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Archive, 2020-12

4 Computational quantification of global effects induced by mutations and drugs in signaling networks of colorectal cancer cells.
Sommariva, S.; Caviglia, G.; Ravera, S.; Frassoni, F.; Benvenuto, F.; Tortolina, L.; Castagnino, N.; Parodi, S.; Piana, M.
10.1101/2020.12.30.424842 — cancer biology — Posted on 2020-12-31
6 Evolution of lbx spinal cord expression and function
Juarez-Morales, J. L.; Weierud, F.; England, S.; Demby, C.; Santos, N.; Mazan, S.; Lewis, K.
10.1101/2020.12.30.424885 — developmental biology — Posted on 2020-12-31
7 Sequencing of clinical samples reveals that adaptation keeps establishing during H7N9 virus infection in humans
Li, L.; Ma, J.; Li, J.; Yuan, J.; Su, W.; Jin, T.; Wang, X.; Zhang, R.; Zou, R.; Li, L.; Li, J.; Fang, S.; Yuan, J.; Yang, C.; Qi, Y.; Gao, Q.; Ji, J.; Ma, K.; Fan, G.; Pei, N.; Deng, Y.; Zhou, Y.; Lin, D.; Li, F.; Ouyang, W.; Jia, H.; Liu, X.; Jiang, H.; Yang, H.; Xu, X.; Wang, H.; Liu, Y.
10.1101/2020.12.30.424890 — microbiology — Posted on 2020-12-31
8 Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress
Shytaj, I. L.; Procopio, F. A.; Tarek, M.; Carlon-Andres, I.; Tang, H.-Y.; Goldman, A. R.; Munshi, M.; Forcato, M.; Leskov, K.; Ye, F.; Lucic, B.; Cruz, N.; Singh, A.; Bicciato, S.; Padilla-Parra, S.; Lusic, M.; Diaz, R. S.; Alvarez-Carbonell, D.; Savarino, A.
10.1101/2020.12.30.424810 — immunology — Posted on 2020-12-31
9 Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates
Saunders, K. O.; Pardi, N.; Parks, R.; Santra, S.; Mu, Z.; Sutherland, L. L.; Scearce, R.; Barr, M.; Eaton, A.; Hernandez, G.; Goodman, D.; Hogan, M. J.; Tombacz, I.; Gordon, D.; Rountree, R. W.; Wang, Y.; Lewis, M. G.; Pierson, T.; Barbosa, C.; Tam, Y.; Shen, S.; Ferrari, G.; Tomaras, G. D.; Montefiori, D. C.; Weissman, D.; Haynes, B. F.
10.1101/2020.12.30.424745 — immunology — Posted on 2020-12-31
10 Preventing cancer by long-term partial Myc suppression
Sodir, N. M.; Pellegrinet, L.; Kortlever, R. M.; Kwon, Y.-W.; Kim, S.; Garcia, D.; Perfetto, A.; Anastasiou, P.; Brown Swigart, L.; Littlewood, T. D.; Evan, G. I.
10.1101/2020.12.30.422650 — cancer biology — Posted on 2020-12-31
11 Complete mitochondrial genome sequence of Bos frontalis (Gayal) from Bangladesh
Deb, G.; Khatun, R.; Hossain, S.; Rahman, S.; Bhuiyan, M.; Mobassirin, S.; Afrin, S.; Billah, M.; Baten, A.; Sarker, N.; Bhuiyan, M.; Siddiki, A. Z.
10.1101/2020.12.31.424938 — bioinformatics — Posted on 2020-12-31
12 Chromatin Interaction Neural Network (ChINN): A machine learning-based method for predicting chromatin interactions from DNA sequences
Cao, F.; Zhang, Y.; Cai, Y.; Animesh, S.; Zhang, Y.; Akincilar, S.; Loh, Y. P.; Chng, W. J.; Tergaonkar, V.; Kwoh, C. K.; Fullwood, M.
10.1101/2020.12.30.424817 — bioinformatics — Posted on 2020-12-31
27 Restoring Glutamate receptosome dynamics at synapses rescues Autism-like deficits in Shank3-deficient mice.
Moutin, E.; Sakkaki, S.; Compan, V.; Bouquier, N.; Giona, F.; Areias, J.; Goyet, E.; Hemonnot-Girard, A.-L.; Seube, V.; Benac, N.; Chastagnier, Y.; Raynaud, F.; Audinat, E.; Groc, L.; Maurice, T.; Sala, C.; Verpelli, C.; Perroy, J.
10.1101/2020.12.30.424827 — neuroscience — Posted on 2020-12-30
29 Activity-Dependent Modulation of Synapse-Regulating Genes in Astrocytes
Farhy-Tselnicker, I.; Boisvert, M. M.; Liu, H.; Dowling, C.; Erikson, G. A.; Blanco-Suarez, E.; Farhy, C.; Shokhirev, M.; Ecker, J. R.; Allen, N. J.
10.1101/2020.12.30.424365 — neuroscience — Posted on 2020-12-30
30 Synaptic plasticity of somatosensory neurons is determined by functional coupling between NMDA receptors and BK channels
Gomez, R.; Maglio, L. E.; Gonzalez-Hernandez, A. J.; Rivero-Perez, B.; Bartolome-Martin, D.; Giraldez, T.
10.1101/2020.12.30.424719 — neuroscience — Posted on 2020-12-30
31 CRP immunodeposition and proteomic analysis in abdominal aortic aneurysm
Kim, E. N.; Yu, J.; Lim, J. S.; Jeong, H.; Kim, C. J.; Choi, J.-S.; Kim, S. R.; Ahn, H.-S.; Kim, K.; Oh, S. J.
10.1101/2020.12.30.424789 — pathology — Posted on 2020-12-30
34 Process Development and Scale-up Optimization of the SARS-CoV-2 Receptor Binding Domain-Based Vaccine Candidate, RBD219-N1C1
Lee, J.; Liu, Z.; Chen, W.-H.; Wei, J.; Kundu, R.; Adhikari, R.; Altieri Rivera, J.; Gillespie, P. M.; Strych, U.; Zhan, B.; Hotez, P. J.; Bottazzi, M. E.
10.1101/2020.12.30.424829 — immunology — Posted on 2020-12-30
36 IWS1 phosphorylation by AKT3 controls nuclear export of type I IFN mRNAs and sensitivity to oncolytic viral infection, by regulating the alternative RNA splicing of U2AF2.
Laliotis, G. I.; Kenney, A.; Chavdoula, E.; Orlacchio, A.; Kaba, A. K.; La Ferlita, A.; Anastas, V.; Tsatsanis, C.; Beane, J. D.; Sehgal, L.; Coppola, V.; Yount, J. S.; Tsichlis, P. N.
10.1101/2020.12.26.424461 — cancer biology — Posted on 2020-12-30
39 Comparative transcriptomic analysis reveals key components controlling spathe color in Anthurium andraeanum (Hort.)
Osorio-Guarin, J. A.; Gopaulchan, D.; Quackenbush, C.; Lennon, A. M.; Umaharan, P.; Cornejo, O. E.
10.1101/2020.12.29.424726 — genomics — Posted on 2020-12-30
43 Land-use and forest floor explain prokaryotic metacommunity structuring and spatial turnover in Amazonian forest-to-pasture conversion areas
Rocha, F. I.; Ribeiro, T. G.; Fontes, M. A.; Shwab, S.; Coelho, M. R. R.; Lumbreras, J. F.; da Motta, P. E. F.; Teixeira, W. G.; Cole, J. R.; Borsanelli, A. C.; Dutra, I. d. S.; Howe, A.; de Oliveira, A. P.; Jesus, E. d. C.
10.1101/2020.12.30.424814 — microbiology — Posted on 2020-12-30
48 ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation
Li, Z.; Wu, Y.; Bahreini, A.; Priedigkeit, N. M.; Ding, K.; Sartorius, C. A.; Miller, L.; Rosenzweig, M.; Wagle, N.; Richer, J. K.; Muller, W. J.; Buluwela, L.; Ali, S.; Fang, Y.; Zhu, L.; Tseng, G. C.; Gertz, J.; Atkinson, J. M.; LEE, A. V.; Oesterreich, S.
10.1101/2020.12.29.424777 — cancer biology — Posted on 2020-12-30
50 MiREDiBase: a manually curated database of validated and putative editing events in microRNAs
Marceca, G. P.; Distefano, R.; Tomasello, L.; Lagana, A.; Russo, F.; Calore, F.; Romano, G.; Bagnoli, M.; Gasparini, P.; Ferro, A.; Acunzo, M.; Ma, Q.; Croce, C. M.; Nigita, G.
10.1101/2020.09.04.283689 — bioinformatics — Posted on 2020-12-30
54 Evolution of primate protomusicality via locomotion
Schruth, D. M.; Templeton, C. N.; Holman, D. J.; Smith, E. A.
10.1101/2020.12.29.424766 — evolutionary biology — Posted on 2020-12-30
55 Spatio-Temporal Coordination Of Transcription Preinitiation Complex Assembly In Live Cells
Wu, C.; Nguyen, V. Q.; Ranjan, A.; Liu, S.; Tang, X.; Ling, Y. H.; Wisniewski, J.; Mizuguchi, G.; Li, K. Y.; Jou, V.; Zheng, Q.; Lavis, L.; Lionnet, T.
10.1101/2020.12.30.424853 — molecular biology — Posted on 2020-12-30
56 Rap1, Rif2, and the Ku complex work in concert to cap chromosome ends
Rosas Bringas, F. R.; Stinus, S.; Wanders, L.; de Zoeten, P.; Cohn, M.; Chang, M.
10.1101/2020.12.30.424824 — molecular biology — Posted on 2020-12-30
59 Development of a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment.
Balderston, N. L.; Seok, D.; Makhoul, W.; Deng, Z.-D.; Girelli, T.; Teferi, M.; Smyk, N.; Jaskir, M.; Oathes, D. J.; Sheline, Y. I.
10.1101/2020.12.06.408856 — neuroscience — Posted on 2020-12-30
62 Multiple adjoining word and face selective regions in ventral temporal cortex exhibit distinct dynamics
Boring, M. J.; Silson, E. H.; Ward, M. J.; Richardson, M.; Fiez, J. A.; Baker, C. I.; Ghuman, A. S.
10.1101/2020.12.29.424760 — neuroscience — Posted on 2020-12-30
63 scMomentum: Inference of Cell-Type-Specific Regulatory Networks and Energy Landscapes
Soto, L. M.; Bernal-Tamayo, J. P.; Lehmann, R.; Balsamy, S.; Martinez-de-Morentin, X.; Vilas-Zornoza, A.; San-Martin, P.; Prosper, F.; Gomez-Cabrero, D.; Kiani, N.; Tegner, J.
10.1101/2020.12.30.424887 — systems biology — Posted on 2020-12-30
64 Characterization of cell-cell communication in COVID-19 patients
Lin, Y.; Loo, L.; Tran, A.; Moreno, C.; Hesselson, D.; Neely, G. G.; Yang, J. Y. H.
10.1101/2020.12.30.424641 — systems biology — Posted on 2020-12-30
66 Elucidation of Japanese pepper (Zanthoxylum piperitum De Candolle) domestication using RAD-Seq
Premarathne, M. D. G. P.; Fukutome, N.; Yamasaki, K.; Hayakawa, F.; Nagano, A. J.; Mizuno, H.; Ibaragi, N.; Nagano, Y.
10.1101/2020.12.29.424752 — plant biology — Posted on 2020-12-30
67 IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.
Laliotis, G. I.; Chavdoula, E.; Paraskevopoulou, M. D.; Kaba, A. D.; La Ferlita, A.; Singh, S.; Anastas, V.; Alaimo, S.; Orlacchio, A.; Nair, K. A.; Taraslia, V.; Vlachos, I.; Capece, M.; Hatzigeorgiou, A.; Palmieri, D. I.; Tsatsanis, C.; Sehgal, L.; Carbone, D. P.; Coppola, V.; Tsichlis, P. N.
10.1101/2020.07.14.195297 — cancer biology — Posted on 2020-12-30
69 PTBP1 promotes cardiac hypertrophy anddiastolic dysfunction by modulating alternativesplicing
Marti-Gomez, C.; Larrasa-Alonso, J.; Lopez-Olaneta, M.; Villalba-Orero, M.; Garcia-Pavia, P.; Sanchez-Cabo, F.; Lara-Pezzi, E.
10.1101/2020.06.30.171983 — bioinformatics — Posted on 2020-12-30
72 Preventing post-surgical cardiac adhesions with a catechol-functionalized oxime hydrogel
Fujita, M.; Policastro, G. M.; Burdick, A.; Lam, H. T.; Ungerleider, J.; Braden, R. L.; Huang, D.; Osborn, K.; Omens, J. H.; Madani, M.; Christman, K.
10.1101/2020.12.29.424755 — bioengineering — Posted on 2020-12-30
75 Gait-level analysis of mouse open field behavior using deep learning-based pose estimation
Sheppard, K.; Gardin, J.; Sabnis, G.; Peer, A.; Darrell, M.; Deats, S.; Geuther, B.; Lutz, C. M.; Kumar, V.
10.1101/2020.12.29.424780 — animal behavior and cognition — Posted on 2020-12-30
76 Genomic islands of heterozygosity maintained across caribou populations despite inbreeding
Solmundson, K.; Bowman, J.; Wilson, P. J.; Taylor, R. S.; Horn, R.; Keobouasone, S.; Manseau, M.
10.1101/2020.12.29.424772 — genomics — Posted on 2020-12-30
78 Analysis of overlapping genetic association in type 1 and type 2 diabetes
Inshaw, J. R.; Sidore, C.; Cucca, F.; Stefana, M. I.; Crouch, D. J. M.; McCarthy, M. I.; Mahajan, A.; Todd, J. A.
10.1101/2020.06.17.156778 — genetics — Posted on 2020-12-30
82 The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
Carley, E.; Stewart, R. M.; Zieman, A.; Jalilian, I.; King, D. E.; Zubek, A.; Lin, S.; Horsley, V.; King, M. C.
10.1101/2020.05.03.075085 — cell biology — Posted on 2020-12-30
83 Screening a library of FDA-approved and bioactive compounds for antiviral activity against SARS-CoV-2
Biering, S. B.; Van Dis, E.; Wehri, E.; Yamashiro, L. H.; Nguyenla, X.; Dugast-Darzacq, C.; Graham, T. G.; Stroumza, J. R.; Golovkine, G. R.; Roberts, A. W.; Fines, D. M.; Spradlin, J. N.; Ward, C. C.; Bajaj, T.; Dovala, D.; Gahmen, U. S.; Bajaj, R.; Fox, D. M.; Ott, M.; Murthy, N.; Nomura, D.; Schaletzky, J.; Stanley, S. A.
10.1101/2020.12.30.424862 — microbiology — Posted on 2020-12-30
85 ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice
Bourgeois, J. S.; Wang, L.; Alvarez, M. I.; Everitt, J.; Awadia, S.; Wittchen, E. S.; Garcia-Mata, R.; Ko, D. C.
10.1101/2020.12.30.424811 — microbiology — Posted on 2020-12-30
87 Suicidal thoughts, behaviors, and event-related potentials: A systematic review and meta-analysis
Gallyer, A. J.; Dougherty, S. P.; Burani, K.; Albanese, B. J.; Joiner, T. E.; Hajcak, G.
10.1101/2020.04.29.069005 — neuroscience — Posted on 2020-12-30
88 A genome-scale yeast library with inducible expression of individual genes
Arita, Y.; Kim, G.; Li, Z.; Friesen, H.; Turco, G.; Wang, R. Y.; Climie, D.; Usaj, M.; Hotz, M.; Stoops, E.; Baryshnikova, A.; Boone, C.; Botstein, D.; Andrews, B. J.; McIsaac, R. S.
10.1101/2020.12.30.424776 — synthetic biology — Posted on 2020-12-30
91 SPEN is Required for Xist Upregulation during Initiation of X Chromosome Inactivation
Robert-Finestra, T.; Tan, B. F.; Mira-Bontenbal, H.; Timmers, E.; Gontan-Pardo, C.; Merzouk, S.; Giaimo, B. D.; Dossin, F.; van IJcken, W. F. J.; Martens, J. W. M.; Borggrefe, T.; Heard, E.; Gribnau, J.
10.1101/2020.12.30.424676 — developmental biology — Posted on 2020-12-30
94 HP1γ sets the biological age of the intestinal epithelium
Mata -Garrido, J.; Chang-Marchand, Y.; Cherbuy, C.; Batsche, E.; Muchardt, C.; Arbibe, L.
10.1101/2020.12.30.424798 — cell biology — Posted on 2020-12-30
96 Evidence for nutrient-dependent regulation of the COPII coat by O-GlcNAcylation
Bisnett, B. J.; Condon, B. M.; Linhart, N. A.; Lamb, C. H.; Huynh, D. T.; Bai, J.; Smith, T. J.; Hu, J.; Georgiou, G. R.; Boyce, M.
10.1101/2020.12.30.424839 — cell biology — Posted on 2020-12-30
99 MAP2 is differentially phosphorylated in schizophrenia, altering its function
Grubisha, M. J.; Sun, X.; MacDonald, M. L.; Garver, M.; Sun, Z.; Paris, K. A.; Patel, D. S.; DeGiosio, R. A.; Lewis, D. A.; Nates, N. A.; Camacho, C.; Homanics, G. E.; Ding, Y.; Sweet, R. A.
10.1101/683912 — neuroscience — Posted on 2020-12-30
101 In vitro Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19
Santoso, C. S.; Li, Z.; Rottenberg, J. T.; Liu, X.; Shen, V. X.; Fuxman Bass, J. I.
10.1101/2020.12.29.424728 — immunology — Posted on 2020-12-30
103 Ticks convert pathogenic Coxiella into endosymbionts
Brenner, A. E.; Munoz-Leal, S.; Sachan, M.; Labruna, M. B.; Raghavan, R.
10.1101/2020.12.29.424491 — microbiology — Posted on 2020-12-30
105 A molecular clock controls periodically driven cell migration in confined spaces
Lee, S. H.; Hamidzadeh, A.; Yousafzai, M. S.; Ajeti, V.; Chang, H.; Murrell, M.; Levchenko, A.
10.1101/2020.12.29.424673 — systems biology — Posted on 2020-12-30
107 Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG
Carvalho, D.; Temelso, S.; Mackay, A.; Pemberton, H.; Rogers, R.; Kessler, K.; Izquierdo, E.; Bjerke, L.; Fazal-Salom, J.; Clarke, M.; Grabovska, Y.; Burford, A.; Gene-Olaciregui, N.; Boult, J.; Molinari, V.; Fofana, M.; Proszek, P.; Potente, E.; Taylor, K.; Chandler, C.; Zebian, B.; Bhangoo, R.; Martin, A.; Dabbous, B.; Stapleton, S.; Hettige, S.; Marshall, L.; Carceller, F.; Mandeville, H.; Vaidya, S.; Al-Sarraj, S.; Bridges, L.; Johnston, R.; Cryan, J.; Farrell, M.; Crimmins, D.; Caird, J.; Pears, J.; Pericoli, G.; Miele, E.; Mastronuzzi, A.; Locatelli, F.; Carai, A.; Robinson, S.; Hubank,
10.1101/2020.12.29.424674 — cancer biology — Posted on 2020-12-30
112 Centrosome-dependent microtubule organization sets the conditions for axon formation
Meka, D. P.; Kobler, O.; Wuesthoff, S.; Schwanke, B.; Krisp, C.; Schmuelling, N.; Rueter, R.; Ruecker, T.; Schluter, H.; Fornasiero, E. F.; Calderon de Anda, F.
10.1101/2020.12.29.424696 — cell biology — Posted on 2020-12-30
116 Secondary rewards acquire enhanced incentive motivation via increasing anticipatory activity of the lateral orbitofrontal cortex
Yang, X.; Liu, X.; Zeng, Y.; Wu, R.; Zhao, W.; Xin, F.; Yao, S.; Kendrick, K. M.; Ebstein, R. P.; Becker, B.
10.1101/2020.12.29.424651 — neuroscience — Posted on 2020-12-30
118 Heartbeat and Somatosensory Perception
Al, E.; Iliopoulos, F.; Nikulin, V. V.; Villringer, A.
10.1101/2020.12.29.424693 — neuroscience — Posted on 2020-12-30
119 ZeBraInspector, a whole organism screening platform enabling volumetric analysis of zebrafish brain white matter
Lempereur, S.; Simion, M.; Machado, E.; Licata, F.; Buzer, L.; Robineau, I.; Hémon, J.; Banerjee, P.; De Crozé, N.; Léonard, M.; Affaticati, P.; Jenett, A.; Talbot, H.; Joly, J.-S.
10.1101/2020.10.26.353656 — neuroscience — Posted on 2020-12-30
120 Mechanical alterations of the hippocampus in the APP/PS1 Alzheimer's disease mouse model
Antonovaite, N.; Hulshof, L. A.; Huffels, C. F. M.; Hol, E. M.; Wadman, W. J.; Iannuzzi, D.
10.1101/2020.12.29.424668 — neuroscience — Posted on 2020-12-30
121 Allelic variants of the NLR protein Rpi-chc1 differentially recognise members of the Phytophthora infestans PexRD12/31 effector superfamily through the leucine-rich repeat domain
Monino Lopez, D.; Nijenhuis, M.; Kodde, L.; Kamoun, S.; Salehian, H.; Schenstnyi, K.; Stam, R.; Lokossou, A.; Abd'el Haliem, A.; Visser, R.; Vossen, J.
10.1101/2020.12.29.424692 — plant biology — Posted on 2020-12-30
124 USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; McKinnon, C.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-12-30
132 Establishing RNA-RNA interactions remodels lncRNA structure and promotes PRC2 activity
Balas, M. M.; Hartwick, E. W.; Barrington, C.; Roberts, J. T.; Wu, S. K.; Bettcher, R.; Griffin, A. M.; Kieft, J. S.; Johnson, A. M.
10.1101/2020.04.13.040071 — biochemistry — Posted on 2020-12-30
133 Higher-order chromatin organization defines Progesterone Receptor and PAX2 binding to regulate estradiol-primed endometrial cancer gene expression
La Greca, A.; Bellora, N.; Le Dily, F.; Jara, R.; Quilez, J.; Villanueva, J. L.; Vidal, E.; Merino, G.; Fresno, C.; Tarifa Rieschle, I.; Vallejo, G.; Vicent, G.; Fernandez, E.; Beato, M.; Saragüeta, P.
10.1101/739466 — genomics — Posted on 2020-12-30
134 Impact of nitrogen and phosphorus addition on resident soil and root mycobiomes in beech forests
Clausing, S.; Likulunga, L. E.; Janz, D.; Feng, H.; Schneider, D.; Daniel, R.; Kruger, J.; Lang, F.; Polle, A.
10.1101/2020.12.29.424645 — ecology — Posted on 2020-12-30
136 Stochastic asymmetric repartition of lytic machinery in dividing human CD8+ T cells generates heterogeneous killing behavior
Lafouresse, F.; Jugele, R.; Mueller, S.; Doineau, M.; Duplan-Eche, V.; Espinosa, E.; Puissegur, M.-P.; Gadat, S.; Valitutti, S.
10.1101/2020.09.08.287029 — immunology — Posted on 2020-12-30
137 In your phase: Neural phase synchronization underlies visual imagery of faces
Canales-Johnson, A.; Lanfranco, R. C.; Morales, J. P.; Martinez-Pernia, D.; Valdes, J.; Ezquerro-Nassar, A.; Rivera-Rei, A.; Ibanez, A.; Chennu, S.; Bekinschtein, T.; Huepe, D.; Noreika, V.
10.1101/762062 — neuroscience — Posted on 2020-12-30
138 Neonatal oxytocin impacts hippocampal network development and restores adult social memory in a mouse model of autism.
Bertoni, A.; Schaller, F.; Tyzio, R.; Gaillard, S.; Santini, F.; Xolin, M.; Diabira, D.; Vaidyanathan, R.; Matarazzo, V.; Medina, I.; Hammock, E.; Zhang, J.; Chini, B.; Gaiarsa, J.-L.; Muscatelli, F.
10.1101/2020.09.21.306217 — neuroscience — Posted on 2020-12-30
141 Evolution of primate protomusicality via locomotion
Schruth, D. M.; Templeton, C. N.; Holman, D. J.; Smith, E. A.
10.1101/2020.12.29.424766 — evolutionary biology — Posted on 2020-12-30
142 Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Trevino, A. E.; Muller, F.; Andersen, J.; Sundaram, L.; Kathiria, A.; Shcherbina, A.; Farh, K.; Chang, H. Y.; Pasca, A. M.; Kundaje, A.; Pasca, S. P.; Greenleaf, W. J.
10.1101/2020.12.29.424636 — neuroscience — Posted on 2020-12-30
149 Precision mapping of the mouse brain metabolome
Pang, H.; Li, J.-L.; Hu, X.-L.; Chen, F.; Gao, X.; Zacharias, L. G.; Cai, F.; DeBerardinis, R. J.; Sun, W.; Hu, Z.; Ge, W.-p.
10.1101/2020.12.28.424544 — neuroscience — Posted on 2020-12-29
153 IHR-PVS National Bridging Workshops, a tool to operationalize the collaboration between human and animal health while advancing sector-specific goals in countries
BELOT, G.; Caya, F.; Errecaborde, K.; Sreedharan, R.; Traore, T.; Lafia, B.; Skrypnyk, A.; Montabord, D.; Carron, M.; Corning, S.; Isla, N.; Schmidt, T.; Gongal, G.; Samhouri, D.; Xing, J.; Chungong, S.; de la Rocque, S.; Riviere-Cinnamond, A.; Perez-Guttierez, E.
10.1101/2020.12.29.424658 — scientific communication and education — Posted on 2020-12-29
155 C1q/CTRP1 exerts neuroprotective effects in TBI rats by regulating inflammation and autophagy
Pei, M.; Wang, C.; Li, Z.; Zhang, J.; Huang, P.; Wang, J.; Huang, J.; Zou, D.; Chen, Y.
10.1101/2020.12.29.424653 — pathology — Posted on 2020-12-29
158 Squid: Simplifying Quantitative Imaging Platform Development and Deployment
Li, H.; Krishnamurthy, D.; Li, E.; Vyas, P.; Akireddy, N.; Chai, C.; Prakash, M.
10.1101/2020.12.28.424613 — bioengineering — Posted on 2020-12-29
162 Lentiviral vector-based SARS-CoV-2 pseudovirus enables analysis of neutralizing activity in COVID-19 convalescent plasma
Pamukcu, C.; Celik, E.; Ergun, E. Z.; Karahan, Z. S.; Turkoz, G.; Aras, M.; Eren, C.; Sili, U.; Bilginer, H.; Suder, I.; Mandaci, B. C.; Dingiloglu, B.; Tatli, O.; Dinler Doganay, G.; Baris, S.; Ozoren, N.; Sutlu, T.
10.1101/2020.12.28.424590 — immunology — Posted on 2020-12-29
168 Blocking plasmodesmata in specific phloem cell types reduces axillary bud growth in Arabidopsis thaliana
Paterlini, A.; Dorussen, D.; Fichtner, F.; van Rongen, M.; Delacruz, R.; Vojnovic, A.; Helariutta, Y.; Leyser, O.
10.1101/2020.12.28.424434 — plant biology — Posted on 2020-12-29
169 Computational model investigates the evolution of colonic crypts during Lynch syndrome carcinogenesis
Haupt, S.; Gleim, N.; Ahadova, A.; Bläker, H.; von Knebel Doeberitz, M.; Kloor, M.; Heuveline, V.
10.1101/2020.12.29.424555 — cancer biology — Posted on 2020-12-29
170 Structural dynamics of the SARS-CoV-2 frameshift-stimulatory pseudoknot reveal topologically distinct conformers
Neupane, K.; Zhao, M.; Lyons, A.; Munshi, S.; Ileperuma, S. M.; Ritchie, D. B.; Hoffer, N. Q.; Narayan, A.; Woodside, M. T.
10.1101/2020.12.28.424630 — biophysics — Posted on 2020-12-29
171 neoDL: A novel neoantigen intrinsic feature-based deep learning model identifies IDH wild-type glioblastomas with the longest survival
Sun, T.; He, Y.; Li, W.; Liu, G.; Li, L.; Wang, L.; Xiao, Z.; Han, X.; Wen, H.; Liu, Y.; Chen, Y.; Wang, H.; Li, J.; Fan, Y.; Zhang, W.; Zhang, J.
10.1101/2020.12.28.424562 — bioinformatics — Posted on 2020-12-29
172 Amyloid fibril-based hydrogels for high-throughput tumor spheroid modeling
Singh, N.; Patel, K.; Navalkar, A.; Kadu, P.; Datta, D.; Chatterjee, D.; Shaw, A.; Jadhav, S.; Maji, S. K.
10.1101/2020.12.28.424634 — bioengineering — Posted on 2020-12-29
173 ACE2 peptide fragment interacts with several sites on the SARS-CoV-2 spike protein S1
Kuznetsov, A.; Arukuusk, P.; Härk, H.; Juronen, E.; Langel, U.; Ustav, M.; Järv, J.
10.1101/2020.12.29.424682 — biochemistry — Posted on 2020-12-29
175 Experimental assessment of K locus effects on the gray wolf response to virus
Johnston, R. A.; Rheinwald, J. G.; vonHoldt, B. M.; Stahler, D. R.; Lowry, W.; Tung, J.; Wayne, R. K.
10.1101/2020.12.29.424723 — evolutionary biology — Posted on 2020-12-29
180 Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients
Xiang, H.; Zhao, Y.; Li, X.; Liu, P.; Wang, L.; Wang, M.; Tian, L.; Sun, H.; Zhang, W.; Xu, Z.; Ye, B.; Yuan, X.; Wang, P.; Zhang, N.; Gong, Y.; Bian, C.; Wang, Z.; Yu, L.; Yan, J.; Meng, F.; Bai, C.; Wang, X.; Liu, X.; Gao, K.; Wu, L.; Liu, L. F.; Gu, Y.; Bi, Y. J.; Shi, Y.; Zhang, S.; Zhu, C.; Xu, X.; Wu, G.; Gao, G.; Yang, N.; Liu, W.; Yang, P.
10.1101/2020.12.28.424622 — immunology — Posted on 2020-12-29
182 Spectrum Degradation of Hippocampal LFP during Euthanasia
Zhou, Y.; Sheremet, A.; Kennedy, J. P.; Dicola, N. M.; Maciel, C.; Burke, S. N.; Maurer, A. P.
10.1101/2020.12.28.424611 — neuroscience — Posted on 2020-12-29
184 Neural dysfunction at the upper thermal limit in the zebrafish
Andreassen, A. H.; Hall, P.; Khatibzadeh, P.; Jutfelt, F.; Kermen, F.
10.1101/2020.12.28.424529 — neuroscience — Posted on 2020-12-29
186 GENERATION AND CHARACTERIZATION OF IMMORTALIZED MOUSE CORTICAL ASTROCYTES FROM WILDTYPE AND CONNEXIN43 KNOCKOUT MICE
Cibelli, A.; Lopez-Quintero, S. V.; McCutcheon, S.; Scemes, E.; Spray, D. C.; Stout, R. F.; Suadicani, S. O.; Thi, M. M.; Urban-Maldonado, M.
10.1101/2020.12.28.424504 — neuroscience — Posted on 2020-12-29
188 Rapid expression of COVID-19 proteins by transient expression in tobacco.
Lindsay, P. L.; Ackerman, A.; Jian, Y.; Artz, O.; Rosado, D.; Skopelitis, T.; Kitagawa, M.; Pedmale, U. V.; Jackson, D.
10.1101/2020.12.29.424712 — plant biology — Posted on 2020-12-29
189 Increased ketohexokinase-A governs fructose-induced podocyte hypertrophy by IL-6/STAT3 signaling activation
Zhou, J.; Zhang, D.-M.; Yang, J.; Ding, H.; Li, T.-S.; Liu, Z.-H.; Chen, L.; Jiao, R.-Q.; Kong, L.-D.
10.1101/2020.12.28.424520 — pathology — Posted on 2020-12-29
190 Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein
Gadhave, K.; Kumar, A.; Kumar, P.; Kapuganti, S. K.; Garg, N.; Vendruscolo, M.; Giri, R.
10.1101/2020.12.29.424646 — biophysics — Posted on 2020-12-29
192 Non-covalent TMPRSS2 inhibitors identified from virtual screening
Hu, X.; Shrimp, J. H.; Guo, H.; Zakharov, A. V.; Jain, S.; Shinn, P.; Simeonov, A.; Hall, M.; Shen, M.
10.1101/2020.12.28.424413 — bioinformatics — Posted on 2020-12-29
193 Fast end-to-end learning on protein surfaces
Sverrisson, F.; Feydy, J.; Correia, B.; Bronstein, M.
10.1101/2020.12.28.424589 — bioinformatics — Posted on 2020-12-29
194 Design of Specific Primer Set for Detection of B.1.1.7 SARS-CoV-2 Variant using Deep Learning
Lopez-Rincon, A.; Perez-Romero, C.; Tonda, A.; Mendoza-Maldonado, L.; Claassen, E.; Garssen, J.; Kraneveld, A. D.
10.1101/2020.12.29.424715 — bioinformatics — Posted on 2020-12-29
196 SARS-CoV-2 highly conserved s2m element dimerizes via a kissing complex and interacts with host miRNA-1307-3p
Imperatore, J. A.; Cunningham, C. L.; Pellegrene, K. A.; Brinson, R. G.; Marino, J. P.; Evanseck, J. D.; Mihailescu, M. R.
10.1101/2020.12.29.424733 — biochemistry — Posted on 2020-12-29
200 Single cell transcriptomic analyses reveal the impact of bHLH factors ATOH7 and Neurog2 on human retinal organoid development
Zhang, X.; Mandric, I.; Nguyen, K. H.; Nguyen, T. T. T.; Pellegrini, M.; Grove, J. C. R.; Barnes, S.; Yang, X.-J.
10.1101/2020.10.27.358135 — developmental biology — Posted on 2020-12-29
201 Genome-wide binding analyses of HOXB1 revealed a novel DNA binding motif associated with gene repression
Singh, N. P.; De Kumar, B.; Paulson, A.; Parrish, M.; Scott, C.; Zhang, Y.; Florens, L.; Krumlauf, R.
10.1101/2020.12.29.424720 — developmental biology — Posted on 2020-12-29
202 Defective NETs Clearance contributes to sustained FXII Activation in COVID-19-associated Pulmonary Thrombo-Inflammation
Frye, M.; Englert, H.; Rangaswamy, C.; Deppermann, C.; Sperhake, J.-P.; Krisp, C.; Schreier, D.; Gordon, E.; Konrath, S.; Haddad, M.; Pula, G.; Mailer, R.; Schlueter, H.; Langer, F.; Pueschel, K.; Panousis, K.; Stavrou, E.; Maas, C.; Renne, T.
10.1101/2020.12.29.424644 — molecular biology — Posted on 2020-12-29
203 IL-27R signaling serves as immunological checkpoint for NK cells to promote hepatocellular carcinoma
Aghayev, T.; Peshkova, I. O.; Mazitova, A. M.; Titerina, E. K.; Fatkhullina, A.; Campbell, K. S.; Grivennikov, S. I.; Koltsova, E. K.
10.1101/2020.12.28.424635 — immunology — Posted on 2020-12-29
204 Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence
Bullen, G.; Galson, J. D.; Villar, P.; Moreels, L.; Ledsgaard, L.; Mattiuzzo, G.; Hall, G.; Bentley, E. M.; Masters, E. W.; Tang, D.; Millett, S.; Tongue, D.; Brown, R.; Diamantopoulos, I.; Parthiban, K.; Tebbutt, C.; Leah, R.; Chaitanya, K.; Pazeraitis, D.; Surade, S. B.; Ashiru, O.; Crippa, L.; Cowan, R.; Bowler, M. W.; Campbell, J. I.; Lee, W.-Y. J.; Carr, M. D.; Matthews, D.; Pfeffer, P.; Hufton, S. E.; Sawmynaden, K.; Osbourn, J.; McCafferty, J.; Karatt-Vellatt, A.
10.1101/2020.12.29.424711 — immunology — Posted on 2020-12-29
205 Leukodystrophy resembling Vanishing White Matter Disease is recapitulated by brain-specific depletion of apoptosis regulator MCL-1
Cleveland, A. H.; Romero, A.; Alfonso Azcona, L.; Herrero, M.; Nikolova, V. D.; Moy, S.; Elroy-Stein, O.; Gama, V.; Gershon, T. R.
10.1101/2020.12.02.408138 — neuroscience — Posted on 2020-12-29
207 The biophysical basis of protein domain compatibility
Coyote-Maestas, W.; Nedrud, D.; Suma, A.; He, Y.; Matreyek, K. A.; Fowler, D. M.; Carnevale, V.; Myers, C. L.; Schmidt, D.
10.1101/2020.12.09.418442 — biophysics — Posted on 2020-12-29
208 Cell-type-specific alternative polyadenylation (APA) genes reveal the function of dynamic APA in complex tissues
Bai, Y.; Qin, Y.; Fan, Z.; Morrison, R. M.; Nam, K.; Zarour, H. M.; Koldamova, R.; Padiath, Q. S.; Kim, S.; Park, H. J.
10.1101/2020.07.30.229096 — bioinformatics — Posted on 2020-12-29
220 NanoFAST: Structure-based design of a small fluorogen-activating protein with only 98 amino acids
Mineev, K. S.; Goncharuk, S. A.; Goncharuk, M. V.; Povarova, N. V.; Baleeva, N. S.; Smirnov, A. Y.; Myasnyanko, I. N.; Ruchkin, D. A.; Bukhdruker, S.; Remeeva, A.; Mishin, A.; Borshchevskiy, V.; Gordeliy, V.; Arseniev, A. S.; Gorbachev, D. A.; Gavrikov, A. S.; Mishin, A. S.; Baranov, M. S.
10.1101/2020.12.29.424647 — biochemistry — Posted on 2020-12-29
221 High resolution copy number inference in cancer using short-molecule nanopore sequencing
Baslan, T.; Kovaka, S.; Sedlazeck, F. J.; Zhang, Y.; Wappel, R.; Lowe, S. J.; Goodwin, S.; Schatz, M. C.
10.1101/2020.12.28.424602 — genomics — Posted on 2020-12-29
223 A long reads-based de-novo assembly of the genome of the Arlee homozygous line reveals structural genome variation in rainbow trout
Gao, G.; Magadan, S.; Waldbieser, G. C.; Youngblood, R. C.; Wheeler, P. A.; Scheffler, B.; Thorgaard, G. H.; Palti, Y.
10.1101/2020.12.28.424581 — genomics — Posted on 2020-12-29
224 Engineering large chromosomal deletions by CRISPR-Cas9
Eleveld, T. F.; Bakali, C.; Eijk, P. P.; Stathi, P.; Poddighe, P. J.; Ylstra, B.
10.1101/2020.12.29.424675 — genetics — Posted on 2020-12-29
225 Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in C. elegans
Levi-Ferber, M.; Shalash, R.; Le-Thomas, A.; Salzberg, Y.; Shurgi, M.; Ashkenazi, A.; Henis-Korenblit, S.
10.1101/2020.12.29.424718 — cell biology — Posted on 2020-12-29
226 A cryptic BRCA2 repeated motif binds to HSF2BP oligomers with no impact on meiotic recombination
Ghouil, R.; Miron, S.; Koornneef, L.; Veerman, J.; Paul, M. W.; Le Du, M.-H.; Sleddens-Linkels, E.; van Rossum-Fikkert, S. E.; van Loon, Y.; Felipe-Medina, N.; Pendas, A. M.; Maas, A.; Essers, J.; Legrand, P.; Baarends, W. M.; Kanaar, R.; Zinn-Justin, S.; Zelensky, A. N.
10.1101/2020.12.29.424679 — molecular biology — Posted on 2020-12-29
227 Investigating expression of a human optimized cas9 transgene in Neurospora crassa
Burrell, N.; Rhoades, N.; Boyd, A.; Mierendorf, J.; Yusifov, A.; Harvey, A.; Edwards, K.; Vogel, L.; Hammond, T. M.
10.1101/2020.12.29.424703 — molecular biology — Posted on 2020-12-29
231 Large palindromes on the primate X Chromosome are preserved by natural selection
Jackson, E. K.; Bellott, D. W.; Cho, T.-J.; Skaletsky, H.; Hughes, J.; Pyntikova, T.; Page, D. C.
10.1101/2020.12.29.424738 — genomics — Posted on 2020-12-29
233 Serotonin 2A receptor signaling coordinates central metabolic processes to modulate aging in response to nutrient choice
Lyu, Y.; Weaver, K. J.; Shaukat, H. A.; Plumhoff, M. L.; Tjilos, M.; Promislow, D. E.; Pletcher, S. D.
10.1101/2020.12.28.424627 — genetics — Posted on 2020-12-29
234 ADP-ribosylation of mitochondrial proteins is mediated by Neuralized-like protein 4 (NEURL4)
Cardamone, M. D.; Gao, Y.; Kwan, J.; Hayashi, V.; Sheeran, M.; Xu, J.; English, J.; Orofino, J.; Emili, A.; Perissi, V.
10.1101/2020.12.28.424513 — cell biology — Posted on 2020-12-29
236 Hsp70 chaperons TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation
Gu, J.; Wang, C.; Hu, R.; Li, Y.; Zhang, S.; Sun, Y.; Wang, Q.; Li, D.; Fang, Y.; Liu, C.
10.1101/2020.12.29.424685 — cell biology — Posted on 2020-12-29
237 Modular deep learning enables automated identification of monoclonal cell lines
Fischbacher, B.; Hedaya, S.; Hartley, B. J.; Wang, Z.; Lallos, G.; Hutson, D.; Zimmer, M.; Brammer, J.; The NYSCF Global Stem Cell Array Team, ; Paull, D.
10.1101/2020.12.28.424610 — cell biology — Posted on 2020-12-29
239 An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis
Wilson, M. M.; Callens, C.; Le Gallo, M.; Mironov, S.; Ding, Q.; Salamagnon, A.; Chavarria, T.; Peasah, A.; Bhutkar, A.; Martin, S.; Godey, F.; Tas, P.; Jetten, A.; Visvader, J. E.; Weinberg, R.; Attanasio, M.; Prigent, C.; Lees, J.; Guen, V.
10.1101/2020.12.29.424695 — cell biology — Posted on 2020-12-29
241 Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
Demo, G.; Loveland, A. B.; Svidritskiy, E.; Gamper, H. B.; Hou, Y.-M.; Korostelev, A. A.
10.1101/2020.12.29.424751 — molecular biology — Posted on 2020-12-29
243 Paired SARS CoV-2 Spike Protein Mutations Observed During Ongoing SARS-CoV-2 Viral Transfer from Humans to Minks and Back to Humans
Rubsamen, R.; Burkholz, S.; Pokhrel, S.; Kraemer, B. R.; Mochly-Rosen, D.; Carback, R. T.; Hodge, T.; Harris, P.; Ciotlos, S.; Wang, L.; Herst, C.
10.1101/2020.12.22.424003 — genetics — Posted on 2020-12-29
247 Neural precursor cells contribute to decision-making by tuning striatal connectivity via secretion of IGFBPL-1
Butti, E.; Cattaneo, S.; Bacigaluppi, M.; Cambiaghi, M.; Scotti, G.; Brambilla, E.; Sferruzza, G.; Ripamonti, M.; Simeoni, F.; Cacciaguerra, L.; Zanghi, A.; Quattrini, A.; Fesce, R.; Panina Bordignon, P.; Giannese, F.; Cittaro, D.; Kuhlmann, T.; D'Adamo, P.; Rocca, M. A.; Taverna, S.; Martino, G.
10.1101/2020.12.29.424678 — neuroscience — Posted on 2020-12-29
248 Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin
Khelashvili, G.; Pillai, A. N.; Lee, J.; Pandey, K.; Payne, A. M.; Siegel, Z.; Cuendet, M. A.; Lewis, T. R.; Arshavsky, V. Y.; Broichhagen, J.; Levitz, J.; Menon, A. K.
10.1101/2020.12.28.424580 — biophysics — Posted on 2020-12-29
249 Horizontal and vertical transmission of transgenerational memories via the Cer1 transposon
Moore, R. S.; Kaletsky, R.; Lesnik, C.; Cota, V.; Blackman, E.; Parsons, L. R.; Gitai, Z.; Murphy, C. T.
10.1101/2020.12.28.424563 — genetics — Posted on 2020-12-29
250 Mitochondrial introgression by ancient admixture between two distant lacustrine fishes in Sulawesi Island
Horoiwa, M.; Mandagi, I. F.; Sutra, N.; Montenegro, J.; Tantu, F. Y.; Masengi, K. W. A.; Nagano, A. J.; Kusumi, J.; Yasuda, N.; Yamahira, K.
10.1101/2020.12.29.424662 — evolutionary biology — Posted on 2020-12-29
253 Non-dietary Fructose Metabolism Contributes to the Warburg effect in Cancers
HAN, B.; Wang, L.; Wei, M.; Rajani, C.; Wei, R.; Wang, J.; Yang, H.; Carbone, M.; Xie, G.; jia, w.
10.1101/2020.06.04.132902 — cancer biology — Posted on 2020-12-29
257 Wild emmer introgressions alter root-to-shoot growth dynamics in response to water stress
Bacher, H.; Zhu, f.; Gao, T.; Liu, K.; Dhatt, B.; Awada, T.; Zhang, C.; Distelfeld, A.; Yu, H.; Peleg, Z.; Walia, H.
10.1101/2020.06.17.157461 — plant biology — Posted on 2020-12-29
258 Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9
Yang, S.; Park, D.; Manning, L.; Hill, S. E.; Cao, M.; Xuan, Z.; Gonzalez, I.; Shao, L.; Okeke, I.; De Camilli, P.; Colon-Ramos, D.
10.1101/2020.12.28.424508 — neuroscience — Posted on 2020-12-28
260 An NF-κB/IRF1 axis programs cDC1s to drive anti-tumor immunity
Ghislat, G.; Cheema, A. S.; Baudoin, E.; Verthuy, C.; Ballester, P.; Crozat, K.; Attaf, N.; Dong, C.; Milpied, P.; Malissen, B.; Auphan-Anezin, N.; Manh, T.-P. V.; Dalod, M.; Lawrence, T.
10.1101/2020.12.28.424621 — immunology — Posted on 2020-12-28
266 Single-cell Individual Complete mtDNA Sequencing Uncovers Hidden Mitochondrial Heterogeneity in Human and Mouse Oocytes
Bi, C.; Wang, L.; Fan, Y.; Ramos-Mandujano, G.; Yuan, B.; Zhou, X.; Wang, J.; Shao, Y.; Zhang, P.-Y.; Huang, Y.; Yu, Y.; Izpisua Belmonte, J. C.; Li, M.
10.1101/2020.12.28.424537 — genomics — Posted on 2020-12-28
268 The N-terminal Tail of C. elegans CENP-A Interacts with KNL-2 and is Essential for Centromeric Chromatin Assembly
de Groot, C.; Houston, J.; Davis, B.; Gerson-Gurwitz, A.; Monen, J.; Oegema, K.; Shiau, A. K.; Desai, A.
10.1101/2020.12.28.424576 — cell biology — Posted on 2020-12-28
274 Novel integrative elements and genomic plasticity in ocean ecosystems
Hackl, T.; Laurenceau, R.; Ankenbrand, M. J.; Bliem, C.; Cariani, Z.; Thomas, E.; Dooley, K. D.; Arellano, A. A.; Hogle, S. L.; Berube, P.; Leventhal, G. E.; Luo, E.; Eppley, J.; Zayed, A. A.; Beaulaurier, J.; Stepanauskas, R.; Sullivan, M. B.; DeLong, E. F.; Biller, S. J.; Chisholm, S. W.
10.1101/2020.12.28.424599 — microbiology — Posted on 2020-12-28
275 Rapid inactivation in vitro of SARS-CoV-2 in saliva by black tea and green tea
Ohgitani, E.; Shin-Ya, M.; Ichitani, M.; Kobayashi, M.; Takihara, T.; Kawamoto, M.; Kinugasa, H.; Mazda, O.
10.1101/2020.12.28.424533 — microbiology — Posted on 2020-12-28
276 The replication of the human respiratory syncytial virus in a T cell line has multiple ineffective steps
de Souza Cardoso, R.; Coelho, A. C. L.; de Jesus, B. L. S.; Vitti, B. C.; Souza, J. d. P.; Viana, R. M. M.; Pontelli, M. C.; Murakami, T.; Ventura, A. M.; Ono, A.; Arruda, E.
10.1101/2020.12.28.424605 — microbiology — Posted on 2020-12-28
278 Cortical layer-specific modulation of neuronal activity after sensory deprivation due to spinal cord injury
Zaforas, M.; Rosa, J. M.; Alonso-Calvino, E.; Fernandez-Lopez, E.; Miguel-Quesada, C.; Oliviero, A.; Aguilar, J.
10.1101/2020.12.28.424612 — neuroscience — Posted on 2020-12-28
280 ZIKV disrupts fetal outcome, placental ultrastructure and drug transporter expression in mice
Andrade, C. B. V.; Monteiro, V. R. S.; Coelho, S. V. A.; Gomes, H. R.; Sousa, R. P. C.; Nascimento, V. M. O.; Bloise, F. F.; Matthews, S. G.; Bloise, E.; Arruda, L. B.; Ortiga-Carvalho, T. M.
10.1101/2020.12.17.423218 — physiology — Posted on 2020-12-28
282 An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML
Lin, S.; Larrue, C.; Seong, B. K. A.; Dharia, N. V.; Kuljanin, M.; Wechsler, C.; Kugener, G.; Robichaud, A.; Conway, A.; Mashaka, T. N.; Mouche, S.; Adane, B.; Ryan, J.; Mancias, J. D.; Younger, S. T.; Piccioni, F.; Lee, L.; Wunderlich, M.; Letai, A.; Tamburini, J.; Stegmaier, K.
10.1101/2020.12.28.424340 — cancer biology — Posted on 2020-12-28
285 Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting its Protein-Protein Interactions
Bobone, S.; Pannone, L.; Biondi, B.; Solman, M.; Flex, E.; Canale, V.; Calligari, P.; De Faveri, C.; Gandini, T.; Quercioli, A.; Torini, G.; Venditti, M.; Lauri, A.; Fasano, G.; Hoeksma, J.; Santucci, V.; Cattani, G.; Bocedi, A.; Carpentieri, G.; Tirelli, V.; Sanchez, M.; Peggion, C.; Formaggio, F.; Den Hertog, J.; Martinelli, S.; Bocchinfuso, G.; Tartaglia, M.; Stella, L.
10.1101/2020.08.28.271809 — biophysics — Posted on 2020-12-28
287 Analysis and Forecasting of Global of RT-PCR Primers for SARS-CoV-2
Nayar, G.; Seabolt, E.; Kunitomi, M.; Agarwal, A.; Beck, K. L.; Mukherjee, V.; Kaufman, J.
10.1101/2020.12.26.424429 — bioinformatics — Posted on 2020-12-28
289 Chromosomal rearrangements represent modular cassettes for local adaptation across different geographic scales
Merot, C.; Berdan, E.; Cayuela, H.; Djambazian, H.; Ferchaud, A.-L.; Laporte, M.; Normandeau, E.; Ragoussis, J.; Wellenreuther, M.; Bernatchez, L.
10.1101/2020.12.28.424584 — evolutionary biology — Posted on 2020-12-28
290 SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity
Ramirez, C.; Kumar Sharma, A.; Kee, C.; Thomas, L.; Boulant, S.; Herrmann, C.
10.1101/2020.12.28.424029 — cell biology — Posted on 2020-12-28
291 The comprehensive roadmaps of reprogramming and transformation unveiled antagonistic roles for bHLH transcription factors in the control of cellular plasticity
Huyghe, A.; Furlan, G.; Schroeder, J.; Studer, F.; Mugnier, F.; de Matteo, L.; Wang, J.; Yu, Y.; Rama, N.; Gibert, B.; Wajda, P.; Goddard, I.; Gadot, N.; Brevet, M.; Siouda, M.; Mulligan, P.; Dante, R.; Liu, P.; Gronemeyer, H.; Mendoza-Parra, M. A.; Polo, J. M.; Lavial, F.
10.1101/2020.12.28.424606 — cell biology — Posted on 2020-12-28
293 A comprehensive motifs-based interactome of the C/EBPα transcription factor
Ramberger, E.; Sapozhnikova, V.; Kowenz-Leutz, E.; Zimmermann, K.; Nicot, N.; Nazarov, P. V.; Perez-Hernandez, D.; Reimer, U.; Mertins, P.; Dittmar, G.; Leutz, A.
10.1101/2020.12.28.424569 — molecular biology — Posted on 2020-12-28
294 ADH5-mediated NO Bioactivity Maintains Metabolic Homeostasis in Brown Adipose Tissue
Sebag, S. C.; Zhang, Z.; Qian, Q.; Harata, M.; Li, M.; Li, W.; Zhu, Z.; Zingman, L.; Liu, L.; Lira, V. A.; Potthoff, M. J.; Bartelt, A.; Yang, L.
10.1101/2020.12.27.424489 — molecular biology — Posted on 2020-12-28
295 Comprehensive label-free characterization of extracellular vesicles and their surface proteins
Priglinger, E.; Strasser, J.; Buchroithner, B.; Weber, F.; Wolbank, S.; Auer, D.; Grasmann, E.; Arzt, C.; Narzt, M. S.; Grillari, J.; Preiner, J.; Jacak, J.; Gimona, M.
10.1101/2020.12.28.424566 — molecular biology — Posted on 2020-12-28
297 The Diversity and Evolution of Microbial Dissimilatory Phosphite Oxidation
Ewens, S. D.; Gomberg, A.; Barnum, T.; Borton, M.; Carlson, H.; Wrighton, K.; Coates, J.
10.1101/2020.12.28.424620 — microbiology — Posted on 2020-12-28
299 Adaptation to host cell environment during experimental evolution of Zika virus
Grass, V.; Hardy, E.; Kobert, K.; Talemi, S. R.; Decembre, E.; Guy, C.; Markov, P. V.; Kohl, A.; Paris, M.; Böckmann, A.; Munoz-Gonzalez, S.; Sherry, L.; Höfer, T.; Boussau, B.; Dreux, M.
10.1101/2020.12.28.424577 — microbiology — Posted on 2020-12-28
301 A prevalent focused human antibody response to the influenza hemagglutinin head interface
McCarthy, K. R.; Lee, J.; Watanabe, A.; Kuraoka, M.; Robinson-McCarthy, L. R.; Georgiou, G.; Kelsoe, G.; Harrison, S.
10.1101/2020.12.28.424595 — immunology — Posted on 2020-12-28
302 Acute lymph node slices are a functional model system to study immunity ex vivo
Belanger, M. C.; Ball, A. G.; Catterton, M. A.; Kinman, A. W. L.; Anbaei, P.; Groff, B. D.; Melchor, S. J.; Lukens, J. R.; Ross, A. E.; Pompano, R. R.
10.1101/865543 — immunology — Posted on 2020-12-28
307 Novel insights into the mode of action of 1,4-dioxane using a systems screening approach
Vasiliou, V.; Charkoftaki, G.; Golla, J. P.; Santos-Neto, A.; Orlicky, D. J.; Garcia-Milian, R.; Chen, Y.; Rattray, N. J. W.; Cai, Y.; Wang, Y.; Shern, C. T.; Mironova, V.; Wang, Y.; Johnson, C. H.; Thompson, D. C.
10.1101/2020.12.27.424470 — pharmacology and toxicology — Posted on 2020-12-28
308 Acquired RAD51C promoter methylation loss causes PARP inhibitor resistance in high grade serous ovarian carcinoma
Nesic, K.; Kondrashova, O.; Hurley, R. M.; McGehee, C.; Vandenberg, C. J.; Ho, G.-Y.; Lieschke, E.; Dall, G.; Bound, N.; Shield-Artin, K.; Radke, M. R.; Musafer, A.; Qing Chai, Z.; Eftekhariyan Ghamsari, M. R.; Harrell, M. I.; Kee, D.; Olesen, I.; McNally, O.; Traficante, N.; DeFazio, A.; Bowtell, D.; Swisher, E. M.; Weroha, J.; Nones, K.; Waddell, N.; Kaufmann, S. H.; Dobrovic, A.; Wakefield, M. J.; Scott, C. L.
10.1101/2020.12.10.419176 — cancer biology — Posted on 2020-12-28
309 Single cell gene fusion detection by scFusion
Jin, Z.; Huang, W.; Shen, N.; Li, J.; Wang, X.; Park, P. J.; Xi, R.
10.1101/2020.12.27.424506 — bioinformatics — Posted on 2020-12-28
317 Quantification of Microtubule Stutters: Dynamic Instability Behaviors that are Strongly Associated with Catastrophe
Mahserejian, S. M.; Scripture, J. P.; Mauro, A. J.; Lawrence, E. J.; Jonasson, E. M.; Murray, K. S.; Li, J.; Gardner, M. K.; Alber, M.; Zanic, M.; Goodson, H. V.
10.1101/2019.12.16.878603 — cell biology — Posted on 2020-12-28
319 Age-related Impairment of Implant Osseointegration is Associated with Immune Activation and Suppression of Angiogenic, Notch, and Wnt Pathways
Turajane, K.; Ji, G.; Chinenov, Y.; Chao, M.; Ayturk, U. M.; Greenblatt, M. B.; Ivashkiv, L. B.; Bostrom, M. P. G.; Yang, X.
10.1101/2020.12.27.424462 — immunology — Posted on 2020-12-28
320 The autophagy activator Spermidine ameliorates Alzheimer's disease pathology and neuroinflammation in mice
Freitag, K.; Sterczyk, N.; Schulz, J.; Houtman, J.; Fleck, L.; Sigrist, S. J.; Heppner, F. L.; Jendrach, M.
10.1101/2020.12.27.424477 — neuroscience — Posted on 2020-12-28
321 Conflict-mediated tasks for studying the act of facing threats in pursuit of rewards
Illescas-Huerta, E.; Ramirez-Lugo, L.; Ordonez Sierra, R.; Quillfeldt, J. A.; Sotres-Bayon, F.
10.1101/2020.12.27.424515 — neuroscience — Posted on 2020-12-28
323 Open-top axially swept light sheet microscopy
Kim, B.; Na, M.; Park, S.; Kim, K.; Park, J.-H.; Chung, E.; Chang, S.; Kim, K. H.
10.1101/2020.12.27.424265 — neuroscience — Posted on 2020-12-28
325 Biological Correlations and Confounding Variables for Quantification of Retinal Ganglion Cells Based on Optical Coherence Tomography Using Diversity Outbred Mice
Hedberg-Buenz, A.; Meyer, K. J.; van der Heide, C. J.; Deng, W.; Lee, K.; Soukup, D. A.; Kettelson, M.; Pellack, D.; Mercer, H.; Wang, K.; Garvin, M. K.; Abramoff, M. D.; Anderson, M. G.
10.1101/2020.12.23.423848 — neuroscience — Posted on 2020-12-28
326 Activation of TIR signaling is required for pattern-triggered immunity
Tian, H.; Chen, S.; Wu, Z.; Ao, K.; Yaghmaiean, H.; Sun, T.; Huang, W.; Xu, F.; Zhang, Y.; Wang, S.; Li, X.; Zhang, Y.
10.1101/2020.12.27.424494 — plant biology — Posted on 2020-12-28
327 Feasibility and safety of a telemetric pulmonary artery pressure monitoring system in acute and chronic porcine models of pulmonary hypertension.
Rothman, A. M. K.; Arnold, N. D.; Abou-Hanna, J.; Forouzan, O.; Middleton, J. T.; Zafar, H.; Swift, A. J.; Dahaghin, P.; Konganige, S.; Suvarna, S. k.; Kiely, D. G.; Gunn, J.
10.1101/2020.12.27.424411 — physiology — Posted on 2020-12-28
329 CKS1-dependent proteostatic regulation has dual roles combating acute myeloid leukemia whilst protecting normal hematopoiesis
Grey, W.; Rio-Machin, A.; Casado-Izquierdo, P.; Miettinen, J.; Copley, F.; Parsons, A.; Heckman, C.; Cutillas, P.; Gribben, J.; Fitzgibbon, J.; Bonnet, D.
10.1101/2020.12.27.423419 — cancer biology — Posted on 2020-12-28
333 SARS-CoV-2 disease severity and transmission efficiency is increased for airborne but not fomite exposure in Syrian hamsters
Port, J. R.; Yinda, C. K.; Offei Owusu, I.; Holbrook, M.; Fischer, R. J.; Bushmaker, T. J.; Avanzato, V. A.; Schulz, J. E.; van Doremalen, N.; Clancy, C.; Munster, V.
10.1101/2020.12.28.424565 — microbiology — Posted on 2020-12-28
334 SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma
Andreano, E.; Piccini, G.; Licastro, D.; Casalino, L.; Johnson, N. V.; Paciello, I.; Dal Monego, S.; Pantano, E.; Manganaro, N.; Manenti, A.; Manna, R.; Casa, E.; Hyseni, I.; Benincasa, L.; Montomoli, E.; Amaro, R. E.; McLellan, J. S.; Rappuoli, R.
10.1101/2020.12.28.424451 — immunology — Posted on 2020-12-28
335 Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection
Winkler, E. S.; Gilchuk, P.; Yu, J.; Bailey, A. L.; Chen, R. E.; Zost, S. J.; Jang, H.; Huang, Y.; Allen, J. D.; Case, J. B.; Sutton, R. E.; Carnahan, R. H.; Darling, T. L.; Boon, A. C. M.; Mack, M.; Head, R. D.; Ross, T. M.; Crowe, J. E.; Diamond, M.
10.1101/2020.12.28.424554 — immunology — Posted on 2020-12-28
337 Losartan promotes cell survival following SARS-CoV-2 infection in vitro
Nejat, R.; Sadr, A. S.; Freitas, B. T.; Crabtree, J.; Pegan, S. D.; Tripp, R. A.; Najafi, D. J.
10.1101/2020.12.27.424507 — pharmacology and toxicology — Posted on 2020-12-28
338 Therapeutic vulnerability to PARP1/2 inhibition in RB1-mutant osteosarcoma
Zoumpoulidou, G.; Mendoza, C. A.; Mancusi, C.; Ahmed, R. M.; Denman, M.; Steele, C. D.; Manji, J.; Pillay, N.; Strauss, S. J.; Mittnacht, S.
10.1101/2020.12.28.424497 — cancer biology — Posted on 2020-12-28
339 Identification of proximal SUMO-dependent interactors using SUMO-ID
Barroso-Gomila, O.; Trulsson, F.; Muratore, V.; Canosa, I.; Cortazar, A. R.; Perez, C.; Azkargorta, M.; Iloro, I.; Carracedo, A.; Aransay, A. M.; Elortza, F.; Mayor, U.; Vertegaal, A. C. O.; Barrio, R.; Sutherland, J. D.
10.1101/2020.12.28.424528 — biochemistry — Posted on 2020-12-28
342 Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice
Martino, N.; Bossardi Ramos, R.; Lu, S.; Leyden, K.; Tomaszek, L.; Jaitovich, A.; Vincent, P. A.; Adam, A. P.
10.1101/2020.12.28.424586 — cell biology — Posted on 2020-12-28
351 Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas
Wang, H.; Lu, J.; Mandel, J. A.; Zhang, W.; Schwalbe, M.; Gorka, J.; Liu, Y.; Marburger, B.; Wang, J.; Ranganathan, S.; Prochownik, E. V.
10.1101/2020.09.13.295311 — cancer biology — Posted on 2020-12-28
354 SARS-CoV-2 Genomic Surveillance in Costa Rica: Evidence of a Divergent Population and an Increased Detection of a Spike T1117I Mutation
Molina Mora, J. A.; Cordero-Laurent, E.; Godinez, A.; Calderon, M.; Brenes, H.; Soto-Garita, C.; Perez-Corrales, C.; COINGESA-CR Consorcio Interinstitucional de Estudios Genomicos del SARS-CoV-2 Costa Rica, ; Drexler, J. F.; Moreira-Soto, A.; Corrales-Aguilar, E.; Duarte-Martinez, F.
10.1101/2020.12.21.423850 — genomics — Posted on 2020-12-28
355 Potential role of host-mediated RNA editing in intra-host variability of SARS-CoV-2 genomes
Pathak, A. K.; Fatihi, S.; Abbas, T.; Uppili, B.; Mishra, G. P.; Ghosh, A.; Banu, S.; Bhoyar, R. C.; Jain, A.; Divakar, M. K.; Imran, M.; Faruq, M.; Sowpati, D. T.; Raghav, S. K.; Thukral, L.; Mukerji, M.
10.1101/2020.12.09.417519 — genomics — Posted on 2020-12-28
356 A novel family of secreted proteins linked to plant gall development
Korgaonkar, A.; Han, C.; Lemire, A. L.; Siwanowicz, I.; Bennouna, D.; Kopec, R.; Andolfatto, P.; Shigenobu, S.; Stern, D. L.
10.1101/2020.10.28.359562 — genetics — Posted on 2020-12-28
358 Making the invisible enemy visible
Croll, T.; Diederichs, K.; Fischer, F.; Fyfe, C.; Gao, Y.; Horrell, S.; Joseph, A. P.; Kandler, L.; Kippes, O.; Kirsten, F.; Müller, K.; Nolte, K.; Payne, A.; Reeves, M. G.; Richardson, J.; Santoni, G.; Stäb, S.; Tronrud, D.; von Soosten, L.; Williams, C.; Thorn, A.
10.1101/2020.10.07.307546 — molecular biology — Posted on 2020-12-28
359 IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition
Prelli Bozzo, C.; Nchioua, R.; Volcic, M.; Krueger, J.; Heller, S.; Stuerzel, C. M.; Kmiec, D.; Conzelmann, C.; Mueller, J. A.; Zech, F.; Schuetz, D.; Koepke, L.; Braun, E.; Gross, R.; Wettstein, L.; Weil, T.; Weiss, J.; Sauter, D.; Muench, J.; Diofano, F.; Goffinet, C.; Catanese, A.; Schoen, M.; Boeckers, T.; Stenger, S.; Sato, K.; Just, S.; Kleger, A.; Sparrer, K. M. J.; Kirchhoff, F.
10.1101/2020.08.18.255935 — microbiology — Posted on 2020-12-28
361 Physiology and function of PNS axons rely on glycolic metabolism in myelinating Schwann cells
DECK, M.; Van Hameren, G.; Campbell, G.; Bernard-Marissal, N.; Devaux, J.; Berthelot, J.; Lattard, A.; Medard, J.-J.; Gautier, B.; Quintana, P.; Chao De La Barca, J. M.; Reynier, P.; Lenaers, G.; Chrast, R.; Tricaud, N.
10.1101/2020.04.23.049056 — neuroscience — Posted on 2020-12-28
364 Extracellular Vesicles Analysis in the COVID-19 Era: Insights on Serum Inactivation Protocols Towards Downstream Isolation and Analysis
Frigerio, R.; Musico, A.; Brucale, M.; Ridolfi, A.; Galbiati, S.; Vago, R.; Bergamaschi, G.; Ferretti, A.; Chiari, M.; Valle, F.; Gori, A.; Cretich, M.
10.1101/2020.12.10.417758 — biochemistry — Posted on 2020-12-28
365 Lateral Hypothalamic GABAergic neurons encode and potentiate sucrose palatability
Garcia, A.; Coss, A.; Luis-Islas, J.; Puron-Sierra, L.; Luna, M.; Villavicencio, M.; Gutierrez, R.
10.1101/2020.06.30.180646 — neuroscience — Posted on 2020-12-27
366 Functional dissection of neural circuitry using a genetic reporter for fMRI
Ghosh, S.; Li, N.; Bartelle, B. B.; Xie, T.; Daher, J. I.; Singh, U. D.; Xie, K.; DiNapoli, N.; Evans, N. B.; Chung, K.; Jasanoff, A. P.
10.1101/2020.12.27.424403 — neuroscience — Posted on 2020-12-28
367 Sparse Epistatic Regularization of Deep Neural Networks for Inferring Fitness Functions
Aghazadeh, A.; Nisonoff, H.; Ocal, O.; Huang, Y.; Koyluoglu, O. O.; Listgarten, J.; Ramchandran, K.
10.1101/2020.11.24.396994 — bioinformatics — Posted on 2020-12-27
368 Systematic evaluation of chromosome conformation capture assays
Akgol Oksuz, B.; Yang, L.; Abraham, S.; Venev, S. V.; Krietenstein, N.; Parsi, K. M.; Ozadam, H.; Oomen, M. E.; Nand, A.; Mao, H.; Genga, R. M. J.; Maehr, R.; Rando, O.; Mirny, L.; Gibcus, J. H.; Dekker, J.
10.1101/2020.12.26.424448 — genomics — Posted on 2020-12-27
369 A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs
Nguyen, T.; Phan, K. L.; Kreitler, D. F.; Andrews, L. C.; Gabelli, S. B.; Kozakov, D.; Jakoncic, J.; Sweet, R. M.; Soares, A.; Bernstein, H. J.
10.1101/2020.12.14.422680 — molecular biology — Posted on 2020-12-27
371 A parental transcriptional response to microsporidia infection induces inherited immunity in offspring
Willis, A. R.; Zhao, W.; Sukhdeo, R.; Wadi, L.; Tamim El Jarkass, H.; Claycomb, J. M.; Reinke, A. W.
10.1101/2020.10.11.335117 — microbiology — Posted on 2020-12-27
372 The infection-tolerant mammalian reservoir of Lyme disease and other zoonoses broadly counters the inflammatory effects of endotoxin
Balderrama-Gutierrez, G.; Milovic, A.; Cook, V. J.; Islam, M. N.; Zhang, Y.; Kiaris, H.; Belisle, J. T.; Mortazavi, A.; Barbour, A. G.
10.1101/2020.12.13.422519 — systems biology — Posted on 2020-12-27
375 delta-Melt: Nucleic acid conformational penalties from melting experiments
Rangadurai, A.; Shi, H.; Xu, Y.; Liu, B.; Abou Assi, H.; Zhou, H.; Kimsey, I. J.; Al-Hashimi, H. M.
10.1101/2020.12.26.424438 — biophysics — Posted on 2020-12-27
385 Deciphering colchicine like actions of clerodin in terms of microtubule destabilization based mitotic abnormalities, G2/M-phase arrest, and plant polyploidy
Roy, S.; Kundu, L. M.; Roy, G. C.; Barmana, M.; Chakrabortya, T.; Ghosh, P.; Das, R.; Tripathy, D.; Singh, N.; Banerjee, S.; Bhattacharjee, A.; Pal, A.; Chatterjee, A.; Ray, S.
10.1101/2020.12.27.424481 — cell biology — Posted on 2020-12-27
392 IWS1 phosphorylation by AKT kinase controls the nucleocytoplasmic export of type I IFNs and the sensitivity of lung adenocarcinoma cells to oncolytic viral infection, through U2AF2 RNA splicing.
Laliotis, G. I.; Kenney, A.; Chavdoula, E.; Orlacchio, A.; Kaba, A. K.; La Ferlita, A.; Anastas, V.; Tsatsanis, C.; Beane, J. D.; Sehgal, L.; Coppola, V.; Yount, J. S.; Tsichlis, P. N.
10.1101/2020.12.26.424461 — cancer biology — Posted on 2020-12-27
393 The neutralization effect of Montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies
Durdagi, S.; Avsar, T.; Orhan, M. D.; Serhatli, M.; Balcioglu, B. K.; Ozturk, H. U.; Kayabolen, A.; Cetin, Y.; Aydinlik, S.; Bagci-Onder, T.; Tekin, S.; Demirci, H.; Guzel, M.; Akdemir, A.; Calis, S.; Oktay, L.; Tolu, I.; Butun, Y. E.; Erdemoglu, E.; Olkan, A.; Tokay, N.; Isik, S.; Ozcan, A.; Acar, E.; Buyukkilic, S.; Yumak, Y.
10.1101/2020.12.26.424423 — biophysics — Posted on 2020-12-27
394 Curvature of the retroviral capsid assembly is modulated by a molecular switch
Thame, T.; Alexander, B.; Qiao, X.; Jeon, J.; Weed, R.; Janicki, K.; Hu, B.; Gorkov, P. L.; Hung, I.; Gan, Z.; Perilla, J. R.; Chen, B.
10.1101/2020.12.26.424437 — biophysics — Posted on 2020-12-27
398 Genome Wide Characterization, Identification And Expression Analysis Of Erf Gene Family In Cotton
Zafar, M. M.; Rehman, A.; Razzaq, A.; Parvaiz, A.; Mustafa, G.; Mo, H.; Youlu, Y.; Shakeel, A.; Ren, M.
10.1101/2020.12.26.423497 — bioinformatics — Posted on 2020-12-27
399 Artificial Antigen Presenting Cells for Detection and Desensitisation of Auto-reactive T cells Associated with Type 1 Diabetes
Artzy-Schnirman, A.; Abu-Shah, E.; Chandrawati, R.; Altman, E.; Yusuf, N.; Wang, S.-T.; Ramos, J.; Hansel, C.; Haus-cohen, M.; Dahan, R.; Arif, S.; Dustin, M. L.; Peakman, M.; Reiter, Y.; Stevens, M. M.
10.1101/2020.12.26.424333 — bioengineering — Posted on 2020-12-27
400 The mechanism of SARS-CoV-2 nucleocapsid protein recognition by the human 14-3-3 proteins
Tugaeva, K. V.; Hawkins, D. E. D. P.; Smith, J. L. R.; Bayfield, O. W.; Ker, D.-S.; Sysoev, A. A.; Klychnikov, O. I.; Antson, A. A.; Sluchanko, N. N.
10.1101/2020.12.26.424450 — biochemistry — Posted on 2020-12-27
403 Systematic evaluation of chromosome conformation capture assays
Akgol Oksuz, B.; Yang, L.; Abraham, S.; Venev, S. V.; Krietenstein, N.; Parsi, K. M.; Ozadam, H.; Oomen, M. E.; Nand, A.; Mao, H.; Genga, R. M. J.; Maehr, R.; Rando, O.; Mirny, L.; Gibcus, J. H.; Dekker, J.
10.1101/2020.12.26.424448 — genomics — Posted on 2020-12-27
405 3dSpAn: an interactive software for 3D segmentation and analysis of dendritic spines
Das, N.; Baczynska, E.; Bijata, M.; Ruszczycki, B.; Zeug, A.; Plewczynski, D.; Saha, P. K.; Ponimaskin, E.; Wlodarczyk, J.; Basu, S.
10.1101/864587 — neuroscience — Posted on 2020-12-27
407 UVB mutagenesis differs in NRAS- and BRAF-mutant mouse models of melanoma
Bowman, R. L.; Hennessey, R. C.; Tallman, D. A.; Weiss, T. J.; Crawford, E. R.; Murphy, B. M.; Webb, A.; Zhang, S.; La Perle, K. M. D.; Burd, C. J.; Levine, R. L.; Shain, A. H.; Burd, C. E.
10.1101/778449 — cancer biology — Posted on 2020-12-27
412 NF45/NF90-mediated rDNA transcription provides a novel target for immunosuppressant development
Hsiang-i, T.; Zeng, X.; Liu, L.; Xin, S.; Wu, Y.; Xu, Z.; Liu, G.; Bi, Z.; Su, D.; Yang, M.; Wang, C.; Zhao, J.; Eriksson, J. E.; Deng, W.; Cheng, F.; Chen, H.
10.1101/2020.05.26.116897 — molecular biology — Posted on 2020-12-27
413 Modelling the interaction between Infectious Bursal Disease Virus VP3 polypeptide and dsRNA: identification of key residues for ribonucleoprotein assembly and virus replication
Busnadiego, I.; Martin, M. T.; Ferrero, D. S.; Millan de la Blanca, M. G.; Broto, L.; Diaz-Beneitez, E.; Fuentes, D.; Rodriguez, D.; Verdaguer, N.; Kremer, L.; Rodriguez, J. F.
10.1101/2020.08.06.240028 — microbiology — Posted on 2020-12-27
415 A GenoChemetic strategy for derivatization of the violacein natural product scaffold
Lai, H.-E.; Obled, A. M.; Chee, S. M.; Morgan, R. M.; Lynch, R.; Sharma, S. V.; Moore, S. J.; Polizzi, K. M.; Goss, R. J.; Freemont, P. S.
10.1101/202523 — synthetic biology — Posted on 2020-12-27
418 Mitochondrial mutational spectrum in mammals is sensitive to cellular and organismal longevity by means of A>G transitions.
Mikhaylova, A. G.; Mikhailova, A. A.; Ushakova, K.; Tretyakov, E.; Iurchenko, A.; Zazhytska, M.; Zdobnov, E.; Makeev, V.; Yurov, V.; Tanaka, M.; Gostimskaya, I.; Fleischmann, Z.; Annis, S.; Franco, M.; Wasko, K.; Kunz, W.; Knorre, D.; Mazunin, I.; Nikolaev, S.; Fellay, J.; Reymond, A.; Khrapko, K.; Gunbin, K.; Popadin, K.
10.1101/589168 — genomics — Posted on 2020-12-26
422 X-MOL: large-scale pre-training for molecular understanding and diverse molecular analysis
Xue, D.; Zhang, H.; Xiao, D.; Gong, Y.; Chuai, G.; Sun, Y.; Tian, H.; Wu, H.; Li, Y.; Liu, Q.
10.1101/2020.12.23.424259 — bioinformatics — Posted on 2020-12-26
426 Landscape configuration of an Amazonian island-like ecosystem drives population structure and genetic diversity of a habitat-specialist bird
Ritter, C. D.; Ribas, C. C.; Menger, J.; Borges, S. H.; Bacon, C. D.; Metzger, J. P.; Bates, J.; Cornelius, C.
10.1101/2020.12.25.424395 — ecology — Posted on 2020-12-26
427 A small increase in CHEK1 activity leads to the arrest of the first zygotic division in human
Chen, B.; Guo, J.; Wang, T.; Lee, Q.; Ming, J.; Ding, F.; Li, H.; Zhang, Z.; Li, L.; Cao, Y.; Na, J.
10.1101/2020.12.26.424381 — developmental biology — Posted on 2020-12-26
431 Activation of cGAS/STING pathway upon paramyxovirus infection
Iampietro, M.; Dumont, C.; Mathieu, C.; Spanier, J.; Robert, J.; Charpenay, A.; Dupichaud, S.; Dhondt, K. P.; Aurine, N.; Pelissier, R.; Ferren, M.; Mely, S.; Gerlier, D.; Kalinke, U.; Horvat, B.
10.1101/2020.12.26.424443 — immunology — Posted on 2020-12-26
438 IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.
Laliotis, G. I.; Chavdoula, E.; Paraskevopoulou, M. D.; Kaba, A. D.; La Ferlita, A.; Singh, S.; Anastas, V.; Alaimo, S.; Orlacchio, A.; Nair, K. A.; Taraslia, V.; Vlachos, I.; Capece, M.; Hatzigeorgiou, A.; Palmieri, D. I.; Tsatsanis, C.; Sehgal, L.; Carbone, D. P.; Coppola, V.; Tsichlis, P. N.
10.1101/2020.07.14.195297 — cancer biology — Posted on 2020-12-26
439 The P4-ATPase Drs2 regulates homeostasis of Atg9
Pazos Capell, I.; Puig-Tinto, M.; Cordero, J.; Jimenez-Menendez, N.; Abella Guerra, M.; G. Duran, A.; Adachi-Fernandez, E.; Belmonte, C.; Sabido-Bozo, S.; Chinchilla, A.; Tosi, S.; Nezu, A.; Colombelli, J.; Graham, T.; Yoshimori, T.; Muniz, M.; Hamasaki, M.; Gallego, O.
10.1101/2020.12.25.417865 — cell biology — Posted on 2020-12-26
442 A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions
Liu, B.; Shi, H.; Rangadurai, A.; Nussbaumer, F.; Chu, C.-C.; Erharter, K. A.; Case, D. A.; Kreutz, C.; Al-Hashimi, H. M.
10.1101/2020.12.25.424401 — biochemistry — Posted on 2020-12-26
443 Marine community metabolomes carry fingerprints of phytoplankton community composition
Heal, K. R.; Durham, B.; Boysen, A. K.; Carlson, L. T.; Qin, W.; Ribalet, F.; White, A. E.; Bundy, R. M.; Armbrust, E. V.; Ingalls, A. E.
10.1101/2020.12.22.424086 — ecology — Posted on 2020-12-26
444 Development of novel in vitro human alveolar epithelial cell models to study distal lung biology and disease
Tran, E.; Shi, T.; Li, X.; Chowdhury, A. Y.; Jiang, D.; Liu, Y.; Wang, H.; Yan, C.; Wallace, W. D.; Lu, R.; Ryan, A. L.; Marconett, C. N.; Zhou, B.; Borok, Z.; Offringa, I. A.
10.1101/2020.12.25.424415 — cell biology — Posted on 2020-12-26
445 Human gut Faecalibacterium prausnitzii deploy a highly efficient conserved system to cross-feed on β-mannan-derived oligosaccharides
Lindstad, L. J.; Lo, G.; Leivers, S. A.; Lu, Z.; Michalak, L.; Vasconcelos Pereira, G.; Rohr, A. K.; Martens, E.; McKee, L. S.; Duncan, S.; Westereng, B.; Pope, P. B.; La Rosa, S. L.
10.1101/2020.12.23.424282 — microbiology — Posted on 2020-12-26
448 Time series transcriptomics reveals a BBX32-directed control of dynamic acclimation to high light in mature Arabidopsis leaves
Mullineaux, P. M.; Alvarez-Fernandez, R.; Penfold, C. A.; Galvez-Valdivieso, G.; Exposito-Rodriguez, M.; Stallard, E. J.; Bowden, L.; Moore, J. D.; Mead, A.; Davey, P.; Matthews, J. S.; Beynon, J.; Buchanan-Wollaston, V.; Wild, D. L.; Lawson, T.; Bechtold, U.; Denby, K.
10.1101/2020.12.23.424212 — plant biology — Posted on 2020-12-26
450 A cancer cell-intrinsic GOT2-PPARδ axis suppresses antitumor immunity
Sanford-Crane, H.; Abrego, J.; Oon, C.; Xiao, X.; Nagarajan, S.; Bhattacharyya, S.; Tontonoz, P.; Sherman, M. H.
10.1101/2020.12.25.424393 — cancer biology — Posted on 2020-12-26
451 Pulmonary stromal expansion and intra-alveolar coagulation are primary causes of Covid-19 death
Szekely, L.; Bozoky, B.; Bendek, M.; Ostad, M.; Lavignasse, P.; Haag, L.; Wu, J.; Jing, X.; Gupta, S.; Saccon, E.; Sonnerborg, A.; Cao, Y.; Bjornstedt, M.; Szakos, A.
10.1101/2020.12.23.424172 — pathology — Posted on 2020-12-26
452 Characterization of a RAD51C-Silenced High Grade Serous Ovarian Cancer Model During PARP Inhibitor Resistance Development
Hurley, R. M.; McGehee, C. D.; Nesic, K.; Correia, C.; Weiskittel, T. M.; Kelly, R. L.; Venkatachalam, A.; Hou, X.; Pathoulas, N. M.; Meng, X. W.; Kondrashova, O.; Radke, M. R.; Schneider, P. A.; Flatten, K. S.; Peterson, K. L.; Dobrovic, A.; Lin, K. K.; Harding, T. C.; McNeish, I. A.; Ross, C. A.; Wagner, J. M.; Wakefield, M. J.; Scott, C. L.; Haluska, P.; Wahner Hendrickson, A. E.; Karnitz, L. M.; Swisher, E. M.; Li, H.; Weroha, S. J.; Kaufmann, S. H.
10.1101/2020.12.25.419978 — cancer biology — Posted on 2020-12-26
453 Single-cell characterization of subsolid and solid lesions in the lung adenocarcinoma spectrum
Yanagawa, J.; Tran, L. M.; Fung, E.; Wallace, W. D.; Prosper, A. E.; Fishbein, G. A.; Shea, C.; Hong, R.; Liu, B.; Salehi-Rad, R.; Deng, J. Z.; Gower, A.; Campbell, J. D.; Mazzilli, S. A.; Beane, J.; Kadara, H.; Lenburg, M. E.; Spira, A.; Aberle, D. R.; Krysan, K.; Dubinett, S. M.
10.1101/2020.12.25.424416 — cancer biology — Posted on 2020-12-26
454 Novel multicellular prokaryote discovered next to an underground stream
Mizuno, K.; Maree, M.; Nagamura, T.; Koga, A.; Hirayama, S.; Furukawa, S.; Tanaka, K.; Morikawa, K.
10.1101/2020.12.25.424384 — evolutionary biology — Posted on 2020-12-26
455 The P4-ATPase Drs2 regulates the homeostasis of Atg9
Pazos Capell, I.; Puig-Tinto, M.; Cordero, J.; Jimenez-Menendez, N.; Abella Guerra, M.; G. Duran, A.; Adachi-Fernandez, E.; Belmonte, C.; Sabido-Bozo, S.; Chinchilla, A.; Tosi, S.; Nezu, A.; Colombelli, J.; Graham, T.; Yoshimori, T.; Muniz, M.; Hamasaki, M.; Gallego, O.
10.1101/2020.12.25.417865 — cell biology — Posted on 2020-12-26
458 Lipooligosaccharide, Vag8, and pertussis toxin of Bordetella pertussis cooperatively cause coughing in mice
Hiramatsu, Y.; Suzuki, K.; Nishida, T.; Onoda, N.; Satoh, T.; Akira, S.; Ikawa, M.; Ikeda, H.; Kamei, J.; Derouiche, S.; Tominaga, M.; Horiguchi, Y.
10.1101/2020.12.25.424096 — microbiology — Posted on 2020-12-26
460 Asymbiotic mass production of the arbuscular mycorrhizal fungus Rhizophagus clarus
Tanaka, S.; Hashimoto, K.; Kobayashi, Y.; Yano, K.; Maeda, T.; Kameoka, H.; Ezawa, T.; Saito, K.; Akiyama, K.; Kawaguchi, M.
10.1101/2020.12.25.424379 — microbiology — Posted on 2020-12-26
461 TCR meta-clonotypes for biomarker discovery with tcrdist3: quantification of public, HLA-restricted TCR biomarkers of SARS-CoV-2 infection
Mayer-Blackwell, K.; Schattgen, S.; Cohen-Lavi, L.; Crawford, J. C.; Souquette, A.; Gaevert, J. A.; Hertz, T.; Thomas, P. G.; Bradley, P. H.; Fiore-Gartland, A.
10.1101/2020.12.24.424260 — immunology — Posted on 2020-12-26
467 Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes
Jolly, B.; Rophina, M.; Shamnath, A.; Imran, M.; Bhoyar, R. C.; Divakar, M. K.; Rani, P. R.; Ranjan, G.; Sehgal, P.; Chandrasekhar, P.; Afsar, S.; Lakshmi, J. V.; Surekha, A.; Sivasubbu, S.; Scaria, V.
10.1101/2020.12.24.424332 — bioinformatics — Posted on 2020-12-26
468 Engineered pH-Sensitive Protein G / IgG Interaction
Jha, R. K.; Yankey, A.; Shabazz, K.; Naranjo, L.; Velappan, N.; Bradbury, A. R. M.; Strauss, C. E. M.
10.1101/2020.12.25.424402 — biochemistry — Posted on 2020-12-26
469 MEMS directed evolution of two cytochrome P450 enzymes revealing distinct active-sites for convergent function
Ma, L.; Li, F.; Zhang, X.; Chen, H.; Huang, Q.; Liu, X.; Sun, T.; Fang, B.; Liu, K.; Chen, J.; Yao, L.; Wu, D.; Zhang, W.; Lei, D.; Li, S.
10.1101/2020.12.25.424376 — biochemistry — Posted on 2020-12-26
472 Functional architecture of the synaptic transducers at a central glutamatergic synapse
Brockmann, M. M.; Toulme, E.; Grasskamp, A. T.; Trimbuch, T.; Sudhof, T. C.; Walter, A. M.; Rosenmund, C.
10.1101/2020.12.25.424391 — neuroscience — Posted on 2020-12-25
473 Nutrition or nature: disentangling the complex forces shaping prokaryote pan-genomes
Garza, D. R.; von Meijenfeldt, F. A. B.; van Dijk, B.; Boleij, A.; Huynen, M.; Dutilh, B. E.
10.1101/2020.12.14.422685 — evolutionary biology — Posted on 2020-12-25
474 Multi-Modal Biomarkers of Cerebral Edema in Low Resolution MRI
Tu, D.; Goyal, M. S.; Dworkin, J. D.; Kampondeni, S.; Vidal, L.; Biondo-Savin, E.; Juvvadi, S.; Raghavan, P.; Nicholas, J.; Chetcuti, K.; Clark, K.; Satterthwaite, T. D.; Yushkevich, P.; Davatzikos, C.; Erus, G.; Postels, D. G.; Taylor, T. E.; Small, D. S.; Shinohara, R. T.
10.1101/2020.12.23.424020 — neuroscience — Posted on 2020-12-25
475 Cognitive and neural bases of decision-making causing civilian casualties during intergroup conflict
Han, X.; Zhou, S.; Fahoum, N.; Wu, T.; Gao, T.; Shamay-Tsoory, S.; Gelfand, M. J.; Wu, X.; Han, S.
10.1101/2020.12.04.411280 — neuroscience — Posted on 2020-12-25
476 Chronic stress induces sex-specific functional and morphological alterations in cortico-accumbal and cortico-tegmental pathways
Bittar, T. P.; Pelaez, M. C.; Hernandez Silva, J. C.; Quessy, F.; Lavigne, A.-A.; Morency, D.; Blanchette, L.-J.; Arsenault, E.; Cherasse, Y.; Seigneur, J.; Timofeev, I.; Sephton, C. F.; Proulx, C. D.; Labonte, B.
10.1101/2020.09.22.306860 — neuroscience — Posted on 2020-12-25
478 Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens
Buckley, P.; Ma, R.; Lee, C. H.-J.; Woodhouse, I.; Woo, J.; Tsvetkov, V. O.; Shcherbinin, D. S.; Shugay, M.; Rei, M.; Simmons, A.; Koohy, H.
10.1101/2020.12.25.424183 — immunology — Posted on 2020-12-25
480 Cilium induction triggers differentiation of glioma stem cells
Goranci-Buzhala, G.; Mariappan, A.; Ricci-Vitiani, L.; Josipovic, N.; Pacion, S.; Gottardo, M.; Ptok, J.; Callaini, G. C.; Rajalingam, K.; Dynlacht, B.; Hadian, K.; Papantonis, A.; Pallini, R.; Gopalakrishnan, J.
10.1101/2020.12.23.424140 — cell biology — Posted on 2020-12-25
481 Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating the interleukin-6-Hsp70 axis through inter-organ crosstalk
Clemens, M. M.; Kennon-McGill, S.; Vazquez, J. H.; Stephens, O. W.; Peterson, E. A.; Johann, D. J.; Allard, F. D.; Yee, E. U.; McCullough, S. S.; James, L. P.; Finck, B. N.; McGill, M. R.
10.1101/2020.12.22.423312 — pharmacology and toxicology — Posted on 2020-12-25
482 Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L
Ashhurst, A.; Tang, A.; Fajtova, P.; Yoon, M.; Aggarwal, A.; Stoye, A.; Larance, M.; Beretta, L.; Drelich, A.; Skinner, D.; Li, L.; Meek, T.; McKerrow, J.; Hook, V.; Tseng, C.-T.; Turville, S. G.; Gerwick, W.; O'Donoghue, A.; Payne, R. J.
10.1101/2020.12.23.424111 — biochemistry — Posted on 2020-12-25
484 Segmentation pathway genes in the Asian citrus psyllid, Diaphorina citri
Miller, S.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.12.24.424320 — genomics — Posted on 2020-12-25
485 Patterns of within-host genetic diversity in SARS-CoV-2
Tonkin-Hill, G.; Martincorena, I.; Amato, R.; Lawson, A. R. J.; Gerstung, M.; Johnston, I.; Jackson, D. K.; Park, N. R.; Lensing, S. V.; Quail, M. A.; Goncalves, S.; Ariani, C.; Chapman, M. S.; Hamilton, W. L.; Meredith, L. W.; Hall, G.; Jahun, A. S.; Chaudhry, Y.; Hosmillo, M.; Pinckert, M. L.; Georgana, I.; Yakovleva, A.; Caller, L. G.; Caddy, S. L.; Feltwell, T.; Khokhar, F. A.; Houldcroft, C. J.; Curran, M. D.; Parmar, S.; The COVID-19 Genomics UK (COG-UK) Consortium, ; Alderton, A.; Nelson, R.; Harrison, E.; Sillitoe, J.; Bentley, S. D.; Barrett, J. C.; Torok, M. E.; Goodfellow, I. G.; L
10.1101/2020.12.23.424229 — genomics — Posted on 2020-12-25
488 Role of hypothalamic MAPK/ERK signaling in diabetes remission induced by the central action of fibroblast growth factor 1
Brown, J. M.; Bentsen, M. A.; Rausch, D. M.; Phan, B. A.; Wieck, D.; Wasanwala, H.; Matsen, M. E.; Richardson, N.; Zhao, X.; Zhai, P.; Secher, A.; Morton, G. J.; Pers, T. H.; Schwartz, M. W.; Scarlett, J. M.
10.1101/2020.12.24.424313 — neuroscience — Posted on 2020-12-25
489 The IRE1 Inhibitor KIRA6 Curtails The Inflammatory Trait Of Immunogenic Anticancer Treatments By Targeting HSP60 Independent Of IRE1
Rufo, N.; Korovesis, D.; van Eygen, S.; Derua, R.; Garg, A. D.; Finotello, F.; Vara Perez, M.; Rozanc, J.; Dewaele, M.; de Witte, P. A.; Alexopoulos, L.; Janssens, S.; Sinkkonen, L.; Sauter, T.; Verhelst, S. H. L.; Agostinis, P.
10.1101/2020.12.24.424330 — cancer biology — Posted on 2020-12-25
491 Exploring epitope and functional diversity of anti-SARS-CoV2 antibodies using AI-based methods
Dumet, C.; Jullian, Y.; Musnier, A.; Riviere, P.; Poirier, N.; Watier, H.; Bourquard, T.; Poupon, A.
10.1101/2020.12.23.424199 — bioinformatics — Posted on 2020-12-24
493 Structural insights into the recognition of histone H3Q5 serotonylation by WDR5
Zhao, J.; Chen, W.; Zhang, Y.; Yang, F.; Shen, N.; Zhang, X.; Mo, X.; Zang, J.
10.1101/2020.12.24.424296 — biochemistry — Posted on 2020-12-25
495 Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm
Nomaru, H.; Liu, Y.; De Bono, C.; Righelli, D.; Cirino, A.; Wang, W.; Racedo, S. E.; Dantas, A.; Cai, C.; Angelini, C.; Christiaen, L.; Kelly, R.; Baldini, A.; Zheng, D.; Morrow, B. E.
10.1101/2020.12.24.424342 — developmental biology — Posted on 2020-12-24
498 Activation of the type 3 secretion system of enteropathogenic E. coli leads to reprogrammingof its lipid metabolism
Zacharia, A.; Pal, R. R.; Katsowich, N.; Mannully, C. T.; Alfandary, S.; Serruya, R.; Baidya, A.; Ben-Yehuda, S.; Rosenshine, I.; Moussaieff, A.
10.1101/2020.12.17.423234 — microbiology — Posted on 2020-12-24
499 Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro
Varghese, F. S.; van Woudenbergh, E.; Overheul, G. J.; Eleveld, M. J.; Kurver, L.; van Heerbeek, N.; van Laarhoven, A.; Miesen, P.; den Hartog, G.; de Jonge, M. I.; van Rij, R. P.
10.1101/2020.12.23.424189 — microbiology — Posted on 2020-12-24
501 Sustained antibody response to ZIKV infection induced by NS1 protein is accompanied by the progressive appearance of autoreactive antibodies and cross-reactive B cell clones.
Cavazzoni, C. B.; Bozza, V. B.; Tostes, L.; Maia, B.; Mesin, L.; Schiepers, A.; Ersching, J.; Neris, R. L.; Conde, J. N.; Coleho, D. R.; Conde, L.; Paula-Neto, H. A.; Lima, T. M.; Alvim, R. G. F.; Castilho, L. R.; Mohana-Borges, R.; Assuncao-Miranda, I.; Nobrega, A.; Victora, G. D.; Vale, A. M.
10.1101/2020.12.24.423863 — immunology — Posted on 2020-12-24
502 Molecular topography of an entire nervous system
Taylor, S. R.; Santpere, G.; Weinreb, A.; Barrett, A.; Reilly, M. B.; Xu, C.; Varol, E.; Oikonomou, P.; Glenwinkel, L.; McWhirter, R.; Poff, A.; Basavaraju, M.; Rafi, I.; Yemini, E.; Cook, S. J.; Abrams, A.; Vidal, B.; Cros, C.; Tavazoie, S.; Sestan, N.; Hammarlund, M.; Hobert, O.; Miller, D. M.
10.1101/2020.12.15.422897 — neuroscience — Posted on 2020-12-24
503 Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
Raghunandan, A.; Ladron-de-Guevara, A.; Tithof, J.; Mestre, H.; Nedergaard, M.; Thomas, J. H.; Kelley, D. H.
10.1101/2020.11.09.374512 — neuroscience — Posted on 2020-12-24
504 Place cells in head-fixed mice navigating a floating real-world environment
Go, M. A.; Rogers, J.; Gava, G. P.; Davey, C.; Prado, S.; Liu, Y.; Schultz, S. R.
10.1101/2020.10.18.344184 — neuroscience — Posted on 2020-12-24
506 Conductance-Based Structural Brain Connectivity in Aging and Dementia
Frau-Pascual, A.; Augustinak, J.; Varadarajan, D.; Yendiki, A.; Salat, D. H.; Fischl, B.; Aganj, I.
10.1101/2020.09.15.298331 — neuroscience — Posted on 2020-12-25
508 Cell-type apoptosis in lung during SARS-CoV-2 infection
Liu, Y.; Garron, T. M.; Chang, Q.; Su, Z.; Zhou, C.; Gong, E. C.; Zheng, J.; Yin, W.; Ksiazek, T.; Brasel, T.; Jin, Y.; Boor, P.; Comer, J. E.; Gong, B.
10.1101/2020.12.23.424254 — pathology — Posted on 2020-12-24
509 Authentication of In Situ Measurements for Thoracic Aortic Aneurysms in Mice
Ohno-Urabe, S.; Kukida, M.; Franklin, M. K.; Lu, H. S.; Daugherty, A.; Sawada, H.
10.1101/2020.12.24.424013 — pathology — Posted on 2020-12-24
510 USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer
Rossi, F. A.; Enrique Steinberg, J. H.; Calvo Roitberg, E. H.; Joshi, M.; Pandey, A.; Abba, M.; Dufrusine, B.; Buglioni, S.; De Laurenzi, V.; Sala, G.; Lattanzio, R.; Espinosa, J. M.; Rossi, M.
10.1101/2020.07.01.181883 — cancer biology — Posted on 2020-12-24
512 LigEGFR: Spatial graph embedding and molecular descriptors assisted bioactivity prediction of ligand molecules for epidermal growth factor receptor on a cell line-based dataset
Virakarin, P.; Saengnil, N.; Boonyarit, B.; Kinchagawat, J.; Laotaew, R.; Saeteng, T.; Nilsu, T.; Suvannang, N.; Rungrotmongkol, T.; Nutanong, S.
10.1101/2020.12.24.423424 — bioinformatics — Posted on 2020-12-24
513 F-domain valency determines outcome of signaling through the angiopoietin pathway
Zhao, Y. T.; Fallas, J. A.; Saini, S.; Ueda, G.; Somasundaram, L.; Zhou, Z.; Xavier, I.; Ehnes, D.; Xu, C.; Carter, L.; Wrenn, S.; Mathieu, J.; Sellers, D. L.; Baker, D.; Ruohola-Baker, H.
10.1101/2020.09.19.304188 — biochemistry — Posted on 2020-12-24
514 SHMT1-RNA interaction dynamically regulates serine and glycine concentration in cells
Monti, M.; Guiducci, G.; Paone, A.; Rinaldo, S.; Giardina, G.; Cutruzzola, F.; Tartaglia, G.
10.1101/2020.12.24.424304 — biochemistry — Posted on 2020-12-24
517 Chitin biosynthesis genes in Diaphorina citri, Asian citrus psyllid
Miller, S.; Shippy, T.; Tamayo, B.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.09.22.309211 — genomics — Posted on 2020-12-24
518 Real-time monitoring epidemic trends and key mutations in SARS-CoV-2 evolution by an automated tool
Xi, B.; Jiang, D.; Li, S.; Lon, J. R.; Bai, Y.; Lin, S.; Hu, M.; Meng, Y.; Qu, Y.; Huang, Y.; Liu, W.; Du, H.
10.1101/2020.12.24.424271 — genomics — Posted on 2020-12-24
521 Genomic evidence for global ocean plankton biogeography shaped by large-scale current systems
Richter, D. J.; Watteaux, R.; Vannier, T.; Leconte, J.; Fremont, P.; Reygondeau, G.; Maillet, N.; Henry, N.; Benoit, G.; Da Silva, O.; Delmont, T. O.; Fernandez-Guerra, A.; Suweis, S.; Narci, R.; Berney, C.; Eveillard, D.; Gavory, F.; Guidi, L.; Labadie, K.; Mahieu, E.; Poulain, J.; Romac, S.; Roux, S.; Dimier, C.; Kandels, S.; Picheral, M.; Searson, S.; Tara Oceans Coordinators, ; Pesant, S.; Aury, J.-M.; Brum, J. R.; Lemaitre, C.; Pelletier, E.; Bork, P.; Sunagawa, S.; Lombard, F.; Karp-Boss, L.; Bowler, C.; Sullivan, M. B.; Karsenti, E.; Mariadassou, M.; Probert, I.; Peterlongo, P.;
10.1101/867739 — ecology — Posted on 2020-12-24
522 Global drivers of eukaryotic plankton biogeography in the sunlit ocean
Sommeria-Klein, G.; Watteaux, R.; Iudicone, D.; Bowler, C.; Morlon, H.
10.1101/2020.09.08.287524 — ecology — Posted on 2020-12-24
524 Asymmetric robustness in the feedback control of the retinoic acid network response to environmental disturbances
Parihar, M.; Bendelac-Kapon, L.; Gur, M.; Belorkar, A.; Achanta, S.; Kinberg, K.; Vadigepalli, R.; Fainsod, A.
10.1101/2020.07.15.203794 — developmental biology — Posted on 2020-12-24
526 Detection and molecular characterisation of SARS-CoV-2 in farmed mink (Neovision vision) in Poland
Rabalski, L.; Kosinski, M.; Smura, T.; Aaltonen, K.; Kant, R.; Sironen, T.; Szewczyk, B.; Grzybek, M.
10.1101/2020.12.24.422670 — microbiology — Posted on 2020-12-24
527 Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Jeffreys, L.; Pennington, S. H.; Duggan, J.; Breen, A.; Jinks, J.; Ardrey, A.; Donnellan, S.; Patterson, E. I.; Hughes, G. I.; Hong, W. D.; O'Neill, P. M.; Aljayyoussi, G.; Owen, A.; Ward, S. A.; Biagini, G.
10.1101/2020.12.23.424232 — microbiology — Posted on 2020-12-24
530 An open source platform for presenting dynamic visual stimuli
Swanson, K.; White, S. R.; Preston, M. W.; Wilson, J.; Mitchell, M.; Laubach, M.
10.1101/2020.12.24.424344 — neuroscience — Posted on 2020-12-24
532 Cortical stroke produces secondary injury and long-lasting gliosis in the ipsilateral thalamus
Kim, G. S.; Stephenson, J. M.; Abdullah, M. A.; Wu, T.; Goss, M. G.; Min, J.-W.; Li, J.; Liu, F.; Marrelli, S. P.
10.1101/2020.12.24.424329 — neuroscience — Posted on 2020-12-24
536 Cytoplasmic and nuclear Sw-5b synergistically induce plant immune responses to inhibit different viral infection steps
Chen, H.; Qian, X.; Chen, X.; Yang, T.; Feng, M.; Chen, J.; Cheng, R.; Hong, H.; Zheng, Y.; Mei, Y.; Shen, D.; Xu, Y.; Zhu, M.; Ding, X. S.; Tao, X.
10.1101/2020.12.24.424293 — plant biology — Posted on 2020-12-24
539 MG53 is not a critical regulator of insulin signaling pathway in skeletal muscle
Delerive, P.; Philouze, C.; Turban, S.; Cremers, B.; Caliez, A.; Lamarche, G.; Bernard, C.; Provost, N.
