini, D.; Berardino, A. A.; Vega Waichman, T.; Beckel, M. S.; Di Bella, D. J.; Brown, J.; Davies-Sala, M. G.; Gerhardinger, C.; Lie, D. C.; Arlotta, P.; Chernomoretz, A.; Schinder, A. F.

10.1101/2023.11.03.565477 — neuroscience — Posted on 2024-01-11

3220 PTEN inhibition promotes robust growth of bulbospinal respiratory axons and partial recovery of diaphragm function in a chronic model of cervical contusion spinal cord injury

Michel-Flutot, P.; Cheng, L.; Thomas, S. J.; Lisi, B.; Schwartz, H.; Lam, S.; Lyttle, M.; Jaffe, D. A.; Smith, G. M.; Li, S.; Wright, M. C.; Lepore, A. C.

10.1101/2024.01.10.575021 — neuroscience — Posted on 2024-01-11

3221 Predicting cued and oddball visual search performance from neural representational similarity

Yeh, L.-C.; Thorat, S.; Peelen, M. V.

10.1101/2023.06.15.545065 — neuroscience — Posted on 2024-01-11

3222 Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS)

Hassett, K.; Potu, S. S.; Sankaramoorthy, A.; Leka, K.; Kaneshamoorthy, S.; Huentelman, M. J.; Narayanan, V.; Rangasamy, S.

10.1101/2024.01.09.574075 — neuroscience — Posted on 2024-01-11

3223 The role of locus coeruleus neuroimmune signaling in the response to social stress in female rats

Smiley, C. E.; Pate, B. S.; Bouknight, S. J.; Harrington, E. N.; Jasnow, A. M.; Wood, S. K.

10.1101/2024.01.10.575076 — neuroscience — Posted on 2024-01-11

3224 The medial entorhinal cortex encodes multisensory spatial information

Nyugen, D.; Wang, G.; Gu, Y.

10.1101/2024.01.09.574924 — neuroscience — Posted on 2024-01-11

3225 The deep-sea ecosystem engineer Geodia barretti (Porifera, Demospongiae) maintains basic physiological functions under simulated future ocean pH and temperature conditions

Wurz, E.; Ulvatn, T.; Kooistra, T.; Strauss, F.; Rapp, H. T.; de Goeij, J. M.; Osinga, R.

10.1101/2024.01.11.575017 — physiology — Posted on 2024-01-11

3226 Cognitive and molecular characterization of the Ts66Yah murine model of Down syndrome: deepening on hippocampal changes associated with genotype and aging.

Lanzillotta, C.; Rataj-Baniowska, M.; Prestia, F.; Sette, C.; Nalesso, V.; Perluigi, M.; Barone, E.; Duchon, A.; Tramutola, A.; Herault, Y.; Di Domenico, F.

10.1101/2024.01.02.573811 — pathology — Posted on 2024-01-11

3227 Clinical application of tumour-in-normal contamination assessment from whole genome sequencing

Mitchell, J.; Milite, S.; Bartram, J.; Walker, S.; Volkova, N.; Yavorska, O.; Zarowiecki, M.; Chalker, J.; Thomas, R.; Vago, L.; Sosinsky, A.; Caravagna, G.

10.1101/2022.03.09.483623 — bioinformatics — Posted on 2024-01-11

3228 Multimodal interactions in Stomoxys navigation reveals synergy between olfaction and vision.

Getahun, M. N.; Baleba, S. B.; Ngiela, J.; Ahuya, P.; Masiga, D.

10.1101/2024.01.11.575173 — ecology — Posted on 2024-01-11

3229 Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Wensveen, M. R.; Dixit, A. A.; Colmenares, S. U.; Janssen, A.

10.1101/2023.12.01.569547 — molecular biology — Posted on 2024-01-11

3230 Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation.

Cook, P. C.; Brown, S. L.; Houlder, E. L.; Baker, S.; Svedberg, F. R.; Howell, G.; Bertuzzi, M.; Boon, L.; Konkel, J. E.; Allen, J. E.; MacDonald, A. S.

10.1101/2023.11.24.568263 — immunology — Posted on 2024-01-11

3231 Tracking subjects' strategies in behavioural choice experiments at trial resolution

Maggi, S.; Hock, R. M.; O'Neill, M.; Buckley, M. J.; Moran, P. M.; Bast, T.; Sami, M.; Humphries, M. D.

10.1101/2022.08.30.505807 — neuroscience — Posted on 2024-01-11

3232 SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain

Mali, S. S.; Silva, R.; Gong, Z.; Cronce, M.; Vo, U.; Vuong, C.; Moayedi, Y.; Cox, J. S.; Bautista, D. M.

10.1101/2024.01.10.575114 — neuroscience — Posted on 2024-01-11

3233 Degradation of Fatty Acid Export Protein1 by Rhomboid-Like Protease11 Contributes to Cold Tolerance in Arabidopsis

John, A.; Kraemer, M.; Lehmann, M.; Kunz, H.-H.; Aarabi, F.; Alseekh, S.; Fernie, A. R.; Sommer, F.; Schroda, M.; Zimmer, D.; Muehlhaus, T.; Peisker, H.; Gutbrod, K.; Doermann, P.; Neunzig, J.; Philippar, K.; Neuhaus, H. E.

10.1101/2023.10.26.564161 — plant biology — Posted on 2024-01-11

3234 Procognitive and neurotrophic benefits of α5-GABA-A receptor positive allosteric modulation in a beta-amyloid deposition model of Alzheimer's disease pathology

Bernardo, A. M.; Marcotte, M.; Wong, K.; Sharmin, D.; Pandey, K. P.; Cook, J. M.; Sibille, E.; Prevot, T. D.

10.1101/2022.09.30.510361 — pharmacology and toxicology — Posted on 2024-01-11

3235 HAF Prevents Hepatocyte Apoptosis and Hepatocellular Carcinoma through Transcriptional Regulation of the NF-κB pathway.

Acuna-Pilarte, K.; Reichert, E. C.; Green, Y. S.; Halberg, L. M.-T.; McFarland, S. A.; Mimche, P.; Golkowski, M.; Kamden, S. D.; Maguire, K. M.; Summers, S.; Maschek, J. A.; Reelitz, J. W.; Cox, J.; Evason, K. J.; Koh, M. Y.

10.1101/2024.01.09.574894 — cancer biology — Posted on 2024-01-11

3236 Mutations in yeast are deleterious on average regardless of the degree of adaptation to the testing environment

Bao, K.; Strayer, B. R.; Braker, N. P.; Chan, A. A.; Sharp, N.

10.1101/2024.01.09.574908 — evolutionary biology — Posted on 2024-01-11

3237 WITHDRAWN: Environmentally-informed functional characterization of a plastid diatom metabolic bridge of mitochondrial origin

Dorrell, R. G.; Zhang, Y.; Liang, Y.; Gueguen, N.; Nonoyama, T.; Croteau, D.; Penot, M.; Adiba, S.; Bailleul, B.; Gros, V.; Pierella Karlusich, J. J.; Zweig, N.; Fernie, A. R.; Jouhet, J.; Marechal, E.; Bowler, C.

10.1101/2024.01.09.574873 — evolutionary biology — Posted on 2024-01-11

3238 Arthropod community composition in urban landscapes is shaped by both environmental filtering and dispersal limitation

Roper-Edwards, S.; Hurlbert, A. H.

10.1101/2024.01.09.574897 — ecology — Posted on 2024-01-11

3239 Taking identity-by-descent analysis into the wild: Estimating realized relatedness in free-ranging macaques

Freudiger, A.; Jovanovic, V. M.; Huang, Y.; Snyder-Mackler, N.; Conrad, D. F.; Miller, B.; Montague, M. J.; Westphal, H.; Stadler, P. F.; Bley, S.; Horvath, J. E.; Brent, L. J. N.; Platt, M. L.; Ruiz-Lambides, A.; Tung, J.; Nowick, K.; Ringbauer, H.; Widdig, A.

10.1101/2024.01.09.574911 — ecology — Posted on 2024-01-11

3240 A temporal map of division, chromatin modification, and identity specification in the regenerating Arabidopsis root.

Rahni, R.; Guillotin, B.; Lee, L. R.; Birnbaum, K. D.

10.1101/2024.01.09.574680 — developmental biology — Posted on 2024-01-11

3241 Peptidyl-tRNA hydrolysis rate influences the efficiency of nonsense-mediated mRNA decay

Kolakada, D.; Fu, R.; Biziaev, N.; Shuvalov, A.; Lore, M.; Campbell, A. E.; Cortazar, M. A.; Sajek, M. P.; Hesselberth, J. R.; Mukherjee, N.; Alkaeva, E.; Jagannathan, S.

10.1101/2024.01.10.575080 — molecular biology — Posted on 2024-01-11

3242 The glucocorticoid response element near the sphingosine-1-phopshate receptor 3 gene mitigates inflammatory processes and maladaptive behavior in females and stressed males

Corbett, B. F.; Luz, S.; Arner, J.; Yan, J.; Bhatnagar, S.

10.1101/2024.01.09.574910 — neuroscience — Posted on 2024-01-11

3243 Topographic variation in neurotransmitter receptor densities explains differences in intracranial EEG spectra

Stoof, U.; Friston, K.; Tisdall, M.; Cooray, G.; Rosch, R.

10.1101/2024.01.09.574882 — neuroscience — Posted on 2024-01-11

3244 Integrity of arousal-regulating brain circuitry predicts human cognitive abilities

Podvalny, E.; Sanchez-Romero, R.; Cole, M. W.

10.1101/2024.01.09.574917 — neuroscience — Posted on 2024-01-11

3245 ER-detect: a pipeline for robust detection of early evoked responses in BIDS-iEEG electrical stimulation data

van den Boom, M. A.; Gregg, N. M.; Valencia, G. O.; Lundstrom, B. N.; Miller, K. J.; van Blooijs, D.; Huiskamp, G. J. M.; Leijten, F. S. S.; Worrell, G. A.; Hermes, D.

10.1101/2024.01.09.574915 — neuroscience — Posted on 2024-01-11

3246 MATES: A Deep Learning-Based Model for Locus-specific Quantification of Transposable Elements in Single Cell

Wang, R.; Zheng, Y.; Zhang, Z.; Zhu, X.; Wu, T. P.; Ding, J.

10.1101/2024.01.09.574909 — bioinformatics — Posted on 2024-01-11

3247 Maternal den site fidelity of polar bears in western Hudson Bay

Klappstein, N. J.; McGeachy, D.; Pilfold, N. W.; Lunn, N. J.; Derocher, A. E.

10.1101/2024.01.09.574879 — ecology — Posted on 2024-01-11

3248 Rim4 is a Meiotic Thermal Sensor and Drives Biogenesis of Stress Granules

Zhang, R.; Li, S.; Feng, W.; Qian, S.; Chellappa, A. J.; Wang, F.

10.1101/2024.01.09.574866 — cell biology — Posted on 2024-01-11

3249 Phenotypic characterization of cryptic species in the fungal pathogen Histoplasma

Sepulveda, V. E.; Rader, J.; Li, J.; Goldman, W. E.; Matute, D. R.

10.1101/2024.01.08.574719 — microbiology — Posted on 2024-01-11

3250 xTrimoPGLM: Unified 100B-Scale Pre-trained Transformer for Deciphering the Language of Protein

Chen, B.; Cheng, X.; Li, P.; Gengyang, L.-a.; Gong, J.; Li, S.; Bei, Z.; Tan, X.; Wang, B.; Zeng, X.; Liu, C.; Zeng, A.; Dong, Y.; Tang, J.; Song, L.

10.1101/2023.07.05.547496 — synthetic biology — Posted on 2024-01-11

3251 Environmentally-informed functional characterization of a plastid diatom metabolic bridge of mitochondrial origin

10.1101/2024.01.09.574873 — evolutionary biology — Posted on 2024-01-11

3252 Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency

Sutter, S. O.; Jetzer, S.; Lkharrazi, A.; Pedersen, S.; Schraner, E. M.; Vogt, B.; Büning, H.; Fraefel, C.

10.1101/2024.01.08.574727 — microbiology — Posted on 2024-01-11

3253 Single-cell RNA sequencing unveils the hidden powers of zebrafish kidney for generating both hematopoiesis and adaptive antiviral immunity

Hu, C.; Zhang, N.; Hong, Y.; Tie, R.; Fan, D.; Lin, A.; Chen, Y.; Xiang, L.-x.; Shao, J.-z.

10.1101/2023.10.06.561285 — immunology — Posted on 2024-01-11

3254 Hyperactivity of mTORC1 and mTORC2-dependent signaling mediate epilepsy downstream of somatic PTEN loss.

Cullen, E. R.; Safari, M.; Mittelstadt, I.; Weston, M. C.

10.1101/2023.08.18.553856 — neuroscience — Posted on 2024-01-11

3255 A Novel Lossless Encoding Algorithm for Data Compression - Genomics Data as an Exemplar

Al-okaily, A. A.; Tbakhi, A.

10.1101/2020.08.24.264366 — bioinformatics — Posted on 2024-01-11

3256 An inappropriate decline in ribosome levels drives a diverse set of neurodevelopmental disorders

Ni, C.; Yu, L.; Vona, B.; Park, D.; Wei, Y.; Schmitz, D.; Wei, Y.; Ding, Y.; Sakurai, M.; Ballard, E.; Liu, Y.; Kumar, A.; Xing, C.; Kim, H.-G.; Ekmekci, C.; Karimiani, E.; Imannezhad, S.; Eghbal, F.; Badv, R.; Schwaibold, E.; Dehghani, M.; Mehrjardi, M.; Metanat, Z.; Eslamiyeh, H.; Khouj, E.; Alhajj, S.; Chedrawi, A.; Alves, C.; Houlden, H.; Kruer, M.; Alkuraya, F.; Cenik, C.; Maroofian, R.; Wu, J.; Buszczak, M.

10.1101/2024.01.09.574708 — developmental biology — Posted on 2024-01-11

3257 Brain transcriptomics reveals features of the host response after dengue virus type I infection induced central nervous system injury in AGB6 mice

Yu, N.; Chen, S.-g.; Liu, Y.-m.; Wang, P.; Wang, L.-l.; Hu, N.-n.; He, Z.; Li, X.; Lu, H.-j.; Jin, N.-y.

10.1101/2024.01.10.574956 — immunology — Posted on 2024-01-11

3258 N-cadherin dynamically regulates pediatric glioma cell migration in complex environments

Kim, D.; Olson, J. M.; Cooper, J. A.

10.1101/2023.04.04.535599 — cancer biology — Posted on 2024-01-11

3259 RAPSYN-Mediated Neddylation of BCR-ABL Alternatively Determines the Fate of Philadelphia Chromosome-positive Leukemia

Zhao, m.; Dai, B.; Li, X.; Zhang, Y.; Qiao, C.; Qin, Y.; Li, Z.; Li, Q.; Wang, S.; Yang, Y.; Chen, Y.

10.1101/2023.05.24.542110 — cancer biology — Posted on 2024-01-11

3260 Multi-Response Phylogenetic Mixed Models: Concepts andApplication

Halliwell, B.; Yates, L. A.; Holland, B. R.

10.1101/2022.12.13.520338 — evolutionary biology — Posted on 2024-01-11

3261 Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control

Smirnova, A. M.; Hronova, V.; Mohammad, M. P.; Herrmannova, A.; Gunisova, S.; Petrackova, D.; Halada, P.; Coufal, S.; Swirski, M.; Rendelman, J.; Jendruchova, K.; Hatzoglou, M.; Beznoskova, P.; Vogel, C.; Valasek, L. S.

10.1101/2023.07.12.548609 — molecular biology — Posted on 2024-01-11

3262 NanoTrans: an integrated computational framework for comprehensive transcriptome analyses with Nanopore direct-RNA sequencing

Yang, L.; Zhang, X.; Wang, F.; Zhang, L.; Li, J.; Yue, J.-X.

10.1101/2022.11.29.518309 — bioinformatics — Posted on 2024-01-11

3263 Sperm production and allocation in response to risks of sperm competition in the black soldier fly Hermetia illucens

Manas, F.; Labrousse, C.; Bressac, C.

10.1101/2023.06.20.544772 — evolutionary biology — Posted on 2024-01-11

3264 When less is more - A fast TurboID KI approach for high sensitivity endogenous interactome mapping

Stockhammer, A.; Spalt, C.; Benz, L.; Harel, S.; Natalia, V.; Wiench, L.; Freund, C.; Kuropka, B.; Bottanelli, F.

10.1101/2021.11.19.469212 — cell biology — Posted on 2024-01-11

3265 Robust control of replication initiation in the absence of DnaA-ATP {leftrightharpoons} DnaA-ADP regulatory elements in Escherichia coli

Boesen, T.; Charbon, G.; Fu, H.; Jensen, C.; Sandler, M.; Li, D.; Jun, S.; Lobner-Olesen, A.

10.1101/2022.09.08.507175 — microbiology — Posted on 2024-01-11

3266 Acetylcholine release from basal forebrain promotes cortical synaptic plasticity via somatostatin interneurons

Zhao, X.; Zhang, Y. E.; Yang, L.; Yang, Y.

10.1101/2023.07.05.547662 — neuroscience — Posted on 2024-01-11

3267 NK cells shape the clonal evolution of B cell leukaemia by IFN-γ production

Buri, M. C.; Shoeb, M. R.; Bykov, A.; Repiscak, P.; Baik, H.; Dupanovic, A.; David, F. O.; Kovacic, B.; Hall-Glenn, F.; Urbanus, J.; Sippl, L.; Stofner, S.; Emminger, D.; Cosgrove, J.; Lehner, M.; Perie, L.; Shumacher, T. N.; Gotthardt, D.; Halbritter, F.; Putz, E. M.

10.1101/2023.11.16.567430 — cancer biology — Posted on 2024-01-11

3268 A chaperone and a heat-resistant obscure (Hero) protein mediates conformational extension and aggregation suppression of TDP-43

Lam, A. Y. W.; Tsuboyama, K.; Tadakuma, H.; Tomari, Y.

10.1101/2022.11.15.516569 — biophysics — Posted on 2024-01-11

3269 Flexiplex: A versatile demultiplexer and search tool for omics data

Cheng, O.; Ling, M. H.; Wang, C.; Wu, S.; Ritchie, M. E.; Goeke, J. M.; Amin, N.; Davidson, N. M.

10.1101/2023.08.21.554084 — bioinformatics — Posted on 2024-01-11

3270 The contribution of gene flow, selection, and genetic drift to five thousand years of human allele frequency change

Simon, A.; Coop, G.

10.1101/2023.07.11.548607 — evolutionary biology — Posted on 2024-01-11

3271 Dining in the daylight: Nocturnal rhinoceros beetles extend feeding periods on host trees with reduced sap exudation

Kanda, A.; Shibata, R.; Ueno, T.; Yamashita, N.; Kojima, W.

10.1101/2023.12.25.573284 — ecology — Posted on 2024-01-11

3272 Defining the contribution of microRNA-specific slicing Argonautes in animals

Pal, A.; Vasudevan, V.; Houle, F.; Lantin, M.; Maniates, K. A.; Quevillon Huberdeau, M.; Abbott, A.; Simard, M. J.

10.1101/2023.01.19.524781 — molecular biology — Posted on 2024-01-11

3273 Prophages regulate Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta

Natarajan, O.; Gibboney, S. L.; Young, M. N.; Lim, S. J.; Pluta, N.; Atkinson, C. G. F.; Leigh, B. A.; Liberti, A.; Kees, E. D.; Breitbart, M.; Gralnick, J. A.; Dishaw, L. J.

10.1101/2022.11.23.517592 — microbiology — Posted on 2024-01-11

3274 Neuregulin1 nuclear signaling influences adult hippocampal neurogenesis and regulates a schizophrenia susceptibility gene network within the mouse dentate gyrus.

Rajebhosale, P.; Jone, A.; Johnson, K. R.; Hofland, R.; Palarpalar, C.; Khan, S.; Role, L. W.; Talmage, D. A.

10.1101/2022.08.10.503469 — neuroscience — Posted on 2024-01-11

3275 Atenolol reduces cardiac-mediated mortality in a genetic mouse model of sudden unexpected death in epilepsy

Soh, M. S.; Kuanyshbek, A.; Mohamed Syazwan, E. S.; Lee, H. M.; McKenzie, C. E.; Phillips, A. M.; Hu, A.; Scheffer, I. E.; Semsarian, C.; Berkovic, S. F.; Reid, C. A.

10.1101/2023.12.10.570964 — neuroscience — Posted on 2024-01-11

3276 A hierarchical atlas of the human cerebellum for functional precision mapping

Nettekoven, C. R.; Zhi, D.; Shahshahani, L.; Luisa Pinho, A.; Saadon-Grosmann, N.; Buckner, R. L.; Diedrichsen, J.

10.1101/2023.09.14.557689 — neuroscience — Posted on 2024-01-11

3277 Effect of diffusivity of amyloid beta monomers on the formation of senile plaques

Kuznetsov, A. V.

10.1101/2023.07.31.551367 — biophysics — Posted on 2024-01-11

3278 Numerical and analytical simulation of the growth of amyloid-β plaques

Kuznetsov, A. V.

10.1101/2023.09.11.557187 — biophysics — Posted on 2024-01-11

3279 A One-Step Plasma Assisted Synthesis of Gold Nanoparticles and Simultaneous Linker-Free Conjugation with Nestin: An In Vitro Study of Cellular toxicity.

Aalikhani, K.; Sanavandi, M.; Shafiee, M.; Rabbani, H.; Fazli, G.; Sadeghi, N.; Shokri, B.

10.1101/2023.12.09.570950 — biophysics — Posted on 2024-01-11

3280 HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging

Day, J. H.; Maretich, P.; Della Santina, C. M.; Auld, A. L.; Schneider, K. K.; Shin, T.; Boyden, E. S.; Boyer, L. A.

10.1101/2023.02.07.527509 — bioengineering — Posted on 2024-01-11

3281 Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface

Driggers, C. M.; Kuo, Y.-Y.; Zhu, P.; ElSheikh, A.; Shyng, S.-L.

10.1101/2023.08.01.551546 — biochemistry — Posted on 2024-01-11

3282 A bibliometric analysis of neurobiological and behavioraldisturbances of cafeteria diet interventions

Lopez-Castro, A.

10.1101/2024.01.09.574927 — animal behavior and cognition — Posted on 2024-01-11

3283 β-carotene accelerates the resolution of atherosclerosis in mice

Pinos, I.; Coronel, J.; Albakri, A.; Blanco, A.; McQueen, P.; Molina, D.; Sim, J.; Fisher, E. A.; Amengual, J.

10.1101/2023.03.07.531563 — immunology — Posted on 2024-01-11

3284 Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease

Young, C.; Singh, M.; Jackson, K. J.; Field, M. A.; Peters, T. J.; Angioletti-Uberti, S.; Frenkel, D.; Ravishankar, S.; Gupta, M.; Wang, J. J.; Agapiou, D.; Faulks, M. L.; Al-Eryani, G.; Luciani, F.; Gordon, T. P.; Reed, J. H.; Danta, M.; Carr, A.; Kelleher, A. D.; Dore, G. J.; Matthews, G.; Brink, R.; Bull, R. A.; Suan, D.; Goodnow, C. C.

10.1101/2024.01.07.574561 — immunology — Posted on 2024-01-11

3285 Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy

Abreo, T. J.; Thompson, E. C.; Madabushi, A.; Soh, H.; Varghese, N.; Vanoye, C. G.; Springer, K.; Park, K. L.; Johnson, J.; Sims, S.; Ji, Z.; Chavez, A. G.; Jankovic, M. J.; Habte, B.; Zuberi, A. R.; Lutz, C. M.; Wang, Z.; Krishnan, V.; Dudler, L.; Einsele-Scholz, S.; Noebels, J. L.; George, A. L.; Maheshwari, A.; Tzingounis, A.; Cooper, E.

10.1101/2024.01.04.574177 — neuroscience — Posted on 2024-01-11

3286 Children exhibit a developmental advantage in the offline processing of a learned motor sequence

Van Roy, A.; Albouy, G.; Burns, R. D.; King, B. R.

10.1101/2023.09.07.556746 — neuroscience — Posted on 2024-01-11

3287 Sex differences in social synchronization of conditioned fear.

Ito, W.; Morozov, A.

10.1101/2022.10.10.511569 — neuroscience — Posted on 2024-01-11

3288 p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

Regnier, M.; Polizzi, A.; Fougeray, T.; Fougerat, A.; Perrier, P.; Anderson, K.; Lippi, Y.; Smati, S.; Lukowicz, C.; Lasserre, F.; Fouche, E.; Huillet, M.; Rives, C.; Tramunt, B.; Naylies, C.; Garcia, G.; Rousseau-Bacquie, E.; Bertrand-Michel, J.; Canlet, C.; Chevolleau-Mege, S.; Debrauwer, L.; Heymes, C.; Burcelin, R.; Levade, T.; Gourdy, P.; Wahli, W.; Blum, Y.; Gamet-Payrastre, L.; Ellero-Simatos, S.; Guillermet-Guibert, J.; Hawkins, P.; Stephens, L.; Montagner, A.; Loiseau, N.; Guillou, H.

10.1101/2024.01.09.574858 — cell biology — Posted on 2024-01-10

3289 scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome

10.1101/2024.01.10.574801 — genomics — Posted on 2024-01-10

3290 Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus J1074

Jönsson, M.; Sigrist, R.; Semenov Petrov, M.; Marcussen, N.; Gren, T.; Palsson, B. O.; Yang, L.; Özdemir, E.

10.1101/2024.01.09.574332 — genomics — Posted on 2024-01-10

3291 Feedback loop regulation between viperin and viral hemorrhagic septicemia virus through competing protein degradation pathways

Lu, X.; Yi, M.; Hu, Z.; Yang, T.; Zhang, W.; Marsh, N. G.; jia, K.

10.1101/2024.01.09.574905 — immunology — Posted on 2024-01-10

3292 Sequencing coverage analysis for combinatorialDNA-based storage systems

Preuss, I.; Galili, B.; Yakhini, Z.; anavy, l.

10.1101/2024.01.10.574966 — synthetic biology — Posted on 2024-01-10

3293 Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement.

Vilela-Alves, G.; Manuel, R. R.; Viegas, A.; Carpentier, P.; Biaso, F.; Guigliarelli, B.; Pereira, I. C.; Romao, M. J.; Mota, C.

10.1101/2024.01.10.571421 — biochemistry — Posted on 2024-01-10

3294 Clonal Parabacteroides from Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn's Disease Complications

Singh, V.; West, G.; Fiocchi, C.; Good, C. E.; Katz, J.; Jacobs, M. R.; Dichosa, A. E. K.; Flask, C.; Wesolowski, M.; McColl, C.; Grubb, B.; Ahmed, S.; Bank, N. C.; Thamma, K.; Bederman, I.; Erokwu, B.; Yang, X.; Sundrud, M. S.; Menghin, P.; Basson, A. R.; Ezeji, J.; Viswanath, S. E.; Veloo, A.; Sykes, D. B.; Cominelli, F.; Rodriguez-Palacios, A.

10.1101/2024.01.09.574896 — genomics — Posted on 2024-01-10

3295 Towards a phylogenomic classification of Magnoliidae

Helmstetter, A. J.; Ezedin, Z.; Lirio, E. J. d.; Oliveira, S. M. d.; Chatrou, L. W.; Erkens, R. H. J.; Larridon, I.; Leempoel, K.; Maurin, O.; Roy, S.; Zuntini, A. R.; Baker, W. J.; Couvreur, T. L. P.; Forest, F.; Sauquet, H.

10.1101/2024.01.09.574948 — evolutionary biology — Posted on 2024-01-10

3296 A CPC-shelterin-BTR axis regulates mitotic telomere deprotection

Romero-Zamora, D.; Rogers, S.; Low, R. R. J.; Robinson, A. B.; Page, S. G.; Lane, B. J. E.; Lamm, N.; Ishikawa, F.; Hayashi, M. T.; Cesare, A. J.

10.1101/2024.01.09.574754 — molecular biology — Posted on 2024-01-10

3297 Estrogen receptor-related receptor (Esrra) induces ribosomal protein Rplp1-mediated adaptive hepatic translation during prolonged starvation

Tripathi, M.; Gauthier, K.; Sandireddy, R.; Zhou, J.; Gupta, P.; Sakthivel, S.; Jiemin, N.; Arul, K.; Tikno, K.; Park, S.-H.; Wang, L.; Ho, L.; Giguere, V.; Ghosh, S.; McDonnell, D. P.; Yen, P. M.; Singh, B. K.

10.1101/2024.01.09.574937 — molecular biology — Posted on 2024-01-10

3298 Menopause-associated proteomic and lipidomic alterations in high-density lipoprotein: Perimenopause is characterized by smaller triacylglycerols-enriched particles.

Lehti, S.; Korhonen, T.-M.; Soliymani, R.; Ruhanen, H.; Lahteenmaki, E.; Palviainen, M.; Siljander, P.; Lalowski, M.; Kakela, R.; Lehti, M.; Laakkonen, E. K.

10.1101/2024.01.10.574516 — molecular biology — Posted on 2024-01-10

3299 Gallein and isoniazid act synergistically to attenuate Mycobacterium tuberculosis growth in human macrophages

Rijal, R.; Gomer, R. H.

10.1101/2024.01.10.574965 — microbiology — Posted on 2024-01-10

3300 Comparative genomic analysis of Planctomycetota potential towards complex polysaccharide degradation identifies phylogenetically distinct groups of biotechnologically relevant microbes

Klimek, D.; Herold, M.; Calusinska, M.

10.1101/2024.01.10.575047 — microbiology — Posted on 2024-01-10

3301 Highly-resolved within-species dynamics in the human facial skin microbiome

Baker, J.; Qu, E.; Mancuso, C.; Tripp, A. D.; Conwill, A.; Lieberman, T.

10.1101/2024.01.10.575018 — microbiology — Posted on 2024-01-10

3302 Heterotrophic prokaryotes internal carbon recycling compensates mismatches between phytoplankton production and heterotrophic prokaryotic consumption

Eigemann, F.; Tait, K.; Temperton, B.; Hellweger, F. L.

10.1101/2024.01.10.574976 — microbiology — Posted on 2024-01-10

3303 The RNA from Pseudomonas aeruginosa impairs neutrophil responses favoring bacterial survival

Pittaluga, J. R.; Birnberg-Weiss, F.; Serafino, A.; Castro, J.; Castillo, L. A.; Martire-Greco, D.; Barrionuevo, P.; Fernandez, G. C.; Landoni, V. I.

10.1101/2024.01.10.574964 — immunology — Posted on 2024-01-10

3304 mgikit: Demultiplexing toolkit for MGI fastq files

Al Bkhetan, Z.; Wang, S.

10.1101/2024.01.09.574938 — bioinformatics — Posted on 2024-01-10

3305 Blocker-SELEX: A Structure-guided Strategy for Developing Inhibitory Aptamers Disrupting Undruggable Transcription Factor Interactions

Wei, Y.; Tan, W.; Wu, Q.; Li, T.; Liu, X.; Zhang, S.; Hou, Y.; Zhang, Y.; Luo, G.; Zhu, X.; Tao, Y.; Fan, M.; Sha, C.; Lin, A.; Qin, J.; Chen, W.; Fu, T.

10.1101/2024.01.09.574928 — biochemistry — Posted on 2024-01-10

3306 Cell Cycle Regulation has Shaped Budding Yeast Replication Origin Structure and Function

Diffley, J.; Lim, C. T.; Miller, T. C.; Tan, K. W.; Talele, s.; Early, A.; East, P.; Sanchez, H.; Dekker, N. H.; Costa, A.

10.1101/2024.01.10.575016 — biochemistry — Posted on 2024-01-10

3307 Substrate Specificities of DDX1: A Human DEAD-box protein

Moore, A. F. T.; Berhie, Y.; Weislow, I. S.; Koculi, E.

10.1101/2024.01.09.573566 — biochemistry — Posted on 2024-01-10

3308 Late consolidation of rRNA structure during co-transcriptional assembly in E. coli by time-resolved DMS footprinting

Hao, Y.; Hulscher, R. M.; Zinshteyn, B.; Woodson, S.

10.1101/2024.01.10.574868 — biochemistry — Posted on 2024-01-10

3309 Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

Cosgrove, B. D.; Bounds, L. R.; Taylor, C. K.; Su, A. L.; Rizzo, A. J.; Barrera, A.; Crawford, G. E.; Hoffman, B. D.; Gersbach, C. A.

10.1101/2024.01.10.574997 — genomics — Posted on 2024-01-10

3310 Genome - nuclear lamina interactions are multivalent and cooperative

Dauban, L.; Eder, M.; de Haas, M.; Franceschini-Santos, V. H.; Yanez-Cuna, J. O.; van Schaik, T.; Leemans, C.; Rademaker, K.; Martinez-Ara, M.; Martinovic, M.; de Wit, E.; van Steensel, B.

10.1101/2024.01.10.574825 — molecular biology — Posted on 2024-01-10

3311 Variant-specific interactions at the plasma membrane: Heparan sulfate's impact on SARS-CoV-2 binding kinetics

Conca, D. V.; Bano, F.; von Wiren, J.; Scherrer, L.; Svirelis, J.; Thorsteinsson, K.; Dahlin, A.; Bally, M.

10.1101/2024.01.10.574981 — microbiology — Posted on 2024-01-10

3312 Sensitivity of dairy calf Salmonella enterica serotype Cerro isolates to infection-relevant stressors

Raabis, S. M.; Westerman, T. L.; Cruz, E.; Deblois, C. L.; Suen, G.; Elfenbein, J. R.

10.1101/2024.01.10.575057 — microbiology — Posted on 2024-01-10

3313 A toxic environment selects for specialist microbiome in poison frogs

Caty, S. N.; Alvarez-Buylla, A.; Vasek, C.; Tapia, E. E.; Martin, N. A.; McLaughlin, T.; Weber, P. K.; Mayali, X.; Coloma, L. A.; Morris, M. M.; O'Connell, L. A.

10.1101/2024.01.10.574901 — microbiology — Posted on 2024-01-10

3314 Comparative genomic analysis of Bradyrhizobium strains with natural variability in the efficiency of nitrogen fixation, competitiveness, and adaptation to stressful edaphoclimatic conditions

Klepa, M. S.; diCenzo, G. C.; Hungria, M.

10.1101/2024.01.10.574934 — microbiology — Posted on 2024-01-10

3315 Using gene complementation to identify a SulP-family bicarbonate transporter in an N2-fixing cyanobacterial endosymbiont of an open ocean diatom

Nieves-Morion, M.; Romero-Garcia, R.; Bardi, S.; Lopez-Maury, L.; Hagemann, M.; Flores, E.; Foster, R. A.

10.1101/2024.01.10.573558 — microbiology — Posted on 2024-01-10

3316 The antagonistic transcription factors, EspM and EspN, regulate the ESX-1 secretion system in M. marinum

Nicholson, K. R.; Cronin, R. M.; Prest, R. J.; Menon, A. R.; Yang, Y.; Jennisch, M. K.; Champion, M.; Tobin, D. M.; Champion, P. A.

10.1101/2024.01.09.574899 — microbiology — Posted on 2024-01-10

3317 Chlamydia trachomatis modulates the expression of JAK-STAT signaling components to attenuate the Type II interferon response of epithelial cells

Fontanilla, F. L.; Carabeo, R.; Brinkworth, A. J.

10.1101/2024.01.09.574898 — microbiology — Posted on 2024-01-10

3318 Stratifying macrophages based on their infectious burden identifies novel host targets for intervention during Crohns disease associated adherent-invasive Escherichia coli infection

Li, X.; Cole, J.; Vaughan, D.; Xiao, Y.; Walker, D.; Wall, D. M.

10.1101/2024.01.10.575028 — microbiology — Posted on 2024-01-10

3319 A new and widespread group of fish apicomplexan parasites

Bonacolta, A. M.; Krause, J.; Smit, N. J.; Sikkel, P.; del Campo, J.

10.1101/2024.01.10.575052 — microbiology — Posted on 2024-01-10

3320 Effective assessment of CD4+ T cell Immunodominance patterns: impact of antigen processing and HLA restriction

Alvaro-Benito, M.; Abualrous, E. T.; Lingel, H.; Meltendorf, S.; Holzapfel, J.; Sticht, J.; Kuropka, B.; Clementi, C.; Kuppler, F.; Brunner-Weinzierl, M. C.; Freund, C.

10.1101/2024.01.10.574975 — immunology — Posted on 2024-01-10

3321 Neuropsychiatric sequelae in an experimental model of post-COVID syndrome in mice

Pimenta, J. C.; Beltrami, V. A.; Oliveira, B. D. S.; Queiroz-Junior, C. M.; Barsalini, J.; Teixeira, D. C.; Souza-Costa, L. P.; Lima, A. L. D.; Machado, C. A.; Parreira, B. Z. S. G.; Santos, F. R. d. S.; Costa, P. A. C.; Lacerda, L. D. S. B.; Goncalves, M. R.; Chaves, I. d. M.; Couto, M. G. G.; Costa, V. R. d. M.; Nobrega, N. R. C.; Silva, B. L.; Fonseca, T.; Resende, F.; Wnuk, N. T.; Umezu, H. L.; Campolina-Silva, G.; Andrade, A. C.; Santana de Aguiar, R.; Costa, G. M. J.; Guimaraes, P. P.; Silva, G. S. F.; Vieira, L. B.; Pinho, V.; Teixeira, A. L.; Teixeira, M. M.; Miranda, A. S.; Costa, V.

10.1101/2024.01.10.575003 — neuroscience — Posted on 2024-01-10

3322 Enhanced feature matching in single-cell proteomics characterizes response to IFN-gamma and reveals co-existence of different cell states

Krull, K. K.; Ali, S. A.; Krijgsveld, J.

10.1101/2024.01.10.575010 — systems biology — Posted on 2024-01-10

3323 Epigenetic and genetic differentiation between Coregonus species pairs

Venney, C. J.; Merot, C.; Normandeau, E.; Rougeux, C.; Laporte, M.; Bernatchez, L.

10.1101/2022.11.18.517126 — evolutionary biology — Posted on 2024-01-10

3324 Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders

Yang, K.; Hasegawa, Y.; Bhattarai, J. P.; Hua, J.; Dower, M.; Etyemez, S.; Prasad, N.; Duvall, L. G.; Paez, A. K.; Smith, A.; Wang, Y.; Zhang, Y.-F.; Lane, A. P.; Ishizuka, K.; Kamath, V.; Ma, M.; Kamiya, A.; Sawa, A.

10.1101/2022.09.23.509224 — molecular biology — Posted on 2024-01-10

3325 Spatial summation of pain is associated with pain expectations: Results from a home-based paradigm

Nastaj, J.; Skalski, J.; Budzisz, A.; Szikszay, T. M.; Swoboda, S.; Kowalska, W.; Nowak, D.; Zbroja, E.; Kruszyna, N.; Jakubinska, M.; Grygny, D.; Polczyk, R.; Malecki, A.; Luedtke, K.; Adamczyk, W. M.

10.1101/2022.09.30.510274 — physiology — Posted on 2024-01-10

3326 scplainer: using linear models to understand mass spectrometry-based single-cell proteomics data

Vanderaa, C.; Gatto, L.

10.1101/2023.12.14.571792 — bioinformatics — Posted on 2024-01-10

3327 Contrast-enhanced photon-counting micro-CT of tumor xenograft models

Li, M.; Guo, X.; Verma, A.; Rudkouskaya, A.; McKenna, A.; Intes, X. R. M.; Wang, G.; Barroso, M.

10.1101/2024.01.03.574097 — bioengineering — Posted on 2024-01-10

3328 Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of Pseudomonas aeruginosa Virulence Phenotypes

Fihn, C.; Lembke, H.; Gaulin, J.; Bouchard, P.; Villarreal, A. R.; Penningroth, M. R.; Crone, K.; Vogt, G.; Gilbertsen, A.; Ayotte, Y.; CouthinodeOliveira, L.; Serrano-Wu, M.; Drouin, N.; Hung, D.; Hunter, R. C.; Carlson, E. E.

10.1101/2023.05.02.539119 — microbiology — Posted on 2024-01-10

3329 The Brain Image Library: A Community-Contributed Microscopy Resource for Neuroscientists

Kenney, M.; Vasylieva, I.; Hood, G.; Cao-Berg, I.; Tuite, L.; Laghaei, R.; Watson, A. M.; Ropelewski, A. J.

10.1101/2023.12.22.573024 — neuroscience — Posted on 2024-01-10

3330 Diabetes alters neuroeconomically dissociable forms of mental accounting

Nwakama, C.; Durand-de Cuttoli, R.; Oketokoun, Z. M.; Brown, S. O.; Haller, J. E.; Mendez, A.; Farshbaf, M. J.; Cho, Y. Z.; Ahmed, S.; Leng, S.; Ables, J. L.; Sweis, B. M.

10.1101/2024.01.04.574210 — neuroscience — Posted on 2024-01-10

3331 Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease

Sirkis, D. W.; Solsberg, C. W.; Johnson, T. P.; Bonham, L. W.; Oddi, A. P.; Geier, E. G.; Miller, B. L.; Rabinovici, G. D.; Yokoyama, J. S.

10.1101/2023.09.26.559634 — neuroscience — Posted on 2024-01-10

3332 Simulating growth of TDP-43 cytosolic inclusion bodies in neuron soma

Kuznetsov, A. V.

10.1101/2023.11.28.569118 — biophysics — Posted on 2024-01-10

3333 TDP-43 pathology links innate and adaptive immunity in amyotrophic lateral sclerosis

Evangelista, B. A.; Ragusa, J. V.; Pellegrino, K.; Wu, Y.; Quiroga-Barber, I.; Cahalan, S. R.; Arooji, O. K.; Madren, J. A.; Schroeter, S.; Cozzarin, J.; Xie, L.; Chen, X.; White, K. K.; Ezzell, J. A.; Iannone, M. A.; Cohen, S.; Traub, R. E.; Li, X.; Bedlack, R.; Phanstiel, D. H.; Meeker, R.; Stanley, N.; Cohen, T. J.

10.1101/2024.01.07.574541 — cell biology — Posted on 2024-01-10

3334 Methylotrophic methanogenesis in the Archaeoglobi revealed by cultivation of Ca. Methanoglobus hypatiae from a Yellowstone hot spring

Lynes, M. M.; Jay, Z. J.; Kohtz, A. J.; Hatzenpichler, R.

10.1101/2023.09.08.556235 — microbiology — Posted on 2024-01-10

3335 Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes

Chowdhury, J. M.; Chacin Ruiz, E. A.; Swindle-Reilly, K. E.; Ford Versypt, A. N.

10.1101/2023.05.05.539491 — systems biology — Posted on 2024-01-10

3336 Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury

Varadharajan, V.; Ramachandiran, I.; Massey, W. J.; Jain, R.; Banerjee, R.; Horak, A. J.; McMullen, M. R.; Huang, E.; Bellar, A.; Lorkowski, S. W.; Gulshan, K.; Helsley, R. N.; James, I.; Pathak, V.; Dasarathy, J.; Welch, N.; Dasarathy, S.; Streem, D.; Reizes, O.; Allende, D. S.; Smith, J. D.; Simcox, J.; Nagy, L. E.; Brown, J. M.

10.1101/2023.09.26.559533 — pathology — Posted on 2024-01-10

3337 Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice

Lyon, G.; Longo, J.; Garcia, A.; Inusa, F.; Marchi, E.; Shi, D.; Doerfel, M.; Arnesen, T.; Aldabe, R.; Lyons, S. K.; Nashat, M.; Bolton, D.

10.1101/2023.04.27.538618 — genetics — Posted on 2024-01-10

3338 The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 substrates in Mycobacterium marinum

Jones, B. S.; Hu, D. D.; Nicholson, K. R.; Cronin, R. M.; Champion, M.; Champion, P. A.

10.1101/2024.01.09.574891 — microbiology — Posted on 2024-01-10

3339 Associations between common genetic variants and income provide insights about the socioeconomic health gradient

Kweon, H.; Burik, C. A. P.; Ning, Y.; Ahlskog, R.; Xia, C.; Abner, E.; Bao, Y.; Bhatta, L.; Faquih, T.; Feijter, M.; Fisher, P.; Gelemanovic, A.; Giannelis, A.; Hottenga, J.-J.; Khalili, B.; Lee, Y.; Li-Gao, R.; Masso, J.; Myhre, R.; Palviainen, T.; Rietveld, C. A. P.; Teumer, A.; Verweij, R. M.; Willoughby, E. A.; Agerbo, E.; Bergmann, S.; Boomsma, D. I.; Borglum, A. D.; Brumpton, B. M.; Davies, N. M.; Esko, T.; Gordon, S. D.; Homuth, G.; Ikram, A.; Johannesson, M.; Kaprio, J.; Kidd, M. P.; Kutalik, Z.; Kwong, A. S. F.; Lee, J.; Luik, A.; Mook-Kanamori, D. O.; Magnus, P.; Marques-Vidal, P.; M

10.1101/2024.01.09.574865 — genetics — Posted on 2024-01-10

3340 A Genetic Screen for regulators of CNS morphology in Drosophila

Lacin, H.; Zhu, Y.; DiPaola, J.; Wilson, B. A.; Zhu, Y.; Skeath, J. B.

10.1101/2024.01.09.574922 — genetics — Posted on 2024-01-10

3341 Tracing back the expansion of the endomembrane rescue systems in parasitic Parabasalids to the ancestral origin in its free-living sister lineage

Shinde, A. P.; Kucerova, J.; Dacks, J. B.; Tachezy, J.

10.1101/2024.01.09.574884 — evolutionary biology — Posted on 2024-01-10

3342 Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification

Zhang, C.; Wu, B.; Wu, Y. F.; di Ciano-Oliviera, C.; Soria-Bretones, I.; Pham, N.-A.; Elia, A. J.; Chari, R.; Lam, W. L.; Bray, M. R.; Mak, T. W.; Tsao, M.-S.; Cescon, D. W.; Thu, K. L.

10.1101/2024.01.09.574105 — cancer biology — Posted on 2024-01-10

3343 Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

Howard, G. C.; Wang, J.; Rose, K. L.; Jones, C.; Patel, P.; Tsui, T.; Florian, A. C.; Vlach, L.; Lorey, S. L.; Grieb, B. C.; Smith, B. N.; Slota, M. J.; Reynolds, E. M.; Goswami, S.; Savona, M. R.; Mason, F. M.; Lee, T.; Fesik, S. W.; Liu, Q.; Tansey, W. P.

10.1101/2023.07.26.550648 — cancer biology — Posted on 2024-01-10

3344 Growth-induced collective bending and kinetic trapping of cytoskeletal filaments

Banerjee, D. S.; Freedman, S. L.; Murrell, M. P.; Banerjee, S.

10.1101/2024.01.09.574885 — biophysics — Posted on 2024-01-10

3345 Transient frequency preference responses in cell signaling systems

Szischik, C. L.; Szemere, J. R.; Balderrama, R.; Sanchez de la Vega, C.; Ventura, A. C.

10.1101/2024.01.09.574874 — biophysics — Posted on 2024-01-10

3346 Measuring concentration of nanoparticles in polydisperse mixtures using interferometric nanoparticle tracking analysis (iNTA)

Kashkanova, A. D.; Albrecht, D.; Kueppers, M.; Blessing, M.; Sandoghdar, V.

10.1101/2024.01.09.574819 — biophysics — Posted on 2024-01-10

3347 Energy allocation theory for bacterial growth control in and out of steady state

Cylke, A.; Serbanescu, D.; Banerjee, S.

10.1101/2024.01.09.574890 — biophysics — Posted on 2024-01-10

3348 Kernel-smoothed permutation for extreme P-value estimation in genetic association studies

Bian, J.; Li, C.; Wu, J.; Long, Q.

10.1101/2024.01.09.574752 — bioinformatics — Posted on 2024-01-10

3349 The Scalable Variant Call Representation: Enabling Genetic Analysis Beyond One Million Genomes

Poterba, T.; Vittal, C.; King, D.; Goldstein, D.; Goldstein, J.; Schultz, P.; Karczewski, K.; Seed, C.; Neale, B.

10.1101/2024.01.09.574205 — bioinformatics — Posted on 2024-01-10

3350 Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells

Grenell, A. B.; Singh, C.; Raju, M.; Wolk, A.; Dalvi, S.; Jang, G.-F.; Crabb, J. S.; Hershberger, C. E.; Manian, K. V.; Crabb, J. W.; Singh, R.; Du, J.; Anand-Apte, B.

10.1101/2024.01.05.574411 — biochemistry — Posted on 2024-01-10

3351 Migratory herbivorous waterfowl track multiple resource waves during spring migration

Xu, F.; Wu, W.; Wei, J.; Xin, Q.; Wielstra, B.; La Sorte, F. A.; Ma, Z.; Lei, G.; Lei, J.; Wu, W.; Yang, Y.; Gong, P.; Xu, B.; Si, Y.

10.1101/2023.04.14.536842 — ecology — Posted on 2024-01-10

3352 Step selection analysis with non-linear and random effects in mgcv

Klappstein, N. J.; Michelot, T.; Fieberg, J.; Pedersen, E. J.; Field, C.; Mills Flemming, J.

10.1101/2024.01.05.574363 — ecology — Posted on 2024-01-10

3353 A new role for IFRD1 in regulation of ER stress in bladder epithelial homeostasis

Fashemi, B. E.; Rougeau, A. K.; Salazar, A. M.; Bark, S. J.; Chappidi, R.; Brown, J. W.; Cho, C. J.; Mills, J. C.; Mysorekar, I. U.

10.1101/2024.01.09.574887 — cell biology — Posted on 2024-01-10

3354 EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in Pseudomonas aeruginosa

Patrauchan, M. A.; Burch-Konda, J.; Hull, M.; Achour, M.; Kayastha, B.; Kubo, A.; Braga, R.; Winton, L.; Rogers, R.; McCoy, J.; Lutter, E. I.

10.1101/2024.01.09.574892 — microbiology — Posted on 2024-01-10

3355 Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling

Yuk, C. M.; Kim, D.; Hong, S.; Kim, M.; Jeong, H.-W.; Park, S. J.; Min, H.; Kim, W.; Kim, S.-G.; Seong, R. H.; Kim, S.; Lee, S.-H.

10.1101/2024.01.08.574595 — immunology — Posted on 2024-01-10

3356 A split-GAL4 driver line resource for Drosophila CNS cell types

Meissner, G. W.; Vannan, A.; Jeter, J.; Atkins, M.; Bowers, S.; Close, K.; DePasquale, G. M.; Dorman, Z.; Forster, K.; Beringer, J. A.; Gibney, T. V.; Gulati, A.; Hausenfluck, J. H.; He, Y.; Henderson, K.; Johnson, L.; Johnston, R. M.; Ihrke, G.; Iyer, N.; Lazarus, R.; Lee, K.; Li, H.-H.; Liaw, H.-P.; Melton, B.; Miller, S.; Motaher, R.; Novak, A.; Ogundeyi, O.; Petruncio, A.; Price, J.; Protopapas, S.; Tae, S.; Tata, A.; Taylor, J.; Vorimo, R.; Yarbrough, B.; Zeng, K. X.; Zugates, C. T.; Dionne, H.; Angstadt, C.; Ashley, K.; Cavallaro, A.; Dang, T.; Gonzalez, G. A.; Hibbard, K. L.; Huang, C.;

10.1101/2024.01.09.574419 — neuroscience — Posted on 2024-01-10

3357 Control of neuronal excitation-inhibition balance by BMP-SMAD1 signaling

Okur, Z.; Schlauri, N.; Bitsikas, V.; Panopoulou, M.; Ortiz, R.; Schwaiger, M.; Karmakar, K.; Schreiner, D.; Scheiffele, P.

10.1101/2023.03.11.532164 — neuroscience — Posted on 2024-01-10

3358 Extreme miniaturization in plasmid design: generation of the 903 bp cloning vector pICOt2

Staal, J.; Beyaert, R.

10.1101/2023.11.29.569326 — synthetic biology — Posted on 2024-01-10

3359 Mind the instructions: reward cues are liked first, wanted later

Prutean, N.; Vermeylen, L.; Kukkonen, N.; Steendam, T. S.; Eayrs, J. O.; Krebs, R. M.; Wiersema, J. R.; Vassena, E.; Boehler, N. C.; Notebaert, W.

10.1101/2024.01.09.574803 — animal behavior and cognition — Posted on 2024-01-10

3360 Comparative analysis of the plasma metabolome of migrating passerines during stopover: Novel insights into flight metabolism

Domer, A.; Jasinska, W.; Rosental, L.; Shochat, E.; Fernie, A. R.; Alseekh, S.; Brotman, Y.; Ovadia, O.

10.1101/2024.01.09.574878 — ecology — Posted on 2024-01-10

3361 Anatomical and functional organization of cardiac fibers in the porcine cervical vagus nerve allows spatially selective efferent neuromodulation

Thompson, N.; Ravagli, E.; Mastitskaya, S.; Challita, R.; Hadaya, J.; Iacoviello, F.; Shah Idil, A.; Shearing, P. R.; Ajijola, O. A.; Ardell, J. L.; Shivkumar, K.; Holder, D.; Aristovich, K.

10.1101/2024.01.09.574861 — neuroscience — Posted on 2024-01-10

3362 Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment

10.1101/2024.01.09.574815 — neuroscience — Posted on 2024-01-10

3363 Traveling waves shape neural population dynamics enabling predictions and internal model updating

Mohanta, S.; Cleveland, D. M.; Afrasiabi, M.; Rhone, A. E.; Gorska, U.; Cooper Borkenhagen, M.; Sanders, R. D.; Boly, M.; Nourski, K. V.; Saalmann, Y. B.

10.1101/2024.01.09.574848 — neuroscience — Posted on 2024-01-10

3364 Reduced intra-tendinous sliding in Achilles tendinopathy during active plantarflexion regardless of horizontal foot position

Lecompte, L.; Crouzier, M.; Bogaerts, S.; Scheys, L.; Vanwanseele, B.

10.1101/2024.01.09.574669 — pathology — Posted on 2024-01-10

3365 Computationally guided exploration of borosin biosynthetic strategies

Lee, A. R.; Carter, R. S.; Imani, A. S.; Dommaraju, S. R.; Hudson, G. A.; Mitchell, D. A.; Freeman, M. F.

10.1101/2024.01.09.574750 — bioinformatics — Posted on 2024-01-10

3366 Production of biologically active human basic Fibroblast Growth Factor (hFGFb) using Nicotiana tabacum transplastomic plants

Müller, C.; Budnik, N.; Mirkin, F. G.; Vater, C. F.; Bravo-Almonacid, F. F.; Perez-Castro, C.; Wirth, S. A.; Segretin, M. E.

10.1101/2024.01.09.574869 — bioengineering — Posted on 2024-01-10

3367 Song Torrent: A modular, open-source 96-chamber audio and video recording apparatus with optogenetic activation and inactivation capabilities for Drosophila

Sawtelle, S.; Narayan, L.; Ding, Y.; Kim, E.; Berhman, E. L.; Lillvis, J. L.; Kawase, T.; Stern, D. L.

10.1101/2024.01.09.574712 — animal behavior and cognition — Posted on 2024-01-10

3368 Exploratory and risk-taking behaviours in coexisting rodents

Hughes, B.; Bowman, J.; Schulte-Hostedde, A.

10.1101/2024.01.09.574853 — ecology — Posted on 2024-01-10

3369 Generation and evaluation of protease inhibitor-resistant SARS-CoV-2 strains

Bouzidi, H. S.; Driouich, J.-S.; Klitting, R.; Bernadin, O.; Piorkowski, G.; Amaral, R.; Fraisse, L.; Mowbray, C. E.; Scandale, I.; Escudie, F.; Chatelain, E.; de Lamballerie, X.; Nougairede, A.; Touret, F.

10.1101/2023.11.22.568013 — microbiology — Posted on 2024-01-10

3370 The rapid decline in interaural-time-difference sensitivity for pure tones can be explained by peripheral filtering

Goupell, M. J.; Stecker, G. C.; Williams, B. T.; Bilokon, A.; Tollin, D. J.

10.1101/2023.08.04.551950 — neuroscience — Posted on 2024-01-10

3371 Machine learning of brain-specific biomarkers from EEG

Bomatter, P.; Paillard, J.; Garces, P.; Hipp, J. F.; Engemann, D. A.

10.1101/2023.12.15.571864 — neuroscience — Posted on 2024-01-10

3372 Acetylcholine release from basal forebrain promotes cortical synaptic plasticity via somatostatin interneurons

Zhao, X.; Zhang, Y. E.; Yang, L.; Yang, Y.

10.1101/2023.07.05.547662 — neuroscience — Posted on 2024-01-10

3373 Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers

Heindorf, M.; Keller, G. B.

10.1101/2022.01.31.478462 — neuroscience — Posted on 2024-01-10

3374 A stochastic world model on gravity for stability inference

Huang, T.; Liu, J.

10.1101/2022.12.30.522364 — neuroscience — Posted on 2024-01-10

3375 Control of intestinal stemness and cell lineage by histone variant H2A.Z isoforms

Rispal, J.; Rives, C.; Jouffret, V.; Leoni, C.; Dubois, L.; Chevillard-Briet, M.; Trouche, D.; Escaffit, F.

10.1101/2023.10.10.561706 — physiology — Posted on 2024-01-10

3376 Intermittent fasting promotes ILC3s secreting IL-22 contributing to the beigeing of white adipose tissue

Chen, H.; Sun, L.; Feng, L.; Han, X.; Zhang, Y.; Zhai, W.; Zhang, Z.; Mulholland, M.; Zhang, W.; Yin, Y.

