bioRxiv directory

Cabral, L.; Calabro, F.; Rasmussen, J.; Foran, W.; Moore, L. A.; Graham, A.; O'Connor, T. G.; Wadhwa, P. D.; Entringer, S.; Fair, D.; Buss, C.; Panigrahy, A.; Luna, B.

10.1101/2023.06.30.547249 — neuroscience — Posted on 2023-06-30

3 A Citrullus genus super-pangenome reveals extensive variations in wild and cultivated watermelons and sheds light on watermelon evolution and domestication

Wu, S.; Sun, H.; Gao, L.; Branham, S.; McGregor, C.; Renner, S. S.; Xu, Y.; Kousik, C.; Wechter, P.; Levi, A.; Fei, Z.

10.1101/2023.06.08.544282 — plant biology — Posted on 2023-06-30

4 Machine learning of enhancer-promoter specificity based on enhancer perturbation studies reveals a distinct class of enhancers.

Barth, D.; Cardwell, J.; Han, M. V.

10.1101/2023.06.30.547290 — bioinformatics — Posted on 2023-06-30

5 Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample

Sandoval-Velasco, M.; Dudchenko, O.; Antonio Rodriguez, J.; Perez Estrada, C.; Dehasque, M.; Fontsere, C.; Mak, S. S. T.; Plotnikov, V.; Khan, R.; Weisz, D.; Contessoto, V. G.; Oliveira Junior, A. B.; Kalluchi, A.; Omer, A. D.; Batra, S. S.; Shamim, M. S.; Durand, N. C.; O'Connell, B.; Roca, A. L.; Gnirke, A.; Garcia-Trevino, I.; Coke, R.; Flanagan, J. P.; Pletch, K.; Ruiz-Herrera, A.; Lander, E. S.; Rowley, M. J.; Onuchic, J. N.; Dalen, L.; Marti-Renom, M. A.; Gilbert, M. T. P.; Aiden, E. L.

10.1101/2023.06.30.547175 — genomics — Posted on 2023-06-30

6 Transfer of modified fecal viromes alleviates symptoms of non-alcoholic liver disease and improve blood glucose regulation in an obesity mouse model

Mao, X.; Larsen, S. B.; Zachariassen, L. S. F.; Brunse, A.; Adamberg, S.; Castro-Mejia, J. L.; Adamberg, K.; Nielsen, D. S.; Hansen, A. K.; Hansen, C. H. F.; Rasmussen, T. S.

10.1101/2023.03.20.532903 — microbiology — Posted on 2023-06-30

7 Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils

Ravesloot-Chavez, M. M.; Van Dis, E.; Fox, D.; Nguyenla, X. H.; Rawal, S. L.; Ballinger, M. A.; Thomas, H.; Kotov, D. I.; Vance, R.; Nachman, M.; Stanley, S.

10.1101/2023.06.29.547125 — immunology — Posted on 2023-06-30

8 The successor representation subserves hierarchical abstraction for goal-directed behavior

Wientjes, S.; Holroyd, C. B.

10.1101/2023.06.30.547163 — neuroscience — Posted on 2023-06-30

9 Microbial Interactions from a New Perspective: Reinforcement Learning Reveals New Insights into Microbiome Evolution

Ghadermazi, P.; Chan, S. H. J.

10.1101/2023.05.07.539711 — systems biology — Posted on 2023-06-30

10 Automated Microbial Classification System based on Deep Convolutional Neural Networks using Images from Colony Picker

Park, S.; Yeoh, J. W.; Choo, C. T.; Lim, C. K.; Dao, V. L.; Poh, C. L.

10.1101/2023.06.29.547155 — synthetic biology — Posted on 2023-06-30

11 A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint

Sanchez, H.; Liu, Z.; van Veen, E.; van Laar, T.; Solano, B.; Diffley, J. F. X.; Dekker, N. H.

10.1101/2023.05.18.541303 — biophysics — Posted on 2023-06-30

12 Cardiac-Gated Spectroscopic Photoacoustic Imaging for Ablation-Induced Necrotic Lesion Visualization: In Vivo Demonstration in a Beating Heart

Gao, S.; Ashikaga, H.; Suzuki, M.; Mansi, T.; Kim, Y.-H.; Ghesu, F.-C.; Kang, J.; Boctor, E. M.; Halperin, H. R.; Zhang, H. K.

10.1101/2022.05.23.492682 — bioengineering — Posted on 2023-06-30

13 FruitFire: a luciferase based on a fruit fly metabolic enzyme

Adams, S. T.; Zephyr, J.; Bohn, M. F.; Schiffer, C. A.; Miller, S. C.

10.1101/2023.06.30.547126 — biochemistry — Posted on 2023-06-30

14 Machine learning reveals relationships between song, climate, and migration in coastal Zonotrichia leucophrys

Yang, J.; Carstens, B. C.; Provost, K. L.

10.1101/2023.03.08.531720 — evolutionary biology — Posted on 2023-06-30

15 Spatial variation in population genomic responses to over a century of anthropogenic change within a tidal marsh songbird

Benham, P.; Walsh, J.; Bowie, R. C. K.

10.1101/2022.06.10.495648 — evolutionary biology — Posted on 2023-06-30

16 Efficient Formation of Single-copy Human Artificial Chromosomes

Gambogi, C. W.; Mer, E.; Brown, D. M.; Yankson, G.; Gavade, J. N.; Logsdon, G. A.; Heun, P.; Glass, J. I.; Black, B. E.

10.1101/2023.06.30.547284 — molecular biology — Posted on 2023-06-30

17 Amazing structural diversity of giant virus-like particles in forest soil

Fischer, M. G.; Mersdorf, U.; Blanchard, J. L.

10.1101/2023.06.30.546935 — microbiology — Posted on 2023-06-30

18 Cross-species transmission and PB2 mammalian adaptations of highly pathogenic avian influenza A/H5N1 viruses in Chile

Pardo Roa, C.; Nelson, M.; Ariyama, N.; Aguayo, C.; Almonacid, L.; Munoz, G.; Navarro, C.; Avila, C.; Ulloa, M.; Reyes, R.; Fuentes Luppichini, E.; Mathieu, C.; Vergara, R.; Gonzalez, A.; Gonzalez, C. G.; Araya, H.; Fernandez, J.; Fasce, R.; Johow, M.; Medina, R. A.; Neira-Ramirez, V.

10.1101/2023.06.30.547205 — microbiology — Posted on 2023-06-30

19 Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse

Duvick, L.; Southern, W. M.; Benzow, K.; Handler, H. P.; Mitchell, J. S.; Kuivinen, H.; Gadiparthi, U. K.; Yang, P.; Soles, A.; Scheeler, C.; Rainwater, O.; Serres, S.; Lind, E.; Nichols-Meade, T.; You, Y.; Zoghbi, H. Y.; Ervasti, J. M.; Cvetanovic, M.; Koob, M. D.; Orr, H. T.; Zoe, B. N.; Wheeler, V. C.

10.1101/2023.02.08.527710 — neuroscience — Posted on 2023-06-30

20 Systemic Calcitonin Gene-Related Peptide (CGRP) modifies auditory and vestibular endorgan electrical potentials, and increases auditory and vestibular hypersensitivities: Implications for vestibular migraine

Rahman, S. M.; Liang, B.; Faucher, S.; Fine, E.; Jonnala, R.; Holt, J. C.; Lee, C.; Luebke, A. E.

10.1101/2022.06.03.494764 — neuroscience — Posted on 2023-06-30

21 Inferring causal connectivity from pairwise recordings and optogenetics

Lepperod, M. E.; Stöber, T. M.; Hafting, T.; Fyhn, M.; Kording, K. P.

10.1101/463760 — neuroscience — Posted on 2023-06-30

22 Can ChatGPT pass Glycobiology?

Ormsby Williams, D.; Fadda, E.

10.1101/2023.04.13.536705 — scientific communication and education — Posted on 2023-06-30

23 Compression algorithm for colored de Bruijn graphs

Rahman, A.; Dufresne, Y.; Medvedev, P.

10.1101/2023.05.12.540616 — bioinformatics — Posted on 2023-06-30

24 CellHeap: A scRNA-seq workflow for large-scalebioinformatics data analysis

Castro, M. C.; Silva, V. S.; Costa, M. O.; Silva, H. S.; Walter, M. E.; Melo, A.; Ocana, K.; dos Santos, M. T.; Nicolas, M. F.; Carvalho, A. C.; Pons, A. H.; Silva, F. A. B.

10.1101/2023.04.19.537508 — bioinformatics — Posted on 2023-06-30

25 Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders

Flores-Fernandez, J. M.; Pesch, V.; Sriraman, A.; Chimal-Juarez, E.; Amidian, S.; Wang, X.; Reithofer, S.; Ma, L.; Tamgueney, G.; Wille, H.

10.1101/2023.06.30.547254 — biochemistry — Posted on 2023-06-30

26 A Rationally Designed Antimicrobial Peptide from Structural and Functional Insight of Clostridium difficile Translation Initiation Factor 1

Alanis, E.; Aguilar, F.; Banaei, N.; Dean, F. B.; Alanis, M.; Bullard, J. M.; Zhang, Y.

10.1101/2023.06.30.547268 — biochemistry — Posted on 2023-06-30

27 Synthetic autotetraploid Caenorhabditis elegans resist severe cold stress by escaping cold induced death at the gravid adult stage.

Chauve, L.; McGarry, A.; Butler, L.; McLysaght, A.

10.1101/2023.06.28.546823 — cell biology — Posted on 2023-06-30

28 TREX reveals proteins that bind to specific RNA regions in living cells

Dodel, M.; Guiducci, G.; Dermit, M.; Krishnamurthy, S.; Stojic, L.; Mardakheh, F. K.

10.1101/2023.06.30.547259 — cell biology — Posted on 2023-06-30

29 HOXDeRNA activates a cancerous transcription program and super-enhancers genome-wide

Deforzh, E.; Kharel, P.; Karelin, A.; Ivanov, P.; Krichevsky, A. M.

10.1101/2023.06.30.547275 — molecular biology — Posted on 2023-06-30

30 A soft tick vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests

Bonsergent, C.; Vittecoq, M.; Leray, C.; Jouglin, M.; Buysse, M.; McCoy, K.; Malandrin, L.

10.1101/2023.03.24.534071 — microbiology — Posted on 2023-06-30

31 Carbon source and surface type influence the early-stage biofilm formation by rhizosphere bacterium Pseudomonas donghuensis P482.

Rajewska, M.; Maciag, T.; Jafra, S. J.

10.1101/2023.06.30.547207 — microbiology — Posted on 2023-06-30

32 Decomposing a San Francisco Estuary microbiome using long read metagenomics reveals species and species- and strain-level dominance from picoeukaryotes to viruses

Lui, L. M.; Nielsen, T. N.

10.1101/2023.06.30.547288 — microbiology — Posted on 2023-06-30

33 Pangenomes reveal genomic signatures of microbial adaptation to experimental soil warming

Choudoir, M. J.; Narayanan, A.; Rodriguez-Ramos, D.; Simoes, R.; Efroni, A.; Sondrini, A.; DeAngelis, K. M.

10.1101/2023.03.16.532972 — microbiology — Posted on 2023-06-30

34 Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus

Pruitt, E. L.; Zhang, R.; Ross, D. H.; Ashford, N. K.; Chen, X.; Alonzo, F.; Bush, M. F.; Werth, B. J.; Xu, L.

10.1101/2023.06.29.547085 — microbiology — Posted on 2023-06-30

35 Novel expression of major histocompatibility complex II in dorsal root ganglion neurons attenuates paclitaxel-induced cold hypersensitivity in male and female mice

Whitaker, E. E.; Mecum, N. E.; Cott, R. C.; Goode, D. J.

10.1101/2023.03.31.535136 — immunology — Posted on 2023-06-30

36 Reward sensitivity and corticostriatal function during social rewards

Wyngaarden, J. B.; Johnston, C. R.; Sazhin, D.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M.; Alloy, L. B.; Smith, D. V.; Jarcho, J. M.

10.1101/2023.01.17.524305 — neuroscience — Posted on 2023-06-30

37 Stimulus-specific enhancement of responses in mouse primary visual cortex mediated by GABA release from VIP cells

Kaneko, M.; Hoseini, M. S.; Waschek, J. A.; Stryker, M. P.

10.1101/2023.06.19.545641 — neuroscience — Posted on 2023-06-30

38 Trophoblast glycoprotein is required for efficient synaptic vesicle exocytosis from retinal rod bipolar cells.

Wakeham, C. M.; Shi, Q.; Ren, G.; Haley, T. L.; Duvoisin, R.; von Gersdorff, H.; Morgans, C. W.

10.1101/2022.07.25.501380 — neuroscience — Posted on 2023-06-30

39 The conserved Arabidopsis PM19L1 protein functions as an osmosensor and regulator of dormancy and germination

Alexander, R. D.; Castillejo-Pons, P.; Melzer, N.; Alsaif, O.; Strotmann, V. I.; Seale, M.; Stahl, Y.; Morris, P. C.

10.1101/2020.08.10.244889 — plant biology — Posted on 2023-06-30

40 Foveal RGCs develop abnormal calcium dynamics weeks after photoreceptor ablation

Xu, Z.; Kunala, K.; Murphy, P.; Puthussery, T.; McGregor, J. E.

10.1101/2023.05.30.542908 — physiology — Posted on 2023-06-30

41 Atomistic molecular simulations of Aβ-Zn conformational ensembles

Aduriz-Arrizabalaga, J.; Lopez, X.; De Sancho, D.

10.1101/2023.03.23.534009 — biophysics — Posted on 2023-06-30

42 How Myosin VI Traps its Off-State, is Activated and Dimerizes

Canon, L.; Kikuti, C.; Planelles-Herrero, V. J.; Lin, T.; Mayeux, F.; Sirkia, H.; Lee, Y. i.; Heidsieck, L.; Velikovsky, L.; David, A.; Liu, X.; Moussaoui, D.; Forest, E.; Hook, P.; Petersen, K. J.; Di Cicco, A.; Sires-Campos, J.; Levy, D.; Delevoye, C.; Sweeney, H. L.; Houdusse, A.

10.1101/2023.06.30.547185 — biochemistry — Posted on 2023-06-30

43 AlphaFold2 can predict single-mutation effects on structure and phenotype

Mcbride, J. M.; Reinharz, V.; Polev, K.; Grzybowski, B. A.; Tlusty, T.

10.1101/2022.04.14.488301 — biochemistry — Posted on 2023-06-30

44 Spontaneous helping in pigs is mediated by helper's social attention and distress signals of individuals in need

Moscovice, L. R.; Eggert, A.; Manteuffel, C.; Rault, J.-L.

10.1101/2023.03.17.533160 — animal behavior and cognition — Posted on 2023-06-30

45 A common flanking variant is associated with enhanced meiotic stability of the FGF14-SCA27B locus

Pellerin, D.; Del Gobbo, G.; Couse, M.; Dolzhenko, E.; Dicaire, M.-J.; Rebelo, A.; Roth, V.; Wandzel, M.; Bonnet, C.; Ashton, C.; Lamont, P. J.; Laing, N. G.; Renaud, M.; Ravenscroft, G.; Houlden, H.; Synofzik, M.; Eberle, M. A.; Boycott, K. M.; Pastinen, T.; All of Us Long Reads Working Group, ; Brais, B.; Zuchner, S.; Danzi, M. C.

10.1101/2023.05.11.540430 — genetics — Posted on 2023-06-30

46 Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition

Gao, C. W.; Lin, W.; Riddle, R. C.; Kushwaha, P.; Boukas, L.; Bjornsson, H. T.; Hansen, K. D.; Fahrner, J. A.

10.1101/2023.06.23.546270 — genetics — Posted on 2023-06-30

47 Transition to transversion ratio estimation by accounting codon degeneracy and pretermination codons in coding sequences

Beura, P. K.; Aziz, R.; Sen, P.; Das, S.; Namsa, N. D.; Feil, E.; Satapathy, S. S.; Ray, S. K.

10.1101/2022.11.03.515082 — evolutionary biology — Posted on 2023-06-30

48 Environmental constraints can explain clutch size differences between urban and forest blue tits: insights from an egg removal experiment

Pitt, M. D.; Capilla-Lasheras, P.; Alhowiti, N. S. S.; Branston, C. J.; Carlon, E.; Boonekamp, J. J.; Dominoni, D. M.

10.1101/2023.01.05.522710 — ecology — Posted on 2023-06-30

49 Agricultural drivers of field margin plant communities are scale dependent

Poinas, I.; Fried, G.; Henckel, L.; Meynard, C. N.

10.1101/2023.03.02.530797 — ecology — Posted on 2023-06-30

50 Host infection dynamics and disease induced mortality modify species contributions to the environmental reservoir

Laggan, N. A.; Parise, K. L.; White, J. P.; Kaarakka, H. M.; Redell, J. A.; DePue, J. E.; Scullon, W. H.; Kath, J.; Foster, J. T.; Kilpatrick, A. M.; Langwig, K. E.; Hoyt, J. R.

10.1101/2022.09.20.508714 — ecology — Posted on 2023-06-30

51 Centriolar subdistal appendages promote double strand break repair through homologous recombination

Prados-Carvajal, R.; Dominguez-Calvo, A.; Rodriguez-Real, G.; Bayona-Feliu, A.; Gomes-Pereira, S.; Balestra, F. R.; Huertas, P.

10.1101/2022.10.19.512819 — cell biology — Posted on 2023-06-30

52 Endocytic myosin-1 is a force-insensitive, power-generating motor

Pedersen, R. T.; Snoberger, A.; Pyrpassopoulos, S.; Safer, D.; Drubin, D. G.; Ostap, E. M.

10.1101/2023.03.21.533689 — cell biology — Posted on 2023-06-30

53 Cryo-electron tomography of large biological specimens vitrified by plunge freezing

Baeuerlein, F. J. B.; Renner, M.; El Chami, D.; Lehnart, S. E.; Pastor-Pareja, J. C.; Fernandez-Busnadiego, R.

10.1101/2021.04.14.437159 — cell biology — Posted on 2023-06-30

54 Co-translational ribosome pairing enables native assembly of misfolding-prone subunits

Wruck, F.; Schmitt, J.; Fenzl, K.; Bertolini, M.; Katranidis, A.; Bukau, B.; Kramer, G.; Tans, S.

10.1101/2023.06.30.547139 — molecular biology — Posted on 2023-06-30

55 Engineering transposon-associated TnpB-1 ωRNA system for efficient gene editing and disease treatment in mouse

Li, Z.; Guo, R.; Sun, X.; Li, G.; Liu, Y.; Huo, X.; Yang, R.; Shao, Z.; Zhang, H.; Zhang, W.; Zhang, X.; Ma, S.; Yao, Y.; Liu, X.; Yang, H.; Hu, C.; Zhou, Y.; Xu, C.

10.1101/2023.06.29.547137 — molecular biology — Posted on 2023-06-30

56 Chemogenetic profiling of ubiquitin-like modifier pathways identifies NFATC2IP as a mediator of SUMO-dependent genome integrity

Cho, T.; Zhao, Y.; Olivieri, M.; Hoeg, L.; Setiaputra, D.; Durocher, D.

10.1101/2023.06.30.547196 — molecular biology — Posted on 2023-06-30

57 Sub-communities of the vaginal ecosystem in pregnant and non-pregnant women.

Symul, L.; Jeganathan, P.; Costello, E.; France, M.; Bloom, S. M.; Ravel, J.; Kwon, D. S.; Relman, D. A.; Holmes, S. P.

10.1101/2021.12.10.471327 — microbiology — Posted on 2023-06-30

58 Wound microbiota-mediated correction of matrix metalloproteinase expression promotes re-epithelialization of diabetic wounds

White, E. K.; Uberoi, A.; Pan, J. T.-C.; Ort, J. T.; Campbell, A. E.; Murga-Garrido, S. M.; Harris, J. C.; Bhanap, P.; Wei, M.; Robles, N. Y.; Gardner, S. E.; Grice, E. A.

10.1101/2023.06.30.547263 — microbiology — Posted on 2023-06-30

59 Proteomic survey of the DNA damage response in Caulobacter crescentus

Tashjian, T. F.; Zeinert, R. D.; Eyles, S. J.; Chien, P.

10.1101/2023.03.24.534141 — microbiology — Posted on 2023-06-30

60 Shedding Light On Blue-Green Photosynthesis: A Wavelength-Dependent Mathematical Model Of Photosynthesis In Synechocystis sp. PCC 6803

Pfennig, T.; Kullmann, E.; Zavrel, T.; Nakielski, A.; Ebenhöh, O.; Cerveny, J.; Bernat, G.; Matuszynska, A. B.

10.1101/2023.06.30.547186 — plant biology — Posted on 2023-06-30

61 A Random Matrix Approach to Single Cell RNA-seq Analysis

Leviyang, S.

10.1101/2023.06.28.546922 — bioinformatics — Posted on 2023-06-30

62 Electron-counting in MicroED

Hattne, J.; Martynowycz, M.; Clabbers, M.; Gonen, T.

10.1101/2023.06.29.547123 — biochemistry — Posted on 2023-06-30

63 Solution structure, dynamics and tetrahedral assembly of Anti-TRAP, a homo-trimeric triskelion-shaped regulator of tryptophan biosynthesis in Bacillus subtilis

McElroy, C. A.; Ihms, E. C.; Kumar Yadav, D.; Holmquist, M.; Wadhwa, V.; Wysocki, V.; Gollnick, P.; Foster, M.

10.1101/2023.06.29.547145 — biochemistry — Posted on 2023-06-30

64 Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail

Sexton, J. A.; Potchernikov, T.; Sepulveda, G. C.; Cao, W.; Lou, H. J.; Boggon, T. J.; De La Cruz, E. M.; Turk, B. E.

10.1101/2023.06.30.547189 — molecular biology — Posted on 2023-06-30

65 Immunologically mediated trade-offs shaping transmission of sylvatic dengue and Zika viruses in native and novel non-human primate hosts

Hanley, K. A.; Cecilia, H.; Azar, S. R.; Moehn, B.; Yu, W.; Yun, R.; Althouse, B. M.; Vasilakis, N.; Rossi, S. L.

10.1101/2023.06.30.547187 — microbiology — Posted on 2023-06-30

66 Degradation of sulphonated mono and di-azo dye as the sole carbon source in Serratia marcescens: Insights from combined wet and dry lab analysis

Basharat, Z.; Yasmin, A.

10.1101/2023.06.30.547171 — microbiology — Posted on 2023-06-30

67 Bridges instead of boats? The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope core of phospholipid trafficking

BELOIN, C.; Grasekamp, K. P.; Beaud, B.; Taib, N.; Audrain, B.; Bardiaux, B.; Rossez, Y.; IZADI-PRUNEYRE, N.; Lejeune, M.; Trivelli, X.; Chouit, Z.; Guerardel, Y.; GHIGO, J.-M.; Gribaldo, S.

10.1101/2023.06.30.547184 — microbiology — Posted on 2023-06-30

68 Autoantibody subclass predominance is not driven by aberrant class switching or impaired B cell development

Paardekooper, L. M.; Fillie-Grijpma, Y. E.; van der Sluijs-Gelling, A. J.; Zlei, M.; van Doorn, R.; Vermeer, M. H.; Paunovic, M.; Titulaer, M. J.; van der Maarel, S. M.; van Dongen, J. J. M.; Verschuuren, J. J.; Huijbers, M. G.

10.1101/2023.06.30.546522 — immunology — Posted on 2023-06-30

69 Transferrin Receptor 1 is Required for CD4+ T Cell Iron-Dependent Response During Acute Toxoplasma gondii Infection

Denton, S. L.; Roy, T.; Akandawen, M.; Keplinger, H. K.; Ng, S. K.; Gigley, J. P.

10.1101/2023.06.28.546960 — immunology — Posted on 2023-06-30

Sghirripa, S.; Graetz, L.; Semmler, J. G.; Hanna, R.; Williams, E. E.; Goldsworthy, M. R.

10.1101/2023.06.28.546988 — neuroscience — Posted on 2023-06-30

71 Decision-consistent bias mediated by drift dynamics of human visual working memory

Gu, H.; Lee, J.; Kim, S.; Lim, J.; Lee, H.-J.; Lee, H.; Choe, M.; Yoo, D.-G.; Ryu, J. H. J.; Lim, S.; Lee, S.-H.

10.1101/2023.06.28.546818 — neuroscience — Posted on 2023-06-30

72 A frame and a hotspot in cochlear mechanics

Strimbu, C. E.; Chiriboga, L. A.; Frost, B. L.; Fallah, E.; Olson, E. S.

10.1101/2023.06.29.547111 — neuroscience — Posted on 2023-06-30

73 Fork in the road: how self-confidence about terrain influences gaze behaviour and path choice

da Eira Silva, V.; Marigold, D. S.

10.1101/2023.06.29.547105 — neuroscience — Posted on 2023-06-30

74 Perception of energy production from biomass: A Mexican population pilot survey

Angulo-Sherman, A. A.; Mascorro-Guzman, J. A.; Vasquez-Olmos, J. d. R.; Zuniga-Sanchez, O.; Monteros-Curiel, E.; Durand-Moreno, L. C.; Flores-Payan, V.

10.1101/2023.06.27.546801 — scientific communication and education — Posted on 2023-06-30

75 MicroRNA-122-mediated liver detargeting enhances the tissue specificity of cardiac genome editing

Yang, L.; Guo, C.; Liu, Z.; Chen, Z.; Sun, Y.; Hu, X.; Zheng, Y.; Li, Y.; Gao, F.; Zhou, P.; Pu, W. T.; Guo, Y.

10.1101/2023.06.29.546982 — physiology — Posted on 2023-06-30

76 Analytical Method Development for Evaluation of Pharmacokinetics and Tissue Distribution of Thiourea-Based Antivirals through nLC/MS-MS

Kumar, J.; Tyagi, P.; Saini, A. K.; Sharma, D.; Kumar, V.

10.1101/2023.06.28.546831 — pharmacology and toxicology — Posted on 2023-06-30

77 DrugGPT: A GPT-based Strategy for Designing Potential Ligands Targeting Specific Proteins

Li, Y.; Gao, C.; Song, X.; Wang, X.; Xu, Y.; Han, S.

10.1101/2023.06.29.543848 — bioinformatics — Posted on 2023-06-30

78 Non-covalent Linking Antibody to Yeast Using the Cell Surface Display of Staphylococcal Protein A

Shi, Y.-F.

10.1101/2023.06.30.547162 — bioengineering — Posted on 2023-06-30

79 Accounting for Isoform Expression in eQTL Mapping Substantially Increases Power

LaPierre, N.; Pimentel, H.

10.1101/2023.06.28.546921 — genetics — Posted on 2023-06-30

80 The draft genome of the microscopic Nemertoderma westbladi sheds light on the evolution of Acoelomorpha genomes

Abalde, S.; Tellgren-Roth, C.; Heintz, J.; Vinnere Pettersson, O.; Jondelius, U.

10.1101/2023.06.28.546832 — evolutionary biology — Posted on 2023-06-30

81 High germline mutation rates but not extreme population size outbreaks influence genetic diversity in crown-of-thorns sea stars

Popovic, I.; Bergeron, L.; Bozec, Y.-M.; Waldvogel, A.-M.; Howitt, S. M.; Damjanovic, K.; Patel, F.; Cabrera, M. G.; Wörheide, G.; Uthicke, S.; Riginos, C.

10.1101/2023.06.28.546961 — evolutionary biology — Posted on 2023-06-30

82 Hierarchical Classification of Insects with Multitask Learning and Anomaly Detection

Bjerge, K.; Geissmann, Q.; Alison, J.; Mann, H. M. R.; Hoye, T. T.; Dyrmann, M.; Karstoft, H.

10.1101/2023.06.29.546989 — ecology — Posted on 2023-06-30

83 Using Drosophila to model a variant of unknown significance in the human cardiogenic gene Nkx2.5

Lovato, T. L.; Blotz, B.; Bileckyj, C.; Johnston, C. A.; Cripps, R. M.

10.1101/2023.06.28.546937 — developmental biology — Posted on 2023-06-30

84 Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication

Yang, Z.; Johnson, B. A.; Meliopoulos, V. A.; Ju, X.; Zhang, P.; Hughes, M. P.; Wu, J.; Koreski, K. P.; Chang, T.-C.; Wu, G.; Hixon, J.; Duffner, J.; Wong, K.; Lemieux, R.; Lokugamage, K. G.; Alvardo, R. E.; Crocquet-Valdes, P. A.; Walker, D. H.; Plante, K. S.; Plante, J. A.; Weaver, S. C.; Kim, H. J.; Meyers, R.; Schultz-Cherry, S.; Ding, Q.; Menachery, V. D.; Taylor, J. P.

10.1101/2023.06.29.546885 — cell biology — Posted on 2023-06-30

85 Endothelial Knockdown of the Tumor Suppressor, WWOX, Increases Inflammation in Ventilator-Induced Lung Injury

Zeng, Z.; Abdelwahid, E.; Chen, W.; Ascoli, C.; Pham, T.; Jacobson, J. R.; Dudek, S. M.; Natarajan, V.; Aldaz, C. M.; Machado, R. F.; Singla, S.

10.1101/2023.06.29.547087 — molecular biology — Posted on 2023-06-30

86 Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W.; Goeminne, L. J. E.; Tyshkovskiy, A.; Zhang, S.; Paulo, J. A.; Pierce, K. A.; Choy, A. H.; Clish, C. B.; Gygi, S. P.; Gladyshev, V. N.

10.1101/2023.06.30.546730 — molecular biology — Posted on 2023-06-30

87 A CRISPR-based strategy for targeted sequencing in biodiversity science

Littleford-Colquhoun, B. L.; Kartzinel, T. R.

10.1101/2023.06.30.547247 — molecular biology — Posted on 2023-06-30

88 Discovery of Eremiobacterota with nifH homologs in tundra soil

Pessi, I. S.; Delmont, T.; Zehr, J. P.; Hultman, J.

10.1101/2023.06.30.547195 — microbiology — Posted on 2023-06-30

89 Biodecomposing Spirulina platensis by a de novo designed Bacillus subtilis-based method to develop a medium for the high cell-density cultivation of Escherichia coli in batch mode

Li, X.; Wei, Z.; Ge, J.; Pan, Y.; Chu, X.; Huang, B.; Zhao, J.; Li, Y.; Zhou, Y.

10.1101/2023.06.30.547221 — microbiology — Posted on 2023-06-30

90 Glycine fermentation by C. difficile promotes virulence, spore formation, and is induced by host cathelicidin

Rizvi, A.; Vargas-Cuebas, G.; Edwards, A. N.; DiCandia, M. A.; Carter, Z.; Lee, C. D.; Monteiro, M. P.; McBride, S. M.

10.1101/2023.06.30.547236 — microbiology — Posted on 2023-06-30

91 Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance

Russo, T. A.; Alvarado, C. L.; Davies, C. J.; Drayer, Z. J.; Carlino-MacDonald, U.; Hutson, A.; Luo, T. L.; Martin, M. J.; Corey, B. W.; Moser, K. A.; Rasheed, J. K.; Halpin, A. L.; McGann, P.; Lebreton, F.

10.1101/2023.06.30.547231 — microbiology — Posted on 2023-06-30

92 Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

Orozco, R. C.; Marquardt, K.; Pratumchai, I.; Mowen, K.; Domissy, A.; Teijaro, J. R.; Sherman, L. A.

10.1101/2023.06.28.546768 — immunology — Posted on 2023-06-30

93 Post-exposure intranasal IFNα suppresses replication and neuroinvasion of Venezualen Equine Encephalitis virus within olfactory sensory neurons

Klein, R. S.; Cain, M. D.; Klein, N. R.; Jiang, X.

10.1101/2023.06.30.547169 — immunology — Posted on 2023-06-30

94 Layer-specific microglia activation drives chronic stress-induced synapse loss

Soteros, B. M.; Tillmon, H.; Wollet, M.; General, J.; Chin, H.; Lee, J. B.; Carreno, F. R.; Morilak, D. A.; Kim, J. H.; Sia, G. M.

10.1101/2023.06.28.546889 — neuroscience — Posted on 2023-06-30

95 The functionally plastic rod photoreceptors in the simplex retina of Little skate (Leucoraja erinacea) exhibit a hybrid rod-cone morphology and enhanced synaptic connectivity.

Magana-Hernandez, L.; Wagh, A. S.; Fathi, J. G.; Robles, J. E.; Rubio, B.; Yusuf, Y.; Rose, E. E.; Brown, D. E.; Perry, P. E.; Hamada, E.; Anastassov, I. A.

10.1101/2023.06.28.546621 — neuroscience — Posted on 2023-06-30

96 Validating Dynamic Body Acceleration metrics as a measure of energy expenditure in a Neotropical primate

Rezende, G. C.; Cruz-Neto, A. P.; Borger, L.; Redcliffe, J.; Hambly, C.; Speakman, J. R.; Garbino, G. S. T.; Pissinatti, A.; Moreira, S. B.; Wilson, R. P.; Culot, L.

10.1101/2023.06.29.547103 — zoology — Posted on 2023-06-30

97 In vivo characterization of the optical and hemodynamic properties of the human sternocleidomastoid muscle through ultrasound-guided hybrid near-infrared spectroscopies.

Cortese, L.; Fenandez Esteberena, P.; Zanoletti, M.; Lo Presti, G.; Aranda Velazquez, G.; Ruiz Janer, S.; Buttafava, M.; Renna, M.; Di Sieno, L.; Tosi, A.; Dalla Mora, A.; Dehghani, H.; Wojtkiewicz, S.; de Fraguier, S.; Nguyen-Dinh, A.; Rosinski, B.; Weigel, U. M.; Mesquida, J.; Squarcia, M.; Hanzu, F. A.; Contini, D.; Mora Porta, M.; Durduran, T.

10.1101/2023.06.30.544760 — physiology — Posted on 2023-06-30

98 Meta-analysis of macrophage nanoparticle targeting across blood and solid tumors using an eLDA Topic modeling Machine Learning approach

Brown, C.; Bilynsky, C. S. M.; Gainey, M.; Young, S.; Kitchin, J.; Wayne, E. C.

10.1101/2023.06.29.547096 — bioengineering — Posted on 2023-06-30

99 Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures

Wang, W.; Hariharan, M.; Bartlett, A.; Barragan, C.; Castanon, R.; Rothenberg, V.; Song, H.; Nery, J.; Aldridge, A.; Altshul, J.; Kenworthy, M.; Ding, W.; Liu, H.; Tian, W.; Zhou, J.; Chen, H.; Wei, B.; Gunduz, I. B.; Norell, T.; Broderick, T. J.; McClain, M.; Satterwhite, L.; Burke, T.; Petzold, E.; Shen, X.; Woods, C.; Fowler, V. G.; Ruffin, F.; Panuwet, P.; Barr, D. B.; Beare, J. L.; Smith, A. K.; Spurbeck, R. R.; Vangeti, S.; Ramos, I.; Nudelman, G.; Sealfon, S. C.; Castellino, F.; Walley, A. M.; Evans, T.; Muller, F.; Greenleaf, W. J.; Ecker, J. R.

10.1101/2023.06.29.546792 — genomics — Posted on 2023-06-30

100 Personal transcriptome variation is poorly explained by current genomic deep learning models

Huang, C.; Shuai, R.; Baokar, P.; Chung, R.; Rastogi, R.; Kathail, P.; Ioannidis, N. M.

10.1101/2023.06.30.547100 — genomics — Posted on 2023-06-30

101 Retrovirus-derived RTL9 plays an important role in innate antifungal immunity in the eutherian brain

Ishino, F.; Itoh, J.; Irie, M.; Matsuzawa, A.; Naruse, M.; Suzuki, T.; Hiraoka, Y.; Kaneko-Ishino, T.

10.1101/2023.06.29.547130 — evolutionary biology — Posted on 2023-06-30

102 Deep Divergences Among Cryptic Clades of Epipedobates Poison Frogs

Lopez-Hervas, K.; Santos, J. C.; Ron, S. R.; Betancourth-Cundar, M.; Cannatella, D. C.; Tarvin, R. D.

10.1101/2023.06.29.547117 — evolutionary biology — Posted on 2023-06-30

103 Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

Ernst, A.; Piragyte, I.; MP, A. M.; Le, N. D.; Grandgirard, D.; Leib, S.; Oates, A.; Mercader, N.

10.1101/2023.06.29.547094 — developmental biology — Posted on 2023-06-30

104 SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity

Zhang, F.; Schmidt, F.; Muecksch, F.; Wang, Z.; Gazumyan, A.; Nussenzweig, M. C.; Gaebler, C.; Caskey, M.; Hatziioannou, T.; Bieniasz, P. D.

10.1101/2023.06.30.547241 — microbiology — Posted on 2023-06-30

105 Uncovering the Vital Role of Lipid Droplets in Coronavirus Replication: A Novel Insight Arising from the Biological Activity of 2-Bromopalmitate

Liu, D.; Cruz-Cosme, R.; Wu, Y.; Leibowitz, J. L.; Tang, Q.

10.1101/2023.06.29.547086 — microbiology — Posted on 2023-06-30

106 Reprogramming human B cells with custom heavy chain antibodies

Rogers, G. L.; Huang, C.; Mathur, A.; Huang, X.; Chen, H.-Y.; Stanten, K.; Morales, H.; Chang, C.-H.; Kezirian, E. J.; Cannon, P. M.

10.1101/2023.06.28.546944 — immunology — Posted on 2023-06-30

107 Visualizing alpha-synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo

Straumann, N.; Combes, B. F.; Dean-Ben, X. L.; Steernke, R.; Gerez, J.; Dias, I.; Chen, Z.; Watts, B.; Rostami, I.; Shi, K.; Rominger, A.; Baumann, C. R.; Luo, J.; Noain, D.; Nitsch, R. M.; Okamura, N.; Razansky, D.; Ni, R.

10.1101/2023.06.28.546962 — neuroscience — Posted on 2023-06-30

108 Sex difference in the facilitation of fear learning by prior fear conditioning.

Cole, K.; Parsons, R.

10.1101/2023.06.29.547102 — neuroscience — Posted on 2023-06-30

109 Cellular Substrate of Eligibility Traces

Caya-Bissonnette, L.; Naud, R.; Beïque, J.-C.

10.1101/2023.06.29.547097 — neuroscience — Posted on 2023-06-30

Rahman, S. M.; Hauser, C.; Luebke, A. E.

10.1101/2023.06.28.546965 — neuroscience — Posted on 2023-06-30

111 Personalized connectivity-based network targeting model of TMS for treatment of psychiatric disorders: computational feasibility and reproducibility

Cao, Z.; Xiao, X.; Xie, C.; Wei, L.; Yang, Y.; Zhu, C.

10.1101/2023.06.28.545400 — neuroscience — Posted on 2023-06-30

112 Machine learning reveals the control mechanics of the insect wing hinge

Melis, J. M.; Dickinson, M. H.

10.1101/2023.06.29.547116 — neuroscience — Posted on 2023-06-30

113 Regulation of bacterial stringent response by an evolutionary conserved ribosomal protein L11 methylation

Walukiewicz, H. E.; Farris, Y.; Burnet, M. C.; Feid, S. C.; You, Y.; Christensen, D.; Payne, S. H.; Wolfe, A.; Rao, C.; Nakayasu, E. S.

10.1101/2023.06.29.546327 — systems biology — Posted on 2023-06-30

114 FM3VCF: A Software Library for Accelerating the Loading of Large VCF Files in Genotype Data Analyses

Zuo, Z.; Li, Q.; Li, Z.; Huang, M.; Tang, Y.

10.1101/2023.06.25.546413 — bioinformatics — Posted on 2023-06-30

115 Nanopore Adaptive Sampling Enriches for Antimicrobial Resistance Genes in Microbial Communities

Wrenn, D. C.; Drown, D. M.

10.1101/2023.06.27.546783 — bioinformatics — Posted on 2023-06-30

116 Integrative analysis of microbial 16S gene and shotgun metagenomic sequencing data improves statistical efficiency

Yue, Y.; Read, T.; Fedirko, V.; Satten, G. A.; Hu, Y.

10.1101/2023.06.27.546795 — bioinformatics — Posted on 2023-06-30

117 Contextualising the developability risk of antibodies with lambda light chains using enhanced therapeutic antibody profiling

Raybould, M. I. J.; Turnbull, O. M.; Suter, A.; Guloglu, B.; Deane, C. M.

10.1101/2023.06.28.546839 — bioinformatics — Posted on 2023-06-30

118 Methylphenidate alleviates attentional and sensorimotor dysfunction induced by developmental manganese exposure: Assessment of catecholaminergic receptor involvement

Beaudin, S.; Howard, S. L.; Santiago, N.; Strupp, B. J.; Smith, D. R.

10.1101/2023.06.27.546786 — animal behavior and cognition — Posted on 2023-06-30

119 Well-ST-seq: cost-effective spatial transcriptomics at cellular level and high RNA capture efficiency

Yu, N.; Jin, Z.; Liang, C.; Zhang, J.; Yang, B.

10.1101/2023.06.28.546974 — genomics — Posted on 2023-06-30

120 Pangenome of cultivated beet and crop wild relatives reveals parental relationships of a tetraploid wild beet

Sielemann, K.; Schmidt, N.; Guzik, J.; Kalina, N.; Pucker, B.; Viehöver, P.; Breitenbach, S.; Weisshaar, B.; Heitkam, T.; Holtgräwe, D.

10.1101/2023.06.28.546919 — genomics — Posted on 2023-06-30

121 Comparative analysis of single-cell RNA sequencing methods with and without sample multiplexing

Xie, Y.; Chen, H.; Chellamuthu, V. R.; Lajam, A. b. M.; Albani, S.; Low, A. H. L.; Petretto, E. G.; Behmoaras, J.

10.1101/2023.06.28.546827 — genomics — Posted on 2023-06-30

122 A spatial map of human liver cirrhosis reveals the patho-architecture and gene signatures associated with cell state transitions during liver disease

Hammond, N.; Baker, S. M.; Georgaka, S.; Al-Anbaki, A.; Jokl, E.; Simpson, K.; Athwal, V.; siriwardena, A.; Spiers, H.; Dixon, M.; Bobola, N.; Sharrocks, A.; Hanley, N.; Rattray, M.; Hanley, K. P.

10.1101/2023.06.28.546905 — genomics — Posted on 2023-06-30

123 Estimation of heritabilities and genetic correlations by time slices using predictivity in large genomic models

Misztal, I.

10.1101/2023.06.28.546953 — genetics — Posted on 2023-06-30

124 Unifying optimal offspring size and bacterial aging through resource distribution models

Sakal, T.; Proulx, S. R.

10.1101/2023.06.28.546398 — evolutionary biology — Posted on 2023-06-30

125 Is it selfish to be filamentous in biofilms? Individual-based modeling links microbial growth strategies with morphology using the new and modular iDynoMiCS 2.0

Cockx, B. J. R.; Foster, T.; Clegg, R. J.; Alden, K.; Arya, S.; Stekel, D. J.; Smets, B. F.; Kreft, J.-U.

10.1101/2023.06.27.546816 — ecology — Posted on 2023-06-30

126 The Drosophila cardiogenic transcription factors Myocyte enhancer factor-2 and Tinman contribute to heart lumen enlargement through direct activation of the collagen gene Multiplexin.

Lovato, T.; Ryan, D.; Bileckyj, C.; Johnston, C.; Cripps, R.

10.1101/2023.06.28.546941 — developmental biology — Posted on 2023-06-30

127 Macrophages sense ECM mechanics and growth factor availability through cytoskeletal remodeling to regulate their tissue repair program

Meizlish, M. L.; Kimura, Y.; Pope, S. D.; Matta, R.; Kim, C.; Philip, N.; Meyaard, L.; Gonzalez, A.; Medzhitov, R.

10.1101/2023.06.28.545586 — immunology — Posted on 2023-06-30

128 LRRK2 G2019S promotes the development of colon cancer via modulating intestinal inflammation

Kang, Z.; Wang, Y.; Gao, J. Z.; Sakaguchi, T.; Maretzky, T.; Gurung, P.; Short, S.; Xiong, Y.

10.1101/2023.06.28.546897 — immunology — Posted on 2023-06-30

129 Cortical Origin of Theta Error Signals

Herrera, B.; Sajad, A.; Errington, S. P.; Schall, J. D.; Diaz, J. R.

10.1101/2023.06.27.546752 — neuroscience — Posted on 2023-06-30

130 Oscillatory-Quality of sleep spindles: from properties to function

Blanco-Duque, C.; Bond, S. A.; Krone, L. B.; Dufour, J.-P.; Gillen, E. C. P.; Kahn, M. C.; Purple, R. J.; Bannerman, D. M.; Mann, E. O.; Achermann, P.; Olbrich, E.; Vyazovskiy, V. V.

10.1101/2023.06.28.546981 — neuroscience — Posted on 2023-06-30

131 Fundamental Sex Differences in Cocaine-Induced Plasticity of D1- and D2-MSNs in the Mouse Nucleus Accumbens Shell

Chapp, A. D.; Nwakama, C. A.; Jagtap, P. P.; Phan, C.-M. H.; Thomas, M. J.; Mermelstein, P. G.

10.1101/2023.06.28.546959 — neuroscience — Posted on 2023-06-30

132 Learning better with Dale's Law: A Spectral Perspective

Li, P.; Cornford, J.; Ghosh, A.; Richards, B.

10.1101/2023.06.28.546924 — neuroscience — Posted on 2023-06-30

133 Method to quickly map multifocal Pupillary Response Fields (mPRF) using Frequency Tagging

Lorenceau, J.

10.1101/2023.06.28.546061 — neuroscience — Posted on 2023-06-30

Zheng, L.; Gao, Z.; Doner, S.; Oyao, A.; Forloines, M.; Grilli, M.; Barnes, C. A.; Ekstrom, A. D.

10.1101/2023.06.28.546918 — neuroscience — Posted on 2023-06-30

135 A distributed theta network of error generation and processing in aging

Kolev, V.; Falkenstein, M.; Yordanova, J.

10.1101/2023.06.28.546844 — neuroscience — Posted on 2023-06-30

136 Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

Lin, Y.; Jung, H.; Bulman, C. A.; Ng, J.; Vinck, R.; O'Beirne, C.; Moser, M. S.; Tricoche, N.; Peguero, R.; Li, R. W.; Urban, J. F.; Le Pape, P.; Pagniez, F.; Moretto, M.; Weil, T.; Lustigman, S.; Cariou, K.; Mitreva, M.; Sakanari, J.; Gasser, G.

10.1101/2023.06.28.546819 — pharmacology and toxicology — Posted on 2023-06-30

137 Clinical super-resolution computed tomography of bone microstructure: application in musculoskeletal and dental imaging

Rytky, S. J. O.; Tiulpin, A.; Finnilä, M. A. J.; Karhula, S. S.; Sipola, A.; Kurttila, V.; Valkealahti, M.; Lehenkari, P.; Joukainen, A.; Kröger, H.; Korhonen, R. K.; Saarakkala, S.; Niinimäki, J.

10.1101/2023.06.28.544314 — bioinformatics — Posted on 2023-06-30

138 OrthoPhyl - A turn-key solution for large scale whole genome bacterial phylogenomics

Middlebrook, E.; Katani, R.; Fair, J. M.

10.1101/2023.06.27.546815 — bioinformatics — Posted on 2023-06-30

139 Scalable, accessible, and reproducible reference genome assembly and evaluation in Galaxy

Lariviere, D.; Abueg, L.; Brajuka, N.; Gallardo-Alba, C.; Gruning, B.; Ko, B. J.; Ostrovsky, A.; Palmada-Flores, M.; Pickett, B. D.; Rabbani, K.; Balacco, J. R.; Chaisson, M.; Cheng, H.; Collins, J.; Denisova, A.; Fedrigo, O.; Gallo, G. R.; Giani, A. M.; Gooder, G. M.; Jain, N.; Johnson, C.; Kim, H.; Lee, C.; Marques-Bonet, T.; O'Toole, B.; Rhie, A.; Secomandi, S.; Sozzoni, M.; Tilley, T.; Uliano-Silva, M.; van den Beek, M.; Waterhouse, R. M.; Phillippy, A. M.; Jarvis, E. D.; Schatz, M.; Nekrutenko, A.; Formenti, G.

10.1101/2023.06.28.546576 — bioinformatics — Posted on 2023-06-30

140 A Molecular Communication model for cellular metabolism

Sakkaff, Z.; Freiburger, A.; Catlett, J. L.; Cashman, M.; Immaneni, A.; Buan, N. R.; Cohen, M.; Henry, C.; Pierobon, M.

10.1101/2023.06.28.546976 — bioinformatics — Posted on 2023-06-30

141 Discovering Matrix Adducts for Enhanced Metabolite Profiling with Stable Isotope-Labeled MALDI-MSI

Baquer, G.; Bernus, M.; Semente, L.; van Zeijl, R.; Garcia-Altares, M.; Heijs, B.; Boutureira, O.; Correig, X.; Rafols, P.

10.1101/2023.06.28.546946 — bioinformatics — Posted on 2023-06-30

142 Rescuable sleep and synaptogenesis phenotypes in a Drosophila model of O-GlcNAc transferase intellectual disability.

Czajewski, I.; McDowall, L.; Ferenbach, A. T.; van Aalten, D.

10.1101/2023.06.28.546900 — genetics — Posted on 2023-06-30

143 The irregular fruit green netting: An eggplant domestication trait controlled by the SmGLK2 gene with implications in fruit colour diversification

Arrones, A.; Manrique, S.; Baraja-Fonseca, V.; Plazas, M.; Prohens, J.; Portis, E.; Barchi, L.; Giuliano, G.; Gramazio, P.; Vilanova, S.

10.1101/2023.06.28.546667 — genetics — Posted on 2023-06-30

144 Phylogenomics including new sequence data of phytoplankton-infecting chytrids reveals multiple independent lifestyle transitions across the phylum

Thome, P. C.; Wolinska, J.; Van Den Wyngaert, S.; Rene, A.; Ilicic, D.; Agha, R.; Grossart, H.-P.; Garces, E.; Monaghan, M. T.; Strassert, J. F. H.

10.1101/2023.06.28.546836 — evolutionary biology — Posted on 2023-06-30

145 Disentangling the biotic and abiotic drivers of bird-building collisions in a tropical Asian city using ecological niche modelling.

Tan, D. J.; Freymueller, N.; Teo, K. M.; Symes, W. S.; Lum, S. K.; Rheindt, F. E.

10.1101/2023.06.27.546782 — ecology — Posted on 2023-06-30

146 VARIATIONS IN THE ULTRAVIOLET FLORAL PATTERNS AND POLLINATOR PREFERENCE AMONG SELECTED NON-INVASIVE AND INVASIVE PLANTS OF TAMIL NADU, INDIA

Ravichandran, I. S.; Balasingam, P.; Rajasekaran, M. R.; Ananthapadmanabhan, K.; Muthuvel, M.; Ramalingam, K.; M, V.; Nalluchamy, K.; Soorangkattan, S.; MR, A.; Sivagnanam, C.

10.1101/2023.06.27.546802 — ecology — Posted on 2023-06-30

147 Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and human to ethanol-induced jaw malformations

Klem, J. R.; Schwantes-An, T.-H.; Abreu, M.; Suttie, M.; Gray, R.; Vo, H.; Conley, G.; Foroud, T. M.; Wetherill, L.; CIFASD, ; lovely, c. B.

10.1101/2023.06.28.546932 — developmental biology — Posted on 2023-06-30

148 Characterization of CAR T Cells Manufactured using Genetically Engineered Artificial Antigen Presenting Cells

Sayadmanesh, A.; Azadbakht, M.; Yari, K.; Abedelahi, A.; Shafaei, H.; Shanehbandi, D.; Baradaran, B.; Basiri, M.

10.1101/2023.06.28.546908 — immunology — Posted on 2023-06-30

149 Age-dependent decrease in inhibitory drive on the excitatory superficial spinal dorsal horn neurons

Rayi, P. R.; Lev, S. M.; Binshtok, A. M.

10.1101/2023.06.28.546829 — neuroscience — Posted on 2023-06-30

150 Neurophysiological correlates of Somatosensory tinnitus modulation

Schmitt, A.; Kim, C.; Rampp, S.; Buchfelder, M.; Mueller-Voggel, N.

10.1101/2023.06.28.546718 — neuroscience — Posted on 2023-06-30

151 Visual shape discrimination in goldfish, modelled with the neural circuitry of optic tectum and torus longitudinalis.

NORTHMORE, D.

10.1101/2023.06.28.546845 — neuroscience — Posted on 2023-06-30

152 The influence of movement speed on reward-based motor learning

van Mastrigt, N. M.; van der Kooij, K.; Smeets, J.

10.1101/2023.06.28.546754 — neuroscience — Posted on 2023-06-30

153 Multimodal layer modeling reveals in-vivo pathology in ALS

Northall, A.; Doehler, J.; Weber, M.; Tellez, I.; Petri, S.; Prudlo, J.; Vielhaber, S.; Schreiber, S.; Kuehn, E.

10.1101/2023.06.28.546951 — neuroscience — Posted on 2023-06-30

154 Decoding object categories from EEG during free viewing reveals early information evolution compared to passive viewing

Auerbach-Asch, C. R.; Vishne, G.; Wertheimer, O.; Deouell, L. Y.

10.1101/2023.06.28.546397 — neuroscience — Posted on 2023-06-30

155 Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect outcome

Haley, M. J.; Bere, L.; Minshull, J.; Georgaka, S.; Garcia-Martin, N.; Howell, G.; Coope, D. J.; Roncaroli, F.; King, A.; Wedge, D.; Allan, S.; Pathmanaban, O. N.; Brough, D.; Couper, K.

10.1101/2023.06.30.547190 — cancer biology — Posted on 2023-06-30

156 PSite: inference of read-specific P-site offsets for ribosomal footprints

Chang, Y.; Lei, T.; Zhang, H.

10.1101/2023.06.27.546788 — bioinformatics — Posted on 2023-06-30

157 Reducing PSY activity fine tunes threshold levels of a cis-carotene-derived signal that regulates the PIF3/HY5 module and plastid biogenesis

Hou, X.; Alagoz, Y.; Welsch, R.; Mortimer, M.; Pogson, B. J.; Cazzonelli, C. I.

10.1101/2023.06.29.546996 — plant biology — Posted on 2023-06-30

158 Contextualising samples: Supporting reference genomes for European biodiversity through sample and associated metadata collection

Boehne, A.; Fernandez, R.; Leonard, J. A.; McCartney, A. M.; McTaggart, S.; Melo-Ferreira, J.; Monteiro, R.; Oomen, R. A.; Vinnere Pettersson, O.; Struck, T. H.

10.1101/2023.06.28.546652 — genomics — Posted on 2023-06-30

159 Structure and replication cycle of a virus infecting climate-modulating alga Emiliania huxleyi

Homola, M.; Buttner, C. R.; Fuzik, T.; Krepelka, P.; Holbova, R.; Novacek, J.; Chaillet, M.; Forster, F.; Wilson, W. H.; Schroeder, D. C.; Plevka, P.

10.1101/2023.06.30.547180 — molecular biology — Posted on 2023-06-30

160 The evolutionary history of hepaciviruses

Li, Y.; Ghafari, M.; Holbrook, A. J.; Boonen, I.; Amor, N. M. S.; Catalano, S.; Webster, J. P.; Li, Y.; Li, H.; Vergote, V.; Maes, P.; Chong, Y. L.; Laudisoit, A.; Baelo, P.; Ngoy, S.; Mbalitini, S. G.; Gembu, G.-C.; Akawa, P. M.; Gouy de Bellocq, J.; Leirs, H.; Verheyen, E.; Pybus, O. G.; Katzourakis, A.; Alagaili, A.; Gryseels, S.; Li, Y.; Suchard, M. A.; Bletsa, M.; Lemey, P.

10.1101/2023.06.30.547218 — microbiology — Posted on 2023-06-30

161 Metabolomic approaches highlight two mechanisms of accelerated grain filling in Mediterranean oat (Avena sativa L.) cultivars during drought.

Girija, A.; CANALES CASTILLA, F. J.; Haddadi, B. S.; Dye, R.; Corke, F.; Han, J.; Brooke, J.; Williams, K.; Beckmann, M.; Prats, E.; Doonan, J.; Mur, L. A.

10.1101/2023.06.28.546978 — plant biology — Posted on 2023-06-30

162 Genome-wide analysis of promoter contacts identifies novel regulators of late-stage adipogenesis

Sandovici, I.; Mifsud, B.; Emery, A.; Gulati, P.; Kentistou, K. A.; Banu, A.; Hardwick, B. S.; Campbell, N.; Crooks, A. T.; Fernandez-Twinn, D. S.; Mennitti, L. V.; Srour, L.; Awad, S.; Chiarugi, D.; Hamilton, R. H.; Wingett, S. W.; Fraser, P.; Ong, K. K.; Shoenfelder, S.; Mohammad, F.; O'Rahilly, S.; Perry, J. R. B.; Venkitaraman, A. R.; E. Ozanne, S.; Constancia, M.

10.1101/2023.06.27.546683 — genetics — Posted on 2023-06-30

163 Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza

Lee, C. K.; Oliveira, L. V. N.; Akalin, A.; Specht, C.; Lourenco, D.; Gomez, C. L.; Ramirez-Ortiz, Z. G.; Wang, J. P.; Levitz, S. M.

10.1101/2023.06.27.546808 — immunology — Posted on 2023-06-30

164 NeuroMabSeq: high volume acquisition, processing, and curation of hybridoma sequences and their use in generating recombinant monoclonal antibodies and scFvs for neuroscience research

Mitchell, K. G.; Gong, B.; Hunter, S. S.; Burkart-Waco, D.; Gavira-ONeill, C. E.; Templeton, K. M.; Goethel, M. E.; Bzymek, M.; MacNiven, L. M.; Murray, K. D.; Settles, M. L.; Froenicke, L.; Trimmer, J. S.

10.1101/2023.06.28.546392 — neuroscience — Posted on 2023-06-30

165 Multifactorial analysis of terminator performance on heterologous gene expression in Physcomitrella

Niederau, P. A.; Egle, P.; Willig, S.; Parsons, J.; Hoernstein, S. N. W.; Decker, E. L.; Reski, R.

10.1101/2023.06.30.547182 — plant biology — Posted on 2023-06-30

166 Characterization of a uranium-tolerant green microalga of the genus Coelastrella with high potential for the remediation of metal-polluted waters

Beaulier, C.; Dannay, M.; Devime, F.; Baggio, C.; El Sakkout, N.; Raillon, C.; Courson, O.; Bourguignon, J.; ALBAN, C.; Ravanel, S.

10.1101/2023.06.29.546994 — plant biology — Posted on 2023-06-30

167 High genomic plasticity and unique features of Xanthomonas translucens pv. graminis revealed through comparative analysis of complete genome sequences

Goettelmann, F.; Koebnik, R.; Roman-Reyna, V.; Studer, B.; Koelliker, R.

10.1101/2023.06.29.547023 — plant biology — Posted on 2023-06-30

168 eIF3e and eIF3d control expression of riboproteins and key components of the MAPK signaling pathway.

Valasek, L. S.; Herrmannova, A.; Jelinek, J.; Pospisilova, K.; Kerenyi, F.; Vomastek, T.; Brabek, J.; Mohammad, M. P.; Wagner, S.

10.1101/2023.06.29.547003 — molecular biology — Posted on 2023-06-30

169 SPPUSM: An MS/MS spectra merging strategy for improved low-input and single-cell proteome identification

Chen, Y.; Du, Z.; Zhao, H.; Fang, W.; Liu, T.; Zhang, Y.; Zhang, W.; Qin, W.

10.1101/2023.06.29.547039 — molecular biology — Posted on 2023-06-30

170 Profiling of Zea mays L. proteome at early stages of compatible interactions with Meloidogyne arenaria indicates changes in signaling, oxidative stress responses, and S-adenosylmethionine biosynthesis

Przybylska, A.; Wrzesinska-Krupa, B.; Obrepalska-Steplowska, A.

10.1101/2023.06.28.546826 — plant biology — Posted on 2023-06-30

171 Quantitative assessment of single-cell RNA-seq clustering with CONCORDEX

Jackson, K. C.; Booeshaghi, A. S.; Galvez-Merchan, A.; Moses, L.; Chari, T.; Pachter, L.

10.1101/2023.06.28.546949 — bioinformatics — Posted on 2023-06-30

172 Assessment of ethanol and nicotine interactions using a reinforcer demand modeling with grouped and individual levels of analyses in a long-access self-administration model using male rats.

Robison, C. L.; Cova, N.; Madore, V.; Allen, T.; Barrett, S.; Charntikov, S.

10.1101/2022.10.17.512519 — animal behavior and cognition — Posted on 2023-06-30

173 Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution

Nadalin, F.; Marzi, M. J.; Piscazzi, M. P.; Fuentes, P.; Procaccia, S.; Climent, M.; Bonetti, P.; Rubolino, C.; Giuliani, B.; Papatheodorou, I.; Marioni, J. C.; Nicassio, F.

10.1101/2023.06.28.546923 — genomics — Posted on 2023-06-30

174 Sex peptide receptor is not required for refractoriness to remating or induction of egg laying in Aedes aegypti

Amaro, I. A.; Wohl, M. P.; Pitcher, S.; Alfonso-Parra, C.; Avila, F. W.; Paige, A. S.; Helinski, M.; Duvall, L. B.; Harrington, L. C.; Wolfner, M. F.; McMeniman, C. J.

10.1101/2023.06.28.546954 — genetics — Posted on 2023-06-30

175 Crop modeling suggests limited transpiration would increase yield of sorghum across drought-prone regions of the United States

Raymundo, R.; Mclean, G.; Sexton-Bowser, S.; Morris, G. P.

10.1101/2023.06.27.546776 — genetics — Posted on 2023-06-30

176 The extracellular matrix differentially directs myoblast motility in distinct forms of muscular dystrophy

Long, A. M.; Kwon, J.; Reiser, N. L.; Vaught, L. A.; O'Brien, J. G.; Page, P. G. T.; Lee, G.; Hadhazy, M.; Reynolds, J. C.; Crosbie, R. H.; Demonbreun, A. R.; McNally, E. M.

10.1101/2022.10.31.514525 — molecular biology — Posted on 2023-06-30

177 Mycobiome analyses of critically ill COVID-19 patients

Weaver, D.; Gago, S.; Bassetti, M.; Giacobbe, D. R.; Prattes, J.; Hoenigl, M.; Reizine, F.; Guegan, H.; Gangneux, J.-P.; Bromley, M. J.; Bowyer, P.

10.1101/2023.06.13.543274 — microbiology — Posted on 2023-06-30

178 CHIR99021 causes inactivation of Tyrosine Hydroxylase and depletion of dopamine in rat brain striatum

Hamdon, S.; Fernandez-Gonzalez, P.; Omar, M. Y.; Gonzalez-Sepulveda, M.; Ortiz, J.; Gil, C.

10.1101/2023.05.15.540370 — neuroscience — Posted on 2023-06-30

179 Application of a 1H Brain MRS Benchmark Dataset to Deep Learning for Out-of-Voxel Artifacts

Gudmundson, A. T.; Davies-Jenkins, C. W.; Ozdemir, I.; Murali-Manohar, S.; Zollner, H. J.; Song, Y.; Hupfeld, K. E.; Schnitzler, A.; Oeltzschner, G.; Stark, C. E. L.; Edden, R. A. E.

10.1101/2023.05.08.539813 — neuroscience — Posted on 2023-06-30

180 Different rules for binocular combination of luminance flicker in cortical and subcortical pathways

Segala, F. G.; Bruno, A.; Martin, J. T.; Aung, M. T.; Wade, A. R.; Baker, D. H.

10.1101/2023.01.11.523568 — neuroscience — Posted on 2023-06-30

181 Post-Transplant Administration of G-CSF Impedes Engraftment of Gene Edited Human Hematopoietic Stem Cells by Exacerbating the p53-Mediated DNA Damage Response

Araki, D.; Chen, V.; Redekar, N.; Salisbury-Ruf, C.; Luo, Y.; Liu, P.; Li, Y.; Smith, R.; Dagur, P.; Combs, C.; Larochelle, A.

10.1101/2023.06.29.547089 — cell biology — Posted on 2023-06-30

182 Matrix stiffening promotes perinuclear clustering of mitochondria

Daga, P.; Thurakkal, B.; Rawal, S.; Das, T.

10.1101/2023.06.29.547150 — cell biology — Posted on 2023-06-30

183 Mechanistic constraints on the trade-off between photosynthesis and respiration in response to warming

Leles, S. G.; Levine, N. M.

10.1101/2023.06.29.546917 — cell biology — Posted on 2023-06-30

184 Mechanical coupling coordinates microtubule growth

Leeds, B. K.; Kostello, K. F.; Liu, Y. Y.; Biggins, S.; Asbury, C. L.

10.1101/2023.06.29.547092 — cell biology — Posted on 2023-06-30

185 Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Kaya, H. E. K.; Ward, M. A.; Vangala, J. R.; Byers, H. A.; Diaz, A.; Kaushik, S.; Cuervo, A. M.; Radhakrishnan, S. K.

10.1101/2023.06.29.547114 — cell biology — Posted on 2023-06-30

186 Single cell-resolution in situ sequencing elucidates spatial dynamics of multiple sclerosis lesion and disease evolution

Langseth, C. M.; Kukanja, P.; Rodriguez-Kirby, L. A. R.; Agirre, E.; Raman, A.; Yokota, C.; Avenel, C.; Tiklova, K.; Guerreiro-Cacais, A. O.; Olsson, T.; Hilscher, M. M.; Nilsson, M.; Castelo-Branco, G.

10.1101/2023.06.29.547074 — cell biology — Posted on 2023-06-30

187 The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix

O'Brien, J. G.; Willis, A. B.; Long, A. M.; Kwon, J.; Lee, G.; Li, F.; Page, P. G.; Vo, A. H.; Hadhazy, M.; Crosbie, R. H.; Demonbreun, A. R.; McNally, E. M.

10.1101/2023.06.29.547098 — cell biology — Posted on 2023-06-30

188 Identification of cross-reacting IgG hotspots to prevent immune evasion of SARS-CoV-2 variants

Harhala, M.; Gembara, K.; Baniecki, K.; Pikies, A.; Nahorecki, A.; Jedruchniewicz, N.; Kazmierczak, Z.; Rybicka, I.; Klimek, T.; Witkiewicz, W.; Barczyk, K.; Kłak, M.; Dabrowska, K.

10.1101/2023.06.27.546805 — immunology — Posted on 2023-06-30

189 gARID-associated chromatin remodeling events are essential for gametocyte development in Plasmodium

Nishi, T.; Kaneko, I.; Iwanaga, S.; Yuda, M.

10.1101/2023.06.29.546992 — molecular biology — Posted on 2023-06-30

190 Neural mechanisms of serial dependence in time perception: The impact of prior task and memory processing

Cheng, S.; Chen, S.; Glasauer, S.; Keeser, D.; Shi, Z.

10.1101/2023.05.07.538104 — neuroscience — Posted on 2023-06-30

191 Bipartite left-right sided endocrine system: processing of contralateral effects of brain injury

Watanabe, H.; Kobikov, Y.; Nosova, O.; Sarkisyan, D.; Galatenko, V.; Carvalho, L.; Maia, G. H.; Lukoyanov, N.; Lavrov, I.; Hallberg, M.; Schouenborg, J.; Zhang, M.; Bakalkin, G.

10.1101/2023.06.28.546857 — neuroscience — Posted on 2023-06-30

192 System Neglect and the Neurocomputational Substrates for Over- and Underreactions to Change

Wang, M.-C.; Wu, G.; Wu, S.-W.

10.1101/2023.05.30.542806 — neuroscience — Posted on 2023-06-30

193 SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis

Theard, P. L.; Linke, A. J.; Sealover, N. E.; Daley, B. R.; Yang, J.; Cox, K.; Kortum, R. L.

10.1101/2023.01.20.524989 — cancer biology — Posted on 2023-06-29

194 A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis

Luo, G.; Kumar, H.; Alridge, K.; Rieger, S.; Jiang, E.; Chan, E. R.; Soliman, A.; Mahdi, H.; Letterio, J. J.

10.1101/2023.04.20.537691 — cancer biology — Posted on 2023-06-30

195 An adversarial collaboration to critically evaluate theories of consciousness

Cogitate Consortium, ; Ferrante, O.; Gorska-Klimowska, U.; Henin, S.; Hirschhorn, R.; Khalaf, A.; Lepauvre, A.; Liu, L.; Richter, D.; Vidal, Y.; Bonacchi, N.; Brown, T.; Sripad, P.; Armendariz, M.; Bendtz, K.; Ghafari, T.; Hetenyi, D.; Jeschke, J.; Kozma, C.; Mazumder, D. R.; Montenegro, S.; Seedat, A.; Sharafeldin, A.; Yang, S.; Baillet, S.; Chalmers, D. J.; Cichy, R. M.; Fallon, F.; Panagiotaropoulos, T. I.; Blumenfeld, H.; Devore, S.; Jensen, O.; Kreiman, G.; de Lange, F. P.; Luo, H.; Boly, M.; Dehaene, S.; Koch, C.; Tononi, G.; Pitts, M.; Mudrik, L.; Melloni, L.

10.1101/2023.06.23.546249 — neuroscience — Posted on 2023-06-30

196 Population encoding of stimulus features along the visual hierarchy

Dyballa, L.; Rudzite, A. M.; Hoseini, M. S.; Thapa, M.; Stryker, M. P.; Field, G. D.; Zucker, S. W.

10.1101/2023.06.27.545450 — neuroscience — Posted on 2023-06-30

197 Kir2.1 modulation in macrophages sensitises dorsal root ganglion neurons through TNF secretion after nerve injury

Konnova, E. A.; Deftu, A.-F.; Chu Sin Chung, P.; Kirschmann, G.; Decosterd, I.; Suter, M. R.

10.1101/2023.06.21.545843 — neuroscience — Posted on 2023-06-30

198 Action does not enhance but attenuates predicted touch

Job, X.; Kilteni, K.

10.1101/2023.04.03.535383 — neuroscience — Posted on 2023-06-30

199 High School Science Fair: School Location Trends in Student Participation and Experience

Grinnell, F.; Dalley, S.; Reisch, J.

10.1101/2023.02.01.526679 — scientific communication and education — Posted on 2023-06-30

200 Role of 14-3-3 proteins in human cardiac sodium channel Nav1.5 regulation

Iamshanova, O.; Hämmerli, A.-F.; Ramaye, E.; Seljmani, A.; Ross-Kaschitza, D.; Schärz, N.; Essers, M.; Guichard, S.; Rougier, J.-S.; Abriel, H.

10.1101/2022.10.26.513875 — biophysics — Posted on 2023-06-30

201 Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock

Tariq, D.; Maurici, N.; Bartholomai, B.; Chandrasekaran, S.; Dunlap, J. C.; Bah, A.; CRANE, B. R.

10.1101/2022.11.03.515097 — biochemistry — Posted on 2023-06-30

202 Genomic refugium of pre-domestication lineages in the Bronze Age Carpathian Basin

Dicso, Z.; Szabo, G.; Bozi, R.; Borbely, N.; Heltai, B.; Kulcsar, G.; Mende, B. G.; Kiss, V.; Szecsenyi-Nagy, A.; Gerber, D.

10.1101/2023.06.29.547029 — evolutionary biology — Posted on 2023-06-30

203 A partial Drp1 knockout improves autophagy flux independent of mitochondrial function

Fan, R.; Sportelli, C.; Lai, Y.; Salehe, S.; Pinnell, J.; Richardson, J. R.; Luo, S.; Tieu, K.

10.1101/2023.06.29.547095 — cell biology — Posted on 2023-06-30

204 Discovery of novel DNA cytosine deaminase activities enables a nondestructive single-enzyme methylation sequencing method for base resolution high-coverage methylome mapping of cell-free and ultra-low input DNA

Vaisvila, R.; Johnson, S. R.; Yan, B.; Dai, N.; Bourkia, B. M.; Correa, I. R.; Yigit, E.; Sun, Z.

10.1101/2023.06.29.547047 — molecular biology — Posted on 2023-06-30

205 Valorization of Organic Fraction of Municipal Solid Waste Through Production of Volatile Fatty Acids (VFAs) and Biogas

Borhany, H.

10.1101/2023.06.21.545938 — microbiology — Posted on 2023-06-30

206 Dynamic saccade context triggers more stable object-location binding

Lu, Z.; Golomb, J. D.

10.1101/2023.04.26.538469 — neuroscience — Posted on 2023-06-30

207 Encoding and context-dependent control of reward consumption within the central nucleus of the amygdala

Fraser, K. M.; Kim, T. H.; Castro, M.; Drieu, C.; Padovan-Hernandez, Y.; Chen, B. J.; Pat, F.; Ottenheimer, D. J.; Janak, P. H.

10.1101/2023.06.28.546936 — neuroscience — Posted on 2023-06-30

208 Predicting Executive Functioning from Brain Networks: Modality Specificity and Age Effects

Heckner, M. K.; Cieslik, E. C.; Paas Oliveros, L. K.; Eickhoff, S. B.; Patil, K. R.; Langner, R.

10.1101/2023.06.29.547036 — neuroscience — Posted on 2023-06-30

209 Developmental molecular controls over arealization of descending cortical motor pathways

Abe, P.; Lavalley, A.; Morassut, I.; Klingler, E.; Santinha, A. J.; Platt, R. J.; Jabaudon, D.

10.1101/2023.06.29.546438 — neuroscience — Posted on 2023-06-30

210 Neuronal wiring diagram of an adult brain

Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. E.; Lin, A.; Costa, M.; Eichler, K.; Yin, Y.; Silversmith, W.; Schneider-Mizell, C.; Jordan, C. S.; Brittain, D.; Halageri, A.; Kuehner, K.; Ogedengbe, O.; Morey, R.; Gager, J.; Kruk, K.; Perlman, E.; Yang, R.; Deutsch, D.; Bland, D.; Sorek, M.; Lu, R.; Macrina, T.; Lee, K.; Bae, J. A.; Mu, S.; Nehoran, B.; Mitchell, E.; Popovych, S.; Wu, J.; Jia, Z.; Castro, M.; Kemnitz, N.; Ih, D.; Bates, A. S.; Eckstein, N.; Funke, J.; Collman, F.; Bock, D. D.; Jefferis, G. S. X. E.; Seung, H. S.; Murthy, M.; the FlyWire Co

10.1101/2023.06.27.546656 — neuroscience — Posted on 2023-06-30

211 Genetic influences on motor learning and superperformance mutants revealed by random mutational survey of mouse locomotion

Jakkamsetti, V.; Ma, Q.; Angulo, G.; Scudder, W.; Beutler, B.; Pascual, J. M.

10.1101/2023.06.28.546756 — neuroscience — Posted on 2023-06-30

212 lmeEEG: Mass linear mixed-effects modeling of EEG data with crossed random effects

Visalli, A.; Montefinese, M.; Viviani, G.; Finos, L.; Vallesi, A.; Ambrosini, E.

10.1101/2023.01.18.524560 — neuroscience — Posted on 2023-06-30

213 Emergence of Supercoiling-Mediated Regulatory Networks through Bacterial Chromosome Organization

Grohens, T.; Meyer, S.; Beslon, G.

10.1101/2022.09.23.509185 — systems biology — Posted on 2023-06-29

214 A Platform for Controlled Template-Independent Enzymatic Synthesis of RNA Oligonucleotides and Therapeutics

Wiegand, D. J.; Rittichier, J.; Meyer, E.; Lee, H.; Conway, N. J.; Ahlstedt, D.; Yurtsever, Z.; Rainone, D.; Kuru, E.; Church, G.

10.1101/2023.06.29.547106 — synthetic biology — Posted on 2023-06-29

215 Vegetative Phase Change Causes Age-Dependent Changes in Phenotypic Plasticity

Lawrence-Paul, E. H.; Poethig, R. S.; Lasky, J.

10.1101/2021.11.02.467012 — plant biology — Posted on 2023-06-30

216 Fungal small RNAs ride in extracellular vesicles to enter plant cells through clathrin-mediated endocytosis

He, B.; Wang, H.; Liu, G.; Chen, A.; Cai, Q.; Jin, H.

10.1101/2023.06.15.545159 — plant biology — Posted on 2023-06-30

217 OpenLabCluster: Active Learning Based Clustering and Classification of Animal Behaviors in Videos Based on Automatically Extracted Kinematic Body Keypoints

Li, J.; Keselman, M. L.; Shlizerman, E.

10.1101/2022.10.10.511660 — animal behavior and cognition — Posted on 2023-06-29

218 How often are male mosquitoes attracted to humans?

Paris, V.; Hardy, C.; Hoffmann, A. A.; Ross, P. A.

10.1101/2023.03.08.531798 — animal behavior and cognition — Posted on 2023-06-30

219 Interdisciplinary analyses of Bronze Age communities from Western Hungary reveal complex population histories

Gerber, D.; Szeifert, B.; Szekely, O.; Egyed, B.; Gyuris, B.; Giblin, J. I.; Horvath, A.; Kohler, K.; Kulcsar, G.; Kustar, A.; Major, I.; Molnar, M.; Palcsu, L.; Szeverenyi, V.; Fabian, S.; Mende, B. G.; Bondar, M.; Ari, E.; Kiss, V.; Szecsenyi-Nagy, A.

10.1101/2022.02.03.478968 — genomics — Posted on 2023-06-29

220 Cell type-specific and disease-associated eQTL in the human lung

Natri, H. M.; Del Azodi, C. B.; Peter, L.; Taylor, C. J.; Chugh, S.; Kendle, R.; Chung, M.-i.; Flaherty, D. K.; Matlock, B. K.; Calvi, C. L.; Blackwell, T. S.; Ware, L. B.; Bacchetta, M.; Walia, R.; Shaver, C. M.; Kropski, J. A.; McCarthy, D. J.; Banovich, N. E.

10.1101/2023.03.17.533161 — genomics — Posted on 2023-06-29

221 Comprehensive Assessment of Eleven de novo HiFi Assemblers on Complex Eukaryotic Genomes and Metagenomes

Yu, W.; Luo, H.; Yang, J.; Zhang, S.; Jiang, H.; Zhao, X.; Hui, X.; Sun, D.; Li, L.; Wei, X.-q.; Lonardi, S.; Pan, W.

10.1101/2023.06.29.546998 — genomics — Posted on 2023-06-29

222 Fast and flexible joint fine-mapping of multiple traits via the Sum of Single Effects model

Zou, Y.; Carbonetto, P.; Xie, D.; Wang, G.; Stephens, M.

10.1101/2023.04.14.536893 — genomics — Posted on 2023-06-30

223 Haplotype-based analysis distinguishes maternal-fetal genetic contribution to pregnancy-related outcomes

Srivastava, A. K.; Juodakis, J.; Sole-Navais, P.; Chen, J.; Bacelis, J.; Teramo, K.; Hallman, M.; Njolstad, P. R.; Evans, D. M.; Jacobsson, B.; Muglia, L. J.; Zhang, G.

10.1101/2020.05.12.079863 — genetics — Posted on 2023-06-30

224 Relationship between prokaryotic GC content and environmental salinity

Hu, E.-Z.; Sun, S.; Niu, D.-K.

10.1101/2023.05.07.539728 — evolutionary biology — Posted on 2023-06-29

225 Epistasis Arises from Shifting the Rate-Limiting Step during Enzyme Evolution

Frohlich, C.; Bunzel, H. A.; Buda, K.; Mulholland, A. J.; van der Kamp, M. W.; Johnsen, P. J.; Leiros, H.-K. S.; Tokuriki, N.

10.1101/2023.06.29.547057 — evolutionary biology — Posted on 2023-06-29

226 Structural asymmetry in biotic interactions as a tool to understand and predict ecological persistence

Allen-Perkins, A.; Garcia-Callejas, D.; Bartomeus, I.; Godoy, O.

10.1101/2023.01.25.525558 — ecology — Posted on 2023-06-29

227 Rapid species discovery and identification with real-time barcoding facilitated by ONTbarcoder 2.0 and Oxford Nanopore R10.4

Srivathsan, A.; Feng, V.; Ramos, D.; Meier, R.

10.1101/2023.06.26.546538 — ecology — Posted on 2023-06-29

228 Evaluation of In2Care mosquito stations for suppression of the Australian backyard mosquito, Aedes notoscriptus

Paris, V.; Bell, N.; Schmidt, T. L.; Endersby-Harshman, N. M.; Hoffmann, A. A.

10.1101/2023.03.20.533559 — ecology — Posted on 2023-06-29

229 Relationship between the colors of the rivers in the Amazon and the incidence of malaria

Fonseca, F.; Martinez, J.-M.; Balieiro, A.; Orellana, J.; Filizola, N.

10.1101/2023.06.29.547004 — ecology — Posted on 2023-06-29

230 The catalytic-independent function of LSD1 modulates the epigenetic landscape of mouse embryonic stem cells

Malla, S.; Kumari, K.; Martinez-Gamero, C.; Garcia-Prieto, C. A.; Stransky, S.; Caroli, J.; Alvarez-Errico, D.; Saiki, P. A.; Lai, W.; Lyu, C.; Gilthorpe, J. D.; Wang, H.; Sidoli, S.; Mattevi, A.; Mateus, A.; Esteller, M.; Roman, A.; Aguilo, F.

10.1101/2023.06.29.547010 — molecular biology — Posted on 2023-06-29

231 C-terminal amides mark proteins for degradation via SCF/FBXO31

Muhar, M.; Farnung, J.; Hofmann, R.; Cernakova, M.; Sidiropoulos, N. D.; Bode, J. W.; Corn, J. E.

10.1101/2023.06.29.547030 — cell biology — Posted on 2023-06-30

232 Investigating Metabolic Trends in the Oral Cavity to Identify Novel Metabolites

Okiye, M. E. K.; Velez, M.; Kinney, J.; Van Sugai, J.; Giannobile, W.; Tripathi, A.; Sherman, D. H.

10.1101/2023.06.26.546600 — microbiology — Posted on 2023-06-29

233 Murine Gammaherpesvirus 68 Efficiently Infects Myeloid Cells Resulting In An Atypical, Restricted Form Of Infection

Vragel, G.; Gomez, B. D.; Kostelecky, R. E.; Noell, K. S.; Tseng, A.; Cohen, S.; Dalwadi, M.; Medina, E. M.; Nail, E. A.; Goodspeed, A.; Clambey, E. T.; van Dyk, L. F.

10.1101/2023.06.21.545948 — microbiology — Posted on 2023-06-29

234 A cytoplasmic chemoreceptor and Reactive Oxygen Species mediate bacterial chemotaxis to copper

Louis, G.; Cherry, P.; Michaux, C.; Rahuel-Clermont, S.; Dieu, M.; Tilquin, F.; Maertens, L.; Van Houdt, R.; Renard, P.; Perpete, E.; Matroule, J.-Y.

10.1101/2022.06.29.497744 — microbiology — Posted on 2023-06-29

235 An ancient ecospecies of Helicobacter pylori found in Indigenous populations and animal adapted lineages.

Tourrette, E.; Torres, R. C.; Svensson, S. L.; Matsumoto, T.; Fauzia, K. A.; Alfaray, R. I.; Vilaichone, R.-K.; Tuan, V. P.; HelicobacterGenomicsConsortium, ; Wang, D.; Olsson, L.; Yadegar, A.; Zhou, Z.; Yamaoka, Y.; Thorell, K.; Falush, D.

10.1101/2023.04.28.538659 — microbiology — Posted on 2023-06-29

236 Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus

Pruitt, E. L.; Zhang, R.; Ross, D. H.; Ashford, N. K.; Chen, X.; Alonzo, F.; Bush, M. F.; Werth, B. J.; Xu, L.

10.1101/2023.06.29.547085 — microbiology — Posted on 2023-06-29

237 Syndiniales parasites drive species networks and are a biomarker for carbon export in the oligotrophic ocean

Anderson, S. R.; Blanco-Bercial, L.; Carlson, C. A.; Harvey, E. L.

10.1101/2023.06.29.547083 — microbiology — Posted on 2023-06-29

238 The Novel Silver-Containing Antimicrobial Potentiates Aminoglycoside Activity Against Pseudomonas aeruginosa.

Donkor, G. Y.; Anderson, G. M.; Stadler, M.; Tawiah, P. O.; Orellano, C. D.; Edwards, K. A.; Dahl, J.-U.

10.1101/2023.03.15.532855 — microbiology — Posted on 2023-06-30

239 Vibrio cholerae Arrests Intestinal Epithelial Proliferation through T6SS-dependent Activation of the Bone Morphogenetic Protein Pathway.

Xu, X.; Foley, E.

10.1101/2023.06.29.547108 — immunology — Posted on 2023-06-29

240 Inflammatory macrophages prevent colonic goblet and enteroendocrine cell differentiation through Notch signaling

Atanga, R.; Romero, A. S.; Hernandez, A. J.; Peralta-Herrera, E.; Merkley, S.; In, J. G.; Castillo, E. F.

10.1101/2023.06.29.547119 — immunology — Posted on 2023-06-29

241 Graded sensitivity to structure and meaning throughout the human language network

Shain, C.; Kean, H.; Casto, C.; Lipkin, B.; Affourtit, J.; Siegelman, M.; Mollica, F.; Fedorenko, E.

10.1101/2021.11.12.467812 — neuroscience — Posted on 2023-06-29

242 Nausea-induced suppression of feeding is mediated by central amygdala Dlk1 expressing neurons

Ding, W.; Weltzien, H.; Peters, C.; Klein, R.

10.1101/2023.06.29.547043 — neuroscience — Posted on 2023-06-29

243 Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer's disease

D'Oliveira Albanus, R.; Finan, G. M.; Brase, L.; Chen, S.; Guo, Q.; Kannan, A.; Acquarone, M.; You, S.-F.; Novotny, B. C.; Ribeiro Pereira, P. M.; Morris, J. C.; Holtzman, D. M.; McDade, E.; Farlow, M.; Chhatwal, J. P.; Dominantly Inherited Alzheimer Network (DIAN), ; Mace, E. E.; Benitez, B. A.; Piccio, L.; Sutherland, G. T.; Ma, Q.; Fu, H.; Karch, C. M.; Harari, O.; Kim, T.-W.

10.1101/2022.11.11.516215 — neuroscience — Posted on 2023-06-29

244 Prediction error drives associative olfactory learning and conditioned behavior in a spiking model of Drosophila larva

Juergensen, A.-M.; Sakagiannis, P.; Schleyer, M.; Gerber, B.; Nawrot, M. P.

10.1101/2022.12.21.521372 — neuroscience — Posted on 2023-06-29

245 Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by Derlin-1 through Maintenance of Adult Neurogenesis

Murao, N.; Matsuda, T.; Kadowaki, H.; Matsushita, Y.; Tanimoto, K.; Katagiri, T.; Nakashima, K.; Nishitoh, H.

10.1101/2023.04.27.538634 — neuroscience — Posted on 2023-06-29

246 Anatomy of a mega-radiation: Biogeography and niche evolution in Astragalus

Folk, R. A.; Charboneau, J.; belitz, m.; Singh, T.; Kates, H. R.; Soltis, D. E.; Soltis, P. S.; Guralnick, R. P.; Siniscalchi, C. M.

10.1101/2023.06.27.546767 — plant biology — Posted on 2023-06-29

247 Developing best practices for genotyping-by-sequencing analysis using linkage maps as benchmarks

Taniguti, C. H.; Taniguti, L. M.; Amadeu, R. R.; Lau, J.; Gesteira, G. d. S.; Oliveira, T. d. P.; Ferreira, G. C.; Pereira, G. d. S.; Byrne, D.; Mollinari, M.; Riera-Lizarazu, O.; Garcia, A. A. F.

10.1101/2022.11.24.517847 — bioinformatics — Posted on 2023-06-29

248 Skull and scalp segmentation in neonatal cerebral MRI using subject-specific probability models

Hokmabadi, E.; Abrishami Moghaddam, H.; Mohtasebi, M.; Kazemloo, A.; Gity, M.; Wallois, F.

10.1101/2022.05.06.490211 — bioengineering — Posted on 2023-06-29

249 Abiotic niche predictors of long-term trends in body mass and survival of Eastern Himalayan birds

Bharadwaj, A.; Chanda, R.; Rai, S.; Rai, M.; Biswakarma, A.; Munda, B.; Tamang, B.; Pradhan, D. K.; Srinivasan, U.

10.1101/2022.08.25.505219 — ecology — Posted on 2023-06-29

250 Inositol pyrophosphate dynamics reveals control of the yeast PHO starvation program through 1,5-IP8 and the SPX domain of Pho81

Chabert, V.; Kim, G.; Qiu, D.; Jamsheer K., M.; Michaillat Mayer, L.; Jessen, H. J.; Mayer, A.; Liu, G.

10.1101/2023.02.14.528555 — cell biology — Posted on 2023-06-29

251 Hippocampome.org v2.0: a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits

Wheeler, D. W.; Kopsick, J. D.; Sutton, N.; Tecuatl, C.; Komendantov, A. O.; Nadella, K.; Ascoli, G. A.

10.1101/2023.05.12.540597 — neuroscience — Posted on 2023-06-29

252 Mutual inclusivity improves decision-making by smoothing out choice's competitive edge

Leng, X.; Frömer, R.; Summe, T.; Shenhav, A.

10.1101/2023.05.12.540529 — neuroscience — Posted on 2023-06-29

253 Emotional memories are enhanced when reactivated in slow wave sleep, but impaired when reactivated in REM

Yuksel, C.; Denis, D.; Coleman, J.; Ren, B.; Oh, A.; Cox, R.; Morgan, A.; Sato, E.; Stickgold, R.

10.1101/2023.03.01.530661 — neuroscience — Posted on 2023-06-29

254 Optimizing anesthesia and delivery approaches for dosing into lungs of mice

Seo, Y.; Qiu, L.; Magnen, M.; Conrad, C.; Moussavi-Harami, S. F.; Looney, M. R.; Cleary, S. J.

10.1101/2023.02.01.526706 — physiology — Posted on 2023-06-29

255 Dynamics of activation in the voltage-sensing domain of Ci-VSP

Guo, S. C.; Shen, R.; Roux, B.; Dinner, A. R.

10.1101/2022.12.19.521128 — biophysics — Posted on 2023-06-29

256 Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals using a photoacoustic imaging scanner with a hemispherical detector array

Asao, Y.; Hirano, R.; Nagae, K.; Sekiguchi, H.; Aiso, S.; Watanabe, S.; Sato, M.; Yagi, T.; Kondoh, S. K.

10.1101/2023.06.19.545650 — bioengineering — Posted on 2023-06-29

257 Small molecule screen identifies non-catalytic USP3 chemical handle

Mann, M. K.; WOLF, E. Z.; Silva, M.; Wilson, B.; Wilson, D. J.; Harding, R. J.; Schapira, M.

10.1101/2023.03.01.530657 — biochemistry — Posted on 2023-06-29

258 Inhibition of auxin biosynthesis in early rice grains leads to extensive post-fertilisation grain abortion

Basunia, M. A.; Nonhebel, H. M.; Backhouse, D.; McMillan, M.

10.1101/2023.06.29.547002 — plant biology — Posted on 2023-06-29

259 Dynamic saccade context triggers more stable object-location binding

Lu, Z.; Golomb, J. D.

10.1101/2023.04.26.538469 — neuroscience — Posted on 2023-06-29

260 Insightful inference compensates for distorted perception

Mihali, A. L.; Broeker, M. D.; Ragalmuto, F. D. M.; Horga, G.

10.1101/2021.11.13.468497 — neuroscience — Posted on 2023-06-29

261 Histone deacetylase 3 plays a critical role in hypertension-induced kidney inflammation and fibrosis

An, C.; Jiao, B.; Du, H.; Tran, M.; Song, B.; Wang, P.; Hu, Z.; Zhou, D.; Wang, Y.

10.1101/2023.06.27.546796 — pathology — Posted on 2023-06-29

262 An RNA to rule them all: Critical steps in Lassa virus ribonucleoparticle assembly and recruitment

Saenger, L.; Williams, H. M.; Yu, D.; Vogel, D.; Kosinski, J.; Rosenthal, M.; Uetrecht, C.

10.1101/2023.02.09.527830 — biophysics — Posted on 2023-06-29

263 Chemically induced partial unfolding of the multifunctional Apurinic/apyrimidinic endonuclease 1

Rai, R.; Dawodu, O.; Johnson, S. M.; Vilseck, J. Z.; Kelley, M. R.; Ziarek, J. J.; Georgiadis, M. M.

10.1101/2023.06.29.547112 — biochemistry — Posted on 2023-06-29

264 Standing genetic variation and de novo mutations underlie parallel evolution of island bird phenotypes

Estandia, A.; Sendell-Price, A. T.; Robertson, B. C.; Clegg, S. M.

10.1101/2023.06.29.546893 — evolutionary biology — Posted on 2023-06-29

265 The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation

Xu, H.; Yuan, Z.; Qin, K.; Jiang, S.; Sun, L.

10.1101/2023.06.28.546966 — evolutionary biology — Posted on 2023-06-29

266 Complete zooplankton size spectra re-constructed from in situ imaging and Multinet data in the global ocean

SOVIADAN, Y. D.; Dugenne, M.; Drago, L.; Biard, T.; Trudnowska, E.; Romagnan, J.-B.; Jamet, J.-L.; Kiko, R.; Gorsky, G.; Stemmann, L.

10.1101/2023.06.29.547051 — ecology — Posted on 2023-06-29

267 Gle1 is required for tRNA to stimulate Dbp5 ATPase activity in vitro and to promote Dbp5 mediated tRNA export in vivo.

Rajan, A. A. N.; Asada, R.; Montpetit, B.

10.1101/2023.06.29.547072 — molecular biology — Posted on 2023-06-29

268 p53-Bad* in a Hepatocellular Carcinoma Mouse Model

Bowman, K. E. R.; Lu, P.; Lim, C. S.

10.1101/2023.06.29.547129 — molecular biology — Posted on 2023-06-29

269 Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)

Frieg, B.; Han, M.; Giller, K.; Dienemann, C.; Riedel, D.; Becker, S.; Andreas, L. B.; Griesinger, C.; Schröder, G. F.

10.1101/2023.06.28.546947 — molecular biology — Posted on 2023-06-29

270 The Unexpected Match: STAT3-NORAD Interaction, a Novel Link in Antiviral Defense

Argoetti, A.; Shalev, D.; Polyak, G.; Shima, N.; Biran, H.; Lahav, T.; Hashimshony, T.; Mandel-Gutfreund, Y.

10.1101/2023.06.29.546999 — molecular biology — Posted on 2023-06-29

271 Theoretical validation of growth curves for quantifying phage-bacteria interactions

Blazanin, M.; Vasen, E.; Jolis, C. V.; An, W.; Turner, P.

10.1101/2023.06.29.546975 — microbiology — Posted on 2023-06-29

272 A one-track model for spatiotemporal coordination of Bacillus subtilis septal cell wall synthesis

Whitley, K. D.; Grimshaw, J.; Karinou, E.; Stansfeld, P. J.; Holden, S.

10.1101/2023.06.29.547024 — microbiology — Posted on 2023-06-29

273 Processive movement of Staphylococcus aureus essential septal peptidoglycan synthases is independent of FtsZ treadmilling and drives cell constriction

Schaeper, S.; Brito, A. D.; Saraiva, B. M.; Squyres, G. R.; Holmes, M. J.; Garner, E. C.; Hensel, Z.; Henriques, R.; Pinho, M. G.

10.1101/2023.06.29.547026 — microbiology — Posted on 2023-06-29

274 Methylome evolution through lineage-dependent selection in the gastric pathogen Helicobacter pylori

Ailloud, F.; Gottschall, W.; Suerbaum, S.

10.1101/2023.06.29.547018 — microbiology — Posted on 2023-06-29

275 AMF-SporeChip provides new insights into arbuscular mycorrhizal fungal pre-symbiotic hyphal growth dynamics at the cellular level.

Richter, F.; Calonne-Salmon, M.; van der Heijden, M. G. A.; Declerck, S.; Stanley, C. E.

10.1101/2023.06.29.546436 — microbiology — Posted on 2023-06-29

276 Epigenetic changes and serotype-specific interferon-responses of lung epithelial cells in late post-influenza pneumococcal pneumonia

Boehme, J. D.; Jeron, A.; Schultz, K.; Melcher, L.; Schott, K.; Gelmez, E.; Kroeger, A.; Stegemann-Koniszewski, S.; Bruder, D.

10.1101/2023.06.28.546771 — immunology — Posted on 2023-06-29

277 Brain signatures indexing variation in internal processing during perceptual decision-making

Nakuci, J.; Samaha, J.; Rahnev, D.

10.1101/2023.01.10.523502 — neuroscience — Posted on 2023-06-29

278 Noninvasive theta burst stimulation of the human striatum enhances striatal activity and motor skill learning

Wessel, M. J.; Beanato, E.; Popa, T.; Windel, F.; Vassiliadis, P.; Menoud, P.; Beliaeva, V.; Violante, I. R.; Abderrahmane, H.; Dzialecka, P.; Park, C.-H.; Maceira-Elvira, P.; Morishita, T.; Cassara, A.; Steiner, M.; Grossman, N.; Neufeld, E.; Hummel, F. C.

10.1101/2022.10.28.514204 — neuroscience — Posted on 2023-06-29

279 Chromatin compaction and spatial organization in rice interphase nuclei

Dolezalova, A.; Berankova, D.; Kolackova, V.; Hribova, E.

10.1101/2023.06.28.546909 — plant biology — Posted on 2023-06-29

280 Tetraose steroidal glycoalkaloids from potato provide resistance against Alternaria solani and Colorado potato beetle

Wolters, P. J.; Wouters, D.; Tikunov, Y. M.; Ayilalath, S.; Kodde, L. P.; Strijker, M.; Caarls, L.; Visser, R. G. F.; Vleeshouwers, V. G. A. A.

10.1101/2022.09.28.509958 — plant biology — Posted on 2023-06-29

281 Uncovering Protein Ensembles: Automated Multiconformer Model Building for X-ray Crystallography and Cryo-EM

Wankowicz, S. A.; Ravikumar, A.; Sharma, S.; Riley, B.; Raju, A.; Hogan, D. W.; van den Bedem, H.; Keedy, D. A.; Fraser, J. S.

10.1101/2023.06.28.546963 — biophysics — Posted on 2023-06-29

282 Semi-automated retrieval of chemical and phylogenetic information from natural products literature

Coelho, A. C. L.; da Silva, R. R.

10.1101/2023.06.28.546864 — bioinformatics — Posted on 2023-06-29

283 Identification of three distinct cell populations for urate excretion in human kidney

Sakaguchi, Y. M.; Wiriyasermkul, P.; Matsubayashi, M.; Miyasaka, M.; Sakaguchi, N.; Sahara, Y.; Takasato, M.; Kinugawa, K.; Sugie, K.; Eriguchi, M.; Tsuruya, K.; Kuniyasu, H.; Nagamori, S.; Mori, E.

10.1101/2023.06.29.545826 — bioinformatics — Posted on 2023-06-29

284 Mammal life history strategies are strongly associated with environmental realms

Beccari, E.; Capdevila Lanzaco, P.; Salguero-Gomez, R.; Perez Carmona, C.

10.1101/2023.06.29.546851 — ecology — Posted on 2023-06-29

285 Maltodextrin administration ameliorates brain pathology in a mouse model of mitochondrial disease

Dominguez-Martinez, A.; Molina-Menor, E.; Blanco-Ramos, M.; Urpi, A.; Pereto, J.; Porcar, M.; Quintana, A.

10.1101/2023.06.28.546916 — neuroscience — Posted on 2023-06-29

286 Cell autonomous regulation of the activation of AgRP neurons by the melanocortin-3 receptor

Gui, Y.; Dahir, N. S.; Downing, G.; Sweeney, P.; Cone, R. D.

10.1101/2023.06.28.546874 — neuroscience — Posted on 2023-06-29

287 The long non-coding RNA LINDA restrains cellular collapse following DNA damage in Arabidopsis thaliana

Herbst, J.; Nagy, S. H.; Vercauteren, I.; De Veylder, L.; Kunze, R.

10.1101/2023.06.28.546876 — plant biology — Posted on 2023-06-29

288 Performance of Orbicella faveolata larval cohorts does not align with previously observed thermal tolerance of adult source populations

Zhang, Y.; Gantt, S. E.; Keister, E. F.; Elder, H.; Kolodziej, G.; Aguilar, C.; Studivan, M. S.; Williams, D. E.; Kemp, D. W.; Manzello, D. P.; Enochs, I. C.; Kenkel, C. D.

10.1101/2023.06.28.546780 — physiology — Posted on 2023-06-29

289 Visual-spatial dynamics drive adaptive social learning in immersive environments

Wu, C. M.; Deffner, D.; Kahl, B.; Meder, B.; Ho, M. H.; Kurvers, R. H.

10.1101/2023.06.28.546887 — animal behavior and cognition — Posted on 2023-06-29

290 Limited effects of dehydration on object discrimination in the novel object recognition paradigm in young and middle-aged male and female rats.

Santollo, J.; Rainer, I. L.; Swanz, L.; Steineker, M. H.; Holla, S.

10.1101/2023.06.28.546884 — animal behavior and cognition — Posted on 2023-06-29

291 Non-coding mutations at enhancer clusters contribute to pancreatic ductal adenocarcinoma

Patel, M. B.; Maniati, E.; Atanur, S. S.; Pal, D.; Rio-Machin, A.; Heward, J.; Kocher, H.; Fitzgibbon, J.; Madapura, P.; Wang, J.

10.1101/2023.06.28.546873 — genomics — Posted on 2023-06-29

292 A Glance into the Density of Transcriptomic Activity, Embodied by the HOX Genes, in Neonatal and Aging Dermal Cells

Ko, D.; Kim, M.; Nho, Y.-H.; Lee, D.-G.; Kang, S.; Han, K.; Mun, S.; Kim, M.

10.1101/2023.06.28.546883 — genomics — Posted on 2023-06-29

293 Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Diceros bicornis michaeli)

Mellya, R. V. K.; Hopcraft, J. G. C.; Mwakilema, W.; Eblate, E. M.; Mduma, S.; Mnaya, B.; Chuma, I.; Macha, E. S.; Wambura, D.; Fyumagwa, R.; Kilbride, E.; Mable, B. K.; Khan, A.

10.1101/2023.06.28.546899 — evolutionary biology — Posted on 2023-06-29

294 Fungal phylogeny reconstructed using heterogeneous models reveals new placement of Microsporidia

Riquelme-Medina, I.; McInerney, J.

10.1101/2023.06.28.546859 — evolutionary biology — Posted on 2023-06-29

295 Expanding the Evo-Devo Toolkit: Generation of 3D mammary tissue from diverse mammals

Kim, H. Y.; Sinha, I.; Sears, K. E.; Kuperwasser, C.; Rauner, G.

10.1101/2023.06.28.546911 — developmental biology — Posted on 2023-06-29

296 A modular approach to handle in-vivo drift correction for high-density extracellular recordings

Garcia, S.; Windolf, C.; Boussard, J.; Dichter, B.; Buccino, A. P.; Yger, P.

10.1101/2023.06.29.546882 — neuroscience — Posted on 2023-06-29

297 Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses

Micheva, K. D.; Gong, B.; Collman, F. C.; Weinberg, R. J.; Smith, S. J.; Trimmer, J.; Murray, K. D.

10.1101/2023.06.28.546920 — neuroscience — Posted on 2023-06-29

298 High-Intensity Interval Training Attenuates Impairment in Regulatory Protein Machinery of Mitochondrial Quality Control in Skeletal Muscle of Diet-Induced Obese Mice

Tincknell, J. B.; Kugler, B. A.; Spicuzza, H.; Yan, H.; You, T.; Zou, K.

10.1101/2023.06.28.546902 — physiology — Posted on 2023-06-29

299 nf-core/marsseq: systematic pre-processing pipeline for MARS-seq experiments

Proks, M.; Herrera, J. A. R.; Sedzinski, J.; Brickman, J. M.

10.1101/2023.06.28.546862 — bioinformatics — Posted on 2023-06-29

300 Development of a CMS Classifier for Clinical CRC Samples

Torang, A.; van de Weerd, S.; van Lammers, V.; van Hooff, S.; Koster, J.; Medema, J. P.

10.1101/2023.06.28.546869 — bioinformatics — Posted on 2023-06-29

301 Comparable analysis of multiple DNA double-strand break repair pathways in CRISPR-mediated endogenous tagging

Tei, C.; Hata, S.; Mabuchi, A.; Genova, M.; Okuda, S.; Ito, K. K.; Fukuyama, M.; Yamamoto, S.; Chinen, T.; Toyoda, A.; Kitagawa, D.

10.1101/2023.06.28.546861 — genomics — Posted on 2023-06-29

302 Evaluating Study Design Rigor in Preclinical Cardiovascular Research: A Replication Study

Jimenez, I. C.; Montenegro, G. C.; Zahiri, K.; Patel, D.; Mueller, A.

10.1101/2023.06.27.546731 — systems biology — Posted on 2023-06-29

303 Simultaneous Multi-Omics Analysis by Direct Infusion Mass Spectrometry (SMAD-MS)

Jiang, Y.; Salladay-Perez, I.; Momenzadeh, A.; Covarrubias, A. J.; Meyer, J. G.

10.1101/2023.06.26.546628 — systems biology — Posted on 2023-06-29

304 Is a Picture Worth 1,000 SNPs? Effects of User-Submitted Photographs on Ancestry Estimates from Direct-to-Consumer Canine Genetic Tests

Rando, H.; Graim, K.; Hampikian, G.; Greene, C. S.

10.1101/2023.06.28.546898 — genetics — Posted on 2023-06-29

305 Implementing a framework of carbon and nitrogen feedback responses into a plant resource allocation model

Holland, B. L.; Monk, N. A. M.; Clayton, R. H.; Osborne, C. P.

10.1101/2023.06.27.546727 — plant biology — Posted on 2023-06-29

306 Physiological adaptation to high irradiance in duckweeds depends on light habitat niche and is ecotype and species-specific.

Smith, K. E.; Cowan, L.; Taylor, B.; McAusland, L.; Heatley, M.; Murchie, E. H.

10.1101/2023.06.27.546714 — physiology — Posted on 2023-06-29

307 Dying of thirst: Osmoregulation by a hawkmoth pollinator in response to variability in ambient humidity and nectar availability

Dahake, A.; Persaud, S.; Jones, M. N.; Goyret, J.; Davidowitz, G.; Raguso, R. A.

10.1101/2023.06.27.546736 — physiology — Posted on 2023-06-29

308 Non-image forming vision as measured through ipRGC-mediated pupil constriction is not modulated by covert visual attention

Vilotijevic, A.; Mathot, S.

10.1101/2023.06.27.546729 — physiology — Posted on 2023-06-29

309 The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes

Matsumoto, C.; O'Dwyer, S. C.; Manning, D.; Hernandez-Hernandez, G.; Rhana, P.; Fong, Z.; Sato, D.; Clancy, C. E.; Vierra, N. C.; Trimmer, J. S.; Santana, L. F.

10.1101/2023.06.27.546725 — physiology — Posted on 2023-06-29

310 Phylogenetic placement of Ceratophyllum submersum based on a complete plastome sequence derived from nanopore long read sequencing data

Meckoni, S. N.; Nass, B.; Pucker, B.

10.1101/2023.06.27.546741 — genomics — Posted on 2023-06-29

311 Dendrimeric DNA Coordinate Barcoding Design for Spatial RNA Sequencing

Cao, J.; Zheng, Z.; Sun, D.; Chen, X.; Chen, R.; Lv, T.; An, Y.; Zheng, J.; Song, J.; Wu, L.; Yang, C.

10.1101/2023.06.26.546618 — genomics — Posted on 2023-06-29

312 Unveiling targeted cell-free DNA methylation regions through paired methylome analysis of tumor and normal tissues

Li, T.; Patel, K. B.; Yu, X.; Yao, S.; Wang, L.; Chung, C. H.; Wang, X.

10.1101/2023.06.27.546654 — genomics — Posted on 2023-06-29

313 Genomic insights into southern white rhinoceros ( Ceratotherium simum simum ) reproduction: revealing granulosa cell gene expression

Ruggeri, E.; Klohonatz, K.; Sirard, M.-A.; Durrant, B.; Coleman, S.

10.1101/2023.06.27.546732 — genomics — Posted on 2023-06-29

314 Sequence basis of transcription initiation in human genome

Dudnyk, K.; Shi, C.; Zhou, J.

10.1101/2023.06.27.546584 — genomics — Posted on 2023-06-29

315 The ChickenGTEx pilot analysis: a reference of regulatory variants across 28 chicken tissues

Guan, D.; Bai, Z.; Zhu, X.; Zhong, C.; Hou, Y.; Lan, F.; Diao, S.; Yao, Y.; Zhao, B.; Zhu, D.; Li, X.; Pan, Z.; Gao, Y.; Wang, Y.; Zou, D.; Wang, R.; Xu, T.; Sun, C.; Yin, H.; Teng, J.; Xu, Z.; Lin, Q.; Shi, S.; Shao, D.; Degalez, F.; Lagarrigue, S.; Wang, Y.; Wang, M.; Peng, M.; Rocha, D.; Charles, M.; Smith, J.; Watson, K.; Buitenhuis, A. J.; Sahana, G.; Lund, M. S.; Warren, W.; Frantz, L.; Larson, G.; Lamont, S. J.; Si, W.; Zhao, X.; Li, B.; Zhang, H.; Luo, C.; Shu, D.; Qu, H.; Luo, W.; Li, Z.; Nie, Q.; Zhang, X.; Zhang, Z.; Zhang, Z.; Liu, G. E.; Cheng, H.; Yang, N.; Hu, X.; Zhou, H.; Fang

10.1101/2023.06.27.546670 — genetics — Posted on 2023-06-29

Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.

10.1101/2023.06.27.546663 — genetics — Posted on 2023-06-29

317 Direct and indirect fitness effects of competition limit evolution of allelopathy in an invading plant

Honor, R.; Marcellus, M.; Colautti, R. I.

10.1101/2023.06.27.546761 — ecology — Posted on 2023-06-29

318 The Antitumor Activities of Anti-CD47 Antibodies Require Fc-FcγR interactions

Osorio, J. C.; Smith, P.; Knorr, D. A.; Ravetch, J.

10.1101/2023.06.29.547082 — immunology — Posted on 2023-06-29

319 A role for BCL6 in maintaining CX3CR1+ CD4+ T cells during helminth infection

Loredan, D. G.; Devlin, J. C.; Khanna, K.; Loke, P.

10.1101/2023.06.27.546755 — immunology — Posted on 2023-06-29

320 Two birds with one stone: human SIRPα nanobodies for functional modulation and in vivo imaging of myeloid cells

Wagner, T. R.; Blaess, S.; Leske, I.; Frecot, D. I.; Gramlich, M.; Traenkle, B.; Kaiser, P. D.; Seyfried, D.; Maier, S.; Rezza, A.; Sonego, F.; Thiam, K.; Pezzana, S.; Zeck, A.; Gouttefangeas, C.; Scholz, A. M.; Nueske, S.; Maurer, A.; Kneilling, M.; Pichler, B. J.; Sonanini, D.; Rothbauer, U.

10.1101/2023.06.27.546763 — immunology — Posted on 2023-06-29

321 Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers

Pizzato, H. A.; Alonso-Guallart, P.; Woods, J.; Johannesson, B.; Connelly, J. P.; Fehniger, T. A.; Atkinson, J.; Pruett-Miller, S. M.; Monsma, F. J.; Bhattacharya, D.

10.1101/2023.06.27.546594 — immunology — Posted on 2023-06-29

322 Inserting a Neuropixels probe into awake monkey cortex: two probes, two methods

Namima, T.; Kempkes, E.; Smith, B.; Pasupathy, A.

10.1101/2023.06.26.546631 — neuroscience — Posted on 2023-06-29

323 Zona incerta dopamine neurons encode motivational vigor in food seeking

Ye, Q.; Nunez, J.; Zhang, X.

10.1101/2023.06.29.547060 — neuroscience — Posted on 2023-06-29

324 Pixel-wise programmability enables dynamic high-SNR cameras for high-speed microscopy

Zhang, J.; Newman, J.; Wang, Z.; Qian, Y.; Guo, W.; Chen, Z. S.; Linghu, C.; Etienne-Cummings, R.; Fossum, E.; Boyden, E.; Wilson, M. A.

10.1101/2023.06.27.546748 — neuroscience — Posted on 2023-06-29

325 Molecular Signatures of Attention Networks

Schindler, H.; Jawinski, P.; Arnatkeviciute, A.; Markett, S.

10.1101/2023.06.29.547064 — neuroscience — Posted on 2023-06-29

326 Stochastic coding: a conserved feature of odor representations and its implications for odor discrimination

Srinivasan, S.; Daste, S.; Modi, M.; Turner, G.; Fleischmann, A.; Navlakha, S.

10.1101/2023.06.27.546757 — neuroscience — Posted on 2023-06-29

327 Two-color coincidence single-molecule pull-down for the specific detection of disease-associated protein aggregates

Saleeb, R. S.; Leighton, C.; Lee, J.-E.; O'Shaughnessy, J.; Jeacock, K.; Chappard, A.; Cumberland, R.; Ball, S. R.; Sunde, M.; Clarke, D. J.; Piche, K.; McPhail, J. A.; Louwrier, A.; Angers, R.; Gandhi, S.; Downey, P.; Kunath, T.; Horrocks, M. H.

10.1101/2023.06.27.546642 — neuroscience — Posted on 2023-06-29

328 Clinical Significance of the Stromatic Component in Ovarian Cancer: Quantity Over Quality in Outcome Prediction

Lou, E.; Clemente, V.; Grube, M.; Svedbom, A.; Nelson, A. C.; Blome, F.; Staebler, A.; Kommoss, S.; Bazzaro, M.

10.1101/2023.06.27.546712 — pathology — Posted on 2023-06-29

329 PAS domain of flagellar histidine kinase FlrB exhibits novel architecture, and binds Heme as sensory signal in unconventional fashion

Mukherjee, P.; Agarwal, S.; Basu Mallick, S.; Dasgupta, J.

10.1101/2023.06.29.547052 — biophysics — Posted on 2023-06-29

330 Peripheral linker mediates ACP's recognition of DH and stabilizes Mycobacterium tuberculosis FAS-I

Kumar, A.; Sharma, M.; Katkar, H. H.

10.1101/2023.06.27.546713 — biophysics — Posted on 2023-06-29

331 Prediction of tumor-specific splicing from somatic mutations as a source of neoantigen candidates

Lang, F.; Sorn, P.; Suchan, M.; Henrich, A.; Albrecht, C.; Koehl, N.; Beicht, A.; Riesgo-Ferreiro, P.; Holtsträter, C.; Schrörs, B.; Weber, D.; Löwer, M.; Sahin, U.; Ibn-Salem, J.

10.1101/2023.06.27.546494 — bioinformatics — Posted on 2023-06-29

332 Computational investigation of cis-1,4-polyisoprene binding to the latex clearing protein LcpK30

Abu Hassan, A.; Hanzevacki, M.; Pordea, A.

10.1101/2023.06.26.546638 — bioinformatics — Posted on 2023-06-29

333 Automated Extraction and Visualization of Metabolic Networks from Biomedical Literature Using a Large Language Model

Phongwattana, T.; Chan, J. H.

10.1101/2023.06.27.546560 — bioinformatics — Posted on 2023-06-29

334 Six novel nsSNPs affect RUNX1 gene may leading to Acute Myeloid Leukemia (AML) using Bioinformatics approach

Omer, D.; Ameer, T.; Alsheikh, T.; NjmEldin, A.; Abdalmonem, Z.; Suliman, H.; Agbash, A.; Hamad, H.; Alshareif, B. A.; Hassan, M. A.

10.1101/2023.06.26.546458 — bioinformatics — Posted on 2023-06-29

335 Clustering the Planet: An Exascale Approach to Determining Global Climatype Zones

Streich, J.; Furches, A.; Kainer, D.; Garcia, B. J.; Jones, P.; Romero, J.; Garvin, M. R.; Climer, S.; Thornton, P. E.; Joubert, W.; Jacobson, D.

10.1101/2023.06.27.546742 — bioinformatics — Posted on 2023-06-29

336 Mixed data analysis detected Endocrine Fibroblast Growth Factors (FGF19, FGF21, and FGF23) as Prognostic and Diagnostic Markers of Colorectal Neoplasia and Carcinoma

Rejali, L.; Piroozkhah, M.; Jahanbin, M.; Jalali, P.; Khanabadi, B.; Abkenar, E. D.; Tavallaei, M.; Niasar, M. S.; Hashemi, M.; Sadeghi, A.; Salehi, Z.; Nazemalhosseini-Mojarad, E.

10.1101/2023.06.27.546716 — bioinformatics — Posted on 2023-06-29

337 Aggregation Tool for Genomic Concepts (ATGC): A deep learning framework for somatic mutations and other sparse genomic measures

Anaya, J.; Sidhom, J.-W.; Mahmood, F.; Baras, A. S.

10.1101/2020.08.05.237206 — bioinformatics — Posted on 2023-06-29

338 Optimizing Proteomics Data Differential Expression Analysis via High-Performing Rules and Ensemble Inference

Peng, H.; Wang, H.; Kong, W.; Li, J.; Goh, W. W. B.

10.1101/2023.06.26.546625 — bioinformatics — Posted on 2023-06-29

339 Morc1 re-establishes heterochromatin on activated transposons and shapes the host transcriptome in gonocytes

Uneme, Y.; Maeda, R.; Nakayama, G.; Narita, H.; Takeda, N.; Hiramatsu, R.; Nishihara, H.; Nakato, R.; Kanai, Y.; Araki, K.; Siomi, M. C.; Yamanaka, S.

10.1101/2023.06.26.546627 — bioinformatics — Posted on 2023-06-29

340 A closer look at Type I left-handed β-helices provides a better understanding in their sequence-structure relationship: towards their rational design

Lebrun, V.; Faller, P.; Naude, M.

10.1101/2023.06.27.546660 — bioinformatics — Posted on 2023-06-29

341 Decreased efficacy of a COVID-19 vaccine due to mutations present in early SARS-CoV-2 variants of concern

Weidenbacher, P. A.; Friedland, N.; Sanyal, M.; Morris, M. K.; Do, J.; Hanson, C.; Kim, P. S.

10.1101/2023.06.27.546764 — biochemistry — Posted on 2023-06-29

342 Understanding consumers to inform market interventions for Singapore's shark fin trade

Choy, C.; Booth, H.; Verissimo, D.

10.1101/2023.06.27.545387 — ecology — Posted on 2023-06-29

343 F-actin and Myosin F control apicoplast elongation dynamics which drive apicoplast-centrosome association in Toxoplasma gondii

Devarakonda, P. M.; Sarmiento, V.; Heaslip, A. T.

10.1101/2023.06.27.546809 — cell biology — Posted on 2023-06-29

344 F-actin and Myosin F control apicoplast elongation dynamics which drive apicoplast-centrosome association in Toxoplasma gondii

Devarakonda, P. M.; Sarmiento, V.; Heaslip, A. T.

10.1101/2023.01.01.521342 — cell biology — Posted on 2023-06-29

345 Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility

Tan, K.; Chen, J.; Kaku, Y.; Wang, Y.; Donius, L.; Khan, R. A.; Li, X.; Richter, H.; Seaman, M. S.; Walz, T.; Hwang, W.; Reinherz, E. L.; Kim, M.

10.1101/2023.06.27.546734 — immunology — Posted on 2023-06-29

346 Attenuation of colitis-induced visceral hypersensitivity and pain by silencing TRPV1-expressing fibers in rat colon

Mazor, Y.; Engelmayer, N.; Nashashibi, H.; Rottenfusser, L.; Lev, S.; Binshtok, A. M.

10.1101/2023.06.27.546676 — neuroscience — Posted on 2023-06-29

347 The Cognitive Critical Brain: Modulation of Criticality in Task-Engaged Regions

Liu, X.; Fei, X.; Liu, J.

10.1101/2023.06.29.547080 — neuroscience — Posted on 2023-06-29

348 Experimental safety testing confirms that the NSAID nimesulide is toxic to Gyps vultures in India

Mathesh, K.; Manickam, K.; Mallord, J. W.; Mahendran, K.; M., A. K.; Saikia, D.; S., C. M.; V., B.; P., S. L.; Prakash, N.; Shringarpure, R.; Pawde, A.; Green, R. E.; Prakash, V.

10.1101/2023.06.27.546673 — pharmacology and toxicology — Posted on 2023-06-29

349 Sse1, Hsp110 chaperone of yeast, controls the cellular fate during Endoplasmic Reticulum-stress

Jha, M. P.; Kumar, V.; Sharma, L.; Ghosh, A.; Mapa, K.

10.1101/2023.06.29.547006 — cell biology — Posted on 2023-06-29

350 Covering Hierarchical Dirichlet Mixture Models on binary data to enhance genomic stratifications in Onco-Hematology

Dall'Olio, D.; Sträng, E.; Turki, A. T.; Tettero, J. M.; Barbus, M.; Schulze-Rath, R.; Elicegui, J. M.; Matteuzzi, T.; Merlotti, A.; Carota, L.; Sala, C.; Della Porta, M. G.; Giampieri, E.; Hernandez-Rivas, J. M.; Bullinger, L.; Castellani, G.

10.1101/2023.06.26.546639 — cancer biology — Posted on 2023-06-29

351 Normal gastric tissue Helicobacter pylori infection is associated with epigenetic age acceleration, increased mitotic tick rate, tissue cell composition, and Natural Killer cell methylation alterations

Vlasac, I. M.; Salas, L. A.; Christensen, B. C.

10.1101/2023.06.28.546926 — cancer biology — Posted on 2023-06-29

352 Differences in Relevant Physicochemical Properties Correlate with Synergistic Activity of Antimicrobial Peptides

Medvedeva, A.; Teimouri, H.; Kolomeisky, A.

10.1101/2023.06.27.546817 — biophysics — Posted on 2023-06-29

353 Competitive specific anchorage of molecules onto surfaces: quantitative control of grafting densities and contamination by free anchors

Kirichuk, O.; Srimasorn, S.; Zhang, X.; Roberts, A. R. E.; Coche-Guerente, L.; Kwok, J. C. F.; Bureau, L.; Debarre, D.; Richter, R. P.

10.1101/2023.06.27.546772 — biophysics — Posted on 2023-06-29

354 Lipid droplets as substrates for protein phase separation

Kamatar, A.; Bravo, J. P. K.; Yuan, F.; Wang, L.; Lafer, E. M.; Taylor, D. W.; Stachowiak, J.; Parekh, S. H.

10.1101/2023.06.28.546804 — biophysics — Posted on 2023-06-29

355 3D Cell Cultures Amplify Diffusion Signals

Arjmandi, H.; Kanebratt, K. P.; Vilen, L.; Gennemark, P.; Noel, A.

10.1101/2023.06.28.546952 — biophysics — Posted on 2023-06-29

356 Mn2+-Induced Structural Flexibility Enhances the Entire Catalytic Cycle and the Cleavage of Mismatches in Prokaryotic Argonaute Proteins

Zheng, L.; Zan, B.; Yang, Y.; Zhou, B.; Li, N.; Wu, B.; Jiang, F.; Feng, Y.; Liu, Q.; Hong, L.

10.1101/2023.06.28.546964 — biophysics — Posted on 2023-06-29

357 Coordination of transporter, cargo, and membrane properties during non-vesicular lipid transport.

Koukalova, A.; Eisenreichova, A.; Rozycki, B.; Boura, E.; Humpolickova, J.

10.1101/2023.06.28.546834 — biophysics — Posted on 2023-06-29

358 Accurate and Efficient 3D Reconstruction of Right Heart Shape and Motion from Multi-Series Cine-MRI

Renzi, F.; Vergara, C.; Fedele, M.; Giambruno, V.; Quarteroni, A.; Puppini, G.; Luciani, G. B.

10.1101/2023.06.28.546872 — bioengineering — Posted on 2023-06-29

359 Porous membrane electrical cell-substrate impedance spectroscopy for versatile assessment of biological barriers in vitro

Chebotarev, O.; Ugodnikov, A.; Simmons, C. A.

10.1101/2023.06.26.546641 — bioengineering — Posted on 2023-06-29

360 A drop dispenser for simplifying on-farm detection of foodborne pathogens

Ranjbaran, M.; Kaur, S.; Wang, J.; Raut, B.; Verma, M. S.

10.1101/2023.06.28.546938 — bioengineering — Posted on 2023-06-29

361 Proteins differentially expressed between pathogenic and non-pathogenic Entamoeba histolytica clones influence pathogenicity by different mechanisms

Anders, J.; König, C.; Lender, C.; Hellhund, A.; Nehls, S.; Shalabi, I.; Honecker, B.; Lorenzen, S.; Meyer, M.; Matthiesen, J.; Cadar, D.; Roeder, T.; Metwally, N. G.; Lotter, H.; Bruchhaus, I.

10.1101/2023.06.29.547007 — cell biology — Posted on 2023-06-29

362 A cellular and spatial atlas of TP53-associated tissue remodeling in lung adenocarcinoma

Zhao, W.; Kepecs, B.; Mahadevan, N. R.; Segerstolpe, A.; Weirather, J. L.; Besson, N. R.; Giotti, B.; Soong, B. Y.; Li, C.; Vigneau, S.; Slyper, M.; Wakiro, I.; Jane-Valbuena, J.; Ashenberg, O.; Rotem, A.; Bueno, R.; Rozenblatt-Rosen, O.; Pfaff, K.; Rodig, S.; Hata, A. N.; Regev, A.; Johnson, B. E.; Tsankov, A. M.

10.1101/2023.06.28.546977 — cancer biology — Posted on 2023-06-29

363 Th17 cells target the metabolic miR-142-5p-SDHC/SDHD axis promoting invasiveness and progression of cervical cancers

Pohlers, M.; Gies, S.; Taenzer, T.; Stroeder, R.; Theobald, L.; Ludwig, N.; Kim, Y.-J.; Bohle, R.; Solomayer, E. F.; Meese, E.; Hart, M.; Walch-Rueckheim, B.

10.1101/2023.06.29.547020 — cancer biology — Posted on 2023-06-29

364 Targeting Ribosome Biogenesis as a Novel Therapeutic Approach to Overcome EMT-related Chemoresistance in Breast Cancer.

Ban, Y.; Zou, Y.; Lee, S. B.; Bednarczyk, R. B.; Sheng, J.; Cao, Y.; Wong, S. T. C.; Gao, D.

10.1101/2023.06.28.546927 — cancer biology — Posted on 2023-06-29

365 Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics

Walker, T. J.; Reyes-Alvarez, E.; Hyndman, B. D.; Sugiyama, M. G.; Oliveira, L. C. B.; Rekab, A. N.; Crupi, M. J. F.; Cabral-Dias, R.; Guo, Q.; Dahia, P. L. M.; Richardson, D. S.; Antonescu, C. N.; Mulligan, L. M.

10.1101/2023.06.28.546955 — cancer biology — Posted on 2023-06-29

366 Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis

Shiau, C.; Cao, J.; Gregory, M. T.; Gong, D.; Yin, X.; Cho, J.-W.; Wang, P. L.; Su, J.; Wang, S.; Reeves, J. W.; Kim, T. K.; Kim, Y.; Guo, J. A.; Lester, N. A.; Schurman, N.; Barth, J. L.; Weissleder, R.; Jacks, T.; Qadan, M.; Hong, T. S.; Wo, J. Y.; Roberts, H.; Beechem, J. M.; Fernandez-del Castillo, C.; Mino-Kenudson, M.; Ting, D. T.; Hemberg, M.; Hwang, W. L.

10.1101/2023.06.28.546848 — cancer biology — Posted on 2023-06-29

367 All-optical mapping of cAMP transport reveals rules of sub-cellular localization

Xiang, K. M.; Park, P.; Koren, S. A.; Hayward, R. F.; Cohen, A. E.

10.1101/2023.06.27.546633 — biophysics — Posted on 2023-06-29

368 Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility

Boehringer, D.; Bauer, A.; Moravec, I.; Bischof, L.; Kah, D.; Mark, C.; Grundy, T. J.; Goerlach, E.; O'Neill, G. M.; Budday, S.; Strissel, P.; Strick, R.; Malandrino, A.; Gerum, R.; Mak, M.; Rausch, M.; Fabry, B.

10.1101/2023.06.28.546896 — biophysics — Posted on 2023-06-29

369 Genetically-encoded probes to determine nonspecific hydrophobic and electrostatic binding in cells

Zuo, W.; Huang, M.-R.; Schmitz, F.; Boersma, A. J.

10.1101/2023.06.27.546658 — biophysics — Posted on 2023-06-29

370 Efficient Visual Perception of Human-Robot Walking Environments Using Semi-Supervised Learning

Kuzmenko, D.; Tsepa, O.; Kurbis, G.; Mihailidis, A.; Laschowski, B.

10.1101/2023.06.28.546903 — bioengineering — Posted on 2023-06-29

371 Neuronal Spike Shapes (NSS): a simple approach to study electrophysiological data for heterogeneity investigation.

Martini, L.; Amprimo, G.; Di Carlo, S.; Olmo, G.; Ferraris, C.; Savino, A.; Bardini, R.

10.1101/2023.06.28.546812 — bioengineering — Posted on 2023-06-29

372 Nanoparticle endocytosis is driven by monocyte phenotype rather than nanoparticle size under high shear flow conditions

Aldarondo, D.; Hunyh, C.; Dickey, L.; Bilynsky, C. S. M.; Lee, Y.; Wayne, E. C.

10.1101/2023.06.29.547038 — bioengineering — Posted on 2023-06-29

373 Chirality-Enhanced Transport and Drug Delivery of Graphene Nanocarriers to Tumor-like Cellular Spheroid

Jeon, H.; Zhu, R.; Kim, G.; Wang, Y.

10.1101/2023.06.27.546698 — bioengineering — Posted on 2023-06-29

374 Decoding the comprehensive substrate-specificity and evidence of altered site-specific collagen prolyl-3-hydroxylation, lysyl-hydroxylation, and lysyl O-glycosylation in P4ha1 and P4ha2 deleted mutant mice

Sarohi, V.; Basak, T.

10.1101/2023.06.28.546985 — biochemistry — Posted on 2023-06-29

375 Arylamine N-acetyltransferase-1 reveals a subpopulation of ALS patients with altered metabolic capacity

Minchin, R.; Choudhury, C.; Allen, S.; Gill, M. K.; Garton, F.; Restuardi, R.; Butcher, N. J.; Ngo, S.; Steyn, F. J.

10.1101/2023.06.29.546993 — biochemistry — Posted on 2023-06-29

376 Genome-wide transcriptome analysis reveals the diversity and function of long non-coding RNAs in dinoflagellates

Chen, Y.; Dougan, K. E.; Nguyen, Q.; Bhattacharya, D.; Chan, C. X.

10.1101/2023.06.27.546665 — genomics — Posted on 2023-06-29

377 Liver-specification of human iPSC-derived endothelial cells transplanted into mouse liver

Yap, K. K.; Schroeder, J.; Gerrand, Y.-W.; Kong, A.; Fox, A. M.; Knowles, B.; Banting, S. W.; Elefanty, A. K.; Stanley, E. G.; Yeoh, G. C.; Lockwood, G. P.; Cogger, V. C.; Morrison, W. A.; Polo, J. M.; Mitchell, G. M.

10.1101/2023.06.28.546913 — cell biology — Posted on 2023-06-29

378 A rapid, inexpensive, non-lethal method for detecting disseminated neoplasia in a bivalve

Vandepas, L. E.; Crim, R. N.; Gilbertson, E.; Yonemitsu, M. A.; Unsell, E.; Metzger, M. J.; Lacy-Hulbert, A.; Goetz, F. W.

10.1101/2023.06.28.544680 — cell biology — Posted on 2023-06-29

379 A benchmark of optimization solvers for genome-scale metabolic modeling

Machado, D.

10.1101/2023.04.11.536343 — systems biology — Posted on 2023-06-29

380 Combination of NY-ESO-1-TCR-T-cells coengineered to secrete SiRPalpha decoys with anti-tumor antibodies to augment macrophage phagocytosis

Stefanidis, E.; Semilietof, A.; Pujol, J.; Seijo, B.; Scholten, K.; Zoete, V.; Michielin, O.; Sandaltzopoulos, R.; Coukos, G.; Irving, M.

10.1101/2023.06.27.546523 — bioengineering — Posted on 2023-06-29

381 Differential population coding of natural movies through spike counts and temporal sequences

Sotomayor-Gomez, B.; Battaglia, F.; Vinck, M.

10.1101/2023.06.27.546669 — neuroscience — Posted on 2023-06-29

382 A shared linguistic space for transmitting our thoughts from brain to brain in natural conversations

Zada, Z.; Goldstein, A. Y.; Michelmann, S.; Simony, E.; Price, A.; Hasenfratz, L.; Barham, E.; Zadbood, A.; Doyle, W.; Friedman, D.; Dugan, P.; Melloni, L.; Devore, S.; Flinker, A.; Devinsky, O.; Nastase, S. A.; Hasson, U.

10.1101/2023.06.27.546708 — neuroscience — Posted on 2023-06-29

383 Acoustically evoked K-complexes are sufficient to boost verbal memory consolidation during sleep

Leach, S.; Krugliakova, E.; Sousouri, G.; Snipes, S.; Scorucak, J.; Schuehle, S.; Mueller, M.; Ferster, M. L.; Da Poian, G.; Karlen, W.; Huber, R.

10.1101/2023.06.29.546822 — neuroscience — Posted on 2023-06-29

384 Task-specific invariant representation in auditory cortex

Heller, C. R.; Hamersky, G. R.; David, S. V.

10.1101/2023.06.29.547009 — neuroscience — Posted on 2023-06-29

385 Dissociable mechanistic contributions of limb and task related errors during human sensorimotor learning

Oza, A.; Kumar, A.; Sharma, A.; Mutha, P. K.

10.1101/2020.11.13.381285 — neuroscience — Posted on 2023-06-29

386 A SEVA-based, CRISPR-Cas3-assisted genome engineering approach for Pseudomonas with efficient vector curing

Lammens, E.-M.; Volke, D. C.; Schroven, K.; Voet, M.; Kerremans, A.; Lavigne, R.; Hendrix, H.

10.1101/2023.06.29.547033 — synthetic biology — Posted on 2023-06-29

387 Repurposing the dark genome. IV - noncoding proteins

Nayak, S.; Dhar, P. K.

10.1101/2023.06.29.547021 — synthetic biology — Posted on 2023-06-29

388 Scalable Integration of Multiomic Single Cell Data Using Generative Adversarial Networks

Giansanti, V.; Giannese, F.; Botrugno, O. A.; Gandolfi, G.; Balestrieri, C.; Antoniotti, M.; Tonon, G.; Cittaro, D.

10.1101/2023.06.26.546547 — bioinformatics — Posted on 2023-06-29

389 CoPheScan: phenome-wide association studies accounting for linkage disequilibrium

Manipur, I.; Reales, G.; Sul, J. H.; Shin, M. K.; Longerich, S.; Cortes, A.; Wallace, C.

10.1101/2023.06.29.546856 — genetics — Posted on 2023-06-29

390 Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration and suppress invasiveness, migration, and proliferation of melanoma cells

Katkat, E.; Demirci, Y.; Heger, G.; Karagulle, D.; Papatheodorou, I.; Brazma, A.; Ozhan, G.

10.1101/2022.03.11.483949 — developmental biology — Posted on 2023-06-29

391 A Dual Color Pax7 and Myf5 In Vivo Reporter to Investigate Muscle Stem Cell Heterogeneity in Regeneration and Aging

Ancel, S.; Michaud, J.; Sizzano, F.; Tauzin, L.; Oliveira, M.; Migliavacca, E.; Dammone, G.; Karaz, S.; Sanchez-Garcia, J. L.; Metairon, S.; Jacot, G.; Bentzinger, C. F.; Feige, J. N.; Stuelsatz, P.

10.1101/2023.06.19.545587 — cell biology — Posted on 2023-06-29

392 Elevated concentrations of polymyxin B elicit a biofilm-specific resistance mechanism in Vibrio cholerae

Pauze-Foixet, J.; Duperthuy, M.

10.1101/2023.06.26.546579 — microbiology — Posted on 2023-06-29

393 Multimodal acoustic-electric trigeminal nerve stimulation modulates conscious perception

Wu, M.; Auksztulewicz, R.; Riecke, L.

10.1101/2023.03.21.533632 — neuroscience — Posted on 2023-06-29

394 Propofol Mediated Unconsciousness Disrupts Progression of Sensory Signals through the Cortical Hierarchy

Tauber, J. M.; Brincat, S. L.; Stephen, E. P.; Donoghue, J. A.; Kozachkov, L.; Brown, E. N.; Miller, E. K.

10.1101/2023.06.25.546463 — neuroscience — Posted on 2023-06-29

395 Spatiotemporal Mapping of Brain Cilia Length and Orientation Reveals Region-Specific Oscillation

Monfared, R. V.; Abdelkarim, S.; Derdeyn, P.; Chen, K.; Wu, H.; Leong, K.; Chang, T.; Lee, J.; Versales, S.; Nauli, S.; Beier, K.; Baldi, P.; Alachkar, A.

10.1101/2023.06.28.546950 — neuroscience — Posted on 2023-06-29

396 Treating muscle and brain alike: benefits of GSK3 inhibition in mdx mice

Marcella, B. M.; Copeland, E. N.; Hamstra, S. I.; Hockey, B.; Braun, J. L.; Geromella, M. S.; Whitley, K. C.; Watson, C. J.; Baranowski, B. J.; Maddalena, L. A.; Silvera, S.; Baranowski, R. W.; Ochoa, E. C.; Wasilewicz, L. J.; Crozier, R. W.; Cleverdon, R. E.; Beaudette, S. M.; Vandenboom, R.; Roy, B. D.; Stuart, J. A.; MacNeil, A. J.; MacPherson, R. E.; Fajardo, V.

10.1101/2022.02.16.480726 — physiology — Posted on 2023-06-29

397 Scalable Integration of Multiomic Single Cell Data Using Generative Adversarial Networks

Giansanti, V.; Giannese, F.; Botrugno, O. A.; Gandolfi, G.; Balestrieri, C.; Antoniotti, M.; Tonon, G.; Cittaro, D.

10.1101/2023.06.26.546547 — bioinformatics — Posted on 2023-06-29

398 Ketone Bodies in Right Ventricular Failure: A Unique Therapeutic Opportunity

Blake, M.; Puchalska, P.; Kazmirczak, F.; Thenappan, T.; Crawford, P.; Prins, K.

10.1101/2023.04.26.538410 — biochemistry — Posted on 2023-06-29

399 GADMA2: more efficient and flexible demographic inference from genetic data

Noskova, E.; Abramov, N.; Iliutkin, S.; Sidorin, A.; Dobrynin, P.; Ulyantsev, V.

10.1101/2022.06.14.496083 — bioinformatics — Posted on 2023-06-29

400 A stochastic analysis of the interplay between antibiotic dose, mode of action, and bacterial competition in the evolution of antibiotic resistance

Czuppon, P.; Day, T.; Debarre, F.; Blanquart, F.

10.1101/2023.02.20.529188 — evolutionary biology — Posted on 2023-06-29

401 Provision of essential resources as a persistence strategy in food webs

Raatz, M.

10.1101/2023.01.27.525839 — ecology — Posted on 2023-06-29

402 SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes

Granados, A.; Zamperoni, M.; Rapone, R.; Bouyioukos, C.; Del Maestro, L.; Joliot, V.; Albini, S.; Ait-Si-Ali, S.

10.1101/2023.06.28.546840 — cell biology — Posted on 2023-06-29

403 Inter individual variability in neuronal expression of heat shock protein genes predicts stress survival in Caenorhabditis elegans.

Todtenhaupt, P.; Murdoch, S.; Vallejos, C. A.; Casanueva, M. O.; Chauve, L.

10.1101/2023.06.28.546835 — molecular biology — Posted on 2023-06-29

404 Unidirectional expression of enhancers with cell type-dependent direction of transcription

Agrawal, S.; Kanamaru, E.; Saito, Y.; Ishikawa, F.; de Hoon, M. J. L.

10.1101/2023.06.27.546647 — genomics — Posted on 2023-06-29

405 Joint profiling of multiplex chromatin interactions, gene expression, and RNA-chromatin associations in single cells of the human brain

Luo, Z.; Wen, X.; Zhao, W.; Nguyen, T.; Wan, X.; Richard, J. L. C.; Zhong, S.

10.1101/2023.06.28.546457 — genomics — Posted on 2023-06-29

406 The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution

Eleftheriadi, K.; Guiglielmoni, N.; Salces-Ortiz, J.; Vargas-Chavez, C.; Martinez-Redondo, G. I.; Gut, M.; Flot, J.-F.; Schmidt-Rhaesa, A.; Fernandez, R.

10.1101/2023.06.26.546503 — evolutionary biology — Posted on 2023-06-29

407 Human Neuronal Excitation/Inhibition Balance Explains and Predicts Neurostimulation Induced Learning Benefits

van Bueren, N. E. R.; van der Ven, S. H. G.; Hochman, S.; Sella, F.; Cohen Kadosh, R.

10.1101/2022.04.29.489988 — neuroscience — Posted on 2023-06-29

408 Bactabolize: A tool for high-throughput generation of bacterial strain-specific metabolic models

Vezina, B.; Watts, S. C.; Hawkey, J.; Cooper, H. B.; Judd, L. M.; Jenney, A.; Monk, J. M.; Holt, K. E.; Wyres, K. L.

10.1101/2023.02.26.530115 — bioinformatics — Posted on 2023-06-29

409 Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals using a photoacoustic imaging scanner with a hemispherical detector array

Asao, Y.; Hirano, R.; Nagae, K.; Sekiguchi, H.; Aiso, S.; Watanabe, S.; Sato, M.; Yagi, T.; Kondoh, S. K.

10.1101/2023.06.19.545650 — bioengineering — Posted on 2023-06-29

410 Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects

Kasela, S.; Aguet, F.; Kim-Hellmuth, S.; Brown, B. C.; Nachun, D. C.; Tracy, R. P.; Durda, P.; Liu, Y.; Taylor, K. D.; Johnson, W. C.; Van Den Berg, D.; Gabriel, S.; Gupta, N.; Smith, J. D.; Blackwell, T. W.; Rotter, J. I.; Ardlie, K. G.; Manichaikul, A.; Rich, S. S.; Barr, R. G.; Lappalainen, T.

10.1101/2023.06.26.546528 — genetics — Posted on 2023-06-29

411 Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis

Catta-Preta, R.; Lindtner, S.; Ypsilanti, A.; Price, J.; Abnousi, A.; Su-Feher, L.; Wang, Y.; Juric, I.; Jones, I.; Akiyama, J.; Hu, M.; Shen, Y.; Visel, A.; Pennacchio, L.; Dickel, D.; Rubenstein, J.; Nord, A.

10.1101/2023.06.28.546894 — developmental biology — Posted on 2023-06-29

412 Cellular iron governs the host response to malaria

Wideman, S. K.; Frost, J. N.; Richter, F. C.; Naylor, C.; Lopes, J. M.; Viveiros, N.; Teh, M. R.; Preston, A. E.; White, N.; Yusuf, S.; Draper, S.; Armitage, A. E.; Duarte, T. L.; Drakesmith, H.

10.1101/2023.02.05.527208 — immunology — Posted on 2023-06-29

413 Neural representation dynamics reveal computational principles of cognitive task learning

Mill, R. D.; Cole, M. W.

10.1101/2023.06.27.546751 — neuroscience — Posted on 2023-06-29

414 Memory-specific encoding activities of the ventral tegmental area dopamine and GABA neurons

Glykos, V.; Fujisawa, S.

10.1101/2023.06.28.546967 — neuroscience — Posted on 2023-06-29

415 Spatiotemporal Mapping of brain cilia length and orientation reveals region-specific Oscillation

Monfared, R. V.; Abdelkarim, S.; Derdeyn, P.; Chen, K.; Wu, H.; Leong, K.; Chang, T.; Lee, J.; Versales, S.; Nauli, S.; Beier, K.; Baldi, P.; Alachkar, A.

10.1101/2023.06.28.546950 — neuroscience — Posted on 2023-06-29

416 Prediction tendency, eye movements, and attention in a unified framework of neural speech tracking

Schubert, J.; Gehmacher, Q.; Schmidt, F.; Hartmann, T.; Weisz, N.

10.1101/2023.06.27.546746 — neuroscience — Posted on 2023-06-29

417 Encoding manual dexterity through modulation of intrinsic alpha band connectivity

Maddaluno, O.; Della Penna, S.; Pizzuti, A.; Spezialetti, M.; Corbetta, M.; de Pasquale, F.; Betti, V.

10.1101/2023.06.27.546709 — neuroscience — Posted on 2023-06-29

418 Polygenic risk score prediction accuracy convergence

Henches, L.; Kim, J.; Yang, Z.; Rubinacci, S.; Pires, G.; Albinana, C.; Boetto, C.; Julienne, H.; Frouin, A.; Auvergne, A.; Suzuki, Y.; Djebali, S.; Delaneau, O.; Ganna, A.; Vilhjalmsson, B.; Prive, F.; Aschard, H.

10.1101/2023.06.27.546518 — genetics — Posted on 2023-06-29

419 No evidence for song evolution influencing speciation patterns in honeyeaters

Hay, E. M.; Chown, S. L.; McGee, M. D.

10.1101/2023.06.27.546781 — evolutionary biology — Posted on 2023-06-29

420 Predictions in language adapt across contexts and individuals

Jano, S. L.; Cross, Z.; Chatburn, A.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.

10.1101/2023.05.08.539915 — neuroscience — Posted on 2023-06-28

421 Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors

Enriquez Traba, J.; Yarur, H. E.; Flores, R. J.; Weil, T.; Roy, S.; Usdin, T. B.; LaGamma, C. T.; Arenivar, M.; Wang, H.; Tsai, V. S.; Moritz, A. E.; Sibley, D. R.; Moratalla, R.; Freyberg, Z.; Tejeda, H. A.

10.1101/2023.06.27.546539 — neuroscience — Posted on 2023-06-28

422 Distinct Neurodevelopmental Patterns and Intermediate Integration-Based Predictive Modeling in Autism Spectral Disorder

Wang, Y.; Ma, S.; Ma, R.; Xiao, L.; Wei, Y.; Pan, Y.

10.1101/2023.06.26.546426 — neuroscience — Posted on 2023-06-28

423 Implicit reward-based motor learning

van Mastrigt, N. M.; Tsay, J. S.; Wang, T.; Avraham, G.; Abram, S. J.; van der Kooij, K.; Smeets, J.; Ivry, R. B.

10.1101/2023.06.27.546738 — neuroscience — Posted on 2023-06-28

424 Cytotoxic Activity Of A New Isoform L-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom In Human Leukemic HL60 Cells

Heleno, M. A. G.; Nowill, A.; Carvalho, J. E.; Suni-Curasi, D. L.; Vilca-Quispe, J.; Ponce-Fuentes, E. A.; Obando-Pereda, G.; Ponce-Soto, L. A.

10.1101/2020.01.15.907758 — pharmacology and toxicology — Posted on 2023-06-28

425 A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

Liang, S.; Tran, E.; Du, X.; Dong, J.; Sudholz, H.; Chen, H.; Qu, Z.; Huntington, N.; Babon, J.; Kershaw, N.; Zhang, Z.-Y.; Baell, J.; Wiede, F.; Tiganis, T.

10.1101/2023.06.16.545220 — cancer biology — Posted on 2023-06-28

426 Leading an urban invasion: risk-sensitive learning is a winning strategy

Breen, A. J.; Deffner, D.

10.1101/2023.03.19.533319 — animal behavior and cognition — Posted on 2023-06-28

427 Geographic variation of the for gene reveals signatures of local adaptation in Drosophila melanogaster

Perez, D. J. P.

10.1101/2023.02.19.529142 — evolutionary biology — Posted on 2023-06-28

428 Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals

Crapart, C.; Scott, Z. C.; Konno, T.; Sharma, A.; Bailey, D. M.; Avezov, E.; Koslover, E. F.

10.1101/2023.06.23.546357 — cell biology — Posted on 2023-06-28

429 Conserved Biophysical Compatibility Among the Highly Variable Germline-Encoded Regions Shapes TCR-MHC Interactions

Boughter, C. T.; Meier-Schellersheim, M.

10.1101/2022.12.07.519507 — immunology — Posted on 2023-06-28

430 The orientation of choroidal macrophage polarization significantly influences the development of myopia in murine models

Hou, J.; Ikeda, S.-i.; Mori, K.; Jeong, H.; Torii, H.; Negishi, K.; Tsubota, K.; Kurihara, T.

10.1101/2023.06.12.544445 — immunology — Posted on 2023-06-28

431 Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal-Glial Synapses and Reduced Expression in Nlgn3R451C Mice

Herath, M.; Cho, E.; Franks, A. E.; Bornstein, J. C.; Hill-Yardin, E. L.

10.1101/2022.05.02.490237 — neuroscience — Posted on 2023-06-28

432 The alternative sigma factor RpoD4 pulses at division and links the circadian clock and the cell cycle in Synechococcus elongatus

Ye, C.; Saez, T.; Das, A. K.; Martins, B. M. C.; Locke, J. C. W.

10.1101/2023.06.28.546855 — systems biology — Posted on 2023-06-28

433 Light-induced condensates show accumulation-prone and less dynamic properties in the nucleus compared to the cytoplasm.

Hamada, Y.; Kitamura, A.

10.1101/2023.06.07.544154 — biophysics — Posted on 2023-06-28

434 Acquired Cross-resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC paralogs

Pal Choudhuri, S.; Girard, L.; Lim, J. Y. S.; Wise, J. F.; Freitas, B.; Yang, D.; Wong, E.; Hamilton, S.; Chien, V.; Phat, S.; Gilbreath, C.; Zhong, J.; Myers, D. T.; Christensen, C. L.; Stanzione, M.; Wong, K.-K.; Farago, A. F.; Meador, C. B.; Dyson, N. J.; Lawrence, M. S.; Wu, S.; Drapkin, B. J.

10.1101/2023.06.23.546278 — cancer biology — Posted on 2023-06-28

435 Uncovering Protein Ensembles: Automated Multiconformer Model Building for X-ray Crystallography and Cryo-EM

Wankowicz, S. A.; Ravikumar, A.; Sharma, S.; Riley, B.; Raju, A.; Hogan, D.; van den Bedem, H.; Keedy, D. A.; Fraser, J. S.

10.1101/2023.06.28.546963 — biophysics — Posted on 2023-06-28

436 Heuristics for the De Bruijn Graph Sequence Mapping Problem

Rocha, L. B.; Adi, S. S.; Araujo, E.

10.1101/2023.02.05.527069 — bioinformatics — Posted on 2023-06-28

437 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein

Zuber, P. K.; Said, N.; Hilal, T.; Wang, B.; Loll, B.; Gonzlez-Higueras, J.; Ramirez-Sarmiento, C. A.; Belogurov, G. A.; Artsimovitch, I.; Wahl, M.; Knauer, S. H.

10.1101/2023.06.26.546588 — biochemistry — Posted on 2023-06-28

438 Electron microscopic and crystallographic studies of bacteriophage Sf6 procapsid-like particles assembled from heterologously expressed capsid protein gp5

Tang, L.; Zhao, H.

10.1101/2023.06.28.546888 — biochemistry — Posted on 2023-06-28

439 EVOLUTIONARY TRENDS IN SPECIES COMPLEX DIAGNOSED BY CYTOGENETIC POLYMORPHISM: THE CASE OF Hypostomus ancistroides (SILURIFORMES, LORICARIIDAE)

Rocha-Reis, D. A.; Brandao, K. d. O.; Dergam, J. A.; Pasa, R.; Kavalco, K. F.

10.1101/2020.09.22.308601 — evolutionary biology — Posted on 2023-06-28

440 Genomic and ecological factors shaping specialism and generalism across an entire subphylum

Opulente, D. A.; LaBella, A. L.; Harrison, M.-C.; Wolters, J. F.; Liu, C.; Li, Y.; Kominek, J.; Steenwyk, J. L.; Stoneman, H. R.; VanDenAvond, J.; Miller, C. R.; Langdon, Q. K.; Silva, M.; Goncalves, C.; Ubbelohde, E. J.; Li, Y.; Buh, K. V.; Jarzyna, M.; Haase, M. A. B.; Rosa, C. A.; Cadez, N.; Libkind, D.; DeVirgilio, J. H.; Hulfachor, A. B.; Kurtzman, C. P.; Sampaio, J. P.; Goncalves, P.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Rokas, A.; Hittinger, C. T.

10.1101/2023.06.19.545611 — evolutionary biology — Posted on 2023-06-28

441 Homologous chromosome recognition via nonspecific interactions

Marshall, W. F.; Fung, J. C.

10.1101/2023.06.09.544427 — cell biology — Posted on 2023-06-28

442 Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

Husser, M. C.; Pham, N. P.; Law, C.; Araujo, F. R. B.; Martin, V. J. J.; Piekny, A.

10.1101/2023.06.28.546942 — cell biology — Posted on 2023-06-28

443 Effects of destruxin A on the trehalose content, trehalase activity and their gene expression of Bemisia tabaci

Zhang, C.; Qiu, B.

10.1101/2023.06.28.546866 — molecular biology — Posted on 2023-06-28

444 Short 2'-O-methyl/LNA oligomers as highly-selective inhibitors of miRNA production in vitro and in vivo

Corradi, E.; Koralewska, N.; Milewski, M. C.; Masante, L.; Kierzek, R.; Figlerowicz, M.; Baudet, M.-L.; Kurzynska-Kokorniak, A.

10.1101/2023.06.28.546821 — molecular biology — Posted on 2023-06-28

445 Identifying molecular targets of a colloidal nanosilver formulation (Silversol) in multidrug resistant Pseudomonas aeruginosa

Gajera, G.; Thakkar, N.; Godse, C.; DeSouza, A.; Mehta, D.; Kothari, V.

10.1101/2023.06.27.546803 — microbiology — Posted on 2023-06-28

446 ORBIT for E. coli: Kilobase-scale oligonucleotide recombineering at high throughput and high efficiency

Saunders, S. H.; Ahmed, A. M.

10.1101/2023.06.28.546561 — microbiology — Posted on 2023-06-28

447 Identification of a novel and ancestral machinery involved in mitochondrial membrane branching in Trypanosoma brucei

Morel, C. A.; Asencio, C.; Blancard, C.; Salin, B.; Gontier, E.; Duvezin-Caubet, S.; Rojo, M.; Bringaud, F.; Tetaud, E.

10.1101/2023.06.28.546890 — microbiology — Posted on 2023-06-28

448 Deciphering Neuronal Deficit and Protein Profile Changes in Human Brain Organoids from Patients with Creatine Transporter Deficiency

Broca-Brisson, L.; Harati, R.; Disdier, C.; Mozner, O.; Gaston-Breton, R.; Maiza, A.; Costa, N.; Guyot, A.-C.; Sarkadi, B.; Apati, A.; Skelton, M.; Madrange, L.; Yates, F.; Armengaud, J.; Hamoudi, R. A.; Mabondzo, A.

10.1101/2023.06.01.543271 — neuroscience — Posted on 2023-06-28

449 Truly tiny acoustic biomolecules for ultrasound imaging and therapy

Ling, B.; Gungoren, B.; Yao, Y.; Dutka, P.; Smith, C. A. B.; Lee, J.; Swift, M. B.; Shapiro, M. G.

10.1101/2023.06.27.546773 — synthetic biology — Posted on 2023-06-28

450 Enabling AI in Synthetic Biology through Construction File Specification

Ataii, N.; Bakshi, S.; Chen, Y.; Fernandez, M.; Scheftel, Z.; Shao, Z.; Tou, C. J.; Vega, M.; Wang, Y.; Zhang, H.; Zhao, Z.; Anderson, J. C.

10.1101/2023.06.28.546630 — synthetic biology — Posted on 2023-06-28

451 Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

Lauer, S. M.-L.; Omar, M. H.; Golkowski, M. G.; Kenerson, H. L.; Pascual, B. C.; Forbush, K.; Smith, F. D.; Gordan, J.; Ong, S.-E. M.; Yeung, R. S.; Scott, J. D.

10.1101/2023.06.28.546958 — cancer biology — Posted on 2023-06-28

452 The positioning mechanics of microtubule asters in Drosophila embryo explants

de-Carvalho, J.; Tlili, S. L.; Saunders, T. E.; Telley, I. A.

10.1101/2023.03.31.535028 — biophysics — Posted on 2023-06-28

453 Distinct Conformations of Mirabegron Determined by MicroED

Lin, J.; Unge, J.; Gonen, T.

10.1101/2023.06.28.546957 — biochemistry — Posted on 2023-06-28

454 Crystal structures reveal nucleotide-induced conformational changes in G motifs and distal regions in guanylate-binding protein 2

Roy, S.; Wang, B.; Tian, Y.; Yin, Q.

10.1101/2023.06.28.546747 — biochemistry — Posted on 2023-06-28

455 A method for deep and quantitative protein profiling of urine sediment, soluble and exosome fractions for biomarker research

Pichler, P.; Kurnikowski, A.; Matzinger, M.; Mechtler, K.

10.1101/2023.06.26.546632 — biochemistry — Posted on 2023-06-28

456 Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures

Hu, J.; Xia, W.; Zeng, S.; Lim, Y.-J.; Tao, Y.; Sun, Y.; Zhao, L.; Wang, H.; Li, D.; Liu, C.; Li, Y.-M.

10.1101/2023.06.27.546682 — biochemistry — Posted on 2023-06-28

457 The interplay of DNA repair context with target sequence predictably biasses Cas9-generated mutations

Pallaseni, A.; Peets, E. M.; Girling, G.; Crepaldi, L.; Kuzmin, I.; Raudvere, U.; Peterson, H.; Sercin, O.; Mardin, B. R.; Kosicki, M.; Parts, L.

10.1101/2023.06.28.546891 — genetics — Posted on 2023-06-28

458 SparsePro: an efficient fine-mapping method integrating summary statistics and functional annotations

Zhang, W.; Najafabadi, H. S.; Li, Y.

10.1101/2021.10.04.463133 — genetics — Posted on 2023-06-28

459 Host adaptive radiation is associated with rapid virus diversification and cross-species transmission in African cichlid fishes

Costa, V. A.; Ronco, F.; Mifsud, J. C.; Harvey, E.; Salzburger, W.; Holmes, E. C.

10.1101/2023.06.28.546811 — evolutionary biology — Posted on 2023-06-28

460 Single-cell Transcriptomic Analysis of Salivary Gland Endothelial Cells

Altrieth, A. L.; Suarez, E.; Nelson, D. A.; Gabunia, S.; Larsen, M.

10.1101/2023.06.22.545817 — cell biology — Posted on 2023-06-28

461 Syntenin and CD63 Promote Exosome Biogenesis from the Plasma Membrane by Blocking Cargo Endocytosis

Ai, Y.; Guo, C.; Garcia-Contreras, M.; Sanchez, L. S.; Saftics, A.; Shodubi, O.; Raghunandan, S.; Xu, J.; Tsai, S.-J.; Dong, Y.; Li, R.; Jovanovic-Talisman, T.; Gould, S.

10.1101/2023.05.26.542409 — cell biology — Posted on 2023-06-28

462 Total cell N-glycosylation is altered during neuronal differentiation of iPSC to NSC and is disturbed by trisomy 21

Cindric, A.; Vuckovic, F.; Murray, A.; Klaric, T.; Alic, I.; Petrovic, D. J.; Kristic, J.; Nizetic, D.; Lauc, G.

10.1101/2023.06.28.546867 — molecular biology — Posted on 2023-06-28

463 Inter individual variability in neuronal expression of heat shock protein genes predicts stress survival in Caenorhabditis elegans.

Chauve, L.; Casanueva, M. O.; Vallejos, C. A.; Murdoch, S.; Todtenhaupt, P.

10.1101/2023.06.28.546835 — molecular biology — Posted on 2023-06-28

464 New insights into the helicase domain of human Dicer and its biochemical properties: ATPase and RNA rearrangement activities

Ciechanowska, K.; Szczepanska, A.; Szpotkowski, K.; Wojcik, K.; Urbanowicz, A.; Kurzynska-Kokorniak, A.

10.1101/2023.06.28.546842 — molecular biology — Posted on 2023-06-28

465 MicroRNA-Mediated Obstruction of Stem-loop Alternative Splicing (MIMOSAS): a global mechanism for the regulation of alternative splicing

Ruan, K.; Farinas Perez, G.; Liu, J.; Kubat, M.; Hofacker, I.; Wuchty, S.; Zhai, R. G.

10.1101/2023.04.14.536877 — molecular biology — Posted on 2023-06-28

466 Collagen prolyl 4-hydroxylases have sequence specificity towards different X-Pro-Gly triplets

Salo, A. M.; Rappu, P.; Koski, M. K.; Karjalainen, E.; Izzi, V.; Drushinin, K.; Miinalainen, I.; Käpylä, J.; Heino, J.; Myllyharju, J.

10.1101/2023.06.28.546674 — molecular biology — Posted on 2023-06-28

467 Evolution of resistance to a tricyclic pyrimidoindole DNA gyrase/topoisomerase inhibitor in Escherichia coli and Acinetobacter baumannii is driven by upregulation of efflux machinery

Leyn, S. A.; Kent, J. E.; Zlamal, J. E.; Elane, M.; Vercruysse, M.; Osterman, A. L.

10.1101/2023.06.26.546596 — microbiology — Posted on 2023-06-28

468 Serovar-level Identification of Bacterial Foodborne Pathogens From Full-length 16S rRNA Gene Sequencing

Grinevich, D.; Harden, L.; Grinevich, D. O.; Callahan, B. J.

10.1101/2023.06.28.546915 — microbiology — Posted on 2023-06-28

469 Characterization of a phyllosphere methylotroph community isolated with lanthanides

Govindaraju, A.; Friel, C. A.; Good, N. M.; Wayne, K. S.; Martinez-Gomez, N. C.

10.1101/2023.06.28.546956 — microbiology — Posted on 2023-06-28

470 Cryo-EM of cytoskeletal 'fibril' protein involved in Spiroplasma swimming

Sasajima, Y.; Kato, T.; Miyata, T.; Kiyama, H.; Kawamoto, A.; Makino, F.; Namba, K.; Miyata, M.

10.1101/2023.06.28.546849 — microbiology — Posted on 2023-06-28

471 The Salivary Microbiome and Predicted Metabolite Production are Associated with Progression from Barrett's Esophagus to Esophageal Adenocarcinoma

Solfisburg, Q. S.; Baldini, F.; Baldwin-Hunter, B. L.; Lee, H. H.; Park, H.; Freedberg, D. E.; Lightdale, C. J.; Korem, T.; Abrams, J. A.

10.1101/2023.06.27.546733 — microbiology — Posted on 2023-06-28

472 In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies

Sealover, N. E.; Theard, P. L.; Hughes, J. M.; Linke, A. J.; Daley, B. R.; Kortum, R. L.

10.1101/2023.01.27.525958 — cancer biology — Posted on 2023-06-28

473 Microtubule search-and-capture model evaluates the effect of chromosomal volume conservation on spindle assembly during mitosis

Nayak, P.; Chatterjee, S.; Paul, R.

10.1101/2023.04.08.536118 — biophysics — Posted on 2023-06-28

474 Cracking the black box of deep sequence-based protein-protein interaction prediction

Bernett, J.; Blumenthal, D. B.; List, M.

10.1101/2023.01.18.524543 — bioinformatics — Posted on 2023-06-28

475 Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

Diaz, R. E.; Ecker, A. K.; Correy, G. J.; Asthana, P.; Young, I. D.; Faust, B.; Thompson, M. C.; Seiple, I. B.; Van Dyken, S. J.; Locksley, R. M.; Fraser, J. S.

10.1101/2023.06.03.542675 — biochemistry — Posted on 2023-06-28

476 Concatenated tandem constructs of BK channels reveal three distinct types of subunit stoichiometry in channel modulation by the auxiliary γ subunit and mutations in the channel pore region

Chen, G.; Li, Q.; Yan, J.

10.1101/2023.06.26.546634 — biochemistry — Posted on 2023-06-28

477 Dopamine and norepinephrine differentially mediate the exploration-exploitation tradeoff

Chen, C. S.; Mueller, D.; Knep, E.; Ebitz, R. B.; Grissom, N. M.

10.1101/2023.01.09.523322 — animal behavior and cognition — Posted on 2023-06-28

478 Re-examining supposed correlations between synonymous codon usage and protein bond angles in E. coli

Akeju, O.; Cope, A. L.

10.1101/2022.10.26.513858 — evolutionary biology — Posted on 2023-06-28

479 Seasonality of host-seeking Ixodes ricinus nymph abundance in relation to climate

Hoch, T.; Madouasse, A.; Jacquot, M.; Wongnak, P.; Beugnet, F.; Bournez, L.; Huard, F.; Moutailler, S.; Plantard, O.; Poux, V.; Rene-Martellet, M.; Vayssier-Taussat, M.; Verheyden, H.; Vourc'h, G.; Chalvet-Monfray, K.; Agoulon, A.

10.1101/2022.07.25.501416 — ecology — Posted on 2023-06-28

480 Differential Inhibition of Intra- and Inter-molecular Protease Cleavages by Antiviral Compounds

Doherty, J. S.; Kirkegaard, K.

10.1101/2023.06.28.546904 — microbiology — Posted on 2023-06-28

481 Rat superior colliculus encodes the transition between static and dynamic vision modes

Gil, R.; Valente, M.; Shemesh, N.

10.1101/2022.11.27.518086 — neuroscience — Posted on 2023-06-28

482 Spatial Heterogeneity of Brain Lipids in SIV-infected Macaques Treated with Antiretroviral Therapy

White, C. J.; Gausepohl, A. M.; Wilkins, H. N.; Eberhard, C. D.; Orsburn, B. C.; Williams, D. W.

10.1101/2022.09.26.508302 — pathology — Posted on 2023-06-28

483 Reconstructing the evolutionary history of human, simian, and prosimian immunodeficiency viruses

Ghafari, M.; Simmonds, P.; Katzourakis, A.

10.1101/2023.06.28.546833 — evolutionary biology — Posted on 2023-06-28

484 Lymphocytic choriomeningitis arenavirus utilises tunnelling nanotube-like intercellular connections for cell-to-cell spread

Byford, O.; Shaw, A. B.; Tse, H. N.; Moon-Walker, A.; Saphire, E. O.; Whelan, S. P. J.; Stacey, M.; Hewson, R.; Fontana, J.; Barr, J. N.

10.1101/2023.06.28.546878 — microbiology — Posted on 2023-06-28

485 Unravelling Biosynthesis and Biodegradation Potentials of Microbial Dark Matters in Hypersaline Lakes

Qiu, Z.; Zhu, Y.; Zhang, Q.; Qiao, X.; Mu, R.; Xu, Z.; Yan, Y.; Wang, F.; Zhang, T.; Yu, K.

10.1101/2023.06.28.546814 — microbiology — Posted on 2023-06-28

486 12R-HETE acts as an endogenous ligand of Nur77 in intestine and regulates ILC3s plasticity

Huang, N. n.; Ye, L.; Li, H.; Wei, H. k.; Peng, J.

10.1101/2023.06.26.546623 — immunology — Posted on 2023-06-28

487 The circadian molecular clock in the suprachiasmatic nucleus is necessary but not sufficient for fear entrainment in the mouse

Bussi, I. L.; Ben-Hamo, M.; Leon, L. E. S.; Casiraghi, L. P.; Zhang, V. Y.; Neitz, A. F.; Lee, J.; Takahashi, J. S.; Kim, J. J.; de la Iglesia, H. O.

10.1101/2023.06.26.546624 — neuroscience — Posted on 2023-06-28

488 The brain's sensitivity to sensory error can be modulated by altering perceived variability

Tang, D.-l.; Parrell, B.; Beach, S.; Niziolek, C.

10.1101/2023.06.26.546615 — neuroscience — Posted on 2023-06-28

489 Application of Coincidence Index in the Discovery of Co-Expressed Metabolic Pathways

dos Santos, J. P. C.; Bruno, O.

10.1101/2023.06.26.546540 — systems biology — Posted on 2023-06-28

490 GEMspa: a Napari plugin for analysis of single particle tracking data

Keegan, S.; Fenyo, D.; Holt, L. J.

10.1101/2023.06.26.546612 — biophysics — Posted on 2023-06-28

491 Evolutionary potential of the monkeypox genome arising from interactions with human APOBEC3 enzymes

Delamonica, B.; Davalos, L.; Larijani, M.; Anthony, S.; Liu, J.; MacCarthy, T.

10.1101/2023.06.27.546779 — bioinformatics — Posted on 2023-06-28

492 SpheroScan: A User-Friendly Deep Learning Tool for Spheroid Image Analysis

Akshay, A.; Katoch, M.; Abedi, M.; Besic, M.; Shekarchizadeh, N.; Burkhard, F.; Bigger-Allen, A.; Adam, R.; Monastyrskaya, K.; Hashemi Gheinani, A.

10.1101/2023.06.28.533479 — bioinformatics — Posted on 2023-06-28

493 CHARR efficiently estimates contamination from DNA sequencing data

Lu, W.; Gauthier, L. D.; Poterba, T.; Giacopuzzi, E.; Goodrich, J. K.; Stevens, C. R.; King, D.; Daly, M. J.; Neale, B. M.; Karczewski, K. J.

10.1101/2023.06.28.545801 — bioinformatics — Posted on 2023-06-28

494 Enteropathway: the metabolic pathway database for the human gut microbiota

Shiroma, H.; Darzi, Y.; Terajima, E.; Nakagawa, Z.; Tsuchikura, H.; Tsukuda, N.; Moriya, Y.; Okuda, S.; Goto, S.; Yamada, T.

10.1101/2023.06.28.546710 — bioinformatics — Posted on 2023-06-28

495 New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

Giannelli, S. G.; Luoni, M.; Bellinazzi, B.; Iannielli, A.; Middeldorp, J.; Philippens, I.; Korbelin, J.; Broccoli, V.

10.1101/2023.06.27.546696 — bioengineering — Posted on 2023-06-28

496 Genetic Diversity Modulates The Physical And Transcriptomic Response Of Skeletal Muscle To Simulated Microgravity

Zeineddine, Y.; Friedman, M. A.; Buettmann, E. G.; Abraham, L. B.; Hoppock, G. A.; Donahue, H. J.

10.1101/2023.06.27.546810 — bioengineering — Posted on 2023-06-28

497 A human primary airway microphysiological system infected with SARS-CoV-2 distinguishes the treatment efficacy between nirmatrelvir and repurposed compounds fluvoxamine and amodiaquine

Lopez Quezada, L.; Mba Medie, F.; Gabriel, E. P.; Luu, R. J.; Rubio, L. D.; Mulhern, T. J.; Borenstein, J. T.; Fisher, C. R.; Gard, A. L.

10.1101/2023.06.27.546790 — bioengineering — Posted on 2023-06-28

498 RNA virome of sylvatic mosquitoes from northeast Brazil reveals a divergent and diverse insect-specific viral community

da Silva, A. F.; Machado, L. C.; da Silva, L. M. I.; Dezordi, F. Z.; Wallau, G. d. L.

10.1101/2023.06.27.546706 — genomics — Posted on 2023-06-28

499 Sequenced-based GWAS for linear classification traits in Belgian Blue beef cattle reveals new coding variants in genes regulating body size in mammals

Gualdron Duarte, J. L.; Yuan, C.; Gori, A.-S.; Costa Monteiro Moreira, G.; Takeda, H.; Coppieters, W.; Charlier, C.; Georges, M.; Druet, T.

10.1101/2023.06.27.546701 — genetics — Posted on 2023-06-28

500 The creation-mutation-selection model: the model and mathematical analysis

Irlam, G.

10.1101/2023.06.26.546616 — evolutionary biology — Posted on 2023-06-28

501 Identification of a recombinant human astrovirus type 5 strain from an acute gastroenteritis outbreak in Beijing, China

Mao, t.; Zhang, P.; Li, L.-l.; yang, m.; wang, y.; ma, y.; Li, D.-d.; li, j.; Duan, Z.-j.

10.1101/2023.06.27.546739 — evolutionary biology — Posted on 2023-06-28

502 GIFT an R package to access the Global Inventory of Floras and Traits

Denelle, P.; Weigelt, P.; Kreft, H.

10.1101/2023.06.27.546704 — ecology — Posted on 2023-06-28

503 Transcriptome based changes in expression of detoxification genes of Bemisia tabaci under destruxin A treatment

Zhang, C.; Guo, J.; Ali, S.; Qiu, B.-L.

10.1101/2023.06.28.545844 — molecular biology — Posted on 2023-06-28

504 Construction and Characterisation of a Structured, Tuneable, and Transparent 3D Culture Platform for Soil Bacteria

Rooney, L. M.; Dupuy, L. X.; Hoskisson, P. A.; McConnell, G.

10.1101/2023.06.28.546105 — microbiology — Posted on 2023-06-28

505 Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential

Martinez, D. R.; Moreira, F.; Zweigart, M. R.; Gully, K. L.; De la Cruz, G.; Brown, A.; Adams, L. E.; Catanzaro, N.; Yount, B.; Baric, T. J.; Mallory, M.; Conrad, H.; May, S. R.; Dong, S.; Scobey, T. D.; Montgomery, S.; Perry, J. K.; Babusis, D.; Barrett, K.; Nguyen, A.-H.; Nguyen, A.-Q.; Kalla, R.; Bannister, R.; Bilello, J.; Feng, J.; Cihlar, T.; Baric, R. S.; Mackman, R.; Schaefer, A.; Sheahan, T. P.

10.1101/2023.06.27.546784 — microbiology — Posted on 2023-06-28

506 Visual features are processed before navigational affordances in the human brain

Dwivedi, K.; Sadiya, S.; Balode, M. P.; Roig, G.; Cichy, R.

10.1101/2023.06.27.546695 — neuroscience — Posted on 2023-06-28

507 Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones

Ianevski, A.; Nader, K.; Bulava, D.; Giri, A. K.; Ruokoranta, T.; Kuusanmaki, H.; Ikonen, N.; Sergeev, P.; Vaha-Koskela, M.; Vaharautio, A.; Kontro, M.; Porkka, K.; Heckman, C. A.; Wennerberg, K.; Aittokallio, T.

10.1101/2023.06.26.546571 — bioinformatics — Posted on 2023-06-28

508 The evolution and mutational robustness of chromatin accessibility in Drosophila

Khodursky, S.; Zheng, E. B.; Svetec, N.; Durkin, S. M.; Benjamin, S.; Gadau, A.; Wu, X.; Zhao, L.

10.1101/2023.06.26.546587 — evolutionary biology — Posted on 2023-06-28

509 Piroplasm parasites (Apicomplexa: Piroplasmida) in northeastern populations of the invasive Asian longhorned tick, Haemaphysalis longicornis Neumann (Ixodida: Ixodidae), in the United States

Herb, H. E.; Ferreira, F. C.; Gonzalez, J.; Fonseca, D. M.

10.1101/2023.06.26.546593 — ecology — Posted on 2023-06-28

510 Recombinant outer membrane vesicles coupled with cytokines act as high-performance adjuvants against Helicobacter pylori infection in mice

Liu, Q.; Li, B.; Lu, J.; Zhang, Y.; Shang, Y.; Li, Y.; Gong, T.; Zhang, C.

10.1101/2023.06.26.546595 — immunology — Posted on 2023-06-28

511 SYNAPTOTAGMIN-9 IN MOUSE RETINA

Mesnard, C. S.; Hays, C. L.; Barta, C. L.; Gurumurthy, C.; Thoreson, W. B.

10.1101/2023.06.27.546758 — neuroscience — Posted on 2023-06-28

512 Molecular signature and functional properties of human pluripotent stem cell-derived brain pericytes

Bosworth, A.; Griffin, C.; Chakhoyan, A.; Sagare, A. P.; Nelson, A. R.; Wang, Y.; Kisler, K.; Montagne, A.; Clementel, V.; TCW, J.; Rust, R.; Coba, M.; Zlokovic, B.

10.1101/2023.06.26.546577 — neuroscience — Posted on 2023-06-28

513 SynBot: An open-source image analysis software for automated quantification of synapses

Savage, J. T.; Ramirez, J.; Risher, W. C.; Irala, D.; Eroglu, C.

10.1101/2023.06.26.546578 — neuroscience — Posted on 2023-06-28

514 Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activation.

Ghosh, S.; Isma, J.; Mazzeo, L.; Toniolo, A.; Simon, C.; Dotto, G.-P.

10.1101/2023.06.28.546870 — cancer biology — Posted on 2023-06-28

515 Zero-mode waveguide nanowells for single-molecule detection in living cells

Yang, S.; Klughammer, N.; Barth, A.; Tanenbaum, M. E.; Dekker, C.

10.1101/2023.06.26.546504 — biophysics — Posted on 2023-06-28

516 Orientation Single Molecule Localization Microscopy (oSMLM) for Decoding Orientation of Single Molecule

Joshi, P.; Mondal, P. P.

10.1101/2023.06.27.546198 — biophysics — Posted on 2023-06-28

517 Coarse-grained molecular dynamics simulations of lipid-protein interactions in SLC4 proteins

Zhekova, H. R.; Ramirez-Echemendia, D. P.; Sejdiu, B. I.; Pushkin, A.; Tieleman, D. P.; Kurtz, I.

10.1101/2023.06.26.546592 — biophysics — Posted on 2023-06-28

518 SpatialSPM: Statistical parametric mapping for the comparison of gene expression pattern images in multiple spatial transcriptomic datasets

Ohn, J.; Seo, M.-K.; Park, J.; Lee, D.; Choi, H.

10.1101/2023.06.26.546605 — bioinformatics — Posted on 2023-06-28

519 De Novo Generation and Prioritization of Target-Binding Peptide Motifs from Sequence Alone

Bhat, S.; Palepu, K.; Yudistyra, V.; Hong, L.; Kavirayuni, V. S.; Chen, T.; Zhao, L.; Wang, T.; Vincoff, S.; Chatterjee, P.

10.1101/2023.06.26.546591 — bioengineering — Posted on 2023-06-28

520 Cooperative control of a DNA origami force sensor

Robbins, A.; Hildebolt, H.; Neuhoff, M.; Beshay, P.; Winter, J. O.; Castro, C.; Bundschuh, R.; Poirier, M. G.

10.1101/2023.06.26.546608 — bioengineering — Posted on 2023-06-28

521 Engineering in vitro models of cystic fibrosis lung disease using neutrophil extracellular trap inspired biomaterials

Boboltz, A.; Yang, S.; Duncan, G.

10.1101/2023.06.26.546583 — bioengineering — Posted on 2023-06-28

522 Microglia produce the amyloidogenic ABri peptide in familial British dementia

Arber, C.; Casey, J. M.; Crawford, S.; Rambarack, N.; Yaman, U.; Wiethoff, S.; Augustin, E.; Piers, T. M.; Rostagno, A.; Ghiso, J.; Lewis, P. A.; Revesz, T.; Hardy, J.; Pocock, J. M.; Houlden, H.; Schott, J. M.; Salih, D. A.; Lashley, T.; Wray, S.

10.1101/2023.06.27.546552 — neuroscience — Posted on 2023-06-28

523 FISHtoFigure: An easy-to-use tool for rapid, multi-target partitioning and analysis of sub-cellular mRNA transcripts in smFISH data

Bentley-Abbot, C.; Heslop, R.; Pirillo, C.; Sinton, M. C.; Chandrasegaran, P. R. G.; McConnell, G.; Roberts, E.; Hutchinson, E.; MacLeod, A.

10.1101/2023.06.28.546871 — bioinformatics — Posted on 2023-06-28

524 Prestimulus neural variability affects behavioral performances mediated by poststimulus-evoked responses at the intraindividual and interindividual levels

Jiang, Z.; An, X.; Shuang Liu, S.; Yin, E.; Yan, Y.; Ming, D.

10.1101/2023.06.26.546352 — neuroscience — Posted on 2023-06-28

525 Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor

YANG, J.; Jablonowski, C. M.; Quarni, W.; Singh, S.; Tan, H.; Bostanthirige, D. H.; Jin, H.; Fang, J.; Chang, T.-C.; Finkelstein, D.; Cho, J.-H.; Hu, D.; Pagala, V.; Sakurada, S. M.; Pruett-Miller, S. M.; Wang, R.; Murphy, A.; Freeman, K.; Peng, J.; Davidoff, A.; Wu, G.

10.1101/2023.06.26.546606 — cancer biology — Posted on 2023-06-28

526 Vertical transmission of Borrelia turicatae (Spirochaetales: Borreliaceae) by autogenously reproducing Ornithodoros turicata (Ixodida: Argasidae) female naturally infected with the spirochetes

Filatov, S.; Krishnavajhala, A.; Lopez, J. E.

10.1101/2023.06.26.546580 — ecology — Posted on 2023-06-28

527 Intraspecific variation in the placement of campaniform sensilla on the wings of the hawkmoth Manduca sexta

Stanchak, K. E.; Deora, T.; Weber, A. I.; Hickner, M. K.; Moalin, A.; Abdalla, L.; Daniel, T. L.; Brunton, B. W.

10.1101/2023.06.26.546554 — neuroscience — Posted on 2023-06-28

528 Optogenetics reveals roles for supporting cells in force transmission to and from outer hair cells in the mouse cochlea

Lukashkina, V. A.; Levic, S.; Simoes, P. M.; Xu, Z.; Li, Y.; Haugen, T.; Zuo, J.; Lukashkin, A. N.; Russell, I. J.

10.1101/2023.06.26.546543 — neuroscience — Posted on 2023-06-28

529 Chemically-induced epileptic seizures in zebrafish: a systematic review

Chitolina, R.; Gallas-Lopes, M.; Reis, C. G.; Benvenutti, R.; Stahlhofer-Buss, T.; Calcagnotto, M. E.; Herrmann, A. P.; Piato, A.

10.1101/2023.06.26.546569 — neuroscience — Posted on 2023-06-28

530 A screen of alkaline and oxidative formulations for their inactivation efficacy of metal surface adsorbed prions using a steel-bead seed amplification assay

Heinzer, D.; Avar, M.; Pfammatter, M.; Moos, R.; Schwarz, P.; Buhmann, M.; Kuhn, B.; Mauerhofer, S.; Rosenberg, U.; Aguzzi, A.; Hornemann, S.

10.1101/2023.06.26.546570 — neuroscience — Posted on 2023-06-28

531 Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling

Hanssen, K. S.; Winter-Hjelm, N.; Niethammer, S. N.; Kobro-Flatmoen, A.; Witter, M. P.; Sandvig, A.; Sandvig, I.

10.1101/2023.06.26.546556 — neuroscience — Posted on 2023-06-28

532 Mixed structure- and sequence-based approach for protein graph neural networks with application to antibody developability prediction

Khade, P. M.; Maser, M.; Gligorijevic, V.; Watkins, A. M.

10.1101/2023.06.26.546331 — biophysics — Posted on 2023-06-28

533 Cracked actin filaments as mechanosensitive receptors

Zsolnay, V.; Gardel, M. L.; Kovar, D. R.; Voth, G. A.

10.1101/2023.06.26.546553 — biophysics — Posted on 2023-06-28

534 Establishment of a novel non-integrated human pluripotent stem cell-based gastruloid model

Yuan, G.; Wang, J.; Liu, Z.; Chen, M.; Zhu, P.; Zhang, H.; Hu, Z.; Cui, Y.; Yuan, Y.; Sha, J.

10.1101/2023.06.28.546720 — developmental biology — Posted on 2023-06-28

535 MORPHOGENIC VERSUS MITOGENIC ROLES OF SHH ARE SEGREGATED ON DISTINCT EXOSOMES REGULATED BY CELLULAR RAB7 LEVELS

Walvekar, A.; Pandey, S.; Kamat, S.; Damodar, S.; Ladher, R. K.; Vyas, N.

10.1101/2023.06.27.546648 — developmental biology — Posted on 2023-06-28

536 The Tubulin Nano-Code: a protofilament-specific pattern of tubulin post-translational modifications regulates ciliary beating mechanics

Alvarez Viar, G.; Klena, N.; Martino, F.; Nievergelt, A. P.; Pigino, G.

10.1101/2023.06.28.546853 — cell biology — Posted on 2023-06-28

537 p53 controls the nuclear entry and epigenetic modification of H3.1 by downregulating nuclear phosphatidic acid

Oikawa, T.; Hasegawa, J.; Ohnishi, N.; Onodera, Y.; Hashimoto, A.; Sasaki, J.; Sasaki, T.; Ueda, K.; Sabe, H.

10.1101/2023.06.27.545208 — cell biology — Posted on 2023-06-28

538 A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

Bedir, M.; Outwin, E.; Colnaghi, R.; Bassett, L.; Abramowicz, I.; O'Driscoll, M.

10.1101/2023.06.27.546694 — cell biology — Posted on 2023-06-28

539 Nuclear quality control of non-imported secretory proteins attenuates proteostasis decline in the cytosol

Banik, P.; Kamps, J.; Chen, Q.-Y.; Luesch, H.; Winklhofer, K. F.; Tatzelt, J.

10.1101/2023.06.27.546668 — cell biology — Posted on 2023-06-28

540 T-cell inflammation is prognostic of survival in patients with high-risk neuroblastoma enriched for an adrenergic signature

Kaufman, M. E.; Vayani, O. R.; Moore, K.; Chlenski, A.; Wu, T.; Chaves, G.; Lee, S. M.; Desai, A. V.; He, C.; Cohn, S. L.; Applebaum, M. A.

10.1101/2023.06.26.546541 — cancer biology — Posted on 2023-06-28

541 Synergistic effects of PARP inhibitors by Schlafen 11 and BRCA2-deficiency through accumulation of single-strand DNA gaps behind a fork

Onji, H.; Tate, S.; Sakaue, T.; Onishi, N.; Matsumoto, T.; Sugiyama, T.; Higashiyama, S.; Murai, J.

10.1101/2023.06.28.546820 — cancer biology — Posted on 2023-06-28

542 Hepatoblastoma exhibits a predominantly myeloid immune landscape and reveals opportunities for macrophage targeted immunotherapy

Krijgsman, D.; Kraaier, L.; Verdonschot, M.; Schubert, S.; Leusen, J.; Duiker, E.; de Kleine, R.; de Meijer, V.; de Krijger, R.; Zsiros, J.; Peng, W. C.; Vercoulen, Y.

10.1101/2023.06.28.546852 — cancer biology — Posted on 2023-06-28

543 Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling

Gregory, E.; Powers, I.; Jamshidi-Parsian, A.; Griffin, R. J.; Song, Y.

10.1101/2023.06.26.546629 — cancer biology — Posted on 2023-06-28

544 Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

Pillai, R.; LeBoeuf, S. E.; Hao, Y.; New, C.; Blum, J.; Rashidfarrokhi, A.; Huang, S. M.; Bahamon, C.; Wu, W. L.; Karadal-Ferrena, B.; Herrera, A.; Ivanova, E.; Cross, M.; Bossowski, J. P.; Ding, H.; Hayashi, M.; Rajalingam, S.; Karakousi, T.; Sayin, V. I.; Khanna, K. M.; Wong, K.-k.; Wild, R.; Tsirigos, A.; Poirier, J.; Rudin, C. M.; Davidson, S.; Koralov, S. B.; Papagiannakopoulos, T.

10.1101/2023.06.27.546750 — cancer biology — Posted on 2023-06-28

545 Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

Cannon, A. C.; Budagyan, K.; Uribe-Alvarez, C.; Kurimchak, A. M.; Araiza-Olivera, D.; Cai, K. Q.; Peri, S.; Zhou, Y.; Duncan, J. S.; Chernoff, J.

10.1101/2023.06.27.546707 — cancer biology — Posted on 2023-06-28

546 Tyramine and its AmTYR1 receptor modulate attention in honey bees (Apis mellifera)

Latshaw, J. S.; Mazade, R. E.; Petersen, M.; Mustard, J. A.; Sinakevitch, I.; Wissler, L.; Guo, X.; Cook, C. N.; Lei, H.; Gadau, J.; Smith, B. H.

10.1101/2022.09.02.506392 — animal behavior and cognition — Posted on 2023-06-28

547 Multifaceted effects on even-skipped transcriptional dynamics upon Kruppel dosage changes

Lin, S.; Lim, B.

10.1101/2023.06.27.546766 — developmental biology — Posted on 2023-06-28

548 Deep learning pipeline reveals key moments in human embryonic development predictive of live birth in IVF

Mapstone, C. A.; Hunter, H.; Brison, D.; Handl, J.; Plusa, B.

10.1101/2023.06.27.546684 — developmental biology — Posted on 2023-06-28

549 SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes

Ait-Si-Ali, S.; Granados, A.; Zamperoni, M.; Rapone, R.; Bouyioukos, C.; Del Maestro, L.; Joliot, V.; Albini, S.

10.1101/2023.06.28.546840 — cell biology — Posted on 2023-06-28

550 F-actin and Myosin F control apicoplast elongation dynamics which drive apicoplast-centrosome association in Toxoplasma gondii

Devarakonda, P. M.; Sarmiento, V.; Heaslip, A. T.

10.1101/2023.06.27.546809 — cell biology — Posted on 2023-06-28

551 Synthetic autotetraploid Caenorhabditis elegans resist severe cold stress by escaping cold induced death at the gravid adult stage.

Chauve, L.; McLysaght, A.; McGarry, A.; Butler, L.

10.1101/2023.06.28.546823 — cell biology — Posted on 2023-06-28

552 Self-extinguishing relay waves enable homeostaticcontrol of human neutrophil swarming

Strickland, J.; Pan, D.; Godfrey, C.; Kim, J. S.; Hopke, A.; Degrange, M.; Villavicencio, B.; Mansour, M. K.; Zerbe, C. S.; Irimia, D.; Amir, A.; Weiner, O. D.

10.1101/2023.06.27.546744 — cell biology — Posted on 2023-06-28

553 Identification of small molecule inhibitors of G3BP-driven stress granule formation

Freibaum, B. D.; Messing, J.; Nakamura, H.; Yurtsever, U.; Wu, J.; Kim, H. J.; Hixon, J.; Lemieux, R.; Duffner, J.; Huynh, W.; Wong, K.; White, M.; Lee, C.; Meyers, R.; Parker, R. D.; Taylor, J. P.

10.1101/2023.06.27.546770 — cell biology — Posted on 2023-06-28

554 Decline of DNA damage response along with myogenic differentiation

Sutcu, H.; Rassinoux, P.; Donnio, L.-M.; Neuillet, D.; Vianna, F.; Gabillot, O.; MARI, P.-O.; Baldeyron, C.; Giglia-Mari, G.

10.1101/2023.06.27.546688 — cell biology — Posted on 2023-06-28

555 Temporally dissociable mechanisms of spatial, feature, and motor selection during working memory-guided behavior

Ester, E.; Weese, R.

10.1101/2022.05.18.492385 — neuroscience — Posted on 2023-06-28

556 Nanoscale structural response of biomimetic cell membranes to controlled dehydration.

Krok, E.; Franquelim, H. G.; Chattopadhyay, M.; Orlikowska-Rzeznik, H.; Schwille, P.; Piatkowski, L.

10.1101/2023.06.26.546525 — biophysics — Posted on 2023-06-28

557 Design, Synthesis, Molecular Docking and Biological Activity of Pyrazolopyridines as Promising Lead Candidates Against Mycobacterium tuberculosis

H, S. P. R.; R, G.; Adigopula, L. N.; Muthukumaran, J.