10.1101/2020.12.24.424288 — cell biology — Posted on 2020-12-24
540 Automated Biomarker Candidate Discovery in Imaging Mass Spectrometry Data Through Spatially Localized Shapley Additive Explanations
Tideman, L. E. M.; Migas, L. G.; Djambazova, K. V.; Patterson, N. H.; Caprioli, R. M.; Spraggins, J. M.; Van de Plas, R.
10.1101/2020.12.23.424201 — bioinformatics — Posted on 2020-12-24
554 Genome-wide Copy Number Variations in a Large Cohort of Bantu African Children
Yilmaz, F.; Null, M.; Astling, D. P.; Yu, H.-C.; Cole, J. B.; Santorico, S. A.; Hallgrimsson, B.; Manyama, M.; Spritz, R. A.; Hendricks, A. E.; Shaikh, T. H.
10.1101/2020.12.24.424207 — genomics — Posted on 2020-12-24
555 Reconstructing the human genetic history of mainland Southeast Asia: insights from genome-wide data from Thailand and Laos
Kutanan, W.; Liu, D.; Kampuansai, J.; Srikummool, M.; Srithawong, S.; Shoocongdej, R.; Sangkhano, S.; Ruangchai, S.; Pittayaporn, P.; Arias, L.; Stoneking, M.
10.1101/2020.12.24.424294 — genomics — Posted on 2020-12-24
556 The gap-free rice genomes provide insights for centromere structure and function exploration and graph-based pan-genome construction
Song, J.-M.; Xie, W.-Z.; Wang, S.; Guo, Y.-X.; Poland, J.; Koo, D.-H.; Kudrna, D.; Long, E.; Huang, Y.; Feng, J.-W.; Zhang, W.; Lee, S.; Talag, J.; Zhou, R.; Zhu, X.-T.; Yuan, D.; Udall, J.; Xie, W.; Wing, R. A.; Zhang, Q.; Zhang, J.; Chen, L.-L.
10.1101/2020.12.24.424073 — genomics — Posted on 2020-12-24
557 Mapping the probability of forest snowdisturbances in Finland
Suvanto, S.; Lehtonen, A.; Nevalainen, S.; Lehtonen, I.; Viiri, H.; Strandström, M.; Peltoniemi, M.
10.1101/2020.12.23.424139 — ecology — Posted on 2020-12-24
558 Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis
Xiao, F.; Lam, N.; Wang, P.; Li, S.; Canseco, D.; Kimura, W.; Luo, X.; Nguyen, N. U. N.; El Helaly, W.; Singh, R.; Sadayappan, S.; Kanchwala, M.; Xing, C.; Hajjar, R.; Hill, J.; Sadek, H.
10.1101/2020.12.24.424022 — cell biology — Posted on 2020-12-24
563 Periscope Proteins are variable length regulators of bacterial cell surface interactions
Whelan, F.; Lafita, A.; Gilburt, J.; Degut, C.; Griffiths, S. C.; Jenkins, H. T.; St John, A. N.; Paci, E.; Moir, J. W. B.; Plevin, M. J.; Baumann, C. G.; Bateman, A.; Potts, J. R.
10.1101/2020.12.24.424174 — microbiology — Posted on 2020-12-24
569 Three neurotransmitters regulate diverse inhibitory and excitatory Parvalbumin interneuron circuits in the dorsal horn
Gradwell, M. A.; Boyle, K. A.; Browne, T. J.; Dickie, A. C.; Bell, A. M.; Leonardo, J.; Peralta Reyes, F. S.; Smith, K. M.; Callister, R. J.; Dayas, C. V.; Hughes, D. I.; Graham, B. A.
10.1101/2020.12.23.424233 — neuroscience — Posted on 2020-12-24
571 A hypothesis for theta rhythm frequency control in CA1 microcircuits
Skinner, F.; Rich, S.; Lunyov, A.; Lefebvre, J.; Chatzikalymniou, A.
10.1101/2020.12.23.424154 — neuroscience — Posted on 2020-12-24
572 In vivo visualization of pig vagus nerve 'vagotopy' using ultrasound
Settell, M. L.; Kasole, M.; Skubal, A. C.; Knudsen, B. E.; Nicolai, E. N.; Huang, C.; Zhou, C.; Trevathan, J. K.; Pelot, N. A.; Grill, W. M.; Upadhye, A.; Kolluru, C.; Shoffstall, A. J.; Williams, J. C.; Suminski, A. J.; Chen, S.; Ludwig, K. A.
10.1101/2020.12.24.424256 — neuroscience — Posted on 2020-12-24
576 Universal salt iodization contributes to health equity: socio-economic status does not affect iodine status in children in Macedonia
Milevska-Kostova, N.; Karanfilski, B.; Miladinova, D.; Kuzmanovska, S.; Chuleva, B.; Majstorov, V.; Ittermann, T.; Volzke, H.
10.1101/2020.12.24.424286 — physiology — Posted on 2020-12-24
579 Mechanical frustration of phase separation in the cell nucleus by chromatin
Zhang, Y.; Lee, D. S. W.; Meir, Y.; Brangwynne, C. P.; Wingreen, N. S.
10.1101/2020.12.24.424222 — biophysics — Posted on 2020-12-24
583 LigEGFR: Spatial graph embedding and molecular descriptors assisted bioactivity prediction of ligand molecules for epidermal growth factor receptor on a cell line-based dataset
Virakarin, P.; Saengnil, N.; Boonyarit, B.; Kinchagawat, J.; Laotaew, R.; Saeteng, T.; Nilsu, T.; Suvannang, N.; Rungrotmongkol, T.; Nutanong, S.
10.1101/2020.12.24.423424 — bioinformatics — Posted on 2020-12-24
586 On-chip perivascular niche with patient-derived glioma cells
Gerigk, M.; Bulstrode, H.; Shi, H. H.; Toenisen, F.; Cerutti, C.; Morrison, G.; David, R.; Huang, Y. Y. S.
10.1101/2020.12.23.424179 — bioengineering — Posted on 2020-12-24
588 Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8
Shin, G.; Greer, S. U.; Hopmans, E.; Grimes, S. M.; Lee, H.; Zhao, L.; Miotke, L.; Suarez, C.; Almeda, A. F.; Haraldsdottir, S.; Ji, H. P.
10.1101/2020.12.23.422767 — genomics — Posted on 2020-12-24
591 Genome evolution in a putatively asexual wasp
Tvedte, E. S.; Ward, A. C.; Trendle, B.; Forbes, A. A.; Logsdon, J. M.
10.1101/2020.12.23.424202 — evolutionary biology — Posted on 2020-12-24
593 Coalescent-based species delimitation meets deep learning: Insights from a highly fragmented cactus system
Perez, M. F.; Bonatelli, I. A.; Romeiro-Brito, M.; Franco, F. F.; Taylor, N. P.; Zappi, D. C.; Moraes, E. M.
10.1101/2020.12.23.424219 — evolutionary biology — Posted on 2020-12-24
597 PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure
Taylor, R. A.; Xiao, S.; Carias, A. M.; McRaven, M. D.; Thakkar, D. N.; Arainga, M.; Allen, E. J.; Rogers, K. A.; Kumarapperuma, S. C.; Gong, S.; Fought, A. J.; Anderson, M. R.; Thomas, Y.; Schneider, J. R.; Goins, B.; Fox, P.; Villinger, F. J.; Ruprecht, R. M.; Hope, T. J.
10.1101/2020.12.23.423870 — cell biology — Posted on 2020-12-24
598 Transgelin: A New Gene Involved in LDL Endocytosis Identified by a Genome-wide CRISPR-Cas9 Screen
Lucero, D.; Dikilitas, O.; Mendelson, M. M.; Islam, P.; Neufeld, E. B.; Bansal, A. T.; Freeman, L. A.; Vaisman, B.; Tang, J.; Combs, C. A.; Li, Y.; Voros, S.; Kullo, I. J.; Remaley, A. T.
10.1101/2020.12.23.424170 — cell biology — Posted on 2020-12-24
602 4sUDRB-sequencing for genome-wide transcription bursting quantification in breast cancer cells
Beckman, W. F.; Lermo Jimenez, M. A.; Moerland, P. D.; Westerhoff, H. V.; Verschure, P. J.
10.1101/2020.12.23.424175 — molecular biology — Posted on 2020-12-24
603 Functional Characterization of a Lassa Virus Fusion Inhibitors Adaptive Mutant
Guo, J.; Zhang, G.; Liu, Y.; Cao, J.; Zhang, M.; Lan, X.; Zhang, Y.; Liu, C.; Xiao, G.; Wang, W.
10.1101/2020.12.23.424274 — microbiology — Posted on 2020-12-24
605 Neoantigen-driven B cell and CD4+ T follicular helper cell collaboration promotes robust anti-tumor CD8+ T cell responses
Cui, C.; Wang, J.; Chen, P.-M.; Connolly, K. A.; Damo, M.; Fagerberg, E.; Chen, S.; Eisenbarth, S. C.; Zhao, H.; Craft, J.; Joshi, N. S.
10.1101/2020.12.23.424168 — immunology — Posted on 2020-12-24
608 MaPPeRTrac: A Massively Parallel, Portable, and Reproducible Tractography Pipeline
Moon, J.; Bremer, P.-T.; Mukherjee, P.; Markowitz, A. J.; Palacios, E. M.; Rodriguez, A.; Xiao, Y.; Manley, G. T.; Madduri, R.
10.1101/2020.12.23.424191 — neuroscience — Posted on 2020-12-24
609 Overexpression of human alpha-synuclein leads to dysregulated microbiome and metabolites with ageing in a rat model of Parkinson disease
Singh, Y.; Trautwein, C.; Romani, J.; Salker, M.; Neckel, P. H.; Fraccaroli, I.; Abeditashi, M.; Woerner, N.; Adamard, J.; Dhariwal, A.; Dueholm, M. S.; Schaefer, K.-H.; Lang, F.; Otzen, D. E.; Lashuel, H.; Riess, O.; Casadei, N.
10.1101/2020.12.23.424226 — neuroscience — Posted on 2020-12-24
612 Time Perception through the Processing of Verb Tenses: An ERP study regarding Mental Time Travel
Papageorgiou, C.; Giannopoulos, A. E.; Fokas, A. S.; Thompson, P. M.; Kapsalis, N. C.; Papageorgiou, P.; Stachtea, X.; Capsalis, C. N.
10.1101/2020.12.23.424164 — neuroscience — Posted on 2020-12-24
613 Prenatal THC does not affect female mesolimbic dopaminergic system in preadolescent rats
Traccis, F.; Serra, V.; Sagheddu, C.; Congiu, M.; Saba, P.; Giua, G.; Devoto, P.; Frau, R.; Cheer, J. F.; Melis, M.
10.1101/2020.12.23.424157 — neuroscience — Posted on 2020-12-24
616 The mechanism underlying transient weakness in myotonia congenita
Rich, M. M.; Myers, J. H.; Denman, K.; DuPont, C.; Hawash, A. A.; Novak, K. R.; Koesters, A.; Grabner, M.; Dayal, A.; Voss, A. A.
10.1101/2020.12.23.424129 — physiology — Posted on 2020-12-24
617 Translatome-based classification reveals a dual metabolic dependency of a new tumor subtype of pancreatic cancer.
Shin, S.; Nicolle, R.; Jean, C.; Samain, R.; Ayadi, M.; Raffenne, J.; Brunel, A.; Solorzano, J.; Neuzillet, C.; Joffre, C.; Rocchi, S.; Iovanna, J.; Dusetti, N. J.; Larsson, O.; Pyronnet, S.; Bousquet, C.; Martineau, Y.
10.1101/2020.12.23.424227 — cancer biology — Posted on 2020-12-24
618 Functional architecture of the pancreatic islets: First responder cells drive the first-phase response
Kravets, V.; Dwulet, J. M.; Schleicher, W. E.; Hodson, D. J.; Davis, A. M.; Piscopio, R. A.; Sticco-Ivins, M.; Benninger, R. K.
10.1101/2020.12.22.424082 — biophysics — Posted on 2020-12-24
620 Massive colonization of protein-coding exons by selfish genetic elements in Paramecium germline genomes
Sellis, D.; Guerin, F.; Arnaiz, O.; Pett, W.; Lerat, E.; Boggetto, N.; Krenek, S.; Berendonk, T.; Couloux, A.; Aury, J.-M.; Labadie, K.; Malinski, S.; Meyer, E.; Sperling, L.; Duret, L.; Duharcourt, S.
10.1101/2020.12.23.424184 — genomics — Posted on 2020-12-24
623 cDC1 and interferons promote spontaneous CD4+ and CD8+ T cell protective responses to breast cancer
Mattiuz, R.; Brousse, C.; Ambrosini, M.; Cancel, J.-C.; Bessou, G.; Mussard, J.; Sanlaville, A.; Caux, C.; Bendriss-Vermare, N.; Valladeau-Guilemond, J.; Dalod, M.; Crozat, K.
10.1101/2020.12.23.424092 — immunology — Posted on 2020-12-24
624 Single cell analysis of blood mononuclear cells stimulated through CD3 and CD28 shows collateral activation of B and NK cells and demise of monocytes
Lawlor, N. T.; Nehar-Belaid, D.; Grassmann, J.; Stoeckius, M.; Smibert, P.; Stitzel, M. L.; Pascual, V.; Banchereau, J.; Williams, A.; Ucar, D.
10.1101/2020.12.23.424147 — immunology — Posted on 2020-12-24
625 Multiple Mechanisms of HIV-1 resistance to PGT135 in Chinese Subtype B' Slow Progressor
Sun, S.; Zou, S.; Hu, Y.; Liu, Y.; Ren, L.; Hao, Y.; Hu, X.; Ruan, Y.; Ma, L.; Shao, Y.; Hong, K.
10.1101/2020.12.22.424087 — immunology — Posted on 2020-12-24
629 Variation and mechanisms of life history evolution in insular dwarfism as revealed by a natural experiment
Hayashi, S.; Kubo, M. O.; Sanchez-Villagra, M. R.; Taruno, H.; Izawa, M.; Shiroma, T.; Nakano, T.; Fujita, M.
10.1101/2020.12.23.424186 — evolutionary biology — Posted on 2020-12-24
630 Ecm29-dependent proteasome localization regulates cytoskeleton remodeling at the immune synapse
Ibanez-Vega, J.; Del Valle Batalla, F.; Saez, J. J.; Diaz, J.; Soza, A.; Yuseff, M.-I.
10.1101/2020.12.23.424144 — cell biology — Posted on 2020-12-24
631 The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines pathogenicity
Gravdal, A.; Xiao, X.; Cnop, M.; El Jellas, K.; Njolstad, P. R.; Lowe, M. E.; Johansson, B. B.; Molven, A.; Fjeld, K.
10.1101/2020.12.23.424204 — cell biology — Posted on 2020-12-24
632 C53 interacting with UFM1-protein ligase 1 regulates microtubule nucleation in response to ER stress
Klebanovych, A.; Vinopal, S.; Draberova, E.; Sladkova, V.; Sulimenko, T.; Sulimenko, V.; Vosecka, V.; Macurek, L.; Legido, A.; Draber, P.
10.1101/2020.12.23.424116 — cell biology — Posted on 2020-12-24
633 Multifractal roots of suprapostural dexterity
Kelty-Stephen, D. G.; Lee, I.-C.; Carver, N. S.; Newell, K. M.; Mangalam, M.
10.1101/2020.07.17.209502 — neuroscience — Posted on 2020-12-24
637 Dynamic Methylome Modification associated with mutational signatures in ageing and etiology of disease
Kumar, G.; Krishnasamy, K.; Pasha, N.; Nagarajan, N.; Mam, B.; Kishinani, M.; Vohra, V.; Jain, R.; Morawala Patell, V.
10.1101/2020.12.22.423778 — genomics — Posted on 2020-12-24
638 Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung
Liu, H.; Xu, W.; Bruno, V. M.; Phan, Q. T.; Solis, N. V.; Woolford, C. A.; Ehrlich, R.; Shetty, A. C.; McCracken, C.; Lin, J.; Mitchell, A. P.; Filler, S. G.
10.1101/2020.12.23.424128 — microbiology — Posted on 2020-12-23
642 Are indigenous territories and community-managed areas effective natural climate solutions? A neotropical analysis using matching methods and geographic discontinuity designs.
Alejo, C.; Meyer, C.; Walker, W. S.; Gorelik, S. R.; Josse, C.; Aragon-Osejo, J. L.; Rios, S.; Augusto, C.; Llanos, A.; Coomes, O. T.; Potvin, C.
10.1101/2020.12.23.424126 — ecology — Posted on 2020-12-23
644 Left Hippocampus to Anterior Cingulate Cortex Connectivity Correlates with Worse Recent Verbal Memory in Pornography Addicted Juveniles
Prawiroharjo, P.; Edison, M.D., R. E.; Ellydar, H.; Pratama, M.D., P.; Suaidy, S. E. I.; Amani, N. Z.; Carissima, D.; Hatta, M.D., G. F.
10.1101/2020.12.23.424123 — neuroscience — Posted on 2020-12-23
648 NgAgo DNA endonuclease activity enhances homologous recombination in E. coli
Lee, K. Z.; Mechikoff, M. A.; Kikla, A.; Liu, A.; Pandolfi, P.; Fitzgerald, K.; Gimble, F. S.; Solomon, K.
10.1101/597237 — molecular biology — Posted on 2020-12-23
651 Daily electrical activity in the master circadian clock of a diurnal mammal
Bano Otalora, B.; Moye, M. J.; Brown, T. M.; Lucas, R. J.; Diekman, C. O.; Belle, M. D. C.
10.1101/2020.12.23.424225 — neuroscience — Posted on 2020-12-23
653 Variability within rare cell states enables multiple paths towards drug resistance
Emert, B.; Cote, C.; Torre, E. A.; Dardani, I. P.; Jiang, C.; Jain, N.; Shaffer, S. M.; Raj, A.
10.1101/2020.03.18.996660 — systems biology — Posted on 2020-12-23
654 A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data
Douglass, E. F.; Allaway, R. J.; Szalai, B.; Wang, W.; Tian, T.; Fernandez-Torras, A.; Realubit, R.; Karan, C.; Zheng, S.; Pessia, A.; Tanoli, Z.; Jafari, M.; Wan, F.; Li, S.; Xiong, Y.; Duran-Frigola, M.; Bertoni, M.; Badia-i-Mompel, P.; Mateo, L.; Guitart-Pla, O.; Chung, V.; DREAM CTD-squared Pancancer Drug Activity Challenge Consortium, ; Tang, J.; Zeng, J.; Aloy, P.; Saez-Rodriguez, J.; Guinney, J.; Gerhard, D. S.; Califano, A.
10.1101/2020.12.21.423514 — cancer biology — Posted on 2020-12-23
656 The costs of competition: high social status males experience accelerated epigenetic aging in wild baboons
Anderson, J. A.; Johnston, R. A.; Lea, A. J.; Campos, F. A.; Voyles, T. N.; Akinyi, M. Y.; Alberts, S. C.; Archie, E. A.; Tung, J.
10.1101/2020.02.22.961052 — genomics — Posted on 2020-12-23
657 A new method to accurately identify single nucleotide variants using small FFPE breast samples.
Fortunato, A.; Mallo Adan, D.; Rupp, S. M.; King, L.; Hardman, T.; Lo, J.; Hall, A.; Marks, J. R.; Hwang, E. S.; Maley, C. C.
10.1101/2020.10.22.350983 — genomics — Posted on 2020-12-23
658 Knockout of myoc reveals the role of myocilin in zebrafish sex determination associated with Wnt signalling downregulation
Atienzar-Aroca, R.; Aroca-Aguilar, J.-D.; Alexandre-Moreno, S.; Ferre-Fernández, J.-J.; Juan-Manuel Bonet-Fernández, J.-M.; Cabañero-Varela, M.-J.; Escribano, J.
10.1101/2020.11.17.380147 — genetics — Posted on 2020-12-23
662 The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles
Gomes Pereira, S.; Sousa, A. L.; Nabais, C.; Paixao, T.; Holmes, A. J.; Schorb, M.; Goshima, G.; Tranfield, E. M.; Becker, J. D.; Bettencourt-Dias, M.
10.1101/2020.12.21.423647 — cell biology — Posted on 2020-12-23
665 Striatal BOLD and midfrontal theta power express motivation for action
Algermissen, J.; Swart, J. C.; Scheeringa, R.; Cools, R.; den Ouden, H. E. M.
10.1101/2020.09.11.292870 — neuroscience — Posted on 2020-12-23
668 Inclusion of maintenance energy improves the intracellular flux predictions of CHO
Szeliova, D.; Stor, J.; Thiel, I.; Weinguny, M.; Hanscho, M.; Lhota, G.; Borth, N.; Zanghellini, J.; Ruckerbauer, D. E.; Rocha, I.
10.1101/2020.12.21.423738 — systems biology — Posted on 2020-12-23
669 GNS561, a new autophagy inhibitor active against cancer stem cells in hepatocellular carcinoma and hepatic metastasis from colorectal cancer
Brun, S.; Pascussi, J.-M.; Gifu, E. P.; Bestion, E.; Macek-Jilkova, Z.; Wang, G.; Bassissi, F.; Mezouar, S.; Courcamberck, J.; Merle, P.; Decaens, T.; Pannequin, J.; Halfon, P.; Caron de Fromentel, C.
10.1101/2020.12.21.423741 — cancer biology — Posted on 2020-12-23
675 CaMKII binds both substrates and effectors at the active site
Ozden, C.; Sloutsky, R.; Santos, N.; Agnello, E.; Gaubitz, C.; Esposito, E. A.; Lapinskas, E.; Foster, J.; Kelch, B. A.; Garman, S. C.; Hayashi, Y.; Stratton, M.
10.1101/2020.10.25.354241 — biochemistry — Posted on 2020-12-23
678 Differential Expression of NPAS4 in the Dorsolateral Prefrontal Cortex Following Acute Opioid Intoxication
Sosnowski, D. W.; Jaffe, A. E.; Tao, R.; Deep-Soboslay, A.; Kleinman, J. E.; Hyde, T. M.; Shu, C.; Sabunciyan, S.; Maher, B. S.
10.1101/2020.12.23.424239 — genomics — Posted on 2020-12-23
682 Genetic architecture of transmission stage production and virulence in schistosome parasites
Le Clech, W.; Chevalier, F. D.; McDew-White, M.; Menon, V.; Arya, G.-A.; Anderson, T. J. C.
10.1101/2020.12.23.424224 — genetics — Posted on 2020-12-23
686 Analysis of the intrinsic chromatin binding property of HIV-1 integrase and its regulation by LEDGF/p75 using human chromosomes spreads
Lapaillerie, D.; Mauro, E.; Lelandais, B.; Ferran, G.; Kuschner, N.; Calmels, C.; Metifiot, M.; Rooryck, C.; Ruff, M.; Zimmer, C.; Paul, L.; Toutain, J.; Parissi, V.
10.1101/2020.12.23.424107 — microbiology — Posted on 2020-12-23
687 Processive Dynamics of the Usher Assembly Platform During Uropathogenic Escherichia coli P Pilus Biogenesis
Du, M.; Yuan, Z.; Werneburg, G. T.; Henderson, N. S.; Chauhan, H.; Kovach, A.; Zhao, G.; Johl, J.; Li, H.; Thanassi, D. G.
10.1101/2020.12.23.424195 — microbiology — Posted on 2020-12-23
689 The schizophrenia-associated variant in SLC39A8 alters N-glycosylation in the mouse brain
Mealer, R. G.; Williams, S. E.; Noel, M.; Yang, B.; D'Souza, A.; Nakata, T.; Graham, D. B.; Creasey, E. A.; Cetinbas, M.; Sadreyev, R.; Scolnick, E. M.; Woo, C. M.; Smoller, J. W.; xavier, r. j.; Cummings, R. D.
10.1101/2020.12.22.424076 — neuroscience — Posted on 2020-12-23
691 Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
Raghunandan, A.; Ladron-de-Guevara, A.; Tithof, J.; Mestre, H.; Nedergaard, M.; Thomas, J. H.; Kelley, D. H.
10.1101/2020.11.09.374512 — neuroscience — Posted on 2020-12-23
694 Multi-cellular communities are perturbed in the aging human brain and with Alzheimer's disease
Cain, A.; Taga, M.; McCabe, C.; Hekselman, I.; White, C. C.; Green, G.; Rozenblatt-Rosen, O.; Zhang, F.; Yeger-Lotem, E.; Bennett, D. A.; Yang, H.-S.; Regev, A.; Menon, V.; Habib, N.; De Jager, P.
10.1101/2020.12.22.424084 — neuroscience — Posted on 2020-12-23
695 In Vivo Pharmacokinetic Study of Remdesivir Dry Powder for Inhalation in Hamsters
sahakijpijarn, s.; Moon, C.; Warnken, Z. N.; Maier, E.; DeVore, J. E.; Christensen, D. J.; Koleng, J. J.; Williams, R. O.
10.1101/2020.12.22.424071 — pharmacology and toxicology — Posted on 2020-12-23
696 A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells
Walter, K.; Rodriguez-Aznar, E.; Ventura-Ferreira, M. S.; Frappant, P. O.; Dittrich, T.; Tiwary, K.; Meessen, S.; Lerma, L.; Daiss, N.; Schulte, L. A.; Arnold, F.; Azoitei, N.; Erkan, M.; Lehel, A.; Bruemmendorf, T.; Seufferlein, T.; Kleger, A.; Tabares, E.; Guenes, C.; Beier, F.; Sainz, B.; Hermann, P. C.
10.1101/2020.11.02.361931 — cancer biology — Posted on 2020-12-23
697 De novo coding variants in the AGO1 gene cause a neurodevelopmental disorder with intellectual disability
Schalk, A.; Cousin, M. A.; Challman, T. D.; Wain, K. E.; Powis, Z.; Minks, K.; Trimouille, A.; Lasseaux, E.; Lacombe, D.; Angelini, C.; Michaud, V.; Van-Gils, J.; Spataro, N.; Ruiz, A.; Gabau, E.; Stolerman, E.; Washington, C.; Louie, R. J.; Lanpher, B. C.; Kemppainen, J. L.; Innes, A. M.; Kooy, F.; Meuwissen, M.; Goldenberg, A.; Lecoquierre, F.; Vera, G.; Diderich, K. E. M.; Sheidley, B. R.; El Achkar, C. M.; Park, M.; Hamdan, F. F.; Michaud, J. L.; Lewis, A. J.; Zweier, C.; Reis, A.; Wagner, M.; Weigand, H.; Journel, H.; Keren, B.; Passemard, S.; Mignot, C.; van Gassen, K. L. I.; Brilstra, E
10.1101/2020.12.23.424103 — genetics — Posted on 2020-12-23
701 Orchard management and landscape context mediate the floral microbiome of pear
Schaeffer, R. N.; Pfeiffer, V. W.; Basu, S.; Brousil, M.; Strohm, C.; DuPont, S. T.; Vannette, R.; Crowder, D.
10.1101/2020.12.23.424173 — microbiology — Posted on 2020-12-23
702 Tyrosinase from mushroom Agaricus bisporus as an inhibitor of the Hepatitis C virus
Lopez-Tejedor, D.; Claveria-Gimeno, R.; Velazquez-Campoy, A.; Abian, O.; Palomo, J. M.
10.1101/2020.12.23.424187 — microbiology — Posted on 2020-12-23
706 SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation
Thorne, L. G.; Reuschl, A.-K.; Zuliani-Alvarez, L.; Whelan, M. V. X.; Noursadeghi, M.; Jolly, C.; Towers, G. J.
10.1101/2020.12.23.424169 — microbiology — Posted on 2020-12-23
707 Fitness selection of hyperfusogenic measles virus F proteins associated with neuropathogenic phenotypes
Ikegame, S.; Hashiguchi, T.; Hung, C.-t.; Dobrindt, K.; Brennand, K.; Takeda, M.; Lee, B.
10.1101/2020.12.22.423954 — microbiology — Posted on 2020-12-23
710 mRNA vaccine CVnCoV protects non-human primates from SARS-CoV-2 challenge infection
Rauch, S.; Gooch, K. E.; Hall, Y.; Salguero, F. J.; Dennis, M. J.; Gleeson, F. V.; Harris, D.; Ho, C.; Humphries, H. E.; Longet, S.; Ngabo, D.; Paterson, J.; Rayner, E. L.; Ryan, K. A.; Sharpe, S.; Watson, R. J.; Mueller, S. O.; Petsch, B.; Carroll, M. W.
10.1101/2020.12.23.424138 — immunology — Posted on 2020-12-23
711 Core Circadian Clock Genes Per1 and Per2 regulate the Rhythm in Photoreceptor Outer Segment Phagocytosis
Milicevic, N.; Ait-Hmyed Hakkari, O.; Bagchi, U.; Sandu, C.; Jongejan, A.; Moerland, P. D.; ten Brink, J. B.; Hicks, D.; Bergen, A. A.; Felder-Schmittbuhl, M.-P.
10.1101/2020.12.23.424210 — neuroscience — Posted on 2020-12-23
712 Mechanism of cellular production and in vivo seeding effects of hexameric β-amyloid assemblies
Vrancx, C.; Vadukul, D. M.; Contino, S.; Suelves, N.; D'Auria, L.; Perrin, F.; van Pesch, V.; Hanseeuw, B.; Quinton, L.; Kienlen-Campard, P.
10.1101/2020.12.23.424094 — neuroscience — Posted on 2020-12-23
713 Proteomic and functional analyses of the periodic membrane skeleton in neurons
Zhou, R.; Han, B.; Nowak, R.; Lu, Y.; Heller, E.; Xia, C.; Chishti, A. H.; Fowler, V. M.; Zhuang, X.
10.1101/2020.12.23.424206 — neuroscience — Posted on 2020-12-23
714 Optogenetic Amplification Circuits for Light-Induced Metabolic Control
Zhao, E. M.; Lalwani, M. A.; Chen, J.-M.; Orillac, P.; Toettcher, J. E.; Avalos, J. L.
10.1101/2020.12.23.424152 — synthetic biology — Posted on 2020-12-23
716 Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion
Kim, T. Y.; Jeon, S.; Jang, Y.; Gotina, L.; Won, J.; Ju, Y. H.; Kim, S.; Jang, M. W.; Won, W.; Park, M. G.; Pae, A. N.; Han, S.; Kim, S.; Lee, C. J.
10.1101/2020.12.22.423909 — pharmacology and toxicology — Posted on 2020-12-23
717 Selective Targeting of Ras Mutant Cancers via a New Small Molecule
Tolani, B.; Celli, A.; Yao, Y.; Tan, Y. Z.; Fetter, R.; Liem, C. R.; de Smith, A. J.; Vasanthakumar, T.; Bisignano, P.; Seiple, I. B.; Rubinstein, J. L.; Jost, M.; Weissman, J. S.
10.1101/2020.12.23.423300 — cancer biology — Posted on 2020-12-23
718 Multiplexed experimental strategies for fragment library screening using SPR biosensors
FitzGerald, E. A.; Vagrys, D.; Opassi, G.; Klein, H. F.; Hamilton, D. J.; Boronat, P.; Cederfelt, D.; Talibov, V. O.; Abramsson, M.; Moberg, A.; Lindgren, M. T.; Holmgren, C.; Dobritzsch, D.; Davis, B.; O'Brien, P.; Wijtmans, M.; van Muijlwijk-Koezen, J. E.; Hubbard, R. E.; de Esch, I. J. P.; Danielson, U. H.
10.1101/2020.12.23.424167 — biophysics — Posted on 2020-12-23
719 Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display
Norman, A.; Franck, C.; Christie, M.; Hawkins, P.; Patel, K.; Ashhurst, A.; Aggarwal, A.; Low, J. K.; Siddiquee, R.; Ashley, C.; Steain, M.; Triccas, J. A.; Turville, S. G.; Mackay, J.; Passioura, T.; Payne, R. J.
10.1101/2020.12.22.424069 — biochemistry — Posted on 2020-12-23
720 A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process
Noske, G.; Nakamura, A.; Gawriljuk, V.; Fernandes, R.; Lima, G.; Rosa, H.; Pereira, H.; Zeri, A.; Nascimento, A.; Freire, M.; Oliva, G.; de Godoy, A. S.
10.1101/2020.12.23.424149 — biochemistry — Posted on 2020-12-23
722 Evolution of a virus-like architecture and packaging mechanism in arepurposed bacterial protein
Tetter, S.; Terasaka, N.; Steinauer, A.; Bingham, R. J.; Clark, S.; Scott, A. P.; Patel, N.; Leibundgut, M.; Wroblewski, E.; Ban, N.; Stockley, P. G.; Twarock, R.; Hilvert, D.
10.1101/2020.12.23.423990 — biochemistry — Posted on 2020-12-23
723 Drosophila glue protects from predation
Borne, F.; Prigent, S. R.; Molet, M.; Courtier-Orgogozo, V.
10.1101/2020.12.23.424162 — evolutionary biology — Posted on 2020-12-23
724 SARS-CoV-2 Envelope (E) Protein Interacts with PDZ-Domain-2 of Host Tight Junction Protein ZO1
Shepley-McTaggart, A.; Sagum, C. A.; Oliva, I.; Rybakovsky, E.; DiGuilio, K.; Liang, J.; Bedford, M. T.; Cassel, J.; Sudol, M.; Mullin, J. M.; Harty, R. N.
10.1101/2020.12.22.422708 — microbiology — Posted on 2020-12-23
725 Elucidating the antiviral mechanism of different MARCH proteins
Umthong, S.; Lynch, B.; Timilsina, U.; Waxman, B.; Ivey, E. B.; Stavrou, S.
10.1101/2020.12.22.422953 — microbiology — Posted on 2020-12-23
726 Host Cell Proteases Drive Early or Late SARS-CoV-2 Penetration
Koch, J.; Uckeley, Z. M.; Doldan, P.; Stanifer, M. L.; Boulant, S.; Lozach, P.-Y.
10.1101/2020.12.22.423906 — microbiology — Posted on 2020-12-23
731 Biological Correlations and Confounding Variables for Quantification of Retinal Ganglion Cells Based on Optical Coherence Tomography Using Diversity Outbred Mice
Hedberg-Buenz, A.; Meyer, K. J.; van der Heide, C. J.; Deng, W.; Lee, K.; Soukup, D. A.; Kettelson, M.; Pellack, D.; Mercer, H.; Wang, K.; Garvin, M. K.; Abramoff, M. D.; Anderson, M. G.
10.1101/2020.12.23.423848 — neuroscience — Posted on 2020-12-23
733 Vangl2 regulates the dynamics of Wnt cytonemes in vertebrates
Brunt, L.; Greicius, G.; Evans, B. D.; Virshup, D. M.; Wedgwood, K. C.; Scholpp, S.
10.1101/2020.12.23.424142 — developmental biology — Posted on 2020-12-23
734 EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis
Mukherjee, K.; Xue, L.; Planutis, A.; Gnanapragasam, M. N.; Chess, A.; Bieker, J. J.
10.1101/2020.12.23.424143 — developmental biology — Posted on 2020-12-23
735 Docosahexaenoic fatty acid-containing phospholipids affect plasma membrane susceptibility to disruption by bacterial toxin-induced macroapertures
TSAI, M.-C.; FLEURIOT, L.; JANEL, S.; GONZALEZ-RODRIGUEZ, D.; MOREL, C.; METTOUCHI, A.; DEBAYLE, D.; DALLONGEVILLE, S.; OLIVO-MARIN, J.-C.; ANTONNY, B.; LAFONT, F.; LEMICHEZ, E.; BARELLI, H.
10.1101/2020.12.23.424114 — cell biology — Posted on 2020-12-23
736 Receptor-linked environment-sensitive probe monitors the local membrane environment surrounding the insulin receptor
Umebayashi, M.; Takemoto, S.; Reymond, L.; Sundukova, M.; Hovius, R.; Bucci, A.; Heppenstall, P. A.; Yokota, H.; Johnsson, K.; Riezman, H.
10.1101/2020.12.23.424145 — cell biology — Posted on 2020-12-23
739 MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis
Carroll, P.; Cheng, P.-F.; Freie, B. W.; Kasinathan, S.; Gu, H.; Hedrich, T.; Dowdle, J. A.; Venkataramani, V.; Ramani, V.; Raftery, D.; Shendure, J.; Ayer, D. E.; Muller, C. H.; Eisenman, R. N. N.
10.1101/2020.12.23.424063 — developmental biology — Posted on 2020-12-23
742 Dissociated face- and word-selective intracerebral responses in the human ventral occipito-temporal cortex
Hagen, S.; Lochy, A.; Jacques, C.; Maillard, L.; Colnat-Coulbois, S.; Jonas, J.; Rossion, B.
10.1101/2020.12.23.423819 — neuroscience — Posted on 2020-12-23
743 Narratives: fMRI data for evaluating models of naturalistic language comprehension
Nastase, S. A.; Liu, Y.-F.; Hillman, H.; Zadbood, A.; Hasenfratz, L.; Keshavarzian, N.; Chen, J.; Honey, C. J.; Yeshurun, Y.; Regev, M.; Nguyen, M.; Chang, C. H. C.; Baldassano, C.; Lositsky, O.; Simony, E.; Chow, M. A.; Leong, Y. C.; Brooks, P. P.; Micciche, E.; Choe, G.; Goldstein, A.; Vanderwal, T.; Halchenko, Y. O.; Norman, K. A.; Hasson, U.
10.1101/2020.12.23.424091 — neuroscience — Posted on 2020-12-23
745 Automated prediction of the clinical impact of structural copy number variations
Gaziova, M.; Sladecek, T.; Pos, O.; Stevko, M.; Krampl, W.; Pos, Z.; Hekel, R.; Hlavacka, M.; Kucharik, M.; Radvanszky, J.; Budis, J.; Szemes, T.
10.1101/2020.07.30.228601 — bioinformatics — Posted on 2020-12-23
746 A globally diverse reference alignment and panel for imputation of mitochondrial DNA variants
McInerney, T. W.; Fulton-Howard, B.; Patterson, C.; Paliwal, D.; Jermiin, L. S.; Patel, H. R.; Swerdlow, R. H.; Pa, J.; Goate, A. M.; Easteal, S.; Andrews, S. J.
10.1101/649293 — genomics — Posted on 2020-12-23
749 The role of islet lipid composition remodeling in regulation of beta-cell death via ADP-ribosyl-acceptor glycohydrolase ARH3 signaling in insulitis
Nakayasu, E. S.; Deiter, C.; Kyle, J.; Guney, M.; Sarbaugh, D.; Yin, R.; Cui, Y.; Nicora, C.; Syed, F.; Juan-Mateu, J.; Mirmira, R. G.; Evans-Molina, C.; Eizirik, D. L.; Webb-Robertson, B.-J.; Burnum-Johnson, K.; Orr, G.; Laskin, J.; Metz, T. O.; Sussel, L.; Ansong, C.
10.1101/2020.03.23.004481 — systems biology — Posted on 2020-12-23
751 Evidence for shared ancestry between Actinobacteria and Firmicutes bacteriophages
Koert, M.; Lopez-Perez, J.; Mattson, C.; Caruso, S. M.; Erill, I.
10.1101/842583 — genomics — Posted on 2020-12-23
752 Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions at different rates across generations
Meshnik, L.; Bar-Yaacov, D.; Kasztan, D.; Neiger, T.; Cohen, T.; Kishner, M.; Valenci, I.; Dadon, S.; Klein, C. J.; Vance, J. M.; Nevo, Y.; Zuchner, S.; Mishmar, D.; Ben-Zvi, A.
10.1101/610758 — genetics — Posted on 2020-12-23
753 Ancestral mitochondrial apparatus derived from the bacterial type II secretion system
Horvathova, L.; Zarsky, V.; Panek, T.; Derelle, R.; Pyrih, J.; Motyckova, A.; Klapstova, V.; Vinopalova, M.; Markova, L.; Voleman, L.; Klimes, V.; Petru, M.; Vaitova, Z.; Cepicka, I.; Hryzakova, K.; Harant, K.; Gray, M. W.; Chami, M.; Guilvout, I.; Francetic, O.; Lang, B. F.; Vlcek, C.; Tsaousis, A. D.; Elias, M.; Dolezal, P.
10.1101/790865 — evolutionary biology — Posted on 2020-12-23
758 WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization
Walker, M. D.; Giese, G. E.; Holdorf, A. D.; Bhattacharya, S.; Diot, C.; Horowitz, B. B.; Garcia-Gonzalez, A. P.; Lee, Y.-U.; Leland, T.; Li, X.; Mirza, Z.; Na, H.; Nanda, S.; Ponomarova, O.; Zhang, H.; Zhang, J.; Yilmaz, L. S.; Walhout, M.
10.1101/2020.12.22.424026 — genetics — Posted on 2020-12-23
759 A WDR35/IFT121-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia
Quidwai, T.; Hall, E. A.; Keighren, M. A.; Leng, W.; Kiesel, P.; Wells, J. N.; Murphy, L. C.; Marsh, J. A.; Pigino, G.; Mill, P.
10.1101/2020.12.22.423978 — cell biology — Posted on 2020-12-23
760 FAM72A antagonizes UNG2 to promote mutagenic uracil repair during antibody maturation
Feng, Y.; Li, C.; Stewart, J.; Barbulescu, P.; Seija Desivo, N.; Alvarez Quilon, A.; Pezo, R.; Perera, M.; Chan, K.; Tong, A.; Mohamad-Ramshan, R.; Berru, M.; Nakib, D.; Li, G.; Kardar, G.; Carlyle, J.; Moffat, J.; Durocher, D.; Di Noia, J.; Bhagwat, A.; Martin, A.
10.1101/2020.12.23.423975 — immunology — Posted on 2020-12-23
761 Control of polyunsaturated fatty acids desaturation by Sting regulates inflammatory responses
Vila, i. K.; Chamma, H.; Steer, A.; Taffoni, C.; Reinert, L. S.; Turtoi, E.; Saccas, M.; Marines, J.; Jin, L.; Bonnefont, X.; Paludan, S. R.; Vlachakis, D.; Turtoi, A.; Laguette, N.
10.1101/2020.12.22.423950 — immunology — Posted on 2020-12-23
762 Fam72a controls the balance between error-prone and error-free DNA repair during antibody diversification.
Rogier, M.; Moritz, J.; Robert, I.; Lescale, C.; Heyer, V.; Thomas-Claudepierre, A.-S.; Abello, A.; Deriano, L.; Reina-San-Martin, B.
10.1101/2020.12.22.424012 — immunology — Posted on 2020-12-23
765 Genetically engineered retina for improved retinal reconstruction after transplantation
Matsuyama, T.; Tu, H.-Y.; Sun, J.; Hashiguchi, T.; Akiba, R.; Sho, J.; Fujii, M.; Onishi, A.; Takahashi, M.; Mandai, M.
10.1101/2020.12.23.424068 — neuroscience — Posted on 2020-12-23
767 Distinct VIP interneurons in the cingulate cortex encode anxiogenic and social stimuli
Johnson, C.; Kretsge, L. N.; Yen, W. W.; Sriram, B.; Jimenez, J. C.; Jinadasa, T. J.; O'Connor, A.; Liu, R. S.; Nguyen, T. P.; Cho, E. S.; Fuchs, E.; Spevack, E. D.; Escude Velasco, B.; Hausmann, F. S.; Cruz-Martin, A.
10.1101/2020.12.22.424056 — neuroscience — Posted on 2020-12-23
768 Chlorzoxazone, A BKCa Channel Agonist, Rescues The Pathological Phenotypes Of Williams-Beuren Syndrome In A Preclinical Model
Piquemal, M.; Abdulkarim-Abdalla, N.; Ortiz-Romero, P.; Lemaire-Mayo, V.; Crusio, W. E.; Louette, E.; Pietropaolo, S.
10.1101/2020.12.22.423977 — neuroscience — Posted on 2020-12-23
771 Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating the interleukin-6-Hsp70 axis through inter-organ crosstalk
Clemens, M. M.; Kennon-McGill, S.; Vazquez, J. H.; Stephens, O. W.; Peterson, E. A.; Johann, D. J.; Allard, F. D.; Yee, E. U.; McCullough, S. S.; James, L. P.; Finck, B. N.; McGill, M. R.
10.1101/2020.12.22.423312 — pharmacology and toxicology — Posted on 2020-12-23
772 New look at RSV infection : tissue clearing and 3D imaging of the entire mouse lung at cellular resolution.
Fretaud, M.; Descamps, D.; Laubreton, D.; Rameix-Welti, M.-A.; Eleouet, J. F.; Larcher, T.; Galloux, M.; langevin, C.
10.1101/2020.12.23.424099 — pathology — Posted on 2020-12-23
779 Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, S.; Boi, D.; Boumis, G.; Lucchi, R.; Liberati, F. R.; Capelli, D.; Montanari, R.; Pochetti, G.; Paone, A.; Rinaldo, S.; Contestabile, R.; Paiardini, A.; Tramonti, A.; Giardina, G.; Cutruzzola, F.
10.1101/2020.12.23.423904 — biochemistry — Posted on 2020-12-23
780 Human Polyomavirus-Encoded Circular RNAs
Yang, R.; Lee, E.; Kim, J.; Choi, J. H.; Chen, E.; Crewe, C.; Scherer, P. E.; Kolitz, E.; Cockerell, C.; Smith, T. R.; Rosen, L.; Verlinden, L.; Feltkamp, M. C.; Sullivan, C. S.; Wang, R.
10.1101/2020.12.22.423831 — molecular biology — Posted on 2020-12-23
786 A non-enzymatic acetylation of lysine residues adversely affects the Rubisco activase protein stability
Yang, L.; Hong, H.; Gao, X.; Essemine, J.; Fang, X.; Shu, Z.; Ablat, G.; Wu, M.; Mi, H.-L.; Chen, X.-Y.; Qu, M.; Chen, G.-Y.
10.1101/2020.12.21.423885 — plant biology — Posted on 2020-12-23
787 Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
Rahman, A. M.; Engelsen, A. S. T.; Sarowar, S.; Bindesboll, C.; Birkeland, E.; Lotsberg, M. L.; Knappskog, S.; Simonsen, A.; Chekenya, M.
10.1101/2020.12.20.423718 — cancer biology — Posted on 2020-12-23
788 Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes
Hindy, G.; Dornbos, P.; Chaffin, M. D.; Liu, D. J.; Wang, M. X.; Aguilar-Salinas, C. A.; Antonacci-Fulton, L.; Ardissino, D.; Arnett, D. K.; Aslibekyan, S.; Atzmon, G.; Ballantyne, C. M.; Barajas-Olmos, F.; Barzilai, N.; Becker, L. C.; Bielak, L. F.; Bis, J. C.; Blangero, J.; Boerwinkle, E.; Bonnycastle, L. L.; Bottinger, E.; Bowden, D. W.; Bown, M. J.; Brody, J. A.; Broome, J. G.; Burtt, N. P.; Cade, B. E.; Centeno-Cruz, F.; Chan, E.; Chang, Y.-C.; Chen, Y.-D. I.; Cheng, C.-Y.; Choi, W. J.; Chowdhury, R.; Contreras-Cubas, C.; Cordova, E. J.; Correa, A.; Cupples, L. A.; Curran, J. E.; Danesh,
10.1101/2020.12.22.423783 — genetics — Posted on 2020-12-23
790 In vivo-mimicking 3D cultures secrete distinct extracellular vesicles upon cancer cell invasion
Henriksson, E.; Luoto, J. C.; Coelho-Rato, L. S.; Bengs, S. H.; Roininen, J.; Eriksson, J. E.; Sistonen, L.
10.1101/2020.12.22.423913 — cell biology — Posted on 2020-12-23
791 KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism
Ruberto, A. A.; Grechez-Cassiau, A.; Guerin, S.; Martin, L.; Revel, J. S.; Mehiri, M.; Subramaniam, M.; Delaunay, F.; Teboul, M.
10.1101/2020.12.22.423999 — cell biology — Posted on 2020-12-23
792 SARS-CoV-2 RNA quantification using droplet digital RT-PCR
Kinloch, N. N.; Ritchie, G.; Dong, W.; Cobarrubias, K. D.; Sudderuddin, H.; Lawson, T.; Matic, N.; Montaner, J. S. G.; Leung, V.; Romney, M. G.; Lowe, C. F. J.; Brumme, C. J.; Brumme, Z. L.
10.1101/2020.12.21.423898 — molecular biology — Posted on 2020-12-23
794 Functional diversity of isoprenoidal lipids in Methylobacterium extorquens PA1
Rizk, S.; Henke, P.; Santana-Molina, C.; Martens, G.; Gnädig, M.; devos, d. p.; Neumann-Schaal, M.; Saenz, J. P.
10.1101/2020.12.21.423902 — microbiology — Posted on 2020-12-23
795 A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection
Lebratti, T.; Lim, Y. S.; Cofie, A.; Andhey, P.; Jiang, X.; Scott, J.; Fabbrizi, M. R.; Ozantürk, A. N.; Pham, C.; Clemens, R.; Artyomov, M.; Dinauer, M.; Shin, H.
10.1101/2020.12.20.423690 — immunology — Posted on 2020-12-23
796 Transforming representations of movement from body- to world-centric space
Lu, J.; Westeinde, E. A.; Hamburg, L.; Dawson, P. M.; Lyu, C.; Maimon, G.; Druckmann, S.; Wilson, R. I.
10.1101/2020.12.22.424001 — neuroscience — Posted on 2020-12-23
798 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; McKinnon, C.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-12-23
801 Methane emission of humans is explained by dietary habits, host genetics, local formate availability and a uniform archaeome
Kumpitsch, C.; Fischmeister, F.; Mahnert, A.; Lackner, S.; Wilding, M.; Sturm, C.; Springer, A.; Madl, T.; Holasek, S.; Hoegenauer, C.; Berg, I.; Schoepf, V.; Moissl-Eichinger, C.
10.1101/2020.12.21.423794 — microbiology — Posted on 2020-12-23
805 Integrated Collection of Stem Cell Bank data, a data portal for standardized stem cell information
Chen, Y.; Sakurai, K.; Maeda, S.; Masui, T.; Okano, H.; Dewender, J.; Seltmann, S.; Kurtz, A.; Masuya, H.; Nakamura, Y.; Sheldon, M.; Schneider, J.; Stacey, G.; Panina, Y.; Fujibuchi, W.
10.1101/2020.08.26.263830 — bioinformatics — Posted on 2020-12-23
806 Annotation and analysis of yellow genes in Asian citrus psyllid, Diaphorina citri, vector for the Huanglongbing disease
Massimino, C.; Vosburg, C.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Benoit, J. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.12.22.422960 — genomics — Posted on 2020-12-22
808 Bursting firing in ventromedial hypothalamic neurons exerts dual control of anxiety-like behavior and energy expenditure
Shao, J.; Gao, D.; Liu, Y.; Chen, S.; Liu, N.; Zhang, L.; Zhou, X.; Xiao, Q.; Wang, L.; Hu, H.; Yang, F.
10.1101/2020.12.20.423695 — neuroscience — Posted on 2020-12-22
811 Identification of the toxic 6mer seed consensus in human cancer cells
Patel, M.; Bartom, E. T.; Paudel, B.; Kocherginsky, M.; O'Shea, K. L.; Murmann, A. E.; Peter, M. E.
10.1101/2020.12.22.424040 — cancer biology — Posted on 2020-12-22
816 A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs
Nguyen, T.; Phan, K. L.; Kreitler, D. F.; Andrews, L. C.; Gabelli, S. B.; Kozakov, D.; Jakoncic, J.; Sweet, R. M.; Soares, A.; Bernstein, H. J.
10.1101/2020.12.14.422680 — molecular biology — Posted on 2020-12-22
817 Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocyte accumulating hepatitis B surface antigen
Baudi, I.; Isogawa, M.; Moalli, F.; Onishi, M.; Kawashima, K.; Sato, Y.; Harashima, H.; Ito, H.; Ishikawa, T.; Wakita, T.; Iannacone, M.; Tanaka, Y.
10.1101/2020.12.22.423938 — microbiology — Posted on 2020-12-22
818 Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are key features of alpacas resolving MERS-CoV infection
Te, N.; Rodon, J.; Ballester, M.; Perez, M.; Pailler-Garcia, L.; Segales, J.; Vergara-Alert, J.; Bensaid, A.
10.1101/2020.12.22.423939 — immunology — Posted on 2020-12-22
819 RORα enforces stability of the T-helper-17 cell effector program
Lee, J.-Y.; Hall, J. A.; Pokrovskii, M.; Kroehling, L.; Wu, L.; Littman, D. R.
10.1101/2020.12.15.422921 — immunology — Posted on 2020-12-22
820 Transduction catalysis:doxorubicin accelerates and enhances rAAV-mediated gene expression in the cortex of mouse, cat and monkey
gong, h.; Yuan, N.; Shen, Z.; Tang, C.; Shipp, S.; Qian, L.; Lu, Y.; Andolina, I. M.; Zhang, S.; Wu, J.; Yang, H.; Wang, W.
10.1101/2020.06.08.139667 — neuroscience — Posted on 2020-12-22
821 A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection
Hulse, B. K.; Haberkern, H.; Franconville, R.; Turner-Evans, D. B.; Takemura, S.-y.; Wolff, T.; Noorman, M.; Dreher, M.; Dan, C.; Parekh, R.; Hermundstad, A. M.; Rubin, G. M.; Jayaraman, V.
10.1101/2020.12.08.413955 — neuroscience — Posted on 2020-12-22
822 Physiological and pathological changes in the enteric nervous system of rotenone-exposed mice as potential early biomarkers for Parkinson's disease
Schaffernicht, G.; Shang, Q.; Stievenard, A.; Bötzel, K.; Dening, Y.; Kempe, R.; Toussaint, M.; Gündel, D.; Kranz, M.; Reichmann, H.; Vanbesien-Mailliot, C.; Brust, P.; Dieterich, M.; Funk, R. H. W.; Ravens, U.; Pan-Montojo, F. J.
10.1101/2020.12.11.421164 — neuroscience — Posted on 2020-12-22
826 Organ geometry channels cell fate in the Arabidopsis ovule primordium
Hernandez-Lagana, E.; Mosca, G.; Mendocilla Sato, E.; Pires, N.; Frey, A.; Giraldo-Fonseca, A.; Grossniklaus, U.; Hamant, O.; Godin, C.; Boudaoud, A.; Grimanelli, D.; Autran, D.; Baroux, C.
10.1101/2020.07.30.226670 — plant biology — Posted on 2020-12-22
827 Self-similar synchronization of calcium and membrane potential transitions during AP cycles predict HR across species
Tagirova (Sirenko), S.; Tsutsui, K.; Tarasov, K. V.; Yang, D.; Wirth, A. N.; Maltsev, V. A.; Ziman, B. D.; Yaniv, Y.; Lakatta, E. G.
10.1101/2020.10.26.355412 — physiology — Posted on 2020-12-22
834 Diversification of mammalian deltaviruses by host shifting
Bergner, L.; Orton, R.; Broos, A.; Tello, C.; Becker, D.; Carrera, J.; Patel, A.; Biek, R.; Streicker, D.
10.1101/2020.06.17.156745 — evolutionary biology — Posted on 2020-12-22
837 TENT4A non-canonical poly(A) polymerase regulates DNA-damage tolerance via multiple pathways which are mutated in endometrial cancer
Swain, U.; Friedlander, G.; Sehrawat, U.; Sarusi-Portuguez, A.; Rotkopf, R.; Ebert, C.; Paz-Elizur, T.; Dikstein, R.; Carell, T.; Geacintov, N.; Livneh, Z.
10.1101/2020.12.03.409367 — molecular biology — Posted on 2020-12-22
838 Unexpected plasticity in the life cycle of Trypanosoma brucei
Schuster, S.; Lisack, J.; Subota, I.; Zimmermann, H.; Reuter, C.; Morriswood, B.; Engstler, M.; Lisack, J.
10.1101/717975 — microbiology — Posted on 2020-12-22
839 Niche and local geography shape the pangenome of wastewater- and livestock-associated Enterobacteriaceae
Shaw, L. P.; Chau, K. K.; Kavanagh, J.; AbuOun, M.; Stubberfield, E.; Gweon, H. S.; Barker, L.; Rodger, G.; Bowes, M. J.; Hubbard, A. T. M.; Pickford, H.; Swann, J.; Gilson, D.; Smith, R. P.; Hoosdally, S. J.; Sebra, R.; Brett, H.; Peto, T. E. A.; Bailey, M. J.; Crook, D. W.; Read, D. S.; Anjum, M. F.; Walker, A. S.; Stoesser, N.; REHAB consortium,
10.1101/2020.07.23.215756 — microbiology — Posted on 2020-12-22
840 Metabolomic signature of the maternal microbiota in the fetus
Pessa-Morikawa, T.; Husso, A.; Kärkkäinen, O.; Koistinen, V.; Hanhineva, K.; Iivanainen, A.; Niku, M.
10.1101/2020.09.28.317081 — microbiology — Posted on 2020-12-22
842 A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
Vizioli, L.; Moeller, S.; Dowdle, L.; Akcakaya, M.; De Martino, F.; Yacoub, E.; Ugurbil, K.
10.1101/2020.11.04.368357 — neuroscience — Posted on 2020-12-22
845 A scale-dependent measure of system dimensionality
Recanatesi, S.; Bradde, S.; Balasubramanian, V.; Steinmetz, N. A.; Shea-Brown, E.
10.1101/2020.12.19.423618 — neuroscience — Posted on 2020-12-22
847 Neural substrates of verbal repetition deficits in primary progressive aphasia
Miller, H. E.; Cordella, C.; Collins, J. A.; Ezzo, R.; Quimby, M.; Hochberg, D.; Tourville, J. A.; Dickerson, B. C.; Guenther, F. H.
10.1101/2020.10.27.357038 — neuroscience — Posted on 2020-12-22
849 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; McKinnon, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-12-22
850 Single Layers of Attention Suffice to Predict Protein Contacts
Bhattacharya, N.; Thomas, N.; Rao, R.; Dauparas, J.; Koo, P.; Baker, D.; Song, Y. S.; Ovchinnikov, S.
10.1101/2020.12.21.423882 — bioinformatics — Posted on 2020-12-22
851 Global Geographic and Temporal Analysis of SARS-CoV-2 Haplotypes Normalized by COVID-19 Cases during the Pandemic
Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa Robles, C.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Uceda-Campos, G.; Pineda Chavarria, R.
10.1101/2020.07.12.199414 — genomics — Posted on 2020-12-22
852 Characterization of chitin deacetylase genes in the Diaphorina citri genome
Miller, S.; Shippy, T.; Tamayo, B.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.12.22.424074 — genomics — Posted on 2020-12-22
853 Consistent variations in personality traits and their potential for genetic improvement of biocontrol agents: Trichogramma evanescens as a case study
Lartigue, S.; Yalaoui, M.; Belliard, J.; Caravel, C.; Jeandroz, L.; Groussier, G.; Calcagno, V.; Louapre, P.; Dechaume-Moncharmont, F.-X.; Malausa, T.; Moreau, J.
10.1101/2020.08.21.257881 — ecology — Posted on 2020-12-22
856 Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord
Arulkandarajah, K. H.; Osterstock, G.; Lafont, A.; Le Corronc, H.; Escalas, N.; Corsini, S.; Le Bras, B.; Boeri, J.; Czarnecki, A.; Mouffle, C.; Bullier, E.; Hong, E.; Soula, C.; Legendre, P.; Mangin, J.-M.
10.1101/2020.05.23.111955 — neuroscience — Posted on 2020-12-22
857 Microstructural characterization and validation of a 3D printed axon-mimetic phantom for diffusion MRI
Mushtaha, F. N.; Kuehn, T. K.; El-Deeb, O.; Rohani, S. A.; Helpard, L. W.; Moore, J.; Ladak, H.; Moehring, A.; Baron, C. A.; Khan, A. R.
10.1101/2020.07.02.185397 — neuroscience — Posted on 2020-12-22
863 Sesbanimide R, a novel cytotoxic polyketide produced by magnetotactic bacteria
Awal, R. P.; Haack, P. A.; Bader, C. D.; Riese, C. N.; Schüler, D.; Müller, R.
10.1101/2020.12.22.424014 — microbiology — Posted on 2020-12-22
864 T cell activation, highly armed cytotoxic cells and a sharp shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19
Zenarruzabeitia, O.; Astarloa-Pando, G.; Terren, I.; Orrantia, A.; Perez-Garay, R.; Seijas-Betolaza, I.; Nieto-Arana, J.; Imaz-Ayo, N.; Perez-Fernandez, S.; Arana-Arri, E.; Borrego, F.
10.1101/2020.12.22.423917 — immunology — Posted on 2020-12-22
865 Creation and validation of 3D-printed head molds for stereotaxic injections of neonatal mouse brains
Chervonski, E.; Brockman, A.; Khurana, R.; Chen, Y.; Greenberg, S.; Hay, M. S.; Luo, Y.; Miller, J.; Patelis, D.; Whitney, S. K.; Walker, M.; Ihrie, R. A.
10.1101/2020.12.22.424033 — neuroscience — Posted on 2020-12-22
868 Rapid 40 kb genome construction from 52 parts
Pryor, J. M.; Potapov, V.; Pokhrel, N.; Lohman, G. J. S.
10.1101/2020.12.22.424019 — synthetic biology — Posted on 2020-12-22
869 A WD40 repeat-like protein pathway connects F-BOX STRESS INDUCED (FBS) proteins to the NIGT1.1 transcriptional repressor in Arabidopsis
Sepulveda-Garcia, E.; Fulton, E. C.; Parlan, E. V.; Brauning, A. A.; O'Connor, L. E.; Fleming, A. A.; Replogle, A. J.; Rocha-Sosa, M.; Gendron, J. M.; Thines, B.
10.1101/2020.12.22.424016 — plant biology — Posted on 2020-12-22
870 15-PGDH as a Negative Regulator of Age-Related Organ Fitness
Ho, W. J.; Smith, J. N. P.; Park, Y. S.; Hadiono, M.; Christo, K. F.; Jogasuria, A.; Zhang, Y.; Broncano, A. V.; Kasturi, L.; Dawson, D. M.; Gerson, S. L.; Markowitz, S. D.; Desai, A. B.
10.1101/2020.12.22.424017 — pathology — Posted on 2020-12-22
871 In vivo genetic screen identifies a SLC5A3-dependent myo-inositol auxotrophy in acute myeloid leukemia
Wei, Y.; Iyer, S.; Costa, S.; Yang, Z.; Kramer, M.; Adelman, E.; Klingbeil, O.; Demerdash, O.; Polyanskaya, S.; Chang, K.; Goodwin, S.; Hodges, E.; McCombie, W. R.; Figueroa, M.; Vakoc, C.
10.1101/2020.12.22.424018 — cancer biology — Posted on 2020-12-22
872 Identification of the toxic 6mer seed consensus in human cancer cells
Patel, M.; Bartom, E. T.; Paudel, B.; Kocherginsky, M.; O'Shea, K. L.; Murmann, A. E.; Peter, M. E.
10.1101/2020.12.22.424040 — cancer biology — Posted on 2020-12-22
874 Structure of the antidiuretic hormone vasopressin receptor signalling complex.
Bous, J.; Orcel, H.; Floquet, N.; Leyrat, C.; Lai-Kee-Him, J.; Gaibelet, G.; Ancelin, A.; Saint-Paul, J.; Trapani, S.; Louet, M.; Sounier, R.; Demene, H.; Granier, S.; Bron, P.; Mouillac, B.
10.1101/2020.12.22.424028 — biochemistry — Posted on 2020-12-22
875 SARS-CoV-2 Genomic Surveillance in Costa Rica: Evidence of a Divergent Population and an Increased Detection of a Spike T1117I Mutation
Molina Mora, J. A.; Cordero-Laurent, E.; Godinez, A.; Calderon, M.; Brenes, H.; Soto-Garita, C.; Perez-Corrales, C.; COINGESA-CR Consorcio Interinstitucional de Estudios Genomicos del SARS-CoV-2 Costa Rica, ; Drexler, J. F.; Moreira-Soto, A.; Corrales-Aguilar, E.; Duarte-Martinez, F.
10.1101/2020.12.21.423850 — genomics — Posted on 2020-12-22
876 Evolutionary tracking of SARS-CoV-2 genetic variants highlights intricate balance of stabilizing and destabilizing mutations
Jacob, J. J.; Vasudevan, K.; Pragasam, A. K.; Gunasekaran, K.; Kang, G.; Veeraraghavan, B.; Mutreja, A.
10.1101/2020.12.22.423920 — genomics — Posted on 2020-12-22
877 The evolutionary assembly of forest communities along environmental gradients: recent diversification or sorting of pre-adapted clades?
Linan, A. G.; Myers, J. A.; Edwards, C. E.; Zanne, A. E.; Smith, S. A.; Arellano, G.; Cayola, L.; Farfan-Rios, W.; Fuentes, A. F.; Garcia-Cabrera, K.; Gonzales-Caro, S.; Loza, M. I.; Macia, M. J.; Malhi, Y.; Nieto-Ariza, B.; Salinas, N.; Silman, M. R.; Tello, S. J.
10.1101/2020.12.22.424032 — ecology — Posted on 2020-12-22
879 Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection
Chang, J. J.- Y.; Rawlinson, D.; Pitt, M. E.; Taiaroa, G.; Gleeson, J.; Zhou, C.; Mordant, F. L.; De Paoli-Iseppi, R.; Caly, L.; Purcell, D. F. J.; Stinear, T. P.; Londrigan, S. L.; Clark, M. B.; Williamson, D. A.; Subbarao, K.; Coin, L. J. M.
10.1101/2020.12.22.423893 — microbiology — Posted on 2020-12-22
883 Characterizing intra-tumor and inter-tumor variability of immune cell infiltrates in murine syngeneic tumors
Mojtahedzadeh, S.; Opsahl, A.; Aguilar, J.-K.; Li, D.; Streiner, N.; Wang, J.; Trajkovic, D.; Boucher, G.; Coskran, T.; O'Neil, S. P.; Ram, S.
10.1101/2020.12.22.423997 — cancer biology — Posted on 2020-12-22
885 The Ensembl COVID-19 resource: Ongoing integration of public SARS-CoV-2 data
De Silva, N. H.; Bhai, J.; Chakiachvili, M.; Contreras-Moreira, B.; Cummins, C.; Frankish, A.; Gall, A.; Genez, T.; Howe, K. L.; Hunt, S. E.; Martin, F. J.; Moore, B.; Ogeh, D.; Parker, A.; Parton, A.; Ruffier, M.; Pandian Sakthivel, M.; Sheppard, D.; Tate, J.; Thormann, A.; Thybert, D.; Trevanion, S. J.; Winterbottom, A.; Zerbino, D. R.; Finn, R. D.; Flicek, P.; Yates, A. D.
10.1101/2020.12.18.422865 — bioinformatics — Posted on 2020-12-22
889 Novel roles for BicD in pronuclear fusion and meiosis II progression via localization of the CHC/TACC/Msps complex to MII spindles
Vazquez Pianzola, M. P.; Beuchle, D.; Saro, G.; Hernandez, G.; Maldonado, G.; Brunssen, D.; Meister, P.; Suter, B.
10.1101/2020.12.22.423980 — developmental biology — Posted on 2020-12-22
895 Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells
Urbancic, I.; Schiffelers, L.; Jenkins, E.; Gong, W.; Santos, A. M.; Schneider, F.; O'Brien-Ball, C.; Vuong, M. T.; Ashman, N.; Sezgin, E.; Eggeling, C.
10.1101/2020.12.22.422352 — biophysics — Posted on 2020-12-22
897 Conversion between 100-million-year-old duplicated genes contributes to rice subspecies divergence
Wang, J.; Wang, L.; Wei, C.; Wang, J.; Teng, J.; Shen, S.; Xiao, Q.; Bao, S.; Feng, Y.; Zhang, Y.; Li, Y.; Sun, S.; Yue, Y.; Wu, C.; Wang, Y.; Zhou, T.; Xu, W.; Yu, J.
10.1101/2020.12.22.424042 — bioinformatics — Posted on 2020-12-22
901 Unearthing the genes of plant-beneficial marine yeast - Wickerhamomyces anomalus strain MSD1
Krishnan, R. S.; Narayanasamy, P.; Kumaravel, S. R.; Radhakrishnan, S.; Ponni, K.; Narayanan, L.; Latha, K.
10.1101/2020.12.22.424010 — genomics — Posted on 2020-12-22
905 Dissecting human skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses
He, J.; Yan, J.; Wang, J.; Zhao, L.; Xin, Q.; Zeng, Y.; Sun, Y.; Zhang, H.; Bai, Z.; Li, Z.; Ni, Y.; Gong, Y.; Li, Y.; He, H.; Bian, Z.; Lan, Y.; Ma, C.; Bian, L.; Zhu, H.; Liu, B.; Yue, R.
10.1101/2020.12.22.423948 — developmental biology — Posted on 2020-12-22
906 From egg to adult: a developmental table of the ant Monomorium pharaonis
Pontieri, L.; Rajakumar, A.; Rafiqi, A. M.; Larsen, R. S.; Abouheif, E.; Zhang, G.
10.1101/2020.12.22.423970 — developmental biology — Posted on 2020-12-22
908 Identification of molecular candidates which regulate calcium-dependent CD8+ T-cell cytotoxicity
Zöphel, S.; Schwär, G.; Nazarieh, M.; Konetzki, V.; Hoxha, C.; Meese, E.; Hoth, M.; Helms, V.; Hamed, M.; Schwarz, E. C.
10.1101/2020.12.22.423945 — immunology — Posted on 2020-12-22
909 CRISPR-based functional genomics in human dendritic cells
Jost, M.; Jacobson, A. N.; Hussmann, J. A.; Cirolia, G.; Fischbach, M.; Weissman, J. S.
10.1101/2020.12.22.423985 — immunology — Posted on 2020-12-22
910 In vitro characterisation and neurosteroid treatment of an N-Methyl-D-Aspartate receptor antibody-mediated seizure model
Wright, S. K.; Rosch, R. E.; Wilson, M. A.; Upadhya, M. A.; Dhangar, D. R.; Clarke-Bland, C.; Wahid, T. T.; Barman, S.; Goebels, N.; Kreye, J.; Pruss, H.; Jacobson, L.; Bassett, D. S.; Vincent, A.; Greenhill, S. D.; Woodhall, G. L.
10.1101/2020.12.22.423962 — neuroscience — Posted on 2020-12-22
911 GABA relates to functional connectivity changes and retention in visuomotor adaptation
Nettekoven, C. R.; Brady, S.; Clarke, W. T.; Emir, U.; Levensteion, J.; Petitet, P.; Panouilleres, M. T. N.; Bachtiar, V.; O'Shea, J.; Johansen-Berg, H.; Jenkinson, N.; Stagg, C.
10.1101/2020.12.22.423981 — neuroscience — Posted on 2020-12-22
913 Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation
Brunner, A.-D.; Thielert, M.; Vasilopoulou, C.; Ammar, C.; Coscia, F.; Mund, A.; Horning, O. B.; Bache, N.; Apalategui, A.; Lubeck, M.; Raether, O.; Park, M.; Richter, S.; Fischer, D. S.; Theis, F. J.; Meier, F.; Mann, M.
10.1101/2020.12.22.423933 — systems biology — Posted on 2020-12-22
917 Cell cycle corruption in a preleukemic ETV6-RUNX1 model exposes RUNX1 addiction as a therapeutic target in acute lymphoblastic leukemia
Wray, J. P.; Deltcheva, E. M.; Boiers, C.; Richardson, S. E.; Chettri, J. B.; Gagrica, S.; Guo, Y.; Illendula, A.; Martens, J. H.; Stunnenberg, H. H.; Bushweller, J. H.; Nimmo, R.; Enver, T.
10.1101/2020.12.22.423823 — cancer biology — Posted on 2020-12-22
919 Computational prediction of CRISPR-impaired non-coding regulatory regions
Baumgarten, N.; Schmidt, F.; Wegner, M.; Hebel, M.; Kaulich, M.; Schulz, M. H.
10.1101/2020.12.22.423923 — bioinformatics — Posted on 2020-12-22
921 SUMO maintains the chromatin environment of human induced pluripotent stem cells.
Mojsa, B.; Tatham, M. H.; Davidson, L.; Liczmanska, M.; Wright, J. E.; Wiechens, N.; Gierlinski, M. T.; Owen-Hughes, T.; Hay, R. T.
10.1101/2020.12.22.423944 — cell biology — Posted on 2020-12-22
922 Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis
Bufe, A.; Garcia del Arco, A.; Hennecke, M.-I.; Ostermaier, M.; de Jaime-Soguero, A.; Lin, Y.-C.; Ciprianidis, A.; Engel, U.; Beli, P.; Bastians, H.; Acebron, S. P.
10.1101/2020.12.22.404020 — cell biology — Posted on 2020-12-22
924 Unusual Features of the Membrane Kinome of Trypanosoma brucei
Jensen, B. C.; Vaney, P.; Flaspohler, J.; Coppens, I.; Parsons, M.
10.1101/2020.12.08.416529 — molecular biology — Posted on 2020-12-22
925 Lactoferrin as potential supplementary nutraceutical agent in COVID-19 patients: in vitro and in vivo preliminary evidences
Campione, E.; Lanna, C.; Cosio, T.; Rosa, L.; Conte, M. P.; Iacovelli, F.; Romeo, A.; Falconi, M.; Del Vecchio, C.; Franchin, E.; Lia, M. S.; Minieri, M.; Chiaramonte, C.; Ciotti, M.; Nuccetelli, M.; Terrinoni, A.; Bernardini, S.; Coppeda, L.; Magrini, A.; Miani, A.; Sarmati, L.; Piscitelli, P.; Moricca, N.; Sabatini, S.; Di Lorenzo, A.; Iannuzzi, I.; Rosapepe, F.; Bartoletti, P. L.; Andreoni, M.; Valenti, P.; Bianchi, L.
10.1101/2020.08.11.244996 — microbiology — Posted on 2020-12-22
926 THE URINARY MICROBIOME IN POSTMENOPAUSAL WOMEN WITH RECURRENT URINARY TRACT INFECTIONS
Vaughan, M. H.; Mao, J.; Karstens, L.; Ma, L.; Amundsen, C. L.; Schmader, K. E.; Siddiqui, N. Y.
10.1101/2020.12.21.423901 — microbiology — Posted on 2020-12-22
927 Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
De La Rossa, A.; Laporte, M. H.; Astori, S.; Marissal, T.; Montessuit, S.; Sheshadri, P.; Ramos-Fernández, E.; Mendez, P.; Khani, A.; Quairiaux, C.; Taylor, E.; Rutter, J.; Nunes, J. M.; carleton, a.; Duchen, M.; Sandi, C.; Martinou, J.-C.
10.1101/2020.12.22.423903 — neuroscience — Posted on 2020-12-22
930 Is the brain macroscopically linear? A system identification of resting state dynamics
Nozari, E.; Stiso, J.; Caciagli, L.; Cornblath, E. J.; He, X.; Bertolero, M. A.; Mahadevan, A. S.; Pappas, G. J.; Bassett, D. S.
10.1101/2020.12.21.423856 — neuroscience — Posted on 2020-12-22
932 GNS561, a new autophagy inhibitor active against cancer stem cells in hepatocellular carcinoma and hepatic metastasis from colorectal cancer
Brun, S.; Pascussi, J.-M.; Gifu, E. P.; Bestion, E.; Macek-Jilkova, Z.; Wang, G.; Bassissi, F.; Mezouar, S.; Courcamberck, J.; Merl, P.; Decaens, T.; Pannequin, J.; Halfon, P.; Caron de Fromentel, C.
10.1101/2020.12.21.423741 — cancer biology — Posted on 2020-12-22
934 LISA: Learned Indexes for DNA Sequence Analysis
Ho, D.; Kalikar, S.; Misra, S.; Ding, J.; Md, V.; Tatbul, N.; Li, H.; Kraska, T.
10.1101/2020.12.22.423964 — bioinformatics — Posted on 2020-12-22
938 Dynamic Methylome Modification associated with mutational signatures in ageing and etiology of disease
Kumar, G.; Krishnasamy, K.; Pasha, N.; Nagarajan, N.; Mam, B.; Kishinani, M.; Vohra, V.; Morawala Patell, V.
10.1101/2020.12.22.423778 — genomics — Posted on 2020-12-22
939 Genomic Insights of an Andean Multi-resistant Soil Actinobacterium of Biotechnological Interest
Alonso-Reyes, D. G.; Galvan, F. S.; Portero, L. R.; Alvarado, N. N.; Farias, M. E.; Vazquez, M. P.; Albarracin, V. H.
10.1101/2020.12.21.423370 — genomics — Posted on 2020-12-22
943 Wnt3 expression as a readout of tissue stretching during Hydra regeneration
Ferenc, J.; Papasaikas, P.; Ferralli, J.; Nakamura, Y.; Smallwood, S.; Tsiairis, C. D.
10.1101/2020.12.22.423911 — developmental biology — Posted on 2020-12-22
944 AF10 (MLLT10) prevents somatic cell reprogramming through regulation of H3K79 methylation
Ugurlu-Cimen, D.; Odluyurt, D.; Sevinc, K.; Ozkan-Kucuk, N. E.; Ozcimen, B.; Demirtas, D.; Philpott, M.; Oppermann, U.; Ozlu, N.; Onder, T. T.
10.1101/2020.12.22.423908 — developmental biology — Posted on 2020-12-22
945 Functional analysis of caspase cleavable proteoforms from the Drosophila GSK-3 gene shaggy.
Korona, D.; Nightingale, D.; Fabre, B.; Nelson, M. G.; Fischer, B.; Johnson, G.; Hubbard, S. J.; Lilley, K. S.; Russell, S.
10.1101/2020.12.22.423955 — developmental biology — Posted on 2020-12-22
947 Definition of germ cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate
Fagg, W. S.; Liu, N.; Braunschweig, U.; Chen, X.; Widen, S. G.; Donohue, J. P.; Fair, J. H.; Weirauch, M. T.; Blencowe, B. J.; Garcia-Blanco, M. A.
10.1101/2020.12.22.423880 — molecular biology — Posted on 2020-12-22
950 Wild animal oral microbiomes reflect the history of human antibiotics use
Brealey, J. C.; Leitao, H. G.; Hofstede, T.; Kalthoff, D. C.; Guschanski, K.
10.1101/2020.12.22.423960 — microbiology — Posted on 2020-12-22
951 Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
Hamm, J.; Hinrichsen, F.; Schroder, L.; Mishra, N.; Shima, K.; Walker, A.; Sommer, N.; Klischies, K.; Prasse, D.; Zimmermann, J.; Kaiser, S.; Bordoni, D.; Fazio, A.; Laue, G.; Tremaroli, V.; Basic, M.; Hasler, R.; Schmitz, R. A.; Krautwald, S.; Wolf, A.; Stecher, B.; Schmitt-Kopplin, P.; Kaleta, C.; Rupp, J.; Backhed, F.; Rosenstiel, P.; Sommer, F.
10.1101/2020.12.22.423953 — immunology — Posted on 2020-12-22
952 Fate trajectories of CD8+ T cells in chronic LCMV infection
Cerletti, D.; Sandu, I.; Gupta, R.; Oxenius, A.; Claassen, M.
10.1101/2020.12.22.423929 — immunology — Posted on 2020-12-22
953 Genome-wide reversal of glial and neurovascular cell transcriptomic aging signatures by GLP-1R agonism
Li, Z.; Chen, X.; Vong, J. S. L.; Zhao, L.; Huang, J.; Yan, L. Y. C.; IP, B.; Wing, Y. K.; Lai, H.-M.; Mok, V. C. T.; Ko, H.
10.1101/2020.12.21.423879 — neuroscience — Posted on 2020-12-22
954 Analysis methods for measuring fNIRS responses generated by a block-design paradigm
Luke, R.; Larson, E.; Shader, M. J.; Innes-Brown, H.; Van Yper, L.; Lee, A. K.; Sowman, P. F.; McAlpine, D.
10.1101/2020.12.22.423886 — neuroscience — Posted on 2020-12-22
955 Multiple overlapping dynamic patterns of the visual sensory network in schizophrenia
Sendi, M. S. E.; Pearlson, G. D.; Mathalon, D. H.; Ford, J. M.; Preda, A.; van Erp, T. G. M.; Calhoun, V. D.
10.1101/2020.12.21.423535 — neuroscience — Posted on 2020-12-22
957 Inclusion of maintenance energy improves the intracellular flux predictions of CHO
Diana Szeliova, D.; Stor, J.; Thiel, I.; Weinguny, M.; Hanscho, M.; Lhota, G.; Borth, N.; Zanghellini, J.; Ruckerbauer, D. E.; Rocha, I.
10.1101/2020.12.21.423738 — systems biology — Posted on 2020-12-22
958 Multicohort Analysis of Publicly-available Monocyte Expression Data Identifies Gene Signatures to Accurately Monitor Subset-specific Changes in Human Diseases
Vallania, F.; Zisman, L.; Macaubas, C.; Hung, S.-C.; Rajasekaran, N.; Mason, S.; Graf, J.; Nakamura, M.; Mellins, E.; Khatri, P.
10.1101/2020.12.21.423397 — systems biology — Posted on 2020-12-22
959 Systematic detection of functional proteoform groups from bottom-up proteomic datasets
Bludau, I.; Frank, M.; Doerig, C.; Cai, Y.; Heusel, M.; Rosenberger, G.; Picotti, P.; Collins, B. C.; Roest, H.; Aebersold, R.
10.1101/2020.12.22.423928 — systems biology — Posted on 2020-12-22
961 Live monitoring of ROS-induced cytosolic redox changes with roGFP2-based sensors in plants
Ugalde, J. M.; Fecker, L.; Schwarzlaender, M.; Mueller-Schuessele, S. J.; Meyer, A. J.
10.1101/2020.12.21.423768 — plant biology — Posted on 2020-12-22
962 Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity
Sun, X.; Lapin, D.; Feehan, J. M.; Stolze, S. C.; Kramer, K.; Dongus, J. A.; Rzemieniewski, J.; Blanvillain-Baufume, S.; Harzen, A.; Bautor, J.; Derbyshire, P.; Menke, F. L. H.; Finkemeier, I.; Nakagami, H.; Jones, J. D. G.; Parker, J. E.
10.1101/2020.12.21.423810 — plant biology — Posted on 2020-12-22
963 The p-coumaroyl arabinoxylan transferase HvAT10 underlies natural variation in whole-grain cell wall phenolic acids in cultivated barley
Houston, K.; Learmonth, A.; Hassan, A. S.; Lahnstein, J.; Looseley, M.; Little, A.; Waugh, R.; Burton, R. A.; Halpin, C.
10.1101/2020.12.21.423816 — plant biology — Posted on 2020-12-22
964 A derived ZW chromosome system in Amborella trichopoda, the sister species to all other extant flowering plants
Kafer, J.; Bewick, A.; Andres-Robin, A.; Lapetoule, G.; Harkess, A.; Caius, J.; Fogliani, B.; Gateble, G.; Ralph, P.; dePamphilis, C. W.; Picard, F.; Scutt, C. P.; Leebens-Mack, J.; Marais, G. A.
10.1101/2020.12.21.423833 — plant biology — Posted on 2020-12-22
968 PKA drives paracrine crisis and WNT4-dependent testis tumor in Carney complex
Djari, C.; Sahut-Barnola, I.; Septier, A.; Plotton, I.; Montanier, N.; Dufour, D.; Levasseur, A.; Wilmouth, J.; Pointud, J.-C.; Faucz, F.; Kamilaris, C.; Lopez, A.-G.; Guillou, F.; Swain, A.; Vainio, S. J.; Tauveron, I.; Val, P.; Lefebvre, H.; Stratakis, C.; Martinez, A.; Lefrancois-Martinez, A. M.
10.1101/2020.12.21.423735 — pathology — Posted on 2020-12-22
969 A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data
Douglass, E. F.; Allaway, R. J.; Szalai, B.; Wang, W.; Tian, T.; Fernandez, A.; Realubit, R.; Karan, C.; Zheng, S.; Pessia, A.; Tanoli, Z.; Jafari, M.; Wan, F.; Li, S.; Xiong, Y.; Duran-Frigola, M.; Bertoni, M.; Badia-i-Mompel, P.; Mateo, L.; Guitart-Pla, O.; Chung, V.; DREAM CTD-squared Pancancer Drug Activity Challenge Consortium, ; Tang, J.; Zeng, J.; Aloy, P.; Saez-Rodriguez, J.; Guinney, J.; Gerhard, D. S.; Califano, A.
10.1101/2020.12.21.423514 — cancer biology — Posted on 2020-12-22
970 Recapitulating tumor microenvironment using preclinical 3D tissueoids model for accelerating cancer research and drug screening
Baru, A.; Mazumder, S.; Kundu, P. K.; Sharma, S.; Das Purakayastha, B. P.; Khan, S.; gupta, R.; Arora, N. M.
10.1101/2020.12.21.423825 — cancer biology — Posted on 2020-12-22
971 APOBEC3B expression generates an immunogenic model of Kras mutant lung cancer
de Carne Trecesson, S.; Boumelha, J.; Law, E.; Romero-Clavijo, P.; Mugarza, E.; Coelho, M.; Moore, C.; Rana, S.; Caswell, D.; Murillo, M.; Hancock, D.; Argyris, P.; Brown, W.; Durfee, C.; Larson, L.; Vogel, R.; Alejandro Suarez-Bonnet, A.; Priestnall, S.; East, P.; Ross, S.; Molina-Arcas, M.; Swanton, C.; Harris, R.; Downward, J.
10.1101/2020.12.22.423126 — cancer biology — Posted on 2020-12-22
972 Arginine Methylation Regulates Ribosome CAR Function
Scopino, K.; Dalgarno, C.; Nachmannoff, C.; Krizanc, D.; Thayer, K. M.; Weir, M. P.
10.1101/2020.12.21.423835 — biophysics — Posted on 2020-12-22
973 Oligomerization of the Human Adenosine A2A Receptor Is Driven by the Intrinsically Disordered C-Terminus
Nguyen, K. D.; Vigers, M.; Sefah, E.; Seppala, S.; Hoover, J. P.; Schonenbach, N. S.; Mertz, B.; O'Malley, M. A.; Han, S.
10.1101/2020.12.21.423144 — biophysics — Posted on 2020-12-22
975 Single Layers of Attention Suffice to Predict Protein Contacts
Bhattacharya, N.; Thomas, N.; Rao, R.; Daupras, J.; Koo, P.; Baker, D.; Song, Y. S.; Ovchinnikov, S.
10.1101/2020.12.21.423882 — bioinformatics — Posted on 2020-12-22
982 Liver Electrical Impedance Tomography for Early Identification of Fatty Infiltrate in Obesity
Chang, C.-C.; Huang, Z.-Y.; Shih, S.-F.; Luo, Y.; Ko, A.; Cui, Q.; Cavallero, S.; Das, S.; Thames, G.; Bui, A.; Jacobs, J. P.; Pajukanta, P.; Wu, H.; Tai, Y.-C.; Li, Z.; Hsiai, T.
10.1101/2020.12.21.423854 — bioengineering — Posted on 2020-12-22
986 Current population structure and pathogenicity patterns of Ascochyta rabiei in Australia
Bar, I.; Thanjavur Sambasivam, P.; Davidson, J.; Farfan Caceres, L. M.; Lee, R. C.; Hobson, K.; Moore, K.; Ford, R.
10.1101/2020.12.21.423875 — genomics — Posted on 2020-12-22
988 Untangling structural factors and evolutionary drivers in nascent polyploids
Ferreira de Carvalho, J.; Stoeckel, S.; Eber, F.; Lode-Taburel, M.; Gilet, M.-M.; Trotoux, G.; Morice, J.; Falentin, C.; Chevre, A.-M.; Rousseau-Gueutin, M.
10.1101/2020.12.21.423805 — evolutionary biology — Posted on 2020-12-22
989 Pastures and Climate Extremes: Impacts of warming and drought on the productivity and resilience of key pasture species in a field experiment
Churchill, A. C.; Zhang, H.; Fuller, K. J.; Amiji, B.; Anderson, I. C.; Barton, C. V. M.; Carrillo, Y.; Catunda, K. L. M.; Chandregowda, M. H.; Igwenagu, C.; Jacob, V.; Kim, G. W. C.; Macdonald, C. A.; Medlyn, B. E.; Moore, B. D.; Pendall, E.; Plett, J. M.; Post, A. K.; Powell, J. R.; Tissue, D. T.; Tjoelker, M. G.; Power, S. A.
10.1101/2020.12.21.423155 — ecology — Posted on 2020-12-22
992 osr1 maintains renal progenitors and regulates podocyte development by promoting wnt2ba through antagonism of hand2
Drummond, B. E.; Chambers, B. E.; Wesselman, H. M.; Ulrich, M. N.; Gerlach, G. F.; Kroeger, P. T.; Leshchiner, I.; Goessling, W.; Wingert, R. A.
10.1101/2020.12.21.423845 — developmental biology — Posted on 2020-12-22
994 Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially affect symptoms in an advanced murine Graft-versus-Host-Disease model
Madel, R. J.; Börger, V.; Dittrich, R.; Bremer, M.; Tertel, T.; Ngo Thi Phuong, N.; Babo, H. A.; Kordelas, L.; Buer, J.; Horn, P. A.; Westendorf, A. M.; Brandau, S.; Kirschning, C. J.; Giebel, B.
10.1101/2020.12.21.423658 — cell biology — Posted on 2020-12-22
995 The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles
Gomes Pereira, S.; Sousa, A. L.; Nabais, C.; Paixão, T.; Holmes, A. J.; Schorb, M.; Goshima, G.; Tranfield, E. M.; Becker, J. D.; Bettencourt-Dias, M.
10.1101/2020.12.21.423647 — cell biology — Posted on 2020-12-22
996 Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model
Clarke, M. F.; Reinitz, F.; Chen, E.; Nicolis di Robilant, B.; Chuluun, B.; Antony, J.; Jones, R. C.; Gubbi, N.; Kolluru, S. S.; Qian, D.; Piltti, K.; Monje, M.; Anderson, A.; Heller, H. C.; Quake, S. R.
10.1101/2020.12.21.383059 — molecular biology — Posted on 2020-12-22
997 The Utilization of Advance Telemetry to Investigate Important Physiological Parameters Including Electroencephalography in Cynomolgus Macaques Following Aerosol Challenge with Eastern Equine Encephalitis Virus
Trefry, J. C.; Rossi, F. D.; Accardi, M.; Dorsey, B.; Sprague, T. R.; Wollen-Roberts, S. E.; Shamblin, J. D.; Kimmel, A. E.; Glass, P. J.; Miller, L.; Cardile, A. P.; Smith, D. R.; Bavari, S.; Authier, S.; Pratt, W. D.; Pitt, M. L.; Nasar, F.
10.1101/2020.12.21.423826 — microbiology — Posted on 2020-12-22
998 A novel antigenic site spanning domains I and III of the Zika virus envelope glycoprotein is the target of strongly neutralizing human monoclonal antibodies
Graham, S.; Tu, H. A.; McElvany, B. D.; Graham, N. R.; Grinyo, A.; Davidson, E.; Doranz, B. J.; Diehl, S. A.; de Silva, A. M.; Markmann, A. J.
10.1101/2020.12.21.423896 — immunology — Posted on 2020-12-22
1006 Repurposing Nintedanib for Pathological Cardiac Remodeling and Dysfunction
Umbarkar, P.; Singh, A. P.; Tousif, S.; Zhang, Q.; Sethu, P.; Lal, H.
10.1101/2020.12.21.423817 — pathology — Posted on 2020-12-22
1007 Design of novel CV-N variants: Modulation of binding dynamics through distal mutations
Kazan, I. C.; Sharma, P.; Bobkov, A. A.; Fromme, R.; Ghirlanda, G.; Ozkan, S. B.
10.1101/2020.12.21.423842 — biophysics — Posted on 2020-12-22
1017 ISSRseq: an extensible, low-cost, and efficient method for reduced representation sequencing
Sinn, B. T.; Simon, S. J.; Santee, M. V.; DiFazio, S. P.; Fama, N. M.; Barrett, C. F.
10.1101/2020.12.21.423774 — genomics — Posted on 2020-12-22
1022 Restoration ecologists might not get what they want: Global change shifts trade-offs among ecosystem functions
Fiedler, S.; Monteiro, J. A. F.; Hulvey, K. B.; Standish, R. J.; Perring, M. P.; Tietjen, B.
10.1101/2020.12.21.423790 — ecology — Posted on 2020-12-22
1024 CTCF is a Barrier for Totipotent-like Reprogramming
Olbrich, T.; Vega-Sendino, M.; Tillo, D.; Wu, W.; Zolnerowich, N.; Tran, A. D.; Domingo, C. N.; Franco, M.; Markiewicz Potoczny, M.; Pegoraro, G.; Fitzgerald, P.; Kruhlak, M.; Lazzerini, E.; Nora, E.; Nussenzweig, A.; Ruiz Macias, S.
10.1101/2020.12.20.423692 — developmental biology — Posted on 2020-12-22
1027 Coordinated Changes in Gene Expression Kinetics Underlie both Mouse and Human Erythroid Maturation
Barile, M.; Imaz-Rosshandler, I.; Inzani, I.; Ghazanfar, S.; Nichols, J.; Marioni, J. C.; Guibentif, C.; Gottgens, B.
10.1101/2020.12.21.423773 — developmental biology — Posted on 2020-12-22
1028 High-resolution Cell Atlas of Pig Lung and Online Platform Exploring for Lung Single Cell
Zhang, L.; Zhu, J.; Wang, H.; Xia, J.; Liu, P.; Chen, F.; Jiang, H.; Wu, W.; Luo, L.; Chen, D.; Zhang, X.
10.1101/2020.12.20.423716 — cell biology — Posted on 2020-12-22
1029 STING Nuclear Partners Contribute to Innate Immune Signalling Responses
Dixon, C. R.; Malik, P.; de las Heras, J. I.; Saiz-Ros, N.; de Lima Alves, F.; Tingey, M.; Gaunt, E. R.; Richardson, C.; Kelly, D.; Goldberg, M. W.; Towers, G. J.; Yang, W.; Rappsilber, J.; Digard, P.; Schirmer, E. C.
10.1101/2020.12.21.423744 — immunology — Posted on 2020-12-22
1030 CLEC-2 promotes inflammatory peritoneal macrophage emigration to draining lymph nodes during endotoxemia
Bourne, J. H.; Beristain Covarrubias, N.; zuidscherwoude, M.; Campos, J.; Di, Y.; Garlick, E.; Colicchia, M.; Terry, L. V.; Thomas, S. G.; Brill, A.; Barry, J.; Watson, S. P.; Rayes, J.
10.1101/2020.12.21.423770 — immunology — Posted on 2020-12-22
1033 Bursting firing in ventromedial hypothalamic neurons exerts dual control of anxiety-like behavior and energy expenditure
Shao, J.; Gao, D.; Liu, Y.; Chen, S.; Liu, N.; Zhang, L.; Zhou, X.; Xiao, Q.; Wang, L.; Hu, H.; Yang, F.
10.1101/2020.12.20.423695 — neuroscience — Posted on 2020-12-22
1039 An Introduction to Thermodynamic Integration and Application to Dynamic Causal Models
Aponte, E.; Yao, Y.; Raman, S.; Frassle, S.; Heinzle, J.; Penny, W.; Stephan, K.
10.1101/2020.12.21.423807 — neuroscience — Posted on 2020-12-22
1042 Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism
Pospori, C.; Grey, W.; Gonzalez-Anton, S.; Gibson, S. V.; Georgiou, C.; Birch, F.; Stevens, G.; Williams, T.; Khorshed, R.; Haltalli, M. L. R.; Skoufou-Papoutsaki, M.-N.; Sloan, K.; Encabo, H. H.; Hopkins, J.; Christodoulidou, C.; Stampoulis, D.; Hearn-Yates, F.; Gribben, J.; Stauss, H. J.; Chakraverty, R.; Bonnet, D.; Lo Celso, C. L.
10.1101/2020.12.21.414649 — cancer biology — Posted on 2020-12-22
1044 hRUV: Hierarchical approach to removal of unwanted variation for large-scale metabolomics data
Kim, T.; Tang, O.; Vernon, S. T.; Kott, K. A.; Koay, Y. C.; Park, J.; James, D.; Speed, T. P.; Yang, P.; O'Sullivan, J. F.; Figtree, G. A.; Yang, J. Y. H.
10.1101/2020.12.21.423723 — bioinformatics — Posted on 2020-12-22
1045 Sexual conflict drives micro- and macroevolution of sexual dimorphism in immunity
Bagchi, B.; Corbel, Q.; Khan, I.; Payne, E.; Banerji, D.; Liljestrand-Ronn, J.; Martinossi-Allibert, I.; Baur, J.; Sayadi, A.; Immonen, E.; Arnqvist, G.; Soderhall, I.; Berger, D.
10.1101/2020.12.20.423717 — evolutionary biology — Posted on 2020-12-22
1049 Stem cell derived astrocytes with POLG mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neurons
Liang, K. X.; Kianian, A.; Chen, A.; Kristiansen, C. K.; Hong, Y.; Furriol, J.; Hoyland, L. E.; Ziegler, M.; Krakenes, T.; Tzoulis, C.; Sullivan, G. J.; Bindoff, L. A.
10.1101/2020.12.20.423652 — neuroscience — Posted on 2020-12-22
1057 The ENIGMA Toolbox: Cross-disorder integration and multiscale neural contextualization of multisite neuroimaging datasets
Lariviere, S.; Paquola, C.; Park, B.-y.; Royer, J.; Wang, Y.; Benkarim, O.; Vos de Wael, R.; Valk, S. L.; Thomopoulos, S. I.; Kirschner, M.; ENIGMA Consortium, ; Sisodiya, S.; McDonald, C.; Thompson, P. M.; Bernhardt, B.
10.1101/2020.12.21.423838 — neuroscience — Posted on 2020-12-22
1061 Hidden genomic features of an invasivemalaria vector, Anopheles stephensi
Chakraborty, M.; Ramaiah, A.; Adolfi, A.; Halas, P.; Kaduskar, B.; Ngo, L. T.; Jayaprasad, S.; Paul, K.; Whadgar, S.; Srinivasan, S.; Subramani, S.; Bier, E.; James, A.; Emerson, J. J.
10.1101/2020.05.24.113019 — genomics — Posted on 2020-12-22
1064 Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane
Zhao, L.; Chen, F.; Quitt, O.; Festag, M.; Ringelhan, M.; Wisskirchen, K.; Hasreiter, J.; Yakovleva, L.; Sureau, C.; Bohne, F.; Aichler, M.; Bruss, V.; Shevtsov, M.; van de Klundert, M. A.; Momburg, F.; Möhl, B. S.; Protzer, U.
10.1101/2020.12.21.423802 — microbiology — Posted on 2020-12-22
1066 Immune-Based Prediction of COVID-19 Severity and Chronicity Decoded Using Machine Learning
Patterson, B.; Guevara-Coto, J.; Yogendra, R.; Francisco, E. B.; long, e.; Pise, A.; Rodrigues, H.; Parikh, P.; Mora, J.; Mora-Rodriguez, R. A.
10.1101/2020.12.16.423122 — immunology — Posted on 2020-12-22
1067 Synaptic dysfunction caused by truncated tau is associated with hyperpolarization-activated cyclic nucleotide-gated channelopathy
Goniotaki, D.; Tamagnini, F.; Biasetti, L.; Rumpf, S. L.; Fennell, K.; Pollack, S.; Ukwesa, S.; Sun, H.; Serpell, L.; Noble, W.; Staras, K.; Hanger, D.
10.1101/2020.11.08.369488 — neuroscience — Posted on 2020-12-22
1068 MCSS-based Predictions of Binding Mode and Selectivity of Nucleotide Ligands
Gonzalez-Aleman, R.; Chevrollier, N.; Simoes, M.; Montero-Cabrera, L.; Leclerc, F.
10.1101/622068 — bioinformatics — Posted on 2020-12-22
1069 Fatty Acyl Availability Modulates Cardiolipin Composition and Alters Mitochondrial Function in HeLa Cells
Oemer, G.; Edenhofer, M.-L.; Lackner, K.; Leman, G.; Koch, J.; Lindner, H. H.; Dubrac, S.; Zschocke, J.; Keller, M. A.
10.1101/2020.02.10.937433 — biochemistry — Posted on 2020-12-22
1071 Tumor MHCII immunity requires in situ antigen presentation by cancer-associated fibroblasts.
Kerdidani, D.; Aerakis, E.; Verrou, K.-M.; Stamoulis, P.; Goudevenou, K.; Prados, A.; Tzaferis, C.; Vamvakaris, I.; Kaniaris, E.; Vachlas, K.; Sepsas, E.; Potaris, K.; Koutsopoulos, A.; Tsoumakidou, M.
10.1101/2020.03.24.005355 — immunology — Posted on 2020-12-22
1074 A physical theory of larval Drosophila behaviour
Loveless, J.; Garner, A.; Issa, A. R.; Roberts, R. J. V.; Webb, B.; Prieto-Godino, L. L.; Ohyama, T.; Alonso, C.
10.1101/2020.08.25.266163 — biophysics — Posted on 2020-12-22
1075 Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope tag insertion
Tamura-Sakaguchi, R.; Aruga, R.; Hirose, M.; Ekimoto, T.; Miyake, T.; Hizukuri, Y.; Oi, R.; Kaneko, M. K.; Kato, Y.; Akiyama, Y.; Ikeguchi, M.; Iwasaki, K.; Nogi, T.
10.1101/2020.10.06.325969 — biophysics — Posted on 2020-12-22
1080 The ENIGMA Toolbox: Cross-disorder integration and multiscale neural contextualization of multisite neuroimaging datasets
Lariviere, S.; Paquola, C.; Park, B.-y.; Royer, J.; Wang, Y.; Benkarim, O.; Vos de Wael, R.; Valk, S. L.; Thomopoulos, S. I.; Kirschner, M.; ENIGMA Consortium, ; Sisodiya, S.; McDonald, C.; Thompson, P. M.; Bernhardt, B.
10.1101/2020.12.21.423838 — neuroscience — Posted on 2020-12-22
1082 A new genome-wide method to identify genes with bimodal gene expression
Justino, J. R.; dos Reis, C. F.; Fonseca, A. F.; de Souza, S. J.; Stransky, B.
10.1101/2020.12.21.423759 — genomics — Posted on 2020-12-21
1083 SNPnexus COVID: Facilitating the analysis of COVID-19 host genetics
Oscanoa, J.; Sivapalan, L.; Abdollahyan, M.; Gadaleta, E.; Chelala, C.
10.1101/2020.12.18.423439 — genomics — Posted on 2020-12-21
1084 Dog color patterns explained by modular promoters of ancient canid origin
Bannasch, D.; Kaelin, C. B.; Letko, A.; Loechel, R.; Hug, P.; Jagannathan, V.; Henkel, J.; Roosje, P.; Hytonen, M.; Lohi, H.; Arumilli, M.; DoGA consortium, ; Minor, K.; Mickelson, J.; Drogemuller, C.; Barsh, G.; Leeb, T.
10.1101/2020.12.21.423812 — genetics — Posted on 2020-12-21
1085 N-glycolylneuraminic acid binding of avian H7 influenza A viruses
Spruit, C. M.; Zhu, X.; Broszeit, F.; Han, A. X.; van der Woude, R.; Bouwman, K. M.; Luu, M. M.; Russell, C. A.; Wilson, I. A.; Boons, G.-J.; de Vries, R.
10.1101/2020.12.21.423767 — molecular biology — Posted on 2020-12-21
1087 Evaluation of a polymeric composite bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect
Beenken, K.; Campbell, M.; Ramirez, A.; Alghazali, K.; Walker, C.; Jackson, B.; Griffin, C.; King, W.; Bourdo, S.; Rifkin, R.; Hecht, S.; Meeker, D.; Anderson, D.; Biris, A.; Smeltzer, M.
10.1101/2020.12.21.423753 — microbiology — Posted on 2020-12-21
1089 Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion ΔH69/V70
Kemp, S.; Harvey, W.; Datir, R.; Collier, D.; Ferreira, I.; Carabelii, A.; Robertson, D. L.; Gupta, R. K.
10.1101/2020.12.14.422555 — microbiology — Posted on 2020-12-21
1090 What we can and what we cannot see with extracellular multielectrodes
Chintaluri, C.; Bejtka, M.; Sredniawa, W.; Czerwinski, M.; Dzik, J. M.; Jedrzejewska-Szmek, J.; Kondrakiewicz, K.; Kublik, E.; Wojcik, D. K.
