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Archive, 2023-12

3 A Leak K+ Channel TWK-40 Regulates Rhythmic Motor Program in C. elegans
Yue, Z.; Li, Y.; Yu, B.; Xu, Y.; Chen, L.; Chitturi, J.; Meng, J.; Hung, W.; Tian, Y.; Mouridi, S. E.; Zhang, C.; Boulin, T.; Zhen, M.; Gao, S.
10.1101/2022.04.09.487752 — neuroscience — Posted on 2023-12-31
5 An Efficient and Safe Trans-complementation System of Mpox Virus Reproduces Authentic Viral Architecture and Infection
Liu, J.; Zhu, L.; Mei, L.; Liu, Y.; Qu, Y.; Yuan, Y.; Zhang, M.; Zhang, F.; Cao, Y.; Tai, W.; Ma, J.; Zheng, M.; Shi, X.; Liu, Y.; Cheng, G.
10.1101/2023.12.29.573498 — microbiology — Posted on 2023-12-31
9 Solid tumor growth depends on an intricate equilibrium of malignant cell states
Torborg, S. R.; Grbovic-Huezo, O.; Singhal, A.; Holm, M.; Wu, K.; Han, X.; Ho, Y.-J.; Haglund, C.; Mitchell, M. J.; Lowe, S. W.; Dow, L. E.; Pitter, K. L.; Sanchez-Rivera, F. J.; Levchenko, A.; Tammela, T.
10.1101/2023.12.30.573100 — cancer biology — Posted on 2023-12-30
10 The effects of cell-cell orientation in modeling the hallmarks of lung cancer in vitro
Espinoza, A. S.; McVicar, R. N.; Finlay, D.; Murad, R.; Vuori, K.; Grimmig, B. A.; Bush, A.; Smith, E.; Mandel-Clausen, T.; McGee, H. M.; Snyder, E. Y.; Leibel, S. L.
10.1101/2023.12.30.573475 — cancer biology — Posted on 2023-12-30
12 Developmentally dynamic changes in DNA methylation in the human pancreas
MacCalman, A.; De Franco, E.; Franklin, A.; Flaxman, C. S.; Richardson, S. J.; Murrall, K.; Barts Pancreas Tissue Bank, ; Burrage, J.; Walker, E.; Morgan, N. G.; Hattersley, A.; Dempster, E. L.; Hannon, E.; Jeffries, A. R.; Owens, N. D. L.; Mill, J.
10.1101/2023.10.19.563104 — genomics — Posted on 2023-12-31
13 PINK1 and BNIP3 mitophagy inducers have an antagonistic effect on Rbf1-induced apoptosis in Drosophila.
FAGES, M.; RUBY, V.; BRUSSON, M.; RINCHEVAL-ARNOLD, A.; WINTZ, C.; BOULEAU, S.; GUENAL, I.
10.1101/2023.12.10.568976 — cell biology — Posted on 2023-12-31
14 Targeting neuroinflammation by pharmacologic down-regulation of inflammatory pathways is neuroprotective in protein misfolding disorders.
Risen, S. J.; Boland, S.; Sharma, S.; Weismann, G.; Shirley, P.; Latham, A. S.; Hay, A. J. D.; Gilberto, V. S.; Hines, A. D.; Brindley, S.; Brown, J. M.; McGrath, S.; Chatterjee, A.; Nagpal, P.; Moreno, J. A.
10.1101/2022.09.26.509513 — neuroscience — Posted on 2023-12-31
17 Saponin Nanoparticle Adjuvants Incorporating Toll-Like Receptor Agonists Improve Vaccine Immunomodulation
Ou, B. S.; Baillet, J.; Filsinger Interrante, M. V.; Adamska, J. Z.; Zhou, X.; Saouaf, O.; Yan, J.; Klich, J.; Jons, C. K.; Meany, E.; Valdez, A. S.; Carter, L.; Pulendran, B.; King, N. P.; Appel, E.
10.1101/2023.07.16.549249 — bioengineering — Posted on 2023-12-31
19 Plasma Glycomic Markers of Accelerated Biological Aging During Chronic HIV Infection
Giron, L. B.; Liu, Q.; Adeniji, O. S.; Yin, X.; Kannan, T.; Ding, J.; Lu, D. Y.; Langan, S.; Zhang, J.; Azevedo, J. L. L. C.; Li, S. H.; Shalygin, S.; Azadi, P.; Hanna, D. B.; Ofotokun, I.; Lazar, J.; Fischl, M. A.; Haberlen, S.; Macatangay, B.; Adimora, A. A.; Jamieson, B. D.; Rinaldo, C.; Merenstein, D.; Roan, N. R.; Kutsch, O.; Gange, S.; Wolinsky, S.; Witt, M.; Post, W. S.; Kossenkov, A.; Landay, A.; Frank, I.; Tien, P. C.; Gross, R.; Brown, T. T.; Mohsen, M. A.
10.1101/2023.08.09.551369 — microbiology — Posted on 2023-12-31
20 Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
Henderson, R.; Anasti, K.; Manne, K.; Stalls, V.; Saunders, C.; Bililign, Y.; Williams, A.; Bubphamala, P.; Montani, M.; Kachhap, S.; Li, J.; Jaing, C.; Newman, A.; Cain, D.; Lu, X.; Venkatayogi, S.; Berry, M.; Wagh, K.; Korber, B.; Saunders, K. O.; Tian, M.; Alt, F.; Wiehe, K.; Acharya, P.; Alam, S. M.; Haynes, B. F.
10.1101/2023.12.15.571700 — immunology — Posted on 2023-12-31
22 A putative rhamnogalacturonan-II CMP-β-Kdo transferase identified using CRISPR/Cas9 gene edited callus to circumvent embryo lethality.
Zhang, Y.; Sharma, D.; Liang, Y.; Downs, N.; Dolman, F.; Thorne, K.; Black, I.; Pereira, J. H.; Adams, P. D.; Scheller, H.; O'Neill, M.; Urbanowicz, B. R.; Mortimer, J. C.
10.1101/2023.11.15.567147 — plant biology — Posted on 2023-12-31
23 Synergistic induction of blood-brain barrier properties
Porkolab, G.; Meszaros, M.; Szecsko, A.; Vigh, J. P.; Walter, F. R.; Figueiredo, R.; Kalomista, I.; Hoyk, Z.; Vizsnyiczai, G.; Grof, I.; Jan, J.-S.; Gosselet, F.; Pirity, M. K.; Vastag, M.; Hudson, N.; Campbell, M.; Veszelka, S.; Deli, M. A.
10.1101/2023.02.09.527899 — bioengineering — Posted on 2023-12-30
24 The two key substitutions in the chromophore environment of mKate2 to produce an enhanced FusionRed-like red fluorescent protein
Ruchkin, D. A.; Gavrikov, A. S.; Kolesov, D. V.; Gorokhovatsky, A. Y.; Chepurnykh, T. V.; Mishin, A. S.; Maximov, E. G.; Pletneva, N. V.; Pletnev, V. Z.; Lukyanov, K. A.; Bogdanov, A. M.
10.1101/2023.12.05.570295 — molecular biology — Posted on 2023-12-31
29 MetalinksDB: a flexible and contextualizable resource of metabolite-protein interactions
Farr, E. B.; Dimitrov, D.; Turei, D.; Schmidt, C.; Lobentanzer, S.; Dugourd, A.; Saez-Rodriguez, J.
10.1101/2023.12.30.573715 — systems biology — Posted on 2023-12-30
30 Peptide fibrils as vaccine: a proof of concept
Zabrodskaya, Y.; Sivak, K.; Sergeeva, M.; Aleksandrov, A.; Kalinina, E.; Taraskin, A.; Eropkin, M.; Eropkina, E.; Egorov, V.
10.1101/2023.12.30.573725 — biophysics — Posted on 2023-12-30
34 Threshold of somatic mosaicism disrupting the brain function
Kim, J.; Park, S. M.; Koh, H. Y.; Ko, A.; Kang, H.-C.; Chang, W. S.; Kim, D. S.; Lee, J. H.
10.1101/2023.12.30.573716 — genetics — Posted on 2023-12-30
38 The packaging signal of Xanthomonas integrative filamentous phages
Yeh, T.-Y.; Feehley, P. J.; Feehley, M. C.; Ooi, V. Y.; Wu, P.-C.; Hsieh, F.; Chiu, S. S.; Su, Y.-C.; Lewis, M. S.; Contreras, G. P.
10.1101/2023.12.30.573655 — molecular biology — Posted on 2023-12-30
39 Exposure and resistance to lantibiotics impact microbiota composition and function
Zhang, Z. J.; Cole, C.; Lin, H.; Wu, C.; Haro, F.; McSpadden, E.; van der Donk, W.; Pamer, E. G.
10.1101/2023.12.30.573728 — microbiology — Posted on 2023-12-30
40 Trivalent mRNA vaccine-candidate against seasonal flu with cross-specific humoral immune response
Mazunina, E. P.; Gushchin, V. A.; Kleymenov, D. A.; Sinyavin, A. E.; Burtseva, E. I.; Shmarov, M. M.; Mukasheva, E. A.; Bykonia, E. N.; Kozlova, S. R.; Evgrafova, E. A.; Zolotar, A. N.; Shidlovskaya, E. V.; Kirillova, E. S.; Krepkaia, A. S.; Usachev, E. V.; Kuznetsova, N. A.; Ivanov, I. A.; Dmitriev, S. E.; Ivanov, R. A.; LOGUNOV, D.; Gintsburg, A. L.
10.1101/2023.12.30.573722 — immunology — Posted on 2023-12-30
41 Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia
Ardaya, M.; Tiveron, M.-C.; Cremer, H.; Dehay, B.; Perez-Cerda, F.; Matute, C.; Soria, F. N.; Cavaliere, F.
10.1101/2023.12.30.573719 — neuroscience — Posted on 2023-12-30
43 Integrating multiple omics levels using the human protein complexome as a framework, a multi-omics study of inborn errors of metabolism
Guharoy, M.; Adant, I.; Bird, M.; Pedrayes, A. J.; Botzki, A.; Dehairs, J.; Derveaux, S.; Devos, S.; Goeminne, G.; Impens, F.; Janky, R.; Maes, R.; Maia, T. M.; Meersseman, W.; Rymen, D.; Swinnen, J. V.; Van Haver, D.; Witters, P.; Cassiman, D.; Ghesquiere, B.
10.1101/2023.12.30.573613 — biochemistry — Posted on 2023-12-30
44 Plant breeding simulations with AlphaSimR
Bancic, J.; Greenspoon, P.; Gaynor, C. R.; Gorjanc, G.
10.1101/2023.12.30.573724 — genetics — Posted on 2023-12-30
45 Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment
Zhu, M.; Frank, M. W.; Radka, C. D.; Jeanfavre, S.; Tse, M. W.; Avila Pacheco, J.; Pierce, K.; Deik, A.; Xhu, J.; Hussain, S.; Hussain, F. A.; Xulu, N.; Khan, N.; Pillay, V.; Dong, K. L.; Ndung'u, T.; Clish, C. B.; Rock, C. O.; Blainey, P. C.; Bloom, S. M.; Kwon, D. S.
10.1101/2023.12.30.573720 — microbiology — Posted on 2023-12-30
47 A highly contiguous hexaploid wheat genome assembly facilitates analysis of 1RS translocation and mining of a new adult plant resistance locus to yellow rust disease
Li, G.; Ren, Y.; Yang, Y.; Chen, S.; Zheng, J.; Zhang, X.; Chen, M.; Sun, X.; Lv, C.; Li, X.; Li, Y.; Dong, C.; Tang, J.; Huang, Z.; Peng, Y.; Gu, D.; Wang, Z.; Zheng, H.; Shi, C.; Kang, G.; Zheng, T.; Chen, F.; Wang, D.; Zhang, K.; Yin, G.
10.1101/2023.12.30.573687 — genomics — Posted on 2023-12-30
49 Partial RNA Design
Runge, F.; Franke, J. K. H.; Fertmann, D.; Backofen, R.; Hutter, F.
10.1101/2023.12.29.573656 — bioinformatics — Posted on 2023-12-30
56 Genomic Underground: Unraveling NUMTs in Mole Voles
Prokopov, D.; Saluev, T.; Romanenko, S.; Bakloushinskaya, I.; Graphodatsky, A.
10.1101/2023.12.30.573699 — genomics — Posted on 2023-12-30
57 A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on ER-stress independent β cell apoptosis in a patient with Wolfram syndrome.
Chimienti, R.; Torchio, S.; Zamarian, V.; Siracusano, G.; Monaco, L.; Lombardo, M. T.; Manenti, F.; Cuozzo, F.; Rossi, G.; Carrera, P.; Sordi, V.; Broccoli, V.; Bonfanti, R.; Casari, G.; Frontino, G.; Piemonti, L.
10.1101/2023.12.29.573188 — genetics — Posted on 2023-12-30
58 Soils-on-a-chip reveal unforeseen motility parameters of confined Bradyrhizobium diazoefficiens
Pires Monteiro, M.; Carrillo, J. P.; Gutierrez, N.; Montagna, S.; Lodeiro, A. R.; Cordero, M. L.; Marconi, V. I.
10.1101/2023.12.29.573673 — ecology — Posted on 2023-12-30
61 Hexafluoro slows retinal degeneration and improves visual function in zebrafish models of Usher syndrome 1F
Phillips, J. B.; Kulis, S.; Buchner, S. H.; Fox, E. J.; Wegner, J.; Pierce, J.; Ivanchenko, M. V.; Corey, D. P.; Arbiser, J. L.; Westerfield, M.
10.1101/2023.12.29.573664 — neuroscience — Posted on 2023-12-30
62 Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA Polymerase II productive elongation.
Cornejo, K. G.; Venegas, A.; Sono, M. H.; Door, M.; Gutierrez-Ruiz, B.; Karabedian, L. B.; Nandi, S. G.; Dykhuizen, E. C.; Saha, R. N.
10.1101/2023.12.30.573688 — neuroscience — Posted on 2023-12-30
63 Protosequences in human cortical organoids model intrinsic states in the developing cortex
Tjitse van der Molen, T.; Spaeth, A.; Chini, M.; Bartram, J.; Dendukuri, A.; Zhang, Z.; Bhaskaran-Nair, K.; Blauvelt, L. J.; Petzold, L. R.; Hansma, P. K.; Teodorescu, M.; Hierlemann, A.; Hengen, K. B.; Hanganu-Opatz, I. L.; Kosik, K. S.; Sharf, T.
10.1101/2023.12.29.573646 — neuroscience — Posted on 2023-12-30
64 Pannexin 1 Channels Control Cardiomyocyte Metabolism and Neutrophil Recruitment During Non-Ischemic Heart Failure
Pavelec, C. M.; Young, A.; Luviano, H. L.; Orrell, E. E.; Poudel, N.; Wolpe, A. G.; Thomas, S. H.; Yeudall, S.; Upchurch, C.; Okusa, M. D.; Isakson, B. E.; Wolf, M. J.; Leitinger, N.
10.1101/2023.12.29.573679 — physiology — Posted on 2023-12-30
69 Pronounced early differentiation underlies zebra finch gonadal germ cell development.
Biegler, M. T.; Belay, K.; Wang, W.; Szi, C.; Collier, P. G.; Luo, J.-D.; Haase, B.; Gedman, G. L.; Sidhu, A. V.; Harter, E.; Rivera-Lopez, C.; Amoako-Boadu, K.; Fedrigo, O.; Tilgner, H. U.; Carroll, T. T.; Jarvis, E. D.; Keyte, A. L.
10.1101/2023.12.30.572255 — cell biology — Posted on 2023-12-30
71 Whole-brain modelling supports the use of serotonergic psychedelics for the treatment of disorders of consciousness
Mindlin, I.; Herzog, R.; Belloli, L.; Manasova, D.; Monge-Asensio, M.; Vohryzek, J.; Escrichs, A.; Alnagger, N.; Nunez, P.; Kringelbach, M. L.; Deco, G.; Tagliazucchi, E.; Naccache, L.; Rohaut, B.; Sitt, J. D.; Sanz Perl, Y.
10.1101/2023.12.29.573603 — neuroscience — Posted on 2023-12-30
75 Task goals shape the relationship between decision and movement speed
Fievez, F.; Cos, I.; Carsten, T.; Derosiere, G.; Zenon, A.; Duque, J.
10.1101/2023.12.29.573524 — neuroscience — Posted on 2023-12-30
76 Diversity and connectivity of principal neurons in the lateral and basal nuclei of the mouse amygdala
Reeb, Z.; Magyar, D.; Weisz, F.; Fekete, Z.; Muller, K.; Vikor, A.; Peterfi, Z.; Andrasi, T.; Veres, J.; Hajos, N.
10.1101/2023.12.29.573684 — neuroscience — Posted on 2023-12-30
77 Principles of visual cortex excitatory microcircuit organization
Chou, C. Y. C.; Wong, H. H.-W.; Guo, C.; Boukoulou, K. E.; Huang, C.; Jannat, J.; Klimenko, T.; Li, V. Y.; Liang, T. A.; Wu, V. C.; Sjöström, P. J.
10.1101/2023.12.30.573666 — neuroscience — Posted on 2023-12-30
78 Augmented gut hormone response to feeding in older adults exhibiting low appetite.
Dagbasi, A.; Warner, J.; Catterall, V.; Crabtree, D. R.; Carroll, B.; Frost, G.; Holliday, A.
10.1101/2023.12.29.573652 — physiology — Posted on 2023-12-30
81 Differential substrate specificity of ERK, JNK, and p38 MAP kinases toward Connexin 43
Latchford, L. P.; Perez, L. S.; Conage-Pough, J. E.; Turk, R.; Cusimano, M. A.; Vargas, V. I.; Arora, S.; White, F. M.; Thevenin, A. F.
10.1101/2023.12.30.573692 — biochemistry — Posted on 2023-12-30
82 Age-associated aberrations of cumulus-oocyte interaction and microfilamentous structure in the zona pellucida decline female fertility
Ishikawa-Yamauchi, Y.; Emori, C.; Mori, H.; Endo, T.; Kobayashi, K.; Watanabe, Y.; Sagara, H.; Nagata, T.; Motooka, D.; Ninomiya, A.; Ozawa, M.; Ikawa, M.
10.1101/2023.12.30.573680 — developmental biology — Posted on 2023-12-30
85 Nucleocytoplasmic transport rates are regulated by cellular processes that modulate GTP availability
Scott, K. L.; Halfmann, C. T.; Hoefakker, A. D.; Purkayastha, P.; Wang, T. C.; Lele, T. P.; Roux, K.
10.1101/2023.12.29.573651 — cell biology — Posted on 2023-12-30
89 Investigating genomic prediction strategies for grain carotenoid traits in a tropical/subtropical maize panel
LaPorte, M.-F.; Suwarno, W.; Hannok, P.; Koide, A.; Bradbury, P. J.; Crossa, J.; Palacios-Rojas, N.; Diepenbrock, C. H.
10.1101/2023.12.29.573624 — plant biology — Posted on 2023-12-30
90 The complete human diploid reference genome of RPE-1 identifies the phased epigenetic landscapes from multi-omics data
Volpe, E.; Corda, L.; Di Tommaso, E.; Pelliccia, F.; Ottalevi, R.; Licastro, D.; Guarracino, A.; Capulli, M.; Formenti, G.; Tassone, E.; Giunta, S.
10.1101/2023.11.01.565049 — genomics — Posted on 2023-12-30
93 KMT2A oncoproteins induce epigenetic resistance to targeted therapies
Janssens, D. H.; Duran, M.; Otto, D. J.; Kirkey, D.; Yi, J. S.; Meshinchi, S.; Sarthy, J. F.; Ahmad, K.; Henikoff, S.
10.1101/2023.12.29.573681 — cancer biology — Posted on 2023-12-30
99 Obesity modifies cell fate plasticity of Pdgfrα-expressing adipocyte progenitors to promote an aberrant mammary microenvironment
Kwende, S. A.; Nuthalapati, P.; Sunder Singh, J. P.; Maity, S.; Ning, D.; Shryock, D. G.; Xuan, Z.; Joshi, P. A.
10.1101/2023.12.28.573587 — cell biology — Posted on 2023-12-30
107 Genetic activation of canonical RNA interference in mice
Buccheri, V.; Pasulka, J.; Malik, R.; Loubalova, Z.; Taborska, E.; Horvat, F.; Kulmann, M. I. R.; Jenickova, I.; Prochazka, J.; Sedlacek, R.; Svoboda, P.
10.1101/2023.12.29.573630 — molecular biology — Posted on 2023-12-29
109 Image-Based Assessment of Natural Killer Cell Activity against Glioblastoma Stem Cells
Du, Y.; Metcalfe, S.; Akunapuram, S.; Richardson, A. M.; Cohen-Gadol, A. A.; Shen, J.
10.1101/2023.12.29.573629 — cancer biology — Posted on 2023-12-29
110 Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia
Spinler, K.; Hamilton, M.; Bajaj, J.; Shima, Y.; Diaz, E.; Kritzik, M.; Reya, T.
10.1101/2023.12.29.573601 — cancer biology — Posted on 2023-12-29
112 Identification of the potassium binding site in serotonin transporter SERT
Hellsberg, E.; Boytsov, D.; Chen, Q.; Niello, M.; Freissmuth, M.; Rudnick, G.; Zhang, Y.-W.; Sandtner, W.; Forrest, L. R.
10.1101/2023.12.29.573628 — biochemistry — Posted on 2023-12-29
116 Anti-dengue viral activity of Glycyrrhiza glabra roots in Vero cells
Jayasekera, K. G.; Suresh, S.; Goonasekera, C.; Soyza, P.; Perera, N.; Jayawardene, A.; gunasekera, k.
10.1101/2023.12.29.573598 — microbiology — Posted on 2023-12-29
117 Cyclo(Pro-Tyr) elicits conserved cellular damage in fungi by targeting the ATPase Pma1 in plasma membrane domains
Vela-Corcia, D.; Hierrezuelo, J.; Perez-Lorente, A. I.; Stincone, P.; Pakkir Shah, A. K.; Grelard, A.; de Vicente, A.; Perez-Garcia, A.; Loquet, A.; Petras, D.; Romero, D.
10.1101/2023.12.29.573620 — microbiology — Posted on 2023-12-29
118 Porphyromonas gingivalis fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion
Diaz Basabe, A.; Lattanzi, G.; Perillo, F.; Amoroso, C.; Baeri, A.; Farini, A.; Torrente, Y.; Penna, G.; Rescigno, M.; Ghidini, M.; Cassinotti, E.; Baldari, L.; Boni, L.; Vecchi, M.; Caprioli, F.; Facciotti, F.; Strati, F.
10.1101/2023.12.29.573607 — immunology — Posted on 2023-12-29
119 C5aR Expression in Kidney Tubules, Macrophages and Fibrosis
Dunlap, C.; Zhao, N.; Ertl, L. S.; Schall, T. J.; Sullivan, K.
10.1101/2023.12.29.573612 — immunology — Posted on 2023-12-29
120 Small-molecule degraders reduce Aβ production through CAPRIN1-mediated lysosomal degradation of APP in Alzheimer iPSC-derived neurons
Jung, S.; Jaiswal, N.; Rai, R. K.; Takagi, Y.; Lo, H.-Y.; Gao, C.; Zeng, L.; Wang, X.; Wohlford, R. K.; Higgins, R.; Bellail, A. C.; Hao, C.
10.1101/2023.12.29.573648 — neuroscience — Posted on 2023-12-29
122 Timp2 loss-of-function mutation and TIMP2 treatment in murine model of NSCLC: modulation of immunosuppression and oncogenic signaling
Peeney, D.; Kumar, S.; Singh, T. P.; Liu, Y.; Jensen, S.; Chowdhury, A.; Coates-Park, S.; Rich, J.; Gurung, S.; Fan, Y.; Meerzaman, D.; Stetler-Stevenson, W. G.
10.1101/2023.12.29.573636 — cancer biology — Posted on 2023-12-29
126 An Efficient and Safe Trans-complementation System of Mpox Virus Reproduces Authentic Viral Architecture and Infection
Liu, J.; Zhu, L.; Mei, L.; Liu, Y.; Qu, Y.; Yuan, Y.; Zhang, M.; Zhang, F.; Tai, W.; Ma, J.; Zheng, M.; Shi, X.; Liu, Y.; Cheng, G.
10.1101/2023.12.29.573498 — microbiology — Posted on 2023-12-29
127 Time-resolved transcriptomics reveal a mechanism of host niche defense: beneficial root endophytes deploy a host-protective antimicrobial GH18-CBM5 chitinase
Eichfeld, R.; Mahdi, L. K.; De Quattro, C.; Armbruster, L.; Endeshaw, A. B.; Miyauchi, S.; Hellmann, M. J.; Cord-Landwehr, S.; Grigoriev, I.; Peterson, D.; Singan, V.; Lail, K.; Savage, E.; Ng, V.; Langen, G.; Moerschbacher, B.; Zuccaro, A.
10.1101/2023.12.29.572992 — microbiology — Posted on 2023-12-29
128 Mechanisms underpinning osteosarcoma genome complexity and evolution
Espejo Valle-Inclan, J.; De Noon, S.; Trevers, K.; Elrick, H.; Tanguy, M.; Butters, T.; Muyas, F.; Amary, F.; Tirabosco, R.; Giess, A.; Sosinky, A.; Elgar, G.; Flanagan, A. M.; Cortes-Ciriano, I.
10.1101/2023.12.29.573403 — cancer biology — Posted on 2023-12-29
129 A spectrum of altered non-rapid eye movement sleep in schizophrenia
Kozhemiako, N.; Jiang, C.; Sun, Y.; Guo, Z.; Chapman, S.; Gai, G.; Wang, Z.; Zhou, L.; Li, S.; Law, R. G.; Wang, L. A.; Mylonas, D.; Shen, L.; Murphy, M.; Qin, S.; Zhu, W.; Zhou, Z.; Stickgold, R.; Huang, H.; Tan, S.; Manoach, D. S.; Wang, J.; Hall, M.-H.; Pan, J. Q.; Purcell, S. M.
10.1101/2023.12.28.573548 — neuroscience — Posted on 2023-12-29
130 Prognostic relevance of correlated co-expression of coding and noncoding RNAs in cervical cancers
Ghosh, A.; Sinha, A.; Ghosh, A.; Roy, S.; Mallick, S.; Kumar, V.; Mathai, S.; Bhaumik, J.; Mukhopadhyay, A.; Sen, S.; Chandra, A.; Maitra, A.; Biswas, N. K.; Majumder, P. P.; Sengupta, S.
10.1101/2023.12.28.573593 — cancer biology — Posted on 2023-12-29
131 Ketamine modulates a norepinephrine-astroglial circuit to persistently suppress futility-induced passivity
Duque, M.; Chen, A. B.; Hsu, E.; Narayan, S.; Rymbek, A.; Begum, S.; Saher, G.; Cohen, A. E.; Olson, D. E.; Prober, D. A.; Bergles, D. E.; Fishman, M. C.; Engert, F.; Ahrens, M. B.
10.1101/2022.12.29.522099 — neuroscience — Posted on 2023-12-29
132 Analysis of NIH K99/R00 Awards and the Career Progression of Awardees
Woitowich, N. C.; Hengel, S. R.; Solis, C.; Vilgalys, T. P.; Babdor, J.; Tyrrell, D. J.
10.1101/2023.01.26.525751 — scientific communication and education — Posted on 2023-12-29
133 Bidirectional Modulation Of Synaptic Transmission By Insulin-Like Growth Factor I
Noriega-Prieto, J. A.; Maglio, L. E.; Davila, J. C.; Gutierrez, A.; Torres Aleman, I.; Fernandez de Sevilla, D.
10.1101/2023.12.29.573627 — neuroscience — Posted on 2023-12-29
143 Improving the power of drug toxicity measurements by quantitative nuclei imaging
Mikheeva, A. M.; Bogomolov, M. A.; Sementsov, M. V.; Spirin, P. V.; Prassolov, V. S.; Lebedev, T.
10.1101/2023.12.28.573573 — cancer biology — Posted on 2023-12-29
144 Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
Cook, A. L.; Sur, S.; Dobbyn, L.; Watson, E.; Cohen, J. D.; Ptak, B.; Lee, B. S.; Paul, S.; Hsiue, E.; Popoli, M.; Vogelstein, B.; Papadopoulos, N.; Bettegowda, C.; Gabrielson, K.; Zhou, S.; Kinzler, K. W.; Wyhs, N.
10.1101/2023.12.28.573594 — cancer biology — Posted on 2023-12-29
145 Murine GMP- and MDP-derived classical monocytes have distinct functions and fates
Trzebanski, S.; Kim, J.-S.; Larrossi, N.; Kancheva, D.; Bastos, J.; Haddad, M.; Aizik, D.; Kralova, J.; Gross-Vered, M.; Boura-Halfon, S.; Lapidot, T.; Alon, R.; Movahedi, K.; Jung, S.; Sivan, E.; Solomon, A.; Raanan, A.
10.1101/2023.07.29.551083 — immunology — Posted on 2023-12-29
147 Molecular identification of wide-field amacrine cells in mouse retina that encode stimulus orientation
Park, S. J.; Lei, W.; Pisano, J.; Orpia, A.; Minehart, J.; Pottackal, J.; Hanke-Gogokhia, C.; Zapadka, T.; Clarkson-Paredes, C.; Popratiloff, A.; Ross, S. E.; Singer, J. H.; Demb, J.
10.1101/2023.12.28.573580 — neuroscience — Posted on 2023-12-29
156 Genome mining of Streptomyces for the discovery of low-resistance antibiotics
Rosete Ambriz, S. A.; Alejo Hernandez, M. A.; Sanchez Cruz, N.; Ceapa, C. D.
10.1101/2023.12.28.573565 — genomics — Posted on 2023-12-29
157 Obesity modifies cell fate plasticity of Pdgfrα-expressing mammary adipocyte progenitors to promote an aberrant mammary microenvironment
Kwende, S. A.; Nuthalapati, P.; Sunder Singh, J. P.; Maity, S.; Ning, D.; Shryock, D. G.; Xuan, Z.; Joshi, P. A.
10.1101/2023.12.28.573587 — cell biology — Posted on 2023-12-29
160 Deregulation cascades in carcinogenesis
Perez, R. H.; Gomez, J. P.; Perez, G. J. G.; Gonzalez, A.
10.1101/2023.12.28.573550 — systems biology — Posted on 2023-12-29
161 Morphological and yield responses of Cannabis sp. to night-time disruption.
Gonzalez Vanegas, B. S.; Sarmiento, F. S.; Calderon Martinez, C. J.; Osorio Lasso, V.
10.1101/2023.12.28.573579 — plant biology — Posted on 2023-12-29
163 Cell-Free Optimized Production of Protoporphyrin IX
Garcia, D. C.; Davies, J. P.; Rhea, K.; Lee, M. S.; Lux, M. W.
10.1101/2023.12.28.573540 — bioengineering — Posted on 2023-12-29
164 Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Mfn2 and Opa1
Boopathy, S.; Lugo, C. M.; Luce, B. E.; McDonald, J. L.; Hakim, P.; Ponce, J.; Ueberheide, B.; Chao, L. H.
10.1101/2023.12.29.573615 — biochemistry — Posted on 2023-12-29
166 Ultrastructural, metabolic and genetic determinants of the acquisition of macrolide resistance by Streptococcus pneumoniae
Wu, X.; Alibayov, B.; Xiang, X.; Lattar, S.; Sakai, F.; Medders, A. A.; Antezana, B.; Keller, L.; Vidal, A. G.; Tzeng, Y.-L.; Robinson, D. A.; Stephens, D.; Yua, Y.; Vidal, J. E.
10.1101/2023.12.27.573471 — microbiology — Posted on 2023-12-29
167 A neural network for religious fundamentalism derived from patients with brain lesions
Ferguson, M. A.; Asp, E. W.; Kletenik, I.; Tranel, D.; Boes, A.; Nelson, J. M.; Schaper, F. L.; Siddiqi, S. H.; Anderson, J. S.; Nielsen, J. A.; Bateman, J. R.; Grafman, J.; Fox, M. D.
10.1101/2023.12.22.572527 — neuroscience — Posted on 2023-12-29
169 A Leak K+ Channel TWK-40 Regulates Rhythmic Motor Program in C. elegans
Yue, Z.; Yu, B.; Li, Y.; Xu, Y.; Chen, L.; Chitturi, J.; Meng, J.; Hung, W.; Tian, Y.; Mouridi, S. E.; Zhang, C.; Boulin, T.; Zhen, M.; Gao, S.
10.1101/2022.04.09.487752 — neuroscience — Posted on 2023-12-29
171 The role of satellite cell-derived TRIM28 in mechanical load- and injury-induced myogenesis
Lin, K.-H.; Hibbert, J. E.; Lemens, J. L.; Torbey, M. M.; Steinert, N. D.; Flejsierowicz, P. M.; Melka, K. M.; Lares, M.; Setaluri, V.; Hornberger, T. A.
10.1101/2023.12.20.572566 — cell biology — Posted on 2023-12-29
173 Hypoxia Sensing in Resident Cardiac Macrophages Regulates Monocyte Fate Specification following Ischemic Heart Injury
Kadyrov, F. F.; Koenig, A. L.; Amrute, J. M.; Dun, H.; Li, W.; Weinheimer, C. J.; Nigro, J. M.; Kovacs, A.; Bredemeyer, A. L.; Lai, L.; Kopecky, B. J.; Penna, V.; Kreisel, D.; Lavine, K. J.
10.1101/2022.08.04.502542 — immunology — Posted on 2023-12-29
174 Restoring AIBP expression in the retina provides neuroprotection in glaucoma
Ju, W.-K.; Ha, Y.; Choi, S.; Kim, K.-Y.; Bastola, T.; Kim, J.; Weinreb, R. N.; Zhang, W.; Miller, Y. I.; Choi, S.-H.
10.1101/2023.10.16.562633 — neuroscience — Posted on 2023-12-29
175 Nutritional characterisation and seasonal variation of goat forages in Central Malawi
Cooke, A. S.; Mvula, W.; Ventura-Cordero, J.; Gwiriri, L. C.; Takahashi, T.; Morgan, E. R.; Lee, M. R. F.; Safalaoh, A.
10.1101/2023.12.22.573017 — zoology — Posted on 2023-12-29
177 Organ specific microenvironmental MR1 expression in cutaneous melanoma
Gordon, P. B.; So, W. Y.; Azubuike, U. F.; Johnson, B.; Cicala, J.; Sturgess, V.; Wong, C.; Bishop, K.; Bresciani, E.; Sood, R.; Ganesan, S.; Tanner, K.
10.1101/2023.12.28.573554 — cancer biology — Posted on 2023-12-28
178 Thermo-Responsive Polymers Targeting Inflammation in Murine Colitis
Zhang, S.; Jin, A. T.; Tang, W.; Zhang, R. Y.; Jing, L.; Zhou, Y.; Zhang, H.; Lennerz, J. K.; Korzenik, J. R.; Langer, R.; Traverso, G.
10.1101/2023.12.28.573545 — bioengineering — Posted on 2023-12-28
179 A single-cell transposable element atlas of human cell identity
Reyes-Gopar, H.; Marston, J. L.; Singh, B.; Greenig, M.; Lin, J.; Ostrowski, M. A.; Randall, K. N.; Sandoval-Motta, S.; Dopkins, N.; Lawrence, E.; O'Mara, M. M.; Fei, T.; Duarte, R. R. R.; Powell, T. R.; Hernandez-Lemus, E.; Iniguez, L. P.; Nixon, D. F.; Bendall, M. L.
10.1101/2023.12.28.573568 — genomics — Posted on 2023-12-28
180 Replication-driven HBV cccDNA loss in chimeric mice with humanized livers
Zhang, B.-H.; Zhou, Y.; Tempel, B.; Pan, H.; Horrigan, S.; Luckenbaugh, L.; Zoulim, F.; Hu, J.; Zhang, Y.-Y.
10.1101/2023.12.28.573542 — microbiology — Posted on 2023-12-28
183 Modeling the simultaneous dynamics of proteins in blood plasma and the cerebrospinal fluid in human in vivo
Giroux, P.; Vialaret, J.; Kindermans, J.; Gabelle, A.; Bauchet, L.; Hirtz, C.; Lehmann, S.; Colinge, J.
10.1101/2023.12.28.573559 — systems biology — Posted on 2023-12-28
186 Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships
Asquith, C. R. M.; East, M. P.; Laitinen, T.; Alamillo-Ferrer, C.; Hartikainen, E.; Wells, C. I.; Axtman, A. D.; Drewry, D. H.; Tizzard, G. J.; Poso, A.; Willson, T. M.; Johnson, G. L.
10.1101/2023.12.28.573261 — pharmacology and toxicology — Posted on 2023-12-28
187 Cross-Species Variability in Lobular Geometry and Cytochrome P450 Hepatic Zonation: Insights into CYP1A2, CYP2E1, CYP2D6 and CYP3A4
Albadry, M.; Kuettner, J.; Grzegorzewski, J.; Dirsch, O.; Kindler, E.; Klopfleisch, R.; Liska, V.; Moulisova, V.; Nickel, S.; Palek, R.; Rosendorf, J.; Saalfeld, S.; Settmacher, U.; Tautenhahn, H.-M.; König, M.; Dahmen, U.
10.1101/2023.12.28.573567 — pathology — Posted on 2023-12-28
189 Postnatal FGFR-signalling establishes gradients of cell identities along the proximal-distal axis of the lung airways
Sountoulidis, A.; Firsova, A. B.; Liontos, A.; Theelke, J.; Koepke, J.; Millar-Buchner, P.; Manneras-Holm, L.; Bjorklund, A. K.; Fysikopoulos, A.; Gaengel, K.; Backhed, F.; Betsholtz, C.; Seeger, W.; Bellusci, S.; Samakovlis, C.
10.1101/2023.12.11.571142 — cell biology — Posted on 2023-12-28
193 A systematic review of delayed cerebral ischemia in experimental mouse models after subarachnoid hemorrhage
Karadag, C.; Fischer, I.; Wever, K. E.; Chan, O. Y.; Aquarius, R.; Bartels, R. H. M. A.; Cornelius, J. F.; van Lieshout, J. H.; Boogaarts, H. D.; Kamp, M. A.
10.1101/2023.12.28.573499 — neuroscience — Posted on 2023-12-28
194 Liquid-liquid Phase Separation of Alpha-synuclein Increases the Structural Variability of Fibrils Formed during Amyloid Aggregation
Ziaunys, M.; Sulskis, D.; Veiveris, D.; Kopustas, A.; Snieckute, R.; Mikalauskaite, K.; Sakalauskas, A.; Tutkus, M.; Smirnovas, V.
10.1101/2023.12.28.573534 — biophysics — Posted on 2023-12-28
195 ADMET-AI: A machine learning ADMET platform for evaluation of large-scale chemical libraries
Swanson, K.; Walther, P.; Leitz, J.; Mukherjee, S.; Wu, J. C.; Shivnaraine, R. V.; Zou, J.
10.1101/2023.12.28.573531 — bioinformatics — Posted on 2023-12-28
201 Identification of a myofibroblast differentiation program during neonatal lung development
Yin, Y.; Koenitzer, J. R.; Patra, D.; Dietmann, S.; Bayguinov, P.; Hagan, A. S.; Ornitz, D. M.
10.1101/2023.12.28.573370 — developmental biology — Posted on 2023-12-28
202 Heterogeneous potential of human airway basal cells: Holoclone-stem cell identification in a clinical-grade system
Adamo, D.; Genna, V. G.; Galaverni, G.; Chiavelli, C.; Merra, A.; Lepore, F.; Boraldi, F.; Quaglino, D.; Evangelista, J.; Lococo, F.; Pellegrini, G.
10.1101/2023.12.28.573530 — cell biology — Posted on 2023-12-28
204 High fat diet ameliorates the mitochondrial cardiomyopathy of CHCHD10 mutant mice
Southwell, N.; Manzo, O.; Zhao, D.; Sayles, N. M.; Dash, J.; Fujita, K.; D'Aurelio, M.; Di Lorenzo, A.; Manfredi, G.; Kawamata, H.
10.1101/2023.02.22.529577 — molecular biology — Posted on 2023-12-28
205 Plant recognition by Trichoderma harzianum elicits upregulation of a novel secondary metabolite cluster required for colonization
Schalamun, M.; Li, G.; Hinterdobler, W.; Grosskinsky, D. K.; Compant, S.; Dreux-Zigha, A.; Gerke, J.; Cox, R.; Schmoll, M.
10.1101/2023.04.12.536597 — microbiology — Posted on 2023-12-28
210 Neuroprotective Effects Of VEGF-B In A Murine Model Of Aggressive Neuronal Loss With Childhood Onset
Perez-Revuelta, L.; Perez-Boyero, D.; Perez-Martin, E.; Cabedo Navarro, V. L.; Tellez de Meneses, P. G.; Weruaga, E.; Diaz, D.; Alonso, J. R.
10.1101/2023.12.28.573340 — neuroscience — Posted on 2023-12-28
212 Castration Model Illuminates Sex Differences in Healthy Aging: Insights from Metabolome and Transcriptome Analyses
Jiang, J.; Ge, N.; Wang, Y.; Qi, J.; Wen, G.; Gu, X.; Yu, X.; Shao, M.; Luo, Y.; Gu, K.; Lin, F.; Yang, S.; Wei, W.
10.1101/2023.12.27.573488 — systems biology — Posted on 2023-12-28
214 A catalogue of small proteins from the global microbiome
Duan, Y.; Santos Junior, C. D.; Schmidt, T. S. B.; Fullam, A.; de Almeida, B. L. S.; Zhu, C.; Michael, K.; Zhao, X.-M.; Bork, P.; Coelho, L. P.
10.1101/2023.12.27.573469 — bioinformatics — Posted on 2023-12-28
216 Community-based peptidomic clustering reveals pathogen-specific proteolytic signatures in wounds
Hartman, E.; Forsberg, F.; Kjellström, S.; Petrlova, J.; Luo, C.; Scott, A. M.; Puthia, M.; Malmström, J.; Schmidtchen, A.
10.1101/2023.12.28.573527 — bioinformatics — Posted on 2023-12-28
217 Discrimination of Isomeric Glycans via High-sensitive Engineered Nanopore
Yao, G.; Tian, Y.; Ke, W.; Fang, J.; Ma, S.; Li, T.; Cheng, X.; Xia, B.; Wen, L.; Gao, Z.
10.1101/2023.12.28.573513 — bioengineering — Posted on 2023-12-28
218 Common genetic variation impacts molecular stress response in the brain
Seah, C.; Singer, R.; Deans, P. M.; Bader, H.; Rusielewicz, T.; Hicks, E. M.; Young, H.; Cote, A.; Townsley, K.; Xu, C.; Hunter, C. J.; McCarthy, B.; Goldberg, J.; Dobariya, S.; Holtzherimer, P. E.; Young, K. A.; NYSCF Global Stem Cell Array Team, ; Traumatic Stress Brain Research Group, ; Noggle, S. A.; Krystal, J. H.; Paull, D.; Girgenti, M. J.; Yehuda, R.; Brennand, K.; Huckins, L.
10.1101/2023.12.27.573459 — genetics — Posted on 2023-12-28
222 Sex chromosome dominance in a UV sexual system
Vigneau, J.; Martinho, C.; Zheng, M.; Godfroy, O.; Haas, F. B.; Borg, M.; Coelho, S. M.
10.1101/2023.12.28.573518 — evolutionary biology — Posted on 2023-12-28
226 Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters
Garcia Casas, P.; Rossini, M.; Pavenius, L.; Saeed, M.; Arnst, N.; Sonda, S.; Bruzzone, M.; Berno, V.; Raimondi, A.; Sassano, M. L.; Naia, L.; Agostinis, P.; Sturlese, M.; Niemeyer, B. A.; Brismar, H.; Ankarcrona, M.; Gautier, A.; Pizzo, P.; Filadi, R.
10.1101/2023.12.28.573515 — cell biology — Posted on 2023-12-28
229 Homeostatic Dysregulation of Systemic CD8+ T Cell Compartment in Lung Cancer Patients
Lee, S.-W.; Yun, J. S.; Kim, Y. J.; Kim, H.-O.; Cho, H.-J.; Park, C.-K.; Oh, I.-J.; Cho, J.-H.
10.1101/2023.12.27.573474 — immunology — Posted on 2023-12-28
230 Phosphatases of regenerating liver balance F-actin rearrangements during T cell activation through WD repeat containing protein 1
Aguilar-Sopena, O.; Carrasco-Padilla, C.; Gomez-Moron, A.; Castro-Sanchez, P.; Estaras-Hermosel, M.; Valvo, S.; Alegre-Gomez, S.; Redondo-Munoz, J.; Torres, R.; Rodriguez-Perales, S.; Ismail, S.; Sanchez-Madrid, F.; Martin-Cofreces, N. B.; Dustin, M. L.; Navarro, P. R.
10.1101/2023.12.28.573244 — immunology — Posted on 2023-12-28
231 Bypassing Striatal Learning Mechanisms Using Delayed Feedback to Circumvent Learning Deficits in TBI
Dobryakova, E.; Tong, T. T.; Iosipchuk, O.; Lequerica, A. H.; Schneider, V.; Chiaravalloti, N. D.; Sandry, J.
10.1101/2023.12.27.573465 — neuroscience — Posted on 2023-12-28
234 GABA Increases Sensory Transmission In Monkeys
Mahrous, A. A.; Liang, L.; Balaguer, J.-M.; Ho, J. C.; Hari, K.; Grigsby, E. M.; Karapetyan, V.; Damiani, A.; Fields, D. P.; Gonzalez-Martinez, J. A.; Gerszten, P. C.; Bennett, D. J.; Heckman, C. J.; Pirondini, E.; Capogrosso, M.
10.1101/2023.12.28.573467 — neuroscience — Posted on 2023-12-28
243 Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
Sone, M.; Mitsuhashi, N.; Sugiura, Y.; Matsuoka, Y.; Maeda, R.; Yamauchi, A.; Okahashi, R.; Yamashita, J.; Sone, K.; Enju, S.; Anegawa, D.; Yamaguchi, Y.
10.1101/2023.12.27.573489 — cell biology — Posted on 2023-12-28
246 Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling ImmuneResponses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis
Ma, B.; Kamle, S.; Lee, C.-M.; Lee, J. H.; Yee, D.; Zhu, Z.; Silverman, E. K.; DeMeo, D.; Choi, A. M. K.; Lee, C. G.; Elias, J. A.
10.1101/2023.12.27.573478 — immunology — Posted on 2023-12-28
247 Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation'
Taniguchi, J.; Melani, R.; Chantranupong, L.; Wen, M. J.; Mohebi, A.; Berke, J. D.; Sabatini, B. L.; Tritsch, N. X.
10.1101/2023.12.27.573485 — neuroscience — Posted on 2023-12-28
254 From Inhibition to Excitation and Why: The Role of Temporal Urgency in Modulating Corticospinal Activity
McInnes, A. N.; Smithers, B.; Lipp, O. V.; Tresilian, J. R.; Vallence, A.-M.; Rothwell, J. C.; Marinovic, W.
10.1101/2023.12.27.573452 — neuroscience — Posted on 2023-12-28
257 Revealing the spatial characteristics of rice heat exposure in Japan through panicle temperature analysis
Toda, Y.; Ishigooka, Y.; Yoshimoto, M.; Takimoto, T.; Kuwagata, T.; Makowski, D.; Hasegawa, T.
10.1101/2023.12.26.573387 — plant biology — Posted on 2023-12-28
260 ST-GEARS: Advancing 3D Downstream Research through Accurate Spatial Information Recovery
Xia, T.; Hu, L.; Zuo, L.; Zhang, Y.; Xu, M.; Lu, Q.; Zhang, L.; Cao, L.; Pan, T.; Zhang, B.; Ma, B.; Chen, C.; Guo, J.; Shi, C.; Li, M.; Liu, C.; Li, Y.; Zhang, Y.; Fang, S.
10.1101/2023.12.09.570320 — bioinformatics — Posted on 2023-12-28
261 Chewing Through Challenges: Exploring the Evolutionary Pathways to Wood-Feeding in Insects
Beza-Beza, C. F.; Wiegmann, B. M.; Ware, J. A.; Petersen, M.; Gunter, N.; Cole, M. E.; Schwarz, M.; Bertone, M. A.; Young, D.; Mikaelyan, A.
10.1101/2023.12.27.573094 — evolutionary biology — Posted on 2023-12-28
262 Unveiling Cryptosporidium parvum Sporozoite-Derived Extracellular Vesicles: Profiling, Origin, and Protein Composition
Bertuccini, L.; Boussadia, Z.; Salzano, A. M.; Vanni, I.; Passero, I.; Nocita, E.; Scaloni, A.; Sanchez, M.; Sargiacomo, M.; Fiani, M. L.; Tosini, F.
10.1101/2023.12.21.571703 — microbiology — Posted on 2023-12-28
264 FMRP regulates tangential neuronal migration via MAP1B
Messaoudi, S.; Allam, A.; Stoufflet, J.; Paillard, T.; Le Ven, A.; Fouquet, C.; Doulazmi, M.; Trembleau, A.; Caille, I.
10.1101/2023.03.06.530447 — neuroscience — Posted on 2023-12-28
265 Abscisic acid signaling gates salt-specific responses of plant roots
Lamers, J.; Zhang, Y.; van Zelm, E.; Meyer, A. J.; De Zeeuw, T.; Verstappen, F.; Veen, M.; Deolu-Ajayi, A. O.; Gommers, C. M. M.; Testerink, C.