10.1101/2023.08.29.555436 — physiology — Posted on 2024-01-10

3377 Scots pine - panmixia and the elusive signal of genetic adaptation

Bruxaux, J.; Zhao, W.; Hall, D.; Curtu, A. L.; Androsiuk, P.; Drouzas, A. D.; Gailing, O.; Konrad, H.; Sullivan, A. R.; Semerikov, V.; Wang, X.-R.

10.1101/2023.06.09.543371 — evolutionary biology — Posted on 2024-01-10

3378 Genome biology and evolution of mating type loci in four cereal rust fungi

Luo, Z.; McTaggart, A. R.; Schwessinger, B.

10.1101/2023.03.02.530769 — evolutionary biology — Posted on 2024-01-10

3379 Threshold-Free Network-Oriented Statistics in Neuroscience

Hao, Z.; Wang, P.; Xia, X.; Pan, Y.; Dou, W.

10.1101/2024.01.03.574016 — neuroscience — Posted on 2024-01-10

3380 Noncanonical Activity of Med4 as a Gatekeeper of Metastasis through Epigenetic Control of Integrin Signaling

Bae, S.-Y.; Chen, Y.; Chen, H.; Kumar, D.; Karaiskos, S.; Xu, J. J.; Lu, C.; Viny, A. D.; Giancotti, F. G.

10.1101/2023.11.18.566087 — cancer biology — Posted on 2024-01-10

3381 Devising reliable and accurate epigenetic clocks:choosing the optimal computational solution

Vavourakis, C. D.; Herzog, C. M.; Widschwendter, M.

10.1101/2023.10.13.562187 — genomics — Posted on 2024-01-10

3382 Assessing the dynamics of Mycobacterium bovis infection in three French badger populations

Calenge, C.; Payne, A.; Reveillaud, E.; Richomme, C.; Girard, S.; Desvaux, S.

10.1101/2023.05.31.543041 — ecology — Posted on 2024-01-10

3383 mGlu2 and mGlu3 receptor negative allosteric modulators attenuate the interoceptive effects of alcohol in male and female rats

Tyler, R. E.; Van Voorhies, K.; Blough, B. E.; Landavazo, A.; Besheer, J.

10.1101/2022.04.16.488559 — neuroscience — Posted on 2024-01-10

3384 Hydrothermal vent fauna of the Galapagos Rift: Updated species list with new records

Chen, C.; Jamieson, J. W.; Tunnicliffe, V.

10.1101/2023.11.28.568903 — zoology — Posted on 2024-01-10

3385 Sex chromosome turnover in hybridizing stickleback lineages

Yi, X.; Wang, D.; Reid, K.; Feng, X.; Löytynoja, A.; Merilä, J.

10.1101/2023.11.06.565909 — evolutionary biology — Posted on 2024-01-09

3386 Tertiary-interaction characters enable fast, model-based structural phylogenetics beyond the twilight zone

Puente-Lelievre, C.; Malik, A. J.; Douglas, J.; Ascher, D.; Baker, M.; Allison, J.; Poole, A. M.; Lundin, D.; Fullmer, M.; Bouckaert, R.; Kim, H.; Steinegger, M.; Matzke, N. J.

10.1101/2023.12.12.571181 — evolutionary biology — Posted on 2024-01-09

3387 Use of Large Language Models to Aid Analysis of Textual Data

Tai, R. H.; Bentley, L. R.; Xia, X.; Sitt, J. M.; Fankhauser, S. C.; Chicas-Mosier, A. M.; Monteith, B. G.

10.1101/2023.07.17.549361 — scientific communication and education — Posted on 2024-01-09

3388 ASY3 has dosage-dependent diverse effects on meiotic crossover formation

Chu, L.; Zhuang, J.; Geng, M.; Zhang, Y.; Zhang, C.; Schnittger, A.; Yi, B.; Yang, C.

10.1101/2024.01.09.574930 — plant biology — Posted on 2024-01-09

3389 Twilight length alters growth, flowering time, and clock function in Arabidopsis via LHY/CCA1

Mehta, D.; Scandola, S.; Kennedy, C.; Lummer, C.; Rodriguez Gallo, M. C.; Grubb, L. E.; Tan, M.; Scarpella, E.; Uhrig, R. G.

10.1101/2023.06.09.544111 — plant biology — Posted on 2024-01-09

3390 Designing Bt constructs for Brassicas, with minimal IP issues: A case study

Hassan, M. M.; Tenazas, F.; Williams, A.; Chiu, J.-w.; Robin, C.; Russell, D.; Golz, J. F.

10.1101/2024.01.09.574921 — plant biology — Posted on 2024-01-09

3391 Target-aware Molecule Generation for Drug Design Using a Chemical Language Model

Xia, Y.; Wu, K.; Deng, P.; Liu, R.; Zhang, Y.; Guo, H.; Cui, Y.; Pei, Q.; Wu, L.; Xie, S.; Chen, S.; Lu, X.; Hu, S.; Wu, J.; Chan, C.-K.; Chen, S.; Zhou, L.; Yu, N.; Liu, H.; Guo, J.; Qin, T.; Liu, T.-Y.

10.1101/2024.01.08.574635 — biochemistry — Posted on 2024-01-09

3392 Origin and adult renewal of the gut lacteal musculature from villus myofibroblasts

Sanketi, B. D.; Mantri, M.; Huang, L.; Tavallaei, M. A.; Hu, S.; Wang, M. F. Z.; De Valminck, I.; Kurpios, N. A.

10.1101/2023.01.19.523242 — developmental biology — Posted on 2024-01-09

3393 Development of Pial Collaterals by Extension of Pre-existing Artery Tips

Kumar, S.; Shanavas, N.; Ghosh, S.; Sivaramakrishnan, V.; Dwari, M.; Das, S.

10.1101/2023.12.07.570539 — developmental biology — Posted on 2024-01-09

3394 Differences in Alu vs L1-rich chromosome bands underpin architectural reorganization of the inactive-X chromosome and SAHFs

Lawrence, J. B.; Hall, L. L.; Creamer, K. M.; Byron, M. F.

10.1101/2024.01.09.574742 — cell biology — Posted on 2024-01-09

3395 Fungal-bacteria interactions provide shelter for bacteria in Caesarean section scar diverticulum

Chen, P.; Chen, H.; Liu, Z.; Pan, X.; Liu, Q.; Yang, X.

10.1101/2023.08.07.552220 — microbiology — Posted on 2024-01-09

3396 NAD+ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages

Iske, J.; El Fatimy, R.; Nian, Y.; Ghouzlani, A.; Eskandari, S.; Cetina Biefer, H. R.; Vasudevan, A.; Elkhal, A.

10.1101/2020.03.29.013649 — immunology — Posted on 2024-01-09

3397 Distinct effects of phyllosphere and rhizosphere microbes on invader Ageratina adenophora during its early life stages

Zeng, Z.-y.; Huang, J.-R.; Liu, Z.-Q.; Yang, A.-L.; Li, Y.-X.; Wang, Y.-L.; Zhang, H.-B.

10.1101/2024.01.09.574925 — plant biology — Posted on 2024-01-09

3398 Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

Do, B. T.; Hsu, P. P.; Vermeulen, S. Y.; Wang, Z.; Hirz, T.; Abbott, K. L.; Aziz, N.; Replogle, J. M.; Bjelosevic, S.; Paolino, J.; Nelson, S.; Block, S.; Darnell, A. M.; Ferreira, R.; Zhang, H.; Milosevic, J.; Schmidt, D. R.; Chidley, C.; Harris, I. S.; Weissman, J. S.; Pikman, Y.; Stegmaier, K.; Cheloufi, S.; Su, X. A.; Sykes, D. B.; Vander Heiden, M. G.

10.1101/2022.08.16.503984 — cancer biology — Posted on 2024-01-09

3399 Characterization of Recombinant Human Lactoferrin Expressed in Komagataella Phaffii

Lu, X.; Cummings, C.; Osuala, U. A.; Yennawar, N. H.; Namitz, K. E. W.; Hellner, B.; Besada-Lombana, P. B.; Peterson, R. D.; Clark, A. J.

10.1101/2024.01.09.574900 — biophysics — Posted on 2024-01-09

3400 ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism

Rashan, E. H.; Bartlett, A. K.; Khana, D. B.; Zhang, J.; Jain, R.; Smith, A. J.; Baker, Z. N.; Cook, T.; Caldwell, A.; Chevalier, A. R.; Pfleger, B. F.; Yuan, P.; Amador-Noguez, D.; Simcox, J. A.; Pagliarini, D. J.

10.1101/2024.01.09.574893 — biochemistry — Posted on 2024-01-09

3401 Substrate recognition mechanism of the endoplasmic reticulum-associated ubiquitin ligase Doa10

Wu, K.; Itskanov, S.; Lynch, D. L.; Chen, Y.; Turner, A.; Gumbart, J.; Park, E.

10.1101/2024.01.09.574907 — biochemistry — Posted on 2024-01-09

3402 Transposon fusion gave birth to Fem, Bombyx mori female determining gene

Lee, J.; Fujimoto, T.; Yamaguchi, K.; Shigenobu, S.; Sahara, K.; Toyoda, A.; Shimada, T.

10.1101/2024.01.09.574859 — genetics — Posted on 2024-01-09

3403 Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation

Singh, P. N. P.; Gu, W.; Madha, S.; Lynch, A. W.; Cejas, P.; He, R.; Bhattacharya, S.; Gomez, M. M.; Oser, M. G.; Brown, M.; Long, H. W.; Meyer, C. A.; Zhou, Q.; Shivdasani, R.

10.1101/2024.01.09.574746 — molecular biology — Posted on 2024-01-09

3404 Experimental variables that impact outcomes in Caenorhabditis elegans aging stress response

Hull, B. T.; Irby, I. M.; Anderson, A.; Miller, K. M.; Gardea, E. A.; Sutphin, G. L.

10.1101/2024.01.09.574889 — molecular biology — Posted on 2024-01-09

3405 Prevotella are major contributors of sialidases in the human vaginal microbiome.

Pelayo, P.; Hussain, F. A.; Werlang, C. A.; Wu, C.; Woolston, B. M.; Ribbeck, K.; Kwon, D. S.; Balskus, E. P.

10.1101/2024.01.09.574895 — microbiology — Posted on 2024-01-09

3406 Microbial communities associated with marine sponges from diverse geographic locations harbour biosynthetic novelty

Nowak, V. V.; Hou, P.; Owen, J. G.

10.1101/2024.01.09.574914 — microbiology — Posted on 2024-01-09

3407 Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice

Zamba-Campero, M.; Soliman, D.; Yu, H.; Lasseter, A. G.; Chang, Y.-Y.; Liu, J.; Aravind, L.; Jewett, M. W.; Storz, G.; Adams, P. P.

10.1101/2024.01.09.574855 — microbiology — Posted on 2024-01-09

3408 Lupus-associated innate receptors drive extrafollicular evolution of autoreactive B cells

Zhu, D. Y.-D.; Maurer, D. P.; Castrillon, C.; Deng, Y.; Mohamed, F. A. N.; Ma, M.; Schmidt, A. G.; Lingwood, D.; Carroll, M. C.

10.1101/2024.01.09.574739 — immunology — Posted on 2024-01-09

3409 Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the of AD-BXD Mouse Population

10.1101/2024.01.09.574219 — neuroscience — Posted on 2024-01-09

3410 Implementation of pupylation-based proximity labelling in plant biology reveals regulatory factors in cellulose biosynthesis

Zheng, S.; Khammy, O.; Noack, L.; De Meyer, A.; Khan, G.; De Winne, N.; Eeckhout, D.; van Damme, D.; Persson, S.

10.1101/2024.01.09.574788 — plant biology — Posted on 2024-01-09

3411 Human coronavirus HKU1 recognition of the TMPRSS2 host receptor

McCallum, M.; Park, Y.-J.; Stewart, C.; Sprouse, K. R.; Brown, J.; Tortorici, M. A.; Gibson, C.; Wong, E.; Ieven, M.; Telenti, A.; Veesler, D.

10.1101/2024.01.09.574565 — biochemistry — Posted on 2024-01-09

3412 Reannotation of the zebra finch genome reveals undiscovered transcriptional complexity

Richard, H.; Wiedenhoeft, J.; Scharff, C.; Adam, I.

10.1101/2024.01.09.574630 — molecular biology — Posted on 2024-01-09

3413 Stacking effects on mutation detection by T4 DNA ligation within dimeric DNA origami triangle barcodes for single-molecule nanopore analysis

Aboagye-Mensah, D.; Confederat, S.; Alammar, F.; Kailas, L.; Adedeji-Olulana, A. F.; Stopar, A.; Nicholson, A. W.; Thomson, N. H.; Actis, P.; Castronovo, M.

10.1101/2024.01.09.574918 — synthetic biology — Posted on 2024-01-09

3414 Entomological surveys and insecticide susceptibility profile of Aedes aegypti during the dengue outbreak in Sao Tome and Principe in 2022

Kamgang, B.; Acantara, J.; Tedjou, A.; Keumeni, C.; Yougang, A.; Ancia, A.; Bigirimana, F.; Clarke, S.; Gil, V. S.; Wondji, C.

10.1101/2024.01.07.574582 — zoology — Posted on 2024-01-09

3415 Endangered Przewalski's horse, Equus przewalskii, cloned from historically cryopreserved cells

Novak, B. J.; Ryder, O. A.; Houck, M. L.; Putnam, A. S.; Walker, K.; Russell, L.; Russell, B.; Walker, S.; Arenivas, S. S.; Aston, L.; Veneklasen, G.; Ivy, J. A.; Koepfli, K.-P.; Rusnak, A.; Simek, J.; Zhuk, A.; Phelan, R.

10.1101/2023.12.20.572538 — zoology — Posted on 2024-01-09

3416 A single changing hypernetwork to represent (social-)ecological dynamics

Gaucherel, C.; Cosme, M.; Nous, C.; Pommereau, F.

10.1101/2023.10.30.564699 — ecology — Posted on 2024-01-09

3417 Survival and Developmental Progression of Unselected Thymocytes in the Absence of the T Cell Adaptor Gads

Shalah, R.; Marzouk, M.; Hallumi, E.; Klopstock, N.; Yablonski, D.

10.1101/2023.07.05.547801 — immunology — Posted on 2024-01-09

3418 'Pscore' - A Novel Percentile-Based Metric to Accurately Assess Individual Deviations in Non-Gaussian Distributions of Quantitative MRI Metrics

Hafiz, R.; Irfanoglu, M. O.; Nayak, A.; Pierpaoli, C.

10.1101/2023.12.10.571016 — neuroscience — Posted on 2024-01-09

3419 Efficacy of Centers of Biomedical Research Excellence (CoBRE) Grants to Build Research Capacity in Underrepresented States

Schaller, M.

10.1101/2023.08.02.551624 — scientific communication and education — Posted on 2024-01-09

3420 Myosin VIII and XI isoforms interact with Agrobacterium VirE2 protein and help direct transport from the plasma membrane to the perinuclear region during plant transformation

Liu, N.; Lee, L.-Y.; Hsu, F.-Y.; Yu, Y.; Rao, P.; Gelvin, S. B.

10.1101/2023.03.06.531343 — plant biology — Posted on 2024-01-09

3421 High-Throughput DNA melt measurements enable improved models of DNA folding thermodynamics

Ke, Y.; Sharma, E.; Wayment-Steele, H. K.; Becker, W. R.; Ho, A.; Marklund, E.; Greenleaf, W. J.

10.1101/2024.01.08.574731 — biophysics — Posted on 2024-01-09

3422 Definition of regulatory elements and transcription factors controlling immune cell gene expression at single cell resolution using single nucleus ATAC-seq

Yang, P.; Corbett, R.; Daharsh, L.; Herrera Uribe, J.; Byrne, K. A.; Loving, C.; Tuggle, C. K.

10.1101/2024.01.09.574769 — bioinformatics — Posted on 2024-01-09

3423 A novel interpretable deep transfer learning combining diverse learnable parameters for improved T2D prediction based on single-cell gene regulatory networks

Alghamdi, S.; Turki, T.

10.1101/2023.09.07.556481 — bioinformatics — Posted on 2024-01-09

3424 A 39.8kb flavi-like virus uses a novel strategy for overcoming the RNA virus error threshold

Petrone, M. E.; Grove, J.; Mifsud, J. C. O.; Parry, R. H.; Marzinelli, E. M.; Holmes, E. C.

10.1101/2024.01.08.574764 — evolutionary biology — Posted on 2024-01-09

3425 Detection of Domestication Signals through the Analysis of the Full Distribution of Fitness Effects using Simulations

Vourlaki, I.-T.; Castellano, D.; Gutenkunst, R. N.; Ramos-Onsins, S. E.

10.1101/2022.08.24.505198 — evolutionary biology — Posted on 2024-01-09

3426 Local adaptation to an altitudinal gradient: the interplay between mean phenotypic trait variation and phenotypic plasticity in Mimulus laciniatus

Syrotchen, J. M.; Ferris, K. G.

10.1101/2023.08.02.551729 — evolutionary biology — Posted on 2024-01-09

3427 CST--Polymeraseα-primase solves a second telomere end-replication problem

Takai, H.; Aria, V.; Borges, P.; Yeeles, J. T. P.; de Lange, T.

10.1101/2023.10.26.564248 — cell biology — Posted on 2024-01-09

3428 The catalytic activity of microRNA Argonautes plays a modest role in microRNA star strand destabilization in C. elegans

Kotagama, K.; Grimme, A. L.; Braviner, L.; Yang, B.; Sakhawala, R.; Yu, G.; Benner, L. K.; Joshua-Tor, L.; McJunkin, K.

10.1101/2023.01.19.524782 — molecular biology — Posted on 2024-01-09

3429 The Emerging Role of 3-Hydroxyanthranilic Acid on C. elegans Aging Immune Function

Espejo, L. S.; DeNicola, D. D.; Chang, L. M.; Silbar, V. D.; Haskins, A. E.; Antenor, A. B.; Balsa, J. r.; Freitas, S.; Hamming, S.; Hull, B.; Dang, H.; Castro-Portuguez, R.; Sutphin, G. L.

10.1101/2024.01.07.574394 — immunology — Posted on 2024-01-09

3430 STING Licensing of Type I Dendritic Cells Potentiates Antitumor Immunity

Wang, J.; Li, S.; Wang, M.; Wang, X.; Chen, S.; Sun, Z.; Ren, X.; Huang, G.; Sumer, B. D.; Yan, N.; Fu, Y.-x.; Gao, J.

10.1101/2024.01.02.573934 — immunology — Posted on 2024-01-09

3431 Social cognitive regions of human association cortex are selectively connected to the amygdala

Edmonds, D.; Salvo, J. J.; Anderson, N.; Lakshman, M.; Yang, Q.; Kay, K.; Zelano, C.; Braga, R. M.

10.1101/2023.12.06.570477 — neuroscience — Posted on 2024-01-09

3432 Effects of dim light at night in C57BL6/J mice on recoveryafter spinal cord injury

Aldrich, J. C.; Scheinfeld, A. R.; Lee, S. E.; Dusenbery, K. J.; Mahach, K. M.; Van de Veire, B. C.; Fonken, L. K.; Gaudet, A. D.

10.1101/2023.09.15.557980 — neuroscience — Posted on 2024-01-09

3433 The activated plant NRC4 immune receptor forms a hexameric resistosome

Liu, F.; Yang, Z.; Wang, C.; Martin, R.; Qiao, W.; Carette, J. E.; Luan, S.; Nogales, E.; Staskawicz, B.

10.1101/2023.12.18.571367 — plant biology — Posted on 2024-01-09

3434 Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection

Burman, N.; Belukhina, S.; Depardieu, F.; Wilkinson, R. A.; Skutel, M.; Santiago-Frangos, A.; Graham, A. B.; Livenskyi, A.; Chechenina, A.; Morozova, N.; Zahl, T.; Henriques, W. S.; Buyukyoruk, M.; Rouillon, C.; Shyrokova, L.; Kurata, T.; Hauryliuk, V.; Severinov, K.; Groseille, J.; Thierry, A.; Koszul, R.; Tesson, F.; Bernheim, A.; Bikard, D.; Wiedenheft, B.; Isaev, A.

10.1101/2024.01.02.573894 — biochemistry — Posted on 2024-01-09

3435 Identification of genome safe harbor loci for human gene therapy based on evolutionary biology and comparative genomics

Quezada-Ramirez, M. A.; Loncar, S.; Campbell, M. A.; Parsi, K. M.; Gifford, R. J.; Kotin, R. M.

10.1101/2023.09.08.556857 — genetics — Posted on 2024-01-09

3436 Northeast India: Genetic Inconsistency across Ethnicity and Geography

Bankura, B.; Basak, B.; Singh, P. P.; Vanlalruata, A.; Chatterjee, A.; Ghosh, S.; Tamang, R.; Hazarika, M.; Chaubey, G.; Das, M.

10.1101/2024.01.09.574778 — evolutionary biology — Posted on 2024-01-09

3437 From juveniles to giants: Drivers of holobiont assembly in massive Porites

Scott, C. B.; Schott, R.; Matz, M. V.

10.1101/2024.01.09.574877 — ecology — Posted on 2024-01-09

3438 Intrinsic and extrinsic determinants of conditional localization of Mms6 to magnetosome organelles in Magnetospirillum magneticum AMB-1

Bickley, C. D.; Komeili, A.

10.1101/2024.01.08.574735 — cell biology — Posted on 2024-01-09

3439 Preferential apical infection of intestinal cell monolayers by SARS-CoV-2 is associated with damage to cellular barrier integrity: Implications for the physiopathology of COVID-19

Clemence, G.; Jeffrey, A.; Jonatane, A.; Mege, J.-L.; Omar Osman, I.; Devaux, C. A.

10.1101/2024.01.08.574642 — microbiology — Posted on 2024-01-09

3440 Deficiency in ribosome biogenesis causes streptomycin resistance and impairs motility in Salmonella

Lyu, Z.; Ling, Y.; Van Hoof, A.; Ling, J.

10.1101/2024.01.08.574728 — microbiology — Posted on 2024-01-09

3441 CD271 restrains the B1b cell antibody response in a T cell dependent manner

Lebel, M.-E.; Bonkoungou, C. A.; Thibault, J.; Rauch, J.; Alugupalli, K. R.; Melichar, H. J.

10.1101/2024.01.08.574733 — immunology — Posted on 2024-01-09

3442 Mathematical modeling of the influence of ACE I/D polymorphism on blood pressure and antihypertensive therapy

Kutumova, E.; Kovaleva, A.; Sharipov, R.; Lifshits, G.; Kolpakov, F.

10.1101/2024.01.09.574774 — systems biology — Posted on 2024-01-09

3443 Mutational biases contribute to the neutral complexification of protein interaction networks following gene duplication

Cisneros, A. F.; Nielly-Thibault, L.; Mallik, S.; Levy, E. D.; Landry, C. R.

10.1101/2023.10.31.565025 — systems biology — Posted on 2024-01-09

3444 Nationwide Inclusive Facilitator Training: Mindsets, Practices and Growth

Codding, D.; Yen, A. H.; Lewis, H.; Johnson-Ojeda, V.; Frey, R. F.; Hokanson, S. C.; Goldberg, B. B.

10.1101/2024.01.08.574770 — scientific communication and education — Posted on 2024-01-09

3445 Survey of the wheat mycobiome associated with leaf blotch and head blight diseases in Sweden

Kaur, H.; Vilvert, E.; Corrales Gutierrez, M. A.; Zhan, J.; Douchkov, D.; Desiderio, F.; Velez, H.; Bourras, S.

10.1101/2024.01.09.574850 — plant biology — Posted on 2024-01-09

3446 Mitochondrial respiration is essential for photosynthesis-dependent ATP supply of the plant cytosol

Vera-Vives, A. M.; Novel, P.; Zheng, K.; Tan, S.-l.; Schwarzlander, M.; Alboresi, A.; Morosinotto, T.

10.1101/2024.01.09.574809 — plant biology — Posted on 2024-01-09

3447 Identification of Arabidopsis phospholipase Ds involved in circadian clock alterations using CRISPR/Cas9-based multiplex editing

Kim, S.-C.; Nusinow, D. A.; Wang, X.

10.1101/2024.01.09.574824 — plant biology — Posted on 2024-01-09

3448 A conserved Pol II elongator SPT6L mediates Pol V transcription elongation to regulate RNA-directed DNA methylation in Arabidopsis

Liu, Y.; Shu, J.; Zhang, Z.; Ding, N.; Liu, J.; Liu, J.; Cui, Y.; Wang, C.; Chen, C.

10.1101/2024.01.09.574790 — plant biology — Posted on 2024-01-09

3449 Triterpene RDF: Developing a database of plant enzymes and transcription factors involved in triterpene biosynthesis using the Resource Description Framework

Tamura, K.; Chiba, H.; Bono, H.

10.1101/2024.01.08.574260 — plant biology — Posted on 2024-01-09

3450 Low parental conflict, no endosperm hybrid barriers, and maternal bias in genomic imprinting in selfing Draba species

Alling, R. M.; Bjerkan, K. N.; Bramsiepe, J.; Nowak, M. D.; Gustafsson, A. L. S.; Brochmann, C.; Brysting, A. K.; Grini, P. E.

10.1101/2024.01.08.574548 — plant biology — Posted on 2024-01-09

3451 RnaBench: A Comprehensive Library for In Silico RNA Modelling

Runge, F.; Farid, K.; Franke, J. K. H.; Hutter, F.

10.1101/2024.01.09.574794 — bioinformatics — Posted on 2024-01-09

3452 Measuring technical variability in Illumina DNA methylation microarrays

Butler, A.; Kras, J.; Chwalek, K.; Ramos, E. I.; Bishof, I.; Vogel, D.; Vera, D. L.

10.1101/2023.11.28.569087 — bioinformatics — Posted on 2024-01-09

3453 Menaquinone-specific oxidation by M. tuberculosis cytochrome bd is redox regulated by the Q-loop disulfide bond

van der Velden, T. T.; Waterham, C. Y. J.; Jeuken, L. J. C.

10.1101/2024.01.09.574813 — biochemistry — Posted on 2024-01-09

3454 Efficient overexpression and purification of SARS-CoV-2 Nucleocapsid proteins in Escherichia coli

Brudenell, E. L.; Pohare, M. B.; Zafred, D.; Phipps, J.; Hornsby, H. R.; Darby, J.; Dai, J.; Liggett, E.; Cain, K.; Barran, P. E.; de Silva, T. I.; Sayers, J. R.

10.1101/2024.01.08.574531 — biochemistry — Posted on 2024-01-09

3455 Sound-seeking before and after hearing loss in mice

Mai, J.; Gargiullo, R.; Zheng, M.; Esho, V.; Hussein, O. E.; Pollay, E.; Bowe, C.; Williamson, L. M.; McElroy, A. F.; Goolsby, W. N.; Brooks, K. A.; Rodgers, C. C.

10.1101/2024.01.08.574475 — animal behavior and cognition — Posted on 2024-01-09

3456 Long-read sequencing reveals novel structural variation markers for key agronomic and quality traits of soybean

Wang, Z.; Belay, K.; Paterson, J.; Bewick, P.; Singer, W.; Song, Q.; Zhang, B.; Li, S.

10.1101/2024.01.09.574864 — genomics — Posted on 2024-01-09

3457 The earliest allopolyploidization in tracheophytes revealed by phylotranscriptomics and morphology of Selaginellaceae

Kang, J.-S.; Yu, J.-g.; Xiang, Q.-P.; Zhang, X.-C.

10.1101/2024.01.08.574748 — genomics — Posted on 2024-01-09

3458 Approaching pathogenic Clostridia from a One Health perspective

Cersosimo, L.; Worley, J. N.; Bry, L.

10.1101/2024.01.08.574718 — genomics — Posted on 2024-01-09

3459 Spatial Transcriptomics Sequencing of Mouse Liver at 2 Micron Resolution Using a Novel Spatial DNA Chip

Ding, X.; Hoff, K.; Swaminathan, R.; Pollom, S.; Huang, T.; Li, X.; Zhou, G.; Bai, Z.; Yu, S.; Koutrouli, M.; Jensen, L. J.; Crnogorac, F.; Crnogorac, F.; Yu, S.; McGall, G.; Edwards, J.; Zhou, W.

10.1101/2024.01.08.574734 — genomics — Posted on 2024-01-09

3460 A mouse model to study glutathione limitation in vivo

Timson, R. C.; Khan, A.; Uygur, B.; Saad, M.; Yeh, H.-W.; DelGaudio, N. L.; Weber, R.; Alwaseem, H.; Gao, J.; Yang, C.; Birsoy, K.

10.1101/2024.01.08.574722 — genetics — Posted on 2024-01-09

3461 Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in non-alcoholic steatohepatitis and reversed by alternate day fasting

Tripathi, M.; Gauthier, K.; Sandireddy, R.; Zhou, J.; Gupta, P.; Sakthivel, S.; Teo, W. W.; Naing, Y. T.; Arul, K.; Tikno, K.; Park, S.-H.; Wu, Y.; Wang, L.; Bay, B. H.; Sun, L.; Giguere, V.; Chow, P. K. H.; GHOSH, S.; McDonnell, D. P.; Yen, P. M.; Singh, B. K.

10.1101/2021.11.16.468891 — molecular biology — Posted on 2024-01-09

3462 Metatranscriptomic analysis reveals synergistic activities of comammox and anammox bacteria in full-scale attached growth nitrogen removal system.

Johnston, J.; Vilardi, K.; Cotto, I.; Sudarshan, A.; Bian, K.; Klaus, S.; Bachmann, M.; Parsons, M.; Wilson, C.; Bott, C.; Pinto, A.

10.1101/2024.01.08.574720 — microbiology — Posted on 2024-01-09

3463 Peptidoglycan fragment release and NOD activation by commensal Neisseria species from humans and other animals

Harris-Jones, T. N.; Chan, J. M.; Hackett, K. T.; Weyand, N. J.; Schaub, R. E.; Dillard, J. P.

10.1101/2024.01.09.574863 — microbiology — Posted on 2024-01-09

3464 Nature AND Nurture: Enabling formate-dependent growth in Methanosarcina acetivorans

Bao, J.; Somvanshi, T.; Tian, Y.; Laird, M.; Garcia, P. S.; Schoene, C.; Rother, M.; Borrel, G.; Scheller, S.

10.1101/2024.01.08.574737 — microbiology — Posted on 2024-01-09

3465 Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection

Simmons, S. R.; Herring, S. E.; Tchalla, E. Y. I.; Lenhard, A. P.; Bhalla, M.; Bou Ghanem, E. N.

10.1101/2024.01.08.574741 — immunology — Posted on 2024-01-09

3466 Structured behavioral data format: An NWB extension standard for task-based behavioral neuroscience experiments

Ly, R.; Avaylon, M.; Wulf, M.; Kepecs, A.; Ruebel, O.

10.1101/2024.01.08.574597 — neuroscience — Posted on 2024-01-09

3467 Lifelong molecular consequences of high Glucocorticoids exposure during development

Choi, M.-K.; Cook, A.; Mungikar, K.; Eachus, H.; Tochwin, A.; Linke, M.; Gerber, S.; Ryu, S.

10.1101/2023.02.13.528363 — neuroscience — Posted on 2024-01-09

3468 Late-life isoleucine restriction promotes physiological and molecular signatures of healthy aging

Yeh, C.-Y.; Chini, L. C. S.; Davidson, J. W.; Garcia, G. G.; Gallagher, M. S.; Freichels, I. T.; Calubag, M. F.; Rodgers, A. C.; Green, C. L.; Babygirija, R.; Sonsalla, M. M.; Pak, H. H.; Trautman, M.; Hacker, T. A.; Miller, R. A.; Simcox, J.; Lamming, D.

10.1101/2023.02.06.527311 — physiology — Posted on 2024-01-09

3469 Lateral Flow Assays Biotesting by Utilizing Plasmonic Nanocrystals Made of Inexpensive Metals - Replacing Gold

Bahamondes Lorca, V. A.; Avalos-Ovando, O. R.; Sikeler, C.; Santiago, E. Y.; Skelton, E.; Wang, Y.; Yang, R.; Cimatu, K. L. A.; Baturina, O.; Wang, Z.; Liu, J.; Slocik, J. M.; Wu, S.; Ma, D.; Pastukhov, A. I.; Kabashin, A.; Kordesch, M. E.; Govorov, A.

10.1101/2024.01.08.574723 — biophysics — Posted on 2024-01-09

3470 GLDADec: marker-gene guided LDA modelling for bulk gene expression deconvolution

Azuma, I.; Mizuno, T.; Kusuhara, H.

10.1101/2024.01.08.574749 — bioinformatics — Posted on 2024-01-09

3471 Ultrasound-Driven Programmable Artificial Muscles

Shi, Z.; Zhang, Z.; Ahmed, D.

10.1101/2024.01.08.574699 — bioengineering — Posted on 2024-01-09

3472 Methane and ethane production rates by methyl-coenzyme M reductase in cell extracts from different methanogens

Nguyen, V. P. T.; Keller, S.; Scheller, S.

10.1101/2024.01.08.574666 — biochemistry — Posted on 2024-01-09

3473 Genome-wide patterns of non-coding sequence variation in the major fungal pathogen Aspergillus fumigatus

Brown, A.; Steenwyk, J. L.; Rokas, A.

10.1101/2024.01.08.574724 — evolutionary biology — Posted on 2024-01-09

3474 Protein SUMOylation promotes cAMP-independent EPAC1 activation

Yang, W.; Mei, F.; Lin, W.; White, M. A.; Li, L.; Li, Y.; Pan, S.; Cheng, X.

10.1101/2024.01.08.574738 — cell biology — Posted on 2024-01-09

3475 Plasmodium falciparum mitochondrial complex III, the target of atovaquone, is essential for progression to the transmissible sexual stages.

Sheokand, P. K.; Muhleip, A.; Sheiner, L.

10.1101/2024.01.09.574740 — cell biology — Posted on 2024-01-09

3476 Interactors of sacsin DNAJ domain identify function in organellar transport and membrane composition relevant to ARSACS pathogenesis

Pare, A. M.; Cheng-Boivin, Z.; Dabbaghizadeh, A.; Minotti, S.; Durham, H. D.; Gentil, B. J.

10.1101/2024.01.08.574743 — cell biology — Posted on 2024-01-09

3477 Phosphorylation inhibits intramolecular interactions, DNA-binding and protein interactions of Claspin through disordered/ structured conformation transition

You, Z.; Hsiao, H.-W.; Yang, C.-C.; Goto, H.; Masai, H.

10.1101/2024.01.08.574761 — molecular biology — Posted on 2024-01-09

3478 Release of extracellular DNA by Pseudomonas species as a major determinant for biofilm switching and an early indicator for cell population control

Kakahi, F. B.; Martinez Alvarez, J. A.; Avitia, F. M.; Telek, S.; Volke, D. C.; Wirth, N. T.; Nikel, P. I.; Delvigne, F.

10.1101/2021.02.11.430776 — microbiology — Posted on 2024-01-09

3479 The SV40 virus enhancer functions as a somatic hypermutation-targeting element with potential oncogenic activity

Senigl, F.; Soikkeli, A. I.; Prost, S.; Schatz, D. G.; Slavkova, M.; Hejnar, J.; Alinikula, J.

10.1101/2024.01.09.574829 — microbiology — Posted on 2024-01-09

3480 Characterization and genomic analysis of the Lyme disease spirochete bacteriophage phiBB-1

Faith, D. R.; Kinnersley, M.; Brooks, D. M.; Drecktrah, D.; Hall, L. S.; Luo, E.; Santiago-Frangos, A.; Wachter, J.; Samuels, S.; Secor, P. R.

10.1101/2024.01.08.574763 — microbiology — Posted on 2024-01-09

3481 Prevotella timonensis degrades the vaginal epithelial glycocalyx through high fucosidase and sialidase activities

Segui Perez, C.; De Jongh, R.; Jonkergouw, R.; Pelayo, P.; Balskus, E. P.; Zomer, A.; Strijbis, K.

10.1101/2024.01.09.574844 — microbiology — Posted on 2024-01-09

3482 MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in Drosophila gut during inflammation

Arias-Rojas, A.; Arifah, A.; Angelidou, G.; Alshaar, B.; Schombel, U.; Forest, E.; Frahm, D.; Brinkmann, V.; Paczia, N.; Beisel, C.; Gisch, N.; Iatsenko, I.

10.1101/2024.01.09.574795 — microbiology — Posted on 2024-01-09

3483 Regulators H-NS and LeuO inversely control swarming motility and biofilm formation in Vibrio parahaemolyticus

Bhide, S. M.; Tague, J.; Andrews, J. A.; Boas Lichty, K.; Boyd, E. F.

10.1101/2024.01.09.574875 — microbiology — Posted on 2024-01-09

3484 Mapping the tRNA Modification Landscape of Bartonella henselae Houston I and Bartonella quintana Toulouse

Quaiyum, S.; Sun, J.; Marchand, V.; Sun, G.; Reed, C. J.; Motorin, Y.; Dedon, P.; Minnick, M.; de Crecy-Lagard, V.

10.1101/2024.01.08.574729 — microbiology — Posted on 2024-01-09

3485 Timing the cerebellum and its connectivity within the social brain

Ciricugno, A.; Ferrari, C.; Battelli, L.; Cattaneo, Z.

10.1101/2024.01.09.574775 — neuroscience — Posted on 2024-01-09

3486 Enhancement of Mediodorsal Thalamus Rescues Aberrant Belief Dynamics in a Novel Mouse Model for Schizophrenia

zhou, T.; Ho, Y.-Y.; Lee, R. X.; Fath, A. B.; He, K.; Scott, J.; Bajwa, N.; Hartley, N. D.; Wilde, J.; Gao, X.; Li, C.; Hong, E.; Nassar, M. R.; Wimmer, R. D.; Singh, T.; Halassa, M.; Feng, G.

10.1101/2024.01.08.574745 — neuroscience — Posted on 2024-01-09

3487 Do Topographic Deep ANN Models of the Primate Ventral Stream Predict the Perceptual Effects of Direct IT Cortical Interventions?

Schrimpf, M.; McGrath, P.; Margalit, E.; DiCarlo, J. J.

10.1101/2024.01.09.572970 — neuroscience — Posted on 2024-01-09

3488 Prefrontal cortical dynorphin peptidergic transmission constrains threat-driven behavioral and network states

Wang, H.; Flores, R. J.; Yarur, H. E.; Limoges, A.; Bravo-Rivera, H.; Casello, S. M.; Loomba, N.; Enriquez-Traba, J.; Arenivar, M.; Wang, Q.; Ganley, R.; Ramakrishnan, C.; Fenno, L. E.; Kim, Y.; Deisseroth, K.; Or, G.; Dong, C.; Hoon, M. A.; Tian, L.; Tejeda, H. A.

10.1101/2024.01.08.574700 — neuroscience — Posted on 2024-01-09

3489 Dopaminergic Changes in the Subgenual Cingulate Cortex in Dementia with Lewy Bodies Associates with Presence of Depression

Gliaudelyte, L.; Rushton, S. P.; Berlinguer-Palmini, R.; Thomas, A.; Morris, C. M.

10.1101/2024.01.09.574871 — neuroscience — Posted on 2024-01-09

3490 Emergence of multiple spontaneous coherent subnetworks from a single configuration of human connectome-coupled oscillators model

Torres, F. A.; Otero, M.; Lea-Carnall, C. A.; Cabral, J.; Weinstein, A.; El-Deredy, W.

10.1101/2024.01.09.574845 — neuroscience — Posted on 2024-01-09

3491 The ventral hippocampus and nucleus accumbens underlie long-term social memory about female conspecifics in male mice

Watarai, A.; Ishida, K.; Okuyama, T.

10.1101/2024.01.08.574751 — neuroscience — Posted on 2024-01-09

3492 Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer's Disease

Bansal, V. A.; Tan, J. M.; Soon, H. R.; Zainolabidin, N. B.; Saito, T.; Ch'ng, T. H.

10.1101/2024.01.08.574293 — neuroscience — Posted on 2024-01-09

3493 The landscape of glial pathology and T-call response in Parkinson's substantia nigra

Jakubiak, K.; Paryani, F.; Kannan, A.; Lee, J.; Madden, N.; Li, J.; Chen, D.; Mahajan, A.; Xia, S.; Flowers, X.; Menon, V.; Sulzer, D.; Goldman, J. E.; Sims, P. A.; Al-Dalahmah, O.

10.1101/2024.01.08.574736 — neuroscience — Posted on 2024-01-09

3494 Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in Amyotrophic Lateral Sclerosis

Wong, J.; Blazev, R.; Ng, Y.-K.; Goodman, C. A.; Montogmery, M. K.; Watt, K. I.; Carl, C. S.; Watt, M. J.; Voldstedlund, C. T.; Richter, E. A.; Crouch, P. J.; Steyn, F. J.; Ngo, S. T.; Parker, B. L.

10.1101/2024.01.08.574551 — physiology — Posted on 2024-01-09

3495 RFX6 at locus 6q22 confers metastasis and drug resistance in prostate cancer

zhong, M.; tian, P.; xu, w.; zhang, q.; Wang, Z.; Liang, L.; Zhang, Q.; Lu, Y.; Wei, G.-H.

10.1101/2024.01.08.574758 — cancer biology — Posted on 2024-01-09

3496 Signaling events at TMEM doorways provide potential targets for inhibiting breast cancer dissemination

Surve, C. R.; Duran, C. L.; Ye, X.; Chen, X.; Lin, Y.; Harney, A. S.; Wang, Y.; Sharma, V. P.; Stanley, E. R.; McAuliffe, J. C.; Entenberg, D.; Oktay, M. H.; Condeelis, J. S.

10.1101/2024.01.08.574676 — cancer biology — Posted on 2024-01-09

3497 Aberrant non-canonical NF-kappaB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

Ang, D. A.; Carter, J.-M.; Deka, K.; TAN, J. H. L.; Zhou, J.; Chen, Q.; Chng, W. J.; Harmston, N.; Li, Y.

10.1101/2024.01.09.574787 — cancer biology — Posted on 2024-01-09

3498 User-friendly Oblique Plane Microscopy on a fully functional commercially available microscope base

Sirinakis, G.; Allgeyer, E. S.; Nashchekin, D.; St Johnston, D.

10.1101/2024.01.09.574832 — biophysics — Posted on 2024-01-09

3499 RNA regulates cohesiveness and porosity of a biological condensate

Chou, H.-Y.; Aksimentiev, A.

10.1101/2024.01.09.574811 — biophysics — Posted on 2024-01-09

3500 Transient interactions between the fuzzy coat and the cross-β core of brain-derived Aβ42 filaments

Milanesi, M.; Brotzakis, Z. F.; Vendruscolo, M.

10.1101/2024.01.08.574772 — biophysics — Posted on 2024-01-09

3501 ScGOclust: leveraging gene ontology to compare cell types across distant species using scRNA-seq data

Song, Y.; Hu, Y.; Dow, J. A. T.; Perrimon, N.; Papatheodorou, I.

10.1101/2024.01.09.574675 — bioinformatics — Posted on 2024-01-09

3502 PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration

Wieder, C.; Cooke, J.; Poupin, N.; Frainay, C.; Bowler, R.; Kechris, K.; Jourdan, F.; Lai, R.; Ebbels, T.

10.1101/2024.01.09.574780 — bioinformatics — Posted on 2024-01-09

3503 Annotations of four high-quality indigenous chicken genomes identify more than one thousand missing genes in sub-telomeric regions with high G/C contents

Wu, S.; Dou, T.; Yuan, S.; Yan, S.; Xu, Z.; Liu, Y.; Jian, Z.; Zhao, J.; Zhao, R.; Zi, X.; Gu, D.; Liu, L.; Li, Q.; Wu, D.-D.; Su, Z.; Jia, J.; Ge, C.; Wang, K.

10.1101/2024.01.08.574549 — bioinformatics — Posted on 2024-01-09

3504 shRNAI: a deep neural network for the design of highly potent shRNAs

Park, S.; Park, S.-H.; Oh, J.-S.; Noh, Y.-K.; Hur, J. K.; Nam, J.-W.

10.1101/2024.01.09.574789 — bioinformatics — Posted on 2024-01-09

3505 scDirect: key transcription factor identification for directing cell state transitions based on single-cell multi-omics data

Li, C.; Chen, S.; Chen, Y.; Bian, H.; Hao, M.; Wei, L.; Zhang, X.

10.1101/2024.01.08.574757 — bioinformatics — Posted on 2024-01-09

3506 PIRCHE application versions 3 and 4 lead to equivalent T cell epitope mismatch scores in solid organ and stem cell transplantation modules

Matern, B. M.; Niemann, M.

10.1101/2024.01.09.574785 — bioinformatics — Posted on 2024-01-09

3507 Quantifying the advantage of multimodal data fusion for survival prediction in cancer patients

Nikolaou, N.; Salazar, D.; RaviPrakash, H.; Goncalves, M.; Mulla, R.; Burlutskiy, N.; Markuzon, N.; Jacob, E.

10.1101/2024.01.08.574756 — bioinformatics — Posted on 2024-01-09

3508 Multiscale characterization of the mechanics of curved fibered structures with application to biological materials

Sanz-Herrera, J. A.; Apolinar-Fernandez, A.; Jimenez-Aires, A.; Perez-Alcantara, P.; Dominguez, J.; Reina-Romo, E.

10.1101/2024.01.09.574800 — bioengineering — Posted on 2024-01-09

3509 Discovery and binding mode of a small molecule inhibitor of the apo form of human TDO2

Lotz-Jenne, C.; Lange, R.; Cren, S.; Bourquin, G.; Goglia, L.; Kimmerlin, T.; Wicki, M.; Mueller, M.; Artico, N.; Ackerknecht, S.; Joesch, C.; Mac Sweeney, A.

10.1101/2024.01.09.574827 — biochemistry — Posted on 2024-01-09

3510 Mutation of two intronic nucleotide alters RNA structure and dynamics, inhibiting MBNL1 and RBFOX1 regulated splicing of the Insulin Receptor

Nowzari, Z.; Hale, M.; Ellis, J.; Biaesch, S.; Vangaveti, S.; Reddy, K.; Chen, A.; Berglund, A.

10.1101/2024.01.08.574689 — biochemistry — Posted on 2024-01-09

3511 Quinone extraction drives atmospheric carbon monoxide oxidation in bacteria

Kropp, A.; Gillett, D. L.; Venugopal, H.; Gonzalvez, M. A.; Lingford, J. P.; Barlow, C. K.; Zhang, J.; Greening, C.; Grinter, R.

10.1101/2024.01.09.574806 — biochemistry — Posted on 2024-01-09

3512 Pregnancy affects flight behavior in big brown bats (Eptesicus fuscus)

Calistri-Yeh, A.; Young, V. K. H.; Klingerman, M.; Kloepper, L. N.

10.1101/2024.01.08.574405 — animal behavior and cognition — Posted on 2024-01-09

3513 De novo annotation of the wheat pangenome reveals complexity and diversity of the hexaploid wheat pan-transcriptome

White, B.; LUX, T.; Rusholme-Pilcher, R.; Juhasz, A.; Kaithakottil, G.; Duncan, S.; Simmonds, J.; Rees, H.; Wright, J.; Colmer, J.; Ward, S.; joynson, R.; Coombes, B.; Irish, N.; Henderson, S.; Baker, T.; Chapman, H.; Catchpole, L.; Gharbi, K.; Okada, M.; Handa, H.; Nasuda, S.; Shimizu, K.; Gundlach, H.; Lang, D.; Naamati, G.; Legg, E.; Bharti, A.; Colgrave, M.; Haerty, W. `; Uauy, C. `; Swarbreck, D.; Borrill, P.; Poland, J.; Krattinger, S.; Stein, N.; Mayer, K. F. X.; Pozniak, C.; Spannagl, M.; Hall, A.

10.1101/2024.01.09.574802 — genomics — Posted on 2024-01-09

3514 Hydrophobic bulk conservation and genetic code determine the pattern of prokaryotic genome organization

Teng, W.; Zhou, Y.; Zheng, L.; Xu, Y.; Rao, Y.; Chen, S.; Xia, T.; Shu, W.; Chen, M.

10.1101/2024.01.09.574814 — evolutionary biology — Posted on 2024-01-09

3515 A network optimisation condition uncovers the role offunctional groups in the feasibility and dynamical stability of microbial model ecosystems.

Buchenel, L.; Bonhoeffer, S.; Pascual-Garcia, A.

10.1101/2024.01.09.574826 — ecology — Posted on 2024-01-09

3516 Deep rhizospheres extend the nitrogen cycle meters below the base of soil into weathered bedrock

Crutchfield-Peters, K. L.; Rempe, D. M.; Tune, A. K.; Dawson, T. E.

10.1101/2024.01.08.574278 — ecology — Posted on 2024-01-09

3517 Altered Extracellular Matrix Structure and Elevated Stiffness in a Brain Organoid Model for Disease

Karlinski Zur, M.; Bhattacharya, B.; Ben Dor, S.; Solomonov, I.; Savidor, A.; Sapir, T.; Harris, T.; Olender, T.; Sagi, I.; Schmidt, R.; Schwarz, J.; Buxboim, A.; Reiner, O.

10.1101/2024.01.09.574777 — developmental biology — Posted on 2024-01-09

3518 Appropriate glycemic management protects the germline but not uterine environment in type 1 diabetes

Zhao, A.; Jiang, H.; Palomares, A. R.; Larsson, A.; He, W.; Grunler, J.; Zheng, X.; Rodriguez-Wallberg, K.; Catrina, S.-B.; Deng, Q.

10.1101/2024.01.09.574805 — developmental biology — Posted on 2024-01-09

3519 Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis

Peters, F.; Brodesser, S.; Kruse, K.; Drexler, H. C. A.; Hu, J.; Lukas, D.; von Stebut, E.; Kroenke, M.; Niessen, C. M.; Wickstrom, S. A.

10.1101/2024.01.09.574628 — developmental biology — Posted on 2024-01-09

3520 Tcf12 controls dynamic calvarial bone growth and motor learning in mice

Yamada, T.; Anderson-Ramirez, J.; Gao, L.; Chen, P.; Zhang, M.; Guo, T.; Feng, J.; Ho, T.-V.; Vorobyova, I.; Santa Maria, N.; Jacobs, R.; Chen, J.-F.; Chai, Y.

10.1101/2024.01.09.574781 — developmental biology — Posted on 2024-01-09

3521 SURF2 is a MDM2 antagonist in triggering the nucleolar stress response

Tagneres, S.; Espirito-Santo, P.; Radermecker, J.; Rinaldi, D.; Froment, C.; Provost, Q.; Capeille, S.; Watkins, N. J.; Marcoux, J.; Gleizes, P.-E.; Marcel, V.; Plisson-Chastang, C.; LEBARON, S.

10.1101/2024.01.09.574617 — cell biology — Posted on 2024-01-09

3522 Feedback control of the heat shock response by spatiotemporal regulation of Hsp70

Garde, R.; Dea, A.; Herwig, M. F.; Pincus, D.

10.1101/2024.01.09.574867 — cell biology — Posted on 2024-01-09

3523 Primary oocytes with cellular senescence features are involved in ovarian aging in mice

Yan, H.; Diaz Miranda, E. A.; Jin, S.; Wilson, F.; An, K.; Godbee, B.; Zheng, X.; Brau-Rodriguez, A. R.; Lei, L.

10.1101/2024.01.08.574768 — cell biology — Posted on 2024-01-09

3524 Key determinants of CRISPR/Cas9 induced inversions in tomato

Grubben, J.; Bijsterbosch, G.; Visser, R. G. F.; Schouten, H. J.

10.1101/2024.01.09.574821 — molecular biology — Posted on 2024-01-09

3525 The astrovirus N-terminal nonstructural protein anchors replication complexes to the perinuclear ER membranes

Ali, H.; Noyvert, D.; Hankinson, J.; Lindsey, G.; Lulla, V.

10.1101/2024.01.09.574783 — microbiology — Posted on 2024-01-09

3526 The INO80 chromatin remodeling complex regulates histone H2A.Z mobility and the G1-S transition in oligodendrocyte precursors

Wright, J. L.; Jiang, Y.; Nayar, S. G.; Cutillas, P.; Rajeeve, V.; Li, H.; Richardson, W. D.

10.1101/2024.01.09.574847 — neuroscience — Posted on 2024-01-09

3527 Hippocampal trauma memory processing conveying susceptibility to traumatic stress

Dirven, B. C. J.; Melis, L. v.; Daneva, T.; Dillen, L.; Homberg, J. R.; Kozicz, T.; Henckens, M. J. A. G.

10.1101/2024.01.08.574632 — neuroscience — Posted on 2024-01-09

3528 Stimulus-induced gamma sources weaken but not shrink with healthy aging in human EEG

Kumar, W. S.; Sharma, K.; Ray, S.

10.1101/2024.01.09.574816 — neuroscience — Posted on 2024-01-09

3529 Continuous structural neuroplasticity during motor learning - a diffusion MRI study

Friedman, N.; Malovani, C.; Perets, I.; Kenin, E.; Bernstein-Eliav, M.; Tavor, I.

10.1101/2024.01.09.574830 — neuroscience — Posted on 2024-01-09

3530 Two-photon all-optical electrophysiology for the dissection of larval zebrafish brain functional connectivity

Turrini, L.; Ricci, P.; Sorelli, M.; de Vito, G.; Marchetti, M.; Vanzi, F.; Pavone, F. S.

10.1101/2024.01.08.574771 — neuroscience — Posted on 2024-01-09

3531 JNK1 And Downstream Signalling Hubs Regulate Anxiety-Like Behaviours In A Zebrafish Larvae Phenotypic Screen

Hong, Y.; Sourander, C.; Hackl, B.; Patton, J.; John, J.; Paatero, I.; Coffey, E.

10.1101/2024.01.09.574843 — pharmacology and toxicology — Posted on 2024-01-09

3532 Single molecule delivery into living cells

Chau, C.; Maffeo, C.; Aksimentiev, A.; Radford, S.; Hewitt, E.; Actis, P.

10.1101/2024.01.09.574652 — biophysics — Posted on 2024-01-09

3533 Photo-crosslinking hERG channels causes a U.V.-driven, state-dependent disruption of kinetics and voltage dependence of activation

Codding, S. J.; Trudeau, M. C.

10.1101/2024.01.09.574834 — biophysics — Posted on 2024-01-09

3534 Supergene evolution via gain of auto-regulation

VanKuren, N. W.; Sheikh, S. I.; Massardo, D.; Lu, W.; Kronforst, M. R.

10.1101/2024.01.09.574839 — evolutionary biology — Posted on 2024-01-09

3535 A multi-host mechanistic model of African swine fever emergence and control in Romania

Hayes, B. H.; Vergne, T.; Rose, N.; Mortasivu, C.; Andraud, M.

10.1101/2024.01.09.574784 — ecology — Posted on 2024-01-09

3536 Hierarchical Ordination, A unifying framework for drivers of community processes

O'Hara, R. B.; van der Veen, B.

10.1101/2024.01.08.574701 — ecology — Posted on 2024-01-09

3537 An internally controlled system to study microtubule network diversification links tubulin evolution to the use of distinct microtubule regulators

Kennard, A. S.; Velle, K. B.; Ranjan, R.; Schulz, D.; Fritz-Laylin, L.

10.1101/2024.01.08.573270 — cell biology — Posted on 2024-01-09

3538 Activity of Salmonella SPI-1 inhibits the TLR4-dependent transcriptional but not translational response during macrophage infection

Wood, G.; Johnson, R.; Brember, M.; Lastovka, F.; Tourlomousis, P.; Bryant, C.; Chung, B. Y.-W.

10.1101/2024.01.08.574706 — molecular biology — Posted on 2024-01-09

3539 WITHDRAWN: Release of extracellular DNA by Pseudomonas species as a major determinant for biofilm switching and an early indicator for cell population control

Bajoul Kakahi, F.; Martinez, J. A.; Moreno Avitia, F.; Telek, S.; Volke, D. C.; Wirth, N.; Nikel, P. I.; Frank, D.

10.1101/2023.12.09.570746 — microbiology — Posted on 2024-01-09

3540 The Art of Brainwaves: A Survey on Event-Related Potential Visualization Practices

Mikheev, V.; Skukies, R.; Ehinger, B.

10.1101/2023.12.20.572507 — neuroscience — Posted on 2024-01-09

3541 Single cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes

G V S, D.; Dani, A.

10.1101/2024.01.08.574704 — neuroscience — Posted on 2024-01-09

3542 HUB-DT: A tool for unsupervised behavioural discovery and analysis

Lindsay, A. J.

10.1101/2024.01.08.574696 — neuroscience — Posted on 2024-01-09

3543 Vestibular prepulse inhibition of the human blink reflex

Ciocca, M.; Hosli, S.; Hadi, Z.; Mahmud, M.; Tai, Y.; Seemungal, B. M.

10.1101/2024.01.09.574842 — neuroscience — Posted on 2024-01-09

3544 Designing host-associated microbiomes using the consumer/resource model

Plata, G. D.; Krishnamurthy, M.; Herron, L.; Dixit, P.

10.1101/2023.04.28.538625 — systems biology — Posted on 2024-01-09

3545 Electrostatic Trade-Off between Mesophilic Stability and Adaptation in Halophilic Proteins

Herrero-Alfonso, P.; Pejenaute, A.; Millet, O.; Ortega, G.

10.1101/2024.01.08.574673 — biophysics — Posted on 2024-01-09

3546 Generalizable Quantum Computing Pipeline for Real World Drug Discovery

Li, W.; Yin, Z.; Li, X.; Ma, D.; Zhang, Z.; Zou, C.; Bu, K.; Dai, M.; Yue, J.; Chen, Y.; Zhang, X.; Zhang, S.

10.1101/2024.01.08.574600 — bioinformatics — Posted on 2024-01-09

3547 Evaluating topography of mutational signatures with SigProfilerTopography

Otlu, B.; Alexandrov, L. B.