10.1101/2020.12.21.423760 — neuroscience — Posted on 2020-12-21
1092 Effects of Transport and Altitude on Hormones and Oxidative Stress Parameters in Sheep
TOZLU CELIK, H.; ASLAN, F. A.; US ALTAY, D.; KAHVECI, M. E.; KONANC, K.; NOYAN, T.; AYHAN, S.; Hilal TOZLU CELIK, Fatih Ahmet ASLAN, Diler US ALTAY, Metehan Eser KAHVECI, Kalbiye,
10.1101/2020.12.21.423758 — zoology — Posted on 2020-12-21
1093 Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations
Miersch, S.; Li, Z.; Saberianfar, R.; Ustav, M.; Case, J. B.; Blazer, L.; Chen, C.; Ye, W.; Pavlenco, A.; Gorelik, M.; Garcia Perez, J.; Subramania, S.; Singh, S.; Ploder, L.; Ganaie, S.; Chen, R.; Leung, D.; Pandolfi, P. P.; Novelli, G.; Matusali, G.; Colavita, F.; Copabianchi, M. R.; Jain, S.; Gupta, J. B.; Amarasinghe, G. K.; Diamond, M. S.; Rini, J.; Sidhu, S.
10.1101/2020.10.31.362848 — synthetic biology — Posted on 2020-12-21
1094 Institutionalizing an Evidence-Based Practice in a Selected Government Agency in Nigeria
Nwaichi, E. O.; Chidebe, I.; Osuoha, J.; Chimezie, E.; Mbaoji, C.; Ifeanyi-Obi, C.; Ugwoha, E.; Odogwu, B.; Okengwu, U.; Olua, V.; Oghenekaro, L.; Agbagwa, O.; Frank-Peterside, N.; Ozah, M. A.; Raphael, C.; Ugiomoh, I.; Nwoha, P.; Akpoji, B.
10.1101/2020.12.21.423750 — scientific communication and education — Posted on 2020-12-21
1097 Functional Aspects of the Eustachian Tube by Means of 3D-Modeling
Schuon, R. A.; Schwarzensteiner, J.; Paasche, G.; Lenarz, T.; John, S.
10.1101/2020.12.21.423756 — physiology — Posted on 2020-12-21
1098 Africanized honeybees in Colombia exhibit high prevalence but low level of infestation of Varroa mites and low prevalence of pathogenic viruses
Tibata, V. M.; Sanchez, A.; Young-Palmer, E.; Junca, H.; Solarte, V. M.; Madella, S.; Ariza, F.; Figueroa, J.; Corona, M.
10.1101/2020.12.21.423754 — pathology — Posted on 2020-12-21
1099 EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape.
Ungerleider, N.; Bullard, W.; Kara, M.; Wang, X.; Roberts, C.; Renne, R.; Tibbetts, S.; Flemington, E. K.
10.1101/2020.12.21.423766 — cancer biology — Posted on 2020-12-21
1100 Fusobacterium nucleatum facilitates cetuximab resistance in colorectal cancer via the PI3K/AKT and JAK/STAT3 pathways
Yuan, X.; Han, H.; Li, Y.; Qin, W.; Wang, L.; Yin, H.; Su, B.; Yan Li, Wan Qin, Lu Wang, Han Yin, Beibei Su, and Xianglin Yuan,
10.1101/2020.12.21.423755 — cancer biology — Posted on 2020-12-21
1102 The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
Cubuk, J.; Alston, J. J.; Incicco, J. J.; Singh, S.; Stuchell-Brereton, M. D.; Ward, M. D.; Zimmerman, M. I.; Vithani, N.; Griffith, D.; Wagoner, J. A.; Bowman, G. R.; Hall, K. B.; Soranno, A.; Holehouse, A. S.
10.1101/2020.06.17.158121 — biophysics — Posted on 2020-12-21
1105 Iliski, a software for robust calculation of transfer functions
Aydin, A.-K.; Haselden, W. D.; Dang, J.; Drew, P. J.; charpak, s.; Boido, D.
10.1101/2020.12.21.423764 — bioinformatics — Posted on 2020-12-21
1106 Principled simulation of agent-based models in epidemiology
Wu, S. L.; Dolgert, A. J.; Lewnard, J. A.; Marshall, J. M.; Smith, D. L.
10.1101/2020.12.21.423765 — ecology — Posted on 2020-12-21
1108 Gene Networks and Pathways for Plasma Lipid Traits via Multi-tissue Multi-omics Systems Analysis
Blencowe, M.; Ahn, I. S.; Saleem, Z.; Luk, H.; Cely, I.; Mäkinen, V.-P.; Zhao, Y.; Yang, X.
10.1101/2020.02.28.970368 — systems biology — Posted on 2020-12-21
1111 Quantitative Control of Noise in Mammalian Gene Expression by Dynamic Histone Regulations
Tan, D.; Chen, R.; Mo, Y.; Xu, W.; Lu, X.; He, H.; Gu, S.; Jiang, F.; Fan, W.; Wang, Y.; Chen, X.; Huang, W.
10.1101/2020.12.20.423693 — molecular biology — Posted on 2020-12-21
1114 The combination of Bromelain and Acetylcysteine (BromAc) synergistically inactivates SARS-CoV-2
Akhter, J.; Queromes, G.; Pillai, K.; Kepenekian, V.; Badar, S.; Mekkawy, A.; Frobert, E.; Valle, S.; Morris, D. L.
10.1101/2020.09.07.286906 — microbiology — Posted on 2020-12-21
1115 Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Mayekar, M. K.; Caswell, D. R.; Vokes, N. I.; Law, E. K.; Wu, W.; Hill, W.; Gronroos, E.; Rowan, A.; Al Bakir, M.; McCoach, C. E.; Blakely, C. M.; Temiz, N. A.; Nagano, A.; Kerr, D. L.; Rotow, J. K.; Haderk, F.; Dietzen, M.; Ruiz, C. M.; Almeida, B.; Cech, L.; Gini, B.; Przewrocka, J.; Moore, C.; Murillo, M.; Bakker, B.; Rule, B.; Durfee, C.; Nanjo, S.; Tan, L.; Larson, L. K.; Argyris, P. P.; Brown, W. L.; Yu, J.; Gomez, C.; Gui, P.; Vogel, R. I.; Yu, E. A.; Thomas, N. J.; Venkatesan, S.; Hobor, S.; Chew, S. K.; Kanu, N.; McGranahan, N.; Van Allen, E. M.; Downward, J.; Harris, R. S.; Bivona, T
10.1101/2020.12.18.423280 — cancer biology — Posted on 2020-12-21
1118 Fitting side-chain NMR relaxation data using molecular simulations
Kümmerer, F.; Orioli, S.; Harding-Larsen, D.; Hoffmann, F.; Gavrilov, Y.; Teilum, K.; Lindorff-Larsen, K.
10.1101/2020.08.18.256024 — biophysics — Posted on 2020-12-21
1125 Sedimentary ancient DNA shows terrestrial plant richness continuously increased over the Holocene in northern Fennoscandia
Rijal, D. P.; Heintzman, P. D.; Lammers, Y.; Yoccoz, N. G.; Lorberau, K. E.; Pitelkova, I.; Goslar, T.; Murguzur, F. J. A.; Salonen, J. S.; Helmens, K. F.; Bakke, J.; Edwards, M. E.; Alm, T.; Brathen, K. A.; Brown, A. G.; Alsos, I. G.
10.1101/2020.11.16.384065 — ecology — Posted on 2020-12-21
1126 longfin causes cis-ectopic expression of the kcnh2a ether-a-go-go K+ channel to autonomously prolong fin outgrowth
Stewart, S.; Le Bleu, H. K.; Yette, G. A.; Henner, A. L.; Robbins, A. E.; Braunstein, J. A.; Stankunas, K.
10.1101/790329 — developmental biology — Posted on 2020-12-21
1127 Temporal Shifts in Antibiotic Resistance Elements Govern Virus-Pathogen Conflicts
LeGault, K.; Hays, S. G.; Angermeyer, A.; McKitterick, A. C.; Johura, F.-t.; Sultana, M.; Alam, M.; Seed, K. D.
10.1101/2020.12.16.423150 — microbiology — Posted on 2020-12-21
1128 Single mosquito metatranscriptomics identifies vectors, emerging pathogens and reservoirs in one assay
Batson, J.; Kistler, A.; Dudas, G.; Li, L.; Ratnasari, K.; Haas-Stapleton, E.; Logan, P.; Retallack, H.
10.1101/2020.02.10.942854 — microbiology — Posted on 2020-12-21
1129 Multiple pathways to homothallism in closely related yeast lineages in the Basidiomycota
Cabrita, A.; David-Palma, M.; Brito, P. H.; Heitman, J.; Coelho, M. A.; Goncalves, P.
10.1101/2020.09.30.320192 — microbiology — Posted on 2020-12-21
1130 Isoform-level transcriptome Atlas of Macrophage Activation
Vollmers, A. C.; Mekonen, H. E.; Campos, S.; Carpenter, S.; Vollmers, C.
10.1101/2020.12.20.423532 — immunology — Posted on 2020-12-21
1131 Thyroid hormone and thyromimetics inhibit myelin and axonal degeneration and oligodendrocyte loss in EAE
Chaudhary, P.; Marracci, G. H.; Calkins, E.; Pocius, E.; Bensen, A. L.; Scanlan, T. S.; Emery, B.; Bourdette, D. N.
10.1101/2020.12.20.423638 — neuroscience — Posted on 2020-12-21
1133 Information flow, cell types and stereotypy in a full olfactory connectome
Schlegel, P.; Bates, A. S.; Stürner, T.; Jagannathan, S.; Drummond, N.; Hsu, J.; Serratosa Capdevila, L.; Javier, A.; Marin, E. C.; Barth-Maron, A.; Tamimi, I. F. M.; Li, F.; Rubin, G. M.; Plaza, S. M.; Costa, M.; Jefferis, G. S. X. E.
10.1101/2020.12.15.401257 — neuroscience — Posted on 2020-12-21
1134 A scale-dependent measure of system dimensionality
Recanatesi, S.; Bradde, S.; Balasubramanian, V.; Steinmetz, N. A.; Shea-Brown, E.
10.1101/2020.12.19.423618 — neuroscience — Posted on 2020-12-21
1140 In vivo Evaluation and in silico Prediction of the Toxicity of Drepanoalpha Hard capsules
Gbolo Zoawe, B.; Ngbolua Koto-te-Nyiwa, J.-P.; Tshibangu Sha-Tshibey, D.; Memvanga Bondo, P.; Tshilanda Dinangayi, D.; Matondo, A.; Kilembe Thambwe, J.; Lebwaze Masamba, B.; Nachtergael, A.; Mpiana Tshimankinda, P.; Duez, P.
10.1101/2020.12.03.411124 — pharmacology and toxicology — Posted on 2020-12-21
1141 IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.
Laliotis, G. I.; Chavdoula, E.; Paraskevopoulou, M. D.; Kaba, A. D.; La Ferlita, A.; Singh, S.; Anastas, V.; Alaimo, S.; Orlacchio, A.; Nair, K. A.; Taraslia, V.; Vlachos, I.; Capece, M.; Hatzigeorgiou, A.; Palmieri, D. I.; Tsatsanis, C.; Sehgal, L.; Carbone, D. P.; Coppola, V.; Tsichlis, P. N.
10.1101/2020.07.14.195297 — cancer biology — Posted on 2020-12-21
1144 Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning
Koertel, N.; Rueckle, C.; Zhou, Y.; Busch, A.; Sutandy, R. F.; Haase, J.; Pradhan, M.; Musheev, M.; Ostareck, D.; Ostareck-Lederer, A.; Dieterich, C.; Huettelmaier, S.; Niehrs, C.; Dominissini, D.; Koenig, J.; Zarnack, K.
10.1101/2020.12.20.423675 — genomics — Posted on 2020-12-21
1146 Wnt/β-Catenin Signaling Controls Spatio-Temporal Elasticity Patterns in Extracellular Matrix during Hydra Morphogenesis
Veschgini, M.; Petersen, H. O.; Rossetti, F. F.; Abuillan, W.; Kaufmann, S.; Suzuki, R.; Burghammer, M.; Özbek, S.; Holstein, T. W.; Tanaka, M.
10.1101/214718 — developmental biology — Posted on 2020-12-21
1150 Stepwise transmigration cascade of T and B cells through the perivascular channel in lymph node high endothelial venules
Choe, K.; Moon, J.; Lee, S. Y.; Song, E.; Back, J. H.; Song, J.-H.; Hyun, Y.-M.; Uchimura, K.; Kim, P.
10.1101/2020.12.20.423079 — immunology — Posted on 2020-12-21
1151 How hot is the hot zone? Computational modelling clarifies the role of parietal and frontoparietal connectivity during anaesthetic-induced loss of consciousness
Ihalainen, R.; Gosseries, O.; Van de Steen, F.; Raimondo, F.; Panda, R.; Bonhomme, V.; Marinazzo, D.; Bowman, H.; Laureys, S.; Chennu, S.
10.1101/2020.12.19.423595 — neuroscience — Posted on 2020-12-21
1161 End-to-end optimization of prosthetic vision
de Ruyter van Steveninck, J.; Guclu, U.; van Wezel, R. J. A.; van Gerven, M. A. J.
10.1101/2020.12.19.423601 — bioengineering — Posted on 2020-12-21
1162 Mutation Landscape of SARS COV2 in Africa
Nassir, A. A.; Musanabaganwa, C.; Mwikarago, I.
10.1101/2020.12.20.423630 — genomics — Posted on 2020-12-21
1163 Single-cell RNA-sequencing reveals pervasive but highly cell type-specific genetic ancestry effects on the response to viral infection
Randolph, H. E.; Mu, Z.; Fiege, J. K.; Thielen, B. K.; Grenier, J.-C.; Cobb, M. S.; Hussin, J. G.; Li, Y. I.; Langlois, R. A.; Barreiro, L. B.
10.1101/2020.12.21.423830 — genomics — Posted on 2020-12-21
1166 Multi cell line analysis of lysosomal proteomes reveals unique features and novel lysosomal proteins
Akter, F.; Ponnaiyan, S.; Koegler-Mohrbacher, B.; Bleibaum, F.; Damme, M.; Renard, B. Y.; Winter, D.
10.1101/2020.12.21.423747 — molecular biology — Posted on 2020-12-21
1168 Cetylpyridinium chloride-containing mouthwashes reduce in vitro SARS-CoV-2 infectivity
Munoz-Basagoiti, J.; Perez-Zsolt, D.; Leon, R.; Blanc, V.; Gispert, J.; Clotet, B.; Izquierdo-Useros, N.
10.1101/2020.12.21.423779 — microbiology — Posted on 2020-12-21
1170 Eastern Equine Encephalitis Virus Rapidly Infects and Disseminates in the Brain and Spinal Cord of Infected Cynomolgus Macaques Following Aerosol Challenge
Williams, J. A.; Long, S. Y.; Zeng, X.; Kuehl, K.; Babka, A. M.; Davis, N. M.; Liu, J.; Trefry, J. C.; Daye, S.; Facemire, P. R.; Iversen, P. L.; Bavari, S.; Pitt, M. L.; Nasar, F.
10.1101/2020.12.21.423836 — microbiology — Posted on 2020-12-21
1173 Variation in pyrethroid resistance phenotypes in Anopheles darlingi from residual malaria transmission area: warning on suspected resistance built-up in French Guiana.
Vezenegho, S.; Carinci, R.; Issaly, J.; Nguyen, C.; Gaborit, P.; Ferraro, L.; Lacour, G.; Mosnier, E.; Pommier de Santi, V.; Epelboin, Y.; Girod, R.; Briolant, S.; Dusfour, I.
10.1101/2020.12.21.423491 — zoology — Posted on 2020-12-21
1180 A scale-dependent measure of system dimensionality
Recanatesi, S.; Bradde, S.; Balasubramanian, V.; Steinmetz, N. A.; Shea-Brown, E.
10.1101/2020.12.19.423618 — neuroscience — Posted on 2020-12-21
1191 Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma
Voss, W. N.; Hou, Y. J.; Johnson, N. V.; Kim, J. E.; Delidakis, G.; Horton, A. P.; Bartzoka, F.; Paresi, C. J.; Tanno, Y.; Abbasi, S. A.; Pickens, W.; George, K.; Boutz, D. R.; Towers, D. M.; McDaniel, J. R.; Billick, D.; Goike, J.; Rowe, L.; Batra, D.; Pohl, J.; Lee, J.; Gangappa, S.; Sambhara, S.; Gadush, M.; Wang, N.; Person, M. D.; Iverson, B. L.; Gollihar, J. D.; Dye, J.; Herbert, A.; Baric, R. S.; McLellan, J. S.; Georgiou, G.; Lavinder, J. J.; Ippolito, G. C.
10.1101/2020.12.20.423708 — immunology — Posted on 2020-12-21
1193 Connexin-36-expressing Gap Junctions in VTA GABA Neurons Sustain Opiate Dependence
Maal-Bared, G.; Yee, M.; Harding, E. K.; Ghebreselassie, M.; Bergamini, M.; Choy, R.; Kim, E.; Di Vito, S.; Patel, M.; Amirzadeh, M.; Grieder, T. E.; Nagy, J. I.; Bonin, R. P.; van der Kooy, D.
10.1101/2020.12.18.423554 — neuroscience — Posted on 2020-12-21
1194 Interneuron origins in the embryonic porcine medial ganglionic eminence
Casalia, M. L.; Li, T.; Ramsay, H.; ROSS, P. J.; Paredes, M. F.; Baraban, S. C.
10.1101/2020.12.18.423526 — neuroscience — Posted on 2020-12-21
1198 In vitro measurements of protein-protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
Fiedler, S.; Piziorska, M. A.; Denninger, V.; Morgunov, A. S.; Ilsley, A.; Malik, A. Y.; Schneider, M. M.; Devenish, S. R. A.; Meisl, G.; Aguzzi, A.; Fiegler, H.; Knowles, T. P. J.
10.1101/2020.12.20.422820 — biochemistry — Posted on 2020-12-21
1203 Fatty Acid Synthase inhibition prevents palmitoylation of SARS-CoV2 SpikeProtein and improves survival of mice infected with murine hepatitis virus.
Lee, M.; Mekhail, K.; Sugiyama, M.; Latreille, E.; Khosraviani, N.; Wei, K.; Lee, W. L.; Antonescu, C. N.; Fairn, G. D.
10.1101/2020.12.20.423603 — cell biology — Posted on 2020-12-21
1204 Efficient target cleavage by Type V Cas12a effector programmed with split CRISPR RNA
Tkach, R.; Nikitchina, N.; Shebanov, N.; Mekler, V.; Ulashchik, E.; Sharko, O.; Shmanai, V.; Tarassov, I.; Severinov, K.; Entelis, N.; Mazunin, I.
10.1101/2020.12.21.423781 — molecular biology — Posted on 2020-12-21
1206 Methane emission of humans is explained by dietary habits, host genetics, local formate availability and a uniform archaeome
Kumpitsch, C.; Fischmeister, F.; Mahnert, A.; Lackner, S.; Wilding, M.; Sturm, C.; Holasek, S.; Hoegenauer, C.; Berg, I.; Schoepf, V.; Moissl-Eichinger, C.
10.1101/2020.12.21.423794 — microbiology — Posted on 2020-12-21
1207 Truncated denitrifiers dominate the denitrification pathway in tundra soil metagenomes
Pessi, I. S.; Viitamaki, S.; Eronen-Rasimus, E.; Delmont, T. O.; Luoto, M.; Hultman, J.
10.1101/2020.12.21.419267 — microbiology — Posted on 2020-12-21
1209 A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.
Baisa, G.; Rancour, D.; Mansfield, K.; Burns, M.; Martin, L.; Cunha, D.; Fischer, J.; Muecksch, F.; Hatziioannou, T.; Bieniasz, P.; Schomburg, F.; Luke, K.
10.1101/2020.12.20.422693 — immunology — Posted on 2020-12-21
1210 Task specificity in mouse parietal cortex
Lee, J. J.; Krumin, M.; Harris, K. D.; Carandini, M.
10.1101/2020.12.18.423543 — neuroscience — Posted on 2020-12-21
1211 Body size affects immune cell proportions in birds and non-volant mammals, but not bats
Cornelius Ruhs, E.; Becker, D. J.; Oakey, S. J.; Ogunsina, O.; Fenton, M. B.; Simmons, N. B.; Martin, L. B.; Downs, C. J.
10.1101/2020.12.18.423538 — physiology — Posted on 2020-12-21
1212 Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques
Bewley, K. R.; Gooch, K. E. R.; Thomas, K. M.; Longet, S. R.; Wiblin, N.; Hunter, L.; Chan, K.; Brown, P.; Russell, R. A.; Ho, C.; Slack, G.; Humphries, H. E.; Alden, L.; Allen, L.; Aram, M.; Baker, N.; Brunt, E.; Cobb, R.; Fotheringham, S.; Harris, D.; Kennard, C.; Leung, S.; Ryan, K. A.; Tolley, H.; Wand, N.; White, A.; Sibley, L.; Sarfas, C.; Pearson, G.; Rayner, E.; Xue, X.; Lambe, T.; Charlton, S.; Gilbert, S. C.; Sattentau, Q.; Gleeson, F.; Hall, Y.; Funnell, S. G. P.; Sharpe, S.; Salguero, F. J.; Gorringe, A. R.; Carroll, M.
10.1101/2020.12.21.423746 — pathology — Posted on 2020-12-21
1215 DNA sequence-dependent formation of heterochromatin nanodomains
Thorn, G. J.; Clarkson, C. T.; Rademacher, A.; Mamayusupova, H.; Schotta, G.; Rippe, K.; Teif, V. B.
10.1101/2020.12.20.423673 — genomics — Posted on 2020-12-21
1216 Chromosome dynamics and spatial organization during the non-binary cell cycle of a predatory bacterium
Kaljevic, J.; Saaki, T. N. V.; Govers, S. K.; Remy, O.; van Raaphorst, R.; Lamot, T.; Laloux, G.
10.1101/2020.12.21.419010 — microbiology — Posted on 2020-12-21
1217 Inferring brain-wide interactions using data-constrained recurrent neural network models
Perich, M. G.; Arlt, C.; Soares, S.; Young, M. E.; Mosher, C. P.; Minxha, J.; Carter, E.; Rutishauser, U.; Rudebeck, P. H.; Harvey, C. D.; Rajan, K.
10.1101/2020.12.18.423348 — neuroscience — Posted on 2020-12-21
1219 The Hard Limits of Decoding Mental States: The Decodability of fMRI
Jabakhanji, R.; Vigotsky, A. D.; Bielefeld, J.; Huang, L.; Baliki, M. N.; Iannetti, G.; Apkarian, A. V.
10.1101/2020.12.18.423495 — neuroscience — Posted on 2020-12-21
1220 Structural insights into glycine reuptake inhibition
Shahsavar, A.; Stohler, P.; Bourenkov, G.; Zimmermann, I.; Siegrist, M.; Guba, W.; Pinard, E.; Seeger, M. A.; Schneider, T. R.; Dawson, R. J. P.; Nissen, P.
10.1101/2020.12.20.110478 — neuroscience — Posted on 2020-12-21
1222 The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
Guo, Y.; Yu, J.; Wu, Y.; Gong, H.; Kesteven, S.; Iismaa, S. E.; Chan, A.; Holman, S.; Pinto, S.; Pironet, A.; Cox, C.; Vennekens, R.; Graham, R. M.; Feneley, M. P.; Martinac, B.
10.1101/2020.12.21.423727 — physiology — Posted on 2020-12-21
1223 Post-transcriptional gene regulation by the RNA binding protein IGF2BP3 is critical for MLL-AF4 mediated leukemogenesis
Tran, T. M.; Philipp, J.; Bassi, J.; Nibber, N.; Draper, J.; Lin, T.; Palanichamy, J. K.; Jaiswal, A. K.; Silva, O.; Paing, M.; King, J.; Katzman, S.; Sanford, J. R.; Rao, D. S.
10.1101/2020.12.20.423624 — cancer biology — Posted on 2020-12-21
1227 Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance
Yamazaki, C. M.; Yamaguchi, A.; Anami, Y.; Xiong, W.; Otani, Y.; Lee, J.; Ueno, N. T.; Zhang, N.; An, Z.; Tsuchikama, K.
10.1101/2020.12.18.423326 — bioengineering — Posted on 2020-12-21
1228 The Easter Egg Weevil (Pachyrhynchus) genome reveals synteny in Coleoptera across 200 million years of evolution
Van Dam, M. H.; Cabras, A. A.; Henderson, J. B.; Perez Estrada, C.; Omer, A. D.; Dudchenko, O.; Aiden, E. L.; Lam, A. W.
10.1101/2020.12.18.422986 — genomics — Posted on 2020-12-21
1229 Discovery of synthetic lethal and tumor suppressive paralog pairs in the human genome
Parrish, P. C. R.; Thomas, J. D.; Kamlapurkar, S.; Gabel, A.; Bradley, R. K.; Berger, A. H.
10.1101/2020.12.20.423710 — genomics — Posted on 2020-12-21
1230 A versatile toolkit for molecular QTL mapping and meta-analysis at scale
Quick, C.; Guan, L.; Li, Z.; Li, X.; Dey, R.; Liu, Y.; Scott, L.; Lin, X.
10.1101/2020.12.18.423490 — genetics — Posted on 2020-12-21
1232 Downtown Diet: a global meta-analysis of urbanization on consumption patterns of vertebrate predators
Gamez, S.; Potts, A.; Mills, K. L.; Allen, A.; Holman, A.; Randon, P.; Linson, O.; Harris, N. C.
10.1101/2020.12.19.423628 — ecology — Posted on 2020-12-21
1233 Inferring within-flock transmission dynamics of highly pathogenic avian influenza (H5N8) in France, 2020
Vergne, T.; Gubbins, S.; Guinat, C.; Bauzile, B.; Delpont, M.; Chakraborty, D.; Gruson, H.; Roche, B.; Andraud, M.; Paul, M.; Guerin, J.-L.
10.1101/2020.12.21.423436 — ecology — Posted on 2020-12-21
1237 Transcriptional analysis of immune modulatory genes in melanoma treated with PD-1 blockade
Song, H.; Lee, S.; Lee, S.-H.; Kim, M.; Lee, S. Y.; Yoon, S.-S.; Yun, H.; Koh, Y.
10.1101/2020.12.20.397000 — cancer biology — Posted on 2020-12-21
1242 Real time, field-deployable whole genome sequencing of malaria parasites using nanopore technology
Razook, Z.; Mehra, S.; Gilchhrist, B.; Utama, D.; Lautu-Gumal, D.; Fola, A.; Menard, D.; Kazura, J.; Laman, M.; Mueller, I.; Robinson, L.; Bahlo, M.; Barry, A. E.
10.1101/2020.12.17.423341 — genomics — Posted on 2020-12-21
1243 Cerebral μ-opioid and CB1-receptor systems have distinct roles in human feeding behavior
Kantonen, T.; Karjalainen, T.; Pekkarinen, L.; Isojärvi, J.; Kalliokoski, K.; Kaasinen, V.; Hirvonen, J.; Nuutila, P.; Nummenmaa, L.
10.1101/2020.12.17.423284 — neuroscience — Posted on 2020-12-21
1244 Artificial light at night shifts the circadian system but still leads to physiological disruption in a wild bird
Dominoni, D. M.; de Jong, M.; van Oers, K.; O'Shaughnessy, P. J.; Blackburn, G.; Atema, E.; Mateman, C. A.; D'Amelio, P. B.; Trost, L.; Bellingham, M.; Clark, J.; Visser, M.; Helm, B.
10.1101/2020.12.18.423473 — zoology — Posted on 2020-12-20
1248 Rhamnolipids and their 3-(3-hydroxyalkanoyloxy)alkanoic acid precursors activate Arabidopsis innate immunity through two independent mechanisms
Schellenberger, R.; Crouzet, J.; Nickzad, A.; Kutschera, A.; Gerster, T.; Borie, N.; Dawid, C.; Cloutier, M.; Villaume, S.; Dhondt-Cordelier, S.; Hubert, J.; Cordelier, S.; Mazeyrat-Gourbeyre, F.; Schmid, C.; Ongena, M.; Renault, J.-H.; Haudrechy, A.; Hofmann, T.; Baillieul, F.; Clement, C.; Zipfel, C.; Gauthier, C.; Deziel, E.; Ranf, S.; Dorey, S.
10.1101/2020.12.18.423392 — plant biology — Posted on 2020-12-20
1249 The ratio of exhausted to resident infiltrating lymphocytes is prognostic for colorectal cancer patient outcome
Foroutan, M.; Molania, R.; Pfefferle, A.; Behrenbruch, C.; Kallies, A.; Speed, T. P.; Cursons, J.; Huntington, N. D.
10.1101/2020.12.19.423379 — cancer biology — Posted on 2020-12-20
1251 Testosterone signaling through ZIP9 renders melanoma more aggressive in males than in females
Aguirre-Portoles, C.; Payne, R.; Trautz, A.; Foskett, J. K.; Natale, C. A.; Seykora, J. T.; Ridky, T. W.
10.1101/2020.03.12.989160 — cancer biology — Posted on 2020-12-20
1252 Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
Geiger, F.; Papa, G.; Arter, W. E.; Acker, J.; Saar, K. L.; Erkamp, N.; Qi, R.; Bravo, J. P. K.; Strauss, S.; Krainer, G.; Burrone, O. R.; Jungmann, R.; Knowles, T.; Engelke, H.; Borodavka, A.
10.1101/2020.12.18.423429 — biophysics — Posted on 2020-12-20
1254 Molecular insights on CALX-CBD12 inter-domain dynamics from MD simulations, RDCs and SAXS
Degenhardt, M. F. S.; Vitale, P. A. M.; Abiko, L. A.; Zacharias, M.; Sattler, M.; Oliveira, C. L. P.; Kopke Salinas, R.
10.1101/2020.12.18.423531 — biophysics — Posted on 2020-12-20
1255 Amphipathic Bax core dimer forms part of apoptotic pore wall in the mitochondrial membrane
Lv, F.; Qi, F.; Zhang, Z.; Wen, M.; Piai, A.; Du, L.; Zhou, L.; Yang, Y.; Wu, B.; Liu, Z.; Rosario, J. d.; Chou, J. J.; Andrews, D. W.; Lin, J.; OuYang, B.
10.1101/2020.12.18.423546 — biophysics — Posted on 2020-12-20
1258 Structural and biophysical characterization of the tandem substrate-binding domains of the ABC importer GlnPQ
Ploetz, E.; Schuurman-Wolters, G.; Zijlstra, N.; Jager, A.; Griffith, D. A.; Guskov, A.; Gouridis, G.; Poolman, B.; Cordes, T.
10.1101/2020.12.19.423572 — biophysics — Posted on 2020-12-20
1264 FIREcaller: Detecting Frequently Interacting Regions from Hi-C Data
Crowley, C.; Yang, Y.; Qiu, Y.; Hu, B.; Abnousi, A.; Lipinski, J.; Plewczynski, D.; Wu, D.; Won, H.; Ren, B.; Hu, M.; Li, Y.
10.1101/619288 — bioinformatics — Posted on 2020-12-20
1270 Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
Paramasivam, P.; Franke, C.; Stoeter, M.; Hoijer, A.; Bartesaghi, S.; Sabirsh, A.; Lindfors, L.; Yanez Arteta, M.; Dahlen, A.; Bak, A.; Andersson, S.; Kalaidzidis, Y.; Bickle, M.; Zerial, M.
10.1101/2020.12.18.423541 — bioengineering — Posted on 2020-12-20
1271 Development of an optimized and scalable method for isolation of umbilical cord blood-derived small extracellular vesicles for future clinical use
Cardoso, R. M. S.; Rodrigues, S. C.; Gomes, C. F.; Duarte, F. V.; Romao, M.; Leal, E. C.; Freire, P. C.; Neves, R.; Correia, J. S.
10.1101/2020.12.18.423416 — bioengineering — Posted on 2020-12-20
1273 A nucleotide-sensing endonuclease from the Gabija bacterial defense system
Cheng, R.; Huang, F.; Wu, H.; Lu, X.; Yan, Y.; Yu, B.; Wang, X.; Zhu, B.
10.1101/2020.12.18.423425 — biochemistry — Posted on 2020-12-20
1274 Furin cleaves SARS-CoV-2 spike-glycoprotein at S1/S2 and S2'for viral fusion/entry: indirect role for TMPRSS2
Essalmani, R.; Jain, J.; Susan-Resiga, D.; Andreo, U.; Evagelidis, A.; Derbali, R. M.; Huynh, D.; Dallaire, F.; Laporte, M.; Delpal, A.; Sutto-Ortiz, P.; Coutard, B.; Mapa, C.; Wilcoxen, K.; Decroly, E.; Pham, T.; Cohen, E. A.; Seidah, N. G. G.
10.1101/2020.12.18.423106 — biochemistry — Posted on 2020-12-20
1279 Imaging Cuprizone-Induced Mitochondrial Dysfunction
Ray, L. A.; Pacheco, G.; Taraboletti, A.; Konopka, M. C.; Shriver, L. P.
10.1101/2020.12.18.423512 — biochemistry — Posted on 2020-12-20
1280 Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain
Kleizen, B.; van Willigen, M.; Mijnders, M.; Peters, F. M.; Grudniewska, M. K.; Hillenaar, T. M.; Thomas, A. S.; Kooijman, L.; Peters, K. W.; Frizzell, R.; van der Sluijs, P.; Braakman, I.
10.1101/2020.12.19.423590 — biochemistry — Posted on 2020-12-20
1281 Tuning the transglycosylation reaction of a GH11 xylanase by a delicate enhancement of its thumb flexibility
Marneth, K.; van den Elst, H.; Cramer-Blok, A.; Codee, J. D. C.; Overkleeft, H. S.; Aerts, H. M. F. G.; Ubbink, M.; Ben Bdira, F.
10.1101/2020.12.19.423585 — biochemistry — Posted on 2020-12-20
1282 Does parental angling selection affect the behavior or metabolism of brown trout parr?
Prokkola, J. M.; Alioravainen, N.; Mehtatalo, L.; Hyvarinen, P.; Lemopoulos, A.; Metso, S.; Vainikka, A.
10.1101/611293 — animal behavior and cognition — Posted on 2020-12-20
1283 Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity
Hynes, T.; Hrelja, K.; Hathaway, B.; Hounjet, C.; Chernoff, C.; Ebsary, S.; Betts, G.; Russell, B.; Ma, L.; Kaur, S.; Winstanley, C.
10.1101/2020.06.29.179069 — animal behavior and cognition — Posted on 2020-12-20
1286 Emergence and global spread of Listeria monocytogenes main clinical clonal complex
Moura, A.; Lefrancq, N.; Leclercq, A.; Wirth, T.; Borges, V.; Gilpin, B.; Dallman, T. J.; Frey, J.; Franz, E.; Nielsen, E. M.; Thomas, J.; Pightling, A.; Howden, B. P.; Tarr, C. L.; Gerner-Smidt, P.; Cauchemez, S.; Salje, H.; Brisse, S.; Lecuit, M.; Listeria CC1 Study Group,
10.1101/2020.12.18.423387 — genomics — Posted on 2020-12-20
1287 Chitin biosynthesis genes in Diaphorina citri, Asian citrus psyllid
Miller, S.; Shippy, T.; Tamayo, B.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.09.22.309211 — genomics — Posted on 2020-12-20
1288 Placing ancient DNA sequences into reference phylogenies
Martiniano, R.; de Sanctis, B.; Hallast, P.; Durbin, R.
10.1101/2020.12.19.423614 — genomics — Posted on 2020-12-20
1293 A higher burden of multiple sclerosis genetic risk confers an earlier onset
Misicka, E.; Davis, M.; Kim, W.; Brugger, S. W.; Beales, J.; Loomis, S.; Bronson, P. G.; Briggs, F. B. S.
10.1101/2020.12.18.423477 — genetics — Posted on 2020-12-21
1296 The plot thickens: haploid and triploid-like thalli, hybridization, and biased mating type ratios in Letharia
Ament-Velasquez, S. L.; Tuovinen, V.; Bergström, L.; Spribille, T.; Vanderpool, D.; Nascimbene, J.; Yamamoto, Y.; Thor, G.; Johannesson, H.
10.1101/2020.12.18.423428 — evolutionary biology — Posted on 2020-12-20
1308 Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence
Zampetidis, C.; Galanos, P.; Angelopoulou, A.; Zhu, Y.; Karamitros, T.; Lagopati, N.; Mirzazadeh, R.; Polyzos, A.; Garnerone, S.; Gusmao, E. G.; Sofiadis, K.; Pefani, D. E.; Demaria, M.; Crosetto, N.; Maya-Mendoza, A.; Evangelou, K.; Bartek, J.; Papantonis, A.; Gorgoulis, V. G.
10.1101/2020.12.20.423639 — cell biology — Posted on 2020-12-20
1309 Functional tagging of endogenous proteins and rapid selection of cell pools (Rapid generation of endogenously tagged piwi in ovarian somatic sheath cells.)
Marlin Andrews, C.; Konstantinidou, P.; Genzor, P.; Stoyko, D.; Elchert, A. R.; Benner, L.; Sobti, S.; Katz, E. Y.; Meng, Q.; Haase, A. D.
10.1101/2020.12.18.423517 — cell biology — Posted on 2020-12-20
1310 Cell-type specific analysis of physiological action of estrogen in mouse oviducts
McGlade, E. A.; Herrera, G. G.; Stephens, K. K.; Olsen, S. L.; Winuthayanon, S.; Guner, J.; Hewitt, S. C.; Korach, K. S.; DeMayo, F. J.; Lydon, J. P.; Monsivais, D.; Winuthayanon, W.
10.1101/2020.12.18.423483 — cell biology — Posted on 2020-12-20
1319 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
Pras, A.; Houben, B.; Aprile, F. A.; Seinstra, R.; Gallardo, R.; Janssen, L.; Hogewerf, W.; De Vleeschouwer, M.; Mata-Cabana, A.; Koopman, M.; Stroo, E.; De Vries, M.; Edwards, S. L.; Vendruscolo, M.; Falsone, F.; Rousseau, F.; Schymkowitz, J.; Nollen, E. A. A.
10.1101/2020.12.09.417709 — molecular biology — Posted on 2020-12-21
1322 Prochlorococcus extracellular vesicles: Molecular composition and adsorption to diverse microbes
Biller, S. J.; Lundeen, R. A.; Hmelo, L. R.; Becker, K. W.; Arellano, A. A.; Dooley, K.; Heal, K. R.; Carlson, L. T.; Van Mooy, B. A.; Ingalls, A. E.; Chisholm, S. W.
10.1101/2020.12.18.423521 — microbiology — Posted on 2020-12-20
1325 Identification of NPC1 as a novel SARS-CoV-2 intracellular target
Garcia-Dorival, I.; Cuesta-Geijo, M. A.; Barrado-Gil, L.; Galindo, I.; Urquiza, J.; Del Puerto, A.; Gil, C.; Campillo, N.; Martinez, A.; Alonso, C.
10.1101/2020.12.19.423584 — microbiology — Posted on 2020-12-20
1327 Biocontrol of Aspergillus niger in 3D-lung cell tissues by oxalotrophic bacteria
Palmieri, F.; Palmieri, I.; Noormamode, N.; Estoppey, A.; Ishak, M. O.; Kelliher, J. M.; Vallat, A.; Iyer, R.; Bindschedler, S.; Davenport, K.; Chain, P. S. G.; Harris, J. F.; Junier, P.
10.1101/2020.08.20.259929 — microbiology — Posted on 2020-12-20
1328 Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas
Ma, F.; Hughes, T. K.; Teles, R. M. B.; Andrade, P. R.; Silva, B. J. d. A.; Plazyo, O.; Tsoi, L. C.; Do, T.; Wadsworth, M. H.; Oulee, A.; Ochoa, M. T.; Sarno, E. N.; Iruela-Arispe, M. L.; Bryson, B.; Shalek, A. K.; Bloom, B. R.; Gudjonsson, J. E.; Pellegrini, M.; Modlin, R. L.
10.1101/2020.12.01.406819 — immunology — Posted on 2020-12-20
1331 Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions
Shiakolas, A. R.; Kramer, K. J.; Wrapp, D.; Richardson, S. I.; Schäfer, A.; Wall, S.; Wang, N.; Janowska, K.; Pilewski, K. A.; Venkat, R.; Parks, R.; Manamela, N. P.; Raju, N.; Friedman Fechter, E.; Holt, C. M.; Suryadevara, N.; Chen, R. E.; Martinez, D. R.; Nargi, R. S.; Sutton, R. E.; Ledgerwood, J. E.; Graham, B. S.; Diamond, M. S.; Haynes, B. F.; Acharya, P.; Carnahan, R. H.; Crowe, J. E.; Baric, R. S.; Morris, L.; McLellan, J. S.; Georgiev, I. S.
10.1101/2020.12.20.414748 — immunology — Posted on 2020-12-20
1332 SARS-CoV-2 escapes CD8 T cell surveillance via mutations in MHC-I restricted epitopes
Agerer, B.; Koblischke, M.; Gudipati, V.; Smyth, M.; Popa, A.; Genger, J.-W.; Endler, L.; Florian, D. M.; Muehlgrabner, V.; Lercher, A.; Gattinger, P.; Torralba-Gombau, R.; Penz, T.; Fae, I.; Wenda, S.; Traungott, M.; Walder, G.; Fischer, G.; Hoepler, W.; Pawelka, E.; Zoufaly, A.; Valenta, R.; Bock, C.; Huppa, J. B.; Aberle, J. H.; Bergthaler, A.
10.1101/2020.12.18.423507 — immunology — Posted on 2020-12-20
1340 Adaptive integration of self-motion and goals in posterior parietal cortex
Alexander, A. S.; Tung, J. C.; Chapman, G. W.; Shelley, L. E.; Hasselmo, M. E.; Nitz, D. A.
10.1101/2020.12.19.423589 — neuroscience — Posted on 2020-12-20
1341 Predicting speech from a cortical hierarchy of event-based timescales
Schmitt, L.-M.; Erb, J.; Tune, S.; Rysop, A.; Hartwigsen, G.; Obleser, J.
10.1101/2020.12.19.423616 — neuroscience — Posted on 2020-12-20
1343 A standardized behavioral event equally impacts the activity of cortical visual areas and layers
Ramadan, M.; Lee, E. K.; Caldejon, S.; Kato, I.; Roll, K.; Griffin, F.; Nguyen, T.; Larkin, J.; Rhoads, P.; Mace, K.; Kriedberg, A.; Howard, R.; Berbesque, N.; Lecoq, J.
10.1101/2020.12.15.422967 — neuroscience — Posted on 2020-12-20
1346 Orbitofrontal-hypothalamic projections are disrupted in hypermetabolic murine ALS model and human patients
Bayer, D.; Antonucci, S.; Mueller, H.-P.; Dupuis, L.; Boeckers, T. M.; Ludolph, A. C.; Kassubek, J.; Roselli, F.
10.1101/2020.11.28.402065 — neuroscience — Posted on 2020-12-20
1347 Primate neuronal connections are sparse as compared to mouse
Wildenberg, G. A.; Rosen, M. C.; Lundell, J.; Paukner, D.; Freedman, D. J.; Kasthuri, N.
10.1101/2020.09.24.311852 — neuroscience — Posted on 2020-12-20
1350 Blocking gephyrin phosphorylation or microglia BDNF signaling prevents synapse loss and reduces infarct volume after ischemia
Cramer, T.; Gill, R.; Thirouin, Z. S.; Vaas, M.; Sampath, S.; Martineau, F.; Noya, S. B.; Colameo, D.; Chang, P. K. Y.; Wu, P.; Barker, P.; Brown, S.; Paolicelli, R. C.; Klohs, J.; McKinney, A. R.; Tyagarajan, S. K.
10.1101/2020.04.22.055087 — neuroscience — Posted on 2020-12-20
1353 Leveraging selective hippocampal vulnerability among Alzheimer's disease subtypes reveals a novel tau binding partner SERPINA5
Crist, A. M.; Hinkle, K. M.; Wang, X.; Moloney, C. M.; Matchett, B. J.; Labuzan, S. A.; Frankenhauser, I.; Azu, N. O.; Liesinger, A. M.; Lesser, E. R.; Serie, D. J.; Quicksall, Z. S.; Patel, T. A.; Carnwath, T. P.; DeTure, M.; Tang, X.; Petersen, R. C.; Duara, R.; Graff-Radford, N. R.; Allen, M.; Carrasquillo, M. M.; Li, H.; Ross, O. A.; Ertekin-Taner, N.; Dickson, D. W.; Asmann, Y. W.; Carter, R. E.; Murray, M. E.
10.1101/2020.12.18.423469 — neuroscience — Posted on 2020-12-20
1354 Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension
Grundy, L.; Caldwell, A.; Garcia Caraballo, S.; Grundy, D.; Spencer, N.; Dong, X.; Castro, J.; Harrington, A. M.; Brierley, S.
10.1101/2020.12.18.423548 — neuroscience — Posted on 2020-12-20
1357 Cortical morphology predicts long-term placebo response in multiple sclerosis patients
Cherkasova, M.; Fu, J. F.; Jarrett, M.; Johnson, P.; Abel, S.; Tam, R.; Rauscher, A.; Sossi, V.; Kolind, S.; Li, D.; Sadovnick, A. D.; Machan, L.; Girard, J. M.; Emond, F.; Vosoughi, R.; Traboulsee, A.; Stoessl, A. J.
10.1101/825638 — neuroscience — Posted on 2020-12-21
1359 The first insight into the genetic structure of the population of modern Serbia
Drljaca, T.; Zukic, B.; Kovacevic, V.; Gemovic, B.; Klaassen-Ljubicic, K.; Perovic, V.; Lazarevic, M.; Pavlovic, S.; Veljkovic, N.
10.1101/2020.12.18.423408 — genomics — Posted on 2020-12-20
1360 Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker
Blake, G. E. T.; Zhao, X.; Yung, H. w.; Burton, G. J.; Ferguson-Smith, A. C.; Hamilton, R. S.; Watson, E. D.
10.1101/2020.05.21.109256 — genomics — Posted on 2020-12-20
1363 Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills.
Caramaschi, D.; Neumann, A.; Cardenas, A.; Tindula, G.; Alemany, S.; Zilich, L.; Pesce, G.; Lahti, J.; Havdahl, A.; Mulder, R.; Felix, J.; Tiemeier, H.; Sirignano, L.; Frank, J.; Witt, S.; Rietschel, M.; Deuschle, M.; Huen, K.; Eskenazi, B.; Send, T.; Ferrer, M.; Gilles, M.; de Agostini, M.; Baiz, N.; Rifas-Shiman, S.; Kvist, T.; Czamara, D.; Tuominen, S.; Relton, C.; Rai, D.; London, S.; Raikkonen, K.; Holland, N.; Annesi-Maesano, I.; Streit, F.; Hivert, M.-F.; Oken, E.; Sunyer, J.; Cecil, C.; Sharp, G.
10.1101/2020.12.18.423421 — developmental biology — Posted on 2020-12-20
1364 Cell patterning by secretion-induced plasma membrane flows
Gerganova, V.; Lamas, I.; Rutkowski, D. M.; Vjestica, A.; Gallo Castro, D.; Vincenzetti, V.; Vavylonis, D.; Martin, S. G.
10.1101/2020.12.18.423457 — cell biology — Posted on 2020-12-20
1365 IL-1R1 dependent signals improve clearance of cytosolic virulent mycobacteria in vivo
van der Niet, S.; van Zon, M.; de Punder, K.; Grootemaat, A.; Rutten, S.; Moorlag, S.; Houben, D.; van der Sar, A.; Bitter, W.; Brosch, R.; Hernandez, R.; Pena, M. T.; Peters, P. J.; Reits, E. E.; Mayer-Barber, K. D.; van der Wel, N.
10.1101/2020.09.27.315739 — cell biology — Posted on 2020-12-20
1366 Glycyrrhizin effectively neutralizes SARS-CoV-2 in vitro by inhibiting the viral main protease
van de Sand, L.; Bormann, M.; Alt, M.; Schipper, L.; Heilingloh, C. S.; Todt, D.; Dittmer, U.; Elsner, C.; Witzke, O.; Krawczyk, A.
10.1101/2020.12.18.423104 — molecular biology — Posted on 2020-12-20
1367 The Chemical Structure of Widespread Microbial Aryl Polyene Lipids
Grammbitter, G. L.; Shi, Y.-M.; Shi, Y.-N.; Vemulapalli, S. P.; Richter, C.; Schwalbe, H.; Alanjary, M.; Schueffler, A.; Witt, M.; Griesinger, C.; Bode, H. B.
10.1101/2020.12.19.423268 — microbiology — Posted on 2020-12-20
1368 Genome evolution in bacteria isolated from million-year-old subseafloor sediments
Orsi, W. D.; Magritsch, T.; Vargas, S.; Coskun, O. K.; Vuillemin, A.; Hohna, S.; Worheide, G.; D Hondt, S.; Shapiro, B. J.; Carini, P.
10.1101/2020.12.19.423498 — microbiology — Posted on 2020-12-20
1369 blaOXA-48-like genome architecture among carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in the Netherlands
Hendrickx, A. P. A.; Landman, F.; de Haan, A.; Borst, D.; Witteveen, S.; van Santen-Verheuvel, M. G.; Schouls, L. M.
10.1101/2020.12.18.423568 — microbiology — Posted on 2020-12-20
1370 Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
Whyte, C. E.; Singh, K.; Burton, O. T.; Aloulou, M.; Moudra, A.; Roca, C. P.; Naranjo, F. J.; Lombard-Vadnais, F.; Kouser, L.; Hochepied, T.; Halim, T. Y. F.; Schlenner, S.; Lesage, S.; Dooley, J.; Liston, A.
10.1101/2020.12.18.423431 — immunology — Posted on 2020-12-20
1371 Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity
Specht, H.; Emmott, E.; Petelski, A.; Huffman, R. G.; Perlman, D. H.; Serra, M.; Kharchenko, P.; Koller, A.; Slavov, N.
10.1101/665307 — immunology — Posted on 2020-12-20
1372 Application of the Anatomical Fiducials Framework to a Clinical Dataset of Patients with Parkinsons Disease
Abbass, M.; Gilmore, G.; Taha, A.; Chevalier, R.; Jach, M.; Peters, T. M.; Khan, A. R.; Lau, J. C.
10.1101/2020.12.17.423333 — neuroscience — Posted on 2020-12-20
1374 Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: evidence for an implication of oligodendrocyte progenitor cells
Tanti, A.; Belliveau, C.; Nagy, C.; Maitra, M.; Denux, F.; Perlman, K.; Chen, F.; Mpai, R.; Canonne, C.; Davoli, M. A.; Turecki, G.; Mechawar, N.
10.1101/2020.10.19.345355 — neuroscience — Posted on 2020-12-20
1376 Multisensory processes can compensate for attention deficits in schizophrenia
Moran, J. K.; Keil, J.; Masurovsky, A.; Gutwinski, S.; Montag, C.; Senkowski, D.
10.1101/2020.08.14.251405 — neuroscience — Posted on 2020-12-20
1377 Cannabidiol effects on cocaine-seeking behaviour and incubation of craving in mice.
Alegre-Zurano, L.; Lujan, M. A.; Cantacorps, L.; Martin-Sanchez, A.; Garcia-Baos, A.; Valverde, O.
10.1101/2020.12.18.423391 — neuroscience — Posted on 2020-12-20
1378 Recovery of neural dynamics criticality in personalized whole brain models of stroke
Rocha, R. P.; Kocillari, L.; Suweis, S.; De Grazia, M. D. F.; Thiebaut de Schotten, M.; Zorzi, M.; Corbetta, M.
10.1101/2020.12.17.423349 — neuroscience — Posted on 2020-12-20
1380 League of Brazilian Bioinformatics: a competition framework to promote scientific training
Carvalho, L. M.; Coimbra, N.; Camargo Neves, M. R.; Fonseca, N.; Costa, M.; Horacio, E.; Riyuzo, R.; Aburjaile, F.; Nagamatsu, S.
10.1101/2020.12.17.423357 — scientific communication and education — Posted on 2020-12-20
1382 Neuroanatomy of the grey seal brain: bringing pinnipeds into the neurobiological study of vocal learning
Hoeksema, N.; Verga, L.; Mengede, J.; van Roessel, C.; Villanueva, S.; Salazar-Casals, A.; Rubio-Garcia, A.; Curcic-Blake, B.; Vernes, S.; Ravignani, A.
10.1101/2020.12.19.423579 — animal behavior and cognition — Posted on 2020-12-19
1383 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.
10.1101/2020.11.27.399857 — genomics — Posted on 2020-12-20
1386 Naa12 rescues embryonic lethality in Naa10-Deficient Mice in the amino-terminal acetylation pathway
Kweon, H. Y.; Lee, M.; Dorfel, M.; Seo, S.; Gottlieb, L.; PaPazyan, T.; McTiernan, N.; Ree, R.; Garcia, A.; Flory, M.; Crain, J.; Sebold, A.; Lyons, S.; Ismail, A.; Marchi, E.; Sonn, S.-k.; Jeong, S.-J.; Jeon, S.; Ju, S.; Conway, S. J.; Kim, T.; Kim, H.-S.; Lee, C.; Roh, T.-Y.; Arnesen, T.; Marmorstein, R.; Lyon, G. J.; Oh, G.
10.1101/2020.12.19.422860 — developmental biology — Posted on 2020-12-20
1390 Sterilizing immunity against SARS-CoV-2 in hamsters conferred by a novel recombinant subunit vaccine
wu, y.; Huang, X.; Yuan, L.; Wang, S.; Zhang, Y.; Xiong, H.; Chen, R.; Ma, J.; Qi, R.; Nie, M.; Xu, J.; Zhang, Z.; Chen, L.; Wei, M.; Zhou, M.; Cai, M.; Shi, Y.; Zhang, L.; Yu, H.; Hong, J.; Wang, Z.; Hong, Y.; Yue, M.; Li, Z.; Chen, D.; Zheng, Q.; Li, S.; Chen, Y.; Cheng, T.; Zhang, J.; Zhang, T.; Zhu, H.; Zhao, Q.; Yuan, Q.; Guan, Y.; Xia, N.
10.1101/2020.12.18.423552 — microbiology — Posted on 2020-12-20
1393 The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I IFN and IFITM2
Winstone, H.; Lista Brotos, M. J.; Reid, A.; Pickering, S.; Doores, K. J.; Swanson, C. M.; Neil, S.
10.1101/2020.12.19.423592 — immunology — Posted on 2020-12-20
1394 Quantifying a Frequency Modulation Response Biomarker in Responsive Neurostimulation
Venkatesh, P.; Sneider, D.; Danish, M.; Sisterson, N. D.; Zaher, N.; Urban, A.; Grover, P.; Richardson, R. M.; Kokkinos, V.
10.1101/2020.12.17.423339 — neuroscience — Posted on 2020-12-20
1396 An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity
Kitamura, N.; Sacco, M. D.; Ma, C.; Hu, Y.; Townsend, J.; Meng, X.; Zhang, F.; Zhang, X.; Kukuljac, A.; Marty, M.; Schultz, D.; Cherry, S.; Xiang, Y.; Chen, Y.; Wang, J.
10.1101/2020.12.19.423537 — pharmacology and toxicology — Posted on 2020-12-20
1400 A comprehensive library of fluorescent constructs of SARS-CoV-2 proteins and their initial characterization in different cell types
Miserey-Lenkei, S.; Trajkovic, K.; D'Ambrosio, J. M.; Patel, A. J.; Copic, A.; Mathur, P.; Schauer, K.; Goud, b.; Albanese, V.; Gautier, R.; Subra, M.; Kovacs, D.; Barelli, H.; Antonny, B.
10.1101/2020.12.19.423586 — cell biology — Posted on 2020-12-19
1401 Longitudinal omics in Syrian hamsters integrated with human data unravel complexity of moderate immune responses to SARS-CoV-2
Nouailles, G.; Wyler, E.; Pennitz, P.; Postmus, D.; Vladimirova, D.; Kazmierski, J.; Pott, F.; Dietert, K.; Mülleder, M.; Farztdinov, V.; Obermayer, B.; Wienhold, S.-M.; Andreotti, S.; Höfler, T.; Sawitzki, B.; Drosten, C.; Sander, L. E.; Suttorp, N.; Ralser, M.; Beule, D.; Gruber, A. D.; Goffinet, C.; Landthaler, M.; Trimpert, J.; Witzenrath, M.
10.1101/2020.12.18.423524 — immunology — Posted on 2020-12-19
1402 Fast and scalable lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro
Wang, G.; Gaikwad, H.; McCarthy, M. K.; Gonzalez-Juarrero, M.; Li, Y.; Armstrong, M.; Reisdorf, N.; Morrison, T. E.; Simberg, D.
10.1101/2020.12.18.423509 — pharmacology and toxicology — Posted on 2020-12-19
1403 Indisulam targets RNA splicing and metabolism to serve as a novel therapeutic strategy for high-risk neuroblastoma
Nijhuis, A.; Sikka, A.; Yogev, O.; Herendi, L.; Eckold, C.; Valbuena, G.; Liu, Y.; Kouloura, E.; Poon, E.; Martins da Costa, B.; Benito, A.; Kramer, H.; Montoya, A.; Carling, D.; Want, E. J.; Jamin, Y.; Chesler, L.; Keun, H. C.
10.1101/2020.12.18.423403 — cancer biology — Posted on 2020-12-19
1405 Multi-omics analysis of chromatin accessibility and interactions with transcriptome by HiCAR
Wei, X.; Xiang, Y.; Shan, R.; Peters, D. T.; Sun, T.; Lin, X.; Li, W.; Diao, Y.
10.1101/2020.11.02.366062 — genomics — Posted on 2020-12-19
1406 A highly conserved binding pocket on PP2A-B56 is required for shugoshin binding and cohesion protection
Ueki, Y.; Hadders, M.; Weisser, M. B.; Nasa, I.; Gupta, T.; Hertz, E. T.; Kruse, T.; Montoya, G.; Jeyaprakash, A. A.; Kettenbach, A.; Lens, S. M. A.; Nilsson, J.
10.1101/2020.12.18.423432 — cell biology — Posted on 2020-12-19
1408 Tau-first subtype of Alzheimer's disease consistently identified across in vivo and post mortem studies
Aksman, L. M.; Oxtoby, N. P.; Scelsi, M. A.; Wijeratne, P. A.; Young, A. L.; Lopes Alves, I.; Barkhof, F.; Alexander, D. C.; Altmann, A.
10.1101/2020.12.18.418004 — neuroscience — Posted on 2020-12-19
1411 The distribution of onion virulence gene clusters among Pantoea spp.
Stice, S.; Shin, G.-Y.; De Armas, S.; Koirala, S.; Galvan, G. A.; Siri, M. I.; Severns, P.; Coutinho, T.; Dutta, B.; Kvitko, B. H.
10.1101/2020.12.18.423501 — plant biology — Posted on 2020-12-19
1414 Molecular fluctuations as a ruler of force-induced protein conformations
Stannard, A.; Mora, M.; Beedle, A. E. M.; Castro-Lopez, M.; Board, S.; Garcia-Manyes, S.
10.1101/2020.12.18.423481 — biophysics — Posted on 2020-12-19
1421 Coupling of Cdc20 inhibition and activation by BubR1
Hein, J.; Garvanska, D. H.; Nasa, I.; Kettenbach, A.; Nilsson, J.
10.1101/2020.12.18.423461 — cell biology — Posted on 2020-12-19
1422 Highly efficient genome editing in hematopoietic stem and progenitor cells
Verhagen, H. J.; Kuijk, C.; Kokke, A. M.; Rutgers, L.; van der Meulen, S.; van Mierlo, G.; VOERMANS, C.; Van den akker, E.
10.1101/2020.12.18.423329 — molecular biology — Posted on 2020-12-19
1424 Improved microbial community characterization of 16S rRNA via metagenome hybridization capture enrichment
Beaudry, M. S.; Wang, J.; Kieran, T.; Thomas, J.; Bayona-Vasquez, N. J.; Gao, B.; Devault, A.; Brunelle, B.; Lu, K.; Wang, J.-S.; Rhodes, O. E.; Glenn, T. C.
10.1101/2020.12.18.423101 — microbiology — Posted on 2020-12-19
1427 Neural stem cells restore motor and cognitive function in a macaque model of Parkinson's disease
Wianny, F.; Dzahini, K.; Fifel, K.; Wilson, C. R. E.; Bernat, A.; Dolmazon, V.; Misery, P.; Lamy, C.; Cooper, H. M.; Procyk, E.; Kennedy, H.; Savatier, P.; Dehay, C.; Vezoli, J.
10.1101/2020.12.17.423293 — neuroscience — Posted on 2020-12-19
1429 Autonomous sensing the insulin peptide by an olfactory G protein coupled receptor modulates glucose metabolism
Cheng, J.; Yang, Z.; Ge, X.-Y.; Gao, M.-X.; Meng, R.; Lin, J.-Y.; Tian, Z.-M.; Xu, Y.-F.; Yang, F.; Sun, J.-P.; Yu, X.
10.1101/2020.12.18.423228 — physiology — Posted on 2020-12-19
1430 Biomimetic, smart and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging
Rota Sperti, F.; Charbonnier, T.; Lejault, P.; Zell, J.; Bernhard, C.; Valverde, I. E.; Monchaud, D.
10.1101/2020.12.18.422878 — biophysics — Posted on 2020-12-18
1434 TIPS: Trajectory Inference of Pathway Significance through Pseudotime Comparison for Functional Assessment of single-cell RNAseq Data
Zheng, Z.; Xin, Q.; Wu, H.; Chang, L.; Tang, X.; Zou, L.; Li, J.; Wu, Y.; Zhou, J.; shan, j.; Wan, Y.; Ni, Q.
10.1101/2020.12.17.423360 — bioinformatics — Posted on 2020-12-19
1435 Identifying genes with cell-type-specific alternative polyadenylation in multi-cluster single-cell transcriptomics data
Bai, Y.; Qin, Y.; Fan, Z.; Morrison, R. M.; Nam, K.; Zarour, H. M.; Koldamova, R.; Padiath, Q. S.; Kim, S.; Park, H. J.
10.1101/2020.07.30.229096 — bioinformatics — Posted on 2020-12-19
1437 Massively parallel quantification of phenotypic heterogeneity in single cell drug responses
Yellen, B. B.; Zawistowski, J. S.; Czech, E. A.; Sanford, C. I.; SoRelle, E. D.; Luftig, M. A.; Forbes, Z. G.; Wood, K. C.; Hammerbacher, J.
10.1101/2020.12.18.423559 — bioengineering — Posted on 2020-12-18
1438 TFMLAB: a MATLAB toolbox for 4D traction force microscopy
Barrasa Fano, J.; Shapeti, A.; Jorge-Penas, A.; Barzegari, M.; Sanz Herrera, J. A.; Van Oosterwyck, H.
10.1101/2020.12.18.423056 — bioengineering — Posted on 2020-12-19
1440 Do honey bee species differ in the odometer used for the waggle dance?
George, E. A.; Thulasi, N.; Kohl, P. L.; Suresh, S.; Rutschmann, B.; Brockmann, A.
10.1101/2020.12.17.423277 — animal behavior and cognition — Posted on 2020-12-18
1441 Epigenetic heterogeneity after de novo assembly of native full-length Hepatitis B Virus genomes
Goldsmith, C. D.; Cohen, D.; Dubois, A.; Martinez, M.-G.; Petitjean, K.; Corlu, A.; Hernandez-Vargas, H.; Chemin, I.
10.1101/2020.05.29.122259 — genomics — Posted on 2020-12-18
1442 Single-cell analysis of chromatin silencing programs in developmental and tumor progression
Wu, S. J.; Furlan, S. N.; Mihalas, A. B.; Kaya-Okur, H.; Feroze, A. H.; Emerson, S. N.; Zheng, Y.; Carson, K.; Cimino, P. J.; Keene, C. D.; Sarthy, J. F.; Gottardo, R.; Ahmad, K.; Henikoff, S.; Patel, A. P.
10.1101/2020.09.04.282418 — genomics — Posted on 2020-12-19
1443 A systems genomics approach uncovers molecular associates of RSV severity
McCall, M. N.; Chu, C.-Y.; Wang, L.; Benoodt, L.; Thakar, J.; Corbett, A.; Holden-Wiltse, J.; Slaunwhite, C.; Grier, A.; Gill, S.; Falsey, A. R.; Topham, D. J.; Caserta, M.; Walsh, E.; Qiu, X.; Mariani, T. J.
10.1101/2020.12.18.423266 — genomics — Posted on 2020-12-19
1444 Genetics of white color and iridophoroma in "Lemon Frost" leopard geckos
Guo, L.; Bloom, J. S.; Sykes, S.; Huang, E.; Kashif, Z.; Pham, E.; Ho, K.; Alcaraz, A.; Xiao, X. G.; Duarte-Vogel, S.; Kruglyak, L.
10.1101/2020.12.18.423549 — genetics — Posted on 2020-12-19
1446 Using Community Science to Reveal the Global Chemogeography of River Metabolomes
Garayburu-Caruso, V. A.; Danczak, R. E.; Stegen, J.; Renteria, L.; MacCall, M.; Goldman, A. E.; Chu, R. K.; Toyoda, J.; Resch, C. T.; Torgeson, J. M.; Wells, J.; Fansler, S.; Kumar, S.; Graham, E. B.
10.1101/2020.11.02.362905 — ecology — Posted on 2020-12-18
1450 An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution
Howard, A. G. A.; Baker, P. A.; Ibarra-Garcia-Padilla, R.; Moore, J. A.; Rivas, L. J.; Tallman, J. J.; Singleton, E. W.; Westheimer, J. L.; Corteguera, J. A.; Uribe, R. A.
10.1101/2020.06.14.150938 — developmental biology — Posted on 2020-12-18
1452 FBW7 couples structural integrity with functional output of primary cilia
Petsouki, E.; Gerakopoulos, V.; Szeto, N.; Chang, W.; Humphrey, M. B.; Tsiokas, L.
10.1101/2020.12.18.423369 — cell biology — Posted on 2020-12-18
1454 Automated hiPSC culture and sample preparation for 3D live cell microscopy
Coston, M. E.; Gregor, B. W.; Arakaki, J.; Borensztejn, A.; Do, T. P.; Fuqua, M. A.; Haupt, A.; Hendershott, M. C.; Leung, W.; Mueller, I. A.; Nelson, A. M.; Rafelski, S. M.; Swain-Bowden, M. J.; Tang, W. J.; Thirstrup, D. J.; Wiegraebe, W.; Yan, C.; Gunawardane, R. N.; Gaudreault, N.
10.1101/2020.12.18.423371 — cell biology — Posted on 2020-12-19
1456 Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator
Sanborn, A. L.; Yeh, B. T.; Feigerle, J. T.; Hao, C. V.; Townshend, R. J. L.; Aiden, E. L.; Dror, R. O.; Kornberg, R. D.
10.1101/2020.12.18.423551 — molecular biology — Posted on 2020-12-18
1458 Neural heterogeneity promotes robust learning
Perez-Nieves, N.; Leung, V. C. H.; Dragotti, P. L.; Goodman, D. F. M.
10.1101/2020.12.18.423468 — neuroscience — Posted on 2020-12-18
1460 Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super-relaxed state: multiscale measurements and computational modeling
Vander Roest, A. S.; Liu, C.; Morck, M. M.; Kooiker, K. B.; Jung, G.; Song, D.; Dawood, A.; Jhingran, A.; Pardon, G.; Ranjbarvaziri, S.; Fajardo, G.; Zhao, M.; Campbell, K. S.; Pruitt, B.; Spudich, J. A.; Ruppel, K. M.; Bernstein, D.
10.1101/2020.11.10.375493 — biophysics — Posted on 2020-12-18
1466 Evidence for distinct genetic and environmental influences on fear acquisition and extinction
Purves, K. L.; Krebs, G.; McGregor, T.; Constantinou, E.; Lester, K. J.; Barry, T. J.; Craske, M. G.; Young, K. S.; Breen, G.; Eley, T. C.
10.1101/2020.12.18.423504 — genetics — Posted on 2020-12-18
1468 Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks
Zhou, Q.; Perovic, T.; Fechner, I.; Edgar, L. T.; Hoskins, P. R.; Gerhardt, H.; Krüger, T.; Bernabeu, M. O.
10.1101/2020.05.21.106914 — developmental biology — Posted on 2020-12-18
1469 Threshold accumulation of a constitutive protein explains E. coli cell division behavior in nutrient upshifts.
Panlilio, M.; Grilli, J.; Tallarico, G.; Iuliani, I.; Sclavi, B.; Cicuta, P.; Cosentino Lagomarsino, M.
10.1101/2020.08.03.233908 — cell biology — Posted on 2020-12-18
1470 Interspecies metabolite transfer and aggregate formation in a co-culture of Dehalococcoides and Sulfurospirillum dehalogenating tetrachloroethene to ethene
Kruse, S.; Tuerkowsky, D.; Birkigt, J.; Matturro, B.; Franke, S.; Jehmlich, N.; von Bergen, M.; Westermann, M.; Rossetti, S.; Nijenhuis, I.; Adrian, L.; Diekert, G.; Goris, T.
10.1101/526210 — microbiology — Posted on 2020-12-18
1471 Dominant Remodeling of Cattle Rumen Microbiome by Schedonorus arundinaceus (Tall Fescue) KY-31 Carrying a Fungal Endophyte
Khairunisa, B. H.; Susanti, D.; Loganathan, U.; Teutsch, C. D.; Campbell, B. T.; Fiske, D.; Wilkinson, C. A.; Aylward, F. O.; Mukhopadhyay, B.
10.1101/2020.12.18.423411 — microbiology — Posted on 2020-12-18
1472 Metabolism modulates network synchrony in the aging brain
Weistuch, C.; Mujica-Parodi, L. R.; Amgalan, A.; Dill, K. A.
10.1101/2020.04.17.047233 — neuroscience — Posted on 2020-12-18
1474 Functional idiosyncrasy has a shared topography with group-level connectivity alterations in autism
Benkarim, O.; Paquola, C.; Park, B.-y.; Hong, S.-J.; Royer, J.; Vos de Wael, R.; Lariviere, S.; Valk, S.; Bzdok, D.; Mottron, L.; Bernhardt, B.
10.1101/2020.12.18.423291 — neuroscience — Posted on 2020-12-18
1479 Tumor invasion as non-equilibrium phase separation
Kang, W.; Ferruzzi, J.; Spatarelu, C.-P.; Han, Y. L.; Sharma, Y.; Koehler, S.; Butler, J. P.; Roblyer, D.; Zaman, M. H.; Guo, M.; Chen, Z.; Pegoraro, A. F.; Fredberg, J. J.
10.1101/2020.04.28.066845 — biophysics — Posted on 2020-12-18
1481 Neural network fast-classifies biological images using features selected after their random-forests-importance to power smart microscopy.
Balluet, M.; Sizaire, F.; El Habouz, Y.; Walter, T.; Pont, J.; Giroux, B.; Bouchareb, O.; Tramier, M.; Pecreaux, J.
10.1101/2020.11.10.376988 — bioinformatics — Posted on 2020-12-18
1482 Combinatorial Polyacrylamide Hydrogels for Preventing Biofouling on Implantable Biosensors
Chan, D.; Chien, J.-C.; Axpe, E.; Blankemeier, L.; Baker, S. W.; Swaminathan, S.; Piunova, V. A.; Zubarev, D. Y.; Maikawa, C. L.; Soh, H. T.; Appel, E. A.
10.1101/2020.05.25.115675 — bioengineering — Posted on 2020-12-18
1483 Wnt/β-Catenin Signaling Controls Spatio-Temporal Elasticity Patterns in Extracellular Matrix during Hydra Morphogenesis
Veschgini, M.; Petersen, H. O.; Abuillan, W.; Rossetti, F. F.; Özbek, S.; Burghammer, M.; Holstein, T. W.; Tanaka, M.
10.1101/214718 — developmental biology — Posted on 2020-12-18
1487 Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation
Miletic, S.; Fahrenkamp, D.; Goessweiner-Mohr, N.; Wald, J.; Pantel, M.; Vesper, O.; Kotov, V.; Marlovits, T. C.
10.1101/2020.12.17.423328 — molecular biology — Posted on 2020-12-18
1494 Capturing Human Trophoblast Development with Naive Pluripotent Stem Cells In Vitro
Io, S.; Kabata, M.; Iemura, Y.; Semi, K.; Morone, N.; Okamoto, I.; Nakamura, T.; Kojima, Y.; Iwatani, C.; Tsuchiya, H.; Kaswandy, B.; Kondoh, E.; Saitou, M.; Yamamoto, T.; Mandai, M.; Takashima, Y.
10.1101/2020.12.17.416800 — developmental biology — Posted on 2020-12-18
1495 Atg4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system
Nguyen, T. N.; Padman, B. S.; Zellner, S.; Uoselis, L.; Skulsuppaisarn, M.; Behrends, C.; Lazarou, M.
10.1101/2020.12.17.422596 — cell biology — Posted on 2020-12-18
1496 Divergent molecular signatures of regeneration and fibrosis during wound repair
Mascharak, S.; desJardins-Park, H. E.; Januszyk, M.; Chen, K.; Davitt, M. F.; Demeter, J.; Henn, D.; Griffin, M.; Bonham, C. A.; Foster, D. S.; Mooney, N. A.; Cheng, R.; Jackson, P. K.; Wan, D. C.; Gurtner, G. C.; Longaker, M. T.
10.1101/2020.12.17.423181 — cell biology — Posted on 2020-12-18
1497 Modeling population size independent tissue epigenomes by ChIL-seq with single-thin sections
Maehara, K.; Tomimatsu, K.; Harada, A.; Tanaka, K.; Sato, S.; Okada, S.; Handa, T.; Kurumizaka, H.; Kimura, H.; Ohkawa, Y.
10.1101/2020.12.18.423434 — molecular biology — Posted on 2020-12-18
1499 Human Adenovirus Type 4 Comprises Two Mayor Phylogroups With Distinct Phenotypes Relevant To Pathogenesis
Bair, C. R.; Zhang, W.; Gonzalez, G.; Kamali, A.; Stylos, D.; Blanco, J. C. G.; Kajon, A. E.
10.1101/2020.12.18.365858 — microbiology — Posted on 2020-12-18
1502 Broad transcriptomic dysregulation across the cerebral cortex in ASD
Haney, J. R.; Wamsley, B.; Chen, G. T.; Parhami, S.; Emani, P. S.; Chang, N.; Hoftman, G. D.; de Alba, D.; Kale, G.; Ramaswami, G.; Hartl, C. L.; Jin, T.; Wang, D.; Ou, J.; Wu, Y. E.; Parikshak, N. N.; Swarup, V.; Belgard, T. G.; Gerstein, M.; Pasaniuc, B.; Gandal, M. J.; Geschwind, D. H.
10.1101/2020.12.17.423129 — neuroscience — Posted on 2020-12-18
1503 C57BL6 mouse substrains demonstrate differences in susceptibility to the demyelinating effects of Cuprizone toxin
O'Loughlin, E. K.; Jacob, B.; Zeballos, G. Z.; Manfre, P.; McCullough, A.; Gatto, N.; Tsuchiya, T.; Karkkainen, A.-M.; Lehtimaki, K.; Kuosmanen, J.; Rosahl, T. W.; Varty, G. B.; Kennedy, M. E.; Mirescu, C.; Bardehle, S.
10.1101/2020.12.17.423334 — neuroscience — Posted on 2020-12-18
1504 Quantitative cross-species translators of cardiac myocyte electrophysiology: model training, experimental validation, and applications
Morotti, S.; Liu, C.; Hegyi, B.; Ni, H.; Fogli Iseppe, A.; Wang, L.; Ripplinger, C. M.; Bers, D. M.; Edwards, A. G.; Grandi, E.
10.1101/2020.12.17.423297 — systems biology — Posted on 2020-12-18
1507 Development and validation of a combined species SNP array for the European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata)
Penaloza, C.; Manousaki, T.; Franch, R.; Tsakogiannis, A.; Sonesson, A.; Aslam, L.; Allal, F.; Bargelloni, L.; Houston, R. D.; Tsigenopoulos, C. S.
10.1101/2020.12.17.423305 — genomics — Posted on 2020-12-18
1508 Analysis of Genetically Determined Gene Expression Suggests Role of Inflammatory Processes in Exfoliation Syndrome
Hirbo, J. B.; Pasutto, F.; Gamazon, E. R.; Evans, P.; Pawar, P.; Berner, D.; Sealock, J.; Tao, R.; Straub, P. S.; Konkashbaev, A. I.; Breyer, M. A.; Schlötzer-Schrehardt, U.; Reis, A.; Brantley, M. A.; Khor, C. C.; Joos, K. M.; Cox, N. J.
10.1101/2020.12.17.423318 — genetics — Posted on 2020-12-18
1510 Maternal vitamin D deficiency impairs heart formation in mouse offspring through a change in 3D-chromatin structure
Seipelt, E.; Bensadoun, P.; Sati, S.; Couturier, C.; Astier, J.; Mounien, L.; Landrier, J.-F.; Puceat, M.
10.1101/2020.12.17.423263 — developmental biology — Posted on 2020-12-18
1512 Redistribution of FLAgellar Member 8 during the trypanosome life cycle: consequences for cell fate prediction.
CALVO ALVAREZ, E.; BONNEFOY, S.; SALLES, A.; BENSON, F. E.; McKEAN, P. G.; BASTIN, P.; ROTUREAU, B.
10.1101/2020.12.17.423316 — microbiology — Posted on 2020-12-18
1513 Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
Wilk, A. J.; Lee, M. J.; Wei, B.; Parks, B.; Pi, R.; Martinez-Colon, G. J.; Ranganath, T.; Zhao, N. Q.; Taylor, S.; Becker, W.; Stanford COVID-19 Biobank, ; Jimenez-Morales, D.; Blomkalns, A. L.; O'Hara, R.; Ashley, E. A.; Nadeau, K. C.; Yang, S.; Holmes, S.; Rabinovitch, M.; Rogers, A. J.; Greenleaf, W. J.; Blish, C. A.
10.1101/2020.12.18.423363 — immunology — Posted on 2020-12-18
1515 SNPnexus COVID: Facilitating the analysis of COVID-19 host genetics
Oscanoa, J.; Sivapalan, L.; Abdollahyan, M.; Gadaleta, E.; Chelala, C.
10.1101/2020.12.18.423439 — genomics — Posted on 2020-12-18
1517 Temporal kinetics of RNAemia and associated systemic cytokines in hospitalized COVID-19 patients
van Riel, D.; Embregts, C.; Sips, G. J.; van den Akker, J.; Endeman, H.; van Nood, E.; van Kampen, J. J.; Molenkamp, R.; Koopmans, M.; van de vijver, d.; GeurtsvanKessel, C.
10.1101/2020.12.17.423376 — microbiology — Posted on 2020-12-18
1518 An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies
Liu, Y.; Soh, W. T.; Tada, A.; Arakawa, A.; Matsuoka, S.; Nakayama, E. E.; Li, S.; Ono, C.; Torii, S.; Kishida, K.; Jin, H.; Nakai, W.; Arase, N.; Nakagawa, A.; Shindo, Y.; Kohyama, M.; Nakagami, H.; Tomii, K.; Ohmura, K.; Ohshima, S.; Okada, M.; Matsuura, Y.; Standley, D. M.; Shioda, T.; Arase, H.
10.1101/2020.12.18.423358 — microbiology — Posted on 2020-12-18
1521 A recombinant fragment of Human surfactant protein D binds Spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samples
Madan, T.; Biswas, B.; Varghese, P.; Subedi, R.; Pandit, H.; Idicula-Thomas, S.; Kundu, I.; Rooge, S. B.; Aggarwal, R.; Tripathi, D.; Kaur, S.; Gupta, E.; Gupta, S.; Kishore, U.
10.1101/2020.12.18.423415 — immunology — Posted on 2020-12-18
1526 Towards a unified theory of plant photosynthesis and hydraulics
Joshi, J.; Stocker, B. D.; Hofhansl, F.; Zhou, S.; Dieckmann, U.; Prentice, I. C.
10.1101/2020.12.17.423132 — plant biology — Posted on 2020-12-18
1527 Vimentin provides target search efficiency and mechanical resilience for dendritic cell migration
Da Cunha Stankevicins, L.; Shaebani, M. R.; Vesperini, D.; Urbanska, M.; Flormann, D. A. D.; Terriac, E.; Gad, A. K. B.; Cheng, F.; Eriksson, J.; Lautenschlaeger, F.
10.1101/2020.12.18.423401 — biophysics — Posted on 2020-12-18
1530 Probing T-cell response by sequence-based probabilistic modeling
Bravi, B.; Balachandran, V. P.; Greenbaum, B. D.; Walczak, A. M.; Mora, T.; Monasson, R.; Cocco, S.
10.1101/2020.12.17.423283 — bioinformatics — Posted on 2020-12-18
1531 Pollen sterols are associated with phylogenetics and environment but not with pollinators
Zu, P.; Koch, H.; Schwery, O.; Pironon, S.; Phillips, C.; Ondo, I.; Farrell, I.; Nes, W. D.; Moore, E.; Wright, G.; Farman, D. I.; Stevenson, P. C.
10.1101/2020.12.18.423259 — biochemistry — Posted on 2020-12-18
1535 Mutually inclusive mechanisms of drought-induced tree mortality
Hajek, P.; Link, R. M.; Nock, C.; Bauhus, J.; Gebauer, T.; Gessler, A.; Kovach, K.; Messier, C.; Paquette, A.; Saurer, M.; Scherer-Lorenzen, M.; Rose, L.; Schuldt, B.
10.1101/2020.12.17.423038 — ecology — Posted on 2020-12-18
1540 Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1
Lewis, R. S.; van Dorp, S.; Qiu, R.; Choi, U. B.; Wu, M. M.; Yen, M.; Kirmiz, M.; Brunger, A. T.
10.1101/2020.12.17.423361 — biophysics — Posted on 2020-12-18
1541 Biotic and abiotic factors shaping the genome of cockle (Cerastoderma edule) in the Northeast Atlantic: a baseline for sustainable management of its wild resources
Vera, M.; Maroso, F.; Wilmes, S. B.; Hermida, M.; Blanco, A.; Fernandez, C.; Groves, E.; Malham, S. K.; Bouza, C.; Martinez, P.
10.1101/2020.12.17.423063 — genomics — Posted on 2020-12-18
1548 Identifying selective drug combinations using Comparative Network Reconstruction
Bosdriesz, E.; Fernandes Neto, J. M.; Sieber, A.; Bernards, R. R.; Bluthgen, N.; Wessels, L.
10.1101/2020.12.17.423240 — systems biology — Posted on 2020-12-18
1553 Isothermal Amplification of Nucleic Acids with Ladder-shape Melting Curve
Wang, D.; Wang, Y.; Zhang, M.; Zhang, Y.; Sun, J.; Song, C.; Xiao, F.; Ping, Y.; Chen, P.; Hu, Y.; Wang, C.; Liu, Y.
10.1101/2020.12.17.423190 — biochemistry — Posted on 2020-12-18
1556 Sex-specific body mass ageing trajectories in adult Asian elephants
Lalande, L. D.; Lummaa, V.; Aung, H. H.; Htut, W.; Nyein, U. K.; Berger, V.; Briga, M.
10.1101/2020.12.17.423208 — evolutionary biology — Posted on 2020-12-18
1557 Rate-of-change analysis in palaeoecology revisited: a new approach
Mottl, O.; Grytes, J.-A.; Seddon, A. W. R.; Steinbauer, M. J.; Bhatta, K. P.; Felde, V. A.; Flantua, S. G. A.; Birks, H. J. B.
10.1101/2020.12.16.422943 — ecology — Posted on 2020-12-18
1561 MAPPER: A new image analysis pipeline unmasks differential regulation of Drosophila wing features
Kumar, N.; Huizar, F.; Robinett, T.; Farfan-Pira, K. J.; Soundarrajan, D. J.; Unger, M.; Brodskiy, P.; Nahmad, M.; Zartman, J. J.
10.1101/2020.12.16.422888 — developmental biology — Posted on 2020-12-18
1565 Activity flow underlying abnormalities in brain activations and cognition in schizophrenia
Hearne, L. J.; Mill, R. D.; Keane, B. P.; Repovs, G.; Anticevic, A.; Cole, M. W.
10.1101/2020.12.16.423109 — neuroscience — Posted on 2020-12-18
1568 The Wood Image Analysis and Dataset (WIAD): open-access visual analysis tools to advance the ecological data revolution
Rademacher, T.; Seyednasrollah, B.; Basler, D.; Cheng, J.; Mandra, T.; Miller, E.; Lin, Z.; Orwig, D. A.; Pederson, N.; Pfister, H.; Richardson, A. D.; Wei, D.; Yao, L.
10.1101/2020.12.16.423133 — plant biology — Posted on 2020-12-18
1570 Development of intra-oral automated landmark recognition (ALR) for dental and occlusal outcome measurements
Woodsend, B.; Koufoudaki, E.; Lin, P.; McIntyre, G.; El-Angbawi, A.; Aziz, A.; Shaw, W.; Semb, G.; Reesu, G. V.; Mossey, P. A.
10.1101/2020.12.16.423094 — bioinformatics — Posted on 2020-12-18
1571 Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice
Huang, S.; Bluetke, A.; Feuchtinger, A.; Klemm, U.; Tom, R. Z.; Hofmann, S.; Stiel, A. C.; Ntziachristos, V.
10.1101/2020.12.17.419531 — bioengineering — Posted on 2020-12-18
1572 Genomic and phylogenetic analyses of SARS-CoV-2 strains isolated in the city of Gwangju, South Korea
Min Ji, K.; Ji-eun, L.; Jae Keun, C.; Tae sun, K.; Jungwook, P.; Mi hyeon, L.; Da jeong, H.; Jin, J.; Ji-eun, Y.; Hye young, K.; Jin jong, S.; Kwang gon, K.
10.1101/2020.12.16.423178 — microbiology — Posted on 2020-12-18
1574 Catalytic Promiscuity of Rice 2-Oxoglutarate/Fe(II)-Dependent Dioxygenases Supports Xenobiotic Metabolism
Tozawa, Y.; Takamura, N.; Yamazaki, A.; Sakuma, N.; Hirose, S.; Takani, Y.; Sakai, M.; Oshima, M.; Kuroki, M.
10.1101/2020.12.17.423306 — plant biology — Posted on 2020-12-18
1575 Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Mayekar, M. K.; Caswell, D. R.; Vokes, N. I.; Law, E. K.; Wu, W.; Hill, W.; Gronroos, E.; Rowan, A.; Al Bakir, M.; McCoach, C. E.; Blakely, C. M.; Temiz, N. A.; Nagano, A.; Kerr, D. L.; Rotow, J. K.; Haderk, F.; Dietzen, M.; Ruiz, C. M.; Almeida, B.; Cech, L.; Gini, B.; Przewrocka, J.; Moore, C.; Murillo, M.; Bakker, B.; Rule, B.; Durfee, C.; Nanjo, S.; Tan, L.; Larson, L. K.; Argyris, P. P.; Brown, W. L.; Yu, J.; Gomez, C.; Gui, P.; Vogel, R. I.; Yu, E. A.; Thomas, N. J.; Venkatesan, S.; Hobor, S.; Chew, S. K.; Kanu, N.; McGranahan, N.; Van Allen, E. M.; Downward, J.; Harris, R. S.; Bivona, T
10.1101/2020.12.18.423280 — cancer biology — Posted on 2020-12-18
1576 WNT11 is a novel ligand for ROR2 in human breast cancer
Menck, K.; Heinrichs, S.; Wlochowitz, D.; Sitte, M.; Noeding, H.; Janshoff, A.; Treiber, H.; Ruhwedel, T.; Schatlo, B.; von der Brelie, C.; Wiemann, S.; Pukrop, T.; Beissbarth, T.; Binder, C.; Bleckmann, A.
10.1101/2020.12.18.423402 — cancer biology — Posted on 2020-12-18
1578 Megadepth: efficient coverage quantification for BigWigs and BAMs
Wilks, C.; Ahmed, O.; Baker, D. N.; Zhang, D.; Collado-Torres, L.; Langmead, B.
10.1101/2020.12.17.423317 — bioinformatics — Posted on 2020-12-18
1579 Glycan remodeled erythrocytes facilitate antigenic characterizationof recent A/H3N2 influenza viruses
Broszeit, F.; van Beek, R. J.; Unione, L.; Bestebroer, T. M.; Chapla, D.; Yang, J.-Y.; Moremen, K. W.; Herfst, S.; Foucher, R. A. M.; de Vries, R. P.; Boons, G.-J.
10.1101/2020.12.18.423398 — biochemistry — Posted on 2020-12-18
1580 Genome-wide DNA mutations in Arabidopsis plants after multigenerational exposure to high temperature
Lu, Z.; Cui, J.; Wang, L.; Teng, N.; Zhang, S.; Lam, H.-M.; Zhu, Y.; Xiao, S.; Ke, W.; Lin, J.; Xu, C.; Jin, B.
10.1101/2020.12.17.423344 — genetics — Posted on 2020-12-18
1581 Mangroves are an overlooked hotspot of insect diversity despite low plant diversity
Yeo, D.; Srivathsan, A.; Puniamoorthy, J.; Foo, M.; Grootaert, P.; Chan, L.; Guenard, B.; Damken, C.; Wahab, R. A.; Ang, Y.; Meier, R.
10.1101/2020.12.17.423191 — ecology — Posted on 2020-12-18
1582 The jasmine (Jasminum sambac) genome and flower fragrances
Chen, G.; Mostafa, S.; Lu, Z.; Du, R.; Cui, J.; Wang, Y.; Liao, Q.; Lu, J.; Mao, X.; Chang, B.; Wang, L.; Jia, Z.; Yang, X.; Zhu, Y.; Yan, J.; Jin, B.
10.1101/2020.12.17.420646 — plant biology — Posted on 2020-12-18
1584 A phenotypic screen identifies a compound series that induces differentiation of acute myeloid leukemia cells in vitro and shows anti-tumour effects in vivo
Jose-Cullere, L.; Madden, K. S.; Cogswell, T. J.; Jackson, T. R.; Carter, T. S.; Zhang, D.; Trevitt, G.; Davies, S. G.; Vyas, P.; Wynne, G. M.; Milne, T.; Russell, A.
10.1101/2020.12.18.423389 — cancer biology — Posted on 2020-12-18
1586 A human coronavirus evolves antigenically to escape antibody immunity
Eguia, R.; Crawford, K. H. D.; Stevens-Ayers, T.; Kelnhofer-Millevolte, L.; Greninger, A. L.; Englund, J. A.; Boeckh, M. J.; Bloom, J. D.
10.1101/2020.12.17.423313 — microbiology — Posted on 2020-12-18
1587 Cell-intrinsic IL4R alpha independence of large intestinal RELMα+ Ym1+ macrophages
Forman, R.; Logunova, L. B.; Smith, H.; Wenyss, K.; Mair, I.; Boon, L.; Allen, J. E.; Müller, W.; Pennock, J. L.; Else, K. J.
10.1101/2020.12.17.423033 — immunology — Posted on 2020-12-18
1589 Cortical recycling in high-level visual cortex during childhood development
Nordt, M.; Gomez, J.; Natu, V.; Rezai, A. A.; Finzi, D.; Kular, H.; Grill-Spector, K.
10.1101/2020.07.18.209783 — neuroscience — Posted on 2020-12-18
1591 Traces of transposable element in genome dark matter co-opted by flowering gene regulation networks.
Baud, A.; Wan, M.; Nouaud, D.; Francillonne, N.; Anxolabehere, D.; Quesneville, H.
10.1101/547877 — genomics — Posted on 2020-12-18
1593 De novo 3D models of SARS-CoV-2 RNA elements and small- molecule-binding RNAs to aid drug discovery
Rangan, R.; Watkins, A. M.; Chacon, J.; Kladwang, W.; Zheludev, I. N.; Townley, J.; Rynge, M.; Thain, G.; Das, R.
10.1101/2020.04.14.041962 — biochemistry — Posted on 2020-12-18
1595 The heterogeneous landscape and early evolution of pathogen-associated CpG dinucleotides in SARS-CoV-2
Di Gioacchino, A.; Sulc, P.; Komarova, A. V.; Greenbaum, B. D.; Monasson, R.; Cocco, S.
10.1101/2020.05.06.074039 — genomics — Posted on 2020-12-18
1596 Genetic evidence for a large overlap and potential bidirectional causal effects resilience and well-being.
de Vries, L. P.; Baselmans, B. M. L.; Luykx, J.; de Zeeuw, E. L.; Minica, C.; de Geus, E. J. C.; Vinkers, C. H.; Bartels, M.
10.1101/2020.11.03.366492 — genetics — Posted on 2020-12-18
1597 Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19
Tindle, C.; Fuller, M.; Fonseca, A.; Taheri, S.; Ibeawuchi, S.-R.; Beutler, N.; Claire, A.; Castillo, V.; Hernandez, M.; Russo, H.; Duran, J.; Crotty Alexander, L. E.; Tipps, A.; Lin, G.; Thistlethwaite, P. A.; Chattopadhyay, R.; Rogers, T. F.; Sahoo, D.; Ghosh, P.; Das, S.
10.1101/2020.10.17.344002 — cell biology — Posted on 2020-12-18
1598 Direct ex vivo gene expression profiling of malaria patients reveals common virulence gene expression in first-time infected patients and severe cases
Wichers, J. S.; Tonkin-Hill, G.; Thye, T.; Krumkamp, R.; Strauss, J.; von Thien, H.; Kreuels, B.; Scholz, J. A. M.; Smedegaard Hansson, H.; Jensen, R. W.; Turner, L.; Lorenz, F.-R.; Schoellhorn, A.; Bruchhaus, I.; Tannich, E.; Fendel, R.; Otto, T. D.; Lavstsen, T.; Gilberger, T. W.; Duffy, M. F.; Bachmann, A.
10.1101/2020.11.13.381137 — molecular biology — Posted on 2020-12-18
1600 Disparate temperature-dependent virus - host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium
V'kovski, P.; Gultom, M.; Kelly, J. N.; Steiner, S.; Russeil, J.; Mangeat, B.; Cora, E.; Pezoldt, J.; Holwerda, M.; Kratzel, A.; Laloli, L.; Wider, M.; Portmann, J.; Thao, T. T. N.; Ebert, N.; Stalder, H.; Hartmann, R.; Gardeux, V.; Alpern, D.; Deplancke, B.; Thiel, V.; Dijkman, R.
10.1101/2020.04.27.062315 — microbiology — Posted on 2020-12-18
1601 Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses
Morris, D. H.; Yinda, K. C. H.; Gamble, A.; Rossine, F. W.; Huang, Q.; Bushmaker, T.; Fischer, R. J.; Matson, M. J.; van Doremalen, N.; Vikesland, P. J.; Marr, L. C.; Munster, V.; Lloyd-Smith, J. O.
10.1101/2020.10.16.341883 — microbiology — Posted on 2020-12-18
1602 Immunological memory to SARS-CoV-2 assessed for up to eight months after infection
Dan, J. M.; Mateus, J.; Kato, Y.; Hastie, K. M.; Yu, E. D.; Faliti, C.; Grifoni, A.; Ramirez, S. I.; Haupt, S.; Frazier, A.; Nakao, C.; Rayaprolu, V.; Rawlings, S. A.; Peters, B.; Krammer, F.; Simon, V.; Saphire, E. O.; Smith, D.; Weiskopf, D.; Sette, A.; Crotty, S.
10.1101/2020.11.15.383323 — immunology — Posted on 2020-12-18
1603 Clinical connectome fingerprints of cognitive decline
Sorrentino, P.; Rucco, R.; Lardone, A.; Liparoti, M.; Troisi Lopez, E.; Cavaliere, C.; Soricelli, A.; Jirsa, V.; Sorrentino, G.; Amico, E.
10.1101/2020.10.09.332635 — neuroscience — Posted on 2020-12-18
1604 Infant functional connectivity fingerprints predict long-term language and pre-literacy outcomes
Yu, X.; Ferradal, S.; Sliva, D. D.; Dunstan, J.; Carruthers, C.; Sanfilippo, J.; Zuk, J.; Zollei, L.; Boyd, E.; Gagoski, B.; Grant, E. P.; Gaab, N.
10.1101/2020.10.29.360081 — neuroscience — Posted on 2020-12-18
1607 A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics
Gossen, J.; Albani, S.; Hanke, A.; Joseph, B. P.; Bergh, C.; Kuzikov, M.; Costanza, E.; Manelfi, C.; Storici, P.; Gribbon, P.; Beccari, A. R.; Talarico, C.; Spyrakis, F.; Lindahl, E.; Zaliani, A.; Carloni, P.; Wade, R. C.; Musiani, F.; Kokh, D. B.; Rossetti, G.
10.1101/2020.12.14.422634 — biophysics — Posted on 2020-12-18
1608 Multi-Level Attention Graph Neural Network for Clinically Interpretable Pathway-Level Biomarkers Discovery
Xing, X.; Yang, F.; Li, H.; Zhang, J.; Zhao, Y.; Jiang, B.; Huang, J.; Meng, M. Q.- H.; Yao, J.
10.1101/2020.12.03.409755 — bioinformatics — Posted on 2020-12-18
1612 Existence and Features of the Myodural Bridge in Gentoo Penguins: a morphological study
Chen, C.; Yu, S.-b.; Chi, Y.-y.; Tan, G.-y.; Yan, B.-c.; Zheng, N.; Sui, H.-J.
10.1101/2020.12.17.423215 — zoology — Posted on 2020-12-17
1613 ZIKV disrupts fetal outcome, placental ultrastructure and drug transporter expression in mice
Andrade, C. B. V.; Monteiro, V. R. S.; Coelho, S. V. A.; Gomes, H. R.; Sousa, R. P. C.; Nascimento, V. M. O.; Bloise, F. F.; Matthews, S. G.; Bloise, E.; Arruda, L. B.; Ortiga-Carvalho, T. M.
10.1101/2020.12.17.423218 — physiology — Posted on 2020-12-17
1618 Preventive training interferes with mRNA-encoding myosin 7 and collagen I expression during pulmonary arterial hypertension
Mariano, T. B.; de Souza Castilho, A. C.; de Almeida Sabela, A. K. D.; de Oliveira, A. C.; Cury, S. S.; Aguiar, A. F.; Dias, R. d. J. D.; Cicogna, A. C.; Okoshi, K.; Junior, L. A. J.; Carvalho, R. F.; Pacagnelli, F.
10.1101/2020.12.17.423207 — molecular biology — Posted on 2020-12-17
1619 Identification of Celastrol as a novel HIV-1 Latency Reversal Agent by an Image-Based Screen
Rice, A. P.; Liu, H.; Hu, P.-W. P.; Dubrulle, J. P.; Stossi, F.; Mancini, M.; Nikolai, B.
10.1101/2020.12.17.423211 — microbiology — Posted on 2020-12-17
1620 Poly(ADP-ribose) potentiates ZAP antiviral activity
Pornillos, O.; Xue, G.; Braczyk, K.; Goncalves-Carneiro, D.; Ong, H.; Dawidziak, D. M.; Zawada, K.; Yueping, W.; Zadrozny, K. K.; Ganser-Pornillos, B. K.; Bieniasz, P. D.
10.1101/2020.12.17.423219 — microbiology — Posted on 2020-12-17
1622 Host protection to intestinal worm infections: the importance of activated and armed innate effector cells at the host parasite interface.
Ariyaratne, A.; Kim, S. Y.; Pollo, S. M. J.; de Cassia Luzzi, M.; Bowron, J.; Szabo, E.; Wasmuth, J. D.; Nair, M. G.; Finney, C. A. M.
10.1101/2020.12.17.423220 — immunology — Posted on 2020-12-17
1623 Exosomal miR-224 contributes to hemolymph microbiota homeostasis during bacterial infection in crustacean
Gong, Y.; Wei, X.; Sun, W.; Ren, X.; Chen, J.; Aweya, J. J.; Ma, H.; Chan, K.-G.; Zhang, Y.; Li, S.
10.1101/2020.12.17.423222 — immunology — Posted on 2020-12-17
1624 Identification of a novel conserved signaling motif in CD200 Receptor required for its inhibitory function
Timmerman, L. M.; de Graaf, J. F.; Satravelas, N.; Kesmir, C.; Meyaard, L.; van der Vlist, M.
10.1101/2020.12.17.423210 — immunology — Posted on 2020-12-17
1626 Human hippocampal neurons track moments in a sequence of events.
Reddy, L.; Zoefel, B.; Possel, J.; Peters, J.; Dijksterhuis, D.; Poncet, M.; van Straaten, E. C. W.; Baayen, J. C.; Idema, S.; Self, M. W.
10.1101/2020.12.17.423193 — neuroscience — Posted on 2020-12-17
1627 A unified theory of E/I synaptic balance, quasicritical neuronal avalanches and asynchronous irregular spiking
Girardi-Schappo, M.; Galera, E. F.; Carvalho, T. T. A.; Brochini, L.; Kamiji, N. L.; Roque, A. C.; Kinouchi, O.
10.1101/2020.12.17.423201 — neuroscience — Posted on 2020-12-17
1628 A MYT1L Syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
Chen, J.; Lambo, M. E.; Xia, G.; Dearborn, J. T.; Liu, Y.; McCullough, K. B.; Swift, R. G.; Tabachnick, D. R.; Tian, L.; Noguchi, K.; Garbow, J. R.; Gabel, H. W.; Hengen, K. B.; Maloney, S. E.; Dougherty, J. D.
10.1101/2020.12.17.423095 — neuroscience — Posted on 2020-12-17
1631 Altered functional brain dynamics in chromosome 22q11.2 deletion syndrome during facial affect processing
Cornblath, E. J.; Mahadevan, A. S.; He, X.; Ruparel, K.; Lydon-Staley, D. M.; Moore, T. M.; Gur, R. C.; Zackai, E. H.; Emanuel, B.; McDonald-McGinn, D. M.; Wolf, D. H.; Satterthwaite, T. D.; Roalf, D. R.; Gur, R. E.; Bassett, D. S.
10.1101/2020.12.17.423342 — neuroscience — Posted on 2020-12-17
1638 Fly stage trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in near physiological conditions
Villafraz, O.; Biran, M.; Pineda, E.; Plazolles, N.; Cahoreau, E.; Ornitz, R.; Magali, T.; Allmann, S.; Tetaud, E.; Riviere, L.; Silber, A.; Barrett, M. P.; Zikova, A.; Boshart, M.; Portais, J.-C.; Bringaud, F.
10.1101/2020.12.17.423221 — microbiology — Posted on 2020-12-17
1639 Eliminating accidental deviations to minimize generalization error and maximize reliability: applications in connectomics and genomics
Bridgeford, E. W.; Wang, S.; Yang, Z.; Wang, Z.; Xu, T.; Craddock, C.; Dey, J.; Kiar, G.; Gray-Roncal, W.; Coulantoni, C.; Douville, C.; Priebe, C. E.; Caffo, B.; Milham, M.; Zuo, X.-N.; Consortium for Reliability and Reproducibility, ; Vogelstein, J. T.
10.1101/802629 — neuroscience — Posted on 2020-12-17
1640 Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas
Bonglack, E. N.; Messinger, J. E.; Cable, J. M.; Parnell, M.; Ch'ng, J.; Christofk, H. R.; Luftig, M. A.
10.1101/2020.12.04.410563 — cancer biology — Posted on 2020-12-17
1643 Biodiversity Soup II: A bulk-sample metabarcoding pipeline emphasizing error reduction
Yang, C.; Bohmann, K.; Wang, X.; Cai, W.; Wales, N.; Ding, Z.; Gopalakrishnan, S.; Yu, D. W.
10.1101/2020.07.07.187666 — ecology — Posted on 2020-12-17
1648 Intracellular sterol sensing controls intestinal B cell differentiation
Trindade, B. C.; Ceglia, S.; Berthelette, A.; Raso, F.; Howley, K.; Muppidi, J. R.; Reboldi, A.
10.1101/2020.11.03.367177 — immunology — Posted on 2020-12-17
1649 A Population Receptive Field Model of the Magnetoencephalography Response
Kupers, E. R.; Edadan, A.; Benson, N. C.; Zuiderbaan, W.; De Jong, M. C.; Dumoulin, S. O.; Winawer, J.
10.1101/2020.08.28.272534 — neuroscience — Posted on 2020-12-17
1650 Predicting cell health phenotypes using image-based morphology profiling
Way, G. P.; Kost-Alimova, M.; Shibue, T.; Harrington, W. F.; Gill, S.; Piccioni, F.; Becker, T.; Shafqat-Abbasi, H.; Hahn, W. C.; Carpenter, A. E.; Vazquez, F.; Singh, S.
10.1101/2020.07.08.193938 — bioinformatics — Posted on 2020-12-17
1651 Master Transcription Factors Regulate the DNA Methylation Landscape During Hepatocyte Differentiation
Suzuki, T.; Furuhata, E.; Maeda, S.; Kishima, M.; Miyajima, Y.; Tanaka, Y.; Lim, J.; Nishimura, H.; Nakanishi, Y.; Shojima, A.; Suzuki, H.