10.1101/2023.12.28.572987 — plant biology — Posted on 2023-12-28
266 Aberrant connective tissue sheath contraction drives premature hair follicle regression by inducing progenitor cell depletion in androgenetic alopecia
Deng, Z.; Yang, L.; Duan, S.; Chen, M.; Zhang, Y.; Liu, F.; Tang, Y.; Wang, Y.; Li, J.; Xu, S.; Wu, Z.; Wang, B.; Zhao, Z.; Shi, W.; Xie, H.; Li, G.; Li, J.
10.1101/2023.12.25.573294 — pathology — Posted on 2023-12-28
267 Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis
Colazo, J. M.; Hoogenboezem, E. N.; Keech, M. C.; Francini, N.; Shah, V.; Yu, F.; Lo, J. H.; Sorets, A. G.; McCune, J. T.; Cho, H.; DeJulius, C. R.; Michell, D. L.; Maerz, T.; Vickers, K. C.; Gibson-Corley, K. N.; Hasty, K. A.; Crofford, L.; Cook, R. S.; Duvall, C. L.
10.1101/2023.05.31.542971 — bioengineering — Posted on 2023-12-28
269 Quantifying microbial guilds
Rivas-Santisteban, J.; Yubero, P.; Robaina-Estevez, S.; Gonzalez, J. M.; Tamames, J.; Pedros-Alio, C.
10.1101/2023.07.23.550202 — ecology — Posted on 2023-12-28
270 Microscopy-guided subcellular proteomic discovery by high-speed ultra-content photo-biotinylation
Chen, Y.-D.; Chang, C.-W.; Cheung, C. H. Y.; Chang, H.-J.; Sie, Y.-D.; Chung, C.-W.; Huang, C.-K.; Huang, C.-C.; Chong, W. M.; Liu, Y.-P.; Lin, Y.-C.; Kai, H.-J. J.; Wang, P.-J.; Liao, J.-C.
10.1101/2023.12.27.573388 — cell biology — Posted on 2023-12-28
271 Identifying Discrepancies in HIV Infectivity and Virion Maturation Using FRET-Based Detection and Quantification
Narayan, K.; Choi, J.; Gujar, S. S.; McGraw, A.; Tibebe, H.; Bose, L. M.; Arnette, C. N.; Izumi, T.
10.1101/2023.12.25.573317 — microbiology — Posted on 2023-12-28
272 The effects of data leakage on connectome-based machine learning models
Rosenblatt, M.; Tejavibulya, L.; Jiang, R.; Noble, S.; Scheinost, D.
10.1101/2023.06.09.544383 — neuroscience — Posted on 2023-12-28
274 Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
Dolcemascolo, R.; Heras-Herandez, M.; Goiriz, L.; Montagud-Martinez, R.; Requena-Menendez, A.; Ruiz, R.; Perez-Rafols, A.; Higuera-Rodriguez, R. A.; Perez-Ropero, G.; Vranken, W. F.; Martelli, T.; Kaiser, W.; Buijs, J.; Rodrigo, G.
10.1101/2022.11.22.516435 — synthetic biology — Posted on 2023-12-28
275 Improving genome-scale metabolic models of incomplete genomes with deep learning
Boer, M. D.; Melkonian, C.; Haas, A. F.; Zeiforopoulos, H.; Garza, D.; Dutilh, B. E.
10.1101/2023.07.10.548314 — bioinformatics — Posted on 2023-12-28
278 WITHDRAWN: I feel your pain: Higher empathy is associated with higher posterior default mode network activity
Oliva, V.; Riegner, G.; Dean, J.; Khatib, L.; Allen, A.; Barrows, D.; Chen, C.; Fuentes, R.; Jacobson, A.; Lopez, C.; Mosbey, D.; Reyes, M.; Ross, J.; Uvarova, A.; Liu, T.; Zeidan, F.
10.1101/2023.08.11.553004 — neuroscience — Posted on 2023-12-28
280 Evidence that metastases arise de novo as new cancers from cells of target organs
Raghuram, G. V.; Pal, K.; Shende, S.; Khare, N. K.; Jadhav, V.; Shinde, S.; Prasad, R.; Wani, H.; Mittra, I.
10.1101/2023.08.09.552586 — cancer biology — Posted on 2023-12-27
282 The systematic assessment of completeness of public metadata accompanying omics studies
Huang, Y.-N.; Jaiswal, P. V.; Rajesh, A.; Yadav, A.; Yu, D.; Liu, F.; Scheg, G.; Boldirev, G.; Nakashidze, I.; Mehta, J. H.; Wang, K.; Patel, K. K.; Sarkar, A.; Mirza, M. A. B.; Hu, J.; Peng, Q.; Hapani, K. C.; Ayyala, R.; Guo, R.; Wong, M. Y.; Kapur, S.; Ramesh, T.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2021.11.22.469640 — bioinformatics — Posted on 2023-12-27
284 Hypoxia Sensing in Resident Cardiac Macrophages Regulates the Arg1 Macrophage Lineage During Ischemic Heart Injury
Kadyrov, F. F.; Koenig, A. L.; Amrute, J. M.; Dun, H.; Li, W.; Weinheimer, C. J.; Nigro, J. M.; Kovacs, A.; Bredemeyer, A. L.; Lai, L.; Kopecky, B. J.; Penna, V.; Kreisel, D.; Lavine, K. J.
10.1101/2022.08.04.502542 — immunology — Posted on 2023-12-27
286 Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology
Gazula, H.; Tregidgo, H.; Billot, B.; Balbastre, Y.; Williams-Ramirez, J.; Herisse, R.; Deden-Binder, L. J.; Casamitjana, A.; Melief, E. J.; Latimer, C. S.; Kilgore, M. D.; Montine, M.; Robinson, E.; Blackburn, E.; Marshall, M. S.; Connors, T. R.; Oakley, D. H.; Frosh, M. P.; Young, S. I.; Van Leemput, K.; Dalca, A. V.; Fischl, B.; Mac Donald, C. L.; Keene, C. D.; Hyman, B.; Iglesias, J. E.
10.1101/2023.06.08.544050 — neuroscience — Posted on 2023-12-27
289 In-utero exposure to estrogen-mimicking bisphenols alters bone mineralization in the offspring
Varma, S.; Molangiri, A.; Mudavath, S.; Ananthan, R.; Rajanna, A.; Duttaroy, A. K.; Basak, S.
10.1101/2023.12.27.573412 — developmental biology — Posted on 2023-12-27
291 Macrophages undergo functionally significant reprograming of nucleotide metabolism upon classical activation
John, S. V.; Seim, G. L.; Erazo-Flores, B. J.; Steill, J.; Freeman, J.; Votava, J. A.; Arp, N. L.; Qing, X.; Stewart, R.; Knoll, L. J.; Fan, J.
10.1101/2023.12.27.573447 — cell biology — Posted on 2023-12-27
294 A Framework to Determine Active Connectivity within the Mouse Brain
Sun, G.; Mano, T.; Shi, S.; Li, A.; Ode, K.; Rosi-Andersen, A.; Brown, S. A.; Ueda, H.; Kompotis, K.; Forger, D. B.
10.1101/2023.12.27.573396 — neuroscience — Posted on 2023-12-27
296 Is there a neural common factor for visual illusions?
Jastrzebowska, M. A.; Ozkirli, A.; Cretenoud, A. F.; Draganski, B.; Herzog, M. H.
10.1101/2023.12.27.573437 — neuroscience — Posted on 2023-12-27
297 Constitutive and conditional epitope-tagging of endogenous G protein coupled receptors in Drosophila
Bonanno, S. L.; Sanfilippo, P.; Eamani, A.; Sampson, M.; Binu, K.; Li, K.; Burns, G.; Makar, M. M.; Zipursky, S. L.; Krantz, D. E.
10.1101/2023.12.27.573472 — neuroscience — Posted on 2023-12-27
299 Proliferating CLL cells express high levels of CXCR4 and CD5
Friedman, D.; Mehtani, D. P.; Vidler, J. B.; Patten, P. E.; Hoogeboom, R.
10.1101/2023.12.27.573410 — cancer biology — Posted on 2023-12-27
300 Optical manipulation reveals macrophage mediated mesoscale brain mechanical homeostasis in vivo
So, W. Y.; Johnson, B.; Gordon, P. B.; Bishop, K. S.; Gong, H.; Burr, H. A.; Staunton, J. R.; Handler, C.; Sood, R.; Scarcelli, G.; Tanner, K.
10.1101/2023.12.27.573380 — biophysics — Posted on 2023-12-27
303 Towards a Brighter Constellation: Multi-Organ Neuroimaging of Neural and Vascular Dynamics in the Spinal Cord and Brain
Celinskis, D.; Black, C. J.; Murphy, J.; Barrios-Anderson, A.; Friedman, N.; Shaner, N. C.; Saab, C.; Gomez-Ramirez, M.; Lipscombe, D.; Borton, D. A.; Moore, C. I.
10.1101/2023.12.25.573323 — bioengineering — Posted on 2023-12-27
304 Potential clinical value and influence of conductivity in conductive cardiac patches for reducing post-MI arrythmia risks
Miao, Y.; Fu, Z.; Zhang, J.; Tao, Y.; Pang, K.; Wang, C.; Jiang, Q.; Shen, L.; Xia, T.; Lu, P.; Xu, Z.; Xia, L.; Zuo, L.; Song, J.; Gao, C.; Deng, D.; Jiang, R.; Zhu, Y.
10.1101/2023.12.27.573394 — bioengineering — Posted on 2023-12-27
306 TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43.
Godoy-Corchuelo, J. M.; Ali, Z.; Brito Armas, J. M.; Martins-Bach, A. B.; Garcia-Toledo, I.; Fernandez-Beltran, L. C.; Lopez-Carbonero, J. I.; Bascunana, P.; Spring, S.; Jimenez-Coca, I.; Munoz de Bustillo Alfaro, R. A.; Sanchez-Barrena, M. J.; Nair, R. R.; Nieman, B. J.; Lerch, J. P.; Miller, K. L.; Ozdinler, H.; Fisher, E.; Cunningham, T. J.; Acevedo-Arozena, A.; Corrochano, S.
10.1101/2023.12.27.573393 — neuroscience — Posted on 2023-12-27
308 Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma
Kroeze, E.; Iaccarino, I.; Kleisman, M. M.; Mondal, M.; Beder, T.; Khouja, M.; Hoeppner, M. P.; Scheijde-Vermeulen, M.; Kester, L. A.; Brueggemann, M.; Baldus, C. D.; Cario, G.; Bladergroen, R. S.; Garnier, N.; Attarbaschi, A.; Verdu-Amoros, J. J.; Sutton, R.; MacIntyre, E.; Scholten, K.; Padilla, L. A.; Burkhardt, B.; Beishuizen, A.; den Boer, M. L.; Kuiper, R. P.; Loeffen, J. L.; Boer, J. M.; Klapper, W.
10.1101/2023.12.27.573433 — cancer biology — Posted on 2023-12-27
309 Precise single-cell transcriptomic mapping of normal and leukemic cell states reveals unconventional lineage priming in acute myeloid leukemia
Zeng, A. G. X.; Iacobucci, I.; Shah, S.; Mitchell, A.; Wong, G.; Bansal, S.; Gao, Q.; Kim, H.; Kennedy, J. A.; Minden, M. D.; Haferlach, T.; Mullighan, C. G.; Dick, J. E.
10.1101/2023.12.26.573390 — cancer biology — Posted on 2023-12-27
312 p75NTR neurotrophin receptor function is redundant for development, growth and fertility in the rat.
Meek, S.; Singh-Dolt, K.; Sutherland, L.; Sharp, M. G. F.; Del-Pozo, J.; Walker, D.; Burdon, T.
10.1101/2023.12.27.573424 — genetics — Posted on 2023-12-27
316 Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro
Vysochinskaya, V.; Zabrodskaya, Y.; Dovbysh, O.; Emelyanov, A.; Klimenko, V.; Knyazev, N.; Terterov, I.; Egorova, M.; Bogdanov, A.; Maslov, M.; Vasin, A.; Dubina, M.
10.1101/2023.12.27.573407 — molecular biology — Posted on 2023-12-27
318 SIK2: A novel negative feedback regulator of FGF signaling
Kuser-Abali, G.; Ugurlu-Bayarslan, A.; Yilmaz, Y.; Ozcan, F.; Karaer, F.; Bugra, K.
10.1101/2023.12.26.573381 — molecular biology — Posted on 2023-12-27
320 Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells
Raposo, A. A. S. F.; Rosmaninho, P.; Silva, S. L.; Paco, S.; Brazao, M. E.; Godinho-Santos, A.; Tokunaga-Mizoro, Y.; Nunes-Cabaco, H.; Serra-Caetano, A.; Almeida, A. R. M.; Sousa, A. E.
10.1101/2023.12.27.573411 — immunology — Posted on 2023-12-27
321 Intranasal Delivery of shRNA to Knockdown the 5HT-2A Receptor Enhances Memory and Alleviates Anxiety
Rohn, T. T.; Radin, D.; Brandmeyer, T.; Seidler, P. G.; Linder, B. J.; Lytle, T.; Mee, J. L.; Macciardi, F.
10.1101/2023.12.27.573449 — neuroscience — Posted on 2023-12-27
322 The Primary Cilium and its Hedgehog Signaling in Nociceptors Contribute to Inflammatory and Neuropathic Pain
Fitzsimons, L. A.; Staurengo-Ferrari, L.; Bogen, O.; Araldi, D.; Bonet, I. J. M.; Jordan, E. E.; Levine, J. D.; Tucker, K. L.
10.1101/2023.12.27.573420 — neuroscience — Posted on 2023-12-27
328 The placental protein NRK promotes cell death through its plasma membrane-localizing CNH domain
Lestari, B.; Soda, K.; Moritsugu, K.; Kidera, A.; Suenaga, Y.; Hippo, Y.; Meiyanto, E.; Komada, M.; Wahyuningsih, M. S. H.; Fukushima, T.
10.1101/2023.12.27.573405 — cell biology — Posted on 2023-12-27
329 Structure of the hepatitis C virus E1/E2 envelope proteins in a homodimeric complex
Augestad, E.; Olesen, C. H.; Groenberg, C.; Soerensen, A.; Velazquez-Moctezuma, R.; Fanalista, M.; Bukh, J.; Wang, K.; Gourdon, P.; Prentoe, J.
10.1101/2023.12.27.573427 — molecular biology — Posted on 2023-12-27
330 Multi-Omics Analysis Of Antiviral Interactions Of Elizabethkingia anophelis And Zika Virus
Omme, S. F.; Wang, J.; Sifuna, M.; Rodriguez, J.; Owusu, R.; Goli, M.; Jiang, P.; Purba, W.; Nwaiwu, J.; Brelsfoard, C.; Vigneron, A.; Kramer, L.; Ciota, A.; Mechref, Y.; Onyango, M. G.
10.1101/2023.12.27.573398 — microbiology — Posted on 2023-12-27
332 Local adaptation to mercury contamination by nitrogen-fixing rhizobia is driven by horizontal gene transfer, copy number, and enhanced gene expression
Bhat, A.; Sharma, R.; Lucas, M. M.; Desigan, K.; Clear, M.; Mishra, A.; Bowers, R.; Woyke, T.; Epstein, B.; Tiffin, P.; Pueyo, J. J.; Paape, T.
10.1101/2023.12.27.573466 — microbiology — Posted on 2023-12-27
335 Structure-based discovery of positive allosteric modulators for the calcium sensing receptor
Liu, F.; Wu, C.-G.; Tu, C.-L.; Glenn, I.; Meyerowitz, J.; Kaplan, A. L.; Lyu, J.; Cheng, Z.; Tarkhanova, O. O.; Moroz, Y. S.; Irwin, J. J.; Chang, W.; Shoichet, B. K.; Skiniotis, G.
10.1101/2023.12.27.573448 — biophysics — Posted on 2023-12-27
336 S1 hydrophobic residues alter the voltage sensing phosphatase enzymatic function and voltage sensing
Rayaprolu, V.; Miettinen, H. M.; Baker, W.; Fisher, M.; Mueller, G.; Rankin, W. O.; Kelley, J. J.; Ratzan, W.; Leong, L. M.; Davisson, J. A.; Baker, B. J.; Kohout, S. C.
10.1101/2023.12.27.573443 — biophysics — Posted on 2023-12-27
339 Chemical probes to interrogate the extreme environment of mosquito larval guts
Guzman, L. E.; Wijetunge, A. N.; Riske, B. F.; Massani, B. B.; Riehle, M. A.; Jewett, J. C.
10.1101/2023.12.27.573438 — biochemistry — Posted on 2023-12-27
341 Genomic evidence for hybridization and introgression between blue peafowl and green peafowl and selection for white plumage
Wang, G.; Ban, L.; Zhang, X.; Zhao, X.; Ren, X.; Chen, A.; Zhang, L.; Lu, Y.; Jiang, Z.; Zhao, X.; Wen, J.; Zhang, Y.; Cheng, X.; Wang, H.; Dai, W.; Liu, Y.; Ning, Z.; Qu, L.
10.1101/2023.12.27.573425 — genomics — Posted on 2023-12-27
342 Comparative genomics of Cryptococcus and Kwoniella reveals pathogenesis evolution and contrasting modes of karyotype evolution via chromosome fusion or intercentromeric recombination
Coelho, M. A.; David-Palma, M.; Shea, T.; Bowers, K.; McGinley-Smith, S.; Mohammad, A. W.; Gnirke, A.; Yurkov, A. M.; Nowrousian, M.; Sun, S.; Cuomo, C. A.; Heitman, J.
10.1101/2023.12.27.573464 — genomics — Posted on 2023-12-27
343 The genetic consequences of population marginality: a case study in maritime pine
THERAROZ, A.; GUADANO-PEYROT, C.; Archambeau, J.; PINOSIO, S.; BAGNOLI, F.; PIOTTI, A.; AVANZI, C.; VENDRAMIN, G. G.; ALIA, R.; GRIVET, D.; WESTERGREN, M.; GONZALEZ-MARTINEZ, S. C.
10.1101/2023.12.27.573436 — genetics — Posted on 2023-12-27
345 The Statistical Building Blocks of Animal Movement Simulations
Getz, W. M.; Salter, R.; Sethi, V.; Cain, S.; Nathan, R.; Spiegel, O.; Toledo, S.
10.1101/2023.12.27.573450 — ecology — Posted on 2023-12-27
350 Experience shapes initial exploration for non-generalizable spatial learning
Awh, M. P.; Latimer, K. W.; Zhou, N.; Leveroni, Z. M.; Stephens, Z. M.; Yu, J. Y.
10.1101/2023.12.26.573368 — neuroscience — Posted on 2023-12-27
351 TRPM8-dependent shaking in mammals and birds
Selescu, T.; Bivoleanu, R.-A.; Iodi Carstens, M.; Manolache, A.; Caragea, V.-M.; Hutanu, D.-E.; Meerupally, R.; Wei, E. T.; Carstens, E.; Zimmermann, K.; Babes, A.
10.1101/2023.12.27.573364 — physiology — Posted on 2023-12-27
355 Effects of sampling methodology on phenology indices: insights from sites across India and modelling
Tiruvaimozhi, Y.; Teegalapalli, K.; Reddy, A.; Murali, A.; Datta, A.; Krishnan, A.; Ratnam, J.; Sankaran, M.; Ongole, S.; Kasinathan, S.; Raman, T. R. S.; Ramaswami, G.
10.1101/2023.12.26.573352 — ecology — Posted on 2023-12-27
356 Microscopy-guided subcellular proteomic discovery by high-speed ultra-content photo-biotinylation
Liao, J.-C.; Chen, Y.-D.; Chang, C.-W.; Cheung, C. H. Y.; Chang, H.-J.; Sie, Y.-D.; Chung, C.-W.; Huang, C.-K.; Huang, C.-C.; Chong, W. M.; Liu, Y.-P.; Lin, Y.-C.; Kai, H.-J. J.; Wang, P.-J.
10.1101/2023.12.27.573388 — cell biology — Posted on 2023-12-27
357 Maf1 phosphorylation is regulated through the action of prefoldin-like Bud27 on PP4 phosphatase in Saccharomyces cerevisiae
Guiterrez-Santiago, F.; Martinez-Fernandez, V.; Garrido-Godino, A.; Colino-Palomino, C.; Clemente-Blanco, A.; Conesa, C.; Acker, J.; Navarro, F.
10.1101/2023.12.20.572514 — molecular biology — Posted on 2023-12-27
360 Aberrant connective tissue sheath contraction drives premature hair follicle regression by inducing progenitor cell depletion in androgenetic alopecia
Deng, Z.; Yang, L.; Duan, S.; Chen, M.; Zhang, Y.; Liu, F.; Tang, Y.; Wang, Y.; Li, J.; Xu, S.; Wu, Z.; Wang, B.; Zhao, Z.; Shi, W.; Xie, H.; Li, G.; Li, J.
10.1101/2023.12.25.573294 — pathology — Posted on 2023-12-27
361 Optimal distance metrics for single-cell RNA-seq populations
Ji, Y.; Green, T.; Peidli, S.; Bahrami, M.; Liu, M.; Zappia, L.; Hrovatin, K.; Sander, C.; Theis, F.
10.1101/2023.12.26.572833 — bioinformatics — Posted on 2023-12-27
362 Alternate routes to mnm5s2U synthesis in Gram-positive bacteria
Jaroch, M.; Sun, G.; Tsui, H.-C. T.; Reed, C.; Sun, J.; Joerg, M.; Winkler, M. E.; Rice, K. C.; Stich, T. A.; Dedon, P.; Dos Santos, P. C.; de Crecy-Lagard, V.
10.1101/2023.12.21.572861 — microbiology — Posted on 2023-12-27
363 Associations between COVID-19 and putative markers of neuroinflammation: A diffusion basis spectrum imaging study.
Zhang, W.; Gorelik, A. J.; Wang, Q.; Norton, S. A.; Hershey, T.; Agrawal, A.; Bijsterbosch, J. D.; Bogdan, R.
10.1101/2023.07.20.549891 — neuroscience — Posted on 2023-12-27
364 Motion Impact Score for Detecting Spurious Brain-Behavior Associations
Kay, B. P.; Montez, D. F.; Marek, S.; Tervo-Clemmens, B.; Siegel, J. S.; Adeyemo, B.; Laumann, T. O.; Metoki, A.; Chauvin, R. J.; Van, A. N.; Suljic, V.; Krimmel, S. R.; Miller, R.; Newbold, D. J.; Zheng, A.; Seider, N. A.; Scheidter, K. M.; Monk, J.; Feczko, E. J.; Randolph, A.; Miranda-Dominguez, O.; Moore, L. A.; Perrone, A. J.; Conan, G. M.; Earl, E. A.; Malone, S. M.; Cordova, M.; Doyle, O.; Lynch, B. J.; Wilgenbusch, J. C.; Pengo, T.; Graham, A. M.; Roland, J. L.; Gordon, E. M.; Snyder, A. Z.; Barch, D.; Fair, D. A.; Dosenbach, N. U.
10.1101/2022.12.16.520797 — neuroscience — Posted on 2023-12-27
365 Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock
Tariq, D.; Maurici, N.; Bartholomai, B.; Chandrasekaran, S.; Dunlap, J. C.; Bah, A.; CRANE, B. R.
10.1101/2022.11.03.515097 — biochemistry — Posted on 2023-12-27
366 Neural circuit models for evidence accumulation through choice-selective sequences
Brown, L. S.; Cho, J. R.; Bolkan, S. S.; Nieh, E. H.; Schottdorf, M.; Tank, D. W.; Brody, C. D.; Witten, I. B.; Goldman, M. S.
10.1101/2023.09.01.555612 — neuroscience — Posted on 2023-12-27
367 Arbuscular mycorrhizal fungus Rhizophagus irregularis expresses an outwardly Shaker-like channel involved in rice potassium nutrition
Corratge-Faillie, C.; Matic, L.; Chmaiss, L.; Zhour, H.; Lolivier, J.-P.; Audebert, P.-A.; Bui, T. X.; Seck, M.; Chinachanta, K.; Fizames, C.; Wipf, D.; Sentenac, H.; Very, A.-A.; Courty, P.-E.; Luu, D. T.
10.1101/2022.11.04.515200 — plant biology — Posted on 2023-12-27
370 Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target
Wazir, S.; Parviainen, T. A. O.; Maksimainen, M. M.; Duong, M. T. H.; Pfannenstiel, J. J.; Cluff, D.; Sowa, S. T.; Galera-Prat, A.; Ferraris, D. V.; Fehr, A.; Heiskanen, J. P.; Lehtiö, L.
10.1101/2023.08.28.555062 — biochemistry — Posted on 2023-12-27
371 Unveiling Cryptosporidium parvum Sporozoite-Derived Extracellular Vesicles: Profiling, Origin, and Protein Composition
Bertuccini, L.; Boussadia, Z.; Salzano, A. M.; Vanni, I.; Passero, I.; Nocita, E.; Scaloni, A.; Sanchez, M.; Sargiacomo, M.; Fiani, M. L.; Tosini, F.
10.1101/2023.12.21.571703 — microbiology — Posted on 2023-12-27
372 Impaired activation of the prefrontal executive network during working memory processing in multiple sclerosis
Rossi, C.; Vidaurre, D.; Costers, L.; D'hooghe, M.; Akbarian, F.; D'haeseleer, M.; Woolrich, M.; Nagels, G.; Van Schependom, J.
10.1101/2023.12.22.573051 — neuroscience — Posted on 2023-12-27
373 Mouse helpers ensure maternal-infant survival
Schuster, L.; Henderson, R.; Caslin, A.; Kaur, G.; Sankar, S.; Ananth, D.; Kirk, M.; Leone, P.; Adolph, K. E.; Froemke, R. C.; Mar, A.
10.1101/2022.12.26.521927 — neuroscience — Posted on 2023-12-27
377 Evolutionary trends of alternative splicing
de la Fuente, R.; Diaz-Villanueva, W.; Arnau, V.; Moya, A.
10.1101/2023.12.26.571677 — evolutionary biology — Posted on 2023-12-27
378 Nitrogen availability and TOR signalling are important for preventing catastrophic mitosis in fission yeast
Zemlianski, V.; Maresova, A.; Princova, J.; Holic, R.; Häsler, R.; Ramos del Rio, M. J.; Lhoste, L.; Zarechyntsava, M.; Prevorovsky, M.
10.1101/2023.12.25.573293 — cell biology — Posted on 2023-12-27
379 Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism
Choi, A.; Smith, J.; Wang, Y.; Shin, H.; Kim, B.; Wiest, A.; Jin, X.; An, I.; Hong, J.; Antila, H.; Thomas, S.; Bhattarai, J. P.; Beier, K.; Ma, M.; Weber, F.; Chung, S.
10.1101/2023.12.26.573156 — neuroscience — Posted on 2023-12-27
385 Generating single-cell gene expression profiles for high-resolution spatial transcriptomics based on cell boundary images
Zhang, B.; Li, M.; Kang, Q.; Deng, Z.; Qin, H.; Su, K.; Feng, X.; Chen, L.; Liu, H.; Fang, S.; Zhang, Y.; Li, Y.; Brix, S.; Xu, X.
10.1101/2023.12.25.573324 — bioinformatics — Posted on 2023-12-26
389 MERITS: a web-based integrated MycobacterialPE/PPE protein database
He, Z.; Wang, C.; Guo, X.; Sun, H.; Bi, Y.; Pitt, M. E.; Li, C.; Song, J.; Coin, L. J.; Li, F.
10.1101/2023.12.26.573374 — bioinformatics — Posted on 2023-12-26
397 Orphan nuclear receptor NR2E3 and its small-molecule agonist induce cancer cell apoptosis through regulating p53, IFNα and MYC pathways
Wang, Y.; Kroll, T.; Hao, L.; Sharma, A.; Zhou, V.; Moat, L.; Mayer, J.; Shukla, S. S.; Hebbring, S.; Guo, S.; Iden, M.; Bissonnette, A.; Ananiev, G.; Parashar, D.; Rader, J. S.; Janz, S.; Wen, Z.
10.1101/2023.12.26.573366 — cancer biology — Posted on 2023-12-26
402 The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota
Kulalert, W.; Wells, A. C.; Link, V. M.; Lim, A. I.; Bouladoux, N.; Nagai, M.; Harrison, O. J.; Kamenyeva, O.; Kabat, J.; Enamorado, M.; Chiu, I.; Belkaid, Y.
10.1101/2023.12.26.573358 — immunology — Posted on 2023-12-26
403 Single nucleus RNA sequencing reveals glial cell type-specific responses to ischemic stroke
Bormann, D.; Knoflach, M.; Poreba, E.; Riedl, C. J.; Testa, G.; Orset, C.; Levilly, A.; Cottereau, A.; Jauk, P.; Hametner, S.; Golabi, B.; Copic, D.; Klas, K.; Direder, M.; Kuehtreiber, H.; Salek, M.; zur Nedden, S.; Baier-Bitterlich, G.; Kiechl, S.; Haider, C.; Endmayr, V.; Hoeftberger, R.; Ankersmit, H. J.; Mildner, M.
10.1101/2023.12.26.573302 — neuroscience — Posted on 2023-12-26
404 Feeding-state dependent modulation of reciprocally interconnected inhibitory neurons biases sensorimotor decisions in Drosophila
de Tredern, E.; Manceau, D.; Blanc, A.; Sakagiannis, P.; Barre, C.; Sus, V.; Viscido, F.; Hasan, M. A.; Autran, S.; Nawrot, M.; Masson, J.-B.; Jovanic, T.
10.1101/2023.12.26.573306 — neuroscience — Posted on 2023-12-26
405 Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView
Kudo, T.; Meireles, A. M.; Moncada, R.; Chen, Y.; Wu, P.; Gould, J.; Hu, X.; Kornfeld, O.; Jesudason, R.; Foo, C.; Hockendorf, B.; Bravo, H. C.; Town, J. P.; Wei, R.; Rios, A.; Chandrasekar, V.; Heinlein, M.; Cai, S.; Lu, C. S.; Celen, C.; Kljavin, N.; Jiang, J.; Hleap, J. S.; Kayagaki, N.; Melo, F. d. S. e.; McGinnis, L.; Li, B.; Singh, A.; Garraway, L.; Rozenblatt-Rosen, O.; Regev, A.; Lubeck, E.
10.1101/2023.12.26.573143 — systems biology — Posted on 2023-12-26
406 Rationally designed modular STAT-activating scaffolds enforce cell-intrinsic transcriptional programs augmenting the anti-tumor potency of CAR T cells
Saxby, C. P.; Ishida, T. K.; Rosser, J. M.; Curtis, B. C.; Baldwin, M. L.; Spurrell, C. H.; Giles, J.; Valdez, A.; Johnson, A. J.; Gustafson, J.; Appelbaum, J. S.; Jensen, M. C.
10.1101/2023.12.22.573170 — bioengineering — Posted on 2023-12-26
408 CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue
Gu, J.; Iyer, A.; Wesley, B.; Taglialatela, A.; Leuzzi, G.; Hangai, S.; Decker, A.; Gu, R.; Klickstein, N.; Shuai, Y.; Jankovic, K.; Parker-Burns, L.; Jin, Y.; Zhang, J. Y.; Hong, J.; Niu, X.; Chou, J.; Landau, D. A.; Azizi, E.; Chan, E. M.; Ciccia, A.; Gaublomme, J. T.
10.1101/2023.12.26.572587 — genomics — Posted on 2023-12-26
411 Mitochondrial dysfunction and mitophagy blockade contribute to renal osteodystrophy in chronic kidney disease-mineral bone disorder
Hsu, S.-N.; Stephen, L. A.; Phadwal, K.; Dillon, S.; Carter, R. N.; Morton, N. M.; Luijten, I.; Emelianova, K.; Amin, A. K.; Macrae, V. E.; Freeman, T. C.; Staines, K. A.; Farquharson, C.
10.1101/2023.12.26.573355 — genomics — Posted on 2023-12-26
412 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease
Lobato-Moreno, S.; Yildiz, U.; Claringbould, A.; Servaas, N. H.; Vlachou, E. P.; Arnold, C.; Bauersachs, H. G.; Campos-Fornes, V.; Prummel, K. D.; Noh, K. M.; Marttinen, M.; Zaugg, J. B.
10.1101/2023.12.26.573253 — genomics — Posted on 2023-12-26
419 Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil
Chatterjee, S.; Naeli, P.; Simms, N.; Garzia, A.; Hackett, A.; Coyle, K.; Harris Snell, P.; McGirr, T.; Sawant, T. N.; Dang, K.; Stoichkova, Z. V.; Alain, T.; Tuschl, T.; McDade, S. S.; Longley, D.; Gkogkas, C. G.; Adrain, C.; Knight, J. R. P.; Jafarnejad, S. M.
10.1101/2023.12.26.573247 — cell biology — Posted on 2023-12-26
420 Ventilation does not affect influenza virus transmission efficiency in a ferret playpen setup
Rockey, N. C.; Le Sage, V.; Shephard, M.; Vargas-Maldonado, N.; French, A. J.; Walter, S.; Ferreri, L. M.; Holmes, K. E.; VanInsberghe, D.; Clack, H.; Prussin, A. J.; Lowen, A. C.; Marr, L.; Lakdawala, S.
10.1101/2023.12.26.573248 — microbiology — Posted on 2023-12-26
421 Association between the oral microbiome and brain resting state connectivity in schizophrenia
Lin, D.; Fu, Z.; Liu, J.; Perrone-Bizzozero, N.; Hutchison, K. E.; Bustillo, J.; Du, Y.; Pearlson, G.; Calhoun, V. D.
10.1101/2023.12.22.573165 — microbiology — Posted on 2023-12-26
422 Identifying Discrepancies in HIV Infectivity and Virion Maturation Using FRET-Based Detection and Quantification
Narayan, K.; Choi, J.; Gujar, S. S.; McGraw, A.; Tibebe, H.; Bose, L. M.; Arnette, C. N.; Izumi, T.
10.1101/2023.12.25.573317 — microbiology — Posted on 2023-12-26
423 TMEM41B is an endoplasmic reticulum Ca2+ release channel maintaining T cell metabolic quiescence and responsiveness
ying, M. y.; yi, W.; cui, Z. x.; gang, J.; jing, X.; yang, L. z.; na, Y.; bing, G. z.; qing, X. b.; min, P.
10.1101/2023.12.25.573330 — immunology — Posted on 2023-12-26
426 Sequence-specific interactions determine viscoelasticity and aging dynamics of protein condensates
Alshareedah, I.; Borcherds, W. M.; Cohen, S. R.; Singh, A.; Posey, A. E.; Farag, M.; Bremer, A.; Strout, G. W.; Tomares, D. T.; Pappu, R. V.; Mittag, T.; Banerjee, P. R.
10.1101/2023.04.06.535902 — biophysics — Posted on 2023-12-26
427 Structure-function relationships of mucociliary clearance in the human airways
Roth, D.; Sahin, A. T.; Ling, F.; Senger, C.; Quiroz, E.; Calvert, B.; van der Does, A.; Güney, T. G.; Tepho, N.; Glasl, S.; van Schadewijk, A.; von Schledorn, L.; Olmer, R.; Kanso, E.; Nawroth, J. C.; Ryan, A. L.
10.1101/2023.12.24.572054 — biophysics — Posted on 2023-12-26
428 Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction
Mikhajlov, O.; Adar, R. M.; Tatulea-Codrean, M.; Mace, A.-S.; Manzi, J.; Tabarin, F.; Battistella, A.; Di Federico, F.; Joanny, J.-F.; Tran van Nhieu, G.; Bassereau, P.
10.1101/2022.09.12.507658 — cell biology — Posted on 2023-12-26
429 The Hierarchy of Psychedelic Effects: Three Systematic Reviews and Meta-Analyses
Shinozuka, K.; Jerotic, K.; Mediano, P. A. M.; Zhao, A. T.; Preller, K. H.; Carhart-Harris, R. L.; Kringelbach, M. L.
10.1101/2023.10.06.561183 — neuroscience — Posted on 2023-12-26
431 TaNF-Y-PRC2 orchestrates temporal control of starch and protein synthesis in wheat
Chen, J.; Zhao, L.; Li, H.; Yang, C.; Wang, D.; Lin, X.; Lin, Y.; Zhang, H.; Bie, X.; Zhao, P.; Xu, S.; Zhang, X.; Zhang, X.; Yao, Y.; Xiao, J.
10.1101/2023.12.26.573020 — plant biology — Posted on 2023-12-26
433 CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing.
Felgines, L.; Rymen, B.; Martins, L. M.; Xu, G.; Matteoli, C.; Himber, C.; Zhou, M.; Eis, J.; Coruh, C.; Böhrer, M.; Kuhn, L.; Chicher, J.; Pandey, V.; Hammann, P.; Wohlschlegel, J.; Waltz, F.; Law, J. A.; Blevins, T.
10.1101/2023.12.26.573199 — molecular biology — Posted on 2023-12-26
434 Viral expansion after transfer is a primary driver of influenza A virus transmission bottlenecks
Holmes, K. E.; VanInsberghe, D.; Ferreri, L. M.; Elie, B.; Ganti, K.; Lee, C.-Y.; Lowen, A. C.
10.1101/2023.11.19.567585 — microbiology — Posted on 2023-12-26
436 Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation
Hayashi, T.; Sadaki, S.; Tsuji, R.; Okada, R.; Fuseya, S.; Kanai, M.; Nakamura, A.; Okamura, Y.; Muratani, M.; Wenchao, G.; Sugasawa, T.; Mizuno, S.; Warabi, E.; Kudo, T.; Takahashi, S.; Fujita, R.
10.1101/2023.12.25.570044 — cell biology — Posted on 2023-12-26
442 Oncogenic PIK3CA corrupts growth factor signaling specificity
Madsen, R. R.; Le Marois, A.; Mruk, O.; Voliotis, M.; Yin, S.; Sufi, J.; Qin, X.; Zhao, S. J.; Gorczynska, J.; Morelli, D.; Davidson, L.; Sahai, E.; Korolchuk, V. I.; Tape, C. J.; Vanhaesebroeck, B.
10.1101/2023.12.23.573207 — systems biology — Posted on 2023-12-26
444 Fluvoxamine maleate ameliorates Alzheimer disease pathology by mitigating amyloid-beta load and neuroinflammation in 5XFAD mice
Kaur, S.; Sharma, K.; Sharma, A.; Sandha, K. K.; Ali, S. M.; Ahmed, R.; Ramajayan, P.; Singh, P. P.; Ahmed, Z.; Kumar, A.
10.1101/2023.12.17.572086 — neuroscience — Posted on 2023-12-26
447 Sustained 3D isotropic imaging of subcellular dynamics using adaptive VCD light-field microscopy 2.0
Zhu, L.; Sun, J.; Yi, C.; Zhang, M.; Niu, G.; Tang, J.; Zhang, Y.; Li, D.; Fei, P.; Chen, L.; He, M.; Zhang, Y.; Huang, Y.; Zheng, C.; Wang, J.
10.1101/2023.03.15.532876 — microbiology — Posted on 2023-12-26
450 Federated Learning for multi-omics: a performance evaluation in Parkinson's disease
Danek, B. P.; Makarious, M. B.; Dadu, A.; Vitale, D.; Nalls, M. A.; Sun, J.; Faghri, F.; Lee, P. S.
10.1101/2023.10.04.560604 — bioinformatics — Posted on 2023-12-26
454 Neural network emulation of the human ventricular cardiomyocyte action potential: a tool for more efficient computation in pharmacological studies
Grandits, T.; Augustin, C. M.; Haase, G.; Jost, N.; Mirams, G. R.; Niederer, S. A.; Plank, G.; Varro, A.; Virag, L.; Jung, A.
10.1101/2023.08.16.553497 — cell biology — Posted on 2023-12-25
455 Conserved basal lamina proteins, laminin and nidogen, are repurposed to organize mechanosensory complexes responsible for touch sensation.
Das, A.; Franco, J. A.; Mulcahy, B.; Wang, L.; Chapman, D.; Jaisinghani, C.; Pruitt, B. L.; Zhen, M.; Goodman, M. B.
10.1101/2022.02.11.479800 — cell biology — Posted on 2023-12-26
458 Cytotoxic chemotherapy potentiates the immune response and efficacy of combination CXCR4/PD-1 inhibition in models of pancreatic ductal adenocarcinoma
Raufi, A. G.; Pellicciotta, I.; Palermo, C.; Sastra, S.; Chen, A.; Alouani, E.; Maurer, C.; May, M.; Iuga, A.; Rabadan, R.; Olive, K. P.; Manji, G. A.
10.1101/2023.12.24.573257 — cancer biology — Posted on 2023-12-25
459 Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks
Nguyen, T. H.; Doan, N. N. T.; Tran, T. H.; Huynh, L. A. K.; Doan, P. L.; Nguyen, T. H. H.; Nguyen, V. T. C.; Nguyen, G. T. H.; Nguyen, H.-N.; Giang, H.; Tran, L. S.; Phan, M. D.
10.1101/2023.12.24.573277 — cancer biology — Posted on 2023-12-25
460 Spatial dissection of cellular heterogeneity and functional crosstalk in the tumor microenvironments of gastric cancers
Kim, T.; Lee, S. H.; Lee, D.; Choi, J.; Oh, H. J.; Ham, I.-H.; Ryu, D.; Lee, S.-Y.; Han, D.-J.; Kim, S.; Lee, S.; Hur, H.
10.1101/2023.12.24.573275 — cancer biology — Posted on 2023-12-25
461 Genetic Mapping of Monocyte Fate Decisions Following Myocardial Infarction
Koenig, A. L.; Kadyrov, F. F.; Amrute, J. M.; Yang, S.; Weinheimer, C. J.; Nigro, J. M.; Kovacs, A.; Smith, G.; Lavine, K. J.
10.1101/2023.12.24.573263 — immunology — Posted on 2023-12-25
462 Immuno-Responsive Gene-1: A mitochondrial gene regulates pathogenic Th17 in CNS autoimmunity mouse model
Nematullah, M.; Fatma, M.; Rashid, F.; Ayasolla, K.; Ahmed, M. E.; Sajad, M.; Zahoor, I.; Rattan, R.; Giri, s.
10.1101/2023.12.24.573264 — immunology — Posted on 2023-12-25
464 Classification of iPSC-Derived Cultures Using Convolutional Neural Networks to Identify Single Differentiated Neurons for Isolation or Measurement
Patel, P.; Mohammed Ali, L. K.; Kaushik, U.; Wright, M. G.; Green, K. P.; Waligorski, J. E.; Kremitzki, C. L.; Bachman, G. W.; Elia, S. N.; Buchser, W. J.
10.1101/2023.12.24.573194 — neuroscience — Posted on 2023-12-25
465 A neurotransmitter atlas of the nervous system of C.elegans males and hermaphrodites
Wang, C.; Vidal, B.; Sural, S.; Merritt, D. M.; Toker, I. A.; Vogt, M. C.; Cros, C. C.; Hobert, O.
10.1101/2023.12.24.573258 — neuroscience — Posted on 2023-12-25
467 Transcriptional analysis of neuronal ensembles of alcohol memories within the nucleus accumbens
Aronovici, C.; Prilutski, Y.; Urshansky, N.; Nathanzon, L.; Rubio, F. J.; Savell, K. E.; Hope, B. T.; Barak, S.
10.1101/2023.12.25.573292 — neuroscience — Posted on 2023-12-25
468 Neural circuits underlying context-dependent competition between defensive actions in Drosophila larva
Lehman, M.; Barre, C.; Hasan, M. A.; Flament, B.; Autran, S.; Dhiman, N.; Soba, P.; Masson, J.-B.; Jovanic, T.
10.1101/2023.12.24.573276 — neuroscience — Posted on 2023-12-25
469 Magnetoelectric Nanodiscs Enable Wireless Transgene-Free Neuromodulation
Kim, Y. J.; Driscoll, N.; Kent, N.; Vargas Paniagua, E.; Tabet, A.; Koehler, F.; Manthey, M.; Sahasrabudhe, A.; Signorelli, L.; Gregurec, D.; Anikeeva, P.
10.1101/2023.12.24.573272 — bioengineering — Posted on 2023-12-25
470 Systematic screens for fertility genes essential for malaria parasite transmission reveal conserved aspects of sex in a divergent eukaryote
Sayers, C.; Pandey, V.; Balakrishnana, A.; Michie, K.; Svedberg, D.; Hunziker, M.; Pardo, M.; Choudhary, J. S.; Berntsson, R. P.-A.; Billker, O.
10.1101/2023.12.25.572958 — developmental biology — Posted on 2023-12-25
472 Embryo-restricted responses to maternal IL-17A promote neurodevelopmental disorders in mouse offspring
Andruszewski, D.; Schelmbauer, C.; Uhlfelder, D. C.; Blanfeld, M.; Scherer, L.; Radyushkin, K.; Waisman, A.; Mufazalov, I. A.
10.1101/2023.12.25.573296 — neuroscience — Posted on 2023-12-25
474 Metabolic cost for isometric force scales nonlinearlyand predicts how humans distribute forces across limbs
Sekaripuram Muralidhar, S.; Marin, N.; Melick, C.; Alwan, A.; Wang, Z.; Baldwin, R.; Walcott, S.; Srinivasan, M.
10.1101/2023.12.24.573267 — biophysics — Posted on 2023-12-25
475 How the immune mousetrap works: structural evidence for the immunomodulatory action of a peptide from influenza NS1 protein
Zabrodskaya, Y.; Tsvetkov, V. B.; Shurygina, A.-P.; Vasyliev, K.; Shaldzhyan, A.; Gorshkov, A. N.; Kuklin, A.; Fedorova, N.; Egorov, V. V.
10.1101/2023.12.25.573289 — biophysics — Posted on 2023-12-25
482 Virus-like DNA tracers for characterizing wastewater-based pathogen monitoring systems
Gopal, A.; Machtinger, A. N.; Wang, B.; Rice, D. P.; McLaren, M. R.; Esvelt, K. M.
10.1101/2023.12.24.573197 — synthetic biology — Posted on 2023-12-25
483 Mapping adipocyte interactome networks by HaloTag enrichment mass-spectrometry
Yazaki, J.; Yamanashi, T.; Nemoto, S.; Kobayashi, A.; Han, Y.; Hasegawa, T.; Iwase, A.; Ishikawa, M.; Konno, R.; Imami, K.; Kawashima, Y.; Seita, J.
10.1101/2023.12.24.573280 — biochemistry — Posted on 2023-12-25
485 Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts
Wei, J.; Resztak, J. A.; Alazizi, A.; Mair-Meijers, H. E.; Slatcher, R. B.; Zilioli, S.; Wen, X.; Luca, F.; Pique-Regi, R.
10.1101/2023.12.24.573260 — genomics — Posted on 2023-12-25
489 Gene expression response to temperature acclimation in a model photoheterotrophic marine flavobacterium (Dokdonia sp. MED134)
Robaina-Estevez, S.; Gonzalez, J. M.; Cabello, A. M.; Palacio, A. S.; Gallagher, R.; Lopez-Urrutia, A.; Alonso-Saez, L.
10.1101/2023.12.25.573297 — microbiology — Posted on 2023-12-25
491 Robust trigger wave speed in Xenopus cytoplasmic extracts
Huang, J.-H.; Chen, Y.; Huang, W. Y. C.; Tabatabaee, S.; Ferrell, J. E.
10.1101/2023.12.22.573127 — biophysics — Posted on 2023-12-25
492 Semantic redundancy-aware implicit neural compression for multidimensional biomedical image data
Ma, Y.; Yi, C.; Zhou, Y.; Wang, Z.; Zhao, Y.; Zhu, L.; Wang, J.; Gao, S.; Liu, J.; Yuan, X.; Wang, Z.; Liu, B.; Fei, P.
10.1101/2023.08.22.554284 — bioengineering — Posted on 2023-12-25
493 Annelid methylomes reveal ancestral developmental and ageing-associated epigenetic erosion across Bilateria
Guynes, K.; Sarre, L. A.; Carrillo-Baltodano, A. M.; Davies, B. E.; Xu, L.; Liang, Y.; Martin-Zamora, F. M.; Hurd, P. J.; de Mendoza, A.; Martin-Duran, J. M.
10.1101/2023.12.21.572802 — genomics — Posted on 2023-12-25
494 Atypical Cell Cycle Regulation over Neural Stem Cell Expansion
Qemo, I.; Lubanska, D.; Stringer, K. F.; Fifield, B.-A.; Elabed, Y.; Mahendran, H. P.; Alrashed, S.; Boujeke, E.; Rodzinka, A.; Sorge, A.; Kandalam, S.; Brown, J.; Ghafoor, H.; Arshad, M.; Porter, L.
10.1101/2023.12.22.572899 — molecular biology — Posted on 2023-12-25
497 Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms
Alfatah, M.; Lim, J. J. J.; Zhang, Y.; Naaz, A.; Trishia, C. Y. N.; Yogasundaram, S.; Faidzinn, N. A.; Jovian, J. L.; Eisenhaber, B.; Eisenhaber, F.
10.1101/2023.07.04.547743 — genetics — Posted on 2023-12-25
498 Inferring cell trajectories of spatial transcriptomics via optimal transport analysis
Shen, X.; Huang, K.; Zuo, L.; Ye, Z.; Li, Z.; Yu, Q.; Zou, X.; Wei, X.; Xu, P.; Jin, X.; Xu, X.; Wu, L.; Zhu, H.; Qin, P.
10.1101/2023.09.04.556175 — bioinformatics — Posted on 2023-12-24
501 Dysfunctional Hippocampal-Prefrontal Network Underlies a Multidimensional Neuropsychiatric Phenotype following Early-Life Seizure
Ruggiero, R. N.; Marques, D. B.; Rossignoli, M. T.; De Ross, J. B.; Prizon, T.; Beraldo, I. J. S.; Bueno-Junior, L. S.; Kandratavicius, L.; Peixoto-Santos, J. E.; Aguiar, C. L.; Leite, J. P.