10.1101/2024.01.08.574683 — bioinformatics — Posted on 2024-01-09

3548 Inferring strain-level mutational drivers of phage-bacteria interaction phenotypes

Lucia-Sanz, A.; Peng, S.; Leung, J.; Gupta, A.; Meyer, J. R.; Weitz, J. S.

10.1101/2024.01.08.574707 — bioinformatics — Posted on 2024-01-09

3549 Genetic sex determination in three closely related hydrothermal vent gastropods, including one species with intersex individuals

Castel, J.; Pradillon, F.; Cueff, V.; Daguin-Thiebaut, C.; Ruault, S.; Mary, J.; Hourdez, S.; Jollivet, D.; Broquet, T.

10.1101/2023.04.11.536409 — evolutionary biology — Posted on 2024-01-09

3550 Unraveling the seasonal dynamics of ixodid ticks: A flexible matrix population model with delayed life history effects

Vindenes, Y.; Mysterud, A.

10.1101/2024.01.08.574636 — ecology — Posted on 2024-01-09

3551 Modularity of the segmentation clock and morphogenesis

Hammond, J. E.; Baker, R. E.; Verd, B.

10.1101/2024.01.08.574679 — developmental biology — Posted on 2024-01-09

3552 Membrane cliffs are giant, recursive platforms that drive calcium and protein kinase signaling for cell growth

Trerotola, M.; Relli, V.; Tripaldi, R.; Simeone, P.; Guerra, E.; Sacchetti, A.; Ceci, M.; Pantalone, L.; Ciufici, P.; Moschella, A.; Caiolfa, V.; Zamai, M.; Alberti, S.

10.1101/2024.01.08.574622 — cell biology — Posted on 2024-01-09

3553 Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development

Courreges, C. J.; Davenport, E. C.; Bilanges, B.; Rebollo-Gomez, E.; Hukelmann, J.; Schoenfelder, P.; Edgar, J. R.; Sansom, D.; Scudamore, C.; Roychoudhuri, R.; Garden, O. A.; Vanhaesebroeck, B.; Okkenhaug, K.

10.1101/2024.01.08.574346 — immunology — Posted on 2024-01-09

3554 The predictive outfielder: a critical test across gravities

Aguado, B.; Lopez-Moliner, J.

10.1101/2024.01.08.574654 — neuroscience — Posted on 2024-01-09

3555 Evaluation of the effects of ripening-related genes on fruit metabolites and the associated regulatory mechanisms in tomato

Niu, Q.; Jia, H.; Xu, Y.; Deng, Y.; Xie, Y.; Gao, Z.; Lang, Z.

10.1101/2024.01.08.574695 — plant biology — Posted on 2024-01-09

3556 How mucilage helps seeds from being washed away? A mechanical interpretation of myxodiaspory using rheology

Bhaskaran, K.; Puchalapalli, S.; Deshpande, A. P.; Varughese, S.

10.1101/2024.01.08.574694 — physiology — Posted on 2024-01-09

3557 Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response

Hayes, B. H.; Wang, M.; Zhu, H.; Phan, S. H.; Andrechak, J. C.; Chang, A. H.; Dooling, L. J.; Tobin, M. P.; Marchena, T.; Discher, D.

10.1101/2023.04.02.535275 — cancer biology — Posted on 2024-01-09

3558 A comparative study of influenza A M2 protein conformations in DOPC/DOPS liposomes and in native E. coli membranes

Sanders, G.; Borbat, P. P.; Georgieva, E. R.

10.1101/2024.01.08.574681 — biophysics — Posted on 2024-01-09

3559 Coordinated molecular and ecological adaptations underlie a highly successful parasitoid

Pang, L.; Fang, G.; Liu, Z.; Dong, Z.; Chen, J.; Feng, T.; Zhang, Q.; Sheng, Y.; Lu, Y.; Wang, Y.; Zhang, Y.; Li, G.; Chen, X.; Zhan, S.; Huang, J.

10.1101/2024.01.08.574671 — ecology — Posted on 2024-01-09

3560 Effectiveness of a network Open House model to recruit trainees to post-baccalaureate STEM programs

Aoki, S. T.; Lewellyn, L.; Justice, S.; Mordan-McCombs, S.; Tewari, N.; Cantu, J.; Seiser, R.; Lakhani, A.; Kowalski, J. R.

10.1101/2024.01.08.574670 — scientific communication and education — Posted on 2024-01-09

3561 Elephants in a teacup: Ranging and Habitat-use of Asian elephants Elephas maximus in a Plantation Dominated Landscape in Southern Western Ghats, India

Vijayakrishnan, S.; Raghunathan, G.; Ananda Kumar, M.; Sinha, A.

10.1101/2024.01.08.574633 — ecology — Posted on 2024-01-09

3562 Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome

Xu, H.; Kong, L.; Cheng, J.; Al Moussawi, K.; Chen, X.; Iqbal, A.; Wing, P. A.; Harris, J. M.; Tsukuda, S.; Embarc-Buh, A.; Wei, G.; Castello, A.; Kriaucionis, S.; McKeating, J.; Lu, X.; Song, C.

10.1101/2024.01.08.574649 — molecular biology — Posted on 2024-01-09

3563 Impaired biogenesis of basic proteins impacts multiple hallmarks of the aging brain

Di Fraia, D.; Marino, A.; Lee, J. H.; Kelmer Sacramento, E.; Baumgart, M.; Bagnoli, S.; Tomaz da Silva, P.; Kumar Sahu, A.; Siano, G.; Tiessen, M.; Gagneur, J.; Frydman, J.; Cellerino, A.; Ori, A.

10.1101/2023.07.20.549210 — systems biology — Posted on 2024-01-09

3564 Patient-Derived Tumor Organoid and Fibroblast Assembloid Models for interrogation of the tumor microenvironment in Esophageal Adenocarcinoma

Sharpe, B. P.; Nazlamova, L. A.; Tse, C.; Johnston, D. A.; Blyth, R.; Pickering, O. J.; Grace, B.; Harrington, J.; Rajak, R.; Rose-Zerilli, M.; Walters, Z. S.; Underwood, T. J.

10.1101/2024.01.02.572565 — cancer biology — Posted on 2024-01-09

3565 NGAL deficiency elicits Hemophilia-like bleeding and clotting disorder

Xue, M.; Wang, S.; Li, C.; Wang, Y.; Liu, M.; Xiao, D.; Yin, Q.; Niu, L.; Shen, C.; Wang, J.; Tang, X.

10.1101/2023.09.15.557008 — biochemistry — Posted on 2024-01-09

3566 Localization of Cadherins in the postnatal cochlear epithelium and their relation to space formation.

Beaulac, H. J.; Munnamalai, V.

10.1101/2023.09.30.560287 — cell biology — Posted on 2024-01-09

3567 Salmonella impairs macrophage immunity through effector-independent rapid translational induction in response to membrane puncture by the SPI-1 injectisome

Wood, G.; Powell, J.; Johnson, R.; Lastovka, F.; Bryant, O.; Brember, M.; Tourlomousis, P.; Carr, J.; Bryant, C.; Chung, B. Y.

10.1101/2023.07.21.550113 — molecular biology — Posted on 2024-01-09

3568 Sustained EEG responses to rapidly unfolding stochastic sounds reflect precision tracking

Zhao, S.; Skerritt-Davis, B.; Elhilali, M.; Dick, F.; Chait, M.

10.1101/2024.01.08.574691 — neuroscience — Posted on 2024-01-09

3569 Task-anchored grid cell firing is selectively associated with successful path integration-dependent behaviour

Clark, H.; Nolan, M. F.

10.1101/2023.05.12.540491 — neuroscience — Posted on 2024-01-09

3570 Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability

Duveau, F. M.; Cordier, C.; Chiron, L.; Le Bec, M.; Pouzet, S.; Seguin, J.; Llamosi, A.; Sorre, B.; Di Meglio, J.-M.; Hersen, P.

10.1101/2023.02.17.528926 — systems biology — Posted on 2024-01-09

3571 Cytoplasmic Viscosity is a Potential Biomarker for Metastatic Breast Cancer Cells

Dessard, M.; Manneville, J.-B.; Berret, J.-F.

10.1101/2023.10.25.564072 — biophysics — Posted on 2024-01-09

3572 The J-Like Protein ARC6 Regulates Chloroplast FtsZ-Ring Assembly through Fine-tuning ARC3 Activity in Arabidopsis

Du, W.; Cao, L.; Zhou, Y.; Jackson, S.; Naeem, M.; Yang, Y.; Glynn, J.; Porter, K.; He, Q.; Xu, J.; Liang, W.; Osteryoung, K. W.; Chen, C.

10.1101/2024.01.08.574726 — plant biology — Posted on 2024-01-08

3573 Effects of Alzheimer's disease plasma marker levels on multilayer centrality in healthy individuals

Garcia-Colomo, A.; Lopez-Sanz, D.; Taguas, I.; Carrasco-Gomez, M.; Spuch, C.; Comis-Tuche, M.; Maestu, F.

10.1101/2024.01.08.573504 — neuroscience — Posted on 2024-01-09

3574 A common regulatory switch controls a suite of C4 traits in multiple cell types

Camo-Escobar, D.; Alcala-Gutierrez, C.; Palafox-Figueroa, E.; Guillotin, B.; Hernandez-Coronado, M.; Coyac-Rodriguez, J. L.; Cerbantez-Bueno, V. E.; Velez-Ramirez, A.; de Folter, S.; Birnbaum, K. D.; Ortiz-Ramirez, C. H.

10.1101/2023.12.21.572850 — plant biology — Posted on 2024-01-09

3575 Mimicking drought transcriptional responses using a high throughput plate assay

Gonzalez, S.; Swift, J.; Yaaran, A.; Xu, J.; Miller, C.; Illouz-Eliaz, N.; Nery, J. R.; Zait, Y.; Busch, W.; Ecker, J. R.

10.1101/2022.11.25.517922 — plant biology — Posted on 2024-01-09

3576 Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2

Sun, F.; Yan, P.; Xiao, Y.; Zhang, H.; Shapiro, S. D.; Xiao, G.; Qu, Z.

10.1101/2023.07.23.550248 — cancer biology — Posted on 2024-01-09

3577 SC-Track: a robust cell tracking algorithm for generating accurate single cell lineages from diverse cell segmentations

Li, C.; Xie, S. S.; Wang, J.; Sharvia, S.; Chan, K. Y.

10.1101/2023.10.03.560639 — bioinformatics — Posted on 2024-01-09

3578 Streamlining the alignment of UAV and TLS forest point clouds: an approach based on ground and tree stems

Puletti, N.; Innocenti, S.; Guasti, M.

10.1101/2024.01.03.574086 — bioinformatics — Posted on 2024-01-09

3579 An association between Dnmt1 and Wnt in the production of oocytes in the 1 whitefly Bemisia tabaci

Cunningham, C.; Shelby, E. A.; McKinney, E. C.; Simmons, A. M.; Moore, A. J.; Moore, P. J.

10.1101/2023.09.13.557185 — genomics — Posted on 2024-01-09

3580 Discovery of NRG1-VII: a novel myeloid-derived class of NRG1 isoforms

Angel Berrocal-Rubio, M.; Prawer, Y. D. J.; Dinevska, M.; De Paoli-Iseppi, R.; Widodo, S. S.; Gleeson, J.; Rajab, N.; De Nardo, W.; Hallab, J. C.; Li, A.; Mantamadiotis, T.; Clark, M.; Wells, C.

10.1101/2023.02.02.525781 — genomics — Posted on 2024-01-09

3581 Comparing methylation levels assayed in GC-rich regions with current and emerging methods

Guanzon, D.; Ross, J. P.; Ma, C.; Berry, O.; Liew, Y. J.

10.1101/2023.09.06.556603 — genomics — Posted on 2024-01-09

3582 Elimination of subtelomeric repeat sequences exerts little effect on telomere functions in Saccharomyces cerevisiae

Hu, C.; Zhu, X.; He, M.-H.; Shao, Y.; Qin, Z.; Wu, Z.; Zhou, J.

10.1101/2023.08.29.555450 — genetics — Posted on 2024-01-09

3583 The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution

Eleftheriadi, K.; Guiglielmoni, N.; Salces-Ortiz, J.; Vargas-Chavez, C.; Martinez-Redondo, G. I.; Gut, M.; Flot, J.-F.; Schmidt-Rhaesa, A.; Fernandez, R.

10.1101/2023.06.26.546503 — evolutionary biology — Posted on 2024-01-09

3584 From solitary to colonial with zooid miniaturization: ancestral-state reconstruction based on NGS data of stolidobranch ascidians

Hasegawa, N.; Kajihara, H.; Matsubara, S.; Shenkar, N.

10.1101/2023.12.27.573391 — evolutionary biology — Posted on 2024-01-09

3585 Early survival in Atlantic salmon is associated with parental genotypes at loci linked to timing of maturation late in life

Aykanat, T.; McLennan, D.; Metcalfe, N. B.; Prokkola, J. M.

10.1101/2024.01.08.574625 — evolutionary biology — Posted on 2024-01-09

3586 The larva and adult of Helicoverpa armigera use differential gustatory receptors to sense sugars

Zhang, S.-S.; Wang, P.-C.; Ning, C.; Yang, K.; Li, G.-C.; Cao, L.-L.; Huang, L.-Q.; Wang, C.-Z.

10.1101/2023.09.19.558417 — ecology — Posted on 2024-01-09

3587 A distinct subpopulation of adipocytes in adult perirenal adipose tissue arises through brown-to-white conversion but reverts to a thermogenic phenotype upon cold exposure

Zhang, H.; Li, Y.; Ibanez, C. F.; Xie, M.

10.1101/2023.10.11.561821 — developmental biology — Posted on 2024-01-09

3588 Graft of cardiac progenitors in a pig model of right ventricular failure triggers myocardial epimorphosis, regeneration and protection of function

LAMBERT, V.; DELERIS, A.; TIBOURTINE, F.; FOUILLOUX, V.; MARTIN, A.; BRIDGE, P.; ARIES, E.; BENOIST, D.; PUCEAT, M.

10.1101/2022.07.04.498652 — developmental biology — Posted on 2024-01-09

3589 Unveiling genome plasticity and a novel phage in Mycoplasma felis: Genomic investigations of four feline isolates

Klose, S. M.; Legione, A. R.; Bushell, R. N.; Browning, G. F.; Vaz, P. K.

10.1101/2023.12.16.572022 — microbiology — Posted on 2024-01-09

3590 Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease

10.1101/2024.01.07.574561 — immunology — Posted on 2024-01-09

3591 Thermal cycling-hyperthermia down-regulates liposaccharide-induced inflammation in human blood and helps with clearance of herpes simplex virus type 1

Kuo, Y.-Y.; Lin, G.-B.; Chen, W.-T.; Chen, Y.-M.; Liu, H.-H.; Chao, C.-Y.

10.1101/2022.12.20.521318 — immunology — Posted on 2024-01-09

3592 A high-density diffuse optical tomography dataset of naturalistic viewing

Sherafati, A.; Bajracharya, A.; Jones, M.; Speh, E.; Munsi, M.; Lin, C.-H. P.; Fishell, A. K.; Hershey, T.; Eggebrecht, A. T.; Culver, J. P.; Peelle, J. E.

10.1101/2023.11.07.565473 — neuroscience — Posted on 2024-01-09

3593 Evolution of cell-type-specific accessible chromatin regions and the cis-regulatory elements that drive lineage-specific innovation

Yan, H.; Mendieta, J. P.; Zhang, X.; Marand, A. P.; Liang, Y.; Luo, Z.; Roule, T.; Wagner, D.; Tu, X.; Wang, Y.; Zhong, S.; Wessler, S. R.; Schmitz, R. J.

10.1101/2024.01.08.574753 — plant biology — Posted on 2024-01-09

3594 Uncovering Minimal Pathways in Melanoma Initiation

Xiao, H.; Shiu, J.; Chen, C.-F.; Wu, J.; Zhou, P.; Telang, S. S.; Ruiz-Vega, R.; Lander, A. D.; Ganesan, A. K.

10.1101/2023.12.08.570336 — cancer biology — Posted on 2024-01-09

3595 Sequence clustering confounds AlphaFold2

Schafer, J. W.; Chakravarty, D.; Chen, E. A.; Porter, L. L.

10.1101/2024.01.05.574434 — bioinformatics — Posted on 2024-01-09

3596 Environmental legacy effects impact maize growth and microbiome assembly under drought stress

Swift, J. F.; Kolp, M. R.; Carmichael, A.; Ford, N. E.; Hansen, P. M.; Sikes, B. A.; Kleiner, M.; Wagner, M. R.

10.1101/2023.04.11.536405 — plant biology — Posted on 2024-01-08

3597 Arabidopsis and Maize Terminator Strength is Determined by GC Content, Polyadenylation Motifs and Cleavage Probability

Gorjifard, S.; Jores, T.; Tonnies, J.; Mueth, N. A.; Bubb, K. L.; Wrightsman, T.; Buckler, E. S.; Fields, S.; Cuperus, J. T.; Queitsch, C.

10.1101/2023.06.16.545379 — plant biology — Posted on 2024-01-08

3598 Regulation of the aurantio-obtusin accumulation by StTCP4.1-mediated StDA1-StHDR1 module in Senna tora seeds

Liu, S.; Liu, J.; Abozeid, A.; Ying, X.; Dong, J.; Liang, Z.-s.

10.1101/2024.01.08.574662 — molecular biology — Posted on 2024-01-08

3599 A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

Puray-Chavez, M.; LaPak, K.; Jasuja, R.; Pan, J.; Xu, J.; Eschbach, J. E.; Mohammed, S.; Lawson, D.; Wang, Q.; Brody, S. L.; Major, M. B.; Goldfarb, D.; Kutluay, S. B.

10.1101/2024.01.07.574522 — microbiology — Posted on 2024-01-08

3600 MotorNet: a Python toolbox for controlling differentiable biomechanical effectors with artificial neural networks

Codol, O.; Michaels, J. A.; Kashefi, M.; Pruszynski, J. A.; Gribble, P. L.

10.1101/2023.02.17.528969 — neuroscience — Posted on 2024-01-08

3601 Pelage Variation and Morphometrics of Closely Related Callithrix Marmoset Species and Their Hybrids

Malukiewicz, J.; Warren, K.; Boere, V.; Bandeira, I. L.; Curi, N. H.; das Dores, F. T.; Fitorra, L. S.; Furuya, H. R.; Igayara, C. S.; Milanelo, L.; Moreira, S. B.; Molina, C. V.; Nardi, M. S.; Nicola, P. A.; Passamani, M.; Pedro, V. S.; Pereira, L. C.; Petri, B.; Pissinatti, A.; Quirino, A. A.; Rogers, J.; Ruiz-Miranda, C. R.; Silva, D. L.; Silva, I. O.; Silva, M. O.; Suma, J. L.; Zwarg, T.; Ackermann, R. R.

10.1101/2023.01.01.522211 — zoology — Posted on 2024-01-08

3602 Early survival in Atlantic salmon is associated with parental genotype at loci linked to timing of maturation late in life

Aykanat, T.; McLennan, D.; Metcalfe, N. B.; Prokkola, J. M.

10.1101/2024.01.08.574625 — evolutionary biology — Posted on 2024-01-08

3603 Consumption of only wild foods induces large-scale, partially-persistent alterations to the gut microbiome

Rampelli, S.; Pomstra, D.; Barone, M.; Fabbrini, M.; Turroni, S.; Candela, M.; Henry, A. G.

10.1101/2024.01.08.574648 — microbiology — Posted on 2024-01-08

3604 The value of livestock abortion surveillance in Tanzania: identifying disease priorities and informing interventions

Lankester, F.; Kibona, T. J.; Allan, K. J.; de Glanville, W.; Buza, J. J.; Katzer, F.; Halliday, J. E.; Mmbaga, B. T.; Wheelhouse, N.; Innes, E. A.; Thomas, K.; Nyasebwa, O. M.; Swai, E.; Claxton, J. R.; Cleaveland, S.

10.1101/2024.01.07.574517 — zoology — Posted on 2024-01-08

3605 Identification of candidate genes controlling red seed coat color in cowpea (Vigna unguiculata Walp)

Herniter, I. A.; Munoz-Amatriain, M.; Lo, S.; Guo, Y.-N.; Lonardi, S.; Close, T. J.

10.1101/2024.01.08.574663 — plant biology — Posted on 2024-01-08

3606 The Cancer Testis Antigen Testis Specific Serine Kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and is essential for oncogenic behaviors

Delgado, M.; McGlynn, K.; Stippec, S.; Cobb, M. H.; Whitehurst, A.

10.1101/2024.01.08.574658 — cancer biology — Posted on 2024-01-08

3607 Imaging the structural connectome with hybrid diffusion MRI-microscopy tractography

Zhu, S.; Huszar, I. N.; Cottaar, M.; Daubney, G.; Eichert, N.; Hanayik, T.; Khrapitchev, A. A.; Mars, R. B.; Mollink, J.; Sallet, J.; Scott, C.; Smart, A.; Jbabdi, S.; Miller, K. L.; Howard, A. F.

10.1101/2024.01.08.574641 — bioengineering — Posted on 2024-01-08

3608 Using FINDeM for rapid, CRISPR-based detection of the emerging salamandrid fungal pathogen, Batrachochytrium salamandrivorans.

Hoenig, B. D.; Boning, P.; Plewnia, A.; Richards-Zawacki, C. L.

10.1101/2024.01.08.573879 — ecology — Posted on 2024-01-08

3609 Imaging Giardia intestinalis cellular organisation using expansion microscopy revealed atypical centrin localisation.

Soukup, J.; Zelena, M.; Weisz, F.; Kostelanska, M.; Nohynkova, E.; Tumova, P.

10.1101/2024.01.08.574661 — microbiology — Posted on 2024-01-08

3610 Organ Boundary Circuits Regulate Sox9+ Alveolar Tuft Cells During Post-Pneumonectomy Lung Regeneration

Obata, T.; Mizoguchi, S.; Greaney, A. M.; Adams, T. S.; Yuan, Y.; Edelstein, S.; Leiby, K. L.; Rivero, R.; Wang, N.; Kim, H.; Yang, J.; Schupp, J. C.; Stitelman, D.; Tsuchiya, T.; Levchenko, A.; Kaminski, N.; Niklason, L. E.; Raredon, M. S. B.

10.1101/2024.01.07.574469 — systems biology — Posted on 2024-01-08

3611 Prediction of representative phenotypes using Multi-Attribute Subset Selection

Herbst, K.; Wang, T.; Forchielli, E.; Thommes, M.; Paschalidis, I. C.; Segre, D.

10.1101/2022.06.20.496733 — systems biology — Posted on 2024-01-08

3612 Designing host-associated microbiomes using the consumer/resource model

Plata, G. D.; Krishnamurthy, M.; Herron, L.; Dixit, P.

10.1101/2023.04.28.538625 — systems biology — Posted on 2024-01-08

3613 Circadian and environmental signal integration in a natural population of Arabidopsis

Nishio, H.; Cano-Ramirez, D. L.; Muranaka, T.; de Barros Dantas, L. L.; Honjo, M. N.; Sugisaka, J.; Kudoh, H.; Dodd, A.

10.1101/2022.09.10.507414 — plant biology — Posted on 2024-01-08

3614 Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren's disease

Son, G.-Y.; Zou, A.; Wahl, A.; Huang, K. T.; Vinu, M.; Zorgit, S.; Zhou, F.; Wagner, L.; Idaghdour, Y.; Yule, D. I.; Feske, S.; Lacruz, R. S.

10.1101/2024.01.08.574702 — physiology — Posted on 2024-01-08

3615 Impact of Capillary and Sarcolemmal Proximity on Mitochondrial Structure and Energetic Function in Skeletal Muscle

Parry, H. A.; Willingham, T. B.; Giordano, K. A.; Kim, Y.; Qazi, S.; Knutson, J. R.; Combs, C. A.; Glancy, B.

10.1101/2024.01.08.574684 — physiology — Posted on 2024-01-08

3616 E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

Patterson, M. R.; Meijers, A. S.; Ryder, E. L.; Scarth, J. A.; Evans, D.; Turner, A. L.; Wasson, C. W.; Daryl, J. E.; James, C. D.; Wang, M.; Ladbury, J. E.; Morgan, I. M.; Samson, A.; Morgan, E. L.; Macdonald, A.

10.1101/2024.01.08.574687 — cancer biology — Posted on 2024-01-08

3617 Lipid osmosis, membrane tension, and other mechanochemical driving forces of lipid flow

Zhang, Y.; Lin, C.

10.1101/2024.01.08.574656 — biophysics — Posted on 2024-01-08

3618 Machine Learning-based Classification of transcriptome Signatures of non-ulcerative Bladder Pain Syndrome

Akshay, A.; Besic, M.; Kuhn, A.; Burkhard, F. C.; Bigger-Allen, A. A.; Adam, R.; Monastyrskaya, K.; Hashemi Gheinani, A.

10.1101/2024.01.08.574189 — bioinformatics — Posted on 2024-01-08

3619 Towards Real-Time Airborne Pathogen Sensing: Electrostatic Capture and On-Chip LAMP Based Detection of Airborne Viral Pathogens

Jaykumar, N. S.; Caffrey, V.; Paprotny, I.; Caffrey, M.

10.1101/2024.01.05.574431 — bioengineering — Posted on 2024-01-08

3620 Deuteration of proteins boosted by cell lysates: high-resolution amide and Hα MAS NMR without re-protonation bottleneck

Napoli, F.; Guan, J.-Y.; Arnaud, C.-A.; Macek, P.; Fraga, H.; Breyton, C.; Schanda, P.

10.1101/2024.01.08.574509 — biochemistry — Posted on 2024-01-08

3621 Target-aware Molecule Generation for Drug Design Using a Chemical Language Model

10.1101/2024.01.08.574635 — biochemistry — Posted on 2024-01-08

3622 Network studies unveil new groups of highly divergent proteins in families as old as cellular life with important biological functions in the ocean

Sussfeld, D.; Lannes, R.; Corel, E.; Bernard, G.; Martin, P.; Bapteste, E.; Pelletier, E.; Lopez, P.

10.1101/2024.01.08.574615 — evolutionary biology — Posted on 2024-01-08

3623 BLADE-ON-PETIOLE interacts with CYCLOIDEA to fine-tune CYCLOIDEA-mediated flower symmetry in Monkeyflowers (Mimulus)

Gao, Y.; Li, J.; He, J.; Yu, Y.; Qian, Z.; Geng, Z.; Yang, L.; Zhang, Y.; Ke, Y.; Lin, Q.; Wang, J.; Chen, S.; Chen, F.; Yuan, Y.-W.; Ding, B.

10.1101/2024.01.08.574647 — developmental biology — Posted on 2024-01-08

3624 A distinct signalling circuit upregulates cytotoxic ROS production in a cellular model of Parkinsons disease: key roles for TRPM2, Zn2+ and complex III

AlAhmad, M.; Isbea, H.; Shitaw, E.; Li, F.; Sivaprasadarao, A.

10.1101/2024.01.08.574664 — cell biology — Posted on 2024-01-08

3625 GENOMIC PROFILING OF SARS-COV-2 STRAINS CIRCULATING IN SOUTH EASTERN REGION OF INDIA DURING THREE WAVES OF PANDEMIC

Kandhasamy, V.; Balakrishna Pillai, A.; Mariappan, V.; Ramalingam, M.; Raganadin, P.; Ramadoss, R.; Moovarkumudalvan, B.; Easow, J. M.; Vasudevan, M.; S.R., R.

10.1101/2024.01.06.574128 — molecular biology — Posted on 2024-01-08

3626 Pear flower and leaf microbiome dynamics during the naturally occurring spread of Erwinia amylovora

Oz, A.; Mairesse, O.; Raikin, S.; Hanani, H.; Dafny Yelin, M.; Sharon, I.

10.1101/2024.01.08.574646 — microbiology — Posted on 2024-01-08

3627 Phago-mixotrophy of small eukaryotic phytoplankton might alleviate iron limitation in HNLC Southern Ocean

Ong, D. R. Y.; Gutierrez-Rodriguez, A.; Safi, K. A.; Marie, D.; Selph, K. E.; Stukel, M. R.; Decima, M.; Lopes dos Santos, A.

10.1101/2024.01.08.574519 — microbiology — Posted on 2024-01-08

3628 Unraveling wheat endosperm development: epigenetic regulation and novel regulators for enhanced yield and quality

Zhao, L.; Chen, J.; Zhang, Z.; Wu, W.; Lin, X.; Gao, M.; Yang, Y.; Zhao, P.; Yao, Y.; Zhang, A.; Liu, D.; Wang, D.; Xiao, J.

10.1101/2024.01.08.574643 — plant biology — Posted on 2024-01-08

3629 Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19

Ashok, D.; Liu, T.; Criscione, J.; Prakash, M.; Kim, B.; Chow, J.; Craney, M.; Papanicolaou, K.; Sidor, A.; Foster, D. B.; Pekosz, A.; Villano, J.; Kim, D.-H.; O'Rourke, B.

10.1101/2024.01.05.574280 — pathology — Posted on 2024-01-08

3630 Cell type specific long non-coding RNA targets identified by integrative analysis of single-cell and bulk colorectal cancer transcriptomes

Mihaljevic, A.; Rubin, P.; Chouvardas, P.; Esposito, R.

10.1101/2024.01.08.574618 — cancer biology — Posted on 2024-01-08

3631 Glioblastoma cells imitate neuronal excitability in humans

Tong, T.; Ozsvar, A.; Eschen, J. T.; Elbaek, K. J.; Cortnum, S. O. S.; Sindby, A. K.; Kristensen, B. W.; Meier, K.; Mikic, N.; Sorensen, J. C. H.; Ting, J. T.; Capogna, M.; Hou, W.-H.; Korshoj, A. R.

10.1101/2024.01.08.574637 — cancer biology — Posted on 2024-01-08

3632 The kinetics of SARS-CoV-2 nsp7-11 polyprotein processing and impact on complexation with nsp16

Schamoni-Kast, K.; Krichel, B.; Damjanovic, T.; Kierspel, T.; Toker, S.; Uetrecht, C.

10.1101/2024.01.06.574466 — biophysics — Posted on 2024-01-08

3633 DNA methylation enables recurrent endogenization of giant viruses in an animal relative

Sarre, L. A.; Kim, I. V.; Ovchinnikov, V.; Olivetta, M.; Suga, H.; Dudin, O.; Sebe-Pedros, A.; de Mendoza, A.

10.1101/2024.01.08.574619 — evolutionary biology — Posted on 2024-01-08

3634 A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development

Courtney, Y.; Head, J. P.; Yimer, E. D.; Dani, N.; Shipley, F. B.; Libermann, T. A.; Lehtinen, M. K.

10.1101/2024.01.08.574486 — neuroscience — Posted on 2024-01-08

3635 Long days induce adaptive secondary dormancy in seed of the Mediterranean plant Aethionema arabicum

Merai, Z.; Graeber, K.; Xu, F.; Dona, M.; Lalatovic, K.; Wilhelmsson, P. K. I.; Fernandez-Pozo, N.; Rensing, S. A.; Leubner-Metzger, G.; Mittelsten Scheid, O.; Dolan, L.

10.1101/2024.01.08.574645 — plant biology — Posted on 2024-01-08

3636 A Functional Analysis of a Resorbable Citrate-based Composite Tendon Anchor

Thirumaran, A.; Poudel, A.; Sankar, M.; Doulgkeroglou, M.; Easley, J.; Gadomski, B.; Biggs, M.

10.1101/2024.01.08.571095 — bioengineering — Posted on 2024-01-08

3637 Engineering of methionine-auxotroph Escherichia coli via parallel evolution of two enzymes from Corynebacterium glutamicum's direct-sulfurylation pathway enables its recovery in minimal medium

Gabay, M.; Stern, I.; Gruzdev, N.; Cohen, A.; Lifshits, L. A.; Ansbacher, T.; Yadid, I.; Gal, M.

10.1101/2024.01.08.574620 — biochemistry — Posted on 2024-01-08

3638 A new story of four Hexapoda classes: Protura as the sister to all other hexapods

Du, S.; Tihelka, E.; Yu, D.; Chen, W.-J.; Bu, Y.; Cai, C.; Engel, M. S.; Luan, Y.-X.; Zhang, F.

10.1101/2024.01.08.574592 — evolutionary biology — Posted on 2024-01-08

3639 SRCompiler: Translating Stella dynamic models to open-source R scripts

Morales-Castello, E.; Bordehore, C.; Pastor, H. M.; Garcia-Garcia, D.

10.1101/2024.01.08.574614 — ecology — Posted on 2024-01-08

3640 Large-scale computational analyses of gut microbial CAZyme repertoires enabled by Cayman

Ducarmon, Q. R.; Karcher, N.; Tytgat, H. L. P.; Delannoy-Bruno, O.; Pekel, S.; Springer, F.; Schudoma, C.; Zeller, G.

10.1101/2024.01.08.574624 — microbiology — Posted on 2024-01-08

3641 MAIT cells protect against sterile lung injury

Zhang, X.; Li, S.; Lason, W.; Greco, M.; Klenerman, P.; Hinks, T. S. C.

10.1101/2024.01.08.574631 — immunology — Posted on 2024-01-08

3642 Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling

Yuk, C. M.; Kim, D.; Hong, S.; Kim, M.; Jeong, H.-W.; Park, S. J.; Min, H.; Kim, W.; Kim, S.-G.; Seong, R. H.; Kim, S.; Lee, S.-H.

10.1101/2024.01.08.574595 — immunology — Posted on 2024-01-08

3643 Aberrant Connectivity Across the Lifespan in a Mouse Model of Alzheimer's disease and Rescue by mGluR5 Modulator Treatment

Mandino, F.; Shen, X.; Desrosiers-Gregoire, G.; O'Connor, D.; Mukherjee, B.; Owens, A.; Qu, A.; Onofrey, J.; Papademetris, X.; Chakravarty, M.; Strittmatter, S. M.; Lake, E. M.

10.1101/2023.12.15.571715 — neuroscience — Posted on 2024-01-08

3644 Arm movements increase acoustic markers of expiratory flow

Werner, R.; Selen, L.; Pouw, W.

10.1101/2024.01.08.574611 — neuroscience — Posted on 2024-01-08

3645 Pathways controlling neurotoxicity and proteostasis in mitochondrial complex I deficiency

Nithianadam, V.; Sarkar, S.; Feany, M. B.

10.1101/2024.01.08.574634 — neuroscience — Posted on 2024-01-08

3646 Dynamic evolution of the heterochromatin sensing histone demethylase IBM1

Zhang, Y.; Jang, H.; Luo, Z.; Schmitz, R. J.

10.1101/2024.01.08.574644 — plant biology — Posted on 2024-01-08

3647 Rheological transition driven by matrix makes cancer spheroids resilient under confinement

Dutt, T.; Langthasa, J.; U, M.; Mishra, S.; Bothra, S.; Vadaparty, A.; Sen, P.; Bhat, R.

10.1101/2022.02.09.479678 — biophysics — Posted on 2024-01-08

3648 CONSULT-II: Accurate taxonomic identification and profiling using locality-sensitive hashing

Sapci, A. O. B.; Rachtman, E.; Mirarab, S.

10.1101/2023.11.07.566115 — bioinformatics — Posted on 2024-01-08

3649 Unraveling the genetic legacy of commercial whaling in bowhead whales and narwhals

de Greef, E.; Müller, C.; Thorstensen, M. J.; Ferguson, S. H.; Watt, C. A.; Marcoux, M.; Petersen, S. D.; Garroway, C. J.

10.1101/2024.01.04.574243 — genomics — Posted on 2024-01-08

3650 Genome biology and evolution of mating type loci in four cereal rust fungi

Luo, Z.; McTaggart, A. R.; Schwessinger, B.

10.1101/2023.03.02.530769 — evolutionary biology — Posted on 2024-01-08

3651 Movements and habitat selection of a marsupial carnivore in a modified landscape

Jones, E. M.; Koch, A. J.; Pay, J. M.; Mann, D. F.; Jones, M. E.; Hamede, R. K.

10.1101/2023.03.05.531208 — ecology — Posted on 2024-01-08

3652 Transoceanic pathogen circulation in the age of sail and steam

Blackmore, E. N.; Lloyd-Smith, J. O.

10.1101/2024.01.01.573813 — ecology — Posted on 2024-01-08

3653 Graft of cardiac progenitors in a pig model of right ventricular failure triggers myocardial epimorphosis, regeneration and protection of function

LAMBERT, V.; DELERIS, A.; TIBOURTINE, F.; FOUILLOUX, V.; MARTIN, A.; BRIDGE, P.; ARIES, E.; BENOIST, D.; PUCEAT, M.

10.1101/2022.07.04.498652 — developmental biology — Posted on 2024-01-08

3654 Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during behavior and learning

Heer, C. M.; Sheffield, M. E. J.

10.1101/2023.11.29.569214 — neuroscience — Posted on 2024-01-08

3655 Maturation and conformational switching of a de novo designed phase-separating polypeptide

Hilditch, A. T.; Romanyuk, A.; Hodgson, L. R.; Mantell, J.; Neal, C. R.; Verkade, P.; Obexer, R.; Serpell, L. C.; McManus, J. J.; Woolfson, D. N.

10.1101/2024.01.08.574599 — synthetic biology — Posted on 2024-01-08

3656 ANDROMEDA by Prosilico and log D outperform human hepatocytes for the prediction of intrinsic hepatic metabolic clearance of carboxylic acids

Fagerholm, U.

10.1101/2023.12.04.569912 — pharmacology and toxicology — Posted on 2024-01-08

3657 A Practical Approach for Targeting Structural Variants Genome-wide in Plasma Cell-free DNA

Murata, M. M.; Igari, F.; Urbanowicz, R.; Mouakkad, L.; Kim, S.; Chen, Z.; Di Vizio, D.; Posadas, E. M.; Giuliano, A. E.; Tanaka, H.

10.1101/2023.10.25.564058 — cancer biology — Posted on 2024-01-08

3658 Bridging biodiversity and gardening: Unravelling the interplay of socio-demographic factors, garden practices, and garden characteristics

Varga-Szilay, Z.; Fetyko, K. G.; Szovenyi, G.; Pozsgai, G.

10.1101/2023.12.03.569783 — ecology — Posted on 2024-01-08

3659 Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon

Sharma, N.; Qi, X.; Kessler, P.; Sen, G. C.

10.1101/2024.01.08.574713 — cell biology — Posted on 2024-01-08

3660 Epsins promote atherosclerosis through VSMC phenotypic modulation

Wang, B.; Cui, K.; Zhu, B.; Dong, Y.; Wang, D.; Singh, B.; Lu, Y. W.; Wu, H.; Bhattacharjee, S.; Eisa-Beygi, S.; Wong, S.; Cowan, D. B.; Du, M.; Chen, H.

10.1101/2024.01.08.574714 — cell biology — Posted on 2024-01-08

3661 Systemic Dosing of Virus-derived Serpin Improves Survival and Immunothrombotic Damage in Murine Colitis

Zhang, L.; Turk, J. R.; Monder, H.; Woodrow, C. R.; Spaccarelli, L.; Garg, A.; Schlievert, J.; Elmadbouly, N.; Dupati, A.; Kilbourne, J.; Lowe, K. M.; Aliskevich, E.; Satyanarayanan, R. S.; Saju, R.; Hamada, M.; Pinteric, A.; Zanetti, I. R.; Enow, J.; Florsheim, E. B.; Rahman, M.; Irving, J. A.; McFadden, G.; Kong, W.; Lucas, A. R.

10.1101/2024.01.08.574715 — molecular biology — Posted on 2024-01-08

3662 EEG responses to rapidly unfolding stochastic sounds reflect precision tracking

Zhao, S.; Skirritt-Davis, B.; Elhilali, M.; Dick, F.; Chait, M.

10.1101/2024.01.08.574691 — neuroscience — Posted on 2024-01-08

3663 Kinematic and neuromuscular characterization of cognitive involvement in gait control in healthy young adults

LANA, V.; FRERE, J.; CABIBEL, V.; REGUEME, T.; LEFEVRE, N.; Vlamynck, E.; DECKER, L. M.

10.1101/2022.07.01.498421 — neuroscience — Posted on 2024-01-08

3664 A new look at the architecture and dynamics of the Hydra nerve net

Keramidioti, A.; Schneid, S.; Busse, C.; Cramer von Laue, C.; Bertulat, B.; Salvenmoser, W.; Hess, M.; Alexandrova, O.; Glauber, K.; Steele, R.; Hobmayer, B.; Holstein, T. W.; David, C. N.

10.1101/2023.02.22.529525 — neuroscience — Posted on 2024-01-08

3665 Mesophyll-Specific Circadian Dynamics of CAM Induction in the Ice Plant Unveiled by Single-Cell Transcriptomics

Perron, N.; Dervinis, C.; Pereira, W. J.; Barbazuk, W. B.; Kirst, M.

10.1101/2024.01.05.574430 — plant biology — Posted on 2024-01-08

3666 Direct excitatory synapses between neurons and tumor cells drive brain metastatic seeding of breast cancer and melanoma

Venkataramani, V.; Karreman, M. A.; Nguyen, L. C.; Tehranian, C.; Hebach, N.; Mayer, C.; Meyer, L.; Mughal, S.; Reifenberger, G.; Felsberg, J.; Koehrer, K.; Schubert, M. C.; Westphal, D.; Breckwolt, M.; Brors, B.; Wick, W.; Kuner, T.; Winkler, F.

10.1101/2024.01.08.574608 — cancer biology — Posted on 2024-01-08

3667 Kinetic stabilization of translation-repression condensates by a neuron-specific microexon

Garcia-Cabau, C.; Bartomeu, A.; Tesei, G.; Cheung, K. C.; Pose-Utrilla, J.; Pico, S.; Balaceanu, A.; Duran-Arque, B.; Fernandez-Alfara, M.; Martin, J.; De Pace, C.; Ruiz-Perez, L.; Garcia, J.; Battaglia, G.; Lucas, J. J.; Hervas, R.; Lindorff-Larsen, K.; Mendez, R.; Salvatella, X.

10.1101/2023.03.19.532587 — biophysics — Posted on 2024-01-08

3668 Cell-Specific Gene Networks and Drivers in RheumatoidArthritis Synovial Tissues

Pelissier, A.; Laragione, T.; Gulko, P. S.; Martinez, M. R.

10.1101/2023.12.28.573505 — bioinformatics — Posted on 2024-01-08

3669 The defensome of complex bacterial communities

Beavogui, A.; Lacroix, A.; Wiart, N.; Poulain, J.; Delmont, T. O.; Paoli, L.; Wincker, P.; Oliveira, P. H.

10.1101/2023.08.12.553040 — genomics — Posted on 2024-01-08

3670 Deciphering the genetic interactions between Pou4f3, Gfi1 and Rbm24 in maintaining cochlear hair cell survival

Wang, G.; Gu, Y.; Liu, Z.

10.1101/2023.06.22.546097 — developmental biology — Posted on 2024-01-08

3671 K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific interactors.

Waltho, A.; Popp, O.; Lenz, C.; Pluska, L.; Dötsch, V.; Mertins, P.; Sommer, T.

10.1101/2024.01.08.574586 — molecular biology — Posted on 2024-01-08

3672 CD177 is a novel IgG Fc receptor and CD177 genetic variants affect IgG-mediated function

Li, Y.; Wu, J.

10.1101/2024.01.07.574546 — immunology — Posted on 2024-01-08

3673 An adaptable, reusable, and light implant for chronic Neuropixels probes

Bimbard, C.; Takacs, F.; Catarino, J. A.; Fabre, J. M.; Gupta, S.; Lenzi, S. C.; Melin, M. D.; O'Neill, N.; Robacha, M.; Street, J. S.; Teixeira, J.; Townsend, S.; van Beest, E. H.; Zhang, A. M.; Churchland, A. K.; Harris, K. D.; Kullmann, D. M.; Lignani, G.; Mainen, Z. F.; Margrie, T. W.; Rochefort, N. L.; Wikenheiser, A. M.; Carandini, M.; Coen, P.

10.1101/2023.08.03.551752 — neuroscience — Posted on 2024-01-08

3674 Hippocampome.org v2.0: a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits

Wheeler, D. W.; Kopsick, J. D.; Sutton, N.; Tecuatl, C.; Komendantov, A. O.; Nadella, K.; Ascoli, G. A.

10.1101/2023.05.12.540597 — neuroscience — Posted on 2024-01-08

3675 Maize (Zea mays L.) interaction with the arbuscular mycorrhizal fungus Rhizophagus irregularis allows mitigation of nitrogen deficiency stress: physiological and molecular characterization

Decouard, B.; Chowdhury, N. B.; Saou, A.; Rigault, M.; Quillere, I.; Sapir, T.; Marmagne, A.; Paysant le Roux, C.; Launay-Avon, A.; Guerard, F.; Gakiere, B.; Mauve, C.; Levy-Leduc, C.; Barbillon, P.; Saha, R.; Courty, P.-E.; Wipf, D.; Hirel, B.; DELLAGI, A.

10.1101/2023.10.13.562190 — plant biology — Posted on 2024-01-08

3676 Gene Network Analyses Identify Co-regulated Transcription Factors and BACH1 as a Key Driver in Rheumatoid Arthritis Fibroblast-like Synoviocytes

Pelissier, A.; Laragione, T.; Harris, C.; Martinez, M. R.; Gulko, P. S.

10.1101/2023.12.28.573506 — bioinformatics — Posted on 2024-01-08

3677 Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway

Frasca, A.; Miramondi, F.; Butti, E.; Indrigo, M.; Balbontin, M.; Postogna, F. M.; Piffer, A.; Bedogni, F.; Pizzamiglio, L.; Cambria, C.; Borello, U.; Antonucci, F.; Martino, G.; Landsberger, N.

10.1101/2024.01.07.574507 — neuroscience — Posted on 2024-01-08

3678 IN VITRO 5-LOX INHIBITORY POTENTIAL AND ANTIOXIDANT ACTIVITY OF NEW ISOXAZOLE DERIVATIVES

Alam, W.; Khan, H.; Jan, M. S.; Daglia, M.

10.1101/2024.01.08.574589 — pharmacology and toxicology — Posted on 2024-01-08

3679 Binucleated cell formation and oncogene expression after particulate matter exposure is preceded by microtubule disruption, dysregulated cell cycle, prolonged mitosis, and septin binding

Podlipec, R.; Sebastijanovic, A.; Cassidy, H.; Han, L.; Danielsen, P.; Cotar, P.; Kokot, H.; Korosevic Koser, B.; Vencelj, A.; Pirker, L.; Umek, P.; Hlawacek, G.; Heller, R.; Matallanas, D.; Pelicon, P.; Stoeger, T.; Urbancic, I.; Vogel, U.; Koklic, T.; Strancar, J.

10.1101/2024.01.07.574515 — cancer biology — Posted on 2024-01-08

3680 Endoplasmic reticulum stress signaling actively contributes to therapy resistance in colorectal cancer

Sasaki, D.; Sato, N.; Wilhelm, D.; Fischer, J.; Gissibl, J.; Nakatsuji, M.; Haller, D.; Ishihara, H.; Janssen, K.-P.

10.1101/2024.01.07.574523 — cancer biology — Posted on 2024-01-08

3681 Reprogramming neuroblastoma by diet-enhanced polyamine depletion

Cherkaoui, S.; Yang, L.; McBride, M. J.; Turn, C.; Lu, W.; Eigenmann, C.; Allen, G. E.; Panasenko, O. O.; Zhang, L.; Vu, A.; Liu, K.; Li, Y.; Gandhi, O. H.; Surrey, L.; Wierer, M.; White, E.; Rabinowitz, J. D.; Hogarty, M. D.; Morscher, R. J.

10.1101/2024.01.07.573662 — cancer biology — Posted on 2024-01-08

3682 Multiplex Imaging Reveals Novel Subcellular, Microenvironmental, and Racial Patterns of MRTFA/B Activation in Invasive Breast Cancers and Metastases

Wilk, S. M.; Lee, K.; Gajda, A. M.; Haloul, M.; Macias, V.; Wiley, E. L.; Chen, Z.; Liu, X.; Wang, X.; Sverdlov, M.; Hoskins, K. F.; Er, E. E.

10.1101/2024.01.03.573909 — cancer biology — Posted on 2024-01-08

3683 Allostery at a protein-protein interface harboring an intermolecular dynamic network

Medina Gomez, S.; Vasa, S. K.; Linser, R.

10.1101/2024.01.07.574534 — biophysics — Posted on 2024-01-08

3684 Structural dynamics of the methyl-coenzyme M reductase active site are influenced by coenzyme F430 modifications

Poleto, M. D.; Allen, K. D.; Lemkul, J. A.

10.1101/2024.01.07.574536 — biophysics — Posted on 2024-01-08

3685 TrustAffinity: accurate, reliable and scalable out-of-distribution protein-ligand binding affinity prediction using trustworthy deep learning

Badkul, A.; Xie, L.; Zhang, S.; Xie, L.

10.1101/2024.01.05.574359 — bioinformatics — Posted on 2024-01-08

3686 A Supervised Contrastive Framework for Learning Disentangled Representations of Cell Perturbation Data

Tu, X.; Hutter, J.-C.; Wang, Z. J.; Kudo, T.; Regev, A.; Lopez, R.

10.1101/2024.01.05.574421 — bioinformatics — Posted on 2024-01-08

3687 Multiple DNA repair pathways prevent acetaldehyde-induced mutagenesis in yeast

Porcher, L.; Vijayraghavan, S.; McCollum, J.; Mieczkowski, P. A.; Saini, N.

10.1101/2024.01.07.574575 — genetics — Posted on 2024-01-08

3688 A Dimerization-dependent Allosteric Activation for Receptor-like Kinase in Plants

Chen, J.; Cai, D.; Zhang, Y.; Chen, L.; Yu, F.

10.1101/2024.01.06.574453 — plant biology — Posted on 2024-01-08

3689 Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics

Wang, J.; Seo, J. W.; Kare, A. J.; Schneider, M.; Tumbale, S. K.; Wu, B.; Raie, M. N.; Pandrala, M.; Iagaru, A.; Brunsing, R. L.; Charville, G. W.; Park, W. G.; Ferrara, K. W.

10.1101/2024.01.07.574209 — bioengineering — Posted on 2024-01-08

3690 Bioinformatic analysis of sulfotransferases from an unexplored gut microbe, Sutterella wadsworthensis 3_1_45B: Possible roles towards detoxification via sulfation by the members of the human gut microbiome

Langford, L.; Shah, D. D.

10.1101/2024.01.08.574607 — biochemistry — Posted on 2024-01-08

3691 Extant cartilaginous fishes share trabecular and areolar mineralization patterns, but not tesserae, and evidence for a paedomorphic chimaera skeleton

Atake, O. J.; Berio, F.; Debiais Thibaud, M.; F Eames, B.

10.1101/2024.01.07.574539 — evolutionary biology — Posted on 2024-01-08

3692 Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka

Manamperi, N. H.; Edirisinghe, N. M.; Wijesinghe, H.; Pathiraja, L.; Pathirana, N.; Wanasinghe, V. S.; De Silva, C. G.; Abeyewickreme, W.; Karunaweera, N. D.

10.1101/2024.01.07.574579 — molecular biology — Posted on 2024-01-08

3693 Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis

Secli, V.; Michetti, E.; Pacello, F.; Iacovelli, F.; Falconi, M.; Astolfi, M. L.; Visaggio, D.; Visca, P.; Ammendola, S.; Battistoni, A.

10.1101/2024.01.07.574578 — microbiology — Posted on 2024-01-08

3694 De-glycosylated non-structural protein 1 enhances dengue virus clearance by limiting PD-L1/PD-1 mediated T cell apoptosis

Hj Idris, F.; Ting, D. H. R.; Tan, E. T. X.; Wan, C.; Chan, K. R.; Benke, P. I.; Marzinek, J. K.; Copping, J. M.; Li, Q. H.; Walsh, I.; Allison, J. R.; Bond, P. J.; Torta, F. T.; Nguyen-Khuong, T.; ALONSO, S.

10.1101/2024.01.08.574590 — microbiology — Posted on 2024-01-08

3695 Candidatus Nitrosocosmicus members are the dominant archaea associated with pepper (Capsicum annuum L.) and ginseng (Panax ginseng C.A. Mey.) plants rhizospheres

Lee, U.-J.; Gwak, J.-H.; Choi, S.; Jung, M.-Y.; Lee, T. K.; Ryu, H.; Awala, S. I.; Wanek, W.; Wagner, M.; Quan, Z.-X.; Rhee, S.-K.

10.1101/2024.01.08.574571 — microbiology — Posted on 2024-01-08

3696 The Emerging Role of 3-Hydroxyanthranilic Acid on C. elegans Aging Immune Function

Espejo, L. S.; DeNicola, D. D.; Chang, L. M.; Silbar, V. D.; Haskins, A. E.; Antenor, A. B.; Balsa, J. r.; Freitas, S.; Hamming, S.; Hull, B.; Dang, H.; Castro-Portuguez, R.; Sutphin, G. L.

10.1101/2024.01.07.574394 — immunology — Posted on 2024-01-08

3697 Concerted neuron-astrocyte gene expression declines in aging and schizophrenia

Ling, E.; Nemesh, J.; Goldman, M.; Kamitaki, N.; Reed, N.; Handsaker, R. E.; Genovese, G.; Vogelgsang, J. S.; Gerges, S.; Kashin, S.; Ghosh, S.; Esposito, J. M.; French, K.; Meyer, D.; Lutservitz, A.; Mullally, C. D.; Wysoker, A.; Spina, L.; Neumann, A.; Hogan, M.; Ichihara, K.; Berretta, S.; McCarroll, S. A.

10.1101/2024.01.07.574148 — neuroscience — Posted on 2024-01-08

3698 The role of conscious attention in statistical learning: evidence from patients with impaired consciousness

Benjamin, L.; Zang, D.; Flo, A.; Qi, Z.; Su, P.; Zhou, W.; Wang, L.; Wu, X.; Gui, P.; Dehaene-Lambertz, G.

10.1101/2024.01.08.574591 — neuroscience — Posted on 2024-01-08

3699 The cervical and meningeal lymphatic network as a pathway for retrograde nanoparticle transport to the brain

Ramos-Zaldivar, H. M.; Polakovicova, I.; Salas-Huenuleo, E.; Yefi, C. P.; Silva, D.; Jara-Guajardo, P.; Oyarzun, J. E.; Neira-Troncoso, A.; Burgos, P. V.; Cavieres, V. A.; Arias-Munoz, E.; Martinez, C.; Riveros, A. L.; Corvalan, A. H.; Kogan, M. J.; Andia, M. E.

10.1101/2024.01.06.574478 — neuroscience — Posted on 2024-01-08

3700 The suprapyramidal and infrapyramidal blades of the dentate gyrus exhibit different GluN subunit content and dissimilar frequency-dependent synaptic plasticity in vivo

Strauch, C.; Boege, J.; Shchyglo, O.; Dubovyk, V.; Manahan-Vaughan, D.

10.1101/2024.01.08.574587 — neuroscience — Posted on 2024-01-08

3701 Recognition and localization of maize leaves in RGB images based on Point-Line Net

Liu, B.; Chang, J.; Hou, D.; Li, D.; Ruan, J.

10.1101/2024.01.08.574560 — plant biology — Posted on 2024-01-08

3702 A network toxicology approach for mechanistic modelling of nanomaterial hazard and adverse outcomes

del Giudice, G.; Serra, A.; Pavel, A.; Torres Maia, M.; Saarimäki, L. A.; Fratello, M.; Federico, A.; Alenius, H.; Fadeel, B.; Greco, D.

10.1101/2024.01.06.574295 — pharmacology and toxicology — Posted on 2024-01-08

3703 Thermodynamic Characterization of LC3/GABARAP Ligands byIsothermal Titration Calorimetry

Dopfer, J.; Schwalm, M. P.; Knapp, S.; Rogov, V. V.

10.1101/2024.01.08.574610 — biochemistry — Posted on 2024-01-08

3704 Risking your Tail: Modeling Individual Differences in Risk-sensitive Exploration using Conditional Value at Risk and Bayes Adaptive Markov Decision Processes

Shen, T.; Dayan, P.

10.1101/2024.01.07.574574 — animal behavior and cognition — Posted on 2024-01-08

3705 Changes in enclosure use and basking behaviour associated with pair housing in Tokay geckos (Gekko gecko)

Szabo, B.

10.1101/2024.01.08.574605 — animal behavior and cognition — Posted on 2024-01-08

3706 Modeling Combination Chemo-Immunotherapy for Heterogeneous Tumors

Chen, S.; Hu, Z.; Zhou, D.

10.1101/2024.01.07.574576 — evolutionary biology — Posted on 2024-01-08

3707 Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a significant decrease of human exposure to the disease

Kagbadouno, M. S.; SERE, M.; Segard, A.; Camara, A. D.; Camara, M.; BUCHETON, B.; Bart, J.-M.; Courtin, F.; DE MEEUS, T.; Ravel, S.

10.1101/2023.07.25.550445 — evolutionary biology — Posted on 2024-01-08

3708 Understanding feeding competition under laboratory conditions: Rohu (Labeo rohita) versus Amazon sailfin catfish (Pterygoplichthys spp.)

Mallick, S.; Sundaray, J. K.; Ghosal, R.

10.1101/2024.01.06.574454 — ecology — Posted on 2024-01-08

3709 Studies of vegetation and land-use history on Bodmin Moor: pollen investigations from Leskernick

Waller, M. P.

10.1101/2024.01.05.574344 — ecology — Posted on 2024-01-08

3710 Use of linear features by red-legged partridges in an intensive agricultural landscape: implications for landscape management in farmland

Perrot, C.; Berceaux, A.; Noel, M.; Arroyo, B.; Bacon, L.