10.1101/2020.12.16.423165 — genomics — Posted on 2020-12-17
1653 Evolutionarily Driven Domain Swap Alters Sigma Factor Dependence in Bacterial Signaling System
Garber, M. E.; Frank, V.; Kazakov, A. E.; Zhang, H.; Incha, M. R.; Keasling, J. D.; Rajeev, L.; Mukhopadhyay, A.
10.1101/2020.09.30.321588 — evolutionary biology — Posted on 2020-12-17
1656 Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells.
Hooikaas, P. J.; Damstra, H. G. J.; Gros, O. J.; van Riel, W. E.; Martin, M.; Smits, Y. T. H.; van Loosdregt, J.; Kapitein, L. C.; Berger, F.; Akhmanova, A.
10.1101/2020.08.28.271643 — cell biology — Posted on 2020-12-17
1657 DOCK5 stabilises the leading edge in migrating cells to promote YAP/TAZ activation.
Pascual-Vargas, P. P.; Arias-Garcia, M.; Roumeliotis, T. I.; Chaudhary, J. S.; Bakal, C.
10.1101/2020.07.24.218313 — cell biology — Posted on 2020-12-17
1658 Epilepsy kinase CDKL5 is a DNA damage sensor which controls transcriptional activity at DNA breaks
Khanam, T.; Munoz, I.; Weiland, F.; Carroll, T.; Borsos, B. N.; Pantazi, V.; Slean, M.; Novak, M.; Toth, R.; Appleton, P.; Pankotai, T.; Zhou, H.; Rouse, J.
10.1101/2020.12.10.419747 — cell biology — Posted on 2020-12-17
1661 Do initial concentration and activated sludge seasonality affect pharmaceutical biodegradation rate constants?
van Bergen, T. J. H. M.; Rios-Miguel, A. B.; Nolte, T. M.; Ragas, A. M.; van Zelm, R.; Graumans, M. H.; Scheepers, P. T.; Jetten, M. S.; Hendriks, A. J.; Welte, C. U.
10.1101/2020.12.17.423224 — microbiology — Posted on 2020-12-17
1664 The self-peptide repertoire plays a critical role in transplant tolerance induction
Son, E. T.; Faridi, P.; Paul-Heng, M.; Leong, M.; English, K.; Ramarathinam, S. H.; Braun, A.; Dudek, N.; Alexander, I. E.; Lisowski, L.; Bertolino, P.; Bowen, D.; Purcell, A. W.; Mifsud, N.; Sharland, A. F.
10.1101/2020.11.09.359968 — immunology — Posted on 2020-12-17
1665 Connectome subgraph isomorphisms and graph queries
Matelsky, J. K.; Reilly, E. P.; Johnson, E. C.; Wester, B. A.; Gray-Roncal, W.
10.1101/2020.06.08.140533 — neuroscience — Posted on 2020-12-17
1667 Genotype-phenotype map of an RNA-ligand complex
Puchta, O.; Sobczyk, G.; Smer-Barreto, V.; Ireland, H.; Vendrell, M.; Oyarzun, D. A.; Bujnicki, J. M. A.; Whyte, G.; Kudla, G.
10.1101/2020.12.17.423258 — synthetic biology — Posted on 2020-12-17
1668 Deep Learning Identification of Stiffness Markers in Breast Cancer
Sneider, A.; Kim, J. H.; Kiemen, A.; Wu, P.-H.; Habibi, M.; White, M.; Phillip, J. M.; Gu, L.; Wirtz, D.
10.1101/2020.12.17.423077 — cancer biology — Posted on 2020-12-17
1670 Molecular diversity analysis of the spike glycoprotein (S) gene from Hong Kong - China
Da Silva, E. D. A. B.; Venancio, D. B. R.; Albuquerque, R. M. d.; Ramos, R. d. S.; Felix, P. T.
10.1101/2020.12.16.423166 — bioinformatics — Posted on 2020-12-17
1671 Data structures based on k-mers for querying large collections of sequencing datasets
Marchet, C.; Boucher, C.; Puglisi, S. J.; Medvedev, P.; Salson, M.; Chikhi, R.
10.1101/866756 — bioinformatics — Posted on 2020-12-17
1672 RAD51AP1 mediates RAD51 activity through nucleosome interaction
Pires, E.; Sharma, N.; Selemenakis, P.; Wu, B.; Huang, Y.; Zhao, W.; Wiese, C.
10.1101/2020.12.17.421636 — biochemistry — Posted on 2020-12-17
1676 Seasonal niche differentiation between evolutionary closely related marine bacteria
Auladell, A.; Barberan, A.; Logares, R.; Garces, E.; Gasol, J. M.; Ferrera, I.
10.1101/2020.12.17.423265 — microbiology — Posted on 2020-12-17
1678 Temporal Shifts in Antibiotic Resistance Elements Govern Virus-Pathogen Conflicts
LeGault, K.; Hays, S. G.; Angermeyer, A.; McKitterick, A. C.; Johura, F.-t.; Sultana, M.; Alam, M.; Seed, K. D.
10.1101/2020.12.16.423150 — microbiology — Posted on 2020-12-17
1682 NirA is an alternative nitrite reductase from Pseudomonas aeruginosa with potential as an anti-virulence target
Fenn, S. J.; Dubern, J.-F.; Cigana, C.; Simone, M. D.; Lazenby, J.; Juhas, M.; Schwager, S.; Bianconi, I.; Döring, G.; Elmsley, J.; Eberl, L.; Williams, P.; Brangonzi, A.; Camara, M.
10.1101/2020.12.17.423290 — microbiology — Posted on 2020-12-17
1683 Soil Chemistry and Microbiome Determine N2O Emission Potential in Soils
Highton, M.; Bakken, L. R.; Dorsch, P.; Tobias-Hunefeldt, S.; Molstad, L.; Morales, S. E.
10.1101/2020.12.16.422796 — microbiology — Posted on 2020-12-17
1684 Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses
Llibre, A.; Smith, N.; Rouilly, V.; Musvosvi, M.; Nemes, E.; Posseme, C.; Mabwe, S.; Charbit, B.; Kimbung Mbandi, S.; Filander, E.; Africa, H.; Saint-Andre, V.; Bondet, V.; Bost, P.; Mulenga, H.; Bilek, N.; Albert, M. L.; Scriba, T. J.; Duffy, D.
10.1101/2020.12.17.423082 — immunology — Posted on 2020-12-17
1685 A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins
Lazar, N.; Mesarich, C. H.; Petit-Houdenot, Y.; Talbi, N.; Li de la Sierra-Gallay, I.; Zelie, E.; Blondeau, K.; Gracy, J.; Ollivier, B.; Blaise, F.; Rouxel, T.; Balesdent, M.-H.; Idnurm, A.; van Tilbeurgh, H.; Fudal, I.
10.1101/2020.12.17.423041 — plant biology — Posted on 2020-12-17
1687 Monitoring Reactivation of Latent HIV by Label-Free Gradient Light Interference Microscopy
Goswami, N.; Lu, Y.; Kandel, M. E.; Fanous, M. J.; Bohn-Wippert, K.; Tevonian, E. N.; Dar, R. D.; Popescu, G.
10.1101/2020.12.16.423158 — bioengineering — Posted on 2020-12-17
1689 Cohesin regulates homology search during recombinational DNA repair
Piazza, A.; Bordelet, H.; Dumont, A.; Thierry, A.; Savocco, J.; Girard, F.; Koszul, R.
10.1101/2020.12.17.423195 — genetics — Posted on 2020-12-17
1692 Activation of the type 3 secretion system of enteropathogenic E. coli leads to reprogrammingof its lipid metabolism
Zacharia, A.; Pal, R. R.; Katsowich, N.; Mannully, C. T.; Alfandary, S.; Serruya, R.; Baidya, A.; Ben-Yehuda, S.; Rosenshine, I.; Moussaieff, A.
10.1101/2020.12.17.423234 — microbiology — Posted on 2020-12-17
1694 Ageing and MPTP-sensitivity depend on molecular and ultrastructural signatures of astroglia and microglia in mice nigra
Abhilash, P.; Bharti, U.; Haorei, Y.; Rashmi, S.; Raju, T. R.; Kutty, B. M.; Chandrashekar Sagar, B.; Alladi, P. A.
10.1101/2020.12.15.422212 — neuroscience — Posted on 2020-12-17
1695 scCODA: A Bayesian model for compositional single-cell data analysis
Buettner, M.; Ostner, J.; Mueller, C. L.; Theis, F. J.; Schubert, B.
10.1101/2020.12.14.422688 — bioinformatics — Posted on 2020-12-17
1697 Environmental interactions with amoebae as drivers of bacterial-fungal endosymbiosis and pathogenicity
Itabangi, H.; Sephton-Clark, P.; Zhou, X.; Starling, G. P.; Mahamoud, Z.; Insua, I.; Probert, M.; Correia, J.; Moynihan, P.; Gu, Y.; Gebremariam, T.; Ibrahim, A. S.; Brown, G. D.; King, J. S.; Ballou, E. R.; Voelz, K.
10.1101/584607 — microbiology — Posted on 2020-12-17
1698 Median/modal death ages of pooled European male cohorts were near-constant for ~25/30 years.
Clark, J. S. C.; Rydzewska, K.; Podsiadlo, K.; van de Wetering, T.; Ciechanowicz, A.
10.1101/2020.05.23.111971 — physiology — Posted on 2020-12-17
1700 Motor planning modulates neural activity patterns in early human auditory cortex
Gale, D. J.; Areshenkoff, C. N.; Honda, C. T.; Johnsrude, I. S.; Flanagan, J. R.; Gallivan, J. P.
10.1101/682609 — neuroscience — Posted on 2020-12-17
1701 Phylogenomic Discordance in the Eared Seals is best explained by Incomplete Lineage Sorting following Explosive Radiation in the Southern Hemisphere
Lopes, F.; Oliveira, L. R.; Kessler, A.; Beux, Y.; Crespo, E.; Cardenas-Alayza, S.; Majluf, P.; Sepulveda, M.; Brownell, R. L.; Franco-Trecu, V.; Paez-Rosas, D.; Chaves, J.; Loch, C.; Robertson, B.; Acevedo-Whitehouse, K.; Elorriaga-Verplancken, F. R.; Kirkman, S. P.; Peart, C. R.; Wolf, J. B. W.; Bonatto, S. L.
10.1101/2020.08.11.246108 — evolutionary biology — Posted on 2020-12-17
1704 Single-nuclei RNA-sequencing of plants
Sunaga-Franze, D. Y.; Muino, J.; Braeuning, C.; Xu, X.; Zong, M.; Smaczniak, C.; Yan, W.; Fischer, C.; Vidal, R.; Kliem, M.; Kaufmann, K.; Sauer, S.
10.1101/2020.11.14.382812 — genomics — Posted on 2020-12-17
1706 Patterns of gene flow across multiple anthropogenic infrastructures: insights from a multi-species approach
Remon, J.; Moulherat, S.; Cornuau, J. H.; Gendron, L.; Richard, M.; Baguette, M.; Prunier, J. G.
10.1101/2019.12.16.877670 — ecology — Posted on 2020-12-17
1707 DOCK5 stabilises the leading edge in migrating cells to promote YAP/TAZ activation.
Pascual-Vargas, P. P.; Arias-Garcia, M.; Roumeliotis, T. I.; Chaudhary, J. S.; Bakal, C.
10.1101/2020.07.24.218313 — cell biology — Posted on 2020-12-17
1708 Upregulated-flotillins and sphingosine kinase 2 derail vesicular trafic to stabilize AXL and promote epithelial-mesenchymal transition
Genest, M.; Comunale, F.; Planchon, D.; Govindin, P.; Vacher, S.; Bieche, I.; Robert, B.; Malhotra, H.; Schoenit, A.; Tashireva, L.; Gauthier-Rouviere, C.; Bodin, S.
10.1101/2020.05.12.090571 — cell biology — Posted on 2020-12-17
1709 Human cytomegalovirus infection changes the pattern of surface markers of small extracellular vesicles isolated from first trimester placental histocultures
Bergamelli, M.; Martin, H.; Benard, M.; Ausseil, J.; Mansuy, J.-M.; Hurbain, I.; Mouysset, M.; Groussolles, M.; Cartron, G.; Tanguy le Gac, Y.; Moinard, N.; Suberbielle, E.; Izopet, J.; Tscherning, C.; Raposo, G.; Gonzalez-Dunia, D.; D'Angelo, G.; Malnou, C. E.
10.1101/2020.11.30.402693 — cell biology — Posted on 2020-12-17
1710 BCKDK regulates the TCA cycle through PDC to ensure embryonic development in the absence of PDK family
Heinemann-Yerushalmi, L.; Bentovim, L.; Felsenthal, N.; Vinestock, R. C.; Michaeli, N.; Krief, S.; Silberman, A.; Cohen, M.; Ben-Dor, S.; Brenner, O.; Haffner-Krausz, R.; Itkin, M.; Malitsky, S.; Erez, A.; Zelzer, E.
10.1101/2020.03.22.002360 — molecular biology — Posted on 2020-12-17
1712 Niche and local geography shape the pangenome of wastewater- and livestock-associated Enterobacteriaceae
Shaw, L. P.; Chau, K. K.; Kavanagh, J.; AbuOun, M.; Stubberfield, E.; Gweon, H. S.; Barker, L.; Rodger, G.; Bowes, M. J.; Hubbard, A. T. M.; Pickford, H.; Swann, J.; Gilson, D.; Smith, R. P.; Hoosdally, S. J.; Sebra, R.; Brett, H.; Peto, T. E. A.; Bailey, M. J.; Crook, D. W.; Read, D. S.; Anjum, M. F.; Walker, A. S.; Stoesser, N.; REHAB consortium,
10.1101/2020.07.23.215756 — microbiology — Posted on 2020-12-17
1713 Temporal complexity of fMRI is reproducible and correlates with higher order cognition
Omidvarnia, A.; Zalesky, A.; Mansour, S.; Van De Ville, D.; Jackson, G.; Pedersen, M.
10.1101/770826 — neuroscience — Posted on 2020-12-17
1715 Muscle Van Gogh-like 2 shapes the neuromuscular synapse by regulating MuSK signaling activity
Boex, M.; Messeant, J.; Cottin, S.; Halliez, M.; Bauche, S.; Buon, C.; Sans, N.; montcouquiol, m.; Molgo, J.; Amar, M.; Ferry, A.; Lemaitre, M.; Rouche, A.; Langui, D.; Baskaran, A.; Fontaine, B.; Strochlic, L.
10.1101/2020.11.26.384925 — neuroscience — Posted on 2020-12-17
1716 An immersive first-person navigation task for abstract knowledge acquisition
Kuhrt, D.; St. John, N. R.; Bellmund, J. L. S.; Kaplan, R.; Doeller, C. F.
10.1101/2020.07.17.208900 — neuroscience — Posted on 2020-12-17
1717 Self-beneficial belief updating as a coping mechanism for stress-induced negative affect
Czekalla, N.; Baumann, J.; Stolz, D. S.; Mayer, A. V.; Voges, J. F.; Rademacher, L.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.
10.1101/2020.12.02.408096 — neuroscience — Posted on 2020-12-17
1718 Safe and easy evaluation of tmRNA-SmpB-mediated trans-translation in ESKAPE pathogenic bacteria
Thepaut, M.; Campos Da Silva, R.; Renard, E.; Barloy-Hubler, F.; Ennifar, E.; Boujard, D.; Gillet, R.
10.1101/2020.12.16.423090 — biochemistry — Posted on 2020-12-17
1719 Genomic Surveillance of Neisseria gonorrhoeae in the Philippines 2013-2014
Jamoralin, M. C.; Argimon, S.; Lagrada, M. L.; Villamin, A. S.; Masim, M. L.; Gayeta, J. M.; Boehme, K. D.; Olorosa, A. M.; Sia, S. B.; Hufano, C. M.; Cohen, V.; Hernandez, L. T.; Jeffrey, B.; Abudahab, K.; Stelling, J.; Holden, M. T. G.; Aanensen, D. M.; Carlos, C. C.; on behalf of the Philippines Antimicrobial Resistance Surveillance Program,
10.1101/2020.03.19.998435 — genomics — Posted on 2020-12-17
1720 Relevance of Antibodies against the Chicken Anaemia Virus
Ingberman, M.; Caron, L. F.; Rigo, F.; Araujo, L. C.; de Almeida, M. A. P.; Dal Berto, L.; Beirao, B. C. B.
10.1101/2020.12.15.422992 — immunology — Posted on 2020-12-17
1723 SUMO-specific protease 2 (SENP2) suppresses browning of white adipose tissue through C/EBPβ modulation
Lee, J. S.; Chae, S.; Nan, J.; Koo, Y. D.; Lee, S.-A.; Park, Y. J.; Hwang, D.; Han, W.; Kim, Y.-B.; Chung, S. S.; Park, K. S.
10.1101/2020.12.16.422969 — cell biology — Posted on 2020-12-17
1726 Modulation of the primary auditory thalamus when recognising speech with background noise
Mihai, P. G.; Moerel, M.; de Martino, F.; Trampel, R.; Kiebel, S.; von Kriegstein, K.
10.1101/510164 — neuroscience — Posted on 2020-12-17
1728 Experimental evolution to identify undescribed mechanisms of resistance to a novel cationic peptide antibiotic
Santos Lopez, A.; Fritz, M. J.; Lombardo, J.; Burr, A. H.; Heinrich, V. A.; Marshall, C. W.; Cooper, V. S.
10.1101/2020.12.16.423161 — microbiology — Posted on 2020-12-16
1729 Neural correlates of interpersonal space permeability and flexibility in autism spectrum disorder
Massaccesi, C.; Groessing, A.; Rosenberger, L. A.; Hartmann, H.; Candini, M.; di Pellegrino, G.; Frassinetti, F.; Silani, G.
10.1101/2020.10.14.339291 — neuroscience — Posted on 2020-12-17
1730 Intron retention as a new marker of the pre-disease state and its recovery to the normal state by a traditional Japanese multi-herbal medicine
Okada, N.; Oshima, K.; Iwasaki, Y.; Maruko, A.; Matsumura, K.; Iioka, E.; Vu, T.-D.; Fujitsuka, N.; Nishi, A.; Sugiyama, A.; Nishiyama, M.; Kaneko, A.; mizoguchi, k.; Yamamoto, M.; Nishimura, S.
10.1101/2020.02.10.941435 — molecular biology — Posted on 2020-12-16
1731 APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis
Ramakrishna, S.; Jhaveri, V.; Konings, S. C.; Chakraborty, S.; Holst, B.; Schmid, B.; Gouras, G. K.; Freude, K. K.; Muddashetty, R. S.
10.1101/2020.12.10.418772 — neuroscience — Posted on 2020-12-16
1732 Quantification reveals early dynamics in Drosophila maternal gradients
Shlemov, A.; Alexandrov, T.; Golyandina, N.; Holloway, D.; Baumgartner, S.; Spirov, A. V.
10.1101/2020.12.16.423027 — systems biology — Posted on 2020-12-16
1733 Analysis of human mitochondrial genome co-occurrence networks of Asian population at varying altitudes
Verma, R. K.; Kalyakuina, A.; Giuliani, C.; Shinde, P.; Kachhvah, A. D.; Ivanchenko, M.; Jalan, S.
10.1101/2019.12.21.885905 — systems biology — Posted on 2020-12-16
1734 Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
Kim, J. H.; Megquier, K. J.; Thomas, R.; Sarver, A. L.; Song, J. M.; Kim, Y. T.; Schulte, A. J.; Cheng, N.; Linden, M. A.; Murugan, P.; Oseth, L.; Foster, C. L.; Elvers, I.; Swofford, R.; Turner-Maier, J.; Karlsson, E. K.; Breen, M.; Lindblad-Toh, K.; Modiano, J. F.
10.1101/2020.08.11.246777 — cancer biology — Posted on 2020-12-16
1735 Atomistic Basis of Force Generation, Translocation, and Coordination in a Viral Genome Packaging Motor
Pajak, J.; Dill, E.; Reyes-Aldrete, E.; White, M. A.; Kelch, B. A.; Jardine, P.; Arya, G.; Morais, M. C.
10.1101/2020.07.27.223032 — biophysics — Posted on 2020-12-16
1739 Persistence as an optimal hedging strategy
Browning, A. P.; Sharp, J. A.; Mapder, T.; Baker, C. M.; Burrage, K.; Simpson, M. J.
10.1101/2019.12.19.883645 — systems biology — Posted on 2020-12-16
1741 Effects of physiological deficits in pineal melatonin on Triple Negative Breast Cancer.
Dearing, C. G.; Silva, P. D.; Turner, D. N.; Fish, B. A.; Contreras, E. O.; Schwarting, Z. A.; Sena, J.; Schilkey, F. D.; Bearer, E. L.; Wilkinson, S. D.; Rogelj, S. O.; Thompson, S.
10.1101/2020.12.16.423028 — cancer biology — Posted on 2020-12-16
1746 Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity and an important role for transcriptional and translational control
Andersson, S.; Romero, A.; Rodrigues, J. I.; Hua, S.; Hao, X.; Jacobson, T.; Karl, V.; Becker, N.; Ashouri, A.; Nyström, T.; Liu, B.; Tamas, M. J.
10.1101/2020.12.16.423032 — cell biology — Posted on 2020-12-16
1750 Global gene-expression analysis reveals the molecular processes underlying ClC-5 loss-of-function in novel Dent Disease 1 cellular models
Duran, M.; Burballa, C.; Cantero-Recasens, G.; Butnaru, C.; Malhotra, V.; Ariceta, G.; Sarro, E.; Meseguer, A.
10.1101/2020.12.16.423143 — pathology — Posted on 2020-12-16
1751 Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast
Bordeaux, E. K.; Sottnik, J. L.; Mehrotra, S.; Ferrara, S. E.; Goodspeed, A. E.; Costello, J. C.; Sikora, M. J.
10.1101/2020.12.16.423142 — cancer biology — Posted on 2020-12-16
1752 A Chameleonic Macrocyclic Peptide with Drug Delivery Applications
Payne, C. D.; Franke, B.; Fisher, M. F.; Hajiaghaalipour, F.; McAleese, C. E.; Song, A.; Eliasson, C.; Zhang, J.; Jayasena, A.; Vadlamani, G.; Clark, R. J.; Minchin, R. F.; Mylne, J. S.; Rosengren, K. J.
10.1101/2020.12.16.422786 — biochemistry — Posted on 2020-12-16
1753 Eleven biosynthetic genes explain the majority of natural variation for carotenoid levels in maize grain
Diepenbrock, C. H.; Ilut, D. C.; Magallanes-Lundback, M.; Kandianis, C. B.; Lipka, A. E.; Bradbury, P. J.; Holland, J. B.; Hamilton, J. P.; Wooldridge, E.; Vaillancourt, B.; Gongora-Castillo, E.; Wallace, J. G.; Cepela, J.; Mateos-Hernandez, M.; Owens, B. F.; Tiede, T.; Buckler, E. S.; Rocheford, T.; Buell, C. R.; Gore, M. A.; DellaPenna, D.
10.1101/2020.07.15.203448 — genetics — Posted on 2020-12-16
1754 Bacterial density as an unexpected factor regulating decomposition by soil oligotrophs
Coche, A.; Babey, T.; Rapaport, A.; Vieuble Gonod, L.; Garnier, P.; Nunan, N.; de Dreuzy, J. R.
10.1101/2020.11.16.384735 — ecology — Posted on 2020-12-16
1757 3D FIB-SEM reconstruction of microtubule-organelle interaction in whole primary mouse beta cells
Mueller, A.; Schmidt, D.; Xu, C. S.; Pang, S.; D'Costa, J. V.; Kretschmar, S.; Muenster, C.; Kurth, T.; Jug, F.; Weigert, M.; Hess, H. F.; Solimena, M.
10.1101/2020.10.07.329268 — cell biology — Posted on 2020-12-16
1759 Methylation of Dual Specificity Phosphatase 4 Controls Cell Differentiation
Su, H.; Jiang, M.; Senevirathne, C.; Aluri, S.; Zhang, T.; Guo, H.; Xavier-Ferrucio, J.; Jin, S.; Tran, N.-T.; Liu, S.-M.; Sun, C.-W.; Zhu, Y.; Zhao, Q.; Chen, Y.; Cable, L.; Shen, Y.; Liu, J.; Qu, C.-K.; Han, X.; Klug, C. A.; Bhatia, R.; Chen, Y.; Nimer, S. D.; Zheng, Y. G.; Iancu-Rubin, C.; Jin, J.; Deng, H.; Krause, D. S.; Xiang, J.; Verma, A.; Luo, M.; Zhao, X.
10.1101/2020.12.16.422727 — cell biology — Posted on 2020-12-16
1762 Major threats to a migratory raptor vary geographically along the eastern Mediterranean flyway
Oppel, S.; Arkumarev, V.; Bakari, S.; Dobrev, V.; Saravia, V.; Adefolu, S.; Aktay Sozuer, L.; Apeverga, P. T.; Arslan, S.; Barshep, Y.; Bino, T.; Bounas, A.; Cetin, T.; Dayyoub, M.; Dobrev, D.; Duro, K.; El-Moghrabi, L.; ElSafoury, H.; Endris, A.; Ghazal Asswad, N.; Harry, J. H.; Ivande, S. T.; Jbour, S.; Kapsalis, E.; Kret, E.; Mahamued, B. A.; Manu, S. A.; Mengistu, S.; Moussa Zabeirou, A. R.; Muhammad, S. I.; Nakev, S.; Ngari, A.; Onoja, J.; Osta, M.; Ozuslu, S.; Petrovski, N.; Popgeorgiev, G.; Pourchier, C.; Ruffo, A.; Shobrak, M.; Sidiropoulos, L.; Skartsi, T.; Sozuer, O.; Stara, K.; Tesf
10.1101/2020.12.16.422983 — zoology — Posted on 2020-12-16
1764 The secreted hypersensitive response inducing protein 1 from Botrytis cinerea displays non-canonical PAMP-activity
Jeblick, T.; Leisen, T.; Steidele, C. E.; Mueller, J.; Mahler, F.; Sommer, F.; Keller, S.; Hueckelhoven, R.; Hahn, M.; Scheuring, D.
10.1101/2020.12.16.423131 — plant biology — Posted on 2020-12-16
1766 A native chemical chaperone in the human eye lens
Serebryany, E.; Chowdhury, S.; Watson, N. E.; McClelland, A.; Shakhnovich, E. I.
10.1101/2020.12.16.423154 — biophysics — Posted on 2020-12-16
1769 Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
Liu, P.; Liang, S.; Zheng, C.; Mintzer, E.; Zhao, Y. G.; Ponnienselvan, K.; Mir, A.; Sontheimer, E. J.; Gao, G.; Flotte, T. R.; Wolfe, S.; Xue, W.
10.1101/2020.12.15.422970 — bioengineering — Posted on 2020-12-16
1770 A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at Pathogenwatch
Argimon, S.; Yeats, C. A.; Goater, R. J.; Abudahab, K.; Taylor, B.; Underwood, A.; Sanchez-Buso, L.; Wong, V. K.; Dyson, Z. A.; Nair, S.; Park, S. E.; Marks, F.; Page, A. J.; Keane, J. A.; Baker, S.; Holt, K. E.; Dougan, G.; Aanensen, D. M.
10.1101/2020.07.03.186692 — genomics — Posted on 2020-12-16
1771 Genetic variation for plant growth traits in a common wheat population is dominated by known variants and novel QTL
DeWitt, N.; Guedira, M.; Lauer, E.; Murphy, J. P.; Marshall, D.; Mergoum, M.; Johnson, J.; Holland, J. B.; Brown-Guedira, G.
10.1101/2020.12.16.422696 — genetics — Posted on 2020-12-16
1772 Large-scale association analyses identify host factors influencing human gut microbiome composition
Kurilshikov, A.; Medina-Gomez, C.; Bacigalupe, R.; Radjabzadeh, D.; Wang, J.; Demirkan, A.; Le Roy, C. I.; Raygoza Garay, J. A.; Finnicum, C.; Liu, X.; Zhernakova, D.; Bonder, M. J.; Hansen, T. H.; Frost, F.; Ruhlemann, M. C.; Turpin, W.; Moon, J.-Y.; Kim, H.-N.; Lull, K.; Barkan, E.; Shah, S. A.; Fornage, M.; Szopinska-Tokov, J.; Wallen, Z.; Borisevich, D.; Agreus, L.; Andreasson, A.; Bang, C.; Bedrani, L.; Bell, J. T.; Bisgaard, H.; Boehnke, M.; Boomsma, D. I.; Burk, R. D.; Claringbould, A.; Croitoru, K.; Davies, G.; Van Duijn, C.; Duijts, L.; Falony, G.; Fu, J.; van der Graaf, A.; Hansen, T
10.1101/2020.06.26.173724 — genetics — Posted on 2020-12-16
1773 Pleiotropy and Epistasis Within and Between Signaling Pathways Defines the Genetic Architecture of Fungal Virulence
Roth, C. J. N.; Murray, D.; Scott, A.; Fu, C.; Averette, A. F.; Sun, S.; Heitman, J.; Magwene, P. M.
10.1101/2020.08.21.259861 — genetics — Posted on 2020-12-16
1776 The Ceratodon purpureus genome uncovers structurally complex, gene rich sex chromosomes
Carey, S. B.; Jenkins, J.; Lovell, J. T.; Maumus, F.; Sreedasyam, A.; Payton, A. C.; Shu, S.; Tiley, G. P.; Fernandez-Pozo, N.; Barry, K.; Chen, C.; Wang, M.; Lipzen, A.; Daum, C.; Saski, C. A.; McBreen, J. C.; Conrad, R. E.; Kollar, L. M.; Olsson, S.; Huttunen, S.; Landis, J. B.; Burleigh, G.; Wickett, N. J.; Johnson, M. G.; Rensing, S. A.; Grimwood, J.; Schmutz, J.; McDaniel, S.
10.1101/2020.07.03.163634 — evolutionary biology — Posted on 2020-12-16
1778 Axial Elongation of Caudalized Human Organoids Mimics Neural Tube Development
Libby, A. R. G.; Joy, D. A.; Elder, N. H.; Bulger, E. A.; Krakora, M. Z.; Gaylord, E. A.; Mendoza-Camacho, F.; Butts, J. C.; McDevitt, T. C.
10.1101/2020.03.05.979732 — developmental biology — Posted on 2020-12-16
1779 DOCK5 stabilises the leading edge in migrating cells to promote YAP/TAZ activation.
Pascual-Vargas, P. P.; Arias-Garcia, M.; Roumeliotis, T. I.; Chaudhary, J. S.; Bakal, C.
10.1101/2020.07.24.218313 — cell biology — Posted on 2020-12-16
1780 A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs
Nguyen, T.; Phan, K. L.; Kreitler, D. E.; Andrews, L. C.; Gabelli, S. B.; Kozakov, D.; Jakoncic, J.; Sweet, R. M.; Soares, A.; Bernstein, H. J.
10.1101/2020.12.14.422680 — molecular biology — Posted on 2020-12-16
1782 Network alignment and similarity reveal atlas-based topological differences in structural connectomes
Frigo, M.; Cruciani, E.; Coudert, D.; Deriche, R.; Natale, E.; Deslauriers-Gauthier, S.
10.1101/2020.12.16.422501 — neuroscience — Posted on 2020-12-16
1783 Critical role for astrocyte NAD+ glycohydrolase in myelin injury and regeneration
Langley, M. R.; Choi, C.-I.; Peclat, T. R.; Guo, Y.; Simon, W. L.; Yoon, H.; Kleppe, L.; Lucchinetti, C. F.; Chini, C. C.; Chini, E. N.; Scarisbrick, I. A.
10.1101/2020.06.10.143941 — neuroscience — Posted on 2020-12-16
1788 SUSD4 controls GLUA2 degradation, synaptic plasticity and motor learning
Gonzalez-Calvo, I.; Iyer, K.; Carquin, M.; Khayachi, A.; Giuliani, F. A.; Vincent, J.; Seveno, M.; Sigoillot, S. M.; Veleanu, M.; Tahraoui, S.; Albert, M.; Vigy, O.; Bosso-Lefevre, C.; Nadjar, Y.; Dumoulin, A.; Triller, A.; Bessereau, J.-L.; Rondi-Reig, L.; Isope, P.; Selimi, F.
10.1101/859587 — neuroscience — Posted on 2020-12-16
1789 The role of dopamine in reward-based motor adaptation, savings, and interference
Palidis, D. J.; McGregor, H. R.; Vo, A.; MacDonald, P. A.; Gribble, P. L.
10.1101/2020.11.19.390302 — neuroscience — Posted on 2020-12-16
1793 Sfaira accelerates data and model reuse in single cell genomics
Fischer, D. S.; Dony, L.; Koenig, M.; Moeed, A.; Zappia, L.; Tritschler, S.; Holmberg, O.; Aliee, H.; Theis, F. J.
10.1101/2020.12.16.419036 — bioinformatics — Posted on 2020-12-16
1794 HAYSTAC: A Bayesian framework for robust and rapid species identification in high-throughput sequencing data
Dimopoulos, E. A.; Carmagnini, A.; Velsko, I. M.; Warinner, C.; Larson, G.; Frantz, L. A. F.; Irving-Pease, E. K.
10.1101/2020.12.16.419085 — bioinformatics — Posted on 2020-12-16
1795 GUNC: Detection of Chimerism and Contamination in Prokaryotic Genomes
Orakov, A. N.; Fullam, A. N.; Coelho, L. P.; Khedkar, S.; Szklarczyk, D.; Mende, D. R.; Schmidt, T. S.; Bork, P.
10.1101/2020.12.16.422776 — bioinformatics — Posted on 2020-12-16
1796 EXPERIMENTAL INVESTIGATION OF PULSE STERILIZATION OF VIRAL INFECTION
Chumakov, V. I.; Ostryzhny, M.; Kharchenko, O.; Naumenko, K.; Zagorodnya, S.; Muraveinyk, V.; Tarasevich, A.
10.1101/2020.12.16.423002 — bioengineering — Posted on 2020-12-16
1798 Evidence for shared ancestry between Actinobacteria and Firmicutes bacteriophages
Koert, M.; Lopez-Perez, J.; Mattson, C.; Caruso, S. M.; Erill, I.
10.1101/842583 — genomics — Posted on 2020-12-16
1799 Linking the dynamics of chromatin occupancy and transcription with predictive models
Tran, T. Q.; MacAlpine, H.; Tripuraneni, V.; Mitra, S.; MacAlpine, D. M.; Hartemink, A. J.
10.1101/2020.06.28.176545 — genomics — Posted on 2020-12-16
1804 Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC/GEEC endocytic pathway
Prabhakara, C.; Godbole, R.; Sil, P.; Jahnavi, S.; van Zanten, T. S.; Sheth, D.; Subhash, N.; Chandra, A.; Nuthakki, V. K.; Puthiyapurayil, T. P.; Ahmed, R.; Najar, A. H.; Lingamallu, S. M.; Das, S.; Mahajan, B.; Vemula, P. K.; Bharate, S. B.; Singh, P. P.; Vishwakarma, R.; Guha, A.; Sundaramurthy, V.; Mayor, S.
10.1101/2020.12.16.422529 — cell biology — Posted on 2020-12-16
1805 Detection of long SARS-CoV-2 nucleocapsid sequences in peripheral blood monocytes collected soon after hospital admission
Pagano, N.; Laurent-Rolle, M.; Hsu, J. C.; Yale IMPACT Research Team, ; Vogels, C. B.; Grubaugh, N. D.; Manuelidis, L.
10.1101/2020.12.16.423113 — microbiology — Posted on 2020-12-16
1806 Disruption of Z-RNA-binding of ADAR1 induces Aicardi-Goutieres syndrome-like encephalopathy in mice
Nakahama, T.; Kato, Y.; Shibuya, T.; Kim, J. I.; Vongpipatana, T.; Todo, H.; Xing, Y.; Kawahara, Y.
10.1101/2020.12.16.422984 — immunology — Posted on 2020-12-16
1808 Astrocytes amplify cerebral blood flow elevation to sustained cortical activation in the awake mouse
Institoris, A.; Vandal, M.; Peringod, G.; Tran, C. H.; Yu, X.; Breiteneder, C.; Molina, L.; KHAKH, B. S.; Nguyen, M. D.; Thompson, R. J.; Gordon, G. R.
10.1101/2020.12.16.422785 — neuroscience — Posted on 2020-12-16
1809 ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells
Verma, P.; Zhou, Y.; Cao, Z.; Deraska, P.; Deb, M.; Arai, E.; Li, W.; Shao, Y.; Li, Y.; Puentes, L.; patankar, s.; Mach, R. H.; Faryabi, R. B.; Shi, J.; Greenberg, R. A.
10.1101/2020.12.16.422851 — cancer biology — Posted on 2020-12-16
1810 Molecular and functional basis of a novel Amazonian Dark Earth Esterase 1 (Ade1) with hysteresis behavior and quorum-quenching activity
Vinces, T. G. C.; Souza, A. S. d.; Carvalho, C.; Teixeira, R. D.; Bismara, B. A. P.; Vicente, E. J.; Pereira, J. O.; Souza, R. F. d.; Yonamine, M.; Marana, S. R.; Farah, C. S.; Guzzo, C. R.
10.1101/2020.12.16.421545 — biochemistry — Posted on 2020-12-16
1814 Combining an alarmin HMGN1 peptide with PD-L1 blockade facilitates stem-like CD8+ T cell expansion and results in robust antitumor effects
Chen, C.-Y.; Ueha, S.; Ishiwata, Y.; Shichino, S.; Yokochi, S.; Yang, D.; Oppenheim, J. J.; Ogiwara, H.; Deshimaru, S.; Kanno, Y.; Ogawa, T.; Shibayama, S.; Matsushima, K.
10.1101/2020.12.15.422990 — immunology — Posted on 2020-12-16
1815 Under-oil autonomously regulated oxygen microenvironments for cell culture
Li, C.; Humayun, M.; Park, K. Y.; Connors, B.; Feng, J.; Li, J.; Feng, Y.; Clark, R. L.; Hefti, H.; Schrope, J.; Venturelli, O. S.; Beebe, D. J.
10.1101/2020.12.16.423117 — bioengineering — Posted on 2020-12-16
1818 A wolf in another wolf's clothing. Post-genomic regulation dictates venom profiles of medically-important cryptic kraits in India
Sunagar, K.; Khochare, S.; Senji Laxme, R. R.; Attarde, S.; Dam, P.; Suranse, V.; Khaire, A.; Martin, G.; Captain, A.
10.1101/2020.12.15.422536 — evolutionary biology — Posted on 2020-12-16
1823 Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair
Wu, W.; Hill, S.; Nathan, W.; Paiano, J.; Shinoda, K.; Colon-Mercado, J.; Callen, E.; De Pace, R.; Wang, D.; Shih, H.-Y.; Coon, S.; Parsadanian, M.; Hanzlikova, H.; Mchugh, P.; Canela, A.; Caldecott, K.; Ward, M. E.; Nussenzweig, A.
10.1101/2020.12.16.423085 — neuroscience — Posted on 2020-12-16
1824 Paracrine interactions between epithelial cells promote colon cancer growth
Jacquemin, G.; Wurmser, A.; Huyghe, M.; Sun, W.; Qasrawi, F.; Perkins, M.; Dingli, F.; Arras, G.; Loew, D.; Fre, S.
10.1101/2020.12.16.423051 — cancer biology — Posted on 2020-12-16
1825 HTSlib - C library for reading/writing high-throughput sequencing data
Bonfield, J. K.; Marshall, J.; Danecek, P.; Li, H.; Ohan, V.; Whitwham, A.; Keane, T.; Davies, R. M.
10.1101/2020.12.16.423064 — bioinformatics — Posted on 2020-12-16
1832 Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a Notch-dependent manner
Sampaolesi, M.; Breuls, N.; Giarratana, N.; Yedigaryan, L.; Carai, P.; Heymans, S.; Ranga, A.; Deroose, C.
10.1101/2020.12.16.423053 — cell biology — Posted on 2020-12-16
1833 Transcription and replication organize cohesin-dependent chromosome loops
Jeppsson, K.; Sakata, T.; Nakato, R.; Milanova, S.; Shirahige, K.; Bjoerkegren, C.
10.1101/2020.12.16.423068 — molecular biology — Posted on 2020-12-16
1835 Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress, and invasion
Schlott, A. C.; Knuepfer, E.; Green, J. L.; Hobson, P.; Borg, A. J.; Morales-Sanfrutos, J.; Perrin, A. J.; Snijders, A. P.; Tate, E. W.; Holder, A. A.
10.1101/2020.12.16.423054 — microbiology — Posted on 2020-12-16
1837 Non-deletional CD8+ T cell self-tolerance permits responsiveness but limits tissue damage
Truckenbrod, E. N.; Burrack, K. S.; Knutson, T. P.; Borges da Silva, H.; Block, K. E.; Stagliano, K. R.; Hurwitz, A. A.; Fulton, R. B.; Renkema, K.; Jameson, S. C.
10.1101/2020.12.16.423036 — immunology — Posted on 2020-12-16
1838 An unconventional conductance is required for pacemaking of nigral dopamine neurons
Jehasse, K.; Massotte, L.; Hartmann, S.; Vitello, R.; Ringlet, S.; Vitello, M.; Chua, H. C.; Pless, S.; Engel, D.; Liegeois, J.-F.; Lakaye, B.; Roeper, J.; Seutin, V.
10.1101/2020.12.16.423073 — neuroscience — Posted on 2020-12-16
1839 Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation.
Sanjuan-Ruiz, I.; Govea-Perez, N.; McAlonis-Downes, M.; Dieterle, S.; Megat, S.; Dirrig-Grosch, S.; Picchiarelli, G.; Piol, D.; Zhu, Q.; Myers, B. D.; Lee, C.-Z.; Cleveland, D. W.; Lagier-Tourenne, C.; Da Cruz, S.; Dupuis, L.
10.1101/2020.12.16.423060 — neuroscience — Posted on 2020-12-16
1844 A midbrain - thalamus - cortex circuit reorganizes cortical dynamics to initiate planned movement
Inagaki, H. K.; Chen, S.; Ridder, M. C.; Sah, P.; Li, N.; Yang, Z.; Hasanbegovic, H.; Gao, Z.; Gerfen, C. R.; Svoboda, K.
10.1101/2020.12.16.423127 — neuroscience — Posted on 2020-12-16
1845 Abnormal Cannabidiol protects pancreatic beta cells in mouse models of experimental Type 1 diabetes
Gonzalez-Mariscal, I.; Pozo-Morales, M.; Romero-Zerbo, S. Y.; Espinosa-Jimenez, V.; Escamilla-Sanchez, A.; Sanchez-Salido, L.; Cobo-Vuilleumier, N.; Gauthier, B. R.; Bermudez-Silva, F. J.
10.1101/2020.12.16.423103 — pharmacology and toxicology — Posted on 2020-12-16
1847 Comparative genomics of peroxisome biogenesis proteins: making sense of the PEX mess
Jansen, R. L. M.; Santana Molina, C.; van den Noort, M.; Devos, D.; van der Klei, I. J.
10.1101/2020.12.16.423121 — bioinformatics — Posted on 2020-12-16
1848 TranSuite: a software suite for accurate translation and characterization of transcripts
Entizne, J. C.; Guo, W.; Calixto, C. P. G.; Spensley, M.; Tzioutziou, N. A.; Zhang, R.; Brown, J. W.
10.1101/2020.12.15.422989 — bioinformatics — Posted on 2020-12-16
1849 DoChaP: The Domain Change Presenter
Gal-Oz, S. T.; Haiat, N.; Eliyahu, D.; Shani, G.; Shay, T.
10.1101/2020.12.16.423045 — bioinformatics — Posted on 2020-12-16
1851 Continental-scale genomic analysis suggests shared post-admixture adaptation in Americas
Ongaro, L.; Mondal, M.; Flores, R.; Marnetto, D.; Molinaro, L.; Alarcon-Riquelme, M. E.; Moreno-Estrada, A.; Mabunda, N.; Ventura, M.; Tambets, K.; Hellenthal, G.; Capelli, C.; Kivisild, T.; Metspalu, M.; Pagani, L.; Montinaro, F.
10.1101/2020.12.16.423075 — genomics — Posted on 2020-12-16
1852 De novo assembly of 64 haplotype-resolved human genomes of diverse ancestry and integrated analysis of structural variation
Ebert, P.; Audano, P. A.; Zhu, Q.; Rodriguez-Martin, B.; Porubsky, D.; Bonder, M. J.; Sulovari, A.; Ebler, J.; Zhou, W.; Serra Mari, R.; Yilmaz, F.; Zhao, X.; Hsieh, P.; Lee, J.; Kumar, S.; Lin, J.; Rausch, T.; Chen, Y.; Ren, J.; Santamarina, M.; Hoeps, W.; Ashraf, H.; Chuang, N. T.; Yang, X.; Munson, K. M.; Lewis, A. P.; Fairley, S.; Tallon, L. J.; Clarke, W. E.; Basile, A. O.; Byrska-Bishop, M.; Corvelo, A.; Chaisson, M. J. P.; Chen, J.; Li, C.; Brand, H.; Wenger, A. M.; Ghareghani, M.; Harvey, W.; Raeder, B.; Hasenfeld, P.; Regier, A.; Abel, H.; Hall, I.; Flicek, P.; Stegle, O.; Gerstein, M
10.1101/2020.12.16.423102 — genetics — Posted on 2020-12-16
1855 A dynamic and hierarchical spatial occupancy model for interacting species
Kleiven, E. F.; Barraquand, F.; Gimenez, O.; Henden, J.-A.; Ims, R. A.; Soininen, E. M.; Yoccoz, N. G.
10.1101/2020.12.16.423067 — ecology — Posted on 2020-12-16
1857 Phospho-RNA sequencing with CircAID-p-seq
Del Piano, A.; Barbieri, R.; Schmid, M.; Brocchieri, L.; Tornaletti, S.; Firrito, C.; Minati, L.; Bernabo, P.; Signoria, I.; Lauria, F.; Gillingwater, T. H.; Viero, G.; Clamer, M.
10.1101/2020.12.16.423093 — molecular biology — Posted on 2020-12-16
1860 Methane-derived carbon flow through host-virus trophic networks in soil
Lee, S.; Sieradzki, E. T.; Nicolas, A. M.; Firestone, M. K.; Hazard, C.; Nicol, G. W.
10.1101/2020.12.16.423115 — microbiology — Posted on 2020-12-16
1861 Oncolytic virus treatment differentially affects the CD56dim and CD56bright NK cell subsets in vivo and regulates a spectrum of human NK cell activity
Wantoch, M.; Wilson, E. B.; Droop, A. P.; Phillips, S. L.; Coffey, M.; El-Sherbiny, Y. M.; Holmes, T. D.; Melcher, A. A.; Wetherill, L. F.; Cook, G. P.
10.1101/2020.12.16.423062 — immunology — Posted on 2020-12-16
1867 Mutation of the nuclear pore complex component, aladin1, disrupts asymmetric cell division in Zea mays (maize)
Best, N. B.; Addo-Quaye, C.; Kim, B.-S.; Weil, C.; Schulz, B.; Johal, G. S.; Dilkes, B. P.
10.1101/2020.12.16.423105 — genetics — Posted on 2020-12-16
1869 A versatile automated high-throughput drug screening platform for zebrafish embryos
Lubin, A.; Otterstrom, J.; Hoade, Y.; Bjedov, I.; Stead, E.; Whelan, M.; Gestri, G.; Paran, Y.; Payne, E.
10.1101/2020.12.16.423108 — cell biology — Posted on 2020-12-16
1870 Mechanism through which retrocyclin targets flavivirus multiplication
Jia, X.; Guo, J.; yuan, W.; Sun, L.; Liu, Y.; Zhou, M.; Xiao, G.; Lu, W.; Garzino-Demo, A.; Wang, W.
10.1101/2020.12.15.422996 — microbiology — Posted on 2020-12-16
1873 A standardized behavioral event equally impacts the activity of cortical visual areas and layers
Ramadan, M.; Lee, E. K.; Caldejon, S.; Kato, I.; Roll, K.; Griffin, F.; Nguyen, T.; Larkin, J.; Rhoads, P.; Mace, K.; Kriedberg, A.; Howard, R.; Berbesque, N.; Lecoq, J.
10.1101/2020.12.15.422967 — neuroscience — Posted on 2020-12-16
1874 Oxicam-type NSAIDs enhance Agrobacterium-mediated transformation in plants
Choi, S.-w.; Kumaishi, K.; Motohashi, R.; Enoki, H.; Chacuttayapong, W.; Takamizo, T.; Saika, H.; Endo, M.; Yamada, T.; Hirose, A.; Koizuka, N.; Kimura, S.; Kawakatsu, Y.; Koga, H.; Ito, E.; Shirasu, K.; Ichihashi, Y.
10.1101/2020.12.15.422982 — plant biology — Posted on 2020-12-16
1876 uPTI: uniaxial permittivity tensor imaging of intrinsic density and anisotropy
Yeh, L.-H.; Ivanov, I. E.; Chhun, B. B.; Guo, S.-M.; Hashemi, E.; Byrum, J. R.; Perez-Bermejo, J. A.; Wang, H.; Yu, Y.; Kazansky, P. G.; Conklin, B. R.; Han, M. H.; Mehta, S. B.
10.1101/2020.12.15.422951 — biophysics — Posted on 2020-12-16
1877 Open-source mapping and variant calling for large-scale NGS data from original base-quality scores
Krasheninina, O.; Hwang, Y.-C.; Bai, X.; Zalcman, A.; Maxwell, E.; Reid, J. G.; Salerno, W. J.
10.1101/2020.12.15.356360 — bioinformatics — Posted on 2020-12-16
1878 Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
Liu, P.; Liang, S.; Zheng, C.; Mintzer, E.; Zhao, Y. G.; Ponnienselvan, K.; Mir, A.; Sontheimer, E. J.; Gao, G.; Flotte, T. R.; Wolfe, S.; Xue, W.
10.1101/2020.12.15.422970 — bioengineering — Posted on 2020-12-16
1881 Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen
Kuzikov, M.; Costanzi, E.; Reinshagen, J.; Esposito, F.; Vangeel, L.; Wolf, M.; Ellinger, B.; Claussen, C.; Geisslinger, G.; Corona, A.; Iaconis, D.; Talarico, C.; Manelfi, C.; Cannalire, R.; Rossetti, G.; Gossen, J.; Albani, S.; Musiani, F.; Herzog, K.; Ye, Y.; Giabbai, B.; Demitri, N.; Jochmans, D.; De Jonghe, S.; Rymenants, J.; Summa, V.; Tramontano, E.; Beccari, A. R.; Leyssen, P.; Storici, P.; Neyts, J.; Gribbon, P.; Zaliani, A.
10.1101/2020.12.16.422677 — molecular biology — Posted on 2020-12-16
1883 Deep learning-based classification of resting-state fMRI independent-component analysis
Nozais, V.; Boutinaud, P.; Verrecchia, V.; Gueye, M.-F.; Herve, P. Y.; Tzourio, C.; Mazoyer, B.; Joliot, M.
10.1101/2020.07.02.183772 — neuroscience — Posted on 2020-12-16
1891 Uneven protection of persistent giant kelp forest in the Northeast Pacific Ocean
Arafeh-Dalmau, N.; Cavanaugh, K.; Possingham, H.; Munguia-Vega, A.; Montano-Moctezuma, G.; Bell, T.; Cavanaugh, K.; Micheli, F.
10.1101/2020.12.15.422778 — ecology — Posted on 2020-12-16
1895 CERMEP-IDB-MRXFDG: A database of 37 normal adult human brain FDG PET, T1 and FLAIR MRI, and CT images available for research
Merida, I.; Jung, J.; Bouvard, S.; Le Bars, D.; Lancelot, S.; Lavenne, F.; Bouillot, C.; Redoute, J.; Hammers, A.; Costes, N.
10.1101/2020.12.15.422636 — neuroscience — Posted on 2020-12-16
1897 Integration of Cell Growth and Asymmetric Division During Lateral Root Initiation In Arabidopsis thaliana
Schuetz, L.; Louveaux, M.; Vilches Barro, A.; Bouziri, S.; Cerrone, L.; Wolny, A.; Kreshuk, A.; Hamprecht, F. A.; Maizel, A.
10.1101/2020.12.15.422941 — plant biology — Posted on 2020-12-16
1900 Structural and functional insights into the mechanism of action of plant boron transporters
Saouros, S.; Mohan, T. C.; Cecchetti, C.; Lehmann, S.; Barritt, J. D.; Scull, N. J.; Simpson, P.; Alguel, Y.; Cameron, A. D.; Jones, A. M. E.; Byrne, B.
10.1101/2020.12.15.422910 — plant biology — Posted on 2020-12-16
1901 A neural crest stem cell-like state drives nongenetic resistance to targeted therapy in melanoma
Marin-Bejar, O.; Rogiers, A.; Dewaele, M.; Femel, J.; Karras, P.; Pozniak, J.; Bervoets, G.; Van Raemdonck, N.; Pedri, D.; Swings, T.; Demeulemeester, J.; Vander Borght, S.; Bosisio, F.; van den Oord, J. J.; Vanden Bempt, I.; Lambrechts, D.; Voet, T.; Bechter, O.; Rizos, H.; Levesque, M.; Leucci, E.; Lund, A. W.; Rambow, F.; Marine, J.-C.
10.1101/2020.12.15.422929 — cancer biology — Posted on 2020-12-16
1904 A low-autofluorescence, transparent resin for multiphoton 3D printing
Flamourakis, G.; Kordas, A.; Barmparis, G.; Ranella, A.; Farsari, M.
10.1101/2020.12.15.422922 — bioengineering — Posted on 2020-12-16
1905 Robot-Assisted SpiderMass for in vivo Real-Time Topography Mass Spectrometry Imaging
Ogrinc, N.; Kruszewski, A.; Chaillou, P.; Saudemont, P.; Lagadec, C.; Salzet, M.; Duriez, C.; Fournier, I.
10.1101/2020.12.15.422889 — biochemistry — Posted on 2020-12-16
1906 The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
Gentile, A.; Bensimon-Brito, A. Y. R.; Priya, R.; Maischein, H.-M.; Piesker, J.; Guenther, S.; Gunawan, F.; Stainier, D.
10.1101/2020.12.15.422833 — developmental biology — Posted on 2020-12-16
1908 The GPIbα intracellular tail - role in transducing VWF- and Collagen/GPVI-mediated signaling
Constantinescu-Bercu, A.; Wang, Y. A.; Woollard, K.; Mangin, P.; Vanhoorelbeke, K.; Crawley, J. T.; Salles-Crawley, I. I.
10.1101/2020.12.16.423021 — cell biology — Posted on 2020-12-16
1910 Molecular topography of an entire nervous system
Taylor, S. R.; Santpere, G.; Weinreb, A.; Barrett, A.; Reilly, M. B.; Xu, C.; Varol, E.; Oikonomou, P.; Glenwinkel, L.; McWhirter, R.; Poff, A.; Basavaraju, M.; Rafi, I.; Yemini, E.; Cook, S. J.; Abrams, A.; Vidal, B.; Cros, C.; Tavazoie, S.; Sestan, N.; Hammarlund, M.; Hobert, O.; Miller, D. M.
10.1101/2020.12.15.422897 — neuroscience — Posted on 2020-12-16
1912 A Systematic and Consistent Assay for High-throughput Characterization of Stalk Quality in Sugarcane by Near-infrared Spectroscopy
Wang, M.; Shen, Y.; Li, X.; Adnan, M.; Mao, L.; Lu, P.; Hu, Q.; Jiang, F.; Khan, M. T.; Deng, Z.; Huang, J.; Zhang, M.
10.1101/2020.12.14.409383 — plant biology — Posted on 2020-12-16
1915 A Guide to Pre-Processing High-Throughput Animal Tracking Data
Gupte, P. R.; Beardsworth, C. E.; Spiegel, O.; Lourie, E.; Toledo, S.; Nathan, R.; Bijleveld, A. I.
10.1101/2020.12.15.422876 — ecology — Posted on 2020-12-16
1917 DDI2 protease activity controls embryonic development and inflammation via TCF11/NRF1
Siva, M.; Haberecht-Müller, S.; Prochazkova, M.; Prochazka, J.; Sedlak, F.; Chawengsaksophak, K.; Kasparek, P.; Sedlacek, R.; Konvalinka, J.; Krüger, E.; Grantz Saskova, K.
10.1101/2020.12.16.423023 — cell biology — Posted on 2020-12-16
1918 Characterization of highly proliferative decidual precursor cells during the window of implantation in human endometrium
Diniz-da-Costa, M.; Kong, C.-S.; Fishwick, K. J.; Rawlings, T.; Brighton, P. J.; Hawkes, A.; Odendaal, J.; Quenby, S.; Ott, S.; Lucas, E. S.; Vrljicak, P. S.; Brosens, J. J.
10.1101/2020.12.16.423007 — cell biology — Posted on 2020-12-16
1919 SUMO-specific protease 2 (SENP2) suppresses browning of white adipose tissue through C/EBPβ modulation
Lee, J. S.; Chae, S.; Nan, J.; Koo, Y. D.; Lee, S.-A.; Park, Y. J.; Hwang, D.; Han, W.; Kim, Y.-B.; Chung, S. S.; Park, K. S.
10.1101/2020.12.16.422969 — cell biology — Posted on 2020-12-16
1920 Sestrins regulate age-induced deterioration of muscle stem cell homeostasis
Yang, B. A.; Castor-Macias, J. A.; Fraczek, P. M.; Brown, L. A.; Kim, M.; Brooks, S. V.; Lee, J. H.; Aguilar, C. A.
10.1101/2020.12.15.422905 — cell biology — Posted on 2020-12-16
1921 Nucleolar TFIIE plays a role in ribosomal biogenesis and performance
Phan, T.; Maity, P.; Ludwig, C.; Streit, L.; Michaelis, J.; Scharffetter-Kochanek, K.; Iben, S.
10.1101/2020.12.16.423046 — cell biology — Posted on 2020-12-16
1923 InSegtCone: Interactive Segmentation of crystalline Cones in compound eyes
Tichit, P. B. T.; Zhou, T.; Kjer, H. M.; Andersen Dahl, V.; Bjorholm Dahl, A.; Baird, E.
10.1101/2020.12.15.422850 — zoology — Posted on 2020-12-16
1926 Do Motoneurons Slow With Aging? A Systematic Review And Meta-Analysis With Meta-Regression
Orssatto, L. B. R.; Borg, D.; Pendrith, L.; Shield, A. J.; Blazevich, A. J.; Trajano, G. S.
10.1101/2020.12.15.422812 — physiology — Posted on 2020-12-16
1927 COPLA, a taxonomic classifier of plasmids
Redondo-Salvo, S.; Bartomeus, R.; Vielva, L.; Tagg, K. A.; Webb, H. E.; Fernandez-Lopez, R.; de la Cruz, F.
10.1101/2020.12.15.422809 — bioinformatics — Posted on 2020-12-16
1930 Predicting compound activity from phenotypic profiles and chemical structures
Becker, T.; Yang, K.; Caicedo, J. C.; Wagner, B. K.; Dancik, V. C.; Clemons, P. C.; Singh, S.; Carpenter, A. E.
10.1101/2020.12.15.422887 — bioinformatics — Posted on 2020-12-16
1932 Quantitative Genetic Scoring, or how to put a number on an arbitrary genetic region
Schoenmacker, G. H.; Vlaming, P.; Pallesen, J.; Pikulina, M. Y.; Ghamarian, A. H.; Demontis, D. H.; Borglum, A.; Galesloot, T. E.; Poelmans, G.; Franke, B.; Claassen, T.; Heskes, T.; Buitelaar, J.; Arias Vasquez, A.
10.1101/2020.12.15.422886 — bioinformatics — Posted on 2020-12-16
1938 First-in-class matrix anti-assembly peptide prevents staphylococcal biofilm in vitro and in vivo
GOMES VON BOROWSKI, R.; CHAT, S.; SCHNEIDER, R.; Nonin-Lecomte, S.; BOUAZIZ, S.; GIUDICE, E.; RIGON ZIMMER, A.; Baggio Gnoatto, S. C.; MACEDO, A. J.; GILLET, R.
10.1101/2020.04.03.022020 — microbiology — Posted on 2020-12-16
1939 The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro
Yaron, T. M.; Heaton, B. E.; Levy, T. M.; Johnson, J. L.; Jordan, T. X.; Cohen, B. M.; Kerelsky, A.; Lin, T.-Y.; Liberatore, K. M.; Bulaon, D. K.; Kastenhuber, E. R.; Mercadante, M. N.; Shobana-Ganesh, K.; He, L.; Schwartz, R. E.; Chen, S.; Weinstein, H.; Elemento, O.; Piskounova, E.; Nilsson-Payant, B. E.; Lee, G.; Trimarco, J. D.; Burke, K. N.; Hamele, C. E.; Chaparian, R. R.; Harding, A. T.; Tata, A.; Zhu, X.; Tata, P. R.; Smith, C. M.; Possemato, A. P.; Tkachev, S. L.; Hornbeck, P. V.; Beausoleil, S. A.; Anand, S. K.; Aguet, F.; Getz, G.; Davidson, A. D.; Heesom, K.; Kavanagh-Williamson, M
10.1101/2020.08.14.251207 — microbiology — Posted on 2020-12-16
1940 Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response
Gangaev, A.; Rozeman, E. A.; Rohaan, M. W.; Philips, D.; Patiwael, S.; van den Berg, J. H.; Ribas, A.; Schadendorf, D.; Schilling, B.; Shumacher, T.; Blank, C.; Haanen, J. B. A. G.; Kvistborg, P.
10.1101/2020.12.15.422827 — immunology — Posted on 2020-12-16
1942 Resting-state functional connectivity and psychopathology in Klinefelter syndrome (47, XXY)
Whitman, E. T.; Liu, S.; Torres, E.; Warling, A.; Wilson, K.; Nadig, A.; McDermott, C.; Clasen, L. S.; Blumenthal, J. D.; Lalonde, F. M.; Gotts, S. J.; Martin, A.; Raznahan, A.
10.1101/2020.12.15.422868 — neuroscience — Posted on 2020-12-16
1944 The historic range and drivers of decline of the Tapanuli orangutan
Meijaard, E.; Ni'matullah, S.; Dennis, R.; Sherman, J.; Onrizal, O.; Wich, S. A.
10.1101/2020.08.11.246058 — zoology — Posted on 2020-12-16
1948 Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane
Sabnis, A.; Hagart, K. L. H.; Klockner, A.; Becce, M.; Evans, L. E.; Furniss, R. C. D.; Mavridou, D. A. I.; Murphy, R.; Stevens, M. M.; Davies, J. C.; Larrouy-Maumus, G.; Clarke, T. B.; Edwards, A. M.
10.1101/479618 — microbiology — Posted on 2020-12-16
1949 Plasma glutathione status as indicator of pre-analytical centrifugation delay
Tamara, T.; Bordag, N.; Zuegner, E.; Al-Baghdadi, A.; Schinagl, M.; Birner-Gruenberger, R.; Schittmayer, M.
10.1101/2020.12.09.417386 — pathology — Posted on 2020-12-16
1951 Co-option of a seed-like proteome by oil-rich tubers
Niemeyer, P. W.; Schmitt, K.; Valerius, O.; Braus, G. H.; deVries, J.; Carlsson, A. S.; Hofvander, P.; Ischebeck, T.
10.1101/2020.12.15.422834 — evolutionary biology — Posted on 2020-12-16
1952 Shifts from pulled to pushed range expansions caused by reduction of landscape connectivity
Dahirel, M.; Bertin, A.; Haond, M.; Blin, A.; Lombaert, E.; Calcagno, V.; Fellous, S.; Mailleret, L.; Malausa, T.; Vercken, E.
10.1101/2020.05.13.092775 — ecology — Posted on 2020-12-16
1953 Social groups with diverse personalities mitigate physiological stress in a songbird
Vagasi, C. I.; Fulop, A.; Osvath, G.; Pap, P. L.; Penzes, J.; Benko, Z.; Lendvai, A. Z.; Barta, Z.
10.1101/2020.04.15.043471 — ecology — Posted on 2020-12-16
1956 Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys
Srivastava, S. P.; Li, J.; Takagaki, Y.; Kitada, M.; Goodwin, J. E.; Kanasaki, K.; Koya, D.
10.1101/2020.12.15.422824 — cell biology — Posted on 2020-12-16
1957 DRAM1 requires PI(3,5)P2 generation by PIKfyve to deliver vesicles and their cargo to endolysosomes
van der Vaart, M.; Banducci-Karp, A.; Forn-Cuni, G.; Witt, P. M. M.; Willemse, J. J.; Sanchez, S. M.; Hosseini, R.; Meijer, A. H.
10.1101/2020.12.15.422832 — molecular biology — Posted on 2020-12-16
1958 Queuine is a nutritional regulator of Entamoeba histolytica response to oxidative stress and a virulence attenuator
Nagaraja, S.; Cai, M. W.; Sun, J.; Varet, H.; Sarid, L.; Shaulov, Y.; Trebicz-Geffen, M.; Mazumdar, M.; Legendre, R.; Coppee, J.-Y.; Begley, T.; Dedon, P. C.; Gourinath, S.; Guillen, N.; Saito-Nakano, Y.; Shimokawa, C.; Hisaeda, H.; Ankri, S.
10.1101/2020.04.30.070276 — microbiology — Posted on 2020-12-16
1959 Putative Pseudolysogeny-Dependent Phage Gene Implicated in the Superinfection Resistance of Cutibacterium acnes
Wottrich, S.; Mendonca, S.; Safarpour, C.; Nguyen, C.; Marinelli, L. J.; Modlin, R. L.; Moberg Parker, J.
10.1101/2020.12.15.422974 — microbiology — Posted on 2020-12-16
1960 Physiological and pathological changes in the enteric nervous system of rotenone-exposed mice as potential early biomarkers for Parkinson's disease
Schaffernicht, G.; Shang, Q.; Stievenard, A.; Bötzel, K.; Dening, Y.; Kempe, R.; Toussaint, M.; Gündel, D.; Kranz, M.; Reichmann, H.; Vanbesien-Mailliot, C.; Brust, P.; Dieterich, M.; Funk, R. H. W.; Ravens, U.; Pan-Montojo, F. J.
10.1101/2020.12.11.421164 — neuroscience — Posted on 2020-12-16
1964 Single-Molecule Imaging and Microfluidic Platform Reveal Molecular Mechanisms of Leukemic Cell Rolling
Al Alwan, B.; AbuZineh, K.; Nozue, S.; Rakhmatulina, A.; Aldehaiman, M.; Al-Amoodi, A. S.; Serag, M. F.; Aleisa, F. A.; Merzaban, J. S.; Habuchi, S.
10.1101/2020.04.29.069617 — biophysics — Posted on 2020-12-16
1966 Longest Order Conserved Exemplar Subsequences
Zhang, S.; Pu, L.; Yang, R.; Wang, L.; Zhu, D.; Jiang, H.
10.1101/2020.12.15.422841 — bioinformatics — Posted on 2020-12-15
1967 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, L. D.; Li, W.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2020-12-15
1968 Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments
Wang, J.; Zhao, Q.; Bowden, J.; Hemani, G.; Smith, G. D.; Small, D.; Zhang, N. R.
10.1101/2020.05.06.077982 — genetics — Posted on 2020-12-15
1969 Whole-organism eQTL mapping at cellular resolution with single-cell sequencing
Ben-David, E.; Boocock, J.; Guo, L.; Zdraljevic, S.; Bloom, J. S.; Kruglyak, L.
10.1101/2020.08.23.263798 — genetics — Posted on 2020-12-15
1970 GAI MoRFs Regulate Cleft and Channel Binding Pathways for Gibberellin in GID1A
Patterson, J.; David, C. C.; Wood, M.; Sun, X.; Jacobs, D. J.; Rikkerink, E. H. A.
10.1101/2020.12.15.422840 — molecular biology — Posted on 2020-12-15
1971 Increased connectivity among sensory and motor regions during visual and audiovisual speech perception
Peelle, J. E.; Spehar, B.; Jones, M. S.; McConkey, S.; Myerson, J.; Hale, S.; Sommers, M. S.; Tye-Murray, N.
10.1101/2020.12.15.422726 — neuroscience — Posted on 2020-12-15
1973 The role of anatomical connection strength for interareal communication in macaque cortex
Vezoli, J.; Vinck, M.; Bosman, C. A.; Bastos, A. M.; Lewis, C. M.; Kennedy, H.; Fries, P.
10.1101/2020.12.15.422902 — neuroscience — Posted on 2020-12-15
1978 Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
Rives, A.; Meier, J.; Sercu, T.; Goyal, S.; Lin, Z.; Liu, J.; Guo, D.; Ott, M.; Zitnick, C. L.; Ma, J.; Fergus, R.
10.1101/622803 — synthetic biology — Posted on 2020-12-15
1979 Optimized gene expression from bacterial chromosome by high-throughput integration and screening
Saleski, T. E.; Chung, M. T.; Carruthers, D. N.; Khasbaatar, A.; Kurabayashi, K.; Lin, X.
10.1101/2020.07.29.226290 — synthetic biology — Posted on 2020-12-15
1981 Regulation of the plastochron by three MANY-NODED DWARF genes in barley
Hibara, K.-i.; Miya, M.; Benvenuto, S. A.; Hibara-Matsuo, N.; Mimura, M.; Yoshikawa, T.; Suzuki, M.; Kusaba, M.; Taketa, S.; Itoh, J.
10.1101/2020.12.15.422847 — plant biology — Posted on 2020-12-15
1990 SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2
Hernandez-Garcia, A.; Kim, S.; Li, Y.; Kim, B. J.; Zaveri, H. P.; Jordan, V. K.; Ljungberg, M. C.; Chen, R.; Lanz, R. B.; Scott, D. A.
10.1101/2020.12.04.412288 — developmental biology — Posted on 2020-12-15
1992 Alpha-tubulin acetylation in Trypanosoma cruzi: a dynamic instability of microtubules is required for replication and cell cycle progression
Alonso, V. L.; Carloni, M. E.; Silva Goncalves, C.; Martinez Peralta, G.; Chesta, M. E.; Pezza, A.; Tavernelli, L. E.; Machado Motta, M. C.; Serra, E. C.
10.1101/2020.12.15.422917 — cell biology — Posted on 2020-12-15
1994 Microbiome and Metabolome driven differentiation of TGF-beta producing Tregs leads to Senescence and HIV latency
Ghneim, K.; Sharma, A. A.; Ribeiro, S. P.; Fourati, S.; Ahlers, J.; Kulpa, D.; Xu, X.; Brehm, J.; Talla, A.; Arumugam, S.; Darko, S.; Rodriguez, B.; Shive, C.; Cristescu, R.; Loboda, A.; Balderas, R.; Wang, I.-m.; Hunt, P.; Lamarre, D.; Douek, D.; Hazuda, D.; Lederman, M.; Deeks, S.; Sekaly, R.-P.
10.1101/2020.12.15.422949 — immunology — Posted on 2020-12-15
1996 Persistent Inward Currents Increase With The Level Of Voluntary Drive In Plantar Flexor Low-Threshold Motor Units
Orssatto, L. B. R.; Mackay, K.; Shield, A. J.; Sakugawa, R. L.; Blazevich, A. J.; Trajano, G. S.
10.1101/2020.12.11.420570 — neuroscience — Posted on 2020-12-15
1998 Physiological and pathological changes in the enteric nervous system of rotenone-exposed mice as potential early biomarkers for Parkinson's disease
Schaffernicht, G.; Shang, Q.; Stievenard, A.; Bötzel, K.; Dening, Y.; Kempe, R.; Toussaint, M.; Gündel, D.; Kranz, M.; Reichmann, H.; Vanbesien-Mailliot, C.; Brust, P.; Dieterich, M.; Funk, R. H. W.; Ravens, U.; Pan-Montojo, F. J.
10.1101/2020.12.11.421164 — neuroscience — Posted on 2020-12-15
2001 Information transfer and recovery for the sense of touch
Huang, C.; Englitz, B.; Reznik, A.; Zeldenrust, F.; Celikel, T.
10.1101/2020.12.08.415729 — neuroscience — Posted on 2020-12-15
2007 Conserved virulence-linked metabolic reprogramming in Clostridioides difficile identified through genome-scale metabolic network analysis
Jenior, M. L.; Leslie, J. L.; Powers, D. A.; Garrett, E. M.; Walker, K. A.; Dickenson, M. E.; Petri, W. A.; Tamayo, R.; Papin, J. A.
10.1101/2020.11.09.373480 — bioengineering — Posted on 2020-12-15
2008 Efficient Inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc
Wang, S.-S.; del Solar, V.; Yu, X.; Antonopoulos, A.; Friedman, A. E.; Agarwal, K.; Garg, M.; Ahmed, S. M.; Addhya, A.; Nasirikenari, M.; Lau, J. T.; Dell, A.; Haslam, S. M.; Sampathkumar, S.-G.; Neelamegham, S.
10.1101/2020.12.13.422539 — biochemistry — Posted on 2020-12-15
2011 Whole Genome Sequencing-based Characterization of Human Genome Variation and Mutation Burden in Botswana
Thami, P. K.; Choga, W. T.; Mulisa, D. D.; Dandara, C.; Shevchenko, A. K.; Leteane, M. M.; Novitsky, V.; O'Brien, S. J.; Essex, M.; Gaseitsiwe, S.; Chimusa, E. R.
10.1101/2020.12.15.422821 — genomics — Posted on 2020-12-15
2012 A CRISPR endonuclease gene drive reveals two distinct mechanisms of inheritance bias
Verkuijl, S. A. N.; Gonzalez, E.; Ang, J. X. D.; Li, M.; Kandul, N. P.; Anderson, M.; Akbari, O. S.; Bonsall, M.; Alphey, L.
10.1101/2020.12.15.421271 — genetics — Posted on 2020-12-15
2015 Nutrition or nature: disentangling the complex forces shaping prokaryote pan-genomes
Garza, D. R.; von Meijenfeldt, F. A. B.; van Dijk, B.; Boleij, A.; Huynen, M.; Dutilh, B. E.
10.1101/2020.12.14.422685 — evolutionary biology — Posted on 2020-12-15
2019 RORα enforces stability of the T-helper-17 cell effector program
Lee, J.-Y.; Hall, J. A.; Pokrovskii, M.; Kroehling, L.; Wu, L.; Littman, D. R.
10.1101/2020.12.15.422921 — immunology — Posted on 2020-12-15
2020 CRISPR knockdown of GABAA alpha3 subunits on thalamic reticular neurons enhances deep sleep
Uygun, D. S.; Yang, C.; Tilli, E. R.; Katsuki, F.; McKenna, J. T.; McNally, J. M.; Brown, R. E.; Basheer, R.
10.1101/2020.12.15.422912 — neuroscience — Posted on 2020-12-15
2021 Ageing and MPTP- sensitivity depend on molecular and ultrastructural signatures of astroglia and microglia in mice nigra
Abhilash, P.; Bharti, U.; Rashmi, S.; Raju, T. R.; Kutty, B. M.; Chandrashekar Sagar, B.; Alladi, P. A.
10.1101/2020.12.15.422212 — neuroscience — Posted on 2020-12-15
2022 Heterogeneous relationships between white matter and behaviour
Lazari, A.; Salvan, P.; Cottaar, M.; Papp, D.; van der Werf, O. J.; Johnstone, A.; Sanders, Z.-B.; Sampaio-Baptista, C.; Eichert, N.; Miyamoto, K.; Winkler, A.; Callaghan, M. F.; Nichols, T. E.; Stagg, C. J.; Rushworth, M.; Verhagen, L.; Johansen-Berg, H.
10.1101/2020.12.15.422826 — neuroscience — Posted on 2020-12-15
2025 The timing and impact of psychiatric, cognitive and motor abnormalities in Huntington's disease
McAllister, B.; Gusella, J. F.; Landwehrmeyer, G. B.; Lee, J.-M.; MacDonald, M. E.; Orth, M.; Rosser, A. E.; Williams, N. M.; REGISTRY Investigators of the European Huntington's disease network, ; Holmans, P.; Jones, L.; Massey, T. H.
10.1101/2020.05.26.116798 — neuroscience — Posted on 2020-12-15
2028 Stretch-activated ion channels identified in the touch-sensitive structures of carnivorous Droseraceae plants
Procko, C.; Murthy, S.; Keenan, W. T.; Mousavi, S. A. R.; Dabi, T.; Coombs, A.; Procko, E.; Baird, L.; Patapoutian, A.; Chory, J.
10.1101/2020.12.15.422915 — plant biology — Posted on 2020-12-15
2029 A systematic analysis of rodent models implicates adipogenesis and innate immunity in pathogenesis of fatty liver disease
Im, Y. R.; Hunter, H.; de Gracia Hahn, D.; Duret, A.; Cheah, Q.; Dong, J.; Fairey, M.; Hjalmarsson, C.; Li, A.; Lim, H. K.; McKeown, L.; Mitrofan, C.-G.; Rao, R.; Utukuri, M.; Rowe, I. A.; Mann, J. P.
10.1101/2020.12.15.422799 — physiology — Posted on 2020-12-15
2030 Microbial Species Abundance Distributions Guide Human Population Size Estimation from Sewage Metagenomes
Ling, F.; Chen, L.; Zhang, L.; Yu, X.; Duvallet, C.; Isazadeh, S.; Dai, C.; Park, S.; Frois-Moniz, K.; Duarte, F.; Ratti, C.; Alm, E. J.
10.1101/2020.12.15.390716 — bioinformatics — Posted on 2020-12-15
2033 Plasmodium falciparum serology: A comparison of two protein production methods for analysis of antibody responses by protein microarray
Oulton, T.; Obiero, J.; Rodriguez, I.; Ssewanyana, I.; Dabbs, R. A.; Greenhouse, B.; Drakeley, C.; Felgner, P. L.; Stone, W.; Tetteh, K. K.
10.1101/2020.12.15.422854 — immunology — Posted on 2020-12-15
2035 Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies
Rouet, R.; Mazigi, O.; Walker, G. J.; Langley, D. B.; Sobti, M.; Schofield, P.; Lenthall, H.; Jackson, J.; Ubiparipovic, S.; Henry, J. Y.; Abayasingam, A.; Burnett, D.; Kelleher, A.; Brink, R.; Bull, R. A.; Turville, S.; Stewart, A. G.; Goodnow, C. C.; Rawlinson, W. D.; Christ, D.
10.1101/2020.12.14.422791 — immunology — Posted on 2020-12-15
2036 Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in mouse dorsal and median raphe nucleus
Xu, Z.; Feng, Z.; Zhao, M.-T.; Sun, Q.; Deng, L.; Jia, X.; Jiang, T.; Luo, P.; Chen, W.; Yuan, J.; Li, X.; Gong, H.; Luo, Q.; Li, A.
10.1101/2020.12.15.422858 — neuroscience — Posted on 2020-12-15
2037 Information flow, cell types and stereotypy in a full olfactory connectome
Schlegel, P.; Bates, A. S.; Stürner, T.; Jagannathan, S.; Drummond, N.; Hsu, J.; Seratosa Capdevila, L.; Javier, A.; Marin, E. C.; Barth-Maron, A.; Tamimi, I. F. M.; Li, F.; Rubin, G. M.; Plaza, S. M.; Costa, M.; Jefferis, G. S. X. E.
10.1101/2020.12.15.401257 — neuroscience — Posted on 2020-12-15
2042 A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics
Gossen, J.; Albani, S.; Hanke, A.; Joseph, B. P.; Bergh, C.; Kuzikov, M.; Costanza, E.; Manelfi, C.; Storici, P.; Gribbon, P.; Beccari, A. R.; Talarico, C.; Spyrakis, F.; Lindahl, E.; Zaliani, A.; Carloni, P.; Wade, R. C.; Musiani, F.; Kokh, D. B.; Rossetti, G.
10.1101/2020.12.14.422634 — biophysics — Posted on 2020-12-15
2044 Rapid SARS-CoV-2 Detection and Classification Using Phase Imaging with Computational Specificity
Goswami, N.; He, Y. R.; Deng, Y.-H.; Oh, C.; Sobh, N.; Valera, E.; Bashir, R.; Ismail, N.; Kong, H. J.; Nguyen, T. H.; Best-Popescu, C.; Popescu, G.
10.1101/2020.12.14.422601 — bioengineering — Posted on 2020-12-15
2048 Minnesota peat viromes reveal terrestrial and aquatic niche partitioning for local and global viral populations
ter Horst, A. M.; Santos-Medellin, C.; Sorensen, J. W.; Zinke, L. A.; Wilson, R. M.; Johnston, E. R.; Trubl, G. G.; Pett-Ridge, J.; Blazewicz, S. J.; Hanson, P. J.; Chanton, J. P.; Schadt, C. W.; Kostka, J. E.; Emerson, J. B.
10.1101/2020.12.15.422944 — microbiology — Posted on 2020-12-15
2049 Microbiome and Metabolome driven differentiation of TGF-β producing Tregs leads to Senescence and HIV latency
Sekaly, R.-P.; Ghneim, K.; Sharma, A. A.; Ribeiro, S. P.; Fourati, S.; Ahlers, J.; Kulpa, D.; Xu, X.; Brehm, J.; Talla, A.; Arumugam, S.; Darko, S.; Rodriguez, B.; Shive, C.; Cristescu, R.; Loboda, A.; Balderas, R.; Wang, I.-m.; Hunt, P.; Lamarre, D.; Douek, D.; Hazuda, D.; Lederman, M.; Deeks, S.
10.1101/2020.12.15.422949 — immunology — Posted on 2020-12-15
2052 AdRoit: an accurate and robust method to infer complex transcriptome composition
Yang, T.; Alessandri-Haber, N.; Fury, W.; Schaner, M.; Breese, R.; LaCroix-Fralish, M.; Kim, J.; Adler, C.; Macdonald, L. E.; Atwal, G. S.; Bai, Y.
10.1101/2020.12.14.422697 — bioinformatics — Posted on 2020-12-15
2053 scCODA: A Bayesian model for compositional single-cell data analysis
Buettner, M.; Ostner, J.; Mueller, C. L.; Theis, F. J.; Schubert, B.
10.1101/2020.12.14.422688 — bioinformatics — Posted on 2020-12-15
2055 High-Throughput Developability Assays Enable Library-Scale Identification of Producible Protein Scaffold Variants
Golinski, A. W.; Mischler, K. M.; Laxminarayan, S.; Neurock, N.; Fossing, M.; Pichman, H.; Martiniani, S.; Hackel, B. J.
10.1101/2020.12.14.422755 — bioengineering — Posted on 2020-12-15
2059 A diencephalic circuit for opioid analgesia but not positive reinforcement
Waung, M. W.; Maanum, K. A.; Driscoll, J. R.; O'Brien, C.; Bryant, S.; Mansourian, K.; Morales, M.; Barker, D. J.; Margolis, E. B.
10.1101/2020.12.15.422931 — neuroscience — Posted on 2020-12-15
2062 Vaginal squamous cell carcinoma develops in mice with Arid1a loss and gain of oncogenic Kras
Wang, X.; Praca, M.; Wendel, J. R. H.; Emerson, R.; DeMayo, F.; Lydon, J.; Hawkins, S. M.
10.1101/2020.12.15.422959 — cancer biology — Posted on 2020-12-15
2063 Integral use of immunopeptidomics and immunoinformatics for the characterization of antigen presentation and rational identification of BoLA-DR-presented peptides and epitopes
Fisch, A.; Reynisson, B.; Benedictus, L.; Nicastri, A.; Vasoya, D.; Morrison, I.; Buus, S.; Ferreira, B. R.; Santos, I. K. F. d. M.; Ternette, N.; Connelley, T.; Nielsen, M.
10.1101/2020.12.14.422738 — bioinformatics — Posted on 2020-12-15
2067 Cell-derived hexameric β-amyloid: a novel insight into composition, self-assembly and nucleating properties
Vadukul, D. M.; Vrancx, C.; Burguet, P.; Contino, S.; Suelves, N.; Serpell, L. C.; Quinton, L.; Kienlen-Campard, P.
10.1101/2020.12.15.422916 — biochemistry — Posted on 2020-12-15
2072 DAF-16/FoxO and DAF-12/VDR control cellular plasticity both cell-autonomously and via interorgan signaling
Aghayeva, U.; Bhattacharya, A.; Sural, S.; Jaeger, E.; Churgin, M.; Fang-Yen, C.; Hobert, O.
10.1101/2020.12.15.422925 — genetics — Posted on 2020-12-15
2075 A nuclear role for ARGONAUTE-2 in regulation of neuronal alternative polyadenylation
Ravid, R.; Siany, A.; Rivkin, N.; Eitan, C.; Marmor-Kollet, H.; Yanowski, E.; Savidor, A.; Levin, Y.; Rot, G.; Meister, G.; Hornstein, E.
10.1101/2020.12.15.422806 — cell biology — Posted on 2020-12-15
2077 Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA
Parker, M. T.; Knop, K.; Zacharaki, V.; Sherwood, A. V.; Tome, D.; Yu, X.; Martin, P.; Beynon, J.; Michaels, S.; Barton, G. J.; Simpson, G. G.
10.1101/2020.12.15.422694 — molecular biology — Posted on 2020-12-15
2079 Brain networks and cognitive impairment in Parkinson's disease
Rucco, R.; Lardone, A.; Liparoti, m.; Troisi Lopez, E.; De Micco, R.; Tessitore, A.; Granata, C.; Mandolesi, L.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.12.14.422706 — neuroscience — Posted on 2020-12-15
2081 Regional and age-dependent Effects of Cortical Magnetic Stimulation on Unconstrained Reaching Behavior
Urbin, M. A.; Tian, J.; McKernan, G. P.; Kortzorg, N.; Wyers, L.; Van Halewyck, F.; Boisgontier, M. P.; Levin, O.; Swinnen, S. P.; Jonkers, I.; Wittenberg, G. F.
10.1101/2020.12.14.422725 — neuroscience — Posted on 2020-12-15
2082 Development of an Antiepileptogenesis Drug Screening Platform: Effects of Everolimus and Phenobarbital
Barker-Haliski, M.; Knox, K. M.; Zierath, D. K.; Koneval, Z.; Metcalf, C.; Wilcox, K. S.; White, H. S.
10.1101/2020.12.14.422712 — neuroscience — Posted on 2020-12-15
2086 Integration of Cell Growth and Asymmetric Division During Lateral Root Initiation In Arabidopsis thaliana
Schuetz, L.; Louveaux, M.; Vilches Barro, A.; Bouziri, S.; Cerrone, L.; Wolny, A.; Kreshuk, A.; Hamprecht, F. A.; Maizel, A.
10.1101/2020.12.15.422941 — plant biology — Posted on 2020-12-15
2088 Immunogenomic profile of colorectal cancer response to immune checkpoint blockade
Bortolomeazzi, M.; Keddar, M. R.; Montorsi, L.; Acha-Sagredo, A.; Benedetti, L.; Temelkovski, D.; Choi, S.; Petrov, N.; Todd, K.; Wai, P.; Kohl, J.; Denner, T.; Nye, E.; Goldstone, R.; Ward, S.; Wilson, G. A.; Al Bakir, M.; Swanton, C.; John, S.; Miles, J.; Larijani, B.; Kunene, V.; Fontana, E.; Arkenau, H.-T.; Parker, P. J.; Rodriguez-Justo, M.; Shiu, K.-K.; Spencer, J.; Ciccarelli, F. D.
10.1101/2020.12.15.422831 — cancer biology — Posted on 2020-12-15
2089 DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation
Hou, Z.; Wydorski, P. M.; Perez, V. A.; Mendoza-Oliva, A.; Ryder, B. D.; Mirbaha, H.; Kashmer, O.; Joachimiak, L. A.
10.1101/2020.12.15.422895 — biophysics — Posted on 2020-12-15
2090 From neuron to muscle to movement: a complete biomechanical model of Hydra contractile behaviors
Wang, H.; Swore, J. J.; Sharma, S.; Szymanski, J. R.; Yuste, R.; Daniel, T. L.; Regnier, M.; Bosma, M.; Fairhall, A. L.
10.1101/2020.12.14.422784 — biophysics — Posted on 2020-12-15
2092 SnapHiC: a computational pipeline to map chromatin contacts from single cell Hi-C data
Yu, M.; Abnousi, A.; Zhang, Y.; Li, G.; Lee, L.; Chen, Z.; Fang, R.; Wen, J.; Sun, Q.; Li, Y.; Ren, B.; Hu, M.
10.1101/2020.12.13.422543 — bioinformatics — Posted on 2020-12-15
2093 BiG-MAP: an automated pipeline to profile metabolic gene cluster abundance and expression in microbiomes
Pascal Andreu, V.; Augustijn, H. E.; van den Berg, K.; van der Hooft, J. J. J.; Fischbach, M. A.; Medema, M. H.
10.1101/2020.12.14.422671 — bioinformatics — Posted on 2020-12-15
2098 Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo
Zhu, Z.; Waxman, S.; Wang, B.; Wallace, J.; Schmitt, S. E.; Tyler-Kabara, E.; Ishikawa, H.; Schuman, J. S.; Smith, M. A.; Wollstein, G.; Sigal, I. A.
10.1101/2020.12.14.422760 — bioengineering — Posted on 2020-12-15
2099 Structure-guided microbial targeting of antistaphylococcal prodrugs
Miller, J.; Shah, I. T.; Hatten, J.; Barekatain, Y.; Mueller, E. A.; Moustafa, A. M.; Edwards, R. L.; Dowd, C. S.; Planet, P. J.; Muller, F. L.; Jez, J. M.; Odom John, A. R.
10.1101/2020.12.15.408237 — biochemistry — Posted on 2020-12-15
2100 Highly contiguous assemblies of 101 drosophilid genomes
Kim, B. Y.; Wang, J.; Miller, D. E.; Barmina, O.; Delaney, E. K.; Thompson, A.; Comeault, A. A.; Peede, D.; D'Agostino, E. R. R.; Pelaez, J.; Aguilar, J. M.; Haji, D.; Matsunaga, T.; Armstrong, E. E.; Zych, M.; Ogawa, Y.; Stamenkovic-Radak, M.; Jelic, M.; Veselinovic, M. S.; Tanaskovic, M.; Eric, P.; Gao, J.-j.; Katoh, T. K.; Toda, M. J.; Watabe, H.; Watada, M.; Davis, J. S.; Moyle, L. C.; Manoli, G.; Bertolini, E.; Kostal, V.; Hawley, R. S.; Takahashi, A.; Jones, C. D.; Price, D. K.; Whiteman, N. K.; Kopp, A.; Matute, D. R.; Petrov, D. A.
10.1101/2020.12.14.422775 — evolutionary biology — Posted on 2020-12-15
2101 Widespread introgression across a phylogeny of 155 Drosophila genomes
Suvorov, A.; Kim, B. Y.; Wang, J.; Armstrong, E. E.; Peede, D.; D'Agostino, E. R. R.; Price, D. K.; Wadell, P.; Lang, M.; Courtier-Orgogozo, V.; David, J. R.; Petrov, D.; Matute, D. R.; Schrider, D. R.; Comeault, A. A.
10.1101/2020.12.14.422758 — evolutionary biology — Posted on 2020-12-15
2103 Nutrition or nature: disentangling the complex forces shaping prokaryote pan-genomes
Garza, D. R.; von Meijenfeldt, F. A. B.; van Dijk, B.; Boleij, A.; Huynen, M.; Dutilh, B. E.
10.1101/2020.12.14.422685 — evolutionary biology — Posted on 2020-12-15
2105 Factors contributing to the disease ecology of brown crab (Cancer pagurus) in a temperate marine protected area.
Davies, C. E.; Johnson, A. F.; Wootton, E. C.; Greenwood, S. J.; Clark, K. F.; Vogan, C. L.; Rowley, A. F.
10.1101/2020.12.14.416628 — ecology — Posted on 2020-12-15
2108 CeLaVi: An Interactive Cell Lineage Visualisation Tool
Salvador-Martinez, I.; Grillo, M.; Averof, M.; Telford, M. J.
10.1101/2020.12.14.422765 — developmental biology — Posted on 2020-12-15
2109 Palmitoylation of KChIP3 controls baseline mucin secretion
Cantero-Recasens, G.; Burballa, C.; Duran, M.; Brouwers, N.; Malhotra, V.
10.1101/2020.12.15.422936 — cell biology — Posted on 2020-12-15
2110 Characterization of human embryonic stem cells in animal component-free medium
Machida, M.; Abutani, R.; Miyajima, H.; Sasaki, T.; Abe, Y.; Akutsu, H.; Umezawa, A.
10.1101/2020.12.14.420984 — cell biology — Posted on 2020-12-15
2111 DRAM1 requires PI(3,5)P2 generation by PIKfyve to deliver vesicles and their cargo to endolysosomes
van der Vaart, M.; Banducci-Karp, A.; Forn Cuni, G.; Witt, P. M. M.; Willemse, J. J.; Sanchez, S. M.; Hosseini, R.; Meijer, A. H.
10.1101/2020.12.15.422832 — molecular biology — Posted on 2020-12-15
2115 A novel family of nonribosomal peptides modulate collective behavior in Pseudovibrio bacteria isolated from marine sponges
Ioca, L. P.; Dai, Y.; Kunakom, S.; Diaz-Espinosa, J.; Krunic, A.; Crnkovic, C. M.; Orjala, J.; Sanchez, L. M.; Ferreira, A. G.; Berlinck, R. G.; Eustaquio, A. S.
10.1101/2020.12.15.422899 — microbiology — Posted on 2020-12-15
2117 Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response
Mishra, H. K.; Ying, N. M.; Luis, A.; Wei, H.; Nguyen, M.; Nakhla, T.; Vandenburgh, S.; Alda, M.; Berrettini, W. H.; Brennand, K. J.; Calabrese, J. R.; Coryell, W. H.; Frye, M. A.; Gage, F. H.; Gershon, E. S.; McInnis, M. G.; Nievergelt, C. M.; Nurnberger, J. I.; Shilling, P. D.; Oedegaard, K. J.; Zandi, P. P.; The Pharmacogenomics of Bipolar Disorder Study, ; Kelsoe, J. R.; Welsh, D. K.; McCarthy, M. J.
10.1101/2020.12.14.422616 — neuroscience — Posted on 2020-12-15
2118 Toward asleep DBS: Cortico basal-ganglia neural activity during interleaved propofol/ketamine sedation mimics NREM/REM sleep activity
Guang, J.; Baker, H.; Ben-Yishay Nizri, O.; Firman, S.; Werner-Reiss, U.; Kapuller, V.; Israel, Z.; Bergman, H.
10.1101/2020.12.14.422637 — neuroscience — Posted on 2020-12-15
2120 Total recall: episodic memory retrieval,choice, and memory confidence in the rat
Joo, H. R.; Liang, H.; Chung, J. E.; Geaghan-Breiner, C.; Fan, J. L.; Nachman, B.; Kepecs, A.; Frank, L. M.
10.1101/2020.12.14.420174 — neuroscience — Posted on 2020-12-15
2122 Specialized coding patterns among dorsomedial prefrontal neuronal ensembles during conditioned reward seeking.
Grant, R. I.; Doncheck, E. M.; Vollmer, K. M.; Winston, K. T.; Romanova, E. V.; Siegler, P. N.; Bowen, C. W.; Otis, J. M.
10.1101/2020.12.14.422672 — neuroscience — Posted on 2020-12-15
2125 Cholecystokinin-like Peptide Mediates Satiety by Inhibiting Sugar Attraction
Guo, D.; Zhang, Y.-j.; Zhang, S.; Li, J.; Guo, C.; Pan, Y.; Liu, C.-X.; Jia, Y.-L.; Li, C.-Y.; Ma, J.-Y.; Nassel, D.; Gao, C.-F.; Wu, S.-F.
10.1101/2020.12.14.419390 — neuroscience — Posted on 2020-12-15
2128 Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer
Fathi, M.; Joseph, R.; Adolacion, J. R. T.; Martinez-Paniagua, M.; An, X.; Gabrusiewicz, K.; Mani, S. A.; Varadarajan, N.
10.1101/2020.12.14.422613 — cancer biology — Posted on 2020-12-15
2130 Proteomic profiling of breast cancer cell lines and models
Kalocsay, M.; Berberich, M.; Everley, R.; Nariya, M.; Chung, M.; Gaudio, B.; Victor, C.; Bradshaw, G.; Hafner, M.; Sorger, P. K.; Mills, C.; Subramanian, K.
10.1101/2020.12.15.422823 — cancer biology — Posted on 2020-12-15
2132 Collective migration of human osteoblasts in direct current electric field
Dawson, J. E.; Sellmann, T.; Porath, K.; Bader, R.; van Rienen, U.; Appali, R.; Koehling, R.
10.1101/2020.12.15.422893 — biophysics — Posted on 2020-12-15
2136 The evolutionary history of topological variations in the CPA/AT superfamily
Govindarajan, S.; Bassot, C.; Lamb, J.; Shu, N.; Huang, Y.; Elofsson, A.
10.1101/2020.12.13.422607 — bioinformatics — Posted on 2020-12-15
2137 IOBR: Multi-omics Immuno-Oncology Biological Research to decode tumor microenvironment and signatures
Zeng, D.; Ye, Z.; Yu, G.; Wu, J.; Xiong, Y.; Zhou, R.; Qiu, W.; Huang, N.; Sun, L.; Bin, J.; Liao, Y.; Shi, M.; Liao, W.
10.1101/2020.12.14.422647 — bioinformatics — Posted on 2020-12-15
2139 Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death
DELEHOUZE, C.; COMTE, A.; HAUTEVILLE, M.; GOEKJIAN, P. G.; DIMANCHE-BOITREL, M.-T.; ROUSSELOT, M.; BACH, S.
10.1101/2020.12.15.422885 — biochemistry — Posted on 2020-12-15
2145 IFT88 transports Gucy2d, a guanylyl cyclase, to maintain sensory cilia function in Drosophila
Werner, S.; Zitouni, S.; Okenve-Ramos, P.; Mendonca, S.; Sporbert, A.; Spalthoff, C.; Gopfert, M. C.; Jana, S. C.; Bettencourt-Dias, M.
10.1101/2020.12.15.417840 — cell biology — Posted on 2020-12-15
2153 Circumventing drug treatment? Polyethylenimine functionalized nanoparticles inherently and selectively kill patient-derived glioblastoma stem cells
Prabhakar, N.; Merisaari, J.; Le Joncour, V.; Peurla, M.; Sen Karaman, D.; Casals, E.; Laakkonen, P.; Westermarck, J.; Rosenholm, J.
10.1101/2020.12.14.422717 — cancer biology — Posted on 2020-12-15
2154 STUB1 is an intracellular checkpoint for interferon gamma sensing
Ng, S.; Lim, S.; Sim, A. C. N.; Mangadu, R.; Lau, A.; Zhang, C.; Chandramohan, A.; Lim, U.-M.; Ho, S. S. W.; Chang, S. C.; Gopal, P.; Hong, L. Z.; Loboda, A.; Fernandis, A. Z.; Phan, U.; Henry, B.; Partridge, A. W.
10.1101/2020.12.14.420539 — cancer biology — Posted on 2020-12-15
2156 Shifts from pulled to pushed range expansions caused by reduction of landscape connectivity
Dahirel, M.; Bertin, A.; Haond, M.; Blin, A.; Lombaert, E.; Calcagno, V.; Fellous, S.; Mailleret, L.; Malausa, T.; Vercken, E.
10.1101/2020.05.13.092775 — ecology — Posted on 2020-12-15
2158 Profound Treg perturbations correlate with COVID-19 severity
Galvan-Pena, S.; Leon, J.; Chowdhary, K.; Michelson, D. A.; Vijaykumar, B.; Yang, L.; Magnuson, A.; Manickas-Hill, Z.; Piechocka-Trocha, A.; Worrall, D. P.; Hall, K. E.; Ghebremichael, M.; Walker, B. D.; Li, J. Z.; Yu, X. G.; MGH COVID-19 Collection & Processing Team, ; Mathis, D.; Benoist, C.
10.1101/2020.12.11.416180 — immunology — Posted on 2020-12-15
2159 In Vitro Activity of Itraconazole Against SARS-CoV-2
Van Damme, E.; De Meyer, S.; Bojkova, D.; Ciesek, S.; Cinatl, J.; De Jonghe, S.; Jochmans, D.; Leyssen, P.; Buyck, C.; Neyts, J.; Van Loock, M.
10.1101/2020.11.13.381194 — pharmacology and toxicology — Posted on 2020-12-15
2161 Two mutations in the SARS-CoV-2 spike protein and RNA polymerase complex are associated with COVID-19 mortality risk
Hahn, G.; Wu, C. M.; Lee, S.; Hecker, J.; Lutz, S. M.; Haneuse, S.; Qiao, D.; DeMeo, D.; Choudhary, M. C.; Etemad, B.; Mohammadi, A.; Esmaeilzadeh, E.; Cho, M. H.; Tanzi, R. E.; Li, J. Z.; Randolph, A. G.; Laird, N. M.; Weiss, S. T.; Silverman, E. K.; Ribbeck, K.; Lange, C.
10.1101/2020.11.17.386714 — genomics — Posted on 2020-12-15
2162 Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
Guiglielmoni, N.; Houtain, A.; Derzelle, A.; van Doninck, K.; Flot, J.-F.
10.1101/2020.03.16.993428 — genomics — Posted on 2020-12-15
2164 Novel virus-like particle vaccine encoding the circumsporozoite protein of Plasmodium falciparum is immunogenic and induces functional antibody responses
Kurtovic, L.; Wetzel, D.; Reiling, L.; Drew, D. R.; Palmer, C.; Kouskousis, B.; Hanssen, E.; Wines, B. D.; Hogarth, P. M.; Suckow, M.; Jenzelewski, V.; Piontek, M.; Chan, J.-A.; Beeson, J.
10.1101/2020.12.14.422617 — immunology — Posted on 2020-12-15
2165 Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion ΔH69/V70
Kemp, S.; Datir, R.; Collier, D.; Ferreira, I.; Carabelii, A.; Harvey, W.; Robertson, D. L.; Gupta, R. K.
10.1101/2020.12.14.422555 — microbiology — Posted on 2020-12-15
2166 Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium
Israeli, A.; Burko, Y.; Shleizer-Burko, S.; Daphne Zelnik, I.; Sela, N.; R. Hajirezaei, M.; Fernie, A. R.; Tohge, T.; Ori, N.; Bar, M.
10.1101/2020.12.14.422551 — plant biology — Posted on 2020-12-15
2168 A gene regulatory network critical for axillary bud dormancy directly controlled by Arabidopsis BRANCHED1
van Es, S. W.; Munoz-Gasca, A.; Romero-Campero, F. J.; Gonzalez-Grandio, E.; de los Reyes, P.; Tarancon, C.; van Dijk, A. D. J.; van Esse, W.; Angenent, G. C.; Immink, R.; Cubas, P.
10.1101/2020.12.14.394403 — plant biology — Posted on 2020-12-15
2173 The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis
Scheer, H.; de Almeida, C.; Ferrier, E.; Simonnot, Q.; Poirier, L.; Pflieger, D.; Sement, F. M.; Koechler, S.; Piermaria, C.; Krawczyk, P.; Mroczek, S.; Chicher, J.; Kuhn, L.; Dziembowski, A.; Hammann, P.; Zuber, H.; Gagliardi, D.
10.1101/2020.05.26.114322 — molecular biology — Posted on 2020-12-15
2175 Cell type specific information transfer for sparse coding
Zeldenrust, F.; Calcini, N.; Yan, X.; Bijlsma, A.; Celikel, T.
10.1101/2020.11.06.371658 — neuroscience — Posted on 2020-12-15
2176 Image3C: a multimodal image-based and label independent integrative method for single-cell analysis
Accorsi, A.; Box, A. C.; Peuss, R.; Wood, C.; Sanchez Alvarado, A.; Rohner, N.
10.1101/603035 — zoology — Posted on 2020-12-15
2177 Multi-model evaluation of phenology prediction for wheat in Australia
Wallach, D.; Palosuo, T.; Thorburn, P.; Hochman, Z.; Andrianasolo, F.; Asseng, S.; Basso, B.; Buis, S.; Crout, N.; Dumont, B.; Ferrise, R.; Gaiser, T.; Gayler, S.; Hiremath, S.; Hoek, S.; Horan, H.; Hoogenboom, G.; Huang, M.; Jabloun, M.; Jansson, P.-E.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Luo, Q.; Maestrini, B.; Moriondo, M.; Padovan, G.; Olesen, J. E.; Poyda, A.; Priesack, E.; Pullens, J. W. M.; Qian, B.; Schütze, N.; Shelia, V.; Souissi, A.; Specka, X.; Srivastava, A. K.; Stella, T.; Streck, T.; Trombi, G.; Wallor, E.; Wang, J.; Weber, T. K. D.; Weihermüller, L.