10.1101/2023.06.26.546517 — bioinformatics — Posted on 2023-06-28

558 Transfemoral limb loss modestly increases the metabolic cost of optimal control simulations of walking

Miller, R. H.; Bell, E. M.; Russell Esposito, E.

10.1101/2023.06.26.546515 — bioengineering — Posted on 2023-06-28

559 A Deep Learning Approach for Modelling the Complex Relationship between Environmental Factors and Biological Features

Tripathi, D.; Basu, A.

10.1101/2023.06.26.546510 — genomics — Posted on 2023-06-28

560 EPIC-TRACE: predicting TCR binding to unseen epitopes using attention and contextualized embeddings

Korpela, D.; Jokinen, E.; Dumitrescu, A.; Huuhtanen, J.; Mustjoki, S.; Lähdesämki, H.

10.1101/2023.06.26.546489 — immunology — Posted on 2023-06-28

561 Proximity labelling and evolutionary evidence reveal insights into IL-1α nuclear networks and function

Wellens, R.; Tapia, V. S.; Bennett, H.; Adamson, A.; Rivers-Auty, J.; Green, J. P.; Lopez-Castejon, G.; Brough, D.; Hoyle, C.

10.1101/2023.06.26.546506 — immunology — Posted on 2023-06-28

562 Modulation by neuropeptides with overlapping targets results in functional overlap in oscillatory circuit activation

Cronin, E. M.; Schneider, A. C.; Nadim, F.; Bucher, D.

10.1101/2023.06.05.543756 — neuroscience — Posted on 2023-06-28

563 Proteomic profiling identifies Serpin B9 as mediator of resistance to CAR T-cell and bispecific antibody treatment in B-cell lymphoma

Brinkmann, B. J.; Capraz, T.; Roider, T.; Knoll, M.; Kolb, C.; Liu, Y.; Angeli-Terzidou, A.-E.; Paramasivam, N.; Eckstein, V.; Sauer, T.; Schmitt, M.; Rosenwald, A.; Mueller-Tidow, C.; Huber, W.; Dietrich, S.

10.1101/2023.06.26.546507 — cancer biology — Posted on 2023-06-28

564 Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

Wang, W.; Zhou, Y.; Wang, J.; Zhang, S.; Ozes, A.; Gao, H.; Fang, F.; Wang, Y.; Chu, X.; Liu, Y.; Wan, J.; Mitra, A. K.; O'Hagan, H. M.; Nephew, K. P.

10.1101/2023.06.26.546524 — cancer biology — Posted on 2023-06-28

565 Generation of Super-resolution Images from Barcode-based Spatial Transcriptomics Using Deep Image Prior

Park, J.; Cook, S.; Lee, D.; Choi, J.; Yoo, S.; Im, H.-J.; Lee, D.; Choi, H.

10.1101/2023.06.26.546529 — bioinformatics — Posted on 2023-06-28

566 Inference of Genomic Landscapes using Ordered Hidden Markov Models with Emission Densities (oHMMed)

Vogl, C.; Karapetiants, M.; Yildirim, B.; Kjartansdottir, H.; Kosiol, C.; Bergman, J.; Majka, M.; Mikula, L. C.

10.1101/2023.06.26.546495 — bioinformatics — Posted on 2023-06-28

567 nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome

Dagher, M.; Ongo, G.; Robichaud, N.; Kong, J.; Rho, W.; Teahulos, I.; Tavakoli, A.; Bovaird, S.; Merjaneh, S.; Tan, A.; Edwardson, K.; Scheepers, C.; Ng, A.; Hajjar, A.; Sow, B.; Vrouvides, M.; Lee, A.; DeCorwin-Martin, P.; Rasool, S.; Huang, J.; Han, Y.; Erps, T.; Coffin, S.; Chandrasekaran, S. N.; Miller, L.; Kost-Alimova, M.; Skepner, A.; Singh, S.; Carpenter, A. E.; Munzar, J.; Juncker, D.

10.1101/2023.04.17.535914 — bioengineering — Posted on 2023-06-28

568 Ghrelin is related to lower brain reward activation during touch

Pfabigan, D. M.; Frogner, E. R.; Schele, E.; Thorsby, P. M.; Dickson, S. L.; Sailer, U.

10.1101/2022.05.10.491384 — neuroscience — Posted on 2023-06-28

569 Modelling protein complexes with crosslinking mass spectrometry and deep learning

Stahl, K.; Brock, O.; Rappsilber, J.

10.1101/2023.06.07.544059 — bioinformatics — Posted on 2023-06-28

570 Stochastic characterization of navigation strategies in an automated variant of the Barnes maze

Lee, J.-Y.; Jung, D.; Royer, S.

10.1101/2023.04.14.536859 — animal behavior and cognition — Posted on 2023-06-28

571 Centriole elimination during C. elegans oogenesis initiates with loss of the central tube protein SAS-1

Pierron, M.; Woglar, A.; Busso, C.; Jha, K.; Mikeladze-Dvali, T.; Croisier, M.; Gönczy, P.

10.1101/2023.06.19.545600 — cell biology — Posted on 2023-06-28

572 Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq

Sunshine, S.; Puschnik, A. S.; Replogle, J. M.; Laurie, M. T.; Liu, J.; Zha, B. S.; Nunez, J. K.; Byrum, J. R.; McMorrow, A. H.; Frieman, M. B.; Winkler, J.; Qiu, X.; Rosenberg, O. S.; Leonetti, M. D.; Ye, C. J.; Weissman, J. S.; DeRisi, J. L.; Hein, M. Y.

10.1101/2022.07.15.500120 — systems biology — Posted on 2023-06-28

573 The GEF Cdc24 and GAP Rga2 synergistically regulate Cdc42 GTPase cycling

Tschirpke, S.; Daalman, W. K.-G.; Laan, L.

10.1101/2023.06.26.546500 — biochemistry — Posted on 2023-06-28

574 Microbial Associates of the Elm Leaf Beetle: Uncovering the Absence of Resident Bacteria and the Influence of Fungi on Insect Performance

Schott, J.; Rakei, J.; Remus-Emsermann, M. N.; Johnston, P. R.; Mbedi, S.; Sparmann, S.; Hilker, M.; Paniagua Voirol, L. R.

10.1101/2023.06.23.546294 — ecology — Posted on 2023-06-28

575 Regeneration leads to global tissue rejuvenation in aging sexual planarians

Dai, X.; Li, X.; Pletcher, S.; Paris, D.; Kruglyak, L.; Sobota, J.; Guo, L.

10.1101/2023.06.24.546358 — developmental biology — Posted on 2023-06-28

576 Is HDL-c plasma concentration a possible marker of HIV replication? A cross-sectional analysis in untreated HIV-infected individuals accessing HIV care in Italy

Piconi, S.; Bottanelli, M.; Marchetti, G.; Gori, A.; Castagna, A.; Cicalini, S.; Squillace, N.; Cozzi Lepri, A.; Orofino, G.; Ceccherini Silbertein, F.; Di Biagio, A.; D'Arminio Monforte, A.

10.1101/2023.06.23.546265 — immunology — Posted on 2023-06-28

577 50-nm gas-filled protein nanostructures to enable the access of lymphatic cells by ultrasound technologies

Shen, Q.; Li, Z.; Meyer, M. D.; De Guzman, M. T.; Lim, J. C.; Bouchard, R. R.; Lu, G. J.

10.1101/2023.06.27.546433 — synthetic biology — Posted on 2023-06-28

578 SHARK enables homology assessment in unalignable anddisordered sequences

Chow, C. F. W.; Ghosh, S.; Hadarovich, A.; Toth-Petroczy, A.

10.1101/2023.06.26.546490 — bioinformatics — Posted on 2023-06-28

579 Reference genome of the bicolored carpenter ant, Camponotus vicinus

Ward, P. S.; Cash, E. I.; Ferger, K.; Escalona, M.; Sahasrabudhe, R.; Miller, C.; Toffelmier, E.; Fairbairn, C.; Seligmann, W.; Shaffer, H. B.; Tsutsui, N. D.

10.1101/2023.06.26.546281 — genomics — Posted on 2023-06-28

580 Variations in Homoeologous Dosage and Epigenomics Mark the Early Evolution of Synthetic Brassica Tetraploids

Zhang, K.; Yang, Y.; Zhang, L.; Cui, Y.; Wu, J.; Liang, J.; Li, X.; Zhang, L.; Zhang, X.; Zhang, Y.; Guo, Z.; Chen, S.; Freeling, M.; Wang, X.; Cheng, F.

10.1101/2023.06.27.543697 — genomics — Posted on 2023-06-28

581 Beyond venomous fangs: Uloboridae spiders have lost their venom apparatus but not their toxins

Peng, X.; Dederichs, T.; Lüddecke, T.; Michalik, P.; Mucciolo, A.; Robinson-Rechavi, M.; Zancolli, G.

10.1101/2023.06.26.546488 — evolutionary biology — Posted on 2023-06-28

582 The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution

Eleftheriadi, K.; Guiglielmoni, N.; Salces-Ortiz, J.; Vargas-Chavez, C.; Gut, M.; Flot, J.-F.; Schmidt-Rhaesa, A.; Fernandez, R.

10.1101/2023.06.26.546503 — evolutionary biology — Posted on 2023-06-28

583 Make Like a Tree and Leave: How Will Tree Species Loss and Climate Change Alter Future Temperate Broadleaved Forests?

West, B.; Jones, D. L.; Robinson, E.; Keith, A.; Kallow, S.; Marrs, R.; Smart, S. M.

10.1101/2023.06.26.546609 — ecology — Posted on 2023-06-28

584 Data-driven discovery of innate immunomodulators via machine learning-guided high throughput screening

Tang, Y.; Kim, J. Y.; IP, C. K.; Bahmani, A.; Chen, Q.; Rosenberger, M. G.; Esser-Kahn, A. P.; Ferguson, A. L.

10.1101/2023.06.26.546393 — immunology — Posted on 2023-06-28

585 The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in colon cancer cells

Slaninova, V.; Heron-Milhavet, L.; Robin, M.; Jeanson, L.; Kantar, D.; Tosi, D.; Berhelin, L.; Gongora, C.; Djiane, A.

10.1101/2023.03.17.533075 — cancer biology — Posted on 2023-06-28

586 Effects of microplastics mixed with natural particles on Daphnia magna populations

Schuer, C.; Beck, J.; Lambert, S.; Scherer, C.; Oehlmann, J.; Wagner, M.

10.1101/2022.05.04.490562 — ecology — Posted on 2023-06-28

587 Quantifying and correcting estimation bias in transcriptional parameter inference from single-cell data

Grima, R.; Esmenjaud, P.-M.

10.1101/2023.06.19.545536 — systems biology — Posted on 2023-06-28

588 Cytotoxic Activity Of A New Isoform L-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom In Human Leukemic HL60 Cells

Heleno, M. A. G.; Suni-Curasi, D. L.; Vilca-Quispe, J.; Ponce-Fuentes, E. A.; Obando-Pereda, G.; Carvalho, J. E.; Nowill, A.; Ponce-Soto, L. A.

10.1101/2020.01.15.907758 — pharmacology and toxicology — Posted on 2023-06-28

589 Single-Molecule Super-Resolution Microscopy Reveals Formation of NS2B3 Protein Clusters on Mitochondrial Network Leading to its Fragmentation during the Onset of Dengue (Denv-2) Viral Infection

Varghese, J. M.; Joshi, P.; S, A.; Mondal, P. P.

10.1101/2022.12.18.520514 — pathology — Posted on 2023-06-28

590 E2F1 methylation by SETD6 regulates SETD6 expression via positive feedback mechanism

Kublanovsky, M.; Ulu, G.; Weirich, S.; Levy, N.; Feldman, M.; Jeltsch, A.; Levy, D.

10.1101/2023.06.27.546651 — molecular biology — Posted on 2023-06-27

591 Uncovering a stability signature of brain dynamics associated with meditation experience using massive time-series feature extraction

Bailey, N. W.; Fulcher, B. D.; Caldwell, B.; Hill, A. T.; Fitzgibbon, B.; van Dijk, H.; Fitzgerald, P. B.

10.1101/2023.06.23.546355 — neuroscience — Posted on 2023-06-28

592 Germline-encoded specificities and the predictability of the B cell response

Vieira, M. C.; Palm, A.-K. E.; Stamper, C. T.; Tepora, M. E.; Nguyen, K. D.; Pham, T. D.; Boyd, S. D.; Wilson, P. C.; Cobey, S.

10.1101/2022.09.16.508315 — immunology — Posted on 2023-06-27

593 Cl--dependent amplification of excitatory synaptic potentials at distal dendrites revealed by voltage imaging

Morita, M.; Higashi, R.; Kawaguchi, S.-y.

10.1101/2023.05.29.542696 — neuroscience — Posted on 2023-06-27

594 Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IkappaBalpha without requiring ATP

Borar, P.; Biswas, T.; Huxford, T.; Ghosh, G.; Polley, S.

10.1101/2023.06.27.546692 — biochemistry — Posted on 2023-06-27

595 Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization

Guo, T.; Sperber, A. M.; Krieger, I. V.; Duan, Y.; Chemelewski, V. R.; Sacchettini, J. C.; Herman, J. K.

10.1101/2023.06.26.546597 — microbiology — Posted on 2023-06-27

596 Global diversity and inferred ecophysiology of microorganisms with the potential for dissimilatory sulfate/sulfite reduction

Diao, M.; Dyksma, S.; Koeksoy, E.; Ngugi, D. K.; Anantharaman, K.; Loy, A.; Pester, M.

10.1101/2023.06.27.546762 — microbiology — Posted on 2023-06-27

597 No sex differences in oxygen uptake or extraction kinetics in the moderate or heavy exercise intensity domains

Solleiro Pons, M.; Bernert, L.; Hume, E.; Hughes, L.; Williams, Z.; Burnley, M.; Ansdell, P.

10.1101/2023.06.26.546455 — physiology — Posted on 2023-06-27

598 Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IkappaBalpha without requiring ATP

Polley, S.; Borar, P.; Biswas, T.; Huxford, T.; Ghosh, G.

10.1101/2023.06.27.546692 — biochemistry — Posted on 2023-06-27

599 Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain

Ramani, B.; Rose, I. V. L.; Pan, A.; Tian, R.; Ma, K.; Palop, J. J.; Kampmann, M.

10.1101/2023.06.13.544831 — genomics — Posted on 2023-06-27

600 Loss Of Chromodomain of Male-Specific Lethal 3 (MSL3) Does Not Affect Spermatogenesis In Rodents

Mitchell, T.; Lin, J. M.; James, J. R.; Hicks, S. M.; Rangan, P.; Forni, P. E.

10.1101/2023.03.16.532933 — developmental biology — Posted on 2023-06-27

601 Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone localization and sliding force

Gergely, Z.; Jones, M. H.; Zhou, B.; Cash, C.; McIntosh, R.; Betterton, M.

10.1101/2023.05.01.538972 — cell biology — Posted on 2023-06-27

602 LPCAT2 Regulates CD14 Expression During Macrophage Inflammatory Response to E. coli O111:B4.

Poloamina, V. I.; Abate, W.; Fejer, G.; Jackson, S. K.

10.1101/2023.06.27.546434 — molecular biology — Posted on 2023-06-27

603 E2F1 methylation by SETD6 regulates SETD6 expression via positive feedback mechanism

Levy, D.; Kublanovsky, M.; Ulu, G.; Weirich, S.; Levy, N.; Feldman, M.; Jeltsch, A.

10.1101/2023.06.27.546651 — molecular biology — Posted on 2023-06-27

604 Homing in on the rare virosphere reveals the native host of giant viruses

Fromm, A.; Hevroni, G.; Vincent, F.; Schatz, D.; Martinez-Gutierrez, C. A.; Aylward, F. O.; Vardi, A.

10.1101/2023.06.27.546645 — microbiology — Posted on 2023-06-27

605 C. difficile may be overdiagnosed in adults and is a prevalent commensal in infants

Ferretti, P.; Wirbel, J.; Maistrenko, O. M.; Van Rossum, T.; Alves, R.; Fullam, A.; Akanni, W.; Schudoma, C.; Schwarz, A.; Thielemann, R.; Thomas, L.; Kandels, S.; Hercog, R.; Telzerow, A.; Letunic, I.; Kuhn, M.; Zeller, G.; Schmidt, T. S.; Bork, P.

10.1101/2022.02.16.480740 — microbiology — Posted on 2023-06-27

606 The Sde phosphoribosyl-linked ubiquitin transferases exploit reticulons to protect the integrity of the Legionella-containing vacuole

Zhang, M.; Kim, S.; Isberg, R. R.

10.1101/2023.06.27.546723 — microbiology — Posted on 2023-06-27

607 Evolution of resistance to a tricyclic pyrimidoindole DNA gyrase/topoisomerase inhibitor in Escherichia coli and Acinetobacter baumannii is driven by upregulation of efflux machinery

Leyn, S. A.; Kent, J. E.; Zlamal, J. E.; Elane, M.; Vercruysse, M.; Osterman, A. L.

10.1101/2023.06.26.546596 — microbiology — Posted on 2023-06-27

608 The use of plant extracts and bacteriophages as an alternative therapy approach in combating bacterial infections: the study of lytic phages and Stevia rebaudiana

Stachurska, X.; Mizielinska, M.; Ordon, M.; Nawrotek, P.

10.1101/2023.06.27.546765 — microbiology — Posted on 2023-06-27

609 The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system

Edwards, A. N.; McBride, S. M.

10.1101/2023.06.26.546640 — microbiology — Posted on 2023-06-27

610 Label-free analysis of bacterial growth and lysis at the single-cell level using droplet microfluidics and object detection-oriented deep learning

Tiwari, A.; Nikolic, N.; Anagnostidis, V.; Gielen, F.

10.1101/2023.06.27.546533 — microbiology — Posted on 2023-06-27

611 Cell cycle-dependent organization of a bacterial centromere through multi-layered regulation of the ParABS system

Kaljevic, J.; Le, T. B. K.; Laloux, G.

10.1101/2023.06.27.546657 — microbiology — Posted on 2023-06-27

612 Antiviral Type III CRISPR signalling via conjugation of ATP and AdoMet

Chi, H.; Hoikkala, V.; Gruschow, S.; Graham, S.; Shirran, S.; White, M. F.

10.1101/2023.06.26.546636 — microbiology — Posted on 2023-06-27

613 Deciphering the rule of antigen-antibody amino acid interaction

Jiang, M.; Fang, C.; MA, Y.

10.1101/2023.05.05.539546 — immunology — Posted on 2023-06-27

614 Cognitive Dynamics Estimation: A whole-brain spatial regression paradigm for extracting the temporal dynamics of cognitive processes

Koyama, Y.; Yamamoto, T.; Hirayama, J.-i.; Jimura, K.; Sadato, N.; Chikazoe, J.

10.1101/2023.06.12.543130 — neuroscience — Posted on 2023-06-27

615 The locus of recognition memory signals in human cortex depends on the complexity of the memory representations

Sanders, D. M. W.; Cowell, R. A.

10.1101/2021.06.15.448519 — neuroscience — Posted on 2023-06-27

616 Listening with generative models

Cusimano, M.; Hewitt, L. B.; McDermott, J. H.

10.1101/2023.04.27.538626 — neuroscience — Posted on 2023-06-27

617 Delayed primacy recall performance predicts post mortem Alzheimers disease pathology from unimpaired ante mortem cognitive baseline

Bruno, D.; Gicas, K.; Jauregi Zinkunegi, A.; Mueller, K. D.; Lamar, M.

10.1101/2023.06.26.546225 — neuroscience — Posted on 2023-06-27

618 Dynamics of the epigenetic landscape during development and in response to drought stress in sorghum

Hu, Y.; He, C.; Shen, Y.; Zeng, G.; Bi, S.; Huang, Q.; Qin, X.; Deng, Z.; He, Z.; Shen, X.

10.1101/2023.04.24.537601 — plant biology — Posted on 2023-06-27

619 Photosynthetic acclimation mediates exponential growth of a desert plant in Death Valley summer

Prado, K.; Xue, B.; Johnson, J. E.; Field, S.; Stata, M.; Hawkins, C. L.; Hsia, R.-C.; Liu, H.; Cheng, S.; Rhee, S. Y.

10.1101/2023.06.23.546155 — plant biology — Posted on 2023-06-27

620 NMFClustering: Accessible NMF-based clustering utilizing GPU acceleration

Liefeld, T.; Huang, E.; Wenzel, A. T.; Yoshimoto, K.; Sharma, A. K.; Sicklick, J. K.; Mesirov, J. P.; Reich, M. M.

10.1101/2023.06.16.545370 — bioinformatics — Posted on 2023-06-27

621 Combiroc: when 'less is more' in bulk and single cell marker signatures.

Ferrari, I.; Mazzara, S.; Crosti, M.; Grifantini, R.; Abrignani, S.; Bombaci, M.; Rossi, R. L.

10.1101/2022.01.17.476603 — bioinformatics — Posted on 2023-06-27

622 Glycoprofiling of proteins as prostate cancer biomarkers: a multinational population study

Tkac, J.; Pinkeova, A.; Tomikova, A.; Bertokova, A.; Fabinyova, E.; Bartova, R.; Jane, E.; Hroncekova, S.; Sievert, K.-D.; Sokol, R.; Jirasko, M.; Kucera, R.; Eder, I. E.; Horninger, W.; Klocker, H.; Dubjakova, P.; Fillo, J.; Bertok, T.

10.1101/2023.06.27.546717 — biochemistry — Posted on 2023-06-27

623 Homocysteine Metabolites Impair the Phf8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of PHF8-targeting miR-22-3p and miR-1229-3p in Human Vascular Endothelial Cells

Witucki, L.; Jakubowski, H.

10.1101/2023.06.27.546759 — biochemistry — Posted on 2023-06-27

624 Using energy to go downhill - a genoprotective role for ATPase activity in DNA topoisomerase II

Bandak, A. F.; Blower, T. R.; Nitiss, K. c.; Shah, V.; Nitiss, J. L.; Berger, J. M.

10.1101/2023.06.27.546777 — biochemistry — Posted on 2023-06-27

625 An engineered biosensor enables dynamic aspartate measurements in living cells

Davidsen, K.; Marvin, J. S.; Aggarwal, A.; Brown, T. A.; Sullivan, L. B.

10.1101/2023.06.27.546775 — biochemistry — Posted on 2023-06-27

626 Acyl-CoA thioesterase-2 facilitates beta-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner

Bekeova, C.; Han, J. I.; Xu, H.; Kerr, E.; Blackburne, B.; Lynch, S. C.; Mesaros, C.; Murgia, M.; Vadigepalli, R.; Beld, J.; Leonardi, R.; Snyder, N. W.; Seifert, E. L.

10.1101/2023.06.27.546724 — biochemistry — Posted on 2023-06-27

627 Nine-residue low-complexity disordered peptide as a model system, an NMR/CD study

Vugmeyster, L.; Rodgers, A.; Gwin, K.; Ostrovsky, D.; Smirnov, S. L.

10.1101/2023.02.16.528870 — biochemistry — Posted on 2023-06-27

628 Lysine vitcylation is a novel vitamin C-derived protein modification that enhances STAT1-mediated immune response

He, X.; Wei, Y.; Wu, J.; Wang, Q.; Bergholz, J. S.; Gu, H.; Zou, J.; Lin, S.; Wang, W.; Xie, S.; Jiang, T.; Lee, J.; Asara, J. M.; Zhang, K.; Cantley, L. C.; Zhao, J. J.

10.1101/2023.06.27.546774 — biochemistry — Posted on 2023-06-27

629 The mechanism of Atg15-mediated membrane disruption in autophagy

Kagohashi, Y.; Sasaki, M.; May, A. I.; Kawamata, T.; Ohsumi, Y.

10.1101/2023.06.26.546516 — biochemistry — Posted on 2023-06-27

630 Field phenomics reveals genetic variation for transpiration response to vapor pressure deficit in sorghum

Raymundo, R.; Wang, X.; Felderhoff, T.; Sexton-Bowser, S.; Poland, J.; Lipka, A.; Morris, G. P.

10.1101/2023.06.23.546345 — genetics — Posted on 2023-06-27

631 Severe fire regimes select for highly resilient populations in ectotherms

Sousa, H. C.; Malvasio, A.; Colli, G. R.; Salguero-Gomez, R. C.

10.1101/2023.06.25.546448 — ecology — Posted on 2023-06-27

632 Structural and dynamical basis for the interaction of HSP70-EEVD with JDP Sis1

Matos, C. O.; Pinheiro, G. M. S.; Caruso, I. P.; Amorim, G. C.; Almeida, F. C. L.; Ramos, C. H. I.

10.1101/2022.11.26.517237 — molecular biology — Posted on 2023-06-27

633 Influence of DNA extraction methods on microbiome and resistome analysis in activated sludge

Calderon-Franco, D.; Kok, D.; Dukker, R.; Abbas, B.; Abreu-Silva, J.; Rocha, J.; Lopez Marin, M. A.; Pallares-Vega, R.; Gajdos, S.; Ananth, M.; Apoorva, S.; Karpisek, I.; Solcova, M.; Hernandez-Leal, L.; Bartacek, J.; Manaia, C.; Purkrtova, S.; Weissbrodt, D. G.

10.1101/2023.06.26.546617 — molecular biology — Posted on 2023-06-27

634 Prevalence of pathogenic bacteria detected by qPCR from cultured Nile tilapia (Oreochromis niloticus Linnaeus, 1758) in southwest Mexico

Soto-Rodriguez, S. A.; Lopez, F. I. M.; Rendon, K. G. A.

10.1101/2023.06.27.546743 — microbiology — Posted on 2023-06-27

635 Eukaryotic antiviral immune proteins arose via convergence, horizontal transfer, and ancient inheritance

Culbertson, E. M.; Levin, T. C.

10.1101/2023.06.27.546753 — microbiology — Posted on 2023-06-27

636 Loss of Bacteroides thetaiotaomicron bile acid altering enzymes impact bacterial fitness and the global metabolic transcriptome

McMillan, A. S.; Foley, M. H.; Perkins, C. E.; Theriot, C. M.

10.1101/2023.06.27.546749 — microbiology — Posted on 2023-06-27

637 Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis

Brogan, A. P.; Habib, C.; Hobbs, S. J.; Kranzusch, P. J.; Rudner, D. Z.

10.1101/2023.06.27.546760 — microbiology — Posted on 2023-06-27

638 Divergent hepaciviruses, chuvirus and deltaviruses in Australian marsupial carnivores (Dasyurids) identified through transcriptome mining

Harvey, E.; Mifsud, J. C.; Holmes, E. C.; Mahar, J. E.

10.1101/2023.06.27.546737 — microbiology — Posted on 2023-06-27

639 Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum

Xu, R.; Beatty, W.; Greigert, V.; Witola, W. H.; Sibley, L. D.

10.1101/2023.06.27.546703 — microbiology — Posted on 2023-06-27

640 Functional loss of rffG and rfbB, encoding dTDP-glucose 4,6-dehydratase, changes colony morphology, cell shape, motility and virulence in Salmonella Typhimurium

Chakravorty, S.; Banerjee, P.; Joseph, J. P.; Pathak, S.; Verma, T.; Das, M.; Nandi, D.

10.1101/2023.06.27.546680 — microbiology — Posted on 2023-06-27

641 A human urothelial microtissue model reveals shared colonization and survival strategies between uropathogens and asymptomatic bacteria

Flores, C.; Ling, J.; Loh, A.; Maset, R. G.; Aw, A.; White, I. J.; Fernando, R.; Rohn, J. L.

10.1101/2023.06.27.543376 — microbiology — Posted on 2023-06-27

642 Deciphering the role of the OmpC-Mla system in bile salt resistance

Zhu, F.; Chong, Z.-S.; Chng, S.-S.

10.1101/2023.06.27.546672 — microbiology — Posted on 2023-06-27

643 Foveated metamers of the early visual system

Broderick, W. F.; Rufo, G.; Winawer, J.; Simoncelli, E.

10.1101/2023.05.18.541306 — neuroscience — Posted on 2023-06-27

644 High-performing neural network models of visual cortex benefit from high latent dimensionality

Elmoznino, E.; Bonner, M. F.

10.1101/2022.07.13.499969 — neuroscience — Posted on 2023-06-27

645 A reference-unbiased super-pangenome of the North American wild grape species (Vitis spp.) reveals genus-wide association with adaptive traits

Cochetel, N.; Minio, A.; Guarracino, A.; Garcia, J. F.; Figueroa-Balderas, R.; Massonnet, M.; Londo, J.; Garrison, E.; Gaut, B.; Cantu, D.

10.1101/2023.06.27.545624 — genomics — Posted on 2023-06-27

646 Lymphocytic choriomeningitis arenavirus requires cellular COPI and AP-4 complexes for efficient replication and virion production.

Byford, O.; Shaw, A. B.; Tse, H. N.; Todd, E. J. A. A.; Alvarez-Rodriguez, B.; Hewson, R.; Fontana, J.; Barr, J. N.

10.1101/2023.06.27.546563 — microbiology — Posted on 2023-06-27

647 A consensus cell type atlas from multiple connectomes reveals principles of circuit stereotypy and variation

Schlegel, P.; Yin, Y.; Bates, A. S.; Dorkenwald, S.; Eichler, K.; Brooks, P.; Han, D. S.; Gkantia, M.; dos Santos, M.; Munnelly, E. J.; Badalamente, G.; Capdevila, L. S.; Sane, V. A.; Pleijzier, M. W.; Tamimi, I. F. M.; Dunne, C. R.; Salgarella, I.; Javier, A.; Fang, S.; Perlman, E.; Kazimiers, T.; Jagannathan, S. R.; Matsliah, A.; Sterling, A. R.; Yu, S.-c.; McKellar, C. E.; FlyWire Consortium, ; Costa, M.; Seung, H. S.; Murthy, M.; Hartenstein, V.; Bock, D. D.; Jefferis, G. S. X. E.

10.1101/2023.06.27.546055 — neuroscience — Posted on 2023-06-27

648 Population encoding of stimulus features along the visual hierarchy

Dyballa, L.; Rudzite, A. M.; Hoseini, M. S.; Thapa, M.; Stryker, M. P.; Field, G. D.; Zucker, S. W.

10.1101/2023.06.27.545450 — neuroscience — Posted on 2023-06-27

649 DENetwork: Unveiling Regulatory and Signaling Networks Behind Differentially-Expressed Genes

Su, T.-Y.; Islam, Q. S.; Huang, S. K.; Baglole, C. J.; Ding, J.

10.1101/2023.06.27.546719 — bioinformatics — Posted on 2023-06-27

650 Metabolic-Pathway-Presence-Heatmap (MPPH):Constructing phylogenetic trees based on metabolic pathways.

Du, Y.-H.; Mu, J.-H.

10.1101/2023.06.27.546232 — bioinformatics — Posted on 2023-06-27

651 MGSurvE: A framework to optimize trap placement for genetic surveillance of mosquito population

Sanchez Castellanos, H. M.; Smith, D. L.; Marshall, J. M.

10.1101/2023.06.26.546301 — bioinformatics — Posted on 2023-06-27

652 Photoacoustic Imaging as a Novel Non-Invasive Biomarker to Assess Intestinal Tissue Oxygenation and Motility in Neonatal Rats

Weis, V. G.; Cruz-Diaz, N.; Rauh, J. L.; Ellison, M. A.; Yamaleyeva, L. M.; Welch, C. D.; Zeller, K. A.; Weis, J. A.

10.1101/2023.06.27.545971 — bioengineering — Posted on 2023-06-27

653 Decreased efficacy of a COVID-19 vaccine due to mutations present in early SARS-CoV-2 variants of concern

Weidenbacher, P. A.; Friedland, N.; Sanyal, M.; Morris, M. K.; Do, J.; Hanson, C.; Kim, P. S.

10.1101/2023.06.27.546764 — biochemistry — Posted on 2023-06-27

654 Uncovering Ghost Introgression Through Genomic Analysis of a Distinct East Asian Hickory Species

Zhang, W.-P.; Ding, Y.-M.; Cao, Y.; Li, P.; Yang, Y.; Pang, X.-X.; Bai, W.-N.; Zhang, D.-Y.

10.1101/2023.06.26.546421 — evolutionary biology — Posted on 2023-06-27

655 Paridiprubart inhibits TLR4-dependant NF-κB activation by multiple pathogens

Malty, R.; Hilbe, R.; Ahn, S.; Kesselman, L.; Lam, J.; Kasawara, K.; Costa, L.; Rajakulendran, N.; Gordon, B.; Brooks, M.; Mubareka, S.; Tancevski, I.; Gray-Owen, S. D.

10.1101/2023.06.27.545921 — immunology — Posted on 2023-06-27

656 Focusing antibody responses to the fusion peptide in rhesusmacaques

Cottrell, C. A.; Pratap, P. P.; Cirelli, K. M.; Carnathan, D. G.; Enemuo, C. A.; Antansijevic, A.; Ozorowski, G.; Sewall, L. M.; Gao, H.; Greene, K. M.; Allen, J. D.; Ngo, J. T.; Choe, Y.; Nogal, B.; Silva, M.; Bhiman, J.; Pauthner, M. G.; Irvine, D. J.; Montefiori, D.; Crispin, M.; Burton, D. R.; Silvestri, G.; Crotty, S.; Ward, A. B.

10.1101/2023.06.26.545779 — immunology — Posted on 2023-06-27

657 The role of binocular disparity in the neural representation of multiple moving stimuli in the visual cortex

Chakrala, A. S.; Xiao, J.; Huang, X.

10.1101/2023.06.25.546480 — neuroscience — Posted on 2023-06-27

658 Screening of leaf extraction and storage conditions for eco-metabolomics studies

Lang, J.; Ramos, S. E.; Smohunova, M.; Bigler, L.; Schuman, M. C.

10.1101/2023.06.26.546251 — plant biology — Posted on 2023-06-27

659 MAPS: Pathologist-level cell type annotation from tissue images through machine learning

Shaban, M.; Bai, Y.; Qiu, H.; Mao, S.; Yeung, J.; Yeo, Y. Y.; Shanmugam, V.; Shanmugam, V.; Chen, H.; Zhu, B.; Nolan, G. P.; Shipp, M. A.; Rodig, S. J.; Jiang, S.; Mahmood, F.

10.1101/2023.06.25.546474 — cancer biology — Posted on 2023-06-27

660 Implicit model to capture electrostatic features of membrane environment.

Samanta, R.; Gray, J. J.

10.1101/2023.06.26.546486 — biophysics — Posted on 2023-06-27

661 Opioidergic activation of descending pain inhibitory system underlies placebo analgesia

Neyama, H.; Wu, Y.; Nakaya, Y.; Kato, S.; Shimizu, T.; Tahara, T.; Shigeta, M.; Inoue, M.; Miyamichi, K.; Matsushita, N.; Mashimo, T.; Miyasaka, Y.; Watanabe, Y.; Kobayashi, M.; Kobayashi, K.; Cui, Y.

10.1101/2023.06.26.546410 — neuroscience — Posted on 2023-06-27

662 A Bioluminescent Activity Dependent (BLADe) Platform for Converting Neuronal Activity to Photoreceptor Activation

Crespo, E. L.; Pal, A.; Prakash, M.; Silvagnoli, A. D.; Zaidi, Z.; Gomez-Ramirez, M.; Tree, M. O.; Shaner, N. C.; Lipscombe, D.; Moore, C. I.; Hochgeschwender, U.

10.1101/2023.06.25.546469 — neuroscience — Posted on 2023-06-27

663 Thermal compensation reduces DNA damage in UV-exposed amphibian larvae: implications for high latitudinal and altitudinal species

Hird, C.; Cramp, R.; Franklin, C. E.

10.1101/2023.06.25.546466 — zoology — Posted on 2023-06-27

664 Freeze dehydration vs. supercooling in tree stems: physical and physiological modelling

Bozonnet, C.; Saudreau, M.; Badel, E.; Ameglio, T.; Charrier, G.

10.1101/2023.06.26.546491 — biophysics — Posted on 2023-06-27

665 FM3VCF: A Software Library for Accelerating the Loading of Large VCF Files in Genotype Data Analyses

Zuo, Z.; Li, Q.; Li, Z.; Huang, M.; Tang, Y.

10.1101/2023.06.25.546413 — bioinformatics — Posted on 2023-06-27

666 Demographic disequilibrium and growth-mortality asymmetry of forests across climate gradients

Zhou, J.

10.1101/2023.06.25.546473 — ecology — Posted on 2023-06-27

667 Propofol Mediated Unconsciousness Disrupts Progression of Sensory Signals through the Cortical Hierarchy

Tauber, J. M.; Brincat, S. L.; Stephen, E. P.; Donoghue, J. A.; Kozachkov, L.; Brown, E. N.; Miller, E. K.

10.1101/2023.06.25.546463 — neuroscience — Posted on 2023-06-27

668 A cytokinetic ring-driven cell rotation achieves Hertwig's rule in early development

Middelkoop, T. C.; Neipel, J.; Cornell, C. E.; Naumann, R.; Pimpale, L. G.; Julicher, F.; Grill, S. W.

10.1101/2023.06.23.546115 — developmental biology — Posted on 2023-06-27

669 ATP10A promotes endothelial cell insulin sensitivity and protects against diet-induced dyslipidemia in female mice

Norris, A. C.; Yazlovitskaya, E. M.; Zhu, L.; Rose, B. S.; Mansueto, A.; Gibson-Corley, K. N.; May, J. C.; McLean, J. A.; Stafford, J. M.; Graham, T. R.

10.1101/2023.06.16.545392 — molecular biology — Posted on 2023-06-27

670 Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition

Kavanaugh, L. G.; Mahoney, A. R.; Dey, D.; Wuest, W. M.; Conn, G. L.

10.1101/2023.03.24.533986 — microbiology — Posted on 2023-06-27

671 A non-oscillatory, millisecond-scale embedding of brain state provides insight into behavior.

Parks, D. F.; Schneider, A. M.; Xu, Y.; Brunwasser, S. J.; Funderburk, S.; Thurber, D.; Blanche, T.; Dyer, E. L.; Haussler, D.; Hengen, K. B.

10.1101/2023.06.09.544399 — neuroscience — Posted on 2023-06-27

672 Cell type and condition specific functional annotation of schizophrenia associated non-coding genetic variants

Rummel, C. K.; Gagliardi, M.; Herholt, A.; Ahmad, R.; Murek, V.; Weigert, L.; Hausruckinger, A.; Maidl, S.; Jimenez-Barron, L.; Trastulla, L.; Hauger, B.; Eder, M.; Rossner, M. J.; Ziller, M. J.

10.1101/2023.06.27.545266 — genomics — Posted on 2023-06-27

673 The role of embryonic origins and suture proximity in repair of cranial bone

Doro, D.; Liu, A.; Lau, J. S.; Rajendran, A. K.; Healy, C.; Grigoriadis, A. E.; Iseki, S.; Liu, K. J.

10.1101/2023.06.27.546687 — developmental biology — Posted on 2023-06-27

674 Extracellular vesicle-mediated trafficking of developmental cues is altered during human brain disease

Pipicelli, F.; Forero, A.; Moser, S.; Di Matteo, F.; Baumann, N.; Graetz, C.; Gonzalez Pisfil, M.; Bekjarova, Z.; Pfaffl, M.; Canafoglia, L.; Puetz, B.; Kielkowski, P.; Cernilogar, F.; Maccarrone, G.; Jabaudon, D.; Di Giaimo, R.; Cappello, S.

10.1101/2023.06.27.546646 — developmental biology — Posted on 2023-06-27

675 Cross regional coordination of neural activity in the human brain during autobiographical self-referential processing

Stieger, J.; Pinheiro-Chagas, P.; Fang, Y.; Lusk, Z.; Perry, C.; Wagner, A. D.; Contreras, D.; Chen, Q.; Huguenard, J.; Buch, V.; Parvizi, J.

10.1101/2023.06.26.546582 — neuroscience — Posted on 2023-06-27

676 Time dependent effects of cerebellar tDCS on cerebello-cortical connectivity networks in young adults

Maldonado, T.; Jackson, T. B.; Bernard, J. A.

10.1101/2023.06.26.546626 — neuroscience — Posted on 2023-06-27

677 Structure and dynamics of endogenous protein complexes in human heart tissue captured by native nanoproteomics

Chapman, E. A.; Roberts, D. S.; Tiambeng, T. N.; Andrews, J.; Wang, M.-D.; Reasoner, E. A.; Melby, J. A.; Li, B. H.; Kim, D.; Alpert, A. J.; Jin, S.; Ge, Y.

10.1101/2023.06.13.544817 — biochemistry — Posted on 2023-06-27

678 Spatial correspondence in relative space regulates serial dependence

Lim, J.; Lee, S.-H.

10.1101/2023.06.27.546681 — animal behavior and cognition — Posted on 2023-06-27

679 The origin and structural evolution of de novo genes in Drosophila

Peng, J.; Zhao, L.

10.1101/2023.03.13.532420 — evolutionary biology — Posted on 2023-06-27

680 Cortical beta power reflects a neural implementation of decision boundary collapse in speeded decisions

Kirschner, H.; Fischer, A. G.; Danielmeier, C.; Klein, T. A.; Ullsperger, M.

10.1101/2023.01.13.523918 — neuroscience — Posted on 2023-06-27

681 Action does not enhance but attenuates predicted touch

Job, X.; Kilteni, K.

10.1101/2023.04.03.535383 — neuroscience — Posted on 2023-06-27

682 Spatial Heterogeneity of Brain Lipids in SIV-infected Macaques Treated with Antiretroviral Therapy

White, C. J.; Gausepohl, A. M.; Wilkins, H. N.; Eberhard, C. D.; Orsburn, B. C.; Williams, D. W.

10.1101/2022.09.26.508302 — pathology — Posted on 2023-06-27

683 A whole organism map of X-inactivation reveals tissue-specific escape as an exceptionally rare event in humans

Gylemo, B.; Nestor, C. E.

10.1101/2023.06.26.546519 — genetics — Posted on 2023-06-27

684 Single-cell transcriptomic analyses reveal the cellular and genetic basis of aquatic locomotion in scyphozoan jellyfish

Li, Y.; Peng, S.; Liu, Y.; He, K.; Sun, K.; Yu, Z.; Ma, Y.; Wang, F.; Xu, P.; Sun, T.; Zheng, H.; Ye, L.; Wang, L.; Hao, W.; Zhao, J.; Lin, Q.; Chen, K.; Dong, Z.

10.1101/2023.02.06.527379 — ecology — Posted on 2023-06-27

685 scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular building blocks of the primary pacemaker

Abu Nahia, K.; Sulej, A.; Migdal, M.; Ochocka, N.; Ho, R.; Kaminska, B.; Zagorski, M.; Winata, C.

10.1101/2023.06.26.546508 — developmental biology — Posted on 2023-06-27

686 Genetic atlas of hygro- and thermosensory cells in the vinegar fly Drosophila melanogaster

Corthals, K.; Andersson, V.; Churcher, A. M.; Reimegaard, J.; Enjin, A.

10.1101/2023.06.26.546511 — neuroscience — Posted on 2023-06-27

687 Short-term intermittent hypoxia therapy promotes gliogenesis in a rat model of middle cerebral artery occlusion (MCAO) stroke

Roshan, S. A.; Gunaseelan, D.; Swaminathan, J.; Kandasamy, M.; Muthuswamy, A.

10.1101/2023.06.26.546509 — neuroscience — Posted on 2023-06-27

688 Vibrio cholerae phage ICP3 requires O1 antigen for infection

Beckman, D. A.; Waters, C. M.

10.1101/2023.01.31.526503 — microbiology — Posted on 2023-06-27

689 Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues

Glaser, A.; Chandrashekar, J.; Vasquez, J.; Arshadi, C.; Ouellette, N.; Jiang, X.; Baka, J.; Kovacs, G.; Woodard, M.; Seshamani, S.; Cao, K.; Clack, N.; Recknagel, A.; Grim, A.; Balaram, P.; Turschak, E.; Liddell, A.; Rohde, J.; Hellevik, A.; Takasaki, K.; Erion Barner, L.; Logsdon, M.; Chronopoulos, C.; de Vries, S.; Ting, J.; Perlmutter, S.; Kalmbach, B.; Dembrow, N.; Reid, R. C.; Feng, D.; Svoboda, K.

10.1101/2023.06.08.544277 — neuroscience — Posted on 2023-06-27

690 The mechanism of Atg15-mediated membrane disruption in autophagy

Kawamata, T.; Kagohashi, Y.; Ohsumi, Y.; Sasaki, M.; May, A. I.

10.1101/2023.06.26.546516 — biochemistry — Posted on 2023-06-27

691 Heterozygous transcriptional signatures unmask variable premature termination codon (PTC) burden alongside pathway-specific adaptations in blood outgrowth endothelial cells from patients with nonsense DNA variants causing hereditary hemorrhagic telangiectasia

Bernabeu-Herrero, M. E.; Patel, D.; Bielowka, A.; Chaves Guerrero, P.; Marciniak, S. J.; Noseda, M.; Aldred, M. A.; Shovlin, C. L.

10.1101/2021.12.05.471269 — cell biology — Posted on 2023-06-27

692 Isolation of a Chlamydia Strain from Lung Tissue Samples in Healthy Chickens Exhibiting Antagonistic Effects on Avian Infectious Bronchitis Virus

Zhen, M.

10.1101/2023.05.10.540153 — microbiology — Posted on 2023-06-27

693 Variability of visual field maps in human early extrastriate cortex challenges the canonical model of organization of V2 and V3

Ribeiro, F. L.; York, A.; Zavitz, E.; Bollmann, S.; Rosa, M. G. P.; Puckett, A. M.

10.1101/2022.10.16.511648 — neuroscience — Posted on 2023-06-27

694 Foraging specialization and body size in seabirds

Hernandez, J. C.; Arroyo, J. I.

10.1101/2023.06.25.546462 — ecology — Posted on 2023-06-27

695 Evaluation of nucleic acid binding site of SARS-CoV-2 nucleocapsid as a potential antiviral target using small molecule inhibitors

Dhaka, P.; Singh, A.; Choudhary, S.; Peddinti, R. K.; Kumar, P.; Sharma, G. K.; Tomar, S.

10.1101/2022.03.12.484092 — molecular biology — Posted on 2023-06-27

696 Nanopore long-reads reveal fine structure of prokaryotic communities in mangrove sediments, like Illumina short-reads but with twice more taxa

Lemoinne, A.; Dirberg, G.; Georges, M.; Robinet, T.

10.1101/2023.06.06.541006 — molecular biology — Posted on 2023-06-27

697 Spatial subdomains in the Optic Tectum for the encoding of visual information

Shallcross, T.; Diana, G.; Burrone, J.; Meyer, M. P.

10.1101/2023.05.15.540762 — neuroscience — Posted on 2023-06-27

698 Robust estimation of brain stimulation evoked responses using magnetoencephalography

Oswal, A.; Abdi-Sargezeh, B.; Ozkurt, T. E.; Taulu, S.; Sarangmat, N.; Green, A. L.; Litvak, V.

10.1101/2023.06.25.546459 — bioengineering — Posted on 2023-06-27

699 Spontaneous activity in peripheral sensory nerves - A systematic review

Choi, D.; Goodwin, G.; Stevens, E. B.; Soliman, N.; Namer, B.; Denk, F.

10.1101/2023.06.13.544736 — neuroscience — Posted on 2023-06-27

700 Empirical methods for the validation of Time-To-Event mathematical models taking into account uncertainty and variability: Application to EGFR+ Lung Adenocarcinoma.

Jacob, E.; Perrillat-Mercerot, A.; Palgen, J.-L.; L'Hostis, A.; Ceres, N.; Boissel, J.-P.; Bosley, J.; Monteiro, C.; Kahoul, R.

10.1101/2022.09.08.507079 — systems biology — Posted on 2023-06-27

701 Ancient Sheep Genomes reveal four Millennia of North European Short-Tailed Sheep in the Baltic Sea region

Larsson, M. N.; Morell Miranda, P.; Pan, L.; Basak Vural, K.; Kaptan, D.; Rodrigues Soares, A. E.; Kivikero, H.; Kantanen, J.; Somel, M.; Özer, F.; Johansson, A. M.; Stora, J.; Günther, T.

10.1101/2023.06.26.544912 — evolutionary biology — Posted on 2023-06-27

702 Spatial subdomains in the Optic Tectum for the encoding of visual information

Shallcross, T.; Diana, G.; Burrone, J.; Meyer, M. P.

10.1101/2023.05.15.540762 — neuroscience — Posted on 2023-06-27

703 Simulation-based inference for efficient identification of generative models in connectomics

Boelts, J.; Harth, P.; Gao, R.; Udvary, D.; Yanez, F.; Baum, D.; Hege, H.-C.; Oberlaender, M.; Macke, J. H.

10.1101/2023.01.31.526269 — neuroscience — Posted on 2023-06-27

704 Adaptive biasing of action-selective cortical build-upactivity by stimulus history

Braun, A.; Donner, T. H.

10.1101/2022.11.21.516403 — neuroscience — Posted on 2023-06-27

705 Fast 2-photon stimulation using holographic patterns

Brunstein, M.; Lubetzki, J.; Moutoussamy, C.; Li, W.; Barral, J.

10.1101/2023.01.12.523269 — neuroscience — Posted on 2023-06-27

706 A Theory of Hippocampal Theta Correlations: Extrinsic and Intrinsic Sequences

Yiu, Y.-H.; Leibold, C.

10.1101/2023.02.05.527133 — neuroscience — Posted on 2023-06-27

707 Broca's area, variation and taxic diversity in early Homo from Koobi Fora (Kenya)

Beaudet, A.; de Jager, E.

10.1101/2023.06.05.543693 — evolutionary biology — Posted on 2023-06-27

708 The impact of Quaternary Amazonian river dynamics on patterns and process of diversification in uakari monkeys (genus Cacajao)

Silva, F. E.; Luna, L. W.; Batista, R.; Rhöe, F.; Gubili, C.; Farias, I. P.; Hrbek, T.; do Amaral, J. V.; Ribas, C. C.; McDevitt, A. D.; Dellicour, S.; Flot, J.-F.; Boubli, J. P.

10.1101/2023.06.23.546215 — evolutionary biology — Posted on 2023-06-27

709 Expression and Splicing Mediate Distinct Biological Signals

Helweg Dam, S.; Olsen, L. R.; Vitting-Seerup, K.

10.1101/2022.08.29.505720 — molecular biology — Posted on 2023-06-27

710 Deep speech-to-text models capture the neural basis of spontaneous speech in everyday conversations

Goldstein, A.; Wang, H.; Niekerken, L.; Zada, Z.; Aubrey, B.; Sheffer, T.; Nastase, S. A.; Gazula, H.; Schain, M.; Singh, A.; Rao, A.; Choe, G.; Kim, C.; Doyle, W.; Friedman, D.; Devore, S.; Dugan, P.; Hassidim, A.; Brenner, M.; Matias, Y.; Devinsky, O.; Flinker, A.; Hasson, U.

10.1101/2023.06.26.546557 — neuroscience — Posted on 2023-06-27

711 Gradient organisation of functional connectivity within resting state networks is present from 25 weeks gestation in the human fetal brain

Moore, J. W.; Wilson, S.; Oldehinkel, M.; Cordero-Grande, L.; Uus, A.; Kyriakopoulou, V.; Duff, E.; O'Muircheartaigh, J.; Rutherford, M.; Andreae, L. C.; Hajnal, J. V.; Edwards, D.; Beckmann, C.; Arichi, T.; Karolis, V. R.

10.1101/2023.06.26.546607 — neuroscience — Posted on 2023-06-27

712 Rats synchronize predictively to metronomes

Rajendran, V. G.; Tsdaka, Y.; Keung, T. Y.; Schnupp, J. W. H.; Nelken, I.

10.1101/2023.06.19.545615 — neuroscience — Posted on 2023-06-27

713 Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects

10.1101/2023.06.26.546528 — genetics — Posted on 2023-06-27

714 High density SNP array and reanalysis of genome sequencing uncovers CNVs associated with neurodevelopmental disorders in KOLF2.1J iPSCs

Gracia-Diaz, C.; Perdomo, J. E.; Khan, M. E.; Disanza, B.; Cajka, G. G.; Leis, S.; Gagne, A.; Maguire, J. A.; Roule, T.; Shalem, O.; Bhoj, E. J.; Ahrens-Nicklas, R. C.; French, D.; Goldberg, E. M.; Wang, K.; Glessner, J.; Akizu, N.

10.1101/2023.06.26.546614 — genetics — Posted on 2023-06-27

715 Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism

Anandachar, M. S.; Agyekum, B.; Sinha, S.; Roy, S.; Ibeawuchi, S.-R.; Gementera, H.; Amamoto, A.; Katkar, G. D.; Ghosh, P.

10.1101/2023.04.09.536168 — immunology — Posted on 2023-06-26

716 Profiling intra- and inter-individual differences in brain development across early adolescence

Bottenhorn, K. L.; Cardenas-Iniguez, C.; Mills, K. L.; Laird, A. R.; Herting, M. M.

10.1101/2022.12.19.521089 — neuroscience — Posted on 2023-06-26

717 Engaged decision-makers align spontaneous movements to stereotyped task demands

Yin, C.; Melin, M.; Rojas-Bowe, G.; Couto, J.; Sun, X.; Gluf, S.; Kostiuk, A.; Musall, S.; Churchland, A. K.

10.1101/2023.06.26.546404 — neuroscience — Posted on 2023-06-26

718 Cortical over-representation of phonetic onsets of ignored speech in hearing impaired individuals

Carta, S.; Alickovic, E.; Zaar, J.; Lopez Valdes, A.; Di Liberto, G.

10.1101/2023.06.26.546549 — neuroscience — Posted on 2023-06-26

719 Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

Cook, A. A.; Leung, T. C. S.; Rice, M.; Nachman, M.; Zadigue-Dube, E.; Watt, A. J.

10.1101/2023.06.26.546542 — neuroscience — Posted on 2023-06-26

720 Compensation between FOXP transcription factors maintains proper striatal function

Ahmed, N. I.; Khandelwal, N.; Anderson, A. G.; Kulkarni, A.; Gibson, J.; Konopka, G.

10.1101/2023.06.26.546567 — neuroscience — Posted on 2023-06-26

721 Bats possess the anatomical substrate for a laryngeal motor cortex

Nevue, A. A.; Mello, C. V.; Portfors, C. V.

10.1101/2023.06.26.546619 — neuroscience — Posted on 2023-06-26

722 Optimizer's dilemma: optimization strongly influences model selection in transcriptomic prediction

Crawford, J.; Chikina, M.; Greene, C. S.

10.1101/2023.06.26.546586 — bioinformatics — Posted on 2023-06-26

723 Clonal neural tube organoids self-organise floorplate through BMP-mediated cluster competition

Krammer, T.; Stuart, H. T.; Gromberg, E.; Ishihara, K.; Melchionda, M.; Wang, J.; Costantini, E.; Lehr, S.; Cislo, D.; Arbanas, L.; Hoermann, A.; Neumueller, R. A.; Elvassore, N.; Siggia, E.; Briscoe, J.; Kicheva, A.; Tanaka, E. M.

10.1101/2023.06.25.546258 — developmental biology — Posted on 2023-06-26

724 Combinatorial selective ER-phagy remodels the ER during neurogenesis

Hoyer, M. J.; Smith, I. R.; Paoli, J. C.; Jiang, Y.; Paulo, J. A.; Harper, W.

10.1101/2023.06.26.546565 — cell biology — Posted on 2023-06-26

725 Pushed to the edge: hundreds of myosin 10s pack into filopodia and could cause traffic jams on actin

Shangguan, J.; Rock, R. S.

10.1101/2023.06.26.546598 — cell biology — Posted on 2023-06-26

726 SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss

Spits, C.; Lei, Y.; Al Delbany, D.; Krivec, N.; Regin, M.; Couvreu de Deckersberg, E.; Janssens, C.; Ghosh, M.; Sermon, K. D.

10.1101/2023.06.26.546513 — cell biology — Posted on 2023-06-26

727 Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB

Wu, H.; Zhou, L.-Y.; Jin, C.-X.; Wang, W.-X.; Song, L.; Shin, J.-B.; Du, T.-T.

10.1101/2023.06.26.546585 — cell biology — Posted on 2023-06-26

728 Mitogenome fragmentation evolves multiple times within a major group of parasitic lice

Najer, T.; Dona, J.; Bucek, A.; Sweet, A. D.; Sychra, O.; Johnson, K. P.

10.1101/2023.06.22.546119 — molecular biology — Posted on 2023-06-26

729 CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

Lambert, G. G.; Crespo, E. L.; Murphy, J.; Boassa, D.; Luong, S.; Hu, J.; Sprecher, B.; Tree, M. O.; Orcutt, R.; Heydari, D.; Bell, A. B.; Torreblanca Zanca, A.; Hakimi, A.; Lipscombe, D.; Moore, C. I.; Hochgeschwender, U.; Shaner, N. C.

10.1101/2023.06.25.546478 — neuroscience — Posted on 2023-06-26

730 Effective mechanical potential of cell-cell interaction explains three-dimensional morphologies during early embryogenesis

Koyama, H.; Okumura, H.; Ito, A. M.; Nakamura, K.; Otani, T.; Kato, K.; Fujimori, T.

10.1101/812198 — biophysics — Posted on 2023-06-26

731 Molecule-Morphology Contrastive Pretraining for Transferable Molecular Representation

Nguyen, C. Q.; Pertusi, D.; Branson, K. M.

10.1101/2023.05.01.538999 — bioinformatics — Posted on 2023-06-26

732 A global test of hybrid ancestry from genome-scale data

Haque, M. R.; Kubatko, L.

10.1101/2023.02.24.529943 — bioinformatics — Posted on 2023-06-26

733 The Structural Layers of the Porcine Iris Exhibit Inherently Different Biomechanical Properties

Tan, R. K. Y.; Panda, S. K.; Braeu, F. A.; Muralidharan, A. R.; Nongpiur, M. E.; Chan, A. S. Y.; Aung, T.; Najjar, R. P.; Girard, M. J. A.

10.1101/2022.12.11.519999 — bioengineering — Posted on 2023-06-26

734 Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stresses

Wang, J.; Wen, Y.; Zhao, W.; Zhang, Y.; Lin, F.; Ouyang, C.; Wang, H.; Yao, L.; Ma, H.; Zhuo, Y.; Huang, H.; Shi, X.; Feng, L.; Lin, D.; Jiang, B.; Li, Q.

10.1101/2023.03.23.533947 — biochemistry — Posted on 2023-06-26

735 A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer's disease models

Xu, D.; Vincent, A.; Gonzalez, A.; Aleyakpo, B.; Anoar, S.; Giblin, A.; Atilano, M.; Adams, M.; Shen, D.; Thoeng, A.; Tsintzas, E.; Maeland, M.; Isaacs, A. M.; Sierralta, J.; Niccoli, T.

10.1101/2023.06.25.546435 — neuroscience — Posted on 2023-06-26

736 Lysosomal mitochondrial interaction promotes tumor growth in squamous cell carcinoma of the head and neck

Gopalkrishnan, A.; Wang, N.; Cruz-Rangel, S.; Yassin-Kassab, A.; Shiva, S.; Kurukulasuriya, C.; Monga, S. P.; DeBerardinis, R. J.; Kiselyov, K.; Duvvuri, U.

10.1101/2023.06.25.546311 — cancer biology — Posted on 2023-06-26

737 Development and validation of NAD+ metabolism-related gene signature in prognosis prediction ofhepatocellular carcinoma

Du, Y.

10.1101/2023.06.25.546472 — cancer biology — Posted on 2023-06-26

738 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seeding experiments

Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.

10.1101/2023.06.25.546428 — biophysics — Posted on 2023-06-26

739 Rapid and accurate multi-phenotype imputation for millions of individuals

Gu, L.-L.; Chen, G.-B.; Wu, H.-S.; Zhang, Y.-J.; He, J.-C.; Liu, X.-L.; Wang, Z.-Y.; Jiang, D.; Fang, M.

10.1101/2023.06.25.546422 — bioinformatics — Posted on 2023-06-26

740 Small allelic variants are a source of ancestral bias in structural variant breakpoint placement

Audano, P. A.; Beck, C. R.

10.1101/2023.06.25.546295 — bioinformatics — Posted on 2023-06-26

741 PepFlow: direct conformational sampling from peptide energy landscapes through hypernetwork-conditioned diffusion

Abdin, O.; Kim, P. M.

10.1101/2023.06.25.546443 — bioinformatics — Posted on 2023-06-26

742 CRISPR/Cas9 DNA synthesis disruption as a tool to control cell proliferation in vitro and in vivo

Sartori-Maldonado, R.; Montaser, H.; Soppa, I.; Balaz, M.; Puttonen, H.; Eurola, S.; Otonkoski, T.; Saarimaki-Vire, J.; Wartiovaara, K.

10.1101/2023.06.26.546441 — bioengineering — Posted on 2023-06-26

743 Depletion of lamins B1 and B2 alters chromatin mobility and induces differential gene expression by a mesoscale-motion dependent mechanism

Pujadas, E. M.; Wei, X.; Acosta, N.; Carter, L.; Yang, J.; Almassalha, L.; Daneshkhah, A.; Rao, S. S. P.; Agrawal, V.; Seker-Polat, F.; Aiden, E. L.; Kanemaki, M. T.; Backman, V.; Adli, M.

10.1101/2023.06.26.546573 — bioengineering — Posted on 2023-06-26

744 USP16 is an ISG15 cross-reactive deubiquitinase targeting a subset of metabolic pathway-related proteins

Gan, J.; Pinto-Fernandez, A.; Flierman, D.; Akkermans, J. J. L. L.; O'Brien, D. P.; Greenwood, H.; Scott, H. C.; Neefjes, J.; Fritz, G.; Knobeloch, K.-P.; van Dam, H.; Kessler, B. M.; Ovaa, H.; Geurink, P. P.; Sapmaz, A.

10.1101/2023.06.26.546496 — biochemistry — Posted on 2023-06-26

745 Unmasking Crucial Residues in Adipose Triglyceride Lipase (ATGL) for Co-Activation with Comparative Gene Identification-58 (CGI-58)

Kulminskaya, N.; Rodriguez Gamez, C. F.; Hofer, P.; Cerk, I. K.; Dubey, N.; Viertlmayr, R.; Sagmeister, T.; Pavkov-Keller, T.; Zechner, R.; Oberer, M.

10.1101/2023.06.26.546551 — biochemistry — Posted on 2023-06-26

746 Endocannabinoid system modulation alters fine motor behavior in mice: insights from 3D motion capture

Ignatowska-Jankowska, B. M.; Gurkan Ozer, A.; Kuck, A.; Niphakis, M. J.; Ogasawara, D.; Cravatt, B. F.; Uusisaari, M. Y.

10.1101/2023.06.25.546437 — animal behavior and cognition — Posted on 2023-06-26

747 Transcriptomics Reveals Tumorigenesis and Pathogen Response in Scombrid Puffy Snout Syndrome

Leidholt, S. L.; Galvin, T.; Miller, E.; Bistolas, K.; Van Houtan, K.; Boustany, A.; Vega Thurber, R.

10.1101/2023.06.26.546572 — genomics — Posted on 2023-06-26

748 HPC-based genome variant calling workflow (HPC-GVCW)

Zhou, Y.; Kathiresan, N.; Yu, Z.; Rivera, L. F.; Thimma, M.; Manickam, K.; Chebotarov, D.; Mauleon, R.; Chougule, K.; Wei, S.; Gao, T.; Green, C. D.; Zuccolo, A.; Zhang, J.; Ware, D.; McNally, K. L.; Wing, R. A.

10.1101/2023.06.25.546420 — genomics — Posted on 2023-06-26

749 Classification of patients with COVID-19 by blood RNA endotype: A prospective cohort study

Yoshimura, J.; Togami, Y.; Ebihara, T.; Matsumoto, H.; Mitsuyama, Y.; Sugihara, F.; Hirata, H.; Okuzaki, D.; Ogura, H.

10.1101/2023.06.22.546100 — genetics — Posted on 2023-06-26

750 Two independent DNA repair pathways cause mutagenesis in template switching deficient Saccharomyces cerevisiae

Jiang, Y. K.; Medley, E. A.; Brown, G. W.

10.1101/2023.06.25.546467 — genetics — Posted on 2023-06-26

751 Reactivation of an errantivirus in Drosophila ovarian somatic tissue: from germline invasion to taming

Yoth, M.; Maupetit Mehouas, S.; Akkouche, A.; Gueguen, N.; Jensen, S.; Brasset, E.

10.1101/2022.08.29.505639 — genetics — Posted on 2023-06-26

752 Rapid species discovery and identification with real-time barcoding facilitated by ONTbarcoder 2.0 and Oxford Nanopore R10.4

Srivathsan, A.; Feng, V.; Ramos, D.; Meier, R.

10.1101/2023.06.26.546538 — ecology — Posted on 2023-06-26

753 Severe fire regimes select for highly resilient populations in ectotherms

Sousa, H. C.; Malvasio, A.; Colli, G. R.; Salguero-Gomez, R. C.

10.1101/2023.06.25.546448 — ecology — Posted on 2023-06-26

754 Mutant analysis of Kcng4b reveals how the different functional states of the voltage-gated potassium channel regulate ear development

Jedrychowska, J.; Vardanian, V.; Wieczor, M.; Marciniak, A.; Amini, R.; Jain, R.; Shen, H.; Choi, H.; Kuznicki, J.; Korzh, V.

10.1101/2023.06.26.546501 — developmental biology — Posted on 2023-06-26

755 Cell Type- and Tissue-specific Enhancers in Craniofacial Development

Rajderkar, S. S.; Paraiso, K.; Amaral, M. L.; Kosicki, M.; Cook, L.; Darbellay, F.; Spurrell, C.; Osterwalder, M.; Zhu, Y.; Wu, H.; Afzal, S. Y.; Blow, M.; Kelman, G.; Barozzi, I.; Fukuda-Yuzawa, Y.; Akiyama, J. A.; Afzal, V.; Tran, S.; Plajzer-Frick, I.; Novak, C. S.; Kato, M.; Hunter, R. D.; von Maydell, K.; Wang, A.; Lin, L.; Preissl, S.; Lisgo, S.; Ren, B.; Dickel, D. E.; Pennacchio, L. A.; Visel, A.

10.1101/2023.06.26.546603 — developmental biology — Posted on 2023-06-26

756 Isolation of stage-specific spermatogenic cells by dynamic histone incorporation and removal in spermatogenesis.

Fujiwara, Y.; Hada, M.; Fukuda, Y.; Koga, C.; Inoue, E.; Okada, Y.

10.1101/2023.06.25.546481 — developmental biology — Posted on 2023-06-26

757 A Highly Efficient Aorta-Gonad-Mesonephros-Like Definitive Hemogenic Endothelium From Human Pluripotent Stem Cells

Fstkchyan, Y.; Cheng, Q.; Zhang, J. A.; Lu, D.; Huang, G.; Dong, T.; Jones, L.; Kanke, M.; Hale, C.; Tarbell, K.; Li, C.-M. K.; Wang, S.; Chambers, S.

10.1101/2023.06.26.546545 — developmental biology — Posted on 2023-06-26

758 Patterning and folding of intestinal villi by active mesenchymal dewetting

Huycke, T. R.; Miyazaki, H.; Häkkinen, T.; Srivastava, V.; Barruet, E.; McGinnis, C. S.; Kalantari, A.; Cornwall-Scoones, J.; Vaka, D.; Zhu, Q.; Jo, H.; DeGrado, W. F.; Thomson, M.; Garikipati, K.; Boffelli, D.; Klein, O. D.; Gartner, Z. J.

10.1101/2023.06.25.546328 — developmental biology — Posted on 2023-06-26

759 Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins

Goncalves, D. L.; Peffer, S.; Morano, K. A.

10.1101/2023.06.26.546610 — cell biology — Posted on 2023-06-26

760 HD mutation results in a dominant negative effect on HTT function

Laundos, T. L.; Li, S.; Cheang, E.; De Santis, R.; Piccolo, F. M.; Brivanlou, A. H.

10.1101/2023.06.26.543767 — cell biology — Posted on 2023-06-26

761 Genetic Screen Identified Prmt5 as a Neuroprotection Target against Cerebral Ischemia

Wu, H.; Lv, P.; Wang, J.; Bennett, B.; Wang, J.; Li, P.; Peng, Y.; Hu, G.; Lin, J.

10.1101/2023.06.26.546470 — cell biology — Posted on 2023-06-26

762 Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals

Jones, B. T.; Han, J.; Zhang, H.; Hammer, R. E.; Evers, B. M.; Rakheja, D.; Acharya, A.; Mendell, J. T.

10.1101/2023.06.26.546601 — molecular biology — Posted on 2023-06-26

763 SAP domain facilitates efficient loading of Ku onto DNA ends

Fulnecek, J.; Klimentova, E.; Cairo, A.; Valuchova Bukovcakova, S.; Alexiou, P.; Prokop, Z.; Riha, K.

10.1101/2023.06.26.546499 — molecular biology — Posted on 2023-06-26

764 Investigating Metabolic Trends in the Oral Cavity to Identify Novel Metabolites

Okiye, M. E. K.; Velez, M.; Kinney, J.; Van Sugai, J.; Giannobile, W.; Tripathi, A.; Sherman, D. H.

10.1101/2023.06.26.546600 — molecular biology — Posted on 2023-06-26

765 A comprehensive overview of the Chloroflexota community in wastewater treatment plants worldwide

Petriglieri, F.; Kondrotaite, Z.; Singleton, C. M.; Nierychlo, M.; Dueholm, M. S.; Nielsen, P. H.

10.1101/2023.06.26.546502 — microbiology — Posted on 2023-06-26

766 Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches

Procknow, R. R.; Kennedy, K. J.; Kluba, M.; Rodriguez, L. J.; Taga, M. E.

10.1101/2023.06.26.546531 — microbiology — Posted on 2023-06-26

767 Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice

Watanabe, Y.; Fujisaka, S.; Morinaga, Y.; Watanabe, S.; Nawaz, A.; Hatta, H.; Kado, T.; Nishimura, A.; Bilal, M.; Aslam, M. R.; Honda, K.; Nakagawa, Y.; Softic, S.; Hirabayashi, K.; Nakagawa, T.; Nagai, Y.; Tobe, K.

10.1101/2023.06.21.543373 — microbiology — Posted on 2023-06-26

768 A low dimensional manifold of human exploration and exploitation behavior reveals states of apathy and anxiety

Yan, X.; Ebitz, B.; Grissom, N.; Darrow, D.; Herman, A.

10.1101/2023.06.19.545645 — neuroscience — Posted on 2023-06-26

769 G2C4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in C9orf72 ALS/FTD human neurons

Rothstein, J. D.; Baskerville, V.; Rapuri, S.; Mehlhop, E.; Jafar-nejad, P.; Rigo, F.; Bennett, F.; Mizielinska, S.; Isaacs, A.; Coyne, A. N.

10.1101/2023.06.26.546581 — neuroscience — Posted on 2023-06-26

770 How rate information is collectively coded in input to the cerebellum: a hypothesis and simulation

Gilbert, M.; Rasmussen, A.

10.1101/2023.06.25.546423 — neuroscience — Posted on 2023-06-26

771 C2CAplus: a one-pot isothermal circle-to-circle DNA amplification system

Grasemann, L.; Pizarro, P. T.; Maerkl, S. J.

10.1101/2023.06.26.546530 — synthetic biology — Posted on 2023-06-26

772 In vitro construction and long read sequencing analysis of a 24 kb long artificial DNA sequence encoding the Universal Declaration of the Rights of Man and of the Citizen.

Leblanc, J.; Boulle, O.; Roux, E.; Nicolas, J.; Lavenier, D.; Audic, Y.

10.1101/2023.06.26.546242 — synthetic biology — Posted on 2023-06-26

773 Convergent Gene Expression Patterns During Compatible Interactions Between Two Pseudomonas syringae Pathovars and a Common Host (Nicotiana benthamiana)

Carter, M. E.; Smith, A.; Baltrus, D. A.; Kvitko, B.

10.1101/2022.06.26.497614 — plant biology — Posted on 2023-06-26

774 Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor

Ciampa, E. J.; Flahardy, P.; Srinivasan, H.; Jacobs, C.; Tsai, L.; Karumanchi, S. A.; Parikh, S. M.

10.1101/2022.03.14.483784 — physiology — Posted on 2023-06-26

775 Safety Assessment and Evaluation of Novel Thiourea Derivatives as Antivirals

Kumar, J.; Tyagi, P.; saini, a. k.; Sharma, D.; Kumar, V.

10.1101/2023.06.25.546447 — pharmacology and toxicology — Posted on 2023-06-26

776 Reciprocating RNA Polymerase batters throughroadblocks

Qian, J.; Cartee, A. G.; Xu, W.; Yan, Y.; Wang, B.; Artsimovitch, I.; Dunlap, D.; Finzi, L.

10.1101/2023.01.04.522798 — biophysics — Posted on 2023-06-26

777 Protein engineering, production, reconstitution in lipid nanoparticles, and initial characterization of the Mycobacterium tuberculosis EfpA drug exporter

Ishola, O.; Ogunbowale, A.; Islam, M. M.; Hadadianpour, E.; Majeed, S.; Adetuyi, O.; Georgieva, E. R.

10.1101/2023.06.26.546575 — biochemistry — Posted on 2023-06-26

778 Dysregulated DnaB unwinding induces replisome decoupling and daughter strand gaps that are countered by RecA polymerization

Behrmann, M. S.; Perera, H. M.; Welikala, M. U.; Matthews, J. E.; Trakselis, M. A.

10.1101/2023.06.26.546485 — biochemistry — Posted on 2023-06-26

779 Locomotor effects of a fibrosis-based immune response in stickleback fish

Matthews, D. G.; Maciejewski, M. F.; Wong, G. A.; Lauder, G. V.; Bolnick, D. I.

10.1101/2023.06.24.546342 — evolutionary biology — Posted on 2023-06-26

780 CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Samelson, A. J.; Ariqat, N.; McKetney, J.; Rohanitazangi, G.; Parra Bravo, C.; Goodness, D.; Tian, R.; Grosjean, P.; Abskharon, R.; Eisenberg, D.; Kanaan, N. M.; Gan, L.; Condello, C.; Swaney, D. L.; Kampmann, M.

10.1101/2023.06.16.545386 — cell biology — Posted on 2023-06-26

781 Synaptopodin is necessary for Shigella flexneri intercellular spread

Vickery, J. M.; Toperzer, J. D.; Raab, J. E.; Lenz, L. L.; Colgan, S. P.; Russo, B. C.

10.1101/2023.04.25.537990 — microbiology — Posted on 2023-06-26

782 Endocrine pancreas-specific Gclc gene deletion causes a severe diabetes phenotype

Davidson, E. A.; Chen, Y.; Singh, S.; Orlicky, D. J.; Thompson, B.; Wang, Y.; Charkoftaki, G.; Furnary, T.; Cardone, R. L.; Kibbey, R. G.; Shearn, C. T.; Nebert, D. W.; Thompson, D. C.; Vasiliou, V.

10.1101/2023.06.13.544855 — physiology — Posted on 2023-06-26

783 Revisiting the role of cAMP in Drosophila aversive olfactory memory formation

Abe, T.; Yamazaki, D.; Hiroi, M.; Ueoka, Y.; Maeyama, Y.; Tabata, T.

10.1101/2023.06.26.545795 — neuroscience — Posted on 2023-06-26

784 Uncovering a stability signature of brain dynamics associated with meditation experience using massive time-series feature extraction

Bailey, N. W.; Fulcher, B. D.; Caldwell, B.; Hill, A. T.; Fitzgibbon, B.; van Dijk, H.; Fitzgerald, P. B.

10.1101/2023.06.23.546355 — neuroscience — Posted on 2023-06-26

785 The influence of the way of regression on the results obtained by the receptorial responsiveness method (RRM), a procedure to estimate a change in the concentration of a pharmacological agonist near the receptor

Ovary, I.; Viczjan, G.; Erdei, T.; Takacs, B.; Szekeres, R.; Lampe, N.; Zsuga, J.; Szucs, M.; Szilvassy, Z.; Juhasz, B.; Gesztelyi, R.

10.1101/2023.06.23.546208 — pharmacology and toxicology — Posted on 2023-06-26

786 Twenty novel nsSNPs may affect FLT3 gene leading to Acute Myeloid Leukemia (AML) using in silico analysis

Alsheikh, T.; Ameer, T.; NjmEldin, A.; Omer, D.; Agbash, A.; Abdalmonem, Z.; Suliman, H.; Hamad, H.; A. ayoub, S. E.; A. Hassan, M.

10.1101/2023.06.24.546344 — bioinformatics — Posted on 2023-06-26

787 Oligomeric state of β-coronavirus non-structural protein 10 stimulators studied by OmniSEC and Small Angle X-ray Scattering

Knecht, W.; Fisher, Z.; Lou, J.; Sele, C.; Ma, S.; Andersson Rasmussen, A.; Pinotsis, N. N.; Kozielski, F. G.

10.1101/2023.06.26.546492 — biochemistry — Posted on 2023-06-26

788 KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution

Otsuka, K.; Sakashita, A.; Maezawa, S.; Schultz, R. M.; Namekawa, S. H.

10.1101/2023.06.24.546405 — genomics — Posted on 2023-06-26

789 Aneuploidies are an ancestral feature of trypanosomatids, and an ancient chromosome duplication is maintained in extant species

Reis-Cunha, J. L.; Carvalho, S. A. P.; Almeida, L. V.; Coqueiro-dos-Santos, A.; Marques, C. D. A.; Black, J.; Damasceno, J.; McCulloch, R.; Bartholomeu, D. C.; Jeffares, D. C.

10.1101/2023.06.26.546280 — genomics — Posted on 2023-06-26

790 Cdk4/6 is activated by DNA hypomethylation to cause DNA rereplication and organ outgrowth defects

Madakashira, B. P.; Magnani, E.; Ranjan, S.; Sadler, K. C.

10.1101/2023.06.26.545878 — developmental biology — Posted on 2023-06-26

791 Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS-COV-2 targeting virus-specific enzymes

Choudhary, S.; Nehul, S.; Singh, A.; Panda, P. K.; Kumar, P.; Sharma, G. K.; Tomar, S.

10.1101/2023.06.24.546363 — molecular biology — Posted on 2023-06-26

792 Wolbachia-mediated resistance to Zika virus infection in Aedes aegypti is dominated by diverse transcriptional regulation and weak evolutionary pressures

Boehm, E. C.; Jaeger, A. S.; Ries, H. J.; Castaneda, D.; Weiler, A. M.; Valencia, C. C.; Weger-Lucarelli, J.; Ebel, G.; O'Connor, S. L.; Friedrich, T. C.; Zamanian, M.; Aliota, M. T.

10.1101/2023.06.26.546271 — molecular biology — Posted on 2023-06-26

793 Persistence of intact HIV-1 proviruses in the brain during suppressive antiretroviral therapy

Sun, W.; Rassadkina, Y.; Gao, C.; Collens, S. I.; Lian, X.; Solomon, I. H.; Mukerji, S. S.; Yu, X. G.; Lichterfeld, M.

10.1101/2023.06.26.546135 — microbiology — Posted on 2023-06-26

794 Synapses without tension fail to fire in an in vitro network of hippocampal neurons.

Joy, M. S. H.; Nall, D. L.; Emon, B.; Lee, K. Y.; Barishman, A.; Ahmed, M.; Rahman, S.; Selvin, P. R.; Saif, M. T. A.

10.1101/2023.06.24.546401 — neuroscience — Posted on 2023-06-26

795 Reactivation of memory-encoding dentate gyrus neurons during memory consolidation is associated with subregion-specific, learning- and sleep-mediated biosynthetic changes

Wang, L.; Park, L.; Wu, W.; King, D.; Medina, A. V.; Raven, F.; Martinez, J. D.; Ensing, A.; McDonald, K.; Yang, Z.; Jiang, S.; Aton, S.

10.1101/2022.11.09.515837 — neuroscience — Posted on 2023-06-26

796 An integrated mechanistic and data-driven computational model predicts cell responses to high- and low-affinity EGFR ligands

Myers, P.; Lee, S. H.; Lazzara, M.

10.1101/2023.06.25.543329 — systems biology — Posted on 2023-06-26

797 Immortalization and transformation of primary cells mediated by engineered ecDNAs

Pradella, D.; Zhang, M.; Gao, R.; Melissa, Y. A.; Gluchowska, K. M.; Cendon Florez, Y.; Mishra, T.; La Rocca, G.; Weigl, M.; Jiao, Z.; Nguyen, H. H. M.; Grimm, F.; Lisi, M.; Mastroleo, C.; Chen, K.; Luebeck, J.; Bafna, V.; Antonescu, C. R.; Ventura, A.

10.1101/2023.06.25.546239 — cancer biology — Posted on 2023-06-26

798 BioLiP2: a database for biological unit-based protein-ligand interactions

Wei, H.; Wang, W.; Peng, Z.; Yang, J.

10.1101/2023.06.23.546351 — bioinformatics — Posted on 2023-06-26

799 Rapid Prototyping of Thermoplastic Microfluidic 3D Cell Culture Devices by Creating Regional Hydrophilicity Discrepancy

Bai, H.; Olson, K. N. P.; Pan, M.; Marshall, T.; Singh, H.; Ma, J.; Gilbride, P.; Yuan, Y.-C.; Si, L.; Maharjan, S.; Huang, D.; Qian, X.; Livermore, C.; Zhang, Y. S.; Xie, X.

10.1101/2023.06.23.546122 — bioengineering — Posted on 2023-06-26

800 Elucidating the heterogeneity of immunotherapy response and immune-related toxicities by longitudinal ctDNA and immune cell compartment tracking in lung cancer

Murray, J. C.; Sivapalan, L.; Hummelink, K.; Balan, A.; White, J. R.; Niknafs, N.; Rhymee, L.; Pereira, G.; Rao, N.; Phallen, J.; Leal, A.; Bartlett, D. L.; Marrone, K. A.; Naidoo, J.; Levy, B.; Rosner, S.; Hann, C. L.; Scott, S. C.; Feliciano, J.; Lam, V. K.; Ettinger, D. S.; Li, Q. K.; Illei, P. B.; Monkhorst, K.; Zaidi, A. H.; Scharpf, R. B.; Brahmer, J. R.; Velculescu, V. E.; Forde, P. M.; Anagnostou, V.

10.1101/2023.06.23.546338 — genomics — Posted on 2023-06-26

801 Genome reduction occurred in early Prochlorococcus with an unusually low effective population size

Zhang, H.; Hellweger, F. L.; Luo, H.

10.1101/2023.06.25.546417 — genetics — Posted on 2023-06-26

802 Ancient Sheep Genomes reveal four Millennia of North European Short-Tailed Sheep in the Baltic Sea region

Larsson, M. N.; Morell Miranda, P.; Pan, L.; Basak Vural, K.; Kaptan, D.; Rodrigues Soares, A. E.; Kivikero, H.; Kantanen, J.; Somel, M.; Ozer, F.; Johansson, A. M.; Stora, J.; Gunther, T.

10.1101/2023.06.26.544912 — evolutionary biology — Posted on 2023-06-26

803 Alternative reproductive tactics and evolutionary rescue

Knell, R.; Parrett, J.

10.1101/2023.06.26.546260 — evolutionary biology — Posted on 2023-06-26

804 ecode: An R package to investigate community dynamics in ordinary differential equation systems

Wu, H.

10.1101/2023.06.23.546319 — ecology — Posted on 2023-06-26

805 A cytokinetic ring-driven cell rotation achieves Hertwig's rule in early development

Middelkoop, T. C.; Neipel, J.; Cornell, C. E.; Naumann, R.; Pimpale, L. G.; Julicher, F.; Grill, S. W.

10.1101/2023.06.23.546115 — developmental biology — Posted on 2023-06-26

806 A pseudovirus-based method to dynamically mimic SARS-CoV-2-associated cell-to-cell fusion and transmission

Sheng, X.; Yang, Y.; Zhu, F.; Yang, F.; Wang, H.; Hu, R.

10.1101/2023.06.26.546514 — microbiology — Posted on 2023-06-26

807 Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion

Teagle, A. R.; Castro-Sanchez, P.; Brownlie, R. J.; Logan, N.; Kapoor, S. S.; Wright, D.; Salmond, R. J.; Zamoyska, R.

10.1101/2023.06.24.546361 — immunology — Posted on 2023-06-26

808 Rethinking simultaneous suppression in visual cortex via compressive spatiotemporal population receptive fields

Kupers, E. R.; Kim, I.; Grill-spector, K.

10.1101/2023.06.24.546388 — neuroscience — Posted on 2023-06-26

809 A non-oscillatory, millisecond-scale embedding of brain state provides insight into behavior.

Parks, D. F.; Schneider, A. M.; Xu, Y.; Brunwasser, S. J.; Funderburk, S.; Thurber, D.; Blanche, T.; Dyer, E. L.; Haussler, D.; Hengen, K. B.

10.1101/2023.06.09.544399 — neuroscience — Posted on 2023-06-26

810 Multi-night naturalistic cortico-basal recordings reveal mechanisms of NREM slow wave suppression and spontaneous awakenings in Parkinson's disease

Anjum, M. F.; Smyth, C.; Dijk, D.-J.; Starr, P.; Denison, T.; Little, S.

10.1101/2023.06.23.546302 — neuroscience — Posted on 2023-06-26

811 The impact of Subclinical Psychotic Symptoms on Delay and Effort discounting: insights from behavioral, computational, and electrophysiological methods

Terenzi, D.; Silvetti, M.; Zoccolan, G.; Rumiati, R.; Aiello, M.

10.1101/2023.06.24.546371 — neuroscience — Posted on 2023-06-26

812 Repeat investigation during social preference behavior is suppressed in male mice with prefrontal cortex cacna1c (Cav1.2)-deficiency through the dysregulation of neural dynamics

Hackett, J.; Nadkarni, V.; Singh, R. S.; Carthy, C. L.; Antigua, S.; Hall, B. S.; Rajadhyaksha, A. M.

10.1101/2023.06.24.546368 — neuroscience — Posted on 2023-06-26

813 Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity

Bucher, M. L.; Dunn, A. R.; Bradner, J. M.; Egerton, K. S.; Burkett, J. P.; Johnson, M. A.; Miller, G. W.

10.1101/2023.06.26.546143 — neuroscience — Posted on 2023-06-26

814 Fusion Neural Network (FusNet) for predicting protein-mediated loops

Tang, L.; Huang, W.; Hill, M. C.; Ellinor, P. T.; Li, M.

10.1101/2023.06.24.546360 — bioinformatics — Posted on 2023-06-26

815 Catching a wave: on the suitability of traveling-wave solutions in epidemiological modeling

Langmueller, A. M.; Murdock, C. C.; Messer, P. W.

10.1101/2023.06.23.546298 — bioinformatics — Posted on 2023-06-26

816 Maternal choline supplementation: A potential therapy for developmental Manganese exposure?

Howard, S. L.; Beaudin, S. A.; Strupp, B. J.; Smith, D. R.

10.1101/2023.06.23.546356 — animal behavior and cognition — Posted on 2023-06-26

817 Thanks to repetition, dustbathing detection can be automated combining accelerometry and wavelet analysis

Fonseca, R. G.; Flesia, A. G.; Spanevello, F.; de la Fuente, M. V.; Bosch, M. C.; Marin, R. H.; Barberis, L.; Kembro, J. M.

10.1101/2023.06.24.546399 — animal behavior and cognition — Posted on 2023-06-26

818 Intent matters: how flow & forms of information impact collective navigation

Hodgson, T. M.; Johnston, S. T.; Ottobre, M.; Painter, K. J.

10.1101/2023.06.23.545920 — animal behavior and cognition — Posted on 2023-06-26

819 IQCH regulates spermatogenesis by interacting with CaM to promote RNA-binding proteins' expression

Ruan, T.; Zhou, R.; Yang, Y.; Guo, J.; Jiang, C.; Wang, X.; Shen, G.; Dai, S.; Chen, S.; Shen, Y.

10.1101/2023.06.23.546221 — genetics — Posted on 2023-06-26

820 Environmental and genetic influence on rate and spectrum of spontaneous mutations in Escherichia coli

Gifford, D. R.; Bhattacharyya, A.; Geim, A.; Marshall, E.; Krasovec, R.; Knight, C. G.

10.1101/2023.04.06.535897 — evolutionary biology — Posted on 2023-06-26

821 Researcher effects on the biological structure and edaphic conditions of field sites and implications for management.

Rinehart, S. A.; Dybiec, J. M.; Richardson, P.; Walker, J. B.; Peabody, J. D.; Cherry, J. A.

10.1101/2023.06.23.546286 — ecology — Posted on 2023-06-26

822 Transcriptomic profiling of tissue environments critical for post-embryonic patterning and morphogenesis of zebrafish skin

Aman, A. J.; Saunders, L. M.; Carr, A. A.; Srivatsan, S. R.; Eberhard, C.; Carrington, B.; Watkins-Chow, D. E.; Pavan, W.; Trapnell, C.; Parichy, D. M.

10.1101/2021.05.12.443782 — developmental biology — Posted on 2023-06-26

823 The timing of transcription of RpoS-dependent genes varies across multiple stresses in Escherichia coli K-12

Adams, J.; Hoang, J.; Petroni, E.; Ashby, E.; Hardin, J.; Stoebel, D. M.

10.1101/2023.02.17.528066 — microbiology — Posted on 2023-06-26

824 Waste not, want not: Revisiting the analysis that called into question the practice of rarefaction

Schloss, P. D.

10.1101/2023.06.23.546312 — microbiology — Posted on 2023-06-26

825 A Chicken Tapasin ortholog can chaperone empty HLA molecules independently of other peptide-loading components

Papadaki, G. F.; Woodward, C. H.; Young, M. C.; Winters, T. J.; Burslem, G. M.; Sgourakis, N. G.

10.1101/2023.06.23.546255 — immunology — Posted on 2023-06-26

826 Speech recognition from MEG data using covariance filters

Verkhlyutov, V. M.; Vvedensky, V. L.; Gurtovoy, K. G.; Burlakov, E. O.; Martynova, O. V.

10.1101/2023.06.22.546174 — neuroscience — Posted on 2023-06-26

827 The rules of sex and strain: deciphering the chemical language of inbred and wild mouse conspecific scents

Nagel, M.; Niestroj, M.; Bansal, R.; Fleck, D.; Lampert, A.; Stopkova, R.; Stopka, P.; Ben-Shaul, Y.; Spehr, M.

10.1101/2023.06.24.546367 — neuroscience — Posted on 2023-06-26

828 Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis

de la Fuente, D. C.; Tamburini, C.; Stonelake, E.; Griffiths, W. J.; Hall, J.; Owen, M. J.; Linden, D. E. J.; Pocklington, A.; Wang, Y.; Li, M.

10.1101/2023.06.23.546272 — neuroscience — Posted on 2023-06-26

829 Hippocampal sharp-wave ripples correlate with naturally occurring self-generated thoughts in humans

Iwata, T.; Yanagisawa, T.; Ikegaya, Y.; Smallwood, J.; Fukuma, R.; Oshino, S.; Tani, N.; Khoo, H. M.; Kishima, H.

10.1101/2023.06.23.546219 — neuroscience — Posted on 2023-06-26

830 Synapsin E-domain is essential for α-synuclein function

Stavsky, A.; Parra-Rivas, L. A.; Tal, S.; Madhivanan, K.; Roy, S.; Gitler, D.

10.1101/2023.06.24.546170 — neuroscience — Posted on 2023-06-26

831 Mapping neuronal gene expression reveals aspects of ganglionic organization in a gastropod mollusc

Ramirez, M. D.; Bui, T.; Katz, P. S.

10.1101/2023.06.22.546160 — neuroscience — Posted on 2023-06-26

832 An adversarial collaboration to critically evaluate theories of consciousness

10.1101/2023.06.23.546249 — neuroscience — Posted on 2023-06-26

833 Early subcortical response at the fundamental frequency of continuous speech measured with MEG

Schueller, A.; Schilling, A.; Krauss, P.; Reichenbach, T.

10.1101/2023.06.23.546296 — neuroscience — Posted on 2023-06-26

834 Two motor neuron synergies, invariant across ankle joint angles, activate the triceps surae during plantarflexion

Levine, J.; Avrillon, S.; Farina, D.; Hug, F.; Pons, J. L.

10.1101/2022.11.11.516183 — neuroscience — Posted on 2023-06-26

835 The first European woolly rhinoceros mitogenomes retrieved from within cave hyena coprolites suggest long-lasting phylogeographic differentiation

Seeber, P. A.; Palmer, Z.; Schmidt, A.; Chagas, A.; Kitagawa, K.; Marinova-Wolff, E.; Tafelmaier, Y.; Epp, L.

10.1101/2023.06.23.546246 — zoology — Posted on 2023-06-26

836 Effect of Acute Stress on Working Memory in Pilots: Investigating the Modulatory Role of Memory Load

Liang, Y.; Peng, X.; Liu, Y.; Zhu, Q.; Xu, Z.; Yang, J.

10.1101/2023.06.23.546263 — physiology — Posted on 2023-06-26

837 A Computational Model Predicts Sex-specific Responses to Calcium Channel Blockers in Mesenteric Vascular Smooth Muscle

Hernandez Hernandez, G.; O'Dwyer, S. C.; Matsumoto, C.; Tieu, M.; Fong, Z.; Yang, P.-C.; Lewis, T. J.; Santana, L. F.; Clancy, C.

10.1101/2023.06.24.546394 — physiology — Posted on 2023-06-26

838 A co-ordinated transcriptional programme in the maternal liver supplies LC-PUFAs to the conceptus using phospholipids

Amarsi, R.; Furse, S.; Cleaton, M. A.; Maurel, S.; Mitchell, A. L.; Ferguson-Smith, A. C.; Cenac, N.; Williamson, C.; Koulman, A.; Charalambous, M.

10.1101/2023.06.23.546226 — physiology — Posted on 2023-06-26

839 Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

Montecchi, T.; Nannini, G.; De Tommaso, D.; Cassioli, C.; Coppola, F.; Rigressi, M. N.; Carraro, F.; Naldini, A.; Taddei, A.; Marotta, G.; Amedei, A.; Baldari, C. T.; Ulivieri, C.

10.1101/2023.06.23.546212 — cancer biology — Posted on 2023-06-26

840 Acquired Cross-resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC paralogs

10.1101/2023.06.23.546278 — cancer biology — Posted on 2023-06-26

841 Connexin 43 and Cell Culture Substrate Differentially Regulate OCY454 Osteocytic Differentiation and Signaling to Primary Bone Cells

Hoppock, G. A.; Buettmann, E. G.; Denisco, J. A.; Goldscheitter, G. M.; Condyles, S. N.; Juhl, O. J.; Friedman, M. A.; Zhang, Y.; Donahue, H. J.

10.1101/2023.06.23.546276 — cancer biology — Posted on 2023-06-26

842 The presence of a G4 prone sequence upstream of a minimal promoter increases transcriptional activity in the yeast S. cerevisiae

Kratochvilova, L.; Vojsovic, M.; Valkova, N.; Sislerova, L.; El Rashed, Z.; Inga, A.; Monti, P.; Brazda, V.

10.1101/2023.06.23.546269 — cancer biology — Posted on 2023-06-26

843 Assembly of tight junction belts by surface condensation and actin elongation

Sun, D.; Zhao, X.; Wiegand, T.; Bartolucci, G.; Martin-Lemaitre, C.; Grill, S. W.; Hyman, A. A.; Weber, C.; Honigmann, A.

10.1101/2023.06.24.546380 — biophysics — Posted on 2023-06-26

844 Liquid-like condensates mediate competition between actin branching and bundling

Graham, K.; Chandrasekaran, A.; Wang, L.; Yang, N.; Lafer, E. M.; Rangamani, P.; Stachowiak, J. C.

10.1101/2023.06.23.546267 — biophysics — Posted on 2023-06-26

845 Extensible benchmarking of methods that identify and quantify polyadenylation sites from RNA-seq data

Bryce-Smith, S.; Burri, D.; Gazzara, M. R.; Herrmann, C. J.; Danecka, W.; Fitzsimmons, C. M.; Wan, Y. K.; Zhuang, F.; Fansler, M. M.; Fernandez, J. M.; Ferret, M.; Gonzalez-Uriarte, A.; Haynes, S.; Herdman, C.; Kanitz, A.; Katsantoni, M.; Marini, F.; McDonnel, E.; Nicolet, B.; Poon, C.-L.; Rot, G.; Schärfen, L.; Wu, P.-J.; Yoon, Y.; Barash, Y.; Zavolan, M.

10.1101/2023.06.23.546284 — bioinformatics — Posted on 2023-06-26

846 Incorporating physics to overcome data scarcity in predictive modeling of protein function: a case study of BK channels

Nordquist, E.; Zhang, G.; Barethiya, S.; Ji, N.; White, K. W.; Han, L.; Jia, Z.; Shi, J.; Cui, J.; Chen, J.

10.1101/2023.06.24.546384 — bioinformatics — Posted on 2023-06-26

847 Size dependent diffusion and dispersion of particles in mucin

Kumar, P.; Tamayo, J.; Shiu, R.-F.; Chin, W.-C.; Gopinath, A.

10.1101/2023.06.23.546333 — bioengineering — Posted on 2023-06-26

848 Metabolic engineering of Corynebacterium glutamicum for the production of anthranilate from glucose and xylose

Mutz, M.; Bruening, V.; Bruesseler, C.; Mueller, M.-F.; Noack, S.; Marienhagen, J.

10.1101/2023.06.24.546385 — bioengineering — Posted on 2023-06-26

849 Biomimetic Artificial Bone Marrow Niches for the Scale Up of Hematopoietic Stem Cells

Bosch-Fortea, M.; Marciano, D.; Gautrot, J.

10.1101/2023.06.23.546233 — bioengineering — Posted on 2023-06-26

850 Solitary Silence and Social Sounds: Music influences mental imagery, inducing thoughts of social interactions

Herff, S. A.; Cecchetti, G.; Ericson, P.; Cano, E.

10.1101/2023.06.22.546175 — animal behavior and cognition — Posted on 2023-06-26

851 Familiarity-taxis: A bilateral approach to view-based navigation.

Steinbeck, F.; Kagioulis, S.; Dewar, A.; Philippides, A.; Nowotny, T.; Graham, P.

10.1101/2023.06.23.546247 — animal behavior and cognition — Posted on 2023-06-26

852 A fast, reproducible, high-throughput variant calling workflow for evolutionary, ecological, and conservation genomics

Mirchandani, C. D.; Shultz, A. J.; Thomas, G. W.; Smith, S. J.; Baylis, M.; Arnold, B.; Corbett-Detig, R.; Enbody, E.; Sackton, T. B.

10.1101/2023.06.22.546168 — genomics — Posted on 2023-06-26

853 Dark side of the honeymoon: reconstructing the Asian x European rose breeding history through the lens of genomics

Leroy, T.; Albert, E.; Thouroude, T.; Baudino, S.; Caissard, J.-C.; Chastellier, A.; Chameau, J.; Jeauffre, J.; Loubert, T.; Paramita, S. N.; Pernet, A.; Soufflet-Freslon, V.; Oghina-Pavie, C.; Foucher, F.; Oyant, L. H.-S.; Clotault, J.

10.1101/2023.06.22.546162 — genomics — Posted on 2023-06-26

854 Improving accuracy and precision of heritability estimation in twin studies: Reassessing the measurement error assumption

Chen, G.; Moraczewski, D.; Taylor, P. A.

10.1101/2023.06.24.546389 — genetics — Posted on 2023-06-26

855 The haplolethal gene wupA of Drosophila exhibits potential as a target for an X-poisoning gene drive

Lawler, C. D.; Hernandes, N.; Parra Nunez, A. K.; Bhide, S.; Baxter, S.; Robin, C.

10.1101/2023.06.23.546292 — genetics — Posted on 2023-06-26

856 Field phenomics reveals genetic variation for transpiration response to vapor pressure deficit in sorghum

Raymundo, R.; Wang, X.; Felderhoff, T.; Sexton, S.; poland, j.; Lipka, A.; Morris, G.

10.1101/2023.06.23.546345 — genetics — Posted on 2023-06-26

857 Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition

Gao, C. W.; Lin, W.; Riddle, R. C.; Kushwaha, P.; Boukas, L.; Bjornsson, H. T.; Hansen, K. D.; Fahrner, J. A.

10.1101/2023.06.23.546270 — genetics — Posted on 2023-06-26

858 A multi-layered integrative analysis reveals a cholesterol metabolic program in outer radial glia with implications for human brain evolution

Moriano, J.; Leonardi, O.; Vitriolo, A.; Testa, G.; Boeckx, C.

10.1101/2023.06.23.546307 — evolutionary biology — Posted on 2023-06-26

859 rphylopic: An R package for fetching, transforming, and visualising PhyloPic silhouettes

Gearty, W.; Jones, L. A.

10.1101/2023.06.22.546191 — evolutionary biology — Posted on 2023-06-26

860 Locomotor effects of a fibrosis-based immune response in stickleback fish

Matthews, D. G.; Maciejewski, M. F.; Wong, G. A.; Lauder, G. V.; Bolnick, D. I.

10.1101/2023.06.24.546342 — evolutionary biology — Posted on 2023-06-26

861 Climate and land use change variables affect microbial assemblage and denitrification capability in organic-rich subterranean estuaries

Adyasari, D.; Dimova, N. T.; Ni Chadhain, S.; Waska, H.

10.1101/2023.06.23.546288 — ecology — Posted on 2023-06-26

862 Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice

Moutard, L.; Goudin, C.; Jaeger, C.; Duparc, C.; Louiset, E.; Pereira, T.; Fraissinet, F.; Delessard, M.; Saulnier, J.; Rives-Feraille, A.; Delalande, C.; Lefebvre, H.; Rives, N.; Dumont, L.; Rondanino, C.

10.1101/2022.11.18.517042 — developmental biology — Posted on 2023-06-26

863 Closed-loop optogenetic perturbation of macaque oculomotor cerebellum: evidence for an internal saccade model

Soetedjo, R.; Horwitz, G.

10.1101/2023.06.22.546199 — neuroscience — Posted on 2023-06-26

864 The speed and phase of locomotion dictate saccade probability and simultaneous low-frequency power spectra

Davidson, M. J.; Barnes, L.; Alais, D. J.

10.1101/2023.06.22.546202 — neuroscience — Posted on 2023-06-26

865 Not alpha power: prestimulus beta power predicts the magnitude of individual temporal order bias for audiovisual stimuli

Jiang, Z.; Wang, L.; An, X.; Liu, S.; Yin, E.; Yan, Y.; Ming, D.

10.1101/2023.06.23.546349 — neuroscience — Posted on 2023-06-26

866 Cognitive Model Discovery via Disentangled RNNs

Miller, K. J.; Eckstein, M.; Botvinick, M. M.; Kurth-Nelson, Z.

10.1101/2023.06.23.546250 — neuroscience — Posted on 2023-06-26

867 Present: flexible neuroscience- and technology-driven frameworks for the study of classroom engagement

Shatto, C. L.; Thorpe, J. N.; Friedman, J. S.; Rosario, I. E.; Gu, Z.; Shi, J.; Zhuo, M.; Brown, A.; He, X.; Spagna, A.

10.1101/2023.06.23.544732 — neuroscience — Posted on 2023-06-26

868 Converging on consistent functional connectomics

Luppi, A. I.; Gellersen, H. M.; Liu, Z.-Q. I.; Peattie, A. R. D.; Manktelow, A. E.; Adapa, R.; Owen, A. M.; Naci, L.; Menon, D.; Dimitriadis, S. I.; Stamatakis, E. A.

10.1101/2023.06.23.546329 — neuroscience — Posted on 2023-06-26

869 The metabolic role of vitamin D in children's neurodevelopment: a network study

De Marzio, M.; Lasky-Su, J.; Chu, S. H.; Prince, N.; Litonjua, A. A.; Weiss, S. T.; Kelly, R. S.; Glass, K. R.

10.1101/2023.06.23.546277 — systems biology — Posted on 2023-06-26

870 Divergent iron-regulatory states contribute to heterogeneity in breast cancer aggressiveness

Leineweber, W.; Khalilimeybodi, A.; Rangamani, P.; Fraley, S. I.

10.1101/2023.06.23.546216 — cancer biology — Posted on 2023-06-26

871 The Physical Effects of Learning

Stern, M.; Liu, A. J.; Balasubramanian, V.

10.1101/2023.06.23.546243 — biophysics — Posted on 2023-06-26

872 ATOMDANCE: machine learning denoising and resonance analysis for functional and evolutionary comparisons of protein dynamics

Babbitt, G. A.; Rajendran, M.; Lynch, M. L.; Asare-Bediako, R.; Mouli, L. T.; Ryan, C. J.; Srivastava, H.; Phadke, K.; Reed, M. L.; Moore, N.; Ferran, M. C.; Fokoue, E. P.

10.1101/2023.04.20.537698 — biophysics — Posted on 2023-06-26

873 A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint

Sanchez, H.; Liu, Z.; van Veen, E.; van Laar, T.; Solano, B.; Diffley, J. F. X.; Dekker, N. H.

10.1101/2023.05.18.541303 — biophysics — Posted on 2023-06-26

874 Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension

Karnam, S.; Maurya, S.; Ng, E.; Choudhary, A.; Thobani, A.; Flanagan, J. G.; Gronert, K.

10.1101/2023.06.22.546157 — neuroscience — Posted on 2023-06-26

875 Genome-scale metabolic model predicts mechanistic differences in metabolic gradient of spatially resolved small intestine villi

Lim, J. J.; Cui, J. Y.; Wang, Y.

10.1101/2023.06.22.546161 — bioinformatics — Posted on 2023-06-26

876 Bruno 1 regulates cytoskeleton dynamics and a temporal splicing transition to promote myofibril assembly, growth and maturation in Drosophila flight muscle

Nikonova, E.; Canela Grimau, M.; Barz, C.; Esser, A.; Bouterwek, J.; Roy, A.; Gensler, H.; Hess, M.; Straub, T.; Forne, I.; Spletter, M. L.

10.1101/2023.06.24.546382 — developmental biology — Posted on 2023-06-26

877 Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

White, J. S.; Su, J. J.; Ruark, E. M.; Hua, J.; Hutson, M. S.; Page-McCaw, A.

10.1101/2023.06.25.546442 — cell biology — Posted on 2023-06-26

878 A FRET-based excitatory luminopsin with improved efficacy of bioluminescence-driven activation

Bjorefeldt, A.; Murphy, J.; Crespo, E. L.; Prakash, M.; Friedman, N.; Brown, T. M.; Lipscombe, D.; Moore, C. I.; Hochgeschwender, U.; Shaner, N. C.

10.1101/2023.06.26.545546 — neuroscience — Posted on 2023-06-26

879 Tessellation Of Artificial Touch Via Microstimulation Of Human Somatosensory Cortex

Greenspon, C. M.; Shelchkova, N. D.; Valle, G.; Hobbs, T.; Berger-Wolf, E. I.; Hutchison, B. C.; Dogruoz, E.; Jordan, P. M.; Verbarschott, C.; Callier, T.; Sobinov, A.; Okorokova, E. V.; Prasad, D.; He, Q.; Liu, F.; Miller, J. P.; Lee, R. C.; Satzer, D.; Gonzalez-Martinez, J.; Warnke, P.; Miller, L. E.; Boninger, M. L.; Ajiboye, B. B.; Graczyk, E. L.; Downey, J. E.; Collinger, J.; Hatsopoulos, N.; Gaunt, R.; Bensmaia, S. J.

10.1101/2023.06.23.545425 — neuroscience — Posted on 2023-06-26

880 Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons

Wang, H.; Chen, R.; Xiao, L.; Kumar, M.; Acevedo-Cintron, J.; Siuda, J.; Koziorowski, D.; Wszolek, Z. K.; Dawson, V. L.; Dawson, T.

10.1101/2023.06.23.546087 — neuroscience — Posted on 2023-06-26

881 High performers demonstrate greater neural synchrony than low performers across behavioral domains

Chamberlain, T. A.; Corriveau, A.; Song, H.; Kwon, Y. H.; Yoo, K.; Chun, M.; Rosenberg, M. D.

10.1101/2023.06.22.546173 — neuroscience — Posted on 2023-06-26

882 Synaptic and dendritic architecture of two types of hippocampal somatostatin interneurons

Takacs, V.; Bardoczi, Z.; Orosz, A.; Major, A.; Tar, L.; Berki, P.; Papp, P.; Mayer, M. I.; Zsolt, L.; Sos, K. E.; Kali, S.; Freund, T. F.; Nyiri, G.

10.1101/2023.05.14.540675 — neuroscience — Posted on 2023-06-26

883 New genetic tools for mushroom body output neurons in Drosophila

Rubin, G. M.; Aso, Y.

10.1101/2023.06.23.546330 — neuroscience — Posted on 2023-06-26

884 Sex-dependent impairments of parvalbumin expressing neurons in the retrosplenial cortex in Alzheimer's disease

Terstege, D. J.; Ren, Y.; Sargin, D.; Epp, J. R.

10.1101/2023.06.22.546142 — neuroscience — Posted on 2023-06-26

885 SnakeFace: a transfer learning based app for snake classification

Pires, J. G.; Dias Braga, L. H.

10.1101/2023.06.13.544741 — bioinformatics — Posted on 2023-06-26

886 Assessing the performance of the Cell Painting assay across different imaging systems

Tromans-Coia, C.; Jamali, N.; Abbasi, H. S.; Giuliano, K. A.; Hagimoto, M.; Jan, K.; Kaneko, E.; Letzsch, S.; Schreiner, A.; Sexton, J. Z.; Suzuki, M.; Trask, O. J.; Yamaguchi, M.; Yanagawa, F.; Yang, M.; Carpenter, A. E.; Cimini, B. A.

10.1101/2023.02.15.528711 — cell biology — Posted on 2023-06-26

887 Differentiation of gram-negative intermembrane phospholipid transporter function by fatty acid saturation preference

Rai, A. K.; Sawasato, K.; Kozlova, A.; Sparagna, G. C.; Bogdanov, M. V.; Mitchell, A. M.

10.1101/2023.06.21.545913 — microbiology — Posted on 2023-06-26

888 Microeukaryotic predators shape the wastewater microbiome.

Heck, N.; Freudenthal, J.; Dumack, K.

10.1101/2023.04.04.535543 — microbiology — Posted on 2023-06-26

889 Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level

Yamaguchi, A.; Maeshige, N.; Noguchi, H.; Yan, J.; Ma, X.; Uemura, M.; Kondo, H.; Sarosiek, K.; Fujino, H.

10.1101/2023.06.14.544906 — immunology — Posted on 2023-06-26

890 OneOPES, a combined enhanced sampling method to rule them all

Rizzi, V.; Aureli, S.; Ansari, N.; Gervasio, F. L.

10.1101/2023.03.06.531337 — biophysics — Posted on 2023-06-26

891 Neural Basis Of Sound-Symbolic Pseudoword-Shape Correspondences

Barany, D. A.; Lacey, S.; Matthews, K. L.; Nygaard, L. C.; Sathian, K.

10.1101/2023.04.14.536865 — neuroscience — Posted on 2023-06-26

892 The RNA-DNA world and the emergence of DNA-encoded heritable traits

Roy, S.; Sengupta, S.

10.1101/2023.03.14.532532 — evolutionary biology — Posted on 2023-06-26

893 Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer

Wortmann, E.; Osswald, A.; Wylensek, D.; Liang, W.; Treichel, N.; Schumacher, F.; Volet, C.; Matysik, S.; Kleigrewe, K.; Gigl, M.; Rohn, S.; Kleuser, B.; Liebisch, G.; Bernier-Latmani, R.; Schnieke, A.; Flisikowski, K.; Ocvirk, S.; Clavel, T.

10.1101/2023.03.17.533140 — microbiology — Posted on 2023-06-26

894 Updated phylogeny and protein structure predictions revise the hypothesis on the origin of MADS-box transcription factors in land plants

Qiu, Y.; Li, Z.; Walther, D.; Köhler, C.

10.1101/2023.01.10.523452 — plant biology — Posted on 2023-06-26

895 Modelling collagen fibril self-assembly from extracellular medium in embryonic tendon

Revell, C. K.; Herrera, J. A.; Lawless, C.; Lu, Y.; Kadler, K. E.; Chang, J.; Jensen, O. E.

10.1101/2023.03.13.532430 — biophysics — Posted on 2023-06-26

896 SAMBA: Structure-Learning of Aquaculture Microbiomes Using a Bayesian Approach

Soriano, B.; Hafez, A.; Naya-Catala, F.; Moldovan, R. A.; Toxqui-Rodriguez, S.; Piazzon, M. C.; Arnau, V.; Llorens, C.; Perez-Sanchez, J.

10.1101/2022.12.30.522281 — bioinformatics — Posted on 2023-06-26

897 Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting

Wei, J.; Lotfy, P.; Faizi, K.; Baungaard, S.; Gibson, E.; Wang, E.; Slabodkin, H.; Kinnaman, E.; Chandrasekaran, S.; Kitano, H.; Durrant, M. G.; Duffy, C. V.; Hsu, P. D.; Konermann, S.

10.1101/2021.09.14.460134 — bioengineering — Posted on 2023-06-26

898 Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan

Nordin, K.; Pedersen, R.; Falahati, F.; Johansson, J.; Grill, F.; Andersson, M.; Korkki, S. M.; Backman, L.; Zalesky, A.; Rieckmann, A.; Nyberg, L.; Salami, A.

10.1101/2023.03.24.534115 — neuroscience — Posted on 2023-06-26

899 Calibration of Agent Based Models for Monophasic and Biphasic Tumour Growth using Approximate Bayesian Computation

Wang, X.; Jenner, A. L.; Warne, D. J.; Salomone, R.; Drovandi, C.

10.1101/2022.09.13.507714 — systems biology — Posted on 2023-06-26

900 Yeast PRPP amidotransferase assembles into fine granules to promote de novo purine synthesis through intermolecular substrate channeling

Takaine, M.; Morita, R.

10.1101/2023.06.05.543815 — cell biology — Posted on 2023-06-26

901 Manipulating mitochondrial dynamics in the NTS prevents diet-induced deficits in brown fat morphology and glucose uptake

Fozzato, A.; New, L. E.; Griffiths, J. C.; Patel, B.; Deuchars, S. A.; Filippi, B. M.

10.1101/2023.01.04.522581 — neuroscience — Posted on 2023-06-26

902 The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes

Ullrich, S.; Leidescher, S.; Feodorova, Y.; Thanisch, K.; Fini, J.-B.; Kaspers, B.; Weber, F.; Markova, B.; Fuehrer, D.; Romitti, M.; Krebs, S.; Blum, H.; Leonhardt, H.; Costagliola, S.; Heuer, H.; Solovei, I.

10.1101/2023.06.23.546241 — cell biology — Posted on 2023-06-26

903 GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis

Gobbo, F.; Zingariello, M.; Verachi, P.; Falchi, M.; Arciprete, F.; Martelli, F.; Peli, A.; Mazzarini, M.; Vierstra, J.; Mead-Harvey, C.; Dueck, A. C.; Sarli, G.; Nava, S.; Sgalla, G.; Richeldi, L.; Migliaccio, A. R.

10.1101/2023.06.20.542249 — immunology — Posted on 2023-06-26

904 Folate receptor overexpression shortens C. elegans lifespan by impeding adaptation to microbial metabolism

Shrestha, B.; Tallila, M.; Matilainen, O.

10.1101/2023.06.26.546484 — genetics — Posted on 2023-06-26

905 Vacuolar H+-ATPase Determines Daughter Cell Fates through Asymmetric Segregation of the Nucleosome Remodeling and Deacetylase Complex

Xie, Z.; Chai, Y.; Zhu, Z.; Shen, Z.; Zhao, Z.; Xiao, L.; Du, Z.; Ou, G.; Li, W.

10.1101/2023.06.25.546476 — cell biology — Posted on 2023-06-26

906 Glucose-stimulated KIF5B-driven microtubule sliding organizes microtubule networks in pancreatic beta cells

Bracey, K.; Noguchi, P.; Edwards, C.; Cario, A.; Gu, G.; Kaverina, I.

10.1101/2023.06.25.546468 — cell biology — Posted on 2023-06-26

907 Specific prostaglandins are produced in the migratory cells and the surrounding substrate to promote Drosophila border cell migration

Mellentine, S. Q.; Ramsey, A. S.; Li, J.; Brown, H. N.; Tootle, T.

10.1101/2023.06.23.546291 — cell biology — Posted on 2023-06-26

908 Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen sensing pathways in mammalian cells

Tian, Y.-M.; Holdship, P.; To, T. Q.; Ratcliffe, P. J.; Keeley, T. P.

10.1101/2023.06.25.545688 — cell biology — Posted on 2023-06-26

909 TOMM40 and TOMM22 of the Translocase Outer Mitochondrial Membrane Complex rescue statin-impaired mitochondrial dynamics, morphology, and mitophagy in skeletal myotubes

Yang, N. V.; Rogers, S.; Guerra, R.; Pagliarini, D. J.; Theusch, E.; Krauss, R. M.

10.1101/2023.06.24.546411 — cell biology — Posted on 2023-06-26

910 Differences in Hepatocellular Iron Metabolism Underlie Sexual Dimorphism in Hepatocyte Ferroptosis

Tao, H.; Dar, H. Y.; Tian, C.; Banerjee, S.; Glazer, E. S.; Srinivasan, S.; Zhu, L.; Pacifici, R.; He, P.

10.1101/2023.06.24.546395 — cell biology — Posted on 2023-06-26

911 Study on Vibrational Behavior of Cytoskeletons Modeled by Cylindrical Tensegrity Structure

Nouchi, E.; Oka, T.; Kataoka, N.; Kawano, Y.; Gan, B. S.

10.1101/2023.06.23.546353 — cell biology — Posted on 2023-06-26

912 PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities

Đukic, N.; Stromland, O.; Munnur, D.; Zhu, K.; Schuller, M.; Chatrin, C.; Kar, P.; Rack, J. G. M.; Baretic, D.; Schüler, H.; Wijngaarden, S.; Filippov, D. V.; Sanyal, S.; Smith, R.; Ahel, D.; Ahel, I.

10.1101/2023.06.25.546318 — cell biology — Posted on 2023-06-26

913 Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals

Crapart, C.; Scott, Z. C.; Konno, T.; Sharma, A.; Bailey, D. M.; Avezov, E.; Koslover, E. F.

10.1101/2023.06.23.546357 — cell biology — Posted on 2023-06-26

914 TECPR1 provides E3-ligase like activity to the ATG5-ATG12 complex to conjugate LC3/ATG8 to damaged lysosomes

Wang, Y.; Jefferson, M.; Mccoll, J.; Verkade, P.; Mayer, U.; Wileman, T.

10.1101/2023.06.24.546289 — cell biology — Posted on 2023-06-26

915 Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

Waite, K. A.; Vontz, G.; Lee, S. Y.; Roelofs, J.

10.1101/2023.06.25.546446 — cell biology — Posted on 2023-06-26

916 Histone chaperone HIRA, Promyelocytic Leukemia (PML) protein and p62/SQSTM1 coordinate to regulate inflammation during cell senescence and aging.

Dasgupta, N.; Lei, X.; Arnold, R.; Teneche, M. G.; Miller, K. N.; Rajesh, A.; Davis, A.; Anschau, V.; Campos, A. R.; Gilson, R.; Havas, A.; Yin, S.; Chua, Z. M.; Proulx, J.; Alcaraz, M.; Rather, M. I.; Baeza, J.; Schultz, D. C.; Berger, S. L.; Adams, P. D.

10.1101/2023.06.24.546372 — cell biology — Posted on 2023-06-26

917 Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation

Bragg, R. M.; Coffey, S. R.; Cantle, J. P.; Hu, S.; Singh, S.; Legg, S. R. W.; McHugh, C. A.; Toor, A.; Zeitlin, S. O.; Kwak, S.; Howland, D.; Vogt, T. F.; Monga, S. P.; Carroll, J. B.

10.1101/2023.06.24.546334 — cell biology — Posted on 2023-06-26

918 Hypoxia induced oxidative stress and endoplasmic reticulum stress promoted myocardial cell fibrosis

guang, x.; jiang, z.; chun, z.

10.1101/2023.06.24.546381 — cell biology — Posted on 2023-06-26

919 Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry

Shaw, A. B.; Tse, H. N.; Byford, O.; plahe, g.; Moon-Walker, A.; Saphire, E. O.; Whelan, S. P. J.; Mankouri, J.; Fontana, J.; Barr, J. N.

10.1101/2023.06.23.546275 — cell biology — Posted on 2023-06-26

920 Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

Spiga, L.; Fansler, R. T.; Perera, Y. R.; Shealy, N. G.; Munneke, M. J.; Torres, T. P.; David, H.; Lemoff, A.; Ran, X.; Richardson, K. L.; Pudlo, N.; Martens, E. C.; Yang, Z. J.; Skaar, E. P.; Byndloss, M. X.; Chazin, W. J.; Zhu, W.

10.1101/2023.06.25.546471 — microbiology — Posted on 2023-06-26

921 State-of-the-art image and video quality assessment with a metric based on an intrinsically nonlinear neural summation model

Luna, R.; Zabaleta, I.; Bertalmio, M.

10.1101/2022.12.22.521587 — neuroscience — Posted on 2023-06-26

922 ArcheD, a residual neural network for prediction of cerebrospinal fluid amyloid-beta from amyloid PET images

Tagmazian, A. A.; Schwarz, C.; Lange, C.; Pitkanen, E.; Vuoksimaa, E.; for the Alzheimer's Disease Neuroimaging Initiative,

10.1101/2023.06.20.545686 — neuroscience — Posted on 2023-06-26

923 RTEL1 is required for silencing and epigenome stability

Olivier, M.; Hesketh, A.; Pouch-Pelissier, M.-N.; Pelissier, T.; Huang, Y.; Latrasse, D.; Benhamed, M.; Mathieu, O.

10.1101/2023.04.11.535823 — genomics — Posted on 2023-06-26

924 Experience replay facilitates the formation of the hexagonal pattern of grid cells

Zhang, B.; Ma, L.; Liu, J.

10.1101/2023.02.19.529130 — neuroscience — Posted on 2023-06-25

925 The microenvironment dictates glycocalyx construction and immune surveillance

Tharp, K.; Park, S.; Timblin, G. A.; Richards, A.; Berg, J.; Twells, N.; Riley, N. M.; Peltan, E.; Shon, D. J.; Stevenson, E.; Tsui, C. K.; Palomba, F.; Lefebvre, A. E.; Soens, R.; Ayad, N.; ten Hoeve-Scott, J.; Healy, K.; Digman, M.; Dillin, A.; Bertozzi, C.; Mahal, L. K.; Swaney, D.; Cantor, J. R.; Paszek, M.; Weaver, V.

10.1101/2023.06.23.546317 — cell biology — Posted on 2023-06-25

926 Sleep-insomnia superposition: opposing brain signatures of sleep in task-based and resting-state conditions

Abdelhack, M.; Zhukovsky, P.; Milic, M.; Harita, S.; Wainberg, M.; Tripathy, S. J.; Griffiths, J. D.; Hill, S. L.; Felsky, D.

10.1101/2023.05.13.540646 — neuroscience — Posted on 2023-06-25

927 Pellioditis pelhami n. sp. (Nematoda: Rhabditidae) and Pellioditis pellio (Schneider, 1866), earthworm associates from different subclades within Pellioditis (syn. Phasmarhabditis Andrassy, 1976)

Tandingan De Ley, I.; Kiontke, K.; Bert, W.; Sudhaus, W.; Fitch, D. H. A.

10.1101/2023.06.22.546148 — zoology — Posted on 2023-06-25

928 Early divergence and gene exchange highways in the evolutionary history of Mesoaciditogales

Farrell, A. A.; Nesbo, C. L.; Zhaxybayeva, O.

10.1101/2023.06.22.546130 — evolutionary biology — Posted on 2023-06-25

929 IRF8 configures enhancer landscape in postnatal microglia and directs microglia specific transcriptional programs

Saeki, K.; Pan, R.; Lee, E.; Kurotaki, D.; Ozato, K.

10.1101/2023.06.25.546453 — immunology — Posted on 2023-06-25

930 Parkinsons Disease Pathology is Directly Correlated to SIRT3 in Human Subjects and Animal Models: Implications for AAV.SIRT3-myc as a Disease-Modifying Therapy.

Trinh, D.; Israwi, A.; Brah, H.; Arriola-Villafue, J.; Volpicelli-Daley, L.; Nash, ; Nash, J. E.

10.1101/2023.06.23.546104 — neuroscience — Posted on 2023-06-25

931 Single cell transcriptomics unveiled that early life BDE-99 exposure reprogrammed the gut-liver axis to promote a pro-inflammatory metabolic signature in male mice at late adulthood

Lim, J. J.; Goedkin, M.; Jin, Y.; Gu, H.; Cui, J. Y.

10.1101/2023.06.22.546158 — pharmacology and toxicology — Posted on 2023-06-25

932 Assessment of diseases and insect pests of apple (Malus domestica Borkh) in Silte Zone, Southern Ethiopia

Shega, S. W.; Aloto, A. A.; Adimasu Adinew Aloto,

10.1101/2023.06.22.546144 — pathology — Posted on 2023-06-25

933 Adhesion energy controls lipid binding-mediated endocytosis

Groza, R.; Schmidt, K. V.; Muller, P. M.; Ronchi, P.; Schlack-Leigers, C.; Neu, U.; Puchkov, D.; Dimova, R.; Matthaus, C.; Taraska, J. W.; Weikl, T.; Ewers, H.

10.1101/2023.06.23.546235 — biophysics — Posted on 2023-06-25

934 Antimicrobial Evaluation of Salvadora persica Methanolic Stem Extract and In vivo Modelling of its Identified Constituting Compounds Revealed Antibacterial Effect of 2--4-morpholino-6-(1-pyrrolidinyl)-1,3,5-triazine in the Treatment of Dental Plague

Adigun, T. O.; Maikarfi, M.; Abdulhameed, O. A.; Fagboro, O. O.; Oyebamiji, S. O.; Akinsehinwa, S. A.

10.1101/2023.06.25.546444 — biochemistry — Posted on 2023-06-25

935 Intrinsically Disordered Regions Promote Protein Refoldability and Facilitate Retrieval from Biomolecular Condensates

To, P.; Bhagwat, A. M.; Tarbox, H. E.; Ecer, A.; Wendorff, H.; Jamieson, Z.; Trcek, T.; Fried, S. D.

10.1101/2023.06.25.546465 — biochemistry — Posted on 2023-06-25

936 The VEGF G-quadruplex forming promoter is repaired via long-patch BER

Hussen, A.; Kravitz, H. L.; Freudenthal, B. D.; Whitaker, A. M.

10.1101/2023.06.25.546439 — biochemistry — Posted on 2023-06-25

937 The effect of circulation rate on the water quality of container-type recirculation aquaculture system under different feeding rates of Schizothorax wangchiachii

Zhou, J.; Cai, Q.; Zhou, K.

10.1101/2023.06.22.546147 — animal behavior and cognition — Posted on 2023-06-25

938 Integrated multi-approaches reveal unique metabolic mechanisms of Vestimentifera to adapt to deep-sea hydrothermal vents

Sun, Q.; Yuan, Z.; Sun, Y.; Sun, L.

10.1101/2023.06.25.546427 — genomics — Posted on 2023-06-25

939 The platyrrhine primate Cebus imitator uses gaze to adjust grasp posture for food handling and withdraw to the mouth

Whishaw, I. Q.; Mah, M.; Casorso, J. G.; Chacon, E. M.; Chalk-Wilayto, J.; Laird, M.; Melin, A.

10.1101/2023.06.22.546193 — evolutionary biology — Posted on 2023-06-25

940 Piezo1 conspires with INF2 to promote amoeboid migration in confined environments

Neelakshi, K.; Caruso, A. P.; Prokopiou, N.; Logue, J. S.

10.1101/2023.06.23.546346 — cell biology — Posted on 2023-06-25

941 Generation of a robust reference gut microbiome dataset for an urban population in Argentina optimized by a machine learning approach

Rohr, C.; Sciara, M.; Brun, B.; Fay, F.; vazquez, m.

10.1101/2023.06.24.546376 — microbiology — Posted on 2023-06-25

942 Metabolic adaptations and aquifer connectivity underpin the high productivity rates in the relict subsurface water

Atencio, B.; Geisler, E.; Rubin Blum, M.; Bar-Zeev, E.; Adar, E. M.; Ram, R.; Ronen, Z.

10.1101/2023.06.25.546375 — microbiology — Posted on 2023-06-25

943 Mechanistic basis for nigericin-induced NLRP1 inflammasome activation in human epithelial cells

Zhong, F. L.; Rozario, P.; Pinilla, M.; Vind, A. C.; Robinson, K.; Gee Ann, T.; Jasrie Firdaus, M.; Francisco Martinez, J.; Zhewang, L.; Bekker-Jensen, S.; Meunier, E.

10.1101/2023.06.23.546021 — immunology — Posted on 2023-06-25

944 Intrarenal myeloid subsets associated with kidney injury are comparable in mice and patients with lupus nephritis

Hoover, P.; Lieb, D. J.; Kang, J.; Li, S.; Peters, M.; Raparia, C.; Arazi, A.; Eisenhaure, T.; Gurajala, S. S.; Xiao, Q.; Mishra, R.; Spurrell, M.; Menon, R.; Kretzler, M.; Chen, J.; Nieman, L.; Sonny, A.; Demeke, D.; Hodgin, J.; Guthridge, J.; Fava, A.; Clancy, R.; Putterman, C.; Izmirly, P.; Belmont, H. M.; Kalunian, K.; Kamen, D.; Wofsy, D.; Buyon, J.; James, J. A.; Petri, M.; Diamond, B.; Raychaudhuri, S.; The Kidney Precision Medicine Project, ; The Accelerating Medicines Partnership: RA/SLE network, ; Hacohen, N.; Davidson, A.

10.1101/2023.06.24.546409 — immunology — Posted on 2023-06-25

945 Targeting the Microbiome to Improve Gut Health and Breathing Function After Spinal Cord Injury

Wilson, J. N.; Kigerl, K. A.; Sunshine, M. D.; Taylor, C. E.; Speed, S. L.; Rose, B. C.; Calulot, C. M.; Dong, B. E.; Hawkinson, T. R.; Clarke, H. A.; Bachstetter, A. D.; Waters, C. M.; Sun, R. C.; Popovich, P. G.; Alilain, W. J.

10.1101/2023.06.23.546264 — neuroscience — Posted on 2023-06-25

946 Cilia loss on distinct neuron populations differentially alters cocaine-induced locomotion and reward

Everett, T.; Ten Ecyk, T. W.; Wu, C.-H.; Shelowitz, A. L.; Stansbury, S. M.; Firek, A.; Setlow, B.; McIntyre, J. C.

10.1101/2023.06.22.546096 — neuroscience — Posted on 2023-06-25

947 Manipulation of encapsulated artificial phospholipid membranes using sub-micellar lysolipid concentrations.

Dimitriou, P.; Li, J.; Jamieson, W. D.; Schneider, J. J.; Castell, O.; Barrow, D.

10.1101/2023.06.25.546396 — synthetic biology — Posted on 2023-06-25

948 Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation.

Radvanyi, Z.; Yoo, E. J.; Kandasamy, P.; Salas-Bastos, A.; Monnerat, S.; Refardt, J.; Christ-Crain, M.; Hayashi, H.; Kondo, Y.; Jantsch, J.; Rubio-Aliaga, I.; Sommer, L.; Wagner, C. A.; Hediger, M. A.; Kwon, H. M.; Loffing, J.; Pathare, G.

10.1101/2023.06.23.546282 — physiology — Posted on 2023-06-25

949 Alterations in Cardiovascular and Cerebral Pulse Wave Velocity in 5XFAD Murine Model of Alzheimer's Disease

Marshall, A. G.; Neikirk, K.; Barongan, T.; Shao, B.; Crabtree, A.; Stephens, D. C.; Vue, Z.; Beasley, H. K.; Garza-Lopez, E.; Scudese, E.; Damo, S. M.; Gomez, J. A.; Taffet, G.; Hinton, A.; Reddy, A. K.

10.1101/2023.06.22.546154 — physiology — Posted on 2023-06-25

950 Targeting mitophagy in SRSF2 mutant hematologic malignancies

Liu, X.; Devadiga, S. A.; Stanley, R. F.; Moroow, R.; Janssen, K.; Quesnel-Vallieres, M.; Pomp, O.; Moverley, A. A.; Li, C.; Skuli, N.; Carroll, M. P.; Huang, J.; Wallace, D. C.; Lynch, K. W.; Abdel-Wahab, O.; Klein, P. S.

10.1101/2023.06.25.546449 — cancer biology — Posted on 2023-06-25

951 Dynamic ParB-DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

Tisma, M.; Janissen, R.; Antar, H.; Martin Gonzalez, A.; Barth, R.; Beekman, T.; van der Torre, J.; Michieletto, D.; Gruber, S.; Dekker, C.

10.1101/2023.06.25.546419 — biophysics — Posted on 2023-06-25

952 Fluorogenesis: Inducing Fluorescence in a Non-Fluorescent Protein Through Photoinduced Chromophore Transfer of a Genetically Encoded Chromophore

Kumar, Y.; Singh, R. K.; Ojha, M.; Pushpavanam, K.

10.1101/2023.06.24.546416 — biochemistry — Posted on 2023-06-25

953 Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus MT:10398A>G

Smullen, M.; Olson, M. N.; Murray, L. F.; Suresh, M.; Yan, G.; Dawes, P.; Barton, N. J.; Mason, J. N.; Zhang, Y.; Fernandez-Fontaine, A. A.; Church, G. M.; Mastroeni, D.; Wang, Q.; Lim, E. T.; Chan, Y.; Readhead, B.

10.1101/2023.06.22.546129 — genomics — Posted on 2023-06-25

954 Deletion of a conserved genomic region associated with adolescent idiopathic scoliosis leads to vertebral rotation in mice.

McCallum-Loudeac, J.; Moody, E.; Johnstone, G.; Sircombe, K.; Clarkson, A. N.; Wilson, M. J.

10.1101/2023.06.22.546196 — genetics — Posted on 2023-06-25

955 Evolution of Plasticity in Response to Ethanol between Recently Separated Populations of D. melanogaster with Different Ecological Histories

Sarfo-Boateng, G.; Scherping-Bustos, F.; Mammadov, M.; Signor, S.

10.1101/2023.06.22.546145 — evolutionary biology — Posted on 2023-06-25

956 Historic museum samples provide evidence for a recent replacement of Wolbachia types in European Drosophila melanogaster.

Strunov, A.; Kirchner, S.; Schindelar, J.; Kruckenhauser, L.; Haring, E.; Kapun, M.

10.1101/2023.06.25.546460 — evolutionary biology — Posted on 2023-06-25

957 Short-term thinning effect on inter- and intra-annual radial increment of Mediterranean Scots pine-oak mixed forest

Aldea, J.; del Rio, M.; Cattaneo, N.; Riofrio, J.; Ordonez, A. C.; Uzquiano, S.; Bravo, F.

10.1101/2023.06.22.546107 — ecology — Posted on 2023-06-25

958 A non-invasive photoactivatable split-Cre recombinase system for genome engineering in zebrafish.

ELSAID, R.; Mikdache, A.; Diabangouaya, P.; Gros, G.; Hernandez, P.

10.1101/2023.06.23.546268 — developmental biology — Posted on 2023-06-25

959 PINK1 Deficiency Alters Muscle Stem Cell Fate Decision And Muscle Regenerative Capacity.

Cairns, G.; Thumiah-Mootoo, M.; Abbasi, M. R.; Racine, J.; Lariovov, N.; Prola, A.; Khacho, M.; Burelle, Y.

10.1101/2023.06.23.546123 — cell biology — Posted on 2023-06-25

960 Prolonged Kaposi's Sarcoma-associated Herpesvirus vIL-6 Exposure Enhances Inflammatory Responses by Epigenetic Reprogramming

Inagaki, T.; Wang, K.-H.; Kumar, A.; Izumiya, C.; Miura, H.; Komaki, S.; Davis, R. R.; Tepper, C.; Katano, H.; Shimoda, M.; Izumiya, Y.

10.1101/2023.06.25.546454 — microbiology — Posted on 2023-06-25

961 Serum amyloid A-dependent inflammasome activation and acute injury in a mouse model of experimental stroke

Yu, J. S.; Zhu, H.; Taheri, S.; Lee, J.-Y.; Diamond, D. M.; Kirstein, C.; Kindy, M. S.

10.1101/2023.06.22.546125 — neuroscience — Posted on 2023-06-25

962 Time-varying Functional Connectivity Predicts Fluctuations in Sustained Attention in a Serial Tapping Task

Seeburger, D. T.; Xu, N.; Ma, M.; Larson, S.; Godwin, C.; Keilholz, S.; Schumacher, E. H.

10.1101/2023.06.22.546092 — neuroscience — Posted on 2023-06-25

963 Baseline Pupil Size Seems Unrelated to Fluid Intelligence, Working Memory Capacity, and Attentional Control

Ruuskanen, V.; Espeseth, T.; Hagen, T.; Mathot, S.

10.1101/2023.06.22.546078 — neuroscience — Posted on 2023-06-25

964 Closed-loop control of functional electrical stimulation using a selectively recording and bidirectional nerve cuff interface

Hwang, Y.-C. E.; Long, L.; Filho, J. S.; Genov, R.; Zariffa, J.

10.1101/2023.06.22.546126 — neuroscience — Posted on 2023-06-25

965 Early Deficits in Dentate Circuit and Behavioral Pattern Separation after Concussive Brain Injury

Corrubia, L.; Huang, A.; Nguyen, S.; Shiflett, M. W.; Jones, M.; Ewell, L.; Santhakumar, V.

10.1101/2023.06.22.546120 — neuroscience — Posted on 2023-06-25

966 Enabling Success Through Transformative Practices in STEM: The Effects of Applying an Anti-Deficit Framework to Diversity and Equity Programming

Duncan, D. S.; Jackson, J. L.; Collins, S.; Teherani, A.

10.1101/2023.06.22.546152 — scientific communication and education — Posted on 2023-06-25

967 wTSA-CRAFT : an open-access web server for rapid analysis of thermal shift assay experiments

Reys, V.; Kowalewski, J.; Gelin, M.; Lionne, C.

10.1101/2023.06.22.546086 — bioinformatics — Posted on 2023-06-25

968 Strong Elastic Protein Nanosheets Enable the Culture and Differentiation of Induced Pluripotent Stem Cells on Microdroplets

Mojares, E.; Chrysanthou, A.; Gautrot, J.

10.1101/2023.06.22.546128 — bioengineering — Posted on 2023-06-25

969 Doublecortin regulates neuronal migration by editing the tubulin code

Sebastien, M.; Prowse, E. N. P.; Hendricks, A. G.; Brouhard, G. J.

10.1101/2023.06.02.543327 — cell biology — Posted on 2023-06-25

970 Knockout of HD domain 5-nucleotidase in T. brucei triggers cell death linked to DNA damage and downregulation of glutamine uptake

Deng, Y. W.; Pontikos, M. A.; Baniasadi, H.; Williams, N. S.; Phillips, M. A.

10.1101/2023.06.19.545529 — microbiology — Posted on 2023-06-25

971 Modeling wild type and mutant p53 in telomerase-immortalized human cells

Miciak, J. J.; Bunz, F.

10.1101/2023.06.22.546141 — cancer biology — Posted on 2023-06-25

972 Intracellular Proteomics and Extracellular Vesiculomics as a Metric of Disease Recapitulation in 3D Bioprinted Aortic Valve Arrays

Clift, C. L.; Blaser, M. C.; Gerrits, W.; Turner, M. E.; Sonawane, A. C.; Pham, T.; Andresen, J. L.; Fenton, O. S.; Grolman, J. M.; Buffolo, F.; Schoen, F. J.; Hjortnaes, J.; Muehlschlegel, J. D.; Mooney, D. D.; Aikawa, M.; Singh, S. A.; Langer, R.; Aikawa, E.

10.1101/2023.06.22.546103 — bioengineering — Posted on 2023-06-25

973 Multi-Response Phylogenetic Mixed Models: Concepts andApplication

Halliwell, B.; Yates, L. A.; Holland, B. R.

10.1101/2022.12.13.520338 — evolutionary biology — Posted on 2023-06-25

974 The impact of ROI extraction method for MEG connectivity estimation: practical recommendations for the study of resting state data.

Brkic, D.; Sommariva, S.; Schuler, A.-L.; Pascarella, A.; Belardinelli, P.; Isabella, S. L.; Di Pino, G.; Zago, S.; Ferrazzi, G.; Rasero, J.; Arcara, G.; Marinazzo, D.; Pellegrino, G.

10.1101/2023.06.20.545792 — neuroscience — Posted on 2023-06-25

975 Parametric modeling of mechanical effects on circadian oscillators

Kennedy, K. E.; Abenza, J. F.; Rossetti, L.; Trepat, X.; Villoslada, P.; Garcia-Ojalvo, J.

10.1101/2023.06.24.546379 — systems biology — Posted on 2023-06-25

976 Overexpression of MUC1 influences the anti-proliferative effect of STAT3-inhibitor Napabucasin in epithelial cancers.

Bose, M.; Sanders, A.; Handa, A.; Vora, A.; Brouwer, C.; Mukherjee, P.

10.1101/2023.06.22.546177 — cancer biology — Posted on 2023-06-25

977 In search of the Goldilocks zone for hybrid speciation II: hard times for hybrid speciation?

Blanckaert, A.; Sriram, V.; Bank, C.

10.1101/2023.02.15.528680 — evolutionary biology — Posted on 2023-06-25

978 Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

Pang, L.-Y.; DeLuca, S.; Zhu, H.; Urban, J.; Spradling, A. C.

10.1101/2023.05.31.543160 — developmental biology — Posted on 2023-06-25

979 Adverse outcomes in SARS-CoV-2 infected pregnant mice are gestational age-dependent and resolve with antiviral treatment

Creisher, P. S.; Perry, J. L.; Zhong, W.; Lei, J.; Mulka, K. R.; Ryan, H.; Zhou, R.; Akin, E. H.; Liu, A.; Mitzner, W.; Burd, I.; Pekosz, A.; Klein, S. L.

10.1101/2023.03.23.533961 — microbiology — Posted on 2023-06-25

980 The impact of ROI extraction method for MEG connectivity estimation: practical recommendations for the study of resting state data.

Brkic, D.; Sommariva, S.; Schuler, A.-L.; Pascarella, A.; Belardinelli, P.; Isabella, S. L.; Di Pino, G.; Ferrazzi, G.; Rasero, J.; Arcara, G.; Marinazzo, D.; Pellegrino, G.

10.1101/2023.06.20.545792 — neuroscience — Posted on 2023-06-25

981 Learning Perturbation-specific Cell Representations for Prediction of Transcriptional Response across Cellular Contexts

Keinan, G.; Sayal, K.; Gonen, A.; Zhu, J.; Granovsky, L.; England, J.

10.1101/2023.03.20.533433 — systems biology — Posted on 2023-06-25

982 Effect of mitochondrial circulation on mitochondrial age density distribution

Kuznetsov, I. A.; Kuznetsov, A. V.

10.1101/2022.12.01.518783 — biophysics — Posted on 2023-06-25

983 The multilevel society of proboscis monkeys with a possible patrilineal basis

Matsuda, I.; Murai, T.; Grueter, C. C.; Tuuga, A.; Goossens, B.; Bernard, H.; Yahya, N. K.; Orozco-terWengel, P.; Salgado-Lynn, M.

10.1101/2023.01.24.525467 — animal behavior and cognition — Posted on 2023-06-25

984 Large genetic variability of maize leaf palatability to european corn borer : metabolic insights

Sanane, I.; Nicolas, S.; Bauland, C.; Marion-Poll, F.; Nous, C.; Legrand, J.; Dillmann, C.

10.1101/2023.04.12.536551 — genetics — Posted on 2023-06-25

985 Genetic population structure across Brittany and the downstream Loire basin provides new insights on the demographic history of Western Europe

Alves, I.; Giemza, J.; Blum, M.; Bernhardsson, C.; Chatel, S.; Karakachoff, M.; Saint Pierre, A.; Herzig, A. F.; Olaso, R.; Monteil, M.; Gallien, V.; Cabot, E.; Svensson, E.; Bacq Daian, D.; Baron, E.; Berthellier, C.; Besse, C.; Blanche, H.; Bocher, O.; Boland, A.; Bonnaud, S.; Charpentier, E.; Dandine-Roulland, C.; Ferec, C.; Fruchet, C.; Lecointe, S.; Le Floch, E.; Ludwig, T. E.; Marenne, G.; Meyer, V.; Quellery, E.; Racimo, F.; Rouault, K.; Sandron, F.; Schott, J.-J.; Velo Suarez, L.; Violleau, J.; Willerslev, E.; Coativy, Y.; Jezequel, M.; Le Bris, D.; Nicolas, C.; Pailler, Y.; Goldberg,

10.1101/2022.02.03.478491 — genetics — Posted on 2023-06-25

986 Rocket-miR, a Translational Launchpad for miRNA-based Antimicrobial Drug Development

Neff, S. L.; Hampton, T. H.; Koeppen, K.; Sarkar, S.; Latario, C. J.; Ross, B.; Stanton, B. A.

10.1101/2023.06.22.546111 — bioinformatics — Posted on 2023-06-25

987 Technique for rapidly forming networks of microvessel-like structures

Hewes, S.; Ahmad, F.; Connell, J.; Grande-Allen, K. J.

10.1101/2023.06.22.546165 — bioengineering — Posted on 2023-06-25

988 Maternal regulation of the vertebrate egg-to-embryo transition

Fuentes, R.; Marlow, F.; Abrams, E.; Zhang, H.; Kobayashi, M.; Gupta, T.; Kapp, L.; DiNardo, Z.; Heller, R.; Cisternas, R.; Montecinos-Franjola, F.; Vought, W.; Mullins, M. C.

10.1101/2023.06.22.546181 — developmental biology — Posted on 2023-06-25

989 Phenotypic Switching of Vascular Smooth Muscle Cells in Duchenne Muscular Dystrophy

Xuan, W.; Cheng, F.; Han, X.; Tipparaju, S.; Ashraf, M.

10.1101/2023.06.23.546309 — cell biology — Posted on 2023-06-25

990 Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses

Emmerich, K. B.; Walker, S. L.; Wang, G.; White, D. T.; Ceisel, A.; Wang, F.; Teng, Y.; Chunawala, Z.; Graziano, G.; Nimmagadda, S.; Saxena, M. T.; Qian, J.; Mumm, J. S.

10.1101/2020.08.04.236299 — neuroscience — Posted on 2023-06-25

991 GDF15 is a Critical Renostat in the Defense Against Hypoglycemia

Li, Z.; Zhang, X.; Zhu, W.; Xu, Q.; Yu, C.; Zhao, Q.; Siebel, S.; Zhang, C.; Costa Lima, B. G.; Li, X.; Israni-Winger, K.; Nasiri, A. R.; Caplan, M. J.; Chang, R. B.; Wang, A.; Belfort de Aguiar, R.; Hwang, J. J.; Perry, R. J.

10.1101/2023.06.22.546095 — physiology — Posted on 2023-06-25

992 α-tubulin regulation by 5' introns in S. cerevisiae

Wethekam, L. C.; Moore, J.

10.1101/2023.06.22.546163 — genetics — Posted on 2023-06-25

993 Structural insights into Rad18 targeting by the SLF1 BRCT domains

Huang, W.; Qiu, F.; Zheng, L.; Shi, M.; Shen, M.; Zhao, X.; Xiang, S.

10.1101/2023.06.23.546354 — biochemistry — Posted on 2023-06-25

994 Rapid Adaption of Cellular Metabolic Rate to the microRNA Complements of Mammals, and its Relevance to the Evolution of Endothermy

Fromm, B.; Sorger, T.

10.1101/2022.11.24.517858 — evolutionary biology — Posted on 2023-06-25

995 Wildlife vaccination strategies for eliminating bovine tuberculosis at the wildlife-livestock interface

Pandey, A.; Feuka, A. B.; Cosgrove, M.; Moriarty, M.; Duffiney, A.; VerCauteren, K. C.; Campa, H.; Pepin, K. M.

10.1101/2023.06.22.546040 — ecology — Posted on 2023-06-25

996 Identification and Characterization of CtUGT3 as the Key Player of Astragalin Biosynthesis in Safflower

Ren, C.; Xi, Z.; Xian, B.; Chen, C.; Huang, X.; Jiang, H.; Chen, J.; Peng, C.; Pei, J.

10.1101/2023.06.22.546132 — plant biology — Posted on 2023-06-25

997 Changes in Environmental Stress over COVID-19 Pandemic Likely Contributed to Failure to Replicate Adiposity Phenotype Associated with Krtcap3

Szalanczy, A. M.; Giorgio, G.; Goff, E.; Seshie, O.; Grzybowski, M.; Klotz, J.; Geurts, A. M.; Redei, E. E.; Solberg Woods, L. C.

10.1101/2023.03.15.532439 — molecular biology — Posted on 2023-06-25

998 Hyperosmolarity-induced suppression of group B1 Raf-like protein kinases modulates drought-growth trade-off in Arabidopsis

Kamiyama, Y.; Katagiri, S.; Yamashita, K.; Li, Y.; Takase, H.; Umezawa, T.

10.1101/2023.06.23.546348 — plant biology — Posted on 2023-06-25

999 The evolution of cooperation in the unidirectional division of labor on a tree network

Nirjhor, M. S. A.; Nakamaru, M.

10.1101/2023.06.23.546218 — evolutionary biology — Posted on 2023-06-25

1000 The Na+ leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons

Ngodup, T.; Irie, T.; Elkins, S.; Trussell, L. O.

10.1101/2023.06.23.546323 — neuroscience — Posted on 2023-06-25

1001 Repression of Aurora kinase B prevents growth and tissue invasion in medulloblastoma

Gries, A.; Santhana Kumar, K.; Kuttler, F.; Grotzer, M. A.; Baumgartner, M.

10.1101/2023.06.23.545872 — cancer biology — Posted on 2023-06-25

1002 Transcriptomic Enrichment of Ferroptosis-Related Gene ACSL4 in Advanced Hepatic Fibrosis/Cirrhosis: Bioinformatics Analysis and Experimental validation

Zhang, S.; Liu, Y.; Chen, L.; Liu, Y.; Guo, Y.; Cheng, J.; Huang, J.

10.1101/2023.06.22.543838 — bioinformatics — Posted on 2023-06-25

1003 Rat Deconvolution as Knowledge Miner for Immune Cell Trafficking from Toxicogenomics Databases

Morita, K.; Mizuno, T.; Azuma, I.; Kusuhara, H.

10.1101/2023.06.20.545836 — bioinformatics — Posted on 2023-06-25

1004 Multi-trait GWAS for diverse ancestries: Mapping the knowledge gap

Troubat, L.; Fettahoglu, D.; Aschard, H.; Julienne, H.

10.1101/2023.06.23.546248 — genetics — Posted on 2023-06-25

1005 Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

Ratnasiri, K.; Zheng, H.; Toh, J.; Yao, Z.; Duran, V.; Donato, M.; Roederer, M.; Kamath, M.; Todd, J.-P. M.; Gagne, M.; Foulds, K. E.; Francica, J. R.; Corbett, K. S.; Douek, D. C.; Seder, R. A.; Einav, S.; Blish, C. A.; Khatri, P.

10.1101/2023.06.22.546003 — immunology — Posted on 2023-06-25

1006 Parasite-Induced IFN-g Regulates Host Defense via CD115 and mTOR-Dependent Mechanism of Tissue-Resident Macrophage Death

Martin, A.; Giri, S.; Safronova, A.; Eliseeva, S.; Kwok, S.; Yarovinsky, F.

10.1101/2023.06.23.546211 — immunology — Posted on 2023-06-25

1007 Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Hagihara, H.; Shoji, H.; Hattori, S.; Sala, G.; Takamiya, Y.; Tanaka, M.; Ihara, M.; Shibutani, M.; Hatada, I.; Hori, K.; Hoshino, M.; Nakao, A.; Mori, Y.; Okabe, S.; Matsushita, M.; Urbach, A.; Katayama, Y.; Matsumoto, A.; Nakayama, K. I.; Katori, S.; Sato, T.; Iwasato, T.; Nakamura, H.; Goshima, Y.; Raveau, M.; Tatsukawa, T.; Yamakawa, K.; Kasai, H.; Takahashi, N.; Inazawa, J.; Nobuhisa, I.; Kagawa, T.; Taga, T.; Darwish, M.; Nishizono, H.; Takao, K.; Sapkota, K.; Nakazawa, K.; Takagi, T.; Fujisawa, H.; Sugimura, Y.; Yamanishi, K.; Rajagopal, L.; Hannah, N. D.; Meltzer, H. Y.; Yamamoto, T.;

10.1101/2021.02.02.428362 — neuroscience — Posted on 2023-06-25

1008 Opto-seq reveals input-specific immediate early gene induction in ventral tegmental area cell types

Simon, R. C.; Loveless, M. C.; Yee, J. X.; Hashikawa, K.; Stuber, G. D.; Zweifel, L. S.; Soden, M. E.

10.1101/2023.06.22.546124 — neuroscience — Posted on 2023-06-25

1009 Single neuron analysis of aging associated changes in learning reveals progressive impairmentsin transcriptional plasticity

Badal, K. K.; Sadhu, A.; McCracken, C.; Raveendra, B. L.; Lozano-Villada, S.; Shetty, A. C.; Gillette, P.; Zhao, Y.; Stommes, D.; Fieber, L. A.; Schmale, M. C.; Mahurkar, A.; Hawkins, R. D.; Puthanveettil, S. V.

10.1101/2023.06.23.546336 — neuroscience — Posted on 2023-06-25

1010 A weighted generative model of the human connectome

Akarca, D.; Schiavi, S.; Achterberg, J.; Genc, S.; Jones, D.; Astle, D.

10.1101/2023.06.23.546237 — neuroscience — Posted on 2023-06-25

1011 Peak-agnostic high-resolution cis-regulatory circuitry mapping using single cell multiome data

Zhang, Z.; Ruf-Zamojski, F. M.; Zamojski, M.; Bernard, D. J.; Chen, X.; Troyanskaya, O. G.; Sealfon, S.

10.1101/2023.06.23.544355 — bioinformatics — Posted on 2023-06-24

1012 ShinyMultiome.UiO: An interactive open-source framework utilizing Seurat Objects for visualizing single-cell Multiomes

Akshay, A.; Sharma, A.; Eskeland, R.

10.1101/2023.06.20.545756 — bioinformatics — Posted on 2023-06-25

1013 Biosys-LiDeOGraM: A visual analytics framework for interactive modelling of multiscale biosystems

Mejean Perrot, N.; Layec, S.; Tonda, A.; Boukhelifa, N.; Fonseca, F.; Lutton, E.

10.1101/2023.06.23.546209 — bioengineering — Posted on 2023-06-24

1014 Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model

Dark, C.; Ali, N.; Golenkina, S.; Blazev, R.; Parker, B. L.; Murphy, K.; Lynch, G. S.; Senapati, T.; Millard, S.; Judge, S. M.; Judge, A. R.; Cheng, L.

10.1101/2023.06.23.546217 — developmental biology — Posted on 2023-06-24

1015 Monitoring norepinephrine release in vivo using next-generation GRABNE sensors

Feng, J.; Dong, H.; Lischinsky, J. E.; Zhou, J.; Deng, F.; Zhuang, C.; Miao, X.; Wang, H.; Xie, H.; Cui, G.; Lin, D.; Li, Y.

10.1101/2023.06.22.546075 — neuroscience — Posted on 2023-06-25

1016 Rice OsHAK18 mediates shoot-to-root circulation of potassium and sodium and source-to-sink transport of soluble sugar

Peng, L.; Xiao, H.; Li, R.; Zeng, Y.; Gu, M.; Moran, N.; Yu, L.; Xu, G.

10.1101/2023.03.27.534432 — plant biology — Posted on 2023-06-24

1017 Fine-tuning Protein Embeddings for GeneralizableAnnotation Propagation

Dickson, A. M.; Mofrad, M. R. K.

10.1101/2023.06.22.546084 — bioinformatics — Posted on 2023-06-24

1018 MOCHA: Advanced statistical modeling of scATAC-seq data enables functional genomic inference in large human disease cohorts

Rachid Zaim, S.; Pebworth, M.-P.; McGrath, I.; Okada, L.; Weiss, M.; Reading, J.; Czartoski, J. L.; Torgerson, T.; McElrath, M. J.; Bumol, T. F.; Skene, P. J.; Li, X.-j.

10.1101/2023.06.23.544827 — bioinformatics — Posted on 2023-06-24

1019 Bioinformatic Surveillance Leads to Discovery of Two Novel Putative Bunyaviruses Associated with Black Soldier Fly

Walt, H. K.; Kooienga, E.; Cammack, J. A.; Tomberlin, J. K.; Jordan, H. R.; Meyer, F.; Hoffmann, F. G.

10.1101/2023.06.23.545759 — bioinformatics — Posted on 2023-06-24

1020 Vocabulary Matters: An Annotation Pipeline and Two Deep Learning Algorithms for Enzyme Named Entity Recognition

Wang, M.; Vijayaraghavan, A.; Beck, T.; Posma, J. M.

10.1101/2023.06.23.546229 — bioinformatics — Posted on 2023-06-24

1021 Investigation of the usefulness of liver-specific deconvolution method toward legacy data utilization

Azuma, I.; Mizuno, T.; Morita, K.; Kusuhara, H.

10.1101/2023.04.19.537436 — bioinformatics — Posted on 2023-06-24

1022 Proteolytic Remodeling of 3D Bioprinted Tumor Microenvironments

Rasti Boroojeni, F.; Naeimipour, S.; Lifwergren, P.; Abrahamsson, A.; Dabrosin, C.; Selegard, R.; Aili, D.

10.1101/2023.06.22.546066 — bioengineering — Posted on 2023-06-24

1023 The Tabulae Paralytica: Multimodal single-cell and spatial atlases of spinal cord injury

Skinnider, M. A.; Gautier, M.; Teo, A. Y. Y.; Kathe, C.; Hutson, T.; Laskaratos, A.; de Coucy, A.; Regazzi, N.; Aureli, V.; James, N. D.; Schneider, B.; Sofroniew, M.; Barraud, Q.; Bloch, J.; Anderson, M. A.; Squair, J.; Courtine, G.

10.1101/2023.06.23.544348 — genomics — Posted on 2023-06-24

1024 Functional stress responses in Glaucophyta: evidence of ethylene and ABA functions in C. paradoxa

Genot, B.; Grogan, M.; Yost, M.; Iacono, G.; Archer, S. D.; Burns, J. A.

10.1101/2023.06.22.546102 — evolutionary biology — Posted on 2023-06-24

1025 Alternative splicing and environmental adaptation in house mice

Manahan, D. N.; Nachman, M. W.

10.1101/2023.06.23.546335 — evolutionary biology — Posted on 2023-06-24

1026 The impact of Quaternary Amazonian river dynamics on patterns and process of diversification in uakari monkeys (genus Cacajao)

Silva, F. E.; Luna, L. W.; Batista, R.; Rhöe, F.; Gubili, C.; Farias, I. P.; Hrbek, T.; do Amaral, J. V.; Ribas, C. C.; McDevitt, A. D.; Dellicour, S.; Flot, J.-F.; Boubli, J. P.

10.1101/2023.06.23.546215 — evolutionary biology — Posted on 2023-06-24

1027 Pollen viability of a widespread plant in response to climate warming: possible local adaptation of populations from different elevations

Hruba, K.; Biella, P.; Klecka, J.

10.1101/2023.06.22.546116 — ecology — Posted on 2023-06-24

1028 Interactive effects of salinity, temperature and food web configuration on performance and harmfulness of the raphidophyte Heterosigma akashiwo

Giesler, J. K.; Lemley, D. A.; Adams, J. B.; Moorthi, S. D.

10.1101/2023.06.23.546213 — ecology — Posted on 2023-06-24

1029 Essential Function of Membrane-Bound Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development

Xu, Z.; Wang, Z.; Wang, L.; Qi, Y.

10.1101/2023.06.22.546200 — developmental biology — Posted on 2023-06-24

1030 WRNIP1 prevents transcription-associated genomic instability

Valenzisi, P.; Marabitti, V.; Pichierri, P.; Franchitto, A.

10.1101/2023.06.23.546223 — cell biology — Posted on 2023-06-24

1031 Cell swelling enhances GPCR ternary complex formation, underpinning the potentiation of beta2 adrenergic receptor-mediated cAMP response

Sirbu, A.; Bathe-Peters, M.; Inoue, A.; Lohse, M.; Annibale, P.

10.1101/2023.06.23.544496 — cell biology — Posted on 2023-06-24

1032 Periosteal response to bone fracture at single nuclei resolution

Perrin, S.; Wotawa, C.-A.; Luka, M.; Coulpier, F.; Masson, C.; Menager, M.; Colnot, C.

10.1101/2023.06.23.546220 — cell biology — Posted on 2023-06-24

1033 Updating the sulcal landscape of the human lateral parieto-occipital junction provides anatomical, functional, and cognitive insights

Willbrand, E. H.; Tsai, Y.-H.; Gagnant, T.; Weiner, K. S.

10.1101/2023.06.08.544284 — neuroscience — Posted on 2023-06-24

1034 Timecourse and source localization of abstract and concrete semantic representations.

Vignali, L.; Xu, Y.; Turini, J.; Collignon, O.; Crepaldi, D.; Bottini, R.

10.1101/2023.06.23.546231 — neuroscience — Posted on 2023-06-24

1035 SWI/SNF chromatin remodeling determines brassinosteroid-induced transcriptional activation

Zhu, T.; Wei, C.; yu, y.; Zhu, J.; Liang, Z.; Cui, Y.; Wang, Z.-Y.; Li, C.

10.1101/2023.06.23.544932 — plant biology — Posted on 2023-06-24

1036 PARP14 is a writer, reader and eraser of mono-ADP-ribosylation

Torretta, A.; Chatzicharalampous, C.; Ebenwaldner, C.; Schuler, H.

10.1101/2023.06.24.546374 — biochemistry — Posted on 2023-06-24

1037 Weak interactions cause poor performance of common network inference models

Sadykova, D.; Yearsley, J. M.; Aderhold, A.; Dondelinger, F.; White, H. J.; Sanchez, L. L.; Ilic, M.; Sadykov, A.; Emmerson, M.; Caplat, P.

10.1101/2023.06.22.546059 — ecology — Posted on 2023-06-24

1038 Chronic Stress Increases Adiposity and Anxiety in Rats with Decreased Expression of Krtcap3

Szalanczy, A. M.; Fitzpatrick, M. K.; Beeson, A.; Bui, T.; Dyson, C.; Eller, S.; Landry, J.; Scott, C.; Grzybowski, M.; Klotz, J.; Geurts, A. M.; Weiner, J. L.; Redei, E. E.; Solberg Woods, L. C.

10.1101/2023.06.24.546378 — molecular biology — Posted on 2023-06-24

1039 Diverse viral cas genes antagonize CRISPR immunity

Katz, M. A.; Sawyer, E. M.; Kozlova, A.; Williams, M. C.; Margolis, S. R.; Oriolt, L.; Johnson, M.; Bondy-Denomy, J.; Meeske, A. J.

10.1101/2023.06.24.545427 — microbiology — Posted on 2023-06-24

1040 Particle deformability enables control of interactions between membrane-anchored nanoparticles

Nambiar, N.; Loyd, Z. A.; Abel, S. M.

10.1101/2023.06.22.546201 — biophysics — Posted on 2023-06-24

1041 The universal suppressor mutation in the HSV-1 nuclear egress complex restores membrane budding defects by stabilizing the oligomeric lattice

Draganova, E. B.; Wang, H.; Wu, M.; Liao, S.; Vu, A.; Gonzalez-Del Pino, G.; Zhou, Z. H.; Roller, R. J.; Heldwein, K.

10.1101/2023.06.22.546118 — biophysics — Posted on 2023-06-24

1042 A mean-field to capture asynchronous irregular dynamics of conductance-based networks of adaptive quadratic integrate-and-fire neuron models

Alexandersen, C. G.; Duprat, C.; Ezzati, A.; Houzelstein, P.; Ledoux, A.; Liu, Y.; Saghir, S.; Destexhe, A.; Tesler, F.; Depannemaecker, D.

10.1101/2023.06.22.546071 — bioinformatics — Posted on 2023-06-24

1043 Accurate prediction of protein assembly structure by combining AlphaFold and symmetrical docking

Jeppesen, M.; Andre, I.

10.1101/2023.06.22.546069 — bioinformatics — Posted on 2023-06-24

1044 DeepRank-GNN-esm: A Graph Neural Network for Scoring Protein-Protein Models using Protein Language Model

Xu, X.; Bonvin, A. M.

10.1101/2023.06.22.546080 — bioinformatics — Posted on 2023-06-24

1045 Robust Homeostasis of Cellular Cholesterol via Antithetic Integral Control

Scheepers, R.; Araujo, R.

10.1101/2023.06.24.546224 — biochemistry — Posted on 2023-06-24

1046 A fast method to distinguish between fermentative and respiratory metabolisms in single yeast cells

Luzia, L.; Battjes, J.; Zwering, E.; Jansen, D.; Melkonian, C.; Teusink, B.

10.1101/2023.06.23.546324 — systems biology — Posted on 2023-06-24

1047 Harnessing Escherichia coli Dark Genome to Produce Anti-Alzheimer Peptides

Verma, N.; Manvati, S.; Dhar, P.

10.1101/2023.06.23.546343 — synthetic biology — Posted on 2023-06-24

1048 Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery

Liang, X.; Gupta, D.; Xie, J.; Wonterghem, E. V.; Hoecke, L. V.; Hean, J.; Niu, Z.; Wiklander, O. P. B.; Zheng, W.; Wiklander, R. J.; He, R.; Mamand, D. R.; Bost, J.; Zhou, G.; Zhou, H.; Roudi, S.; Zickler, A. M.; Gorgens, A.; Hagey, D.; de Jong, O. G.; Uy, A. G.; Zong, Y.; Mager, I.; Perez, C. M.; Roberts, T. C.; Vader, P.; Fougerolles, A. d.; Wood, M. J. A.; Vandenbroucke, R. E.; Nordin, J. Z.; EL Andaloussi, S.

10.1101/2023.04.30.535834 — bioengineering — Posted on 2023-06-24

1049 Phosphorylation of Gαi shapes canonical Gα(i)βγ/GPCR signaling

Roy, S.; Sinha, S.; Silas, A. J.; Ghassemian, M.; Kufareva, I.; Ghosh, P.

10.1101/2022.09.11.507491 — cell biology — Posted on 2023-06-24

1050 hnRNPM and ELAVL1 control type I interferon induction by promoting IRF3 phosphorylation downstream of both cGAS and RIG-I

Kirchhoff, A.; Herzner, A.-M.; Urban, C.; Piras, A.; Düster, R.; Wegner, J.; Grünewald, A.; Schlee-Guimaraes, T. M.; Ciupka, K.; Leka, P.; Bootz, R. J.; de Regt, A. K.; Kümmerer, B.; Honholt Christensen, M.; Schmidt, F. I.; Günther, C.; Kato, H.; Bartok, E.; Hartmann, G.; Geyer, M.; Pichlmair, A.; Schlee, M.

10.1101/2023.06.23.545108 — immunology — Posted on 2023-06-24

1051 B cell and antibody targeting of transplant alloantigen epitopes is supported by both self and allo-recognition

Killian, J. T.; King, R. G.; Kizziah, J. L.; Fucile, C. F.; Diaz-Avalos, R.; Qiu, S.; Silva-Sanchez, A.; Mousseau, B. J.; Macon, K. J.; Callahan, A. R.; Yang, G.; Hossain, M. E.; Akther, J.; Houp, J. A.; Rosenblum, F. D.; Porrett, P. M.; Ong, S. C.; Kumar, V.; Saphire, E. O.; Kearney, J. F.; Randall, T. D.; Rosenberg, A. F.; Green, T. J.; Lund, F. E.

10.1101/2023.03.31.534734 — immunology — Posted on 2023-06-24

1052 A transient protein folding response targets aggregation in the early phase of TDP-43-mediated disease

San Gil, R.; Pascovici, D.; Venturato, J.; Brown-Wright, H.; Mehta, P.; Madrid San Martin, L.; Wu, J.; Chui, Y. K.; Bademosi, A.; Swaminathan, S.; Luan, W.; Berning, B. A.; Wright, A. L.; Keating, S. S.; Lee, A.; Morsch, M.; Chung, R. S.; Lisowski, L.; Mirzaei, M.; Walker, A. K.

10.1101/2023.06.21.546009 — neuroscience — Posted on 2023-06-24

1053 Distinct brain network features predict internalizing and externalizing traits in children and adults

Qu, Y. L.; Chen, J.; Tam, A.; Ooi, L. Q. R.; Dhamala, E.; Cocuzza, C.; Lawhead, C.; Yeo, B. T. T.; Holmes, A.

10.1101/2023.05.20.541490 — neuroscience — Posted on 2023-06-24

1054 DNA binding activity of CAMTA3 is essential for its function

Reddy, A. S. N.; Prasad, K. V. S. K.; Abdel-Hameed, A.; Jiang, Q.

10.1101/2023.06.22.546133 — plant biology — Posted on 2023-06-24

1055 Multiscale Computational Framework to Investigate Integrin Mechanosensing and Cell Adhesion

Montes, A. R.; Gutierrez, G.; Buganza Tepole, A.; Mofrad, M.

10.1101/2023.03.24.533575 — biophysics — Posted on 2023-06-24

1056 Se-Glargine I. Chemical Synthesis of a Basal Insulin Analog Stabilized by an Internal Diselenide Bridge

Weil-Ktorza, O.; Dhayalan, B.; Weiss, M. A.; Metanis, N.

10.1101/2023.06.23.546304 — biochemistry — Posted on 2023-06-24

1057 Se-Glargine II. Native Function of a Basal Insulin Analog Stabilized by an Internal Diselenide Bridge

Chen, Y.-S.; Dhayalan, B.; Yang, Y.; Weil-Ktorza, O.; Metanis, N.; Weiss, M. A.

10.1101/2023.06.24.546337 — biochemistry — Posted on 2023-06-24

1058 Stereoscopic RNA Analysis of Transcriptional and Post-transcriptional Regulation

Lee, S. A.; Kwak, H.

10.1101/2023.06.22.546182 — genomics — Posted on 2023-06-24

1059 Alpha-tubulin regulation by 5 introns in S. cerevisiae

Wethekam, L. C.; Moore, J.

10.1101/2023.06.22.546163 — genetics — Posted on 2023-06-24

1060 CRISPR/Cas9 gene editing to generate Drosophila LexA lines in secondary school classes

Rankin, A. E.; Fox, E.; Chisholm, T.; Lantz, N.; Rajan, A.; Phillips, W.; Griffin, E.; Harper, J.; Suhr, C.; Tan, M.; Wang, J.; Yang, A.; Kim, E. S.; Ankrah, N. K. A.; Chakraborty, P.; Lam, A. C. K.; Laws, M. E.; Lee, J.; Park, K.; Wesel, E.; Covert, P. H.; Kockel, L.; Park, S.; Kim, S. K.

10.1101/2023.06.22.546134 — genetics — Posted on 2023-06-24

1061 BRG1 establishes the neuroectodermal chromatin landscape to restrict dorsal cell fates

Hoffman, J. A.; Muse, G. W.; Langer, L. F.; Gandara, I.; Ward, J. M.; Archer, T. K.

10.1101/2023.06.24.546365 — molecular biology — Posted on 2023-06-24

1062 Theft of Host Transferrin Receptor-1 by Toxoplasma gondii is required for infection

Denton, S. L.; Mejia, A.; Nevarez, L. L.; Soares, M. P.; Fox, B. A.; Bzik, D. J.; Gigley, J. P.

10.1101/2023.06.23.546322 — microbiology — Posted on 2023-06-24

1063 Intrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly

Ni, T.; Jiang, Q.; Ng, P. C.; Shen, J.; Dou, H.; Zhu, Y.; Radecke, J.; Dykes, G. F.; Huang, F.; Liu, L.-N.; Zhang, P.

10.1101/2023.06.24.546370 — microbiology — Posted on 2023-06-24

1064 The effects of nano'' and microplastic ingestion on the survivorship and reproduction of Aedes aegypti (L.) and Aedes albopictus (Skuse)

McConnel, G.; Lawson, J.; Canas-Carrell, J. E.; Brelsfoard, C. L.

10.1101/2023.06.23.546347 — microbiology — Posted on 2023-06-24

1065 Increased error rate and delayed response to negative emotional stimuli in antisaccade task in obsessive-compulsive disorder

Khayrullina, G.; Panfilova, E.; Martynova, O.

10.1101/2023.06.21.545955 — neuroscience — Posted on 2023-06-24

1066 Phase-locking of hippocampal CA3 neurons to distal CA1 theta oscillations selectively predicts memory performance

Sauvage, M. M.; Ku, S.-P.; Atucha, E.; Alavi, N.; Yoshida, M.; Csicsvari, J.

10.1101/2023.06.21.546025 — neuroscience — Posted on 2023-06-24

1067 Reduced Reverse Replay in Anxious Individuals Impairs Reward Prediction

Yu, Q.; Luo, Y.; Dolan, R. J.; Ou, J.; Huang, C.; Wang, H.; Xiao, Z.; Liu, Y.

10.1101/2023.06.21.546031 — neuroscience — Posted on 2023-06-24

1068 A synthetic biology approach to assemble and reboot clinically-relevant Pseudomonas aeruginosa tailed phages

Ipoutcha, T.; Racharaks, R.; Huttelmaier, S.; Wilson, C. J.; Ozer, E. A.; Hartmann, E. M.

10.1101/2023.06.23.546310 — synthetic biology — Posted on 2023-06-24

1069 Deep neural networks for predicting single cell responses and probability landscapes

Klumpe, H.; Lugagne, J.-B.; Khalil, A. S.; Dunlop, M.

10.1101/2023.06.24.546373 — synthetic biology — Posted on 2023-06-24

1070 The probiotic roles of Lactiplantibacillus plantarum E2 as a dietary supplement in growth promotion and disease resistance of juvenile large yellow croaker (Larimichthys crocea)

Ruizhe, L.; Shan, W.; Dongliang, H.; Yulu, H.; Tianliang, H.; Xinhua, C.

10.1101/2023.06.24.544721 — zoology — Posted on 2023-06-24

1071 Retrospective Evaluation of the Eye Irritation Potential of Agrochemical Formulations

Choksi, N.; Latorre, A.; Catalano, S.; Grivel, A.; Baldassari, J.; Pires, J.; Corvaro, M.; Silva, M.; Ogasawara, M.; Inforzato, M.; Habe, P.; Murata, R.; Stinchcombe, S.; Kolle, S.; Masinja, W.; Perjessy, G.; Daniel, A.; Allen, D.

10.1101/2023.06.23.543016 — pharmacology and toxicology — Posted on 2023-06-24

1072 The retinal RNA editome is concentrated in photoreceptor-specific genes and genetically linked to vision loss

Ansell, B. R. E.; Bonelli, R.; Thomas, S. N.; Manda, A.; Ratnapriya, R.; Pinelli, M.; Swaroop, A.; diBernardo, D.; Banfi, S.; Bahlo, M.

10.1101/2023.06.22.543349 — genomics — Posted on 2023-06-24

1073 Life on the edge: a new toolbox for population-level climate change vulnerability assessments

Barratt, C. D.; Onstein, R. E.; Pinsky, M. L.; Steinfartz, S.; Kuehl, H. S.; Forester, B. R.; Razgour, O.

10.1101/2023.06.23.543988 — evolutionary biology — Posted on 2023-06-24

1074 Impact of random 50-base sequences inserted into an intron on splicing in Saccharomyces cerevisiae

Perchlik, M.; Sasse, A.; Mostafavi, S.; Fields, S.; Cuperus, J.

10.1101/2023.06.21.545966 — synthetic biology — Posted on 2023-06-24

1075 Body mass and growth rates predict protein intake across animals

Talal, S.; Harrison, J. F.; Farington, R.; Youngblood, J. P.; Medina, H. E.; Overson, R.; Cease, A.

10.1101/2023.06.20.545784 — ecology — Posted on 2023-06-24

1076 Coordinated wound responses in a regenerative animal-algal photosymbiotic metaorganism

Nanes Sarfati, D.; Xue, Y.; Song, E. S.; Byrne, A.; Le, D.; Darmanis, S.; Quake, S. R.; Burlacot, A.; Sikes, J.; Wang, B.

10.1101/2023.06.21.545945 — developmental biology — Posted on 2023-06-24

1077 The unique microbial diversity, community composition and networks of Pacific Islander endocervical and vaginal microbiomes in the presence or absence of Chlamydia trachomatis infection using metagenomic shotgun sequencing

Bommana, S.; Hu, Y.; Kama, M.; Wang, R.; Kodimerla, R.; Jijakli, K.; Read, T.; Dean, D.

10.1101/2023.06.23.546186 — microbiology — Posted on 2023-06-24

1078 Molecular physiological characterization of the dynamics of persister formation in Staphylococcus aureus.

Liu, S.; Huang, Y.; Jensen, S.; Laman, P.; Kramer, G.; Zaat, S. A. J.; Brul, S.

10.1101/2023.06.21.545909 — microbiology — Posted on 2023-06-24

1079 Comparative genomics between Colombian clinical isolates of Monophasic Variant Salmonella Typhimurium and international clonal lineages

Cuenca-Arias, P.; Montano Valencia, L. A.; Rodriguez, E. C.; Ruiz-Moreno, H. A.; Montilla-Escudero, E. A.; Villarreal, J. M.; Wiesner-Reyes, M.

10.1101/2023.06.23.546254 — microbiology — Posted on 2023-06-24

1080 The HPV8 E6 protein targets the Hippo and Wnt signaling pathways as part of its arsenal to restrain keratinocyte differentiation

Munger, K.; Wu, S. C.; Grace, M.

10.1101/2023.06.22.546184 — microbiology — Posted on 2023-06-24

1081 Updating the sulcal landscape of the human lateral parieto-occipital junction provides anatomical, functional, and cognitive insights

Willbrand, E. H.; Tsai, Y.-H.; Gagnant, T.; Weiner, K. S.

10.1101/2023.06.08.544284 — neuroscience — Posted on 2023-06-24

1082 EARLY MATURITY 7 modifies the circadian clock and photoperiod sensitivity in barley

Helmsorig, G.; Walla, A.; Rütjes, T.; Buchmann, G.; Schüller, R.; Hensel, G.; von Korff, M.

10.1101/2023.06.22.546112 — plant biology — Posted on 2023-06-24

1083 Single-cell Transcriptomic Analysis of Salivary Gland Endothelial Cells

Altrieth, A. L.; Suarez, E.; Nelson, D. A.; Gabunia, S.; Larsen, M.

10.1101/2023.06.22.545817 — cell biology — Posted on 2023-06-24

1084 African swine fever virus I196L is a virulence determinant and its deletant induces robust protection in Domestic pig

Hu, R.; Fan, J.; Zhu, R.; Li, N.; Yang, J.; Yue, H.; Zhang, Y.; Zhou, X.; Ke, J.; Wang, Y.; Li, Q.; Qi, Y.; Miao, F.; Chen, T.; Li, M.

10.1101/2023.06.22.546121 — immunology — Posted on 2023-06-24

1085 Collagen type VI regulates TGFβ bioavailability in skeletal muscle

Mohassel, P.; Rooney, J.; Zou, Y.; Johnson, K.; Norato, G.; Hearn, H.; Nalls, M. A.; Yun, P.; Ogata, T.; Silverstein, S.; Sleboda, D.; Roberts, T. J.; Rifkin, D. B.; Bonnemann, C. G.

10.1101/2023.06.22.545964 — neuroscience — Posted on 2023-06-24

1086 The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling

Deng, X.; Peng, F.; Tang, X.; Lee, Y.-R. J.; Lin, H.; Liu, B.

10.1101/2023.06.22.545541 — plant biology — Posted on 2023-06-24

1087 Single-session measures of quadriceps neuromuscular function are reliable in healthy females and unaffected by age

O'Bryan, S. J.; Hiam, D.; Lamon, S.

10.1101/2023.06.22.545905 — physiology — Posted on 2023-06-24

1088 A robust association test leveraging unknown genetic interactions: Application to cystic brosis lung disease

Kim, S.; Strug, L. J.

10.1101/2023.06.22.546041 — genomics — Posted on 2023-06-24

1089 Nanobiopsy investigation of the subcellular mtDNA heteroplasmy in human tissues

Bury, A.; Vincent, A. E.; Pyle, A.; Actis, P.; Hudson, G.

10.1101/2023.06.22.546054 — genomics — Posted on 2023-06-24

1090 First large-scale peach gene coexpression network: A new tool for predicting gene function

Perez de los Cobos, F.; Garcia-Gomez, B. E.; Orduna-Rubio, L.; Batlle, I.; Arus, P.; Matus, J. T.; Eduardo, I.

10.1101/2023.06.22.546058 — genetics — Posted on 2023-06-24

1091 MEBRAINS 1.0: a new population-based macaque atlas

Balanq, P. F.; Zhu, Q.; Li, X.; Niu, M.; Rapan, L.; Funck, T.; Bakker, R.; Palomero-Gallagher, N.; Vanduffel, W.

10.1101/2023.06.21.545953 — neuroscience — Posted on 2023-06-24

1092 Micro-circulating hyperdynamic blood flow as a key pathogenic factor in early sepsis

Feng, X.; Zeng, Y.; Sun, Y. B.; Yu, B.-W.

10.1101/2023.06.04.543593 — pathology — Posted on 2023-06-24

1093 A systematic approach identifies p53-DREAM target genes associated with blood or brain abnormalities

Rakotopare, J.; Lejour, V.; Duval, C.; Eldawra, E.; Escoffier, H.; Toledo, F.

10.1101/2023.06.21.545932 — genetics — Posted on 2023-06-24

1094 Individual prediction tendencies do not generalise across modalities

Schubert, J.; Suess, N.; Weisz, N.

10.1101/2023.02.02.526758 — neuroscience — Posted on 2023-06-24

1095 Improving inversion of model parameters from action potential recordings with kernel methods

Oslandsbotn, A.; Forsch, N.; Cloninger, A.

10.1101/2023.03.15.532862 — systems biology — Posted on 2023-06-24

1096 The landscape of microRNA interactions annotation: analysis of three rare disorders as case study

Panni, S.; Panneerselvam, K.; Porras, P.; Duesbury, M.; Perfetto, L.; Licata, L.; Hermjakob, H.; Orchard, S.

10.1101/2023.06.20.545695 — bioinformatics — Posted on 2023-06-24

1097 Rat Deconvolution as Knowledge Miner for Immune Cell Trafficking from Toxicogenomics Databases

Morita, K.; Mizuno, T.; Azuma, I.; Kusuhara, H.

10.1101/2023.06.20.545836 — bioinformatics — Posted on 2023-06-24

1098 Re-investigating the correctness of decoy-based false discovery rate control in proteomics tandem mass spectrometry

Freestone, J. A.; Noble, W. S.; Keich, U.

10.1101/2023.06.21.546013 — bioinformatics — Posted on 2023-06-24

1099 Genetic disruption of dopamine β-hydroxylase dysregulates innate responses to predator odor in mice

Liu, J.; Lustberg, D. J.; McCann, K. E.; Weinshenker, D.

10.1101/2023.06.21.545975 — neuroscience — Posted on 2023-06-24

1100 RaptorX-Single: single-sequence protein structure prediction by integrating protein language models

Jing, X.; Wu, F.; Luo, X.; Xu, J.

10.1101/2023.04.24.538081 — bioinformatics — Posted on 2023-06-24

1101 ShinyMultiome.UiO: An interactive open-source framework utilizing Seurat Objects for visualizing single-cell Multiomes

Akshay, A.; Sharma, A.; Eskeland, R.

10.1101/2023.06.20.545756 — bioinformatics — Posted on 2023-06-24

1102 The Limits of Haplotype-Based Approaches: Exploring the Applicability of the Li and Stephens Haplotype-Copying Model to Ancient Samples

Diaz-Pines Cort, I.; Rubin, J. D.; Wad Sackett, P.; Renaud, G.

10.1101/2023.06.21.545876 — genomics — Posted on 2023-06-24

1103 Transcriptional profiling of aging tissues from female and male African turquoise killifish

Xu, A.; Teefy, B. B.; Lu, R. J.; Nozownik, S.; Tyers, A. M.; Valenzano, D. R.; Benayoun, B. A.

10.1101/2023.06.20.545766 — genomics — Posted on 2023-06-24

1104 Past family selection in Populus nigra leads to an amplification of rust damages when neighbors are related

Tiret, M.; Lascoux, M.; Sanchez, L.

10.1101/2023.06.21.545987 — genetics — Posted on 2023-06-24

1105 Do native and introduced cover crops differ in their ability to suppress weeds and reduce seedbanks? A Case study in a Table Grape Vineyard.

Fernando, M.; Hale, L.; Shrestha, A.

10.1101/2023.06.20.545823 — ecology — Posted on 2023-06-24

1106 A global baseline for qPCR-determined antimicrobial resistance gene prevalence across environments

Abramova, A.; Berendonk, T. U.; Bengtsson-Palme, J.

10.1101/2022.01.29.478248 — microbiology — Posted on 2023-06-24

1107 Prenatal Methadone Exposure Leads To Disruptions In Adult-Born Dentate Granule Cell Survival And Female Persistent Fear Responding

Gamble, M. E.; Diaz, M. R.

10.1101/2023.06.20.545764 — neuroscience — Posted on 2023-06-24

1108 Aberrant type 2 dopamine receptor availability in criminal psychopathy

Lukkarinen, L.; Tuisku, J.; Sun, L.; Helin, S.; Karlsson, H.; Venetjoki, N.; Salomaa, M.; Rautio, P.; Hirvonen, J.; Lauerma, H.; Tiihonen, J.; Nummenmaa, L.

10.1101/2023.06.21.545877 — neuroscience — Posted on 2023-06-24

1109 Maintaining task performance levels under cognitive load while walking requires widespread reallocation of neural resources: A Mobile Brain-Body Imaging (MoBI) study.

Patelaki, E.; Foxe, J. J.; McFerren, A.; Freedman, E. G.

10.1101/2023.06.20.545763 — neuroscience — Posted on 2023-06-24

1110 Inactivation of face selective neurons alters eye movements when free viewing faces

Azadi, R.; Lopez, E.; Taubert, J.; Patterson, A.; Afraz, A.

10.1101/2023.06.20.544678 — neuroscience — Posted on 2023-06-24

1111 Arrhythmogenic Ca2+ Signaling in a Metabolic Model of HFpEF

Kaplan, A. D.; Boyman, L.; Ward, C. W.; Lederer, W. J.; Greiser, M.

10.1101/2023.06.21.544411 — physiology — Posted on 2023-06-24

1112 FLOP: Tasks for Fitness Landscapes Of Protein wildtypes

Groth, P. M.; Michael, R.; Salomon, J.; Tian, P.; Boomsma, W.

10.1101/2023.06.21.545880 — bioinformatics — Posted on 2023-06-24

1113 Pathway Centric Analysis for single-cell RNA-seq and Spatial Transcriptomics Data with GSDensity

Liang, Q.; Huang, Y.; He, S.; Chen, K.

10.1101/2023.06.21.546022 — bioinformatics — Posted on 2023-06-24

1114 SEGMENTATION OF DYNAMIC TOTAL-BODY -FDG PET IMAGES USING UNSUPERVISED CLUSTERING

Jaakkola, M. K.; Rantala, M.; Jalo, A.; Saari, T.; Hentila, J.; Helin, J. S.; Nissinen, T. A.; Eskola, O.; Rajander, J.; Virtanen, K. A.; Hannukainen, J. C.; Lopez-Picon, F.; Klen, R.

10.1101/2023.06.20.545535 — bioinformatics — Posted on 2023-06-24

1115 Spatial decomposition of ultrafast ultrasound images to identify motor unit activity - A validation study using intramuscular and surface EMG

Rohlen, R.; Lubel, E.; Grandi Sgambato, B.; Antfolk, C.; Farina, D.

10.1101/2023.06.21.545924 — bioengineering — Posted on 2023-06-24

1116 Extensive profiling of transcription factors in postmortem brains defines genomic occupancy in disease-relevant cell types and links TF activities to neuropsychiatric disorders

Loupe, J. M.; Anderson, A. G.; Rizzardi, L. F.; Rodriguez-Nunez, I.; Moyers, B.; Trausch-Lowther, K.; Jain, R.; Bunney, W. E.; Bunney, B. G.; Cartagena, P.; Sequeira, A.; Watson, S. J.; Akil, H.; Cooper, G. M.; Myers, R. M.

10.1101/2023.06.21.545934 — genomics — Posted on 2023-06-24

1117 Integration of eQTL and Machine Learning Methods to Dissect Causal Genes with Pleiotropic effects in Genetic Regulation Networks of Seed Cotton Yield

Zhao, T.; Wu, H.; Wang, X.; Zhao, Y.; Wang, L.; Pan, J.; Wang, S.; Han, J.; Mei, H.; Lu, K.; Li, M.; Gao, M.; Cao, Z.; Zhang, H.; Wan, K.; Li, J.; Zhang, T.; Guan, X.

10.1101/2023.06.20.545658 — genetics — Posted on 2023-06-24

1118 A systematic approach identifies p53-DREAM target genes associated with blood or brain abnormalities

Toledo, F.; Rakotopare, J.; Lejour, V.; Duval, C.; Eldawra, E.; Escoffier, H.

10.1101/2023.06.21.545932 — genetics — Posted on 2023-06-24

1119 Strong epistasis constrains the evolution of strict substrate specificity in apicomplexan lactate dehydrogenases

Wirth, J. D.; Boucher, J. I.; Xu, C.; Classen, S.; Theobald, D. L.

10.1101/2023.06.21.545977 — evolutionary biology — Posted on 2023-06-24

1120 Starvation reduces thermal limits of the widespread copepod Acartia tonsa

Rueda Moreno, G.; Sasaki, M. C.

10.1101/2023.06.20.545723 — ecology — Posted on 2023-06-24

1121 The impact of within-host coinfection interactions on between-host parasite transmission dynamics varies with spatial scale

Keegan, S. P.; Pedersen, A. B.; Fenton, A.

10.1101/2023.06.21.545944 — ecology — Posted on 2023-06-24

1122 Pesticide-induced resurgence of the brown planthopper is mediated by diverse actors that promote juvenile hormone biosynthesis and female fecundity

Gao, Y.; Su, S.-C.; Liu, Z.-Y.; Dick, N.; Bass, C.; Gao, C.-F.; Wu, S.-F.

10.1101/2023.06.21.545881 — ecology — Posted on 2023-06-24

1123 Scalable phylogenetic Gaussian process models improve the detectability of environmental signals on extinction risks for many Red List species

Matsuba, M.; Fukasawa, K.; Aoki, S.; Akasaka, M.; Ishihama, F.

10.1101/2023.06.21.545976 — ecology — Posted on 2023-06-24

1124 Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway

Yan, H.; Liu, Y.; Li, X.; Yu, B.; He, J.; Mao, X.; Yu, J.; Huang, Z.; Luo, Y.; Luo, J.; Wu, A.; Chen, D.