10.1101/2023.07.27.550774 — ecology — Posted on 2024-01-08

3711 Fibronectin 1 is a novel biomarker of obstetric antiphospholipid syndrome

xu, j.; chung, t.; hu, z.; tian, y.; ling, q.; WANG, X.; PENG, B.

10.1101/2024.01.08.574588 — developmental biology — Posted on 2024-01-08

3712 MUM, a maternal unknown message, inhibits early establishment of the mediolateral axis in the embryo of the kelp Saccharina latissima

Boscq, S.; Billoud, B.; Theodorou, I.; Joemmanbaks, T.; Charrier, B.

10.1101/2024.01.07.574535 — developmental biology — Posted on 2024-01-08

3713 Self-balanced regulation by the long non-coding RNA Lockd on the cell cycle progression of cortical neural progenitor cells through counteracting cis and trans roles

Qi, S.; Zheng, J.; Shen, Q.

10.1101/2024.01.08.574564 — developmental biology — Posted on 2024-01-08

3714 Unbiased identification of cell identity in dense mixed neural cultures

De Beuckeleer, S.; Van De Looverbosch, T.; Van Den Daele, J.; Ponsaerts, P.; De Vos, W.

10.1101/2024.01.06.574474 — cell biology — Posted on 2024-01-08

3715 Morphological Reprogramming of Primary Cilia Length Mitigates the Fibrotic Phenotype in fibroblasts across diverse fibrotic conditions

Verma, P.; Yalavarthi, B.; Bhattacharyya, S.; Khanna, D.; Gudjonsson, J. E.; Tsoi, L. C.; Wells, R.; Ross, R. L.; Riobo-Del Galdo, N.; Del Galdo, F.; Fortier, S. M.; Teves, M. E.; Varga, J.; Bhattacharyya, D.

10.1101/2024.01.06.574461 — cell biology — Posted on 2024-01-08

3716 Shaping up genomes: Prokaryotic roots and eukaryotic diversification of SMC complexes

van Hooff, J. J. E.; Raas, M. W. D.; Tromer, E. C.; Eme, L.

10.1101/2024.01.07.573240 — cell biology — Posted on 2024-01-08

3717 Mathematical model for rod outer segment dynamics during retinal detachment and reattachment

Annan, W. E.; Annan, E. O. A.; White, D.

10.1101/2024.01.08.574604 — cell biology — Posted on 2024-01-08

3718 Cytochrome P450 Enzyme Design by Constraining Catalytic Pocket in Diffusion model

Wang, Q.; Liu, X.; Zhang, H.; Chu, H.; Shi, C.; Chang, Z.; Cheng, J.; Jiang, H.

10.1101/2024.01.08.574609 — molecular biology — Posted on 2024-01-08

3719 Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation

Cable, J. M.; White, R. E.; Reinoso-Vizcaino, N. M.; Luftig, M. A.

10.1101/2024.01.07.574580 — microbiology — Posted on 2024-01-08

3720 The conserved σD envelope stress response monitors multiple aspects of envelope integrity in corynebacteria

Hart, E.; Lyerly, E.; BERNHARDT, T.

10.1101/2024.01.07.574573 — microbiology — Posted on 2024-01-08

3721 Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease

10.1101/2024.01.07.574561 — immunology — Posted on 2024-01-08

3722 A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy

Seyedsadr, M.; Bang, M.; McCarthy, E.; Zhang, S.; Chen, H.-C.; Mohebbi, M.; HUGO, W.; Whitmire, J. K.; Lechner, M. G.; Su, M.

10.1101/2024.01.07.574553 — immunology — Posted on 2024-01-08

3723 Identification of Novel Biomarkers for Alzheimer's Disease and Related Dementias Using Unbiased Plasma Proteomics

Lacar, B.; Ferdosi, S.; Alavi, A.; Stukalov, A.; Venkataraman, G. R.; de Geus, M.; Dodge, H.; Wu, C.-Y.; Kivisakk, P.; Das, S.; Guturu, H.; Hyman, B.; Batzoglou, S.; Arnold, S. E.; Siddiqui, A.

10.1101/2024.01.05.574446 — neuroscience — Posted on 2024-01-08

3724 Behaviour-based movement cut-off points in 3-year old children comparing wrist- with hip-worn actigraphs MW8 and GT3X

Jansson, D.; Westlander, R.; Sandlund, J.; West, C.; Domellof, M.; Wulff, K.

10.1101/2024.01.06.574473 — neuroscience — Posted on 2024-01-08

3725 Poor decision making and sociability impairment following central serotonin reduction in inducible TPH2-knockdown rats

Alonso, L.; Peeva, P.; Fernandez del valle Alquicira, T.; Erdelyi, N.; Gil-Nolskog, A.; Bader, M.; Winter, Y.; Alenina, N.; Rivalan, M.

10.1101/2024.01.06.574479 — neuroscience — Posted on 2024-01-08

3726 Nitrogen Management on Improving Resilience of Flood-Tolerant (Sub1) Rice Varieties in Flood-Prone Rainfed Lowlands

Singh, A. K.; Pandey, A. K.; Singh, A.; Tiwari, D.; Singh, B.

10.1101/2024.01.05.574436 — plant biology — Posted on 2024-01-08

3727 Linkers in bitopic agonists shape bias profile among transducers for the dopamine D2 and D3 receptors

Semeano, A.; Garland, R.; Bonifazi, A.; Lee, K. H.; Famiglietti, J.; Zhang, W.; Jo, Y. J.; Battiti, F. O.; Shi, L.; Newman, A. H.; Yano, H.

10.1101/2024.01.07.574547 — pharmacology and toxicology — Posted on 2024-01-08

3728 Creating cell-specific computational models of stem cell-derived cardiomyocytes using optical experiments

Yang, J.; Daily, N.; Pullinger, T. K.; Wakatsuki, T.; Sobie, E. A.

10.1101/2024.01.07.574577 — pharmacology and toxicology — Posted on 2024-01-08

3729 Effect of RNA m6A methyltransferase activation by a low molecular weight compound on anxiety- and depression-related behaviours, monoamine neurochemistry and striatal gene expression in the rat

Kanarik, M.; Liiver, K.; Skolnaja, M.; Teino, I.; Org, T.; Laugus, K.; Shimmo, R.; Karelson, M.; Saarma, M.; Harro, J.

10.1101/2024.01.08.574593 — pharmacology and toxicology — Posted on 2024-01-08

3730 A BODIPY-naphtholimine-BF2 dyad for precision photodynamic therapy, targeting and dual imaging of endoplasmic reticulum and lipid droplets in cancer

Patro, B. S.; Chauhan, N.; Koli, M.; Mula, S. M.; Ghanty, T.; Majumdar, A. G.

10.1101/2024.01.07.574513 — cancer biology — Posted on 2024-01-08

3731 Mean Shift Clustering as a Loss Function for Accurate and Segmentation-aware Localization of Macromolecules in Cryo-electron Tomography

Lamm, L.; Righetto, R. D.; Peng, T.

10.1101/2024.01.05.574361 — bioinformatics — Posted on 2024-01-08

3732 MATE-Pred: Multimodal Attention-based TCR-Epitope interaction Predictor

Goffinet, E.; Mall, R.; Singh, A.; Kaushik, R.; Castiglione, F.

10.1101/2024.01.07.574567 — bioinformatics — Posted on 2024-01-08

3733 COFFEE: CONSENSUS SINGLE CELL-TYPE SPECIFIC INFERENCE FOR GENE REGULATORY NETWORKS

Lodi, M.; Chernikov, A.; Ghosh, P.

10.1101/2024.01.05.574445 — bioinformatics — Posted on 2024-01-08

3734 Demonstration of chemotherapeutic mediated lymphatic changes in meningeal lymphatics in vitro, ex vivo, and in vivo

Roberts, L. M.; Hammel, J. H.; Azar, F.; Feng, T.-Y.; Cunningham, J. J.; Rutkowski, M. R.; Munson, J.

10.1101/2024.01.06.574460 — bioengineering — Posted on 2024-01-08

3735 Effect of Artificial Lung Fiber Bundle Geometric Design on Micro- and Macro-scale Clot Formation

Lai, A.; Omori, N.; Napolitano, J. E.; Antaki, J. F.; Cook, K.

10.1101/2024.01.05.574443 — bioengineering — Posted on 2024-01-08

3736 Development and validation of a subject-specific integrated finite element musculoskeletal model of human trunk with ergonomic and clinical applications

Ghezelbash, F.; Eskandari, A. H.; Shirazi-Adl, A.; Lariviere, C.

10.1101/2024.01.06.574467 — bioengineering — Posted on 2024-01-08

3737 Development of a 3D vascular network visualization platform for one-dimensional hemodynamic simulation

Chen, Y.; Kobayashi, M.; Yuhn, C.; Oshima, M.

10.1101/2024.01.08.574602 — bioengineering — Posted on 2024-01-08

3738 Data-driven system matrix manipulation enabling fast functional imaging and intra-image nonrigid motion correction in tomography

Hu, P.; Tong, X.; Lin, L.; Wang, L.

10.1101/2024.01.07.574504 — bioengineering — Posted on 2024-01-08

3739 Enabling Systemic Identification and Functionality Profiling for Cdc42 Homeostatic Modulators

Malasala, S.; Azimian, F.; Chen, Y.-H.; Twiss, J. L.; Boykin, C.; Nik Akhtar, S.; Lu, Q.

10.1101/2024.01.05.574351 — biochemistry — Posted on 2024-01-08

3740 Heparan sulfate selectively inhibits the collagenase activity of cathepsin K

Zhang, X.; Luo, Y.; Hao, H.; Krahn, J.; Su, G.; Dutcher, R.; Xu, Y.; Liu, J.; Pedersen, L.; Xu, D.

10.1101/2024.01.05.574350 — biochemistry — Posted on 2024-01-08

3741 Genomic analyses capture the human-induced demographic collapse and recovery in a wide-ranging cervid

Kessler, C.; Shafer, A.

10.1101/2023.07.19.549627 — genomics — Posted on 2024-01-08

3742 Chromosome-scale genome assembly of Camellia crapnelliana provides insights into the fatty acid biosynthesis

Gao, L.-z.; Zhang, F.; Feng, L.-y.; Lin, P.-f.; Jia, J.-j.

10.1101/2024.01.07.574508 — genomics — Posted on 2024-01-08

3743 All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency.

Hayward, B. E.; Usdin, K.; Kumari, D.; van Kuilenburg, A. B.; van Karnebeek, C. D. M.

10.1101/2023.12.26.573357 — genetics — Posted on 2024-01-08

3744 The concept of the gain curve

Burd, M.

10.1101/2024.01.07.574552 — evolutionary biology — Posted on 2024-01-08

3745 Climate change, age acceleration, and the erosion of fitness in polar bears

Newediuk, L.; Richardson, E. S.; Biddlecombe, B. A.; Kassim, H.; Kathan, L.; Lunn, N.; Rivkin, L. R.; Salama, O. E.; Schmidt, C.; Jones, M. J.; Garroway, C. J.

10.1101/2024.01.05.574416 — ecology — Posted on 2024-01-08

3746 Strata use in a canopy-beetle community of a lowland Neotropical rainforest in southern Venezuela

Kirmse, S.

10.1101/2024.01.07.574520 — ecology — Posted on 2024-01-08

3747 Beta-Cell Pyroptosis - A Burning Flame in Type 1 Diabetes?

Frorup, C.; Sondergaard Svane, C. A.; Henriksen, K.; Kaur, S.; Storling, J.

10.1101/2024.01.05.574294 — cell biology — Posted on 2024-01-08

3748 Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

Thomas, J. R.; Frye, W. J. E.; Robey, R. W.; Warner, A. C.; Butcher, D.; Matta, J. L.; Morgan, T. C.; Edmondson, E. F.; Salazar, P. B.; Ambudkar, S.; Gottesman, M. M.

10.1101/2023.05.18.539313 — cell biology — Posted on 2024-01-08

3749 Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathway.

Herrmannova, A.; Jelinek, J.; Pospisilova, K.; Kerenyi, F.; Vomastek, T.; Watt, K.; Brabek, J.; Mohammad, M. P.; Wagner, S.; Topisirovic, I.; Valasek, L. S.

10.1101/2023.06.29.547003 — molecular biology — Posted on 2024-01-08

3750 Neural populations in the language network differ in the size of their temporal receptive windows

Regev, T. I.; Casto, C.; Hosseini, E. A.; Adamek, M.; Ritaccio, A. L.; Willie, J. T.; Brunner, P.; Fedorenko, E.

10.1101/2022.12.30.522216 — neuroscience — Posted on 2024-01-08

3751 The Subcortical Atlas of the Marmoset (SAM) monkey based on high-resolution MRI and histology

Saleem, K. S.; Avram, A. V.; Glen, D.; Schram, V.; Basser, P. J.

10.1101/2024.01.06.574429 — neuroscience — Posted on 2024-01-08

3752 Intestinal flow rates, absorption of felodipine from the small intestine and attributes of chyme collected at midgut from Labradors

Diebold, S. M.

10.1101/2024.01.05.574377 — physiology — Posted on 2024-01-08

3753 Chromatin network rearrangements in differentiation and cancer reveal connections between evolutionary processes and gene regulation

Aliaga, B.; Raynal, F.; Sengupta, K.; Plewczynski, D.; Pancaldi, V.

10.1101/2023.10.30.564438 — cancer biology — Posted on 2024-01-08

3754 Revealing sphingolipids composition in extracellular vesicles and paternal β-cells after persistent hyperglycemia

Skalska, M.; Durak-Kozica, M.; Stepien, E. L.

10.1101/2024.01.06.574464 — biophysics — Posted on 2024-01-08

3755 Combinatorial prediction of therapeutic perturbations using causally-inspired neural networks

Gonzalez, G.; Herath, I.; Veselkov, K.; Bronstein, M.; Zitnik, M.

10.1101/2024.01.03.573985 — bioinformatics — Posted on 2024-01-08

3756 Targeting glioblastoma tumor hyaluronan to enhance therapeutic interventions that regulate metabolic cell properties

Neves, E.; Anand, A.; Mueller, J.; Remy, R.; Xu, H.; Selting, K.; Sarkaria, J. N.; Harley, B.; Pedron-Haba, S.

10.1101/2024.01.05.574065 — bioengineering — Posted on 2024-01-08

3757 Sucrose phosphorylase from Alteromonas mediterranea: structural insight into the regioselective α-glucosylation of (+)-catechin

GOUX, M.; Demonceaux, M.; Hendrickx, J.; Solleux, C.; LORMEAU, E.; Fredslund, F.; Teze, D.; Offmann, B. G.; Miral, C.

10.1101/2023.04.11.536264 — biochemistry — Posted on 2024-01-08

3758 Stable long-term individual variation in chimpanzee technological efficiency

Berdugo, S.; Cohen, E.; Davis, A. J.; Matsuzawa, T.; Carvalho, S.

10.1101/2023.11.21.568000 — animal behavior and cognition — Posted on 2024-01-08

3759 Gene-environment correlation: The role of family environment in academic development

Zhou, Q.; Gidziela, A.; Allegrini, A. G.; Cheesman, R.; Wertz, J.; Maxwell, J.; Plomin, R.; Rimfeld, K.; Malanchini, M.

10.1101/2024.01.05.574339 — genetics — Posted on 2024-01-08

3760 Methionine oxidation of Carbohydrate-Active enZymes during white-rot wood decay

Molinelli, L.; Drula, E.; GAILLARD, J.-C.; Navarro, D.; Armengaud, J.; Berrin, J.-G.; Tron, T.; Tarrago, L.

10.1101/2023.10.24.563746 — microbiology — Posted on 2024-01-08

3761 An antimicrobial peptide expression platform for targeting pathogenic bacterial species

Rutter, J. W.; Dekker, L.; Clare, C.; McDonald, J. A.; Nair, S. P.; Fedorec, A. J.; Barnes, C. P.

10.1101/2023.10.09.561505 — synthetic biology — Posted on 2024-01-08

3762 {xi}-π: a nonparametric model for neural powerspectra decomposition

Hu, S.; Zhang, Z.; Wu, X.; Valdes-Sosa, P. A.

10.1101/2023.12.03.569765 — bioinformatics — Posted on 2024-01-08

3763 Protein language model embedded geometric graphs power inter-protein contact prediction

Si, Y.; Yan, C.

10.1101/2023.01.07.523121 — bioinformatics — Posted on 2024-01-08

3764 Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations

Lou, J.; Liang, W.; Cao, L.; Zhao, S.; Chen, Z.; Chan, R. W.; Cheung, P. P. H.; Zheng, H.; Liu, C.; Li, Q.; Chong, M.; Zhang, Y.; Yeoh, E.-k.; Chan, P. K.; Zee, B.; Mok, C. K.-P.; Wang, M. H.

10.1101/2023.08.23.554557 — evolutionary biology — Posted on 2024-01-08

3765 A developmental brain-wide screen identifies retrosplenial cortex as a key player in the emergence of persistent memory

Jin, B.; Gongwer, M. W.; Ohanian, L.; Holden-Wingate, L.; Le, B.; Darmawan, A.; Nakayama, Y.; Mora, S. A. R.; DeNardo, L. A.

10.1101/2024.01.07.574554 — neuroscience — Posted on 2024-01-08

3766 Conserved Cardiovascular Network: Bioinformatics Insights into Genes and Pathways for Establishing Caenorhabditis elegans as an Animal Model for Cardiovascular Diseases.

Ray, A. K.; Priya, A.; Malik, M. Z.; Thanaraj, T. A.; Singh, A. K.; Mago, P.; Ghosh, C.; Shalimar, ; Tandon, R.; Chaturvedi, R.

10.1101/2023.12.24.573256 — systems biology — Posted on 2024-01-08

3767 Self-organized emergence of modularity, hierarchy, and mirror reversals from competitive synaptic growth in a developmental model of the visual pathway

Chandra, S.; Khona, M.; Konkle, T.; Fiete, I.

10.1101/2024.01.07.574543 — neuroscience — Posted on 2024-01-08

3768 Acquisition phase-specific contribution of climbing fiber transmission to cerebellum-dependent motor memory

Seo, J.; Kim, S. H.; Lee, J.; Kim, M. S.; Lee, Y.-S.; Kim, S. J.

10.1101/2024.01.06.574489 — neuroscience — Posted on 2024-01-08

3769 Biomechanical comparison of plate materials and designs for subcondylar fracture fixation: An in silico assessment

Gupta, A.; Dutta, A.; Dutta, K.; Mukherjee, K.

10.1101/2023.08.07.552268 — bioengineering — Posted on 2024-01-07

3770 Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway

Yan, H.; Liu, Y.; Li, X.; Yu, B.; He, J.; Mao, X.; Yu, J.; Huang, Z.; Luo, Y.; Luo, J.; Wu, A.; Chen, D.

10.1101/2023.06.21.546014 — immunology — Posted on 2024-01-07

3771 Cortical and subcortical brain networks predict prevailing heart rate

Sentis, A. I.; Rasero, J.; Gianaros, P. J.; Verstynen, T. V.

10.1101/2023.09.23.559114 — neuroscience — Posted on 2024-01-07

3772 Species-specific design of artificial promoters by transfer-learning based generative deep-learning model

Xia, Y.; Du, X.; Liu, B.; Guo, S.; Huo, Y.-X.

10.1101/2023.12.27.573416 — synthetic biology — Posted on 2024-01-07

3773 Longer mandible or nose? Co-evolution of feeding organs in early elephantiforms

Li, C.; Deng, T.; Wang, Y.; Sun, F.; Wolff, B.; Jiangzuo, Q.; Ma, J.; Xing, L.; Fu, J.; Zhang, J.; Wang, S.

10.1101/2023.08.15.553347 — paleontology — Posted on 2024-01-07

3774 STASCAN deciphers fine-resolution cell-distribution maps in spatial transcriptomics by deep learning

Wu, Y.; Zhou, J.-Y.; Yao, B.; Cui, G.; Zhao, Y.-L.; Gao, C.-C.; Yang, Y.; Zhang, S.; Yang, Y.-G.

10.1101/2023.09.02.556029 — bioinformatics — Posted on 2024-01-07

3775 CAP peptide artificially induces insect gall

Sakamoto, T.; Kimura, S.; Nakayama, T.; Sato, M. P.; Shirasawa, K.; Sato, M. H.; Hirano, T.

10.1101/2024.01.06.574462 — molecular biology — Posted on 2024-01-07

3776 BBB recovery after stroke by self-replenishing E-pericytes transdifferentiated from local endothelial cells.

Li, T.-B.; Jia, J.-M.; Tu, J.-Q.; Gao, Q.-Z.; Zhu, Z.; Li, X.-Z.; Jin, Y.-X.; Zhang, Y.-Y.; Xie, J.-F.; Zhu, P.-R.; Zhao, B.-R.

10.1101/2024.01.07.573171 — molecular biology — Posted on 2024-01-07

3777 Targeted phage hunting to specific Klebsiella pneumoniae clinical isolates is an efficient antibiotic resistance and infection control strategy

Ferriol-Gonzalez, C.; Concha-Eloko, R.; Bernabeu-Gimeno, M.; Fernandez-Cuenca, F.; Canada-Garcia, J. E.; Garcia-Cobos, S.; Sanjuan, R.; Domingo-Calap, P.

10.1101/2024.01.07.574526 — microbiology — Posted on 2024-01-07

3778 Genetic Toolbox for Photorhabdus and Xenorhabdus: pSEVA based heterologous expression systems and CRISPR/Cpf1 based genome editing for rapid natural product profiling

Rill, A.; Zhao, L.; Bode, H. B.

10.1101/2024.01.07.574529 — microbiology — Posted on 2024-01-07

3779 Synthetase and Hydrolase Specificity Collectively Excludes Deoxyguanosine from Bacterial Alarmone

Zhou, R. W.; Gordon, I. J.; Hei, Y.; Wang, B.

10.1101/2024.01.06.574488 — microbiology — Posted on 2024-01-07

3780 Protecting Allogeneic Pancreatic Islet Grafts by Engineered Veto

Qi, Y.; Zhang, X.; Cull, J. W.; McCoy, P.; Cruz, C.; Dahl, K.; Staerz, U. D.

10.1101/2024.01.05.574389 — immunology — Posted on 2024-01-07

3781 The sea urchin Paracentrotus lividus orients to visual stimuli

Kirwan, J. D.; Li, T.; Ullrich-Lueter, J.; La Camera, G.; Nilsson, D.-E.; Arnone, M. I.

10.1101/2024.01.05.574409 — zoology — Posted on 2024-01-07

3782 Lettuce seedlings rapidly assemble their microbiome from the environment through deterministic processes

Zakaria Mohamed, N.; Schena, L.; Malacrino, A.

10.1101/2024.01.05.574372 — plant biology — Posted on 2024-01-07

3783 mRNA initiation and termination are spatially coordinated

Calvo-Roitberg, E.; Carroll, C. L.; Venev, S. V.; Kim, G.; Mick, S. T.; Dekker, J.; Fiszbein, A.; Pai, A. A.

10.1101/2024.01.05.574404 — genomics — Posted on 2024-01-07

3784 Reprogramming of 3D genome structure underlying HSPC development in zebrafish

He, M.; Li, X.; Xu, B.; Lu, Y.; Liu, H.; Yang, A.; Zhang, W.; Li, F.

10.1101/2024.01.06.574496 — genomics — Posted on 2024-01-07

3785 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

Gao, X.; Zhang, B.; Liu, P.; Yuwen, M.; Liu, Z.; Tan, R.; Wang, B.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Liu, L.; Zhu, C.; Wang, T.; Li, S.; Kang, J.

10.1101/2024.01.06.574490 — cell biology — Posted on 2024-01-07

3786 Diverse bacteriohemerythrin genes of Methylomonas denitrificans FJG1 provide insight into the survival and activity of proteobacterial methanotrophs under hypoxia

Weiblen, C.; Sauvageau, D.; Stein, L. Y.

10.1101/2024.01.07.574550 — microbiology — Posted on 2024-01-07

3787 Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice

Lee, S.-Y.; Fontana, F.; Sugatani, T.; Portales-Castillo, I.; Leanza, G.; Coler-Reilly, A.; Civitelli, R.

10.1101/2024.01.05.574415 — physiology — Posted on 2024-01-07

3788 PHF6 suppresses self-renewal of leukemic stem cells in AML

Jalnapurkar, S. S.; Pawar, A.; George, S. S.; Antony, C.; Grana, J.; Gurubuxani, S.; Paralkar, V. R.

10.1101/2024.01.06.573649 — cancer biology — Posted on 2024-01-07

3789 Deciphering the diversity and sequence of extracellular matrix and cellular spatial patterns in lung adenocarcinoma using topological data analysis

Yoon, I. H. R.; Jenkins, R.; Colliver, E.; Zhang, H.; Novo, D.; Moore, D.; Ramsden, Z.; Rullan, A.; Fu, X.; Yuan, Y.; Harrington, H. A.; Swanton, C.; Byrne, H. M.; Sahai, E.

10.1101/2024.01.05.574362 — cancer biology — Posted on 2024-01-07

3790 Comparing multifunctional viral and eukaryotic proteins for generating scission necks in membranes

Alimohamadi, H.; Luo, E. W.-C.; Gupta, S.; Anda, J. d.; Yang, R.; Mandal, T.; Wong, G.

10.1101/2024.01.05.574447 — biophysics — Posted on 2024-01-07

3791 High-resolution Molecular Dynamics Simulations of the Pyruvate Kinase Muscle Isoform 1 and 2 (PKM1/2)

Delobelle, Q.; Jaffrelot-Inizan, T.; Adjoua, O. P.; Lagardere, L.; Celerse, F.; Marechal, V.; Piquemal, J.-P.

10.1101/2024.01.07.574528 — biophysics — Posted on 2024-01-07

3792 An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data

Mehlman, T.; Ginn, H. M.; Keedy, D. A.

10.1101/2024.01.05.574428 — biophysics — Posted on 2024-01-07

3793 Balancing stability, dynamics and kinetics in phase separation of intrinsically disordered proteins

Zhang, G.; Chu, X.

10.1101/2024.01.05.574441 — biophysics — Posted on 2024-01-07

3794 Charting Single Cell Lineage Dynamics and Mutation Networks via Homing CRISPR

Wong, S. T.; Wang, L.; Dong, W.; Yin, Z.; Sheng, J.; Ezeana, C. F.; Yang, L.; Yu, X.; Wong, S. S.; Wan, Z.; Danforth, R. L.; Han, K.; Gao, D.

10.1101/2024.01.05.574236 — bioinformatics — Posted on 2024-01-07

3795 Predicting Serotonin Detection with DNA-Carbon Nanotube Sensors Across Multiple Spectral Wavelengths

Kelich, P.; Adams, J.; Jeong, S.; Navarro, N.; Landry, M. P.; Vukovic, L.

10.1101/2024.01.06.574485 — bioengineering — Posted on 2024-01-07

3796 A precision microgel platform to direct vascular morphogenesis in vitro

Kuehn, S.; Magno, V.; Zimmermann, R.; Limasale, Y.; Atallah, P.; Stoppa, A.; Maennel, M.; Thiele, J.; Freudenberg, U.; Werner, C.

10.1101/2024.01.05.574387 — bioengineering — Posted on 2024-01-07

3797 Mycobacterium tuberculosis exploits SIRT2 for iron acquisition to facilitate its intracellular survival

Talukdar, S.; Modanwal, R.; Chaubey, G. K.; Dhiman, A.; Dilawari, R.; Raje, C. I.; Raje, M.

10.1101/2024.01.05.574348 — cell biology — Posted on 2024-01-07

3798 TDP-43 pathology links innate and adaptive immunity in amyotrophic lateral sclerosis

10.1101/2024.01.07.574541 — cell biology — Posted on 2024-01-07

3799 CD177 is a novel IgG Fc receptor and CD177 genetic variants affect IgG-mediated function

Wu, J.; Li, Y.

10.1101/2024.01.07.574546 — immunology — Posted on 2024-01-07

3800 Agonist efficacy at the B2AR is driven by agonist-induced differences in receptor affinity for the Gs protein, not ligand binding kinetics.

Harwood, C. R.; Sykes, D. A.; Redfern-Nichols, T.; Ladds, G.; Briddon, S. J.; Veprintsev, D.

10.1101/2024.01.05.574357 — pharmacology and toxicology — Posted on 2024-01-07

3801 Comparison of urine proteome between obese people and normal weight people

Wang, H.; Wei, L.; Zhou, Y.; Cao, Y.; Gao, Y.

10.1101/2024.01.06.574495 — biochemistry — Posted on 2024-01-07

3802 Effect of Pressure on the Conformational Landscape of Human γD-crystallin from Replica Exchange Molecular Dynamics Simulations

Kacirani, A.; Uralcan, B.; Domingues, T. S.; Haji-Akbari, A.

10.1101/2024.01.07.574493 — biochemistry — Posted on 2024-01-07

3803 Three-dimensional Label-Free Measurements of Adipocyte Differentiation and Lipid Droplet Dynamics

Jeong, E. Y.; Kim, H.-J.; Lee, S.; Park, Y.; Kim, Y. M.

10.1101/2024.01.06.574492 — biochemistry — Posted on 2024-01-07

3804 Intracortical recordings reveal Vision-to-Action cortical gradients driving human exogenous attention

Seidel Malkinson, T.; Bayle, D. J.; Kaufmann, B. C.; Liu, J.; Bourgeois, A.; Lehongre, K.; Fernandez-Vidal, S.; Navarro, V.; Adam, C.; Margulies, D. S.; Sitt, J. D.; Bartolomeo, P.

10.1101/2021.01.02.425103 — neuroscience — Posted on 2024-01-07

3805 Unlocking de novo antibody design with generative artificial intelligence

Shanehsazzadeh, A.; McPartlon, M.; Kasun, G.; Steiger, A. K.; Sutton, J. M.; Yassine, E.; McCloskey, C.; Haile, R.; Shuai, R.; Alverio, J.; Rakocevic, G.; Levine, S.; Cejovic, J.; Gutierrez, J. M.; Morehead, A.; Dubrovskyi, O.; Chung, C.; Luton, B. K.; Diaz, N.; Kohnert, C.; Consbruck, R.; Carter, H.; LaCombe, C.; Bist, I.; Vilaychack, P.; Anderson, Z.; Xiu, L.; Bringas, P.; Alarcon, K.; Knight, B.; Radach, M.; Bateman, K.; Kopec-Belliveau, G.; Chapman, D.; Bennett, J.; Ventura, A. B.; Canales, G. M.; Gowda, M.; Jackson, K. A.; Caguiat, R.; Brown, A.; Ganini da Silva, D.; Guo, Z.; Abdulhaqq, S

10.1101/2023.01.08.523187 — synthetic biology — Posted on 2024-01-07

3806 Differential effects of multiplex and uniplex affiliative relationships on biomarkers of inflammation

Vandeleest, J. J.; Wooddell, L. J.; Nathman, A. C.; Beisner, B. A.; McCowan, B.

10.1101/2022.11.01.514247 — animal behavior and cognition — Posted on 2024-01-07

3807 Evolutionary Rate Covariation is a reliable predictor of co-functional interactions but not necessarily physical interactions

Little, J.; Chikina, M.; Clark, N. L.

10.1101/2023.10.18.562970 — evolutionary biology — Posted on 2024-01-07

3808 Interactions between saccades and smooth pursuit eye movements in marmosets

Pattadkal, J. J.; Barr, C.; Priebe, N. J.

10.1101/2024.01.07.574533 — neuroscience — Posted on 2024-01-07

3809 Characterization of Gαs and Gαolf activation by catechol and non-catechol dopamine D1 receptor agonists

Nguyen, A. M.; Semeano, A.; Quach, V.; Inoue, A.; Nichols, D. E.; Yano, H.

10.1101/2023.10.03.560682 — pharmacology and toxicology — Posted on 2024-01-07

3810 Machine Learning Models to Interrogate Proteomewide Covalent Ligandabilities Directed at Cysteines

Liu, R.; Clayton, J.; Shen, M.; Bhatnagar, S.; Shen, J.

10.1101/2023.08.17.553742 — biophysics — Posted on 2024-01-07

3811 Impact of high fat diet and exercise on bone and bile acid metabolism in rats

Alonso, N.; Almer, G.; Semeraro, M. D.; Rodriguez-Blanco, G.; Fauler, G.; Anders, I.; Ritter, G.; vom Scheidt, A.; Hammer, N.; Gruber, H. J.; Herrmann, M.

10.1101/2024.01.07.573992 — molecular biology — Posted on 2024-01-07

3812 Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes

Truesdell, P.; Chang, J.; Coto Villa, D.; Zhao, Y.; McIlwain, R.; Young, S.; Hiley, S.; Craig, A. W.; Babak, T.

10.1101/2024.01.05.574245 — cancer biology — Posted on 2024-01-07

3813 A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

10.1101/2024.01.07.574538 — cancer biology — Posted on 2024-01-07

3814 ELViM: Understanding Molecular Energy Landscape

Viegas, R. G.; Martins, I. B. S.; Sanches, M. N.; Oliveira Junior, A. B.; de Camargo, J. B.; Paulovich, F. V.; Leite, V. B. P.

10.1101/2024.01.04.574173 — biophysics — Posted on 2024-01-07

3815 Interaction Between Yersinia pestis Ail Outer Membrane Protein and the C-Terminal Domain of Human Vitronectin

Vasseur, L.; Barbault, F.; MONARI, A.

10.1101/2024.01.07.574511 — biophysics — Posted on 2024-01-07

3816 System-level analysis of genes mutated in muscular dystrophies reveals a functional pattern associated with muscle weakness distribution

Ozisik, O.; Gorokhova, S.; Cerino, M.; Bartoli, M.; Baudot, A.

10.1101/2024.01.05.574331 — bioinformatics — Posted on 2024-01-07

3817 Spatial Morphoproteomic Features Predict Uniqueness of Immune Microarchitectures and Responses in Lymphoid Follicles

Hu, T.; Allam, M.; Kaushik, V.; Goudy, S. L.; Xu, Q.; Mudd, P.; Manthiram, K.; Coskun, A. F.

10.1101/2024.01.05.574186 — bioinformatics — Posted on 2024-01-07

3818 Detecting m6A RNA modification from nanopore sequencing using a semi-supervised learning framework

Teng, H.; Stoiber, M.; Bar-Joseph, Z.; Kingsford, C.

10.1101/2024.01.06.574484 — bioinformatics — Posted on 2024-01-07

3819 From Understudied to Understood: Multi-Omics Analysis with MiniENCODE Exemplified by Zebrafish

Yang, H.; Shan, Z.; Shang, H.; Jiang, P.; Li, Y.; Tu, Q.

10.1101/2024.01.06.573815 — genomics — Posted on 2024-01-07

3820 Tolerance thresholds underlie responses to DNA damage during germline development

Jansen, G.; Gebert, D.; Ravindra Kumar, T.; Simmons, E.; Murphy, S.; Karam Teixeira, F.

10.1101/2024.01.07.574510 — developmental biology — Posted on 2024-01-07

3821 Dynamic cytoophidia during Drosophila late oogenesis

Zhang, S.-Q.; Liu, J.-L.

10.1101/2024.01.06.574498 — developmental biology — Posted on 2024-01-07

3822 Analysis of the Borreliaceae Pangenome Reveals a Conserved Genomic Archictecture Across Phylogenetic Scales

Lemieux, J. E.

10.1101/2024.01.07.574540 — microbiology — Posted on 2024-01-07

3823 Small Intestinal Goblet Cells Control Humoral Immune Responses and Mobilization During Enteric Infection.

Kulkarni, D. H.; Talati, K. B.; Joyce, E. L.; Kousik, H.; Harris, D. L.; Floyd, A. N.; Vavrinyuk, V.; Barrios, B.; Udayan, S.; McDonald, K. G.; John, V.; Hsieh, C.-S.; Newberry, R. D.

10.1101/2024.01.06.573891 — immunology — Posted on 2024-01-07

3824 Turmeric shortens lifespan in houseflies

Laurie, S.; Ainslie, L.; Mitchell, S.; Morimoto, J.

10.1101/2024.01.07.574512 — zoology — Posted on 2024-01-07

3825 The value of livestock abortion surveillance in Tanzania: identifying disease priorities and informing interventions

10.1101/2024.01.07.574517 — zoology — Posted on 2024-01-07

3826 AXOLOTL: an accurate method for detecting aberrant gene expression in rare diseases using coexpression constraints

Leng, F.; Liu, Y.; Zhang, J.; Shen, Y.; Liu, X.; Wang, Y.; Xu, W.

10.1101/2024.01.07.574502 — bioinformatics — Posted on 2024-01-07

3827 Protein deuteration via algal amino acids to overcome proton back-exchange for fast-MAS solid-state NMR of large proteins

Aucharova, H.; Klein, A.; Medina Gomez, S.; Soeldner, B.; Vasa, S. K.; Linser, R.

10.1101/2024.01.07.574532 — biochemistry — Posted on 2024-01-07

3828 An adaptive numerical method for multi-cellular simulations of organ development and disease

Osborne, J. M.

10.1101/2024.01.06.574290 — developmental biology — Posted on 2024-01-07

3829 Psilocybin Promotes Cell-Type-Specific Changes in the Orbitofrontal Cortex Revealed by Single-Nucleus RNA-seq

Huang, Z.; Wei, X.; Wang, Y.; Tian, J.; Dong, J.; Liang, B.; Lu, L.; Zhang, W.

10.1101/2024.01.07.573163 — neuroscience — Posted on 2024-01-07

3830 HDAC inhibitor derivatives induce differentiation of leukemic cells through two distinct and separable mechanisms

Kumar, P.; Josa-Cullere, L.; Jackson, T. R.; Bataille, C. J. R.; Vyas, P.; Milne, T. A.; Russell, A. J.

10.1101/2024.01.06.572546 — pharmacology and toxicology — Posted on 2024-01-07

3831 Differential effects of multiplex and uniplex affiliative relationships on biomarkers of inflammation

Vandeleest, J. J.; Wooddell, L. J.; Nathman, A. C.; Beisner, B. A.; McCowan, B.

10.1101/2022.11.01.514247 — animal behavior and cognition — Posted on 2024-01-07

3832 Movements and habitat selection of a marsupial carnivore in a modified landscape

Jones, E. M.; Koch, A. J.; Pay, J. M.; Mann, D. F.; Jones, M. E.; Hamede, R. K.

10.1101/2023.03.05.531208 — ecology — Posted on 2024-01-07

3833 TLN468 changes the pattern of tRNA used to readthrough premature termination codons in CFTR

Karri, S.; Cornu, D.; Serot, C.; biri, L.; Hatton, A.; Pranke, I.; Sermet-Gaudelus, I.; Hinzpeter, A.; Bidou, L.; NAMY, O.

10.1101/2023.02.02.526440 — molecular biology — Posted on 2024-01-07

3834 Poly ADP-ribosylation regulates Arc expression and promotes adaptive stress-coping

Dahan, E.; Taub, T.; Pergamenchik, L.; Vovk, A.; Manier, J.; Avneri, R.; Lax, E.

10.1101/2023.09.26.558845 — neuroscience — Posted on 2024-01-07

3835 Targeting mosquito X-chromosomes reveals complex transmission dynamics of sex ratio distorting gene drives

Haber, D. A.; Arien, Y.; Lamdan, L. B.; Alcalay, Y.; Zecharia, C.; Krsticevic, F.; Yonah, E. S.; Avraham, R. D.; Krzywinska, E.; Krzywinski, J.; Marois, E.; Windbichler, N.; Papathanos, P. A.

10.1101/2023.08.20.554004 — synthetic biology — Posted on 2024-01-07

3836 Spotless: a reproducible pipeline for benchmarking cell type deconvolution in spatial transcriptomics

Sang-aram, C.; Browaeys, R.; Seurinck, R.; Saeys, Y.

10.1101/2023.03.22.533802 — bioinformatics — Posted on 2024-01-07

3837 Complementary approaches to dissect late leaf rust resistance in an interspecific raspberry population

Prado, M.; Silva, A. V. d.; Campos, G. R.; Borges, K. L. R.; Yassue, R. M.; Husein, G.; Akens, F. F.; Sposito, M. B.; Amorim, L.; Behrouzi, P.; Bustos-Korts, D.; Fritsche Neto, R.

10.1101/2024.01.04.574234 — genetics — Posted on 2024-01-07

Smith, I.; Scott, K.; Haibe-Kains, B.

10.1101/2022.01.24.477615 — bioinformatics — Posted on 2024-01-07

3839 The archerfish uses motor adaptation in shooting to correct for changing physical conditions

Volotsky, S.; Donchin, O.; Segev, R.

10.1101/2023.10.03.560658 — animal behavior and cognition — Posted on 2024-01-07

3840 The ICF2 gene Zbtb24 specifically regulates the differentiation of B1 cells via promoting heme synthesis

Wang, J.; Gao, H.; Zhao, S.; Dai, X.; Zheng, W.; Zhu, C.; Wang, H.; Zhu, X.; Gong, F.; Gao, X.; Zhao, Y.

10.1101/2023.12.23.573176 — immunology — Posted on 2024-01-07

3841 The neuron mixer and its impact on human brain dynamics

Luff, C.; Peach, R. L.; Mallas, E.-J.; Rhodes, E.; Laumann, F.; Boyden, E. S.; Sharp, D. J.; Barahona, M.; Grossman, N.

10.1101/2023.01.05.522833 — neuroscience — Posted on 2024-01-07

3842 A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma

Weiner, A. K.; Radaoui, A. B.; Tsang, M.; Martinez, D.; Sidoli, S.; Conkrite, K. L.; Delaidelli, A.; Modi, A.; Rokita, J. L.; Patel, K.; Lane, M. V.; Zhang, B.; Zhong, C.; Ennis, B.; Miller, D. P.; Brown, M. A.; Rathi, K. S.; Raman, P.; Pogoriler, J.; Bhatti, T.; Pawel, B.; Glisovic-Aplenc, T.; Teicher, B.; Erickson, S. W.; Earley, E. J.; Bosse, K. R.; Sorensen, P. H.; Krytska, K.; Mosse, Y. P.; Havenith, K. E.; Zammarchi, F.; van Berkel, P. H.; Smith, M. A.; Garcia, B. A.; Maris, J. M.; Diskin, S. J.

10.1101/2023.12.06.570390 — cancer biology — Posted on 2024-01-07

3843 Neural and behavioral dynamics of encoding, production and synchronization with external rhythms in subcortical lesion patients

Criscuolo, A.; Schwartze, M.; Nozaradan, S.; Kotz, S. A.

10.1101/2024.01.06.574472 — neuroscience — Posted on 2024-01-07

3844 Synaptic connectivity and electrophysiological properties of the nucleus of the lateral olfactory tract

Penker, S.; Lawabny, N.; Dhamshy, A.; Licht, T.; Rokni, D.

10.1101/2023.12.31.573522 — neuroscience — Posted on 2024-01-07

3845 Nascent RNA kinetics with complex promoter architecture: Analytic results and parameter inference

Shi, C.; Yang, X.; Zhou, T.; Zhang, J.

10.1101/2023.12.28.573588 — biophysics — Posted on 2024-01-07

3846 Spatial characterization of interface dermatitis in cutaneous lupus reveals novel chemokine ligand-receptor pairs that drive disease

Shakiba, S.; Haddadi, N.-S.; Afshari, K.; Lubov, J. E.; Raef, H. S.; Li, R.; Yildiz-Altay, U.; Daga, M.; Refat, M. A.; Kim, E.; Galindo de Laflin, J.; Akabane, A.; Sherman, S.; MacDonald, E.; Strassner, J. P.; Zhang, L.; Leon, M.; Baer, C. E.; Dresser, K.; Liang, Y.; Whitley, J. B.; Skopelja-Gardner, S.; Harris, J. E.; Deng, A.; Vesely, M. D.; Rashighi, M.; Richmond, J. M.

10.1101/2024.01.05.574422 — immunology — Posted on 2024-01-06

3847 Development of an optogenetic gene expression system in Lactococcus lactis using a split photoactivatable T7 RNA polymerase

Rodrigo-Navarro, A.; Salmeron-Sanchez, M.

10.1101/2024.01.05.574370 — synthetic biology — Posted on 2024-01-06

3848 Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide Agonists

Pawnikar, S.; Magenheimer, B. S.; Nevarez-Munoz, E.; Haldane, A.; Maser, R. L.; Miao, Y.

10.1101/2024.01.06.574465 — biochemistry — Posted on 2024-01-06

3849 Evidence for NR2F2/COUP-TFII involvement in human testis development

Wankanit, S.; Zidoune, H.; Bignon-Topalovic, J.; Schlick, L.; Houzelstein, D.; Fusee, L.; Boukri, A.; Nouri, N.; McElreavey, K.; Bashamboo, A.; Elzaiat, M.

10.1101/2024.01.05.574424 — molecular biology — Posted on 2024-01-06

3850 A universal molecular mechanism driving aging

Jin, W.; Zheng, J.; Xiao, Y.; Ju, L.; Chen, F.; Fu, J.; Jiang, H.; Zhang, Y.

10.1101/2024.01.06.574476 — molecular biology — Posted on 2024-01-06

3851 Rapid Emergence and Evolution of SARS-CoV-2 Variants in Advanced HIV Infection

Ko, S. H.; Radecki, P.; Belinky, F.; Bhiman, J.; Meiring, S.; Kleynhans, J.; Amoako, D.; Guerra Canedo, V.; Lucas, M.; Kekana, D.; Martinson, N.; Lebina, L.; Everatt, J.; Tempia, S.; Bylund, T.; Rawi, R.; Kwong, P.; Wolter, N.; von Gottberg, A.; Cohen, C.; Boritz, E. A.

10.1101/2024.01.05.574420 — microbiology — Posted on 2024-01-06

3852 Potential pandemic risk of circulating swine H1N2 influenza viruses

Le Sage, V.; Rockey, N. C.; McCarthy, K. R.; French, A. J.; Shephard, M. J.; McBride, R.; Jones, J. E.; Walter, S. G.; Doyle, J. D.; Xu, L.; Barbeau, D. J.; Wang, S.; Frizzell, S. A.; Rigatti, L. H.; Myerburg, M. M.; Paulson, J. C.; McElroy, A. K.; Anderson, T. K.; Vincent Baker, A. L.; Lakdawala, S. S.; Lakdawala, S. S.

10.1101/2024.01.05.574401 — microbiology — Posted on 2024-01-06

3853 Quantifying the daily harvest of fermentation products from the human gut microbiota

Arnoldini, M.; Sharma, R.; Moresi, C.; Chure, G.; Chabbey, J.; Slack, E.; Cremer, J.

10.1101/2024.01.05.573977 — microbiology — Posted on 2024-01-06

3854 A historical sequence deletion in a commonly used Bacillus subtilis chromosome integration vector generates undetected loss-of-function mutations

Dierksheide, K. J.; Li, G.-W.

10.1101/2024.01.04.574214 — microbiology — Posted on 2024-01-06

3855 Deletion of absent in melanoma (AIM) 2 gene alters bone morphology

Gong, Z.; Dixit, M.; Poudel, S. B.; Yildirim, G.; Yakar, S.; Muzumdar, R.

10.1101/2024.01.05.574199 — pathology — Posted on 2024-01-06

3856 Arf GTPase-activating protein ASAP1 specifically binds to 440-kD ankyrin-B

Li, Y.; Zhao, Y.; He, Y.; Zhang, M.; Chen, K.

10.1101/2024.01.05.574302 — biophysics — Posted on 2024-01-06

3857 Sequence clustering confounds AlphaFold2

Schafer, J. W.; Chakravarty, D.; Chen, E. A.; Porter, L.

10.1101/2024.01.05.574434 — bioinformatics — Posted on 2024-01-06

3858 A Survey of the Desulfuromonadia cytochromome provides a glimpse of the unexplored diversity of multiheme cytochromes in nature

Soares, R.; Fonseca, B. M.; Nash, B. W.; Paquete, C. M.; Louro, R. O.

10.1101/2024.01.05.574438 — biochemistry — Posted on 2024-01-06

3859 Contaminant Spot Check and Removal Assay (ContamSPOT) for Mass Spectrometry Analysis

Smeriglio, N.; Li, H.; binti Mazli, W. N. A.; Bendel, K. B.; Hao, L.

10.1101/2024.01.05.574392 — biochemistry — Posted on 2024-01-06

3860 Single cell proteomics by mass spectrometry reveals deep epigenetic insight and new targets of a class specific histone deacetylase inhibitor

Orsburn, B.

10.1101/2024.01.05.574437 — biochemistry — Posted on 2024-01-06

3861 Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells

Grenell, A. B.; Singh, C.; Raju, M.; Wolk, A.; Dalvi, S.; Jang, G.-F.; Crabb, J. S.; Hershberger, C. E.; Maniand, K.; Crabb, J. W.; Singh, R.; Du, J.; Anand-Apte, B.

10.1101/2024.01.05.574411 — biochemistry — Posted on 2024-01-06

3862 Swinging lever mechanism of myosin directly demonstrated by time-resolved cryoEM

Klebl, D. P.; McMillan, S. N.; Risi, C.; Forgacs, E.; Virok, B.; Atherton, J.; Stofella, M.; Winkelmann, D.; Sobott, F.; Galkin, V.; Knight, P. J.; Muench, S. P.; Scarff, C.; White, H. D.

10.1101/2024.01.05.574365 — biochemistry — Posted on 2024-01-06

3863 Blood-based targeted metabolipidomics reveals altered omega fatty acid-derived lipid mediators in relapsing-remitting multiple sclerosis patients

Zahoor, I.; Waters, J.; Ata, N.; Datta, I.; Pedersen, T.; Cerghet, M.; Poisson, L.; Markovic-Plese, S.; Rattan, R.; Taha, A. Y.; Newman, J. W.; Giri, S.

10.1101/2024.01.04.574253 — biochemistry — Posted on 2024-01-06

3864 CGRP inhibits SARS-CoV-2 infection of bronchial epithelial cells and its pulmonary levels correlate with viral clearance in critical COVID-19 patients

Barbosa Bomfim, C. C.; Genin, H.; Cottoignies-Callamarte, A.; Gallois-Montbrun, S.; Murigneux, E.; Sams, A.; Rozenberg, A. R.; Belouzard, S.; Dubuisson, J.; Kosminder, O.; Pene, F.; Terrier, B.; Bomsel, M.; Ganor, Y.

10.1101/2024.01.05.574360 — microbiology — Posted on 2024-01-06

3865 Leveraging engineered Pseudomonas putida minicells for bioconversion of organic acids into short-chain methyl ketones

Kozaeva, E.; Nieto-Dominguez, M.; Tang, K. K. Y.; Nikel, P. I.

10.1101/2024.01.06.574483 — synthetic biology — Posted on 2024-01-06

3866 Impact of perinatal maternal docosahexaenoic acid-containing phospholipid synthesis on offspring growth and neurological symptoms

Kanatani, A.; Hishikawa, D.; Nagata, K.; Hamano, F.; Nakano, K.; Okamura, T.; Shimizu, T.; Shindou, H.; Nagamatsu, T.; Yanagida, K.

10.1101/2024.01.06.574487 — biochemistry — Posted on 2024-01-06

3867 Mitonuclear interactions impact aerobic metabolism in hybrids and may explain mitonuclear discordance in young, naturally hybridizing bird lineages

McDiarmid, C. S.; Hooper, D. M.; Stier, A.; Griffith, S. C.

10.1101/2023.11.19.567741 — evolutionary biology — Posted on 2024-01-06

3868 Characterization of YlxR/Ssr1238, a conserved RNA binding protein in a model cyanobacterium

Hemm, L.; Miucci, A.; Riediger, M.; Tholen, S.; Georg, J.; Schilling, O.; Hess, W. R.

10.1101/2024.01.06.574455 — microbiology — Posted on 2024-01-06

3869 Negative allosteric modulation of cannabinoid CB1 receptor signaling suppresses opioid-mediated tolerance and withdrawal without blocking opioid antinociception

Iyer, V.; Saberi, S. A.; Pacheco, R.; Fender Sizemore, E.; Stockman, S.; Kulkarni, A.; Cantwell, L.; Thakur, G. A.; Hohmann, A. G.

10.1101/2024.01.06.574477 — neuroscience — Posted on 2024-01-06

3870 Behavioral screening of conserved RNA-binding proteins reveals CEY-1/YBX RNA-binding protein dysfunction leads to impairments in memory and cognition

Hayden, A. N.; Brandel, K. L.; Merlau, P. R.; Vijayakumar, P.; Leptich, E. J.; Pietryk, E. W.; Gaytan, E. S.; Ni, C. W.; Chao, H.-T.; Rosenfeld, J. A.; Arey, R. N.

10.1101/2024.01.05.574402 — neuroscience — Posted on 2024-01-06

3871 Graph Learning for Cortical Parcellation from Tensor Decompositions of Resting-State fMRI

Liu, Y.; Li, J.; Wisnowski, J. L.; Leahy, R. M.

10.1101/2024.01.05.574423 — neuroscience — Posted on 2024-01-06

3872 Visual image familiarity learning at multiple timescales in the primate inferotemporal cortex

Mohan, K.; Obilinovic, U. P.; Srednyak, S.; Amit, Y.; Brunel, N.; Freedman, D. J.

10.1101/2024.01.05.574412 — neuroscience — Posted on 2024-01-06

3873 Spontaneous activity of striatal projection neurons supports maturation of striatal inputs to substantia nigra dopaminergic neurons

Kokinovic, B.; Seja, P.; Donati, A.; Ryazantseva, M.; de Kerchove d'Exaerde, A.; Schiffmann, S. N.; Taira, T.; Molchanova, S. M.

10.1101/2024.01.05.574371 — neuroscience — Posted on 2024-01-06

3874 Increased extra-axial cerebrospinal fluid and benign external hydrocephalus in early autism

Ben-Arie, G.; Meiri, G.; Menashe, I.; Shelef, I.; Dinstein, I.; Arazi, A.

10.1101/2024.01.04.574160 — neuroscience — Posted on 2024-01-06

3875 Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction

Hoogstraaten, R. I.; Abramian, A.; Murphy, F. H.; mcDaniel, K. F.; Toonen, R. F.; Verhage, M.

10.1101/2024.01.05.574432 — neuroscience — Posted on 2024-01-06

3876 Auditory and visual gratings elicit distinct gamma responses

Gulati, D.; Ray, S.

10.1101/2024.01.05.574448 — neuroscience — Posted on 2024-01-06

3877 Light-based juxtacrine signaling between synthetic cells

Moghimianavval, H.; Loi, K. J.; Hwang, S.-W.; Bashirzadeh, Y.; Liu, A. P.

10.1101/2024.01.05.574425 — synthetic biology — Posted on 2024-01-06

3878 Invariant crossmodal equivalence between objects in rhesus monkeys

Cabrera-Ruiz, E.; Alva, M.; Mata, M.; Trevino, M.; Vergara, J.; Figueroa, T.; Perez-Orive, J.; Lemus, L.

10.1101/2024.01.05.574397 — animal behavior and cognition — Posted on 2024-01-06

3879 A Comparative Machine Learning Study of Connectivity-Based Biomarkers of Schizophrenia

Shevchenko, V.; Benn, R. A.; Scholz, R.; Wei, W.; Pallavicini, C.; Klatzmann, U.; Alberti, F.; Satterthwaite, T. D.; Wassermann, D.; Bazin, P.-L.; Margulies, D. S.

10.1101/2024.01.05.573898 — neuroscience — Posted on 2024-01-06

3880 Dynamic parallel transmit diffusion MRI at 7T

Zhang, M.; Ding, B.; Dragonu, I.; Liebig, P.; Rodgers, C. T.

10.1101/2024.01.06.574463 — neuroscience — Posted on 2024-01-06

3881 Molecular, physiological and functional features underlying cortical thinning related to antipsychotic medication use

Tuominen, L.; Armio, R.-L.; Hansen, J. Y.; Walta, M.; Koutsouleris, N.; Laurikainen, H.; Salokangas, R. K. R.; Misic, B.; Hietala, J.

10.1101/2024.01.05.573095 — neuroscience — Posted on 2024-01-06

3882 Stable Individual Differences from Dynamic Patterns of Function: Brain Network Flexibility Predicts Openness/Intellect and Intelligence

Sassenberg, T. A.; Safron, A.; DeYoung, C. G.

10.1101/2024.01.05.574386 — neuroscience — Posted on 2024-01-06

3883 The control of overt and covert attention across two nodes of the attention-control network

Polosecki, P.; Steenrod, S. C.; Stemmann, H.; Freiwald, W. A.

10.1101/2024.01.05.574406 — neuroscience — Posted on 2024-01-06

3884 Loss of the E3 ubiquitin ligase TRIM67alters the post-synaptic density proteome

McCormick, L. E.; Barker, N. K.; Herring, L. E.; Gupton, S. L.

10.1101/2024.01.05.574385 — neuroscience — Posted on 2024-01-06

3885 A Novel Mouse Model for LAMA2-Related Muscular Dystrophy: Analysis of Molecular Pathogenesis and Clinical Phenotype

Tan, D.; Liu, Y.; Luo, H.; Shen, Q.; Long, X.; Xu, L.; Liu, J.; Zhong, N.; Zhang, H.; Xiong, H.

10.1101/2024.01.06.574440 — neuroscience — Posted on 2024-01-06

3886 Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice

Ishchenko, Y.; Jeng, A. T.; Feng, S.; Nottoli, T.; Manriquez-Rodriguez, C.; Nguyen, K.; Carrizales, M. G.; Vitarelli, M. J.; Corcoran, E. E.; Greer, C. A.; Myers, S. A.; Koleske, A. J.

10.1101/2024.01.05.574442 — neuroscience — Posted on 2024-01-06

3887 Interpretable deep learning for deconvolutional analysis of neural signals

Tolooshams, B.; Matias, S.; Wu, H.; Temereanca, S.; Uchida, N.; Murthy, V. N.; Masset, P.; Ba, D.