10.1101/2020.06.06.133504 — plant biology — Posted on 2020-12-15
2179 Machine learning predicts immunoglobulin light chain toxicity through somatic mutations
Garofalo, M.; Piccoli, L.; Romeo, M.; Barzago, M. M.; Ravasio, S.; Foglierini, M.; Matkovic, M.; Sgrignani, J.; De Gasparo, R.; Prunotto, M.; Varani, L.; Diomede, L.; Michielin, O.; Lanzavecchia, A.; Cavalli, A.
10.1101/849901 — bioinformatics — Posted on 2020-12-15
2183 Body site-specific and disease-specific virulome in the human microbiome
Liu, F.; Dong, W.; Guo, Y.; Xiong, Q.; Lu, N.; Song, X.; Xue, Y.; Cao, D.; Fan, X.; Fang, Y.; Li, Z.; Cao, J.; Wang, Y.; Yang, G.; Gao, G. F.; Zhao, F.; Zhu, B.
10.1101/2020.12.13.403006 — genomics — Posted on 2020-12-14
2184 Non-coding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability
Ding, B.; Liu, Y.; Liu, Z.; Zheng, L.; Xu, P.; Chen, Z.; Wu, P.; Zhao, Y.; Pan, Q.; Guo, Y.; Wei, W.; Wang, W.
10.1101/2020.12.13.422541 — genetics — Posted on 2020-12-14
2186 A cytokine network balance influences the fate of Leishmania (Viannia) braziliensis infection in a cutaneous leishmaniasis hamster model
Paiva, M.; Ribeiro Romao, R. P.; Resende-Vieira, L.; Braga-Gomes, T.; Oliveira, M. P.; Saavedra, A. F.; Silva-Couto, L.; Albuquerque, H. G.; Moreira, O. P.; Pinto, E. F.; Da-Cruz, A. M.; Gomes da Silva, A.
10.1101/2020.12.14.422666 — immunology — Posted on 2020-12-14
2187 Removal of Scanner Effects in Covariance Improves Multivariate Pattern Analysis in Neuroimaging Data
Chen, A. A.; Beer, J. C.; Tustison, N. J.; Cook, P. A.; Shinohara, R. T.; Shou, H.
10.1101/858415 — neuroscience — Posted on 2020-12-14
2189 Thrombospondin-4 mediates hyperglycemia- and TGF-beta-induced inflammation in breast cancer
Muppala, S.; Xiao, R.; Gajeton, J.; Verbovetskiy, D.; Krukovets, I.; Stenina-Adognravi, O.
10.1101/2020.01.03.894436 — cancer biology — Posted on 2020-12-14
2190 Deep learning classification of canine behavior using a single collar-mounted accelerometer: Real-world validation
Chambers, R. D.; Yoder, N. C.; Carson, A.; Junge, C.; Allen, D.; Prescott, L. M.; Bradley, S.; Wymore, G.; Lloyd, K.; Lyle, S.
10.1101/2020.12.14.422660 — animal behavior and cognition — Posted on 2020-12-14
2195 Effects of Ca2+ on encystment and growth in Scrippsiella trochoidea
Wang, Z.; Feng, W.; Cao, J.; Zhang, H.; Zhang, D.; Qian, J.; Xu, H.; Hao, Z.
10.1101/2020.12.14.422664 — ecology — Posted on 2020-12-14
2197 A high-throughput metabolic microarray assay reveals antibacterial effects of black and red raspberries and blackberries against Helicobacter pylori infection
Goodman, C.; Lyon, K.; Scotto, A.; Roe, M. M.; Moghimpour, F.; Sebrell, T. A.; Gentry, A. B.; Bala, G.; Stoner, G.; Bimczok, D.
10.1101/2020.12.14.422663 — microbiology — Posted on 2020-12-14
2198 Transcriptional activity differentiates families of Marine Group II Euryarchaeota in the coastal ocean
Damashek, J.; Okotie-Oyekan, A. O.; Gifford, S. M.; Vorobev, A.; Moran, M. A.; Hollibaugh, J. T.
10.1101/2020.09.16.299958 — microbiology — Posted on 2020-12-14
2199 Pre-existing SIV infection increases expression of T cell markers associated with activation during early Mycobacterium tuberculosis co-infection and impairs TNF responses in granulomas
Larson, E.; Ellis, A. L.; Rodgers, M. A.; Balgeman, A. J.; Moriarty, R. V.; Ameel, C.; Baranowski, T.; Tomko, J.; Causgrove, C.; Maiello, P.; OConnor, S. L.; Scanga, C. A.
10.1101/2020.12.14.422668 — immunology — Posted on 2020-12-14
2200 Mycobacterial infection-induced miR-206 inhibits protective neutrophil recruitment via the CXCL12/CXCR4 signalling axis
Wright, K.; de Silva, K.; Plain, K. M.; Purdie, A. C.; Blair, T. A.; Duggin, I. G.; Britton, W. J.; Oehlers, S. H.
10.1101/2020.12.14.422665 — immunology — Posted on 2020-12-14
2201 Hippocampal cells multiplex positive and negative engrams
Shpokayte, M.; McKissick, O.; Yuan, B.; Rahsepar, B.; Fernandez, F. R.; Ruesch, E. A.; Grella, S. L.; White, J. A.; Liu, X. S.; Ramirez, S.
10.1101/2020.12.11.419887 — neuroscience — Posted on 2020-12-14
2207 Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration
Cheng, Y.; Yin, Y.; Zhang, A.; Berstein, A. M.; Kawaguchi, R.; Gao, K.; Potter, K.; Ao, Y.; Gilbert, H.-Y.; Ou, J.; Fricano-Kugler, C. J.; Goldberg, J. L.; Woolf, C. J.; Sofroniew, M. V.; Benowitz, L. I.; Geschwind, D. H.
10.1101/2020.12.13.413104 — neuroscience — Posted on 2020-12-14
2208 Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice
Bennett, C.; Green, J.; Ciancio, M.; Goral, J.; Pitstick, L.; Pytynia, M.; Meyer, A.; Kwatra, N.; Jadavji, N. M.
10.1101/2020.12.13.422535 — neuroscience — Posted on 2020-12-14
2214 Functional Transcriptome Analysis of Bladder Cancer Cell Lines Persistently Infected with Oncolytic Newcastle Disease Virus
Ahmad, U.; Thirumorthy, A.; Chau, D. M.; Chia, S. L.; Yusoff, K.; Abdullah, S.; Chan, S. C.; Veerakumarasivam, A.
10.1101/2020.12.14.422610 — cancer biology — Posted on 2020-12-14
2215 Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia
Demaree, B.; Delley, C. L.; Vasudevan, H. N.; Peretz, C. A. C.; Ruff, D.; Smith, C. C.; Abate, A. R.
10.1101/2020.02.26.967133 — cancer biology — Posted on 2020-12-14
2217 Crystal structure of prototype foamy virus (PFV) protease-reverse transcriptase fusion (PR-RT) reveals conformational plasticity: implications for function
Harrison, J. J. E. K.; Tuske, S.; Das, K.; Ruiz, F. X.; Bauman, J. D.; Boyer, P.; DeStefano, J. J.; Hughes, S. H.; Arnold, E.
10.1101/2020.11.23.395087 — biophysics — Posted on 2020-12-14
2218 A Machine Learning approach for assessing drug development risk
Vergetis, V.; Liaropoulos, G.; Georganaki, M.; Dimakakos, A.; Skaltsas, D.; Gorgoulis, V. G.; Tsirigos, A.
10.1101/2020.10.08.331926 — bioinformatics — Posted on 2020-12-14
2219 Vertical-junction Photodiodes for Smaller Pixels in Retinal Prostheses
Huang, T. W.; Kamins, T. I.; Chen, Z. C.; Wang, B.-Y.; Bhuckory, M. B.; Galambos, L.; Ho, E.; Ling, T.; Afshar, S.; Shin, A.; Zuckerman, V.; Harris, J. S.; Mathieson, K.; Palanker, D.
10.1101/2020.10.28.353128 — bioengineering — Posted on 2020-12-14
2221 FGF2 disruption enhances thermogenesis in brown and beige fat to protect against obesity and hepatic steatosis
Li, H.; Zhang, X.; Huang, C.; Liu, H.; Liu, S.; Zhang, Q.; Dong, M.; Hou, M.; Liu, Y.; Lin, H.
10.1101/2020.12.02.407650 — cell biology — Posted on 2020-12-14
2222 Sniffing the Human Body-Volatile Hexadecanal Blocks Aggression in Men but Triggers Aggression in Women
Mishor, E.; Amir, D.; Weiss, T.; Honigstein, D.; Weissbrod, A.; Livne, E.; Gorodisky, L.; Karagach, S.; Ravia, A.; Snitz, K.; Karawani, D.; Zirler, R.; Weissgross, R.; soroka, T.; Endevelt-Shapira, Y.; Agron, S.; Rozenkrantz, L.; Reshef, N.; Furman-Haran, E.; Breer, H.; Strotmann, J.; Sobel, N.
10.1101/2020.09.29.318287 — neuroscience — Posted on 2020-12-14
2223 Collegiate athlete brain data for white matter mapping and network neuroscience
Caron, B.; Stuck, R.; McPherson, B.; Bullock, D.; Kitchell, L.; Faskowitz, J.; Kellar, D.; Cheng, H.; Newman, S.; Port, N.; Pestilli, F.
10.1101/2020.08.25.267005 — neuroscience — Posted on 2020-12-14
2225 Receptors, circuits and neural dynamics for prediction
Mohanta, S.; Afrasiabi, M.; Casey, C.; Tanabe, S.; Redinbaugh, M. J.; Kambi, N. A.; Phillips, J. M.; Polyakov, D.; Filbey, W.; Austerweil, J. L.; Sanders, R. D.; Saalmann, Y. B.
10.1101/2020.01.06.896589 — neuroscience — Posted on 2020-12-14
2230 miR-467 Prevents Inflammation And Insulin Resistance In Response To Hyperglycemia
Gajeton, J.; Krukovets, I.; Yendamuri, R.; Verbovetskiy, D.; Vasanji, A.; Sul, L.; Stenina-Adognravi, O.
10.1101/666545 — physiology — Posted on 2020-12-14
2231 Paracrine behaviors arbitrate parasite-like interactions between tumor subclones
Noble, R. J.; Walther, V.; Roumestand, C.; Hibner, U.; Hochberg, M. E.; Lassus, P.
10.1101/2020.12.14.422649 — cancer biology — Posted on 2020-12-14
2235 Long read sequencing of 3,622 Icelanders provides insight into the role of structural variants in human diseases and other traits
Beyter, D.; Ingimundardottir, H.; Oddson, A.; Eggertsson, H. P.; Bjornsson, E.; Jonsson, H.; Atlason, B. A.; Kristmundsdottir, S.; Mehringer, S.; Hardarson, M. T.; Gudjonsson, S. A.; Magnusdottir, D. N.; Jonasdottir, A.; Jonasdottir, A.; Kristjansson, R. P.; Sverrisson, S. T.; Holley, G.; Palsson, G.; Stefansson, O. A.; Eyjolfsson, G.; Olafsson, I.; Sigurdardottir, O.; Torfason, B.; Masson, G.; Helgason, A.; Thorsteinsdottir, U.; Holm, H.; Gudbjartsson, D. F.; Sulem, P.; Magnusson, O. T.; Halldorsson, B. V.; Stefansson, K.
10.1101/848366 — genetics — Posted on 2020-12-14
2238 Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling
Konopelski, S. E.; Susman, M. W.; Kunz, R. C.; Tan, J.; Cohen, M. D.; Okada, K.; Lamb, H.; Choi, S. S.; Karuna, E. P.; Scales, M. K.; Gygi, S. P.; Greenberg, M. E.; Ho, H.-Y. H.
10.1101/2020.06.22.163790 — developmental biology — Posted on 2020-12-14
2239 Fetal estrogens are not involved in sex determination but critical for early ovarian differentiation in rabbits.
Jolivet, G.; Daniel-Carlier, N.; Harscoet, E.; Airaud, E.; Dewaele, A.; Pierson, C.; Giton, F.; Boulanger, L.; Daniel, N.; Mandon-Pepin, B.; Pannetier, M.; Pailhoux, E.
10.1101/2020.12.13.419770 — developmental biology — Posted on 2020-12-14
2240 Plk4 triggers autonomous de novo centriole biogenesis and maturation
Nabais, C.; Pessoa, D.; de-Carvalho, J.; van Zanten, T.; Duarte, P.; Mayor, S.; Carneiro, J.; Telley, I. A.; Bettencourt Dias, M.
10.1101/2020.04.29.068650 — cell biology — Posted on 2020-12-14
2241 Maladaptive oxidative stress cascade drives type I interferon hyperactivity in TNF activated macrophages promoting necrosis in murine tuberculosis granulomas
Brownhill, E.; Yabaji, S. M.; Zhernovkov, V.; Rukhlenko, O. S.; Seidel, K.; Bhattacharya, B.; Chatterjee, S.; Chen, H. A.; Crossland, N.; Bishai, W.; Kholodenko, B. N.; Gimelbrant, A.; Kobzik, L.; Kramnik, I.
10.1101/2020.12.14.422743 — immunology — Posted on 2020-12-14
2244 Heroin self-administration and extinction increases prelimbic cortical astroglia-synapse proximity and alters dendritic spine morphometrics that are reversed by N-acetylcysteine
Siemsen, B. M.; Hooker, K. N.; Carpenter, E. A.; Prescott, M. E.; Brock, A. G.; Leath, M. N.; McFaddin, J. A.; McGinty, J. F.; Scofield, M. D.
10.1101/2020.05.21.108530 — neuroscience — Posted on 2020-12-14
2247 DAJIN-assisted multiplex genotyping to validate the outcomes of CRISPR-Cas-based genome editing
Kuno, A.; Ikeda, Y.; Ayabe, S.; Kato, K.; Sakamoto, K.; Suzuki, S.; Morimoto, K.; Wakimoto, A.; Mikami, N.; Ishida, M.; Iki, N.; Hamada, Y.; Takemura, M.; Daitoku, Y.; Tanimoto, Y.; Dinh, T. T.; Murata, K.; Hamada, M.; Yoshiki, A.; Sugiyama, F.; Takahashi, S.; Mizuno, S.
10.1101/2020.12.14.422641 — genomics — Posted on 2020-12-14
2248 The SEQC2 Epigenomics Quality Control (EpiQC) Study: Comprehensive Characterization of Epigenetic Methods, Reproducibility, and Quantification
Foox, J.; Nordlund, J.; Lalancette, C.; Gong, T.; Lacey, M.; Lent, S.; Langhorst, B. W.; Ponnaluri, V. K. C.; Williams, L.; Padmamabhan, K.; Cavalcante, R. G.; Lundmark, A.; Butler, D.; Gurvitch, J. M.; Greally, J. M.; Suzuki, M.; Menor, M.; Nasu, M.; Alonso, A.; Sheridan, C.; Scherer, A.; Bruinsma, S.; Golda, G.; Muszynska, A.; Łabaj, P. P.; Campbell, M. A.; Wos, F.; Raine, A.; Liljedahl, U.; Axelsson, T.; Wang, C.; Chen, Z.; Yang, Z.; Li, J.; Yang, X.; Wang, H.; Melnick, A.; Guo, S.; Blume, A.; Franke, V.; Ibanez de Caceres, I.; Rodriguez-Antolin, C.; Rosas, R.; Davis, J. W.; Ishii, J.; Megh
10.1101/2020.12.14.421529 — genomics — Posted on 2020-12-14
2251 Stable QTL for malate levels in ripe fruit and their transferability across Vitis species
Reshef, N.; Karn, A.; Manns, D. C.; Mansfield, A. K.; Cadle-Davidson, L.; Reisch, B.; Sacks, G. L.
10.1101/2020.12.14.422701 — genetics — Posted on 2020-12-14
2253 Lineage-specific control of convergent differentiation by a Forkhead repressor
Mizeracka, K.; Rogers, J. M.; Rumley, J. D.; Shaham, S.; Bulyk, M. L.; Murray, J. I.; Heiman, M. G.
10.1101/758508 — developmental biology — Posted on 2020-12-14
2254 A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs
Nguyen, T.; Phan, K. L.; Kreitler, D. E.; Andrews, L. C.; Gabelli, S. B.; Kozakov, D.; Jakoncic, J.; Sweet, R. M.; Soares, A.; Bernstein, H. J.
10.1101/2020.12.14.422680 — molecular biology — Posted on 2020-12-14
2256 Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion ΔH69/V70
Kemp, S.; Datir, R.; Collier, D.; Ferreira, I.; Carabelii, A.; Harvey, W.; Robertson, D. L.; Gupta, R. K.
10.1101/2020.12.14.422555 — microbiology — Posted on 2020-12-14
2257 Public good exploitation in natural bacterioplankton communities
Pollak, S.; Gralka, M.; Sato, Y.; Schwartzman, J. A.; Lu, L.; Cordero, O. X.
10.1101/2020.12.13.422583 — microbiology — Posted on 2020-12-14
2258 Exploring the microbiome-wide lysine acetylation, succinylation and propionylation in human gut microbiota
Zhang, X.; Cheng, K.; Ning, Z.; Mayne, J.; Walker, K.; Chi, H.; Farnsworth, C.; Lee, K.; Figeys, D.
10.1101/2020.12.14.422746 — microbiology — Posted on 2020-12-14
2259 Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity
Doyle, D. Z.; Lam, M. M.; Qalieh, A.; Qalieh, Y.; Sorel, A.; Funk, O. H.; Kwan, K. Y.
10.1101/2020.12.14.422645 — neuroscience — Posted on 2020-12-14
2260 Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function
Avagliano Trezza, R.; Punt, M.; Mientjes, E.; van den Berg, M.; Zampeta, I.; de Graaf, I. J.; van der Weegen, Y.; Demmers, J. A.; Elgersma, Y.; Distel, B.
10.1101/2020.12.14.422704 — neuroscience — Posted on 2020-12-14
2261 The infection-tolerant mammalian reservoir of Lyme disease and other zoonoses broadly counters the inflammatory effects of endotoxin
Balderrama-Gutierrez, G.; Milovic, A.; Cook, V. J.; Islam, M. N.; Zhang, Y.; Kiaris, H.; Belisle, J. T.; Mortazavi, A.; Barbour, A. G.
10.1101/2020.12.13.422519 — systems biology — Posted on 2020-12-14
2263 Engineering clinically-approved drug gated CAR circuits
Li, H.-S.; Wong, N. M.; Tague, E.; Ngo, J. T.; Khalil, A. S.; Wong, W. W.
10.1101/2020.12.14.419812 — synthetic biology — Posted on 2020-12-14
2266 Mutational and biophysical robustness in a pre-stabilized monobody
Chandler, P. G.; Tan, L. L.; Porebski, B. T.; Green, J. S.; Riley, B. T.; Broendum, S. S.; Hoke, D. E.; Falconer, R. J.; Munro, T. P.; Buckle, M.; Jackson, C. J.; Buckle, A. M.
10.1101/2020.12.14.422768 — biochemistry — Posted on 2020-12-14
2268 SARS-CoV-2 Requires Cholesterol for Viral Entry and Pathological Syncytia Formation
Sanders, D. W.; Jumper, C. C.; Ackerman, P. J.; Bracha, D.; Donlic, A.; Kim, H.; Kenney, D.; Castello-Serrano, I.; Suzuki, S.; Tamura, T.; Tavares, A. H.; Saeed, M.; Holehouse, A. S.; Ploss, A.; Levental, I.; Douam, F.; Padera, R. F.; Levy, B. D.; Brangwynne, C. P.
10.1101/2020.12.14.422737 — cell biology — Posted on 2020-12-14
2273 Microbe-seq: high-throughput, single-microbe genomics with strain resolution, applied to a human gut microbiome
Zheng, W.; Zhao, S.; Yin, Y.; Zhang, H.; Needham, D. M.; Evans, E. D.; Dai, C. L.; Lu, P. J.; Alm, E. J.; Weitz, D. A.
10.1101/2020.12.14.422699 — microbiology — Posted on 2020-12-14
2279 Proteomic characterization of pilot scale hot-water extracts from the industrial carrageenan red seaweed Eucheuma denticulatum
Gregersen, S.; Pertseva, M.; Marcatili, P.; Holdt, S. L.; Jacobsen, C.; Garcia-Moreno, P. J.; Hansen, E. B.; Overgaard, M. T.
10.1101/2020.12.14.422673 — biochemistry — Posted on 2020-12-14
2281 Genetic and Epigenetic Regulation of Skeletal Muscle Ribosome Biogenesis with Exercise
Figueiredo, V. C.; Wen, Y.; Alkner, B.; Fernandez-Gonzalo, R.; Norrbom, J.; Vechetti, I. J.; Valentino, T.; Mobley, C. B.; Zentner, G. E.; Peterson, C. A.; McCarthy, J. J.; Murach, K. A.; von Walden, F.
10.1101/2020.12.14.422642 — cell biology — Posted on 2020-12-14
2284 Hepatitis C Virus Drugs Simeprevir and Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV-2 Replication in Cell Culture
Bafna, K.; White, K.; Harish, B.; Rosales, R.; Ramelot, T. A.; Acton, T. B.; Moreno, E.; Kehrer, T.; Royer, C. A.; Garcia-Sastre, A.; Krug, R. M.; Montelione, G. T.
10.1101/2020.12.13.422511 — biochemistry — Posted on 2020-12-14
2285 Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products in vitro
He, C.-L.; Huang, L.-Y.; Wang, K.; Gu, C.-J.; Hu, J.; Zhang, G.-J.; Xu, W.; Xie, Y.-H.; Tang, N.; Huang, A.-L.
10.1101/2020.12.13.420406 — microbiology — Posted on 2020-12-14
2286 Neuroinvasion and encephalitis following intranasal inoculation of SARS-CoV-2 in K18-hACE2 mice
Kumari, P.; Rothan, H. A.; Natekar, J. P.; Stone, S.; Pathak, H.; Strate, P. G.; Arora, K.; Brinton, M. A.; Kumar, M.
10.1101/2020.12.14.422714 — microbiology — Posted on 2020-12-14
2287 Profiling of oral microbiota and cytokines in COVID-19 patients
Iebba, V.; Zanotta, N.; Campisciano, G.; Zerbato, V.; Di Bella, S.; Cason, C.; Morassut, S.; Luzzati, R.; Confalonieri, M.; Palamara, A. T.; Comar, M.
10.1101/2020.12.13.422589 — microbiology — Posted on 2020-12-14
2293 Large-scale geographic survey provides insights into the colonization history of a major aphid pest on its cultivated apple host in Europe, North America and North Africa
Olvera-Vazquez, S. G.; Remoue, C.; Venon, A.; Rousselet, A.; Grandcolas, O.; Azrine, M.; Momont, L.; Galan, M.; Benoit, L.; David, G.; Alhmedi, A.; Belien, T.; Alins, G.; Franck, P.; Haddioui, A.; Jacobsen, S. K.; Andreev, R.; Simon, S.; Sigsgaard, L.; Guibert, E.; Tournant, L.; Gazel, F.; Mody, K.; Khachtib, Y.; Roman, A.; Ursu, T. M.; Zakharov, I. A.; Belcram, H.; Harry, M.; Roth, M.; Simon, J. C.; Oram, S.; Ricard, J. M.; Agnello, A.; Beers, E. H.; Engelman, J.; Balti, I.; Salhi-Hannachi, A.; Zhang, H.; Tu, H.; Mottet, C.; Barres, B.; Degrave, A.; Razmjou, J.; Giraud, T.; Falque, M.; Dapena
10.1101/2020.12.11.421644 — evolutionary biology — Posted on 2020-12-14
2297 Deregulation of brain endothelial CD2AP in Alzheimer's disease impairs Reelin-mediated neurovascular coupling
Vandal, M.; Gunn, C.; Institoris, A.; Bourassa, P.; Mishra, R. C.; Peringod, G.; Belzil, C.; Jiang, Y.; Reveret, L.; Tremblay, C.; Hashem, M.; Nicola, W.; Korbelin, J.; Dunn, J. F.; Braun, A. P.; Bennett, D. A.; Gordon, G. R.; Calon, F.; Nguyen, M. D.
10.1101/2020.12.10.419598 — neuroscience — Posted on 2020-12-14
2300 Functional Transcriptome Analysis of Bladder Cancer Cell Lines Persistently Infected with Oncolytic Newcastle Disease Virus
Ahmad, U.; Thirumorthy, A.; Chau, D. M.; Chia, S. L.; Yusoff, K.; Abdullah, S.; Chan, S. C.; Veerakumarasivam, A.
10.1101/2020.12.14.422610 — cancer biology — Posted on 2020-12-14
2301 Mechanically Matched Silicone Brain Implants Reduce Brain Foreign Body Response
Zhang, E.; Alameri, A.; Clement, J.-P.; Ng, A.; Kennedy, T. E.; Juncker, D.
10.1101/2020.12.13.422566 — bioengineering — Posted on 2020-12-14
2302 Complement receptor 3 forms a compact high affinity complex with iC3b
Jensen, R. K.; Bajic, G.; Sen, M.; Springer, T.; Vorup-Jensen, T.; Andersen, G. R.
10.1101/2020.04.15.043133 — biochemistry — Posted on 2020-12-14
2305 Oxidized LDL but not angiotensin II induces the interaction between LOX-1 and AT1 receptors
Lin, L.; Zhou, N.; Kang, L.; Wang, Q.; Wu, J.; Wang, X.; Yang, C.; Zhang, G.; Chen, Y.; Jiang, H.; Chen, R.; Yang, X.; Sun, A.; Gong, H.; Ren, J.; Akazawa, H.; KOMURO, I.; Ge, J.; Yang, C.; Zou, Y.
10.1101/2020.12.14.422633 — cell biology — Posted on 2020-12-14
2307 Heterochiasmy facilitated the establishment of gsdf as a novel sex determining gene in Atlantic halibut
Edvardsen, R. B.; Wallerman, O.; Furmanek, T.; Kleppe, L.; Jern, P.; Wallberg, A.; Kjaerner-Semb, E.; Maehle, S.; Olausson, S. K.; Sundstrom, E.; Harboe, T.; Mangor-Jensen, R.; Mogster, M.; Perrichon, P.; Norberg, B.; Rubin, C.-J.
10.1101/2020.11.24.396218 — genomics — Posted on 2020-12-14
2308 Using genetic variation to disentangle the complex relationship between food intake and health outcomes.
Pirastu, N.; McDonnell, C.; Grzeszkowiak, E. J.; Mounier, N.; Imamura, F.; Merino, J.; Zheng, J.; Day, F. R.; Taba, N.; Concas, M. P.; Repetto, L.; Kentistou, K. A.; Robino, A.; Esko, T.; Joshi, P. K.; Fischer, K.; Ong, K. K.; Gaunt, T. R.; Kutalik, Z.; Perry, J.; Wilson, J. F.
10.1101/829952 — genetics — Posted on 2020-12-14
2312 The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research
Vandenabeele, M.; Veys, L.; Lemmens, S.; Hadoux, X.; Gelders, G.; Masin, L.; Serneels, L.; Theunis, J.; Saito, T.; Saido, T.; Jayapala, M.; De Boever, P.; De Strooper, B.; Stalmans, I.; van Wijngaarden, P.; Moons, L.; De Groef, L.
10.1101/2020.07.25.220707 — neuroscience — Posted on 2020-12-14
2313 Multi-contrast Anatomical Subcortical Structures Parcellation
Bazin, P.-L.; Alkemade, A.; Mulder, M.; Henry, A. G.; Forstmann, B.
10.1101/2020.05.26.115865 — neuroscience — Posted on 2020-12-14
2314 Crop-photoperiodism model 2.0 for the panicle-initiation date of sorghum and rice that includes daily changes in sunrise and sunset times
Clerget, B.; Sidibe, M.; Bueno, C. S.; Grenier, C.; Kawakata, T.; Domingo, A. J.; Layaoen, H. L.; Palacios, N. G.; Bernal, J. H.; Trouche, G.; Chantereau, J.
10.1101/2020.11.29.402628 — plant biology — Posted on 2020-12-14
2315 CRISPRIdentify: Identification of CRISPR arrays using machine learning approach
Mitrofanov, A.; Alkhnbashi, O. S.; Shmakov, S. A.; Makarova, K. S.; Koonin, E. V.; Backofen, R.
10.1101/2020.11.05.369512 — bioinformatics — Posted on 2020-12-14
2316 High affinity modified ACE2 receptors protect from SARS-CoV-2 infection in hamsters
Higuchi, Y.; Suzuki, T.; Arimori, T.; Ikemura, N.; Kirita, Y.; Ohgitani, E.; Mazda, O.; Motooka, D.; Nakamura, S.; Sakai, Y.; Itoh, Y.; Sugihara, F.; Matsuura, Y.; Matoba, S.; Okamoto, T.; Takagi, J.; Hoshino, A.
10.1101/2020.09.16.299891 — bioengineering — Posted on 2020-12-14
2317 Molnupiravir (EIDD-2801) inhibits SARS-CoV2 replication in Syrian hamsters model
Abdelnabi, R.; Foo, C. S.; Kaptein, S. J. F.; Zhang, X.; Langendries, L.; Vangeel, L.; Vergote, V.; Heylen, E.; Dallmeier, K.; Chatterjee, A. K.; De Jonghe, S.; Weynand, B.; Neyts, J.
10.1101/2020.12.10.419242 — microbiology — Posted on 2020-12-14
2318 A traditional medicine, Respiratory Detox Shot (RDS), inhibits the infection of SARS-CoV, SARS-CoV-2, and the Influenza A virus in vitro
Hetrick, B.; Yu, D.; Olanrewaju, A.; Chilin, L.; He, S.; Debbagh, D.; Ma, Y.-C.; Hofmann, L.; Hakami, R.; Wu, Y.
10.1101/2020.12.10.420489 — microbiology — Posted on 2020-12-14
2319 Retinoic Acid Inducible Gene-I like Receptors Activate Snail and Slug to Limit RNA Viral Infections
Vedagiri, D.; Gupta, D.; Mishra, A.; Krishna, G.; Bhaskar, M.; Basu, A.; Nayak, D.; Kalia, M.; Valiya, M. V.; Harshan, K. H.
10.1101/2020.10.27.357509 — immunology — Posted on 2020-12-14
2320 Extracellular Vesicles Analysis in the COVID-19 Era: Insights on Serum Inactivation Protocols Towards Downstream Isolation and Analysis
Frigerio, R.; Musico', A.; Brucale, M.; Ridolfi, A.; Galbiati, S.; Vago, R.; Bergamaschi, G.; Ferretti, A.; Chiari, M.; Valle, F.; Gori, A.; Cretich, M.
10.1101/2020.12.10.417758 — biochemistry — Posted on 2020-12-14
2322 Cell line-specific network models of ER+ breast cancer identify PI3Kα inhibitor sensitivity factors and drug combinations
Gomez Tejeda Zanudo, J.; Mao, P.; Alcon, C.; Kowalski, K. J.; Johnson, G. N.; Xu, G.; Baselga, J.; Scaltriti, M.; Letai, A.; Montero, J.; Albert, R.; Wagle, N.
10.1101/2020.08.25.261370 — cancer biology — Posted on 2020-12-13
2323 Characterization of Wnt Signaling Genes in Diaphorina citri, Asian citrus psyllid
Vosburg, C.; Reynolds, M.; Noel, R.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.09.21.306100 — genomics — Posted on 2020-12-13
2325 The role of mechanical interactions in EMT
Murphy, R. J.; Buenzli, P. R.; Tambyah, T. A.; Thompson, E. W.; Hugo, H. J.; Baker, R. E.; Simpson, M. J.
10.1101/2020.12.09.418434 — biophysics — Posted on 2020-12-13
2326 A New and Improved Genome Sequence of Cannabis sativa
Braich, S.; Baillie, R. C.; Spangenberg, G.; Cogan, N. O. I.
10.1101/2020.12.13.422592 — genomics — Posted on 2020-12-13
2328 Mechano-chemical feedback leads to competition for BMP signalling during pattern formation
Toddie-Moore, D.; Montanari, M.; Vi Tran, N.; Brik, E.; Antson, H.; Ciudad-Salazar, I.; Shimmi, O.
10.1101/2020.09.23.309435 — developmental biology — Posted on 2020-12-13
2330 Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice
Bennett, C.; Green, J.; Ciancio, M.; Goral, J.; Pitstick, L.; Pytynia, M.; Meyer, A.; Kwatra, N.; Jadavji, N. M.
10.1101/2020.12.13.422535 — neuroscience — Posted on 2020-12-13
2331 Ohm's Law for increasing fitness gene expression with selection pressure
Ciechonska, M.; Sturrock, M.; Grob, A.; Larrouy-Maumus, G.; Shahrezaei, V.; Isalan, M.
10.1101/693234 — systems biology — Posted on 2020-12-13
2332 Computable Early C. elegans Embryo with a Data-driven Phase Field Model
Kuang, X.; Guan, G.; Wong, M.-K.; Chan, L.-Y.; Zhao, Z.; Tang, C.; Zhang, L.
10.1101/2020.12.13.422560 — systems biology — Posted on 2020-12-13
2334 Surveying the contribution of rare variants to the genetic architecture of human disease through exome sequencing of 177,882 UK Biobank participants
Wang, Q.; Dhindsa, R. S.; Carss, K.; Harper, A. R.; Nag, A.; Tachmazidou, I.; Vitsios, D.; Deevi, S. V.; Mackay, A.; Muthas, D.; Hühn, M.; Monkley, S.; Olsson, H.; Wasilewski, S.; Smith, K. R.; March, R.; Platt, A.; Haefliger, C.; AstraZeneca Genomics Initiative, ; Petrovski, S.
10.1101/2020.12.13.422582 — genomics — Posted on 2020-12-13
2335 Association of Structural Variation with Cardiometabolic Traits in Finns
Chen, L.; Abel, H. J.; Das, I.; Larson, D. E.; Ganel, L.; Kanchi, K. L.; Regier, A. A.; Young, E. P.; Kang, C. J.; Scott, A. J.; Chiang, C.; Wang, X.; Lu, S.; Christ, R.; Service, S.; Chiang, C. W. K.; Havulinna, A. S.; Kuusisto, J.; Boehnke, M. W. K.; Laakso, M.; Palotie, A.; Ripatti, S.; Freimer, N. B.; Locke, A. E.; Stitziel, N. O.; Hall, I. M.
10.1101/2020.12.13.422502 — genetics — Posted on 2020-12-13
2340 Computable Early C. elegans Embryo with a Data-driven Phase Field Model
Kuang, X.; Guan, G.; Wong, M.-K.; Chan, L.-Y.; Zhao, Z.; Tang, C.; Zhang, L.
10.1101/2020.12.13.422560 — systems biology — Posted on 2020-12-13
2342 Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine
Wen, J.; Padilla Mercado, G.; Volland, A.; Doden, H. L.; Lickwar, C. R.; Crooks, T.; Kakiyama, G.; Kelly, C.; Cocchiaro, J. L.; Ridlon, J. M.; Rawls, J. F.
10.1101/2020.12.13.422569 — physiology — Posted on 2020-12-13
2345 TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in in vitro models
Longo, M.; Meroni, M.; Erconi, V.; Carli, F.; Macchi, C.; Fortunato, F.; Ronchi, D.; Sabatini, S.; Paolini, E.; De Caro, E. R.; Alisi, A.; Miele, L.; Soardo, G.; Comi, G. P.; Valenti, L.; Ruscica, M.; Fracanzani, A. L. L.; Gastaldelli, A.; Dongiovanni, P.
10.1101/2020.12.13.422549 — genetics — Posted on 2020-12-13
2346 Translational control as a novel regulator of gradient sensing and chemotropism in yeast
Gelin-Licht, R.; Conlon, P. J.; Singh, R.; Baez, C.; Gal, L.; Schuldiner, M.; Levchenko, A.; Gerst, J. E.
10.1101/2020.12.13.422562 — cell biology — Posted on 2020-12-13
2348 Distributional changes in myelin-specific MRI markers uncover dynamics in the fornix following spatial navigation training
Anaby, D.; Tendler, B. C.; Treder, M. S.; Hametner, S.; Koeck, U.; Tax, C. M. W.; Parker, G. D.; Barazany, D.; Assaf, Y.; Jones, D. K.
10.1101/2020.12.13.422557 — neuroscience — Posted on 2020-12-13
2352 Exposure of mammary cells to lipid activates gene expression changes associated with ER-negative breast cancer via chromatin remodeling.
Yadav, S.; Virk, R.; Chung, C.; Van Derway, D.; Chen, D.; Burdett, K.; Gao, H.; Zeng, Z.; Ranjan, M.; Cottone, G.; Xuei, X.; Chandrasekaran, S.; Backman, V.; Chaterton, R.; Khan, S.; Clare, S.
10.1101/2020.12.13.422540 — cancer biology — Posted on 2020-12-13
2353 Regulatory elements can be essential for maintaining broad chromatin organization and cell viability
Liu, Y.; Ding, B.; Zheng, L.; Xu, P.; Liu, Z.; Chen, Z.; Wu, P.; Zhao, Y.; Pan, Q.; Guo, Y.; Wang, W.; Wei, W.
10.1101/2020.12.13.422554 — bioinformatics — Posted on 2020-12-13
2355 Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor
Islam, S. M. A.; Wu, Y.; Diaz-Gay, M.; Bergstrom, E. N.; He, Y.; Barnes, M.; Vella, M.; Wang, J.; Teague, J. W.; Clapham, P.; Moody, S.; Senkin, S.; Li, Y. R.; Riva, L.; Zhang, T.; Gruber, A. J.; Vangara, R.; Steele, C. D.; Otlu, B.; Khandekar, A.; Abbasi, A.; Humphreys, L.; Syulyukina, N.; Brady, S. W.; Alexandrov, B. S.; Pillay, N.; Zhang, J.; Adams, D. J.; Marticorena, I.; Wedge, D. C.; Landi, M. T.; Brennan, P.; Stratton, M. R.; Rozen, S. G.; Alexandrov, L. B.
10.1101/2020.12.13.422570 — bioinformatics — Posted on 2020-12-13
2358 Efficient Inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc
Wang, S.-S.; del Solar, V.; Yu, X.; Antonopoulos, A.; Friedman, A. E.; Agarwal, K.; Garg, M.; Ahmed, S. M.; Addya, A.; Nasirikenari, M.; Lau, J. T.; Dell, A.; Haslam, S. M.; Sampathkumar, S.-G.; Neelamegham, S.
10.1101/2020.12.13.422539 — biochemistry — Posted on 2020-12-13
2362 Identification of four linear B-cell epitopes on the SARS-CoV-2 spike protein able to elicit neutralizing antibodies
Li, L.; Zhao, Z.; Yang, X.; Li, W.; Chen, S.; Sun, T.; Wang, L.; He, Y.; Liu, G.; Han, X.; Wen, H.; Liu, Y.; Chen, Y.; Wang, H.; Li, J.; Su, Z.; Chen, D.; Wang, Y.; Li, X.; Yang, Z.; Wang, J.; Li, M.; Wang, T.; Wang, Y.; Fan, Y.; Wang, H.; Zhang, J.
10.1101/2020.12.13.422550 — microbiology — Posted on 2020-12-13
2363 From plants to ants: Fungal modification of leaf lipids for nutrition and communication in the leaf-cutter ant fungal garden ecosystem
Khadempour, L.; Kyle, J. E.; Webb-Robertson, B.-J. M.; Nicora, C. D.; Smith, F. B.; Smith, R. D.; Lipton, M. S.; Currie, C. R.; Baker, E. S.; Burnum-Johnson, K. E.
10.1101/2020.07.28.224139 — systems biology — Posted on 2020-12-13
2364 SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
Zhang, L.; Richards, A.; Khalil, A.; Wogram, E.; Ma, H.; Young, R. A.; Jaenisch, R.
10.1101/2020.12.12.422516 — genomics — Posted on 2020-12-13
2365 Lineage-specific control of convergent differentiation by a Forkhead repressor
Mizeracka, K.; Rogers, J. M.; Rumley, J. D.; Shaham, S.; Bulyk, M. L.; Murray, J. I.; Heiman, M. G.
10.1101/758508 — developmental biology — Posted on 2020-12-13
2367 A novel cell culture system modeling the SARS-CoV-2 life cycle
Ju, X.; Zhu, Y.; Wang, Y.; Li, J.; Zhang, J.; Gong, M.; Ren, W.; Li, S.; Zhong, J.; Zhang, Q. C.; Zhang, R.; Ding, Q.
10.1101/2020.12.13.422469 — microbiology — Posted on 2020-12-13
2368 Evaluation of in vitro activity of copper gluconate against SARS-CoV-2 using confocal microscopy-based high content screening
Rodriguez, K.; Rigaill, J.; Audoux, E.; Saunier, F.; Botelho-Nevers, E.; Prier, A.; Dickerscheit, Y.; Pillet, S.; Pozzetto, B.; Bourlet, T.; Verhoeven, P. O.
10.1101/2020.12.13.422548 — microbiology — Posted on 2020-12-13
2369 Generation of a SARS-CoV-2 Replicon as a Model System to Dissect Virus Replication and Antiviral Inhibition
He, X.; Quan, S.; Xu, M.; Rodriguez, S.; Goh, S. L.; Wei, J.; Fridman, A.; Koeplinger, K. A.; Carroll, S. S.; Grobler, J. A.; Espeseth, A. S.; Olsen, D. B.; Hazuda, D. J.; Wang, D.
10.1101/2020.12.12.422532 — microbiology — Posted on 2020-12-13
2372 Revisiting the Out of Africa event with a novel Deep Learning approach
Montinaro, F.; Pankratov, V.; Yelmen, B.; Pagani, L.; Mondal, M.
10.1101/2020.12.10.419069 — genetics — Posted on 2020-12-13
2373 The Allen Cell and Structure Segmenter: a new open source toolkit for segmenting 3D intracellular structures in fluorescence microscopy images
Chen, J.; Ding, L.; Viana, M. P.; Lee, H.; Sluezwski, M. F.; Morris, B.; Hendershott, M. C.; Yang, R.; Mueller, I. A.; Rafelski, S. M.
10.1101/491035 — cell biology — Posted on 2020-12-13
2376 Adaptive current-flow models of ECT: Explaining individual static impedance, dynamic impedance, and brain current delivery
Unal, G.; Swami, J. K.; Canela, C.; Cohen, S.; Khadka, N.; Rad, M.; Short, B.; Argyelan, M.; Sackeim, H.; Bikson, M.
10.1101/2020.11.08.373712 — bioengineering — Posted on 2020-12-13
2378 Influence of membrane-cortex linkers on the extrusion of membrane tubes
Paraschiv, A.; Lagny, T.; Coudrier, E.; Vanhille Campos, C.; Bassereau, P.; Saric, A.
10.1101/2020.07.28.224741 — biophysics — Posted on 2020-12-13
2379 A dynamic, spatially periodic, micro-pattern of HES5 underlies neurogenesis in the mouse spinal cord.
Biga, V.; Hawley, J. J.; Soto, X.; Johns, E.; Han, D.; Bennett, H.; Adamson, A. D.; Kursawe, J.; Glendinning, P.; Manning, C. S.; Papalopulu, N.
10.1101/2020.08.03.234369 — developmental biology — Posted on 2020-12-13
2382 Temporal dynamics of animacy categorization in the brain of patients with mild cognitive impairment
Karimi, H.; Marefat, H.; Khanbagi, M.; Kalafatis, C.; Modarres, M. H.; Vahabi, Z.; Khaligh-Razavi, S.-M.
10.1101/2020.11.20.390435 — neuroscience — Posted on 2020-12-13
2383 Autophagy is required for lipid homeostasis during dark-induced senescence in Arabidopsis
Barros, J. A.; Magen, S.; Lapidot-Cohen, T.; Rosental, L.; Brotman, Y.; Araujo, W. L.; Avin-Wittenberg, T.
10.1101/2020.08.10.245092 — plant biology — Posted on 2020-12-13
2385 Isoform-specific regulation of rhythmic gene expression by alternative polyadenylation
Greenwell, B. J.; Beytebiere, J. R.; Lamb, T. M.; Bell-Pedersen, D.; Merlin, C.; Menet, J. S.
10.1101/2020.12.12.422514 — molecular biology — Posted on 2020-12-13
2386 Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p
Dietrich, M. H.; Chan, L.-J.; Adair, A.; Keremane, S.; Pymm, P.; Lo, A. W.; Cao, Y.-C.; Tham, W.-H.
10.1101/2020.12.12.422521 — microbiology — Posted on 2020-12-13
2387 Characterization of cyanobacteria isolated from thermal muds of Balaruc-Les-Bains (France) and description of a new genus and species Pseudochroococcuscouteii
Duval, C.; Hamlaoui, S.; Piquet, B.; Toutirais, G.; Yepremian, C.; Reinhart, A.; Duperron, S.; MARIE, B.; Demay, J.; Bernard, C.
10.1101/2020.12.12.422513 — microbiology — Posted on 2020-12-13
2388 Enhanced reflexive eye closure is mediated by ipRGC signals and is specific to migraine with visual aura
Kaiser, E. A.; McAdams, H.; Igdalova, A.; Haggerty, E. B.; Cucchiara, B.; Brainard, D. H.; Aguirre, G. K.
10.1101/2020.12.12.422528 — neuroscience — Posted on 2020-12-13
2389 Comprehensive quantitative proteome analysis of Aedes aegypti identifies proteins and pathways involved in Wolbachia pipientis and Zika virus interference phenomenon
Martins, M.; Ramos, L. F. C.; Murillo, J. E. R.; Torres, A.; de Carvalho, S. S.; Domont, G. B.; de Oliveira, D. M. P.; Mesquita, R. D.; Nogueira, F. C. S.; Maciel-de-Freitas, R.; Junqueira, M.
10.1101/2020.12.12.422506 — biochemistry — Posted on 2020-12-13
2391 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, L. D.; Li, W.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2020-12-12
2392 Genetic Determinants of Wheat Resistance to Common Root Rot (Spot Blotch), Fusarium Crown Rot, and Sharp Eyespot
Su, J.; Zhao, J.; Zhao, S.; Li, M.; Shang, X.; Pang, S.; Chen, S.; Chen, F.; Zhen, W.; Kang, Z.; Wang, X.
10.1101/2020.07.30.228932 — genetics — Posted on 2020-12-12
2395 Olfactory memory consolidation requires the TRPV channel OSM-9 in sensory neurons of the circuit.
Benedetti, K. L.; Saifuddin, F. A.; Miller, J. M.; Chandra, R.; Chen, A.; Dunn, R. L.; Kaye, J. A.; Zhang, B.; Kato, S.; Gallegos, M. E.; L'Etoile, N.
10.1101/2020.11.27.400747 — neuroscience — Posted on 2020-12-12
2396 Lkb1 is a master regulator of VSMC fate and function in mice
Cai, Z.; Song, P.; You, S.; Liu, Z.; Zhao, F.; Mu, J.; Zheng, X.; Ding, Y.; Xiao, L.; Ramprasath, T.; Qiu, Y.; He, B.; Zou, M.-H.
10.1101/2020.12.12.422410 — physiology — Posted on 2020-12-12
2397 Barnacle-Inspired Paste for Instant Hemostatic Tissue Sealing
Yuk, H.; Wu, J.; Mao, X.; Varela, C. E.; Roche, E. T.; Nabzdyk, C. S.; Zhao, X.
10.1101/2020.12.12.422505 — bioengineering — Posted on 2020-12-12
2398 Pioneer activity of an oncogenic fusion transcription factor at inaccessible chromatin
Sunkel, B.; Wang, M.; LaHaye, S.; Kelly, B. J.; Fitch, J. R.; Barr, F. G.; White, P.; Stanton, B. Z.
10.1101/2020.12.11.420232 — genomics — Posted on 2020-12-12
2400 BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ
Jeong, J.; Kang, K.; Jo, D. S.; Cong, A. T.; Kim, D.; Cho, D.-H.; Schellenberg, M. J.; Calderwood, S. K.; Chen, B. P. C.; Bunch, H.
10.1101/2020.12.12.422337 — molecular biology — Posted on 2020-12-12
2402 Multidisciplinary Interrogation of a Crucial Protein Interface in the Type II Secretion System
Escobar, C. A.; Douzi, B.; Ball, G.; Barbat, B.; Alphonse, S.; Quinton, L.; Vouhoux, R.; Forest, K. T.
10.1101/2020.12.11.420943 — microbiology — Posted on 2020-12-12
2405 Physiological and transcriptomic response of Medicago truncatula to high and low benefit mycorrhizal fungi
Cope, K. R.; Kafle, A.; Yakha, J. K.; Pfeffer, P. E.; Strahan, G. D.; Garcia, K.; Subramanian, S.; Bücking, H.
10.1101/2020.12.11.421693 — plant biology — Posted on 2020-12-12
2407 Human liver microbiota modeling strategy at the early onset of fibrosis
Burcelin, R.; Champion, C.; Neagoe, R. M.; Effernberger, M.; Sala, D. T.; Servant, F.; Christensen, J. E.; Arnoriaga-Rodriguez, M.; Amar, J.; Lelouvier, B.; Gamboa, F.; Tilg, H.; Federici, M.; Fernandez-Real, J. M.; Loubes, J.-M.
10.1101/2020.12.10.419051 — pathology — Posted on 2020-12-12
2408 Choice of fluorophore affects dynamic DNA nanostructures
Jahnke, K.; Grubmüller, H.; Igaev, M.; Göpfrich, K.
10.1101/2020.12.12.422444 — biophysics — Posted on 2020-12-12
2410 The molecular basis, genetic control and pleiotropic effects of local gene co-expression
Ribeiro, D. M.; Rubinacci, S.; Ramisch, A.; Hofmeister, R. J.; Dermitzakis, E. T.; Delaneau, O.
10.1101/2020.12.11.421396 — genomics — Posted on 2020-12-12
2411 The genomic epidemiology of multi-drug resistant nontyphoidal Salmonella causing invasive disease in sub-Saharan Africa
Park, S. E.; Pham, D. T.; Pak, G. D.; Panzner, U.; Espinoza, L. M. C.; von Kalckreuth, V.; Im, J.; Mogeni, O. D.; Schutt-Gerowitt, H.; Crump, J. A.; BREIMAN, R. F.; Abu-Sarkodie, Y.; Owusu-Dabo, E.; Rakotozandrindrainy, R.; Soura, A. B.; Aseffa, A.; Gasmelseed, N.; Sooka, A.; Keddy, K. H.; May, J.; Aaby, P.; Biggs, H. M.; Hertz, J. T.; Montgomery, J. M.; Cosmas, L.; Olack, B.; Fields, B.; Sarpong, N.; Razafindrabe, T. J. L.; Raminosoa, T. M.; Kabore, L. P.; Sampo, E.; Teferi, M.; Yeshitela, B.; Tayeb, M. A. E.; Krumkamp, R.; Dekker, D. M.; Jaeger, A.; Tall, A.; Niang, A.; Bjerregaard-Andersen,
10.1101/2020.12.11.422246 — genomics — Posted on 2020-12-12
2412 Mosaic antimicrobial resistance/virulence plasmid in hypervirulent ST2096 Klebsiella pneumoniae in India: The rise of a new superbug?
Shankar, C.; Vasudevan, K.; Jacob, J. J.; Baker, S.; Isaac, B. J.; Neeravi, A. R.; Muthuirulandi Sethuvel, D. P.; George, B.; Veeraraghavan, B.
10.1101/2020.12.11.422261 — genomics — Posted on 2020-12-12
2415 Linking functional traits with tree growth and forest productivity in Quercus ilex forests along a climatic gradient
Salazar Zarzosa, P. C.; Diaz, A.; Olmo, M.; Ruiz-Benito, P.; Barron, V.; Bastias, C. C.; Garcia de la Riva, E.; Villar, R.
10.1101/2020.12.12.422386 — ecology — Posted on 2020-12-12
2418 An In Vivo Method for Diversifying the Functions of Therapeutic Antibodies
Tian, M.; Cheng, H.-L.; Kimble, M. T.; McGovern, K.; Waddicor, P.; Chen, Y.; Cantor, E.; Qiu, M.; Tuchel, M.-E.; Dao, M.; Alt, F. W.
10.1101/2020.12.12.421834 — immunology — Posted on 2020-12-12
2420 Widespread decrease of cerebral vimentin-immunoreactive astrocytes in depressed suicides
O'Leary, L.; Belliveau, C.; Davoli, M. A.; Ma, J. C.; Tanti, A.; Turecki, G.; Mechawar, N.
10.1101/2020.12.12.422510 — neuroscience — Posted on 2020-12-12
2421 Annexin A1 tripeptide mimetic increases sirtuin-3 to augment mitochondrial function and limit ischemic kidney injury
Suliman, H.; Ma, Q.; Zhang, Z.; Ren, J.; Morris, B. T.; Crowley, S. D.; Ulloa, L.; Privratsky, J.
10.1101/2020.12.11.421859 — physiology — Posted on 2020-12-12
2426 Epilepsy kinase CDKL5 is a DNA damage sensor which controls transcriptional activity at DNA breaks
Khanam, T.; Munoz, I.; Weiland, F.; Carroll, T.; Borsos, B. N.; Pantazi, V.; Slean, M.; Novak, M.; Toth, R.; Appleton, P.; Pankotai, T.; Zhou, H.; Rouse, J.
10.1101/2020.12.10.419747 — cell biology — Posted on 2020-12-12
2427 Bridges, not walls: the hippocampus builds narrative memories across distant events
Cohn-Sheehy, B. I.; Delarazan, A. I.; Reagh, Z. M.; Crivelli-Decker, J. E.; Zacks, J. M.; Ranganath, C.
10.1101/2020.12.11.422162 — neuroscience — Posted on 2020-12-12
2429 Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy
Summers, P. A.; Lewis, B.; Gonzalez-Garcia, J.; Porreca, R. M.; Lim, A. H. M.; Cadinu, P.; Martin-Pintado, N.; Mann, D.; Edel, J. B.; Vannier, J.-B.; Kuimova, M.; Vilar, R.
10.1101/2020.04.01.019794 — biophysics — Posted on 2020-12-12
2433 Chronic deep brain stimulation of the human nucleus accumbens region disrupts the stability of inter-temporal preferences.
Wagner, B. J.; Schueller, C. B.; Schueller, T.; Baldermann, J. C.; Kohl, S.; Visser-Vandewalle, V.; Huys, D.; Kuhn, J.; Peters, J.
10.1101/2020.12.11.417337 — neuroscience — Posted on 2020-12-12
2436 Individual differences in honey bee behavior enabled by plasticity in brain gene regulatory networks
Jones, B. M.; Rao, V. D.; Gernat, T.; Jagla, T.; Cash-Ahmed, A.; Rubin, B. E.; Comi, T. J.; Bhogale, S.; Husain, S. S.; Blatti, C.; Middendorf, M.; Sinha, S.; Chandrasekaran, S.; Robinson, G. E.
10.1101/2020.09.09.289272 — genomics — Posted on 2020-12-12
2437 Precision methylome and in vivo methylation kinetics characterization of Klebsiella pneumoniae
Fu, J.; Zhang, J.; Yang, L.; Ding, N.; Yue, L.; Zhang, X.; Lu, D.; Jia, X.; Li, C.; Guo, C.; Yin, Z.; Jiang, X.; Zhao, Y.; Chen, F.; Zhou, D.
10.1101/2020.12.04.409839 — genomics — Posted on 2020-12-12
2438 AKAP350 REGULATES CYTOSKELETON REMODELING AND LFA-1 ORGANIZATION DURING NK CYTOLYTIC RESPONSE
Pariani, A. P.; Almada, E.; Hidalgo, F.; Borini-Etichetti, C.; Vena, R.; Favre, C.; Goldenring, J. R.; Larocca, M. C.
10.1101/2020.10.27.357970 — cell biology — Posted on 2020-12-12
2443 Optimized gene expression from bacterial chromosome by high-throughput integration and screening
Saleski, T. E.; Chung, M. T.; Carruthers, D. N.; Khasbaatar, A.; Kurabayashi, K.; Lin, X.
10.1101/2020.07.29.226290 — synthetic biology — Posted on 2020-12-12
2445 Cell type-specific isolation and transcriptomic profiling informs glial pathology in human temporal lobe epilepsy
Tome-Garcia, J.; Nudelman, G.; Mussa, Z.; Caballero, E.; Jiang, Y.; Beaumont, K. G.; Wang, Y.-C.; Sebra, R. G.; Akbarian, S.; Pinto, D.; Zaslavsky, E.; Tsankova, N. M.
10.1101/2020.12.11.421370 — neuroscience — Posted on 2020-12-12
2447 Osteoprotegerin expression in liver is induced by IL-13 through TGF-β
Adhyatmika, A.; Putri, K. S.; Gore, E.; Mangnus, K.; Reker-Smit, C.; Schuppan, D.; Beljaars, L.; Olinga, P.; Melgert, B. N.
10.1101/2020.12.11.421479 — pathology — Posted on 2020-12-12
2448 Unbiased integration of single cell multi-omics data
DOU, J.; Liang, S.; Mohanty, V.; Cheng, X.; Kim, S.; Choi, J.; Li, Y.; Rezvani, K.; Chen, R.; Chen, K.
10.1101/2020.12.11.422014 — bioinformatics — Posted on 2020-12-11
2454 Introducing selfisher: open source software for statistical analyses of fishing gear selectivity
Brooks, M. E.; Melli, V.; Savina, E.; Santos, J.; Millar, R.; O'Neill, F. G.; Veiga Malta, T. A. M. d.; Krag, L. A.; Feekings, J. P.
10.1101/2020.12.11.421362 — ecology — Posted on 2020-12-12
2455 A viral histone-like protein exploits H1-HMGB1 antagonism for chromatin invasion
Lynch, K. L.; Bat-Erdene, M.; Dillon, M. R.; Lewis, H. C.; Avgousti, D. C.
10.1101/2020.12.11.418129 — microbiology — Posted on 2020-12-11
2457 Kaposi's Sarcoma Herpesvirus Is Associated with Osteosarcoma in Xinjiang Uyghur Population
Chen, Q.; Chen, J.; Li, Y.; Liu, D.; Zeng, Y.; Tian, Z.; Yunus, A.; Yang, Y.; Lu, J.; Song, X.; Yuan, Y.
10.1101/2020.12.11.421719 — microbiology — Posted on 2020-12-11
2458 TCRMatch: Predicting T-cell receptor specificity based on sequence similarity to previously characterized receptors
Chronister, W. D.; Crinklaw, A.; Mahajan, S.; Vita, R.; Kosaloglu-Yalcin, Z.; Yan, Z.; Greenbaum, J. A.; Jessen, L. E.; Nielsen, M.; Christley, S.; Cowell, L. G.; Sette, A.; Peters, B.
10.1101/2020.12.11.418426 — immunology — Posted on 2020-12-11
2459 Rapid encoding of temporal sequences discovered in brain dynamics
Bonetti, L.; Brattico, E.; Carlomagno, F.; Donati, G.; Cabral, J.; Haumann, N. T.; Deco, G.; Vuust, P.; Kringelbach, M. L.
10.1101/2020.12.11.421669 — neuroscience — Posted on 2020-12-11
2461 Effects of beta- and gamma-band rhythmic stimulation on motor inhibition
Leunissen, I.; Van Steenkiste, M.; Heise, K.; Santos Monteiro, T.; Dunovan, K.; Mantini, D.; Coxon, J. P.; Swinnen, S. P.
10.1101/2020.12.11.422006 — neuroscience — Posted on 2020-12-11
2462 Four-dimensional tractography animates neural propagations via distinct interhemispheric pathways
Mitsuhashi, T.; Sonoda, M.; Jeong, J.-w.; Silverstein, B. H.; Iwaki, H.; Luat, A. F.; Sood, S.; Asano, E.
10.1101/2020.12.11.421495 — neuroscience — Posted on 2020-12-12
2463 Effects of early life adversity on maternal effort and glucocorticoids in wild olive baboons
Patterson, S. K.; Hinde, K.; Bond, A. B.; Trumble, B. C.; Strum, S. C.; Silk, J. B.
10.1101/2020.12.11.418095 — zoology — Posted on 2020-12-11
2467 An Extensive Sequence Dataset of Gold-Standard Samples for Benchmarking and Development
Baid, G.; Nattestad, M.; Kolesnikov, A.; Goel, S.; Yang, H.; Chang, P.-C.; Carroll, A.
10.1101/2020.12.11.422022 — genomics — Posted on 2020-12-11
2470 Ancient DNA Analysis of Archaeological Specimens Extends Chinook Salmons Known Historic Range to San Francisco Bay and Its Southernmost Watershed
Lanman, R. B.; Hylkema, L.; Boone, C. M.; Allee, B.; Castillo, R. O.; Moreno, S. A.; Flores, M. F.; Desilva, U.; Bingham, B.; Kemp, B. M.
10.1101/2020.12.11.421065 — ecology — Posted on 2020-12-11
2474 The hidden pangenome: comparative genomics reveals pervasive diversity in symbiotic and free-living sulfur-oxidizing bacteria
Ansorge, R.; Romano, S.; Sayavedra, L.; Rubin-Blum, M.; Gruber-Vodicka, H. R.; Scilipoti, S.; Molari, M.; Dubilier, N.; Petersen, J.
10.1101/2020.12.11.421487 — microbiology — Posted on 2020-12-11
2476 Basal G-protein-gated inwardly rectifying potassium (Kir3/GirK) channels activity governs synaptic plasticity that supports dorsal hippocampus-dependent cognitive functions
Temprano-Carazo, S.; Djebari, S.; Iborra-Lazaro, G.; Sanchez-Rodriguez, I.; Nava-Mesa, M. O.; Munera, A.; Gruart, A.; Delgado-Garcia, J. M.; Jimenez-Diaz, L.; Navarro-Lopez, J. D.
10.1101/2020.12.11.421735 — neuroscience — Posted on 2020-12-11
2477 Hippocampal cells multiplex positive and negative engrams
Shpokayte, M.; McKissick, O.; Yuan, B.; Rahsepar, B.; Fernandez, F. R.; Ruesch, E. A.; Grella, S. L.; White, J. A.; Liu, X. S.; Ramirez, S.
10.1101/2020.12.11.419887 — neuroscience — Posted on 2020-12-11
2479 A Synthetic Transcription Platform for Programmable Gene Expression in Mammalian Cells
Chen, W. C. W.; Gaidukov, L.; Wu, M.-R.; Cao, J.; Choi, G. C. G.; Utomo, R. P.; Chen, Y.-C.; Wroblewska, L.; Zhang, L.; Weiss, R.; Lu, T. K.
10.1101/2020.12.11.420000 — synthetic biology — Posted on 2020-12-11
2480 Analysis of the area and the number of pulmonary alveoli through the normal aging process in CD1 mouse
Ortega-Martinez, M.; Gutierrez-Arenas, E.; Gutierrez-Davila, V.; Niderhauser-Garcia, A.; Cerda-Flores, R. M.; Jaramillo-Rangel, G.
10.1101/2020.12.11.421032 — pathology — Posted on 2020-12-11
2483 Multithreaded variant calling in elPrep 5
Herzeel, C.; Costanza, P.; Decap, D.; Fostier, J.; Wuyts, R.; Verachtert, W.
10.1101/2020.12.11.421073 — bioinformatics — Posted on 2020-12-11
2485 Oligonucleotide Capture Sequencing of the SARS-CoV-2 Genome and Subgenomic Fragments from COVID-19 Individuals
doddapaneni, h.; Cregeen, S. J.; Sucgang, R.; Meng, Q.; Qin, X.; Avadhanula, V.; Chao, H.; Menon, V.; Nicholson, E.; Henke, D.; Piedra, F.-A.; Rajan, A.; Momin, Z.; Kottapalli, K.; Hoffman, K. L.; Sedlazeck, F. J.; Metcalf, G.; Piedra, P. A.; Muzny, D. M.; Petrosino, J. F.; Gibbs, R. A.
10.1101/2020.12.11.421057 — genomics — Posted on 2020-12-11
2486 Morphological and genomic shifts in mole-rat 'queens' increase fecundity but reduce skeletal integrity
Johnston, R. A.; Vullioud, P.; Thorley, J.; Kirveslahti, H.; Shen, L.; Mukherjee, S.; Karner, C.; Clutton-Brock, T.; Tung, J.
10.1101/2020.07.31.231266 — evolutionary biology — Posted on 2020-12-11
2488 MogR is a ubiquitous transcriptional repressor affecting motility, biofilm formation and virulence in Bacillus thuringiensis
Smith, V.; Josefsen, M.; Lindbäck, T.; Hegna, I. K.; Finke, S.; Tourasse, N. J.; Nielsen-LeRoux, C.; Okstad, O. A.; Fagerlund, A.
10.1101/2020.09.26.311894 — microbiology — Posted on 2020-12-11
2493 BitEpi: A Fast and Accurate Exhaustive Higher-Order Epistasis Search
Bayat, A.; Hosking, B.; Jain, Y.; Hosking, C.; Kodikara, M.; Reti, D.; Twine, N.; C. Bauer, D.
10.1101/858282 — bioinformatics — Posted on 2020-12-11
2498 Spatial population genomics of a recent mosquito invasion
Schmidt, T. L.; Swan, T.; Chung, J.; Karl, S.; Demok, S.; Yang, Q.; Field, M. A.; Muzari, M. O.; Ehlers, G.; Brugh, M.; Bellwood, R.; Horne, P.; Burkot, T. R.; Ritchie, S.; Hoffmann, A. A.
10.1101/2020.11.30.405191 — genomics — Posted on 2020-12-11
2499 Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis
Shkoporov, A. N.; Khokhlova, E. V.; Stephens, N.; Hueston, C.; Seymour, S.; Hryckowian, A. J.; Scholz, D.; Ross, R. P.; Hill, C.
10.1101/2020.12.02.408625 — microbiology — Posted on 2020-12-11
2501 A competition of critics in human decision-making
Enkhtaivan, E.; Nishimura, J.; Ly, C.; Cochran, A. L.
10.1101/2020.12.01.407239 — neuroscience — Posted on 2020-12-11
2502 Leukodystrophy resembling Vanishing White Matter Disease is recapitulated by brain-specific depletion of apoptosis regulator MCL-1
Cleveland, A. H.; Romero, A.; Alfonso Azcona, L.; Herrero, M.; Nikolova, V. D.; Moy, S.; Elroy-Stein, O.; Gama, V.; Gershon, T. R.
10.1101/2020.12.02.408138 — neuroscience — Posted on 2020-12-11
2503 Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioural, and transcriptional study
Guma, E.; Bordignon, P.; Devenyi, G. A.; Gallino, D.; Anastassiadis, C.; Cvetkovska, V.; Barry, A. D.; Snook, E.; Germann, J.; Greenwood, C. M. T.; Misic, B.; Bagot, R. C.; Chakravarty, M. M.
10.1101/2020.12.03.406454 — neuroscience — Posted on 2020-12-11
2504 Brainrender: a python-based software for visualizinganatomically registered data
Claudi, F.; Tyson, A. L.; Petrucco, L.; Margrie, T. W.; Portugues, R.; Branco, T.
10.1101/2020.02.23.961748 — neuroscience — Posted on 2020-12-11
2505 Physiological and pathological changes in the enteric nervous system of rotenone-exposed mice as potential early biomarkers for Parkinson's disease
Schaffernicht, G.; Shang, Q.; Stievenard, A.; Bötzel, K.; Dening, Y.; Kempe, R.; Toussaint, M.; Gündel, D.; Kranz, M.; Reichmann, H.; Vanbesien-Mailliot, C.; Brust, P.; Dieterich, M.; Funk, R. H. W.; Ravens, U.; Pan-Montojo, F. J.
10.1101/2020.12.11.421164 — neuroscience — Posted on 2020-12-11
2506 The acute effects of cannabidiol on emotional processing and anxiety: a neurocognitive imaging study
Bloomfield, M. A.; Yamamori, Y.; Hindocha, C.; Jones, A. P.; Yim, J. L.; Walker, H. R.; Statton, B.; Wall, M. B.; Lees, R. H.; Howes, O. D.; Curran, V. H.; Roiser, J. P.; Freeman, T. P.
10.1101/2020.12.11.421776 — neuroscience — Posted on 2020-12-11
2508 Heat Stress Interferes with Formation of Double-Strand Breaks and Homolog Synapsis in Arabidopsis thaliana
Ning, Y.; Liu, Q.; Wang, C.; Qin, E.; Wu, Z.; Wang, M.; Yang, K.; Elesawi, I. E.; Chen, C.; Liu, H.; Qin, R.; Liu, B.
10.1101/2020.10.02.324269 — plant biology — Posted on 2020-12-11
2509 SPEAQeasy: a Scalable Pipeline for Expression Analysis and Quantification for R/Bioconductor-powered RNA-seq analyses
Eagles, N. J.; Burke, E. E.; Leonard, J.; Barry, B. K.; Stolz, J. M.; Huuki, L.; Phan, B. N.; Larrios Serrato, V.; Gutierrez-Millan, E.; Aguilar-Ordonez, I.; Jaffe, A. E.; Collado-Torres, L.
10.1101/2020.12.11.386789 — bioinformatics — Posted on 2020-12-11
2510 BBrowser: Making single-cell data easily accessible
Le, T.; Phan, T.; Pham, M.; Tran, D.; Lam, L.; Nguyen, T.; Truong, T.; Vuong, H.; Luu, T.; Phung, N.; Nguyen, T.; Pham, O.; Nguyen, A.; Nguyen, H.; Tran, H.; Tran, L.; Nguyen, H. A.; Tran, T.; Nguyen, N.; Tran, N.; Boysen, C.; Nguyen, U.; Pham, V.; Theodore, K.; Pham, N.; Gill, T.; Pham, S.
10.1101/2020.12.11.414136 — bioinformatics — Posted on 2020-12-11
2512 Shifts from pulled to pushed range expansions caused by reduction of landscape connectivity
Dahirel, M.; Bertin, A.; Haond, M.; Blin, A.; Lombaert, E.; Calcagno, V.; Fellous, S.; Mailleret, L.; Malausa, T.; Vercken, E.
10.1101/2020.05.13.092775 — ecology — Posted on 2020-12-11
2523 Systematic characterization of gene function in a photosynthetic organism
Vilarrasa-Blasi, J.; Fauser, F.; Onishi, M.; Ramundo, S.; Patena, W.; Millican, M.; Osaki, J.; Philp, C.; Nemeth, M.; Salome, P. A.; Li, X.; Wakao, S.; Kim, R. G.; Kaye, Y.; Grossman, A. R.; Niyogi, K. K.; Merchant, S.; Cutler, S.; Walter, P.; Dinneny, J. R.; Jonikas, M. C.; Jinkerson, R. E.
10.1101/2020.12.11.420950 — systems biology — Posted on 2020-12-11
2525 The transcriptomic landscapes of diverse rice cultivars grown under mild drought conditions
Kawakatsu, T.; Teramoto, S.; Takayasu, S.; Maruyama, N.; Nishijima, R.; Kitomi, Y.; Uga, Y.
10.1101/2020.12.11.421685 — plant biology — Posted on 2020-12-11
2526 Cytoplasmic physical state governs the influence of oxygen on Pinus densiflora seed ageing
Gerna, D.; Ballesteros, D.; Stoeggl, W. M.; Arc, E.; Seal, C.; Na, C.-S.; Kranner, I.; Roach, T.
10.1101/2020.12.11.421446 — plant biology — Posted on 2020-12-11
2530 Phagocytosis by stroma confounds co-culture studies
Herbst, S. A.; Stolarczyk, M.; Becirovic, T.; Liu, Y.; Kolb, C.; Herling, M.; Müller-Tidow, C.; Dietrich, S.
10.1101/2020.12.11.417923 — cancer biology — Posted on 2020-12-11
2531 Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma
Bischoff, P.; Trinks, A.; Obermayer, B.; Pett, J. P.; Lehmann, A.; Jurmeister, P.; Elsner, A.; Dziodzio, T.; Rückert, J.-C.; Neudecker, J.; Falk, C.; Beule, D.; Sers, C.; Morkel, M.; Horst, D.; Blüthgen, N.; Klauschen, F.
10.1101/2020.12.11.419606 — cancer biology — Posted on 2020-12-11
2533 CEDAR, an online resource for the reporting and exploration of complexome profiling data
van Strien, J.; Haupt, A.; Schulte, U.; Braun, H.-P.; Cabrero-Orefice, A.; Choudhary, J. S.; Evers, F.; Fernandez-Vizarra, E.; Guerrero-Castillo, S.; Kooij, T. W. A.; Palenikova, P.; Pardo, M.; Ugalde, C.; Wittig, I.; Wohlbrand, L.; Brandt, U.; Arnold, S.; Huynen, M.
10.1101/2020.12.11.421172 — bioinformatics — Posted on 2020-12-11
2534 CellMixS: quantifying and visualizing batch effects in single cell RNA-seq data
Luetge, A.; Zyprych-Walczak, J.; Brykczynska Kunzmann, U.; Crowell, H. L.; Calini, D.; Malhotra, D.; Soneson, C.; Robinson, M. D.
10.1101/2020.12.11.420885 — bioinformatics — Posted on 2020-12-11
2536 Developmental effects on pattern visual evoked potentials characterized by principal component analysis
Patterson Gentile, C.; Joshi, N. R.; Ciuffreda, K.; Arbogast, K.; Master, C.; Aguirre, G.
10.1101/2020.12.11.420158 — neuroscience — Posted on 2020-12-11
2538 Real-time Synthesis of Imagined Speech Processes from Minimally Invasive Recordings of Neural Activity
Angrick, M.; Ottenhoff, M.; Diener, L.; Ivucic, D.; Ivucic, G.; Goulis, S.; Saal, J.; Colon, A. J.; Wagner, L.; Krusienski, D. J.; Kubben, P. L.; Schultz, T.; Herff, C.
10.1101/2020.12.11.421149 — neuroscience — Posted on 2020-12-11
2540 Role of two metacaspases in development and pathogenicity of the Rice Blast fungus, Magnaporthe oryzae
Fernandez, J.; Lopezz, V.; Kinch, L.; Pfeifer, M. A.; Gray, H. A.; Orth, N.; Grishin, N. V.; Khang, C. H.; Orth, K.
10.1101/2020.12.10.420794 — microbiology — Posted on 2020-12-11
2542 Coexistence of amyloid-β and Tau hyperphosphorylation rescues cognitive and electrophysiological deficiencies in a mouse model of Alzheimer's disease
Davila-Bouziguet, E.; Casoliba-Melich, A.; Targa-Fabra, G.; Galera-Lopez, L.; Ozaita, A.; Maldonado, R.; Delgado-Garcia, J. M.; Gruart, A.; Avila, J.; Soriano, E.; Pascual, M.
10.1101/2020.12.10.417907 — neuroscience — Posted on 2020-12-11
2552 Genetic Fine-mapping with Dense Linkage Disequilibrium Blocks: genetics of nicotine dependence
Mo, C.; Ye, Z.; Hatch, K.; Zhang, Y.; Wu, Q.; Liu, S.; Kochunov, P.; Hong, L. E.; MA, T.; Chen, S.
10.1101/2020.12.10.420216 — genetics — Posted on 2020-12-11
2554 Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis
Ng, B.; Widjaja, A. A.; Viswanathan, S.; Dong, J.; Chothani, S.; Lim, S.; Shekeran, S. G.; Tan, J.; Schafer, S.; Cook, S. A.
10.1101/2020.12.10.420695 — molecular biology — Posted on 2020-12-11
2557 Plasma neutralizing antibodies in an infant with interclade HIV-1 superinfection preferentially neutralize superinfecting HIV-1 strains
Mishra, N.; Sharma, S.; Dobhal, A.; Kumar, S.; Chawla, H.; Singh, S.; Singh, R.; Das, B. K.; Lodha, R.; Kabra, S. K.; Luthra, K.
10.1101/2020.12.10.420703 — immunology — Posted on 2020-12-11
2558 Tuning electrical stimulation of the cervical vagus nerve for abdominal signaling while reducing cardiovascular side effects
Horn, C.; Forssell, M.; Sciullo, M.; Harms, J. E.; Fulton, S.; Mou, C.; Sun, F.; Simpson, T. W.; Xiao, G.; Fisher, L. E.; Bettinger, C.; Fedder, G. K.
10.1101/2020.12.10.420398 — neuroscience — Posted on 2020-12-11
2560 Persistent Inward Currents Increase With The Level Of Voluntary Drive In Plantar Flexor Low-Threshold Motor Units
Orssatto, L. B. R.; Mackay, K.; Shield, A. J.; Sakugawa, R. L.; Blazevich, A. J.; Trajano, G. S.
10.1101/2020.12.11.420570 — neuroscience — Posted on 2020-12-11
2562 Evolutionarily ancient role of cholecystokinin-type neuropeptide signalling as an inhibitory regulator of feeding-related processes revealed in an echinoderm
Tinoco, A. B.; Barreiro-Iglesias, A.; Yanez Guerra, L. A.; Delroisse, J.; Zhang, Y.; Gunner, E. F.; Zampronio, C.; Jones, A. M.; Egertova, M.; Elphick, M. R.
10.1101/2020.12.11.417543 — physiology — Posted on 2020-12-11
2563 Integrative genomics identifies lncRNA regulatory networks across 1,044 pediatric leukemias and solid tumors
Modi, A.; Lopez, G.; Conkrite, K. L.; Leung, T. C.; Ramanan, S.; Cheung, D.; Su, C.; Manduchi, E.; Johnson, M. E.; Gadd, S.; Zhang, J.; Smith, M. A.; Guidry Auvil, J. M.; Gerhard, D. S.; Meshinchi, S.; Perlman, E. J.; Hunger, S. P.; Maris, J. M.; Wells, A. D.; Grant, S. F. A.; Diskin, S. J.
10.1101/2020.12.10.420257 — cancer biology — Posted on 2020-12-11
2565 Assembling Long Accurate Reads Using de Bruijn Graphs
Bankevich, A.; Bzikadze, A. V.; Kolmogorov, M.; Pevzner, P.
10.1101/2020.12.10.420448 — bioinformatics — Posted on 2020-12-11
2571 Three-dimensional spatial transcriptomics uncovers cell type dynamics in the rheumatoid arthritis synovium
Vickovic, S.; Schapiro, D.; Carlberg, K.; Loetstedt, B.; Larsson, L.; Korotkova, M.; Hensvold, A. H.; Catrina, A. I.; Sorger, P. K.; Malmstroem, V.; Regev, A.; Stahl, P. L.
10.1101/2020.12.10.420463 — genomics — Posted on 2020-12-11
2579 First Glimpse of Gut Microbiota of Quarantine Insects in China
Yu, Y.; Wang, Q.; Zhou, P.; Lv, N.; Li, W.; Zhao, F.; Zhu, S.; Liu, D.
10.1101/2020.12.10.420612 — microbiology — Posted on 2020-12-11
2584 Regions of Highly Recurrent Electrogram Morphology at Sites of Low Cycle Length Accurately Reflect Arrhythmogenic Substrate for Atrial Fibrillation - Implications For a New, Mechanism Guided Therapeutic Approach for Atrial Fibrillation
Yoo, S.; Rottmann, M.; Ng, J.; Johnson, D. A.; Shanab, B. M.; Pfenniger, A.; Geist, G. E.; Mandava, S.; Burrell, A.; Zhang, W.; Wasserstrom, J. A.; Knight, B. P.; Passman, R.; Goldberger, J.; Arora, R.
10.1101/2020.12.10.419754 — physiology — Posted on 2020-12-11
2585 The first dinosaur egg remains a mystery
Legendre, L. J.; Rubilar-Rogers, D.; Vargas, A. O.; Clarke, J. A.
10.1101/2020.12.10.406678 — paleontology — Posted on 2020-12-11
2586 ORMDL1 is upregulated and associated with favorable outcome in colorectal cancer
Wang, Q.; Liu, W.; Chen, S.; Luo, Q.; Li, Y.; Peng, S.; Wang, H.; Liu, X.; Chen, D.
10.1101/2020.12.10.420497 — cancer biology — Posted on 2020-12-11
2588 Activity-based urinary biomarkers of response and resistance to checkpoint blockade immunotherapy
Mac, Q. D.; Xu, C.; Bowen, J. R.; Sivakumar, A.; Phuengkham, H.; Su, F.-Y.; Stentz, S. Z.; Sim, H.; Harris, A. M.; Li, T. T.; Qiu, P.; Kwong, G. A.
10.1101/2020.12.10.420265 — bioengineering — Posted on 2020-12-11
2591 Effects of Malaysian strains of Toxoplasma gondii on behaviours and their possible risk in schizophrenia-like rat model
Wana, M. N.; Watanabe, M.; Chiroma, S. M.; Unyah, N. Z.; Abdullahi, S. A.; Mahdi, O.; Alapid, A. A. I.; Nordin, S.; Basir, R.; Moklas, M. A. M.; Abd. Majid, R.
10.1101/2020.12.10.418301 — animal behavior and cognition — Posted on 2020-12-11
2593 Aiming off the target: studying repetitive DNA using target capture sequencing reads
Costa, L.; Marques, A.; Buddenhagen, C.; Thomas, W. W.; Huettel, B.; Schubert, V.; Dodsworth, S.; Houben, A.; Souza, G.; Pedrosa-Harand, A.
10.1101/2020.12.10.419515 — genomics — Posted on 2020-12-11
2594 A broad exome study of the genetic architecture of asthma reveals novel patient subgroups
Cameron-Christie, S.; Mackay, A.; Wang, Q.; Olsson, H.; Angermann, B.; Lassi, G.; Lindgren, J.; Hühn, M.; Cameron-Christie, Y. O.; Gavala, M.; Wang, J.; Povysil, G.; Deevi, S. V. V.; Belfield, G.; Dillmann, I.; Muthas, D.; Cohen, S.; Young, S.; Platt, A.; Petrovski, S.
10.1101/2020.12.10.419663 — genomics — Posted on 2020-12-11
2596 Revisiting the Out of Africa event with a novel Deep Learning approach
Montinaro, F.; Pankratov, V.; Yelmen, B.; Pagani, L.; Mondal, M.
10.1101/2020.12.10.419069 — genetics — Posted on 2020-12-11
2597 Bacterial adaptation by a transposition burst of an invading IS element
Miller, S.; Abresch, H. E.; Ulrich, N. J.; Sano, E. B.; Demaree, A. H.; Garber, A. I.
10.1101/2020.12.10.420380 — evolutionary biology — Posted on 2020-12-11
2603 Myogenin controls via AKAP6 non-centrosomal microtubule organizing center formation at the nuclear envelope
Becker, R.; Vergarajauregui, S.; Billing, F.; Sharkova, M.; Lippolis, E.; Mamchaoui, K.; Ferrazzi, F.; Engel, F.
10.1101/2020.12.11.421263 — cell biology — Posted on 2020-12-11
2604 Highly multiplexed imaging of biosensors in live cells
Yang, J.-M.; Chi, W.-Y.; Liang, J.; Iglesias, P. A.; Huang, C.-H.
10.1101/2020.12.11.419655 — cell biology — Posted on 2020-12-11
2606 Epilepsy kinase CDKL5 is a DNA damage sensor which controls transcriptional activity at DNA breaks
Khanam, T.; Munoz, I.; Weiland, F.; Carroll, T.; Borsos, B.; Pantazi, V.; Slean, M.; Novak, M.; Toth, R.; Appleton, P.; Pankotai, T.; Zhou, H.; Rouse, J.
10.1101/2020.12.10.419747 — cell biology — Posted on 2020-12-11
2609 Identification of eight SARS-CoV-2 ORF7a deletion variants in 2,726 clinical specimens
Rosenthal, S. H.; Kagan, R. M.; Gerasimova, A.; Anderson, B.; grover, D.; Hua, M.; Owen, R.; Lacbawan, F.
10.1101/2020.12.10.418855 — microbiology — Posted on 2020-12-11
2610 The evolution of trait correlations constrains phenotypic adaptation to high CO2 in a eukaryotic alga
Walworth, N. G.; Hinners, J.; Argyle, P. A.; Leles, S. G.; Doblin, M. A.; Collins, S.; Levine, N. M.
10.1101/2020.08.04.237230 — microbiology — Posted on 2020-12-11
2611 Profound Treg perturbations correlate with COVID-19 severity
Galvan-Pena, S.; Leon, J.; Chowdhary, K.; Michelson, D. A.; Vijaykumar, B.; Yang, L.; Magnuson, A.; Manickas-Hill, Z.; Piechocka-Trocha, A.; Worrall, D. P.; Hall, K. E.; Ghebremichael, M.; Walker, B. D.; Li, J. Z.; Yu, X. G.; MGH COVID-19 Collection & Processing Team, ; Mathis, D.; Benoist, C.
10.1101/2020.12.11.416180 — immunology — Posted on 2020-12-11
2612 Osteoclasts contribute to early development of chronic inflammation by promoting dysregulated hematopoiesis and myeloid skewing
Madel, M.-B.; Ibanez, L.; Ciucci, T.; Halper, J.; Topi, M.; Garchon, H.-J.; Rouleau, M.; Mueller, C. G.; Peyrin Biroulet, L.; MOULIN, D.; Blin-Wakkach, C.; Wakkach, A.
10.1101/2020.12.09.418137 — immunology — Posted on 2020-12-11
2613 BNT162b vaccines are immunogenic and protect non-human primates against SARS-CoV-2
Vogel, A. B.; Kanevsky, I.; Che, Y.; Swanson, K. A.; Muik, A.; Vormehr, M.; Kranz, L. M.; Walzer, K. C.; Hein, S.; Gueler, A.; Loschko, J.; Maddur, M. S.; Ota-Setlik, A.; Tompkins, K.; Cole, J.; Lui, B. G.; Ziegenhals, T.; Plaschke, A.; Eisel, D.; Dany, S. C.; Fesser, S.; Erbar, S.; Bates, F.; Schneider, D.; Jesionek, B.; Saenger, B.; Wallisch, A.-K.; Feuchter, Y.; Junginger, H.; Krumm, S. A.; Heinen, A. P.; Adams-Quack, P.; Schlereth, J.; Schille, S.; Kroener, C.; de la Caridad Gueimil Garcia, R.; Hiller, T.; Fischer, L.; Sellers, R. S.; Choudhary, S.; Gonzalez, O.; Vascotto, F.; Gutman, M. R
10.1101/2020.12.11.421008 — immunology — Posted on 2020-12-11
2614 Fate mapping analysis reveals a novel dermal migratory Langerhans-like cell population
Ruedl, C.; Sheng, J.; Chen, Q.; Dong, Y. W.; Wu, X.; Mayer, J. U.; Wang, L.; Bai, X.; Liang, T.; Sung, Y. H.; Goh, W. W. B.; Ronchese, F.
10.1101/2020.12.10.419903 — immunology — Posted on 2020-12-11
2619 No behavioral evidence for rhythmic facilitation of perceptual discrimination
Lin, W. M.; Oetringer, D.; Bakker-Marshall, I.; Emmerzaal, J.; Wilsch, A.; ElShafei, H. A.; El Rassi, E.; Haegens, S.
10.1101/2020.12.10.418947 — neuroscience — Posted on 2020-12-11
2621 APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis
Ramakrishna, S.; Jhaveri, V.; Konings, S. C.; Chakraborty, S.; Holst, B.; Schmid, B.; Gouras, G. K.; Freude, K. K.; Muddashetty, R. S.
10.1101/2020.12.10.418772 — neuroscience — Posted on 2020-12-11
2622 Serum response factor is essential for synaptic maturation in the hippocampus
Krysiak, A.; Roszkowska, M.; Majchrowicz, L.; Beroun, A.; Michaluk, P.; Nader, K.; Pekała, M.; Jaworski, J.; Kondrakiewicz, L.; Puscian, A.; Knapska, E.; Kaczmarek, L.; Kalita, K.
10.1101/2020.12.10.417360 — neuroscience — Posted on 2020-12-11
2624 Increased prefrontal top-down control in older adults predicts motor performance and age-group association
Loehrer, P. A.; Nettersheim, F. S.; Oehrn, C.; Homberg, F.; Tittgemeyer, M.; Timmermann, L.; Weber, I.
10.1101/2020.12.09.417568 — neuroscience — Posted on 2020-12-11
2632 DNA methylation and survival differences associated with the type of IDH mutation in 1p/19q non-codeleted astrocytomas
Tesileanu, M.; Vallentgoed, W.; Sanson, M.; Taal, W.; Clement, P.; Wick, W.; Brandes, A.; Baurain, J.-F.; Chinot, O.; Wheeler, H.; Gill, S.; Griffin, M.; Rogers, L.; Ruda, R.; Weller, M.; McBain, C.; Reijneveld, J.; Enting, R.; Caparrotti, F.; Lesimple, T.; Clenton, S.; Gijtenbeek, A.; Lim, E.; de Vos, F.; Mulholland, P.; Taphoorn, M.; de Heer, I.; Hoogstrate, Y.; de Wit, M.; Boggiani, L.; Venneker, S.; Oosting, J.; Bovee, J.; Erridge, S.; Vogelbaum, M.; Nowak, A.; Mason, W.; Kros, J.; Wesseling, P.; Aldape, K.; Jenkins, R.; Dubbink, H.; Baumert, B.; Golfinopoulos, V.; Gorlia, T.; van den Bent
10.1101/2020.12.10.419333 — cancer biology — Posted on 2020-12-11
2634 Duplex formation between the template and the nascent strand in the transcription-regulating sequences determines the site of template switching in SARS - CoV-2
D'souza, A. R.; Buckingham, A. B.; Salasc, F.; Ingemarsdotter, C.; Iaconis, G.; Jarvis, I.; Groom, H. C. T.; Kenyon, J.; Lever, A. M. L.
10.1101/2020.12.11.416818 — bioinformatics — Posted on 2020-12-11
2638 EVs analysis in the COVID-19 era: insights on serum inactivation protocols towards downstream isolation and analysis
Frigerio, R.; Musico', A.; Brucale, M.; Ridolfi, A.; Galbiati, S.; Vago, R.; Bergamaschi, G.; Ferretti, A.; Chiari, M.; Valle, F.; Gori, A.; Cretich, M.
10.1101/2020.12.10.417758 — biochemistry — Posted on 2020-12-11
2639 Coiled coil control of diverse EGFR functions
Mozumdar, D.; Quach, K.; Doerner, A.; Schepartz, A.
10.1101/2020.12.10.419739 — biochemistry — Posted on 2020-12-11
2641 Convergent evolution of distinct immune sensor systems for fungal polygalacturonases in Brassicaceae
Zhang, L.; Hua, C.; Pruitt, R.; Qin, S.; Wang, L.; Albert, I.; Albert, M.; van Kan, J. A. L.; Nuernberger, T.
10.1101/2020.12.10.418392 — plant biology — Posted on 2020-12-11
2648 NPRL3: Direct Effects on Human Phenotypic Variability, mTOR Signaling, Subcellular mTOR Localization, Cortical Lamination, and Seizure Susceptibility
Iffland, P. H.; Everett, M. E.; Cobb-Pitstick, K. M.; Bowser, L. E.; Barnes, A. E.; Babus, J. K.; Romanowski, A.; Baybis, M.; Puffenberger, E.; Gonzaga-Jauregui, C.; Poulopoulos, A.; Carson, V. J.; Crino, P. B.
10.1101/2020.12.11.421214 — neuroscience — Posted on 2020-12-11
2651 Heartbeats entrain breathing via baroreceptor-mediated modulation of expiratory activity
Barnett, W. H.; Baekey, D. M.; Paton, J. F. R.; Dick, T. E.; Wehrwein, E. A.; Molkov, Y. I.
10.1101/2020.12.09.416776 — neuroscience — Posted on 2020-12-11
2652 Emotional Metacognition: Stimulus Valence Modulates Cardiac Arousal and Metamemory
Legrand, N.; Engen, S. S.; Correa, C.; Mathiasen, N. K.; Nikolova, N.; Fardo, F.; Allen, M.
10.1101/2020.06.10.144428 — neuroscience — Posted on 2020-12-11
2653 Redox protein Memo1 coordinates FGF23-driven signaling and small Rho-GTPases in the mouse kidney
Bartos, K.; Ramakrishnan, S. K.; Braga-Lagache, S.; Haenzi, B.; Durussel, F.; Prakash Sridharan, A.; Zhu, Y.; Sheehan, D.; Hynes, N. E.; Bonny, O.; Moor, M. B.
10.1101/2020.12.04.402511 — biochemistry — Posted on 2020-12-11
2654 Diverse natural variants suppress mutations in hundreds of essential genes
Parts, L.; Batte, A.; Lopes, M.; Yuen, M. W.; Laver, M.; San Luis, B.-J.; Yue, J.-X.; Pons, C.; Eray, E.; Aloy, P.; Liti, G.; van Leeuwen, J.
10.1101/2020.11.24.395855 — genetics — Posted on 2020-12-11
2655 BBLN-1 is essential for intermediate filamentorganization and apical membrane morphology
Remmelzwaal, S.; Geisler, F.; Stucchi, R.; van der Horst, S.; Pasolli, M.; Kroll, J. R.; Jarosinska, O. D.; Akhmanova, A.; Richardson, C. A.; Altelaar, A. F. M.; Leube, R. E.; Ramalho, J. J.; Boxem, M.
10.1101/2020.12.04.411520 — developmental biology — Posted on 2020-12-11
2656 Efficient inhibition of SARS-CoV-2 strains by a novel ACE2-IgG4-Fc fusion protein with a stabilized hinge region
Svilenov, H. L.; Sacherl, J.; Reiter, A.; Wolff, L.; Chen, C.-C.; Stern, M.; Wachs, F.-P.; Simonavicius, N.; Pippig, S.; Wolschin, F.; Buchner, J.; Brockmeyer, C.; Protzer, U.
10.1101/2020.12.06.413443 — immunology — Posted on 2020-12-11
2659 The hybrid nature of task-evoked activity: Inside-out neural dynamics in intracranial EEG and Deep Learning
Wolff, A.; Chen, L.; Tumati, S.; Golesorkhi, M.; Gomez-Pilar, J.; Hu, J.; Jiang, S.; Mao, Y.; Longtin, A.; Northoff, G.
10.1101/2020.12.09.417774 — neuroscience — Posted on 2020-12-11
2661 Cortical resonance selects coherent input
Lewis, C. M.; Ni, J.; Wunderle, T.; Jendritza, P. M.; Lazar, A.; Diester, I.; Fries, P.
10.1101/2020.12.09.417782 — neuroscience — Posted on 2020-12-11
2663 ARP-T1 is a ciliogenesis protein associated with a novel ciliopathy in inherited basal cell cancer, Bazex-Dupre-Christol Syndrome
Park, H.-S.; Papanastasi, E.; Blanchard, G.; Chiticariu, E.; Bachmann, D.; Plomann, M.; Morice-Picard, F.; Vabres, P.; Smahi, A.; Huber, M.; Pich, C.; Hohl, D.
10.1101/2019.12.16.877498 — cancer biology — Posted on 2020-12-11
2666 distinct: a novel approach to differential distribution analyses
Tiberi, S.; Crowell, H. L.; Weber, L. M.; Samartsidis, P.; Robinson, M. D.
10.1101/2020.11.24.394213 — bioinformatics — Posted on 2020-12-11
2667 Whole Genome Sequencing for Revealing the Point Mutations of SARS-CoV-2 Genome in Bangladeshi Isolates and their Structural Effects on Viral Proteins
Hossain, M. U.; Ahammad, I.; Emon, M. T. H.; Bhattacharjee, A.; Chowdhury, Z. M.; Mosaib, M. G.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2020.12.05.413377 — bioinformatics — Posted on 2020-12-11
2668 A Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome
Sterrett, M. C.; Enyenihi, L.; Leung, S. W.; Hess, L.; Strassler, S. E.; Farchi, D.; Lee, R. S.; Withers, E. S.; Kremsky, I.; Baker, R. E.; Basrai, M. A.; Van Hoof, A.; Fasken, M. B.; Corbett, A. H.
10.1101/2020.12.06.413658 — genetics — Posted on 2020-12-11
2671 A semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial differentiation
Ostrop, J.; Zwiggelaar, R.; Pedersen, M. T.; Gerbe, F.; Bösl, K.; Lindholm, H. T.; Diez-Sanchez, A.; Parmar, N.; Radetzki, S.; von Kries, J. P.; Jay, P.; Jensen, K. B.; Arrowsmith, C.; Oudhoff, M. J.
10.1101/2020.07.23.217414 — cell biology — Posted on 2020-12-11
2672 Longitudinal linked read sequencing reveals ecological and evolutionary responses of a human gut microbiome during antibiotic treatment
Roodgar, M.; Good, B. H.; Garud, N. R.; Martis, S.; Avula, M.; Zhou, W.; Lancaster, S.; Lee, H.; Babveyh, A.; Nesamoney, S.; Pollard, K. S.; Snyder, M. P.
10.1101/2019.12.21.886093 — microbiology — Posted on 2020-12-11
2675 Unveiling the sensory and interneuronal pathways of the neuroendocrine connectome in Drosophila
Hückesfeld, S.; Schlegel, P.; Miroschnikow, A.; Schoofs, A.; Zinke, I.; Haubrich, A. N.; Schneider-Mizell, C. M.; Truman, J. W.; Fetter, R. D.; Cardona, A.; Pankratz, M. J.
10.1101/2020.10.22.350306 — neuroscience — Posted on 2020-12-11
2676 Combined deletion of free fatty-acid receptors 1 and 4 minimally impacts glucose homeostasis in mice
Croze, M. L.; Guillaume, A.; Ethier, M.; Fergusson, G.; Tremblay, C.; Campbell, S. A.; Maachi, H.; Ghislain, J.; Poitout, V.
10.1101/2020.08.04.236471 — physiology — Posted on 2020-12-11
2677 Acquired RAD51C promoter methylation loss causes PARP inhibitor resistance in high grade serous ovarian carcinoma
Nesic, K.; Kondrashova, O.; Hurley, R. M.; McGehee, C.; Vandenberg, C. J.; Ho, G.-Y.; Lieschke, E.; Dall, G.; Bound, N.; Shield-Artin, K.; Radke, M. R.; Musafer, A.; Qing Chai, Z.; Harrell, M. I.; Kee, D.; Olesen, I.; McNally, O.; Traficante, N.; DeFazio, A.; Bowtell, D.; Swisher, E. M.; Weroha, J.; Nones, K.; Waddell, N.; Kaufmann, S. H.; Dobrovic, A.; Wakefield, M. J.; Scott, C. L.
10.1101/2020.12.10.419176 — cancer biology — Posted on 2020-12-11
2679 A membrane-associated condensate drives paternal epigenetic inheritance in C. elegans
Schreier, J.; Dietz, S.; Domingues, A.; Seistrup, A.-S.; Nguyen, D. A.; Gleason, E.; Ling, H.; l'Hernault, S.; Phillips, C. M.; Butter, F.; Ketting, R.
10.1101/2020.12.10.417311 — cell biology — Posted on 2020-12-11
2680 Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors
Sam, P.; Calzada, E.; Acoba, M. G.; Zhao, T.; Watanabe, Y.; Nejatfard, A.; Trinidad, J.; Shutt, T.; Neal, S. E.; Claypool, S. M.
10.1101/2020.12.10.416495 — cell biology — Posted on 2020-12-11
2682 Surprising Phenotypic Diversity of Cancer-associated mutations of Gly 34 in the Histone H3 tail
Lowe, B. R.; Yadav, R. K.; Henry, R. A.; Schreiner, P.; Matsuda, A.; Fernandez, A. G.; Finkelstein, D.; Campbell, M.; Kallappagoudar, S.; Jablonowski, C. M.; Andrews, A. J.; Hiraoka, Y.; Partridge, J. F.
10.1101/2020.12.10.419184 — molecular biology — Posted on 2020-12-11
2684 BAP1 activity regulates PcG occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition
Conway, E.; Rossi, F.; Tamburri, S.; Ponzo, E.; Ferrari, K. J.; Zanotti, M.; Fernandez-Perez, D.; Manganaro, D.; Rodighiero, S.; Pasini, D.
10.1101/2020.12.10.419309 — molecular biology — Posted on 2020-12-11
2685 Metabolic reprogramming and host-immune response against Crimean-Congo Hemorrhagic Fever Viruses
Neogi, U.; Elaldi, N.; Appelberg, S.; Ambikan, A.; Kennedy, E.; D. Dowall, S.; Bagci, B. K.; Gupta, S.; Rodriguez, J. E.; Svensson-Akusjärvi, S.; Monteil, V.; Vegvari, A.; Weber, F.; Hewson, R.; Mirazimi, A.
10.1101/2020.12.10.419697 — microbiology — Posted on 2020-12-11
2692 Deep learning enables rapid and robust analysis of fluorescence lifetime imaging in photon-starved conditions
Chen, Y.-I.; Chang, Y.-J.; Liao, S.-C.; Nguyen, T. D.; Yang, J.; Kuo, Y.-A.; Hong, S.; Liu, Y.-L.; Rylander, H. G.; Santacruz, S. R.; Yankeelov, T. E.; Yeh, H.-C.
10.1101/2020.12.02.408195 — cell biology — Posted on 2020-12-10
2693 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
Pras, A.; Houben, B.; Aprile, F. A.; Seinstra, R.; Gallardo, R.; Janssen, L.; Hogewerf, W.; De Vleeschouwer, M.; Mata-Cabana, A.; Koopman, M.; Stroo, E.; De Vries, M.; Edwards, S. L.; Vendruscolo, M.; Falsone, F.; Rousseau, F.; Schymkowitz, J.; Nollen, E. A. A.
10.1101/2020.12.09.417709 — molecular biology — Posted on 2020-12-10
2694 Unbiased antimicrobial resistance detection from clinical bacterial isolates using proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Schneider, A.; Lasch, P.; Joerg, D.
10.1101/2020.11.17.386540 — microbiology — Posted on 2020-12-10
2695 Enhanced Brain Imaging Genetics in UK Biobank
Smith, S. M.; Douaud, G.; Chen, W.; Hanayik, T.; Alfaro-Almagro, F.; Sharp, K.; Elliott, L. T.
10.1101/2020.07.27.223545 — neuroscience — Posted on 2020-12-10
2698 Samplot: A Platform for Structural Variant Visual Validation and Automated Filtering
Belyeu, J. R.; Chowdhury, M.; Brown, J.; Pedersen, B. S.; Cormier, M. J.; Quinlan, A.; Layer, R. M.
10.1101/2020.09.23.310110 — genetics — Posted on 2020-12-10
2700 Consistent variations in personality traits and their potential for genetic improvement of biocontrol agents: Trichogramma evanescens as a case study
Lartigue, S.; Yalaoui, M.; Belliard, J.; Caravel, C.; Jeandroz, L.; Groussier, G.; Calcagno, V.; Louapre, P.; Dechaume-Moncharmont, F.-X.; Malausa, T.; Moreau, J.
10.1101/2020.08.21.257881 — ecology — Posted on 2020-12-10
2703 Multi-modal imaging of a single postmortem mouse brain over five orders of magnitude of resolution
Foxley, S.; Sampathkumar, V.; De Andrade, V.; Trinkle, S.; Sorokina, A.; Norwood, K.; La Riviere, P.; Kasthuri, N.
10.1101/2020.10.07.329789 — neuroscience — Posted on 2020-12-10
2705 A sinusoidal transform of the visual field in cortical area V2
Sedigh-Sarvestani, M.; Lee, K.-S.; Satterfield, R.; Shultz, N.; Fitzpatrick, D.
10.1101/2020.12.08.416651 — neuroscience — Posted on 2020-12-10
2709 Novel xylan degrading enzymes from polysaccharide utilizing loci of Prevotella copri DSM18205
Linares-Pastén, J. A.; Hero, J. S.; Pisa, J. H.; Teixeira, C.; Nyman, M.; Adlercreutz, P.; Martinez, M. A.; Nordberg Karlsson, E.
10.1101/2020.12.10.419226 — biochemistry — Posted on 2020-12-10
2710 A non-invasive radar system for automated behavioural tracking: application to sheep
Dore, A.; Pasquaretta, C.; Henry, D.; Ricard, E.; Bompard, J.-F.; Bonneau, M.; Boissy, A.; Hazard, D.; Aubert, H.; Lihoreau, M.
10.1101/2020.12.09.418038 — animal behavior and cognition — Posted on 2020-12-10
2712 Stressful times in a climate crisis: how will aphids respond to more frequent drought?
Leybourne, D. J.; Preedy, K. F.; Valentine, T. A.; Bos, J. I.; Karley, A. J.
10.1101/2020.06.24.168112 — ecology — Posted on 2020-12-10
2715 Defective oligodendrocyte development and function in an RNA polymerase III mutant leukodystrophic mouse
Merheb, E.; Cui, M.-H.; DuBois, J. C.; Branch, C. A.; Gulinello, M.; Shafit-Zagardo, B.; Moir, R. D.; Willis, I. M.