10.1101/2023.06.21.546014 — immunology — Posted on 2023-06-24

1125 Brain Metabolic Network Covariance and Aging in a Mouse Model of Alzheimer's Disease

Chumin, E. J.; Burton, C.; Silvola, R.; Persohn, S. C.; Veronese, M.; Territo, P. R.

10.1101/2023.06.21.545918 — neuroscience — Posted on 2023-06-24

1126 Sustained polyphasic sleep restriction abolishes human growth hormone release

Rosenblum, Y.; Weber, F. D.; Rak, M.; Zavecz, Z.; Kunath, N.; Breitenstein, B.; Rasch, B.; Zeising, M.; Uhr, M.; Steiger, A.; Dresler, M.

10.1101/2023.06.20.542775 — neuroscience — Posted on 2023-06-24

1127 Biophysical neural adaptation mechanisms enable deep learning models to capture dynamic retinal computation

Idrees, S.; Rieke, F.; Field, G. D.; Zylberberg, J.

10.1101/2023.06.20.545728 — neuroscience — Posted on 2023-06-24

1128 Entropy predicts early MEG, EEG and fMRI responses to natural images

Muukkonen, I.; Salmela, V. R.

10.1101/2023.06.21.545883 — neuroscience — Posted on 2023-06-24

1129 Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice

Boyd, S. L.; Kuhn, N. C.; Patterson, J. R.; Stoll, A. C.; Zimmerman, S. A.; Kolanowski, M. R.; Neubecker, J. J.; Luk, K. C.; Ramsson, E. S.; Sortwell, C. E.; Bernstein, A. I.

10.1101/2023.06.21.545967 — neuroscience — Posted on 2023-06-24

1130 Probing the neurophysiology of temporal sensitivity in the somatosensory system using the mismatch negativity (MMN) sensory memory paradigm.

Isenstein, E.; Freedman, E. G.; Xu, A. J.; DeAndrea-Lazarus, I.; Foxe, J. J.

10.1101/2023.06.21.545720 — neuroscience — Posted on 2023-06-24

1131 Neural circuits for fast Poisson compressed sensing in the olfactory bulb

Zavatone-Veth, J. A.; Masset, P.; Tong, W. L.; Zak, J. D.; Murthy, V. N.; Pehlevan, C.

10.1101/2023.06.21.545947 — neuroscience — Posted on 2023-06-24

1132 Evidence for glutamate excitotoxicity that occurs before the onset of cell loss and motor symptoms in an ovine Huntington's Disease model.

Jiang, A.; Lehnert, K.; You, L.; Hawkins, V.; Reid, S. J.; Handley, R. R.; Jacobsen, J. C.; Patassini, S.; Rudiger, S. R.; McLaughlan, C. J.; Kelly, J. M.; Verma, P. J.; Bawden, C. S.; Gusella, J. F.; MacDonald, M. E.; Waldvogel, H. J.; Faull, R. L. M.; Snell, R. G.

10.1101/2023.06.20.545648 — neuroscience — Posted on 2023-06-24

1133 The impact of ROI extraction method for MEG connectivity estimation: practical recommendations for the study of resting state data.

Brkic, D.

10.1101/2023.06.20.545792 — neuroscience — Posted on 2023-06-24

1134 Vascular Endothelial Barrier Protection Prevents Atrial Fibrillation by Preserving Cardiac Nanostructure

Mezache, L.; Soltisz, A. M.; Johnstone, S. R.; Isakson, B. E.; Veeraraghavan, R.

10.1101/2023.06.20.545742 — physiology — Posted on 2023-06-24

1135 Metabolic transitions regulate global protein fatty acylation

Talwadekar, M.; Khatri, S.; Balaji, C.; Chakraborty, A.; Basak, N.-P.; Kamat, S.; Kolthur-Seetharam, U.

10.1101/2023.06.20.545712 — physiology — Posted on 2023-06-24

1136 Hip thrust and back squat training elicit similar gluteus muscle hypertrophy and transfer similarly to the deadlift

Plotkin, D. L.; Rodas, M. A.; Vigotsky, A.; McIntosh, M. C.; Breeze, E.; Ubrik, R.; Robitzsch, C.; Agyin-Birikorang, A.; Mattingly, M. L.; Michel, J. M.; Kontos, N. J.; Fruge, A. D.; Wilborn, C. M.; Weimar, W. H.; Bashir, A.; Beyers, R. J.; Henselmans, M.; Contreras, B. M.; Roberts, M. D.

10.1101/2023.06.21.545949 — physiology — Posted on 2023-06-24

1137 Cardiomyocytes Deficiency of SENP1 Promotes Myocardial Fibrosis via Paracrine Action

Liu, Z.

10.1101/2023.06.21.546019 — pathology — Posted on 2023-06-24

1138 A Clear, Legible, Explainable, Transparent, and Elucidative (CLETE) Binary Classification Platform for Tabular Data

Nasimian, A.; Younus, S.; Hammarlund, E. U.; Pienta, K. J.; Rönnstrand, L.; Kazi, J. U.

10.1101/2023.06.20.545752 — bioinformatics — Posted on 2023-06-24

1139 Co-linear Chaining on Pangenome Graphs

Rajput, J.; Chandra, G.; Jain, C.

10.1101/2023.06.21.545871 — bioinformatics — Posted on 2023-06-24

1140 Exact Sketch-Based Read Mapping

Schulz, T.; Medvedev, P.

10.1101/2023.06.21.545862 — bioinformatics — Posted on 2023-06-24

1141 QuantUMS: uncertainty minimisation enables confident quantification in proteomics

Kistner, F.; Grossmann, J. L.; Sinn, L. R.; Demichev, V.

10.1101/2023.06.20.545604 — bioinformatics — Posted on 2023-06-24

1142 A method for storing information in DNA with improved dropout tolerance

Mortuza, G. M.; Tobiason, M. D.; Suyehira, K.; Hughes, W. L.; Andersen, T.; Zadegan, R.

10.1101/2023.06.20.545769 — bioinformatics — Posted on 2023-06-24

1143 Brooklyn plots to identify co-expression dysregulation in single cell sequencing

Patil, A. H.; Halushka, M. K.

10.1101/2023.06.21.545951 — bioinformatics — Posted on 2023-06-24

1144 Trajectories of atherosclerotic cardiovascular disease risk scores as a predictor for incident chronic kidney disease

Lee, H. S.; Lim, H. I.; Moon, T. J.; Lee, S. Y.; Lee, J.-H.

10.1101/2023.06.20.545824 — bioinformatics — Posted on 2023-06-24

1145 RIBO-former: leveraging ribosome profiling information to improve the detection of translated open reading frames.

Clauwaert, J.; McVey, Z.; Gupta, R.; Menschaert, G.

10.1101/2023.06.20.545724 — bioinformatics — Posted on 2023-06-24

1146 Fractional Hitting Sets for Efficient and Lightweight Genomic Data Sketching

Rouze, T.; Martayan, I.; MARCHET, C.; Limasset, A.

10.1101/2023.06.21.545875 — bioinformatics — Posted on 2023-06-24

1147 Multi_CycGT: a DL-based multimodal model for membrane permeability prediction of cyclic peptides

Cao, l.; Xu, z.; Zhang, c.; Shang, t.; Wu, x.; Wu, y.; Zhai, s.; Ma, l.; duan, h.

10.1101/2023.06.20.545822 — bioinformatics — Posted on 2023-06-24

1148 A 128-ch area-efficient neurochemical-sensing front-end for FSCV recordings of dopamine

White, K. A.; Darroudi, M.; Park, J.; Kim, B. N.

10.1101/2023.06.20.545834 — bioengineering — Posted on 2023-06-24

1149 Kinetic and functional analysis of abundant microRNAs in extracellular vesicles from normal and stressed cultures of Chinese Hamster Ovary (CHO) cells

Belliveau, J.; Thompson, W.; Papoutsakis, E. T.

10.1101/2023.06.21.545902 — bioengineering — Posted on 2023-06-24

1150 A model-based hypothesis framework to define and estimate the diel niche via the 'Diel.Niche' R package

Gerber, B. D.; Devarajan, K.; Farris, Z. J.; Fidino, M.

10.1101/2023.06.21.545898 — animal behavior and cognition — Posted on 2023-06-24

1151 Detecting Full-Length EccDNA with FLED and long-reads sequencing

Li, F.; Ming, W.; Lu, W.; Wang, Y.; Li, X.; Dong, X.; Bai, Y.

10.1101/2023.06.21.545840 — genomics — Posted on 2023-06-24

1152 A case study of Whirly1 (WHY1) evolution in the angiosperms: altered sequence, splicing, and expression in a clade of early-transitional mycoheterotrophic orchids

Muti, R. M.; Barrett, C. F.; Sinn, B. T.

10.1101/2023.06.21.545690 — evolutionary biology — Posted on 2023-06-24

1153 The geography of metacommunities: landscape characteristics drive geographic variation in the assembly process through selecting species pool attributes

Khattar, G.; Peres-Neto, P.

10.1101/2023.06.20.545715 — ecology — Posted on 2023-06-24

1154 Assembly processes of bacterial and fungal community differ between desert and oasis habitats in an arid inland river basin, northwest China

Wang, W.-J.; Ding, Y.-M.; Ren, M.-X.; Li, J.-W.

10.1101/2023.06.21.545439 — ecology — Posted on 2023-06-24

1155 SR-BI regulates the synergistic mast cell response by modulating the plasma membrane-associated cholesterol pool

Capellmann, S.; Kauffmann, M.; Arock, M.; Huber, M.

10.1101/2023.06.21.545859 — immunology — Posted on 2023-06-24

1156 Blood flow directionality establishes the SCN as source and OVLT as target within a new vascular portal pathway

Roy, R. K.; Yao, Y.; Green, I. K.; Silver, R.; Stern, J. E.

10.1101/2023.06.20.545729 — neuroscience — Posted on 2023-06-24

Klickstein, J. A.; Johnson, M. A.; Antonoudiou, P.; Maguire, J.; Paulo, J.; Gygi, S.; Weihl, C. C.; Raman, M.

10.1101/2023.06.21.545956 — neuroscience — Posted on 2023-06-24

1158 In vivo visualization of intracellular pH gradient in brain using PET imaging

Yamasaki, T.; Mori, W.; Ohkubo, T.; Hiraishi, A.; Zhang, Y.; Kurihara, Y.; Nengaki, N.; Tashima, H.; Fujinaga, M.; Zhang, M.-R.

10.1101/2023.06.21.546029 — neuroscience — Posted on 2023-06-24

1159 Non-Consummatory Behavior Signals Predict Aversion-Resistant Alcohol Drinking in Head-Fixed Mice

Timme, N.; Ardinger, C.; Weir, S. D. C.; Zelaya-Escobar, R.; Kruger, R.; Lapish, C. C.

10.1101/2023.06.20.545767 — neuroscience — Posted on 2023-06-24

1160 Structural neuroplasticity after sleep loss modifies behavior and requires neurexin and neuroligin

Cowen, M. H.; Raizen, D. M.; Hart, M. P.

10.1101/2023.06.20.545788 — neuroscience — Posted on 2023-06-24

1161 Astrocytes gate long-term potentiation in hippocampal interneurons

Shen, W.; Tang, Y.; Yang, J.; Zhu, L.; Zhou, W.; Xiang, L.; Zhu, F.; Dong, J.; Xie, Y.; Zeng, L.-H.

10.1101/2023.06.20.545820 — neuroscience — Posted on 2023-06-24

1162 Network States in the Basolateral Amygdala Predicts Voluntary Alcohol Consumption

DiLeo, A.; Antonoudiou, P.; Conlin, E.; Melon, L.; Maguire, J.

10.1101/2023.06.21.545962 — neuroscience — Posted on 2023-06-24

1163 The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation

Elorette, C.; Fujimoto, A.; Stoll, F. M.; Fujimoto, S. H.; Fleysher, L.; Bienkowska, N.; Russ, B. E.; Rudebeck, P.

10.1101/2023.06.21.545778 — neuroscience — Posted on 2023-06-24

1164 BrainProt(™) 3.0: Understanding Human Brain Diseases using comprehensively curated & Integrated OMICS datasets

Biswas, D.; Shenoy, S. V.; Chauhan, A.; Halder, A.; Ghosh, B.; Padhye, A.; Auromahima, S.; Yadav, D.; Sasmal, S.; Dutta, S.; Kumari, N.; Bavaskar, H.; Mukherjee, A. P.; Kumar, T. R.; Srivastava, S.

10.1101/2023.06.21.545851 — neuroscience — Posted on 2023-06-24

1165 1LocusSim a mobile-friendly simulator for teaching population genetics

Carvajal-Rodriguez, A.

10.1101/2023.06.20.545745 — scientific communication and education — Posted on 2023-06-24

1166 Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling

Das, P.; Aballay, A.; Singh, J.

10.1101/2023.06.21.545873 — physiology — Posted on 2023-06-24

1167 Activation of Shh/Smo is sufficient to maintain oligodendrocyte precursor cells in an undifferentiated state but is not necessary for differentiation

Nocera, S.; Marchena, M. A.; Fernandez-Gomez, B.; Lao, Y.; Cordano, C.; Gomez-Torres, O.; Lujan, R.; de Castro, F.

10.1101/2023.06.23.546285 — neuroscience — Posted on 2023-06-23

1168 Metabolic and Neurobehavioral Disturbances Induced by Purine Recycling Deficiency in Drosophila

Petitgas, C.; Seugnet, L.; Dulac, A.; Mteyrek, A.; Fima, R.; Strehaiano, M.; Dagorret, J.; Cherif-Zahar, B.; Marie, S.; Ceballos-Picot, I.; Birman, S.

10.1101/2023.06.23.546306 — neuroscience — Posted on 2023-06-23

1169 Bayesian analysis dissects kinetic modulation during non-stationary gene expression

Wildner, C.; Ball, D. A.; Mehta, G. D.; Karpova, T. S.; Koeppl, H.

10.1101/2023.06.20.545522 — systems biology — Posted on 2023-06-23

1170 A Functional Data Analysis Approach to RuBisCO Engineering

McCormack, A. C.

10.1101/2023.06.14.544690 — synthetic biology — Posted on 2023-06-23

1171 Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles

Hannon, E.; Dempster, E. L.; Chioza, B.; Davies, J. P.; Blake, G. E.; Burrage, J.; Policicchio, S.; Franklin, A.; Walker, E. M.; Bamford, R. A.; Schalkwyk, L. C.; Mill, J.

10.1101/2023.06.23.545974 — genomics — Posted on 2023-06-23

1172 Longitudinal development of thalamocortical functional connectivity in 22q11.2 deletion syndrome

Schleifer, C. H.; O'Hora, K. P.; Jalbrzikowski, M.; Bondy, E.; Kushan-Wells, L.; Lin, A.; Uddin, L. Q.; Bearden, C. E.

10.1101/2023.06.22.546178 — neuroscience — Posted on 2023-06-23

1173 Koalas, cameras and a primary school: Obtaining ecological insights for land management through a mini-citizen science project with young students.

Williams, S. B.; Salmon, G.; Dempsey, D.; Philpot, D.; Faulkner, G. B.

10.1101/2023.06.22.546188 — scientific communication and education — Posted on 2023-06-23

1174 Demographic and genetic impacts of powdery mildew in a young oak cohort

Barres, B.; Dutech, C.; Saint-Jean, G.; Bodenes, C.; Burban, C.; Fievet, V.; Lepoittevin, C.; Garnier-Gere, P.; Desprez-Loustau, M.-L.

10.1101/2023.06.22.546164 — plant biology — Posted on 2023-06-23

1175 Type III-B CRISPR-Cas signaling-based cascade of proteolytic cleavages

Steens, J.; Bravo, J. P.; Salazar, C. R. P.; Yildiz, C.; Amieiro, A. M.; Kostlbacher, S.; Prinsen, S. H. P.; Patinios, C.; Bardis, A.; Barendrecht, A.; Scheltema, R. A.; Ettema, T. J. G.; van der Oost, J.; Taylor, D. W.; Staals, R.

10.1101/2023.06.23.546230 — biochemistry — Posted on 2023-06-23

1176 Cross-linking mass spectrometric analysis of the endogenous TREX complex from S. cerevisiae

Kern, C.; Radon, C.; Wende, W.; Leitner, A.; Straesser, K.

10.1101/2023.06.23.546279 — biochemistry — Posted on 2023-06-23

1177 Genome-wide identification of silencers in human cells

Zhu, X.; Wang, C.; Kong, D.; Luo, J.; Deng, B.; Gu, Y.; Kong, S.; Huang, L.; Liu, Y.; Zhang, Y.

10.1101/2023.06.20.545673 — genomics — Posted on 2023-06-23

1178 N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs

Lee, E. S.; Scalize de Olivera, L.; Jomphe, R. Y.; Ihn, S. S.; Smith, H. W.; Nabeel-Shah, S.; Pu, S.; Greenblatt, J. F.; Palazzo, A. F.

10.1101/2023.06.20.545713 — molecular biology — Posted on 2023-06-21

1179 A sex-specific homologue of snake waprin is required for embryonic development in the Red Flour Beetle, Tribolium castaneum

Choudhary, C.; Sharma, S.; Meghwanshi, K. K.; Kishore, D.; Verma, V.; Shukla, J. N. S.

10.1101/2023.06.21.545995 — molecular biology — Posted on 2023-06-21

1180 Holobiont Evolution: Lytic/Lysogenic Transition as a Life-History Switch

Roughgarden, J.

10.1101/2023.01.03.522622 — evolutionary biology — Posted on 2023-06-23

1181 Biomarkers to predict steroid resistance in idiopathic nephrotic syndrome: a systematic review.

May, C. J.; Ford, N. P.

10.1101/2023.06.21.545865 — molecular biology — Posted on 2023-06-21

1182 Dissecting genetic correlation through recombinant perturbations: the role of developmental bias

Cai, H.; Geiler-Samerotte, K.; Des Marais, D. L.

10.1101/2023.05.12.540583 — evolutionary biology — Posted on 2023-06-23

1183 Abundant capped RNAs are derived from mRNA cleavage at 3'UTR G-Quadruplexes

Haberman, N.; Digby, H.; Faraway, R.; Cheung, R.; Jobbins, A. M.; Parr, C.; Yasuzawa, K.; Kasukawa, T.; Yip, C. W.; Kato, M.; Takahashi, H.; Carninci, P.; Vernia, S.; Ule, J.; Sibley, C. R.; Martinez-Sanchez, A.; Lenhard, B.

10.1101/2023.04.27.538568 — molecular biology — Posted on 2023-06-22

1184 Genome-scale community modelling reveals conserved metabolic cross-feedings in epipelagic bacterioplankton communities

Giordano, N.; Gaudin, M.; Trottier, C.; Delage, E.; Nef, C.; Bowler, C.; Chaffron, S.

10.1101/2023.06.21.545869 — ecology — Posted on 2023-06-23

1185 Roadmap For The Expression Of Canonical and Extended Endocannabinoid System Receptors and Proteins in Peripheral Organs of Preclinical Animal Models

Rosado-Franco, J. J.; Ellison, A. L.; White, C. J.; Price, A. S.; Moore, C. F.; Williams, R. E.; Fridman, L. B.; Weerts, E. M.; Williams, D. W.

10.1101/2023.06.10.544455 — molecular biology — Posted on 2023-06-22

1186 Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes

Milenkovic, D.; Misic, J.; Hevler, J. F.; Molinie, T.; Chung, I.; Atanassov, I.; Li, X.; Filograna, R.; Mesaros, A.; Mourier, A.; Heck, A. J. R.; Hirst, J.; Larsson, N.-G.

10.1101/2023.06.19.545560 — molecular biology — Posted on 2023-06-22

1187 Identification of fish spawning based on size-selected sampling and diurnal concentration changes of environmental DNA resulting from sperm-release

Tsuji, S.; Shibata, N.

10.1101/2023.06.19.545639 — molecular biology — Posted on 2023-06-22

1188 Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos

Fan, J.; Kang, B. G.; Kam, T.-I.; Behensky, A.; Rines, J.; Kang, H. C.; Dawson, V. L.; Dawson, T.

10.1101/2023.06.18.545460 — cell biology — Posted on 2023-06-23

1189 Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils

Jeppsson, K.; Pradhan, B.; Sutani, T.; Sakata, T.; Umeda Igarashi, M.; Berta, D. G.; Kanno, T.; Nakato, R.; Shirahige, K.; Kim, E.; Bjorkegren, C.

10.1101/2023.06.20.545053 — molecular biology — Posted on 2023-06-22

1190 Reversal of carbapenem resistance in Pseudomonas aeruginosa by camelid single domain antibody fragment (VHH) against the C4 dicarboxylate transporter

Nagraj, A. K.; Kulkarni, M.; Shukla, M.; Patil, P.; Borgave, M.; BANERJEE, S. K.

10.1101/2023.06.20.545680 — molecular biology — Posted on 2023-06-22

1191 The widespread influence of ZSWIM8 on microRNAs during mouse embryonic development

Shi, C.; Elcavage, L.; Chivukula, R.; Stefano, J.; Kleaveland, B.; Bartel, D.

10.1101/2023.06.21.545803 — molecular biology — Posted on 2023-06-22

1192 DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor

Pandiloski, N.; Horvath, V.; Karlsson, O. E.; Christoforidou, G.; Dorazehi, F.; Koutounidou, S.; Matas, J.; Gerdes, P.; Garza, R.; Jönsson, M. E.; Adami, A.; Atacho, D.; Johansson, J. G.; Englund, E.; Kokaia, Z.; Jakobsson, J.; Douse, C. H.

10.1101/2023.06.21.545516 — molecular biology — Posted on 2023-06-22

1193 RAS G-domains fine-tune the sorting of phosphatidylserine acyl chains in the plasma membrane

Arora, N.; Liang, H.; Zhou, Y.

10.1101/2023.06.20.545612 — molecular biology — Posted on 2023-06-22

1194 Boosting class II HLA epitope presentation to T cells with endoplasmic reticulum transmembrane domain fusion proteins

Pinamonti, V.; Mellado Fuentes, A.; Schmid, T.; Cetin, M.; Lerner, T.; Hernandez Hernandez, M.; Lindner, J. M.

10.1101/2023.06.22.546056 — molecular biology — Posted on 2023-06-22

1195 Mitogenome fragmentation evolves multiple times within a major group of parasitic lice

Najer, T.; Dona, J.; Bucek, A.; Sweet, A. D.; Sychra, O.; Johnson, K. P.

10.1101/2023.06.22.546119 — molecular biology — Posted on 2023-06-22

1196 Molecular pathway of mitochondrial preprotein import through the TOM-TIM23

Zhou, X.; Yang, Y.; Wang, G.; Wang, S.; Sun, D.; Ou, X.; Lian, Y.; Li, L.

10.1101/2023.06.21.546012 — molecular biology — Posted on 2023-06-22

1197 The influence of diet on gut microbiome and body mass dynamics in a capital-breeding migratory bird

Jones, I. L.; Marsh, K.; Handby, T.; Hopkins, K.; Slezacek, J.; Bearhop, S.; Harrison, X.

10.1101/2023.06.22.546090 — molecular biology — Posted on 2023-06-22

1198 Loss of endothelial cell heterogeneity in arteries after obesogenic diet

Dunaway, L. S.; Luse, M. A.; Nyshadham, S.; Bulut, G.; Alencar, G. F.; Chavkin, N. W.; Cortese-Krott, M.; Hirschi, K. K.; Isakson, B. E.

10.1101/2023.06.23.546320 — molecular biology — Posted on 2023-06-23

1199 Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target-silencing

Li, Z.; Li, Z.; Li, L.; Zeng, L.; Xue, J.; Niu, H.; Zhong, J.; Yu, Q.; Li, D.; Tu, S.; Zhang, Z.; Song, C.-Q.; Wu, J.; Shen, E.-Z.

10.1101/2023.06.23.546240 — molecular biology — Posted on 2023-06-23

1200 The Role of Respiratory Complex IV in Lifespan Length and Quality

Castejon-Vega, B.; Fernandez-Guerrero, I.; Myers, K.; Kataura, T.; Stefanatos, R.; Korolchuk, V. I.; Sanz, A.

10.1101/2023.06.23.546283 — molecular biology — Posted on 2023-06-23

1201 Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile

Filippopoulou, C.; Thome, C. C.; Perdikari, S.; Ntini, E.; Simos, G.; Bohnsack, K. E.; Chachami, G.

10.1101/2023.06.23.546038 — molecular biology — Posted on 2023-06-23

1202 Corepressor inactivation through tandem linear motif-induced polymerization

Goradia, N.; Werner, S.; Mullapudi, E.; Greimeier, S.; Merkens, L.; Lang, A.; Mertens, H. D. T.; Weglarz, A.; Sander, S.; Chojnowski, G.; Wikman, H.; Ohlenschlaeger, O.; von Amsberg, G.; Pantel, K.; Wilmanns, M.

10.1101/2023.06.16.545227 — molecular biology — Posted on 2023-06-23

1203 PCR data accurately predict infectious virus: a characterization of SARS-CoV-2 in non-human primates

Snedden, C. E.; Lloyd-Smith, J. O.

10.1101/2023.06.23.546114 — microbiology — Posted on 2023-06-23

1204 Rarefaction is currently the best approach to control for uneven sequencing effort in amplicon sequence analyses

Schloss, P. D.

10.1101/2023.06.23.546313 — microbiology — Posted on 2023-06-23

1205 Contrasting genes conferring short and long-term biofilm adaptation in Listeria

Monteith, W.; Pascoe, B.; Mourkas, E.; Clark, J. L.; Hakim, M.; Hitchings, M. D.; McCarthy, N.; Yahara, K.; Asakura, H.; Sheppard, S.

10.1101/2023.06.22.546149 — microbiology — Posted on 2023-06-23

1206 Evasion of APOBEC1-mediated Intrinsic Immunity by a Herpesvirus Uracil DNA Glycosylase Is a Determinant of Viral Encephalitis

Kato, A.; Harima, H.; Tsunekawa, Y.; Igarashi, M.; Kitamura, K.; Wakae, K.; Kozuka-Hata, H.; Oyama, M.; Watanabe, M.; Takeshima, K.; Maruzuru, Y.; Koyanagi, N.; Okada, T.; Muramatsu, M.; Kawaguchi, Y.

10.1101/2023.06.22.546204 — microbiology — Posted on 2023-06-23

1207 The great divide: rhamnolipids mediate separation between P. aeruginosa and S. aureus

Bru, J.-L.; Kasallis, S. J.; Chang, R.; Zhuo, Q.; Nguyen, J.; Pham, P.; Warren, E.; Whiteson, K.; Hoyland-Kroghsbo, N. M.; Limoli, D. H.; Siryaporn, A.

10.1101/2023.06.23.546300 — microbiology — Posted on 2023-06-23

1208 Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans

Benz, F.; Camara-Wilpert, S.; Russel, J.; Wandera, K. G.; Cepaite, R.; Ares-Arroyo, M.; Gomes-Filho, J. V.; Englert, F.; Kuehn, J.; Gloor, S.; Cuenod, A.; Aguila-Sans, M.; Maccario, L.; Egli, A.; Randau, L.; Pausch, P.; Rocha, E.; Beisel, C. L.; Madsen, J. S.; Bikard, D.; Hall, A. R.; Soerensen, S. J.; Pinilla-Redondo, R.

10.1101/2023.06.23.546257 — microbiology — Posted on 2023-06-23

1209 Gestational diabetes augments group B Streptococcus perinatal infection through disruptions in maternal immunity and the vaginal microbiota

Mercado-Evans, V.; Mejia, M. E.; Zulk, J. J.; Ottinger, S.; Hameed, Z.; Serchejian, C.; Marunde, M. G.; Robertson, C. M.; Ballard, M. B.; Korotkova, N.; Flores, A.; Pennington, K. A.; Patras, K. A.

10.1101/2023.06.23.546252 — microbiology — Posted on 2023-06-23

1210 Development of a computational model to inform environmental surveillance sampling plans for Salmonella enterica serovar Typhi in wastewater

Burnor, E.; Morin, C.; Shirai, J.; Zhou, N.; Meschke, J. S.

10.1101/2023.06.22.545856 — microbiology — Posted on 2023-06-23

1211 Determination of Accumulation of Molecules in Escherichia coli

Ongwae, G. M.; Liu, Z.; Chordia, M. D.; Guo, T.; Dong, J.; Pires, M.; Dalesandro, B. E.

10.1101/2023.06.20.545103 — microbiology — Posted on 2023-06-23

1212 The F pilus serves as a conduit for the DNA during conjugation between physically distant bacteria

Goldlust, K.; Ducret, A.; Halte, M.; Dedieu-Berne, A.; Erhardt, M.; Lesterlin, C.

10.1101/2023.06.21.545889 — microbiology — Posted on 2023-06-23

1213 The contribution of abortive infection to preventing populations of Lactococcus lactis from succumbing to infections with bacteriophage

Rodriguez-Roman, E.; Manuel, J. A.; Goldberg, D. A.; Levin, B. R.

10.1101/2023.06.23.546325 — microbiology — Posted on 2023-06-23

1214 Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium

Guan, J.; Peske, J. D.; Manoharan Valerio, M.; Park, C.; Robey, E. A.; Sadegh-Nasseri, S.; Shastri, N.

10.1101/2023.03.01.530600 — immunology — Posted on 2023-06-23

1215 Tracking components of bilingual language control in speech production: an fMRI study using functional localizers.

Wolna, A.; Szewczyk, J.; Diaz, M.; Domagalik, A.; Szwed, M.; Wodniecka, Z.

10.1101/2023.02.07.527469 — neuroscience — Posted on 2023-06-23

1216 Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for normal breathing and chemosensory reflexes

Chang, Y.; Lusk, S.; Ray, R.

10.1101/2023.04.16.535729 — neuroscience — Posted on 2023-06-23

1217 Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions

Gao, Y.; Trn, M.; Shonai, D.; Zhao, J.; Soderblom, E. J.; Garcia-moreno, S. A.; Gersbach, C. A.; Wetsel, W. C.; Dawson, G.; Velmeshev, D.; Jiang, Y.-h.; Sloofman, L. G.; Buxbaum, J.; Soderling, S. H.

10.1101/2022.10.06.511211 — neuroscience — Posted on 2023-06-23

1218 Task feedback suggests a post-perceptual component to serial dependence

Fulvio, J. M.; Rokers, B.; Samaha, J.

10.1101/2022.03.19.484939 — neuroscience — Posted on 2023-06-23

1219 Hippocampal place cell remapping occurs with memory storage of aversive experiences

Blair, G. J.; Guo, C.; Wang, S.; Fanselow, M.; Golshani, P.; Aharoni, D.; Blair, H. T.

10.1101/2022.05.26.493592 — neuroscience — Posted on 2023-06-23

1220 Control of stem cell behavior by CLE-JINGASA signaling in the shoot apical meristem in Marchantia polymorpha

Takahashi, G.; Kiyosue, T.; Hirakawa, Y.

10.1101/2023.06.23.545176 — plant biology — Posted on 2023-06-23

1221 High prevalence of haemosporidian parasites in Eurasian Jays

Schumm, Y. R.; Lederer-Ponzer, N.; Masello, J. F.; Quillfeldt, P.

10.1101/2023.06.20.545710 — pathology — Posted on 2023-06-23

1222 The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancer

Armaos, A.; Serra, F.; Nunez Carpintero, I.; Seo, J. H.; Baca, S. C.; Gustincich, S.; Valencia, A.; Freedman, M. L.; Cirillo, D.; Giambartolomei, C.; Tartaglia, G. G.

10.1101/2022.10.20.512998 — cancer biology — Posted on 2023-06-22

1223 Tumor-derived exosomal miR-222-3p induce cancer-associated fibroblasts activation to foster progression of renal cancer

Yang, Y.; Zhu, J.; Shen, D. L.; Han, C.; Wang, C. F.; Cui, B.; Fan, W. M.; Huang, Y.; Li, X. B.; Zhang, X.; Gao, Y.

10.1101/2023.06.22.546057 — cancer biology — Posted on 2023-06-22

1224 INDOCYANINE GREEN IMAGING BY VITAL TISSUE SLICES SCANNING ALLOWS FOR THE ISOLATION OF INTACT LIVER MICRO-METASTASIS FOR SINGLE-CELL ANALYSIS

Roda, N.; Stendardo, M.; Gambino, V.; Persico, G.; Cossa, A.; Rodighiero, S.; Priami, C.; Kaludercic, N.; Pelicci, P. G.; Giorgio, M.

10.1101/2023.06.21.545927 — cancer biology — Posted on 2023-06-22

1225 Lack of detectable neoantigen depletion in treatment-naive cancers

Slagter, M.; Fanchi, L.; van Buuren, M. M.; Velds, A.; Bounova, G.; Wessels, L.; Schumacher, T.

10.1101/2023.06.21.544805 — cancer biology — Posted on 2023-06-22

1226 The Chicken Chorioallantoic Membrane as a Low-Cost, High-Throughput Model for Cancer Imaging

Smith, L. M.; Greenwood, H. E.; Tyrrell, W. E.; Edwards, R. S.; de Santis, V.; Baark, F.; Firth, G.; Tanc, M.; Terry, S. Y. A.; Herrmann, A.; Southworth, R.; Witney, T. H.

10.1101/2023.06.21.545917 — cancer biology — Posted on 2023-06-22

1227 Tirzepatide inhibits tumor growth in mice with diet-induced obesity

Huang, L.; Zeng, J.; Wang, Y.; Pollak, M.

10.1101/2023.06.22.546093 — cancer biology — Posted on 2023-06-22

1228 FSCN1 is critical for HNSCC

Wei, X.

10.1101/2023.06.20.545739 — cancer biology — Posted on 2023-06-22

1229 Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging.

Pulfer, A.; Pizzagalli, D. U.; Gagliardi, P. A.; Hinderling, L.; Lopez, P.; Zayats, R.; Barbera, P. C.; Antonello, P.; Segura, M. P.; Giusti, A.; Thelen, M.; Gambardella, L. M.; Murooka, T.; Pertz, O.; Krause, R.; Gonzalez, S. F.

10.1101/2022.11.23.517318 — bioinformatics — Posted on 2023-06-23

1230 DESP: Demixing Cell State Profiles from Dynamic Bulk Molecular Measurements

Youssef, A.; Paul, I.; Crovella, M.; Emili, A.

10.1101/2023.01.19.524460 — bioinformatics — Posted on 2023-06-23

1231 HuR-miRNA complex Activates RAS GTPase RalA to Facilitate Endosome Targeting and Extracellular Export of miRNAs

Ghosh, S.; Choudhury, S. H.; Mukherjee, K.; Bhattacharyya, S. N.

10.1101/2023.06.22.546187 — biochemistry — Posted on 2023-06-23

1232 4-Thiaproline accelerates the slow folding phase of proteins containing cis prolines in the native state by two orders of magnitude

O' Loughlin, J.; Zinovjev, K.; Napolitano, S.; Van der Kamp, M.; Rubini, M.

10.1101/2023.06.23.546227 — biochemistry — Posted on 2023-06-23

1233 A conformationally constrained synthetic peptide efficiently inhibits malaria parasite entry into human red blood cells

Biswas, A.; Narayan, A.; Sinha, S.; Mandal, K.

10.1101/2023.06.23.546305 — biochemistry — Posted on 2023-06-23

1234 Structural properties of the HNF-1A transactivation domain

Kind, L.; Driver, M.; Raasakka, A.; Onck, P. R.; Njolstad, P. R.; Arnesen, T.; Kursula, P.

10.1101/2023.06.23.546236 — biochemistry — Posted on 2023-06-23

1235 Microplastics reduce the efficiency of the biological carbon pump by decreasing the settling velocity and carbon content of marine snow

Roberts, C.; Flintrop, C. M.; Khachikyan, A.; Milucka, J.; Munn, C. B.; Iversen, M. H.

10.1101/2023.06.23.545915 — biochemistry — Posted on 2023-06-23

1236 Catalytic bias and redox-driven inactivation of ancestral FeFe hydrogenases from group B

Fasano, A.; Jacq-Bailly, A.; Wozniak, J.; Fourmond, V.; Leger, C.

10.1101/2023.06.23.541094 — biochemistry — Posted on 2023-06-23

1237 Asynchronous haltere input drives specific wing and head movements in Drosophila

Rauscher, M. J.; Fox, J. L.

10.1101/2022.09.29.509061 — animal behavior and cognition — Posted on 2023-06-23

1238 First genome-based characterization of Listeria monocytogenes in Costa Rica

Giralt-Zuniga, M.; Redondo-Solano, M.; Moura, A.; Tessaud-Rita, N.; Bracq-Dieye, H.; Vales, G.; Thouvenot, P.; Leclercq, A.; Chaves-Ulate, C.; Nunez-Montero, K.; Guillen-Watson, R.; Rivas-Solano, O.; Chanto-Chacon, G.; Duarte-Martinez, F.; Soto-Blanco, V.; Pizarro-Cerda, J.; Lecuit, M.

10.1101/2023.06.23.543262 — genomics — Posted on 2023-06-23

1239 Fecal Virome of Southeastern Maned Sloth (Bradypus crinitus)

Coimbra, A.; D'arc, M.; Moreira, F. R. R.; Cosentino, M. A. C.; Schiffler, F. B.; Miranda, T. d. S.; Mouta, R.; Girardi, D. L.; Gomes de Matos, I.; Wanderkoke, V.; Medeiros, G.; Franca, M. L. d. A.; de Oliveira, T. H.; Francisco, T. M.; Soffiati, F. L.; Ferreira, S. S.; Ruiz-Miranda, C. R.; Soares, M. A.; Santos, A. F. A. d.

10.1101/2023.06.23.546151 — genetics — Posted on 2023-06-23

1240 A pair of RNA binding proteins inhibit ion transporter expression to maintain lifespan

Napier-Jameson, R.; Marx, O.; Norris, A. D.

10.1101/2023.05.10.540279 — genetics — Posted on 2023-06-23

1241 Characterization of genetic and molecular tools for studying the endogenous expression of Lactate dehydrogenase in Drosophila melanogaster

Rai, M.; Carter, S. M.; Shefali, S. A.; Chawla, G.; Tennessen, J. M.

10.1101/2023.06.15.545165 — developmental biology — Posted on 2023-06-23

1242 Microbiome remodeling through bacterial competition and host behavior enables rapid adaptation to environmental toxins.

Kim, D. J.; Perez-Carrascal, O. M.; DeSousa, C.; Jung, D. K.; Bohley, S.; Wijaya, L.; Trang, K.; Khoury, S. E.; Shapira, M.

10.1101/2023.06.21.545768 — evolutionary biology — Posted on 2023-06-23

1243 Response of soil microbiome composition to selection on methane oxidation rate

Morris, A. H.; Bohannan, B. J. M.

10.1101/2023.06.23.546315 — ecology — Posted on 2023-06-23

1244 A CDC-42-regulated actin network is necessary for nuclear migration through constricted spaces in C. elegans

Ho, J.; Guerrero, L. A.; Libuda, D. A.; Luxton, G. G.; Starr, D. A.

10.1101/2023.06.22.546138 — developmental biology — Posted on 2023-06-23

1245 Flagellar switch inverted repeat sequence variation impacts Clostridioides difficile RT027/MLST1 virulence.

Nhu, N. T. Q.; Lin, H.; Sia, J. K.; Snitkin, E. S.; Young, V. B.; Kamboj, M.; Pamer, E. G.; Rice, P. A.; Dong, Q.

10.1101/2023.06.22.546185 — microbiology — Posted on 2023-06-23

1246 Infection-induced vascular inflammation in COVID-19 links focal microglial dysfunction with neuropathologies through IL-1/IL-6-related systemic inflammatory states

Fekete, R.; Simats, A.; Biro, E.; Cserep, C.; Schwarcz, A. D.; Posfai, B.; Szabadits, E.; Kornyei, Z.; Toth, K.; Kellermayer, A.; David, C.; Acsady, L.; Kontra, L.; Silvestre-Roig, C.; Moldvay, J.; Fillinger, J.; Hortobagyi, T.; Liesz, A.; Benko, S.; Denes, A.

10.1101/2023.06.23.546214 — immunology — Posted on 2023-06-23

1247 Germline-encoded specificities and the predictability of the B cell response

Vieira, M. C.; Palm, A.-K. E.; Stamper, C. T.; Tepora, M. E.; Nguyen, K. D.; Pham, T. D.; Boyd, S. D.; Wilson, P. C.; Cobey, S.

10.1101/2022.09.16.508315 — immunology — Posted on 2023-06-23

1248 Walking entrains unique oscillations in performance on a visual detection task

Davidson, M. J.; Verstraten, F.; Alais, D. J.

10.1101/2023.06.20.545691 — neuroscience — Posted on 2023-06-23

1249 Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B

Wu, Y.; Mumford, P.; Noy, S.; Cleverley, K.; Mrzyglod, A.; Luo, D.; Dalen, F. v.; Verdoes, M.; Fisher, E. M. C.; Wiseman, F. K.

10.1101/2023.06.20.545700 — neuroscience — Posted on 2023-06-23

1250 Chronic social stress blunts core body temperature and molecular rhythms of Rbm3 and Cirbp in mouse lateral habenula

Haniffa, S.; Narain, P.; Hughes, M.; Petkovic, A.; Susic, M.; Mlambo, V.; Chaudhury, D.

10.1101/2023.01.02.522528 — neuroscience — Posted on 2023-06-23

1251 Extended correlation functions for spatial analysis of multiplex imaging data

Bull, J. A.; Mulholland, E. J.; Leedham, S. J.; Byrne, H. M.

10.1101/2023.06.20.545678 — pathology — Posted on 2023-06-23

1252 Widespread gene regulator Psu inhibits transcription termination factor rho by forced hyper-oligomerization

Gjorgjevikj, D.; Kumar, N.; Wang, B.; Hilal, T.; Said, N.; Loll, B.; Artsimovitch, I.; Sen, R.; Wahl, M.

10.1101/2023.06.22.546067 — molecular biology — Posted on 2023-06-22

1253 Molecular pathway of mitochondrial preprotein import through the TOM-TIM23 supercomplex

Zhou, X.; Yang, Y.; Wang, G.; Wang, S.; Sun, D.; Ou, X.; Lian, Y.; Li, L.

10.1101/2023.06.21.546012 — molecular biology — Posted on 2023-06-23

1254 Absolute calibration of ribosome profiling assesses the dynamics of ribosomal flux on transcripts

Tomuro, K.; Mito, M.; Miyake, T.; Chow, S. Y. A.; Doi, M.; Ikeuchi, Y.; Shichino, Y.; Iwasaki, S.

10.1101/2023.06.20.545829 — molecular biology — Posted on 2023-06-23

1255 The receptor-like kinase BIR1 inhibits elicitor-induced plasmodesmata callose deposition and PTI gene expression and requires EDS1 and SOBIR1 to cause dose-dependent cell-death in Arabidopsis

GUZMAN-BENITO, I.; ROBINSON, C.; HUA, C.; SEDE, A. R.; ELVIRA-GONZALEZ, L.; PUNZON, I.; HEINLEIN, M.; NURNBERGER, T.; LLAVE, C.

10.1101/2023.06.23.546234 — plant biology — Posted on 2023-06-23

1256 Functional precision oncology for follicular lymphoma with patient-derived xenograft in avian embryos

Zala, M.; Lipinski, B.; Costechareyre, C.; Jarrosson, L.; Teinturier, R.; Julia, E.; Lacourrege, M.; Verney, A.; Guitton, J.; Glehen, A. T.; Bachy, E.; Salles, G.; Huet, S.; Genestier, L.; Castellani, V.; Bourgeois, C. D.; Sujobert, P.

10.1101/2023.06.22.546045 — cancer biology — Posted on 2023-06-22

1257 A Gene Therapy for Hereditary Nonpolyposis Colorectal Cancer using CRISPR-Cas9 Nickase

Kannan, S.; Man, J.

10.1101/2023.06.20.545835 — cancer biology — Posted on 2023-06-22

1258 p97/VCP targets Toxoplasma gondii vacuoles for parasite restriction in interferon-stimulated human cells

Clough, B.; Fisch, D.; Mize, T. H.; Encheva, V.; Snijders, A.; Frickel, E.

10.1101/2023.06.20.545566 — immunology — Posted on 2023-06-23

1259 Tomosyns attenuate SNARE assembly and synaptic depression by binding to VAMP2-containing template complexes

Meijer, M.; Ottl, M.; Yang, J.; Subkhangulova, A.; Kumar, A.; Groffen, A. J.; van Weering, J. R. T.; Zhang, Y.; Verhage, M.

10.1101/2023.06.20.545669 — neuroscience — Posted on 2023-06-23

1260 Multifaceted roles of rice ABA/stress-induced intrinsically disordered proteins in augmenting drought resistance

Lin, M.-C.; Tseng, I.-C.; Wang, C.-L.; Hsiao, W.-R.; Shih, Y.-J.; Lin, W.-D.; Yu, S.-M.; Ho, T.-h. D.

10.1101/2023.06.22.546131 — plant biology — Posted on 2023-06-23

1261 Photosynthetic acclimation mediates exponential growth of a desert plant in Death Valley summer

Prado, K.; Xue, B.; Johnson, J. E.; Field, S.; Stata, M.; Hawkins, C. L.; Hsia, R.-C.; Liu, H.; Cheng, S.; Rhee, S.

10.1101/2023.06.23.546155 — plant biology — Posted on 2023-06-23

1262 Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction

Latini, S.; Venafra, V.; Massacci, G.; Bica, V.; Graziosi, S.; Pugliese, G. M.; Iannuccelli, M.; Frioni, F.; Minnella, G.; Marra, J. D.; Chiusolo, P.; Pepe, G.; Helmer-Citterich, M.; Mougiakakos, D.; Boettcher, M.; Fischer, T.; Perfetto, L.; Sacco, F.

10.1101/2023.06.22.546072 — cancer biology — Posted on 2023-06-22

1263 Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

veith, i.; mencattini, a.; nurmik, m.; damei, i.; lansche, c.; brosseau, s.; gropplero, g.; corgnac, s.; filippi, j.; pote, n.; mordant, p.; tosello, j.; sedlik, c.; piaggio, e.; girard, n.; camonis, j.; shirvani, h.; mami-chouaib, f.; mechta-grigoriou, f.; descroix, s.; martinelli, e.; zalcman, g.; PARRINI, M. C.

10.1101/2023.06.21.545960 — cancer biology — Posted on 2023-06-22

1264 Developmental mitochondrial Complex I activity determines lifespan

Stefanatos, R.; Robertson, F.; Uribe, A. H.; Yu, Y.; Myers, K.; Castejon-Vega, B.; Kataura, T.; Martins, L. M.; Korolchuk, V. I.; Maddocks, O. D. K.; Sanz, A.

10.1101/2023.06.21.545894 — molecular biology — Posted on 2023-06-23

1265 The structure of the OmpA/Pal protein of Anaplasma phagocytophilum

Cadby, I. T.

10.1101/2023.06.15.545016 — microbiology — Posted on 2023-06-23

1266 Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors

Dhingra, S.; Chopade, P. M.; Vinnakota, R.; Kumar, J.

10.1101/2023.06.20.545708 — neuroscience — Posted on 2023-06-23

1267 Prothrombin Knockdown Protects Podocytes and Reduces Proteinuria in Glomerular Disease

Waller, A. P.; Wolfgang, K. J.; Abdelghani, E.; Stevenson, Z. S.; Muralidharan, K.; Wilkie, T. K.; Smoyer, W. E.; Nieman, M. T.; Kerlin, B. A.

10.1101/2023.06.20.544360 — physiology — Posted on 2023-06-23

1268 Utilizing a dual endogenous reporter system to identify functional regulators of aberrant stem cell and differentiation activity in colorectal cancer

Spisak, S.; Chen, D.; Likasitwatanakul, P.; Doan, P.; Li, Z.; Vizkeleti, L.; De Silva, P.; Giannakis, M.; Wolpin, B.; Qi, J.; Sethi, N.

10.1101/2023.06.21.545895 — cancer biology — Posted on 2023-06-22

1269 Quercetin Suppresses TNBC Cell by Targeting ORM2

Chen, Z.

10.1101/2023.06.20.545736 — cancer biology — Posted on 2023-06-22

1270 Integrated genomic and functional analyses of human skin-associated Staphylococcus reveals extensive inter- and intra-species diversity

Joglekar, P.; Conlan, S.; Lee-Lin, S.-Q.; Deming, C.; Kashaf, S. S.; Thomas, P.; Kong, H. H.; Segre, J.

10.1101/2023.06.22.546190 — microbiology — Posted on 2023-06-23

1271 Purinergic Preconditioning Induces Epigenomic and Transcriptomic Changes Resembling Epilepsy-associated Microglial States

Martins-Ferreira, R.; Calafell-Segura, J.; Chaves, J.; Ciudad, L.; Martins da Silva, A.; Pinho e Costa, P.; Leal, B.; Ballestar, E.

10.1101/2023.06.21.545837 — immunology — Posted on 2023-06-23

1272 A bone marrow ECM mimicking, animal-component free hydrogel identifies TNTs as key mediators of druggable cell-cell and cell-ECM crosstalk in an animal replacement organoid model.

Hockney, S.; Parker, J.; Tzivelekis, B.; Blair, H.; Dalgarno, K.; Pal, D.

10.1101/2023.06.20.545732 — cancer biology — Posted on 2023-06-22

1273 Missense mutations in the calcium-activated chloride channel TMEM16A promote tumor growth by activating oncogenic signaling in Human Cancer.

Cruz-Rangel, S.; De Jesus-Perez, J. J.; Gopalkrishnan, A.; Gomez-Casal, R.; Pacheco, J.; Brown, M. R.; Yassin-Kassab, A.; Hammond, G. R.; Bertrand, C. A.; Arreola, J.; Kiselyov, K.; Umamaheswar, D.

10.1101/2023.06.21.545912 — cancer biology — Posted on 2023-06-22

1274 ArcheD, a residual neural network for prediction of cerebrospinal fluid amyloid-beta from amyloid PET images

Tagmazian, A. A.; Schwarz, C.; Lange, C.; Pitkanen, E.; Vuoksimaa, E.

10.1101/2023.06.20.545686 — neuroscience — Posted on 2023-06-23

1275 Mesoscale simulations predict the role of synergistic cerebellar plasticity during classical eyeblink conditioning

Geminiani, A.; Casellato, C.; Boele, H.-J.; Pedrocchi, A.; De Zeeuw, C.; D'Angelo, E.

10.1101/2023.06.20.545667 — neuroscience — Posted on 2023-06-23

1276 Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations.

Jimenez, L.; Barman, B.; Jung, Y. J.; Cocozza, L. N.; Krystofiak, E.; Saffold, C. E.; Vickers, K. C.; Wilson, J. T.; Dawson, T. R.; Weaver, A. M.

10.1101/2023.06.21.545797 — cancer biology — Posted on 2023-06-22

1277 Tradeoffs in Modeling Context Dependency in Complex Trait Genetics

Weine, E.; Smith, S. P.; Knowlton, R. K.; Harpak, A.

10.1101/2023.06.21.545998 — genomics — Posted on 2023-06-23

1278 Accounting for statistical non-additive interactions enables the recovery of missing heritability from GWAS summary statistics

Smith, S. P.; Darnell, G.; Udwin, D.; Harpak, A.; Ramachandran, S.; Crawford, L.

10.1101/2022.07.21.501001 — genomics — Posted on 2023-06-23

1279 Genetic characterization of a captive marmoset colony using genotype-by-sequencing

Cole, S. A.; Lyke, M. M.; Christensen, C.; Newman, D.; Bagwell, A.; Galindo, S.; Glenn, J.; Layne-Colon, D.; Sayers, K.; Tardif, S. D.; Cox, L. A.; Ross, C. N.; Cheeseman, I. H.

10.1101/2023.06.22.545969 — genetics — Posted on 2023-06-23

1280 Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill Required for Fertilization

Jablonski, M.; Luque, G. M.; Gomez-Elias, M.; Sanchez-Cardenas, C.; Xu, X.; de la Vega-Beltran, J. L.; Corkidi, G.; Linares, A.; Abonza, V.; Krapf, D.; Krapf, D.; Darszon, A.; Guerrero, A.; Buffone, M. G.

10.1101/2023.06.22.546073 — cell biology — Posted on 2023-06-23

1281 Visual periodicity reveals distinct attentional signatures for face and non-face categories

Quek, G. L.; de Heering, A.

10.1101/2023.06.22.546207 — neuroscience — Posted on 2023-06-23

1282 Longitudinal associations between language network characteristics in the infant brain and school-age reading abilities are mediated by early-developing phonological skills

Tang, X.; Turesky, T. K.; Escalante, E. S.; Loh, M. Y.; Xia, M.; Yu, X.; Gaab, N.

10.1101/2023.06.22.546194 — neuroscience — Posted on 2023-06-23

1283 Overcoming migratory exhaustion: Expression of Matrix metalloproteinase-8 (MMP-8) promotes tumor infiltration and anti-tumor activity of CAR-T cells

Bandey, I. N.; Montalvo, M. J.; Singh, H.; Varadarajan, N.

10.1101/2023.06.21.545815 — cancer biology — Posted on 2023-06-22

1284 Deep learning, data ramping, and uncertainty estimation for detecting artifacts in large, imbalanced databases of MRI images

Pizarro, R.; Assemlal, H.-E.; Boopathy Jegathambal, S. K.; Jubaulte, T.; Antel, S.; Arnold, D.; Shmuel, A.

10.1101/2023.06.20.545422 — bioinformatics — Posted on 2023-06-23

1285 circRNA-sponging: a pipeline for extensive analysis of circRNA expression and their role in miRNA sponging

Hoffmann, M.; Schwartz, L.; Ciora, O.-A.; Trummer, N.; Willruth, L.-L.; Jankowski, J.; Lee, H. K.; Baumbach, J.; Furth, P. A.; Hennighausen, L.; List, M.

10.1101/2023.01.19.524495 — bioinformatics — Posted on 2023-06-23

1286 BiGPICC: a graph-based approach to identifying carcinogenic gene combinations from mutation data

Oles, V.; Dash, S.; Anandakrishnan, R.

10.1101/2023.02.06.527327 — bioinformatics — Posted on 2023-06-23

1287 Metagenomics for pathogen detection during a wildlife mortality event in songbirds

Mwakibete, L.; Greening, S. S.; Kalantar, K.; Ahyong, V.; Anis, E.; Miller, E. A.; Needle, D. B.; Oglesbee, M.; Thomas, W. K.; Sevigny, J. L.; Gordon, L. M.; Nemeth, N. M.; Ogbunugafor, C. B.; Ayala, A. J.; Faith, S. A.; Neff, N.; Detweiler, A. M.; Baillargeon, T.; Tanguay, S.; Simpson, S. D.; Murphy, L. A.; Ellis, J. C.; Tato, C. M.; Gagne, R. B.

10.1101/2023.06.20.545358 — genomics — Posted on 2023-06-23

1288 CLOCI: Unveiling cryptic gene clusters with generalized detection

Konkel, Z.; Kubatko, L.; Slot, J.

10.1101/2023.06.20.545441 — genomics — Posted on 2023-06-23

1289 Parasites make hosts more profitable but less available to predators

Prosnier, L.; Loeuille, N.; Hulot, F. D.; Renault, D.; Piscart, C.; Bicocchi, B.; Deparis, M.; Lam, M.; Medoc, V.

10.1101/2022.02.08.479552 — ecology — Posted on 2023-06-23

1290 Endosymbiont diversity across native and invasive brown widow spider populations

Mowery, M. A.; Rosenwald, L.; Chapman, E.; Lubin, Y.; Segoli, M.; Khoza, T.; Lyle, R.; White, J.

10.1101/2023.06.22.546064 — microbiology — Posted on 2023-06-22

1291 Phantom oscillations in principal component analysis

Shinn, M.

10.1101/2023.06.20.545619 — neuroscience — Posted on 2023-06-23

1292 Clarifying the Transcriptional Profiles of Malignant Clones through Multiscale and Multiomic Analysis of Individual Tumors

Schupp, P. G.; Shelton, S. J.; Brody, D. J.; Eliscu, R.; Johnson, B. E.; Mazor, T.; Kelley, K. W.; Potts, M. B.; McDermott, M. W.; Huang, E. J.; Lim, D. A.; Pieper, R. O.; Berger, M. S.; Costello, J. F.; Phillips, J. J.; Oldham, M. C.

10.1101/2023.06.21.545365 — cancer biology — Posted on 2023-06-22

1293 Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice

Barravecchia, I.; Lee, J. M.; Manassa, J.; Magnuson, B.; Cavanaugh, S.; Steele, N. G.; Espinoza, C.; Galban, C. J.; Ramnath, N.; Frankel, T. L.; Pasca di Magliano, M.; Galban, S.

10.1101/2023.06.20.545616 — cancer biology — Posted on 2023-06-22

1294 Single nucleotide variation catalogue from clinical isolates mapped on tertiary and quaternary structures of ESX-1 related proteins reveals critical regions as putative Mtb therapeutic targets

Tzfadia, O.; Siroy, A.; Vujkovic, A.; Snobre, J.; Vargas, R.; Gijsbers, A.; Mulders, W.; Meehan, C.; Farhat, M. R.; Peters, P. J.; de Jong, B. C.; Ravelli, R.

10.1101/2023.06.22.507254 — genomics — Posted on 2023-06-23

1295 A Risk-reward Examination of Sample Multiplexing Reagents for Single Cell RNA-Seq

Brown, D. V.; Anttila, C. J. A.; Ling, L.; Grave, P.; Baldwin, T. M.; Munnings, R.; Farchione, A. J.; Bryant, V. L.; Dunstone, A.; Biben, C.; Taoudi, S.; Weber, T. S.; Naik, S. H.; Hadla, A.; Barker, H. E.; Vandenberg, C. J.; Dall, G.; Scott, C. L.; Moore, Z.; Whittle, J. R.; Freytag, S.; Best, S. A.; Papenfuss, A. T.; Olechnowicz, S. W. Z.; MacRaild, S. E.; Wilcox, S.; Hickey, P. F.; Amann-Zalcenstein, D.; Bowden, R.

10.1101/2023.06.20.544880 — genomics — Posted on 2023-06-23

1296 Interpreting structure in sequence count data with differential expression analysis allowing for grades of membership

Carbonetto, P.; Luo, K.; Sarkar, A.; Hung, A.; Tayeb, K.; Pott, S.; Stephens, M.

10.1101/2023.03.03.531029 — genomics — Posted on 2023-06-23

1297 MX2 restricts HIV-1 and herpes simplex virus-1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

Moschonas, G. D.; Delhaye, L.; Cooreman, R.; Bath, A.; De Sutter, D.; Parthoens, E.; Desmet, A.-S.; Maciejczuk, A.; Grzesik, H.; Lippens, S.; Debyser, Z.; Eyckerman, S.; Saelens, X.

10.1101/2023.06.22.545931 — microbiology — Posted on 2023-06-22

1298 A novel RofA-family transcriptional regulator, GadR, controls the development of acid resistance in Listeria monocytogenes.

Wu, J.; McAuliffe, O.; O'Byrne, C. P.

10.1101/2023.06.22.546042 — microbiology — Posted on 2023-06-22

1299 Epigenomic analysis of Formalin-Fixed Paraffin-Embedded samples by CUT&Tag

Henikoff, S.; Henikoff, J. G.; Ahmad, K.; Paranal, R. M.; Janssens, D. H.; Russell, Z. R.; Szulzewsky, F.; Kugel, S.; Holland, E. C.

10.1101/2023.06.20.545743 — cancer biology — Posted on 2023-06-22

1300 Phylogenetic and population structure of the nod-free but nodulating Bradyrhizobium phylogroup

Ling, L.; Camuel, A.; Wang, S.; Wang, X.; Lin, X.; Nouwen, N.; Giraud, E.; Luo, H.

10.1101/2023.06.14.544914 — genomics — Posted on 2023-06-23

1301 Identification of a new human polyomavirus in distinct populations and tissues

Torres, C.; Correa, R. M.; Picconi, M. A.; Buck, C. B.; Mbayed, V. A.

10.1101/2023.06.22.545219 — microbiology — Posted on 2023-06-22

1302 The mechanism for polar localization of the type IVa pilus machine

Herfurth, M.; Perez-Burgos, M.; Sogaard-Andersen, L.

10.1101/2023.06.22.546063 — microbiology — Posted on 2023-06-22

1303 Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment

Rowdo, F. P. M.; Xiao, G.; Khramtsova, G. F.; Nguyen, J.; Olopade, O.; Martini, R.; Stonaker, B.; Boateng, R.; Oppong, J. K.; Adjei, E. K.; Awuah, B.; Kyei, I.; Aitpillah, F. S.; Adinku, M. O.; Ankomah, K.; Osei-Bonsu, E. B.; Gyan, K. K.; Altorki, N. K.; Cheng, E.; Ginter, P. S.; Hoda, S.; Newman, L.; Elemento, O.; Davis, M. B.; Martin, M. L.; Bargonetti, J.

10.1101/2023.06.22.544406 — cancer biology — Posted on 2023-06-22

1304 Architecture of the Vertebrate Egg Coat and Structural Basis of the ZP2 Block to Polyspermy

Nishio, S.; Emori, C.; Wiseman, B.; Fahrenkamp, D.; Dioguardi, E.; Zamora-Caballero, S.; Bokhove, M.; Han, L.; Stsiapanava, A.; Lu, Y.; Kodani, M.; Bainbridge, R. E.; Komondor, K. M.; Carlson, A. E.; Landreh, M.; de Sanctis, D.; Yasumasu, S.; Ikawa, M.; Jovine, L.

10.1101/2023.06.21.544075 — biophysics — Posted on 2023-06-22

1305 Enrichment of hard sweeps on the X chromosome compared to autosomes in six Drosophila species

Harris, M.; Kim, B. Y.; Garud, N. R.

10.1101/2023.06.21.545888 — evolutionary biology — Posted on 2023-06-23

1306 Major patterns in the introgression history of Heliconius butterflies

Thawornwattana, Y.; Seixas, F. A.; Yang, Z.; Mallet, J.

10.1101/2023.06.21.545923 — evolutionary biology — Posted on 2023-06-23

1307 TRAF6 initiates inflammatory signaling via organizing membraneless cytoplasmic condensates

Yin, H. H.; Wang, J.; Zhong, X.

10.1101/2023.06.19.545655 — immunology — Posted on 2023-06-23

1308 Data-driven biomarkers outperform theory-based biomarkers in predicting stroke motor outcomes

Olafson, E.; Sperber, C.; Jamison, K. W.; Bowren, M. D.; Boes, A. D.; Andrushko, J. W.; Borich, M. R.; Boyd, L. A.; Cassidy, J. M.; Conforto, A. B.; Cramer, S. C.; Dula, A. N.; Geranmayeh, F.; Hordacre, B.; Jahanshad, N.; Kautz, S. A.; Lo, B.; Macintosh, B. J.; Piras, F.; Robinson, A. D.; Seo, N. J.; Soekadar, S. R.; Thomopoulos, S. I.; Vecchio, D.; Weng, T. B.; Westlye, L. T.; Winstein, C. J.; Wittenberg, G. F.; Wong, K. A.; Thompson, P. M.; Liew, S.-L.; Kuceyeski, A. F.

10.1101/2023.06.19.545638 — neuroscience — Posted on 2023-06-23

1309 ParSe 2.0: A web application that enables proteome-scale searches for sequences that drive protein-mediated phase separation

Wilson, C.; Lewis, K. A.; Fitzkee, N. C.; Hough, L. E.; Whitten, S. T.

10.1101/2023.06.20.545714 — biophysics — Posted on 2023-06-22

1310 In-situ spectroscopic detection of large-scale reorientations of transmembrane α-helices during viroporin channel opening

Paschke, R. R.; Mohr, S.; Lange, S.; Lange, A.; Kozuch, J.

10.1101/2023.06.22.546036 — biophysics — Posted on 2023-06-22

1311 scDeepInsight: a supervised cell-type identification method for scRNA-seq data with deep learning

JIA, S.; Lysenko, A.; Boroevich, K.; Sharma, A.; Tsunoda, T.

10.1101/2023.03.09.531861 — bioinformatics — Posted on 2023-06-23

1312 Visualization of hemoglobin oxygen saturation distribution in small animals: an in vivo application of a 3D photoacoustic imaging scanner with a hemispherical detector array

Asao, Y.; Hirano, R.; Nagae, K.; Sekiguchi, H.; Aiso, S.; Watanabe, S.; Sato, M.; Yagi, T.; Kondoh, S. K.

10.1101/2023.06.19.545650 — bioengineering — Posted on 2023-06-23

1313 Toward transparent taxonomy: an interactive web-tool for evaluating competing taxonomic arrangements

Vernygora, O. V.; Sperling, F. A. H.; Dupuis, J. R.

10.1101/2023.06.20.545819 — evolutionary biology — Posted on 2023-06-23

1314 Positive selection and relaxed purifying selection contribute to rapid evolution of male-biased genes in a dioecious flowering plant

Zhao, L.; Zhou, W.; He, J.; Li, D.-Z.; Li, H.-T.

10.1101/2023.06.21.545900 — evolutionary biology — Posted on 2023-06-23

1315 TRAILS: tree reconstruction of ancestry using incomplete lineage sorting

Rivas-Gonzalez, I.; Schierup, M. H.; Wakeley, J.; Hobolth, A.

10.1101/2023.06.22.546039 — evolutionary biology — Posted on 2023-06-23

1316 Cell-based assay to determine Type 3 Secretion System translocon assembly in Pseudomonas aeruginosa using split luciferase

Guo, H.; Geddes, E. J.; Opperman, T. J.; Heuck, A. P.

10.1101/2023.06.22.546099 — microbiology — Posted on 2023-06-22

1317 Cryptic bacterial pathogens of diatoms peak during senescence of a winter diatom bloom

Branscombe, L.; Harrison, E. L.; Zhi Yi, C.; Keys, M.; Widdicombe, C.; Wilson, W. H.; Cunliffe, M.; Helliwell, K. E.

10.1101/2023.06.22.545670 — microbiology — Posted on 2023-06-22

1318 Maturational networks of fetal brain activity reveal emerging connectivity patterns prior to ex-utero exposure

Karolis, V. R.; Fitzgibbon, S. P.; Cordero-Grande, L.; Farahibozorg, S.-R.; Price, A. N.; Hughes, E. J.; Fetit, A. E.; Kyriakopoulou, V.; Pietsch, M.; Rutherford, M.; Rueckert, D.; Hajnal, J. V.; Edwards, A. D.; O'Muircheartaigh, J.; Duff, E.; Arichi, T.

10.1101/2022.06.14.495883 — neuroscience — Posted on 2023-06-23

1319 Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

Gui, Y.; Kim, Y.; Brenna, S.; Wilmes, M.; Zaghen, G.; Kuchenbecker-Poels, L.; Voss, H. L.; Gocke, A.; Schlueter, H.; Schweizer, M.; Altmeppen, H. C.; Magnus, T.; Levy, E.; Puig, B.

10.1101/2023.06.16.545303 — neuroscience — Posted on 2023-06-23

1320 Temporal scaling of dopamine neuron firing and dopamine release by distinct ion channels shape behavior

Juarez, B.; Kong, M.-S.; Jo, Y. S.; Elum, J. E.; Yee, J. X.; Ng-Evans, S.; Cline, M.; Hunker, A. C.; Quinlan, M. A.; Baird, M. A.; Elerding, A. J.; Johnson, M.; Ban, D.; Mendez, A.; Goodwin, N.; Soden, M. E.; Zweifel, L.

10.1101/2021.08.27.457972 — neuroscience — Posted on 2023-06-23

1321 Delineating Structural Propensities of the 4E-BP2 Protein via Integrative Modelling and Clustering

Tsangaris, T. E.; Smyth, S.; Gomes, G.-N. W.; Liu, Z. H.; Milchberg, M.; Wasney, G. A.; Bah, A.; Forman-Kay, J. D.; Gradinaru, C. C.

10.1101/2023.06.20.545775 — biophysics — Posted on 2023-06-22

1322 Uncovering the association mechanism between two intrinsically flexible proteins

Davalos, A. L.; Rivera, J. D.; Favaro, D. C.; Oliveira, R. J. d.; Carretero, G.; Lacerda, C. D.; Cuccovia, I. M.; Cardoso, M. V. C.; Farah, C. S.; Salinas, R. K.

10.1101/2023.06.19.545625 — biophysics — Posted on 2023-06-22

1323 Dawnn: single-cell differential abundance with neural networks

Hall, G. T.; Castellano, S.

10.1101/2023.05.05.539427 — bioinformatics — Posted on 2023-06-23

1324 AlphaFold2 can predict single-mutation effects on structure and phenotype

Mcbride, J. M.; Reinharz, V.; Polev, K.; Grzybowski, B. A.; Tlusty, T.

10.1101/2022.04.14.488301 — biochemistry — Posted on 2023-06-23

1325 How well do rudimentary plasticity rules predict adult visual object learning?

Lee, M. J.; DiCarlo, J. J.

10.1101/2022.12.31.522402 — animal behavior and cognition — Posted on 2023-06-23

1326 Spatial and temporal distribution of ribosomes in single cells reveals aging differences between old and new daughters of Escherichia coli

Chao, L.; Chen, C. K.; Shi, C.; Rang, C. U.

10.1101/2023.06.21.545935 — evolutionary biology — Posted on 2023-06-23

1327 Sperm production and allocation respond to perceived risk of sperm competition in the black soldier fly Hermetia illucens

Manas, F.; Labrousse, C.; Bressac, C.

10.1101/2023.06.20.544772 — evolutionary biology — Posted on 2023-06-23

1328 Relationship between prokaryotic GC content and environmental salinity

Hu, E.-Z.; Sun, S.; Niu, D.-K.

10.1101/2023.05.07.539728 — evolutionary biology — Posted on 2023-06-23

1329 Structural and functional analysis of vaccinia viral fusion complex component protein A28 through NMR and molecular dynamic simulations

Kao, C.-F.; Tsai, M.-H.; Carillo, K. J.; Tzou, D.-L.; Chang, W.

10.1101/2023.06.22.546044 — microbiology — Posted on 2023-06-22

1330 Paeniclostridium sordellii NanS works synergistically with TcsL to increase cytotoxicity and the severity of pathogenesis in the murine uterus

Bernard, S. C.; Kroh, H.; Washington, M. K.; Lacy, D. B.

10.1101/2023.06.22.546043 — microbiology — Posted on 2023-06-22

1331 Objects in familiar constellations evoke high-level representations of real-world size

Quek, G. L.; Theodorou, A.; Peelen, M. V.

10.1101/2023.05.30.542965 — neuroscience — Posted on 2023-06-23

1332 Storm: Incorporating transient dynamics to infer the RNA velocity with metabolic labeling information

Peng, Q.; Qiu, X.; Li, T.

10.1101/2023.06.21.545990 — systems biology — Posted on 2023-06-23

1333 Tiny Earth CURE improves student persistence in science

Miller, S.; Aldana, C. C.; Du, W.; Lee, H.; Maldonado, N.; Sandoval, P.; Vong, J.; Young, G.; Handelsman, J.; Broderick, N. A.; Hernandez, P. R.; Estrada, M.

10.1101/2023.06.21.543782 — scientific communication and education — Posted on 2023-06-23

1334 Intrinsically disordered regions in the transcription factor MYC:MAX provide DNA selectivity via intramolecular interactions

Schuetz, S.; Bergsdorf, C.; Haenni-Holzinger, S.; Lingel, A.; Renatus, M.; Gossert, A. D.; Jahnke, W.

10.1101/2023.06.21.545551 — biophysics — Posted on 2023-06-22

1335 GeNNius: An ultrafast drug-target interaction inference method based on graph neural networks

Veleiro, U.; de la Fuente, J.; Serrano, G.; Pizurica, M.; Casals, M.; Pineda-Lucena, A.; Vicent, S.; Ochoa, I.; Gevaert, O.; Hernaez, M.

10.1101/2023.06.20.545544 — bioinformatics — Posted on 2023-06-23

1336 Decellularisation and characterisation of porcine pleura for lung tissue engineering

Vikranth, T.; Dale, T. P.; Forsyth, N. R.

10.1101/2023.06.20.545830 — bioengineering — Posted on 2023-06-23

1337 Putting a new spin on insect jumping performance using 3D modeling and computer simulations of spotted lanternfly nymphs

Li, C.; Xu, A.; Beery, E. M.; Hsieh, S. T.; Kane, S. A.

10.1101/2023.06.20.545794 — animal behavior and cognition — Posted on 2023-06-23

1338 Improved characterization of soil organic matter by integrating FTICR-MS, liquid chromatography tandem mass spectrometry and molecular networking: a case study of root litter decay under drought conditions

DiDonato, N.; Rivas-Ubach, A.; Kew, W.; Clendinen, C.; Sokol, N.; Kyle, J. E.; Martinez, C. E.; Foley, M. M.; Tolic, N.; Pett-Ridge, J.; Pasa-Tolic, L.

10.1101/2023.06.20.545455 — ecology — Posted on 2023-06-23

1339 Assembly archetypes in ecological communities

Flores-Arguedas, H.; Antolin-Camarena, O.; Saavedra, S.; Angulo, M. T.

10.1101/2023.06.20.545780 — ecology — Posted on 2023-06-23

1340 Uncovering novel endolysins against methicillin-resistant Staphylococcus aureus using microbial single-cell genome sequencing

Yoda, T.; Matsuhashi, A.; Matsushita, A.; Shibagaki, S.; Sasakura, Y.; Aoki, K.; Hosokawa, M.; Tsuda, S.

10.1101/2023.06.22.546026 — microbiology — Posted on 2023-06-22

1341 SRC family kinase inhibition rescues molecular and behavioral phenotypes, but not protein interaction network dynamics, in a mouse model of Fragile X syndrome

Stamenkovic, V.; Lautz, J. D.; Harsh, F. M.; Smith, S. E. P.

10.1101/2023.06.20.545800 — neuroscience — Posted on 2023-06-23

1342 Accommodation and wavelength: the effect of longitudinal chromatic aberration on the stimulus-response curve.

Fernandez-Alonso, M.; Finch, A.; Love, G. D.; Read, J. C. A.

10.1101/2023.06.20.545755 — physiology — Posted on 2023-06-23

1343 Critical thermal maxima and oxygen uptake in Elysia viridis (Montagu, 1804), a sea slug capable of photosynthesis

Laetz, E. M. J.; Kahyaoglu, C.; Borgstein, N. M.; Merkx, M.; van der Meij, S.; Verberk, W.

10.1101/2023.06.19.545621 — physiology — Posted on 2023-06-23

1344 Revisiting annotation of Schistosoma mansoni Micro-Exon Gene (MEG) family

Nedvedova, S.; De Stefano, D.; Walker, O.; Hologne, M.; Miele, A. E.

10.1101/2023.06.21.545858 — bioinformatics — Posted on 2023-06-23

1345 Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity

Wang, M.; Patsenker, J.; Li, H.; Kluger, Y.; Kleinstein, S.

10.1101/2023.06.21.545145 — bioinformatics — Posted on 2023-06-23

1346 Direct quantification of sinking velocities across unicellular algae

Miettinen, T. P.; Gomez, A. L.; Wu, Y.; Wu, W.; Usherwood, T. R.; Roller, B. R. K.; Polz, M. F.; Manalis, S. R.

10.1101/2023.06.20.545838 — ecology — Posted on 2023-06-23

1347 SRSF1-mediated alternative splicing of Tial1/Tiar is essential for homing and self-renewal in mouse spermatogonial stem cells

Sun, L.; Lv, Z.; Chen, X.; Ye, R.; Tian, S.; Wang, C.; Xie, X.; Yan, L.; Yao, X.; Shao, Y.; Cui, S.; Chen, J.; Liu, J.

10.1101/2023.06.21.545885 — developmental biology — Posted on 2023-06-23

1348 Exposure to the aryl hydrocarbon receptor agonist dioxin disrupts formation of the muscle, nerves, and vasculature in the developing jaw

Cintron-Rivera, L. G.; Burns, N.; Patel, R.; Plavicki, J.

10.1101/2023.06.22.546117 — developmental biology — Posted on 2023-06-23

1349 Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury

DiGiovanni, G. T.; Han, W.; Sherrill, T.; Taylor, C. J.; Nichols, D. S.; Geis, N. M.; Singha, U. K.; Calvi, C. L.; McCall, A. S.; Dixon, M. M.; Lui, Y.; Jang, J.-H.; Gutor, S. S.; Polosukhin, V. V.; Blackwell, T. S.; Kropski, J. A.; Gokey, J. J.

10.1101/2023.06.22.545997 — cell biology — Posted on 2023-06-23

1350 GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis

10.1101/2023.06.20.542249 — immunology — Posted on 2023-06-23

1351 A Machine Learning Approach for Real-time Cortical State Estimation

Weiss, D. A.; Borsa, A. M.; Pala, A.; Sederberg, A. J.; Stanley, G. B.

10.1101/2023.06.20.545785 — neuroscience — Posted on 2023-06-23

1352 Identification of Natural Antiviral Drug Candidates Against Tilapia Lake Virus: Computational Drug Design Approaches

Brown, C. L.; Sumon, M. A. A.; Asseri, A. H.; Molla, M. H. R.; Aljahdali, M. O.; Hasan, M. R.; Rahman, M. A.; Hasan, M. T.; Sumon, T. A.; Gabr, M. H.; Islam, M. S.; Fakhurji, B.; Moulay, M.; Larson, E.

10.1101/2023.06.19.545628 — pharmacology and toxicology — Posted on 2023-06-23

1353 Mapping MAVE data for use in human genomics applications

Arbesfeld, J. A.; Da, E. Y.; Kuzma, K.; Paul, A.; Farris, T.; Riehle, K.; Agostinho, N. D. S.; Safer, J. F.; Milosavljevic, A.; Foreman, J.; Firth, H. V.; Hunt, S. E.; Iqbal, S.; Cline, M.; Rubin, A. F.; Wagner, A. H.

10.1101/2023.06.20.545702 — bioinformatics — Posted on 2023-06-23

1354 SMART: reference-free deconvolution for spatial transcriptomics using marker-gene-assisted topic models

Yang, C. X.; Sin, D. D.; Ng, R. T.

10.1101/2023.06.20.545793 — bioinformatics — Posted on 2023-06-23

1355 Spatiotemporal Control of Genomics and Epigenomics by Ultrasound

Wu, Y.; Huang, Z.; Liu, Y.; Yoon, C.-W.; Sun, K.; Situ, Y.; Ho, P.; Yuan, Z.; Zhu, L.; Eyquem, J.; Zhao, Y.; Liu, T.; Kwong, G. A.; Chien, S.; Wang, Y.

10.1101/2023.06.21.544125 — bioengineering — Posted on 2023-06-23

1356 Protein evolvability under rewired genetic codes

Rozhonova, H.; Marti-Gomez, C.; McCandlish, D. M.; Payne, J. L.

10.1101/2023.06.20.545706 — evolutionary biology — Posted on 2023-06-23

1357 Can higher-order interactions resolve the species coexistence paradox?

Gibbs, T. L.; Gellner, G.; Levin, S. A.; McCann, K. S.; Hastings, A.; Levine, J. M.

10.1101/2023.06.19.545649 — ecology — Posted on 2023-06-23

1358 The Role of Sympathetic Innervation in Neonatal Muscle Growth and Neuromuscular Contractures

Runkel, M. T.; Tarabishi, A.; Shay-Winkler, K.; Emmert, M. E.; Goh, Q.; Cornwall, R.

10.1101/2023.06.20.545748 — developmental biology — Posted on 2023-06-22

1359 polo affects cell fate upon ionizing radiation in Drosophila hematopoietic progenitors by negatively regulating lok

Nguyen, T. T. N.; Shim, J.; Chen, G.-C.; Song, Y.-H.

10.1101/2023.06.22.546047 — developmental biology — Posted on 2023-06-22

1360 Deciphering the genetic interactions between Pou4f3, Gfi1 and Rbm24 in maintaining cochlear hair cell survival

Wang, G.; Gu, Y.; Liu, Z.

10.1101/2023.06.22.546097 — developmental biology — Posted on 2023-06-22

1361 Transcriptomic profiling of murine GnRH neurons reveals developmental trajectories linked to human reproduction

Zouaghi, Y.; Alpern, D.; Gardeux, V.; Russeil, J.; Deplancke, B.; Santoni, F.; Pitteloud, N.; Messina, A.

10.1101/2023.06.22.546062 — developmental biology — Posted on 2023-06-23

1362 Model-free Identification of Phenotype-Relevant Variables From Dose Response Data

Veliz-Cuba, A.; Murrugarra, D.; Voss, R.

10.1101/2023.06.21.545943 — developmental biology — Posted on 2023-06-23

1363 Multimodule imaging of the hierarchical equine hoof wall porosity and structure

Jasiuk, I.; Mahrous, M. A.; Chadha, C.; Robins, P. L.; Bonney, C.; Boateng, K. A.; Meyers, M.

10.1101/2023.06.21.545722 — developmental biology — Posted on 2023-06-23

1364 Purine nucleotide limitation undermines antibiotic action in clinical Escherichia coli

Lubrano, P.; Schramm, T.; Lorenz, E.; Alvarado, A.; Eigenmann, S. C.; Stadelmann, A.; Thavapalan, S.; Waffenschmidt, N.; Glatter, T.; Peter, S.; Drescher, K.; Link, H.

10.1101/2023.06.22.546106 — microbiology — Posted on 2023-06-22

1365 Hippocampal Codes for Real-World Human Navigation

Graves, K. N.; Letrou, A.; Gray, T. E.; Quraishi, I. H.; Turk-Browne, N. B.

10.1101/2023.06.22.545396 — neuroscience — Posted on 2023-06-22

1366 IFT cargo and motors associate sequentially with IFT trains to enter cilia

Mitra, A.; Loseva, E.; Peterman, E. J. G.

10.1101/2023.06.20.545804 — biophysics — Posted on 2023-06-22

1367 Nonequilibrium switching of segmental states can influence compaction of chromatin

Sahoo, S.; Kadam, S.; Padinhateeri, R.; Kumar, P. B. S.

10.1101/2023.06.21.546028 — biophysics — Posted on 2023-06-22

1368 Genome-wide kinetic profiling of pre-mRNA 3' end cleavage

Torres-Ulloa, L.; Calvo-Roitberg, E.; Pai, A. A.

10.1101/2023.06.21.545926 — genomics — Posted on 2023-06-22

1369 TRAILS: tree reconstruction of ancestry using incomplete lineage sorting

Rivas-Gonzalez, I.; Schierup, M. H.; Wakeley, J.; Hobolth, A.

10.1101/2023.06.22.546039 — evolutionary biology — Posted on 2023-06-22

1370 Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse

Schifferl, D.; Scholze-Wittler, M.; Villaronga Luque, A.; Pustet, M.; Wittler, L.; Veenvliet, J. V.; Koch, F.; Herrmann, B. G.

10.1101/2023.06.21.545916 — developmental biology — Posted on 2023-06-22

1371 Pax3 and Pax7 function in combination with Mitf to generate melanophores and xanthophores in medaka and zebrafish

Miyadai, M.; Takada, H.; Shiraishi, A.; Kimura, T.; Watakabe, I.; Kobayashi, H.; Nagao, Y.; Naruse, K.; Higashijima, S.-i.; Shimizu, T.; Kelsh, R.; Hibi, M.; Hashimoto, H.

10.1101/2023.06.22.546052 — developmental biology — Posted on 2023-06-22

1372 A genetic program for vascular pericyte precursors

Childs, S. J.; Ahuja, S.; Adjekukor, C.; Li, Q.; Kocha, K. M.; Rosin, N.; Labit, E.; Sinha, S.; Narang, A.; Long, Q.; Biernaskie, J.; Huang, P.

10.1101/2023.06.21.545941 — developmental biology — Posted on 2023-06-22

1373 Zona incerta distributes a broad movement signal that modulates behavior

Hormigo, S.; Zhou, J.; Chabbert, D.; sajid, M.; Busel, N.; Castro-Alamancos, M. A.

10.1101/2023.06.21.545874 — neuroscience — Posted on 2023-06-22

1374 In-vivo whole-cortex estimation of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youth

Zhang, S.; Larsen, B.; Sydnor, V. J.; Zeng, T.; An, L.; Yan, X.; Kong, R.; Kong, X.; Gur, R. C.; Gur, R. E.; Moore, T. M.; Wolf, D. H.; Holmes, A. J.; Xie, Y.; Zhou, J. H.; Fortier, M. V.; Tan, A. P.; Gluckman, P.; Chong, Y. S.; Meaney, M.; Deco, G.; Satterthwaite, T. D.; Yeo, B. T. T.

10.1101/2023.06.22.546023 — neuroscience — Posted on 2023-06-22

1375 C9orf72 polyPR directly binds to various nuclear transport components

Jafarinia, H.; Van der Giessen, E.; Onck, P.

10.1101/2023.06.22.546068 — biophysics — Posted on 2023-06-22

1376 UVA hyperspectral light-sheet microscopy for volumetric metabolic imaging: application to pre-implantation embryo development

Morizet, J.; Chow, D.; Wijesinghe, P.; Schartner, E.; Dwapanyin, G. O.; Dubost, N.; Bruce, G. D.; Anckaert, E.; Dunning, K.; Dholakia, K.

10.1101/2023.06.21.545939 — biophysics — Posted on 2023-06-22

1377 Opportunistic bacteria of grapevine crown galls are equipped with the genomic repertoire for opine utilization

Faist, H.; Ankenbrand, M. J.; Sickel, W.; Hentschel, U.; Keller, A.; Deeken, R.

10.1101/2023.06.20.545721 — genomics — Posted on 2023-06-22

1378 Chance favors the prepared genomes: horizontal transfer shapes the emergence of antibiotic resistance mutations in core genes.

Coluzzi, C.; Guillemet, M.; Mazzamurro, F.; Touchon, M.; Godfroid, M.; Achaz, G.; Glaser, P.; Rocha, E. P. C.

10.1101/2023.06.20.545734 — evolutionary biology — Posted on 2023-06-22

1379 Rats synchronize predictively to metronomes

Rajendran, V. G.; Tsdaka, Y.; Keung, T. Y.; Schnupp, J. W. H.; Nelken, I.

10.1101/2023.06.19.545615 — neuroscience — Posted on 2023-06-22

1380 Neuronal alterations in AKT isotype expression in schizophrenia

Devine, E.; Joyce, A.; Imami, A.; Hammoud, A.; Golchin, H.; Eby, H.; Shedroff, E.; Asha, S.; Walssbass, C.; O'Donovan, S. M.; Smith, R.

10.1101/2023.06.19.545479 — neuroscience — Posted on 2023-06-22

1381 Investigating apparent differences between standard DKI and axisymmetric DKI and its consequences for biophysical parameter estimates

Oeschger, J. M.; Tabelow, K.; Mohammadi, S.

10.1101/2023.06.21.545891 — biophysics — Posted on 2023-06-22

1382 Soil carbon mineralization and microbial community dynamics in response to PyOM addition

Zeba, N.; Berry, T. D.; Fischer, M. S.; Traxler, M. F.; Whitman, T.

10.1101/2023.06.21.545992 — ecology — Posted on 2023-06-22

1383 Recombinase-Independent AAV for Anterograde Transsynaptic Tracing

Faress, I.; Khalil, V.; Yamamoto, H.; Sajgo, S.; Yonehara, K.; Nabavi, S.

10.1101/2023.06.20.545789 — neuroscience — Posted on 2023-06-22

1384 Light-exercise-induced dopaminergic and noradrenergic stimulation in the dorsal hippocampus: using a rodent physiological exercise model

Hiraga, T.; Hata, T.; Okamoto, M.; Soya, H.

10.1101/2023.06.19.545490 — neuroscience — Posted on 2023-06-22

1385 Polysulfide Nanoparticles Ameliorate Ischaemia Reperfusion Injury in Renal Transplantation and Improve Kidney Function Post-Transplantation

Stone, J. P.; D'Arcy, R.; Geraghty, A.; Amin, K.; Montero-Fernandez, A.; Dabare, D.; Ghibaudi, M.; Francini, N.; Coradello, G.; Bramhall, J.; Galwey, N. W.; Ruseva, M.; Tirelli, N.; Fildes, J.

10.1101/2023.06.21.545864 — synthetic biology — Posted on 2023-06-22

1386 Modeling the motion of disease-associated KIF1A heterodimers

Kita, T.; Sasaki, K.; Niwa, S.

10.1101/2023.06.22.546060 — biophysics — Posted on 2023-06-22

1387 Atomic description of supercoils and melting bubbles on linear DNA

Burman, M.; Noy, A.

10.1101/2023.06.21.545919 — biophysics — Posted on 2023-06-22

1388 Engineered CD47 protects T cells for enhanced antitumor immunity

Yamada-Hunter, S. A.; Theruvath, J.; McIntosh, B. J.; Freitas, K. A.; Radosevich, M. T.; Leruste, A.; Dhingra, S.; Martinez-Velez, N.; Xu, P.; Delaidelli, A.; Desai, M. H.; Good, Z.; Labanieh, L.; Mount, C. W.; Chen, Y.; Heitzeneder, S.; Marjon, K. D.; Banuelos, A.; Khan, O.; Huang, J.; Wasserman, S. L.; Spiegel, J. Y.; Fernandez-Pol, S.; Sorensen, P. H.; Monje, M.; Majzner, R. G.; Weissman, I. L.; Sahaf, B.; Sotillo, E.; Cochran, J. R.; Mackall, C. L.

10.1101/2023.06.20.545790 — bioengineering — Posted on 2023-06-22

1389 Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors

Neuman, S. S.; Metzger, J. M.; Bondarenko, V.; Wang, Y.; Felton, J.; Levine, J. E.; Saha, K.; Gong, S.; Emborg, M. E.

10.1101/2023.06.21.542185 — bioengineering — Posted on 2023-06-22

1390 snoRNA-guided tRNA 2'-O-methylation controls codon-biased gene expression and cellular states

Zhang, M.; Li, K.; Bai, J.; Van Damme, R.; Zhang, W.; Alba, M.; Stiles, B. L.; Chen, J.; Lu, Z.

10.1101/2023.06.22.546166 — biochemistry — Posted on 2023-06-22

1391 Structural Basis for Autoinhibition by the Dephosphorylated Regulatory Domain of Ycf1

Khandelwal, N. K.; Tomasiak, T. M.

10.1101/2023.06.22.546176 — biochemistry — Posted on 2023-06-22

1392 Cortical tension regulates Hippo signaling via Par-1-mediated Kibra degradation

Tokamov, S. A.; Buiter, S.; Ullyot, A.; Scepanovic, G.; Williams, A. M.; Fernandez-Gonzalez, R.; Horne-Badovinac, S.; Fehon, R. G.

10.1101/2023.06.18.545491 — cell biology — Posted on 2023-06-22

1393 A pathogenic missense mutation in kainate receptors elevates dendritic excitability and synaptic integration through dysregulation of SK channels

Nomura, T.; Taniguchi, S.; Wang, Y.-Z.; Yeh, N.-H.; Wilen, A. P.; Castillon, C. C. M.; Foote, K. M.; Xu, J.; Armstrong, J. N.; Savas, J. N.; Swanson, G. T.; Contractor, A.

10.1101/2023.06.21.545929 — neuroscience — Posted on 2023-06-22

1394 Small-field visual projection neurons detect translational optic flow and support walking control

Isaacson, M. D.; Eliason, J. L.; Nern, A.; Rogers, E. M.; Lott, G. K.; Tabachnik, T.; Rowell, W. J.; Edwards, A. W.; Korff, W. L.; Rubin, G. M.; Branson, K.; Reiser, M. B.

10.1101/2023.06.21.546024 — neuroscience — Posted on 2023-06-22

1395 Comprehensive analysis of network reconstruction approaches based on correlation in metagenomic data

Fuschi, A.; Merlotti, A.; Tran, D.-B.; Nguyen, H.; Weinstock, G.; Remondini, D.

10.1101/2023.06.20.545665 — systems biology — Posted on 2023-06-22

1396 A Common Pathway for Detergent-Assisted Oligomerization of Aβ42

Kunnath Muhammedkutty, F. N.; Prasad, R.; Gao, Y.; Rao Sudarshan, T.; Robang, A. S.; Watzlawik, J. O.; Rosenberry, T. L.; Paravastu, A. K.; Zhou, H.-X.

10.1101/2023.06.22.546091 — biophysics — Posted on 2023-06-22

1397 Probing the dissociation pathway of a kinetically labile transthyretin mutant

Sun, X.; Ferguson, J. A.; Leach, B. I.; Stanfield, R. L.; Dyson, H. J.; Wright, P. E.

10.1101/2023.06.21.545798 — biophysics — Posted on 2023-06-22

1398 Discovery, Characterization, and Bioactivity of the Achromonodins: Lasso Peptides Encoded by Achromobacter

Carson, D. V.; Zhang, Y.; So, L.; Cheung-Lee, W. L.; Cartagena, A. J.; Darst, S. A.; Link, A. J.

10.1101/2023.06.21.545946 — biochemistry — Posted on 2023-06-22

1399 Differential roles of diet on development and spinal cord regeneration in larval zebrafish

Puriofy, E. J.; Mruk, K.

10.1101/2023.06.20.545707 — developmental biology — Posted on 2023-06-22

1400 Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization

Tillery, M. M. L.; Zheng, C.; Zheng, Y.; Megraw, T. L.

10.1101/2023.06.22.546109 — cell biology — Posted on 2023-06-22

1401 Effects of TP63 Mutations on Keratinocyte Adhesion and Migration

Salois, M. N.; Gugger, J. A.; Webb, S.; Sheldon, C. E.; Parraga, S. P.; Lewitt, G. M.; Grange, D. K.; Koch, P. J.; Koster, M. I.

10.1101/2023.05.04.539104 — cell biology — Posted on 2023-06-22

1402 Characterization of Tigurilysin, a Novel Human CD59-Specific Cholesterol-Dependent Cytolysin, Reveals a Role for Host Specificity in Augmenting Toxin Activity

Shahi, I.; Dongas, S.; Ilmain, J. K.; Torres, V. J.; Ratner, A. J.

10.1101/2023.06.21.545930 — microbiology — Posted on 2023-06-21

1403 Localist versus distributed representation of sounds in the auditory cortex controlled by distinct inhibitory neuronal subtypes.

Tobin, M.; Sheth, J. N.; Wood, K. C.; Geffen, M. N.

10.1101/2023.02.01.526470 — neuroscience — Posted on 2023-06-22

1404 Cholinergic modulation supports dynamic switching of resting state networks through selective DMN suppression

Sanda, P.; Hlinka, J.; van den Berg, M.; Skoch, A.; Bazhenov, M.; Keliris, G. A.; Krishnan, G.

10.1101/2022.11.01.514686 — neuroscience — Posted on 2023-06-22

1405 Astrocyte Ca2+ signalling mediates long-distance metaplasticity in the hippocampal CA1

Jones, O. D.; Singh, A.; Logan, B.; Abraham, W.

10.1101/2023.06.19.545623 — neuroscience — Posted on 2023-06-22

1406 A systematic review of the diversity and virulence correlates of metastrongyle lungworms in marine mammals

Fischbach, J. R.; Seguel, M. A.

10.1101/2023.02.03.527020 — pathology — Posted on 2023-06-22

1407 Predominant myosin super-relaxed state in canine myocardium with naturally occurring dilated cardiomyopathy

Ochala, J.; Lewis, C. T. A.; Beck, T.; Iwamoto, H.; Hessel, A.; Campbell, K.; Pyle, G.

10.1101/2023.03.10.532046 — pathology — Posted on 2023-06-22

1408 Kinetics of zoospores approaching a root using a microfluidic device

Cohen, C.; Gauci, F.-X.; Noblin, X.; Galiana, E.; Attard, A.; Thomen, P.

10.1101/2023.06.21.545863 — biophysics — Posted on 2023-06-22

1409 Loops are Geometric Catalysts for DNA Integration

Battaglia, C.; Michieletto, D.

10.1101/2023.06.21.545982 — biophysics — Posted on 2023-06-22

1410 Comprehensive annotation of 3'UTRs from primary cells and their quantification from scRNA-seq data

Fansler, M. M.; Mitschka, S.; Mayr, C.

10.1101/2021.11.22.469635 — bioinformatics — Posted on 2023-06-22

1411 Pharmacokinetic profile of the synthetic mu-opioid receptor agonist Dermorphin-IRDye(R)800CW and its feasibility as a biomarker for opioid use disorder

Samkoe, K. S.; Strawbridge, R. R.; Spaller, M. R.; Pletnev, A. A.; Wirth, D. J.; Byrd, B. K.; Meng, B.; Sottosanti, J. S.; Davis, S. C.; Elliott, J. T.

10.1101/2023.06.19.545627 — bioengineering — Posted on 2023-06-22

1412 SCFFBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation.

Jin, B.; Moududee, S. A.; Ge, D.; Liu, Y.; Wang, A. R.; Zhou, P.; You, Z.

10.1101/2023.06.21.545972 — biochemistry — Posted on 2023-06-22

1413 Site-specific acetylation of polynucleotide kinase 3-phosphatase (PNKP) regulates its distinct role in DNA repair pathways

Islam, A.; Chakraborty, A.; Sarker, A. H.; Aryal, U. K.; Sharma, G.; Boldogh, I.; Hazra, T.

10.1101/2023.06.21.545973 — biochemistry — Posted on 2023-06-22

1414 Stuck on a small tropical island: wide in-situ diversification of an urban-dwelling bat

Aguillon, S.; Castex, C.; Duchet, A.; Turpin, M.; Le Minter, G.; Lebarbenchon, C.; Hoarau, A. O. G.; Toty, C.; Joffrin, L.; Tortosa, P.; Mavingui, P.; Goodman, S. M.; Dietrich, M.

10.1101/2023.06.22.546033 — genetics — Posted on 2023-06-22

1415 Maternal regulation of the vertebrate oocyte-to-egg transition

Fuentes, R.; Marlow, F.; Abrams, E.; Zhang, H.; Kobayashi, M.; Gupta, T.; Kapp, L.; DiNardo, Z.; Montecinos-Franjola, F.; Vought, W.; Vejnar, C.; Giraldez, A. E.; Mullins, M. C.

10.1101/2023.06.22.546137 — developmental biology — Posted on 2023-06-22

1416 Cellular insights of beech leaf disease reveal abnormal ectopic cell division of symptomatic interveinal leaf areas

Vieira, P.; Kantor, M. R.; Jansen, A.; Handoo, Z.; Eisenback, J. D.

10.1101/2023.06.22.546113 — cell biology — Posted on 2023-06-22

1417 Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence

Soha, S. A.; Santhireswaran, A.; Huq, S.; Casimir-Powell, J.; Jenkins, N.; Hodgson, G. K.; Sugiyama, M.; Antonescu, C. N.; Impellizzeri, S.; Botelho, R. J.

10.1101/2022.04.26.489585 — cell biology — Posted on 2023-06-22

1418 Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

Parra Bravo, C.; Giani, A. M.; Madero-Perez, J.; Zhao, Z.; Samelson, A. J.; Wong, M. Y.; Evangelisti, A.; Fan, L.; Pozner, T.; Mercedes, M.; Ye, P.; Patel, T.; Yarahmady, A.; Carling, G.; Lee, V. M. Y.; Sharma, M.; Mok, S.-A.; Luo, W.; Zhao, M.; Kampmann, M.; Gong, S.; Gan, L.

10.1101/2023.06.19.544278 — neuroscience — Posted on 2023-06-22

1419 Biochemical and chemical biological approaches to mammalian sleep: roles of calcineurin in site-specific dephosphorylation and sleep regulation

Yu, J.; Wang, T. V.; Gao, R.; Li, C.; Liu, H.; Yang, L.; Liu, Y.; Cui, Y.; Chen, P. R.; Rao, Y.

10.1101/2023.06.19.545643 — neuroscience — Posted on 2023-06-22

1420 Predicting causal citations without full text

Hoppe, T. A.; Arabi, S.; Hutchins, B. I.

10.1101/2022.07.05.498860 — scientific communication and education — Posted on 2023-06-22

1421 Multichannel joint image reconstruction allows for artifact-free focused small field of view magnetic particle imaging

Gevaert, J. J.; Konkle, J.; Goodwill, P.; Foster, P. J.

10.1101/2023.06.22.545970 — biophysics — Posted on 2023-06-22

1422 A benchmark study of data normalisation methods for PTR-TOF-MS exhaled breath metabolomics

Roquencourt, C.; Lamy, E.; Bardin, E.; Devillier, P.; Grassin-Delyle, S.

10.1101/2023.06.22.546053 — bioinformatics — Posted on 2023-06-22

1423 Visualizing hemoglobin oxygen saturation distribution in small animals: an in vivo application of a 3D photoacoustic imaging scanner with a hemispherical detector array

Asao, Y.; Hirano, R.; Nagae, K.; Sekiguchi, H.; Aiso, S.; Watanabe, S.; Sato, M.; Yagi, T.; Kondoh, S. K.

10.1101/2023.06.19.545650 — bioengineering — Posted on 2023-06-22

1424 Design and Evaluation of an Affordable Hypoxic Chamber with Comprehensive Environmental Control for Research Applications

Roshan, S. A.; Swaminathan, J.; Kandasamy, M.; Muthuswamy, A.

10.1101/2023.06.21.546032 — bioengineering — Posted on 2023-06-22

1425 Motoneuron-driven computational muscle modelling with motor unit resolution and subject-specific musculoskeletal anatomy

Caillet, A. H.; Phillips, A. T.; Farina, D.; Modenese, L.

10.1101/2023.06.03.543552 — bioengineering — Posted on 2023-06-22

1426 Stability of Alternative Bacteriorhodopsin Folds

Mackin, K. A.; Theobald, D. L.

10.1101/2023.06.21.545983 — biochemistry — Posted on 2023-06-22

1427 Structural Elucidation of Intact Rough-Type Lipopolysaccharides using Field Asymmetric Ion Mobility Spectrometry and Kendrick Mass Defect Plots

Mikhael, A.; Hardie, D.; Smith, D.; Petrosova, H.; Ernst, R. K.; Goodlett, D. R.

10.1101/2023.06.21.545950 — biochemistry — Posted on 2023-06-22

1428 Multiprotein Assemblies, Phosphorylation and Dephosphorylation in Neuronal Cytoskeleton

Kurochkina, N. A.; Sapio, M. R.; Iadarola, M. J.; Hall, B. E.; Kulkarni, A.

10.1101/2023.06.21.545989 — biochemistry — Posted on 2023-06-22

1429 Assessment of Nutrient Composition and utilization of some popular wild Edible fruits of Kumaun Himalayan Region as Anti-oxidant agents

Pandey, N.; Ghosh, P.; M, M. K.; Bisht, S. S.; JHA, A.

10.1101/2023.06.21.545978 — biochemistry — Posted on 2023-06-22

1430 Macromolecular Crowding Promotes Reentrant Liquid-Liquid Phase Separation of Human Serum Transferrin and Prevents Surface-Induced Fibrillation

Patel, C. K.; Rani, C.; Kumar, R.; Mukherjee, T. K.

10.1101/2023.06.21.545847 — biochemistry — Posted on 2023-06-22

1431 A widespread proteinaceous sulfur storage compartment in bacteria

Benisch, R.; Andreas, M. P.; Giessen, T. W.

10.1101/2023.06.21.545984 — biochemistry — Posted on 2023-06-22

1432 Multi-omics data and analysis reveal the formation of key pathways of different colors in Torenia fournieri flowers

Song, J.; Yang, P.

10.1101/2023.06.19.545640 — genomics — Posted on 2023-06-22

1433 Infection by the lungworm Rhabdias pseudosphaerocephala affects the expression of immune-related microRNAs by its co-evolved host, the cane toad Rhinella marina.

Chan, T. C. L.; Yagound, B.; Brown, G. P.; Eyck, H. J. F.; Shine, R.; Rollins, L. A.

10.1101/2023.06.19.545515 — genetics — Posted on 2023-06-22

1434 GATA-regulated transcriptional program dictate cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development

Ghosh, A.; Kumar, R.; Kumar, R. P.; Ray, S.; Saha, A.; Roy, N.; Dasgupta, P.; Marsh, C.; Paul, S.

10.1101/2023.06.19.545618 — developmental biology — Posted on 2023-06-22

1435 Characterization of the Oral Bacteriome of the Healthy Lewis Rat

Schramm, S. T.; DeCurtis, E.; Wheelis, S. E.; Jorgeson, I.; Rodrigues, D. B.; Palmer, K.

10.1101/2023.06.22.546140 — microbiology — Posted on 2023-06-22

1436 Multi-omics analysis of Bacillus. subtilis spores formed at different environmental temperatures reveal differences at the morphological and molecular level.

Huang, Y.; Roseboom, W.; Brul, S.; Kramer, G.

10.1101/2023.06.22.546136 — microbiology — Posted on 2023-06-22

1437 GABAergic LRP1 is a key link between obesity and memory function

Uner, A. A.; Hou, Z.-S.; Aydogan, A.; Rodrigues, K. C. d. C.; Young, J.; Choi, A.; Yang, W.-M.; Kim, W.; PREVOT, V.; Caldarone, B. J.; Lee, H.; Kim, Y.-B.

10.1101/2022.09.17.508390 — neuroscience — Posted on 2023-06-22

1438 RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

Seflova, J.; Schwarz, J. A.; Smith, A. N.; Svensson, B.; Blackwell, D. J.; Phillips, T. A.; Nikolaienko, R.; Bovo, E.; Rebbeck, R. T.; Zima, A. V.; Thomas, D. D.; Van Petegem, F.; Knollmann, B. C.; Johnston, J. N.; Robia, S. L.; Cornea, R. L.

10.1101/2023.06.22.546083 — biophysics — Posted on 2023-06-22

1439 Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD

Moochickal Assainar, B.; Ragunathan, K.; Baldridge, R.

10.1101/2023.06.20.545802 — biophysics — Posted on 2023-06-22

1440 Testing relationships between multiple regional features and biogeographic processes of speciation, extinction, and dispersal

Swiston, S. K.; Landis, M. J.

10.1101/2023.06.19.545613 — evolutionary biology — Posted on 2023-06-22

1441 Genomic and ecological factors shaping specialism and generalism across an entire subphylum

10.1101/2023.06.19.545611 — evolutionary biology — Posted on 2023-06-22

1442 Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo

Kordus, S. L.; Kroh, H. K.; Rodriguez, R. C.; Shrem, R. A.; Wadzinski, B. E.; Lacy, D. B.; Spiller, B. W.

10.1101/2023.06.21.545857 — microbiology — Posted on 2023-06-21

1443 The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes

Thomas, E. C. M.; Finnen, R. L.; Mewburn, J. D.; Archer, S. L.; Banfield, B. W.

10.1101/2023.06.21.545979 — microbiology — Posted on 2023-06-21

1444 Mechanism of DNA origami folding elucidated by mesoscopic simulations

DeLuca, M.; Ye, T.; Poirier, M. G.; Ke, Y.; Castro, C.; Arya, G.

10.1101/2023.06.20.545758 — biophysics — Posted on 2023-06-22

1445 Structural insights into a single semi-clathrate hydrate formed in a confined environment of porous protein crystal.

Maity, B.; Tian, J.; Furuta, T.; Abe, S.; Ueno, T.

10.1101/2023.06.21.546005 — biophysics — Posted on 2023-06-22

1446 Electrically Conductive DNA-Inspired Coating for Intracortical Neural Microelectrodes

Sands, I.; Ersöz, A.; Zhang, W.; Zhou, L.; Linthicum, W.; Santaniello, S.; Huey, B.; Han, M.; Chen, Y.

10.1101/2023.06.19.545632 — bioengineering — Posted on 2023-06-22

1447 CD95L concatemers highlight difference in the manner CD95-mediated apoptotic and non-apoptotic pathways are triggered.

Lebrault, E.; Oblet, C.; Kurma, K.; Levoin, N.; Jean, M.; Vacher, P.; LEGEMBRE, P.

10.1101/2023.06.22.546070 — biochemistry — Posted on 2023-06-22

1448 Omics Scale Quantitative Mass Spectrometry Imaging of Lipids in Brain Tissue using a Multi-Class Internal Standard Mixture

Vandenbosch, M.; Mutuku, S. M.; Mantas, M. J. Q.; Patterson, N. H.; Hallmark, T.; Claesen, M.; Heeren, R. M. A.; Hatcher, N. G.; Verbeeck, N.; Ekroos, K.; Ellis, S. R.

10.1101/2023.06.21.546027 — biochemistry — Posted on 2023-06-22

1449 A large-scale bioinformatic study of graspimiditides and structural characterization of albusimiditide

Choi, B.; Acuna, A.; Koos, J. D.; Link, A. J.

10.1101/2023.06.21.545981 — biochemistry — Posted on 2023-06-22

1450 Deep learning prediction of enzyme optimum pH

Gado, J. E.; Knotts, M.; Shaw, A. Y.; Marks, D.; Gauthier, N. P.; Sander, C.; Beckham, G. T.

10.1101/2023.06.22.544776 — biochemistry — Posted on 2023-06-22

1451 Bioorthogonal caging-group-free photoactivatable probes for minimal-linkage-error nanoscopy

Aktalay, A.; Lincoln, R.; Heynck, L.; Lima, M. A. D. R. B. F.; Butkevich, A. N.; Bossi, M. L.; Hell, S. W.

10.1101/2023.06.21.545866 — biochemistry — Posted on 2023-06-22

1452 Unraveling the mechanisms of PAMless DNA interrogation by SpRY Cas9

Hibshman, G. N.; Bravo, J. P.; Zhang, H.; Dangerfield, T. L.; Finkelstein, I. J.; Johnson, K. A.; Taylor, D. W.

10.1101/2023.06.22.546082 — biochemistry — Posted on 2023-06-22

1453 Unraveling the Genomic Diversity and Evolutionary History of Captive Tigers in the United States

Armstrong, E. E.; Mooney, J. A.; Solari, K. A.; Kim, B. Y.; Barsh, G. S.; Grant, V. B.; Greenbaum, G.; Kaelin, C. B.; Panchenko, K.; Pickrell, J. K.; Rosenberg, N.; Ryder, O. A.; Yokoyama, T.; Ramakrishnan, U.; Petrov, D. A.; Hadly, E. A.

10.1101/2023.06.19.545608 — evolutionary biology — Posted on 2023-06-22

1454 Ecological causes of uneven mammal diversity

Upham, N. S.; Esselstyn, J. A.; Jetz, W.

10.1101/504803 — evolutionary biology — Posted on 2023-06-22

1455 Group or solitary dispersal: worker presence and number favour the success of colony foundation in ants

Finand, B.; Loeuille, N.; Bocquet, C.; Federici, P.; Monnin, T.

10.1101/2023.06.20.545674 — ecology — Posted on 2023-06-22

1456 Robust axis elongation by Nodal-dependent restriction of BMP signaling

Schauer, A.; Pranjic-Ferscha, K.; Hauschild, R.; Heisenberg, C.-P.

10.1101/2023.06.19.545591 — developmental biology — Posted on 2023-06-22

1457 A genome-wide overexpression screen reveals Mycobacterium smegmatis growth inhibitors encoded by mycobacteriophage Hammy

Amaya, I.; Edwards, K.; Wise, B. M.; Bhattacharyya, A.; Pablo, C. H. D.; Mushrush, E.; Coats, A. N.; Dao, S.; Dittmar, G.; Gore, T.; Jarva, T. M.; Kenkebashvili, G.; Rathan-Kumar, S.; Reyes, G. M.; Watts, G. L.; Watts, V. K.; Dubrow, D.; Lewis, G. S.; Stone, B. H.; Xue, B.; Cresawn, S. G.; Mavrodi, D.; Sivanathan, V.; Heller, D.

10.1101/2023.06.21.545952 — microbiology — Posted on 2023-06-21

1458 Androgen exposure impairs neutrophil maturation and function within the infected kidney

Hreha, T. N.; Collins, C. A.; Hunstad, D. A.

10.1101/2023.06.19.545598 — immunology — Posted on 2023-06-22

1459 A Systems Level Explanation for Gompertzian Mortality Patterns is provided by the "Multiple and Inter-dependent Component Cause Model"

Nielsen, P. Y.; Jensen, M. K.; Mitarai, N.; Bhatt, S.

10.1101/2023.06.20.545709 — systems biology — Posted on 2023-06-22

1460 High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen

Yang, W.-p.; Li, M.-q.; Ding, J.; Li, J.-y.; Wu, G.; Liu, B.; Gao, Y.-q.; Wang, G.; Luo, Q.-q.

10.1101/2023.03.23.533972 — physiology — Posted on 2023-06-22

1461 WAS IT A MATch I SAW? Approximate palindromes lead to overstated false match rates in benchmarks using reversed sequences

Glidden-Handgis, G. E.; Wheeler, T. J.

10.1101/2023.06.19.545636 — bioinformatics — Posted on 2023-06-22

1462 The impact of non-lineage defining mutations inthe structural stability for variants of concern of SARS-CoV-2

Martins, Y. C.; Francisco, R. d. S.

10.1101/2023.06.22.546079 — bioinformatics — Posted on 2023-06-22

1463 Liquid Transmission Electron Microscopy for Probing Collagen Biomineralization

DiCecco, L.-A.; Gao, R.; Gray, J. L.; Kelly, D. F.; Sone, E. D.; Grandfield, K.

10.1101/2023.06.19.545614 — bioengineering — Posted on 2023-06-22

1464 Targeting the conserved active site of splicing machines with specific and selective small molecule modulators

Silvestri, I.; Manigrasso, J.; Andreani, A.; Brindani, N.; De Vivo, M.; Marcia, M.

10.1101/2023.06.21.545906 — biochemistry — Posted on 2023-06-22

1465 Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1

Rochon, K.; Bauer, B. L.; Roethler, N. A.; Buckley, Y.; Su, C.-C.; Huang, W.; Ramachandran, R.; Stoll, M. S. K.; Yu, E. W.; Taylor, D. J.; Mears, J. A.

10.1101/2023.06.22.546081 — cell biology — Posted on 2023-06-22

1466 Thermosensitivity of translation underlies the mammalian nocturnal-diurnal switch

Beale, A. D.; Rzechorzek, N. M.; Mihut, A.; Zeng, A.; Smyllie, N. J.; Pilorz, V.; Richardson, R.; Bertlesen, M. F.; James, N. R.; Fazal, S. V.; Voysey, Z.; Pelletier, J.; Crosby, P.; Peak-Chew, S. Y.; Lancaster, M. A.; Hut, R. A.; O'Neill, J. S.

10.1101/2023.06.22.546020 — cell biology — Posted on 2023-06-22

1467 Visual Motion Detection Thresholds Can Be Reliably Measured During Walking and Standing

DiBianca, S. J.; Jeka, J. J.; Reimann, H.

10.1101/2023.06.19.545323 — neuroscience — Posted on 2023-06-22

1468 Is EEG best left alone?

de Cheveigne, A.

10.1101/2023.06.19.545602 — neuroscience — Posted on 2023-06-22

1469 Monkeys exhibit human-like gaze biases in economic decisions

Lupkin, S. M.; McGinty, V. B.

10.1101/2022.02.24.481847 — neuroscience — Posted on 2023-06-22

1470 Hunger- and thirst-sensing neurons modulate a neuroendocrine network to coordinate sugar and water ingestion

Gonzalez-Segarra, A. J.; Pontes, G.; Jourjine, N.; Del Toro, A.; Scott, K.

10.1101/2023.04.06.535891 — neuroscience — Posted on 2023-06-22

1471 Between-area communication through the lens of within-area neuronal dynamics

Gozel, O.; Doiron, B.

10.1101/2022.04.11.487906 — neuroscience — Posted on 2023-06-22

1472 Spatial connectivity and marine disease dispersal: missing links in aquaculture carrying capacity debates

Schmittmann, L.; Busch, K.; Kluger, L. C.

10.1101/2023.06.20.545704 — systems biology — Posted on 2023-06-22

1473 A neural-mechanistic hybrid approach improving the predictive power of genome-scale metabolic models

Faure, L.; Mollet, B.; Liebermeister, W.; Faulon, J.-L.

10.1101/2022.01.09.475487 — systems biology — Posted on 2023-06-22

1474 Massively integrated coexpression analysis reveals transcriptional regulation, evolution and cellular implications of the noncanonical translatome

Rich, A.; Acar, O.; Carvunis, A.-R.

10.1101/2023.03.16.533058 — systems biology — Posted on 2023-06-22

1475 Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells

Brunet, L.; Alexandre, D.; Lee, J.; Blanquer-Rossello, M. d. M.; Guernet, A.; Chhouri, H.; Kherrouche, Z.; Arabo, A.; Yao, S.; Godefroy, D.; Dehedin, J.; Li, J.-R.; Duparc, C.; Jamme, P.; Vinchent, A.; Berard, C.; Tulasne, D.; Arena, S.; Bardelli, A.; Cheng, C.; Cho, B. C.; Coulouarn, C.; Aaronson, S.; Cortot, A. B.; Anouar, Y.; Grumolato, L.

10.1101/2023.06.19.545595 — cancer biology — Posted on 2023-06-22

1476 CellStitch: 3D Cellular Anisotropic Image Segmentation via Optimal Transport

Liu, Y.; Jin, Y.; Azizi, E.; Blumberg, A. J.

10.1101/2023.06.19.545594 — bioinformatics — Posted on 2023-06-22

1477 Sulfate limitation increases specific plasmid DNA yield in E. coli fed-batch processes

Gotsmy, M.; Strobl, F.; Weiss, F.; Gruber, P.; Kraus, B.; Mairhofer, J.; Zanghellini, J.

10.1101/2023.02.09.527815 — bioengineering — Posted on 2023-06-22

1478 Structural basis of Cas12a R-loop propagation on pathway to DNA cleavage

Strohkendl, I.; Moy, C.; Nguyen, A.-H.; Russell, R.; Taylor, D. W.

10.1101/2023.03.13.532460 — biochemistry — Posted on 2023-06-22

1479 Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill Required for Fertilization

10.1101/2023.06.22.546073 — cell biology — Posted on 2023-06-22

1480 Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization

Tillery, M. M. L.; Zheng, C.; Zheng, Y.; Megraw, T. L.

10.1101/2023.06.22.546109 — cell biology — Posted on 2023-06-22

1481 Constructing neural networks with pre-specified dynamics

Mininni, C. J.; Zanutto, B. S.

10.1101/2023.06.19.545607 — neuroscience — Posted on 2023-06-22

1482 Portable Arbitrary Pulse Generator for Driving μCoils for Micromagnetic Neurostimulation

Bloom, R. P.; Saha, R.; Sanger, Z.; Benally, O. J.; Wu, K.; Girolamo, A. d.; Low, W. C.; Netoff, T. I.; Wang, J.-P.

10.1101/2023.06.19.545512 — neuroscience — Posted on 2023-06-22

1483 The genetic and dietary landscape of the muscle insulin signalling network

van Gerwen, J.; Masson, S. W. C.; Cutler, H. B.; Diaz-Vegas, A.; Potter, M.; Stockli, J.; Madsen, S.; Nelson, M. E.; Humphrey, S. J.; James, D. E.

10.1101/2023.06.21.546001 — systems biology — Posted on 2023-06-22

1484 Synthetic Frizzled agonist and LRP antagonist for high-efficiency Wnt/β-catenin signaling manipulation in organoid cultures and in vivo

Dai, Q.; Wang, J.; Lin, Z.; Yu, D.; Yang, H.; Zhang, J.; Li, X.; Zeng, J.; Hu, H.; Ni, C.; Zhao, B.

10.1101/2023.06.21.545860 — synthetic biology — Posted on 2023-06-22

1485 Plant Expression Omnibus - a comparative transcriptomic database for 103 Archaeplastida

Koh, E.; Goh, W.; Villanueva, E.; Julca, I.; Mutwil, M.

10.1101/2023.06.22.546049 — plant biology — Posted on 2023-06-22

1486 Improved detection and phylogenetic analysis of plant proteins containing LysM domains.

Dallachiesa, D.; Aguilar, M.; Lozano, M. J.

10.1101/2023.06.21.545963 — plant biology — Posted on 2023-06-22

1487 The ALOG domain defines a new family of plant-specific transcription factors acting during Arabidopsis flower development

Rieu, P.; Beretta, V. M.; Caselli, F.; Thevenon, E.; Lucas, J.; Rizk, M.; Franchini, E.; Dumas, R.; Nanao, M. H.; Kater, M. M.; Dumas, R.; Zubieta, C.; Parcy, F.; Gregis, V.

10.1101/2023.06.21.545689 — plant biology — Posted on 2023-06-22

1488 Genomic characterization of a nematode tolerance locus in sugar beet

Sielemann, K.; Pucker, B.; Orsini, E.; Elashry, A.; Schulte, L.; Viehoever, P.; Mueller, A. E.; Schechert, A.; Weisshaar, B.; Holtgraewe, D.

10.1101/2023.06.22.546034 — plant biology — Posted on 2023-06-22

1489 Polyploidy enhances desiccation tolerance in the grass Microchloa caffra

Marks, R. A.; Delgado, P.; Makonya, G. M.; Cooper, K.; VanBuren, R.; Farrant, J. M.

10.1101/2023.06.20.545583 — plant biology — Posted on 2023-06-22

1490 Wound induced small-peptide mediated signalling cascade regulated by OsPSKR, dictates balance between growth and defense in rice

Harshith, C. Y.; Pal, A.; Chakraborty, M.; NAIR, A. K.; Raju, S.; Shivaprasad, P. V.

10.1101/2023.06.20.545841 — plant biology — Posted on 2023-06-22

1491 The molecular basis of parental conflict driven regulation of endosperm cellularization

Kohler, C.; Butel, N.; Qiu, Y.; Xu, W.; Santos-Gonzalez, J.

10.1101/2023.06.22.546051 — plant biology — Posted on 2023-06-22

1492 CRISPR/Cas9 generated MeSWEET10a mutants show reduced susceptibility to cassava bacterial blight and produce viable seed

Elliott, K.; Veley, K. M.; Jensen, G.; Gilbert, K. B.; Norton, J.; Kambic, L.; Yoder, M.; Weil, A.; Motomura-Wages, S.; Bart, R.

10.1101/2023.06.21.545993 — plant biology — Posted on 2023-06-22

1493 Why not both? A case study measuring cortisol and corticosterone in poison frogs

Westrick, S. E.; Paitz, R. T.; Fischer, E. K.

10.1101/2023.06.19.545597 — physiology — Posted on 2023-06-22

1494 A statistical method for image-mediated association studies discovers genes and pathways associated with four brain disorders

He, J.; Antonyan, L.; Zhu, H.; Li, Q.; Enoma, D.; Zhang, W.; Liu, A.; Cao, B.; MacDonald, E.; Arnold, P.; Long, Q.

10.1101/2023.06.16.545326 — bioinformatics — Posted on 2023-06-22

1495 Predicting the impact of rare variants on RNA splicing in CAGI6

Lord, J.; Jaramillo Oquendo, C.; Wai, H. A.; Douglas, A. G. L.; Bunyan, D. J.; Wang, Y.; Hu, Z.; Zeng, Z.; Danis, D.; Katsonis, P.; Williams, A.; Lichtarge, O.; Chang, Y.; Bagnall, R. D.; Mount, S. M.; Matthiasardottir, B.; Lin, C.; van Overeem Hansen, T.; Leman, R.; Martins, A.; Houdayer, C.; Krieger, S.; Bakolitsa, C.; Peng, Y.; Kamandula, A.; Radivojac, P.; Baralle, D.

10.1101/2023.06.20.545093 — bioinformatics — Posted on 2023-06-22

1496 ER-Mitochondria Contact Sites expand during mitosis

Yu, F.; Courjaret, R.; Elmi, A.; Hammad, A. S.; Fisher, M.; Terasaki, M.; Machaca, K.

10.1101/2023.06.22.546089 — cell biology — Posted on 2023-06-22

1497 Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

Mikhova, M.; Heyza, J. R.; Meek, K.; Schmidt, J. C.

10.1101/2023.06.22.546088 — cell biology — Posted on 2023-06-22

1498 Advanced methodology for bacterial colonization of 3D organotypic epidermal models: a gateway to long-term host-microbe interaction and intervention studies

Rikken, G.; Meesters, L.; Jansen, P.; Rodijk-Olthuis, D.; van Vlijmen-Willems, I.; Niehues, H.; Olah, P.; Homey, B.; Schalkwijk, J.; Zeeuwen, P.; van den Bogaard, E.

10.1101/2023.06.21.545853 — microbiology — Posted on 2023-06-21

1499 Optimisation of a DNA extraction protocol for improving the bacterial and fungal classification based on Nanopore sequencing

Thu, M. S.; Sawaswong, V.; Chanchaem, P.; Klomkliew, P.; Campbell, B. J.; Hirankarn, N.; Fothergill, J. L.; Payungporn, S.

10.1101/2023.06.21.545968 — microbiology — Posted on 2023-06-21

1500 Lineage-specific intolerance to oncogenic drivers restricts histological transformation

Gardner, E. E.; Earlie, E. M.; Li, K.; Thomas, J.; Hubisz, M. J.; Stein, B. D.; Zhang, C.; Cantley, L. C.; Laughney, A. M.; Varmus, H.

10.1101/2023.06.21.545980 — cancer biology — Posted on 2023-06-22

1501 The molecular prognostic score, a classifier for risk stratification of high-grade serous ovarian cancer

Sarkar, S.; Saha, S. A.; Sarkar, P.; Banerjee, S.; Mitra, P.

10.1101/2023.06.19.545525 — genomics — Posted on 2023-06-21

1502 Immunorecognition of Streptococcus mutans secreted proteins protects against caries by limiting tooth adhesion

Bender, O.; Khoury, J.; Hirsch, G.; Weinberg, E.; Sagy, N.; Buller, S.; Lapides-Levy, S.; Blumer, S.; Bar, D. Z.

10.1101/2023.06.21.545893 — microbiology — Posted on 2023-06-21

1503 Valorization of Organic Fraction of Municipal Solid Waste Through Production of Volatile Fatty Acids (VFAs) and Biogas

Borhany, H.

10.1101/2023.06.21.545938 — microbiology — Posted on 2023-06-21

1504 Spatially clustered pattern of transcription factor binding reveals phase-separated transcriptional condensates at super-enhancers

Wang, Z.; Wang, S.; Zang, C.

10.1101/2023.06.18.545510 — genomics — Posted on 2023-06-21

1505 Comparative 3D genome analysis between neural retina and RPE reveals differential cis-regulatory interactions at retinal disease loci

D'haene, E.; Soriano, V. L.; Martinez-Garcia, P. M.; Kalayanamontri, S.; Rey, A. D.; Sousa-Ortega, A.; Naranjo, S.; Van de Sompele, S.; Vantomme, L.; Mahieu, Q.; Vergult, S.; Neto, A. B.; Gomez-Skarmeta, J. L.; Martinez-Morales, J. R.; Bauwens, M.; Tena, J. J.; De Baere, E.

10.1101/2023.06.20.543842 — genomics — Posted on 2023-06-21

1506 Murine Gammaherpesvirus 68 Efficiently Infects Myeloid Cells Resulting In An Atypical, Restricted Form Of Infection

Vragel, G.; Gomez, B. D.; Kostelecky, R. E.; Noell, K. S.; Tseng, A.; Cohen, S.; Dalwadi, M.; Medina, E. M.; Nail, E. A.; Goodspeed, A.; Clambey, E. T.; van Dyk, L. F.

10.1101/2023.06.21.545948 — microbiology — Posted on 2023-06-21

1507 Chronic Wound Milieu Challenges Essential Oils' Antibiofilm Activity

Brozyna, M.; Kozlowska, W.; Malec, K.; Paleczny, J.; Detyna, J.; Fabianowska-Majewska, K.; Junka, A. F.

10.1101/2023.06.21.545846 — microbiology — Posted on 2023-06-21

1508 VISTA: Visualizing the Spatial Transcriptome of the C. elegans Nervous System

Liska, D.; Wolfe, Z.; Norris, A. D.

10.1101/2023.04.28.538711 — bioinformatics — Posted on 2023-06-22

1509 Pangenome genotyped structural variation improves molecular phenotype mapping in cattle

Leonard, A. S.; Mapel, X. M.; Pausch, H.

10.1101/2023.06.21.545879 — genomics — Posted on 2023-06-21

1510 High-quality haploid genomes corroborate 29 chromosomes and highly conserved synteny of genes in Hyles hawkmoths (Lepidoptera: Sphingidae)

Hundsdoerfer, A. K.; Schell, T.; Patzold, F.; Wright, C.; Yoshido, A.; Marec, F.; Daneck, H.; Winkler, S.; Greve, C.; Podsiadlowski, L.; Hiller, M.; Pippel, M.

10.1101/2022.04.08.487644 — genomics — Posted on 2023-06-22

1511 DANGER analysis: Risk-averse on/off-target assessment for CRISPR editing without a reference genome

Nakamae, K.; Bono, H.

10.1101/2023.03.11.531115 — genomics — Posted on 2023-06-22

1512 DYNATE: Localizing Rare-Variant Association Regions via Multiple Testing Embedded in an Aggregation Tree

Li, X.; Pura, J.; Allen, A.; Owzar, K.; Lu, J.; Harms, M.; Xie, J.

10.1101/2022.12.01.518706 — genetics — Posted on 2023-06-21

1513 Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.

Richard, E.; Darracq, B.; Littner, E.; Vit, C.; Whiteway, C.; Bos, J.; Fournes, F.; Garriss, G.; Conte, V.; Lapaillerie, D.; Parissi, V.; Rousset, F.; Skovgaard, O.; Bikard, D.; Rocha, E.; Mazel, D.; Loot, C.

10.1101/2022.08.03.502626 — genetics — Posted on 2023-06-22

1514 Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis

Guicharnaud, C.; Groussier, G.; Beranger, E.; Lamy, L.; Vercken, E.; Dahirel, M.

10.1101/2023.01.24.525360 — ecology — Posted on 2023-06-22

1515 Habitual ground nesting in the Bugoma Forest chimpanzees (Pan troglodytes schweinfurthii), Uganda.

Hobaiter, C.; Klein, H.; Gruber, T.

10.1101/2022.12.14.520400 — ecology — Posted on 2023-06-22

1516 Reproductive success mediates the effects of climate change and grassland management on plant populations dynamics

Andrzejak, M.; Knight, T.; Plos, C.; Korell, L.

10.1101/2023.04.26.538388 — ecology — Posted on 2023-06-22

1517 IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A

Gebert, M.; Bartoszewska, S.; Opalinski, L.; Collawn, J.; Bartoszewski, R.

10.1101/2023.06.21.545854 — cell biology — Posted on 2023-06-22

1518 Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice

10.1101/2023.06.21.543373 — microbiology — Posted on 2023-06-21

1519 Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis.

Brunner, V.; Fowler, P. W.

10.1101/2023.06.21.545231 — microbiology — Posted on 2023-06-21

1520 Impact and role of hypothalamic corticotropin releasing hormone neurons in withdrawal from chronic alcohol consumption in female and male mice.

Neira, S.; Lee, S.; Hassanein, L.; Sides, T.; D'Ambrosio, S.; Boyt, K. M.; Bains, J. S.; Kash, T. L.

10.1101/2023.05.30.542746 — neuroscience — Posted on 2023-06-22

1521 Exploring the interactome of PML nuclear subdomains during fatty acid stress using APEX2-mediated proximity labeling

Thompson, J.; Boisvert, F.-M.; Salsman, J.; Dellaire, G.; Ridgway, N. D.

10.1101/2023.06.21.545954 — cell biology — Posted on 2023-06-22

1522 An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

He, K.; Sun, X.; Chen, C.; Luc, S.; Hao, J.; Zhang, Y.; Huang, Y.; Wang, H.; Ling, K.; Hu, J.

10.1101/2023.06.22.546046 — cell biology — Posted on 2023-06-22

1523 Basement membrane diversification relies on two competitive secretory routes defined by Rab10 and Rab8 and modulated by dystrophin and the exocyst complex

Dennis, C.; Pouchin, P.; Richard, G.; Mirouse, V.

10.1101/2023.03.22.533752 — cell biology — Posted on 2023-06-22

1524 Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos

Fang, J.; Kang, B. G.; Kam, T.-I.; Behensky, A.; Rines, J.; Kang, H. C.; Dawson, V. L.; Dawson, T.

10.1101/2023.06.18.545460 — cell biology — Posted on 2023-06-22

1525 Co-occurrence of ST412 Klebsiella pneumoniae isolates with hypermucoviscous and no-mucoviscous phenotypes in a short-term hospitalized patient

Liang, Q.; Zhang, B.; Wang, W.; Chen, N.; Luo, J.; Zhong, Y.; Zhang, F.; Zhang, Z. K.; Martin-Rodriguez, A. J.; Wang, Y.; Xiang, L.; Zhuang, J.; Hu, R.; Zhou, Y.

10.1101/2023.06.20.545774 — microbiology — Posted on 2023-06-22

1526 Scanning ultrasound improves memory and enhances functional outcomes in Alzheimer mice in the absence of amyloid-beta reduction

Leinenga, G.; To, X. V.; Bodea, L.-G.; Yousef, J.; Richter-Stretton, G.; Palliyaguru, T.; Chicoteau, A.; Dagley, L.; Nasrallah, F.; Gotz, J.

10.1101/2023.06.16.545394 — neuroscience — Posted on 2023-06-21

1527 TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells

Wuenkhaus, D.; Tang, R.; Nyame, K.; Laqtom, N. N.; Schweizer, M.; Rosato, A. S.; Kroegsaeter, E. K.; Wollnik, C.; Abu-Remaileh, M.; Grimm, C.; Hermey, G.; Kuhn, R.; Gruber-Schoffnegger, D.; Markmann, S.

10.1101/2023.06.21.545896 — cell biology — Posted on 2023-06-22

1528 Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1α

Simpson, M. S.; De Luca, H.; Cauthorn, S.; Luong, P.; Udeshi, N.; Svinkina, T.; Schmeider, S. S.; Carr, S. A.; Grey, M. J.; Lencer, W. I.

10.1101/2023.06.20.545791 — cell biology — Posted on 2023-06-22

1529 Ubiquitination is a novel post-translational modification of VMP1 in autophagy of human tumor cells

Renna, F. J.; Steinberg, J. H. E.; Gonzalez, C. D.; Manifava, M.; Tadic, M. S.; Orquera, T.; Vecino, C. V.; Ropolo, A.; Guardavaccaro, D.; Rossi, M.; Ktistakis, N. T.; Vaccaro, M. I.

10.1101/2023.02.13.528037 — cell biology — Posted on 2023-06-22

1530 Dynamic X-chromosomal reactivation enhances female brain resilience

Kaeseberg, S.; Bertin, M.; Menon, R.; Gabassi, E.; Todorov, H.; Frank, S.; Brennenstuhl, H.; Lohrer, B.; Winter, J.; Krummeich, J.; Winkler, J.; Winner, B.; Weis, E.; Hartwich, D.; Diederich, S.; Luck, K.; Gerber, S.; Lunt, P.; Berninger, B.; Falk, S.; Schweiger, S.; Karow, M.

10.1101/2023.06.17.545424 — neuroscience — Posted on 2023-06-21

1531 Dynamic noise estimation: A generalized method for modeling noise in sequential decision-making behavior

Li, J.-J.; Shi, C.; Li, L.; Collins, A.

10.1101/2023.06.19.545524 — neuroscience — Posted on 2023-06-22

1532 Analysis of NIH K99/R00 Awards and the Career Progression of Awardees

Woitowich, N. C.; Hengel, S. R.; Vilgalys, T. P.; Babdor, J.; Tyrrell, D. J.

10.1101/2023.01.26.525751 — scientific communication and education — Posted on 2023-06-22

1533 Cyclin A/cdk activity and FAM122A-dependent inhibition of PP2A-B55 are essential to trigger mitosis.

Lacroix, B.; Vigneron, S.; Labbé, J. C.; Pintard, L.; Labesse, G.; Castro, A.; Lorca, T.

10.1101/2023.06.20.545672 — cell biology — Posted on 2023-06-22

1534 Centriole elimination during C. elegans oogenesis initiates with loss of the central tube protein SAS-1

Pierron, M.; Woglar, A.; Busso, C.; Jha, K.; Mikeladze-Dvali, T.; Croisier, M.; Gönczy, P.

10.1101/2023.06.19.545600 — cell biology — Posted on 2023-06-22

1535 Folliculogenesis and ovulation in fish are controlled by distinct neuropeptides

Hollander cohen, L.; Shulman, M.; Fontanaud, P.; Revah, O.; Mollard, P.; Golan, M.; Levavi Sivan, B.

10.1101/2023.06.18.545454 — neuroscience — Posted on 2023-06-21

1536 A distinct neural activity subspace for direct motor cortical influence on muscles

Koh, N.; Ma, Z.; Sarup, A.; Kristl, A. C.; Agrios, M.; Young, M.; Miri, A.

10.1101/2023.06.18.545509 — neuroscience — Posted on 2023-06-22

1537 Dual proteomic signature of immune cells and Yersinia pestis upon blood infection

Le-Bury, P.; Douche, T.; Giai Gianetto, Q.; Matondo, M.; Pizarro-Cerda, J.; Dussurget, O.

10.1101/2023.06.19.545537 — systems biology — Posted on 2023-06-22

1538 Structural foundation for the role of enterococcal PrgB in conjugation, biofilm formation and virulence

Sun, W.-S.; Lassinantti, L.; Jarva, M.; Schmitt, A.; ter Beek, J.; Berntsson, R. P.-A.

10.1101/2022.10.21.513195 — biochemistry — Posted on 2023-06-22

1539 Single cell compendium of the muscle microenvironment in peripheral artery disease reveals capillary endothelial heterogeneity and activation of resident macrophages

Turiel, G.; Desgeorges, T.; Masschelein, E.; Birrer, M.; Zhang, J.; Engelberger, S.; De Bock, K.

10.1101/2023.06.21.545899 — cell biology — Posted on 2023-06-22

1540 Functional interaction of torsinA and its activators in liver lipid metabolism

Hernandez-Ono, A.; Zhao, Y. P.; Murray, J. M.; Ostlund, C. A.; Lee, M. J.; Ginsberg, H. N.; Worman, H. J.; Shin, J.-Y.

10.1101/2023.06.21.545957 — cell biology — Posted on 2023-06-22

1541 Place field precision during an episode predicts place field fate across episodes

Chiu, Y.; Dong, C.; Krishnan, S.; Sheffield, M. M. E.

10.1101/2023.06.18.545503 — neuroscience — Posted on 2023-06-21

1542 Grid Codes versus Multi-Scale, Multi-Field Place Codes for Space

Dietrich, R.; Waniek, N.; Stemmler, M.; Knoll, A. C.

10.1101/2023.06.18.545252 — neuroscience — Posted on 2023-06-21

1543 Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of stem cell and oncogenic programs

Alvarez-Villanueva, D.; Galan, L.; Bertran, j.; Floor, M.; Sole, L.; Lobo-Jarne, T.; Maqueda, M.; Rajbhandari, R.; Marruecos, L.; Villa, J.; Bredel, M.; Bigas, A.; Espinosa, L.

10.1101/2023.06.21.545928 — cell biology — Posted on 2023-06-22

1544 Membrane contact sites regulate vacuolar fission via sphingolipid metabolism

Hanaoka, K.; Nishikawa, K.; Ikeda, A.; Schlarmann, P.; Yamashita, S.; Nakaji, A.; Fujii, S.; Funato, K.

10.1101/2023.06.21.546015 — cell biology — Posted on 2023-06-22

1545 Drowsiness during resting-state fMRI: a major confounder of functional connectivity

Joliot, M.; Cremona, S.; Tzourio, C.; Etard, O.

10.1101/2023.06.19.545521 — neuroscience — Posted on 2023-06-21

1546 Early life adversities affect expected value signaling in the adult brain

Sacu, S.; Dubois, M.; Aggensteiner, P.-M.; Monninger, M.; Brandeis, D.; Banaschewski, T.; Hauser, T. U.; Holz, N.

10.1101/2023.06.19.545539 — neuroscience — Posted on 2023-06-21

1547 The essential inter-domain interaction between NUDT9H and channel domain of human TRPM2 is also accomplished in trans

Ehrlich, W.; Kuehn, F. J. P.

10.1101/2023.06.21.545868 — cell biology — Posted on 2023-06-22

1548 Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen.

Sharninghausen, R.; Hwang, J.; Dennison, D.; Baldridge, R.

10.1101/2023.06.21.546000 — cell biology — Posted on 2023-06-22

1549 Increased reliance on temporal coding when target sound is softer than the background

Alamatsaz, N.; Rosen, M. J.; Ihlefeld, A.

10.1101/2023.06.19.545590 — neuroscience — Posted on 2023-06-21

1550 A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types

Tibi, M.; Biton, S.; Hochgerner, H.; Lin, Z.; Givon, S.; Ophir, O.; Shay, T.; Mueller, T.; Segev, R.; Zeisel, A.

10.1101/2023.06.19.545605 — neuroscience — Posted on 2023-06-21

1551 Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis

Wiese, C.; Abele, M.; Al, B.; Altmann, M.; Steiner, A.; Kalbfuss, N.; Strohmayr, A.; Ravikumar, R.; Park, C. H.; Brunschweiger, B.; Meng, C.; Facher, E.; Ehrhardt, D. W.; Falter-Braun, P.; Wang, Z.-Y.; Ludwig, C.; Assaad, F. F.

10.1101/2023.04.24.537966 — plant biology — Posted on 2023-06-22

1552 EquiScore: A generic protein-ligand interaction scoring method integrating physical prior knowledge with data augmentation modeling

Cao, D.; Chen, G.; Jiang, J.; Yu, J.; Zhang, R.; Chen, M.; Zhang, W.; Chen, L.; Zhong, F.; Zhang, Y.; Lu, C.; Li, X.; Luo, X.; Zhang, S.; Zheng, M.

10.1101/2023.06.18.545464 — bioinformatics — Posted on 2023-06-22

1553 Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function.

Dacheux, D.; Martinez, G.; Broster Reix, C. E.; Beurois, J.; Tounkara, M.; Dupuy, J.-W.; Robinson, D. R.; Loeuillet, C.; Lambert, E.; Wehbe, Z.; Escoffier, J.; Amiri-Yekta, A.; Daneshipour, A.; Hosseini, S.-H.; Zouari, R.; Fourati Ben Mustapha, S.; Halouani, L.; Jiang, X.; Shen, Y.; Liu, C.; Thierry-Mieg, N.; Septier, A.; Bidart, M.; Satre, V.; Cazin, C.; Kherraf, Z.-E.; Arnoult, C.; Ray, P. F.; Toure, A.; Bonhivers, M.; Coutton, C.

10.1101/2023.03.07.531490 — genetics — Posted on 2023-06-22

1554 Need for cognition moderates cognitive effort aversion

Gheza, D.; Kool, W.; Pourtois, G.

10.1101/2023.06.20.545770 — neuroscience — Posted on 2023-06-21

1555 Drebrin Regulates Collateral Axon Branching in Cortical Layer II/III Somatosensory Neurons

Dorskind, J. M.; Sudarsanam, S.; Hand, R. A.; Ziak, J.; Amoah-Dankwah, M.; Guzman-Clavel, L.; Soto-Vargas, J. L.; Kolodkin, A. L.

10.1101/2023.06.21.545958 — neuroscience — Posted on 2023-06-21

1556 An EGF-modified PLGA-lanthanide nano platform for combined NIR-II cancer imaging and targeted drug delivery

He, Y.; Yu, z.; Schomann, T.; Zhang, H.; Eich, C.; Cruz, L. j.

10.1101/2023.06.18.545497 — cancer biology — Posted on 2023-06-21

1557 Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer

Blanchard, Z.; Rush, C. M.; Arnesen, S.; Vahrenkamp, J. M.; Rodriguez, A. C.; Jarboe, E. A.; Brown, C.; Chang, M. E. K.; Flory, M. R.; Mohammed, H.; Modzelewska, K.; Lum, D. H.; Gertz, J.

10.1101/2022.06.13.495977 — cancer biology — Posted on 2023-06-21

1558 Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

Tanaka, M.; Lum, L.; Hu, K. H.; Ledezma-Soto, C.; Samad, B.; Superville, D. A.; Ng, K. M.; Adams, Z.; Kersten, K. H.; Fong, L.; Combes, A.; Krummel, M. F.; Reeves, M. Q.

10.1101/2023.04.25.538140 — cancer biology — Posted on 2023-06-21

1559 Large-scale phylogenomics uncovers a complex evolutionary history and extensive ancestral gene flow in an African primate radiation

Jensen, A.; Swift, F.; de Vries, D.; Beck, R.; Kuderna, L. F. K.; Knauf, S.; Chuma, I. S.; Keyyu, J. D.; Kitchener, A. C.; Farh, K.; Rogers, J.; Marques-Bonet, T.; Detwiler, K. M.; Roos, C.; Guschanski, K.

10.1101/2023.06.21.545890 — evolutionary biology — Posted on 2023-06-22

1560 Stimulus-Specific Modulation is Enabled by Differential Serotonin Receptor Expression

Jonaitis, J.; Mazri, M. F. E. B.; Sizemore, T. R.; Ralston, J. D.; Salman, F.; Fletcher, E. J.; Matheny, D. E.; Ramachandra, K. L.; Dacks, A. M.

10.1101/2023.06.21.546011 — neuroscience — Posted on 2023-06-21

1561 A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank

Heise, V.; Offer, A.; Whiteley, W. N.; Mackay, C. E.; Armitage, J.; Parish, S.

10.1101/2023.06.19.543571 — neuroscience — Posted on 2023-06-21

1562 A geometrical framework for thinking about proteins

Banavar, J. R.; Giacometti, A.; Hoang, T. X.; Maritan, A.; Skrbic, T.

10.1101/2023.06.19.545540 — biophysics — Posted on 2023-06-21

1563 II. Geometrical framework for thinking about globular proteins: the power of poking

Skrbic, T.; Giacometti, A.; Hoang, T. X.; Maritan, A.; Banavar, J. R.

10.1101/2023.06.19.545553 — biophysics — Posted on 2023-06-21

1564 Defining cat mitogenome variation and accounting for numts via multiplex amplification and Nanopore sequencing

Patterson, E.; Matharu Lall, G.; Neumann, R.; Ottolini, B.; Sacchini, F.; Foster, A. P.; Jobling, M. A.; Wetton, J. H.

10.1101/2023.06.19.545568 — genetics — Posted on 2023-06-21

1565 CHPF boosts proliferation and invasion of clear cell renal cell carcinoma

Zhang, Y.; Li, X.; Ran, S.; Zhao, Y.; Huang, Y.; Zhou, T.; Wang, Q.; Liu, J.; Zhang, Q.; Li, X.; Leng, T.; Luo, Y.; Li, S.

10.1101/2023.06.09.544296 — genetics — Posted on 2023-06-21

1566 Comparative population genomics of manta rays has global implications for management

Humble, E.; Hosegood, J.; Carvalho, G.; de Bruyn, M.; Creer, S.; Stevens, G. M. W.; Armstrong, A.; Bonfil, R.; Deakos, M.; Fernando, D.; Froman, N.; Peel, L. R.; Pollett, S.; Ponzo, A.; Stewart, J. D.; Wintner, S.; Ogden, R.

10.1101/2023.06.19.545572 — evolutionary biology — Posted on 2023-06-21

1567 Gamma-Oscillation Plasticity Is Mediated by Parvalbumin Interneurons

Hadler, M. D.; Tzilivaki, A.; Schmitz, D.; Alle, H.; Geiger, J. R.

10.1101/2023.06.21.545901 — neuroscience — Posted on 2023-06-21

1568 The songbird lateral habenula projects to dopaminergic midbrain and is important for normal vocal development

Roeser, A. C.; Teoh, H. K.; Chen, R.; Goldberg, J. H.

10.1101/2023.06.21.545765 — neuroscience — Posted on 2023-06-21

1569 Systematic Characterization of LSD metabolites in C. elegans by ultra-high performance liquid chromatography coupled with high-resolution tandem mass spectrometry

Silveira, C. M. d. V.; dos Santos, V. F.; Ornelas, I. M.; Carrilho, B. d. S.; Ventura, M. A. V. d. C.; Pereira, H. M. G.; Rehen, S. K.; Junqueira, M.

10.1101/2023.06.19.545563 — pharmacology and toxicology — Posted on 2023-06-21

1570 Comprehensive computational analysis of the SRK-SP11 molecular interaction underlying self-incompatibility in Brassicaceae using improved structure prediction for cysteine-rich proteins

Sawa, T.; Moriwaki, Y.; Jiang, H.; Murase, K.; Takayama, S.; Shimizu, K.; Terada, T.

10.1101/2023.06.19.545538 — bioinformatics — Posted on 2023-06-21

1571 Seq-InSite: sequence supersedes structure for protein interaction site prediction

Hosseini, S.; Golding, G. B.; Ilie, L.

10.1101/2023.06.19.545575 — bioinformatics — Posted on 2023-06-21

1572 ThermoBRET: a ligand-engagement nanoscale thermostability assay applied to GPCRs

Hoare, B. L.; Tippett, D. N.; Kaur, A.; Cullum, S. A.; Miljus, T.; Koers, E. J.; Harwood, C. R.; Dijon, N.; Holliday, N. D.; Sykes, D. A.; Veprintsev, D. B.

10.1101/2020.08.05.237982 — biochemistry — Posted on 2023-06-21

1573 The dependence of forecasts on sampling frequency as a guide to optimizing monitoring in community ecology

Daugaard, U.; Merkli, S.; Merz, E.; Pomati, F.; Petchey, O. L.

10.1101/2023.06.19.545268 — ecology — Posted on 2023-06-21

1574 Geographic distribution of terpenoid chemotypes in Tanacetum vulgare mediates tansy aphid occurrence and abundance

Rahimova, H.; Neuhaus-Harr, A.; Clancy, M. V.; Guo, Y.; Junker, R. R.; Ojeda-Prieto, L.; Petren, H.; Senft, M.; Zytynska, S. E.; Weisser, W. W.; Heinen, R.; Schnitzler, J.-P.

10.1101/2023.06.19.545570 — ecology — Posted on 2023-06-21

1575 A multi-tiered mechanical mechanism shapes the early neural plate

Inman, A.; Lutton, J. E.; Spiritosanto, E.; Tada, M.; Bretschneider, T.; Haas, P. A.; Smutny, M.

10.1101/2023.06.21.545965 — developmental biology — Posted on 2023-06-21

1576 Measuring stimulus-related redundant and synergistic functional connectivity with single cell resolution in auditory cortex

Kocillari, L.; Celotto, M.; Francis, N. A.; Mukherjee, S.; Babadi, B.; Kanold, P. O.; Panzeri, S.

10.1101/2023.06.19.545531 — neuroscience — Posted on 2023-06-21

1577 Frequency modulation increases the specificity of time-resolved connectivity: A resting-state fMRI study

Faghiri, A.; Yang, K.; Ishizuka, K.; Sawa, A.; Adali, T.; Calhoun, V.

10.1101/2023.06.20.545786 — neuroscience — Posted on 2023-06-21

1578 Cross-species comparison of pregnancy-induced GDF15

Klein, A.; Ranea-Robles, P.; Nicolaisen, T.; Gil, C.; Johann, K.; Quesada, J.; Pistolevij, N.; Hviid, K.; Olsen, L.; Offersen, S.; Helge, J.; Svarre-Nielsen, H.; Bakker, J.; Kleinert, M.; Clemmensen, C.

10.1101/2023.06.19.545552 — physiology — Posted on 2023-06-21

1579 Systematic single-cell analysis reveals dynamic control of transposable element activity orchestrating the endothelial-to-hematopoietic transition

Feng, C.; Tie, R.; Xin, S.; Chen, Y.; Li, S.; Hu, X.; Zhou, Y.; Liu, Y.; Hu, Y.; Hu, Y.; Pan, H.; Wu, Z.; Chao, H.; Zhang, S.; Ni, Q.; Huang, J.; Luo, W.; Huang, H.; Chen, M.

10.1101/2023.06.19.545461 — bioinformatics — Posted on 2023-06-21

1580 InGene: Finding influential genes from embeddings of nonlinear dimension reduction techniques

Goswami, C.; Sengupta, D.

10.1101/2023.06.19.545592 — bioinformatics — Posted on 2023-06-21

1581 Packed hydrogel microfibers as a granular medium

Grewal, G. S.; Helein, G. T.; Sumey, J. L.; Caliari, S. R.; Highley, C. B.

10.1101/2023.06.19.545582 — bioengineering — Posted on 2023-06-21

1582 Dynamic skin signatures of cuttlefish internal states

Cohen Bodenes, S.; Neri, P.

10.1101/2023.06.19.545578 — animal behavior and cognition — Posted on 2023-06-21

1583 Insecticidal roof barriers mounted on untreated bednets can be as effective against Anopheles gambiae s.l. as insecticidal bednets

Abbott, A. J.; Matope, A.; Jones, J.; Voloshin, V.; Towers, C.; Towers, D.; McCall, P.

10.1101/2023.06.19.545532 — animal behavior and cognition — Posted on 2023-06-21

1584 Genetic drift vs natural selection affecting the evolution of spectral and functional traits of two key macrophytes: Phragmites australis and Nuphar lutea

Castellani, M. B.; Dalla Vecchia, A.; Bolpagni, R.; Natale, R.; Piaser, E.; Lastrucci, L.; Coppi, A.; Villa, P.

10.1101/2023.06.19.545543 — ecology — Posted on 2023-06-21

1585 A Dual Color Pax7 and Myf5 In Vivo Reporter to Investigate Muscle Stem Cell Heterogeneity in Regeneration and Aging

Ancel, S.; Michaud, J.; Sizzano, F.; Tauzin, L.; Oliveira, M.; Migliavacca, E.; Dammone, G.; Karaz, S.; Sanchez-Garcia, J. L.; Metairon, S.; Jacot, G.; Bentzinger, F. C.; Feige, J. N.; Stuelsatz, P.

10.1101/2023.06.19.545587 — cell biology — Posted on 2023-06-21

1586 Contralateral delay activity and alpha lateralization reflect retinotopic and screen-centered reference frames in visual memory

Moessing, W.; Schroeder, S. C.; Biel, A. L.; Busch, N. A.

10.1101/2023.06.19.545421 — neuroscience — Posted on 2023-06-21

1587 Future spinal reflex is embedded in primary motor cortex output

Umeda, T.; Yokoyama, O.; Suzuki, M.; Kaneshige, M.; Isa, T.; Nishimura, Y.

10.1101/2023.06.19.545500 — neuroscience — Posted on 2023-06-21

1588 Systematic biases in transcriptional parameters inferred from single-cell snapshot data

Grima, R.; Esmenjaud, P.-M.

10.1101/2023.06.19.545536 — systems biology — Posted on 2023-06-21

1589 Building methodological consensus to ensure rigor and reproducibility in zebrafish fertility research

Kossack, M. E.; Bowie, K.; Tian, L.; Plavicki, J.

10.1101/2023.06.19.545565 — pharmacology and toxicology — Posted on 2023-06-21

1590 Insights from the Early Cretaceous: The promise of Lycoptera aDNA sequencing

Zhao, W.; Guo, Z.; Tian, Z.; Su, T.; Cao, G.; Qi, Z.; Qin, T.; Zhou, W.; Yang, J.; Chen, M.; Zhang, X.; Zhou, C.; Zhu, C.; Tang, M.; Tang, M.; Wu, D.; Song, M.; Guo, Y.; Qiu, L.

10.1101/2023.06.18.545504 — paleontology — Posted on 2023-06-21

1591 EquiScore: A generic protein-ligand interaction scoring method integrating physical prior knowledge with data augmentation modeling

Cao, D.; Chen, G.; Jiang, J.; Yu, J.; Zhang, R.; Chen, M.; Zhang, W.; Chen, L.; Zhong, F.; Zhang, Y.; Lu, C.; Li, X.; Luo, X.; Zhang, S.; Zheng, M.

10.1101/2023.06.18.545464 — bioinformatics — Posted on 2023-06-21

1592 Cofea: correlation-based feature selection for single-cell chromatin accessibility data

Li, K.; Chen, X.; Song, S.; Hou, L.; Chen, S.; Jiang, R.

10.1101/2023.06.18.545397 — bioinformatics — Posted on 2023-06-21

1593 Development and Optimisation of in vitro Sonodynamic Therapy for Glioblastoma

Keenylside, A.; Marples, T.; Gao, Z.; Hu, H.; Nicely, L. G.; Nogales, J.; Li, H.; Landgraf, L.; Solth, A.; Melzer, A.; Hossain-Ibrahim, K.; Huang, Z.; Banerjee, S.; Joseph, J.

10.1101/2023.06.19.545530 — bioengineering — Posted on 2023-06-21

1594 Genetic Association of PLAG1 Gene Variant 14:25015640G>T with Wither-Height in Pakistani Cattle

Naeem, M.; Zahid, S.; Fatima, S.; Raza, M. H.; Zafar, M. O.; Saif, R.

10.1101/2023.06.18.545456 — genetics — Posted on 2023-06-21

1595 InsectChange: Comment

Gaume, L.; Desquilbet, M.

10.1101/2023.06.17.545310 — ecology — Posted on 2023-06-21

1596 PI3K/AKT signalling orchestrates ICM maturation and proper epiblast and primitive endoderm specification

Geiselmann, A.; Micouin, A.; Vandormael-Pournin, S.; Laville, V.; Mella, S.; Navarro, P.; Cohen-Tannoudji, M.

10.1101/2023.06.21.545867 — developmental biology — Posted on 2023-06-21

1597 Gradient boosted decision trees reveal nuances of auditory discrimination behaviour

Griffiths, C. S.; Lebert, J. M.; Sollini, J.; Bizley, J. K.

10.1101/2023.06.16.545302 — neuroscience — Posted on 2023-06-21

1598 KATP channel mutation disrupts hippocampal network activity and nocturnal γ shifts

Burkart, M.-E.; Kurzke, J.; Vera, J.; Ashcroft, F. M.; Eilers, J.; Lippmann, K.

10.1101/2023.06.18.545438 — neuroscience — Posted on 2023-06-21

1599 Physiological phenotypes differ among color morphs in introduced populations of the common wall lizard, Podarcis muralis

Amer, A.; Spears, S.; Vaughn, P. L.; Colwell, C.; Livingston, E. H.; McQueen, W.; Schill, A.; Reichard, D.; Gangloff, E. J.; Brock, K. M.

10.1101/2023.06.17.545449 — zoology — Posted on 2023-06-21

1600 Estimating Insulin Sensitivity and Beta-Cell Function from the Oral Glucose Tolerance Test: Validation of a new Insulin Sensitivity and Secretion (ISS) Model

Ha, J.; Chung, S. T.; Springer, M.; Kim, J. Y.; Chen, P.; Cree, M. G.; Behn, C. D.; Sumner, A. E.; Arslanian, S.; Sherman, A. S.

10.1101/2023.06.16.545377 — physiology — Posted on 2023-06-21

1601 Akt activator SC79 stimulates antibacterial nitric oxide production from human nasal epithelial cells and increases macrophage phagocytosis in vitro

Lee, R. J.; Adappa, N. D.; Palmer, J. N.

10.1101/2022.10.31.514559 — physiology — Posted on 2023-06-21

1602 A screening strategy based on two zebrafish eleuthero-embryo OECD test guidelines for the hazard assessment of chemicals: case of some bisphenol substitutes

Christophe, A.; Piccini, B.; Hinfray, N.; Chadili, E.; Maillot-Marechal, E.; cousin, x.; Blanc, M.; Charlier, T.; Pandard, P.; Ait-Aissa, S.; Brion, F.

10.1101/2023.06.16.545329 — pharmacology and toxicology — Posted on 2023-06-21

1603 Characterization of cannabinoid plasma concentration, maternal health, and cytokine levels in a rat model of prenatal Cannabis smoke exposure

Black, T.; Baccetto, S. L.; Barnard, I. L.; Finch, E.; McElroy, D. L.; Austin-Scott, F. V.; Greba, Q.; Michel, D.; Zagzoog, A.; Howland, J. G.; Laprairie, R. B.

10.1101/2023.06.16.545309 — pharmacology and toxicology — Posted on 2023-06-21

1604 Spatial and Temporal Analysis of SARS-CoV-2 Genome Evolutionary Patterns

Gupta, S.; Gupta, D.; Bhatnagar, S.

10.1101/2023.06.21.545910 — bioinformatics — Posted on 2023-06-21

1605 TopoDoE: A Design of Experiment strategy for selection and refinement in ensembles of executable Gene Regulatory Networks

Bouvier, M.; Zreika, S.; Vallin, E.; Fourneaux, C.; Gonin-Giraud, S.; Bonnaffoux, A.; Gandrillon, O.

10.1101/2023.04.21.537619 — bioinformatics — Posted on 2023-06-21

1606 Does the seed fall far from the tree? - weak fine scale genetic structure in a continuous Scots pine population

Niskanen, A. K.; Kujala, S. T.; Karkkainen, K.; Savolainen, O.; Pyhajarvi, T.

10.1101/2023.06.16.545344 — evolutionary biology — Posted on 2023-06-21

1607 Unexpectedly high coral heat tolerance at thermal refugia

Lachs, L.; Humanes, A.; Mumby, P. J.; Donner, S. D.; Bythell, J. C.; Beauchamp, E.; Bukurou, L.; Buzzoni, D.; de la Torre Cerro, R.; East, H. K.; Edwards, A. J.; Golbuu, Y.; Martinez, H. M.; van der Steeg, E.; Ward, A.; Guest, J. R.

10.1101/2023.06.16.545328 — ecology — Posted on 2023-06-21

1608 Aryl hydrocarbon receptor (AHR) and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis

Proper, S. P.; Dwyer, A. T.; Appiagyei, A.; Felton, J. M.; Ben-Baruch Morgenstern, N.; Marlman, J. M.; Kotliar, M.; Barski, A.; Troutman, T. D.; Rothenberg, M. E.; Mersha, T. B.; Azouz, N. P.

10.1101/2023.06.17.545291 — immunology — Posted on 2023-06-21

1609 Reduced Thalamic Excitation to Motor Cortical Pyramidal Tract Neurons in a Mouse Model of Parkinsonism

Chen, L.; Daniels, S.; Dvorak, R.; Chu, H.-y.

10.1101/2022.09.24.509340 — neuroscience — Posted on 2023-06-21

1610 Single-deletion-mutant, third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency

Jin, L.; Sullivan, H. A.; Zhu, M.; Lea, N. E.; Lavin, T. K.; Fu, X.; Matsuyama, M.; Hou, Y.; Feng, G.; Wickersham, I. R.

10.1101/2022.02.23.481706 — neuroscience — Posted on 2023-06-21

1611 Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

Gui, Y.; Kim, Y.; Brenna, S.; Wilmes, M.; Zaghen, G.; Kuchenbecker-Poels, L.; Voss, H. L.; Gocke, A.; Schlueter, H.; Schweizer, M.; Altmeppen, H. C.; Magnus, T.; Levy, E.; Puig, B.

10.1101/2023.06.16.545303 — neuroscience — Posted on 2023-06-21

1612 Multiplex qPCR assays for detection of two imperiled anuran species, Anaxyrus californicus and Spea hammondii, from environmental DNA

Rodgers, T. W.; Lovich, R. E.; Walton, J. A.; Prince, D. J.; Gonzalez, B. R.; Shaffer, H. B.; Mock, K. E.

10.1101/2022.12.20.521282 — zoology — Posted on 2023-06-21

1613 Rare disease research workflow using multilayer networks elucidates the molecular determinants of severity in Congenital Myasthenic Syndromes

Nunez-Carpintero, I.; O'Connor, E.; Rigau, M.; Bosio, M.; Spendiff, S.; Azuma, Y.; Topf, A.; Thompson, R.; 't Hoen, P. A. C.; Chamova, T.; Tournev, I.; Guergueltcheva, V.; Laurie, S.; Beltran, S.; Capella-Gutierrez, S.; Cirillo, D.; Lochmuller, H.; Valencia, A.

10.1101/2023.01.19.524736 — bioinformatics — Posted on 2023-06-21

1614 Towards Computing Attributions for DimensionalityReduction Techniques

Scicluna, M. C.; Grenier, J.-C.; Poujol, R.; Lemieux, S.; Hussin, J.

10.1101/2023.05.12.540592 — bioinformatics — Posted on 2023-06-21

1615 MT-MAG: Accurate and interpretable machine learning for complete or partial taxonomic assignments of metagenome-assembled genomes

Li, W.; Kari, L.; Yu, Y.; Hug, L. A.

10.1101/2022.01.12.475159 — bioinformatics — Posted on 2023-06-21

1616 Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

Wang, Y.; Kanai, M.; Tan, T.; Kamariza, M.; Tsuo, K.; Yuan, K.; Zhou, W.; Okada, Y.; Huang, H.; Turley, P.; Atkinson, E. G.; Martin, A. R.

10.1101/2022.12.29.522270 — genomics — Posted on 2023-06-21

1617 A supermatrix phylogeny of the world's bees (Hymenoptera: Anthophila)

Henriquez-Piskulich, P.; Hugall, A. F.; Stuart-Fox, D.

10.1101/2023.06.16.545281 — evolutionary biology — Posted on 2023-06-21

1618 Studies on the Escherichia coli ExbD Transmembrane Domain, Residue L132, and an Inhibitory Cyclic Peptide.

Jana, B.; Kopp, D. R.; Xie, M.; Rao, H. V.; Postle, K.

10.1101/2022.09.26.509584 — molecular biology — Posted on 2023-06-21

1619 Comparison of enrichment methods for efficient nitrogen fixation on a biocathode

Rous, A.; Santa-Catalina, G.; Le Quemener, E.; Trably, E.; Bernet, N.

10.1101/2023.03.02.530809 — microbiology — Posted on 2023-06-21

1620 Translation-dependent downregulation of Cas12a mRNA by an anti-CRISPR protein

Marino, N. D.; Talaie, A.; Carion, H.; Johnson, M. C.; Zhang, Y.; Silas, S.; Li, Y.; Bondy-Denomy, J.

10.1101/2022.11.29.518452 — microbiology — Posted on 2023-06-21

1621 Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in severe COVID-19

Sasaki, M.; Iida, S.; Hirata, Y.; Kusakabe, S.; Konishi, K.; Itakura, Y.; Tabata, K.; Kishimoto, M.; Kobayashi, H.; Ariizumi, T.; Intaruck, K.; Nobori, H.; Toba, S.; Sato, A.; Matsuno, K.; Yamagishi, J.; Suzuki, T.; Hall, W. W.; Orba, Y.; Sawa, H.

10.1101/2023.06.20.545832 — microbiology — Posted on 2023-06-21

1622 Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers

Krasik, S. V.; Bryushkova, E. A.; Sharonov, G. V.; Myalik, D. S.; Shurganova, E. V.; Komarov, D. V.; Shagina, I. A.; Shpudeiko, P. S.; Turchaninova, M. A.; Vakhitova, M. T.; Samoylenko, I. V.; Marinov, D. T.; Demidov, L. V.; Zagainov, V. E.; Chudakov, D. M.; Serebrovskaya, E. O.

10.1101/2023.04.16.537028 — immunology — Posted on 2023-06-21

1623 Large Scale Foundation Model on Single-cell Transcriptomics

Hao, M.; Gong, J.; Zeng, X.; Liu, C.; Guo, Y.; Cheng, X.; Wang, T.; Ma, J.; Song, L.; Zhang, X.

10.1101/2023.05.29.542705 — bioinformatics — Posted on 2023-06-21

1624 Phenotypic link between protein efficiency and pig welfare suggests no apparent trade-offs for mitigating nitrogen pollution

Roch, L.; Ewaoluwagbemiga, E. O.; Kasper, C.

10.1101/2023.03.03.530955 — animal behavior and cognition — Posted on 2023-06-21

1625 Hybrid machine-learning framework for volumetric segmentation and quantification of vacuoles in individual unlabeled yeast cells using holotomography

lee, m.; kunzi, m.; NEUROHR, G.; lee, s. s.; Park, Y.

10.1101/2023.06.18.545499 — biophysics — Posted on 2023-06-21

1626 Dating the bacterial tree of life with ancient symbiosis

Wang, S.; Luo, H.

10.1101/2023.06.18.545440 — evolutionary biology — Posted on 2023-06-21

1627 Task-evoked pulse wave amplitude tracks cognitive load

Pavlov, Y. G.; Gashkova, A. S.; Kasanov, D.; Kosachenko, A. I.; Kotyusov, A. I.; Kotchoubey, B.

10.1101/2023.06.16.545290 — neuroscience — Posted on 2023-06-21

1628 (Micro)saccade-related potentials during face recognition: A study combining EEG, eye-tracking, and deconvolution modeling

Spiering, L.; Dimigen, O.

10.1101/2023.06.16.545272 — neuroscience — Posted on 2023-06-21

1629 Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasite developmental stage differs between behaviors

Rigaud, T.; Balourdet, A.; Bauer, A.

10.1101/2023.04.25.538244 — zoology — Posted on 2023-06-21

1630 Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging

Poudel, S. B.; Benayed, D. F.; Ruff, R. R.; Yildirim, G.; Dixit, M.; Schaffler, M. B.; Korstanje, R.; Robinson, L.; Miller, R. A.; Harrison, D.; Strong, R.; Yakar, S.

10.1101/2023.06.16.545146 — pharmacology and toxicology — Posted on 2023-06-21

1631 Deep intravital brain tumor imaging enabled by tailored three-photon microscopy and analysis

Schubert, M. C.; Soyka, S. J.; Tamimi, A.; Maus, E.; Denninger, R.; Wissmann, N.; Reyhan, E.; Tetzlaff, S. K.; Beretta, C.; Drumm, M.; Schroers, J.; Steffens, A.; Walshon, J.; McCortney, K.; Heiland, S.; Golebiewska, A.; Kurz, F. T.; Wick, W.; Winkler, F.; Kreshuk, A.; Kuner, T.; Horbinski, C.; Prevedel, R.; Venkataramani, V.

10.1101/2023.06.17.545350 — cancer biology — Posted on 2023-06-21

1632 New distance measure for comparing protein using cellular automata image

Ferreira de Souza, L.; B. de B. Pereira, H.; M. da Rocha Filho, T.; A. S. Machado, B.; A. Moret, M.

10.1101/2023.06.16.545334 — bioinformatics — Posted on 2023-06-21

1633 Motoneuron-driven computational muscle modelling with motor unit resolution and subject-specific musculoskeletal anatomy

Caillet, A. H.; Phillips, A. T.; Farina, D.; Modenese, L.

10.1101/2023.06.03.543552 — bioengineering — Posted on 2023-06-21

1634 Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people inferred from 500 whole genome data from 39 populations

Sun, Y.; Wang, M.; Sun, Q.; Liu, Y.; Duan, S.; Wang, Z.; Zhou, Y.; Zhong, J.; Huang, Y.; Huang, X.; Li, X.; Su, H.; Cai, Y.; Jiang, X.; Chen, J.; Yan, J.; Nie, S.; Hu, L.; Yang, J.; Tang, R.; Wang, C.-C.; Liu, C.; Deng, X.; He, G.; Yun, L.

10.1101/2023.06.16.545243 — genetics — Posted on 2023-06-21

1635 Multityrosine Kinase Inhibitors Alleviate Laser-Induced Choroidal Neovascularization in Non-Human Primates: A Novel Therapy for Diabetic Retinopathy and Age-Related Macular Degeneration

Dell, S.; Nallakrishnan, R.; Horn, G.

10.1101/2023.06.20.545744 — molecular biology — Posted on 2023-06-20

1636 Discordance between different bioinformatic methods for identifying resistance genes from short-read genomic data, with a focus on Escherichia coli

Davies, T. J.; Swann, J.; Sheppard, A. E.; Pickford, H.; Lipworth, S.; AbuOun, M.; Ellington, M.; Fowler, P. W.; Hopkins, S.; Hopkins, K.; Crook, D.; Peto, T. E.; Anjum, M. F.; Walker, A. S.; Stoesser, N.

10.1101/2021.11.03.467004 — microbiology — Posted on 2023-06-21

1637 Microsaccades track location-based object rehearsal in visual working memory

de Vries, E.; van Ede, F.

10.1101/2023.03.21.533618 — neuroscience — Posted on 2023-06-21

1638 Selective plane activation structured illumination microscopy

Temma, K.; Oketani, R.; Kubo, T.; Bando, K.; Maeda, S.; Sugiura, K.; Matsuda, T.; Heintzmann, R.; Kaminishi, T.; Fukuda, K.; Hamasaki, M.; Nagai, T.; Fujita, K.

10.1101/2023.06.19.545558 — biophysics — Posted on 2023-06-21

1639 100 years of anthropogenic impact causes changes in freshwater functional biodiversity

Eastwood, N.; Zhou, J.; Derelle, R.; Abdallah, M. A.-E.; Stubbings, W. A.; Jia, Y.; Crawford, S. E.; Davidson, T. A.; Colbourne, J. K.; Creer, S.; Bik, H.; Hollert, H.; Orsini, L.

10.1101/2023.02.26.530075 — ecology — Posted on 2023-06-21

1640 Structure-guided design and optimization of covalent VHL-targeted sulfonyl fluoride PROTACs

Shah, R. R.; De Vita, E.; Conole, D.; Sathyamurthi, P. S.; Zhang, X.; Fellows, E.; Fleites, C. M.; Queisser, M. A.; Harling, J. D.; Tate, E. W.

10.1101/2023.06.20.545773 — molecular biology — Posted on 2023-06-20

1641 HTLV-1 Rex hijacks UPF1 in a CRM1 dependent manner, leading to NMD inhibition and revealing unexpected proviral roles of UPF1

Prochasson, L.; Mghezzi-Habellah, M.; Roisin, A.; Palma, M.; Robin, J.-P.; de Bossoreille, S.; Sareoua, L.; Cluet, D.; Mouehli, M.; Decimo, D.; Rety, S.; Desrames, A.; Chaze, T.; Matondo, M.; Dutartre, H.; Thoulouze, M.-I.; Lejeune, F.; Jalinot, P.; Mocquet, V.

10.1101/2023.06.20.545693 — molecular biology — Posted on 2023-06-20

1642 Analysis of DNA methylation in rainbow trout spermatozoa: the strengths and limitations of RRBS

El Kamouh, M.; Brionne, A.; Sayyari, A.; Lallias, D.; Labbe, C.; Laurent, A.

10.1101/2023.06.20.545730 — molecular biology — Posted on 2023-06-20

1643 Transcriptome Analysis Reveals Enhancement of Cardiogenesis-Related Signaling Pathways by S-nitroso-N-pivaloyl-D-penicillamine (SNPiP): Implications for Improved Diastolic Function and Cardiac Performance

Takenaka, Y.; Hirasaki, M.; Bono, H.; Nakamura, S.; Kakinuma, Y.

10.1101/2023.06.20.545771 — molecular biology — Posted on 2023-06-20

1644 Virome analysis of irrigation water sources provides extensive insights into the diversity and distribution of plant viruses in agroecosystems

Maksimovic, O.; Bacnik, K.; Selda Rivarez, M. P.; Vucurovic, A.; Mehle, N.; Ravnikar, M.; Gutierrez Aguirre, I.; Kutnjak, D.

10.1101/2023.06.20.545696 — molecular biology — Posted on 2023-06-20

1645 GRAS1 non-coding RNA protects against DNA damage and cell death by binding NKAP

Su, T.; Kong, L.; Cheung, D.; Zhu, J.; Chou, V. W.-H.; Camden, N.; Huang, C.; McHugh, C. A.

10.1101/2023.06.20.545783 — molecular biology — Posted on 2023-06-20

1646 N-terminal targeting sequences and coding sequences act in concert to determine the localization and trafficking pathway of apicoplast proteins in Toxoplasma gondii.

Anjum, S.; Prasad, A.; Mastud, P.; Patankar, S.

10.1101/2023.06.20.545694 — molecular biology — Posted on 2023-06-20

1647 An aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout for allogeneic CAR-T cells generation

Porreca, I.; Blassberg, R.; Joubert, B.; Harbottle, J.; Mielczarek, O.; Stombaugh, J.; Hemphill, K.; Sumner, J.; Pazeraitis, D.; Touza, J. L.; Francesatto, M.; Selmi, T.; Collantes, J. C.; Strezoska, Z.; Taylor, B.; Jin, S.; Wiggins, C. M.; van Brabant Smith, A.; Lambourne, J. J.

10.1101/2023.06.20.545315 — molecular biology — Posted on 2023-06-21

1648 Warming affects routine swimming activity and novel odour molecular response in larval zebrafish

Sourisse, J. M.; Bonzi, L. C.; Semmelhack, J.; Schunter, C.

10.1101/2023.06.16.545285 — molecular biology — Posted on 2023-06-21

1649 Metagenomic survey of antimicrobial resistance (AMR) in Maryland surface waters differentiated by high and low human impact

Kocurek, B.; Martin, G.; Behling, S.; Ramachandran, P.; Reed, E.; Grim, C. J.; Mammel, M.; Zheng, J.; Franklin, A.; Garland, J.; Tadesse, D.; Sharma, M.; Tyson, G.; Kabera, C.; Tate, H.; McDermott, P. F.; Strain, E. A.; Ottesen, A.

10.1101/2023.06.20.545726 — microbiology — Posted on 2023-06-20

1650 Ultrastructural details of resistance factors of the bacterial spore revealed by in situ cryo-electron tomography

Bauda, E.; Gallet, B.; Moravcova, J.; Effantin, G.; Chan, H.; Novacek, J.; Jouneau, P.-H.; Rodrigues, C. D. A.; Schoehn, G.; Moriscot, C.; Morlot, C.

10.1101/2023.06.20.545718 — microbiology — Posted on 2023-06-20

1651 Machine learning classification by fitting amplicon sequences to existing OTUs

Armour, C. R.; Sovacool, K. L.; Close, W. L.; Topcuoglu, B. D.; Wiens, J.; Schloss, P. D.

10.1101/2022.09.01.506299 — microbiology — Posted on 2023-06-21

1652 Boosting of neural circuit chaos at the onset of collective oscillations

Palmigiano, A.; Engelken, R.; Wolf, F.

10.1101/2022.08.28.505598 — neuroscience — Posted on 2023-06-21

1653 Identifying and overcoming the sampling challenges in relative binding free energy calculations of a model protein:protein complex

Zhang, I.; Rufa, D. A.; Pulido, I.; Henry, M. M.; Rosen, L. E.; Hauser, K.; Singh, S.; Chodera, J. D.

10.1101/2023.03.07.530278 — biophysics — Posted on 2023-06-21

1654 Discovery of Potent Inhibitors of α-Synuclein Aggregation Using Structure-Based Iterative Learning

Horne, R. I.; Andrzejewska, E.; Alam, P.; Brotzakis, Z. F.; Srivastava, A.; Aubert, A.; Nowinska, M.; Gregory, R. C.; Staats, R.; Possenti, A.; Chia, S.; Sormanni, P.; Ghetti, B.; Caughey, B.; Knowles, T. P. J.; Vendruscolo, M.

10.1101/2021.11.10.468009 — biophysics — Posted on 2023-06-21

1655 Causal Effects of Pupil Size on Visual Processing

Mathot, S.; Berberyan, H.; Buchel, P.; Ruuskanen, V.; Vilotijevic, A.; Kruijne, W.

10.1101/2023.03.08.531702 — animal behavior and cognition — Posted on 2023-06-21

1656 Nucleus-Independent Transgenerational Small RNA Inheritance in C. elegans

Rieger, I.; Weintraub, G.; Lev, I.; Goldstein, K.; Bar-Zvi, D.; Anava, S.; Gingold, H.; Shaham, S.; Rechavi, O.

10.1101/2023.06.20.545749 — genetics — Posted on 2023-06-21

1657 Stepwise evolution of E. coli C and {varphi}X174 reveals unexpected lipopolysaccharide (LPS) diversity

Romeyer Dherbey, J.; Parab, L.; Gallie, J.; Bertels, F.

10.1101/2022.09.06.506728 — evolutionary biology — Posted on 2023-06-21

1658 A step towards measuring connectivity in the deep-sea: elemental fingerprints of mollusk larval shells discriminate hydrothermal sites

Mouchi, V.; Pecheyran, C.; Claverie, F.; Cathalot, C.; Matabos, M.; Germain, Y.; Rouxel, O.; Jollivet, D.; Broquet, T.; Comtet, T.

10.1101/2023.01.03.522618 — ecology — Posted on 2023-06-21

1659 Acute targeted induction of gut-microbial metabolism disrupts host circadian rhythm

Greter, G.; Oswald, S.; Kuenzli, D.; Lan, J.; Slack, E.; Arnoldini, M.

10.1101/2023.06.20.545777 — microbiology — Posted on 2023-06-20

1660 Novel hydrogen- and iron-oxidizing sheath-producing Zetaproteobacteria thrive at the Favne deep-sea hydrothermal vent field

Hribovsek, P.; Olesin Denny, E.; Dahle, H.; Mall, A.; Ofstegaard Viflot, T.; Boonnawa, C.; Reeves, E. E.; Steen, I. H.; Stokke, R.

10.1101/2023.06.20.545787 — microbiology — Posted on 2023-06-21

1661 Oxidative Stress is Intrinsic to Staphylococcal Adaptation to Fatty Acid Synthesis Antibiotics

Wongdontree, P.; Millan-Oropeza, A.; Upfold, J.; Lavergne, J.-P.; Halpern, D.; Lambert, C.; Page, A.; Kenanian, G.; Grangeasse, C.; Henry, C.; Fouet, A.; Gloux, K.; Anba-Mondoloni, J.; Gruss, A.

10.1101/2022.09.09.506511 — microbiology — Posted on 2023-06-21

1662 Few temporally distributed brain connectivity states predict human cognitive abilities

Wehrheim, M. H.; Faskowitz, J.; Sporns, O.; Fiebach, C.; Kaschube, M.; Hilger, K.

10.1101/2022.12.23.521743 — neuroscience — Posted on 2023-06-21

1663 Body size shapes song in honeyeaters

Hay, E. M.; McGee, M. D.; White, C. R.; Chown, S. L.

10.1101/2023.06.20.545811 — evolutionary biology — Posted on 2023-06-21

1664 The Cystic Fibrosis treatment, Trikafta, affects growth, viability, and cell wall of Aspergillus fumigatus biofilms

Jones, J. T.; Morelli, K. A.; Vesely, E. M.; Puerner, C.; Pavuluri, C.; Ross, B. S.; Rhijn, N. v.; Bromley, M. J.; Cramer, R. A.

10.1101/2023.06.20.545692 — microbiology — Posted on 2023-06-21

1665 Kir2.1 modulation in macrophages sensitises dorsal root ganglion neurons through TNF secretion after nerve injury

Konnova, E. A.; Deftu, A.-F.; Chu Sin Chung, P.; Kirschmann, G.; Decosterd, I.; Suter, M. R.

10.1101/2023.06.21.545843 — neuroscience — Posted on 2023-06-21

1666 The MODY-associated TALK-1 L114P mutation causes islet α-cell overactivity and β-cell inactivity resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

Nakhe, A. Y.; Dadi, P. K.; Kim, J.; Shrestha, S.; Cartailler, J.-P.; Sampson, L.; Magnuson, M. A.; Jacobson, D. A.

10.1101/2023.06.20.545631 — physiology — Posted on 2023-06-21

1667 Divergence of TORC1-mediated Stress Response Leads to Novel Acquired Stress Resistance in a Pathogenic Yeast

Liang, J.; Youngstrom, C. E.; He, B. Z.

10.1101/2023.06.20.545716 — microbiology — Posted on 2023-06-20

1668 Hypogonadal (Gnrh1hpg) mice reveal niche-specific influence of reproductive axis and sex on intestinal microbial communities

Sisk-Hackworth, L.; Brown, J.; Sau, L.; Levine, A. A.; Tam, L. Y. I.; Ramesh, A.; Shah, R. S.; Kelley-Thackray, E. T.; Wang, S.; Nguyen, A.; Kelley, S. T.; Thackray, V. G.

10.1101/2023.06.20.545808 — microbiology — Posted on 2023-06-20

1669 A new multiplex TaqMan qPCR targeting Clavibacter michiganensis virulence-related genes

Brochu, A.-S.; Dumonceaux, T.; Belanger, R.; Perez-Lopez, E.

10.1101/2023.06.20.545733 — microbiology — Posted on 2023-06-20

1670 Single Cell Transcriptomics Reveals the Hidden Microbiomes of Human Tissues

mahmoudabadi, G.; Crasta, S.; Tabula Sapiens Consortium, ; Quake, S.

10.1101/2022.10.11.511790 — microbiology — Posted on 2023-06-20

1671 Mutational analysis of LtgC, a lytic transglycosylase required for cell separation in Neisseria gonorrhoeae

Schaub, R. E.; Perez-Medina, K. M.; Tomberg, J.; Nicholas, R. A.; Dillard, J. P.

10.1101/2023.06.20.545760 — microbiology — Posted on 2023-06-20

1672 Identification of a novel HKU4-related coronavirus in single-cell datasets and clade viral host analysis

Jones, A.; Massey, S. E.; Nemzer, L. R.; Zhang, D.; Deigin, Y.; Quay, S. C.

10.1101/2023.06.18.545480 — genomics — Posted on 2023-06-21

1673 Pan-genome analysis of six complete Paracoccus type strain genomes from hybrid next generation sequencing

Hollensteiner, J.; Schneider, D.; Poehlein, A.; Brinkhoff, T. H.; Daniel, R.

10.1101/2023.06.19.545646 — microbiology — Posted on 2023-06-20

1674 A neuro-intestinal circuit controls mitochondrial dynamics and stress resistance

Cornell, R.; Cao, W.; Harradine, B.; Handley, A.; Pocock, R.

10.1101/2023.06.19.545634 — neuroscience — Posted on 2023-06-21

1675 Frequent asymmetric migrations suppress natural selection in spatially structured populations

Abbara, A.; Bitbol, A.-F.

10.1101/2023.06.19.545559 — biophysics — Posted on 2023-06-21

1676 miR-252 targeting temperature receptor CcTRPM to mediate the transition from summer-form to winter-form of Cacopsylla chinensis

Zhang, S.; Li, J.; Zhang, D.; Zhang, Z.; Meng, S.; Li, Z.; Liu, X.

10.1101/2023.06.16.545283 — evolutionary biology — Posted on 2023-06-20

1677 Effect of a retinoic acid analogue on BMP-driven pluripotent stem cell chondrogenesis

Mancini, F. E.; Humphreys, P. E. A.; Woods, S.; Bates, N.; Cuvertino, S.; O'Flaherty, J.; Biant, L.; Domingos, M. A. N.; Kimber, S. J.

10.1101/2023.06.20.545738 — developmental biology — Posted on 2023-06-21

1678 Sexual dimorphism in the social behaviour of Cntnap2 KO mice correlates with disrupted synaptic connectivity and increased microglial activity in the anterior cingulate cortex of males

Dawson, M. S.; Gordon-Fleet, K.; Yan, L. J.; Tardos, V.; He, H.; Mui, K.; Nawani, S.; Asgarian, Z.; Catani, M.; Fernandes, C.; Drescher, U.

10.1101/2023.06.20.545580 — neuroscience — Posted on 2023-06-21

1679 Representational drift as a result of implicit regularization

Ratzon, A.; Derdikman, D.; Barak, O.

10.1101/2023.05.04.539512 — neuroscience — Posted on 2023-06-21

1680 Jointly efficient encoding and decoding in neural populations

Blanco Malerba, S.; Micheli, A.; Woodford, M.; Azeredo da Silveira, R.

10.1101/2023.06.21.545848 — neuroscience — Posted on 2023-06-21

1681 Larger and denser: an optimal design for surface grids of EMG electrodes to identify greater and more representative samples of motor units

Caillet, A. H.; Avrillon, S.; Kundu, A.; Yu, T.; Phillips, A. T. M.; Modenese, L.; Farina, D.

10.1101/2023.02.18.529050 — neuroscience — Posted on 2023-06-21

1682 genomicBERT and data-free deep-learning model evaluation

Chen, T.; Tyagi, N.; Chauhan, S.; Peleg, A. Y.; Tyagi, S.

10.1101/2023.05.31.542682 — bioinformatics — Posted on 2023-06-21

1683 Efficient estimation for large-scale linkage disequilibrium patterns of the human genome

Huang, X.; Zhu, T.-N.; Liu, Y.-C.; Zhang, J.-N.; Chen, G.-B.

10.1101/2023.06.18.545475 — evolutionary biology — Posted on 2023-06-20

1684 The extension of mammalian pregnancy required taming inflammation; independent evolution of extended placentation in the tammar wallaby

Dudley, J. S.; Renfree, M. B.; Wagner, G. P.; Griffith, O. W.

10.1101/2023.06.18.545206 — evolutionary biology — Posted on 2023-06-21

1685 Determination of Accumulation of Molecules in Escherichia coli

Ongwae, G. M.; Liu, Z.; Chorida, M. D.; Guo, T.; Dong, J.; Pires, M.

10.1101/2023.06.20.545103 — microbiology — Posted on 2023-06-20

1686 The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples

Vladimirov, N.; Voigt, F.; Naert, T.; Araujo, G. R.; Cai, R.; Reuss, A. M.; Zhao, S.; Schmid, P.; Hildebrand, S.; Schaettin, M.; Groos, D.; Mateos, J. M.; Bethge, P.; Yamamoto, T.; Aerne, V.; Roebroeck, A.; Ertürk, A.; Aguzzi, A.; Ziegler, U.; Stoeckli, E. T.; Baudis, L.; Lienkamp, S. S.; Helmchen, F.

10.1101/2023.06.16.545256 — neuroscience — Posted on 2023-06-21

1687 Endogenous oscillatory rhythms and interactive contingencies jointly influence infant attention during early infant-caregiver interaction

Phillips, E. A. M.; Goupil, L.; Csolsim, F.; Whitehorn, M.; Kaur, N.; Bruce-Gardyne, E.; Greenwood, E.; Marriott-Haresign, I.; Wass, S.

10.1101/2023.06.19.545295 — neuroscience — Posted on 2023-06-21

1688 Metabolic intervention by low carbohydrate diet suppresses the onset and progression of neuroendocrine tumor

Chen, Y.; Yamamoto, T.; Takahashi, Y.; Moro, T.; Tajima, T.; Sakaguchi, Y.; Sakata, N.; Yokoyama, A.; Hijioka, S.; Sada, A.; Tabata, Y.; Ohki, R.

10.1101/2022.10.21.507065 — cancer biology — Posted on 2023-06-21

1689 PICKLUSTER: A protein-interface clustering and analysis plug-in for UCSF ChimeraX

Genz, L. R.; Mulvaney, T.; Nair, S.; Topf, M.

10.1101/2023.06.19.545106 — bioinformatics — Posted on 2023-06-21

1690 Levy statistics define anxiety and depression in mice subjected to chronic stress

Li, Q.; Nie, Y.; Zhang, Y.; Xia, M.; Zhao, B.; Tian, C.; Lai, Q.; Luo, Y.; Chen, D.; Zhang, N.; Kuang, W.; He, Y.; Li, X.; Mei, C.; Zhang, T.; Wu, Z.; Zhong, Z.

10.1101/2023.06.18.545232 — animal behavior and cognition — Posted on 2023-06-21

1691 Influenza A genomic diversity during human infections underscores the strength of genetic drift and the existence of tight transmission bottlenecks

Martin, M. A.; Berg, N.; Koelle, K.

10.1101/2023.06.18.545481 — evolutionary biology — Posted on 2023-06-21

1692 A Likelihood Ratio Test for Hybridization Under the Multispecies Coalescent

Peng, J.; Kong, S.; Kubatko, L.