10.1101/2024.01.05.574379 — neuroscience — Posted on 2024-01-06

3888 Information-based rhythmic transcranial magnetic stimulation accelerates learning during auditory working memory training.

Whittaker, H. T.; Khayyatt, L.; Fortier-Lavallee, J.; Belanger, C.; Laverdiere, M.; Zatorre, R. J.; Albouy, P.

10.1101/2024.01.05.572158 — neuroscience — Posted on 2024-01-06

3889 Neural interference between real and imagined visual stimuli

Sulfaro, A. A.; Robinson, A. A.; Carlson, T. A.

10.1101/2024.01.05.574285 — neuroscience — Posted on 2024-01-06

3890 A stable microtubule bundle formed through an orchestrated multistep process controls quiescence exit

Laporte, D.; Massoni-Laporte, A.; Lefranc, C.; Dompierre, J.; Mauboules, D.; Nsamba, E. T.; Royou, A.; Gal, L.; Schuldiner, M.; Gupta, M.; Sagot, I.

10.1101/2023.05.02.539064 — cell biology — Posted on 2024-01-06

3891 Tracking single cell evolution via clock-like chromatin accessibility

Xiao, Y.; Jin, W.; Ju, L.; Fu, J.; Wang, G.; Yu, M.; Chen, F.; Qian, K.; Wang, X.; Zhang, Y.

10.1101/2022.05.12.491736 — bioinformatics — Posted on 2024-01-06

3892 Correlative single-cell hard X-ray tomography and X-ray fluorescence imaging

Lin, Z.; Zhang, X.; Nandi, P.; Lin, Y.; Wang, L.; Chu, Y.; Paape, T.; Yang, Y.; Xiao, X.; Liu, Q.

10.1101/2023.08.03.551868 — cell biology — Posted on 2024-01-06

3893 A Causal Perspective for Batch Effects: When is no answer better than a wrong answer?

Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.

10.1101/2021.09.03.458920 — neuroscience — Posted on 2024-01-06

3894 Developmental remodeling repurposes larval neurons for sexual behaviors in adult Drosophila

Diamandi, J. A.; Duckhorn, J. C.; Miller, K. E.; Weinstock, M.; Leone, S.; Murphy, M. R.; Shirangi, T. R.

10.1101/2023.11.30.569472 — neuroscience — Posted on 2024-01-06

3895 Spotless: a reproducible pipeline for benchmarking cell type deconvolution in spatial transcriptomics

Sang-aram, C.; Browaeys, R.; Seurinck, R.; Saeys, Y.

10.1101/2023.03.22.533802 — bioinformatics — Posted on 2024-01-06

3896 Genomic Insights into the Population History and Adaptive Traits of Latin American Criollo Cattle

Ward, J. A.; Ng'ang'a, S. I.; Randhawa, I. A. S.; McHugo, G. P.; O'Grady, J. F.; Florez, J. M.; Browne, J. A.; Perez O'Brien, A. M.; Landaeta-Hernandez, A. J.; Garcia, J. F.; Sonstegard, T. S.; Frantz, L. A. F.; Salter-Townshend, M.; MacHugh, D. E.

10.1101/2023.09.10.556512 — genomics — Posted on 2024-01-06

3897 CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma

Cho, M. M.; Song, L.; Quamine, A. E.; Szewc, F.; Shi, L.; Erbe, A. K.; Ebben, J. D.; Turicek, D. P.; Kline, J. M.; Lafeber, E. O.; Phillips, M. F.; Ceas, A. S.; Capitini, C. M.

10.1101/2023.06.07.544144 — cancer biology — Posted on 2024-01-06

3898 ExploreTurns: A web tool for the exploration, analysis and retrieval of beta turns and their contexts in proteins; application to beta-bulge loops and helix capping

Newell, N. E.

10.1101/2024.01.01.573820 — bioinformatics — Posted on 2024-01-06

3899 The Septin Cytoskeleton is Required for Plasma Membrane Repair

Prislusky, M. I. A.; Lam, J. G.; Ruiz Contreras, V.; Ng, M.; Chamberlain, M.; Pathak-Sharma, S.; Fields, M.; Zhang, X.; Amer, A.; Seveau, S. M.

10.1101/2023.07.12.548547 — cell biology — Posted on 2024-01-06

3900 Transcription Coupled Repair of DNA Interstrand Crosslinks by UVSSA

Liebau, R. C.; Waters, C.; Ahmed, A.; Soni, R. K.; Gautier, J.

10.1101/2023.05.10.538304 — molecular biology — Posted on 2024-01-06

3901 The "motive cocktail" in altruistic behaviors

Wu, X.; Ren, X.; Liu, C.; Zhang, H.

10.1101/2023.08.20.554026 — neuroscience — Posted on 2024-01-06

3902 Retrieval of developmental social memories requires activation of the adult-born granule cell-CA2 circuit in mice

Laham, B. J.; Gore, I. R.; Brown, C. J.; Gould, E.

10.1101/2023.06.14.545015 — neuroscience — Posted on 2024-01-06

3903 A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle

Hernandez Hernandez, G.; O'Dwyer, S. C.; Matsumoto, C.; Tieu, M.; Fong, Z.; Yang, P.-C.; Lewis, T. J.; Santana, L. F.; Clancy, C. E.

10.1101/2023.06.24.546394 — physiology — Posted on 2024-01-06

3904 MapTurns: mapping the structure, H-bonding and contexts of beta turns in proteins

Newell, N. E.

10.1101/2024.01.02.573949 — bioinformatics — Posted on 2024-01-06

3905 CaMKIIalpha and CaMKIIbeta hub domains adopt distinct oligomeric states and stabilities

Ozden, C.; MacManus, S.; Adafia, R.; Samkutty, A.; Ocampo, A. T.; Garman, S. C.; Stratton, M. M.

10.1101/2023.10.09.561517 — biochemistry — Posted on 2024-01-06

3906 Comprehensive and accurate genome analysis at scale using DRAGEN accelerated algorithms

Behera, S.; Catreux, S.; Rossi, M.; Truong, S.; Huang, Z.; Ruehle, M.; Visvanath, A.; Parnaby, G.; Roddey, C.; Onuchic, V.; Cameron, D. L.; English, A.; Mehtalia, S.; Han, J.; Mehio, R.; Sedlazeck, F. J.

10.1101/2024.01.02.573821 — genomics — Posted on 2024-01-06

3907 ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

Thayer, M. J.; Heskett, M. B.; Smith, L. G.; Spellman, P. T.; Yates, P. A.

10.1101/2022.06.04.494840 — genetics — Posted on 2024-01-06

3908 Evolution of sex differences in cooperation:the role of trade-offs with dispersal

Capilla-Lasheras, P.; Bircher, N.; Brown, A.; Harrison, X.; Reed, T. E.; York, J.; Cram, D.; Rutz, C.; Walker, L.; Naguib, M.; Young, A.

10.1101/2023.09.13.557370 — evolutionary biology — Posted on 2024-01-06

3909 The 3-Dimensional Genome Drives the Evolution of Asymmetric Gene Duplicates via Enhancer Capture-Divergence

Lee, U.; Arsala, D.; Xia, S.; Li, C.; Ali, M.; Svetec, N.; Langer, C.; Sobreira, D.; Eres, I.; Sosa, D.; Chen, J.; Zhang, L.; Reilly, P.; Guzzetta, A.; Emerson, J. J.; Andolfatto, P.; Zhao, L.; Long, M.

10.1101/2022.11.30.518413 — evolutionary biology — Posted on 2024-01-06

3910 Soils-on-a-chip reveal unforeseen motility parameters of microconfined Bradyrhizobium diazoefficiens

Pires Monteiro, M.; Carrillo, J. P.; Gutierrez, N.; Montagna, S.; Lodeiro, A. R.; Cordero, M. L.; Marconi, V. I.

10.1101/2023.12.29.573673 — ecology — Posted on 2024-01-06

3911 Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

Jarysta, A.; Tadenev, A. L. D.; Day, M.; Krawchuk, B.; Low, B. E.; Wiles, M. V.; Tarchini, B.

10.1101/2023.05.25.542257 — developmental biology — Posted on 2024-01-06

3912 Cooperation between Nodal and FGF signals regulates zebrafish cardiac cell migration and heart morphogenesis

Gonzalez, V.; Grant, M. G.; Suzuki, M.; Christophers, B.; Williams, J. R.; Burdine, R. D.

10.1101/2024.01.05.574380 — developmental biology — Posted on 2024-01-06

3913 Optimisation of cell fate determination for cultured muscle differentiation

Melzener, L.; Schaeken, L.; Fros, M.; Messmer, T.; Raina, D.; Kiessling, A.; van Haaften, T.; Spaans, S.; Dogan, A.; Post, M. J.; Flack, J. E.

10.1101/2023.09.06.556523 — cell biology — Posted on 2024-01-06

3914 A geometric parameterization for beta turns

Newell, N. E.

10.1101/2024.01.01.573818 — molecular biology — Posted on 2024-01-06

3915 Effects of chronic exposure to fluoxetine, eicosapentaenoic acid, and lipopolysaccharide on behavior and hippocampal transcriptome in the rat model of prolonged chronic unpredictable stress

Demin, K. A.; Kolesnikova, T. O.; Galstyan, D. S.; Krotova, N. A.; Ilyin, N. P.; Derzhavina, K. A.; Seredinskaya, M.; Kositsyn, Y. M.; Sorokin, D. V.; Nerush, M. O.; Khaybaev, A.-A. S.; Pushkareva, S. A.; Strekalova, T.; Petersen, E. V.; de Abreu, M. S.; Masharsky, A.; Kalueff, A. V.

10.1101/2021.12.05.471274 — neuroscience — Posted on 2024-01-06

3916 Identifying behavioral links to neural dynamics of multifiber photometry recordings in a mouse social behavior network

Chen, Y.; Chien, J. M.; Dai, B.; Lin, D.; Chen, Z. S.

10.1101/2023.12.25.573308 — neuroscience — Posted on 2024-01-06

3917 Identifying Overlapping and Distinct Functional Brain Connectivity Profiles Associated with Cognitive Functioning in Children and Adolescents with ADHD

Pho, B.; Stevenson, R.; Mohsenzadeh, Y.; Stojanoski, B.

10.1101/2023.12.20.572617 — neuroscience — Posted on 2024-01-06

3918 Mediodorsal thalamus regulates sensory and mapping uncertainties in flexible decision making

Zhang, X.; Halassa, M. M.; Chen, Z. S.

10.1101/2022.12.11.519975 — neuroscience — Posted on 2024-01-06

3919 Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex

Schneider-Mizell, C. M.; Bodor, A.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Elabbady, L.; Kapner, D.; Kinn, S.; Mahalingam, G.; Seshamani, S.; Suckow, S.; Takeno, M.; Torres, R.; Yin, W.; Dorkenwald, S.; Bae, J. A.; Castro, M. A.; Fahey, P. G.; Froudarakis, E.; Halageri, A.; Jia, Z.; Jordan, C.; Kemnitz, N.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Papadopoulos, S.; Patel, S.; Pitkow, X.; Popovych, S.; Silversmith, W.; Sinz, F.; Turner, N. L.; Wong, W.; Wu, J.; Yu, S.-c.; MICrONs Consortium, ; Reimer, J.; Tolias, A.; Seung, H. S.; Reid, R.

10.1101/2023.01.23.525290 — neuroscience — Posted on 2024-01-06

3920 Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes

Atmaramani, R.; Dreossi, T.; Ford, K.; Gan, L.; Mitchell, J.; Tu, S.; Velayutham, J.; Zeng, H.; Soare, T.; Hari, M.; Hergenreder, E.; Redmond, S.; Bao, Y.; Yi, F.; Xu, D.; Conrad, R.; Mittal, N.; Akle, S.; Atkeson, N.; Liu, J.; Sivanandan, S.; Guo, S.-M.; Lam, E.; Sandakli, A.; Conrad, P.; Zhang, L.; Topol, A.; Chickering, M.; Hartley, B.; Karaletsos, T.; Krauel, E.-M.; Labow, M.; Hargreaves, R.; Trotter, M.; Biswas, S.; Pisco, A. O.; Kaykas, A.; Koller, D.; Sances, S.

10.1101/2024.01.04.574270 — neuroscience — Posted on 2024-01-06

3921 The mTOR pathway genes mTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function

Nguyen, L. H.; Xu, Y.; Nair, M.; Bordey, A.

10.1101/2023.08.11.553034 — neuroscience — Posted on 2024-01-06

3922 The unreasonable effectiveness of the total quasi-steady state approximation, and its limitations

Eilertsen, J.; Schnell, S.; Walcher, S.

10.1101/2023.09.28.559798 — systems biology — Posted on 2024-01-06

3923 Aerosolized α1 adrenoreceptor antagonism does not affect experimentally induced lung fibrosis in animal models

Ghincea, A.; Perry, C.; Liu, A.; McGovern, J.; Yu, S.; Peng, X. Y.; Genta, I.; Barnthaler, T.; Herzog, E.; Sun, H.

10.1101/2023.12.12.571378 — pathology — Posted on 2024-01-06

3924 The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

Li, L.; Cheng, S.; Yeh, Y.; Shi, Y.; Henderson, N.; Price, D.; Gu, X.; Yu, X.

10.1101/2023.09.27.559832 — cancer biology — Posted on 2024-01-06

3925 Joint estimation of paternity, sibships and pollen dispersal in a snapdragon hybrid zone

Ellis, T. J.; Field, D. L.; Barton, N. H.

10.1101/2024.01.05.574354 — evolutionary biology — Posted on 2024-01-05

3926 Genetically encoded Boolean logic operators to sense and integrate phenylpropanoid metabolite levels in plants

Ferreira, S. S.; Antunes, M. S.

10.1101/2024.01.05.574427 — plant biology — Posted on 2024-01-05

3927 Convergence and global epidemiology of Klebsiella pneumoniae plasmids harbouring the iuc3 virulence locus.

Gibbon, M. J.; Couto, N.; Cozens, K.; Habib, S.; Cowley, L.; Aanensen, D.; Corander, J.; Thorpe, H.; Hetland, M. A.; Sassera, D.; Merla, C.; Corbella, M.; Ferrari, C.; Turner, K. M.; Sirikancha, K.; Dulyayangkul, P.; Alhusein, N.; Charoenlap, N.; Thamlikitikul, V.; Avison, M. B.; Feil, E. J.

10.1101/2024.01.05.574329 — genomics — Posted on 2024-01-05

3928 Pathogen and host adapt pH responses during enteric infection

Woodward, S. E.; Neufeld, L. M. P.; Pena-Diaz, J.; Feng, W.; Serapio-Palacios, A.; Tarrant, I.; Finlay, B. B.

10.1101/2024.01.05.573998 — microbiology — Posted on 2024-01-05

3929 Temporal information of subsecond sensory stimuli in primary visual cortex is encoded via high dimensional population vectors.

Post, S.; Mol, W.; Rahmatullah, N.; Goel, A.

10.1101/2024.01.05.574126 — neuroscience — Posted on 2024-01-05

3930 Investigating the cis-Regulatory Basis of C3 and C4 Photosynthesis in Grasses at Single-Cell Resolution

Mendieta, J. P.; Tu, X.; Yan, H.; Zhang, X.; Marrand, A. P.; Zhong, S.; Schmitz, R. J.

10.1101/2024.01.05.574340 — plant biology — Posted on 2024-01-05

3931 ClonalTracker: a tool to elucidate dissemination patterns between vancomycin-resistant Enterococcus faecium isolates

Pascal Andreu, V.

10.1101/2024.01.05.574403 — bioinformatics — Posted on 2024-01-05

3932 Heparan sulfate selectively inhibits the collagenase activity of cathepsin K

Zhang, X.; Luo, Y.; Hao, H.; Krahn, J.; Su, G.; Dutcher, R.; Xu, Y.; Liu, J.; Pedersen, L. C.; Xu, D.

10.1101/2024.01.05.574350 — biochemistry — Posted on 2024-01-05

3933 Post-zygotic reproductive isolation is not correlated with chromosome number in plants.

Finch, G. S.; Yang, Y.; Barker, M. S.

10.1101/2024.01.05.573914 — evolutionary biology — Posted on 2024-01-05

3934 Antigen-display exosomes provide adjuvant-free protection against SARS-CoV-2 disease at nanogram levels of spike protein

Guo, C.; Sachithanandham, J.; Zhong, W.; Craney, M.; Villano, J.; Pekosz, A.; Gould, S.

10.1101/2024.01.04.574272 — bioengineering — Posted on 2024-01-05

3935 DNA-sequence and epigenomic determinants of local rates of transcription elongation

Liu, L.; Zhao, Y.; Siepel, A.

10.1101/2023.12.21.572932 — genomics — Posted on 2024-01-05

3936 The vitals for steady nucleation maps of spontaneous spiking coherence in autonomous two-dimensional neuronal networks

Zendrikov, D.; Paraskevov, A.

10.1101/2024.01.05.574396 — neuroscience — Posted on 2024-01-05

3937 Macrophages drive the earliest anti-tumoral response to BCG therapy by directly killing bladder cancer through TNF signaling

Martinez-Lopez, M.; de Almeida, C. R.; Fontes, M.; Mendes, R. V.; Kaufmann, S. H. E.; Fior, R.

10.1101/2024.01.05.574391 — cancer biology — Posted on 2024-01-05

3938 Resolving genotype-phenotype discrepancies of the Kidd blood group using nanopore sequencing

Gueuning, M.; Thun, G. A.; Schneider, L.; Trost, N.; Sigurdardottir, S.; Engström, C.; Rizzi, G.; Merki, Y.; Neuenschwander, K.; Frey, B. M.; Gassner, C.; Mattle-Greminger, M. P.; Meyer, S.

10.1101/2023.05.13.540649 — genetics — Posted on 2024-01-05

3939 Distinct positions of genetic and oral histories: Perspectives from India

Biddanda, A.; Bandyopadhyay, E.; de la Fuente Castro, C.; Witonsky, D.; Urban Aragon, J. A.; Pasupuleti, N.; Moots, H. M.; Fonseca, R.; Freilich, S.; Stanisavic, J.; Willis, T.; Menon, A.; Mustak, M. S.; Kodira, C. D.; Naren, A. P.; Sikdar, M.; Rai, N.; Raghavan, M.

10.1101/2022.07.06.498959 — genetics — Posted on 2024-01-05

3940 Maternal Care Leads to the Evolution of Long, Slow Lives

Zipple, M. N.; Reeve, H. K.; Peniston, J. H.

10.1101/2024.01.05.574353 — evolutionary biology — Posted on 2024-01-05

3941 Fish Blood Response to Ash-Induced Environmental Alkalinization, and their Implications to Wildfire-Scarred Watersheds

Kwan, G. T.; Sanders, T.; Huang, S.; Kilaghbian, K.; Sam, C.; Wang, J.; Weihrauch, K.; Wilson, R. W.; Fangue, N. A.

10.1101/2024.01.05.574400 — physiology — Posted on 2024-01-05

3942 Human cell surface-AAV interactomes identify LRP6 as blood-brain-barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder

Shay, T. F.; Jang, S.; Chen, X.; Walker, B.; Tebbutt, C.; Wolfe, D. A.; Brittain, T. J.; Arokiaraj, C. M.; Sullivan, E. E.; Ding, X.; Wang, T.-Y.; Lei, Y.; Chuapoco, M. R.; Chou, T.-F.; Gradinaru, V.

10.1101/2024.01.05.574399 — bioengineering — Posted on 2024-01-05

3943 Step selection analysis with non-linear and random effects in mgcv

Klappstein, N. J.; Michelot, T.; Fieberg, J.; Pedersen, E. J.; Field, C.; Mills Flemming, J.

10.1101/2024.01.05.574363 — ecology — Posted on 2024-01-05

3944 Cardiac stress leads to regulation of Filamin C dimerisation via an ancient phosphorylation-modulated interaction with HSPB7

Wang, Z.; Cao, G.; Collier, M. P.; Qiu, X.; Broadway-Stringer, S.; Saman, D.; NG, J. Z.; Sen, N.; Azad, A. J.; Hooper, C.; Zimmermann, J.; McDonough, M.; Brem, J.; Rabe, P.; Song, H.; Alderson, T. R.; Schofield, C. J.; Bolla, J. R.; Djinnovic-Carugo, K.; Fuerst, D.; Warscheid, B.; Degiacomi, M. T.; Allison, T. M.; Hochberg, G. K.; Robinson, C. V.; Gehmlich, K.; Benesch, J. L.

10.1101/2024.01.05.574393 — molecular biology — Posted on 2024-01-05

3945 Surface colonization by Flavobacterium johnsoniae promotes its survival in a model microbial community

Magesh, S.; Hurley, A.; Nepper, J.; Chevrette, M.; Schrope, J. H.; Li, C.; Beebe, D. J.; Handelsman, J.

10.1101/2024.01.05.574367 — microbiology — Posted on 2024-01-05

3946 The Primary Function of MTL is Memory, not Navigation: Grid Cells are Non-spatial (what) and Place Cells are Memories (what and where) that Cause Grid Fields through Retrieval

Huber, D. E.

10.1101/2023.12.30.573694 — neuroscience — Posted on 2024-01-05

3947 Selective recruitment: Evidence for task-dependent gating of inputs to the cerebellum

Shahshahani, L.; King, M.; Nettekoven, C.; Ivry, R.; Diedrichsen, J.

10.1101/2023.01.25.525395 — neuroscience — Posted on 2024-01-05

3948 The volitional control of individual motor units is constrained within low-dimensional manifolds by common inputs

Rossato, J.; Avrillon, S.; Tucker, K.; Farina, D.; Hug, F.

10.1101/2024.01.05.573816 — neuroscience — Posted on 2024-01-05

3949 MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomography

Lamm, L.; Zufferey, S.; Righetto, R. D.; Wietrzynski, W.; Yamauchi, K. A.; Burt, A.; Liu, Y.; Zhang, H.; Martinez-Sanchez, A.; Ziegler, S.; Isensee, F.; Schnabel, J. A.; Engel, B. D.; Peng, T.

10.1101/2024.01.05.574336 — bioinformatics — Posted on 2024-01-05

3950 A suicidal and extensively disordered luciferase with a bright luminescence

Dijkema, F. M.; Escarpizo-Lorenzana, M. I.; Nordentoft, M. K.; Rabe, H. C.; Sahin, C.; Landreh, M.; Branca, R. M.; Sorensen, E. S.; Christensen, B. S.; Prestel, A.; Teilum, K.; Winther, J. R.

10.1101/2023.12.21.572513 — biochemistry — Posted on 2024-01-05

3951 Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models

Uechi, H.; Sridharan, S.; Nijssen, J.; Bilstein, J.; Iglesias-Artola, J. M.; Kishigami, S.; Casablancas-Antras, V.; Poser, I.; Martinez, E. J.; Boczek, E.; Wagner, M.; Tomschke, N.; de Jesus Domingues, A. M.; Pal, A.; Doeleman, T.; Kour, S.; Anderson, E. N.; Stein, F.; Lee, H. O.; Zhang, X.; Fritsch, A. W.; Jahnel, M.; Fursch, J.; Murthy, A. C.; Alberti, S.; Bickle, M.; Fawzi, N. L.; Nadler, A.; David, D. C.; Pandey, U. B.; Hermann, A.; Stengel, F.; Davis, B. G.; Baldwin, A. J.; Savitski, M. M.; Hyman, A. A.; Wheeler, R. J.

10.1101/721001 — cell biology — Posted on 2024-01-05

3952 SanA is an inner membrane protein mediating the early stages of Salmonella infection

Aleksandrowicz, A.; Kolenda, R.; Thurston, T. L. M.; Grzymajlo, K.

10.1101/2024.01.05.574334 — microbiology — Posted on 2024-01-05

3953 Wild bird mass mortalities in eastern Canada associated with the Highly Pathogenic Avian Influenza A(H5N1) virus, 2022

Avery-Gomm, S.; Barychka, T.; English, M.; Ronconi, R.; Wilhelm, S. I.; Rail, J.-F.; Cormier, T.; Beaumont, M.; Bowser, C.; Burt, T. V.; Collins, S.; Duffy, S.; Giacinti, J. A.; Gilliland, S.; Giroux, J.-F.; Gjerdrum, C.; Guillemette, M.; Hargan, K. E.; Jones, M.; Kennedy, A.; Kusalik, L.; Lair, S.; Lang, A. S.; Lavoie, R. A.; Lepage, C.; McPhail, G.; Montevecchi, W. A.; Parsons, G. J.; Provencher, J. F.; Rahman, I.; Robertson, G. J.; Seyer, Y.; Soos, C.; Ward, C. R. E.; Wells, R.; Wight, J.

10.1101/2024.01.05.574233 — zoology — Posted on 2024-01-05

3954 CREB activation drives acinar to ductal reprogramming and promote pancreatic cancer progression in animal models of alcoholic chronic pancreatitis

Srinivasan, S.; Mehra, S.; Bianchi, A.; Singh, S.; Dosch, A. R.; Amirian, H.; Jinka, S.; Krishnamoorthy, V.; Silva, I. D. C.; Box, E. W.; Garrido, V.; Totiger, T. M.; Zhou, Z.; Ban, Y.; Datta, J.; VanSaun, M.; Merchant, N.; Nagathihalli, N.

10.1101/2024.01.05.574376 — cancer biology — Posted on 2024-01-05

3955 Implication of structural constrains facilitating the functional evolution of Pseudomonas aeruginosa KPR2 into a versatile α-keto acid reductase.

Basu Choudhury, G.; Datta, S.

10.1101/2024.01.05.573888 — biochemistry — Posted on 2024-01-05

3956 Cooperation between Nodal and FGF signals regulates zebrafish cardiac cell migration and heart morphogenesis

Gonzalez, V.; Grant, M. G.; Suzuki, M.; Christophers, B.; Williams, J. R.; Burdine, R. D.

10.1101/2024.01.05.574380 — developmental biology — Posted on 2024-01-05

3957 Characterization of a Unique Spontaneous Calcifying Cell Line (CJ): a Novel Tool for the Study of Ectopic Calcification

Ida, N.; Yamane, Y.

10.1101/2024.01.05.574307 — cell biology — Posted on 2024-01-05

3958 A limited concentration range of diaphorin, a polyketide produced by a bacterial symbiont of the Asian citrus psyllid, promotes the in vitro gene expression with bacterial ribosomes

Takasu, R.; Izu, T.; Nakabachi, A.

10.1101/2024.01.05.574368 — microbiology — Posted on 2024-01-05

3959 Identification and validation of ITS2-specific universal primers for DNA barcoding in plants.

Bhat, A. R.; Hegde, S.; Kammar, S. S.; Muthamma, M. B.; Mudgal, G.; Mohan, T. C.; R, C.

10.1101/2024.01.05.574284 — plant biology — Posted on 2024-01-05

3960 Hormetic effect induced by Beauveria bassiana in Myzus persicae

Arinanto, L. S.; Hoffmann, A. A.; Ross, P. A.; Gu, X.

10.1101/2024.01.04.574279 — ecology — Posted on 2024-01-05

3961 Timely lagging strand maturation relies on Ubp10-mediated PCNA dissociation from replicating chromatin

Zamarreno, J.; Munoz, S.; Alonso, E.; Alcala, M.; Bermejo, R.; Sacristan, M. P.; Bueno, A.

10.1101/2024.01.05.574312 — molecular biology — Posted on 2024-01-05

3962 Phenylketonuria: modelling cerebral amino acid and neurotransmitter metabolism

Wegrzyn, A. B.; van Vliet, D.; van Eunen, K.; Heiner-Fokkema, M. R.; van der Zee, E. A.; van Spronsen, F.; Bakker, B. M.

10.1101/2024.01.05.574352 — systems biology — Posted on 2024-01-05

3963 High-resolution metabolite imaging: luteolinidin accumulates at the host-cyanobiont interface during cold-acclimation in Azolla symbioses

Güngör, E.; Bartels, B.; Bolchi, G.; Heeren, R. M. A.; Ellis, S.; Schluepmann, H.

10.1101/2024.01.05.574342 — plant biology — Posted on 2024-01-05

3964 A weighted and cumulative point system for accurate scoring of intestinal pathology in a piglet model of necrotizing enterocolitis

Offersen, S. M.; Henriksen, N. L.; Brunse, A.

10.1101/2024.01.05.574327 — pathology — Posted on 2024-01-05

3965 NBBC: Quantifying the Prevalence of Non-B DNA Motifs as a Marker of Non-B Burden in Cancer

Xu, Q.; Kowalski, J.

10.1101/2024.01.04.574106 — cancer biology — Posted on 2024-01-05

3966 Non-B DNA-Informed Mutation Burden as a Marker of Treatment Response and Outcome in Cancer

Xu, Q.; Kowalski, J.

10.1101/2024.01.04.574248 — cancer biology — Posted on 2024-01-05

3967 Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells

10.1101/2024.01.04.574237 — cancer biology — Posted on 2024-01-05

3968 A polymer physics view of peripheral chromatin: de Gennes' self-similar carpet

Erbas, A.; Sariyer, O. S.

10.1101/2024.01.05.574343 — biophysics — Posted on 2024-01-05

3969 MoCoLo: a testing framework for motif co-localization

Xu, Q.; del Mundo, I. M. A. d.; Zewail-Foote, M.; Luke, B.; Vasquez, K. M.; Kowalski, J.

10.1101/2024.01.04.574249 — bioinformatics — Posted on 2024-01-05

3970 Protein superfolds are characterised as frustration-free topologies: A case study of pure parallel beta-sheet topologies

Murata, H.; Toko, K.; Chikenji, G.

10.1101/2024.01.05.574326 — bioinformatics — Posted on 2024-01-05

3971 In-silico evaluation of Mirror repeats in some selected genes ofCandida albicans

Sehrawat, B.; Yadav, P.; Sarjeet, M.; Yadav, S.; Yadav, V.; Goyal, N.; Alam, P.; Ahlawat, M.; Yadav, S.

10.1101/2024.01.05.574287 — bioinformatics — Posted on 2024-01-05

3972 Bio-electricity production from Fibroblasts and their cultivation media.

Shlosberg, Y.; Lesman, A.

10.1101/2024.01.04.574251 — bioengineering — Posted on 2024-01-05

3973 Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment

Tarau, D.; Grunberger, F.; Pilsl, M.; Reichelt, R.; Heiss, F.; Konig, S.; Urlaub, H.; Hausner, W.; Engel, C.; Grohmann, D.

10.1101/2024.01.05.574147 — biochemistry — Posted on 2024-01-05

3974 Uncovering the Elusive Structures and Mechanisms of Prevalent Antidepressants

Lin, J.; Bu, G.; Unge, J.; Gonen, T.

10.1101/2024.01.04.574265 — biochemistry — Posted on 2024-01-05

3975 A complex mechanism translating variation of a simple genetic architecture into alternative life-histories

Verta, J.-P.; Moustakas-Verho, J.; Donner, I.; Frapin, M.; Ruokolainen, A.; Debes, P. V.; Erkinaro, J.; Primmer, C. R.

10.1101/2024.01.05.574286 — evolutionary biology — Posted on 2024-01-05

3976 In vitro determination of osteo-adipogenic lineage choice of bone marrow stromal/stem cells (BMSCs)

Qiu, D.; Wei, W.; Chen, J.; Huang, J.; Yang, Y.; Luo, Z.

10.1101/2024.01.05.574292 — cell biology — Posted on 2024-01-05

3977 Endocrine disruptor-induced epimutagenesis in vitro: Insight into molecular mechanisms

Lehle, J. D.; Lin, Y.-H.; Gomez, A.; Chavez, L.; McCarrey, J. R.

10.1101/2024.01.05.574355 — molecular biology — Posted on 2024-01-05

3978 CRISPR-repressed toxin-antitoxin provides population-level immunity against diverse anti-CRISPR elements

Li, M.; shu, x.; Wang, R.; Li, Z.; Xue, Q.; Liu, C.; Cheng, F.; Zhao, H.; Wang, J.; Liu, J.; Hu, C.; Li, J.; Ouyang, S.

10.1101/2024.01.05.574328 — microbiology — Posted on 2024-01-05

3979 Epstein-Barr Virus BALF0/1 Subverts the Caveolin and ERAD Pathways to Target B-cell Receptor Complexes for Degradation

Yiu, S. P. T.; Weekes, M. P.; Gewurz, B. E.

10.1101/2024.01.04.574276 — microbiology — Posted on 2024-01-05

3980 The CD4 T cell epigenetic JUNB+ state is associated with proliferation and exhaustion

Mihai, I. S.; Selinger, M.; Boucheron, N.; Forsell, M. N.; Magalhaes, I.; Trygg, J.; Henriksson, J.

10.1101/2024.01.05.573875 — immunology — Posted on 2024-01-05

3981 E protein control of NKgammadeltaT cell development through both generation and function of the stereotypic Vgamma1Vdelta6.3 TCR

Wiest, D. L.; Mihai, A.; Lee, S.-Y.; Shinton, S.; Parker, M. I.; Contreras, A. V.; Zhang, B.; Rhodes, M.; Dunbrack, R. L.; Zuniga-Pflucker, J. C.; Ciofani, M.; Zhuang, Y.

10.1101/2024.01.04.574274 — immunology — Posted on 2024-01-05

3982 Neural representations of predicted events: Evidence from time-resolved EEG decoding

Li, A.-S.; Theeuwes, J.; van Moorselaar, D.

10.1101/2024.01.05.574347 — neuroscience — Posted on 2024-01-05

3983 Distribution of calbindin-positive neurons across areas and layers of the marmoset cerebral cortex

Atapour, N.; Rosa, M. G. P.; Bai, S.; Bednarek, S.; Kulesza, A.; Saworska, G.; Worthy, K. H.; Majka, P.

10.1101/2024.01.05.574341 — neuroscience — Posted on 2024-01-05

3984 Pathogen infection induces sickness behaviors by recruiting neuromodulatory systems linked to stress and satiety in C. elegans

Pradhan, S.; Madan, G. K.; Kang, D.; Bueno, E.; Atanas, A. A.; Kramer, T. S.; Dag, U.; Lage, J. D.; Gomes, M. A.; Lu, A. K.-Y.; Park, J.; Flavell, S. W.

10.1101/2024.01.05.574345 — neuroscience — Posted on 2024-01-05

3985 The origin, deployment, and evolution of a plant-parasitic nematode effectorome

Molloy, B.; Shin, D. S.; Long, J.; Pellegrin, C.; Senatori, B.; Vieira, P.; Thorpe, P. J.; Damm, A.; Ahmad, M.; Vermeulen, K.; Derevnina, L.; Wei, S.; Sperling, A.; Reyes Estevez, E.; Bruty, S.; de Souza, V. H. M.; Kranse, O. P.; Maier, T.; Baum, T.; Eves-van den Akker, S.

10.1101/2024.01.05.574317 — plant biology — Posted on 2024-01-05

3986 Distinct causes underlie double-peaked trilobite morphological disparity

Drage, H. B.; Pates, S.

10.1101/2024.01.05.574297 — paleontology — Posted on 2024-01-05

3987 A Combinatorial Strategy for HRV 3C Protease Engineering to Achieve the N-terminal Free Cleavage

Yi, L.; Zhang, G.; Mei, M.; Fan, X.; Zhou, Y.; Zhang, F.

10.1101/2024.01.05.574269 — bioengineering — Posted on 2024-01-05

3988 Detailed mechanisms for unintended large DNA deletions with CRISPR, base editors, and prime editors

Hwang, G.-h.; Kim, S.-H.; Oh, M.; Kim, S.; Habib, O.; Jang, H.-K.; Kim, H. S.; Kim, C. H.; Kim, S.; Bae, S.

10.1101/2024.01.04.574288 — genetics — Posted on 2024-01-05

3989 Retention of an endosymbiont for the production of a single molecule

Garber, A.; Garcia de la Filia Molina, A.; Vea, I. M.; Mongue, A. J.; Ross, L.; McCutcheon, J. P.

10.1101/2024.01.04.574232 — evolutionary biology — Posted on 2024-01-05

3990 The recombination landscape of introgression in yeast

Schwarzkopf, E. J.; Brandt, N.; Smukowski Heil, C.

10.1101/2024.01.04.574263 — evolutionary biology — Posted on 2024-01-05

3991 Movement-integrated habitat selection reveals wolves balance ease of travel with human avoidance in a risk-reward trade-off

Kingdon, K. A.; Prokopenko, C. M.; Dupont, D. L.; Turner, J. W.; Weins, J.; Harriman, V. B.; Vander Wal, E.

10.1101/2024.01.04.574266 — ecology — Posted on 2024-01-05

3992 Epithelial cytokeratin 6a restricts secretory autophagy of proinflammatory cytokines by interacting with Sec16A

Bhushan, A.; Chan, J. K.; Sun, Y.; Ghiamati, F.; Crabb, J. S.; Jang, G.-F.; Willard, B.; Crabb, J. W.; Tam, C.

10.1101/2024.01.04.574264 — cell biology — Posted on 2024-01-05

3993 Novel Pentafluorosulfanyl-containing Triclocarban Analogs selectively kill Gram-positive bacteria.

Pormohammad, A.; Moradi, M.; Hommes, J. W.; Pujol, E.; Naesens, L. M. J.; Vazquez, S.; Surewaard, B. G.; Zarei, M.; Vazquez-Carrera, M.; Turner, R. J.

10.1101/2024.01.04.574235 — microbiology — Posted on 2024-01-05

3994 Identification of essential genes that support fitness of Acinetobacter baumannii efflux pump overproducers in the presence of fluoroquinolone

Hamami, E.; Huo, W.; Neal, K.; Neisewander, I.; Geisinger, E.; Isberg, R. R.

10.1101/2024.01.04.574119 — microbiology — Posted on 2024-01-05

3995 Large DNA viruses in early diverging fungal genomes are relics of past and present infections

Myers, J.; Schulz, F.; Rahimlou, S.; Amses, K.; Simmons, D. R.; Stajich, J. E.; James, T.

10.1101/2024.01.04.574182 — microbiology — Posted on 2024-01-05

3996 Sensory neurons regulate stimulus-dependent humoral immunity

Aguilar, D.; Zhu, F.; Millet, A.; Millet, N.; Germano, P.; Pisegna, J.; Doherty, T. A.; Swidergall, M.; Jendzjowsky, N.

10.1101/2024.01.04.574231 — immunology — Posted on 2024-01-05

3997 Longitudinal transcriptional changes reveal genes from the natural killer cell-mediated cytotoxicity pathway as critical players underlying COVID-19 progression

Medina, M. A.; Fuentes-Villalobos, F.; Quevedo, C.; Aguilera, F.; Riquelme, R.; Rioseco, M. L.; Barria, S.; Pinos, Y.; Calvo, M.; Burbulis, I.; Alvarez, R. A.; Garrido, J. L.; Barria, M. I.

10.1101/2024.01.02.573936 — immunology — Posted on 2024-01-05

3998 Disease-associated astrocyte epigenetic memory promotes CNS pathology

Lee, H.-G.; Rone, J. M.; Li, Z.; Faust Akl, C.; Shin, S. W.; Lee, J.-H.; Flausino, L. E.; Pernin, F.; Chao, C.-C.; Kleemann, K. L.; Srun, L.; Illouz, T.; Giovannoni, F.; Charabati, M.; Sanmarco, L. M.; Kenison, J. E.; Piester, G.; Zandee, S. E. J.; Antel, J.; Rothhammer, V.; Wheeler, M. A.; Prat, A.; Clark, I. C.; Quintana, F. J.

10.1101/2024.01.04.574196 — immunology — Posted on 2024-01-05

3999 Interferon Regulatory Factor 6 Determines Intestinal Epithelial Cell Development and Immunity

Wright, A. P.; Harris, S.; Madden, S. R.; Ramirez Reyes, B.; Mulamula, E.; Gibson, A. R.; Rauch, I.; Constant, D. A.; Nice, T. J.

10.1101/2024.01.04.574257 — immunology — Posted on 2024-01-05

4000 Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes

10.1101/2024.01.04.574270 — neuroscience — Posted on 2024-01-05

4001 Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects

Matos Santana, M.; Silva, P.; Pinto, M. M.; Gaspar, L.; Nobre, R. J.; Duarte, S.; Marques, T.; Gama-Carvalho, M.; Januario, C.; Cunha, I.; Ribeiro, J.; Huebener-Schmid, J.; Infante, J.; Raposo, M.; Lima, M.; Garcia-Moreno, H.; Giunti, P.; van de Warrenburg, B.; Synofzik, M.; Faber, J.; Klockgether, T.; ESMI Study Group, ; Pereira de Almeida, L.

10.1101/2024.01.04.574044 — neuroscience — Posted on 2024-01-05

4002 Efficient value encoding through convergence of tactile and visual value information in the primate putamen

Hwang, S.-H.; Lee, J.-W.; Park, D.; Lee, S.-H.; Kim, H. F.

10.1101/2024.01.04.574258 — neuroscience — Posted on 2024-01-05

4003 An ecological investigation of the effect of background noise on speech processing in a Virtual Classroom

Levy, O.; Korisky, A.; Zvilichovsky, Y.; Zion Golumbic, E.

10.1101/2024.01.05.574300 — neuroscience — Posted on 2024-01-05

4004 Developmental Reprogramming of Hypothalamic-Pituitary Axis in Mice by Common Environmental Pollutants

Mogus, J. P.; Marin, M.; Arowolo, O.; Salemme, V. R.; Suvorov, A.

10.1101/2024.01.04.574224 — pharmacology and toxicology — Posted on 2024-01-05

4005 PEMPS: A Phylogenetic Software Tool to Model the Evolution of Metabolic Pathways

McCloskey, N.; Mammedova, A.; Liberles, D. A.

10.1101/2024.01.04.574206 — bioinformatics — Posted on 2024-01-05

4006 MicroED structure of the C11 cysteine protease Clostripain

Ruma, Y. N.; Bu, G.; Gonen, T.

10.1101/2024.01.04.574240 — biochemistry — Posted on 2024-01-05

4007 Reconstructing fresh green leaf spectra in the SWIR-2 region (2001-2500 nm) collected in a humid environment by referring to publicly available green leaf spectral databases

Denaro, L. G.; Li, H.-J.; Chong, J.-Y.; Huang, C.-y.

10.1101/2024.01.04.574267 — biochemistry — Posted on 2024-01-05

4008 Unraveling the genetic legacy of commercial whaling in bowhead whales and narwhals

de Greef, E.; Müller, C.; Thorstensen, M. J.; Ferguson, S. H.; Watt, C. A.; Marcoux, M.; Petersen, S. D.; Garroway, C. J.

10.1101/2024.01.04.574243 — genomics — Posted on 2024-01-05

4009 Molecular Characterization of Tephromela atra and Tephromela grumosa from Bozdag Mountain Based on ITS1 rDNA Sequences Analysis

ALZEBAIR, A.; YILMAZ CANKILIC, M.; CANDAN, M.; AVAN, I.

10.1101/2024.01.04.574211 — evolutionary biology — Posted on 2024-01-05

4010 Quantitative species delimitation, tests for gene flow, and migration models uncover complex, recent speciation in tree squirrels

Abreu, E. F.; Prado, J. R.; Maldonado, J. E.; Wilson, D. E.; Percequillo, A. R.; Pavan, S. E.

10.1101/2024.01.04.574244 — evolutionary biology — Posted on 2024-01-05

4011 Global spatial potential for implementing land-based climate mitigation

Beaury, E. M.; Smith, J.; Levine, J.

10.1101/2024.01.04.574063 — ecology — Posted on 2024-01-05

4012 Microvilli regulate the release modes of alpha-tectorin to organize the domain-specific matrix architecture of the tectorial membrane.

Niazi, A.; Kim, J. A.; Kim, D.-K.; Lu, D.; Sterin, I.; Park, J.; Park, S.

10.1101/2024.01.04.574255 — developmental biology — Posted on 2024-01-05

4013 Morphological deficits of glial cells in a transgenic mouse model for developmental stuttering

Adeck, A.; Millwater, M.; Bragg, C.; Zhang, R.; SheikhBahaei, S.

10.1101/2024.01.04.574051 — cell biology — Posted on 2024-01-05

4014 Differential endothelial cell cycle status in postnatal retinal vessels revealed using a novel PIP-FUCCI reporter and zonation analysis

Liu, Z.; Tanke, N.; Neal, A.; Yu, T.; Branch, T.; Cook, J. G.; Bautch, V. L.

10.1101/2024.01.04.574239 — cell biology — Posted on 2024-01-05

4015 Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins

Ballmer, D.; Carter, W.; van Hooff, J. J. E.; Tromer, E. C.; Ishii, M.; Ludzia, P.; Akiyoshi, B.

10.1101/2024.01.04.574194 — cell biology — Posted on 2024-01-05

4016 Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies

King, L. D. W.; Pulido, D.; Barrett, J. R.; Davies, H.; Quinkert, D.; Lias, A. M.; Silk, S. E.; Pattinson, D. J.; Diouf, A.; Williams, B. G.; McHugh, K.; Rodrigues, A.; Rigby, C. A.; Strazza, V.; Suurbaar, J.; Rees-Spear, C.; Dabbs, R. A.; Ishizuka, A. S.; Zhou, Y.; Gupta, G.; Jin, J.; Li, Y.; Carnrot, C.; Minassian, A. M.; Campeotto, I.; Fleishman, S. J.; Noe, A. R.; MacGill, R. S.; King, C. R.; Birkett, A. J.; Soisson, L. A.; Long, C. A.; Miura, K.; Ashfield, R.; Skinner, K.; Howarth, M.; Biswas, S.; Draper, S. J.

10.1101/2024.01.04.574181 — immunology — Posted on 2024-01-05

4017 Multi-parametric assays capture sex- and environment-dependent modifiers of behavioral phenotypes in autism mouse models

Wahl, L.; Karim, A.; Hassett, A. R.; van der Doe, M.; Badura, A.

10.1101/2024.01.04.574201 — neuroscience — Posted on 2024-01-05

4018 Assessing White Matter Engagement in Brain Networks through Functional and Structural Connectivity Mapping

Li, M.; Schilling, K. G.; Ding, Z.; Gore, J. C.

10.1101/2024.01.04.574259 — neuroscience — Posted on 2024-01-05

4019 Microglia promote extracellular matrix deposition and restrict excitatory synapse numbers in the mesolimbic dopamine system during healthy aging

Gray, D. T.; Guitierrez, A.; Jami-Alahmadi, Y.; Pandey, V.; Pan, L.; Zhang, Y. T.; Wohlschlegel, J. A.; De Biase, L. M.

10.1101/2024.01.04.574215 — neuroscience — Posted on 2024-01-05

4020 Biophysical carbon concentrating mechanisms in land plants: insights from reaction-diffusion modeling

Kaste, J. A. M.; Walker, B. J.; Shachar-Hill, Y.

10.1101/2024.01.04.574220 — plant biology — Posted on 2024-01-05

4021 Live-cell imaging under centrifugation characterized the cellular force for nuclear centration in the Caenorhabditis elegans embryo

Goda, M.; Shribak, M.; Ikeda, Z.; Okada, N.; Tani, T.; Goshima, G.; Oldenbourg, R.; Kimura, A.

10.1101/2024.01.03.574024 — biophysics — Posted on 2024-01-05

4022 Understanding the Energy Landscape of Intrinsically Disordered Protein Ensembles

Viegas, R. G.; Martins, I. B. S.; LEITE, V. B. P.

10.1101/2024.01.04.574178 — biophysics — Posted on 2024-01-05

4023 An AI Agent for Fully Automated Multi-omic Analyses

Zhou, J.; Zhang, B.; Chen, X.; Li, H.; Xu, X.; Chen, S.; He, W.; Xu, C.; Gao, X.

10.1101/2023.09.08.556814 — bioinformatics — Posted on 2024-01-05

4024 State-of-the-RNArt: benchmarking current methods for RNA 3D structure prediction

Bernard, C.; Postic, G.; Ghannay, S.; Tahi, F.

10.1101/2023.12.22.573067 — bioinformatics — Posted on 2024-01-05

4025 Pairing interacting protein sequences using masked language modeling

Lupo, U.; Sgarbossa, D.; Bitbol, A.-F.

10.1101/2023.08.14.553209 — bioinformatics — Posted on 2024-01-05

4026 SUMO's intrinsically disordered N-terminus is an intramolecular inhibitor of SUMO - SIM interactions

Richter, S. M.; Jin, F.; Ritterhoff, T.; Fergin, A.; Maurer, E.; Frank, A.; Hajnal, A.; Klevit, R. E.; Gräter, F.; Flotho, A.; Melchior, F.

10.1101/2024.01.04.574143 — biochemistry — Posted on 2024-01-05

4027 Behavioural Investigations of Psilocybin in Animals 1962-2021: A Scoping Review

Shore, R. J.; Dobson, K.; Thomson, N.; Barnim, N.; Bergman, H.; Rideout, K.; Mckeown, S.; Olmstead, M.; Goldie, C.; Dumont, E.

10.1101/2024.01.04.574146 — animal behavior and cognition — Posted on 2024-01-05

4028 Single-cell transcriptional dynamics in a living vertebrate

Eck, E.; Moretti, B.; Schlomann, B. H.; Bragantini, J.; Lange, M.; Zhao, X.; VijayKumar, S.; Valentin, G.; Loureiro, C.; Soroldoni, D.; Royer, L. A.; Oates, A. C.; Garcia, H. H.

10.1101/2024.01.03.574108 — developmental biology — Posted on 2024-01-05

4029 Chemical imaging unveils mitochondria as the major site of medicinal biguanide accumulation within cells

Wang, L.; Zeng, X.; Li, Y.; Hao, W.; Yu, Z.; Yao, L.; Zhang, Y.; Wang, Z.; Wu, L.

10.1101/2024.01.02.573981 — molecular biology — Posted on 2024-01-05

4030 Rhizospheric bacteria from the Atacama Desert hyper-arid core: cultured community dynamics and plant growth promotion

Castro-Severyn, J.; Fortt, J.; Sierralta, M.; Alegria, P.; Donoso, G.; Choque, A.; Avellaneda, A. M.; Pardo-Este, C.; Saavedra, C. P.; Stoll, A.; Remonsellez, F.

10.1101/2024.01.04.574204 — microbiology — Posted on 2024-01-05

4031 Insights into Human Epileptogenesis with Proteomic Profiling

Zhou, N.; Zhang, H.; Li, W.; Du, X.; Di, Y.; Zhang, D.; Gang, W.; Yuan, Y.; Zhang, A.; Dai, J.; Zhang, H.

10.1101/2024.01.01.573812 — neuroscience — Posted on 2024-01-05

4032 Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy

10.1101/2024.01.04.574177 — neuroscience — Posted on 2024-01-05

4033 Shaping the physical world to our ends: The left PF technical-cognition area

Osiurak, F.; Federico, G.; Fournel, A.; Gaujoux, V.; Lamberton, F.; Ibarrola, D.; Rossetti, Y.; Lesourd, M.

10.1101/2024.01.02.573935 — neuroscience — Posted on 2024-01-05

4034 Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure

Walle, R.; Petitbon, A.; Fois, G. R.; Varin, C.; Montalban, E.; Hardt, L.; Contini, A.; Angelo, M. F.; Potier, M.; Ortole, R.; Oummadi, A.; Desmedt-Peyrusse, V.; adan, r.; GIROS, B.; Chaouloff, F.; Ferreira, G.; de Kerchove d'Exaerde, A.; Ducrocq, F.; Georges, F.; Trifilieff, P.

10.1101/2022.05.05.490599 — neuroscience — Posted on 2024-01-05

4035 Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis

Horn, P.; Norlin, J.; Almholt, K.; Viuff, B. M.; Galsgaard, E. D.; Hald, A.; Zosel, F.; Demuth, H.; Poulsen, S.; Norby, P. L.; Rasch, M. G.; Vyberg, M.; Rink, M. R.; Shepherd, E.; Northall, E.; Lalor, P. F.; Weston, C. J.; Fog-Tonnesen, M.; Newsome, P.

10.1101/2024.01.03.574043 — pathology — Posted on 2024-01-05

4036 IDSL.GOA: Gene Ontology Analysis for Interpreting Metabolomic datasets

Mahajan, P.; Fiehn, O.; Barupal, D. K.

10.1101/2023.03.25.534225 — bioinformatics — Posted on 2024-01-05

4037 Evolution and diversity of biomineralized columnar architecture in early Cambrian phosphatic-shelled brachiopods

Zhang, Z.; Zhang, Z.; Holmer, L. E.; Topper, T. P.; Pan, B.; Li, G.

10.1101/2023.06.01.543202 — evolutionary biology — Posted on 2024-01-05

4038 Distinct human stem cell subpopulations drive adipogenesis and fibrosis in musculoskeletal injury

Garcia, S. M.; Lau, J.; Diaz, A.; Chi, H. M.; Lizarraga, M.; Lizarraga, M.; Wague, A.; Montenegro, C.; Davies, M. R.; Liu, X.; Feeley, B. T.

10.1101/2023.07.28.551038 — cell biology — Posted on 2024-01-05

4039 Microbial Interactions from a New Perspective: Reinforcement Learning Reveals New Insights into Microbiome Evolution

Ghadermazi, P.; Chan, S. H. J.

10.1101/2023.05.07.539711 — systems biology — Posted on 2024-01-05

4040 Scientific civility and academic performance

Camacho, E.; Dragotakes, Q.; Hartshorn, I.; Casadevall, A.; Buccino, D. L.

10.1101/2023.01.26.525747 — scientific communication and education — Posted on 2024-01-05

4041 TEMINET: A Co-Informative and Trustworthy Multi-Omics Integration Network for Diagnostic Prediction

Luo, H.; Liang, H.; Liu, H.; Fan, Z.; Wei, Y.; Yao, X.; Cong, S.

10.1101/2024.01.03.574118 — bioinformatics — Posted on 2024-01-05

4042 Theory on the rate equations of Michaelis-Menten type enzyme kinetics with competitive inhibition

Murugan, R.

10.1101/2022.11.28.518182 — biochemistry — Posted on 2024-01-05

4043 A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors

Menon, I.; Sych, T.; Son, Y.; Morizumi, T.; Lee, J.; Ernst, O. P.; Khelashvili, G.; Sezgin, E.; Levitz, J.; Menon, A. K.

10.1101/2023.11.24.568580 — biochemistry — Posted on 2024-01-05

4044 A comprehensive landscape of the zinc-regulated human proteome

Burger, N.; Mittenbuhler, M.; Xiao, H.; Shin, S.; Bozi, L.; Wei, S.; Sprenger, H.-G.; Sun, Y.; Zhu, Y.; Darabedian, N.; Petrocelli, J.; Latorre Muro, P.; Che, J.; Chouchani, E. T.

10.1101/2024.01.04.574225 — cell biology — Posted on 2024-01-05

4045 GMT systems define a new class of mobile elements rich in bacterial defensive and offensive tools

Mahata, T.; Kanarek, K.; Goren, M. G.; Ragavan, R. M.; Bosis, E.; Qimron, U.; Salomon, D.

10.1101/2023.03.28.534373 — microbiology — Posted on 2024-01-05

4046 Revisit the Inhibitory Effects of Glucocorticoids on Immunocytes

Wu, S.; Zhao, S.; Zhong, Y.; Wang, B.

10.1101/2023.01.28.525640 — immunology — Posted on 2024-01-05

4047 Metabolic and behavioral alterations associated with viral vector-mediated toxicity in the paraventricular hypothalamic nucleus

Savani, R.; Park, E.; Busannagari, N.; Lu, Y.; Kwon, H.; Wang, L.; Pang, Z. P.

10.1101/2023.10.26.564009 — neuroscience — Posted on 2024-01-05

4048 Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation'

Taniguchi, J.; Melani, R.; Chantranupong, L.; Wen, M. J.; Mohebi, A.; Berke, J. D.; Sabatini, B. L.; Tritsch, N. X.

10.1101/2023.12.27.573485 — neuroscience — Posted on 2024-01-05

4049 Saturated fatty acid-Coenzyme A supplementation restores neuronal energy levels, synaptic function, and protein homeostasis in hereditary spastic paraplegia

Saber, S. H.; Yak, N.; Yong, X. L. H.; Lu, S.; Binder, T.; Purushothaman, R.; Gaudin, A.; Harmer, J.; Talbo, G. H.; van Waardenberg, A. J.; Anggono, V.; Balistreri, G.; Joensuu, M.

10.1101/2023.12.31.573799 — neuroscience — Posted on 2024-01-05

4050 Photobody formation spatially segregates two opposing phytochrome B signaling actions to titrate plant environmental responses

Kim, R. J. A.; Fan, D.; He, J.; Kim, K.; Du, J.; Chen, M.

10.1101/2023.11.12.566724 — plant biology — Posted on 2024-01-05

4051 Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation

Thim, E. A.; Petricca, L. E.; Mathew, A. S.; Rivera-Escalera, F.; Elliott, M. R.; Bullock, T. N.; Price, R. J.

10.1101/2023.09.02.552844 — bioengineering — Posted on 2024-01-05

4052 Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection

Kerr, C. M.; Pfannenstiel, J. J.; Alhammad, Y. M.; Roy, A.; O'Connor, J. J.; Ghimire, R.; Khattabi, R.; Shrestha, R.; McDonald, P. R.; Gao, P.; Johnson, D. K.; More, S.; Channappanavar, R.; Fehr, A. R.

10.1101/2024.01.03.574082 — microbiology — Posted on 2024-01-04

4053 Predicting RNA Sequence-Structure Likelihood via Structure-Aware Deep Learning

Zhou, Y.; Pedrielli, G.; Zhang, F.; Wu, T.

10.1101/2024.01.04.574208 — bioinformatics — Posted on 2024-01-04

4054 Antiviral action of different molecules obtained from invertebrates against coronavirus

Mendonca, R. Z.; Nascimento, R. M.; Fernandes, A. C. O.; de Almeida, M. I. P.; Junior, P. I. S.