10.1101/2020.12.09.418657 — neuroscience — Posted on 2020-12-10
2716 Segregating domain-general from emotional context-specific inhibitory control systems - ventral striatum and orbitofrontal cortex serve as emotion-cognition integration hubs
Zhuang, Q.; Xu, L.; Zhou, F.; Yao, S.; Zheng, X.; Zhou, X.; Li, J.; Xu, X.; Fu, M.; Li, K.; Vatansever, D.; Kendrick, K. M.; Becker, B.
10.1101/2020.12.09.418830 — neuroscience — Posted on 2020-12-10
2717 MRI- and histologically derived neuroanatomical atlas of the Ambystoma mexicanum (axolotl)
Lazcano, I.; Cisneros-Mejorado, A.; Concha, L.; Ortiz-Retana, J. J.; Garza-Villarreal, E. A.; Orozco, A.
10.1101/2020.12.09.418566 — neuroscience — Posted on 2020-12-10
2721 Hidden limbs in the limbless skink Brachymeles lukbani: developmental observations
Smith-Paredes, D.; Griffith, O.; Fabbri, M.; Yohe, L.; Blackburn, D. G.; Siler, C. D.; Bhullar, B.-A. S.; Wagner, G.
10.1101/2020.12.09.418483 — evolutionary biology — Posted on 2020-12-10
2724 GOLIATH regulates LDLR availability and plasma LDL cholesterol levels
Clifford, B. L.; Jarrett, K. E.; Cheng, J.; Cheng, A.; Seldin, M.; Morand, P.; Lee, R.; Baldan, A.; de Aguiar Vallim, T. Q.; Tarling, E. J.
10.1101/2020.12.09.415323 — molecular biology — Posted on 2020-12-10
2728 Phospholipid Metabolism Is Associated with HIV Rebound Upon Treatment Interruption
Giron, L. B.; Papasavvas, E.; Yin, X.; Goldman, A.; Tang, H.-Y.; Palmer, C.; Landay, A. L.; Li, J. Z.; Koethe, J.; Mounzer, K. C.; Kostman, J.; Liu, Q.; Montaner, L. J.; Abdel-Mohsen, M.
10.1101/2020.12.09.418814 — microbiology — Posted on 2020-12-10
2729 PD-L1 - PD-1 interactions limit effector Treg cell populations at homeostasis and during infection
Perry, J. A.; Clark, J. T.; Gullicksrud, J.; DeLong, J.; Shallberg, L.; Douglas, B.; Hart, A. P.; Konradt, C.; Park, J.; Glatman Zaretsky, A.; de Waal Malefyt, R.; Christian, D. A.; Sharpe, A. H.; Hunter, C. A.
10.1101/2020.12.09.416990 — immunology — Posted on 2020-12-10
2730 Single-cell RNA sequencing reveals time- and sex-specific responses of spinal cord microglia to peripheral nerve injury and links ApoE to neuropathic pain
Tansley, S.; Uttam, S.; Guzman, A. U.; Yaqubi, M.; Pacis, A.; Parisien, M.; Rabau, O.; Haglund, L.; Ouellet, J.; Santaguida, C.; Ragoussis, I.; Zhang, J.; Salter, M. W.; Diatchenko, L.; Healy, L. M.; Mogil, J. S.; Khoutorsky, A.
10.1101/2020.12.09.418541 — neuroscience — Posted on 2020-12-10
2731 Distinct Neuropeptide-Receptor Modules Regulate a Sex-Specific Behavioral Response to a Pheromone
Reilly, D. K.; McGlame, E. J.; Vandewyer, E.; Robidoux, A. N.; Northcott, H. T.; Joyce, W.; Alkema, M. J.; Gegear, R. J.; Beets, I.; Srinivasan, J.
10.1101/2020.12.09.417857 — neuroscience — Posted on 2020-12-10
2732 Improved Photocleavable Proteins with Faster and More Efficient Dissociation
Lu, X.; Wen, Y.; Zhang, S.; Zhang, W.; Chen, Y.; Shen, Y.; Lemieux, J.; Campbell, R. E.
10.1101/2020.12.10.419556 — synthetic biology — Posted on 2020-12-10
2733 In-House Forecasting of Crop Latitude Adaptation through a Daylength-sensing-based Environment Adaptation Simulator (DEAS)
Qiu, L.; Wu, Q.; Wang, X.; Zhuang, G.; Han, J.; Wang, H.; Shang, Z.; Tian, W.; Chen, Z.; Lin, Z.; He, H.; Hu, J.; Lv, Q.; Ren, J.; Xu, J.; Li, C.; Wang, X.; Li, Y.; Li, S.; Huang, R.; Chen, X.; Zhang, C.; Lu, M.; Liang, C.; Qin, P.; Huang, X.; Li, S.; Ouyang, X.
10.1101/2020.12.09.418558 — plant biology — Posted on 2020-12-10
2735 Plasma glutathione status as indicator of pre-analytical centrifugation delay
Tamara, T.; Bordag, N.; Zuegner, E.; Al-Bagdhadi, A.; Schinagl, M.; Birner-Gruenberger, R.; Schittmayer, M.
10.1101/2020.12.09.417386 — pathology — Posted on 2020-12-10
2737 An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer
Artemov, A. V.; Zhenilo, S.; Kaplun, D.; Starshin, A.; Sokolov, A.; Mazur, A. M.; Szpotan, J.; Gawronski, M.; Modrzejewska, M.; Gackowski, D.; Prokhortchouk, E. B.
10.1101/2020.12.09.418616 — cancer biology — Posted on 2020-12-10
2738 In Vivo CRISPR Screens Identify E3 Ligase Cop1 as a Modulator of Macrophage Infiltration and Cancer Immunotherapy Target
Wang, X.; Tokheim, C.; Wang, B.; Gu, S. S.; Tang, Q.; Li, Y.; Traugh, N.; Zhang, Y.; Li, Z. W.; Zhang, B.; Fu, J.; Xiao, T.; Li, W.; Meyer, C. A.; Chu, J.; Jiang, P.; Cejas, P.; Lim, K.; LONG, H. W.; Brown, M.; Liu, X. S.
10.1101/2020.12.09.418012 — cancer biology — Posted on 2020-12-10
2739 Within-host genomics of SARS-CoV-2
Lythgoe, K. A.; Hall, M. D.; Ferretti, L.; de Cesare, M.; MacIntyre-Cockett, G.; Trebes, A.; Andersson, M.; Otecko, N.; Wise, E. L.; Moore, N.; Lynch, J.; Kidd, S.; Cortes, N.; Mori, M.; Williams, R.; Vernet, G.; Justice, A.; Green, A.; Nicholls, S. M.; Ansari, M. A.; Abeler-Dorner, L.; Moore, C. E.; Peto, T. E. A.; Eyre, D. W.; Shaw, R.; Simmonds, P.; Buck, D.; Todd, J. A.; Connor, T. R.; da Silva Filipe, A.; Shephard, J.; Thomson, E. C.; The COVID-19 Genomics UK (COG-UK) Consortium, ; Bonsall, D.; Fraser, C.; Golubchik, T.
10.1101/2020.05.28.118992 — genomics — Posted on 2020-12-10
2740 The endosymbiotic origins of the apicoplast link fever-survival and artemisinin-resistance in the malaria parasite
Zhang, M.; Wang, C.; Oberstaller, J.; Thomas, P.; Otto, T. D.; Boyapalle, S.; Adapa, S. R.; Button-Simons, K.; Mayho, M.; Rayner, J. C.; Ferdig, M. T.; Jiang, R. H. Y.; Adams, J. H.
10.1101/2020.12.10.419788 — genomics — Posted on 2020-12-10
2742 Expanding the range of editable targets in the wheat genome using the variants of the Cas12a and Cas9 nucleases
Wang, W.; Tian, B.; Pan, Q.; Chen, Y.; He, F.; Bai, G.; Akhunova, A.; Trick, H.; Akhunov, E.
10.1101/2020.12.09.418624 — genetics — Posted on 2020-12-10
2743 A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne-Kalscheuer syndrome
Bustos, F.; Espejo-Serrano, C.; Segarra-Fas, A.; Eaton, A. J.; Kernohan, K. D.; Wilson, M. J.; Riley, L. G.; Findlay, G. M.
10.1101/2020.12.09.417873 — developmental biology — Posted on 2020-12-10
2744 Direct differentiation of Dental Pulp Pluripotent-like Stem Cells differentiation into Hepatocyte-like Cells
Gil-Recio, C.; Montori, S.; Vallejo, C.; Al Demour, S.; Ferres-Padro, E.; Barajas, M.; Martin, C.; Al Madhoun, A.; Atari, M.
10.1101/2020.12.09.418780 — cell biology — Posted on 2020-12-10
2746 Cross-neutralization of SARS-CoV-2 by HIV-1 specific broadly neutralizing antibodies and polyclonal plasma
Mishra, N.; Kumar, S.; Singh, S.; Bansal, T.; Jain, N.; Saluja, S.; Palanichamy, J. K.; Mir, R. A.; Sinha, S.; Luthra, K.
10.1101/2020.12.09.418806 — immunology — Posted on 2020-12-10
2747 How accurate are citations of frequently cited papers in biomedical literature?
Pavlovic, V.; Weissgerber, T.; Stanisavljevic, D.; Pekmezovic, T.; Garovic, V.; Milic, N.; CITE investigators,
10.1101/2020.12.10.419424 — scientific communication and education — Posted on 2020-12-10
2748 SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential
Vithani, N.; Ward, M. D.; Zimmerman, M. I.; Novak, B.; Borowsky, J. H.; Singh, S.; Bowman, G. R.
10.1101/2020.12.10.420109 — biophysics — Posted on 2020-12-10
2751 TMT-Opsins differentially modulate medaka brain function in a context-dependent fashion
Fontinha, B. M.; Zekoll, T.; Al-Rawi, M.; Gallach, M.; Reithofer, F.; Barker, A. J.; Hofbauer, M.; Fischer, R.; von Haeseler, A.; Baier, H.; Tessmar-Raible, K.
10.1101/698480 — neuroscience — Posted on 2020-12-10
2753 Prediction Of Eye, Hair And Skin Color In Admixed Populations Of Latin America
Palmal, S.; Adhikari, K.; Mendoza-Revilla, J.; Fuentes-Guajardo, M.; Silva de Cerqueira, C. C.; Chacon-Duque, J. C.; Sohail, A.; Hurtado, M.; Villegas, V.; Granja, V.; Jaramillo, C.; Arias, W.; Barquera Lozano, R.; Everardo Martinez, P.; Gomez-Valdes, J.; Villamil-Ramirez, H.; Hunemeier, T.; Ramallo, V.; Gonzalez-Jose, R.; Schuler-Faccini, L.; Bortolini, M.-C.; Acuna-Alonzo, V.; Canizales-Quinteros, S.; Gallo, C.; Poletti, G.; Bedoya, G.; Rothhammer, F.; Balding, D.; Faux, P.; Ruiz-Linares, A.
10.1101/2020.12.09.415901 — genetics — Posted on 2020-12-10
2754 Universal probabilistic programming offers a powerful approach to statistical phylogenetics
Ronquist, F.; Kudlicka, J.; Senderov, V.; Borgström, J.; Lartillot, N.; Lunden, D.; Murray, L.; Schön, T. B.; Broman, D.
10.1101/2020.06.16.154443 — evolutionary biology — Posted on 2020-12-10
2755 An interactive viral genome evolution network analysis system enabling rapid large-scale molecular tracing of SARS-CoV-2
Ling, Y.; Cao, R.; Qian, J.; Li, J.; Zhou, H.; Yuan, L.; Wang, Z.; Zheng, G.; Zhao, G.; Li, Y.; Wang, Z.; Zhang, G.
10.1101/2020.12.09.417121 — evolutionary biology — Posted on 2020-12-10
2757 Betulonic acid derivatives inhibiting coronavirus replication in cell culture via the nsp15 endoribonuclease
Krasniqi, B.; Stevaert, A.; Van Loy, B.; Nguyen, T.; Thomas, J.; Vandeput, J.; Jochmans, D.; Thiel, V.; Dijkman, R.; Dehaen, W.; Voet, A.; Naesens, L.
10.1101/2020.12.10.418996 — microbiology — Posted on 2020-12-10
2758 Molnupiravir (EIDD-2801) inhibits SARS-CoV2 replication in Syrian hamsters model
Abdelnabi, R.; Foo, C. S.; Kaptein, S. J. F.; Zhang, X.; Langendries, L.; Vangeel, L.; Vergote, V.; Heylen, E.; Dallmeier, K.; Chatterjee, A.; De Jonghe, S.; Weynand, B.; Neyts, J.
10.1101/2020.12.10.419242 — microbiology — Posted on 2020-12-10
2759 A single dose, BCG-adjuvanted SARS-CoV-2 vaccine induces Th1-polarized immunity and high-titre neutralizing antibodies in mice
Counoupas, C.; Stella, A.; Bhattacharyya, N.; Grey, A.; Patel, K.; Ferguson, A.; Hutchings, O.; Feng, C.; Palendira, U.; Steain, M.; Aggarwal, A.; Low, J.; Mackay, J.; Kelleher, A.; Britton, W.; Turville, S.; Triccas, J. A.
10.1101/2020.12.10.419044 — microbiology — Posted on 2020-12-10
2760 Uncovering the Organization of Neural Circuits with Generalized Phase Locking Analysis
Safavi, S.; Panagiotaropoulos, T. I.; Kapoor, V.; Ramirez-Villegas, J. F.; Logothetis, N. K.; Besserve, M.
10.1101/2020.12.09.413401 — neuroscience — Posted on 2020-12-10
2762 Altered functional integration of brain activity is a marker of impaired cognitive performance following sleep deprivation
Cross, N.; Pomares, F. B.; Nguyen, A.; Perrault, A. A.; Jegou, A.; Uji, M.; Lee, K.; Razavipour, F.; Ali, O. B. K.; Aydin, U.; Benali, H.; Grova, C.; Dang-Vu, T. T.
10.1101/2020.11.28.402305 — neuroscience — Posted on 2020-12-10
2765 SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray
Pyrc, K.; Milewska, A.; Duran, E. B.; Botwina, P.; Lopes, R.; Arenas-Pinto, A.; Badr, M.; Mellor, R.; Kalber, T.; Fernandez-Reyes, D.; Schatzlein, A. G.; Uchegbu, I. F.
10.1101/2020.12.10.413609 — pharmacology and toxicology — Posted on 2020-12-10
2769 The RNA helicase DHX30 coordinates cytoplasmic translation and mitochondrial function contributing to cancer cell survival
Bosco, B.; Rossi, A.; Rizzotto, D.; Giorgetta, S.; Perzolli, A.; Bonollo, F.; Gaucherot, A.; Catez, F.; Diaz, J.-J.; Dassi, E.; Inga, A.
10.1101/2020.07.13.196709 — molecular biology — Posted on 2020-12-10
2774 Peptide-based GIP receptor inhibition produces limited metabolic improvements in mice whether alone or combined with GLP-1 agonism.
West, J. A.; Ghosh, S. s.; Parkes, D. G.; Tsakmaki, A.; Gronlund, R. V.; Pedersen, P. J.; Maggs, D.; Rajagopalan, H.; Bewick, G. A.
10.1101/822122 — physiology — Posted on 2020-12-10
2775 The role of mechanical interactions in EMT
Murphy, R. J.; Buenzli, P. R.; Tambyah, T. A.; Thompson, E. W.; Hugo, H. J.; Baker, R. E.; Simpson, M. J.
10.1101/2020.12.09.418434 — biophysics — Posted on 2020-12-10
2777 The biophysical basis of protein domain compatibility in ion channels
Coyote-Maestas, W.; Nedrud, D.; Suma, A.; He, Y.; Matreyek, K. A.; Fowler, D. M.; Carnevale, V.; Myers, C. L.; Schmidt, D.
10.1101/2020.12.09.418442 — biophysics — Posted on 2020-12-10
2780 CytoGLMM: Conditional Differential Analysis for Flow and Mass Cytometry Experiments
Seiler, C.; Ferreira, A.-M.; Kronstad, L. M.; Simpson, L. J.; Le Gars, M.; Vendrame, E.; Blish, C. A.; Holmes, S.
10.1101/2020.12.09.417584 — bioinformatics — Posted on 2020-12-10
2781 Clean and folded: optimized production of high quality recombinant human interferon-{lambda}1
Shaldzhyan, A.; Yolshin, N.; Zabrodskaya, Y.; Kudling, T.; Lozhkov, A.; Plotnikova, M.; Ramsay, E.; Taraskin, A.; Nekrasov, P.; Grudinin, M.; Vasin, A.
10.1101/2020.12.09.417527 — bioengineering — Posted on 2020-12-10
2787 Life-history dynamics: damping time, demographic dispersion and generation time
Jiang, S.; Jaggi, H.; Zuo, W.; Oli, M. K.; Gaillard, J.-M.; Tuljapurkar, S. D.
10.1101/2020.12.09.417261 — ecology — Posted on 2020-12-10
2790 Loss of p32 triggers energy deficiency and impairs goblet cell differentiation in ulcerative colitis
Sünderhauf, A.; Hicken, M.; Schlichting, H.; Skibbe, K.; Ragab, M.; Raschdorf, A.; Hirose, M.; Schäffler, H.; Bokemeyer, A.; Bettenworth, D.; Savitt, A. G.; Perner, S.; Ibrahim, S.; Peerschke, E. I.; Ghebrehiwet, B.; Derer, S.; Sina, C.
10.1101/2020.12.09.417915 — molecular biology — Posted on 2020-12-10
2792 NeutrobodyPlex - Nanobodies to monitor a SARS-CoV-2 neutralizing immune response
Wagner, T. R.; Kaiser, P. D.; Gramlich, M.; Ostertag, E.; Ruetalo, N.; Junker, D.; Haering, J.; Traenkle, B.; Becker, M.; Dulovic, A.; Schweizer, H.; Nueske, S.; Scholz, A.; Zeck, A.; Schenke-Layland, K.; Nelde, A.; Strengert, M.; Walz, J. S.; Zocher, G.; Stehle, T.; Schindler, M.; Schneiderhan-Marra, N.; Rothbauer, U.
10.1101/2020.09.22.308338 — immunology — Posted on 2020-12-10
2793 Non-permissive SARS-CoV-2 infection in human neurospheres
Pedrosa, C. d. S. G.; Goto-Silva, L.; Temerozo, J. R.; Gomes, I. C.; Souza, L. R. Q.; Vitoria, G.; Ornelas, I. M.; Karmirian, K.; Mendes, M. A.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Soares, V. C.; Dias, S. d. S. G.; Salerno, J. A.; Puig-Pijuan, T.; Oliveira, J. T.; Aragao, L. G. H.; Torquato, T. C. Q.; Verissimo, C.; Biagi, D.; Cruvinel, E. M.; Dariolli, R.; Furtado, D. R.; Borges, H. L.; Bozza, P. T.; Rehen, S.; Souza, T. M. L.; Guimaraes, M. Z. P.
10.1101/2020.09.11.293951 — neuroscience — Posted on 2020-12-10
2796 Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings
Westhaus, S.; Widera, M.; Rabenau, H.; Hoehl, S.; Bojkova, D.; Cinatl, J.; Ciesek, S.
10.1101/2020.09.11.292581 — microbiology — Posted on 2020-12-10
2797 Spatial multi-omic map of human myocardial infarction
Kuppe, C.; Ramirez Flores, R. O.; Li, Z.; Hannani, M. T.; Tanevski, J.; Halder, M.; Cheng, M.; Ziegler, S.; Zhang, X.; Priester, F.; Kaesler, N.; Xu, Y.; Hoogenboezem, R.; Bindels, E.; Schneider-Kramann, R.; Milting, H.; Gesteira Costa Filho, I.; Saez Rodriguez, J.; Kramann, R.
10.1101/2020.12.08.411686 — systems biology — Posted on 2020-12-10
2798 Robust integrated intracellular organization of the human iPS cell: where, how much, and how variable?
Viana, M. P.; Chen, J.; Knijnenburg, T. A.; Vasan, R.; Yan, C.; Arakaki, J. E.; Bailey, M.; Berry, B.; Borensztejn, A.; Brown, J. M.; Carlson, S.; Cass, J. A.; Chaudhuri, B.; Cordes Metzler, K. R.; Coston, M. E.; Crabtree, Z. J.; Davidson, S.; DeLizo, C. M.; Dhaka, S.; Dinh, S. Q.; Do, T. P.; Domingus, J.; Donovan-Maiye, R. M.; Foster, T. J.; Frick, C. L.; Fujioka, G.; Fuqua, M. A.; Gehring, J. L.; Gerbin, K. A.; Grancharova, T.; Gregor, B. W.; Harrylock, L.; Haupt, A.; Hendershott, M. C.; Hookway, C.; Horwitz, A. R.; Hughes, C.; Isaac, E. J.; Johnson, G. R.; Kim, B.; Leonard, A. N.; Leung, W.
10.1101/2020.12.08.415562 — cell biology — Posted on 2020-12-10
2801 Unbiased antimicrobial resistance detection from clinical bacterial isolates using proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Schneider, A.; Lasch, P.; Joerg, D.
10.1101/2020.11.17.386540 — microbiology — Posted on 2020-12-10
2803 Detection of cross-frequency coupling between brain areas: an extension of phase-linearity measurement.
Sorrentino, P.; Ambrosanio, M.; Rucco, R.; Cabral, J.; Gollo, L. L.; Breakspeare, M.; Baselice, F.
10.1101/2020.11.25.398628 — neuroscience — Posted on 2020-12-10
2805 Genetic toolkit for sociality predicts castes across the spectrum of social complexity in wasps
Wyatt, C. D. R.; Bentley, M.; Udall, D.; Brock, R. E.; Taylor, B. A.; Bell, E.; Leadbeater, E.; Sumner, S.
10.1101/2020.12.08.407056 — evolutionary biology — Posted on 2020-12-10
2807 ICA-based Denoising Strategies in Breath-Hold Induced Cerebrovascular Reactivity Mapping with Multi Echo BOLD fMRI
Moia, S.; Termenon, M.; Urunuela, E.; Chen, G.; Stickland, R. C.; Bright, M. G.; Caballero Gaudes, C.
10.1101/2020.08.18.256479 — neuroscience — Posted on 2020-12-10
2809 A first assessment of the distribution and abundance of large pelagic species at Cocos Ridge seamounts (Eastern Tropical Pacific) using drifting pelagic baited remote cameras
Cambra, M.; Lara-Lizardi, F.; Penaherrera, C.; Hearn, A.; Ketchum, J. T.; Zarate, P.; Chacon, C.; Suarez-Moncada, J.; Herrera, E.; Espinoza, M.
10.1101/2020.12.09.417493 — ecology — Posted on 2020-12-09
2811 EEG in Motion: Using an Oddball Task to Explore Motor Interference in Active Skateboarding
Robles, D.; Kuziek, J. W. P.; Wlasitz, N. A.; Bartlett, N. T.; Hurd, P. L.; Mathewson, K. E.
10.1101/2020.06.08.136960 — neuroscience — Posted on 2020-12-09
2812 A nanodomain anchored-scaffolding complex is required for PI4Kα function and localization in plants
Noack, L. C.; Bayle, V.; Armengot, L.; Rozier, F.; Mamode-Cassim, A.; Stevens, F. D.; Caillaud, M.-C.; Munnik, T.; Mongrand, S.; Jaillais, Y.
10.1101/2020.12.08.415711 — plant biology — Posted on 2020-12-09
2817 Selection on ancient variations drives the adaptive radiation of Metrosideros across the Hawaiian archipelago
Choi, J. Y.; Dai, X.; Peng, J. Z.; Rughani, P.; Hickey, S.; Harrington, E.; Juul, S.; Ayroles, J.; Purugganan, M.; Stacy, E.
10.1101/2020.11.03.354068 — evolutionary biology — Posted on 2020-12-09
2819 Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation
Lioy, V.; Lorenzi, J.-N.; Najah, S.; Poinsignon, T.; Leh, H.; Saulnier, C.; Aigle, B.; Lautru, S.; Thibessard, A.; Lespinet, O.; Leblond, P.; Jaszczyszyn, Y.; Gorrichon, K.; Varoquaux, N.; Junier, I.; Boccard, F.; Pernodet, J.-L.; Bury-Mone, S. G.
10.1101/2020.12.09.415976 — microbiology — Posted on 2020-12-09
2822 Metabolic potential of uncultured Antarctic soil bacteria revealed through long-read metagenomic sequencing
Waschulin, V.; Borsetto, C.; James, R. S.; Newsham, K. K.; Donadio, S.; Corre, C.; Wellington, E. M.
10.1101/2020.12.09.416412 — microbiology — Posted on 2020-12-09
2825 Cross-Platform Omics Prediction procedure enables precision medicine in patients with stage-III melanoma
Wang, K. Y.; Pupo, G. M.; Tembe, V.; Patrick, E.; Strbenac, D.; Schramm, S.-J.; Thompson, J. F.; Scolyer, R. A.; Mueller, S.; Tarr, G.; Mann, G. J.; Yang, J. Y.
10.1101/2020.12.09.415927 — bioinformatics — Posted on 2020-12-09
2827 Evaluation of optically tailored fluorescent silicon quantum dots for bioimaging of the tear film
Sarwat, S.; Stapleton, F.; Willcox, M. D. P.; O'Mara, P.; Tilley, R.; Gooding, J.; Roy, M.
10.1101/2020.12.09.411876 — biochemistry — Posted on 2020-12-09
2828 Limitations of DNA barcoding in determining the origin of smuggled seahorses and pipefishes
Serite, C. P.; Ntshudisane, O. K.; Swart, E.; Simbine, L.; Jaime, G.; Teske, P. R.
10.1101/2020.12.09.417998 — genetics — Posted on 2020-12-09
2830 UbiB proteins regulate cellular CoQ distribution
Kemmerer, Z. A.; Robinson, K. P.; Schmitz, J. M.; Paulson, B. R.; Jochem, A.; Hutchins, P. D.; Coon, J. J.; Pagliarini, D. J.
10.1101/2020.12.09.418202 — cell biology — Posted on 2020-12-09
2831 The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike
Guo, C.; Tsai, S. J.; Ai, Y.; Li, M.; Pekosz, A.; Cox, A.; Atai, N.; Gould, S.
10.1101/2020.12.08.417022 — cell biology — Posted on 2020-12-09
2832 Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response
Bidgood, S. R.; Novy, K.; Collopy, A.; Albrecht, D.; Krause, M.; Burden, J. J.; Wollscheid, B.; Mercer, J.
10.1101/2020.12.09.418319 — microbiology — Posted on 2020-12-09
2833 The tubovesicular network in Plasmodium vivax liver-stage hypnozoites and schizonts associates with host aquaporin 3
Sylvester, K.; Maher, S. P.; Posfai, D.; Tran, M. K.; Crawford, M. C.; Vantaux, A.; Witkowski, B.; Kyle, D. E.; Derbyshire, E. R.
10.1101/2020.12.09.417949 — microbiology — Posted on 2020-12-09
2834 A plastid antiporter as a bioindicator of Thalassiosira pseudonana resilience
Valenzuela, J. J.; Ashworth, J.; Cusick, A.; Abbriano, R.; Armbrust, E. V.; Hildebrand, M.; Orellana, M. V.; Baliga, N. S.
10.1101/2020.12.09.418384 — systems biology — Posted on 2020-12-09
2836 Allele Mining in Diverse Accessions of Urochloa and Megathyrsus spp. Tropical Grasses to Improve Forage Quality and Reduce Environmental Impact
Hanley, S. J.; Pellny, T. K.; de Vega, J. J.; Castiblanco, V.; Arango, J.; Eastmond, P. J.; Heslop-Harrison, J. S.; Mitchell, R. A. C.
10.1101/2020.12.09.418087 — plant biology — Posted on 2020-12-09
2837 Genome-wide CRISPR and small-molecule screens uncover targetable dependencies in ATRT
Merk, D. J.; Hirsch, S.; Tsiami, F.; Walter, B.; Haeusser, L. A.; Babaei, S.; Admar, J.; Casadei, N.; Roggia, C.; Spohn, M.; Schittenhelm, J.; Singer, S.; Schueller, U.; Piccioni, F.; Persky, N. S.; Root, D. E.; Claassen, M.; Tatagiba, M.; Tabatabai, G.
10.1101/2020.12.09.417378 — cancer biology — Posted on 2020-12-09
2840 Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies
Armstrong, L.; Lange, S. M.; de Cesare, V.; Matthews, S. P.; Nirujogi, R. S.; Cole, I.; Hope, A.; Cunningham, F.; Toth, R.; Mukherjee, R.; Bojkova, D.; Gruber, F.; Gray, D.; Wyatt, P. G.; Cinatl, J.; Dikic, I.; Davies, P.; Kulathu, Y.
10.1101/2020.12.09.417741 — biochemistry — Posted on 2020-12-09
2841 Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
Lopera Maya, E. A.; Kurilshikov, A.; van der Graaf, A.; Hu, S.; Andreu-Sanchez, S.; Chen, L.; Vich Villa, A.; Gacesa, R.; Sinha, T.; Collij, V.; Klassen, M.; Bolte, L. A.; Brandao Gois, M. F.; Neerincx, P. B. T.; Swertz, M. A.; Lifelines Cohort Study, ; Harmsen, H. J. M.; Wijmenga, C.; Fu, J.; Weersma, R. K.; Zhernakova, A.; Sanna, S.
10.1101/2020.12.09.417642 — genetics — Posted on 2020-12-09
2843 Paternal hypoxia exposure primes offspring for increased hypoxia resistance
Ragsdale, A.; Ortega-Recalde, O.; Dutoit, L.; Besson, A. A.; Chia, J. H. Z.; King, T.; Nakagawa, S.; Hickey, A.; Gemmell, N.; Hore, T.; Johnson, S.
10.1101/2020.12.09.416727 — evolutionary biology — Posted on 2020-12-09
2845 Kaiso regulates DNA methylation homeostasis
Kaplun, D.; Filonova, G.; Lobanova, Y.; Mazur, A.; Zhenilo, S.
10.1101/2020.12.09.417576 — molecular biology — Posted on 2020-12-09
2846 Protease-mediated processing of Argonaute proteins controls small RNA association
Gudipati, R. K.; Braun, K.; Gypas, F.; Hess, D.; Schreier, J.; Carl, S. H.; Ketting, R.; Grosshans, H.
10.1101/2020.12.09.417253 — molecular biology — Posted on 2020-12-09
2847 Global query on bacterial sirtuin CobB interactants reveals crosstalk with PRPP synthase Prs
Walter, B. M.; Morcinek-Orlowska, J.; Szulc, A.; Lovering, A. L.; Banzhaf, M.; Glinkowska, M. K.
10.1101/2020.12.09.417477 — molecular biology — Posted on 2020-12-09
2848 TRIM28 regulates Kaiso SUMOylation
Filonova, G.; Lobanova, Y.; Kaplun, D.; Zhenilo, S.
10.1101/2020.12.09.418111 — molecular biology — Posted on 2020-12-09
2849 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
Pras, A.; Houben, B.; Aprile, F. A.; Seinstra, R.; Gallardo, R.; Janssen, L.; Hogewerf, W.; De Vleeschouwer, M.; Mata-Cabana, A.; Koopman, M.; Stroo, E.; De Vries, M.; Edwards, S. L.; Vendruscolo, M.; Falsone, F.; Rousseau, F.; Schymkowitz, J.; Nollen, E. A. A.
10.1101/2020.12.09.417709 — molecular biology — Posted on 2020-12-09
2852 A sinusoidal transform of the visual field in cortical area V2
Sedigh-Sarvestani, M.; Lee, K.-S.; Satterfield, R.; Shultz, N.; Fitzpatrick, D.
10.1101/2020.12.08.416651 — neuroscience — Posted on 2020-12-09
2855 Removal of KCNQ2 from Parvalbumin-expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine
Dunbar, C.; Jing, J.; Sonesra, A.; Park, S.; Soh, H.; Lee, M.; Tzingounis, A.; Cooper, E.; Jiang, X.; Maheshwari, A.
10.1101/2020.12.09.417295 — neuroscience — Posted on 2020-12-09
2857 Hexose fluxes, mediated by vacuolar SWEET transporters, are important for xylem development in the inflorescence stem of Arabidopsis thaliana.
Aubry, E.; Hoffmann, B.; Vilaine, F.; Gilard, F.; Klemens, P. A. W.; Guerard, F.; Gakiere, B.; Neuhaus, H. E.; Bellini, C.; Dinant, S.; Le Hir, R.
10.1101/2020.12.09.417345 — plant biology — Posted on 2020-12-09
2859 Genomic insights on DNase production in Streptococcus agalactiae ST17 and ST19 strains
Silvestre, I.; Nunes, A.; Borges, V.; Isidro, J.; Silva, C.; Vieira, L.; Gomes, J. P.; Borrego, M. J.
10.1101/2020.12.09.418327 — genomics — Posted on 2020-12-09
2860 Intra-host variability in global SARS-CoV-2 genomes as signatures of RNA editing: implications in viral and host response outcomes
Pathak, A. K.; Fatihi, S.; Abbas, T.; Uppili, B.; Mishra, G. P.; Ghosh, A.; Banu, S.; Bhoyar, R. C.; Jain, A.; Divakar, M. K.; Imran, M.; Faruq, M.; Sowpati, D. T.; Raghav, S. K.; Thukral, L.; Mukerji, M.
10.1101/2020.12.09.417519 — genomics — Posted on 2020-12-09
2866 Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development
Szafran, M. J.; Malecki, T.; Strzalka, A.; Pawlikiewicz, K.; Dulawa, J.; Zarek, A.; Kois-Ostrowska, A.; Findlay, K.; Le, T. B. K.; Jakimowicz, D.
10.1101/2020.12.09.403915 — microbiology — Posted on 2020-12-09
2867 Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature
Brydges, C. R.; Fiehn, O.; Mayberg, H. S.; Schreiber, H.; Mahmoudian Dehkordi, S.; Bhattacharyya, S.; Cha, J.; Choi, K. S.; Craighead, W. E.; Krishnan, R. R.; Rush, A. J.; Dunlop, B. W.; Kaddurah-Daouk, R.
10.1101/2020.12.08.388942 — neuroscience — Posted on 2020-12-09
2868 The effects of multi-echo fMRI combination and rapid T2*-mapping on offline and real-time BOLD sensitivity
Heunis, S.; Breeuwer, M.; Caballero-Gaudes, C.; Hellrung, L.; Huijbers, W.; Jansen, J. F.; Lamerichs, R.; Zinger, S.; Aldenkamp, A. P.
10.1101/2020.12.08.416768 — neuroscience — Posted on 2020-12-09
2869 Fractional response analysis reveals logarithmic cytokine responses in cellular populations
Nienałtowski, K.; Rigby, R.; Walczak, J.; Zakrzewska, K. E.; Rehwinkel, J.; Komorowski, M.
10.1101/2020.12.08.413468 — systems biology — Posted on 2020-12-09
2871 Highly multiplexed quantitative phosphosite assay for biology and preclinical studies
Keshishian, H.; McDonald, E. R.; Melanson, R.; Porter, D. A.; Mundth, F.; Krug, K.; Wallace, L.; Forestier, D.; Rabasha, B.; Marlow, S. E.; Jane-Valbuena, J.; Todres, E.; Specht, H.; Golji, J.; Kuhn, E.; Burgess, M.; MacMullan, M.; Satpathy, S.; Mani, D. R.; Gillette, M.; Clauser, K.; Rejtar, T.; Wang, K.; Garraway, L. A.; Sellers, W. R.; Carr, S. A.
10.1101/2020.12.08.415281 — cancer biology — Posted on 2020-12-09
2873 Biologically informed deep neural network for prostate cancer classification and discovery
Elmarakeby, H.; Hwang, J.; Liu, D.; AlDubayan, S. H.; Salari, K.; Richter, C.; Arnoff, T.; Park, J.; Hahn, W. H.; Van Allen, E.
10.1101/2020.12.08.416446 — bioinformatics — Posted on 2020-12-09
2875 Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE
Nagae, T.; Unno, M.; Koizumi, T.; Miyanoiri, Y.; Fujisawa, T.; Masui, K.; Kamo, T.; Wada, K.; Eki, T.; Ito, Y.; Hirose, Y.; Mishima, M.
10.1101/2020.12.08.414581 — biochemistry — Posted on 2020-12-09
2878 Hyperactivation of L-lactate oxidase by liquid-liquid phase separation
Ura, T.; Kagawa, A.; Yagi, H.; Tochio, N.; Kigawa, T.; Mikawa, T.; Shiraki, K.
10.1101/2020.12.08.416958 — biochemistry — Posted on 2020-12-09
2884 Mysterious disappearances of a large mammal in Neotropical forests
Fragoso, J. M. V.; Antunes, A. P.; Altrichter, M.; Constantino, P. d. A. L.; Zapata-Rios, G.; Camino, M.; de thoisy, B.; Wallace, R. B.; El Bizri, H.; Morcatty, T. Q.; Mayor, P.; Richard-Hansen, C.; Hallett, M. T.; Reyna-Hurtado, R.; Beck, H.; de Bustos, S.; Bodmer, R. E.; Keuroghlian, A.; Nava, A.; Montenegro, O. L.; Painkow Neto, E.; Desbiez, A. L. J.; Silvius, K. M.
10.1101/2020.12.08.416552 — ecology — Posted on 2020-12-09
2885 Global Age-Specific Patterns of Cyclic Gene Expression Revealed by Tunicate Transcriptome Atlas
Voskoboynik, Y.; Glina, A.; Kowarsky, M.; Anselmi, C.; Neff, N. F.; Ishizuka, K. J.; Palmeri, K. J.; Rosental, B.; Gordon, T.; Quake, S. R.; Weissman, I. L.; Ben-Shlomo, R.; Sahoo, D.; Voskoboynik, A.
10.1101/2020.12.08.417055 — developmental biology — Posted on 2020-12-09
2886 Unusual Features of the Membrane Kinome of Trypanosoma brucei
Jensen, B. C.; Vaney, P.; Flaspohler, J.; Coppens, I.; Parsons, M.
10.1101/2020.12.08.416529 — molecular biology — Posted on 2020-12-09
2890 Mouse retinal specializations reflect knowledge of natural environment statistics
Qiu, Y.; Zhao, Z.; Klindt, D.; Kautzky, M.; Szatko, K. P.; Schaeffel, F.; Rifai, K.; Franke, K.; Busse, L.; Euler, T.
10.1101/2020.12.08.416172 — neuroscience — Posted on 2020-12-09
2893 Cytoklepty in the plankton: a host strategy to optimize the bioenergetic machinery of endosymbiotic algae
Uwizeye, C.; Mars Brisbin, M.; Gallet, B.; Chevalier, F.; LeKieffre, C.; Schieber, N. L.; Falconet, D.; Wangpraseurt, D.; Schertel, L.; Stryhanyuk, H.; Musat, N.; Mitarai, S.; Schwab, Y.; Finazzi, G.; Decelle, J.
10.1101/2020.12.08.416644 — physiology — Posted on 2020-12-09
2894 Data-informed discovery of hydrolytic nanozymes
Li, S.; Zhou, Z.; Tie, Z.; Wang, B.; Ye, M.; Du, L.; Cui, R.; Liu, W.; Wan, C.; Liu, Q.; Zhao, S.; Wang, Q.; Zhang, Y.; Zhang, S.; Zhang, H.; Du, Y.; Wei, H.
10.1101/2020.12.08.416305 — biophysics — Posted on 2020-12-09
2895 DIAproteomics: A multi-functional data analysis pipeline for data-independent-acquisition proteomics and peptidomics
Bichmann, L.; Gupta, S.; Rosenberger, G.; Kuchenbecker, L.; Sachsenberg, T.; Alka, O.; Pfeuffer, J.; Kohlbacher, O.; Rost, H.
10.1101/2020.12.08.415844 — bioinformatics — Posted on 2020-12-09
2896 Quantitative 3D Imaging of the Cranial Microvascular Environment at Single-Cell Resolution
Rindone, A.; Liu, X.; Farhat, S.; Perdomo-Pantoja, A.; Witham, T.; Coutu, D.; Wan, M.; Grayson, W.
10.1101/2020.12.08.417014 — bioengineering — Posted on 2020-12-09
2898 Transcriptomics and methylomics study on the effect of iodine-containing drug FS-1 on Escherichia coli ATCC BAA-196
Korotetskiy, I. S.; Jumagaziyeva, A. B.; Shilov, S. V.; Kuznetsova, T. V.; Myrzabayeva, A. N.; Iskakbayeva, Z. A.; Ilin, A. I.; Joubert, M.; Taukobong, S.; Reva, O. N.
10.1101/2020.05.15.097816 — genomics — Posted on 2020-12-09
2899 The great tit HapMap project: a continental-scale analysis of genomic variation in a songbird
Spurgin, L. G.; Bosse, M.; Adriaensen, F.; Albayrak, T.; Barboutis, C.; Belda, E.; Bushuev, A.; Cecere, J.; Charmantier, A.; Cichon, M.; Dingemanse, N. J.; Doligez, B.; Eeva, T.; Erikstad, K. E.; Federov, V.; Griggio, M.; Heylen, D.; Hille, S.; Hinde, C.; Ivankina, E.; Laine, V. N.; Kempenaers, B.; Kerimov, A.; Krist, M.; Kvist, L.; Mänd, R.; Matthysen, E.; Nager, R.; Nikolov, B.; Norte, C.; Orell, M.; Ouyang, J.; Petrova-Dinkova, G.; Richner, H.; Rubolini, D.; Slagsvold, T.; Tilgar, V.; Török, J.; Tschirren, B.; Vagasi, C. I.; Yuta, T.; Groenen, M. A. M.; Visser, M. E.; van Oers, K.; Sheld
10.1101/561399 — evolutionary biology — Posted on 2020-12-09
2904 High-throughput Single-cell CNV Detection Reveals Clonal Evolution During Hepatocellular Carcinoma Recurrence
Wu, L.; Wang, Y.; Jiang, M.; Zhou, B.; Sun, Y.; Zhou, K.; Xie, J.; Zhong, Y.; Zhao, Z.; Dean, M.; Hou, Y.; Liu, S.
10.1101/2020.12.09.417626 — cell biology — Posted on 2020-12-09
2905 A Machine Learning Approach Towards Standardizing Microscopic Agglutination Test for Diagnosis of Leptospirosis
Oyamada, Y.; Ozuru, R.; Masuzawa, T.; Miyahara, S.; Nikaido, Y.; Obata, F.; Saito, M.; Villanueva, S. Y. A. M.; Fujii, J.
10.1101/2020.12.08.410712 — microbiology — Posted on 2020-12-09
2906 Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells
Spalinger, M. R.; Hai, R.; Li, J.; Santos, A. N.; Nordgren, T. M.; Tremblay, M. L.; Eckmann, L.; Hanson, E.; Scharl, M.; Wu, X.; Boland, B. S.; McCole, D. F.
10.1101/2020.12.09.416586 — microbiology — Posted on 2020-12-09
2907 Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study
Gabitzsch, E.; Safrit, J. T.; Verma, M.; Rice, A.; Sieling, P.; Zakin, L.; Shin, A.; Morimoto, B.; Adisetiyo, H.; Wong, R.; Bezawada, A.; Dinkins, K.; Balint, J.; Peykov, V.; Garban, H.; Liu, P.; Bacon, A.; Drew, J.; Spilman, P.; Sender, L.; Rabizadeh, S.; Niazi, K.; Soon-Shiong, P.
10.1101/2020.12.08.416297 — immunology — Posted on 2020-12-09
2908 Persistent Cellular Immunity to SARS-CoV-2 Infection
Breton, G.; Mendoza, P.; Hagglof, T.; Oliveira, T. Y.; Schaefer-Babajew, D.; Gaebler, C.; Turroja, M.; Hurley, A.; Caskey, M.; Nussenzweig, M. C.
10.1101/2020.12.08.416636 — immunology — Posted on 2020-12-09
2909 Memory-like B cells emerging from germinal centres recycle through the subcapsular sinus
Zhang, Y.; Garcia-Ibanez, L.; Ulbricht, C.; Lok, L. S. C.; Dennison, T. W.; Ferdinand, J. R.; Mueller-Winkler, J.; Burnett, C. J. M.; Yam-Puc, J. C.; Zhang, L.; Brown, G.; Tybulewicz, V.; Rot, A.; Hauser, A. E.; Clatworthy, M. R.; Toellner, K.-M.
10.1101/2020.12.08.415828 — immunology — Posted on 2020-12-09
2910 Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases
Tarke, A.; Sidney, J.; Kidd, C. K.; Dan, J. M.; Ramirez, S. I.; Yu, E. D.; Mateus, J.; da Silva Antunes, R.; Moore, E.; Rubiro, P.; Methot, N.; Phillips, E. J.; Mallal, S.; Frazier, A.; Rawlings, S.; Greenbaum, J. A.; Peters, B.; Smith, D. M.; Crotty, S.; Weiskopf, D.; Grifoni, A.; Sette, A.
10.1101/2020.12.08.416750 — immunology — Posted on 2020-12-09
2911 Overt visual attention and value computation in complex risky choice
Fan, X.; Elsey, J.; Wyngaard, A.; Yang, Y.-P.; Sampson, A.; Emeric, E. E.; Glickman, M.; Usher, M.; Levy, D.; Stuphorn, V.; Niebur, E.
10.1101/2020.12.08.416313 — neuroscience — Posted on 2020-12-09
2913 A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection
Hulse, B. K.; Haberkern, H.; Franconville, R.; Turner-Evans, D. B.; Takemura, S.-y.; Wolff, T.; Noorman, M.; Dreher, M.; Dan, C.; Parekh, R.; Hermundstad, A. M.; Rubin, G. M.; Jayaraman, V.
10.1101/2020.12.08.413955 — neuroscience — Posted on 2020-12-09
2914 Ligand-receptor promiscuity enables cellular addressing
Su, C. J.; Murugan, A.; Linton, J. M.; Yeluri, A.; Bois, J.; Klumpe, H.; Antebi, Y. E.; Elowitz, M. B.
10.1101/2020.12.08.412643 — systems biology — Posted on 2020-12-09
2915 Pathway to Validate Gene Function in Key Bioenergy Crop, Sorghum bicolor
Aregawi, K. J.; Shen, J.; Pierroz, G.; Bucheli, C.; Sharma, M.; Dahlberg, J.; Owiti, J. A.; Lemaux, P. G.
10.1101/2020.12.08.416347 — plant biology — Posted on 2020-12-09
2916 Host response to cholestyramine can be mediated by the gut microbiota
Newman, N. K.; Monnier, P. M.; Rodrigues, R. R.; Gurung, M.; Vasquez-Perez, S.; Hioki, K. A.; Greer, R. L.; Brown, K.; Morgun, A.; Shulzhenko, N.
10.1101/2020.12.08.416487 — pharmacology and toxicology — Posted on 2020-12-09
2920 Paper-Thin Multilayer Microfluidic Devices with Integrated Valves
Kim, S.; Dorlhiac, G.; Chaves, R. C.; Zalavadia, M.; Streets, A. M.
10.1101/2020.12.08.416883 — bioengineering — Posted on 2020-12-09
2921 Genomic analyses reveal FoxG as an upstream regulator of wnt1 required for posterior identity specification in planarians
Pascual-Carreras, E.; Marin-Barba, M.; Castillo-Lara, S.; Coronel-Cordoba, P.; Magri, M. S.; Wheeler, G. N.; Abril, J. F.; Gomez-Skarmeta, J. L.; Salo, E.; Adell, T.
10.1101/2020.12.08.416008 — developmental biology — Posted on 2020-12-09
2922 Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
Kanen, J. W.; Luo, Q.; Kandroodi, M. R.; Cardinal, R. N.; Robbins, T. W.; Carhart-Harris, R. L.; den Ouden, H. E.
10.1101/2020.12.04.412189 — neuroscience — Posted on 2020-12-09
2936 Absent expansion of pericentral hepatocytes and altered physiology in Axin2CreERT2 mice
May, S.; Mueller, M.; Livingstone, C. R.; Skalka, G.; Nixon, C.; Hedley, A.; Shaw, R.; Clark, W.; Drake, T. M.; Kiourtis, C.; Rocha, A. S.; Sansom, O. J.; Bird, T. G.
10.1101/2020.12.09.405936 — cell biology — Posted on 2020-12-09
2937 HDLs extract lipophilic drugs from cells
Zheng, A.; Dubuis, G.; Mendes Ferreira, C. S.; Mercier, T.; Decosterd, L.; Widmann, C.
10.1101/2020.12.08.415984 — cell biology — Posted on 2020-12-09
2939 Stool serology: development of a non-invasive immunological method for the detection of Enterovirus-specific antibodies in Congo gorilla faeces
Sereme, Y.; Zarza, S. M.; Medkour, H.; Amona, I.; Fenollar, F.; Akiana, J.; Mezouar, S.; Orain, N.; Vitte, J.; Davoust, B.; Raoult, D.; Mediannikov, O.
10.1101/2020.11.28.402230 — microbiology — Posted on 2020-12-09
2940 Swallowing-related neural oscillation: An intracranial EEG study
Hashimoto, H.; Takahashi, K.; Kameda, S.; Yoshida, F.; Maezawa, H.; Oshino, S.; Tani, N.; Khoo, H. M.; Yanagisawa, T.; Yoshimine, T.; Kishima, H.; Hirata, M.
10.1101/2020.12.05.412783 — neuroscience — Posted on 2020-12-09
2941 Moment-by-moment tracking of naturalistic learning and its underlying hippocampo-cortical interactions
Michelmann, S.; Price, A. R.; Aubrey, B.; Doyle, W. K.; Friedman, D.; Dugan, P.; Devinsky, O.; Devore, S.; Flinker, A.; Hasson, U.; Norman, K. A.
10.1101/2020.12.09.416438 — neuroscience — Posted on 2020-12-09
2942 Loss of choline agonism in the inner ear hair cell nicotinic acetylcholine receptor linked to the α10 subunit
Moglie, M. J.; Marcovich, I.; Corradi, J.; Carpaneto Freixas, A. E.; Gallino, S.; Plazas, P. V.; Bouzat, C.; Lipovsek, M.; Elgoyhen, A. B.
10.1101/2020.11.26.400291 — neuroscience — Posted on 2020-12-09
2944 Communicating Regulatory High Throughput Sequencing Data Using BioCompute Objects
King, C. H. S.; Keeney, J. G.; Guimera, N.; Das, S.; Mazumder, R.; Fochtman, B.; Telawar, S.; Patel, J.; Walderhaug, M. O.; Donaldson, E. F.
10.1101/2020.12.07.415059 — scientific communication and education — Posted on 2020-12-09
2945 Mechanisms underlying neonate specific metabolic effects of volatile anesthetics
Stokes, J.; Freed, A.; Pan, A.; Sun, G. X.; Bornstein, R.; Snell, J.; Park, K. Y.; Morgan, P. G.; Sedensky, M. M.; Johnson, S. C.
10.1101/2020.12.08.415950 — physiology — Posted on 2020-12-09
2946 In situ characterization of the 3D microanatomy of the pancreas and pancreatic cancer at single cell resolution
Kiemen, A. L.; Braxton, A. M.; Grahn, M. P.; Han, K. S.; Mahesh Babu, J.; Reichel, R.; Amoa, F.; Hong, S.-M.; Cornish, T. C.; Thompson, E. D.; Wood, L. D.; Hruban, R. H.; Wu, P.-H.; Wirtz, D.
10.1101/2020.12.08.416909 — cancer biology — Posted on 2020-12-09
2951 Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel metazoan specific complex III assembly factor
Chojnacka, K. J.; Mohanraj, K.; Callegari, S.; Mussulini, B. H. M.; Elanchelyan, P.; Gosk, A.; Banach, T.; Goral, T.; Rehling, P.; Serwa, R. A.; Chacinska, A.
10.1101/2020.12.09.417287 — cell biology — Posted on 2020-12-09
2952 Skeletal muscle mitochondrial dysfunction in mice is linked to bone loss via the bone marrow immune microenvironment.
JINGWEN, T.; Ji Sun, M.; Hyo Kyun, C.; Ho Yeop, L.; Jung Tea, K.; Joon Young, C.; Seul Gi, K.; Dongryeol, R.; Xiangguo, C.; Je-Yong, C.; Masayuki, T.; Takayoshi, S.; Sang-Hee, L.; Minho, S.; Hyon-Seung, Y.
10.1101/2020.12.09.417147 — cell biology — Posted on 2020-12-09
2953 A protease-initiated model of wound detection
O'Connor, J. T.; Stevens, A. C.; Shannon, E. K.; Akbar, F. B.; LaFever, K. S.; Narayanan, N.; Hutson, M. S.; Page-McCaw, A.
10.1101/2020.12.08.415554 — cell biology — Posted on 2020-12-09
2957 Information transfer and recovery for the sense of touch
Huang, C.; Englitz, B.; Reznik, A.; Zeldenrust, F.; Celikel, T.
10.1101/2020.12.08.415729 — neuroscience — Posted on 2020-12-09
2958 A nanodomain anchored-scaffolding complex is required for PI4K? function and localization in plants
Jaillais, Y.; Noack, L. C.; Bayle, V.; Armengot, L.; Rozier, F.; Mamode-Cassim, A.; Stevens, F. D.; Caillaud, M.-C.; Munnik, T.; Mongrand, S.
10.1101/2020.12.08.415711 — plant biology — Posted on 2020-12-09
2959 Universal Spectrum Identifier for mass spectra
Deutsch, E. W.; Perez-Riverol, Y.; Carver, J.; Kawano, S.; Mendoza, L.; Van Den Bossche, T.; Gabriels, R.; Binz, P.-A.; Pullman, B.; Sun, Z.; Shofstahl, J.; Bittremieux, W.; Mak, T.; Klein, J.; Zhu, Y.; Lam, H.; Vizcaino, J. A.; Bandeira, N.
10.1101/2020.12.07.415539 — bioinformatics — Posted on 2020-12-09
2961 3D printed scaffold combined to 2D osteoinductive coatings to repair a critical-size mandibular bone defect
BOUYER, M.; GAROT, C.; MACHILLOT, P.; VOLLAIRE, J.; FITZPATRICK, V.; MORAND, S.; BOUTONNAT, J.; JOSSERAND, V.; BETTEGA, G.; PICART, C.
10.1101/2020.12.08.415778 — bioengineering — Posted on 2020-12-09
2963 Does arsenic contamination affect DNA methylation patterns in a wild bird population? An experimental approach
Laine, V.; Verschuuren, M.; van Oers, K.; Espin, S.; Sanchez-Virosta, P.; Eeva, T.; Ruuskanen, S.
10.1101/2020.12.08.415745 — ecology — Posted on 2020-12-09
2967 Feeding Experimentation Device version 3 (FED3): An open-source home-cage compatible device for measuring food intake and operant behavior
Matikainen-Ankney, B. A.; Earnest, T.; Ali, M.; Casey, E.; Sutton, A.; Legaria, A.; Barclay, K.; Murdaugh, L.; Norris, M.; Chang, Y.-H.; Nguyen, K.; Lin, E.; Reichenbach, A.; Clarke, R.; Stark, R.; Conway, S.; Carvalho, F.; Al-Hasani, R.; McCall, J.; Creed, M.; Cazares, V.; Buczynski, M.; Krashes, M.; Andrews, Z.; Kravitz, A.
10.1101/2020.12.07.408864 — animal behavior and cognition — Posted on 2020-12-09
2971 THE DUAL-TASK COST IS DUE TO NEURAL INTERFERENCES DISRUPTING THE OPTIMAL SPATIO-TEMPORAL DYNAMICS OF THE COMPETING TASKS
Mac-Auliffe, D.; Chatard, B.; Petton, M.; Croize, A.-C.; Sipp, F.; Bontemps, B.; Gannerie, A.; Bertrand, O.; Rheims, S.; Kahane, P.; Lachaux, J.-P.
10.1101/2020.12.07.414953 — neuroscience — Posted on 2020-12-09
2972 Genetic toolkit for sociality predicts castes across the spectrum of social complexity in wasps
Wyatt, C. D. R.; Bentley, M.; Udall, D.; Brock, R. E.; Taylor, B. A.; Bell, E.; Leadbeater, E.; Sumner, S.
10.1101/2020.12.08.407056 — evolutionary biology — Posted on 2020-12-09
2973 Canonical Wnt signaling exerts bidirectional control on choroid plexus epithelial development
Parichha, A.; Suresh, V.; Chatterjee, M.; Khsirsagar, A.; Ben-Reuven, L.; Olender, T.; Taketo, M. M.; Radosevic, V.; Bobic-Rasonja, M.; Trinski, S.; Jovanov Milosevic, N.; Reiner, O.; Tole, S.
10.1101/2020.12.08.415588 — developmental biology — Posted on 2020-12-09
2975 Unbiased antimicrobial resistance detection from clinical bacterial isolates using proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Schneider, A.; Lasch, P.; Joerg, D.
10.1101/2020.11.17.386540 — microbiology — Posted on 2020-12-09
2977 Microglia orchestrate neuronal activity in brain organoids
Fagerlund, I.; Dougalis, A.; Shakirzyanova, A.; Gomez-Budia, M.; Konttinen, H.; Ohtonen, S.; Fazaludeen, F.; Koskuvi, M.; Kuusisto, J.; Hernandez, D.; Pebay, A.; Koistinaho, J.; Lehtonen, S.; Korhonen, P.; Malm, T.
10.1101/2020.12.08.416388 — neuroscience — Posted on 2020-12-09
2982 The dynamics of the improvising brain: a study of musical creativity using jazz improvisation
Da Mota, P. A.; Fernandes, H. M.; Stark, E.; Cabral, J.; Heggli, O. A.; Sousa, N.; Kringelbach, M. L.; Vuust, P.
10.1101/2020.01.29.924415 — neuroscience — Posted on 2020-12-09
2984 Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Kildisiute, G.; Kholosy, W. M.; Young, M. D.; Roberts, K.; Elmentaite, R.; van Hooff, S. R.; Khabirova, E.; Piapi, A.; Thevanesan, C.; Bugallo Blanco, E.; Burke, C.; Mamanova, L.; Lijnzaad, P.; Margaritis, T.; Holstege, F. C. P.; Tas, M. L.; Wijnen, M. H. W. A.; van Noesel, M. M.; del Valle, I.; Barone, G.; van der Linden, R.; Duncan, C.; Anderson, J.; Achermann, J. C.; Haniffa, M.; Teichmann, S. C. P.; Rampling, D.; Sebire, N. J.; He, X.; de Krijger, R. R.; Barker, R. A.; Meyer, K. B.; Bayraktar, O.; Straathof, K.; Molenaar, J. J.; Behjati, S.
10.1101/2020.06.22.164301 — cancer biology — Posted on 2020-12-09
2990 Island songbirds as windows into evolution in small populations
Leroy, T.; Rousselle, M.; Tilak, M.-K.; Caizergues, A.; Scornavacca, C.; Recuerda Carrasco, M.; Fuchs, J.; Illera, J. C.; De Swardt, D. H.; Blanco, G.; Thebaud, C.; Mila, B.; Nabholz, B.
10.1101/2020.04.07.030155 — evolutionary biology — Posted on 2020-12-09
2991 Exploratory neuroimmune profiling identifies CNS-specific alterations in COVID-19 patients with neurological involvement
Song, E.; Bartley, C. M.; Chow, R. D.; Ngo, T.; Jiang, R.; Zamecnik, C. R.; Dandekar, R.; Loudermilk, R.; Dai, Y.; Liu, F.; Hawes, I.; Alvarenga, B. D.; Huynh, T.; McAlpine, L.; Rahman, N.-T.; Geng, B.; Chiarella, J.; Israelow, B.; Vogels, C. B.; Grubaugh, N. D.; Casanovas-Massana, A.; Phinney, B. S.; Salemi, M.; Alexander, J.; Gallego, J. A.; Lencz, T.; Walsh, H.; Lucas, C.; Klein, J.; Mao, T.; Oh, J.; Ring, A.; Spudich, S.; Ko, A.; Kleinstein, S.; DeRisi, J. L.; Iwasaki, A.; Pleasure, S. J.; Wilson, M.; Farhadian, S. F.
10.1101/2020.09.11.293464 — immunology — Posted on 2020-12-09
2992 Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
Boroumand, P.; Prescott, D.; Wong, M.; Shen, J.; Tattoli, I.; Zhou, Y.; Shi, N.; Zhu, L. Y.; Liu, Z.; Li, A.; Mukherjee, T.; Bilan, P. J.; Philpott, D. J.; Girardin, S. E.; Klip, A.
10.1101/2020.12.07.414862 — immunology — Posted on 2020-12-09
2993 Peptide-based GIP receptor inhibition produces limited metabolic improvements in mice whether alone or combined with GLP-1 agonism.
West, J. A.; Ghosh, S. S.; Parkes, D. G.; Tsakmaki, A.; Gronlund, R. V.; Pedersen, P. J.; Maggs, D.; Rajagopalan, H.; Bewick, G. A.; Ghosh, S. s.
10.1101/822122 — physiology — Posted on 2020-12-09
2995 Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity
Giroux, N. S.; Ding, S.; McClain, M. T.; Burke, T. W.; Petzold, E. W.; Chung, H. A.; Palomino, G. R.; Wang, E.; Xi, R.; Bose, S.; Rotstein, T.; Nicholson, B. P.; Chen, T.; Henao, R.; Sempowski, G. D.; Denny, T. N.; Ko, E. R.; Ginsburg, G. S.; Kraft, B. D.; Tsalik, E. L.; Woods, C. W.; Shen, X.
10.1101/2020.12.04.412155 — genomics — Posted on 2020-12-09
2996 CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells
Amraei, R.; Napoleon, M.; Yin, W.; Berrigan, J.; Suder, E.; Zhao, G.; Olejnik, J.; Chandler, K.; Xia, C.; Gummuluru, S.; Muhlberger, E.; Chitalia, V.; Costello, C.; Rahimi, N.
10.1101/2020.06.22.165803 — cell biology — Posted on 2020-12-09
2997 Molecular characterization of projection neuron subtypes in the mouse olfactory bulb
Zeppilli, S.; Ackels, T.; Attey, R.; Klimpert, N.; Ritola, K. D.; Boeing, S.; Crombach, A.; Schaefer, A.; Fleischmann, A.
10.1101/2020.11.30.405571 — neuroscience — Posted on 2020-12-08
2998 Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain
Legault, L.-M.; Doiron, K.; Breton-Larrivee, M.; Langford-Avelar, A.; Lemieux, A.; Caron, M.; Jerome-Majewska, L. A.; Sinnett, D.; McGraw, S.
10.1101/2020.12.07.415208 — developmental biology — Posted on 2020-12-08
3001 Starvation induces shrinkage of the bacterial cytoplasm
Shi, H.; Westfall, C. S.; Kao, J.; Odermatt, P. D.; Cesar, S.; Anderson, S.; Sievert, M.; Moore, J.; Gonzalez, C. G.; Zhang, L.; Elias, J. E.; Chang, F.; Huang, K. C.; Levin, P. A.
10.1101/2020.12.06.413849 — microbiology — Posted on 2020-12-08
3002 Evaluating Specimen Quality and Results from a Community-Wide, Home-Based Respiratory Surveillance Study
Kim, A. E.; Brandstetter, E.; Wilcox, N.; Heimonen, J.; Graham, C.; Han, P. D.; Starita, L. M.; McCulloch, D. J.; Casto, A. M.; Nickerson, D. A.; Van de Loo, M. M.; Mooney, J.; Ilcisin, M.; Fay, K. A.; Lee, J.; Sibley, T. R.; Lyon, V.; Geyer, R. E.; Thompson, M.; Lutz, B. R.; Rieder, M. J.; Bedford, T.; Boeckh, M.; Englund, J. A.; Chu, H.
10.1101/2020.12.07.415653 — microbiology — Posted on 2020-12-08
3005 A Draft Reference Genome for Hirudo verbana, the Medicinal Leech
Paulsen, R. T.; Agany, D. D. M.; Petersen, J.; Davis, C. M.; Ehli, E. A.; Gnimpieba, E.; Burrell, B. D.
10.1101/2020.12.08.416024 — genomics — Posted on 2020-12-08
3006 The spatio-temporal axis for phenotypic change: a comparison of source and translocated Arctic charr populations after 25 generations
Hassve, M. H.; Hagenlund, M.; Ostbye, K.; Häkli, K.; Vogler, T.; Gregersen, F.; Andersen, G. B.; Stegarud, S. O.; Langdal, K.; Waalberg, M. E.; Langevoll, K. C.; Praebel, K.
10.1101/2020.12.08.416073 — evolutionary biology — Posted on 2020-12-08
3011 The context-dependent, combinatorial logic of BMP signaling
Klumpe, H. E.; Langley, M. A.; Linton, J. M.; Su, C. J.; Antebi, Y. E.; Elowitz, M. B.
10.1101/2020.12.08.416503 — systems biology — Posted on 2020-12-08
3012 Correlating the structure and activity of Y. pestis Ail in a bacterial cell envelope
Kent, J. E.; Fujimoto, L. M.; Shn, K.; Singh, C.; Yao, Y.; Park, S.; Opella, S. J.; Plano, G. V.; Marassi, F. M.
10.1101/2020.09.23.310672 — biochemistry — Posted on 2020-12-08
3014 Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain
Legault, L.-M.; Doiron, K.; Breton-Larrivee, M.; Langford-Avelar, A.; Lemieux, A.; Caron, M.; Jerome-Majewska, L. A.; Sinnett, D.; McGraw, S.
10.1101/2020.12.07.415208 — developmental biology — Posted on 2020-12-08
3015 Binding of SARS-CoV-2 spike protein to ACE2 is disabled by thiol-based drugs; evidence from in vitro SARS-CoV-2 infection studies.
Khanna, K.; Raymond, W.; Charbit, A. R.; Jin, J.; Gitlin, I.; Tang, M.; Sperber, H. S.; Franz, S.; Pillai, S.; Simmons, G.; Fahy, J. V.
10.1101/2020.12.08.415505 — microbiology — Posted on 2020-12-08
3017 Selective neuromodulation induced by alpha-based neurofeedback learning: A double-blind randomized study
Grosselin, F.; Breton, A.; Yahia-Cherif, L.; Wang, X.; Spinelli, G.; Hugueville, L.; Fossati, P.; Attal, Y.; Navarro, X.; Chavez, M.; George, N.
10.1101/2020.12.02.406173 — neuroscience — Posted on 2020-12-08
3021 Molecular and physiological responses predict acclimation limits in juvenile brook trout ( Salvelinus fontinalis )
Mackey, T. E.; Hasler, C. T.; Durhack, T.; Jeffrey, J. D.; Macnaughton, C. J.; Ta, K.; Enders, E. C.; Jeffries, K. M.
10.1101/2020.12.07.414821 — physiology — Posted on 2020-12-08
3022 ATRX alteration contributes to tumor growth and immune escape in pleomorphic sarcomas
Darmusey, L.; Perot, G.; Thebault, N.; Le Guellec, S.; Desplat, N.; Gaston, L.; Delespaul, L.; Lesluyes, T.; Darbo, E.; Gomez-Brouchet, A.; Richard, E.; Baud, J.; Leroy, L.; Coindre, J. M.; Blay, J.-Y.; Chibon, F.
10.1101/2020.10.23.352112 — cancer biology — Posted on 2020-12-08
3026 Intrinsic disorder codes for leaps of protein expression
Chuang, C.-N.; Woo, T.-T.; Tsai, S.-Y.; Chen, C.-L.; Li, W.-C.; Liu, H.-C.; Chen, C.-Y.; Hsueh, Y.-P.; Wang, T.-F.
10.1101/2020.12.08.407247 — biochemistry — Posted on 2020-12-08
3028 The human odorant receptor OR10A6 is tuned to the pheromone of the commensal fruit fly Drosophila melanogaster
Frey, T.; Kwadha, C. A.; Wallin, E. A.; Holgersson, E.; Hedenstroem, E.; Bohman, B.; Bengtsson, M.; Becher, P. G.; Krautwurst, D.; Witzgall, P.
10.1101/2020.12.07.414714 — animal behavior and cognition — Posted on 2020-12-08
3030 Flexible multivariate linear mixed models for structured multiple traits
Kim, H.; Farage, G.; Lovell, J. T.; Mckay, J. K.; Juenger, T. E.; Sen, S.
10.1101/2020.03.27.012690 — genetics — Posted on 2020-12-08
3031 Haplotype divergence supports ancient asexuality in the oribatid mite Oppiella nova
Brandt, A.; Tran Van, P.; Bluhm, C.; Anselmetti, Y.; Dumas, Z.; Figuet, E.; Francois, C. M.; Galtier, N.; Heimburger, B.; Jaron, K. S.; Labedan, M.; Maraun, M.; Parker, D. J.; Robinson-Rechavi, M.; Schaefer, I.; Simion, P.; Scheu, S.; Schwander, T.; Bast, J.
10.1101/2020.12.07.414623 — evolutionary biology — Posted on 2020-12-08
3032 A time-lagged association between the gut microbiome, nestling weight and nestling survival in wild great tits
Davidson, G. L.; Somers, S. E.; Wiley, N.; Johnson, C. N.; Reichert, M. S.; Ross, R. P.; Stanton, C.; Quinn, J. L.
10.1101/2020.09.30.320804 — ecology — Posted on 2020-12-08
3034 ATP triggers macropinocytosis that internalizes and is regulated by PANX1
Boyce, A. K.; van der Slagt, E.; Sanchez-Arias, J. C.; Swayne, L. A.
10.1101/2020.11.19.389072 — cell biology — Posted on 2020-12-08
3036 Circular RNA profiling reveals abundant and diverse circRNAs of SARS-CoV-2, SARS-CoV and MERS-CoV origin
Yang, S.; Zhou, H.; Cruz-Cosme, R.; Liu, M.; Niu, X.; Xu, J.; Li, Y.; Xiao, L.; Wang, Q.; Zhu, H.; Tang, Q.
10.1101/2020.12.07.415422 — microbiology — Posted on 2020-12-08
3037 Multiple clones of colistin-resistant Salmonella enterica carrying mcr-1 plasmids in meat products and patients in Northern Thailand
Patchanee, P.; Chokesajjawatee, N.; Santiyanont, P.; Chuammitri, P.; Deeudom, M.; Monteith, W.; Sheppard, S. K.; Pascoe, B.; Prasertee, T.
10.1101/2020.12.08.415869 — microbiology — Posted on 2020-12-08
3041 Characterization of the antimicrobial activity of the cell-penetrating peptide TAT-RasGAP317-326
Georgieva, M.; Heinonen, T.; Vitale, A.; Hargraves, S.; Causevic, S.; Pillonel, T.; Eberl, L.; Widmann, C.; Jacquier, N.
10.1101/2020.10.02.321802 — microbiology — Posted on 2020-12-08
3043 The transcription factor Pdr802 regulates Titan cell formation, quorum sensing, and pathogenicity of Cryptococcus neoformans
Reuwsaat, J. C. V.; Motta, H.; Agustinho, D. P.; Brown, H.; Chang, A. L.; Brent, M. R.; Kmetzsch, L.; Doering, T. L.
10.1101/2020.06.29.179242 — microbiology — Posted on 2020-12-08
3044 Evaluating Specimen Quality and Results from a Community-Wide, Home-Based Respiratory Surveillance Study
Kim, A. E.; Brandstetter, E.; Wilcox, N.; Heimonen, J.; Graham, C.; Han, P. D.; Starita, L. M.; McCulloch, D. J.; Casto, A. M.; Nickerson, D. A.; Van de Loo, M. M.; Mooney, J.; Ilcisin, M.; Fay, K. A.; Lee, J.; Sibley, T. R.; Lyon, V.; Geyer, R. E.; Thompson, M.; Lutz, B. R.; Rieder, M. J.; Bedford, T.; Boeckh, M.; Englund, J. A.; Chu, H.
10.1101/2020.12.07.415653 — microbiology — Posted on 2020-12-08
3045 Commensal Microbiota Regulates Skin Barrier Function And Repair Via Signaling Through The Aryl Hydrocarbon Receptor
Uberoi, A.; Bartow-McKenney, C.; Zheng, Q.; Flowers, L.; Campbell, A.; Knight, S. A. B.; Chan, N.; Wei, M.; Lovins, V.; Bugayev, J.; Horwinski, J.; Bradley, C.; Meyer, J.; Crumrine, D.; Sutter, C. H.; Elias, P.; Mauldin, E.; Sutter, T. R.; Grice, E. A.
10.1101/2020.12.05.413096 — microbiology — Posted on 2020-12-08
3046 Engineered receptor binding domain immunogens elicit pan-coronavirus neutralizing antibodies
Hauser, B. M.; Sangesland, M.; Lam, E. C.; Feldman, J.; Yousif, A. S.; Caradonna, T. M.; Balazs, A. B.; Lingwood, D.; Schmidt, A. G.
10.1101/2020.12.07.415216 — immunology — Posted on 2020-12-08
3050 Reusability and composability in process description maps: RAS-RAF-MEK-ERK signalling
Mazein, A.; Rougny, A.; Karr, J. R.; Saez Rodriguez, J.; Ostaszewski, M.; Schneider, R.
10.1101/2020.12.08.416719 — systems biology — Posted on 2020-12-08
3051 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-12-08
3052 SRF-MYOCD axis is the targetable driver of a well differentiated aggressive subtype of leiomyosarcomas
Darbo, E.; Perot, G.; Darmusey, L.; Le Guellec, S.; Leroy, L.; Gaston, L.; Desplat, N.; Thebault, N.; Merle, C.; Rochaix, P.; Valentin, T.; Ferron, G.; Chevreau, C.; Bui, B.; Stoeckle, E.; Ranchere-Vince, D.; Meeus, P.; Terrier, P.; Piperno-Neumann, S.; Colin, F.; De Pinieux, G.; Duffaud, F.; Coindre, J.-M.; Blay, J.-Y.; Chibon, F.
10.1101/2020.10.23.352336 — cancer biology — Posted on 2020-12-08
3058 Genome-wide association study of pain sensitivity assessed by questionnaire and the cold pressor test
Fontanillas, P.; Kless, A.; 23andMe Research Team, ; Bothmer, J.; Tung, J. Y.
10.1101/837526 — genetics — Posted on 2020-12-08
3060 A holobiont view of island biogeography: unraveling patterns driving the nascent diversification of a Hawaiian spider and its microbial associates
Armstrong, E.; Perez-Lamarque, B.; Bi, K.; Chen, C.; Becking, L. E.; Lim, J. Y.; Linderoth, T.; Krehenwinkel, H.; Gillespie, R.
10.1101/2020.12.07.414961 — evolutionary biology — Posted on 2020-12-08
3065 Dissociation of the intramolecularly cleaved N- and C-terminal fragments of the adhesion G protein-coupled receptor GPR133 (ADGRD1) increases canonical signaling
Frenster, J. D.; Stephan, G.; Ravn-Boess, N.; Bready, D.; Wilcox, J.; Kieslich, B.; Wilde, C.; Sträter, N.; Wiggin, G. R.; Liebscher, I.; Schöneberg, T.; Placantonakis, D. G.
10.1101/2020.12.08.415398 — cell biology — Posted on 2020-12-08
3066 Coordinated post-transcriptional control of oncogene-induced senescence by UNR/CSDE1
Avolio, R.; Ingles Ferrandiz, M.; Ciocia, A.; Bonnin, S.; Ribo Rubio, A.; Gebauer, F.
10.1101/2020.12.08.415794 — molecular biology — Posted on 2020-12-08
3068 Extended in vitro inactivation of SARS-CoV-2 by titanium dioxide surface coating
Mlcochova, P.; Chadha, A.; Hesselhoj, T.; Fraternali, F.; Ramsden, J.; Gupta, R. K.
10.1101/2020.12.08.415018 — microbiology — Posted on 2020-12-08
3069 Editing of the TRIM5 gene decreases the permissiveness of human T lymphocytic cells to HIV-1
Desaulniers, K.; Ortiz, L.; Dufour, C.; Claudel, A.; B. Plourde, M.; Merindol, N.; Berthoux, L.
10.1101/2020.12.07.413708 — microbiology — Posted on 2020-12-08
3070 MRSA emerges through natural transformation
Maree, M.; Nguyen, L. T. T.; Ohniwa, R.; Huang, S.; Higashide, M.; Msadek, T.; Morikawa, K.
10.1101/2020.12.08.415893 — microbiology — Posted on 2020-12-08
3072 Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives
Sa-ngiamsuntorn, K.; Suksatu, A.; Pewkliang, Y.; Thongsri, P.; Kanjanasirirat, P.; Manopwisedjaroen, S.; Charoensutthivarakul, S.; Wongtrakoongate, P.; Pitiporn, S.; Khemawoot, P.; Chutipongtanate, S.; Borwornpinyo, S.; Thitithanyanont, A.; Hongeng, S.
10.1101/2020.12.08.415836 — microbiology — Posted on 2020-12-08
3073 Natural SARS-CoV-2 infections, including virus isolation, among serially tested cats and dogs in households with confirmed human COVID-19 cases in Texas, USA
Hamer, S. A.; Pauvolid-Correa, A.; Zecca, I. B.; Davila, E.; Auckland, L. D.; Roundy, C. M.; Tang, W.; Torchetti, M. K.; Killian, M. L.; Jenkins-Moore, M.; Mozingo, K.; Akpalu, Y.; Ghai, R. R.; Spengler, J. R.; Barton Behravesh, C.; Fischer, R.; Hamer, G. L.
10.1101/2020.12.08.416339 — zoology — Posted on 2020-12-08
3076 NEONATAL THYROXINE ACTIVATION MODIFIES EPIGENETIC PROGRAMMING OF THE LIVER
Fonseca, T. L.; Garcia, T.; Fernandes, G. W.; Nair, T. M.; Bianco, A. C.
10.1101/2020.12.07.414938 — physiology — Posted on 2020-12-08
3083 Accurate neoantigen prediction depends on mutation position relative to patient allele-specific MHC anchor location
Xia, H.; McMichael, J. F.; Supabphol, S.; Richters, M. M.; Basu, A.; Ramirez, C. A.; Puig-Saus, C.; Cotto, K. C.; Hundal, J.; Kiwala, S.; Goedegebuure, S. P.; Johanns, T. M.; Dunn, G. P.; Fehniger, T. A.; Ribas, A.; Miller, C. A.; Gillanders, W. E.; Griffith, O. L.; Griffith, M.
10.1101/2020.12.08.416271 — bioinformatics — Posted on 2020-12-08
3084 Dual site-specific chemoenzymatic antibody fragment conjugation using CRISPR-based hybridoma engineering
Le Gall, C. M.; van der Schoot, J. M.; Ramos-Tomillero, I.; Parlak Khalily, M.; van Dalen, F. J.; Wijfjes, Z.; Smeding, L.; van Dalen, D.; Cammarata, A.; Bonger, K. M.; Figdor, C. G.; Scheeren, F. A.; Verdoes, M.
10.1101/2020.12.08.415182 — biochemistry — Posted on 2020-12-08
3088 Astroglial calcium transfer from endoplasmic reticulum to mitochondria determines synaptic integration
Serrat, R.; Covelo, A.; Kouskoff, V.; Delcasso, S.; Ruiz, A.; Chenouard, N.; Stella, C.; Blancard, C.; Salin, B.; Julio-Kalajzic, F.; Cannich, A.; Massa, F.; Varilh, M.; Deforges, S.; Robin, L.; Destefani, D.; Busquets-Garcia, A.; Gambino, F.; Beyeler, A.; Pouvreau, S.; Marsicano, G.
10.1101/2020.12.08.415620 — neuroscience — Posted on 2020-12-08
3089 Rapid selection response to ethanol in S. eubayanus emulates the domestication process under brewing conditions
Mardones, W.; Villarroel, C. A.; Abarca, V.; Urbina, K.; Pena, T. A.; Molinet, J.; Nespolo, R. F.; Cubillos, F.
10.1101/2020.12.07.415240 — genetics — Posted on 2020-12-08
3090 Protein appetite drives macronutrient-related differences in ventral tegmental area neural activity
Chiacchierini, G.; Naneix, F.; Peters, K. Z.; Apergis-Schoute, J.; Snoeren, E. M.; McCutcheon, J.
10.1101/542340 — neuroscience — Posted on 2020-12-08
3091 hcga: Highly Comparative Graph Analysis for network phenotyping
Peach, R. L.; Arnaudon, A.; Schmidt, J. A.; Palasciano, H.; Bernier, N. R.; Jelfs, K.; Yaliraki, S.; Barahona, M.
10.1101/2020.09.25.312926 — systems biology — Posted on 2020-12-08
3092 Decellularization enables functional analysis of ECM remodeling in planarian regeneration
Sonpho, E.; Mann, F. G.; Levy, M.; Ross, E. J.; Guerrero-Hernandez, C.; Florens, L.; Saraf, A.; Doddihal, V.; Ounjai, P.; Sanchez Alvarado, A.
10.1101/2020.09.11.293936 — developmental biology — Posted on 2020-12-08
3093 Early life nociception is influenced by peripheral growth hormone signaling
Dourson, A. J.; Ford, Z. K.; Green, K. J.; McCrossan, C. E.; Hofmann, M. C.; Hudgins, R. C.; Jankowski, M. P.
10.1101/2020.07.16.206904 — neuroscience — Posted on 2020-12-08
3094 An immersive first-person navigation task for abstract knowledge acquisition
Kuhrt, D.; St. John, N. R.; Bellmund, J. L. S.; Kaplan, R.; Doeller, C. F.
10.1101/2020.07.17.208900 — neuroscience — Posted on 2020-12-08
3095 Aster repulsion drives local ordering in an active system
de-Carvalho, J.; Tlili, S.; Hufnagel, L.; Saunders, T. E.; Telley, I. A.
10.1101/2020.06.04.133579 — biophysics — Posted on 2020-12-08
3097 Sex-biased reduction in reproductive success drives selective constraint on human genes
Gardner, E. J.; Neville, M. D.; Samocha, K. E.; Barclay, K.; Kolk, M.; Niemi, M. E.; Kirov, G.; Martin, H. C.; Hurles, M. E.
10.1101/2020.05.26.116111 — genetics — Posted on 2020-12-08
3098 Developing synergistic drug combinations to restore antibiotic sensitivity in drug-resistant Mycobacterium tuberculosis
Omollo, C. O.; Singh, V.; Kigondu, E.; Wasuna, A.; Agarwal, P.; Moosa, A.; Ioerger, T. R.; Mizrahi, V.; Chibale, K.; Warner, D. F.
10.1101/860288 — microbiology — Posted on 2020-12-08
3107 Representational Dynamics Preceding Conscious Access
Alilovic, J.; van Moorselaar, D.; Graetz, M.; van Gaal, S.; Slagter, H. A.
10.1101/2020.08.30.274019 — neuroscience — Posted on 2020-12-08
3112 Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis
Miguel, V.; Tituana, J.; Herrero, J. I.; Herrero, L.; Serra, D.; Cuevas, P.; Barbas, C.; Rodriguez-Puyol, D.; Marquez-Exposito, L.; Ruiz-Ortega, M.; Castillo, C.; Sheng, X.; Susztak, K.; Ruiz-Canela, M.; Salas-Salvado, J.; Martinez Gonzalez, M. A.; Ortega, S.; Ramos, R.; Lamas, S.
10.1101/2020.02.18.952440 — biochemistry — Posted on 2020-12-08
3113 Quantifying liquid-liquid phase separation property of chromatin under physiological conditions using Hi-MS and Hi-C
Shi, M.; You, K.; Hou, C.; Chen, T.; Liang, Z.; Liu, M.; Wang, J.; Wei, T.; Qin, J.; Chen, Y.; Li, T.; Zhang, M. Q.
10.1101/2020.12.07.415489 — cell biology — Posted on 2020-12-08
3114 The chemotherapeutic drug methotrexate selects for antibiotic resistance
Guthmundsdottir, J. S.; Fredheim, E. G. A.; Koumans, C. I. M.; Hegstad, J.; Tang, P.-C.; Andersson, D. I.; Samuelsen, O.; Johnsen, P. J.
10.1101/2020.11.12.378059 — microbiology — Posted on 2020-12-08
3115 Genes influencing phage host range in Staphylococcus aureus on a species-wide scale
Moller, A. G.; Winston, K.; Ji, S.; Wang, J.; Hargita Davis, M. N.; Solis-Lemus, C. R.; Read, T.
10.1101/2020.07.24.218685 — microbiology — Posted on 2020-12-08
3116 Control of Social Withdrawal of Mice Deficient for the Autism Gene Magel2 by Restoration of Vasopressin-Oxytocin Dialogue in Septum
Borie, A. M.; Dromard, Y.; Dufner, D.; Pollozi, E.; Huzard, D.; Tomboli, C.; Olma, A.; Manning, M.; Colson, P.; Guillon, G.; Muscatelli, F.; Desarmenien, M. G.; Jeanneteau, F.
10.1101/800425 — neuroscience — Posted on 2020-12-08
3120 Concatemeric Broccoli reduces mRNA stability, aggregates and induces p-body formation
Rink, M. R.; Baptista, M. A. P.; Hennig, T.; Whisnant, A. W.; Wolf, N.; Seibel, J.; Dölken, L.; Bosse, J. B.
10.1101/2020.12.07.414458 — microbiology — Posted on 2020-12-07
3124 The relative roles of voice and gesture in early communication development
Burkhardt-Reed, M. M.; Long, H. L.; Bowman, D. D.; Bene, E. R.; Oller, D. K.
10.1101/2020.12.07.415232 — developmental biology — Posted on 2020-12-07
3125 GLI3 Processing by the Primary Cilium Regulates Muscle Stem Cell Entry into GAlert
Brun, C.; Sincennes, M.-C.; Lin, A. Y. T.; Hall, D.; Jarassier, W.; Feige, P.; Ritso, M.; Le Grand, F.; Rudnicki, M. A.
10.1101/2020.12.07.415273 — cell biology — Posted on 2020-12-07
3126 Conservation of the Toxoplasma conoid complex proteome reveals a cryptic conoid in Plasmodium that differentiates between blood- and vector-stage zoites
Koreny, L.; Zeeshan, M.; Barylyuk, K.; Tromer, E. C.; van Hooff, J. J. E.; Brady, D.; Ke, H.; Chelaghma, S.; Ferguson, D. J. P.; Eme, L.; Tewari, R.; Waller, R. F.
10.1101/2020.06.26.174284 — cell biology — Posted on 2020-12-07
3127 mSWI/SNF promotes polycomb repression both directly and through genome-wide redistribution
Weber, C. M.; Hafner, A.; Braun, S. M. G.; Kirkland, J. G.; Stanton, B. Z.; Boettiger, A. N.; Crabtree, G. R.
10.1101/2020.01.29.925586 — molecular biology — Posted on 2020-12-07
3130 Comparative neurotranscriptomics reveal widespread species differences associated with bonding
Tripp, J. A.; Berrio, A. A.; McGraw, L. A.; Matz, M. V.; Davis, J. K.; Inoue, K.; Thomas, J. W.; Young, L.; Phelps, S. M.
10.1101/2020.12.07.415463 — neuroscience — Posted on 2020-12-07
3131 Atrophy of spared subcortical nuclei relates to worse post-stroke sensorimotor outcomes across 28 cohorts worldwide
Liew, S.-L.; Zavaliangos-Petropulu, A.; Schweighofer, N.; Jahanshad, N.; Lang, C. E.; Lohse, K. R.; Banaj, N.; Barisano, G.; Baugh, L. A.; Bhattacharya, A. K.; Bigjahan, B.; Borich, M. R.; Boyd, L. A.; Brodtmann, A.; Buetefisch, C. M.; Byblow, W. D.; Cassidy, J. M.; Ciullo, V.; Conforto, A. B.; Craddock, R. C.; Dula, A. N.; Egorova, N.; Feng, W.; Fercho, K. A.; Gregory, C. M.; Hanlon, C. A.; Hayward, K. S.; Holguin, J. A.; Hordacre, B.; Hwang, D. H.; Kautz, S. A.; Khlif, M. S.; Kim, B.; Kuceyeski, A.; Liu, J.; Lin, D.; Lotze, M.; Kim, H.; MacIntosh, B. J.; Margetis, J. L.; Mohamed, F. B.; Nord
10.1101/2020.11.04.366856 — neuroscience — Posted on 2020-12-07
3132 Mutated clones driving leukemic transformation are already detectable at the single cell level in CD34-positive cells in the chronic phase of primary myelofibrosis
Parenti, S.; Rontauroli, S.; Carretta, C.; Mallia, S.; Genovese, E.; Chiereghin, C.; Peano, C.; Tavernari, L.; Bianchi, E.; Fantini, S.; Sartini, S.; Romano, O.; Bicciato, S.; Tagliafico, E.; DELLA PORTA, M. G.; MANFREDINI, R.
10.1101/2020.12.07.414177 — cancer biology — Posted on 2020-12-07
3138 Perinatal fentanyl exposure leads to long-lasting impairments in somatosensory circuit function and behavior
Alipio, J.; Haga, C.; Fox, M. E.; Arakawa, K.; Balaji, R.; Cramer, N.; Lobo, M. K.; Keller, A.
10.1101/2020.09.19.304352 — neuroscience — Posted on 2020-12-07
3140 Oxytocinergic modulation of threat-specific amygdala sensitization in humans is critically mediated by serotonergic mechanisms
Liu, C.; Lan, C.; Li, K.; Zhou, F.; Yao, S.; Xu, L.; Yang, N.; Yang, J.; Yong, X.; Ma, Y.; Scheele, D.; Kendrick, K. M.; Becker, B.
10.1101/2020.05.20.105684 — neuroscience — Posted on 2020-12-07
3142 Immunoproteasome deficiency leads to sustained pancreatic injury and delayed recovery from experimental pancreatitis
de Freitas Chama, L. L.; Ebstein, F.; Wiesrecker, B.; Wagh, P. R.; Weiss, F. U.; Junker, H.; Studencka-Turski, M.; Lerch, M. M.; Krueger, E.; Sendler, M.
10.1101/2020.11.17.386482 — physiology — Posted on 2020-12-07
3143 RIOK2 drives glioblastoma cell growth and proliferation by modulating MYC through the RNA-binding protein IMP3
Chen, A. S.; Marquez, J.; Boyd, N. H.; Oh, S.-Y.; Gulbronson, R.; Hamilton, J. A. G.; Legan, E. R.; Read, R.
10.1101/2020.12.07.413385 — cancer biology — Posted on 2020-12-07
3145 A GO catalogue of human DNA-binding transcription factors
Lovering, R. C.; Gaudet, P.; Acencio, M. L.; Ignatchenko, A.; Jolma, A.; Fornes, O.; Kuiper, M.; Kulakovskiy, I. V.; Laegreid, A.; Martin, M. J.; Logie, C.
10.1101/2020.10.28.359232 — bioinformatics — Posted on 2020-12-07
3149 Joint species distributions reveal the combined effects of host plants, abiotic factors and species competition as drivers of community structure in fruit flies
Facon, B.; Hafsi, A.; Charlery, M.; Robin, S.; Massol, F.; Dubart, M.; Chiquet, J.; Frago, E.; Chiroleu, F.; Duyck, P.-F.; Ravigne, V.
10.1101/2020.12.07.414326 — ecology — Posted on 2020-12-07
3150 Light-dependent induction of Edn2 expression and attenuation of retinal pathology by endothelin receptor antagonists in Prominin-1- deficient mice
Kobayashi, Y.; Watanabe, S.; Shirai, M.; Yamashiro, C.; Ogata, T.; Higashijima, F.; Yoshimoto, T.; Hayano, T.; Asai, Y.; Sasai, N.; Kimura, K.
10.1101/2020.12.07.405308 — neuroscience — Posted on 2020-12-07
3151 Transcriptome analysis for the development of cell-type specific labeling to study olfactory circuits
Koldaeva, A.; Zhang, C.; Huang, Y.-P.; Reinert, J. K.; Mizuno, S.; Sugiyama, F.; Takahashi, S.; Soliman, T.; Matsunami, H.; Fukunaga, I.
10.1101/2020.11.30.403865 — neuroscience — Posted on 2020-12-07
3154 Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health
Marabita, F.; James, T.; Karhu, A.; Virtanen, H.; Kettunen, K.; Stenlund, H.; Boulund, F.; Hellström, C.; Neiman, M.; Mills, R.; Perheentupa, T.; Laivuori, H.; Helkkula, P.; Byrne, M.; Jokinen, I.; Honko, H.; Kallonen, A.; Ermes, M.; Similä, H.; Lindholm, M.; Widen, E.; Ripatti, S.; Perälä-Heape, M.; Engstrand, L.; Nilsson, P.; Moritz, T.; Miettinen, T.; Sallinen, R.; Kallioniemi, O.
10.1101/2020.11.11.365387 — systems biology — Posted on 2020-12-07
3155 A novel protein complex that regulates active DNA demethylation in Arabidopsis
Liu, P.; Nie, W.-F.; Xiong, X.; Wang, Y.; Jiang, Y.; Huang, P.; Lin, X.; Qin, G.; Huang, H.; Niu, Q.; Du, J.; Lang, Z.; Lozano-Duran, R.; Zhu, J.-K.
10.1101/2020.02.21.958371 — plant biology — Posted on 2020-12-07
3156 NAD+ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy
Chiao, Y. A.; Chakraborty, A.; Light, C.; Tian, R.; Sadoshima, J.; Shi, X.; Gu, H.; Lee, C. F.
10.1101/2020.07.03.183111 — physiology — Posted on 2020-12-07
3157 Intraspecific variation in thermal tolerance differs between tropical and temperate fishes
Nati, J. J. H.; Svendsen, M. B. S.; Marras, S.; Killen, S. S.; Steffensen, J. F.; McKenzie, D. J.; Domenici, P.
10.1101/2020.12.07.414318 — physiology — Posted on 2020-12-07
3158 Ppard Is Essential in Acceleration of Pancreatic Ductal Adenocarcinoma Development by High-Fat Diet in Mutant Kras Mice
Liu, Y.; Deguchi, Y.; Wei, D.; Moussalli, M. J.; Li, D.; Wang, H.; Valentin, L. A.; Colby, J. K.; Liu, F.; Wang, J.; Zheng, X.; Ji, B.; Yao, J. C.; Zuo, X.; Shureiqi, I.
10.1101/2020.12.04.412320 — cancer biology — Posted on 2020-12-07
3159 Giotto, a toolbox for integrative analysis and visualization of spatial expression data
Dries, R.; Zhu, Q.; Dong, R.; Eng, C.-H. L.; Li, H.; Liu, K.; Fu, Y.; Zhao, T.; Sarkar, A.; Bao, F.; George, R. E.; Pierson, N.; Cai, L.; Yuan, G.-C.
10.1101/701680 — bioinformatics — Posted on 2020-12-07
3162 An Organoid for woven Bone
Akiva, A.; Melke, J.; Ansari, S.; Liv, N.; van der Meijden, R.; van Erp, M.; Zhao, F.; Stout, M.; Nijhuis, W. H.; de Heus, C.; Muniz Ortera, C.; Fermie, J.; Klumperman, J.; Ito, K.; Sommerdijk, N.; Hofmann, S.
10.1101/2020.06.15.152959 — bioengineering — Posted on 2020-12-07
3165 Infertility due to defective sperm flagella caused by an intronic deletion in DNAH17 that perturbs splicing
Noskova, A.; Hiltpold, M.; Janett, F.; Echtermann, T.; Fang, Z.-H.; Sidler, X.; Selige, C.; Hofer, A.; Neuenschwander, S.; Pausch, H.
10.1101/2020.10.16.333344 — genomics — Posted on 2020-12-07
3167 Global elongation and high shape flexibility as an evolutionary hypothesis of accommodating mammalian brains into skulls
Weisbecker, V.; Rowe, T.; Wroe, S.; Macrini, T. E.; Garland, K. L. S.; Travouillon, K. J.; Black, K.; Archer, M.; Hand, S. J.; Berlin, J.; Beck, R. M. D.; Ladeveze, S.; Sharp, A. C.; Mardon, K.; Sherratt, E.
10.1101/2020.12.06.410928 — evolutionary biology — Posted on 2020-12-07
3172 Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain
Legault, L.-M.; Doiron, K.; Breton-Larrivee, M.; Langford-Avelar, A.; Lemieux, A.; Caron, M.; Jerome-Majewska, L. A.; Sinnett, D.; McGraw, S.
10.1101/2020.12.07.415208 — developmental biology — Posted on 2020-12-07
3173 Comparative profiling of N-respirasomes predicts aberrant mitochondrial bioenergetics at single-cell resolution
Bertan, F.; Wischhof, L.; Scifo, E.; Guranda, M.; Jackson, J.; Marsal-Cots, A.; Piazzesi, A.; Stork, M.; Peitz, M.; Prehn, J. H. M.; Ehninger, D.; Nicotera, P.; Bano, D.
10.1101/2020.12.07.414730 — cell biology — Posted on 2020-12-07
3174 Structural basis for piRNA-targeting
Anzelon, T. A.; Chowdhury, S.; Hughes, S. M.; Xiao, Y.; Lander, G. C.; MacRae, I. J.
10.1101/2020.12.07.413112 — molecular biology — Posted on 2020-12-07
3175 Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function
Leon, K. E.; Flynn, R. E.; Khalid, M. M.; Fontaine, K. A.; Nguyen, T.; Kumar, R.; Simoneau, C. R.; Tomar, S.; Jimenez-Morales, D.; Dunlap, M.; Kaye, J. A.; Shah, P. S.; Finkbeiner, S.; Krogan, N. J.; Bertozzi, C.; Carette, J. E.; Ott, M.
10.1101/2020.12.03.410837 — microbiology — Posted on 2020-12-07
3176 Evolutionary loss of inflammasomes in carnivores to facilitate carriage of zoonotic infections
Digby, Z.; Rooney, J.; Boyle, J. P.; Verdugo, B. B.; Pickering, R.; Webster, S. J.; Monie, T.; Hopkins, L.; Kayagaki, N.; Salvesen, G.; Warming, S.; Weinert, L.; Bryant, C. E.
10.1101/2020.12.07.398529 — immunology — Posted on 2020-12-07
3178 Inhibiting cough by silencing large pore-expressing airway sensory neurons with a charged sodium channel blocker
Tochitsky, I.; Jo, S.; Andrews, N.; Kotoda, M.; Doyle, B.; Shim, J.; Talbot, S.; Roberson, D. P.; Lee, J.; Haste, L.; Jordan, S. M.; Levy, B.; Bean, B. P.; J. Woolf, C.
10.1101/2020.12.07.414763 — neuroscience — Posted on 2020-12-07
3180 BonVision - an open-source software to create and control visual environments
Lopes, G.; Farrell, K.; Horrocks, E. A. B.; Lee, C.-Y.; Morimoto, M. M.; Muzzu, T.; Papanikolaou, A.; Rodrigues, F. R.; Wheatcroft, T.; Zucca, S.; Solomon, S. G.; Saleem, A. B.
10.1101/2020.03.09.983775 — neuroscience — Posted on 2020-12-07
3181 Ribosomes act as cryosensors in plants
Wigge, P. A.; Guillaume-Schoepfer, D.; Jaeger, K. E.; Geng, F.; Doccula, F. G.; Costa, A.; Webb, A. A.
10.1101/2020.12.07.414789 — plant biology — Posted on 2020-12-07
3185 Oxidative stress conditions result in trapping of PHF-core tau (297-391) intermediates.
Maina, M. B.; Al-Hilaly, Y.; Burra, G. B.; Rickard, J.; Harrington, C.; Wischik, C.; Serpell, L.
10.1101/2020.12.07.414532 — biochemistry — Posted on 2020-12-07
3186 Population genomics of the emerging forest pathogen Neonectria neomacrospora
Nielsen, K. N.; Gopalakrishnan, S.; Korneliussen, T. S.; Skovrind, M.; Siren, K.; Petersen, B.; Sicheritz-Ponten, T.; Thomsen, I. M.; Hansen, O. K.
10.1101/2020.12.07.407155 — genomics — Posted on 2020-12-07
3187 Identifying a GSK3-TRARG1 signaling axis reveals BCL9L as a novel regulator of GLUT4 trafficking
Duan, X.; Norris, D. M.; Humphrey, S. J.; Yang, P.; Cooke, K. C.; Bultitude, W. P.; Parker, B. L.; Conway, O. J.; Burchfield, J. G.; Krycer, J. R.; Brodsky, F. M.; James, D. E.; Fazakerley, D. J.
10.1101/2020.12.07.415257 — cell biology — Posted on 2020-12-07
3191 Rapid evolution of bacterial mutualism in the plant rhizosphere
Li, E.; de Jonge, R.; Liu, C.; Jiang, H.; Friman, V.-P.; Pieterse, C. M. J.; Bakker, P. A. H. M.; Jousset, A.
10.1101/2020.12.07.414607 — microbiology — Posted on 2020-12-07
3195 First-described recently discovered non-toxic vegetal-derived furocoumarin preclinical efficacy against SARS-CoV-2: a promising antiviral herbal drug.
Galindo-Cardiel, I. J.; Toledo Nunez, A.; Celaya Fernandez, M.; Ramirez Labrada, A.; Uranga-Murillo, I.; Arias Cabrero, M.; Pardo, J.; Panzeri, E.
10.1101/2020.12.04.410340 — pharmacology and toxicology — Posted on 2020-12-07
3196 Online biophysical predictions for SARS-CoV-2 proteins
Kagami, L.; Roca-Martinez, J.; Gavalda-Garcia, J.; Ramasamy, P.; Feenstra, K. A.; Vranken, W. F.
10.1101/2020.12.04.411744 — biophysics — Posted on 2020-12-07
3197 Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity
Giroux, N. S.; Ding, S.; McClain, M. T.; Burke, T. W.; Petzold, E. W.; Chung, H. A.; Palomino, G. R.; Wang, E.; Xi, R.; Bose, S.; Rotstein, T.; Nicholson, B. P.; Chen, T.; Henao, R.; Sempowski, G. D.; Denny, T. N.; Ko, E. R.; Ginsburg, G. S.; Kraft, B. D.; Tsalik, E. L.; Woods, C. W.; Shen, X.
10.1101/2020.12.04.412155 — genomics — Posted on 2020-12-07
3198 Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic
Lubin, J. H.; Zardecki, C.; Dolan, E. M.; Lu, C.; Shen, Z.; Dutta, S.; Westbrook, J. D.; Hudson, B. P.; Goodsell, D. S.; Williams, J. K.; Voigt, M.; Sarma, V.; Xie, L.; Venkatachalam, T.; Arnold, S.; Alfaro Alvarado, L. H.; Catalfano, K.; Khan, A.; McCarthy, E.; Staggers, S.; Tinsley, B.; Trudeau, A.; Singh, J.; Whitmore, L.; Zheng, H.; Benedek, M.; Currier, J.; Dresel, M.; Duvvuru, A.; Dyszel, B.; Fingar, E.; Hennen, E. M.; Kirsch, M.; Khan, A. A.; Labrie-Cleary, C.; Laporte, S.; Lenkeit, E.; Martin, K.; Orellana, M.; Ortiz-Alvarez de la Campa, M.; Paredes, I.; Wheeler, B.; Rupert, A.; Sam, A
10.1101/2020.12.01.406637 — molecular biology — Posted on 2020-12-07
3199 A framework for predicting potential host ranges of pathogenic viruses based on receptor ortholog analysis
Du, G.; Ding, Y.; Li, H.; Wang, X.; Wang, J.; Sun, Y.; Tao, H.; Huang, X.; Xu, K.; Hong, H.; Jiang, S.; Wang, S.; Chen, H.; Bo, X.
10.1101/2020.12.07.414292 — microbiology — Posted on 2020-12-07
3200 The new generation hDHODH inhibitor MEDS433 hinders the in vitro replication of SARS-CoV-2
Calistri, A.; Luganini, A.; Conciatori, V.; Del Vecchio, C.; Sainas, S.; Boschi, D.; Lolli, M. L.; Gribaudo, G.; Parolin, C.
10.1101/2020.12.06.412759 — microbiology — Posted on 2020-12-07
3201 Efficient inhibition of SARS-CoV-2 strains by a novel ACE2-IgG4-Fc fusion protein with a stabilized hinge region
Svilenov, H. L.; Sacherl, J.; Reiter, A.; Wolff, L.; Chen, C.-C.; Wachs, F.-P.; Pippig, S.; Wolschin, F.; Buchner, J.; Brockmeyer, C.; Protzer, U.
10.1101/2020.12.06.413443 — immunology — Posted on 2020-12-07
3202 Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease
Tomchaney, M.; Contoli, M.; Mayo, J.; Baraldo, S.; Li, S.; Cabel, C.; Bull, D.; Lick, S.; Malo, J.; Knoper, S.; Kim, S.; Tram, J.; Rojas Quintero, J.; Kraft, M.; Ledford, J.; Tesfaigzi, Y.; Martinez, F. D.; Thorne, C.; Kheradmand, F.; Campos, S. K.; Papi, A.; Polverino, F.
10.1101/2020.12.07.413252 — immunology — Posted on 2020-12-07
3203 Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice
Cao, X.; Tian, Y.; Nguyen, V.; Zhang, Y.; Gao, C.; Yin, R.; Carver, W.; Fan, D.; Albrecht, H.; Cui, T.; Tan, W.