10.1101/2023.06.20.545699 — evolutionary biology — Posted on 2023-06-21

1693 Defining the impact of flavivirus envelope protein glycosylation on sensitivity to broadly neutralizing antibodies

Contreras, M.; Stuart, J. B.; Levoir, L. M.; Belmont, L.; Goo, L.

10.1101/2023.06.20.545776 — microbiology — Posted on 2023-06-20

1694 Defining the impact of flavivirus envelope protein glycosylation on sensitivity to broadly neutralizing antibodies

Contreras, M.; Stuart, J. B.; Levoir, L. M.; Belmont, L.; Goo, L.

10.1101/2023.06.20.545776 — microbiology — Posted on 2023-06-21

1695 A transthalamic pathway crucial for perception

Mo, C.; McKinnon, C.; Makitani, M.; Sherman, S. M.

10.1101/2023.03.30.533323 — neuroscience — Posted on 2023-06-21

1696 Eye Blinks as a Visual Processing Stage

Yang, B.; Intoy, J.; Rucci, M.

10.1101/2023.06.18.545489 — neuroscience — Posted on 2023-06-21

1697 Cross-species single-cell annotation with orthologous marker gene groups

Chau, T.; Timilsena, P. R.; Bathala, S. P.; Bargmann, B.; Li, S.

10.1101/2023.06.18.545471 — bioinformatics — Posted on 2023-06-20

1698 Assessing the performance of protein regression models

Michael, R.; Kaestel-Hansen, J.; Groth, P. M.; Bartels, S.; Salomon, J.; Tian, P.; Hatzakis, N. S.; Boomsma, W.

10.1101/2023.06.18.545472 — bioinformatics — Posted on 2023-06-21

1699 From asexuality to sexual reproduction: cyclical switch of gametogenic pathways in hybrids depend on ploidy level

Dedukh, D.; Marta, A.; Myung, R.-Y.; Ko, M.-H.; Choi, D.-S.; Won, Y.-J.; Janko, K.

10.1101/2023.06.18.545483 — evolutionary biology — Posted on 2023-06-21

1700 Chemodiversity in flowers of Tanacetum vulgare has consequences on a florivorous beetle

Sasidharan, R.; Brokate, L.; Eilers, E. J.; Mueller, C.

10.1101/2023.06.19.545548 — ecology — Posted on 2023-06-21

1701 Cell arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms

Dayton, H.; Kiss, J.; Wei, M.; Chauhan, S.; LaMarre, E.; Cornell, W. C.; Janakiraman, A.; Min, W.; Tomer, R.; Price-Whelan, A.; Nirody, J. A.; Dietrich, L. E.

10.1101/2023.06.20.545666 — microbiology — Posted on 2023-06-20

1702 Wireless monitoring of respiration with EEG reveals relationships between respiration, behaviour and brain activity in freely moving mice

Dasgupta, D.; Schneider-Luftman, D.; Schaefer, A.; Harris, J. J.

10.1101/2023.06.19.544346 — neuroscience — Posted on 2023-06-21

1703 Integrating Image and Molecular Profiles for Spatial Transcriptomics Analysis

Jiang, X.; Wang, S.; Guo, L.; Wen, Z.; Jia, L.; Xu, L.; Xiao, G.; Li, Q.

10.1101/2023.06.18.545488 — bioinformatics — Posted on 2023-06-20

1704 Chemical inhibition of histidine biosynthesis curtails M. tuberculosis infection

Tiwari, S.; Ahmad, M.; Kumar, V.; Kar, D.; Kumari, S.; Dwivedy, A.; Pal, R. K.; MOHAPATRA, A. K.; Nain, V. K.; Barik, V.; Pal, R.; Nanda, R. K.; Pandey, A. K.; Biswal, B.

10.1101/2023.06.20.545697 — biochemistry — Posted on 2023-06-20

1705 Virome analysis of New Zealand's bats reveals cross-species viral transmission among the Coronaviridae

Waller, S. J.; Tortosa, P.; Thurley, T.; O'Donnell, C.; Jackson, R.; Dennis, G.; Grimwood, R. M.; Holmes, E. C.; McInnes, K.; Geoghegan, J. L.

10.1101/2023.06.19.545647 — microbiology — Posted on 2023-06-20

1706 Cyanide-dependent control of terminal oxidase hybridization by Pseudomonas aeruginosa MpaR

Smiley, M.; Sekaran, D.; Price-Whelan, A.; Dietrich, L. E. P.

10.1101/2023.05.31.543164 — microbiology — Posted on 2023-06-20

1707 Blockade of IKK signaling induces RIPK1-independent apoptosis in human cells

Nataraj, N. M.; Herrmann, B.; Shin, S.; Brodsky, I. E.

10.1101/2023.06.20.545781 — immunology — Posted on 2023-06-20

1708 Characterizing Adeno-Associated Virus Capsids with both Denaturing and Intact Analysis Methods

Ryan, J. P.; Kostelic, M. M.; Hsieh, C.-C.; Powers, J. B.; Aspinwall, C. A.; Dodds, J. N.; Schiel, J. E.; Marty, M. T.; Baker, E. S.

10.1101/2023.06.20.543103 — biochemistry — Posted on 2023-06-20

1709 Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site

Bimai, O.; Banerjee, I.; Grinberg, I. R.; Huang, P.; Lundin, D.; Sjöberg, B.-M.; Logan, D. T.

10.1101/2023.06.20.545753 — biochemistry — Posted on 2023-06-20

1710 Tissue-adjusted pathway analysis of cancer (TPAC)

Frost, H. R.

10.1101/2022.03.17.484779 — genomics — Posted on 2023-06-20

1711 Resistance towards and biotransformation of Pseudomonas-produced secondary metabolites during community invasion

Hansen, M. L.; Denes, Z.; Jarmusch, S. A.; Wibowo, M.; Lozano-Andrade, C. N.; Kovacs, A. T.; Strube, M. L.; Andersen, A. J. C.; Jelsbak, L.

10.1101/2023.06.20.545698 — microbiology — Posted on 2023-06-20

1712 Opposing chemosensory functions of closely related gustatory receptors

Ahn, J.-E.; Amrein, H.

10.1101/2023.06.20.545761 — neuroscience — Posted on 2023-06-20

1713 Target-decoy false discovery rate estimation using Crema

Lin, A.; See, D.; Keich, U.; Fondrie, W. E.; Noble, W. S.

10.1101/2023.06.18.545038 — bioinformatics — Posted on 2023-06-20

1714 Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking

Chio, U. S.; Palovcak, E.; Autzen, A. A. A.; Autzen, H. E.; Munoz, E. N.; Yu, Z.; Wang, F.; Agard, D. A.; Armache, J.-P.; Narlikar, G.; Cheng, Y.

10.1101/2023.06.20.545796 — biochemistry — Posted on 2023-06-20

1715 On the origin and evolution of the mosquito male-determining factor Nix

Biedler, J. K.; Aryan, A.; Qi, Y.; Wang, A.; Martinson, E. O.; Hartman, D.; Yang, F.; Sharma, A.; Morton, K.; Potters, M.; Chen, C.; Dobson, S. L.; Ebel, G.; Kading, R. C.; Paulson, S.; Xue, R.-D.; Strand, M. R.; Tu, Z.

10.1101/2022.12.07.519398 — evolutionary biology — Posted on 2023-06-20

1716 Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons

Liu, W.; Shrestha, R.; Lowe, A.; Zhang, X.; Spaeth, L.

10.1101/2023.03.22.533827 — developmental biology — Posted on 2023-06-20

1717 Drug Resistance without a cost? Common and uncommon routes to fosfomycin resistance in Uropathogenic Escherichia coli

Bermudez, T.; Brannon, J. R.; Dudipala, N.; Reasoner, S.; Morales, G. H.; Wiebe, M. A.; Cecala, M.; Beebout, C. J.; Amir, O.; Hadjifrangiskou, M.

10.1101/2023.06.20.545750 — microbiology — Posted on 2023-06-20

1718 Automating clinical assessments of memory deficits: Deep Learning based scoring of the Rey-Osterrieth Complex Figure

Langer, N.; Weber, M.; Hebling Vieira, B.; Strzelczyk, D.; Wolf, L.; Pedroni, A.; Heitz, J.; Schultheis, C.; Troendle, M.; Arango Lasprilla, J. C.; Rivera, D.; Scarpina, F.; Zhao, Q.; Leuthold, R.; Wehrle, F.; Jenni, O. G.; Brugger, P.; Zaehle, T.; Lorenz, R.; Zhang, C.

10.1101/2022.06.15.496291 — neuroscience — Posted on 2023-06-20

1719 Direct observation of the neural computations underlying a single decision

Steinemann, N. A.; Stine, G. M.; Trautmann, E. M.; Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.

10.1101/2022.05.02.490321 — neuroscience — Posted on 2023-06-20

1720 Readiness to retrieve memories of different ages: An ERP dissociation of orienting and difficulty

Leiker, E. K.; Johnson, J. D.

10.1101/2022.07.25.501431 — neuroscience — Posted on 2023-06-20

1721 Single-neuron and population measures of neuronal activity in working memory tasks

Mozumder, R.; Constantinidis, C.

10.1101/2023.06.18.545508 — neuroscience — Posted on 2023-06-20

1722 PDF neuropeptide signals independently of Bruchpilot-labelled active zones in daily remodelled terminals of Drosophila clock neurons

Hofbauer, B.; Zandawala, M.; Reinhard, N.; Rieger, D.; Werner, C.; Evers, J.-F.; Wegener, C.

10.1101/2023.06.20.545701 — neuroscience — Posted on 2023-06-20

1723 CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma

Cho, M. M.; Song, L.; Quamine, A. E.; Szewc, F.; Shi, L.; Erbe, A. K.; Ebben, J. D.; Turicek, D. P.; Kline, J. M.; Lafeber, E. O.; Phillips, M. F.; Ceas, A. S.; Capitini, C. M.

10.1101/2023.06.07.544144 — cancer biology — Posted on 2023-06-20

1724 Designing meaningful continuous representations of T cell receptor sequences with deep generative models

Leary, A. Y.; Scott, D.; Gupta, N. T.; Waite, J. C.; Skokos, D.; Atwal, G. S.; Hawkins, P. G.

10.1101/2023.06.17.545423 — bioinformatics — Posted on 2023-06-20

1725 The impact of similarity metrics on cell type clustering in highly multiplexed in situ imaging cytometry data

Willie, E.; Yang, P.; Patrick, E.

10.1101/2023.01.18.524659 — bioinformatics — Posted on 2023-06-20

1726 Zoledronate reduces loading-induced microdamage in cortical ulna of ovariectomized rats

Ning, B.; Londono, I.; Laporte, C.; Villemure, I.

10.1101/2023.05.12.540579 — bioengineering — Posted on 2023-06-20

1727 Magnetogenetic cell activation using endogenous ferritin

Stanley, S. A.; Pomeranz, L. E.; Li, R.; Yu, X. A.; Kelly, L.; Hassanzadeh, G.; Molina, H.; Gross, D.; Brier, M. I.; Vaisey, G.; Jimenez-Gonzalez, M.; Garcia-Ocana, A.; Dordick, J.; Friedman, J. M.

10.1101/2023.06.20.545120 — bioengineering — Posted on 2023-06-20

1728 The membrane-cytoplasmic linker defines activity of FtsH proteases

Mawla, G. D.; Kamal, S. M.; Cao, L.; Purhonen, P.; Hebert, H.; Sauer, R. T.; Baker, T. A.; Romling, U.

10.1101/2023.06.19.545564 — biochemistry — Posted on 2023-06-20

1729 Pollen contamination and mating structure in maritime pine (Pinus pinaster Ait.) clonal seed orchards revealed by SNP markers

Bouffier, L.; Debille, S.; Alazard, P.; Raffin, A.; Pastuszka, P.; Trontin, J.-F.

10.1101/2022.09.27.509769 — genetics — Posted on 2023-06-20

1730 Shared evolutionary processes shape landscapes of genomic variation in the great apes

Rodrigues, M. F.; Kern, A. D.; Ralph, P. L.

10.1101/2023.02.07.527547 — evolutionary biology — Posted on 2023-06-20

1731 Diversity at single nucleotide to pangenome scales among sulfur cycling bacteria in salt marshes

Perez Castro, S.; Peredo, E. L.; Mason, O.; Vineis, J. H.; Bowen, J. L.; Mortazavi, B.; Ganesh, A.; Ruff, S. E.; Paul, B. G.; Giblin, A.; Cardon, Z.

10.1101/2023.06.08.544202 — ecology — Posted on 2023-06-20

1732 Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation

Dikiy, S.; Levine, A. G.; Giovanelli, P.; Wang, Z.-M.; Beroshvili, G.; Pritykin, Y.; Krishna, C.; Glasner, A.; Leslie, C. S.; Rudensky, A. Y.

10.1101/2022.05.16.492030 — immunology — Posted on 2023-06-20

1733 Hypocretin/orexin neurons encode social discrimination and exhibit a sex-dependent necessity for social interaction

Dawson, M.; Terstege, D. J.; Jamani, N.; Tsutsui, M.; Pavlov, D.; Bugescu, R.; Epp, J. R.; Leinninger, G. M.; Sargin, D.

10.1101/2022.08.19.504565 — neuroscience — Posted on 2023-06-20

1734 Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1

Smith, B. C.; Tinkey, R. A.; Mariam, A.; Habean, M. L.; Dutta, R.; Williams, J. L.

10.1101/2023.06.20.545679 — neuroscience — Posted on 2023-06-20

1735 A low dimensional manifold of human exploration and exploitation behavior reveals states of apathy and anxiety

Yan, X.; Ebitz, B.; Grissom, N.; Darrow, D.; Herman, A.

10.1101/2023.06.19.545645 — neuroscience — Posted on 2023-06-20

1736 DRomics, a workflow to exploit dose-response omics data in ecotoxicology

Delignette-Muller, M. L.; Billoir, E.; Siberchicot, A.; Larras, F.

10.1101/2023.02.09.527852 — bioinformatics — Posted on 2023-06-20

1737 Collective pooling of foraging information in animal fission-fusion dynamics

Ramos-Fernandez, G.; Smith Aguilar, S. E.

10.1101/2023.06.16.545019 — animal behavior and cognition — Posted on 2023-06-20

1738 ITPK1 regulates jasmonate-controlled root development in Arabidopsis thaliana

Laha, D.; Pullagurla, N. J.; Shome, S.; Yadav, R.

10.1101/2023.06.16.545325 — plant biology — Posted on 2023-06-20

1739 A marine bacterium elicits the type III secretion-dependent nonhost hypersensitive response in a land plant

Lee, B.; Lee, J.-I.; Kwon, S.-K.; Ryu, C.-M.; Kim, J. F.

10.1101/2023.06.20.545751 — plant biology — Posted on 2023-06-20

1740 Mapping the landscape of transcription factor promoter activity during vegetative development in Marchantia

Romani, F.; Sauret-Güeto, S.; Rebmann, M.; Annese, D.; Bonter, I.; Tomaselli, M.; Dierschke, T.; Delmans, M.; Frangedakis, E.; Silvestri, L.; Rever, J.; Bowman, J. L.; Romani, I.; Haseloff, J.

10.1101/2023.06.17.545419 — plant biology — Posted on 2023-06-20

1741 Oligosaccharide production and signaling correlate with delayed flowering in an Arabidopsis genotype grown and selected in high

Kinmonth-Schultz, H.; Walker, S. M.; Bingol, K.; Hoyt, D. W.; Kim, Y.-M.; Markillie, L. M.; Mitchell, H. D.; Nicora, C. D.; Taylor, R.; Ward, J. K.

10.1101/2023.06.19.545630 — plant biology — Posted on 2023-06-20

1742 Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair

Aube, F.; Fontrodona, N.; Guiguettaz, L.; Vallin, E.; Lapendry, A.; Ricci, E. P.; Auboeuf, D.

10.1101/2023.06.19.544800 — cancer biology — Posted on 2023-06-20

1743 Disposition and Toxicity of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure

Bullert, A.; Li, X.; Zhang, C.; Lee, K.; Pulliam, C. F.; Klingelhutz, A. J.; Robertson, L. W.; Lehmler, H.-J.

10.1101/2023.06.19.544952 — pharmacology and toxicology — Posted on 2023-06-20

1744 dingo: a Python package for metabolic flux sampling

Chalkis, A.; Fisikopoulos, V.; Tsigaridas, E.; Zafeiropoulos, H.

10.1101/2023.06.18.545486 — bioinformatics — Posted on 2023-06-20

1745 APOGEE 2: multi-layer machine-learning model for the interpretable prediction of mitochondrial missense variants

Bianco, S. D.; Parca, L.; Petrizzelli, F.; Biagini, T.; Giovannetti, A.; Liorni, N.; Napoli, A.; Carella, M.; Procaccio, V.; Lott, M.; Zhang, S.; Vescovi, A. L.; Wallace, D. C.; Caputo, V.; Mazza, T.

10.1101/2023.06.18.545476 — bioinformatics — Posted on 2023-06-20

1746 A supermatrix phylogeny of the world's bees (Hymenoptera: Anthophila)

Henriquez-Piskulich, P.; Hugall, A. F.; Stuart-Fox, D.

10.1101/2023.06.16.545281 — evolutionary biology — Posted on 2023-06-20

1747 Compensatory growth and recovery of tissue cytoarchitecture after transient cartilage-specific cell death in foetal mouse limbs

Hng, C. H.; Amarasinghe, S.; Zhang, B.; Chang, H.; Powell, D.; Rosello-Diez, A.

10.1101/2023.06.20.545035 — developmental biology — Posted on 2023-06-20

1748 Decreasing alpha flow releases task-specific processing paths

Hanna, J.; Kim, C.; Rampp, S.; Buchfelder, M.; Mueller-Voggel, N.

10.1101/2023.06.18.545474 — neuroscience — Posted on 2023-06-20

1749 Novel carbon nanoparticles derived from Bougainvillea modulate vegetative growth in Arabidopsis

Barot, R.; Gawande, N. D.; Omprabha, S.; Kaushal, C.; Saha, J.; Bhatia, D.; Sankaranarayanan, S.

10.1101/2023.06.19.545555 — plant biology — Posted on 2023-06-20

1750 Correlation between plant cell wall stiffening and root extension arrest phenotype in the combined abiotic stress of Fe and Al

Kaur, H.; Teulon, J.-M.; Godon, C.; Desnos, T.; Chen, S.-w. W.; Pellequer, J.-L.

10.1101/2023.06.20.545659 — plant biology — Posted on 2023-06-20

1751 Translation is a key determinant controlling the fate of cytoplasmic long non-coding RNAs

Andjus, S.; Szachnowski, U.; Vogt, N.; Hatin, I.; Cornu, D.; Papadopoulos, C.; Lopes, A.; Namy, O.; Wery, M.; Morillon, A.

10.1101/2022.05.25.493276 — molecular biology — Posted on 2023-06-20

1752 Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

De Cae, S.; Van Molle, I.; van Schie, L.; Shoemaker, S. R.; Deckers, J.; Debeuf, N.; Lameire, S.; Nerinckx, W.; Roose, K.; Fijalkowska, D.; Devos, S.; Desmet, A.-S.; Zavala Marchan, J. C.; Venneman, T.; Ghassabeh, G. H.; Sedeyn, K.; Ballegeer, M.; Vanheerswynghels, M.; De Wolf, C.; Demol, H.; Vanhaverbeke, P.; Lonigro, C.; Bockstal, V.; Rinaldi, M.; Abdelnabi, R.; Neyts, J.; Marqusee, S.; Lambrecht, B. N.; Callewaert, N.; Remaut, H.; Saelens, X.; Schepens, B.

10.1101/2023.03.10.531533 — microbiology — Posted on 2023-06-20

1753 Integrated signaling and transcriptome analysis reveals Src-family kinase individualities and novel pathways controlled by their constitutive activity

Koutras, N.; Morfos, V.; Konnaris, K.; Kouvela, A.; Shaukat, A. N.; Stathopoulos, C.; Stamatopoulou, V.; Nika, K.

10.1101/2022.09.30.510317 — immunology — Posted on 2023-06-20

1754 A SARS-CoV-2 peptide vaccine which elicits T-cell responses in mice but does not protect against infection or disease

Baxter, V. K.; Anderson, E. J.; Taft-Benz, S. A.; Olsen, K. S.; Sambade, M.; Gentry, K. M.; Beck, W. A.; Garness, J.; Woods, A.; Fini, M.; Carpenter, B.; Smith, C. C.; Heise, M. T.; Vincent, B. G.; Rubinsteyn, A.

10.1101/2022.02.22.481499 — immunology — Posted on 2023-06-20

1755 Interaction of spatial attention and the associated reward value of audiovisual stimuli

Vakhrushev, R.; Pooresmaeili, A.

10.1101/2023.06.18.545478 — neuroscience — Posted on 2023-06-20

1756 Metagenomics uncovers dietary adaptations for chitin digestion in the gut microbiota of convergent myrmecophagous mammals

Teullet, S.; Tilak, M.-K.; Magdeleine, A.; Schaub, R.; Weyer, N. M.; Panaino, W.; Fuller, A.; Loughry, W. J.; Avenant, N. L.; de Thoisy, B.; Borrel, G.; Delsuc, F.

10.1101/2023.04.21.537829 — evolutionary biology — Posted on 2023-06-20

1757 A low dimensional manifold of human exploration and exploitation behavior reveals behavioral states of apathy and anxiety

Yan, X.; Ebitz, B.; Grissom, N.; Darrow, D.; Herman, A.

10.1101/2023.06.19.545645 — neuroscience — Posted on 2023-06-20

1758 Single-neuron and population measures of neuronal activity in working memory tasks

Mozumder, R.; Constantinidis, C.

10.1101/2023.06.18.545508 — neuroscience — Posted on 2023-06-20

1759 The ancestral chromatin landscape of land plants

Hisanaga, T.; Wu, S.; Schafran, P.; Axelsson, E.; Akimcheva, S.; Dolan, L.; Li, F.-W.; Berger, F.

10.1101/2022.10.21.513199 — genomics — Posted on 2023-06-20

1760 Patterning ganglionic eminences in developing human brain organoids using morphogen gradient inducing device

Pak, C.; Pavon, N.; Diep, K.; Yang, F.; Sebastian, R.; Martinez-Martin, B.; Ranjan, R.; Sun, Y.

10.1101/2023.06.20.545705 — neuroscience — Posted on 2023-06-20

1761 Converging evidence that left extrastriate body area supports visual sensitivity to social interactions

Gandolfo, M.; Abassi, E.; Balgova, E.; Downing, P. E.; Papeo, L.; Koldewyn, K.

10.1101/2023.05.23.541943 — neuroscience — Posted on 2023-06-20

1762 Stimulus-specific enhancement of responses in mouse primary visual cortex mediated by GABA release from VIP cells

Kaneko, M.; Hoseini, M. S.; Waschek, J. A.; Stryker, M. P.

10.1101/2023.06.19.545641 — neuroscience — Posted on 2023-06-20

1763 A reproducible benchmark of denoising strategies in resting-state fMRI connectivity using fMRIPrep and Nilearn

Wang, H.-T.; Meisler, S. L.; Sharmarke, H.; Clarke, N.; Gensollen, N.; Markiewicz, C. J.; Paugam, F.; Thirion, B.; Bellec, P.

10.1101/2023.04.18.537240 — neuroscience — Posted on 2023-06-20

1764 In vivo ephaptic coupling allows memory network formation

Pinotsis, D.; Miller, E. K.

10.1101/2023.02.28.530474 — neuroscience — Posted on 2023-06-20

1765 Machine learning-based approach KEVOLVE efficiently identifies SARS-CoV-2 variant-specific genomic signatures

Lebatteux, D.; Gantt, S.; Boucoiran, I.; Soudeyns, H.; Diallo, A. B.

10.1101/2022.02.07.479343 — bioinformatics — Posted on 2023-06-20

1766 Haplotype-resolved assembly of the African catfish (Clarias gariepinus) provides insights for semi-terrestrial adaptation of airbreathing catfishes

Nguinkal, J. A.; Zoclanclounon, Y. A. B.; Brunner, R. M.; Goldammer, T.

10.1101/2023.03.23.533919 — genomics — Posted on 2023-06-20

1767 SNP discovery by exome capture and resequencing in a pea genetic resource collection

Aubert, G.; Kreplak, J.; Leveugle, M.; Duborjal, H.; Klein, A.; Boucherot, K.; Vieille, E.; Chabert-Martinello, M.; Cruaud, C.; Bourion, V.; Lejeune-Henaut, I.; Pilet-Nayel, M.-L.; Bouchenak-Khelladi, Y.; Francillonne, N.; Tayeh, N.; Pichon, J.-P.; Riviere, N.; Burstin, J.

10.1101/2022.08.03.502586 — genomics — Posted on 2023-06-20

1768 Ocean-wide comparisons of mesopelagic planktonic community structures

Rigonato, J.; Budinich, M.; Murillo, A. A.; Brandao, M. C.; Pierella Karlusich, J. J.; Soviadan, Y. D.; Gregory, A. C.; Endo, H.; Kokoszka, F.; Vik, D.; Henry, N.; Fremont, P.; Labadie, K.; Zayed, A. A.; Dimier, C.; Picheral, M.; Searson, S.; Poulain, J.; Kandels, S.; Pesant, S.; Karsenti, E.; Bork, P.; Bowler, C.; de Vargas, C.; Eveillard, D.; Gehlen, M.; Iudicone, D.; Lombard, F.; Ogata, H.; Stemmann, L.; Sullivan, M. B.; Sunagawa, S.; Wincker, P.; Chaffron, S.; Jaillon, O.

10.1101/2021.02.26.433055 — ecology — Posted on 2023-06-20

1769 Controlling target brain regions by optimal selection of input nodes

Manjunatha, K. K. H.; Baron, G.; Benozzo, D.; Silvestri, E.; Corbetta, M.; Chiuso, A.; Bertoldo, A.; Suweis, S.; Allegra, M.

10.1101/2023.06.19.545527 — neuroscience — Posted on 2023-06-20

1770 Detection of threshold-level stimuli modulated by temporal predictions of the cerebellum

Andersen, L. M.; Dalal, S. S.

10.1101/2023.06.20.545246 — neuroscience — Posted on 2023-06-20

1771 Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasite developmental stage differs between behaviors

Rigaud, T.; Balourdet, A.; Bauer, A.

10.1101/2023.04.25.538244 — zoology — Posted on 2023-06-20

1772 The role of BST4 in the pyrenoid of Chlamydomonas reinhardtii

Adler, L.; Lau, C. S.; Shaikh, K. M.; Maldegem, K. v.; Payne-Dwyer, A. L.; Lefoulon, C.; Girr, P.; Atkinson, N.; Barrett, J.; Emrich-Mills, T. Z.; Dukic, E.; Blatt, M. R.; Leake, M.; Peltier, G.; Spetea, C.; McCormick, A. J.; Mackinder, L. C.; Walker, C. E.

10.1101/2023.06.15.545204 — plant biology — Posted on 2023-06-20

1773 The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

Iyer, R. S.; Needham, S. R.; Galdadas, I.; Davis, B. M.; Roberts, S. K.; Man, R. C.; Zanetti-Domingues, L. C.; Clarke, D. T.; Fruhwirth, G. O.; Parker, P. J.; Rolfe, D. J.; Gervasio, F. L.; Martin-Fernandez, M. L.

10.1101/2023.06.16.545259 — cancer biology — Posted on 2023-06-20

1774 Improved interpretability of bacterial genome-wide associations using gene cluster centric k-mers

Neubauer, H.; Galardini, M.

10.1101/2023.04.11.536385 — bioinformatics — Posted on 2023-06-20

1775 Evolutionary history of mammalian UDP-glucuronosyltransferase (UGT)1 and UGT2 families: the emergence of UGT2B subfamily in eutherians after the diversification of flowering plants

Kawai, Y. K.; Sano, K.; Ikenaka, Y.; Nakayama, S. M. M.; Kondo, M.; Kubota, A.; Ishizuka, M.

10.1101/2021.08.20.457063 — evolutionary biology — Posted on 2023-06-20

1776 Ets1 and IL17RA cooperate to regulate autoimmune responses as well as skin immunity to Staphylococcus aureus

Battaglia, M. C.; Sunshine, A.; Luo, W.; Jin, R.; Stith, A.; Lindemann, M.; Miller, L. S.; Sinha, S.; Wohlfert, E.; Garrett-Sinha, L. A.

10.1101/2023.06.19.545307 — immunology — Posted on 2023-06-20

1777 Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation

Zein, L.; Grossmann, J.; Swoboda, H.; Borgel, C.; Wilke, B.; Awe, S.; Nist, A.; Stiewe, T.; Stehling, O.; Freibert, S.-A.; Adhikary, T.; Chung, H.-R.

10.1101/2022.11.22.516855 — immunology — Posted on 2023-06-20

1778 Somnotate: A probabilistic sleep stage classifier for studying vigilance state transitions

Brodersen, P. J. N.; Alfonsa, H.; Krone, L. B.; Blanco-Duque, C.; Fisk, A. S.; Flaherty, S. J.; Guillaumin, M. C. C.; Huang, Y.-G.; Kahn, M. C.; McKillop, L. E.; Milinski, L.; Taylor, L.; Thomas, C. W.; Yamagata, T.; Foster, R. G.; Vyazovskiy, V. V.; Akerman, C. J.

10.1101/2021.10.06.463356 — neuroscience — Posted on 2023-06-20

1779 Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

Aguilar Calvo, P.; Malik, A.; Sandoval, D.; Barback, C.; Orru, C.; Standke, H.; Thomas, O.; Dwyer, C.; Pizzo, D.; Bapat, J.; Soldau, K.; Ogawa, R.; Riley, M.; Nilsson, P.; kraus, a.; caughey, b.; Iliff, J.; Esko, J.; Vera, D.; Sigurdson, C. J.

10.1101/2023.06.19.545528 — pathology — Posted on 2023-06-20

1780 The membrane-cytoplasmic linker defines activity of FtsH proteases

Mawla, G. D.; Kamal, S. M.; Cao, L.; Purhonen, P.; Hebert, H.; Sauer, R. T.; Baker, T. A.; Römling, U.

10.1101/2023.06.19.545564 — biochemistry — Posted on 2023-06-20

1781 Differing structures of galactoglucomannan in eudicots and non-eudicot angiosperms

Ishida, K.; Ohba, Y.; Yoshimi, Y.; Wilson, L. F.; Echevarria-Poza, A.; Yu, L.; Iwai, H.; Dupree, P.

10.1101/2023.06.18.545452 — biochemistry — Posted on 2023-06-20

1782 Evolutionary innovations in germline biology of placental mammals revealed by transcriptomics of first wave spermatogenesis in opossum

Marshall, K. L.; Stadtmauer, D. J.; Maziarz, J.; Wagner, G.; Lesch, B. J.

10.1101/2023.06.17.545442 — genomics — Posted on 2023-06-20

1783 Contrasting responses to aridity by different-sized decomposers cause similar decomposition rates across a precipitation gradient

Torsekar, V. R.; Sagi, N.; Johnson, A. D.; Hawlena, Y.; Gavish-Regev, E.; Hawlena, D.

10.1101/2023.06.04.541603 — ecology — Posted on 2023-06-20

1784 CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Adolph, M. B.; Garje, A. S.; Balakrishnan, S.; Morati, F.; Modesti, M.; Chazin, W. J.; Cortez, D.

10.1101/2023.06.19.545603 — molecular biology — Posted on 2023-06-19

1785 Diversification of Nucleoside Analogues as Potent Antiviral Drug Leads

Scheeff, S.; Wang, Y.; Lyu, M.-Y.; Nasiri Ahmadabadi, B.; Hau, S. C. K.; Hui, T. K. C.; Zhang, Y.; Zuo, Z.; Chan, R. W. Y.; Ng, B. W.-L.

10.1101/2023.06.17.545395 — microbiology — Posted on 2023-06-20

1786 Distinct functions of TIR1 and AFB1 receptors in auxin signalling

Chen, H.; Li, L.; Zou, M.; Qi, L.; Friml, J.

10.1101/2023.01.05.522749 — plant biology — Posted on 2023-06-20

1787 Benchmarking long-read genome sequence alignment tools for human genomics applications

LoTempio, J. E.; Delot, E.; Vilain, E.

10.1101/2021.07.09.451840 — bioinformatics — Posted on 2023-06-20

1788 Development of a rapid and cost-effective multiplex PCR-Nanopore sequencing assay for accurate diagnosis of four tilapia pathogens

Delamare-Deboutteville, J.; Meetmetta, W.; Pimsannil, K.; Gan, H. M.; Kayansamruaj, P.; Khor Li Imm, L.; Chadag Mohan, V.; Dong, H. T.; Senapin, S.

10.1101/2023.05.13.540096 — genomics — Posted on 2023-06-20

1789 Profiling of the Helicobacter pylori redox switch HP1021 regulon using a multi-omics approach

Noszka, M.; Strzalka, A.; Muraszko, J.; Kolenda, R.; Meng, C.; Ludwig, C.; Stingl, K.; Zawilak-Pawlik, A.

10.1101/2023.06.19.544759 — molecular biology — Posted on 2023-06-19

1790 Sequence features of transcriptional activation domains are consistent with the surfactant mechanism of gene activation

Broyles, B. B.; Erkina, T. Y.; Maris, T. P.; Gutierrez, A. T.; Coil, D. A.; Wagner, T. M.; Class, C. A.; Erkine, A. M.

10.1101/2023.06.18.545482 — molecular biology — Posted on 2023-06-19

1791 Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough

Pavlikova, Z. C.; Miletinova, P.; Pospisilova, K.; Roithova, A.; Zahonova, K.; Durante, I.; Kachale, A.; Becker, T.; Lukes, J.; Paris, Z.; Beznoskova, P.; Valasek, L. S.

10.1101/2023.06.19.543857 — molecular biology — Posted on 2023-06-19

1792 Humanized yeast to study the role of human ECE-1 isoforms in apoptosis in congenital heart diseases

Xie, H.; Huang, Y.; Louis, E. J.; Xie, X.

10.1101/2023.06.19.545519 — molecular biology — Posted on 2023-06-19

1793 Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth

Sharma, A.; Mistriel-Zerbib, S.; Najar, R. A.; Engal, E.; Bentata, M.; Taqatqa, N.; Dahan, S.; Cohen, K.; Jaffe-Herman, S.; Geminder, O.; Baker, M.; Nevo, Y.; Plaschkes, I.; Kay, G.; Drier, Y.; Berger, M.; Salton, M.

10.1101/2022.11.30.518304 — molecular biology — Posted on 2023-06-20

1794 Lego-like Mixing and Matching of Engineered Bacteria Configure Full Subtractor and Adder Through an Artificial Neural Network Type Architecture

Bonnerjee, D.; Chakraborty, S.; Bagh, S.

10.1101/2023.06.15.545057 — synthetic biology — Posted on 2023-06-20

1795 Intraspecies variability in plant and soil chemical properties in a common garden plantation of the energy crop Populus

Craig, M. E.; Harman-Ware, A. E.; Cope, K. R.; Kalluri, U.

10.1101/2023.06.16.545338 — plant biology — Posted on 2023-06-19

1796 Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

Matsui, M.; Lynch, L. E.; Distefano, I.; Galante, A.; Gomez-Banoy, N.; Wang, H.-G.; Gade, A. R.; Sinden, D. S.; Wei, E. Q.; Barnett, A. S.; Johnson, K.; Rubio-Navarro, A.; Li, A. K.; Marx, S. O.; McGraw, T. E.; Thornton, P.; Timothy, K. W.; Lo, J. C.; Pitt, G. S.

10.1101/2023.06.16.544987 — physiology — Posted on 2023-06-19

1797 intI1 primer selection for class 1 integron integrase gene and transcript quantification - validation and application for monitoring intl1 gene abundance within septic tanks in Thailand

Okonkwo, V. O.; Cholet, F.; Ijaz, U. Z.; Koottatep, T.; Pussayanavin, T.; Polpraset, C.; Sloan, W. T.; Connelly, S.; Smith, C. J.

10.1101/2023.06.19.545554 — molecular biology — Posted on 2023-06-19

1798 Integrative metabolomics and proteomics allow the global intracellular characterization of Bacillus subtilis cells and spores.

Huang, Y.; Swarge, B. N.; Roseboom, W.; Bleeker, J. D.; Brul, S.; Setlow, P.; Kramer, G.

10.1101/2023.06.19.545067 — microbiology — Posted on 2023-06-19

1799 The ultrastructural nature of human oocytes' cytoplasmatic abnormalities and the role of cytoskeleton dysfunction

Tatickova, M.; Trebichalska, Z.; Kyjovska, D.; Otevrel, P.; Kloudova, S.; Holubcova, Z.

10.1101/2023.04.20.537668 — cell biology — Posted on 2023-06-20

1800 DnaK duplicates and regionally evolves for the increase of proteomic complexity in bacteria

Pan, Z.; Zhuo, L.; Wan, T.-y.; Chen, R.-y.; Li, Y.-z.

10.1101/2023.06.19.545549 — microbiology — Posted on 2023-06-19

1801 Meta-metabolomic Responses of River Biofilms to Cobalt Exposure and Use of Dose-response Model Trends as an Indicator of Effects

Colas, S.; Marie, B.; Milghe-Poutingon, M.; Lot, M.-C.; Boullemant, A.; Fortin, C.; Le Faucheur, S.

10.1101/2023.06.19.545533 — microbiology — Posted on 2023-06-19

1802 Mechanism of action of Vitamin D (1,25-(OH)2-D3) on ovarian follicle growth: implications for women with Vitamin D deficiency and PCOS

Seaward Brain, H. P.; Georgiou, C.; Mason, H. D.; Rice, S.

10.1101/2023.06.16.545289 — physiology — Posted on 2023-06-19

1803 Endometrial cyclin A2 deficiency is associated with human female infertility and is recapitulated in a conditional knockout mouse model

Aljubran, F.; Schumacher, K.; Graham, A.; Gunewardena, S.; Marsh, C.; Lydic, M.; Holoch, K.; Nothnick, W. B.

10.1101/2023.06.16.545284 — physiology — Posted on 2023-06-19

1804 Pyranthiones/Pyrones: Click and Release Donors for Subcellular Hydrogen Sulfide Delivery and Labeling

Huang, W.; Escorihuela, J.; Laughlin, S. T.

10.1101/2023.06.19.545622 — biochemistry — Posted on 2023-06-19

1805 Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

Jiang, Y.; Li, Z.; Sui, D.; Sharma, G.; Wang, T.; MacRenaris, K.; Takahashi, H.; Merz, K.; Hu, J.

10.1101/2023.06.19.545588 — biochemistry — Posted on 2023-06-19

1806 Poverty shapes the transcriptome of immune cells

Arnold, N. S.; Resztak, J.; Witonsky, D.; Alazizi, A.; Hooten, N. N.; Evans, M. K.; Odera-Marah, V.; Dluzen, D. F.; Pique-Regi, R.; Luca, F.

10.1101/2022.12.06.517536 — genomics — Posted on 2023-06-19

1807 Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis

Almeida, D. V.; Li, S.-Y.; Lee, J.; Hafkin, B.; Mdluli, K.; Fotouhi, N.; Nuermberger, E.

10.1101/2023.06.18.545492 — microbiology — Posted on 2023-06-19

1808 Timing of dense granule biogenesis in asexual malaria parasites

Vallintine, T.; van Ooij, C.

10.1101/2023.06.19.545557 — microbiology — Posted on 2023-06-19

1809 Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis.

Wang, F.; Liu, X.; Huang, F.; Zhou, Y.; Wang, X.; Song, Z.; Wang, S.; Wang, X.; Shi, D.; Ruan, G.; Ji, X.; Zhang, E.; Tan, Z.; Ye, Y.; Wang, C.; Zhu, J.; Wang, W.

10.1101/2023.06.02.543432 — microbiology — Posted on 2023-06-19

1810 A sweet new set of inducible and constitutive promoters for haloarchaea

Rados, T.; Andre, K.; Cerletti, M.; Bisson, A.

10.1101/2023.04.06.535941 — microbiology — Posted on 2023-06-19

1811 Regional pulmonary perfusion, blood volume, and their relationship change during early ARDS in an experimental study

Santos, A.; Motta-Ribeiro, G. C.; De Prost, N.; Tucci, M. R.; Wellman, T. J.; Vidal Melo, M. F.; Winkler, T.

10.1101/2023.06.19.545593 — physiology — Posted on 2023-06-19

1812 Maternal, placental and fetal response to a non-viral, polymetric nanoparticle gene therapy in nonhuman primates

Wilson, R. L.; Kropp Schmidt, J.; Davenport, B. N.; Ren, E.; Keding, L. T.; Shaw, S.; Schotzko, M. L.; Antony, K.; Simmons, H. A.; Golos, T.; Jones, H.

10.1101/2023.06.16.545278 — physiology — Posted on 2023-06-19

1813 Bimodular Architecture of Bacterial Effector SAP05 Drives Ubiquitin-Independent Targeted Protein Degradation

Liu, Q.; Maqbool, A.; Mirkin, F. G.; Singh, Y.; Stevenson, C. E.; Lawson, D. M.; Kamoun, S.; Huang, W.; Hogenhout, S. A.

10.1101/2023.06.19.545293 — biochemistry — Posted on 2023-06-19

1814 KaScape: A sequencing-based method for global characterization of protein-DNA binding affinity

Chen, H.; Xu, Y.; Jin, J.; Su, X.

10.1101/2023.06.19.545523 — biochemistry — Posted on 2023-06-19

1815 Collective synchrony of mating signals modulated by ecological cues and social signals in bioluminescent sea fireflies

Hensley, N. M.; Rivers, T. J.; Gerrish, G. A.; Oakley, T. H.

10.1101/2023.06.16.545275 — animal behavior and cognition — Posted on 2023-06-19

1816 Reproductive biology of farmed lumpfish (Cyclopterus lumpus): Gonadal development and associated profiles of selected endocrine factors.

Mlingi, F. T.; Puvanendran, V.; Burgerhout, E.; Guercini, E.; Mommens, M.; Hansen, O. J.; Miguez, M. F.; Presa, P.; Tveiten, H.; Tomkiewicz, J.; Kjorsvik, E.

10.1101/2023.06.16.545335 — animal behavior and cognition — Posted on 2023-06-19

1817 Deep learning image analysis for filamentous fungi taxonomic classification: Dealing with small data sets with class imbalance and hierarchical grouping

Stiller, S.; Duenas, J. F.; Hempel, S.; Rillig, M. C.; Ryo, M.

10.1101/2023.06.19.545596 — microbiology — Posted on 2023-06-19

1818 Knockout of HD domain 5-nucleotidase in T. brucei triggers cell death linked to DNA damage and downregulation of glutamine uptake

Deng, Y. W.; Pontikos, M. A.; Baniasadi, H.; Williams, N. S.; Phillips, M. A.

10.1101/2023.06.19.545529 — microbiology — Posted on 2023-06-19

1819 Dysregulated Platelet Function and Thrombosis in Patients with Post-Acute Sequelae of COVID-19

Aggarwal, A.; Singh, T. K.; Pham, M.; Godwin, M.; Chen, R.; McIntyre, T. M.; Chung, M. K.; Jennings, C.; Ali, M.; Park, H.; Englund, K.; Khorana, A. A.; Svensson, L.; Kapadia, S. R.; McCrae, K. R.; Cameron, S. J.

10.1101/2023.06.18.545507 — pharmacology and toxicology — Posted on 2023-06-19

1820 SARS-CoV-2 variants of concern exhibit differential gastro-intestinal tropism and pathogenesis in the Syrian golden hamster model.

Nagraj, S. K.; Joy, C. M.; Narayan, R.; Shiraz, R.; Kaur, S.; Khatun, O.; Dubey, S.; Tripathi, S.

10.1101/2023.06.19.545534 — pathology — Posted on 2023-06-19

1821 Listeria monocytogenes infection in pregnancy macaques alters the maternal gut microbiome

Hugon, A. M.; Golos, T.

10.1101/2023.06.18.545418 — microbiology — Posted on 2023-06-19

1822 High-accuracy meets high-throughput for microbiome profiling with near full-length 16S rRNA amplicon sequencing on the Nanopore platform

Lin, X.; Waring, K.; Tyson, J.; Ziels, R.

10.1101/2023.06.19.544637 — microbiology — Posted on 2023-06-19

1823 Neurogenomic landscape associated with status-dependent cooperative behavior

Bolton, P. E.; Ryder, T. B.; Dakin, R.; Houtz, J. L.; Moore, I. T.; Balakrishnan, C. N.; Horton, B. M.

10.1101/2022.10.05.510848 — evolutionary biology — Posted on 2023-06-19

1824 Inter and Intralaminar Excitation of Parvalbumin Interneurons in Mouse Barrel Cortex

Scheuer, K. S.; Jansson, A. M.; Zhao, X.; Jackson, M. B.

10.1101/2023.06.02.543448 — neuroscience — Posted on 2023-06-19

1825 Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits

Pratelli, M.; Hakimi, A. M.; Thaker, A.; Li, H.; Godavarthi, S.; Spitzer, N. C.

10.1101/2022.06.16.496480 — neuroscience — Posted on 2023-06-19

1826 A novel 4D fMRI clustering technique to examine event-related spatiotemporal dynamics of face processing in naturalistic stimuli

Ekstrand, C.

10.1101/2023.06.15.545143 — neuroscience — Posted on 2023-06-19

1827 Protein-Protein interaction and quantitative phosphoproteomic studies reveal potential mitochondrial substrates of protein phosphatase 2A-B'ζ holoenzyme

Elshobaky, A.; Lillo, C.; Hoden, K.; Kataya, A.

10.1101/2023.05.20.541568 — plant biology — Posted on 2023-06-19

1828 First Chromosome-scale Genome Assembly of Arundo donax

Ren, M.; Liu, F.; Han, X.

10.1101/2023.06.18.544523 — plant biology — Posted on 2023-06-19

1829 Combining experiments and simulations to examine the temperature-dependent behaviour of a disordered protein

Pesce, F.; Lindorff-Larsen, K.

10.1101/2023.03.04.531094 — biophysics — Posted on 2023-06-19

1830 CellTools algorithm for mapping scRNA-seq query cells to the reference dataset improves the classification of resilient and susceptible retinal ganglion cell types

Rheaume, B. A.; Xing, J.; Theune, W. C.; DeRosa, S. G.; Trakhtenberg, E. F.

10.1101/2021.10.15.464552 — bioinformatics — Posted on 2023-06-19

1831 Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery

10.1101/2023.04.30.535834 — bioengineering — Posted on 2023-06-19

1832 Enhanced capillary pumping using open-channel capillary trees with integrated paper pads

Tokihiro, J. C.; Tu, W.-c.; Berthier, J.; Lee, J. J.; Dostie, A. M.; Khor, J. W.; Eakman, M.; Theberge, A. B.; Berthier, E.

10.1101/2022.07.15.500252 — bioengineering — Posted on 2023-06-19

1833 Optimization of RNA Pepper sensors for the detection of arbitrary RNA targets

Tang, A.; Afasizheva, A.; Cano, C.; Plath, K.; Black, D. L.; Franco, E.

10.1101/2023.06.01.543282 — biochemistry — Posted on 2023-06-19

1834 Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay for intergenerational status transmission, careers, and health

Akimova, E. T.; Wolfram, T.; Ding, X.; Tropf, F. C.; Mills, M. C.

10.1101/2023.03.31.534944 — genetics — Posted on 2023-06-19

1835 Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae

Le Naour--Vernet, M.; Charriat, F.; Gracy, J.; Cros-Arteil, S.; Ravel, S.; Veillet, F.; Meusnier, I.; Padilla, A.; Kroj, T.; Cesari, S.; Gladieux, P.

10.1101/2023.03.16.532886 — evolutionary biology — Posted on 2023-06-19

1836 Metabolomic analysis of Drosophila melanogaster larvae lacking Pyruvate kinase

Heidarian, Y.; Tourigny, J. P.; Fasteen, T. D.; Mahmoudzadeh, N. H.; Hurlburt, A. J.; Nemkov, T.; Reisz, J. A.; D'Alessandro, A.; Tennessen, J. M.

10.1101/2023.06.05.543743 — developmental biology — Posted on 2023-06-19

1837 Characterization of genetic and molecular tools for studying the endogenous expression of Lactate dehydrogenase in Drosophila melanogaster

Rai, M.; Carter, S. M.; Shefali, S. A.; Chawla, G.; Tennessen, J. M.

10.1101/2023.06.15.545165 — developmental biology — Posted on 2023-06-19

1838 A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

Maher, S. P.; Bakowski, M. A.; Vantaux, A.; Flannery, E. L.; Andolina, C.; Gupta, M.; Antonova-Koch, Y.; Argomaniz, M.; Monica, C.-M.; Brice, C.; Chao, A. T.; Chatterjee, A. K.; Cheng, W. T.; Cooper, C. A.; Karissa, C.; Galinski, M. R.; Harupa-Chung, A.; Ji, H.; Joseph, S. B.; Lenz, T.; Lonardi, S.; Matheson, J.; Mikolajczak, S. A.; Padin-Irizarry, V.; Pan, K.; Peneau, J.; Prudhomme, J.; Roesch, C.; Ruberto, A. A.; Sabnis, S. S.; Saney, C. L.; Sattabongkot, J.; Sereshki, S.; Suriyakan, S.; Timothy, M.; Ubalee, R.; Wang, Y.; Wasisakun, P.; Yin, J.; McNamara, C. W.; Joyner, C. J.; Nosten, F.; Wi

10.1101/2023.01.31.526483 — cell biology — Posted on 2023-06-19

1839 Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin-antitoxin system

Baerentsen, R. L.; Nielsen, S. V.; Skjerning, R. B.; Lyngso, J.; Bisiak, F.; Pedersen, J. S.; Gerdes, K.; Sorensen, M. A.; Brodersen, D. E.

10.1101/2022.01.28.478185 — microbiology — Posted on 2023-06-19

1840 Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Wamhoff, E.-C.; Ronsard, L.; Feldman, J.; Knappe, G. A.; Hauser, B. M.; Romanov, A.; Lam, E.; St. Denis, K.; Boucau, J.; Barczak, A. K.; Balazs, A. B.; Schmidt, A.; Lingwood, D.; Bathe, M.

10.1101/2022.08.16.504128 — immunology — Posted on 2023-06-19

1841 Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus

Lemcke, R.; Egebjerg, C.; Berendtsen, N. T.; Egerod, K. L.; Thomsen, A. R.; Pers, T. H.; Christensen, J. P.; Kornum, B. R.

10.1101/2023.03.06.530999 — neuroscience — Posted on 2023-06-19

1842 BackWards - Unveiling the Brain's Topographic Organization of Paraspinal Sensory Input

Guekos, A.; Cole, D. M.; Doerig, M. A.; Staempfli, P.; Schibli, L.; Schuetz, P. A.; Schweinhardt, P.; Meier, M. L.

10.1101/2022.08.05.502912 — neuroscience — Posted on 2023-06-19

1843 Local prediction-learning in high-dimensional spaces enables neural networks to plan

Stoeckl, C.; Maass, W.

10.1101/2022.10.17.512572 — neuroscience — Posted on 2023-06-19

1844 Do chromosome rearrangements fix by genetic drift or natural selection? A test in Brenthis butterflies

Mackintosh, A.; Vila, R.; Martin, S. H.; Setter, D.; Lohse, K.

10.1101/2023.06.16.545248 — evolutionary biology — Posted on 2023-06-19

1845 Quantifying the coverage of the human proteome with renewable antibodies

Ayoubi, R.; Ryan, J.; Fotouhi, M.; Alshafie, W.; Bolivar, S. G.; Moleon, V. R.; Reintsch, W.; Eckmann, P.; Worrall, D.; McDowell, I.; Southern, K.; Durcan, T. M.; Brown, C. M.; Bandrowski, A. E.; Virk, H. S.; Edwards, A. M.; McPherson, P. S.; Laflamme, C.

10.1101/2023.06.01.543292 — molecular biology — Posted on 2023-06-19

1846 A high-sensitivity ELISA for detection of human FGF18 in culture supernatants from tumor cell lines

Tsuchiya, Y.; Komazawa-Sakon, S.; Tanaka, M.; Kanakogi, T.; Moriwaki, K.; Akiba, H.; Yagita, H.; Okumura, K.; Entzminger, K.; Okumura, C.; Maruyama, T.; Nakano, H.

10.1101/2023.06.16.545249 — cancer biology — Posted on 2023-06-19

1847 An Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis

Leslie, T. K.; Tripp, A.; James, A. D.; Fraser, S. P.; Nelson, M.; Toss, M. S.; Fadhil, W.; Salvage, S. C.; Arias Garcia, M.; Beykou, M.; Rakha, E.; Speirs, V.; Bakal, C.; Poulogiannis, G.; Djamgoz, M.; Jackson, A. P.; Matthews, H. R.; Huang, C. L.-H.; Holding, A.; Chawla, S.; Brackenbury, W. J.

10.1101/2023.06.16.545273 — cancer biology — Posted on 2023-06-19

1848 OpenSIM: open source microscope add-on for structured illumination microscopy

Hannebelle, M. T. M.; Raeth, E.; Leitao, S.; Lukes, T.; Pospisil, J.; Toniolo, C.; Venzin, O. F.; Chrisnandy, A.; Swain, P. P.; Ronceray, N.; Lutolf, M. P.; Oates, A. C.; Hagen, G. M.; Lasser, T.; Radenovic, A.; Mckinney, J. D.; Fantner, G. E.

10.1101/2023.06.16.545316 — bioengineering — Posted on 2023-06-19

1849 Dopamine functionalized, red carbon quantum dots for in vivo bioimaging, cancer therapeutics, and neuronal differentiation

Yadav, P.; Benner, D. G.; Varshney, R.; Kansara, K.; Shah, K.; Dahle, L.; Kumar, A.; Rawal, R.; Gupta, S.; Bhatia, D.

10.1101/2023.06.16.545347 — bioengineering — Posted on 2023-06-19

1850 Assembly of sequences of Northern China alligatorweed identifies processes and gene ontologies associated with invasiveness and provides genomic resources for population and gene regulation studies

Horvath, D.; Wang, Y.; Meng, F.; Neubauer, M.; Dasheng, L.

10.1101/2023.06.16.545218 — ecology — Posted on 2023-06-19

1851 Turning Ecology Against Pesticide Resistance: Exploiting Competition in Pest Populations Through Pesticide Use

Guariento, R. D.; Almeida-Gomes, M.; Oliveira-Santos, L. G. R.; Pires, A. P. F.; Roque, F. d. O.

10.1101/2023.06.16.545263 — ecology — Posted on 2023-06-19

1852 Temporally resolved early BMP-driven transcriptional cascade during human amnion specification

Sekulovski, N.; Wettstein, J. C.; Carleton, A. E.; Taniguchi, L. E.; Ma, X.; Rao, S.; Kropp Schmidt, J.; Golos, T.; Lin, C.-W.; Taniguchi, K.

10.1101/2023.06.19.545574 — developmental biology — Posted on 2023-06-19

1853 Neural correlates of online action preparation

Shahbazi, M.; Ariani, G.; Kashefi, M.; Pruszynski, J. A.; Diedrichsen, J.

10.1101/2023.06.19.545487 — neuroscience — Posted on 2023-06-19

1854 Transcriptomic profiling reveals a pro-nociceptive role for Angiotensin II in inflammatory bowel disease

Higham, J. P.; Bhebhe, C. N.; Gupta, R. A.; Tranter, M.; Barakat, F. M.; Dogra, H.; Bab, N.; Wozniak, E.; Barker, K. H.; Wilson, C. H.; Mein, C.; Raine, T.; Cox, J. J.; Wood, J. N.; Croft, N.; Wright, P.; Bulmer, D. C.

10.1101/2023.06.16.545265 — neuroscience — Posted on 2023-06-19

1855 Male and female syringeal muscles exhibit superfast shortening velocities in Zebra finches

Gladman, N. W.; Elemans, C. P.

10.1101/2023.06.19.545584 — zoology — Posted on 2023-06-19

1856 The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

Martin-Fernandez, M. L.; Iyer, S.; Needham, S. R.; Galgadas, I.; Davis, B. M.; Roberts, S. K.; Man, R. C.; Zanetti-Domingues, L. C.; Clarke, D. T.; Fruhwirth, G. O.; Parker, P. J.; Rolfe, D. J.; Gervasio, F. L.

10.1101/2023.06.16.545259 — cancer biology — Posted on 2023-06-19

1857 GTPase activating protein DLC1 spatio-temporally regulates Rho signaling

Heydasch, M.; Hinderling, L.; van Unen, J.; Dobrzynski, M.; Pertz, O.

10.1101/2023.06.19.545304 — cell biology — Posted on 2023-06-19

1858 Proteomics reveals how the tardigrade damage suppressor protein teaches transfected human cells to survive UV-C stress

Shaba, E.; Landi, C.; Marzocchi, C.; Vantaggiato, L.; Bini, L.; Ricci, C.; Cantara, S.

10.1101/2023.06.19.545547 — cell biology — Posted on 2023-06-19

1859 A resource for development and comparison of multi-modal brain 3T MRI harmonisation approaches

Warrington, S.; Ntata, A.; Mougin, O.; Campbell, J.; Torchi, A.; Craig, M.; Alfaro-Almagro, F.; Miller, K.; Morgan, P.; Jenkinson, M.; Sotiropoulos, S.

10.1101/2023.06.16.545260 — neuroscience — Posted on 2023-06-19

1860 Characterizing the diversity of enteric neurons using Dopamine Transporter (DAT)-Cre reporter mice

Recinto, S.; Premachandran, S.; Mukherjee, S.; McDonald, A.; Gruenheid, S.; Trudeau, L. E.; Stratton, J. A.

10.1101/2023.06.16.545271 — neuroscience — Posted on 2023-06-19

1861 CyVerse: Cyberinfrastructure for Open Science

Swetnam, T. L.; Antin, P. B.; Bartelme, R.; Bucksch, A.; Camhy, D.; Chism, G.; Choi, I.; Cooksey, A. M.; Cosi, M.; Cowen, C.; Culshaw-Maurer, M.; Davey, R.; Davey, S.; Devisetty, U.; Edgin, T.; Edmonds, A.; Fedorov, D.; Frady, J.; Fonner, J.; Gillan, J. K.; Hossain, I.; Joyce, B.; Lang, K.; Lee, T.; Littin, S.; Mcewen, I.; Merchant, N.; Micklos, D.; Nelson, A.; Ramsey, A.; Roberts, S.; Sarando, P.; Skidmore, E.; Song, J.; Sprinkle, M. M.; Srinivasan, S.; Strootman, J. D.; Stryeck, S.; Tuteja, R.; Vaughn, M.; Wali, M.; Wall, M.; Walls, R.; Wang, L.; Wickizer, T.; Williams, J.; Wregglesworth, J.

10.1101/2023.06.16.545223 — scientific communication and education — Posted on 2023-06-19

1862 Selective plane activation structured illumination microscopy

Temma, K.; Oketani, R.; Kubo, T.; Bando, K.; Maeda, S.; Sugiura, K.; Matsuda, T.; Heintzmann, R.; Kaminishi, T.; Fukuda, K.; Hamasaki, M.; Nagai, T.; Fujita, K.

10.1101/2023.06.19.545558 — biophysics — Posted on 2023-06-19

1863 Large language models are universal biomedical simulators

Schaefer, M.; Reichl, S.; ter Horst, R.; Nicolas, A. M.; Krausgruber, T.; Piras, F.; Stepper, P.; Bock, C.; Samwald, M.

10.1101/2023.06.16.545235 — bioinformatics — Posted on 2023-06-19

1864 Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment

Kandasamy, K.; Fan, X.; Haribalaganesh, R.; Bharanidharan, D.; Sharmila, R.; Krishnadas, R.; Muthukkaruppan, V.; Willoughby, C. E.; Srinivasan, S.

10.1101/2023.06.19.545545 — cell biology — Posted on 2023-06-19

1865 Extracellular Matrix Stiffness Promotes Vascular Smooth Muscle Cell Calcification by Reducing The Levels of Nuclear Actin Monomers

McNeill, M. C.; Chee, F. L.; Ebrhimighaei, R.; Sala Newby, G. B.; Newby, A. C.; Hathway, T.; Annaiah, A. S.; Joseph, S.; Carrabba, M.; Bond, M.

10.1101/2023.06.18.545506 — cell biology — Posted on 2023-06-19

1866 Donor tissue-resident memory-like T and NK cells generate a transient peripheral chimerism in lung transplant recipients, potentially protective from chronic lung allograft dysfunction

Bellmas-Sanz, R.; Hitz, A.-M.; Wiegmann, B.; Kuehne, J. F.; Chichelnitskiy, E.; Kapellos, T. S.; Blaesing, K.-A.; Keil, J.; Beushausen, K.; Sommer, W.; Haendler, K.; Becker, M.; Bassler, K.; Horn, L.-M.; Jonigk, D.; Greer, M.; Haverich, A.; Schultze, J. L.; Ius, F.; Warnecke, G.; Falk, C. S.

10.1101/2023.06.16.543190 — immunology — Posted on 2023-06-19

1867 Endogenous oscillatory rhythms and interactive contingencies jointly influence infant attention during early infant-caregiver interaction

Phillips, E. A. M.; Wass, S.; Goupil, L.; Whitehorn, M.; Bruce-Gardyne, E.; Csolsium, F.; Kaur, N.; Greenwood, E.; Marriott-Haresign, I.

10.1101/2023.06.19.545295 — neuroscience — Posted on 2023-06-19

1868 Cryo-EM structure of the human G-protein coupled receptor 1 (GPR1) - Gi protein complex bound to the chemerin C-terminal nonapeptide

Liu, A.; Liu, Y.; Chen, G.; Lyu, W.; Wang, J.; Liao, Q.; Ye, F.; Zhu, L.; Du, Y.; Ye, R. D.

10.1101/2023.06.03.543554 — pharmacology and toxicology — Posted on 2023-06-19

1869 Literate programming for iterative design-build-test-learn cycles in bioengineering

Petersen, S. D.; Levassor, L.; Pedersen, C. M.; Madsen, J.; Hansen, L. G.; Zhang, J.; Haidar, A. K.; Frandsen, R. J. N.; Weber, T.; Keasling, J. D.; Sonnenschein, N.; Jensen, M. K.

10.1101/2023.06.18.545451 — bioinformatics — Posted on 2023-06-19

1870 Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius erato

Pinheiro de Castro, E. C.; McPherson, J.; Julian, G.; Mattila, A.; Bak, S.; Montgomery, S.; Jiggins, C.

10.1101/2023.01.13.523799 — evolutionary biology — Posted on 2023-06-19

1871 Grazing hinders seed dispersal during crop failure in a declining oak woodland

Vaz, P. G.; Bugalho, M. N.; Fedriani, J.

10.1101/2023.04.14.536763 — ecology — Posted on 2023-06-19

1872 Diffusion model of delipidation in biological sample clearing

Han, J.; Liu, X.; Hou, X.; Zhong, Y.; Chen, Z.; Yang, Z.; Jiang, T.

10.1101/2023.06.18.545453 — neuroscience — Posted on 2023-06-19

1873 First Chromosome-scale Genome Assembly of Arundo donax

Mengmeng, R.; Fupeng, L.; Xiaohong, H.

10.1101/2023.06.18.544523 — plant biology — Posted on 2023-06-19

1874 Initial platelet aggregation in the complex shear environment of a punctured vessel model

Spieker, C. J.; Zavodszky, G.; Mouriaux, C.; Mangin, P. H.; Hoekstra, A. G.

10.1101/2023.05.11.540363 — biophysics — Posted on 2023-06-19

1875 Detecting episodic evolution through Bayesian inference of molecular clock models

Tay, J. H.; Baele, G.; Duchene, S.

10.1101/2023.06.17.545443 — bioinformatics — Posted on 2023-06-19

1876 Context-aware geometric deep learning for protein sequence design

Krapp, L.; Meireles, F.; Abriata, L.; Dal Peraro, M.

10.1101/2023.06.19.545381 — biochemistry — Posted on 2023-06-19

1877 Salivary corticosterone reflects plasmatic levels in a wild seabird.

Carbillet, J.; Saks, L.; Sepp, T.

10.1101/2023.06.16.545258 — ecology — Posted on 2023-06-19

1878 An extension of the Walsh-Hadamard transform to calculate and model epistasis in genetic landscapes of arbitrary shape and complexity

Faure, A. J.; Lehner, B.; Miro Pina, V.; Serrano Colome, C.; Weghorn, D.

10.1101/2023.03.06.531391 — systems biology — Posted on 2023-06-19

1879 Distributed representations of prediction error signals across the cortical hierarchy are synergistic

Gelens, F.; Aijala, J.; Roberts, L.; Komatsu, M.; Uran, C.; Jensen, M. A.; Miller, K. J.; Ince, R. A. A.; Garagnani, M.; Vinck, M.; Canales-Johnson, A.

10.1101/2023.01.12.523735 — neuroscience — Posted on 2023-06-19

1880 Premature Aging and Reduced Cancer Incidence Associated with Near-Complete Body-Wide Myc Inactivation

Wang, H.; Lu, J.; Stevens, T.; Roberts, A.; Mandel, J.; Avula, R.; Ma, B.; Wu, Y.; Wang, J.; Finkel, T.; Van't Land, C.; Vockley, J. E.; Airik, M.; Airik, R.; Muzumdar, R.; Gong, Z.; Torbenson, M. S.; Prochownik, E. V.

10.1101/2023.01.30.526354 — cancer biology — Posted on 2023-06-19

1881 Colonisation debt: when invasion history impacts current range expansion

Morel-Journel, T.; Haond, M.; Dunan, L.; Mailleret, L.; Vercken, E.

10.1101/2022.11.13.516255 — ecology — Posted on 2023-06-19

1882 Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice

Zheng, H.; Li, Q.; Li, S.; Li, Z.; Brotto, M.; Weiss, D.; Prosdocimo, D.; Xu, C.; Reddy, A.; Puchowicz, M.; Zhao, X.; Weitzmann, M. N.; Jain, M. K.; Qu, C.-K.

10.1101/2023.01.09.523031 — cell biology — Posted on 2023-06-19

1883 Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

Weinberger, T.; Messerer, D.; Joppich, M.; Fischer, M.; Garcia, C.; Kumaraswami, K.; Wimmler, V.; Ablinger, S.; Raeuber, S.; Fang, J.; Liu, L.; Liu, W. H.; Winterhalter, J.; Lichti, J.; Tomas, L.; Esfandyari, D.; Percin, G.; Salamanca, S. M.; Hidalgo, A.; Waskow, C.; Engelhardt, S.; Todica, A.; Zimmer, R.; Pridans, C.; Gomez-Perdiguero, E.; Schulz, C.

10.1101/2023.05.08.539799 — immunology — Posted on 2023-06-19

1884 aPEAR: an R package for autonomous visualisation of pathway enrichment networks

Kerseviciute, I.; Gordevicius, J.

10.1101/2023.03.28.534514 — bioinformatics — Posted on 2023-06-19

1885 Advancing terrestrial biodiversity monitoring with satellite remote sensing in the context of the Kunming-Montreal global biodiversity framework

Timmermans, J.; Kissling, D.

10.1101/2022.04.25.489356 — ecology — Posted on 2023-06-19

1886 Multimodal sensory control of motor performance by glycinergic interneurons of the spinal cord deep dorsal horn.

Gradwell, M. A.; Ozeri-Engelhard, N.; Eisdorfer, J. T.; Laflamme, O. D.; Gonzalez, M.; Upadhyay, A.; Aoki, A.; Shrier, T.; Gandhi, M.; Abbas- Zadeh, G.; Oputa, O.; Thackray, J.; Ricci, M.; Yusuf, N.; Keating, J.; Imtiaz, Z.; Alomary, S. A.; Katz, J.; Haas, M.; Hernandez, Y.; Akay, T.; Abraira, V. E.

10.1101/2022.05.21.492933 — neuroscience — Posted on 2023-06-19

1887 Cell Cycle Dependent Orchestration of Surface Layer Biogenesis in Caulobacter crescentus

Herdman, M.; von Kügelgen, A.; Schulze, U.; Wainman, A.; Bharat, T. A. M.

10.1101/2023.06.14.544926 — microbiology — Posted on 2023-06-19

1888 Measuring Neuronal Avalanches to inform Brain-Computer Interfaces

Corsi, M.-C.; Sorrentino, P.; Schwartz, D.; George, N.; Gollo, L.; Chevallier, S.; Hugueville, L.; Kahn, A. E.; Dupont, S.; Bassett, D. S.; Jirsa, V.; De Vico Fallani, F.

10.1101/2022.06.14.495887 — neuroscience — Posted on 2023-06-19

1889 Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder

Miyahara, K.; Tatehana, M.; Kikkawa, T.; Osumi, N.

10.1101/2023.06.01.543326 — developmental biology — Posted on 2023-06-19

1890 When and why does motor preparation arise in recurrent neural network models of motor control?

Schimel, M.; Kao, T.-C.; Hennequin, G.

10.1101/2023.04.03.535429 — neuroscience — Posted on 2023-06-19

1891 Single-cell sequencing of tumor-associated macrophages in a Drosophila model.

Khalili, D.; Mohammed, M.; Kunc, M.; Ankarklev, J.; Theopold, U.

10.1101/2023.06.17.545411 — cancer biology — Posted on 2023-06-19

1892 FixNCut: Single-cell genomics through reversible tissue fixation and dissociation

Jimenez-Gracia, L.; Marchese, D.; Nieto, J. C.; Caratu, G.; Melon-Ardanaz, E.; Gudino, V.; Roth, S.; Wise, K.; Ryan, N. K.; Jensen, K. B.; Hernando-Momblona, X.; Bernardes, J. P.; Tran, F.; Sievers, L. K.; Schreiber, S.; van den Berge, M.; Kole, T.; van der Velde, P. L.; Nawijn, M. C.; Rosenstiel, P.; Batlle, E.; Butler, L. M.; Parish, I. A.; Plummer, J. T.; Gut, I. G.; Salas, A.; Heyn, H.; Martelotto, L. G.

10.1101/2023.06.16.545221 — bioinformatics — Posted on 2023-06-19

1893 Specification and survival of post-metamorphic branchiomeric neurons in the hindbrain of a non-vertebrate chordate.

Gigante, E. D.; Piekarz, K. M.; Gurgis, A.; Cohen, L.; Razy-Krajka, F.; Popsuj, S.; Ali, H. S.; Mohana Sundaram, S.; Stolfi, A.

10.1101/2023.06.16.545305 — developmental biology — Posted on 2023-06-18

1894 DNA conserved across animals that controls genes for embryonic development

Frith, M. C.; Ni, S.

10.1101/2023.06.18.545459 — developmental biology — Posted on 2023-06-18

1895 Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

Nakonechnaya, T. O.; Moltedo, B.; Putintseva, E. V.; Leyn, S.; Bolotin, D. A.; Britanova, O. V.; Shugay, M.; Chudakov, D. M.

10.1101/2023.06.15.544726 — immunology — Posted on 2023-06-19

1896 Optimizing the Benefits of Mental Practice on Motor Acquisition and Consolidation with Moderate-Intensity Aerobic Exercise

Rannaud Monany, D.; Lebon, F.; Papaxanthis, C.

10.1101/2022.11.12.516269 — neuroscience — Posted on 2023-06-19

1897 CA3 circuit model compressing sequential information in theta oscillation and replay

Kuroki, S.; Mizuseki, K.

10.1101/2023.05.24.542204 — neuroscience — Posted on 2023-06-19

1898 An oncogenic isoform of septin 9 promotes the formation of juxtanuclear invadopodia by reducing nuclear deformability

Okletey, J.; Angelis, D.; Jones, T. M.; Montagna, C.; Spiliotis, E. T.

10.1101/2023.06.18.545473 — cell biology — Posted on 2023-06-18

1899 Dysregulated alveolar epithelial maintenance in Hermansky-Pudlak syndrome pulmonary fibrosis

Wang, J. Y.; Michki, N. S.; Banaschewski, B. J.; Pan, R. C.; Zepp, J. A.; Frank, D. B.; Young, L. R.

10.1101/2023.06.17.545390 — cell biology — Posted on 2023-06-18

1900 A system for in vivo evaluation of protein ubiquitination dynamics using deubiquitinase-deficient strains.

Radmall, K. S.; Shukla, P. K.; Chandrasekharan, M.

10.1101/2023.06.18.545485 — molecular biology — Posted on 2023-06-18

1901 Identification of the FSH-RH, the other gonadotropin-releasing hormone

Uehara, S. K.; Nishiike, Y.; Maeda, K.; Karigo, T.; Kuraku, S.; Okubo, K.; Kanda, S.

10.1101/2023.05.26.542428 — neuroscience — Posted on 2023-06-18

1902 Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos

Fang, J.; Kang, B. G.; Kam, T.-I.; Behensky, A.; Rines, J.; Kang, H. C.; Dawson, V. L.; Dawson, T.

10.1101/2023.06.18.545460 — cell biology — Posted on 2023-06-18

1903 Cortical tension regulates Hippo signaling via Par-1-mediated Kibra degradation

Tokamov, S. A.; Buiter, S.; Ullyot, A.; Scepanovic, G.; Williams, A. M.; Fernandez-Gonzalez, R.; Horne-Badovinac, S.; Fehon, R. G.

10.1101/2023.06.18.545491 — cell biology — Posted on 2023-06-18

1904 HIV-1 resistance to islatravir/tenofovir combination therapy in wild-type or NRTI resistant strains of diverse HIV-1 subtypes

Cilento, M. A.; Wen, X.; Reeve, A. B.; Snyder, A.; Ukah, O.; Carrillo, C. M.; Smith, C. P.; Edwards, K.; Wahoski, C. C.; Kitzler, D. R.; Kodama, E. N.; Mitsuya, H.; Parniak, M.; Tedbury, P. R.; Sarafianos, S. G.

10.1101/2023.06.18.545484 — microbiology — Posted on 2023-06-18

1905 Protein subcellular relocalization and function of duplicated flagellar calcium binding protein genes in honey bee trypanosomatid parasite

Yuan, X.; Kadowaki, T.

10.1101/2023.06.17.545447 — microbiology — Posted on 2023-06-18

1906 Efficient methods for target gene manipulation in haematopoietic stem cell derived human neutrophils.

Ng, A. Y.; Fox, E.; Brelstaff, J.; Frontini, M.; Summers, C.

10.1101/2023.06.17.545406 — cell biology — Posted on 2023-06-18

1907 Actin Y53 Phosphorylation Regulates Somatic F-actin Radial Translocation to Promote Neuronal Polarization

Hong, S.; Meka, D. P.; Kobler, O.; Scharrenberg, R.; Friedrich, C. M.; Schwanke, B.; Richter, M.; Calderon de Anda, F.

10.1101/2023.06.17.545417 — cell biology — Posted on 2023-06-18

1908 Heat-evolved algal symbionts enhance bleaching tolerance of adult corals without trade-off against growth

Chan, W. Y.; Rudd, D.; Meyers, L.; Topa, S. H.; van Oppen, M.

10.1101/2023.06.17.545444 — microbiology — Posted on 2023-06-18

1909 The TOR signaling pathway regulates vegetative development, aflatoxin biosynthesis and pathogenicity in Aspergillus flavus

Li, G.; Cao, X.; Tumukunde, E.; Zeng, Q.; Wang, S.

10.1101/2023.06.18.545466 — microbiology — Posted on 2023-06-18

1910 The Transcriptomics Pain Signature Database

Jahangiri Esfahani, S.; Parisien, M.; surbey, c.; Diatchenko, L.

10.1101/2023.06.16.545337 — genetics — Posted on 2023-06-18

1911 DNA binding analysis of rare variants in homeodomains reveals novel homeodomain specificity-determining residues

Kock, K. H.; Kimes, P. K.; Gisselbrecht, S. S.; Inukai, S.; Phanor, S. K.; Anderson, J. L.; Ramakrishnan, G. L.; Lipper, C. H.; Song, D.; Kurland, J. V.; Rogers, J. M.; Jeong, R.; Blacklow, S.; Irizarry, R. A.; Bulyk, M. L.

10.1101/2023.06.16.545320 — genetics — Posted on 2023-06-18

1912 Non-cognate immunity proteins provide broader defenses against interbacterial effectors in microbial communities

Knecht, A.; Sirias, D.; Utter, D. R.; Gibbs, K. A.

10.1101/2023.06.18.545353 — microbiology — Posted on 2023-06-18

1913 Bio-based decontamination and detoxification of total petroleum hydrocarbon contaminated dredged sediments: perspectives to produce constructed technosols in the frame of the circular economy.

Becarelli, S.; Bernabei, G.; Siracusa, G.; Baderna, D.; Ruffini Castiglione, M.; De Simone, G.; Di Gregorio, S.

10.1101/2023.06.18.545458 — microbiology — Posted on 2023-06-18

1914 Regulation of coronavirus nsp15 cleavage specificity by RNA structure

Salukhe, I.; Choi, R.; Voorhis, W. V.; Barrett, L.; Hyde, J. L.

10.1101/2023.05.12.540483 — microbiology — Posted on 2023-06-18

1915 A functional single nucleotide polymorphism upstream of the collagen type III gene may contribute to catastrophic fracture risk in Thoroughbred horses.

Palomino Lago, E.; Baird, A.; Blott, S.; McPhail, R. E.; Ross, A. C.; Durward-Akhurst, S.; Guest, D.

10.1101/2023.06.16.545331 — genetics — Posted on 2023-06-18

1916 KAT6A mutations drive transcriptional dysregulation of cell cycle and Autism risk genes in an Arboleda-Tham Syndrome cerebral organoid model

Nava, A. A.; Jops, C. T.; Vuong, C. K.; Niles-Jensen, S.; Bondhus, L.; Ong, C. J.; de la Torre-Ubieta, L.; Gandal, M. J.; Arboleda, V. A.

10.1101/2023.06.17.545322 — genetics — Posted on 2023-06-18

1917 The influence of prenatal alcohol exposure and maternal diet on offspring DNA methylation: a cross-species study

Bestry, M.; Larcombe, A. N.; Kresoje, N.; Chivers, E. K.; Bakker, C.; Fitzpatrick, J. P.; Elliott, E. J.; Craig, J. M.; Muggli, E.; Halliday, J.; Hutchinson, D.; Buckberry, S.; Lister, R.; Symons, M.; Martino, D.

10.1101/2023.06.15.544516 — genetics — Posted on 2023-06-18

1918 A 3D printed plastic frame deeply impacts yeast cell growth

Molina-Menor, E.; Vidal-Verdu, A.; Gomis-Olcina, C.; Pereto, J.; Porcar, M.

10.1101/2023.06.16.545257 — microbiology — Posted on 2023-06-18

1919 Population ecology and potential biogeochemical impacts of ssDNA and dsDNA soil viruses along a permafrost thaw gradient

Trubl, G.; Roux, S.; Borton, M. A.; Varsani, A.; Li, Y.-F.; Sun, C.; Jang, H. B.; Woodcroft, B. J.; Tyson, G. W.; Wrighton, K. C.; Saleska, S. R.; Eloe-Fadrosh, E. A.; Sullivan, M. B.; Rich, V. I.

10.1101/2023.06.13.544858 — microbiology — Posted on 2023-06-18

1920 Surface temperatures are influenced by handling stress independently of glucocorticoid levels in wild king penguins

Lewden, A.; Ward, C.; Noiret, A.; Avril, S.; Abolivier, L.; Gerard, C.; Hammer, T. L.; Raymond, E.; Robin, J.-P.; Viblanc, V. A.; Bize, P.; STIER, A.

10.1101/2023.06.16.545254 — zoology — Posted on 2023-06-18

1921 Dynamic decomposition of transcriptome responses during plant effector-triggered immunity revealed conserved responses in two distinct cell populations

Liu, X.; Igarashi, D.; Hillmer, R. A.; Stoddard, T.; Lu, Y.; Tsuda, K.; Myers, C. L.; Katagiri, F.

10.1101/2022.12.30.522333 — systems biology — Posted on 2023-06-18

1922 Plant-derived, nodule-specific cysteine rich peptides inhibit growth and psyllid acquisition of 'Candidatus Liberibacter asiaticus', the citrus Huanglongbing bacterium

Higgins, S. A.; Igwe, D. O.; Ramsey, J. S.; DeBlasio, S. L.; Pitino, M.; Niedz, R.; Shatters, R. G.; Fleites, L.; Heck, M. L.

10.1101/2023.06.18.545457 — plant biology — Posted on 2023-06-18

1923 Phase-shifting mid-infrared optothermal microscopy for wide-field hyperspectral imaging of living cells

Yuan, T.; Riobo, L.; Gasparin, F.; Ntziachristos, V.; Pleitez, M. A.

10.1101/2023.06.17.545432 — bioengineering — Posted on 2023-06-18

1924 Synergistic genomic mechanisms of adaptation to ocean acidification in a coral holobiont

Leiva, C.; Perez-Portela, R.; Lemer, S.

10.1101/2023.06.18.545179 — evolutionary biology — Posted on 2023-06-18

1925 Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

Mukherjee, R.; Hoffmann, M.; Gonzalez, A.; Bhattacharya, A.; Kuncha, S. K.; Rathore, R.; Shin, D.; Colby, T.; Matic, I.; Misra, M.; Dikic, I.

10.1101/2023.06.17.545420 — cell biology — Posted on 2023-06-18

1926 Epitope spreading of Lyme autoantigen apoB-100 and CD4+ T cell responses to Borrelia burgdorferi Mcp4 are regulated by IL-10 in murine Lyme disease

Danner, R.; Pereckas, M.; Rouse, J. R.; Wahhab, A.; Prochniak, L. M.; Lochhead, R. B.

10.1101/2023.06.16.545225 — immunology — Posted on 2023-06-18

1927 Non-coding sequence variation reveals fragility within interleukin 2 feedback circuitry and shapes autoimmune disease risk

Simeonov, D. R.; Park, K.; Cortez, J. T.; Young, A.; Li, Z.; Nguyen, V.; Umhoefer, J.; Indart, A. C.; Woo, J.; Anderson, M. S.; Tsang, J. S.; Germain, R. N.; Wong, H. S.; Marson, A.

10.1101/2023.06.17.545426 — immunology — Posted on 2023-06-18

1928 R2R3-MYB EVER links emission of volatiles with epicuticular wax biosynthesis in petunia petal epidermis

Skaliter, O.; Bednarczyk, D.; Shor, E.; Shklarman, E.; Manasherova, E.; Aravena-Calvo, J.; Kerzner, S.; Cna'ani, A.; Jasinska, W.; Masci, T.; Dvir, G.; Edelbaum, O.; Rimon, B.; Brotman, Y.; Cohen, H.; Vainstein, A.

10.1101/2023.06.15.545203 — plant biology — Posted on 2023-06-18

1929 A systematic review of the diversity and virulence correlates of metastrongyle lungworms in marine mammals

Fischbach, J. R.; Seguel, M. A.

10.1101/2023.02.03.527020 — pathology — Posted on 2023-06-18

1930 Tracing the substrate translocation mechanism in P-glycoprotein

Gewering, T.; Waghray, D.; Parey, K.; Jung, H.; Tran, N. N. B.; Zapata, J.; Zhao, P.; Chen, H.; Januliene, D.; Hummer, G.; Urbatsch, I. L.; Moeller, A.; Zhang, Q.

10.1101/2022.04.28.489897 — biophysics — Posted on 2023-06-18

1931 Image-based Flow Simulation of Platelet Aggregates under Different Shear Rates

Hao, Y.; Zavodszky, G.; Tersteeg, C.; Barzegari, M.; Hoekstra, A. G.

10.1101/2023.02.22.529480 — biophysics — Posted on 2023-06-18

1932 Multiplexed and millimeter-scale fluorescence nanoscopy of cells and tissue sections via prism-illumination and microfluidics-enhanced DNA-PAINT

Rames, M. J.; Kenison, J.; Heineck, D.; Civitci, F.; Szczepaniak, M.; Zheng, T.; Shangguan, J.; Zhang, Y.; Esener, S.; Nan, X.

10.1101/2022.08.07.503091 — biophysics — Posted on 2023-06-18

1933 Structural study of membrane proteins using vesicles

Liu, H.; Dang, S.

10.1101/2023.06.17.545446 — biophysics — Posted on 2023-06-18

1934 A combined computational-biochemical approach offers an accelerated path to membrane protein solubilization

Pierce, M. R.; Ji, J.; Novak, S. X.; Sieburg, M. A.; Nangia, S.; Hougland, J. L.

10.1101/2023.06.18.545468 — biochemistry — Posted on 2023-06-18

1935 Enzyme-mediated alkynylation enables transcriptome-wide identification of pseudouridine modifications

Wang, Y.; Zhang, L.; Zhang, W.; Gao, B.; Ye, C.; Dai, Q.; Wang, K.; Luo, M.; Pan, T.; He, C.

10.1101/2023.06.18.545436 — biochemistry — Posted on 2023-06-18

1936 The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs

Murray, G. G. R.; Hossain, A. S. M. M.; Miller, E.; Bruchmann, S.; Balmer, A. J.; Matuszewska, M.; Herbert, J.; Hadjirin, N. F.; Mugabi, R.; Li, G.; Ferrando, M. L.; Fernades de Oliveira, I. M.; Nguyen, T.; Yen, P. L. K.; Moe, A. Z.; Wai, T. S.; Gottschalk, M.; Aragon, V.; Valentin-Weigand, P.; Heegaard, P. M. H.; Vrieling, M.; Maw, M. T.; Myint, H. T.; Win, Y. T.; Hoa, N. T.; Bentley, S. D.; Clavijo, M. J.; Wells, J. M.; Tucker, A. W.; Weinert, L. A.

10.1101/2023.05.17.540811 — evolutionary biology — Posted on 2023-06-18

1937 A multi-stage, delay differential model of snow crab population dynamics in the Scotian Shelf of Atlantic Canada

Choi, J. S.

10.1101/2023.02.13.528296 — ecology — Posted on 2023-06-18

1938 An integrative multi-omics approach to draft gene regulatory networks at a cell type resolution

Voronov, D.; Paganos, P.; Magri, M. S.; Cuomo, C.; Maeso, I.; Gomez-Skarmeta, J. L.; Arnone, M. I.

10.1101/2023.05.12.540495 — developmental biology — Posted on 2023-06-18

1939 Brain fingerprinting using EEG graph inference

Miri, M.; Abootalebi, V.; Amico, E.; Saeedi-Sourck, H.; Van De Ville, D.; Behjat, H.

10.1101/2023.03.11.532201 — neuroscience — Posted on 2023-06-18

1940 Dlg5 and Cadherins are key to peripheral glia integrity

Das, M.; Cheng, D.; Matzat, T.; Auld, V.

10.1101/2022.11.01.514384 — neuroscience — Posted on 2023-06-18

1941 Tracking the behavioral and neural dynamics of semantic representations through negation

Zuanazzi, A.; Ripolles, P.; Lin, W. M.; Gwilliams, L.; King, J.-R.; Poeppel, D.

10.1101/2022.10.14.512299 — neuroscience — Posted on 2023-06-18

1942 The Plasminogen-Apple-Nematode (PAN) domain suppresses JA/ET defense pathways in plants

De, K.; Pal, D.; Shanks, C. M.; Yates, T. B.; Feng, K.; Jawdy, S.; Hassan, M. M.; Prabhakar, P. K.; Yang, J.-Y.; Chapla, D.; Moremen, K. W.; Urbanowicz, B.; Muchero, W.; Binder, B.

10.1101/2023.06.15.545202 — plant biology — Posted on 2023-06-18

1943 Histone binding of ASF1 is required for fruiting body development, but not for genome stability in the filamentous fungus Sordaria macrospora

Breuer, J.; Busche, T.; Kalinowski, J.; Nowrousian, M.

10.1101/2023.06.16.545311 — molecular biology — Posted on 2023-06-18

1944 A MICROGLIAL ACTIVITY STATE BIOMARKER PANEL DIFFERENTIATES FTD-GRANULIN AND AD FROM CONTROL CASES

Pesämaa, I.; Mueller, S. A.; Robinson, S.; Darcher, A.; Paquet, D.; Zetterberg, H.; Lichtenthaler, S. F.; Haass, C.

10.1101/2023.06.15.545187 — neuroscience — Posted on 2023-06-18

1945 Demographic Reconstruction of the Western Sheep Expansion from Whole-Genome sequences

Morell Miranda, P.; Soares, A. E.; Günther, T.

10.1101/2023.06.16.545369 — genomics — Posted on 2023-06-18

1946 The influence of prenatal alcohol exposure and maternal diet on offspring DNA methylation: a cross-species study

10.1101/2023.06.15.544516 — genetics — Posted on 2023-06-18

1947 Disruption of maternal ACKR3 has profound effects on embryos and offspring.

Fukuoka, A.; Wilson, G. J.; Pitmon, E.; Koumbas Foley, L.; Johnssen, H.; Pingen, M.; Graham, G.

10.1101/2023.06.15.545186 — developmental biology — Posted on 2023-06-18

1948 Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness

Amir Arastehfar, A.; Daneshnia, F.; Hovhannisyan, H.; Fuentes, D.; Cabrera, N.; Quinteros, C.; Ilkit, M.; Ünal, N.; Hilmioglu-Polat, S.; Jabeen, K.; Zaka, S.; Desai, J. V.; Lass-Flörl, C.; Shor, E.; Gabaldon, T.; Perlin, D. S.

10.1101/2023.06.15.545195 — microbiology — Posted on 2023-06-18

1949 Trait salivary alpha-amylase activity levels define the conditions for facilitation by L-DOPA of extinction consolidation

Andres, E.; Chuan-Peng, H.; Gerlicher, A. M. V.; Meyer, B.; Tuescher, O.; Kalisch, R.

10.1101/2022.11.12.516261 — neuroscience — Posted on 2023-06-18

1950 Single-cell sequencing of tumor-associated macrophages in a Drosophila model.

Khalili, D.; Mohammed, M.; Kunc, M.; Ankarklev, J.; Theopold, U.

10.1101/2023.06.17.545411 — cancer biology — Posted on 2023-06-18

1951 BATCH-SCAMPP: Scaling phylogenetic placement methods to place many sequences

Wedell, E.; Shen, C.; Warnow, T.

10.1101/2022.10.26.513936 — bioinformatics — Posted on 2023-06-18

1952 CapTrap-Seq: A platform-agnostic and quantitative approach for high-fidelity full-length RNA transcript sequencing

Carbonell-Sala, S.; Lagarde, J.; Nishiyori, H.; Palumbo, E.; Arnan, C.; Takahashi, H.; Carninci, P.; Uszczynska-Ratajczak, B.; Guigo, R.

10.1101/2023.06.16.543444 — genomics — Posted on 2023-06-18

1953 Fluctuating selection facilitates the discovery of broadly effective but difficult to reach adaptive outcomes in yeast

Fasanello, V. J.; Liu, P.; Fay, J. C.; Botero, C. A.

10.1101/2023.06.17.545402 — evolutionary biology — Posted on 2023-06-18

1954 Features that Govern Terminator Strength in Plants

Gorjifard, S.; Jores, T.; Tonnies, J.; Mueth, N. A.; Bubb, K. L.; Wrightsman, T.; Buckler, E. S.; Fields, S.; Cuperus, J. T.; Queitsch, C.

10.1101/2023.06.16.545379 — plant biology — Posted on 2023-06-18

1955 TooManyCellsInteractive: a visualization tool for dynamic exploration of single-cell data

Klamann, C.; Lau, C.; Schwartz, G. W.

10.1101/2023.06.16.544954 — bioinformatics — Posted on 2023-06-18

1956 NMFClustering: Accessible NMF-based clustering utilizing GPU acceleration

Liefeld, T.; Huang, E.; Wenzel, A. T.; Yoshimoto, K.; Sharma, A. K.; Sicklick, J. K.; Mesirov, J. P.; Reich, M. M.

10.1101/2023.06.16.545370 — bioinformatics — Posted on 2023-06-18

1957 Carbon oxidation with sacrificial anodes to inhibit O2 evolution in membrane-less bioelectrochemical systems for microbial electrosynthesis

Rohbohm, N.; Sun, T.; Blasco-Gomez, R.; Byrne, J. M.; Kappler, A.; Angenent, L. T.

10.1101/2022.08.23.504965 — bioengineering — Posted on 2023-06-18

1958 The AusTraits Plant Dictionary

Wenk, E. H.; Sauquet, H.; Gallagher, R. V.; Brownlee, R.; Boettiger, C.; Coleman, D.; Yang, S.; Auld, T.; Barrett, R. L.; Brodribb, T.; Choat, B.; Dun, L.; Ellsworth, D.; Gosper, C.; Guja, L.; Jordan, G. J.; Breton, T.; Leigh, A.; Irving, P.; Medlyn, B.; Nolan, R.; Ooi, M.; Sommerville, K. D.; Vesk, P.; White, M.; Wright, I. J.; Falster, D. S.

10.1101/2023.06.16.545047 — ecology — Posted on 2023-06-18

1959 Nyctinastic leaf folding mimic reduces herbivory by Chromacris trogon grasshoppers (Orthoptera:Romaleidae)

Bell, A. B.

10.1101/2023.06.16.545391 — ecology — Posted on 2023-06-18

1960 When offspring outsmarting parents: Neuronal genes expression in two generations of marine parasitic worm

Tolstenkov, O.; Chatzigeorgiou, M.; Gorbushin, A.

10.1101/2023.06.17.545403 — zoology — Posted on 2023-06-18

1961 Genome-wide, Organ-delimited gene regulatory networks (OD-GRNs) provide high accuracy in candidate TF selection across diverse processes.

Ranjan, R.; Srijan, S.; Balekuttira, S.; Agarwal, T.; Dobbins, M.; Wang, X.; Hudson, K.; Li, Y.; Varala, K.

10.1101/2023.06.17.542927 — plant biology — Posted on 2023-06-18

1962 RAMAN DEVELOPMENTAL MARKERS IN ROOT CELL WALLS ARE ASSOCIATED WITH LODGING TENDENCY IN TEF

Diehn, S.; Kirby, N.; Ben-Zeev, S.; Alemu, M. D.; Saranga, Y.; Elbaum, R.

10.1101/2023.06.16.545357 — plant biology — Posted on 2023-06-18

1963 Dual effects of the small-conductance Ca2+-activated K+ current on human atrial electrophysiology and Ca2+-driven arrhythmogenesis: an in silico study

Herrera, N. T.; Zhang, X.; Ni, H.; Maleckar, M. M.; Heijman, J.; Dobrev, D.; Grandi, E.; Morotti, S.

10.1101/2023.06.16.545367 — physiology — Posted on 2023-06-18

1964 Proteins containing 6-crossing knot types andtheir folding pathways

Sikora, M.; Flapan, E.; Wong, H.; Rubach, P.; Garstka, W.; Niewieczerzal, S.; Rawdon, E. J.; Sulkowska, J. I.

10.1101/2023.06.16.545156 — biophysics — Posted on 2023-06-18

1965 Unbiased single-cell morphology with self-supervised vision transformers

Doron, M.; Moutakanni, T.; Chen, Z. S.; Moshkov, N.; Caron, M.; Touvron, H.; Bojanowski, P.; Pernice, W. M.; Caicedo, J. C.

10.1101/2023.06.16.545359 — bioinformatics — Posted on 2023-06-18

1966 A Two-Filter Adaptation to Achieve Hemodiafiltration with Enhanced Performance

Chu, K.; Li, P.; Ausri, I.; Vasconez, C.; Tang, X.

10.1101/2023.06.16.545389 — bioengineering — Posted on 2023-06-18

1967 Collective pooling of foraging information in animal fission-fusion dynamics

Ramos-Fernandez, G.; Smith Aguilar, S. E.

10.1101/2023.06.16.545019 — animal behavior and cognition — Posted on 2023-06-18

1968 Anthropogenic nest material use correlates with human landscape modifications in a global sample of birds

Sheard, C.; Stott, L.; Street, S. E.; Healy, S. D.; Sugasawa, S.; Lala, K. N.

10.1101/2023.06.16.545374 — evolutionary biology — Posted on 2023-06-18

1969 The phoretic mite (Arachnida: Acari) assemblage of the Douglas-fir beetle, Dendroctonus pseudotsugae Hopkins (Coleoptera: Curculionidae)

Browning, L.-A.; Huber, D. P. W.

10.1101/2023.06.16.545383 — ecology — Posted on 2023-06-18

1970 An Experimental Platform for Stochastic Analyses of Single Serotonergic Fibers in the Mouse Brain

Mays, K. C.; Haiman, J. H.; Janusonis, S.

10.1101/2023.06.16.545362 — neuroscience — Posted on 2023-06-18

1971 Small RNAs from fungal pathogen Botrytis cinerea ride in extracellular vesicles to enter plant cells through clathrin-mediated endocytosis

He, B.; Wang, H.; Liu, G.; Chen, A.; Cai, Q.; Jin, H.

10.1101/2023.06.15.545159 — plant biology — Posted on 2023-06-18

1972 Characterization of human lightness discrimination thresholds for independent spectral variations

Reynolds, D. J.; Singh, V.

10.1101/2023.06.16.545355 — animal behavior and cognition — Posted on 2023-06-18

1973 ATP10A promotes endothelial cell insulin sensitivity and protects against diet-induced dyslipidemia in female mice

Norris, A. C.; Yazlovitskaya, E. M.; Zhu, L.; Rose, B. S.; Mansueto, A.; Gibson-Corley, K. N.; May, J. C.; McLean, J. A.; Stafford, J. M.; Graham, T. R.

10.1101/2023.06.16.545392 — molecular biology — Posted on 2023-06-17

1974 Proteasome-dependent degradation of histone H1 subtypes is mediated by its C-terminal domain.

Garcia-Gomis, D. R.; Lopez-Gomez, J.; Andres, M. R.; Ponte, I.; Roque, A.

10.1101/2023.06.17.545431 — molecular biology — Posted on 2023-06-18

1975 Hypervirulent pneumococci display high levels of nasopharyngeal shedding and rapid onward transmission

Baltazar, M.; Audshasai, T.; Jacques, L. C.; Yang, M.; Kadioglu, A.

10.1101/2023.06.17.545125 — microbiology — Posted on 2023-06-17

1976 Genomic characterization of the C. tuberculostearicum species complex, a ubiquitous member of the human skin microbiome

Ahmed, N.; Joglekar, P.; Deming, C.; NISC Comparative Sequencing Program, ; Lemon, K. P.; Kong, H. H.; Segre, J. A.; Conlan, S.

10.1101/2023.06.16.545375 — microbiology — Posted on 2023-06-17

1977 Characterization of novel fungal-algal symbiosis on LDPE plastic surfaces in the Mediterranean Sea

Itzhari, S. S.; Davidov, K.; Oren, M.

10.1101/2023.06.17.545398 — microbiology — Posted on 2023-06-17

1978 The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates biofilm formation and oral commensalism

Glazier, V. E.; Kamara, J.; Ollinger, T.; Solis, N. V.; Zarnowski, R.; Wakade, R. S.; Kim, M.-j.; Weigel, G. J.; Liang, S.-H.; Bennett, R. J.; Wellington, M.; Andes, D. R.; Stamnes, M.; Filler, S. G.; Krysan, D. J.

10.1101/2023.06.17.545405 — microbiology — Posted on 2023-06-17

1979 Unveiling consistency in flexibility: the role of reward and cognitive control in moral decisions

Xu, X. J.; Yang, G.; Huang, J.; Wang, R.; Wu, H.

10.1101/2023.06.17.545416 — neuroscience — Posted on 2023-06-17

1980 Cortical Surface Area Relates to Distinct Computational Properties in Human Visual Perception

Murray, S. O.; Kolodny, T.; Webb, S. J.

10.1101/2023.06.16.545373 — neuroscience — Posted on 2023-06-17

1981 Characteristic differences in tibial subchondral bone changes in the post-traumatic knee osteoarthritis model

Arakawa, K.; Takahata, K.; Usami, Y.; Kokubun, T.

10.1101/2023.02.27.530166 — pathology — Posted on 2023-06-18

1982 Context-specific GITR agonism potentiates anti-PD-L1 and CD40-based immuno- chemotherapy combination in heterogeneous pancreatic tumors

Ragulan, C.; Desai, K.; Lawrence, P. V.; Ikami, Y.; Aalam, M. M.; Ps, H.; Kannan, N.; Cunningham, D.; Starling, N.; Sadanandam, A.

10.1101/2023.06.16.545301 — cancer biology — Posted on 2023-06-18

1983 Systems engineering of Saccharomyces cerevisiae for synthesis and accumulation of vanillin

Mo, Q.; Yuan, J.

10.1101/2023.06.16.545388 — bioengineering — Posted on 2023-06-18

1984 Formalin fixation and paraffin embedding interfere with preservation of optical metabolic assessments based on endogenous NAD(P)H and FAD two photon excited fluorescence

Sanchez-Hernandez, A.; Polleys, C. M.; Georgakoudi, I.

10.1101/2023.06.16.545363 — bioengineering — Posted on 2023-06-18

1985 Hierarchical design of pseudosymmetric protein nanoparticles

Dowling, Q.; Park, Y.-J.; Gerstenmaier, N.; Yang, E.; Wargacki, A.; Hsia, Y.; Fries, C.; Ravichandran, R.; Walkey, C.; Burrell, A.; Veesler, D.; Baker, D.; King, N.

10.1101/2023.06.16.545393 — bioengineering — Posted on 2023-06-18

1986 Simultaneous assessment of human genome and methylome data in a single experiment using limited deamination of methylated cytosine.

Yan, B.; Wang, D.; Ettwiller, L.

10.1101/2023.06.16.545253 — genomics — Posted on 2023-06-17

1987 GENE EXPRESSION WITHIN A HUMAN CHOROIDAL NEOVASCULAR MEMBRANE USING SPATIAL TRANSCRIPTOMICS

Voigt, A. P.; Mullin, N. K.; Navratil, E. M.; Flamme-Wiese, M. J.; Lin, L.-C.; Scheetz, T. E.; Han, I. C.; Stone, E. M.; Tucker, B. A.; Mullins, R. F.

10.1101/2023.06.16.544770 — genomics — Posted on 2023-06-17

1988 Forecasting histone methylation by Polycomb complexes with minute-scale precision

Lundkvist, M. J.; Lizana, L.; Schwartz, Y. B.

10.1101/2023.06.16.545270 — developmental biology — Posted on 2023-06-17

1989 Neuronal modeling of magnetoencephalography responses in auditory cortex to auditory and visual stimuli

Lankinen, K.; Ahveninen, J.; Jas, M.; Raij, T.; Ahlfors, S. P.

10.1101/2023.06.16.545371 — neuroscience — Posted on 2023-06-17

1990 Neuronal lineage tracing from progenitors in human cortical organoids reveals novel mechanisms of human neuronal production, diversity, and disease

Bury, L. A. D.; Fu, S.; Wynshaw-Boris, A.

10.1101/2023.06.17.545314 — neuroscience — Posted on 2023-06-17

1991 Changes in ADAR RNA Editing Patterns in CMV and ZIKV Congenital Infections

Wales-McGrath, B.; Mercer, H. M.; Piontkivska, H.

10.1101/2023.06.16.545385 — bioinformatics — Posted on 2023-06-17

1992 QRS Detection by Rules Based Multiple Channel Combinatorial Optimization

Hopenfeld, B.

10.1101/2023.06.16.545354 — bioengineering — Posted on 2023-06-17

1993 The mitochondrial calcium uniporter transports Ca2+ via a ligand-relay mechanism.

Chan, C.; Yuan, C.-C.; McCoy, J. G.; Ward, P. S.; Grabarek, Z.

10.1101/2023.06.17.545435 — biochemistry — Posted on 2023-06-17

1994 Enantioselectivity in the Enzymatic Dehydration of Malate and Tartrate: Mirror Image Specificities of Structurally Similar Dehydratases

Bellur, A.; Mukherjee, S.; Sharma, P.; Jayaraman, V.; Balaram, H.

10.1101/2023.06.17.545066 — biochemistry — Posted on 2023-06-17

1995 xpanding the toolkit for genetic manipulation and discovery in Candida species using a CRISPR ribonucleoprotein-based approach

Gregor, J. B.; Gutierrez-Schultz, V. A.; Hoda, S.; Baker, K. M.; Saha, D.; Burghaze, M. G.; Briggs, S. D.

10.1101/2023.06.16.545382 — genetics — Posted on 2023-06-17

1996 The Janelia Atalanta plasmids provide a simple and efficient CRISPR/Cas9-mediated homology directed repair platform for Drosophila

Stern, D. L.; Kim, E.; Berhman, E. L.

10.1101/2023.06.17.545412 — genetics — Posted on 2023-06-17

1997 Effects of dopamine and opioid receptor antagonism on the neural processing of social and non-social rewards

Massaccesi, C.; Korb, S.; Götzendorfer, S.; Chiappini, E.; Willeit, M.; Lundström, J. N.; Windischberger, C.; Eisenegger, C.; Silani, G.

10.1101/2023.06.16.545306 — neuroscience — Posted on 2023-06-17

1998 Cellular Iron Deficiency Disrupts Thyroid Hormone Regulated Gene Expression in Developing Hippocampal Neurons

Monko, T. R.; Tripp, E. H.; Burr, S. E.; Gunderson, K. N.; Lanier, L. M.; Georgieff, M. K.; Bastian, T. W.

10.1101/2023.06.17.545408 — neuroscience — Posted on 2023-06-17

1999 Transcriptome of left ventricle and sinoatrial node in young and old C57 mice

Qu, J.-H.; Tarasov, K. V.; Tarasova, Y. S.; Lakatta, E. G.

10.1101/2023.06.16.545319 — systems biology — Posted on 2023-06-17

2000 Cryo-EM studies of the four E. coli paralogs establish ABCF proteins as master plumbers of the peptidyl-transferase center of the ribosome

Singh, S.; Gentry, R. C.; Fu, Z.; Bailey, N. A.; Altomare, C. G.; Wong, K.-H.; Neky, M. J.; Wang, C.; Ray, K. K.; Chi, Y.-C.; Zhang, Z.; Grassucci, R. A.; Frank, J.; Boël, G.; Gonzalez, R. L.; Hunt, J. F.

10.1101/2023.06.15.543498 — biophysics — Posted on 2023-06-17

2001 Confined environment facilitates stacked conformations in Holliday Junction

Agarwal, P.; Kabir, S. H.; Pal, N.

10.1101/2023.06.17.545413 — biophysics — Posted on 2023-06-17

2002 Design of four component T=4 tetrahedral, octahedral, and icosahedral protein nanocages through programmed symmetry breaking

Lee, S.; Kibler, R. D.; Hsia, Y.; Borst, A. J.; Philomin, A.; Kennedy, M. A.; Stoddard, B. L.; Baker, D.

10.1101/2023.06.16.545341 — biochemistry — Posted on 2023-06-17

2003 Self-assembly of Grb2 meshworks revealed by Grb2-Gab1497-528 complex structure

Breithaupt, C.; Gruber, T.; Mandel, K.; Lewitzky, M.; Meister, A.; Jochen, B.; Feller, S. M.; Stubbs, M. T.

10.1101/2023.06.17.545433 — biochemistry — Posted on 2023-06-17

2004 THUMPD2 catalyzes N2-methylation on the spliceosome catalytic center of U6 snRNA and regulates pre-mRNA splicing

Yang, W.-Q.; Ge, J.-Y.; Zhang, X.-F.; Lin, L.; Zhu, W.-Y.; Shi, Y.-G.; Xu, B.; Liu, R.-J.

10.1101/2023.06.17.545410 — biochemistry — Posted on 2023-06-17

2005 Transcriptome data from silica-preserved leaf tissue reveals gene flow patterns in a Caribbean bromeliad

Ruiz-Vargas, N.; Ramanauskas, K.; Tyszka, A. S.; Mason-Gamer, R. J.; Walker, J. F.

10.1101/2023.06.16.545126 — evolutionary biology — Posted on 2023-06-17

2006 Development and deployment of improved Anopheles gambiae s.l. field surveillance by adaptive spatial sampling design

Monteiro, G. M.; Djogbenou, L. S.; Donnelly, M. J.; Sedda, L.

10.1101/2023.06.16.545360 — ecology — Posted on 2023-06-17

2007 Diversification of Nucleoside Analogues as Potent Antiviral Drug Leads

Scheeff, S.; Wang, Y.; Lyu, M.-Y.; Nasiri Ahmadabadi, B.; Hau, S. C. K.; Hui, T. K. C.; Zhang, Y.; Zuo, Z.; Chan, R. W. Y.; Ng, B. W.-L.

10.1101/2023.06.17.545395 — microbiology — Posted on 2023-06-17

2008 PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

Kerr, C. M.; Parthasarathy, S.; Schwarting, N.; O'Connor, J. J.; Giri, E.; More, S.; Orozco, R. C.; Fehr, A. R.

10.1101/2023.06.16.545351 — microbiology — Posted on 2023-06-17

2009 Extracting nanoscale membrane morphology fromsingle-molecule localizations

Marin, Z.; Fuentes, L. A.; Bewersdorf, J.; Baddeley, D.

10.1101/2023.01.26.525798 — biophysics — Posted on 2023-06-17

2010 Metal Ions and their Effects on Antimicrobial Resistance Development in Wastewater

Sutradhar, I.; Kalyan, P.; Chukwu, K.; Abia, A. L. K.; Mbanga, J.; Hamer, D. H.; Essack, S.; Zaman, M. H.

10.1101/2023.06.16.545339 — bioengineering — Posted on 2023-06-17

2011 Lost in the WASH. The functional human WASH complex 1 gene is on chromosome 20

Cerdan-Velez, D.; Tress, M. L.

10.1101/2023.06.14.544951 — molecular biology — Posted on 2023-06-17

2012 A novel SATB1 protein isoform with different biophysical properties

Zelenka, T.; Papamatheakis, D.-A.; Tzerpos, P.; Panagopoulos, G.; Tsolis, K. C.; Papadakis, V. M.; Mariatos Metaxas, D.; Papadogkonas, G.; Mores, E.; Kapsetaki, M.; Papamatheakis, J.; Stanek, D.; Spilianakis, C.

10.1101/2021.08.11.455932 — molecular biology — Posted on 2023-06-17

2013 Microdiversity of the Vaginal Microbiome is Associated with Preterm Birth

Liao, J.; Shenhav, L.; Urban, J. A.; Serrano, M.; Zhu, B.; Buck, G. A.; Korem, T.

10.1101/2023.01.13.523991 — microbiology — Posted on 2023-06-17

2014 Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to investigate the sensitivity and costimulatory requirements of TCRs and CARs

Patel, A.; Andre, V.; Bustamante Eguiguren, S.; Barton, M. I.; Denham, E. M.; Pettmann, J.; Morch, A. M.; Kutuzov, M.; Siller-Farfan, J. A.; Dustin, M. L.; van der Merwe, P. A.; Dushek, O.

10.1101/2023.06.15.545075 — immunology — Posted on 2023-06-17

2015 Dynamics of cortical contrast adaptation predict perception of signals in noise.

Angeloni, C. F.; Mlynarski, W.; Piasini, E.; Williams, A. M.; Wood, K. C.; Garami, L.; Hermundstad, A.; Geffen, M. N.

10.1101/2021.08.11.455845 — neuroscience — Posted on 2023-06-17

2016 Atypical speech production of multisyllabic words and phrases by children with developmental dyslexia

Keshavarzi, M.; M. Di Liberto, G.; Gabrielczyk, F.; Wilson, A.; Macfarlane, A.; Goswami, U.

10.1101/2022.08.24.505144 — neuroscience — Posted on 2023-06-17

2017 Whole genome sequencing reveals autooctoploidy in the Chinese sturgeon and its evolutionary trajectories

Wang, B.; Wu, B.; Liu, X.; Hu, Y.; Ming, Y.; Bai, M.; Liu, J.; Xiao, K.; Zeng, Q.; Yang, J.; Wang, H.; Guo, B.; Tan, C.; Hu, Z.; Zhao, X.; Li, Y.; Yue, Z.; Mei, J.; Jiang, W.; Yang, Y.; Li, Z.; Gao, Y.; Chen, L.; Jian, J.; Du, H.

10.1101/2023.06.06.543648 — genomics — Posted on 2023-06-17

2018 A flexible empirical Bayes approach to multivariate multiple regression, and its improved accuracy in predicting multi-tissue gene expression from genotypes

Morgante, F.; Carbonetto, P.; Wang, G.; Zou, Y.; Sarkar, A.; Stephens, M.

10.1101/2022.11.22.517471 — genetics — Posted on 2023-06-17

2019 Scalable covariance-based connectivity inference for synchronous neuronal networks

Kim, T.; Chen, D.; Hornauer, P.; Kumar, S. S.; Schröter, M.; Borgwardt, K.; Hierlemann, A.

10.1101/2023.06.17.545399 — neuroscience — Posted on 2023-06-17

2020 CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

10.1101/2023.06.16.545386 — cell biology — Posted on 2023-06-17

2021 PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration

Holt, J. R.; Chen, J.; Evans, E. L.; Lowengrub, J. S.; Pathak, M. M.

10.1101/2022.10.13.512181 — biophysics — Posted on 2023-06-17

2022 Embryonic origins of bipotent endothelial-macrophage progenitor cells in postnatal aorta

Williamson, A. E.; Liyanage, S.; Hassanshahi, M.; Dona, M. S. I.; Toledo-Flores, D.; Tran, D. X. A.; Dimasi, C.; Schwarz, N.; Fernando, S.; Salagaras, T.; Long, A.; Kazenwadel, J.; Harvey, N. L.; Drummond, G. R.; Vinh, A.; Chandrakanthan, V.; Misra, A.; Neufeld, Z.; Tan, J. T. M.; Martelotto, L. G.; Polo, J. M.; Bonder, C. S.; Pinto, A. R.; Sharma, S.; Nicholls, S. J.; Bursill, C. A.; Psaltis, P. J.

10.1101/2021.10.18.464001 — cell biology — Posted on 2023-06-17

2023 The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor

Johnson, T. A.; Fettweis, G.; Wagh, K.; Almeida-Prieto, B.; Krishnamurthy, M.; Upadhyaya, A.; Hager, G. L.; Alvarez de la Rosa, D.

10.1101/2023.01.26.525745 — molecular biology — Posted on 2023-06-17

2024 Mitochondrial genomes of Pleistocene megafauna retrieved from recent sediment layers of two Siberian lakes

Seeber, P. A.; Batke, L.; Dvornikiv, Y.; Schmidt, A. A.; Wang, Y.; Stoof-Leichsenring, K.; Moon, K.; Shapiro, B.; Epp, L.

10.1101/2023.06.16.545324 — molecular biology — Posted on 2023-06-16

2025 Inhibition of Notch activity by phosphorylation of CSL in response to parasitization in Drosophila

Deichsel, S.; Frankenreiter, L.; Fechner, J.; Gahr, B. M.; Zimmermann, M.; Mastel, H.; Preis, I.; Preiss, A.; Nagel, A. C.

10.1101/2023.06.16.545247 — developmental biology — Posted on 2023-06-17

2026 Role of BicDR in bristle shaft construction, tracheal development, and support of BicD functions

Jejina, A.; Ayala, Y.; Hernandez, G.; Suter, B.

10.1101/2023.06.16.545245 — cell biology — Posted on 2023-06-16

2027 Corepressor inactivation through tandem linear motif-induced polymerization

10.1101/2023.06.16.545227 — molecular biology — Posted on 2023-06-16

2028 Ionizing radiation responses are incidental to desiccation responses in the bdelloid rotifer Adineta vaga

Moris, V. C.; Bruneau, L.; Berthe, J.; Heuskin, A.-C.; Penninckx, S.; Ritter, S.; Weber, U.; Durante, M.; Danchin, E. G. J.; Hespeels, B.; Van Doninck, K.

10.1101/2023.06.16.545282 — molecular biology — Posted on 2023-06-16

2029 VAMP2 regulates phase separation of alpha-synuclein

Agarwal, A.; Raza, F.; Hilcenko, C.; Stott, K.; Morone, N.; Warren, A. J.; Lautenschlaeger, J.

10.1101/2023.06.16.545277 — cell biology — Posted on 2023-06-16

2030 Spatiotemporal cell landscape of human embryonic tooth development

Shi, Y.; Sun, S.; Li, J.; Wang, S.; Yu, Y.; Guo, K.; Yang, J.; Han, L.; Wei, W.; Qiu, J.

10.1101/2023.03.01.530693 — cell biology — Posted on 2023-06-16

2031 The G-alpha Gpa1 directs septin localization in the mating projection of Saccharomyces cerevisiae through its Ubiquitination Domain and Endocytic Machinery

Johnson, C. P.; Hart, A.; Jarvis, K. F.; Latario, S. G.; Shrestha, S.; Leclerc, N.; Khalil, A.; Kelley, J. B.

10.1101/2023.06.16.545321 — cell biology — Posted on 2023-06-17

2032 Warming affects routine swimming activity and novel odour molecular response in larval zebrafish

Sourisse, J. M.; Schunter, C.; Bonzi, L. C.; Semmelhack, J.

10.1101/2023.06.16.545285 — molecular biology — Posted on 2023-06-16

2033 Changing protein-DNA interactions promote ORC binding site exchange during replication origin licensing.

Zhang, A.; Friedman, L. J.; Gelles, J.; Bell, S. P.

10.1101/2023.06.16.545300 — molecular biology — Posted on 2023-06-16

2034 Cochaperones convey the energy of ATP hydrolysis for directional action of Hsp90

Vollmar, L.; Schimpf, J.; Hermann, B.; Hugel, T.

10.1101/2023.06.16.545234 — biophysics — Posted on 2023-06-16

2035 The principles of peptide selection by the transporter associated with antigen processing

Lee, J.; Oldham, M. L.; Manon, V.; Chen, J.

10.1101/2023.06.16.545308 — biophysics — Posted on 2023-06-17

2036 The Effects of Nitric Oxide on Choroidal Gene Expression

Merkley, M.; Soriano, D.; Jones, K. L.; Summers, J. A.

10.1101/2023.06.16.545343 — cell biology — Posted on 2023-06-16

2037 Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2

Cremer, T.; Hoelen, H.; van de Weijer, M. L.; Janssen, G.; Costa, A. I.; van Veelen, P.; Lebbink, R. J.; Wiertz, E.

10.1101/2023.06.16.545333 — cell biology — Posted on 2023-06-17

2038 HSP90 inhibitor NVP-HSP990 alleviates rotavirus infection

Zhu, Q.; Cao, Y.; Wu, X.; Xie, Z.; Guo, Y.; Meng, D.; Zhou, X.; Wu, Y.; Li, J.; He, h.

10.1101/2023.06.15.545197 — microbiology — Posted on 2023-06-16

2039 The pentameric complex is not required for vertical transmission of cytomegalovirus in seronegative pregnant rhesus macaques

Wang, H.-Y.; Taher, H.; Kreklywich, C. N.; Schmidt, K. A.; Scheef, E. A.; Barfield, R.; Otero, C. E.; Valencia, S.; Crooks, C. M.; Mirza, A.; Woods, K.; Burgt, N. V.; Kowalik, T. F.; Barry, P. A.; Hansen, S. G.; Tarantal, A. F.; Chan, C.; Streblow, D. N.; Picker, L. J.; Kaur, A.; Frueh, K.; Permar, S. R.; Malouli, D.

10.1101/2023.06.15.545169 — microbiology — Posted on 2023-06-16

2040 Structure and dynamics of differential ligand binding in the human {rho}-type GABA(A) receptor

Cowgill, J.; Fan, C.; Haloi, N.; Tobiasson, V.; Zhuang, Y.; Howard, R. J.; Lindahl, E.

10.1101/2023.06.16.545288 — biophysics — Posted on 2023-06-17

2041 Autoencoder Model for Translating Omics Signatures

Meimetis, N.; Pullen, K. M.; Zhu, D. Y.; Nilsson, A.; Hoang, T. N.; Magliacane, S.; Lauffenburger, D. A.

10.1101/2023.06.08.544243 — bioinformatics — Posted on 2023-06-16

2042 CC + : A Searchable Database of Validated Coiled coils in PDB Structures and AlphaFold2 Models

Kumar, P.; Petrenas, R.; Dawson, W. M.; Schweke, H.; Levy, E. D.; Woolfson, D.

10.1101/2023.06.16.541900 — bioinformatics — Posted on 2023-06-17

2043 A transcriptional cell atlas identifies the decline in the AT2 niche in aged human lungs

Liu, X.; Zhang, X.; Yao, C.; Liang, J.; Noble, P. W.; Jiang, D.

10.1101/2023.06.16.545378 — cell biology — Posted on 2023-06-17

2044 Screening for variable drug responses using human iPSC cohorts

Platani, M.; Jiang, H.; Davidson, L.; Lamond, A. I.; Swedlow, J. R.

10.1101/2023.06.16.545161 — cell biology — Posted on 2023-06-17

2045 Polymer biodegradation by Halanaerobium promotes reservoir souring during hydraulic fracturing.

Scheffer, G.; Chakraborty, A.; Amundson, K.; Khan, R.; Wilkins, M.; Wrighton, K.; Evans, P.; Hubert, C. R.

10.1101/2023.06.16.545336 — microbiology — Posted on 2023-06-16

2046 Low gH/gL (sub)species-specific antibody levels indicate elephants at risk of fatal elephant endotheliotropic herpesvirus hemorrhagic disease

Hoornweg, T. E.; Schaftenaar, W.; Rutten, V.; de Haan, C. A. M.

10.1101/2023.06.15.545196 — microbiology — Posted on 2023-06-16

2047 Topological constraints and finite-size effects in quantitative polymer models of chromatin organization

Abdulla, A. Z.; Tortora, M. M.; Vaillant, C.; Jost, D.

10.1101/2023.06.16.545312 — biophysics — Posted on 2023-06-16

2048 InCellCryst - A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins

Schoenherr, R.; Boger, J.; Lahey-Rudolph, J. M.; Harms, M.; Kaiser, J.; Nachtschatt, S.; Wobbe, M.; Duden, R.; Koenig, P.; Bourenkov, G. P.; Schneider, T. R.; Redecke, L.

10.1101/2023.06.16.545255 — biophysics — Posted on 2023-06-16

2049 Inferring the direction of introgression using genomic sequence data

Thawornwattana, Y.; Huang, J.; Flouri, T.; Mallet, J. L.; Yang, Z.

10.1101/2023.06.16.545313 — evolutionary biology — Posted on 2023-06-16

2050 TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway.

Nguyen, T. T.; Mitchell, J. M.; Kiel, M. D.; Jones, K. L.; Williams, T. J.; Nichols, J. T.; Van Otterloo, E.

10.1101/2023.06.16.545376 — developmental biology — Posted on 2023-06-16

2051 Auditory cortex anatomy reflects multilingual phonological experience

Kepinska, O.; Dalboni da Rocha, J.; Tuerk, C.; Hervais-Adelman, A.; Bouhali, F.; Green, D.; Price, C. J.; Golestani, N.

10.1101/2023.06.16.545298 — neuroscience — Posted on 2023-06-16

2052 Reports of the death of brain-behavior associations have been greatly exaggerated

Makowski, C.; Brown, T. T.; Zhao, W.; Hagler, D. J.; Parekh, P.; Garavan, H.; Nichols, T. E.; Jernigan, T. L.; Dale, A. M.

10.1101/2023.06.16.545340 — neuroscience — Posted on 2023-06-16

2053 The role of GpsB in cell morphogenesis of Staphylococcus aureus

Costa, S. F.; Saraiva, B. M.; Veiga, H.; Marques, L. B.; Schaper, S.; Sporniak, M.; Vega, D. E.; Jorge, A. M.; Duarte, A. M.; Brito, A. D.; Tavares, A. C.; Reed, P.; Pinho, M. G.

10.1101/2023.06.16.545294 — microbiology — Posted on 2023-06-16

2054 Genome-resolved meta-omics unveils rock-hosted lifestyle of enigmatic DPANN archaea

Takamiya, H.; Kouduka, M.; Kato, S.; Suga, H.; Oura, M.; Yokoyama, T.; Suzuki, M.; Mori, M.; Kanai, A.; Suzuki, Y.

10.1101/2023.06.16.545063 — microbiology — Posted on 2023-06-16

2055 DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2

Bjarnason, S.; McIvor, J. A. P.; Prestel, A.; Demeny, K. S.; Bullerjahn, J. T.; Kragelund, B. B.; Mercadante, D.; Heidarsson, P. O.

10.1101/2023.06.16.545083 — biophysics — Posted on 2023-06-16

2056 Landscape of semi-extractable RNAs across five human cell lines

Zeng, C.; Chujo, T.; Hirose, T.; Hamada, M.

10.1101/2022.10.03.510572 — bioinformatics — Posted on 2023-06-16

2057 Integrated multimodal cell atlas of Alzheimer's disease

Gabitto, M. I.; Travaglini, K. J.; Rachleff, V. M.; Kaplan, E. S.; Long, B.; Ariza, J.; Ding, Y.; Mahoney, J. T.; Dee, N.; Goldy, J.; Melief, E. J.; Barlow, S. T.; Brouner, K.; Campos, J.; Campos, J.; Carr, A. J.; Casper, T.; Chakrabarty, R.; Clark, M.; Cool, J.; Dalley, R.; Darvas, M.; Ding, S.-L.; Dolbeare, T.; Egdorf, T.; Esposito, L.; Ferrer, R.; Gala, R.; Gary, A.; Gelfand, E.; Gloe, J.; Guilford, N.; Guzman, J.; Hirschstein, D.; Ho, W.; Hupp, M.; Jarksy, T.; Johansen, N.; Kalmbach, B. E.; Keene, L. M.; Khawand, S.; Kilgore, M.; Kirkland, A.; Kunst, M.; Lee, B. R.; Leytze, M.; Mac Donald,

10.1101/2023.05.08.539485 — genomics — Posted on 2023-06-16

2058 Rapid Adaption of Cellular Metabolic Rate to the microRNA Complements of Mammals

Fromm, B.; Sorger, T.

10.1101/2022.11.24.517858 — evolutionary biology — Posted on 2023-06-16

2059 Fusobacterium sphaericum sp. nov., isolated from a human colon tumor, is prevalent in various human body sites and induces IL-8 secretion from colorectal cancer cells

Zepeda-Rivera, M. A.; Eisele, Y.; Baryiames, A.; Wu, H.; LaCourse, K. D.; Jones, D. S.; Hauner, H.; Dewhirst, F. E.; Minot, S. S.; Johnston, C. D.; Bullman, S.

10.1101/2023.06.16.545380 — microbiology — Posted on 2023-06-16

2060 Differentially abundant bacteria drive the N2-fixation of a widespread moss in the forest-tundra transition zone

Escolastico-Ortiz, D. A.; Blasi, C.; Bellenger, J.-P.; Derome, N.; Villarreal-A, J. C.

10.1101/2023.06.16.545342 — microbiology — Posted on 2023-06-16

2061 Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model

Plumlee, C. R.; Barrett, H. W.; Shao, D. E.; Lien, K. A.; Cross, L. M.; Cohen, S. B.; Edlefsen, P. T.; Urdahl, K. B.

10.1101/2023.03.22.533820 — microbiology — Posted on 2023-06-16

2062 Early cellular mechanism of type I interferon-driven susceptibility to tuberculosis

Kotov, D. I.; Lee, O. V.; Fattinger, S. A.; Langner, C.; Guillen, J. V.; Peters, J. M.; Moon, A.; Burd, E. M.; Witt, K. C.; Stetson, D. B.; Jaye, D. L.; Bryson, B. D.; Vance, R. E.

10.1101/2022.10.06.511233 — immunology — Posted on 2023-06-16

2063 LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation

Fahmy, A. M.; Cannon, T.; Paredes, C. H.; Ahmadi, A.; Xu, Y. Z.; Barette, B.; Ibrahim, M.; Lanoix, J.; Arango-Duque, G.; Schurr, E.; Chevet, E.; Thibault, P.; Gruenheid, S.; McBride, H.; Desjardins, M.

10.1101/2023.06.14.545012 — immunology — Posted on 2023-06-16

2064 Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders

Hiramoto, T.; Sumiyoshi, A.; Kato, R.; Yamauchi, T.; Kang, G.; Matsumura, B.; Stevens, L. J.; Ryoke, R.; Nonaka, H.; Machida, A.; Nomoto, K.; Mogi, K.; Kikusui, T.; Kawashima, R.; Hiroi, N.

10.1101/2023.06.14.545013 — neuroscience — Posted on 2023-06-16

2065 Modelling Spontaneous Firing Activity of the Motor Cortex in a Spiking Neural Network with Random and Local Connectivity

Haggie, L.; Besier, T. F.; McMorland, A. J.

10.1101/2022.12.12.520017 — neuroscience — Posted on 2023-06-16

2066 Protracted development of visuo-proprioceptive integration for uni-and bimanual motor coordination

Martel, M.; Ossandon, J. P.; Habets, B.; Heed, T.

10.1101/601435 — neuroscience — Posted on 2023-06-16

2067 The nuclear import receptor Kapβ2 protein modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD

cicardi, M. e.; Kankate, V.; Sriramoji, S.; Krishnamurthy, K.; ShamamandriMarkandaiah, S.; Verdone-Morris, B.; Girdhar, A.; Nelson, A. T.; Rivas, L. B.; Boehringer, A.; Haeusler, A.; Pasinelli, P.; Guo, L.; Trotti, D.

10.1101/2022.09.30.510384 — neuroscience — Posted on 2023-06-16

2068 Spatial constraints subvert microbial arms race

Copeland, R.; Zhang, C.; Hammer, B. K.; Yunker, P. J.

10.1101/2023.06.16.545151 — biophysics — Posted on 2023-06-16

2069 A unified analysis of atlas single cell data

Chen, H.; Nguyen, N. D.; Ruffalo, M.; Bar-Joseph, Z.

10.1101/2022.08.06.503038 — bioinformatics — Posted on 2023-06-16

2070 Deciphering Phage-Host Specificity Based on the Association of Phage Depolymerases and Bacterial Surface Glycan with Deep Learning

Yang, Y.; Dufault-Thompson, K.; Yan, W.; Cai, T.; Xie, L.; Jiang, X.

10.1101/2023.06.16.545366 — bioinformatics — Posted on 2023-06-16

2071 Cell segmentation for high-resolution spatial transcriptomics

Chen, H.; Li, D.; Bar-Joseph, Z.

10.1101/2023.01.11.523658 — bioinformatics — Posted on 2023-06-16

2072 Peanut Shell Carbon Nanocellulose Preparation, Analysis and Plausible Role in Regenerative Medicine Using Mesenchymal Stem Cell Line C3H10t1/2

Priya, K.; Bhatia, Y.; Rai, S.; Mahajan, N.

10.1101/2023.04.19.537474 — bioengineering — Posted on 2023-06-16

2073 Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle.

Dodge, G. J.; Anderson, A. J.; He, Y.; Viner, R.; Imperiali, B.

10.1101/2023.06.16.545297 — biochemistry — Posted on 2023-06-16

2074 Borrelia PeptideAtlas: A proteome resource of common Borrelia burgdorferi isolates for Lyme research

Reddy, P. J.; Sun, Z.; Wippel, H. H.; Baxter, D. H.; Swearingen, K. E.; Shteynberg, D. D.; Midha, M. K.; Caimano, M. J.; Strle, K.; Choi, Y.; Chan, A. P.; Schork, N. J.; Moritz, R. L.

10.1101/2023.06.16.545244 — biochemistry — Posted on 2023-06-16

2075 Fluorogenic Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide Activated SIRT7

Bolding, J. E.; Nielsen, A. L.; Jensen, I.; Ryberg, L. A.; Jameson, S. T.; Harris, P.; Peters, G. H.; Denu, J.; Rogers, J. M.; Olsen, C. A.

10.1101/2023.06.16.545261 — biochemistry — Posted on 2023-06-16

2076 Antibodies against Elapidae and Viperidae snake venoms: in vivo neutralization and mechanistic insights

Kumar, A.; Madni, Z. K.; Chaturvedi, S.; Salunke, D. M.

10.1101/2023.06.16.545250 — biochemistry — Posted on 2023-06-16

2077 Ants integrate proprioception, visual context and efference copies to make robust predictions.

Dauzere-Peres, O.; Wystrach, A.

10.1101/2023.03.29.534571 — animal behavior and cognition — Posted on 2023-06-16

2078 CRISPR/Cas9-based depletion of 16S ribosomal RNA improves library complexity of single-cell RNA-sequencing

Wang, K.-T.; Adler, C. E.

10.1101/2023.05.25.542286 — genomics — Posted on 2023-06-16

2079 Adolescent length growth spurts in bonobos and other primates: Mind the scale

Berghaenel, A.; Stevens, J. M. G.; Hohmann, G.; Deschner, T.; Behringer, V.

10.1101/2023.01.26.525764 — evolutionary biology — Posted on 2023-06-16

2080 Evolution of ion channels in cetaceans a natural experiment in the tree of life

Uribe, C.; Nery, M.; Zavala, K.; Mardones, G.; Riadi, G.; Opazo, J.

10.1101/2023.06.15.545160 — evolutionary biology — Posted on 2023-06-16

2081 Differential effects of soil conservation practices on arthropods and crop yields

Lichtenberg, E. M.; Milosavljevic, I.; Campbell, A. J.; Crowder, D.

10.1101/2021.12.06.471474 — ecology — Posted on 2023-06-16

2082 LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia Through MiT-TFE Transcription Factor Inhibition

Yadavalli, N.; Ferguson, S. M.

10.1101/2022.12.17.520834 — cell biology — Posted on 2023-06-16

2083 Cellular Allostatic Load is linked to Increased Energy Expenditure and Accelerated Biological Aging

Bobba-Alves, N.; Sturm, G.; Lin, J.; Ware, S. A.; Karan, K. R.; Monzel, A. S.; Bris, C.; Procaccio, V.; Lenaers, G.; Higgins-Chen, A.; Levine, M.; Horvath, S.; Santhanam, B. S.; Kaufman, B. A.; Hirano, M.; Epel, E. S.; Picard, M.

10.1101/2022.02.22.481548 — cell biology — Posted on 2023-06-16

2084 ReLo is a simple and quick colocalization assay to identify and characterize direct protein-protein interactions

Salgania, H. K.; Metz, J.; Jeske, M.

10.1101/2022.03.04.482790 — cell biology — Posted on 2023-06-16

2085 Comparative genomics of Japanese encephalitis virus shows low rates of recombination and a suite of sites under episodic diversifying selection

Sistrom, M.; Andrews, H.; Edwards, D.

10.1101/2023.06.15.545193 — microbiology — Posted on 2023-06-16

2086 The roles of GpsB and DivIVA in Staphylococcus aureus growth and division

Sutton, J. A. F.; Cooke, M.; Tinajero-Trejo, M.; Wacnik, K.; Salamaga, B.; Portman-Ross, C.; Lund, V. A.; Hobbs, J. K.; Foster, S. J.

10.1101/2023.06.16.545239 — microbiology — Posted on 2023-06-16

2087 Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

Castano, A.; Silvestre, M.; Wells, C. I.; Sanderson, J. L.; Ferrer, C. A.; Ong, H. W.; Lang, Y.; Richardson, W.; Silvaroli, J. A.; Bashore, F. M.; Smith, J. L.; Genereux, I. M.; Dempster, K.; Drewry, D. H.; Pabla, N. S.; Bullock, A. N.; Benke, T. A.; Ultanir, S.; Axtman, A. D.

10.1101/2023.04.24.538049 — neuroscience — Posted on 2023-06-16

2088 A scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds

Lin, K.; Chang, Y.-C.; Billmann, M.; Ward, H. N.; Le, K.; Hassan, A. Z.; Bhojoo, U.; Chan, K.; Costanzo, M.; Moffat, J.; Boone, C.; Bielinsky, A.-K.; Myers, C. L.

10.1101/2023.06.16.545157 — systems biology — Posted on 2023-06-16

2089 Optimizing 5'UTRs for mRNA-delivered gene editing using deep learning

Castillo Hair, S.; Fedak, S.; Wang, B.; Linder, J.; Havens, K.; Certo, M.; Seelig, G.

10.1101/2023.06.15.545194 — synthetic biology — Posted on 2023-06-16

2090 Heat stress impairs centromere structure and segregation of meiotic chromosomes in Arabidopsis

Crhak Khaitova, L.; Mikulkova, P.; Pecinkova, J.; Kalidass, M.; Heckmann, S.; Lermontova, I.; Riha, K.

10.1101/2023.04.19.537519 — plant biology — Posted on 2023-06-16

2091 Repurposing Remdesivir for COVID-19: Computational Drug Design Targeting SARS-CoV-2 RNA Polymerase and Main Protease using Molecular Dynamics Approach

Shikder, M.; Ahmed, K. A.; Moin, A. T.; Patil, R. B.; Hasib, T. A.; Hossan, M. I.; Mahasin, D.; Sakib, M. N.; Ahmed, I.; Patel, H.; Chowdhury, A. S.

10.1101/2023.06.15.545129 — bioinformatics — Posted on 2023-06-16

2092 FixNCut: Single-cell genomics through reversible tissue fixation and dissociation

10.1101/2023.06.16.545221 — bioinformatics — Posted on 2023-06-16

2093 Efficient Sex Separation by Exploiting Differential Alternative Splicing of a Dominant Marker in Aedes aegypti

Weng, S.-C.; Antoshechkin, I.; Marois, E.; Akbari, O. S.

10.1101/2023.06.16.545348 — bioengineering — Posted on 2023-06-16

2094 High-confidence placement of difficult-to-fit fragments into electron density by using anomalous signals - a case study using hits targeting SARS-CoV-2 non-structural protein 1

Kozielski, F. G.; Ma, S.; Bowler, M. W.; Mykhaylyk, V.; Pinotsis, N.

10.1101/2023.06.16.545251 — biochemistry — Posted on 2023-06-16

2095 SARS-CoV-2 Delta Variant Remains Viable in Environmental Biofilms found in Meat Packaging Plants

Chitlapilly Dass, S.; Featherstone, A. B.; Mathijssen, A. J.; Brown, A. C.

10.1101/2023.06.15.545172 — ecology — Posted on 2023-06-16

2096 Cdc48 and its co-factor Ufd1 segregate CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe.

Nakase, Y.; Murakami, H.; Suma, M.; Nagano, K.; Wakuda, A.; Kitagawa, T.; Matsumoto, T.

10.1101/2023.06.15.545183 — molecular biology — Posted on 2023-06-16

2097 Bacterial tolerance to host-exuded specialized metabolites structures the maize root microbiome

Thoenen, L.; Giroud, C.; Kreuzer, M.; Waelchli, J.; Gfeller, V.; Deslandes-Herold, G.; Mateo, P.; Robert, C. A. M.; Ahrens, C.; Rubio-Somoza, I.; Erb, M.; Schlaeppi, K.

10.1101/2023.06.16.545238 — microbiology — Posted on 2023-06-16

2098 Supraclavicular brown adipocytes originate from Tbx1+ myoprogenitors

Huang, Z.; Gu, C.; Zhang, Z.; Arianti, R.; Swaminathan, A.; Tran, K.; Battist, A.; Kristof, E.; Ruan, H.-B.

10.1101/2023.06.16.545229 — developmental biology — Posted on 2023-06-16

2099 Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors

Cooper, F.; Souilhol, C.; Haston, S.; Gray, S.; Boswell, K.; Gogolou, A.; Frith, T.; Stavish, D.; James, B. M.; Bose, D. A.; Dale, J. K.; Tsakiridis, A.

10.1101/2023.06.16.545269 — developmental biology — Posted on 2023-06-16

2100 All exons are not created equal - Exon vulnerability determines the effect of exonic mutations on splicing.

Holm, L. L.; Doktor, T. K.; Flugt, K. K.; Petersen, U. S. S.; Petersen, R.; Andresen, B. S.

10.1101/2023.06.14.544306 — molecular biology — Posted on 2023-06-14

2101 Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection

Garcia-Moreno, M.; Truman, R.; Chen, H.; Iselin, L.; Lenz, C. E.; Lee, J.; Dicker, K.; Noerenberg, M.; Sohier, T. J. M.; Palmalux, N.; Jaervelin, A. I.; Kamel, W.; Ruscica, V.; Ricci, E. P.; Davis, I.; Mohammed, S.; Castello, A.

10.1101/2023.06.14.544764 — molecular biology — Posted on 2023-06-14

2102 Programmable RNA-guided endonucleases are widespread in eukaryotes and their viruses

Jiang, K.; Lim, J.; Sgrizzi, S.; Trinh, M.; Kayabolen, A.; Yutin, N.; Koonin, E. V.; Abudayyeh, O. O.; Gootenberg, J. S.

10.1101/2023.06.13.544871 — molecular biology — Posted on 2023-06-14

2103 Longitudinal characterization of the captive adult and tadpole Wyoming toad (Anaxyrus baxteri) microbiome

Scarberry, N.; McAdams, Z. L.; Benson, D.; Herrick, J.; Moore, B.; Ericsson, A. C.

10.1101/2023.06.13.544657 — microbiology — Posted on 2023-06-16

2104 Lost in the WASH. The functional human WASH complex 1 gene is on chromosome 20

Cerdan, D.; Tress, M. L.

10.1101/2023.06.14.544951 — molecular biology — Posted on 2023-06-14

2105 Self-reversal facilitates the resolution of HMCES-DNA protein crosslinks in cells

Rua-Fernandez, J.; Lovejoy, C. A.; Mehta, K. P. M.; Paulin, K. A.; Toudji, Y. T.; Eichman, B. F.; Cortez, D.

10.1101/2023.06.14.544844 — molecular biology — Posted on 2023-06-14

2106 RAVER1 interconnects lethal EMT and miR/RISC activity by the control of alternative splicing

Wedler, A.; Bley, N.; Glass, M.; Mueller, S.; Schian, L.; Obika, K. B.; Lederer, M.; Misiak, C.; Fuchs, T.; Koehn, M.; Jacob, R.; Gutschner, T.; Ihling, C.; Sinz, A.; Huettelmaier, S.

10.1101/2023.06.14.544976 — molecular biology — Posted on 2023-06-14

2107 Spontaneous activity in peripheral sensory nerves - A systematic review

Choi, D.; Goodwin, G.; Stevens, E. B.; Soliman, N.; Namer, B.; Denk, F.

10.1101/2023.06.13.544736 — neuroscience — Posted on 2023-06-16

2108 Quantifying innervation facilitated by deep learning in wound healing

Mehta, A. S.; Teymoori, S.; Recendez, C.; Fregoso, D.; Gallegos, A.; Yang, H.-Y.; Isseroff, R. R.; Zhao, M.; Gomez, M.

10.1101/2023.06.14.544960 — molecular biology — Posted on 2023-06-14

2109 Genomic epidemiology of third-generation cephalosporin-resistant Escherichia coli from Argentinian pig and dairy farms reveals animal-specific patterns of co-resistance and resistance mechanisms

Mounsey, O.; Marchetti, L.; Parada, J.; Alarcon, L. V.; Aliverti, F.; Avison, M. B.; Ayala, C. S.; Ballesteros, C.; Best, C. M.; Bettridge, J.; Buchamer, A.; Buldain, D.; Carranza, A.; Isgro, M. C.; Demeritt, D.; Escobar, M. P.; Castillo, L. G.; Jaureguiberry, M.; Lucas, M. F.; Madoz, L. V.; Marconi, M. J.; Moiso, N.; Nievas, H. D.; Montes de Oca, M. A. R.; Reding, C.; Reyher, K. K.; Vass, L.; Williams, S.; Giraudo, J.; De La Sota, R. L.; Mestorino, N.; Moredo, F. A.; Pellegrino, M.

10.1101/2023.06.15.545115 — microbiology — Posted on 2023-06-16

2110 Yersinia Type III-Secreted Effectors Evade the Caspase-4 Inflammasome in Human Cells

Zhang, J.; Brodsky, I. E.; Shin, S.

10.1101/2023.01.24.525473 — microbiology — Posted on 2023-06-16

2111 Mapping SARS-CoV-2 antigenic relationships and serological responses

Wilks, S. H.; Muhlemann, B.; Shen, X.; Tureli, S.; LeGresley, E. B.; Netzl, A.; Caniza, M. A.; Chacaltana-Huarcaya, J. N.; Corman, V. M.; Daniell, X.; Datto, M. B.; Dawood, F. S.; Denny, T. N.; Drosten, C.; Fouchier, R. A. M.; Garcia, P. J.; Halfmann, P. J.; Jassem, A.; Jeworowski, L. M.; Jones, T. C.; Kawaoka, Y.; Krammer, F.; McDanal, C.; Pajon, R.; Simon, V.; Stockwell, M.; Tang, H.; van Bakel, H.; Veguilla, V.; Webby, R.; Montefiori, D. C.; Smith, D. J.

10.1101/2022.01.28.477987 — immunology — Posted on 2023-06-16

2112 M3NetFlow: a novel multi-scale multi-hop modular graph AI model for multi-omics data integration and signaling network inference

Zhang, H.; Goedegebuure, P.; Ding, L.; Hawkins, W.; DeNardo, D.; Fields, R.; Chen, Y.; Li, F.

10.1101/2023.06.15.545130 — bioinformatics — Posted on 2023-06-16

2113 Acceleration of Large-Scale Single Cell Differential Gene Expression Analysis with FastDE

Connolly, E.; Aluru, M.; Chocklingam, S.; Dhere, V.; Gibson, G.; Pan, T.

10.1101/2023.06.15.545003 — bioinformatics — Posted on 2023-06-16

2114 A biologically inspired repair mechanism for neuronal reconstructions with a focus on human dendrites

Groden, M.; Moessinger, H. M.; Schaffran, B.; DeFelipe, J. D.; Benavides-Piccione, R.; Cuntz, H.; Jedlicka, P.

10.1101/2023.06.15.545190 — neuroscience — Posted on 2023-06-16

2115 Task-driven neural network models predict neural dynamics of proprioception

Vargas, A. M.; Bisi, A.; Chiappa, A. S.; Versteeg, C.; Miller, L. E.; Mathis, A.

10.1101/2023.06.15.545147 — neuroscience — Posted on 2023-06-16

2116 Temporal Dynamics of Brain Activity Predicting Illusory Agency over Involuntary Movements

Veillette, J. P.; Lopes, P.; Nusbaum, H. C.

10.1101/2023.05.06.539706 — neuroscience — Posted on 2023-06-16

2117 Using mixture density networks to emulate a stochastic within-host model of Francisella tularensis infection

Carruthers, J.; Finnie, T.

10.1101/2023.06.15.545189 — systems biology — Posted on 2023-06-16

2118 dadi-cli: Automated and distributed population genetic model inference from allele frequency spectra

Huang, X.; Struck, T. J.; Davey, S. W.; Gutenkunst, R. N.

10.1101/2023.06.15.545182 — bioinformatics — Posted on 2023-06-16

2119 The FIGNL1-FIRRM complex is required to complete meiotic recombination in the mouse and prevents massive DNA damage-independent RAD51 and DMC1 loading

Zainu, A.; Dupaigne, P.; Bouchouika, S.; Cau, J.; Clement, J. A. J.; Auffret, P.; Ropars, V.; Charbonnier, J.-B.; de Massy, B.; Kumar, R.; Baudat, F.

10.1101/2023.05.17.541096 — genetics — Posted on 2023-06-16

2120 Dengue virus preferentially uses human and mosquito non-optimal codons

Castellano, L. A.; McNamara, R. J.; Pallares, H. M.; Gamarnik, A. V.; Alvarez, D. E.; Bazzini, A. A.

10.1101/2023.06.14.544804 — molecular biology — Posted on 2023-06-14

2121 SULFATED POLYSACCHARIDE FROM BROWN ALGAE DICTYOTA CARIBAEA STIMULATES MACROPHAGES TO AN ANTITUMORAL PHENOTYPE

Assef, A. N. B.; Teles, F. B.; Cinelli, L. P.; Wilke, D. V.

10.1101/2023.06.15.545132 — immunology — Posted on 2023-06-16

2122 No evidence for an effect of chronic boat noise on the fitness of reared water fleas

Prosnier, L.; Rojas, E.; Medoc, V.

10.1101/2022.11.20.517267 — ecology — Posted on 2023-06-16

2123 Comparative analysis of PDZ-binding motifs in the diacylglycerol kinase family

Zambo, B.; Gogl, G.; Morlet, B.; Eberling, P.; Negroni, L.; Moine, H.; Trave, G.

10.1101/2023.06.15.545061 — molecular biology — Posted on 2023-06-15

2124 Molecular basis of Progressive Familial Intrahepatic Cholestasis 3. A proteomics study.

Guerrero, L.; Carmona-Rodriguez, L.; Millhano Santos, F.; Ciordia, S.; Stark, L.; Hierro, L.; Vicent, D.; Corrales, F. J.

10.1101/2023.06.15.545058 — molecular biology — Posted on 2023-06-15

2125 Vitamin B12 status and folic acid supplementation influence mitochondrial heteroplasmy levels in mice as they age.

Walsh, D. J.; Bernard, D. J.; Fiddler, J. L.; Pangilinan, F.; Esposito, M.; Harold, D.; Field, M. S.; Parle-McDermott, A.; Brody, L. C.

10.1101/2023.06.15.545050 — molecular biology — Posted on 2023-06-15

2126 ERAP1 Shows Distinct Regulatory Mechanisms on Blood Pressure Modulation Between Males and Females

Ding, M.; Heydarpour, M.; Gomez, D. H.; Aljaibeji, H.; Parksook, W. W.; Peng, L.; Pojoga, L. H.; Romero, J. R.; Williams, G. H.

10.1101/2023.06.07.544152 — molecular biology — Posted on 2023-06-15

2127 Polar accumulation of pyoverdin facilitates rapid exit from stationary phase

Moreno-Fenoll, C.; Ardre, M.; Rainey, P. B.

10.1101/2021.07.27.453990 — microbiology — Posted on 2023-06-16

2128 Translational regulation enhances distinction of cell types in the nervous system

Ichinose, T.; Kondo, S.; Kanno, M.; Shichino, Y.; Mito, M.; Iwasaki, S.; Tanimoto, H.

10.1101/2023.06.15.545207 — neuroscience — Posted on 2023-06-16

2129 Validation of a Radio frequency identification system for tracking location of laying hens in a quasi-commercial aviary system

Gebhardt-Henrich, S. G.; Kashev, A.; Petelle, M. B.; Toscano, M. J.

10.1101/2023.02.16.528820 — animal behavior and cognition — Posted on 2023-06-16

2130 Nature and nurture: comparing mouse behavior in classic versus revised anxiety-like and social behavioral assays in genetically or environmentally defined groups

Ronquillo, J.; Nguyen, M. T.; Rothi, L.; Bui-Tu, T.-D.; Yang, J.; Halladay, L. R.

10.1101/2023.06.16.545212 — animal behavior and cognition — Posted on 2023-06-16

2131 Chemodiversity affects preference for Tanacetum vulgare chemotypes in two aphid species

Neuhaus-Harr, A.; Ojeda-Prieto, L.; Eilers, E.; Muller, C.; Weisser, W. W.; Heinen, R.

10.1101/2023.03.16.532937 — ecology — Posted on 2023-06-16

2132 Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy

Hedaya, O. M.; Subbaiah, K. C.; Jiang, F.; Xie, L. H.; Wu, J.; Khor, E.; Zhu, M.; Mathews, D.; Proschel, C.; Yao, P.

10.1101/2023.06.15.545153 — molecular biology — Posted on 2023-06-15

2133 Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease

Gridina, M.; Popov, A.; Shadskiy, A.; Torgunakov, N.; Kechin, A.; Khrapov, E.; Ryzhkova, O.; Filipenko, M.; Fishman, V.

10.1101/2023.06.15.545138 — molecular biology — Posted on 2023-06-15

2134 Impact of brain parcellation on prediction error in models of cognition and demographics

Litwinczuk, M. C.; Muhlert, N.; Trujillo-Barreto, N.; Woollams, A.

10.1101/2023.02.10.528041 — neuroscience — Posted on 2023-06-16

2135 Network depth affects inference of gene sets from bacterial transcriptomes using denoising autoencoders

Kion-Crosby, W. B.; Barquist, L.

10.1101/2023.05.30.542622 — bioinformatics — Posted on 2023-06-16

2136 Improved RNA stability estimation through Bayesian modeling reveals most bacterial transcripts have sub-minute half-lives

Jenniches, L.; Michaux, C.; Reichardt, S.; Vogel, J.; Westermann, A. J.; Barquist, L.

10.1101/2023.06.15.545072 — microbiology — Posted on 2023-06-15

2137 Unraveling Genomic Diversity in Pseudomonas aeruginosa Cystic Fibrosis Lung Infection and Its Impact on Antimicrobial Resistance

Vanderwoude, J.; Azimi, S.; Read, T.; Diggle, S. P.

10.1101/2023.06.14.544983 — microbiology — Posted on 2023-06-15

2138 The structure of the OmpA/Pal protein of Anaplasma phagocytophilum

Cadby, I. T.

10.1101/2023.06.15.545016 — microbiology — Posted on 2023-06-16

2139 Molecular tuning of sea anemone stinging

He, L. S.; Qi, Y.; Allard, C. A.; Valencia-Montoya, W. A.; Krueger, S. P.; Weir, K.; Seminara, A.; Bellono, N. W.

10.1101/2023.06.15.545144 — physiology — Posted on 2023-06-16

2140 A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

Liang, S.; Tran, E.; Du, X.; Dong, J.; Sudholz, H.; Chen, H.; Qu, Z.; Huntington, N.; Babon, J.; Kershaw, N.; Zhang, Z.-Y.; Baell, J.; Wiede, F.; Tiganis, T.

10.1101/2023.06.16.545220 — cancer biology — Posted on 2023-06-16

2141 Building alternative splicing and evolution-aware sequence-structure maps for protein repeats

Szatkownik, A.; Zea, D. J.; Richard, H.; Laine, E.

10.1101/2023.04.29.538821 — bioinformatics — Posted on 2023-06-16

2142 Plasticity of the proteasome-targeting signal Fat10 enhances substrate degradation

Negi, H.; Ravichandran, A.; DasGupta, P.; Reddy, S.; Das, R.

10.1101/2022.07.15.499953 — biochemistry — Posted on 2023-06-16

2143 Impact of Streptococcus pneumoniae biosynthesis gene mutations on epithelial microinvasion and cellular responses

Weight, C. M.; Pollara, G. M.; Betts, M.; Ragazzini, R.; Connor, M.; Ramos-Sevillano, E.; Reine, J.; Whelan, M.; Guerra-Assuncao, J. A.; Bonfanti, P.; Jolly, C.; Noursadeghi, M. C.; Ferreira, D.; Brown, J.; Heyderman, R. S.

10.1101/2023.06.15.545009 — microbiology — Posted on 2023-06-15

2144 Physical interactions trigger Streptomyces to prey on yeast using natural products and lytic enzymes

Yamada, K.; Koroleva, A.; Tirkkonen, H.; Siitonen, V.; Laughlin, M.; Akhgari, A.; Mazurier, G.; Niemi, J.; Metsa-Ketela, M.

10.1101/2023.06.15.545052 — microbiology — Posted on 2023-06-15

2145 Ultraconserved bacteriophage genome sequence identified in 1300-year-old human palaeofaeces

Rozwalak, P.; Barylski, J.; Wijesekara, Y. R.; Dutilh, B. E.; Zielezinski, A.

10.1101/2023.06.01.543182 — microbiology — Posted on 2023-06-16

2146 The Importance of Individual Beliefs in Assessing Treatment Efficacy: Insights from Neurostimulation Studies

Fassi, L.; Hochman, S.; Daskalakis, Z. J.; Blumberger, D. M.; Cohen Kadosh, R.

10.1101/2020.12.06.411850 — neuroscience — Posted on 2023-06-16

2147 Impact of inoculation practices on microbiota assembly and community stability in a fabricated ecosystem

Lin, H.-H.; Torres, M.; Adams, C. A.; Andeer, P. F.; Owens, T. K.; Zhalnina, K.; Jabusch, L. K.; Carlson, H. K.; Kuehl, J. V.; Deutschbauer, A. M.; Northen, T. R.; Glass, N. L.; Mortimer, J. C.

10.1101/2023.06.13.544848 — plant biology — Posted on 2023-06-16

2148 Comprehensive regulatory networks for tomato organ development based on the genome and RNAome of microTom tomato

Xue, J.-Y.; Fan, H.-Y.; Zhen, Z.; Zhou, Y.-H.; Hu, S.-Y.; Li, S.-X.; Cheng, Y.-J.; Meng, X.-R.; Chen, F.; Shao, Z.-Q.; Van de Peer, Y.

10.1101/2022.12.01.518646 — plant biology — Posted on 2023-06-16

2149 Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells

Magnani, C. F.; Myburgh, R.; Brunn, S.; Chambovey, M.; Ponzo, M.; Volta, L.; Pellegrino, C.; Pascolo, S.; Miskey, C.; Ivics, Z.; Shizuru, J. A.; Neri, D.; Manz, M. G.

10.1101/2023.06.15.544946 — cancer biology — Posted on 2023-06-16

2150 Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

Ai, Z.; Niu, B.; Yin, Y.; Xiang, L.; Shi, G.; Duan, K.; Wang, S.; Hu, Y.; Zhang, C.; Zhang, C.; Rong, L.; Kong, R.; Chen, T.; Guo, Y.; Liu, W.; Li, N.; Zhao, S.; Zhu, X.; Mai, X.; Li, Y.; Wu, Z.; Zheng, Y.; Fu, J.; Ji, W.; Li, T.

10.1101/2023.06.15.545180 — developmental biology — Posted on 2023-06-16

2151 The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation

Cheng, Y.; Chan, F.; Kassis, J. A.

10.1101/2023.06.15.545191 — developmental biology — Posted on 2023-06-16

2152 CRISPR/Cas9-mediated Generation of COL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa

Alipour, F.; Ahmadraji, M.; Yektadoust, E.; Mohammadi, P.; Baharvand, H.; Basiri, M.

10.1101/2023.06.15.545036 — cell biology — Posted on 2023-06-16

2153 Hybrid Modeling of Engineered Biological Systems through Coupling Data-Driven Calibration of Kinetic Parameters with Mechanistic Prediction of System Performance

Cheng, Z.; Ronen, A.; Yuan, H.

10.1101/2023.06.14.545039 — microbiology — Posted on 2023-06-15

2154 Evolution of Shewanella oneidensis MR-1 in competition with Citrobacter freundii

Zhao, B.; Chen, G.; Chen, W.; Xiao, Y.

10.1101/2023.06.15.545074 — microbiology — Posted on 2023-06-15

2155 Ultraconserved bacteriophage genome sequence identified in 1300-year-old human paleofaeces

Rozwalak, P.; Barylski, J.; Wijesekara, Y. R.; Dutilh, B. E.; Zielezinski, A.

10.1101/2023.06.01.543182 — microbiology — Posted on 2023-06-16

2156 Intracortical remodelling increases in highly-loaded bone after exercise cessation

da Silva, R. G. C.; Sun, T. C.; Mishra, A. P.; Boyde, A.; Doube, M.; Riggs, C. M.

10.1101/2022.05.06.490923 — physiology — Posted on 2023-06-16

2157 WBSCR16 Determines Metabolic Flexibility Via Regulating Mitochondrial 16S rRNA Maturation

Huang, G.; Zhang, S.; Dong, Z.; Feng, Y.; Guo, W.; Zhang, C.; Shi, Y.; Zhao, Z.; Wang, J.; Ning, G.

10.1101/2023.06.15.545185 — cell biology — Posted on 2023-06-15

2158 Palmitoylation of the Hemagglutinin of Influenza B virus by ER-localized DHHC enzymes 1, 2, 4 and 6 is essential for virus replication

Meng, X.; Veit, M.

10.1101/2023.06.15.545201 — cell biology — Posted on 2023-06-16

2159 Genetic and transcriptomic analysis of hyphal constriction based on a novel assay method in the rice blast fungus

Cho, E.; Lee, S. H.; Jeong, M.; Mandal, S.; Park, S.-Y.; Nam, S. W.; Byeun, D. G.; Choi, J. K.; Lee, Y.-H.; Shin, J.-H.; Jeon, J.

10.1101/2023.06.14.545034 — microbiology — Posted on 2023-06-15

2160 The structure of the OmpA/Pal protein of Anaplasma phagocytophilum

Cadby, I. T.

10.1101/2023.06.15.545016 — microbiology — Posted on 2023-06-15

2161 Pump it up: bioelectric stimulation controls tissue shape and size

Shim, G.; Breinyn, I. B.; Martinez-Calvo, A.; Cohen, D. J.

10.1101/2022.11.22.517561 — bioengineering — Posted on 2023-06-15

2162 Structure of a heteropolymeric type 4 pilus from a monoderm bacterium

Anger, R.; Pieulle, L.; Shahin, M.; Valette, O.; Le Guenno, H.; Kosta, A.; Pelicic, V.; Fronzes, R.

10.1101/2023.06.15.545089 — microbiology — Posted on 2023-06-15

2163 Identification of potential molecular mimicry in pathogen-host interactions

Rich, K. D.; Srivastava, S.; Muthye, V.; Wasmuth, J. D.

10.1101/2023.06.14.544818 — microbiology — Posted on 2023-06-15

2164 The structure of the OmpA/Pal protein of Anaplasma phagocytophilum

Cadby, I. T.

10.1101/2023.06.15.545016 — microbiology — Posted on 2023-06-15

2165 Reconstructing visual illusory experiences from human brain activity

Cheng, F.; Horikawa, T.; Majima, K.; Tanaka, M.; Abdelhack, M.; Aoki, S. C.; Hirano, J.; Kamitani, Y.

10.1101/2023.06.15.545037 — neuroscience — Posted on 2023-06-15

2166 Characterization of cotton virus A, a novel and distinct member of the genus Caulimovirus with endogenous viral elements in Gossypium spp.

West-Ortiz, M.; Stuehler, D.; Pollock, E.; Wilson, J.; Preising, S.; Larrea-Sarmiento, A.; Alabi, O.; Fuchs, M.; Heck, M.; Olmedo-Velarde, A.

10.1101/2023.06.14.544975 — plant biology — Posted on 2023-06-15

2167 Concentration matters: mechanistic differences of stomatal CO2-responses at sub-ambient and above-ambient CO2 levels in Arabidopsis

Koolmeister, K.; Merilo, E.; Horak, H.; Kollist, H.

10.1101/2021.05.13.443984 — plant biology — Posted on 2023-06-15

2168 Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human NaV1.7 Channel

Ngo, K.; Mateos, D. L.; Han, Y.; Rouen, K. C.; Ahn, S.-H.; Wulff, H.; Clancy, C. E.; Yarov-Yarovoy, V.; Vorobyov, I.

10.1101/2023.02.27.530360 — biophysics — Posted on 2023-06-15

2169 Thresholding Gini Variable Importance with a single trained Random Forest: An Empirical Bayes Approach

Dunne, R. A.; Reguant, R.; Ramarao-Milne, P.; Szul, P.; Sng, L.; Lundberg, M.; Twine, N. A.; Bauer, D. C.

10.1101/2022.04.06.487300 — bioinformatics — Posted on 2023-06-15

2170 Large Scale Foundation Model on Single-cell Transcriptomics

Hao, M.; Gong, J.; Zeng, X.; Liu, C.; Guo, Y.; Cheng, X.; Wang, T.; Ma, J.; Song, L.; Zhang, X.

10.1101/2023.05.29.542705 — bioinformatics — Posted on 2023-06-15

2171 Centrifugal Gel Crushing for Gel-based Proteome Analysis

Nishida, H.; Kanao, E.; Ishihama, Y.

10.1101/2023.06.15.545122 — biochemistry — Posted on 2023-06-15

2172 A novel sorting signal for RNA packaging into small extracellular vesicles

Oka, Y.; Tanaka, K.; Kawasaki, Y.

10.1101/2023.06.08.544286 — cell biology — Posted on 2023-06-15

2173 Global transcriptome analysis reveals Salmonella Typhimurium employs the nitrate-dependent anaerobic pathway to combat bile stress

Singh, M.; Chandra, D.; Jagdish, S.; Nandi, D.

10.1101/2023.06.15.545048 — microbiology — Posted on 2023-06-15

2174 Evolution of Shewanella oneidensis MR-1 in competition with Citrobacter freundii

Zhao, B.; Chen, G.; Chen, W.; Xiao, Y.

10.1101/2023.06.15.545074 — microbiology — Posted on 2023-06-15

2175 Partial genome characterization of a novel potentially zoonotic parapoxvirus in a horse, Finland

Virtanen, J.; Hautaniemi, M.; Dutra, L.; Pljusnin, I.; Hautala, K.; Smura, T.; Vapalahti, O.; Sironen, T.; Kant, R.; Kinnunen, P. M.

10.1101/2023.03.21.533517 — microbiology — Posted on 2023-06-15

2176 Improved RNA stability estimation through Bayesian modeling reveals most bacterial transcripts have sub-minute half-lives

Jenniches, L.; Michaux, C.; Reichardt, S.; Vogel, J.; Westermann, A. J.; Barquist, L.

10.1101/2023.06.15.545072 — microbiology — Posted on 2023-06-15

2177 The transcriptional regulator EarA and intergenic terminator sequences modulate archaellation in Pyrococcus furiosus

Stoeckl, R.; Nissl, L.; Reichelt, R.; Rachel, R.; Grohmann, D.; Gruenberger, F.

10.1101/2023.06.15.545098 — microbiology — Posted on 2023-06-15

2178 Evolution of Shewanella oneidensis MR-1 in competition with Citrobacter freundii

Zhao, B.; Chen, G.; Chen, W.; Xiao, Y.

10.1101/2023.06.15.545074 — microbiology — Posted on 2023-06-15

2179 Hypermethylation is associated with increased age in almond (Prunus dulcis D.A. Webb) accessions

D'Amico-Willman, K. M.; Niederhuth, C.; Sovic, M.; Anderson, E. S.; Gradziel, T. M.; Fresnedo Ramirez, J.

10.1101/2021.05.02.442365 — plant biology — Posted on 2023-06-15

2180 Two subtypes of GTPase-activating proteins coordinate tip growth and cell size regulation in Physcomitrium patens

Ruan, J.; Lai, L.; Ou, H.; Yi, P.

10.1101/2023.06.15.545175 — plant biology — Posted on 2023-06-15

2181 Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

Nakonechnaya, T. O.; Moltedo, B.; Putintseva, E. V.; Leyn, S.; Bolotin, D. A.; Britanova, O. V.; Shugay, M.; Rudensky, A. Y.; Chudakov, D. M.

10.1101/2023.06.15.544726 — immunology — Posted on 2023-06-15

2182 TCRpcDist: Estimating TCR physico-chemical similarity to analyze repertoires and predict specificities

Perez Gomes, M. A. S.; Chiffelle, J.; Bobisse, S.; Mayol-Rullan, F.; Arnaud, M.; Sauvage, C.; Coukos, G.; Harari, A.; Zoete, V.

10.1101/2023.06.15.545077 — immunology — Posted on 2023-06-15

2183 LAG3 regulates antibody responses in a murine model of kidney transplantation

Nicosia, M.; Fan, R.; Lee, J.; Gorbacheva, V.; Valenzuela, J. I.; Yamamoto, Y.; Beavers, A.; Dvorina, N.; Chuluyan, E.; Araki, M.; Baldwin, W.; Fairchild, R. L.; Min, B.; Valujskikh, A.

10.1101/2022.01.31.478518 — immunology — Posted on 2023-06-15

2184 CETP inhibitor evacetrapib enters mouse brain tissue

Phenix, J.; Cote, J.; Dieme, D.; Recinto, S. J.; Oestereich, F.; Efrem, S.; Haddad, S.; Bouchard, M.; Munter, L. M.

10.1101/2023.02.21.529381 — pharmacology and toxicology — Posted on 2023-06-15

2185 ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers

Martin-Vega, A.; Earnest, S.; Augustyn, A.; Wichaidit, C.; Gazdar, A. F.; Girard, L.; Peyton, M.; Kollipara, R. K.; Minna, J. D.; Johnson, J. E.; Cobb, M. H.

10.1101/2023.06.15.545148 — cancer biology — Posted on 2023-06-15

2186 Machine-learning-based motion tracking revealed the inverse correlation between adhesivity and surface motility of the leptospirosis spirochete

Abe, K.; Koizumi, N.; Nakamura, S.

10.1101/2023.06.15.545171 — biophysics — Posted on 2023-06-15

2187 Platelet-Localized ST6Gal1 Does Not Impact IgG Sialylation

Glendenning, L. M.; Zhou, J. Y.; Kukan, E. N.; Gao, C.; Cummings, R. D.; Joshi, S.; Whiteheart, S. W.; Cobb, B. A.

10.1101/2023.06.15.545133 — immunology — Posted on 2023-06-15

2188 Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV

Matveev, V. A.; Mihelic, E. Z.; Benko, E.; Budylowski, P.; Grocott, S.; Lee, T.; Korosec, C. S.; Colwill, K.; Stephenson, H.; Law, R.; Ward, L. A.; Sheikh-Mohamed, S.; Mailhot, G.; Delgado-Brand, M.; Pasculescu, A.; Wang, J. H.; Qi, F.; Tursun, T.; Kardava, L.; Chau, S.; Samaan, P.; Imran, A.; Copertino, D. C.; Chao, G.; Choi, Y.; Reinhard, R. J.; Kaul, R.; Heffernan, J. M.; Jones, R. B.; Chun, T.-W.; Moir, S.; Singer, J.; Gommerman, J.; Gingras, A.-C.; Kovacs, C.; Ostrowski, M.

10.1101/2023.06.14.544834 — immunology — Posted on 2023-06-15

2189 Microbial dynamics inference at ecosystem-scale

Gibson, T. E.; Kim, Y.; Acharya, S.; Kaplan, D. E.; DiBenedetto, N.; Lavin, R.; Berger, B.; Allegretti, J. R.; Bry, L.; Gerber, G. K.

10.1101/2021.12.14.469105 — systems biology — Posted on 2023-06-15

2190 Kinetic modeling of leucine-mediated signaling and protein metabolism in human skeletal muscle

McColl, T. J.; Clarke, D. C.

10.1101/2023.06.10.544441 — systems biology — Posted on 2023-06-15

2191 FLOWERING LOCUS C drives delayed flowering in Arabidopsis grown and selected at elevated CO2

Henderson-Carter, A. L.; Kinmonth-Schultz, H.; Hileman, L.; Ward, J. K.

10.1101/2023.06.15.545149 — plant biology — Posted on 2023-06-15

2192 Two subtypes of GTPase-activating proteins coordinate tip growth and cell size regulation in Physcomitrium patens

Ruan, J.; Lai, L.; Ou, H.; Yi, P.

10.1101/2023.06.15.545175 — plant biology — Posted on 2023-06-15

2193 Disentangling the cascading effects of Grapevine Red Blotch Virus infection on vine physiology

Copp, C. R.; DeShields, J. B.; Kar, S.; Kirk, C.; Clark, R.; Stowasser, M.; KC, A. N.; Levin, A.

10.1101/2023.06.15.545163 — plant biology — Posted on 2023-06-15

2194 β Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes Risk

Syed, F.; Krishnan, P.; Chang, G.; Langlais, S. R.; Hati, S.; Yamada, K.; Lam, A. K.; Talware, S.; Liu, X.; Sardar, R.; Liu, J.; Mirmira, R. G.; Evans-Molina, C.

10.1101/2023.06.15.545170 — physiology — Posted on 2023-06-15

2195 Sperm Toolbox - A selection of small molecules to study human spermatozoa

Gruber, F. S.; Richardson, A.; Johnston, Z. C.; Myles, R.; Norcross, N.; Day, D.; Georgiou, I.; Sesma Sanz, L.; Wilson, C.; Read, K. D.; Martins da Silva, S.; Barratt, C. L.; Gilbert, I. H.; Swedlow, J. R.

10.1101/2023.05.02.539126 — pharmacology and toxicology — Posted on 2023-06-15

2196 Uncovering Alterations in Cancer Epigenetics via Trans-Dimensional Markov Chain Monte Carlo and Hidden Markov Models

Shokoohi, F.; Khaniki, S. H.

10.1101/2023.06.15.545168 — bioinformatics — Posted on 2023-06-15

2197 Exploring phytoconstituents of Juglans regia to treat cervical cancer using integrative Bioinformatics

Dua, R.; Ahmad, I.; Bhardwaj, T.; Somvanshi, P.

10.1101/2023.06.15.545164 — bioinformatics — Posted on 2023-06-15

2198 High-Resolution Additive Manufacturing of a Biodegradable Elastomer with a Low-Cost LCD 3D Printer

Karamzadeh, V.; Shen, M.; Ravanbakhsh, H.; Kashani, A. S.; Savoji, H.; Radisic, M.; Juncker, D.

10.1101/2023.06.15.545079 — bioengineering — Posted on 2023-06-15

2199 Pneumatically Controlled Non-Equibiaxial Cell Stretching Device with Live-cell Imaging

Wang, J.; Chatterjee, A.; Zigan, C. M.; Alborn, M. J.; Chan, D.; Chortos, A.

10.1101/2023.06.15.545174 — bioengineering — Posted on 2023-06-15

2200 Injectable ventral spinal stimulator evokes programmable and biomimetic hindlimb motion

LIN, D.; Lee, J. M.; Wang, C.; Park, H.-G.; Lieber, C. M.

10.1101/2023.06.15.545178 — bioengineering — Posted on 2023-06-15

2201 Evaluating power to detect recurrent selective sweeps under increasingly realistic evolutionary null models

Soni, V.; Johri, P.; Jensen, J. D.

10.1101/2023.06.15.545166 — genomics — Posted on 2023-06-15

2202 Evaluating cancer cell line and patient-derived xenograft recapitulation of tumor and non-diseasedtissue gene expression profiles in silico

Williams, A. S.; Wilk, E. J.; Fisher, J. L.; Lasseigne, B. N.

10.1101/2023.04.11.536431 — genomics — Posted on 2023-06-15

2203 Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms

Zheng, Y.; Sun, C.; Zhang, X.; Ruzycki, P.; Chen, S.

10.1101/2023.02.01.526652 — genetics — Posted on 2023-06-15

2204 Modelling Human Post-Implantation Development via Extra-Embryonic Niche Engineering

Hislop, J. J.; Alavi, A.; Song, Q.; Schoenberger, R. L.; Keshavarz F., K.; LeGraw, R.; Velazquez, J. J.; Mokhtari, T.; Taheri, M. N.; Rytel, M.; de Sousa Lopes, S. M. C.; Watkins, S. C.; Stolz, D. B.; Kiani, S.; Sozen, B.; Bar-Joseph, Z.; Ebrahimkhani, M.

10.1101/2023.06.15.545118 — developmental biology — Posted on 2023-06-15

2205 Characterization of genetic and molecular tools for studying the endogenous expression of Lactate dehydrogenase in Drosophila melanogaster

Rai, M.; Carter, S. M.; Shefali, S. A.; Chawla, G.; Tennessen, J. M.

10.1101/2023.06.15.545165 — developmental biology — Posted on 2023-06-15

2206 Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity

Xu, C.; Ramos, T. B.; Rogers, E. M.; Reiser, M. B.; Doe, C. Q.

10.1101/2021.10.01.462699 — developmental biology — Posted on 2023-06-15

2207 Myosin 10 uses its MyTH4 and FERM domains differentially to support two aspects of spindle pole biology required for mitotic spindle bipolarity

Yim, Y.-I.; Pedrosa, A.; Wu, X.; Chinthalapudi, K.; Cheney, R. E.; Hammer, J.

10.1101/2023.06.15.545002 — cell biology — Posted on 2023-06-15

2208 An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity

Ader, N. R.; Chen, L.; Surovtsev, I. V.; Chadwick, W. L.; Rodriguez, E. C.; King, M. C.; Lusk, C. P.

10.1101/2022.12.12.520126 — cell biology — Posted on 2023-06-15

2209 Temporal segmentation and 'look ahead' simulation: Physical events structure visual perception of intuitive physics

Yates, T. S.; Yasuda, S.; Yildirim, I.

10.1101/2023.06.14.544968 — neuroscience — Posted on 2023-06-15

2210 Displacement of extracellular chloride by sulfated glycosaminoglycans of the brain extracellular matrix

Normoyle, K. P.; Lillis, K. P.; Egawa, K.; McNally, M. A.; Staley, K. J.

10.1101/2022.12.28.522113 — neuroscience — Posted on 2023-06-15

2211 Direct interhemispheric cortical communication via thalamic commissures: a new white-matter pathway in the primate brain

Szczupak, D.; Schaeffer, D.; Tian, X.; Choi, S.-H.; Cheng, F.; Iack, P. M.; Campos, V. P.; Mayo, P. J.; Patsch, J.; Mitter, C.; Haboosheh, A.; Vieira, M.; Kasprian, G.; Lent, R.; Moll, F. T.; Silva, A. C.

10.1101/2023.06.15.545128 — neuroscience — Posted on 2023-06-15

2212 Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice.

Delignat-Lavaud, B.; Kano, J.; Ducrot, C.; Masse, I.; Mukherjee, S.; Giguere, N.; Moquin, L.; Levesque, C.; Burke, S.; Bourque, M.-J.; Tchung, A.; Rosa-Neto, P.; Levesque, D.; De Beaumont, L.; Trudeau, L.-E.

10.1101/2021.09.15.460511 — neuroscience — Posted on 2023-06-15

2213 Novel Diazirine Photoprobes for the Identification of Vancomycin-Binding Proteins

Rotsides, P.; Lee, P. J.; Webber, N.; Grasty, K. C.; Beld, J.; Loll, P. J.

10.1101/2023.06.15.545140 — biochemistry — Posted on 2023-06-15

2214 Revealing Chloroquine's Antimalarial Mechanism: The Suppression of Nucleation Events during Heme to Hemozoin Transformation

Singh, R.; Singh, R.; Srihari, V.; Makde, R. D.

10.1101/2023.06.15.545078 — biochemistry — Posted on 2023-06-15

2215 Herpes-like viral elements and universal subtelomeric ribosomal RNA genes in a chromosome-scale thraustochytrid genome assembly

Collier, J. L.; Rest, J. S.; Gallot-Lavallee, L.; Lavington, E.; Kuo, A.; Jenkins, J. W.; Plott, C.; Pangilinan, J.; Daum, C.; Grigoriev, I. V.; Filloramo, G. V.; Novak Vanclova, A. G.; Archibald, J. M.

10.1101/2023.06.15.545109 — genomics — Posted on 2023-06-15

2216 Evolution of ion channels in cetaceans a natural experiment in the tree of life

Uribe, C.; Nery, M.; Zavala, K.; Mardones, G.; Riadi, G.; Opazo, J.

10.1101/2023.06.15.545160 — evolutionary biology — Posted on 2023-06-15

2217 Flexible coding schemes in dorsomedial prefrontal cortex underlie decision-making during delay discounting

White, S. M.; Morningstar, M. D.; De Falco, E.; Linsenbardt, D. N.; Parks, M. A.; Ma, B.; Czachowski, C. L.; Lapish, C. C.

10.1101/2023.06.15.545101 — neuroscience — Posted on 2023-06-15

2218 Digital-robotic markers for hallucinations in Parkinson's disease

Albert, L. P.; Potheegadoo, J.; Herbelin, B.; Bernasconi, F.; Blanke, O.

10.1101/2023.06.14.544929 — neuroscience — Posted on 2023-06-15

2219 Regulatory properties of transcription factors with diverse mechanistic function

Ali, M. Z.; Guharajan, S.; Parisutham, V.; Brewster, R. C.

10.1101/2023.06.15.545127 — systems biology — Posted on 2023-06-15

2220 Prolonged exposure to hypergravity increases number and size of cells and enhances lignin deposition in the stem of Arabidopsis thaliana (L.) Heynh.

Shinohara, H.; Muramoto, M.; Tamaoki, D.; Kamachi, H.; Inoue, H.; Kume, A.; Karahara, I.

10.1101/2023.06.15.545094 — plant biology — Posted on 2023-06-15

2221 DIRECT REGULATION OF THE VOLTAGE-SENSING DOMAIN OF HCN CHANNELS BY MEMBRANE LIPID COMPARTMENTALIZATION

Handlin, L. J.; Dai, G.

10.1101/2023.06.15.545112 — physiology — Posted on 2023-06-15

2222 Local, Quantitative Morphometry of Fibroproliferative Lung Injury using Laminin.

Cox, B.; HANNAN, R.; Batrash, N.; Sturek, J.

10.1101/2023.06.15.545119 — pathology — Posted on 2023-06-15

2223 MEK1/2-Targeting PROTACs Promote the Collateral Degradation of CRAF in KRAS Mutant Cells

Herrera-Montavez, C.; Kurimchak, A. M.; Hu, X.; Hu, J.; Jin, J.; Duncan, J. S.

10.1101/2023.06.15.545136 — cancer biology — Posted on 2023-06-15

2224 Mechanism of negative μ-opioid receptor modulation by sodium ions

Thomson, N. J.; Zachariae, U.

10.1101/2023.06.15.545124 — biophysics — Posted on 2023-06-15

2225 Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo

Mendoza, J.; Purchal, M.; Yamada, K.; Koutmos, M.

10.1101/2023.06.15.544998 — biochemistry — Posted on 2023-06-15

2226 Machine learning and phylogenetic models identify predictors of genetic variation in Neotropical amphibians

Amador, L.; Arroyo-Torres, I.; Barrow, L. N.

10.1101/2023.06.15.545105 — evolutionary biology — Posted on 2023-06-15

2227 Transgene directed induction of a stem cell-derived human embryo model

Weatherbee, B. A. T.; Gantner, C. W.; Daza, R. M.; Hamazaki, N.; Iwamoto-Stohl, L. K.; Shendure, J.; Zernicka-Goetz, M.

10.1101/2023.06.15.545082 — developmental biology — Posted on 2023-06-15

2228 Localization of PPM1H phosphatase tunes Parkinsons disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis

Yeshaw, W. M.; Adhikari, A.; Chiang, C. Y.; Dhekne, H. S.; Wawro, P. S.; Pfeffer, S. R.

10.1101/2023.06.15.545139 — cell biology — Posted on 2023-06-15

2229 Demystifying the Visual Word Form Area: Precision fMRI of Visual, Linguistic, and Attentional Properties of Ventral Temporal Cortex

Li, J.; Hiersche, K.; Saygin, Z. M.

10.1101/2023.06.15.544824 — neuroscience — Posted on 2023-06-15

2230 Sucrose overconsumption impairs feeding circuit dynamics and promotes palatable food intake

Beutler, L. R.; Lorch, C. M.; Hayes, N. W.; Xia, J. L.; Fleps, S. W.; McMorrow, H. E.; Province, H. S.; Frydman, J. A.; Parker, J. G.

10.1101/2023.06.15.545110 — neuroscience — Posted on 2023-06-15

2231 Inhibition of Retinoic Acid Signaling in Proximal Tubular Epithelial cells Protects against Acute Kidney Injury by Enhancing Kim-1-dependent Efferocytosis

Yang, M.; Lopez, L. N.; Brewer, M.; Delgado, R. D.; Menshikh, A. A.; Clouthier, K. A.; Zhu, Y.; Vanichapol, T.; Yang, H.; Harris, R.; Gewin, L.; Brooks, C. R.; Davidson, A.; de Caestecker, M.

10.1101/2023.06.15.545113 — pathology — Posted on 2023-06-15

2232 Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly

Benning, F. M. C.; Jenni, S.; Garcia, C. Y.; Nguyen, T. H.; Zhang, X.; Chao, L. H.

10.1101/2023.06.15.545104 — biophysics — Posted on 2023-06-15

2233 A brand-new clustering method and analysis system designed for revealing the truth of the high-dimension large data deciphered the complex composition structure of human brain endothelial cells from single- cell RNA sequence data

wei, b.

10.1101/2023.06.14.544789 — bioinformatics — Posted on 2023-06-15

2234 AddBiomechanics: Automating model scaling, inverse kinematics, and inverse dynamics from human motion data through sequential optimization

Werling, K.; Bianco, N. A.; Raitor, M.; Stingel, J.; Hicks, J. L.; Collins, S. H.; Delp, S.; Liu, C. K.

10.1101/2023.06.15.545116 — bioengineering — Posted on 2023-06-15

2235 The critical role of spatio-temporal control in combinatorial chemo- and magnetic hyperthermia thermo-therapy: 'the where', 'the how' and 'the when'

Garcia-Hevia, L.; Magalhaes, A. P.; Genicio, N.; Casafont, I.; Costa da Silva, M.; Lopez Fanarraga, M.; Banobre-Lopez, M.; Gallo, J.

10.1101/2023.06.15.545102 — biochemistry — Posted on 2023-06-15

2236 Centrifugal Gel Crushing for Gel-based Proteome Analysis

Nishida, H.; Kanao, E.; Ishihama, Y.

10.1101/2023.06.15.545122 — biochemistry — Posted on 2023-06-15

2237 Inclusion of glycopeptides in hydrogen/deuterium exchange mass spectrometry analysis of SARS-CoV-2 spike ectodomain provides increased sequence coverage

Haynes, C. A.; Keppel, T. R.; Mekonnen, B.; Osman, S. H.; Zhou, Y.; Woolfitt, A. R.; Baudys, J.; Barr, J. R.; Wang, D.

10.1101/2023.06.14.544985 — biochemistry — Posted on 2023-06-15

2238 Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain

Cruz, S. J.; Burendei, B.; Lee, W.-H.; Ward, A.

10.1101/2023.06.15.545135 — biochemistry — Posted on 2023-06-15

2239 Calculating and applying pathogen mutational spectra using MutTui

Ruis, C.; Tonkin-Hill, G.; Floto, R. A.; Parkhill, J.

10.1101/2023.06.15.545111 — genomics — Posted on 2023-06-15

2240 WFIKKN2 is a bifunctional axon guidance cue that signals through divergent DCC family receptors

Nickerson, K. R.; Tom, I.; Cortes, E.; Abolafia, J. R.; Özkan, E.; Gonzalez, L. C.; Jaworski, A.

10.1101/2023.06.15.544950 — developmental biology — Posted on 2023-06-15

2241 Gastruloid-derived Primordial Germ Cell-like Cells (Gld-PGCLCs) develop dynamically within integrated tissues

Cooke, C. B.; Barrington, C.; Baillie-Benson, P.; Nichols, J.; Moris, N.

10.1101/2023.06.15.545059 — developmental biology — Posted on 2023-06-15

2242 Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types

Xu, C.; Ramos, T. B.; Marshall, O.; Doe, C. Q.

10.1101/2023.06.15.545141 — developmental biology — Posted on 2023-06-15

2243 Spindle Chirp and other Sleep Oscillatory Features in Young Children with Autism

Cumming, D.; Kozhemiako, N.; Thurm, A.; Farmer, C.; Purcell, S.; Buckley, A.

10.1101/2023.06.15.545095 — neuroscience — Posted on 2023-06-15

2244 A novel 4D fMRI clustering technique to examine event-related spatiotemporal dynamics of face processing in naturalistic stimuli

Ekstrand, C.

10.1101/2023.06.15.545143 — neuroscience — Posted on 2023-06-15

2245 SoyDNGP: A Web-Accessible Deep Learning Framework for Genomic Prediction in Soybean Breeding

Gao, P.; Zhao, H.; Luo, Z.; Lin, Y.; Li, Y.; Kong, F.; Fang, C.; Wang, X.

10.1101/2023.06.15.545107 — plant biology — Posted on 2023-06-15

2246 Acute exposure of fruit bats to low concentrations of heavy metals affects oxidative stress markers

Destro, A. L. F.; Alves, T. S.; Dias, F. R.; Goncalves, R. V.; Oliveira, J. M.; Oliveira, L. L.; Freitas, M. B.

10.1101/2023.06.15.545099 — pharmacology and toxicology — Posted on 2023-06-15

2247 Predicting cued and oddball visual search performance from neural representational similarity

Yeh, L.-C.; Thorat, S.; Peelen, M. V.

10.1101/2023.06.15.545065 — neuroscience — Posted on 2023-06-15

2248 NG2 Glia Reprogramming Induces Robust Axonal Regeneration After Spinal Cord Injury

Tai, W.; Du, X.; Chen, C.; Xu, X.-M.; Zhang, C.-L.; Wu, W.

10.1101/2023.06.14.544792 — neuroscience — Posted on 2023-06-15

2249 Meta-analysis and Open-source Database for In Vivo Brain Magnetic Resonance Spectroscopy Studies of Health and Disease

Gudmundson, A. T.; Koo, A.; Virovka, A.; Amirault, A. L.; Soo, M.; Cho, J. H.; Oeltzschner, G. T.; Edden, R. A.; Stark, C. E.

10.1101/2023.02.10.528046 — neuroscience — Posted on 2023-06-15

2250 Cortical neurons obtained from patient-derived GNAO1 iPSCs show altered differentiation and functional properties

Benedetti, M. C.; D'Andrea, T.; Colantoni, A.; de Turris, V.; Boussadia, Z.; Pepponi, R.; Whye, D.; Buttermore, E. D.; Tartaglia, G. G.; Musayev, I.; Martinelli, S.; Fucile, S.; Rosa, A.

10.1101/2023.06.15.545051 — neuroscience — Posted on 2023-06-15

2251 Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region

Morales-Gregorio, A.; Kurth, A. C.; Ito, J.; Kleinjohann, A.; Barthelemy, F. V.; Brochier, T.; Grün, S.; van Albada, S. J.

10.1101/2023.06.14.544966 — neuroscience — Posted on 2023-06-15

2252 17α-estradiol Alleviates High-Fat Diet-Induced Inflammatory and Metabolic Dysfunction in Skeletal Muscle of Male and Female Mice

Bubak, M. P.; Mann, S. N.; Borowik, A. K.; Pranay, A.; Batushansky, A.; Mondal, S. A.; Diodge, S. M.; Davidyan, A.; Szczygiel, M. M.; Pellor, R. F.; Rigsby, S.; Broomfield, M. E.; Lacy, C. I.; Rice, H. C.; Stout, M. B.; Miller, B. F.

10.1101/2023.05.30.542870 — physiology — Posted on 2023-06-15

2253 Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A.

Koesters, A. G.; Rich, M. M.; Engisch, K. L.

10.1101/2023.06.14.544980 — neuroscience — Posted on 2023-06-15

2254 Dopamine D1-like receptors modulate synchronized oscillations in the hippocampal-prefrontal-amygdala circuit in contextual fear

Stubbendorff, C.; Hale, E.; Bast, T.; Cassaday, H. J.; Martin, S. J.; Suwansawang, S.; Halliday, D. M.; Stevenson, C. W.

10.1101/2023.06.15.545080 — neuroscience — Posted on 2023-06-15

2255 Second-order effects of chemotherapy pharmacodynamics and pharmacokinetics on tumor regression and cachexia

Pierik, L.; McDonald, P.; Anderson, A. R. A.; West, J.

10.1101/2023.06.14.544974 — cancer biology — Posted on 2023-06-15

2256 Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response

Theusch, E.; Ting, F. Y.; Qin, Y.; Stevens, K.; Naidoo, D.; King, S. M.; Yang, N.; Orr, J.; Han, B. Y.; Cyster, J. G.; Chen, Y.-D. I.; Rotter, J. I.; Krauss, R. M.; Medina, M. W.

10.1101/2023.06.14.544860 — genomics — Posted on 2023-06-15

2257 Analysis of follow-up data in large biobank cohorts: a review of methodology

Mändul, M.; Kolde, A.; Käärik, M.; Möls, M.; Fischer, K.