10.1101/2022.12.21.521438 — neuroscience — Posted on 2023-12-24
502 How to control unpredictable others in court-net sports
Yamamoto, Y.; Yokoyama, K.; Kijima, A.; Okumura, M.; Shima, H.; Gohara, K.
10.1101/2023.12.20.572699 — biophysics — Posted on 2023-12-24
503 Gut microbiota influences foraging onset without affecting division of labor and associated physiological hallmarks in honeybees
Liberti, J.; Frank, E. T.; Kay, T.; Kesner, L.; Monie-Ibanes, M.; Quinn, A.; Schmitt, T.; Keller, L.; Engel, P.
10.1101/2023.12.20.570781 — evolutionary biology — Posted on 2023-12-24
506 Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability
Abbott, K. L.; Ali, A.; Reinfeld, B. I.; Deik, A. A. I.; Subudhi, S.; Landis, M. D.; Hongo, R. A.; Young, K. L.; Kunchok, T.; Nabel, C. S.; Crowder, K. D.; Kent, J. R.; Madariaga, M. L. L.; Jain, R. K.; Beckermann, K. E.; Lewis, C. A.; Clish, C. B.; Muir, A.; Rathmell, W. K.; Rathmell, J. C.; Vander Heiden, M. G.
10.1101/2023.12.24.573250 — cancer biology — Posted on 2023-12-24
507 Effect of habitat degradation on hantavirus infection among introduced and endemic small mammals of Madagascar
Dubrulle, J. A.; Kauffman, K.; Soarimalala, V.; Randriamoria, T.; Goodman, S. M.; Herrera, J.; Nunn, C. L.; Tortosa, P.
10.1101/2023.12.24.573235 — zoology — Posted on 2023-12-24
510 Hiding in Plain Sight: Thymic CD8+FOXP3+Tregs sequester CD25 and are enriched in human tissues
Jarvis, L. B.; Howlett, S. K.; Coppard, V. B.; Rainbow, D. B.; Alkwai, S. B.; Ellis, L. B.; Georgieva, Z. B.; Suchanek, O. B.; Mousa, H. S.; Mahbubani, K. T.; Saeb-Parsy, K. B.; Wicker, L. S.; Jones, J. L.
10.1101/2023.12.24.573232 — immunology — Posted on 2023-12-24
516 Structure-function relationships of mucociliary clearance in the human airways
Roth, D.; Sahin, A. T.; Ling, F.; Senger, C.; Quiroz, E.; Calvert, B.; van der Does, A.; Güney, T. G.; Tepho, N.; Glasl, S.; van Schadewijk, A.; von Schledorn, L.; Olmer, R.; Kanso, E.; Nawroth, J. C.; Ryan, A. L.
10.1101/2023.12.24.572054 — biophysics — Posted on 2023-12-24
517 ProHap enables proteomic database generation accounting for population diversity
Vasicek, J.; Kuznetsova, K. G.; Skiadopoulou, D.; Johansson, S.; Njolstad, P. R.; Bruckner, S.; Kall, L.; Vaudel, M.
10.1101/2023.12.24.572591 — bioinformatics — Posted on 2023-12-24
518 Structure and dynamics of secondary and mature rainforests: insights from South Asian long-term monitoring plots
Murali, A.; Kasinathan, S.; Bhat, K.; Ratnam, J.; Sankaran, M.; Mudappa, D.; Raman, T. R. S.; Osuri, A. M.
10.1101/2023.12.24.573243 — ecology — Posted on 2023-12-24
519 2-photon laser printing to mechanically stimulate multicellular systems in 3D
Colombo, F.; Taale, M.; Taheri, F.; Villiou, M.; Debatin, T.; Dulatahu, G.; Kollenz, P.; Schmidt, M.; Schlagheck, C.; Wittbrodt, J.; Selhuber-Unkel, C.
10.1101/2023.12.23.573049 — biophysics — Posted on 2023-12-24
520 The everting Drosophila wing disc is a shape-programmed material
Fuhrmann, J. F.; Krishna, A.; Paijmans, J.; Duclut, C. A.; Eaton, S.; Popovic, M.; Julicher, F.; Modes, C. D.; Dye, N. A.
10.1101/2023.12.23.573034 — biophysics — Posted on 2023-12-24
523 DNA actively contributes to gene expression of paired transcription factors.
Maritato, R.; Medugno, A.; D'Andretta, E.; De Riso, G.; Lupo, M.; Botta, S.; Marrocco, E.; Renda, M.; Sofia, M.; Bacci, M. L.; Surace, E. M.
10.1101/2023.12.22.573078 — genetics — Posted on 2023-12-24
525 Brood care in shell-dwelling cichlids is timed by independent maternal and larval clocks
Parker, A. V.; Stemmer, M.; Graetsch, S.; Dorigo, A.; Rodriguez Ramirez, O.; Adel, A.; Jordan, A. L.; Baier, H.
10.1101/2023.12.22.573114 — evolutionary biology — Posted on 2023-12-24
527 Noninvasive laser irradiation of the cochlea can create auditory perception
Tamai, Y.; Uenaka, M.; Okamoto, A.; Hosokawa, K.; Ito, Y.; Toda, K.; Hiryu, S.; Kobayasi, K. I.
10.1101/2023.05.13.540641 — neuroscience — Posted on 2023-12-24
528 Scaling of ventral hippocampal activity during anxiety
Cerquetella, C.; Gontier, C.; Forro, T.; Pfister, J.-P.; Ciocchi, S.
10.1101/2023.12.22.573072 — neuroscience — Posted on 2023-12-24
533 Predicting the Structural Impact of Human Alternative Splicing
Song, Y.; ZHANG, C.; Omenn, G. S.; O'Meara, M. J.; Welch, J. D.
10.1101/2023.12.21.572928 — bioinformatics — Posted on 2023-12-24
534 Fully flexible molecular alignment enables accurate ligand structure modelling
Wang, Z.; Zhou, F.; Wang, Z.; Li, Y.-Q.; Wang, S.; Zheng, L.; Li, W.; Peng, X.
10.1101/2023.12.17.572051 — bioinformatics — Posted on 2023-12-24
535 Membrane protein sequence features direct post-translational insertion
Kalinin, I. A.; Peled-Zehavi, H.; Barshap, A. B. D.; Tamari, S. A.; Weiss, Y.; Nevo, R.; Fluman, N.
10.1101/2023.12.12.571264 — biochemistry — Posted on 2023-12-24
537 A one-track model for spatiotemporal coordination of Bacillus subtilis septal cell wall synthesis
Whitley, K. D.; Grimshaw, J.; Roberts, D. M.; Karinou, E.; Stansfeld, P. J.; Holden, S.
10.1101/2023.06.29.547024 — microbiology — Posted on 2023-12-24
538 Metabolomics of Mouse Embryonic CSF Following Maternal Immune Activation
Petrova, B.; Lacey, T. E.; Culhane, A. J.; Cui, J.; Raskin, A.; Misra, A.; Lehtinen, M. K.; Kanarek, N.
10.1101/2023.12.06.570507 — neuroscience — Posted on 2023-12-24
540 Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha
Yelina, N. E.; Frangedakis, E.; Wang, Z.; Schreier, T. B.; Rever, J.; Tomaselli, M.; Forestier, E.; Billakurthi, K.; Ren, S.; Bai, Y.; Stewart-Wood, J.; Haseloff, J.; Zhong, S.; Hibberd, J. M.
10.1101/2023.01.23.525199 — plant biology — Posted on 2023-12-24
544 A thalamic hub of action cues coordinates early visual processing and perception
Vega-Zuniga, T.; Sumser, A.; Symonova, O.; Koppensteiner, P.; Schmidt, F. H.; Joesch, M.
10.1101/2023.12.23.573221 — neuroscience — Posted on 2023-12-24
546 Senescent cells inhibit muscle differentiation via the lipid- SASP 15d-PGJ2 mediated modification and control of HRas
Pundlik, S. S.; Sahoo, S. S.; Barik, A.; Venkatesvaran, A.; Jaysingh, M. A.; Math, R. G. H.; Ramanathan, A.
10.1101/2023.12.23.573200 — biochemistry — Posted on 2023-12-24
547 PROTON TRANSFER FROM LIGANDS ACTIVATES EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING
Medina-Gali, R. M.; Martinez-Pinna, J.; Marroqui, L.; Ciordia, S.; Soriano, S.; Mallavia, R.; Grimaldi, M.; Balaguer, P.; Nadal, A.
10.1101/2023.12.23.573228 — biochemistry — Posted on 2023-12-24
549 Combinatory differentiation of human induced pluripotent stem cells generates thymic epithelium that supports thymic crosstalk and directs dendritic- and CD4/CD8 T-cell full development
Provin, N.; d'Arco, M.; Kervagoret, E.; Bruneau, A.; Brusselle, L.; Fourgeux, C.; Poschmann, J.; Saulquin, X.; Guillonneau, C.; David, L.; Giraud, M.
10.1101/2023.12.23.572664 — immunology — Posted on 2023-12-24
551 In vivo validation of late-onset Alzheimer's disease genetic risk factors
Sasner, M.; Preuss, C.; Pandey, R. S.; Uyar, A.; Garceau, D.; Kotredes, K. P.; Williams, H.; Oblak, A.; Lin, P. B.-C.; Perkins, B.; Soni, D. M.; Ingraham, C.; Gosselin, A. L.; Lamb, B. T.; Howell, G.; Carter, G. W.
10.1101/2023.12.21.572849 — neuroscience — Posted on 2023-12-24
553 hopsy - a methods marketplace for convex polytope sampling in Python
Paul, R. D.; Jadebeck, J. F.; Stratmann, A.; Wiechert, W.; Nöh, K.
10.1101/2023.12.22.573091 — systems biology — Posted on 2023-12-24
554 Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo
Coughlin, G. M.; Borsos, M.; Appling, N.; Barcelona, B. H.; Mayfield, A. M. H.; Mackey, E. D.; Eser, R. A.; Chen, X.; Kumar, S. R.; Gradinaru, V.
10.1101/2023.12.23.573214 — bioengineering — Posted on 2023-12-24
555 Internal representation of future interactions in rats
Dvorakova, T.; Lobellova, V.; Manubens-Coda, P.; Sanchez-Jimenez, A.; Villacorta-Atienza, J. A.; Stuchlik, A.; Levcik, D.
10.1101/2023.12.22.573019 — animal behavior and cognition — Posted on 2023-12-23
557 Nutritional characterisation and seasonal variation of goat forages in Central Malawi
Cooke, A. S.; Mvula, W.; Ventura-Cordero, J.; Gwiriri, L. C.; Takahashi, T.; Morgan, E. R.; Lee, M. R. F.; Safalaoh, A.
10.1101/2023.12.22.573017 — zoology — Posted on 2023-12-23
559 A comparative analysis of planarian genomes reveals regulatory conservation in the face of rapid structural divergence
Ivankovic, M.; Brand, J. N.; Pandolfini, L.; Brown, T.; Pippel, M.; Rozanski, A.; Schubert, T.; Grohme, M. A.; Winkler, S.; Robledillo, L.; Zhang, M.; Codino, A.; Gustincich, S.; Vila-Farre, M.; Zhang, S.; Papantonis, A.; Marques, A.; Rink, J. C.
10.1101/2023.12.22.572568 — genomics — Posted on 2023-12-23
560 Machine learning reveals the diversity of human 3D chromatin contact patterns
Gilbertson, E. N.; Brand, C. M.; McArthur, E.; Rinker, D. C.; Kuang, S.; Pollard, K. S.; Capra, J. A.
10.1101/2023.12.22.573104 — genomics — Posted on 2023-12-23
562 Oncogenic PIK3CA corrupts growth factor signaling specificity
Madsen, R. R.; Le Marois, A.; Voliotis, M.; Yin, S.; Sufi, J.; Qin, X.; Zhao, S. J.; Gorczynska, J.; Morelli, D.; Davidson, L.; Sahai, E.; Korolchuk, V. I.; Tape, C. J.; Vanhaesebroeck, B.
10.1101/2023.12.23.573207 — systems biology — Posted on 2023-12-23
563 Integrative genomics reveals the polygenic basis of seedlessness in grapevine
Wang, X.; Liu, Z.; Zhang, F.; Xiao, H.; Cao, S.; Xue, H.; Liu, W.; Su, Y.; Liu, Z.; Zhong, H.; Zhang, F.; Ahmad, B.; Long, Q.; Zhang, Y.; Liu, Y.; Gan, Y.; Hou, T.; Jin, Z.; Wu, X.; Wang, Y.; Peng, Y.; Zhou, Y.
10.1101/2023.12.22.573032 — genetics — Posted on 2023-12-23
564 Phase coding in phoneme processing slows with age
Dapper, K.; Schirmer, J.; Ruettiger, L.; Gaudrain, E.; Baskent, D.; Verhulst, S.; Braun, C.; Dalhoff, E.; Wolpert, S. M.; Knipper, M.; Munk, M. H. J.
10.1101/2023.12.22.573009 — systems biology — Posted on 2023-12-23
565 Linked OXTR Variants Are Associated with Social Behavior Differences in Bonobos (Pan paniscus)
Skiba, S.; Hansen, A.; McCall, R.; Byers, A.; Waldron, S.; Epping, A. J.; Taglialatela, J. P.; Hudson, M. L.
10.1101/2023.12.22.573122 — evolutionary biology — Posted on 2023-12-23
567 Trans-synaptic molecular context of NMDA receptor nanodomains
Anderson, M. C.; Levy, A. D.; Dharmasri, P. A.; Metzbower, S. R.; Blanpied, T. A.
10.1101/2023.12.22.573055 — neuroscience — Posted on 2023-12-23
568 The Brain Image Library: A Community-Contributed Microscopy Resource for Neuroscientists
Kenney, M.; Vasylieva, I.; Hood, G.; Cao-Berg, I.; Tuite, L.; Laghaei, R.; Watson, A. M.; Ropelewski, A. J.
10.1101/2023.12.22.573024 — neuroscience — Posted on 2023-12-23
569 Autism genes converge on microtubule biology and RNA-binding proteins during excitatory neurogenesis
Sun, N.; Teyssier, N.; Wang, B.; Drake, S.; Seyler, M.; Zaltsman, Y.; Everitt, A.; Teerikorpi, N.; Willsey, H. R.; Goodarzi, H.; Tian, R.; Kampmann, M.; Willsey, J.
10.1101/2023.12.22.573108 — systems biology — Posted on 2023-12-23
574 Single-nucleus RNA-sequencing reveals novel potential mechanisms of ovarian insufficiency in 45,X Turner Syndrome
McGlacken-Byrne, S. M.; Del Valle, I.; Xenakis, T.; Suntharalingham, J. P.; Nel, L.; Liptrot, D.; Crespo, B.; Ogunbiyi, O. K.; Niola, P.; Brooks, T.; Solanky, N.; Conway, G. S.; Achermann, J. C.
10.1101/2023.12.22.572342 — genomics — Posted on 2023-12-23
575 Antibody-mediated depletion of select T cell subsets in blood and tissue of nonhuman primates
Sutton, M. S.; Bucsan, A. N.; Lehman, C. C.; Kamath, M.; Pokkali, S.; Magnani, D. M.; Seder, R.; Darrah, P. A.; Roederer, M.
10.1101/2023.12.22.572898 — immunology — Posted on 2023-12-23
578 Neural adaptation at stimulus onset and speed of neural processing as critical contributors to speech comprehension independent of hearing threshold or age
Schirmer, J.; Wolpert, S.; Dapper, K.; Ruehle, M.; Wertz, J.; Wouters, M.; Eldh, T.; Bader, K.; Singer, W.; Gaudrain, E.; Baskent, D.; Verhulst, S.; Braun, C.; Ruettiger, L.; Munk, M. H. J.; Dalhoff, E.; Knipper, M.
10.1101/2023.12.22.573060 — neuroscience — Posted on 2023-12-23
579 Evidence of the ability of endocrine disrupting compounds to induce testicular germ cell cancer in humans.
Nicolas, N.; Moison, D.; Jampy, A.; Dechamps, N.; Messiaen, S.; Abdallah, S.; benachi, a.; pozzi-gaudin, s.; Rouiller-Fabre, V.; Livera, G.; Guerquin, M.-J.
10.1101/2023.12.22.573063 — cancer biology — Posted on 2023-12-23
580 Comprehensive analysis of the functional impact of single nucleotide variants of human CHEK2
McCarthy-Leo, C. E.; Brush, G. S.; Pique-Regi, R.; Luca, F.; Tainsky, M. A.; Finley, R. L.
10.1101/2023.12.22.573093 — cancer biology — Posted on 2023-12-23
581 Error-corrected deep targeted sequencing of circulating cell-free DNA from colorectal cancer patients for sensitive detection of circulating tumor DNA
Frydendahl, A.; Rasmussen, M. H.; Jensen, S. O.; Henriksen, T. V.; Demuth, C.; Diekema, M.; Dietzel, H. J.; Wen, S. W. C.; Pedersen, J. S.; Dyrskjoet, L.; Andersen, C. L.
10.1101/2023.12.22.573042 — cancer biology — Posted on 2023-12-23
582 Piezo1-induced durotaxis of pancreatic stellate cells depends on TRPC1 and TRPV4 channels
Budde, I.; Schlichting, A.; Ing, D.; Schimmelpfennig, S.; Romac, J. M.-J.; Swain, S. M.; Liddle, R. A.; Stevens, A.; Schwab, A.; Petho, Z.
10.1101/2023.12.22.572956 — physiology — Posted on 2023-12-23
583 Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth
Dick, A.; Reginato, M. J.; Beld, J.; Simone, N. L.; Cocklin, S.; Rashad, A. A.; Talarico, A. N.; Merzy, J.; Young, R. G.; Ciraku, L.; Esquea, E.
10.1101/2023.12.22.573073 — cancer biology — Posted on 2023-12-23
584 Exogenous mitochondrial transfer increases energy expenditure and attenuates adiposity gains in mice with diet-induced obesity
Namwanje, M.; Mazumdar, S.; Stayton, A.; Patel, P. S.; Watkins, C.; White, C.; Brown, C.; Eason, J. D.; Mozhui, K.; Kuscu, C.; Pabla, N.; Stephenson, E. J.; Bajwa, A.
10.1101/2023.12.23.573206 — physiology — Posted on 2023-12-23
587 DNA Nanostar Structures with Tunable Auxetic Properties
Du, Y.; Li, R.; Madhvacharyula, A. S.; Swett, A. A.; Choi, J. H.
10.1101/2023.12.22.573109 — biophysics — Posted on 2023-12-23
590 Single-molecule FRET and molecular dynamics simulations reveal early activation steps of MET receptor by Listeria monocytogenes
Li, Y.; Arghittu, S. M.; Dietz, M. S.; Hasse, D.; Ferraris, D. M.; Freund, P.; Barth, H.-D.; Niemann, H. H.; Covino, R.; Heilemann, M.
10.1101/2023.12.22.572978 — biophysics — Posted on 2023-12-23
592 EryDB: a transcriptomic profile database for erythropoiesis and erythroid-related diseases
Zheng, G.; Wu, S.; Zhang, Z.; Xin, Z.; Zhang, L.; Zhao, S.; Wu, J.; Liu, Y.; Li, M.; Ruan, X.; Bao, Y.; Qu, H.; Fang, X.
10.1101/2023.12.22.572961 — bioinformatics — Posted on 2023-12-23
600 Modeling cellular self-organization in strain-stiffening hydrogels
Erhardt, A. H.; Peschka, D.; Dazzi, C.; Schmeller, L.; Petersen, A.; Checa, S.; Muench, A.; Wagner, B.
10.1101/2023.12.21.572812 — bioengineering — Posted on 2023-12-23
601 Harnessing Bilayer Biomaterial Delivery of FTY720 as an Immunotherapy to Accelerate Oral Wound Healing
Toma, A. I.; Shah, D.; Roth, D.; Oliver Pina, J.; Hymel, L. A.; Turner, T.; Kamalakar, A.; Liu, K.; Bartsch, P. W.; Jacobs, L.; D'Souza, R.; Liotta, D.; Botchwey, E.; Willett, N. J.; Goudy, S. L.
10.1101/2023.12.22.573096 — bioengineering — Posted on 2023-12-23
603 Conditions for successful nitrogen removal from source-separated urine by partial nitritation/anammox
Faust, V.; Markus, P.; Schielke-Jenni, S.; Timmer, M.; De Paepee, J.; Ganigue, R.; Vlaeminck, S.; Udert, K.
10.1101/2023.12.22.573048 — bioengineering — Posted on 2023-12-23
604 Dual carbon sequestration with photosynthetic living materials
Dranseike, D.; Cui, Y.; Ling, A. S.; Donat, F.; Bernhard, S.; Bernero, M.; Areeckal, A.; Qin, X.-H.; Oakey, J. S.; Dillenburger, B.; Studart, A. R.; Tibbitt, M. W.
10.1101/2023.12.22.572991 — bioengineering — Posted on 2023-12-23
605 Automated In Vitro Wound Healing Assay
Cwycyshyn, J.; Stansbury, C.; Meixner, W.; Hoying, J. B.; Muir, L. A.; Rajapakse, I.
10.1101/2023.12.23.573213 — bioengineering — Posted on 2023-12-23
606 Atomic context-conditioned protein sequence design using LigandMPNN
Dauparas, J.; Lee, G. R.; Pecoraro, R.; An, L.; Anishchenko, I.; Glasscock, C.; Baker, D.
10.1101/2023.12.22.573103 — biochemistry — Posted on 2023-12-23
609 DNA actively contributes to gene expression of paired transcription factors.
Maritato, R.; Medugno, A.; D'Andretta, E.; De Riso, G.; Lupo, M.; Botta, S.; Marrocco, E.; Renda, M.; Sofia, M.; Bacci, M. L.; Surace, E. M.
10.1101/2023.12.22.573078 — genetics — Posted on 2023-12-23
613 Genome assemblies and genetic maps highlight chromosome-scale macrosynteny in Atlantic acroporids
Locatelli, N. S.; Kitchen, S. A.; Stankiewicz, K. H.; Osborne, C. C.; Dellaert, Z.; Elder, H.; Kamel, B.; Koch, H. R.; Fogarty, N. D.; Baums, I. B.
10.1101/2023.12.22.573044 — evolutionary biology — Posted on 2023-12-23
618 Comparison of gastric inflammation and metaplasia induced by Helicobacter pylori or Helicobacter felis colonization in mice
Druffner, S. R.; Venkateshwaraprabu, S.; Khadka, S.; Duncan, B. C.; Morris, M. T.; Sen-Kilic, E.; Damron, F. H.; Liechti, G. W.; Busada, J. T.
10.1101/2023.12.22.573128 — immunology — Posted on 2023-12-23
620 Functional mapping of the somatosensory cortex using noninvasive fMRI and touch in awake dogs
Guran, C.- N. A.; Boch, M.; Sladky, R.; Lonardo, L.; Karl, S.; Huber, L.; Lamm, C.
10.1101/2023.12.22.572785 — neuroscience — Posted on 2023-12-23
622 Single-nucleus multiomic atlas of frontal cortex in amyotrophic lateral sclerosis with a deep learning-based decoding of alternative polyadenylation mechanisms
McKeever, P. M.; Sababi, A. M.; Sharma, R.; Khuu, N.; Xu, Z.; Shen, S. Y.; Xiao, S.; McGoldrick, P.; Orouji, E.; Ketela, T.; Sato, C.; Moreno, D.; Visanji, N.; Kovacs, G. G.; Keith, J.; Zinman, L.; Rogaeva, E.; Goodarzi, H.; Bader, G.; Robertson, J.
10.1101/2023.12.22.573083 — neuroscience — Posted on 2023-12-23
624 Multilayer Network Analysis across Cortical Depths in Resting-State 7T fMRI
Kotlarz, P.; Lankinen, K.; Hakonen, M.; Turpin, T.; Polimeni, J. R.; Ahveninen, J.
10.1101/2023.12.23.573208 — neuroscience — Posted on 2023-12-23
625 Reliability of task-based fMRI in the dorsal horn of the human spinal cord
Dabbagh, A.; Horn, U.; Kaptan, M.; Mildner, T.; Mueller, R.; Lepsien, J.; Weiskopf, N.; Brooks, J. C.; Finsterbusch, J.; Eippert, F.
10.1101/2023.12.22.572825 — neuroscience — Posted on 2023-12-23
627 CompHEAR: A Customizable and Scalable Web-Enabled Auditory Performance Evaluation Platform for Cochlear Implant Sound Processing Research
Tward, A.; Merrill, K.; Muller, L.; Beim, J. A.; Hehrmann, P.; Swan, D.; Alfsmann, D.; Spahr, T.; Litvak, L.; Oxenham, A. J.
10.1101/2023.12.22.573126 — neuroscience — Posted on 2023-12-23
629 Human cerebrospinal fluid single exosomes in Parkinson and Alzheimer diseases
Yakabi, K.; Berson, E.; Montine, K. S.; Bendall, S. C.; MacCoss, M. J.; Poston, K. L.; Montine, T. J.
10.1101/2023.12.22.573124 — neuroscience — Posted on 2023-12-23
632 Angiotensin-II drives changes in microglia-vascular interactions in rats with heart failure
Althammer, F.; Roy, R. K.; Kirchner, M. K.; McGrath, S.; Lira, E. C.; Stern, J. E.
10.1101/2023.12.22.573045 — neuroscience — Posted on 2023-12-23
634 Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decreases ISR activation in DRG neurons
Yousuf, M. S.; Mancilla Moreno, M.; Li, J.; He, L.; Royer, D.; Zhang, J.; Woodall, B. J.; Grace, P. M.; Price, T. J.
10.1101/2023.12.22.572877 — neuroscience — Posted on 2023-12-23
635 Open-ST: High-resolution spatial transcriptomics in 3D
Schott, M.; Leon-Perinan, D.; Splendiani, E.; Strenger, L.; Licha, J. R.; Pentimalli, T. M.; Schallenberg, S.; Alles, J.; Samut Tagliaferro, S.; Boltengagen, A.; Ehrig, S.; Abbiati, S.; Dommerich, S.; Pagani, M.; Ferretti, E.; Macino, G.; Karaiskos, N.; Rajewsky, N.
10.1101/2023.12.22.572554 — systems biology — Posted on 2023-12-23
639 Optimization of neuromuscular blockade protocols in cynomolgus macaques: monitoring, doses and antagonism
Letscher, H.; Lemaitre, J.; Burban, E.; Le Grand, R.; Bruhns, P.; Relouzat, F.; Gouel-Cheron, A.
10.1101/2023.12.22.573006 — pathology — Posted on 2023-12-23
640 A diverse proteome is present and enzymatically active in metabolite extracts
House, R. J.; Soper-Hopper, M. T.; Vincent, M. P.; Ellis, A. E.; Capan, C. D.; Madaj, Z. B.; Wolfrum, E.; Isaguirre, C.; Castello, C. D.; Johnson, A.; Escobar Galvis, M. L.; Williams, K.; Lee, H.; Sheldon, R. D.
10.1101/2023.12.22.573071 — biochemistry — Posted on 2023-12-23
641 Dissecting the Complexities of Learning With Infinite Hidden Markov Models
Bruijns, S. A.; International Brain Laboratory, ; Bougrova, K.; Laranjeira, I. C.; Lau, P. Y. P.; Meijer, G. T.; Miska, N. J.; Noel, J.-P.; Pan-Vazquez, A.; Roth, N.; Socha, K. Z.; Urai, A. E.; Dayan, P.
10.1101/2023.12.22.573001 — animal behavior and cognition — Posted on 2023-12-23
642 Chromosome fusion and programmed DNA elimination shape karyotypes of parasitic nematodes
Simmons, J. R.; Estrem, B.; Zagoskin, M. V.; Oldridge, R.; Zadegan, S. B.; Wang, J.
10.1101/2023.12.21.572835 — genomics — Posted on 2023-12-23
643 Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription
Altintas, U. B.; Seo, J.-H.; Giambartolomei, C.; Ozturan, D.; Fortunato, B.; Nelson, G.; Goldman, S.; Adelman, K.; Hach, F.; Freedman, M. L.; Lack, N. A.
10.1101/2023.12.22.573134 — genomics — Posted on 2023-12-23
644 Sex-Specific DNA-Replication In The Early Mammalian Embryo
Halliwell, J. A.; Martin-Gonzalez, J.; Hashim, A.; Dahl, J. A.; Hoffmann, E. R.; Lerdrup, M.
10.1101/2023.12.22.572993 — genomics — Posted on 2023-12-23
649 Phylogenomics recovers multiple origins of portable case-making in caddisflies (Insecta: Trichoptera), the world's most common underwater architects
Frandsen, P. B.; Holzenthal, R. W.; Espeland, M.; Breinholt, J.; Thomas, J. A.; Simon, S.; Kawahara, A. Y.; Plotkin, D.; Hotaling, S.; Li, Y.; Nelson, C. R.; Niehuis, O.; Mayer, C.; Podsiadlowski, L.; Donath, A.; Misof, B.; Lemmon, E.; Lemmon, A. R.; Morse, J. C.; Pauls, S. U.; Zhou, X.
10.1101/2023.12.21.572910 — evolutionary biology — Posted on 2023-12-23
652 Acclimation Capacity to Global Warming of Amphibians and Freshwater Fishes: Drivers, Patterns, and Data Limitations
Ruthsatz, K.; Dahlke, F.; Alter, K.; Wohlrab, S.; Eterovick, P. C.; Lyra, M. L.; Gippner, S.; Cooke, S. J.; Peck, M. A.
10.1101/2023.12.22.573141 — ecology — Posted on 2023-12-23
653 Biodiversity in mountain soils above the treeline
Praeg, N.; Steinwandter, M.; Urbach, D.; Snethlage, M. A.; Alves, R. P.; Apple, M. E.; Britton, A. J.; Bruni, E. P.; Chen, T.-W.; Dumack, K.; Fernandez-Mendoza, F.; Freppaz, M.; Frey, B.; Fromin, N.; Geisen, S.; Grube, M.; Guariento, E.; Guisan, A.; Ji, Q.-Q.; Jimenez, J. J.; Maier, S.; Malard, L. A.; Minor, M. A.; Mc Lean, C. C.; Mitchell, E. A. D.; Peham, T.; Pizzolotto, R.; Taylor, A. F. S.; Vernon, P.; van Tol, J. J.; Wu, Y.; Wu, D.; Xie, Z.; Weber, B.; Illmer, P.; Seeber, J.
10.1101/2023.12.22.569885 — ecology — Posted on 2023-12-23
654 Connectivity at home: A data-driven connectivity modeling framework for home range movements in heterogeneous landscapes
Merkens, L.; Mimet, A.; Bae, S.; Fairbairn, A.; Muehlbauer, M.; Lauppe, E.; Mesarek, F.; Stauffer-Bescher, D.; Hauck, T. E.; Weisser, W. W.
10.1101/2023.12.22.571399 — ecology — Posted on 2023-12-23
660 Analysis of Metabolomics and Transcriptomics Data to Assess Interactions in Microalgal Co-culture of Skeletonema marinoi and Prymnesium parvum
Zulfiqar, M.; Abel, A.-S.; Barth, E.; Syhapanha, K.; Poulin, R. X.; Dehiwalage, S. N. C. W.; Pohnert, G.; Steinbeck, C.; Peters, K.; Sorokina, M.
10.1101/2023.12.23.573174 — microbiology — Posted on 2023-12-23
661 PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
Martinez Bedoya, D.; Marinari, E.; Davanture, S.; Castillo Cantero, L.; Erraiss, S.; Dockerill, M.; Barluenga Badiola, S.; Winssinger, N.; Schaller, K.; Bijlenga, P.; Momjian, S.; Hammel, P.; Cosson, P.; Walker, P. R.; Dutoit, V.; Migliorini, D.
10.1101/2023.12.23.573190 — immunology — Posted on 2023-12-23
663 News without the buzz: reading out weak theta rhythms in the hippocampus
Agarwal, G.; Lustig, B.; Akera, S.; Pastalkova, E.; Lee, A. K.; Sommer, F. T.
10.1101/2023.12.22.573160 — neuroscience — Posted on 2023-12-23
665 Nitric oxide mediates differential effects in mouse retinal ganglion cells
Gonschorek, D.; Goldin, M. A.; Oesterle, J.; Schwerd-Kleine, T.; Arlinghaus, R.; Zhao, Z.; Schubert, T.; Marre, O.; Euler, T.
10.1101/2023.12.23.572742 — neuroscience — Posted on 2023-12-23
669 The Treatment of diarrheal mice with Tenebrio Molitor meal
Liu, t. t.; wang, Q. l.; wang, z. l.; yan, j. x.; zhu, j. j.; shen, h.; wang, j. g.
10.1101/2023.12.21.572900 — zoology — Posted on 2023-12-23
673 Gene expression signatures of salinity transitions in Limia perugiae (Poeciliidae), with comparisons to other teleosts
Wilson, E. J.; Barts, N.; Coffin, J.; Johnson, J. B.; Rodriguez Pena, C. M.; Kelley, J. L.; Tobler, M.; Greenway, R.
10.1101/2023.12.21.572917 — physiology — Posted on 2023-12-23
674 Sweet and fatty symbionts: photosynthetic productivity and carbon storage boosted in microalgae within a host
Catacora Grundy, A.; Chevalier, F.; Yee, D.; LeKieffre, C.; Schieber, N.; Schwab, Y.; Gallet, B.; Jouneau, P.-H.; Curien, G.; Decelle, J.
10.1101/2023.12.22.572971 — physiology — Posted on 2023-12-23
675 An Immunological Synapse Formation Between T Regulatory Cells and Cancer-Associated Fibroblasts Promotes Tumor Development
Varveri, A.; Papadopoulou, M.; Papadovasilakis, Z.; Compeer, E. B.; Legaki, A. I.; Delis, A.; Damaskou, V.; Boon, L.; Papadogiorgaki, S.; Samiotaki, M.; Foukas, P. G.; Hatzioannou, A.; Alissafi, T.; Dustin, M. L.; Verginis, P.
10.1101/2023.12.22.572969 — cancer biology — Posted on 2023-12-23
676 PIEZO1-HaloTag hiPSCs: Bridging Molecular, Cellular and Tissue Imaging
Bertaccini, G. A.; Evans, E. L.; Nourse, J. L.; Dickinson, G. D.; Liu, G.; Casanellas, I.; Seal, S.; Ly, A. T.; Holt, J. R.; Yan, S.; Hui, E. E.; Panicker, M. M.; Upadhyayula, S.; Parker, I.; Pathak, M. M.
10.1101/2023.12.22.573117 — biophysics — Posted on 2023-12-23
677 Detection of pathogenic bacteria in ticks from Isiolo and Kwale counties of Kenya using metagenomics.
Kimemia, B. B.; Musila, L.; Langat, S.; Odoyo, E.; Cinkovich, S.; Abuom, D.; Yalwala, S.; Khamadi, S.; Johnson, J.; Garges, E.; Ojwang, E.; Eyase, F.
10.1101/2023.12.21.572930 — bioinformatics — Posted on 2023-12-23
680 Biodistribution of DNA-origami nanostructures in live zebrafish embryos with single-cell resolution
Kolonelou, C.; Bräutigam, L.; Edwards, S.; Engström, E.; Dias, J. M.; Spratt, J.; Karampelias, C.; Wennmalm, S.; Brismar, H.; Andersson, O.; Teixeira, A. I.
10.1101/2023.12.22.572973 — bioengineering — Posted on 2023-12-23
684 TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts
White, S. E.; Schwartze, T. A.; Mukundan, A.; Schoenherr, C.; Singh, S. P.; van Dinther, M.; Cunningham, K. T.; White, M. P. J.; Campion, T.; Pritchard, J.; Hinck, C. S.; ten Dijke, P.; Inman, G.; Maizels, R. M.; Hinck, A. P.
10.1101/2023.12.22.573140 — biochemistry — Posted on 2023-12-23
686 Stable chromosome configuration and loop-based polarization in animal symbionts
Viehboeck, T.; Weber, P. M.; Krause, N.; Varoquaux, N.; Boccard, F.; Junier, I.; Bulgheresi, S.; Lioy, V. S.
10.1101/2023.12.21.572873 — genomics — Posted on 2023-12-23
689 RNA polymerases reshape chromatin and coordinate transcription on individual fibers
Tullius, T. W.; Isaac, R. S.; Ranchalis, J.; Dubocanin, D.; Churchman, L. S.; Stergachis, A. B.
10.1101/2023.12.22.573133 — genomics — Posted on 2023-12-23
690 The pattern of genetic variability in a core collection of 2,021 cowpea accessions
Fiscus, C. J.; Herniter, I. A.; Tchamba, M.; Paliwal, R.; Munoz-Amatriain, M.; Roberts, P. A.; Abberton, M.; Alaba, O.; Close, T. J.; Oyatomi, O.; Koenig, D.
10.1101/2023.12.21.572659 — genetics — Posted on 2023-12-23
692 Evolution of Multicellularity Genes in the Lead Up to the Great Oxidation Event
Boden, J. S.; Nieves-Morion, M.; Nurnberg, D. J.; Arevalo, S.; Flores, E.; Sanchez-Baracaldo, P.
10.1101/2023.12.23.573081 — evolutionary biology — Posted on 2023-12-23
693 Genome evolution is surprisingly predictable after initial hybridization
Langdon, Q. K.; Groh, J. S.; Aguillon, S.; Powell, D. L.; Gunn, T. R.; Payne, C. Y.; Baczenas, J. J.; Donny, A.; Dodge, T. O.; Du, K.; Schartl, M.; Rios-Cardenas, O.; Gutierrez-Rodriguez, C.; Morris, M.; Schumer, M.
10.1101/2023.12.21.572897 — evolutionary biology — Posted on 2023-12-23
694 Horizontal transfers between fungal Fusarium species contributed to successive outbreaks of coffee wilt disease
Peck, L. D.; Llewellyn, T.; Bennetot, B.; O'Donnell, S.; Nowell, R. W.; Ryan, M. J.; Flood, J.; Rodriguez de la Vega, R. C.; Ropars, J.; Giraud, T.; Spanu, P. D.; Barraclough, T. G.
10.1101/2023.12.22.572981 — evolutionary biology — Posted on 2023-12-23
695 Brood care in shell-dwelling cichlids is timed by independent maternal and larval clocks
Parker, A. V.; Stemmer, M.; Graetsch, S.; Dorigo, A.; Rodriguez Ramirez, O.; Baier, H.; Adel, A.; Jordan, A. L.
10.1101/2023.12.22.573114 — evolutionary biology — Posted on 2023-12-23
703 Learning a conserved mechanism for early neuroectoderm morphogenesis
Lefebvre, M. F.; Colen, J.; Claussen, N. H.; Brauns, F.; Raich, M. K.; Mitchell, N.; Fruchart, M.; Vitelli, V.; Streichan, S. J.
10.1101/2023.12.22.573058 — developmental biology — Posted on 2023-12-23
705 3D genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes
Cordero, J.; Swaminathan, G.; Rogel-Ayala, D. G.; Rubio, K.; Elsherbiny, A.; Guenther, S.; Braun, T.; Dobreva, G.; Barreto, G.
10.1101/2023.12.22.573061 — molecular biology — Posted on 2023-12-23
707 T cell exhaustion dynamics in systemic autoimmune disease
Turner, C. N.; Camilo Sanchez Arcila, J.; Huerta, N.; Quiguoe, A. R.; Jensen, K. D. C.; Hoyer, K. K.
10.1101/2023.12.23.573167 — immunology — Posted on 2023-12-23
708 Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses
Brouwer, P. J. M.; Perrett, H. R.; Beaumont, T.; Nijhuis, H.; Kruijer, S.; Burger, J. A.; Lee, W.-H.; Muller-Krauter, H.; Sanders, R. W.; Strecker, T.; van Gils, M. J.; Ward, A. B.
10.1101/2023.12.21.572918 — immunology — Posted on 2023-12-23
710 Fast inhibition slows and desynchronizes auditory efferent neuron activity
Fischl, M.; Pederson, A.; Voglewede, R.; Cheng, H.; Drew, J.; Torres Cadenas, L.; Weisz, C.
10.1101/2023.12.21.572886 — neuroscience — Posted on 2023-12-23
711 RELEVANCE OF SHAM CONTROL GROUP IN PRECLINICAL ANIMAL STUDIES OF CEREBRAL ISCHEMIA
Candamo-Lourido, M.; Lopez-Arias, E.; Lopez-Amoedo, S.; Correa-Paz, C.; B. Bravo, S.; Bugallo-Casal, A.; del Pozo-Filiu, L.; Perez-Gayol, L.; Palomar-Alonso, N.; Chantada-Vazquez, M. P.; Campos, F.; Perez-Mato, M.
10.1101/2023.12.21.572908 — neuroscience — Posted on 2023-12-23
712 Behavioral relevance of category selectivity revealed by human ECoG data
Hashemi, S.; Ebadi, S. A.; Zareayan Jahrom, F.; Treue, S.; Kreiman, G.; Esghaei, M.
10.1101/2023.12.22.571904 — neuroscience — Posted on 2023-12-23
715 Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles
Oehlenschlaeger, M. S.; Jensen, P.; Havelund, j. F.; Sutcliffe, M.; Elmkvist, S. B.; Criscuolo, L.; Wingett, S. W.; Jakobsen, L. A.; Brewer, J.; Faergeman, N. J.; Lancaster, M. A.; Larsen, M. R.; Bogetofte, H.
10.1101/2023.12.21.572871 — neuroscience — Posted on 2023-12-23
716 Multipair phase-modulated temporal interference electrical stimulation combined with fMRI.
Savvateev, I.; Missey, F.; Beliaeva, V.; Markicevic, M.; Kindler, D.; Razansky, D.; Jirsa, V.; Williamson, A.; Polania, R.; Zerbi, V.
10.1101/2023.12.21.571679 — neuroscience — Posted on 2023-12-23
721 Characterization of peroxidasin expression in histologically normal human adult and fetal kidney tissue
Brandao, I.; Silva, R.; Conde, E.; Gomes, B.; Sampaio, P.; Costa Braga, A.; Reis Almeida, J.; Alencastre, I.; Oliveira, J. P.
10.1101/2023.12.21.572848 — physiology — Posted on 2023-12-23
722 Identification of ligands binding to MB327-PAM-1, a binding pocket relevant for resensitization of nAChRs
Kaiser, J.; Gertzen, C. G. W.; Bernauer, T.; Nitsche, V.; Höfner, G.; Niessen, K. V.; Seeger, T.; Paintner, F. F.; Wanner, K. T.; Steinritz, D.; Worek, F.; Gohlke, H.
10.1101/2023.12.21.572862 — pharmacology and toxicology — Posted on 2023-12-23
723 Deletion of Glyoxalase 1 exacerbates acetaminophen-induced hepatotoxicity in mice
Dobariya, P.; Xie, W.; Rao, S. P.; Xie, J.; Seelig, D. M.; Vince, R.; Lee, M. K.; More, S. S.
10.1101/2023.12.21.572856 — pharmacology and toxicology — Posted on 2023-12-23
726 ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3
Ebegboni, V. J.; Jones, T. L.; Brownmiller, T.; Zhao, P. X.; Pehrsson, E. C.; Sundara Rajan, S.; Caplen, N.
10.1101/2023.12.21.572864 — cancer biology — Posted on 2023-12-23
727 Early Jurassic origin of avian endothermy and thermophysiological diversity in Dinosauria
Chiarenza, A. A.; Cantalapiedra, J. L.; Jones, L. A.; Gamboa, S.; Galvan, S.; Farnsworth, A. J.; Valdes, P.; Sotelo, G.; Varela, S.
10.1101/2023.12.21.572807 — paleontology — Posted on 2023-12-23
728 NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer
Ridnourl, L. A.; Heinz, W. F.; Cheng, R. Y.; Wink, A. L.; Kedei, N.; Pore, M.; Imtiaz, F.; Femino, E. L.; Gonzalez, A. L.; Coutinho, L.; Butcher, D.; Edmondson, E. F.; Rangel, C.; Kinders, R. J.; Lipkowitz, S.; Wong, S. T.; Anderson, S. K.; McVicar, D. W.; Li, X.; Glynn, S.; Billiar, T. R.; Chang, J. C.; Hewitt, S. M.; Ambs, S.; Lockett, S. J.; Wink, D. A.
10.1101/2023.12.21.572859 — cancer biology — Posted on 2023-12-23
729 Colon Cancer Cells Evade Drug Action by Enhancing Drug Metabolism
Cong, B.; Thakur, T.; Uribe, A. H.; Stamou, E.; Gopinath, S.; Maddocks, O.; Cagan, R.
10.1101/2023.12.21.572817 — cancer biology — Posted on 2023-12-23
730 Attenuation of the CpG Island Methylator Phenotype and lack of WNT signaling activation restrains Kras mutant intestinal neoplasia
Fennell, L. J.; Tria, S.; Liu, C.; Kane, A.; McKeone, D.; Borowsky, J.; Chai, L.; Randall-demllo, S.; Bond, C. E.; Leggett, B.; Whitehall, V. L.
10.1101/2023.12.21.572936 — cancer biology — Posted on 2023-12-23
731 Phosphorylation regulates tau's phase separation behavior and interactions with chromatin
Abasi, L. S.; Elathram, N.; Movva, M.; Deep, A.; Corbett, K. D.; Debelouchina, G. T.
10.1101/2023.12.21.572911 — biophysics — Posted on 2023-12-23
732 De novo design of drug-binding proteins with predictable binding energy and specificity
Lu, L.; Gou, X.; Tan, S.; Mann, S.; Yang, H.; Zhong, X.; Gazgalis, D.; Valdiviezo, J.; Jo, H.; Wu, Y.; Diolaiti, M.; Ashworth, A.; Polizzi, N.; DeGrado, W.
10.1101/2023.12.23.573178 — biophysics — Posted on 2023-12-23
733 Oblique Line Scan Illumination Enables Expansive, Accurate and Sensitive Single Protein Measurements in Solution and in Living Cells
Driouchi, A.; Bretan, M.; Davis, B. J.; Heckert, A. B.; Seeger, M.; Bradley Silva, M.; Forrest, W. S.; Hsiung, J.; Tan, J.; Yang, H.; McSwiggen, D. T.; Song, L.; Sule, A.; Abaie, B.; Conroy, B.; Elliott, L. A.; Gonzalez, E.; Ilkov, F.; Isaacs, J.; Labaria, G.; Lagana, M.; Larsen, D. D.; Margolin, B.; Nguyen, M. K.; Rine, J.; Tang, Y.; Vana, M.; Wilkey, A.; Zhang, Z.; Basham, S.; Ho, J. J.; Johnson, S.; Klammer, A. A.; Lin, K.; Darzacq, X.; Betzig, E.; Berman, R. T.; Anderson, D. J.
10.1101/2023.12.21.571765 — biophysics — Posted on 2023-12-23
734 Nanoscale profiling of evolving intermolecular interactions in ageing FUS condensates
Miller, A.; Toprakcioglu, Z.; Qamar, S.; St.George-Hyslop, P.; Ruggeri, F. S.; Knowles, T. P. J.; Vendruscolo, M.
10.1101/2023.12.21.572955 — biophysics — Posted on 2023-12-23
736 A novel framework to build saliva-based DNA methylation biomarkers: quantifying systemic chronic inflammation as a case study
Schmunk, L. J.; Call, T. P.; McCartney, D. L.; Javaid, H.; Hastings, W. J.; Jovicevic, V.; Kojadinovic, D.; Tomkinson, N.; Zlamalova, E.; McGee, K. C.; Sullivan, J.; Campbell, A.; McIntosh, A. M.; Ovari, V.; Wishart, K.; Behrens, C. E.; Stone, E.; Gavrilov, M.; Thompson, R.; Hurdle bio-infrastructure team, ; Jackson, T.; Lord, J. M.; Stubbs, T. M.; Marioni, R. E.; Martin-Herranz, D. E.
10.1101/2023.12.21.572866 — bioinformatics — Posted on 2023-12-23
739 ConBoTNet: supervised contrastive learning enhances MHC-II peptide binding affinity prediction
Shen, L.-C.; Yan, L.; Liu, Z.; Zhang, Y.; Wang, Z.; Guo, Y.; Rossjohn, J.; Song, J.; Yu, D.-J.
10.1101/2023.12.21.572942 — bioinformatics — Posted on 2023-12-23
742 Sopa: a technology-invariant pipeline for analyses of image-based spatial-omics
Blampey, Q.; Mulder, K.; Gardet, M.; Dutertre, C.-A.; Andre, F.; Ginhoux, F.; Cournede, P.-H.
10.1101/2023.12.22.571863 — bioinformatics — Posted on 2023-12-23
744 Development of a robotic cluster for automated and scalable cell therapy manufacturing
Melocchi, A.; Schmittlein, B.; Jones, A. L.; Ainane, Y.; Rizvi, A.; Chan, D.; Dickey, E.; Pool, K.; Harsono, K.; Szymkiewicz, D.; Scarfogliero, U.; Bhatia, V.; Sivanantham, A.; Kreciglowa, N.; Hunter, A.; Gomez, M.; Tanner, A.; Uboldi, M.; Batish, A.; Balcerek, J.; Kutova-Stoilova, M.; Paruthiyil, S.; Acevedo, L. A.; Stadnitskiy, R.; Carmichael, S.; Aulbach, H.; Hewitt, M.; De Mollerat Du Jeu, X.; di Robilant, B.; Parietti, F.; Esensten, J. H.