10.1101/2020.12.07.414706 — pathology — Posted on 2020-12-07
3205 Ppard is Essential in Acceleration of Pancreatic Ductal Adenocarcinoma Development by High-Fat Diet in Mutant Kras Mice
Liu, Y.; Deguchi, Y.; Wei, D.; Moussalli, M. J.; Li, D.; Colby, J. K.; Liu, F.; Wang, H.; Valentin, L. A.; Wang, J.; Zheng, X.; Ji, B.; Yao, J. C.; Zuo, x.; Shureiqi, I.
10.1101/2020.12.04.412320 — cancer biology — Posted on 2020-12-07
3207 Genomic Evidence for the Chinese Mountain Cat as a Wildcat Conspecific (Felis silvestris bieti) and Its Introgression to Domestic Cats
Yu, H.; Xing, Y.-T.; Meng, H.; He, B.; Li, W.-J.; Qi, X.-Z.; Zhao, J.-Y.; Zhuang, Y.; Xu, X.; O'Brien, S. J.; Luo, S.-J.
10.1101/2020.12.07.414243 — evolutionary biology — Posted on 2020-12-07
3209 Single cell transcriptomics of primate sensory neurons identifies cell types associated with human chronic pain
Kupari, J.; Usoskin, D.; Lou, D.; Parisien, M.; Hu, Y.; Fatt, M.; Lonnerberg, P.; Spangberg, M.; Eriksson, B.; Barkas, N.; Kharchenko, P.; Lore, K.; Khoury, S.; Diatchenko, L.; Ernfors, P.
10.1101/2020.12.07.414193 — neuroscience — Posted on 2020-12-07
3211 Mechanistic basis for ubiquitin modulation of a protein energy landscape
Carroll, E. C.; Latorraca, N. R.; Lindner, J. M.; Maguire, B. C.; Pelton, J. G.; Marqusee, S.
10.1101/2020.12.06.414011 — biophysics — Posted on 2020-12-07
3213 Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures
Khatami, S. G.; Mubeen, S.; Bharadhwaj, V. S.; Kodamullil, A. T.; Hofmann-Apitius, M.; Domingo-Fernandez, D.
10.1101/2020.12.06.413435 — bioinformatics — Posted on 2020-12-07
3214 PANOPLY: A cloud-based platform for automated and reproducible proteogenomic data analysis
Mani, D. R.; Maynard, M.; Kothadia, R.; Krug, K.; Christianson, K. E.; Heiman, D.; Clauser, K. R.; Birger, C.; Getz, G.; Carr, S. A.
10.1101/2020.12.04.410977 — bioinformatics — Posted on 2020-12-07
3215 A massively multi-scale approach to characterising tissue architecture by synchrotron micro-CT applied to the human placenta
Tun, W. M.; Poologasundarampillai, G.; Bischof, H.; Nye, G.; King, O. N. F.; Basham, M.; Tokudome, Y.; Lewis, R. M.; Johnstone, E. D.; Brownbill, P.; Darrow, M.; Chernyavsky, I. L.
10.1101/2020.12.07.411462 — bioengineering — Posted on 2020-12-07
3218 Basal Expression of Interferon-Stimulated Genes Drives Population Differences in Monocyte Susceptibility to Influenza Infection
O'Neill, M.; Quach, H.; Pothlichet, J.; Aquino, Y.; Bisiaux, A.; Zidane, N.; Deschamps, M.; Libri, V.; Hasan, M.; Zhang, S.-Y.; Zhang, Q.; Matuozzo, D.; Cobat, A.; Abel, L.; Casanova, J.-L.; Naffakh, N.; Rotival, M.; Quintana-Murci, L.
10.1101/2020.12.07.414151 — genomics — Posted on 2020-12-07
3220 Basis for the phototaxis sign reversal in the green alga Chlamydomonas reinhardtii studied by high-speed observation
Nakajima, M.; Iizuka, K.; Ueki, N.; Isu, A.; Yoshimura, K.; Nakagaki, T.; Hisabori, T.; Sato, K.; Wakabayashi, K.-i.
10.1101/2020.12.06.414052 — cell biology — Posted on 2020-12-07
3226 Tau-mediated axonal degeneration is prevented by activation of the WldS pathway
Stubbs, K.; Sealey, M.; Moreno, M. R.; Perry, V. H.; Newman, T. A.; Mudher, A.
10.1101/2020.12.06.408583 — neuroscience — Posted on 2020-12-07
3230 rt-me-fMRI: A task and resting state dataset for real-time, multi-echo fMRI methods development and validation
Heunis, S.; Breeuwer, M.; Caballero Gaudes, C.; Hellrung, L.; Huijbers, W.; Jansen, J. F.; Lamerichs, R.; Zinger, S.; Aldenkamp, A. P.
10.1101/2020.12.07.414490 — neuroscience — Posted on 2020-12-07
3234 Grid cell firing fields in a volumetric space
Grieves, R. M.; Jedidi-Ayoub, S.; Mishchanchuk, K.; Liu, A.; Renaudineau, S.; Duvelle, E.; Jeffery, K. J.
10.1101/2020.12.06.413542 — neuroscience — Posted on 2020-12-07
3235 Development of a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment.
Balderston, N. L.; Seok, D.; Makhoul, W.; Deng, Z.-D.; Girelli, T.; Teferi, M.; Smyk, N.; Jaskir, M.; Oathes, D. J.; Sheline, Y. I.
10.1101/2020.12.06.408856 — neuroscience — Posted on 2020-12-07
3237 Association of CD44-/CD24- Breast Cancer Cells with Late Stage Tumor Recurrence
Liu, C.; Qiao, X.; Zhang, Y.; Sun, L.; Ma, Q.; Yang, J.; Ai, L.; Xue, J.; Chen, G.; Zhang, H.; Ji, C.; Gu, X.; Lei, H.; Yang, Y.
10.1101/2020.12.07.414599 — physiology — Posted on 2020-12-07
3240 Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response
He, C.; Xu, K.; Zhu, X.; Dunphy, P. S.; Gudenas, B.; Lin, W.; Twarog, N.; Hover, L. D.; Kwon, C.-H.; Kasper, L. H.; Zhang, J.; Li, X.; Dalton, J.; Jonchere, B.; Mercer, K. S.; Currier, D. G.; Caufield, W.; Wang, Y.; Broniscer, A.; Wetmore, C.; Upadhyaya, S. A.; Qaddoumi, I.; Klimo, P.; Boop, F.; Gajjar, A.; Zhang, J.; Orr, B. A.; Robinson, G. W.; Monje, M.; Freeman, B. B.; Roussel, M. F.; Northcott, P. A.; Chen, T.; Rankovic, Z.; Wu, G.; Chiang, J.; Tinkle, C. L.; Shelat, A. A.; Baker, S. J.
10.1101/2020.12.06.407973 — cancer biology — Posted on 2020-12-07
3241 Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia
Chen, C.; Yu, W.; Alikarami, F.; Qiu, Q.; Chen, C.-h.; Flournoy, J.; Gao, P.; Uzun, Y.; Fang, L.; Yu, Y.; Zhu, Q.; Wang, K.; Libbrecht, C.; Felmeister, A.; Rozich, I.; Ding, Y.-y.; Hunger, S. P.; Wu, H.; Brown, P. A.; Guest, E. M.; Barrett, D. M.; Bernt, K. M.; Tan, K.
10.1101/2020.12.06.413930 — cancer biology — Posted on 2020-12-07
3242 Using Relion software within Scipion framework
Sharov, G.; Morado, D. R.; Carroni, M.; de la Rosa-Trevin, J. M.
10.1101/2020.12.06.399808 — biophysics — Posted on 2020-12-07
3248 A Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome
Sterrett, M. C.; Enyenihi, L.; Leung, S. W.; Hess, L.; Strassler, S. E.; Farchi, D.; Lee, R. S.; Withers, E. S.; Kremsky, I.; Baker, R. E.; Basrai, M. A.; Van Hoof, A.; Fasken, M. B.; Corbett, A. H.
10.1101/2020.12.06.413658 — genetics — Posted on 2020-12-07
3249 MCOLN1 gene-replacement therapy corrects neurologic dysfunction in the mouse model of mucolipidosis IV.
DeRosa, S.; Salani, M.; Smith, S.; Sangster, M.; Miller-Browne, V.; Wassmer, S.; Xiao, R.; Vandenberghe, L.; Slaugenhaupt, S.; Misko, A.; Grishchuk, Y.
10.1101/2020.12.06.413740 — genetics — Posted on 2020-12-07
3252 Spatial organization of the transcriptome in individual neurons
Wang, G.; Ang, C.-E.; Fan, J.; Wang, A.; Moffitt, J. R.; Zhuang, X.
10.1101/2020.12.07.414060 — cell biology — Posted on 2020-12-07
3253 Starvation induces shrinkage of the bacterial cytoplasm
Shi, H.; Westfall, C. S.; Kao, J.; Odermatt, P. D.; Cesar, S.; Sievert, M.; Moore, J.; Gonzalez, C. G.; Zhang, L.; Elias, J. E.; Chang, F.; Huang, K. C.; Levin, P. A.
10.1101/2020.12.06.413849 — microbiology — Posted on 2020-12-07
3255 Post release immune responses of Tasmanian devils vaccinated with an experimental devil facial tumour disease vaccine
Pye, R.; Darby, J.; Flies, A.; Fox, S.; Carver, S.; Elmer, J.; Swift, K.; Hogg, C.; Pemberton, D.; Woods, G.; Lyons, A. B.
10.1101/2020.12.06.408963 — immunology — Posted on 2020-12-07
3256 Non-autophagy role of Atg5 and NBR1 in unconventional secretion of IL-12 prevents gut dysbiosis and inflammation
Castillo, E. F.; Merkley, S. D.; Goodfellow, S. M.; Guo, Y.; Wilton, Z. E. R.; Byrum, J. R.; Schwalm, K. C.; Dinwiddie, D. L.; Gullapalli, R. R.; Deretic, V. P.; Jimenez Hernandez, A.; Bradfute, S. B.; In, J. G.
10.1101/2020.12.07.414227 — immunology — Posted on 2020-12-07
3257 Visualizing subcellular structures in neurons with expansion microscopy
Campbell, L. A.; Pannoni, K. E.; Savory, N. A.; Lal, D.; Farris, S.
10.1101/2020.12.05.408724 — neuroscience — Posted on 2020-12-07
3258 Deciphering spatio-temporal fluorescence changes using multi-threshold event detection (MTED)
Mueller, F. E.; Cherkas, V.; Stopper, G.; Caudal, L. C.; Stopper, L.; Kirchhoff, F.; Henneberger, C.; Ponimaskin, E. G.; Zeug, A.
10.1101/2020.12.06.413492 — neuroscience — Posted on 2020-12-07
3264 A precautionary solution to estimation bias in shaping safe harvest boundaries
Goto, D.; Devine, J.; Umar, I.; Fischer, S.; De Oliveira, J.; Howell, D.; Jardim, E.; Mosqueira, I.; Ono, K.
10.1101/2020.12.05.413070 — ecology — Posted on 2020-12-07
3272 GeneTerpret: a customizable multilayer approach to genomic variant prioritization and interpretation
Manshaei, R.; DeLong, S.; Andric, V.; Joshi, E.; Okello, J. B. A.; Dhir, P.; Farncombe, K. M.; Kalbfleisch, K.; Somerville, C.; Jobling, R. K.; Scherer, S. W.; Kim, R. H.; Hosseini, M.
10.1101/2020.12.04.408336 — bioinformatics — Posted on 2020-12-07
3276 Cognitive and neural bases of collateral damage during intergroup conflict
Han, X.; Zhou, S.; Fahoum, N.; Wu, T.; Gao, T.; Shamay-Tsoory, S.; Gelfand, M. J.; Wu, X.; Han, S.
10.1101/2020.12.04.411280 — neuroscience — Posted on 2020-12-07
3277 Swallowing-related neural oscillation: An intracranial EEG study
Hashimoto, H.; Takahashi, K.; Kameda, S.; Yoshida, F.; Maezawa, H.; Oshino, S.; Tani, N.; Khoo, H. M.; Yanagisawa, T.; Yoshimine, T.; Kishima, H.; Hirata, M.
10.1101/2020.12.05.412783 — neuroscience — Posted on 2020-12-07
3279 fullsibQTL: an R package for QTL mapping in biparental populations of outcrossing species
Gazaffi, R.; Amadeu, R. R.; Mollinari, M.; Rosa, J. R. B. F.; Taniguti, C. H.; Margarido, G. R. A.; Garcia, A. A. F.
10.1101/2020.12.04.412262 — bioinformatics — Posted on 2020-12-07
3281 Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed
Taub, M. A.; Conomos, M.; Keener, R. L.; Iyer, K.; Weinstock, J.; Yanek, L.; Lane, J. D.; Miller-Fleming, T.; Brody, J.; McHugh, C. T.; Jain, D.; Gogarten, S.; Laurie, C. I.; Keramati, A.; Arvanitis, M. C.; Smith, A. E.; Heavner, B. K.; Barwick, L.; Becker, L. C.; Bis, J.; Blangero, J. A.; Bleecker, E. G.; Burchard, E. S.; Celedon, J.; Chang, Y. P.; Custer, B.; Darbar, D. W.; de las Fuentes, L.; DeMeo, D.; Freedman, B. J.; Garrett, M. A.; Gladwin, M.; Heckbert, S.; Hidalgo, B.; Irvin, M. P.; Islam, T. A.; Johnson, W.; Kaab, S.; Launer, L.; Lee, J.; Liu, S.; Moscati, A.; North, K.; Peyser, P.;
10.1101/749010 — genetics — Posted on 2020-12-07
3282 SNT: A Unifying Toolbox for Quantification of Neuronal Anatomy
Arshadi, C.; Günther, U. A.; Eddison, M.; Harrington, K. I.; Ferreira, T. A.
10.1101/2020.07.13.179325 — neuroscience — Posted on 2020-12-07
3289 Genome wide natural variation of H3K27me3 selectively marks genes predicted to be important for cell differentiation in Phaeodactylum tricornutum
Zhao, X.; Rastogi, A.; Deton Cabanillas, A. F.; Ait Mohamed, O.; Cantrel, C.; Lombard, B.; Murik, O.; Genovesio, A.; Bowler, C.; Bouyer, D.; Loew, D.; Lin, X.; Veluchamy, A.; Vieira, F. R. J.; Tirichine, L.
10.1101/2019.12.26.888800 — cell biology — Posted on 2020-12-07
3290 Abnormal AMPAR-mediated synaptic plasticity, cognitive and autistic-like behaviors in a missense Fmr1 mutant mouse model of Fragile X syndrome
Prieto, M.; Folci, A.; Poupon, G.; Schiavi, S.; Buzzelli, V.; Pronot, M.; Francois, U.; Pousinha, P.; Lattuada, N.; Abelanet, S.; Castagnola, S.; Chafai, M.; Khayachi, A.; Gwizdek, C.; Brau, F.; Deval, E.; Francolini, M.; Bardoni, B.; Humeau, Y.; Trezza, V.; Martin, S.
10.1101/2020.04.19.048819 — neuroscience — Posted on 2020-12-07
3293 Low-frequency subthalamic neural oscillations are involved in explicit and implicit facial emotional processing - a local field potential study
Dondaine, T.; Duprez, J.; Houvenaghel, J.-F.; Modolo, J.; Haegelen, C.; Robert, G.; Millet, B.; Drapier, D.; Peron, J.; Grandjean, D.; Verin, M.; Sauleau, P.
10.1101/2020.10.21.348755 — neuroscience — Posted on 2020-12-07
3296 Global elongation and high shape flexibility as an evolutionary hypothesis of accommodating mammalian brains into skulls
Weisbecker, V.; Rowe, T.; Wroe, S.; Macrini, T. E.; Garland, K. L. S.; Travouillon, K. J.; Black, K.; Archer, M.; Hand, S. J.; Berlin, J.; Beck, R. M. D.; Ladeveze, S.; Sharp, A. C.; Mardon, K.; Sherratt, E.
10.1101/2020.12.06.410928 — evolutionary biology — Posted on 2020-12-07
3297 Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19
Mirabelli, C.; Wotring, J. W.; Zhang, C. J.; McCarty, S. M.; Fursmidt, R.; Frum, T.; Kadambi, N. S.; Amin, A. T.; O'Meara, T. R.; Pretto-Kernahan, C. D.; Spence, J. R.; Huang, J.; Alysandratos, K. D.; Kotton, D. N.; Handelman, S. K.; Wobus, C. E.; Weatherwax, K. J.; Mashour, G. A.; O'Meara, M. J.; Sexton, J. Z.
10.1101/2020.05.27.117184 — cell biology — Posted on 2020-12-07
3298 Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro
Frank, B.; Conzelmann, C.; Weil, T.; Gross, R.; Jungke, P.; Eggers, M.; Mueller, J. A.; Muench, J.; Kessler, U.
10.1101/2020.10.30.360545 — microbiology — Posted on 2020-12-07
3299 Genetic variability in COVID-19-related genes in the Brazilian population
Secolin, R.; de Araujo, T. K.; Gonsales, M. C.; Rocha, C. S.; Naslavsky, M. S.; De Marco, L.; Bicalho, M.; Vazquez, V. L.; Zatz, M.; Silva, W. A.; Lopes-Cendes, I.
10.1101/2020.12.04.411736 — genetics — Posted on 2020-12-06
3300 The ascending arousal system promotes optimal performance through meso-scale network integration in a visuospatial attentional task
Wainstein, G.; Rojas-Libano, D.; Alnaes, D.; Kolskar, K. K.; Endestad, T.; Laeng, B.; Ossandon, T.; Crossley, N.; Matar, E.; Shine, J.
10.1101/2020.12.04.412551 — neuroscience — Posted on 2020-12-06
3302 Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
Guiglielmoni, N.; Houtain, A.; Derzelle, A.; van Doninck, K.; Flot, J.-F.
10.1101/2020.03.16.993428 — genomics — Posted on 2020-12-06
3304 The gut hormone Allatostatin C regulates food intake and metabolic homeostasis under nutrient stress
Kubrak, O.; Jensen, L.; Ahrentloev, N.; Koyama, T.; Malita, A.; Naseem, M. T.; Lassen, M.; Nagy, S.; Texada, M. J.; Halberg, K.; Rewitz, K.
10.1101/2020.12.05.412874 — physiology — Posted on 2020-12-06
3307 The Crown Pearl: a draft genome assembly of the European freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758)
Gomes-dos-Santos, A.; Lopes-Lima, M.; Macahdo, A. M.; Marcos Ramos, A.; Usie, A.; Bolotov, I. N.; Vikhrev, I. V.; Breton, S.; Castro, L. F. C.; da Fonseca, R. R.; Geist, J.; Osterling, M. E.; Prie, V.; Teixeira, A.; Gan, H. M.; Simakov, O.; Froufe, E.
10.1101/2020.12.06.413450 — genomics — Posted on 2020-12-06
3308 Large uncertainty in individual PRS estimation impacts PRS-based risk stratification
Ding, Y.; Hou, K.; Burch, K. S.; Lapinska, S.; Prive, F.; Vilhjalmsson, B. J.; Sankararaman, S.; Pasaniuc, B.
10.1101/2020.11.30.403188 — genomics — Posted on 2020-12-06
3312 Drawing the Borders of Olfactory Space
Mayhew, E. J.; Arayata, C. J.; Gerkin, R. C.; Lee, B. K.; Magill, J. M.; Snyder, L. L.; Little, K. A.; Yu, C. W.; Mainland, J. D.
10.1101/2020.12.04.412254 — neuroscience — Posted on 2020-12-06
3314 Bridging the gap between in silico and in vivo: modeling opioid disposition in a kidney proximal tubule microphysiological system
Imaoka, T.; Huang, W.; Shum, S.; Hailey, D. W.; Chang, S.-Y.; Chapron, A.; Yeung, C. K.; Himmelfarb, J.; Isoherranen, N.; Kelly, E. J.
10.1101/2020.12.04.412239 — pharmacology and toxicology — Posted on 2020-12-06
3321 AlphaTracker: A Multi-Animal Tracking and Behavioral Analysis Tool
Chen, Z.; Zhang, R.; Zhang, Y. E.; Fang, H.-S.; Zhou, H.; Rock, R. R.; Bal, A.; Padilla-Coreano, N.; Keyes, L.; Tye, K. M.; Lu, C.
10.1101/2020.12.04.405159 — animal behavior and cognition — Posted on 2020-12-06
3323 Genomics of altitude-associated wing shape in two tropical butterflies
Montejo-Kovacevich, G.; Salazar, P. A.; Smith, S. H.; Gavilanes, K.; Bacquet, C. N.; Chan, Y. F.; Jiggins, C. D.; Meier, J. I.; Nadeau, N. J.
10.1101/2020.12.05.412882 — evolutionary biology — Posted on 2020-12-06
3327 Unusual evolution of tree frog populations in the Chernobyl exclusion zone
Car, C.; Gilles, A.; Armant, O.; Burraco, P.; Beaugelin-Seiller, K.; Gashchak, S.; Camilleri, V.; Cavalie, I.; Laloi, P.; Adam-Guillermin, C.; Orizaola, G.; Bonzom, J.-M.
10.1101/2020.12.04.412114 — ecology — Posted on 2020-12-06
3334 Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes
Wigger, L.; Barovic, M.; Brunner, A.-D.; Marzetta, F.; Schoeniger, E.; Mehl, F.; Kipke, N.; Friedland, D.; Burdet, F.; Kessler, C.; Lesche, M.; Thorens, B.; Bonifacio, E.; Legido Quigley, C.; Delerive, P.; Dahl, A.; Simons, K.; Aust, D.; Weitz, J.; Distler, M.; Schulte, A.; Mann, M.; Ibberson, M.; Solimena, M.
10.1101/2020.12.05.412338 — bioinformatics — Posted on 2020-12-06
3335 Bottom-up fabrication of a multi-component nanopore sensor that unfolds, processes and recognizes single proteins
Zhang, S.; Huang, G.; Versloot, R.; Herwig, B. M.; Souza, P. C. T. d.; Marrink, S.-J.; Maglia, G.
10.1101/2020.12.04.411884 — bioengineering — Posted on 2020-12-06
3336 Tubular lysosomes harbor active ion gradients and poise macrophages for phagocytosis
Suresh, B.; Saminathan, A.; Chakraborty, K.; Cui, C.; Becker, L.; Krishnan, Y.
10.1101/2020.12.05.413229 — cell biology — Posted on 2020-12-06
3340 Genomic basis of drought resistance in Fagus sylvatica
Pfenninger, M.; Reuss, F.; Kiebler, A.; Schönnenbeck, P.; Caliendo, C.; Gerber, S.; Cocchiararo, B.; Reuter, S.; Blüthgen, N.; Mody, K.; Mishra, B.; Balint, M.; Thines, M.; Feldmeyer, B.
10.1101/2020.12.04.411264 — plant biology — Posted on 2020-12-06
3341 Uncovering the ideal plant ideotype for maximising seed yield in Brassica napus
Siles, L.; Hassall, K. L.; Sanchis-Gritsch, C.; Eastmond, P. J.; Kurup, S.
10.1101/2020.12.04.411371 — plant biology — Posted on 2020-12-06
3346 Harnessing Colon Chip technology to identify commensal bacteria that promote host tolerance to infection
Gazzaniga, F. S.; Camacho, D.; Wu, M.; Palazzo, M. F. D. S.; Dinis, A.; Grafton, F. N.; Cartwright, M. J.; Super, M.; Kasper, D. L.; Ingber, D. E.
10.1101/2020.12.05.412353 — bioengineering — Posted on 2020-12-06
3349 Examining the boundary sharpness coefficient as an index of cortical microstructure and its relationship to age and sex in autism spectrum disorder
Olafson, E.; Bedford, S. A.; Devenyi, G. A.; Patel, R.; Tullo, S.; Park, M. T. M.; Parent, O.; Anagnostou, E.; Baron-Cohen, S.; Bullmore, E. T.; Chura, L. R.; Craig, M. C.; Ecker, C.; Floris, D. L.; Holt, R. J.; Lenroot, R.; Lerch, J. P.; Lombardo, M. V.; Murphy, D. G. M.; Raznahan, A.; Ruigrok, A. N. V.; Spencer, M. D.; Suckling, J.; Taylor, M.; The Medical Research Council Autism Imaging Multicentre Study Consortium, ; Lai, M.-C.; Chakravarty, M. M.
10.1101/2020.07.09.196212 — neuroscience — Posted on 2020-12-06
3350 Heritable functional architecture in human visual cortex
Alvarez, I.; Finlayson, N. J.; Ei, S.; de Haas, B.; Greenwood, J. A.; Schwarzkopf, D. S.
10.1101/2020.05.04.077545 — neuroscience — Posted on 2020-12-06
3351 Temporal Analysis of T-Cell Receptor-Imposed Forces via Quantitative Single Molecule FRET Measurements
Göhring, J.; Kellner, F.; Schrangl, L.; Platzer, R.; Klotzsch, E.; Stockinger, H.; Huppa, J. B.; Schuetz, G.
10.1101/2020.04.03.024299 — biophysics — Posted on 2020-12-06
3354 Lysosomal enzyme tripeptidyl peptidase 1 plays a role in degradation of beta amyloid fibrils
Cruz, D. L.; El-Banna, M.; Majumdar, A.; Sleat, D. E.; Muldowney, M.; Lobel, P.; Maxfield, F. R.
10.1101/639682 — cell biology — Posted on 2020-12-06
3355 Highly Multiplexed Immunofluorescence of the Human Kidney using Co-Detection by Indexing (CODEX)
Neumann, E. K.; Rivera, E. S.; Patterson, N. H.; Allen, J. L.; Brewer, M.; deCaestecker, M.; Fogo, A. B.; Caprioli, R. M.; Spraggins, J. M.
10.1101/2020.12.04.412429 — cell biology — Posted on 2020-12-06
3356 A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans
Qi, W.; Gromoff, E. D. v.; Xu, F.; Zhao, Q.; Yang, W.; Pfeifer, D.; Maier, W.; Long, L.; Baumeister, R.
10.1101/2020.12.04.408260 — molecular biology — Posted on 2020-12-06
3358 Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
Guiglielmoni, N.; Houtain, A.; Derzelle, A.; van Doninck, K.; Flot, J.-F.
10.1101/2020.03.16.993428 — genomics — Posted on 2020-12-06
3359 Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures
Zafferani, M.; Haddad, C.; Luo, L.; Davila-Calderon, J.; Yuan-Chiu, L.; Shema Mugisha, C.; Monaghan, A. G.; Kennedy, A. A.; Yesselman, J. D.; Gifford, R. R.; Tai, A. W.; Kutluay, S. B.; Li, M.-L.; Brewer, G.; Tolbert, B. S.; Hargrove, A. E.
10.1101/2020.12.05.409821 — microbiology — Posted on 2020-12-06
3361 Whole Genome Sequencing for Revealing the Point Mutations of SARS-CoV-2 Genome in Bangladeshi Isolates and their Structural Effects on Viral Proteins
Hossain, M. U.; Ahammad, I.; Emon, M. T. H.; Bhattacharjee, A.; Chowdhury, Z. M.; Mosaib, M. G.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2020.12.05.413377 — bioinformatics — Posted on 2020-12-06
3363 Phytotoxic tryptoquialanines produced in vivo by Penicillium digitatum are exported in extracellular vesicles
Costa, J. H.; Bazioli, J. M.; Barbosa, L. D.; dos Santos Junior, P. L. T.; Reis, F.; Klimeck, T.; Crnkovic, C. M.; Berlinck, R. G. S.; Sussulini, A.; Rodrigues, M. L.; Fill, T. P.
10.1101/2020.12.03.411132 — microbiology — Posted on 2020-12-06
3364 Gut Microbe-Targeted Choline Trimethylamine Lyase Inhibition Improves Obesity Via Rewiring of Host Circadian Rhythms
Schugar, R. C.; Gliniak, C. M.; Helsley, R. N.; Brown, A. L.; Burrows, A.; Finney, C.; Fung, K. K.; Allen, F. M.; Ferguson, D.; Gromovsky, A. D.; Neumann, C.; McMillan, A.; Buffa, J. A.; Anderson, J. T.; Mehrabian, M.; Goudarzi, M.; Willard, B.; Mak, T. D.; Armstrong, A. R.; Swanson, G.; Keshavarzian, A.; Garcia-Garcia, J. C.; Wang, Z.; Lusis, A. J.; Hazen, S. L.; Brown, J. M.
10.1101/2020.12.04.411546 — physiology — Posted on 2020-12-06
3365 Adaptive Circuit Dynamics Across Human Cortex During Evidence Accumulation in Changing Environments
Murphy, P. R.; Wilming, N.; Hernandez-Bocanegra, D. C.; Prat Ortega, G.; Donner, T. H.
10.1101/2020.01.29.924795 — neuroscience — Posted on 2020-12-06
3369 A genetic screen identifies dreammist as a regulator of sleep
Barlow, I. L.; Mackay, E.; Wheater, E.; Goel, A.; Lim, S.; Zimmerman, S.; Woods, I.; Prober, D. A.; Rihel, J.
10.1101/2020.11.18.388736 — neuroscience — Posted on 2020-12-06
3370 Atypical DNA methylation, sRNA size distribution and female gametogenesis correlate with genome compaction in Utricularia gibba
Cerantes-Perez, S. A.; Yong-Villalobos, L.; Florez-Zapata, N. M. V.; Oropeza-Aburto, A.; Rico-Resendiz, F.; Amasende-Morales, I.; Lan, T.; Martinez, O.; Vielle-Calzada, J. P.; Albert, V. A.; Herrera-Estrella, L.
10.1101/2020.12.05.413054 — plant biology — Posted on 2020-12-06
3371 The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis
Teng, L.; Feng, Y. C.; Guo, S. T.; Wang, P. L.; Wang, S. X.; Zhang, S. N.; Qi, T. F.; La, T.; Zhang, Y. Y.; Zhao, X. H.; Zhang, D.; Wang, J. Y.; Shi, Y.; Li, J. M.; Cao, H.; Liu, T.; Thorne, R. F.; Jin, L.; Shao, F.-M.; Zhang, X. D.
10.1101/2020.12.04.412536 — cancer biology — Posted on 2020-12-06
3374 RNF8 is not required for histone-to-protamine exchange in spermiogenesis
Abe, H.; Meduri, R.; Li, Z.; Andreassen, P. R.; Li, X. Z.; Namekawa, S. H.
10.1101/2020.12.05.413005 — developmental biology — Posted on 2020-12-06
3375 NGLY1 knockdown or pharmacological inhibition induces cellular autophagy
Needs, S. H.; Bootman, M. D.; Grotzke, J.; Kramer, H. B.; Allman, S. A.
10.1101/2020.12.05.400481 — cell biology — Posted on 2020-12-06
3376 The aging whole blood transcriptome reveals a potential role of FASLG in COVID-19
Chuffa, L. G.; Souza, J. d. S.; de Mello, M. C.; Neto, M. d. O.; Carvalho, R. F.
10.1101/2020.12.04.412494 — molecular biology — Posted on 2020-12-06
3377 Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection
Haddad, N. S.; Nguyen, D. C.; Kuruvilla, M. E.; Morrison-Porter, A.; Anam, F.; Cashman, K. S.; Ramonell, R. P.; Kyu, S.; Saini, A. S.; Cabrera-Mora, M.; Derrico, A.; Alter, D.; Roback, J. D.; Horwath, M.; O'Keefe, J. B.; Wu, H. M.; Wong, A.-K. I.; Dretler, A. W.; Gripaldo, R.; Lane, A. N.; Wu, H.; Lee, S.; Hernandez, M.; Engineer, V.; Varghese, J.; Le, S.; Sanz, I.; Daiss, J. L.; Lee, F. E.-H.
10.1101/2020.12.04.410589 — immunology — Posted on 2020-12-06
3378 Inferring spikes from calcium imaging in dopamine neurons
Fleming, W.; Jewell, S.; Engelhard, B.; Witten, D.; Witten, I.
10.1101/2020.12.05.412965 — neuroscience — Posted on 2020-12-06
3379 Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-induced Weight Gain in Male Mice
Morris, E. M.; Noland, R. D.; Ponte, M. E.; Montonye, M. L.; Christianson, J. A.; Stanford, J. A.; Miles, J. M.; Hayes, M. R.; Thyfault, J. P.
10.1101/2020.12.04.412460 — physiology — Posted on 2020-12-06
3380 Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas
Bonglack, E. N.; Messinger, J. E.; Cable, J. M.; Parnell, M.; Ch'ng, J.; Christofk, H. R.; Luftig, M. A.
10.1101/2020.12.04.410563 — cancer biology — Posted on 2020-12-06
3381 Cancer-specific overmethylation of histone H3 lysines is necessary for methionine addiction and malignancy
Yamamoto, J.; Inubushi, S.; Han, Q.; Tashiro, Y.; Sun, Y.; Sugisawa, N.; Hamada, K.; Nishino, H.; Aoki, Y.; Miyake, K.; Matsuyama, R.; Bouvet, M.; Endo, I.; Hoffman, R. M.
10.1101/2020.12.04.412437 — cancer biology — Posted on 2020-12-06
3382 Deletion of PI3-Kinase Promotes Myelodysplasia Through Dysregulation of Autophagy in Hematopoietic Stem Cells
Ames, K.; Kaur, I.; Shi, Y.; Tong, M. M.; Sinclair, T.; Hemmati, S.; Glushakow-Smith, S. G.; Tein, E. E.; Gurska, L.; Dubin, R.; Shan, J.; Pradhan, K.; Verma, A.; Montagna, C.; Gritsman, K.
10.1101/2020.12.04.412593 — cancer biology — Posted on 2020-12-06
3383 Genotyping common, large structural variations in 5,202 genomes using pangenomes, the Giraffe mapper, and the vg toolkit
Siren, J.; Monlong, J.; Chang, X.; Novak, A. M.; Eizenga, J. M.; Markello, C.; Sibbesen, J. A.; Hickey, G.; Chang, P.-C.; Carroll, A.; Haussler, D.; Garrison, E.; Paten, B.
10.1101/2020.12.04.412486 — bioinformatics — Posted on 2020-12-06
3385 Structural basis of FANCD2 deubiquitination by USP1-UAF1
Rennie, M. L.; Arkinson, C.; Chaugule, V. K.; Toth, R.; Walden, H.
10.1101/2020.12.05.412924 — biochemistry — Posted on 2020-12-06
3386 Structural basis of the regulation of normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2
Sato, K.; Kumar, A.; Hamada, K.; Okada, C.; Oguni, A.; Machiyama, A.; Sakuraba, S.; Nishizawa, T.; Nureki, O.; Kono, H.; Ogata, K.; Sengoku, T.
10.1101/2020.12.05.413278 — biochemistry — Posted on 2020-12-06
3387 Chromosomal-scale De novo Genome Assemblies of Cynomolgus Macaque and Common Marmoset
Jayakumar, V.; Nishimura, O.; Kadota, M.; Hirose, N.; Sano, H.; Murakawa, Y.; Yamamoto, Y.; Nakaya, M.; Tsukiyama, T.; Seita, Y.; Nakamura, S.; Kawai, J.; Sasaki, E.; Ema, M.; Kuraku, S.; Kawaji, H.; Sakakibara, Y.
10.1101/2020.12.04.411207 — genomics — Posted on 2020-12-06
3388 Aborting meiosis overcomes hybrid sterility
Mozzachiodi, S.; Tattini, L.; Llored, A.; Irizar, A.; Skofljanc, N.; D'Angiolo, M.; De Chiara, M.; Barre, B. P.; Yue, J.-X.; Lutazi, A.; Loeillet, S.; Laureau, R.; Marsit, S.; Stenberg, S.; Albaud, B.; Persson, K.; Legras, J.-L.; Dequin, S.; Warringer, J.; Nicolas, A.; Liti, G.
10.1101/2020.12.04.411579 — genetics — Posted on 2020-12-06
3389 Significant inactivation of SARS-CoV-2 by a green tea catechin, a catechin-derivative and galloylated theaflavins in vitro
Ohgitani, E.; Shin-Ya, M.; Ichitani, M.; Kobayashi, M.; Takihara, T.; Kawamoto, M.; Kinugasa, H.; Mazda, O.
10.1101/2020.12.04.412098 — microbiology — Posted on 2020-12-06
3391 Strain specific persistence in the murine lung of Aspergillus fumigatus conidia causes an Allergic Broncho-Pulmonary Aspergillosis-like disease phenotype
Jones, J. T.; Liu, K.-W.; Wang, X.; Kowalski, C. H.; Ross, B. S.; Mills, K. A. M.; Kerkaert, J. D.; Hohl, T. M.; Lofgren, L. A.; Stajich, J. E.; Obar, J. J.; Cramer, R. A.
10.1101/2020.12.04.412726 — microbiology — Posted on 2020-12-06
3392 Molecular structure of the intact bacterial flagellar basal body
Johnson, S.; Furlong, E.; Deme, J.; Nord, A. L.; Caesar, J.; Chevance, F.; Berry, R.; Hughes, K. T.; Lea, S. M.
10.1101/2020.12.05.413195 — microbiology — Posted on 2020-12-06
3393 Redefining the role of Ca2+-permeable channels in hereditary photoreceptor degeneration using the D- and L-cis enantiomers of diltiazem
Das, S.; Popp, V.; Power, M. J.; Groeneveld, K.; Melle, C.; Rogerson, L. E.; Achury, M. N.; Schwede, F.; Strasser, T.; Euler, T.; Paquet-Durand, F.; Nache, V.
10.1101/2020.12.04.411827 — neuroscience — Posted on 2020-12-06
3394 Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy
Dorado Garcia, H.; Bei, Y.; von Stebut, J.; Ibanez, G.; Imami, K.; Gurgen, D.; Rolff, J.; Helmsauer, K.; Timme, N.; Bardinet, V.; Chamorro Gonzalez, R.; MacArthur, I. C.; Pusch, F. F.; Chen, C. Y.; Schulz, J.; Wengner, A. M.; Furth, C.; Lala, B.; Eggert, A.; Seifert, G.; Hundsoerfer, P.; Kirchner, M.; Mertins, P.; Selbach, M.; Lissat, A.; Schulte, J. H.; Haase, K.; Scheer, M.; Ortiz, M. V.; Henssen, A. G.
10.1101/2020.12.04.411413 — cancer biology — Posted on 2020-12-06
3398 Commensal Microbiota Regulates Skin Barrier Function And Repair Via Signaling Through The Aryl Hydrocarbon Receptor
Uberoi, A.; Bartow-McKenney, C.; Zheng, Q.; Campbell, A.; Knight, S. A. B.; Chan, N.; Wei, M.; Lovins, V.; Bugayev, J.; Horwinski, J.; Bradley, C.; Meyer, J.; Crumrine, D.; Sutter, C. H.; Elias, P.; Mauldin, E.; Sutter, T. R.; Grice, E. A.
10.1101/2020.12.05.413096 — microbiology — Posted on 2020-12-06
3399 Soluble FAS Ligand directs human memory B cells towards antibody-secreting cells
van Asten, S. D.; Unger, P.-P.; Marsman, C.; Bliss, S.; Jorritsma, T.; Thielens, N. M.; van Ham, S. M.; Spaapen, R. M.
10.1101/2020.12.04.411959 — immunology — Posted on 2020-12-06
3400 Granzyme B skews CD4+ T cell differentiation resulting in increased intestinal pathogenicity
Hoek, K.; Greer, M. J.; Mcclanahan, K. G.; Nazmi, A.; Piazuelo, M. B.; Wilson, K. T.; Olivares-Villagomez, D.
10.1101/2020.12.04.412056 — immunology — Posted on 2020-12-06
3403 The ascending arousal system promotes optimal performance through meso-scale network integration in a visuospatial attentional task
Wainstein, G.; Rojas-Libano, D.; Alnæs, D.; Kolskår, K. K.; Endestad, T.; Laeng, B.; Ossandón, T.; Crossley, N.; Matar, E.; Shine, J.
10.1101/2020.12.04.412551 — neuroscience — Posted on 2020-12-06
3405 Diversity of developing peripheral glia revealed by single cell RNA sequencing
Tasdemir-Yilmaz, O. E.; Druckenbrod, N. R.; Olukoya, O. O.; Yung, A. R.; Bastille, I.; Pazyra-Murphy, M. F.; Sitko, A. A.; Hale, E. B.; Vigneau, S.; Gimelbrant, A. A.; Kharchenko, P. V.; Goodrich, L. V.; Segal, R. A.
10.1101/2020.12.04.411975 — neuroscience — Posted on 2020-12-06
3406 Strawberry sweetness and consumer preference are enhanced by specific volatile compounds
Fan, Z.; Hasing, T.; Johnson, T. S.; Garner, D. M.; Barbey, C. R.; Colquhoun, T. A.; Sims, C. A.; Resende, M. F.; Whitaker, V. M.
10.1101/2020.12.04.410654 — plant biology — Posted on 2020-12-06
3407 RNA and DNA G-quadruplexes bind to human Dicer and inhibit its activity
Koralewska, N.; Szczepanska, A.; Ciechanowska, K.; Wojnicka, M.; Pokornowska, M.; Milewski, M. C.; Gudanis, D.; Baranowski, D.; Nithin, C.; Bujnicki, J. M.; Gdaniec, Z.; Figlerowicz, M.; Kurzynska-Kokorniak, A.
10.1101/2020.05.05.078592 — biochemistry — Posted on 2020-12-05
3408 Non-parallel transcriptional divergence during parallel adaptation
Fischer, E. K.; Song, Y.; Hughes, K. A.; Zhou, W.; Hoke, K. L.
10.1101/761619 — evolutionary biology — Posted on 2020-12-06
3411 Are Sources of EEG and MEG rhythmic activity the same? An analysis based on BC-VARETA
Riaz, U.; Razzaq, F. A.; Paz-Linares, D.; Areces-Gonzalez, A.; Yuan, Q.; Gonzalez-Moreira, E.; Valdes-Sosa, P. A.
10.1101/748996 — neuroscience — Posted on 2020-12-05
3413 Online biophysical predictions for SARS-CoV-2 proteins
Kagami, L.; Martinez, J. R.; Garcia, J. G.; Ramasamy, P.; Feenstra, K. A. A.; Vranken, W. F.
10.1101/2020.12.04.411744 — biophysics — Posted on 2020-12-05
3414 Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity
Giroux, N. S.; Ding, S.; McClain, M. T.; Burke, T. W.; Petzold, E. W.; Chung, H. A.; Palomino, G. R.; Wang, E.; Xi, R.; Bose, S.; Rotstein, T.; Nicholson, B. P.; Chen, T.; Henao, R.; Sempowski, G. D.; Denny, T. N.; Ko, E. R.; Ginsburg, G. S.; Kraft, B. D.; Tsalik, E. L.; Woods, C. W.; Shen, X.
10.1101/2020.12.04.412155 — genomics — Posted on 2020-12-05
3415 Sinorhizobium meliloti functions required for resistance to antimicrobial NCR peptides and bacteroid differentiation
Nicoud, Q.; Barriere, Q.; Busset, N.; Bourge, M.; Le Bars, R.; Boulogne, C.; Lecroël, M.; Jenei, S.; Kereszt, A.; Kondorosi, E.; Timtchenko, T.; Alunni, B.; Mergaert, P.
10.1101/2020.12.04.412775 — microbiology — Posted on 2020-12-05
3416 Ribavirin shows antiviral activity against SARS-CoV-2 and downregulates the activity of TMPRSS2 and the expression of ACE2 in vitro
Unal, M. A.; Bitirim, C. V.; Summak, G. Y.; Bereketoglu, S.; Cevher Zeytin, I.; Besbinar, O.; Gurcan, C.; Aydos, D.; Goksoy, E.; Kocakaya, E.; Eran, Z.; Murat, M.; Demir, N.; Somers, J.; Demir, E.; Nazir, H.; Ozkan, S. A.; Ozkul, A.; Azap, A.; Yilmazer, A.; Akcali, K. C.
10.1101/2020.12.04.410092 — pharmacology and toxicology — Posted on 2020-12-05
3417 Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
Guiglielmoni, N.; Houtain, A.; Derzelle, A.; van Doninck, K.; Flot, J.-F.
10.1101/2020.03.16.993428 — genomics — Posted on 2020-12-05
3418 Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice
Matteo, G.; Hoyeck, M. P.; Blair, H. L.; Zebarth, J.; Rick, K. R.; Williams, A.; Gagne, R.; Buick, J. K.; Yauk, C.; Bruin, J. E.
10.1101/2020.09.12.294587 — pharmacology and toxicology — Posted on 2020-12-05
3420 The Impact of Digital Histopathology Batch Effect on Deep Learning Model Accuracy and Bias
Howard, F. M.; Dolezal, J.; Kochanny, S.; Schulte, J.; Chen, H.; Heij, L.; Huo, D.; Nanda, R.; Olopade, O. I.; Kather, J.; Cipriani, N.; Grossman, R.; Pearson, A. T.
10.1101/2020.12.03.410845 — bioinformatics — Posted on 2020-12-05
3421 White matter tract-oriented deformation is dependent on real-time axonal fiber orientation
Zhou, Z.; Domel, A. G.; Li, X.; Grant, G.; Kleiven, S.; Camarillo, D.; Zeineh, M.
10.1101/2020.09.01.271502 — bioengineering — Posted on 2020-12-05
3422 Benchmarking challenging small variants with linked and long reads
Wagner, J.; Olson, N. D.; Harris, L.; Khan, Z.; Farek, J.; Mahmoud, M.; Stankovic, A.; Kovacevic, V.; Wenger, A. M.; Rowell, W. J.; Xiao, C.; Yoo, B.; Miller, N.; Rosenfeld, J. A.; Ni, B.; Zarate, S.; Kirsche, M.; Aganezov, S.; Schatz, M.; Narzisi, G.; Byrska-Bishop, M.; Clarke, W.; Evani, U. S.; Markello, C.; Shafin, K.; Zhou, X.; Sidow, A.; Bansal, V.; Ebert, P.; Marschall, T.; Lansdorp, P.; Hanlon, V.; Mattsson, C.-A.; Martinez Barrio, A.; Fiddes, I. T.; Fungtammasan, A.; Chin, C.-S.; Sedlazeck, F. J.; Carroll, A.; Salit, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2020.07.24.212712 — genomics — Posted on 2020-12-05
3423 A phospho-regulated ensemble signal motif of α-TAT1 drives dynamic microtubule acetylation
Deb Roy, A.; Gross, E.; Pillai, G.; Seetharaman, S.; Etienne-Manneville, S.; Inoue, T.
10.1101/2020.09.23.310235 — cell biology — Posted on 2020-12-05
3425 Gut microbiome couples gut and brain during calorie restriction in treating obesity
Zeng, Q.; Wang, Q.; Xiang, T.; Ou, L.; Wu, X.; Cai, K.; Geng, C.; Han, M.; Li, Z.; Li, Z.; Wang, W.; Yang, T.; Li, F.; Ma, H.; Zhao, X.; Gao, H.; Mi, N.; Zhang, C.; Tong, L.; Wang, L.; Yan, B.; Yu, Z.; Lan, C.; Wang, Z.; Wang, X.; Li, Y.; Wang, J.
10.1101/2020.12.04.406579 — microbiology — Posted on 2020-12-05
3427 Do the Moroccan SARS-Cov-2 genetic diversity hamper the use of the developed universal vaccines in Morocco?
Laamarti, M.; Essabbar, A.; Alouane, T.; Kartti, S.; Bendani, H.; Boumajdi, N.; Laamarti, R.; Allam, L.; Ouadghiri, M.; Chemao-Elfihri, M. W.; Ghrifi, F.; Smyej, I.; Rahoui, J.; Benrahma, H.; Diawara, I.; Aanniz, T.; El Hafidi, N.; El Jaoudi, R.; Nejjari, C.; Amzazi, S.; Mentag, R.; Belyamani, L.; Ibrahimi, A.
10.1101/2020.06.30.181123 — genomics — Posted on 2020-12-05
3429 Social network architecture and the tempo of cumulative cultural evolution
Cantor, M.; Chimento, M.; Smeele, S. Q.; He, P.; Papageorgiou, D.; Aplin, L. M.; Farine, D. R.
10.1101/2020.12.04.411934 — evolutionary biology — Posted on 2020-12-05
3430 Sinorhizobium meliloti functions required for resistance to antimicrobial NCR peptides and bacteroid differentiation
Nicoud, Q.; Barriere, Q.; Busset, N.; Bourge, M.; Le Bars, R.; BOULOGNE, C.; Lecroël, M.; Jenei, S.; Kereszt, A.; Kondorosi, E.; Timtchenko, T.; Alunni, B.; Mergaert, P.
10.1101/2020.12.04.412775 — microbiology — Posted on 2020-12-05
3431 3'-5' crosstalk contributes to transcriptional bursting
Cavallaro, M.; Walsh, M. D.; Jones, M.; Teahan, J.; Tiberi, S.; Finkenstadt, B.; Hebenstreit, D.
10.1101/514174 — systems biology — Posted on 2020-12-05
3433 A First-in-class, Highly Selective and Cell-active AllostericInhibitor of Protein Arginine Methyltransferase 6 (PRMT6)
Shen, Y.; Li, F.; Szewczyk, M.; Halabelian, L.; Chau, I.; Eram, M. S.; Dela Sena, C.; Park, K.-S.; Meng, F.; Chen, H.; Zeng, H.; McLeod, D.; Zepeda-Velazquez, C. A.; Campbell, R. M.; Mader, M. M.; Watson, B. M.; Schapira, M.; Arrowsmith, C. H.; Al-Awar, R.; Barsyte-Lovejoy, D.; Kaniskan, H. U.; Brown, P. J.; Vedadi, M.; Jin, J.
10.1101/2020.12.04.412569 — biochemistry — Posted on 2020-12-05
3434 Integrated transcriptional analysis of the cellular and extracellular vesicle RNA content of Candida auris in response to caspofungin
Zamith Miranda, D.; Amatuzzi, R. F.; Martins, S. T.; Vieira, A. Z.; Munhoz da Rocha, I. F.; Rodrigues, M.; Trentin, G.; Almeida, F.; Nakayasu, E. S.; Nosanchuk, J. D.; Alves, L. R.
10.1101/2020.12.04.411843 — molecular biology — Posted on 2020-12-05
3435 Remodeling of the maternal gut microbiome during pregnancy is shaped by parity
Berry, A. S. F.; Pierdon, M. K.; Misic, A. M.; Sullivan, M. C.; O'Brien, K.; Chen, Y.; Baldassano, R. N.; Parsons, T. D.; Beiting, D. P.
10.1101/2020.12.04.412205 — microbiology — Posted on 2020-12-05
3436 The innate immunity protein C1QBP functions as a negative regulator of circulative transmission of Potato leafroll virus by aphids
DeBlasio, S. L.; Wilson, J.; Tamborindeguy, C.; Johnson, R.; Pinheiro, P. V.; MacCoss, M. J.; Gray, S. M.; Heck, M.
10.1101/2020.12.04.412668 — microbiology — Posted on 2020-12-05
3437 Clinical Antibiotic Resistance Patterns Across 70 Countries
Catalan, P.; Reding, C.; Blair, J.; Gudelj, I.; Iredell, J. R.; Beardmore, R. E.
10.1101/2020.12.04.411504 — microbiology — Posted on 2020-12-05
3438 Origin and evolution of the Zinc Finger Antiviral Protein
Goncalves Carneiro, D.; Takata, M. A.; Ong, H.; Shilton, A.; Bieniasz, P. D. D.
10.1101/2020.12.04.412510 — microbiology — Posted on 2020-12-05
3440 Quantifying the interplay between rapid bacterial evolution within the mouse intestine and transmission between hosts
Vasquez, K. S.; Willis, L.; Cira, N.; Ng, K. M.; Pedro, M. F.; Aranda-Diaz, A.; Rajendram, M.; Yu, F. B.; Higginbottom, S. K.; Neff, N.; Sherlock, G.; Xavier, K. B.; Quake, S.; Sonnenburg, J.; Good, B. H.; Huang, K. C.
10.1101/2020.12.04.412072 — microbiology — Posted on 2020-12-05
3443 Effect of belt electrode-skeletal muscle electrical stimulation on immobilization-induced muscle fibrosis
Honda, Y.; Tanaka, N.; Kajiwara, Y.; Kondo, Y.; Kataoka, H.; Sakamoto, J.; Akimoto, R.; Nawata, A.; Okita, M.
10.1101/2020.12.04.411355 — pathology — Posted on 2020-12-05
3445 A comprehensive map of genetic interactions in childhood cancer reveals multiple underlying biological mechanisms
Daub, J. T.; Amini, S.; Kersjes, D. J. E.; Ma, X.; Jäger, N.; Zang, J.; Pfister, S. M.; Holstege, F. C. P.; Kemmeren, P.
10.1101/2020.11.17.385120 — cancer biology — Posted on 2020-12-05
3446 precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
Olson, N. D.; Wagner, J.; McDaniel, J.; Stephens, S. H.; Westreich, S. T.; Prasanna, A. G.; Johanson, E.; Boja, E.; Maier, E. J.; Serang, O.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Kyriakidis, K.; Malousi, A.; Shafin, K.; Pesout, T.; Jain, M.; Paten, B.; Chang, P.-C.; Kolesnikov, A.; Nattestad, M.; Baid, G.; Goel, S.; Yang, H.; Carroll, A.; Eveleigh, R.; Bourgey, M.; Bourque, G.; Li, G.; MA, C.; Tang, L.; DU, Y.; Zhang, S.; Morata, J.; Tonda, R.; Parra, G.; Trotta, J.-R.; Brueffer, C.; Demirkaya-Budak, S.; Kabakci-Zorlu, D.; Turgut, D.; Kalay
10.1101/2020.11.13.380741 — bioinformatics — Posted on 2020-12-05
3449 Chloride-dependent conformational changes in the GlyT1 glycine transporter
Zhang, Y.-W.; Uchendu, S.; Leone, V.; Bradshaw, R. T.; Sangwa, N.; Forrest, L.; Rudnick, G.
10.1101/2020.08.20.259572 — biochemistry — Posted on 2020-12-05
3450 Genome-wide association study in the pseudocereal quinoa reveals selection pattern typical for crops with a short breeding history
Patirange, D. S. R.; Rey, E.; Emrani, N.; Wellman, G.; Schmid, K.; Schmoeckel, S. M.; Tester, M.; Jung, C.
10.1101/2020.12.03.410050 — genomics — Posted on 2020-12-05
3451 Region-specific expression of young small-scale duplications in the human central nervous system
Brohard-Julien, S.; Frouin, V.; Meyer, V.; Chalabi, S.; Deleuze, J.-F.; Le Floch, E.; Battail, C.
10.1101/821256 — genomics — Posted on 2020-12-05
3452 Consequences of the divergence of Methionine AdenosylTransferase
Chouhan, B. P. S.; Gade, M. H.; Martinez, D.; Toledo-Patino, S.; Laurino, P.
10.1101/2020.08.17.254151 — evolutionary biology — Posted on 2020-12-05
3453 SOX7 deficiency causes ventricular sepal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2
Hernandez-Garcia, A.; Kim, S.; Li, Y.; Kim, B. J.; Zaveri, H. P.; Jordan, V. K.; Ljungberg, M. C.; Chen, R.; Lanz, R. B.; Scott, D. A.
10.1101/2020.12.04.412288 — developmental biology — Posted on 2020-12-05
3454 Biogenesis of RNA-containing extracellular vesicles at endoplasmic reticulum membrane contact sites
Barman, B.; Ping, J.; Krystofiak, E.; Allen, R.; Prasad, N.; Vickers, K.; Patton, J. G.; Liu, Q.; Weaver, A. M.
10.1101/2020.12.04.412379 — cell biology — Posted on 2020-12-05
3456 Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
Obr, M.; Ricana, C. L.; Nikulin, N.; Feathers, J.-P. R.; Klanschnig, M.; Thader, A.; Johnson, M. C.; Vogt, V. M.; Schur, F. K.; Dick, R. A.
10.1101/2020.12.03.410175 — molecular biology — Posted on 2020-12-05
3457 Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V.; Mishra, S.; Sharma, R.; Agarwal, J.; Ghoshal, U.; Khanna, T.; Sharma, L. K.; Verma, S. K.; Tiwari, S.; Mishra, P.
10.1101/2020.06.30.172833 — microbiology — Posted on 2020-12-05
3458 Distributed Subnetworks of Depression Defined by Direct Intracranial Neurophysiology
Scangos, K. W.; Khambhati, A. N.; Daly, P. M.; Owen, L. L. W.; Manning, J. R.; Ambrose, J. B.; Austin, E.; Krystal, A. D.; Chang, E. F.
10.1101/2020.02.14.943118 — neuroscience — Posted on 2020-12-05
3460 Crosstalk between repair pathways elicits Double-Strand Breaks in alkylated DNA: implications for the action of temozolomide
FUCHS, R. P.; Isogawa, A.; Paulo, J. A.; Onizuka, K.; Takahashi, T.; Amunugama, R.; Duxin, J. P.; Fujii, S.
10.1101/2020.11.21.391326 — biochemistry — Posted on 2020-12-05
3461 A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch
Sanchez-Buso, L.; Yeats, C. A.; Taylor, B.; Goater, R. J.; Underwood, A.; Abudahab, K.; Argimon, S.; Ma, K. C.; Mortimer, T. D.; Golparian, D.; Cole, M. J.; Grad, Y. H.; Martin, I.; Raphael, B. H.; Shafer, W. M.; Spiteri, G.; Town, K.; Wi, T.; Harris, S. R.; Unemo, M.; Aanensen, D. M.
10.1101/2020.07.03.186726 — genomics — Posted on 2020-12-04
3462 Benchmarking challenging small variants with linked and long reads
Wagner, J.; Olson, N. D.; Harris, L.; Khan, Z.; Farek, J.; Mahmoud, M.; Stankovic, A.; Kovacevic, V.; Wenger, A. M.; Rowell, W. J.; Xiao, C.; Yoo, B.; Miller, N.; Rosenfeld, J. A.; Ni, B.; Zarate, S.; Kirsche, M.; Aganezov, S.; Schatz, M.; Narzisi, G.; Byrska-Bishop, M.; Clarke, W.; Evani, U. S.; Markello, C.; Shafin, K.; Zhou, X.; Sidow, A.; Bansal, V.; Ebert, P.; Marschall, T.; Lansdorp, P.; Hanlon, V.; Mattsson, C.-A.; Martinez Barrio, A.; Fiddes, I. T.; Fungtammasan, A.; Chin, C.-S.; Sedlazeck, F. J.; Carroll, A.; Salit, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2020.07.24.212712 — genomics — Posted on 2020-12-04
3463 Evolution of genome structure in the Drosophila simulans species complex
Chakraborty, M.; Chang, C.-H.; Khost, D.; Vedanayagam, J.; Adrion, J. R.; Liao, Y.; Montooth, K. L.; Meiklejohn, C. D.; Larracuente, A. M.; Emerson, J. J.
10.1101/2020.02.27.968743 — genomics — Posted on 2020-12-05
3465 Genetic architecture of 11 abdominal organ traits derived from abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; Sorokin, E.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-12-05
3466 BUBL-1 is essential for intermediate filamentorganization and apical membrane morphology
Remmelzwaal, S.; Geisler, F.; Stucchi, R.; van der Horst, S.; Pasolli, M.; Kroll, J. R.; Jarosinska, O. D.; Akhmanova, A.; Richardson, C. A.; Altelaar, A. F. M.; Leube, R. E.; Ramalho, J. J.; Boxem, M.
10.1101/2020.12.04.411520 — developmental biology — Posted on 2020-12-04
3467 Adaptive cell invasion maintains organ homeostasis
Peloggia, J.; Münch, D.; Meneses-Giles, P.; Romero-Carvajal, A.; McClain, M.; Pan, Y. A.; Piotrowski, T.
10.1101/2020.12.01.404954 — developmental biology — Posted on 2020-12-05
3470 An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis
Del Signore, S. J.; Kelley, C. F.; Messelaar, E. M.; Lemos, T.; Marchan, M. F.; Ermanoska, B.; Mund, M.; Fai, T. G.; Kaksonen, M.; Rodal, A. A.
10.1101/2020.03.06.981076 — cell biology — Posted on 2020-12-05
3472 Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of the induction of IFN-mediated innate immune defences
Herder, V.; Dee, K.; Wojtus, J.; Goldfarb, D.; Rozario, C.; Gu, Q.; Jarrett, R.; Epifano, I.; Stevenson, A.; McFarlane, S.; Stewart, M.; Szemiel, A.; Pinto, R.; Masdefiol Garriga, A.; Graham, S.; Murcia, P.; Boutell, C.
10.1101/2020.12.04.411389 — microbiology — Posted on 2020-12-04
3473 A genome-wide CRISPR/Cas9 knock-out screen identifies the DEAD box RNA helicase DDX42 as a broad antiviral inhibitor
Bonaventure, B.; Rebendenne, A.; Garcia de Gracia, F.; Tauziet, M.; McKellar, J.; Chaves Valadao, A. L.; Courgnaud, V.; Bernard, E.; Briant, L.; Gros, N.; Djilli, W.; Arnaud-Arnould, M.; Parrinello, H.; Rialle, S.; Moncorge, O.; Goujon, C.
10.1101/2020.10.28.359356 — microbiology — Posted on 2020-12-04
3475 SARS-CoV-2 Elicits Robust Adaptive Immune Responses Regardless of Disease Severity
Nielsen, S. S. F.; Vibholm, L. K.; Monrad, I.; Olesen, R.; Frattari, G. S.; Pahus, M. H.; Hojen, J. F.; Gunst, J. D.; Erikstrup, C.; Holleufer, A.; Hartmann, R.; Ostergaard, L.; Sogaard, O. S.; Schleimann, M. H.; Tolstrup, M.
10.1101/2020.10.08.331645 — immunology — Posted on 2020-12-04
3476 Cerebellar degeneration selectively disrupts continuous mental operations
McDougle, S. D.; Tsay, J.; Pitt, B.; King, M.; Saban, W.; Taylor, J. A.; Ivry, R. B.
10.1101/2020.04.08.032409 — neuroscience — Posted on 2020-12-04
3477 Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization
Lee, B. R.; Budzillo, A.; Hadley, K.; Miller, J. A.; Jarsky, T.; Baker, K.; Hill, D.; Kim, L.; Mann, R.; Ng, L.; Oldre, A.; Rajanbabu, R.; Trinh, J.; Braun, T.; Dalley, R.; Gouwens, N. W.; Kalmbach, B. E.; Kim, T. K.; Smith, K.; Soler-Llavina, G.; Sorensen, S.; Tasic, B.; Ting, J. T.; Lein, E. S.; Zeng, H.; Murphy, G.; Berg, J.
10.1101/2020.11.04.369082 — neuroscience — Posted on 2020-12-04
3480 Leukodystrophy resembling Vanishing White Matter Disease is recapitulated by brain-specific depletion of apoptosis regulator MCL-1
Cleveland, A. H.; Romero, A.; Alfonso Azcona, L.; Herrero, M.; Moy, S.; Elroy-Stein, O.; Gama, V.; Gershon, T. R.
10.1101/2020.12.02.408138 — neuroscience — Posted on 2020-12-04
3481 Remembering immunity: Neuronal ensembles in the insular cortex encode and retrieve specific immune responses
Koren, T.; Krot, M.; Boshnak, N. T.; Amer, M.; Ben-Shaanan, T.; Azulay-Debby, H.; Hajjo, H.; Avishai, E.; Schiller, M.; Haykin, H.; Korin, B.; Farfara, D.; Hakim, F.; Rosenblum, K.; Rolls, A.
10.1101/2020.12.03.409813 — neuroscience — Posted on 2020-12-04
3483 The Amsterdam Open MRI Collection, a set ofmultimodal MRI datasets for individual differenceanalyses
Snoek, L.; van der Miesen, M.; Beemsterboer, T.; van der Leij, A.; Eigenhuis, A.; Scholte, H. S.
10.1101/2020.06.16.155317 — neuroscience — Posted on 2020-12-05
3487 Increased and ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains in hexaploid wheat in a dosage-dependent manner
Adamski, N. M.; Simmonds, J.; Brinton, J. F.; Backhaus, A. E.; Chen, Y.; Smedley, M.; Hayta, S.; Florio, T.; Crane, P.; Scott, P.; Pieri, A.; Hall, O.; Barclay, E. J.; Clayton, M.; Doonan, J. H.; Nibau, C.; Uauy, C.
10.1101/2020.11.09.375154 — plant biology — Posted on 2020-12-04
3490 N-terminal VP1 truncations favor T=1 norovirus-like particles
Pogan, R.; Weiss, V. U.; Bond, K.; Dülfer, J.; Krisp, C.; Lyktey, N.; Müller-Guhl, J.; Zoratto, S.; Allmaier, G.; Jarrold, M. F.; Munoz-Fontela, C.; Schlüter, H.; Uetrecht, C.
10.1101/2020.11.25.396499 — biophysics — Posted on 2020-12-04
3491 BitEpi: A Fast and Accurate Exhaustive Higher-Order Epistasis Search
Bayat, A.; Hosking, B.; Jain, Y.; Hosking, C.; Kodikara, M.; Reti, D.; Twine, N.; C. Bauer, D.
10.1101/858282 — bioinformatics — Posted on 2020-12-04
3494 Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies
Skottvoll, F. S.; Hansen, F.; Harrison, S.; Boger, I. C. S.; Mrsa, A.; Restan, M. S.; Stein, M.; Lundanes, E.; Pedersen-Bjergaard, S.; Aizenshtadt, A.; Krauss, S.; Sullivan, G. J.; Bogen, I. L.; Wilson, S. R.
10.1101/2020.05.15.095174 — biochemistry — Posted on 2020-12-04
3495 Ubiquitin-protein ligase Ubr5 cooperates with Hedgehog signalling to promote skeletal tissue homeostasis
Mellis, D.; Staines, K. A.; Peluso, S.; Georgiou, I.; Dora, N.; Kubiak, M.; Grillo, M.; Farquharson, C.; Kinsella, E.; Thornburn, A.; Ralston, S.; Salter, D. M.; Riobo-Del Galdo, N. A.; Hill, R. E.; Ditzel, M.
10.1101/2020.12.04.411405 — genetics — Posted on 2020-12-04
3496 Flexible multivariate linear mixed models for structured multiple traits
Kim, H.; Farage, G.; Lovell, J. T.; Mckay, J. K.; Juenger, T. E.; Sen, S.
10.1101/2020.03.27.012690 — genetics — Posted on 2020-12-04
3501 Can biomass distribution across trophic levels predict trophic cascades?
Galiana, N.; Arnoldi, J.-F.; Barbier, M.; Acloque, A.; de Manzancourt, C.; Loreau, M.
10.1101/2020.04.04.025460 — ecology — Posted on 2020-12-04
3502 Highly Multiplexed Immunofluorescence of the Human Kidney using Co-Detection by Indexing (CODEX)
Neumann, E. K.; Rivera, E. S.; Patterson, N. H.; deCaestecker, M.; Fogo, A. B.; Caprioli, R. M.; Spraggins, J. M.
10.1101/2020.12.04.412429 — cell biology — Posted on 2020-12-04
3503 The Role of Aquaporin-4 in Optic Nerve Head Astrocytes in Experimental Glaucoma
Kimball, E.; Schaub, J.; Quillen, S.; Keuthan, C.; Pease, M. E.; Korneva, A.; Quigley, H.
10.1101/2020.12.04.411322 — molecular biology — Posted on 2020-12-04
3505 Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic
Lubin, J. H.; Zardecki, C.; Dolan, E. M.; Lu, C.; Shen, Z.; Dutta, S.; Westbrook, J. D.; Hudson, B. P.; Goodsell, D. S.; Williams, J. K.; Voigt, M.; Sarma, V.; Xie, L.; Venkatachalam, T.; Arnold, S.; Alfaro Alvarado, L. H.; Catalfano, K.; Khan, A.; McCarthy, E.; Staggers, S.; Tinsley, B.; Trudeau, A.; Singh, J.; Whitmore, L.; Zheng, H.; Benedek, M.; Currier, J.; Dresel, M.; Duvvuru, A.; Dyszel, B.; Fingar, E.; Hennen, E. M.; Kirsch, M.; Khan, A. A.; Labrie-Cleary, C.; Laporte, S.; Lenkeit, E.; Martin, K.; Orellana, M.; Ortiz-Alvarez de la Campa, M.; Paredes, I.; Wheeler, B.; Rupert, A.; Sam, A
10.1101/2020.12.01.406637 — molecular biology — Posted on 2020-12-04
3506 High Real-time Reporting of Domestic and Wild Animal Diseases Following Rollout of Mobile Phone Reporting System in Kenya
Njenga, M. K.; Kemunto, N.; Kahariri, S.; Holmstrom, L.; Oyas, H.; Biggers, K.; Riddle, A.; Gachohi, J.; Muturi, M.; Mwatondo, A.; Gakuya, F.; Lekolool, I.; Sitawa, R.; Apamaku, M.; Osoro, E.; Widdowson, M.-A.; Munyua, P.
10.1101/2020.12.04.411348 — microbiology — Posted on 2020-12-04
3509 GluA4 enables associative memory formation by facilitating cerebellar expansion coding
Kita, K.; Albergaria, C.; Machado, A. S.; Carey, M. R.; Mueller, M.; Delvendahl, I.
10.1101/2020.12.04.412023 — neuroscience — Posted on 2020-12-04
3510 Functional dynamics of dopamine synthesis during monetary reward and punishment processing
Hahn, A.; Reed, M. B.; Pichler, V.; Michenthaler, P.; Rischka, L.; Godbersen, G. M.; Wadsak, W.; Hacker, M.; Lanzenberger, R.
10.1101/2019.12.23.886812 — neuroscience — Posted on 2020-12-04
3511 Spike frequency adaptation supports network computations on temporally dispersed information
Salaj, D.; Subramoney, A.; Kraisnikovic, C.; Bellec, G.; Legenstein, R.; Maass, W.
10.1101/2020.05.11.081513 — neuroscience — Posted on 2020-12-04
3514 View-channel-depth light-field microscopy: real-time volumetric reconstruction of biological dynamics by deep learning
Wang, Z.; Zhu, L.; Zhang, H.; Li, G.; Li, Y.; Yang, Y.; Ding, Y.; Gao, S.; Hsiai, T. K.; Fei, P.; Zhen, M.; Yi, C.
10.1101/432807 — biophysics — Posted on 2020-12-04
3525 Recognition of Z-RNA by ADAR1 limits interferon responses
Tang, Q.; Rigby, R. E.; Young, G. R.; Korning-Hvidt, A.; Tang, T. K.; Bridgeman, A.; Townsend, A. R.; Kassiotis, G.; Rehwinkel, J.
10.1101/2020.12.04.411793 — immunology — Posted on 2020-12-04
3526 ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.
de Reuver, R.; Dierick, E.; Wiernicki, B.; Staes, K.; Seys, L.; De Meester, E.; Muyldermans, T.; Botzki, A.; Lambrecht, B.; Van Nieuwerburgh, F.; Vandenabeele, P.; Maelfait, J.
10.1101/2020.12.04.411702 — immunology — Posted on 2020-12-04
3527 Mechanism for differential recruitment of orbitostriatal transmission during outcomes and actions in alcohol dependence
Gremel, C. M.; Renteria, R.; Cazares, C.; Baltz, E. T.; Schreiner, D. C.; Yalcinbas, E. A.; Steinkellner, T.; Hnasko, T. S.
10.1101/2020.12.04.411819 — neuroscience — Posted on 2020-12-04
3532 First-described recently discovered non-toxic vegetal-derived furocoumarin preclinical efficacy against SARS-CoV-2: a promising antiviral herbal drug.
Galindo-Cardiel, I. J.; Toledo Nunez, A.; Celaya Fernandez, M.; Ramirez Labrada, A.; Uranga-Murillo, I.; Arias Cabrero, M.; Pardo, J.; Panzeri, E.
10.1101/2020.12.04.410340 — pharmacology and toxicology — Posted on 2020-12-04
3533 Concept Recognition as a Machine Translation Problem
Boguslav, M. R.; Hailu, N. D.; Bada, M.; Baumgartner, W. A.; Hunter, L. E.
10.1101/2020.12.03.410829 — bioinformatics — Posted on 2020-12-04
3539 Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
Rusten, T. E.; Khezri, R.; Holland, P.; Schoborg, T. A.; Abramovich, I.; Takats, S.; Dillard, C.; Jain, A.; OFarrell, F.; Schultz, S.; Hagopian, W.; Quintana, E. M.; Ng, R.; Katheder, N. S.; Rahman, M. M.; Brech, A.; Jasper, H.; Rusan, N.; Jahren, A. H.; Gottlieb, E.
10.1101/2020.12.04.411561 — cell biology — Posted on 2020-12-04
3540 A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans
Qi, W.; Gromoff, E. D. v.; Xu, F.; Zhao, Q.; Yang, W.; Pfeifer, D.; Maier, W.; Long, L.; Baumeiste, R.
10.1101/2020.12.04.408260 — molecular biology — Posted on 2020-12-04
3541 New insight into bacterial iron competition: A-to-I editing in ferric enterobactin uptake
Nie, W.; Wang, S.; Xu, Q.; Wang, P.; Wu, Y.; He, R.; Yiming, A.; Liang, J.; Ahmad, I.; Fu, L.; Guo, L.; Yuan, J.; Zhu, B.; Chen, G.
10.1101/2020.12.03.409276 — microbiology — Posted on 2020-12-04
3549 The influence of body side and sex on neck muscle responses to left-frontal-oblique impacts
Mühlbeier, A.; Boström, K. J.; de Lussanet de la Sabloniere, M. H. E.; Kalthoff, W.; Kraaijenbrink, C.; Hagenfeld, L.; Natrup, J.; Castro, W. H.; Wagner, H.
10.1101/2020.12.04.406421 — physiology — Posted on 2020-12-04
3550 Unscrambling cancer genomes via integrated analysis of structural variation and copy number
Shale, C.; Baber, J.; Cameron, D.; Wong, M.; Cowley, M. J.; Papenfuss, A. T.; Cuppen, E.; Priestley, P.
10.1101/2020.12.03.410860 — cancer biology — Posted on 2020-12-04
3555 MACE2K: A Text-Mining Tool to Extract Literature-based Evidence for Variant Interpretation using Machine Learning
Gupta, S.; Rao, S.; Miglani, T.; Iyer, Y.; Lin, J.; Saiyed, A. M.; Ikwuemesi, I.; McNulty, S.; Thaxton, C.; Madhavan, S.
10.1101/2020.12.03.409094 — bioinformatics — Posted on 2020-12-04
3556 The Impact of Digital Histopathology Batch Effect on Deep Learning Model Accuracy and Bias
Howard, F. M.; Dolezal, J.; Kochanny, S.; Schulte, J.; Chen, H.; Heij, L.; Huo, D.; Nanda, R.; Olopade, O. I.; Kather, J.; Grossman, R.; Pearson, A. T.
10.1101/2020.12.03.410845 — bioinformatics — Posted on 2020-12-04
3560 De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex
Chen, K.-E.; Guo, Q.; Cui, Y.; Kendall, A. K.; Hill, T. A.; Hall, R. J.; Sacharz, J.; Norwood, S. J.; Xie, B.; Leneva, N.; Yang, Z.; Ghai, R.; Stroud, D. A.; Fairlie, D. P.; Suga, H.; Jackson, L. P.; Teasdale, R. D.; Passioura, T.; Collins, B. M.
10.1101/2020.12.03.410779 — biochemistry — Posted on 2020-12-04
3561 Redox protein Memo1 coordinates FGF23-driven signaling and small Rho-GTPases in the mouse kidney
Bartos, K.; Ramakrishnan, S. K.; Braga-Lagache, S.; Haenzi, B.; Durussel, F.; Prakash Sridharan, A.; Zhu, Y.; Sheehan, D.; Hynes, N. E.; Bonny, O.; Moor, M. B.
10.1101/2020.12.04.402511 — biochemistry — Posted on 2020-12-04
3564 Predicting lineage-specific differences in open chromatin across dozens of mammalian genomes
Kaplow, I. M.; Wirthlin, M. E.; Lawler, A. J.; Brown, A. R.; Kleyman, M.; Pfenning, A. R.
10.1101/2020.12.04.410795 — genetics — Posted on 2020-12-04
3567 SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β-cells
Bevacqua, R. J.; Lam, J. Y.; Peiris, H.; Whitener, R. L.; Kim, S.; Gu, X.; Friedlander, M. S. H.; Kim, S. K.
10.1101/2020.12.03.411033 — developmental biology — Posted on 2020-12-04
3568 Direct activation of RA signaling in cardiomyocytes protects hearts from apoptosis after myocardial infarction in mice
Da Silva, F.; Jian-Motamedi, F.; Weerasinghe Arachchige, L. C.; Tison, A.; Bradford, S. T.; Lefebvre, J.; Dolle, P.; Ghyselinck, N. B.; Wagner, K. D.; Schedl, A.
10.1101/2020.12.04.395970 — developmental biology — Posted on 2020-12-04
3570 Tissue-specific safety mechanism results in opposite protein aggregation patterns during aging
Jung, R.; Lechler, M. C.; Rödelsperger, C.; Röseler, W.; Sommer, R. J.; David, D. C.
10.1101/2020.12.04.409771 — cell biology — Posted on 2020-12-04
3571 Serine Palmitoyltransferase Controls Stemness of Intestinal Progenitors
Summers, S. A.; Chaurasia, B.; Li, Y.; Kaddai, V.; Wilkerson, J. L.; Maschek, J. A.; Cox, J.; Wei, P.; Bensard, C.; Meikle, P. J.; Clevers, H.; Shayman, J.; Hirabayashi, Y.; Holland, W. L.; Rutter, J.
10.1101/2020.12.03.409128 — cell biology — Posted on 2020-12-04
3573 Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function
Leon, K. E.; Flynn, R. E.; Khalid, M. M.; Fontaine, K. A.; Nguyen, T.; Kumar, R.; Simoneau, C. R.; Tomar, S.; Jimenez-Morales, D.; Dunlap, M.; Kaye, J. A.; Shah, P. S.; Finkbeiner, S.; Krogan, N. J.; Bertozzi, C.; Carette, J. E.; Ott, M.
10.1101/2020.12.03.410837 — microbiology — Posted on 2020-12-04
3575 Epigenetic alterations underlie airway macrophage differentiation and phenotype during lung fibrosis
McErlean, P.; Bell, C. G.; Hewitt, R. J.; Busharat, Z.; Ogger, P. P.; Ghai, P.; Albers, G.; Kingston, S.; Molyneaux, P.; Beck, S.; Lloyd, C. M.; Maher, T. M.; Byrne, A. J.
10.1101/2020.12.04.410191 — immunology — Posted on 2020-12-04
3576 Coordinate Density Analysis of neuroimaging studies
Tench, C.; Tanasescu, R.; Constantinescu, C. S.; Auer, D. P.; Cottam, W.
10.1101/2020.12.03.409953 — neuroscience — Posted on 2020-12-04
3577 Bridging neuronal correlations and dimensionality reduction
Umakantha, A.; Morina, R.; Cowley, B. R.; Snyder, A. C.; Smith, M. A.; Yu, B. M.
10.1101/2020.12.04.383604 — neuroscience — Posted on 2020-12-04
3578 Deep-Learning-Based Multivariate Pattern Analysis (dMVPA): A Tutorial and a Toolbox
Kuntzelman, K. M.; Williams, J. M.; Lim, P. C.; Samal, A.; Rao, P. K.; Johnson, M. R.
10.1101/2020.12.03.410910 — neuroscience — Posted on 2020-12-04
3579 V-NeuroStack: 3D Time Stacks for Identifying Patterns in Calcium Imaging Data
Naik, A.; Kenyon, R. V.; Taheri, A.; Berger-Wolf, T.; Ibrahim, B.; Llano, D.
10.1101/2020.12.03.410761 — neuroscience — Posted on 2020-12-04
3581 In vivo Evaluation and in silico Prediction of the Toxicity of Drepanoalpha Hard capsules
Gbolo Zoawe, B.; Ngbolua Koto-te-Nyiwa, J.-P.; Tshibangu Sha-Tshibey, D.; Memvanga Bondo, P.; Tshilanda Dinangayi, D.; Matondo, A.; Kilembe Thambwe, J.; Lebwaze Masamba, B.; Nachtergael, A.; Mpiana Tshimankinda, P.; Duez, P.
10.1101/2020.12.03.411124 — pharmacology and toxicology — Posted on 2020-12-04
3583 NOTCH-YAP1/TEAD-DNMT1 axis regulates hepatocytereprogramming into intrahepatic cholangiocarcinoma
Hu, S.; Molina, L. M.; Tao, J.; Liu, S.; Hassan, M.; Singh, S.; Poddar, M.; Bell, A.; Sia, D.; Oertel, M.; Raeman, R.; Nejak-Bowen, K.; Singhi, A.; Luo, J.; Monga, S. P.; Ko, S.
10.1101/2020.12.03.410993 — cancer biology — Posted on 2020-12-04
3584 Multi-Level Attention Graph Neural Network for Clinically Interpretable Pathway-Level Biomarkers Discovery
Xing, X.; Yang, F.; Li, H.; Jiang, B.; Zhang, J.; Zhao, Y.; Huang, J.; Meng, M. Q.- H.; Yao, J.
10.1101/2020.12.03.409755 — bioinformatics — Posted on 2020-12-04
3585 Minimal information for Chemosensitivity assays (MICHA): A next-generation pipeline to enable the FAIRification of drug screening experiments
Tanoli, Z.; Aldahdooh, J.; Alam, F.; Wang, Y.; Seemab, U.; Fratelli, M.; Pavlis, P.; Hajduch, M.; Bietrix, F.; Gribbon, P.; Zaliani, A.; Hall, M. D.; Shen, M.; Brimacombe, K.; Kulesskiy, E.; Saarela, J.; Wennerberg, K.; Vaha-Koskela, M.; Tang, J.
10.1101/2020.12.03.409409 — bioinformatics — Posted on 2020-12-04
3588 Precision methylome and in vivo methylation kinetics characterization of Klebsiella pneumoniae
Fu, J.; Zhang, J.; Yang, L.; Ding, N.; Yue, L.; Zhang, X.; Lu, D.; Jia, X.; Li, C.; Guo, C.; Yin, Z.; Jiang, X.; Zhao, Y.; Chen, F.; Zhou, D.
10.1101/2020.12.04.409839 — genomics — Posted on 2020-12-04
3592 Neuroanatomical correlates of social intelligence measured by the Guilford test
Myznikov, A.; Zheltyakova, M.; Korotkov, A.; Kireev, M.; Masharipov, R.; Jagmurov, O. D.; Habel, U.; Votinov, M.
10.1101/2020.12.03.409466 — neuroscience — Posted on 2020-12-04
3593 SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2
Lei, Y.; Zhang, J.; Schiavon, C. R.; He, M.; Chen, L.; Shen, H.; Zhang, Y.; Yin, Q.; Cho, Y.; Andrade, L.; Shadel, G. S.; Hepokoski, M.; Lei, T.; Wang, H.; Zhang, J.; Yuan, J. X.- J.; Malhotra, A.; Manor, U.; Wang, S.; Yuan, Z.-Y.; Shyy, J. Y.-J.
10.1101/2020.12.04.409144 — pathology — Posted on 2020-12-04
3595 Comparative analysis of antigen-specific anti-SARS-CoV-2 antibody isotypes in COVID-19 patients
Fujigaki, H.; Inaba, M.; Osawa, M.; Moriyama, S.; Takahashi, Y.; Suzuki, T.; Yamase, K.; Yoshida, Y.; Yagura, Y.; Oyamada, T.; Takemura, M.; Doi, Y.; Saito, K.
10.1101/2020.12.04.407510 — immunology — Posted on 2020-12-04
3596 Circulating ACE2-expressing Exosomes Block SARS-CoV-2 Virus Infection as an Innate Antiviral Mechanism
El-Shennawy, L.; Hoffmann, A. D.; Dashzeveg, N. K.; Mehl, P. J.; Yu, Z.; Tokars, V. L.; Nicolaescu, V.; Ostiguin, C.; Jia, Y.; Li, L.; Furlong, K.; Mao, C.; Wysocki, J.; Batlle, D.; Hope, T. J.; Shen, Y.; Luo, Y.; Chae, Y.; Zhang, H.; Swaminathan, S.; Randall, G. C.; Demonbreun, A. R.; Ison, M. G.; Fang, D.; Liu, H.
10.1101/2020.12.03.407031 — immunology — Posted on 2020-12-04
3599 First annotated draft genomes of non-marine ostracods (Ostracoda, Crustacea) with different reproductive modes
Tran Van, P.; Anselmetti, Y.; Bast, J.; Dumas, Z.; Galtier, N.; Jaron, K. S.; Martens, K.; Parker, D. J.; Robinson-Rechavi, M.; Schwander, T.; Simion, P.; Schön, I.
10.1101/2020.12.02.409169 — evolutionary biology — Posted on 2020-12-04
3600 Nasopharyngeal microbial communities of patients infected with SARS-COV-2 that developed COVID-19.
Ventero, M. P.; Cuadrat, R. R. C.; Vidal, I.; Andrade, B. G. N.; Molina-Pardines, C.; Haro-Moreno, J. M.; Coutinho, F. H.; Merino, E.; Regitano, L. C.; Silveira, C. B.; Afli, H.; Lopez-Perez, M.; Rodriguez, J. C.
10.1101/2020.12.01.407486 — microbiology — Posted on 2020-12-04
3605 Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer's R47H mutant does the opposite
Vilalta, A.; Zhou, Y.; Sevalle, J.; Griffin, J. K.; Sato, K.; Allendorf, D. H.; De, S.; Puigdellivol, M.; Bruzas, A.; Burguillos, M. A.; Dodd, R. B.; Chen, F.; Zhang, Y.; Flagmeier, P.; Needham, L.-M.; Enomoto, M.; Qamar, S. S.; Henderson, J.; Walter, J.; Fraser, P.; Klenerman, D.; Lee, S.; St George-Hyslop, P.; Brown, G. C.
10.1101/2020.12.03.409995 — biochemistry — Posted on 2020-12-04
3606 nAdder: A scale-space approach for the 3D analysis of neuronal traces
Phan, M.-S.; Matho, K. S.; Beaurepaire, E.; Livet, J.; Chessel, A.
10.1101/2020.06.01.127035 — neuroscience — Posted on 2020-12-04
3607 Electrical synaptic transmission requires a postsynaptic scaffolding protein
Lasseigne, A. M.; Echeverry, F. A. A.; Ijaz, S.; Michel, J. C.; Martin, E. A.; Marsh, A. J.; Trujillo, E.; Marsden, K. C.; Pereda, A. E.; Miller, A. C.
10.1101/2020.12.03.410696 — neuroscience — Posted on 2020-12-04
3610 Predictability of cortical-cortical connections in the mammalian brain
Molnar, F.; Horvat, S.; Ribeiro Gomes, A. R.; Ercsey-Ravasz, M.; Knoblauch, K.; Kennedy, H.; Toroczkai, Z.
10.1101/2020.12.03.410803 — neuroscience — Posted on 2020-12-04
3613 Chemoproteomics Maps Glycolytic Targetome in Cancer Cells
Tian, Y.; Wan, N.; Ding, M.; Shao, C.; Wang, N.; Bao, Q.; Lu, W.; Hu, H.; Sun, H.; Yang, C.; Zhou, K.; Chen, S.; Wang, G.; Ye, H.; Hao, H.
10.1101/2020.11.18.387670 — cancer biology — Posted on 2020-12-04
3615 A new fish-specific gene evolves new functions in cichlid fishes
Gu, L.; Li, C.; Mao, X.; Wei, Z.; Huang, Y.; He, X.; Zhou, W.; Li, L.; Wang, D.
10.1101/2020.11.28.391342 — evolutionary biology — Posted on 2020-12-04
3617 Deep learning enables rapid and robust analysis of fluorescence lifetime imaging in photon-starved conditions
Chen, Y.-I.; Chang, Y.-J.; Liao, S.-C.; Nguyen, T. D.; Yang, J.; Kuo, Y.-A.; Hong, S.; Liu, Y.-L.; Rylander, H. G.; Santacruz, S. R.; Yankeelov, T. E.; Yeh, H.-C.
10.1101/2020.12.02.408195 — cell biology — Posted on 2020-12-04
3621 Intrinsic dynamics enhance temporal stability of stimulus representation along rodent visual cortical hierarchies
Piasini, E.; Soltuzu, L.; Muratore, P.; Caramellino, R.; Vinken, K.; Op de Beeck, H.; Balasubramanian, V.; Zoccolan, D.
10.1101/822130 — neuroscience — Posted on 2020-12-04
3623 Neuraminidase B controls neuraminidase A-dependent mucus production and evasion
Hammond, A. J.; Binsker, U.; Aggarwal, S. D.; Ortigoza, M. B.; Loomis, C.; Weiser, J. N.
10.1101/2020.12.03.409706 — microbiology — Posted on 2020-12-03
3627 Genome-wide association of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) plasma levels in the ELSA-Brasil study
Bensenor, I.; Padilha, K.; Lima, I.; Santos, R. D.; Lambert, G.; Ramin-Mangata, S.; Bittencourt, M. S.; Goulart, A. C.; Santos, I. S.; Mill, J. G.; Krieger, J. E.; Lotufo, P. A.; Pereira, A. C.
10.1101/2020.12.03.409631 — genetics — Posted on 2020-12-03
3631 CTCF-mediated Genomic Effects of BART Region on Epstein-Barr Virus Chromatin 3D Structure in Gastric Carcinoma Cells
Kim, K.-D.; Cho, S.; Kim, T.; Huh, S.; Kim, L.; Tanizawa, H.; Shin, J.-H.; Kanda, T.; Won, K. J.; Lieberman, P. M.; Cho, H.; Kang, H.
10.1101/2020.12.03.409722 — microbiology — Posted on 2020-12-03
3632 Role of Rv3351c in trafficking Mycobacterium tuberculosis bacilli in alveolar epithelial cells and its contribution to disease
Prescott, M.; Fine-Coulson, K.; Metcalfe, M.; Gupta, T.; Dookwah, M.; Pavlicek, R.; Yahyaoui Azami, H.; Reaves, B.; Hikal, A.; Tiemeyer, M.; Karls, R.; Quinn, F.
10.1101/2020.12.03.409664 — microbiology — Posted on 2020-12-03
3633 Sources of genomic diversity in the self-fertile plant pathogen, Sclerotinia sclerotiorum, and consequences for resistance breeding
Buchwaldt, L.; Garg, H.; Puri, K. D.; Durkin, J.; Adam, J.; Harrington, M.; Liabeuf, D.; Davies, A.; Hegedus, D. D.; Sharpe, A. G.; Gali, K. K.
10.1101/2020.12.03.409698 — microbiology — Posted on 2020-12-03
3635 Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation
Peter, M.; Aschauer, D. F.; Paz Pandolfo, R.; Sinning, A.; Grössl, F.; Kargl, D.; Kraitsy, K.; Burkard, T. R.; Luhmann, H. J.; Haubensak, W.; Rumpel, S.
10.1101/2020.12.03.409623 — neuroscience — Posted on 2020-12-03
3638 31P NMR Spectroscopy Demonstrates Large Amounts of Phosphohistidine in Mammalian Cells
Makwana, M. V.; van Meurs, S.; Hounslow, A. M.; Williamson, M. P.; Jackson,, R. F. W.; Muimo, R.
10.1101/2020.12.03.409540 — biochemistry — Posted on 2020-12-03
3641 Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virus
Bouvet, M.; Voigt, S.; Tagawa, T.; Albanese, M.; Chen, Y.-F. A.; Chen, Y.; Fachko, D. N.; Pich, D.; Goebel, C.; Skalsky, R.; Hammerschmidt, W.
10.1101/2020.12.03.393306 — microbiology — Posted on 2020-12-03
3642 Competition between parallel sensorimotor learning systems
Albert, S. T.; Jang, J.; Haith, A. M.; Lerner, G.; Della-Maggiore, V.; Krakauer, J. W.; Shadmehr, R.
10.1101/2020.12.01.406777 — neuroscience — Posted on 2020-12-03
3644 Molecular characterization of projection neuron subtypes in the mouse olfactory bulb
Zeppilli, S.; Ackels, T.; Attey, R.; Klimpert, N.; Boeing, S.; Crombach, A.; Schaefer, A.; Fleischmann, A.
10.1101/2020.11.30.405571 — neuroscience — Posted on 2020-12-03
3646 Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice
Schukken, K. M.; Zhu, Y.; Bakker, P. L.; Harkema, L.; Youssef, S. A.; de Bruin, A.; Foijer, F.
10.1101/2020.12.03.404186 — cancer biology — Posted on 2020-12-03
3647 MASiVar: Multisite, Multiscanner, and Multisubject Acquisitions for Studying Variability in Diffusion Weighted Magnetic Resonance Imaging
Cai, L. Y.; Yang, Q.; Kanakaraj, P.; Nath, V.; Newton, A. T.; Edmonson, H. A.; Luci, J.; Conrad, B. N.; Price, G. R.; Hansen, C. B.; Kerley, C. I.; Ramadass, K.; Yeh, F.-C.; Kang, H.; Garyfallidis, E.; Descoteaux, M.; Rheault, F.; Schilling, K. G.; Landman, B. A.
10.1101/2020.12.03.408567 — bioengineering — Posted on 2020-12-03
3649 The cis-regulatory effects of modern human-specific variants
Weiss, C. V.; Harshman, L.; Inoue, F.; Fraser, H. B.; Petrov, D. A.; Ahituv, N.; Gokhman, D.
10.1101/2020.10.07.330761 — evolutionary biology — Posted on 2020-12-03
3650 Homogeneous selection promotes microdiversity in the glacier-fed stream microbiome
Fodelianakis, S.; Washburne, A. D.; Bourquin, M.; Pramateftaki, P.; Kohler, T. J.; Styllas, M.; Tolosano, M.; De Staercke, V.; Schön, M.; Busi, S. B.; Brandani, J.; Wilmes, P.; Peter, H.; Battin, T. J.
10.1101/2020.12.03.409391 — ecology — Posted on 2020-12-03
3651 Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system of neural tube defects
Lee, J.-H.; Shin, H.; Shaker, M. R.; Kim, H. J.; Kim, J. H.; Lee, N.; Kang, M.; Cho, S.; Kwak, T. H.; Kim, J. W.; Song, M.-R.; Kwon, S.-H.; Han, D. W.; Lee, S.; Choi, S.-Y.; Rhyu, I. J.; Kim, H.; Geum, D.; Cho, I.-J.; Sun, W.
10.1101/2020.12.02.409177 — cell biology — Posted on 2020-12-03
3652 Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
Obr, M.; Ricana, C. L.; Nikulin, N.; Feathers, J.-P. R.; Klanschnig, M.; Thader, A.; Johnson, M. C.; Vogt, V. M.; Schur, F. K.; Dick, R. A.
10.1101/2020.12.03.410175 — molecular biology — Posted on 2020-12-03
3653 The inducible lac operator-repressor system is functional in zebrafish cells
Nishizaki, S. S.; McDonald, T. L.; Farnum, G. A.; Holmes, M. J.; Drexel, M. L.; Switzenberg, J. A.; Boyle, A. P.
10.1101/2020.02.10.939223 — molecular biology — Posted on 2020-12-03
3654 Adaptation of Bacillus thuringiensis to plant colonisation affects differentiation and toxicity
Lin, Y.; Alstrup, M.; Pang, J. K. Y.; Maroti, G.; Er-Rafik, M.; Tourasse, N.; Okstad, O. A.; Kovacs, A. T.
10.1101/2020.12.03.410076 — microbiology — Posted on 2020-12-03
3656 Quantitative assessment of NCLDV-host interactions predicted by co-occurrence analyses
Meng, L.; Endo, H.; Blanc-Mathieu, R.; Chaffron, S.; Hernandez-Velazquez, R.; Kaneko, H.; Ogata, H.
10.1101/2020.10.16.342030 — microbiology — Posted on 2020-12-03
3657 An Age-Specific Atlas for Delineation of White Matter Pathways in Children Aged 6-8 Years
Spencer, A. P. C.; Byrne, H.; Lee-Kelland, R.; Jary, S.; Thoresen, M.; Cowan, F.; Chakkarapani, E.; Brooks, J. C. W.
10.1101/2020.06.21.157222 — neuroscience — Posted on 2020-12-03
3661 Doxorubicin accelerates and enhances rAAV-mediated gene expression in the cortex of mouse, cat and monkey
gong, h.; Yuan, N.; Shen, Z.; Tang, C.; Shipp, S.; Qian, L.; Lu, Y.; Andolina, I. M.; Zhang, S.; Wu, J.; Yang, H.; Wang, W.
10.1101/2020.06.08.139667 — neuroscience — Posted on 2020-12-03
3663 Synaptic dysfunction caused by truncated tau is associated with hyperpolarization-activated cyclic nucleotide-gated channelopathy
Goniotaki, D.; Tamagnini, F.; Biasetti, L.; Rumpf, S. L.; Fennell, K.; Pollack, S.; Ukwesa, S.; Sun, H.; Serpell, L.; Noble, W.; Staras, K.; Hanger, D.
10.1101/2020.11.08.369488 — neuroscience — Posted on 2020-12-03
3667 An Integrated Clinical, Omic, and Image Atlas of an Evolving Metastatic Breast Cancer
Johnson, B. E.; Creason, A. L.; Stommel, J. M.; Keck, J.; Parmar, S.; Betts, C. B.; Blucher, A.; Boniface, C.; Bucher, E.; Burlingame, E. A.; Chin, K.; Eng, J.; Feiler, H. S.; Kolodzie, A.; Kong, B.; Labrie, M.; Leyshock, P.; Mitri, S.; Patterson, J.; Riesterer, J. L.; Sivagnanam, S.; Sudar, D.; Thibault, G.; Zheng, C.; Nan, X.; Heiser, L. M.; Spellman, P. T.; Thomas, G. V.; Demir, E.; Chang, Y. H.; Coussens, L. M.; Guimaraes, A. R.; Corless, C.; Goecks, J.; Bergan, R.; Mitri, Z.; Mills, G. B.; Gray, J. W.
10.1101/2020.12.03.408500 — cancer biology — Posted on 2020-12-03
3669 Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of alpha-tubulin acetylation and inhibition of breast cancer cell migration
Nielsen, A. L.; Rajabi, N.; Kudo, N.; Larsen, K. L.; Moreno-Yruela, C.; Baek, M.; Fontenas, M.; Lucidi, A.; Madsen, A. S.; Yoshida, M.; Olsen, C. A.
10.1101/2020.03.20.000380 — biochemistry — Posted on 2020-12-03
3670 Epigenetic heterogeneity after de novo assembly of native full-length Hepatitis B Virus genomes
Goldsmith, C. D.; Cohen, D.; Dubois, A.; Martinez, M.-G.; Petitjean, K.; Corlu, A.; Hernandez-Vargas, H.; Chemin, I.
10.1101/2020.05.29.122259 — genomics — Posted on 2020-12-03
3672 Evolutionary Emergence of First Animal Organisms Triggered by Environmental Mechano-Biochemical Marine Stimulation
Nguyen, N. M.; Merle, T.; Brondon-Broders, F.; Brunet, A.-C.; Sarron, F.; Jha, A.; Genisson, J.-L.; Rottinger, E.; Emmanuel, F.
10.1101/2020.12.03.407668 — evolutionary biology — Posted on 2020-12-03
3674 The Nab2 RNA binding protein promotes sex-specific splicing of Sex lethal in Drosophila neuronal tissue
Jalloh, B.; Rounds, J. C.; Brown, B.; Kremsky, I.; Banerjee, A.; Morton, D. J.; Bienkowski, R.; Fasken, M. B.; Corbett, A. H.; Moberg, K. H.
10.1101/2020.11.13.382168 — developmental biology — Posted on 2020-12-03
3675 IgM Natural Antibodies Bind HLA-E-Leader Peptide Complexes and Modulate NK Cell Cytotoxicity
Li, D.; Brackenridge, S.; Walters, L. C.; Harlos, K.; Rozbesky, D.; Cain, D. W.; Wiehe, K.; Scearce, R. M.; Barr, M.; Mu, Z.; Parks, R.; Quastel, M.; Edwards, R. J.; Alam, S. M.; Saunders, K. O.; Borrow, P.; Jones, E. Y.; Gillespie, G. M.; McMichael, A. J.; Haynes, B. F.
10.1101/2020.12.03.403014 — immunology — Posted on 2020-12-03
3676 Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs
West, P. J.; Billingsley, P.; Pruess, T.; Rueda, C.; Saunders, G. W.; Thomson, K.; Smith, M. D.; Metcalf, C. S.; Wilcox, K. S.
10.1101/2020.12.03.410266 — neuroscience — Posted on 2020-12-03
3677 Normal aging affects unconstrained three-dimensional reaching against gravity with reduced vertical precision and increased co-contraction
Wittenberg, G. F.; Tian, J.; Kortzog, N.; Wyers, L.; Van Halewyck, F.; Boisgontier, M.; Levin, O.; Swinnen, S. P.; Jonkers, I.
10.1101/2020.12.03.410001 — neuroscience — Posted on 2020-12-03
3678 Remembering immunity: Neuronal ensembles in the insular cortex encode and retrieve specific immune responses
Koren, T.; Krot, M.; Boshnak, N. T.; Amer, M.; Ben-Shaanan, T.; Azulay-Debby, H.; Hajjo, H.; Avishai, E.; Schiller, M.; Haykin, H.; Korin, B.; Farfara, D.; Hakim, F.; Rosenblum, K.; Rolls, A.
10.1101/2020.12.03.409813 — neuroscience — Posted on 2020-12-03
3684 Unusual predominance of maintenance DNA methylation in Spirodela polyrhiza
Harkess, A. E.; Bewick, A.; Lu, Z.; Fourounjian, P.; Messing, J.; Michael, T.; Schmitz, R. J.; Meyers, B. C.
10.1101/2020.12.03.410332 — plant biology — Posted on 2020-12-03
3685 Pharmacologic IRE1/XBP1s Activation Promotes Systemic Adaptive Remodeling in Obesity
Madhavan, A.; Kok, B. P.; Grandjean, J. M.; Albert, V.; Sukiasyan, A.; Rius, B.; Powers, E.; Galmozzi, A.; Saez, E.; Wiseman, L.
10.1101/2020.12.03.408716 — physiology — Posted on 2020-12-03
3686 Fas-threshold signalling in MSCs causes tumour progression and metastasis
Mohr, A.; Zwacka, R.; Brooke, G. N.; Teif, V. B.; Clarkson, C. T.; Tianyuan, C.
10.1101/2020.12.02.406918 — cancer biology — Posted on 2020-12-03
3689 Evaluating Performance of Drug Repurposing Technologies
Schuler, J.; Falls, Z.; Mangione, W.; Hudson, M. L.; Bruggemann, L.; Samudrala, R.
10.1101/2020.12.03.410274 — bioinformatics — Posted on 2020-12-03
3690 Phylogenetic Novelty Scores: a New Approach for Weighting Genetic Sequences
De Maio, N.; Alekseyenko, A. V.; Coleman-Smith, W. J.; Pardi, F.; Suchard, M. A.; Tamuri, A. U.; Truszkowski, J. M.; Goldman, N.
10.1101/2020.12.03.410100 — bioinformatics — Posted on 2020-12-03
3691 Genome-wide association study in the pseudocereal quinoa reveals selection pattern typical for crops with a short breeding history
Patirange, D. S. R.; Rey, E.; Emrani, N.; Wellman, G.; Schmid, K.; Schmoeckel, S. M.; Tester, M.; Jung, C.
10.1101/2020.12.03.410050 — genomics — Posted on 2020-12-03
3693 TENT4A poly(A) polymerase regulates translesion DNA synthesis and is mutated in endometrial cancer
Swain, U.; Sehrawat, U.; Sarusi-Portuguez, A.; Friedlander, G.; Rotkopf, R.; Ebert, C.; Paz-Elizur, T.; Dikstein, R.; Carell, T.; Geacintov, N.; Livneh, Z.
10.1101/2020.12.03.409367 — molecular biology — Posted on 2020-12-03
3694 Using a non-destructive sugar-feeding assay for sporozoite detection and estimating the extrinsic incubation period of Plasmodium falciparum in mosquito vectors
Guissou, E.; Waite, J. L.; Jones, M.; Bell, A. S.; Suh, E.; Yameogo, K. B.; Djegbe, N.; Da, D. F.; Hien, D. F.; Yerbanga, R. S.; Ouedraogo, A. G.; Dabire, R. K.; Cohuet, A.; Thomas, M. B.; Lefevre, T.