10.1101/2024.01.04.574161 — microbiology — Posted on 2024-01-04

4055 Personalized Clostridioides difficile engraftment risk prediction and probiotic therapy assessment in the human gut.

Carr, A.; Baliga, N. S.; Diener, C.; Gibbons, S. M.

10.1101/2023.04.28.538771 — systems biology — Posted on 2024-01-04

4056 Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing

Lee, J.-H.; LeCher, J. C.; Parigoris, E.; Shinagawa, N.; Sentosa, J.; Manfredi, C.; Goh, S. L.; De, R.; Tao, S.; Zandi, K.; Amblard, F.; Sorscher, E. J.; Spence, J. R.; Tirouvanziam, R.; Schinazi, R. F.; Takayama, S.

10.1101/2024.01.02.573939 — bioengineering — Posted on 2024-01-04

4057 FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells

Cong, K.; MacGilvary, N.; Lee, S.; MacLeod, S.; Calvo, J.; Peng, M.; Nedergaard Kousholt, A.; Day, T.; Cantor, S.

10.1101/2024.01.04.574095 — molecular biology — Posted on 2024-01-04

4058 Laboratory evolution of E. coli with a natural vitamin B12 analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth

Mok, K. C.; Hallberg, Z.; Procknow, R. R.; Taga, M. E.

10.1101/2024.01.04.574217 — microbiology — Posted on 2024-01-04

4059 Species-associated bacterial diversity increases along a gradient of habitat degradation

Hanhimaki, E.; Linna, S.; Beraldo, C.; Englund, M.; Rezola, U.; Cardoso, P.; Thorogood, R.; Saastamoinen, M.; Duplouy, A.

10.1101/2024.01.04.574207 — microbiology — Posted on 2024-01-04

4060 Genomic and transcriptomic characteristics of type VI secretion system in Klebsiella pneumoniae

Zhang, J.; Li, W.; Huang, X.; Li, D.; Liu, X.; Jiang, X.; Bian, X.; Li, X.

10.1101/2024.01.04.574191 — microbiology — Posted on 2024-01-04

4061 Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2-related Pangolin Coronavirus GX_P2V(short_3UTR)

Wei, L.; Liu, S.; Lu, S.; Luo, S.; An, X.; Fan, H.; Chen, W.; Li, E.; Tong, Y.; Song, L.

10.1101/2024.01.03.574008 — microbiology — Posted on 2024-01-04

4062 A Murine Model of Post-acute Neurological Sequelae Following SARS-CoV-2 Variant Infection

Singh, A.; Adam, A.; Aditi, A.; Peng, B.-H.; Yu, X.; Zou, J.; Kulkarni, V. V.; Kan, P.; Jiang, W.; Shi, P.-Y.; Samir, P.; Cisneros, I.; Wang, T.

10.1101/2024.01.03.574064 — microbiology — Posted on 2024-01-04

4063 Air pollution drives macrophage senescence through a phagolysosome-15-lipoxygenase pathway

Thomas, S. A.; Yong, H. M.; Rule, A. M.; Gour, N.; Lajoie, S.

10.1101/2024.01.04.574228 — immunology — Posted on 2024-01-04

4064 Prototype mRNA vaccines imprint broadly neutralizing human serum antibodies after Omicron variant-matched boosting

Liang, C.-Y.; Raju, S.; Liu, Z.; Li, Y.; Arunkumar, G. A.; Case, J. B.; Zost, S. J.; Acreman, C. M.; Carvalho dos Anjos, D. C.; McLellan, J. S.; Crowe, J. E.; Whelan, S. P. J.; Elbashir, S. M.; Edwards, D. K.; Diamond, M. S.

10.1101/2024.01.03.574018 — immunology — Posted on 2024-01-04

4065 Compact RNA sensors for increasingly complex functions of multiple inputs

Choe, C. A.; Andreasson, J. O. L.; Melaine, F.; Kladwang, W.; Wu, M. J.; Portela, F.; Wellington-Oguri, R.; Nicol, J. J.; Wayment-Steele, H. K.; Gotrik, M.; Eterna Participants, ; Kahtri, P.; Greenleaf, W. J.; Das, R.

10.1101/2024.01.04.572289 — synthetic biology — Posted on 2024-01-04

4066 Dietary methionine/choline deficiency affects behavioural and molecular circadian rhythms

Saer, B.; Taylor, G.; Hayes, A.; Ananthasubramaniam, B.; Fustin, J.-M.

10.1101/2024.01.04.574014 — physiology — Posted on 2024-01-04

4067 Molecular mechanisms underlying single nucleotidepolymorphism-induced reactivity decrease in CYP2D6

Becker, D.; Bharatam, P. V.; Gohlke, H.

10.1101/2024.01.04.574226 — biochemistry — Posted on 2024-01-04

4068 The topography of DNA replication origins in Eukarya: GGN clusters, landmark nucleosomes, CDC6 and G4 structures

Bastolla, U.; Gomez-Pinto, I.; Vergara, Z.; Gomez, M.; Gonzalez, C.; Gutierrez, C.

10.1101/2024.01.04.574144 — genomics — Posted on 2024-01-04

4069 The majority of somatic mutations in fruit trees are layer-specific

Goel, M.; Campoy, J. A.; Krause, K.; Baus, L. C.; Sahu, A.; Sun, H.; Walkemeier, B.; Marek, M.; Beaudry, R.; Ruiz, D.; Huettel, B.; Schneeberger, K.

10.1101/2024.01.04.573414 — genomics — Posted on 2024-01-04

4070 Species Tree Topology Impacts the Inference of Ancient Whole-Genome Duplications Across the Angiosperm Phylogeny

McKibben, M. T. W.; Finch, G.; Barker, M. S.

10.1101/2024.01.04.574202 — evolutionary biology — Posted on 2024-01-04

4071 A speed limit on serial strain replacement from original antigenic sin

McGough, L.; Cobey, S.

10.1101/2024.01.04.574172 — evolutionary biology — Posted on 2024-01-04

4072 Constraint on boric acid resistance and tolerance evolvability in Candida albicans

Syvolos, Y.; Salama, O.; Gerstein, A.

10.1101/2024.01.04.574193 — evolutionary biology — Posted on 2024-01-04

4073 Emx2 is an essential regulator of ciliated cell development across embryonic tissues

Nguyen, T. K.; Rodriguez, J.-M.; Wesselman, H.; Wingert, R. A.

10.1101/2024.01.04.574218 — developmental biology — Posted on 2024-01-04

4074 An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal and neural cells

Moerkens, R.; Mooiweer, J.; Ramirez-Sanchez, A. D.; Oelen, R.; Franke, L.; Wijmenga, C.; Barrett, R. J.; Jonkers, I. H.; Withoff, S.

10.1101/2024.01.04.574203 — cell biology — Posted on 2024-01-04

4075 B-Cell Involvement in Immune Checkpoint Inhibitor-Induced Lichen Planus: A Comparative Analysis with Non-Drug-Related Lichen Planus.

Tison, A.; Legoupil, D.; Le Rochais, M.; Hemon, P.; Foulquier, N.; Hardy, Q.; Hillion, S.; Uguen, A.; Pers, J.-O.; Misery, L.; Cornec, D.; Garaud, S.

10.1101/2024.01.04.574049 — immunology — Posted on 2024-01-04

4076 Altered Socio-Affective Communication and Amygdala Development in mice with Protocadherin10-deficient Interneurons

Aerts, T.; Boonen, A.; Geenen, L.; Stulens, A.; Masin, L.; Pancho, A.; Francis, A.; Van Roy, F.; Wöhr, M.; Seuntjens, E.

10.1101/2024.01.04.574190 — neuroscience — Posted on 2024-01-04

4077 Genome binding properties of Zic transcription factors underlie their changing functions during neuronal maturation

Minto, M.; Sotelo-Fonseca, J. E.; Ramesh, V.; West, A. E.

10.1101/2024.01.04.574185 — neuroscience — Posted on 2024-01-04

4078 Diabetes alters neuroeconomically dissociable forms of mental accounting

Nwakama, C.; Durand-de Cuttoli, R.; Oketokoun, Z. M.; Brown, S. O.; Haller, J. E.; Mendez, A.; Farshbaf, M. J.; Cho, Y. Z.; Ahmed, S.; Leng, S.; Ables, J. L.; Sweis, B. M.

10.1101/2024.01.04.574210 — neuroscience — Posted on 2024-01-04

4079 Normal and Aberrant Cell Cycles Characterized by a Continuous-Time Stochastic Boolean Model of Cell Cycle Regulation in Budding Yeast

Taoma, K.; Tyson, J. J.; Laomettachit, T.; Kraikivski, P.

10.1101/2024.01.04.574212 — systems biology — Posted on 2024-01-04

4080 Unveiling the Impact of Vernalization on Seed Oil Content and Fatty Acid Composition in Rapeseed Through Simulated Shorter Winters

Cagli, I.; Kivrak, B. E.; Altunbas, O.; Sonmez, C.

10.1101/2024.01.04.574184 — plant biology — Posted on 2024-01-04

4081 KATANIN-mediated microtubule severing is required for MTOC formation and function in Marchantia polymorpha

Attrill, S. T.; Dolan, L.

10.1101/2024.01.04.574198 — plant biology — Posted on 2024-01-04

4082 How Older Adults Maintain Lateral Balance While Walking on Narrowing Paths

Kazanski, M. E.; Cusumano, J. P.; Dingwell, J. B.

10.1101/2024.01.04.574192 — bioengineering — Posted on 2024-01-04

4083 Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes

Nemkov, T.; Stephenson, D.; Earley, E. J.; Keele, G. R.; Hay, A.; Key, A. M.; Haiman, Z.; Erickson, C.; Dzieciatkowska, M.; Churchill, G. A.; Moore, A.; Stone, M.; Deng, X.; Kleinman, S.; Spitalnik, S. L.; Hod, E. A.; Hudson, K. E.; Hansen, K. C.; Palsson, B. O.; Roubinian, N.; Norris, P. J.; Busch, M. P.; Zimring, J. C.; Page, G. P.; D'Alessandro, A.; Reisz, J. A.

10.1101/2023.09.11.557250 — biochemistry — Posted on 2024-01-04

4084 Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling

Shim, A.; Luan, X.; Zhou, W.; Crow, Y.; Maciejowski, J.

10.1101/2024.01.04.574136 — genetics — Posted on 2024-01-04

4085 Obox4 promotes zygotic genome activation upon loss of Dux

Guo, Y.; Kitano, T.; Inoue, K.; Murano, K.; Hirose, M.; Li, T. D.; Sakashita, A.; Ishizu, H.; Ogonuki, N.; Matoba, S.; Sato, M.; Ogura, A.; Siomi, H.

10.1101/2022.07.04.498763 — developmental biology — Posted on 2024-01-04

4086 Endothelial cell flow-mediated quiescence is temporally regulated and utilizes the cell cycle inhibitor p27

Tanke, N.; Liu, Z.; Gore, M. T.; Bougaran, P.; Linares, M. B.; Marvin, A.; Sharma, A.; Oatley, M.; Yu, T.; Quigley, K.; Vest, S.; Cook, J. G.; Bautch, V. L.

10.1101/2023.06.09.544403 — cell biology — Posted on 2024-01-04

4087 Armed Macrophages as Hunters for Photodynamic Therapy of Systemic Bacterial Infections by Bathing in the Sunshine

Wang, Z.; Wang, L.; Zhou, L.; Zhang, X.; Xiao, Y.

10.1101/2024.01.04.574019 — microbiology — Posted on 2024-01-04

4088 Age differences in functional connectivity track dedifferentiation of category representations

Pauley, C.; Zeithamova, D.; Sander, M. C.

10.1101/2024.01.04.574135 — neuroscience — Posted on 2024-01-04

4089 Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons

Lepine, S.; Nauleau-Javaudin, A.; Deneault, E.; Chen, C. X.- Q.; Abdian, N.; Franco-Flores, A. K.; Haghi, G.; Castellanos-Montiel, M. J.; Maussion, G.; Chaineau, M.; Durcan, T. M.

10.1101/2023.03.22.533562 — neuroscience — Posted on 2024-01-04

4090 Chrysin directing an enhanced solubility through the formation of a supramolecular cyclodextrin-calixarene drug delivery system: a potential strategy in antifibrotic diabetes therapeutics

Hermenean, A.; Dossi, E.; Hamilton, A.; Trotta, M. C.; Russo, M.; Lepre, C. C.; Sajtos, C.; Rusznyak, A.; Varadi, J.; Bacskay, I.; Budai, I.; DAmico, M.; Fenyvesi, F.

10.1101/2023.10.03.560552 — pharmacology and toxicology — Posted on 2024-01-04

4091 Predicting the subcellular location of prokaryotic proteins with DeepLocPro

Moreno, J.; Nielsen, H.; Winther, O.; Teufel, F.

10.1101/2024.01.04.574157 — bioinformatics — Posted on 2024-01-04

4092 The Interpretable Multimodal Machine Learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy

Nguyen, P. B.; Garger, D.; Lu, D.; Maalmi, H.; Prokisch, H.; Thorand, B.; Adamski, J.; Kastenmueller, G.; Waldenberger, M.; Gieger, C.; Peters, A.; Suhre, K.; Boenhof, G. J.; Rathmann, W.; Roden, M.; Grallert, H.; Ziegler, D.; Herder, C.; Menden, M.

10.1101/2024.01.04.574164 — bioinformatics — Posted on 2024-01-04

4093 NeoCOMM: A Neocortical Neuroinspired Computational Model for the Reconstruction and Simulation of Epileptiform Events

Al Harrach, M.; Yochum, M.; Ruffini, G.; Bartolomei, F.; benquet, P.; Wendling, F.

10.1101/2024.01.04.574141 — bioengineering — Posted on 2024-01-04

4094 Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation

Trenker, R.; Diwanji, D.; Bingham, T.; Verba, K. A.; Jura, N.

10.1101/2023.10.06.561161 — biochemistry — Posted on 2024-01-04

4095 A split crRNA with CRISPR-Cas12a enables highly sensitive, selective, and multiplexed detection of RNA and DNA

Qiao, J.; Chen, Y.; Wang, X.; Yin, W.; He, B.; Liu, Y.

10.1101/2024.01.04.574169 — biochemistry — Posted on 2024-01-04

4096 Neurotrophic factor MANF regulates autophagy and lysosome function to promote proteostasis in C. elegans

Taylor, S. K. B.; Hartman, J. H.; Gupta, B. P.

10.1101/2023.07.31.551399 — genetics — Posted on 2024-01-04

4097 Integrator-mediated clustering of poised RNA polymerase II synchronizes histone transcription

Lu, F.; Park, B. J.; Fujiwara, R.; Wilusz, J. E.; Gilmour, D. S.; Lehmann, R.; Lionnet, T.

10.1101/2023.10.07.561364 — genetics — Posted on 2024-01-04

4098 ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

Menon, D. U.; Chakraborty, P.; Murcia, N.; Magnuson, T.

10.1101/2023.05.25.542290 — developmental biology — Posted on 2024-01-04

4099 Vascular damage and excessive proliferation compromise liver function after extended hepatectomy in mice

De Rudder, M.; Manco, R.; Coubeau, L.; Fontaine, A.; Bertrand, C.; Leclercq, I.; Dili, A.

10.1101/2024.01.04.573041 — cell biology — Posted on 2024-01-04

4100 Human cytomegalovirus deploys molecular mimicry to recruit VPS4A to sites of virus assembly

Butt, B. G.; Fischer, D.; Rep, A. R.; Schauflinger, M.; Read, C.; Bock, T.; Hirner, M.; Graham, S. C.; von Einem, J.

10.1101/2024.01.04.572781 — cell biology — Posted on 2024-01-04

4101 Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments

Begnis, M.; Duc, J.; Offner, S.; Grun, D.; Sheppard, S.; Rosspopoff, O.; Trono, D.

10.1101/2024.01.04.574183 — molecular biology — Posted on 2024-01-04

4102 Spatial propagation of temperate phages within and among biofilms

Winans, J.; Garcia, S.; Zeng, L.; Nadell, C.

10.1101/2023.12.20.571119 — microbiology — Posted on 2024-01-04

4103 Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors

Johnston, A. C.; Alicea, G. M.; Lee, C. C.; Patel, P. V.; Hanna, E. A.; Vaz, E.; Forjaz, A.; Wan, Z.; Nair, P. R.; Lim, Y.; Chen, T.; Du, W.; Kim, D.; Nichakawade, T. D.; Rebecca, V. W.; Bonifant, C. L.; Fan, R.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.

10.1101/2023.12.13.571595 — immunology — Posted on 2024-01-04

4104 Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

Stuchly, J.; Novak, D.; Brdickova, N.; Hadlova, P.; Iksi, A.; Kuzilkova, D.; Svaton, M.; Saad, G. A.; Engel, P.; Luche, H.; Sousa, A. E.; Almeida, A. R. M.; Kalina, T.

10.1101/2023.07.13.547329 — immunology — Posted on 2024-01-04

4105 The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study

Rier, L.; Rhodes, N.; Pakenham, D.; Boto, E.; Holmes, N.; Hill, R. M.; Reina Rivero, G.; Shah, V.; Doyle, C.; Osborne, J.; Bowtell, R. W.; Taylor, M.; Brookes, M. J.

10.1101/2024.01.04.573933 — neuroscience — Posted on 2024-01-04

4106 Impaired Visuospatial Working Memory but Preserved Attentional Control in Bipolar Disorder

Barnes-Scheufler, C. V.; Roesler, L.; Schiweck, C.; Peters, B.; Matura, S.; Mayer, J. S.; Kittel-Schneider, S.; Schaum, M.; Reif, A.; Wibral, M.; Bittner, R. A.

10.1101/2024.01.04.574011 — neuroscience — Posted on 2024-01-04

4107 Identifying the genetic and epigenetic basis for asymmetric bZIP expression in temperature-stressed bread wheat

Rishi, V.; Kaur, R.; Singh, D.; Singh, P. K.; Kaur, G.; Shah, K.; Pandey, H.; Devi, S. G.; Pandey, A. K.

10.1101/2024.01.04.574129 — plant biology — Posted on 2024-01-04

4108 Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis

Pham, C.; Komaki, Y.; Deas-Just, A.; Le Gac, B.; Mouffle, C.; Franco, C.; Vialou, V.; Tsurugizawa, T.; Cauli, B.; Li, D.

10.1101/2023.10.03.560471 — physiology — Posted on 2024-01-04

4109 3-epicaryoptin induces G2/M phase cell cycle arrest and apoptosis in human breast cancer cells by disrupting the microtubule network, an in vitro and in silico investigation

Barman, M.; Roy, S.; Singh, N.; Sarkar, D.; Barman, N.; Bhattacharyya, S.; Pal, A.; Ray, S.

10.1101/2024.01.04.574171 — cancer biology — Posted on 2024-01-04

4110 Identifying hierarchical cell states and gene signatures with deep exponential families for single-cell transcriptomics

Ferreira, P. F.; Kuipers, J.; Beerenwinkel, N.

10.1101/2022.10.15.512383 — bioinformatics — Posted on 2024-01-04

4111 DeepRod: A human-in-the-loop system for automatic rodent behavior analysis

Loy, A.; Garafolj, M.; Schauerte, H.; Behnke, H.; Charnier, C.; Schwarz, P.; Rast, G.; Wollmann, T.

10.1101/2024.01.04.572506 — animal behavior and cognition — Posted on 2024-01-04

4112 Insect hosts are nutritional landscapes navigated by fungal pathogens

De Fine Licht, H. H.; Csontos, Z.; Nielsen, P. J. D. N.; Langkilde, E. B.; Kjaergaard Hansen, A. K.; Shik, J. Z.

10.1101/2024.01.04.574030 — ecology — Posted on 2024-01-04

4113 Improving the application of Important Plant Areas to conserve threatened habitats: a case study of Uganda

Richards, S. L.; Kalema, J.; Ojelel, S.; Williams, J.; Darbyshire, I.

10.1101/2024.01.04.572590 — ecology — Posted on 2024-01-04

4114 Sorafenib induces muscle wasting by disrupting the activity of distinct chromatin regulators

Khan, B.; Lanzuolo, C.; Rosti, V.; Santarelli, P. A.; Pich, A.; Kraft, T.; Amrute-Nayak, M.; Nayak, A.

10.1101/2024.01.04.574149 — cell biology — Posted on 2024-01-04

4115 ROSALIND protects the mitochondrial translational machinery from oxidative damage

Katopodi, V.; Verheyden, Y.; Cinque, S.; Jimenez, E. L.; Demesmaeker, E.; Marino, A.; Derua, R.; Groaz, E.; Leucci, E.

10.1101/2024.01.04.574152 — molecular biology — Posted on 2024-01-04

4116 AMAPEC: accurate antimicrobial activity prediction for fungal effector proteins

Mesny, F.; Thomma, B. P.

10.1101/2024.01.04.574150 — microbiology — Posted on 2024-01-04

4117 Single-cell RNA sequencing of peripheral blood mononuclear cells reveals complex cellular signalling signatures of metformin treatment type 2 diabetes mellitus

zhao, j.; fang, z.

10.1101/2024.01.04.574155 — immunology — Posted on 2024-01-04

4118 Linking brain-heart interactions to emotional arousal in immersive virtual reality

Fourcade, A.; Klotzsche, F.; Hofmann, S. M.; Mariola, A.; Nikulin, V.; Villringer, A.; Gaebler, M.

10.1101/2024.01.04.574165 — neuroscience — Posted on 2024-01-04

4119 Selfish behavior requires top-down control of prosocial motivation

Numano, S.; Frith, C.; Haruno, M.

10.1101/2024.01.04.574159 — neuroscience — Posted on 2024-01-04

4120 A polytypic species revisited: Phylogenetic and morphological variation, taxonomic status, and geographical distribution of Trachops (Chiroptera: Phyllostomidae)

Camacho, M. A.; Menendez-Guerrero, P. A.; Horvath, B.; Cadar, D.; Murienne, J.

10.1101/2024.01.04.574068 — zoology — Posted on 2024-01-04

4121 Revisiting soil fungal biomarkers and conversion factors: Interspecific variability in phospholipid fatty acids, ergosterol and rDNA copy numbers

Camenzind, T.; Haslwimmer, H.; Rillig, M. C.; Ruess, L.; Finn, D. R.; Tebbe, C. C.; Hempel, S.; Marhan, S.

10.1101/2024.01.04.574151 — ecology — Posted on 2024-01-04

4122 CDC5L surveils cellular stress responses and stress granule formation through transcriptional repression

Qian, B.; Li, S.; Duan, Y.; Qiu, F.; Hu, R.; Yue, W.; Cui, J.; Wang, Q.; Li, W.; Fang, Y.

10.1101/2024.01.04.574133 — cell biology — Posted on 2024-01-04

4123 Checkpoint-independent association of Mad3BUBR1 with Stu1CLASP directs homolog alignment in meiosis I

Mukherjee, A.; Spanos, C.; Marston, A. L.

10.1101/2024.01.04.574163 — cell biology — Posted on 2024-01-04

4124 Molecular detection using hybridization capture and next-generation sequencing reveals cross-species transmission of feline coronavirus type-1 between a domestic cat and a captive wild felid

Olarte-Castillo, X. A.; Goodman, L. B.; Whittaker, G. R.

10.1101/2024.01.02.573944 — microbiology — Posted on 2024-01-04

4125 ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation

Fiskum, V.; Winter-Hjelm, N.; Christiansen, N.; Sandvig, A.; Sandvig, I.

10.1101/2024.01.04.574167 — neuroscience — Posted on 2024-01-04

4126 Fluorescence lifetime imaging of sDarken as a tool for the evaluation of serotonin levels

Kubitschke, M.; Beck, V.; Masseck, O. A.

10.1101/2024.01.04.574197 — neuroscience — Posted on 2024-01-04

4127 Cell-cycle dependent DNA repair and replication unifies patterns of chromosome instability

Lu, B.; Winnall, S.; Cross, W.; Barnes, C. P.

10.1101/2024.01.03.574048 — genomics — Posted on 2024-01-04

4128 Complementation testing identifies causal genes at quantitative trait loci underlying fear related behavior

Chen, P. B.; Chen, R.; LaPierre, N. R. S.; Chen, Z.; Mefford, J.; Marcus, E.; Heffel, M.; Soto, D. C.; Ernst, J.; Luo, C.; Flint, J.

10.1101/2024.01.03.574060 — genetics — Posted on 2024-01-04

4129 Consistent accumulation of transposable elements in species of the Hawaiian Tetragnatha spiny-leg adaptive radiation across the archipelago chronosequence

Yang, H.; Goubert, C.; Cotoras, D.; Graham, N.; Cerca, J.; Gillespie, R. G.

10.1101/2024.01.03.574070 — evolutionary biology — Posted on 2024-01-04

4130 Loss of αBa-crystallin, but not αA-crystallin, increases age-related cataract in the zebrafish lens

Posner, M.; Garver, T.; Kaye, T.; Brdicka, S.; Suttle, M.; Patterson, B.; Farnsworth, D. R.

10.1101/2024.01.03.574085 — developmental biology — Posted on 2024-01-04

4131 Loss of Nkd1 is epistatic to loss of Axin2 in regulating Wnt signaling

Bell, I.; Khan, H.; Stutt, N.; Horn, M.; Hydzik, T.; Lum, W.; Rea, V.; Clapham, E.; Hoeg, L.; Van Raay, T. J.

10.1101/2023.10.30.563773 — developmental biology — Posted on 2024-01-04

4132 Un1Cas12f1 and Cas9 gene drive in HSV1: Viruses that 'infect' viruses

Yao, Q.; Lin, Z.; Lai, K.; Zeng, X.; Lei, G.; Zhang, T.; Dai, H.

10.1101/2023.12.04.569968 — microbiology — Posted on 2024-01-04

4133 Tractography-based automated identification of the retinogeniculate visual pathway with novel microstructure-informed supervised contrastive learning

Li, S.; Zhang, W.; Yao, S.; He, J.; Zhu, C.; Gao, J.; Xue, T.; Xie, G.; Chen, Y.; Torio, E. F.; Feng, Y.; CA Bastos, D.; Rathi, Y.; Makris, N.; Kikinis, R.; Bi, W. L.; Golby, A. J.; O'Donnell, L. J.; Zhang, F.

10.1101/2024.01.03.574115 — neuroscience — Posted on 2024-01-04

4134 Integrating Residual Networks and Symbolic Regression for Biological ODE System Modeling

Yi, Z.

10.1101/2024.01.01.573840 — systems biology — Posted on 2024-01-04

4135 Reconstructing cell histories in space with image-readable base editor recording

Chadly, D. M.; Frieda, K. L.; Gui, C.; Klock, L.; Tran, M.; Sui, M. Y.; Takei, Y.; Bouckaert, R.; Lois, C.; Cai, L.; Elowitz, M. B.

10.1101/2024.01.03.573434 — synthetic biology — Posted on 2024-01-04

4136 Light and temperature-dependent developmental role of Auxin Binding Protein 1 (ABP1) in Arabidopsis thaliana

Patnaik, A.; Behera, A.; Kumar, A.; Dalai, A.; Mukundan, S.; Priyadarshini, N.; PANIGRAHY, M.; Panigrahi, K. C.

10.1101/2024.01.03.574050 — plant biology — Posted on 2024-01-04

4137 Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade

Powers, J.; Zhang, X.; Reyes, A. V.; Zavaliev, R.; Xu, S.-L.; Dong, X.

10.1101/2024.01.03.574047 — plant biology — Posted on 2024-01-04

4138 Leveraging Soil Mapping and Machine Learning to Improve Spatial Adjustments in Plant Breeding Trials

Carroll, M. E.; Riera, L. G.; Miller, B. A.; Dixon, P. M.; Ganapathysubramanian, B.; Sarkar, S.; Singh, A. K.

10.1101/2024.01.03.574114 — plant biology — Posted on 2024-01-04

4139 Fascin structural plasticity mediates flexible actin bundle construction

Gong, R.; Reynolds, M. J.; Hamilton, K.; Alushin, G. M.

10.1101/2024.01.03.574123 — biophysics — Posted on 2024-01-04

4140 Protein language model powers accurate and fast sequence search for remote homology

Liu, W.; Wang, Z.; You, R.; Xie, C.; Wei, H.; Xiong, Y.; Yang, J.; Zhu, S.

10.1101/2023.04.03.535375 — bioinformatics — Posted on 2024-01-04

4141 Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants

McDonald, E. F.; Oliver, K. E.; Schlebach, J. P.; Meiler, J.; Plate, L.

10.1101/2023.10.05.561147 — bioinformatics — Posted on 2024-01-04

4142 Hidden route of protein damage through confined oxygen gas

Kim, S.; Kim, E.; Park, M.; Kim, S. H.; Kim, B.-G.; Sadongo, V. W.; Wijesinghe, W. C. B.; Eom, Y.-G.; Yoon, G.; Lee, C.; Jeong, H.; Kim, C. U.; Myung, K.; Choi, J.-M.; Min, S. K.; Kwon, T.-H.; Min, D.

10.1101/2024.01.03.574110 — biochemistry — Posted on 2024-01-04

4143 Soil respiration is correlated with rainfall and soil moisture at multiple temporal scales in a seasonal wet tropical forest.

Chakravarthy, D.; Raghavendra, H. V.; Ratnam, J.; Sankaran, M.

10.1101/2024.01.03.574121 — ecology — Posted on 2024-01-04

4144 Climate variables and urbanization drive changes in the distribution of S. mansoni competent snails in Brazil: novel results from a counterfactual analysis

Glidden, C. K.; Singleton, A. L.; Chamberlin, A.; Tuan, R.; Palasio, R. G. S.; Calderia, R.; Monteiro, A. M. V.; Lwiza, K. M.; Liu, P.; Silva, V.; Athni, T. S.; Sokolow, S. H.; De Leo, G. A.

10.1101/2024.01.03.574120 — ecology — Posted on 2024-01-04

4145 Between a Warm Winter and a Cold Spell: Physiological Responses to Changing Winter Climate in Amphibians

Schmidt, R.; Zummach, C.; Sinai, N.; Sabino-Pinto, J.; Kuenzel, S.; Dausmann, K. H.; Ruthsatz, K.

10.1101/2024.01.03.574103 — ecology — Posted on 2024-01-04

4146 Cell envelope structural and functional contributions to antibiotic resistance in Burkholderia cenocepacia

Hogan, A. M.; Motnenko, A.; Rahman, A. S. M. Z.; Cardona, S. T.

10.1101/2024.01.03.574096 — microbiology — Posted on 2024-01-04

4147 GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus

Mills, K. A. M.; Westermann, F.; Espinosa, V.; Rosiek, E.; Desai, J. V.; Aufiero, M. A.; Guo, Y.; Mitchell, K. A.; Tuzlak, S.; De Feo, D.; Lionakis, M. S.; Rivera, A.; Becher, B.; Hohl, T. M.

10.1101/2024.01.03.574062 — immunology — Posted on 2024-01-04

4148 Hippocampus oxytocin signaling promotes prosocial eating in rats

Rea, J. J.; Liu, C. M.; Hayes, A. M. R.; Bashaw, A. G.; Schwartz, G.; Ohan, R.; Decarie-Spain, L.; Kao, A. E.; Klug, M. E.; Phung, K. J.; Waldow, A. I.; Wood, R. I.; Kanoski, S. E.

10.1101/2024.01.03.574101 — neuroscience — Posted on 2024-01-04

4149 Spatiotemporal Mapping and Molecular Basis of Whole-brain Circuit Maturation

Xue, J.; Brawner, A. T.; Thompson, J. R.; Yelhekar, T. D.; Newmaster, K. T.; Qiu, Q.; Cooper, Y. A.; Yu, C. R.; Ahmed-Braima, Y. H.; Kim, Y.; Lin, Y.

10.1101/2024.01.03.572456 — neuroscience — Posted on 2024-01-04

4150 Strategic stabilization of arousal boosts sustained attention

de Gee, J. W.; Mridha, Z.; Hudson, M.; Shi, Y.; Ramsaywak, H.; Smith, S.; Karediya, N.; Thompson, M.; Jaspe, K.; Zhang, W.; McGinley, M. J.

10.1101/2022.03.04.482962 — neuroscience — Posted on 2024-01-04

4151 The Regulatory-Associated Protein of the Target of Rapamycin Complex, RAPTOR1B, interconnects with the photoperiod pathway to promote flowering in Arabidopsis

Urrea-Castellanos, R.; Calderan-Rodrigues, M. J.; Musialak-Lange, M.; Macharanda-Ganesh, A.; Wahl, V.; Caldana, C.

10.1101/2024.01.03.574092 — plant biology — Posted on 2024-01-04

4152 Enhancing radiotherapy response via intratumoral injection of the TLR9 agonist CpG to stimulate CD8 T cells in an autochthonous mouse model of sarcoma

Su, C.; Kent, C. L.; Pierpoint, M.; Floyd, W.; Luo, L.; Williams, N. T.; Ma, Y.; Peng, B.; Lazarides, A. L.; Subramanian, A.; Himes, J. E.; Perez, V. M.; Hernansaiz-Ballesteros, R. D.; Roche, K. E.; Modliszewski, J. L.; Selitsky, S. R.; Shinohara, M.; Wisdom, A. J.; Moding, E. J.; Mowery, Y. M.; Kirsch, D. G.

10.1101/2024.01.03.573968 — cancer biology — Posted on 2024-01-04

4153 Characterization of DSPE-mPEG raw materials from different vendors reveals differences in impurity profiles and polymer chain length polydispersity

Hackbusch, S.; White, S.; Du, M.

10.1101/2024.01.03.574088 — pharmacology and toxicology — Posted on 2024-01-04

4154 Mechanically stimulated osteocytes maintain tumor dormancy in bone metastasis of non-small cell lung cancer by releasing small extracellular vesicles

Xie, J.; Xu, Y.; Liu, X.; Long, L.; Chen, J.; Huang, C.; Shao, Y.; Cai, Z.; Zhang, Z.; Zhou, R.; Leng, J.; Bai, X.; Song, Q.

10.1101/2023.06.14.544869 — cancer biology — Posted on 2024-01-04

4155 Synergistic Modulation of Macrophages by Methotrexate and RELA siRNA Folate-Liposome: A Precision Therapy to Prevent Joint Degradation in Collagen-Induced Arthritic Rats

Nasra, S.; Bhatia, D.; Kumar, A.

10.1101/2024.01.03.574006 — pharmacology and toxicology — Posted on 2024-01-04

4156 Ileal mucus viscoelastic properties differ in Crohns disease

Kramer, C.; Rulff, H.; Ziegler, J. F.; Alzain, N.; Addante, A.; Kuppe, A.; Timm, S.; Schrade, P.; Bischoff, P.; Glauben, R.; Duerr, J.; Ochs, M.; Mall, M. A.; Gradzielski, M.; Siegmund, B.

10.1101/2024.01.03.574052 — biophysics — Posted on 2024-01-04

4157 Live-cell imaging under centrifugation characterized the cellular force for nuclear centration in the Caenorhabditis elegans embryo

Goda, M.; Shribak, M.; Ikeda, Z.; Okada, N.; Tani, T.; Goshima, G.; Oldenbourg, R.; Kimura, A.

10.1101/2024.01.03.574024 — biophysics — Posted on 2024-01-04

4158 Streamlining the alignment of UAV and ULS forest point clouds: an approach based on ground and tree stems

Puletti, N.; Innocenti, S.; Guasti, M.

10.1101/2024.01.03.574086 — bioinformatics — Posted on 2024-01-04

4159 Enhancing Antibody Language Models with Structural Information

Barton, J.; Galson, J. D.; Leem, J.

10.1101/2023.12.12.569610 — bioinformatics — Posted on 2024-01-04

4160 Predicting Alu exonization in the human genome with a deep learning model

He, Z.; Chen, O.; Phillips, N.; Pasquesi, G. I. M.; Sabunciyan, S.; Florea, L. D.

10.1101/2024.01.03.574099 — bioinformatics — Posted on 2024-01-04

4161 TEMINET: A Co-Informative and Trustworthy Multi-Omics Integration Network for Diagnostic Prediction

Luo, H.; Liang, H.; Liu, H.; Fan, Z.; Wei, Y.; Yao, X.; Cong, S.

10.1101/2024.01.03.574118 — bioinformatics — Posted on 2024-01-04

4162 Microbiome-induced Increases and Decreases in Bone Tissue Strength can be Initiated After Skeletal Maturity

Liu, C.; Cyphert, E. L.; Stephen, S. J.; Wang, B.; Morales, A.; Nixon, J.; Natsoulas, N.; Garcia, M.; Blazquez Carmona, P.; Vill, A.; Donnelly, E.; Brito, I. L.; Vashishth, D.; Hernandez, C. J.

10.1101/2024.01.03.574074 — bioengineering — Posted on 2024-01-04

4163 EPISOMAL VECTORS FOR STABLE PRODUCTION OF RECOMBINANT PROTEINS AND ENGINEERED ANTIBODIES

Fallahee, I.; Hawiger, D.

10.1101/2024.01.03.574076 — bioengineering — Posted on 2024-01-04

4164 Contrast-enhanced photon-counting micro-CT of tumor xenograft models

Li, M.; Guo, X.; Verma, A.; Rudkouskaya, A.; McKenna, A.; Intes, X. R. M.; Wang, G.; Barroso, M.

10.1101/2024.01.03.574097 — bioengineering — Posted on 2024-01-04

4165 Posttranscriptional tuning of gene expression over a large dynamic range in synthetic tobacco chloroplast operons

Yu, Q.; Tungsuchat-Huang, T.; Ioannou, A.; Barkan, A.; Maliga, P.

10.1101/2024.01.03.574089 — bioengineering — Posted on 2024-01-04

4166 Macromolecular crowding by hyaluronan: implications for binding reactions in the pericellular matrix and at the cell surface

Fernig, D. G.

10.1101/2024.01.03.573870 — biochemistry — Posted on 2024-01-04

4167 Unique and Common Agonists Activate the Insect Juvenile Hormone Receptor and the Human AHR

Sedlak, D.; Tuma, R.; Kolla, J. N.; Mokhamatam, R. B.; Bahrova, L.; Lisova, M.; Bittova, L.; Jindra, M.

10.1101/2024.01.03.574093 — biochemistry — Posted on 2024-01-04

4168 The clade-specific target recognition mechanisms of plant RISCs

Iwakawa, H.-o.

10.1101/2024.01.03.574122 — biochemistry — Posted on 2024-01-04

4169 Curcumin Inhibits Zika Virus NS3 Helicase Activity

Kumar, A.; Bhardwaj, A.; Joshi, R.; Bhardwaj, T.; Giri, R.

10.1101/2024.01.03.573903 — biochemistry — Posted on 2024-01-04

4170 Spatially resolved quantification of oxygen consumption rate in ex vivo lymph node slices

Anbaei, P.; Stevens, M. G.; Ball, A. G.; Bullock, T. N. J.; Pompano, R. R.

10.1101/2024.01.03.573955 — biochemistry — Posted on 2024-01-04

4171 SEX-SPECIFIC IMPACTS OF EARLY LIFE SLEEP DISRUPTION: ETHANOL SEEKING, SOCIAL INTERACTION, AND ANXIETY ARE DIFFERENTIALLY ALTERED IN ADOLESCENT PRAIRIE VOLES

Ginder, D. E.; Tinsley, C. E.; Kaiser, M. E.; Lim, M.

10.1101/2024.01.03.574112 — animal behavior and cognition — Posted on 2024-01-04

4172 Genomic dissection and mutation-specific target discovery for breast cancer PIK3CA hotspot mutations

Miranda, A. X.; Kemp, J.; Davidson, B. A.; Bellomo, S. E.; Agan, V. E.; Manoni, A. A.; Marchio, C.; Croessmann, S.; Park, B. H.; Hodges, E.

10.1101/2024.01.03.574067 — genomics — Posted on 2024-01-04

4173 Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer's disease microglia

Huang, A. Y.; Zhou, Z.; Talukdar, M.; Miller, M. B.; Chhouk, B.; Enyenihi, L.; Rosen, I.; Stronge, E.; Zhao, B.; Kim, D.; Choi, J.; Khoshkhoo, S.; Kim, J.; Ganz, J.; Travaglini, K. J.; Gabitto, M.; Hodge, R. D.; Kaplan, E.; Lein, E.; De Jager, P.; Bennett, D. A.; Lee, E. A.; Walsh, C. A.

10.1101/2024.01.03.574078 — genomics — Posted on 2024-01-04

4174 Fas2: A Tale of Two Chromosomes

Finegan, T. M.; Cammarota, C.; Mendoza Andrade, O.; Garoutte, A. M.; Bergstralh, D. T.

10.1101/2024.01.03.574100 — genetics — Posted on 2024-01-04

4175 Differences in selective profiles among single or double stranded DNA or RNA viruses. Statistical detection of its double or single stranded condition.

Valenzuela, C. Y.

10.1101/2024.01.03.574038 — evolutionary biology — Posted on 2024-01-04

4176 Optimal trade-off between boosted tolerance and growth fitness during adaptive evolution of yeast to ethanol shocks

Jacobus, A. P.; Cavassana, S. D.; Oliveira, I. I.; Barreto, J. A.; Rohwedder, E.; Frazzon, J.; Basso, T. P.; Basso, L. C.; Gross, J.

10.1101/2024.01.03.574056 — evolutionary biology — Posted on 2024-01-04

4177 Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease

Chen, Y.-C.; Maupas, A.; Nowick, K.

10.1101/2023.12.18.569574 — evolutionary biology — Posted on 2024-01-04

4178 Accuracy of phylogenetic reconstructions from continuous characters analyzed under parsimony and its parametric correlates

Tagliacollo, V.; de Pinna, M.; Chuctaya, J.; Datovo, A.

10.1101/2024.01.03.574081 — evolutionary biology — Posted on 2024-01-04

4179 Environmental biofilms versus POCIS: efficiency to highlight environmental presence of pharmaceuticals and their effect on biofilm microbiome

Chonova, T.; Bouchez, A.; Mondamert, L.; Aubertheau, E.; Labanowski, J.

10.1101/2024.01.03.573948 — ecology — Posted on 2024-01-04

4180 How much warming can mosquito vectors tolerate?

Couper, L.; Desire Uwera Nalukwago, D.; Lyberger, K.; Farner, J.; Mordecai, E. A.

10.1101/2024.01.03.574109 — ecology — Posted on 2024-01-04

4181 Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

Quan, J.; Yang, M.; Wang, X.; Cai, G.; Ding, R.; Zhuang, Z.; Zhou, S.; Tan, S.; Ruan, D.; Wu, J.; Zheng, E.; Zhang, Z.; Liu, L.; Meng, F.; Wu, J.; Xu, C.; Qiu, Y.; Wang, S.; Lin, M.; Li, S.; Ye, Y.; Zhou, F.; Lin, D.; Li, X.; Deng, S.; Zhang, Y.; Yao, Z.; Gao, X.; Yang, Y.; Liu, Y.; Zhan, Y.; Liu, Z.; Zhang, J.; Ma, F.; Yang, J.; Chen, Q.; Yang, J.; Ye, J.; Dong, L.; Gu, T.; Huang, S.; Xu, Z.; Li, Z.; Yang, J.; Huang, W.; Wu, Z.

10.1101/2024.01.03.574116 — developmental biology — Posted on 2024-01-04

4182 Identification of the main barriers to Ku accumulation in chromatin

Bossaert, M.; Moreno, A.; Peixoto, A.; Pillaire, M.-J.; Chanut, P.; Frit, P.; Calsou, P.; Loparo, J. J.; Britton, S.

10.1101/2024.01.03.574002 — molecular biology — Posted on 2024-01-04

4183 YY1 is a transcriptional activator of mouse LINE-1 Tf subfamily

Saha, K.; Nielsen, G. I.; Nandani, R.; Kong, L.; Ye, P.; An, W.

10.1101/2024.01.03.573552 — molecular biology — Posted on 2024-01-04

4184 Enzymatic modulation of the pulmonary glycocalyx alters susceptibility to Streptococcus pneumoniae

Goekeri, C.; Linke, K. A. K.; Hoffmann, K.; Lopez-Rodriguez, E.; Gluhovic, V.; Voss, A.; Kunder, S.; Zappe, A.; Timm, S.; Nettesheim, A.; Schickinger, S. M. K.; Zobel, C. M.; Pagel, K.; Gruber, A. D.; Ochs, M.; Witzenrath, M.; Nouailles, G.

10.1101/2024.01.03.573996 — molecular biology — Posted on 2024-01-04

4185 Two Distinct Regulatory Systems Control Pulcherrimin Biosynthesis in Bacillus subtilis

Fernandez, N. L.; Simmons, L. A.

10.1101/2024.01.03.574033 — microbiology — Posted on 2024-01-04

4186 Interspecies secreted surfactants induce emergent motility in Pseudomonas aeruginosa

Warrell, D. L.; Zarrella, T. M.; Machalek, C.; Khare, A.

10.1101/2024.01.03.573969 — microbiology — Posted on 2024-01-04

4187 Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in P. falciparum persister blood stages after drug treatment

Micchelli, C.; Percopo, C.; Traver, M.; Brzostowski, J.; Amin, S. N.; Prigge, S. T.; Sa, J. M.; Wellems, T.

10.1101/2024.01.03.574077 — microbiology — Posted on 2024-01-04

4188 Synaptic Proteomes of Cortical Interneuron Classes Revealed by Antibody Directed Proximity Labeling.

Battison, A. S.; Liddle, J.; Sumsky, S.; O'Connell, C.; Balsbaugh, J.; LoTurco, J.

10.1101/2024.01.03.574066 — neuroscience — Posted on 2024-01-04

4189 NeuroMechanics: Electrophysiological and Computational Methods to Accurately Estimate the Neural Drive to Muscles in Humans In Vivo

Caillet, A. H.; Phillips, A. T.; Modenese, L.; Farina, D.

10.1101/2024.01.03.574073 — neuroscience — Posted on 2024-01-04

4190 Implicit adaptation is modulated by the relevance of feedback

Parvin, D. E.; Tsay, J.; Dang, K. V.; Stover, A. R.; Ivry, R. B.; Morehead, R.

10.1101/2022.01.19.476924 — neuroscience — Posted on 2024-01-04

4191 Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism

Kulich, I.; Schmid, J.; Teplova, A.; Qi, L.; Friml, J.

10.1101/2023.08.30.555533 — plant biology — Posted on 2024-01-04

4192 A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria

Faniyan, T. S.; Zhang, X.; Morgan, D. A.; Robles, J.; Bathina, S.; Perry, R. J.; Brookes, P. S.; Rahmouni, K.; Chhabra, K. H.

10.1101/2023.09.01.555894 — physiology — Posted on 2024-01-04

4193 PRMT5 orchestrates EGFR and AKT networks to activate NFκB and promote EMT

Huang, L.; Ravi, M.; Zhang, X.-O.; Verdejo-Torres, O.; Shendy, N. A. M.; Nezhady, M. A. M.; Gopalan, S.; Wang, G.; Durbin, A. D.; Fazzio, T. G.; Wu, J. Q.

10.1101/2024.01.03.574104 — cancer biology — Posted on 2024-01-04

4194 A realistic benchmark for the identification of differentially abundant taxa in (confounded) human microbiome studies

Wirbel, J.; Essex, M.; Forslund, S. K.; Zeller, G.

10.1101/2022.05.09.491139 — bioinformatics — Posted on 2024-01-04

4195 A Neural Network for High-Precise and Well-Interpretable Electrocardiogram Classification

Liu, X.; Liu, X.

10.1101/2024.01.03.573822 — bioengineering — Posted on 2024-01-04

4196 Reinforcement Expectation in the Honey Bee (Apis mellifera): Downshifts in Reinforcement Show Conditioned Inhibition

Mahoney, S.; Hosler, J.; Smith, B. H. H.

10.1101/2024.01.03.574098 — animal behavior and cognition — Posted on 2024-01-04

4197 Thermal energetics of bats of the family Vespertilionidae: an evolutionary approach

Ayala-Berdon, J.; Medina-bello, K. I.; Carballo-Morales, J. D.; Saldana-Vazquez, R. A.; Villalobos, F.

10.1101/2024.01.03.574072 — evolutionary biology — Posted on 2024-01-04

4198 Life stage impact on the human skin ecosystem: lipids and the microbial community

Pagac, M. P.; Davient, B.; Ravikrishnan, A.; Chua, E.; Irudayaswamy, A.; Srinivas, R.; Wearne, S.; Muralidharan, S.; Sridharan, A.; Mohamed Naim, A. N.; Ho, E.; Ng, A.; Kwah, J.; Png, E.; Bendt, A.; Wenk, M.; Torta, F.; Nagarajan, N.; Common, J.; Chong, Y. S.; Tham, E.; Shek, L.; Loo, E.; Chambers, J.; Yew, Y. W.; Loh, M.; Dawson, T.

10.1101/2024.01.03.573871 — microbiology — Posted on 2024-01-04

4199 Comparative phosphoproteome analysis of primary and metastatic uveal melanoma cell lines

Glinkina, K.; Prieto, R. G.; Teunisse, A. F. A. S.; Gelmi, M. C.; Jager, M. J.; Vertegaal, A. C. O.; Jochemsen, A. G.

10.1101/2023.12.06.570407 — cancer biology — Posted on 2024-01-04

4200 Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

Dantzer, C.; Vache, J.; Brunel, A.; Mahouche, I.; Raymond, A.-A.; Dupuy, J.-W.; Petrel, M.; Bioulac-Sage, P.; Perrais, D.; Dugot-Senant, N.; Verdier-Sage, M.; Bessette, B.; Billottet, C.; Moreau, V.

10.1101/2023.10.24.563805 — cancer biology — Posted on 2024-01-04

4201 The molecular basis of Abelson kinase regulation by its αI-helix

Paladini, J.; Maier, A.; Habazettl, J. M.; Hertel, I.; Sonti, R.; Grzesiek, S.

10.1101/2023.10.04.560671 — biophysics — Posted on 2024-01-04

4202 Heat stress impairs centromere structure and segregation of meiotic chromosomes in Arabidopsis

Crhak Khaitova, L.; Mikulkova, P.; Pecinkova, J.; Kalidass, M.; Heckmann, S.; Lermontova, I.; Riha, K.

10.1101/2023.04.19.537519 — plant biology — Posted on 2024-01-04

4203 Membrane protein sequence features direct post-translational insertion

Kalinin, I. A.; Peled-Zehavi, H.; Barshap, A. B. D.; Tamari, S. A.; Weiss, Y.; Nevo, R.; Fluman, N.

10.1101/2023.12.12.571264 — biochemistry — Posted on 2024-01-04

4204 DNAGPT: A Generalized Pre-trained Tool for Multiple DNA Sequence Analysis Tasks

Zhang, D.; Zhang, w.; Zhao, Y.; Zhang, J.; He, B.; Qin, C.; Yao, J.

10.1101/2023.07.11.548628 — genomics — Posted on 2024-01-04

4205 Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent

Korfmann, K.; Sellinger, T. P. P.; Freund, F.; Fumagalli, M.; Tellier, A.

10.1101/2022.09.28.508873 — genetics — Posted on 2024-01-04

4206 Human-level reinforcement learning performance of recurrent neural networks is linked to hyperperseveration, not directed exploration

Tuzsus, D.; Brands, A.; Pappas, I.; Peters, J.

10.1101/2023.04.27.538570 — neuroscience — Posted on 2024-01-04

4207 The receptor-like kinase BIR1 inhibits elicitor-induced plasmodesmata callose deposition and PTI gene expression and requires EDS1 and SOBIR1 to cause dose-dependent cell-death in Arabidopsis

Guzman-Benito, I.; Robinson, C.; Hua, C.; Sede, A. R.; Elvira-Gonzalez, L.; Punzon, I.; Heinlein, M.; Nurnberger, T.; Llave, C.

10.1101/2023.06.23.546234 — plant biology — Posted on 2024-01-04

4208 Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

Wells, S. B.; Rainbow, D.; Mark, M.; Szabo, P. P. A. S.; Ergen, C.; Maceiras, A. R.; Caron, D. P.; Rahmani, E.; Benuck, E.; Amiri, V. V. P.; Chen, D.; Wagner, A.; Howlett, S. K.; Jarvis, L. B.; Elli, K. L.; Kubota, M.; Matsumoto, R.; Mahbubani, K. T.; Saeb-Parsy, K.; Dominguez-Conde, C.; Richardson, L.; Xu, C.; Li, S.; Mamanova, L.; Bolt, L.; Wilk, A.; Teichmann, S. B.; Farber, D. L.; Sims, P. A.; Jones, J. L.; Yosef, N.

10.1101/2024.01.03.573877 — immunology — Posted on 2024-01-04

4209 Mitochondrial reverse electron transport in myeloid cells perpetuates neuroinflammation

Peruzzotti-Jametti, L.; Willis, C. M.; Hamel, R.; Krzak, G.; Reisz, J. A.; Prag, H. A.; Wu, V.; Xiang, Y.; van den Bosch, A.; Nicaise, A. M.; Roth, L.; Bates, G. R.; Huang, H.; Vincent, A. E.; Frezza, C.; Viscomi, C.; Marioni, J. C.; D'Alessandro, A.; Takats, Z.; Murphy, M. P.; Pluchino, S.

10.1101/2024.01.03.574059 — neuroscience — Posted on 2024-01-04

4210 Dependence of Nucleosome Mechanical Stability on DNA Mismatches

Ngo, T. T. M.; Liu, B.; Wang, F.; Basu, A.; Wu, C.; Ha, T.

10.1101/2022.11.21.517409 — biophysics — Posted on 2024-01-03

4211 ExploreTurns: A web tool for the exploration, analysis and retrieval of beta turns and their contexts in proteins; application to beta-bulge loops and helix capping

Newell, N. E.

10.1101/2024.01.01.573820 — bioinformatics — Posted on 2024-01-03

4212 Differential activation of rhodopsin triggers distinct endocytic trafficking and recycling in vivo via differential phosphorylation

Ferng, D.; Sun, W.; Shieh, B.-H.

10.1101/2024.01.03.574057 — cell biology — Posted on 2024-01-03

4213 A PACAP-activated network for secretion requires coordination of calcium influx and calcium mobilization

Chen, X.; Bell, N. A.; Coffman, B. L.; Rabino, A.; Garcia-Mata, R.; Yule, D. I.; Axelrod, D.; Smrcka, A.; Giovannucci, D. R.; Anantharam, A.

10.1101/2024.01.03.574069 — cell biology — Posted on 2024-01-03

4214 Standardized Parts for Activation of Small GTPase Signaling in Living Cells

He, Y.; Faulkner, B. M.; Roberti, M. A.; Bassford, D. K.; Stains, C. I.

10.1101/2024.01.03.574079 — cell biology — Posted on 2024-01-03

4215 A geometric parameterization for beta turns

Newell, N. E.

10.1101/2024.01.01.573818 — molecular biology — Posted on 2024-01-03

4216 TDP 2 modulates the expression of estrogen-responsive oncogenes

Manguso, N.; Kim, M.; Joshi, N.; Al Mahmud, R.; Aldaco, J.; Suzuki, R.; Cortes-Ledesma, F.; Cui, X.; Yamada, S.; Takeda, S.; Giuliano, A. E.; You, S.; Tanaka, H.

10.1101/2022.06.01.494417 — molecular biology — Posted on 2024-01-03

4217 A Genome-Wide CRISPR Screen Identifies Sortilin as the Receptor Responsible for Galectin-1 Lysosomal Trafficking

Donnelly, J.; Kamber, R. A.; Wisnovsky, S.; Roberts, D. S.; Peltan, E. L.; Bassik, M. C.; Bertozzi, C. R.

10.1101/2024.01.03.574113 — molecular biology — Posted on 2024-01-03

4218 Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria

Zhang, L.; Guan, Y.; Cheng, Y. Y.; Cokcetin, N. N.; Bottomley, A.; Robinson, A.; Harry, E.; van Oijen, A. M.; Su, Q. P.; Jin, D.

10.1101/2022.03.29.486198 — microbiology — Posted on 2024-01-03

4219 Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals

Nguyen, V.; Stell, B. M.

10.1101/2024.01.03.574031 — neuroscience — Posted on 2024-01-03

4220 Simultaneous identification of m6A and m5C reveals coordinated RNA modification at single-molecule resolution

10.1101/2022.03.14.484124 — bioinformatics — Posted on 2024-01-03

4221 ElegansBot: Development of equation of motion deciphering locomotion including omega turns of Caenorhabditis elegans

Chung, T.; Chang, I.; Kim, S.

10.1101/2023.09.26.559644 — animal behavior and cognition — Posted on 2024-01-03

4222 Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors

Wang, W.; Xing, J.; Zhang, X.; Liu, H.; Jiang, H.; Xu, C.; Zhao, X.; Hu, Z.

10.1101/2024.01.01.573824 — cell biology — Posted on 2024-01-03

4223 Naive primary neutrophils play a dual role in the tumor microenvironment

Babatunde, K. A.; Datta, R.; Hendikse, N. W.; Ayuso, J. M.; Huttenlocher, A.; Skala, M. C.; Beebe, D. J.; Kerr, S. C.

10.1101/2023.09.15.557892 — cell biology — Posted on 2024-01-03

4224 Morphometrics of the preserved post-surgical hemisphere in pediatric drug-resistant epilepsy

Granovetter, M. C.; Maallo, A. M. S.; Patterson, C.; Glen, D.; Behrmann, M.

10.1101/2023.09.24.559189 — neuroscience — Posted on 2024-01-03

4225 Conflicts are parametrically encoded: initial evidence for a cognitive space view to reconcile the debate of domain-general and domain-specific cognitive control

Yang, G.; Wu, H.; Li, Q.; Liu, X.; Fu, Z.; Jiang, J.