10.1101/2023.12.21.572854 — bioengineering — Posted on 2023-12-23
745 Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Raimi, O.; Ojha, H.; Ehses, K.; Dederer, V.; Lange, S.; Rivera, C. P.; Deegan, T.; Chen, Y.; Wightman, M.; Toth, R.; Labib, K.; Mathea, S.; Ranson, N.; Fernandez-Busnadiego, R. F.; Muqit, M.
10.1101/2023.12.23.573181 — biochemistry — Posted on 2023-12-23
748 In vitro differentiation of mouse pluripotent stem cells into glucocorticoid-producing adrenocortical cells
Oikonomakos, I.; Tedesco, M.; Jian-Motamedi, F.; Peitzsch, M.; Nef, S.; Bornstein, S.; Schedl, A.; Steenblock, C.; Neirijnck, Y.
10.1101/2023.12.22.572808 — developmental biology — Posted on 2023-12-23
749 ROS-induced translational regulation--through spatiotemporal differences in codon recognition--is a key driver of brown adipogenesis
Ip, J. Y.; Wijaya, I.; Lee, L. T.; Lim, Y.; Teoh, D. E.-J.; Chan, C. S. C.; Cui, L.; Begley, T. J.; Dedon, P. C.; Guo, H.
10.1101/2023.12.22.572954 — molecular biology — Posted on 2023-12-23
750 Novel nitrifying symbiont lineages are vertically inherited and widespread in marine sponges
Glasl, B.; Luter, H. M.; Damjanovic, K.; Kitzinger, K.; Mueller, A. J.; Mahler, L.; Engelberts, J. P.; Rix, L.; Osvatic, J. T.; Hausmann, B.; Seneca, J.; Daims, H.; Pjevac, P.; Wagner, M.
10.1101/2023.12.23.573102 — microbiology — Posted on 2023-12-23
752 Cryo-EM structure of monomeric CXCL12-bound CXCR4 in active state
Liu, Y.; Liu, A.; Li, X.; Liao, Q.; Zhang, W.; Zhu, L.; Ye, R. D.
10.1101/2023.12.21.572776 — immunology — Posted on 2023-12-23
753 The ICF2 gene Zbtb24 specifically regulates the differentiation of B1 cells via promoting heme synthesis
Wang, J.; Gao, H.; Zhao, S.; Dai, X.; Zheng, W.; Zhu, C.; Wang, H.; Zhu, X.; Gong, F.; Gao, X.; Zhao, Y.
10.1101/2023.12.23.573176 — immunology — Posted on 2023-12-23
754 Neutrophil extracellular traps formation is associated with postoperative complications in neonates and infants undergoing congenital cardiac surgery
Maisat, W.; Hou, L.; Sandhu, S.; Sin, Y.-C.; Kim, S.; Van Pelt, H.; Chen, Y.; Emani, S.; Kong, S. w.; Emani, S.; Ibla, J.; Yuki, K.
10.1101/2023.12.21.572768 — immunology — Posted on 2023-12-23
757 Kappa Opioid Receptors in Mesolimbic Terminals Mediate Escalation of Cocaine Consumption
Gordon-Fennell, L.; Farero, R. D.; Burgeno, L. M.; Murray, N. L.; Abraham, A. D.; Soden, M. E.; Stuber, G. D.; Chavkin, C.; Zweifel, L. S.; Phillips, P. E. M.
10.1101/2023.12.21.572842 — neuroscience — Posted on 2023-12-23
759 Presenilin-dependent regulation of tau pathology via the autophagy/proteasome pathway
del Ser-Badia, A.; Soto-Faguas, C. M.; Vecino, R.; Rodriguez-Alvarez, J.; Vicario, C.; Saura, C. A.
10.1101/2023.12.21.572822 — neuroscience — Posted on 2023-12-23
762 Cannabidiol improves learning and memory deficits and alleviates anxiety in 12-month-old SAMP8 Mice
Goodland, M. N.; Banerjee, S.; Niehoff, M. L.; Young, B. J.; Macarathur, H.; Bulter, A. A.; Morley, J. E.; Farr, S. A.
10.1101/2023.12.21.572902 — neuroscience — Posted on 2023-12-23
764 Sequential Transitions of Male Sexual Behaviours Driven by Dual Acetylcholine-Dopamine Dynamics
Miyasaka, A.; Kanda, T.; Nonaka, N.; Terakoshi, Y.; Cherasse, Y.; Ishikawa, Y.; Li, Y.; Takizawa, H.; Seita, J.; Yanagisawa, M.; Sakurai, T.; Sakurai, K.; Liu, Q.
10.1101/2023.12.21.572798 — neuroscience — Posted on 2023-12-23
766 Flavonols improve thermotolerance in tomato pollen during germination and tube elongation by maintaining ROS homeostasis
Postiglione, A.; Delange, A.; Ali, M. F.; Houben, M. K.; Wang, E. Y.; Hahn, S. L.; Roark, C. M.; Davis, M.; Reid, R. W.; Pease, J. B.; Loraine, A. E.; Muday, G. K.
10.1101/2023.12.23.573189 — plant biology — Posted on 2023-12-23
767 Impaired Myofibroblast Proliferation is a Central Feature of Pathologic Post-Natal Alveolar Simplification
Khan, I. S.; Molina, C.; Ren, X.; Auyeung, V. C.; Cohen, M.; Tsukui, T.; Atakilit, A.; Sheppard, D.
10.1101/2023.12.21.572766 — physiology — Posted on 2023-12-23
768 Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension
Wu, D.; Jansen-van Vuuren, R. D.; Dasgupta, A.; Al-Qazazi, R.; Chen, K.-H.; Martin, A. Y.; Mewburn, J. D.; Alizadeh, E.; Lima, P. D.; Jones, O.; Colpman, P. C.; Breault, N. M.; Emon, I. M.; Jedlovcnik, L.; Zhao, Y. Y.; Wells, M.; Sutendra, G.; Archer, S. L.
10.1101/2023.12.21.572836 — pharmacology and toxicology — Posted on 2023-12-23
770 Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients
Ridnourl, L. A.; Cheng, R. Y.; Heinz, W. F.; Pore, M.; Gonzalez, A. L.; Femino, E. L.; Moffat, R.; Wink, A. L.; Imtiaz, F.; Coutinho, L.; Butcher, D.; Edmondson, E. F.; Rangel, C.; Wong, S. T.; Lipkowitz, S.; Glynn, S.; McVicar, D. W.; Vitek, M. P.; Li, X.; Anderson, S. K.; Paolocci, N.; Hewitt, S. M.; Ambs, S.; Billiar, T. R.; Chang, J. C.; Lockett, S. J.; Wink, D. A.
10.1101/2023.12.21.572867 — cancer biology — Posted on 2023-12-23
772 Emergence of synchronised growth oscillations in filamentous fungi
Prakash, P.; Jiang, X.; Richards, L.; Schofield, Z.; Schafer, P.; Polin, M.; Soyer, O. s.; Asally, M. s.
10.1101/2023.12.22.573137 — biophysics — Posted on 2023-12-23
778 Genomic decoding of Theobroma grandiflorum (cupuassu) at chromosomal scale: Evolutionary insights for horticultural innovation
Alves, R. M.; de Abreu, V. A. C.; Oliveira, R. P.; dos Anjos, J. V.; Oliveira, M. d. M.; Silva, S. R.; Paschoal, A. R.; Almeida, S. S.; de Souza, P. A. F.; Ferro, J. A.; Miranda, V. F. O.; Figueira, A.; Domingues, D. S.; Varani, A. M.
10.1101/2023.12.23.573069 — genomics — Posted on 2023-12-23
779 KNL1 and NDC80 represent new universal markers for the detection of functional centromeres in plants
Oliveira, L.; Neumann, P.; Mata-Sucre, Y.; Kuo, Y.-T.; Marques, A.; Schubert, V.; Macas, J.
10.1101/2023.12.21.572763 — genetics — Posted on 2023-12-23
781 Mutations in Fibronectin Dysregulate Chondrogenesis in Corner Fracture Type Spondylometaphyseal Dysplasia
Dinesh, N. E. H.; Rousseau, J.; Mosher, D. F.; Strauss, M.; Mui, J.; Campeau, P. M.; Reinhardt, D. P.
10.1101/2023.12.22.573039 — cell biology — Posted on 2023-12-23
783 A novel KCNJ16 kidney organoid model recapitulates the disease phenotype and shows restoration of lipid accumulation upon treatment with statins
Sendino Garvi, E.; van der Slobbe, G.; Zaal, E. A.; de Baaij, J. H. F.; Hoenderop, J.; Masereeuw, R.; Janssen, M. J.; van Genderen, A. M.
10.1101/2023.12.22.572750 — cell biology — Posted on 2023-12-23
784 A Fully-Automated Senescence Test (FAST) for the high-throughput quantification of senescence-associated markers
Neri, F.; Takajjart, S. N.; Lerner, C. A.; Desprez, P.-Y.; Schilling, B.; Campisi, J.; Gerencser, A. A.
10.1101/2023.12.22.573123 — cell biology — Posted on 2023-12-23
785 A direct estrogenic involvement in the expression of human hypocretin
Li, H.; Chen, X.; Dong, J.; Liu, R.; Duan, J.; Huang, M.; Hu, S.; lu, J.
10.1101/2023.12.21.572761 — neuroscience — Posted on 2023-12-23
787 Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology
Griffiths, J. A.; Yoo, B. B.; Thuy-Boun, P.; Cantu, V.; Weldon, K.; Challis, C.; Sweredoski, M. J.; Chan, K. Y.; Thron, T. M.; Sharon, G.; Moradian, A.; Humphrey, G.; Zhu, Q.; Shaffer, J.; Wolan, D. W.; Dorrestein, P.; Knight, R.; Gradinaru, V.; Mazmanian, S.
10.1101/2021.04.12.439539 — physiology — Posted on 2023-12-23
788 Neonatal enteroids absorb extracellular vesicles from human milk-fed infant digestive fluid
Yung, C.; Kuhn, M.; Armstrong, R. J.; Olyaei, A.; Aloia, M.; Scottoline, B.; Andres, S. F.
10.1101/2023.09.03.556067 — molecular biology — Posted on 2023-12-23
791 Evidence for conservation of primordial 12-hour ultradian gene program in humans under free-living conditions.
Zhu, B.; Liu, S.; David, N. L.; Dion, W.; Doshi, N. K.; Siegel, L. B.; Amorim, T.; Andrews, R. E.; Kumar, G. N.; Li, H.; Irfan, S.; Pesaresi, T.; Sharma, A. X.; Sun, M.; Fazeli, P. K.; Steinhauser, M. L.
10.1101/2023.05.02.539021 — systems biology — Posted on 2023-12-23
792 Arbuscular mycorrhizal fungus Rhizophagus irregularis expresses an outwardly Shaker-like channel involved in potassium nutrition of rice (Oryza sativa L.)
Corratge-Faillie, C.; Matic, L.; Chmaiss, L.; Zhour, H.; Lolivier, J.-P.; Audebert, P.-A.; Bui, T. X.; Seck, M.; Chinachanta, K.; Fizames, C.; Wipf, D.; Sentenac, H.; Very, A.-A.; Courty, P.-E.; Luu, D. T.
10.1101/2022.11.04.515200 — plant biology — Posted on 2023-12-23
796 A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture
Attenborough, T.; Rawlinson, K. A.; Soria, C. L. D.; Ambridge, K.; Sankaranarayanan, G.; Graham, J.; Cotton, J. A.; Doyle, S. R.; Rinaldi, G.; Berriman, M.
10.1101/2023.03.27.533868 — genomics — Posted on 2023-12-23
797 Accounting for unobserved population dynamics and aging error in close-kin mark-recapture assessments
Swenson, J. D.; Brooks, E. N.; Kacev, D.; Boyd, C.; Kinney, M.; Marcy-Quay, B.; Seveque, A.; Feldheim, K.; Komoroske, L. M.
10.1101/2023.02.20.529265 — ecology — Posted on 2023-12-23
798 Reintroduction of resistant frogs facilitates landscape-scale recovery in the presence of a lethal fungal disease
Knapp, R. A.; Wilber, M. Q.; Byrne, A. Q.; Joseph, M. B.; Smith, T. C.; Rothstein, A. P.; Grasso, R. L.; Rosenblum, E. B.
10.1101/2023.05.22.541534 — ecology — Posted on 2023-12-23
804 Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications
Boisen, I. M.; Knudsen, N.; Nielsen, J. E.; Kooij, I.; Bagger, M.; Kaludjerovic, J.; O'Shaughnessy, P.; Andrews, P. W.; Ide, N.; Toft, B. G.; Juul, A.; mehmedbasic, A.; Joergensen, A.; Smith, L. B.; Norman, R.; Rajpert-De Meyts, E.; Lanske, B.; Blomberg Jensen, M.
10.1101/2020.06.25.171355 — molecular biology — Posted on 2023-12-23
807 The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures
Passchier, T. C.; White, J. B. R.; Maskell, D. P.; Byrne, M. J.; Ranson, N. A.; Edwards, T. A.; Barr, J. N.
10.1101/2023.12.07.570572 — microbiology — Posted on 2023-12-23
809 A latent clinical-anatomical dimension relating metabolic syndrome to brain structure and cognition
Petersen, M.; Hoffstaedter, F.; Naegele, F. L.; Mayer, C.; Schell, M.; Rimmele, D. L.; Zyriax, B.-C.; Zeller, T.; Kuehn, S.; Gallinat, J.; Fiehler, J.; Twerenbold, R.; Omidvarnia, A.; Patil, K.; Eickhoff, S. B.; Thomalla, G.; Cheng, B.
10.1101/2023.02.22.529531 — neuroscience — Posted on 2023-12-23
811 GABA Release From Central Amygdala Neurotensin Neurons Differentially Modulates Reward and Consummatory Behavior in Male and Female Mice
Gereau, G. B.; Torruella-Suarez, M. L.; Sizer, S. E.; Xia, M.; Zhou, D.; Wykoff, L. A.; Teklezghi, A. T.; Boyt, K. M.; Alvarez-Pamir, A.; KASH, T. L.; McElligott, Z. A.
10.1101/2023.09.14.557768 — neuroscience — Posted on 2023-12-23
812 Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics
Weinreb, C.; Pearl, J.; Lin, S.; Osman, M. A. M.; Zhang, L.; Annapragada, S.; Conlin, E.; Hoffman, R.; Makowska, S.; Gillis, W. F.; Jay, M.; Ye, S.; Mathis, A.; Mathis, M. W.; Pereira, T.; Linderman, S. W.; Datta, S. R.
10.1101/2023.03.16.532307 — neuroscience — Posted on 2023-12-23
814 Characterizing enteric neurons in Dopamine Transporter (DAT)-Cre reporter micereveals dopaminergic subtypes with dual-transmitter content
Recinto, S.; Premachandran, S.; Mukherjee, S.; McDonald, A.; Allot, A.; Gruenheid, S.; Trudeau, L. E.; Stratton, J. A.
10.1101/2023.06.16.545271 — neuroscience — Posted on 2023-12-23
815 Daily membrane capacitance changes in mouse neurons
Severin, D.; Moreno, C.; Tran, T.; Wesselborg, C.; Shirley, S.; Kirkwood, A.; Golowasch, J.
10.1101/2022.12.09.519806 — neuroscience — Posted on 2023-12-23
816 Noise-induced changes in rat head stability and orientation correlate with dysfunction of otolith irregular afferents
Niwa, M.; Bauer, D.; Anderson, M.; Keller, K.; Kanicki, A.; Altschuler, R.; Stewart, C. E.; King, W. M.
10.1101/2023.10.26.563800 — neuroscience — Posted on 2023-12-23
820 Precise Therapeutic Targeting of Distinct NRXN1+/- Mutations
Fernando, M. B.; Fan, Y.; Zhang, Y.; Kammourh, S.; Murphy, A. N.; Ghorbani, S.; Onatzevitch, R.; Pero, A.; Padilla, C.; Flaherty, E. K.; Prytkova, I. K.; Cao, L.; Williams, S.; Fang, G.; Slesinger, P. A.; Brennand, K.
10.1101/2023.10.28.564543 — neuroscience — Posted on 2023-12-23
821 Modulation of the spatiotemporal dynamics of striatal direct pathway neurons and motor output by mGluR5
Marshall, J. J.; Xu, J.; Yeh, N.-H.; Yun, S.; Nomura, T.; Armstrong, J. N.; Parker, J. G.; Contractor, A.
10.1101/2023.12.20.572676 — neuroscience — Posted on 2023-12-23
822 Autophagy Restricts Tomato Fruit Ripening Via a General Role in Ethylene Repression
Kumaran, G.; Pathak, P. K.; Quandoh, E.; Mursalimov, S. R.; Devi, J.; Tuvia-Alkalai, S.; Leong, J. X.; Schenstnyi, K.; Levin, E.; Üstün, S.; Michaeli, S.
10.1101/2023.12.20.572633 — plant biology — Posted on 2023-12-23
823 Light-phase prednisone promotes glucose oxidation in heart through novel transactivation targets of cardiomyocyte-specific GR and KLF15
El Abdellaoui-Soussi, F.; Durumutla, H. B.; Latimer, H.; Prabakaran, A. D.; McFarland, K.; Miz, K.; Piczer, K.; Werbrich, C.; Jain, M. K.; Haldar, S. M.; Quattrocelli, M.
10.1101/2023.12.18.572210 — physiology — Posted on 2023-12-23
824 Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway
Plugge, S. F.; Ma, H.; van der Vaart, J. Y.; Sprangers, J.; Morsink, F. H. M.; Xanthakis, D.; Jamieson, C.; Keijzer, A. R.; Margaritis, T.; Candelli, T.; Straver, R.; de Ridder, J.; Holstege, F. C. P.; de Leng, W. W. J.; Offerhaus, G. J. A.; Merenda, A.; Maurice, M. M.
10.1101/2023.07.17.548873 — cancer biology — Posted on 2023-12-23
825 CDC20 determines the sensitivity to spindle assembly checkpoint (SAC) inhibitors
Zheng, S.; Raz, L.; Zhou, L.; Cohen-Sharir, Y.; Tian, R.; Wardenaar, R.; Broekhuis, M. J. C.; Suarez Peredo Rodriguez, M. F.; Wobben, S.; van den Brink, A.; Bakker, P.; Foijer, F.; Ben-David, U.
10.1101/2023.12.21.572559 — cancer biology — Posted on 2023-12-23
828 Membrane-embedded polar residues target membrane proteins for degradation by the quality control protease FtsH
Chai-Danino, M.; Ravensary, N.; Onyshchuk, T.; Plohn, M.; Barshap, A. B. D.; Bsoul, A.; Peled-Zehavi, H.; Fluman, N.
10.1101/2023.12.12.571171 — biochemistry — Posted on 2023-12-23
831 Pharmacologically inducing regenerative cardiac cells by small molecule drugs
Zhou, W.; He, K.; Wang, C.; Wang, P.; Wang, D.; Wang, B.; Geng, H.; Lian, H.; Ma, T.; Nie, Y.; Ding, S.
10.1101/2023.10.24.563872 — cell biology — Posted on 2023-12-23
834 Homological landscape of human brain functional sub-circuits
Duong-Tran, D.; Kaufmann, R.; Chen, J.; Wang, X.; Garai, S.; Xu, F.; Bao, J.; Amico, E.; Kaplan, A. D.; Petri, G.; Goni, J.; Zhao, Y.; Shen, L.
10.1101/2023.12.22.573062 — neuroscience — Posted on 2023-12-23
836 Scaling of ventral hippocampal activity during anxiety
Cerquetella, C.; Gontier, C. M.; Forro, T.; Pfister, J.-P.; Ciocchi, S. P.
10.1101/2023.12.22.573072 — neuroscience — Posted on 2023-12-23
838 Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling
Mirzaie, M.; Gholizadeh, E.; Miettinen, J. J.; Ruokoranta, T.; Ianevski, F.; Saarela, J.; Manninen, M.; Miettinen, S.; Heckman, C. A.; Jafari, M.
10.1101/2023.05.25.542238 — cancer biology — Posted on 2023-12-22
839 Predicting the Structural Impact of Human Alternative Splicing
Song, Y.; ZHANG, C.; Omenn, G. S.; O'Meara, M. J.; Welch, J. D.
10.1101/2023.12.21.572928 — bioinformatics — Posted on 2023-12-23
841 Post-synaptic competition between calcineurin and PKA regulates mammalian sleep-wake cycles
Wang, Y.; Cao, S.; Tone, D.; Fujishima, H.; Yamada, R. G.; Ohno, R.-i.; Shi, S.; Matsuzawa, K.; Kaneko, M.; Ukai-Tadenuma, M.; Ukai, H.; Hanashima, C.; Kiyonari, H.; Sumiyama, K.; Ode, K. L.; Ueda, H. R.
10.1101/2023.12.21.572751 — neuroscience — Posted on 2023-12-22
843 Curiosity satisfaction increases event-related potentials sensitive to reward
Rueterbories, T.; Mecklinger, A.; Eschmann, K. C. J.; Crivelli-Decker, J.; Ranganath, C.; Gruber, M. J.
10.1101/2023.05.17.540372 — neuroscience — Posted on 2023-12-22
846 Cyfip2 controls the acoustic startle threshold through FMRP, actin polymerization, and GABAB receptor function.
Deslauriers, J. C.; Ghotkar, R. P.; Russ, L. A.; Jarman, J. M.; Martin, R. M.; Tippett, R. G.; Sumathipala, S. H.; Burton, D. F.; Cole, D. C.; Marsden, K. C.
10.1101/2023.12.22.573054 — neuroscience — Posted on 2023-12-22
847 Bi-allelic variants in WDR47 lead to neuronal loss causing a rare neurodevelopmental syndrome with corpus callosum dysgenesis in humans.
Bayam, E.; Tilly, P.; Collins, S.; Rivera Alvarez, J.; Kannan, M.; Tonneau, L.; Rinaldi, B.; Lecat, R.; Schwaller, N.; Maddirevula, S.; Monteiro, F.; Kitajima, J. P.; Kok, F.; Kato, M.; Hamed, A. A. A.; Salih, M. A.; Al Tala, S.; O Hashem, M.; Tada, H.; Saitsu, H.; Friant, S.; Yüksel, Z.; Nakashima, M.; Alkuraya, F. S.; Yalcin, B.; GODIN, J. D.
10.1101/2023.12.22.572779 — neuroscience — Posted on 2023-12-22
851 FlowAtlas.jl: an interactive tool bridging FlowJo with computational tools in Julia
Coppard, V.; Szep, G.; Georgieva, Z.; Howlett, S. K.; Jarvis, L. B.; Rainbow, D. B.; Suchanek, O.; Needham, E. J.; Mousa, H. S.; Menon, D. K.; Feyertag, F.; Mahbubani, K. T.; Saeb-Parsy, K.; Jones, J. L.
10.1101/2023.12.21.572741 — bioinformatics — Posted on 2023-12-22
853 Development and patterning of a highly versatile visual system in spiders
Baudouin Gonzalez, L.; Schoenauer, A.; Harper, A.; Arif, S.; Leite, D. J.; Steinhoff, P. O. M.; Pechmann, M.; Telizhenko, V.; Pande, A.; Kosiol, C.; McGregor, A. P.; Sumner-Rooney, L.
10.1101/2023.12.22.572789 — developmental biology — Posted on 2023-12-22
854 Characterization and hierarchy of the spermatogonial stem cell compartment in human spermatogenesis by spectral cytometry using a 16-colors panel
Lapoujade, C.; Blanco, M.; Givelet, M.; Gille, A. S.; Allemand, I.; Lenez, L.; Thiounn, N.; Roux, S.; Wolf, J. P.; Patrat, C.; Riou, L.; Barraud-Lange, V.; Fouchet, P.
10.1101/2023.12.21.572912 — developmental biology — Posted on 2023-12-22
857 Development of Pial Collaterals by Extension of Pre-existing Artery Tips
Kumar, S.; Shanavas, N.; Ghosh, S.; Sivaramakrishnan, V.; Dwari, M.; Das, S.
10.1101/2023.12.07.570539 — developmental biology — Posted on 2023-12-22
858 Artemisinin resistance mutations in Pfcoronin impede hemoglobin uptake
Ullah, I.; Farringer, M. A.; Burkhard, A. Y.; Hathaway, E.; Willett, B. C.; Khushu, M.; Shin, S. H.; Sharma, A. I.; Shao, K. L.; Martin, M. C.; Dvorin, J. D.; Hartl, D. L.; Volkman, S. K.; Bopp, S.; Absalon, S.; Wirth, D. F.
10.1101/2023.12.22.572193 — cell biology — Posted on 2023-12-22
860 PARP inhibitors enhance reovirus-mediated cell killing through the death-inducing signaling complex (DISC) with an associated NF-kappa B-regulated immune response.
Kyula-Currie, J.; Roulstone, V.; Wright, J.; Butera, F.; Legrand, A.; Elliott, R.; McLaughlin, M.; Bozhanova, G.; Krastev, D. B.; Pettitt, S.; Tenev, T.; Dillon, M. T. B.; Foo, S.; Patin, E. C.; Jennings, V.; Chan, C.; Appleton, E.; Pedersen, M.; Rullan, A.; Choudhary, J.; Bakal, C.; Meier, P.; Lord, C. J.; Melcher, A.; Harrington, K. J.
10.1101/2023.12.21.572541 — cancer biology — Posted on 2023-12-22
861 The tumour suppressor Fat1 is dispensable for normal murine haematopoiesis
Zhang, Q.; Li, M. K.; Hu, X. Y.; Wang, Y. Y.; Zhao, P. P.; Cheng, L. N.; Yu, R. H.; Zhang, X. D.; Chen, S.; Zhu, Z. M.; de Bock, C. E.; Thorne, R. F.
10.1101/2023.12.20.572284 — cancer biology — Posted on 2023-12-22
862 How to control unpredictable others in court-net sports
Yamamoto, Y.; Yokoyama, K.; Kijima, A.; Okumura, M.; Shima, H.; Gohara, K.
10.1101/2023.12.20.572699 — biophysics — Posted on 2023-12-22
865 SOAPy: a Python package to dissect spatial architecture, dynamics and communication
Wang, H.; Li, J.; Jing, S.; Lin, P.; Li, Y.; Zhang, H.; Chen, Y.; Wang, Z.; Li, H.
10.1101/2023.12.21.572725 — bioinformatics — Posted on 2023-12-22
867 Resource-efficient nitrogen removal from source separated urine with partial nitritation/anammox in a membrane aerated biofilm reactor
Timmer, M. J.; De Paepe, J.; Van Winckel, T.; Spiller, M.; Spacova, I.; De Paepe, K.; Pintelon, I.; Lebeer, S.; De Vos, W.; Lasseur, C.; Ganigue, R.; Udert, K.; Vlaeminck, S. E.
10.1101/2023.12.21.572732 — bioengineering — Posted on 2023-12-22
871 Overlapping and Distinct Mechanisms of Effective Neoantigen Cancer Vaccines and Immune Checkpoint Therapy
Keshari, S.; Shavkunov, A. S.; Miao, Q.; Saha, A.; Williams, C. D.; Highsmith, A. M.; Pineda, J. E.; Alspach, E.; Hu, K.; Pauken, K. E.; Chen, K.; Gubin, M. M.
10.1101/2023.12.20.570816 — immunology — Posted on 2023-12-22
874 CSF plasma cell expansion in LGI1-/CASPR2-autoimmune encephalitis is associated with loss of regulatory MAIT cells
Esser, D.; Mueller-Miny, L.; Heming, M.; Paunovic, M.; van Duijn, M.; Cabrera, L. A.; Mair, K.; Strippel, C.; Raeuber, S.; Bindels, E.; Dargvainiene, J.; Wiendl, H.; Meuth, S.; Bauer, J.; Melzer, N.; Titulaer, M.; Leypoldt, F.; Meyer zu Hoerste, G.; EMC-AIE Study group,
10.1101/2023.12.21.572754 — neuroscience — Posted on 2023-12-22
876 Transcriptional and Cellular Response of hiPSC-derived Microglia-Neural Progenitor Co-Cultures Exposed to IL-6
Couch, A. C. M.; Brown, A.; Taylor, M.; Sichlinger, L.; Matuleviciute, R.; Srivastava, D. P.; Vernon, A. C.
10.1101/2023.12.21.572748 — neuroscience — Posted on 2023-12-22
878 Tittle: An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfection
Fontes, J. L. M.; Khouri, R.; Reinaldo, L. G. C.; Hassegawa, E. M. A.; Meneses Filho, A. J.; de Melo, C. V. B.; Ramos, P. I. P.; de Deus Moura, R.; Pagliari, C.; Santos, M.; Araujo, R. J. C.; Van Weyenbergh, J.; de Freitas, L. A. R.; Costa, C. H. N.; dos-Santos, W. L. C.
10.1101/2023.12.21.572737 — pathology — Posted on 2023-12-22
880 Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice.
Gatti, D. M.; Tyler, A. L.; Mahoney, J. M.; Churchill, G. A.; Yener, B.; Koyuncu, D.; Gurcan, M. N.; Niazi, M. K. K.; Tavolara, T.; Gower, A. C.; Dayao, D.; McGlone, E.; Ginese, M.; Specht, A.; Alsharaydeh, A.; Tessier, P. A.; Kurtz, S.; Elkins, K.; Kramnik, I.; Beamer, G.
10.1101/2023.12.21.572738 — genetics — Posted on 2023-12-22
881 Microbial aromatic amino acid metabolism is modifiable in fermented food matrices to promote bioactivity
Kasperek, M. C.; Velasquez Galeas, A.; Caetano-Silva, M. E.; Xie, Z.; Ulanov, A. V.; La Frano, M. R.; Devkota, S.; Miller, M. J.; Allen, J. M.
10.1101/2023.12.21.572869 — microbiology — Posted on 2023-12-22
882 Lethality of West Nile virus strains in a mouse model
Siniavin, A. E.; Dolzhikova, I. V.; Pochtovyi, A. A.; Reshetnikov, D. A.; Gushchin, V. A.
10.1101/2023.12.22.572994 — microbiology — Posted on 2023-12-22
883 IRAK4 autophosphorylation controls inflammatory signaling by activating IRAK oligomerization
Srikanth, N.; Deliz-Aguirre, R.; Gola, D. K.; Bilay, M.; Ziska, E.; Taylor, M. J.
10.1101/2023.12.21.572799 — immunology — Posted on 2023-12-22
884 A system-wide analysis of lipid transfer proteins delineates lipid mobility in human cells
Titeca, K.; Chiapparino, A.; Turei, D.; Zukowska, J.; van Ek, L.; Moqadam, M.; Triana, S.; Nielsen, I. O.; Gehin, C.; Maeda, K.; Alexandrov, T.; Saez-Rodriguez, J.; Reuter, N.; Hennrich, M. L.; Gavin, A.-C.
10.1101/2023.12.21.572821 — biochemistry — Posted on 2023-12-22
885 Calcium binding site in AA10 LPMO from Vibrio cholerae suggests modulating effects during environment survival and infection
Montserrat-Canals, M.; Bjerregaard-Andersen, K.; Sorensen, H. V.; Cordara, G.; Vaaje-Kolstad, G.; Krengel, U.
10.1101/2023.12.22.573012 — biochemistry — Posted on 2023-12-22
887 A suicidal and extensively disordered luciferase with a bright luminescence
Dijkema, F. M.; Escarpizo-Lorenzana, M. I.; Nordentoft, M. K.; Rabe, H. C.; Sahin, C.; Landreh, M.; Branca, R. M.; Sorensen, E. S.; Christensen, B. S.; Prestel, A.; Teilum, K.; Winther, J. R.
10.1101/2023.12.21.572513 — biochemistry — Posted on 2023-12-22
888 Plant genetic bases explaining microbiota diversity shed light into a novel holobiont generalist gene theory
Maillet, L.; Norest, M.; Kautsky, A.; Geraci, A.; Oddo, E.; Troia, A.; GUILLERM-ERCKELBOUDT, A.-Y.; Falentin, C.; Rousseau-Gueutin, M.; Chevre, A.-M.; Istace, B.; Cruaud, C.; Belser, C.; Aury, J.-M.; Schicchi, R.; Frachon, L.; Bartoli, C.
10.1101/2023.12.22.572874 — evolutionary biology — Posted on 2023-12-22
890 UVB radiation suppresses Dicer expression through β-catenin
AKTARY, Z.; PETIT, V.; BERLIN, I.; CHARENCHAON, N.; SAGE, E.; BERTRAND, J. U.; LARUE, L.
10.1101/2023.12.22.572980 — molecular biology — Posted on 2023-12-22
891 Fully automated workflow for integrated sample digestion and Evotip loading enabling high-throughput clinical proteomics
Kverneland, A. H.; Harking, F.; Vej-Nielsen, J. M.; Huusfeldt, M.; Bekker-Jensen, D. B.; Svane, I. M.; Bache, N.; Olsen, J. V.
10.1101/2023.12.22.573056 — molecular biology — Posted on 2023-12-22
893 Human telomere length is chromosome specific and conserved across individuals
Greider, C. W.; Karimian, K.; Groot, A.; Huso, V.; Kahidi, R.; Tan, K.-T.; Sholes, S.; Keener, R. W.; McDyer, J. F.; Alder, J. K.; Li, H. K.; Rechtsteiner, A.
10.1101/2023.12.21.572870 — molecular biology — Posted on 2023-12-22
894 RNA 5' terminal nucleotide determines the strength of the RIG-I/IFN signaling pathway
Wolczyk, M.; Szymanski, J.; Trus, I.; Naz, Z.; Bolembach, A.; Choudhury, N. R.; Tame, T.; Konuc, C.; Nowak, E.; Spanos, C.; Rappsilber, J.; Michlewski, G.
10.1101/2023.12.22.573000 — molecular biology — Posted on 2023-12-22
895 Unravelling Silicon's Transcriptomic Armor in Soybean against Macrophomina phaseolina causing Charcoal Rot Disease
Jadhav, P. V.; Magar, S. G.; Sharma, P. K.; Vaidya, E. R.; Moharil, M. P.; Jaiswal, S.; Nichal, S. S.; Iquebal, M. A.; Ghawade, R. S.; Kawar, P. G.; Jadhav, P. R.; Sakhare, S. B.; Ghorade, R. B.; Deshmukh, R.; Kumar, D.; Sonah, H.; Torop, E. A.; Kharche, V. K.; Dani, R. G.; Mane, S. S.
10.1101/2023.12.22.572986 — microbiology — Posted on 2023-12-22
897 Multi-omics investigations uncover unique pathogenic markers in clinical Klebsiella pneumoniae that could be leveraged as novel antimicrobial targets
Swiatek, L.-S.; Surmann, K.; Eger, E.; Muller, J. U.; Salazar, M. G.; Guenther, S.; Werner, G.; Hubner, N.-O.; Bohnert, J. A.; Becker, K.; Heiden, S. E.; Volker, U.; Schwabe, M.; Schaufler, K.
10.1101/2023.12.22.573023 — microbiology — Posted on 2023-12-22
899 Role of the osaA gene in Aspergillus fumigatus development, secondary metabolism and virulence.
Dabholkar, A.; Pandit, S.; Devkota, R.; Dhingra, S.; Lorber, S.; Puel, O.; Calvo, A. M.
10.1101/2023.12.21.572920 — microbiology — Posted on 2023-12-22
900 Alternate routes to mnm5s2U synthesis in Gram-positive bacteria
Jaroch, M.; Sun, G.; Tsui, H.-C. T.; Reed, C.; Sun, J.; Joerg, M.; Winkler, M. E.; Rice, K. C.; Stich, T. A.; Dedon, P.; Dos Santos, P. C.; de Crecy-Lagard, V.
10.1101/2023.12.21.572861 — microbiology — Posted on 2023-12-22
901 Metabolism of ʟ -arabinose converges with virulence regulation to promote enteric pathogen fitness
Cottam, C.; White, R. T.; Beck, L. C.; Stewart, C. J.; Beatson, S. A.; Lowe, E. C.; Grinter, R.; Connolly, J. P.
10.1101/2023.12.21.572775 — microbiology — Posted on 2023-12-22
902 The RNA-binding protein RbpB is a central regulator of polysaccharide utilization in gut Bacteroides
Ruttiger, A.-S.; Ryan, D.; Spiga, L.; Lamm-Schmidt, V.; Prezza, G.; Reichardt, S.; Barquist, L.; Faber, F.; Zhu, W.; Westermann, A. J.
10.1101/2023.12.22.572801 — microbiology — Posted on 2023-12-22
903 Metabolomics profiling reveals distinct, sex-specific signatures in the serum and brain metabolomes in the mouse models of Alzheimer's disease
Pandey, R. S.; Arnold, M.; Batra, R.; Krumsiek, J.; Kotredes, K. P.; Garceau, D.; Williams, H.; Sasner, M. J.; Howell, G. R.; Kaddurah-Daouk, R.; Carter, G. W.
10.1101/2023.12.22.573059 — neuroscience — Posted on 2023-12-22
905 Three-step mechanism of promoter escape by RNA polymerase II
Zhan, Y.; Grabbe, F.; Oberbeckmann, E.; Dienemann, C.; Cramer, P.
10.1101/2023.12.22.572998 — biochemistry — Posted on 2023-12-22
906 Use of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 angstrom
Lin, H. H.; Wang, C.-H.; Wu, Y.-M.; Huang, S.-H.; Lin, S. S.-Y.; Kato, T.; Namba, K.; Hosogi, N.; Song, C.; Murata, K.; Yen, C.-H.; Hsu, T.-L.; Wong, C.-H.; Tu, I.-P.; Chang, W.-H.
10.1101/2023.12.21.571784 — biochemistry — Posted on 2023-12-22
907 Cytosolic acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA
Zeaiter, N.; Belot, L.; Cunin, V.; Abi Nahed, R.; Tokarska-Schlattner, M.; Le Gouellec, A.; Petosa, C.; Khochbin, S.; Schlattner, U.
10.1101/2023.12.21.572516 — biochemistry — Posted on 2023-12-22
908 Structure of the minor spliceosomal U11 snRNP
Zhao, J.; Peter, D.; Brandina, I.; Liu, X.; Galej, W. P.
10.1101/2023.12.22.573053 — biochemistry — Posted on 2023-12-22
910 Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations
Grieco, A.; Boneta, S.; Gavira, J. A.; Pey, A. L.; Basu, S.; Orlans, J.; de Sanctis, D.; Medina, M.; Martin Garcia, J. M.
10.1101/2023.12.21.572834 — biochemistry — Posted on 2023-12-22
911 Genomic analysis of Staphylococcus aureus isolates from bacteremia reveals genetic features associated with the COVID-19 pandemic
Sanchez-Osuna, M.; Pedrosa, M.; Bierge, P.; Gomez-Sanchez, I.; Alguacil-Guillen, M.; Espasa, M.; Erill, I.; Gasch, O.; Pich, O. Q.
10.1101/2023.12.22.572975 — genomics — Posted on 2023-12-22
912 In vivo single-molecule imaging of RecB reveals efficient repair of DNA damage in Escherichia coli
Lepore, A.; Thedie, D.; McLaren, L.; Azeroglu, B.; Pambos, O. J.; Kapanidis, A. N.; El Karoui, M.
10.1101/2023.12.22.573010 — molecular biology — Posted on 2023-12-22
913 Host-Pathogen Interactions in the Plasmodium-Infected Mouse Liver at Spatial and Single-Cell Resolution
Hildebrandt, F.; Urrutia-Iturritza, M.; Zwicker, C.; Vanneste, B.; Van Hul, N.; Semle, E.; Pascini, T.; Saarenpaa, S.; He, M.; Andersson, E. R.; Scott, C. L.; Vega-Rodriguez, J.; Lundeberg, J.; Ankarklev, J.
10.1101/2023.12.22.573046 — molecular biology — Posted on 2023-12-22
914 DNA nicks in both leading and lagging strand templates can trigger break-induced replication
Xu, Y.; Laksir, Y.; Morrow, C. A.; Taylor, K.; Tsiappourdhi, C.; Collins, P.; Jia, S.; Andreadis, C.; Whitby, M.
10.1101/2023.12.22.573028 — molecular biology — Posted on 2023-12-22
915 Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants
Ke, Z.; Peacock, T. P.; Brown, J. C.; Sheppard, C. M.; Croll, T. I.; Kotecha, A.; Goldhill, D. H.; Barclay, W. S.; Briggs, J. A.
10.1101/2023.12.21.572824 — microbiology — Posted on 2023-12-22
916 Phylogenetic distribution and experimental characterization of corrinoid production and dependence in soil bacterial isolates
Alvarez-Aponte, Z. I.; Govindaraju, A. M.; Hallberg, Z. F. F.; Nicolas, A. M.; Green, M. A.; Mok, K. C.; Fonseca-Garcia, C.; Coleman-Derr, D.; Brodie, E. L.; Carlson, H. K.; Taga, M. E.
10.1101/2023.12.21.572947 — microbiology — Posted on 2023-12-22
917 Histone H2A variant H2A.B is enriched in transcriptionally active HSV-1 lytic chromatin
Flores Cortes, E.; Saddoris, S.; Owens, A. K.; Gibeault, R.; Depledge, D. P.; Schang, L. M.
10.1101/2023.12.22.573075 — microbiology — Posted on 2023-12-22
920 Rab3 mediates cyclic AMP-dependent presynaptic plasticity and olfactory learning
Sachidanandan, D.; Aravamudhan, A.; Mrestani, A.; Nerlich, J.; Lamberty, M.; Hasenauer, N.; Ehmann, N.; Pauls, D.; Seubert, T.; Maiellaro, I.; Selcho, M.; Heckmann, M.; Hallermann, S.; Kittel, R. J.
10.1101/2023.12.21.572589 — neuroscience — Posted on 2023-12-22
922 Chloroplast Methyltransferase Homolog RMT2 is Involved in Photosystem I Biogenesis
Kim, R. G.; Huang, W.; Findinier, J.; Bunbury, F.; Redekop, P.; Shrestha, R.; Vilarrasa-Blasi, J.; Jinkerson, R. E.; Fakhimi, N.; Fauser, F.; Jonikas, M. C.; Onishi, M.; Xu, S.-L.; Grossman, A. R.
10.1101/2023.12.21.572672 — plant biology — Posted on 2023-12-22
923 A common regulatory switch controls a suite of C4 traits in multiple cell types
Camo-Escobar, D.; Alcala-Gutierrez, C.; Palafox-Figueroa, E.; Guillotin, B.; Hernandez-Coronado, M.; Coyac-Rodriguez, J. L.; Cerbantez-Bueno, V. E.; Velez-Ramirez, A.; de Folter, S.; Birnbaum, K. D.; Ortiz-Ramirez, C. H.
10.1101/2023.12.21.572850 — plant biology — Posted on 2023-12-22
925 The Zea mays PeptideAtlas; a new maize community resource
van Wijk, K. J.; Leppert, T.; Sun, Z.; Guzchenko, I.; Debley, E.; Sauermann, G.; Routray, P.; Mendoza, L.; Sun, Q.; Deutsch, E. W.
10.1101/2023.12.21.572651 — plant biology — Posted on 2023-12-22
927 Intronic miR-6741-3p is involved in oral squamous cell carcinoma pathogenesis by targeting the oncogene SRSF3
More, D. A.; Singh, N.; Mishra, R.; Muralidharan, H. P.; Gopinath, K. S.; Gopal, C.; Kumar, A.
10.1101/2023.12.20.572638 — cancer biology — Posted on 2023-12-22
929 Metagenomic detection and genetic characterization of human sapovirus among children in Nigeria
George, U. E.; Faleye, T. O. C.; De Coninck, L.; Agbaje, S. T.; Ifeorah, I. M.; Onoja, B. A.; Oni, E. I.; Olayinka, O. A.; Ajileye, T. G.; Oragwa, A. O.; Akinleye, T. E.; Popoola, B. O.; Osasona, O. G.; Olayinka, O. T.; George, O. A.; Muhammad, A. I.; Komolafe, I.; Adeniji, J. A.; Matthijnssens, J.; Adewumi, O. M.
10.1101/2023.12.20.572641 — molecular biology — Posted on 2023-12-22
930 An AAV capsid reprogrammed to bind human Transferrin Receptor mediates brain-wide gene delivery
Huang, Q.; Chan, K. Y.; Lou, S.; Keyes, C.; Wu, J.; Botticello-Romero, N. R.; Zheng, Q.; Johnston, J.; Mills, A.; Brauer, P. P.; Clouse, G.; Pacouret, S.; Harvey, J. W.; Beddow, T.; Hurley, J. K.; Tobey, I. G.; Powell, M.; Chen, A. T.; Barry, A. J.; Eid, F.-E.; Chan, Y. A.; Deverman, B. E.
10.1101/2023.12.20.572615 — neuroscience — Posted on 2023-12-22
932 Role of the metallo-reductase FADING and vacuolinos in anthocyanin degradation in flowers and fruits.
Passeri, V.; Li, S.; Strazzer, P.; Martinez-Calvo, E.; Senden, E.; Guzzo, F.; Commisso, M.; Spelt, C.; Vandenbussche, M.; Bliek, M.; Verweij, W.; Koes, R.; Quattrocchio, F. M.
10.1101/2023.12.21.569356 — plant biology — Posted on 2023-12-22
933 On the mechanism for winter stem pressure build-up in walnut tree
Bozonnet, C.; Saudreau, M.; Badel, E.; Charrier, G.; Ameglio, T.
10.1101/2023.12.21.572762 — plant biology — Posted on 2023-12-22
940 Porcine sapovirus protease controls the innate immune response and targets TBK1
Georgana, I.; Hosmillo, M.; Jahun, A. S.; Emmott, E.; Sorgeloos, F.; Cho, K.-O.; Goodfellow, I. G.
10.1101/2023.12.21.572846 — microbiology — Posted on 2023-12-22
941 Group size modulates kinship dynamics and selection on social traits
He, P.; Weiss, M. N.; Ellis, S.; Franks, D. W.; Cant, M. A.; Croft, D. P.; Johnstone, R. A.
10.1101/2023.12.22.573047 — evolutionary biology — Posted on 2023-12-22
944 MRTF promotes breast cancer cell motility through SRF-dependent upregulation of DIAPH3 expression
Eder, I.; Yu, V.; Chen, F.; Gau, D.; Joy, M.; Lucas, P.; Boone, D.; LEE, A. V.; Roy, P.
10.1101/2023.12.21.572883 — cell biology — Posted on 2023-12-22
945 Intracellular pH modulates vimentin remodeling in response to oxidants
Martinez, A. E.; Gonzalez-Jimenez, P.; Vidal-Verdu, C.; Pajares, M. A.; Perez-Sala, D.
10.1101/2023.12.21.572888 — cell biology — Posted on 2023-12-22
946 Nuclear membrane protein Bqt4 maintains nuclear envelope integrity by recruiting phosphatidic acid
Hirano, Y.; Sato, T.; Miura, A.; Kubota, Y.; Shindo, T.; Fukase, K.; Fukagawa, T.; Kabayama, K.; Haraguchi, T.; Hiraoka, Y.
10.1101/2023.12.21.572941 — cell biology — Posted on 2023-12-22
948 Identification of a Novel Ferroptosis Inducer with Dual Modulatory Effects on GPX4 Activity and Stability
Wang, J.; Liao, L.; Yang, B.; Miao, B.; Li, B.; Ma, X.; Fitz, A.; Wu, S.; He, J.; Zhang, Q.; Ji, S.; Jin, G.; Zhang, J.; Bernards, R.; Qin, W.; Sun, C.; Wang, C.
10.1101/2023.12.22.572948 — cell biology — Posted on 2023-12-22
955 The Reelin Receptor ApoER2 is a Cargo for the Adaptor Protein Complex AP-4: Implications for Hereditary Spastic Paraplegia.
Caracci, M.; Pizarro, H.; Alarcon-Godoy, C.; Fuentealba, L. M.; Farfan, P.; De Pace, R.; Santibanez, N.; Cavieres, V. A.; Pastor, T.; Bonifacino, J.; Mardones, G.; Marzolo, M.-P.
10.1101/2023.12.21.572896 — cell biology — Posted on 2023-12-22
958 Comprehensive Assessment of Ischemic Stroke in Nonhuman Primates: Neuroimaging, Behavioral, and Serum Proteomic Analysis
Li, G.; Lan, L.; He, T.; Tang, Z.; Liu, S.; Li, Y.; Huang, Z.; Guan, Y.; Li, X.; Zhang, Y.; Lai, H.-Y.
10.1101/2023.12.20.572532 — neuroscience — Posted on 2023-12-22
959 The multiscale topological organization of the functional brain network in adolescent PTSD
Corredor, D.; Segobin, S.; Hinault, T. T.; Eustache, F.; Dayan, J.; Guillery, B.; Naveau, M.
10.1101/2023.12.21.572743 — neuroscience — Posted on 2023-12-22
961 Deep super-resolution imaging of thick tissue using structured illumination with adaptive optics
Wang, J.; Stoychev, D.; Phillips, M.; Pinto, D. M. S.; Parton, R. M.; Hall, N.; Titlow, J.; Faria, A. R.; Wincott, M.; Gala, D.; Gerondopoulos, A.; Irani, N.; Dobbie, I.; Schermelleh, L.; Booth, M.; Davis, I.
10.1101/2023.12.21.572818 — cell biology — Posted on 2023-12-22
962 Mitochondria alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarks
Eysert, F.; Kinoshita, P. F.; Lagarde, J.; Lacas-Gervais, S.; Xicota, L.; Dorothee, G.; Bottlaender, M.; Checler, F.; Potier, M.-C.; Sarazin, M.; Chami, M.