10.1101/2020.12.03.408435 — molecular biology — Posted on 2020-12-03
3696 Augmented expansion of Treg cells from healthy and autoimmune subjects via adult progenitor cell co-culture.
Reading, J. L.; Roobrouck, V.; Hull, C.; Becker, P.; Beyens, J.; Valentin-Torres, A.; Boardman, D. A.; Nova-Lamperti, E.; Stubblefield, S.; Lombardi, G.; Deans, R.; Ting, A.; Tree, T.
10.1101/2020.12.03.410316 — immunology — Posted on 2020-12-03
3697 Potentiating CD8+ T cell antitumor activity by targeting the PCSK9/LDLR axis
Yuan, J.; Cai, T.; Zheng, X.; Ren, Y.; Qi, J.; Lin, H.; Lu, X.; Chen, Z.; Chen, H.; Liu, M.; He, S.; Feng, S.; Wu, Y.; Chen, Q.; Zhang, Z.; Ding, Y.; Yang, W.
10.1101/2020.12.03.403121 — immunology — Posted on 2020-12-03
3699 Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioural, and transcriptional study
Guma, E.; Bordignon, P.; Devenyi, G. A.; Gallino, D.; Anastassiadis, C.; Cvetkovska, V.; Barry, A. D.; Snook, E.; Germann, J.; Greenwood, C. M. T.; Misic, B.; Bagot, R. C.; Chakravarty, M. M.
10.1101/2020.12.03.406454 — neuroscience — Posted on 2020-12-03
3701 Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse
Diekman, E.; van Weeghel, M.; Suarez-Farinas, M.; Argmann, C.; Wanders, R.; Visser, G.; van der Made, I.; Creemers, E.; Houten, S.
10.1101/2020.12.03.408591 — physiology — Posted on 2020-12-03
3703 Effect of human synovial fluid from osteoarthritis patients and healthy individuals on lymphatic contractility
Michalaki, E.; Nepiyushchikh, Z. V.; Bernard, F. C.; Rudd, J. M.; Mukherjee, A.; McKinney, J. M.; Doan, T. N.; Willett, N. J.; Dixon, J. B.
10.1101/2020.12.02.408294 — bioengineering — Posted on 2020-12-03
3704 Guidelines for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples
Kubik, S.; Marques, A. C.; Xing, X.; Silvery, J.; Bertelli, C.; De Maio, F.; Pournaras, S.; Burr, T.; Duffourd, Y.; Siemens, H.; Alloui, C.; Song, L.; Wenger, Y.; Saitta, A.; Macheret, M.; Smith, E. W.; Menu, P.; Brayer, M.; Steinmetz, L. M.; Si-Mohammed, A.; Chuisseu, J.; Stevens, R.; Constantoulakis, P.; Sali, M.; Greub, G.; Tiemann, C.; Pelechano, V.; Willig, A.; Xu, Z.
10.1101/2020.12.01.405738 — genomics — Posted on 2020-12-03
3705 Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex trait variants using single nucleus ATAC-seq
Benaglio, P.; Newsome, J.; Han, J. Y.; Chiou, J.; Aylward, A.; Corban, S.; Okino, M.-L.; Kaur, J.; Gorkin, D.; Gaulton, K. J.
10.1101/2020.12.03.387894 — genomics — Posted on 2020-12-03
3708 Transcriptional response modules characterise IL-1β and IL-6 activity in COVID-19
Bell, L. C. K.; Meydan, C.; Kim, J.; Foox, J.; Butler, D.; Mason, C. E.; Shapira, S. D.; Noursadeghi, M.; Pollara, G.
10.1101/2020.07.22.202275 — immunology — Posted on 2020-12-03
3709 Functional and genomic adaptations of blood monocytes to pregravid obesity during pregnancy
Messaoudi, I.; Sureshchandra, S.; Marshall, N. E.; Mendoza, N.; Jankeel, A.; Zulu, M. Z.
10.1101/2020.12.02.409185 — immunology — Posted on 2020-12-03
3714 Ultra-high field (7T) functional magnetic resonance imaging in amyotrophic lateral sclerosis
Barry, R.; Babu, S.; Anteraper, S.; Triantafyllou, C.; Keil, B.; Rowe, O.; Rangaprakash, D.; Paganoni, S.; Lawson, R.; Dheel, C.; Cernasov, P.; Rosen, B.; Ratai, E.-M.; Atassi, N.
10.1101/2020.12.02.408278 — neuroscience — Posted on 2020-12-03
3716 A Complex Containing HNRNPA2B1 and N6-methyladenosine Modified Transcripts Mediates Actions of Toxic Tau Oligomers
Jiang, L.; Lin, W.; Zhang, C.; Verma, M.; Kwan, J.; Vliet, E. v.; Ash, P. E. A.; Cruz, A. L.; Boudeau, S.; Maziuk, B. F.; Lei, S.; Song, J.; Alvarez, V. E.; Kayed, R.; Kanaan, N.; Murray, M. E.; Crary, J. F.; Petrucelli, L.; Li, H. E.; Emili, A.; Wolozin, B.
10.1101/2020.12.03.409334 — neuroscience — Posted on 2020-12-03
3719 Microarthropod contributions to fitness variation in the common moss Ceratodon purpureus
Shortlidge, E. E.; Payton, A. C.; Carey, S. B.; McDaniel, S. F.; Rosenstiel, T. N.; Eppley, S. M.
10.1101/2020.12.02.408872 — plant biology — Posted on 2020-12-03
3720 Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study.
Millar, J.; Wildi, K.; Bartnikowski, N.; Bouquet, M.; Hyslop, K.; Passmore, M. R.; Ki, K. K.; See Hoe, L. E.; Obonyo, N. G.; Neyton, L.; Pedersen, S.; Rozencwajg, S.; Baillie, J. K.; Li Bassi, G.; Suen, J. Y.; McAuley, D. F.; Fraser, J. F.
10.1101/2020.12.02.408682 — physiology — Posted on 2020-12-03
3721 Pharmacologic inhibition of Protein Kinase C α and Protein Kinase C β halts renal function decline indirectly, by blunting hyperphagia, and directly reduces adiposity in the ZSF1 rat model of type 2 diabetes
Wang, J.; Casimiro-Garcia, A.; Johnson, B. G.; Duffen, J.; Cain, M.; Savary, L.; Wang, S.; Nambiar, P.; Lech, M.; Zhao, S.; Xi, L.; Zhan, Y.; Olson, J.; Stejskal, J. A.; Lin, H.; Zhang, B.; Martinez, R.; Masek-Hammerman, K.; Schlerman, F. J.; Dower, K.
10.1101/2020.12.02.406892 — pharmacology and toxicology — Posted on 2020-12-03
3722 Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation
Quintanal-Villalonga, A.; Taniguchi, H.; Hasan, M. A.; Meng, F.; Uddin, F.; Donoghue, M.; Won, H. H.; Chavan, S. S.; Chan, J. M.; Ciampricotti, M.; Chow, A.; Offin, M.; Chang, J. C.; Ray-Kirton, J.; Egger, J.; Bhanot, U. K.; Silber, J.; Iacobuzio-Donahue, C. A.; Roehrl, M. H.; Hollmann, T.; Yu, H. A.; Rekhtman, N.; Poirier, J. T.; Houck-Loomis, B.; Koche, R. P.; Rudin, C. M.; Sen, T.
10.1101/2020.12.02.408476 — cancer biology — Posted on 2020-12-03
3723 The local and global geometry of trabecular bone
Callens, S. J. P.; Tourolle, D. C.; Müller, R.; Zadpoor, A. A.
10.1101/2020.12.02.408377 — bioinformatics — Posted on 2020-12-03
3727 Molecular pathways to high-level azithromycin resistance in Neisseria gonorrhoeae
Laumen, J. G. E.; Basil, S. M.; Verhoeven, E.; Abdellati, S.; De Baetselier, I.; Crucitti, T.; Xavier, B. B.; Chapelle, S.; Lammens, C.; Malhotra-Kumar, S.; Kenyon, C.
10.1101/2020.12.02.409193 — microbiology — Posted on 2020-12-03
3728 The nucleotide messenger (p)ppGpp is a co-repressor of the purine synthesis transcription regulator PurR in Firmicutes
Anderson, B. W.; Schumacher, M. A.; Yang, J.; Turdiev, A.; Turdiev, H.; He, Q.; Lee, V. T.; Brennan, R. G.; Wang, J. D.
10.1101/2020.12.02.409011 — microbiology — Posted on 2020-12-03
3729 Efficacy of Biofilm Disrupters Against Candida auris and Other Candida species
Cox, C.; VAZQUEZ, J.; Wakade, S.; Bogacz, M.; Myntti, M.; Manavathu, E. K.
10.1101/2020.12.02.409250 — microbiology — Posted on 2020-12-03
3735 A hierarchy of linguistic predictions during natural language comprehension
Heilbron, M.; Armeni, K.; Schoffelen, J.-M.; Hagoort, P.; de Lange, F. P.
10.1101/2020.12.03.410399 — neuroscience — Posted on 2020-12-03
3739 Independent parental contributions initiate zygote polarization in Arabidopsis thaliana
Wang, K.; Chen, H.; Miao, Y.; Ma, Y.; Henschen, A.; Lohmann, J. U.; Laubinger, S.; Bayer, M.
10.1101/2020.12.02.407874 — plant biology — Posted on 2020-12-03
3743 Early cis-regulatory events in the formation of retinal horizontal cells
Schick, E.; Gonzalez, K. C.; Dutta, P.; Hossain, K.; Ghinia Tegla, M. G.; Emerson, M. M.
10.1101/2020.12.02.409003 — developmental biology — Posted on 2020-12-03
3745 Single Cell Sequencing Reveals Glial Specific Responses to Tissue Processing & Enzymatic Dissociation in Mice and Humans
Marsh, S. E.; Kamath, T.; Walker, A. J.; Dissing-Olesen, L.; Hammond, T. R.; Young, A. M. H.; Abdulraouf, A.; Nadaf, N.; Dufort, C.; Murphy, S.; Kozareva, V.; Vanderburg, C.; Hong, S.; Bulstrode, H.; Hutchinson, P. J.; Gaffney, D. J.; Franklin, R. J. M.; Macosko, E. Z.; Stevens, B.
10.1101/2020.12.03.408542 — neuroscience — Posted on 2020-12-03
3746 LOCAL REGULATION AND FUNCTION OF IMPORTIN-β1 DURING TRANSCRIPTION-DEPENDENT PLASTICITY
Lee, Y. J.; Navakkode, S.; Tan, C. F.; Sze, S. K.; Sreedharan, S.; Ch'ng, T. H.
10.1101/2020.12.02.409078 — neuroscience — Posted on 2020-12-03
3748 Identification of low micromolar SARS-CoV-2 Mpro inhibitors from hits identified by in silico screens
Rossetti, G. G.; Ossorio, M.; Barriot, S.; Tropia, L.; Dionellis, V. S.; Gorgulla, C.; Arthanari, H.; Mohr, P.; Gamboni, R.; Halazonetis, T. D.
10.1101/2020.12.03.409441 — biochemistry — Posted on 2020-12-03
3752 A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients by phage display is binding to the ACE2-RBD interface and is tolerant to known RBD mutations
Bertoglio, F.; Fühner, V.; Ruschig, M.; Heine, P. A.; Rand, U.; Klünemann, T.; Meier, D.; Langreder, N.; Steinke, S.; Ballmann, R.; Schneider, K.-T.; Roth, K. D. R.; Kuhn, P.; Riese, P.; Schäckermann, D.; Korn, J.; Koch, A.; Zock-Emmenthal, S.; Becker, M.; Scholz, M.; Moreira, G. M. S. G.; Wenzel, E. V.; Russo, G.; Garritsen, H. S. P.; Casu, S.; Gerstner, A.; Roth, G.; Hermann, A.; Schirrmann, T.; Dübel, S.; Frenzel, A.; Van den Heuvel, J.; Cicin-Sain, L.; Schubert, M.; Hust, M.
10.1101/2020.12.03.409318 — bioengineering — Posted on 2020-12-03
3756 A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters.
Bricker, T.; Darling, T.; Hassan, A.; Harastani, H.; Soung, A.; Jiang, X.; Dai, Y.-N.; Zhao, H.; Adams, L.; Holtzman, M.; Bailey, A.; Case, J. B.; Fremont, D.; Klein, R. S.; Diamond, M.; Boon, A.
10.1101/2020.12.02.408823 — microbiology — Posted on 2020-12-03
3760 A general approach to explore prokaryotic protein glycosylation reveals the unique surface layer modulation of an anammox bacterium.
Pabst, M.; Grouzdev, D.; Lawson, C.; Kleikamp, H. B. C.; de Ram, C.; Louwen, R.; Lin, Y.; Lucker, S.; van Loosdrecht, M.; Laureni, M.
10.1101/2020.12.03.409086 — systems biology — Posted on 2020-12-03
3761 Newfound coding potential of transcripts unveils missing members of human protein communities
Leblanc, S.; Brunet, M. A.; Jacques, J.-F.; Lekehal, A. M.; Duclos, A.; Tremblay, A.; Bruggeman-Gascon, A.; Samandi, S.; Brunelle, M.; Cohen, A. A.; Scott, M. S.; Roucou, X.
10.1101/2020.12.02.406710 — systems biology — Posted on 2020-12-03
3766 Quantifying bacterial evolution in the wild: a birthday problem for Campylobacter lineages
Calland, J. K.; Pascoe, B.; Bayliss, S. C.; Mourkas, E.; Berthenet, E.; Thorpe, H. A.; Hitchings, M. D.; Feil, E. J.; Blaser, M. J.; Falush, D.; Sheppard, S. K.
10.1101/2020.12.02.407999 — genomics — Posted on 2020-12-03
3767 Selective neuromodulation induced by alpha-based neurofeedback learning: A double-blind randomized study
Grosselin, F.; Breton, A.; Yahia-Cherif, L.; Wang, X.; Spinelli, G.; Hugueville, L.; Fossati, P.; Attal, Y.; Navarro, X.; Chavez, M.; George, N.
10.1101/2020.12.02.406173 — neuroscience — Posted on 2020-12-03
3771 Self-beneficial belief updating as a coping mechanism for stress-induced negative affect
Czekalla, N.; Baumann, J.; Stolz, D. S.; Mayer, A. V.; Voges, J. F.; Rademacher, L.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.
10.1101/2020.12.02.408096 — neuroscience — Posted on 2020-12-03
3772 Osteoprotegerin is elevated in pulmonary fibrosis and associates with IPF progression
Habibie, H.; Putri, K.; Boorsma, C. E.; Brass, D.; Heukels, P.; Wijsenbeek-Lourens, M.; Kool, M.; van der Berge, M.; Borghuis, T.; Brandsma, C. A.; Gan, T.; Olinga, P.; Timens, W.; Kahn, N.; Kreuter, M.; Burgess, J.; Melgert, B. N.
10.1101/2020.12.02.408062 — pathology — Posted on 2020-12-03
3776 A Tunable, Simplified Model for Biological Latch Mediated Spring Actuated Systems
Cook, A.; Pandhigunta, K.; Acevedo, M. A.; Walker, A.; Didcock, R. L.; Castro, J. T.; Acharya, R.; Bhamla, M. S.; Anderson, P. S. L.; Ilton, M.
10.1101/2020.12.02.408740 — biophysics — Posted on 2020-12-03
3781 Enhancement of antimicrobial diversity in situ through relaxed symbiont specificity in an insect/actinomycete partnership
Pessotti, R. d. C.; Hansen, B. L.; Reaso, J. N.; Ceja-Navarro, J. A.; El-Hifnawi, L.; Brodie, E. L.; Traxler, M. F.
10.1101/2020.12.02.394189 — microbiology — Posted on 2020-12-03
3784 Allosteric activation of T cell antigen receptor signalling by quaternary structure relaxation
Lanz, A.-L.; Masi, G.; Porciello, N.; Cohnen, A.; Cipria, D.; Prakaash, D.; Balint, S.; Raggiaschi, R.; Galgano, D.; Cole, D.; Lepore, M.; Dushek, O.; Dustin, M.; Sansom, M.; Kalli, A. C.; Acuto, O.
10.1101/2020.12.02.407882 — immunology — Posted on 2020-12-03
3785 Behavioral, Anatomical and Genetic Convergence of Affect and Cognition in Superior Frontal Cortex
Kraljevic, N.; Schaare, H. L.; Eickhoff, S. B.; Kochunov, P.; Yeo, B. T. T.; Kharabian Masouleh, S.; Valk, S. L.
10.1101/2020.12.03.401414 — neuroscience — Posted on 2020-12-03
3789 pyActigraphy: open-source python package for actigraphy data visualisation and analysis
Hammad, G.; Reyt, M.; Beliy, N.; Baillet, M.; Deantoni, M.; Lesoinne, A.; Muto, V.; Schmidt, C.
10.1101/2020.12.03.400226 — bioinformatics — Posted on 2020-12-03
3792 A Novel Role for Nucleolin in Splice Site Selection
Shefer, K.; Boulos, A.; Gotea, V.; Chaim, Y. B.; Sperling, J.; Elnitski, L.; Sperling, R.
10.1101/2020.12.02.402354 — genomics — Posted on 2020-12-03
3794 Induced Arp2/3 complex depletion increases FMNL2/3 formin expression and filopodia formation
Dimchev, V.; Lahmann, I.; Koestler, S. A.; Kage, F.; Dimchev, G.; Steffen, A.; Stradal, T. E.; Vauti, F.; Arnold, H.-H.; Rottner, K.
10.1101/2020.12.03.409573 — cell biology — Posted on 2020-12-03
3795 Hamster PIWI proteins bind to piRNAs with stage-specific size variations during oocyte maturation
Ishino, K.; Hasuwa, H.; Yoshimura, J.; Iwasaki, Y. W.; Nishihara, H.; Seki, N. M.; Hirano, T.; Tsuchiya, M.; Ishizaki, H.; Masuda, H.; Kuramoto, T.; Saito, K.; Sakakibara, Y.; Toyoda, A.; Itoh, T.; Siomi, M. C.; Morishita, S.; Siomi, H.
10.1101/2020.12.01.407411 — molecular biology — Posted on 2020-12-03
3796 Ageing disrupts reinforcement learning whilst learning to help others is preserved
Cutler, J.; Wittmann, M.; Abdurahman, A.; Hargitai, L.; Drew, D.; Husain, M.; Lockwood, P.
10.1101/2020.12.02.407718 — neuroscience — Posted on 2020-12-03
3800 Towards robust and replicable sex differences in the intrinsic brain function of autism
Floris, D. L.; Filho, J. O. A.; Lai, M.-C.; Giavasis, S.; Oldehinkel, M.; Mennes, M.; Charman, T.; Tillmann, J.; Dumas, G.; Ecker, C.; Dell'Acqua, F.; Banaschewski, T.; Moessnang, C.; Baron-Cohen, S.; Durston, S.; Loth, E.; Murphy, D. G.; Buitelaar, J. K.; Beckmann, C.; Milham, M.; Di Martino, A.
10.1101/2020.06.09.142471 — neuroscience — Posted on 2020-12-03
3801 Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
Ordonez, L. D.; Melchor, L.; Greenow, K. R.; Kendrick, H.; Tornillo, G.; Bradford, J.; Giles, P.; Smalley, M. J.
10.1101/2020.10.30.361998 — cancer biology — Posted on 2020-12-03
3802 Thinking ahead: prediction in context as a keystone of language in humans and machines
Goldstein, A.; Zada, Z.; Buchnik, E.; Schain, M.; Price, A.; Aubrey, B.; Nastase, S. A.; Feder, A.; Emanuel, D.; Cohen, A.; Jansen, A.; Gazula, H.; Choe, G.; Rao, A.; Kim, C.; Casto, C.; Lora, F.; Flinker, A.; Devore, S.; Doyle, W.; Dugan, P.; Friedman, D.; Hassidim, A.; Brenner, M.; Matias, Y.; Norman, K. A.; Devinsky, O.; Hasson, U.
10.1101/2020.12.02.403477 — neuroscience — Posted on 2020-12-03
3803 Increasing Grain Yield in Bread Wheat by Selection for High Spike Fertility Index
Pontaroli, A. C.; Alonso, M. P.; Mirabella, N. E.; Panelo, J. S.; Franco, M. F.; Vanzetti, L. S.; Lorenzo, M.
10.1101/2020.10.30.361782 — plant biology — Posted on 2020-12-03
3804 Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
Holt, J. R.; Zeng, W.-Z.; Evans, E. L.; Woo, S.-H.; Ma, S.; Abuwarda, H.; Loud, M.; Patapoutian, A.; Pathak, M. M.
10.1101/2020.10.18.344598 — biophysics — Posted on 2020-12-03
3808 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.
10.1101/2020.11.21.392803 — biochemistry — Posted on 2020-12-03
3811 VTAM: A robust pipeline for validating metabarcoding data using internal controls
Gonzalez, A.; Dubut, V.; Corse, E.; Mekdad, R.; Dechatre, T.; Meglecz, E.
10.1101/2020.11.06.371187 — ecology — Posted on 2020-12-03
3812 Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system of neural tube defects
Sun, W.; Lee, J.-H.; Shin, H.; Shaker, M. R.; Kim, H. J.; Kim, J. H.; Lee, N.; Kang, M.; Cho, S.; Kwak, T. H.; Kim, J. W.; Song, M.-R.; Kwon, S.-H.; Han, D. W.; Lee, S.; Choi, S.-Y.; Rhyu, I. J.; Kim, H.; Geum, D.; Cho, I.-J.
10.1101/2020.12.02.409177 — cell biology — Posted on 2020-12-03
3815 Spoken language comprehension activates the primary visual cortex
Seydell-Greenwald, A.; Wang, X.; Newport, E.; Bi, Y.; Striem-Amit, E.
10.1101/2020.12.02.408765 — neuroscience — Posted on 2020-12-03
3817 CONCENTRATION OF THIOUREA IS EFFECTIVE IN BREAKING THE DORMANCY OF POTATO VARIETIES.
Ranabhat, S.; Dhital, M.; Subedi, R.; Adhikari, A.; Adhikari, B.; Shrestha, S.
10.1101/2020.12.02.407916 — plant biology — Posted on 2020-12-02
3818 Prophage-dependent recombination drives genome structural variation and phenotypic heterogeneity in Escherichia coli O157:H7
Fitzgerald, S.; Lupolova, N.; Shaaban, S.; Dallman, T. J.; Greig, D.; Allison, L.; Tongue, S. C.; Evans, J.; Henry, M. K.; McNeilly, T. N.; Bono, J. L.; Gally, D. L.
10.1101/2020.12.02.407981 — microbiology — Posted on 2020-12-02
3820 Modeling Changes in Probabilistic Reinforcement Learning during Adolescence
Xia, L.; Master, S. L.; Eckstein, M. K.; Baribault, B.; Dahl, R. E.; Wilbrecht, L.; Collins, A. G. E.
10.1101/2020.12.02.407932 — neuroscience — Posted on 2020-12-02
3828 Global Genetic Cartography of Urban Metagenomes andAnti-Microbial Resistance
Danko, D. C.; Bezdan, D.; Afshinnekoo, E.; Ahsanuddin, S.; Bhattacharya, C.; Butler, D. J.; Chng, K. R.; Donnellan, D.; Hecht, J.; Jackson, K.; Kuchin, K.; Karasikov, M.; Lyons, A.; Mak, L.; Meleshko, D.; Mustafa, H.; Mutai, B.; Neches, R. Y.; Ng, A.; Nikolayeva, O.; Nikolayeva, T.; Png, E.; Ryon, K.; Sanchez, J. L.; Shaaban, H.; Sierra, M. A.; Thomas, D.; Young, B.; Alicea, J.; Bhattacharyya, M.; Blekhman, R.; Castro-Nallar, E.; Canas, A. M.; Chatziefthimiou, A. D.; Crawford, R. W.; Desnues, C.; De Filippis, F.; Dias-Neto, E.; Dybwad, M.; Elhaik, E.; Ercolini, D.; Frolova, A.; Graf, A. B.; Gr
10.1101/724526 — microbiology — Posted on 2020-12-02
3829 Genetic and Immunological Evidence for Microbial Transfer Between the International Space Station and an Astronaut
Danko, D. C.; Singh, N. K.; Butler, D. J.; Mozsary, C.; Jiang, P.; Keshavarzian, A.; Maienschein-Cline, M.; Chlipala, G.; Afshinnekoo, E.; Bezdan, D.; Garrett-Bakelman, F.; Green, S. J.; Turek, F. W.; Vitaterna, M. H.; Venkateswaran, K.; Mason, C. E.
10.1101/2020.11.10.376954 — microbiology — Posted on 2020-12-02
3832 MTX-COVAB, a human-derived antibody with potent neutralizing activity against SARS-CoV-2 infection in vitro and in a hamster model of COVID-19
Esslinger, C.; Schmitt, S.; Weber, M.; Hillenbrand, M.; Seidenberg, J.; Zingg, A.; Townsend, C.; Eicher, B.; Rutkauskaite, J.; Riese, P.; Guzman, C. A.; Fischer, K.
10.1101/2020.12.01.406934 — immunology — Posted on 2020-12-02
3834 Network variants are similar between task and rest states
Kraus, B.; Perez, D.; Ladwig, Z.; Seitzman, B. A.; Dworetsky, A.; Petersen, S.; Gratton, C.
10.1101/2020.07.30.229492 — neuroscience — Posted on 2020-12-02
3836 Survival Analysis on Rare Events Using Group-Regularized Multi-Response Cox Regression
Li, R.; Tanigawa, Y.; Justesen, J.; Taylor, J.; Hastie, T.; Tibshirani, R. J.; Rivas, M. A.
10.1101/2020.06.21.163675 — bioinformatics — Posted on 2020-12-02
3838 Binding Profile Mapping of the S100 Protein Family Using a High-throughput Local Surface Mimetic Holdup Assay
Simon, M. A.; Bartus, E.; Mag, B.; Boros, E.; Roszjar, L.; Gogl, G.; Trave, G.; Martinek, T. A.; Nyitray, L.
10.1101/2020.12.02.407676 — biochemistry — Posted on 2020-12-02
3839 THE DYNAMIC INTERPLAY BETWEEN HOMEODOMAIN TRANSCRIPTION FACTORS AND CHROMATIN ENVIRONMENT REGULATES PRONEURAL FACTOR OUTCOMES
Ang, C. E.; Olmos, V.; Zhou, B.; Lee, Q. Y.; Sinha, R.; Narayanaswamy, A.; Mall, M.; Chesnov, K.; Sudhof, T. C.; Wernig, M.
10.1101/2020.12.02.398677 — genomics — Posted on 2020-12-02
3841 Pluripotent stem cell derived models of neurological diseases reveal early transcriptional heterogeneity
Sorek, M.; Oweis, W.; Nissim-Rafinia, M.; Maman, M.; Simon, S.; Hession, C. C.; Adiconis, X.; Simmons, S. K.; Sanjana, N.; Shi, X.; Lu, C.; Pan, J. Q.; Xu, X.; Pouladi, M. L.; Ellerby, L. M.; Zhang, F.; Levin, J. Z.; Meshorer, E.
10.1101/2020.12.02.398263 — molecular biology — Posted on 2020-12-02
3843 Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival
Baker, N.; Catta-Preta, C. M. C.; Neish, R.; Sadlova, J.; Powell, B.; Alves-Ferreira, E. V. C.; Geohegan, V.; Carnielli, J. B. T.; Newling, K.; Hughes, C.; Vojtkova, B.; Anand, J.; Mihut, A.; Walrad, P.; Wilson, L. G.; Pitchford, J. W.; Volf, P.; Mottram, J. C.
10.1101/2020.09.06.279091 — microbiology — Posted on 2020-12-02
3844 Neutralizing antibodies induced by first-generation gp41-stabilized HIV-1 envelope trimers and nanoparticles
Kumar, S.; Lin, X.; Ngo, T.; Shapero, B. A.; Sou, C.; Allen, J. D.; Copps, J.; Zhang, L.; Ozorowski, G.; He, L.; Crispin, M.; Ward, A. B.; Wilson, I. A.; Zhu, J.
10.1101/2020.12.02.408328 — microbiology — Posted on 2020-12-02
3846 COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types.
Schmiedel, B. J.; Chandra, V.; Rocha, J.; Gonzalez-Colin, C.; Bhattacharyya, S.; Madrigal, A.; Ottensmeier, C. H.; Ay, F.; Vijayanand, P.
10.1101/2020.12.01.407429 — immunology — Posted on 2020-12-02
3848 Graph-theoretical Analysis of EEG Functional Connectivity during Balance Perturbation in Traumatic Brain Injury.
Shenoy Handiru, V.; Alivar, A.; Hoxha, A.; Saleh, S.; Selvan, S. E.; Yue, G. H.; Allexandre, D.
10.1101/2020.10.08.332353 — neuroscience — Posted on 2020-12-02
3852 Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms
Puhl, A. C.; Fritch, E. J.; Lane, T. R.; Tse, L. V.; Yount, B.; Sacramento, C. Q.; Tavella, T. A.; Costa, F. T. M.; Weston, S.; Logue, J.; Frieman, M.; Premkumar, L.; Pearce, K. H.; Hurst, B. L.; Andrade, C. H.; Levi, J. A.; Johnson, N. J.; Kisthardt, S. C.; Scholle, F.; Souza, T. M.; Moorman, N. J.; Baric, R. S.; Madrid, P.; Ekins, S.
10.1101/2020.12.01.407361 — pharmacology and toxicology — Posted on 2020-12-02
3854 Triggering closure of a sialic acid TRAP transporter substrate binding protein through binding of natural or artificial substrates
Peter, M. F.; Gebhardt, C.; Glaenzer, J.; Schneberger, N.; de Boer, M.; Thomas, G. H.; Cordes, T.; Hagelueken, G.
10.1101/2020.12.02.404004 — biophysics — Posted on 2020-12-02
3866 The Nab2 RNA binding protein promotes sex-specific splicing of Sex lethal in Drosophila neuronal tissue
Jalloh, B.; Rounds, J. C.; Brown, B.; Kremsky, I.; Banerjee, A.; Morton, D. J.; Bienkowski, R.; Fasken, M. B.; Corbett, A. H.; Moberg, K. H.
10.1101/2020.11.13.382168 — developmental biology — Posted on 2020-12-02
3872 Single-cell intracellular epitope and transcript detection revealing signal transduction dynamics
Rivello, F.; van Buijtenen, E.; Matula, K.; van Buggenum, J.; Vink, P.; van Eenennaam, H.; Mulder, K. W.; Huck, W. T. S.
10.1101/2020.12.02.408120 — molecular biology — Posted on 2020-12-02
3873 A promiscuous archaeal cardiolipin synthase generating a variety of cardiolipins and phospholipids
Exterkate, M.; de Kok, N. A. W.; Andringa, R. L. H.; Wolbert, N. H. J.; Minnaard, A. J.; Driessen, A. J. M.
10.1101/2020.12.02.408559 — molecular biology — Posted on 2020-12-02
3875 In vitro analysis of colistin and ciprofloxacin antagonism of Pseudomonas aeruginosa phage PEV2 infection activities
Danis-Wlodarczyk, K. M.; Cai, A.; Chen, A.; Gittrich, M.; Sullivan, M. B.; Wozniak, D. J.; Abedon, S. T.
10.1101/2020.12.02.406561 — microbiology — Posted on 2020-12-02
3876 Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis
Shkoporov, A. N.; Khokhlova, E. V.; Stephens, N.; Hueston, C.; Seymour, S.; Scholz, D.; Ross, R. P.; Hill, C.
10.1101/2020.12.02.408625 — microbiology — Posted on 2020-12-02
3877 Effective in-vitro inactivation of SARS-CoV-2 by commercially available mouthwashes
Davies, K.; Buczkowski, H.; Welch, S. R.; Green, N.; Mawer, D.; Woodford, N.; Roberts, A. D. G.; Nixon, P.; Seymour, D.; Killip, M. J.
10.1101/2020.12.02.408047 — microbiology — Posted on 2020-12-02
3878 Structure and dynamics of the ESX-5 type VII secretion system of Mycobacterium tuberculosis
Bunduc, C. M.; Fahrenkamp, D.; Wald, J.; Ummels, R.; Bitter, W.; Houben, E. N. G.; Marlovits, T. C.
10.1101/2020.12.02.408906 — microbiology — Posted on 2020-12-02
3879 Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro
Gammeltoft, K. A.; Zhou, Y.; Galli, A.; Offersgaard, A.; Pham, L. V.; Fahnoe, U.; Feng, S.; Ramirez, S.; Bukh, J.; Gottwein, J. M.
10.1101/2020.12.02.408112 — microbiology — Posted on 2020-12-02
3882 Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B are Increased in Patients with Kidney Allograft Antibody-Mediated Rejection
Clotet-Freixas, S.; Kotlyar, M.; McEvoy, C. M.; Pastrello, C.; Rodriguez-Ramirez, S.; Farkona, S.; Cardinal, H.; Dieude, M.; Hebert, M.-J.; Li, Y.; Famure, O.; Chen, P.; Kim, S. J.; Chan, E.; Jurisica, I.; John, R.; Chruscinski, A.; Konvalinka, A.
10.1101/2020.12.02.408922 — immunology — Posted on 2020-12-02
3883 CXCR6 governs the retention of tissue-resident memory T cells to promote enhanced surveillance and control of ovarian cancer
Muthuswamy, R.; McGray, A. R.; Battaglia, S.; He, W.; Miliotto, A.; Eppolito, C. A.; Litchy, B. D.; Shrikant, P.; Odunsi, K.
10.1101/2020.12.02.401729 — immunology — Posted on 2020-12-02
3884 Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues
Yang, F.; Nielsen, S. A.; Hoh, R. A.; Lee, J.-Y.; Pham, T. D.; Jackson, K. J. L.; Roskin, K. M.; Liu, Y.; Ohgami, R. S.; Osborne, E. M.; Niemann, C. U.; Parsonnet, J.; Boyd, S. D.
10.1101/2020.12.01.407015 — immunology — Posted on 2020-12-02
3887 Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
Kennedy, L. H.; Glesaaen, E. R.; Palibrk, V.; Pannone, M.; Wang, W.; Al-Jabri, A. H.; Suganthan, R.; Meyer, N.; Lin, X.; Bergersen, L. H.; Bjoras, M.; Rinholm, J. E.
10.1101/2020.12.02.408070 — neuroscience — Posted on 2020-12-02
3889 Lack of evidence of ACE2 expression and replicative infection by SARS-CoV-2 in human endothelial cells
McCracken, I.; Saginc, G.; He, L.; Huseynov, A.; Daniels, A.; Fletcher, S.; Peghaire, C.; Kalna, V.; Mae, M. A.; Muhl, L.; Craig, N. M.; Griffiths, S. J.; Haas, J. G.; Burkard, C. T.; Lendahl, U.; Birdsey, G. M.; Betsholtz, C.; Noseda, M.; Baker, A.; Randi, A. M.
10.1101/2020.12.02.391664 — pathology — Posted on 2020-12-02
3891 Fast estimation of genetic correlation for Biobank-scale data
Wu, Y.; Burch, K. S.; Ganna, A.; Pajukanta, P.; Pasaniuc, B.; Sankararaman, S.
10.1101/525055 — bioinformatics — Posted on 2020-12-02
3892 Quantifying the effect of experimental perturbations at single-cell resolution
Burkhardt, D. B.; Stanley, J. S.; Tong, A.; Perdigoto, A. L.; Gigante, S. A.; Herold, K. C.; Wolf, G.; Giraldez, A. J.; van Dijk, D.; Krishnaswamy, S.
10.1101/532846 — bioinformatics — Posted on 2020-12-02
3893 Novel Mutations in NSP1 and PLPro of SARS-CoV-2 NIB-1 Genome Mount for Effective Therapeutics
Hossain, M. U.; Bhattacharjee, A.; Hossain Emon, M. T.; Chowdhury, Z. M.; Mosaib, M. G.; Moniruzzaman, M.; Rahman, M. H.; Islam, M. N.; Ahmed, I.; Amin, M. R.; Rashed, A.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2020.12.02.408229 — bioinformatics — Posted on 2020-12-02
3896 Species-resolved sequencing of low-biomass microbiomes by 2bRAD-M
Sun, Z.; Huang, S.; Zhu, P.; Tzehau, L.; Zhao, H.; Lv, J.; Zhang, R.; Zhou, L.; Niu, Q.; Wang, X.; Zhang, M.; Jing, G.; Bao, Z.; Liu, J.; Wang, S.; Xu, J.
10.1101/2020.12.01.405647 — microbiology — Posted on 2020-12-02
3898 Competition between parallel sensorimotor learning systems
Albert, S. T.; Jang, J.; Haith, A. M.; Lerner, G.; Della-Maggiore, V.; Krakauer, J. W.; Shadmehr, R.
10.1101/2020.12.01.406777 — neuroscience — Posted on 2020-12-02
3899 Digging roots is easier with AI
Han, E.; Smith, A. G.; Kemper, R.; White, R.; Kirkegaard, J.; Thorup-Kristensen, K.; Athmann, M.
10.1101/2020.12.01.397034 — plant biology — Posted on 2020-12-02
3900 PhenoBR: a model to phenotype body condition dynamics in meat sheep
Mace, T.; Gonzalez-Garcia, E.; Köver, G.; Hazard, D.; Taghipoor, M.
10.1101/2020.12.01.407098 — physiology — Posted on 2020-12-02
3902 Development of an Antiseizure Drug Screening Platform for Dravet Syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program
Pernici, C. D.; Mensah, J. A.; Dahle, E. J.; Johnson, K. J.; Handy, L. J.; Buxton, L. L.; Smith, M. D.; West, P. J.; Metcalf, C. S.; Wilcox, K. S.
10.1101/2020.12.01.406470 — pharmacology and toxicology — Posted on 2020-12-02
3903 Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia
Garnar-Wortzel, L.; Bishop, T. R.; Kitamura, S.; Milosevich, N.; Asiaban, J. N.; Zhang, X.; Zheng, Q.; Chen, E.; Ramos, A. R.; Ackerman, C. J.; Hampton, E. N.; Chatterjee, A. K.; Young, T. S.; Hull, M. V.; Sharpless, K. B.; Cravatt, B. F.; Wolan, D. W.; Erb, M. A.
10.1101/2020.12.01.406694 — cancer biology — Posted on 2020-12-02
3906 DNA methylation proxies for 16 plasma proteins predict the incidence of 7 leading causes of morbidity
Gadd, D. A.; Hillary, R. F.; McCartney, D. L.; Stevenson, A. J.; Nangle, C.; Campbell, A. J.; Flaig, R.; Harris, S. E.; Walker, R. M.; Shi, L.; Tucker-Drob, E. M.; McRae, A. F.; Deary, I. J.; Porteous, D. J.; Hayward, C.; Visscher, P. M.; Cox, S. R.; Evans, K. L.; McIntosh, A. M.; Marioni, R. E.
10.1101/2020.12.01.404681 — genomics — Posted on 2020-12-02
3907 Imputed Gene Expression Risk Scores: A Functionally Informed Component of Polygenic Risk
Pain, O.; Glanville, K. P.; Hagenaars, S. P.; Selzam, S.; Fürtjes, A.; Coleman, J. R.; Rimfeld, K.; Breen, G.; Folkersen, L.; Lewis, C.
10.1101/2020.12.01.369462 — genomics — Posted on 2020-12-02
3908 Postnatal persistence of sex-dependent renal developmentally programmed structural and molecular changes in nonhuman primates
Bishop, A. C.; Spradling-Reeves, K. D.; Shade, R.; Lange, K. J.; Birnbaum, S.; Favela, K.; Dick, E. J.; Nijland, M. J.; Li, C.; Nathanielsz, P. W.; Cox, L. A.
10.1101/2020.12.01.406355 — genomics — Posted on 2020-12-02
3913 Cumulative impacts across Australia's Great Barrier Reef: A mechanistic evaluation
Bozec, Y.-M.; Hock, K.; Mason, R. A. B.; Baird, M. E.; Castro-Sanguino, C.; Condie, S. A.; Puotinen, M.; Thompson, A.; Mumby, P. J.
10.1101/2020.12.01.406413 — ecology — Posted on 2020-12-02
3917 Host-environment interplay shapes fungal diversity in mosquitoes
Tawidian, P.; Coon, K. L.; Jumpponen, A.; Cohnstaedt, L. W.; Michel, K.
10.1101/2020.12.01.407494 — microbiology — Posted on 2020-12-02
3922 Decision value signals in the ventromedial prefrontal cortex and anhedonia across mood and psychotic disorders
Kang, M. S.; Wolf, D.; Kazinka, R.; Lee, S.; Ruparel, K.; Elliott, M.; Baldassano, C.; Xu, A.; Cieslak, M.; Prettyman, G.; Satterthwaite, T.; Kable, J.
10.1101/2020.12.01.407197 — neuroscience — Posted on 2020-12-02
3925 Retinotopic organization of visual cortex in human infants
Ellis, C. T.; Yates, T. S.; Skalaban, L. J.; Bejjanki, V. R.; Arcaro, M. J.; Turk-Browne, N. B.
10.1101/2020.12.01.407437 — neuroscience — Posted on 2020-12-02
3929 Single-Cell Manifold Preserving Feature Selection (SCMER)
Liang, S.; Mohanty, V.; Dou, J.; Miao, Q.; Huang, Y.; Muftuoglu, M.; Ding, L.; Peng, W.; Chen, K.
10.1101/2020.12.01.407262 — bioinformatics — Posted on 2020-12-02
3931 RUNX1 controls the dynamics of cell cycle entry of naive resting B cells by regulating expression of cell cycle and immunomodulatory genes in response to BCR stimulation
Thomsen, I.; Kunowska, N.; de Souza, R.; Moody, A.-M.; Crawford, G.; Wang, Y.-F.; Khadayate, S.; Strid, J.; Karimi, M. M.; Barr, A.; Dillon, N.; Sabbattini, P.
10.1101/2020.12.01.406744 — immunology — Posted on 2020-12-02
3932 HLA-E restricted, HIV-1 suppressing, Gag specific CD8+ T cells offer universal vaccine opportunities
Yang, H.; Rei, M.; Brackenridge, S.; Brenna, E.; Sun, H.; abdulhaqq, s.; Liu, M. K.; Ma, W.; Kurupati, P.; Xu, x.; Cerundolo, V.; Jenkins, E.; Davis, S. J.; Sacha, J. B.; Frueh, K.; Picker, L. J.; Borrow, P.; Gillespie, G.; McMichael, A. J.
10.1101/2020.12.01.406066 — immunology — Posted on 2020-12-02
3933 Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas
Ma, F.; Hughes, T. K.; Teles, R. M. B.; Andrade, P. R.; Silva, B. J. d. A.; Plazyo, O.; Tsoi, L. C.; Do, T.; Wadsworth, M. H.; Oulee, A.; Ochoa, M. T.; Sarno, E. N.; Iruela-Arispe, M. L.; Bryson, B.; Shalek, A. K.; Bloom, B. R.; Gudjonsson, J. E.; Pellegrini, M.; Modlin, R. L.
10.1101/2020.12.01.406819 — immunology — Posted on 2020-12-02
3936 Active and machine learning-based approaches to rapidly enhance microbial chemical production
Kumar, P.; Adamczyk, P.; Zhang, X.; Bonela, R.; Ramanathan, P.; Romero, P. A.; Reed, J.
10.1101/2020.12.01.406439 — systems biology — Posted on 2020-12-02
3937 The blast pathogen effector AVR-Pik binds and stabilizes rice heavy metal-associated (HMA) proteins to co-opt their function in immunity
Oikawa, K.; Fujisaki, K.; Shimizu, M.; Takeda, T.; Saitoh, H.; Hirabuchi, A.; Hiraka, Y.; Białas, A.; Langner, T.; Kellner, R.; Bozkurt, T. O.; Cesari, S.; Kroj, T.; Maidment, J.; Banfield, M. J.; Kamoun, S.; Terauchi, R.
10.1101/2020.12.01.406389 — plant biology — Posted on 2020-12-02
3938 Spatiotemporal Dynamics of Intra-tumoral Dependence on NEK2-EZH2 Signaling in Glioblastoma Cancer Progression
Wang, J.; Pavlyukov, M. S.; Yamashita, D.; Cheng, P.; Zhang, Z.; Kim, S.-H.; Nakano, M. A.; Xie, W.; Chen, D.; Frett, B.; Hu, W.-h.; Shin, Y. J.; Lee, Y.; Goidts, V.; Nam, D.-H.; Li, H.-y.; Nakano, I.
10.1101/2020.12.01.405696 — cancer biology — Posted on 2020-12-02
3939 Deep immune profiling reveals targetable mechanisms of immune evasion in checkpoint blockade-refractory glioblastoma
Simonds, E. F.; Lu, E. D.; Liu, E. V.; Tamaki, W.; Rancan, C.; Stultz, J.; Sinha, M.; McHenry, L. K.; Nasholm, N. M.; Chuntova, P.; Sundstrom, A.; Genoud, V.; Shahani, S. A.; Wang, L. D.; brown, c.; Walker, P. R.; Swartling, F. J.; Fong, L.; Okada, H.; Weiss, W. A.; Hellstrom, M.
10.1101/2020.12.01.404939 — cancer biology — Posted on 2020-12-02
3940 Oncostreams: Self-organization and dynamics determine spatial heterogeneity and malignant behavior in gliomas
Comba, A.; Motsch, S.; Dunn, P. J.; Hollon, T. C.; Zamler, D. B.; Argento, A. E.; Kleer, C. G.; Castro, M. G.; Lowenstein, P. R.
10.1101/2020.12.01.404970 — cancer biology — Posted on 2020-12-02
3946 Vaginal Microbiome Topic Modelling of Laboring Ugandan Women With and Without Fever
Movassagh, M.; Bebell, L. M.; Burgoine, K. L.; Hehnly, C.; Zhang, L.; Moran, K.; Sheldon, K.; Sinnar, S. A.; Kabachelor, E.; Bazira, J.; Kumbakumba, E.; Ochora, M.; Mulondo, R.; Nsubuga, B. K.; Weeks, A. D.; Gladstone, M. J.; Olupot-Olupot, P.; Ngonzi, J.; Roberts, D.; Meier, F. A.; Irizarry, R. A.; Broach, J. R.; Schiff, S. J.; Paulson, J. N.
10.1101/2020.12.01.401703 — genomics — Posted on 2020-12-02
3951 Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation
Angerilli, A.; Tait, J.; Berges, J.; Shcherbakova, I.; Schauer, T.; Smialowski, P.; Hsam, O.; Mentele, E.; Nicetto, D.; Rupp, R. A. W.
10.1101/2020.12.01.404053 — developmental biology — Posted on 2020-12-02
3952 Profiling of extracellular small RNAs highlights a strong bias towards non-vesicular secretion
Sork, H.; Conceicao, M.; Corso, G.; Nordin, J.; Lee, Y. X. F.; Krjutskov, K.; Westholm, J. O.; Vader, P.; Pauwels, M.; Vandenbroucke, R.; Wood, M. J.; Andaloussi, S. E.; Mäger, I.
10.1101/2020.12.01.406207 — molecular biology — Posted on 2020-12-02
3953 Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19
Formiga, R. O.; Amaral, F. C.; Souza, C. F.; Mendes, D. A. G. B.; Wanderley, C. W. S.; Lorenzini, C. B.; Santos, A. A.; Antonia, J.; Faria, L. F.; Natale, C. C.; Paula, N. M.; Silva, P. C. S.; Fonseca, F. R.; Aires, L.; Heck, N.; Starick, M. R.; Barroso, S. P. C.; Morrot, A.; Van Weyenbergh, J.; Sordi, R.; Alisson-Silva, F.; Mansur, D. S.; Cunha, F. Q.; Lummertz da Rocha, E.; Maurici, R.; Bafica, A.; Macauley, M. S.; Spiller, F.
10.1101/2020.11.12.379115 — immunology — Posted on 2020-12-02
3954 Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor
Godsel, L. M.; Roth-Carter, Q. R.; Koetsier, J. L.; Tsoi, L. C.; Broussard, J. A.; Fitz, G. N.; Lloyd, S. M.; Kweon, J.; Huffine, A. L.; Burks, H. E.; Hegazy, M.; Amagai, S.; Harms, P. W.; Johnson, J. L.; Urciuoli, G.; Doglio, L. T.; Swindell, W. R.; Awatramani, R.; Sprecher, E.; Bao, X.; Cohen-Barak, E.; Missero, C.; Gudjonsson, J. E.; Green, K. J.
10.1101/2020.12.01.406587 — immunology — Posted on 2020-12-02
3955 Neuroprotective mechanisms of red clover and soy isoflavones in Parkinson's disease models
de Rus Jacquet, A.; Ambaw, A.; Tambe, M. A.; Timmers, M.; Ma, S. Y.; Wu, Q.-L.; Simon, J. E.; McCabe, G. P.; Lila, M. A.; Shi, R.; Rochet, J.-C.
10.1101/2020.12.01.391268 — pharmacology and toxicology — Posted on 2020-12-02
3962 Spatial population genomics of a recent mosquito invasion
Schmidt, T. L.; Swan, T.; Chung, J.; Karl, S.; Demok, S.; Yang, Q.; Field, M. A.; Muzari, M. O.; Ehlers, G.; Brugh, M.; Bellwood, R.; Horne, P.; Burkot, T. R.; Ritchie, S.; Hoffmann, A. A.
10.1101/2020.11.30.405191 — genomics — Posted on 2020-12-02
3963 Cholesterol metabolism is a potential therapeutic target in Duchenne Muscular Dystrophy
Amor, F.; VuHong, A.; Corre, G.; Sanson, M.; Suel, L.; Blaie, S.; Servais, L.; Voit, T.; Richard, I.; Israeli, D.
10.1101/2020.12.01.405910 — genetics — Posted on 2020-12-02
3965 Cryptic β-lactamase evolution is driven by low β-lactam concentrations
Frohlich, C.; Gama, J. A.; Harms, K.; Hirvonen, V. H. A.; Lund, B. A.; van der Kamp, M. W.; Johnsen, P. J.; Samuelsen, O.; Leiros, H.-K. S.
10.1101/2020.12.01.404343 — evolutionary biology — Posted on 2020-12-02
3967 Estimating the breeding population of an elephant seal colony from a single census
Condit, R.; Allen, S. G.; Costa, D. P.; Codde, S.; Goley, P. D.; Le Boeuf, B. J.; Lowry, M. S.; Morris, P.
10.1101/2020.12.01.368605 — ecology — Posted on 2020-12-02
3969 Scalable production of tissue-like vascularised liver organoids from human PSCs.
Harrison, S. P.; Sillar, R.; Tanaka, Y.; Xiang, Y.; Patterson, B.; Kempf, H.; Melum, E.; Asrud, K.; Chollet, M. E.; Andersen, E.; Sandset, P. M.; Baumgarten, S.; Bonanini, F.; Kurek, D.; Mathapati, S.; Almaas, R.; Sharma, K.; Wilson, S. R.; Skottvoll, F. S.; Boger, I. C.; Bogen, I. L.; Nyman, T. A.; Wu, J. J.; Bezrouk, A.; Cizkova, D.; Mokry, J.; Zweigerdt, R.; Park, I.-H.; Sullivan, G. J.
10.1101/2020.12.02.406835 — cell biology — Posted on 2020-12-02
3970 Dietary protein increases T cell independent sIgA production through changes in gut microbiota-derived extracellular vesicles
Tan, J.; Ni, D.; Taitz, J.; Pinget, G.; Read, M.; Senior, A.; Wali, J.; Nanan, R.; King, N.; Grau, G.; Simpson, S.; Macia, L.
10.1101/2020.11.30.405217 — immunology — Posted on 2020-12-02
3971 Molecular characterization of projection neuron subtypes in the mouse olfactory bulb
Zeppilli, S.; Ackels, T.; Attey, R.; Klimpert, N.; Boeing, S.; Crombach, A.; Schaefer, A.; Fleischmann, A.
10.1101/2020.11.30.405571 — neuroscience — Posted on 2020-12-02
3973 Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling
Vasavda, C.; Semenza, E. R.; Liew, J.; Kothari, R.; Dhindsa, R. S.; Shanmukha, S.; Ricco, C.; Tokhunts, R.; Snowman, A. M.; Albacarys, L. K.; Paul, B. D.; Snyder, S. H.
10.1101/2020.12.01.405720 — neuroscience — Posted on 2020-12-02
3974 Acetylcholine as a trigger of the somatic exocytosis in Retzius neurons
Kazakova, T. A.; Suchalko, O. N.; Ivanov, A. D.; Alova, A. V.; Maksimov, G. V.
10.1101/2020.12.01.405951 — neuroscience — Posted on 2020-12-02
3975 Integrated multi-omics analysis reveals common and distinct dysregulated pathways for genetic subtypes of Frontotemporal Dementia
Menden, K.; Francescatto, M.; Niyma, T.; Blauwendraat, C.; Dhingra, A.; Castilla Lizardo, M.; Fernandes, N.; Kaurani, L.; Kronenberg-Versteeg, D.; Atarsu, B.; Sadikoglou, E.; Borroni, B.; Rodriguez Nieto, S.; Simon Sanchez, J.; Fischer, A.; Craig, D. W.; Neumann, M.; Bonn, S.; Rizzu, P.; Heutink, P.
10.1101/2020.12.01.405894 — neuroscience — Posted on 2020-12-02
3976 Multimodal-Multisensory Experiments: Design and Implementation
Razavi, M.; Yamauchi, T.; Janfaza, V.; Leontyev, A.; Longmire-Monford, S.; Orr, J. M.
10.1101/2020.12.01.405795 — neuroscience — Posted on 2020-12-02
3985 A data harmonization pipeline to leverage external controls and boost power in GWAS
Chen, D.; Tashman, K.; Palmer, D. S.; Neale, B.; Roeder, K.; Bloemendal, A.; Churchhouse, C.; Ke, Z. T.
10.1101/2020.11.30.405415 — genetics — Posted on 2020-12-02
3986 eSCAN: Scan Regulatory Regions for Aggregate Association Testing using Whole Genome Sequencing Data
Yang, Y.; Yang, Y.; Huang, L.; Broome, J. G.; Correa, A.; Reiner, A. P.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Raffield, L. M.; Li, Y.
10.1101/2020.11.30.405266 — genetics — Posted on 2020-12-02
3987 To the canopy and beyond: Air samples reveal wind dispersal as a driver of ubiquitous protistan pathogen assembly in tree canopies
Jauss, R.-T.; Nowack, A.; Walden, S.; Wolf, R.; Schaffer, S.; Schellbach, B.; Bonkowski, M.; Schlegel, M.
10.1101/2020.11.30.405688 — ecology — Posted on 2020-12-02
3989 FGF2 disruption enhances thermogenesis in brown and beige fat to protect against obesity and hepatic steatosis
Li, H.; Zhang, X.; Huang, C.; Liu, H.; Liu, S.; Zhang, Q.; Dong, M.; Hou, M.; Liu, Y.; Lin, H.
10.1101/2020.12.02.407650 — cell biology — Posted on 2020-12-02
3994 Membrane cholesterol regulates TRPV4 function, cytoskeletal expression and the cellular response to tension
Lakk, M.; Hoffmann, G. E.; Gorusupudi, A.; Bernstein, P.; Toft-Bertelsen, T. L.; MacAulay, N.; Krizaj, D.
10.1101/2020.12.01.406850 — cell biology — Posted on 2020-12-02
3995 Deep learning enables rapid and robust analysis of fluorescence lifetime imaging in photon-starved conditions
Yeh, H.-C.; Chen, Y.-I.; Chang, Y.-J.; Liao, S.-C.; Nguyen, T. D.; Yang, J.; Kuo, Y.-A.; Hong, S.; Liu, Y.-L.; Rylander, H. G.; Santacruz, S. R.; Yankeelov, T. E.
10.1101/2020.12.02.408195 — cell biology — Posted on 2020-12-02
3996 Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast
Turner, R.; Harrison, P. F.; Swaminathan, A.; Kraupner-Taylor, C. A.; Goldie, B. J.; See, M. M.; Peterson, A.; Schittenhelm, R. B.; Powell, D.; Creek, D. J.; Dichtl, B.; Beilharz, T.
10.1101/2020.12.01.407171 — cell biology — Posted on 2020-12-02
3997 Micro RNAs are minor constituents of extracellular vesicles and are hardly delivered to target cells
Albanese, M.; Chen, Y.-F. A.; Huels, C.; Gaertner, K.; Tagawa, T.; Mejias-Perez, E.; Keppler, O. T.; Goebel, C.; Zeidler, R.; Shein, M.; Schuetz, A. K.; Hammerschmidt, W.
10.1101/2020.05.20.106393 — cell biology — Posted on 2020-12-02
4000 Recruited macrophages that colonise the post-inflammatory peritoneal niche convert into functionally divergent resident cells
Louwe, P. A.; Badiola-Gomez, L.; Webster, H.; Perona-Wright, G.; Bain, C. C.; Forbes, S. J.; Jenkins, S. J.
10.1101/2020.11.30.404988 — immunology — Posted on 2020-12-02
4001 Enhancing daily light exposure increases the antibody response to influenza vaccination in patients with dementia
Munch, M.; Goldbach, R.; Zumstein, N.; Vonmoos, P.; Scartezzini, J.-L.; Wirz-Justice, A.; Cajochen, C.
10.1101/2020.11.30.405175 — immunology — Posted on 2020-12-02
4003 β-cell SENP1 facilitates responsiveness to incretins and limits oral glucose intolerance in high fat fed mice
Lin, H.; Smith, N.; Spigelman, A. F.; Suzuki, K.; Ferdaoussi, M.; Jin, Y.; Bautista, A.; Wang, Y. W.; Manning Fox, J. E.; Buteau, J.; MacDonald, P. E.
10.1101/2020.11.30.402644 — physiology — Posted on 2020-12-02
4008 Evidence for both phylogenetic conservatism and lability in the evolution of secondary chemistry in a tropical angiosperm radiation
Uckele, K. A.; Jahner, J. P.; Tepe, E. J.; Richards, L. A.; Dyer, L. A.; Ochsenrider, K. M.; Philbin, C. S.; Kato, M. J.; Yamaguchi, L. F.; Forister, M. L.; Smilanich, A. M.; Dodson, C. D.; Jeffrey, C. S.; Parchman, T. L.
10.1101/2020.11.30.404855 — evolutionary biology — Posted on 2020-12-02
4010 Novel TREM2 splicing isoform that lacks the V-set immunoglobulin domain is abundant in the human brain
Kiianitsa, K.; Kurtz, I.; Beeman, N.; Matsushita, M.; Chien, W.-M.; Raskind, W. H.; Korvatska, O.
10.1101/2020.11.30.404897 — immunology — Posted on 2020-12-02
4014 Bi-directional Modeling Between Cross-Scale Neural Activity
Chang, Y.-J.; Chen, Y.-I.; Yeh, H.-C.; Carmena, J. M.; Santacruz, S. R.
10.1101/2020.11.30.404244 — neuroscience — Posted on 2020-12-02
4015 White matter alterations in glaucoma and vision-deprived brains differ outside the visual system
Hanekamp, S.; Curcic-Blake, B.; Caron, B.; McPherson, B.; Timmer, A.; Prins, D.; Boucard, C. C.; Yoshida, M.; Ida, M.; Jansonius, N. M.; Pestilli, F.; Cornelissen, F. W.
10.1101/2020.11.30.404434 — neuroscience — Posted on 2020-12-02
4016 A theoretical framework for the site-specific and frequency-dependent neuronal effects of deep brain stimulation
Milosevic, L.; Kalia, S. K.; Hodaie, M.; Lozano, A. M.; Popovic, M. R.; Hutchison, W. D.; Lankarany, M.
10.1101/2020.11.30.404269 — neuroscience — Posted on 2020-12-02
4019 Freely behaving mice can brake and turn during optogenetic stimulation of the Mesencephalic Locomotor Region
van der Zouwen, C. I.; Boutin, J.; Fougere, M.; Flaive, A.; Vivancos, M.; Santuz, A.; Akay, T.; Sarret, P.; Ryczko, D.
10.1101/2020.11.30.404525 — neuroscience — Posted on 2020-12-02
4020 Methods for analysing lineage tracing datasets
Kostiou, V.; Zhang, H.; Hall, M. W. J.; Jones, P. H.; Hall, B. A.
10.1101/2020.01.11.901819 — systems biology — Posted on 2020-12-02
4021 Elucidating the short and long-term mechanical response of the cell nucleus with a hybrid viscoelastic model
Perez-Calixto, D.; Gonzalez-Villa, E.; Jimenez-Diaz, E.; Serna-Marquez, N.; Vazquez-Victorio, G.; Hautefeuille, M.
10.1101/542274 — biophysics — Posted on 2020-12-02
4022 DIscBIO: a user-friendly pipeline for biomarker discovery in single-cell transcriptomics
Ghannoum, S.; Leoncio Netto, W.; Fantini, D.; Ragan-Kelley, B.; Parizadeh, A.; Jonasson, E.; Stahlberg, A.; Farhan, H.; Kohn-Luque, A.
10.1101/700989 — bioinformatics — Posted on 2020-12-02
4027 Prenatal Methadone Exposure Disrupts Behavioral Development and Alters Motor Neuron Intrinsic Properties and Local Circuitry
Grecco, G. G.; Mork, B.; Huang, J.-Y.; Metzger, C. E.; Haggerty, D. L.; Reeves, K. C.; Gao, Y.; Hoffman, H.; Katner, S. N.; Masters, A. R.; Morris, C. W.; Newell, E. A.; Engleman, E. A.; Baucum, A. J.; Kim, J.; Yamamoto, B. K.; Allen, M. R.; Wu, Y.-C.; Lu, H.-C.; Sheets, P. L.; Atwood, B. K.
10.1101/2020.09.25.314013 — neuroscience — Posted on 2020-12-02
4029 Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer
Chan, J. M.; Quintanal-Villalonga, A.; Gao, V.; Xie, Y.; Allaj, V.; Chaudhary, O.; Masilionis, I.; Egger, J.; Chow, A.; Walle, T.; Mattar, M.; Yarlagadda, D. V.; Wang, J. L.; Uddin, F.; Offin, M.; Ciampricotti, M.; Bhanot, U. K.; Lai, W. V.; Bott, M. J.; Jones, D. R.; Ruiz, A.; Hollmann, T.; Poirier, J. T.; Nawy, T.; Mazutis, L.; Sen, T.; Pe'er, D.; Rudin, C. M.
10.1101/2020.12.01.406363 — cancer biology — Posted on 2020-12-02
4033 A Genetic Screen for Temperature-sensitive Morphogenesis-defective Caenorhabditis elegans Mutants
Jud, M. C.; Lowry, J.; Padilla, T.; Clifford, E.; Yang, Y.; Fennell, F.; Miller, A.; Hamill, D.; Harvey, A. M.; Avila-Zavala, M.; Shao, H.; Tran, N. N.; Bao, Z.; Bowerman, B.
10.1101/2020.12.01.407221 — genetics — Posted on 2020-12-02
4034 Interactive Web-based Annotation of Plant MicroRNAs with iwa-miRNA
Zhang, T.; Zhai, J.; Zhang, X.; Ling, L.; Li, M.; Xie, S.; Song, M.; Ma, C.
10.1101/2020.12.01.405399 — plant biology — Posted on 2020-12-02
4038 Chemical exhaustion of RPA in cancer treatment
VanderVere-Carozza, P. S.; Pawelczak, K. S.; Gavande, N. S.; Jalal, S. I.; Pollok, K. E.; Ekinci, E.; Heyza, J.; Patrick, S. M.; Turchi, J. J.
10.1101/2020.11.30.404640 — cancer biology — Posted on 2020-12-02
4041 Synergistic stabilization of a double mutant in CI2 from an in-cell library screen
Hamborg, L.; Granata, D.; Olsen, J. G.; Roche, J. V.; Pedersen, L. E.; Nielsen, A. T.; Lindorff-Larsen, K.; Teilum, K.
10.1101/2020.12.01.406082 — biophysics — Posted on 2020-12-02
4043 Viral Packaging ATPases Utilize a Glutamate Switch to Couple ATPase Activity and DNA Translocation
Pajak, J.; Atz, R.; Hilbert, B. J.; Morais, M.; Kelch, B. A.; Jardine, P.; Arya, G.
10.1101/2020.12.01.406595 — biophysics — Posted on 2020-12-02
4045 Assembly principles and stoichiometry of a complete human kinetochore module
Walstein, K.; Petrovic, A.; Pan, D.; Hagemeier, B.; Vogt, D.; Vetter, I. R.; Musacchio, A.
10.1101/2020.12.01.407130 — biochemistry — Posted on 2020-12-02
4047 Disease related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveals a path to selective inhibitors
Rathinaswamy, M. K.; Gaieb, Z.; Fleming, K. D.; Borsari, C.; Harris, N. J.; Moeller, B. J.; Wymann, M. P.; Amaro, R. E.; Burke, J. E.
10.1101/2020.12.01.406264 — biochemistry — Posted on 2020-12-02
4048 Glycan-Protein Interactions Determine Kinetics of N-Glycan Remodeling
Mathew, C.; Weiss, G.; Giese, C.; Lin, C.-W.; Losfeld, M.-E.; Glockshuber, R.; Riniker, S. Z.; Aebi, M.
10.1101/2020.12.01.406371 — biochemistry — Posted on 2020-12-02
4049 Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation
Lavictoire, S. J.; Jomaa, D.; Gont, A.; Jardine, K.; Cook, D. P.; Lorimer, I. A. J.
10.1101/2020.12.01.406538 — biochemistry — Posted on 2020-12-02
4051 Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in lipid composition in Gammarus fossarum
Fu, T.; Knittelfelder, O.; Geffard, O.; Clement, Y.; Testet, E.; Elie, N.; Touboul, D.; Abbaci, K.; Shevchenko, A.; Lemoine, J.; Chaumot, A.; Salvador, A.; Degli-Esposti, D.; Ayciriex, S.
10.1101/2020.12.01.368563 — biochemistry — Posted on 2020-12-02
4052 A C. elegans genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle function
Chaya, T.; Patel, S.; Smith, E. M.; Lam, A.; Miller, E. N.; Clupper, M.; Kervin, K.; Tanis, J. E.
10.1101/2020.12.01.407213 — genetics — Posted on 2020-12-02
4053 GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate
Song, M.; Yuan, X.; Racioppi, C.; Leslie, M.; Aleksandrova, A.; Christiaen, L.; Wilson, M. D.; Scott, I. C.
10.1101/2020.12.01.406140 — developmental biology — Posted on 2020-12-02
4054 Adaptive cell invasion maintains organ homeostasis
Peloggia, J.; Münch, D.; Meneses-Giles, P.; Romero-Carvajal, A.; McClain, M.; Pan, Y. A.; Piotrowski, T.
10.1101/2020.12.01.404954 — developmental biology — Posted on 2020-12-02
4055 The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice lightsheet microscopy
Quinn, S. E.; Huang, L.; Kerkvliet, J. G.; Swanson, J. A.; Smith, S.; Hoppe, A. D.; Anderson, R. B.; Thiex, N. W.; Scott, B. L.
10.1101/2020.12.01.390195 — cell biology — Posted on 2020-12-02
4057 Freeze-frame imaging of dendritic calcium signals with TubuTag
Perez-Alvarez, A.; Huhn, F.; Duerst, C. D.; Franzelin, A.; Lamothe-Molina, P.; Oertner, T. G.
10.1101/2020.11.30.403311 — neuroscience — Posted on 2020-12-02
4058 Versatile labeling and detection ofendogenous proteins using tag-assistedsplit enzyme complementation
Makhija, S.; Brown, D.; Bourke, S.; Wang, Y.; Zhou, S.; Rudlaff, R.; Cheloor-Kovilakam, R.; Huang, B.
10.1101/2020.12.01.407072 — bioengineering — Posted on 2020-12-02
4059 Mapping the human auditory cortex using spectrotemporal receptive fields generated with magnetoencephalography
Falet, J.-P. R.; Cote, J.; Tarka, V.; Martinez-Moreno, Z.-E.; Voss, P.; de Villers-Sidani, E.
10.1101/2020.12.01.406843 — neuroscience — Posted on 2020-12-02
4060 A comprehensive catalogue of regulatory variants in the cattle transcriptome
Liu, S.; Gao, Y.; Canela-Xandri, O.; Wang, S.; Yu, Y.; Cai, W.; Li, B.; Pairo-Castineira, E.; D'Mellow, K.; Rawlik, K.; Xia, C.; Yao, Y.; Li, X.; Yan, Z.; Li, C.; Rosen, B. D.; Van Tassell, C. P.; Vanraden, P. M.; Zhang, S.; Ma, L.; Cole, J. B.; Liu, G. E.; Tenesa, A.; Fang, L.
10.1101/2020.12.01.406280 — genomics — Posted on 2020-12-02
4064 Parallel Hippocampal-Parietal Circuits for Self- and Goal-oriented Processing
Zheng, A.; Montez, D. F.; Marek, S.; Gilmore, A.; Newbold, D. J.; Laumann, T. O.; Kay, B. P.; Seider, N. A.; Van, A. N.; Hampton, J. M.; Alexopolous, D.; Schlaggar, B. L.; Sylvester, C. M.; Greene, D. J.; Shimony, J. S.; Nelson, S. M.; Wig, G. S.; Gratton, C.; McDermott, K. B.; Raichle, M. E.; Gordon, E. M.; Dosenbach, N. U.
10.1101/2020.12.01.395210 — neuroscience — Posted on 2020-12-02
4065 Coastal winds drive a recruitment mechanism for estuarine fisheries
Schilling, H. T.; Hinchliffe, C.; Gillson, J. P.; Miskiewicz, A.; Suthers, I. M.
10.1101/2020.06.24.170068 — ecology — Posted on 2020-12-01
4072 From Value to Saliency: Neural Computations of Subjective Value under Uncertainty in PTSD
Jia, R.; Ruderman, L.; Gordon, C.; Ehrlich, D.; Horvath, M.; Mirchandani, S.; DeFontes, C.; Southwick, S.; Krystal, J. H.; Harpaz-Rotem, I.; Levy, I.
10.1101/2020.04.14.041467 — neuroscience — Posted on 2020-12-01
4074 Multimodal Single-Cell Omics Analysis of COVID-19 Sex Differences in Human Immune Systems
Hou, Y.; Zhou, Y.; Gack, M.; Lathia, J.; Kallianpur, A.; Mehra, R.; Chan, T.; Jung, J. U.; Jehi, L.; Eng, C.; Cheng, F.
10.1101/2020.12.01.407007 — systems biology — Posted on 2020-12-01
4076 Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
Ordonez, L. D.; Melchor, L.; Greenow, K. R.; Kendrick, H.; Tornillo, G.; Bradford, J.; Giles, P.; Smalley, M. J.
10.1101/2020.10.30.361998 — cancer biology — Posted on 2020-12-01
4077 Targeting C5aR1 Increases the Therapeutic Window of Radiotherapy
Olcina, M. M.; Melemenidis, S.; Nambiar, D. K.; Kim, R. K.; Casey, K. M.; von Eyben, R.; Woodruff, T. M.; Graves, E. G.; Le, Q.-T.; Stucki, M.; Giaccia, A. J.
10.1101/2020.10.27.358036 — cancer biology — Posted on 2020-12-01
4083 Mucosal Associated Invariant T (MAIT) Cell Responses Differ by Sex in COVID-19
Yu, C.; Littleton, S.; Giroux, N.; Mathew, R.; Ding, S.; Kalnitsky, J.; Petzold, E.; Chung, H.; Palomino, G. r.; Rotstein, T.; Xi, R.; Ko, E. R.; Tsalik, E. L.; sempowski, g.; Denny, T. N.; Burke, T. W.; McClain, M. T.; Woods, C. W.; Shen, X.; Saban, D. R.
10.1101/2020.12.01.407148 — immunology — Posted on 2020-12-01
4085 The Drosophila Baramicin polypeptide gene protects against fungal infection
Hanson, M. A.; Cohen, L. B.; Marra, A.; Iatsenko, I.; Wasserman, S. A.; Lemaitre, B.
10.1101/2020.11.23.394148 — immunology — Posted on 2020-12-01
4086 The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling
Zhang, S.; Wang, Y.; Zhu, X.; Song, L.; Ma, E.; McDonough, J.; Fu, H.; Cambi, F.; Grinspan, J.; Guo, F.
10.1101/2020.09.16.300624 — neuroscience — Posted on 2020-12-01
4088 Nutrient signaling pathways regulate amyloid clearance and synaptic loss in Alzheimer's disease
Mondal, M.; Bali, J.; Tzioras, M.; Paolicelli, R. C.; Jawaid, A.; Malnar, M.; Dominko, K.; Udayar, V.; Ben Halima, S.; Vadodaria, K. C.; Manesso, E.; Thakur, G.; Decressac, M.; Petit, C.; Sudharshan, R.; Hecimovic, S.; Simons, M.; Klumperman, J.; Bruestle, O.; Ferguson, S.; Nitsch, R.; Schulz, P. E.; Spires-Jones, T. L.; Koch, P.; Gunawan, R.; Rajendran, L.
10.1101/2020.11.13.381186 — neuroscience — Posted on 2020-12-01
4089 Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer
Chan, J. M.; Quintanal-Villalonga, A.; Gao, V.; Xie, Y.; Allaj, V.; Chaudhary, O.; Masilionis, I.; Egger, J.; Chow, A.; Walle, T.; Mattar, M.; Yarlagadda, D. V.; Wang, J. L.; Offin, M.; Ciampricotti, M.; Bhanot, U. K.; Lai, W. V.; Bott, M. J.; Jones, D. R.; Ruiz, A.; Hollmann, T.; Poirier, J. T.; Nawy, T.; Mazutis, L.; Sen, T.; Pe'er, D.; Rudin, C. M.
10.1101/2020.12.01.406363 — cancer biology — Posted on 2020-12-01
4094 Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
Ijäs, H.; Shen, B.; Heuer-Jungemann, A.; Keller, A.; Kostiainen, M. A.; Liedl, T.; Ihalainen, J. A.; Linko, V.
10.1101/2020.05.13.088054 — biochemistry — Posted on 2020-12-01
4095 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
Chen, X.; Ali, Y.; Fisher, C. E. L.; Arribas-Bosacoma, R.; Rajasekaran, M. B.; Williams, G.; Walker, S.; Booth, J. R.; Hudson, J. J. R.; Roe, S. M.; Pearl, L. H.; Ward, S. E.; Pearl, F. M. G.; Oliver, A. W.
10.1101/2020.11.30.403493 — biochemistry — Posted on 2020-12-01
4097 Strengthening The Organizing and Reporting of Microbiome Studies (STORMS)
Mirzayi, C. A.; Renson, A.; Zohra, F.; Elsafoury, S.; Geistlinger, L.; Kasselman, L.; Eckenrode, K.; van de Wijgert, J. H.; Loughman, A.; Marques, F.; STORMS Consortium, ; Genomic Standards Consortium, ; Massive Analysis and Quality Control Society, ; Segata, N.; Beghini, F.; Huttenhower, C.; Dowd, J. B.; Jones, H.; Waldron, L. D.
10.1101/2020.06.24.167353 — genomics — Posted on 2020-12-01
4098 Leveraging supervised learning for functionally-informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs
Wang, Q. S.; Kelley, D. R.; Ulirsch, J.; Kanai, M.; Sadhuka, S.; Cui, R.; Albors, C.; Cheng, N.; Okada, Y.; The Biobank Japan Project, ; Aguet, F.; Ardlie, K. G.; MacArthur, D. G.; Finucane, H. K.
10.1101/2020.10.20.347294 — genomics — Posted on 2020-12-01
4102 Disentangling interactions among mercury, immunity, and infection in a Neotropical bat community
Becker, D.; Speer, K.; Korstian, J.; Volokhov, D.; Droke, H.; Brown, A.; Baijnauth, C.; Padgett-Stewart, T.; Broders, H.; Plowright, R.; Rainwater, T.; Fenton, M. B.; Simmons, N.; Chumchal, M.
10.1101/2020.06.12.135475 — ecology — Posted on 2020-12-01
4104 Mechanical competition alters the cellular interpretation of an endogenous genetic programme
Bhide, S.; Gombalova, D.; Mönke, G.; Stegmaier, J.; Zinchenko, V.; Kreshuk, A.; Belmonte, J. M.; Leptin, M.
10.1101/2020.10.15.333963 — developmental biology — Posted on 2020-12-01
4105 The Erythropoietin Receptor Stimulates Rapid Cycling and Formation of Larger Red Cells During Mouse and Human Erythropoiesis
Hidalgo, D.; Bejder, J.; Pop, R.; Gellatly, K.; Scalf, S. M.; Eastman, A. E.; Chen, J.-J.; Zhu, L. J.; Heuberger, J. A. A. C.; Guo, S.; Koury, M. J.; Nordsborg, N. B.; Socolovsky, M.
10.1101/2020.11.30.404780 — developmental biology — Posted on 2020-12-01
4106 Differential integrin adhesome expression defines human natural killer cell residency and developmental stage
Hegewisch Solloa, E.; Seo, S.; Mundy-Bosse, B. L.; Mishra, A.; Waldman, E.; Maurrasse, S.; Grunstein, E.; Connors, T. J.; Freud, A. G.; Mace, E. M.
10.1101/2020.12.01.404806 — cell biology — Posted on 2020-12-01
4108 Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic
Lubin, J. H.; Zardecki, C.; Dolan, E. M.; Lu, C.; Shen, Z.; Dutta, S.; Westbrook, J. D.; Hudson, B. P.; Goodsell, D. S.; Williams, J. K.; Voigt, M.; Sarma, V.; Xie, L.; Venkatachalam, T.; Arnold, S.; Alfaro Alvarado, L. H.; Catalfano, K.; Khan, A.; McCarthy, E.; Staggers, S.; Tinsley, B.; Trudeau, A.; Singh, J.; Whitmore, L.; Zheng, H.; Benedek, M.; Currier, J.; Dresel, M.; Duvvuru, A.; Dyszel, B.; Fingar, E.; Hennen, E. M.; Kirsch, M.; Khan, A. A.; Labrie-Cleary, C.; Laporte, S.; Lenkeit, E.; Martin, K.; Orellana, M.; Ortiz-Alvarez de la Campa, M.; Paredes, I.; Wheeler, B.; Rupert, A.; Sam, A
10.1101/2020.12.01.406637 — molecular biology — Posted on 2020-12-01
4111 Deciphering the scopolamine challenge rat model by preclinical functional MRI
Somogyi, G.; Hlatky, D.; Spisak, T.; Spisak, Z.; Nyitrai, G.; Czurko, A.
10.1101/2020.04.08.031534 — neuroscience — Posted on 2020-12-01
4112 The Filter Detection Task for measurement of breathing-related interoception and metacognition
Harrison, O. K.; Garfinkel, S. N.; Marlow, L.; Finnegan, S.; Marino, S.; Nanz, L.; Allen, M.; Finnemann, J.; Keur-Huizinga, L.; Harrison, S. J.; Stephan, K. E.; Pattinson, K. T.; Fleming, S. M.
10.1101/2020.06.29.176941 — neuroscience — Posted on 2020-12-01
4115 Population Level Variation of Transposable Elements in a Maize Diversity Panel
O'Connor, C.; Qiu, Y.; Della Coletta, R.; Renk, J. S.; Monnahan, P.; Noshay, J. M.; Lang, Z.; Gilbert, A.; Anderson, S. N.; McGaugh, S. E.; Springer, N. M.; Hirsch, C.
10.1101/2020.09.25.314401 — plant biology — Posted on 2020-12-01
4116 Designed proteins assemble antibodies into modular nanocages
Divine, R.; Dang, H. V.; Ueda, G.; Fallas, J. A.; Vulovic, I.; Sheffler, W.; Saini, S.; Zhao, Y. T.; Raj, I. X.; Morawski, P. A.; Jennewein, M. F.; Homad, L. J.; Wan, Y.-H.; Tooley, M. R.; Seeger, F.; Fahning, M. L.; Etemadi, A.; Lazarovits, J.; Roederer, A.; Walls, A. C.; Stewart, L.; Mazloomi, M.; King, N. P.; Campbell, D. J.; McGuire, A. T.; Stamatatos, L.; Ruohola-Baker, H.; Mathieu, J.; Veesler, D.; Baker, D.
10.1101/2020.12.01.406611 — biochemistry — Posted on 2020-12-01
4118 Exchange of molecular and cellular information: a hybrid model that integrates stem cell divisions and key regulatory interactions
Van den Broeck, L.; Spurney, R.; Fisher, A.; Schwartz, M.; Clark, N.; Nguyen, T.; Madison, I.; Gobble, M.; Long, T.; Sozzani, R.
10.1101/2020.11.30.404426 — developmental biology — Posted on 2020-12-01
4120 Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.
Ho, J. S. Y.; Mok, B. W.-Y.; Campisi, L.; Jordan, T.; Yildiz, S.; Parameswaran, S.; Wayman, J. A.; Gaudreault, N. N.; Meekins, D. A.; Indran, S. V.; Morozov, I.; Trujillo, J. D.; Fstkchyan, Y. S.; Rathnasinghe, R.; Zhu, Z.; Zheng, S.; Zhao, N.; White, K.; Ray-Jones, H.; Malysheva, V.; Thiecke, M. J.; Lau, S.-Y.; Liu, H.; Zhang, A. J.; Lee, A. C.-Y.; Liu, W.-C.; Aydillo, T.; Melo, B. S.; Guccione, E.; Sebra, R.; Shum, E.; Bakker, J.; Kaufman, D. A.; Moreira, A.; Carossino, M.; Balasuriya, U. B. R.; Byun, M.; Miraldi, E. R.; Albrecht, R. A.; Schotsaert, M.; Garcia-Sastre, A.; Chanda, S. K.; Jeya
10.1101/2020.12.01.404483 — microbiology — Posted on 2020-12-01
4121 A pomegranate peel extract as inhibitor of SARS-CoV-2 Spike binding to human ACE2 (in vitro): a promising source of novel antiviral drugs
Tito, A.; Colantuono, A.; Pirone, L.; Pedone, E. M.; Intartaglia, D.; Giamundo, G.; Conte, I.; Vitaglione, P.; Apone, F.
10.1101/2020.12.01.406116 — microbiology — Posted on 2020-12-01
4122 Differential effects of antiseptic mouth rinses on SARS-CoV-2 infectivity in vitro
Xu, C.; Wang, A.; Hoskin, E. R.; Cugini, C.; Markowitz, K.; Chang, T. L.; Fine, D. H.
10.1101/2020.12.01.405662 — microbiology — Posted on 2020-12-01
4123 PKR and the Integrated Stress Response drive immunopathology caused by ADAR1 mutation
Maurano, M.; Snyder, J. M.; Connelly, C.; Henao-Mejia, J.; Sidrauski, C.; Stetson, D. B.
10.1101/2020.11.30.405498 — immunology — Posted on 2020-12-01
4124 Neutrophil and monocyte dysfunctional effector response towards bacterial challenge in critically-ill COVID-19 patients
Mairpady Shambat, S.; Gomez-Mejia, A.; Schweizer, T. A.; Huemer, M.; Chang, C.-C.; Acevedo, C.; Bergada Pijuan, J.; Vulin, C.; Miroshnikova, N.; Hofmanner, D. A.; Wendel Garcia, P. D.; Hilty, M. P.; Buehler, P. K.; Schuepbach, R. A.; Brugger, S. D.; Zinkernagel, A. S.
10.1101/2020.12.01.406306 — immunology — Posted on 2020-12-01
4125 A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens
Stevenson, A. J.; McCartney, D. L.; Shireby, G. L.; Hillary, R. F.; King, D.; Tzioras, M.; Wrobel, N.; McCafferty, S.; Murphy, L.; McColl, B. W.; Redmond, P.; Taylor, A. M.; Harris, S. E.; Russ, T. C.; Hannon, E. J.; McIntosh, A. M.; Mill, J.; Smith, C.; Deary, I. J.; Cox, S. R.; Marioni, R. E.; Spires-Jones, T. L.
10.1101/2020.11.30.404228 — neuroscience — Posted on 2020-12-01
4126 Strain- and age-dependent features of the nigro-striatal circuit in three common laboratory mouse strains, C57BL/6J, A/J, and DBA/2J - Implications for Parkinson's disease modeling
Thomas, M. H.; Karout, M.; Pardo Rodriguez, B.; Gui, Y. H.; Jaeger, C.; Michelucci, A.; Kollmus, H.; Schughart, K.; Coowar, D.; Balling, R.; Mittelbronn, M.; Sinkkonen, L.; Garcia, P.; Buttini, M.
10.1101/2020.11.30.404293 — neuroscience — Posted on 2020-12-01
4128 Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations
Li, J. V.; Ng, C. A.; Cheng, D.; Yao, M.; Guo, Y.; Yu, Z.-Y.; Ramaswamy, Y.; Ju, L. A.; Kuchel, P. W.; Feneley, M. P.; Fatkin, D.; Cox, C. D.
10.1101/2020.11.30.404962 — biophysics — Posted on 2020-12-01
4130 Balanced Functional Module Detection in Genomic Data
Tritchler, D.; Towle-Miller, L. M.; Miecznikowski, J. C.
10.1101/2020.11.30.404038 — bioinformatics — Posted on 2020-12-01
4132 3D Genome Contributes to Protein-Protein Interactome
Shi, Y.; Cao, S.; Zhang, M.; Su, X.; Guo, Z.; Wang, J.; Liu, T.; Shi, H.; He, G.
10.1101/2020.11.30.404517 — bioinformatics — Posted on 2020-12-01
4133 Major diversification of caribou shaped by glacial cycles before the Last Glacial Maximum
Taylor, R. S.; Manseau, M.; Klutsch, C. F. C.; Polfus, J. L.; Steedman, A.; Hervieux, D.; Kelly, A.; Larter, N. C.; Gamberg, M.; Schwantje, H.; Wilson, P. J.
10.1101/2020.11.30.404731 — evolutionary biology — Posted on 2020-12-01
4135 The ecology of Nipah virus in Bangladesh: a nexus of land use change and opportunistic feeding behavior in bats
McKee, C. D.; Islam, A.; Luby, S. P.; Salje, H.; Hudson, P. J.; Plowright, R. K.; Gurley, E. S.
10.1101/2020.11.30.404582 — ecology — Posted on 2020-12-01
4138 Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo
Simonetti, F. R.; Zhang, H.; Soroosh, G. P.; Duan, J.; Rhodehouse, K.; Hill, A. L.; Beg, S. A.; McCormick, K.; Raymond, H.; Nobles, C. L.; Everett, J.; Kwon, K. J.; White, J. A.; Lai, J.; Margolick, J. B.; Hoh, R.; Deeks, S. G.; Bushman, F. D.; Siliciano, J. D.; Siliciano, R. F.
10.1101/2020.12.01.402651 — microbiology — Posted on 2020-12-01
4142 Transcriptome analysis for the development of cell-type specific labeling to study olfactory circuits
Koldaeva, A.; Zhang, C.; Huang, Y.-P.; Reinert, J. K.; Mizuno, S.; Sugiyama, F.; Takahashi, S.; Soliman, T.; Matsunami, H.; Fukunaga, I.
10.1101/2020.11.30.403865 — neuroscience — Posted on 2020-12-01
4144 InsectBrainDatabase - A unified platform to manage, share, and archive morphological and functional data
Heinze, S.; el Jundi, B.; Berg, B. G.; Homberg, U.; Menzel, R.; Pfeiffer, K.; Dacke, M.; Warrant, E. J.; Pfuhl, G.; Rybak, J.; Tedore, K.
10.1101/2020.11.30.397489 — neuroscience — Posted on 2020-12-01
4149 Multiple variants of the blast fungus effector AVR-Pik bind the HMA domain of the rice protein OsHIPP19 with high affinity.
Maidment, J. H. R.; Franceschetti, M.; Maqbool, A.; Saitoh, H.; Jantasuriyarat, C.; Kamoun, S.; Terauchi, R.; Banfield, M. J.
10.1101/2020.12.01.403451 — plant biology — Posted on 2020-12-01
4150 Comparative Analysis of Embryo Proper and Suspensor Transcriptomes in Plant Embryos With Different Morphologies
Goldberg, R.; Chen, M.; Lin, J.-Y.; Wu, X.; Apuya, N. R.; Henry, K. F.; Le, B. H.; Bui, A. Q.; Pelletier, J. M.; Cokus, S.; Pellegrini, M.; Harada, J. J.
10.1101/2020.11.30.404376 — plant biology — Posted on 2020-12-01
4151 Arabidopsis Casein Kinase 2 triggers Stem Cell Exhaustion under Al Toxicity and Phosphate Deficiency Through activation of the DNA Damage Response pathway
Pengliang, W.; Demulder, M.; David, P.; Eekhout, T.; Yoshiyama, K. O.; Nguyen, L.; Vercauteren, I.; Eeckhout, D.; Galle, M.; De Jaeger, G.; Larsen, P.; Audenaert, D.; Desnos, T.; Nussaume, L.; Loris, R.; De Veylder, L.
10.1101/2020.11.30.404459 — plant biology — Posted on 2020-12-01
4152 DIETARY MONOTERPENOIDS AS A NEW CLASS OF ALLOSTERIC HUMAN ARYL HYDROCARBON RECEPTOR ANTAGONISTS
Poulikova, K.; Zuvalova, I.; Vyhlidalova, B.; Krasulova, K.; Jiskrova, E.; Vrzal, R.; Kortagere, S.; Kopecna, M.; Kopecny, D.; Sebela, M.; Rolfes, K. M.; Haarmann-Stemmann, T.; Mani, S.; Dvorak, Z.
10.1101/2020.11.30.404178 — pharmacology and toxicology — Posted on 2020-12-01
4153 Optimized chemogenomic library design strategies for precision oncology
Athanasiadis, P.; Ravikumar, B.; Carragher, N. O.; Clemons, P. A.; Johanssen, T.; Ebner, D.; Aittokallio, T.
10.1101/2020.11.30.403329 — cancer biology — Posted on 2020-12-01
4157 Effects of maternal deprivation and complex housing on pro-social behavior in rats: An automated, operant task examining motivation to liberate a trapped conspecific
Kalamari, A.; Kentrop, J.; Hinna Danesi, C.; Graat, E. J. M.; van IJzendoorn, M. H.; Bakermans-Kranenburg, M. J.; Joels, M.; van der Veen, R.
10.1101/2020.11.30.403386 — animal behavior and cognition — Posted on 2020-12-01
4158 A body map of somatic mutagenesis in morphologically normal human tissues
Li, R.; Di, L.; Li, J.; Fan, W.; Liu, Y.; Guo, W.; Liu, W.; Liu, L.; Li, Q.; Chen, L.; Chen, Y.; Miao, C.; Liu, H.; Wang, Y.; Ma, Y.; Xu, D.; Lin, D.; Huang, Y.; Wang, J.; Bai, F.; Wu, C.
10.1101/2020.11.30.403436 — genomics — Posted on 2020-12-01
4159 Large uncertainty in individual PRS estimation impacts PRS-based risk stratification
Ding, Y.; Hou, K.; Burch, K. S.; Lapinska, S.; Prive, F.; Vilhjalmsson, B. J.; Sankararaman, S.; Pasaniuc, B.
10.1101/2020.11.30.403188 — genomics — Posted on 2020-12-01
4162 Pollen source richness may be a poor predictor of bumblebee colony growth
Watrobska, C.; Ramos Rodrigues, A.; Arce, A.; Clarke, J.; Gill, R. J.
10.1101/2020.11.30.403444 — ecology — Posted on 2020-12-01
4163 An experimental assessment of the distribution of environmental DNA along the water column
Agostinis, A. O.; Dal Pont, G.; Borio, A.; Horodesky, A.; Bertao, A. P. S.; Netto, O. S. M.; Zanin, T. L.; Ostrensky, A.; Pie, M. R.
10.1101/2020.11.30.402438 — ecology — Posted on 2020-12-01
4165 Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH
Stadhouders, L. E.; Verbrugge, S. A.; Smith, J. A.; Gabriel, B. M.; Hammersen, T. D.; Kolijn, D.; Vogel, I. S.; Mohamed, A. M.; De Wit, G. M.; Offringa, C.; Hoogaars, W. M.; Gehlert, S.; Wackerhage, H.; Jaspers, R. T.
10.1101/2020.12.01.403949 — molecular biology — Posted on 2020-12-01
4167 Streptococcus agalactiae MprF synthesizes a novel cationic glycolipid that promotes brain entry and meningitis
Joyce, L. R.; Manzer, H. S.; da C. Mendonca, J.; Villarreal, R.; Doran, K. S.; Palmer, K. L.; Guan, Z.
10.1101/2020.12.01.406702 — microbiology — Posted on 2020-12-01
4168 African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques
Crooks, C. M.; Weiler, A. M.; Rybarczyk, S. L.; Bliss, M. I.; Jaeger, A. S.; Murphy, M. E.; Simmons, H. A.; Mejia, A.; Fritsch, M. K.; Hayes, J. M.; Eickhoff, J. C.; Mitzey, A. M.; Razo, E.; Braun, K.; Brown, E. A.; Yamamoto, K.; Shepard, P. M.; Possell, A.; Weaver, K.; Antony, K. M.; Morgan, T. K.; Dudley, D.; Peterson, E.; Schultz-Darken, N.; O'Connor, D. H.; Mohr, E. L.; Golos, T. G.; Aliota, M.; Friedrich, T. C.
10.1101/2020.11.30.405670 — microbiology — Posted on 2020-12-01
4169 Chlamydia gallinacea: genetically armed as a pathogen however a phenotypical commensal?
Heijne, M.; Jelocnik, M.; Umanets, A.; Brouwer, M. S.; Dinkla, A.; Harders, F.; van Keulen, L. J.; Roest, H. J.; Schaafsma, F.; velkers, F. C.; van der Goot, J. A.; Pannekoek, Y.; Koets, A. P.
10.1101/2020.11.30.405704 — microbiology — Posted on 2020-12-01
4171 Mechanisms of antibody binding revealed by asymmetric Fab-virus complexes
Goetschius, D. J.; Hartmann, S. R.; Organtini, L. J.; Callaway, H.; Huang, K.; Bator, C. M.; Ashley, R. E.; Makhov, A. M.; Conway, J. F.; Parrish, C. R.; Hafenstein, S. L.
10.1101/2020.12.01.406983 — microbiology — Posted on 2020-12-01
4174 Large Neutral Amino acid uptake and mTOR activation within CD4+ T cells coordinate Type 2 immunity and host resistance to Trichuris muris
Krauss, M. Z.; Hayes, K. S.; Villegas-Mendez, A.; Hepworth, M. R.; Sinclair, L. V.; Couper, K. N.; Grencis, R. K.
10.1101/2020.11.30.405316 — immunology — Posted on 2020-12-01
4177 Liquid foam therapy (LiFT) for homogenous distribution of exogenous pulmonary surfactant in ARDS
Fishler, R.; Ostrovski, Y.; Frenkel, A.; Dorfman, S.; Brod, V.; Haas, T.; Waisman, D.; Sznitman, J.
10.1101/2020.11.30.403337 — pharmacology and toxicology — Posted on 2020-12-01
4179 Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice
Smith, C. M.; Baker, R. E.; Proulx, M. K.; Mishra, B. B.; Long, J. E.; Park, S. W.; Lee, H.-N.; Kiritsy, M. C.; Bellerose, M. M.; Olive, A. J.; Murphy, K. C.; Papavinasasundaram, K.; Boehm, F. J.; Reames, C. J.; Meade, R. K.; Hampton, B. K.; Linnertz, C.; Ehrt, S.; Schnappinger, D.; Pardo-Manuel de Villena, F.; Ferris, M. T.; Ioerger, T. R.; Sassetti, C. M.
10.1101/2020.12.01.405514 — genetics — Posted on 2020-12-01
4182 Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
Starr, T. N.; Greaney, A. J.; Addetia, A.; Hannon, W. H.; Choudhary, M. C.; Dingens, A. S.; Li, J. Z.; Bloom, J. D.
10.1101/2020.11.30.405472 — microbiology — Posted on 2020-12-01
4183 The metalloproteinase inhibitor Prinomastat reduces AML growth,prevents stem cell loss and improves chemotherapy effectiveness
Pirillo, C.; Haltalli, M.; Gonzalez Anton, S.; Tini, V.; Kong, I.; Hawkins, E.; Falini, B.; Marra, A.; Duarte, D.; Lo Celso, C.
10.1101/2020.12.01.393157 — cancer biology — Posted on 2020-12-01
4186 Transcriptional regulation profiling reveals disrupted lipid metabolism in failing hearts with a pathogenic phospholamban mutation
Pei, J.; Maas, R. G. C.; Nagyova, E.; Gho, J. M. I. H.; Snijders Blok, C.; van Adrichem, I.; Calis, J. J. A.; van Es, R.; Sepehrkhouy, S.; Feyen, D.; van den Dungen, N.; Lansu, N.; de Jonge, N.; den Ruijter, H. M.; Huibers, M. M. H.; de Weger, R. A.; van Laake, L. W.; Verhaar, M. C.; van Tintelen, P.; van Steenbeek, F. G.; van Mil, A.; Buikema, J. W.; Burgering, B.; Kararikes, I.; Mercola, M.; Doevendans, P. A.; Sluijter, J.; Vink, A.; Cheng, C.; Mokry, M.; Asselbergs, F. W.; Harakalova, M.
10.1101/2020.11.30.402792 — genomics — Posted on 2020-12-01
4187 Guidelines for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples
Kubik, S.; Marques, A. C.; Xing, X.; Silvery, J.; Bertelli, C.; De Maio, F.; Pournaras, S.; Burr, T.; Duffourd, Y.; Siemens, H.; Alloui, C.; Song, L.; Wenger, Y.; Saitta, A.; Macheret, M.; Smith, E. W.; Menu, P.; Brayer, M.; Steinmetz, L. M.; Si-Mohammed, A.; Chuisseu, J.; Stevens, R.; Constantoulakis, P.; Sali, M.; Greub, G.; Tiemann, C.; Pelechano, V.; Willig, A.; Xu, Z.
10.1101/2020.12.01.405738 — genomics — Posted on 2020-12-01
4189 Ste20-like kinase is critical for inhibitory synapse maintenance and its deficiency confers a developmental dendritopathy
Schoch, S.; Quatraccioni, A.; Robens, B. K.; Maresch, R.; van Loo, K. M. J.; Kelly, T.; Opitz, T.; Borger, V.; Dietrich, D.; Pitsch, J.; Beck, H.; Becker, A. J.
10.1101/2020.11.30.393132 — neuroscience — Posted on 2020-12-01
4190 Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer
Chan, J. M.; Quintanal-Villalonga, A.; Gao, V.; Xie, Y.; Allaj, V.; Chaudhary, O.; Masilionis, I.; Egger, J.; Chow, A.; Walle, T.; Mattar, M.; Yarlagadda, D. V.; Wang, J. L.; Offin, M.; Ciampricotti, M.; Bhanot, U. K.; Lai, W. V.; Bott, M. J.; Jones, D. R.; Ruiz, A.; Hollmann, T.; Poirier, J. T.; Nawy, T.; Mazutis, L.; Sen, T.; Pe'er, D.; Rudin, C. M.
10.1101/2020.12.01.406363 — cancer biology — Posted on 2020-12-01
4191 Investigating the role of APOE: limitations of human pluripotent stem cell-derived cerebral organoids
Hernandez, D.; Rooney, L. A.; Daniszewski, M.; Gulluyan, L.; Liang, H. H.; Cook, A.; Hewitt, A.; Pebay, A.
10.1101/2020.11.30.405654 — neuroscience — Posted on 2020-12-01
4192 Convergence of Heteromodal Lexical Retrieval in the Lateral Prefrontal Cortex
Aabedi, A. A.; Kakaizada, S.; Young, J. S.; Wiese, O.; Valdivia, C.; Berger, M. S.; Weissman, D. H.; Brang, D.; Hervey-Jumper, S. L.
10.1101/2020.11.30.405746 — neuroscience — Posted on 2020-12-01
4193 A scientometric overview of CORD-19
Colavizza, G.; Costas, R.; Traag, V. A.; van Eck, N. J.; van Leeuwen, T.; Waltman, L.
10.1101/2020.04.20.046144 — scientific communication and education — Posted on 2020-12-01
4195 Neutralization of SARS-CoV-2 and zoonotic coronavirus threats by mosaic nanoparticle vaccination
Cohen, A. A.; Gnanapragasam, P. N. P.; Lee, Y. E.; Ou, S.; Kakutani, L. M.; Keeffe, J. R.; Barnes, C. O.; Wu, H.-J.; Howarth, M.; West, A. P.; Nussenzweig, M. C.; Bjorkman, P. J.
10.1101/2020.11.17.387092 — immunology — Posted on 2020-12-01
4196 Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium
Baxter, B. D.; Larson, E. D.; Merle, L.; Feinstein, P.; Polese, A. G.; Bubak, A. N.; Niemeyer, C. S.; Shepherd, D.; Ramakrishnan, V. R.; Nagel, M. A.; Restrepo, D.
10.1101/2020.05.14.096016 — neuroscience — Posted on 2020-12-01
4200 u-track 3D: measuring and interrogating intracellular dynamics in three dimensions.
Roudot, P.; Legant, W. R.; Zou, Q.; Dean, K. M.; Welf, E. S.; David, A. F.; Gerlich, D. W.; Fiolka, R. P.; Betzig, E.; Danuser, G.
10.1101/2020.11.30.404814 — cell biology — Posted on 2020-12-01
4201 Lipid Droplets Promote Phase Separation of Ago2 to Accelerate Dicer1 Loss and Decelerate miRNA Activity in Lipid Exposed Hepatic Cells
Bandopadhyay, D.; Basu, S.; Mukherjee, I.; Chakraborty, R.; Mukherjee, K.; Chattopadhyay, K.; Chakrabarti, S.; Chakrabarti, P.; Bhattacharyya, S. N.
10.1101/2020.11.30.405449 — cell biology — Posted on 2020-12-01
4202 Controlling Cellular Arrangements via Stretched Bioprinting
He, C.; Liu, M.; Jiang, D.; Qin, C.; Liang, T.; Wu, P.; Han, C.; Huang, L.; Hsia, K. J.; Wang, P.
10.1101/2020.11.30.403378 — cell biology — Posted on 2020-12-01
4203 Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.
Katz, M.; Subramaniam, S.; Chomsky-Hecht, O.; Tsemakhovich, V.; Belkacemi, A.; Flockerzi, V.; Klussmann, E.; Hirsch, J.; Weiss, S.; Dascal, N.
10.1101/2020.11.30.403964 — physiology — Posted on 2020-12-01
4205 Muscle specific translational control of Cand2 by mTORC1 regulates adverse cardiac remodeling
Gorska, A.; Sandmann, C.; Riechert, E.; Hofmann, C.; Malovrh, E.; Varma, E.; Kmietczyk, V.; Juergensen, L.; Kamuf-Schenk, V.; Stroh, C.; Furkel, J.; Konstandin, M.; Sticht, C.; Boileau, E.; Dieterich, C.; Katus, H. A.; Doroudgar, S.; Völkers, M.
10.1101/2020.11.29.403196 — molecular biology — Posted on 2020-12-01
4206 Metabolic selection of a homologous recombination mediated loss of glycosomal fumarate reductase in Trypanosoma brucei
wargnies, M.; Plazolles, N.; Schenk, R.; Villafraz, O.; Dupuy, J.-W.; Biran, M.; Bachmaier, S.; Baudouin, H.; Clayton, C.; Boshart, M.; Bringaud, F.
10.1101/2020.11.29.403048 — microbiology — Posted on 2020-12-01
4208 Can citizen science analysis of camera trap data be used to study reproduction? Lessons from Snapshot Serengeti program
Thel, L.; Chamaille-Jammes, S.; Keurinck, L.; Catala, M.; Packer, C.; Huebner, S.; Bonenfant, C.
10.1101/2020.11.30.400804 — ecology — Posted on 2020-12-01
4211 Scaffold pore geometry guides gene regulation and bone-like tissue formation in dynamic cultures
Rubert, M.; Vetsch, J. R.; Lehtoviita, I.; Sommer, M.; Zhao, F.; Studart, A. R.; Mueller, R.; Hofmann, S.
10.1101/2020.04.24.060525 — bioengineering — Posted on 2020-12-01
4213 Improved growth and morphological plasticity of Haloferax volcanii
de Silva, R. T.; Abdul Halim, M. F.; Pittrich, D. A.; Brown, H. J.; Pohlschroder, M.; Duggin, I. G.
10.1101/2020.05.04.078048 — microbiology — Posted on 2020-12-01
4214 Competition for electrons favors N2O reduction in denitrifying Bradyrhizobium isolates
Gao, Y.; Mania, D.; Mousavi, S. A.; Lycus, P.; Arntzen, M. O.; Lindstrom, K.; Shapleigh, J. P.; Bakken, L. R.; Frostegard, A.
10.1101/2020.07.20.212696 — microbiology — Posted on 2020-12-01