10.1101/2023.02.13.528292 — neuroscience — Posted on 2024-01-03

4226 Conserved auxin signalling synergism through the canonical and ETT-mediated pathways promotes gynoecium development in members of the Brassicaceae

McLaughlin, H. M.; Lü, T.-F.; Natarajan, B.; Ostergaard, L.; Dong, Y.

10.1101/2023.03.02.530771 — plant biology — Posted on 2024-01-03

4227 MapTurns: mapping the structure, H-bonding and contexts of beta turns in proteins

Newell, N. E.

10.1101/2024.01.02.573949 — bioinformatics — Posted on 2024-01-03

4228 GeneMark-ETP: Automatic Gene Finding in Eukaryotic Genomes in Consistency with Extrinsic Data

Bruna, T.; Lomsadze, A.; Borodovsky, M.

10.1101/2023.01.13.524024 — bioinformatics — Posted on 2024-01-03

4229 Cell and tissue-specific glycosylation pathways informed by single-cell transcriptomics

Chrysinas, P.; Venkatesan, S.; Ang, I.; Ghosh, V.; Chen, C.; Neelamegham, S.; Gunawan, R.

10.1101/2023.09.26.559616 — bioinformatics — Posted on 2024-01-03

4230 Germline CpG methylation signatures in the human population inferred from genetic polymorphism

Si, Y.; Kang, H. M.; Zoellner, S.

10.1101/2023.03.24.534151 — genetics — Posted on 2024-01-03

4231 Single-cell measurement of microbial growth rate with Raman microspectroscopy

Caro, T. A.; Kashyap, S.; Brown, G.; Chen, C.; Kopf, S.; Templeton, A.

10.1101/2023.12.16.571966 — microbiology — Posted on 2024-01-03

4232 Antigen non-specific CD8+ T cells accelerate cognitive decline in aged mice following respiratory coronavirus infection

Reagin, K. L.; Lee, R.-L.; Cocciolone, L.; Funk, K. E.

10.1101/2024.01.02.573675 — immunology — Posted on 2024-01-03

4233 Extensive co-regulation of neighbouring genes complicates the use of eQTLs in target gene prioritisation

Tambets, R.; Kolde, A.; Kolberg, P.; Love, M. I.; Alasoo, K.

10.1101/2023.09.29.560109 — genetics — Posted on 2024-01-03

4234 BCG activation of trained immunity is associated with induction of cross reactive COVID-19 antibodies in a BCG vaccinated population.

Iqbal, N. T.; Ahmed, K.; Sattar, T.; Aziz, F.; Hussain, R.

10.1101/2024.01.02.573408 — immunology — Posted on 2024-01-03

4235 Measuring conformational equilibria in allosteric proteins with time-resolved tmFRET

Zagotta, W. N.; Evans, E. G.; Eggan, P.; Tessmer, M.; Shaffer, K. D.; Petersson, J.; Stoll, S.; Gordon, S. E.

10.1101/2023.10.09.561594 — biophysics — Posted on 2024-01-03

4236 An RNAi screen for conserved kinases that enhance microRNA activity after dauer in C. elegans

Roka Pun, H.; Karp, X.

10.1101/2023.10.17.562753 — genetics — Posted on 2024-01-03

4237 Genetic drift drives faster-Z evolution in the salmon louse Lepeophtheirus salmonis

Mongue, A. J.; Baird, R. B.

10.1101/2023.12.20.572545 — evolutionary biology — Posted on 2024-01-03

4238 AT-biased genotypes of Ophiocordyceps sinensis may not be generated through RIP mutagenesis in a single genome of GC-biased Hirsutella sinensis

Li, X.-Z.; Li, Y.-l.; Wang, Y.-N.; Zhu, J.-S.

10.1101/2022.12.09.519819 — molecular biology — Posted on 2024-01-03

4239 A nucleoid-associated protein is involved in the emergence of antibiotic resistance by promoting the frequent exchange of the replicative DNA polymerase in M. smegmatis

Ng, W. L.; Rego, E. H.

10.1101/2023.06.12.544663 — microbiology — Posted on 2024-01-03

4240 Loss of Bcl6 transcriptionally alters classical dendritic cells and diminishes T follicular helper cell and Th17-inducing cDC2 in mice

Xiao, H.; Ulmert, I.; Bach, L.; Huber, J.; Narasimhan, H.; Kurochkin, I.; Chang, Y.; Holst, S.; Moerbe, U.; Zhang, L.; Schlitzer, A.; Pereira, F.; Schraml, B.; Baumjohann, D.; Lahl, K.

10.1101/2022.08.10.503322 — immunology — Posted on 2024-01-03

4241 Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis

Mennillo, E.; Kim, Y. J.; Lee, G.; Rusu, I.; Patel, R.; Dorman, L. C.; Flynn, E.; Li, S.; Bain, J. L.; Andersen, C.; Rao, A.; Tamaki, S.; Tsui, J.; Shen, A.; Lotstein, M. L.; Rahim, M.; Naser, M.; Bernard-Vazquez, F.; Eckalbar, W.; Cho, S.-j.; Beck, K.; El-Nachef, N.; Lewin, S.; Selvig, D. R.; Terdiman, J. P.; Mahadevan, U.; Oh, D. Y.; Fragiadakis, G. K.; Pisco, A.; Combes, A.; Kattah, M. G.

10.1101/2023.01.21.525036 — immunology — Posted on 2024-01-03

4242 Visual looming is a primitive for human emotion

Thieu, M. K. N.; Ayzenberg, V.; Lourenco, S. F.; Kragel, P. A.

10.1101/2023.08.29.555380 — neuroscience — Posted on 2024-01-03

4243 Recurrent impairments in visual perception and place avoidance across autism models are causally linked in the haploinsufficiency model of intellectual disability Setd5

Burnett, L. E.; Koppensteiner, P.; Symonova, O.; Masson, T.; Vega-Zuniga, T.; Contreras, X.; Ruelicke, T.; Shigemoto, R.; Novarino, G.; Joesch, M.

10.1101/2022.10.11.511691 — neuroscience — Posted on 2024-01-03

4244 BrainBeats: an open-source EEGLAB plugin to jointly analyze EEG and cardiovascular (ECG/PPG) signals

Cannard, C.; Wahbeh, H.; Delorme, A.

10.1101/2023.06.01.543272 — neuroscience — Posted on 2024-01-03

4245 Multi-day Neuron Tracking in High Density Electrophysiology Recordings using EMD

Yuan, A. X.; Colonell, J. I.; Lebedeva, A.; Okun, M.; Charles, A.; Harris, T. D.

10.1101/2023.08.03.551724 — neuroscience — Posted on 2024-01-03

4246 Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years

Finley, A. J.; Angus, D. J.; Knight, E.; van Reekum, C. M.; Lachman, M. E.; Davidson, R. J.; Schaefer, S. M.

10.1101/2023.07.17.549371 — neuroscience — Posted on 2024-01-03

4247 A Practical Approach for Targeting Structural Variants Genome-wide in Plasma Cell-free DNA

Murata, M. M.; Igari, F.; Urbanowicz, R.; Mouakkad, L.; Kim, S.; Chen, Z.; Di Vizio, D.; Posadas, E. M.; Giuliano, A. E.; Tanaka, H.

10.1101/2023.10.25.564058 — cancer biology — Posted on 2024-01-03

4248 Rapid and specific detection of single nanoparticles and viruses in microfluidic laminar flow via confocal fluorescence microscopy

Drori, P.; Mouhadeb, O.; Munoz, G. G. M.; Razvag, Y.; Alcalay, R.; Klocke, P.; Cordes, T.; Zahavy, E.; Lerner, E.

10.1101/2023.12.31.573251 — biophysics — Posted on 2024-01-03

4249 Long-distance tmFRET using bipyridyl- and phenanthroline-based ligands

Gordon, S. E.; Evans, E. G.; Otto, S. C.; Tessmer, M.; Shaffer, K. D.; Gordon, M. T.; Petersson, J.; Stoll, S.; Zagotta, W. N.

10.1101/2023.10.09.561591 — biophysics — Posted on 2024-01-03

4250 A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture

Attenborough, T.; Rawlinson, K. A.; Soria, C. L. D.; Ambridge, K.; Sankaranarayanan, G.; Graham, J.; Cotton, J. A.; Doyle, S. R.; Rinaldi, G.; Berriman, M.

10.1101/2023.03.27.533868 — genomics — Posted on 2024-01-03

4251 Polymorphism-aware models in RevBayes: Species trees, disentangling Balancing Selection and CG-biased gene conversion

Braichenko, S.; Borges, R.; Kosiol, C.

10.1101/2023.12.11.571102 — evolutionary biology — Posted on 2024-01-03

4252 Single nucleus transcriptome of a "Super RV" shows increased insulin and angiogenesis signaling

Turaga, D.; Li, X.; Zhao, Y.; Tsai, C.-R.; Moreira, A.; Hickey, E.; Adachi, I.; Martin, J. F.

10.1101/2023.11.28.569092 — developmental biology — Posted on 2024-01-03

4253 Nance-Horan-Syndrome-like 1b controls mesodermal cell migration by regulating protrusion and actin dynamics during zebrafish gastrulation.

Escot, S.; Elouin, A.; Mellottee, L.; David, N. B.

10.1101/2023.01.28.526006 — cell biology — Posted on 2024-01-03

4254 Premature endocycling of Drosophila follicle cells causes pleiotropic defects in oogenesis

Herriage, H. C.; Calvi, B. R.

10.1101/2023.10.10.561736 — cell biology — Posted on 2024-01-03

4255 Caspase-1 activates gasdermin A in non-mammals

Billman, Z. P.; Kovacs, S. B.; Wei, B.; Kang, K.; Cisse, O. H.; Miao, E. A.

10.1101/2023.09.28.559989 — immunology — Posted on 2024-01-03

4256 Cyclic nucleotide-induced bidirectional long-term synaptic plasticity in Drosophila mushroom body

Yamada, D.; Davidson, A. M.; Hige, T.

10.1101/2023.09.28.560058 — neuroscience — Posted on 2024-01-03

4257 The kpc-1 3'UTR facilitates dendritic transport and translation of mRNAs for dendrite arborization of a mechanosensory neuron important for male courtship

Shih, M.; Zou, Y.; Ferreira, T.; Suzuki, N.; Kim, E.; Chuang, C.-F.; Chang, C.

10.1101/2021.08.03.453128 — neuroscience — Posted on 2024-01-03

4258 Sensory-memory interactions via modular structure explain errors in visual working memory

Yang, J.; Zhang, H.; Lim, S.

10.1101/2023.11.09.566396 — neuroscience — Posted on 2024-01-03

4259 Investigation of Biomedical Cell Image Cryptography Based on RC4 Technique

Jiang, S.; Kumar, E.

10.1101/2023.12.29.573618 — bioengineering — Posted on 2024-01-03

4260 Investigation of Two-Component Hydrogel System for the Tissue Regeneration from Simulation

Jiang, S.; Kumar, E.

10.1101/2023.12.28.573564 — biochemistry — Posted on 2024-01-03

4261 Disruption of consciousness depends on insight in OCD and on positive symptoms in schizophrenia

Tumkaya, S.; Yucens, B.; Gunduz, M.; Maheu, M.; Berkovitch, L.

10.1101/2024.01.02.571832 — neuroscience — Posted on 2024-01-03

4262 EryDB: a transcriptomic profile database for erythropoiesis and erythroid-related diseases

Zheng, G.; Wu, S.; Zhang, Z.; Xin, Z.; Zhang, L.; Zhao, S.; Wu, J.; Liu, Y.; Li, M.; Ruan, X.; Bao, Y.; Qu, H.; Fang, X.

10.1101/2023.12.22.572961 — bioinformatics — Posted on 2024-01-03

4263 VLP-Based Model for Study of Airborne Viral Pathogens

Caffrey, M.; Jayakumar, N.; Caffrey, V.; Anirudan, V.; Rong, L.; Paprotny, I.

10.1101/2024.01.03.574055 — molecular biology — Posted on 2024-01-03

4264 RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

Huang, F.; Dai, Z.; Yu, J.; Wang, K.; Chen, C.; Chen, D.; Zhang, J.; Zhao, J.; Zhang, W.; Qi, Y.; Wang, Y.

10.1101/2024.01.03.574004 — cancer biology — Posted on 2024-01-03

4265 Integrated analysis and systematic characterization of the regulatory network for human germline development

Gu, Y.; Chen, J.; Wang, Z.; Li, Z.; Xiao, X.; Shao, Q.; Xiao, Y.; Liu, W.; Xie, S.; Ye, Y.; Jiang, J.; Xiao, X.; Yu, Y.; Jin, M.; Young, R.; Hou, L.; Chen, D.

10.1101/2024.01.03.574034 — developmental biology — Posted on 2024-01-03

4266 Experimental evaluation of Eastern box turtle (Terrapene carolina carolina) detectability in visual search surveys

Heinle, W. F.; Beswick, N.; Wapman, E.; Royle, J.

10.1101/2024.01.02.572695 — ecology — Posted on 2024-01-03

4267 Sequence-based modelling of bacterial genomes enables accurate antibiotic resistance prediction

Wiatrak, M.; Weimann, A.; Dinan, A. M.; Brbic, M.; Floto, R. A.

10.1101/2024.01.03.574022 — microbiology — Posted on 2024-01-03

4268 Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3-/- mice

Weiss, F. D.; Alvarez, Y.; Sahu, A.; Shakeri, F.; Lee, H. E.; Gellner, A.-K.; Buness, A.; Latz, E.; Meissner, F.

10.1101/2024.01.03.573991 — immunology — Posted on 2024-01-03

4269 Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

Santollani, L.; Zhang, Y. J.; Maiorino, L.; Palmeri, J. R.; Stinson, J. A.; Duhamel, L. R.; Qureshi, K.; Suggs, J. R.; Porth, O. T.; Pinney, W.; Al Msari, R.; Wittrup, K. D.; Irvine, D. J.

10.1101/2024.01.03.573641 — immunology — Posted on 2024-01-03

4270 Kernels of Motor Memory Formation: Temporal Generalization in Bimanual Adaptation

Howard, I. S.; Franklin, S.; Franklin, D. W.

10.1101/2024.01.03.574029 — neuroscience — Posted on 2024-01-03

4271 Dynamical constraints on neural population activity

Oby, E. R.; Degenhart, A. D.; Grigsby, E. M.; Motiwala, A.; McClain, N. T.; Marino, P. J.; Yu, B.; Batista, A. P.

10.1101/2024.01.03.573543 — neuroscience — Posted on 2024-01-03

4272 Non-genetic adaptation by collective migration

Vo, L.; Avgidis, F.; Mattingly, H.; Balasubramanian, R.; Shimizu, T. S.; Kazmierczak, B. I.; Emonet, T.

10.1101/2024.01.02.573956 — systems biology — Posted on 2024-01-03

4273 Single-cell RNA-seq analysis profiling characterizes differences in cell composition and physiology between normal tissue, treatment-naive, and cisplatin-treated ovarian cancer

Guo, F.; Yang, Z.; Sehouli, J.; Kaufmann, A.

10.1101/2024.01.02.573967 — cancer biology — Posted on 2024-01-03

4274 Targeting transcription factors through an IMiD independent zinc finger domain

Liu, B. H.; Liu, M.; Radhakrishnan, S.; Jaladanki, C. K.; Gao, C.; Tang, J.; Kumari, K.; Go, M. L.; Vu Le, K. A.; Seo, H.-S.; Song, K.; Tian, X.; Li, F.; Tan, J.; Arthanari, H.; Qi, J.; Dhe-Paganon, S.; Fan, H.; Tenen, D. G.; Li, C.

10.1101/2024.01.03.574032 — cancer biology — Posted on 2024-01-03

4275 SAXS/MC studies of the mixed-folded protein Cdt1 reveal monomeric, folded over conformations

Smith, K. P.; Chakravarthy, S.; Rahi, A.; Chakraborty, M.; Vosberg, K. M.; Tonelli, M.; Plach, M. G.; Grigorescu, A.; Curtis, J. E.; Varma, D.

10.1101/2024.01.03.573975 — biophysics — Posted on 2024-01-03

4276 Novel metagenomics analysis suggests a Vibrio species is associated with stony coral tissue loss disease

Heinz, J. M.; Sommer, M.; Rosales, S. M.; Lu, J.; Huebner, L. K.; Salzberg, S. L.

10.1101/2024.01.02.573916 — bioinformatics — Posted on 2024-01-03

4277 PCA-Plus: Enhanced principal component analysis with illustrative applications to batch effects and their quantitation

Zhang, N.; Casasent, T. D.; Casasent, A. K.; Kumar, S. V.; Wakefield, C.; Broom, B. M.; Weinstein, J. N.; Akbani, R.

10.1101/2024.01.02.573793 — bioinformatics — Posted on 2024-01-03

4278 A Bag-Of-Motif Model Captures Cell States at Distal Regulatory Sequences

Cornejo, P.; Zhang, X.; Louis, L.; Yang, Y.; Li, Z.; Humphreys, D. T.; Wong, E. S.

10.1101/2024.01.03.574012 — bioinformatics — Posted on 2024-01-03

4279 Combinatorial prediction of therapeutic perturbations using causally-inspired neural networks

Gonzalez, G.; Herath, I.; Veselkov, K.; Bronstein, M.; Zitnik, M.

10.1101/2024.01.03.573985 — bioinformatics — Posted on 2024-01-03

4280 SYNTERUPTOR: mining genomic islands for non-classical specialised metabolite gene clusters

Haas, D.; Barba, M.; Vicente, C. M.; Nezbedova, S.; Garenaux, A.; Bury-Mone, S.; Lorenzi, J.-N.; Hotel, L.; Laureti, L.; Thibessard, A.; Le Goff, G.; Ouazzani, J.; Leblond, P.; Aigle, B.; Pernodet, J.-L.; Lespinet, O.; Lautru, S.

10.1101/2024.01.03.573040 — bioinformatics — Posted on 2024-01-03

4281 Tumor relapse-free survival prognosis related consistency between cancer tissue and adjacent normal tissue in drug repurposing for solid tumor via connectivity map

Ma, W.; Li, J.; Xiong, M.; Hao, M.; Li, D.; Qiao, Y.

10.1101/2024.01.03.573997 — bioinformatics — Posted on 2024-01-03

4282 Simultaneous identification of m6A and m5C reveals coordinated RNA modification at single-molecule resolution

10.1101/2022.03.14.484124 — bioinformatics — Posted on 2024-01-03

4283 MapTurns: mapping the structure, H-bonding and contexts of beta turn in proteins

Newell, N.

10.1101/2024.01.02.573949 — bioinformatics — Posted on 2024-01-03

4284 Unraveling Alternative Splicing Regulations in Seriola dumerili Underlying Their Responses to Ambient Salinity Oscillations

Zhao, C.; Zhang, P.; Liu, Y.; Yang, Y.

10.1101/2024.01.03.574042 — bioinformatics — Posted on 2024-01-03

4285 "Hitting Two Birds with One Stone" Design of Intestinal Integrin-Targeting and Redox Homeostasis-Regulating Oral Nanotherapy for Ulcerative Colitis

Huang, L.; Hu, W.; Huang, L. Q.; Zhou, Q. X.; Song, Z. Y.; Tao, H. Y.; Xu, B.; Zhang, C. Y.; Wang, Y.; Xing, X.-H.

10.1101/2024.01.02.573980 — bioengineering — Posted on 2024-01-03

4286 Fast and lightweight cell atlas approximations across organs and organisms

Xu, Y.; Ahn, J.; Zanini, F.

10.1101/2024.01.03.573994 — cell biology — Posted on 2024-01-03

4287 Assessment of autophagy in Leishmania parasites

Onwah, S. S.; Uzonna, J. E.; Ghavami, S.

10.1101/2024.01.03.574013 — cell biology — Posted on 2024-01-03

4288 A geometric parameterization for beta turns

Newell, N. E.

10.1101/2024.01.01.573818 — molecular biology — Posted on 2024-01-03

4289 Protocols for Multi-Scale Molecular Dynamics Simulations: A Comparative Study for Intrinsically Disordered Amyloid Beta in Amber & Gromacs on CPU & GPU

Smardz, P.; Anila, M. M.; Rogowski, P.; Rozycki, B.; Li, M. S.; Krupa, P.

10.1101/2023.10.24.563575 — molecular biology — Posted on 2024-01-03

4290 The proximity-based protein interaction landscape of the transcription factor p65 NF-kappaB/RELA and its gene-regulatory logics

Kracht, M.; Leib, L.; Juli, J.; Juirda, L. M.; Meier-Soelch, J.; Mayr-Buro, C.; Schmitz, M. L.; Heylmann, D.; Weber, A.; Papantonis, A.; Bartkuhn, M.; Wilhelm, J.; Linne, U.

10.1101/2024.01.03.574021 — molecular biology — Posted on 2024-01-03

4291 Determination and characterization of papillomaviurs and parvovirus causing mass mortality of Chinese tongue sole (Cynoglossus semilaevis) in China

Xue, S.; Liu, X.; Liu, Y.; Lu, C.; Jia, L.; Yu, Y.; Liu, H.; Yang, S.; Zeng, Z.; Li, H.; Qin, J.; Wang, Y.; Sun, J.

10.1101/2024.01.02.573988 — microbiology — Posted on 2024-01-03

4292 Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene Expression

Liao, Y.; Yan, J.; Beri, N. R.; Roth, L. G.; Cesarman, E.; Gewurz, B.

10.1101/2024.01.02.573986 — microbiology — Posted on 2024-01-03

4293 Single missense mutations in Vi capsule synthesis genes confer hypervirulence to Salmonella Typhi

Lee, G. Y.; Song, J.

10.1101/2023.12.28.573590 — microbiology — Posted on 2024-01-03

4294 Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

10.1101/2024.01.03.573877 — immunology — Posted on 2024-01-03

4295 Threshold-Free Network-Oriented Statistics in Neuroscience

Hao, Z.; Wang, P.; Xia, X.; Pan, Y.; Dou, W.

10.1101/2024.01.03.574016 — neuroscience — Posted on 2024-01-03

4296 An opponent striatal circuit for distributional reinforcement learning

Lowet, A. S.; Zheng, Q.; Meng, M.; Matias, S.; Drugowitsch, J.; Uchida, N.

10.1101/2024.01.02.573966 — neuroscience — Posted on 2024-01-03

4297 Growth in early infancy drives optimal brain functional connectivity which predicts cognitive flexibility in later childhood

Bulgarelli, C.; Blasi, A.; McCann, S.; Milosavljevic, B.; Ghillia, G.; Mbye, E.; Touray, E.; Fadera, T.; Acolatse, L.; Moore, S. E.; Lloyd-Fox, S.; Elwell, C. E.; Eggebrecht, A. T.

10.1101/2024.01.02.573930 — neuroscience — Posted on 2024-01-03

4298 Spatiotemporal models for multisensory integration

Parise, C. V.

10.1101/2023.12.29.573621 — neuroscience — Posted on 2024-01-03

4299 A 'double-edged' role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs

Notartomaso, S.; Antenucci, N.; Mazzitelli, M.; Rovira, X.; Boccella, S.; Ricciardi, F.; Liberatore, F.; Gomez-Santacana, X.; Imbriglio, T.; Cannella, M.; Zussy, C.; Luongo, L.; Maione, S.; Goudet, C.; Battaglia, G.; Llebaria, A.; Nicoletti, F.; Neugebauer, V.

10.1101/2024.01.02.573945 — neuroscience — Posted on 2024-01-03

4300 Medial prefrontal cortex suppresses reward-seeking behavior with risk of positive punishment by reducing sensitivity to reward

Nishio, M.; Kondo, M.; Eriko, Y.; Matsuzaki, M.

10.1101/2024.01.03.573768 — animal behavior and cognition — Posted on 2024-01-03

4301 Plasticity and evolutionary dynamics of alternative RNA splicing

Zhang, W.; Guenther, A.; Gao, Y.; Ullrich, K. K.; Huettel, B.; Tautz, D.

10.1101/2024.01.03.573993 — genomics — Posted on 2024-01-03

4302 Chromosome Structure II: Stem-loops and circle-loops

Ke, W.; Fujioka, M.; Schedl, P.; Jaynes, J. B.

10.1101/2024.01.02.573928 — genetics — Posted on 2024-01-03

4303 Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

Isotani, R.; Igarashi, M.; Miura, M.; Naruse, K.; Kuranami, S.; Yamauchi, T.

10.1101/2024.01.02.573853 — cell biology — Posted on 2024-01-03

4304 Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition

Tenge, V. R.; Ayyar, B. V.; Ettayebi, K.; Crawford, S. E.; Shen, Y.-T.; Neill, F. H.; Atmar, R. L.; Estes, M. K.

10.1101/2024.01.02.573926 — microbiology — Posted on 2024-01-03

4305 Generative whole-brain dynamics models from healthy subjects predict functional alterations in stroke at the level of individual patients

Idesis, S.; Allegra, M.; Vohryzek, J.; Perl, Y. S.; Metcalf, N.; Griffis, J. C.; Corbetta, M.; Shulman, G.; Deco, G.

10.1101/2024.01.02.573878 — neuroscience — Posted on 2024-01-03

4306 A combinatory genetic strategy for targeting neurogliaform neurons in the mouse basolateral amygdala

Ozsvar, A.; Sieburg, M. C.; Sietam, M. D.; Hou, W.-H.; Capogna, M.

10.1101/2024.01.03.573867 — neuroscience — Posted on 2024-01-03

4307 Intensity mismatch asymmetry in tinnitus: in which direction should participants pay attention?

Yukhnovich, E. A.; Alter, K.; Sedley, W.

10.1101/2024.01.02.573912 — neuroscience — Posted on 2024-01-03

4308 Suppression of epileptic seizures by transcranial activation of K+-selective channelrhodopsin

Duan, X.; Zhang, C.; Wu, Y.; Ju, J.; Xu, Z.; Li, X.; Liu, Y.; Ohdah, S.; Constantin, O. M.; Lu, Z.; Wang, C.; Chen, X.; Gee, C. E.; Nagel, G.; Hou, S.-T.; Gao, S.; Song, K.

10.1101/2024.01.03.573747 — neuroscience — Posted on 2024-01-03

4309 Epigenetic Modulation to perturb the SYNGAP1 Intellectual Disability (ID) that ameliorates synaptic and behavioural deficits

Singh, A. K.; Joshi, I.; Reddy, N. M. N.; Purushotham, S. S.; Eswaramoorth, M.; Vasudevan, M.; Banerjee, S.; Clement, J. P.; Kundu, T. K.

10.1101/2024.01.03.574003 — neuroscience — Posted on 2024-01-03

4310 Dissecting the heat stress altering immune responses and skin microbiota in fish in a recirculating aquaculture system in Singapore

Ng, T. H.; M, S.; Chew, X. Z.; Nair D/O Madhaven, T.; Chow, J. W.; Low, A.; Seedorf, H.; Bastos Gomes, G.

10.1101/2024.01.02.573918 — systems biology — Posted on 2024-01-03

4311 3D-Printable Non-invasive Head Immobilization System for Non-Human Primates

Shahbazi, E.; Swedan, T.; Ma, T.; Lafer-Sousa, R.; Azadi, R.; Nguyen, D.; Ryan, A.; Afraz, A.

10.1101/2024.01.02.573832 — physiology — Posted on 2024-01-03

4312 Inhibiting YAP1 reduced abdominal aortic aneurysm formation by suppressing adventitial fibroblast phenotype transformation and migration

Xie, C.; Hu, Y.; Yin, Z.

10.1101/2024.01.02.573973 — pathology — Posted on 2024-01-03

4313 A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques

Fresnais, L.; Perin, O.; Riu, A.; Grall, R.; Ott, A.; Fromenty, B.; Gallardo, J. C.; Stingl, M.; Frainay, C.; Jourdan, F.; Poupin, N.

10.1101/2023.06.30.547200 — bioinformatics — Posted on 2024-01-03

4314 Insights into Yeast Response to Chemotherapeutic Agent through Time Series Genome-Scale Metabolic Models

Karabekmez, M. E.

10.1101/2024.01.02.573982 — bioengineering — Posted on 2024-01-03

4315 Antigen density and applied force control enrichment of nanobody-expressing yeast cells in microfluidics

Sanicas, M.; Torro, R.; Limozin, L.; Chames, P.

10.1101/2024.01.03.574015 — bioengineering — Posted on 2024-01-03

4316 Effects of long-term high dose aspartame on body mass, bone strength, femoral geometry, and microbiota composition in a young and aged cohort of male and female mice

Cyphert, E. L.; Liu, C.; Morales, A. L.; Nixon, J. C.; Blackford, E.; Garcia, M.; Cevallos, N.; Turnbaugh, P. J.; Brito, I. L.; Booth, S. L.; Hernandez, C. J.

10.1101/2024.01.02.573970 — bioengineering — Posted on 2024-01-03

4317 Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168

Ai, H.; Tong, Z.; Deng, Z.; Shi, Q.; Tao, S.; Liang, J.; Sun, M.; Wei, X.; Zheng, Q.; Liang, L.; Li, J.-B.; Gao, S.; Tian, C.; Liu, L.; Pan, M.

10.1101/2024.01.02.573964 — biochemistry — Posted on 2024-01-03

4318 Tracing India's Canine Heritage through SNP-Based Haplotype Identification

Singh, D.; Mahajan, S. K.; Kashyap, N.; Mukhopadhyay, C. S.

10.1101/2024.01.02.573915 — evolutionary biology — Posted on 2024-01-03

4319 Background food influences rate of encounter and efficacy of rodenticides in wild house mice

Brown, P. R.; Henry, S.; Hinds, L. A.; Robinson, F.; Duncan, R. P.; Ruscoe, W. A.

10.1101/2024.01.02.573962 — ecology — Posted on 2024-01-03

4320 The opossum and other didelphids in the cultures of Costa Rican society and indigenous peoples: an approach to ecology and conservation

Azofeifa Romero, Y.; Duran Alvarado, F. J.

10.1101/2024.01.02.573906 — ecology — Posted on 2024-01-03

4321 Editing of endogenous tubulins reveals varying effects of tubulin posttranslational modifications on axonal growth and regeneration

Lu, Y.-M.; Yan, S.; Ti, S.-C.; Zheng, C.

10.1101/2024.01.02.573937 — cell biology — Posted on 2024-01-03

4322 EI24-RTRAF interaction represses Nox4 translation, vital for redox balance and insulin production

Pei, X.; Wang, Z.; He, W.; Li, S.; Lan, Y.; Yuan, L.; Xu, P.

10.1101/2024.01.02.573947 — cell biology — Posted on 2024-01-03

4323 The Nrf2/Id2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging

Xu, M.; Wei, X.; Wang, J.; Li, Y.; Huang, Y.; Cheng, A.; He, F.; Zhang, L.; Zhang, C.; Liu, Y.

10.1101/2024.01.02.573972 — molecular biology — Posted on 2024-01-03

4324 FveDAD2 negatively regulates branch crowns by affecting abscisic acid metabolism through FveHB7 in woodland strawberry

Sun, H.; Zhang, J.; Li, W.; Wang, Y.; Zhang, Z.

10.1101/2024.01.02.573951 — molecular biology — Posted on 2024-01-03

4325 Neu5Gc binding loss of subtype H7 influenza A virus facilitates adaptation to gallinaceous poultry following transmission from waterbirds but restricts spillback

Guan, M.; Deliberto, T. J.; Feng, A.; Zhang, J.; Li, T.; Wang, S.; Li, L.; Killian, M. L.; Praena, B.; Giri, E.; Deliberto, S. T.; Hang, J.; Olivier, A.; Torchetti, M. K.; Tao, Y. J.; Parrish, C.; Wan, X.-F.

10.1101/2024.01.02.573990 — microbiology — Posted on 2024-01-03

4326 Steppe lemmings and Chinese hamsters as new potential animal models for the study of the leishmania subgenus Mundinia (Kinetoplastida: Trypanosomatidae)

Becvar, T.; Vojtkova, B.; Pacakova, L.; Vomackova Kykalova, B.; Ticha, L.; Volf, P.; Sadlova, J.

10.1101/2024.01.02.573987 — microbiology — Posted on 2024-01-03

4327 Biofilm formation and maize root-colonization of seed-endophytic Bacilli isolated from native maize landraces

Gastelum, G.; Angeles-Morales, A.; Arellano-Wattenbarger, G.; Coronado, Y.; Guevara-Hernandez, E.; Rocha, J.

10.1101/2024.01.02.573954 — microbiology — Posted on 2024-01-03

4328 Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection

Zou, Z.; Obernuefemann, C.; Singh, P.; Pinkner, J.; Xu, W.; Nye, T.; Dodson, K.; Almqvist, F.; Hultgren, S.; Caparon, M.

10.1101/2024.01.02.573960 — microbiology — Posted on 2024-01-03

4329 TIR domains produce histidine-ADPR conjugates as immune signaling molecules in bacteria

Sabonis, D.; Avraham, C.; Lu, A.; Herbst, E.; Silanskas, A.; Leavitt, A.; Yirmiya, E.; Zaremba, M.; Amitai, G.; Kranzusch, P. J.; Sorek, R.; Tamulaitiene, G.

10.1101/2024.01.03.573942 — microbiology — Posted on 2024-01-03

4330 Metabolomics unveiled the impact of alterations in nucleotide glucose metabolism on palmitic acid-induced TLR4 activation in THP-1 macrophages

Wu, N.; Ran, X.; Wang, J.; Wang, P.; Li, L.; She, Y.; Luo, Y.; Li, X.; Jia, Y.; Huang, Y.

10.1101/2024.01.02.573974 — immunology — Posted on 2024-01-03

4331 The asymmetric transfers of visual perceptual learning determined by the stability of geometrical invariants

Yang, Y.; Zhuo, Y.; Zuo, Z.; Zhou, T.; Chen, L.

10.1101/2024.01.02.573923 — neuroscience — Posted on 2024-01-03

4332 Distinct profiles of tinnitus and hyperacusis in intensity deviant responses and auditory evoked potentials

Yukhnovich, E. A.; Alter, K.; Sedley, W.

10.1101/2024.01.02.573726 — neuroscience — Posted on 2024-01-03

4333 The Neuron as a Direct Data-Driven Controller

Moore, J.; Genkin, A.; Tournoy, M.; Pughe-Sanford, J.; de Ruyter van Steveninck, R. R.; Chklovskii, D. B.

10.1101/2024.01.02.573843 — neuroscience — Posted on 2024-01-03

4334 Autotrophic growth of E. coli is achieved by a small number of genetic changes

Ben Nissan, R.; Milshtein, E.; Pahl, V.; de Pins, B.; Jona, G.; Levi, D.; Yung, H.; Nir, N.; Ezra, D.; Gleizer, S.; Link, H.; Noor, E.; Milo, R.

10.1101/2023.06.03.543535 — synthetic biology — Posted on 2024-01-03

4335 A Unified Approach to Investigating 4 dpf Zebrafish Larval Behaviour through a Standardised Light/Dark Assay

Hillman, C. S.; Kearn, J.; Parker, M. O.

10.1101/2023.11.23.568441 — animal behavior and cognition — Posted on 2024-01-03

4336 E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled family members

Bugter, J. M.; van Kerkhof, P.; Janssen, E.; Tran Ngoc Minh, T.; Iglesias van Montfort, D.; Jamieson, C.; Jordens, I.; Maurice, M. M.

10.1101/2023.11.23.568206 — cell biology — Posted on 2024-01-03

4337 Methylome-wide association studies of traumatic injury identifies differential DNA methylation of synaptic plasticity and GABAergic-signalling.

Brown, J.; Marshall, S.; Walker, R.; Campbell, A.; Hayward, C.; McIntosh, A. M.; Evans, K. L.; Thomson, P. A.

10.1101/2023.11.13.566835 — genomics — Posted on 2024-01-03

4338 Atoh1 is required for the formation of lateral line electroreceptors and hair cells, whereas Foxg1 represses an electrosensory fate.

Minarik, M.; Campbell, A. S.; Franek, R.; Vazacova, M.; Havelka, M.; Gela, D.; Psenicka, M.; Baker, C. V. H.

10.1101/2023.04.15.537030 — developmental biology — Posted on 2024-01-03

4339 Travelling waves or sequentially activated discrete modules: mapping the granularity of cortical propagation

Orsher, Y.; Rom, A.; Perel, R.; Lahini, Y.; Blinder, P.; Shein-Idelson, M.

10.1101/2023.08.27.552978 — neuroscience — Posted on 2024-01-03

4340 Tuning of cortical color mechanism revealed using steady-state visually evoked potentials

Watts, D. J.; Rozman, A.; Somers, L. P.; Günel, B.; Racey, C.; Barnes, K. L.; Bosten, J. M.

10.1101/2023.12.10.570997 — neuroscience — Posted on 2024-01-03

4341 Self-supervision advances morphological profiling by unlocking powerful image representations

Kim, V.; Adaloglou, N.; Osterland, M.; Morelli, F.; Halawa, M.; Koenig, T.; Gnutt, D.; Zapata, P. A. M.

10.1101/2023.04.28.538691 — bioinformatics — Posted on 2024-01-03

4342 Biologically informed NeuralODEs for genome-wide regulatory dynamics

Hossain, I.; Fanfani, V.; Fischer, J.; Quackenbush, J.; Burkholz, R.

10.1101/2023.02.24.529835 — genomics — Posted on 2024-01-03

4343 Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER

Jeremy, Y. C.; Tay, F.; Bennion, R. E.; Loss, O.; Maignel, J.; Pons, L.; Foster, K.; Beard, M.; Bard, F. A.

10.1101/2023.10.17.562749 — cell biology — Posted on 2024-01-03

4344 Bilayer charge asymmetry and oil residues destabilize membranes upon poration

Leomil, F.; Stephan, M.; Pramanik, S.; Riske, K.; Dimova, R.

10.1101/2023.02.03.526964 — biophysics — Posted on 2024-01-03

4345 TALEN-induced contraction of CTG trinucleotide repeats in myotonic dystrophy type 1 cells

Betemps, L.; Descorps-Declere, S.; Frenoy, O.; Poggi, L.; Mosbach, V.; Tome, S.; Viterbo, D.; Klein, A.; Ma, L.; Lameiras, S.; Cokelaer, T.; Monot, M.; Dumas, B.; Gourdon, G.; Furling, D.; Richard, G.-F.

10.1101/2023.10.14.562330 — genomics — Posted on 2024-01-03

4346 Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

Sur, S.; Kerwin, M.; Pineda, S.; Sansanwal, P.; Sigdel, T. K.; Sirota, M.; Sarwal, M. M.

10.1101/2022.05.13.491826 — cell biology — Posted on 2024-01-03

4347 Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories

Wuestefeld, A.; Baumeister, H.; Adams, J. N.; de Flores, R.; Hodgetts, C.; Mazloum-Farzaghi, N.; Olsen, R. K.; Puliyadi, V.; Tran, T. T.; Bakker, A.; Canada, K. L.; Dalton, M. A.; Daugherty, A. M.; La Joie, R.; Wang, L.; Bedard, M.; Buendia, E.; Chung, E.; Denning, A.; del Mar Arroyo-Jimenez, M.; Artacho-Perula, E.; Irwin, D. J.; Ittyerah, R.; Lee, E. B.; Lim, S.; del Pilar Marcos-Rabal, M.; Iniguez de Onzono Martin, M. M.; Munoz Lopez, M.; de la Rosa Prieto, C.; Schuck, T.; Trotman, W.; Vela, A.; Yushkevich, P.; Amunts, K.; Augustinack, J. C.; Ding, S.-L.; Insausti, R.; Kedo, O.; Berron, D.;

10.1101/2023.05.24.542054 — neuroscience — Posted on 2024-01-03

4348 Hippocampal subfields and their neocortical interactions during autobiographical memory

Leelaarporn, P.; Dalton, M. A.; Stirnberg, R.; Stoecker, T.; Spottke, A.; Schneider, A.; McCormick, C.

10.1101/2022.05.03.490407 — neuroscience — Posted on 2024-01-03

4349 Stable chromosome configuration and loop-based polarization in animal symbionts

Viehboeck, T.; Weber, P. M.; Krause, N.; Varoquaux, N.; Boccard, F.; Junier, I.; Bulgheresi, S.; Lioy, V. S.

10.1101/2023.12.21.572873 — genomics — Posted on 2024-01-03

4350 Investigation of Two-Component Hydrogel System for the Tissue Regeneration from Simulation

Jiang, S.; Kumar, E.

10.1101/2023.12.28.573564 — biochemistry — Posted on 2024-01-02

4351 Essential Function of Membrane-Bound Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development

Xu, Z.; Wang, Z.; Wang, L.; Qi, Y.

10.1101/2023.06.22.546200 — developmental biology — Posted on 2024-01-02

4352 Comparative reservoir competence of inbred Peromyscus leucopus, C57BL/6J, and C3H/HeN for Borrelia burgdorferi B31

Bourgeois, J.; You, S. S.; Clendenen, L. H.; Shrestha, M.; Petnicki-Ocwieja, T.; Telford, S.; Hu, L.

10.1101/2023.09.28.559638 — microbiology — Posted on 2024-01-02

4353 Diversified repertoire of phage resistance in Klebsiella pneumoniae and bidirectional steering effects impacting antibiotic susceptibility

Nang, S. C.; Lu, J.; Yu, H. H.; Wickremasinghe, H.; Azad, M. A. K.; Han, M.; Zhao, J.; Rao, G.; Bergen, P. J.; Velkov, T.; Sherry, N.; McCarthy, D. T.; Aslam, S.; Schooley, R. T.; Howden, B. P.; Barr, J. J.; Zhu, Y.; Li, J.

10.1101/2022.11.14.516531 — microbiology — Posted on 2024-01-02

4354 Development of a NanoBRET assay for evaluation of 14-3-3σ molecular glues

Vickery, H. R.; Virta, J. M.; Konstantinidou, M.; Arkin, M. R.

10.1101/2023.12.31.573792 — cell biology — Posted on 2024-01-02

4355 Prediction of myeloid malignant cells in Fanconi anemia using machine learning

Flores-Mejia, L. A.; Siliceo-Portugal, P.; Garcia-Quezada, I.; Figueroa, U. J.; Martinez, B. T. B.; Sosa, D.; Osorio, A. R.; Tovar, H.; Frias, S.; Rodriguez, A.

10.1101/2023.12.31.573791 — cancer biology — Posted on 2024-01-02

4356 Comprehensive and accurate genome analysis at scale using DRAGEN accelerated algorithms

Behera, S.; Catreux, S.; Rossi, M.; Troung, S.; Huang, Z.; Ruehle, M.; Visvanath, A.; Parnaby, G.; Roddey, C.; Onuchic, V.; Cameron, D. L.; English, A.; Mehtalia, S.; Han, J.; Mehio, R.; Sedlazeck, F. J.

10.1101/2024.01.02.573821 — genomics — Posted on 2024-01-02

4357 Transcutaneous cervical vagus nerve stimulation improves sensory performance in humans

Jigo, M.; Carmel, J. B.; Wang, Q.; Rodenkirch, C.

10.1101/2023.08.08.552508 — neuroscience — Posted on 2024-01-02

4358 Rare genetic variation in Fibronectin 1 (FN1) protects against APOEe4 in Alzheimer's disease

Bhattarai, P.; Gunasekaran, T. I.; Reyes-Dumeyer, D.; Juelich, D.; Tayran, H.; Yilmaz, E.; Flaherty, D.; Rafael, L.; Martin, M.; Diones, R.; Patricia, R.; Ertekin-Taner, N.; Teich, A. F.; Dennis, D. W.; Scott, H.; Mayeux, R.; Kizil, C.; Vardarajan, B. N.

10.1101/2024.01.02.573895 — genetics — Posted on 2024-01-02

4359 Obesity modifies cell fate plasticity of Pdgfrα-expressing adipocyte progenitors to promote an aberrant mammary microenvironment

Kwende, S. A.; Nuthalapati, P.; Sunder Singh, J. P.; Maity, S.; Ning, D.; Shryock, D. G.; Xuan, Z.; Joshi, P. A.

10.1101/2023.12.28.573587 — cell biology — Posted on 2024-01-02

4360 A New Multiplex TaqMan qPCR for Precise Detection and Quantification of Clavibacter michiganensis in Seeds and Plant Tissue

Brochu, A.-S.; Dumonceaux, T.; Valenzuela, M.; Belanger, R.; Perez-Lopez, E.

10.1101/2023.06.20.545733 — microbiology — Posted on 2024-01-02

4361 Visual looming is a primitive for human emotion

Thieu, M. K. N.; Ayzenberg, V.; Lourenco, S. F.; Kragel, P. A.

10.1101/2023.08.29.555380 — neuroscience — Posted on 2024-01-02

4362 Isolectin B4 (IB4)-conjugated streptavidin for the selective knockdown of proteins in IB4-positive (+) nociceptors

Bogen, O.; Araldi, D.; Sucher, A.; Kober, K.; Ohara, P. T.; Levine, J. D.

10.1101/2023.12.18.572242 — neuroscience — Posted on 2024-01-02

4363 Autism genes converge on microtubule biology and RNA-binding proteins during excitatory neurogenesis

Sun, N.; Teyssier, N.; Wang, B.; Drake, S.; Seyler, M.; Zaltsman, Y.; Everitt, A.; Teerikorpi, N.; Willsey, H. R.; Goodarzi, H.; Tian, R.; Kampmann, M.; Willsey, J.

10.1101/2023.12.22.573108 — systems biology — Posted on 2024-01-02

4364 Thermogenetics for cardiac pacing

Balatskiy, A. V.; Nesterenko, A. M.; Lanin, A. A.; Ovechkina, V. S.; Sabinin, S. S.; Fetisova, E. S.; Moshchenko, A. A.; Jappy, D.; Sokolov, R. A.; Biglova, D. Z.; Solius, G. M.; Solius, E. M.; Korolev, S. V.; Podgorny, O. V.; Kelmanson, I. V.; Rozov, A. V.; Fedotov, A. B.; Bruegmann, T.; Zheltikov, A. M.; Mozhaev, A. A.; Belousov, V. V.

10.1101/2024.01.02.573885 — synthetic biology — Posted on 2024-01-02

4365 Metabolic heterogeneity of colorectal cancer as a prognostic factor: insights gained from fluorescence lifetime imaging

Komarova, A. D.; Sinyushkina, S. D.; Shchechkin, I. D.; Druzhkova, I. N.; Smirnova, S. A.; Terekhov, V. M.; Mozherov, A. M.; Ignatova, N. I.; Nikonova, E. E.; Shirshin, E. A.; Shcheslavskiy, V. I.; Shirmanova, M. V.

10.1101/2024.01.02.573874 — cancer biology — Posted on 2024-01-02

4366 Valine Catabolism Drives Bioenergetic and Lipogenic Fuel Plasticity in Prostate Cancer

Bidgood, C. L.; Philp, L. K.; Rockstroh, A.; Lehman, M.; Nelson, C. C.; Sadowski, M. C.; Gunter, J. H.

10.1101/2024.01.01.573829 — cancer biology — Posted on 2024-01-02

4367 A Lipidomics Approach to Determine the Role of Lipids and its Crosstalk with Autophagy in Lung Cancer Metastasis

da Silva Rosa, S. C.; Alizadeh, J.; Vitorino, R.; Surendran, A.; Ravandi, A.; Kidane, B.; Ghavami, S.

10.1101/2024.01.01.573842 — cancer biology — Posted on 2024-01-02

4368 Single cell lineage tracing reveals subclonal dynamics of anti-EGFR therapy resistance in triple negative breast cancer.

Pellecchia, S.; Franchini, M.; Viscido, G.; Arnese, R.; Gambardella, G.

10.1101/2023.04.04.535588 — cancer biology — Posted on 2024-01-02

4369 Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

Alves, C. J.; Hannah, T.; Sadia, S.; Kolsteeg, C.; Dixon, A.; Wiener, R. J.; Nguyen, H.; Tipping, M. J.; Ladeira, J. S.; Franklin, P. F. d. C.; Dutra de Nigro, N. d. P.; Dias, R. A.; Capriles, P. V. Z.; Furtado de Mendonca, J. P. R.; Slesinger, P.; Costa, K.; Zou, H.; Friedel, R. H.

10.1101/2024.01.02.573660 — cancer biology — Posted on 2024-01-02

4370 Hybrid cancer stem cells utilise vascular tracks for collective streaming invasion in a metastasis-on-a-chip device

Scemama, A.; Lunetto, S.; Tailor, A.; Di Cio, S.; Ambler, L.; Coetzee, A.; Cottom, H.; Khurram, S. A.; Gautrot, J.; Biddle, A.

10.1101/2024.01.02.573897 — cancer biology — Posted on 2024-01-02

4371 MatchMaps: Non-isomorphous difference maps for X-ray crystallography

Brookner, D. E.; Hekstra, D. R.

10.1101/2023.09.01.555333 — biophysics — Posted on 2024-01-02

4372 Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER

Sneddon, A.; Ravindran, A.; Shanmuganandam, S.; Kanchi, M.; Hein, N.; Jiang, S.; Shirokikh, N. E.; Eyras, E.

10.1101/2022.11.29.518281 — bioinformatics — Posted on 2024-01-02

4373 OM2Seq: Learning retrieval embeddings for optical genome mapping

Nogin, Y.; Sapir, D.; Detinis Zur, T.; Weinberger, N.; Belinkov, Y.; Ebenstein, Y.; Shechtman, Y.

10.1101/2023.11.20.567868 — bioinformatics — Posted on 2024-01-02

4374 Phase diversity-based wavefront sensing for fluorescence microscopy

Johnson, C.; Guo, M.; Schneider, M. C.; Su, Y.; Khuon, S. C.; Reiser, N.; Wu, Y.; La Riviere, P. J.; Shroff, H.

10.1101/2023.12.19.572369 — bioengineering — Posted on 2024-01-02

4375 Offspring size resolves a latitudinal population growth rate paradox in rays and skates

Barrowclift, E.; Bigman, J. S.; Digel, E. D.; Berggren, P.; Dulvy, N. K.

10.1101/2024.01.02.573919 — ecology — Posted on 2024-01-02

4376 STING Licensing of Type I Dendritic Cells Potentiates Antitumor Immunity

Wang, J.; Li, S.; Wang, M.; Wang, X.; Chen, S.; Sun, Z.; Ren, X.; Huang, G.; Sumer, B. D.; Yan, N.; Fu, Y.-x.; Gao, J.

10.1101/2024.01.02.573934 — immunology — Posted on 2024-01-02

4377 Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

Elliott, B.; Marquez-Nogueraz, K. M.; Thuo, P.; DiNello, E.; Knutila, R. M.; Fritzmann, G. E.; Willis, M.; Chapman, A. B.; Cao, Q.; Barefield, D. Y.; Kuo, I. Y.

10.1101/2024.01.02.573922 — physiology — Posted on 2024-01-02

4378 Patient-Derived Tumor Organoid and Fibroblast Assembloid Models for interrogation of the tumor microenvironment in Esophageal Adenocarcinoma

Sharpe, B. P.; Nazlamova, L. A.; Tse, C.; Johnston, D. A.; Blyth, R.; Pickering, O. J.; Grace, B.; Harrington, J.; Rajak, R.; Rose-Zerilli, M.; Walters, Z. S.; Underwood, T. J.

10.1101/2024.01.02.572565 — cancer biology — Posted on 2024-01-02

4379 Genomics 2 Proteins portal: A resource and discovery tool for linking genetic screening outputs to protein sequences and structures

Kwon, S.; Safer, J.; Nguyen, D. T.; Hoksza, D.; May, P.; Arbesfeld, J.; Rubin, A. F.; Campbell, A. J.; Burgin, A.; Iqbal, S.

10.1101/2024.01.02.573913 — bioinformatics — Posted on 2024-01-02

4380 De Novo Atomic Protein Structure Modeling for Cryo-EMDensity Maps Using 3D Transformer and Hidden MarkovModel

Giri, N.; Cheng, J.

10.1101/2024.01.02.573943 — bioinformatics — Posted on 2024-01-02

4381 Beyond benchmarking: towards predictive models of dataset-specific single-cell RNA-seq pipeline performance

Fang, C.; Selega, A.; Campbell, K. R.

10.1101/2024.01.02.572650 — bioinformatics — Posted on 2024-01-02

4382 Blinking as a measurement of group vigilance in red deer Cervus elaphus and fallow deer Dama dama

Howard, T. R.; Rands, S. A.

10.1101/2024.01.02.573958 — animal behavior and cognition — Posted on 2024-01-02

4383 Fluidic shear stress alters clathrin dynamics and vesicle formation in endothelial cells

Nawara, T. J.; Sztul, E.; Mattheyses, A. L.

10.1101/2024.01.02.572628 — cell biology — Posted on 2024-01-02

4384 Identification of a chromatin-bound ERRα interactome network in mouse liver

Scholtes, C.; Dufour, C. R.; Pleynet, E.; Kamyabiazar, S.; Hutton, P.; Baby, R.; Guluzian, C.; Giguere, V.

10.1101/2024.01.02.573907 — cell biology — Posted on 2024-01-02

4385 Long range projections of oxytocin neurons in the marmoset brain

Lefevre, A.; Meza, J.; Miller, C.

10.1101/2024.01.02.573953 — neuroscience — Posted on 2024-01-02

4386 Effects of the overall paradigm context on intensity deviant responses in healthy subjects

Yukhnovich, E. A.; Alter, K.; Sedley, W.

10.1101/2024.01.02.573901 — neuroscience — Posted on 2024-01-02

4387 Musicians' brains at rest: Multilayer network analysis of MEG data

Mandke, K.; Tewarie, P.; Adjamian, P.; Schuermann, M.; Meier, J.

10.1101/2024.01.02.573886 — neuroscience — Posted on 2024-01-02

4388 The genome of Lolium multiflorum reveals the genetic architecture of paraquat resistance

Brunharo, C. A.; Short, A. W.; Bobadilla, L. K.; Streisfeld, M. A.

10.1101/2024.01.02.573904 — plant biology — Posted on 2024-01-02

4389 Cognitive and molecular characterization of the Ts66Yah murine model of Down syndrome: deepening on hippocampal changes associated with genotype and aging.

Lanzillotta, C.; Rataj-Baniowska, M.; Prestia, F.; Sette, C.; Nalesso, V.; Perluigi, M.; Barone, E.; Duchon, A.; Tramutola, A.; Herault, Y.; Di Domenico, F.

10.1101/2024.01.02.573811 — pathology — Posted on 2024-01-02

4390 Mechanisms of Cholesterol Binding to LAT1

Hutchinson, K.; Schlessinger, A.

10.1101/2024.01.02.573920 — biophysics — Posted on 2024-01-02

4391 FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA

Liu, Y.; Reed, S. C.; Lo, C.; Choudhury, A. D.; Parsons, H. A.; Stover, D. G.; Ha, G.; Gydush, G.; Rhoades, J.; Rotem, D.; Freeman, S.; Katz, D.; Bandaru, R.; Zheng, H.; Fu, H.; Adalsteinsson, V. A.; Kellis, M.

10.1101/2024.01.02.573710 — bioinformatics — Posted on 2024-01-02

4392 Architecture and infection-sensing mechanism of the bacterial PARIS defense system

Deep, A.; Liang, Q.; Enustun, E.; Pogliano, J.; Corbett, K. D.

10.1101/2024.01.02.573835 — biochemistry — Posted on 2024-01-02

4393 Dominant negative mutations in yeast Hsp90 reveal triage decision mechanism targeting client proteins for degradation

Flynn, J. M.; Joyce, M. E.; Bolon, D. N.

10.1101/2024.01.02.573950 — biochemistry — Posted on 2024-01-02

4394 Direct interrogation of context-dependent GPCR activity with a universal biosensor platform

Janicot, R.; Maziarz, M.; Park, J.-C.; Luebbers, A.; Green, E.; Zhao, J.; Philibert, C. E.; Zhang, H.; Layne, M. D.; Wu, J. C.; Garcia-Marcos, M.

10.1101/2024.01.02.573921 — biochemistry — Posted on 2024-01-02

4395 Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection

10.1101/2024.01.02.573894 — biochemistry — Posted on 2024-01-02

4396 White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells

Yeung, S. H.-S.; Lee, R. H.-S.; Cheng, G. W.-Y.; Ma, I. W.-T.; Kofler, J.; Kent, C.; Ma, F.; Herrup, K.; Fornage, M.; Arai, K.; Tse, K.-H.

10.1101/2023.12.18.566359 — cell biology — Posted on 2024-01-02

4397 Characterization of a novel temperate phage facilitating in vitro dispersal of multicellular bacteria

Jaffal, H.; Korbeti, M.; Misson, P.; Tavares, P.; Ouldali, M.; Leh, H.; Lautru, S.; Lioy, V. S.; Lecointe, F.; Bury-Mone, S. G.

10.1101/2023.07.22.549817 — microbiology — Posted on 2024-01-02

4398 DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection

Messmer, M.; Pierson, L.; Pasquier, C.; Djordjevic, N.; Chicher, J.; Hammann, P.; Pfeffer, S.; Girardi, E.

10.1101/2023.09.21.558232 — microbiology — Posted on 2024-01-02

4399 A Logic-incorporated Gene Regulatory Network Deciphers Principles in Cell Fate Decisions

Xue, G.; Zhang, X.; Li, W.; Zhang, L.; Zhang, Z.; Zhou, X.; Zhang, D.; Zhang, L.; Li, Z.

10.1101/2023.04.21.537440 — systems biology — Posted on 2024-01-02

4400 Virulence patterns of oat crown rust in Australia - season 2022

Henningsen, E. C.; Lewis, D. C.; Nguyen, D. T.; Sperschneider, J.; Kianian, S. F.; Stone, E.; Dodds, P.; Figueroa, M.