10.1101/2023.12.21.570579 — cell biology — Posted on 2023-12-22
963 Lamin B Receptor Upregulation in Metastatic Melanoma Causes Cholesterol-Mediated Nuclear Envelope Fragility
Baird, M. A.; Fischer, R. S.; Jewett, C. E.; Malide, D.; Cartagena-Rivera, A. X.; Waterman, C. M.
10.1101/2023.12.21.572889 — cell biology — Posted on 2023-12-22
966 DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time
Relovska, S.; Wang, H.; Zhang, X.; Fernandez-Tussy, P.; Jeong, K.; Choi, J.; Suarez, Y.; McDonald, J.; Fernandez-Hernando, C.; Chung, J.-J.
10.1101/2023.12.21.572851 — cell biology — Posted on 2023-12-22
967 PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
Sundarraj, J.; Patel, M.; Boulet, F.; Aziz, H.; Brooke, G.; Tummala, H.; Madapura, P.
10.1101/2022.12.02.518862 — molecular biology — Posted on 2023-12-22
969 SMC motor proteins extrude DNA asymmetrically and contain a direction switch
Barth, R.; Davidson, I.; van der Torre, J.; Taschner, M.; Gruber, S.; Peters, J.-M.; Dekker, C.
10.1101/2023.12.21.572892 — molecular biology — Posted on 2023-12-22
971 Overexpression of tomato SlBBX16 and SlBBX17 impacts fruit development and GA metabolism
Dusi, V.; Pennisi, F.; Fortini, D.; Atares, A.; Wenkel, S.; Molesini, B.; Pandolfini, T.
10.1101/2023.08.12.553068 — plant biology — Posted on 2023-12-22
972 Age-dependent RGS5 loss in pericytes induces cardiac dysfunction and fibrosis in the heart
Tamiato, A.; Tombor, L. S.; Fischer, A.; Muhly-Reinholz, M.; Vanicek, L. R.; Togru, B. N.; Neitz, J.; Glaser, S. F.; Merten, M.; Rodriguez Morales, D.; Kwon, J.; Klatt, S.; Schuhmacher, B.; Guenther, S.; Abplanalp, W. T.; John, D.; Fleming, I.; Wettschureck, N.; Dimmeler, S.; Luxan, G.
10.1101/2023.12.08.570774 — physiology — Posted on 2023-12-22
973 Dehydrozaluzanin C- derivative protects septic mice by alleviating over-activated inflammatory response and promoting the phagocytosis of macrophages
Zou, y.; Xiang, t.; Xu, l.; Zhang, h.; Ma, y.; Zhang, l.; Zhou, c.; Wu, x.; Huang, q.; Lei, b.; Mu, j.; Qin, X.; Jiang, X.; Zheng, y.
10.1101/2023.11.01.565192 — pharmacology and toxicology — Posted on 2023-12-22
976 Electrophysiological Mechanisms in the Anterior Insula Cortex during Reward Expectancy
Yang, L.; Lehongre, K.; Ye, H.; Yu, X.; Navarro, V.; Cheng, S.; Lin, Z.; Axmacher, N.; Wang, S.; Zhang, H.
10.1101/2023.09.19.558205 — neuroscience — Posted on 2023-12-22
978 A layer-specific model of cortical sensory aging
Liu, P.; Doehler, J.; Henschke, J. U.; Northall, A.; Serian, A.; Schwarzkopf, D. S.; Speck, O.; Pakan, J. M. P.; Kuehn, E.
10.1101/2023.12.01.567841 — neuroscience — Posted on 2023-12-22
983 Phase diversity-based wavefront sensing for fluorescence microscopy
Johnson, C.; Guo, M.; Schneider, M. C.; Su, Y.; Khuon, S. C.; Reiser, N.; Wu, Y.; La Riviere, P. J.; Shroff, H.
10.1101/2023.12.19.572369 — bioengineering — Posted on 2023-12-22
984 Maximizing glycoproteomics results through an integrated PASEF workflow
Baerenfaenger, M.; Post, M. A.; Zijlstra, F. S. M.; van Gool, A. J.; Lefeber, D. J.; Wessels, H. J.
10.1101/2023.12.21.570555 — biochemistry — Posted on 2023-12-22
986 An important role for triglyceride in regulating spermatogenesis
Chao, C. F.; Pesch, Y.-Y.; Yu, H.; Wang, C.; Aristizabal, M. J.; Huan, T.; Tanentzapf, G.; Rideout, E.
10.1101/2022.12.16.520841 — developmental biology — Posted on 2023-12-22
987 Temporal transcriptomic dynamics in developing macaque neocortex
Xu, L.; yuan, z.; Zhou, J.; Zhao, Y.; Liu, W.; Lu, S.; He, Z.; Qiang, B.; Shu, P.; Chen, Y.; Peng, X.
10.1101/2023.07.13.548828 — developmental biology — Posted on 2023-12-22
992 Tracking the behavioral and neural dynamics of semantic representations through negation
Zuanazzi, A.; Ripolles, P.; Lin, W. M.; Gwilliams, L.; King, J.-R.; Poeppel, D.
10.1101/2022.10.14.512299 — neuroscience — Posted on 2023-12-22
993 Dynamics of Brain Lateralization during Chinese Natural Speech Processing under the Influence of Sex Hormones: a 7T fMRI study
Zhang, R.; Geng, S.; Zheng, X.; Guo, W.; Lo, C.-Y. Z.; Zhang, J.; Chang, X.; Wu, X.; Zhang, J.; Cao, M.; Feng, J.
10.1101/2023.11.29.569155 — neuroscience — Posted on 2023-12-22
997 Feeding Behavior Modifies Daily Rhythms in Autonomic Signaling and Core Body Temperature to Shape 24-hour Rhythms in Cardiac Electrophysiology
Ono, M.; Burgess, D.; Johnson, S. R.; Elayi, C. S.; Esser, K. A.; Seward, T. S.; Boychuk, C. A.; Stalcup, R. A.; Carreno, A. P.; Prabhat, A.; Schroder, E.; Delisle, B. P.
10.1101/2023.11.02.565372 — physiology — Posted on 2023-12-22
998 Shared features of blastula and neural crest stem cells evolved at the base of vertebrates
York, J.; Rao, A.; Huber, P. B.; Schock, E. N.; Montequin, A.; Rigney, S.; LaBonne, C.
10.1101/2023.12.21.572714 — evolutionary biology — Posted on 2023-12-22
1000 Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models
Lara-Saez, I.; Mencia, A.; Recuero, E.; Li, Y.; Garcia, M.; Oteo, M.; Gallego, M. I.; Enguita, A. B.; de Prado-Verdun, D.; A, S.; Wang, W.; Garcia-Escudero, R.; Murillas, R.; Santos, M.
10.1101/2023.12.21.572771 — cancer biology — Posted on 2023-12-21
1006 (CA)n oligonucleotides correct RNA mis-splicing in TDP-43 pathology
Wang, C.; Terrigno, M.; Joenson, L.; Li, M.; Schroeter, M.; Nordbo, B.; Chyzynska, K.; Weile, C.; Bastien, J.; Mogensen, M. B.; Seidel, A. S.; Hagedorn, P. H.; Jagasia, R.; Vikesaa, J.
10.1101/2023.12.21.572777 — molecular biology — Posted on 2023-12-21
1007 Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy
Iyer, D. P.; Moyon, L.; Ringeling, F. R.; Cheng, C.-Y.; Wittler, L.; Canzar, S.; Marsico, A.; Bulut-Karslioglu, A.
10.1101/2023.12.20.572612 — molecular biology — Posted on 2023-12-21
1009 Translational mapping of spatially resolved transcriptomes in human and mouse pulmonary fibrosis
Franzen, L.; Olsson Lindvall, M.; Hühn, M.; Ptasinski, V.; Setyo, L.; Keith, B.; Collin, A.; Oag, S.; Volckaert, T.; Borde, A.; Lundeberg, J.; Lindgren, J.; Belfield, G.; Jackson, S.; Ollerstam, A.; Stamou, M.; Stahl, P. L.; Hornberg, J. J.
10.1101/2023.12.21.572330 — molecular biology — Posted on 2023-12-21
1012 Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study
Durairaj, J.; Follonier, O.; Leuzinger, K.; Alexander, L. T.; Wilhelm, M.; Pereira, J.; Hillenbrand, C. A.; Weissbach, F.; Schwede, T.; Hirsch, H. H.
10.1101/2023.12.21.572635 — microbiology — Posted on 2023-12-21
1013 Iron depletion has different consequences on the growth and survival of Toxoplasma gondii strains
Renaud, E. A.; Maupin, A. J. M.; Bordat, Y.; Graindorge, A.; Berry, L.; Besteiro, S.
10.1101/2023.12.21.572787 — microbiology — Posted on 2023-12-21
1014 Engineered Skin Microbiome Reduces Mosquito Attraction to Mice
Liu, F.; Coutinho-Abreu, I. V.; Raban, R.; Nguyen, T.; Dimas, A.; Merriman, J.; Akbari, O.
10.1101/2023.12.20.572663 — microbiology — Posted on 2023-12-21
1016 LLPS condensates of Fha initiate the inside-out assembly of the type VI secretion system
Pei, T.-T.; An, Y.; Wang, X.-Y.; Luo, H.; Kan, Y.; Li, H.; Tang, M.-X.; Ye, Z.-Y.; Liang, J.-X.; Jian, T.; Zheng, H.-Y.; Wang, Z.-H.; Liang, X.; Zhang, M.; Liu, X.; Dong, T.
10.1101/2023.12.21.572528 — microbiology — Posted on 2023-12-21
1019 Tracking SARS-CoV-2 variants of concern in wastewater: an assessment of nine computational tools using simulated genomic data
Sutcliffe, S. G.; Kraemer, S. A.; Ellmen, I.; Knapp, J. J.; Overton, A. K.; Nash, D.; Nissimov, J. I.; Charles, T. C.; Dreifuss, D.; Topolsky, I.; Baykal, P. I.; Fuhrmann, L.; Jablonski, K. P.; Beerenwinkel, N.; Levy, J. I.; Olabode, A. S.; Becker, D. G.; Gugan, G.; Britnell, E.; Poon, A. F. Y.; Valieris, R.; Drummond, R. D.; Defelicibus, A.; Dias-Neto, E.; Rosales, R. A.; Tojal da Silva, I.; Orfanou, A.; Psomopoulos, F.; Pechlivanis, N.; Pipes, L.; Chen, Z.; Baaijens, J. A.; Baym, M.; Shapiro, B. J.
10.1101/2023.12.20.572426 — bioinformatics — Posted on 2023-12-21
1021 Identification of a short, single site matriglycan that maintains neuromuscular function in the mouse
Yang, T.; Chandel, I.; Gonzales, M.; Okuma, H.; Prouty, S. J.; Zarei, S.; Joseph, S.; Garringer, K. W.; Ocampo Landa, S.; Yonekawa, T.; Walimbe, A. S.; Venzke, D. P.; Anderson, M. E.; Hord, J. M.; Campbell, K. P.
10.1101/2023.12.20.572361 — biochemistry — Posted on 2023-12-21
1022 Maximizing glycoproteomics results through an integrated PASEF workflow
Baerenfaenger, M.; Post, M. A.; Zijlstra, F. S. M.; vanGool, A. J.; Wessels, H. J.
10.1101/2023.12.21.570555 — biochemistry — Posted on 2023-12-21
1024 Exploring serial crystallography for drug discovery
Dunge, A.; Phan, C.; Uwangue, O.; Bjelcic, M.; Gunnarsson, J.; Wehlander, G.; Kack, H.; Branden, G.
10.1101/2023.12.21.572778 — biochemistry — Posted on 2023-12-21
1027 A comprehensive map of the ageing blood methylome
Seale, K.; Teschendorff, A.; Reiner, A. P.; Voisin, S.; EYNON, N.
10.1101/2023.12.20.572666 — molecular biology — Posted on 2023-12-21
1031 DNA sensor ABCF1 phase separates with cccDNA to inhibit HBV replication
Ren, C.; Zhang, Z.; Dou, Y.; Sun, Y.; Wang, L.; Fu, Z.; Wang, K.; Gao, C.; Fan, Y.; Sun, S.; Yue, X.; Li, C.; Gao, L.; Liang, X.; Wu, Z.; Ma, C.
10.1101/2023.12.21.572726 — microbiology — Posted on 2023-12-21
1032 Lack of abundant core virome in Culex mosquitoes from a temperate climate region despite a mosquito species-specific virome
De Coninck, L.; Soto, A.; Wang, L.; De Wolf, K.; Smitz, N.; Deblauwe, I.; Mbigha Donfack, K. C.; Muller, R.; Delang, L.; Matthijnssens, J.
10.1101/2023.12.21.572765 — microbiology — Posted on 2023-12-21
1033 Unveiling Cryptosporidium parvum Sporozoite-Derived Extracellular Vesicles: Profiling, Origin, and Protein Composition
Bertuccini, L.; Boussadia, Z.; Salzano, A. M.; Vanni, I.; Passero, I.; Nocita, E.; Scaloni, A.; Sanchez, M.; Sargiacomo, M.; Fiani, M. L.; Tosini, F.
10.1101/2023.12.21.571703 — microbiology — Posted on 2023-12-21
1034 Salt-mediated inactivation of influenza A virus in 1-ul droplets exhibits exponential dependence on NaCl molality
Schaub, A.; Luo, B.; David, S. C.; Glas, I.; Klein, L. K.; Costa, L.; Terrettaz, C.; Bluvshtein, N.; Motos, G.; Violaki, K.; Pohl, M.; Hugentobler, W.; Nenes, A.; Stertz, S.; Krieger, U. K.; Peter, T.; Kohn, T.
10.1101/2023.12.21.572782 — microbiology — Posted on 2023-12-21
1036 Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster
Marking, U.; Bladh, O.; Aguilera, K.; Yang, Y.; Greilert-Norin, N.; Blom, K.; Hober, S.; Klingstrom, J.; Havervall, S.; Aberg, M.; Sheward, D. J.; Thalin, C.
10.1101/2023.12.21.572575 — immunology — Posted on 2023-12-21
1037 Computational detection of antigen specific B cell receptors following immunization
Abbate, M. F.; Dupic, T.; Vigne, E.; Shahsavarian, M. A.; Walczak, A. M.; Mora, T.
10.1101/2023.12.20.572660 — immunology — Posted on 2023-12-21
1038 Powdery mildew effectors AVRA1 and BEC1016 target the ER J-domain protein HvERdj3B required for immunity in barley
Li, Z.; Velasquez-Zapata, V.; Elmore, J. M.; Li, X.; Xie, W.; Deb, S.; Tian, X.; Banerjee, S.; Jorgensen, H. J. L.; Pedersen, C.; Wise, R. P.; Thordal-Christensen, H.
10.1101/2022.04.27.489729 — plant biology — Posted on 2023-12-21
1039 Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2
Panigrahi, A.; Benicky, J.; Aljuhani, R.; Mukherjee, P.; Novakova, Z.; Barinka, C.; Goldman, R.
10.1101/2023.12.20.572603 — cancer biology — Posted on 2023-12-21
1040 Development and validation of allele specific RLK gene markers for banana bunchy top disease (BBTD) resistance in banana
CARO, R. E. S.; Manohar, A. N. C.; Gardoce, R. R.; Dela Cueva, F. M.; Gueco, L. S.; Manuel, M. C. C.; Lantican, D. V.
10.1101/2023.12.20.572701 — genetics — Posted on 2023-12-21
1042 Automated workflow for the cell cycle analysis of non-adherent and adherent cells using a machine learning approach
Hayatigolkhatmi, K.; Soriani, C.; Soda, E.; Ceccacci, E.; El Menna, O.; Peri, S.; Negrelli, I.; Bertolini, G.; Franchi, G. M.; Carbone, R.; Minucci, S.; Rodighiero, S.
10.1101/2023.12.21.572803 — cell biology — Posted on 2023-12-21
1044 Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis
Li, J. J.; Xin, N.; Yang, C.; Tavizon, L. A.; Hong, R.; Moore, T. I.; Tharyan, R. G.; Antebi, A.; Kim, H.-E.
10.1101/2023.09.07.556674 — cell biology — Posted on 2023-12-21
1045 Conformational states of the microtubule nucleator, the γ-tubulin ring complex
Romer, B.; Travis, S. M.; Mahon, B. P.; McManus, C. T.; Jeffrey, P. D.; Coudray, N.; Raghu, R.; Rale, M. J.; Zhong, E. D.; Bhabha, G.; Petry, S.
10.1101/2023.12.19.572162 — molecular biology — Posted on 2023-12-21
1048 Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples From Healthy Individuals
Chappell, C. L.; Hoffman, K. L.; Lorenzi, P. L.; Tan, L.; Petrosino, J.; Gibbs, R.; Muzny, D.; Doddapaneni, H.; Ross, M. C.; Menon, V. K.; Surathu, A.; Javornik Cregeen, S. J.; Reyes, A. G.; Okhuysen, P. C.
10.1101/2023.12.20.572622 — microbiology — Posted on 2023-12-21
1049 Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection
Greenwald, M. A.; Meinig, S. L.; Plott, L. M.; Roca, C.; Higgs, M. G.; Vitko, N. P.; Markovetz, M. R.; Rouillard, K. R.; Carpenter, J.; Kesimer, M.; Hill, D. B.; Schisler, J. C.; Wolfgang, M. C.
10.1101/2023.12.20.572620 — microbiology — Posted on 2023-12-21
1050 Olfactory ensheathing cells are hybrid glial cells that promote neural repair
Phelps, P. E.; Ha, S. M.; Khankan, R. R.; Mekonnen, M. A.; Juarez, G.; Ingraham Dixie, K. L.; Chen, Y.-W.; Yang, X.
10.1101/2023.12.20.572462 — neuroscience — Posted on 2023-12-21
1051 Effects of oscillation phase on discrimination performance in a visual tilt illusion
Williams, J. G.; Harrison, W. J.; Beale, H. A.; Mattingley, J. B.; Harris, A. M.
10.1101/2023.12.20.572703 — neuroscience — Posted on 2023-12-21
1056 Leveraging ancestral sequence reconstruction for protein representation learning
Matthews, D. M.; Spence, M. A.; Mater, A. C.; Nichols, J.; Pulsford, S. B.; Sandhu, M.; Kaczmarski, J. A. B.; Miton, C. M.; Tokuriki, N.; Jackson, C. J.
10.1101/2023.12.20.572683 — bioinformatics — Posted on 2023-12-21
1057 Neural Activity Shaping in Visual Prostheses with Deep Learning
Leite de Castro, D.; Grayden, D. B.; Meffin, H.; Spencer, M. J.
10.1101/2023.12.20.572123 — bioengineering — Posted on 2023-12-21
1059 De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles
An, L.; Said, M.; Tran, L.; Majumder, S.; Goreshnik, I.; Lee, G. R.; Juergens, D.; Dauparas, J.; Anishchenko, I.; Coventry, B.; Bera, A. K.; Kang, A.; Levine, P. M.; Alvarez, V.; Pillai, A.; Norn, C.; Feldman, D.; Zorine, D.; Hicks, D. R.; Li, X.; Sanchez, M. G.; Vafeados, D. K.; Salveson, P. J.; Vorobieva, A. A.; Baker, D.
10.1101/2023.12.20.572602 — biochemistry — Posted on 2023-12-21
1062 Characterization of NEB mutations in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects
Karimi, E.; van der Borgh, M.; Lindqvist, J.; Gohlke, J.; Hourani, Z.; Kolb, J.; Cossette, S.; Lawlor, M.; Ottenheijm, C.; Granzier, H.
10.1101/2023.12.20.572678 — genetics — Posted on 2023-12-21
1066 Converging paths: Harnessing ensemble modelling to predict human wild pig conflict risk zones in Tamil Nadu, India
Shameer, T. T.; Routray, P.; A, U.; Ranjan, N.; Ganesan, M. G.; Manimozhi, A.; Kumari, D. V.
10.1101/2023.12.20.572717 — ecology — Posted on 2023-12-21
1067 Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice
King, A.; Reichl, P.; Metson, J. S.; Parker, R.; Munro, D.; Oliveira, C.; Becker, J. R.; Biggs, D.; Preece, C.; Davies, B.; Chapman, J. R.
10.1101/2023.12.20.572534 — molecular biology — Posted on 2023-12-21
1068 Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
Liu, J. C. Y.; Ackermann, L.; Hoffmann, S.; Gal, Z.; Hendriks, I. A.; Jain, C.; Morlot, L.; Tatham, M. H.; McLelland, G.-L.; Hay, R. T.; Nielsen, M. L.; Brummelkamp, T. R.; Haahr, P.; Mailand, N.
10.1101/2023.12.20.572718 — molecular biology — Posted on 2023-12-21
1070 A community-curated, global atlas of Bacillus cereus sensu lato genomes for epidemiological surveillance
Ramnath, V.; Larralde, M.; Menchik, P.; Buehler, A. J.; Harrand, A. S.; Chung, T.; Wei, X.; Raghuram, V.; Gourle, H.; Pierneef, R.; Matle, I.; Aspholm, M.; Andersson, M.; Cheng, R. A.; Kovac, J.; Henriksson, J.; Carroll, L. M.
10.1101/2023.12.20.572685 — microbiology — Posted on 2023-12-21
1072 CD4+ T cells are homeostatic regulators during Mtb reinfection
Bromley, J.; Ganchua, S. K. C.; Nyquist, S. K.; Maiello, P.; Chao, M.; Borish, H. J.; Rodgers, M.; Tomko, J.; Kracinovsky, K.; Mugahid, D.; Nguyen, S. N.; Wang, D.; Rosenberg, J. M.; Klein, E. C.; Gideon, H. P.; Floyd O Sullivan, R.; Lin, P. L.; Scanga, C.; Fortune, S. M.; Shalek, A. K.; Flynn, J. L.
10.1101/2023.12.20.572669 — immunology — Posted on 2023-12-21
1073 General Anesthesia Activates a Central Anxiolytic Center in the BNST
Lu, D.; Choi, S.; Park, J.; Kim, J.; Zhao, S.; Uldry Lavergne, C. G.; Desimone, Q.; Chen, B.; Han, B.-X.; Wang, F.; Goldstein, N.
10.1101/2023.12.20.572586 — neuroscience — Posted on 2023-12-21
1074 Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice.
Sanchez-Leon, C. A.; Sanchez-Garrido Campos, G.; Fernandez, M.; Sanchez-Lopez, A.; Medina, J. F.; Marquez-Ruiz, J.
10.1101/2023.02.18.529047 — neuroscience — Posted on 2023-12-21
1077 CO-ADMINISTRATION OF RESVERATROL RESCUED LEAD-INDUCED TOXICITY IN DROSOPHILA MELANOGASTER
Abdulazeez, R.; Salisu, M. H.; Onyawole, F. U.; Jeje, M. T.; Musa, H.; Shehu, D. M.; Ndams, I. S.
10.1101/2023.03.09.532003 — pharmacology and toxicology — Posted on 2023-12-21
1078 A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
Grzes, M.; Jaiswar, A.; Grochowski, M.; Wojtys, W.; Kazmierczak, W.; Olesinski, T.; Lenarcik, M.; Nowak-Niezgoda, M.; Kolos, M.; Canarutto, G.; Piazza, S.; Wisniewski, J. R.; Walerych, D.
10.1101/2023.12.20.572548 — cancer biology — Posted on 2023-12-21
1083 Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane
Morel, C.; Lemerle, E.; Tsai, F.-C.; Obadia, T.; Srivastava, N.; Marechal, M.; Salles, A.; Albert, M.; Stefani, C.; Benito, Y.; Vandenesch, F.; Lamaze, C.; Vassilopoulos, S.; Piel, M.; Bassereau, P.; Gonzalez-Rodriguez, D.; Leduc, C.; Lemichez, E.
10.1101/2022.09.27.509635 — biophysics — Posted on 2023-12-21
1087 Physiological constraints limiting the growth of Drosophila larvae
Schönborn, J.; Akhtar, I.; Droste, A.; Wesemann, S.; Beller, M.
10.1101/2023.12.20.572459 — bioinformatics — Posted on 2023-12-21
1091 The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, I.; Vargas-Rosales, P. A.; Bedi, R. K.; Deng, J.; Coelho, D.; Braud, E.; Iannazzo, L.; Li, Y.; Huang, D.; Etheve-Quelquejeu, M.; Cui, Q.; Caflisch, A.
10.1101/2023.09.06.556513 — biochemistry — Posted on 2023-12-21
1095 Nanopore adaptive sampling to identify the NLR-gene family in melon (Cucumis melo L.)
Belinchon-Moreno, J.; Berard, A.; Canaguier, A.; Chovelon, V.; Cruaud, C.; Engelen, S.; Feriche-Linares, R.; Le-Clainche, I.; Lagnel, J.; Marande, W.; Rittener-Ruff, V.; Hinsinger, D.; Boissot, N.; Faivre Rampant, P.
10.1101/2023.12.20.572599 — genomics — Posted on 2023-12-21
1096 Adipose gene expression profiles and their associations with adaptations in Northern Finncattle, Mirandesa cattle, Yakutian cattle and Holstein cattle
Ruvinskiy, D.; Amaral, A.; Weldenegodguad, M.; Honkatukia, M.; Lindeberg, H.; Peippo, J.; Soppela, P.; Stammler, F.; Uimari, P.; Ginja, C.; Kantanen, J.; Pokharel, K.
10.1101/2023.12.21.572790 — genomics — Posted on 2023-12-21
1098 Pangenome comparison of Bacteroides fragilis genomospecies unveil genetic diversity and ecological insights
Oles, R. E.; Carrillo Terrazas, M.; Loomis, L. R.; Hsu, C.-Y.; Tribelhorn, C.; Belda Ferre, P.; Ea, A.; Bryant, M.; Young, J.; Carrow, H. C.; Sandborn, W. J.; Dulai, P.; Sivagnanam, M.; Pride, D. T.; Knight, R.; Chu, H.
10.1101/2023.12.20.572674 — genomics — Posted on 2023-12-21
1099 Assembly and analysis of the genome of Notholithocarpus densiflorus
Cai, Y.; Anderson, E.; Xue, W.; Wong, S.; Cui, L.; Cheng, X.; Wang, O.; Mao, Q.; Liu, S. J.; Davis, J. T.; Magalang, P. R.; Schmidt, D.; Kasuga, T.; Garbelotto, M.; Drmanac, R.; Kua, C.-S.; Cannon, C.; Maloof, J. N.; Peters, B.
10.1101/2023.12.20.572644 — genomics — Posted on 2023-12-21
1101 A validated pangenome-scale metabolic model for the Klebsiella pneumoniae species complex
Cooper, H. B.; Vezina, B.; Hawkey, J.; Passet, V.; Lopez-Fernandez, S.; Monk, J. M.; Brisse, S.; Holt, K. E.; Wyres, K. L.
10.1101/2023.12.20.572682 — genomics — Posted on 2023-12-21
1102 Genomic and Phenotypic Consequences of Bi-Directional Introgression Between Chinese and European Pig Breeds
Qiu, Y.; Liu, L.; Huang, M.; Ruan, D.; Ding, R.; Zhang, Z.; Zheng, E.; Wang, S.; Deng, S.; Cheng, X.; Shi, J.; Yang, Y.; Zhou, F.; Huang, S.; Yang, H.; Li, Z.; Cai, G.; Yang, J.; Wu, Z.
10.1101/2023.12.21.572727 — genetics — Posted on 2023-12-21
1103 Association of poultry vaccination with the interspecies transmission and molecular evolution of H5 subtype avian influenza virus
Li, B.; Raghwani, J.; Hill, S. C.; Francois, S.; Lefrancq, N.; Liang, Y.; Wang, Z.; Dong, L.; Lemey, P.; Pybus, O. G.; Tian, H.
10.1101/2023.12.20.572711 — evolutionary biology — Posted on 2023-12-21
1104 Reduced palatability, fast flight, and tails: Decoding the defence arsenal of Eudaminae skipper butterflies in a Neotropical locality
Linke, D.; Hernandez Mejia, J.; Eche Navarro, V. N. P.; Salinas Sanchez, L.; de Gusmao Ribeiro, P.; Elias, M.; Matos-Maravi, P.
10.1101/2023.12.20.572531 — ecology — Posted on 2023-12-21
1105 Marine transmissible cancer navigates urbanised waters, threatening to spillover
Hammel, M.; Touchard, F.; Burioli, E. A. V.; Paradis, L.; Cerqueira, F.; Chailler, E.; Bernard, I.; Cochet, H.; Simon, A.; Thomas, F.; Destoumieux-Garzon, D.; Charriere, G. M.; Bierne, N.
10.1101/2023.04.14.536605 — ecology — Posted on 2023-12-21
1106 DNA barcoding reveals an increased diversity within the genus Culex (Diptera: Culicidae) in Ireland
Curran, T. G.; O'Hanlon, A.; Gallagher, F.; Pedersen, R. S.; Zintl, A.; Isiye, E.; Olmeda, A. V.; O'Neill, D.; McDevitt, A.; O'Reilly, C.; O'Meara, D. B.
10.1101/2023.12.20.572570 — ecology — Posted on 2023-12-21
1111 Antifungal efficacy of natural antiseptic products against Candida auris
Wu, W.-G.; Luk, K. S.; Hung, M.-F.; Tsang, W.-Y.; Lee, K.-P.; Lam, B. H.-S.; Cheng, K.-L.; Cheung, W.-S.; Tang, H.-L.; To, W.-K.
10.1101/2023.09.22.559057 — microbiology — Posted on 2023-12-21
1112 Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS
Dagva, O.; Thibessard, A.; Lorenzi, J.-N.; Labat, V.; Piotrowski, E.; Rouhier, N.; Myllykallio, H.; Leblond, P.; Bertrand, C.
10.1101/2023.12.20.572499 — microbiology — Posted on 2023-12-21
1114 The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017
Catani, J. P.; Smet, A.; Ysenbaert, T.; Vuylsteke, M.; Bottu, G.; Mathys, J.; Botzki, A.; Cortes-Garcia, G.; Strudnell, T.; Gomila, R.; Hamberger, J.; Catalan, J.; Ustyugova, I.; Farrell, T.; Stegalkina, S.; Ray, S.; LaRue, L.; Saelens, X.; Vogel, T. U.
10.1101/2023.08.30.555500 — immunology — Posted on 2023-12-21
1120 Mind the gap: A systematic review and meta-analysisof how social memory is studied
Cum, M.; Perez, J. S.; Wangia, E.; Lopez, N.; Wright, E. S.; Iwata, R. L.; Li, A.; Chambers, A. R.; Padilla-Coreano, N.
10.1101/2023.12.20.572606 — neuroscience — Posted on 2023-12-21
1121 Arousal as a universal embedding for spatiotemporal brain dynamics
Raut, R. V.; Rosenthal, Z. P.; Wang, X.; Miao, H.; Zhang, Z.; Lee, J.-M.; Raichle, M. E.; Bauer, A. Q.; Brunton, S. L.; Brunton, B. W.; Kutz, J. N.
10.1101/2023.11.06.565918 — neuroscience — Posted on 2023-12-21
1122 Dueling Endogenous Viral-Like Sequences Control Synaptic Plasticity
M'Angale, P. G.; Lemieux, A.; Liu, Y.; Graslie, J.; Wang, S.; Simkin, A.; Budnik, V.; Kelch, B. A.; Thomson, T.
10.1101/2023.12.20.572708 — neuroscience — Posted on 2023-12-21
1123 Auditory cortex encodes lipreading information through spatially distributed activity
Karthik, G.; Cao, C. Z.; Demidenko, M. I.; Jahn, A.; Stacey, W.; Wasade, V. S.; Brang, D.
10.1101/2022.11.11.516209 — neuroscience — Posted on 2023-12-21
1124 Status epilepticus during neurodevelopment increases seizure susceptibility: a model study in zebrafish (Danio rerio)
Mazon, S. C.; Mendes, E. J.; Sachett, A.; Bertoncello, K. T.; Marsaro, I. B.; Daniel, C. F.; Barros de Miranda, F.; Appel Hort, M.; Oliveira, J. V.; Piato, A.; Alves Lima-Rezende, C.; Herrmann, A. P.; Girardi Muller, L.; Siebel, A. M.
10.1101/2023.12.20.572588 — neuroscience — Posted on 2023-12-21
1125 AlphaFold2 structures template ligand discovery
Lyu, J.; Kapolka, N.; Gumpper, R.; Alon, A.; Wang, L.; Jain, M.; Alvarez, X.; Sakamoto, K.; Kim, Y.; DiBerto, J.; Kim, K.; Tummino, T.; Huang, S.; Irwin, J.; Tarkhanova, O.; Moroz, Y.; Skiniotis, G.; Kruse, A.; Shoichet, B.; Roth, B.
10.1101/2023.12.20.572662 — pharmacology and toxicology — Posted on 2023-12-21
1128 Prevalence study of cellular capsid-specific immune responses to AAV1, 2, 4, 5, 8, 9 and rh10 reveals particular features for AAV9
Xicluna, R.; Avenel, A.; Vandamme, C.; Devaux, M.; Jaulin, N.; Couzinie, C.; Le Duff, J.; Charrier, A.; Guilbaud, M.; Adjali, O.; Gernoux, G.
10.1101/2023.12.20.570598 — immunology — Posted on 2023-12-21
1130 Model-Based Closed-Loop Control of Thalamic Deep Brain Stimulation
Tian, Y.; Saradhi, S.; Bello, E.; Johnson, M.; Deleuterio, G.; Popovic, M.; Lankarany, M.
10.1101/2023.12.20.572569 — neuroscience — Posted on 2023-12-21
1132 Transposase-Assisted Tagmentation: An Economical and Scalable Strategy for Single-Worm Whole-Genome Sequencing
Wang, Z.; Ke, J.; Guo, Z.; Wang, Y.; Lei, K.; Wang, S.; Chen, G.; Shen, Z.; Li, W.; Ou, G.
10.1101/2023.12.21.572713 — genomics — Posted on 2023-12-21
1133 Evolution of tissue-specific expression of ancestral genes across vertebrates andinsects
Mantica, F.; Iniguez, L. P.; Marquez, Y.; Permanyer, J.; Torres-Mendez, A.; Cruz, J.; Franch-Marro, X.; Tulenko, F.; Burguera, D.; Bertrand, S.; Doyle, T.; Nouzova, M.; Currie, P.; Noriega, F. G.; Escriva, H.; Arnone, M. I.; Albertin, C. B.; Wotton, K.; Almudi, I.; Martin, D.; Irimia, M.
10.1101/2022.11.14.516384 — genomics — Posted on 2023-12-21
1135 Population Genomics of Postglacial Western Eurasia
Allentoft, M. E.; Sikora, M.; Refoyo-Martinez, A.; Irving-Pease, E. K.; Fischer, A.; Barrie, W.; Ingason, A.; Stenderup, J.; Sjögren, K.-G.; Pearson, A.; Sousa da Mota, B.; Paulsson, B. S.; Halgren, A. S.; Macleod, R.; Schjellerup Jorkov, M. L.; Demeter, F.; Novosolov, M.; Sorensen, L.; Nielsen, P. O.; Henriksen, R. A.; Vimala, T.; McColl, H.; Margaryan, A.; Ilardo, M.; Vaughn, A.; Mortensen, M. F.; Nielsen, A. B.; Hede, M. U.; Rasmussen, P.; Vinner, L.; Renaud, G.; Stern, A. J.; Trolle Jensen, T. Z.; Johannsen, N. N.; Scorrano, G.; Schroeder, H.; Lysdahl, P.; Ramsoe, A.; Skorobogatov, A.; Sc
10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2023-12-21
1139 Group A Streptococcus strains causing meningitis without distinct invasive phenotype
Marquardt, L.; Andreoni, F.; Boumasmoud, M.; Schweizer, T. A.; Heuberger, D.; Parietti, E.; Hertegonne, S.; Epprecht, J.; Mattle, D.; Raez, A.; Marques-Maggio, E.; Schuepbach, R.; Hasse, B. K.; Mairpady Shambat, S.; Brugger, S. D.; Zinkernagel, A.
10.1101/2023.03.22.533757 — microbiology — Posted on 2023-12-21
1140 Machine learning of brain-specific biomarkers from EEG
Bomatter, P.; Paillard, J.; Garces, P.; Hipp, J. F.; Engemann, D. A.
10.1101/2023.12.15.571864 — neuroscience — Posted on 2023-12-21
1142 Single cell transcriptomics reveals chondrocyte differentiation dynamics in vivo and in vitro
Lawrence, J. E. G.; Woods, S.; Roberts, K.; Sumanaweera, D. N.; Balogh, P.; Predeus, A. V.; He, P.; Li, T.; Polanski, K.; Prigmore, E.; Tuck, E.; Mamanova, L.; Zhou, D.; Webb, S.; Jardine, L.; He, X.; Barker, R. A.; Haniffa, M.; Flanagan, A. M.; Young, M. D.; Behjati, S.; Bayraktar, O.; Kimber, S. J.; Teichmann, S.
10.1101/2023.12.20.572425 — bioengineering — Posted on 2023-12-21
1144 Metabolite Fingerprinting for Phenotypic Screening by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry
Joignant, A. N.; Pu, F.; McLoughlin, S. M.; Sawicki, J. W.; Radosevich, A. J.; Ma, R.; Williams, J. D.; Gopalakrishnan, S. M.; Elsen, N. L.
10.1101/2023.12.20.572616 — cell biology — Posted on 2023-12-21
1145 The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity
Carnie, C. J.; Gotz, M. J.; Palma-Chaundler, C. S.; Weickert, P.; Wanders, A. R.; Serrano-Benitez, A.; Li, H.-Y.; Gupta, V.; Blum, C. J.; Sczaniecka-Clift, M.; Zagnoli-Vieira, G.; D'Alessandro, G.; Richards, S. L.; Gueorguieva, N.; Beli, P.; Stingele, J.; Jackson, S. P.
10.1101/2023.12.21.572728 — cell biology — Posted on 2023-12-21
1148 The human Dicer helicase domain mediates ATP hydrolysis and RNA rearrangement
Ciechanowska, K.; Szczepanska, A.; Szpotkowski, K.; Wojcik, K.; Urbanowicz, A.; Kurzynska-Kokorniak, A.
10.1101/2023.06.28.546842 — molecular biology — Posted on 2023-12-21
1149 Electrophysiological Mechanisms in the Anterior Insula Cortex during Reward Expectancy
Yang, L.; Lehongre, K.; Ye, H.; Yu, X.; Navarro, V.; Cheng, S.; Lin, Z.; Axmacher, N.; Wang, S.; Zhang, H.
10.1101/2023.09.19.558205 — neuroscience — Posted on 2023-12-21
1151 Seasonal variation in D2/3 dopamine receptor availability in the human brain
Sun, L.; Malen, T.; Tuisku, J.; Kaasinen, V.; Hietala, J.; Rinne, J.; Nuutila, P.; Nummenmaa, L.
10.1101/2023.12.20.572517 — neuroscience — Posted on 2023-12-21
1153 Egr1 is a sex-specific regulator of neuronal chromatin, synaptic plasticity, and behaviour
Rocks, D.; Purisic, E.; Gallo, E. F.; Greally, J. M.; Suzuki, M.; Kundakovic, M.
10.1101/2023.12.20.572697 — neuroscience — Posted on 2023-12-21
1155 Goal-directed vocal planning in a songbird
Zai, A. T.; Stepien, A. E.; Giret, N.; Hahnloser, R. H. R.
10.1101/2022.09.27.509747 — neuroscience — Posted on 2023-12-21
1156 A subcortical switchboard for exploratory, exploitatory, and disengaged states
Ahmadlou, M.; Yasamin Shirazi, M.; Zhang, P.; Rogers, I. L. M.; Dziubek, J.; Hofer, S. B.
10.1101/2023.12.20.572654 — neuroscience — Posted on 2023-12-21
1157 Modulation of the spatiotemporal dynamics of striatal direct pathway neurons and motor output by mGluR5
Marshall, J. J.; Xu, J.; Yeh, N.-H.; Yun, S.; Nomura, T.; Armstrong, J. N.; Parker, J. G.; Contractor, A.
10.1101/2023.12.20.572676 — neuroscience — Posted on 2023-12-21
1158 Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Menegollo, M.; Bentham, R. B.; Henriques, T.; Ng, S. Q.; Ren, Z.; Esculier, C.; Agarwal, S.; Tong, E.; Ilangovan, S.; Szabadkai, Z.; Suman, M.; Patani, N.; Ghanate, A.; Bryson, K.; Stein, R. C.; Yuneva, M.; Szabadkai, G.
10.1101/2023.02.17.528922 — systems biology — Posted on 2023-12-21
1159 Enhancing gene co-expression network inference for the malaria parasite Plasmodium falciparum
Li, Q.; Button-Simons, K. A.; Sievert, M. A.; Chahoud, E.; Foster, G. F.; Meis, K.; Ferdig, M. T.; Milenkovic, T.
10.1101/2023.05.31.543171 — systems biology — Posted on 2023-12-21
1160 RCPedia: A global resource for studying and exploring retrocopies in diverse species
Conceicao, H. B.; Mercuri, R. L. V.; de Castro, M. P. M.; Ohara, D. T.; Guardia, G. D. A.; Galante, P. A. F.
10.1101/2023.12.20.572530 — bioinformatics — Posted on 2023-12-21
1162 Transcriptomic responses of sponge holobionts to in situ, seasonal anoxia and hypoxia
Strehlow, B. W.; Schuster, A.; Francis, W. R.; Eckford-Soper, L.; Kraft, B.; McAllen, R.; Nielsen, R.; Mandrup, S.; Canfield, D. E.
10.1101/2023.02.27.530229 — ecology — Posted on 2023-12-21
1163 Sorting of secretory proteins at the trans-Golgi network by human TGN46
Lujan, P.; Garcia-Cabau, C.; Wakana, Y.; Vera Lillo, J.; Rodilla-Ramirez, C.; Sugiura, H.; Malhotra, V.; Salvatella, X.; Garcia-Parajo, M. F.; Campelo, F.
10.1101/2022.04.20.488883 — cell biology — Posted on 2023-12-21
1165 Electric field based dosing for TMS
Numssen, O.; Kuhnke, P.; Weise, K.; Hartwigsen, G.
10.1101/2023.07.31.551253 — neuroscience — Posted on 2023-12-21
1167 Surpassing Challenges in Structured-Illumination Microscopy with FlexSIM
Soubies, E.; Nogueron, A.; Pelletier, F.; Mangeat, T.; Leterrier, C.; Unser, M.; Sage, D.
10.1101/2023.12.20.572677 — biophysics — Posted on 2023-12-21
1170 1D confinement mimicking microvessel geometry controls pericyte shape and motility
Sagnimorte, A.; Adler, M. R.; de Tournemire, G.; Saez, P. J.; Gonzalez-Rodriguez, D.; Dessalles, C. A.; Babataheri, A.
10.1101/2023.12.20.572195 — biophysics — Posted on 2023-12-21
1171 Hepatitis B virus neutralization with DNA origami nanoshells
Willner, E.-M.; Kolbe, F.; Momburg, F.; Protzer, U.; Dietz, H.
10.1101/2023.12.20.572526 — biophysics — Posted on 2023-12-21
1174 PD-L1 blockade immunotherapy rewires cancer emergency myelopoiesis
Boumpas, A.; Papaioannou, A. S.; Bousounis, P.; Grigoriou, M.; Bergo, V.; Papafragkos, I.; Tasis, A.; Iskas, M.; Boon, L.; Makridakis, M.; Vlahou, A.; Gavriilaki, E.; Hatzioannou, A.; Mitroulis, I.; Trompouki, E.; Verginis, P.
10.1101/2023.12.20.572561 — immunology — Posted on 2023-12-21
1175 Targeting the Microbiome to Improve Gut Health and Breathing Function After Spinal Cord Injury
Wilson, J. N.; Kigerl, K. A.; Sunshine, M. D.; Taylor, C. E.; Speed, S. L.; Rose, B. C.; Calulot, C. M.; Dong, B. E.; Hawkinson, T. R.; Clarke, H. A.; Bachstetter, A. D.; Waters, C. M.; Sun, R. C.; Popovich, P. G.; Alilain, W. J.
10.1101/2023.06.23.546264 — neuroscience — Posted on 2023-12-21
1179 Assessing the hydromechanical control of plant growth
Laplaud, V.; Demidova, N.; Muller, E.; Drevensek, S.; Boudaoud, A.
10.1101/2023.09.21.558781 — biophysics — Posted on 2023-12-21
1181 Rewriting regulatory DNA to dissect and reprogram gene expression
Martyn, G. E.; Montgomery, M. T.; Jones, H.; Guo, K.; Doughty, B. R.; Linder, J.; Chen, Z.; Cochran, K.; Lawrence, K. A.; Munson, G.; Pampari, A.; Fulco, C. P.; Kelley, D. R.; Lander, E. S.; Kundaje, A.; Engreitz, J. M.
10.1101/2023.12.20.572268 — genetics — Posted on 2023-12-21
1182 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Munugala, C.; Bloom, J. S.; Kruglyak, L.
10.1101/2023.12.07.570640 — genetics — Posted on 2023-12-21
1187 Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control
Vietri Rudan, M.; Sipilä, K.; Philippeos, C.; Ganier, C.; Negri, V. A.; Watt, F. M. M.
10.1101/2023.12.19.572393 — cell biology — Posted on 2023-12-21
1188 SPPiDDRs: a new gene family in dicot plants involved in DNA-Damage Response
Hammoudi, V.; Goldbecker, E.; Herbst, J.; Linnenbrügger, L.; von Schaewen, A.; Kunze, R.
10.1101/2023.12.20.568739 — molecular biology — Posted on 2023-12-21
1189 Regulation of the transcription factor CdnL promotes adaptation to nutrient stress in Caulobacter
Smith, E. L.; Panis, G.; Woldemeskel, S. A.; Viollier, P. H.; Chien, P.; Goley, E. D.
10.1101/2023.12.20.572625 — microbiology — Posted on 2023-12-21
1190 Diverse and Abundant Phages Exploit Conjugative Plasmids
Quinones-Olvera, N.; Owen, S. V.; McCully, L. M.; Marin, M. G.; Rand, E. A.; Fan, A. C.; Dosumu, O. J. M.; Paul, K.; Castano, C. E. S.; Petherbridge, R.; Paull, J. S.; Baym, M.
10.1101/2023.03.19.532758 — microbiology — Posted on 2023-12-21
1191 Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicating
Tanneti, N. S.; Patel, A. K.; Tan, L. H.; Marques, A. D.; Perera, R. A.; Sherrill-Mix, S.; Kelly, B. J.; Collman, R. G.; Rodino, K.; Lee, C.; Bushman, F. D.; Cohen, N. A.; Weiss, S. R.
10.1101/2023.08.24.553565 — microbiology — Posted on 2023-12-21
1193 Opposing diet, microbiome and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host
Vasconcelos Pereira, G.; Boudaud, M.; Wolter, M.; Alexander, C.; De Sciscio, A.; Grant, E.; Caetano Trindade, B.; Singh, S.; Campbell, A.; Pudlo, N.; Willieme, S.; Craig, S.; Kim, K.; Denike-Duval, T.; Kennedy, L.; Schmidt, T.; Chen, G.; Eaton, K.; Desai, M. S.; Martens, E. C.
10.1101/2022.04.03.486886 — microbiology — Posted on 2023-12-21
1194 Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release
Wu, Z.; Kusick, G. F.; Berns, M. M. M.; Raychaudhuri, S.; Itoh, K.; Walter, A. M.; Chapman, E. R.; Watanabe, S.
10.1101/2022.04.21.489101 — neuroscience — Posted on 2023-12-21
1196 Peripheral insulin resistance moderates cerebral glucose metabolism and impairs working memory in healthy younger adults
Deery, H.; Liang, E.; Di Paolo, R. A.; Voigt, K.; Murray, G.; Siddiqui, N.; Moran, C.; Egan, G.; Jamadar, S. D.
10.1101/2023.09.08.556948 — neuroscience — Posted on 2023-12-21
1197 Endangered Przewalski's horse, Equus pzrewalskii, cloned from historically cryopreserved cells
Novak, B. J.; Ryder, O. A.; Houck, M. L.; Putnam, A. S.; Walker, K.; Russell, L.; Russell, B.; Walker, S.; Arenivas, S. S.; Aston, L.; Veneklasen, G.; Ivy, J. A.; Koepfli, K.-P.; Rusnak, A.; Simek, J.; Zhuk, A.; Phelan, R.
10.1101/2023.12.20.572538 — zoology — Posted on 2023-12-21
1201 Low land-use intensity buffers grasslands against future climate and inter-annual climate variability in a large field experiment
Korell, L.; Andrzejak, M.; Berger, S.; Durka, W.; Haider, S.; Hensen, I.; Herion, Y.; Hoefner, J.; Kindermann, L.; Knight, T. M.; Linstaedter, A.; Madaj, A.-M.; Merbach, I.; Michalski, S.; Plos, C.; Roscher, C.; Schaedler, M.; Welk, E.; Auge, H.
10.1101/2023.12.20.572519 — ecology — Posted on 2023-12-21
1203 Age-Related Differences in Human Cortical Microstructure Depend on the Distance to the Nearest Vein
Knoll, C.; Doehler, J.; Northall, A.; Schreiber, S.; Rotta, J.; Mattern, H.; Kuehn, E.
10.1101/2023.12.20.572529 — neuroscience — Posted on 2023-12-21
1205 Single cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions.
Karra, L.; Finger, A.-M.; Shechtman, L.; Krush, M.; Meng-Yao Huang, R.; Prinz, M.; Tennvooren, I.; Bahl, K.; Hysenaj, L.; Gonzalez, P.; combes, a. J.; Gonzalez, H.; Arguello, R.; Spitzer, M.; Roose, J.