10.1101/2023.06.14.542699 — genomics — Posted on 2023-06-15

2258 Common molecular signatures between coronavirus infection and Alzheimer's disease reveal targets for drug development

Abyadeh, M.; Yadav, V.; Kaya, A.

10.1101/2023.06.14.544970 — neuroscience — Posted on 2023-06-15

2259 Universal Dynamic Fitting of Magnetic Resonance Spectroscopy

Clarke, W. T.; Ligneul, C.; Cottaar, M.; Ip, I. B.; Jbabdi, S.

10.1101/2023.06.15.544935 — neuroscience — Posted on 2023-06-15

2260 Discovery and engineering of hypercompact epigenetic modulators for durable gene activation

Carosso, G. A.; Yeo, R. W.; Gainous, T. B.; Jawaid, Z.; Yang, X.; Cutillas, V.; Qi, L. S.; Daley, T. P.; Hart, D. O.

10.1101/2023.06.02.543492 — synthetic biology — Posted on 2023-06-15

2261 A survey of CIN measures across mechanistic models

Lynch, A. R.; Bradford, S.; Zhou, A. S.; Oxendine, K.; Henderson, L.; Horner, V. L.; Weaver, B. A.; Burkard, M. E.

10.1101/2023.06.15.544840 — cancer biology — Posted on 2023-06-15

2262 Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells

Magnani, C. F.; Myburgh, R.; Brunn, S.; Chambovey, M.; Ponzo, M.; Volta, L.; Pellegrino, C.; Pascolo, S.; Miskey, C.; Ivics, Z.; Shizuru, J. A.; Neri, D.; Manz, M. G.

10.1101/2023.06.15.544946 — cancer biology — Posted on 2023-06-15

2263 scATAnno: Automated Cell Type Annotation for single-cell ATAC Sequencing Data

Jiang, Y.; Hu, Z.; Jiang, J.; Zhu, A.; Zhang, Y.; Lynch, A. W.; Xie, Y.; Li, R.; Zhou, N.; Meyer, C. A.; Cejas, P.; Brown, M.; Long, H. W.; Qiu, X.

10.1101/2023.06.01.543296 — bioinformatics — Posted on 2023-06-15

2264 Pan-genome analysis highlights the role of structural variation in the evolution and environmental adaptation of Asian honeybees

Li, Y.; Yao, J.; Sang, H.; Wang, Q.; Su, L.; Zhao, X.; Xia, Z.; Wang, F.; Wang, K.; Lou, D.; Wang, G.; Waterhouse, R. M.; Wang, H.; Luo, S.; Sun, C.

10.1101/2023.06.15.545041 — genomics — Posted on 2023-06-15

2265 scAbsolute: Measuring single-cell ploidy and replication status

Schneider, M. P.; Cullen, A.; Pangonyte, J.; Skelton, J.; Major, H.; Van Oudenhove, E.; Garcia, M. J.; Chaves-Urbano, B.; Piskorz, A. M.; Brenton, J. D.; Macintyre, G.; Markowetz, F.

10.1101/2022.11.14.516440 — genomics — Posted on 2023-06-15

2266 nnSVG for the scalable identification of spatially variable genes using nearest-neighbor Gaussian processes

Weber, L. M.; Saha, A.; Datta, A.; Hansen, K. D.; Hicks, S. C.

10.1101/2022.05.16.492124 — genomics — Posted on 2023-06-15

2267 Sequence and epigenetic landscapes of active and silenced nucleolus organizers in Arabidopsis

Fultz, D.; McKinlay, A.; Enganti, R.; Pikaard, C.

10.1101/2023.06.07.544131 — genomics — Posted on 2023-06-15

2268 Sexual antagonism evolves when autosomes influence offspring sex ratio

Sloat, S. A.; Rockman, M. V.

10.1101/2023.06.14.544982 — evolutionary biology — Posted on 2023-06-15

2269 Structural organisation of perisomatic inhibition in the mouse medial prefrontal cortex

Nagy-Pal, P.; Veres, J.; Fekete, Z.; Karlocai, M. R.; Weisz, F.; Barabas, B.; Reeb, Z.; Hajos, N.

10.1101/2023.06.14.545032 — neuroscience — Posted on 2023-06-15

2270 Learning predictive signals within a local recurrent circuit

Asabuki, T.; Gillon, C. J.; Clopath, C.

10.1101/2023.06.15.545081 — neuroscience — Posted on 2023-06-15

2271 A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

Chan, M.; Sahakyan, H.; Eldstrom, J.; Sastre, D.; Wang, Y.; Dou, Y.; Pourrier, M.; Vardanian, V.; Fedida, D.

10.1101/2023.02.27.530167 — pharmacology and toxicology — Posted on 2023-06-15

2272 HCCDB v2.0: Decompose the Expression Variations by Single-cell RNA-seq and Spatial Transcriptomics in HCC

Jiang, Z.; Wu, Y.; Miao, Y.; Deng, K.; Yang, F.; Xu, S.; Wang, Y.; You, R.; Zhang, L.; Fan, Y.; Guo, W.; Lian, Q.; Chen, L.; Zhang, X.; Zheng, Y.; Gu, J.

10.1101/2023.06.15.545045 — cancer biology — Posted on 2023-06-15

2273 Targeting BTN2A1 enhances Vγ9Vδ2 T cell effector functions and triggers tumor cells pyroptosis

le Floch, A. C.; Imbert, C.; Boucherit, N.; Gorvel, L.; Fattori, S.; Orlanducci, F.; Le Roy, A.; Archetti, L.; Crescence, L.; Panicot-Dubois, L.; Dubois, C.; Vey, N.; Briantais, A.; Anastasio, A.; Cano, C.; Guittard, G.; Frechin, M.; Olive, D.

10.1101/2023.06.15.545049 — cancer biology — Posted on 2023-06-15

2274 Kinetics of radiation-induced DNA double-strand breaks through coarse-grained simulations

Micheloni, M.; Petrolli, L.; Lattanzi, G.; Potestio, R.

10.1101/2022.07.03.498607 — biophysics — Posted on 2023-06-15

2275 The Free Lunch is not over yet - Systematic Exploration of Numerical Thresholds in Phylogenetic Inference

Haag, J.; Hübner, L.; Kozlov, A. M.; Stamatakis, A.

10.1101/2022.07.13.499893 — bioinformatics — Posted on 2023-06-15

2276 Interstage flow matrices: population statistic derived from matrix population models

Yokomizo, H.; Fukaya, K.; Lambrinos, J. G.; Kawai, Y.; Takada, T.

10.1101/2023.06.14.545022 — ecology — Posted on 2023-06-15

2277 Comprehensive Characterization and Global Transcriptome Analyses of Human Fetal Liver Terminal Erythropoiesis

Han, Y.; Wang, S.; Wang, Y.; Huang, Y.; Gao, C.; Guo, X.; Chen, L.; Zhao, H.; An, X.

10.1101/2023.06.15.545026 — cell biology — Posted on 2023-06-15

2278 A window to the brain: ultrasound imaging of human neural activity through a permanent acoustic window

Rabut, C.; Norman, S. L.; Griggs, W. S.; Russin, J. J.; Jann, K.; Christopoulos, V.; Liu, C.; Andersen, R. A.; Shapiro, M. G.

10.1101/2023.06.14.544094 — neuroscience — Posted on 2023-06-15

2279 Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior

Qi, L.; Iskols, M.; Handler, A.; Ginty, D. D.

10.1101/2023.06.14.545006 — neuroscience — Posted on 2023-06-15

2280 Contact toxicity, antifeedant activity and oviposition preference of osthole against agricultural pests

Dong, F.; Chen, X.; Men, X.; Li, Z.; Kong, Y.; Yuan, Y.; Ge, F.

10.1101/2023.06.15.545046 — zoology — Posted on 2023-06-15

2281 JMnorm: a novel Joint Multi-feature normalization method for integrative and comparative epigenomics

Xiang, G.; Guo, Y.; Bumcrot, D.; Sigova, A.

10.1101/2023.06.14.545004 — systems biology — Posted on 2023-06-15

2282 Untargeted metabolomics reveals PTI-associated metabolites in cultivated tomato

Munoz Hoyos, L.; Wan, P. A.; Meng, C.; Kleigrewe, K.; Dawid, C.; Hückelhoven, R.; Stam, R.

10.1101/2023.06.15.544816 — plant biology — Posted on 2023-06-15

2283 Transcriptional analysis in multiple barley varieties identifies signatures of waterlogging response

Miricescu, A.; Brazel, A. J.; Beegan, J.; Wellmer, F.; Graciet, E.

10.1101/2022.11.26.518028 — plant biology — Posted on 2023-06-15

2284 A peptide that regulates metalation of the Arabidopsis ethylene receptor.

Mudge, A. M.; Mehdi, S.; Michaels, W. E.; Oroza-Puente, B.; Shen, W.; Sadanandom, A.; Hetherington, F. M.; Hoppen, C.; Uzun, B.; Groth, G.; Topping, J. F.; Robinson, N. J.; Lindsey, K.

10.1101/2023.06.15.545071 — plant biology — Posted on 2023-06-15

2285 Characterization of the genetic composition and establishment of a core collection for the INERA Robusta coffee (Coffea canephora) field genebank from the Democratic Republic of the Congo

Verleysen, L.; Bollen, R.; Kambale, J. L.; Tshimi, E.; Ntumba Katshela, B.; Depecker, J.; Poncet, V.; Assumani, D. M.; Vandelook, F.; Stoffelen, P.; Honnay, O.; Ruttink, T.

10.1101/2023.06.15.544964 — plant biology — Posted on 2023-06-15

2286 The memory of airway epithelium damage in smokers and COPD patients

Carlier, F. M.; Detry, B.; Lecocq, M.; Collin, A. M.; Plante-Bordeneuve, T.; Verleden, S. E.; Delos, M.; Rondelet, B.; Janssens, W.; Ambroise, J.; Vanaudenaerde, B. M.; Gohy, S. T.; Pilette, C.

10.1101/2021.04.21.439437 — pathology — Posted on 2023-06-15

2287 Tertiary structure and conformational dynamics of the anti-amyloidogenic chaperone DNAJB6b at atomistic resolution

Adupa, V.; Ustyantseva, E.; Kampinga, H. H.; Onck, P. R.

10.1101/2023.06.15.545060 — biophysics — Posted on 2023-06-15

2288 VIGA: an one-stop tool for eukaryotic Virus Identification and Genome Assembly from next-generation-sequencing data

Fu, P.; Wu, Y.; Zhang, Z.; Qiu, Y.; Wang, Y.; Peng, Y.

10.1101/2023.06.14.545025 — bioinformatics — Posted on 2023-06-15

2289 Prediction of virus-host association using protein language models and multiple instance learning

Liu, D.; Young, F.; Robertson, D. L.; Yuan, K.

10.1101/2023.04.07.536023 — bioinformatics — Posted on 2023-06-15

2290 A generalized approach to genetic drift and its applications -- I. An example of the evolution of ribosomal RNA genes

Wang, X.; Ruan, Y.; Zhang, L.; Chen, X.; Shi, Z.; Wen, H.; Wu, C.-I.

10.1101/2023.06.14.545040 — evolutionary biology — Posted on 2023-06-15

2291 Notes on the diet composition of Anoles lizards, Anolis (Dactyloidae), in the Yasuni National Park (Ecuador)

Pinto, J.

10.1101/2023.06.15.545064 — ecology — Posted on 2023-06-15

2292 Transgene-Free Ex Utero Derivation of A Human Post-Implantation Embryo Model Solely from Genetically Unmodified Naive PSCs

Oldak, B.; Wildschutz, E.; Bondarenko, V.; Aguilera-Castrejon, A.; Zhao, C.; Tarazi, S.; Comar, M.-Y.; Ashouokhi, S.; Lokshtanov, D.; Roncato, F.; Viukov, S.; Ariel, E.; Rose, M.; Livnat, N.; Shani, T.; Joubran, C.; Cohen, R.; Addadi, Y.; Kedmi, M.; Keren-Shaul, H.; Petropoulos, S.; Lanner, F.; Novershtern, N.; Hanna, J. H.

10.1101/2023.06.14.544922 — developmental biology — Posted on 2023-06-15

2293 Crosstalk between glucose metabolism and morphogen signalling specifies tonotopic identity in developing hair cells.

O'Sullivan, J. D.; Blacker, T. S.; Scott, C. A.; Chang, W.; Ahmed, M.; Yianni, V.; Mann, Z. F.

10.1101/2022.04.11.487851 — developmental biology — Posted on 2023-06-15

2294 Identification of quiescent FOXC2+ spermatogonial stem cells in adult mammals

Wang, Z.; Jin, C.; Li, P.; Li, Y.; Tang, J.; Yu, Z.; Jiao, T.; Ou, J.; Wang, H.; Zou, D.; Li, M.; Mang, X.; Liu, J.; Lu, Y.; Li, K.; Zhang, N.; Yu, J.; Miao, S.; Wang, L.; Song, W.

10.1101/2022.12.20.521179 — developmental biology — Posted on 2023-06-15

2295 Retrieval of developmental social memories requires activation of the adult-born granule cell-CA2 circuit in mice

Laham, B. J.; Gore, I. R.; Brown, C. J.; Gould, E.

10.1101/2023.06.14.545015 — neuroscience — Posted on 2023-06-15

2296 Reconstructing visual illusory experiences from human brain activity

Cheng, F.; Horikawa, T.; Majima, K.; Tanaka, M.; Abdelhack, M.; Aoki, S. C.; Hirano, J.; Kamitani, Y.

10.1101/2023.06.15.545037 — neuroscience — Posted on 2023-06-15

2297 Did Moldehawera flowers evolve through mimicry with oil-producing Malpighiaceae?

de Queiroz, L. P.; Costa, J. A. S.; Costa, C. B. N.

10.1101/2023.06.15.545073 — plant biology — Posted on 2023-06-15

2298 A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

Hoolachan, J. M.; McCallion, E.; Sutton, E. R.; Cetin, O.; Pacheco-Torres, P.; Dimitriadi, M.; Okoh, M.; Walter, L. M.; Claus, P.; Wood, M. J.; Tonge, D. P.; Bowerman, M.

10.1101/2023.06.14.544899 — pathology — Posted on 2023-06-15

2299 Dual mechanical impact of β-escin on model lipid membranes

H. Moleiro, L.; Martin Romero, M. T.; Herraez, D.; Santiago, J. A.; Caselli, N.; Dargel, C.; Geisler, R.; Hellweg, T.; Monroy, F.

10.1101/2023.06.15.545043 — biophysics — Posted on 2023-06-15

2300 BGCFlow: Systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets

Nuhamunada, M.; Mohite, O. S.; Phaneuf, P. V.; Palsson, B.; Weber, T.

10.1101/2023.06.14.545018 — bioinformatics — Posted on 2023-06-15

2301 EphB3 receptor negatively regulates osteogenesis in mice

Rodriguez-Sosa, M. R.; Alfaro, D.; del Castillo, L. M.; Belarra, A.; Zapata, A. G.

10.1101/2023.06.15.544777 — cell biology — Posted on 2023-06-15

2302 Ground-state pluripotent stem cells are characterized by Rac1-dependent Cadherin-enriched F-actin protrusions

Liu, S.; Meng, Y.; Kanchanawong, P.

10.1101/2023.06.15.544897 — cell biology — Posted on 2023-06-15

2303 Functional Sexual Dimorphism in Human Nociceptors

Stratton, H. J.; Dolatyari, M.; Dumaire, N.; Moutal, A.; Ghetti, A.; Cotta, T.; Mitchell, S.; Yue, X.; Navratilova, E.; Porreca, F.

10.1101/2023.06.14.545010 — neuroscience — Posted on 2023-06-15

2304 Characterizing the power spectrum dynamics of the NREM to REM sleep transition

Serantes, D.; Cavelli, M.; Gonzalez, J.; Mondino, A.; Benedetto, L.; Torterolo, P.

10.1101/2023.06.14.544943 — neuroscience — Posted on 2023-06-15

2305 Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles

Gu, A. A.; Tran, P.; Prindle, A.; Kamat, N. P.; Steinkühler, J.

10.1101/2023.06.15.545042 — synthetic biology — Posted on 2023-06-15

2306 A Synthetic Protein Secretion System for Living Bacterial Therapeutics

Ahan, R. E.; Ozcelik, C. E.; Cagil, I. N.; Seker, U. O. S.

10.1101/2023.06.14.544856 — synthetic biology — Posted on 2023-06-15

2307 Configurable Full Subtractor and Adder by Lego-like Mixing and Matching of Engineered Bacteria

Bonnerjee, D.; Chakraborty, S.; Bagh, S.

10.1101/2023.06.15.545057 — synthetic biology — Posted on 2023-06-15

2308 Measuring C. elegans Ageing Through Non-Invasive Monitoring of Movement across Large Populations

Zavagno, G.; Raimundo, A.; Kirby, A.; Saunter, C.; Weinkove, D.

10.1101/2023.06.15.545090 — physiology — Posted on 2023-06-15

2309 Analysis of structure-activity and structure-mechanism relationships among thyroid stimulating hormone receptor binding chemicals by leveraging ToxCast library

Sahoo, A. K.; Baskaran, S. P.; Chivukula, N.; Kumar, K.; Samal, A.

10.1101/2023.06.14.544937 — pharmacology and toxicology — Posted on 2023-06-15

2310 Cryo2Struct: A Large Labeled Cryo-EM Density MapDataset for AI-based Reconstruction of ProteinStructures

Giri, N.; Cheng, J.

10.1101/2023.06.14.545024 — bioinformatics — Posted on 2023-06-15

2311 Deconvolution reveals compositional differences in high-grade serous ovarian cancer subtypes

Hippen, A. A.; Davidson, N. R.; Barnard, M. E.; Weber, L. M.; Gertz, J.; Doherty, J. A.; Hicks, S. C.; Greene, C. S.

10.1101/2023.06.14.544991 — bioinformatics — Posted on 2023-06-15

2312 CFSA: Comparative Flux Sampling Analysis as a guide for strain design

van Rosmalen, R. P.; Moreno-Paz, S.; Duman-Ozdamar, E. Z.; Suarez-Diez, M.

10.1101/2023.06.15.545085 — bioengineering — Posted on 2023-06-15

2313 Incorporating strontium enriched amorphous calcium phosphate granules in collagen/collagen-magnesium-hydroxyapatite osteochondral scaffold improves subchondral bone repair

Xu, J.; Vecstaudza, J.; Wesdorp, M. A.; Labberte, M.; Kops, N.; Salerno, M.; Kok, J.; Simon, M.; Harmand, M.-F.; Vancikova, K.; van Rietbergen, B.; Misciagna, M. M.; Dolcini, L.; Filardo, G.; Farrell, E.; van Osch, G. J. V. M.; Locs, J.; Brama, P. A. J.

10.1101/2023.06.15.545062 — bioengineering — Posted on 2023-06-15

2314 Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies

Orris, B.; Sung, M. W.; Bhat, S.; Xu, Y.; Huynh, K. W.; Han, S.; Johnson, D. C.; Bosbach, B.; Shields, D. J.; Stivers, J. T.

10.1101/2023.06.15.544806 — biochemistry — Posted on 2023-06-15

2315 Myosin 10 uses its MyTH4 and FERM domains differentially to support two aspects of spindle pole biology required for mitotic spindle bipolarity

Yim, Y.-I.; Pedrosa, A.; Wu, X.; Chinthalapudi, K.; Cheney, R. E.; Hammer, J.

10.1101/2023.06.15.545002 — cell biology — Posted on 2023-06-15

2316 Beclin1 is essential for intestinal homeostasis.

Tran, S.; Juliani, J.; Harris, T. J.; Evangelista, M.; Ratcliffe, J.; Ellis, S. L.; Baloyan, D.; Reehorst, C. M.; Nightingale, R.; Luk, I. Y.; Jenkins, L. J.; Ghilas, S.; Yakou, M. H.; Inguanti, C.; Johnson, C.; Buchert, M.; Lee, J. C.; De Cruz, P.; Duszyc, K.; Gleeson, P. A.; Kile, B. T.; Mielke, L. A.; Yap, A. S.; Mariadason, J.; Fairlie, W. D.; Lee, E. F.

10.1101/2023.06.14.545007 — cell biology — Posted on 2023-06-15

2317 The role of Kölliker-Fuse nucleus in breathing variability

John, S.; Barnett, W.; Abdala, A. P.; Zoccal, D. B.; Rubin, J.; Molkov, Y.

10.1101/2023.06.15.545086 — neuroscience — Posted on 2023-06-15

2318 Neuromechanical Justification of Lower-Limb Functional Tests for a Return to Running: A Muscle Coordination Analysis

Saito, H.; Yamano, A.; Suzuki, N.; Matsushita, K.; Yokoyama, H.; Sasaki, A.; Takahashi, T.; Nakazawa, K.

10.1101/2023.06.15.545091 — neuroscience — Posted on 2023-06-15

2319 IKK1 kinase coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy

Espinosa, L.; Pecharroman Ruiz, I.; Sole, L.; Alvarez-Villanueva, D.; Lobo, T.; Alonso, J.; Bertran, j.; Sabido, E.; Borras, E.; Garcia-Hernandez, V.; garrido, M.; Seoane, J.; Bigas, A.; Villanueva, A.; Martinez-Iniesta, M.; Bonfill, E.; Iurlaro, R.; Santos, C.; Guillen, Y.; Montoto, A.; Gimenez, G.; Iglesias, M.; salazar, R.

10.1101/2023.06.13.544711 — cancer biology — Posted on 2023-06-15

2320 Glycochenodeoxycholic acid and ceramide suppress the antiviral effect of 25-hydroxycholesterol against human norovirus infection in human intestinal enteroids

Vinje, J.; Mboko, W.; Chhabra, P.; Montmayeur, A.; Xu, R.; Costantini, V. P.

10.1101/2023.06.12.544665 — genetics — Posted on 2023-06-15

2321 Conservation networks do not match the ecological requirements of amphibians

Matutini, F.; Baudry, J.; Fortin, M.-J.; Pain, G.; Pithon, J.

10.1101/2022.07.18.500425 — ecology — Posted on 2023-06-15

2322 Unraveling the dynamic transcriptomic changes during the dimorphic transition of Talaromyces marneffei through time-course analysis

Du, M.; Tao, C.; Hu, X.; Zhang, Y.; Kan, J.; Wang, J.; Yang, E.

10.1101/2023.06.12.544618 — microbiology — Posted on 2023-06-15

2323 Neural Signatures of Emotion Regulation

Rieck, J.; Wrobel, J.; Porras, A. R.; McRae, K.; Gowin, J.

10.1101/2023.06.12.544668 — neuroscience — Posted on 2023-06-15

2324 CRISPR-based gene drives generate super-Mendelian inheritance in the disease vector Culex quinquefasciatus.

Harvey-Samuel, T.; Feng, X.; Okamoto, E. M.; Purusothaman, D.-K.; Leftwich, P. T.; Alphey, L.; Gantz, V. M.

10.1101/2023.06.12.544656 — synthetic biology — Posted on 2023-06-15

2325 Defining the single base importance of human mRNAs and lncRNAs

Fan, R.; Ji, X.; Li, J.; Cui, Q.; Cui, C.

10.1101/2023.06.12.544536 — bioinformatics — Posted on 2023-06-15

2326 ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer.

Pandey, A.; Cousin, H.; Horr, B.; Alfandari, D.

10.1101/2023.06.13.544797 — developmental biology — Posted on 2023-06-15

2327 Processing and Storage Methods Affect Oral and Gut Microbiome Composition

Superdock, D. K.; Zhang, W.; Poole, A. C.

10.1101/2023.06.13.544865 — microbiology — Posted on 2023-06-14

2328 Emergence of community behaviors in the gut microbiota upon drug treatment

Garcia-Santamarina, S.; Kuhn, M.; Devendran, S.; Maier, L.; Driessen, M.; Mateus, A.; Mastrorilli, E.; Brochado, A. R.; Savitski, M. M.; Patil, K. R.; Zimmermann, M.; Bork, P.; Typas, A.

10.1101/2023.06.13.544832 — microbiology — Posted on 2023-06-14

2329 Rapid and Signal Crowdedness-Robust In-Situ Sequencing through Hybrid Block Coding

Chang, T.; Han, W.; Jiang, M.; Li, J.; Liao, Z.; Shen, J.; Chen, Z.; Fei, P.; Ren, X.; Pang, Y.; Wang, G.; Wang, J.; Huang, Y.

10.1101/2022.11.16.516714 — genomics — Posted on 2023-06-15

2330 Interaction of genital microbiota in infertile couples

Baud, D.; Peric, A.; Vidal, A.; Weiss, J.; Engel, P.; Das, S.; Stojanov, M.

10.1101/2023.06.14.544778 — microbiology — Posted on 2023-06-14

2331 Host ZCCHC3 blocks HIV-1 infection and production by a dual mechanism

Yi, B.; Tanaka, Y. L.; Kosako, H.; Butlertanaka, E. P.; Sengupta, P.; Lippincott-Schwartz, J.; Yoshimura, S. H.; Saito, A.

10.1101/2023.06.14.544911 — microbiology — Posted on 2023-06-14

2332 Revealing and reshaping attractor dynamics in large networks of cortical neurons

Beer, C.; Barak, O.

10.1101/2023.05.08.539868 — neuroscience — Posted on 2023-06-15

2333 Deep Learning Glioma Grading with the Tumor Microenvironment Analysis Protocol for A Comprehensive Learning, Discovering, and Quantifying Microenvironmental Features

Pytlarz, M.; Wojnicki, K.; Pilanc, P.; Kaminska, B.; Crimi, A.

10.1101/2023.06.13.544739 — bioinformatics — Posted on 2023-06-15

2334 Silk Road Revealed: Mechanism of silk fibre formation in Bombyx mori

Moreno-Tortolero, R. O.; Luo, Y.; Parmeggiani, F.; Skaer, N.; Walker, R.; Serpell, L. O.; Holland, C.; Davis, S. A.

10.1101/2023.06.02.543394 — biochemistry — Posted on 2023-06-15

2335 Serological evidence of high pathogenicity virus infection in Eidolon helvum fruit bats in Nigeria

Cantoni, D.; Mayora Neto, M.; Auld, B.; Da Costa, K.; Del Rosario, J.; Ameh, V. O.; Sabeta, C. T.; Derveni, M.; Hamlet, A.; Wright, E.; Scott, S.; Giotis, E. S.; Banyard, A.; Temperton, N. J.

10.1101/2023.06.14.544916 — microbiology — Posted on 2023-06-14

2336 Host ZCCHC3 blocks HIV-1 infection and production by a dual mechanism

Yi, B.; Tanaka, Y. L.; Kosako, H.; Butlertanaka, E. P.; Sengupta, P.; Lippincott-Schwartz, J.; Saito, A.; Yoshimura, S. H.

10.1101/2023.06.14.544911 — microbiology — Posted on 2023-06-14

2337 LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation

10.1101/2023.06.14.545012 — immunology — Posted on 2023-06-15

2338 A Functional Data Analysis Approach to RuBisCO Engineering

McCormack, A. C.

10.1101/2023.06.14.544690 — synthetic biology — Posted on 2023-06-15

2339 Effects of lactate, super-GDF9 and low oxygen tension during biphasic in vitro maturation on the bioenergetic profiles of mouse cumulus-oocyte-complex

Akin, N.; Ates, G.; von Mengden, L.; Herta, A.-C.; Meriggioli, C.; Billooye, K.; Stocker, W. A.; Ghesquiere, B.; Harrison, C. A.; Cools, W.; Klamt, F.; Massie, A.; Smitz, J.; Anckaert, E.

10.1101/2022.11.09.514870 — developmental biology — Posted on 2023-06-15

2340 A miRNA screen identifies a transcriptional program controlling adult stem cell maintenance in organoids

Robert, J.; Vlachavas, E.-I.; Lemaitre, G.; Chatziioannou, A.; Puceat, M.; Delom, F.; Fessart, D.

10.1101/314658 — cell biology — Posted on 2023-06-15

2341 Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells

Beale, A. D.; Hayter, E. A.; Crosby, P.; Valekunja, U. K.; Edgar, R. S.; Chesham, J. E.; Maywood, E. S.; Labeed, F. H.; Reddy, A. B.; Wright, K. P.; Lilley, K. S.; Bechtold, D.; Hastings, M. H.; O'Neill, J. S.

10.1101/2021.10.11.463714 — cell biology — Posted on 2023-06-15

2342 A KDELR-mediated ER retrieval system guides the signaling pathways of UPR and AMPK to maintain cellular homeostasis

Zhu, M.; Fang, Z.; Wu, Y.; Dong, F.; Wang, Y.; Zheng, F.; Ma, X.; Ma, S.; He, J.; Hill, D. L.; Liu, X.; Yao, X.; Fu, C.

10.1101/2023.06.14.545011 — cell biology — Posted on 2023-06-15

2343 A trade-off between proliferation and defense in the fungal pathogen Cryptococcus at alkaline pH is controlled by the transcription factor GAT201

Hughes, E. S.; He, Z.; Ballou, E. R.; Wallace, E.

10.1101/2023.06.14.543486 — microbiology — Posted on 2023-06-14

2344 Aerobic denitrification as N2O source in microbial communities

Roothans, N.; Gabriels, M.; Pabst, M.; van Loosdrecht, M. C. M.; Laureni, M.

10.1101/2023.06.14.544945 — microbiology — Posted on 2023-06-14

2345 Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories

Wuestefeld, A.; Baumeister, H.; Adams, J. N.; de Flores, R.; Hodgetts, C.; Mazloum-Farzaghi, N.; Olsen, R. K.; Puliyadi, V.; Tran, T. T.; Bakker, A.; Canada, K. L.; Dalton, M. A.; Daugherty, A. M.; La Joie, R.; Wang, L.; Bedard, M.; Buendia, E.; Denning, A.; del Mar Arroyo-Jimenez, M.; Artacho-Perula, E.; Irwin, D. J.; Ittyerah, R.; Lee, E. B.; Lim, S.; del Pilar Marcos-Rabal, M.; Iniguez de Onzono Martin, M. M.; Munoz Lopez, M.; de la Rosa Prieto, C.; Schuck, T.; Trotman, W.; Vela, A.; Yushkevich, P.; Amunts, K.; Augustinack, J. C.; Ding, S.-L.; Insausti, R.; Kedo, O.; Berron, D.; Wisse, L. E

10.1101/2023.05.24.542054 — neuroscience — Posted on 2023-06-15

2346 Human voltage-gated Na+ and K+ channel properties underlie sustained fast AP signaling

Wilbers, R.; Metodieva, V. D.; Duverdin, S.; Heyer, D. B.; Galakhova, A. A.; Mertens, E. J.; Versluis, T. D.; Baayen, J. C.; Idema, S.; Noske, D. P.; Verburg, N.; Willemse, R. B.; de Witt Hamer, P. C.; Kole, M. H. P.; de Kock, C. P. J.; Mansvelder, H. D.; Goriounova, N. A.

10.1101/2022.11.29.518317 — neuroscience — Posted on 2023-06-15

2347 Structural and functional specializations of human fast spiking neurons support fast cortical signaling

Wilbers, R.; Galakhova, A. A.; Driessens, S. L.; Heistek, T. S.; Metodieva, V. D.; Hagemann, J.; Heyer, D. B.; Mertens, E. J.; Deng, S.; Idema, S.; de Witt Hamer, P. C.; Noske, D. P.; van Schie, P.; Kommers, I.; Luan, G.; Li, T.; Shu, Y.; de Kock, C. P. J.; Mansvelder, H. D.; Goriounova, N. A.

10.1101/2022.11.29.518193 — neuroscience — Posted on 2023-06-15

2348 Theoretical assessment of persistence and adaptation in weeds with complex life cycles

Lauenroth, D.; Gokhale, C.

10.1101/2022.08.12.503772 — plant biology — Posted on 2023-06-15

2349 Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia

Chen, C.; Qin, Y.; Xu, Y.; Wang, X.; Lei, W.; Shen, X.; Chen, L.; Wang, L.; Gong, J.; Wang, Y.; Hu, S.; Liu, D.

10.1101/2023.01.23.525218 — cell biology — Posted on 2023-06-15

2350 Partially hydrolyzed guar gum attenuates the symptoms of SARS-CoV-2 infection through gut microbiota modulation in an animal model.

Yang, J.; Song, I.; Saito, M.; Hartanto, T.; Ichinohe, T.; Fukuda, S.

10.1101/2023.06.13.544519 — microbiology — Posted on 2023-06-14

2351 Phage predation and antibiotic exposure are inversely associated with disease severity and shape pathogen genetic diversity in cholera patients

Madi, N.; Cato, E. T.; Sayeed, M. A.; Islam, K.; Khabir, M. I. U.; Bhuiyan, M. T. R.; Begum, Y.; Rashid, M. M.; Creasy-Marrazzo, A.; Brinkley, L.; Kamat, M.; Cuenod, A.; Bailey, L. S.; Basso, K. B.; Qadri, F.; Khan, A. I.; Shapiro, B. J.; Nelson, E. J.

10.1101/2023.06.14.544933 — microbiology — Posted on 2023-06-14

2352 The parasitic lifestyle of an archaeal symbiont

Hamm, J. N.; Liao, Y.; von Kügelgen, A.; Dombrowski, N.; Landers, E.; Brownlee, C.; Johansson, E. M. V.; Whan, R. M.; Baker, M. A. B.; Baum, B.; Bharat, T. A. M.; Duggin, I. G.; Spang, A.; Cavicchioli, R.

10.1101/2023.02.24.529834 — microbiology — Posted on 2023-06-14

2353 Comparison of genomic diversity between single and pooled Staphylococcus aureus colonies isolated from human colonisation cultures.

Raghuram, V.; Gunoskey, J. J.; Hofstetter, K. S.; Jacko, N. F.; Shumaker, M. J.; Hu, Y.; Read, T.; David, M. Z.

10.1101/2023.06.14.544959 — microbiology — Posted on 2023-06-14

2354 Differential contribution of nitrifying prokaryotes to groundwater nitrification

Krueger, M.; Chaudhari, N.; Thamdrup, B.; Overholt, W.; Bristow, L.; Taubert, M.; Kuesel, K.; Jehmlich, N.; Von Bergen, M.; Herrmann, M.

10.1101/2023.03.10.532121 — microbiology — Posted on 2023-06-14

2355 Striatal integration of inverse dopamine and serotonin signals gates learning

Pinto, D. F. C.; Pomrenze, M. B.; Guo, M. Y.; Bentzley, B. S.; Eshel, N.; Malenka, R. C.

10.1101/2023.06.14.544997 — neuroscience — Posted on 2023-06-14

2356 The tRNA Gm18 Methyltransferase TARBP1 Promotes Hepatocellular Carcinoma Progression via Metabolic Reprogramming of Glutamine

Shi, X.; Zhang, Y.; Wang, Y.; Wang, J.; Gao, Y.; Wang, R.; Wang, L.; Xiong, M.; Ou, N.; Liu, Q.; Ma, H.; Cai, J.; Chen, H.

10.1101/2023.06.14.544902 — cancer biology — Posted on 2023-06-14

2357 Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders

Hiramoto, T.; Sumiyoshi, A.; Kato, R.; Yamauchi, T.; Kang, G.; Matsumura, B.; Stevens, L. J.; Ryoke, R.; Nonaka, H.; Machida, A.; Nomoto, K.; Mogi, K.; Kikusui, T.; Kawashima, R.; Hiroi, N.

10.1101/2023.06.14.545013 — neuroscience — Posted on 2023-06-14

2358 Spatially clustered neurons encode vocalization categories in the bat midbrain

Lawlor, J.; Wohlgemuth, M.; Moss, C. F.; Kuchibhotla, K. V.

10.1101/2023.06.14.545029 — neuroscience — Posted on 2023-06-14

2359 Caffeinated soda intake in children is associated with neurobehavioral risk factors for substance misuse

Kwon, M.; Kim, H.; Yang, J.; Lee, Y.; Hur, J. K.; Lee, T.-H.; Bjork, J. M.; Ahn, W.-Y.

10.1101/2021.02.17.431718 — neuroscience — Posted on 2023-06-15

2360 Mechanically stimulated osteocytes maintain tumor dormancy in bone metastasis of non-small cell lung cancer by releasing small extracellular vesicles

Xie, J.; Xu, Y.; Liu, X.; Long, L.; Chen, J.; Shao, Y.; Cai, Z.; Zhang, Z.; Zhou, R.; Leng, J.; Bai, X.; Song, Q.

10.1101/2023.06.14.544869 — cancer biology — Posted on 2023-06-14

2361 Discovery of Competent Chromatin Regions in Human Embryonic Stem Cells

Pulecio, J.; Tayyebi, Z.; Liu, D.; Wong, W.; Luo, R.; Damodaran, J. R.; Kaplan, S.; Cho, H.; Yan, J.; Murphy, D. J.; Rickert, R.; Shukla, A.; Zhong, A.; Gonzalez, F.; Yang, D.; Li, W.; Zhou, T.; Apostolou, E.; Leslie, C.; Huangfu, D.

10.1101/2023.06.14.544990 — developmental biology — Posted on 2023-06-14

2362 Identification of Candidate Mitochondrial Inheritance Determinants Using the Mammalian Cell-Free System

Zuidema, D.; Jones, A.; Song, W.-H.; Zigo, M.; Sutovsky, P.

10.1101/2023.01.23.525177 — cell biology — Posted on 2023-06-14

2363 Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level

Yamaguchi, A.; Maeshige, N.; Noguchi, H.; Yan, J.; Ma, X.; Uemura, M.; Kondo, H.; Sarosiek, K.; Fujino, H.

10.1101/2023.06.14.544906 — immunology — Posted on 2023-06-14

2364 Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1β

Zigdon, M.; Sawaed, J.; Zelik, L.; Binyamin, D.; Ben-Simon, S.; Asulin, N.; Levin, R.; Modilevsky, S.; Naama, M.; Telpaz, S.; Rubin, E.; Awad, A.; Sawaed, W.; Harshuk-Shabso, S.; Nuriel-Ohayon, M.; Werbner, M.; Winter, S. E.; Apte, R. N.; Voronov, E.; Bel, S.

10.1101/2023.06.14.544934 — immunology — Posted on 2023-06-14

2365 Alterations in the Mammary Gland and Tumor Microenvironment of Formerly Obese Mice

Kuziel, G.; Moore, B. N.; Haugstad, G. P.; Xiong, Y.; Williams, A. E.; Arendt, L. M.

10.1101/2023.06.14.545000 — cancer biology — Posted on 2023-06-14

2366 SMCHD1 loss triggers DUX4 expression by disrupting splicing in FSHD2

Engal, E.; Sharma, A.; Taqatqa, N.; Bentata, M.; Jaffe-Herman, S.; Geminder, O.; Lewis, R.; Gotkine, M.; Salton, M.; Drier, Y.

10.1101/2023.02.27.530258 — genomics — Posted on 2023-06-14

2367 Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy

McFaline-Figueroa, J. L.; Srivatsan, S.; Hill, A. J.; Gasperini, M.; Jackson, D. L.; Saunders, L.; Domcke, S.; Regalado, S. G.; Lazarchuck, P.; Alvarez, S.; Monnat, R. J.; Shendure, J.; Trapnell, C.

10.1101/2023.03.10.531983 — genomics — Posted on 2023-06-14

2368 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

Kuzmin, E.; Baker, T.; Lesluyes, T.; Monlong, J.; Abe, K. T.; Coelho, P. P.; Schwartz, M.; Zou, D.; Morin, G.; Pacis, A.; Yang, Y.; Martinez, C.; Barber, J.; Kuasne, H.; Li, R.; Bourgey, M.; Fortier, A.-M.; Davison, P. G.; Omeroglu, A.; Guiot, M. C.; Morris, Q.; Kleinman, C. L.; Huang, S.; Gingras, A.-C.; Ragoussis, I.; Bourque, G.; van Loo, P.; Park, M.

10.1101/2023.06.10.544434 — genomics — Posted on 2023-06-14

2369 Positive association between alleles at selectively neutral loci

Potapova, N. A.; Kondrashov, A. S.

10.1101/2023.06.14.544962 — genetics — Posted on 2023-06-14

2370 Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and systemically regulates longevity from serotonergic and GABAergic neurons

Lazaro-Pena, M.; Cornwell, A. B.; Diaz-Balzac, C. A.; Das, R.; Ward, Z. C.; Macoretta, N.; Thakar, J.; Samuelson, A.

10.1101/2023.01.11.523661 — genetics — Posted on 2023-06-14

2371 Nonviral base editing of KCNJ13 mutation preserves vision in an inherited retinal channelopathy

Kabra, M.; Shahi, P. K.; Wang, Y.; Sinha, D.; Spillane, A.; Newby, G. A.; Saxsena, S.; Tong, Y.; Chang, Y.; Abdeen, A. A.; Edwards, K.; Thiesen, C.; Gamm, D.; Liu, D. R.; Gong, S. S.; Saha, K.; Pattnaik, B. R.

10.1101/2022.07.12.499808 — genetics — Posted on 2023-06-14

2372 Single Cell Transcriptomics-informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage

Papalamprou, A.; Yu, V.; Jiang, W.; Sheyn, J.; Stefanovic, T.; Chen, A.; Castaneda, C.; Chavez, M.; Sheyn, D.

10.1101/2023.04.10.536240 — developmental biology — Posted on 2023-06-14

2373 Fluorochrome-dependent specific changes in spectral profiles using different compensation beads or human cells in full spectrum cytometry

Shevchenko, Y.; Lurje, I.; Tacke, F.; Hammerich, L.

10.1101/2023.06.14.544540 — immunology — Posted on 2023-06-14

2374 Interactions between Mycoplasma mycoides subsp. mycoides and bovine macrophages under physiological conditions

Totte, P.; Bonnefois, T.; Manso-Silvan, L.

10.1101/2022.12.06.519279 — immunology — Posted on 2023-06-14

2375 Hyperglycosylation of prosaposin in tumor DCs promotes immune escape in cancer

Sharma, P.; Zhang, X.; Ly, K.; Kim, J. H.; Wan, Q.; Kim, J.; Lou, M.; Kain, L.; Teyton, L.; Winau, F.

10.1101/2023.06.14.545005 — immunology — Posted on 2023-06-14

2376 Combination of Polymeric Micelle Formulation of TGFβ Receptor Inhibitors and Paclitaxel Produce Consistent Response Across Different Mouse Models of TNBC

Vinod, N.; Hwang, D.; Fussell, S. C.; Owens, T. C.; Tofade, O. C.; Copling, S.; Ramsey, J. D.; Radler, P. D.; Atkins, H. M.; Livingston, E. E.; Ezzel, J. A.; Sokolsky, M.; Yuan, H.; perou, c.; Kabanov, A.

10.1101/2023.06.14.544381 — cancer biology — Posted on 2023-06-14

2377 AutoRNC: an automated modeling program for building atomic models of ribosome-nascent chain complexes

McDonnell, R. T.; Elcock, A. H.

10.1101/2023.06.14.544999 — biophysics — Posted on 2023-06-14

2378 Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain

Nawarathnage, S.; Tseng, Y.-J.; Soleimani, S.; Smith, T.; Pedroza-Romo, M. J.; Abiodun, W. O.; Egbert, C.; Madhysanka, D.; Bunn, D.; Wood, B.; Tsubaki, E.; Stewart, C.; Brown, S.; Doukov, T.; Andersen, J.; Moody, J. D.

10.1101/2023.06.14.544429 — biochemistry — Posted on 2023-06-14

2379 Symbiotic nutrient exchange enhances the long-term survival of cassiosomes, the autonomous stinging-cell structures of Cassiopea

Toullec, G.; Lyndby, N. H.; Banc Prandi, G.; Pogoreutz, C.; Martin Olmos, C.; Meibom, A.; Radecker, N.

10.1101/2023.06.14.544940 — ecology — Posted on 2023-06-14

2380 Field margins as substitute habitat for the conservation of birds in agricultural wetlands

Mallet, P.; Bechet, A.; Sirami, C.; Mesleard, F.; Blanchon, T.; Calatayud, F.; Dagonet, T.; Gaget, E.; Leray, C.; Galewski, T.

10.1101/2022.05.05.490780 — ecology — Posted on 2023-06-14

2381 COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in C. elegans germline stem cells

Osterli, E.; Ellenbecker, M.; Wang, X.; Terzo, M.; Jacobson, K.; Cuello, D.; Voronina, E.

10.1101/2022.06.22.497213 — developmental biology — Posted on 2023-06-14

2382 Zebrahub - Multimodal Zebrafish Developmental Atlas Reveals the State Transition Dynamics of Late Vertebrate Pluripotent Axial Progenitors

Lange, M.; Granados, A.; VijayKumar, S.; Bragantini, J.; Ancheta, S.; Santhosh, S.; Borja, M.; Kobayashi, H.; McGeever, E.; Solak, A. C.; Yang, B.; Zhao, X.; Liu, Y.; Detweiler, A. M.; Paul, S.; Mekonen, H.; Lao, T.; Banks, R.; Kim, Y.-J.; Jacobo, A.; Balla, K.; Awayan, K.; D'souza, S.; Haase, R.; Dizeux, A.; Pourquie, O.; Gomez-Sjoberg, R.; Huber, G.; Serra, M.; Neff, N.; Pisco, A.; Royer, L. A.

10.1101/2023.03.06.531398 — developmental biology — Posted on 2023-06-14

2383 Wg/Wnt-signaling induced nuclear translocation of β-catenin is attenuated by a β-catenin peptide through its interaction with IFT-A in development and cancer cells

Vuong, L. T.; Mlodzik, M.

10.1101/2023.06.14.544986 — cell biology — Posted on 2023-06-14

2384 High-resolution mapping of cell-cycle dynamics during steady-state T-cell development and regeneration in vivo

Kunze-Schumacher, H.; Verheyden, N. A.; Grewers, Z.; Meyer-Hermann, M.; Greiff, V.; Robert, P. A.; Krueger, A.

10.1101/2023.06.14.544919 — immunology — Posted on 2023-06-14

2385 Predicting T cell activation based on intracellular calcium fluctuations

This, S.; Costantino, S.; Melichar, H. J.

10.1101/2023.06.14.545014 — immunology — Posted on 2023-06-14

2386 A sparse code for natural sound context in auditory cortex

Lopez Espejo, M.; David, S. V.

10.1101/2023.06.14.544866 — neuroscience — Posted on 2023-06-14

2387 Modeling the Effects of Transcranial Magnetic Stimulation on Spatial Attention

Jing, Y.; Numssen, O.; Weise, K.; Kalloch, B.; Buchberger, L.; Haueisen, J.; Hartwigsen, G.; Knoesche, T.

10.1101/2023.01.11.523548 — neuroscience — Posted on 2023-06-14

2388 Many but not all deep neural network audio models capture brain responses and exhibit correspondence between model stages and brain regions

Tuckute, G.; Feather, J.; Boebinger, D.; McDermott, J. H.

10.1101/2022.09.06.506680 — neuroscience — Posted on 2023-06-14

2389 A Functional Data Analysis Approach to RuBisCO Engineering

McCormack, A. C.

10.1101/2023.06.14.544690 — synthetic biology — Posted on 2023-06-14

2390 Single-cell transcriptomic analysis of pea shoot development and cell-type-specific responses to boron deficiency

Chen, X.; Ru, Y.; Takahashi, H.; Nakazono, M.; Shabala, S.; Smith, S. M.; Yu, M.

10.1101/2023.06.14.545017 — plant biology — Posted on 2023-06-14

2391 Characterization of cotton virus A, a novel and distinct member of the genus Caulimovirus with endogenous viral elements in Gossypium spp.

West-Ortiz, M.; Stuehler, D.; Pollock, E.; Wilson, J.; Preising, S.; Alabi, O.; Fuchs, M.; Heck, M.; Olmedo-Velarde, A.

10.1101/2023.06.14.544975 — plant biology — Posted on 2023-06-14

2392 Subgenome dominance shapes novel gene evolution in the decaploid pitcher plant Nepenthes gracilis

Saul, F.; Scharmann, M.; Wakatake, T.; Rajaraman, S.; Marques, A.; Freund, M.; Bringmann, G.; Channon, L.; Becker, D.; Carroll, E.; Low, Y. W.; Lindqvist, C.; Gilbert, K. J.; Renner, T.; Masuda, S.; Richter, M.; Vogg, G.; Shirasu, K.; Michael, T. P.; Hedrich, R.; Albert, V. A.; Fukushima, K.

10.1101/2023.06.14.544965 — plant biology — Posted on 2023-06-14

2393 Single-cell RNA sequencing identifies response of renal lymphatic endothelial cells to acute kidney injury

Creed, H. A.; Kannan, S.; Tate, B. L.; Banerjee, P.; Mitchell, B. M.; Chakraborty, S.; Rutkowski, J. M.

10.1101/2023.06.09.544380 — pathology — Posted on 2023-06-14

2394 Biophysical evolution of the receptor binding domains of SARS-CoVs

Upadhyay, V.; Panja, S.; Lucas, A.; Patrick, C.; Mallela, K.

10.1101/2023.06.13.544630 — biophysics — Posted on 2023-06-14

2395 Structure Reveals Homology in Elevator Transporters

Trebesch, N.; Tajkhorshid, E.

10.1101/2023.06.14.544989 — biophysics — Posted on 2023-06-14

2396 emObject: domain specific data abstraction for spatial omics

Baker, E. A. G.; Huang, M.-Y.; Lam, A.; Rahim, M. K.; Bieniosek, M. F.; Wang, B.; Zhang, N. R.; Mayer, A. T.; Trevino, A. E.

10.1101/2023.06.07.543950 — bioinformatics — Posted on 2023-06-14

2397 Single-tier point-of-care serodiagnosis of Lyme disease

Ghosh, R.; Joung, H.-A.; Goncharov, A.; Palanisamy, B.; Ngo, K.; Pejcinovic, K.; Krockenberger, N.; Horn, E. J.; Garner, O. B.; Ghazal, E.; O' Kula, A.; Arnaboldi, P. M.; Dattwyler, R. J.; Ozcan, A.; Di Carlo, D.

10.1101/2023.06.14.544508 — bioengineering — Posted on 2023-06-14

2398 Protein design using structure-based residue preferences

Ding, D.; Shaw, A. Y.; Sinai, S.; Rollins, N. J.; Prywes, N.; Savage, D.; Laub, M. T.; Marks, D. S.

10.1101/2022.10.31.514613 — bioengineering — Posted on 2023-06-14

2399 Generative artificial intelligence GPT-4 accelerates knowledge mining and machine learning for synthetic biology

Xiao, Z.; Li, W.; Moon, H.; Roell, G. W.; Chen, Y.; Tang, Y. J.

10.1101/2023.06.14.544984 — bioengineering — Posted on 2023-06-14

2400 Structural modeling of cytokine-receptor-JAK2 signaling complexes using AlphaFold Multimer

Pogozheva, I. D.; Cherepanov, S.; Park, S.-J.; Raghavan, M.; Im, W.; Lomize, A.

10.1101/2023.06.14.544971 — biochemistry — Posted on 2023-06-14

2401 Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits

Grove, D. J.; Levine, D. J.; Kearse, M. G.

10.1101/2022.11.18.517125 — biochemistry — Posted on 2023-06-14

2402 Evolutionary engineering a larger porin using a loop-to-hairpin mechanism

Dhar, R.; Bowman, A. M.; Hatungimana, B.; Slusky, J. S. G.

10.1101/2023.06.14.544993 — biochemistry — Posted on 2023-06-14

2403 A nuclear signal in prophase determines centrosome positioning and ensures efficient mitotic spindle assembly

Ferreira, J. G.; Lima, J. T.

10.1101/2023.06.14.544905 — cell biology — Posted on 2023-06-14

2404 Mechanisms of cilia regeneration in Xenopus multiciliated epithelium in vivo.

Rao, V. G.; Subramanianbalachandar, V.; Magaj, M. M.; Redemann, S.; Kulkarni, S. S.

10.1101/2023.06.14.544972 — cell biology — Posted on 2023-06-14

2405 Cas phosphorylation regulates focal adhesion assembly

Kumar, S.; Stainer, A.; Dubrulle, J.; Simpkins, C.; Cooper, J.

10.1101/2022.12.19.521109 — cell biology — Posted on 2023-06-14

2406 Not everything, not everywhere, not all at once: a study of brain-wide encoding of movement

Wang, Z. A.; Chen, S.; Liu, Y.; Liu, D.; Svoboda, K.; Li, N.; Druckmann, S.

10.1101/2023.06.08.544257 — neuroscience — Posted on 2023-06-14

2407 Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling

Mäki-Marttunen, T.; Blackwell, K. T.; Akkouh, I.; Shadrin, A.; Valstad, M.; Elvsashagen, T.; Linne, M.-L.; Djurovic, S.; Einevoll, G. T.; Andreassen, O.

10.1101/2023.06.14.544920 — neuroscience — Posted on 2023-06-14

2408 AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Trepte, P.; Secker, C.; Kostova, S.; Maseko, S. B.; Choi, S. G.; Blavier, J.; Minia, I.; Silva Ramos, E.; Cassonnet, P.; Golusik, S.; Zenkner, M.; Beetz, S.; Liebich, M. J.; Scharek, N.; Schuetz, A.; Sperling, M.; Lisurek, M.; Wang, Y.; Spirohn, K.; Hao, T.; Calderwood, M. A.; Hill, D. E.; Landthaler, M.; Olivet, J.; Twizere, J.-C.; Vidal, M.; Wanker, E. E.

10.1101/2023.06.14.544560 — systems biology — Posted on 2023-06-14

2409 HSP90 inhibitor gedunin impairs glioblastoma proliferation and invasiveness

Costa, T. E. M. M.; Padua, T. A.; Pereira, J. X.; Rodrigues, V. G.; Seito, L. N.; Cunha, E. M.; Filgueiras, C. C.; Abreu-Villaca, Y.; Manhaes, A. C.; Maya-Monteiro, C. M.; Henriques, M. d. G.; Krahe, T. E.; Penido, C.

10.1101/2023.06.02.543101 — pharmacology and toxicology — Posted on 2023-06-14

2410 Evidence of Disrupted-in Schizophrenia 1 (DISC1) as an arsenic binding protein and implications regarding its role as a translational activator

Watanabe, M.; Khu, T. M.; Warren, G.; Shin, J.; Stewart, C. E.; Roche, J.

10.1101/2023.06.14.544995 — biophysics — Posted on 2023-06-14

2411 Alternative splicing is coupled to gene expression in a subset of variably expressed genes

Karlebach, G.; Steinhaus, R.; Danis, D.; Devoucoux, M.; Anczukow, O.; Sheynkman, G.; Seelow, D.; Robinson, P. N.

10.1101/2023.06.13.544742 — genomics — Posted on 2023-06-14

2412 Cyclophosphamide induces the loss of taste bud innervation in mice.

Wood, R. M.; Vasquez, E. L.; Gutierrez Kuri, E.; Connelly, K.; Humayun, S.; Macpherson, L. J.

10.1101/2023.06.14.544942 — neuroscience — Posted on 2023-06-14

2413 Avoiding false discoveries: Revisiting an Alzheimer's disease snRNA-Seq dataset

Murphy, A. E.; Fancy, N.; Skene, N. G.

10.1101/2023.04.01.535040 — neuroscience — Posted on 2023-06-14

2414 Musical pitch has multiple psychological geometries

Marjieh, R.; Griffiths, T. L.; Jacoby, N.

10.1101/2023.06.13.544763 — neuroscience — Posted on 2023-06-14

2415 Cell morphology best predicts tumorigenicity and metastasis in vivo across multiple TNBC cell lines of different metastatic potential

Conner, S. J.; Guarin, J. R.; Le, T. T.; Fatherree, J. P.; Kelley, C. A.; Payne, S. L.; Salhany, K.; McGinn, R. A.; Henrich, E.; Yui, A.; Parker, S. R.; Srinivasan, D.; Bloomer, H.; Borges, H.; Oudin, M. J.

10.1101/2023.06.14.544969 — cancer biology — Posted on 2023-06-14

2416 Single Cell Track and Trace: live cell labelling and temporal transcriptomics via nanobiopsy.

Marcuccio, F.; Chau, C. C.; Tanner, G.; Elpidorou, M.; Finetti, M.; Ajaib, S.; Taylor, M.; Lascelles, C.; Carr, I. M.; Macaulay, I. C.; Stead, L. F.; Actis, P.

10.1101/2023.06.13.544323 — genomics — Posted on 2023-06-14

2417 Haplotype-resolved, chromosome-level assembly of white clover (Trifolium repens L., Fabaceae)

Santangelo, J.; Battlay, P.; Hendrickson, B.; Kuo, W.-H.; Olsen, K. M.; Kooyers, N. J.; Johnson, M.; Hodgins, K.; Ness, R.

10.1101/2023.06.06.543960 — genomics — Posted on 2023-06-14

2418 Specific genomic targeting of the RNF12/RLIM E3 ubiquitin ligase selectively programmes developmental transcription

Espejo-Serrano, C.; Aitken, C.; Tan, B. F.; May, D. G.; Chrisopulos, R. J.; Roux, K. J.; Mackintosh, S. G.; Gribnau, J.; Bustos, F.; Gontan, C.; Findlay, G. M.

10.1101/2023.06.14.544957 — cell biology — Posted on 2023-06-14

2419 Assessing the Dose-Dependent Effects of tDCS on Neurometabolites using Magnetic Resonance Spectroscopy

Shinde, A.; Nagarajan, R.; Gunduz, M. E.; Visintainer, P.; Schlaug, G.

10.1101/2023.06.13.544864 — neuroscience — Posted on 2023-06-14

2420 Brain structure reflects empathy and psychopathy in incarcerated males

Radecki, M. A.; Sampaolo, E.; Lettieri, G.; Handjaras, G.; Harenski, C. L.; Palumbo, S.; Pellegrini, S.; Pietrini, P.; Kiehl, K. A.; Cecchetti, L.

10.1101/2023.06.14.543399 — neuroscience — Posted on 2023-06-14

2421 Consideration of sex as a biological variable in diabetes research across twenty years

Cherian, C. M.; Reeves, H.; De Silva, D.; Tsao, S.; Marshall, K. E.; Rideout, E. J.

10.1101/2023.06.13.544882 — scientific communication and education — Posted on 2023-06-14

2422 UniSpec: A Deep Learning Approach for Predicting Energy-Sensitive Peptide Tandem Mass Spectra and Generating Proteomics-Wide In-Silico Spectral Libraries

Lapin, J.; Yan, X.; Dong, Q.

10.1101/2023.06.14.544947 — bioinformatics — Posted on 2023-06-14

2423 Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by minor groove anchor competition

Kobayashi, W.; Sappler, A.; Bollschweiler, D.; Kümmecke, M.; Basquin, J.; Nur Arslantas, E.; Ruangroengkulrith, S.; Hornberger, R.; Duderstadt, K.; Tachibana, K.

10.1101/2023.06.14.544949 — biochemistry — Posted on 2023-06-14

2424 Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

Laboy, R.; Ndoci, M.; Vonolfen, M.; Ballhysa, E.; Atanassov, I.; Antebi, A.

10.1101/2023.06.14.544948 — cell biology — Posted on 2023-06-14

2425 Macromolecular Crowding Tailors the Microtubule Cytoskeleton Through Tubulin Modifications and Microtubule-Associated Proteins

Shen, Y.; Ori-McKenney, K. M.

10.1101/2023.06.14.544846 — cell biology — Posted on 2023-06-14

2426 Multielectrode Network Stimulation (ME-NETS) demonstrated by concurrent tDCS and fMRI

Ross, D.; Shinde, A.; Lerud, K.; Schlaug, G.

10.1101/2023.06.13.544867 — neuroscience — Posted on 2023-06-14

2427 Harmonization techniques for machine learning studies using multi-site functional MRI data

El-Gazzar, A.; Thomas, R. M.; van Wingen, G.

10.1101/2023.06.14.544758 — neuroscience — Posted on 2023-06-14

2428 The Size of Fields in Biomedical Sciences

Dragotakes, Q.; Casadevall, A.

10.1101/2023.06.13.544650 — systems biology — Posted on 2023-06-14

2429 Endocrine pancreas-specific Gclc gene deletion causes a severe diabetes phenotype

Davidson, E. A.; Chen, Y.; Singh, S.; Orlicky, D. J.; Thompson, B.; Wang, Y.; Charkoftaki, G.; Furnary, T.; Cardone, R.; Kibbey, R. G.; Shearn, C. T.; Nebert, D. W.; Thompson, D. C.; Vasiliou, V.

10.1101/2023.06.13.544855 — physiology — Posted on 2023-06-14

2430 High-fat diet-induced obesity increases susceptibility to endogenous and ethyl carbamate-induced somatic mutagenesis

Lichtler, R.; Wilson, M. J.; Wickliffe, J. K.

10.1101/2023.06.14.543760 — pharmacology and toxicology — Posted on 2023-06-14

2431 Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer

Koo, J.; Seong, C.-S.; Parker, R. E.; Dwivedi, B.; Arthur, R. A.; Dinasarapu, A. R.; Johnston, H. R.; Claussen, H.; Tucker-Burden, C.; Ramalingam, S. S.; Fu, H.; Zhou, W.; Marcus, A. I.; Gilbert-Ross, M.

10.1101/2023.06.14.544941 — cancer biology — Posted on 2023-06-14

2432 An inducible germ cell ablation chicken model for high-grade germline chimeras

Chen, Y.-C.; Saito, D.; Suzuki, T.; Takemoto, T.

10.1101/2023.06.14.544953 — bioengineering — Posted on 2023-06-14

2433 An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

Cui, G.; Botuyan, M. V.; Drane, P.; Hu, Q.; Bragantini, B.; Thompson, J. R.; Schuller, D. J.; Detappe, A.; Perfetti, M. T.; James, L. I.; Frye, S. V.; Chowdhury, D.; Mer, G.

10.1101/2023.04.20.534960 — biochemistry — Posted on 2023-06-14

2434 SNPLift: Fast and accurate conversion of genetic variant coordinates across genome assemblies

Normandeau, E.; de Ronne, M.; Torkamaneh, D.

10.1101/2023.06.13.544861 — genomics — Posted on 2023-06-14

2435 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

10.1101/2023.06.10.544434 — genomics — Posted on 2023-06-14

2436 Evaluating key evidence and formulating regulatory alternatives regarding the UK Hunting Trophies (Import Prohibition) Bill

Challender, D.; 't Sas-Rolfes, M.; Dickman, A.; Hare, D.; Hart, A.; Hoffmann, M.; Mallon, D.; Mandisodza-Chikerema, R.; Roe, D.

10.1101/2023.06.13.544826 — ecology — Posted on 2023-06-14

2437 Catch me if you can: current status and topical issues on the use of eDNA-based targeted detection of rare and endangered animal species

Duarte, S.; Simoes, L.; Costa, F. O.

10.1101/2023.06.13.544783 — ecology — Posted on 2023-06-14

2438 Profiling the neuroimmune cascade in 3xTg mice exposed to successive mild traumatic brain injuries

Pybus, A. F.; Bitarafan, S.; Brothers, R. O.; Rohrer, A.; Khaitan, A.; Rivera, F.; Udeshi, K.; Davies, B.; Triplett, S.; Dammer, E. B.; Rangaraju, S.; Buckley, E. M.; Wood, L. B.

10.1101/2023.06.13.544838 — neuroscience — Posted on 2023-06-14

2439 Individual differences in time-varying and stationary brain connectivity during movie watching from childhood to early adulthood: age, sex, and behavioral associations

Di, X.; Xu, T.; Uddin, L. Q.; Biswal, B. B.

10.1101/2023.01.30.526311 — neuroscience — Posted on 2023-06-14

2440 Not only a matter of age: Machine learning-based characterization of the differential effect of brain stimulation on skill acquisition

Maceira-Elvira, P.; Popa, T.; Schmid, A.-C.; Cadic-Melchior, A.; Müller, H.; Schaer, R.; Cohen, L. G.; Hummel, F. C.

10.1101/2023.06.14.544579 — neuroscience — Posted on 2023-06-14

2441 Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

Gupta, P.; Herring, B.; Kumar, N.; Telange, R.; Garcia-Buntley, S.; Caceres, T.; Colantonio, S.; Williams, F.; Kurup, P.; M. Carter, A.; Lin, D.; Chen, H.; Rose, B.; Jaskula-Sztul, R.; Mukhtar, M. S.; Reddy, S.; A. Bibb, J.

10.1101/2023.06.13.544755 — cancer biology — Posted on 2023-06-14

2442 Protein arginine methyltransferase 5 (Prmt5) localizes to chromatin loop anchors and modulates expression of genes at TAD boundaries during early adipogenesis

Syed, S. A.; Shqillo, K.; Nand, A.; Zhan, Y.; Dekker, J.; Imbalzano, A. N.

10.1101/2023.06.13.544859 — genomics — Posted on 2023-06-14

2443 Phylogenetic and population structure of the nod-free but nodulating Bradyrhizobium phylogroup

Ling, L.; Camuel, A.; Wang, S.; Wang, X.; Lin, X.; Nouwen, N.; Giraud, E.; Luo, H.

10.1101/2023.06.14.544914 — genomics — Posted on 2023-06-14

2444 Subpopulations of corticotropin-releasing factor containing neurons and internal circuits in the chicken central extended amygdala

Pross, A.; Metwalli, A. H.; Abellan, A.; Desfilis, E.; Medina, L.

10.1101/2023.06.08.544245 — neuroscience — Posted on 2023-06-14

2445 Optimal Filters for ERP Research II: Recommended Settings for Seven Common ERP Components

Zhang, G.; Garrett, D. R.; Luck, S. J.

10.1101/2023.06.13.544794 — neuroscience — Posted on 2023-06-14

2446 Musashi-2 (MSI2) regulation of DNA damage response in lung cancer

Bychkov, I.; Deneka, A.; Topchu, I.; Pangeni, R. P.; Lengner, C.; Karanicolas, J.; Golemis, E. A.; Makhov, P.; Boumber, Y.

10.1101/2023.06.13.544756 — cancer biology — Posted on 2023-06-14

2447 Genetic Gains in IRRIs Rice Salinity Breeding and Elite Panel Development as a Future Breeding Resource

Khanna, A.; Ramos, J.; Sta. Cruz, M. T.; Catolos, M.; Anumalla, M.; Sajise, A. G.; Gregorio, G. B.; Singh, R. K.; Dixit, S.; Ali, J.; Islam, M. R.; Singh, V. K.; Rahman, A.; Khatun, H.; Pisano, D. J.; Bhosale, S.; Hussain, W.

10.1101/2023.06.14.544895 — genetics — Posted on 2023-06-14

2448 Including the Invisible Fraction in Whole Population Studies: a Guide to the Genetic Sampling of Unhatched Bird Eggs

Morland, F.; Santure, A. W.; Patel, S.; Brekke, P.; Hemmings, N.

10.1101/2023.06.13.544703 — genetics — Posted on 2023-06-14

2449 Method to determine whether sleep phenotypes are driven by endogenous circadian rhythmicity or environmental light by combining longitudinal data and personalised mathematical models

Skeldon, A. C.; Rodriguez Garcia, T.; Cleator, S. F.; della Monica, C.; Ravindran, K. K. G.; Revell, V. L.; Dijk, D.-J.

10.1101/2023.06.14.544757 — neuroscience — Posted on 2023-06-14

2450 Evaluating Minocycline as a Neuroprotective Agent in an Aged Female Rat MCAO Stroke Model

Gutierrez, L.; Tutino, V. M.; Siddiqui, A. H.

10.1101/2023.06.13.544795 — neuroscience — Posted on 2023-06-14

2451 Paracrine secretion of MUFAs prevents ferroptosis in triple-negative breast cancer and reveals selenocysteine synthesis dependency for lung metastasis

Ackermann, T.; Shokry, E.; Deshmukh, R.; Anand, J.; Galbraith, L. C. A.; Mitchell, L.; Rodriguez-Blanco, G.; Villar, V. H.; Sterken, B. A.; Nixon, C.; Zanivan, S.; Blyth, K.; Sumpton, D.; Tardito, S.

10.1101/2023.06.13.544588 — cancer biology — Posted on 2023-06-14

2452 Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis

Momeny, M.; Tienhaara, M.; Chakroborty, D.; Sharma, M.; Varjus, R.; Merisaari, J.; Padzik, A.; Vogt, A.; Paatero, I.; Kurppa, K.; Elenius, K.; Laajala, T. D.; Westermarck, J.

10.1101/2023.06.14.544493 — cancer biology — Posted on 2023-06-14

2453 Polygenic adaptation to overnutrition reveals a role for cholinergic signaling in longevity

Rundell, T. B.; Brunelli, M.; Alvi, A.; Safian, G.; Capobianco, C.; Tu, W.; Subedi, S.; Fiumera, A.; Musselman, L. P.

10.1101/2023.06.14.544888 — genetics — Posted on 2023-06-14

2454 Different gametogenesis states uniquely impact longevity in Caenorhabditis elegans.

Chaturbedi, A.; Lee, S. S.

10.1101/2023.06.13.544885 — genetics — Posted on 2023-06-14

2455 Influence of colour vision on attention to, and impression of, complex aesthetic images

Hiramatsu, C.; Takashima, T.; Sakaguchi, H.; Chen, X.; Tajima, S.; Seno, T.; Kawamura, S.

10.1101/2023.06.14.544891 — neuroscience — Posted on 2023-06-14

2456 Acute stress reshapes third-party punishment and help decisions: Behavioral evidence and neurocomputational mechanisms

Wang, H.; Wu, X.; Xu, J.; Zhu, R.; Zhang, S.; Xu, Z.; Mai, X.; Liu, C.; Qin, S.

10.1101/2023.06.14.544887 — neuroscience — Posted on 2023-06-14

2457 Reliable, standardized measurements for cell mechanical properties

Perez-Dominguez, S.; Kulkarni, S. G.; Pabijan, J.; Gnanachandran, K.; Holuigue, H.; Eroles, M.; Lorenc, E.; Berardi, M.; Antonovaite, N.; Marini, M. L.; Lopez Alonso, J.; Redonto-Morata, L.; Dupres, V.; Janel, S.; Acharya, S.; Otero, J.; Navajas, D.; Bielawski, K.; Schillers, H.; Lafont, F.; Rico, F.; Podesta, A.; Radmacher, M.; Lekka, M.

10.1101/2023.06.14.544753 — biophysics — Posted on 2023-06-14

2458 The molecular architecture of the desmosomal outer dense plaque by integrative structural modeling

Pasani, S.; Menon, K. S.; Viswanath, S.

10.1101/2023.06.13.544884 — biophysics — Posted on 2023-06-14

2459 Spontaneous rotations in epithelia as an interplay between cell polarity and boundaries.

Lo Vecchio, S.; Pertz, O.; Szopos, M.; Navoret, L.; Riveline, D.

10.1101/2021.11.11.468187 — biophysics — Posted on 2023-06-14

2460 Widespread but spotty: Atlantic cod is a complex of five species through ecological speciation.

Halldorsdottir, K.; Llanos-Garrido, A.; Einarsson, A. W.; Sackton, T. B.; Arnason, E.

10.1101/2023.06.14.544921 — evolutionary biology — Posted on 2023-06-14

2461 Neutral sequence evolution in short introns of Drosophila melanogaster

Yildirim, B.; Vogl, C.

10.1101/2023.06.14.544886 — evolutionary biology — Posted on 2023-06-14

2462 Motor control and adaptation in a redundant motor task manipulating a stick with both hands

Kobayashi, T.; Nozaki, D.

10.1101/2023.06.13.544873 — neuroscience — Posted on 2023-06-14

2463 BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer's disease and related dementias

Yin, T.; D'Adamio, L.

10.1101/2023.06.14.544924 — neuroscience — Posted on 2023-06-14

2464 Universal predictive scaling laws of phase separation of prion-like low complexity domains

Maristany, M. J.; Aguirre Gonzalez, A.; Collepardo-Guevara, R.; Joseph, J. A.

10.1101/2023.06.14.543914 — biophysics — Posted on 2023-06-14

2465 Predicting the placement of biomolecular structures on AFM substrates based on electrostatic interactions

Amyot, R.; Kodera, N.; Flechsig, H.

10.1101/2023.06.13.544749 — biophysics — Posted on 2023-06-14

2466 ontophylo: Reconstructing the evolutionary dynamics of phenomes using new ontology-informed phylogenetic methods

Sasso Porto, D.; Uyeda, J.; Miko, I.; Tarasov, S.

10.1101/2023.06.13.544734 — evolutionary biology — Posted on 2023-06-14

2467 Evidence for a chromosomal inversion maintaining divergent plumage phenotypes between extensively hybridizing yellowhammers (Emberiza citrinella) and pine buntings (E. leucocephalos)

Nikelski, E.; Rubtsov, A. S.; Irwin, D.

10.1101/2023.06.13.544781 — evolutionary biology — Posted on 2023-06-14

2468 Reduced mammillary body volume in individuals with a schizophrenia diagnosis: an analysis of the COBRE data set

Milczarek, M.; Gilani, S.; Lequin, M.; Vann, S.

10.1101/2023.06.13.544746 — neuroscience — Posted on 2023-06-14

2469 Cortical Activity Associated With Acute Development of Phantom Auditory Percepts via Unilateral Deprivation

Ginnan, G.; Rampp, S.; Schaette, R.; Buchfelder, M.; Mueller-Voggel, N.

10.1101/2023.06.13.544737 — neuroscience — Posted on 2023-06-14

2470 Development of an in situ cell-type specific proteome analysis method using antibody-mediated biotinylation

Ryu, T.; Kim, S.-Y.; Thuraisamy, T.; Jang, Y.; Na, C. H.

10.1101/2023.06.13.544682 — systems biology — Posted on 2023-06-14

2471 Impact of inoculation practices on microbiota assembly and community stability in a fabricated ecosystem

Lin, H.-H.; Torres, M.; Adams, C. A.; Andeer, P. F.; Owens, T. K.; Zhalnina, K.; Jabusch, L. K.; Carlson, H. K.; Kuehl, J. V.; Deutschbauer, A. M.; Northen, T. R.; Glass, L.; Mortimer, J. C.

10.1101/2023.06.13.544848 — plant biology — Posted on 2023-06-14

2472 Charophytic Green Algae encode ancestral Pol IV/Pol V subunits and a CLSY/DRD1 homolog

Chakraborty, T.; Trujillo, J. T.; Kendall, T.; Mosher, R. A.

10.1101/2023.06.13.544724 — plant biology — Posted on 2023-06-14

2473 Coordinated regulation of photosynthesis and translation via NIK1/RPL10/LIMYB signaling module in response to biotic and abiotic stresses

Teixiera, R. M.; Ferreira, M. A.; Brustolini, O. J. B.; Saia, T. F. F.; Jean-Baptiste, J.; Breves, S. S.; Soares, I. N.; Ribeiro, N. G. A.; Duarte, C. E. M.; Lima, L. L.; Oliveira, L. L.; Ramos, H. J. O.; dos Reis, P. A. B.; Fontes, E. P. B.

10.1101/2023.06.13.544461 — plant biology — Posted on 2023-06-14

2474 Endocrine pancreas-specific Gclc gene deletion causes a severe diabetes phenotype

Davidson, E. A.; Chen, Y.; Singh, S.; Orlicky, D. J.; Thompson, B.; Wang, Y.; Charkoftaki, G.; Furnary, T.; Cardone, R.; Kibbey, R. G.; Shearn, C. T.; Nebert, D. W.; Thompson, D. C.; Vasiliou, V.

10.1101/2023.06.13.544855 — physiology — Posted on 2023-06-14

2475 Deep Learning Glioma Grading with the Tumor Microenvironment Analysis Protocol for A Comprehensive Learning, Discovering, and Quantifying Microenvironmental Features

Pytlarz, M.; Wojnicki, K.; Pilanc, P.; Kaminska, B.; Crimi, A.

10.1101/2023.06.13.544739 — bioinformatics — Posted on 2023-06-14

2476 Biologically-informed self-supervised learning for segmentation of subcellular spatial transcriptomics data

Fu, X.; Lin, Y.; Lin, D.; Mechtersheimer, D.; Wang, C.; Ameen, F.; Ghazanfar, S.; Patrick, E.; Kim, J.; Yang, J. Y. H.

10.1101/2023.06.13.544733 — bioinformatics — Posted on 2023-06-14

2477 Spatial differences in elemental stoichiometry and essential fatty acid content of food sources and consumers in a stream food web

Torres-Ruiz, M.; Wehr, J. D.; Perrone, A. A.

10.1101/2023.06.14.544725 — ecology — Posted on 2023-06-14

2478 Can leafhoppers help us trace the impact of climate change on agriculture?

Plante, N.; Durivage, J.; Brochu, A.-S.; Dumonceaux, T.; Torres, D.; Bahder, B.; Kits, J.; Dionne, A.; Legare, J.-P.; Tellier, S.; McCune, F.; Goulet, C.; Fournier, V.; Perez-Lopez, E.

10.1101/2023.06.13.544773 — ecology — Posted on 2023-06-14

2479 The effects of prefrontal tDCS on working memory associate with the magnitude of the individual electric field in the brain

Razza, L. B.; De Smet, S.; Van Hoornweder, S.; De Witte, S.; Luethi, M.; Baeken, C.; Brunoni, A.; Vanderhasselt, M.-A.

10.1101/2023.06.13.544810 — neuroscience — Posted on 2023-06-14

2480 MNK inhibitor eFT508 (Tomivosertib) suppresses ectopic activity in human dorsal root ganglion neurons from dermatomes with radicular neuropathic pain

Li, Y.; Uhelski, M. L.; North, R. Y.; Mwirigi, J. M.; Tatsui, C. E.; Cata, J. P.; Corrales, G.; Price, T. J.; Dougherty, P. M.

10.1101/2023.06.13.544811 — neuroscience — Posted on 2023-06-14

2481 Mechanical loading of the Achilles tendon during different rehabilitation exercises: A cross sectional observational study.

New, P.; Wood, L.

10.1101/2023.06.13.544659 — physiology — Posted on 2023-06-14

2482 An Enterobacteriaceae bloom in aging animals is restrained by the gut microbiome

Choi, R.; Bodkhe, R.; Pees, B.; Kim, D. J.; Berg, M.; Monnin, D.; Cho, J.; Narayan, V.; Deller, E.; Shapira, M.

10.1101/2023.06.13.544815 — physiology — Posted on 2023-06-14

2483 SpatialView: An interactive web application forvisualization of multiple samples in spatialtranscriptomics experiments

Mohanty, C.; Prasad, A.; Cheng, L.; Arkin, L. M.; Shields, B. E.; Drolet, B.; Kendziorski, C.

10.1101/2023.06.13.544836 — bioinformatics — Posted on 2023-06-14

2484 MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data

Browaeys, R.; Gilis, J.; Sang-Aram, C.; De Bleser, P.; Hoste, L.; Tavernier, S. J.; Lambrechts, D.; Seurinck, R.; Saeys, Y.

10.1101/2023.06.13.544751 — bioinformatics — Posted on 2023-06-14

2485 Climate benefits of seaweed farming: estimating regional carbon emission and sequestration pathways

Bullen, C.; Driscoll, J.; Burt, J.; Stephens, T.; Hessing-Lewis, M.; Gregr, E. J.

10.1101/2023.06.13.544854 — ecology — Posted on 2023-06-14

2486 Tree demographic strategies largely overlap across succession in Neotropical wet and dry forest communities

Schorn, M. E.; Kambach, S.; Chazdon, R. L.; Craven, D.; Farrior, C. E.; Meave, J. A.; Munoz, R.; van Breugel, M.; Amissah, L.; Bongers, F.; Herault, B.; Jakovac, C. C.; Norden, N.; Poorter, L.; van der Sande, M. T.; Wirth, C.; Delgado, D.; Dent, D. H.; DeWalt, S. J.; Dupuy, J. M.; Finegan, B.; Hall, J. S.; Hernandez-Stefanoni, J.-L.; Lopez, O. R.; Rueger, N.

10.1101/2023.06.14.544754 — ecology — Posted on 2023-06-14

2487 Aberrant cortical activity, functional connectivity, and neural assembly architecture after photothrombotic stroke in mice

Bandet, M. V.; Winship, I. R.

10.1101/2023.06.13.544847 — neuroscience — Posted on 2023-06-14

2488 An information-theoretic quantification of the content of communication between brain regions

Celotto, M.; Bim, J.; Tlaie, A.; De Feo, V.; Lemke, S. M.; Chicharro, D.; Nili, H.; Bieler, M.; Hanganu-Opatz, I.; Donner, T. H.; Brovelli, A.; Panzeri, S.

10.1101/2023.06.14.544903 — neuroscience — Posted on 2023-06-14

2489 Brain mitochondrial diversity and network organization predict anxiety-like behavior in mice

Rosenberg, A. M.; Saggar, M.; Monzel, A. S.; Devine, J.; Rogu, P.; Limoges, A.; Junker, A.; Sandi, C.; Mosharov, E. V.; Dumitriu, D.; Anacker, C.; Picard, M.

10.1101/2021.06.02.446767 — neuroscience — Posted on 2023-06-14

2490 Sex disparities in age-related neuromuscular decline: unveiling female susceptibility from early to late elderly

Guo, Y.; Jones, E. J.; Smart, T.; Altheyab, A.; Gamage, N.; Stashuk, D.; Piasecki, J.; Phillips, B.; Atherton, P.; Piasecki, M.

10.1101/2023.06.13.544761 — physiology — Posted on 2023-06-14

2491 Three-dimensional anatomy of the early Eocene {dagger}Whitephippus (Teleostei: Lampriformes) documents parallel conquests of the pelagic environment by multiple teleost lineages

Davesne, D.; Andrews, J. V.; Beckett, H. T.; Giles, S.; Friedman, M.

10.1101/2023.06.13.544748 — paleontology — Posted on 2023-06-14

2492 SnakeFace: a transfer learning based app for snake classification

Pires, J. G.

10.1101/2023.06.13.544741 — bioinformatics — Posted on 2023-06-14

2493 The impacts of active and self-supervised learning on efficient annotation of single-cell expression data

Geuenich, M. J.; Gong, D.-w.; Campbell, K. R.

10.1101/2023.06.13.544850 — bioinformatics — Posted on 2023-06-14

2494 Liquid-liquid interface microchannels with tunable mechanical properties mimic tissue deformations during neutrophil interstitial migration in vivo

Schrope, J. H.; Horn, A.; Farooqui, M.; Li, J.; Ahmed, A.; Juang, T. D.; Li, C.; Huttenlocher, A.; Beebe, D.

10.1101/2023.06.14.544898 — bioengineering — Posted on 2023-06-14

2495 CD22L Conjugation to Insulin Attenuates Insulin-Specific B cell Activation

Apley, K. D.; Griffith, A. S.; Downes, G.; Ross, P. A.; Farrell, M. P.; Kendall, P. L.; Berkland, C. J.

10.1101/2023.06.13.544802 — bioengineering — Posted on 2023-06-14

2496 Structural assembly of the bacterial essential interactome

Torrent, M.; Gomez Borrego, J.

10.1101/2023.06.14.544900 — biochemistry — Posted on 2023-06-14

2497 A large-scale study on the nocturnal behavior of African ungulates in zoos and its influencing factors

Guebert, J.; Hahn-Klimroth, M.; Dierkes, P. W.

10.1101/2023.06.13.544771 — animal behavior and cognition — Posted on 2023-06-14

2498 Evaluating key evidence and formulating regulatory alternatives regarding the UK Hunting Trophies (Import Prohibition) Bill

Challender, D.; 't Sas-Rolfes, M.; Dickman, A.; Hare, D.; Hart, A.; Hoffmann, M.; Mallon, D.; Mandisodza-Chikerema, R.; Roe, D.

10.1101/2023.06.13.544826 — ecology — Posted on 2023-06-14

2499 Local changes dominate variation in biotic homogenization and differentiation

Blowes, S.; McGill, B.; Brambilla, V.; Chow, C. F. Y.; Engel, T.; Fontrodona-Eslava, A.; Martins, I. S.; McGlinn, D.; Moyes, F.; Sagouis, A.; Shimadzu, H.; van Klink, R.; Xu, W.-B.; Gotelli, N. J.; Magurran, A.; Dornelas, M.; Chase, J.

10.1101/2022.07.05.498812 — ecology — Posted on 2023-06-14

2500 The Rapidly Evolving X-linked miR-506 Family Finetunes Spermatogenesis to Enhance Sperm Competition

Wang, Z.; Wang, Y.; Zhou, T.; Chen, S.; Morris, D.; Magalhaes, R. D. M.; Li, M.; Wang, S.; Wang, H.; Xie, Y.; McSwiggin, H.; Oliver, D.; Yuan, S.; Zheng, H.; Mohammed, J.; Lai, E. C.; McCarrey, J. R.; Yan, W.

10.1101/2023.06.14.544876 — developmental biology — Posted on 2023-06-14

2501 Temporal Changes in The Proanthocyanidins to Anthocyanins Ratio During Dormancy Associate with Bloom Time Variations in Peach

Das, P. R.; Islam, M. T.; Liu, J.; Liu, Z.; Dardick, C. D.; Sherif, S.

10.1101/2023.06.13.544853 — developmental biology — Posted on 2023-06-14

2502 Single-cell transcriptional landscapes of bovine peri-implantation development

Scatolin, G.; Ming, H.; Wang, Y.; Zhu, L.; Castillo, E.; Bondioli, K.; Jiang, Z.

10.1101/2023.06.13.544813 — developmental biology — Posted on 2023-06-14

2503 Macrophage Migration Inhibitory Factor on Apoptotic Extracellular Vesicles Regulates Compensatory Proliferation

Essien, S. A.; Ahuja, I.; Eisenhoffer, G. T.

10.1101/2023.06.14.544889 — cell biology — Posted on 2023-06-14

2504 Autonomic regions of the brainstem show a sex-specific inflammatory response to systemic neonatal lipopolysaccharide

Hedley, K. E.; Cuskelly, A.; Callister, R. J.; Horvat, J. C.; Hodgson, D. M.; Tadros, M. A.

10.1101/2023.06.14.544893 — neuroscience — Posted on 2023-06-14

2505 Ultra-high field fMRI of visual mental imagery in typical imagers and aphantasic individuals

Liu, J.; Zhan, M.; Hajhajate, D.; Spagna, A.; Dehaene, S.; Cohen, L.; Bartolomeo, P.

10.1101/2023.06.14.544909 — neuroscience — Posted on 2023-06-14

2506 Laterality defect of the heart in non-teleost fish

Huijskes, M. M.; Icardo, J. M.; Coolen, B. F.; Jensen, B.

10.1101/2023.06.13.544822 — zoology — Posted on 2023-06-14

2507 Haplotype-phased genome revealed the butylphthalide biosynthesis and hybrid origin of Ligusticum chuanxiong

Nie, B.; Chen, X.; Hou, Z.; Li, C.; Sun, W.; Ji, J.; Zang, L.; Yang, S.; Fan, P.; Zhang, W.; Li, H.; Tan, Y.; Li, W.; Wang, L.

10.1101/2023.06.13.544868 — synthetic biology — Posted on 2023-06-14

2508 Long noncoding RNAs emerge from transposon-derived antisense sequences and may contribute to infection stage-specific transposon regulation in a fungal phytopathogen

Qian, J.; Ibrahim, H.; Erz, M.; Kümmel, F.; Panstruga, R.; Kusch, S.

10.1101/2023.06.13.544723 — plant biology — Posted on 2023-06-14

2509 The Single-Cell Transcriptome Program of Nodule Development Cellular Lineages in Medicago truncatula

Pereira, W. J.; Boyd, J.; Conde, D.; Triozzi, P. M.; Balmant, K. M.; Dervinis, C.; Schmidt, H. W.; Boaventura-Novaes, C.; Chakraborty, S.; Knaack, S. A.; Gao, Y.; Feltus, F. A.; Roy, S.; Ane, J.-M.; Frugoli, J.; Kirst, M.

10.1101/2023.06.13.544787 — plant biology — Posted on 2023-06-14

2510 Super-resolution histology of paraffin-embedded samples via photonic chip-based microscopy

Villegas-Hernandez, L. E.; Dubey, V. K.; Mao, H.; Pradhan, M.; Tinguely, J.-C.; Hansen, D. H.; Acuna, S.; Zapotoczny, B.; Agarwal, K.; Nystad, M.; Acharya, G.; Fenton, K. A.; Danielsen, H. E.; Ahluwalia, B. S.

10.1101/2023.06.14.544765 — pathology — Posted on 2023-06-14

2511 A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

Hoolachan, J. M.; McCallion, E.; Sutton, E. R.; Cetin, O.; Pacheco-Torres, P.; Dimitriadi, M.; Okoh, M.; Walter, L. M.; Claus, P.; Wood, M. J.; Tonge, D. P.; Bowerman, M.

10.1101/2023.06.14.544899 — pathology — Posted on 2023-06-14

2512 Taphonomic damage obfuscates interpretation of the retroarticular region of the Asteriornis mandible

Crane, A.; Benito, J.; Chen, A.; Musser, G.; Torres, C. R.; Clarke, J. A.; Lautenschlager, S.; Ksepka, D. T.; Field, D. J.

10.1101/2023.06.13.544555 — paleontology — Posted on 2023-06-14

2513 VBCG: 20 validated bacterial core genes for phylogenomic analysis with high fidelity and resolution

Tian, R.; Imanian, B.

10.1101/2023.06.13.544823 — bioinformatics — Posted on 2023-06-14

2514 Single-cell multiome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis

Mitra, S.; Malik, R.; Wong, W.; Rahman, A.; Hartemink, A. J.; Pritykin, Y.; Dey, K. K.; Leslie, C. S.

10.1101/2023.06.13.544851 — bioinformatics — Posted on 2023-06-14

2515 Regional estimates of gross primary production applying the process-based model 3D-CMCC-FEM vs. multiple datasets

Dalmonech, D.; Chiesi, M.; Chirici, G.; Fibbi, L.; Giannetti, F.; Marano, G.; Massari, C.; Nole, A.; Vangi, E.; Xiao, J.; Collalti, A.

10.1101/2023.06.13.544712 — ecology — Posted on 2023-06-14

2516 Sensory context for coding of natural sounds in auditory cortex

Lopez Espejo, M.; David, S. V.

10.1101/2023.06.14.544866 — neuroscience — Posted on 2023-06-14

2517 Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data

Buckova, B. R.; Fraza, C.; Rehak, R.; Kolenic, M.; Beckmann, C.; Spaniel, F.; Marquand, A.; Hlinka, J.

10.1101/2023.06.09.544217 — neuroscience — Posted on 2023-06-14

2518 DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

Ma, R. K.; Tsai, P.-Y.; Farghli, A. R.; Shumway, A. J.; Kanke, M.; Gordan, J. D.; Gujral, T.; Vakili, K.; Nukaya, M.; Noetzli, L.; Ronnekleiv-Kelly, S.; Broom, W.; Barrow, J.; Sethupathy, P.

10.1101/2023.06.02.543290 — cancer biology — Posted on 2023-06-14

2519 Enhancing single-cell western blotting sensitivity using diffusive analyte blotting and antibody conjugate amplification

Long, M. A.; Benman, W.; Petrikas, N.; Bugaj, L.; Hughes, A. J.

10.1101/2023.06.13.544857 — bioengineering — Posted on 2023-06-14

2520 COGNITIVE REJUVENATION IN OLD RATS BY HIPPOCAMPAL OSKM GENE THERAPY

Horvath, S.; Lacunza, E.; Canatelli Mallat, M.; Portiansky, E. P.; Gallardo, M. D.; Brooke, R. T.; Chiavellini, P.; Pasquini, D. C.; Girard, M. G.; Lehmann, M.; Yan, Q.; Lu, A. T.; Haghani, A.; Gordevicius, J.; Abba, M. C.; Goya, R.

10.1101/2023.06.13.544719 — neuroscience — Posted on 2023-06-14

2521 Evidence for vocal signatures and voice-prints in a wild parrot

Smeele, S. Q.; Senar, J. C.; Aplin, L. M.; McElreath, M. B.

10.1101/2023.01.20.524864 — animal behavior and cognition — Posted on 2023-06-14

2522 Comparative chemical genomics in Babesia species identifies the alkaline phosphatase phoD as a novel determinant of resistance

Keroack, C. D.; Elsworth, B.; Tennessen, J. A.; Paul, A. S.; Hua, R.; Ramirez-Ramirez, L.; Ye, S.; Moreira, C. M.; Meyers, M. J.; Zarringhalam, K.; Duraisingh, M. T.

10.1101/2023.06.13.544849 — molecular biology — Posted on 2023-06-13

2523 Metabolic network construction reveals probiotic-specific alterations in the metabolic activity of a synthetic small intestinal community

Jansma, J.; Chatziioannou, A. C.; Castricum, K.; van Hemert, S.; El Aidy, S.

10.1101/2023.03.29.534679 — microbiology — Posted on 2023-06-14

2524 Anthelmintic efficacy of Holarrhena pubescens against Raillietina spp. of domestic fowl through ultrastructural, histochemical, biochemical and GLCM analysis

Saha, R.; Gupta, M.; Majumdar, R.; Saha, S.; Kar, P. K.

10.1101/2023.02.07.527541 — zoology — Posted on 2023-06-14

2525 Integrin beta4 promotes DNA damage drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/Rac1

Fang, H.; Ren, W.; Cui, Q.; Liang, H.; Yang, C.; Liu, W.; Wang, X.; Liu, X.; Shi, Y.; Feng, J.; Chen, C.

10.1101/2023.04.17.537130 — cancer biology — Posted on 2023-06-14

2526 Directed evolution of nanosensors for the detection of mycotoxins

Lambert, B. P.; Taheri, A.; Wu, S.-J.; Gillen, A. J.; Kashaninejad, M.; Boghossian, A. A.

10.1101/2023.06.13.544576 — biophysics — Posted on 2023-06-14

2527 Simulations suggest a scaffolding mechanism of membrane deformation by the caveolin 8S complex

Vasquez Rodriguez, S. Y.; Lazaridis, T.

10.1101/2023.04.20.537670 — biophysics — Posted on 2023-06-14

2528 The mineralocorticoid receptor forms higher order oligomers upon DNA binding

Fettweis, G.; Johnson, T. A.; Almeida-Prieto, B.; Presman, D. M.; Hager, G. L.; Alvarez de la Rosa, D.

10.1101/2023.01.26.525752 — biophysics — Posted on 2023-06-14

2529 A simple Turing reaction-diffusion model can explain how mother centrioles break symmetry to generate a single daughter

Wilmott, Z. W.; Goriely, A.; Raff, J. W.

10.1101/2023.02.02.526828 — cell biology — Posted on 2023-06-14

2530 An ancient respiratory enzyme metabolically modulates Fusobacterium nucleatum virulence

Britton, T. A.; Wu, C.; Chen, Y.-W.; Franklin, D.; Chen, Y.; Camacho, M. I.; Luong, T. T.; Das, A.; Ton-That, H.

10.1101/2023.06.13.544113 — microbiology — Posted on 2023-06-13

2531 Mycobiome analyses of critically ill COVID-19 patients suggests antifungal prophylaxis may be protective against A. fumigatus-associated mortality

Weaver, D.; Gago, S.; Bassetti, M.; Giacobbe, D. R.; Prattes, J.; Hoenigl, M.; Reizine, F.; Guegan, H.; Gangneux, J.-P.; Bromley, M. J.; Bowyer, P.

10.1101/2023.06.13.543274 — microbiology — Posted on 2023-06-13

2532 Distinguishing examples while building concepts in hippocampal and artificial networks

Kang, L.; Toyoizumi, T.

10.1101/2023.02.21.529365 — neuroscience — Posted on 2023-06-14

2533 Scrutinizing the protein hydration shell from molecular dynamics simulations against consensus small-angle scattering data

Linse, J.-B.; Hub, J. S.

10.1101/2023.06.13.544709 — biophysics — Posted on 2023-06-14

2534 Creativity and memory: Cortical representational change along with amygdala activation predict the insight memory effect

Becker, M.; Sommer, T.; Cabeza, R.

10.1101/2023.06.13.544774 — neuroscience — Posted on 2023-06-14

2535 Homeostasis of a representational map in the neocortex

Noda, T.; Kienle, E.; Eppler, J.-B.; Aschauer, D. F.; Kaschube, M.; Loewenstein, Y.; Rumpel, S.

10.1101/2023.06.13.544358 — neuroscience — Posted on 2023-06-14

2536 Structure-based virtual screening identifies small molecule inhibitors of O-fucosyltransferase SPINDLY

Aizezi, Y.; Zhao, H.; Zhang, Z.; Bi, Y.; Yang, Q.; Guo, G.; Zhang, H.; Guo, H.; Jiang, K.; Wang, Z.-Y.

10.1101/2023.06.13.544843 — plant biology — Posted on 2023-06-14

2537 The homeodomain drives favorable DNA binding energetics of prostate cancer target ONECUT2

Chatterjee, A.; Gallent, B.; Katiki, M.; Qian, C.; Harter, M. R.; Freeman, M. R.; Murali, R.

10.1101/2023.06.13.544830 — biophysics — Posted on 2023-06-14

2538 Dynamics in the assembly of the 30S ribosomal subunit investigated by coarse-grained simulations

Liu, X.; Zhang, Z.

10.1101/2023.06.13.544708 — biophysics — Posted on 2023-06-14

2539 Polycomb sustains promoters in a deep OFF-state by limiting PIC formation to counteract transcription

Szczurek, A. T.; Dimitrova, E.; Kelley, J. R.; Klose, R. J.

10.1101/2023.06.13.544762 — cell biology — Posted on 2023-06-14

2540 Tools for Quantitative Analysis of Calcium Signaling Data Using Jupyter-Lab Notebooks

Rugis, J.; Chaffer, J.; Sneyd, J.; Yule, D. I.

10.1101/2023.06.13.544740 — cell biology — Posted on 2023-06-14

2541 Top-down modulation in canonical cortical circuits with inhibitory short-term plasticity

Waitzmann, F.; Wu, Y. K.; Gjorgjieva, J.

10.1101/2023.06.13.544791 — neuroscience — Posted on 2023-06-14

2542 Distinct endocannabinoids specifically signal to astrocytes and neurons

Noriega-Prieto, J. A.; Falcon-Moya, R.; Eraso-Pichot, A.; B Fundazuri, U.; Guttipatti, P.; Belisle, L.; Rodriguez-Moreno, A.; van der Stelt, M.; Cheer, J.; Marsicano, G.; Kofuji, P.; Araque, A.

10.1101/2023.06.13.544877 — neuroscience — Posted on 2023-06-14

2543 Functional glycoproteomics by integrated network assembly and partitioning

Griffin, M. E.; Thompson, J. W.; Xiao, Y.; Sweredoski, M. J.; Jensen, E. H.; Koldobskaya, Y.; Schacht, A. L.; Kim, T. D.; Choudhry, P.; Lomenick, B.; Garbis, S. D.; Moradian, A.; Hsieh-Wilson, L. C.

10.1101/2023.06.13.541482 — cell biology — Posted on 2023-06-14

2544 Small Interactor of PKD2 (SIP), a novel PKD2-related single-pass transmembrane protein, is required for proteolytic processing and ciliary import of Chlamydomonas PKD2

Das, P.; Mekonnen, B.; Ingle, A. V.; Workman, E. B.; Feather, A.; Liu, P.; Lechtreck, K.

10.1101/2023.06.13.544839 — cell biology — Posted on 2023-06-14

2545 Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons

Mcllvried, L. A.; Del Rosario, J. S.; Pullen, M. Y.; Wangzhou, A.; Sheahan, T. D.; Shepherd, A. J.; Slivicki, R. A.; Lemen, J. A.; Price, T. J.; Copits, B. A.; Gereau, R. W.

10.1101/2023.06.13.544829 — neuroscience — Posted on 2023-06-14

2546 Dopamine D2 receptors in the bed nucleus of the stria terminalis modulate alcohol-related behaviors.

Pati, D.; Lee, S. I.; Conley, S. Y.; Sides, T.; Boyt, K. M.; Hunker, A. C.; Zweifel, L.; Kash, T. L.

10.1101/2023.06.13.544820 — neuroscience — Posted on 2023-06-14

2547 Latent mutations in the ancestries of alleles under selection

Fan, W.-T.; Wakeley, J.

10.1101/2023.06.13.544872 — genetics — Posted on 2023-06-14

2548 Lysinoalanine crosslinking is a conserved post-translational modification in the spirochete flagellar hook

Lynch, M. J.; Deshpande, M.; Kyrniyati, K.; Zhang, K.; James, M.; Miller, M.; Zhang, S.; Passalia, F. J.; Wunder, E. A.; Charon, N. W.; Li, C.; Crane, B. R.

10.1101/2023.06.13.544825 — microbiology — Posted on 2023-06-13

2549 Too many big promises: What is holding back cyanobacterial research and applications?

Schmelling, N. M.; Bross, M.

10.1101/2023.06.05.543618 — microbiology — Posted on 2023-06-13

2550 New T2T assembly of Cryptosporidium parvum IOWA annotated with reference genome gene identifiers

de Paula Baptista, R.; Xiao, R.; Li, Y.; Glenn, T. C.; Kissinger, J. C.

10.1101/2023.06.13.544219 — genomics — Posted on 2023-06-13

2551 Longitudinal characterization of the captive adult and tadpole Wyoming toad (Anaxyrus baxteri) microbiome

Scarberry, N.; McAdams, Z. L.; Benson, D.; Herrick, J.; Moore, B.; Ericsson, A. C.

10.1101/2023.06.13.544657 — microbiology — Posted on 2023-06-13

2552 TB-annotator: a scalable web application that allows in-depth analysis of very large sets of publicly available Mycobacterium tuberculosis complex genomes

Senelle, G.; Guyeux, C.; Refregier, G.; Sola, C.

10.1101/2023.06.12.526393 — microbiology — Posted on 2023-06-13

2553 H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas

Garcia Fabiani, M. B.; Haase, S.; Banerjee, K.; McClellan, B.; Zhu, Z.; Mujeeb, A.; Li, Y.; Yu, J.; Kadiyala, P.; Taher, A.; NUNEZ, F. J.; Alghamri, M.; Comba, A.; Mendez, F.; Nicola Candia, A. J.; Salazar, B.; Koschmann, C.; Nunez, F. M.; Edwards, M.; Qin, T.; Sartor, M.; Lowenstein, P. R.; Castro, M. G.

10.1101/2023.06.13.544658 — cancer biology — Posted on 2023-06-13

2554 NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

Takashima, K.; Lee, D.-J.; Trovero, M. F.; Rothi, M. H.; Mistry, M.; Zhang, Y.; Li, Z.; Davis, C. P.; Li, Z.; Natale, J.; Schmid, E.; Al Haddad, J.; Hoffmann, G. B.; Dietmann, S.; Sui, S. H.; Oshiumi, H.; Lieberman, J.; Greer, E. L.

10.1101/2023.06.13.544862 — cancer biology — Posted on 2023-06-13

2555 Investigation of the usefulness of liver-specific deconvolution method toward legacy data utilization

Azuma, I.; Mizuno, T.; Morita, K.; Kusuhara, H.

10.1101/2023.04.19.537436 — bioinformatics — Posted on 2023-06-13

2556 Mitogenome sequences of domestic cats demonstrate lineage expansions and dynamic mutation processes in a mitochondrial minisatellite

Patterson, E. C.; Matharu Lall, G.; Neumann, R.; Ottolini, B.; Batini, C.; Sacchini, F.; Foster, A. P.; Wetton, J. H.; Jobling, M. A.

10.1101/2023.06.13.544779 — genomics — Posted on 2023-06-13

2557 Demographic inference for spatially heterogeneous populations using long shared haplotypes

Forien, R.; Ringbauer, H.; Coop, G.

10.1101/2023.06.13.544589 — genetics — Posted on 2023-06-13

2558 Structural basis for flagellin induced NAIP5 activation.

Zhang, L.; Paidimuddala, B.; Cao, J.

10.1101/2023.06.13.544801 — immunology — Posted on 2023-06-13

2559 Dectin-1/CARD9-induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung

Aufiero, M.; Shlezinger, N.; Gjonbalaj, M.; Mills, K. A. M.; Ballabio, A.; Hohl, T. M.

10.1101/2023.06.13.544785 — immunology — Posted on 2023-06-13

2560 Co-occurring ripple oscillations facilitate neuronal interactions between cortical locations in humans

Verzhbinsky, I. A.; Rubin, D. B.; Kajfez, S.; Bu, Y.; Kelemen, J. N.; Kapitonava, A.; Williams, Z. M.; Hochberg, L. R.; Cash, S. S.; Halgren, E.

10.1101/2023.05.20.541588 — neuroscience — Posted on 2023-06-13

2561 The Time-Course of Food Representation in the Human Brain

Moerel, D.; Psihoyos, J.; Carlson, T. A.

10.1101/2023.06.06.543985 — neuroscience — Posted on 2023-06-13

2562 A constitutive model for the remodelling erythrocyte membrane skeleton during the active invasion by the malaria merozoite

Msosa, C.; Abdalrahman, T.; Franz, T.

10.1101/2023.06.13.544728 — biophysics — Posted on 2023-06-13

2563 Detuning of the Ribosome Conformational Landscape Promotes Antibiotic Resistance and Collateral Sensitivity

Mesa, P.; La Rosa, R.; Jimenez, A.; Espinosa-Portero, R.; Johansen, H. K.; Molin, S.; Montoya, G.

10.1101/2023.06.13.544509 — biophysics — Posted on 2023-06-13

2564 ALS-causing SOD1 mutations H46R and G85R form similar novel amyloid fibril structures and promote ferroptosis in cells

Wang, L.-Q.; Ma, Y.; Zhang, M.-Y.; Yuan, H.-Y.; Li, X.-N.; Zhao, K.; Xia, W.; Huang, X.; Chen, J.; Zou, L.; Li, D.; Wang, Z.; Le, W.; Liu, C.; Liang, Y.

10.1101/2023.06.13.544727 — biochemistry — Posted on 2023-06-13

2565 Hormonal steroids bind the Neisseria gonorrhoeae multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor

Hooks, G.; Ayala, J.; Beggs, G.; Perfect, J. R.; Schumacher, M.; Shafer, W. M.; Brennan, R. G.

10.1101/2023.06.13.544409 — biochemistry — Posted on 2023-06-13

2566 Label-free quantification LC-mass spectrometry proteomic analysis of blood plasma in healthy dogs

Doulidis, P. G.; Kuropka, B.; Frizzo Ramos, C.; Rodriguez Rojas, A.; Burgener, I. A.

10.1101/2023.06.13.544743 — biochemistry — Posted on 2023-06-13

2567 An adapted MS2-MCP system to visualize endogenous cytoplasmic mRNA with live imaging in Caenorhabditis elegans

Tocchini, C.; Mango, S. E.

10.1101/2023.06.13.544769 — genetics — Posted on 2023-06-13

2568 Rewiring of the epigenome and chromatin architecture by retinoic acid signaling during zebrafish embryonic development

Moreno-Onate, M.; Gallardo-Fuentes, L.; Martinez-Garcia, P. M.; Naranjo, S.; Jimenez-Gancedo, S.; Gomez-Skarmeta, J. L.; Tena, J. J.; Santos-Pereira, J. M.

10.1101/2023.06.13.544553 — developmental biology — Posted on 2023-06-13

2569 The protein phosphatase PPKL is a key regulator of daughter parasite development in Toxoplasma gondii

Yang, C.; Doud, E. H.; Sampson, E.; Arrizabalaga, G.

10.1101/2023.06.13.544803 — cell biology — Posted on 2023-06-13

2570 Per-ischemic changes in penumbral blood supply and its microscopic distribution

Iversen, N. K.; Jimenez, E. G.; Rasmussen, P. M.; Angelys, H.; Mikkelsen, I. K.; Hollyer, T. R.; Ostergaard, L.

10.1101/2023.06.07.544164 — neuroscience — Posted on 2023-06-13

2571 Inhibition of CPEB3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory

Chen, C. C.; Han, J.; Chinn, C. A.; Rounds, J. S.; Li, X.; Nikan, M.; Myszka, M.; Tong, L.; Passalacqua, L. F. M.; Bredy, T. W.; Wood, M. A.; Luptak, A.

10.1101/2023.06.07.543953 — neuroscience — Posted on 2023-06-13

2572 CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males.

Smidler, A. L.; Paton, D. G.; Church, G. M.; Shaw, W. R.; Catteruccia, F.

10.1101/2023.06.13.544841 — synthetic biology — Posted on 2023-06-13

2573 Synthetic gene circuits combining CRISPR interference and CRISPR activation in E. coli: importance of equal guide RNA binding affinities to avoid context-dependent effects

Barbier, I.; Kusumawardhani, H.; Chauhan, L.; Harlapur, P. V.; Jolly, M. K.; Schaerli, Y.

10.1101/2023.06.13.544730 — synthetic biology — Posted on 2023-06-13

2574 Engineering of Robust Host Strains: Enhancing Escherichia coli Abiotic Stress Resistance through Ornithine Lipid Formation

Bedoya-Perez, L. P.; Aguilar-Vera, A.; Utrilla, J.; Sohlenkamp, C.

10.1101/2023.06.13.544863 — synthetic biology — Posted on 2023-06-13

2575 Targeting staphylococcal cell-wall biosynthesis protein FemX through steered molecular dynamics and drug-repurposing approach

Rahman, S.; Nath, S.; Mohan, U.; Das, A. K.

10.1101/2023.06.13.544722 — pharmacology and toxicology — Posted on 2023-06-13

2576 WNT4 regulates cellular metabolism via intracellular activity at the mitochondria in breast and gynecologic cancers

Sottnik, J. L.; Shackleford, M. T.; Villagomez, F. R.; Bahnassy, S.; Oesterreich, S.; Hu, J.; Madak-Erdogan, Z.; Riggins, R. B.; Corr, B. R.; Cook, L. S.; Trevino, L. S.; Bitler, B. G.; Sikora, M. J.

10.1101/2022.07.15.499747 — cancer biology — Posted on 2023-06-13

2577 Compressive constraint promotes the cytotoxicity of PI3K signal targeted therapies in breast and pancreatic cancer cells

Di-Luoffo, M.; Schmitter, C.; Barrere, E.; Therville, N.; Chaouki, M.; D'Angelo, R.; Thibault, B.; Delarue, M.; Guillermet-Guibert, J.

10.1101/2021.10.18.464825 — cancer biology — Posted on 2023-06-13

2578 Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers

Kim, J. M.; Carcamo, C. C.; Jazani, S.; Xie, Z.; Feng, X. A.; Poyton, M. F.; Holland, K. L.; Grimm, J. B.; Lavis, L. D.; Ha, T.; Wu, C.

10.1101/2023.06.13.544671 — biophysics — Posted on 2023-06-13

2579 Saturating the eQTL map in Drosophila melanogaster: genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations

Pallares, L. F.; Melo, D.; Wolf, S.; Cofer, E. M.; Abhyankar, V.; Peng, J.; Ayroles, J. F.

10.1101/2023.05.20.541576 — genomics — Posted on 2023-06-13

2580 SARS CoV-2 Envelope protein alters calcium signaling via SERCA interactions

Berta, B.; Tordai, H.; Lukacs, G. L.; Papp, B.; Enyedi, A.; Padanyi, R.; Hegedus, T.

10.1101/2023.06.13.544745 — cell biology — Posted on 2023-06-13

2581 C1q Enables Influenza HA Stem Binding Antibodies to Block Viral Attachment and Broadens the Antibody Escape Repertoire

Kosik, I.; Santos, J. D. S.; Angel, M.; Hu, Z.; Holly, J.; Gibbs, J. S.; Gill, T. U.; Kosikova, M.; Li, T.; Bakhache, W.; Dolan, P. T.; Xie, H.; Andrews, S. F.; Gillespie, R. A.; Kanekiyo, M.; McDermott, A. B.; Pierson, T. C.; yewdell, j.

10.1101/2023.06.12.544648 — microbiology — Posted on 2023-06-13

2582 Natural monobacterial environments modulate viral infection in Caenorhabditis elegans

Gonzalez, R.; Felix, M.-A.

10.1101/2023.06.13.544807 — microbiology — Posted on 2023-06-13

2583 Stem cell memory EBV-specific T cells control post-transplant lymphoproliferative disease and persist in vivo

Palianina, D.; Mietz, J.; Stuehler, C.; Arnold, B.; Bantug, G. R.; Münz, C.; Chijioke, O.; Khanna, N.

10.1101/2023.05.30.542809 — immunology — Posted on 2023-06-13

2584 Brain-wide measurement of protein turnover with high spatial and temporal resolution

Mohar, B.; Grimm, J. B.; Patel, R.; Brown, T. A.; Tillberg, P.; Lavis, L. D.; Spruston, N.; Svoboda, K.

10.1101/2022.11.12.516226 — neuroscience — Posted on 2023-06-13

2585 Conflicts are represented in a cognitive space to reconcile domain-general and domain-specific cognitive control

Yang, G.; Wu, H.; Li, Q.; Liu, X.; Fu, Z.; Jiang, J.

10.1101/2023.02.13.528292 — neuroscience — Posted on 2023-06-13

2586 Spatio-temporal mechanisms of consolidation, recall and reconsolidation in reward-related memory trace

Hamed, A.; Kursa, M. B.; Karwicka, W.; Piwonski, K. P.; Falinska, M.; Danielewski, K.; Rejmak-Kozicka, E.; Wlodkowska, U.; Kubik, S.; Czajkowski, R.

10.1101/2023.06.12.544632 — neuroscience — Posted on 2023-06-13

2587 Entanglement in living systems

Day, T. C.; Zamani-Dahaj, A.; Bozdag, G. O.; Burnetti, A. J.; Bingham, E. P.; Conlin, P. L.; Ratcliff, W. C.; Yunker, P. J.

10.1101/2023.06.13.544814 — biophysics — Posted on 2023-06-13

2588 BNP-Track: A framework for superresolved tracking

Sgouralis, I.; Xu, L. W. Q.; Jalihal, A. P.; Walter, N. G.; Presse, S.

10.1101/2023.04.03.535459 — biophysics — Posted on 2023-06-13

2589 Scalable, cell type-selective in vivo AAV-based CRISPR screens in mice

Ramani, B.; Rose, I. V. L.; Pan, A.; Tian, R.; Ma, K.; Palop, J. J.; Kampmann, M.

10.1101/2023.06.13.544831 — genomics — Posted on 2023-06-13

2590 A multiplexed RT-PCR Assay for Nanopore Whole Genome Sequencing of Tilapia lake virus (TiLV)

Delamare-Deboutteville, J.; Watcharachai, M.; Pimsannil, K.; Sangpo, P.; Gan, H. M.; Mohan, C. V.; Dong, H. T.; Senapin, S.

10.1101/2023.04.24.537954 — genomics — Posted on 2023-06-13

2591 How many variables does Wordclim have, really? Generative A.I. unravels the intrinsic dimension of bioclimatic variables.

Dinnage, R.

10.1101/2023.06.12.544623 — ecology — Posted on 2023-06-13

2592 Environmental determinants of round goby invasion refuges at a river scale: implications for conservation of native biodiversity

Morissette, O.; Charette, C.; Windle, M.; Francis, A.; Drouin, A.; Goldsmit, J.; Derry, A. M.

10.1101/2022.09.07.506921 — ecology — Posted on 2023-06-13

2593 Highly precise genome editing using enhanced CRISPR-Cas12a nickase module

Lee, S. H.; Kim, C. H.; Kim, H.; Lee, Y.; Lee, H.; Lim, K.-S.; Park, S. J.; Huh, J.-W.; Kim, Y.-H.; Lee, D.-S.; Kim, K. M.; Hur, J. K.

10.1101/2022.08.27.505535 — molecular biology — Posted on 2023-06-13

2594 The dynamics of phage predation on a microcolony

Eriksen, R. S.; Larsen, F. A. N.; Svenningsen, S. L.; Sneppen, K.; Mitarai, N.

10.1101/2023.06.13.544539 — microbiology — Posted on 2023-06-13

2595 Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors.

Li, W.; Nakano, T.; Mizutani, K.; Matsubara, T.; Kawatani, M.; Mukai, Y.; Danjo, T.; Yamanaka, A.; Ito, H.; Aizawa, H.; Petersen, C. C.; Yoshimoto, J.; Yamashita, T.

10.1101/2022.10.28.514159 — neuroscience — Posted on 2023-06-13

2596 Electrical synapse formation is differentially regulated by distinct isoforms of a postsynaptic scaffold

Michel, J. C.; Grivette, M. M. B.; Harshfield, A. T.; Huynh, L.; Komons, A. P.; Loomis, B.; McKinnis, K.; Miller, B. T.; Nguyen, E. Q.; Huang, T. W.; Lauf, S.; Michel, E. S.; Michel, M. E.; Marsh, A. J.; Kaye, L. E.; Lasseigne, A. M.; Lukowicz-Bedford, R. M.; Farnsworth, D. R.; Martin, E. A.; Miller, A. C.

10.1101/2022.06.27.497867 — neuroscience — Posted on 2023-06-13

2597 Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

Schmidt, M.; Lee, N.; Zhan, C.; Roberts, J. B.; Nava, A. A.; Keiser, L.; Vilchez, A.; Chen, Y.; Petzold, C. J.; Haushalter, R. W.; Blank, L. M.; Keasling, J. D.

10.1101/2023.06.13.544731 — synthetic biology — Posted on 2023-06-13

2598 Predicting glycan structure from tandem mass spectrometry via deep learning

Urban, J.; Jin, C.; Thomsson, K. A.; Karlsson, N. G.; Ives, C. M.; Fadda, E.; Bojar, D.

10.1101/2023.06.13.544793 — bioinformatics — Posted on 2023-06-13

2599 Dissection and Integration of Bursty TranscriptionalDynamics for Complex Systems

Gao, C. F.; Vaikuntanathan, S.; Riesenfeld, S.

10.1101/2023.06.13.544828 — bioinformatics — Posted on 2023-06-13

2600 Native nanoproteomics captures the structure and dynamics of endogenous protein complexes in human heart tissue

Chapman, E. A.; Roberts, D. S.; Tiambeng, T. N.; Andrews, J.; Wang, M.-D.; Reasoner, E. A.; Melby, J. A.; Li, B. H.; Kim, D.; Alpert, A. J.; Jin, S.; Ge, Y.

10.1101/2023.06.13.544817 — biochemistry — Posted on 2023-06-13

2601 Resource competition can explain simplicity in microbial community assembly

Lee, H.; Bloxham, B.; Gore, J.

10.1101/2023.06.13.544752 — ecology — Posted on 2023-06-13

2602 Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids

Rudibaugh, T.; Keung, A. J.

10.1101/2023.06.13.544782 — cell biology — Posted on 2023-06-13

2603 A large-scale sORF screen identifies putative microproteins and provides insights into their interaction partners, localisation and function

Schlesinger, D.; Dirks, C.; Navarro, C.; Lafranchi, L.; Eirich, J.; Elsässer, S. J.

10.1101/2023.06.13.544808 — molecular biology — Posted on 2023-06-13

2604 Anoxygenic phototrophic Chloroflexota member uses a Type I reaction center

Tsuji, J. M.; Shaw, N. A.; Nagashima, S.; Venkiteswaran, J. J.; Schiff, S. L.; Watanabe, T.; Fukui, M.; Hanada, S.; Tank, M.; Neufeld, J. D.

10.1101/2020.07.07.190934 — microbiology — Posted on 2023-06-13

2605 AMPK Drives Both Glycolytic and Oxidative Metabolism in T Cells During Graft-versus-host Disease

Ramgopal, A.; Braverman, E.; Sun, L.-K.; Monlish, D.; Wittmann, C.; Ramsey, M.; Caitley, R.; Hawse, W.; Byersdorfer, C.

10.1101/2023.06.12.544686 — immunology — Posted on 2023-06-13

2606 Novel joint enrichment test demonstrates high performance in simulations and identifies cell-types with enriched expression of inflammatory bowel disease risk loci

Voda, A.-I.; Jostins-Dean, L.

10.1101/2023.06.13.544716 — genetics — Posted on 2023-06-13

2607 The orientation of choroidal macrophage polarization significantly influences the development of myopia in murine models

Hou, J.; Ikeda, S.-i.; Mori, K.; Jeong, H.; Torii, H.; Negishi, K.; Tsubota, K.; Kurihara, T.

10.1101/2023.06.12.544445 — immunology — Posted on 2023-06-13

2608 A hyperthermic seizure unleashes a surge of spreading depolarizations in Scn1a deficient mice

Aiba, I.; Ning, Y.; Noebels, J. L.

10.1101/2022.10.10.511466 — neuroscience — Posted on 2023-06-13

2609 Novel compound inhibits glycolysis, proteotoxicity, inflammation, and impairments in animal models of Alzheimer's, Huntington's, and stroke: Aging as a consequence of glycolysis

Mobbs, C.; Litke, R.; Roh, K.-H.; Yoon, Y.; Ramos, I.; Kaniskan, H.; Jin, J.; Kellner, C.

10.1101/2023.06.12.544352 — neuroscience — Posted on 2023-06-13

2610 Dissociating the Contributions of Frontal Eye Field Activity to Spatial Working Memory and Motor Preparation

Jonikaitis, D.; Noudoost, B.; Moore, T.

10.1101/2023.06.12.544653 — neuroscience — Posted on 2023-06-13

2611 Involvement of a serotonin/GLP-1 circuit in adolescent isolation-induced diabetes

Kolling, L.; Khan, K.; Balasubramanian, N.; Guo, D. F.; Rahmouni, K.; Marcinkiewcz, C.

10.1101/2023.06.12.544498 — neuroscience — Posted on 2023-06-13

2612 Dominance metric in multi-component binary phase equilibria

Qian, D.; Ausserwoger, H.; Sneideris, T.; Pappu, R. V.; Knowles, T.

10.1101/2023.06.12.544666 — biophysics — Posted on 2023-06-13

2613 Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome

Hurst, C. D.; Dunn, A. R.; Dammer, E. B.; Duong, D. M.; Seyfried, N. T.; Kaczorowski, C. C.; Johnson, E. C. B.

10.1101/2023.06.12.544646 — neuroscience — Posted on 2023-06-13

2614 Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner

Harada, M.; Capdevila, L. S.; Wilhelm, M.; Burdakov, D.; Patriarchi, T.

10.1101/2023.06.13.544720 — neuroscience — Posted on 2023-06-13

2615 Improved Quality Metrics for Association and Reproducibility in Chromatin Accessibility Data Using Mutual Information

Roth, C.; Venu, V.; Job, V.; Lubbers, N.; Sanbonmatsu, K. Y.; Steadman, C. R.; Starkenburg, S.

10.1101/2023.04.26.538354 — bioinformatics — Posted on 2023-06-13

2616 Cell source-derived variabilities in human juvenile chondrocyte-derived cell sheet cartilage regenerative effects in a nude rat chondral defect implantation model

Matsukura, K.; Kondo, M.; Metzler, N. F.; Ford, A. J.; Maak, T. G.; Hutchinson, D. T.; Wang, A. A.; Sato, M.; Grainger, D. W.; Okano, T.

10.1101/2023.05.16.540535 — bioengineering — Posted on 2023-06-13

2617 Learning the sound inventory of a complex vocal skill via an intrinsic reward

Toutounji, H.; Zai, A. T.; Tchernichovski, O.; Hahnloser, R. H. R.; Lipkind, D.

10.1101/2022.09.27.509691 — animal behavior and cognition — Posted on 2023-06-13

2618 Transcriptome analysis of peripheral blood of Schistosoma mansoni infected children from the Albert Nile region in Uganda reveals genes implicated in fibrosis pathology.

Namulondo, J.; Nyangiri, O. A.; Kimuda, M. P.; Nambala, P.; Nassuuna, J.; Egesa, M.; Nerima, B.; Biryomumaisho, S.; Mugasa, C. M.; Nabukenya, I.; Kato, D.; Elliott, A.; Noyes, H.; Tweyongyere, R.; Matovu, E.; Mulindwa, J.

10.1101/2023.06.13.544714 — genomics — Posted on 2023-06-13

2619 Robust differential expression testing for single-cell CRISPR screens at low multiplicity of infection

Barry, T.; Mason, K.; Roeder, K.; Katsevich, E.

10.1101/2023.05.15.540875 — genomics — Posted on 2023-06-13

2620 The Genetics of Aerotolerant Growth in a Naturally Reduced Genome Alphaproteobacterium

Enright, A. L.; Banta, A. B.; Ward, R. D.; Rivera Vazquez, J.; Felczak, M. M.; Wolfe, M. B.; TerAvest, M. A.; Amador-Noguez, D.; Peters, J. M.

10.1101/2023.06.12.544693 — genetics — Posted on 2023-06-13

2621 Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens

Lucantonio, F.; Li, S.; Lu, J.; Roeglin, J.; Bontempi, L.; Shields, B. C.; Zarate, C. A.; Tadross, M. R.; Pignatelli, M.

10.1101/2023.06.08.544088 — neuroscience — Posted on 2023-06-13

2622 The primacy model and the structure of olfactory space

Giaffar, H.; Shuvaev, S.; Rinberg, D.; Koulakov, A. A.

10.1101/255661 — neuroscience — Posted on 2023-06-13

2623 Brain network dynamics in transitions of consciousness reorganize according to task engagement

Kumar, S. S.; Arzi, A.; Bareham, C.; Gonzalez-Castillo, J.; Fernandez, I.; Tagliazucchi, E.; Mediano, P. A. M.; Bandettini, P. A.; Bekinschtein, T. A.

10.1101/2023.06.08.544178 — neuroscience — Posted on 2023-06-13

2624 Screening effects of HCN channel blockers on sleep/wake behavior in zebrafish

Doldur Balli, F.; Smieszek, S. P.; Keenan, B.; Zimmerman, A. J.; Veatch, O. J.; Polymeropoulos, C. M.; Birznieks, G.; Polymeropoulos, M. H.

10.1101/2023.05.05.539631 — pharmacology and toxicology — Posted on 2023-06-13

2625 Targeting Ras signaling excitability in cancer cells through combined inhibition of FAK and PI3K

Chen, C.-C.; Wang, S.; Yang, J.-M.; Huang, C.-H.

10.1101/2023.06.12.544386 — cancer biology — Posted on 2023-06-13

2626 Aquaporin-4 mediated aggregation of Alzheimer's amyloid β-peptide

Maroli, N.

10.1101/2023.02.08.527707 — biophysics — Posted on 2023-06-13

2627 Modeling soybean growth: A mixed model approach

DELATTRE, M.; Toda, Y.; Tressou, J.; Iwata, H.

10.1101/2023.06.13.544713 — genetics — Posted on 2023-06-13

2628 A frameshift variant in the melanophilin gene is associated with loss of pigment from shed skin in ball pythons (Python regius)

Lederer, I.; Shahid, B.; Dao, U. M.; Brogdon, A.; Byrtus, H.; Delva, M.; Deva, O.; Hatfield, P.; Hertz, M.; Justice, J.; Mavor, S.; Pilbeam, E.; Rice, Z.; Simpson, A.; Temar, H.; Wynn, R.; Xhangolli, J.; Graves, C. W.; Seidel, H. S.

10.1101/2023.06.09.542917 — genetics — Posted on 2023-06-13

2629 Unsupervised Machine Learning for Species Delimitation, Integrative Taxonomy, and Biodiversity Conservation

Pyron, R. A.

10.1101/2023.06.12.544639 — evolutionary biology — Posted on 2023-06-13

2630 Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females

Tam, T. H.; Zhang, W.; Tu, Y.; Hicks, J. L.; Farcas, S.; Salter, M. W.

10.1101/2023.06.13.544784 — neuroscience — Posted on 2023-06-13

2631 KV7 but not dual SK/IK channel openers inhibit the activation of colonic afferents by noxious stimuli

Bhebhe, C. N.; Higham, J. P.; Gupta, R. A.; Raine, T.; Bulmer, D. C.

10.1101/2023.06.08.544183 — neuroscience — Posted on 2023-06-13

2632 Building a genetic and epigenetic predictive model of breast cancer intrinsic subtypes using large-scale data and hierarchical structure learning

Xie, J.; Yang, B.; Li, K.; Gao, L.; Liu, X.; Xiong, Y.; Chen, W.; Xia, L. C.

10.1101/2023.06.12.544702 — bioinformatics — Posted on 2023-06-13

2633 Training deep learning models for cell image segmentation with sparse annotations

Sugawara, K.

10.1101/2023.06.13.544786 — bioinformatics — Posted on 2023-06-13

2634 Higher social tolerance is associated with more complex facial behavior in macaques

Rincon, A. V.; Waller, B. M.; Duboscq, J.; Mielke, A.; Perez, C.; Clark, P. R.; Micheletta, J.

10.1101/2022.12.07.519469 — animal behavior and cognition — Posted on 2023-06-13

2635 Exploring the Interactive Effects of Seed and Site Limitation on Recruitment Dynamics in Panicum hallii

Razzaque, S.; Juenger, T.

10.1101/2023.06.12.544673 — evolutionary biology — Posted on 2023-06-13

2636 Megafauna diversity and functional declines in Europe from the Last Interglacial (LIG) to the present

Davoli, M.; Monsarrat, S.; Pedersen, R.; Scussolini, P.; Karger, D. N.; Normand, S.; Svenning, J.-C.

10.1101/2023.06.12.544580 — ecology — Posted on 2023-06-13

2637 New resources for environmental genomics in the wild Mediterranean grass B. distachyon

Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.

10.1101/2023.06.01.543285 — ecology — Posted on 2023-06-13

2638 Mitochondria- and ER-associated actin are required for mitochondrial fusion

Gatti, P.; Schiavon, C. R.; Manor, U.; Germain, M.

10.1101/2023.06.13.544768 — cell biology — Posted on 2023-06-13

2639 Spatiotemporal organization of prefrontal norepinephrine influences neuronal activity

Glaeser-Khan, S.; Savalia, N. K.; Cressy, J.; Feng, J.; Li, Y.; Kwan, A. C.; Kaye, A. P.

10.1101/2023.06.09.544191 — neuroscience — Posted on 2023-06-13

2640 CHRNA5 links chandelier cells to protection against amyloid pathology in human aging and Alzheimer's Disease

Rybnicek, J.; Chen, Y.; Milic, M.; McLaurin, J.; De Jager, P.; Schneider, J. A.; Wang, Y.; Bennett, D. A.; Tripathy, S.; Felsky, D.; Lambe, E. K.

10.1101/2022.05.03.490491 — neuroscience — Posted on 2023-06-13

2641 Lateral frontoparietal effective connectivity differentiates and predicts state of consciousness in traumatic disorders of consciousness

Ihalainen, R.; Annen, J.; Gosseries, O.; Cardone, P.; Panda, R.; Martial, C.; Thibaut, A.; Laureys, S.; Chennu, S.

10.1101/2023.06.07.544105 — neuroscience — Posted on 2023-06-13

2642 Cholinergic Modulation Shifts the Response of CA1 Pyramidal Cells to Depolarizing Ramps via TRPM4 Channels with Potential Implications for Place Field Firing

Combe, C. L.; Upchurch, C. M.; Canavier, C. C.; Gasparini, S.

10.1101/2022.10.24.513511 — neuroscience — Posted on 2023-06-13

2643 From Hot Water to Dry Dirt: Microbes Use Cytochrome 'Nanowires' of Similar Conductivity but Different Structure

Guberman-Pfeffer, M. J.

10.1101/2023.06.12.544705 — biophysics — Posted on 2023-06-13

2644 Dominance metric in multi-component binary phase equilibria

Qian, D.; Ausserwoger, H.; Sneideris, T.; Pappu, R. V.; Knowles, T.

10.1101/2023.06.12.544666 — biophysics — Posted on 2023-06-13

2645 De novo design of anti-variant COVID-19 vaccine

Goswami, A.; Kumar, M. S.; Ullah, S.; Gore, M. M.

10.1101/2022.10.20.513049 — bioinformatics — Posted on 2023-06-13

2646 Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations

Emfinger, C.; Clark, L. E.; Yandell, B. S.; Schueler, K. L.; Simonett, S.; Stapleton, D. S.; Mitok, K.; Merrins, M. J.; Keller, M. P.; Attie, A. D.

10.1101/2022.11.26.517741 — biochemistry — Posted on 2023-06-13

2647 Groundwater redox dynamics across the terrestrial-aquatic interface of Lake Erie coastal ecosystems

Machado-Silva, F.; Weintraub, M.; Ward, N. D.; Doro, K. O.; Ehosioke, S.; Regier, P.; Thomas, S. P.; Peixoto, R.; Sandoval, L.; Forbrich, I.; Kemner, K. M.; O'Loughlin, E. J.; Setten, L.; Spanbauer, T.; Bridgeman, T.; O'Meara, T.; Rod, K. A.; Patel, K.; McDowell, N. G.; Bond-Lamberty, B. P.; Megonigal, J. P.; Rich, R.; Bailey, V. L.

10.1101/2023.06.12.544684 — ecology — Posted on 2023-06-13

2648 Blind cavefish evolved food-searching behavior without changing sensory modality compared with sighted conspecies in the dark

Kuball, K.; Fernandes, V. F. L.; Takagi, D.; Yoshizawa, M.

10.1101/2023.06.12.544672 — ecology — Posted on 2023-06-13

2649 Rictor induces AKT signaling to regulate lymphatic valve formation

Banerjee, R.; Knauer, L. A.; Iyer, D.; Barlow, S. E.; Scallan, J.; Yang, Y.

10.1101/2023.06.12.544698 — developmental biology — Posted on 2023-06-13

2650 Engineering of human myotubes toward a mature metabolic and contractile phenotype

Dreher, S. I.; Grubba, P.; von Toerne, C.; Moruzzi, A.; Maurer, J.; Goj, T.; Birkenfeld, A. L.; Peter, A.; Loskill, P.; Hauck, S.; Weigert, C.

10.1101/2023.06.12.544344 — cell biology — Posted on 2023-06-13

2651 Post-transcriptional splicing can occur in a slow-moving zone around the gene

Cote, A. J.; O'Farrell, A.; Dardani, I.; Dunagin, M.; Cote, C. J.; Wan, Y.; Bayatpour, S.; Drexler, H. L.; Alexander, K. A.; Chen, F.; Wassie, A. T.; Patel, R.; Pham, K.; Boyden, E. S.; Berger, S.; Phillips-Cremins, J.; Churchman, L. S.; Raj, A.

10.1101/2020.04.06.028092 — cell biology — Posted on 2023-06-13

2652 Discrete projections from MCH neurons mediate anti-parkinsonian effects of acupuncture

Oh, J.-Y.; Lee, H.; Jang, S.-Y.; Kim, H.; Park, G.; Serikov, A.; Jang, J.-H.; Kim, J.; Yang, S.; Sa, M.; Lee, S. E.; Han, Y.-E.; Hwang, T.-Y.; Kim, H. Y.; Lee, S. E.; Oh, S.-J.; Kim, J.; Kim, J.; Lee, C. J.; Nam, M.-H.; Park, H.-J.

10.1101/2023.06.07.543987 — neuroscience — Posted on 2023-06-13

2653 Organization of an Ascending Circuit that Conveys Flight Motor State

Cheong, H. S. J.; Boone, K. N.; Bennett, M. M.; Salman, F.; Ralston, J. D.; Hatch, K.; Allen, R. F.; Phelps, A. M.; Cook, A. P.; Phelps, J. S.; Erginkaya, M.; Lee, W.-C. A.; Card, G. M.; Daly, K. C.; Dacks, A. M.

10.1101/2023.06.07.544074 — neuroscience — Posted on 2023-06-13

2654 Impact of Bmal1 rescue and time-restricted feeding on liver and muscle proteomes during the active phase in mice

Smith, J. G.; Molendijk, J.; Blazev, R.; Chen, W. H.; Zhang, Q.; Litwin, C.; Greco, C. M.; Sassone-Corsi, P.; Munoz-Canoves, P.; Parker, B. L.; Koronowski, K. B.

10.1101/2023.06.12.544652 — systems biology — Posted on 2023-06-13

2655 Tip of the iceberg? Three novel TOPLESS interacting effectors of the gall-inducing fungus Ustilago maydis

Khan, M.; Uhse, S.; Bindics, J.; Kogelmann, B.; Nagarajan, N.; Ingole, K. D.; Djamei, A.

10.1101/2023.06.12.544640 — plant biology — Posted on 2023-06-13

2656 Quantitative Analysis of Macrophage Uptake and Retention of Fluorescent Organosilica Nanoparticles

Chou, H.-C.; Chiu, S.-J.; Hu, T.-M.

10.1101/2023.06.12.544701 — pharmacology and toxicology — Posted on 2023-06-13

2657 Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke

Nong, J.; Glassman, P. M.; Reyes-Esteves, S.; Descamps, H. C.; Shuvaev, V. V.; Kiseleva, R. Y.; Papp, T. E.; Alameh, M.-G.; Tam, Y. K.; Mui, B. L.; Omo-Lamai, S.; Zamora, M. E.; Shuvaeva, T.; Arguiri, E.; Thaiss, C. A.; Myerson, J. W.; Weissman, D.; Kasner, S. E.; Parhiz, H.; Muzykantov, V. R.; Brenner, J. S.; Marcos-Contreras, O. A.

10.1101/2023.06.12.544645 — pharmacology and toxicology — Posted on 2023-06-13

2658 Circulating Sex-specific Markers of Plaque Instability in Women and Men with Severe Carotid Atherosclerosis

Gasbarrino, K.; Zheng, H.; Daskalopoulou, S. S.

10.1101/2023.06.12.544697 — pathology — Posted on 2023-06-13

2659 TRAIL agonists rescue mice from radiation-induced lung injury

Strandberg, J.; Louie, A. D.; Lee, S.; Hahn, M.; Srinivasan, P.; George, A.; De La Cruz, A.; Zhang, L.; Borrero, L. H.; Huntington, K. E.; De La Cruz, P.; Seyhan, A. A.; Koffer, P. P.; Wazer, D. E.; DiPetrillo, T. A.; Azzoli, C. G.; Rounds, S. I.; Graff, S. L.; Abbas, A. E.; Zhou, L.; El-Deiry, W. S.

10.1101/2023.06.12.544681 — pathology — Posted on 2023-06-13

2660 Discovery of Theta Ribozymes in Gut Phages-Implications for tRNA and Alternative Genetic Coding

Kienbeck, K.; Malfertheiner, L.; Zelger-Paulus, S.; Johannsen, S.; von Mering, C.; Sigel, R. K. O.

10.1101/2023.06.13.544163 — bioinformatics — Posted on 2023-06-13

2661 refMLST: Reference-based Multilocus Sequence Typing Enables Universal Bacterial Typing

Khdhiri, M.; Thomas, E.; de Smet, C. L. M.; Chandar, P.; Madasu, V.; Chandrakumar, I.; Davidson, J. M.; Anderson, P.; Chorlton, S. D.

10.1101/2023.06.12.544669 — bioinformatics — Posted on 2023-06-13

2662 Understanding the Influence of Context on Real-World Walking Energetics

Baroudi, L.; Barton, K.; Cain, S. M.; Shorter, K. A.

10.1101/2023.06.12.544651 — animal behavior and cognition — Posted on 2023-06-13

2663 A fitness landscape instability governs the morphological diversity of tip-growing cells

Ohairwe, M. E.; Zivanovic, B. D.; Rojas, E. R.

10.1101/2023.06.12.544692 — cell biology — Posted on 2023-06-13

2664 Polarized Desmosome and Hemidesmosome Shedding via Exosomes is an Early Indicator of Outer Blood-Retina Barrier Dysfunction

Hernandez, B.; Skiba, N. P.; Ploessl, K.; Strain, M.; Grigsby, D.; Kelly, U.; Cady, M. A.; Manocha, V.; Maminishkis, A.; Watkins, T.; Miller, S. S.; Ashley-Koch, A.; Stamer, W. D.; Weber, B. H.; Rickman, C. B.; Klingeborn, M.

10.1101/2023.06.12.544677 — cell biology — Posted on 2023-06-13

2665 Spatio-temporal mechanisms of consolidation, recall and reconsolidation in reward-related memory trace

Hamed, A.; Kursa, M. B.; Karwicka, W.; Piwonski, K. P.; Falinska, M.; Danielewski, K.; Rejmak-Kozinska, E.; Wlodkowska, U.; Kubik, S.; Czajkowski, R.

10.1101/2023.06.12.544632 — neuroscience — Posted on 2023-06-13

2666 Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis

Umpierre, A. D.; Li, B.; Ayasoufi, K.; Zhao, S.; Xie, M.; Thyen, G.; Hur, B.; Zheng, J.; Liang, Y.; Wu, Z. D.; Yu, X.; Sung, J.; Johnson, A. J.; Li, Y.; Wu, L.-J.

10.1101/2023.06.12.544691 — neuroscience — Posted on 2023-06-13

2667 Late-life Rapamycin Treatment Enhances Cardiomyocyte Relaxation Kinetics and Reduces Myocardial Stiffness

Chakraborty, A. D.; Kooiker, K.; Kobak, K. A.; Cheng, Y.; Lee, C. F.; Razumova, M.; Granzier, H.; Regnier, M.; Rabinovitch, P. S.; Moussavi-Harami, F.; Chiao, Y. A.

10.1101/2023.06.12.544619 — physiology — Posted on 2023-06-13

2668 High-Resolution Characterization of Human Brain Cortex with High-Fidelity Spatial Transcriptomic Slides (HiFi-Slides)

Xu, T.; Zhu, E.; Zhang, C.; Calandrelli, R.; Lin, P.; Zhong, S.

10.1101/2023.06.12.544625 — bioengineering — Posted on 2023-06-13

2669 In-situ metagenomics: A platform for rapid sequencing and analysis of metagenomes in less than one day

Tamames, J.; Jimenez, D.; Redondo, A.; Martinez-Garcia, S.; de los Rios, A.

10.1101/2023.01.25.525498 — genomics — Posted on 2023-06-13

2670 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

10.1101/2023.06.10.544434 — genomics — Posted on 2023-06-13

2671 Mitochondria- and ER-associated actin are required for mitochondrial fusion

Gatti, P.; Schiavon, C. R.; Manor, U.; Germain, M.

10.1101/2023.06.13.544768 — cell biology — Posted on 2023-06-13

2672 Dmo2p is required for Cox2p stability and plays a role in mitochondrial redox balance.

Soares, M. A.; Franco, L. V.; Chagas, J. A.; Gomes, F.; de Barros, M. H.

10.1101/2023.06.12.544600 — molecular biology — Posted on 2023-06-12

2673 Manipulating prior beliefs causally induces under- and overconfidence

Van Marcke, H.; Le Denmat, P.; Verguts, T.; Desender, K.

10.1101/2022.03.01.482511 — neuroscience — Posted on 2023-06-13

2674 Subtle introgression footprints at the end of the speciation continuum in a clade of Heliconius butterflies

Rougemont, Q.; Huber, B.; Martin, S. H.; Whibley, A.; Estrada, C.; Solano, D.; Orpet, R.; McMillan, W. O.; Frerot, B.; Joron, M.

10.1101/2022.12.19.520581 — evolutionary biology — Posted on 2023-06-13

2675 Ace and ace-like genes of invasive redlegged earth mite: Copy number variation, target-site mutations, and their associations with organophosphate insensitivity

Thia, J. A.; Umina, P. A.; Hoffmann, A. A.

10.1101/2022.11.02.514930 — evolutionary biology — Posted on 2023-06-13

2676 GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

Wang, L.; Hilander, T.; Liu, X.; Tsang, H.; Eriksson, O.; Jackson, C. B.; Varjosalo, M.; Zhao, H.

10.1101/2023.05.26.542385 — cell biology — Posted on 2023-06-13

2677 How formate dehydrogenase-lacking acetogen Clostridium bovifaecis utilize formate as the sole carbon source for its acetogenic growth?

Guan, Z. W.; Fu, B.; Conrad, R.; Qian, Q. Q.; Han, D.; Liu, B. H.; Liu, H.

10.1101/2023.06.12.544627 — microbiology — Posted on 2023-06-12

2678 Experimental evolution of Pseudomonas aeruginosa to colistin in spatially confined microdroplets identifies evolutionary trajectories consistent with adaptation in microaerobic lung environments

Disney-McKeethen, H. S.; Seo, S.; Mehta, H.; Ghosh, K.; Shamoo, Y.

10.1101/2023.06.12.544597 — microbiology — Posted on 2023-06-12

2679 Sodium channel endocytosis drives axon initial segment plasticity

FREAL, A.; Jamann, N.; Ten Bos, J.; Jansen, J.; Petersen, N.; Ligthart, T.; Hoogenraad, C.; Kole, M. H. P.

10.1101/2022.11.09.515770 — neuroscience — Posted on 2023-06-13

2680 BackWards - Unveiling the Brain's Topographic Organization of Paraspinal Sensory Input

Guekos, A.; Cole, D. M.; Doerig, M. A.; Staempfli, P.; Schibli, L.; Schuetz, P. A.; Schweinhardt, P.; Meier, M. L.

10.1101/2022.08.05.502912 — neuroscience — Posted on 2023-06-13

2681 Sensory prediction error drives subconscious motor learning outside of the laboratory

Albert, S. T.; Blaum, E.; Blustein, D.

10.1101/2023.02.22.529399 — neuroscience — Posted on 2023-06-13

2682 Combined direct/indirect detection allows identification of DNA termini in diverse sequencing datasets and supports a multiple-initiation-site model for HIV plus-strand synthesis

Wang, W.; Artiles, K. L.; Machida, S.; Benkirane, M.; Jain, N.; Fire, A.

10.1101/2023.06.12.544617 — genomics — Posted on 2023-06-13

2683 The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs

10.1101/2023.05.17.540811 — evolutionary biology — Posted on 2023-06-13

2684 Allele surfing causes maladaptation in a Pacific salmon of conservation concern

Rougemont, Q.; leroy, t.; Rondeau, E.; Koop, B. F.; Bernatchez, L.

10.1101/2022.11.10.515805 — evolutionary biology — Posted on 2023-06-13

2685 A nucleoid-associated protein is involved in the emergence of antibiotic resistance by promoting the frequent exchange of the replicative DNA polymerase in M. smegmatis

Ng, W. L.; Park, J. H.; Rego, E. H.

10.1101/2023.06.12.544663 — microbiology — Posted on 2023-06-12

2686 Competition for iron shapes metabolic antagonism between Bacillus subtilis and Pseudomonas

Lyng, M.; Jorgensen, J. P. B.; Schostag, M. D.; Jarmusch, S. A.; Aguilar, D. K. C.; Lozano-Andrade, C. N.; Kovacs, A. T.

10.1101/2023.06.12.544649 — microbiology — Posted on 2023-06-12

2687 Domestication signatures in the non-conventional yeast Lachancea cidri

Villarreal, P.; O'Donnell, S.; Agier, N.; Munoz-Guzman, F.; Benavides-Parra, J.; Urbina, K.; Pena, T. A.; Solomon, M.; Nespolo, R. F.; Fischer, G.; Varela, C.; Cubillos, F. A.

10.1101/2023.06.12.544598 — genetics — Posted on 2023-06-13

2688 Convergent Insulin and TGF-β signalling drives cancer cachexia by promoting aberrant fatbody ECM accumulation in a Drosophila tumour model

Bakopoulos, D.; Golenkina, S.; Dark, C.; Christie, L.; Sanchez-Sanchez, B.; Stramer, B.; Cheng, L.

10.1101/2023.06.10.544444 — developmental biology — Posted on 2023-06-13

2689 Enterovirus D68 capsid formation and stability requires acidic compartments

Galitska, G.; Jassey, A.; Wagner, M. A.; Pollack, N.; Jackson, W. T.

10.1101/2023.06.12.544695 — microbiology — Posted on 2023-06-13

2690 The Campylobacter concisus BisA protein plays a dual role: oxide-dependent anaerobic respiration and periplasmic methionine sulfoxide repair

Maier, R. J.; Benoit, S. L.

10.1101/2023.06.12.544688 — microbiology — Posted on 2023-06-13

2691 SaLSa: a combinatory approach of semi-automatic labeling and long short-term memory to classify behavioral syllables

Sakata, S.

10.1101/2023.04.05.535796 — neuroscience — Posted on 2023-06-13

2692 TKSM: Highly modular, user-customizable, and scalable transcriptomic sequencing long-read simulator

Karaoglanoglu, F.; Orabi, B.; Flannigan, R.; Chauve, C.; Hach, F.

10.1101/2023.06.12.544410 — bioinformatics — Posted on 2023-06-13

2693 A Mathematical Framework for Understanding Biological Recognition Systems

Brima, Y.

10.1101/2023.06.08.544240 — animal behavior and cognition — Posted on 2023-06-13

2694 CREATION AND CHARACTERIZATION OF A RECOMBINANT MAMMALIAN ORTHOREOVIRUS EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 PEPTIDES

Jandick, N. A.; Miller, C. L.

10.1101/2023.06.12.544655 — microbiology — Posted on 2023-06-13

2695 Isolation of a Chlamydia Strain from Lung Tissue Samples in Healthy Chickens Exhibiting Antagonistic Effects on Avian Infectious Bronchitis Virus

Zhen, M.

10.1101/2023.05.10.540153 — microbiology — Posted on 2023-06-13

2696 KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

Kauwe, G.; Pareja-Navarro, K.; Yao, L.; Chen, J.; Wong, I.; Saloner, R.; Cifuentes, H.; Nana, A. L.; Shah, S.; Li, Y.; Le, D.; Spina, S.; Grinberg, L. T.; Seeley, W. W.; Kramer, J.; Sacktor, T.; Schilling, B.; Gan, L.; Casaletto, K. B.; Tracy, T. E.

10.1101/2023.06.12.543777 — neuroscience — Posted on 2023-06-13

2697 Methodological considerations for behavioral studies relying on response time outcomes through online crowdsourcing platforms

McConnell, P. A.; Finetto, C.; Heise, K.-F.

10.1101/2023.06.12.544611 — scientific communication and education — Posted on 2023-06-13

2698 GENA-LM: A Family of Open-Source Foundational Models for Long DNA Sequences

Fishman, V.; Kuratov, Y.; Petrov, M.; Shmelev, A.; Shepelin, D.; Chekanov, N.; Kardymon, O.; Burtsev, M.

10.1101/2023.06.12.544594 — bioinformatics — Posted on 2023-06-13

2699 cudaMMC - GPU-enhanced Multiscale Monte Carlo Chromatin 3D Modelling

Wlasnowolski, M.; Grabowski, P.; Roszczyk, D.; Kaczmarski, K.; Plewczynski, D.

10.1101/2023.06.12.544609 — bioinformatics — Posted on 2023-06-13

2700 Investigating mitochondrial gene expression patterns in Drosophila melanogaster using network analysis to understand aging mechanisms

Mangoni, M.; Petrizzelli, F.; Liorni, N.; Bianco, S. D.; Biagini, T.; Napoli, A.; Adinolfi, M.; Guzzi, P. H.; Novelli, A.; Caputo, V.; Mazza, T.

10.1101/2023.05.16.540914 — bioinformatics — Posted on 2023-06-13

2701 Identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes, supported by short- and long-read transcriptome data

Jutersek, M.; Gerasymenko, I. M.; Petek, M.; Haumann, E.; Vacas Gonzalez, S.; Kallam, K.; Gianoglio, S.; Navarro-Llopis, V.; Navarro Fuertes, I.; Patron, N.; Orzaez, D.; Gruden, K.; Warzecha, H.; Baebler, S.

10.1101/2023.06.09.544309 — biochemistry — Posted on 2023-06-13

2702 Construction of a multi-tissue cell atlas reveals cell-type-specific regulation of molecular and complex phenotypes in pigs

Chen, L.; Li, H.; Teng, J.; Wang, Z.; Qu, X.; Chen, Z.; Cai, X.; Zeng, H.; Bai, Z.; Li, J.; Pan, X.; Yan, L.; Wang, F.; Lin, L.; Luo, Y.; Sahana, G.; Lund, M.; Ballester, M.; Crespo-Piazuelo, D.; Karlskov-Mortensen, P.; Fredholm, M.; Clop, A.; Amills, M.; Loving, C.; Tuggle, C.; Madsen, O.; Li, J.; Zhang, Z.; Liu, G.; Jiang, J.; Fang, L.; Yi, G.

10.1101/2023.06.12.544530 — genetics — Posted on 2023-06-13

2703 Gene regulatory programs in the life history of Salpingoeca rosetta

Fumagalli, M. R.; Zapperi, S.; La Porta, C. A. M.

10.1101/2023.06.12.544615 — evolutionary biology — Posted on 2023-06-13

2704 In vitro modelling of anterior primitive streak patterning with hESC reveals the dynamic of WNT and NODAL signalling required to specify notochord progenitors

Garcia, M. R.; Thimonier, C.; Angoura, K.; Ozga, E.; MacPherson, H.; Blin, G.

10.1101/2023.06.01.543323 — developmental biology — Posted on 2023-06-13

2705 On the origin of F-wave: involvement of central synaptic mechanisms

Ozyurt, M. G.; Nascimento, F.; Brownstone, R. M.; Beato, M.

10.1101/2023.06.12.544675 — neuroscience — Posted on 2023-06-13

2706 Multivariate classification of multichannel long-term electrophysiology data identifies different sleep stages in fruit flies

Jagannathan, S. R.; Jeans, R.; Van De Poll, M. N.; van Swinderen, B.

10.1101/2023.06.12.544704 — neuroscience — Posted on 2023-06-13

2707 Spatial proteomics reveals heterogeneity in neural markers underpinning high-fat diet-induced myopathy in male mice.

Hardowar, L.; Vadakekolathu, J.; Rutella, S.; Hulse, R.; Doig, C. L.

10.1101/2023.06.12.544330 — physiology — Posted on 2023-06-13

2708 Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.

Correia, J. C.; Jannig, P. R.; Gosztyla, M. L.; Cervenka, I.; Ducommun, S.; Praestholm, S. M.; Dumont, K. D.; Liu, Z.; Liang, Q.; Edsgard, D.; Emanuelsson, O.; Gregorevic, P.; Westerblad, H.; Venckunas, T.; Brazaitis, M.; Kamandulis, S.; Lanner, J. T.; Yeo, G. W.; Ruas, J. L.

10.1101/2023.06.12.544338 — physiology — Posted on 2023-06-13

2709 Performance analysis of conventional and AI-based variant callers using short and long reads

Abdelwahab, O.; Belzile, F.; Torkamaneh, D.

10.1101/2023.06.12.544612 — bioinformatics — Posted on 2023-06-13

2710 GDmicro: classifying host disease status with GCN and Deep adaptation network based on the human gut microbiome data

Liao, H.; Shang, J.; Sun, Y.

10.1101/2023.06.12.544696 — bioinformatics — Posted on 2023-06-13

2711 The effect of parental age on the quantity and quality of offspring in Syngnathus typhle, a species with male pregnancy.

Pappert, F. A.; Kolbe, D.; Dubin, A.; Roth, O.

10.1101/2023.06.12.544574 — evolutionary biology — Posted on 2023-06-13

2712 The influence of social lifestyles on host-microbe symbioses in the bees

Mee, L.; Barribeau, S. M.

10.1101/2023.06.12.544601 — evolutionary biology — Posted on 2023-06-13

2713 BERTrand - peptide:TCR binding prediction using Bidirectional Encoder Representations from Transformers augmented with random TCR pairing

Myronov, A.; Mazzocco, G.; Krol, P.; Plewczynski, D.

10.1101/2023.06.12.544613 — immunology — Posted on 2023-06-13

2714 Improved short-channel regression for mapping resting-state functional connectivity networks using functional near-infrared spectroscopy

Novi Junior, S. L.; Abdalmalak, A.; Kazazian, K.; Norton, L.; Debicki, D.; Mesquita, R.; Owen, A. M.

10.1101/2023.06.12.543244 — neuroscience — Posted on 2023-06-13

2715 Active perceptual learning involves motor exploration and adaptation of predictive sensory integration

Hirano, M.; Furuya, S.

10.1101/2022.02.17.480969 — neuroscience — Posted on 2023-06-13

Hu, M.; Zhang, Y.; Yuan, Y.; Ma, W.; Zheng, Y.; Gu, Q.; Xie, X. S.

10.1101/2022.12.18.520903 — systems biology — Posted on 2023-06-13

2717 MRBEE: A novel bias-corrected multivariable Mendelian Randomization method

Lorincz-Comi, N. J.; Yang, Y.; Li, G.; Zhu, X.

10.1101/2023.01.10.523480 — genomics — Posted on 2023-06-12

2718 A reference single-cell map of freshly dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective synovial biopsy collection

Edalat, S. G.; Gerber, R.; Houtman, M.; Kuret, T.; Izanc, N.; Micheroli, R.; Buerki, K.; Burja, B.; Pauli, C.; Rotar, Z.; Tomsic, M.; Cucnik, S.; Distler, O.; Ospelt, C.; Sodin Semrl, S.; Robinson, M. D.; Frank Bertoncelj, M.

10.1101/2022.06.01.493823 — genomics — Posted on 2023-06-12

2719 Rapid molecular species identification of mammalian scat samples using nanopore adaptive sampling

Frank, L. E.; Lindsey, L. L.; Kipp, E. J.; Faulk, C.; Stone, S.; Roerick, T. M.; Moore, S. A.; Wolf, T. M.; Larsen, P. A.

10.1101/2023.06.12.544605 — genomics — Posted on 2023-06-12

2720 GpsB control of PASTA kinase activity in Listeria monocytogenes influences peptidoglycan synthesis during cell wall stress and cytosolic survival

Kelliher, J. L.; Daanen, M. E.; Sauer, J.-D.

10.1101/2023.06.12.544644 — microbiology — Posted on 2023-06-12

2721 Non-differentiable activity in the brain

Tsubo, Y.; Shinomoto, S.

10.1101/2023.06.12.544700 — neuroscience — Posted on 2023-06-12

2722 Semi-automated curation and manual addition of sequences to build reliable and extensive reference databases for ITS2 vascular plant DNA (meta-)barcoding

Quaresma, A.; Garcia, C. A. Y.; Rufino, J.; Honrado, M.; Amaral, J.; Brodschneider, R.; Brusbardis, V.; Gratzer, K.; Hatjina, F.; Kilpinen, O.; Pietropaoli, M.; Roessink, I.; van der Steen, J.; Vejsnaes, F.; Pinto, M. A.; Keller, A.

10.1101/2023.06.12.544582 — bioinformatics — Posted on 2023-06-13

2723 takeout gene expression is associated with temporal kin recognition

Potticary, A.; McKinney, E. C.; Moore, P. J.; Moore, A. J.

10.1101/2023.06.12.544599 — animal behavior and cognition — Posted on 2023-06-12

2724 In situ spatial reconstruction of distinct normal and pathological cell populations within the human adrenal gland

Fu, R.; Walters, K.; Koc, K.; Baldwin, A.; Clay, M.; Kiseljak-Vassiliades, K.; Fishbein, L.; Mukherjee, N.

10.1101/2023.06.12.544676 — genomics — Posted on 2023-06-12

2725 A hybrid RNA FISH immunofluorescence protocol on Drosophila polytene chromosomes

Gilbonio, H. E.; Puckett, G. L.; Nguyen, E.; Rieder, L. E.

10.1101/2023.06.12.544616 — genetics — Posted on 2023-06-12

2726 Co-aggregation and parallel aggregation of specific proteins in major mental illness

Samardzija, B.; Jukovic, M.; Zaharija, B.; Renner, E.; Palkovits, M.; Bradshaw, N. J.

10.1101/2023.06.12.544321 — neuroscience — Posted on 2023-06-12

2727 Cognitive Dynamics Estimation: A whole-brain spatial regression paradigm for extracting the temporal dynamics of cognitive processes

Koyama, Y.; Yamamoto, T.; Hirayama, J.-i.; Jimura, K.; Sadato, N.; Chikazoe, J.

10.1101/2023.06.12.543130 — neuroscience — Posted on 2023-06-12

2728 Computing Multiple Sequence Alignments given a Constraint Subset Alignment using EMMA

Shen, C.; Liu, B.; Williams, K. P.; Warnow, T.

10.1101/2023.06.12.544642 — bioinformatics — Posted on 2023-06-12

2729 Incomplete Reprogramming of DNA Replication Timing in Induced Pluripotent Stem Cells

Edwards, M. M.; Wang, N.; Massey, D.; Egli, D.; Koren, A.

10.1101/2023.06.12.544654 — genetics — Posted on 2023-06-12

2730 Precise traits from sloppy components: perception and the origin of phenotypic response

Frank, S. A.

10.1101/2022.12.27.522001 — evolutionary biology — Posted on 2023-06-12

2731 Understanding the Divergent Evolution and Epidemiology of H3N8 Influenza Viruses in Dogs and Horses

Wasik, B. R.; Rothschild, E.; Voorhees, I. E.; Reedy, S. E.; Murcia, P. R.; Pusterla, N.; Chambers, T. M.; Goodman, L. B.; Kile, J. C.; Holmes, E. C.; Parrish, C. R.

10.1101/2023.03.22.533763 — evolutionary biology — Posted on 2023-06-12

2732 Dosage-sensitivity shapes how genes transcriptionally respond to allopolyploidy and homoeologous exchange in resynthesized Brassica napus

Bird, K. A.; Pires, J. C.; VanBuren, R.; Xiong, Z.; Edger, P. P.

10.1101/2021.11.16.468838 — evolutionary biology — Posted on 2023-06-12

2733 Dependent variable selection in phylogenetic generalized least squares regression analysis under Pagel's lambda model

Chen, Z.-L.; Guo, H.-J.; Niu, D.-K.

10.1101/2023.05.21.541623 — evolutionary biology — Posted on 2023-06-12

2734 The fitness consequences of wildlife conservation translocations: a meta-analysis

Gross, I. P.; Wilson, A. E.; Wolak, M. E.

10.1101/2023.01.14.524021 — ecology — Posted on 2023-06-12

2735 Natural thermal stress-hardening of corals through cold temperature pulses in the Thai Andaman Sea

Wall, M.; Doering, T.; Pohl, N.; Putchim, L.; Ratanawongwan, T.; Roik, A.

10.1101/2023.06.12.544549 — ecology — Posted on 2023-06-12

2736 Fear and foraging opportunities interact with temperature and seasonality to drive diversity in fish life histories

Kindsvater, H. K.; Juan Jorda, M. J.; Dulvy, N. K.; Horswill, C.; Matthiopoulos, J.; Mangel, M.

10.1101/2022.08.20.504655 — ecology — Posted on 2023-06-12

2737 Contrasting responses to aridity by different-sized decomposers cause similar decomposition rates across a precipitation gradient

Torsekar, V. R.; Sagi, N.; Johnson, A. D.; Hawlena, Y.; Gavish-Regev, E.; Hawlena, D.

10.1101/2023.06.04.541603 — ecology — Posted on 2023-06-12

2738 Antero-posterior gradients of cell plasticity and proliferation modulate posterior regeneration in the annelid Platynereis

Bideau, L.; Baduel, L.; Basso, M.; Gilardi-Hebenstreit, P.; Ribes, V.; Vervoort, M.; Gazave, E.

10.1101/2023.06.12.544593 — developmental biology — Posted on 2023-06-12

2739 Ablation of Max expression induces meiotic onset in sexually undifferentiated germ cells

Suzuki, A.; Uranishi, K.; Nishimoto, M.; Mizuno, Y.; Mizuno, S.; Takahashi, S.; Eisenman, R. N.; Okuda, A.

10.1101/2023.06.10.544477 — developmental biology — Posted on 2023-06-12

2740 Gut-associated microbes are present and active in the pig nasal cavity

Obregon-Gutierrez, P.; Bonillo-Lopez, L.; Correa-Fiz, F.; Sibila, M.; Segales, J.; Kochanowski, K.; Aragon, V.

10.1101/2023.06.12.544581 — microbiology — Posted on 2023-06-12

2741 Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2

Shaker, M. R.; Slonchak, A.; Al-mhanawi, B.; Morrison, S. D.; Sng, J. D. J.; Cooper-White, J. J.; Khromykh, A. A.; Wolvetang, E. J.

10.1101/2023.06.12.544552 — neuroscience — Posted on 2023-06-12

2742 How total mRNA influences cell growth

Calabrese, L.; Ciandrini, L.; Cosentino Lagomarsino, M.

10.1101/2023.03.17.533181 — systems biology — Posted on 2023-06-12

2743 Modeling Protein Structure Using Geometric Vector Field Networks

Mao, W.; Zhu, M.; Chen, H.; Shen, C.

10.1101/2023.05.07.539736 — systems biology — Posted on 2023-06-12

2744 Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

Masson, S. W.; Madsen, S.; Cooke, K. C.; Potter, M.; Vegas, A. D.; Carroll, L.; Thillainadesan, S.; Cutler, H. B.; Walder, K. R.; Cooney, G. J.; Morahan, G.; Stöckli, J.; James, D. E.

10.1101/2023.03.01.530673 — systems biology — Posted on 2023-06-12

2745 Partitioned Local Depth analysis of time course transcriptomic data reveals elaborate community structure

Khoury, M.; Berenhaut, K.; Moore, K.; Allen, E.; Harkey, A.; Muhlemann, J. K.; Craven, C.; Xu, J.; Jain, S.; John, D.; Norris, J.; Muday, G. K.

10.1101/2022.07.25.501352 — systems biology — Posted on 2023-06-12

2746 Improving modelling for epidemic responses: reflections from members of the UK infectious disease modelling community on their experiences during the COVID-19 pandemic

Sherratt, K.; Carnegie, A. C.; Kucharski, A.; Cori, A.; Pearson, C. A.; Jarvis, C. I.; Overton, C.; Weston, D.; Hill, E. M.; Knock, E.; Fearon, E.; Nightingale, E.; Hellewell, J.; Edmunds, W. J.; Arenas, J. V.; Prem, K.; Pi, L.; Baguelin, M.; Kendall, M.; Ferguson, N.; Davies, N.; Eggo, R. M.; van Elsland, S.; Russell, T.; Funk, S.; Liu, Y.; Abbott, S.

10.1101/2023.06.12.544667 — scientific communication and education — Posted on 2023-06-12

2747 NBR1 -mediated selective autophagy of ARF7 modulates root branching

Ebstrup, E.; Ansboel, J.; Chevalier, J.; Clemmens, P.; Rodriguez, E.

10.1101/2022.08.19.504407 — plant biology — Posted on 2023-06-12

2748 Dynamical modelling of proliferative-invasive plasticity and IFN-gamma signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity

Subhadarshini, S.; Sahoo, S.; Debnath, S.; Somarelli, J.; Jolly, M. K.

10.1101/2023.01.09.523355 — cancer biology — Posted on 2023-06-12

2749 Characterisation of Plasmodium vivax lactate dehydrogenase dynamics in P. vivax infections

Cao, P.; Kho, S.; Grigg, M. J.; Barber, B. E.; Piera, K. A.; William, T.; Poespoprodjo, J. R.; Jang, I. K.; Simpson, J. A.; McCaw, J.; Anstey, N. M.; McCarthy, J. S.; Britton, S.

10.1101/2023.06.12.544683 — biophysics — Posted on 2023-06-12

2750 Quantifying Intratumor Heterogeneity by Key Genes Selected Using Concrete Autoencoder

Tanvir, R. B.; Sobhan, M.; Mamun, A. A.; Mondal, A. M.

10.1101/2021.09.06.459161 — bioinformatics — Posted on 2023-06-12

2751 Cyclic mechanical stretching stimuli promotes angiocrine signals during in vitro liver bud formation from human pluripotent stem cells

Yoshimoto, K.; Maki, K.; Adachi, T.; Kamei, K.-i.

10.1101/2023.06.11.544492 — bioengineering — Posted on 2023-06-12

2752 Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function

Chang, C.; Banerjee, S. L.; Park, S. S.; Zhang, X.; Cotnoir-White, D.; Desbois, M.; Grill, B.; Kania, A.

10.1101/2023.06.12.544638 — cell biology — Posted on 2023-06-12

2753 Tetraspanins from Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production.

Ruangsuwast, A.; Smout, M. J.; Brindley, P. J.; Loukas, A.; Laha, T.; Chaiyadet, S.

10.1101/2023.06.12.544604 — cell biology — Posted on 2023-06-12

2754 Self-supervised denoising for structured illumination microscopy enables long-term super-resolution live-cell imaging

Chen, X.; Qiao, C.; Jiang, T.; Liu, J.; Meng, Q.; Zeng, Y.; Chen, H.; Qiao, H.; Li, D.; Wu, J.

10.1101/2023.04.05.535684 — cell biology — Posted on 2023-06-12

2755 Altitude-dependent agro-ecologies impact the microbiome diversity of scavenging indigenous chicken in Ethiopia

Glendinning, L.; Jia, X.; Kebede, A.; Oyola, S. O.; Park, J.-E.; Park, W.; Assiri, A.; Holm, J. B.; Kristiansen, K.; Han, J.; Hanotte, O.

10.1101/2023.06.12.544316 — microbiology — Posted on 2023-06-12

2756 Decoding Root Biogeography: Building Reduced Complexity Functional Rhizosphere Microbial Consortia

Chen, M.; Acharya, S.; Yee, M. O.; Kabugao, K. G.; Chakraborty, R.

10.1101/2023.06.12.544662 — microbiology — Posted on 2023-06-12

2757 Parallel genetic adaptation of Bacillus subtilis to different plant species

Hu, G.; Wang, Y.; Blake, C.; Nordgaard, M.; Liu, X.; Wang, B.; Kovacs, A. T.

10.1101/2023.03.17.533125 — microbiology — Posted on 2023-06-12

2758 Generative models inferred using statistical tests reveal context-dependent syllable transitions in Bengalese finch songs

Lu, J.; Surendralal, S.; Bouchard, K. E.; Jin, D. Z.

10.1101/2022.11.15.516592 — neuroscience — Posted on 2023-06-12

2759 Overcoming Limitations: Deep Neural Network Models Show Promise in Reducing Multi-Talker Noise Interference for Cochlear Implant Listeners

Borjigin, A.; Kokkinakis, K.; Bharadwaj, H. M.; Stohl, J. S.

10.1101/2022.08.25.504678 — neuroscience — Posted on 2023-06-12

2760 Cytoplasmic Male Sterility and Abortive Seed Traits Generated through Mitochondrial Genome Editing Coupled with Allotopic Expression of atp1 in Tobacco

Dewey, R. E.; Selote, D.; Griffin, H. C.; Dickey, A. N.; Jantz, D.; Smith, J. J.; Matthiadis, A.; Strable, J.; Kestell, C.; Smith, W. A.

10.1101/2023.06.12.544621 — plant biology — Posted on 2023-06-12

2761 TP53-dependent CRISPR-Cas9 sex bias across cancer types affects MYC, PIK3CA, and SUV39H1 mediated by factors including SOX9, FOXO4, and PRC1

Guo, M.; Xiong, Y.

10.1101/2022.08.03.502574 — cancer biology — Posted on 2023-06-12

2762 cProSite: A web based interactive platform for online proteomics, phosphoproteomics, and genomics data analysis

Wang, D.; Qian, X.; Du, Y.-C. N.; Sanchez-Solana, B.; Chen, K.; Kanigicherla, M.; Jenkins, L. M.; Luo, J.; Eng, S.; Brian, P.; Chen, B.; Yao, X.; Nguyen, T.; Tripathi, B. K.; Durkin, M. R.; Lowy, D. R.

10.1101/2023.06.10.543932 — bioinformatics — Posted on 2023-06-12

2763 Alteration of actin cytoskeletal organisation in fetal akinesia deformation sequence

Juhlen, R.; Martinelli, V.; Rencurel, C.; Fahrenkrog, B.

10.1101/2023.06.12.544620 — cell biology — Posted on 2023-06-12

2764 Phosphatases modified by LH signaling in rat ovarian follicles and their role in regulating the NPR2 guanylyl cyclase

Egbert, J. R.; Silbern, I.; Uliasz, T. F.; Lowther, K. M.; Yee, S.-P.; Urlaub, H.; Jaffe, L. A.

10.1101/2023.06.12.544636 — cell biology — Posted on 2023-06-12

2765 Sustained growth and rapid dispersal of chitin-associated marine bacteria

Guessous, G.; Patsalo, V.; Balakrishnan, R.; Caglar, T.; Williamson, J.; Hwa, T.

10.1101/2023.06.12.544524 — microbiology — Posted on 2023-06-12

2766 RBD-based high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways

Gagne, M.; Flynn, B. J.; Honeycutt, C. C.; Flebbe, D. R.; Andrew, S. F.; Provost, S. J.; McCormick, L.; Van Ry, A.; McCarthy, E.; Todd, J.-P. M.; Bao, S.; Teng, I.-T.; Marciano, S.; Rudich, Y.; Li, C.; Pessaint, L.; Dodson, A.; Cook, A.; Lewis, M. G.; Andersen, H.; Zahradnik, J.; Nason, M. C.; Foulds, K. E.; Kwong, P. D.; Roederer, M.; Schreiber, G.; Seder, R. A.; Douek, D. C.

10.1101/2023.06.09.544432 — immunology — Posted on 2023-06-12

2767 Interaction of an alpha-synuclein epitope with HLA-DRB1*15:01 triggers enteric features in mice reminiscent of prodromal Parkinson's disease

Garretti, F.; Monahan, C.; Sloan, N.; Bergen, J.; Shariar, S.; Kim, S. W.; Sette, A.; Cutforth, T.; Kanter, E.; Sulzer, D.; Agalliu, D.

10.1101/2022.02.03.479014 — neuroscience — Posted on 2023-06-12

2768 Brain Structure and Working Memory Adaptations Associated with Maturation and Aging in Mice

Clifford, K. P.; Miles, A.; Prevot, T. D.; Misquitta, K. A.; Ellegood, J.; Lerch, J. P.; Sibille, E.; Nikolova, Y. S.; Banasr, M.

10.1101/2023.02.24.529940 — neuroscience — Posted on 2023-06-12

2769 Bilateral Human Laryngeal Motor Cortex in Perceptual Decision of Lexical Tone and Voicing of Consonant

Liang, B.; Li, Y.; Zhao, W.; Du, Y.

10.1101/2022.04.12.487725 — neuroscience — Posted on 2023-06-12

2770 Alternative splicing of a potato disease resistance gene maintains homeostasis between development and immunity, and functions as a novel process for pathogen surveillance

Sun, B.; Huang, J.; Gao, C.; Li, K.; Zhao, F.; Kong, L.; Wang, L.; Shen, J.; Wang, Y.; Halterman, D.; Dong, S.

10.1101/2023.06.09.544375 — plant biology — Posted on 2023-06-12

2771 Cryo-EM structures of a synthetic antibody against 22 kDa claudin-4 reveal its complex with Clostridium perfringens enterotoxin

Erramilli, S. K.; Dominik, P. K.; Ogbu, C. P.; Kossiakoff, A. A.; Vecchio, A. J.

10.1101/2023.06.12.544689 — biophysics — Posted on 2023-06-12

2772 Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB

Acharya, A.; Bret, H.; Huang, J.-W.; Muetze, M.; Goese, M.; Kissling, V.; Seidel, R.; Ciccia, A.; Guerois, R.; Cejka, P.

10.1101/2023.06.12.544631 — biochemistry — Posted on 2023-06-12

2773 Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis

Toullec, G.; Radecker, N.; Pogoreutz, C.; Banc Prandi, G.; Escrig, S.; Genoud, C.; Martin Olmos, C.; Spangenberg, J.; Meibom, A.

10.1101/2023.06.12.544603 — ecology — Posted on 2023-06-12

2774 Sorafenib inhibits invasion of multicellular organoids that mimic Lymphangioleiomyomatosis nodules.

Koc-Gunel, S.; Gautam, L. K.; Calvert, B. A.; Murthy, S.; Harriott, N. C.; Nawroth, J. C.; Zhou, B.; Krymskaya, V. P.; Ryan, A. L.

10.1101/2023.06.12.544372 — cell biology — Posted on 2023-06-12

2775 Shotgun metagenomic analysis of the skin mucus bacteriome of the common carp (Cyprinus carpio)

Papp, M.; Toth, A. G.; Nagy, S. A.; Erdelyi, K.; Maroti, G.; Cox, N.; Czikk, L.; Katics, M.; Bekesi, L.; Solymosi, N.

10.1101/2023.06.12.544578 — microbiology — Posted on 2023-06-12

2776 SAD-1 kinase controls presynaptic phase separation by relieving SYD-2/Liprin-α autoinhibition

McDonald, N. A.; Tao, L.; Dong, M.-Q.; Shen, K.

10.1101/2023.06.12.544643 — neuroscience — Posted on 2023-06-12

2777 Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids

Olsen, C.; Wang, C.; Aizenshtadt, A.; Abadpour, S.; Lundanes, E.; Skottvoll, F. S.; Golovin, A.; Busek, M.; Krauss, S.; Scholz, H.; Wilson, S. R.

10.1101/2023.06.12.544566 — biochemistry — Posted on 2023-06-12

2778 De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

Roy, A.; Shi, L.; Chang, A.; Dong, X.; Fernandez, A.; Kraft, J. C.; Li, J.; Le, V. Q.; Winegar, R. V.; Cherf, G. M.; Slocum, D.; Poulson, P. D.; casper, G. E.; Vallecillo-Zuniga, M. L.; Valdoz, J. C.; Miranda, M. C.; Bai, H.; Kipnis, Y.; Olshefsky, A.; Priya, T.; Carter, L.; Ravichandran, R.; Chow, C.; Johnson, M. R.; Chang, S.; Roy, A.; Overed-Sayer, C.; Finch, D. K.; Lowe, D.; Bera, A. K.; Matute-Bello, G.; Birkland, T. P.; DiMaio, F.; Raghu, G.; Cochran, J. R.; Stewart, L.; Campbell, M. G.; Van Ry, P. M.; Springer, T. A.; Baker, D.

10.1101/2023.06.12.544624 — biochemistry — Posted on 2023-06-12

2779 Combination EZH2 inhibition and retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

OBrien, E.; Tse, C.; Tracy, I.; Reddin, I.; Selfe, J.; Gibson, J.; Tapper, W.; Pengelly, R. J.; Gao, J.; Aladowicz, E.; Petts, G.; Thway, K.; Popov, S.; Kelsey, A.; Underwood, T. J.; Shipley, J.; Walters, Z. S.

10.1101/2023.06.12.544568 — cancer biology — Posted on 2023-06-12

2780 ModularImageAnalysis (MIA): Assembly of modularised image and object analysis workflows in ImageJ

Cross, S. J.; Fisher, J. D. J. R.; Jepson, M. A.

10.1101/2023.06.12.544614 — bioinformatics — Posted on 2023-06-12

2781 The SOCE system is critical for membrane bleb formation to drive avian primordial germ cell migration

Morita, M.; Morimoto, M.; Teramoto, T.; Ikenouchi, J.; Atsuta, Y.; Saito, D.

10.1101/2023.06.12.544577 — developmental biology — Posted on 2023-06-12

2782 Identification of signalling pathways involved in gill regeneration in zebrafish

Cadiz, L.; Reed, M.; Monis, S.; Akimenko, M.-A.; Jonz, M. G.

10.1101/2023.06.12.544629 — developmental biology — Posted on 2023-06-12

2783 Multifaceted roles of SAMHD1 in cancer

McLaughlin, K.-M.; Cinatl, J.; Wass, M. N.; Michaelis, M.

10.1101/2021.07.03.451003 — cancer biology — Posted on 2023-06-12

2784 Filament structure and subcellular organization of the bacterial intermediate filament-like protein crescentin

Liu, Y.; van den Ent, F.; Löwe, J.

10.1101/2023.06.04.543601 — microbiology — Posted on 2023-06-12

2785 All-optical interrogation of brain-wide activity in freely swimming larval zebrafish

Chai, Y.; Qi, K.; Wu, Y.; Li, D.; Tan, G.; Guo, Y.; Chu, J.; Mu, Y.; Shen, C.; Wen, Q.

10.1101/2023.05.24.542114 — neuroscience — Posted on 2023-06-12

2786 Distinct subtypes of grey matter heterotopia show subtype-specific morpho-electric neuronal properties and dynamics of epileptiform activity in mice

Vermoyal, J.-C.; Hardy, D.; Goirand-Lopez, L.; Vinck, A.; Silvagnoli, L.; Fortoul, A.; Francis, F.; Cappello, S.; Bureau, I.; Represa, A.; Cardoso, C.; Watrin, F.; Marissal, T.; Manent, J.-B.

10.1101/2023.06.06.543853 — neuroscience — Posted on 2023-06-12

2787 Sensitivity to direction and velocity of fast frequency chirps in the inferior colliculus of awake rabbit

Mitchell, P. W.; Henry, K. S.; Carney, L. H.

10.1101/2022.10.26.513923 — neuroscience — Posted on 2023-06-12

2788 Towards a Neurometric-based Construct Validity of Trust

Chen, P.-H. A.; Fareri, D.; Guroglu, B.; Delgado, M. R.; Chang, L. J.

10.1101/2021.07.04.451074 — neuroscience — Posted on 2023-06-12

2789 A new species of Lethrinops (Cichliformes: Cichlidae) from a Lake Malawi satellite lake, believed to be extinct in the wild.

Turner, G. F.; Crampton, D. A.; Genner, M. J.

10.1101/2023.03.17.533142 — zoology — Posted on 2023-06-12

2790 Native Mass Spectrometry of Complexes Formed by Molecular Glues Reveals Stoichiometric Rearrangement of E3 Ligases

Jackson, C.; Beveridge, R.

10.1101/2023.02.03.526954 — biochemistry — Posted on 2023-06-12

2791 The oxygen-induced thiosulfate production during Sulfate reduction, Autotrophic denitrification, Nitrification and Anammox (SANIA) integrated process towards next-generation mainstream wastewater treatment

Jiang, C.-k.; Deng, Y.-F.; Chen, G.-H.; Wu, D.

10.1101/2023.06.12.544556 — microbiology — Posted on 2023-06-12

2792 Genetic and immune determinants of E. coli liver abscess formation

Hullahalli, K.; Dailey, K. G.; Hasegawa, Y.; Suzuki, M.; Zhang, H.; Threadgill, D. W.; Waldor, M. K.

10.1101/2023.06.11.543319 — microbiology — Posted on 2023-06-12

2793 Comparative proteomic analysis of the hemolymph and salivary glands of Rhodnius prolixus and R. colombiensis reveals candidates associated with differential lytic activity against Trypanosoma cruzi I and T. cruzi II

Barbosa, H.; Quevedo, Y. S.; Torres, A. M.; Veloza, G. A. G.; Carranza Martinez, J. C.; Urrea-Montes, D. A.; Robello-Porto, C.; Vallejo, G. A.

10.1101/2023.06.12.544535 — microbiology — Posted on 2023-06-12

2794 Interleukin-27-induced HIV-resistant dendritic cells suppress reveres transcription following virus entry in an SPTBN1, Autophagy, and YB-1 independent manner

Imamichi, T.; Chen, Q.; Sowrirajan, B.; Yang, J.; Laverdure, S.; Mele, A. R.; Watkins, C.; Adelsberger, J. W.; Higgins, J.; Sui, H.

10.1101/2023.06.12.544550 — immunology — Posted on 2023-06-12

2795 Assembly of 43 diverse human Y chromosomes reveals extensive complexity and variation

Hallast, P.; Ebert, P.; Loftus, M.; Yilmaz, F.; Audano, P. A.; Logsdon, G. A.; Bonder, M. J.; Zhou, W.; Hoeps, W.; Kim, K.; Li, C.; Hoyt, S. J.; Dishuck, P. C.; Porubsky, D.; Tsetsos, F.; Kwon, J. Y.; Zhu, Q.; Munson, K. M.; Hasenfeld, P.; Harvey, W. T.; Lewis, A. P.; Kordosky, J.; Hoekzema, K.; (HGSVC), T. H. G. S. V. C.; O'Neill, R. J.; Korbel, J. O.; Tyler-Smith, C.; Eichler, E. E.; Shi, X.; Beck, C. R.; Marschall, T.; Konkel, M. K.; Lee, C.

10.1101/2022.12.01.518658 — genomics — Posted on 2023-06-12

2796 Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation

van den Bosch, A.; van der Poel, M.; Fransen, N.; Vincenten, M.; Bobeldijk, A.; Jongejan, A.; Engelenburg, H.; Moerland, P.; Smolders, J.; Huitinga, I.; Hamann, J.

10.1101/2023.06.11.544204 — neuroscience — Posted on 2023-06-12

2797 Impaired motor-to-sensory transformation mediates auditory hallucinations

Yang, F.; Zhu, H.; Fang, X.; Yu, L.; Wu, Z.; Li, S.; Zhang, C.; Tian, X.

10.1101/2023.06.10.544451 — neuroscience — Posted on 2023-06-12

2798 Minimum entropy framework identifies a novel class of genomic functional elements and reveals regulatory mechanisms at human disease loci

Betti, M. J.; Aldrich, M.; Gamazon, E. R.

10.1101/2023.06.11.544507 — genomics — Posted on 2023-06-12

2799 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

10.1101/2023.06.10.544434 — genomics — Posted on 2023-06-12

2800 Effect of Dual Leucine Zipper Kinase Inhibitor GNE-3511 on Epileptogenesis and Cognitive and Behavioral Changes in a Temporal Lobe Epilepsy Model in Mice

Acar, D.; Tunccan, E.; Selek, S. N.; Sayin, I. E.; Asaroglu, C. B.; Tumentemur, G.; Arslan, D. O.; Ozdemir, S.; Suyen, G. G.

10.1101/2023.06.11.544443 — neuroscience — Posted on 2023-06-12

2801 cTBS Over the Left Supplementary Motor Area (lSMA) Does Not Modulate Rhythmic Bimanual Coordination in the Presence and Absence of Visual Cues

Kaur, J.; Balasubramaniam, R.

10.1101/2023.06.10.544481 — neuroscience — Posted on 2023-06-12

2802 Repository of logically consistent real-world Boolean network models

Pastva, S.; Safranek, D.; Benes, N.; Brim, L.; Henzinger, T.

10.1101/2023.06.12.544361 — systems biology — Posted on 2023-06-12

2803 Enhanced perfusion following exposure to radiotherapy: a theoretical investigation

Köry, J.; Narain, V.; Stolz, B. J.; Kaeppler, J.; Markelc, B.; Muschel, R. J.; Maini, P. K.; Pitt-Francis, J. M.; Byrne, H. M.

10.1101/2023.06.12.544532 — systems biology — Posted on 2023-06-12

2804 Bioenergetic function is decreased in peripheral blood mononuclear cells of veterans with Gulf War Illness

Meyer, J. N.; Pan, W. K.; Ryde, I. T.; Alexander, T.; Klein-Adams, J. C.; Ndirangu, D. S.; Falvo, M. J.

10.1101/2023.06.07.544068 — pharmacology and toxicology — Posted on 2023-06-12

2805 SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response

Davies, J. P.; Sivadas, A.; Keller, K. R.; Wojcikiewicz, R. J.; Plate, L.

10.1101/2023.04.22.537917 — biochemistry — Posted on 2023-06-12

2806 Rare but not absent: the Inverted Mitogenomes of Deep-Sea Hatchetfish

Gomes-dos-Santos, A.; Vilas-Arrondo, N.; Machado, A. M.; Roman-Marcote, E.; Del Rio Iglesias, J. L.; Baldo, F.; Perez, M.; Fonseca, M. M.; C. Castro, L. F.; Froufe, E.

10.1101/2023.06.12.544378 — genomics — Posted on 2023-06-12

2807 Hypothalamic neuronal activation in primates drives naturalistic goal-directed eating behavior

Ha, L. J.; Yeo, H.-G.; Kim, Y. G.; Baek, I.; Baeg, E.; Lee, Y. H.; Won, J.; Jung, Y.; Park, J.; Jeon, C.-Y.; Kim, K.; Min, J.; Song, Y.; Park, J.-H.; Nam, K. R.; Son, S.; Yoo, S. B. M.; Park, S.-H. M.; Choi, W. S.; Lim, K. S.; Choi, J. Y.; Cho, J.-H.; Lee, Y.; Choi, H. J.

10.1101/2023.06.11.544288 — neuroscience — Posted on 2023-06-12

2808 Typical and disrupted small-world architecture and regional communication in full-term and preterm infants

Hu, H.; Coppola, P.; Stamatakis, E. A.; Naci, L.

10.1101/2023.06.12.544595 — neuroscience — Posted on 2023-06-12

2809 The novel nematicide chiricanine A suppresses Bursaphelenchus xylophilus pathogenicity in Pinus massoniana by inhibiting Aspergillus and its secondary metabolite, sterigmatocystin

Jia, J.; Chen, L.; Yu, W.; Su, J.

10.1101/2023.06.12.544558 — plant biology — Posted on 2023-06-12

2810 A comparative analysis of stably expressed genes across diverse angiosperms exposes flexibility in underlying promoter architecture

Yang, E. J. Y.; Maranas, C. J.; Nemhauser, J.

10.1101/2023.06.12.544596 — plant biology — Posted on 2023-06-12

2811 Labelizer: systematic selection of protein residues for covalent fluorophore labeling

Gebhardt, C.; Bawidamann, P.; Schuetze, K.; Moya Munoz, G. G.; Spring, A.-K.; Griffith, D.; Lipfert, J.; Cordes, T.

10.1101/2023.06.12.544586 — biophysics — Posted on 2023-06-12

2812 Evolutionary changes in the number of dissociable amino acids on spike proteins and nucleoproteins of SARS-CoV-2 variants

Bozic, A.; Podgornik, R.

10.1101/2023.03.12.532219 — biophysics — Posted on 2023-06-12

2813 PROTAC-Design-Evaluator (PRODE) -- An Advanced Method for in-silico PROTAC design

Geoffrey AS, B.; Agrawal, D.; Kulkarni, N.; Vetrivel, R.; Gurram, K.

10.1101/2023.06.12.544569 — bioinformatics — Posted on 2023-06-12

2814 Novel Imaging Guidance for Cholesteatoma Surgery usingTissue Autofluorescence

Yang, S.; Farrell, J.; Ye, S.; Ahmad, I.; Valdez, T. A.

10.1101/2023.06.12.544537 — bioengineering — Posted on 2023-06-12

2815 Characterization and super-resolution imaging of small tau aggregates in human samples.

Boken, D.; Cox, D.; Burke, M.; Lam, J. Y. L.; Katsinelos, T.; Danial, J. S. H.; McEwan, W. A.; Rowe, J.; Klenerman, D.

10.1101/2023.06.12.544575 — biochemistry — Posted on 2023-06-12

2816 Structural variation and DNA methylation shape the centromere-proximal meiotic crossover landscape in Arabidopsis

Fernandes, J. B.; Naish, M.; Lian, Q.; Burns, R.; Tock, A. J.; Rabanal, F. A.; Wlodzimierz, P.; Habring, A.; Nicholas, R. E.; Weigel, D.; Mercier, R.; Henderson, I. R.

10.1101/2023.06.12.544545 — genomics — Posted on 2023-06-12

2817 Can elevated plasma Adiponectin and Ghrelin counteract inflammation in the aging heart?

nahar, h.; Chandan, S.

10.1101/2023.06.11.544501 — cell biology — Posted on 2023-06-12

2818 Quantitative comparison of a mobile, tablet-based and two stationary, video-based eye-trackers

Koenig, A.; Bremmer, F.; Dowiasch, S.

10.1101/2023.06.12.544554 — neuroscience — Posted on 2023-06-12

2819 Vestibular mapping of the naturalistic head-centered motion spectrum

Ertl, M.; zu Eulenburg, P.; Woller, M.; Mayadali, U.; Boegle, R.; Dieterich, M.