10.1101/2023.09.24.558528 — plant biology — Posted on 2024-01-02

4401 Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib

Pang, Y.; Li, Q.; Sergi, Z.; Yu, G.; Sang, X.; Kim, O.; Wang, H.; Ranjan, A.; Merchant, M.; Oudit, B.; Robey, R. W.; Soheilian, F.; Tran, B.; Nunez, F. J.; Zhang, M.; Song, H.; Zhang, W.; Davis, D.; Gilbert, M. R.; Gottesman, M. M.; Liu, Z.; Khan, J.; Thomas, C. J.; Castro, M. G.; Gujral, T. S.; Wu, J.

10.1101/2023.06.29.547143 — cancer biology — Posted on 2024-01-02

4402 Imputation of 3D genome structure by genetic-epigenetic interaction modeling in mice

Kuffler, L.; Fortin, H. J.; Skelly, D. A.; Czechanski, A.; Munger, S. C.; Reinholdt, L. G.; Baker, C. L.; Carter, G. W.

10.1101/2022.02.07.479436 — genetics — Posted on 2024-01-02

4403 Deciphering the molecular mechanisms underlying anti-pathogenic potential of a polyherbal formulation Enteropan against multi-drug resistant Pseudomonas aeruginosa

Parmar, S.; Gajera, G.; Thakkar, N.; Palep, H.; Kothari, V.

10.1101/2024.01.02.573864 — microbiology — Posted on 2024-01-02

4404 Beyond Antibiotics: Cinnamic Acid's role in combatting complex biofilms in the oral cavity

Al_Darwish, L.; Alajlani, M.; Alashkar, S.

10.1101/2024.01.02.573850 — microbiology — Posted on 2024-01-02

4405 Mucin-degrading gut bacteria promote anti-parasitic immunity

Wolter, M.; Boudaud, M.; Grant, E.; Parrish, A.; De Sciscio, A.; Thompson, S.; Gerardy, J.-J.; Mittelbronn, M.; Thornton, D. J.; Macpherson, A. J.; Grencis, R. K.; Desai, M. S.

10.1101/2022.02.28.482289 — immunology — Posted on 2024-01-02

4406 Rapid nongenomic estrogen signaling controls alcohol drinking behavior

Zallar, L. J.; Rivera-Irizarry, J. K.; Hamor, P. U.; Pigulevskiy, I.; Liu, D.; Welday, J. P.; Rico Rozo, A.-S.; Bender, R.; Asfouri, J.; Skelly, M. J.; Fecteau, K. M.; Hadley, C. K.; Levine, O. B.; Mehanna, H.; Nelson, S.; Miller, J.; Ghazal, P.; Bellotti, P.; Erikson, D. W.; Geri, J.; Pleil, K. E.

10.1101/2023.11.02.565358 — neuroscience — Posted on 2024-01-02

4407 No sex differences in oxygen uptake or extraction kinetics in the moderate or heavy exercise intensity domains

Solleiro Pons, M.; Bernert, L.; Hume, E.; Hughes, L.; Williams, Z.; Burnley, M.; Ansdell, P.

10.1101/2023.06.26.546455 — physiology — Posted on 2024-01-02

4408 Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers

Siri, M.; Vazquez-Davila, M.; Bidan, C. M.

10.1101/2023.09.07.556686 — biophysics — Posted on 2024-01-02

4409 ExoJ: an ImageJ2/Fiji plugin for automated spatiotemporal detection and analysis of exocytosis

Liu, J.; Verweij, F. J.; Van Niel, G.; GALLI, T.; Danglot, L.; Bun, P.

10.1101/2022.09.05.506585 — bioinformatics — Posted on 2024-01-02

4410 Sex-Specific DNA-Replication In The Early Mammalian Embryo

Halliwell, J. A.; Martin-Gonzalez, J.; Hashim, A.; Dahl, J. A.; Hoffmann, E. R.; Lerdrup, M.

10.1101/2023.12.22.572993 — genomics — Posted on 2024-01-02

4411 AI-assisted selection of mating pairs through simulation-based optimized progeny allocation strategies in plant breeding

Hamazaki, K.; Iwata, H.

10.1101/2023.01.25.525616 — genomics — Posted on 2024-01-02

4412 Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

Sim, H.; Park, H. J.; Park, G.-H.; Kim, Y. J.; Park, W.-Y.; Lee, S.-H.; Choi, M.

10.1101/2024.01.02.573827 — genomics — Posted on 2024-01-02

4413 Genetic basis of Arabidopsis thaliana responses to infection by naive and adapted isolates of turnip mosaic virus

Butkovic, A.; Ellis, T. J.; Gonzalez, R.; Jaegle, B.; Nordborg, M.; Elena, S. F.

10.1101/2022.08.02.502433 — genetics — Posted on 2024-01-02

4414 A Comprehensive Allele Specific Expression Resource for the Equine Transcriptome

Heath, H. D.; Peng, S.; Szmatola, T.; Bellone, R. R.; Kalbfleish, T.; Petersen, J. L.; Finno, C. J.

10.1101/2023.12.31.573798 — genetics — Posted on 2024-01-02

4415 Ecological diversification in an adaptive radiation of plants: the role of de novo mutation and introgression

Stone, B. W.; Wessinger, C. A.

10.1101/2023.11.01.565185 — evolutionary biology — Posted on 2024-01-02

4416 The role of transposon activity in shaping cis-regulatory element evolution after whole genome duplication

Monsen, O.; Gronvold, L.; Datsomor, A.; Harvey, T. N.; Kijas, J.; Suh, A. S.-J.; Hvidsten, T. R.; Sandve, S. R.

10.1101/2024.01.02.573861 — evolutionary biology — Posted on 2024-01-02

4417 Effects of joint invasion: how co-invaders affect each other's success in model food webs?

Moreh, A.; Jordan, F.; Scheuring, I.

10.1101/2024.01.02.573872 — ecology — Posted on 2024-01-02

4418 Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice.

Sun, L.; Lv, Z.; Chen, X.; Ye, R.; Tian, S.; Wang, C.; Xie, X.; Yan, L.; Yao, X.; Shao, Y.; Cui, S.; Chen, J.; Liu, J.

10.1101/2023.06.21.545885 — developmental biology — Posted on 2024-01-02

4419 Evolution and favored change: a principle of least selection

Yarus, M.

10.1101/2021.06.27.450095 — molecular biology — Posted on 2024-01-02

4420 Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity

Karsten, C. B.; Buttner, F. F. R.; Cajic, S.; Nehlmeier, I.; Roshani, B.; Klippert, A.; Sauermann, U.; Stolte-Leeb, N.; Reichl, U.; Gerardy-Schahn, R.; Rapp, E.; Stahl-Hennig, C.; Pohlmann, S.

10.1101/2024.01.02.572735 — microbiology — Posted on 2024-01-02

4421 An Arm-to-Disarm Strategy to Overcome Phenotypic AMR in Mycobacterium tuberculosis

Kumar, T. A.; Birua, S.; M, S. C.; Mukherjee, P.; Singh, S.; Kaul, G.; Akhir, A.; Chopra, S.; Hirschi, J.; Singh, A.; Chakrapani, H.

10.1101/2023.03.23.533925 — microbiology — Posted on 2024-01-02

4422 Metatranscriptomic analysis indicates prebiotic effect of Isomalto/malto-polysaccharides on human colonic microbiota in-vitro

Borewicz, K.; Hornung, B. V. H.; Gu, F.; van der Zaal, P. H.; Schols, H. A.; Schaap, P. J.; Smidt, H.

10.1101/2023.12.31.573771 — microbiology — Posted on 2024-01-02

4423 Beyond Blast: Enabling Microbiologists to Better Extract Literature, Taxonomic Distributions and Gene Neighborhood Information for Protein Families

Reed, C. J.; Denise, R.; Hourihan, J.; Babor, J.; Jaroch, M.; Martinelli, M.; Hutinet, G.; de Crecy-Lagard, V.

10.1101/2023.05.03.539116 — microbiology — Posted on 2024-01-02

4424 Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

Liu, C. S. C.; Mandal, T.; Biswas, P.; Hoque, M. A.; Bandopadhyay, P.; Sinha, B. P.; Sarif, J.; D'Rozario, R.; Sinha, D. K.; Sinha, B.; Ganguly, D.

10.1101/2022.08.16.504114 — immunology — Posted on 2024-01-02

4425 Impaired microglial phagocytosis promotes seizure development

Bosco, D. B.; Kremen, V.; Haruwaka, K.; Zhao, S.; Wang, L.; Ebner, B. A.; Zheng, J.; Perry, J.; Xie, M.; Nguyen, A. T.; Worrell, G. A.; Wu, L.-J.

10.1101/2023.12.31.573794 — neuroscience — Posted on 2024-01-02

4426 Sensory experience steers representational drift in mouse visual cortex

Bauer, J.; Lewin, U.; Herbert, E.; Gjorgjieva, J.; Schoonover, C. E.; Fink, A. J. P.; Rose, T.; Bonhoeffer, T.; Hübener, M.

10.1101/2023.09.22.558966 — neuroscience — Posted on 2024-01-02

4427 Cholinergic input to mouse visual cortex signals a movement state and acutely enhances layer 5 responsiveness

Yogesh, B.; Keller, G. B.

10.1101/2023.06.07.543871 — neuroscience — Posted on 2024-01-02

4428 Unraveling variant-to-function relationships by integrating SNP-specific gene expression networks and metabolic models

Sasikumar, S.; S, P. K.; Bhatt, N.; Sinha, H.

10.1101/2023.09.13.557398 — systems biology — Posted on 2024-01-02

4429 Exploring Quorum-Sensing-Based Bacterial GMOs for Addressing Bovine Mastitis: A Developmental Approach.

Adhikary, A.; Dutta, A.; Ghosh, U.; Chatterjee, S.; Borkar, S.; Das, S.

10.1101/2023.08.07.552207 — synthetic biology — Posted on 2024-01-02

4430 Metabolome and transcriptome profiling of root chicory provide insights into laticifer development and specialized metabolism

Vahabi, K.; Balcke, G. U.; Hakkert, J. C.; van der Meer, I.; Athmer, B.; Tissier, A. F.

10.1101/2024.01.02.573856 — plant biology — Posted on 2024-01-02

4431 Kinex infers causal kinases from phosphoproteomics data

Valeanu, A.; Golz, V.; Avila, D. W.; Tzouros, M.; Siebourg-Polster, J.; Badi, L.; Zhang, J. D.

10.1101/2023.11.23.568445 — pharmacology and toxicology — Posted on 2024-01-02

4432 Integrated Analyses of Multi-omic Data Derived from Paired Primary Lung Cancer and Brain Metastasis Reveals the Metabolic Vulnerability as a Novel Therapeutic Target

Duan, H.; Ren, J.; Wei, S.; Li, C.; Wang, Z.; Li, M.; Wei, Z.; Yang, Z.; Liu, Y.; Xie, Y.; Wu, S.; Hu, W.; Guo, C.; Zhang, X.; Liang, L.; Yu, C.; Mou, Y.; Jiang, Y.; Li, H.; Sugarman, E.; Deek, R. A.; Chen, Z.; Chen, L.; Chen, Y.; Yao, M.; Liu, L.; Zhang, G.; Mou, Y.

10.1101/2024.01.02.573855 — cancer biology — Posted on 2024-01-02

4433 Brd4-Nutm1 fusion gene initiates NUT carcinoma in vivo

Zheng, D.; El Negiry, A.; Luo, C.; Bendahou, M. A.; Xie, L.; Bell, D.; Takahashi, Y.; Hanna, E.; Mias, G. I.; Tsoi, M. F.; Gu, B.

10.1101/2023.07.29.551125 — cancer biology — Posted on 2024-01-02

4434 Optical Genome Mapping for detecting Homologous Recombination Deficiency (HRD) in human breast and ovarian cancers

Vanhuele, S.; Kirova, Y.; Hamy-Petit, A.-S.; Rapinat, A.; Gentien, D.; Callens, C.; Villy, M.-C.; Reyal, F.; Vincent-Salomon, A.; Eeckhoutte, A.; Rodrigues, M.; Stern, M.-H.; Popova, T.

10.1101/2022.12.23.521790 — cancer biology — Posted on 2024-01-02

4435 Molecular Dynamics Simulation as a Promising Approach for Computational Study of Liquid Crystal-based Aptasensors

Zahraee, H.; Arab, S. S.; Khoshbin, Z.; Taghdisi, S. M.; Abnous, K.

10.1101/2022.11.19.517204 — biophysics — Posted on 2024-01-02

4436 MntJULiP and Jutils: Differential splicing analysis of RNA-seq data with covariates

Lui, W. W.; Yang, G.; Florea, L.

10.1101/2024.01.01.573825 — bioinformatics — Posted on 2024-01-02

4437 HortGenome Search Engine, a universal genomic search engine for horticultural crops

Wang, S.; Wei, S.; Deng, Y.; Wu, S.; Peng, H.; Qing, Y.; Zhai, X.; Zhou, S.; Li, J.; Li, H.; Feng, Y.; Yi, Y.; Li, R.; Zhang, H.; Wang, Y.; Zhang, R.; Ning, L.; Yao, Y.; Fei, Z.; Zheng, Y.

10.1101/2024.01.01.573844 — bioinformatics — Posted on 2024-01-02

4438 ThermoFinder: A sequence-based thermophilic proteins prediction framework

Yu, H.; Luo, X.

10.1101/2024.01.02.573852 — bioinformatics — Posted on 2024-01-02

4439 Biological insights from plasma proteomics of non-small cell lung cancer patients treated with immunotherapy

Bar, J.; Leibowitz, R.; Reinmuth, N.; Ammendola, A.; Jacob, E.; Moskovitz, M.; Levy-Barda, A.; Lotem, M.; Katzenelson, R.; Agbarya, A.; Abu-Amna, M.; Gottfried, M.; Harkovsky, T.; Wolf, I.; Tepper, E.; Loewenthal, G.; Yellin, B.; Brody, Y.; Dahan, N.; Yanko, M.; Lahav, C.; Harel, M.; Raveh-Shoval, S.; elon, y.; Sela, I.; Dicker, A. P.; Shaked, Y.

10.1101/2024.01.02.573876 — bioinformatics — Posted on 2024-01-02

4440 ExploreTurns: A web tool for the exploration, analysis and retrieval of beta turns and their contexts; application to beta-bulge loops and helix capping

Newell, N. E.

10.1101/2024.01.01.573820 — bioinformatics — Posted on 2024-01-02

4441 Predicting functionally important breast cancer SNPs using pleiotropy, conservation, and protein structure

Cheng, A. C.; Carpenter, M. A.

10.1101/2024.01.01.573831 — bioinformatics — Posted on 2024-01-02

4442 Self-Supervised Electrocardiograph De-noising

Liu, X.

10.1101/2024.01.01.573833 — bioengineering — Posted on 2024-01-02

4443 Polaris Neurosense: A General-Purpose Non-invasive Neurotechnology Research Platform

Schalk, G.; Shao, S.; Xiao, K.; Li, J.; Xie, J.; Guan, Y.; Wu, Z.; Chen, L.; Zhong, X.; Xu, C.; Li, G.; Yu, H.

10.1101/2024.01.01.573494 — bioengineering — Posted on 2024-01-02

4444 High-resolution low-cost LCD 3D printing of microfluidics

Shafique, H.; Karamzadeh, V.; Kim, G.; Morocz, Y.; Sohrabi-Kashani, A.; Shen, M. L.; Juncker, D.

10.1101/2023.12.31.573772 — bioengineering — Posted on 2024-01-02

4445 Plaat1l1 controls feeding induced NAPE biosynthesis and contributes to energy balance regulation in zebrafish.

Mashhadi, Z.; Yin, L.; Dosoky, N. S.; Chen, W.; Davies, S. S.

10.1101/2023.12.31.573561 — biochemistry — Posted on 2024-01-02

4446 First evidence of a causal link between genetic variation and thermal adaptation in a schistosome host snail

Maes, T.; Verheyen, J.; Senghor, B.; Mudavanhu, A.; Schols, R.; Hellemans, B.; Geslain, E.; Volckaert, F. A. M.; Gante, H. F.; Huyse, T.

10.1101/2024.01.02.573866 — ecology — Posted on 2024-01-02

4447 ABCA7-dependent Neuropeptide-Y signalling is a resilience mechanism required for synaptic integrity in Alzheimer's disease

Tayran, H.; Yilmaz, E.; Bhattarai, P.; Min, Y.; Wang, X.; Ma, Y.; Nelson, N.; Kassara, N.; Cosacak, M. I.; Dogru, R. M.; Reyes-Dumeyer, D.; Reddy, J.; Qiao, M.; Flaherty, D.; Teich, A. F.; Gunasekaran, T. I.; Yang, Z.; Tosto, G.; Vardarajan, B. N.; Is, O.; Ertekin-Taner, N.; Mayeux, R.; Kizil, C.

10.1101/2024.01.02.573893 — neuroscience — Posted on 2024-01-02

4448 BCI Toolbox: An Open-Source Python Package for the Bayesian Causal Inference Model

Zhu, H.; Beierholm, U.; Shams, L.

10.1101/2024.01.02.573851 — neuroscience — Posted on 2024-01-02

4449 Image-Based Recognition of Parasitoid Wasps Using Advanced Neural Networks

Shirali, H.; Hübner, J.; Both, R.; Raupach, M.; Schmidt, S.; Pylatiuk, C.

10.1101/2024.01.01.573817 — zoology — Posted on 2024-01-02

4450 Alzheimer's disease copathology in dementia with Lewy bodies is associated with astroglial α-synucleinopathy

Geut, H.; van den Berg, E.; Boon, B. D.; Hoozemans, J. J.; Tunold, J.-A.; Pihlstrom, L.; Jonkman, L. E.; Rozemuller, A. J.; Lemstra, E. A.; van de Berg, W. D. J.

10.1101/2024.01.02.573857 — pathology — Posted on 2024-01-02

4451 De novo multi-mechanism antimicrobial peptide design via multimodal deep learning

Wang, Y.; Gong, H.; Li, X.; Li, L.; Zhao, Y.; Bao, P.; Kong, Q.; Wan, B.; Zhang, Y.; Zhang, J.; Ni, J.; Han, Z.; Nan, X.; Ju, K.; Sun, L.; Chang, H.; Zheng, M.; Yu, Y.; Yang, X.; Zuo, X.; Li, Y.

10.1101/2024.01.02.573846 — bioengineering — Posted on 2024-01-02

4452 Downstream-of-gene (DoG) transcripts contribute to an imbalance in the cancer cell transcriptome

Avila-Lopez, P.; Xu, J.; Muhammad, N.; Yang, G.-Y.; Lauberth, S. M.

10.1101/2024.01.01.573830 — genomics — Posted on 2024-01-02

4453 G-quadruplexes as pivotal components of cis-regulatory elements in the human genome

Zhang, R.; Wang, Y.; Wang, C.; Sun, X.; Mergny, J.-L.

10.1101/2024.01.02.573847 — genomics — Posted on 2024-01-02

4454 Evolutionary impact of in vitro adaptation on virulence in the pathogen Zymoseptoria tritici

Jallet, A.; Robert-Siegwald, G.; Genissel, A.

10.1101/2023.12.31.573786 — evolutionary biology — Posted on 2024-01-02

4455 CDR Proteins of C. elegans and Related Species: Relationship to Metaxin and FAXC Proteins

Adolph, K. W.

10.1101/2024.01.02.573863 — evolutionary biology — Posted on 2024-01-02

4456 Evolution of genetic (co)variances during the worldwide invasion of Drosophila suzukii

Fraimout, A.; Chantepie, S.; Navarro, N.; Teplitsky, C.; Debat, V.

10.1101/2024.01.02.573869 — evolutionary biology — Posted on 2024-01-02

4457 Ancestral Sequence Reconstruction as a tool to detect and study de novo gene emergence

Vakirlis, N.; Acar, O.; Cherupally, V. K.; Carvunis, A.-R.

10.1101/2024.01.02.573862 — evolutionary biology — Posted on 2024-01-02

4458 Regional and fine-scale local adaptation in salinity tolerance in Daphnia inhabiting contrasting clusters of inland saline waters

Brans, K. I.; Vad, C. F.; Horvath, Z.; Santy, L.; Cuypers, K.; Ptacnik, R.; De Meester, L.

10.1101/2023.08.11.552416 — evolutionary biology — Posted on 2024-01-02

4459 Transoceanic pathogen circulation in the age of sail and steam

Blackmore, E. N.; Lloyd-Smith, J. O.

10.1101/2024.01.01.573813 — ecology — Posted on 2024-01-02

4460 Imaging spectroscopy reveals topographic variability effects on grassland functional traits and drought responses

Dao, P. D.; He, Y.; Lu, B.; Axiotis, A.

10.1101/2023.12.31.573803 — ecology — Posted on 2024-01-02

4461 Metacommunity research can benefit from including context-dependency

Kolasa, J.; Hammond, M. P.; Yan, J.

10.1101/2021.09.26.461405 — ecology — Posted on 2024-01-02

4462 A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics.

Petrova, K.; Kotov, A.; Tretiakov, M.; Monsoro-Burq, A. H.; Peshkin, L.

10.1101/2024.01.02.573882 — developmental biology — Posted on 2024-01-02

4463 Direct quantification of unicellular algae sinking velocities reveals cell size, light, and nutrient-dependence

Miettinen, T. P.; Gomez, A. L.; Wu, Y.; Wu, W.; Usherwood, T. R.; Hwang, Y.; Roller, B. R. K.; Polz, M. F.; Manalis, S. R.

10.1101/2023.06.20.545838 — cell biology — Posted on 2024-01-02

4464 Structural Basis of Conformational Dynamics in the PROTAC-Induced Protein Degradation

Zhao, H.

10.1101/2024.01.02.572291 — molecular biology — Posted on 2024-01-02

4465 Orally delivered biodegradable targeted inflammation resolving pectin-coated nanoparticles induce anastomotic healing post intestinal surgery

Lee, J. H.; Reischl, S.; Walter, R. L.; Vieregge, V.; Weber, M.-C.; Xu, R.; Chen, H.; Kasajima, A.; Friess, H.; Neumann, P.-A.; Kamaly, N.

10.1101/2024.01.01.569918 — immunology — Posted on 2024-01-02

4466 Translating phenotypic prediction models from big to small anatomical MRI data using meta-matching

Wulan, N.; An, L.; Zhang, C.; Kong, R.; Chen, P.; Bzdok, D.; Eickhoff, S. B.; Holmes, A. J.; Yeo, B. T. T.

10.1101/2023.12.31.573801 — neuroscience — Posted on 2024-01-02

4467 Histone acetyltransferase HAF2 associates with PDC to control H3K14ac and H3K23ac in ethylene response

Chen, C.-Y.; Shao, Z.; Wang, G.; Zhao, B.; Hardtke, H. A.; Leong, J.; Zhou, T.; Zhang, Y. J.; Qiao, H.

10.1101/2023.12.31.573642 — plant biology — Posted on 2024-01-02

4468 Advancing Aquaculture Monitoring through Self-Powered Remote Systems: Piezoelectric Energy Harvesting Approach

Mehdipour, I.

10.1101/2023.12.31.573301 — bioengineering — Posted on 2024-01-02

4469 Intraoperative Ablation Control Based on Real-time Necrosis Monitoring Feedback: Numerical Evaluation

Murakami, R.; Mori, S.; Zhang, H.

10.1101/2023.12.31.573805 — bioengineering — Posted on 2024-01-02

4470 Beige adipose tissue-derived extracellular vesicles: a potent metabolic regulator and a novel remedy for nonalcoholic fatty liver disease

Zhang, K.; Zhang, S.; Sui, B.; Jin, Y.; Zheng, C.; Kong, L.

10.1101/2024.01.01.573808 — cell biology — Posted on 2024-01-02

4471 Long-Term Monolayer Cultivation Captures Homeostatic and Regenerative Features of Human Colonic Epithelial Cells

Fujii, S.; Wang, Y.; Meng, S.; Musich, R. J.; Espenschied, S. T.; Newhall, K.; Han, Y.; Sekiguchi, S.; Matsumoto, R.; Ciorba, M. A.; Sibley, L. D.; Okamoto, R.; Stappenbeck, T. S.

10.1101/2024.01.01.573838 — cell biology — Posted on 2024-01-02

4472 GTPase-activating protein ARAP1 regulates circular dorsal ruffles as a nutrient uptake mechanism in the Hep3B hepatocellular carcinoma cell line

Sun, X.; Li, Y.; He, Y.; Cheng, L.; Wei, J.; Du, L.; Shen, Z.; Yoshida, S.

10.1101/2023.12.31.573800 — cell biology — Posted on 2024-01-02

4473 Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors

Wang, W.; Xing, J.; Zhang, X.; Liu, H.; Jiang, H.; Xu, C.; Zhao, X.; Hu, Z.

10.1101/2024.01.01.573824 — cell biology — Posted on 2024-01-02

4474 Integrative spatiotemporal map of nucleocytoplasmic transport

Raveh, B.; Eliasian, R.; Rashkovits, S.; Russel, D.; Hayama, R.; Sparks, S.; Singh, D.; Lim, R.; Villa, E.; Rout, M. P.; Cowburn, D.; Sali, A.

10.1101/2023.12.31.573409 — cell biology — Posted on 2024-01-02

4475 Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription

Zhang, Q.; Kim, W.; Panina, S.; Mayfield, J. E.; Portz, B.; Zhang, Y.

10.1101/2024.01.01.573828 — cell biology — Posted on 2024-01-02

4476 Four Years of COVID-19: Saudi Arabia, Egypt and Pakistan Have the Highest Research Growth Rates From 2020-2023

Hassan, W.; Zafar, M.

10.1101/2023.12.31.573759 — scientific communication and education — Posted on 2024-01-02

4477 Predictive coding in the auditory brainstem

de Cheveigne, A.

10.1101/2023.12.31.573202 — neuroscience — Posted on 2024-01-02

4478 A 3D Clinical Face Phenotype Space of Genetic Syndromes using a Triplet-Based Singular Geometric Autoencoder

Mahdi, S. S.; Caldeira, E.; Matthews, H.; Vanneste, M.; Nauwelaers, N.; Yuan, M.; Gong, S.; Bouritsas, G.; Baynam, G. S.; Hammond, P.; Spritz, R.; Klein, O. D.; Bronstein, M.; Hallgrimsson, B. D.; Peeters, H.; Claes, P.

10.1101/2022.12.27.521999 — bioengineering — Posted on 2024-01-02

4479 Artificial selection for microbial collective composition can succeed or fail depending on the initial and target values

Lee, J.; Shou, W.; Park, H. J.

10.1101/2023.03.07.531234 — evolutionary biology — Posted on 2024-01-02

4480 Mt or not Mt: Temporal variation in detection probability in spatial capture-recapture and occupancy models

Sollmann, R.

10.1101/2023.08.08.552394 — ecology — Posted on 2024-01-02

4481 Tim-1 and Tim-4 mediate entry of the human Kaposi's sarcoma-associated herpesvirus and the related rhesus monkey rhadinovirus

Scribano, S.; Schlagowski, S.; Liu, S.; Fricke, T.; Yang, X.; Neipel, F.; Grosskopf, A. K.; Hornich, B. F.; Backovic, M.; Ensser, A.; Hahn, A. S.

10.1101/2023.10.10.561662 — microbiology — Posted on 2024-01-02

4482 Autophagy Restricts Tomato Fruit Ripening Via a General Role in Ethylene Repression

Kumaran, G.; Pathak, P. K.; Quandoh, E.; Mursalimov, S. R.; Devi, J.; Tuvia-Alkalai, S.; Leong, J. X.; Schenstnyi, K.; Levin, E.; Üstün, S.; Michaeli, S.

10.1101/2023.12.20.572633 — plant biology — Posted on 2024-01-02

4483 STAIG: Spatial Transcriptomics Analysis via Image-Aided Graph Contrastive Learning for Domain Exploration and Alignment-Free Integration

Yang, Y.; Cui, Y.; Zeng, X.; Zhang, Y.; Loza Lopez, M. d. J.; Park, S.-J.; Nakai, K.

10.1101/2023.12.18.572279 — bioinformatics — Posted on 2024-01-02

4484 mini-MEndR: A 96-well mixed species assay to co-evaluate human and mouse Pax7+ cell-mediated skeletal muscle repair

Gulati, N.; Davoudi, S.; Xu, B.; Rjaibi, S. T.; Jacques, E.; Pham, J.; Fard, A.; McGuigan, A. P.; Gilbert, P. M.

10.1101/2023.01.20.524941 — bioengineering — Posted on 2024-01-02

4485 FAST: a fast and scalable factor analysis for spatially aware dimension reduction of multi-section spatial transcriptomics data

Liu, W.; Zhang, X.; Chai, X.; Fan, Z.; Lin, H.; Chen, J.; Sun, L.; Yu, T.; Yeong, J.; Liu, J.

10.1101/2023.07.11.548486 — genomics — Posted on 2024-01-02

4486 Association between electrophysiological phenotypes and Kv2.1 potassium channel expression explained by geometrical analysis

Reyes-Garibaldi, J. C.; Herrera-Valdez, M. A.

10.1101/2023.12.20.572720 — neuroscience — Posted on 2024-01-02

4487 Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data

Rehak Buckova, B.; Fraza, C.; Rehak, R.; Kolenic, M.; Beckmann, C.; Spaniel, F.; Marquand, A.; Hlinka, J.

10.1101/2023.06.09.544217 — neuroscience — Posted on 2024-01-02

4488 Ecological tradeoffs lead to complex evolutionary trajectories and sustained diversity on dynamic fitness landscapes

Amado, A.; Bank, C.

10.1101/2023.10.11.561986 — evolutionary biology — Posted on 2024-01-02

4489 Dihydroceramide desaturase governs endoplasmic reticulum and lipid droplet homeostasis to promote glial function in the nervous system

Zhu, Y.; Cho, K.; Lacin, H.; Zhu, Y.; DiPaola, J.; Wilson, B. A.; Patti, G. J.; Skeath, J. B.

10.1101/2024.01.01.573836 — developmental biology — Posted on 2024-01-02

4490 Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

Dong, J.; Chen, M.; van Weering, J. R. T.; Li, K. W.; Smit, A. B.; Toonen, R. F.; Verhage, M.

10.1101/2024.01.02.573873 — neuroscience — Posted on 2024-01-02

4491 Efficient DNA-based data storage using shortmer combinatorial encoding

Preuss, I.; Rosenberg, M.; Yakhini, Z.; Anavy, L.

10.1101/2021.08.01.454622 — synthetic biology — Posted on 2024-01-02

4492 Cryo2StructData: A Large Labeled Cryo-EM Density Map Dataset for AI-based Modeling of Protein Structures

Giri, N.; Wang, L.; Cheng, J.

10.1101/2023.06.14.545024 — bioinformatics — Posted on 2024-01-02

4493 Complex changes in serum protein levels in COVID-19 convalescents

Pushalkar, S.; Wu, S.; Maity, S.; Pressler, M.; Rendleman, J.; Jeffrey, L. Y.; Vitrinel, B.; Carlock, M. A.; Ross, T.; Choi, H.; Vogel, C.

10.1101/2022.10.26.513886 — immunology — Posted on 2024-01-02

4494 Prioritized neural processing of social threats during perceptual decision-making

El Zein, M.; Mennella, R.; Sequestro, M.; Meaux, E.; Wyart, V.; Grezes, J.

10.1101/859942 — neuroscience — Posted on 2024-01-02

4495 How Absence Seizures Impair Sensory Perception: Insights from Awake fMRI and Simulation Studies in Rats

Stenroos, P.; Guillemain, I.; Tesler, F.; Montigon, O.; Collomb, N.; Stupar, V.; Destexhe, A.; Coizet, V.; David, O.; Barbier, E. L.

10.1101/2023.07.26.550701 — neuroscience — Posted on 2024-01-02

4496 SORBET: Automated cell-neighborhood analysis of spatial transcriptomics or proteomics for interpretable sample classification via GNN

Shimonov, S.; Cunningham, J.; Talmon, R.; Aizenbud, L.; Desai, S.; Rimm, D.; Schalper, K.; Kluger, H.; Kluger, Y.

10.1101/2023.12.30.573739 — bioinformatics — Posted on 2024-01-02

4497 Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Raimi, O.; Ojha, H.; Ehses, K.; Dederer, V.; Lange, S.; Rivera, C. P.; Deegan, T.; Chen, Y.; Wightman, M.; Toth, R.; Labib, K.; Mathea, S.; Ranson, N.; Fernandez-Busnadiego, R.; Muqit, M.

10.1101/2023.12.23.573181 — biochemistry — Posted on 2024-01-02

4498 Enhancing Sustainable Agriculture in Sub-Saharan Africa: The Potentials of Entomopathogenic Nematodes for Pest Control

Osawe, N. E.

10.1101/2023.12.30.573611 — zoology — Posted on 2024-01-02

4499 Rapid and specific detection of single nanoparticles and viruses in microfluidic laminar flow via confocal fluorescence microscopy

Drori, P.; Mouhadeb, O.; Munoz, G. G. M.; Razvag, Y.; Alcalai, R.; Klocke, P.; Cordes, T.; Zahavy, E.; Lerner, E.

10.1101/2023.12.31.573251 — biophysics — Posted on 2024-01-02

4500 Major role of S-glycoprotein in providing immunogenicity and protective immunity in mRNA lipid nanoparticle vaccines based on SARS-CoV-2 structural proteins

Bykonia, E. N.; Kleymenov, D. A.; Gushchin, V. A.; Sinyavin, A. E.; Mazunina, E. P.; Kuznetsova, N.; Kozlova, S. R.; Zolotar, A. N.; Shidlovskaya, E. V.; Usachev, E. V.; Pochtovyi, A. A.; Kustova, D. D.; Ivanov, I. A.; Dmitriev, S. E.; Ivanov, R. A.; Logunov, D. Y.; Gintsburg, A. L.

10.1101/2023.12.30.573713 — immunology — Posted on 2024-01-02

4501 DNA origami vaccine (DoriVac) nanoparticles improve both humoral and cellular immune responses to infectious diseases

Zeng, Y.; Young, O.; Si, L.; Ku, M. W.; Isinelli, G.; Rajwar, A.; Jiang, A.; Wintersinger, C.; Graveline, A.; Vernet, A.; Sanchez, M.; Ryu, J. H.; Kwon, I. C.; Goyal, G.; Ingber, D.; Shih, W.

10.1101/2023.12.29.573647 — immunology — Posted on 2024-01-02

4502 An ATP-Binding Cassette Transporter Gene Links Innate and Adaptive Immune Responses

Wilcox, S.; Arora, H.; Choi, K. B.; Kari, S.; Munro, L.; Pfeifer, C. G.; Jefferies, W. A.

10.1101/2023.12.31.573785 — immunology — Posted on 2024-01-02

4503 Evaluation of Microplate Handling Accuracy for Applying Robotic Arms in Laboratory Automation

Harazono, Y.; Shimono, H.; Hata, K.; Mitsuyama, T.; Horinouchi, T.

10.1101/2023.12.29.573685 — systems biology — Posted on 2024-01-02

4504 Identifying Factors Important for Conservation at Sites of Synonymous Variations

Ramasubramanian, A.; Sunderam, U.; Srinivasan, R.

10.1101/2024.01.01.573819 — bioinformatics — Posted on 2024-01-02

4505 Unravelling the conundrum of nucleolar NR2F1 localization: A comparative analysis of NR2F1 antibody-based approaches in vitro and in vivo.

Bertacchi, M.; Theiss, S.; Ahmed, A.; Eibl, M.; Loubat, A.; Maharaux, G.; Phromkrasae, W.; Chakrabandhu, K.; Camgöz, A.; Schaaf, C. P.; Studer, M.; Laugsch, M.

10.1101/2023.12.31.573551 — cell biology — Posted on 2024-01-02

4506 Sensitive and error-tolerant annotation of protein-coding DNA with BATH

Krause, G.; Shands, W.; Wheeler, T.

10.1101/2023.12.31.573773 — bioinformatics — Posted on 2024-01-01

4507 Targeting the G-quadruplex structure in the hTERT promoter: In silico screening of phytocompounds and replica exchange molecular dynamics simulations.

Uttarkar, A.; Niranjan, V.

10.1101/2023.12.31.573762 — bioinformatics — Posted on 2024-01-01

4508 Image processing tools for petabyte-scale light sheet microscopy data

Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J.; Killilea, A.; Betzig, E.; Upadhyayula, S.

10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-01-01

4509 Saturated fatty acid-Coenzyme A supplementation restores neuronal energy levels and protein homeostasis in hereditary spastic paraplegia

Saber, S. H.; Yak, N.; Yong, X. L. H.; Lu, S.; Binder, T.; Purushothaman, R.; Gaudin, A.; Harmer, J.; Talbo, G.; van Waardenberg, A. J.; Anggono, V.; Balistreri, G.; Joensuu, M.

10.1101/2023.12.31.573799 — neuroscience — Posted on 2024-01-01

4510 Spindle Oscillation Emerges at the Critical State of the Electrically Coupled Network in Thalamic Reticular Nucleus

Li, S.; Wang, C.; Wu, S.

10.1101/2023.12.31.573769 — neuroscience — Posted on 2024-01-01

4511 GPT-4V exhibits human-like performance in biomedical image classification

Hou, W.; Ji, Z.

10.1101/2023.12.31.573796 — bioinformatics — Posted on 2024-01-01

4512 Conditioned overconsumption is dependent on reinforcer type in lean, but not obese, mice.

Lewis-Sanders, D.; Bullich, S.; Olvera, M. J.; Vo, J.; Hwang, Y.-S.; Stern, S. A.

10.1101/2023.12.31.573797 — animal behavior and cognition — Posted on 2024-01-01

4513 Single-Nuclei RNA Sequencing Identifies Type C Low-Threshold Mechanoreceptors as Key Players in Paclitaxel-Induced Peripheral Neuropathy

Sun, W.; Li, R.; Zhang, X.; Wu, S.; Jiang, Y.; Li, Q.; Cao, D.; Xiong, D.; Xiao, L.; Liu, X.

10.1101/2023.12.31.573703 — neuroscience — Posted on 2024-01-01

4514 The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics

McCormick, L. E.; Evans, E. B.; Barker, N. K.; Herring, L. E.; Gupton, S. L.

10.1101/2023.12.31.573790 — cell biology — Posted on 2024-01-01

4515 Constitutive Endolysosomal Perforation in Neurons allows Induction of alpha-Synuclein Aggregation by Internalized Pre-Formed Fibrils

Sanyal, A.; Scanavachi, G.; Somerville, E.; Saminathan, A.; Nair, A.; Oikonomou, A.; Hatzakis, N. S.; Kirchhausen, T.

10.1101/2023.12.30.573738 — cell biology — Posted on 2024-01-01

4516 MIWI arginines orchestrate generation of functional pachytene piRNAs and spermiogenesis

Vrettos, N.; Oppelt, J.; Zoch, A.; Sgourdou, P.; Yoshida, H.; Song, B.; Fink, R.; OCarroll, D.; Mourelatos, Z.

10.1101/2023.12.31.573779 — molecular biology — Posted on 2024-01-01

4517 Flagella are required to coordinately activate competition and host colonization factors in response to a mechanical signal

Speare, L.; Zhao, L.; Pavelsky, M. N.; Jackson, A.; Smith, S.; Tyagi, B.; Sharpe, G. C.; Woo, M.; Satkowiak, L.; Bolton, T.; Gifford, S. M.; Septer, A. N.

10.1101/2023.12.31.573711 — microbiology — Posted on 2024-01-01

4518 Basolateral amygdala population coding of a cued reward seeking state depends on orbitofrontal cortex

Ottenheimer, D. J.; Vitale, K. R.; Ambroggi, F.; Janak, P. H.; Saunders, B. T.

10.1101/2023.12.31.573789 — neuroscience — Posted on 2024-01-01

4519 Novel gramicidin-derived ????-helical antimicrobialpeptides

Lambden, E.; Ulmschneider, M. B.

10.1101/2023.12.31.573784 — biophysics — Posted on 2024-01-01

4520 Hunting for peptide binders of specific targets with data-centric generative language models

Nie, Z.; Li, D.; Chen, J.; Xu, F.; Liu, Y.; Fu, J.; Liu, X.; Wang, Z.; Ma, Y.; Wang, K.; Zhang, J.; Hu, Z.; Song, G.; Ye, Y.; Yin, F.; Zhou, B.; Liu, Z.; Li, Z.; Gao, W.; Tian, Y.

10.1101/2023.12.31.573750 — bioinformatics — Posted on 2024-01-01

4521 Specifying cellular context of transcription factor regulons for exploring context-specific gene regulation programs

Minaeva, M.; Domingo, J.; Rentzsch, P.; Lappalainen, T.

10.1101/2023.12.31.573765 — bioinformatics — Posted on 2024-01-01

4522 Activation and depression of neural and hemodynamic responses induced by the intracortical microstimulation and visual stimulation in the mouse visual cortex.

Suematsu, N.; Vazquez, A. L.; Kozai, T. D. Y.

10.1101/2024.01.01.573814 — bioengineering — Posted on 2024-01-01

4523 Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism

Shihoya, W.; Akasaka, H.; Jordan, P. A.; Lechne, A.; Okada, B. K.; Cruz, G. C. M. d.; Sano, F. K.; Tanaka, T.; Kawahara, R.; Chaudhari, R.; Masamune, H.; Mark, B. J.; Nureki, O.

10.1101/2023.12.30.573741 — biochemistry — Posted on 2024-01-01

4524 Transforming chemigenetic bimolecular fluorescence complementation systems into chemical dimerizers using chemistry

Kumar, P.; Gutu, A.; Waring, A.; Brown, T. A.; Lavis, L. D.; Tebo, A. G.

10.1101/2023.12.30.573644 — biochemistry — Posted on 2024-01-01

4525 A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells

Smith, J. J.; Valentino, T. R.; Ablicki, A. H.; Banerjee, R.; Colligan, A. R.; Eckert, D. M.; Desjardins, G. A.; Diehl, K. L.

10.1101/2023.12.31.573774 — biochemistry — Posted on 2024-01-01

4526 Chromatin structure and 3D architecture define differential functions of PU.1 cis regulatory elements in human blood cell lineages

Qiu, K.; Vu, D.; Wang, L.; Bookstaver, A.; Dinh, T. N.; Goldfarb, A. N.; Tenen, D. G.; Trinh, B. Q.

10.1101/2024.01.01.573782 — genetics — Posted on 2024-01-01

4527 DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pluripotent Stem Cell

Alsolami, S.; Chandrasekaran, A. P.; Jin, Y.; Shakir, I. M.; Zhang, Y.; Ramos-Mandujano, G.; Yuan, B.; Saera-Vila, A.; Izpisua Belm, J. C. o.; Li, M.

10.1101/2023.12.31.573770 — developmental biology — Posted on 2024-01-01

4528 Mitochondrial choline import regulates purine nucleotide pools via SLC25A48

Verkerke, A. R. P.; Shi, X.; Abe, I.; Gerszten, R. E.; Kajimura, S.

10.1101/2023.12.31.573776 — cell biology — Posted on 2024-01-01

4529 Cell therapy with human iPSC-derived cardiomyocyte aggregates leads to efficient engraftment and functional recovery after myocardial infarction in non-human primates

Gruh, I.; Martens, A.; Cebotari, S.; Schrod, A.; Haase, A.; Halloin, C.; Triebert, W.; Goecke, T.; Arar, M.; Hoeffler, K.; Frank, P.; Lampe, K.; Moussavi, A.; Fricke, V.; Kriedemann, N.; Monika, S.; Maetz-Rensing, K.; Eiringhaus, J.; de Vries, A.-L.; Barnekow, I.; Ferrel, C. S.; Hohmann, S.; Witte, M.; Kohrn, T.; Teske, J.; Lupanow, V.; Franke, A.; Kuehnel, M.; Jonigk, D.; Boretius, S.; Veltmann, V.; Duncker, D.; Hilfiker, A.; Haverich, A.; Zweigerdt, R.; Martin, U.

10.1101/2023.12.31.573775 — cell biology — Posted on 2024-01-01

4530 Transient BRD4 degradation improves cardiac reprogramming by inhibiting macrophage/Oncostatin M induced JAK/STAT pathway

Liu, L.; Guo, Y.; Tian, S.; Lei, I.; Gao, W.; Li, Z.; Wang, S.; Chen, E.; Wang, Z.

10.1101/2023.12.31.573781 — cell biology — Posted on 2024-01-01

4531 MobiChIP: a compatible library construction method of single-cell ChIP-seq based droplets

Yu, X.; Zheng, G.; Xu, L.; Chen, G.; Zhu, Y.; Li, T.; Rao, M.; Cong, R.; Zheng, W.; Pei, H.

10.1101/2023.12.31.573755 — molecular biology — Posted on 2024-01-01

4532 Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase

Tong, H.; Wang, H.; Liu, N.; Li, G.; Zhou, Y.; Wu, D.; Li, Y.; Jin, M.; Wang, X.; Li, H.; Wei, Y.; Yuan, Y.; Shi, L.; Yao, X.; Yang, H.

10.1101/2024.01.01.573809 — molecular biology — Posted on 2024-01-01

4533 Three new species in the Onygenaceae isolated from marine environment

Wang, M.-M.

10.1101/2023.12.31.573767 — microbiology — Posted on 2024-01-01

4534 A food color based colorimetric assay for Cryptococcus neoformans laccase activity

Ramirez, L. R. S.; Dragotakes, Q.; Casadevall, A.

10.1101/2024.01.01.573823 — immunology — Posted on 2024-01-01

4535 Automated liquid handling extraction and rapid quantification of underivatized amino acids and tryptophan metabolites from human serum and plasma using dual-column U(H)PLC-MRM-MS and its application to prostate cancer study.

Kipura, T.; Hotze, M.; Hofer, A.; Egger, A.-S.; Timpen, L. E.; Opitz, C.; Townsend, P.; Gethings, L.; Thedieck, K.; Kwiatkowski, M.

10.1101/2023.12.31.573763 — biochemistry — Posted on 2024-01-01

4536 Pose analysis in free-swimming adult zebrafish, Danio rerio:"fishy" origins of movement design

Kanwal, J. S.; Sanghera, B.; Dabbi, R.; Glasgow, E.

10.1101/2023.12.31.573780 — animal behavior and cognition — Posted on 2024-01-01

4537 Maternal gut Bifidobacterium breve modifies fetal brain metabolism in mice

Lopez-Tello, J.; Kiu, R.; Schofield, Z.; van Sinderen, D.; Le Gall, G.; Hall, L. J.; Sferruzzi-Perri, A.

10.1101/2023.12.31.573756 — developmental biology — Posted on 2024-01-01

4538 Human DDIT4L intron retention contributes to cognitive impairment and amyloid plaque formation.

Li, k. c.; shi, h. x.; li, z.; you, p.; pan, j.; cai, y. c.; li, j. w.; ma, x. f.; zhang, s.; diao, l.; cai, b.; lu, y.; wang, h. b.; zhong, y. q.; chen, l.; mao, y.; zhang, x.

10.1101/2023.12.30.573740 — neuroscience — Posted on 2024-01-01

4539 Cryo-EM images of phase separated lipid bilayer vesicles analyzed with a machine learning approach

Sharma, K. D.; Doktorova, M.; Waxham, N.; Heberle, F. A.

10.1101/2023.12.31.573132 — biophysics — Posted on 2024-01-01

4540 Cryo-EM structure and biochemical analysis of human chemokine receptor CCR8

Peng, Q.; Jiang, H.; Cheng, X.; Wang, N.; Zhou, S.; Zhang, Y.; Yang, T.; Chen, Y.; Zhang, W.; Lv, S.; Nan, W.; Wang, J.; Fan, G.-H.; Li, J.; Zhang, J.

10.1101/2023.12.30.573520 — biophysics — Posted on 2024-01-01

4541 Multiparameter-based photosynthetic state transitions of single phytoplankton cells

Harris, P. D.; Ben Eliezer, N.; Keren, N.; Lerner, E.

10.1101/2023.12.31.573751 — biophysics — Posted on 2024-01-01

4542 Genomic background sequences systematically outperform synthetic ones in de novo motif discovery for ChIP-seq data

Raditsa, V. V.; Tsukanov, A. V.; Bogomolov, A. G.; Levitsky, V. G.

10.1101/2023.12.30.573742 — bioinformatics — Posted on 2024-01-01

4543 Straightforward semi-quantitative MALDI-TOF MS based screening approach for selection of recombinant protein producing E. Coli

Kravtsov, I. N.; Solovyev, A. I.; Potemkina, E. A.; Kartashova, A. V.; Dmitrieva, M. A.; Danilova, K. V.; Tutykhina, I. L.; Polyakov, N. B.; Egorova, D. A.

10.1101/2023.12.31.573754 — bioengineering — Posted on 2024-01-01

4544 Detection of Antibodies Against the African Parasite Trypanosoma brucei Using Synthetic glycosylphosphatidylinositol oligosaccharide fragments

Michel, M.; Stijlemans, B.; Michel, D.; Garg, M.; Geissner, A.; Seeberger, P.; Varon Silva, D.

10.1101/2023.12.31.573764 — biochemistry — Posted on 2024-01-01

4545 DNA-PKcs Suppresses Illegitimate Chromosome Rearrangements

Wang, J.; Sadeghi, C.; Frock, R. L.

10.1101/2023.12.30.573736 — genetics — Posted on 2024-01-01

4546 Genomic Transfer via Membrane Vesicle: A Strategy of Giant Phage phiKZ for Early Infection

Antonova, D.; Nichiporenko, A.; Sobinina, M.; Vishnyakov, I. E.; Moiseenko, A.; Kurdyumova, I.; Khodorkovskii, M.; Sokolova, O. S.; Yakunina, M. V.

10.1101/2023.12.31.573766 — molecular biology — Posted on 2024-01-01

4547 Spatially Resolved Transcriptomic Signatures of Hippocampal Subregions and Arc-Expressing Ensembles in Active Place Avoidance Memory

Vingan, I. P.; Tung, V. S. K.; Phatarpekar, S.; Hernandez, A. I.; Evgrafov, O. V.; Alarcon, J. M.

10.1101/2023.12.30.573225 — neuroscience — Posted on 2024-01-01

4548 Decoding of resting-state using task-based multivariate pattern analysis supports the Incentive-Sensitization Theory in nicotine use disorder

Lor, C. S.; Steyrl, D.; Zhang, M.; Zhou, F.; Becker, B.; Herdener, M.; Quednow, B. B.; Haugg, A.; Scharnowski, F.

10.1101/2023.12.31.573585 — neuroscience — Posted on 2024-01-01

4549 Neurotransmitter Genes in the Nucleus Accumbens that Are Involved in the Development of Behavioral Pathology After Positive Fighting Experiences and Their Deprivation. A Conceptual Paradigm for Neurogenomic Data Analysis

Kudryavtseva, N. N.; Smagin, D. A.; Redina, O. E.; Kovalenko, I. L.; Galyamina, A. G.; Babenko, V. N.

10.1101/2023.12.30.573683 — neuroscience — Posted on 2024-01-01

4550 Extinction Training Suppresses Activity of Fear Memory Ensembles Across the Hippocampus and Alters Transcriptomes of Fear-Encoding Cells

Zuniga, A.; Han, J.; Miller-Crews, I.; Agee, L. A.; Hofmann, H. A.; Drew, M. R.

10.1101/2023.12.31.573787 — neuroscience — Posted on 2024-01-01

4551 Transcranial direct current stimulation alters cerebrospinal fluid-interstitial fluid exchange in mouse brain

Wang, Y.; Monai, H.

10.1101/2023.12.30.573695 — neuroscience — Posted on 2024-01-01

4552 Pharmacological inhibition of mTORC1 reduces neural death and damage volume after MCAO by modulating microglial reactivity

Villa-Gonzalez, M.; Rubio, M.; Martin-Lopez, G.; R. Mallavibarrena, P.; Valles-Saiz, L.; Vivien, D.; Wandosell Jurado, F.; Perez-Alvarez, M. J.

10.1101/2023.12.31.571469 — neuroscience — Posted on 2024-01-01

4553 Piggybacking functionalized DNA nanostructures into live cell nuclei

Roozbahani, G. M.; Colosi, P.; Oravecz, A.; Sorokina, E. M.; Pfeifer, W.; Shokri, S.; Wei, Y.; Didier, P.; DeLuca, M.; Arya, G.; Tora, L.; Lakadamyali, M.; Poirier, M. G.; Castro, C.

10.1101/2023.12.30.573746 — bioengineering — Posted on 2024-01-01

4554 Phylogenomics analyses of all species of Swordtails (Genus Xiphophorus) highlights hybridization precedes speciation

Du, K.; Lu, Y.; Garcia-Olazabal, M.; Walter, R. B.; Warren, W. C.; Dodge, T.; Schumer, M.; Park, H.; Meyer, A.; Schartl, M.

10.1101/2023.12.30.573732 — genomics — Posted on 2024-01-01

4555 Functional consequences of reductive protein evolution in a minimal eukaryotic genome

Jiang, J.; Qu, R.; Grigorescu, M.; Zhao, W.; Reinke, A. W.

10.1101/2023.12.31.573788 — evolutionary biology — Posted on 2024-01-01

4556 Genomic signatures of the evolution of loss of egg yolk in parasitoid wasps

Zhao, X.; Liu, Y.; Yang, Y.; He, C.; Chan, K. C.; Lin, H.; Fang, Q.; Ye, G.; Ye, X.

10.1101/2023.12.30.573744 — evolutionary biology — Posted on 2024-01-01

4557 Indirect effects of habitat amount mediated by habitat configuration determine bat diversity at the landscape-scale in Peninsular Malaysia

Hazard, Q. C. K.; Yoh, N.; Moore, J.; Senawi, J.; Gibson, L.; Froidevaux, J. S. P.; Palmeirim, A. F.

10.1101/2023.12.30.573737 — ecology — Posted on 2024-01-01

4558 Discovery of Waddington's developmental canals elucidates the embryogenesis stability in Caenorhabditis elegans

Wang, J.; xiao, l.; yao, z.; deng, s.; Yang, J.-R.; Wu, C.-I.; Du, Z.; He, X.

10.1101/2023.12.30.573745 — developmental biology — Posted on 2024-01-01

4559 Cell density couples tissue mechanics to control the elongation speed of the body axis

Lu, C.; Vidigueira, J. M. N.; Jie, C. C. J.; Maksymiuk, A.; Xiong, F.

10.1101/2023.12.31.573670 — developmental biology — Posted on 2024-01-01

4560 Development of a PROTAC Targeting Chk1

Chowdhury, S. R.; Chuong, P.; Mgbemena, V. E.; Statsyuk, A. V.

10.1101/2023.12.30.573733 — cell biology — Posted on 2024-01-01

4561 Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation.

Tey, P. Y.; Dufner, A.; Knobeloch, K.-P.; Pruneda, J. N.; Clague, M. J.; Urbe, S.

10.1101/2023.12.31.573735 — cell biology — Posted on 2024-01-01

4562 Beyond Basic Characterization and Omics: Immunomodulatory Roles of Platelet-Derived Extracellular Vesicles Unveiled by Functional Testing

Palviainen, M.; Puutio, J.; Ostergaard, R. H.; Eble, J. A.; Maaninka, K.; Ndika, J.; Kari, O. K.; Kamali-Moghaddam, M.; Kjaer-Sorensen, K.; Oxvig, C.; Aransay, A. M.; Falcon-Perez, J. M.; Federico, A.; Greco, D.; Laitinen, S.; Hayashi, Y.; Siljander, P. R.-M.

10.1101/2023.12.31.570750 — cell biology — Posted on 2024-01-01

4563 Nucleoid-associated proteins shape the global protein occupancy and transcriptional landscape of a clinical isolate of Vibrio cholerae

Rakibova, Y.; Dunham, D. T.; Seed, K. D.; Freddolino, L.

10.1101/2023.12.30.573743 — microbiology — Posted on 2024-01-01

4564 Precision Genome Editing Unveils a Breakthrough in Reversing Antibiotic Resistance: CRISPR/Cas9 Targeting of Multi-Drug Resistance Genes in Methicillin-Resistant Staphylococcus aureus

Ates, A.; Tastan, C.; Ermertcan, S.

10.1101/2023.12.31.573511 — microbiology — Posted on 2024-01-01

4565 The brainstem's red nucleus was evolutionarily upgraded to support goal-directed action

Krimmel, S. R.; Laumann, T. O.; Chauvin, R.; Hershey, T.; Roland, J. L.; Shimony, J. S.; Willie, J. T.; Norris, S. A.; Marek, S.; Van, A. N.; Monk, J.; Scheidter, K. M.; Whiting, F.; Ramirez-Perez, N.; Metoki, A.; Wang, A.; Kay, B. P.; Nahman-Averbuch, H.; Fair, D. A.; Lynch, C. J.; Raichle, M. E.; Gordon, E. M.; Dosenbach, N. U. F.

10.1101/2023.12.30.573730 — neuroscience — Posted on 2024-01-01

4566 Mechanisms of alcohol influence on fear conditioning: a computational model

Lonnberg, A.; Logrip, M. L.; Kuznetsov, A.

10.1101/2023.12.30.573310 — neuroscience — Posted on 2024-01-01

4567 Transcriptomic Analysis Identifies Candidate Genes for Differential Expression during Xenopus laevis Inner Ear Development

Virk, S. M.; Trujillo-Provencio, C.; Serrano, E. E.

10.1101/2023.12.29.573599 — neuroscience — Posted on 2024-01-01

4568 Synaptic connectivity and electrophysiological properties of the nucleus of the lateral olfactory tract

Penker, S.; Lawabny, N.; Dhamshy, A.; Licht, T.; Rokni, D.

10.1101/2023.12.31.573522 — neuroscience — Posted on 2024-01-01

4569 KCNQ2/3 regulates efferent mediated slow excitation of vestibular afferents in mammals

Sinha, A. K.; Lee, C.; Holt, J. C.

10.1101/2023.12.30.573731 — neuroscience — Posted on 2024-01-01

Archive, 2024-01