10.1101/2023.12.20.572584 — developmental biology — Posted on 2023-12-20
1206 Early transcriptional similarities between two distinct neural lineages during ascidian embryogenesis
Copley, R. R.; Buttin, J.; Arguel, M.-J.; Williaume, G.; Lebrigand, K.; Barbry, P.; Hudson, C.; Yasuo, H.
10.1101/2023.12.20.572557 — developmental biology — Posted on 2023-12-20
1207 PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
He, H.; Bell, S. M.; Davis, A. K.; Zhao, S.; Sridharan, A.; Na, C.-L.; Guo, M.; Xu, Y.; Snowball, J.; Swarr, D. T.; Zacharias, W. J.; Whitsett, J. A.
10.1101/2023.12.20.570481 — developmental biology — Posted on 2023-12-20
1208 ciliR: a new R package for determining ciliary beat frequency using fast-Fourier transformation.
Grant, O.; Larken, I.; Reitemeier, S.; Mitchison, H. M.; Dawes, W.; Phillips, A.; Cortina-Borja, M.; Smith, C. M.
10.1101/2023.12.20.572306 — cell biology — Posted on 2023-12-20
1209 The role of satellite cell-derived TRIM28 in mechanical load- and injury-induced myogenesis
Lin, K.-H.; Hibbert, J. E.; Lemens, J. L.; Torbey, M. M.; Steinert, N. D.; Flejsierowicz, P. M.; Melka, K. M.; Lares, M.; Setaluri, V.; Hornberger, T. A.
10.1101/2023.12.20.572566 — cell biology — Posted on 2023-12-20
1210 THE WIP6 TRANSCRIPTION FACTOR TOO MANY LATERALS SPECIFIES VEIN TYPE IN C4 AND C3 GRASS LEAVES
Vlad, D.; Zaidem, M.; Perico, C.; Sedelnikova, O.; Bhattacharya, S.; Langdale, J. A.
10.1101/2023.12.20.572592 — plant biology — Posted on 2023-12-20
1215 Deep population structure linked to host vernalization requirement in the barley net blotch fungal pathogen
Ramirez Martinez, J.; Guillou, S.; Le Prieur, S.; Di Vittorio, P.; Bonal, F.; Taliadoros, D.; Gueret, E.; Fournier, E.; Stukenbrock, E.; Valade, R.; Gladieux, P.
10.1101/2023.12.20.572564 — evolutionary biology — Posted on 2023-12-20
1216 Deep profiling of antigen-specific B cells from different pathogens identifies novel compartments in the IgG memory B cell and antibody-secreting cell lineages
Claireaux, M.; Elias, G.; Kerster, G.; Kuijper, L. H.; Duurland, M. C.; Paul, A. G.; Burger, J. A.; Poniman, M.; Olijhoek, W.; de Jong, N.; de Jongh, R.; Wynberg, E.; van Willigen, H. D.; Prins, M.; de Bree, G. J.; de Jong, M. D.; Kuijpers, T. W.; Eftimov, F.; van der Schoot, C. E.; Rispens, T.; Garcia-Vallejo, J. J.; ten Brinke, A.; van Gils, M. J.; van Ham, S. M.
10.1101/2023.12.19.572339 — immunology — Posted on 2023-12-20
1217 Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19
Lee, J. T. H.; Barnett, S. N.; Roberts, K.; Ashwin, H.; Milross, L.; Cho, J.-W.; Huseynov, A.; Woodhams, B.; Aivazidis, A.; Li, T.; Majo, J.; Guerrero, P. C.; Lee, M.; Miranda, A. M. A.; Jablonska, Z.; Arena, V.; Hanley, B.; Osborn, M.; Uhlmann, V.; Xu, X.-N.; McLean, G. R.; Teichmann, S. A.; Randi, A. M.; Filby, A.; Kaye, P. M.; Fisher, A. J.; Hemberg, M.; Noseda, M.; Bayraktar, O. A.
10.1101/2023.12.20.572494 — pathology — Posted on 2023-12-20
1219 BioLLMBench: A Comprehensive Benchmarking of Large Language Models in Bioinformatics
Sarwal, V.; Munteanu, V.; Suhodolschi, T.; Ciorba, D.; Eskin, E.; Wang, W.; Mangul, S.
10.1101/2023.12.19.572483 — bioinformatics — Posted on 2023-12-20
1221 MUT-7 exoribonuclease activity and localisation are mediated by an ancient domain
Busetto, V.; Pshanichnaya, L.; Lichtenberger, R.; Hann, S.; Ketting, R. F.; Falk, S.
10.1101/2023.12.20.572533 — biochemistry — Posted on 2023-12-20
1225 Addressing heterogeneity in direct analysis of Extracellular Vesicles and analogues using Membrane-Sensing Peptides as Pan-Affinity Probes
Gori, A.; Frigerio, R.; Gagni, P.; Burrello, J.; Panella, S.; Raimondi, A.; Bergamaschi, G.; Lodigiani, G.; Romano, M.; Zendrini, A.; Radeghieri, A.; Barile, L.; Cretich, M.
10.1101/2023.12.20.572525 — biochemistry — Posted on 2023-12-20
1226 Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells
Li, Z.; Di Vagno, L.; Ni Cheallaigh, A.; Sammon, D.; Briggs, D. C.; Chung, N.; Chang, V.; Mahoney, K. E.; Cioce, A.; Murphy, L. D.; Chen, Y.-H.; Narimatsu, Y.; Miller, R. L.; Willems, L. I.; Malaker, S. A.; Miller, G. J.; Hohenester, E.; Schumann, B.
10.1101/2023.12.20.572522 — biochemistry — Posted on 2023-12-20
1227 L-glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and signaling
Forbes, M.; Kempa, R.; Mastrobuoni, G.; Rayman, L.; Pietzke, M.; Bayram, S.; Arlt, B.; Spruessel, A.; Deubzer, H.; Kempa, S.
10.1101/2023.12.20.572547 — biochemistry — Posted on 2023-12-20
1229 Mitochondrial morphology and function in mitochondrial disease
Faitg, J.; Davey, T.; Laws, R.; Lawless, C.; Tuppen, H.; Fitton, E.; Turnbull, D. E.; Vincent, A. E.
10.1101/2023.12.20.571319 — molecular biology — Posted on 2023-12-20
1230 Methylation Array Signals are Predictive of Chronological Age Without Bisulfite Conversion
Porter, H. L.; Ansere, V. A.; Undi, R. B.; Hoolehan, W.; Giles, C. B.; Brown, C. A.; Stanford, D.; Huycke, M. M.; Freeman, W. M.; Wren, J. D.
10.1101/2023.12.20.572465 — molecular biology — Posted on 2023-12-20
1231 Cell type-specific adaptation of the SARS-CoV-2 spike
Carrascosa-Saez, M.; Marques, M.-C.; The IBV-COVID19-Pipeline, ; Geller, R.; Elena, S. F.; Rahmeh, A.; Dufloo, J.; Sanjuan, R.
10.1101/2023.12.20.572504 — microbiology — Posted on 2023-12-20
1233 The developing pig respiratory microbiome harbours strains antagonistic to common respiratory pathogens
Vlasblom, A. A.; Duim, B.; Patel, S.; Luiken, R.; Crespo-Piazuelo, D.; Eckenberger, J.; Huseyin, C. E.; Lawlor, P. G.; Elend, C.; Wagenaar, J. A.; Claesson, M. J.; Zomer, A. L.
10.1101/2023.12.20.572551 — microbiology — Posted on 2023-12-20
1235 Sculpting conducting nanopore size and shape through de novo protein design
Berhanu, S.; Majumder, S.; Muntener, T.; Whitehouse, J.; Berner, C.; Bera, A. K.; Kang, A.; Liang, B.; Khan, G. N.; Sankaran, B.; Tamm, L.; Brockwel, D. J.; Hiller, S.; Radford, S.; Baker, D.; Vorobieva, A. A.
10.1101/2023.12.20.572500 — synthetic biology — Posted on 2023-12-20
1240 Gut microbiota influences foraging onset without affecting division of labor and associated physiological hallmarks in honeybees
Liberti, J.; Frank, E. T.; Kay, T.; Kesner, L.; Monie-Ibanes, M.; Quinn, A.; Schmitt, T.; Keller, L.; Engel, P.
10.1101/2023.12.20.570781 — evolutionary biology — Posted on 2023-12-20
1241 Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects
Ghose, R.; Pezzano, F.; Kourtis, S.; Sheraj, I.; Das, S.; Ganez-Zapater, A.; Ghose, U.; Espinar, L.; Parapatics, K.; Venturini, V.; Muller, A. C.; Ruprecht, V.; Sdelci, S.
10.1101/2023.12.20.572417 — cell biology — Posted on 2023-12-20
1242 WITHDRAWN: Atlas of Fshr Expression from Novel Reporter Mice
Chen, H.-Q.; Fang, H.; Liu, J.-T.; Chang, S.-Y.; Cheng, L.-B.; Sun, M.-X.; Feng, J.-R.; Liu, Z.; Zhang, Y.; Zaidi, M.; J. Rosen, C.; Liu, P.
10.1101/2023.11.05.565707 — cell biology — Posted on 2023-12-20
1243 P-NADs: PUX-based NAnobody Degraders for Ubiquitin-Independent Degradation of Target Proteins
Wang, J.; Chistov, G.; Zhang, J.; Huntington, B.; Salem, I.; Sandholu, A.; Arold, S. T.
10.1101/2023.12.20.572486 — synthetic biology — Posted on 2023-12-20
1244 YAP1 status defines two intrinsic subtypes of LCNEC with distinct molecular features and therapeutic vulnerabilities
Stewart, C. A.; Diao, L.; Xi, Y.; Wang, R.; Ramkumar, K.; Serrano, A. G.; Rodriguez, B. L.; Morris, B. B.; Shen, L.; Zhang, B.; Yang, Y.; Hamad, S. H.; Cardnell, R. J.; Duarte, A.; Sahu, M.; Novegil, V. Y.; Weissman, B. E.; Frumovitz, M.; Kalhor, N.; Soto, L. S.; da Rocha, P. S.; Vokes, N.; Gibbons, D. L.; Wang, J.; Heymach, J.; Glisson, B.; Byers, L. A.; Gay, C. M.
10.1101/2023.12.19.572449 — cancer biology — Posted on 2023-12-20
1247 High CD44 expression identifies rare chemoresistant leukemic cells endowed with enhanced E-Selectin binding in T-ALL
Calvo, J.; Naguibneva, I.; Kypraios, A.; Uzan, B.; Gaillard, B.; Bellenger, L.; Renou, L.; Antoniewski, C.; Lapillone, H.; Petit, A.; Ballerini, P.; Mancini, S. J.; Marchand, T.; Peyron, J.-F.; Pflumio, F.
10.1101/2023.12.20.572048 — cancer biology — Posted on 2023-12-20
1248 RAPID RESISTANCE TO BET INHIBITORS IS MEDIATED BY FGFR1 IN GLIOBLASTOMA
Jermakowicz, A. M.; Kurimchak, A. M.; Johnson, K. J.; Bourgain-Guglielmetti, F.; Kaeppeli, S.; Affer, M.; Pradhyumnan, H.; Suter, R.; Walters, W.; Cepero, M.; Duncan, J.; Ayad, N. G.
10.1101/2023.12.19.572401 — cancer biology — Posted on 2023-12-20
1249 Inactivation of p53 drives breast cancer brain metastasis by altering fatty acid metabolism
Laue, K.; Pozzi, S.; Cohen-Sharir, Y.; Winkler, T.; Eliezer, Y.; Israeli Dangoor, S.; Leikin-Frenkel, A.; Lange, K.; Zerbib, J.; Ricci, A. A.; Sacconi, A.; Berthelet, J.; Schaffer, A.; Shi, W.; Liao, Y.; Barshack, I.; Medyouf, H.; Merino, D.; Blandino, G.; Bertero, L.; Satchi-Fainaro, R.; Ben-David, U.
10.1101/2023.12.20.572490 — cancer biology — Posted on 2023-12-20
1254 Matrix Linear Models for connecting metabolite composition to individual characteristics
Farage, G.; Zhao, C.; Choi, H. Y.; Garrett, T. J.; Kechris, K.; Elam, M. B.; Sen, S.
10.1101/2023.12.19.572450 — bioinformatics — Posted on 2023-12-20
1258 Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion
Lapuente-Santana, O.; Sturm, G.; Kant, J.; Ausserhofer, M.; Zackl, C.; Zopoglou, M.; McGranahan, N.; Rieder, D.; Trajanoski, Z.; de Miranda, N. F. d. C. C.; Eduati, F.; Finotello, F.
10.1101/2023.12.20.572033 — bioinformatics — Posted on 2023-12-20
1263 Structural elucidation of how ARF small GTPases induce membrane tubulation for vesicle fission
Pang, X.; Zhang, Y.; Park, K.; Liao, Z.; Li, J.; Xu, J.; Hong, M.-T.; Yin, G.; Zhang, T.; Wang, Y.; Egelman, E. H.; Fan, J.; Park, S.-Y.; Hsu, V. W.; Sun, F.
10.1101/2023.12.19.572083 — cell biology — Posted on 2023-12-20
1264 Chemical genetic interaction linking eIF5A hypusination and mitochondrial integrity
Matsumoto, K.; Kurokawa, R.; Takase, M.; Schneider-Poetsch, T.; Ling, F.; Suzuki, T.; Han, P.; Wakigawa, T.; Suzuki, M.; Tariq, M.; Ito, A.; Higashi, K.; Iwasaki, S.; Dohmae, N.; Yoshida, M.
10.1101/2023.12.20.571781 — cell biology — Posted on 2023-12-20
1266 Chlamydial protease-like activating factor targets SLC7A11 for degradation to induce ferroptosis and facilitate dissemination.
Chen, W.; Su, X.; Pan, Y.; Xue, Y.; Zeng, L.; Xu, Q.; Yu, X.; Yin, X.; Zhou, H.; Feng, Z.; Zhang, B.; Zhao, W.; Zheng, H.
10.1101/2023.12.20.572489 — microbiology — Posted on 2023-12-20
1268 CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation epigenetically and inflammatory signaling through a short, encoded peptide
Halasz, H.; Malekos, E.; Covarrubias, S.; Yitiz, S.; Montano, C.; Sudek, L.; Katzman, S.; Liu, S. J.; Horlbeck, M. A.; Weissman, J. S.; Carpenter, S.
10.1101/2023.12.19.572453 — immunology — Posted on 2023-12-20
1271 Human disease-specific cell signatures in non-lesional tissue in Multiple Sclerosis detected by single-cell and spatial transcriptomics
Lam, M.; Lee, D.; Kosater, I.; Khairallah, A.; Taga, M.; Zhang, Y.; Fujita, M.; Nag, S.; Bennett, D. A.; De Jager, P.; Menon, V.
10.1101/2023.12.20.572491 — neuroscience — Posted on 2023-12-20
1273 High-speed AFM reveals fluctuations and dimer splitting of the N-terminal domain of GluA2-γ2
Sumino, A.; Sumikama, T.; Zhao, Y.; Flechsig, H.; Umeda, K.; Kodera, N.; Hattori, M.; Shibata, M.
10.1101/2023.12.19.572481 — neuroscience — Posted on 2023-12-20
1278 Plant metabolites modulate animal social networks and lifespan
SINGH, P.; Brueggemann, L.; Janz, S.; Saidi, Y.; Baruah, G.; Müller, C.
10.1101/2023.12.20.572488 — animal behavior and cognition — Posted on 2023-12-20
1283 Elasto-Plastic Transition in Epithelial Folding
Teranishi, A.; Mori, M.; Ichiki, R.; Toda, S.; Shioi, G.; Okuda, S.
10.1101/2023.12.19.572470 — developmental biology — Posted on 2023-12-20
1285 Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure
Moshkelgosha, S.; Levy, L.; Safavi, S.; Karunagaran, S.; Wilson, G.; Renaud-Picard, B.; Madu, G.; Ramchandani, R.; Oliver, J.; Watanabe, T.; Bei, K. F.; Joe, B.; Li, Q.; Huszti, E.; Cheung, M.; Hedley, D.; Yeung, J.; Keshavjee, S.; Martinu, T.; Juvet, S.
10.1101/2023.12.19.572416 — immunology — Posted on 2023-12-20
1296 Using a decision tree to predict COVID case numbers: a tutorial for beginners
Moctezuma Tan, L.; Benitez, L.; van Nouhuijs, F.; Orcales, F.; Kim, A.; Campbell, R.; Fuse, M.; Pennings, P. S.
10.1101/2023.12.19.572463 — scientific communication and education — Posted on 2023-12-20
1298 Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) root
Drapal, M.; Becerra Lopez-Lavalle, L. A.; Fraser, P. D.; Ovalle Rivera, T. M.
10.1101/2023.12.19.572370 — plant biology — Posted on 2023-12-20
1301 In vivo binding free energy landscape reveals kinetic control of transcription factor function
Huynh, D.; Hoffmeister, P.; Friedrich, T.; Zhang, K.; Bartkuhn, M.; Ferrante, F.; Giaimo, B. D.; Kovall, R.; Borggrefe, T.; Oswald, F.; Gebhardt, J. C. M.
10.1101/2023.12.19.572376 — biophysics — Posted on 2023-12-20
1302 Homology detection using a protein secondary structure-based large language model
Kogay, R.; Ma, W.; Bousselham, J.; Yang, Z.; Rockmore, D.; Zhaxybayeva, O.; Vosoughi, S.
10.1101/2023.12.19.572443 — bioinformatics — Posted on 2023-12-20
1303 FAIR Header Reference genome: A TRUSTworthy standard
Wright, A.; Wilkinson, M. D.; Mungall, C.; Cain, S.; Richards, S.; Sternberg, P.; Provin, E.; Jacobs, J. L.; Geib, S.; Raciti, D.; Yook, K.; Stein, L.; Molik, D. C.
10.1101/2023.11.29.569306 — bioinformatics — Posted on 2023-12-20
1304 FastProtein: An automated software for in silico proteomic analysis
Moreira, R. S.; Filho, V. B.; Maia, G. A.; Soratto, T. A. T.; Kawagoe, E. K.; Russi, B. C.; Miletti, L. C.; Wagner, G.
10.1101/2023.12.19.572382 — bioinformatics — Posted on 2023-12-20
1306 Electroadhesive hydrogel interface for prolonged mucosal theranostics
Ying, B.; Nan, K.; Zhu, Q.; Khuu, T.; Ro, H.; Qin, S.; Wang, S.; Jiang, K.; Chen, Y.; Bao, G.; Jenkins, J.; Pettinari, A.; Kuosmanen, J.; Ishida, K.; Lopez, A.; Li, J.; Hayward, A.; Langer, R.; Traverso, G.
10.1101/2023.12.19.572448 — bioengineering — Posted on 2023-12-20
1307 Structural basis for human mitochondrial tRNA maturation
Meynier, V.; Hardwick, S. W.; Catala, M.; Roske, J.; Oerum, S.; Chirgadze, D. Y.; Barraud, P.; Yue, W.; Luisi, B.; Tisne, C.
10.1101/2023.12.19.572246 — biochemistry — Posted on 2023-12-20
1309 Conformational states of the microtubule nucleator, the γ-tubulin ring complex
Romer, B.; Travis, S. M.; Mahon, B. P.; McManus, C. M.; Jeffrey, P. D.; Coudray, N.; Raghu, R.; Rale, M. J.; Zhong, E. D.; Bhabha, G.; Petry, S.
10.1101/2023.12.19.572162 — molecular biology — Posted on 2023-12-20
1312 Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans
Castro, P.; Luppi, A.; Tagliazucchi, E.; Sanz Perl, Y.; Naci, L.; Owen, A. M.; Sitt, J.; Destexhe, A.; Cofre, R.
10.1101/2023.12.19.572402 — neuroscience — Posted on 2023-12-20
1313 SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus
Wu, D.; Yang, C.; Yao, Y.; Ma, D.; Lin, H.; Hao, L.; Xin, W.; Ye, K.; Sun, M.; Hu, Y.; Yang, Y.; Zhuang, Z.
10.1101/2023.12.19.572357 — pharmacology and toxicology — Posted on 2023-12-20
1314 Evolution of resistance to KRASG12C inhibitor in a non-small cell lung cancer responder
Xu, J.; Wang, S.; Wang, Z.; Huang, J.; Xie, C.; Cao, Y.; Ming, C.; Leung, E. L.-H.
10.1101/2023.12.18.572090 — cancer biology — Posted on 2023-12-20
1315 The YARS Tyrosyl tRNA Synthetase Regulates Senescence Induction and Escape Through the Transcriptional Control of LIN9, a Member of the DREAM Complex
Coquelet, H.; Leman, G.; Maarouf, A.; Petit, C.; Toutain, B.; Henry, C.; Boissard, A.; Guette, C.; Lelievre, E.; Vidi, P.; Guillon, J.; Coqueret, O.
10.1101/2023.12.19.571263 — cancer biology — Posted on 2023-12-20
1316 A rise in double-strand breaks sensitizes tumours to oxidative metabolism inhibitors
Medina-Jover, F.; Figueras, A.; Lahiguera, A.; Guillen, P.; Espin, R.; Pardo, M. A.; Pujana, M. A.; Berra, E.; Villanueva, A.; Bernat, A.; Romeo, M.; Perales, J. C.; Vinals, F.
10.1101/2023.12.19.572355 — cancer biology — Posted on 2023-12-20
1317 Stress-induced Rab11a-exosomes induce AREG-mediated cetuximab resistance in colorectal cancer
Mason, J. D.; Marks, E.; Fan, S.-J.; McCormick, K.; Wilson, C.; Harris, A. L.; Hamdy, F. C.; Cunningham, C.; Goberdhan, D. C. I.
10.1101/2023.12.19.572341 — cancer biology — Posted on 2023-12-20
1318 Neratinib Synergizes with Trastuzumab Antibody Drug Conjugate or with Vinorelbine to Treat HER2 Mutated Breast Cancer Patient Derived Xenografts and Organoids.
Li, S.; Primeau, T. M.; Highkin, M. K.; Pratt, S. L.; Tipton, A. R.; Vemalapally, N.; Monsey, J. D.; Tao, Y.; Luo, J.; Hagemann, I. S.; Lin, C.-Y.; Eli, L. D.; Ma, C. X.; Bose, R.
10.1101/2023.12.19.572069 — cancer biology — Posted on 2023-12-20
1321 Drug Repositioning using Consilience of Knowledge Graph Completion Methods
Tu, R.; Sinha, M.; Gonzalez-Cavazos, A. C.; Hu, E.; Dhuliawala, S. Z.; McCallum, A.; Su, A. I.
10.1101/2023.05.12.540594 — bioinformatics — Posted on 2023-12-20
1322 Senolytics enhance longevity in Caenorhabditis elegans by altering betaine metabolism
Lan, W.; Xiao, X.; Zhang, X.; Nian, J.; Wang, Z.; Wu, Y.; Zhang, D.; Chen, J.; Bao, W.; Li, C.; Zhu, A.; Zhang, Y.; Zhang, F.
10.1101/2023.12.19.572398 — biochemistry — Posted on 2023-12-20
1325 Stage-sensitive potential of isolated rabbit ICM to differentiate into extraembryonic lineages
Filimonow, K.; Choloniewska, A.; Choloniewski, J.; Madeja, Z. E.; Barlowska, K.; Grabarek, J.; Plusa, B.; Piliszek, A.
10.1101/2023.12.19.571672 — developmental biology — Posted on 2023-12-20
1329 Distribution and Triazole Susceptibility of Aspergilli from Clinical, Soils and Veterinary Samples in Ogun State, Nigeria.
Olugbenga, B. O. M.; Easter, T.; Shittu, O. B.; Obuotor, T. M.; Sam-Wobo, S. O.; Ejilude, O.; van Rhijn, N.
10.1101/2023.12.19.572319 — microbiology — Posted on 2023-12-20
1332 Neural Interoceptive Processing is Modulated by Deep Brain Stimulation for Treatment Resistant Depression
Xu, E.; Pitts, S.; Dahill-Fuchel, J. F.; Scherrer, S.; Nauvel, T.; Overton, J. A.; Riva-Posse, P.; Crowell, A.; Figee, M.; Alagapan, S.; Rozell, C.; Choi, K. S.; Mayberg, H. S.; Waters, A. C.
10.1101/2023.12.15.571885 — neuroscience — Posted on 2023-12-20
1333 Visual imagery vividness correlates with afterimage brightness and sharpness
Kronemer, S. I.; Holness, M.; Morgan, A. T.; Teves, J. B.; Gonzalez-Castillo, J.; Handwerker, D. A.; Bandettini, P. A.
10.1101/2023.12.07.570716 — neuroscience — Posted on 2023-12-20
1334 Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain
Peach, C. J.; Tonello, R.; Gomez, K.; Calderon-Rivera, A.; Rodriguez Sanchez, M.; Maile, L.; Perez-Miller, S.; Manu, A.-M.; Hahn, H.; Thomsen, A. R. B.; Schmidt, B. L.; Davidson, S.; Khanna, M.; Khanna, R.; Bunnett, N. W.
10.1101/2023.12.06.570398 — neuroscience — Posted on 2023-12-20
1336 Dopamine-iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
Buoso, C.; Seifert, M.; Lang, M.; Griffith, C. M.; Andujar, B. T.; Rueda, M. P. C.; Fischer, C.; Doerrier, C.; Talasz, H.; Zanon, A.; Pramstaller, P. P.; Schymanski, E. L.; Pichler, I.; Weiss, G.
10.1101/2023.12.19.572356 — neuroscience — Posted on 2023-12-20
1337 Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance and resetting in winter wheat
Liu, X.; Lin, X.; Deng, M.; Shi, B.; Chen, J.; Li, H.; Xu, S.; Bie, X.; Zhang, X.; Chong, K.; Xiao, J.
10.1101/2023.12.19.572364 — plant biology — Posted on 2023-12-20
1341 Neural Trajectories of Conceptually Related Events
Schafer, M.; Kamilar-Britt, P.; Sahani, V.; Bachi, K.; Schiller, D.
10.1101/2023.12.04.569670 — neuroscience — Posted on 2023-12-20
1342 Machine learning of brain-specific biomarkers from EEG
Bomatter, P.; Paillard, J.; Garces, P.; Hipp, J. F.; Engemann, D. A.
10.1101/2023.12.15.571864 — neuroscience — Posted on 2023-12-20
1343 Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia
Zhu, B.; Ainsworth, R. I.; Wang, Z.; Liu, Z.; Sierra, S.; Deng, C.; Callado, L. F.; Meana, J. J.; Wang, W.; Lu, C.; Gonzalez-Maeso, J.
10.1101/2021.07.14.452426 — neuroscience — Posted on 2023-12-20
1344 Tools and methods for high-throughput single-cell imaging with the mother machine
Thiermann, R.; Sandler, M.; Ahir, G.; Sauls, J. T.; Schroeder, J. W.; Brown, S. D.; Le Treut, G.; Si, F.; Li, D.; Wang, J.; Jun, S.
10.1101/2023.03.27.534286 — systems biology — Posted on 2023-12-20
1345 A scenario for an evolutionary selection of ageing
Roget, T.; Macmurray, C.; Jolivet, P.; Meleard, S.; Rera, M.
10.1101/2022.03.11.483978 — evolutionary biology — Posted on 2023-12-20
1346 TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning
de Calbiac, H.; Montealegre, S.; Straube, M.; Renault, S.; Debruge, H.; Chentout, L.; Ciura, S.; Imbard, A.; Le Guillou, E.; Marian, A.; Goudin, N.; Caccavelli, L.; Fabrega, S.; Hubas, A.; van Endert, P.; Dupont, N.; Diana, J.; Kabashi, E.; de Lonlay, P.
10.1101/2023.03.29.534583 — cell biology — Posted on 2023-12-20
1347 Prevotella copri-related effects of a therapeutic food for malnutrition
Chang, H.-W.; Lee, E. M.; Wang, Y.; Zhou, C.; Pruss, K. M.; Henrissat, S.; Chen, R. Y.; Kao, C.; Hibberd, M. C.; Lynn, H. M.; Webber, D. M.; Crane, M.; Cheng, J.; Rodionov, D. A.; Arzamasov, A. A.; Castillo, J. J.; Couture, G.; Chen, Y.; Balcazo, N. P.; Lebrilla, C. B.; Terrapon, N.; Henrissat, B.; Ilkayeva, O.; Muehlbauer, M. J.; Newgard, C.; Mostafa, I.; Das, S.; Mahfuz, M.; Osterman, A.; Barratt, M. J.; Ahmed, T.; Gordon, J.
10.1101/2023.08.11.553030 — microbiology — Posted on 2023-12-20
1348 Representation and quantification Of Module Activity from omics data with rROMA
Najm, M.; Cornet, M.; Albergante, L.; Zinovyev, A.; Sermet-Gaudelus, I.; Stoven, V.; Calzone, L.; Martignetti, L.
10.1101/2022.10.24.513448 — systems biology — Posted on 2023-12-20
1349 A Mechanistic Model for the Release of Ceramide from the CERT START Domain
Moqadam, M.; Gartan, P.; Talandashti, R.; Chiapparino, A.; Titeca, K.; Gavin, A.-C.; Reuter, N.
10.1101/2023.12.16.571968 — biophysics — Posted on 2023-12-20
1352 Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro, V.; Bertol, J.; Gutierrez, C.; Palacios, A.; Pasquina-Lemonche, L.; Espalliat, A.; Lerma, L.; Weinrick, B.; Lavin, J. L.; Elortza, F.; Azkalgorta, M.; Prieto, A.; Buendia-Nacarino, P.; Luque-Garcia, J. L.; Neyrolles, O.; Cava, F.; Hobbs, J.; Sanz, J.; Prados-Rosales, R.
10.1101/2023.11.19.567727 — microbiology — Posted on 2023-12-20
1354 Characterizing Molecular and Synaptic Signatures in Mouse Models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology
Kotredes, K. P.; PANDEY, R. S.; Persohn, S. C.; Eldridge, K.; Burton, C. P.; Miner, E. W.; Haynes, K. A.; Santos, D. F. S.; Williams, S.-P.; Heaton, N.; Ingraham, C.; Lloyd, C.; Garceau, D.; O'Rourke, R.; Herrick, S.; Rangel-Barajas, C. L.; Maharjan, S. L.; Wang, N. L.; Sasner, M. J.; Lamb, B. T.; Territo, P. R.; Rizzo, S. J. S.; Carter, G. W.; Howell, G.; Oblak, A.
10.1101/2023.12.19.571985 — neuroscience — Posted on 2023-12-20
1358 OneFlowTraX: A User-Friendly Software for Super-Resolution Analysis of Single-Molecule Dynamics and Nanoscale Organization
Rohr, L.; Ehinger, A.; Rausch, L.; Burmeister, N. G.; Meixner, A. J.; Gronnier, J.; Harter, K.; Kemmerling, B.; zur Oven-Krockhaus, S.
10.1101/2023.08.10.552827 — plant biology — Posted on 2023-12-20
1360 Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
Tissink, E.; Shadrin, A. A.; van der Meer, D.; Parker, N.; Hindley, G.; Roelfs, D.; Frei, O.; Fan, C. C.; Nagel, M.; Naerland, T.; Budisteanu, M.; Djurovic, S.; Westlye, L. T.; van den Heuvel, M.; Posthuma, D.; Kaufmann, T.; Dale, A. M.; Andreassen, O.
10.1101/2022.12.20.521181 — genetics — Posted on 2023-12-20
1362 pyRBDome: A comprehensive computational platform for enhancing and interpreting RNA-binding proteome data
Chu, L.-C.; Christopoulou, N.; McCaughan, H.; Winterbourne, S.; Cazzola, D.; Wang, S.; Litvin, U.; Brunon, S.; Harker, P. J. B.; McNae, I.; Granneman, S.
10.1101/2023.12.08.570608 — systems biology — Posted on 2023-12-20
1363 An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat
Behm, M.; Baeza-Centurion, P.; Busa, V. F.; Penso-Dolfin, L.; Botey, F. J.; Delaunay, S.; Hirschmuller, N.; Koch, M.-L.; Del Prete, S.; Sohn, D.; Reifenberg, C.; Schopp, M.; Lammers, F.; Sole-Boldo, L.; Dutton, J.; Wagner, R. E.; Blanco, S.; Begall, S.; Khaled, W.; Smith, E. S. J.; Odom, D. T.; Frye, M.; Goncalves, A.
10.1101/2023.10.10.561212 — cancer biology — Posted on 2023-12-20
1367 A bipolar taxonomy of adult human brain sulcal morphology related to timing of fetalsulcation and trans-sulcal gene expression gradients
Snyder, W. E.; Vertes, P. E.; Kyriakopoulou, V.; Wagstyl, K.; Williams, L. Z. J.; Moraczewski, D.; Thomas, A. G.; Karolis, V. R.; Seidlitz, J. R.; Riviere, D.; Robinson, E. C.; Mangin, J.-F.; Raznahan, A.; Bullmore, E. T.
10.1101/2023.12.19.572454 — neuroscience — Posted on 2023-12-20
1369 Higher-order thalamocortical projections selectively control excitability via NMDAR and mGluRI-mediated mechanisms.
Brandalise, F.; Chereau, R.; Morin Raig, C.; Bawa, T.; Mule, N.; Pages, S.; Markopoulos, F.; Holtmaat, A.
10.1101/2023.12.20.572353 — neuroscience — Posted on 2023-12-20
1371 Differences in sperm swimming speed and morphology between the three genetic morphs in the ruff sandpiper
Bulla, M.; Küpper, C.; Lank, D. B.; Albrechtova, J.; Loveland, J. L.; Martin, K.; Teltscher, K.; Cragnolini, M.; Lierz, M.; Albrecht, T.; Forstmeier, W.; Kempenaers, B.
10.1101/2023.07.27.550846 — evolutionary biology — Posted on 2023-12-20
1372 Non-canonical contribution of human Dicer helicase domain in antiviral innate immune response
Baldaccini, M.; Gaucherand, L.; Chane-Woon-Ming, B.; Messmer, M.; Gucciardi, F.; Pfeffer, S.
10.1101/2023.08.23.554407 — molecular biology — Posted on 2023-12-20
1373 TurboID mapping reveals exportome of secreted intrinsically disordered proteins in the transforming parasite Theileria annulata
Bruhlmann, F.; Perry, C.; Gunasekera, K.; Reymond, J.-L.; Naguleswaran, A.; Rottenberg, S.; Woods, K.; Olias, P.
10.1101/2023.12.14.571664 — microbiology — Posted on 2023-12-20
1379 A Bayesian active learning platform for scalable combination drug screens
Tosh, C.; Tec, M.; White, J.; Quinn, J. F.; Ibanez Sanchez, G.; Calder, P.; Kung, A. L.; Dela Cruz, F. S.; Tansey, W.
10.1101/2023.12.18.572245 — bioinformatics — Posted on 2023-12-20
1381 Human neuron subtype programming through combinatorial patterning with scRNA-seq readouts
Lin, H.-C.; Janssens, J.; Kroell, A.-S.; Hornauer, P.; Santel, M.; Okamoto, R.; Karava, K.; Priouret, M.; Garcia, M. P.; Schroeter, M.; Camp, J. G.; Treutlein, B.
10.1101/2023.12.12.571318 — bioengineering — Posted on 2023-12-20
1382 Island demographics and trait associations in white-tailed deer
Cars, B. S.; Kessler, C.; Hoffman, E. A.; Cote, S. D.; Koelsch, D.; Shafer, A. B.
10.1101/2023.08.01.551454 — genomics — Posted on 2023-12-20
1383 Preventing multiple resistance above all: new insights for managing fungal adaptation
Ballu, A.; Ugazio, C.; Duplaix, C.; Noly, A.; Wullschleger, J.; Torriani, S. F. F.; Deredec, A.; Carpentier, F.; Walker, A.-S.
10.1101/2022.12.17.520869 — evolutionary biology — Posted on 2023-12-20
1384 Genomic evidence for West Antarctic Ice Sheet collapse during the Last Interglacial
Lau, S. C. Y.; Wilson, N. G.; Golledge, N. R.; Naish, T. R.; Watts, P. C.; Silva, C. N. S.; Cooke, I. R.; Allcock, A. L.; Mark, F. C.; Linse, K.; Strugnell, J. M.
10.1101/2023.01.29.525778 — evolutionary biology — Posted on 2023-12-20
1385 Global Biogeography of the Soil Virosphere
Graham, E. B.; Camargo, A. P.; Wu, R.; Neches, R. Y.; Nolan, M.; Paez-Espino, D.; Copeland, A.; Kyrpides, N.; Jansson, J. K. K.; McDermott, J. E.; Hofmockel, K. S.; Soil Virosphere Consortium,
10.1101/2023.11.02.565391 — ecology — Posted on 2023-12-20
1387 Differential Functional Consequences of GRIN2A Mutations Associated with Schizophrenia and Neurodevelopmental Disorders
Shepard, N.; Baez-Nieto, D.; Iqbal, S.; Kurganov, E.; Budnik, N.; Campbell, A. J.; Pan, J. Q.; Sheng, M.; Farsi, Z.
10.1101/2023.08.02.551645 — neuroscience — Posted on 2023-12-20
1388 Machine learning of brain-specific biomarkers from EEG
Bomatter, P.; Paillard, J.; Garces, P.; Hipp, J. F.; Engemann, D. A.
10.1101/2023.12.15.571864 — neuroscience — Posted on 2023-12-20
1389 Material Properties of Nonpregnant and Pregnant Human Uterine Layers
Fodera, D. M.; Russell, S. R.; Lund-Jackson, J. L.; Fang, S.; Chen, X.; Vink, J.-S. Y.; Oyen, M. L.; Myers, K. M.
10.1101/2023.08.07.551726 — bioengineering — Posted on 2023-12-20
1392 SGLT2 inhibitors attenuate endothelial to mesenchymal transition and cardiac fibroblast activation
Schmidt, K.; Schmidt, A.; Gross, S.; Just, A.; Pfanne, A.; Fuchs, M.; Jordan, M.; Mohr, E.; Pich, A.; Fiedler, J.; Thum, T.
10.1101/2023.12.18.572273 — pharmacology and toxicology — Posted on 2023-12-20
1393 Large pan-cancer cell screen coupled to (phospho-) proteomics underscores high-dose vitamin C as a potent anti-cancer agent
Valles Marti, A.; Böttger, F.; Yau, E.; Tejjani, K.; Meijs, L.; Sharma, S.; Mumtaz, M.; Le Large, T.; Erozenci, A.; Dekker, D.; Schelfhorst, T.; Medema, J. P.; Bijnsdorp, I. V.; Knol, J. C.; Piersma, S. R.; Pham, T. V.; Giovannetti, E.; Jimenez, C. R.
10.1101/2023.12.19.572293 — cancer biology — Posted on 2023-12-20
1394 A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines
Lee, J.; Stewart, C.; Schaefer, A.; Leaf, E. M.; Park, Y.-J.; Asarnow, D.; Powers, J. M.; Treichel, C.; Corti, D.; Baric, R.; King, N. P.; Veesler, D.
10.1101/2023.12.12.571160 — biochemistry — Posted on 2023-12-20
1395 Chromosome-level genome assembly of the European Green woodpecker Picus viridis
Forest, T.; Achaz, G.; Marbouty, M.; Bignaud, A.; Thierry, A.; Koszul, R.; Milhes, M.; Lledo, J.; Pons, J.-M.; Fuchs, J.
10.1101/2023.12.18.572251 — genomics — Posted on 2023-12-20
1396 WITHDRAWN: Recombinant BCG overexpressing a STING agonist elicits trained immunity and improved antitumor efficacy in non-muscle invasive bladder
Singh, A. K.; Praharaj, M.; Lombardo, K. A.; Yoshida, T.; Matoso, A.; Baras, A. S.; Zhao, L.; Prasad, P.; Powell, J. D.; Kates, M.; McConkey, D.; Pardoll, D. M.; Bishai, W. R.; Bivalacqua, T. J.
10.1101/2020.04.25.061531 — cancer biology — Posted on 2023-12-20
1398 Novel Association of Lyme Disease, Age, and Atopic Dermatitis
Lee, B. T.; Galloway, S.; Feng, Q.; Strausz, S.; Hansen, P.; Torrez-Dulgeroff, L. B.; Blacker, G.; Yiu, Y. Y.; Mansfield, P.; FinnGen, ; Saleem, A.; Gars, E.; Sanders, E.; Weissman, I. L.; Ollila, H.; Tal, M. C.
10.1101/2022.01.27.476641 — immunology — Posted on 2023-12-20
1401 Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis
Bannoura, S. F.; Aboukameel, A.; Khan, H. Y.; Uddin, M. H.; Jang, H.; Beal, E.; Thangasamy, A.; Kim, S.; Wagner, K.-U.; Mohammad, R.; Al Hallak, M. N.; Pasche, B.; Azmi, A. S.
10.1101/2023.12.18.572102 — cancer biology — Posted on 2023-12-19
1404 Positive selection in gamete interaction proteins in Carnivora
Pisciottano, F.; Campos, M. C.; Penna, C.; Bruque, C. D.; Gabaldon, T.; Saragueta, P.
10.1101/2022.03.22.485370 — evolutionary biology — Posted on 2023-12-19
1405 Small RNAs from Mitochondrial Genome Recombination Sites are Incorporated into T. gondii Mitoribosomes
Tetzlaff, S.; Hillebrand, A.; Drakoulis, N.; Gluhic, Z.; Maschmann, S.; Lyko, P.; Wicke, S.; Schmitz-Linneweber, C.
10.1101/2023.09.02.556019 — molecular biology — Posted on 2023-12-19
1408 AtERF60, negatively regulates ABR1 to modulate basal resistance response in Arabidopsis
Joshi, A.; Phukan, U. J.; Singh, N.; Jeena, G. S.; Kumar, S.; Pandey, D. K.; Pandey, A.; Tripathi, V.; Shukla, R.
10.1101/2021.12.29.474403 — plant biology — Posted on 2023-12-19
1409 Specialization of the Human Hippocampal Long Axis Revisited
Angeli, P. A.; DiNicola, L. M.; Saadon-Grosman, N.; Eldaief, M. C.; Buckner, R. L.
10.1101/2023.12.19.572264 — neuroscience — Posted on 2023-12-19
1413 Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics
Walker, T. J.; Reyes-Alvarez, E.; Hyndman, B. D.; Sugiyama, M. G.; Oliveira, L. C. B.; Rekab, A. N.; Crupi, M. J. F.; Cabral-Dias, R.; Guo, Q.; Dahia, P. L. M.; Richardson, D. S.; Antonescu, C. N.; Mulligan, L. M.
10.1101/2023.06.28.546955 — cancer biology — Posted on 2023-12-19
1414 Structural and mechanistic insights into human choline and ethanolamine transport
Ri, K.; Weng, T.-H.; Claveras Cabezudo, A.; Jösting, W.; Yu, Z.; Bazzone, A.; Leong, N. C. P.; Welsch, S.; Doty, R. T.; Gursu, G.; Lim, T. J. Y.; Schmidt, S. L.; Abkowitz, J. L.; Hummer, G.; Wu, D.; Nguyen, L. N.; Safarian, S.
10.1101/2023.09.15.557925 — biophysics — Posted on 2023-12-19
1418 T7 DNA polymerase treatment improves quantitative sequencing of both double-stranded and single-stranded DNA viruses
Petit, M.-A.; Billaud, M.; Theodorou, I.; Shah, S. A.; De Sordi, L.; De Paepe, M.; Lamy-Besnier, Q.
10.1101/2022.12.12.520144 — genomics — Posted on 2023-12-19
1420 Multi-trait GWAS for diverse ancestries: Mapping the knowledge gap
Troubat, L.; Fettahoglu, D.; Henches, L.; Aschard, H.; Julienne, H.
10.1101/2023.06.23.546248 — genetics — Posted on 2023-12-19
1421 Genetic similarity between relatives provides evidence on the presence and history of assortative mating
Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.
10.1101/2023.06.27.546663 — genetics — Posted on 2023-12-19
1422 Identification of arginine-vasopressin receptor 1a (Avpr1a/AVPR1A) as a novel candidate gene for chronic visceral pain.
Kader, L.; Willits, A.; Meriano, S. A.; Christianson, J. A.; La, J.-H.; Feng, B.; Knight, B.; Kosova, G.; Deberry, J.; Coates, M.; Hyams, J.; Baumbauer, K.; Young, E. E.
10.1101/2023.12.19.572390 — genetics — Posted on 2023-12-19
1424 The interplay of TGF-β1 and cholesterol orchestrating hepatocyte cell fate, EMT, and signals for HSC activation
Wang, S.; Link, F.; Han, M.; Chaudhary, R.; Asimakopoulos, A.; Liebe, R.; Yao, Y.; Hammad, S.; Dropmann, A.; Krizanac, M.; Rubie, C.; Feiner, L. K.; Glanemann, M.; Ebert, M.; Weiskirchen, R.; Henis, Y. I.; Ehrlich, M.; Dooley, S.
10.1101/2023.08.14.552900 — cell biology — Posted on 2023-12-19
1427 The human Dicer helicase domain mediates ATP hydrolysis and RNA rearrangement
Ciechanowska, K.; Szczepanska, A.; Szpotkowski, K.; Wojcik, K.; Urbanowicz, A.; Kurzynska-Kokorniak, A.
10.1101/2023.06.28.546842 — molecular biology — Posted on 2023-12-19
1428 Persistence of backtracking by human RNA polymerase II
Yang, K. B.; Rasouly, A.; Epshtein, V.; Martinez, C.; Nguyen, T.; Shamovsky, I.; Nudler, E.
10.1101/2023.12.13.571520 — molecular biology — Posted on 2023-12-19
1429 Bacterial pathogens dynamic during multi-species infections
Barny, M.-A.; Thieffry, S.; Gomes de Faria, C.; Thebault, E.; Pedron, J.
10.1101/2023.12.06.570389 — microbiology — Posted on 2023-12-19
1430 Parkinson's disease-related Miro1 mutation induces mitochondrial dysfunction and loss of dopaminergic neurons in vitro and in vivo
Chemla, A.; Arena, G.; Sacripanti, G.; Barmpa, K.; Zagare, A.; Garcia, P.; Antony, P.; Ohnmacht, J.; Baron, A.; Jung, J.; Marzesco, A.-M.; Buttini, M.; Schmidt, T.; Grunewald, A.; Schwamborn, J. C.; Kruger, R.; Saraiva, C.
10.1101/2023.12.19.571978 — neuroscience — Posted on 2023-12-19
1431 Synaptic strength dynamics at cortical pathways is encoded by vigilance states duration
Marchal, P.; Salin, P.; Missaire, M.; Rampon, M.; Carponcy, J.; Parmentier, R.; Poe, G.; Malleret, G.; Comte, J.-C.
10.1101/2023.11.22.567828 — neuroscience — Posted on 2023-12-19
1434 Systematic benchmarking of imaging spatial transcriptomics platforms in FFPE tissues
Wang, H.; Huang, R.; Nelson, J.; Gao, C.; Tran, M.; Yeaton, A.; Felt, K.; Pfaff, K. L.; Bowman, T.; Rodig, S. J.; Wei, K.; Goods, B. A.; Farhi, S. L.
10.1101/2023.12.07.570603 — cancer biology — Posted on 2023-12-19
1438 Diverse prey capture strategies in teleost larvae
Mearns, D. S.; Hunt, S. A.; Schneider, M. W.; Parker, A. V.; Stemmer, M.; Baier, H.
10.1101/2023.10.03.560453 — animal behavior and cognition — Posted on 2023-12-19
1440 A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system
Belgrad, J.; Tang, Q.; Hildebrand, S.; Summers, A.; Sapp, E.; Echeverria, D.; O'Reilly, D.; Luu, E.; Bramato, B.; Allen, S.; Cooper, D.; Alterman, J.; Yamada, K.; Aronin, N.; DiFiglia, M.; Khvorova, A.
10.1101/2023.12.19.572404 — molecular biology — Posted on 2023-12-19
1441 CDCA7 is a hemimethylated DNA adaptor for the nucleosome remodeler HELLS
Wassing, I. E.; Nishiyama, A.; Hiruta, M.; Jia, Q.; Shikimachi, R.; Kikuchi, A.; Sugimura, K.; Hong, X.; Chiba, Y.; Peng, J.; Jenness, C.; Nakanishi, M.; Zhao, L.; Arita, K.; Funabiki, H.
10.1101/2023.12.19.572350 — molecular biology — Posted on 2023-12-19
1442 Enhancement of antibody thermostability and affinity by computational design in the absence of antigen
Hutchinson, M.; Ruffolo, J. A.; Haskins, N.; Iannotti, M.; Vozza, G.; Pham, T.; Mehzabeen, N.; Shandilya, H.; Rickert, K.; Croasdale-Wood, R.; Damschroder, M.; Fu, Y.; Dippel, A.; Gray, J. J.; Kaplan, G.
10.1101/2023.12.19.572421 — molecular biology — Posted on 2023-12-19
1443 Modulation of prion protein expression through cryptic splice site manipulation
Gentile, J. E.; Corridon, T. L.; Mortberg, M. A.; D'Souza, E. N.; Whiffin, N.; Minikel, E. V.; Vallabh, S. M.
10.1101/2023.12.19.572439 — molecular biology — Posted on 2023-12-19
1444 Regulation of lactose and galactose growth: Insights from a unique metabolic gene cluster in Candida intermedia
Peri, K. V. R.; Yuan, L.; Faria Oliveira, F.; Persson, K.; Alalam, H. D.; Olsson, L.; Larsbrink, J.; Kerkhoven, E. J.; Geijer, C.