10.1101/2023.06.12.544528 — neuroscience — Posted on 2023-06-12

2820 Pharmacological or genetic inhibition of Scn9a protects beta-cells while reducing insulin secretion in type 1 diabetes

Overby, P.; Provenzano, S.; Nahirney, N. S.; Dai, X.-Q.; Sun, W. G.; Xia, Y.; Kolic, J.; Macdonald, P. E.; Johnson, J. D.

10.1101/2023.06.11.544521 — physiology — Posted on 2023-06-12

2821 Deep learning-based survival prediction using DNA methylation-derived 3D genomic information

Yang, J.; Lee, D.; Koo, B.; Kim, S.

10.1101/2023.06.10.544450 — bioinformatics — Posted on 2023-06-12

2822 Virtual tissue microstructure reconstruction by deep learning and fluorescence microscopy

Bettancourt, N.; Perez, C.; Candia, V.; Guevara, P.; Kalaidzidis, Y.; Zerial, M.; Segovia-Miranda, F.; Morales-Navarrete, H.

10.1101/2023.06.12.544541 — bioinformatics — Posted on 2023-06-12

2823 Immuno-Engineered Mitochondria for Efficient Therapy of Acute Organ Injuries via Modulation of Inflammation and Cell Repair

Zhang, Q.; Shen, Y.; Zhang, H.; Yang, S.; Li, M. X.; Dai, C.; Yu, X.; Lou, J.; Zhang, C.; Feng, J.; Hu, C.; Lin, Z.; Li, X.; Zhou, X.

10.1101/2023.06.12.544181 — bioengineering — Posted on 2023-06-12

2824 Meniscus-enabled Projection Stereolithography (MAPS)

Kunwar, P.; Poudel, A.; Aryal, U.; Xie, R.; Geffert, Z. J.; Wittmann, H.; Chiang, T. H.; Maye, M. M.; Li, Z.; Soman, P.

10.1101/2023.06.12.544584 — bioengineering — Posted on 2023-06-12

2825 Direct 3D-bioprinting of hiPSC-derived cardiomyocytes to generate functional cardiac tissues

Esser, T. U.; Anspach, A.; Muenzebrock, K. A.; Kah, D.; Schruefer, S.; Schenk, J.; Heinze, K. G.; Schubert, D. W.; Fabry, B.; Engel, F. B.

10.1101/2023.06.12.544557 — bioengineering — Posted on 2023-06-12

2826 Comparative genetic, biochemical, and biophysical analyses of the four E. coli ABCF paralogs support distinct functions related to mRNA translation

Ousalem, F.; Singh, S.; Bailey, N. A.; Wong, K.-H.; Zhu, L.; Neky, M. J.; Sibindi, C.; Fei, J.; Gonzalez, R. L.; Boël, G.; Hunt, J. F.

10.1101/2023.06.11.543863 — biochemistry — Posted on 2023-06-12

2827 Flexibility of learning in complex worlds

Leimar, O.; Quinones, A. E.; Bshary, R.

10.1101/2023.06.12.544544 — animal behavior and cognition — Posted on 2023-06-12

2828 Prenatal alcohol exposure alters expression of genes involved in cell adhesion, immune response, and toxin metabolism in adolescent rat hippocampus

Khalifa, A.; Palu, R.; Perkins, A.; Volz, A.

10.1101/2023.06.12.544533 — genetics — Posted on 2023-06-12

2829 Membrane extraction in native lipid nanodiscs reveals dynamic regulation of Cdc42 complexes during cell polarization

Deutz, L. N.; Sarikaya, S.; Dickinson, D. J.

10.1101/2023.06.12.544590 — cell biology — Posted on 2023-06-12

2830 Mapping speech kinematics to brain activity with concurrent and time-registered measures of speech movements and brain function

Anastasopoulou, I.; Cheyne, D. O.; Lieshout, P. v.; Johnson, B. W.

10.1101/2023.06.12.544529 — neuroscience — Posted on 2023-06-12

2831 Resting-state EEG signatures of Alzheimer's disease are driven by periodic but not aperiodic changes

Kopcanova, M.; Tait, L.; Donoghue, T.; Stothart, G.; Smith, L.; Flores Sandoval, A. A.; Davila-Perez, P.; Buss, S.; Shafi, M. M.; Pascual-Leone, A.; Fried, P. J.; Benwell, C. S. Y.

10.1101/2023.06.11.544491 — neuroscience — Posted on 2023-06-12

2832 Designing function-specific minimal microbiomes from large microbial communities

Raghu, A. K.; Palanikumar, I.; Raman, K.

10.1101/2023.06.12.544531 — systems biology — Posted on 2023-06-12

2833 The fungal pathogen Ustilago maydis targets the maize corepressor TPL2 to modulate host transcription for tumorigenesis

Huang, L.; Oekmen, B.; Stolze, S. C.; Kastl, M.; Khan, M.; Hilbig, D.; Nakagami, H.; Djamei, A.; Doehlemann, G.

10.1101/2023.06.12.544564 — plant biology — Posted on 2023-06-12

2834 Hepatic lipid-associated macrophages mediate the protective effects of bariatric surgery against NASH

Fredrickson, G.; Florczak, K.; Barrow, F.; Dietsche, K.; Parthiban, P.; Almutlaq, R.; Abujamra, M.; Demirchian, M.; Wang, H.; Nguyen, H.; Adeyi, O.; Bartolomucci, A.; Staley, C.; Jahansouz, C.; Williams, J. W.; Mashek, D.; Ikramuddin, S.; Revelo, X.

10.1101/2023.06.11.544503 — physiology — Posted on 2023-06-12

2835 A subtle structural modification of a synthetic cannabinoid receptor agonist drastically increases its efficacy at the CB1 receptor

Yano, H.; Chitsazi, R.; Lucaj, C.; Tran, P.; Hoffman, A. F.; Baumann, M. H.; Lupica, C. R.; Shi, L.

10.1101/2023.06.10.544442 — pharmacology and toxicology — Posted on 2023-06-12

2836 In Vitro Reduction of Device Thrombosis Using a Combined Nitrite and Red Light Treatment

Alipour, E.; Jordan, J. E.; Files, D. C.; Kim-Shapiro, D.

10.1101/2023.06.10.544453 — pathology — Posted on 2023-06-12

2837 Comparative evaluation of straight and curved extension dialysis catheters for continuous renal replacement therapy in dogs with acute kidney injury

Bhat, A. A.; Chandrasekar, M.; Nambi, A. P.; Bhavani, S.; Kavitha, S.; Khan, F. A.

10.1101/2023.06.11.544513 — pathology — Posted on 2023-06-12

2838 AraENCODE: a comprehensive epigenomic database of Arabidopsis Thaliana

Wang, Z.; Liu, M.; Lai, F.; Fu, Q.; Xie, L.; Fang, Y.; Zhou, Q.; Li, G.

10.1101/2023.06.10.544382 — bioinformatics — Posted on 2023-06-12

2839 BRAKER3: Fully Automated Genome Annotation Using RNA-Seq and Protein Evidence with GeneMark-ETP, AUGUSTUS and TSEBRA

Gabriel, L.; Bruna, T.; Hoff, K. J.; Ebel, M.; Lomsadze, A.; Borodovsky, M.; Stanke, M.

10.1101/2023.06.10.544449 — bioinformatics — Posted on 2023-06-12

2840 Using a Riemannian elastic metric for statistical analysis of tumor cell shape heterogeneity

Li, W.; Prasad, A.; Miolane, N.; Dao Duc, K.

10.1101/2023.06.11.544518 — cell biology — Posted on 2023-06-12

2841 Engineering of human myotubes toward a mature metabolic and contractile phenotype

Dreher, S. I.; Grubba, P.; von Toerne, C.; Moruzzi, A.; Maurer, J.; Goj, T.; Birkenfeld, A. L.; Peter, A.; Loskill, P.; Hauck, S.; Weigert, C.

10.1101/2023.06.12.544344 — cell biology — Posted on 2023-06-12

2842 Temporal dynamics of honeybee learning and decision-making are revealed by a novel automated PER system

Strelevitz, H.; Tiraboschi, E.; Haase, A.

10.1101/2023.06.10.544458 — neuroscience — Posted on 2023-06-12

2843 Decoded EEG Neurofeedback-Guided Cognitive Reappraisal Training for Emotion Regulation

Li, L.; Gui, X.; Huang, G.; Zhang, L.; Han, X.; Liang, Z.; Zhang, Z.

10.1101/2023.06.10.544438 — neuroscience — Posted on 2023-06-12

2844 Soil chemical and microbial gradients determine accumulation of root exuded secondary metabolites and plant-soil feedbacks in the field

Gfeller, V.; Cadot, S.; Gulliver, S.; Waelchli, J.; Terrettaz, C.; Thoenen, L.; Mateo, P.; Robert, C.; Mascher, F.; Steinger, T.; Bigalke, M.; Erb, M.; Schlaeppi, K.

10.1101/2023.06.09.544436 — plant biology — Posted on 2023-06-12

2845 Diversity of hydrodynamic radii of intrinsically disordered proteins

Bialobrzewski, M. K.; Klepka, B. P.; Michas, A.; Cieplak-Rotowska, M. K.; Staszalek, Z.; Niedzwiecka, A.

10.1101/2023.06.12.543592 — biophysics — Posted on 2023-06-12

2846 Detecting haplotype-specific transcript variation in long reads with FLAIR2

Tang, A. D.; Hrabeta-Robinson, E.; Volden, R.; Vollmers, C.; Brooks, A. N.

10.1101/2023.06.09.544396 — bioinformatics — Posted on 2023-06-12

2847 Segmental Duplications Drive the Evolution of Accessory Regions in a Major Crop Pathogen

van Westerhoven, A.; Aguilera-Galvez, C.; Nakasato-Tagami, G.; Shi-Kunne, X.; Martinez de la Parte, E.; Chavarro Carero, E.; Meijer, H.; Feurtey, A.; Maryani, N.; Ordonez, N.; Schneider, H.; Nijbroek, K.; Wittenberg, A.; Hofstede, R.; Garcia-Bastidas, F.; Sorensen, A.; Swennen, R.; Stukenbrock, E.; Kema, G.; Seidl, M.

10.1101/2023.06.07.544053 — genomics — Posted on 2023-06-12

2848 A single DPE core promoter motif contributes to in vivo transcriptional regulation and affects cardiac function

Sloutskin, A.; Itzhak, D.; Vogler, G.; Ideses, D.; Alter, H.; Shachar, H.; Doniger, T.; Frasch, M.; Bodmer, R.; Duttke, S. H.; Juven-Gershon, T.

10.1101/2023.06.11.544490 — developmental biology — Posted on 2023-06-12

2849 A 2-million-year-old microbial and viral communities from the Kap Kobenhavn Formation in North Greenland

Fernandez-Guerra, A.; Borrel, G.; Delmont, T. O.; Elberling, B.; Eren, A. M.; Gribaldo, S.; Jochheim, A.; Henriksen, R. A.; Hinrichs, K.-U.; Korneliussen, T. S.; Krupovic, M.; Larsen, N. K.; Laso-Perez, R.; Pedersen, M. W.; Pedersen, V. K.; Sand, K. K.; Sikora, M.; Steinegger, M.; Veseli, I. A.; Wörmer, L.; Zhao, L.; Zure, M.; Kjaer, K. H.; Willerslev, E.

10.1101/2023.06.10.544454 — microbiology — Posted on 2023-06-12

2850 A novel signature of visual awareness independent of post-perceptual processing

Cohen, M. A.; Dembski, C.; Ortego, K.; Steinhilber, C.; Pitts, M.

10.1101/2023.06.09.543951 — neuroscience — Posted on 2023-06-12

2851 MitoSort: robust demultiplexing of pooled single-cell genomics data using endogenous germline mitochondrial variants

Tang, Z.; Zhang, W.; Shi, P.; Li, S.; Li, X.; Xu, Y.; Xu, J.

10.1101/2023.04.26.538392 — bioinformatics — Posted on 2023-06-12

2852 A multiplexed RT-PCR Assay for Nanopore Whole Genome Sequencing of Tilapia lake virus (TiLV)

Delamare-Deboutteville, J.; Watcharachai, M.; Pimsannil, K.; Sangpo, P.; Gan, H. M.; Khor Li Imm, L.; Mohan, C. V.; Dong, H. T.; Senapin, S.

10.1101/2023.04.24.537954 — genomics — Posted on 2023-06-12

2853 Systematic characterization of a non-transgenic Aβ1-42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice

Jimenez-Herrera, R.; Contreras, A.; Iborra-Lazaro, G.; Jeremic, D.; Djebari, S.; Navarro-Lopez, J. D.; Jimenez-Diaz, L. D.

10.1101/2023.05.09.539973 — neuroscience — Posted on 2023-06-12

2854 Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axis

Cikes, D.; Leutner, M.; Cronin, S. J. - F.; Novatchkova, M.; Pfleger, L.; Klepochova, R.; Rullman, E.; Gustafsson, T.; Hagelkrueys, A.; Knauf, C.; Moro, C.; Krebs, M.; Kautzky-Willer, A.; Krssak, M.; Orthofer, M.; Penninger, J. M.; Lair, B.; Lac, M.; Bergoglio, C.; Tavernier, G.; Bourlier, V.; Durnberger, G.; Roitinger, E.; Viguerie, N.

10.1101/2021.10.26.465828 — physiology — Posted on 2023-06-12

2855 Integrative Analysis of Epilepsy-Associated Genes Reveals Expression-Phenotype Correlations

Chi, W.; Kiskinis, E.

10.1101/2023.06.09.544142 — genomics — Posted on 2023-06-11

2856 How reliable are DAO supplements? A comparison of over-the-counter Diamine oxidase products

Alemany-Fornes, M.; Bori Dols, J.; Tintore, M.; Cune, J.; de Lecea, C.

10.1101/2023.04.13.536689 — molecular biology — Posted on 2023-06-12

2857 An intranuclear bacterial parasite of deep-sea musselsexpresses apoptosis inhibitors acquired from its host

Gonzalez Porras, M. A.; Assie, A.; Tietjen, M.; Violette, M.; Kleiner, M.; Gruber-Vodicka, H. R.; Dubilier, N.; Leisch, N.

10.1101/2023.06.11.544495 — microbiology — Posted on 2023-06-11

2858 Colonization and Dissemination of Klebsiella pneumoniae is Dependent on Dietary Carbohydrates

Hecht, A. L.; Harling, L. C.; Friedman, E. S.; Tanes, C.; Lee, J.; Firrman, J.; Tu, V.; Liu, L.; Bittinger, K.; Goulian, M.; Wu, G. D.

10.1101/2023.05.25.542283 — microbiology — Posted on 2023-06-11

2859 Mitochondrial networks of microglia adapt in a sex-specific manner upon injury-induced stress and UCP2 knockout

Maes, M. E.; Colombo, G.; Schoot Uiterkamp, F. E.; Sternberg, F.; Venturino, A.; Pohl, E. E.; Siegert, S.

10.1101/2022.08.22.504738 — neuroscience — Posted on 2023-06-12

2860 Investigating mitochondrial gene expression patterns in using network analysis to understand aging mechanisms

Mangoni, M.; Petrizzelli, F.; Liorni, N.; Bianco, S. D.; Biagini, T.; Napoli, A.; Adinolfi, M.; Guzzi, P. H.; Novelli, A.; Caputo, V.; Mazza, T.

10.1101/2023.05.16.540914 — bioinformatics — Posted on 2023-06-12

2861 DTX3L and USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels

Ashok, Y.; Mennerich, D.; Vela-Rodriguez, C.; Alanen, H. I.; Rall-Scharpf, M.; Wiesmuller, L.; Prunskaite-Hyyrylainen, R.; Lehtio, L.; Kietzmann, T.

10.1101/2023.01.30.526213 — biochemistry — Posted on 2023-06-12

2862 Neuron Enriched Exosomal MicroRNA Expression Profiles as a Marker of Early Life Alcohol Consumption

Yakovlev, V.; Lapato, D. M.; Rana, P.; Ghosh, P.; Roberson-Nay, R.

10.1101/2023.06.09.544235 — genetics — Posted on 2023-06-11

2863 A frameshift variant in the melanophilin gene is associated with loss of pigment from shed skin in ball pythons (Python regius)

Lederer, I.; Shahid, B.; Dao, U. M.; Brogdon, A.; Byrtus, H.; Delva, M.; Deva, O.; Hatfield, P.; Hertz, M.; Justic, J.; Mavor, S.; Pilbeam, E.; Rice, Z.; Simpson, A.; Temar, H.; Wynn, R.; Xhangolli, J.; Graves, C. W.; Seidel, H. S.

10.1101/2023.06.09.542917 — genetics — Posted on 2023-06-11

2864 Hippocampal memory reactivation during sleep is correlated with specific cortical states of the Retrosplenial and Prefrontal Cortices

Feliciano-Ramos, P. A.; Penagos, H.; Galazo, M.; Wilson, M.

10.1101/2023.06.11.544473 — neuroscience — Posted on 2023-06-12

2865 Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

Cheong, H. S. J.; Eichler, K.; Stuerner, T.; Asinof, S. K.; Champion, A. S.; Marin, E. C.; Oram, T. B.; Sumathipala, M.; Venkatasubramanian, L.; Namiki, S.; Siwanowicz, I.; Costa, M.; Berg, S.; Janelia FlyEM Project Team, ; Jefferis, G. S. X. E.; Card, G. M.

10.1101/2023.06.07.543976 — neuroscience — Posted on 2023-06-12

2866 On the Interaction of Biopotential Sensing and Right Leg Drive System with Electro-Quasistatic Human Body Communication

Sriram, S.; Polachan, K.; Sen, S.

10.1101/2022.06.13.495999 — bioengineering — Posted on 2023-06-12

2867 Genome-wide association studies reveal a rapidly evolving candidate avirulence effector in the Cercospora leaf spot pathogen Cercospora beticola

CHEN, C.; Keunecke, H.; Bemm, F.; Gyetvai, G.; Neu, E.; Kopisch-Obuch, F. J.; McDonald, B.; Stapley, J.

10.1101/2023.06.11.544483 — evolutionary biology — Posted on 2023-06-11

2868 Evolutionary history of Calcium-sensing receptors sheds light into hyper/hypocalcemia-causing mutations

Bircan, A.; Kuru, N.; Dereli, O.; Adebali, O.

10.1101/2023.06.11.544489 — evolutionary biology — Posted on 2023-06-11

2869 Cholinergic input to mouse visual cortex signals a movement state and acutely enhances layer 5 responsiveness

Yogesh, B.; Keller, G. B.

10.1101/2023.06.07.543871 — neuroscience — Posted on 2023-06-12

2870 Activation of M1 cholinergic receptors in mouse somatosensory cortex enhances information processing and improves detection behaviour

Mishra, W.; Kheradpezhouh, E.; Arabzadeh, E.

10.1101/2023.06.06.543981 — neuroscience — Posted on 2023-06-12

2871 Clinical Knowledge and Reasoning Abilities of AI Large Language Models in Pharmacy: A Comparative Study on the NAPLEX Exam

Angel, M.; Patel, A.; Alachkar, A.; Baldi, P. F.

10.1101/2023.06.07.544055 — scientific communication and education — Posted on 2023-06-12

2872 Phosphoprotein dynamics of interacting tumor and T cells by HySic

Ibanez-Molero, S.; Pruijs, J.; Atmopawiro, A.; Wang, F.; Altelaar, M.; Peeper, D. S.; Stecker, K. E.

10.1101/2023.06.05.541905 — cancer biology — Posted on 2023-06-11

2873 Spatiotemporal Transcriptomes of Pig Hearts Reveal Midkine-Mediated Vascularization in a Chronic Myocardial Infarcted Model

Adusumalli, S.; Lim, S.; Ren, V.; Chong, L. Y.; Tan, C.; Tham, R.; Ye, L.; Wang, Y.; Petretto, E.; Tryggvason, K.; Yap, L.

10.1101/2023.06.10.544480 — bioinformatics — Posted on 2023-06-11

2874 The distress context of social calls evokes a fear response in the bat Pipistrellus abramus

Yoshino-Hashizawa, K.; Nishiuchi, Y.; Hiragochi, M.; Kihara, M.; Kobayasi, K. I.; Hiryu, S.

10.1101/2023.06.11.544437 — animal behavior and cognition — Posted on 2023-06-11

2875 Evolution of the gene regulatory network of body axis by enhancer hijacking in amphioxus

Shi, C.; Chen, S.; Liu, H.; Li, S.; Wang, Y.; Pan, R.; Wu, X.; Li, X.; Li, J.; Xing, C.; Liu, X.; Wang, Y.; Qu, Q.; Li, G.

10.1101/2023.06.11.544506 — evolutionary biology — Posted on 2023-06-11

2876 Genome duplications, genomic conflict, and rapid phenotypic evolution characterize the Cretaceous radiation of Fagales

Yang, Y.-Y.; Stull, G. W.; Qu, X.; Zhao, L.; Hu, Y.; Wang, Z.; Ma, H.; Li, D.; Smith, S. A.; Yi, T.

10.1101/2023.06.11.544004 — evolutionary biology — Posted on 2023-06-12

2877 13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8+ T cells

Ma, E. H.; Dahabieh, M. S.; DeCamp, L. M.; Kaymak, I.; Kitchen-Goosen, S. M.; Roy, D. G.; Verway, M. J.; Johnson, R. M.; Samborska, B.; Scullion, C. A.; Steadman, M.; Vos, M.; Roddy, T. P.; Krawczyk, C. M.; Williams, K. S.; Sheldon, R. D.; Jones, R. G.

10.1101/2023.06.09.544407 — immunology — Posted on 2023-06-11

2878 Targeting CD301+ macrophage inhibits endometrial fibrosis and improves pregnancy outcome

Lv, H.; Sun, H.; Wang, L.; Yao, S.; Liu, D.; Zhang, X.; Pei, Z.; Zhou, J.; Wang, H.; Dai, J.; Yan, G.; Ding, L.; Wang, Z.; Cao, C.; Zhao, G.; Hu, Y.

10.1101/2023.06.09.544336 — immunology — Posted on 2023-06-11

2879 Select EZH2 inhibitors enhance the viral mimicry effects of DNMT inhibition through a mechanism involving calcium-calcineurin-NFAT signaling

Chomiak, A. A.; Tiedemann, R.; Liu, Y.; Kong, X.; Cui, Y.; Thurlow, K.; Cornett, E. M.; Topper, M. J.; Baylin, S.; Rothbart, S. B.

10.1101/2023.06.09.544393 — cancer biology — Posted on 2023-06-11

2880 Content-enriched fluorescence lifetime fluctuation spectroscopy to study bio-molecular condensate formation

Perego, E.; Zappone, S.; Castagnetti, F.; Mariani, D.; Vitiello, E.; Rupert, J.; Zacco, E.; Tartaglia, G. G.; Bozzoni, I.; Slenders, E.; Vicidomini, G.

10.1101/2023.06.09.544221 — biophysics — Posted on 2023-06-11

2881 Parthenogenesis, sexual conflict and the evolution of oogamy

Liu, X.; Pitchford, J. W.; Constable, G. W. A.

10.1101/2023.06.09.544312 — evolutionary biology — Posted on 2023-06-11

2882 Weak local adaptation to drought in seedlings of a widespread conifer

Candido-Ribeiro, R.; Aitken, S. N.

10.1101/2023.06.09.544307 — evolutionary biology — Posted on 2023-06-11

2883 The effects of data leakage on neuroimaging predictive models

Rosenblatt, M.; Tejavibulya, L.; Jiang, R.; Noble, S.; Scheinost, D.

10.1101/2023.06.09.544383 — neuroscience — Posted on 2023-06-11

2884 Increasing the reliability of functional connectivity by predicting long-scan functional connectivity based on short-scan functional connectivity: model exploration, explanation, validation, and application.

Hu, B.; Yu, Y.; Li, Y.-T.; Wu, K.; Wang, X.-T.; Yan, L.-F.; Wang, W.; Cui, G.-B.

10.1101/2023.06.09.544367 — neuroscience — Posted on 2023-06-11

2885 Effects of linker length on phase separation: lessons from the Rubisco-EPYC1 system of the algal pyrenoid

GrandPre, T.; Zhang, Y.; Pyo, A. G. T.; Weiner, B.; Li, J.-L.; Jonikas, M. C.; Wingreen, N. S.

10.1101/2023.06.11.544494 — biophysics — Posted on 2023-06-11

2886 Protein Dynamics Govern the Oxyferrous State Lifetime of an Artificial Oxygen Transport Protein

Zhang, L.; Brown, M. C.; Mutter, A. C.; Greenland, K. N.; Cooley, J. W.; Koder, R. L.

10.1101/2023.06.09.544418 — biophysics — Posted on 2023-06-11

2887 Gene family evolution in brassicaceous-feeding insects: Implications for adaptation and host plant range.

Ravikanthachari, N.; Boggs, C. L.

10.1101/2023.06.09.544424 — evolutionary biology — Posted on 2023-06-11

2888 Assessment of long-term trends in a threatened grassland bird community using daily bird lists

Bharadwaj, A.; Mhamane, S.; Bangal, P.; Menon, T.; Isvaran, K.; Quader, S.

10.1101/2022.10.31.514489 — ecology — Posted on 2023-06-11

2889 In Vitro Culture Alters Cell Lineage Composition and Cellular Metabolism of Bovine Blastocyst

Ming, H.; Zhang, M.; Rajput, S.; Logsdon, D.; Zhu, L.; Schoolcraft, W. B.; Krisher, R. L.; Jiang, Z.; Yuan, Y.

10.1101/2023.06.09.544379 — developmental biology — Posted on 2023-06-11

2890 Hippo Signaling Modulates Mechano-inflammatory Responses of Chondrocytes

Cai, X.; Warburton, C.; Perez, O. F.; Wang, Y.; Ho, L.; Finelli, C.; Wu, C.; Rodriguez, C. D.; Kaplan, L.; Best, T. M.; Huang, C.-Y.; Meng, Z.

10.1101/2023.06.09.544419 — cell biology — Posted on 2023-06-11

2891 Rescuing missing data in connectome-based predictive modeling

Liang, Q.; Jiang, R.; Adkinson, B. D.; Rosenblatt, M.; Mehta, S.; Foster, M. L.; Dong, S.; You, C.; Negahban, S.; Zhou, H. H.; Chang, J.; Scheinost, D.

10.1101/2023.06.09.544392 — neuroscience — Posted on 2023-06-11

2892 Motion direction is represented as a bimodal probability distribution in the human visual cortex

Chetverikov, A.; Jehee, J. F. M.

10.1101/2023.06.05.543672 — neuroscience — Posted on 2023-06-11

2893 The Mechanism and Energetics of the Dynein Priming Stroke

Golcuk, M.; Yilmaz, S. Z.; Yildiz, A.; Gur, M.

10.1101/2023.06.10.544469 — biophysics — Posted on 2023-06-11

2894 Computational prediction of gamma-oryzanol as potential agonist of human peroxisome proliferator-activated receptor gamma (ppar-γ)

Biswal, P. K.; Behera, S.; Mohapatra, S.; Kar, D. M.; Samanta, L.; Behera, P. M.; Kar, R. K.

10.1101/2023.06.10.542647 — bioinformatics — Posted on 2023-06-11

2895 Molecular imaging with aquaporin-based reporter genes: quantitative considerations from Monte Carlo diffusion simulations

Chowdhury, R.; Wan, J.; Gardier, R. M. M.; Rafael-Patino, J.; Thiran, J.-P.; Gibou, F.; Mukherjee, A.

10.1101/2023.06.09.544324 — bioengineering — Posted on 2023-06-11

2896 Homologous chromosome recognition via nonspecific interactions

Marshall, W. F.; Fung, J. C.

10.1101/2023.06.09.544427 — cell biology — Posted on 2023-06-11

2897 HES1 and ID3 temporally regulate p27 levels and endothelial cell flow-mediated quiescence depth

Tanke, N.; Liu, Z.; Yu, T.; Oatley, M.; Bougaran, P.; Quigley, K.; Cook, J. G.; Bautch, V. L.

10.1101/2023.06.09.544403 — cell biology — Posted on 2023-06-11

2898 BIFROST: a method for registering diverse imagingdatasets

Brezovec, L. E.; Berger, A. B.; Hao, Y. A.; Lin, A.; Ahmed, O. M.; Pacheco, D. A.; Thiberge, S. Y.; Murthy, M.; Clandinin, T. R.

10.1101/2023.06.09.544408 — neuroscience — Posted on 2023-06-11

2899 A Transient High-dimensional Geometry Affords Stable Conjunctive Subspaces for Efficient Action Selection

Kikumoto, A.; Bhandari, A.; Shibata, K.; Badre, D.

10.1101/2023.06.09.544428 — neuroscience — Posted on 2023-06-11

2900 Kinetic modeling of leucine-mediated signaling and protein metabolism in human skeletal muscle

McColl, T. J.; Clarke, D. C.

10.1101/2023.06.10.544441 — systems biology — Posted on 2023-06-11

2901 T- and L-type calcium channels maintain calcium oscillations in the murine zona glomerulosa

Dinh, H. A.; Volkert, M.; Secener, A. K.; Scholl, U. I.; Stölting, G.

10.1101/2023.06.09.544326 — physiology — Posted on 2023-06-11

2902 Single-cell RNA sequencing identifies response of renal lymphatic endothelial cells to acute kidney injury

Creed, H. A.; Kannan, S.; Tate, B. L.; Banerjee, P.; Mitchell, B. M.; Chakraborty, S.; Rutkowski, J. M.

10.1101/2023.06.09.544380 — pathology — Posted on 2023-06-11

2903 Eclipse: Alignment of Two or More Nontargeted LC-MS Metabolomics Datasets using Directed Subalignments

Hitchcock, D. S.; Krejci, J. N.; Dennis, C. A.; Jeanfavre, S. T.; Avila-Pacheco, J. R.; Clish, C. B.

10.1101/2023.06.09.544417 — bioinformatics — Posted on 2023-06-11

Smith, I.; Smirnov, P.; Haibe-Kains, B.

10.1101/2023.06.09.544397 — bioinformatics — Posted on 2023-06-11

2905 Analysis of Body-Fin Cooperative Propulsion Mechanism of Koi Carp Using Pose Estimation

Wu, X.; Wang, Y.; Huang, J.; Wang, L.

10.1101/2022.09.07.507033 — animal behavior and cognition — Posted on 2023-06-11

2906 Monocytes use protrusive forces to generate migration paths in viscoelastic collagen-based extracellular matrices

Adebowale, K.; Ha, B.; Saraswathibhatla, A.; Indana, D.; Popescu, M.; Demirdjian, S.; Yang, J.; Bassik, M. C.; Franck, C.; Bollyky, P.; Chaudhuri, O.

10.1101/2023.06.09.544394 — cell biology — Posted on 2023-06-11

2907 Hydraulic Conductivity of The Hemp Stems Under Water Stress

Yuksel, M.; Al-agele, H. A.; Nackley, L.; Higgins, C.

10.1101/2023.06.09.544341 — cell biology — Posted on 2023-06-11

2908 Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules

Ma, B.; Khan, K. S.; Xu, T.; Amada, J. X.; Guo, Z.; Yan, Y.; Cheng, A. S.-L.; Ng, B. W.-L.

10.1101/2023.06.09.544275 — cell biology — Posted on 2023-06-11

2909 NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

Waqas, F. H.; Shehata, M.; Elgaher, W. A. M.; Lacour, A.; Kurmasheva, N.; Begnini, F.; Kiib, A. E. K. E.; Dahlmann, J.; Chen, C.; Poulsen, T. B.; Merkert, S.; Martin, U.; Olmer, R.; Olagnier, D.; Hirsch, A.; Pleschka, S.; Pessler, F.

10.1101/2023.06.11.544457 — microbiology — Posted on 2023-06-11

2910 Neuropathy target esterase activity predicts retinopathy among PNPLA6 disorders

Liu, J.; He, Y.; Lwin, C.; Han, M.; Guan, B.; Niak, A.; Bender, C.; Moore, N.; Huryn, L. A.; Sergeev, Y.; Qian, H.; Zeng, Y.; Dong, L.; Liu, P.; Li, J.; Haugen, C. J.; Prasov, L.; Shi, R.; Dollfus, H.; Aristodemou, P.; Laich, Y.; Nemeth, A. H.; Taylor, J.; Downes, S.; Krawczynski, M.; Meunier, I.; Strassberg, M.; Tenney, J.; Gao, J.; Shear, M. A.; Moore, A. T.; Duncan, J. L.; Menendez, B.; Hull, S.; Vincent, A.; Siskind, C. E.; Traboulsi, E. I.; Blackstone, C.; Sisk, R.; Utz, V.; Webster, A. R.; Michaelides, M.; Arno, G.; Synofzik, M.; Hufnagel, R. B.

10.1101/2023.06.09.544373 — neuroscience — Posted on 2023-06-11

2911 A translational rodent model of individual differences in sensitivity to the aversive properties of ethanol

Przybysz, K. R.; Ramirez, L. A.; Pitock, J. R.; Starr, E. M.; Yang, H.; Glover, E. J.

10.1101/2023.06.08.544209 — neuroscience — Posted on 2023-06-11

2912 Alternative splicing of a potato disease resistance gene maintains homeostasis between development and immunity, and functions as a novel process for pathogen surveillance

Sun, B.; Huang, J.; Gao, C.; Li, K.; Zhao, F.; Kong, L.; Wang, L.; Shen, J.; Wang, Y.; Halterman, D.; Dong, S.

10.1101/2023.06.09.544375 — plant biology — Posted on 2023-06-11

2913 An atlas of protein homo-oligomerization across domains of life

Schweke, H.; Levin, T.; Pacesa, M.; Goverde, C. A.; Kumar, P.; Duhoo, Y.; Dornfeld, L. J.; Dubreuil, B.; Georgeon, S.; Ovchinnikov, S.; Woolfson, D. N.; Correia, B. E.; Dey, S.; Levy, E. D.

10.1101/2023.06.09.544317 — bioinformatics — Posted on 2023-06-11

2914 From gonadogenesis to testicular cancer: Unravelling the novel regulators and identification of drug candidates against FGF9 and PTGDS

Kumar, C.; Singh, V. K.; Roy, J. K.

10.1101/2023.06.09.544377 — bioinformatics — Posted on 2023-06-11

2915 Cyclic mechanical stretching stimuli promotes angiocrine signals during in vitro liver bud formation from human pluripotent stem cells

Yoshimoto, K.; Maki, K.; Adachi, T.; Kamei, K.-i.

10.1101/2023.06.11.544492 — bioengineering — Posted on 2023-06-11

2916 Mag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome

Wu, C. C.; Tsantilas, K. A.; Park, J.; Plubell, D. L.; Naicker, P.; Govender, I.; Buthelezi, S.; Stoychev, S.; Jordaan, J.; Merrihew, G. E.; Huang, E.; Parker, E. D.; Riffle, M.; Hoofnagle, A. N.; MacCoss, M. J.

10.1101/2023.06.10.544439 — biochemistry — Posted on 2023-06-11

2917 Absolute quantification of photoreceptor outer segment proteins

Skiba, N. P.; Lewis, T. R.; Spencer, W. J.; Castillo, C. M.; Shevchenko, A.; Arshavsky, V. Y.

10.1101/2023.01.19.524794 — biochemistry — Posted on 2023-06-11

2918 Dose-dependent interaction of parasites with tiers of host defence generates "wormholes" that prolong infection at intermediate inoculum sizes

Graham, A. L.; Regoes, R. R.

10.1101/2023.06.09.544354 — ecology — Posted on 2023-06-11

2919 IL-22 promotes acute kidney injury through activation of the DNA damage response and cell death in proximal tubule cells

Taguchi, K.; Sugahara, S.; Elias, B. C.; Pabla, N. S.; Canaud, G.; Brooks, C. R.

10.1101/2023.06.08.544134 — cell biology — Posted on 2023-06-11

2920 PP2A-B55SUR-6 promotes nuclear envelope breakdown in C. elegans embryos

Kapoor, S.; Adhikary, K.; Kotak, S.

10.1101/2023.06.11.544482 — cell biology — Posted on 2023-06-11

2921 Zfp318 controls the recallability of memory B cells

Wang, Y.; Shao, W.; Liu, X.; Liang, Q.; Lei, J.; Mei, M.; Li, Y.; Tan, X.; Yu, G.; Li, Y.; Zhang, L.; Qi, H.

10.1101/2023.06.11.542551 — immunology — Posted on 2023-06-11

2922 Single-cell transcriptional analysis of lamina propria lymphocytes in the jejunum reveals ILC-like cells in pigs

Wang, J.; Cheng, M.; Gao, M.; Sun, Y.; Lu, Y.; Li, X.; Shi, C.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Wang, C.; Cao, X.

10.1101/2023.01.01.522424 — immunology — Posted on 2023-06-11

2923 An Interleukin 9-Zbtb18 axis promotes germinal center development of memory B cells

Luo, X.; Hou, X.; Wang, Y.; Li, Y.; Yu, S.; Qi, H.

10.1101/2023.06.11.544304 — immunology — Posted on 2023-06-11

2924 Expansion-assisted selective plane illumination microscopy for nanoscale imaging ofcentimeter-scale tissues

10.1101/2023.06.08.544277 — neuroscience — Posted on 2023-06-11

2925 Noncoding RNAs evolutionarily extend animal lifespan

Wang, A.

10.1101/2023.06.09.544283 — bioinformatics — Posted on 2023-06-11

2926 Physicochemical, functional, and evolutionary characteristics of protein loop regions in human and Escherichia coli proteomes

Zhang, L.; Nishi, H.

10.1101/2023.06.09.544332 — bioinformatics — Posted on 2023-06-11

2927 Functional diversity reduces the risk of hydraulic failure in tree mixtures through hydraulic disconnection

Moreno, M.; Simioni, G.; Cochard, H.; Doussan, C.; Guillemot, J.; Decarsin, R.; Fernandez, P.; Dupuy, J.-L.; Trueba, S.; Pimont, F.; Ruffault, J.; Martin-StPaul, N. K.

10.1101/2023.06.09.544345 — ecology — Posted on 2023-06-11

2928 Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules

Ma, B.; Khan, K. S.; Xu, T.; Amada, J. X.; Guo, Z.; Yan, Y.; Cheng, A.; Ng, W.-L.

10.1101/2023.06.09.544275 — cell biology — Posted on 2023-06-11

2929 Comparing kinetic proofreading and kinetic segregation for T cell receptor activation

Moffett, A. S.; Ganzinger, K. A.; Eckford, A.

10.1101/2023.06.11.544497 — immunology — Posted on 2023-06-11

2930 Cell-free chromatin particles activate immune checkpoints in human T cells: Implications for cancer therapy

Shabrish, S.; Pal, K.; Khare, N. K.; Satsangi, D.; Pilankar, A.; Jadhav, V.; Shinde, S.; Raphael, N.; Sriram, G.; Lopes, R.; Raghuram, G. V.; Tandel, H.; Mittra, I.

10.1101/2023.06.09.544311 — immunology — Posted on 2023-06-11

2931 On the Mathematics of RNA Velocity II: Algorithmic Aspects

Li, T.; Wang, Y.; Guoguo, Y.; Zhou, P.

10.1101/2023.06.09.544270 — bioinformatics — Posted on 2023-06-11

2932 Identifying gastric cancer molecular subtypes by integrating DNA-based hierarchical classification strategy and clinical stratification

Yang, B.; Liu, S.; Xie, J.; Tang, X.; Guan, P.; Zhu, Y.; Xia, L. C.

10.1101/2023.06.09.544302 — bioinformatics — Posted on 2023-06-11

2933 Impacts of urban stressors on freshwater biofilms

Vrba, R.; Lavoie, I.; Creusot, N.; Eon, M.; Millan-Navarro, D.; Feurtet-Mazel, A.; Mazzella, N.; Moreira, A.; Planas, D.; Morin, S.

10.1101/2023.06.11.544504 — ecology — Posted on 2023-06-11

2934 Increased dispersal explains increasing local diversity with global biodiversity declines

Fagan, B.; Pitchford, J. W.; Stepney, S.; Thomas, C. D.

10.1101/2023.06.09.544194 — ecology — Posted on 2023-06-11

2935 Ablation of Max expression induces meiotic onset in sexually undifferentiated germ cells

Suzuki, A.; Uranishi, K.; Nishimoto, M.; Mizuno, Y.; Mizuno, S.; Takahashi, S.; Eisenman, R. N.; Okuda, A.

10.1101/2023.06.10.544477 — developmental biology — Posted on 2023-06-11

2936 Comparative analysis of gonadal transcriptomes between turtle and alligator identifies common molecular cues activated during the temperature-sensitive period for sex determination

Toyota, K.; Akashi, H.; Ishikawa, M.; Yamaguchi, K.; Shigenobu, S.; Sato, T.; Lange, A.; Tyler, C. R.; Iguchi, T.; Miyagawa, S.

10.1101/2023.06.09.544319 — developmental biology — Posted on 2023-06-11

2937 Nuclear aging in polyglutamine-induced neurodegeneration

Pereira, D.; Cunha-Santos, J.; Vasconcelos-Ferreira, A.; Duarte-Neves, J.; Onofre, I.; Carmona, V.; Aveleira, C.; Lopes, S. M.; Lobo, D. D.; Martins, I. M.; Goncalves, N.; Cavadas, C.; Pereira de Almeida, L.

10.1101/2023.06.09.544056 — neuroscience — Posted on 2023-06-11

2938 Gauge equivariant convolutional neural networks for diffusion mri

Hussain, U.; Khan, A.

10.1101/2023.06.09.544263 — neuroscience — Posted on 2023-06-11

2939 Genomics resolves historical uncertainties on phylogenetics and accommodates the systematics of marmosets and Goeldi's monkey (Primates: Platyrrhini)

Costa-Araujo, R.; Roos, C.; Rohe, F.; Silva-Jr, J. d. S.; Freitas, P. D.; Pissinatti, A.; Boubli, J. P.; Farias, I. P.; Hrbek, T.

10.1101/2023.06.10.544470 — zoology — Posted on 2023-06-11

2940 A dataset of new occurrence records of primates from the arc of deforestation, Brazil

Costa-Araujo, R.; Canale, G. R.; Melo, F. R. d.; Silva, R. R. d.; Silva, I. B. d.; Alencar, R. M. d.; Silva, L. F. d.; Jerusalinsky, L.; Azevedo, R. B. d.; Junior, E. M. S.; Mourthe, I.; Ruz, E. J. H.; Silva-Jr., J. d. S. e.; Roos, C.; Farias, I. P.; Hrbek, T.

10.1101/2023.06.11.544487 — zoology — Posted on 2023-06-11

2941 Improved Production of Taxol(R) Precursors in S. cerevisiae using Combinatorial in silico Design and Metabolic Engineering

MALCI, K.; Santibanez, R.; Jonguitud-Borrego, N.; Santoyo-Garcia, J. H.; Kherkoven, E. J.; Rios Solis, L.

10.1101/2023.06.11.544475 — synthetic biology — Posted on 2023-06-11

2942 Spatiotemporal Transcriptomes of Pig Hearts Reveal Midkine-Mediated Vascularization in a Chronic Myocardial Infarcted Model

Adusumalli, S.; Lim, S.; Ren, V.; Chong, L. Y.; Tham, R.; Ye, L.; Wang, Y.; Petretto, E.; Tryggvason, K.; Yap, L.

10.1101/2023.06.10.544480 — bioinformatics — Posted on 2023-06-11

2943 cProSite: A web based interactive platform for online proteomics, phosphoproteomics, and genomics data analysis

Lowy, D. R.; Wang, D.; Qian, X.; Du, Y.-C. N.; Sanchez-Solana, B.; Chen, K.; Kanigicherla, M.; Jenkins, L. M.; Luo, J.; Eng, S.; Brian, P.; Chen, B.; Yao, X.; Nguyen, T.; Tripathi, B. K.; Durkin, M. R.

10.1101/2023.06.10.543932 — bioinformatics — Posted on 2023-06-11

2944 Biomimetic robots reveal flexible adjustment of sexual signalling in a wild invertebrate.

Wilde, J. A.; Darden, S. K.; Hart, J. D.; Weiss, M. N.; Ellis, S.; Fawcett, T. W.

10.1101/2023.06.11.544488 — animal behavior and cognition — Posted on 2023-06-11

2945 Plant-mycorrhizal associations may explain the latitudinal gradient of plant community assembly

Shinohara, N.; Kobayashi, Y.; Nishizawa, K.; Kadowaki, K.; Yamawo, A.

10.1101/2023.06.10.544476 — ecology — Posted on 2023-06-11

2946 Comparative Interactome Analysis of α-arrestin Families in Human and Drosophila

Lee, K.-T.; Pranoto, I. K.; Kim, S.-Y.; Choi, H.-J.; To, N. B.; Chae, H.; Lee, J.-Y.; Kim, J.-E.; Kwon, Y. V.; Nam, J.-W.

10.1101/2023.06.11.544486 — cell biology — Posted on 2023-06-11

2947 Photoperiod regulates gonadotrope cell division in medaka via melatonin, Tsh and folliculostellate cells

Royan, M. R.; Hodne, k.; Rasoul, N.-l.; Weltzien, F.-A.; Henkel, C.; Fontaine, R.

10.1101/2023.06.09.544159 — neuroscience — Posted on 2023-06-11

2948 Developmental transcriptional control of mitochondrial homeostasis is required for activity-dependent synaptic connectivity

Mohylyak, I.; Bengochea, M.; Caro, C. P.; Asfogo, N.; Topp, S. F.; Danda, N.; Atak, Z. K.; De Waegeneer, M.; Placais, P.-Y.; Preat, T.; Aerts, S.; Corti, O.; de Juan-Sanz, J.; Hassan, B. A.

10.1101/2023.06.11.544500 — neuroscience — Posted on 2023-06-11

2949 Assessing the Accuracy of a Smart Collar for Dogs: Predictive Performance for Heart and Breathing Rates on a Large Scale Dataset

Jarkoff, H.; Lorre, G.; Humbert, E.

10.1101/2023.06.09.544347 — physiology — Posted on 2023-06-11

2950 Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical pediatric glioma

Mukherjee, P.; Greenwood, B.; Henao, J.; Kiebish, M. A.; Seyfried, T. N.

10.1101/2023.06.09.544252 — cancer biology — Posted on 2023-06-11

2951 PlotS: web-based application for data visualization and analysis

Jajo, R.; Kansal, S.; Balyan, S.; Raghuvanshi, S.

10.1101/2023.06.09.544161 — bioinformatics — Posted on 2023-06-11

2952 A Gpr35 tuned gut-brain metabolic axis regulates depressive-like behavior

Cheng, L.; Wu, H.; Cai, X.; Wang, Q.; Zhang, Y.; Yin, Z.; Yan, Q.; Hou, Y.; Yuan, Y.; Wang, G.; Zhang, X.; Hao, H.; Zheng, X.

10.1101/2023.06.11.542602 — animal behavior and cognition — Posted on 2023-06-11

2953 The evolutionary history of the common bean (Phaseolus vulgaris) revealed by chloroplast and nuclear genomes.

Frascarelli, G.; Galise, T. R.; D'Agostino, N.; Cafasso, D.; Cozzolino, S.; Cortinovis, G.; Sparvoli, F.; Bellucci, E.; Di Vittori, V.; Nanni, L.; Pieri, A.; Rossato, M.; Vincenzi, L.; Benazzo, A.; Delledonne, M.; Bitocchi, E.; Papa, R.

10.1101/2023.06.09.544374 — genetics — Posted on 2023-06-11

2954 Scalable in-vitro immunostimulation of human blood for in-depth profiling of acute immune response effects

Reitzner, S. M.; Mikes, J.; Brodin, P.

10.1101/2023.06.08.544193 — immunology — Posted on 2023-06-11

2955 Effects of different immunomodulating liposome-based adjuvants and injection sites on immunogenicity in pigs

Stastna, E.; Erbs, G.; Skovgaard, K.; Jakobsen, J. T.; Pedersen, G. K.; Jungersen, G.

10.1101/2023.06.08.544239 — immunology — Posted on 2023-06-11

2956 When Neural Activity Fails to Reveal Causal Contributions

Fakhar, K.; Dixit, S.; Hadaeghi, F.; Kording, K. P.; Hilgetag, C. C.

10.1101/2023.06.06.543895 — neuroscience — Posted on 2023-06-11

2957 Differential activity patterns in the upper and lower blade of the dentate gyrus

Fredes, F.; Masaracchia, L.; Capogna, M.; Vidaurre, D.

10.1101/2023.06.07.544044 — neuroscience — Posted on 2023-06-11

2958 Age-dependent modulation of the excitability of layer V pyramidal neurons by dopamine D1 receptors in mices primary motor cortex

Plateau, V.; Baufreton, J.; Le Bon-Jego, M.

10.1101/2023.06.06.543824 — neuroscience — Posted on 2023-06-11

2959 Modality-independent effect of gravity in shaping the internal representation of 3D space

Theo, M.; Gabriela, H. A.; Leonardo, A.; Gilles, C.; Mathieu, B.; Joseph, M.; Michele, T.

10.1101/2020.03.23.003061 — neuroscience — Posted on 2023-06-11

2960 AutoMacq: an automatic pipeline to analyse macaque structural MRI data

Kindred, N.; Carella, S.; van den Heuvel, M. P.; Balezeau, F.; Wang, Y.; Poirier, C.

10.1101/2023.06.06.543846 — neuroscience — Posted on 2023-06-11

2961 Common computations in automatic cue combination and metacognitive confidence reports

Gao, Y.; Xue, K.; Odegaard, B.; Rahnev, D.

10.1101/2023.06.07.544029 — neuroscience — Posted on 2023-06-11

2962 Multidimensional analysis of a social behavior identifies regression and phenotypic heterogeneity in a female mouse model for Rett syndrome

Mykins, M.; Bridges, B.; Jo, A.; Krishnan, K.

10.1101/2023.06.05.543804 — neuroscience — Posted on 2023-06-11

2963 Maturation-dependent changes in cortical and thalamic activity during slow waves of light sleep: insights from a combined EEG-fMRI study

Bergamo, D.; Handjaras, G.; Petruso, F.; Talami, F.; Ricciardi, E.; Benuzzi, F.; Vaudano, A. E.; Meletti, S.; Bernardi, G.; Betta, M.

10.1101/2023.06.07.542852 — neuroscience — Posted on 2023-06-11

2964 Concerted epithelial and stromal changes during progression of Barrett's Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysis

Strasser, M.; Gibbs, D. L.; Gascard, P.; Bons, J.; Hickey, J. W.; Schürch, C. M.; Tan, Y.; Black, S.; Chu, P.; Ozkan, A.; Basisty, N.; Sangwan, V.; Rose, J.; Shah, S.; Camilleri-Broet, S.; Fiset, P.-O.; Bertos, N.; Berube, J.; Djambazian, H.; Li, R.; Oikonomopoulos, S.; Fels-Elliott, D. R.; Vernovsky, S.; Shimshoni, E.; Collyar, D.; Russell, A.; Ragoussis, I.; Stachler, M.; Goldenring, J. R.; McDonald, S.; Ingber, D. E.; Schilling, B.; Nolan, G. P.; Tlsty, T. D.; Huang, S.; Ferri, L. L.

10.1101/2023.06.08.544265 — cancer biology — Posted on 2023-06-11

2965 Machine learning to construct an mRPS risk prognostic model for directing immunotherapy in patients with breast cancer based on the mCAF signature genes

Shen, H.; Huang, B.; Chen, Q.; Ye, Z.; Zeng, L.; Huang, C.; Xie, Y.; Zhang, R.

10.1101/2023.06.08.544261 — genomics — Posted on 2023-06-11

2966 The Genetic Heterogeneity of Multimodal Human Brain Age

Wen, J.; Zhao, B.; Yang, Z.; Erus, G.; Skampardoni, I.; Mamourian, E.; Cui, Y.; Hwang, G.; Bao, J.; Boquet-Pujadas, A.; Zhou, Z.; Veturi, Y.; Ritchie, M. D.; Thompson, P.; Shou, H.; Shen, L.; Toga, A. W.; Davatzikos, C.

10.1101/2023.04.13.536818 — genetics — Posted on 2023-06-11

2967 CHPF boosts proliferation and invasion of clear cell renal cell carcinoma

Zhang, Y.; Li, X.; Ran, S.; Deng, J.; Huang, Y.; Zhou, T.; Wang, Q.; Liu, J.; Zhang, Q.; Li, X.; Leng, T.; Luo, Y.; Zhao, Y.; Li, S.

10.1101/2023.06.09.544296 — genetics — Posted on 2023-06-11

2968 Decreased inter-hemispheric connectivity predicts a coherent retrieval of auditory symbolic material in a laboratory model of cultural transmission

Bonetti, L.; Vaenggard, A. K.; Iorio, C.; Vuust, P.; Lumaca, M.

10.1101/2023.06.07.543882 — neuroscience — Posted on 2023-06-11

2969 Dopamine alters the effect of brain stimulation on decision-making

Leow, L.-A.; Marcos, A.; Nielsen, E.; Sewell, D. K.; Ballard, T.; Dux, P. E.; Filmer, H. L.

10.1101/2023.06.05.543812 — neuroscience — Posted on 2023-06-11

2970 Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse

Kurt, Z.; Cheng, J.; McQuillen, C. N.; Saleem, Z.; Hsu, N.; Jiang, N.; Barrere-Cain, R.; Pan, C.; Franzen, O.; Koplev, S.; Wang, S.; Bjorkegren, J.; Lusis, A. J.; Blencowe, M.; Yang, X.

10.1101/2023.06.08.544148 — systems biology — Posted on 2023-06-11

2971 Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine

Valega-Mackenzie, W.; Rodriguez Messan, M.; Yogurtcu, O. N.; Nukala, U.; Sauna, Z. E.; Yang, H.

10.1101/2023.06.09.544293 — systems biology — Posted on 2023-06-11

2972 Autoencoder Model for Translating Omics Signatures

Meimetis, N.; Pullen, K. M.; Zhu, D. Y.; Hoang, T. N.; Magliacane, S.; Lauffenburger, D. A.

10.1101/2023.06.08.544243 — bioinformatics — Posted on 2023-06-11

2973 Novel topological methods for identifying surprising protein tertiary structure relationships.

Bale, A.; Rambo, R.; Prior, C.

10.1101/2023.06.09.544297 — bioinformatics — Posted on 2023-06-11

2974 Thin Microfluidic Chips with Active Valves

Prajapati, E.; Giri, P. S.; Rath, S. N.; Kumar, S.

10.1101/2023.06.09.544232 — bioengineering — Posted on 2023-06-11

2975 Substantial variation in species ages among vertebrate clades

Pie, M. R.; Caron, F.

10.1101/2023.06.08.544238 — evolutionary biology — Posted on 2023-06-11

2976 Modelling the probability of meeting IUCN Red List criteria to support reassessments.

Henry, E. G.; Santini, L.; Butchart, S.; Gonzalez-Suarez, M.; Lucas, P. M.; Benitez-Lopez, A.; Mancini, G.; Jung, M.; Cardoso, P.; Zizka, A.; Meyer, C.; Akcakaya, H. R.; Berryman, A.; Cazalis, V.; Di Marco, M.

10.1101/2023.06.08.544254 — ecology — Posted on 2023-06-11

2977 Peripheral direct current for suppression of physiologically evoked nociceptive responses at the spinal cord

Su, T. F.; Hamilton, J. D.; Guo, Y.; Potas, J. R.; Shivdasani, M. N.; Moalem-Taylor, G.; Fridman, G. Y.; Aplin, F. P.

10.1101/2023.06.07.544048 — neuroscience — Posted on 2023-06-11

2978 Quantifying and predicting chromatic thresholds

Zhou, J.

10.1101/2023.06.06.543898 — neuroscience — Posted on 2023-06-11

2979 Combined effects of P25 TiO2 nanoparticles and disposable face mask leachate on microalgae Scenedesmus obliquus: Analysing the effects of heavy metals

Das, S.; Mukherjee, A.

10.1101/2023.06.08.544143 — pharmacology and toxicology — Posted on 2023-06-11

2980 Intra-lineage microevolution of Wolbachia leads to the emergence of new cytoplasmic incompatibility patterns

Namias, A.; Ngaku, A.; Makoundou, P.; Unal, S.; Sicard, M.; Weill, M.

10.1101/2023.06.08.544196 — evolutionary biology — Posted on 2023-06-11

2981 Intraspecific scaling of home range size and its bioenergetic dependence

Byrnes, E. E.; Hounslow, J. L.; Heim, V.; White, C. E.; Smukall, M. J.; Beatty, S. J.; Gleiss, A. C.

10.1101/2023.06.08.544203 — ecology — Posted on 2023-06-11

2982 A Simulation Study on High Spatio-Temporal Resolution Acousto-Electrophysiological Neuroimaging

Schoeters, R.; Tarnaud, T.; Martens, L.; Tanghe, E.

10.1101/2023.06.07.544012 — neuroscience — Posted on 2023-06-11

2983 Neuronal Activation of the Gαq Protein EGL-30/GNAQ Late in Life Rejuvenates Cognition Across Species

Stevenson, M. E.; Bieri, G.; Kaletsky, R.; Ange, J. S.; Remesal, L.; Pratt, K. J. B.; Zhou, S.; Weng, Y.; Murphy, C. T.; Villeda, S. A.

10.1101/2023.06.06.543909 — neuroscience — Posted on 2023-06-11

2984 Phosphoprotein dynamics of interacting tumor and T cells by HySic

Ibanez-Molero, S.; Pruijs, J.; Atmopawiro, A.; Wang, F.; Altelaar, M. E.; Peeper, D. S.; Stecker, K. E.

10.1101/2023.06.05.541905 — cancer biology — Posted on 2023-06-11

2985 A Bayesian observer model reveals a prior for natural daylights in hue perception

Su, Y.; Shi, Z.; Wachtler, T.

10.1101/2023.06.06.543889 — neuroscience — Posted on 2023-06-11

2986 Local and Global Measures of Information Storage for the Assessment of Heartbeat-Evoked Cortical Responses

Bara, C.; Zaccaro, A.; Antonacci, Y.; Riva, M. D.; Busacca, A.; Ferri, F.; Faes, L.; Pernice, R.

10.1101/2023.06.07.544078 — neuroscience — Posted on 2023-06-11

2987 Determinants of hyena participation in risky collective action

Montgomery, T. M.; Lehmann, K. D. S.; Gregg, S.; Keyser, K.; McTigue, L. E.; Beehner, J. C.; Holekamp, K. E.

10.1101/2022.05.30.494003 — animal behavior and cognition — Posted on 2023-06-11

2988 LINKIN-associated proteins necessary for tissue integrity during collective cell migration

Tan, C.-H.; Cheng, K.-W.; Park, H.; Sternberg, P. W.; Chou, T.-F.

10.1101/2023.02.08.527750 — developmental biology — Posted on 2023-06-11

2989 Impaired lamin localization to the nuclear envelope is responsible for nuclear damage in LMNA mutant iPSC-derived cardiomyocytes

Wallace, M.; Zahr, H.; Perati, S.; Morsink, C. D.; Johnson, L. E.; Gacita, A. M.; Lai, S.; Wallrath, L. L.; Benjamin, I. J.; McNally, E.; Kirby, T. J.; Lammerding, J.

10.1101/2021.10.30.466591 — cell biology — Posted on 2023-06-11

2990 Single-cell Bayesian deconvolution

Torregrosa, G.; Oriola, D.; Trivedi, V.; Garcia-Ojalvo, J.

10.1101/2022.02.13.480250 — systems biology — Posted on 2023-06-11

2991 Straining the root on and off triggers local calcium signaling

Audemar, V.; Guerringue, Y.; Frederick, J.; Melogno, I.; Vinet, P.; Babataheri, A.; Legue;, V.; Thomine, S.; Frachisse, J.-M.

10.1101/2023.05.11.540308 — plant biology — Posted on 2023-06-11

2992 Determinants of hyena participation in risky collective action

Montgomery, T. M.; Lehmann, K. D. S.; Gregg, S.; Keyser, K.; McTigue, L. E.; Beehner, J. C.; Holekamp, K. E.

10.1101/2022.05.30.494003 — animal behavior and cognition — Posted on 2023-06-11

2993 Nuclei function as wedges to pry open spaces and promotecollective, confined cell migration in vivo

Penfield, L.; Montell, D.

10.1101/2021.12.16.473064 — cell biology — Posted on 2023-06-11

2994 Trained immunity in human monocyte enhances myeloid-T-cell pathogenic crosstalk in Ankylosing Spondylitis

Zhao, J.; Liu, F.; Worth, C.; Simone, D.; Penkava, F.; Shi, H.; Li, J.; Lama, S.; Fang, H.; Lee, J. S.; Kim, T.-J.; Duan, L.; Bowness, P.; Chen, L.

10.1101/2023.06.10.544264 — molecular biology — Posted on 2023-06-10

2995 Roadmap for Canonical and Extended Endocannabinoid System Receptors in Peripheral Organs of Preclinical Animal Models

Rosado-Franco, J. J.; Ellison, A. L.; White, C. J.; Price, A. S.; Moore, C. F.; Williams, R. E.; Fridman, L. B.; Weerts, E. M.; Williams, D. W.

10.1101/2023.06.10.544455 — molecular biology — Posted on 2023-06-10

2996 Glucocorticoid stress hormones stimulate vesicle-free Tau secretion and spreading in the brain

Yu, Q.; Du, F.; Belli, I.; Gomes, P. A.; Sotiropoulos, I.; Waites, C. L.

10.1101/2023.06.07.544054 — neuroscience — Posted on 2023-06-10

2997 Biological embedding of childhood adversity - a multi-omics perspective on stress regulation

Zang, J. C. S.; May, C.; Marcus, K.; Kumsta, R.

10.1101/2023.06.10.544462 — systems biology — Posted on 2023-06-10

2998 Alteration of DNMT1/DNMT3A by eribulin elicits global DNA methylationchanges with potential therapeutic implications for triple-negative breastcancer

Bagheri, M.; Lee, M. K.; Muller, K. E.; Miller, T. W.; Pattabiraman, D. R.; Christensen, B. C.

10.1101/2023.06.09.544426 — cancer biology — Posted on 2023-06-10

2999 RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma

Randolph, M. E.; Afifi, M.; Gorthi, A.; Weil, R.; Wilky, B. A.; Weinreb, J.; Ciero, P.; ter Hoeve, N.; van Diest, P. J.; Raman, V.; Bishop, A. J.; Loeb, D. M.

10.1101/2023.06.10.544474 — cancer biology — Posted on 2023-06-10

3000 Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters

Park, Y.; Hernandez, S.; Hernandez, C. O.; Schweiger, H. E.; Li, H.; Voitiuk, K.; Dechiraju, H.; Hawthorne, N.; Muzzy, E. M.; Selberg, J. A.; Sullivan, F. N.; Urcuyo, R.; Salama, S. R.; Aslankoohi, E.; Teodorescu, M.; Mostajo-Radji, M. A.; Rolandi, M.

10.1101/2023.06.10.544416 — bioengineering — Posted on 2023-06-10

3001 Excitatory neurons derived from human induced Pluripotent Stem Cells show transcriptomic differences in Alzheimers patients from controls

Sagar, R.; Azoidis, I.; Zivko, C.; Xydia, A.; Oh, E.; Rosenberg, P. B.; Lyketsos, C. G.; Mahairaki, V.; Avramopoulos, D.

10.1101/2023.06.10.544465 — genetics — Posted on 2023-06-10

3002 Paradoxical anti-arrhythmic effects of Zim3, a CRISPRi effector, in human iPSC-cardiomyocytes

Han, J. L.; Heinson, Y. W.; Entcheva, E.

10.1101/2023.06.10.544468 — molecular biology — Posted on 2023-06-10

3003 A 2-million-year-old microbial and viral communities from the Kap Kobenhavn Formation in North Greenland

Fernandez-Guerra, A.; Borrel, G.; Delmont, T. O.; Elberling, B.; Eren, A. M.; Gribaldo, S.; Jochheim, A.; Henriksen, R. A.; Hinrichs, K.-U.; Korneliussen, T. S.; Krupovic, M.; Larsen, N. K.; Perez-Laso, R.; Pedersen, M. W.; Pedersen, V. K.; Sand, K. K.; Sikora, M.; Steinegger, M.; Veseli, I. A.; Wörmer, L.; Zhao, L.; Zure, M.; Kjaer, K. H.; Willerslev, E.

10.1101/2023.06.10.544454 — microbiology — Posted on 2023-06-10

3004 The displacement of the σ70 finger in initial transcription is highly heterogeneous and promoter-dependent

Wang, A.; MAZUMDER, A.; Kapanidis, A.

10.1101/2023.06.10.544452 — biophysics — Posted on 2023-06-10

3005 Structural basis of CMKLR1 signaling induced by chemerin9

Zhang, C.; Zhang, X.; Weiss, T.; Cheng, M. H.; Chen, S.; Ambrosius, C. K.; Czerniak, A. S.; Li, K.; Feng, M.; Bahar, I.; Beck-Sickinger, A. G.

10.1101/2023.06.09.544295 — biophysics — Posted on 2023-06-10

3006 African Swine Fever Virus major capsid p72 Trimers function as a pH sensor during uncoating process of virus endocytosis

Meng, K.; Huyan, Y.; Liu, Q.; Li, J.; Xiang, Y.; Meng, G.

10.1101/2023.06.09.544430 — microbiology — Posted on 2023-06-10

3007 Microbiome Features Associated with Performance Measures in Non-Athletic and Athletic Individuals

Huminska-Lisowska, K.; Zielinska, K.; Mieszkowski, J.; Michalowska-Sawczyn, M.; Cieszczyk, P.; Labaj, P. P.; Wasag, B.; Fraczek, B.; Grzywacz, A.; Kochanowicz, A.; Kosciolek, T.

10.1101/2023.06.10.544446 — microbiology — Posted on 2023-06-10

3008 KIF1A neurodegenerative disease mutations modulate motor motility and force generation

Shewale, D. J.; Soppina, P.; Soppina, V.

10.1101/2023.06.09.544228 — biophysics — Posted on 2023-06-10

3009 Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokes

Gennerich, A.; Liu, X.; Rao, L.; Qiu, W.

10.1101/2023.06.09.544415 — biophysics — Posted on 2023-06-10

3010 Machine Learning to Predict Continuous Protein Properties from Simple Binary Sorting and Deep Sequencing Data

Case, M.; Smith, M.; Vinh, J.; Thurber, G.

10.1101/2023.06.09.544229 — bioengineering — Posted on 2023-06-10

3011 Saturation Genome Editing Resolves the Functional Spectrum of Pathogenic VHL Alleles

Buckley, M.; Kajba, C. M.; Forrester, N. M.; Terwagne, C.; Sawyer, C.; Shepherd, S. T. C.; De Jonghe, J.; Dace, P.; Turajlic, S.; Findlay, G. M.

10.1101/2023.06.10.542698 — genomics — Posted on 2023-06-10

3012 Differences in the transcriptome response in the gills of sea lamprey acutely exposed to 3-trifluoromethyl-4-nitrophenol (TFM), niclosamide or a TFM:niclosamide mixture

Lawrence, M. J.; Grayson, P. J.; Jeffrey, J.; Docker, M.; Garroway, C. J.; Wilson, J.; Manzon, R.; Wilkie, M.; Jeffries, K.

10.1101/2023.06.08.544220 — genomics — Posted on 2023-06-10

3013 Cochlear transcriptome analysis of an outbred mouse population (CFW)

Boussaty, E. C.; Tedeschi, N.; Novotny, M.; Ninoyu, Y.; Du, E.; Draf, C.; Zhang, Y.; Manor, U.; Scheuermann, R. H.; Friedman, R. A.

10.1101/2023.02.15.528661 — genomics — Posted on 2023-06-10

3014 Rapid Adaption of Cellular Metabolic Rate to the microRNA Complements of Mammals

Fromm, B.; Sorger, T.

10.1101/2022.11.24.517858 — evolutionary biology — Posted on 2023-06-10

3015 CLOCK evolved in cnidaria to synchronize internal rhythms with circadian environmental cues

Rinsky, M.; Aguillon, R.; Simon-Blecher, N.; Doniger, T.; Appelbaum, L.; Levy, O.

10.1101/2023.03.30.534918 — evolutionary biology — Posted on 2023-06-10

3016 Innovative approach for vaccinating Nile tilapia, Oreochromis niloticus against Streptococcus agalactiae using an ozone nanobubble pre-treatment, VAC in BAG and VAC in FEED

Vinh, N. T.; Dong, H. T.; Senapin, S.; Pumpuang, S.; Lan, N. G. T.; Wilairat, B.; Garud, P. R.; St-Hilaire, S.; Linh, N. V.; Phanphut, W.; Shinn, A. P.

10.1101/2023.06.09.544435 — immunology — Posted on 2023-06-10

3017 An efficient behavioral screening platform classifies natural products and other chemical cues according to their chemosensory valence in C. elegans

Fryer, E.; Guha, S.; Rogel-Hernandez, L. E.; Logan-Garbisch, T.; Farah, H.; Molhoff, I. N.; Rezaei, E.; Nekimken, A. L.; Xu, A.; Fechner, S.; Druckman, S.; Clandinin, T. R.; Rhee, S. Y.; Goodman, M. B.

10.1101/2023.06.02.542933 — neuroscience — Posted on 2023-06-10

3018 Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations

Solis, E. M.; Good, L. B.; Vazquez, R. G.; Patnaik, S.; Hernandez-Reynoso, A. G.; Ma, Q.; Angulo, G.; Dobariya, A.; Cogan, S. F.; Pancrazio, J. J.; Pascual, J. M.; Jakkamsetti, V.

10.1101/2023.06.05.543611 — neuroscience — Posted on 2023-06-10

3019 A calibration and uncertainty quantification analysis of classical, fractional and multiscale logistic models of tumour growth

Dimitriou, N. M.; Demirag, E.; Strati, K.; Mitsis, G. D.

10.1101/2023.04.12.536622 — systems biology — Posted on 2023-06-10

3020 Information-theoretic analysis of a model of CAR-4-1BB-mediated NFκB activation

Tserunyan, V.; Finley, S. D.

10.1101/2023.06.09.544433 — systems biology — Posted on 2023-06-10

3021 Post-acquisition super resolution for cryo-electron microscopy

Burton-Smith, R. N.; Murata, K.

10.1101/2023.06.09.544325 — biophysics — Posted on 2023-06-10

3022 Liquid-liquid phase separation and aggregation of a globular folded protein SUMO1

Arora, S.; Saha Roy, D.; Maiti, S.; Ainavarapu, S. R. K.

10.1101/2023.06.10.544456 — biophysics — Posted on 2023-06-10

3023 Body-wide landscape of cell type-specific total cellular transcriptome-size and its physiological significance

Tejima, K.; Kozawa, S.; Sato, T. N.

10.1101/2020.07.05.188276 — bioinformatics — Posted on 2023-06-10

3024 Plasmodium falciparum transmission in the highlands of Ethiopia is driven by closely related and clonal parasites

Holzschuh, A.; Ewnetu, Y.; Carlier, L.; Lerch, A.; Gerlovina, I.; Baker, S. C.; Yewhalaw, D.; Berhane, N.; Lemma, W.; Koepfli, C.

10.1101/2023.06.09.544365 — genomics — Posted on 2023-06-10

3025 Sea anemone genomes reveal ancestral metazoan chromosomal macrosynteny

Zimmermann, B.; Montenegro, J. D.; Robb, S. M. C.; Fropf, W. J.; Weilguny, L.; He, S.; Chen, S.; Lovegrove-Walsh, J.; Hill, E. M.; Chen, C.-Y.; Ragkousi, K.; Praher, D.; Fredman, D.; Schultz, D. T.; Moran, Y.; Simakov, O.; Genikhovich, G.; Gibson, M. C.; Technau, U.

10.1101/2020.10.30.359448 — genomics — Posted on 2023-06-10

3026 Profiling The Compendium Of Changes In Saccharomyces cerevisiae Due To Mutations That Alter Availability Of The Main Methyl Donor S-Adenosylmethionine

Remines, M.; Schnoover, M.; Zoey, K.; Kailee, K.; Hoffert, K. M.; Coric, A.; Mead, J.; Ampfer, J.; Seye, S.; Strome, E.

10.1101/2023.06.09.544294 — genetics — Posted on 2023-06-10

3027 Diet influences resource allocation in chemical defence but not melanin synthesis in an aposematic moth

Ottocento, C.; Rojas, B.; Burdfield-Steel, E.; Furlanetto, M.; Nokelainen, O.; Winters, S.; Mappes, J.

10.1101/2023.02.24.529866 — ecology — Posted on 2023-06-10

3028 LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility

Hwang, J. Y.; Chai, P.; Nawaz, S.; Choi, J.; Lopez-Giraldez, F.; Hussain, S.; Bilguvar, K.; Mane, S.; Lifton, R. P.; Ahmad, W.; Zhang, K.; Chung, J.-J.

10.1101/2023.02.25.530050 — cell biology — Posted on 2023-06-10

3029 mRNA vaccine induces protective immunity against the type III secretory virulence of Pseudomonas aeruginosa

Kawaguchi, K.; Kinoshita, M.; Sudo, K.; Inoue, K.; Naito, Y.; Oba, M.; Uchida, S.; Sawa, T.

10.1101/2023.06.09.544431 — immunology — Posted on 2023-06-10

3030 Identification of tumor-specific MHC ligands through improved biochemical isolation and incorporation of machine learning

Mecklenbräuker, S.; Skoczylas, P.; Biernat, P.; Zaghla, B.; Krol-Jozaga, B.; Jasinski, M.; Murcia Pienkowski, V.; Sanecka-Duin, A.; Popp, O.; Szatanek, R.; Mertins, P.; Kaczmarczyk, J.; Blum, A.; Klatt, M. G.

10.1101/2023.06.08.544182 — immunology — Posted on 2023-06-10

3031 Repurposing The Dark Genome. III - Intronic Proteins

Garg, M.; Dhar, P. K.

10.1101/2023.06.10.544447 — synthetic biology — Posted on 2023-06-10

3032 Mag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome

Wu, C. C.; Tsantilas, K. J.; Park, J.; Plubell, D. L.; Naicker, P.; Govender, I.; Buthelezi, S.; Stoychev, S.; Jordaan, J.; Merrihew, G. E. E.; Huang, E.; Parker, E. D.; Riffle, M.; Hoofnagle, A. N.; MacCoss, M. J.

10.1101/2023.06.10.544439 — biochemistry — Posted on 2023-06-10

3033 eIF4E1b is a non-canonical eIF4E required for maternal mRNA dormancy

Lorenzo-Orts, L.; Strobl, M.; Steinmetz, B.; Leesch, F.; Pribitzer, C.; Schutzbier, M.; Duernberger, G.; Pauli, A.

10.1101/2023.06.10.544440 — developmental biology — Posted on 2023-06-10

3034 NMR structure verifies the eponymous degenerate zinc finger domain of transcription factor ZNF750

Rua, A. J.; Whitehead, R. D.; Alexandrescu, A. T.

10.1101/2023.06.10.544471 — molecular biology — Posted on 2023-06-10

3035 Structure of the N-RNA/P interface reveals mode of L/P attachment to the nucleocapsid of human metapneumovirus

Whitehead, J. D.; Decool, H.; Leyrat, C.; Carrique, L.; Fix, J.; Eleouet, J.-F.; Galloux, M.; Renner, M.

10.1101/2023.06.10.544460 — microbiology — Posted on 2023-06-10

3036 Senescent Subtypes Transition Model

Singh, G.

10.1101/2023.06.10.544466 — systems biology — Posted on 2023-06-10

3037 An exosome-based gene delivery platform for cell-specific CRISPR/Cas9 genome editing

Dubey, S.; Chen, Z.; Talis, A.; Molotkov, A.; Ali, A.; Mintz, A.; Momen-Heravi, F.

10.1101/2023.06.09.542202 — molecular biology — Posted on 2023-06-09

3038 Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration

Lee, S.; Vander Roest, A. S.; Blair, C.; Kao, K.; Bremner, S. B.; Childers, M. C.; Pathak, D.; Heinrich, P.; Lee, D.; Chirikian, O.; Mohran, S.; Roberts, B.; Smith, J. E.; Jahng, J. W. S.; Paik, D. T.; Wu, J. C.; Gunawardane, R. N.; Spudich, J. A.; Ruppel, K. M.; Mack, D.; Pruitt, B. L.; Regnier, M.; Wu, S. M.; Bernstein, D.

10.1101/2023.06.08.544276 — molecular biology — Posted on 2023-06-09

3039 An efficient stochastic steering strategy of magnetic particles in vascular networks

Chen, K.; Zhou, R.; Dong, X.

10.1101/2023.02.23.529635 — biophysics — Posted on 2023-06-10

3040 3D spheroid culturing of Astyanax mexicanus liver-derived cell lines recapitulates distinct transcriptomic and metabolic states of in vivo tissue environment.

Biswas, T.; Rajendran, N.; Hassan, H.; Zhao, C.; Rohner, N.

10.1101/2023.06.09.544423 — evolutionary biology — Posted on 2023-06-10

3041 Allelic chromatin structure primes imprinted expression of Kcnk9 during neurogenesis

Loftus, D.; Bae, B.; Whilden, C. M.; Whipple, A. J.

10.1101/2023.06.09.544389 — molecular biology — Posted on 2023-06-09

3042 Optimisation of sample preparation from primary mouse tissue to maintain RNA integrity for methods examining translational control

Munro, J.; Gillen, S. L.; Mitchell, L.; Laing, S.; Karim, S. A.; Rink, C.; Waldron, J. A.; Bushell, M.

10.1101/2023.06.09.544315 — molecular biology — Posted on 2023-06-09

3043 IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells

Fischer, S.; Weber, L. M.; Stielow, B.; Frech, M.; Simon, C.; Koennecke, J.; Forne, I.; Nist, A.; Bauer, U.-M.; Stiewe, T.; Neubauer, A.; Liefke, R.

10.1101/2023.06.09.544165 — molecular biology — Posted on 2023-06-09

3044 HNF4a regulates acyl chain remodeling and ether lipid accumulation in hepatic steatosis

Von Bank, H.; Geoghegan, G.; Jain, R.; Kotulkar, M.; Hurtado-Thiele, M.; Gonzalez, P.; Kirsh, C.; Chevalier, A.; Schueler, K. L.; Attie, A. D.; Keller, M. P.; Apte, U.; Simcox, J.

10.1101/2023.06.08.544272 — molecular biology — Posted on 2023-06-09

3045 TidyTron: Reducing lab waste using validated wash-and-reuse protocols for common plasticware in Opentrons OT-2 lab robots

Bryant, J. A.; Longmire, C.; Sridhar, S.; Janousek, S.; Kellinger, M.; Wright, R. C.

10.1101/2023.06.09.544400 — molecular biology — Posted on 2023-06-09

3046 A Cost-Effective CRISPR/Cas9-Based Method for Sequencing the Functional Antibody Kappa Chain cDNA from Hybridomas Expressing Aberrant Kappa Chain mRNAs

Ahnoud, A.; He, C.; Strainic, M.; Zhai, W.

10.1101/2023.06.08.544271 — molecular biology — Posted on 2023-06-09

3047 The chromatin landscape of healthy and injured cell types in the human kidney

Gisch, D. L.; Brennan, M.; Lake, B. B.; Basta, J.; Keller, M.; Melo Ferreira, R.; Akilesh, S.; Ghag, R.; Lu, C.; Cheng, Y.-H.; Collins, K. S.; Parikh, S. V.; Rovin, B. H.; Robbins, L.; Conklin, K. Y.; Diep, D.; Zhang, B.; Knoten, A.; Barwinska, D.; Asghari, M.; Sabo, A. R.; Ferkowicz, M. J.; Sutton, T. A.; Kelly, K. J.; De Boer, I. H.; Rosas, S. E.; Kiryluk, K.; Hodgin, J. B.; Alakwaa, F.; Jefferson, N.; Gaut, J. P.; Gehlenborg, N.; Phillips, C. L.; El-Achkar, T. M.; Dagher, P. C.; Hato, T.; Zhang, K.; Himmelfarb, J.; Kretzler, M.; Mollah, S.; Kidney Precision Medicine Project, ; Jain, S.; Ra

10.1101/2023.06.07.543965 — molecular biology — Posted on 2023-06-10

3048 2',3' cyclic-nucleotide 3'-phosphodiesterase (CNP) inhibits SARS-CoV-2 virion assembly by blocking infection-induced mitochondria depolarization

Logue, J.; Melville, V.; Ardanuy, J.; Frieman, M.

10.1101/2023.06.09.544327 — microbiology — Posted on 2023-06-09

3049 Innate immune responses yield tissue-specific bottlenecks that scale with pathogen dose

Hullahalli, K.; Dailey, K. G.; Waldor, M. K.

10.1101/2023.06.09.543079 — microbiology — Posted on 2023-06-09

3050 Enhancing the antibacterial function of probiotic Escherichia coli Nissle: when less is more

Bartram, E.; Asai, M.; Gabant, P.; Wigneshweraraj, R.

10.1101/2023.06.09.544192 — microbiology — Posted on 2023-06-09

3051 Spatial Mapping of Mobile Genetic Elements and their Cognate Hosts in Complex Microbiomes

Grodner, B.; Shi, H.; Farchione, O.; Vill, A. C.; Ntekas, I.; Diebold, P. J.; Zipfel, W. R.; Brito, I. L.; De Vlaminck, I.

10.1101/2023.06.09.544291 — microbiology — Posted on 2023-06-09

3052 Pontiella agarivorans sp. nov., a novel marine anaerobic bacterium capable of degrading macroalgal polysaccharides and fixing nitrogen

Liu, N.; Kivenson, V.; Peng, X.; Cui, Z.; Lankiewicz, T.; Gosselin, K. M.; O'Malley, M. A.; Valentine, D. L.

10.1101/2023.06.09.544357 — microbiology — Posted on 2023-06-09

3053 A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth

Tomasi, F. G.; Kimura, S.; Rubin, E. J.; Waldor, M. K.

10.1101/2023.02.20.529267 — microbiology — Posted on 2023-06-09

3054 Inhibition of OCT4 Binding at the MYCN Locus Induces Neuroblastoma Cell Death Accompanied by Downregulation of Transcripts with High-Open Reading Frame Dominance

Nakatani, K.; Kogashi, H.; Miyamoto, T.; Setoguchi, T.; Sakuma, T.; Kugou, K.; Hasegawa, Y.; Yamamoto, T.; Hippo, Y.; Suenaga, Y.

10.1101/2023.06.08.544289 — cancer biology — Posted on 2023-06-10

3055 Structural basis of the interaction between ESV1 and LESV from Arabidopsis thaliana with starch glucans.

Osman, R.; Bossu, M.; Dauvillee, D.; Spriet, C.; Liu, C.; Zeeman, S. C.; D'Hulst, C.; Bompard, C.

10.1101/2023.06.09.544376 — biophysics — Posted on 2023-06-10

3056 De novo design of a β-helix tau protein scaffold: An oligomer-selective vaccine immunogen candidate for Alzheimer's disease

Aina, A.; Hsueh, S. C. C.; Gibbs, E.; Peng, X.; Cashman, N. R.; Plotkin, S. S.

10.1101/2023.06.08.544248 — bioengineering — Posted on 2023-06-10

3057 Genome analysis of Legionella pneumophila ST901 an Italian endemic strain.

Ricci, M. L.; Fillo, S.; Giordani, F.; Ciammaruconi, A.; Girolamo, A.; Anselmo, A.; Monte, A.; Cusimano, V.; Caporali, M. G.; Rota, M. C.; Petzol, M.; Afshar, B.; Lista, F.; Luck, C.; Scaturro, M.

10.1101/2023.06.08.544189 — genomics — Posted on 2023-06-10

3058 Diversity at single nucleotide to pangenome scales among sulfur cycling bacteria in salt marshes

Perez Castro, S.; Peredo, E. L.; Mason, O.; Vineis, J. H.; Bowen, J. L.; Mortazavi, B.; Ganesh, A.; Ruff, S. E.; Paul, B. G.; Giblin, A.; Cardon, Z.

10.1101/2023.06.08.544202 — ecology — Posted on 2023-06-10

3059 Low-troposphere microbial communities differ between dry-air and rainfall but do not show strong seasonal patterns in Metro Atlanta, Southeast USA

Davila-Santiago, L.; Erb, C.; Yang, L. H.; Hall, J.; Negron, A.; D'amico, I.; Hatt, J.; Konstantinidis, K. T.

10.1101/2023.06.09.544356 — microbiology — Posted on 2023-06-09

3060 Acyl-AcpB, a FabT co-repressor in Streptococcus pyogenes

Lambert, C.; d'Orfani, A.; Gaillard, M.; Zhang, Q.; Gloux, K.; Poyart, C.; Fouet, A.

10.1101/2023.06.09.544320 — microbiology — Posted on 2023-06-09

3061 TDP-43-stratified single-cell proteomic profiling of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis

Guise, A. J.; Misal, S. A.; Carson, R.; Boekweg, H.; Van Der Watt, D.; Truong, T.; Liang, Y.; Chu, J.-H.; Welsh, N.; Gagnon, J.; Payne, S. H.; Plowey, E. D.; Kelly, R. T.

10.1101/2023.06.08.544233 — pathology — Posted on 2023-06-10

3062 Zea mays genotype influences microbial and viral rhizobiome community structure

Yadav, P.; Quattrone, A.; Yang, Y.; Owens, J.; Kiat, R.; Kuppusamy, T.; Russo, S. E.; Weber, K. A.

10.1101/2023.06.09.544353 — microbiology — Posted on 2023-06-09

3063 Type 4 pili mediated natural competence in Fusobacterium nucleatum

Sanders, B. E.; Umana, A.; Nguyen, T. T. D.; Williams, K. J.; Yoo, C. C.; Casasanta, M. A.; Wozniak, B.; Slade, D. J.

10.1101/2023.06.09.544391 — microbiology — Posted on 2023-06-09

3064 zol & fai: large-scale targeted detection and evolutionary investigation of gene clusters

Salamzade, R.; Tran, P. Q.; Martin, C.; Manson, A. L.; Gilmore, M. S.; Earl, A. M.; Anantharaman, K.; Kalan, L.

10.1101/2023.06.07.544063 — bioinformatics — Posted on 2023-06-10

3065 Montane rain forest dynamics under changes in climate and human impact during the past millennia in northern Madagascar

Montade, V.; Bremond, L.; Teixeira, H.; Kasper, T.; Daut, G.; Rasoamanana, E.; Ramavovolona, P.; Favier, C.; Arnaud, F.; Radespiel, U.; Behling, H.

10.1101/2023.06.07.544115 — ecology — Posted on 2023-06-10

3066 A trigger may not be necessary to cause senescence in deciduous broadleaf forests

Wheeler, K. I.; Dietze, M. C.

10.1101/2023.06.07.544057 — ecology — Posted on 2023-06-10

3067 Host Gastric Corpus Microenvironment Facilitates Ascaris Suum Larval Hatching And Infection in a Murine Model

WU, Y.; ADENIYI-IPADEOLA, G.; ADKINS-THREATS, M.; SEASOCK, M.; SUAREZ-REYES, C.; RICARDO, F.; BOTTAZZI, M. E.; SONG, L.; MILLS, J. C.; Weatherhead, J. E.

10.1101/2023.06.09.544412 — microbiology — Posted on 2023-06-09

3068 Myeloid-derived suppressor cells exacerbate poly(I:C)-induced lung inflammation in mice with renal injury and older mice

Xie, Z.; Zhou, H.; Obana, M.; Fujio, Y.; Okada, N.; Tachibana, M.

10.1101/2023.06.07.544030 — immunology — Posted on 2023-06-09

3069 Social navigation: distance and grid-like codes support navigation of abstract social space in the human brain

Liang, Z.; Wu, S.; Wu, J.; Wang, W.-X.; Qin, S.; Liu, C.

10.1101/2023.05.12.538784 — neuroscience — Posted on 2023-06-10

3070 Cross-reactivity of antibodies against T cell markers in the Bank vole (Myodes glareolus)

Migalska, M.; Weglarczyk, K.; Mezyk-Kopec, R.; Baliga-Klimczyk, K.; Homa, J.

10.1101/2023.06.07.544031 — immunology — Posted on 2023-06-09

3071 Fundamental role for the creatine kinase pathway in protection from murine colitis

Hall, C. H.; Lanis, J. M.; Dowdell, A. S.; Murphy, E. M.; Colgan, S. P.

10.1101/2023.06.07.544110 — immunology — Posted on 2023-06-09

3072 The renal capsule, a vibrant and adaptive cell environment of the kidney in homeostasis and aging

Korin, B.; Avraham, S.; Moncada, R.; Ho, T.; Tleugabulova, M. C.; Menon, H.; Darmanis, S.; Liang, Y.; Modrusan, Z.; Chalouni, C.; Victoria, C.; Rangell, L.; Havnar, C.; Ewart, W.; Jones, C.; Jiang, J.; Dunlap, D.; Dohse, M.; McKay, A.; Webster, J. D.; Durinck, S.; Shaw, A. S.

10.1101/2023.05.11.540033 — immunology — Posted on 2023-06-09

3073 CXCR4 blockade alleviates pulmonary and cardiac outcomes in young COPD

Dupin, I.; Henrot, P.; Maurat, E.; Abohalaka, R.; Chaigne, S.; El Hamrani, D.; Eyraud, E.; Prevel, R.; Esteves, P.; Campagnac, M.; Dubreuil, M.; Cardouat, G.; Bouchet, C.; Ousova, O.; Dupuy, J.-W.; Trian, T.; Thumerel, M.; Begueret, H.; Girodet, P.-O.; Martan, R.; Zysman, M.; Michel, V.; Berger, P.

10.1101/2023.03.10.529743 — pathology — Posted on 2023-06-10

3074 Overburdened Ferroptotic Stress Impairs Tooth Morphogenesis

Wang, H.; Wang, X.; Wang, C.; Yu, F.; Ye, L.

10.1101/2023.06.08.544273 — developmental biology — Posted on 2023-06-10

3075 Enteric glial hub cells coordinate intestinal motility

Scavuzzo, M. A.; Letai, K. C.; Maeno-Hikichi, Y.; Wulftange, W. J.; Shah, I. K.; Rameshbabu, J. S.; Tomar, A.; Shick, H. E.; Shah, A. K.; Xiong, Y.; Cohn, E. F.; Allan, K. C.; Tesar, P. J.

10.1101/2023.06.07.544052 — neuroscience — Posted on 2023-06-09

3076 Touch sensation requires the mechanically-gated ion channel Elkin1.

Chakrabarti, S.; Klich, J.; Khallaf, M.; Sanchez-Carranza, O.; Baran, Z. M.; Rossi, A.; Huang, A. T.-L.; Pohl, T.; Fleischer, R.; Fuerst, C.; Hammes, A.; Begay, V.; Hornberg, H.; Poole, K.; Lewin, G. R.

10.1101/2023.06.09.544247 — neuroscience — Posted on 2023-06-09

3077 Pentose Phosphate Pathway Inhibition activates Macrophages towards phagocytic Lymphoma Cell Clearance

Beielstein, A. C.; Izquierdo, E.; Blakemore, S. J.; Nickel, N.; Michalik, M.; Chawan, S.; Brinker, R.; Bartel, H.-H.; Vorholt, D.; Nolte, J. L.; Linke, R.; Costa Picosi, C. R.; Saiz, J.; Picard, F.; Meinel, J.; Buettner, R.; Villasenor, A.; Winkels, H.; Hallek, M.; Krueger, M.; Barbas, C.; Pallasch, C. P.

10.1101/2023.06.09.543574 — cancer biology — Posted on 2023-06-09

3078 Single-cell analysis reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of ovarian cancer

Zhang, L.; Cascio, S.; ellors, J. W.; Buckanovich, R. J.; Osmanbeyoglu, H. U.

10.1101/2023.06.07.544095 — cancer biology — Posted on 2023-06-09

3079 A translational rodent model of individual differences in sensitivity to the aversive properties of ethanol

Przybysz, K. R.; Ramirez, L. A.; Pitock, J. R.; Starr, E. M.; Yang, H.; Glover, E. J.

10.1101/2023.06.08.544209 — neuroscience — Posted on 2023-06-09

3080 Updating the sulcal landscape of the human lateral parieto-occipital junction provides anatomical, functional, and cognitive insights

Willbrand, E. H.; Tsai, Y.-H.; Gagnant, T.; Weiner, K. S.

10.1101/2023.06.08.544284 — neuroscience — Posted on 2023-06-09

3081 Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis

Rentz, L. E.; Whetsell, M.; Clayton, S. A.; Mizner, A. D.; Holaskova, I.; Chapa, M. G.; Hoblitzell, E. H.; Eubank, T. D.; Pistilli, E. E.

10.1101/2023.06.07.544049 — cancer biology — Posted on 2023-06-09

3082 Brain Representations of Affective Valence and Intensity in Sustained Pleasure and Pain

Lee, S. A.; Lee, J.-J.; Han, J.; Choi, M. M.; Wager, T. D.; Woo, C.-W.

10.1101/2023.06.08.544230 — neuroscience — Posted on 2023-06-09

3083 Low-dose exposure to malathion and radiation culminates in the dysregulation of multiple neuronal processes instigating neurotoxicity and activation of neurodegeneration pathways in mice hippocampus

Narasimhamurthy, R. K.; Venkidesh, B. S.; Nayak, S.; Reghunathan, D.; Mallya, S.; Sharan, K.; Rao, B. S. S.; Mumbrekar, K. D.

10.1101/2023.06.08.544287 — neuroscience — Posted on 2023-06-09

3084 Combinatorial fedratinib and venetoclax treatment is effective on human B cell acute lymphoblastic leukemia with high Flt3 expression

Rinella, S. P.; Bell, H. C.; Turicek, D. P.; Shi, L.; Hoang, N.-M.; Rui, L.; Hess, N. J.; Capitini, C. M.

10.1101/2023.06.07.544058 — cancer biology — Posted on 2023-06-09

3085 Formation of Müller glia-derived progenitor cells in retinas depleted of microglia

El-Hodiri, H.; Bentley, J. R.; Reske, A. G.; Palazzo, I.; Campbell, W. A.; Halloy, N. R.; Fischer, A. J.

10.1101/2023.06.08.544205 — neuroscience — Posted on 2023-06-09

3086 In Silico Transcriptome-based Screens Identify Epidermal Growth Factor Receptor Inhibitors as Therapeutics for Noise-induced Hearing Loss

Vijayakumar, S.; DiGuiseppi, J. A.; Dabestani, J.; Ryan, W. G.; Vielman Quevedo, R.; Li, Y.; Diers, J.; Tu, S.; Fleegel, J. P.; Cassidy, N. M.; Rhoda, L. M.; Imami, A. S.; Hamoud, A. A.-R.; Lovas, S.; McCullumsmith, R.; Zallocchi, M.; Zuo, J.

10.1101/2023.06.07.544128 — neuroscience — Posted on 2023-06-09

3087 Light-induced condensates show accumulation-prone and less dynamic properties in the nucleus compared to the cytoplasm.

Hamada, Y.; Kitamura, A.

10.1101/2023.06.07.544154 — biophysics — Posted on 2023-06-09

3088 Speckle rheological spectroscopy reveals wideband viscoelastic spectra of biological tissues

Leartprapun, N.; Zeng, Z.; Hajjarian, Z.; Bossuyt, V.; Nadkarni, S. K.

10.1101/2023.06.08.544037 — biophysics — Posted on 2023-06-10

3089 Co-evolutionary dynamics of mammalian brain and body size

Venditti, C.; Baker, J.; Barton, R. A.

10.1101/2023.06.08.544206 — evolutionary biology — Posted on 2023-06-09

3090 Punishment resistance for cocaine is associated with inflexible habits in rats

Jones, B. O.; Paladino, M. S.; Cruz, A. M.; Spencer, H. F.; Kahanek, P. L.; Scarborough, L. N.; Georges, S. F.; Smith, R. J.

10.1101/2023.06.08.544242 — neuroscience — Posted on 2023-06-09

3091 3D analysis of dissection photographs with surface scanning and machine learning for quantitative neuropathology

Gazula, H.; Tregidgo, H.; Billot, B.; Balbastre, Y.; Williams-Ramirez, J.; Herisse, R.; Casamitjana, A.; Melief, E. J.; Latimer, C. S.; Kilgore, M. D.; Montine, M.; Robinson, E.; Blackburn, E.; Marshall, M. S.; Connors, T. R.; Oakley, D. H.; Frosh, M. P.; Van Leemput, K.; Dalca, A. V.; Fischl, B.; Mac Donald, C. L.; Keene, C. D.; Hyman, B.; Iglesias, J. E.

10.1101/2023.06.08.544050 — neuroscience — Posted on 2023-06-09

3092 A Practical Approach to Estimating the Effect of Synchrotron Radiation on Sperm Motility and Viability

Lindhoj, M. B.; Bonnin, A.; Almstrup, K.; Dyrby, T. B.; Mokso, R.; Sporring, J.

10.1101/2023.06.08.544169 — biophysics — Posted on 2023-06-09

3093 Robust Optogenetic Inhibition with Red-light-sensitive Anion-conducting Channelrhodopsins

Oppermann, J.; Rozenberg, A.; Fabrin, T.; GonzalezCabrera, C.; Beja, O.; Prigge, M.; Hegemann, P.

10.1101/2023.06.09.544329 — biophysics — Posted on 2023-06-09

3094 Swimming ability and flagellar motility of sperm packets of the volvocine green alga Pleodorina starrii

Kage, A.; Takahashi, K.; Nozaki, H.; Higashiyama, T.; Baba, S. A.; Nishizaka, T.

10.1101/2023.06.08.544266 — biophysics — Posted on 2023-06-09

3095 The genomic landscape of wild Saccharomyces cerevisiae is shaped by complex patterns of admixture, aneuploidy and recombination.

Ward, C. M.; Onetto, C. A.; Van Den Heuvel, S.; Cuijvers, K. M.; Hale, L. J.; Borneman, A. R.

10.1101/2023.06.07.544145 — genomics — Posted on 2023-06-09

3096 Two avian Plasmodium species trigger different transcriptional responses on their vector Culex pipiens

Garrigos, M.; Ylla, G.; Martinez-de la Puente, J.; Figuerola, J.; Ruiz-Lopez, M. J.

10.1101/2023.01.24.525339 — genomics — Posted on 2023-06-09

3097 Calling Cards: a customizable platform to longitudinally record protein-DNA interactions over time in cells and tissues

Yen, A.; Mateusiak, C.; Sarafinovska, S.; Gachechiladze, M. A.; Guo, J.; Chen, X.; Moudgil, A.; Cammack, A. J.; Hoisington-Lopez, J.; Crosby, M.; Brent, M.; Mitra, R. D.; Dougherty, J. D.

10.1101/2023.06.07.544098 — genomics — Posted on 2023-06-09

3098 The involvement of the human prefrontal cortex in the emergence of visual awareness

Fang, Z.; Dang, Y.; Ling, Z.; Han, Y.; Xu, X.; Zhao, H.; Zhang, M.

10.1101/2023.06.09.544290 — neuroscience — Posted on 2023-06-09

3099 Dopamine activation modulates oscillatory synchrony in the hippocampal-prefrontal cortex circuitry

de Oliveira Junior, B. A.; Leite, J. P.; Ruggiero, R. N.

10.1101/2023.06.07.544112 — neuroscience — Posted on 2023-06-09

3100 Structural Basis of σ54 Displacement and Promoter Escape in Bacterial Transcription

Gao, F.; Ye, F.; Zhang, B.; Cronin, N.; Buck, M.; Zhang, X.

10.1101/2023.06.09.544244 — biophysics — Posted on 2023-06-09

3101 Prediction of Heart Disease and Survivability using Support Vector Machine and Naive Bayes Algorithm

Patel, T. S.; Patel, D. P.; Sanyal, M.; Shrivastav, P. S.

10.1101/2023.06.09.543776 — bioinformatics — Posted on 2023-06-09

3102 Structural Characterization of the Full-length Hantaan Virus Polymerase

Keown, J. R.; Carrique, L.; Nilsson-payant, B.; Fodor, E.; Grimes, J. M.

10.1101/2023.06.09.544421 — biochemistry — Posted on 2023-06-09

3103 Hidden protein-altering variants influence diverse human phenotypes

Hujoel, M. L. A.; Handsaker, R. E.; Sherman, M. A.; Kamitaki, N.; Barton, A. R.; Mukamel, R. E.; Terao, C.; McCarroll, S.; Loh, P.-R.

10.1101/2023.06.07.544066 — genetics — Posted on 2023-06-09

3104 Detecting genetic effects on phenotype variability to capture gene-by-environment interactions: a systematic method comparison

Zhang, X.; Bell, J. T.

10.1101/2023.06.09.544298 — genetics — Posted on 2023-06-09

3105 Tonic Meningeal Interleukin-10 Upregulates Delta Opioid Receptor to Prevent Relapse to Pain

Inyang, K. E.; Sim, J.; Clark, K. B.; Matan, G.; Monahan, K.; Evans, C.; Beng, P.; Ma, J.; Heijnen, C. J.; Dantzer, R.; Scherrer, G.; Kavelaars, A.; Bernard, M.; Aldhamen, Y.; Folger, J. K.; Laumet, G.

10.1101/2023.06.08.544200 — neuroscience — Posted on 2023-06-09

3106 A non-oscillatory, millisecond-scale embedding of brain state provides insight into behavior.

Parks, D. F.; Schneider, A. M.; Xu, Y.; Brunwasser, S. J.; Funderburk, S.; Thurber, D.; Blanche, T.; Dyer, E. L.; Haussler, D.; Hengen, K. B.

10.1101/2023.06.09.544399 — neuroscience — Posted on 2023-06-09

3107 Molecular mechanisms reconstruction from single-cell multi-omics data with HuMMuS

Trimbour, R.; Deutschmann, I. M.; Cantini, L.

10.1101/2023.06.09.543828 — bioinformatics — Posted on 2023-06-09

3108 CViewer: A Java-based statistical framework for integration of shotgun metagenomics with other omics datasets

Koci, O.; Russell, R. K.; Sheikh, M. G.; Edwards, C.; Gerasimidis, K.; Ijaz, U. Z.

10.1101/2023.06.07.544017 — bioinformatics — Posted on 2023-06-09

3109 Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets

Koldobskiy, M. A.; Camacho, O.; Reddy, P.; Izpisua Belmonte, J. C.; Feinberg, A. P.

10.1101/2023.06.08.544045 — genomics — Posted on 2023-06-09

3110 A novel platform for metabolomics using barcoded structure-switching aptamers

Tan, J. H.; Mercado, M. P.; Fraser, A. G.

10.1101/2023.06.09.544402 — genomics — Posted on 2023-06-09

3111 Proactive Versus Reactive Control Strategies Differentially Mediate Alcohol Drinking in Wistar and P rats

Morningstar, M. D.; Timme, N.; Ma, B.; Cornwell, E.; Galbari, T.; Lapish, C.

10.1101/2023.06.08.544260 — neuroscience — Posted on 2023-06-09

3112 Expansion-assisted selective plane illumination microscopy for nanoscale imaging ofcentimeter-scale tissues

Glaser, A.; Chandrashekar, J.; Vasquez, J.; Arshadi, C.; Ouellette, N.; Jiang, X.; Kovacs, G.; Woodard, M.; Seshamani, S.; Cao, K.; Clack, N.; Recknagel, A.; Grim, A.; Balaram, P.; Turschak, E.; Liddell, A.; Rohde, J.; Baka, J.; Hellevik, A.; Takasaki, K.; Erion Barner, L.; Logsdon, M.; Chronopoulos, C.; de Vries, S.; Ting, J.; Perlmutter, S.; Kalmbach, B.; Dembrow, N.; Reid, R. C.; Feng, D.; Svoboda, K.

10.1101/2023.06.08.544277 — neuroscience — Posted on 2023-06-09

3113 Can higher aggressiveness effectively compensate for a virulence deficiency in plant pathogen? A case study of Puccinia triticina's fitness evolution in a diversified varietal landscape

Fontyn, C.; Meyer, K. J.; Boixel, A.-L.; Picard, C.; Destanque, A.; Marcel, T. C.; Suffert, F.; Goyeau, H.

10.1101/2023.06.09.544363 — plant biology — Posted on 2023-06-09

3114 Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind the same epitope

Spoendlin, F. C.; Abanades, B.; Raybould, M. I. J.; Wong, W. K.; Georges, G.; Deane, C. M.

10.1101/2023.06.09.543890 — bioinformatics — Posted on 2023-06-09

3115 emObject: domain specific data abstraction for spatial omics

Baker, E. A. G.; Huang, M.-Y.; Lam, A.; Rahim, M. K.; Bieniosek, M. F.; Wang, B.; Zhang, N. R.; Mayer, A. T.; Trevino, A. E.

10.1101/2023.06.07.543950 — bioinformatics — Posted on 2023-06-09

3116 Directing polymorph specific calcium carbonate formation with de novo protein templates

Davila Hernandez, F. A.; Jin, B.; Pyles, H.; Zhang, S.; Wang, Z.; Huddy, T. F.; Chen, C.-L.; De Yoreo, J. J.; Baker, D.

10.1101/2023.06.09.544362 — biochemistry — Posted on 2023-06-09

3117 Antibiotic that inhibits trans-translation blocks binding of EF-Tu to tmRNA but not to tRNA

Marathe, N.; Nguyen, H. A.; Alumasa, J. N.; Kuzmishin Nagy, A. B.; Vazquez, M. Y.; Dunham, C. M.; Keiler, K. C.

10.1101/2023.06.09.544387 — biochemistry — Posted on 2023-06-09

3118 Condition-dependent fitness effects of large synthetic chromosome amplifications

Keller, A.; Gao, L. L.; Witten, D.; Dunham, M. J.

10.1101/2023.06.08.544269 — genetics — Posted on 2023-06-09

3119 Frequent transitions in mating-type locus chromosomal organization in Malassezia and early steps in sexual reproduction

Coelho, M. A.; Ianiri, G.; David-Palma, M.; Theelen, B.; Goyal, R.; Narayanan, A.; Lorch, J. M.; Sanyal, K.; Boekhout, T.; Heitman, J.

10.1101/2023.03.25.534224 — genetics — Posted on 2023-06-09

3120 Biogeography and the evolution of acoustic communication in the polyploid North American gray treefrog complex

Booker, W. W.; Lemmon, E. M.; Lemmon, A. R.; Ptacek, M. B.; Hassinger, A. T.; Schul, J.; Gerhardt, H. C.

10.1101/2023.04.03.535469 — evolutionary biology — Posted on 2023-06-09

3121 Larval and adult traits coevolve in response to coastal oceanography to shape marine dispersal kernels

Peniston, J. H.; Burgess, S. C.

10.1101/2022.12.19.521131 — evolutionary biology — Posted on 2023-06-09

3122 Elevated Expression of srp RiPPs Across Bacterial Phyla in Marine Sponges

Waterworth, S. C.; Rees, E. R.; Clark, C.; Carlson, S.; Miller, I. J.; Puglisi, M.; Kwan, J. C.

10.1101/2023.06.09.544420 — ecology — Posted on 2023-06-09

3123 Distinctive Whole-brain Cell-Types Strongly Predict Tissue Damage Patterns in Eleven Neurodegenerative Disorders

Pak, V.; Adewale, Q.; Bzdok, D.; Dadar, M.; Zeighami, Y.; Iturria Medina, Y.

10.1101/2023.06.08.544227 — neuroscience — Posted on 2023-06-09

3124 Sex specific role of RNA-binding protein, AUF1, on prolonged hypersensitivity after repetitive ischemia with reperfusion injury

Quijas, M. M.; Queme, L. F.; Weyler, A. A.; Butterfiled, A.; Joshi, D. P.; Mitxelena-Balerdi, I.; Jankowski, M. P.

10.1101/2023.06.08.544080 — neuroscience — Posted on 2023-06-09

3125 Vision rivals audition in alerting humans for fast action

Dietze, N.; Poth, C. H. H.

10.1101/2023.06.02.543380 — neuroscience — Posted on 2023-06-09

3126 Ouvrai: Opening access to remote VR studies of human behavioral neuroscience

Cesanek, E.; Shivkumar, S.; Ingram, J. N.; Wolpert, D. M.

10.1101/2023.05.23.542017 — neuroscience — Posted on 2023-06-09

3127 Timbral effects on consonance illuminate psychoacoustics of music evolution

Marjieh, R.; Harrison, P. M. C.; Lee, H.; Deligiannaki, F.; Jacoby, N.

10.1101/2022.06.14.496070 — neuroscience — Posted on 2023-06-09

3128 Genetic circuits for feedback control of gamma-aminobutyric acid biosynthesis in probiotic Escherichia coli Nissle 1917

Lebovich, M.; Andrews, L. B.

10.1101/2023.06.09.544351 — synthetic biology — Posted on 2023-06-09

3129 The possible role of lipid bilayer properties in the evolutionary disappearance of betaine lipids in seed plants.

Bolik, S.; Schlaich, A.; Mukhina, T.; Amato, A.; Bastien, O.; Schneck, E.; Deme, B.; Jouhet, J.

10.1101/2023.01.24.525350 — plant biology — Posted on 2023-06-09

3130 A Deep Neural Network Two-part Model and Feature Importance Test for Semi-continuous Data

Zou, B.; Mi, X.; Xenakis, J.; Wu, D.; Hu, J.; Zou, F.

10.1101/2023.06.07.544106 — bioinformatics — Posted on 2023-06-09

3131 In silico discovery of the myxosortases that process MYXO-CTERM and three novel prokaryotic C-terminal protein-sorting signals that share invariant Cys residues

Haft, D. H.

10.1101/2023.06.07.544157 — bioinformatics — Posted on 2023-06-09

3132 Spatial Transcriptomic Cell-type Deconvolution Using Graph Neural Networks

Li, Y.; Luo, Y.

10.1101/2023.03.10.532112 — bioinformatics — Posted on 2023-06-09

3133 Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues

Rebollo, R.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.

10.1101/2023.05.27.542554 — bioinformatics — Posted on 2023-06-09

3134 Restoration of metabolic functional metrics from label-free, two-photon cervical tissue images using multiscale deep-learning-based denoising algorithms

Vora, N.; Polleys, C. M.; Sakellariou, F.; Georgalis, G.; Thieu, H.-T.; Genega, E. M.; Jahanseir, N.; Patra, A.; Miller, E.; Georgakoudi, I.

10.1101/2023.06.07.544033 — bioengineering — Posted on 2023-06-09

3135 Discovering the mechanics of artificial and real meat

St. Pierre, S. R.; Rajasekharan, D.; Darwin, E. C.; Linka, K.; Levenston, M. E.; Kuhl, E.

10.1101/2023.06.04.543638 — bioengineering — Posted on 2023-06-09

3136 Human TRMT2A methylates tRNA and contributes to translation fidelity

Witzenberger, M.; Burczyk, S.; Settele, D.; Mayer, W.; Welp, L. M.; Heiss, M.; Wagner, M.; Monecke, T.; Janowski, R.; Carell, T.; Urlaub, H.; Hauck, S. M.; Voigt, A.; Niessing, D.

10.1101/2022.12.28.522094 — biochemistry — Posted on 2023-06-09

3137 Blueprinting expandable nanomaterials with standardized protein building blocks

Huddy, T. F.; Hsia, Y.; Kibler, R. D.; Xu, J.; Bethel, N.; Nagarajan, D.; Redler, R.; Leung, P. J. Y.; Courbet, A.; Yang, E. C.; Bera, A. K.; Coudray, N.; Calise, S. J.; Davila-Hernandez, F. A.; Weidle, C.; Han, H. L.; Li, Z.; McHugh, R.; Reggiano, G.; Kang, A.; Sankaran, B.; Dickinson, M. S.; Coventry, B.; Brunette, T.; Liu, Y.; Dauparas, J.; Borst, A. J.; Ekiert, D.; Kollman, J. M.; Bhabha, G.; Baker, D.

10.1101/2023.06.09.544258 — biochemistry — Posted on 2023-06-09

3138 Travelling waves due to negative plant-soil feedbacks in a model including tree life-stages

Iuorio, A.; Baudena, M.; Eppinga, M. B.; Giannino, F.; Rietkerk, M.; Veerman, F.

10.1101/2023.06.09.544359 — ecology — Posted on 2023-06-09

3139 Intraspecific encounters can induce home-range shifts

Fagan, W. F.; Krishnan, A. G.; Liao, Q.; Fleming, C. H.; Liao, D. F.; Lamb, C.; Patterson, B.; Wheeldon, T.; Martinez-Garcia, R.; Menezes, J.; Noonan, M. J.; Gurarie, E.; Calabrese, J.

10.1101/2023.06.07.544097 — ecology — Posted on 2023-06-09

3140 Directed networks and resting-state effective brain connectivity with state-space reconstruction using reservoir computing causality

Falco-Roget, J.; Onicas, A. I.; Akwasi-Sarpong, F.; Crimi, A.

10.1101/2023.06.08.544175 — neuroscience — Posted on 2023-06-09

3141 Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain diseases

Karlsson, L.; Vogel, J.; Arvidsson, I.; Aström, K.; Janelidze, S.; Blennow, K.; Palmqvist, S.; Stomrud, E.; Mattsson-Carlgren, N.; Hansson, O.

10.1101/2023.06.08.544222 — neuroscience — Posted on 2023-06-09

3142 Exploring Correlation-Based Brain Networks with Adaptive Signed Random Walks

Sotero, R.; Bornot, J. M. S.

10.1101/2023.04.27.538574 — neuroscience — Posted on 2023-06-09

3143 Higher hyperpolarization activated current (Ih) in a subpopulation of hippocampal stratum oriens CA1 interneurons in Fragile X mice.

Hewitt, L. T.; Brager, D. H.

10.1101/2022.12.20.521268 — neuroscience — Posted on 2023-06-09

3144 Using predictive validity to compare associations between brain damage and behavior

Magnotti, J. F.; Patterson, J. S.; Schnur, T. T.

10.1101/2022.02.24.481802 — neuroscience — Posted on 2023-06-09

3145 Trait repetitive negative thinking in depression is associated with functional connectivity in negative thinking state rather than resting state

Misaki, M.; Tsuchiyagaito, A.; Guinjoan, S. M.; Rohan, M. L.; Paulus, M. P.

10.1101/2023.03.23.533932 — neuroscience — Posted on 2023-06-09

3146 Olfactory cortex output pathways exhibit robust differences in their ability to drive learned aversion

Vieira, I.; Bryzgalov, D.

10.1101/2023.06.04.541965 — neuroscience — Posted on 2023-06-09

3147 Heritable epigenetic changes are constrained by the dynamics of regulatory architectures

Jose, A. M.

10.1101/2023.06.07.544138 — systems biology — Posted on 2023-06-09

3148 Development of cell-free transcription-translation systems in three soil Pseudomonads

Meyerowitz, J. T.; Larsson, E. M.; Murray, R. M.

10.1101/2023.06.09.544292 — synthetic biology — Posted on 2023-06-09

3149 Exploring Ethylene-Related Genes in Cannabis sativa: Implications for Sexual Plasticity

Monthony, A. S.; de Ronne, M.; Torkamaneh, D.

10.1101/2023.04.28.538750 — plant biology — Posted on 2023-06-09

3150 Contrasting and conserved roles of NPR pathways in diverged land plant lineages

Jeon, H.-W.; Iwakawa, H.; Naramoto, S.; Herrfurth, C.; Gutsche, N.; Schlueter, T.; Kyozuka, J.; Miyauchi, S.; Feussner, I.; Zachgo, S.; Nakagami, H.

10.1101/2022.07.19.500630 — plant biology — Posted on 2023-06-09

3151 Protein-Protein Interaction Prediction is Achievable with Large Language Models

Hallee, L.; Gleghorn, J. P.

10.1101/2023.06.07.544109 — bioinformatics — Posted on 2023-06-09

3152 RETROFIT: REFERENCE-FREE DECONVOLUTION OF CELL-TYPE MIXTURES IN SPATIAL TRANSCRIPTOMICS

Singh, R.; He, X.; Park, A. K.; Hardison, R. C.; Zhu, X.; Li, Q.

10.1101/2023.06.07.544126 — bioinformatics — Posted on 2023-06-09

3153 LegNet: a best-in-class deep learning model for short DNA regulatory regions

Penzar, D.; Nogina, D.; Noskova, E.; Zinkevich, A.; Meshcheryakov, G.; Lando, A.; Rafi, A. M.; de Boer, C.; Kulakovskiy, I. V.

10.1101/2022.12.22.521582 — bioinformatics — Posted on 2023-06-09

3154 Identification of dialects and individuals of globally threatened Yellow Cardinals using neural networks

Bocaccio, H.; Dominguez, M.; Mahler, B.; Reboreda, J. C.; Mindlin, G. B.

10.1101/2023.06.07.544140 — ecology — Posted on 2023-06-09

3155 A novel sorting signal for RNA packaging into small extracellular vesicles

Oka, Y.; Tanaka, K.; Kawasaki, Y.

10.1101/2023.06.08.544286 — cell biology — Posted on 2023-06-09

3156 Unifying sparse coding, predictive coding, and divisive normalization

Lian, Y.; Burkitt, A. N.

10.1101/2023.06.08.544285 — neuroscience — Posted on 2023-06-09

3157 Metric information in cognitive maps: Euclidean embedding of non-Euclidean environments

Baumann, T.; Mallot, H. A.

10.1101/2023.06.09.544331 — neuroscience — Posted on 2023-06-09

3158 Daily Activity Profiles over the Lifespan of Female Medflies as Biomarkers of Aging and Longevity

Chen, H.; Müller, H.-G.; Rodovitis, V. G.; Papadopoulos, N. T.; Carey, J. R.

10.1101/2023.06.07.543948 — bioinformatics — Posted on 2023-06-09

3159 Associating Transcription Factors to Single-Cell Trajectories with DREAMIT

Maulding, N. D.; Seninge, L.; Stuart, J.

10.1101/2023.06.08.544214 — bioinformatics — Posted on 2023-06-09

3160 Successful placentation in human pregnancy is regulated by reciprocal interactions between maternal uterine NK cells and fetal placental trophoblast

Li, Q.; Sharkey, A.; Sheridan, M.; Magistrati, E.; Arutyunyan, A.; Huhn, O.; Sancho-Serra, C.; Anderson, H.; McGovern, N.; Esposito, L.; Fernando, R.; Gardner, L.; Vento-Tormo, R.; Turco, M. Y.; Moffett, A.

10.1101/2023.06.07.544122 — developmental biology — Posted on 2023-06-09

3161 Tapered Drug delivery, Optical stimulation, and Electrophysiology (T-DOpE) probes reveal the importance of cannabinoid signaling in hippocampal CA1 oscillations in behaving mice

Kim, J.; Huang, H.; Gilbert, E.; Arndt, K.; English, D. F.; Jia, X.

10.1101/2023.06.08.544251 — neuroscience — Posted on 2023-06-09

3162 Proteomic insights into mental health status: plasma markers in young adults

Afonin, A.; Piironen, A.-K.; Maciel, I. d. S.; Ivanova, M.; Alatalo, A.; Whipp, A. M.; Pulkkinen, L.; Rose, R. J.; van Kamp, I.; Kaprio, J.; Kanninen, K. M.

10.1101/2023.06.07.544039 — neuroscience — Posted on 2023-06-09

3163 METABOLIC MODELLING AS A POWERFUL TOOL TO IDENTIFY CRITICAL COMPONENTS OF THE PNEUMOCYSTIS GROWTH MEDIUM

Nev, O. A.; Zamaraeva, E.; De Oliveira, R.; Abou-Jaoude, W.; Ouattara, D. A.; Hoving, J. C.; Gudelj, I.; Brown, A. J. P.

10.1101/2023.06.07.544035 — systems biology — Posted on 2023-06-09

3164 BrainRBPedia: a resource for RNA-binding proteins relevant to neurodevelopmental disorders

Han, K.; Wainberg, M.; Calarco, J. A.; Smibert, C. A.; Lipshitz, H. D.; Lee, H. O.; Tripathy, S. J.

10.1101/2023.06.07.542483 — bioinformatics — Posted on 2023-06-09

3165 Modelling protein complexes with crosslinking mass spectrometry and deep learning

Stahl, K.; Brock, O.; Rappsilber, J.

10.1101/2023.06.07.544059 — bioinformatics — Posted on 2023-06-09

3166 A 3D in vitro cortical tissue model based on dense collagen to study the effects of gamma radiation on neuronal function

Lojek, N. M.; Williams, V. A.; Rogers, A. M.; Sajo, E.; Black, B. J.; Ghezzi, C. E.

10.1101/2023.06.07.544083 — bioengineering — Posted on 2023-06-09

3167 Restoration of metabolic functional metrics from label-free, two-photon cervical tissue images using multiscale deep-learning-based denoising algorithms

Vora, N.; Polleys, C. M.; Sakellariou, F.; Georgalis, G.; Thieu, H.-T.; Genega, E. M.; Jahanseir, N.; Patra, A.; Miller, E.; Georgakoudi, I.

10.1101/2023.06.07.544033 — bioengineering — Posted on 2023-06-09

3168 Alarm barks of male vervet monkeys as displays of male quality

Schad, L.; Dongre, P.; van de Waal, E.; Fischer, J.

10.1101/2023.06.08.544199 — animal behavior and cognition — Posted on 2023-06-09

3169 Aberrant landscapes of maternal meiotic crossoverscontribute to aneuploidies in human embryos

Ariad, D.; Madjunkova, S.; Madjunkov, M.; Chen, S.; Abramov, R.; Librach, C.; McCoy, R. C.

10.1101/2023.06.07.543910 — genomics — Posted on 2023-06-09

3170 Low genetic differentiation across an entire continent: the Scots pine paradox

Bruxaux, J.; Zhao, W.; Hall, D.; Curtu, A. L.; Androsiuk, P.; Drouzas, A. D.; Gailing, O.; Konrad, H.; Sullivan, A. R.; Semerikov, V.; Wang, X.-R.

10.1101/2023.06.09.543371 — evolutionary biology — Posted on 2023-06-09

3171 Overburdened Ferroptotic Stress Impairs Tooth Morphogenesis

Wang, H.; Wang, X.; Wang, C.; Yu, F.; Ye, L.

10.1101/2023.06.08.544273 — developmental biology — Posted on 2023-06-09

3172 Sleep disruption precedes forebrain synaptic Tau burden and contributes to cognitive decline in a sex-dependent manner in the P301S Tau transgenic mouse model

Martin, S. C.; Joyce, K. K.; Harper, K. M.; Nikolova, V. D.; Cohen, T. J.; Moy, S. S.; Diering, G. H.

10.1101/2023.06.07.544101 — neuroscience — Posted on 2023-06-09

3173 Astrocyte store-operated calcium entry is required for centrally mediated neuropathic pain

Prokhorenko, M. A.; Smyth, J. T.

10.1101/2023.06.08.544231 — neuroscience — Posted on 2023-06-09

3174 A Multi-omics Data Analysis Workflow Packaged as a FAIR Digital Object

Niehues, A.; de Visser, C.; Hagenbeek, F. A.; Kulkarni, P.; Pool, R.; Karu, N.; Kindt, A. S. D.; Singh, G.; Vermeiren, R. R. J. M.; Boomsma, D. I.; van Dongen, J.; 't Hoen, P. A. C.; van Gool, A. J.

10.1101/2023.06.07.543986 — bioinformatics — Posted on 2023-06-09

3175 Transcription dosage compensation does not occur in Down syndrome

Hunter, S.; Dowell, R. D.; Hendrix, J.; Freeman, J.; Allen, M. A.

10.1101/2023.06.07.543933 — bioinformatics — Posted on 2023-06-09

3176 An exploratory study of behavioral traits and the establishment of social relationships in female laboratory rats

Hakataya, S.; Katsu, N.; Okanoya, K.; Toya, G.

10.1101/2023.06.09.543342 — animal behavior and cognition — Posted on 2023-06-09

3177 A CD24+CD271+ melanoma cancer stem cell generates a diffuse hierarchy of attributes that promote metastasis and therapeutic resistance

Knowles, O.; Doldan, P.; Hillier-Richardson, I.; Lunt, S.; Youssef, G.; Gammon, L.; Mackenzie, I. C.; Philpott, M. P.; Rizvi, H.; Bergamaschi, D.; Harwood, C. A.; Biddle, A.

10.1101/2023.06.07.544036 — cancer biology — Posted on 2023-06-09

3178 Internalized beta2-Adrenergic Receptors Inhibit Subcellular Phospholipase C-Dependent Cardiac Hypertrophic Signaling

Wei, W.; Smrcka, A. V.

10.1101/2023.06.07.544153 — pharmacology and toxicology — Posted on 2023-06-09

3179 CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma

Cho, M. M.; Song, L.; Quamine, A. E.; Szewc, F.; Shi, L.; Erbe, A. K.; Ebben, J. D.; Turicek, D. P.; Kline, J. M.; Lafeber, E. O.; Phillips, M. F.; Ceas, A. S.; Sondel, P. M.; Capitini, C. M.

10.1101/2023.06.07.544144 — cancer biology — Posted on 2023-06-09

3180 otpb functions in a Lef1-dependent transcriptional network required for expression of the stress response inhibitor crhbp in the zebrafish hypothalamus

Figueroa, P.; Cheng, J.; Wang, G.; Kartchner, C.; Brito de Andrade, D.; Watters, H.; Crispell, E.; Dorsky, R.

10.1101/2023.06.07.544119 — neuroscience — Posted on 2023-06-09

3181 A Citrullus genus super-pangenome reveals extensive variations in wild and cultivated watermelons and sheds light on watermelon evolution and domestication

Wu, S.; Sun, H.; Gao, L.; Branham, S.; McGregor, C.; Xu, Y.; Kousik, C.; Wechter, P.; Levi, A.; Fei, Z.

10.1101/2023.06.08.544282 — plant biology — Posted on 2023-06-09

3182 Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH

Wang, H.; Barrow, F.; Fredrickson, G.; Florczak, K.; Ikramuddin, S.; Ruan, H.-B.; Jameson, S. C.; Revelo, X.

10.1101/2023.06.07.544061 — immunology — Posted on 2023-06-09

3183 Twilight length alters growth, flowering time, and clock function in Arabidopsis via LHY/CCA1

Mehta, D.; Scandola, S.; Tan, M.; Kennedy, C.; Uhrig, R. G.

10.1101/2023.06.09.544111 — plant biology — Posted on 2023-06-09

3184 Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's

Brimblecombe, K. R.; Conor-Robson, N.; Bataille, C. J. R.; Roberts, B. M.; Gracie, C.; te Water Naude, R.; Karthik, G.; Russell, A. J.; Wade-Martins, R.; Cragg, S. J.

10.1101/2020.07.03.186411 — neuroscience — Posted on 2023-06-09

3185 Senescence in yeast is associated with chromosome XII fragments rather than ribosomal DNA circle accumulation

Zylstra, A.; Hadj-Moussa, H.; Horkai, D.; Whale, A. J.; Piguet, B.; Houseley, J.

10.1101/2022.07.14.500009 — molecular biology — Posted on 2023-06-07

3186 Nanopore long-reads reveal fine structure of prokaryotic communities in mangrove sediments, like Illumina short-reads but with twice more taxa

Lemoinne, A.; Dirberg, G.; Georges, M.; Robinet, T.

10.1101/2023.06.06.541006 — molecular biology — Posted on 2023-06-07

3187 Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments

Musawi, S.; Donnio, L.-M.; Zhao, Z.; Magnani, C.; Binda, O.; Juang, J.; RASSINOUX, P.; Jacquier, A.; COUDERT, L.; Lomonte, P.; MARTINAT, c.; Schaeffer, L.; Cote, J.; Mari, P.-O.; Giglia-Mari, G.

10.1101/2022.11.04.515196 — molecular biology — Posted on 2023-06-07

3188 Oriented Display of Cello-Oligosaccharides for Pull-down Binding Assays to Distinguish Binding Preferences of Glycan Binding Proteins

Hackl, M.; Power, Z.; Chundawat, S. P. S.

10.1101/2023.01.26.525732 — molecular biology — Posted on 2023-06-07

3189 High-precision mapping of nuclear pore-chromatin interactions reveals new principles of genome organization at the nuclear envelope

Tyagi, S.; Capitanio, J. S.; Xu, J.; Chen, F.; Huang, J.; Sharma, R.; Hetzer, M. W.

10.1101/2021.05.10.443506 — molecular biology — Posted on 2023-06-07

3190 A CRISPR-based genome-wide screen for adipogenesis reveals new insights into mitotic expansion and lipogenesis.

Turn, R. E.; Hilgendorf, K. I.; Johnson, C. T.; Han, K.; Rabiee, A.; Demeter, J.; Ovais Aziz-Zanjani, M.; Domizi, P.; Cheng, R.; Zhu, Y.; Jiang, Z.; Svensson, K. J.; Bassik, M. C.; Jackson, P. K.

10.1101/2020.07.13.201038 — molecular biology — Posted on 2023-06-07

3191 Extracellular cysteine disulfide bond break at Cys122 disrupts PIP2-dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil Syndrome

Cruz, F. M.; Macias, A.; Moreno-Manuel, A. I. I.; Gutierrez, L. K.; Vera-Pedrosa, M. L.; Martinez-Carrascoso, I.; Sanchez-Perez, P.; Ruiz, J. M.; Bermudez-Jimenez, F. J. J.; Diaz Agustin, A.; Martinez, F.; Arias Santiago, S.; Braza-Boïls, A.; Martin Martinez, M.; Gutierrez Rodriguez, M.; Bernal, J. A.; Zorio, E.; Jimenez-Jaimez, J.; Jalife, J.

10.1101/2023.06.07.544151 — molecular biology — Posted on 2023-06-09

3192 Night-time neuronal activation of Cluster N in a North American songbird

Rudolf, J.; Philipello, N.; Fleihan, T.; Dickman, J. D.; Delmore, K. E.

10.1101/2023.06.07.544090 — neuroscience — Posted on 2023-06-09

3193 Identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes, supported by short- and long-read transcriptome data

10.1101/2023.06.09.544309 — biochemistry — Posted on 2023-06-09

3194 Evaluation of population structure inferred by principal component analysis or the admixture model

Wiuf, C.; Albrechtsen, A.; Garcia-Erill, G.; Li, S.; van Waaij, J.

10.1101/2023.06.06.543934 — genetics — Posted on 2023-06-09

3195 ERAP1 Shows Distinct Regulatory Mechanisms on Blood Pressure Modulation Between Males and Females

Ding, M.; Heydarpour, M.; Gomez, D. H.; Aljaibeji, H.; Parksook, W. W.; Peng, L.; Pojoga, L. H.; Romero, J. R.; Williams, G. H.

10.1101/2023.06.07.544152 — molecular biology — Posted on 2023-06-09

3196 Exposure to false cardiac feedback alters pain perception and anticipatory cardiac frequency.

Parrotta, E.; Bach, P.; Pezzulo, G.; Perrucci, M. G.; Costantini, M.; Ferri, F.

10.1101/2023.06.07.544025 — neuroscience — Posted on 2023-06-09

3197 Metabolic crosstalk between hydroxylated monoterpenes and salicylic acid in tomato defence response against Pseudomonas syringae pv tomato

Perez-Perez, J.; Minguillon, S.; Kabbas-Pinango, E.; Paya, C.; Campos, L.; Rodriguez-Concepcion, M.; Rodrigo, I.; Belles, J. M.; Lopez-Gresa, M. P.; Lison, P.

10.1101/2023.05.05.539605 — plant biology — Posted on 2023-06-09

3198 A prognostic matrix code defines functional glioblastoma phenotypes and niches.

Vishnoi, M.; Dereli, Z.; Yin, Z.; Kong, E. K.; Kinali, M.; Thapa, K.; Babur, O.; Yun, K.; Abdelfattah, N. H.; Li, X.; Bozorgui, B.; Rostomily, R. C.; Korkut, A.

10.1101/2023.06.06.543903 — cancer biology — Posted on 2023-06-09

3199 Location and concentration of aromatic-rich segments dictates the percolating inter-molecular network and viscoelastic properties of ageing condensates

Blazquez, S.; Sanchez-Burgos, I.; Ramirez, J.; Higginbotham, T.; Conde, M. M.; Collepardo-Guevara, R.; Tejedor, A. R.; Espinosa, J. R.

10.1101/2022.12.14.520383 — biophysics — Posted on 2023-06-09

3200 Computational workflow for predicting transcriptional modulation to achieve therapeutically desired cellular conversion for regenerative medicine

Mahadik, A.; Singh, V.

10.1101/2023.05.12.540496 — bioinformatics — Posted on 2023-06-09

3201 Inhibition of the glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess

Schiffer, L.; Oestlund, I.; Snoep, J.; Gilligan, L. C.; Taylor, A. E.; Sinclair, A. J.; Singhal, R.; Freeman, A.; Ajjan, R.; Tiganescu, A.; Arlt, W.; Storbeck, K.-H.

10.1101/2023.06.05.543687 — biochemistry — Posted on 2023-06-09

3202 Protein phosphatase 4 is required for Centrobin function in DNA damage repair

Rethi-Nagy, Z.; Abraham, E.; Sinka, R.; Juhasz, S.; Lipinszki, Z.

10.1101/2023.05.31.542826 — cell biology — Posted on 2023-06-09

3203 Analysis of RNA Exosome Subunit Transcript Abundance Across Tissues Implications for Neurological Disease Pathogenesis

de Amorim, J. L.; Asafu-Adjaye, D. G.; Corbett, A. H.

10.1101/2023.06.07.544082 — molecular biology — Posted on 2023-06-07

3204 Disruption of Prostaglandin F2α Receptor Signaling Attenuates Fibrotic Remodeling and Alters Fibroblast Population Dynamics in A Preclinical Murine Model of Idiopathic Pulmonary Fibrosis

Rodriguez, L. R.; Tang, S. Y.; Roque Barboza, W.; Murthy, A.; Tomer, Y.; Cai, T.-Q.; Iyer, S.; Chavez, K.; Das, U. S.; Ghosh, S.; Dimopoulos, T.; Babu, A.; Connelly, C.; FitzGerald, G. A.; Beers, M. F.

10.1101/2023.06.07.543956 — molecular biology — Posted on 2023-06-07

3205 Natriuretic peptides increase cGMP around cardiomyocyte mitochondria and protect against apoptosis

Calamera, G.; Ndongson-Dongmo, B.; Arunthavarajah, D.; Ovesen, M.; Kim, C.; Levy, F. O.; Andressen, K. W.; Moltzau, L. R.

10.1101/2022.08.22.504735 — pharmacology and toxicology — Posted on 2023-06-09

3206 Patterns and predictors of human-sloth bear conflict in Nepal: Implications for coexistence in unprotected forest landscapes

Pokharel, M.; Aryal, C.; Adhikary, B.; Rai, J.

10.1101/2022.08.24.505134 — ecology — Posted on 2023-06-09

3207 Prokaryotic winged helix domains as dsDNA adenine methylation sensors

Helbrecht, I.; Heiter, D.; Yang, W.; Lutz, T.; Ettwiller, L.; Bochtler, M.; Xu, S.-y.

10.1101/2023.06.07.544091 — molecular biology — Posted on 2023-06-07

3208 Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats

Tseng, Y.-J.; MALIK, I.; Deng, X.; Krans, A.; Jansen-West, K.; Tank, E. M. H.; Gomez, N. B.; Sher, R.; Petrucelli, L.; Barmada, S. J.; Todd, P.

10.1101/2023.06.07.544135 — molecular biology — Posted on 2023-06-07

3209 Sympathetic innervation directs Ankyrin G, voltage-gated Nav and KCNQ1 channels to the neuro-cardiac junctions

Shcherbakova, O. G.

10.1101/852129 — neuroscience — Posted on 2023-06-09

3210 SMYD5 is a novel epigenetic gatekeeper of the mild hypothermia response

Rafnsdottir, S.; Jang, K.; Halldorsdottir, S. T.; Tomasdottir, A.; Vinod, M.; Moller, K.; Reynisdottir, T.; Atladottir, L. H.; Allison, K. E.; He, J.; Zhang, L.; Northington, F. J.; Chavez-Valdez, R.; Anderson, K. J.; Bjornsson, H.

10.1101/2023.05.11.540170 — genetics — Posted on 2023-06-09

3211 Challenges and advances in methods for measuring phenotypic convergence

Grossnickle, D. M.; Brightly, W. H.; Weaver, L. N.; Stanchak, K. E.; Roston, R. A.; Pevsner, S. K.; Stayton, C. T.; Polly, P. D.; Law, C. J.

10.1101/2022.10.18.512739 — evolutionary biology — Posted on 2023-06-09

3212 Catalpol inhibits HHcy-induced EndMT in endothelial cells by modulating ROS/NF-κB signaling

Wu, C.; Wang, L.; Wang, X.

10.1101/2023.06.05.543810 — molecular biology — Posted on 2023-06-08

3213 Molecular Detection and Parasite Load Determination of Leishmania donovani in Dogs at Humera and Sheraro, Western Tigray, Ethiopia

Tadesse, H. F.; Van der Auwera, G.; Abera, B. H.; Maes, I.; Weldu, K.

10.1101/2023.04.10.536327 — molecular biology — Posted on 2023-06-08

3214 Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan.

Wimer, L.; Kaneshiro, K. R.; Ramirez, J.; Bose, N.; Contreras, M. V.; Shanmugam, M.; Gaffney, D.; Singh, P.; Beck, J.; Sellegounder, D.; Enriquez Najera, L.; Ellerby, L.; Cho, S.-J.; Newman, J.; Galligan, J.; Koliwad, S.; Kapahi, P.

10.1101/2022.08.10.503411 — molecular biology — Posted on 2023-06-08

3215 OMA1 protease eliminates arrested protein import intermediates upon depolarization of the inner mitochondrial membrane.

Krakowczyk, M.; Lenkiewicz, A. M.; Sitarz, T.; Marins Mussulini, B. H.; Linke, V.; Malinska, D.; Szczepankiewicz, A.; Wydrych, A.; Nieznanska, H.; Serwa, R. A.; Chacinska, A.; Bragoszewski, P.

10.1101/2023.06.08.543713 — molecular biology — Posted on 2023-06-08

3216 Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in Drosophila

Hanson, M. A.; Grollmus, L.; Lemaitre, B.

10.1101/2022.12.23.521774 — immunology — Posted on 2023-06-09

3217 Sensitivity analysis-guided Bayesian Parameter Estimation for Neural Mass Models: Applications in Epilepsy

Puthanmadam Subramaniyam, N.; Hyttinen, J.

10.1101/2023.04.03.535345 — neuroscience — Posted on 2023-06-09

3218 From autopoiesis to self-optimization: Toward an enactive model of biological regulation

Froese, T.; Weber, N.; Shpurov, I.; Ikegami, T.

10.1101/2023.02.05.527213 — systems biology — Posted on 2023-06-09

3219 Structural insight into CD93 recognition by IGFBP7

Xu, Y.; Sun, Y.; Zhu, Y.; Song, G.

10.1101/2023.06.07.543655 — cancer biology — Posted on 2023-06-08

3220 scMuffin: an R package for disentangling solid tumor heterogeneity from single-cell expression data

Nale, V.; Chiodi, A.; Di Nanni, N.; Cifola, I.; Moscatelli, M.; Cocola, C.; Gnocchi, M.; Piscitelli, E.; Sula, A.; Zucchi, I.; Reinbold, R.; Milanesi, L.; Mezzelani, A.; Pelucchi, P.; Mosca, E.

10.1101/2022.06.01.494129 — bioinformatics — Posted on 2023-06-09

3221 Computational workflow for predicting transcriptional modulation to achieve therapeutically desired cellular conversion for regenerative medicine

Mahadik, A.; Singh, V.

10.1101/2023.05.12.540496 — bioinformatics — Posted on 2023-06-09

3222 Cell-free chromatin particles released from dying cells inflict mitochondrial damage and ROS production in living cells

Raghuram, G. V.; Tripathy, B. K.; Avadhani, K.; Shabrish, S.; Khare, N. K.; Lopes, R.; Pal, K.; Mittra, I.

10.1101/2021.12.30.474529 — biochemistry — Posted on 2023-06-09

3223 The phosphoinositide signature guides the final step of plant cytokinesis

Lebecq, A.; Fangain, A.; Gascon, E.; Golgy, C.; Belcram, K.; Pastuglia, M.; Bouchez, D.; Caillaud, M.-C.

10.1101/2022.12.18.520917 — cell biology — Posted on 2023-06-09

3224 DNA-targeting short Argonaute triggers effector nuclease to protect bacteria from invaders

Prostova, M.; Kanevskaya, A.; Panteleev, V.; Lisitskaya, L.; Tugaeva, K. V.; Sluchanko, N. N.; Esyunina, D.; Kulbachiskiy, A.

10.1101/2023.06.08.544223 — molecular biology — Posted on 2023-06-08

3225 The Insertion Sequence Excision Enhancer (IEE): a PrimPol-based system for Immobilizing Transposon-Transmitted Antibiotic Resistance Genes?

Chandler, M. G.; Ross, K.; Varani, A. M.

10.1101/2023.06.07.543989 — microbiology — Posted on 2023-06-07

3226 Alterations in type 2 dopamine receptors across neuropsychiatric conditions: A large-scale PET cohort

Malen, T.; Santavirta, S.; De Maeyer, S.; Tuisku, J.; Kaasinen, V.; Kankare, T.; Isojärvi, J.; Rinne, J.; Hietala, J.; Nuutila, P.; Nummenmaa, L.

10.1101/2023.06.05.543660 — neuroscience — Posted on 2023-06-09

3227 Mutational hotspots lead to robust but suboptimal adaptive outcomes in certain environments

Flanagan, L. M.; Horton, J. S.; Taylor, T. B.

10.1101/2023.06.07.543998 — evolutionary biology — Posted on 2023-06-08

3228 Interdependence of a microtubule polymerase and a motor protein in establishment of kinetochore end-on attachments

Torvi, J. R.; Wong, J.; Drubin, D. G.; Barnes, G.

10.1101/2023.06.08.544255 — cell biology — Posted on 2023-06-08

3229 New viruses of Cladosporium sp. expand considerably the taxonomic structure of Gammapartitivirus genus

Jaccard, A.; Dubuis, N.; Kellenberger, I.; Brodard, J.; Schnee, S.; Gindro, K.; Schumpp, O.

10.1101/2023.06.06.543874 — microbiology — Posted on 2023-06-07

3230 Evaluating the ileal and cecal microbiota composition of a 1940 heritage genetic line and a 2016 commercial line of white leghorns fed representative diets from 1940 and 2016

Wall, D. C.; Dittoe, D.; Mahlerios, R. D.; Anderson, K. E.; Anthony, N. B.

10.1101/2023.06.08.544207 — microbiology — Posted on 2023-06-08

3231 Cholangiocytic differentiation drives cell proliferation in hepatoblastoma through Wnt-dependent FGF19 signaling

Wu, P. V.; Fish, M.; Hazard, F. K.; Zhu, C.; Vennam, S.; Walton, H. E.; Morri, M.; Neff, N.; West, R. B.; Nusse, R.

10.1101/2023.06.08.544267 — cancer biology — Posted on 2023-06-08

3232 IL-22 promotes acute kidney injury through activation of the DNA damage response and cell death in proximal tubule cells

Taguchi, K.; Sugahara, S.; Elias, B. C.; Pabla, N. S.; Canaud, G.; Brooks, C. R.

10.1101/2023.06.08.544134 — cell biology — Posted on 2023-06-08

3233 Soluble LIGHT (TNFSF14) activates endothelial cells, thereby priming the first vessel-occlusive events in acute sickle cell disease

Chadebech, P.; Nguyen-Peyre, K.-A.; Di Liberto, G.; Bodivit, G.; Pirenne, F.; Bartolucci, P.

10.1101/2023.06.08.541088 — cell biology — Posted on 2023-06-08

3234 Warming and altered precipitation independently and interactively suppress alpine soil microbial growth in a decadal-long experiment

Ruan, Y.; Ling, N.; Jiang, S.; Jing, X.; He, J.-S.; Shen, Q.; Nan, Z.

10.1101/2023.06.08.544195 — microbiology — Posted on 2023-06-08

3235 Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production

Nobe, M.; Maruzuru, Y.; Takeshima, K.; Maeda, F.; Kusano, H.; Yoshimura, R.; Nishiyama, T.; Park, H.; Kozaki, Y.; Iwami, S.; Koyanagi, N.; Kato, A.; Natsume, T.; Adachi, S.; Kawaguchi, Y.

10.1101/2023.06.07.544155 — microbiology — Posted on 2023-06-08

3236 Locus specific human endogenous retroviruses reveal new lymphoma subtypes

Singh, B.; Dopkins, N.; Fei, T.; Marston, J. L.; Michael, S.; Reyes-Gopar, H.; Curty, G.; Heymann, J. J.; Chadburn, A.; Martin, P.; Leal, F. E.; Cesarman, E.; Nixon, D. F.; Bendall, M. L.

10.1101/2023.06.08.544208 — cancer biology — Posted on 2023-06-08

3237 Neighbor cells restrain furrowing during epithelial cytokinesis

Landino, J.; Misterovich, E.; Chumki, S.; Miller, A. L.

10.1101/2023.06.08.544077 — cell biology — Posted on 2023-06-08

3238 The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A

Smits, J. P. H.; Qu, J.; Pardow, F.; van den Brink, N.; Rodijk-Olthuis, D.; Vlijmen, I.; van Heeringen, S. J.; Zeeuwen, P.; Schalkwijk, J.; Zhou, H.; van den Bogaard, E.

10.1101/2023.06.07.544032 — cell biology — Posted on 2023-06-08

3239 Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

Shopsin, B.; Podkowik, M.; Perault, A. I.; Putzel, G.; Pountain, A.; Kim, J.; DuMont, A.; Zwack, E.; Ulrich, R. J.; Karagounis, T. K.; Zhou, C.; Haag, A. F.; Shenderovich, J.; Wasserman, G. A.; Kwon, J.; Chen, J.; Richardson, A. R.; Weiser, J. N.; Nowosad, C. R.; Lun, D. S.; Zhao, X.; Parker, D.; Pironti, A.; Drlica, K. N.; Yanai, I.; Torres, V. J.

10.1101/2023.06.08.544038 — microbiology — Posted on 2023-06-08

3240 Isolation of a putative sulfur comproportionating microorganism

Aronson, H. S.; LaRowe, D. E.; Macalady, J. L.; Amend, J. P.

10.1101/2023.06.08.544259 — microbiology — Posted on 2023-06-08

3241 Acvr1b loss promotes formation of precancerous lesions from acinar and ductal cells of origin

Saeki, K.; Patil, S.; Sun, Y.; Su, G. H.; Kopp, J. L.

10.1101/2023.06.08.544226 — cancer biology — Posted on 2023-06-08

3242 Swimming ability and flagellar motility of sperm packets of the volvocine green alga Pleodorina starrii

Kage, A.; Takahashi, K.; Nozaki, H.; Higashiyama, T.; Baba, S. A.; Nishizaka, T.

10.1101/2023.06.08.544266 — biophysics — Posted on 2023-06-08

3243 Towards Pandemic-Scale Ancestral Recombination Graphs of SARS-CoV-2

Zhan, S. H.; Ignatieva, A.; Wong, Y.; Eaton, K.; Jeffery, B.; Palmer, D. S.; Murall, C. L.; Otto, S.; Kelleher, J.

10.1101/2023.06.08.544212 — evolutionary biology — Posted on 2023-06-08

3244 Genetic diversity, recombination and cross-species transmission of a waterbird gammacoronavirus in the wild

Francois, S.; Nazki, S.; Vickers, S. H.; Fournie, G.; Perrins, C. M.; Broadbent, A. J.; Pybus, O. G.; Hill, S. C.

10.1101/2023.06.08.544213 — ecology — Posted on 2023-06-08

3245 Whole body cell map tracks tissue-specific immune cell accumulation and plasticity loss through ageing

Mangiola, S.; Milton, M.; Ranathunga, N.; LiWaiSuen, C.; Yang, E.; Hutchison, W.; Garnham, A.; Iskander, J.; Pal, B.; Yadav, V. J.; Carey, V.; Kallies, A.; Bedoui, S.; Morgan, M.; Papenfuss, A. T.

10.1101/2023.06.08.542671 — immunology — Posted on 2023-06-08

3246 Heterogeneity of foam cell biogenesis across diseases

Guerrini, V.; Prideaux, B.; Khan, R.; Subbian, S.; Wang, Y.; Sadimin, E.; Pawar, S.; Ukey, R.; Singer, E. A.; Xue, C.; Gennaro, M. L.

10.1101/2023.06.08.542766 — immunology — Posted on 2023-06-08

3247 Trophic niche differentiation in the African elephant fish community (Mormyridae) from the Sanaga River in Cameroon

Sommer, G. M.; Njom, S. D.; Indermaur, A.; Bitja Nyom, A. R.; Horka, P.; Kukla, J.; Musilova, Z.

10.1101/2023.06.07.543841 — zoology — Posted on 2023-06-08

3248 In vivo intra-uterine delivery of TAT-fused Cre recombinase and CRISPR/Cas9 editing unveil histopathology of Pten/p53-deficient endometrial cancers.

Navaridas, R.; Vidal-Sabanes, M.; Ruiz-Mitjana, A.; Altes, G.; Perramon-Guell, A.; Yeramian, A.; Egea, J.; Encinas, M.; Gatius, S.; Matias-Guiu, X.; Dolcet, X.

10.1101/2023.06.08.544224 — pathology — Posted on 2023-06-08

3249 Spontaneous transfer of small peripheral peptides between supported lipid bilayer and giant unilamellar vesicles

Efodili, E.; Knight, A.; Mirza, M.; Briones, C.; Lee, I.-H.

10.1101/2023.06.08.544237 — biophysics — Posted on 2023-06-08

3250 Brewing COFFEE: a sequence-specific coarse-grained energy function for simulations of DNA-protein complexes

Chakraborty, D.; Mondal, B.; Thirumalai, D.

10.1101/2023.06.07.544064 — biophysics — Posted on 2023-06-08

3251 Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis

Colazo, J. M.; Hoogenboezem, E. N.; Shah, V.; Yu, F.; Lo, J. H.; Sorets, A. G.; Francini, N.; Cho, H.; Michell, D. L.; Vickers, K. C.; Gibson-Corley, K. N.; Hasty, K. A.; Crofford, L.; Cook, R. S.; Duvall, C. L.

10.1101/2023.05.31.542971 — bioengineering — Posted on 2023-06-08

3252 A mutational atlas for Parkin proteostasis

Clausen, L.; Voutsinos, V.; Cagiada, M.; Johansson, K. E.; Gronbaek-Thygesen, M.; Nariya, S.; Powell, R. L.; Have, M. K.; Oestergaard, V. H.; Stein, A.; Fowler, D. M.; Lindorff-Larsen, K.; Hartmann-Petersen, R.

10.1101/2023.06.08.544160 — biochemistry — Posted on 2023-06-08

3253 Setdb1 safeguards genome integrity in muscle stem cells to allow for regenerative myogenesis and inflammation

Garcia, P.; Jarassier, W.; Brun, C.; Giordani, L.; Peccate, C.; Agostini, F.; Kung, W. H.; Cheung, T.; Le Grand, F.

10.1101/2023.06.08.544190 — cell biology — Posted on 2023-06-08

3254 Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis

Biton, T.; Scher, N.; Carmon, S.; Elbaz-Alon, Y.; Schejter, E. D.; Shilo, B.-Z.; Avinoam, O.

10.1101/2023.06.08.544180 — cell biology — Posted on 2023-06-08

3255 Nutrient enrichment alters gene expression in 'Ca.' Aquarickettsia rohweri, promoting parasite expansion and horizontal transmission

Speare, L.; Klinges, J. G.; Duke, W. C.; Muller, E. M.; Thurber, R. L. V.

10.1101/2023.06.08.544262 — microbiology — Posted on 2023-06-08

3256 Identification and functional characterization of the putative members of the CTDK-1 kinase complex as regulators of growth and development in the genus Aspergillus.

Agirrezabala, Z.; Guruceaga, X.; Martin-Vicente, A.; Otamendi, A.; Fagoaga, A.; Fortwendel, J. R.; Espeso, E. A.; Etxebeste, O.

10.1101/2023.06.08.544166 — microbiology — Posted on 2023-06-08

3257 Gender-based heterogeneity of FAHFAs in trained runners

Nelson, A. B.; Chow, L. S.; Dengel, D. R.; Pan, M.; Hughey, C. C.; Han, X.; Puchalska, P.; Crawford, P. A.

10.1101/2023.06.07.543941 — physiology — Posted on 2023-06-08

3258 Structural insights into context-dependent inhibitory mechanisms of chloramphenicol in cells

Xue, L.; Spahn, C. M. T.; Schacherl, M.; Mahamid, J.

10.1101/2023.06.07.544107 — biophysics — Posted on 2023-06-08

3259 Automated cell annotation in multi-cell images using an improved CRF_ID algorithm

Lee, H. J.; Liang, J.; Chaudhary, S.; Moon, S.; Yu, Z.; Wu, T.; Liu, H.; Choi, M.-K.; Zhang, Y.; Lu, H.

10.1101/2023.06.07.543949 — bioengineering — Posted on 2023-06-08

3260 Molecular basis of VEGFR1 autoinhibition at the plasma membrane

Chakraborty, M. P.; Das, D.; Mondal, P.; Kaul, P.; Bhattacharyya, S.; Das, P. K.; Das, R.

10.1101/2023.06.08.544162 — biochemistry — Posted on 2023-06-08

3261 An evolutionarily conserved strategy for ribosome binding and inhibition by β-coronavirus non-structural protein 1

Maurina, S. F.; O'Sullivan, J. P.; Sharma, G.; Pineda Rodriguez, D. C.; MacFadden, A.; Cendali, F.; Henen, M. A.; Kieft, J. S.; Glasgow, A.; Steckelberg, A.-L.

10.1101/2023.06.07.544141 — biochemistry — Posted on 2023-06-08

3262 A conserved and druggable pocket in class B G protein coupled receptors for orally active small molecule agonists

Xu, H. E.; Zhao, L.; He, Q.; Yuan, Q.; Gu, Y.; He, X.; Shan, H.; Li, J.; Wang, K.; Li, Y.; Hu, W.; Wu, K.; Shen, J.

10.1101/2023.06.08.544171 — biochemistry — Posted on 2023-06-08

3263 The mechanical force with the physiological movement works as a biological cue in tendon development during the postnatal phase in mice

Usami, Y.; Kokubun, T.

10.1101/2023.06.02.543346 — developmental biology — Posted on 2023-06-08

3264 Single-cell RNA sequencing reveals HIF1A as a severity-sensitive immunological scar in circulating monocytes of convalescent comorbidity-free COVID-19 patients

Zielinski, C.; May, L.; Chu, C.-F.

10.1101/2023.06.07.544062 — immunology — Posted on 2023-06-08

3265 Anti-Viral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein Against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden Hamster Models

Dhanushkodi, N.; Prakash, S.; Quadiri, A.; Zayou, L.; Srivastava, R.; Shaik, A. M.; Suzer, B.; Ibraim, I. C.; Landucci, G.; Tifrea, D. F.; Singer, M.; Jamal, L.; Edwards, R. A.; Vahed, H.; Brown, L.; BENMOHAMED, L.

10.1101/2023.06.07.544133 — immunology — Posted on 2023-06-08

3266 Mapping the computational similarity of individual neurons within large-scale ensemble recordings using the SIMNETS analysis framework

Hynes, J. B.; Brandman, D. M.; Zimmermann, J. B.; Donoghue, J. P.; Vargas-Irwin, C. E.

10.1101/463364 — neuroscience — Posted on 2023-06-08

3267 Loss of LRP1 from GABAergic neurons impairs memory function

Uner, A. A.; Hou, Z.-S.; Aydogan, A.; Rodrigues, K. C. d. C.; Young, J.; Choi, A.; Yang, W.-M.; Kim, W.; PREVOT, V.; Caldarone, B. J.; Lee, H.; Kim, Y.-B.

10.1101/2022.09.17.508390 — neuroscience — Posted on 2023-06-08

3268 Multiplexed volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex

Han, X.; Lu, X.; Li, P. H.; Wang, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Adhinarta, J.; Berger, D.; Wu, Y.; Fang, T.; Meral, E. S.; Asraf, S.; Ploegh, H.; Pfister, H.; Wei, D.; Jain, V.; Trimmer, J. S.; Lichtman, J. W.

10.1101/2023.05.20.540091 — neuroscience — Posted on 2023-06-08

3269 Large-scale map of RNA binding protein interactomes across the mRNA life-cycle

Street, L.; Rothamel, K.; Brannan, K.; Jin, W.; Bokor, B.; Dong, K.; Rhine, K.; Madrigel, A.; Al-Azzam, N.; Kim, J.; Ma, Y.; Abdou, A.; Wolin, E.; Doron-Mandel, E. W.; Ahdout, J.; Mujumba, M.; Jovanovic, M.; Yeo, G. W.

10.1101/2023.06.08.544225 — systems biology — Posted on 2023-06-08

3270 Bacterial lag phase shortening is triggered by methyl groups

Sperfeld, M.; Narvaez-Barragan, D. A.; Malitsky, S.; Frydman, V.; Yuda, L.; Rocha, J.; Segev, E.

10.1101/2023.06.06.543872 — microbiology — Posted on 2023-06-07

3271 Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and to colonize humanized mice

Hamblin, M.; Schade, R.; Narasimhan, R.; Monack, D. M.

10.1101/2023.06.06.543980 — microbiology — Posted on 2023-06-07

3272 TMELand: An end-to-end pipeline for quantification and visualization of Waddington's epigenetic landscape based on gene regulatory network

Zhu, L.; Kang, X.; Li, C.; Zheng, J.

10.1101/2023.06.07.543805 — systems biology — Posted on 2023-06-08

3273 Fluctuations in tissue growth portray homeostasis as a critical state and long-time non-Markovian cell proliferation as Markovian

Lavalle, N. G.; Chara, O.; Grigera, T. S.

10.1101/2023.06.07.544008 — biophysics — Posted on 2023-06-08

3274 ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes

Kostina, A.; Lewis-Israeli, Y.; Abdelhamid, M.; Gabalski, M.; Volmert, B.; Lankerd, H.; Huang, A.; Wasserman, A.; Lydic, T.; Chan, C.; Olomu, I.; Aguirre, A.

10.1101/2023.06.07.544081 — bioengineering — Posted on 2023-06-08

3275 Investigating the role of Mce proteins in Mycobacterium avium paratuberculosis infection

Blake, R.; Jensen, K.; Alfituri, O.; Mabbott, N. A.; Hope, J.; Stevens, J.

10.1101/2023.06.06.543821 — microbiology — Posted on 2023-06-07

3276 Functional characterization of helminth-associated Clostridiales reveals covariates of Treg differentiation

Sargsian, S.; Lejeune, A.; Ercelen, D.; Jin, W.-B.; Varghese, A.; Loke, P.; Lim, Y. A. L.; Guo, C.-J.; Cadwell, K.

10.1101/2023.06.05.543751 — microbiology — Posted on 2023-06-07

3277 CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells

Horvath, R.; Brumme, Z. L.; Sadowski, I.

10.1101/2023.06.07.544021 — microbiology — Posted on 2023-06-07

3278 Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington's Disease

Pressl, C.; Mätlik, K.; Kus, L.; Darnell, P.; Luo, J.-D.; Paul, M. R.; Weiss, A. R.; Liguore, W.; Carroll, T.; Davis, D. A.; McBride, J.; Heintz, N.

10.1101/2023.04.24.538096 — neuroscience — Posted on 2023-06-08

3279 Molecular architecture and conservation of an immature human endogenous retrovirus

Krebs, A.-S.; Liu, H.-F.; Zhou, Y.; Rey, J. S.; Levintov, L.; Shen, J.; Howe, A.; Perilla, J. R.; Bartesaghi, A.; Zhang, P.

10.1101/2023.06.07.544027 — microbiology — Posted on 2023-06-07

3280 Chitin degradation by Synechococcus WH7803

Capovilla, G.; Castro, K. G.; Collani, S.; Kearney, S. M.; Kehoe, D. M.; Chisholm, S. W.

10.1101/2023.06.07.544114 — microbiology — Posted on 2023-06-07

3281 Machine Learning Workflow for Single-Cell Antimicrobial Susceptibility Testing of Klebsiella pneumoniae to Meropenem in Sub-Doubling Time

Tjandra, K. C.; Ram-Mohan, N. C.; Roshardt, M.; Qu, Z.; Zudock, E. J.; Mach, K. E.; Erminaga, O.; Liao, J. C.; Yang, S.; Wong, P. K.

10.1101/2022.11.03.515093 — microbiology — Posted on 2023-06-07

3282 56Fe ion exposure increases the incidence of lung and brain tumors at a similar rate in male and female mice

Finkelstein, S. R.; Patel, R.; Deland, K.; Mercer, J.; Starr, B.; Zhu, D.; Min, H.; Reinsvold, M.; Campos, L. D. S.; Williams, N.; Luo, L.; Ma, Y.; Neff, J.; Hoenerhoff, M.; Moding, E. J.; Kirsch, D. G.

10.1101/2023.06.06.543754 — cancer biology — Posted on 2023-06-08

3283 Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to cytotoxicity of human lung cells

Scasny, A.; Alibayov, B.; Khan, F.; Rao, S.; Murin, L.; Vidal, A. G.; Smith, P.; Wei, L.; Edwards, K. S.; Warncke, K.; Vidal, J. E.

10.1101/2023.06.07.544089 — microbiology — Posted on 2023-06-07

3284 Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice

Thiriot, J. D.; Liang, Y.; Gonzales, C.; Sun, J.; Soong, L.

10.1101/2023.06.07.543994 — immunology — Posted on 2023-06-08

3285 Iron Oxide Nanoparticles Coated with Biodegradable Block-Copolymer PDMAEMA-b-PMPC and Functionalized with Aptamer for HER2 Breast Cancer Cell Identification

de Valega Negrao, C. v. Z.; Cerize, N. N. P.; Justo-Junior, A. d. S.; Liszbinski, R. B.; Meneguetti, G. P.; Araujo, L.; Rocco, S. A.; Goncalves, K. d. A.; Cornejo, D. R.; Leo, P.; Perecin, C.; Adamoski, D.; Dias, S. M. G.

10.1101/2023.06.06.543859 — cancer biology — Posted on 2023-06-08

3286 Identification of disulfidptosis-related-ferroptosis associated lncRNAs signature as a novel prognosis model for kidney renal clear cell carcinoma

Xu, Z.

10.1101/2023.06.06.543974 — cancer biology — Posted on 2023-06-08

3287 Diversity of function and higher-order structure within HWE sensor histidine kinases

Dikiy, I.; Swingle, D.; Toy, K.; Edupuganti, U. R.; Rivera-Cancel, G.; Gardner, K. H.

10.1101/2020.07.08.194225 — biochemistry — Posted on 2023-06-08

3288 Genetic architecture of individual meiotic crossover rate and distribution in a large Atlantic Salmon (Salmo salar) breeding population.

Brekke, C.; Johnston, S. E.; Knutsen, T. M.; Berg, P.

10.1101/2023.06.07.543993 — genetics — Posted on 2023-06-08

3289 Unpredictable soil conditions affect the prevalence of a microbial symbiosis

Scott, T. J.; Stephenson, C. J.; Rao, S.; Queller, D.; Strassmann, J. E.

10.1101/2023.06.07.543465 — evolutionary biology — Posted on 2023-06-08

3290 The AMPK-TORC1 signalling axis regulates caffeine-mediated DNA damage checkpoint override and cell cycle effects in fission yeast

Alao, J.-P.; Rallis, C.

10.1101/2022.11.08.515652 — cell biology — Posted on 2023-06-08

3291 METTL16 Controls Kaposi's Sarcoma-Associated Herpesvirus Replication by Regulating S-Adenosylmethionine Cycle

Zhang, X.; Meng, W.; Feng, J.; Gao, X.; Qin, C.; Feng, P.; Huang, Y.; Gao, S.-J.

10.1101/2023.06.07.544118 — microbiology — Posted on 2023-06-07

3292 Oxygen production via NO dismutation in different ammonia oxidizers.

Hernandez-Magana, E.; Canfield, D. E.; Kraft, B.

10.1101/2023.06.07.544047 — microbiology — Posted on 2023-06-07

3293 Evolution of a fruit fly antimicrobial peptide family to control microbiome bacteria present in the host ecology

Hanson, M. A.; Grollmus, L.; Lemaitre, B.

10.1101/2022.12.23.521774 — immunology — Posted on 2023-06-08

3294 Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

Dasgupta, A.; Reagor, C. C.; Paik, S. P.; Snow, L. M.; Jacobo, A.; Hudspeth, A.

10.1101/2022.11.17.516962 — neuroscience — Posted on 2023-06-08

3295 EZH2 inhibition promotes tumor immunogenicity in lung squamous cell carcinomas

DuCote, T. J.; Song, X.; Naughton, K.; Chen, F.; Plaugher, D. R.; Childress, A. R.; Edgin, A. R.; Qu, X.; Liu, J.; Liu, J.; Li, F.; Wong, K.-K.; Brainson, C. F.

10.1101/2023.06.06.543919 — cancer biology — Posted on 2023-06-08

3296 Grubraw, a chemogenetic generator of mitochondrial pyruvate, reveals new mechanisms of mitochondrial metabolic control that underlie the Warburg effect

Potekhina, E. S.; Bass, D. Y.; Ivanenko, A. V.; Moshchenko, A. A.; Korzhenevskiy, D. A.; Karnaeva, A. E.; Zakirova, N. F.; Ivanov, A. V.; Shimolina, L. E.; Shirmanova, M. V.; Lyang, O. V.; Patsap, O. I.; Bogeski, I.; Nesterenko, A. M.; Belousov, V.

10.1101/2023.04.18.537329 — cancer biology — Posted on 2023-06-08

3297 Identification of CD133+ Intercellsomes in Intercellular Communication to Offset Intracellular Signal Deficit

Kaneko, K.; Liang, Y.; Liu, Q.; Zhang, S.; Scheiter, A.; Song, D.; Feng, G.-S.

10.1101/2022.05.16.492226 — cancer biology — Posted on 2023-06-08

3298 Microbiome time series data reveal predictable patterns of change

Karwowska, Z.; Szczerbiak, P.; Kosciolek, T.

10.1101/2023.06.08.544023 — bioinformatics — Posted on 2023-06-08

3299 Engineering Yeast to Improve Heterologous Abscisic Acid Production

Otto, M.; Gossing, M.; David, F.; Siewers, V.

10.1101/2023.06.07.544016 — bioengineering — Posted on 2023-06-08

3300 The first complete genome of the extinct European wild ass (Equus hemionus hydruntinus)

Özkan, M.; Gürün, K.; Yüncü, E.; Vural, K. B.; Atag, G.; Akbaba, A.; Fidan, F. R.; Saglıcan, E.; Altınısık, N. E.; Koptekin, D.; Pawłowska, K.; Hodder, I.; Adcock, S. E.; Arbuckle, B. S.; Steadman, S. R.; McMahon, G.; Erdal, Y. S.; Bilgin, C. C.; Geigl, E.-M.; Götherström, A.; Grange, T.; Özer, F.; Somel, M.

10.1101/2023.06.05.543765 — genomics — Posted on 2023-06-07

3301 A dual-fluorescent recombinant for live observation of Herpes simplex-type 1 infection outcomes.

Domanico, L. F.; Dunn, G. P.; Kobiler, O.; Taylor, M. P.

10.1101/2023.06.07.544108 — microbiology — Posted on 2023-06-07

3302 Aspergillus fumigatus cytochrome c impacts conidial survival during sterilizing immunity

James, M. R.; Aufiero, M.; Vesely, E. M.; Dhingra, S.; Liu, K.-W.; Hohl, T. M.; Cramer, R. A.

10.1101/2023.06.07.544103 — microbiology — Posted on 2023-06-07

3303 Large-scale map of RNA binding protein interactomes across the mRNA life-cycle

Rothamel, K.; Street, L.; Brannan, K.; Jin, W.; Rhine, K.; Al-Azzam, N.; Wolin, E.; Bokor, B.; Abdou, A.; Doron-Mandel, E. W.; Kim, J.; Ma, Y.; Ahdout, J.; Dong, K.; Madrigel, A.; Mujumba, M.; Jovanovic, M.; Yeo, G. W.

10.1101/2023.06.08.544225 — systems biology — Posted on 2023-06-08

3304 Characterising genome composition and large structural variation in banana varietal groups

Higgins, J.; Osorio-Guarin, J. A.; Olave-Achuri, C.; Toloza-Moreno, D. L.; Enriquez, A.; Di Palma, F.; Yockteng, R.; De Vega, J. J.

10.1101/2023.06.08.544197 — plant biology — Posted on 2023-06-08

3305 Deterministic Early Endosomal Maturations Emerge From a Stochastic Trigger-and-Convert Mechanism

York, H. M.; Joshi, K.; Wright, C. S.; Kreplin, L. Z.; Rodgers, S.; Moorthi, U. K.; Gandhi, H.; Patil, A.; Mitchell, C.; Iyer-Biswas, S.; Arumugam, S.

10.1101/2022.04.15.488498 — biophysics — Posted on 2023-06-08

3306 escheR: Unified multi-dimensional visualizations with Gestalt principles

Guo, B.; Huuki-Myers, L. A.; Grant-Peters, M.; Collado-Torres, L.; Hicks, S. C.

10.1101/2023.03.18.533302 — bioinformatics — Posted on 2023-06-08

3307 High Coverage Highly Accurate Long-Read Sequencing of a Mouse Neuronal Cell Line Using the PacBio Revio Sequencer

Manuel, J. G.; Heins, H. B.; Crocker, S.; Neidich, J. A.; Sadzewicz, L.; Tallon, L.; Turner, T. N.

10.1101/2023.06.06.543940 — genomics — Posted on 2023-06-07

3308 Differential usage of DNA modifications in neurons, astrocytes, and microglia

Tooley, K. B.; Chucair-Elliott, A. J.; Ocanas, S. R.; Machalinski, A. H.; Pham, K. D.; Stanford, D. R.; Freeman, W. M.

10.1101/2023.06.05.543497 — genomics — Posted on 2023-06-07

3309 Multiple repeat regions within mouse DUX recruit chromatin regulators to facilitate an embryonic gene expression program

Smith, C. M.; Grow, E. J.; Shadle, S. C.; Cairns, B. R.

10.1101/2023.03.29.534786 — developmental biology — Posted on 2023-06-08

3310 A Spatiotemporal Compartmentalization of Glucose Metabolism Guides Mammalian Gastrulation Progression

Cao, D.; Zhong, L.; Hemalatha, A.; Bergmann, J.; Cox, A. L.; Greco, V.; Sozen, B.

10.1101/2023.06.06.543780 — developmental biology — Posted on 2023-06-08

3311 Circular viral copy DNA of Dengue virus (DENV-2) isolated from infected mosquito cell cultures

Kanthong, N.; Flegel, T. W.; Gangnonngiw, W.; Thongda, W.

10.1101/2023.06.07.544120 — microbiology — Posted on 2023-06-07

3312 Bringing up-to-date the toolkit for the catabolism of aromatic compounds in fungi: the unexpected 1,2,3,5-tetrahydroxybenzene central pathway

Martins, T. M.; Bento, A.; Martins, C.; Tome, A. S.; Moreira, C. J. S.; Silva Pereira, C.

10.1101/2023.06.06.543907 — microbiology — Posted on 2023-06-08

3313 Three small partner proteins facilitate the type VII-dependent secretion export of an antibacterial nuclease

Yang, Y.; Boardman, E.; Deme, J. C.; Alcock, F.; Lea, S. M.; Palmer, T.

10.1101/2023.04.01.535202 — microbiology — Posted on 2023-06-08

3314 The histone lysine demethylase KDM5C fine-tunes gene expression to regulate dendritic cell heterogeneity and function

Guak, H.; Weiland, M. J.; VanderArk, A. R.; Zhai, L.; Lau, K.; Mabvakure, B.; Corrado, M.; Davidson, P.; Compton, S.; DeCamp, L.; Scullion, C.; Jones, R. M.; Nowinski, S.; Krawczyk, C. M.

10.1101/2023.05.28.542441 — immunology — Posted on 2023-06-07

3315 Considerations on brain age predictions from repeatedly sampled data across time

Korbmacher, M.; Wang, M.-Y.; Eikeland, R.; Buchert, R.; Andreassen, O. A.; Espeseth, T.; Leonardsen, E.; Westlye, L. T.; Maximov, I. I.; Specht, K.

10.1101/2023.03.31.535038 — neuroscience — Posted on 2023-06-08

3316 Modeling the 3D structure and conformational dynamics of very large RNAs using coarse-grained molecular simulations

Henderson, A. N.; McDonnell, R. T.; Elcock, A. H.

10.1101/2023.06.06.543892 — biophysics — Posted on 2023-06-08

3317 Active learning of the thermodynamics-dynamics tradeoff in protein condensates

An, Y.; Webb, M. A.; Jacobs, W. M.

10.1101/2023.06.06.543884 — biophysics — Posted on 2023-06-08

3318 Whole genome sequencing reveals autooctoploidy in the Chinese sturgeon and its evolutionary trajectories

10.1101/2023.06.06.543648 — genomics — Posted on 2023-06-07

3319 A ligation-independent sequencing method reveals tRNA-derived RNAs with blocked 3' termini

Scacchetti, A.; Shields, E. J.; Trigg, N. A.; Wilusz, J. E.; Conine, C. C.; Bonasio, R.

10.1101/2023.06.06.543899 — genomics — Posted on 2023-06-08

3320 Sequence and epigenetic landscapes of active and silenced nucleolus organizers in Arabidopsis

Fultz, D.; McKinlay, A.; Enganti, R.; Pikaard, C.

10.1101/2023.06.07.544131 — genomics — Posted on 2023-06-08

3321 Inferring disease architecture and predictive ability with LDpred2-auto

Prive, F.; Albinana, C.; Arbel, J.; Pasaniuc, B.; Vilhjalmsson, B. J.

10.1101/2022.10.10.511629 — genetics — Posted on 2023-06-08

3322 Catalytic activity of the Bin3/MEPCE methyltransferase domain is dispensable for 7SK snRNP function in Drosophila melanogaster

Palumbo, R. J.; Hanes, S. D.

10.1101/2023.06.01.543302 — genetics — Posted on 2023-06-08

3323 New resources for environmental genomics in the wild Mediterranean grass B. distachyon

Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.

10.1101/2023.06.01.543285 — ecology — Posted on 2023-06-08

3324 Spontaneous and inducible CD8 T cell lesions in the brain and spinal cord of HLA-DR15-positive MS PBMC humanized mice

Papazian, I.; Kourouvani, M.; Dagkonaki, A.; Dimitrakopoulou, L.; Gouzouasis, V.; Badounas, F.; Markoglou, N.; Belimezi, M.; Angelakis, E.; Tselios, T.; Anagnostouli, M.; Probert, L.

10.1101/2023.06.07.543414 — immunology — Posted on 2023-06-07

3325 PTP1B phosphatase puts a brake on iPSC-derived neutrophil motility and antimicrobial function

Giese, M.; Bennin, D.; Schoen, T. J.; Peterson, A.; Brand, J.; Jung, H. S.; Dinh, H.; Slukvin, I.; Huttenlocher, A.

10.1101/2023.06.05.543775 — immunology — Posted on 2023-06-07

3326 Investigation of Volatile Metabolites in Sebum as Prodromal Indicators of Parkinson's Disease

Walton-Doyle, C.; Heim, B.; Sinclair, E.; Hollywood, K.; Milne, J.; Holzknecht, E.; Stefani, A.; Hogl, B.; Seppi, K.; Silverdale, M.; Poewe, W.; Barran, P.; Trivedi, D. K.

10.1101/2023.03.01.530578 — neuroscience — Posted on 2023-06-08

3327 Cell Type Specific CAG Repeat Expansions and Toxicity of Mutant Huntingtin in Human Striatum and Cerebellum

Mätlik, K.; Baffuto, M.; Kus, L.; Deshmukh, A. L.; Davis, D. A.; Paul, M. R.; Carroll, T. S.; Caron, M.-C.; Masson, J.-Y.; Pearson, C. E.; Heintz, N.

10.1101/2023.04.24.538082 — neuroscience — Posted on 2023-06-08

3328 DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters

Pham, T. M.; Miffin, T.; Sun, H.; Sharp, K. K.; Wang, X.; Zhu, M.; Hoshika, S.; Peterson, R. J.; Benner, S. A.; Kahn, J. D.; Mathews, D.

10.1101/2023.06.06.543917 — biophysics — Posted on 2023-06-08

3329 Active density fluctuations in bacterial binary mixtures

Espada Burriel, S.; Colin, R.

10.1101/2023.05.10.540167 — biophysics — Posted on 2023-06-08

3330 COVFlow: performing virus phylodynamics analyses from selected SARS-CoV-2 genome sequences

Danesh, G.; Boennec, C.; Verdurme, L.; Roussel, M.; Trombert, S.; Visseaux, B.; Haim-Boukobza, S.; Alizon, S.

10.1101/2022.06.17.496544 — bioinformatics — Posted on 2023-06-08

3331 An R package for ensemble learning stacking

Nukui, T.; Onogi, A.

10.1101/2023.06.06.543970 — bioinformatics — Posted on 2023-06-08

3332 Haplotype-resolved, chromosome-level assembly of white clover (Trifolium repens L., Fabaceae)

Santangelo, J.; Battlay, P.; Hendrickson, B.; Kuo, W.-H.; Olsen, K. M.; Kooyers, N. J.; Johnson, M.; Hodgins, K.; Ness, R.

10.1101/2023.06.06.543960 — genomics — Posted on 2023-06-08

3333 Adaptation to seasonal reproduction and temperature-associated factors drive temporal and spatial differentiation in northwest Atlantic herring despite gene flow

Fuentes-Pardo, A. P.; Stanley, R.; Bourne, C.; Singh, R.; Emond, K.; Pinkham, L.; McDermid, J. L.; Andersson, L.; Ruzzante, D. E.

10.1101/578484 — genomics — Posted on 2023-06-08

3334 Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours

Grenko, C.; Bonnycastle, L. L.; Taylor, H. J.; Yan, T.; Swift, A. J.; Robertson, C. C.; Narisu, N.; Erdos, M. R.; Collins, F. S.; Taylor, D. L.

10.1101/2023.06.06.543931 — genetics — Posted on 2023-06-08

3335 Imaging the pharmacokinetics and therapeutic availability of the bispecific CD3xTRP1 antibody in syngeneic mouse tumor models

Sandker, G. G. W.; Middelburg, J.; Wilbrink, E.; Molkenboer-Kuenen, J.; Aarntzen, E.; van Hall, T.; Heskamp, S.

10.1101/2023.06.06.543829 — immunology — Posted on 2023-06-07

3336 Long-term cytotoxic NK cells with broad anti-tumour capacity proliferate selectively, without exhaustion, after BCG priming and extremely low doses of cytokines

Felgueres, M.-J.; Esteso, G.; Garcia-Jimenez, A.; Dopazo, A.; Martinez-Pineiro, L.; Reyburn, H. T.; Vales-Gomez, M.

10.1101/2023.06.07.543999 — immunology — Posted on 2023-06-07

3337 A Transfer Entropy-based methodology to analyze information flow under eyes-open and eyes-closed conditions with a clinical perspective

Restrepo, J. F.; Mateos, D. M.; Lopez, J. M. D.

10.1101/2022.12.20.521265 — neuroscience — Posted on 2023-06-08

3338 Evaluating the capabilities of the Astral mass analyzer for single-cell proteomics

Petrosius, V.; Aragon-Fernandez, P.; Arrey, T. N.; Uresin, N.; Furtwangler, B.; Stewart, H.; Denisov, E.; Petzoldt, J.; Peterson, A. C.; Hock, C.; Damoc, E.; Makarov, A.; Zabrouskov, V.; Porse, B. T.; Schoof, E. M.

10.1101/2023.06.06.543943 — systems biology — Posted on 2023-06-08

3339 Benefits and limits of biological nitrification inhibitors for plant N uptake and the environment

Kuppe, C. W.; Postma, J. A.

10.1101/2023.06.07.543901 — plant biology — Posted on 2023-06-08

3340 Cotyledon Peeling Method for Passion Fruit Protoplasts: a versatile cell system for transient gene expression in passion fruit (Passiflora edulis)

Wang, L.; Liu, H.; Liu, P.; Wu, G.; Shen, W.; Cui, H.; Dai, Z.

10.1101/2023.06.08.542798 — plant biology — Posted on 2023-06-08

3341 Presence of vitamin B12 metabolism in the last common ancestor of land plants

Dorrell, R. G.; Nef, C.; Altan-Ochir, S.; Bowler, C.; Smith, A. G.

10.1101/2023.06.07.544158 — plant biology — Posted on 2023-06-08

3342 Metabolic adaptations leading to lignification in wheat roots under salinity stress

Dissanayake, B. M.; Staudinger, C.; Ranathunge, K.; Munns, R.; Rupasinghe, T. W.; Taylor, N. L.; Millar, A. H.

10.1101/2023.06.08.544172 — plant biology — Posted on 2023-06-08

3343 Photo-physiological Acclimation in Synechocystis sp. PCC 6803 Provides Insight into Growth Limitation in Underwater Spectra

Zavrel, T.; Segecova, A.; Kovacs, L.; Lukes, M.; Novak, Z.; Szabo, M.; Somogyi, B.; Prasil, O.; Cerveny, J.; Bernat, G.

10.1101/2023.06.08.544187 — plant biology — Posted on 2023-06-08

3344 BKCa nitrosylation is associated with cerebral microvascular dysfunction in female 5x-FAD mice

da Silva, J. F.; Polk, F. D.; Savu, A.; Kath, A. M.; Gee, M. T.; Pires, P. W.

10.1101/2023.06.06.543962 — physiology — Posted on 2023-06-08

3345 Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy

Siricilla, S.; Hansen, C. J.; Rogers, J. H.; De, D.; Simpson, C. L.; Waterson, A. G.; Sulikowski, G. A.; Crockett, S. L.; Boatwright, N.; Reese, J. J.; Paria, B. C.; Newton, J. M.; Herington, J. L.

10.1101/2023.06.06.543921 — pharmacology and toxicology — Posted on 2023-06-08

3346 Neurobehavioral effects of fungicides in zebrafish: a systematic review and meta-analysis

Reis, C. G.; Bastos, L. M.; Chitolina, R.; Gallas-Lopes, M.; Zanona, Q. K.; Becker, S. Z.; Herrmann, A. P.; Piato, A.

10.1101/2023.06.06.543927 — pharmacology and toxicology — Posted on 2023-06-08

3347 MSModDetector: A Tool for Detecting Mass Shifts and Post-Translational Modifications in Individual Ion Mass Spectrometry Data

Faizi, M.; Fellers, R. T.; Lu, D.; Drown, B. S.; Jambhekar, A.; Lahav, G.; Kelleher, N. L.; Gunawardena, J.

10.1101/2023.06.06.543961 — bioinformatics — Posted on 2023-06-08

3348 Validation of de novo designed water-soluble and transmembrane proteins by in silico folding and melting

Martin, A.; Berner, C.; Ovchinnikov, S.; Vorobieva, A. A.

10.1101/2023.06.06.543955 — bioinformatics — Posted on 2023-06-08

3349 Discrete Multiwalled Carbon Nanotubes for Versatile Intracellular Transport of Functional Biomolecular Complexes

Castillo, K.; Tasset, A.; Marinkovic, M.; Foote, A.

10.1101/2023.06.06.543926 — bioengineering — Posted on 2023-06-08

3350 Genomes of historical specimens reveal multiple invasions of LTR retrotransposons in Drosophila melanogaster populations during the 19th century.

Scarpa, A.; Pianezza, R.; Wierzbicki, F.; Kofler, R.

10.1101/2023.06.06.543830 — evolutionary biology — Posted on 2023-06-08

3351 A comprehensive analysis of grazing: Improving management for environmental health

Niederman, T. E.; Xu, A. L.; Dreiss, L. M.

10.1101/2023.06.06.543944 — ecology — Posted on 2023-06-08

3352 Ontogenetic Patterns in Juvenile Blue Crab density: Effects of Habitat and Turbidity in a Chesapeake Bay Tributary

Hyman, A.; Chiu, G.; Seebo, M. S.; Smith, A.; Saluta, G.; Lipcius, R.

10.1101/2023.06.05.543724 — ecology — Posted on 2023-06-08

3353 Vgamma9+Vdelta2+Tcell-mediated purging of Listeria monocytogenes-infected epithelial cells requires butyrophilin 3A genes

Fischer, K.; Bradlerova, M.; Decker, T.; Supper, V.

10.1101/2023.06.07.544000 — immunology — Posted on 2023-06-07

3354 The zinc transporter Slc30a1 in macrophages plays a protective role against Salmonella infection

Na-Phatthalung, P.; Sun, S.; Xiao, E.; Wang, J.; Min, J.; Wang, F.

10.1101/2023.06.06.543958 — immunology — Posted on 2023-06-07

3355 Localized measurements of water potential reveal large loss of conductance in living tissues of maize leaves

Jain, P.; Huber, A. E.; Rockwell, F. E.; Sen, S.; Holbrook, N. M.; Stroock, A.

10.1101/2023.06.06.543905 — physiology — Posted on 2023-06-08

3356 Predicting genetically regulated gene expression on the X chromosome

Zhang, X.; Below, J.; Kunkle, B. W.; Martin, E.; Naj, A. C.; Bush, W.

10.1101/2023.06.06.543877 — bioinformatics — Posted on 2023-06-08

3357 OmicVerse: A single pipeline for exploring the entire transcriptome universe

Zeng, Z.; Ma, Y.; Hu, L.; Xiong, Y.; Du, H.

10.1101/2023.06.06.543913 — bioinformatics — Posted on 2023-06-08

3358 BOTTOM-UP EFFECTS AND DENSITY DEPENDENCE DRIVE THE DYNAMIC OF AN ANTARCTIC SEABIRD PREDATOR-PREY SYSTEM

Viollat, L.; Queroue, M.; Delors, K.; Gimenez, O.; Barbraud, C.

10.1101/2023.06.06.543885 — ecology — Posted on 2023-06-08

3359 Contrasting patterns of foraging behavior in Neotropical stingless bees using pollen and honey metabarcoding

Martins, A. C.; Proenca, C. E. B.; Vasconcelos, T. N. C.; Aguiar, A. J. C.; Farinasso, H. C.; Lima, A. T. F.; Faria, J. E. Q.; Norrana, K.; Costa, M. B. R.; Carvalho, M. M.; Dias, R. L.; Bustamante, M. M. C.; Carvalho, F. A.; Keller, A.

10.1101/2023.06.06.543880 — ecology — Posted on 2023-06-08

3360 Molecular Pixelation: Single cell spatial proteomics by sequencing

Karlsson, F.; Kallas, T.; Thiagarajan, D.; Karlsson, M.; Schweitzer, M.; Navarro, J. F.; Leijonancker, L.; Geny, S.; Pettersson, E.; Rhomberg-Kauert, J.; Granillo, M. G.; Bunz, J.; Dahlberg, J.; Simonetti, M.; Sathe, P.; Brodin, P.; Barrio, A. M.; Fredriksson, S.

10.1101/2023.06.05.543770 — immunology — Posted on 2023-06-08

3361 Non-self RNA rewires IFNβ signaling: A mathematical model of the innate immune response

Korwek, Z.; Czerkies, M.; Jaruszewicz-Blonska, J.; Prus, W.; Kosiuk, I.; Kochanczyk, M.; Lipniacki, T.

10.1101/2022.01.30.478391 — immunology — Posted on 2023-06-08

3362 Temporal Vascular Endothelial Growth Factor Sub-type gene Switching in SARS-CoV Pathogenesis. Interpretation through in vivo Murine C57BL Models

Rashid, A.; Benakatti, G.; Al-Obeidat, F.; Malik, Z. A.; Brierley, J.; Sharma, V.; Sharma, A.; Gupta, L.; Alkhazaimi, H.; Shaikh, G.; Al-Dubai, A.; Quraishi, N.; Zaki, S. A.; Wael Hafez, W.; Hussain, A.

10.1101/2022.11.06.515327 — immunology — Posted on 2023-06-08

3363 Activation of Multiple Eph Receptors on Neuronal Membranes Correlates with The Onset of Traumatic Optic Neuropathy

Strong, T. A.; Esquivel, J.; Wang, Q.; Ledon, P. J.; Wang, H.; Gaidosh, G.; Tse, D.; Pelaez, D.

10.1101/2023.06.05.543735 — neuroscience — Posted on 2023-06-07

3364 Single Nuclei RNA Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease

Pass, C. G.; Palzkill, V.; Tan, J.; Kim, K.; Thome, T.; Yang, Q.; Fazzone, B.; Robinson, S. T.; O'Malley, K.; Yue, F.; Scali, S. T.; Berceli, S. A.; Ryan, T. E.

10.1101/2023.06.05.543809 — genomics — Posted on 2023-06-07

3365 Midbrain encodes sound detection behavior without auditory cortex

Lee, T.-Y.; Weissenberger, Y.; King, A. J.; Dahmen, J. C.

10.1101/2023.06.07.544013 — neuroscience — Posted on 2023-06-07

3366 Visual activity enhances neuronal excitability in thalamic relay neurons

Dumenieu, M.; Fronzaroli-Molinieres, L.; Iborra-Bonnaure, C.; Wakade, A.; Zanin, E.; Aziz, A.; Ankri, N.; Incontro, S.; Denis, D.; Brette, R.; Marqueze-Pouey, B.; Debanne, D.; Russier, M.

10.1101/2023.06.06.543854 — neuroscience — Posted on 2023-06-07

3367 Developmental changes in individual alpha frequency: Recording EEG data during public engagement events

Turner, C.; Baylan, S.; Bracco, M.; Cruz, G.; Hanzal, S.; Keime, M.; Kuye, I.; McNeill, D.; Ng, Z.; van der Plas, M.; Ruzzoli, M.; Thut, G.; Trajkovic, J.; Veniero, D.; Wale, S. P.; Whear, S.; Learmonth, G.

10.1101/2023.01.20.524682 — neuroscience — Posted on 2023-06-08

3368 Integrative Multi-omic Profiling of Two Human Decedents Receiving Pig Heart Xenografts Reveals Strong Perturbations in Early Immune-Cell and Cellular Metabolism Responses.

Schmauch, E.; Piening, B. D.; Xia, B.; Zhu, C.; Stern, J.; Zhang, W.; Dowdell, A.; Loza, B.; Mohebnasab, M.; Gragert, L.; Khalil, K.; Camellato, B.; de Oliveira, M. F.; O'Brien, D.; Weldon, E.; Lin, X.; Gao, H.; Kagermazova, L.; Kim, J.; Loupy, A.; Heguy, A.; Taylor, S.; Zhu, F.; Gao, S.; Gandla, D.; Reddy, K.; Chang, A.; Michael, B.; Jiang, L.; Jian, R.; Narula, N.; Linna-Kuosmanen, S.; Kaikkonen-Maatta, M.; Lorber, M.; Kellis, M.; Tatapudi, V.; Ayares, D.; Griesemer, A.; Mangiola, M.; Pass, H.; Snyder, M. P.; Boeke, J. D.; Montgomery, R. A.; Keating, B. J.

10.1101/2023.06.05.543406 — systems biology — Posted on 2023-06-08

3369 Quantile Regression for biomarkers in the UK Biobank

Wang, C.; Wang, T.; Wei, Y.; Aschard, H.; Ionita-Laza, I.