10.1101/2023.12.19.572343 — microbiology — Posted on 2023-12-19
1446 Direct comparison of SARS-CoV-2 variant specific neutralizing antibodies in human and hamster sera
Roessler, A.; Netzl, A.; Knabl, L.; Wilks, S. H.; Muehlemann, B.; Tuereli, S.; Mykytyn, A.; von Laer, D.; Haagmans, B. L.; Smith, D. J.; Kimpel, J.
10.1101/2023.12.19.572347 — immunology — Posted on 2023-12-19
1447 Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates
Malewana, R. D.; Stalls, V.; May, A.; Lu, X.; Martinez, D. R.; Schafer, A.; Li, D.; Barr, M.; Sutherland, L. L.; Lee, E.; Parks, R.; Beck, W. E.; Newman, A.; Bock, K. W.; Minai, M.; Nagata, B. M.; DeMarco, C. T.; Denny, T. N.; Oguin, T. H.; Rountree, W.; Wang, Y.; Mansouri, K.; Edwards, R. J.; Sempowski, G. D.; Eaton, A.; Muramatsu, H.; Henderson, R.; Tam, Y.; Barbosa, C.; Tang, J.; Cain, D. W.; Santra, S.; Moore, I. N.; Andersen, H.; Lewis, M. G.; Golding, H.; Seder, R.; Khurana, S.; Montefiori, D. C.; Pardi, N.; Weissman, D.; Baric, R. S.; Acharya, P.; Haynes, B. F.; Saunders, K. O.
10.1101/2023.12.18.572191 — immunology — Posted on 2023-12-19
1448 Essential magnetosome proteins MamI and MamL from magnetotactic bacteria interact in mammalian cells
Sun, Q.; Yu, L.; Donnelly, S. C.; Fradin, C.; Thompson, R. T.; Prato, F. S.; Goldhawk, D. E.
10.1101/2023.12.19.572379 — synthetic biology — Posted on 2023-12-19
1449 Continual improvement of multiplex mutagenesis in Arabidopsis
Develtere, W.; Decaestecker, W.; Rombaut, D.; Anders, C.; Clicque, E.; Vuylsteke, M.; Jacobs, T. B.
10.1101/2023.12.19.572307 — synthetic biology — Posted on 2023-12-19
1450 Phase diversity-based wavefront sensing for fluorescence microscopy
Johnson, C.; Guo, M.; Schneider, M. C.; Su, Y.; Khuon, S. C.; Reiser, N.; Wu, Y.; La Riviere, P. J.; Shroff, H.
10.1101/2023.12.19.572369 — bioengineering — Posted on 2023-12-19
1453 A new method for the reproducible development of aptamers (Neomers)
Meehan, C.; Hamilton, E. L.; Mansour, C. G.; Lecocq, S.; Drake, C. J.; An, Y.; Rodrigues, E.; Penner, G.
10.1101/2023.12.19.572437 — biochemistry — Posted on 2023-12-19
1454 Live-imaging reveals Coordinated Cell Migration and Cardiac Fate Determination during Mammalian Gastrulation.
Abukar, S.; Embacher, P.; Cicarrelli, A.; Varsani-Brown, S.; Dean, J. A.; Briscoe, J.; Ivanovitch, k.
10.1101/2023.12.19.572445 — developmental biology — Posted on 2023-12-19
1455 Multi-target mode of action of Sulfodyne(R), a stabilized Sulforaphane, against pathogenic effects of SARS-CoV-2 infection
Romeo, P.-H.; Conquet, L.; Messiaen, S.; Pascal, Q.; Moreno, S. G.; Bravard, A.; Bernardino-Sgherri, J.; Dereuddre-Bosquet, N.; Montagutelli, X.; Le Grand, R.; Petit, V.; Ferri, F.
10.1101/2023.12.18.572126 — cell biology — Posted on 2023-12-19
1456 Mantis: high-throughput 4D imaging and analysis of the molecular and physical architecture of cells
Ivanov, I. E.; Hirata-Miyasaki, E.; Chandler, T.; Kovilakam, R. C.; Liu, Z.; Liu, C.; Leonetti, M. D.; Huang, B.; Mehta, S. B.
10.1101/2023.12.19.572435 — cell biology — Posted on 2023-12-19
1457 Comparison of mitochondrial response to SARS-CoV-2 spike protein receptor binding domain in human lung microvascular, coronary artery endothelial and bronchial epithelial cells
Kulkoviene, G.; Narauskaite, D.; Tunaityte, A.; Volkeviciute, A.; Balion, Z.; Kutakh, O.; Gecys, D.; Kairyte, M.; Uldukyte, M.; Stankevicius, E.; Jekabsone, A.
10.1101/2023.12.19.572363 — immunology — Posted on 2023-12-19
1458 Neuropathological assessment of the olfactory bulb and tract in individuals with COVID-19
Lengacher, N. A.; Tomlinson, J. J.; Jochum, A.-K.; Franz, J.; Hasan Ali, O.; Flatz, L.; Jochum, W.; Penninger, J.; aSCENT-PD Investigators, ; Stadelmann-Nessler, C.; Woulfe, J. M.; Schlossmacher, M. G.
10.1101/2023.12.18.572180 — pathology — Posted on 2023-12-19
1462 eRNA-IDO: a one-stop platform for identification, interactome discovery and functional annotation of enhancer RNAs
Zhang, Y.; Gong, L.; Ding, R.; Chen, W.; Rong, H.; Li, Y.; Shameem, F.; Ali, K. A.; Li, L.; Liao, Q.
10.1101/2023.12.19.572028 — bioinformatics — Posted on 2023-12-19
1464 Structure of an insect gustatory receptor
Frank, H. M.; Walujkar, S.; Walsh, R. M.; Laursen, W. J.; Theobald, D. L.; Garrity, P. A.; Gaudet, R.
10.1101/2023.12.19.572336 — biochemistry — Posted on 2023-12-19
1467 PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis
Belmonte, B.; Di Lorenzo, G.; Mangogna, A.; Bortot, B.; Bertolazzi, G.; Sammataro, S.; Merighi, S.; Martorana, A.; Zito, G.; Romano, F.; Giorgiutti, A.; Bottin, C.; Zanconati, F.; Romano, A.; Ricci, G.; Biffi, S.
10.1101/2023.12.19.572311 — cell biology — Posted on 2023-12-19
1468 The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
Timimi, L.; Wrobel, A. G.; Chiduza, G. N.; Maslen, S. L.; Torres-Mendez, A.; Montaner, B.; Davis, C.; Skehel, M.; Rubinstein, J. L.; Schreiber, A. L.; Beale, R.
10.1101/2023.12.19.572309 — molecular biology — Posted on 2023-12-19
1469 Air monitoring by nanopore sequencing
Reska, T.; Pozdniakova, S.; Borras, S.; Schloter, M.; Canas, L.; Fenn, A.; Rodo, X.; Winkler, B.; Schnitzler, J.-P.; Urban, L.
10.1101/2023.12.19.572325 — molecular biology — Posted on 2023-12-19
1470 Antibiotic treatment does not abrogate protection against Mycobacterium tuberculosis reinfection
Ganchua, S. K.; Maiello, P.; Chao, M.; Hopkins, F.; Mugahid, D.; Lin, P. L.; Fortune, S. M.; Flynn, J. L.
10.1101/2023.12.19.570845 — microbiology — Posted on 2023-12-19
1471 Comparison of Multiple Carbapenemase Tests Based on an Unbiased Colony Selection Method
Wang, H.-Y.; Tseng, Y.-J.; Lin, W.-Y.; Wang, Y.-C.; Lin, T.-W.; Hsu, J.-F.; Wu, M. Y.-C.; Wu, C.-H.; Kalpana, S.; Lu, J.-J.
10.1101/2023.12.19.572349 — microbiology — Posted on 2023-12-19
1475 The actin-spectrin submembrane scaffold restricts endocytosis along proximal axons
Wernert, F.; Moparthi, S. B.; Laine, J.; Moulay, G.; Boroni-Rueda, F.; Pelletier, F.; Jullien, N.; Benkhelifa-Ziyat, S.; Papandreou, M.-J.; Leterrier, C.; Vassilopoulos, S.
10.1101/2023.12.19.572337 — cell biology — Posted on 2023-12-19
1480 Robust detection of SARS-CoV-2 exposure in population using T-cell repertoire profiling
Vlasova, E. K.; Nekrasova, A. I.; Komkov, A. Y.; Izraelson, M.; Snigir, E. A.; Mitrofanov, S. I.; Yudin, V. S.; Makarov, V. V.; Kesnikov, A. A.; Korneeva, D.; Pivnyuk, A.; Shelyakin, P. V.; Mamedov, I. Z.; Rebrikov, D. V.; Chudakov, D. M.; Yudin, S. M.; Skvortsova, V. I.; Britanova, O.; Shugay, M. A.
10.1101/2023.11.08.566227 — immunology — Posted on 2023-12-19
1482 Vagal interoception of microbial metabolites from the small intestinal lumen
Jameson, K. G.; Kazmi, S. A.; Son, C.; Mazdeyasnan, D.; Leshan, E.; Vuong, H. E.; Paramo, J.; Lopez-Romero, A.; Schweizer, F. E.; Yang, L.; Hsiao, E. Y.
10.1101/2023.12.18.572257 — neuroscience — Posted on 2023-12-19
1483 Regional response to light illuminance across the human hypothalamus
Campbell, I.; Sharifpour, R.; Balda, F.; Beckers, E.; Paparella, I.; Berger, A.; Koshmanova, E.; Mortazavi, N.; Read, J.; Zubkov, M.; Talwar, P.; Collette, F.; Sherif, S.; Phillips, C.; Lamalle, L.; Vandewalle, G.
10.1101/2023.12.19.572317 — neuroscience — Posted on 2023-12-19
1485 Mutation of OsCDS5 confers broad-spectrum disease resistance in rice
Sun, Q.; Xiao, Y.; Song, L.; Yang, L.; Wang, Y.; Yang, W.; Yang, Q.; Xie, K.; Yuan, M.; Li, G.
10.1101/2023.12.18.572258 — plant biology — Posted on 2023-12-19
1486 GSK3β phosphorylation catalyzes the aggregation of Tau into Alzheimer's disease-like amyloid strain
Chakraborty, P.; Ibanez de Opakua, A.; Purslow, J. A.; Fromm, S. A.; Chatterjee, D.; Zachrdla, M.; Puri, S.; Wolozin, B.; Zweckstetter, M.
10.1101/2023.12.19.572292 — biophysics — Posted on 2023-12-19
1490 Temporal recording of mammalian development and precancer
Islam, M.; Yang, Y.; Simmons, A. J.; Shah, V. M.; Pavan, M. K.; Xu, Y.; Tasneem, N.; Chen, Z.; Trinh, L. T.; Molina, P.; Ramirez-Solano, M. A.; Sadien, I.; Dou, J.; Chen, K.; Magnuson, M. A.; Rathmell, J.; Macara, I. G.; Winton, D. J.; Liu, Q.; Zafar, H.; Kalhor, R.; Church, G. M.; Shrubsole, M. J.; Coffey, R. J.; Lau, K.
10.1101/2023.12.18.572260 — developmental biology — Posted on 2023-12-19
1492 Norovirus NS1/2 protein increases glutaminolysis for efficient viral replication
Hafner, A.; Meurs, N.; Garner, A.; Azar, E.; Passalacqua, K. D.; Nagrath, D.; Wobus, C. E.
10.1101/2023.12.19.572316 — microbiology — Posted on 2023-12-19
1495 Structural and practical identifiability of contrast transport models for DCE-MRI
Conte, M.; Woodall, R. T.; Gutova, M.; Chen, B. T.; Shiroishi, M. S.; Brown, C. C.; Munson, J. M.; Rockne, R. C.
10.1101/2023.12.19.572294 — systems biology — Posted on 2023-12-19
1497 Spatial transcriptomics analysis identifies a unique tumor-promoting function of the meningeal stroma in melanoma leptomeningeal disease
Alhaddad, H.; Ospina, O. E.; Khaled, M. L.; Ren, Y.; Forsyth, P. A.; Pina, Y.; Macaulay, R.; Law, V.; Tsai, K. Y.; Cress, W. D.; Fridley, B.; Smalley, I.
10.1101/2023.12.18.572266 — cancer biology — Posted on 2023-12-19
1502 scResolve: Recovering single cell expression profiles from multi-cellular spatial transcriptomics
Chen, H.; Lee, Y. J.; Ovando, J. A.; Rosas, L.; Rojas, M.; Mora, A. L.; Bar-Joseph, Z.; Lugo-Martinez, J.
10.1101/2023.12.18.572269 — bioinformatics — Posted on 2023-12-19
1503 Predicting stop codon reassignment improves functional annotation of bacteriophages
Cook, R.; Telatin, A.; Bouras, G.; Camargo, A. P.; Larralde, M.; Edwards, R. A.; Adriaenssens, E. M.
10.1101/2023.12.19.572299 — bioinformatics — Posted on 2023-12-19
1507 A Bayesian active learning platform for scalable combination drug screens
Tosh, C.; Tec, M.; White, J.; Quinn, J. F.; Ibanez Sanchez, G.; Calder, P.; Kung, A. L.; Dela Cruz, F. S.; Tansey, W.
10.1101/2023.12.18.572245 — bioinformatics — Posted on 2023-12-19
1509 The current landscape and emerging challenges of benchmarking single-cell methods
Yang, J. Y. H.; Cao, Y.; Yu, L.; Torkel, M.; Kim, S.; Lin, Y.; Yang, P.; Speed, T. P.; Ghazanfar, S.
10.1101/2023.12.19.572303 — bioinformatics — Posted on 2023-12-19
1514 CytoCellDB: A Resource Database For Classification and Analysis of Extrachromosomal DNA in Cancer
Fessler, J.; Ting, S.; Yi, H.; Haase, S.; Chen, J.; Gulec, S.; Wang, Y.; Smyers, N.; Goble, K.; Cannon, D.; Mehta, A.; Ford, C.; Brunk, E. C.
10.1101/2023.12.18.572197 — genomics — Posted on 2023-12-19
1520 The Developmental Transcription Factor TBX3 Physically Engages with the Wnt/β-catenin Transcriptional Complex in Human Colorectal Cancer Cells to Regulate Metastasis Genes
Jauregi-Miguel, A.; Soderholm, S.; Weiss, T. L.; Nordin, A.; Ghezzi, V.; Bruetsch, S. M.; Pagella, P.; van de Grift, Y.; Zambanini, G.; Ulisse, J.; Mattias, A.; Deviatiiarov, R.; Faustini, E.; Moparthi, L.; Lottersberger, F.; Koch, S.; Moor, A. E.; Sun, X.-F.; von Castelmur, E.; Sheng, G.; Cantu', C.
10.1101/2023.12.18.571901 — developmental biology — Posted on 2023-12-19
1521 White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells
Yeung, S. H.-S.; Lee, R. H.-S.; Cheng, G. W.-Y.; Ma, I. W.-T.; Kofler, J.; Kent, C.; Ma, F.; Herrup, K.; Fornage, M.; Arai, K.; Tse, K.-H.
10.1101/2023.12.18.566359 — cell biology — Posted on 2023-12-19
1522 Single-cell analysis reveals lasting immunological consequences of influenza infection and respiratory immunisation in the pig lung
Muir, A.; Paudyal, B.; Schmidt, S.; Sedaghat-Rostani, E.; Chakravarti, S.; Villanueva Hernandez, S.; Moffat, K.; Polo, N.; Angelopoulos, N.; Schmidt, A.; Tenbusch, M.; Freimanis, G.; Gerner, W.; Richard, A. C.; Tchilian, E.
10.1101/2023.12.19.572318 — immunology — Posted on 2023-12-19
1523 Single-cell transcriptomics reveals heterogenous thymic dendritic cell subsets with distinct functions and requirements for thymocyte-regulated crosstalk
Srinivasan, J.; Helm, B. R.; Yang, Y.; Moore, C.; Moore, J. F.; Calindi, A.; Selden, H. J.; Heiser, C. N.; Liu, Q.; Lau, K.; Ehrlich, L. I. R.
10.1101/2023.12.18.572281 — immunology — Posted on 2023-12-19
1528 Age-dependent Powassan Virus Lethality is Directed by Glial Cell Activation and Divergent Neuroinflammatory Cytokine Responses in a Murine Model
Mladinich, M. C.; Himmler, G.; Conde, J. N.; Gorbunova, E.; Schutt, W. R.; Sarkar, S.; Tsirka, S.-A.; Kim, H. K.; Mackow, E. R.
10.1101/2023.12.18.572230 — microbiology — Posted on 2023-12-19
1532 Missense mutations in CMS22 patients reveal that PREPL has both enzymatic and non-enzymatic functions
Monnens, Y.; Theodoropoulou, A.; Rosier, K.; Bhalla, K.; Mahy, A.; Vanhoutte, R.; Meulemans, S.; Cavani, E.; Antanasijevic, A.; Lemmens, I.; Lee, J. A.; Spellicy, C. J.; Schroer, R. J.; Masalli, R. A.; Laverty, C. G.; Agostinis, P.; Pagliarini, D.; Verhelst, S.; Marcaida, M. J.; Rochtus, A.; Dal Peraro, M.; Creemers, J. W. M.
10.1101/2023.12.18.572145 — genetics — Posted on 2023-12-19
1534 Nitrogen signaling factor triggers a respiration-like gene expression program
Buehler, M.; Ohsawa, S.; Schwaiger, M.; Iesmantavicius, V.; Hashimoto, R.; Moriyama, H.; Matoba, H.; Hirai, G.; Sodeoka, M.; Hashimoto, A.; Matsuyama, A.; Yoshida, M.; Yashiroda, Y.
10.1101/2023.12.18.572203 — microbiology — Posted on 2023-12-19
1538 RSPO/LGR signaling mediates astrocyte-induced proliferation of adult hippocampal neural stem cells
Valenzuela-Bezanilla, D.; Mardones, M. D.; Galassi, M.; Arredondo, S. B.; Santibanez, S. H.; Merino-Veliz, N.; Bustos, F. J.; Varela-Nallar, L.
10.1101/2023.12.18.572207 — neuroscience — Posted on 2023-12-19
1539 Whole-brain modular dynamics at rest predict sensorimotor learning performance
Standage, D. I.; Gale, D. J.; Nashed, J. Y.; Flanagan, J. R.; Gallivan, J. P.
10.1101/2023.12.18.572267 — neuroscience — Posted on 2023-12-19
1541 A compendium of Amplification-Related Gain Of Sensitivity (ARGOS) genes in human cancer
Rendo, V.; Schubert, M.; Khuu, N.; Suarez Peredo Rodriguez, M. F.; Huang, K.; Swift, M.; He, Y.; Zerbib, J.; Smith, R.; Raaijmakers, J.; Bandopadhayay, P.; Guenther, L. M.; Hwang, J. H.; Iniguez, A.; Moody, S.; Seo, J.-H.; Stover, E.; Garraway, L.; Hahn, W. C.; Stegmaier, K.; Medema, R. H.; Chowdhury, D.; Colome-Tatche, M.; Ben-David, U.; Beroukhim, R.; Foijer, F.
10.1101/2023.12.16.571980 — cancer biology — Posted on 2023-12-19
1543 Differential detection workflows for multi-sample single-cell RNA-seq data
Gilis, J.; Perin, L.; Malfait, M.; Van den Berge, K.; Assefa Takele, A.; Verbist, B.; Risso, D.; Clement, L.
10.1101/2023.12.17.572043 — bioinformatics — Posted on 2023-12-19
1545 UVAE: Integration of Heterogeneous Unpaired Data with Imbalanced Classes
Phuycharoen, M.; Kaestele, V.; Williams, T.; Lin, L.; Hussell, T.; Grainger, J.; Rattray, M.
10.1101/2023.12.18.572157 — bioinformatics — Posted on 2023-12-19
1546 Arctos: Community-driven innovations for managing biodiversity and cultural collections
Cicero, C.; Koo, M. S.; Braker, E.; Abbott, J.; Bloom, D.; Campbell, M.; Cook, J. A.; Demboski, J. R.; Doll, A. C.; Frederick, L. M.; Linn, A. J.; Mayfield-Meyer, T. J.; McDonald, D.; Nachman, M. W.; Olson, L. E.; Roberts, D.; Sikes, D. S.; Witt, C. C.; Wommack, E.
10.1101/2023.12.15.571899 — bioinformatics — Posted on 2023-12-19
1549 Identification of methylation markers for age and Bovine Respiratory Disease in dairy cattle
Attree, E.; Griffiths, B.; Panchal, K.; Xia, D.; Werling, D.; Banos, G.; Oikonomou, G.; Psifidi, A.
10.1101/2023.12.18.572169 — genetics — Posted on 2023-12-19
1553 Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity
Batorsky, R.; Ceasrine, A. M.; Shook, L. L.; Kislal, S.; Bordt, E. A.; Devlin, B. A.; Perlis, R. H.; Slonim, D. K.; Bilbo, S. D.; Edlow, A. G.
10.1101/2023.12.16.571680 — developmental biology — Posted on 2023-12-19
1554 Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan
Yano, H.; Hayashi, W.; Kawakami, S.; Aoki, S.; Anzai, E.; Kitamura, N.; Hirabayashi, A.; Kajihara, T.; Kayama, S.; Sugawara, Y.; Yahara, K.; Sugai, M.
10.1101/2023.12.17.572044 — microbiology — Posted on 2023-12-19
1555 A special role for anterior cingulate cortex, but not orbitofrontal cortex or basolateral amygdala, in choices involving information
Gonzalez, V. V.; Ashikyan, S. A.; Zhang, Y.; Rickard, A.; Yassine, I.; Romero-Sosa, J. L.; Blaisdell, A. P.; Izquierdo, A.
10.1101/2023.08.03.551514 — neuroscience — Posted on 2023-12-19
1556 Machine learning of brain-specific biomarkers from EEG
Bomatter, P.; Paillard, J.; Garces, P.; Hipp, J. F.; Engemann, D. A.
10.1101/2023.12.15.571864 — neuroscience — Posted on 2023-12-19
1563 Encapsulation of AAVs into protein vault nanoparticles as a novel solution to gene therapy's neutralizing antibody problem
Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lagor, W.; Bao, G.; Ponnazhagan, S.; McNally, R.; Rome, L.; Curiel, D.
10.1101/2023.11.29.569229 — bioengineering — Posted on 2023-12-19
1566 Maternal SMARCA5 is required for major ZGA in mouse embryos
Kubinyecz, O. N.; Drage, D.; Santos Constancia, M. d. F.; Krueger, C.; Okkenhaug, H.; Alda-Catalinas, C.; Eckersley-Maslin, M.; Taubenschmid-Stowers, J.; Reik, W.
10.1101/2023.12.05.570276 — developmental biology — Posted on 2023-12-19
1569 PHEIGES, all-cell-free phage synthesis and selection from engineered genomes
Levrier, A.; Karpathakis, I.; Nash, B.; Bowden, S. D.; Lindner, A. B.; Noireaux, V.
10.1101/2023.12.07.570578 — synthetic biology — Posted on 2023-12-19
1571 Rapid propagation of Ca2+ waves and electrical signals in a liverwort Marchantia polymorpha
Watanabe, K.; Hashimoto, K.; Hasegawa, K.; Shindo, H.; Tsuruda, Y.; Kupisz, K.; Koselski, M.; Wasko, P.; Trebacz, K.; Kuchitsu, K.
10.1101/2023.10.16.562169 — plant biology — Posted on 2023-12-19
1572 RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds
Fu, B.; Brock, E. E.; Andrews, R.; Breiter, J. C.; Tian, R.; Toomey, C. E.; Lachica, J.; Lashley, T.; Ryten, M.; Wood, N. W.; Vendruscolo, M.; Gandhi, S.; Weiss, L. E.; Beckwith, J. S.; Lee, S. F.
10.1101/2023.12.18.572148 — biophysics — Posted on 2023-12-19
1578 Endocardial HDAC3 is required for myocardial trabeculation
Jang, J.; Bentsen, M.; Kim, Y. J.; Kim, E.; Garg, V.; Cai, C.-L.; Looso, M.; Li, D.
10.1101/2023.04.12.536668 — developmental biology — Posted on 2023-12-19
1582 Thiolutin has complex effects in vivo but is a direct inhibitor of RNA Polymerase II in vitro
Qiu, C.; Arora, P.; Malik, I.; Laperuta, A. J.; Pavlovic, E. M.; Ugochukwu, S.; Naik, M. T.; Kaplan, C. D.
10.1101/2021.05.05.442806 — molecular biology — Posted on 2023-12-19
1583 Nitrosative stress under microaerobic conditions triggers inositol metabolism in Pseudomonas extremaustralis
Venero, E. C. S.; Giambartolomei, L.; Sosa, E.; Fernandez do Porto, D.; Lopez, N. I.; Tribelli, P. M.
10.1101/2023.10.08.561431 — microbiology — Posted on 2023-12-19
1585 Translating from mice to humans: using preclinical blood-based biomarkers for the prognosis and treatment of traumatic brain injury
Lisi, I.; Moro, F.; Mazzone, E.; Marklund, N.; Pischiutta, F.; Kobeissy, F.; Mao, X.; Corrigan, F.; Helmy, A.; Nasrallah, F.; Di Pietro, V.; Ngwenya, L.; Portela, L. V.; Semple, B. D.; Smith, D. H.; Wellington, C.; Loane, D.; Wang, K. K.; Zanier, E. R.; InTBIR Fundamental & Translational Working Group,
10.1101/2023.12.01.569152 — neuroscience — Posted on 2023-12-19
1587 Rapid modeling of an ultra-rare epilepsy variant in wild-type mice by in utero prime editing
Robertson, C. D.; Davis, P.; Richardson, R. R.; Iffland, P. H.; Vieira, D. C. O.; Steyert, M.; McKeon, P. N.; Romanowski, A. J.; Crutcher, G.; Jasarevic, E.; Wolff, S. B. E.; Mathur, B. N.; Crino, P. B.; Bale, T. L.; Dick, I. E.; Poulopoulos, A.
10.1101/2023.12.06.570164 — neuroscience — Posted on 2023-12-19
1589 Aging impairs skeletal muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution via fibro-adipogenic progenitors
Garcia-Carrizo, F.; Gohlke, S.; Lenihan-Geels, G.; Jank, A.-M.; Leer, M.; Soultoukis, G. A.; Oveisi, M.; Herpich, C.; Garrido, C. A.; Kotsaris, G.; Poehle-Kronawitter, S.; Tsamo-Tetou, A.; Graja, A.; Ost, M.; Villacorta, L.; Knecht, R. S.; Klaus, S.; Schuermann, A.; Stricker, S.; Schmidt-Bleek, K.; Cipitria, A.; Duda, G. N.; Benes, V.; Mueller-Werdan, U.; Norman, K.; Schulz, T. J.
10.1101/2023.11.27.568776 — physiology — Posted on 2023-12-19
1590 Mammary Tissue-Derived Extracellular Matrix Hydrogels Reveal the Role of Irradiation in Driving a Pro-Tumor and Immunosuppressive Microenvironment
Zhu, T.; Alves, S. M.; Adamo, A.; Wen, X.; Corn, K. C.; Shostak, A.; Johnson, S.; Shaub, N. D.; Martello, S. E.; Hacker, B. C.; D'Amore, A.; Bardhan, R.; Rafat, M.
10.1101/2022.05.16.492117 — cancer biology — Posted on 2023-12-19
1591 Cancer tissue of origin constrains the growth and metabolism of metastases
Sivanand, S.; Gultekin, Y.; Winter, P.; Vermeulen, S. Y.; Tchourine, K.; Abbott, K. L.; Danai, L. V.; Gourgue, F.; Do, B. T.; Crowder, K.; Kunchok, T.; Lau, A. N.; Darnell, A. M.; Jefferson, A.; Morita, S.; Duda, D. G.; Aguirre, A.; Wolpin, B. M.; Henning, N.; Spanoudaki, V.; Maiorino, L.; Irvine, D. J.; Yilmaz, O. H.; Lewis, C. A.; Vitkup, D.; Shalek, A. K.; Vander Heiden, M. G.
10.1101/2022.08.17.504141 — cancer biology — Posted on 2023-12-19
1592 Epigenetic disruption of the RARγ complex impairs its function to bookmark AR enhancer interactions required for enzalutamide sensitivity in prostate cancer
Wani, S. A.; Hussain, S.; Gray, J. S.; Nayak, D.; Tang, H.; Perez, L. M.; Long, M. D.; Siddappa, M.; McCabe, C.; Campbell, L.; Freeman, M. R.; Campbell, M. J.
10.1101/2023.12.15.571947 — cancer biology — Posted on 2023-12-19
1593 3D Cell Cultures Amplify Diffusion Signals
Arjmandi, H.; Kanebratt, K. P.; Vilen, L.; Gennemark, P.; Noel, A.
10.1101/2023.06.28.546952 — biophysics — Posted on 2023-12-19
1596 A novel clinical metaproteomics workflow enables bioinformatic analysis of host-microbe dynamics in disease
Do, K.; Mehta, S.; Wagner, R.; Bhuming, D.; Rajczewski, A. T.; Skubitz, A. P. N.; Johnson, J. E.; Griffin, T.; Jagtap, P.
10.1101/2023.11.21.568121 — bioinformatics — Posted on 2023-12-19
1598 Acquisition of Auditory Discrimination Mediated by Different Processes through Two Distinct Circuits Linked to the Lateral Striatum
Setogawa, S.; Okauchi, T.; Hu, D.; Wada, Y.; Hikishima, K.; Onoe, H.; Nishizawa, K.; Sakayori, N.; Miyawaki, H.; Kitanishi, T.; Mizuseki, K.; Cui, Y.; Kobayashi, K.
10.1101/2023.10.19.563198 — animal behavior and cognition — Posted on 2023-12-19
1599 Direct long read visualization reveals metabolic interplay between two antimalarial drug targets
Liu, S.; Ebel, E. R.; Luniewski, A.; Zulawinska, J.; Simpson, M. L.; Kim, J.; Ene, N.; Braukmann, T. W. A.; Congdon, M.; Santos, W.; Yeh, E.; Guler, J. L.
10.1101/2023.02.13.528367 — genomics — Posted on 2023-12-19
1600 Causal inference for multiple risk factors and diseases from genomics data
Machnik, N.; Mahmoudi, M.; Kraetschmer, I.; Bauer, M. J.; Robinson, M. R.
10.1101/2023.12.06.570392 — genetics — Posted on 2023-12-19
1604 Continuous endosomes form functional subdomains and orchestrate rapid membrane trafficking in trypanosomes
Link, F.; Borges, A.; Karo, O.; Jungblut, M.; Mueller, T.; Meyer-Natus, E.; Krueger, T.; Sachs, S.; Jones, N. G.; Morphew, M.; Sauer, M.; Stigloher, C.; McIntosh, J. R.; Engstler, M.
10.1101/2023.07.20.549860 — cell biology — Posted on 2023-12-19
1605 Securin Regulates the Spatiotemporal Dynamics of Separase
Turpin, C. G. S.; Sloan, D.; LaForest, M.; Klebanow, L. U.; Mitchell, D.; Severson, A. F.; Bembenek, J. N.
10.1101/2023.12.12.571338 — cell biology — Posted on 2023-12-19
1606 Detection of mitotic neuroblasts provides additional evidence of steady state neurogenesis in the adult enteric nervous system
Gorecki, A. M.; Slosberg, J.; Hong, S. M.; Migden, B.; Gulko, A.; Singh, A.; Zhang, C.; Gurumurthy, R.; Kulkarni, S.
10.1101/2022.11.14.516462 — neuroscience — Posted on 2023-12-19
1607 A Functional Schizophrenia-associated genetic variant near the TSNARE1 and ADGRB1 genes.
Wahbeh, M. H.; Boyd, R. J.; Yovo, C.; Rike, B.; McCallion, A. S.; Avramopoulos, D.
10.1101/2023.12.18.570831 — genetics — Posted on 2023-12-19
1617 An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ
Stalder, P.; Serdiuk, T.; Ghosh, D.; Fleischmann, Y.; Malinovska, L.; Davranche, A.; Haenseler, W.; Boudou, C.; Tsika, E.; Ouared, A.; Stoehr, J.; Melki, R.; Riek, R.; de Souza, N.; Picotti, P.
10.1101/2023.12.18.572111 — systems biology — Posted on 2023-12-18
1618 Methylmercury demethylation and volatilization by animals expressing microbial enzymes.
Tepper, K.; King, J.; Cholan, P. M.; Pfitzner, C.; Morsch, M.; Apte, S.; Maselko, M.
10.1101/2023.12.11.571038 — synthetic biology — Posted on 2023-12-18
1619 Cytochrome P450 CYP72A219 is Involved in Evolution of Metabolic Resistance to Tembotrione in Amaranthus palmeri Populations
Rigon, C. A. G.; Kupper, A.; Sparks, C.; Montgomery, J.; Peter, F.; Schepp, S.; Perez-Jones, A.; Tranel, P. J.; Beffa, R.; Dayan, F. E.; Gaines, T. A.
10.1101/2023.12.13.571468 — plant biology — Posted on 2023-12-18
1621 Enhanced Feature Selection for Microbiome Data using FLORAL: Scalable Log-ratio Lasso Regression
Fei, T.; Funnell, T.; Waters, N.; Raj, S. S.; Sadeghi, K.; Dai, A.; Miltiadous, O.; Shouval, R.; Lv, M.; Peled, J. U.; Ponce, D. M.; Perales, M.-A.; Gönen, M.; van den Brink, M. R. M.
10.1101/2023.05.02.538599 — bioinformatics — Posted on 2023-12-18
1623 Identification of a human hematopoietic stem cell subset that retains memory of inflammatory stress
Zeng, A. G. X.; Nagree, M. S.; Jakobsen, N. A.; Shah, S.; Murison, A.; Cheong, J.-G.; Turkalj, S.; Lim, I.; Jin, L.; Araujo, J.; Aguilar-Navarro, A. G.; Parris, D.; McLeod, J.; Kim, H.; Lee, H. S.; Zhang, L.; Boulanger, M.; Wagenblast, E.; Flores-Figueroa, E.; Wang, B.; Schwartz, G. W.; Shultz, L. D.; Josefowicz, S. Z.; Vyas, P.; Dick, J. E.; Xie, S. Z.
10.1101/2023.09.11.557271 — cell biology — Posted on 2023-12-18
1624 Metabolomics of Mouse Embryonic CSF Following Maternal Immune Activation
Petrova, B.; Lacey, T. E.; Culhane, A. J.; Cui, J.; Raskin, A.; Mishra, A.; Lehtinen, M. K.; Kanarek, N.
10.1101/2023.12.06.570507 — neuroscience — Posted on 2023-12-18
1629 Dual localization of JA receptor, CaCOI2, explains JA perception dynamics in chickpea
Singh, A. P.; Singh, E.; Singh, A. K.; Fatima, U.; Senthil-Kumar, M.; Giri, J.
10.1101/2023.12.18.572114 — plant biology — Posted on 2023-12-18
1630 The activated plant NRC4 immune receptor forms a hexameric resistosome
Liu, F.; Yang, Z.; Wang, C.; Martin, R.; Qiao, W.; Carette, J. E.; Luan, S.; Nogales, E.; Staskawicz, B.
10.1101/2023.12.18.571367 — plant biology — Posted on 2023-12-18
1631 Plasmodesmata act as unconventional membrane contact sites regulating inter-cellular molecular exchange in plants
Smokvarska, M.; Perez-Sancho, J.; Glavier, M.; Sritharan, S.; Dubois, G.; Dietrich, V.; Platre, M. P.; Li, Z. P.; Paterlini, A.; Moreau, H.; Fouillen, L.; GRISON, M. S.; Cana-Quijada, P.; Moraes, T. S.; Immel, F.; Wattelet, V.; Ducros, M.; Brocard, L.; Chambaud, C.; Zabrady, M.; Luo, Y.; Busch, W.; Tilsner, J.; Helariutta, Y.; Russinova, J.; Taly, A.; Jaillais, Y.; Bayer, E.
10.1101/2023.12.18.572149 — plant biology — Posted on 2023-12-18
1634 Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease
Khaled, M. L.; Ren, Y.; Kundalia, R.; Alhaddad, H.; Chen, Z.; Wallace, G. C.; Evernden, B.; Ospina, O. E.; Hall, M.; Liu, M.; Darville, L. N. F.; Izumi, V.; Chen, Y. A.; Pilon-Thomas, S.; Stewart, P. A.; Koomen, J. M.; Corallo, S. A.; Jain, M. D.; Robinson, T. J.; Locke, F. L.; Forsyth, P. A.; Smalley, I.
10.1101/2023.12.18.572239 — cancer biology — Posted on 2023-12-18
1635 Structures of kinetic intermediate states of HIV-1 reverse transcriptase DNA synthesis
Vergara, S.; Zhou, X.; Santiago, U.; Conway, J. F.; Sluis-Cremer, N.; Calero, G.
10.1101/2023.12.18.572243 — biophysics — Posted on 2023-12-18
1636 Engineered Protein Nanosheets for the Scale up of Mesenchymal Stem Cell Culture on Bioemulsions
Bosch-Fortea, M.; Nadal, C.; Chrysanthou, A.; Marciano, D.; Kanso, H.; Nguyen, N.; Gautrot, J.
10.1101/2023.12.18.572135 — bioengineering — Posted on 2023-12-18
1637 Unveiling Vaginal Fibrosis: A Novel Murine Model Using Bleomycin and Epithelial Disruption
McCracken, J. M.; Calderon, G. A.; Kumar, L.; Balaji, S.; Rivas, F.; Erxleben, D.; Hall, A.; Hakim, J.
10.1101/2023.12.18.572175 — physiology — Posted on 2023-12-18
1639 Re-coding of G protein-coupled receptor signaling enables emergent cellular behavior.
Dehkhoda, F.; Ringuet, M.; Whitfield, E. A.; Mutunduwe, K.; Nowell, C. J.; Misganaw, D.; Xu, Z.; Hossain, A. M.; Fothergill, L. J.; McDougall, S. J.; Furness, J. B.; Furness, S. G. B.
10.1101/2023.12.18.572241 — cell biology — Posted on 2023-12-18
1640 High order expression dependencies finely resolve cryptic states and subtypes in single cell data
Jansma, A.; Yao, Y.; Wolfe, J.; Del Debbio, L.; Beentjes, S. V.; Ponting, C. P.; Khamseh, A.
10.1101/2023.12.18.572232 — molecular biology — Posted on 2023-12-18
1641 Pathogen-microbiome interactions and the virulence of an entomopathogenic fungus
Kolp, M. R.; Acosta, Y. d. A.; Brewer, W.; Nichols, H. L.; Goldstein, E. B.; Tallapragada, K.; Parker, B. J.
10.1101/2023.12.18.572164 — microbiology — Posted on 2023-12-18
1642 Covalent Targeting of Splicing in T Cells.
Scott, K. A.; Kojima, H.; Ropek, N.; Warren, C. D.; Zhang, T. L.; Hogg, S. J.; Webster, C.; Zhang, X.; Rahman, J.; Melillo, B.; Cravatt, B. F.; Lyu, J.; Abdel-Wahab, O.; Vinogradova, E. V.
10.1101/2023.12.18.572199 — immunology — Posted on 2023-12-18
1647 The molecular basis of sugar detection by an insect taste receptor
Gomes, J. V. T.; Singh-Bhagania, S.; Cenci, M.; Cordon, C. C.; Singh, M.; Butterwick, J. A.
10.1101/2023.12.18.572227 — neuroscience — Posted on 2023-12-18
1649 DDHD2 is necessary for activity-driven fatty acid fueling of nerve terminal function
Kumar, M.; Wu, Y.; Knapp, J.; Park, D.; Gupta, K.; De Camilli, P.; Ryan, T. A.
10.1101/2023.12.18.572201 — neuroscience — Posted on 2023-12-18
1650 Light-phase prednisone promotes glucose oxidation in heart through novel transactivation targets of cardiomyocyte-specific GR and KLF15
El Abdellaoui-Soussi, F.; Durumutla, H. B.; Latimer, H.; Prabakaran, A. D.; McFarland, K.; Miz, K.; Piczer, K.; Werbrich, C.; Jain, M. K.; Haldar, S. M.; Quattrocelli, M.
10.1101/2023.12.18.572210 — physiology — Posted on 2023-12-18
1651 Optimized mucin-selective enrichment strategy to probe the mucinome
Mahoney, K. E.; Chang, V.; Lucas, T. M.; Maruszko, K.; Malaker, S. A.
10.1101/2023.12.18.572204 — biochemistry — Posted on 2023-12-18
1652 Mapping Structural and Dynamic Divergence Across the MBOAT family
Ansell, T. B.; Healy, M.; Coupland, C. E.; Sansom, M. S. P.; Siebold, C.
10.1101/2023.12.18.572254 — biochemistry — Posted on 2023-12-18
1654 An evolutionary optimum amid moderate heritability in prokaryotic cell size
Secaira-Morocho, H.; Chede, A.; Gonzalez-de-Salceda, L.; Garcia-Pichel, F.; Zhu, Q.
10.1101/2023.12.18.571935 — evolutionary biology — Posted on 2023-12-18
1658 Metaproteogenomics resolution of a high-CO2 aquifer community suggests an active symbiotic lifestyle of groundwater Gracilibacteria
Figueroa-Gonzalez, P. A.; Bornemann, T. L. V.; Hinzke, T.; Maass, S.; Trautwein-Schult, A.; Starke, J.; Moore, C. J.; Esser, S. P.; Plewka, J.; Hesse, T.; Schmidt, T. C.; Schreiber, U.; Bor, B.; Becher, D.; Probst, A. J.
10.1101/2023.12.18.572140 — ecology — Posted on 2023-12-18
1660 Global organelle profiling reveals subcellular localization and remodeling at proteome scale
Hein, M. Y.; Peng, D.; Todorova, V.; McCarthy, F.; Kim, K.; Liu, C.; Savy, L.; Januel, C.; Baltazar-Nunez, R.; Bax, S.; Vaid, S.; Vangipuram, M.; Ivanov, I. E.; Byrum, J. R.; Pradeep, S.; Gonzalez, C. G.; Aniseia, Y.; Wang, E.; Creery, J. S.; McMorrow, A. H.; Burgess, J.; Sunshine, S.; Yeung-Levy, S.; DeFelice, B. C.; Mehta, S. B.; Itzhak, D. N.; Elias, J. E.; Leonetti, M. D.
10.1101/2023.12.18.572249 — cell biology — Posted on 2023-12-18
1661 Human Induced Pluripotent Stem Cell based Hepatic-Modeling of Lipid metabolism associated TM6SF2 E167K variant
Faccioli, L. A. P.; Sun, Y.; Motomura, T.; Liu, Z.; Kurihara, T.; Hu, Z.; Cetin, Z.; Franks, J.; Stolz, D.; Ostrowska, A.; Florentino, R. M.; Fox, I. J.; Soto-Gutierrez, A.
10.1101/2023.12.18.572248 — cell biology — Posted on 2023-12-18
1664 Chlamydiae as symbionts of photosynthetic dinoflagellates
Maire, J.; Collingro, A.; Tandon, K.; Jameson, V. J.; Judd, L. M.; Horn, M.; Blackall, L. L.; van Oppen, M. J. H.
10.1101/2023.12.18.572253 — microbiology — Posted on 2023-12-18
1665 Toxoplasma gondii F-Box Protein L2 Silences Feline-Restricted Genes Necessary for Sexual Commitment
Baptista, C. G.; Hosking, S.; Gas-Pascual, E.; Ciampossine, L.; Abel, S.; Hakimi, M.-A.; Jeffers, V.; Le Roch, K. G.; West, C. M.; Blader, I.
10.1101/2023.12.18.572150 — microbiology — Posted on 2023-12-18
1666 Unveiling the Immune Dynamics of Neisseria Persistent Oral Colonization: A Roadmap for Innovative Vaccine Strategies
Alles, M.; Gunasena, M.; Zia, T.; D'Mello, A.; Saroj Bhattarai, S.; Mulhern, W.; Terry, L.; Scherger, T.; Wijeratne, S.; Singh, S.; Wijeratne, A.; Kasturiratna, D.; Tettelin, H.; Weyand, N. J.; Liyanage, N.
10.1101/2023.12.18.572139 — immunology — Posted on 2023-12-18
1667 Amyloid precursor protein induces reactive astrogliosis
Velezmoro, G.; Vukic, D.; Onyango, I.; Arias, C.; Novotny, J. S.; Texlova, K.; Wang, S.; Kovacovicova, K. L.; Polakova, N.; Zelinkova, J.; Carna, M.; Strasil, V. L.; Head, B.; Havas, D.; Mistrik, M.; Zorec, R.; Verkhratsky, A.; Keegan, L. P.; OConnel, M. A.; Rissman, R. A.; Stokin, G. B.
10.1101/2023.12.18.571817 — neuroscience — Posted on 2023-12-18
1668 Effects of aging on glucose and lipid metabolism in mice
Lien, E. C.; Vu, N.; Westermark, A. M.; Danai, L. V.; Lau, A. N.; Gultekin, Y.; Kukurugya, M. A.; Bennett, B. D.; Vander Heiden, M.
10.1101/2023.12.17.572088 — physiology — Posted on 2023-12-18
1669 Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis
Bannoura, S. F.; Aboukameel, A.; Khan, H. Y.; Uddin, M. H.; Beal, E.; Wagner, K.-U.; Mohammad, R.; Al Hallak, M. N.; Pasche, B.; Azmi, A. S.
10.1101/2023.12.18.572102 — cancer biology — Posted on 2023-12-18
1670 HLA-EpiCheck: A B-cell epitope prediction tool for HLA proteins using molecular dynamics simulation data.
Amaya-Ramirez, D.; Devriese, M.; Lhotte, R.; Usureau, C.; Smail-Tabbone, M.; Taupin, J.-L.; Devignes, M.-D.
10.1101/2023.12.18.572133 — bioinformatics — Posted on 2023-12-18
1672 Bile is a route of excretion for homogentisic acid in alkaptonuria
Norman, B. P.; Sutherland, H.; Wilson, P. J.; Rutland, D. A.; Milan, A. M.; Hughes, A. T.; Davison, A. S.; Khedr, M.; Jarvis, J. C.; Gallagher, J. A.; Bou-Gharios, G.; Ranganath, L. R.
10.1101/2023.12.18.572165 — biochemistry — Posted on 2023-12-18
1673 Estimation of effective population size and effective number of breeders in an abundant and heavily exploited marine teleost
Bertram, A. B.; Bell, J.; Brauer, C. B.; Fairclough, D.; Hammer, P.; Sandoval-Castillo, J. B.; Wellenreuther, M.; Beheregaray, L. B.
10.1101/2023.12.17.572092 — genomics — Posted on 2023-12-18
1675 A genome and tissue-specific transcriptomes of the large-polyp coral, Fimbriaphyllia (Euphyllia) ancora: Recipe for a coral polyp
Shikina, S.; Yoshioka, Y.; Chiu, Y.-L.; Uchida, T.; Chen, E.; Cheng, Y.-C.; Lin, T.-C.; Chu, Y.-L.; Kanda, M.; Kawamitsu, M.; Fujie, M.; Takeuchi, T.; Zayasu, Y.; Satoh, N.; Shinzato, C.
10.1101/2023.12.17.572093 — genomics — Posted on 2023-12-18
1677 Atlas of telomeric repeat diversity in Arabidopsis thaliana
Tao, Y.; Xian, W.; Rabanal, F.; Movilli, A.; Lanz, C.; Shirsekar, G.; Weigel, D.
10.1101/2023.12.18.572118 — genomics — Posted on 2023-12-18
1679 The genome of the rayed Mediterranean limpet Patella caerulea (Linnaeus, 1758)
Halstead-Nussloch, G.; Signorini, S. G.; Giulio, M.; Crocetta, F.; Munari, M.; Della Torre, C.; Weber, A. A.-T.
10.1101/2023.12.18.572124 — genomics — Posted on 2023-12-18
1681 Modulation of neural gene networks by estradiol in old rhesus macaque females.
Cervera-Juanes, R.; Zimmerman, K. D.; Wilhelm, L.; Zhu, D.; Bodie, J.; Kohama, S. G.; Urbanski, H.
10.1101/2023.12.18.572105 — genetics — Posted on 2023-12-18
1682 The germline regulates longevity and somatic repair in a sex-specific manner
Moses, E.; Atlan, T.; Sun, X.; Franek, R.; Siddiqui, A.; Marinov, G. K.; Shifman, S.; Zucker, D. M.; Oron-Gottesman, A.; Greenleaf, W. J.; Cohen, E.; Ram, O.; Harel, I.
10.1101/2023.12.18.572041 — genetics — Posted on 2023-12-18
1689 Conserved and derived expression patterns and positive selection on dental genes reveal complex evolutionary context of ever-growing rodent molars
Calamari, Z. T.; Song, A.; Cohen, E.; Akter, M.; Roy, R. D.; Hallikas, O.; Christensen, M. M.; Li, P.; Marangoni, P.; Jernvall, J.; Klein, O. D.
10.1101/2023.12.18.572015 — evolutionary biology — Posted on 2023-12-18
1690 The diallelic self-incompatibility system in Oleaceae is controlled by a hemizygous genomic region expressing a gibberellin pathway gene
Castric, V.; Batista, R. A.; Carre, A.; Mousavi, S.; mazoyer, c.; Gode, C.; Gallina, S.; Ponitzki, C.; Theron, A.; bellec, a.; marande, w.; Santoni, S.; mariotti, r.; rubini, a.; Legrand, S.; Billiard, S.; Vekemans, X.; vernet, p.; Saumitou-Laprade, P.