10.1101/2023.06.05.543699 — genomics — Posted on 2023-06-07

3370 Strain-dependent effects on neurobehavioral and seizure phenotypes in Scn2aK1422E mice

Echevarria-Cooper, D. M.; Hawkins, N. A.; Kearney, J. A.

10.1101/2023.06.06.543929 — neuroscience — Posted on 2023-06-07

3371 Hippocampal Theta Phase Precession Supports Memory Formation and Retrieval of Naturalistic Experience in Humans

Zheng, J.; Yebra, M.; Schjetnan, A. G. P.; Mosher, C.; Kalia, S. K.; Chung, J. M.; Reed, C. M.; Valiante, T. A.; Mamelak, A. N.; Kreiman, G.; Rutishauser, U.

10.1101/2023.06.05.543539 — neuroscience — Posted on 2023-06-08

3372 Modulation of pore opening of Eukaryotic sodium channels by π-helices in S6

Choudhury, K.; Delemotte, L.

10.1101/2023.03.25.534196 — biophysics — Posted on 2023-06-08

3373 Structural and mechanistic insights into the MCM8/9 helicase complex

Weng, Z.; Zheng, J.; Zhou, Y.; Lu, Z.; Wu, Y.; Xu, D.; Li, H.; Liang, H.; Liu, Y.

10.1101/2022.01.26.477944 — biophysics — Posted on 2023-06-08

3374 SpLitteR: Diploid genome assembly using linked TELL-Seq reads and assembly graphs

Tolstoganov, I.; Chen, Z.; Pevzner, P. A.; Korobeynikov, A.

10.1101/2022.12.08.519233 — bioinformatics — Posted on 2023-06-08

3375 Structural variants and short tandem repeats impact gene expression and splicing in bovine testis tissue

Bhati, M.; Mapel, X. M.; Lloret-Villas, A.; Pausch, H.

10.1101/2023.06.07.543773 — genomics — Posted on 2023-06-07

3376 Prior experience with behavioral control over stress facilitates social dominance

Coleman, P. T.; Costanza-Chavez, G. W.; Martin, H. N.; Amat, J.; Frank, M. G.; Sanchez, R. J.; Potter, G. J.; Mellert, S. M.; Carter, R. K.; Bonnici, G. N.; Maier, S. F.; Baratta, M. V.

10.1101/2023.06.06.543982 — neuroscience — Posted on 2023-06-07

3377 A region-resolved proteomic map of the human brain enabled by high-throughput proteomics

Tüshaus, J.; Sakhteman, A.; Lechner, S.; The, M.; Mucha, E.; Krisp, C.; Schlegel, J.; Delbridge, C.; Küster, B.

10.1101/2023.06.05.543676 — neuroscience — Posted on 2023-06-08

3378 CDK4 phosphorylation status and rational use for combining CDK4/6 and BRAF/MEK inhibition in advanced thyroid carcinomas

Pita, J. M.; Raspe, E.; Coulonval, K.; Decaussin-Petrucci, M.; Tarabichi, M.; Dom, G.; Libert, F.; Craciun, L.; Andry, G.; Wicquart, L.; Leteurtre, E.; Tresallet, C.; Marlow, L. A.; Copland, J. A.; Durante, C.; Maenhaut, C.; Cavaco, B. M.; Dumont, J. E.; Costante, G.; Roger, P. P.

10.1101/2023.06.05.543656 — cancer biology — Posted on 2023-06-07

3379 Soluble CTLA-4 raises the threshold for T-cell activation and modulates anti-tumour immunity

Kennedy, P. T.; Saulters, E. L.; Duckworth, A. D.; Lim, Y. J.; Woolley, J. F.; Slupsky, J. R.; Cragg, M. S.; Ward, F. J.; Dahal, L. N.

10.1101/2023.06.05.543731 — cancer biology — Posted on 2023-06-07

3380 Differences in the regulation mechanisms of the glutamine synthetase from methanogenic archaea unveiled by structural investigations

Müller, M.-C.; Lemaire, O. N.; Kurth, J. M.; Welte, C. U.; Wagner, T.

10.1101/2023.04.07.535877 — biochemistry — Posted on 2023-06-08

3381 Using a P. falciparum genetic cross to dissect the relative contributions of pfcrt and plasmepsin II/III to piperaquine response-related traits

Kane, J.; Li, X.; Kumar, S.; Button-Simons, K. A.; Vendrely Brenneman, K.; Dahlhoff, H.; Sievert, M. A. C.; Checkley Needham, L. A.; Shoue, D.; Singh, P. P.; Haile, M. T.; Reyes, A.; Cheeseman, I. H.; Vaughan, A. M.; Anderson, T. J.; Ferdig, M. T.

10.1101/2023.06.06.543862 — genomics — Posted on 2023-06-07

3382 Pre-attentive representation of prediction certainty in autism: A mismatch negativity (MMN) study

Reisli, S.; Molholm, S.

10.1101/2023.06.06.543878 — neuroscience — Posted on 2023-06-07

3383 Translational approach to social isolation during a global pandemic: Hippocampal somatic mutation

Lee, B.; Seo, Y.; Jung, S.; Im, S.; Choi, H. J.; Bae, J. N.; Kim, Y.

10.1101/2023.06.06.542200 — neuroscience — Posted on 2023-06-07

3384 A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

Zaalberg, A.; Minnee, E.; Mayayo-Peralta, I.; Schuurman, K.; Gregoricchio, S.; van Schaik, T. A.; Hoekman, L.; Li, D.; Corey, E.; Janssen, H.; Lieftink, C.; Prekovic, S.; Altelaar, M.; Nelson, P. S.; Beijersbergen, R.; Zwart, W.; Bergman, A. M.

10.1101/2023.06.06.543873 — cancer biology — Posted on 2023-06-07

3385 Cancer initiation is influenced by sex-biased tissue environment or imbalanced hormones

Zhang, F.; Deng, M.

10.1101/2023.05.20.541565 — cancer biology — Posted on 2023-06-08

3386 Computational analysis of long-range allosteric communications in CFTR

Ersoy, A.; Altintel, B.; Livnat-Levanon, N.; Ben-Tal, N.; Haliloglu, T.; Lewinson, O.

10.1101/2023.06.07.543997 — biophysics — Posted on 2023-06-07

3387 Sequence and epigenetic landscapes of active and silenced nucleolus organizers in Arabidopsis

Fultz, D.; McKinlay, A.; Enganti, R.; Pikaard, C.

10.1101/2023.06.07.544131 — genomics — Posted on 2023-06-07

3388 Segmental Duplications Drive the Evolution of Accessory Regions in a Major Crop Pathogen

van Westerhoven, A.; Aguilera-Galvez, C.; Nakasato-Tagami, G.; Shi-Kunne, X.; Dijkstra, J.; Martinez de la Parte, E.; Chavarro Carero, E.; Meijer, H.; Feurtey, A.; Maryani, N.; Ordonez, N.; Hofstede, R.; Wittenberg, A.; Sorensen, A.; Garcia-Bastidas, F.; Schneider, H.; Nijbroek, K.; Stukenbrock, E.; Kema, G.; Seidl, M.

10.1101/2023.06.07.544053 — genomics — Posted on 2023-06-07

3389 Precision RNAi using synthetic shRNAmir target sites

Hoffmann, T.; Hörmann, A.; Corcokovic, M.; Zmajkovic, J.; Hinterndorfer, M.; Salkanovic, J.; Spreitzer, F.; Köferle, A.; Gitschtaler, K.; Popa, A.; Oberndorfer, S.; Andersch, F.; Schaefer, M.; Fellner, M.; Budano, N.; Ruppert, J. G.; Chetta, P.; Wurm, M.; Zuber, J.; Neumüller, R. A.

10.1101/2022.11.24.517802 — genetics — Posted on 2023-06-07

3390 Continuous Measures of Decision-Difficulty Captured Remotely: I. Mouse-tracking sensitivity extends to tablets and smartphones

Zuk, A. A. O.; Bertrand, J. K.; Chapman, C. S.

10.1101/2023.06.06.543796 — neuroscience — Posted on 2023-06-07

3391 Lesion Network Localization of a Stable Personality Trait

Palm, S.; Khosravani, S.; Campanella, F.; Cohen, A. L.; Drew, W.; Fabbro, F.; Pottanat, R.; Urgesi, C.; Ferguson, M. A.; Siddiqi, S. H.

10.1101/2023.06.05.543261 — neuroscience — Posted on 2023-06-07

3392 The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics

Yee, S. W.; Macdonald, C.; Mitrovic, D.; Zhou, X.; Koleske, M.; Yang, J.; Silva, D. B.; Grimes, P. R.; Trinidad, D.; More, S. S.; Kachuri, L.; Witte, J. S.; Delemotte, L.; Giacomini, K. M.; Coyote-Maestas, W.

10.1101/2023.06.06.543963 — biophysics — Posted on 2023-06-07

3393 The Genetic Architecture of Dietary Iron Overload and Associated Pathology in Mice

Fuqua, B. K.; Moses, L.; McLachlan, S.; Pan, C.; Davis, R. C.; Hui, S. T.; Che, N.; Zhou, Z.; Ng, C.; Charugundla, S.; Blencowe, M.; Saleem, Z.; Miikeda, A.; Ozdemir, B.; Hui, C.; Li, T.; Stolin, C. L.; Kozuch, M.; Zhou, J.; Page, K.; Irimagawa, H.; Ku, N.; Taraszka, K.; LaPierre, N.; Killilea, D. W.; Frazer, D. M.; Yang, X.; Eskin, E.; Vulpe, C. D.; Lusis, A. J.

10.1101/2023.06.05.543764 — genetics — Posted on 2023-06-07

3394 Ancient DNA reveals the origins of the Albanians

Davranoglou, L. R.; Aristodemou, A.; Wesolowski, D.; Heraclides, A.

10.1101/2023.06.05.543790 — genetics — Posted on 2023-06-07

3395 Tropical origin, global diversification and dispersal in the pond damselflies (Coenagrionoidea) revealed by a new molecular phylogeny

Willink, B.; Ware, J.; Svensson, E. I.

10.1101/2022.01.21.477207 — evolutionary biology — Posted on 2023-06-08

3396 Mannose is crucial for mesoderm specification and symmetry breaking in gastruloids

dingare, C.; Yang, J.; Steventon, B.

10.1101/2023.06.05.543730 — developmental biology — Posted on 2023-06-08

3397 Evaluation of abstract rule-based associations in the human premotor cortex during passive observation

Gharesi, N.; Luneau, L.; Kalaska, J. F.; Baillet, S.

10.1101/2023.06.06.543581 — neuroscience — Posted on 2023-06-07

3398 The intra-individual reliability of 1H-MRS measurement in the anterior cingulate cortex across one year

Wang, M.-Y.; Korbmacher, M.; Eikland, R.; Craven, A. R.; Specht, K.

10.1101/2023.06.07.544020 — neuroscience — Posted on 2023-06-07

3399 PySilSub: An open-source Python toolbox for implementing the method of silent substitution in vision and nonvisual photoreception research

Martin, J. T.; Boynton, G. M.; Baker, D. H.; Wade, A. R.; Spitschan, M.

10.1101/2023.03.30.533110 — neuroscience — Posted on 2023-06-08

3400 Cleaving DNA with DNA: cooperative tuning of structure and reactivity driven by copper ions

Dantu, S. C.; Khalil, M.; Bria, M.; Saint-Pierre, C.; Gasparutto, D.; Sicoli, G.

10.1101/2023.06.06.543833 — biophysics — Posted on 2023-06-08

3401 Rare coding variants in NOX4 link high superoxide levels to psoriatic arthritis mutilans

Wang, S.; Nikamo, P.; Laasonen, L.; Gudbjornsson, B.; Ejstrup, L.; Iversen, L.; Lindqvist, U.; Alm, J. J.; Eisfeldt, J.; Zheng, X.; Catrina, S.-B.; Taylan, F.; Vaz, R.; Stahle, M.; Tapia-Paez, I.

10.1101/2023.06.06.543425 — genetics — Posted on 2023-06-07

3402 Distinct subtypes of grey matter heterotopia show subtype-specific morpho-electric neuronal properties and dynamics of epileptiform activity in mice

Vermoyal, J.-C.; Hardy, D.; Goirand-Lopez, L.; Vinck, A.; Silvagnoli, L.; Fortoul, A.; Francis, F.; Cappello, S.; Bureau, I.; Represa, A.; Cardoso, C.; Watrin, F.; Marissal, T.; Manent, J.-B.

10.1101/2023.06.06.543853 — neuroscience — Posted on 2023-06-07

3403 Pathway-specific progression of Tau pathology in the human thalamus

Sarkany, B.; David, C.; Hortobagyi, T.; Gombas, P.; Somogyi, P.; Acsady, L. J.; Viney, T. J.

10.1101/2023.06.05.543738 — neuroscience — Posted on 2023-06-07

3404 Hypergravity is more challenging than microgravity for the human sensorimotor system

Chomienne, L.; Sainton, P.; Sarlegna, F. R.; Bringoux, L.

10.1101/2021.12.08.471552 — neuroscience — Posted on 2023-06-08

3405 Broaden the application of Yarrowia Lipolytica synthetic biology tools to explore the potential of Yarrowia clade biodiversity

Park, Y.-K.; Rossignol, T.

10.1101/2023.06.05.543681 — synthetic biology — Posted on 2023-06-08

3406 Human sodium current voltage-dependence at physiological temperature measured by coupling patch-clamp experiment to a mathematical model.

Abrasheva, V. O.; Kovalenko, S. G.; Slotvitsky, M.; Scherbina, S. A.; Aitova, A. A.; Frolova, S.; Tsvelaya, V. A.; Syunyaev, R.

10.1101/2023.06.06.543894 — biophysics — Posted on 2023-06-07

3407 Enhanced muscle regeneration in mdx mice, Duchenne muscular dystrophy animal model, proven by CD44 & MYH3 expression, on oral feeding of N-163 strain of Aureobasidium Pullulans produced B-Glucan

Preethy, S.; Sakamoto, S.; Higuchi, T.; Ichiyama, K.; Yamamoto, N.; Ikewaki, N.; Iwasaki, M.; Dedeepiya, V. D.; Srinivasan, S.; Rajmohan, M.; Senthilkumar, R.; Abraham, S. J.

10.1101/2023.06.06.543858 — genetics — Posted on 2023-06-07

3408 Boundary Bypass Activity in the Abdominal-B Region of the Drosophila Bithorax Complex is Position Dependent and Regulated

Kyrchanova, O.; Ibragimov, A.; Postika, N.; Georgiev, P.; Schedl, P.

10.1101/2023.06.06.543971 — genetics — Posted on 2023-06-07

3409 Autonomous and non-cell autonomous etiology of ciliopathy associated structural birth defects

Francis, R. J.; San Agustin, J. T.; Szabo Rogers, H. L.; Cui, C.; Jonassen, J. A.; Eguether, T.; Follit, J. A.; Lo, C. W.; Pazour, G.

10.1101/2023.06.07.544132 — developmental biology — Posted on 2023-06-07

3410 Parkinson's VPS35 mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B

Pal, P.; Taylor, M.; Lam, P. Y.; Tonelli, F.; Hecht, C. A.; Lis, P.; Nirujogi, R. S.; Phung, T. K.; Dickie, E. A.; Wightman, M.; Macartney, T.; Pfeffer, S. R.; Alessi, D. R.

10.1101/2023.06.07.544051 — neuroscience — Posted on 2023-06-07

3411 The canonical stopping network: Revisiting the role of the subcortex in response inhibition

Isherwood, S. J. S.; Kemp, S.; Miletic, S.; Stevenson, N.; Bazin, P.-L.; Forstmann, B.

10.1101/2023.06.06.543900 — neuroscience — Posted on 2023-06-07

3412 Imidacloprid disrupts larval molting regulation and nutrient energy metabolism, causing developmental delay in honey bee Apis mellifera

Li, Z.; Wang, Y.; Qin, Q.; Chen, L.; Dang, X.; Ma, Z.; Zhou, Z.

10.1101/2023.06.05.543803 — zoology — Posted on 2023-06-07

3413 Understanding early reproductive failure in turtles and tortoises

Lavigne, A. M.; Bullock, R.; Shah, N. J.; Tagg, C.; Zora, A.; Hemmings, N.

10.1101/2023.06.07.544015 — zoology — Posted on 2023-06-07

3414 Limiting Pool and Actin Architecture Controls Myosin Cluster Sizes in Adherent Cells

Chou, W.-h.; Molaei, M.; Wu, H.; Oakes, P. W.; Beach, J.; Gardel, M.

10.1101/2023.06.07.544121 — biophysics — Posted on 2023-06-07

3415 Transcription factor FfmA interacts both physically and genetically with AtrR to properly regulate gene expression in the fungus Aspergillus fumigatus

Paul, S.; Stamnes, M. A.; Moye-Rowley, W. S.

10.1101/2023.06.06.543935 — genetics — Posted on 2023-06-07

3416 Expression and molecular regulation of key genes during adipogenesis of neural crest stem cells

Dong, B.; Guan, W.-c.; Zhang, K.; Zhang, Y.; Yang, Y.; Zhao, Y.-p.; Bai, R.; Zheng, M.-x.; Cui, X.

10.1101/2023.06.07.544147 — developmental biology — Posted on 2023-06-07

3417 Metabolic regulation in erythroid differentiation by systemic ketogenesis in fasted mice

Ma, W.; Arima, Y.; Umemoto, T.; Yokomizo, T.; Xu, Y.; Miharada, K.; Tanaka, Y.; Suda, T.

10.1101/2023.06.07.544102 — cell biology — Posted on 2023-06-07

3418 Continuous Measures of Decision-Difficulty Captured Remotely: II. Webcam eye-tracking reveals early decision processing

Bertrand, J. K.; Zuk, A. A. O.; Chapman, C. S.

10.1101/2023.06.06.543799 — neuroscience — Posted on 2023-06-07

3419 Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury

Todd, B. P.; Luo, Z.; Gilkes, N.; Chimenti, M. S.; Peterson, Z.; Mix, M.; Harty, J. T.; Nickl-Jockschat, T.; Ferguson, P. J.; Bassuk, A. G.; Newell, E. A.

10.1101/2023.06.06.543774 — neuroscience — Posted on 2023-06-07

3420 Estimating individuals' exposure to predation risk in group-living baboons, Papio anubis

Suire, A.; Kunita, I.; Harel, R.; Crofoot, M.; Mutinda, M.; Kamau, M.; Hassel, J. M.; Murray, S.; Matsumoto-Oda, A.

10.1101/2023.06.06.543865 — zoology — Posted on 2023-06-07

3421 Understanding the General Principles of T Cell Engagement by Multiscale Computational Simulations

Su, Z.; Almo, S.; Wu, Y.

10.1101/2023.06.07.544116 — biophysics — Posted on 2023-06-07

3422 Quantifying turgor pressure in budding and fission yeasts based upon osmotic properties

LEMIERE, J.; Chang, F.

10.1101/2023.06.07.544129 — biophysics — Posted on 2023-06-07

3423 ATP binding cassette transporters and uridine diphosphate glycosyltransferases are ancient protein families that evolved roles in herbicide resistance through exaptation

Caygill, S.; Dolan, L.

10.1101/2023.06.06.543864 — evolutionary biology — Posted on 2023-06-07

3424 Anoctamin-1 is induced by TGF-beta and contributes to lung myofibroblast differentiation

Reed, E. B.; Orbeta, S.; Sitikov, A.; Levitan, I.; Mutlu, G. M.; Mongin, A. A.; Dulin, N. O.

10.1101/2023.06.07.544093 — cell biology — Posted on 2023-06-07

3425 Social reward network connectivity differs between autistic and neurotypical youth during social interaction

Xie, H.; Moraczewski, D.; McNaughton, K. R.; Warnell, K. R.; Alkire, D. R.; Merchant, J. S.; Kirby, L. A.; Yarger, H. A.; Redcay, E.

10.1101/2023.06.05.543807 — neuroscience — Posted on 2023-06-07

3426 Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes

Trotti, D.; Nelson, A. T.; Cicardi, M. E.; ShamamandriMarkandaiah, S.; Han, J.; Philp, N. J.; Welebob, E.; Haeusler, A.; Pasinelli, P.; Manfredi, G.; Kawamata, H.

10.1101/2023.06.07.544100 — neuroscience — Posted on 2023-06-07

3427 An updated end-to-end ecosystem model of the Northern California Current reflecting ecosystem changes due to recent marine heat waves

Gomes, D.; Ruzicka, J. J.; Crozier, L. G.; Huff, D. D.; Phillips, E. M.; Hernvann, P.-Y.; Morgan, C. A.; Brodeur, R. D.; Zamon, J. E.; Daly, E. A.; Bizzarro, J. J.; Fisher, J. L.; Auth, T. D.

10.1101/2022.12.28.522165 — systems biology — Posted on 2023-06-07

3428 Engineering cell and nuclear morphology on nano topography by contact-free protein micropatterning

Sarikhani, E.; Pushpa Meganathan, D.; Rahmani, K.; Tsai, C.-T.; Marquez-Serrano, A.; Li, X.; Santoro, F.; Cui, B.; Hyldgaard Klausen, L.; Jahed, Z.

10.1101/2023.06.05.543791 — biophysics — Posted on 2023-06-07

3429 The Multifaceted Effects of Short-Term Acute Hypoxia Stress: Insights into the tolerance mechanism of Propsilocerus akamusi (Diptera: Chironomidae)

zhang, y.; Zhang, Q.-J.; Xu, W.; Zou, W.; Xiang, X.; Gong, Z.; Cai, Y.

10.1101/2023.06.05.543801 — biophysics — Posted on 2023-06-07

3430 Approximate Bayesian computational methods to estimate the strength of divergent selection in population genomics models

Lukaszewicz, M.; Issaka Salia, O.; Hohenlohe, P. A.; Buzbas, E. O.

10.1101/2023.06.06.543823 — evolutionary biology — Posted on 2023-06-07

3431 Unpredictable soil conditions affect the prevalence of a microbial symbiosis

Scott, T. J.; Stephenson, C. J.; Rao, S.; Queller, D.; Strassmann, J. E.

10.1101/2023.06.07.543465 — evolutionary biology — Posted on 2023-06-07

3432 Homo- and heterodimerization of bHLH transcription factors balance stemness and bipotential differentiation

Puig-Barbe, A.; Nirello, V. D.; Azami, S.; Edgar, B. A.; Varga-Weisz, P.; Korzelius, J.; de Navascues, J.

10.1101/685347 — developmental biology — Posted on 2023-06-07

3433 The Neonatal Gyrencephalic Cortex Maintains Regionally Distinct Streams of Neuroblasts

Kim, J.; Sandoval, K.; Poddar, A.; Chu, J.; Horton, E.; Cui, D.; Nakamura, K.; Bartels, T.; Wood, C.; Rowitch, D. H.; Kim, H.; Sherwood, C. C.; Kramer, B. W.; Roberts, A. C.; ROSS, P. J.; Xu, D.; Robertson, N. J.; Ji, P.; Maga, E. A.; Paredes, M. F.

10.1101/2023.06.06.543768 — neuroscience — Posted on 2023-06-07

3434 Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition

Alegre Zurano, L.; Caceres-Rodriguez, A.; Berbegal-Saez, P.; Lassalle, O.; MANZONI, O. J.; Valverde, O.

10.1101/2023.06.05.543789 — neuroscience — Posted on 2023-06-07

3435 Mesostriatal dopamine is sensitive to specific cue-reward contingencies

Garr, E.; Cheng, Y.; Jeong, H.; Brooke, S.; Castell, L.; Bal, A.; Magnard, R.; Namboodiri, V. M. K.; Janak, P. H.

10.1101/2023.06.05.543690 — neuroscience — Posted on 2023-06-07

3436 Developmental hourglass: Confirmation by numerical evolution and elucidation by dynamical-systems theory

Kohsokabe, T.; Kuratani, S.; Kaneko, K.

10.1101/2023.06.05.542718 — systems biology — Posted on 2023-06-07

3437 Effects of sequence-dependent non-native interactions in equilibrium and kinetic folding properties of knotted proteins

Faisca, P. F.; Especial, J. N.

10.1101/2023.06.06.543861 — biophysics — Posted on 2023-06-07

3438 Cleaving DNA with DNA: cooperative tuning of structure and reactivity driven by copper ions

Dantu, S. C.; Khalil, M.; Bria, M.; Saint-Pierre, C.; Gasparutto, D.; Sicoli, G.

10.1101/2023.06.06.543833 — biophysics — Posted on 2023-06-07

3439 Mapping Protein Dynamics at High-Resolution with Temperature-Jump X-ray Crystallography

Wolff, A. M.; Nango, E.; Young, I. D.; Brewster, A. S.; Kubo, M.; Nomura, T.; Sugahara, M.; Owada, S.; Barad, B. A.; Ito, K.; Bhowmick, A.; Carbajo, S.; Hino, T.; Holton, J. M.; Im, D.; O'Riordan, L. J.; Tanaka, T.; Tanaka, R.; Sierra, R. G.; Yumoto, F.; Tono, K.; Iwata, S.; Sauter, N. K.; Fraser, J. S.; Thompson, M. C.

10.1101/2022.06.10.495662 — biophysics — Posted on 2023-06-07

3440 NEUROeSTIMator: Using Deep Learning to Quantify Neuronal Activation from Single-Cell and Spatial Transcriptomic Data

Bahl, E.; Chatterjee, S.; Mukherjee, U.; Elsadany, M.; Vanrobaeys, Y.; Lin, L.-C.; McDonough, M.; Resch, J.; Giese, K. P.; Abel, T.; Michaelson, J.

10.1101/2022.04.08.487573 — bioinformatics — Posted on 2023-06-07

3441 SEL1L-HRD1 interaction is prerequisite for the formation of a functional HRD1 ERAD complex

Lin, L. L.; Wei, X.; Wang, H. H.; Pederson, B.; Torres, M.; Lu, Y.; Li, Z. J.; Liu, X.; Mao, H.; Wang, H.; Zhao, Z.; Sun, S. E.; Qi, L.

10.1101/2023.04.13.536796 — biochemistry — Posted on 2023-06-07

3442 Comprehensive Characterization of tRNA by Ultra High-Performance Liquid Chromatography High-Resolution Accurate Mass Spectrometry

Ross, R. L.; Cowley, R.; Murphy, K.; Gamez, R.; Gazis, P.; Sutton, J.; Du, M.

10.1101/2023.06.07.544034 — biochemistry — Posted on 2023-06-07

3443 Detailed Survey of an in-vitro Intestinal Epithelium Model by Single-Cell Transcriptomics

Ran, R.; Munoz, J.; Jena, S.; Green, L.; Brubaker, D.

10.1101/2023.05.23.541940 — cell biology — Posted on 2023-06-07

3444 Cell size contributes to single-cell proteome variation

Lanz, M. C.; Fuentes Valenzuela, L.; Elias, J. E.; Skotheim, J. M.

10.1101/2022.10.17.512548 — cell biology — Posted on 2023-06-07

3445 The effect of estimation time window length on overlap correction in EEG data

Skukies, R. S.; Ehinger, B.

10.1101/2023.06.05.543689 — neuroscience — Posted on 2023-06-07

3446 Localized and global computation for integrating prior value and sensory evidence in the mouse cerebral cortex

Ishizu, K.; Nishimoto, S.; Funamizu, A.

10.1101/2023.06.06.543645 — neuroscience — Posted on 2023-06-07

3447 Single-nucleus RNA-sequencing reveals oligodendrocytes and their progenitors as vulnerable cell types in prefrontal cortex and anterior cingulate of brains with Parkinson's disease

Dehestani, M.; Blauwendraat, C.; Gasser, T.; Bansal, V.

10.1101/2023.05.11.540329 — neuroscience — Posted on 2023-06-07

3448 Force tuning explains changes in phasic dopamine signaling during stimulus-reward learning

Bakhurin, K. I.; Hughes, R. N.; Jiang, Q.; Hossain, M.; Gutkin, B.; Fallon, I. P.; Yin, H.

10.1101/2023.04.23.537994 — neuroscience — Posted on 2023-06-07

3449 A class of secreted mammalian peptides with potential to expand cell-cell communication

Wiggenhorn, A. L.; Abuzaid, H. Z.; Coassolo, L.; Li, V. L.; Tanzo, J. T.; Wei, W.; Lyu, X.; Svensson, K. J.; Long, J. Z.

10.1101/2023.06.02.543503 — physiology — Posted on 2023-06-07

3450 Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology

Heitmann, S.; Vandenberg, J. I.; Hill, A. P.

10.1101/2023.04.19.537441 — pharmacology and toxicology — Posted on 2023-06-07

3451 Biased activation of the vasopressin V2 receptor probed by NMR, paramagnetic ligands, and molecular dynamics simulations

Gaibelet, G.; Fouillen, A.; Stephanie, R.; Orcel, H.; Mendre, C.; Kanso, A.; Lanotte, R.; Nguyen, J.; Dimon, J.; Urbach, S.; Sounier, R.; Granier, S.; Bonnet, D.; Cong, X.; Mouillac, B.; Demene, H.

10.1101/2023.06.06.543947 — biophysics — Posted on 2023-06-07

3452 Gene model correction for PVRIG in single cell and bulk sequencing data enables accurate detection and study of its functional relevance

Nemzer, S.; Sabath, N.; Wool, A.; Alteber, Z.; Ando, H.; Nickles-Fader, A.; Wang, T.-L.; Shih, I.-M.; Pardoll, D. M.; Ganguly, S.; Turpaz, Y.; Levine, Z.; Granit, R. Z.

10.1101/2022.11.02.514879 — bioinformatics — Posted on 2023-06-07

3453 Impact of Point Mutation on Shiga-like Toxin 1: A Molecular Dynamics Simulation Study

Tabassum, N.; Paul, B. R.; Saddam, M.; Helal, M. M. U.; Paul, S.

10.1101/2023.06.07.544092 — bioinformatics — Posted on 2023-06-07

3454 Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control

Mahata, B.; Cabrera, A.; Brenner, D. A.; Guerra-Resendez, R. S.; Li, J.; Goell, J.; Wang, K.; Guo, Y.; Escobar, M.; Parthasarathy, A. K.; Szadowski, H.; Bedford, G.; Reed, D.; Hilton, I. B.

10.1101/2022.03.21.485228 — bioengineering — Posted on 2023-06-07

3455 Combined workflow for XL-MS data processing: Application to the FtsH-HflK-HflC membrane protein complex

Akkulak, H.; Goc, G.; Ince, H. K.; Kabasakal, B. V.; Ozcan, S.

10.1101/2023.06.07.544024 — biochemistry — Posted on 2023-06-07

3456 Nest traits for the world's birds

Sheard, C.; Street, S. E.; Healy, S. D.; Troisi, C. A.; Clark, A. D.; Yovcheva, A.; Trebaol, A.; Vanadzina, K.; Lala, K. N.

10.1101/2023.06.06.543860 — evolutionary biology — Posted on 2023-06-07

3457 Scattered differentiation of unlinked loci across the genome underlines ecological divergence of the selfing grass Brachypodium stacei

Mu, W.; Li, K.; Yang, Y.; Liu, J.; Nevo, E.; Catalan, P.

10.1101/2023.06.06.543844 — evolutionary biology — Posted on 2023-06-07

3458 The effectiveness of selection in a species affects the direction of amino acid frequency evolution

McShea, H.; Weibel, C.; Wehbi, S.; James, J. E.; Masel, J.

10.1101/2023.02.01.526552 — evolutionary biology — Posted on 2023-06-07

3459 Machine vision reveals micronucleus rupture as a potential driver of the transcriptomic response to aneuploidy

DiPeso, L.; Pendyala, S.; Huang, H. Z.; Fowler, D. M.; Hatch, E. M.

10.1101/2023.05.04.539483 — cell biology — Posted on 2023-06-07

3460 Multistability in neural systems with random cross-connections

Breffle, J.; Mokashe, S.; Qiu, S.; Miller, P.

10.1101/2023.06.05.543727 — neuroscience — Posted on 2023-06-07

3461 Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery

Sundaram, R. V. K.; Chatterjee, A.; Bera, M.; Grushin, K.; Panda, A.; Li, F.; Coleman, J.; Ramakrishnan, S.; Ernst, A.; Gupta, K.; Rothman, J. E.; Krishnakumar, S. S.

10.1101/2023.06.05.543781 — neuroscience — Posted on 2023-06-07

3462 Autism- and epilepsy-associated EEF1A2 mutations lead to translational dysfunction and altered actin bundling

Mohamed, M. S.; Klann, E.

10.1101/2023.06.06.543912 — neuroscience — Posted on 2023-06-07

3463 A marmoset brain cell census reveals influence of developmental origin and functional class on neuronal identity

Krienen, F. M.; Levandowski, K. M.; Zaniewski, H.; del Rosario, R. C.; Schroeder, M. E.; Goldman, M.; Wienisch, M.; Lutservitz, A.; Beja-Glasser, V. F.; Chen, C.; Zhang, Q.; Chan, K. Y.; Li, K. X.; Sharma, J.; McCormack, D.; Shin, T. W.; Harrahill, A.; Mauermann, A.; Wysoker, A.; Nemesh, J.; Kashin, S.; Vergara, J.; Chelini, G.; Dimidschstein, J.; Berretta, S.; Deverman, B. E.; Boyden, E.; McCarroll, S. A.; Feng, G.

10.1101/2022.10.18.512442 — neuroscience — Posted on 2023-06-07

3464 Fear in action: Fear conditioning and alleviation through body movements

Alemany Gonzalez, M.; Wokke, M. E.; Chiba, T.; Narumi, T.; Kaneko, N.; Yokoyama, H.; Watanabe, K.; Nakazawa, K.; Imamizu, H.; Koizumi, A.

10.1101/2022.06.20.496915 — neuroscience — Posted on 2023-06-07

3465 One thousand samples per day capillary-flow LC/MS/MS for high-speed, high-sensitivity and in-depth proteomics

Tomioka, A.; Tomioka, R.; Mori, I.; Isobe, Y.; Arita, M.; Imami, K.; Kanao, E.; Ogata, K.; Ishihama, Y.

10.1101/2023.06.05.543682 — systems biology — Posted on 2023-06-07

3466 Temporal analysis of relative distances (TARDIS) is a robust, parameter-free alternative to single-particletracking

Martens, K. J. A.; Turkowyd, B.; Hohlbein, J.; Endesfelder, U.

10.1101/2023.06.07.544011 — biophysics — Posted on 2023-06-07

3467 Analysis of Protein-Protein Interactions networks and cross-species transfer learning comparison for seven organisms

Martins, Y. C.

10.1101/2023.06.05.543725 — bioinformatics — Posted on 2023-06-07

3468 dsRID: Editing-free in silico identification of dsRNA region using long-read RNA-seq data

Yamamoto, R.; Liu, Z.; Choundhury, M.; Xiao, X.

10.1101/2023.06.02.543466 — bioinformatics — Posted on 2023-06-07

3469 Identification and functional analysis of novel stress-resistance genes from metagenomes of extreme environments

Juarez, J. H.; do Nascimento Silva, E.; Silva, N. H.; Silva-Rocha, R.; Guazzaroni, M. E.

10.1101/2023.06.07.544099 — bioengineering — Posted on 2023-06-07

3470 Broca's area, variation and taxic diversity in early Homo from Koobi Fora (Kenya)

Beaudet, A.; de Jager, E.

10.1101/2023.06.05.543693 — evolutionary biology — Posted on 2023-06-07

3471 A diversity of diversities: evaluating the relationships between below and aboveground biodiversity

Seaton, F. M.; George, P. B.; Jones, D. L.; Creer, S.; Alison, J.; Smart, S. M.; Emmett, B.; Robinson, D. A.

10.1101/2023.06.07.544003 — ecology — Posted on 2023-06-07

3472 Recall tempo of Hebbian sequences depends on the interplay of Hebbian kernel with tutor signal timing

Farrell, M.; Pehlevan, C.

10.1101/2023.06.07.542926 — neuroscience — Posted on 2023-06-07

3473 Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for normal breathing and chemosensory reflexes

Chang, Y.; Lusk, S.; Ray, R.

10.1101/2023.04.16.535729 — neuroscience — Posted on 2023-06-07

3474 Time for What? Dissociating Explicit Timing Tasks Through Electrophysiological Signatures

Bueno, F. D.; Nobre, A. C.; Cravo, A. M.

10.1101/2023.06.07.543718 — neuroscience — Posted on 2023-06-07

3475 SPIDR: a highly multiplexed method for mapping RNA-protein interactions uncovers a potential mechanism for selective translational suppression upon cellular stress

Wolin, E.; Guo, J. K.; Blanco, M. R.; Perez, A. A.; Goronzy, I. N.; Abdou, A. A.; Gorhe, D.; Guttman, M.; Jovanovic, M.

10.1101/2023.06.05.543769 — systems biology — Posted on 2023-06-07

3476 Bench-ML: A Benchmarking Web Interface for Machine Learning Methods and Models in Genomics

Lopez, R.; Makita, M.; Ortega, L.; Lal, A.; De la Garza, H.

10.1101/2023.06.05.543750 — bioinformatics — Posted on 2023-06-07

3477 Transfer Learning Enhanced Graph Neural Network for Aldehyde Oxidase Metabolism Prediction and Its Experimental Application

Xiong, J.; Cui, R.; Li, Z.; Zhang, W.; Zhang, R.; Fu, Z.; Liu, X.; Li, Z.; Chen, K.; Zheng, M.

10.1101/2023.06.05.543711 — bioinformatics — Posted on 2023-06-07

3478 Multiple sex chromosomes of Yponomeuta ermine moths suggest a role of sexual antagonism in sex chromosome turnover in Lepidoptera

Provaznikova, I.; Dalikova, M.; Volenikova, A.; Roessingh, P.; Sahara, K.; Provaznik, J.; Marec, F.; Nguyen, P.

10.1101/2023.06.06.543653 — evolutionary biology — Posted on 2023-06-07

3479 Plant geographic distribution influences chemical defenses in native and introduced Plantago lanceolata populations

Medina van Berkum, P.; Schmoeckel, E.; Bischoff, A.; Carrasco-Farias, N.; Catford, J. A.; Feldmann, R.; Groten, K.; Henry, H. A. L.; Lampei Bucharova, A.; Haenniger, S.; Luong, J. C.; Meis, J.; Oetama, V. S. P.; Paertel, M.; Power, S. A.; Villellas, J.; Welk, E.; Wingler, A.; Rothe, B.; Gershenzon, J.; Reichelt, M.; Roscher, C.; Unsicker, S. B.

10.1101/2023.06.05.543708 — ecology — Posted on 2023-06-07

3480 DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates

Mueller, S. A. L.; Oler, J. A.; Roseboom, P. H.; Aggarwal, N.; Kenwood, M. M.; Riedel, M. K.; Elam, V. R.; Olsen, M. E.; DiFilippo, A. H.; Christian, B. T.; Hu, X.; Galvan, A.; Boehm, M. A.; Michaelides, M.; Kalin, N. H.

10.1101/2023.06.06.543911 — neuroscience — Posted on 2023-06-07

3481 The Time-Course of Food Representation in the Human Brain

Moerel, D.; Psihoyos, J.; Carlson, T. A.

10.1101/2023.06.06.543985 — neuroscience — Posted on 2023-06-07

3482 The curse of optimism: a persistent distraction by novelty

Modirshanechi, A.; Lin, W.-H.; Xu, H. A.; Herzog, M. H.; Gerstner, W.

10.1101/2022.07.05.498835 — neuroscience — Posted on 2023-06-07

3483 Finding and exploring reproducible cell phenotypes with the Stemformatics data portal

Choi, J.; Butcher, S.; Angel, P.; Bransfield, J.; Barry, J.; Faux, N.; Shaban, B.; Pillai, P.; Michalewicz, A.; Wells, C. A.

10.1101/2023.06.05.543705 — systems biology — Posted on 2023-06-07

3484 In silico characterization of five novel disease-resistance proteins in Oryza sativa sp. japonica against bacterial leaf blight and rice blast diseases

Dhiman, V.; Biswas, S.; Shekhawat, R. S.; Sadhukhan, A.; Yadav, P.

10.1101/2023.06.05.543715 — bioinformatics — Posted on 2023-06-07

3485 SparseRNAFolD: Sparse RNA pseudoknot-free Folding including Dangles

Gray, M.; Jabbari, H.; Will, S.

10.1101/2023.06.05.543808 — bioinformatics — Posted on 2023-06-07

3486 Ontogenetic Patterns in Juvenile Blue Crab density: Effects of Habitat and Turbidity in a Chesapeake Bay Tributary

Hyman, A.; Chiu, G.; Seebo, M.; Smith, A.; Saluta, G.; Lipcius, R.

10.1101/2023.06.05.543724 — ecology — Posted on 2023-06-07

3487 Environmental variability can promote parasite diversity within hosts and transmission among hosts

Jarvis-Cross, M.; Krkosek, M.

10.1101/2023.06.05.543787 — ecology — Posted on 2023-06-07

3488 Alterations in type 2 dopamine receptors across neuropsychiatric conditions: A large-scale PET cohort

Malen, T.; Santavirta, S.; De Maeyer, S.; Tuisku, J.; Kaasinen, V.; Kankare, T.; Isojärvi, J.; Rinne, J.; Hietala, J.; Nuutila, P.; Nummenmaa, L.

10.1101/2023.06.05.543660 — neuroscience — Posted on 2023-06-07

3489 Imagination as predictive perception: mental imagery predictively biases perceptual judgments of observed action kinematics.

PARROTTA, E.; McDonough, K.; Bach, P.

10.1101/2023.06.07.544005 — neuroscience — Posted on 2023-06-07

3490 The relevance of accounting for parasympathetic as well as sympathetic arousal in threat conditioning: methodological and clinical considerations

Jaswetz, L.; de Voogd, L.; Becker, E. S.; Roelofs, K.

10.1101/2023.06.06.540498 — physiology — Posted on 2023-06-07

3491 Boldine alters serum lipidomic signatures after acute spinal cord transection in male mice

Graham, Z. A.; Siedlik, J. A.; Toro, C. A.; Harlow, L.; Cardozo, C. P.

10.1101/2023.06.05.543746 — physiology — Posted on 2023-06-07

3492 TaxaHFE: A machine learning approach to collapse microbiome datasets using taxonomic structure

Oliver, A.; Lemay, D. G.

10.1101/2023.06.06.543755 — bioinformatics — Posted on 2023-06-07

3493 Accelerating Cancer Vaccine Development for Human T-Lymphotropic Virus (HTLV) Using a High-Throughput Molecular Dynamics Approach

Moin, A. T.; Rani, N. A.; Ullah, M. A.; Patil, R. B.; Robin, T. B.; Nawal, N.; Zubair, T.; Mahamud, S. I.; Sakib, M. N.; Islam, N. N.; Khaleque, M. A.; Absar, N.; Shohael, A. M.

10.1101/2023.06.07.544070 — bioinformatics — Posted on 2023-06-07

3494 Electrocatalytic on-site oxygenation for transplanted cell-based-therapies

Lee, I.; Surendran, A.; Fleury, S.; Gimino, I.; Curtiss, A.; Fell, C.; Shiwarski, D.; El-Refy, O.; Rothrock, B.; Jo, S.; Schwartzkopff, T.; Singh Mehta, A.; John, S.; Ji, X.; Nikiforidis, G.; Hester, J.; Weber, D. J.; Veiseh, O.; Feinberg, A.; Rivnay, J.; Cohen-Karni, T.

10.1101/2023.06.05.543794 — bioengineering — Posted on 2023-06-07

3495 Tissue-bound hyaluronan molecular weight as a regulator of dendritic cell immune potency

Quartey, B. C.; Sapudom, J.; ElGindi, M.; Alatoom, A.; Teo, J.

10.1101/2023.06.06.543835 — bioengineering — Posted on 2023-06-07

3496 Modeling the Structure and DAP5 Binding Site of a Cap-Independent Translational Enhancer mRNA

Whittaker, A. M.; Goss, D. J.

10.1101/2023.06.07.542187 — biochemistry — Posted on 2023-06-07

3497 Bacteriophage diet breadth is impacted by interactions between bacteria

Bisesi, A. T.; Moebius, W.; Nadell, C. D.; Hansen, E. G.; Bowden, S. D.; Harcombe, W. R.

10.1101/2023.06.05.543762 — ecology — Posted on 2023-06-07

3498 Does improved (Limu) maize variety adoption improves rural households' food security: evidence from Dale Wabara district, Ethiopia.

Tesfa, B.; Eneyew, A.; Mitiku, F.

10.1101/2023.06.06.543866 — ecology — Posted on 2023-06-07

3499 Graded FGF activity patterns distinct cell types within the apical sensory organ of the sea anemone Nematostella vectensis

Sabin, K. Z.; Chen, S.; Hill, E. M.; Weaver, K. J.; Yonker, J.; Kirkman, M.; Redwine, B.; Klompen, A. M. L.; Zhao, X.; Guo, F.; McKinney, M. C.; Dewey, J. L.; Gibson, M. C.

10.1101/2023.06.07.544043 — developmental biology — Posted on 2023-06-07

3500 Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy

Sikder, K.; Phillips, E.; Zhong, Z.; Wang, N.; Saunders, J.; Mothy, D.; Kossenkov, A.; Schneider, T.; Nichtova, Z.; Csordas, G.; Margulies, K. B.; Choi, J. C.

10.1101/2023.02.14.528563 — cell biology — Posted on 2023-06-07

3501 Impaired cerebellar plasticity hypersensitizessensory reflexes in SCN2A-associated ASD

Wang, C.; Derderian, K. D.; Hamada, E.; Zhou, X.; Nelson, A. D.; Kyoung, H.; Ahituv, N.; Bouvier, G.; Bender, K.

10.1101/2023.06.05.543814 — neuroscience — Posted on 2023-06-07

3502 Dynamic functional connectivity in the right temporoparietal junction captures variations in autistic trait expression

Bravo Balsa, L.; Abu-Akel, A.; Mevorach, C.

10.1101/2023.06.05.543654 — neuroscience — Posted on 2023-06-07

3503 Marked irregular myofiber shape is a hallmark of human skeletal muscle aging and is reversed by heavy resistance training

Soendenbroe, C.; Karlsen, A.; Svensson, R. B.; Kjaer, M.; Andersen, J. L.; Mackey, A. L.

10.1101/2023.06.05.543651 — physiology — Posted on 2023-06-07

3504 Intraspecific genetic variation is critical to robust toxicological predictions in Daphnia

Shahmohamadloo, R. S.; Rudman, S. M.; Clare, C. I.; Westrick, J. A.; De Meester, L.; Fryxell, J. M.

10.1101/2023.06.06.543817 — pharmacology and toxicology — Posted on 2023-06-07

3505 DanioCTC: Injection of circulating tumor cells from metastatic breast cancer patients in zebrafish xenografts for analysis of metastasis

Reinhardt, F.; Coen, L.; Rivandi, M.; Franken, A.; Sawitning Ayu Setyono, E.; Lindenberg, T.; Eberhardt, J.; Fehm, T.; Niederacher, D.; Knopf, F.; Neubauer, H.

10.1101/2023.06.05.543673 — cancer biology — Posted on 2023-06-07

3506 Dual mechanism of kinetochore microtubule detachment

Conway, W.; Ha, G.; Needleman, D. J.

10.1101/2023.06.05.543640 — biophysics — Posted on 2023-06-07

3507 Stability and Manoeuvrability Interactions During Human Walking Depend on the Manoeuvre Direction

Kulkarni, R. N.; Grover, F. M.; Shafer, A.; Schmitz, X.; Gordon, K. E.

10.1101/2023.06.06.543488 — bioengineering — Posted on 2023-06-07

3508 Deformable Cell-Like Microlasers for Real-Time Mechanical Quantification in Organoids

Fang, G.; Chen, Y.-C.

10.1101/2023.06.05.543717 — bioengineering — Posted on 2023-06-07

3509 Learning and memory in hybrid migratory songbirds - cognition as a reproductive isolating barrier across seasons

Alario, A.; Trevino, M.; Justen, H.; Woodman, C. J.; Roth, T. C.; Delmore, K. E.

10.1101/2023.06.07.544084 — animal behavior and cognition — Posted on 2023-06-07

3510 Aeroplane wing, a new recessive autosomal phenotypic marker in malaria vector, Anopheles stephensi Liston

Ghosh, C.; M, S.; Kumar, N.; Ramanjini, C. K.; Joshi, S. G.; S, S. K.; Subramani, S.; Swain, S.

10.1101/2023.06.05.543679 — genetics — Posted on 2023-06-07

3511 The nerodevelopmental genes alan shepard and Neuroglian contribute to female mate preference in African Drosophila melanogaster

Roy, P. R.; Castillo, D. M.

10.1101/2022.05.15.491994 — evolutionary biology — Posted on 2023-06-07

3512 Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps

Colinet, D.; Cavigliasso, F.; Leobold, M.; Pichon, A.; Urbach, S.; Cazes, D.; Poullet, M.; Belghazi, M.; Volkoff, A.-N.; Drezen, J.-M.; Gatti, J.-L.; Poirie, M.

10.1101/2023.06.05.543686 — evolutionary biology — Posted on 2023-06-07

3513 MYC is essential for induction of major ZGA and subsequent preimplantation development

Yamamoto, T.; Wang, H.; Sato, H.; Honda, S.; Ikeda, S.; Minami, N.

10.1101/2023.06.06.543968 — developmental biology — Posted on 2023-06-07

3514 Accurate staging of chick embryonic tissues via deep learning

Groves, I.; Holmshaw, J.; Furley, D.; Towers, M.; Evans, B. D.; Placzek, M.; Fletcher, A. G.

10.1101/2022.02.18.480991 — developmental biology — Posted on 2023-06-07

3515 Neural substrates of top-down processing during perceptual duration-based timing and beat-based timing

Niida, M.; Haruki, Y.; Imai, F.; Ogawa, K.

10.1101/2023.06.06.543032 — neuroscience — Posted on 2023-06-07

3516 Brain Templates for Chinese Babies from Newborn to Three Months of Age

Geng, X.; Chan, P. H.; Lam, H. S.; Chu, W. C.; Wong, P. C.

10.1101/2023.06.05.543553 — neuroscience — Posted on 2023-06-07

3517 The long term effects of uncoupling interventions as a therapy for dementia in humans

Holt, A. G.; Davies, A. M.

10.1101/2023.06.05.543670 — systems biology — Posted on 2023-06-07

3518 A novel, precise and high-throughput technology for viroid detection in cannabis (MFDetectTM)

Fernandez i Marti, A.; Parungao, M.; Hollin, J.; Selimotic, B.; Farrar, G.; Seyler, T.; Anand, A.; Ahmad, R.

10.1101/2023.06.05.543818 — plant biology — Posted on 2023-06-07

3519 LIMBARE: an Advanced Linear Mixed-effects Breakpoint Analysis with Robust Estimation Method with Applications to Longitudinal Ophthalmic Studies

Lee, T.; Schuman, J.; Ramos Cadena, M. d. l. A.; Zhang, Y.; Wollstein, G.; Hu, J.

10.1101/2023.01.27.525884 — bioinformatics — Posted on 2023-06-07

3520 Precision-engineered biomimetics: the human fallopian tube

Crawford, A. J.; Forjaz, A.; Bhorkar, I.; Roy, T.; Schell, D.; Queiroga, V.; Ren, K.; Kramer, D.; Bons, J.; Huang, W.; Russo, G. C.; Lee, M.-H.; Schilling, B.; Wu, P.-H.; Shih, I.-M.; Wang, T.-L.; Kiemen, A.; Wirtz, D.

10.1101/2023.06.06.543923 — bioengineering — Posted on 2023-06-07

3521 The human Y and inactive X chromosomes similarly modulate autosomal gene expression

San Roman, A. K.; Skaletsky, H.; Godfrey, A. K.; Bokil, N. V.; Teitz, L.; Singh, I.; Blanton, L. V.; Bellott, D. W.; Pyntikova, T.; Lange, J.; Koutseva, N.; Hughes, J. F.; Brown, L.; Phou, S.; Buscetta, A.; Kruszka, P.; Banks, N.; Dutra, A.; Pak, E.; Lasutschinkow, P. C.; Keen, C.; Davis, S. M.; Lin, A. E.; Tartaglia, N. R.; Samango-Sprouse, C.; Muenke, M.; Page, D. C.

10.1101/2023.06.05.543763 — genetics — Posted on 2023-06-07

3522 DNA damage primes hematopoietic stem cells for direct megakaryopoiesis

Garyn, C. M.; Bover, O.; Murray, J. W.; Jing, M.; Salas-Briceno, K.; Ross, S. R.; Snoeck, H.-W.

10.1101/2023.05.13.540665 — cell biology — Posted on 2023-06-07

3523 Theta phase precession at encoding predicts subsequent memory of sensory-driven vector fields, & occurs in memory-dependent fields at retrieval

Poulter, S.; de Cothi, W.; Barry, C.; Lever, C.

10.1101/2023.06.05.543704 — neuroscience — Posted on 2023-06-07

3524 Cell type-specific contributions to a persistent aggressive internal state in female Drosophila

Chiu, H.; Robie, A. A.; Branson, K. M.; Vippa, T.; Epstein, S.; Rubin, G. M.; Anderson, D. J.; Schretter, C. E.

10.1101/2023.06.07.543722 — neuroscience — Posted on 2023-06-07

3525 Trading acyls and swapping sugars: metabolic innovations in Solanum trichomes

Fiesel, P. D.; Kerwin, R. A.; Jones, A. D.; Last, R. L.

10.1101/2023.06.05.542877 — plant biology — Posted on 2023-06-07

3526 The PALB2 DNA binding domain is an intrinsically disordered recombinase.

Kyriukha, Y.; Watkins, M. B.; Redington, J. M.; Hopkins, J. B.; Dastvan, R.; Pozzi, N.; Korolev, S.

10.1101/2023.06.01.543259 — biophysics — Posted on 2023-06-07

3527 DiffSegR: An RNA-Seq data driven method for differential expression analysis using changepoint detection

Liehrmann, A.; Delannoy, E.; Castandet, B.; Rigaill, G.

10.1101/2023.06.05.543691 — bioinformatics — Posted on 2023-06-07

3528 Direct Intake Estimation and Longitudinal Tracking of Solid-food Consumption (DIETS) in Drosophila

Thakare, M. R.; Choudhary, P.; Sunke, S.; Pydah, B.; Yadav, R. S. P.; Agrawal, P.; Das, G.

10.1101/2023.06.07.543033 — animal behavior and cognition — Posted on 2023-06-07

3529 Spatially and temporally distinct patterns of expression for VPS10P domain receptors in human cerebral organoids

Febbraro, F.; Andersen, H. H. B.; Willnow, T. E.

10.1101/2023.06.07.543827 — developmental biology — Posted on 2023-06-07

3530 E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation

Sharma, V.; Sachan, N.; Sarkar, B.; Mutsuddi, M.; Mukherjee, A.

10.1101/2023.06.06.543920 — developmental biology — Posted on 2023-06-07

3531 Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis.

Chengrui, A.; Farley, A. M.; Palmer, S.; Liu, D.; Kousa, A. I.; Rouse, P.; Major, V.; Sweetman, J.; Morys, J.; Corsinotti, A.; Nichols, J.; Ure, J.; McLay, R.; Boulter, L.; Chapman, J. S.; Tomlinson, S. R.; Blackburn, C. C.

10.1101/2023.06.07.544040 — developmental biology — Posted on 2023-06-07

3532 A Spatiotemporal Compartmentalization of Glucose Metabolism Guides Mammalian Gastrulation Progression

Cao, D.; Zhong, L.; Hemalatha, A.; Bergmann, J.; Cox, A. L.; Greco, V.; Sozen, B.

10.1101/2023.06.06.543780 — developmental biology — Posted on 2023-06-07

3533 Autism- and epilepsy-associated EEF1A2 mutations lead to translational dysfunction and altered acting bundling

Mohamed, M. S.; Klann, E.

10.1101/2023.06.06.543912 — neuroscience — Posted on 2023-06-07

3534 Recurrent pattern completion drives the neocortical representation of sensory inference

Shin, H.; Ogando, M. B.; Abdeladim, L.; Durand, S.; Belski, H.; Cabasco, H.; Loefler, H.; Bawany, A.; Hardcastle, B.; Wilkes, J.; Nguyen, K.; Suarez, L.; Johnson, T.; Han, W.; Ouellette, B.; Grasso, C.; Swapp, J.; Ha, V.; Young, A.; Caldejon, S.; Williford, A.; Groblewski, P.; Olsen, S.; Kiselycznyk, C.; Lecoq, J.; Adesnik, H.

10.1101/2023.06.05.543698 — neuroscience — Posted on 2023-06-07

3535 OptEnvelope: a target point guided method for growth-coupled production using knockouts

Motamedian, E.; Berzins, K.; Muiznieks, R.; Stalidzans, E.

10.1101/2023.03.10.532079 — systems biology — Posted on 2023-06-07

3536 Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish

Massoz, L.; Bergemann, D.; Lavergne, A.; Reynders, C.; Desiront, C.; Goossens, C.; Flasse, L.; Peers, B.; Voz, M.; Manfroid, I.

10.1101/2023.06.05.543680 — developmental biology — Posted on 2023-06-07

3537 Metabolomic analysis of Drosophila melanogaster larvae lacking Pyruvate kinase

Tennessen, J. M.; Heidarian, Y.; Tourigny, J. P.; Fasteen, T. D.; Mahmoudzadeh, N. H.; Hurlburt, A. J.; Nemkov, T.; Reisz, J. A.; D'Alessandro, A.

10.1101/2023.06.05.543743 — developmental biology — Posted on 2023-06-07

3538 Mannose is crucial for mesoderm specification and symmetry breaking in gastruloids

dingare, c.; Yang, J.; Steventon, B.

10.1101/2023.06.05.543730 — developmental biology — Posted on 2023-06-07

3539 Lineage motifs: developmental modules for control of cell type proportions

Tran, M.; Askary, A.; Elowitz, M.

10.1101/2023.06.06.543925 — developmental biology — Posted on 2023-06-07

3540 Effects of psychogenic stress on oxidative stress and antioxidant capacity at different growth stages.

LEE, S.; Itagaki, A.; Satoh, A.; Sugimoto, I.; Saito, T.; Tatehana, H.

10.1101/2023.06.07.544073 — developmental biology — Posted on 2023-06-07

3541 High-throughput mRNA-seq atlas of human placenta shows vast transcriptome remodeling from first to third trimester

Gonzalez, T. L.; Wertheimer, S.; Flowers, A. E.; Wang, Y.; Santiskulvong, C.; Clark, E. L.; Jefferies, C. A.; Lawrenson, K.; Chan, J. L.; Joshi, N. V.; Zhu, Y.; Tseng, H.-R.; Karumanchi, S. A.; Williams, J.; Pisarska, M. D.

10.1101/2023.06.06.543972 — developmental biology — Posted on 2023-06-07

3542 The Emergence of Circadian Timekeeping in the Intestine

Parasram, K.; Zuccato, A.; Shin, M.; Willms, R.; Deveale, B.; Foley, E.; Karpowicz, P.

10.1101/2023.06.06.543952 — developmental biology — Posted on 2023-06-07

3543 Post-acute immunological and behavioral sequelae in mice after Omicron infection

Ma, T.; Suryawanshi, R. K.; Miller, S. R.; Ly, K. K.; Thomas, R.; Elphick, N.; Yin, K.; Luo, X.; Kaliss, N.; Chen, I. P.; Montano, M.; Sreekumar, B.; Standker, L.; Munch, J.; Damron, F. H.; Palop, J. J.; Ott, M.; Roan, N. R.

10.1101/2023.06.05.543758 — microbiology — Posted on 2023-06-07

3544 Single cell RNA-seq analysis of spinal locomotor circuitry in larval zebrafish

Kelly, J. J.; Wen, H.; Brehm, P.

10.1101/2023.06.06.543939 — neuroscience — Posted on 2023-06-07

3545 PAX8 expressing epithelial cells are a cancer-prone source of clonal cyclical regeneration of endometrial epithelium

Fu, D.-J.; De Micheli, A. J.; Bidarimath, M.; Ellenson, L.; Cosgrove, B. D.; Flesken-Nikitin, A.; Nikitin, A.

10.1101/853994 — cancer biology — Posted on 2023-06-07

3546 The effects of inversion polymorphisms on patterns of neutral genetic diversity

Charlesworth, B.

10.1101/2023.02.23.529778 — genetics — Posted on 2023-06-07

3547 Phylogenetic comparative approach reveals evolutionary conservatism, ancestral composition, and integration of vertebrate gut microbiota

Perez-Lamarque, B.; Sommeria-Klein, G.; Duret, L.; Morlon, H.

10.1101/2023.01.03.522549 — evolutionary biology — Posted on 2023-06-07

3548 The molecular clock in long-lived tropical trees is independent of growth rate

Satake, A.; Imai, R.; Fujino, T.; Tomimoto, S.; Ohta, K.; Na'iem, M.; Indrioko, S.; Widiyatno, ; Purnomo, S.; Morales, A. M.; Nizhynska, V.; Tani, N.; Suyama, Y.; Sasaki, E.; Kasahara, M.

10.1101/2023.01.26.525665 — evolutionary biology — Posted on 2023-06-07

3549 Ocean-scale variation in migration schedules of a long-distance migratory seabird is fully compensated upon return to the breeding site

van Bemmelen, R. S. A.; Moe, B.; Schekkerman, H.; Hansen, S. A.; Snell, K. R. S.; Humphreys, E. M.; Mantyla, E.; Hallgrimsson, G. T.; Gilg, O.; Ehrich, D.; Calladine, J.; Hammer, S.; Harris, S. J.; Lang, J.; Vignisson, S. R.; Kolbeinsson, Y.; Nuotio, K.; Sillanpaa, M.; Sittler, B.; Sokolov, A.; Klaassen, R. H. G.; Phillips, R. A.; Tulp, I.

10.1101/2023.05.27.542544 — ecology — Posted on 2023-06-07

3550 High intraspecific growth variability despite strong evolutionary heritage in a neotropical forest

Schmitt, S.; Herault, B.; Derroire, G.

10.1101/2022.07.27.501745 — ecology — Posted on 2023-06-07

3551 The challenges of independence: ontogeny of at-sea behaviour in a long-lived seabird

Delord, K.; Weimerskirch, H.; Barbraud, C.

10.1101/2021.10.23.465439 — ecology — Posted on 2023-06-07

3552 Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells

Stathatos, G. G.; Merriner, D. J.; O'Connor, A. E.; Zenker, J.; Dunleavy, J. E.; O'Bryan, M. K.

10.1101/2023.06.07.544006 — developmental biology — Posted on 2023-06-07

3553 Structural Organization of the Retriever-CCC Endosomal Recycling Complex

Boesch, D. J.; Singla, A.; Han, Y.; Kramer, D. A.; Liu, Q.; Suzuki, K.; Juneja, P.; Zhao, X.; Long, X.; Medlyn, M. J.; Billadeau, D. D.; Chen, Z.; Chen, B.; Burstein, E.

10.1101/2023.06.06.543888 — cell biology — Posted on 2023-06-07

3554 Defining Microbial Community Functions in Chronic Human Infection with Metatranscriptomics

Adekoya, A. E.; Kargbo, H. A.; Ibberson, C.

10.1101/2023.06.06.543868 — microbiology — Posted on 2023-06-07

3555 The Caulobacter NtrB-NtrC two-component system bridges nitrogen assimilation and cell development

North, H.; McLaughlin, M.; Fiebig, A.; Crosson, S.

10.1101/2023.06.06.543975 — microbiology — Posted on 2023-06-07

3556 Genomic regions of durum wheat involved in water productivity.

Zaim, M.; Kehel, Z.; Garcia, M. S.; Belkadi, B.; Maltouf, A. F.; Al Abdallat, A.; Bassi, F. M.

10.1101/2023.06.07.544022 — plant biology — Posted on 2023-06-07

3557 Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease

Adero, M.; Tripathi, J.; Odour, R.; Zipfel, C.; Tripathi, L.

10.1101/2023.06.06.543870 — plant biology — Posted on 2023-06-07

3558 Natural genetic variation underlying the negative effect of elevated CO2 on ionome composition in Arabidopsis thaliana

Cassan, O.; Pimpare, L.-L.; Timothy, M.; Fizames, C.; Devidal, S.; Roux, F.; Milcu, A.; Lebre, S.; Gojon, A.; Martin, A.

10.1101/2023.06.05.543678 — plant biology — Posted on 2023-06-07

3559 FloraTraiter: Automated parsing of traits from descriptive biodiversity literature

Folk, R. A.; Guralnick, R. P.; LaFrance, R. T.

10.1101/2023.06.06.543883 — plant biology — Posted on 2023-06-07

3560 A novel, precise and high-throughput technology for viroid detection in cannabis (MFDetectTM)

Fernandez i Marti, A.; Parungao, M.; Selimotic, B.; Farrar, G.; Seyler, T.; Anand, A.; Ahmad, R.

10.1101/2023.06.05.543818 — plant biology — Posted on 2023-06-07

3561 Characterization of GAPDH expression related to biotic stress responses in Physcomitrella

Miniera, A. A.; Hoernstein, S. N. W.; van Gessel, N.; Peeters, J. O.; Reski, R.

10.1101/2023.06.07.544018 — plant biology — Posted on 2023-06-07

3562 Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex

Deng, S.; Cai, J.; Harrison, S.; Zhou, H.; Hinshaw, S. M.

10.1101/2023.06.06.543957 — cell biology — Posted on 2023-06-07

3563 The proprotein convertase BLI-4 promotes collagen secretion during assembly of the Caenorhabditis elegans cuticle

Birnbaum, S. K.; Cohen, J. D.; Belfi, A.; Murray, J. I.; Adams, J. R. G.; Chisholm, A. D.; Sundaram, M. V.

10.1101/2023.06.06.542650 — cell biology — Posted on 2023-06-07

3564 Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death by Activating a TGFbeta3/TFEB/STAT3 Pathway Early during Mammary Gland Involution

JEONG, J.; Lee, J.; Talaia, G.; Kim, W.; Song, J.; Hong, J.; Yoo, K.; Gonzalez, D.; Athonvarangkul, D.; Shin, J.; Dann, P.; Haberman, A.; Kim, L. K.; Ferguson, S.; Choi, J.; Wysolmerski, J.

10.1101/2022.05.17.492309 — cell biology — Posted on 2023-06-07

3565 Disentangling plant- and environment-mediated drivers of active rhizosphere bacterial community dynamics during short-term drought

Bandopadhyay, S.; Li, X.; Bowsher, A. W.; Last, R. L.; Shade, A.

10.1101/2023.06.06.543716 — microbiology — Posted on 2023-06-07

3566 CRISPR-Cas12a-Based Rapid and Sensitive Detection of rpoBL378R in Mycobacterium tuberculosis

Yang, Y. h.; Yang, L.; Li, X. y.; Tang, J.; Zhu, Y.; Ma, K.; Yang, Y. m.; Hui, Z. y.; Qin, Y. y.; Lei, H. t.; Shan, M. h.

10.1101/2023.06.06.543922 — microbiology — Posted on 2023-06-07

3567 Loss of OsARF18 confers glufosinate ammonium herbicide resistance in rice

Xia, J.-Q.; He, D.-Y.; Zhao, P.-X.; Xiang, C.

10.1101/2023.06.05.543806 — plant biology — Posted on 2023-06-07

3568 Genetic factors explaining anthocyanin pigmentation differences

Marin, M. F.; Pucker, B.

10.1101/2023.06.05.543820 — plant biology — Posted on 2023-06-07

3569 Replacing continuous stimulation of one set of electrodes with successive stimulation of multiple sets of electrodes can improve the focality of transcranial temporal interference stimulation (tTIS), especially the focality of stimulation towards deep brain regions: A simulation study.

Li, Y.; Zhang, W.

10.1101/2022.12.30.522357 — bioengineering — Posted on 2023-06-07

3570 Reversible translocation of acyl-CoA:cholesterol acyltransferase (ACAT) between the endoplasmic reticulum and vesicular structures

Schiffmann, A.; Ahlswede, L.; Gimpl, G.

10.1101/2023.06.06.543826 — cell biology — Posted on 2023-06-07

3571 Catalytic growth in a shared enzyme pool ensures robust control of centrosome size

Banerjee, D. S.; Banerjee, S.

10.1101/2023.06.06.543875 — cell biology — Posted on 2023-06-07

3572 Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

Neininger-Castro, A. C.; Hayes, J. B.; Sanchez, Z. C.; Taneja, N.; Fenix, A. M.; Moparthi, S.; Vassilopoulos, S.; Burnette, D. T.

10.1101/2023.01.11.523681 — cell biology — Posted on 2023-06-07

3573 Multiscale modeling of HBV infection integrating intra- and intercellular viral propagation for analyzing extracellular viral markers

Kitagawa, K.; Kim, K.; Iwamoto, M.; Hayashi, S.; Park, H.; Nishiyama, T.; Nakamura, N.; Fujita, Y.; Nakaoka, S.; Aihara, K.; Perelson, A. S.; Allweiss, L.; Dandri, M.; Watashi, K.; Tanaka, Y.; Iwami, S.

10.1101/2023.06.06.543822 — microbiology — Posted on 2023-06-07

3574 The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection

Lambert, C.; Bachmann, C.; Gaillard, M.; Hautcoeur, A.; Gloux, K.; Guilbert, T.; Mechats, C.; Prost, B.; Solgadi, A.; Abreu, S.; Andrieu, M.; Poyart, C.; Gruss, A.; FOUET, A.

10.1101/2023.06.07.543851 — microbiology — Posted on 2023-06-07

3575 Defining Microbial Community Functions in Chronic Human Infection with Metatranscriptomics

Adekoya, A. E.; Kargbo, H. A.; Ibberson, C.

10.1101/2023.06.06.543868 — microbiology — Posted on 2023-06-07

3576 FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD

Fujino, Y.; Ueyama, M.; Ishiguro, T.; Ozawa, D.; Ito, H.; Sugiki, T.; Murata, A.; Ishiguro, A.; Gendron, T.; Mori, K.; Tokuda, E.; Taminato, T.; Konno, T.; Koyama, A.; Kawabe, Y.; Takeuchi, T.; Furukawa, Y.; Fujiwara, T.; Ikeda, M.; Mizuno, T.; Mochizuki, H.; Mizusawa, H.; Wada, K.; Ishikawa, K.; Onodera, O.; Nakatani, K.; Petrucelli, L.; Taguchi, H.; Nagai, Y.

10.1101/2022.11.01.514717 — neuroscience — Posted on 2023-06-07

3577 Importin α as a molecular marker for investigating the microenvironment of micronuclei

Miyamoto, Y.; Kisanuki, R.; Oshima, R.; Hata, C.; Tachibana, T.; Oka, M.; Saitoh, H.

10.1101/2023.06.06.543979 — cell biology — Posted on 2023-06-07

3578 GLUT4 dynamic subcellular localization is controlled by AMP kinase activation as revealed by proximal proteome mapping in human muscle cells

Ray, A.; Wen, J.; Yammine, L.; Culver, J.; Garren, J.; Xue, L.; Hales, K.; Xiang, Q.; Birnbaum, M. J.; Zhang, B. B.; Monetti, M.; McGraw, T. E.

10.1101/2023.06.06.543897 — cell biology — Posted on 2023-06-07

3579 The white-footed deermouse, an infection tolerant reservoir for several zoonotic agents, tempers interferon responses to endotoxin in comparison to the mouse and rat

Milovic, A.; Duong, J. V.; Barbour, A. G.

10.1101/2023.06.06.543964 — microbiology — Posted on 2023-06-07

3580 The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

Dong, H.; He, K.; Yang, J.; Zheng, W.-B.; Lai, D.-H.; Liu, J.; Ding, H.-Y.; Wu, R.-B.; Brown, K. M.; Hide, G.; Lun, Z.-R.; Zhu, X.-Q.; Long, S.

10.1101/2023.06.06.543661 — microbiology — Posted on 2023-06-07

3581 The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics

Misare, K. R.; Ampolini, E. A.; Gonzalez, H. C.; Sullivan, K. A.; Li, X.; Miller, C.; Sosseh, B.; Dunne, J. B.; Voelkel-Johnson, C.; Gordon, K. L.; Hartman, J. H.

10.1101/2023.06.06.543785 — cell biology — Posted on 2023-06-07

3582 Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development

Shafaattalab, S.; LI, A. Y.; Maaref, Y.; Jayousi, F.; Hamledari, H.; Baygi, D. H.; Barszczewski, T.; Gunawan, M.; Rupai, B.; Jannati, S.; Nagalingam, R.; Cool, A. M.; Langa, P.; Solaro, R. J.; Sanatani, S.; Toepfer, C.; Lindert, S.; Lange, P. F.; Tibbits, G. F.

10.1101/2023.06.06.542948 — cell biology — Posted on 2023-06-07

3583 Motile bacteria leverage bioconvection for eco-physiological benefits in a natural aquatic environment

Di Nezio, F.; Roman, S.; Buetti-Dinh, A.; Sepulveda Steiner, O.; Bouffard, D.; Sengupta, A.; Storelli, N.

10.1101/2023.06.06.543831 — microbiology — Posted on 2023-06-07

3584 The microbial derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota

Kisthardt, S. C.; Thanissery, R.; Pike, C. M.; Foley, M. H.; Theriot, C. M.

10.1101/2023.06.06.543867 — microbiology — Posted on 2023-06-07

3585 MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting

Zeka, K.; Taylor, A. V.; Samarista, R.; Ragusa, D.; Suen, C.-W.; Cyran, O. W.; Domingues, A. F.; Meduri, E.; Huntly, B. J.; Forte, D.; Curti, A.; Pina, C.

10.1101/2023.06.05.543499 — cancer biology — Posted on 2023-06-07

3586 NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis

Wierczeiko, A.; Pastore, S.; Muendnich, S.; Busch, A. M.; Dietrich, V.; Helm, M.; Butto, T.; Gerber, S.

10.1101/2022.12.13.520220 — bioinformatics — Posted on 2023-06-07

3587 Evaluation of haplotype-aware long-read error correction with hifieval

Guo, Y.; Feng, X.; Li, H.

10.1101/2023.06.05.543788 — bioinformatics — Posted on 2023-06-07

3588 Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5

Hehl, L. A.; Horn-Ghetko, D.; Prabu, J. R.; Vollrath, R.; Vu, D. T.; Perez Berrocal, D. A.; Mulder, M. P. C.; van der Heden van Noort, G. J.; Schulman, B. A.

10.1101/2023.06.06.543850 — biochemistry — Posted on 2023-06-07

3589 Structural insights into the initiation of free radical formation in the Class Ib ribonucleotide reductases

Yadav, L. R.; Mande, S. C.

10.1101/2023.06.06.543845 — biochemistry — Posted on 2023-06-07

3590 Structural Basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB

Kot, E. F.; Goncharuk, S. A.; Franco, M. L.; Arseniev, A. S.; Benito-Martinez, A.; Costa, M.; Cattaneo, A.; Vilar, M.; Mineev, K. S.

10.1101/2023.06.06.543881 — biochemistry — Posted on 2023-06-07

3591 In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair

Baral, J.; Bhattacharje, G.; Dash, S.; Samanta, D.; Hinde, E.; Rouiller, I.; Das, A. K.

10.1101/2023.06.07.543977 — biochemistry — Posted on 2023-06-07

3592 The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with chemokine CXCL12

Mantonico, M. V.; De Leo, F.; Quilici, G.; Colley, L.; De Marchis, F.; Crippa, M.; Schulte, T.; Zucchelli, C.; Ricagno, S.; Giachin, G.; ghitti, m.; Bianchi, M. E.; Musco, G.

10.1101/2023.06.06.543836 — biochemistry — Posted on 2023-06-07

3593 Crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion

Gurusaran, M.; Erlandsen, B. S.; Davies, O. R.

10.1101/2023.06.05.543797 — biochemistry — Posted on 2023-06-07

3594 Linking intrinsic scales of ecological processes to characteristic scales of biodiversity and functioning patterns

Zelnik, Y. R.; Barbier, M.; Shanafelt, D. W.; Loreau, M.; Germain, R. M.

10.1101/2021.10.11.463913 — ecology — Posted on 2023-06-07

3595 Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population

Birzu, G.; Subrahmaniam Muralidharan, H.; Goudeau, D.; Malmstrom, R.; Fisher, D. S.; Bhaya, D.

10.1101/2023.06.06.543983 — microbiology — Posted on 2023-06-07

3596 Atypical Chemokine Receptor 1 (Ackr1)-deficient Mice Resist Lethal SARS-CoV-2 Challenge

Majumdar, S.; Weaver, J. D.; Pontejo, S. M.; Minai, M.; Georgia-Clark, S.; Gao, J.-L.; Lu, X.; Zhang, H.; Lackemeyer, N.; Burdette, T.; Johnson, R.; Kelsall, B. L.; Farber, J. M.; Alves, D. A.; Murphy, P. M.

10.1101/2023.06.05.543759 — immunology — Posted on 2023-06-07

3597 Neural, physiological and behavioral correlates of empathy for pain in Tourette syndrome

Weiblen, R.; Robert, C.; Petereit, P.; Heldmann, M.; Munte, T. F.; Munchau, A.; Muller-Vahl, K.; Kramer, U. M.

10.1101/2022.12.19.521056 — neuroscience — Posted on 2023-06-07

3598 Effects of growth feedback on gene circuits: A dynamical understanding

Kong, L.-W.; Shi, W.; Tian, X.; Lai, Y.-C.

10.1101/2023.06.06.543915 — synthetic biology — Posted on 2023-06-07

3599 Data-driven recombination detection in viral genomes

Alfonsi, T.; Bernasconi, A.; Chiara, M.; Ceri, S.

10.1101/2023.06.05.543733 — bioinformatics — Posted on 2023-06-07

3600 Identification of Therapeutic Leads from Ficus hispida Fruit Phytochemicals against Prostate Cancer Using Pharmacoinformatic and Molecular Dynamics Simulation Approach

Rahman, M. H.; Rahman, M. A.; Zahan, M. S.; Biswas, P.; Islam, S.; Reshad, R. A. I.; Sohag, A. A. M.; Gupta, B.; Islam, R.; Hannan, M. A.; Kim, W.; Moon, S.; Uddin, M. J.; Kim, B.

10.1101/2023.06.04.543596 — bioinformatics — Posted on 2023-06-07

3601 Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus

Brezellec, P.

10.1101/2023.06.06.543855 — genomics — Posted on 2023-06-07

3602 Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity

Yuan, M.; Feng, Z.; Lv, H.; So, N.; Shen, I. R.; Tan, T. J. C.; Teo, Q. W.; Ouyang, W. O.; Talmage, L.; Wilson, I. A.; Wu, N. C.

10.1101/2023.06.06.543969 — immunology — Posted on 2023-06-07

3603 Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies

Lu, X.; Hayashi, H.; Ishikawa, E.; Takeuchi, Y.; Dychiao, J. V. T.; Nakagami, H.; Yamasaki, S.

10.1101/2023.06.06.543529 — immunology — Posted on 2023-06-07

3604 Evolutionary conservation of the structure and function of meiotic Rec114-Mei4 and Mer2 complexes

Daccache, D.; De Jonge, E.; Liloku, P.; Mechleb, K.; Haddad, M.; Corthaut, S.; Sterckx, Y. G. J.; Volkov, A. N.; Claeys Bouuaert, C.

10.1101/2022.12.16.520760 — molecular biology — Posted on 2023-06-06

3605 The distinct translational landscapes of Gram-positive and Gram-negative bacteria

Bryant, O. J.; Lastovka, F.; Powell, J.; Chung, B. Y.

10.1101/2023.05.25.542305 — microbiology — Posted on 2023-06-06

3606 Trazodone rescues dysregulated synaptic and mitochondrial nascent translatomes in prion neurodegeneration

Albert-Gasco, H.; Smith, H. L.; Alvarez-Castelao, B.; Swinden, D.; Halliday, M.; Janaki-Raman, S.; Butcher, A.; Mallucci, G. R.

10.1101/2023.06.05.543732 — neuroscience — Posted on 2023-06-07

3607 Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson's GBA-N370S mutation

Do, Q. B.; Ng, B.; Marquez-Gomez, R.; Beccano-Kelly, D.; Ibarra-Aizpurua, N.; Caiazza, M.-C.; Lang, C.; Baleriola, J.; Bengoa-Vergniory, N.; Wade-Martins, R.

10.1101/2023.03.01.530566 — neuroscience — Posted on 2023-06-07

3608 Modern human expansion from (southern?) Africa: Origin, non-African ancestry, and linearity

Cenac, Z.

10.1101/2022.07.31.500977 — evolutionary biology — Posted on 2023-06-07

3609 Comparative analysis of two Caenorhabditis elegans kinesins KLP-6 and UNC-104 reveals common and distinct activation mechanisms in kinesin-3

Kita, T.; Chiba, K.; Wang, J.; Nakagawa, A.; Niwa, S.

10.1101/2023.04.18.537280 — cell biology — Posted on 2023-06-07

3610 Interleukin-21 Drives a Hypermetabolic State and CD4+ T Cell-associated Pathogenicity in Chronic Intestinal Inflammation

Bamidele, A. O.; Mishra, S. K.; Hirsova, P.; Fehrenbach, P. J.; Valenzuela-Perez, L.; Kim Lee, H. S.

10.1101/2023.06.02.543518 — immunology — Posted on 2023-06-06

3611 Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response

Deimel, L. P.; Xue, X.; Khan, A.; Moynie, L.; Buchanan, C. J.; Sun, G.; McBride, R.; Schuster, H.; Gauthier, C.; Saliba, R.; Leonavicius, K.; Minall, L.; Bort, G.; Russell, R. A.; Sezgin, E.; Paulson, J. C.; Anthony, D. C.; Baldwin, A. J.; Naismith, J.; Schiffner, T.; Davis, B. G.; Sattentau, Q. J.

10.1101/2023.06.03.543556 — immunology — Posted on 2023-06-06

3612 Conditional lethality profiling reveals anticancer mechanisms of action and drug-nutrient interactions

Flickinger, K. M.; Wilson, K. M.; Rossiter, N. J.; Hunger, A. L.; Lee, T. D.; Hall, M. D.; Cantor, J. R.

10.1101/2023.06.04.543621 — cancer biology — Posted on 2023-06-06

3613 Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis

10.1101/2023.05.31.542971 — bioengineering — Posted on 2023-06-06

3614 Analysis of Body-Fin Cooperative Propulsion Mechanism of Koi Carp Using Pose Estimation

Wu, X.; Wang, Y.; Wang, L.

10.1101/2022.09.07.507033 — animal behavior and cognition — Posted on 2023-06-07

3615 Near chromosome-level genome assembly of the microsporidium Hamiltosporidium tvaerminnensis

Angst, P.; Pombert, J.-F.; Ebert, D.; Fields, P. D.

10.1101/2023.06.02.543461 — genomics — Posted on 2023-06-07

3616 Yeast PRPP amidotransferase assembles into fine granules to promote de novo purine synthesis through intermolecular substrate channeling

Takaine, M.; Morita, R.

10.1101/2023.06.05.543815 — cell biology — Posted on 2023-06-07

3617 Monocyte production of C1q potentiates CD8+ T cell effector function following respiratory viral infection

Eddens, T.; Parks, O. B.; Lou, D.; Fan, L.; Sojati, J.; Ramsey, M. J.; Schmitt, L.; Salgado, C. M.; Reyes-Mugica, M.; Oury, T. D.; Byersdorfer, C.; Chen, K.; Williams, J. V.

10.1101/2023.06.04.543430 — immunology — Posted on 2023-06-06

3618 Sustained store-operated calcium entry utilizes activated chromatin state leads to instability in iTregs

Shi, Y.; Lv, H.; Yuan, G.; Liu, X.; Wang, X.; Geng, S.; Xia, T.; Zhou, X.; Li, Y.; Hu, X.

10.1101/2023.06.04.543629 — immunology — Posted on 2023-06-06

3619 lmeEEG: Mass linear mixed-effects modeling of EEG data with crossed random effects

Visalli, A.; Montefinese, M.; Viviani, G.; Finos, L.; Vallesi, A.; Ambrosini, E.

10.1101/2023.01.18.524560 — neuroscience — Posted on 2023-06-07

3620 Activation of the TRIF pathway and downstream targets results in the development of precancerous lesions during infection with Helicobacter.

Bali, P.; Lozano-Pope, I.; Hernandez, J.; Estrada, M. V.; Corr, M.; Turner, M. A.; Bouvet, M.; Benner, C.; Obonyo, M.

10.1101/2023.06.04.543598 — cancer biology — Posted on 2023-06-06

3621 CytoSIP: An annotated structural atlas for interactions involving cytokine or cytokine receptor

Wang, L.; Sun, F.; Ma, H.; Zhong, J.; Zhang, H.; Cheng, S.; Wu, H.; Wang, N.; Zhao, M.; Zhu, P.; Zheng, H.

10.1101/2023.06.05.543615 — immunology — Posted on 2023-06-06

3622 Cortical circuitry mediating inter-areal touch signal amplification

Ryan, L.; Sun-Yan, A.; Laughton, M.; Peron, S. P.

10.1101/2023.06.06.543886 — neuroscience — Posted on 2023-06-06

3623 Investigating miRNA signatures in metastatic breast cancer: An in silico analysis.

Harini, L.; Srivastava, S.; Ramesh, R.

10.1101/2023.06.04.543641 — cancer biology — Posted on 2023-06-06

3624 Prostate-derived circulating microRNAs add prognostic value to prostate cancer risk calculators

Zenner, M. L.; Kirkpatrick, B.; Leonardo, T. R.; Schlicht, M. J.; Saldana, A. C.; Loitz, C.; Valyi-Nagy, K.; Maienschein-Cline, M.; Gann, P. H.; Abern, M.; Nonn, L.

10.1101/2023.05.10.540236 — cancer biology — Posted on 2023-06-06

3625 What Strengthens Protein-Protein Interactions: Analysis and Applications of Residue Correlation Networks

Hung, T. I.; Hsieh, Y.-J.; Lu, W.-L.; Wu, K.-P.; Chang, C.-e.

10.1101/2023.03.15.532709 — biophysics — Posted on 2023-06-06

3626 Electrochemical biosensor based on NAD(P)H-dependent Quinone Reductase for rapid and efficient detection of vitamin K3

Khalife, M.; Stankovic, D.; Stankovic, V.; Danicka, J.; Rizzotto, F.; Costanche, V.; Slama-Schwok, A.; Gaudu, P.; Vidic, J.

10.1101/2023.06.02.543438 — biophysics — Posted on 2023-06-06

3627 Effects of sex and estrous cycle on intravenous oxycodone self-administration and the reinstatement of oxycodone-seeking behavior in rats

Hinds, N. M.; Wojtas, I. D.; Gallagher, C. A.; Corbett, C. M.; Manvich, D. F.

10.1101/2023.06.02.543393 — neuroscience — Posted on 2023-06-06

3628 Practice often and always get ready: a spiking mechanistic model for voluntary motor control

Zhao, C.; Cui, H.

10.1101/2023.06.02.543521 — neuroscience — Posted on 2023-06-06

3629 Shifts in carbon partitioning by photosynthetic activity increase terpenoid synthesis in glandulartrichomes

Saadat, N. P.; van Aalst, M.; Brand, A.; Ebenhoeh, O.; Tissier, A. F.; Matuszynska, A. B.

10.1101/2022.09.29.510054 — plant biology — Posted on 2023-06-06

3630 Investigating clot flow interactions by integrating intravital imaging with in silico modeling: flow, transport, and hemodynamic forces.

Teeraratkul, C.; Tomaiuolo, M.; Stalker, T. J.; Mukherjee, D.

10.1101/2023.06.03.543557 — biophysics — Posted on 2023-06-06

3631 Allosteric activation and inhibition of glycogen phosphorylase share common transient structural features

Kish, M.; Ivory, D. P.; Phillips, J. J.

10.1101/2023.06.03.543583 — biophysics — Posted on 2023-06-06

3632 Structural Insights on Ionizable Dlin-MC3-DMA Lipids in DOPC Layers by Combining Accurate Atomistic Force Fields, Molecular Dynamics Simulations and Neutron Reflectivity

Ibrahim, M.; Gilbert, J.; Heinz, M.; Nylander, T.; Schwierz, N.

10.1101/2023.02.28.529897 — biophysics — Posted on 2023-06-06

3633 Identification of a Non-Canonical Ciliate Nuclear Genetic Code Where UAA and UAG Code for Different Amino Acids

McGowan, J.; Kilias, E. S.; Alacid, E.; Lipscombe, J.; Jenkins, B. H.; Gharbi, K.; Kaithakottil, G. G.; Macaulay, I. C.; McTaggart, S.; Warring, S. D.; Richards, T. A.; Hall, N.; Swarbreck, D.

10.1101/2022.12.16.520718 — genomics — Posted on 2023-06-06

3634 Common evolutionary origins of the bacterial glycyl tRNA synthetase and alanyl tRNA synthetase

Alvarez-Carreno, C.; Arciniega, M.; Ribas de Pouplana, L.; Petrov, A. S.; Hernandez-Gonzalez, A.; Valencia-Sanchez, M. I.; Williams, L. D.; Torres-Larios, A.

10.1101/2023.05.29.542759 — evolutionary biology — Posted on 2023-06-06

3635 EBF1 limits the numbers of cochlear hair and supporting cells and forms the scala tympani and spiral limbus during inner ear development

Kagoshima, H.; Ohnishi, H.; Yamamoto, R.; Yasumoto, A.; Tona, Y.; Nakagawa, T.; Omori, K.; Yamamoto, N.

10.1101/2023.04.28.538789 — developmental biology — Posted on 2023-06-06

3636 Anti-NMDAR and non-anti-NMDAR antibodies promptly modulate NMDAR through p38 and flux-independent signaling: implications for anti-NMDAR encephalitis.

Montes de Oca Balderas, P.; Gomora-Garcia, J. C.; Massieu, L.; Hernandez-Cruz, A.

10.1101/2023.06.02.543471 — neuroscience — Posted on 2023-06-06

3637 Tactile Imagery Affects Cortical Responses to Vibrotactile Stimulation of the Fingertip

Morozova, M.; Yakovlev, L.; Syrov, N.; Perevoznyuk, G.; Lebedev, M.; Kaplan, A.

10.1101/2023.06.02.543456 — neuroscience — Posted on 2023-06-06

3638 Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

Dasgupta, A.; Hudspeth, A.

10.1101/2022.11.17.516962 — neuroscience — Posted on 2023-06-06

3639 Exploring the role of task success in implicit motor adaptation

Al-Fawakhiri, N.; Ma, A.; Taylor, J. A.; Kim, O. A.

10.1101/2023.02.01.526533 — neuroscience — Posted on 2023-06-06

3640 Removing the Gβγ-SNAP25 brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

Ceddia, R. P.; Zurawski, Z.; Thompson Gray, A.; Adegboye, F.; McDonald-Boyer, A.; Shi, F.; Liu, D.; Maldonado, J.; Feng, J.; Li, Y.; Alford, S.; Ayala, J. E.; McGuinness, O. P.; Collins, S.; Hamm, H. E.

10.1101/2020.04.29.069138 — physiology — Posted on 2023-06-06

3641 Processing macromolecular diffuse scattering data

Meisburger, S. P.; Ando, N.

10.1101/2023.06.04.543637 — biophysics — Posted on 2023-06-06

3642 Lectin-Seq: a method to profile lectin-microbe interactions in native communities

McPherson, R. L.; Isabella, C. R.; Walker, R. L.; Sergio, D.; Bae, S.; Gaca, T.; Raman, S.; Nguyen, L. T. T.; Wesener, D. A.; Halim, M.; Wuo, M. G.; Dugan, A.; Kerby, R.; Ghosh, S.; Rey, F. E.; Dhennezel, C.; Pishchany, G.; Lensch, V.; Vlamakis, H.; Alm, E. J.; Xavier, R. J.; Kiessling, L. L.

10.1101/2022.12.14.520458 — biochemistry — Posted on 2023-06-06

3643 Comparative Whole-Brain Mapping of Isoflurane and Ketamine-Activated Nuclei and Functional Networks

Wang, Y. W.; Hu, Y.; Qi, J. T.; Zhang, Z.; Luo, M. Q.

10.1101/2023.06.03.543576 — neuroscience — Posted on 2023-06-06

3644 A New Behavioral Paradigm for Frustrative Non-reward Reveals a Global Change in Brain Networks by Frustration

Naik, A. A.; Ma, X.; Munyeshyaka, M.; Leibenluft, E.; Li, Z.

10.1101/2023.02.28.530477 — neuroscience — Posted on 2023-06-06

3645 Bifurcation in space: Emergence of function modularity in the neocortex

Wang, X.-J.; Jiang, J.; Pereira-Obilinovic, U.

10.1101/2023.06.04.543639 — neuroscience — Posted on 2023-06-06

3646 sAMP-VGG16: Drude polarizable force-field assisted image-based deep neural network prediction model for short antimicrobial peptides

Pandey, P.; Srivastava, A.

10.1101/2023.06.04.543607 — biophysics — Posted on 2023-06-06

3647 Capture Efficiency Of Long-Adapter Single-Strand Oligonucleotide Probe Libraries

Chkaiban, L.; Tosi, L.; Parekkadan, B.

10.1101/2023.06.02.543477 — genomics — Posted on 2023-06-06

3648 Brain-wide neural recordings in mice navigating physical spaces enabled by a cranial exoskeleton

Hope, J. A.; Beckerle, T.; Cheng, P.-H.; Viavattine, Z.; Feldkamp, M.; Fausner, S.; Saxena, K.; Ko, E.; Hryb, I.; Carter, R. E.; Ebner, T.; Kodandaramaiah, S. B.

10.1101/2023.06.04.543578 — neuroscience — Posted on 2023-06-06

3649 FONDUE: Robust resolution-invariant denoising of MR Images using Nested UNets

Adame-Gonzalez, W.; Dadar, M.; Farivar-Mohseni, R.; Chakravarty, M.; Brzezinski-Rittner, A.

10.1101/2023.06.04.543602 — neuroscience — Posted on 2023-06-06

3650 Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution

Banayan, N. E.; Loughlin, B. J.; Singh, S.; Forouhar, F.; Lu, G.; Wong, K.-H.; Neky, M.; Hunt, H. S.; Bateman, L. B.; Tamez, A.; Handelman, S. K.; Price, W. N.; Hunt, J. F.

10.1101/2023.06.03.543563 — biophysics — Posted on 2023-06-06

3651 RNA-induced allosteric coupling drives viral capsid assembly in bacteriophage MS2

Hamilton, S.; Modi, T.; Sulc, P.; Ozkan, S. B.

10.1101/2023.06.05.543665 — biophysics — Posted on 2023-06-06

3652 Plant mutations: slaying beautiful hypotheses by surprising evidence

Schmitt, S.; Heuret, P.; Troispoux, V.; Beraud, M.; Cazal, J.; Chancerel, E.; Cravero, C.; Guichoux, E.; Lepais, O.; Loureiro, J.; Marande, W.; Martin-Ducup, O.; Vincent, G.; Chave, J.; Plomion, C.; Leroy, T.; Heuertz, M.; Tysklind, N.

10.1101/2023.06.05.543657 — genomics — Posted on 2023-06-06

3653 H3K4 methylation regulates development, DNA repair, and virulence in Mucorales

Osorio-Concepcion, M.; Lax, C.; Lorenzo-Gutierrez, D.; Canovas-Marquez, J. T.; Tahiri, G.; Navarro, E.; Binder, U.; Nicolas, F. E.; Garre, V.

10.1101/2023.06.05.543666 — genetics — Posted on 2023-06-06

3654 Comodulation reduces interindividual variability of circuit output

Schneider, A. C.; Itani, O.; Cronin, E.; Daur, N.; Bucher, D.; Nadim, F.

10.1101/2023.06.03.543573 — neuroscience — Posted on 2023-06-06

3655 Alpha-band frequency and temporal windows in perception: A review andmeta-analysis of 25 experiments

Samaha, J.; Romei, V.

10.1101/2023.06.03.543590 — neuroscience — Posted on 2023-06-06

3656 Narrow-window DIA: Ultra-fast quantitative analysis of comprehensive proteomes with high sequencing depth

Guzman, U. H.; Martinez del Val, A.; Ye, Z.; Damoc, E.; Arrey, T. N.; Pashkova, A.; Denisov, E.; Petzoldt, J.; Peterson, A. C.; Harking, F.; Ostergaard, O.; Stewart, H.; Xuan, Y.; Hermanson, D.; Hock, C.; Makarov, A. A.; Zabrouskov, V.; Olsen, J. V.

10.1101/2023.06.02.543374 — systems biology — Posted on 2023-06-06

3657 What fraction of cellular DNA turnover becomes cfDNA?

Sender, R.; Noor, E.; Milo, R.; Dor, Y.

10.1101/2023.06.03.543527 — systems biology — Posted on 2023-06-06

3658 Explaining Deep Neural Networks for the Prediction of Translation Rates

Ohler, U.; Korbel, F.; Eroshok, E.

10.1101/2023.06.02.543405 — bioinformatics — Posted on 2023-06-06

3659 Mendelian randomization analysis with pleiotropy-robust log-linear model for binary outcomes

Li, M.; Huang, T.; Jia, J.

10.1101/2023.06.03.543587 — bioinformatics — Posted on 2023-06-06

3660 Phylomitogenomics bolsters the high-level classification of Demospongiae (phylum Porifera)

Lavrov, D. V.; Diaz, C.; Maldonado, M.; Morrow, C.; Perez, T.; Pomponi, S. A.; Thucker, R. W.

10.1101/2023.06.04.543631 — evolutionary biology — Posted on 2023-06-06

3661 Getting More by Asking for Less: Linking Species Interactions to Species Co-Distributions in Metacommunities

Barbier, M.; Bunin, G.; Leibold, M. A.

10.1101/2023.06.04.543606 — ecology — Posted on 2023-06-06

3662 Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model

Yaghmaeian Salmani, B.; Lahti, L.; Gillberg, L.; Jacobsen, J. K.; Mantas, I.; Svenningsson, P.; Perlmann, T.

10.1101/2023.06.05.543445 — neuroscience — Posted on 2023-06-06

3663 Spatial Transcriptomics of Meningeal Inflammation Reveals Variable Penetrance of Inflammatory Gene Signatures into Adjacent Brain Parenchyma

Gadani, S.; Singh, S.; Kim, S.; Calabresi, P.; Smith, M.; Bhargava, P.

10.1101/2023.06.02.543421 — neuroscience — Posted on 2023-06-06

3664 New genomic techniques, old divides: stakeholder attitudes towards new biotechnology regulation in the EU and UK

Menary, J.; Fuller, S. S.

10.1101/2023.06.04.543624 — plant biology — Posted on 2023-06-06

3665 DesiRNA: structure-based design of RNA sequences with a Monte Carlo approach

Wirecki, T.; Lach, G.; Jaryani, F.; Badepally, N. G.; Moafinejad, N.; Klaudel, G.; Bujnicki, J. M.

10.1101/2023.06.04.543636 — bioinformatics — Posted on 2023-06-06

3666 Genome-wide association study of heat stress response in Bos taurus

Czech, B.; Wang, Y.; Szyda, J.

10.1101/2023.06.05.543663 — bioinformatics — Posted on 2023-06-06

3667 The Non-Mevalonate Pathway Requires a Delicate Balance of Intermediates to Maximize Terpene Production

Raghavan, I.; Wang, Z.

10.1101/2023.06.04.543646 — bioengineering — Posted on 2023-06-06

3668 Movement Recognition via Channel-Activation-Wise sEMG Attention

Zhang, J.; Matsuda, Y.; Fujimoto, M.; Suwa, H.; Yasumoto, K.

10.1101/2023.06.03.543591 — bioengineering — Posted on 2023-06-06

3669 Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex

Tu, Y.-C.; Chao, F.-Y.; Tsai, M.-F.

10.1101/2023.06.06.543936 — biochemistry — Posted on 2023-06-06

3670 A ticket to ride: genetic structure and kdr mutations in Aedes aegypti populations along a road crossing the Amazon Rainforest in Amapa State, Brazil

Souza, B. S.; Lima, L. F.; Galardo, A. K. R.; Corbel, V.; Lima, J. B. P.; Martins, A. J.

10.1101/2023.06.05.543667 — evolutionary biology — Posted on 2023-06-06

3671 Mapping of snail intermediate host habitat reveals variability in schistosome and nonschistosome trematode transmission in endemic settings

Angelo, T.; Starkloff, N. C.; Mahalila, M. P.; Charles, J.; Civitello, D. J.; Kinung'hi, S.

10.1101/2023.06.04.543635 — ecology — Posted on 2023-06-06

3672 Methoxsalen inhibited the acquisition of nicotine self-administration: attenuation by cotinine replacement in rats

Ding, Z.-M.; Neslund, E. M.; Sun, D.; Tan, X.

10.1101/2023.06.04.543614 — neuroscience — Posted on 2023-06-06

3673 The Entrainment of the Substantia Nigra During Temporal Lobe Seizures is Dependent on the Seizure Onset Pattern

Connolly, M.; Jiang, J.; Gutekunst, C.-A.; Gross, R. E.; Devergnas, A.

10.1101/2023.06.04.543608 — neuroscience — Posted on 2023-06-06

3674 Microbial Changes occurring during oronasal fistula wound healing

Goudy, S. L.; Bradley, H. L.; Gacasan, C. A.; Toma, A.; Naudin, C. R.; Wuest, W. M.; Tomov, M. L.; Serpooshan, V.; Coskun, A. F.; Jones, R. M.

10.1101/2023.06.02.543508 — pathology — Posted on 2023-06-06

3675 HistoMIL: a Python package for training Multiple Instance Learning models on histopathology slides

Pan, S.; Secrier, M.

10.1101/2023.06.02.543494 — pathology — Posted on 2023-06-06

3676 Computational characterization of the interactions between novel Boronic Acid derivatives with urokinase-type plasminogen activator (uPA) and their binding energy

Shah, M.; Rafiq, M.; Habib, U.; Paracha, R. Z.; Shabbir, M.

10.1101/2023.06.05.543664 — bioinformatics — Posted on 2023-06-06

3677 COMSE: Analysis of Single-Cell RNA-seq Data Using Community Detection Based Feature Selection

Luo, Q.; Chen, Y.; Lan, X.

10.1101/2023.06.03.543526 — bioinformatics — Posted on 2023-06-06

3678 Discovering the mechanics of artificial and real meat

St. Pierre, S. R.; Rajasekharan, D.; Darwin, E. C.; Linka, K.; Levenston, M. E.; Kuhl, E.

10.1101/2023.06.04.543638 — bioengineering — Posted on 2023-06-06

3679 Mimicry in motion: A grasshopper species that looks like, and moves like, a sympatric butterfly

Loeffler-Henry, K.; Kang, C.; Dawson, J. W.; Sherratt, T. N.

10.1101/2023.06.04.543626 — animal behavior and cognition — Posted on 2023-06-06

3680 Species and habitat specific changes in bird activity in an urban environment during Covid 19 lockdown

Sun, C.; Hassin, Y.; Boonman, A.; Shwartz, A.; Yovel, Y.

10.1101/2023.06.03.543542 — animal behavior and cognition — Posted on 2023-06-06

3681 Optogenetic Stimulation of the Locus Coeruleus Enhances Appetitive Extinction in Rats

Lui, S.; Brink, A. K.; Corbit, L. H.

10.1101/2023.06.02.543452 — animal behavior and cognition — Posted on 2023-06-06

3682 Communication between wolf and domestic dog revealed from experimental scent marking

Stepniak, K. M.; Diserens, T. A.; Szewczyk, M.; Myslajek, R. W.; Kuijper, D. P. J.

10.1101/2023.06.04.543479 — animal behavior and cognition — Posted on 2023-06-06

3683 Photosynthetic CO2 response characteristics in canopy of Larix principis-rupprechtii Mayr. tree and practicability of three Models

wu, c.; Ma, X.; Liu, Q.; Huang, X.

10.1101/2023.06.04.543630 — ecology — Posted on 2023-06-06

3684 Intraspecific variation of two duckweed species influences response to microcystin-LR exposure

Rzodkiewicz, L. D.; Turcotte, M.

10.1101/2023.06.04.543632 — ecology — Posted on 2023-06-06

3685 A neuromorphic model of active vision shows spatio-temporal encoding in lobula neurons can aid pattern recognition in bees

MaBouDi, H.; Roper, M.; Guiraud, M.-G.; Chittka, L.; Marshall, J. A. R.

10.1101/2023.06.04.543620 — neuroscience — Posted on 2023-06-06

3686 Exposure to temporal randomness promotes subsequent adaptation to new temporal regularities

Shdeour, O. R.; Tal-Perry, N.; Glickman, M.; Yuval-Greenberg, S.

10.1101/2023.06.04.543595 — neuroscience — Posted on 2023-06-06

3687 A class of secreted mammalian peptides with potential to expand cell-cell communication

Wiggenhorn, A. L.; Abuzaid, H. Z.; Coassolo, L.; Li, V. L.; Tanzo, J. T.; Wei, W.; Lyo, X.; Svensson, K. J.; Long, J. Z.

10.1101/2023.06.02.543503 — physiology — Posted on 2023-06-06

3688 Vasodilators activate TMEM16A channels in endothelial cells to reduce blood pressure

Mata-Daboin, A.; Garrud, T. A. C.; Fernandez-Pena, C.; Peixoto-Neves, D.; Leo, M. D.; Bernardelli, A.; Singh, P.; Malik, K. U.; Jaggar, J. H.

10.1101/2023.06.02.543450 — physiology — Posted on 2023-06-06

3689 Micro-circulating hyperdynamic blood flow as a key pathogenic factor in early sepsis

Feng, X.; Zeng, Y.; Sun, Y. B.; Yu, B.-W.

10.1101/2023.06.04.543593 — pathology — Posted on 2023-06-06

3690 A Boltzmann model predicts glycan structures from lectin binding

Yom, A.; CHIANG, W.-T.; Lewis, N.

10.1101/2023.06.03.543532 — bioinformatics — Posted on 2023-06-06

3691 Circulating Small Extracellular Vesicle RNA Profiling for the Detection of T1a stage Colorectal Cancer and Precancerous Advanced Adenoma

Min, L.; Bu, F.; Meng, J.; Liu, X.; Guo, Q.; Zhao, L.; Li, Z.; Li, X.; Zhu, S.; Zhang, S.

10.1101/2023.06.04.543604 — bioinformatics — Posted on 2023-06-06

3692 Oxygen loss compromises the survival and cognition of a coastal cephalopod

Court, M.; Macau, M.; Ranucci, M.; Lopes, V. M.; Repolho, T.; Paula, J. R.

10.1101/2023.06.03.543560 — animal behavior and cognition — Posted on 2023-06-06

3693 Clustering temporal step-counting patterns for 24 hours with machine learning revealed potential heterogeneity in the categorization by a traditional tertile procedure

Nawrin, S. S.; Inada, H.; Momma, H.; Nagatomi, R.

10.1101/2023.06.04.543652 — animal behavior and cognition — Posted on 2023-06-06

3694 The VR Billboard Paradigm: Using VR and Eye-tracking to Examine the Exposure-Reception-Retention Link in Realistic Communication Environments

Schmaelzle, R.; Lim, S.; Cho, H. J.; Wu, J.; Bente, G.

10.1101/2023.06.03.543559 — animal behavior and cognition — Posted on 2023-06-06

3695 A Quantitative Analysis of Locomotor Patterns in Developing C. elegans

Hassinan, C. W.; Sterrett, S. C.; Summy, B.; Khera, A.; Wang, A.; Bai, J.

10.1101/2023.06.03.543584 — animal behavior and cognition — Posted on 2023-06-06

3696 miniBUSCO: a faster and more accurate reimplementation of BUSCO

Huang, N.; Li, H.

10.1101/2023.06.03.543588 — genomics — Posted on 2023-06-06

3697 Recurrence and propagation of past functions through mineral facilitated horizontal gene transfer

Verma, T.; Hendiani, S.; Carbajo Moral, C. K.; Andersen, S. B.; Hammarlund, E.; Burmoelle, M.; Sand, K. K.

10.1101/2023.01.24.525235 — evolutionary biology — Posted on 2023-06-06

3698 Trazodone rescues dysregulated synaptic and mitochondrial nascent translatomes in neurodegeneration

Albert-Gasco, H.; Smith, H. L.; Alvarez-Castelao, B.; Swinden, D.; Halliday, M.; Janaki-Raman, S.; Butcher, A.; Mallucci, G. R.

10.1101/2023.06.05.543732 — neuroscience — Posted on 2023-06-06

3699 High-throughput confocal airy beam oblique light-sheet tomography of brain-wide imaging at single-cell resolution

Qi, X.; Castaneda, R. M.; Narasimhan, A.; Ding, L.; Chen, X.; Elowsky, C.; Palmer, J.; Drewes, R.; Sun, J.; Mizrachi, J.; Peng, H.; Wu, Z.; Osten, P.

10.1101/2023.06.04.543586 — neuroscience — Posted on 2023-06-06

3700 A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training

Roberts, M.; Ruple, B.; Godwin, J.; McIntosh, M.; Chen, S.-Y.; Kontos, N.; Agyin-Birikorang, A.; Michel, J. M.; Plotkin, D.; Mattingly, M.; Mobley, C. B.; Ziegenfuss, T.; Fruge, A.; Kavazis, A.

10.1101/2023.06.02.543459 — physiology — Posted on 2023-06-06

3701 CD38 assigns physiological function to soluble uric acid

Wen, S.; Arakawa, H.; Yokoyama, S.; Shirasaka, Y.; Higashida, H.; Tamai, I.

10.1101/2023.06.03.543541 — physiology — Posted on 2023-06-06

3702 Subcutaneous and orally self-administered high-dose carprofen in male and female mice: pharmacokinetics, tolerability and impact on cage-side pain indicators

Glasenapp, A.; Bankstahl, J. P.; Baehre, H.; Glage, S.; Bankstahl, M.

10.1101/2023.06.03.543582 — pharmacology and toxicology — Posted on 2023-06-06

3703 Benchmarking DIA data analysis workflows

Staes, A.; Maia, T. M.; Dufour, S.; Bouwmeester, R.; Gabriels, R.; Martens, L.; Impens, F.; Devos, S.

10.1101/2023.06.02.543441 — bioinformatics — Posted on 2023-06-06

3704 Rapid and sensitive detection of genome contamination at scale with FCS-GX

Astashyn, A.; Tvedte, E. S.; Sweeney, D.; Sapojnikov, V.; Bouk, N.; Joukov, V.; Mozes, E.; Strope, P. K.; Sylla, P. M.; Wagner, L.; Bidwell, S. L.; Clark, K.; Davis, E. W.; Smith-White, B.; Hlavina, W.; Pruitt, K. D.; Schneider, V. A.; Murphy, T. D.

10.1101/2023.06.02.543519 — bioinformatics — Posted on 2023-06-06

3705 A novel motoneuron-driven computational muscle model with motor unit resolution for subject-specific simulations of human voluntary muscle contraction

Caillet, A. H.; Phillips, A. T.; Farina, D.; Modenese, L.

10.1101/2023.06.03.543552 — bioengineering — Posted on 2023-06-06

3706 22kHz Ultrasonic Vocalizations and Body Freezing May Represent Two Systems of Fear in Rodent Fear Conditioning Paradigms

Zheng, B.; Bao, L.; Yu, D.; Yin, B.

10.1101/2023.06.02.543520 — animal behavior and cognition — Posted on 2023-06-06

3707 Near-chromosome level genome assembly of devil firefish, Pterois miles

Kitsoulis, C. V.; Papadogiannis, V.; Kristoffersen, J. B.; Kaitetzidou, E.; Sterioti, A.; Tsigenopoulos, C. S.; Manousaki, T.

10.1101/2023.01.10.523469 — genomics — Posted on 2023-06-06

3708 Conjunctive vector coding and place coding in hippocampus share a common directional signal

Zhou, Y.-Q.; Puliyadi, V.; Chen, X.; Lee, J. L.; Zhang, L.-Y.; Knierim, J. J.

10.1101/2023.06.02.543340 — neuroscience — Posted on 2023-06-06

3709 Loss of Grin2a Causes a Transient Delay in the Electrophysiological Maturation of Hippocampal Parvalbumin Interneurons

Camp, C. R.; Vlachos, A.; Klockner, C.; Krey, I.; Banke, T.; Shariatzadeh, N.; Ruggiero, S. M.; Galer, P.; Park, K. L.; Caccavano, A.; Kimmel, S.; Yuan, X.; Yuan, H.; Helbig, I.; Benke, T. A.; Lemke, J. R.; Pelkey, K. A.; McBain, C. J.; Traynelis, S. F.

10.1101/2021.12.29.474447 — neuroscience — Posted on 2023-06-06

3710 Lamivudine (3TC), a nucleoside reverse transcriptase inhibitor, prevents the neuropathological alterations present in mutant tau transgenic mice

Valles-Saiz, L.; Avila, J.; Hernandez, F.

10.1101/2023.06.02.543424 — neuroscience — Posted on 2023-06-06

3711 Necessary Role of Acute Ceramide Formation in The Human Microvascular Endothelium During Health and Disease

SenthilKumar, G.; Katunaric, B.; Zirgibel, Z.; Lindemer, B.; Jaramillo-Torres, M. J.; Bordas-Murphy, H.; Schulz, M. E.; Pearson, P. J.; Freed, J. K.

10.1101/2023.06.02.543341 — physiology — Posted on 2023-06-06

3712 Antibody Complementarity-Determining Region Sequence Design using AlphaFold2 and Binding Affinity Prediction Model

Ueki, T.; Ohue, M.

10.1101/2023.06.02.543382 — bioinformatics — Posted on 2023-06-06

3713 Reference genome choice and filtering thresholds jointly influence phylogenomic analyses

Rick, J. A.; Brock, C. D.; Lewanski, A. L.; Golcher-Benavides, J.; Wagner, C. E.

10.1101/2022.03.10.483737 — bioinformatics — Posted on 2023-06-06

3714 In silico simulations reveal molecular mechanism of uranyl ion toxicity towards DNA-binding domain of PARP-1 protein

Bulavko, E. S.; Ivankov, D. N.

10.1101/2023.06.02.543417 — bioinformatics — Posted on 2023-06-06

3715 Homodecameric Rad52 promotes single-position Rad51 nucleation in homologous recombination

Deveryshetty, J.; Chadda, R.; Mattice, J.; Karunakaran, S.; Rau, M.; Basore, K.; Pokhrel, N.; Englander, N.; Fitzpatrick, J.; Bothner, B.; Antony, E.

10.1101/2023.02.05.527205 — biochemistry — Posted on 2023-06-06

3716 Nociception in chicken embryos, Part III: Analysis of movements before and after application of a noxious stimulus

Suess, S. C.; Werner, J.; Saller, A. M.; Weiss, L.; Reiser, J.; Ondracek, J. M.; Zablotski, Y.; Kollmansperger, S.; Anders, M.; Schusser, B.; Fenzl, T.; Baumgartner, C.

10.1101/2023.04.20.537674 — animal behavior and cognition — Posted on 2023-06-06

3717 Multi-Scale Cortical Bone Traits Vary in Two Mouse Models of Genetic Diversity

Migotsky, N.; Kumar, S.; Shuster, J. T.; Coulombe, J. C.; Senwar, B.; Gestos, A. A.; Farber, C. R.; Ferguson, V. L.; Silva, M. J.

10.1101/2023.06.02.543484 — genomics — Posted on 2023-06-06

3718 Identification of domains in Plasmodium falciparum proteins of unknown function using DALI search on Alphafold predictions

Behrens, H. M.; Spielmann, T.

10.1101/2023.06.05.543710 — cell biology — Posted on 2023-06-06

3719 Amyloid β Induces Lipid Droplet-Mediated Microglial Dysfunction in Alzheimer's Disease

Prakash, P.; Manchanda, P.; Paouri, E.; Bisht, K.; Sharma, K.; Wijewardhane, P. R.; Randolph, C. E.; Clark, M. G.; Fine, J.; Thayer, E. A.; Crockett, A. M.; Gasmi, N.; Stanko, S.; Prayson, R.; Zhang, C.; Davalos, D.; Chopra, G.

10.1101/2023.06.04.543525 — neuroscience — Posted on 2023-06-06

3720 A neuronal least-action principle for real-time learning in cortical circuits

Senn, W.; Dold, D.; Kungl, A.; Ellenberger, B.; Jordan, J.; Bengio, Y.; Sacramento, J.; Petrovici, M. A.

10.1101/2023.03.25.534198 — neuroscience — Posted on 2023-06-06

3721 Quantitative Analysis of the Optogenetic Excitability of CA1 Neurons

Schoeters, R.; Tarnaud, T.; Weyn, L.; Joseph, W.; Raedt, R.; Tanghe, E.

10.1101/2023.06.02.543419 — neuroscience — Posted on 2023-06-06

3722 Transposable elements contribute to the establishment of the glycine shuttle in Brassicaceae species

Triesch, S.; Denton, A. K.; Bouvier, J.; Buchmann, J. P.; Reichel-Deland, V.; Martins Guerreiro, R. N. F.; Busch, N.; Schlueter, U.; Stich, B.; Kelly, S.; Weber, A. P. M.

10.1101/2022.12.06.519256 — plant biology — Posted on 2023-06-06

3723 High total water loss driven by low-fat diet in desert-adapted mice

Blumstein, D. M.; Colella, J. P.; Linder, E.; MacManes, M. D.

10.1101/2022.04.15.488461 — physiology — Posted on 2023-06-06

3724 Energy landscape steering mediates dynamic coupling in ATP-driven protein translocation by the bacterial Sec machinery

Crossley, J. A.; Allen, W. J.; Watkins, D. W.; Sabir, T.; Radford, S. E.; Tuma, R.; Collinson, I.; Fessl, T.

10.1101/793943 — biophysics — Posted on 2023-06-06

3725 Base Editor-Mediated Pooled Screening of Functional Mutations in Bacteria for Industrial Phenotypes

Yuan, Y.; Liao, X.; Li, S.; Xing, X.-h.; Zhang, C.

10.1101/2022.09.27.509808 — bioengineering — Posted on 2023-06-06

3726 Assessing the dynamics of Mycobacterium bovis infection in three French badger populations

Calenge, C.; Payne, A.; Reveillaud, E.; Richomme, C.; Girard, S.; Desvaux, S.

10.1101/2023.05.31.543041 — ecology — Posted on 2023-06-06

3727 Vision rivals audition in alerting humans for fast action

Dietze, N.; Poth, C. H. H.

10.1101/2023.06.02.543380 — neuroscience — Posted on 2023-06-06

3728 Melatonin suppression by light involves different retinal photoreceptors in young and older adults

Najjar, R. P.; Prayag, A. S.; Gronfier, C.

10.1101/2023.06.02.543372 — neuroscience — Posted on 2023-06-06

3729 Ultrasonographic measurements of fascicle length overestimate adaptations in serial sarcomere number

Hinks, A.; Franchi, M.; Power, G. A.

10.1101/2023.06.02.543410 — physiology — Posted on 2023-06-06

3730 Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation

Marin, E. C.; Morris, B. J.; Stuerner, T.; Champion, A. S.; Krzeminski, D.; Badalamente, G.; Gkantia, M.; Dunne, C. R.; Eichler, K.; Takemura, S.-y.; Tamimi, I. F. M.; Fang, S.; Moon, S. S.; Cheong, H. S. J.; Li, F.; Schlegel, P.; Berg, S.; FlyEM Project Team, ; Card, G. M.; Costa, M.; Shepherd, D.; Jefferis, G. S. X. E.

10.1101/2023.06.05.543407 — neuroscience — Posted on 2023-06-06

3731 A Connectome of the Male Drosophila Ventral Nerve Cord

Takemura, S.-y.; Hayworth, K. J.; Huang, G. B.; Januszewski, M.; Lu, Z.; Marin, E. C.; Preibisch, S.; Xu, C. S.; Bogovic, J.; Champion, A. S.; Cheong, H. S. J.; Costa, M.; Eichler, K.; Katz, W.; Knecht, C.; Li, F.; Morris, B. J.; Ordish, C.; Rivlin, P. K.; Schlegel, P.; Shinomiya, K.; Sturner, T.; Zhao, T.; Badalamente, G.; Bailey, D.; Brooks, P.; Canino, B. S.; Clements, J.; Cook, M.; Duclos, O.; Dunne, C. R.; Fairbanks, K.; Fang, S.; Finley-May, S.; Francis, A.; George, R.; Gkantia, M.; Harrington, K.; Hopkins, G. P.; Hsu, J.; Hubbard, P. M.; Javier, A.; Kainmueller, D.; Korff, W.; Kovalyak,

10.1101/2023.06.05.543757 — neuroscience — Posted on 2023-06-06

3732 Autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes.

Fazel Darbandi, S.; An, J. Y.; Lim, K.; Page, N. F.; Liang, L.; Ypsilanti, A.; Markenscoff-Papadimitriou, E.; State, M. W.; Nord, A. S.; Sanders, S. J.; Rubenstein, J. L. R.

10.1101/2022.10.17.512583 — genomics — Posted on 2023-06-05

3733 Mutation in mitochondrial chaperone TRAP1 results in male-specific autism

Rydzanicz, M.; Kuzniewska, B.; Magnowska, M.; Wojtowicz, T.; Borsuk, E.; Gewartowska, O.; Gruchota, J.; Hojka, A.; Milek, J.; Stawikowska, A.; Wardaszka, P.; Chojnicka, I.; Kondrakiewicz, L.; Puscian, A.; Knapska, E.; Dziembowski, A.; Ploski, R.; Dziembowska, M.

10.1101/2023.06.02.543381 — neuroscience — Posted on 2023-06-06

3734 Neuropeptides with different cellular targets elicit similar output in a central pattern generating circuit

Cronin, E. M.; Schneider, A. C.; Nadim, F.; Bucher, D.

10.1101/2023.06.05.543756 — neuroscience — Posted on 2023-06-06

3735 Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states

Gazestani, V. H.; Kamath, T.; Nadaf, N. M.; Burris, S.; Rooney, B.; Junkkari, A.; Vanderburg, C.; Rauramaa, T.; Therrien, M.; Tegtmeyer, M.; Herukka, S.-K.; Abdulraouf, A.; Marsh, S.; Malm, T.; Hiltunen, M.; Nehme, R.; Stevens, B.; Leinonen, V.; Macosko, E. Z.

10.1101/2023.06.03.543569 — genomics — Posted on 2023-06-05

3736 Gene regulation modules in non-alcoholic fatty liver disease revealed by single-nucleus ATAC-seq

Takeuchi, F.; Liang, Y.-Q.; Shimizu-Furusawa, H.; Isono, M.; Ang, M. Y.; Mori, K.; Mori, T.; Kakazu, E.; Yoshio, S.; Kato, N.

10.1101/2022.07.12.499681 — genomics — Posted on 2023-06-05

3737 Fitness effects of mutations to SARS-CoV-2 proteins

Bloom, J. D.; Neher, R. A.

10.1101/2023.01.30.526314 — evolutionary biology — Posted on 2023-06-06

3738 GDF3 is an obesity-induced regulator of TGFβ superfamily signaling

Ramachandran, D.; Kotikalapudi, N.; Gipson, G. R.; Troncone, L.; Vestal, K.; Maridas, D. E.; Gulko, A.; Tsai, L. T.; Rosen, V.; Yu, P. B.; Thompson, T. B.; Banks, A. S.

10.1101/2022.11.07.515236 — cell biology — Posted on 2023-06-06

3739 Shared gene targets of the ATF4 and p53 transcriptional networks

Baniulyte, G.; Durham, S. A.; Merchant, L. E.; Sammons, M. A.

10.1101/2023.03.15.532778 — molecular biology — Posted on 2023-06-05

3740 A mechanistic understanding of the modes of Ca2+ ion binding to the SARS-CoV-1 fusion peptide and their role in the dynamics of host membrane penetration

Carten, J.; Khelashvili, G.; Bidon, M. K.; Straus, M.; Tang, T.; Jaimes, J. A.; Weinstein, H.; Whittaker, G.; Daniel, S.

10.1101/2022.03.03.482731 — microbiology — Posted on 2023-06-06

3741 CD8+ T-cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by clonal replacement

Aoki, H.; Kitabatake, M.; Abe, H.; Xu, P.; Tsunoda, M.; Shichino, S.; Hara, A.; Ouji-Sageshima, N.; Motozono, C.; Ito, T.; Matsushima, K.; Ueha, S.

10.1101/2022.08.27.504955 — immunology — Posted on 2023-06-06

3742 Emergence of robust global modules from local interactions and smooth gradients

Khona, M.; Chandra, S.; Fiete, I.

10.1101/2021.10.28.466284 — neuroscience — Posted on 2023-06-06

3743 Effect of Terpenes from Poria Cocos: Verifying Modes of Action against Alzheimer's disease Using Molecular Docking, Drug-induced Transcriptomes and Diffusion Network

Park, M.; Lee, S.-Y.; Lee, H.; Yi, J.-M.

10.1101/2023.06.01.543358 — bioinformatics — Posted on 2023-06-06

3744 Haplotype-resolve genome assembly and resequencing provide insights into the origin and domestication of modern rose

Zhang, Z.; Liu, Y.; Yang, T.; Wu, S.; Sun, H.; Wu, J.; Li, Y.; Zheng, Y.; Ren, H.; Yang, Y.; Shi, S.; Wang, W.; Pan, Q.; Lian, L.; Duan, S.; Zhu, Y.; Cai, Y.; Zhou, H.; Zhang, H.; Tang, K.; Cui, J.; Gao, D.; Chen, L.; Jiang, Y.; Sun, X.; Zhou, X.; Fei, Z.; Ma, N.; Gao, J.

10.1101/2023.06.02.543351 — genomics — Posted on 2023-06-05

3745 SNVstory: A dockerized algorithm for rapid and accurate inference of sub-continental ancestry

Bollas, A. E.; Rajkovic, A.; Ceyhan, D.; Gaither, J. B.; Mardis, E. R.; White, P.

10.1101/2023.06.02.543369 — genomics — Posted on 2023-06-05

3746 Ryegrass mottle virus complete genome determination and development of infectious cDNA by combining two methods - 3' RACE and 5' RACE-seq

Balke, I.; Silamikelis, I.; Radovica-Spalvina, I.; Zeltina, V.; Resevica, G.; Fridmanis, D.; Zeltins, A.

10.1101/2023.06.04.543628 — molecular biology — Posted on 2023-06-05

3747 Respiratory syncytial virus directly binds miR-26, miR-27, and let-7 to de-repress gene targets through canonical and non-canonical mechanisms

Ressel, S.; Kumar, S.; Bermudez-Barrientos, J. R.; Gordon, K.; Lane, J.; Wu, J.; Abreu-Goodger, C.; Schwarze, J.; Buck, A. H.

10.1101/2023.06.05.543706 — molecular biology — Posted on 2023-06-05

3748 BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolism

Zhang, Z.; Liao, Q.; Pan, T.; Yu, L.; Luo, Z.; Su, S.; Liu, S.; Hou, M.; Li, Y.; Damba, T.; Liang, Y.; Zhou, L.

10.1101/2023.04.18.537352 — molecular biology — Posted on 2023-06-06

3749 Streptomyces alleviate abiotic stress in plant by producing pteridic acids

Yang, Z.; Stroebech, E.; Qiao, Y.; Konakalla, N. C.; Harris, P.; Peschel, G.; Rosenbaum, M.; Weber, T.; Andreasson, E.; Ding, L.

10.1101/2022.11.18.517137 — microbiology — Posted on 2023-06-05

3750 Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria

Poulton, N. C.; DeJesus, M. A.; Munsamy-Govender, V.; Roberts, C. G.; Azadian, Z. A.; Bosch, B.; Lin, K. M.; Li, S.; Rock, J. M.

10.1101/2023.06.02.543512 — microbiology — Posted on 2023-06-05

3751 NIRis: A low-cost, versatile imaging system for NIR fluorescence detection of phototrophic cell colonies used in science and education

Franz, O.; Häkkänen, H.; Kovanen, S.; Heikkilä-Huhta, K.; Nissinen, R.; Ihalainen, J. A.

10.1101/2023.05.31.543100 — microbiology — Posted on 2023-06-05

3752 Global diversity of enterococci and description of 18 novel species

Schwartzman, J. A.; Lebreton, F.; Salamzade, R.; Martin, M. J.; Schaufler, K.; Urhan, A.; Abeel, T.; Camargo, I. L. B. C.; Sgardioli, B. F.; Prichula, J.; Frazzon, A. P. G.; Van Tyne, D.; Treinish, G.; Innis, C. J.; Wagenaar, J. A.; Whipple, R. M.; Manson, A. L.; Earl, A. M.; Gilmore, M. S.

10.1101/2023.05.18.540996 — microbiology — Posted on 2023-06-05

3753 Expanded diversity of hemoplasmas in rare and undersampled Neotropical bats

Volokhov, D.; Lock, L.; Dyer, K.; DeAnglis, I.; Andrews, B.; Downs, C.; Fenton, B.; Simmons, N. B.; Becker, D.

10.1101/2023.06.05.543748 — microbiology — Posted on 2023-06-06

3754 A comparison of software for analysis of rare and common short tandem repeat (STR) variation using human genome sequences from clinical and population-based samples

Oketch, J. W.; Wain, L. V.; Hollox, E. J.

10.1101/2022.05.25.493473 — genomics — Posted on 2023-06-06

3755 Functional characterization of helminth-associated Clostridia reveals covariates of Treg differentiation

Sargsian, S.; Lejeune, A.; Ercelen, D.; Jin, W.-B.; Varghese, A.; Loke, P.; Lim, Y. A. L.; Guo, C.-J.; Cadwell, K.

10.1101/2023.06.05.543751 — microbiology — Posted on 2023-06-05

3756 Stable Structures or poly(A)-binding protein loading protect cellular and viral RNAs against ISG20-mediated decay

Louvat, C.; Deymier, S.; Nguyen, X.-N.; Labaronne, E.; Noy, K.; Cariou, M.; Corbin, A.; Mateo, M.; Ricci, E. P.; Fiorini, F.; Cimarelli, A.

10.1101/2023.06.05.543696 — microbiology — Posted on 2023-06-05

3757 Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states

Varga, Z. K.; Pejtsik, D.; Toth, M.; Balogh, Z.; Aliczki, M.; Szente, L.; Balla, G. Y.; Kontra, L.; Eckert, Z.; Zsolt, B.; Mikics, E.

10.1101/2023.06.01.543235 — neuroscience — Posted on 2023-06-06

3758 Insights on Poster Preparation Practices in Life Sciences

Jambor, H.

10.1101/2020.10.08.331413 — scientific communication and education — Posted on 2023-06-06

3759 Near chromosome-level genome assembly of the microsporidium Hamiltosporidium tvaerminnensis

Angst, P.; Pombert, J.-F.; Ebert, D.; Fields, P. D.

10.1101/2023.06.02.543461 — genomics — Posted on 2023-06-06

3760 Demographically explicit scans for barriers to gene flow using gIMble

Laetsch, D. R.; Bisschop, G.; Martin, S. H.; Aeschbacher, S.; Setter, D.; Lohse, K.

10.1101/2022.10.27.514110 — evolutionary biology — Posted on 2023-06-06

3761 Natural Silencing of Quorum-Sensing Activity Protects Vibrio parahaemolyticus from Lysis by an Autoinducer-Detecting Phage

Duddy, O.; Silpe, J.; Fei, C.; Bassler, B. L.

10.1101/2023.06.05.543668 — microbiology — Posted on 2023-06-05

3762 Pseudomonas aeruginosa senses and responds to epithelial potassium flux via Kdp operon to promote biofilm biogenesis

Rapsinski, G. J.; Hill, M.; Yarrington, K. D.; Haas, A. L.; D'Amico, E. J.; Armbruster, C. R.; Zemke, A.; Limoli, D.; Bomberger, J.

10.1101/2023.06.05.543669 — microbiology — Posted on 2023-06-06

3763 Boosting variant-calling performance with multi-platform sequencing data using Clair3-MP

Yu, H.; Zheng, Z.; Su, J.; Lam, T.-W.; Luo, R.

10.1101/2023.05.31.543184 — bioinformatics — Posted on 2023-06-06

3764 Full-field strain distribution in hierarchical electrospun nanofibrous Poly-L(lactic) acid and Collagen based scaffolds for tendon and ligament tissue regeneration: a multiscale study

Sensini, A.; Stamati, O.; Marchiori, G.; Sancisi, N.; Gotti, C.; Giavaresi, G.; Cristofolini, L.; Focarete, M. L.; Zucchelli, A.; Tozzi, G.

10.1101/2023.06.01.543145 — bioengineering — Posted on 2023-06-06

3765 Top-down Proteomics of 10,000 Single Brain Cells

Su, P.; Hollas, M. A.; Rubakhin, S.; Butun, F. A.; Greer, J. B.; Early, B. P.; Fellers, R. T.; Caldwell, M. A.; Sweedler, J. V.; Kafader, J. O.; Kelleher, N. L.

10.1101/2023.05.31.543176 — biochemistry — Posted on 2023-06-06

3766 Almond rhizosphere viral, prokaryotic, and fungal communities differed significantly among four California orchards and in comparison to bulk soil communities

ter Horst, A. M.; Adebiyi, T. V.; Hernandez, D. A.; Fudyma, J. D.; Emerson, J. B.

10.1101/2023.06.03.543555 — ecology — Posted on 2023-06-06

3767 HDAC4-mediated deacetylation of GSDMD prevents pyroptosis by inhibiting GSDMD ubiquitination

Xu, W.; Li, X.; Li, D.; Fu, X.; Chen, N.; Lv, Q.; Yuhua, S.; He, S.; Dong, L.; Yang, Y.; Shi, F.

10.1101/2023.06.02.543413 — cell biology — Posted on 2023-06-06

3768 Enhanced fungal specificity and in vivo therapeutic efficacy of a C-22 modified FK520 analog against C. neoformans

Rivera, A.; Lim, W.; Park, E.; Dome, P. A.; Hoy, M. J.; Spasojevic, I.; Sun, S.; Floyd Averette, A.; Pina-Oviedo, S.; Juvvadi, P. R.; Steinbach, W. J.; Ciofani, M.; Hong, J.; Heitman, J.

10.1101/2023.06.05.543712 — microbiology — Posted on 2023-06-05

3769 The apoplastic space of two wheat genotypes provide highly different environment for pathogen colonization: Insights from proteome and microbiome profiling

Francisco, C. S.; Abuhhalaf, M.; Igelmann, C.; Gustke, J.; Habig, M.; Cassidy, L.; Tholey, A.; Stukenbrock, E. H.

10.1101/2023.06.05.543792 — microbiology — Posted on 2023-06-05

3770 Tamarix articulata extract offers protection against toxicity induced by beauty products in Hs27 human skin fibroblasts

ALNUQAYDAN, A. M.; Zainy, F. M. A.; Almutary, A. G.; Sadier, N. S.-; Rah, B. M.

10.1101/2023.05.30.542982 — pharmacology and toxicology — Posted on 2023-06-06

3771 Eosinophils exert direct and indirect anti-tumorigenic effects in the development of esophageal squamous cell carcinoma

Jacobse, J.; Aziz, Z.; Sun, L.; Chaparro, J.; Pilat, J. M.; Kwag, A.; Buendia, M.; Wimbiscus, M.; Nasu, M.; Saito, T.; Mine, S.; Orita, H.; Revetta, F.; Short, S.; Washington, M. K.; Hiremath, G.; Gibson, M.; Coburn, L. A.; Koyama, T.; Goettel, J.; Williams, C.; Choksi, Y. A.

10.1101/2023.06.01.543287 — cancer biology — Posted on 2023-06-05

3772 Zoledronic acid improves bone quality and muscle function in a high bone turnover state

Trivedi, T.; Manaa, M.; John, S.; Reiken, S.; Murthy, S.; Pagnotti, G. M.; Dole, N. S.; She, Y.; Suresh, S.; Hain, B. A.; Regan, J.; Ofer, R.; Wright, L.; Robling, A.; Cao, X.; Alliston, T.; Marks, A. R.; Waning, D. L.; Mohammad, K. S.; Guise, T. A.

10.1101/2023.06.01.543305 — cancer biology — Posted on 2023-06-05

3773 Forecasting fish recruitment using machine learning methods: A case study of arabesque greenling

Okamura, H.; Morita, S.; Kuroda, H.

10.1101/2023.06.02.543365 — ecology — Posted on 2023-06-06

3774 The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions

Xie, L.; Wu, G.; Liu, X.; Duan, X.; Zhou, K.; Li, H.; Ning, W.

10.1101/2023.06.05.543720 — cell biology — Posted on 2023-06-06

3775 Co-infecting phages impede each other's entry into the cell

Nguyen, T. V. P.; Wu, Y.; Yao, T.; Trinh, J. T.; Zeng, L.; Chemla, Y. R.; Golding, I.

10.1101/2023.06.05.543643 — microbiology — Posted on 2023-06-05

3776 Activation of programmed cell death and counter-defense functions of phage accessory genes

Silas, S.; Carion, H.; Makarova, K. S.; Laderman, E.; Godinez, D. S.; Johnson, M.; Fossati, A.; Swaney, D.; Bocek, M.; Koonin, E. V.; Bondy-Denomy, J.

10.1101/2023.04.06.535777 — microbiology — Posted on 2023-06-05

3777 A mutation-mediated host shift drives Avian paramyxovirus type 1 evolution

Chang, H.; Feng, S.; Tang, X.; Wang, Z.; Su, W.; Han, S.; Li, G.; Hu, B.; Jing, S.; Wang, B.; Xiang, C.; Xing, Y.; Wang, Y.; Lu, J.; He, h.

10.1101/2023.06.05.543675 — microbiology — Posted on 2023-06-05

3778 ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

Wang, S.; Bohnert, V.; Joseph, A. J.; Sudaryo, V.; Swinderman, J.; Yu, F. B.; Lyu, X.; Skariah, G.; Subramanyam, V.; Gilbert, L. A.; Goodarzi, H.; Li, L.

10.1101/2023.06.01.543353 — cancer biology — Posted on 2023-06-05

3779 Monocyte Adhesion and Transmigration Through Endothelium Following Cardiopulmonary Bypass Shearing is Mediated by IL-8 Signaling

Zhou, H.; Tu, L. N.; Giachelli, C. M.; Nigam, V.; Scatena, M.

10.1101/2023.06.05.543811 — cell biology — Posted on 2023-06-06

3780 Yeast PRPP amidotransferase assembles into fine granules to promote de novo purine synthesis through intermolecular substrate channeling

Takaine, M.; Morita, R.

10.1101/2023.06.05.543815 — cell biology — Posted on 2023-06-06

3781 Expanded diversity of hemoplasmas in rare and undersampled Neotropical bats

Volokhov, D.; Lock, L.; Dyer, K.; DeAnglis, I.; Andrews, B.; Downs, C.; Fenton, B.; Simmons, N. B.; Becker, D.

10.1101/2023.06.05.543748 — microbiology — Posted on 2023-06-05

3782 Meta-omics analyses of dual substrate enrichment culturing of nitrous oxide respiring bacteria suggest that attachment and complex polysaccharide utilisation contributed to the ability of Cloacibacterium strains to reach dominance

Vick, S. H. W.; Jonassen, K. R.; Arntzen, M.; Lycus, P.; Bakken, L. R.

10.1101/2023.06.04.543644 — microbiology — Posted on 2023-06-05

3783 Stress- and phospholipid signalling responses in Arabidopsis PLC4-KO and -overexpression lines under salt- and osmotic stress

Hooren, M. v.; Darwish, E.; Munnik, T.

10.1101/2023.06.02.543366 — plant biology — Posted on 2023-06-06

3784 Nociception in chicken embryos, Part I: Analysis of cardiovascular responses to a mechanical noxious stimulus

Weiss, L.; Saller, A. M.; Werner, J.; Suess, S. C.; Reiser, J.; Kollmansperger, S.; Anders, M.; Fenzl, T.; Schusser, B.; Baumgartner, C.

10.1101/2023.04.14.536899 — physiology — Posted on 2023-06-06

3785 IL-1R signaling drives enteric glia-macrophage interaction in colorectal cancer progression

van Baarle, L.; De Simone, V.; Schneider, L.; Santhosh, S.; Abdurahiman, S.; Biscu, F.; Schneider, R.; Zanoletti, L.; Verbandt, S.; Hu, Z.; Stakenborg, M.; Ke, B.-J.; Garcia-Reyes, B.; Henn, J.; Toma, M.; Vanmechelen, M.; De Smet, F.; Ibiza, S.; Tejpar, S.; Wehner, S.; Matteoli, G.

10.1101/2023.06.01.543246 — cancer biology — Posted on 2023-06-05

3786 Isolation and characterization of a novel hormone receptor positive mammary adenocarcinoma MCa-P1362 with stromal drivers of tumor growth, metastasis, and drug resistance

Jana, S.; Li, W.; Lei, P.-J.; Wang, Z.; Huang, P.; Jones, D.

10.1101/2023.06.02.543434 — cancer biology — Posted on 2023-06-06

3787 Metallo-Supramolecular Branched Polymer Protects Particles from Air-water Interface in Single-Particle Cryo-Electron Microscopy

Xu, Y.; Qin, Y.; Wang, L.; Zhang, Y.; Wang, Y.; Dang, S.

10.1101/2022.06.08.495397 — biophysics — Posted on 2023-06-06

3788 An obligate intracellular bacterial pathogen forms a direct, interkingdom membrane contact site

Acevedo-Sanchez, Y.; Woida, P. J.; Kraemer, S.; Lamason, R. L.

10.1101/2023.06.05.543771 — cell biology — Posted on 2023-06-06

3789 NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62

Furthmann, N.; Angersbach, L.; Bader, V.; Blusch, A.; Goel, S.; Sanchez-Vicente, A.; Krause, L. J.; Grover, P.; Trinkaus, V. A.; van Well, E. M.; Jaugstetter, M.; Tschulik, K.; Damgaard, R. B.; Saft, C.; Ellrichmann, G.; Gold, R.; Koch, A.; Englert, B.; Glatzel, M.; Hartl, F.-U.; Nakamura, K.; Christine, C.; Huang, E. J.; Tatzelt, J.; Winklhofer, K. F.

10.1101/2023.06.05.543428 — cell biology — Posted on 2023-06-06

3790 Metabolic capabilities are highly conserved among human nasal-associated Corynebacterium species in pangenomic analyses

Tran, T. H.; Roberts, A. Q.; F. Escapa, I.; Gao, W.; Segre, J. A.; Kong, H. H.; Conlan, S.; Kelly, M.; Lemon, K. P.

10.1101/2023.06.05.543719 — microbiology — Posted on 2023-06-05

3791 Substrate availability and dietary fibre regulate metabolism of tryptophan by human gut microbes

Sinha, A. K.; Laursen, M. F.; Brinck, J. E.; Rybtke, M. L.; Pedersen, M.; Roager, H. M.; Licht, T. R.

10.1101/2023.06.05.543658 — microbiology — Posted on 2023-06-05

3792 Discovery and engineering of hypercompact epigenetic modulators for durable gene activation

Carosso, G. A.; Yeo, R. W.; Gainous, T. B.; Jawaid, Z.; Yang, X.; Cutillas, V.; Qi, L. S.; Daley, T. P.; Hart, D. O.

10.1101/2023.06.02.543492 — synthetic biology — Posted on 2023-06-05

3793 Cancer drug sensitivity prediction from routine histology images

Dawood, M.; Vu, Q. D.; Young, L.; Branson, K.; Jones, L.; Rajpoot, N.; Minhas, F. u. A. A.

10.1101/2023.06.03.543536 — cancer biology — Posted on 2023-06-06

3794 Identification of domains in Plasmodium falciparum proteins of unknown function using DALI search on Alphafold predictions

Spielmann, T.; Behrens, H. M.

10.1101/2023.06.05.543710 — cell biology — Posted on 2023-06-06

3795 Apical polarity and actomyosin dynamics regulate Hippo signaling by controlling Kibra subcellular localization

Tokamov, S. A.; Nouri, N.; Rich, A.; Buiter, S.; Glotzer, M.; Fehon, R. G.

10.1101/2023.06.05.543736 — cell biology — Posted on 2023-06-06

3796 A SMART method for efficiently isolating monoclonal antibodies from individual rhesus macaque memory B cells

Weinfurter, J. T.; Bennett, S. N.; Reynolds, M.

10.1101/2023.06.02.543510 — immunology — Posted on 2023-06-05

3797 Single-cell transcriptome and TCR analysis of human Cytomegalovirus (hCMV)-specific T cell memory reveals effector and pre-effectors of CD8+ and CD4+ cytotoxic T cells

Kar, R.; Chattopadhyay, S.; Sharma, A.; Sharma, K.; Arimbasseri, G. A. S.; Patil, V. S.

10.1101/2023.06.02.543443 — immunology — Posted on 2023-06-05

3798 Study of auxin metabolism using stable isotope labeling and LCMS; evidence for in planta auxin decarboxylation pathway.

Dobrev, P. I.; Filepova, R.; Lacek, J.; Vondrakova, Z.; Muller, K.; Marsik, P.; Drasarova, L.; Talacko, P.; Hosek, P.; Petrasek, J.

10.1101/2023.06.02.543384 — plant biology — Posted on 2023-06-06

3799 High-efficiency digitally scanned light-sheet fluorescence lifetime microscopy (DSLM-FLIM)

Nutt, K. J.; Olesker, D.; McGhee, E.; Hungerford, G.; Leburn, C. G.; Taylor, J. M.

10.1101/2023.06.02.543377 — biophysics — Posted on 2023-06-06

3800 DNA methylation signatures of early life adversity are exposure-dependent in wild baboons

Anderson, J. A.; Lin, D.; Lea, A. J.; Johnston, R. A.; Voyles, T.; Akinyi, M. Y.; Archie, E.; Alberts, S. C.; Tung, J.

10.1101/2023.06.05.542485 — genomics — Posted on 2023-06-05

3801 A Unified Pipeline for FISH Spatial Transcriptomics

Cisar, C.; Keener, N.; Ruffalo, M.; Paten, B.

10.1101/2023.02.17.529010 — genomics — Posted on 2023-06-05

3802 Haploid-resolved and chromosome-scale genome assembly in Citrus unshiu and its parental species, C. nobilis and C. kinokuni

Isobe, S.; Fujii, H.; Shirasawa, K.; Kawahara, Y.; Endo, T.; Shimada, T.

10.1101/2023.06.02.543356 — genomics — Posted on 2023-06-05

3803 Functionally and metabolically divergent melanoma-associated macrophages originate from common bone-marrow precursors

Pizzurro, G. A.; Bridges, K.; Jiang, X.; Vidyarthi, A.; Miller-Jensen, K.; Colegio, O. R.

10.1101/2023.06.02.543515 — immunology — Posted on 2023-06-05

3804 Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.

Jha, D.; Al-Taie, Z.; Krek, A.; Eshghi, S. T.; Fantou, A.; Laurent, T.; Tankelevich, M.; Cao, X.; Meringer, H.; Livanos, A.; Tokuyama, M.; Cossarini, F.; Bourreille, A.; Josien, R.; Hou, R.; Canales-Herrerias, P.; Ungaro, R. C.; Kayal, M.; Marion, J.; Polydorides, A. D.; Ko, H. M.; D'souza, D.; Merand, R.; Kim-Schulze, S.; Hackney, J. A.; Nguyen, A.; McBride, J. M.; Yuan, G.-C.; Colombel, J.-F.; Martin, J. C.; Argmann, C.; Suarez-Farinas, M.; Petralia, F.; Mehandru, S.

10.1101/2023.06.02.542863 — immunology — Posted on 2023-06-05

3805 Study of auxin metabolism using stable isotope labeling and LCMS; evidence for in planta auxin decarboxylation pathway.

Dobrev, P. I.; Filepova, R.; Lacek, J.; Vondrakova, Z.; Muller, K.; Marsik, P.; Drasarova, L.; Talacko, P.; Hosek, P.; Petrasek, J.

10.1101/2023.06.02.543384 — plant biology — Posted on 2023-06-05

3806 Inhibition of BCR::ABL1 tyrosine kinase activity Aids in the Generation of Stable Chronic Myeloid Leukemia Induced Pluripotent Stem Cells

Benjamin, E. S. B.; Babu, D.; Joshi, G.; Rajamani, B. M.; Nandy, K.; Rani, S.; Anandhan, S.; PremKumar, C.; Maddali, M.; Abraham, A.; Velayudhan, S. R.; Balasubramanian, P.

10.1101/2023.06.01.543015 — cancer biology — Posted on 2023-06-05

3807 A metabolic crosstalk between liposarcoma and muscle sustains tumor growth

Manteaux, G.; Prieto Romero, J.; Gayte, L.; Riquier Morcant, B.; Amsel, A.; Jacq, S.; Cisse, M. Y.; Perot, G.; Chibon, F.; Pomies, P.; Firmin, N.; Carrere, S.; Riscal, R.; Linares, L. K.

10.1101/2023.06.02.543362 — cancer biology — Posted on 2023-06-05

3808 Cancer initiation is influenced by sex-biased tissue environment or imbalanced hormones

Zhang, F.; Deng, M.

10.1101/2023.05.20.541565 — cancer biology — Posted on 2023-06-05

3809 GeneMark-ETP: Automatic Gene Finding in Eukaryotic Genomes in Consistence with Extrinsic Data

Bruna, T.; Lomsadze, A.; Borodovsky, M.

10.1101/2023.01.13.524024 — bioinformatics — Posted on 2023-06-05

3810 Investigating pedigree- and SNP-associated components of heritability in a wild population of Soay sheep

James, C.; Pemberton, J. M.; Navarro, P.; Knott, S.

10.1101/2023.06.02.543397 — genetics — Posted on 2023-06-05

3811 Factorizing polygenic epistasis improves prediction and uncovers biological pathways in complex traits

Tang, D.; Freudenberg, J.; Dahl, A.

10.1101/2022.11.29.518075 — genetics — Posted on 2023-06-05

3812 The evolution of RNA interference among Metazoa

Formaggioni, A.; Cavalli, G.; Hamada, M.; Sakamoto, T.; Plazzi, F.; Passamonti, M.

10.1101/2023.05.08.538551 — evolutionary biology — Posted on 2023-06-05

3813 Difference in determinants and changing patterns of plant community composition with and without grazing across semi-arid and arid regions in Mongolian steppe

Ishii, N. I.; Nishimura, I.; Qi, Y.; Batdelger, G.; Kagami, M.; Takimoto, G.; Sasaki, T.

10.1101/2022.12.24.521851 — ecology — Posted on 2023-06-05

3814 Systematic review of residual toxicity studies of pesticides to bees and comparison to language on pesticide labels using data from studies and the Environmental Protection Agency.

Swanson, L.; Melathopoulos, A.; Bucy, M.

10.1101/2023.06.05.543089 — ecology — Posted on 2023-06-05

3815 Temporally Specific Gene Expression and Chromatin Remodeling Programs Regulate a Conserved Pdyn Enhancer

Phillips, R. A.; Wan, E.; Tuscher, J. J.; Reid, D.; Ianov, L.; Day, J. J.

10.1101/2023.06.02.543489 — neuroscience — Posted on 2023-06-05

3816 Cortico-cerebellar coordination facilitates neuroprosthetic control

Abbasi, A.; Rangwani, R.; Bowen, D. W.; Fealy, A. W.; Danielsen, N. P.; Gulati, T.

10.1101/2022.07.07.499221 — neuroscience — Posted on 2023-06-05

3817 Olfactory cortex output pathways exhibit robust differences in their ability to drive learned aversion

Vieira, I.; Bryzgalov, D.

10.1101/2023.06.04.541965 — neuroscience — Posted on 2023-06-05

3818 Phosphoprotein dynamics of interacting tumor and T cells by HySic

Ibanez-Molero, S.; Pruijs, J.; Atmopawiro, A.; Wang, F.; Altelaar, M. E.; Peeper, D. S.; Stecker, K. E.

10.1101/2023.06.05.541905 — cancer biology — Posted on 2023-06-05

3819 RESTORING CONNEXIN-36 FUNCTION IN DIABETOGENIC ENVIRONMENTS PRECLUDES MOUSE AND HUMAN ISLET DYSFUNCTION

St Clair, J. R.; Westacott, M. J.; Miranda, J. G.; Farnsworth, N. L.; Kravets, V.; Schleicher, W. E.; Dwulet, J. M.; Levitt, C. H.; Heintz, A.; Ludin, N. W. F.; Benninger, R. K.

10.1101/2020.11.03.366179 — biophysics — Posted on 2023-06-05

3820 ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation

Banerjee, C.; Mehra, D.; Song, D.; Mancebo, A.; Kim, D.-H.; Puchner, E. M.

10.1101/2020.07.03.187336 — biophysics — Posted on 2023-06-05

3821 Illuminating Dark Proteins using Reactome Pathways

Brunson, T.; Sanati, N.; Matthews, L.; Haw, R.; Beavers, D.; Shorser, S.; Sevilla, C.; Viteri, G.; Conley, P.; Rothfels, K.; Hermjakob, H.; Stein, L.; D'Eustachio, P.; Wu, G.

10.1101/2023.06.05.543335 — bioinformatics — Posted on 2023-06-05

3822 Contrasting responses to aridity by different-sized decomposers cause similar decomposition rates across a precipitation gradient

Torsekar, V. R.; Sagi, N.; Johnson, A. D.; Hawlena, Y.; Gavish-Regev, E.; Hawlena, D.

10.1101/2023.06.04.541603 — ecology — Posted on 2023-06-05

3823 Predator learning can resolve the paradox of local warning signal diversity

Kuo, C.-Y.

10.1101/2023.05.04.539348 — ecology — Posted on 2023-06-05

3824 Hyperaccumulation of Vanadium in animals: two sponges compete with urochordates

de Pao Mendonca, K.; Chaurand, P.; Campos, A.; Angeletti, B.; Rovezzi, M.; Delage, L.; Borchiellini, C.; Le Bivic, A.; issartel, j.; RENARD, E.; Levard, C.

10.1101/2023.06.02.543482 — ecology — Posted on 2023-06-05

3825 Accurate neuroprosthetic control through latent state transition training

Agudelo-Toro, A.; Michaels, J. A.; Sheng, W.-A.; Scherberger, H.

10.1101/2023.06.02.543242 — neuroscience — Posted on 2023-06-05

3826 An exploratory study of gastrointestinal redox biomarkers in the presymptomatic and symptomatic Tg2576 mouse model of familial Alzheimer's disease - phenotypic correlates and the effects of chronic oral D-galactose

Homolak, J.; Babic Perhoc, A.; Knezovic, A.; Osmanovic Barilar, J.; Virag, D.; Salkovic-Petrisic, M.

10.1101/2023.06.03.542513 — neuroscience — Posted on 2023-06-05

3827 Cryo-EM structure of the human G-protein coupled receptor 1 (GPR1) - Gi protein complex bound to the chemerin C-terminal nonapeptide

Liu, A.; Liu, Y.; Chen, G.; Lyu, W.; Wang, J.; Ye, F.; Zhu, L.; Du, Y.; Ye, R. D.

10.1101/2023.06.03.543554 — pharmacology and toxicology — Posted on 2023-06-05

3828 Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes

Chua, G. N. L.; Watters, J. W.; Olinares, P. D. B.; Luo, J. A.; Chait, B. T.; Liu, S.

10.1101/2023.06.02.543478 — biophysics — Posted on 2023-06-05

3829 VitTCR: A deep learning method for peptide recognition prediction

Jiang, M.; Yu, Z.; Lan, X.

10.1101/2023.06.02.543411 — bioinformatics — Posted on 2023-06-05

3830 Stability of navigation in catheter-based endovascular procedures

Hartquist, C. M.; Lee, J. V.; Qiu, M. Y.; Suskin, C.; Chandrasekaran, V.; Lowe, H. R.; Zayed, M. A.; Osbun, J. W.; Genin, G. M.

10.1101/2023.06.02.543219 — bioengineering — Posted on 2023-06-05

3831 Structural basis of EHEP-mediated offense against phlorotannin-induced defense from brown algae to protect akuBGL activity

Sun, X.; Ye, Y.; Sakurai, N.; Wang, H.; Kato, K.; Yu, J.; Yuasa, K.; Tsuji, A.; Yao, M.

10.1101/2023.06.04.543649 — biochemistry — Posted on 2023-06-05

3832 Novel genomic offset metrics account for local adaptation in climate suitability forecasts and inform assisted migration

Lachmuth, S.; Capblancq, T.; Prakash, A.; Keller, S. R.; Fitzpatrick, M. C.

10.1101/2023.06.05.541958 — ecology — Posted on 2023-06-05

3833 Microbial Responses to Biochar Soil Amendment and Influential Factors: A Three-level Meta-analysis

Kerner, P.; Struhs, E.; Mirkouei, A.; Aho, K.; Lohse, K. A.; Dungan, R. S.; You, Y.

10.1101/2023.06.02.543269 — ecology — Posted on 2023-06-05

3834 Divergent associations of slow-wave sleep vs. REM sleep with plasma amyloid-beta

Rosenblum, Y.; Pereira, M.; Stange, O.; Weber, F. D.; Bovy, L.; Tzioridou, S.; Lancini, E.; Neville, D. A.; Klein, N.; de Wolff, T.; Stritzke, M.; Kersten, I.; Uhr, M.; Claassen, J. A. H. R.; Steiger, A.; Verbeek, M. M.; Dresler, M.

10.1101/2023.06.02.543111 — neuroscience — Posted on 2023-06-05

3835 An adhesion signaling axis involving Dystroglycan, β1-Integrin and Cas adaptor proteins regulates the establishment of the cortical glial scaffold

Wong, W.; Estep, J. A.; Treptow, A. M.; Rajabli, N.; Jahncke, J. N.; Ubina, T.; Wright, K. M.; Riccomagno, M. M.

10.1101/2022.08.02.502565 — neuroscience — Posted on 2023-06-05

3836 Fear in action: Fear conditioning and alleviation through body movements

Alemany Gonzalez, M.; Wokke, M. E.; Chiba, T.; Narumi, T.; Kaneko, N.; Yokoyama, H.; Watanabe, K.; Nakazawa, K.; Imamizu, H.; Koizumi, A.

10.1101/2022.06.20.496915 — neuroscience — Posted on 2023-06-05

3837 Graph representations of iEEG data for seizure detection with graph neural networks

Diaz-Montiel, A. A.; Lankarany, M.

10.1101/2023.06.02.543277 — neuroscience — Posted on 2023-06-05

3838 Disentangling protein metabolic costs in human cells and tissues.

Chagoyen, M.; Poyatos, J. F.

10.1101/2023.06.05.543683 — systems biology — Posted on 2023-06-05

3839 Small transcriptional differences lead to distinct NF-κB dynamics in quasi-identical cells

Kizilirmak, C.; Monteleone, E.; Garcia-Manteiga, J. M.; Brambilla, F.; Agresti, A.; Bianchi, M. E.; Zambrano, S.

10.1101/2021.12.07.471485 — systems biology — Posted on 2023-06-05

3840 Expanding the toolbox of probiotic Escherichia coli Nissle 1917 for synthetic biology

Ba, F.; Zhang, Y.; Ji, X.; Liu, W.-Q.; Ling, S.; Li, J.

10.1101/2023.06.05.543671 — synthetic biology — Posted on 2023-06-05

3841 Design and assembly of the 117-kb Phaeodactylum tricornutum chloroplast genome

Walker, E. J. L.; Pampuch, M.; Chang, N.; Cochrane, R. R.; Karas, B. J.

10.1101/2023.06.05.543740 — synthetic biology — Posted on 2023-06-05

3842 Engineering the Maize Root Microbiome: A Rapid MoClo Toolkit and Identification of Potential Bacterial Chassis for studying Plant-Microbe Interactions

Van Schaik, J.; Li, Z.; Cheadle, J. B.; Crook, N. C.

10.1101/2023.06.05.543168 — synthetic biology — Posted on 2023-06-05

3843 Bridging Imaging Users to Imaging Analysis - A community survey

Sivagurunathan, S.; Marcotti, S.; Nelson, C. J.; Jones, M. L.; Barry, D. J.; Slater, T. J. A.; Eliceiri, K. W.; Cimini, B. A.

10.1101/2023.06.05.543701 — scientific communication and education — Posted on 2023-06-05

3844 Non-indigenous seaweeds in the Northeast Atlantic Ocean, the Mediterranean Sea and Macaronesia: a critical synthesis of diversity, spatial and temporal patterns

van der Loos, L. M.; Bafort, Q.; Bosch, S.; Ballesteros, E.; Barbara, I.; Bercibar, E.; Blanfune, A.; Bogaert, K.; Bouckenooghe, S.; Boudouresque, C.-F.; Brodie, J.; Cecere, E.; Diaz-Tapia, P.; Engelen, A. H.; Gunnarson, K.; Hamdy Shabaka, S.; Hoffman, R.; Husa, V.; Israel, A.; Karremans, M.; Knoop, J.; Le Gall, L.; Maggs, C. A.; Mineur, F.; Parente, M.; Perk, F.; Petrocelli, A.; Rodriguez-Prieto, C.; Ruitton, S.; Sanson, M.; Serrao, E. A.; Sfriso, A.; Sjotun, K.; Stiger-Pouvreau, V.; Surget, G.; Thibaut, T.; Tsiamis, K.; Van De Weghe, L.; Verlaque, M.; Viard, F.; Vranken, S.; Leliaert, F.; De

10.1101/2023.06.05.543185 — plant biology — Posted on 2023-06-05

3845 Trading acyls and swapping sugars: metabolic innovations in Solanum trichomes

Fiesel, P. D.; Kerwin, R. A.; Jones, A. D.; Last, R. L.

10.1101/2023.06.05.542877 — plant biology — Posted on 2023-06-05

3846 A fungal RNA-dependent RNA polymerase is a novel player in plant infection and cross-kingdom RNA interference

Cheng, A.-P.; Lederer, B.; Oberkofler, L.; Huang, L.; Platten, F.; Dunker, F.; Tisserant, C.; Weiberg, A.

10.1101/2023.06.02.543307 — pathology — Posted on 2023-06-05

3847 Single-molecule studies reveal the off-pathway elemental pause state as a target of streptolydigin inhibition of RNA polymerase and its dramatic enhancement by Gre factors

Arseniev, A.; Panfilov, M.; Pobegalov, G.; Potyseva, A.; Pavlinova, P.; Yakunina, M.; Lee, J.; Borukhov, S.; Severinov, K.; Khodorkovskii, M.

10.1101/2023.06.05.542125 — biophysics — Posted on 2023-06-05

3848 A Genome-Wide Comprehensive Analysis of Nucleosome Positioning in Yeast

Zeitler, L.; Andre, K.; Alberti, A.; Denby Wilkes, C.; Soutourina, J.; Goldar, A.

10.1101/2023.06.02.543396 — bioinformatics — Posted on 2023-06-05

3849 Biochemical characterization of mRNA capping enzyme from Faustovirus

Chan, S. H.; Mole, C. N.; Nye, D.; Mitchell, L.; Dai, N.; Buss, J.; Whipple, J. M.; Kneller, D. W.; Robb, G. B.

10.1101/2023.06.05.542502 — biochemistry — Posted on 2023-06-05

3850 A structural competition involving WDR5 times circadian oscillations

Boergel, A.; Rawleigh, A.; Conrady, M.; Hof, F.; Ricci, K.; Brown, S.; Wolf, E.

10.1101/2023.06.05.543739 — biochemistry — Posted on 2023-06-05

3851 Bacterial mimicry of eukaryotic HECT ubiquitin ligation

Franklin, T. G.; Brzovic, P. S.; Pruneda, J. N.

10.1101/2023.06.05.543783 — biochemistry — Posted on 2023-06-05

3852 Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference

Lobo, V.; Nowak, I.; Fernandez, C.; Correa Muler, A. I.; Westholm, J. O.; Huang, H.-C.; Fabrik, I.; Huynh, H. T.; Kanik, M.; Hartlova, A.; Benhalevy, D.; Angeletti, D.; Sarshad, A. A.

10.1101/2023.06.05.543674 — biochemistry — Posted on 2023-06-05

3853 Specific photoreceptor cell fate pathways are differentially altered in NR2E3-associated diseases

Aisa-Marin, I.; Rovira, Q.; Diaz, N.; Calvo-Lopez, L.; Vaquerizas, J. M.; Marfany, G.

10.1101/2023.06.03.543550 — genetics — Posted on 2023-06-05

3854 Environmentally robust cis-regulatory changes underlie rapid climatic adaptation

Ballinger, M. A.; Mack, K. L.; Durkin, S. M.; Riddell, E. A.; Nachman, M. W.

10.1101/2022.08.29.505745 — evolutionary biology — Posted on 2023-06-05

3855 Cysteine enrichment mediates co-option of uricase in reptilian skin and transition to uricotelism

Mori, G.; Liuzzi, A.; Ronda, L.; Di Palma, M.; Chegkazi, M. S.; Bui, S.; Garcia-Maya, M.; Ragazzini, J.; Malatesta, M.; Della Monica, E.; Rivetti, C.; Antin, P.; Bettati, S.; Steiner, R. A.; Percudani, R.

10.1101/2023.06.02.543418 — evolutionary biology — Posted on 2023-06-05

3856 α-synuclein promotes neuronal dysfunction and death by disrupting the binding of ankyrin to β-spectrin

Maor, G.; Dubreuil, R. R.; Feany, M. B.

10.1101/2023.06.02.543481 — neuroscience — Posted on 2023-06-05

3857 Perivascular spaces in Alzheimer's disease are associated with inflammatory, stress-related, and hypertension biomarkers

Sibilia, F.; Sheikh-Bahaei, N.; Mack, W. J.; Choupan, J.

10.1101/2023.06.02.543504 — neuroscience — Posted on 2023-06-05

3858 Maternal Aggression Driven by the Transient Mobilization of a Dormant Hormone-Sensitive Circuit

Stagkourakis, S.; Williams, P.; Spigolon, G.; Khanal, S.; Ziegler, K.; Heikkinen, L.; Fisone, G.; Broberger, C.

10.1101/2023.02.02.526862 — neuroscience — Posted on 2023-06-05

3859 Broaden the application of Yarrowia Lipolytica synthetic biology tools to explore the potential of Yarrowia clade biodiversity

Park, Y.-K.; Rossignol, T.

10.1101/2023.06.05.543681 — synthetic biology — Posted on 2023-06-05

3860 The senescent mesothelial matrix accentuates colonization by ovarian cancer cells

Thapa, B.; Glimm, T.; Saini, D. K.; Bhat, R.

10.1101/2023.06.02.543239 — cancer biology — Posted on 2023-06-05

3861 Potential involvement of protein phosphatase PP2CA on protein synthesis and cell cycle during SARS-CoV-2 infection. A meta analysis investigation

Otvos, L. P.; Garrito, G. I. M.; Machado, L. E. S. F.

10.1101/2023.06.02.543487 — bioinformatics — Posted on 2023-06-05

3862 Machine Learning-Guided Antibody Engineering That Leverages Domain Knowledge To Overcome The Small Data Problem

Clark, T.; Subramanian, V.; Jayaraman, A.; Fitzpatrick, E.; Gopal, R.; Pentakota, N.; Rurak, T.; Anand, S.; Viglione, A.; Tharakaraman, K.; Raman, R.; Sasisekharan, R.

10.1101/2023.06.02.543458 — bioengineering — Posted on 2023-06-05

3863 Oatmeal and wheat flour as the sources of thyroid peroxidase (TPO), lipoxygenase (LOX) and xanthine oxidase (XO) modulators potentially applicable in the prevention of inflammatory thyroid diseases

Habza-Kowalska, E.; Piwowarczyk, K.; Czyz, J.; Gawlik-Dziki, U.

10.1101/2023.06.05.543703 — biochemistry — Posted on 2023-06-05

3864 Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system

Dhingra, Y.; Sashital, D. G.

10.1101/2023.06.05.543779 — biochemistry — Posted on 2023-06-05

3865 A deep learning-based drug repurposing screening and validation for anti-SARS-CoV-2 compounds by targeting the cell entry mechanism

Yao, Y.; Zhang, Y.; Li, Z.; Chen, Z.; Wang, X.; Li, Z.; Yu, L.; Cheng, X.; Li, W.; Jiang, W.-J.; Wu, H.-J.; Feng, Z.; Sun, J.; Fei, T.

10.1101/2023.06.03.543589 — microbiology — Posted on 2023-06-05

3866 T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity

Kolz, A.; Bauer, I.; de la Rosa del Val, C.; Kavaka, V.; Thomann, A. S.; Schmitz, R.; Kerschensteiner, M.; Beltran, E.; Kawakami, N.; Peters, A.

10.1101/2023.06.01.543004 — immunology — Posted on 2023-06-05

3867 HSP90 inhibitor gedunin impairs glioblastoma proliferation and invasiveness

10.1101/2023.06.02.543101 — pharmacology and toxicology — Posted on 2023-06-05

3868 Predicting drug response from single-cell expression profiles of tumours

Pellecchia, S.; Viscido, G.; Gambardella, G.; Gambardella, G.

10.1101/2023.06.01.543212 — cancer biology — Posted on 2023-06-05

3869 The pharmacoepigenomic landscape of cancer cell lines reveals the epigenetic component of drug sensitivity

Ohnmacht, A. J.; Rajamani, A.; Avar, G.; Kutkaite, G.; Goncalves, E.; Saur, D.; Menden, M. P.

10.1101/2023.06.01.543264 — cancer biology — Posted on 2023-06-05

3870 Antigen perception in T cells by long-term Erk and NFAT signaling dynamics.

Wither, M. J.; White, W. L.; Pendyala, S.; Leanza, P. J.; Fowler, D.; Kueh, H. Y.

10.1101/2023.06.01.543260 — immunology — Posted on 2023-06-05

3871 HDAC1-3 inhibition reduces CCR2 expression and immunosuppressive function of myeloid-derived suppressor cells

Xie, Z.; Okada, Y.; Okuzaki, D.; Okada, N.; Tachibana, M.

10.1101/2023.06.01.543360 — immunology — Posted on 2023-06-05

3872 Global changes in open reading frame dominance of RNAs during cancer initiation and progression

Suenaga, Y.; Kogashi, H.; Nakatani, K.; Lin, J.; Hasegawa, Y.; Kugou, K.; Kawashima, Y.; Furukawa, E.; Okumura, K.; Kita, E.; Wakabayashi, Y.; Kato, M.; Kawazu, M.; Hippo, Y.

10.1101/2023.06.02.543339 — cancer biology — Posted on 2023-06-05

3873 Dynamic chromatin remodeling in cycling human endometrium at single cell level

Vrljicak, P.; Lucas, E. S.; Tryfonos, M.; Muter, J.; Ott, S.; Brosens, J.

10.1101/2023.06.01.543328 — genomics — Posted on 2023-06-05

3874 NINJ1 mediates plasma membrane rupture through formation of nanodisc-like rings

David, L.; Borges, J. P.; Hollingsworth, L. R.; Volchuk, A.; Jansen, I.; Steinberg, B. E.; Wu, H.

10.1101/2023.06.01.543231 — immunology — Posted on 2023-06-05

3875 Impact of Common Modifications on the Antigenic Profile and Glycosylation of Membrane-Expressed HIV-1 Envelope Glycoprotein.

Tong, T.; D'Addabbo, A.; Xu, J.; Chawla, H.; Nguyen, A.; Ochoa, P.; Crispin, M.; Binley, J. M.

10.1101/2023.06.02.543368 — immunology — Posted on 2023-06-05

3876 Computational Studies of Human Sodium/glucose cotransporters: (SGLT1), (SGLT2) and investigation of Human Sirtuins together with Polydatin

FERRARI, I. V.

10.1101/2023.06.01.543288 — cancer biology — Posted on 2023-06-05

Musa, A. A.; Reinsch, N.

10.1101/2023.06.01.543227 — genetics — Posted on 2023-06-05

3878 Scalable projected Light Sheet Microscopy for high-resolution imaging of large samples

Chen, Y.; Gong, C.; Chauhan, S.; De La Cruz, E. D.; Datta, M. S.; Tomer, R.

10.1101/2023.05.31.543173 — neuroscience — Posted on 2023-06-05

3879 Gap junctions arbitrate binocular course control in flies

Pokusaeva, V. O.; Satapathy, R.; Symonova, O.; Joesch, M.

10.1101/2023.05.31.543181 — neuroscience — Posted on 2023-06-05

3880 Structural Insights into Regulation of Insulin Expression Involving i-Motif DNA Structures in the Insulin-Linked Polymorphic Region.

Guneri, D.; Alexandrou, E.; El Omari, K.; Dvorakova, Z.; Chikhale, R. V.; Pike, D.; Waudby, C. A.; Morris, C. J.; Haider, S.; Parkinson, G. N.; Waller, Z. A. E.

10.1101/2023.06.01.543149 — biophysics — Posted on 2023-06-05

3881 The PALB2 DNA binding domain is an intrinsically disordered recombinase.

Kyriukha, Y.; Watkins, M. B.; Redington, J. M.; Hopkins, J. B.; Dastvan, R.; Pozzi, N.; Korolev, S.

10.1101/2023.06.01.543259 — biophysics — Posted on 2023-06-05

3882 A guide to computational cotranscriptional folding featuring the SRP RNA

Badelt, S.; Lorenz, R.

10.1101/2023.06.01.543211 — bioinformatics — Posted on 2023-06-05

3883 SPRI: Structure-Based Pathogenicity Relationship Identifier for Predicting Effects of Single Missense Variants and Discovery of Higher-Order Cancer Susceptibility Clusters of Mutations

Wang, B.; Lei, X.; Tian, W.; Perez-Rathke, A.; Tseng, Y.-Y.; Liang, J.

10.1101/2022.09.27.508720 — bioinformatics — Posted on 2023-06-05

3884 A novel monocarboxylate transporter involved in 3-hydroxykynurenine transport for ommochrome coloration

Uchiyama, H.; Takasu, Y.; Moriyama, M.; Yoshitake, K.; Uchiyama, H.; Iizuka, T.; Uchino, K.; Okude, G.; Banno, Y.; Kuwazaki, S.; Yamamoto, K.; Yajima, S.; Hideki, S.; Tamura, T.; Futahashi, R.; Osanai-Futahashi, M.

10.1101/2023.06.01.543243 — genetics — Posted on 2023-06-05

3885 pi_tailtrack: A compact, inexpensive, and open-source behaviour-tracking system for head-restrained zebrafish

Randlett, O.

10.1101/2023.06.01.543206 — neuroscience — Posted on 2023-06-05

3886 Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky

Franke, K.; Cai, C.; Ponder, K.; Fu, J.; Sokoloski, S.; Berens, P.; Tolias, A. S.

10.1101/2023.06.01.543054 — neuroscience — Posted on 2023-06-05

3887 Obstructive Sleep Apnea Improves with Non-invasive Hypoglossal Nerve Stimulation using Temporal Interference

MISSEY, F.; Ejneby, M. S.; Ngom, I.; Donahue, M. J.; Trajlinek, J.; ACERBO, E.; Botzanowski, B.; Cassara, A.; Neufeld, E.; Glowacki, E. D.; Shangold, L.; Hanes, W. M.; Williamson, A.

10.1101/2023.04.06.535917 — neuroscience — Posted on 2023-06-05

3888 Stress- and phospholipid signalling responses in Arabidopsis PLC4-KO and -overexpression lines under salt- and osmotic stress

Hooren, M. v.; Darwish, E.; Munnik, T. v.

10.1101/2023.06.02.543366 — plant biology — Posted on 2023-06-05

3889 Identification of differentially expressed genes and enriched pathways in inflammatory bowel disease using bioinformatics and next generation sequencing data analysis

Vastrad, B.; Vastrad, C. M.

10.1101/2023.06.01.543204 — bioinformatics — Posted on 2023-06-05

3890 Revealing the Organ-Specific Expression of SPTBN1 using Single-Cell RNA Sequencing Analysis

Jung, J.; Wu, Q.

10.1101/2023.06.01.543198 — bioinformatics — Posted on 2023-06-05

3891 IPEV: Identification of Prokaryotic and Eukaryotic Virus-derived sequences in virome using deep learning

Yin, H.; Wu, S.; Tan, J.; Guo, Q.; Li, M.; Jiang, X.; Zhu, H.

10.1101/2023.05.28.541705 — bioinformatics — Posted on 2023-06-05

3892 scATAnno: Automated Cell Type Annotation for single-cell ATAC-seq Data

Jiang, Y.; Hu, Z.; Jiang, J.; Zhu, A.; Zhang, Y.; Lynch, A. W.; Xie, Y.; Li, R.; Zhou, N.; Meyer, C. A.; Cejas, P.; Brown, M.; Long, H. W.; Qiu, X.

10.1101/2023.06.01.543296 — bioinformatics — Posted on 2023-06-05

3893 Changes in Seasonal Footwear Elicited Alterations in Gait Kinematics but Not Stability

Garrah, S. N.; Best, A. N.; Wu, A. R.

10.1101/2023.05.18.541138 — bioengineering — Posted on 2023-06-05

3894 Catalytic activity of the Bin3/MEPCE methyltransferase domain is dispensable for 7SK snRNP function in Drosophila melanogaster

Palumbo, R. J.; Hanes, S. D.

10.1101/2023.06.01.543302 — genetics — Posted on 2023-06-05

3895 Catalytic activity of the Bin3/MEPCE methyltransferase domain is dispensable for 7SK snRNP function in Drosophila melanogaster

Palumbo, R. J.; Hanes, S. D.

10.1101/2023.06.01.543302 — genetics — Posted on 2023-06-05

3896 241,000 to 335,000 Years Old Rock Engravings Made by Homo naledi in the Rising Star Cave system, South Africa.

Berger, L. R.; Hawks, J.; Fuentes, A.; van Rooyen, D.; Tsikoane, M.; Ramalepa, M.; Nkwe, S.; Molopyane, K.

10.1101/2023.06.01.543133 — evolutionary biology — Posted on 2023-06-05

3897 Dynamics of bacterial recombination in the human gut microbiome

Liu, Z.; Good, B. H.

10.1101/2022.08.24.505183 — evolutionary biology — Posted on 2023-06-05

3898 Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis

Guicharnaud, C.; Groussier, G.; Beranger, E.; Lamy, L.; Vercken, E.; Dahirel, M.

10.1101/2023.01.24.525360 — ecology — Posted on 2023-06-05

3899 A Deep Learning Approach for Mental Health Quality Prediction Using Functional Network Connectivity and Assessment Data

Ajith, M.; Aycock, D. M.; Tone, E. B.; Liu, J.; Misiura, M. B.; Ellis, R.; King, T. Z.; Dotson, V. M.; Calhoun, V.

10.1101/2023.06.01.543257 — neuroscience — Posted on 2023-06-05

3900 Octopamine integrates the status of internal energy supply into the formation of food-related memories

Berger, M.; Auweiler, K.; Tegtmeier, M.; Dorn, K.; El Khadrawe, T.; Scholz, H.

10.1101/2023.06.01.543187 — neuroscience — Posted on 2023-06-05

3901 Random noise promotes slow heterogeneous synaptic dynamics important for robust working memory computation

Rungratsameetaweemana, N.; Kim, R.; Chotibut, T.; Sejnowski, T.

10.1101/2022.10.14.512301 — neuroscience — Posted on 2023-06-05

3902 Differential encoding of temporal context and expectation under representational drift across hierarchically connected areas

Wyrick, D. G.; Cain, N.; Larsen, R. S.; Lecoq, J. A.; Valley, M.; Ahmed, R.; Bowlus, J.; Boyer, G.; Caldejon, S.; Casal, L.; Chvilicek, M.; Departee, M.; Groblewski, P.; Huang, C.; Johnson, K.; Kato, I.; Larkin, J. D.; Lee, E.; Liang, E.; Luviano, J.; Mace, K.; Nayan, C.; Nguyen, T.; Reding, M.; Seid, S.; Sevigny, J.; Stoecklin, M.; Williford, A.; Choi, H.; Garrett, M. E.; Mazzucato, L.

10.1101/2023.06.02.543483 — neuroscience — Posted on 2023-06-05

3903 Mutator transposon insertions within maize genes often provide a novel outward reading promoter

Ellison, E. E.; Zhou, P.; Hermanson, P. J.; Read, A.; Chu, Y.-H.; Hirsch, C. N.; Grotewold, E.; Springer, N. M.

10.1101/2023.06.05.543741 — plant biology — Posted on 2023-06-05

3904 GIMLET: A Unified Graph-Text Model for Instruction-Based Molecule Zero-Shot Learning

Zhao, H.; Liu, S.; Ma, C.; Xu, H.; Fu, J.; Deng, Z.-H.; Kong, L.; Liu, Q.

10.1101/2023.05.30.542904 — bioinformatics — Posted on 2023-06-05

3905 DIVE: a reference-free statistical approach to diversity-generating and mobile genetic element discovery

Abante, J.; Wang, P. L.; Salzman, J.

10.1101/2022.06.13.495703 — bioinformatics — Posted on 2023-06-05

3906 kmindex and ORA: indexing and real-time user-friendly queries in terabytes-sized complex genomic datasets

Lemane, T.; Lezzoche, N.; Lecubin, J.; Pelletier, E.; Lescot, M.; Chikhi, R.; Peterlongo, P.

10.1101/2023.05.31.543043 — bioinformatics — Posted on 2023-06-05

3907 Proteostatic tuning underpins the evolution of novel multicellular traits

Montrose, K.; Lac, D. T.; Burnetti, A. J.; Tong, K.; Bozdag, G. O.; Hukkanen, M.; Ratcliff, W. C.; Saarikangas, J.

10.1101/2023.05.31.543183 — evolutionary biology — Posted on 2023-06-05

3908 Isolation by environment is more important than isolation by distance along a tropical gradient in direct developing frogs

Percino-Daniel, R.; Jones, K.; Maigret, T. A.; Weisrock, D. W.; Pinero, D.

10.1101/2023.06.01.543162 — evolutionary biology — Posted on 2023-06-05

3909 Fast and flexible Bayesian Jolly Seber models and application to populations with transients

Saracco, J. F.; Yackulic, C. B.

10.1101/2023.05.25.542303 — ecology — Posted on 2023-06-05

3910 BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation

Picas, L.; Comunale, F.; Andre-Arpin, C.; Bousquet, H.; Tsai, F.-C.; Rico, F.; Maiuri, P.; Pernier, J.; Bodin, S.; Nicot, A.-S.; Laporte, J.; Bassereau, P.; Goud, B.; Gauthier-Rouviere, C.; Miserey, S.

10.1101/2022.03.21.485158 — cell biology — Posted on 2023-06-05

3911 Aberrant functional brain network organization is associated with relapse during 1-year follow-up in alcohol-dependent patients

Bohmer, J.; Reinhardt, P.; Garbusow, M.; Marxen, M.; Smolka, M. N.; Zimmermann, U. S.; Heinz, A.; Bzdok, D.; Friedel, E.; Kruschwitz, J. D.; Walter, H.

10.1101/2023.06.01.543210 — neuroscience — Posted on 2023-06-05

3912 Calretinin-expressing islet cells: a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord

Davis, O. C.; Dickie, A. C.; Mustapa, M. B.; Boyle, K. A.; Browne, T. J.; Gradwell, M. A.; Smith, K. M.; Polgar, E.; Bell, A. M.; Kokai, E.; Watanabe, M.; Wildner, H.; Zeilhofer, H. U.; Ginty, D. D.; Callister, R. J.; Graham, B. A.; Todd, A. J.; Hughes, D. I.

10.1101/2023.06.01.543241 — neuroscience — Posted on 2023-06-05

3913 Single-Nucleus RNA Sequencing of Developing and Mature Superior Colliculus Identifies Neuronal Diversity and Candidate Mediators of Circuit Assembly

Ayupe, A. C.; Choi, J. S.; Beckedorff, F.; Catanuto, P.; Mccartan, R.; Levay, K.; Park, K. K.

10.1101/2023.02.01.526254 — neuroscience — Posted on 2023-06-05

3914 Judging the difficulty of perceptual decisions

Löffler, A.; Zylberberg, A.; N. Shadlen, M.; Wolpert, D. M.

10.1101/2023.02.13.528254 — neuroscience — Posted on 2023-06-05

3915 Genetic basis of historical pea mutants that hyper-accumulate iron

Harrington, S. A.; Franceschetti, M.; Balk, J.

10.1101/2023.06.05.543728 — plant biology — Posted on 2023-06-05

3916 Stabilisation of soil organic matter with rock dust partially counteracted by plants

Buss, W.; Hasemer, H.; Ferguson, S.; Borevitz, J. O.

10.1101/2023.06.02.543347 — plant biology — Posted on 2023-06-05

3917 MR-DNA: Flexible 5mC-Methylation-Site Recognition in DNA Sequences using Token Classification

Zeng, W.; Huson, D.

10.1101/2023.06.01.543218 — bioinformatics — Posted on 2023-06-05

3918 The 3D modules of enzyme catalysis: deconstructing active sites into distinct functional entities

Riziotis, I. G.; Ribeiro, A. J. M.; Borkakoti, N.; Thornton, J. M.

10.1101/2023.06.01.543252 — bioinformatics — Posted on 2023-06-05

3919 Maintenance of cooperation in a yeast population in a public-good driven system.

Raj, N.; Saini, S.

10.1101/2023.06.01.543253 — evolutionary biology — Posted on 2023-06-05

3920 Diversity and evolutionary growth of biomineralized columns in early Cambrian phosphatic-shelled brachiopods

Zhang, Z.; Zhang, Z.; Holmer, L. E.; Topper, T. P.; Pan, B.; Li, G.

10.1101/2023.06.01.543202 — evolutionary biology — Posted on 2023-06-05

3921 A novel small molecule PKC epsilon inhibitor reduces hyperalgesia induced by paclitaxel or opioid withdrawal

Gregory-Flores, A.; Magayewski Bonet, I. J.; Desaivre, S.; Levine, J. D.; McHardy, S. F.; de Kraker, H.; Russell, N.; Fleischer, C.; Messing, R.; Marinelli, M.

10.1101/2023.06.01.543325 — neuroscience — Posted on 2023-06-05

3922 Mesostriatal dopamine is sensitive to specific cue-reward contingencies

Garr, E.; Cheng, Y.; Jeong, H.; Brooke, S.; Castell, L.; Bal, A.; Magnard, R.; Namboodiri, V. M. K.; Janak, P. H.

10.1101/2023.06.05.543690 — neuroscience — Posted on 2023-06-05

3923 Study of auxin metabolism using stable isotope labeling and LCMS; evidence for in planta auxin decarboxylation pathway.

Dobrev, P. I.; Filepova, R.; Lacek, J.; Vondrakova, Z.; Muller, K.; Marsik, P.; Drasarova, L.; Talacko, P.; Hosek, P.; Petrasek, J.

10.1101/2023.06.02.543384 — plant biology — Posted on 2023-06-05

3924 LORA, Lipid Over-Representation Analysis based on structural information

Vondrackova, M.; Kopczynski, D.; Hoffmann, N.; Kuda, O.

10.1101/2023.06.02.543363 — bioinformatics — Posted on 2023-06-05

3925 Utilizing Aggregated Molecular Phenotype (AMP) Scores to Visualize Simultaneous Molecular Changes in Mass Spectrometry Imaging Data

Chappel, J. R.; King, M. E.; Fleming, J.; Eberlin, L. S.; Reif, D. M.; Baker, E.

10.1101/2023.06.01.543306 — bioinformatics — Posted on 2023-06-05

3926 Quantifying the impact of sample, instrument, and data processing on biological signatures detected with Raman spectroscopy

Wiemann, J.; Heck, P. R.

10.1101/2023.06.01.543279 — evolutionary biology — Posted on 2023-06-05

3927 Burials and engravings in a small-brained hominin, Homo naledi, from the late Pleistocene: contexts and evolutionary implications

Fuentes, A.; Kissel, M.; Spikins, P.; Molopyane, K.; Hawks, J.; Berger, L. R.

10.1101/2023.06.01.543135 — evolutionary biology — Posted on 2023-06-05

3928 Auditory steady-state responses: multiplexed amplitude modulation frequencies to reduce recording time

Sonck, R.; Vanthornhout, J.; Bonin, E.; Francart, T.

10.1101/2023.06.01.543200 — neuroscience — Posted on 2023-06-05

3929 BrainBeats: an open-source EEGLAB plugin to jointly analyze EEG and cardiovascular (ECG/PPG) signals

Cannard, C.; Wahbeh, H.; Delorme, A.

10.1101/2023.06.01.543272 — neuroscience — Posted on 2023-06-05

3930 Ectopic Expression of Distinct PLC Genes Identifies 'Compactness' as Novel Architectural Shoot Strategy to Cope with Drought Stress

Hooren, M. v.; van Wijk, R.; Vaseva, I.; Van Der Straeten, D.; Haring, M.; Munnik, T.

10.1101/2023.06.02.543233 — plant biology — Posted on 2023-06-05

3931 Mapping the Arabidopsis thaliana proteome in PeptideAtlas and the nature of the unobserved (dark) proteome; strategies towards a complete proteome

van Wijk, K. J.; Leppert, T.; Sun, Z.; Kearly, A.; Li, M.; Mendoza, L.; Guzchenko, I.; debley, E.; Sauermann, G.; Routray, P.; Malhotra, S.; Nelson, A. D. L.; Sun, Q.; Deutsch, E. W.

10.1101/2023.06.01.543322 — plant biology — Posted on 2023-06-05

3932 Can Quantum Chemistry Improve the understanding of Protein-Ligand Interactions? Implications for Structure Based Drug Discovery

Menezes, F.; Froehlich, T.; Popowicz, G. M.

10.1101/2023.06.01.543295 — bioinformatics — Posted on 2023-06-05

3933 Efficient Analysis of Proteome-wide FPOP Data by FragPipe

Ramirez, C. R.; Espino, J. A.; Jones, L. M.; Polasky, D. A.; Nesvizhskii, A. I.

10.1101/2023.06.01.543263 — bioinformatics — Posted on 2023-06-05

3934 Genetic and functional diversity help explain pathogenic, weakly pathogenic, and commensal lifestyles in the genus Xanthomonas

Pena, M. M.; Bhandari, R.; Bowers, R. M.; Weis, K.; Newberry, E.; Wagner, N.; Pupko, T.; Jones, J. B.; Woyke, T.; Vinatzer, B. A.; Jacques, M.-A.; Potnis, N.

10.1101/2023.05.31.543148 — ecology — Posted on 2023-06-05

3935 Influence of traffic and weather on carcass persistence time of small wildlife on roads

Benard, A.; Bonenfant, C.; Lengagne, T.

10.1101/2023.06.01.543226 — ecology — Posted on 2023-06-05

3936 Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function

Bowles, K. R.; Pugh, D. A.; Pedicone, C.; Oja, L.-M.; Weitzman, S. A.; Liu, Y.; Chen, J. L.; Disney, M. D.; Goate, A. M.

10.1101/2023.06.02.543224 — neuroscience — Posted on 2023-06-05

3937 5-MeO-DMT induces sleep-like LFP spectral signatures in the hippocampus and prefrontal cortex of awake rats

Souza, A. d. C.; Souza, B. d. C.; Franca, A. S.; Moradi, M.; Souza, N. d. C.; Leao, K. E.; Tort, A. B.; Leao, R.; Lopes-dos-Santos, V.; Ribeiro, S.

10.1101/2023.06.01.543303 — neuroscience — Posted on 2023-06-05

3938 Dynamic phytomeric growth contributes to local adaptation in barley

Huang, Y.; Maurer, A.; Giehl, R. F. H.; Zhao, S.; Golan, G.; Thirulogachandar, V.; Li, G.; Zhao, Y.; Trautewig, C.; Himmelbach, A.; Boerner, A.; Jayakodi, M.; Stein, N.; Mascher, M.; Pillen, K.; Schnurbusch, T.

10.1101/2023.06.02.543309 — plant biology — Posted on 2023-06-05

3939 Evidence for deliberate burial of the dead by Homo naledi

Berger, L. R.; Makhubela, T.; Molopyane, K.; Kruger, A.; Randolph-Quinney, P.; Elliott, M.; Peixotto, B.; Fuentes, A.; Tafforeau, P.; Beyrand, V.; Dollman, K.; Jinnah, Z.; Brewer Gillham, A.; Broad, K.; Brophy, J.; Chinamatira, G.; Dirks, P.; Feuerriegel, E.; Gurtov, A.; Hlophe, N.; Hunter, L.; Hunte, R.; Jakata, K.; Jaskolski, C.; Morris, H.; Pryor, E.; Ramaphela, M.; Roberts, E.; Smilg, J.; Tsikoane, M.; Tucker, S.; van Rooyen, D.; Warren, K.; Wren, C.; Kissel, M.; Spikins, P.; Hawks, J.

10.1101/2023.06.01.543127 — paleontology — Posted on 2023-06-05

3940 Assessing the Predictive Ability of Computational Epitope Prediction Methods on Fel d 1 Allergen

Lee, J. K.; Ko, S.; Ha, K.; Choi, Y.

10.1101/2023.06.01.543222 — bioinformatics — Posted on 2023-06-05

3941 Molecular Dynamics and Water site bias docking method allows the identification of key amino acids in the Carbohydrate Recognition Domain of a viral protein

Gamarra, M. D.; Dieterle, M. E.; Blanco Capurro, J. I.; Radusky, L.; Piuri, M.; Modenutti, C. P.

10.1101/2023.06.01.543333 — bioinformatics — Posted on 2023-06-05

3942 Engineering ligand stabilized aquaporin reporters for magnetic resonance imaging

Yun, J.; Baldini, L.; Huang, Y.; Li, E.; Li, H.; Chacko, A. N.; Miller, A. D. C.; Wan, J.; Mukherjee, A.

10.1101/2023.06.02.543364 — bioengineering — Posted on 2023-06-05

3943 Environmental life cycle assessment of recombinant growth factor production for cultivated meat applications

Trinidad, K. R.; Ashizawa, R.; Nikkhah, A.; Semper, C.; Casolaro, C.; Kaplan, D.; Savchenko, A.; Tichenor-Blackstone, N.

10.1101/2023.06.01.543245 — ecology — Posted on 2023-06-05

3944 New resources for environmental genomics in the wild Mediterranean grass B. distachyon

Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.

10.1101/2023.06.01.543285 — ecology — Posted on 2023-06-05

3945 Gestational exposure to bisphenol S induces microvesicular steatosis by promoting lipogenesis and inflammation in male rat offspring

Molangiri, A.; Varma, S.; Hridayanka, K. S. N.; Srinivas, M.; Kona, S. R.; Ibrahim, A.; Duttaroy, A. K.; Basak, S.

10.1101/2023.06.01.543354 — developmental biology — Posted on 2023-06-05

3946 Unveiling the intricacies: Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder

Miyahara, K.; Tatehana, M.; Kikkawa, T.; Osumi, N.

10.1101/2023.06.01.543326 — developmental biology — Posted on 2023-06-05

3947 Macrophages modulate fibrosis during newt lens regeneration

Tsissios, G.; Sallese, A.; Perez-Estrada, J. R.; Tangeman, J.; Chen, W.; Smucker, B.; Ratvasky, S.; Grajales-Esquivel, E.; Martinez, A.; Visser, K. J.; Araus, A. J.; Wang, H.; Simon, A.; Yun, M.; Del Rio-Tsonis, K.

10.1101/2023.06.04.543633 — developmental biology — Posted on 2023-06-05

3948 Recording morphogen signals reveals origins of gastruloid symmetry breaking

McNamara, H. M.; Solley, S. C.; Adamson, B.; Chan, M. M.; Toettcher, J. E.

10.1101/2023.06.02.543474 — developmental biology — Posted on 2023-06-05

3949 Endodermal cells use contact inhibition of locomotion to achieve uniform cell dispersal during zebrafish gastrulation

LaBelle, J.; Wyatt, T.; Woo, S.

10.1101/2023.06.01.543209 — developmental biology — Posted on 2023-06-05

3950 Discovery of a new craniofacial gene influencing adaptive phenotypes in a non-model pupfish radiation

Palominos, M. F.; Muhl, V.; Richards, E. J.; Martin, C. H.

10.1101/2023.06.02.543513 — developmental biology — Posted on 2023-06-05

3951 The mechanical force with the physiological movement works as a biological cue in tendon development during the postnatal phase in mice

Usami, Y.; Kokubun, T.

10.1101/2023.06.02.543346 — developmental biology — Posted on 2023-06-05

3952 The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neurosecretory protein in the Drosophila CNS.

Sukumar, S. K.; Antonydhason, V.; Molander, L.; Sandakly, J.; Umapathy, G.; Mendoza-Garcia, P.; Masudi, T.; Schlosser, A.; Nassel, D. R.; Wegener, C.; Shirinian, M.; Palmer, R.

10.1101/2023.06.02.543395 — developmental biology — Posted on 2023-06-05

3953 The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis

Tejeda Munoz, N.; Azbazdar, Y.; Monka, J.; Binder, G.; Ayala, R.; Dayrit, A.; O'Brien, N.; De Robertis, E. M.

10.1101/2023.06.02.543509 — developmental biology — Posted on 2023-06-05

3954 Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution

Ishida, T.; Heck, A. M.; Varnum-Finney, B.; Dozono, S.; Nourigat-McKay, C.; Kraskouskas, K.; Wellington, R.; Waltner, O.; Root, C.; Jackson, D. L.; Delaney, C.; Rafii, S.; Bernstein, I. D.; Trapnell, C.; Hadland, B.

10.1101/2023.06.01.543314 — developmental biology — Posted on 2023-06-05

3955 Compartmentalization and synergy of osteoblasts drive bone formation in the regenerating fin

Cudak, N.; Lopez-Delgado, A. C.; Rost, F.; Kurth, T.; Lesche, M.; Reinhardt, S.; Dahl, A.; Rulands, S.; Knopf, F.

10.1101/2023.06.04.543617 — developmental biology — Posted on 2023-06-05

3956 Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.

Franco-Enzastiga, U.; Natarajan, K.; David, E. T.; Patel, K. J.; Ravirala, A.; Price, T. J.

10.1101/2023.06.03.543579 — neuroscience — Posted on 2023-06-05

3957 Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states

Varga, Z. K.; Pejtsik, D.; Toth, M.; Balogh, Z.; Aliczki, M.; Szente, L.; Balla, G. Y.; Kontra, L.; Eckert, Z.; Zsolt, B.; Mikics, E.

10.1101/2023.06.01.543235 — neuroscience — Posted on 2023-06-05

3958 Offline Two-dimensional Liquid Chromatography-Mass Spectrometry for Deep Annotation of the Fecal Metabolome

Anderson, B. G.; Raskind, A.; Theriot, C. M.; Kennedy, R. T.; Evans, C. R.

10.1101/2023.05.31.543178 — systems biology — Posted on 2023-06-05

3959 Initiation of B-type starch granules in wheat endosperm requires the plastidial α-glucan phosphorylase PHS1

Kamble, N. U.; Makhamadjonov, F.; Fahy, B.; Martins, C.; Saalbach, G.; Seung, D.

10.1101/2023.06.01.543270 — plant biology — Posted on 2023-06-05

3960 Harnessing deep learning to analyze cryptic morphological variability of Marchantia polymorpha

Tomizawa, Y.; Minamino, N.; Shimokawa, E.; Kawamura, S.; Komatsu, A.; Hiwatashi, T.; Nishihama, R.; Ueda, T.; Kohchi, T.; Kondo, Y.

10.1101/2023.05.31.543177 — plant biology — Posted on 2023-06-05

3961 Some like it hot: adaptation to the urban heat island in common dandelion.

Woudstra, Y.; Kraaiveld, R.; Jorritsma, A.; Vijverberg, K.; Ivanovic, S.; Erkens, R.; Huber, H.; Gravendeel, B.; Verhoeven, K. J.

10.1101/2023.06.01.543268 — plant biology — Posted on 2023-06-05

3962 Energetical equivalence between air resistance and gradients in running

Leclerc, M.

10.1101/2023.06.01.543316 — physiology — Posted on 2023-06-05

3963 The G protein biased serotonin 5-HT 2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice

Pogorelov, V. M.; Rodriguiz, R. M.; Roth, B. L.; Wetsel, W. C.

10.1101/2023.06.01.543310 — pharmacology and toxicology — Posted on 2023-06-05

3964 Learning Peptide Properties with Positive Examples Only

Ansari, M.; White, A. D.

10.1101/2023.06.01.543289 — bioinformatics — Posted on 2023-06-05

3965 scATAnno: Automated Cell Type Annotation for single-cell ATAC-seq Data

Jiang, Y.; Hu, Z.; Jiang, J.; Zhu, A.; Zhang, Y.; Lynch, A. W.; Xie, Y.; Li, R.; Cejas, P.; Meyer, C. A.; Qiu, X.; Brown, M.; Long, H. W.; Zhou, N.

10.1101/2023.06.01.543296 — bioinformatics — Posted on 2023-06-05

3966 Updating TCGA glioma classification through integration of molecular profiling data following the 2016 and 2021 WHO guidelines

Medonca, M. L.; Coletti, R.; Goncalves, C. S.; Martins, E. P.; Costa, B. M.; Vinga, S.; Lopes, M. B.

10.1101/2023.02.19.529134 — bioinformatics — Posted on 2023-06-05

3967 A population-averaged structural connectomic brain atlas of 422 HCP-Aging subjects

Xiao, Y.; Lau, J. C.; Peters, T. M.; Khan, A. R.

10.1101/2023.06.01.543240 — bioengineering — Posted on 2023-06-05

3968 A semiconductor 96-microplate platform for real-time impedance-based high-throughput screening

Chitale, S.; Wu, W.; Mukherjee, A.; Lannon, H.; Suresh, P.; Nag, I.; Ambrosi, C.; Gertner, R. A.; Melo, H.; Powers, B.; Wilkins, H.; Hinton, H.; Cheah, M.; Boynton, Z.; Alexeyev, A.; Sword, D.; Basan, M.; Park, H.; Ham, D.; Abbott, J.

10.1101/2023.06.01.543281 — bioengineering — Posted on 2023-06-05

3969 A Drosophila model of chemotherapy-related cognitive impairment

Torre, M.; Bukhari, H.; Nithianandam, V.; Zanella, C. A.; Mata, D. A.; Feany, M. B.

10.1101/2023.06.01.543297 — animal behavior and cognition — Posted on 2023-06-05

3970 Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

Stewart, H.; Grinfeld, D.; Giannakopulos, A.; Petzoldt, J.; Shanley, T.; Garland, M.; Denisov, E.; Peterson, A.; Damoc, E.; Zeller, M.; Arrey, T.; Pashkova, A.; Renuse, S.; Hakimi, A.; Kuehn, A.; Biel, M.; Kreutzmann, A.; Hagedorn, B.; Colonius, I.; Schuetz, A.; Stefes, A.; Dwivedi, A.; Mourad, D.; Hoek, M.; Reitemeier, B.; Cochems, P.; Kholomeev, A.; Ostermann, R.; Quiring, G.; Ochmann, M.; Moehring, S.; Wagner, A.; Petker, A.; Kanngiesser, S.; Wiedemeyer, M.; Balschun, W.; Hermanson, D.; Zabrouskov, V.; Makarov, A.; Hock, C.

10.1101/2023.06.02.543408 — cell biology — Posted on 2023-06-05

3971 Temporal transcriptome analysis of the endothelial response to tumour necrosis factor

Struck, E.; Belova, T.; Hsieh, P.-H.; Odeberg, J.; Kuijjer, M. L.; Dusart, P.; Butler, L.

10.1101/2023.06.04.543378 — cell biology — Posted on 2023-06-05

3972 Interplay of CaHVA and Ca2+-activated K+ channels affecting firing rate in perineuronal net disruption

Hanssen, K. O.; Ness, T. V.; Halnes, G.

10.1101/2023.06.05.543694 — neuroscience — Posted on 2023-06-05

3973 Decoding Arbitrary and Informed Decisions from Intracranial Recordings in Humans

Marras, L.; Verwoert, M.; Ottenhoff, M. C.; Goulis, S.; van Dijk, J. P.; Tousseyn, S.; Wagner, L.; Colon, A. J.; Kubben, P. L.; Janssen, M. L.; Herff, S. A.; Herff, C.

10.1101/2023.06.01.543070 — neuroscience — Posted on 2023-06-05

3974 DGRPool: A web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits

Gardeux, V.; Bevers, R. P.; David, F. P. A.; Rosschaert, E.; Rochepeau, R.; Deplancke, B.

10.1101/2023.06.01.543194 — systems biology — Posted on 2023-06-05

3975 Species-Specific Responses Drive Browsing Impacts on Physiological and Functional Traits in Coast Live Oak (Quercus agrifolia) and Bay Laurel (Umbellularia californica)

Leonard, H. E.; Ciambrone, M.; Pittermann, J.

10.1101/2023.06.01.543299 — plant biology — Posted on 2023-06-05

3976 A novel method for tracking nitrogen kinetics in vivo and ex vivo using radioactive nitrogen-13 gas and Positron Emission Tomography

Ashworth, E.; Ogawa, R.; Vera, D. R.; Lindholm, P.

10.1101/2023.06.01.543280 — physiology — Posted on 2023-06-05

3977 PICNIC identifies condensate-forming proteins across organisms

Hadarovich, A.; Singh, H. R.; Ghosh, S.; Rostam, N.; Hyman, A. A.; Toth-Petroczy, A.

10.1101/2023.06.01.543229 — bioinformatics — Posted on 2023-06-05

3978 Predicting condensate formation of protein and RNA under various environmental conditions

Chin, K. Y.; Ishida, S.; Terayama, K.

10.1101/2023.06.01.543215 — bioinformatics — Posted on 2023-06-05

3979 Tau protein modulates an epigenetic mechanism of cellular senescence

Magrin, C.; Sola, M.; Piovesana, E.; Bolis, M.; Rinaldi, A.; Papin, S.; Paganetti, P.

10.1101/2023.06.05.543662 — cell biology — Posted on 2023-06-05

3980 Modeling of lung-liver interaction during infection in a human microfluidic organ-on-a-chip

Reinhold, S.; Herr, C.; Yao, Y.; Pourrostami, M.; Ritzmann, F.; Lehr, T.; Selzer, D.; Kohl, Y. L.; Yildiz, D.; Slevogt, H.; Beisswenger, C.; Bals, R.

10.1101/2023.06.01.543192 — cell biology — Posted on 2023-06-05

3981 Machine Learning Classification of Alzheimer's Disease Pathology Reveals Diffuse Amyloid as a Major Predictor of Cognitive Impairment in Human Hippocampal Subregions

Stephen, T.-L.; Korobkova, L.; Breningstall, B.; Nguyen, K.; Mehta, S.; Pachicano, M.; Jones, K.; Hawes, D.; Cabeen, R. P.; Bienkowski, M.

10.1101/2023.05.31.543117 — neuroscience — Posted on 2023-06-05

3982 Attention Modulates Human Visual Responses to Objects by Tuning Sharpening

Doostani, N.; Hossein-Zadeh, G.-A.; Cichy, R. M.; Vaziri-Pashkam, M.

10.1101/2023.06.01.543205 — neuroscience — Posted on 2023-06-05

3983 Insulin-like Growth Factor-1 Supplementation Promotes Kidney Development and Alleviate Renal Inflammation in Preterm Pigs

Zhong, J.; Thymann, T.; Sangild, P. T.; Nguyen, D. N.; Muk, T.

10.1101/2023.06.01.543191 — physiology — Posted on 2023-06-05

3984 Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak-Keller-Segel chemotaxis model

Phan, T. V.; Mattingly, H. H.; Vo, L.; Marvin, J. S.; Looger, L. L.; Emonet, T.

10.1101/2023.06.01.543315 — biophysics — Posted on 2023-06-05

3985 Spatial redundancy transformer for self-supervised fluorescence image denoising

Li, X.; Hu, X.; Chen, X.; Fan, J.; Zhao, Z.; Wu, J.; Wang, H.; Dai, Q.

10.1101/2023.06.01.543361 — biophysics — Posted on 2023-06-05

3986 Identification of non-conventional small molecule degraders and stabilizers of squalene synthase

Hoock, J. G. F.; Rossetti, C.; Bilgin, M.; Depta, L.; Enemark-Rasmussen, K.; Christianson, J. C.; Laraia, L.

10.1101/2023.06.02.543387 — cell biology — Posted on 2023-06-05

3987 A Novel Angiogenesis Role of GLP-1(32-36) to Rescue Diabetic Ischemic Lower Limbs via GLP-1R-Dependent Glycolysis

Zheng, C.; Zhang, Y.; Wang, S.; Zhou, Q.; Hu, Y.; Xie, Y.; Fang, W.; Yang, C.; Wang, Z.; Ye, S.; Wang, X.

10.1101/2023.06.01.543344 — cell biology — Posted on 2023-06-05

3988 Functional ultrasound imaging of stroke in awake rats

Brunner, C.; Montaldo, G.; Urban, A.

10.1101/2023.05.31.543179 — neuroscience — Posted on 2023-06-05

3989 Intact reinforcement learning in healthy ageing

Lin, W.-H.; Clarke, A.; Pilz, K. S.; Herzog, M. H.; Kunchulia, M.

10.1101/2023.05.25.542104 — neuroscience — Posted on 2023-06-05

3990 A new pipeline SPICE identifies novel JUN-IKZF1 composite elements

Li, P.; Pulugulla, S. H.; Das, S.; Oh, J.; Spolski, R.; Lin, J.-X.; Leonard, W. J.

10.1101/2023.05.31.543110 — systems biology — Posted on 2023-06-05

3991 Stable mammalian serum albumins designed for bacterial expression

Khersonsky, O.; Goldsmith, M.; Zaretsky, I.; Hamer-Rogotner, S.; Dym, O.; Unger, T.; Yona, M.; Fridmann-Sirkis, Y.; Fleishman, S. J.

10.1101/2023.03.28.534334 — biochemistry — Posted on 2023-06-05

3992 Evolutionary determinants of reproductive seasonality: a theoretical approach

Burtschell, L.; Dezeure, J.; Huchard, E.; Godelle, B.

10.1101/2022.08.22.504761 — ecology — Posted on 2023-06-05

3993 Mind of a dauer: Comparative connectomics reveals developmental plasticity

Yim, H.; Choe, D. T.; Bae, J. A.; Kang, H.-M.; Nguyen, K. C. Q.; Choi, M.-k.; Ahn, S.; Bahn, S.-k.; Yang, H.; Hall, D. H.; Kim, J. S.; Lee, J.

10.1101/2023.03.23.533915 — neuroscience — Posted on 2023-06-05

3994 Micelle-like clusters in phase-separated Nanog condensates: A molecular simulation study

Mizutani, A.; Tan, C.; Sugita, Y.; Takada, S.

10.1101/2023.05.18.541260 — biophysics — Posted on 2023-06-05

3995 dsRID: Editing-free in silico identification of dsRNA region using long-read RNA-seq data

Yamamoto, R.; Liu, Z.; Choundhury, M.; Xiao, X.

10.1101/2023.06.02.543466 — bioinformatics — Posted on 2023-06-05

3996 Multiple hosts, multiple impacts: the role of vertebrate host diversity in shaping mosquito life history and pathogen transmission

Vantaux, A.; Moiroux, N.; Dabire, K. R.; Cohuet, A.; Lefevre, T.

10.1101/2023.02.10.527988 — evolutionary biology — Posted on 2023-06-05

3997 But, what are the cells doing? Image Analysis pipeline to follow single cells in the zebrafish embryo

Rama, A. B.; Venzin, O. F.; Rohde, L.; Chiaruttini, N.; Oates, A. C.

10.1101/2023.06.01.543221 — developmental biology — Posted on 2023-06-05

3998 Single cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, ageing and disease

Kilfeather, P.; Khoo, J. H.; Wagner, K.; Liang, H.; Caiazza, M.-C.; An, Y.; Zhang, X.; Chen, X.; Connor-Robson, N.; Shang, Z.; Wade-Martins, R.

10.1101/2023.04.20.537553 — molecular biology — Posted on 2023-06-04

3999 Single-cell RNA sequencing reveals subset-specific functional reprogramming of CD4+ T-cells from PLHIV upon ex vivo HDAC inhibition and biomarkers of cells harbouring non-silent proviruses

Kazmierski, J.; Postmus, D.; Wyler, E.; Fadejeva, J.; Steijaert, T.; Fischer, C.; Jansen, J.; Koppe, U.; Gunsenheimer-Bartmeyer, B.; Meixenberger, K.; Vitcetz, S.; Sohn, M.; Loyal, L.; Thiel, A.; Sauer, S.; Bannert, N.; Landthaler, M.; GOFFINET, C.

10.1101/2020.05.04.075119 — microbiology — Posted on 2023-06-04

4000 The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk

Liang, Q.; Jiang, Y.; Shieh, A. W.; Zhou, D.; Chen, R.; Wang, F.; Xu, M.; Wang, X.; Pinto, D.; Wang, Y.; Cheng, L.; Vadukapuram, R.; Zhang, C.; Grennan, K.; Giase, G.; The PsychENCODE Consortium, ; White, K. P.; Peng, J.; Li, B.; Liu, C.; Chen, C.; Wang, S. H.

10.1101/2023.06.04.543603 — genetics — Posted on 2023-06-05

4001 Multi-scale Modeling and Experimental Data Enable Structural Models of the Escherichia Coli Peptidoglycan to be Constructed on the Whole-Cell Scale

Wehrspan, Z. J.; Elcock, A. H.

10.1101/2023.06.04.543634 — microbiology — Posted on 2023-06-04

4002 Investigating Alternative Models of Acute HIV infection

Mainou, E.; Ribeiro, R. M.; Conway, J. M.

10.1101/2023.06.04.543605 — microbiology — Posted on 2023-06-04

4003 Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation

Asai, R.; Prakash, V. N.; Sinha, S.; Prakash, M.; Mikawa, T.

10.1101/2023.05.26.542486 — developmental biology — Posted on 2023-06-04

4004 Human Rhinoviruses: a novel class of oncolytic virus

Burnett, W. J.; Cluff, A.; Reeves, M.; Parkman, G. L.; Hart, C.; Ramstead, A.; Holmen, S.; Williams, M. A.; VanBrocklin, M. W.

10.1101/2023.05.31.542867 — immunology — Posted on 2023-06-04

4005 Comprehensively defining cellular specializations for initiating parallel auditory pathways in the mouse cochlear nucleus

Jing, J.; Hu, M.; Ngodup, T.; Ma, Q.; Lau, S. N. N.; Ljungberg, C.; McGinley, M. J.; Trussell, L. O.; Jiang, X.

10.1101/2023.05.15.539065 — neuroscience — Posted on 2023-06-04

4006 Random noise promotes slow heterogeneous synaptic dynamics important for robust working memory computation

Rungratsameetaweemana, N.; Kim, R.; Chotibut, T.; Sejnowski, T.

10.1101/2022.10.14.512301 — neuroscience — Posted on 2023-06-04

4007 Probabilistic Coverage of the Frontal Aslant Tract in Young Adults: Insights into Individual Variability, Lateralization, and Language Functions

Linn, W.-J.; Barrios-Martinez, J.; Fernandes-Cabral, D.; Jacquesson, T.; Nunez, M.; Gomez, R.; Anania, Y.; Fernandez-Miranda, J.; Yeh, F.-C.

10.1101/2023.06.03.543491 — neuroscience — Posted on 2023-06-04

4008 Cell age drives asynchronous transcriptome aging

Yang, M.; Harrison, B.; Promislow, D. E.

10.1101/2023.05.31.543091 — systems biology — Posted on 2023-06-04

4009 A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer

Brown, B. A.; Myers, P. J.; Adair, S. J.; Pitarresi, J. R.; Sah-Teli, S. K.; Campbell, L. A.; Hart, W. S.; Barbeau, M.; Leong, K.; Seyler, N.; Kane, W.; Lee, K. E.; Stelow, E.; Jones, M.; Simon, M. C.; Koivunen, P.; Bauer, T. W.; Stanger, B. Z.; Lazzara, M. J.

10.1101/2022.10.19.512869 — cancer biology — Posted on 2023-06-04

4010 Opi1-mediated transcriptional modulation orchestrates genotoxic stress response in budding yeast

Panessa, G. M.; Tassoni-Tsuchida, E.; Pires, M. R.; Felix, R. R.; Jekabson, R.; de Souza-Pinto, N. C.; da Cunha, F. M.; Brandman, O.; Cussiol, J. R. R.

10.1101/2022.11.04.515212 — cell biology — Posted on 2023-06-04

4011 Graph Laplacian Spectrum of Structural Brain Networks is Subject-Specific, Repeatable but Highly Dependent on Graph Construction Scheme

Dimitriadis, S. I.; Messaritaki, E.; Jones, D.

10.1101/2023.05.31.543029 — neuroscience — Posted on 2023-06-04

4012 Short-term Hebbian learning can implementtransformer-like attention

Ellwood, I. T.

10.1101/2023.05.31.543109 — neuroscience — Posted on 2023-06-04

4013 Non-genetic differences underlie variability in proliferation among esophageal epithelial clones

Reyes Hueros, R. A.; Gier, R. A.; Shaffer, S. M.

10.1101/2023.05.31.543080 — systems biology — Posted on 2023-06-04

4014 Modulation of antigen discrimination by duration of immune contacts in a kinetic proofreading model of T cell activation with extreme statistics.

Morgan, J.; Lindsay, A.

10.1101/2023.05.30.542789 — systems biology — Posted on 2023-06-04

4015 Tropical butterflies lose central nervous system function in the cold from a spreading depolarization event

Andersen, M. K.; Willot, Q.; MacMillan, H. A.

10.1101/2023.05.31.543057 — physiology — Posted on 2023-06-04

4016 Ribosome clustering and surface layer reorganization in the microsporidian host-invasion apparatus.

Sharma, H.; Jespersen, N.; Ehrenbolger, K.; Carlson, L.-A.; Barandun, J.

10.1101/2023.05.31.543061 — biophysics — Posted on 2023-06-04

4017 Signal Improved ultra-Fast Light-sheet Microscope (SIFT) for large tissue imaging

Prince, M. N. H.; Garcia, B.; Henn, C.; Yi, Y.; Susaki, E. A.; Watakabe, Y.; Nemoto, T.; Lidke, K. A.; Zhao, H.; Salinas, I.; Liu, S.; Chakraborty, T.

10.1101/2023.05.31.543002 — biophysics — Posted on 2023-06-04

4018 Mechanism of substrate binding and transport in BASS transporters

Becker, P.; Naughton, F. B.; Brotherton, D. H.; Pacheco-Gomez, R.; Beckstein, O.; Cameron, A. D.

10.1101/2023.06.02.543391 — biochemistry — Posted on 2023-06-04

4019 Accurate identification of structural variations from cancer samples

Li, L.; Hong, C.; Xu, J.; Chung, C. Y.-L.; Leung, A. K.-Y.; Boncan, D. A. T.; Cheng, L.; Lo, K.-W.; Lai, P. B. S.; Wong, J.; Zhou, J.; Cheng, A. S.-L.; Chan, T.-F.; Yue, F.; Yip, K. Y.

10.1101/2023.05.31.543104 — genomics — Posted on 2023-06-04

4020 Intestinal epithelial adaptations to vertical sleeve gastrectomy defined at single-cell resolution

Koch-Laskowski, K. L.; Kim, K.-S.; Bethea, M.; Fuller, K. N. Z.; Sandoval, D. A.; Sethupathy, P.

10.1101/2023.05.31.543143 — genomics — Posted on 2023-06-04

4021 Dissecting neuron-specific functions of circadian genes using modified cell-specific CRISPR approaches

Richhariya, S.; Shin, D.; Le, J. Q.; Rosbash, M.

10.1101/2023.02.23.529279 — genetics — Posted on 2023-06-04

4022 Behavioral control through the direct, focal silencing of neuronal activity

Elleman, A. V.; Milicic, N.; Williams, D. J.; Liu, C. J.; Haynes, A. L.; Simko, J.; Ehrlich, D. E.; Makinson, C. D.; Du Bois, J.

10.1101/2023.05.31.543113 — neuroscience — Posted on 2023-06-04

4023 Cortical high-frequency oscillations ({approx} 110 Hz) in cats are state-dependent and enhanced by a subanesthetic dose of ketamine

Castro, S.; Gonzalez, J.; Cavelli, M. L.; Mateos, D. M.; Pascovich, C.; Tort, A. B.; Hunt, M. J.; Torterolo, P. D.

10.1101/2023.05.31.543142 — neuroscience — Posted on 2023-06-04

4024 Atg8-LC3 controls systemic nutrient surplus signaling from flies to humans.

Madan, A.; Kelly, K. P.; Sullivan, C. E.; Poling, M. E.; Brent, A. E.; Alassaf, M.; Dubrulle, J.; Rajan, A.

10.1101/2023.05.31.543119 — physiology — Posted on 2023-06-04

4025 Variation in thermal sensitivity of diapause development among individuals and over time drives life history timing patterns in an insect pest

Toxopeus, J.; Dowle, E. J.; Andaloori, L.; Ragland, G. J.

10.1101/2023.05.31.543112 — physiology — Posted on 2023-06-04

4026 Deep-learning Based Pathological Assessment of Frozen Procurement Kidney Biopsies Predicts Graft Loss and Guides Organ Utilization: A Large-scale Retrospective Study

Yi, Z.; Xi, C.; Menon, M. C.; Cravedi, P.; Tedla, F.; Soto, A.; Sun, Z.; Liu, K.; Zhang, J.; Wei, C.; Chen, M.; Wang, W.; Veremis, B.; Garcia-barros, M.; Kumar, A.; Haakinson, D.; Brody, R.; Gallon, L.; O'Connell, P.; Naesens, M.; Shapiro, R.; Colvin, R.; Ward, S.; Salem, F.; Zhang, W.

10.1101/2023.05.31.543098 — bioinformatics — Posted on 2023-06-04

4027 GeneToCN: An Alignment-Free Method for Gene Copy Number Estimation Directly from Next-Generation Sequencing Reads

Pajuste, F.-D.; Remm, M.

10.1101/2023.05.31.543012 — bioinformatics — Posted on 2023-06-04

4028 Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis

10.1101/2023.05.31.542971 — bioengineering — Posted on 2023-06-04

4029 Impairment of autophagy-lysosomal activity near the chronically implanted microelectrodes

Chen, K.; Garcia, C.; Kiselyov, K.; Kozai, T. D. Y.

10.1101/2023.05.31.543108 — bioengineering — Posted on 2023-06-04

4030 Pan-tissue mitochondrial phenotyping reveals lower OXPHOS expression and function across tumor types

Boykov, I.; Montgomery, M.; Hagen, J.; Aruleba, R.; McLaughlin, K.; Coalson, H.; Nelson, M.; Pereyra, A.; Ellis, J.; Zeczycki, T.; Vohra, N.; Tan, S.-F.; Cabot, M.; Fisher-Wellman, K.

10.1101/2023.06.04.542600 — biochemistry — Posted on 2023-06-04

4031 A NanoDam toolkit for tissue-specific transcription factor profiling in C. elegans

Yee, C.; Xiao, Y.; Katsanos, D.; Medwig-Kinney, T. N.; Zhang, W.; Shen, K.; Matus, D. Q.; Barkoulas, M.

10.1101/2023.05.31.543105 — genetics — Posted on 2023-06-04

4032 An abundant future for quagga mussels in deep European lakes

Kraemer, B. M.; Boudet, S.; Burlakova, L. E.; Haltiner, L.; Ibelings, B. W.; Karatayev, A. Y.; Karatayev, V. A.; Rossbacher, S.; Stoeckli, R.; Straile, D.; Piet, S.

10.1101/2023.05.31.543086 — ecology — Posted on 2023-06-04

4033 Chronotate: An open-source tool for manual timestamping and quantification of animal behavior

Philipsberg, P. A.; Christenson Wick, Z.; Diego, K. S.; Vaughan, N.; Galas, A.; Jurkowski, A.; Feng, Y.; Vetere, L. M.; Chen, L.; Cai, D. J.; Shuman, T.

10.1101/2023.05.31.543063 — neuroscience — Posted on 2023-06-04

4034 conn2res: A toolbox for connectome-based reservoir computing

Suarez, L. E.; Mihalik, A.; Milisav, F.; Marshall, K.; Li, M.; Vertes, P. E.; Lajoie, G.; Misic, B.

10.1101/2023.05.31.543092 — neuroscience — Posted on 2023-06-04

4035 Fast adaptation of feedforward connections through BTSP supports similarity search and explains the repulsion effect

Wu, Y.; Maass, W.

10.1101/2023.04.04.535572 — neuroscience — Posted on 2023-06-04

4036 Dicarboxylic acid supplementation protects from acute kidney injury via stimulation of renal peroxisomal activity

Barbosa, A. C. S.; Pfister, K. E.; Chiba, T.; Bons, J.; Rose, J.; Burton, J. B.; King, C. D.; O'Broin, A.; Young, V.; Zhang, B.; Sivakama, B.; Schmidt, A. V.; Uhlean, R.; Schilling, B.; Goetzman, E. S.; Sims-Lucas, S.

10.1101/2023.05.31.543068 — pathology — Posted on 2023-06-04

4037 Active surface flows accelerate the coarsening of lipid membrane domains

Arnold, D.; Gubbala, A.; Takatori, S. C.

10.1101/2023.05.31.543153 — biophysics — Posted on 2023-06-04

4038 kmindex and ORA: indexing and real-time user-friendly queries in terabytes-sized complex genomic datasets

Lemane, T.; Lezzoche, N.; Lecubin, J.; Pelletier, E.; Lescot, M.; Chikhi, R.; Peterlongo, P.

10.1101/2023.05.31.543043 — bioinformatics — Posted on 2023-06-04

4039 The phenological response of European vegetation to urbanisation is mediated by macrobioclimatic factors

Galan Diaz, J.; Gutierrez-Bustillo, A. M.; Rojo, J.

10.1101/2023.05.31.543030 — ecology — Posted on 2023-06-04

4040 Growth dynamics and genetic variation in attached and free-living populations of the filamentous brown seaweed, Pilayella littoralis

Miller, S. L.; Wilce, R. T.

10.1101/2023.05.31.543056 — ecology — Posted on 2023-06-04

4041 High-resolution Dynamic Human Brain Neural Activity Recording Using 3T MRI

Zhang, Y.; Sun, K.; Ren, J.; Hu, Q.; Wang, Y.; Li, S.; Chen, T.; Xu, N.; Guo, N.; Fu, X.; Liu, X.; Cao, Z.; Gao, J.-h.; Liu, H.

10.1101/2023.05.31.542967 — neuroscience — Posted on 2023-06-04

4042 Sub-Concussive Head Impacts From Heading Footballs Do Not Acutely Alter Brain Excitability As Compared to a Control Group

Hamel, R.; Waltzing, B. M.; Massey, T.; Blenkinsop, J.; McConnell, L.; Osborne, K.; Sesay, K.; Stoneman, F.; Carter, A.; Maaroufi, H.; Jenkinson, N.

10.1101/2023.05.31.543027 — neuroscience — Posted on 2023-06-04

4043 Time to degree, identity, and grant writing: Lessons learned from a mixed-methods longitudinal case study

Alvero, A.; Pena, C.; Moore, A. R.; Luqueno, L.; Barron, C. B.; Steele, L.; Eberle, S.; Botham, C. M.

10.1101/2023.01.26.525758 — scientific communication and education — Posted on 2023-06-04

4044 Temperature-dependent twist of double-stranded RNA probed by magnetic tweezers experiments and molecular dynamics simulations

Dohnalova, H.; Seifert, M.; Matouskova, E.; Papini, F. S.; Lipfert, J.; Dulin, D.; Lankas, F.

10.1101/2023.05.31.543084 — biophysics — Posted on 2023-06-04

4045 Chronic Prestress Regulation of Micro-Heart Muscle Physiology

Simmons, D. W.; Shuftan, D. R.; Guo, J.; Oguntuyo, K.; Ramahdita, G.; Munsell, M. K.; Kandalaft, B.; Pear, M.; Huebsch, N.

10.1101/2022.07.23.501265 — bioengineering — Posted on 2023-06-04

4046 DEVELOPMENTAL ULTRASTRUTCTURE MICROSCOPY IN DRUG DISCOVERY FROM DIOSCOREA SPECIES

Odimegwu, J. I.; Sangwan,, N. S.; Chanotiya, C. S.; Ogbonnia, S. O.; Odukoya, O. A.

10.1101/2023.04.07.535999 — developmental biology — Posted on 2023-06-04

4047 But, what are the cells doing? Image Analysis pipeline to follow single cells in the zebrafish embryo

Rama, A. B.; Venzin, O. F.; Rohde, L.; Chiaruttini, N.; Oates, A. C.

10.1101/2023.06.01.543221 — developmental biology — Posted on 2023-06-04

4048 Negative feedback on Retinoic Acid by Brachyury guides gastruloid symmetry-breaking

Hennessy, M. J.; Fulton, T.; Turner, D. A.; Steventon, B. J.

10.1101/2023.06.02.543388 — developmental biology — Posted on 2023-06-04

4049 Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics

Ankenbauer, K. E.; Rao, T. C.; Mattheyses, A. L.; Bellis, S. L.

10.1101/2023.06.03.543566 — cell biology — Posted on 2023-06-04

4050 Actin and microtubules position stress granules

Boeddeker, T. J.; Rusch, A.; Leeners, K.; Murrell, M. P.; Dufresne, E. R.

10.1101/2023.06.04.543599 — biophysics — Posted on 2023-06-04

4051 Sex-specific Proximal Tubular Cell differentiation pathways identified by single-nucleus RNA

Lu, Y. A.; Smith, T.; Deshpande, S.; Liao, C. T.; Talabani, B.; Grigorieva, I.; Mason, A.; Andrews, R.; Bowen, T.; Taylor, P.; Fraser, D.

10.1101/2023.06.02.543031 — cell biology — Posted on 2023-06-04

4052 CISD3 is required for Complex I function, mitochondrial integrity, and skeletal muscle maintenance

Marjault, H.-B.; Karmi, O.; Rowland, L.; Nguyen, T. T.; Grant, D.; Manrique-Acevedo, C.; Nechushtai, R.; Mittler, R.

10.1101/2023.06.03.543558 — cell biology — Posted on 2023-06-04

4053 Filament structure and subcellular organization of the bacterial intermediate filament-like protein crescentin

Liu, Y.; van den Ent, F.; Löwe, J.

10.1101/2023.06.04.543601 — microbiology — Posted on 2023-06-04

4054 Monitoring GPCR Conformation with GFP-Inspired Dyes

Belousov, A.; Maslov, I.; Orekhov, P.; Khorn, P.; Kuzmichev, P.; Baleeva, N.; Motov, V.; Bogorodskiy, A.; Krasnova, S.; Mineev, K.; Zinchenko, D.; Zernii, E.; Ivanovich, V.; Permyakov, S.; Hofkens, J.; Hendrix, J.; Cherezov, V.; Gensch, T.; Mishin, A.; Baranov, M. S.; Mishin, A.; Borshchevskiy, V.

10.1101/2023.06.01.543196 — biophysics — Posted on 2023-06-04

4055 A Pumpless, High-Throughput Microphysiological SystemConfirms Enteric Innervation of Duodenal Epithelium Strengthensthe Barrier Function

Nichols, K.; Snyder, J.; Koppes, R.; Koppes, A.

10.1101/2023.06.03.543561 — bioengineering — Posted on 2023-06-04

4056 Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy

Fejzo, M.; Rocha, N.; Cimino, I.; Lockhart, S. M.; Petry, C.; Kay, R. G.; Burling, K.; Barker, P.; George, A. L.; Yasara, N.; Premawardhena, A.; Gong, S.; Cook, E.; Rainbow, K.; Withers, D.; Cortessis, V.; Mullin, P.; MacGibbon, K.; Jin, E.; Kam, A.; Campbell, A.; Polasek, O.; Tzoneva, G.; Gribble, F.; Yeo, G.; Lam, B.; Saudek, V.; Hughes, I.; Ong, K.; Perry, J.; Sutton-Cole, A.; Baumgarten, M.; Welsh, P.; Sattar, N.; Smith, G. C.; Charnock-Jones, D. S.; Coll, A. P.; Meek, C. L.; Mettananda, S.; Hayward, C.; Mancuso, N.; O'Rahilly, S.

10.1101/2023.06.02.542661 — genetics — Posted on 2023-06-04

4057 Membrane-bound Interleukin-1α mediates leukocyte adhesion during atherogenesis

Maeder, C.; Speer, T.; Freichel, M.; Wirth, A.; Boeckel, J.-N.; Shahzad, K.; Fatima, S.; Isermann, B.; Laufs, U.; Gaul, S.

10.1101/2023.05.31.543077 — immunology — Posted on 2023-06-04

4058 Single-chain fluorescent integrators for mapping G-protein-coupled receptor agonists

Kroning, K. E.; Gannot, N.; Li, X.; Zhou, G.; Sescil, J.; Putansu, A.; Shen, J.; Wilson, A.; Fiel, H.; Li, P.; Wang, W.

10.1101/2023.05.31.543062 — bioengineering — Posted on 2023-06-04

4059 Growth plate resting zone chondrocytes acquire transient clonal competency upon Hedgehog activation and efficiently transform into trabecular bone osteoblasts

Orikasa, S.; Matsushita, Y.; Fogge, M.; Mizuhashi, K.; Sakagami, N.; Ono, W.; Ono, N.

10.1101/2023.05.31.543069 — developmental biology — Posted on 2023-06-04

4060 Chronic intermittent hypoxia induced-dysmetabolism is associated with hepatic oxidative stress, mitochondrial dysfunction and inflammation

Fernandes, J. L.; Martins, F. O.; Olea, E.; Prieto-LLoret, J.; Braga, P. C.; Sequeira, C. O.; Pereira, S. A.; Alves, M. G.; Rocher, A.; Conde, S. V.

10.1101/2023.05.31.543055 — physiology — Posted on 2023-06-04

4061 DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

Ma, R. K.; Tsai, P.-Y.; Farghli, A. R.; Shumway, A. J.; Kanke, M.; Gordan, J. D.; Gujral, T.; Vakili, K.; Nukaya, M.; Noetzli, L.; Ronnekleiv-Kelly, S.; Broom, W.; Barrow, J.; Sethupathy, P.

10.1101/2023.06.02.543290 — cancer biology — Posted on 2023-06-04

4062 HiTaC: a Hierarchical Taxonomic Classifier for Fungal ITS Sequences

Miranda, F. M.; Azevedo, V. A. C.; Ramos, R. T. J.; Renard, B. Y.; C. Piro, V.

10.1101/2020.04.24.014852 — bioinformatics — Posted on 2023-06-04

4063 Model discovery to link neural activity to behavioral tasks

Costabile, J. D.; Balakrishnan, K. A.; Schwinn, S.; Haesemeyer, M.

10.1101/2022.08.31.506108 — neuroscience — Posted on 2023-06-04

4064 Macaque Brainnetome Atlas: A Multifaceted Brain Map with Parcellation, Connection, and Histology

Lu, Y.; Cui, Y.; Cao, L.; Cheng, L.; Wang, C.; Liu, Y.; Zhang, B.; Wang, H.; Li, K.; Ma, L.; Shi, W.; Li, W.; Dong, Z.; Ma, Y.; Du, Z.; Zhang, J.; Xiong, H.; Luo, N.; Liu, Y.; Hou, X.; Liu, X.; Sun, H.; Wang, J.; Paxinos, G.; Yang, Z.; Fan, L.; Jiang, T.

10.1101/2022.10.18.512488 — neuroscience — Posted on 2023-06-04

4065 Identification of annotation artifacts concerning the CHALCONE SYNTHASE (CHS)

Bartas, M.; Volna, A.; Cerven, J.; Pucker, B.

10.1101/2023.03.18.533251 — bioinformatics — Posted on 2023-06-04

4066 Imaging membrane damage in ferroptosis and necrosis by wash-free fluorogenic chemical probes

Mauker, P.; Beckmann, D.; Kitowski, A.; Heise, C.; Wientjens, C.; Davidson, A. J.; Wood, W.; Wilhelm, C.; Thorn-Seshold, J.; Misgeld, T.; Kerschensteiner, M.; Thorn-Seshold, O.

10.1101/2023.06.02.543437 — molecular biology — Posted on 2023-06-03

4067 Genetic determinants of virulence and extensive drug resistance in Pseudomonas aeruginosa PPA14 isolated from eggplant rhizosphere

Ambreetha, S.; Parshatd, G.; Castellanos, C.; Narasimhan, G.; Balachandar, D.; Cickovski, T.; Mathee, K.

10.1101/2023.06.03.543547 — microbiology — Posted on 2023-06-04

4068 Mutant Huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure

Lisowski, P.; Lickfett, S.; Rybak-Wolf, A.; Le, S.; Dykstra, W.; mlody, b.; Menacho, C.; Roth, P.; Richter, y.; Kulka, L.; Glazar, P.; wu, h.; Meierhofer, D.; Legnini, I.; otto, m.; Miller, D.; neuendorf, n.; Hahn, t.; Telugu, N.; boeddrich, a.; Mayatepek, E.; Diecke, S.; olzscha, h.; kirstein, j.; Kuehn, R.; cambridge, s.; Rajewsky, N.; wanker, e.; priller, j.; Metzger, J.; Prigione, A.

10.1101/2023.06.03.543551 — neuroscience — Posted on 2023-06-04

4069 Attitudes Toward Cougar Restoration in Seven Eastern States

Carlson, S. C.; Vucetich, J. A.; Galiardi, L.; Bruskotter, J. T.

10.1101/2023.05.26.542322 — scientific communication and education — Posted on 2023-06-04

4070 A novel phenylpropanoid methyl esterase enables catabolism of aromatic compounds that inhibit biological nitrification

Wilson, A.; Van Fossen, E. M.; Shrestha, R.; Trotter, V. V.; Poirier, B.; Frank, A.; Nelson, W. C.; Kim, Y.-M.; Deutschbauer, A.; Egbert, R.; Elmore, J. R.

10.1101/2023.06.02.543320 — microbiology — Posted on 2023-06-03

4071 Targeting host sialic acids in the upper respiratory tract with a broadly-acting neuraminidase to inhibit influenza virus transmission

Ortigoza, M. B.; Mobini, C. L.; Rocha, H. L.; Bartlett, S.; Loomis, C. A.; Weiser, J. N.

10.1101/2023.06.02.543524 — microbiology — Posted on 2023-06-03

4072 Temporal composition of the cervicovaginal microbiome associates with hrHPV infection outcomes in a longitudinal study

Molina, M. A.; Leenders, W. P. J.; Huynen, M. A.; Melchers, W. J. G.; Andralojc, K. M.

10.1101/2023.06.02.543506 — microbiology — Posted on 2023-06-03

4073 Genetic determinants of virulence and extensive drug resistance in Pseudomonas aeruginosa PPA14 isolated from eggplant rhizosphere

Ambreetha, S.; Parshatd, G.; Castellanos, C.; Narasimhan, G.; Balachandar, D.; Cickovski, T.; Mathee, K.

10.1101/2023.06.03.543547 — microbiology — Posted on 2023-06-03

4074 Single-cell sequencing of individual retinal organoids reveals determinants of cell fate heterogeneity

Reh, T. A.; Trapnell, C.; Tresenrider, A.; Sridhar, A.; Eldred, K. C.; Cuschieri, S.; Hoffer, D.

10.1101/2023.05.31.543087 — genomics — Posted on 2023-06-04

4075 Assessment of environmental impacts based on particulate matter, and chlorophyll content of urban trees

Abriha-Molnar, V. E.; Szabo, S.; Magura, T.; Tothmeresz, B.; Abriha, D.; Sipos, B.; Simon, E.

10.1101/2023.05.31.543026 — ecology — Posted on 2023-06-03

4076 Single-cell lineage tracing reveals hierarchy and mechanism of adipocyte precursor maturation

Gonzalez, G. C. R.; Butka, E. G.; Gonzalez, C. E.; Kong, W.; Jindal, K.; Morris, S. A.

10.1101/2023.06.01.543318 — developmental biology — Posted on 2023-06-04

4077 The small protein MntS evolved from a signal peptide and acquired a novel function regulating manganese homeostasis in Escherichia coli

Wright, Z.; Seymour, M.; Paszczak, K.; Truttmann, T.; Senn, K.; Stilp, S.; Jansen, N.; Gosz, M.; Goeden, L.; Anantharaman, V.; Aravind, L.; Waters, L. S.

10.1101/2023.06.02.543501 — microbiology — Posted on 2023-06-03

4078 Differential encoding of temporal context and expectation under representational drift across hierarchically connected areas

Wyrick, D. G.; Cain, N.; Larsen, R. S.; Lecoq, J. G.; Valley, M.; Ahmed, R.; Bowlus, J.; Boyer, G.; Caldejon, S.; Casal, L.; Chvilicek, M.; Departee, M.; Groblewski, P.; Huang, C.; Johnson, K.; Kato, I.; Larkin, J. D.; Lee, E.; Liang, E.; Mace, K.; Nayan, C.; Nguyen, T.; Reding, M.; Seid, S.; Sevigny, J.; Stoecklin, M.; Williford, A.; Choi, H.; Garrett, M. E.; Mazzucato, L.

10.1101/2023.06.02.543483 — neuroscience — Posted on 2023-06-03

4079 Small regulatory RNAs are mediators of the Streptococcus mutans SloR regulon

Drummond, I. Y.; DePaolo, A.; Krieger, M.; Driscoll, H. E.; Eckstrom, K.; Spatafora, G. A.

10.1101/2023.06.02.543485 — microbiology — Posted on 2023-06-03

4080 A high throughput assay to measure Type VII secretion in Staphylococcus aureus

Yang, Y.; Alcock, F.; Kneuper, H.; Palmer, T.

10.1101/2023.06.03.543475 — microbiology — Posted on 2023-06-03

4081 LRG1 is a novel ligand of HER3 and promotes metastatic colorectal cancer growth

Rathore, M.; Wang, R.

10.1101/2023.02.18.529070 — cancer biology — Posted on 2023-06-03

4082 QTL Mapping of Seed Fe Concentration in an Interspecific RIL Population Derived from Lens culinaris x Lens ervoides

Podder, R.; Gela, T. S.; Bett, K. E.; Vandenberg, A.

10.1101/2023.06.01.543254 — genomics — Posted on 2023-06-03

4083 Reference-free multiplexed single-cell sequencing identifies genetic modifiers of the human immune response

Hartoularos, G. C.; Si, Y.; Zhang, F.; Kathail, P.; Lee, D.; Ogorodnikov, A.; Sun, Y.; Song, Y. S.; Kang, H. M.; Ye, C. J.

10.1101/2023.05.29.542756 — genomics — Posted on 2023-06-03

4084 Rewiring capsule production by CRISPRi-based genetic oscillators demonstrates a functional role of phenotypic variation in pneumococcal-host interactions

Rueff, A.-S.; van Raaphorst, R.; Aggarwal, S. D.; Santos-Moreno, J.; Laloux, G.; Schaerli, Y.; Weiser, J. N.; Veening, J.-W.

10.1101/2023.06.03.543575 — microbiology — Posted on 2023-06-03

4085 Interplay between nutrient transporters ensures fertility in the malaria mosquito Anopheles gambiae

Stryapunina, I.; Itoe, M.; Trinh, Q.; Vidoudez, C.; Du, E.; Mendoza, L.; Hulai, O.; Kauffman, J.; Carew, J.; Shaw, W. R.; Catteruccia, F.

10.1101/2023.06.02.543516 — microbiology — Posted on 2023-06-03

4086 Germinal centers are permissive to subdominant antibody responses

Robert, P. A.; Arulraj, T.; Meyer-Hermann, M.

10.1101/2023.05.31.543035 — systems biology — Posted on 2023-06-03

4087 Rewiring Saccharomyces cerevisiae metabolism for optimised Taxol(R) precursors production

Nowrouzi, B.; Torres-Montero, P.; Kerkhoven, E. J.; Martinez, J. L.; Rios Solis, L.

10.1101/2023.06.03.543533 — synthetic biology — Posted on 2023-06-03

4088 Discovery and engineering of hypercompact epigenetic modulators for durable gene activation

Carosso, G. A.; Yeo, R. W.; Gainous, T. B.; Jawaid, Z.; Yang, X.; Cutillas, V.; Qi, L. S.; Daley, T. P.; Hart, D.

10.1101/2023.06.02.543492 — synthetic biology — Posted on 2023-06-03

4089 rCRUX: A Rapid and Versatile Tool for Generating Metabarcoding Reference libraries in R

Curd, E. E.; Gal, L.; Gallego, R.; Nielsen, S.; Gold, Z.

10.1101/2023.05.31.543005 — bioinformatics — Posted on 2023-06-03

4090 Novel histones and histone variant families in prokaryotes

Schwab, S.; Boyle, A. L.; Dame, R. T.

10.1101/2023.06.01.543357 — bioinformatics — Posted on 2023-06-03

4091 De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity

Mout, R.; Bretherton, R. C.; Decarreau, J.; Lee, S.; Edman, N. I.; Ahlrichs, M.; Hsia, Y.; Sahtoe, D. D.; Ueda, G.; Gregorio, N.; Sharma, A.; Schulman, R.; DeForest, C. A.; Baker, D.

10.1101/2023.06.02.543449 — bioengineering — Posted on 2023-06-03

4092 Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

Diaz, R. E.; Ecker, A. K.; Correy, G. J.; Asthana, P.; Young, I. D.; Faust, B.; Thompson, M. C.; Seiple, I. B.; Van Dyken, S. J.; Locksley, R. M.; Fraser, J. S.

10.1101/2023.06.03.542675 — biochemistry — Posted on 2023-06-03

4093 Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe

Ouasti, F.; Audin, M.; Freon, K.; Quivy, J.-P.; Tachekort, M.; Cesard, E.; Thureau, A.; Ropars, V.; Varela, P. F.; Moal, G.; Soumana-Amadou, I.; Uryga, A.; Legrand, P.; Andreani, J.; Guerois, R.; Almouzni, G.; lambert, s. A.; Ochsenbein, F.

10.1101/2023.06.02.543505 — biochemistry — Posted on 2023-06-03

4094 Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition

Heil, L. R.; Damoc, N. E.; Arrey, T. N.; Pashkova, A.; Denisov, E.; Petzoldt, J.; Peterson, A.; Hsu, C.; Searle, B. C.; Shulman, N.; Riffle, M.; Connolly, B.; MacLean, B. X.; Remes, P. M.; Senko, M.; Stewart, H.; Hock, C.; Makarov, A.; Hermanson, D.; Zabrouskov, V.; Wu, C. C.; MacCoss, M. J.

10.1101/2023.06.03.543570 — biochemistry — Posted on 2023-06-03

4095 A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging

Emmanouilidis, L.; Bartalucci, E.; Kan, Y.; Ijavi, M.; Perez, M. E.; Afanasyev, P.; Boehringer, D.; Zehnder, J.; Parekh, S. H.; Bonn, M.; Michaels, T. C. T.; Wiegand, T.; Allain, F. H.- T.

10.1101/2023.06.02.542764 — biochemistry — Posted on 2023-06-03

4096 The ghrelin receptor GHSR has two efficient agonists in an ancient fish species

Li, H.-Z.; Wang, Y.-F.; Zheng, Y.-S.; Liu, Y.-L.; Xu, Z.-G.; Guo, Z.-Y.

10.1101/2023.06.03.543543 — biochemistry — Posted on 2023-06-03

4097 Accelerometer-based predictions of behaviour elucidate factors affecting the daily activity patterns of spotted hyenas

Minasandra, P.; Jensen, F. H.; Gersick, A. S.; Holekamp, K. E.; Strauss, E. D.; Strandburg-Peshkin, A.

10.1101/2023.05.31.543053 — animal behavior and cognition — Posted on 2023-06-03

4098 Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Mok, S.; Yeo, T.; Hong, D.; Shears, M. J.; Ross, L. S.; Ward, K. E.; Dhingra, S. K.; Kanai, M.; Bridgford, J. L.; Tripathi, A. K.; Mlambo, G.; Burkhard, A. Y.; Fairhurst, K. J.; Gil-Iturbe, E.; Park, H.; Rozenberg, F. D.; Kim, J.; Mancia, F.; Quick, M.; Uhlemann, A.-C.; Sinnis, P.; Fidock, D. A.

10.1101/2023.06.02.543338 — genomics — Posted on 2023-06-03

4099 When is sympatric speciation a possible evolutionary outcome?

Venkataraman, P.; Saini, S.

10.1101/2023.05.31.543051 — evolutionary biology — Posted on 2023-06-03

4100 Highly pathogenic avian influenza A virus (HPAIV) H5N1 infection in two European grey seals (Halichoerus grypus) with encephalitis.

Mirolo, M.; Pohlmann, A.; Ahrens, A.-K.; Kuehl, B.; Rubio-Garcia, A.; Kramer, K.; Meinfelder, U.; Rosenberger, T.; Morito, H.-L.; Beer, M.; Ludlow, M.; Wohlsein, P.; Baumgartner, W.; Harder, T.; Osterhaus, A.

10.1101/2023.05.30.542941 — ecology — Posted on 2023-06-03

4101 Spermidine facilitates the adhesion and subsequent invasion of Salmonella Typhimurium into epithelial cells via the regulation of surface adhesive structures and the SPI-1

Nair, A. V.; Devasurmutt, Y.; Rahman, S. A.; Tatu, U. S.; Chakravortty, D.

10.1101/2023.06.03.543567 — microbiology — Posted on 2023-06-03

4102 Mycobacterium trehalose polyphleates are required for infection by therapeutically useful mycobacteriophages BPs and Muddy

Wetzel, K. S.; Illouz, M.; Abad, L.; Aull, H. G.; Russell, D. A.; Garlena, R. A.; Cristinziano, M.; Malmsheimer, S.; Chalut, C.; Hatfull, G. F.; Kremer, L.

10.1101/2023.03.14.532567 — microbiology — Posted on 2023-06-03

4103 Persistent biofluid small molecule alterations induced by Trypanosoma cruzi infection are not restored by antiparasitic treatment

Dean, D. A.; Roach, J.; Ulrich vonBargen, R.; Xiong, Y.; Kane, S. S.; Klechka, L.; Wheeler, K.; Jimenez Sandoval, M.; Lesani, M.; Hossain, E.; Katemauswa, M.; Schaefer, M.; Harris, M.; Barron, S.; Liu, Z.; Pan, C.; McCall, L.-I.

10.1101/2023.06.03.543565 — microbiology — Posted on 2023-06-03

4104 P2X7 signaling mediates migraine-related augmentation of meningeal afferent mechanosensitivity

Zhao, J.; Harrison, S.; Levy, D.

10.1101/2023.02.02.526853 — neuroscience — Posted on 2023-06-03

4105 A single oscillating proto-hypothalamic neuron gates taxis behavior in the primitive chordate Ciona

Smith, W.; Chung, J.; Newman-Smith, E.; Kourakis, M. J.; Miao, Y.; Borba, C.; Medina, J.; Laurent, T.; Gallean, B.; Faure, E.

10.1101/2023.04.24.538092 — neuroscience — Posted on 2023-06-03

4106 Scene perception and visuospatial memory converge at the anterior edge of visually-responsive cortex

Steel, A.; Garcia, B. D.; Goyal, K.; Mynick, A.; Robertson, C. E.

10.1101/2022.11.14.516446 — neuroscience — Posted on 2023-06-03

4107 Autotrophic growth of E. coli is achieved by a small number of genetic changes

Ben Nissan, R.; Milshtein, E.; Pahl, V.; de Pins, B.; Jona, G.; Levi, D.; Yung, H.; Nir, N.; Ezra, D.; Gleizer, S.; Link, H.; Noor, E.; Milo, R.

10.1101/2023.06.03.543535 — synthetic biology — Posted on 2023-06-03

4108 Human subcutaneous adipose tissue variability is driven by VEGFA, ACTA2, adipocyte density, and ancestral history of the patient

DeBari, M. K.; Johnston, E. K.; Scott, J. V.; Iizuka, E.; Sun, W.; Webster-Wood, V. A.; Abbott, R. D.

10.1101/2023.05.31.543052 — physiology — Posted on 2023-06-03

4109 Condensate partitioning governs the mechanism of action of FUS phase separation modulators

Ausserwoeger, H.; Qian, D.; Krainer, G.; Welsh, T. J.; Sneideris, T.; Franzmann, T. M.; Qamar, S. S.; Nixon-Abell, J.; Kar, M.; St George-Hyslop, P.; Hyman, A. A.; Alberti, S.; Pappu, R. V.; Knowles, T. P. J.

10.1101/2023.05.31.543137 — biophysics — Posted on 2023-06-03

4110 Coiled-coil domains are sufficient to drive liquid-liquid phase separation of proteins in molecular models

Ramirez, D. A.; Hough, L. E.; Shirts, M. R.

10.1101/2023.05.31.543124 — biophysics — Posted on 2023-06-03

4111 Gel-assisted mass spectrometry imaging

Chan, Y. H.; Pathmasiri, K. C.; Pierre-Jacques, D.; Cologna, S. M.; Gao, R.

10.1101/2023.06.02.543480 — biochemistry — Posted on 2023-06-03

4112 Silk Road Revealed: Mechanism of silk fibre formation in Bombyx mori

Moreno-Tortolero, R. O.; Luo, Y.; Parmeggiani, F.; Skaer, N.; Walker, R.; Serpell, L. O.; Holland, C.; Davis, S. A.

10.1101/2023.06.02.543394 — biochemistry — Posted on 2023-06-03

4113 Amino acid substitutions hydrophilizing the core of titin domains cause dilated cardiomyopathy

Martinez-Martin, I.; Crousilles, A.; Ochoa, J. P.; Velazquez-Carreras, D.; Mortensen, S. A.; Herrero-Galan, E.; Dominguez, F.; Garcia-Pavia, P.; De Sancho, D.; Wilmanns, M.; Alegre-Cebollada, J.

10.1101/2023.06.02.543467 — biochemistry — Posted on 2023-06-03

4114 Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria

Rock, J. M.; Poulton, N. C.; DeJesus, M. A.; Munsamy-Govender, V.; Roberts, C. G.; Azadian, Z. A.; Bosch, B.; Lin, K. M.; Li, S.

10.1101/2023.06.02.543512 — microbiology — Posted on 2023-06-03

4115 A hybrid nitrogenase with regulatory elasticity in Azotobacter vinelandii

Rivier, A. J.; Myers, K. S.; Garcia, A. K.; Sobol, M. S.; Kacar, B.

10.1101/2023.06.02.543473 — microbiology — Posted on 2023-06-03

4116 Coiled-coil domains are sufficient to drive liquid-liquid phase separation of proteins in molecular models

Ramirez, D. A.; Hough, L. E.; Shirts, M. R.

10.1101/2023.05.31.543124 — biophysics — Posted on 2023-06-03

4117 After wounding, a G-protein coupled receptor restores tension to epithelial cells in a dynamic inward-traveling wave

Han, I.; Nassar, L. S.; Page-McCaw, A.; Hutson, M. S.

10.1101/2023.05.31.543122 — biophysics — Posted on 2023-06-03

4118 Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy

Brindley, E.; Heiland, M.; Mooney, C.; Mamad, O.; Hill, T.; Yan, Y.; Veno, M.; Reschke, C. R.; Batool, A.; Langa, E.; Rodriguez, A. S.; Morris, G.; Conboy, K.; Kjems, J.; Brennan, G.; Henshall, D.

10.1101/2023.06.02.542426 — neuroscience — Posted on 2023-06-03

4119 An efficient behavioral screening platform classifies natural products and other chemical cues according to their chemosensory valence in C. elegans

Fryer, E.; Guha, S.; Rogel-Hernandez, L. E.; Logan-Garbisch, T.; Farah, H. N.; Molhoff, I.; Rezaei, E.; Nekimken, A. L.; Xu, A.; Fechner, S.; Druckman, S.; Clandinin, T. R.; Rhee, S. Y.; Goodman, M. B.

10.1101/2023.06.02.542933 — neuroscience — Posted on 2023-06-03

4120 An ensemble of Gleditsia sinensis Lam. and gut microbiota against alcoholic liver disease

Oh, K.-K.; Yoon, S. J.; Lee, S.-B.; Lee, S. Y.; Gupta, H.; Ganesan, R.; Sharma, S. P.; Won, S.-M.; Jeong, J.-J.; Kim, D. J.; Suk, K. T.

10.1101/2023.05.31.543000 — systems biology — Posted on 2023-06-03

4121 Heat stress disrupts acid-base homeostasis independent of symbiosis in the model cnidarian Exaiptasia diaphana

Allen-Waller, L. R.; Jones, K. G.; Martynek, M. P.; Brown, K. T.; Barott, K. L.

10.1101/2023.05.31.543134 — physiology — Posted on 2023-06-03

4122 In Vivo Tissue Distribution of Microplastics and Systemic Metabolomic Alterations After Gastrointestinal Exposure

Garcia, M. M.; Romero, A. S.; Merkley, S. D.; Meyer-Hagen, J. L.; Forbes, C.; El Hayek, E.; Sciezka, D. P.; Templeton, R.; Gonzalez-Estrella, J.; Jin, Y.; Gu, H.; Benavidez, A.; Hunter, R. P.; Lucas, S.; Herbert, G.; Kim, K. J.; Cui, J. Y. Y.; Gullapalli, R.; In, J. G.; Campen, M. J.; Castillo, E. F.

10.1101/2023.06.02.542598 — pharmacology and toxicology — Posted on 2023-06-03

4123 Quality control and annotation of variant peptides identified through proteogenomics

Raj, A.; Aggarwal, S.; Yadav, A. K.; Dash, D.

10.1101/2023.05.31.542998 — bioinformatics — Posted on 2023-06-03

4124 In search of disentanglement in tandem mass spectrometry datasets

Abram, K. J.; McCloskey, D.

10.1101/2023.06.01.543126 — bioinformatics — Posted on 2023-06-03

4125 Genome wide assessment of genetic diversity and transcript variations in 17 accessions of the model diatom Phaeodactylum tricornutum

CHAUMIER, T.; YANG, F.; MANIRAKIZA, E.; AIT MOHAMED, O.; WU, Y.; CHANDOLA, U.; JESUS, B.; Piganeau, G.; Groisillier, A.; Tirichine, L.

10.1101/2023.05.31.543125 — genomics — Posted on 2023-06-03

4126 Adult-onset CNS sulfatide deficiency causes sex-dependent metabolic disruption in aging

Qiu, S.; He, S.; Wang, J.; Wang, H.; Bhattacharjee, A.; Li, X.; Saeed, M.; Dupree, J. L.; Han, X.

10.1101/2023.06.01.543121 — neuroscience — Posted on 2023-06-03

4127 Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior

Codeluppi, S. A.-M.; Xu, M.; Bansal, Y.; Lepack, A. E.; Duric, V.; Chow, M.; Muir, J.; Bagot, R. C.; Licznerski, P.; Wilber, S. L.; Sanacora, G.; Sibille, E.; Duman, R.; Pittenger, C.; Banasr, M.

10.1101/2023.05.31.542974 — neuroscience — Posted on 2023-06-03

4128 Simultaneous neuronal expression of human amyloid-β and Tau genes drives global phenotypic and multi-omic changes in C. elegans

Holcom, A.; Fuentealba, M.; Sivapatham, R.; King, C. D.; Osman, H.; Foulger, A.; Bhaumik, D.; Schilling, B.; Furman, D.; Andersen, J. K.; Lithgow, G. J.

10.1101/2023.06.01.542377 — systems biology — Posted on 2023-06-03

4129 A structural and dynamic visualization of the interaction between the microtubule-associated protein 7 (MAP7) and microtubules

Adler, A.; Bangera, M.; Bahri, S.; van Ingen, H.; Moores, C.; Baldus, M.

10.1101/2023.06.02.543398 — biophysics — Posted on 2023-06-03

4130 Construction and representation of human pangenome graphs

Andreace, F.; Lechat, P.; Dufresne, Y.; Chikhi, R.

10.1101/2023.06.02.542089 — bioinformatics — Posted on 2023-06-03

4131 A combined computational and experimental investigation of the filtration function of splenic macrophages in sickle cell disease

li, g.; Qiang, Y.; Li, H.; Li, X.; Buffet, P. A.; Dao, M.; Karniadakis, G. E.

10.1101/2023.05.31.543007 — bioengineering — Posted on 2023-06-03

4132 Doublecortin regulates neuronal migration by editing the tubulin code

Sebastien, M.; Prowse, E. N. P.; Hendricks, A. G.; Brouhard, G. J.

10.1101/2023.06.02.543327 — cell biology — Posted on 2023-06-03

4133 Extracting thermodynamic properties from van 't Hoff plots with emphasis on temperature-sensing ion channels

Bullerjahn, J. T.; Hanson, S. M.

10.1101/2023.06.02.543442 — biophysics — Posted on 2023-06-03

4134 Fitting high-resolution electron density maps from atomic models to solution scattering data

Chamberlain, S. R.; Moore, S.; Grant, T. D.

10.1101/2023.06.02.543451 — biophysics — Posted on 2023-06-03

4135 Revisiting the use of dioxane as a reference compound for determination of the hydrodynamic radius of proteins by pulsed field gradient NMR spectroscopy

Tranchant, E. E.; Pesce, F.; Jacobsen, N. L.; Fernandes, C. B.; Kragelund, B. B.; Lindorff-Larsen, K.

10.1101/2023.06.02.543514 — biophysics — Posted on 2023-06-03

4136 Identifying Membrane Protein-Lipid Interactions with Lipidomic Lipid Exchange-Mass Spectrometry

Zhang, G.; Odenkirk, M. T.; Janczak, C. M.; Lee, R.; Richardson, K.; Wang, Z.; Aspinwall, C. A.; Marty, M. T.

10.1101/2023.06.02.543293 — biophysics — Posted on 2023-06-03

4137 YAP/TAZ enhance P-body formation to promote tumorigenesis

Shen, X.; Peng, X.; Guo, Y.; Dai, Z.; Cui, L.; Yu, W.; Liu, Y.; Liu, C.-Y.

10.1101/2023.06.02.542626 — cell biology — Posted on 2023-06-03

4138 A lipid transfer protein knockout library reveals ORP9-ORP11 dimer mediating PS/PI(4)P exchange at the ER-trans Golgi contact site to promote sphingomyelin synthesis

Cabukusta, B.; Borst Pauwels, S.; Akkermans, J. J. L. L.; Blomberg, N.; Mulder, A. A.; Koning, R. I.; Giera, M.; Neefjes, J.

10.1101/2023.06.02.543249 — cell biology — Posted on 2023-06-03

4139 Absence of electron transfer-associated changes in the time-dependent X-ray free-electron laser structures of the photosynthetic reaction center

Nishikawa, G.; Sugo, Y.; Saito, K.; Ishikita, H.

10.1101/2023.05.31.543167 — biophysics — Posted on 2023-06-03

4140 Endosome-ER Interactions Define a Cellular Energy Landscape to Guide Cargo Transport

Shen, Y.; Wen, Y.; Zhao, Q.; Huang, P.; Lai, P.-Y.; Tong, P.

10.1101/2023.06.01.543348 — biophysics — Posted on 2023-06-03

4141 Finetuning ERK activity enables most somatic cells to reprogram into pluripotency

Wu, Q.; Zhang, J.; Hu, X.; Mafra de Faria, B.; Scalf, S. M.; Karatepe, K.; Roy, A. L.; Guo, S.

10.1101/2023.06.02.543427 — cell biology — Posted on 2023-06-03

4142 A mitochondrial sirtuin shapes the intestinal microbiota by controlling lysozyme expression

Knop, M.; Treitz, C.; Bettendorf, S.; Bossen, J.; von Frieling, J.; Doms, S.; Bruchhaus, I.; Kuehnlein, R.; Baines, J. F.; Tholey, A.; Roeder, T.

10.1101/2023.06.02.543385 — cell biology — Posted on 2023-06-03

4143 Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics

Kubori, T.; Arasaki, K.; Kitao, T.; Nagai, H.

10.1101/2023.06.02.543523 — microbiology — Posted on 2023-06-03

4144 TPPP Forms Liquid Condensates and Aggregates in Multiple System Atrophy

Kemal, S.; Richardson, H. S.; McAlear, T. S.; Kopach, A.; Nowacki, J. C.; Li, Y.; Bechstedt, S.; Fu, M.-m.

10.1101/2023.05.31.542915 — neuroscience — Posted on 2023-06-03

4145 Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states

Lin, D. Y.-w.; Kueffer, L. E.; Juneja, P.; Wales, T. E.; Engen, J. R.; Andreotti, A. H.

10.1101/2023.06.02.543453 — biophysics — Posted on 2023-06-03

4146 Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting

Wu, Y.; Yan, Y.; Yang, Y.; Bian, S.; Rivetta, A.; Allen, K.; Sigworth, F. J.

10.1101/2023.06.02.543446 — biophysics — Posted on 2023-06-03

4147 Resolving conformational changes that mediate a two-step catalytic mechanism in a model enzyme

Greisman, J. B.; Dalton, K. M.; Brookner, D. E.; Klureza, M. A.; Sheehan, C. J.; Kim, I.-S.; Henning, R. W.; Russi, S.; Hekstra, D. R.

10.1101/2023.06.02.543507 — biophysics — Posted on 2023-06-03

4148 High-resolution structure of mouse radial spoke and its in-situ structure in ependymal cilia revealed by cryo-EM and cryo-ET

Meng, X.; Xu, C.; Li, J.; Qiu, B.; Luo, J.; Hong, Q.; Tong, Y.; Fang, C.; Feng, Y.; Ma, R.; Shi, X.; Lin, C.; Pan, C.; Zhu, X.; Yan, X.; Cong, Y.

10.1101/2023.06.02.543457 — biophysics — Posted on 2023-06-03

4149 The landscape of cancer rewired GPCR signaling axes

Arora, C.; Matic, M.; DiChiaro, P.; Rosa, N. D. O.; Nemati, L.; Clubb, L.; Kargas, G.; Diaferia, G.; Vukotic, R.; Licata, L.; Wu, G.; Natoli, G.; Gutkind, J. S.; Raimondi, F.

10.1101/2023.03.13.532291 — bioinformatics — Posted on 2023-06-03

4150 Interactions Between the Histone Variant H2Av and the Suppressor of Hairy wing Insulator Influence the DNA Damage Response and Lymph Gland Development in Drosophila

Simmons, J. R.; Kemp, J. D. J.; Labrador, M.

10.1101/2023.05.31.543180 — molecular biology — Posted on 2023-06-02

4151 Estimating multiplicity of infection, allele frequencies, and prevalences accounting for incomplete data

Hashemi, M.; Schneider, K. A.

10.1101/2023.06.01.543300 — molecular biology — Posted on 2023-06-02

4152 Multimodal analysis of neuronal maturation in the developing primate prefrontal cortex

Gao, Y.; Dong, Q.; Arachchilage, K. H.; Risgaard, R.; Sheng, J.; Syed, M.; Schmidt, D. K.; Jin, T.; Liu, S.; Doherty, D.; Glass, I.; Levine, J. E.; Wang, D.; Chang, Q.; Zhao, X.; Sousa, A. M.

10.1101/2023.06.02.543460 — neuroscience — Posted on 2023-06-03

4153 Progranulin maintains blood pressure and vascular tone dependent on EphrinA2 and Sortilin1 receptors and eNOS activation

Bruder-Nascimento, A.; Awata, W. M. C.; Alves, J. V.; Singh, S.; Costa, R. M.; Bruder-Nascimento, T.

10.1101/2023.04.02.534563 — pharmacology and toxicology — Posted on 2023-06-03

4154 SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms

Pardo-Palacios, F.; Arzalluz-Luque, A.; Kondratova, L.; Salguero, P.; Mestre-Tomas, J.; Amorin, R.; Estevan-Morio, E.; Liu, T.; Nanni, A.; McIntyre, L. M.; Tseng, E.; Conesa, A.

10.1101/2023.05.17.541248 — bioinformatics — Posted on 2023-06-03

4155 Learning structural heterogeneity from cryo-electron sub-tomograms with tomoDRGN

Powell, B. M.; Davis, J. H.

10.1101/2023.05.31.542975 — molecular biology — Posted on 2023-06-02

4156 pOPARA: Vectors for Golden Gate assembly of expression constructs containing the araBAD promoter

Milnes, L.; Youles, M.; Maidment, J. H.

10.1101/2023.05.31.543011 — molecular biology — Posted on 2023-06-02

4157 Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases

Altay, M. F.; Kumar, S. T.; Burtscher, J.; Jagannath, S.; Strand, C.; Miki, Y.; Parkkinen, L.; Holton, J. L.; Lashuel, H. A.

10.1101/2022.05.26.493598 — neuroscience — Posted on 2023-06-03

4158 Preference Shifts During Multi-Attribute Value-Based Decisions

Nakahashi, A.; Cisek, P.

10.1101/2023.05.10.540218 — neuroscience — Posted on 2023-06-03

4159 Assessing the performance of commercial reagent antibodies

Ayoubi, R.; Ryan, J.; Fotouhi, M.; Alshafie, W.; Bolivar, S. G.; Moleon, V. R.; Reintsch, W.; Eckmann, P.; Worrall, D.; McDowell, I.; Southern, K.; Durcan, T. M.; Bandrowski, A. E.; Virk, H. S.; McPherson, P. S.; Edwards, A. M.; Laflamme, C.

10.1101/2023.06.01.543292 — molecular biology — Posted on 2023-06-02

4160 Thrombospondin 2 is a key determinant of fibrogenesis in NAFLD

Kimura, T.; Iwadare, T.; Wakabayashi, S.-i.; Kuldeep, S.; Nakajima, T.; Yamazaki, T.; Aomura, D.; Zafar, H.; Iwaya, M.; Uehara, T.; Pydi, S. P.; Tanaka, N.; Umemura, T.

10.1101/2023.06.01.543250 — molecular biology — Posted on 2023-06-02

4161 Single-component multilayered self-assembling protein nanoparticles displaying extracellular domains of matrix protein 2 as a pan-influenza A vaccine

Gomes, K. B.; Zhang, Y.-N.; Lee, Y.-Z.; Eldad, M.; Lim, A.; Ward, G.; Auclair, S.; He, L.; Zhu, J.

10.1101/2023.06.02.543464 — microbiology — Posted on 2023-06-02

4162 Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in northeast Thailand

Seng, R.; Tandhavanant, S.; Saiprom, N.; Phunpang, R.; Chomkatekaew, C.; Thaipadungpanit, J.; Batty, E. M.; Thomson, N. R.; Chantratita, W.; West, T. E.; Chewapreecha, C.; Chantratita, N.

10.1101/2023.06.02.543359 — microbiology — Posted on 2023-06-02

4163 Phylodynamics Uncovers the Transmission of Antibiotic-Resistant Escherichia coli between Canines and Humans in an Urban Environment

Walas, N.; Müller, N. F.; Parker, E.; Henderson, A.; Capone, D.; Brown, J.; Barker, T.; Graham, J. P.

10.1101/2023.06.01.543064 — microbiology — Posted on 2023-06-03

4164 Better together: Objects in familiar constellations evoke high-level representations of real-world size

Quek, G. L.; Theodorou, A.; Peelen, M. V.

10.1101/2023.05.30.542965 — neuroscience — Posted on 2023-06-03

4165 Copper reduces the virulence of bacterial communities at environmentally relevant concentrations

Lear, L.; Padfield, D.; Hesse, E.; Kay, S.; Buckling, A.; Vos, M.

10.1101/2023.06.02.543412 — microbiology — Posted on 2023-06-02

4166 Iron chelation by deferoxamine as useful adjunct therapeutics in murine tuberculosis.

Kaushik, S. R.; Sahu, S.; MOHAPATRA, A. K.; Yadav, N.; Sarangi, A.; Kumari, S.; Biswal, B.; Nanda, R.

10.1101/2023.06.02.543389 — microbiology — Posted on 2023-06-02

4167 The Src and Abl family kinases activate the Spleen Tyrosine Kinase to maximize phagocytosis and Leishmania infection

Ullah, I.; Barrie, U.; Kernen, R. M.; Mamula, E. T.; Khuong, F. T. H.; Booshehri, L. M.; Rhodes, E. L.; Bradford, J. M.; Datta, A.; Wetzel, D. M.

10.1101/2022.11.14.513575 — microbiology — Posted on 2023-06-02

4168 Unveiling Convergent and Divergent Intrinsic Brain Network Alternations in Depressed Adolescents Engaged Non-Suicidal Self-Injurious Behaviors with and without Suicidal Attempts

Li, L.; Liang, Z.; Li, G.; Xu, H.; Yang, X.; Liu, X.; Zhang, X.; Wang, J.; Zhang, Z.; Zhou, Y.

10.1101/2023.03.09.531863 — neuroscience — Posted on 2023-06-03

4169 Deep Phenotyping of the Lipidomic Response in COVID and non-COVID Sepsis

Meng, H.; Sengupta, A.; Riccioti, E.; Mrcela, A.; Mathew, D.; Mazaleuskaya, L.; Ghosh, S.; Brooks, T.; Turner, A.; Schanoski, A.; Lahens, N.; Tan, A. W.; Woolfork, A.; Grant, G.; Susztak, K.; Letizia, A.; Sealfon, S.; Wherry, E. J.; Laudanski, K.; Weljie, A.; Meyer, N.; Fitzgerald, G.

10.1101/2023.06.02.543298 — systems biology — Posted on 2023-06-02

4170 Repressing ABCB7 Potentiates Cisplatin Response in Pediatric Group 3 Medulloblastoma by Triggering Ferroptosis

Kanchan, R. K.; Perumal, N.; Khan, P.; Doss, D.; Gopalakrishnan, P.; Chirravuri Venkata, R.; Thapa, I.; Vengoji, R.; Kaushal, J.; Siddiqui, J. A.; Nasser, M. W.; Batra, S. K.; Mahapatra, S.

10.1101/2022.01.24.477587 — cancer biology — Posted on 2023-06-03

4171 Principles for Optimal Window Size Selection for Infant and Adult EEG Connectivity Analysis

Santamaria, L.; Canales-Johnson, A.; Noreika, V.; Leong, V.

10.1101/2023.05.31.542996 — neuroscience — Posted on 2023-06-02

4172 Dendritic voltage imaging reveals biophysical basis of associative plasticity rules

Park, P.; Wong-Campos, J. D.; Itkis, D.; Qi, Y.; Davis, H. C.; Grimm, J. B.; Plutkis, S. E.; Lavis, L.; Cohen, A. E.

10.1101/2023.06.02.543490 — neuroscience — Posted on 2023-06-02

4173 Mapping temperature-sensitive mutations at a genome-scale to engineer growth-switches in E. coli

Schramm, T.; Pahl, V.; Link, H.

10.1101/2023.06.01.543195 — systems biology — Posted on 2023-06-02

4174 Morphological brain networks of white matter: mapping, evaluation, characterization and application

Li, J.; Li, Z.; Yang, Y.; Luo, Z.; Liu, Y.; Wang, J.

10.1101/2023.06.02.543370 — neuroscience — Posted on 2023-06-02

4175 Demonstration that sublinear dendrites enable linearly non-separable computations

Caze, R. D.; Tran-Van-Minh, A.; Gutkin, B.; DiGregorio, D.

10.1101/2023.06.01.543223 — neuroscience — Posted on 2023-06-02

4176 Coherent feedback leads to robust background compensation in oscillatory and non-oscillatory homeostats

Nygard, M.; Ruoff, P.

10.1101/2023.05.30.542992 — systems biology — Posted on 2023-06-02

4177 Inter and Intralaminar Excitation of Parvalbumin Interneurons in Mouse Barrel Cortex

Scheuer, K. S.; Jansson, A. M.; Zhao, X.; Jackson, M. B.

10.1101/2023.06.02.543448 — neuroscience — Posted on 2023-06-02

4178 Multimodal analysis of neuronal maturation in the developing primate prefrontal cortex

Gao, Y.; Dong, Q.; Arachchilage, K. H.; Risgaard, R.; Sheng, J.; Syed, M.; Schmidt, D. K.; Jin, T.; Liu, S.; Doherty, D.; Glass, I.; Levine, J. E.; Wang, D.; Chang, Q.; Zhao, X.; Sousa, A. M.

10.1101/2023.06.02.543460 — neuroscience — Posted on 2023-06-02

4179 Uncovering the role that specific genes play in reachability properties of complex biological Gene Regulatory Networks (GRNs): The Arabidopsis thaliana flower development case

Chairez-Veloz, J. E.; Chavez-Hernandez, E. C.; Davila-Velderrain, J.; Alvarez-Buylla, E. R.; Martinez-Garcia, J. C.

10.1101/2023.05.30.542986 — systems biology — Posted on 2023-06-02

4180 Modulation of antigen discrimination by duration of immune contacts in a kinetic proofreading model of T cell activation with extreme statistics.

Morgan, J.; Lindsay, A.

10.1101/2023.05.30.542789 — systems biology — Posted on 2023-06-02

4181 Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

Podmore, L. M.; Poloz, Y.; Iorio, C.; Mouaaz, S.; Nixon, K.; Smirnov, P.; McDonnell, B.; Lam, S.; Zhang, B.; Tharmapalan, P.; Vyas, F.; Ennis, M.; Dowling, R.; Stambolic, V.

10.1101/2022.05.06.490906 — cancer biology — Posted on 2023-06-02

4182 A zebrafish xenotransplant model of anaplastic thyroid cancer to study the tumor microenvironment and innate immune cell interactions in vivo.

Michael, C.; Di Cristofano, A.; de Oliveira, S.

10.1101/2023.05.29.541816 — cancer biology — Posted on 2023-06-02

4183 Integrative identification of non-coding regulatory regions driving metastatic prostate cancer

Woo, B. J.; Moussavi-Baygi, R.; Karner, H.; Karimzadeh, M.; Garcia, K.; Joshi, T.; Yin, K.; Navickas, A.; Gilbert, L. A.; Wang, B.; Asgharian, H.; Feng, F. Y.; Goodarzi, H.

10.1101/2023.04.14.535921 — cancer biology — Posted on 2023-06-02

4184 The PALB2 DNA binding domain is an intrinsically disordered recombinase.

Kyriukha, Y.; Watkins, M. B.; Redington, J. M.; Hopkins, J. B.; Dastvan, R.; Pozzi, N.; Korolev, S.

10.1101/2023.06.01.543259 — biophysics — Posted on 2023-06-02

4185 A multiscale theory for spreading and migration of adhesion-reinforced mesenchymal cells

Shu, W.; Kaplan, C. N.

10.1101/2023.05.03.539193 — biophysics — Posted on 2023-06-02

4186 Social dynamics of vervet monkeys are dependent upon group identity.

Kerjean, E.; van de Waal, E.; Canteloup, C.

10.1101/2023.06.02.543415 — animal behavior and cognition — Posted on 2023-06-02

4187 In vitro modelling of anterior primitive streak patterning with hESC reveals the dynamic of WNT and NODAL signalling required to specify notochord progenitors

Garcia, M. R.; Thimonier, C.; Angoura, K.; Ozga, E.; MacPherson, H.; Blin, G.

10.1101/2023.06.01.543323 — developmental biology — Posted on 2023-06-02

4188 Symmetry in frontal but not motor and somatosensory corticocortical and corticostriatal circuitry

Papale, A. E.; Harish, M.; Paletzki, R. F.; O'Connor, N. J.; Eastwood, B. S.; Seal, R. P.; Williamson, R. S.; Gerfen, C. R.; Hooks, B. M.

10.1101/2023.06.02.543431 — neuroscience — Posted on 2023-06-02

4189 Electrophysiological correlates of (mis)judging social information

Wischnewski, M.; Hörberg, M. O. Y.; Schutter, D. J. L. G.

10.1101/2023.06.02.543470 — neuroscience — Posted on 2023-06-02

4190 Calcium-triggered DNA-mediated membrane fusion in synthetic cells

Hsu, Y.-Y.; Chen, S. J.; Bernal-Chanchavac, J.; Sharma, B.; Moghimianavval, H.; Stephanopoulos, N.; Liu, A. P.

10.1101/2023.05.06.539684 — synthetic biology — Posted on 2023-06-02

4191 Metabuli: sensitive and specific metagenomic classification via joint analysis of amino-acid and DNA

Kim, J.; Steinegger, M.

10.1101/2023.05.31.543018 — bioinformatics — Posted on 2023-06-02

4192 Deep learning from harmonized peptide libraries enables retention time prediction of diverse post translational modifications

Wilburn, D. B.; Shannon, A. E.; Spicer, V.; Richards, A. L.; Yeung, D.; Swaney, D. L.; Krokhin, O. V.; Searle, B. C.

10.1101/2023.05.30.542978 — bioinformatics — Posted on 2023-06-02

4193 Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex

Chen, M.; Ren, X.; Cook, A. S. I.; Hurley, J. H.

10.1101/2023.06.01.543278 — biochemistry — Posted on 2023-06-02

4194 Computational Framework for Statistical Epistasis Supports XOR Penetrance Function in a Living System

Batista, S.; Madar, V.; Freda, P. J.; Bhandary, P.; Ghosh, A.; Chitre, A. S.; Palmer, A. A.; Moore, J. H.

10.1101/2023.05.09.539940 — genetics — Posted on 2023-06-02

4195 A conserved RWP-RK transcription factor VSR1 controls gametic differentiation in volvocine algae

Geng, S.; Hamaji, T.; Ferris, P. J.; Gao, M.; Nishimura, Y.; Umen, J. G.

10.1101/2023.03.26.534280 — genetics — Posted on 2023-06-02

4196 Gene Gain and Loss from the Asian Corn Borer W Chromosome

Dai, W.; Mank, J. E.; Ban, L.

10.1101/2022.10.21.512844 — evolutionary biology — Posted on 2023-06-02

4197 The nitrogenase G-subunit is an ancient orphan protein that drove the ecological expansion of nitrogen fixation

Cuevas Zuviria, B.; Garcia, A. K.; Carruthers, B.; Kacar, B.

10.1101/2023.04.03.535378 — evolutionary biology — Posted on 2023-06-02

4198 Reconstructing cell type evolution across species through cell phylogenies of single-cell RNAseq data

Mah, J. L.; Dunn, C. W.

10.1101/2023.05.18.541372 — evolutionary biology — Posted on 2023-06-02

4199 Hedgehog signaling via its ligand DHH acts as cell fate determinant during skeletal muscle regeneration

Norris, A. M.; Appu, A.; Johnson, C. D.; Zhou, L. Y.; McKellar, D. W.; Renault, M.-A.; Hammers, D. W.; Cosgrove, B. D.; Kopinke, D.

10.1101/2022.08.15.504012 — developmental biology — Posted on 2023-06-02

4200 Clinorotation inhibits myotube formation by fluid motion, not by simulated microgravity

Mansour, J.; Berwanger, C.; Jung, M.; Eichinger, L.; Fabry, B.; Clemen, C. S.

10.1101/2023.02.10.527979 — cell biology — Posted on 2023-06-02

4201 Defining Vaginal Community Dynamics: daily microbiome transitions, the role of menstruation, bacteriophages and bacterial genes

Hugerth, L. W.; Krog, M. C.; Vomstein, K.; Du, J.; Bashir, Z.; Kaldhusdal, V.; Fransson, E.; Engstrand, L.; Nielsen, H. S.; Schuppe-Koistinen, I.

10.1101/2023.06.02.543379 — microbiology — Posted on 2023-06-02

4202 Ribosome profiling reveals the fine-tuned response of Escherichia coli to mild and severe acid stress

Schumacher, K.; Gelhausen, R.; Kion-Crosby, W.; Barquist, L.; Backofen, R.; Jung, K.

10.1101/2023.06.02.543275 — microbiology — Posted on 2023-06-02

4203 Exoribonuclease RNase R protects Antarctic Pseudomonas syringae Lz4W from DNA damage and oxidative stress

Mittal, P.; Sipani, R.; Pandiyan, A.; Sulthana, S.; Sinha, A. K.; Hussain, A.; Ray, M. K.; Pavankumar, T. L.

10.1101/2023.06.01.543265 — microbiology — Posted on 2023-06-02

4204 Modeling Versatile and Dynamic Anaerobic Metabolism for PAOs/GAOs Competition Using Agent-based Model and Verification via Single Cell Raman Micro-spectroscopy

Li, G.; Tooker, N. B.; Wang, D.; Srinivasan, V.; Barnard, J. L.; Russel, A.; Stinson, B.; McQuarrie, J.; Schauer, P.; Menniti, A.; Varga, E.; Hauduc, H.; Takacs, I.; Bott, C.; Dombrowski, P.; Onnis-Hayden, A.; Gu, A. Z.

10.1101/2020.11.18.387589 — microbiology — Posted on 2023-06-02

4205 Illusion of illusion: A spatial-attentional mechanism underlies action-related distortions of time perception

Cao, L.

10.1101/2022.10.21.513155 — neuroscience — Posted on 2023-06-02

4206 A tonically active master neuron continuously modulates mutually exclusive motor states at two-time scales

Meng, J.; Ahamed, T.; Yu, B.; Hung, W.; El Mouridi, S.; Zhang, Z.; Wang, Z.; Wen, Q.; Boulin, T.; Gao, S.; Zhen, M.

10.1101/2022.04.06.487231 — neuroscience — Posted on 2023-06-02

4207 Mechanotropic bZIP localization is associated with thigmomorphogenic and secondary cell wall associated gene expression

Coomey, J. H.; MacKinnon, K. J.-M.; McCahill, I. W.; Khahani, B.; Handakumbura, P.; Trabucco, G. M.; Mazzola, J.; Leblanc, N. A.; Kheam, R.; Hernandez-Romero, M.; Barry, K. W.; Liu, L.; Lee, J. E.; Vogel, J. P.; O'Malley, R.; Chambers, J. J.; Hazen, S. P.

10.1101/2021.02.03.429573 — plant biology — Posted on 2023-06-02

4208 High-resolution kinetics of herbivore-induced plant volatile transfer reveal tightly clocked responses in neighboring plants

Waterman, J. M.; Wang, L.; Cofer, T. M.; Erb, M.

10.1101/2023.05.21.541613 — plant biology — Posted on 2023-06-02

4209 Alterations in RNA editing in skeletal muscle following exercise training in individuals with Parkinsons disease

Mercer, H. M.; Nair, A. M.; Ridgel, A.; Piontkivska, H.

10.1101/2023.05.30.542987 — bioinformatics — Posted on 2023-06-02

4210 zDB: bacterial comparative genomics made easy

Marquis, B.; Pillonel, T.; Carrara, A.; Bertelli, C.

10.1101/2023.05.31.543076 — bioinformatics — Posted on 2023-06-02

4211 Large Scale Foundation Model on Single-cell Transcriptomics

Hao, M.; Gong, J.; Zeng, X.; Liu, C.; Guo, Y.; Cheng, X.; Wang, T.; Ma, J.; Song, L.; Zhang, X.

10.1101/2023.05.29.542705 — bioinformatics — Posted on 2023-06-02

4212 gtexture: novel extension of image texture analysis to graphs and its application to cancer informatics

Barker-Clarke, R. J.; Weaver, D.; Scott, J. G.

10.1101/2022.11.21.517417 — bioinformatics — Posted on 2023-06-02

4213 AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development for mRNA Delivery

Xu, Y.; Ma, S.; Cui, H.; Chen, J.; Xu, S.; Wang, K.; Varley, A.; Lu, R. X. Z.; Bo, W.; Li, B.

10.1101/2023.06.01.543345 — biochemistry — Posted on 2023-06-02

4214 Terminal maturation of human reticulocytes to red blood cells by extensive remodelling and progressive liquid ordering of membrane lipids

Minetti, G.; Kaestner, L.; Dorn, I.

10.1101/2023.06.02.543386 — biochemistry — Posted on 2023-06-02

4215 A marine cryptochrome with an inverse photo-oligomerization mechanism

Vu, H. H.; Behrmann, H.; Hanic, M.; Jeyasankar, G.; Krishnan, S.; Dannecker, D.; Hammer, C.; Gunkel, M.; Solovyov, I. A.; Wolf, E.; Behrmann, E.

10.1101/2023.06.02.543409 — biochemistry — Posted on 2023-06-02

4216 NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing

Feng, W.; Beer, J.; Hao, Q.; Ariyapala, I. S.; Sahajan, A.; Komarov, A.; Cha, K.; Moua, M.; Qiu, X.; Xu, X.; Iyengar, S.; Yoshimura, T.; Nagaraj, R.; Wang, L.; Yu, M.; Engel, K.; Zhen, L.; Xue, W.; Lee, C.-j.; Park, C. H.; Peng, C.; Zhang, K.; Grzybowski, A.; Hahm, J.; Schmidt, S. V.; Odainic, A.; Spitzer, J.; Bonn COVIMMUNE Consortium, ; Buddika, K.; Kuo, D.; Fang, L.; Zhang, B.; Chen, S.; Latz, E.; Yin, Y.; Luo, Y.; Ma, X.-J.

10.1101/2023.04.09.536130 — genomics — Posted on 2023-06-02

4217 COBRA improves the quality of viral genomes assembled from metagenomes

Chen, L.; Banfield, J. F.

10.1101/2023.05.30.542503 — genomics — Posted on 2023-06-02

4218 A Bayesian approach to Mendelian randomization using summary statistics in the univariable and multivariable settings with correlated pleiotropy

Grant, A. J.; Burgess, S.

10.1101/2023.05.30.542988 — genetics — Posted on 2023-06-02

4219 From GWAS to signal validation: An approach for estimating SNP genetic effects while preserving genomic context

Wolf, S.; Abhyankar, V.; Melo, D.; Ayroles, J. F.; Pallares, L. F.

10.1101/2023.03.09.531909 — genetics — Posted on 2023-06-02

4220 Viscous shear is a key force in Drosophila ventral furrow morphogenesis

Goldner, A. N.; Cheikh, M. I.; Osterfield, M.; Doubrovinski, K.

10.1101/2021.04.21.440835 — developmental biology — Posted on 2023-06-02

4221 Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis.

Wang, F.; Liu, X.; Huang, F.; Wang, W.; Zhou, Y.; Wang, X.; Song, Z.; Wang, S.; Wang, X.; Shi, D.; Ruan, G.; Ji, X.; Zhang, E.; Tan, Z.; Ye, Y.; Wang, C.; Zhu, J.

10.1101/2023.06.02.543432 — microbiology — Posted on 2023-06-02

4222 The basis of antigenic operon fragmentation in Bacteroidota and commensalism

Bank, N. C.; Singh, V.; Grubb, B.; McCourt, B.; Burberry, A.; Roberts, K. D.; Rodriguez-Palacios, A.

10.1101/2023.06.02.543472 — microbiology — Posted on 2023-06-02

4223 A shared neural code for the physics of actions and object events

Akbiyik, S.; Caramazza, A.; Wurm, M. F.

10.1101/2022.11.19.517091 — neuroscience — Posted on 2023-06-02

4224 Encoding of continuous perceptual choices in human early visual cortex

Barbieri, R.; Töpfer, F. M.; Soch, J.; Bogler, C.; Sprekeler, H.; Haynes, J.-D.

10.1101/2023.02.10.527876 — neuroscience — Posted on 2023-06-02

4225 Defined synthetic microbial communities colonize and benefit field-grown sorghum

Fonseca Garcia, C.; Wilson, A.; Elmore, J. R.; Pettinga, D.; McClure, R.; Atim, J.; Pedraza, J.; Hutmacher, R.; Egbert, R.; Coleman-Derr, D.

10.1101/2023.05.30.542977 — synthetic biology — Posted on 2023-06-02

4226 Elucidating the mechanism of microbial thermogenesis

Dhatt, P. S.; Moon, T. S.

10.1101/2023.06.02.543367 — synthetic biology — Posted on 2023-06-02

4227 Metagenomic Profiles of Archaea and Bacteria within Thermal and Geochemical Gradients of the Guaymas Basin Deep Subsurface

Geller-McGrath, D.; Mara, P.; Edgcomb, V. P.; Beaudoin, D.; Morono, Y.; Teske, A.

10.1101/2023.05.31.543050 — bioinformatics — Posted on 2023-06-02

4228 Quantifying uncertainty in off-target activity for CRISPR guide RNAs

Ozden, F.; Minary, P.

10.1101/2023.06.02.543468 — bioinformatics — Posted on 2023-06-02

4229 A Microfluidic Transistor for Liquid Signal Processing

Gopinathan, K. A.; Mishra, A.; Mutlu, B. R.; Edd, J. F.; Toner, M.

10.1101/2023.05.31.543146 — bioengineering — Posted on 2023-06-02

4230 Therapeutic TNF-alpha Delivery After CRISPR Receptor Modulation in the Intervertebral Disc

Stover, J. D.; Trone, M. A. R.; Weston, J.; Lewis, C.; Levis, H.; Philippi, M.; Zeidan, M.; Lawrence, B.; Bowles, R. D.

10.1101/2023.05.31.542947 — bioengineering — Posted on 2023-06-02

4231 Formation of amyloid fibrils by the regulatory 14-3-3ζ protein

Sulskis, D.; Ziaunys, M.; Sakalauskas, A.; Smirnovas, V.

10.1101/2023.05.31.543065 — biochemistry — Posted on 2023-06-02

4232 Rewiring protein binding specificity in paralogous DRG/DFRP complexes

Westrip, C. A. E.; Smerdon, S. J.; Coleman, M. L.

10.1101/2023.05.31.543024 — biochemistry — Posted on 2023-06-02

4233 Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry

Xie, Y. R.; Castro, D. C.; Rubakhin, S. S.; Sweedler, J. V.; Lam, F.

10.1101/2023.05.31.543144 — biochemistry — Posted on 2023-06-02

4234 Experimental and computational insights into the functional and structural role of the linker region of a two-domain lytic polysaccharide monooxygenase

Forsberg, Z.; Stepnov, A.; Tesei, G.; Wang, Y.; Buchinger, E.; Kristiansen, S. K.; Aachmann, F. L.; Arleth, L.; Eijsink, V. G. H.; Lindorff-Larsen, K.; Courtade, G.

10.1101/2023.06.01.543078 — biochemistry — Posted on 2023-06-02

4235 Characterisation of membrane protein interactions by peptidisc-mediated mass photometry

Young, J. W.; Pfitzner, E.; Kukura, P.; Robinson, C. V.

10.1101/2023.06.01.543083 — biochemistry — Posted on 2023-06-02

4236 A novel family of sugar-specific phosphodiesterases that remove zwitterionic modifications of N-acetylglucosamine

Fossa, S. L.; Anton, B. P.; Kneller, D. W.; Petralia, L. M. C.; Boisvert, M. L.; Vainauskas, S.; Hokke, C. H.; Foster, J. M.; Taron, C. H.

10.1101/2023.06.01.543256 — biochemistry — Posted on 2023-06-02

4237 Assessing the dynamics of Mycobacterium bovis infection in three French badger populations

Calenge, C.; Payne, A.; Reveillaud, E.; Richomme, C.; Girard, S.; Desvaux, S.

10.1101/2023.05.31.543041 — ecology — Posted on 2023-06-02

4238 Predication of the Post Mining Land Use Based on Random Forest and DBSCAN

Bo, Q.; Lv, P.; wang, Z.; wang, q.; li, z.

10.1101/2023.05.30.542990 — ecology — Posted on 2023-06-02

4239 Direct-print three-dimensional electrodes for large-scale, high-density, and customizable neural interfaces

Wang, P.; Wu, E. G.; Ulusan, H.; Phillips, A. J.; Hays, M. R.; Kling, A.; Zhao, E. T.; Madugula, S.; Vilkhu, R. S.; Vasireddy, P. K.; Hierlemann, A.; Hong, G.; Chichilnisky, E. J.; Melosh, N. A.

10.1101/2023.05.30.542925 — neuroscience — Posted on 2023-06-02

4240 Minimal condition repetitions required in rapid serial visual presentation decoding paradigms

Grootswagers, T.

10.1101/2023.05.30.542960 — neuroscience — Posted on 2023-06-02

4241 Enhancing gene co-expression network inference for the malaria parasite Plasmodium falciparum

Li, Q.; Button-Simons, K. A.; Sievert, M. A.; Chahoud, E.; Foster, G. F.; Meis, K.; Ferdig, M. T.; Milenkovic, T.

10.1101/2023.05.31.543171 — systems biology — Posted on 2023-06-02

4242 Impact of reference design on estimating SARS-CoV-2 lineage abundances from wastewater sequencing data

Assmann, E.; Agrawal, S.; Orschler, L.; Böttcher, S.; Lackner, S.; Hölzer, M.

10.1101/2023.06.02.543047 — bioinformatics — Posted on 2023-06-02

4243 Design Automation of Microfluidic Single and Double Emulsion Droplets with Machine Learning

Lashkaripour, A.; McIntyre, D. P.; Calhoun, S. G. K.; Krauth, K.; Densmore, D. M.; Fordyce, P. M.

10.1101/2023.05.31.543128 — bioengineering — Posted on 2023-06-02

4244 The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles

Ensinck, I.; Maman, A.; Albihlal, W.; Lassandro, M.; Salzano, G.; Sideri, T.; Howell, S.; Calvani, E.; Patel, H.; Bushkin, G. G.; Snijders, A. P.; Ralser, M.; Skehel, M.; Casanal, A.; Schwartz, S.; van Werven, F.

10.1101/2023.02.10.528004 — molecular biology — Posted on 2023-06-02

4245 Accumulation of defense systems in phage resistant strains of Pseudomonas aeruginosa

Costa, A. R.; van den Berg, D. F.; Esser, J. Q.; Muralidharan, A.; van den Bossche, H.; Estrada Bonilla, B.; van der Steen, B. A.; Haagsma, A. C.; Fluit, A. C.; Nobrega, F. L.; Haas, P.-J.; Brouns, S. J.

10.1101/2022.08.12.503731 — microbiology — Posted on 2023-06-02

4246 Decoding face recognition abilities in the human brain

Faghel-Soubeyrand, S.; Ramon, M.; Bamps, E.; Zoia, M.; Woodhams, J.; Richoz, A.-R.; Caldara, R.; Gosselin, F.; Charest, I.

10.1101/2022.03.19.484245 — neuroscience — Posted on 2023-06-02

4247 Sixteen oogenesin genes are dispensable for fertilityWhat is the significance of the dispensability of genes expressed in germ-cell?

Castille, J.; Thepot, D.; Fouchecourt, S.; Passet, B.; Daniel-Carlier, N.; Vilotte, J.-L.; Monget, P.

10.1101/2023.06.01.543189 — molecular biology — Posted on 2023-06-01

4248 Direct and indirect consequences of PAB1 deletion in the regulation of translation initiation, translation termination, and mRNA decay

Mangkalaphiban, K.; Ganesan, R.; Jacobson, A.

10.1101/2023.05.31.543082 — molecular biology — Posted on 2023-06-01

4249 Quantification of all 12 canonical ribonucleotides by real-time fluorogenic in vitro transcription

Purhonen, J.; Kallijarvi, J.

10.1101/2023.02.18.527797 — molecular biology — Posted on 2023-06-01

4250 Development of rapid and affordable virus-mimicking artificial positive controls

Singh, S.; Stainton, D.; Tzanetakis, I.

10.1101/2023.05.31.543123 — molecular biology — Posted on 2023-06-01

4251 minimap2-fpga: Integrating hardware-accelerated chaining for efficient end-to-end long-read sequence mapping

Liyanage, K.; Samarakoon, H.; Parameswaran, S.; Gamaarachchi, H.

10.1101/2023.05.30.542681 — bioinformatics — Posted on 2023-06-02

4252 Expansion of novel biosynthetic gene clusters from diverse environments using SanntiS

Sanchez Fragoso, J. S.; Rogers, J. D.; Rogers, A. B.; Nassar, M.; McEntyre, J.; Welch, M.; Hollfelder, F.; Finn, R. D.

10.1101/2023.05.23.540769 — bioinformatics — Posted on 2023-06-02

4253 Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase

Colin, L.; Reyes, C.; Berthezene, J.; Maestroni, L.; Modolo, L.; Toselli, E.; Chanard, N.; Schaak, S.; Cuvier, O.; Gachet, Y.; Coulon, S.; Bernard, P.; Tournier, S.

10.1101/2022.03.18.484892 — cell biology — Posted on 2023-06-02

4254 Atg15 is a vacuolar phospholipase that disintegrates organelle membranes

Watanabe, Y.; Iwasaki, Y.; Sasaki, K.; Suzuki, K.

10.1101/2023.05.31.543165 — molecular biology — Posted on 2023-06-01

4255 Short-term heat stress assays provide a standardized screening tool to assess impacts of microbiome manipulation on Aiptasia thermal stress tolerance

Doerr, M.; Denger, J.; Maier, C. S.; Kirsch, J. V.; Manns, H.; Voolstra, C. R.

10.1101/2023.06.01.543236 — microbiology — Posted on 2023-06-01

4256 Objects sharpen visual scene representations: evidence from MEG decoding

Brandman, T.; Peelen, M. V.

10.1101/2023.04.06.535903 — neuroscience — Posted on 2023-06-02

4257 Exoribonuclease RNase R protects Antarctic Pseudomonas syringae Lz4W from DNA damage and oxidative stress

Pavankumar, T. L.; Mittal, P.; Ray, M. K.; Sipani, R.; Sulthana, S.; Pandiyan, A.; Sinha, A. K.; Hussain, A.

10.1101/2023.06.01.543265 — microbiology — Posted on 2023-06-01

4258 The virulence regulator VirB from Shigella flexneri uses a CTP-dependent switch mechanism to activate gene expression

Jakob, S.; Steinchen, W.; Hanssmann, J.; Rosum, J.; Osorio-Valeriano, M.; Giammarinaro, P. I.; Bange, G.; Thanbichler, M.

10.1101/2023.06.01.543266 — microbiology — Posted on 2023-06-01

4259 Comprehensive locus-specific L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.

Lanciano, S.; Philippe, C.; Sarkar, A.; Pratella, D.; Domrane, C.; Doucet, A. J.; van Essen, D.; Saccani, S.; Ferry, L.; Defossez, P.-A.; Cristofari, G.

10.1101/2023.01.03.522582 — genomics — Posted on 2023-06-02

4260 NIRis: A low-cost, versatile imaging system for NIR fluorescence detection of phototrophic cell colonies used in science and education

Franz, O.; Häkkänen, H.; Kovanen, S.; Heikkilä-Huhta, K.; Nissinen, R.; Ihalainen, J. A.

10.1101/2023.05.31.543100 — microbiology — Posted on 2023-06-02

4261 Solvent based fractional biosynthesis, phytochemical analysis and biological activity of silver nanoparticles obtained from extract of Salvia moorcroftiana

Khan, M.; Khan, T.; Aasim, M.; Sherazi, T. A.; Wahab, S.; Zahoor, M.

10.1101/2023.05.30.542991 — microbiology — Posted on 2023-06-02

4262 Quality matters: stoichiometry of resources modulates spatial feedbacks in aquatic-terrestrial meta-ecosystems

Pichon, B.; Thebault, E.; Lacroix, G.; Gounand, I.

10.1101/2023.03.15.532732 — ecology — Posted on 2023-06-02

4263 Upregulated GRP78 and sFlt-1 in preeclampsia induces IRE1 and ATF6 arms of UPR leading to ER stress in placental cells

Mochan, S.; Gupta, S. K.; Arora, P.; Rani, N.; Dwivedi, S. N.; Bhatla, N.; Dhingra, R.

10.1101/2023.05.30.542817 — developmental biology — Posted on 2023-06-02

4264 Expression of RcrB confers resistance to hypochlorous acid in uropathogenic Escherichia coli

Crompton, M. E.; Gaessler, L. F.; Tawiah, P. O.; Polzer, L.; Camfield, S. K.; Johnson, C.; Meurer, K.; Bennis, M.; Roseberry, B.; Sultana, S.; Dahl, J.-U.

10.1101/2023.06.01.543251 — microbiology — Posted on 2023-06-01

4265 Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin

Xu, S.; MO, D.; Rizvi, F. Z.; Rosa, J.; Ruiz, J.; Tan, S.; Tweten, R. K.; Leong, J. M.; Adams, W.

10.1101/2023.06.01.543286 — microbiology — Posted on 2023-06-01

4266 Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans

Kellogg, C. M.; Pham, K.; Machalinski, A. H.; Porter, H. L.; Blankenship, H. E.; Tooley, K.; Stout, M. B.; Rice, H. C.; Sharpe, A. L.; Beckstead, M. J.; Elliott, A. J. C.; Ocanas, S. R.; Freeman, W. M.

10.1101/2023.03.07.531435 — neuroscience — Posted on 2023-06-02

4267 Dynamic allosteric networks drive adenosine A1 receptor activation and G-protein coupling

Maria Solano, M. A.; Choi, S.

10.1101/2022.08.08.502889 — biophysics — Posted on 2023-06-02

4268 Discovery of medicinal herbal compounds with potential anti-cancer activities against microtubule affinity-regulating kinase(MARK4) in cancer therapy

Narayanan, N.; K C, S.

10.1101/2023.05.30.542909 — bioinformatics — Posted on 2023-06-02

4269 Single-cell Electrochemical Aptasensor Array

Li, S.; Coffinier, Y.; Lagadec, C.; Cleri, F.; Nishiguchi, K.; Fujiwara, A.; Kim, S. H.; Clement, N.

10.1101/2023.03.16.532912 — bioengineering — Posted on 2023-06-02

4270 Reassessing the modularity of gene co-expression networks using the Stochastic Block Model

Melo, D.; Pallares, L. F.; Ayroles, J. F.

10.1101/2023.05.31.542906 — genomics — Posted on 2023-06-02

4271 Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1

Potter, B. d.; Raas, M. W. D.; Seidl, M. F.; Verrijzer, C. P.; Snel, B.

10.1101/2023.04.04.535607 — evolutionary biology — Posted on 2023-06-02

4272 Human-environment feedback and the consistency of proenvironmental behaviour

Ecotiere, C. D.; Billiard, S.; Andre, J.-B.; Collet, P.; Ferriere, R.; Meleard, S.

10.1101/2022.07.23.501219 — ecology — Posted on 2023-06-02

4273 TERRA R-loops connect and protect sister telomeres in mitosis

Sze, S.; Bhardwaj, A.; FNU, P.; Azarm, K.; Mund, R.; Ring, K.; smith, s.

10.1101/2023.05.31.543102 — cell biology — Posted on 2023-06-02

4274 Implications of differential size-scaling of cell-cycle regulators on cell size homeostasis

Ji, X.; Lin, J.

10.1101/2022.11.30.518453 — cell biology — Posted on 2023-06-02

4275 Ultra-conserved bacteriophage genome sequence identified in 1300-year-old human paleofaeces

Rozwalak, P.; Barylski, J.; Wijesekara, Y. R.; Dutilh, B. E.; Zielezinski, A.

10.1101/2023.06.01.543182 — microbiology — Posted on 2023-06-01

4276 Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

Gervasoni, S.; Mehla, J.; Bergen, C.; Leus, I. V.; Margiotta, E.; Malloci, G.; Bosin, A.; Vargiu, A. V.; Lomovskaya, O.; RYBENKOV, V.; Ruggerone, P.; Zgurskaya, H. I.

10.1101/2023.06.01.543207 — microbiology — Posted on 2023-06-01

4277 Epidermal Growth Factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated medium

Wang, P.; Zhou, R.; Zhou, R.; Yu, L.; Zhao, L.; Li, W.; Lin, J.; Rajapakse, A.; Lee, C.-H.; Furnari, F. B.; Burgess, A. W.; Gunter, J. H.; Liu, G.; Ostrikov, K.; Richard, D. J.; Simpson, F.; Dai, X.; Thompson, E.

10.1101/2023.05.30.542966 — cancer biology — Posted on 2023-06-02

4278 Spatial and temporal characterization of the rich fraction of plastid DNA present in the nuclear genome of Moringa oleifera reveals unanticipated complexity in NUPTs' formation

Marczuk-Rojas, J. P.; Alamo-Sierra, A. M.; Salmeron, A.; Alcayde, A.; Isanbaev, V.; Carretero-Paulet, L.

10.1101/2023.05.31.542793 — genomics — Posted on 2023-06-02

4279 Upregulation of the NKG2D ligand ULBP2 by JC polyomavirus infection promotes immune recognition by natural killer cells.

Jost, S.; Ahn, J.; Chen, S.; Yoder, T.; Gikundiro, K. E.; Lee, E.; Gressens, S. B.; Kroll, K.; Craemer, M.; Kaynor, G. C.; Lifton, M.; Tan, C. S.

10.1101/2023.05.31.543006 — immunology — Posted on 2023-06-02

4280 Hyperinsulinemia acts through acinar cell insulin receptors to drive obesity-associated pancreatic cancer initiation by promoting digestive enzyme production and inflammation

Zhang, A. M. Y.; Xia, Y. H.; Lin, J. S. H.; Chu, K. H.; Wang, W. C. K.; Ruiter, T. J. J.; Yang, J. C. C.; Chen, N.; Chhuor, J.; Patil, S.; Cen, H. H.; Rideout, E.; Richard, V. R.; Schaeffer, D. F.; Zahedi, R. P.; Borchers, C. H.; Johnson, J. D.; Kopp, J.

10.1101/2022.05.06.490845 — cancer biology — Posted on 2023-06-01

4281 Chromatin organization drives the exploration strategy of nuclear factors

Mazzocca, M.; Loffreda, A.; Colombo, E.; Fillot, T.; Gnani, D.; Falletta, P.; Monteleone, E.; Capozi, S.; Bertrand, E.; Legube, G.; Lavagnino, Z.; Tacchetti, C.; Mazza, D.

10.1101/2022.12.29.522193 — biophysics — Posted on 2023-06-01

4282 Genetic determinants of plasma protein levels in the Estonian population

Kalnapenkis, A.; Joeloo, M.; Lepik, K.; Kukuskina, V.; Kals, M.; Alasoo, K.; Mägi, R.; Esko, T.; Vosa, U.; Andres Metspalu, Lili Milani, Mari Nelis, Georgi Hudjashov,

10.1101/2023.05.30.542983 — genomics — Posted on 2023-06-02

4283 Dominant negative and directional dysregulation of Polycomb function in EZH2-mutant human growth disorders

Deevy, O.; Monger, C.; Matra, F.; Tuck, E.; Conway, E.; Rodighiero, S.; Zhang, Q.; Davidovich, C.; Pasini, D.; Bracken, A. P.

10.1101/2023.06.01.543208 — genetics — Posted on 2023-06-01

4284 Developmental Alterations in Brain Network Asymmetry in 3- to 9-Month Infants with Congenital Sensorineural Hearing Loss

Liu, G.; Zhou, X.; Hu, Z.; Liu, Y.; Huo, E.; Bortfeld, H.; Dong, Q.; Liu, H.; Niu, H.

10.1101/2023.05.31.543147 — neuroscience — Posted on 2023-06-01

4285 Deciphering Neuronal Deficit and Protein Profile Changes in Human Brain Organoids from Patients with Creatine Transporter Deficiency

10.1101/2023.06.01.543271 — neuroscience — Posted on 2023-06-01

4286 The Sponges of the Carmel Pinnacles Marine Protected Area

Turner, T. L.; Lonhart, S.

10.1101/2022.11.02.514922 — zoology — Posted on 2023-06-01

4287 Cell motility modes are selected by the interplay of mechanosensitive adhesion and membrane tension

Chen, Y.; Saintillan, D.; Rangamani, P.

10.1101/2023.05.31.543156 — biophysics — Posted on 2023-06-01

4288 Building flexible and robust analysis frameworks for molecular subtyping of cancers

Pedersen, C. B.; Campos, B.; Krishnan, N. M.; Panda, B.; Vitting-Seerup, K.; Rossing, M. C.; Bagger, F. O.; Olsen, L. R.

10.1101/2023.05.01.538907 — bioinformatics — Posted on 2023-06-01

4289 Discovery of medicinal herbal compounds with potential anti-cancer activities against microtubule affinity-regulating kinase(MARK4) in cancer therapy

Narayanan, N.

10.1101/2023.05.30.542909 — bioinformatics — Posted on 2023-06-01

4290 Beyond conflict: kinship theory of intragenomic conflict predicts individual variation in altruistic behavior

Bresnahan, S. T.; Galbraith, D.; Ma, R.; Anton, K.; Rangel, J.; Grozinger, C. M.

10.1101/2023.06.01.543237 — animal behavior and cognition — Posted on 2023-06-01

4291 Exome-wide analysis implicates rare protein-altering variants in human handedness

Schijven, D.; Soheili-Nezhad, S.; Fisher, S. E.; Francks, C.

10.1101/2023.05.31.543042 — genetics — Posted on 2023-06-01

4292 Evolution of the mutation spectrum across a mammalian phylogeny

Beichman, A. C.; Robinson, J. A.; Lin, M.; Moreno-Estrada, A.; Nigenda-Morales, S.; Harris, K.

10.1101/2023.05.31.543114 — evolutionary biology — Posted on 2023-06-01

4293 How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot

Sahoo, B.; Mou, Z.; Liu, W.; Dubyak, G.; Dai, X.

10.1101/2023.05.31.543175 — immunology — Posted on 2023-06-01

4294 Stem cell memory EBV-specific T cells control post-transplant lymphoproliferative disease and persist in vivo

Palianina, D.; Mietz, J.; Stuehler, C.; Arnold, B.; Bantug, G. R.; Münz, C.; Chijioke, O.; Khanna, N.

10.1101/2023.05.30.542809 — immunology — Posted on 2023-06-01

4295 Prenatal SARS-CoV-2 infection alters postpartum human milk-derived extracellular vesicles

Chutipongtanate, S.; Cetinkaya, H.; Zhang, X.; Kuhnell, D.; Benefield, D.; Haffey, W.; Wyder, M.; Patel, R.; Conrey, S. C.; Burrell, A. R.; Langevin, S.; Nommsen-Rivers, L.; Newburg, D. S.; Greis, K. D.; Staat, M. A.; Morrow, A. L.

10.1101/2023.06.01.543234 — systems biology — Posted on 2023-06-01

4296 Computational Assessment on Catalytic Activity of PET Hydrolase

Cruz, I. N.; Ramos, R. B.

10.1101/2023.05.30.542930 — bioinformatics — Posted on 2023-06-01

4297 Secundary Structure of Physicochemical Clustered Proteins

Cruz, I. N.

10.1101/2023.05.30.542924 — bioinformatics — Posted on 2023-06-01

4298 Regulatory roles of three-dimensional structures of chromatin domains

Li, K. Y.; Cao, Q.; Wang, H.; Leung, D. C. Y.; Yip, K. Y.

10.1101/2022.07.22.501196 — bioinformatics — Posted on 2023-06-01

4299 scReadSim: a single-cell RNA-seq and ATAC-seq read simulator

Yan, G.; Song, D.; Li, J. J.

10.1101/2022.05.29.493924 — bioinformatics — Posted on 2023-06-01

4300 The structure of the neurotoxin palytoxin determined by MicroED

Gillman, C.; Patel, K.; Unge, J.; Gonen, T.

10.1101/2023.03.31.535166 — biochemistry — Posted on 2023-06-01

4301 Optimization of RNA Pepper sensors for the detection of arbitrary RNA targets

Tang, A.; Afasizheva, A.; Cano, C.; Plath, K.; Black, D. L.; Franco, E.

10.1101/2023.06.01.543282 — biochemistry — Posted on 2023-06-01

4302 Multiple E3 ligases control tankyrase stability and function

Perrard, J.; Smith, S.

10.1101/2023.05.31.543093 — biochemistry — Posted on 2023-06-01

4303 The pan-epigenome of the symbiotic nitrogen fixing bacterium Sinorhizobium meliloti unravels unexpected variability of DNA-methylation profiles in closely related strains

Passeri, I.; Cangioli, L.; Fondi, M.; Mengoni, A.; Fagorzi, C.

10.1101/2023.05.31.542881 — genomics — Posted on 2023-06-01

4304 Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and systemically regulates longevity from serotonergic and GABAergic neurons

Lazaro-Pena, M.; Cornwell, A. B.; Diaz-Balzac, C. A.; Das, R.; Ward, Z. C.; Macoretta, N.; Thakar, J.; Samuelson, A.

10.1101/2023.01.11.523661 — genetics — Posted on 2023-06-01

4305 Cross-protein transfer learning substantially improves disease variant prediction

Jagota, M.; Ye, C.; Albors, C.; Rastogi, R.; Koehl, A.; Ioannidis, N.; Song, Y. S.

10.1101/2022.11.15.516532 — genetics — Posted on 2023-06-01

4306 Highly pathogenic avian influenza A virus (HPAIV) H5N1 infection in two European grey seals (Halichoerus grypus) with encephalitis.

Osterhaus, A.; Mirolo, M.; Harder, T.; Beer, M.; Pohlmann, A.; Ahrens, A.-K.; Kuehl, B.; Wohlsein, P.; Baumgartner, W.; Rubio-Garcia, A.; Morito, H.-L.; Kramer, K.; Rosenberger, T.; Meinfelder, U.; Ludlow, M.

10.1101/2023.05.30.542941 — ecology — Posted on 2023-06-01

4307 A high-content siRNA screen reveals new regulators of nuclear membrane stability

Gunn, A. L.; Yashchenko, A. I.; Hatch, E. L.

10.1101/2023.05.30.542944 — cell biology — Posted on 2023-06-01

4308 A detailed Molecular Network Map and Model of the NLRP3 Inflammasome

Krantz, M.; Eklund, D.; Särndahl, E.; Hedbrant, A.

10.1101/2023.05.31.543045 — immunology — Posted on 2023-06-01

4309 Peripheral death by neglect and limited clonal deletion during physiologic B lymphocyte development

Willett, M. J.; McNees, C.; Sharma, S.; Newen, A. M.; Pfannenstiel, D.; Moyer, T.; Stephany, D.; Douagi, I.; Wang, Q.; Mayer, C. T.

10.1101/2023.05.30.542923 — immunology — Posted on 2023-06-01

4310 Single-cell type analysis of wing premotor circuits in the ventral nerve cord of Drosophila melanogaster

Ehrhardt, E.; Whitehead, S. C.; Namiki, S.; Minegishi, R.; Siwanowicz, I.; Feng, K.; Otsuna, H.; FlyLight Project Team, ; Meissner, G. W.; Stern, D.; Truman, J.; Shepherd, D.; Dickinson, M. H.; Ito, K.; Dickson, B. J.; Cohen, I.; Card, G. M.; Korff, W.

10.1101/2023.05.31.542897 — neuroscience — Posted on 2023-06-01

4311 Dendritic excitability controls overdispersion

Friedenberger, Z.; Naud, R.

10.1101/2022.11.18.517108 — neuroscience — Posted on 2023-06-01

4312 Spinal control of locomotion before and after spinal cord injury

Danner, S. M.; Shepard, C. T.; Hainline, C.; Shevtsova, N. A.; Rybak, I. A.; Magnuson, D. S. K.

10.1101/2023.03.22.533794 — neuroscience — Posted on 2023-06-01

4313 SPARCS, a platform for genome-scale CRISPR screening for spatial cellular phenotypes

Schmacke, N. A.; Maedler, S. C.; Wallmann, G.; Metousis, A.; Berouti, M.; Harz, H.; Leonhardt, H.; Mann, M.; Hornung, V.

10.1101/2023.06.01.542416 — systems biology — Posted on 2023-06-01

4314 Nutritional redundancy in the human diet and its application in phenotype association studies

Wang, X.-W.; Hu, Y.; Menichetti, G.; Grodstein, F.; Bhupathiraju, S. N.; Sun, Q.; Zhang, X.; Hu, F.; Weiss, S. T.; Liu, Y.-Y.

10.1101/2021.02.04.429776 — systems biology — Posted on 2023-06-01

4315 Quantifying changes in individual-specific center-of-mass dynamics during walking with ankle exoskeletons using Hybrid-SINDy

Rosenberg, M. C.; Proctor, J. L.; Steele, K. M.

10.1101/2022.01.31.478514 — systems biology — Posted on 2023-06-01

4316 A spatially resolved EGFR signaling model predicts the length scale of GAB1-SHP2 complex persistence

Myers, P. J.; Furcht, C. M.; Pinilla-Macua, I.; Sorkin, A.; Deen, W. M.; Lazzara, M. J.

10.1101/2021.11.08.467801 — systems biology — Posted on 2023-06-01

4317 Spatial Organization of Gas Vesicles is Governed by Phase-separable GvpU

Li, Z.; Shen, Q.; Dai, Y.; Anderson, A. P.; Iburg, M.; Lin, R.; Zimmer, B.; Meyer, M. D.; You, L.; Chilkoti, A.; Lu, G. J.

10.1101/2023.06.01.543273 — synthetic biology — Posted on 2023-06-01

4318 Metagenomic domain substitution for the high-throughput modification of non-ribosomal peptide analogues

Messenger, S. R.; McGuinniety, E. M. R.; Stevenson, L. J.; Owen, J. G.; Challis, G. L.; Ackerley, D. F.; Calcott, M. J.

10.1101/2023.05.31.543161 — synthetic biology — Posted on 2023-06-01

4319 Immunity priming uncouples the growth-defense tradeoff in tomato

Leibman-Markus, M.; Schneider, A.; Gupta, R.; Marash, I.; Rav-David, D.; Carmeli-Weissberg, M.; Elad, Y.; Bar, M.

10.1101/2022.07.24.501304 — plant biology — Posted on 2023-06-01

4320 Cell wall pectic β-1,4-galactan contributes to increased plant freezing tolerance induced by cold acclimation

Takahashi, D.; Soga, K.; Sasaki, K.; Kikuchi, T.; Kutsuno, T.; Nishiyama, Y.; Johnson, K. L.; Sampathkumar, A.; Bacic, A.; Kotake, T.

10.1101/2023.05.31.542803 — plant biology — Posted on 2023-06-01

4321 Age and sex dependent effects of metabolic response to muscle contraction

Campbell, M. D.; Djukovic, D.; Raftery, D.; Marcinek, D.

10.1101/2023.05.30.542769 — physiology — Posted on 2023-06-01

4322 Discovering venom-derived drug candidates using differential gene expression

Romano, J. D.; Li, H.; Napolitano, T.; Realubit, R.; Karan, C.; Holford, M.; Tatonetti, N.

10.1101/699280 — pharmacology and toxicology — Posted on 2023-06-01

4323 Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL

Laprade, W. M.; Bartlett, K. E.; Christensen, C. R.; Kazandjian, T. D.; Patel, R. N.; Crittenden, E.; Dawson, C. A.; Mansourvar, M.; Wolff, D. S.; Fryer, T. J.; Laustsen, A. H.; Casewell, N. R.; Gutierrez, J. M.; Hall, S. R.; Jenkins, T. P.

10.1101/2023.05.21.541619 — pharmacology and toxicology — Posted on 2023-06-01

4324 Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

Issa, R.; Lozano, N.; Kostarelos, K.; Vranic, S.

10.1101/2023.03.30.534957 — pharmacology and toxicology — Posted on 2023-06-01

4325 Lyssa excreta: Defining parameters for fecal samples as a rabies virus surveillance method

Walker, F. M.; Upton, J. R.; Erickson, D.; Barrand, Z. A.; Brock, B.; Valentine, M.; Federman, E. L.; Froehlich, E. M.; Van Pelt, L. I.; Hastings, L.; Bergman, D. L.; Engelthaler, D. M.; Hepp, C. M.

10.1101/2023.05.27.542586 — pathology — Posted on 2023-06-01

4326 Serial KinderMiner (SKiM) Discovers and Annotates Biomedical Knowledge Using Co-Occurrence and Transformer Models

Millikin, R.; Raja, K.; Steill, J.; Lock, C.; Tu, X.; Ross, I.; Tsoi, L. C.; Kuusisto, F.; Ni, Z.; Livny, M.; Bockelman, B.; Thomson, J.; Stewart, R.

10.1101/2023.05.30.542911 — bioinformatics — Posted on 2023-06-01

4327 Identification of bioactive constituents for colitis from traditional Chinese medicine prescription via deep neural network

Ren, Z.; Ren, Y.; Liu, P.; Shu, Q.; Ma, H.; Xu, H.

10.1101/2023.05.31.542690 — bioinformatics — Posted on 2023-06-01

4328 EnCPdock: a web-interface for direct conjoint comparative analyses of complementarity and binding energetics in inter-protein associations

Biswas, G.; Mukherjee, D.; Dutta, N.; Ghosh, P.; Basu, S.

10.1101/2023.02.26.530084 — bioinformatics — Posted on 2023-06-01

4329 Effect of Aging, Sex, and Gene (Fbln5) on Arterial Stiffness of Mice: 20 Weeks Adult Fbln5-knockout Mice Have Older Arteries than 100 Weeks Wild-Type Mice

Dong, H.; Ferruzzi, J.; Liu, M.; Brewster, L. P.; Leshnower, B. G.; Gleason, R. L.

10.1101/2023.05.30.542920 — bioengineering — Posted on 2023-06-01

4330 Microstructured silk-fiber scaffolds with enhanced stretchability

Viola, M.; Cedillo-Servin, G.; van Genderen, A. M.; Imhof, I.; Vena, M. P.; Mihajlovic, M.; Piluso, S.; Malda, J.; Vermonden, T.; Castilho, M.

10.1101/2023.06.01.542724 — bioengineering — Posted on 2023-06-01

4331 Structure of puromycin-sensitive aminopeptidase and polyglutamine binding

Madabushi, S.; Chow, K. M.; Song, E. S.; Goswami, A.; Hersh, L. B.; Rodgers, D. W.

10.1101/2023.05.30.542994 — biochemistry — Posted on 2023-06-01

4332 Comparison of colorimetric, fluorometric, and liquid chromatography-mass spectrometry assays for acetyl-coenzyme A

Kantner, D. S.; Bostwick, A.; Yang, V.; Megill, E.; Bekeova, C.; Seifert, E.; Snyder, N. W.

10.1101/2023.06.01.543311 — biochemistry — Posted on 2023-06-01

4333 CRISPRi-TnSeq: A genome-wide high-throughput tool for bacterial essential-nonessential genetic interaction mapping

van Opijnen, T.; Jana, B.; Liu, X.; Denereaz, J.; Park, H.; Leshchiner, D.; Liu, B.; Gallay, C.; Veening, J.-W.

10.1101/2023.05.31.543074 — genetics — Posted on 2023-06-01

4334 Nuclear genetic diversity of head lice sheds light on human dispersal around the world

Ascunce, M. S.; Toloza, A. C.; Gonzalez-Oliver, A.; Reed, D. L.

10.1101/2022.08.09.503408 — evolutionary biology — Posted on 2023-06-01

4335 Cross population comparison of complex migration strategies in a declining oceanic seabird

O'Hanlon, N. J.; van Bemmelen, R. S. A.; Snell, K. R. S.; Conway, G. J.; Thaxter, C. B.; Aiton, H.; Aiton, D.; Balmer, D. E.; Hanssen, S. A.; Calladine, J. R.; Hammer, S.; Harris, S. J.; Moe, B.; Schekkerman, H.; Tulp, I.; Humphreys, E. M.

10.1101/2023.06.01.541278 — ecology — Posted on 2023-06-01

4336 A biologically realistic model to predict wildlife-vehicle collision risks

Benard, A.; Lengagne, T.; Bonenfant, C.

10.1101/2023.02.15.528614 — ecology — Posted on 2023-06-01

4337 The actin cytoskeleton plays multiple roles in structural color formation in butterfly wing scales

Lloyd, V. J.; Burg, S. L.; Harizanova, J.; Hill, O.; Enciso-Romero, J.; Cooper, R. L.; Flenner, S.; Longo, E.; Greving, I.; Nadeau, N. J.; Parnell, A. J.

10.1101/2023.06.01.542791 — developmental biology — Posted on 2023-06-01

4338 Separate Gut Plasma Cell Populations Produce Autoantibodies Against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis

Das, S.; Stamnaes, J.; Kemppainen, E.; Hervonen, K.; Lundin, K. E. A.; Parmar, N.; Jahnsen, F. L.; Jahnsen, J.; Lindfors, K.; Salmi, T.; Iversen, R.; Sollid, L. M.

10.1101/2023.05.31.542741 — immunology — Posted on 2023-06-01

4339 Odor modality is transmitted to cortical brain regions from the olfactory bulb

Craft, M. F.; Barreiro, A. K.; Hari Gautam, S.; Shew, W.; Ly, C.

10.1101/2023.02.26.530150 — neuroscience — Posted on 2023-06-01

4340 Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease

Ocanas, S. R.; Pham, K. D.; Cox, J. E. J.; Keck, A. W.; Ko, S.; Ampadu, F. A.; Porter, H. L.; Ansere, V. A.; Kulpa, A.; Kellogg, C. M.; Machalinski, A. H.; Chucair-Elliott, A. J.; Freeman, W. M.

10.1101/2023.03.07.531562 — neuroscience — Posted on 2023-06-01

4341 Single-cell analysis of innate spinal cord regeneration identifies intersecting modes of neuronal repair.

Muraleedharan Saraswathy, V.; Zhou, L.; Mokalled, M. H.

10.1101/2023.05.19.541505 — neuroscience — Posted on 2023-06-01

4342 Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia

Funes, S.; Gadd, D. H.; Mosqueda, M.; Zhong, J.; Jung, J.; FNU, S.; Unger, M.; Cameron, D.; Dawes, P.; Keagle, P. J.; McDonough, J. A.; Boopathy, S.; Sena-Esteves, M.; Lutz, C. M.; Skarnes, W. C.; Lim, E. T.; Schafer, D. P.; Massi, F.; Landers, J. E.; Bosco, D. A.

10.1101/2023.06.01.541136 — neuroscience — Posted on 2023-06-01

4343 BIN1 knockdown rescues systolic dysfunction in the aging heart

Westhoff, M.; del Villar, S. G.; Voelker, T. L.; Thai, P. N.; Chiamvimonvat, N.; Dickson, E. J.; Dixon, R. E.

10.1101/2022.08.23.504979 — physiology — Posted on 2023-06-01

4344 MFGE8 inhibits insulin signaling through PTP1B

Datta, R.; Podolsky, M. J.; Yang, C. D.; Alba, D.; Singh, S.; Koliwad, S.; Lizama, C. O.; Atabai, K.

10.1101/2023.05.30.542928 — physiology — Posted on 2023-06-01

4345 Identification of unique cytokine expressions in tumor immune microenvironment for various cancer types using single-cell RNA sequencing data via machine learning

Ren, Z.; Ren, Y.; Liu, P.; Xu, H.

10.1101/2023.06.01.542694 — bioinformatics — Posted on 2023-06-01

4346 ChimeraTE: A pipeline to detect chimeric transcripts derived from genes and transposable elements

Siqueira Oliveira, D.; Fablet, M.; Larue, A.; Vallier, A.; Aparecida Carareto, C.; Rebollo, R.; Vieira, C.

10.1101/2022.09.05.505575 — bioinformatics — Posted on 2023-06-01

4347 A Spatial Transcriptomics based Label-Free Method for Assessment of Human Stem Cell Distribution and Effects in a Mouse Model of Lung Fibrosis

Park, J.; Lee, D.; Lee, J. E.; Lee, D.; Song, I. H.; Park, H. S.; Choi, H.; Im, H.-J.

10.1101/2023.05.31.542821 — bioinformatics — Posted on 2023-06-01

4348 Large-scale column-free purification of bovine F-ATP synthase

Chimari, J.; Morimoto, Y.; Tsukihara, T.; Gerle, C.

10.1101/2023.06.01.543336 — biochemistry — Posted on 2023-06-01

4349 The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes

Dym, O.; Aggawal, N.; Ashani, Y.; Albeck, S.; Unger, T.; Hamer Rogotner, S.; Silman, I.; Tawfik, D. S.; Sussman, J. L.

10.1101/2023.05.31.542999 — biochemistry — Posted on 2023-06-01

4350 A TREX1 model reveals double-strand DNA preference and inter-protomer regulation

Hemphill, W. O.; Hollis, T.; Salsbury, F. R.; Perrino, F. W.

10.1101/2022.02.25.481063 — biochemistry — Posted on 2023-06-01

4351 Covalent targeting as a common mechanism for inhibiting NLRP3 inflammasome assembly.

Stanton, C.; Sun, J.; Nutsch, K.; Rosarda, J. D.; Nguyen, T.; Li-Ma, C.; Kutseikin, S.; Saez, E.; Teijaro, J. R.; Wiseman, L.; Bollong, M. J.

10.1101/2023.06.01.543248 — biochemistry — Posted on 2023-06-01

4352 Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex

Chen, M. H.; Ren, X.; Cook, A. S. I.; Hurley, J. H.

10.1101/2023.06.01.543278 — biochemistry — Posted on 2023-06-01

4353 Gene Expression and Physiological traits in Mice

Cruz, I. N.; Ramos, R. B.

10.1101/2023.05.30.542939 — genomics — Posted on 2023-06-01

4354 Transposons contribute to the functional diversification of the head, gut, and ovary transcriptomes across Drosophila natural strains

Coronado-Zamora, M.; Gonzalez, J.

10.1101/2022.12.02.518890 — evolutionary biology — Posted on 2023-06-01

4355 Dissecting genetic correlation through recombinant perturbations: the role of developmental bias

Cai, H.; Geiler-Samerotte, K.; Des Marais, D. L.

10.1101/2023.05.12.540583 — evolutionary biology — Posted on 2023-06-01

4356 Genomic patterns in the global soil microbiome emerge from microbial interactions

Crocker, K.; Chakraverti-Wuerthwein, M.; Li, Z.; Mani, M.; Gowda, K.; Kuehn, S.

10.1101/2023.05.31.542950 — ecology — Posted on 2023-06-01

4357 Agnostic fungi: plant functional types and tissue stoichiometry explain nutrient transfer in common arbuscular mycorrhizal networks of temperate grasslands

Dawson, H. R.; Shek, K. L.; Maxwell, T. M.; Reed, P. B.; Bomfim, B.; Bridgham, S.; Bohannan, B.; Silva, L. C. R.

10.1101/2022.10.05.511035 — ecology — Posted on 2023-06-01

4358 Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir.

Ribeiro, R.; Matthiopoulos, J.; Lindgren, F.; Tello, C.; Zariquiey, C. M.; Valderrama, W.; Rocke, T. E.; Streicker, D. G.

10.1101/2023.04.04.535562 — ecology — Posted on 2023-06-01

4359 Four novel Caudoviricetes bacteriophages isolated from Baltic Sea water infect colonizers of Aurelia aurita

Stante, M.; Weiland-Braeuer, N.; Repnik, U.; Werner, A.; Chibani, C. M.; Bramkamp, M.; Schmitz, R. A.

10.1101/2023.06.01.543199 — microbiology — Posted on 2023-06-01

4360 Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

Cao, X.; Xiao, Y.; Huiting, E.; Cao, X.; Li, D.; Ren, J.; Guan, L.; Wang, Y.; Li, L.; Bondy-Denomy, J.; Feng, Y.

10.1101/2023.06.01.543220 — microbiology — Posted on 2023-06-01

4361 Invasion of spontaneous germinal centers by naive B cells is rapid and persistent

van den Broek, T.; Oleinika, K.; Rahmayanti, S.; Castrillon, C.; van der Poel, C. E.; Carroll, M. C.

10.1101/2023.05.30.542805 — immunology — Posted on 2023-06-01

4362 Model-free decision making resists improved instructions and is enhanced by stimulus-response associations

Luna, R.; Vadillo, M. A.; Luque, D.

10.1101/2022.11.23.517672 — neuroscience — Posted on 2023-06-01

4363 A transthalamic pathway crucial for perception

Mo, C.; McKinnon, C.; Makitani, M.; Sherman, S. M.

10.1101/2023.03.30.533323 — neuroscience — Posted on 2023-06-01

4364 Increased presynaptic excitability in a migraine with aura mutation

Suryavanshi, P.; Sawant-Pokam, P.; Clair, S.; Brennan, K.

10.1101/719039 — neuroscience — Posted on 2023-06-01

4365 Microglia undergo rapid phenotypic transformation in acute brain slices but remain essential for neuronal synchrony

Berki, P.; Cserep, C.; Posfai, B.; Szabadits, E.; Kornyei, Z.; Kellermayer, A.; Nyerges, M.; Xiaofei, W.; Mody, I.; Kunihiko, A.; Heinz, B.; Kaikai, H.; Ya, W.; Wu, Z.; Jing, M.; Li, Y.; Gulyas, A. I.; Denes, A.

10.1101/2022.04.12.487998 — neuroscience — Posted on 2023-06-01

4366 Cross-Modal Representation of Identity in Primate Hippocampus

Tyree, T.; Metke, M.; Miller, C.

10.1101/2022.09.12.507611 — neuroscience — Posted on 2023-06-01

4367 Foveal RGCs develop abnormal calcium dynamics weeks after photoreceptor ablation

Xu, Z.; Kunala, K.; Murphy, P.; Puthussery, T.; McGregor, J. E.

10.1101/2023.05.30.542908 — physiology — Posted on 2023-06-01

4368 Circulating neutrophils from patients with early breast cancer have distinct subtype-dependent phenotypes

Ramessur, A.; Ambasager, B.; Aramburu, I. V.; Peakman, F.; Gleason, K.; Lehmann, C.; Papayannopoulos, V.; Coombes, C.; Malanchi, I.

10.1101/2023.04.19.537022 — cancer biology — Posted on 2023-06-01

4369 Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants

Hinterding, H.; Baghdadi, M.; Gehrmann, T.; Putter, P.; Lakenberg, N.; van den Akker, E. B.; Slagboom, P. E.; Deelen, J.; Partridge, L.

10.1101/2023.06.01.541708 — genetics — Posted on 2023-06-01

4370 A furin-deficient HEK293 cell line suggests a role for furin trafficking in the intoxication pathway of recombinant immunotoxins based on Pseudomonas exotoxin A

Grossman, B. D.; Sanford, J. D.; Zhu, Y.; Zeller, C. B.; Weldon, J. E.

10.1101/2023.05.31.542721 — molecular biology — Posted on 2023-06-01

4371 Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice

Ullah, I.; Escudie, F.; Scandale, I.; Gilani, Z.; Gendron-Lepage, G.; Gaudette, F.; Mowbray, C.; Fraisse, L.; Bazin, R.; Finzi, A.; Mothes, W.; Kumar, P.; Chatelain, E.; Uchil, P. D.

10.1101/2023.05.31.543159 — microbiology — Posted on 2023-06-01

4372 A Novel Amino Acid Deletion and Substitution in amrB Gene Associated with Gentamicin Susceptibility in Burkholderia pseudomallei from Malaysian Borneo

Hussin, A.; Nathan, S.; Shahidan, M. A.; Nor Rahim, M. Y.; Zainun, M. Y.; Khairuddin, N. A. N.; Ibrahim, N.

10.1101/2023.05.31.543095 — microbiology — Posted on 2023-06-01

4373 Functional Genomics of Gastrointestinal Escherichia coli Isolated from Patients with Cancer and Diarrhea

Carter, H.; Clark, J.; Carlin, L. G.; Vaughan, E.; Rajan, A.; Olvera, A.; Yu, X.; Zeng, X.-L.; Kambal, A.; Holder, M.; Qin, X.; Gibbs, R. A.; Petrosino, J. F.; Muzny, D. M.; Doddapaneni, H.; Menon, V. K.; Hoffman, K. L.; Meng, Q.; Ross, M. C.; Javornik Cregeen, S. J.; Metcalf, G.; Jenq, R.; Blutt, S.; Estes, M. K.; TMC-GCID team, ; Maresso, A. W.; Okhuysen, P. C.

10.1101/2023.05.31.543115 — microbiology — Posted on 2023-06-01

4374 Reference-free multiplexed single-cell sequencing identifies genetic modifiers of the human immune response

Hartoularos, G. C.; Si, Y.; Zhang, F. C.; Kathail, P.; Lee, D.; Ogorodnikov, A.; Sun, Y.; Song, Y. S.; Kang, H. M.; Ye, C. J.

10.1101/2023.05.29.542756 — genomics — Posted on 2023-06-01

4375 Opposing implications of co-evolutionary lineages and traits of gut microbiome on human health status

Li, H.; He, J.; Liang, J.; Liang, Y.; Zheng, W.; Qu, Q.; Guo, F.

10.1101/2023.05.30.542569 — microbiology — Posted on 2023-06-01

4376 Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum

Gray, J.; Torres, V. V. L.; Goodall, E. C.; Dunne, K.; Icke, C.; Rooke, J.; Schneiders, T.; Cunningham, A. F.; Cole, J. A.; Henderson, I. R.

10.1101/2023.05.31.543172 — microbiology — Posted on 2023-06-01

4377 The road to restoration: Identifying and conserving the adaptive legacy of American chestnut

Sandercock, A. M.; Westbrook, J. W.; Zhang, Q.; Holliday, J. A.

10.1101/2023.05.30.542850 — genomics — Posted on 2023-06-01

4378 KDM3A and KDM3B Maintain Naive Pluripotency Through the Regulation of Alternative Splicing

Dillingham, C. M.; Cormaty, H.; Morgan, E.; Esgdaille, D.; Boutz, P.; Sridharan, R.

10.1101/2023.05.31.543088 — cell biology — Posted on 2023-06-01

4379 PERK-mediated antioxidant response is key for pathogen persistence in ticks

Rosche, K. L.; Hurtado, J.; Fisk, E. A.; Vosbigian, K. A.; Warren, A. L.; Sidak-Loftis, L. C.; Wright, S. J.; Ramirez-Zepp, E.; Park, J. M.; Shaw, D. K.

10.1101/2023.05.30.542958 — microbiology — Posted on 2023-06-01

4380 Culturable approach to rice-root associated bacteria in Burkina Faso: diversity, plant growth-promoting rhizobacteria properties and cross-comparison with metabarcoding data.

Sondo, M.; Wonni, I.; Koïta, K.; Rimbault, I.; Barro, M.; Tollenaere, C.; Moulin, L.; Klonowska, A.

10.1101/2023.05.30.542993 — microbiology — Posted on 2023-06-01

4381 Co-enrichment of cancer-associated bacterial taxa is correlated with immune cell infiltrates in esophageal tumor tissue

Greathouse, K. L.; Stone, J. K.; Vargas, A. J.; Choudhury, A.; Padgett, N.; White, J. R.; Jung, A.; Harris, C. C.

10.1101/2023.05.29.542596 — cancer biology — Posted on 2023-06-01

4382 DGKepsilon is S-palmitoylated at the cysteine located at the cytoplasmic end of its N-terminal transmembrane fragment

Traczyk, G.; Hromada-Judycka, A.; Swiatkowska, A.; Wisniewska, J.; Kwiatkowska, K.

10.1101/2023.06.01.543214 — cell biology — Posted on 2023-06-01

4383 Frictiotaxis underlies adhesion-independent durotaxis

Shellard, A.; Hampshire, P.; Stillman, N.; Dix, C.; Thorogate, R.; Imbert, A.; Charras, G.; Alert, R.; Mayor, R.

10.1101/2023.06.01.543217 — cell biology — Posted on 2023-06-01

4384 In vivo evolution of a Klebsiella pneumoniae capsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection

Bain, W.; Ahn, B.; Penaloza, H.; McElheny, C.; Tolman, N.; van der Geest, R.; Gonzalez-Ferrer, S.; Chen, N.; An, X.; Hosuru, R.; Tabary, M.; Papke, E.; Kohli, N.; Farooq, N.; Bachman, W.; Olonisakin, T.; Xiong, Z.; Griffith, M. P.; Sullivan, M.; Franks, J.; Mustapha, M.; Iovleva, A.; Suber, T.; Shanks, R. M.; Ferreira, V.; Stolz, D. B.; Van Tyne, D.; Doi, Y.; Lee, J.

10.1101/2023.05.31.542722 — microbiology — Posted on 2023-06-01

4385 Alcohol inhibits sociability via serotonin inputs to the nucleus accumbens

Wang, R.; Khan, K. M.; Balasubramanian, N.; James, T.; Pushpavathi, S. G.; Kim, D.; Pierson, S.; Wu, Q.; Niciu, M. J.; Hefti, M. M.; Marcinkiewcz, C. A.

10.1101/2023.05.29.542761 — neuroscience — Posted on 2023-06-01

4386 The lipid phosphatase activity of PTEN dampens FRA1 expression via AKT/mTOR signaling to suppress melanoma

Xu, X.; Bok, I.; Jasani, N.; Wang, K.; Chadourne, M.; Deng, O.; Welsh, E. A.; Kinose, F.; Rix, U.; Karreth, F. A.

10.1101/2023.06.01.543131 — cancer biology — Posted on 2023-06-01

4387 MCAK Inhibitors Induce Aneuploidy in Triple Negative Breast Cancer Models

Smith, J. C.; Husted, S.; Pilrose, J.; Ems-McClung, S. C.; Stout, J. R.; Carpenter, R. L.; Walczak, C. E.

10.1101/2023.05.31.543118 — cancer biology — Posted on 2023-06-01

4388 Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins

Odell, J. D.; Gräf, R.; Lammerding, J.

10.1101/2023.05.31.543154 — cell biology — Posted on 2023-06-01

4389 Rim aperture of autophagic membranesbalances cargo inclusion with vesicle maturation

Shatz, O.; Fraiberg, M.; Polyansky, A.; Shimoni, E.; Wolf, S. G.; Elazar, Z.

10.1101/2023.06.01.543228 — cell biology — Posted on 2023-06-01

4390 Study design features that improve effect sizes in cross-sectional and longitudinal brain-wide association studies

Kang, K.; Seidlitz, J.; Bethlehem, R. A. I.; Schildcrout, J.; Tao, R.; Xiong, J.; Jones, M. T.; Lifespan Brain Chart Consortium, ; 3R-BRAIN, ; AIBL, ; Alzheimers Disease Neuroimaging Initiative, ; Alzheimers Disease Repository Without Borders Investigators, ; CALM Team, ; CCNP, ; COBRE, ; cVEDA, ; Harvard Aging Brain Study, ; IMAGEN, ; POND, ; The PREVENT-AD Research Group, ; Alexander-Bloch, A.; Vandekar, S.

10.1101/2023.05.29.542742 — neuroscience — Posted on 2023-06-01

4391 Investigating individual variability in microstructural-functional coupling in the human cortex

Patel, R.; Dai, A.; Valk, S. L.; Desrosiers-Gregoire, G.; Devenyi, G. A.; Chakravarty, M. M.

10.1101/2023.05.29.542730 — neuroscience — Posted on 2023-06-01

4392 Nf1 Deficiency Increases Mammary Collagen Deposition and Restricts Adipocyte Differentiation Before Tumor Formation

Arumugam, M.; Tovar, E. A.; Essenburg, C. J.; Dischinger, P. S.; Beddows, I. T.; Wolfrum, E.; Madaj, Z. B.; Turner, L.; Feenstra, K.; Gallik, K. L.; Cohen, L.; Nichols, M.; Sheridan, R. T.; Esquibel, C. R.; Mouneimne, G.; Graveel, C. R.; Steensma, M. R.

10.1101/2023.06.01.539442 — cancer biology — Posted on 2023-06-01

4393 The lipid flippase ATP10B enables cellular lipid uptake under stress conditions

Wouters, R.; Beletchi, I.; Van den Haute, C.; Baekelandt, V.; Martin, S.; Eggermont, J.; Vangheluwe, P.

10.1101/2023.06.01.543059 — cell biology — Posted on 2023-06-01

4394 TANGO-Light - optogenetic control of transcriptional modulators

Przybyszewska-Podstawka, A.; Kalafut, J.; Czapinski, J.; Ngo, T. H.; Czerwonka, A.; Rivero-Muller, A.

10.1101/2023.05.31.543150 — cell biology — Posted on 2023-06-01

4395 The HLA-II immunopeptidome of SARS-CoV-2

Weingarten-Gabbay, S.; Chen, D.-Y.; Sarkizova, S.; Taylor, H. B.; Gentili, M.; Pearlman, L. R.; Bauer, M. R.; Rice, C. M.; Clauser, K. R.; Hacohen, N.; Carr, S. A.; Abelin, J. G.; Saeed, M.; Sabeti, P. C.

10.1101/2023.05.26.542482 — microbiology — Posted on 2023-06-01

4396 Rice biological nitrification inhibition efficiency depends on plant genotype exudation rate

Kaur-Bhambra, J.; Ebenezer Rajakulendran, J.; Bodington, D.; Jaspars, M.; Gubry-Rangin, C.

10.1101/2023.05.31.543046 — microbiology — Posted on 2023-06-01

4397 Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism

Harris, B.; Singh, D. K.; Verma, M.; Fahl, S. P.; Rhodes, M.; Sprinkle, S. R.; Wang, M.; Zhang, Y.; Perrigoue, J.; Kessel, R.; Peri, S.; West, J.; Giricz, O.; Boultwood, J.; Pellagatti, A.; Ramesh, K.; Montangna, C.; Pradhan, K.; Tyner, J.; Kennedy, B. K.; Holinstat, M.; Steidl, U.; Sykes, S.; Verma, A.; Wiest, D. L.

10.1101/2023.05.31.543132 — cancer biology — Posted on 2023-06-01

4398 Abnormality Detection for Medical Images UsingSelf-Supervision and Negative Samples

Rafiee, N.; gholamipoorfard, R.; Kollmann, M.

10.1101/2023.05.29.542748 — bioinformatics — Posted on 2023-06-01

4399 Single-cell multi-omic topic embedding reveals cell-type-specific and COVID-19 severity-related immune signatures

Zhou, M.; Zhang, H.; Bai, Z.; Mann-Krzisnik, D.; Wang, F.; Li, Y.

10.1101/2023.01.31.526312 — bioinformatics — Posted on 2023-06-01

4400 CXCR4 signaling strength regulates hematopoietic multipotent progenitor fate through extrinsic and intrinsic mechanisms

Rondeau, V.; Kalogeraki, M.; Roland, L.; Nader, Z. A.; Gourhand, V.; Bonaud, A.; Lemos, J.; Khamyath, M.; Moulin, C.; Schell, B.; Delord, M.; Bidaut, G.; Lecourt, S.; Freitas, C.; Anginot, A.; Mazure, N.; McDermott, D. H.; Parietti, V.; Setterblad, N.; Dulphy, N.; Bachelerie, F.; Aurrand-Lions, M.; Stockholm, D.; Lobry, C.; Murphy, P. M.; Espeli, M.; Mancini, S. J.; Balabanian, K.

10.1101/2023.05.31.542899 — cell biology — Posted on 2023-06-01

4401 Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism

Ghanaeian, A.; Majhi, S.; McCafferty, C. L.; Nami, B.; Black, C. S.; Yang, S. K.; Legal, T.; Papoulas, O.; Janowska, M.; Valente-Paterno, M.; Marcotte, E. M.; Wloga, D.; Bui, K. H.

10.1101/2023.05.31.543107 — cell biology — Posted on 2023-06-01

4402 Ultrastructural analysis reveals mitochondrial placement independent of synapse placement in fine caliber C. elegans neurons

Riboul, D. V.; Crill, S.; Oliva, C. D.; Restifo, M. G.; Joseph, R.; Joseph, K.; Nguyen, K. C.; Hall, D. H.; Fily, Y.; Macleod, G. T.

10.1101/2023.05.30.542959 — neuroscience — Posted on 2023-06-01

4403 Associative memory neurons of encoding multi-modal signals are recruited by neuroligin-3 mediated new synapse formation

Xu, Y.; Cui, T.; Li, J.; Chen, B.; Wang, J.-H.

10.1101/2023.06.01.543188 — neuroscience — Posted on 2023-06-01

4404 Angiogenic Steroids Induce Pathologic Scarring in a Preclinical Swine Model Via Dysfunctional Extracellular Matrix Deposition.

Reiche, E.; Keller, P. R.; Soares, V.; Schuster, C. R.; Mroueh, J.; Mroueh, V.; Tan, Y.; Kim, S. Y.; Billaud, M.; Newell-Fugate, A. E.; Lian, C. G.; O'Brien-Coon, D.

10.1101/2023.05.29.542765 — systems biology — Posted on 2023-06-01

4405 OICNet: A Neural Network for Online EEG Source Separation using Independent Component Analysis

Yeh, P.-T.; Tsai, A. C.; Hsieh, C.-Y.; Yang, C.-C.; Wei, C.-S.

10.1101/2023.05.29.542778 — bioinformatics — Posted on 2023-06-01

4406 Decoding fMRI Data: A Comparison Between Support Vector Machines and Deep Neural Networks

Liang, Y.; Bo, K.; Meyyappan, S.; Ding, M.

10.1101/2023.05.30.542882 — bioinformatics — Posted on 2023-06-01

4407 A TOPBP1 Allele Causing Male Infertility Uncouples XY Silencing Dynamics From Sex Body Formation

Ascencao, C. F. R.; Sims, J.; Dziubek, A.; Comstock, W.; Fogarty, E. A.; Badar, J.; Freire, R.; Grimson, A.; Weiss, R. S.; Cohen, P. E.; Smolka, M. B.

10.1101/2023.05.31.543071 — cell biology — Posted on 2023-06-01

4408 Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

Pardo-Lorente, N.; Gkanogiannis, A.; Cozzuto, L.; Ganez Zapater, A.; Espinar, L.; Garcia-Lopez, L.; Aydin, R. G.; Darai, E.; Severino, J.; Batlle-Morera, L.; Ponomarenko, J.; Sdelci, S.

10.1101/2023.06.01.543193 — cell biology — Posted on 2023-06-01

4409 Single-cell type analysis of wing premotor circuits in the ventral nerve cord of Drosophila melanogaster

10.1101/2023.05.31.542897 — neuroscience — Posted on 2023-06-01

4410 Sleep and memory consolidation are linked by RNA processing genes in the Drosophila mushroom body

Li, Y.; Chouhan, N. S.; Zhang, S. L.; Moore, R. S.; Shon, J.; Yue, Z.; Sehgal, A.

10.1101/2023.05.31.543136 — neuroscience — Posted on 2023-06-01

4411 Modulation of antigen discrimination by duration of immune contacts in a kinetic proofreading model of T cell activation with extreme statistics.

Morgan, J.; Lindsay, A.

10.1101/2023.05.30.542789 — systems biology — Posted on 2023-06-01

4412 Assessment of Blighia sapida on Cholinergic and Antioxidant Enzymes; Possible Use of the Plant Stem-Bark Extract as a Biological Pest Controlling Agent

Oriyomi, O. V.; Adekola, M. B.

10.1101/2023.05.30.542835 — plant biology — Posted on 2023-06-01

4413 Multi-target genome editing reduces polyphenol oxidase activity in wheat (Triticum aestivum L.) grains

Wold-McGimsey, F.; Krosch, C.; Alarcon Reverte, R.; Ravet, K.; Katz, A.; Stromberger, J.; Mason, E.; Pearce, S.

10.1101/2023.05.30.542859 — plant biology — Posted on 2023-06-01

4414 17α-estradiol Alleviates High-Fat Diet-Induced Inflammatory and Metabolic Dysfunction in Skeletal Muscle of Male and Female Mice

10.1101/2023.05.30.542870 — physiology — Posted on 2023-06-01

4415 Visualizing scRNA-Seq Data at Population Scale with GloScope

Wang, H.; Torous, W.; Gong, B.; Purdom, E.

10.1101/2023.05.29.542786 — bioinformatics — Posted on 2023-06-01

4416 Consensus peaks of chromatin accessibility in the human genome

Meng, Q.; Wu, X.; Li, C.; Li, J.; Xi, X.; Chen, S.; Jiang, R.; Wei, L.; Zhang, X.

10.1101/2023.05.30.542889 — bioinformatics — Posted on 2023-06-01

4417 Colonial ground nesting by Archaeopteryx suggests wing evolution in primal association with nesting and the ground up evolution of flight

Guimaraes, M. J.

10.1101/2023.05.30.542892 — evolutionary biology — Posted on 2023-06-01

4418 Milti-Scale Detrended Partial Cross-Correlation Analysis of Tree Ring Width and Climate Variations: Revealing Heat and Drought Stress Resilience Factors in a Forest Ecosystem

Bogachev, M. I.; Gafurov, A. M.; Iskandirov, P. Y.; Kaplun, D. I.; Kayumov, A. R.; Lyanova, A. I.; Pyko, N. S.; Pyko, S. A.; Safonova, A. N.; Sinitca, A. M.; Usmanov, B. M.; Tishin, D. V.

10.1101/2023.05.30.542825 — ecology — Posted on 2023-06-01

4419 Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

Pang, L.-Y.; DeLuca, S.; Zhu, H.; Urban, J.; Spradling, A. C.

10.1101/2023.05.31.543160 — developmental biology — Posted on 2023-06-01

4420 Detection and characterization of novel luchacoviruses, genus Alphacoronavirus, in meso-carnivores in the northeastern United States

Olarte-Castillo, X. A.; Plimpton, L. D.; McQueary, H. C.; Sun, Y.; Yu, Y. T.; Cover, S. C.; Richardson, A. N.; Grenier, J. K.; Cummings, K. J.; Bunting, E. M.; Diuk-Wasser, M.; Needle, D.; Schuler, K.; Stanhope, M. J.; Whittaker, G.; Goodman, L. B.

10.1101/2023.05.31.541188 — microbiology — Posted on 2023-06-01

4421 Albumin-binding recombinant human IL-18BP ameliorates macrophage activation syndrome and atopic dermatitis via direct IL-18 inactivation

Jang, Y.-S.; Lee, K.; Park, M.; Park, J. J.; Choi, G. M.; Kim, C.; Dehkohneh, S. B.; Chi, S.; Han, J.; Song, M. Y.; Han, Y.-H.; Cha, S.-H.; Kang, S. G.

10.1101/2023.05.30.542831 — immunology — Posted on 2023-06-01

4422 Microstructural dynamics of motor learning and sleep-dependent consolidation: a diffusion imaging study

Stee, W.; Legouhy, A.; Guerreri, M.; Villemonteix, T.; Zhang, H.; Peigneux, P.

10.1101/2023.05.30.542891 — neuroscience — Posted on 2023-06-01

4423 Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath

Butruille, L.; Jubin, P.; Martin, E.; Aigrot, M.-S.; Lhomme, M.; Fini, J.-B.; Demeneix, B.; Stankoff, B.; Lubetzki, C.; Zalc, B.; Remaud, S.

10.1101/2023.05.30.542807 — pharmacology and toxicology — Posted on 2023-06-01

4424 GIMLET: A Unified Graph-Text Model for Instruction-Based Molecule Zero-Shot Learning

Zhao, H.; Liu, S.; Ma, C.; Xu, H.; Fu, J.; Deng, Z.-H.; Kong, L.; Liu, Q.

10.1101/2023.05.30.542904 — bioinformatics — Posted on 2023-06-01

4425 RAMZIS: a bioinformatic toolkit for rigorous assessment of the alterations to glycoprotein structure that occur during biological processes

Hackett, W. E.; Chang, D.; Carvalho, L.; Zaia, J.

10.1101/2023.05.30.542895 — bioinformatics — Posted on 2023-06-01

4426 Efficient multi-fidelity computation of blood coagulation under flow

Guerrero-Hurtado, M.; Garcia-Villalba, M.; Gonzalo, A.; Martinez-Legazpi, P.; Kahn, A. M.; McVeigh, E.; Bermejo, J.; del Alamo, J. C.; Flores, O.

10.1101/2023.05.29.542763 — bioengineering — Posted on 2023-06-01

4427 Miniaturized CAR knocked onto CD3epsilon extends TCR function with CAR specificity under control of endogenous TCR signaling cascade

Manske, K.; Dressler, L.; Fraessle, S. P.; Effenberger, M.; Tschulik, C.; Cletiu, V.; Benke, E.; Wagner, M.; Schober, K.; Mueller, T. R.; Busch, D. H.; Stemberger, C.; Germeroth, L.; Poltorak, M. P.

10.1101/2023.05.30.542829 — bioengineering — Posted on 2023-06-01

4428 An ethogram method for the analysis of human distress in the aftermath of public conflicts

Pallante, V.; Ejbye-Ernst, P.; Rosenkrantz Lindegaard, M.

10.1101/2023.05.30.542823 — animal behavior and cognition — Posted on 2023-06-01

4429 Restoring declining species through translocations: A test case using flightless grasshoppers in an urban setting

Yagui Briones, H.; Hoffmann, A. A.; Kearney, M. R.

10.1101/2023.05.29.542782 — ecology — Posted on 2023-06-01

4430 Closed ecosystems extract energy through self-organized nutrient cycles

Goyal, A.; Flamholz, A. I.; Petroff, A. P.; Murugan, A.

10.1101/2023.05.30.542875 — ecology — Posted on 2023-06-01

4431 Soil intake modifies the gut microbiota and alleviates ovalbumin-induced mice asthma inflammation

Li, M.; Li, N.; Dong, Y.; Zhang, H.; Bai, Z.; Zhang, R.; Fei, Z.; Zhu, W.; Xiao, P.; Xiao, S.; Zhou, D.

10.1101/2023.05.31.543010 — microbiology — Posted on 2023-06-01

4432 Invasion of spontaneous germinal centers by naive B cells is rapid and persistent

van den Broek, T.; Oleinika, K.; Rahmayanti, S.; Castrillon, C.; van der Poel, C. E.; Carroll, M. C.

10.1101/2023.05.30.542805 — immunology — Posted on 2023-06-01

4433 A comparison of the binding sites of antibodies and single-domain antibodies

Gordon, G. L.; Capel, H. L.; Guloglu, B.; Richardson, E.; Stafford, R. L.; Deane, C. M.

10.1101/2023.05.30.542890 — immunology — Posted on 2023-06-01

4434 Lysine 117 on ataxin-3 modulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3

Blount, J. R.; Patel, N. C.; Libohova, K.; Harris, A. L.; Tsou, W.-L.; Sujkowski, A.; Todi, S. V.

10.1101/2023.05.30.542896 — neuroscience — Posted on 2023-06-01

4435 Combinatorial chloride and calcium channelopathy in myotonic dystrophy

Cisco, L. A.; Sipple, M. T.; Edwards, K. M.; Thornton, C. A.; Lueck, J. D.

10.1101/2023.05.29.542752 — physiology — Posted on 2023-06-01

4436 Coupling of renal sodium and calcium transport: A modeling analysis

Hakimi, S.; Dutta, P.; Layton, A.

10.1101/2023.05.29.542749 — physiology — Posted on 2023-06-01

4437 Genomic diversity of wild and cultured Yesso scallop Mizuhopecten yessoensis from Japan and Canada

Sutherland, B. J. G.; Itoh, N.; Gilchrist, K.; Boyle, B.; Roth, M.; Green, T. J.

10.1101/2023.05.31.540437 — genomics — Posted on 2023-06-01

4438 COBRA improves the quality of viral genomes assembled from metagenomes

Chen, L.; Banfield, J. F.

10.1101/2023.05.30.542503 — genomics — Posted on 2023-06-01

4439 Progress toward the development of an effective vaccine for Extraintestinal pathogenic E. coli (ExPEC): The application of the multiple-protein subunits vaccine in different murine models

Xing, Y.; Clark, J. R.; Chang, J. D.; Zulk, J. J.; Chirman, D. M.; Piedra, F.-A.; Patras, K. A.; Maresso, A. W.

10.1101/2023.05.31.543151 — microbiology — Posted on 2023-06-01

4440 Correlation between antibacterial activity of two Artemisia sp. extracts and their plant characteristics

Mashraqi, A.; Al Abboud, M. A.; Ismail, K. S.; Modafer, Y.; Sharma, M.; El-Shabasy, A.

10.1101/2023.05.30.542989 — microbiology — Posted on 2023-06-01

4441 The zebrafish mutant dreammist implicates sodium homeostasis in sleep regulation

Barlow, I. L.; Mackay, E.; Wheater, E.; Goel, A.; Lim, S.; Zimmerman, S.; Woods, I.; Prober, D. A.; Rihel, J.

10.1101/2020.11.18.388736 — neuroscience — Posted on 2023-06-01

4442 Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity

Chitraju, C.; Fischer, A. W.; Ambaw, Y. A.; Wang, K.; Yuan, B.; Hui, S. T.; Walther, T. C.; Farese, R.

10.1101/2022.05.05.490833 — physiology — Posted on 2023-06-01

4443 Remodelling of the endothelial cell transcriptional program via paracrine and DNA-binding activities of MPO

Zheng, R.; Moynahan, K.; Georgomanolis, T.; Geissen, S.; Pavlenko, E.; Mizi, A.; Grimm, S.; Nemade, H.; Rehimi, R. R.; Bastigkeit, J.; Lackmann, J.-W.; Adam, M.; Rada-Iglesias, A.; Nuernberg, P.; Klinke, A.; Poepsel, S.; Baldus, S.; Papantonis, A.; Kargapolova, Y.

10.1101/2023.05.30.542845 — genomics — Posted on 2023-06-01

4444 Anaerobic gut fungal communities in marsupial hosts

Jones, A.; Pratt, C.; Meili, C.; Soo, R. M.; Hugenholtz, P.; Elshahed, M.; Youssef, N. H.

10.1101/2023.05.31.543067 — microbiology — Posted on 2023-06-01

4445 Wolbachia-induced inhibition of O'nyong nyong virus in Anopheles mosquitoes is mediated by Toll signaling and modulated by cholesterol

Pujhari, S.; Hughes, G. L.; Pakpour, N.; Suzuki, Y.; Rasgon, J. L.

10.1101/2023.05.31.543096 — microbiology — Posted on 2023-06-01

4446 Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release

Zhou, X.; Stine, C.; Prada, P. O.; Fusca, D.; Assoumou, K.; Dernic, J.; Bhat, M. A.; Achanta, A. S.; Johnson, J. C.; Jadhav, S.; Bauder, C. A.; Steuernagel, L.; Ravotto, L.; Benke, D.; Weber, B.; Stoeber, M.; Kloppenburg, P.; Bruening, J. C.; Bruchas, M. R.; Patriarchi, T.

10.1101/2023.05.26.542102 — neuroscience — Posted on 2023-06-01

4447 Omicron's Intrinsic Gene-Gene Interactions Jumped Away from Earlier SARS-CoV-2 Variants and Gene Homologs between Humans and Animals

Zhang, Z.

10.1101/2023.02.01.526736 — bioinformatics — Posted on 2023-06-01

4448 MuLan-Methyl - Multiple Transformer-based Language Models for Accurate DNA Methylation Prediction

Zeng, W.; Gautam, A.; Huson, D. H.

10.1101/2023.01.04.522704 — bioinformatics — Posted on 2023-06-01

4449 CLOOME: contrastive learning unlocks bioimaging databases for queries with chemical structures

Sanchez-Fernandez, A.; Rumetshofer, E.; Hochreiter, S.; Klambauer, G.

10.1101/2022.11.17.516915 — bioinformatics — Posted on 2023-06-01

4450 Low-usage splice junctions underpin immune-mediated disease risk

El Garwany, O.; Panousis, N. I.; Knights, A.; Kumasaka, N.; Imaz, M.; Vilarino, L. B.; Tsingene, A.; Barnett, A.; Gomez, C.; Gaffney, D. J.; Anderson, C. A.

10.1101/2023.05.29.542728 — genomics — Posted on 2023-06-01

4451 P-DOR, an easy-to-use pipeline to reconstruct outbreaks using pathogen genomics

Batisti Biffignandi, G.; Bellinzona, G.; Petazzoni, G.; Sassera, D.; Zuccotti, G. V.; Bandi, C.; Baldanti, F.; Comandatore, F.; Gaiarsa, S.

10.1101/2023.05.30.542810 — microbiology — Posted on 2023-06-01

4452 Cyanide-dependent control of terminal oxidase hybridization by Pseudomonas aeruginosa MpaR

Smiley, M. K.; Sekaran, D. C.; Price-Whelan, A.; Dietrich, L. E. P.

10.1101/2023.05.31.543164 — microbiology — Posted on 2023-06-01

4453 Developing appendable memory system towards permanent memory for artificial intelligence to acquire new knowledge after deployment

Yamada, K. D.

10.1101/2023.05.25.542376 — neuroscience — Posted on 2023-06-01

4454 A framework for identifying fertility gene targets for mammalian pest control

Clark, A. C.; Alexander, A.; Edison, R.; Esvelt, K.; Kamau, S.; Dutoit, L.; Champer, J.; Champer, S. E.; Messer, P. W.; Gemmell, N. J.

10.1101/2023.05.30.542751 — genetics — Posted on 2023-06-01

4455 Yeast Ixr1 mediates the DNA replication stress response through it HMGB DNA binding domains and interaction with checkpoint Mrc1

Zhang, X.; Teng, S.; Wang, Y.; Jiang, J.; Li, M.; Liu, Y.; Guan, Y.; Wei, A.; Cong, Z.

10.1101/2023.05.30.542938 — genetics — Posted on 2023-06-01

4456 Rhizoctonia solani disease suppression: addition of keratin-rich soil amendment leads to functional shifts in soil microbial communities

Russ, L.; Andreo Jimenez, B.; Nijhuis, E.; Postma, J.

10.1101/2023.05.31.543058 — microbiology — Posted on 2023-06-01

4457 The Toxoplasma gondii effector GRA83 modulates the host's innate immune response to regulate parasite infection

Thind, A. C.; Mota, C. M.; Goncalves, A. P. N.; Sha, J.; Wohlschlegel, J. A.; Mineo, T. W.; Bradley, P. J.

10.1101/2023.05.31.543158 — microbiology — Posted on 2023-06-01

4458 Bridging the gap between movement data and connectivity analysis using the time-explicit Step Selection Function (tSSF)

Valle, D.; Attias, N.; Cullen, J.; Hooten, M.; Giroux, A.; Santos, L.; Desbiez, A.; Fletcher, R.

10.1101/2023.05.29.542702 — animal behavior and cognition — Posted on 2023-06-01

4459 Emergence of Darwinian evolution in Bayesian collectives

Csillag, M.; Giaffar, H.; Szathmary, E.; Czegel, D.

10.1101/2023.05.29.542733 — evolutionary biology — Posted on 2023-06-01

4460 A comprehensive evolutionary scenario for the origin and neofunctionalization of the Drosophila speciation gene Odysseus (OdsH)

Vilas Boas Nunes, W.; Siqueira de Oliveira, D.; de Rezende Dias, G.; Carvalho, A. B.; Caruso, I. P.; Matos Biselli, J.; Gueguen, N.; Akkouche, A.; Burlet, N.; Vieira, C.; Carareto, C. M. A.

10.1101/2023.05.31.542109 — evolutionary biology — Posted on 2023-06-01

4461 Role of XerCD in release of over-replicated DNA through Outer Membrane Vesicles in Escherichia coli

Mansky, J.; Wang, H.; Wagner-Döbler, I.; Tomasch, J.

10.1101/2023.05.30.542921 — microbiology — Posted on 2023-06-01

4462 Selective targeting of α4β7/MAdCAM-1 axis suppresses liver fibrosis by reducing proinflammatory T cell recruitment to the liver

Gupta, B.; Rai, R. P.; Pal, P. B.; Chaudhary, S.; Chiaro, A.; Seaman, S.; Singhi, A. D.; Monga, S. P.; Iyer, S. S.; Raeman, R.

10.1101/2023.02.20.528201 — immunology — Posted on 2023-06-01

4463 A semi-quantitative, rapid, point of care SARS-CoV-2 serologic assay predicts neutralizing antibody levels

Markmann, A. J.; Bhowmik, D. R.; Jiang, B.; Van Hoy, M.; Wang, F.; Hou, Y. J.; Baric, R. S.; de Silva, A. M.; Bartelt, L. A.

10.1101/2023.05.30.542314 — immunology — Posted on 2023-06-01

4464 CD4+ T-cell immunity of SARS-CoV-2 patients determine pneumonia development

Naito, E.; Uchida, T.; Yamasaki, S.; Hashimoto, K.; Miura, Y.; Shiono, A.; Kawamura, T.; Mouri, A.; Yamaguchi, O.; Imai, H.; Kaira, K.; Nemoto, M.; Mitsutake, K.; Nagata, M.; Kagamu, H.

10.1101/2023.05.31.543129 — immunology — Posted on 2023-06-01

4465 Contributions of early and mid-level visual cortex to high-level object categorization

Kramer, L. E.; Konkle, T.; Chen, Y.-C.; Long, B.; Cohen, M. R.

10.1101/2023.05.31.541514 — neuroscience — Posted on 2023-06-01

4466 Tuning methylation-dependent silencing dynamics by synthetic modulation of CpG density

Ma, Y.; Budde, M. W.; Zhu, J.; Elowitz, M.

10.1101/2023.05.30.542205 — synthetic biology — Posted on 2023-06-01

4467 genomicBERT and data-free deep-learning model evaluation

Chen, T.; Tyagi, N.; Chauhan, S.; Peleg, A. Y.; Tyagi, S.

10.1101/2023.05.31.542682 — bioinformatics — Posted on 2023-06-01

4468 Boosting Single-Cell RNA Sequencing Analysis with Simple Neural Attention

Davalos, O. A.; Heydari, A. A.; Fertig, E. J.; Sindi, S.; Hoyer, K. K.

10.1101/2023.05.29.542760 — bioinformatics — Posted on 2023-06-01

4469 Profiling sorghum-microbe interactions with a specialized photoaffinity probe identifies key sorgoleone binders in Acinetobacter pittii

Kroll, J. O.; Van Fossen, E. M.; Anderson, L. N.; McNaughton, A. D.; Herrera, D.; Oda, Y.; Wilson, A. J.; Nelson, W. C.; Kumar, N.; Frank, A. R.; Elmore, J. R.; Handakumbura, P.; Lin, V. S.; Egbert, R. G.

10.1101/2023.05.31.542302 — biochemistry — Posted on 2023-06-01

4470 Distance sampling with vehicle-mounted cameras for the estimation of farmland bird abundance over a wide area.

Kumada, N.; Fukasawa, K.; Yoshioka, A.; Tsuda, N.; Ouchi, H.

10.1101/2023.05.31.540128 — ecology — Posted on 2023-06-01

4471 Single cell-guided prenatal derivation of primary epithelial organoids from the human amniotic and tracheal fluids.

Gerli, M. F. M.; Cala, G.; Beesley, M. A.; Sina, B.; Tullie, L.; Panariello, F.; Michielin, F.; Sun, K. Y.; Davidson, J. R.; Russo, F. M.; Jones, B. C.; Lee, D.; Savvidis, S.; Xenakis, T.; Simcock, I. C.; Straatman-Iwanowska, A. A.; Hirst, R. A.; David, A. L.; O'Callaghan, C.; Olivo, A.; Eaton, S.; Loukogeorgakis, S. P.; Cacchiarelli, D.; Deprest, J.; Li, V. S.; Giobbe, G. G.; De Coppi, P.

10.1101/2023.05.31.539801 — cell biology — Posted on 2023-06-01

4472 Distinct neural representations during a brain-machine interface and manual reaching task in motor cortex, prefrontal cortex, and striatum

Zippi, E. L.; Shvartsman, G. F.; Vendrell-Llopis, N.; Wallis, J. D.; Carmena, J. M.

10.1101/2023.05.31.542532 — neuroscience — Posted on 2023-06-01

4473 Preserved recognition of basic visual features despite lack of awareness of shape: evidence from a case of neglect

Akbiyik, S.; Schubert, T.; Caramazza, A.

10.1101/2023.05.30.541805 — neuroscience — Posted on 2023-06-01

4474 Single-cell Spatial Metabolic and Immune Phenotyping of Head and Neck Cancer Tissues Identifies Tissue Signatures of Response and Resistance to Immunotherapy

Jhaveri, N.; Ben Cheikh, B.; Nikulina, N.; Ma, N.; Klymyshyn, D.; DeRosa, J.; Mihani, R.; Pratapa, A.; Kassim, Y.; Bommakanti, S.; Shang, O.; He, Y.; Zheng, Y.; Monkman, J.; Cooper, C.; O'Byrne, K.; Anand, B.; Prater, M.; Basu, S.; Hughes, B. G. M.; Kulasinghe, A.; Braubach, O.

10.1101/2023.05.30.540859 — cancer biology — Posted on 2023-06-01

4475 Universal features of Nsp1-mediated translational shutdown by coronaviruses

Schubert, K.; Karousis, E. D.; Ban, I.; Lapointe, C.; Leibundgut, M.; Baeumlin, E.; Kummerant, E.; Scaiola, A.; Schoenhut, T.; Ziegelmueller, J.; Puglisi, J.; Muehlemann, O.; Ban, N.

10.1101/2023.05.31.543022 — biochemistry — Posted on 2023-06-01

4476 Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation

Asai, R.; Prakash, V. N.; Sinha, S.; Prakash, M.; Mikawa, T.

10.1101/2023.05.26.542486 — developmental biology — Posted on 2023-06-01

4477 ACTIVATION OF CYCLIN-DEPENDENT KINASE 5 BROADENS ACTION POTENTIALS IN HUMAN SENSORY NEURONS

Tiwari, M. N.; Hall, B. E.; Terse, A.; Amin, N.; Chung, M.-K.; Kulkarni, A.

10.1101/2023.05.31.543017 — neuroscience — Posted on 2023-06-01

4478 BrainAGE as a measure of maturation during early adolescence

Whitmore, L. B.; Weston, S. J.; Mills, K. L.

10.1101/2023.05.31.542949 — neuroscience — Posted on 2023-06-01

4479 The Effects of Dual-Site Beta tACS over the rIFG and preSMA on Response Inhibition in Young and Older Adults

Tan, J.; Iyer, K. K.; Nitsche, M. A.; Puri, R.; Hinder, M. R.; Fujiyama, H.

10.1101/2022.11.30.518460 — neuroscience — Posted on 2023-06-01

4480 IDSL.CSA: Composite Spectra Analysis for Chemical Annotation of Untargeted Metabolomics Datasets

Fakouri-baygi, S.; Kumar, Y.; Barupal, D. K.

10.1101/2023.02.09.527886 — bioinformatics — Posted on 2023-06-01

4481 A Rigid Parallel-Plate Artificial Placenta Oxygenator with a Hemocompatible Blood Flow Path

Blauvelt, D. G.; Higgins, N. C.; De, B.; Goodin, M. S.; Wright, N.; Blaha, C.; Moyer, J.; Chui, B. W.; Baltazar, F. J.; Oishi, P.; Roy, S.

10.1101/2022.08.23.505025 — bioengineering — Posted on 2023-06-01

4482 Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression

Lin, J.; Wen, Y.; Tang, J.; Zhang, X.; Zhang, H.; Zhu, H.

10.1101/2023.05.31.543169 — genomics — Posted on 2023-06-01

4483 The macroevolutionary dynamics of mammalian sexual size dimorphism

Jones, M. E.; Sheard, C.

10.1101/2023.05.31.543075 — evolutionary biology — Posted on 2023-06-01

4484 Weak seed banks influence the signature and detectability of selective sweeps

Korfmann, K.; Abu Awad, D.; Tellier, A.

10.1101/2022.04.26.489499 — evolutionary biology — Posted on 2023-06-01

4485 Phase-locking of neural activity to the envelope of speech in the delta frequency band reflects differences between word lists and sentences

Mohammadi, Y.; Graversen, C.; Ostergaard, J.; Kaeseler Andersen, O.; Reichenbach, T.

10.1101/2023.05.31.543025 — neuroscience — Posted on 2023-06-01

4486 Subcortical circuit dysfunctions delay perceptual decision-making in autism models

Burnett, L. E.; Koppensteiner, P.; Symonova, O.; Masson, T.; Vega-Zuniga, T.; Contreras, X.; Ruelicke, T.; Shigemoto, R.; Novarino, G.; Joesch, M.

10.1101/2022.10.11.511691 — neuroscience — Posted on 2023-06-01

4487 Generating human neural diversity with a multiplexed morphogen screen in organoids

Amin, N. D.; Kelley, K. W.; Hao, J.; Miura, Y.; Narazaki, G.; Li, T.; McQueen, P.; Kulkarni, S.; Pavlov, S.; Pasca, S. P.

10.1101/2023.05.31.541819 — neuroscience — Posted on 2023-06-01

4488 Not one size fits all: influence of EEG type when training a deep neural network for interictal epileptiform discharge detection

da Silva Lourenco, C.; Tjepkema-Cloostermans, M.; van Putten, M.

10.1101/2023.03.02.530752 — neuroscience — Posted on 2023-06-01

4489 Single cell spatial analysis and biomarker discovery in Hodgkin lymphoma

Xu, A. M.; Jiang, A.; Aoki, T.; Gamboa, A.; Chong, L.; Colombo, A. R.; Yin, Y.; Lownik, J.; Takata, K.; Hav, M.; Steidl, C.; Merchant, A.

10.1101/2023.05.24.542195 — cancer biology — Posted on 2023-06-01

4490 BRCA1 Hypermethylation In Sporadic Breast Cancers: Discovering A Novel Pathway To Tumorigenesis Via Coordinate NBR2 Deregulation And TNBC Transformation

Patra, D.; Varghese, G. R.; Jaikumar, V. S.; Rajan, A.; Krishnan, N.; Kuppuswamy, K.; Thankappan, R.; Srinivas, P.

10.1101/2022.04.30.490082 — cancer biology — Posted on 2023-06-01

4491 Assessing Fairness of AlphaFold2 Prediction of Protein 3D Structures

Abbas, U. L.; Chen, J.; Shao, Q.

10.1101/2023.05.23.542006 — bioinformatics — Posted on 2023-06-01

4492 Leveraging information between multiple population groups and traits improves fine-mapping resolution

Zhou, F.; Soremekun, O.; Chikowore, T.; Fatumo, S.; Barroso, I.; Morris, A.; Asimit, J. L.

10.1101/2023.05.31.543028 — genomics — Posted on 2023-06-01

4493 Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Tixi, W.; Maldonado, M.; Chang, Y.-T.; Parveen, N.; Chiu, A.; Yeung, W.; Nelson, M.; Hart, R. G.; Wang, S.; Hsu, W. J.; Fueger, P. T.; Kopp, J. L.; Huising, M. O.; Dhawan, S.; Shih, H.-P.

10.1101/2022.04.27.489466 — developmental biology — Posted on 2023-06-01

4494 A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression

Zhang, J.; Yan, C.; Xiong, J.; Zhou, Z.; Li, Q.; Gao, C.; Zhang, M.; Yu, L.; Li, J.; Hu, M.-M.; Zhang, C.-S.; Cai, C.; Zhang, H.

10.1101/2023.02.17.528944 — cell biology — Posted on 2023-06-01

4495 Audiotactile stimulation can improve syllable discrimination through multisensory integration in the theta frequency band

Guilleminot, P. H.; Graef, C.; Butters, E.; Reichenbach, T.

10.1101/2023.05.31.543034 — neuroscience — Posted on 2023-06-01

4496 Dual receptive fields underlying target and wide-field motion sensitivity in looming sensitive descending neurons

Nicholas, S.; Ogawa, Y.; Nordstrom, K.

10.1101/2022.10.19.512946 — neuroscience — Posted on 2023-06-01

Archive, 2023-06