10.1101/2023.12.18.571976 — evolutionary biology — Posted on 2023-12-18
1692 Structure and mechanism of Zorya anti-phage defense system
Hu, H.; Hughes, T. C. D.; Popp, P. F.; Roa-Eguiara, A.; Martin, F. J. O.; Rutbeek, N. R.; Hendriks, I. A.; Payne, L. J.; Yan, Y.; Sousa, V. K. d.; Wang, Y.; Nielsen, M. L.; Berry, R. M.; Erhardt, M.; Jackson, S. A.; Taylor, N. M. I.
10.1101/2023.12.18.572097 — molecular biology — Posted on 2023-12-18
1694 Climatic limits to Atlantic salmon population fitness at continental scales
Morris, O. F.; Baroarson, H.; Gonzalez Ferreras, A.; Lauridsen, R.; Pawar, S.; Rosindell, J.; Woodward, G.
10.1101/2023.12.18.571080 — ecology — Posted on 2023-12-18
1699 Unbiased Complete Estimation of Chloroplast Number in Plant Cells Using Deep Learning Methods
Su, Q.; Liu, L.; Hu, Z.; Wang, T.; Wang, H.; Guo, Q.; Liao, X.; Dong, Z.; Yang, S.; Liu, N.; Zhao, Q.
10.1101/2023.12.17.572064 — cell biology — Posted on 2023-12-18
1700 Persistent enrichment of multidrug resistant Klebsiella in oral and nasal communities during long-term starvation
Liu, J.; Spencer, N.; Utter, D. R.; Grossman, A.; Santos, N. C. D.; Shi, W.; Baker, J. L.; Hasturk, H.; He, X.; Bor, B.
10.1101/2023.12.18.572173 — microbiology — Posted on 2023-12-18
1702 Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechanotransduction
Moraes de Lima Perini, M.; Pugh, J. N.; Scott, E. M.; Bhula, K.; Chirgwin, A. C.; Reul, O. N.; Berbari, N. F.; Li, J.
10.1101/2023.12.15.570609 — cell biology — Posted on 2023-12-18
1704 Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells
Koike, S.; Tachikawa, M.; Tsutsumi, M.; Okada, T.; Nemoto, T.; Keino-Masu, K.; Masu, M.
10.1101/2023.12.17.572077 — cell biology — Posted on 2023-12-18
1705 Cryptosporidium Life Cycle Small Molecule Probing Implicates Translational Repression And An Apetala 2 Transcription Factor In Sexual Differentiation
Hasan, M. M.; Mattice, E. B.; Teixeira, J. E.; Jumani, R. S.; Stebbins, E. E.; Klopfer, C. E.; Franco, S. E.; Love, M. S.; McNamara, C. W.; Huston, C. D.
10.1101/2023.12.18.572108 — microbiology — Posted on 2023-12-18
1706 Sequential genetic, epigenetic alterations in human pluripotent stem cells for recurrent abnormality
Kim, Y.-J.; Kang, B.; Kweon, S.; Oh, S.; Kim, D.; Gil, D.; Lee, H.; Kim, J.; Ju, J. H.; Roh, T.-Y.; Hong, C. P.; Cha, H.-J.
10.1101/2023.12.17.572095 — cell biology — Posted on 2023-12-18
1707 PUPpy: a primer design pipeline for substrain-level microbial detection and absolute quantification.
Ghezzi, H.; Fan, M. Y.; Ng, K. M.; Burckhardt, J. C.; Pepin, D. M.; Lin, X.; Ziels, R. M.; Tropini, C.
10.1101/2023.12.18.572184 — microbiology — Posted on 2023-12-18
1708 Dynamics and plasticity of stem cells in the regenerating human colonic epithelium
Oost, K. C.; Kahnwald, M.; Barbiero, S.; de Medeiros, G. Q. G.; Suppinger, S.; Kalck, V.; Challet Meylan, L.; Smallwood, S. A.; Stadler, M. B.; Liberali, P.
10.1101/2023.12.18.572103 — cell biology — Posted on 2023-12-18
1710 Quantifying stem cell derived islet graft volume and composition with FDOPA positron emission tomography
Lithovius, V.; Lahdenpohja, S.; Ibrahim, H.; Saarimäki-Vire, J.; Uusitalo, L.; Montaser, H.; Mikkola, K.; Yim, C.-B.; Keller, T.; Rajander, J.; Balboa, D.; Barsby, T.; Solin, O.; Nuutila, P.; Grönroos, T. J.; Otonkoski, T.
10.1101/2023.12.18.572141 — cell biology — Posted on 2023-12-18
1712 Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1
Froehlich, T.; Jenner, A.; Cavarischia-Rega, C.; Fagbadebo, F. O.; Lurz, Y.; Frecot, D. I.; Kaiser, P. D.; Nueske, S.; Scholz, A.; Schaeffer, E.; Garcia-Saez, A. J.; Macek, B.; Rothbauer, U.
10.1101/2023.12.18.572153 — cell biology — Posted on 2023-12-18
1713 Camel milk affects serum metabolites by modulating the intestinal microflora
Yue, H.; Zhang, J.; Wang, R.; Zhao, L.; Kou, Y.; Li, R.; Yang, Z.; Qian, Y.; Li, X.; Wang, X.; Yasheng, P.; Wu, J.; Xing, X.; Xie, L.; Niu, H.; Chen, G.; Yang, J.; Liu, Y.; Shi, T.; Gao, F.
10.1101/2023.12.18.572112 — microbiology — Posted on 2023-12-18
1714 Mitochondrial thermogenesis regulates heat-shock response in the nucleus
Lee, H. Y.; Kim, H.-R.; Kwak, C.; Kang, M.-G.; Roe, J.-S.; Rhee, H.-W.
10.1101/2023.12.18.571173 — cell biology — Posted on 2023-12-18
1715 Gut microbiota DPP4-like enzymes are increased in type-2 diabetes and contribute to incretin inactivation
Olivares, M.; Hernandez-Calderon, P.; Cardenas-Brito, S.; Liebana-Garcia, R.; Sanz, Y.; Benitez-Paez, A.
10.1101/2023.12.18.572132 — microbiology — Posted on 2023-12-18
1716 VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
Ugur, B.; Schueder, F.; Shin, J.; Hanna, M. G.; Wu, Y.; Leonzino, M.; Su, M.; McAdow, A. R.; Wilson, C. A.; Postlethwait, J.; Solnica-Krezel, L.; Bewersdorf, J.; De Camilli, P.
10.1101/2023.12.18.572081 — cell biology — Posted on 2023-12-18
1717 Extracellular vesicles propagate aging in COPD airway epithelial cells by transfer of microRNA-34a
Devulder, J. V.; Baker, J. R.; Fenwick, P. S.; Odqvist, L.; Donnelly, L. E.; Barnes, P. J.
10.1101/2023.12.18.572220 — cell biology — Posted on 2023-12-18
1719 A Blood Immunological Signature of Subclinical Coronary Artery Atherosclerosis in People Living with HIV-1 Receiving Antiretroviral Therapy
Wiche Salinas, T. R.; Zhang, Y.; Gosselin, A.; Fonseca Do Rosario, N.; El-Far, M.; Filali-Mouhim, A.; Routy, J.-P.; Chartrand-Lefebvre, C.; Landay, A. L.; Durand, M.; Tremblay, C.; Ancuta, P.
10.1101/2023.12.15.571922 — immunology — Posted on 2023-12-18
1720 Assessing Immune Factors in Maternal Milk and Paired Infant Plasma Antibody Binding to Human Rhinoviruses
Vera, J. M.; McIlwain, S. J.; Fye, S.; Palmenberg, A.; Bochkov, Y. A.; Li, H.; Pinapati, R.; Tan, J.; Gern, J.; Seroogy, C. M.; Ong, I. M.
10.1101/2023.12.17.565204 — immunology — Posted on 2023-12-18
1721 Chemotherapy synergizes with cancer vaccines and expands stem-like TCF1+CD8+ T cells
Noblecourt, L.; Wicki, A.; Pereira-Almeida, V.; McAuliffe, J.; Steffke, E.; Panetti, S.; Ramirez-Valdez, R. A.; Chandrasekar, V.; Jainarayanan, A.; Hill, A. V.; Van den Eynde, B. J.; Leung, C. S. K.
10.1101/2023.12.18.572068 — immunology — Posted on 2023-12-18
1722 Single voxel autocorrelation reflects hippocampal function in temporal lobe epilepsy
Bouffard, N. R.; Audrain, S.; Golestani, A. M.; Barense, M. D.; Moscovitch, M.; McAndrews, M. P.
10.1101/2023.12.15.571916 — neuroscience — Posted on 2023-12-18
1723 The effect of long-term sleep disruption on the brain - looking beyond amyloid
Mentink, L. J.; van Osch, M. J.; Bakker, L. J.; Olde Rikkert, M. G.; Beckmann, C. F.; Claassen, J. A.; Haak, K. V.
10.1101/2023.12.15.571841 — neuroscience — Posted on 2023-12-18
1725 A pilot study of the impact of smells on the behavior of level 3 autistic children and adolescents during an ongoing task
Dantec, M.; Cazalis, F.; Peyrical, A.; Luisier, A.-C.; Benabou, C.; Coeur-Bizot, S.; Mandairon, N.; Mantel, M.; Bensafi, M.
10.1101/2023.12.15.571849 — neuroscience — Posted on 2023-12-18
1727 Reduced Lateralization of Multiple Functional Brain Networks in Autistic Males
Peterson, M.; Prigge, M. B. D.; Floris, D. L.; Bigler, E. D.; Zielinski, B.; King, J. B.; Lange, N.; Alexander, A. L.; Lainhart, J. E.; Nielsen, J. A.
10.1101/2023.12.15.571928 — neuroscience — Posted on 2023-12-18
1728 Fluvoxamine maleate ameliorates Alzheimer disease pathology by mitigating amyloid-beta load and neuroinflammation in 5XFAD mice
Kaur, S.; Sharma, K.; Sharma, A.; Sandha, K. K.; Ali, S. M.; Ahmed, R.; Ramajayan, P.; Singh, P. P.; Ahmed, Z.; Kumar, A.
10.1101/2023.12.17.572086 — neuroscience — Posted on 2023-12-18
1729 Within-Individual Organization of the Human Cognitive Cerebellum: Evidence for Closely Juxtaposed, Functionally Specialized Regions
Saadon-Grosman, N.; Du, J.; Kosakowski, H. L.; Angeli, P. A.; DiNicola, L. M.; Eldaief, M. C.; Buckner, R. L.
10.1101/2023.12.18.572062 — neuroscience — Posted on 2023-12-18
1732 Ca2+ Oscillation in Vascular Smooth Muscle Cells Control Myogenic Spontaneous Vasomotion and Counteract Post-ischemic No-reflow
Li, J.; Zhang, Y.; Zhang, D.; Wang, W.; Xie, H.; Ruan, J.; Jin, Y.; Li, T.; Li, X.; Zhao, B.; Zhang, X.; Lin, J.; Shi, H.; Jia, J.-M.
10.1101/2023.12.17.572091 — neuroscience — Posted on 2023-12-18
1735 SleepEEGpy: a Python-based package for the preprocessing, analysis, and visualization of sleep EEG data
Belonosov, G.; Falach, R.; Schmidig, F. J.; Aderka, M.; Zhelezniakov, V.; Shani-Hershkovich, R.; Bar, E.; Nir, Y.
10.1101/2023.12.17.572046 — neuroscience — Posted on 2023-12-18
1739 Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis
Zheng, C.; Herve, B.; Meijer, M.; Rubio Rodriguez-Kirby, L. A.; Guerreiro Cacais, A. O.; Kukanja, P.; Kabbe, M.; Olsson, T.; Agirre, E.; Castelo-Branco, G.
10.1101/2023.12.18.572120 — neuroscience — Posted on 2023-12-18
1743 Transcriptional signatures of fentanyl use in the mouse ventral tegmental area
Fox, M. E.; Montemarano, A.; Ostman, A. E.; Basu, M.; Herb, B.; Ament, S. A.; Fox, L. D.
10.1101/2023.12.18.572172 — neuroscience — Posted on 2023-12-18
1745 Inhibition of MMP 2 protects the endothelial glycocalyx and improves diastolic function in diabetic cardiomyopathy
Buffonge, S.; Qiu, Y.; Fawaz, S.; Gamez, M.; Crompton, M.; Butler, M. J.; Welsh, G. I.; Madeddu, P.; Foster, R. R.; Satchell, S. C.
10.1101/2023.12.18.572183 — physiology — Posted on 2023-12-18
1746 Ferritinophagy is a Druggable Vulnerability of Quiescent Leukemic Stem Cells
Larrue, C.; Mouche, S.; Angelino, P.; Sajot, M.; Birsen, R.; Vergez, F.; Recher, C.; Mansat-De Mas, V.; Gu, Q.; Xu, J.; Tsantoulis, P.; Sarry, J.-E.; Tamburini, J.
10.1101/2023.12.18.572101 — cancer biology — Posted on 2023-12-18
1747 Distinct host preconditioning regimens differentially impact the antitumor potency of adoptively transferred Th17 cells.
Wittling, M. C.; Knochelmann, H. M.; Wyatt, M. M.; Rangel Rivera, G. O.; Cole, A. C.; Lesinski, G. B.; Paulos, C. M.
10.1101/2023.12.18.572179 — cancer biology — Posted on 2023-12-18
1749 Active membrane deformations of a minimal synthetic cell
Sciortino, A.; Faizi, H.; Uplap, S.; Frechette, L.; Peterson, M. S.; Vlahovska, P.; Baskaran, A.; Hagan, M. F.; Bausch, A.
10.1101/2023.12.18.571643 — biophysics — Posted on 2023-12-18
1750 RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds
Fu, B.; Brock, E. E.; Breiter, J. C.; Tian, R.; Andrews, R.; Toomey, C. E.; Lachica, J.; Lashley, T.; Ryten, M.; Wood, N. W.; Vendruscolo, M.; Gandhi, S.; Weiss, L. E.; Beckwith, J. S.; Lee, S. F.
10.1101/2023.12.18.572148 — biophysics — Posted on 2023-12-18
1751 COMPUTATIONAL IDENTIFICATION OF ANTIBODY-BINDING EPITOPES FROM MIMOTOPE DATASETS
Li, R.; Wilderotter, S.; Stoddard, M.; Van Egeren, D.; Chakravarty, A.; Joseph-McCarthy, D.
10.1101/2023.12.17.572067 — bioinformatics — Posted on 2023-12-18
1755 A cascade of sulfur transferases delivers sulfur to the sulfur-oxidizing heterodisulfide reductase-like complex
Tanabe, T. S.; Bach, E.; D'Ermo, G.; Mohr, M. G.; Hager, N.; Pfeiffer, N.; Guiral, M.; Dahl, C.
10.1101/2023.12.18.572138 — biochemistry — Posted on 2023-12-18
1756 Beyond the VSG Layer: Exploring the Role of Intrinsic Disorder in the Invariant Surface Glycoproteins of African Trypanosomes
Sulzen, H.; Volkov, A. N.; Geens, R.; Zahedifard, F.; Stijlemans, B.; Zoltner, M.; Magez, S.; Sterckx, Y. G.-J.; Zoll, S.
10.1101/2023.12.18.572128 — biochemistry — Posted on 2023-12-18
1759 Panpipes: a pipeline for multiomic single-cell and spatial transcriptomic data analysis
Curion, F.; Rich-Griffin, C.; Agarwal, D.; Ouologuem, S.; Thomas, T.; Theis, F. J.; Dendrou, C.
10.1101/2023.03.11.532085 — bioinformatics — Posted on 2023-12-18
1760 Endogenous oscillatory rhythms and interactive contingencies jointly influence infant attention during early infant-caregiver interaction
Phillips, E. A. M.; Goupil, L.; Csolsim, F.; Whitehorn, M.; Kaur, N.; Bruce-Gardyne, E.; Greenwood, E.; Marriott Haresign, I.; Wass, S.
10.1101/2023.06.19.545295 — neuroscience — Posted on 2023-12-18
1762 Evolving spike-protein N-glycosylation in SARS-CoV-2 variants
Baboo, S.; Diedrich, J. K.; Torres, J. L.; Copps, J.; Singh, B.; Garrett, P. T.; Ward, A. B.; Paulson, J. C.; Yates, J. R.
10.1101/2023.05.08.539897 — biochemistry — Posted on 2023-12-18
1763 Can a flower color ancestral polymorphism transcend speciation?
Sanchez-Cabrera, M.; Narbona, E.; Arista, M.; Ortiz, P. L.; Jimenez-Lopez, F. J.; Fuller, A.; Carter, B.; Whittall, J.
10.1101/2023.11.14.566988 — evolutionary biology — Posted on 2023-12-18
1764 Evaluating key evidence and formulating regulatory alternatives regarding the UK Hunting Trophies (Import Prohibition) Bill
Challender, D.; 't Sas-Rolfes, M.; Dickman, A.; Hare, D.; Hart, A.; Hoffmann, M.; Mallon, D.; Mandisodza-Chikerema, R.; Roe, D.
10.1101/2023.06.13.544826 — ecology — Posted on 2023-12-18
1765 Landscape drives zoonotic malaria prevalence in non-human primates
Johnson, E.; Sunil Kumar Sharma, R.; Ruiz Cuenca, P.; Byrne, I.; Salgado-Lynn, M.; Suraya Shahar, Z.; Col Lin, L.; Zulkifli, N.; Dilaila Mohd Saidi, N.; Drakeley, C.; Matthiopoulos, J.; Nelli, L.; Fornace, K.
10.1101/2022.06.17.496284 — ecology — Posted on 2023-12-18
1767 Pigmentation level of human iPSC-derived retinal pigment epithelium cell does not indicate a specific gene expression profile
Nakai-Futatsugi, Y.; Jin, J.; Ogawa, T.; Sakai, N.; Maeda, A.; Hironaka, K.-i.; Fukuda, M.; Danno, H.; Tanaka, Y.; Hori, S.; Shiroguchi, K.; Takahashi, M.
10.1101/2023.09.29.560095 — cell biology — Posted on 2023-12-18
1769 TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning
de Calbiac, H.; Montealegre, S.; Straube, M.; Renault, S.; Debruge, H.; Chentout, L.; Ciura, S.; Imbard, A.; Le Guillou, E.; Marian, A.; Goudin, N.; Caccavelli, L.; Fabrega, S.; Hubas, A.; van Endert, P.; Dupont, N.; Diana, J.; Kabashi, E.; de Lonlay, P.
10.1101/2023.03.29.534583 — cell biology — Posted on 2023-12-18
1772 The 3D ultrastructural morphology of a marine ammonia-oxidizing archaeon
Zhou, Y.; Yan, A.; Yang, J.; He, W.; Guo, S.; Li, Y.; Dai, Y.; Pan, X.; Cui, D.; Teng, W.; Pereira, O.; Bi, R.; Chen, S.; Fan, L.; Wang, P.; Liao, Y.; Qin, W.; Sui, S.-F.; Zhu, Y.; Zhang, C.; Liu, Z.
10.1101/2023.12.12.571259 — microbiology — Posted on 2023-12-18
1774 Modelling cognitive outcomes in the UK Biobank: education, noradrenaline and frontoparietal networks
Bravo-Merodio, L.; Williams, J. A.; Russ, D. R.; Gkoutos, G.; Brosnan, M.; Bellgrove, M. A.; Chechlacz, M.
10.1101/2023.08.31.555645 — neuroscience — Posted on 2023-12-18
1775 A system of feed-forward cerebellar circuits that extend and diversify sensory signaling
Hariani, H. N.; Algstam, A. B.; Candler, C. T.; Witteveen, I. F.; Sidhu, J. K.; Balmer, T. S.
10.1101/2023.04.11.536335 — neuroscience — Posted on 2023-12-18
1778 Activation of plant immunity through conversion of a helper NLR homodimer into a resistosome
Selvaraj, M.; Toghani, A.; Pai, H.; Sugihara, Y.; Kourelis, J.; Yuen, E. L. H.; Ibrahim, T.; Zhao, H.; Xie, R.; Maqbool, A.; De la Concepcion, J. C.; Banfield, M. J.; Derevnina, L.; Petre, B.; Lawson, D. M.; Bozkurt, T. O.; Wu, C.-H.; Kamoun, S.; Contreras, M. P.
10.1101/2023.12.17.572070 — plant biology — Posted on 2023-12-18
1780 Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis
Vannan, A.; Lyu, R.; Williams, A. L.; Negretti, N. M.; Mee, E. D.; Hirsh, J.; Hirsh, S.; Nichols, D. S.; Calvi, C. L.; Talor, C. J.; Polosukhin, V. V.; Serezani, A. P.; McCall, A. S.; Gokey, J. J.; Shim, H.; Ware, L. B.; Bacchetta, M. J.; Shaver, C. M.; Blackwell, T. S.; Walia, R.; Sucre, J. M.; Kropski, J. A.; McCarthy, D. J.; Banovich, N. E.
10.1101/2023.12.15.571954 — genomics — Posted on 2023-12-17
1782 Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis
Denner, A.; Steger, J.; Ries, A.; Morozova-Link, E.; Ritter, J.; Haas, F.; Cole, A. G.; Technau, U.
10.1101/2023.12.07.570436 — developmental biology — Posted on 2023-12-17
1786 Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin
Jiang, W. I.; Belly, H. D.; Wang, B. K.; Wong, A.; Kim, M.; Oh, F.; DeGeorge, J.; Huang, X.; Guang, S.; Weiner, O. K.; Ma, D. K.
10.1101/2023.07.25.550452 — physiology — Posted on 2023-12-17
1790 Macrophages control pathological interferon responses during viral respiratory infection
Hoagland, D. A.; Rodriguez-Morales, P.; Mann, A. O.; Yu, S.; Lai, A.; Baez Vazquez, A.; Pope, S. D.; Lim, J.; Li, S.; Zhang, X.; Li, M. O.; Medzhitov, R.; Franklin, R. A.
10.1101/2023.12.16.572019 — immunology — Posted on 2023-12-17
1791 "Cortical Delta" In The Medulla Of Sleeping Infant Rats
Ahmad, M.; Kim, J.; Dwyer, B.; Sokoloff, G.; Blumberg, M. S.
10.1101/2023.12.16.572000 — neuroscience — Posted on 2023-12-17
1794 Development of primary osteoarthritis during aging in genetically diverse UM-HET3 mice
Poudel, S. B.; Raff, R. R.; Yildirim, G.; Miller, R.; Harrison, D.; Strong, R.; Kirsch, T.; Yakar, S.
10.1101/2023.12.16.571693 — pathology — Posted on 2023-12-17
1795 An ovine model for investigation of the microenvironment of the male mammary gland
Davies, B. P.; Crew, R. C.; Cochrane, A. L. K.; Davies, K.; Baptista, A. F.; Jeckel, S.; McCrone, I.; Niu, Y.; Strugnell, B. W.; Waine, K.; Fowden, A. L.; Bryant, C. E.; Wills, J. W.; Giussani, D. A.; Hughes, K.
10.1101/2023.12.17.572059 — pathology — Posted on 2023-12-17
1796 Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography
Greenwood, H. E.; Edwards, R. S.; Tyrrell, W. E.; Barber, A. R.; Baark, F.; Tanc, M.; Khalil, E.; Falzone, A.; Ward, N. P.; DeBlasi, J. M.; Torrente, L.; Pearce, D. R.; Firth, G.; Smith, L. M.; Vilhelmsson Timmermand, O.; Huebner, A.; George, M. E.; Swanton, C.; Hynds, R. E.; DeNicola, G. M.; Witney, T. H.
10.1101/2023.12.16.572007 — cancer biology — Posted on 2023-12-17
1797 A Mechanistic Model for the Release of Ceramide from the CERT START Domain
Moqadam, M.; Gartan, P.; Talandashti, R.; Chiapparino, A.; Titeca, K.; Gavin, A.-C.; Reuter, N.
10.1101/2023.12.16.571968 — biophysics — Posted on 2023-12-17
1798 Open Soil Spectral Library (OSSL): Building reproducible soil calibration models through open development and community engagement
Safanelli, J. L.; Hengl, T.; Parente, L. L.; Minarik, R.; Bloom, D. E.; Todd-Brown, K.; Gholizadeh, A.; Mendes, W. d. S.; Sanderman, J.
10.1101/2023.12.16.572011 — bioinformatics — Posted on 2023-12-17
1799 Fully flexible molecular alignment enables accurate ligand structure modelling
Wang, Z.; Zhou, F.; Wang, Z.; Li, Y.-Q.; Wang, S.; Zheng, L.; Li, W.; Peng, X.
10.1101/2023.12.17.572051 — bioinformatics — Posted on 2023-12-17
1802 Identifying patterns to uncover the importance of biological pathways on known drug repurposing scenarios
Otero-Carrasco, B.; Ugarte Carro, E.; Prieto-Santamaria, L.; Diaz Uzquiano, M.; Caraca-Valente Hernandez, J. P.; Rodriguez-Gonzalez, A.
10.1101/2023.12.17.572035 — bioinformatics — Posted on 2023-12-17
1803 Site Effects in Multisite Fetal Brain MRI: Morphological Insights into Early Brain Development
Xu, X.; Sun, C.; Yu, H.; Yan, G.; Zhu, Q.; Kong, X.; Pan, Y.; Xu, H.; Zheng, T.; Zhou, C.; Wang, Y.; Xiao, J.; Chen, R.; Li, M.; Zhang, S.; Hu, H.; Zou, Y.; Wang, J.; Wang, G.; Wu, D.
10.1101/2023.12.16.572004 — bioengineering — Posted on 2023-12-17
1804 The α/β hydrolase domain-containing protein 1 (ABHD1) acts as a lysolipid lipase and is involved in lipid droplet formation
Torres Romero, I.; Legeret, B.; Huleux, M.; Sorigue, D.; Damm, A.; Cuine, S.; Veillet, F.; Blot, C.; Brugiere, S.; Coute, Y.; Garneau, M. G.; Kotapati, H.; Xin, Y.; Xu, J.; Bates, P. D.; THIAM, A. R.; Beisson, F.; Li-Beisson, Y.
10.1101/2023.12.17.572040 — biochemistry — Posted on 2023-12-17
1806 Assessing the impact of post-mortem damage and contamination on imputation performance in ancient DNA
Garrido Marques, A.; Rubinacci, S.; Malaspinas, A.-S.; Delaneau, O.; Sousa da Mota, B.
10.1101/2023.12.17.572049 — genomics — Posted on 2023-12-17
1809 Homeostatic mitophagy scales mitochondrial networks
Thomas, R. L.; Bishop, B. C.; Andre, L.; Nolte, H.; Graef, M.
10.1101/2023.12.17.572060 — cell biology — Posted on 2023-12-17
1810 Transgenerational effects of early life stress on the fecal microbiota in mice
Otaru, N.; Kourouma, L.; Pugin, B.; Constancias, F.; Braegger, C.; Mansuy, I. M.; Lacroix, C.
10.1101/2023.12.17.572037 — microbiology — Posted on 2023-12-17
1814 Molecular Disambiguation of Heart Rate Control by the Nucleus Ambiguus
Jalil, M.; Coverdell, T. C.; Gutierrez, V. A.; Crook, M. E.; Shi, J.; Stornetta, D. S.; Schwalbe, D. C.; Abbott, S. B. G.; Campbell, J. N.
10.1101/2023.12.16.571991 — neuroscience — Posted on 2023-12-17
1816 Estradiol regulates local synthesis of synaptic proteome via sex-specific mechanisms.
Raval, P.; Rae, H.; Duarte, R. R.; Watson, I. A.; Sellers, K.; Pachon, K. M.; Sichlinger, L.; Powell, T. R.; Yasvoina, M. V.; Mukherjee, J.; Moss, S. J.; Brandon, N. J.; Srivastava, D. P.
10.1101/2023.12.17.571898 — neuroscience — Posted on 2023-12-17
1820 Architecture of Ca2+ tunneling, a basic Ca2+ signaling modality important for secretion
Courjaret, R.; Wagner, L. E.; Ammouri, R. R.; Assaf, L.; Yu, F.; Fisher, M.; Terasaki, M.; Yule, D. I.; Machaca, K.
10.1101/2023.12.17.572039 — cell biology — Posted on 2023-12-17
1822 scPharm: identifying pharmacological subpopulations of single cells for precision medicine in cancers
Tian, P.; Zheng, J.; Xu, Y.; Wu, T.; Chen, S.; Zhang, Y.; Zhang, B.; Qiao, K.; Fan, Y.; Ambrogio, C.; Wang, H.
10.1101/2023.12.11.571182 — bioinformatics — Posted on 2023-12-17
1824 Genetic consequences of improved river connectivity in brown trout (Salmo trutta, L.)
Moccetti, P.; Dodd, J. R.; Joyce, D. A.; Nunn, A. D.; Gillespie, B.; Bolland, J. D.
10.1101/2023.07.30.551162 — evolutionary biology — Posted on 2023-12-17
1825 A stable microtubule bundle formed through an orchestrated multistep process controls quiescence exit
Laporte, D.; Massoni-Laporte, A.; Lefranc, C.; Dompierre, J.; Mauboules, D.; Nsamba, E. T.; Royou, A.; Gal, L.; Schuldiner, M.; Gupta, M.; Sagot, I.
10.1101/2023.05.02.539064 — cell biology — Posted on 2023-12-17
1826 Simultaneous PET and molecular MR imaging of cardiopulmonary fibrosis in a mouse model of left ventricular dysfunction
Moon, B. F.; Zhou, I. Y.; Ning, Y.; Chen, Y. I.; Le Fur, M.; Shuvaev, S.; Akam, E. A.; Ma, H.; Molinos Solsona, C.; Weigand-Whittier, J.; Rotile, N.; Hariri, L. P.; Drummond, M.; Boice, A. T.; Zygmont, S. E.; Sharma, Y.; Warburton, R.; Martin, G.; Blanton, R. M.; Fanburg, B. L.; Hill, N. S.; Caravan, P.; Penumatsa, K. C.
10.1101/2023.12.15.571959 — molecular biology — Posted on 2023-12-17
1830 A calibration protocol for soil-crop models
Wallach, D.; Buis, S.; Seserman, D.-M.; Palosuo, T.; Thorburn, P.; Mielenz, H.; Justes, E.; Kersebaum, K.-C.; Dumont, B.; Launay, M.; Seidel, S. J.
10.1101/2023.10.26.564162 — plant biology — Posted on 2023-12-17
1835 Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.
Chen, J.; Landback, P.; Arsala, D.; Guzzetta, A.; Xia, S.; Atlas, J.; Dong, C.; Sosa, D.; Zhang, Y.; Cheng, J.; Shen, B.; Long, M.
10.1101/2023.11.14.567139 — evolutionary biology — Posted on 2023-12-17
1840 Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
Bruter, A. V.; Varlamova, E. A.; Stavskaya, N. I.; Antysheva, Z. G.; Manskikh, V. N.; Tvorogova, A. V.; Korshunova, D. S.; Khamidullina, A. I.; Utkina, M. V.; Bogdanov, V. P.; Nikiforova, A. I.; Albert, E. A.; Maksimov, D. O.; Li, J.; Chen, M.; Shtil, A. A.; Roninson, I. B.; Mogila, V. A.; Silaeva, Y. Y.; Tatarskiy, V. V.
10.1101/2023.11.04.564913 — developmental biology — Posted on 2023-12-17
1841 Hypoxia drives HIF2-dependent macrophage cell cycle entry and susceptibility to lentiviral transduction
Meng, B.; Zhao, N.; Mlcochova, P.; Ferreira, I.; Ortmann, B.; Davis, T.; Rehwinkle, J.; Cook, S.; Maxwell, P.; Nathan, J.; Gupta, R. K.
10.1101/2023.12.15.571908 — cell biology — Posted on 2023-12-17
1842 H7 influenza A viruses bind sialyl-LewisX, a potential intermediate receptor between species
Spruit, C.; Palme, D. I.; Li, T.; Rios Carrasco, M.; Gabarroca Garcia, A.; Sweet, I.; Kuryshko, M.; Maliepaard, J. C. L.; Reiding, K. R.; Scheibner, D.; Boons, G.-J.; Abdelwhab, E. M.; de Vries, R. P.
10.1101/2023.12.15.571923 — molecular biology — Posted on 2023-12-17
1843 Exploring the genome and protein space of viruses
Lu, C.; Wu, Y.; Zhang, Z.; Mao, L.; Ge, X.; Wu, A.; Sun, F.; Jiang, Y.; Peng, Y.
10.1101/2022.11.05.515293 — microbiology — Posted on 2023-12-17
1845 A multi-channel TMS system enabling accurate stimulus orientation control during concurrent ultra-high-field MRI for preclinical applications
Souza, V. H.; Sinisalo, H.; Korhonen, J. T.; Paasonen, J.; Nyrhinen, M.; Nieminen, J. O.; Koponen, M. A.; Kettunen, M.; Gröhn, O.; Ilmoniemi, R. J.
10.1101/2023.08.10.552401 — neuroscience — Posted on 2023-12-17
1846 Restoring AIBP expression in the retina provides neuroprotection in glaucoma
Ju, W.-K.; Ha, Y.; Choi, S.; Kim, K.-Y.; Bastola, T.; Kim, J.; Weinreb, R. N.; Zhang, W.; Miller, Y. I.; Choi, S.-H.
10.1101/2023.10.16.562633 — neuroscience — Posted on 2023-12-17
1849 Dorsal Motor Vagal Neurons Can Elicit Bradycardia and Reduce Anxiety-Like Behavior
Strain, M. M.; Conley, N. J.; Kauffman, L. S.; Espinoza, L.; Fedorchak, S.; Martinez, P. C.; Crook, M. E.; Jalil, M.; Hodes, G. E.; Abbott, S. B. G.; Guler, A. D.; Campbell, J. N.; Boychuk, C. R.
10.1101/2023.11.14.566855 — neuroscience — Posted on 2023-12-17
1850 The AMsh glia of C. elegans modulates the duration of touch-induced escape responses
Awe, T.; Aalimah, A.; Niha, S.; Kelly, L.; Adams, J.; Stein, W.; Vidal-Gadea, A. G.
10.1101/2023.12.13.571291 — neuroscience — Posted on 2023-12-17
1851 BrainAGE: Revisited and reframed machine learning workflow
Kalc, P.; Dahnke, R.; Hoffstaedter, F.; Gaser, C.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2022.11.21.517386 — neuroscience — Posted on 2023-12-17
1852 Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia
Zhou, L.; Ni, C.; Liao, R.; Tang, X.; Yi, T.; Ran, M.; Huang, M.; Liao, R.; Zhou, X.; Qin, D.; Wang, L.; Huang, F.; Xie, X.; Wan, Y.; Luo, J.; Wang, Y.; Wu, J.
10.1101/2023.12.16.571981 — pharmacology and toxicology — Posted on 2023-12-17
1853 Conformational Space Profile Enhances Generic Molecular Representation Learning
Wang, L.; Wang, S.; Yang, H.; Li, S.; Wang, X.; Zhou, Y.; Tian, S.; Liu, L.; Bai, F.
10.1101/2023.12.14.571629 — bioinformatics — Posted on 2023-12-17
1856 An ancient transcription activator is required for the multiciliogenesis program
Jiang, H.; Hua, M.; Ding, M.; Hu, J.; Zheng, S.; Wang, H.; Wang, W.; xu, c.; Xing, J.; Liu, H.; Zhao, X.; Hu, Z.
10.1101/2023.12.16.571971 — cell biology — Posted on 2023-12-16
1858 Complete genome of the Medicago anthracnose fungus, Colletotrichum destructivum, reveals a mini-chromosome-like region within a core chromosome.
LAPALU, N.; SIMON, A.; Lu, A.; Plaumann, P.-L.; Amselem, J.; Pigne, S.; Auger, A.; Koch, C.; Dallery, J.-F.; O'Connell, R. J.
10.1101/2023.12.16.571984 — genomics — Posted on 2023-12-16
1860 In vivo optimized three-photon imaging of intact mouse tibia links plasma cell motility to functional states in the bone marrow.
Niesner, R. A.; Rakhymzhan, A.; Fiedler, A. F.; Guenther, R.; Domingue, S.; Wooldridge, L.; Leben, R.; Cao, Y.; Bias, A.; Roodselaar, J.; Koehler, R.; Ulbricht, C.; Heidelin, J.; Andresen, V.; Beckers, I.; Haibel, A.; Duda, G.; Hauser, A. E.
10.1101/2023.12.16.571998 — biophysics — Posted on 2023-12-16
1869 Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis
Vannan, A.; Lyu, R.; Williams, A. L.; Negretti, N. M.; Mee, E. D.; Hirsh, J.; Hirsh, S.; Nichols, D. S.; Calvi, C. L.; Talor, C. J.; Polosukhin, V. V.; Serezani, A. P.; McCall, A. S.; Gokey, J. J.; Shim, H.; Ware, L. B.; Bacchetta, M. J.; Shaver, C. M.; Blackwell, T. S.; Kropski, J. A.; Walia, R.; Sucre, J. M.; McCarthy, D. J.; Banovich, N. E.
10.1101/2023.12.15.571954 — genomics — Posted on 2023-12-16
1874 Rescue of Impaired Blood-Brain Barrier in Tuberous Sclerosis Complex Patient Derived Neurovascular Unit
Brown, J.; Faley, S.; Judge, M.; Ward, P.; Ihrie, R. A.; Carson, R.; Armstrong, L.; Sahin, M.; Wikswo, J.; Ess, K.; Neely, D.
10.1101/2023.12.15.571738 — neuroscience — Posted on 2023-12-16
1876 Epigenetic disruption of the RARγ complex impairs its function to bookmark AR enhancer interactions required for enzalutamide sensitivity in prostate cancer
Wani, S. A.; Hussain, S.; Gray, J. S.; Nayak, D.; Tang, H.; Perez, L. M.; Long, M. D.; Siddappa, M.; McCabe, C.; Campbell, L.; Freeman, M. R.; Campbell, M. J.
10.1101/2023.12.15.571947 — cancer biology — Posted on 2023-12-16
1877 Osteopontin in colitis-associated carcinoma
Manna, S.; Sehn, M.; Cardoso da Silva, D.; Wiese, J. J.; Heldt, C.; Plumbom, I.; Conrad, T.; Husemann, C. C.; Kleo, K.; Derezanin, L.; Dony, V.; Farahani, S. K.; Weiss, F.; Kuehl, A. A.; Schallenberg, S.; Weiner, J.; Elezkurtaj, S.; Weixler, B.; Groene, J.; Siegmund, B.; Hummel, M.; Schumann, M.
10.1101/2023.12.15.571952 — cancer biology — Posted on 2023-12-16
1881 A cognitive map for value-guided choice in ventromedial prefrontal cortex
Veselic, S.; Muller, T.; Gutierrez, E.; Behrens, T.; Hunt, L. T.; Butler, J.; Kennerley, S.
10.1101/2023.12.15.571895 — neuroscience — Posted on 2023-12-16
1883 Evolution of Opsin Genes in Caddisflies (Insecta: Trichoptera)
Powell, A.; Heckenhauer, J.; Pauls, S. U.; Rios-Touma, B.; Kuranishi, R. B.; Holzenthal, R. W.; Razuri-Gonzales, E.; Bybee, S.; Frandsen, P. B.
10.1101/2023.12.15.571940 — genomics — Posted on 2023-12-16
1884 Hybrid adaptation is hampered by Haldane's sieve
Bautista, C.; Gagnon-Arsenault, I.; Utrobina, M.; Fijarczyk, A.; Bendixsen, D. P.; Stelkens, R.; Landry, C.
10.1101/2023.12.15.571924 — evolutionary biology — Posted on 2023-12-16
1886 High-energy demand and nutrient exhaustion in MTCH2 knockout cells
Chourasia, S.; Petucci, C.; Wang, H.; Han, X.; Sivan, E.; Brandis, A.; Mehlman, T.; Malitsky, S.; Itkin, M.; Rotkopf, R.; Regev, L.; Zaltsman, Y.; Gross, A.
10.1101/2023.12.15.571941 — cell biology — Posted on 2023-12-16
1890 Imaging the voltage of neurons distributed across entire brains of larval zebrafish
Wang, Z.; Zhang, J.; Symvoulidis, P.; Guo, W.; Zhang, L.; Wilson, M. A.; Boyden, E. S.
10.1101/2023.12.15.571964 — neuroscience — Posted on 2023-12-16
1891 Building synthetic biosensors using red blood cell proteins
Dolberg, T. B.; Gunnels, T. F.; Ling, T.; Sarnese, K. A.; Crispino, J. D.; Leonard, J. N.
10.1101/2023.12.16.571988 — synthetic biology — Posted on 2023-12-16
1894 Hypoxia drives HIF2-dependent macrophage cell cycle entry and susceptibility to lentivira transduction
Meng, B.; Zhao, N.; Mlcochova, P.; Ferreira, I.; Ortmann, B.; Davis, T.; Rehwinkle, J.; Cook, S.; Maxwell, P.; Nathan, J.; Gupta, R. K.
10.1101/2023.12.15.571908 — cell biology — Posted on 2023-12-16
1895 An RXLR effector targets ER-Golgi interface to induce ER stress and necrotic cell death
Kim, J.; Kaleku, J.; Kim, H.; Kang, M.; Kang, H. J.; segonzac, c.; Woo, J.; Park, E.; Choi, D.
10.1101/2023.12.15.571945 — plant biology — Posted on 2023-12-16
1898 Synergistic insulation of regulatory domains by developmental genes and clusters of CTCF sites
Ealo, T.; Sanchez-Gaya, V.; Respuela, P.; Munoz-San Martin, M.; Martin-Batista, E.; Haro, E.; Rada-Iglesias, A.
10.1101/2023.12.15.571760 — genetics — Posted on 2023-12-16
1901 Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
Henderson, R.; Anasti, K.; Manne, K.; Stalls, V.; Saunders, C.; Bililign, Y.; Williams, A.; Bubphamala, J.; Montani, M.; Kachhap, S.; Li, J.; Jaing, C.; Newman, A.; Cain, D.; Lu, X.; Venkatayogi, S.; Berry, M.; Wagh, K.; Korber, B.; Saunders, K. O.; Tian, M.; Alt, F.; Wiehe, K.; Acharya, P.; Alam, S. M.; Haynes, B. F.
10.1101/2023.12.15.571700 — immunology — Posted on 2023-12-16
1902 Locus Coeruleus Norepinephrine Neurons Facilitate Orbitofrontal Cortex Remapping and Behavioral Flexibility
Ogg, M. C.; Franks, H. T.; Lansdell, B. J.; Hughes, A. C.; Lee, J.; Nolen, H. G.; Shirinifard, A.; Lindsay, S.
10.1101/2023.12.15.571858 — neuroscience — Posted on 2023-12-16
1903 Data driven discovery and quantification of hyperspectral leaf reflectance phenotypes across a maize diversity panel
Tross, M. C.; Grzybowski, M. W.; Jubery, T. Z.; Grove, R. J.; Nishimwe, A. V.; Torres-Rodriguez, J. V.; Sun, G.; Ganapathysubramanian, B.; Schnable, J. C.
10.1101/2023.12.15.571950 — plant biology — Posted on 2023-12-16
1905 Uncovering kinesin dynamics in neurites with MINFLUX
Wirth, J. O.; Schentarra, E. M.; Scheiderer, L.; Palacios, V. M.; Tarnawski, M.; Hell, S. W.
10.1101/2023.12.15.571866 — biophysics — Posted on 2023-12-16
1908 Characterizing the viscoelastic properties of different fibroblasts in 2D and 3D collagen gels
Perez-Dominguez, S.; Sanz-Fraile, H.; Martinez Vidal, L.; Alfano, M.; Otero, J.; Radmacher, M.
10.1101/2023.12.15.571880 — biophysics — Posted on 2023-12-16
1912 Downscaling global reference points to assess the sustainability of local fisheries
Zamborain-Mason, J.; Connolly, S. R.; Macneil, M. A.; Barnes, M. L.; Bauman, A. G.; Feary, D. A.; Huertas, V.; Januchowski-Hartley, F. A.; Lau, J. D.; Mihalistis, M.; Cinner, J. E.
10.1101/2023.12.15.571896 — ecology — Posted on 2023-12-16
1915 Dia2 formin controls receptor activity by organizing plasma membrane lipid partitioning at the nanoscale
Li, C.; Hamon, Y.; Mazaud, D.; Dessard, M.; Gonzalez Troncoso, P.; He, H.-t.; Lamaze, C.; Blouin, C. M.
10.1101/2023.12.15.571857 — cell biology — Posted on 2023-12-16
1916 Frequency-dependent phase entrainment of cortical cell types during tACS: Converging modeling evidence
Gaugain, G.; Al Harrach, M.; Yochum, M.; Wendling, F.; Bikson, M.; Modolo, J.; Nikolayev, D.
10.1101/2023.12.15.571874 — neuroscience — Posted on 2023-12-16
1917 Aberrant Connectivity Across the Lifespan in a Mouse Model of Alzheimer's disease and Rescue by mGlur5 Modulator Treatment
Mandino, F.; Shen, X.; Desrosiers-Gregoire, G.; O'Connor, D.; Mukherjee, B.; Owens, A.; Qu, A.; Onofrey, J.; Papademetris, X.; Chakravarty, M.; Strittmatter, S. M.; Lake, E. M.
10.1101/2023.12.15.571715 — neuroscience — Posted on 2023-12-16
1918 Neuronal Avalanches in Naturalistic Speech and Music Listening
Neri, M.; Runfola, C.; te Rietmolen, N. A. G.; Sorrentino, P.; Schon, D.; Morillon, B.; Rabuffo, G.
10.1101/2023.12.15.571888 — neuroscience — Posted on 2023-12-16
1922 The dimorphic diaspore model Aethionema arabicum (Brassicaceae): Distinct molecular and morphological control of responses to parental and germination temperatures
Chandler, J. O.; Wilhelmsson, P. K. I.; Fernandez-Pozo, N.; Graeber, K.; Arshad, W.; Perez, M.; Steinbrecher, T.; Ullrich, K. K.; Nguyen, T.-P.; Merai, Z.; Mummenhoff, K.; Theissen, G.; Strnad, M.; Mittelsten Scheid, O.; Schranz, M. E.; Petrik, I.; Tarkowska, D.; Novak, O.; Rensing, S. A.; Leubner-Metzger, G.
10.1101/2023.12.14.571707 — plant biology — Posted on 2023-12-16
1923 Membrane lipid poly-unsaturation selectively affects ligand induced dopamine D2 receptor internalization
Perrais, D.; Baccouch, R.; Sposini, S.; De Smedt-Peyrusse, V.; Heuninck, J.; Durroux, T.; Trifilieff, P.; Alves, I.
10.1101/2023.12.14.571632 — cell biology — Posted on 2023-12-16
1924 Molecular epidemiology of Candida africana isolates collected from vagina swabs in French Guiana.
Bigot, J.; Kalboussi, Y.; Bonkoto Nkoy, Y.; Benmostefa, A.; Vellaissamy, S.; Benzerara, Y.; Saint-Rose, V.; Blanchet, D.; Demar, M.; Guitard, J.; Hennequin, C.
10.1101/2023.12.13.571500 — microbiology — Posted on 2023-12-16
1928 Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Colinet, D.; Cavigliasso, F.; Leobold, M.; Pichon, A.; Urbach, S.; Cazes, D.; Poullet, M.; Belghazi, M.; Volkoff, A.-N.; Drezen, J.-M.; Gatti, J.-L.; Poirie, M.
10.1101/2023.06.05.543686 — evolutionary biology — Posted on 2023-12-16
1929 SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma
Daley, B. R.; Sealover, N. E.; Sheffels, E.; Hughes, J. M.; Gerlach, D.; Hofmann, M. H.; Kostyrko, K.; Mair, B.; Linke, A.; Beckley, Z.; Frank, A.; Dalgard, C. L.; Kortum, R. L.
10.1101/2023.12.07.570642 — cancer biology — Posted on 2023-12-15
1930 Targetable leukemia dependency on noncanonical PI3Kγ signaling
Luo, Q.; Raulston, E. G.; Prado, M. A.; Wu, X.; Gritsman, K.; Booth, C. A. G.; Xu, R.; van Galen, P.; Doench, J. G.; Shimony, S.; Long, H. W.; Neuberg, D. S.; Paulo, J. A.; Lane, A. A.
10.1101/2023.12.15.571909 — cancer biology — Posted on 2023-12-15
1931 Catalytically inactive dKbCas12d guided by sgRNA and new insights into its binding through a single-molecule approach
Alekseev, A.; Klimko, V.; Frantsuzova, I.; Abramova, M.; Vinnik, V.; Vasileva, A.; Selkova, P.; Khodorkovskii, M.; Arseniev, A.
10.1101/2023.12.12.571249 — biophysics — Posted on 2023-12-15
1932 Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states
Lin, D. Y.-w.; Kueffer, L. E.; Juneja, P.; Wales, T. E.; Engen, J. R.; Andreotti, A. H.
10.1101/2023.06.02.543453 — biophysics — Posted on 2023-12-15
1933 Personalized Pangenome References
Siren, J.; Eskandar, P.; Ungaro, M. T.; Hickey, G.; Eizenga, J. M.; Novak, A. M.; Chang, X.; Chang, P.-C.; Kolmogorov, M.; Carroll, A.; Monlong, J.; Paten, B.
10.1101/2023.12.13.571553 — bioinformatics — Posted on 2023-12-15
1934 SOAR elucidates disease mechanisms and empowers drug discovery through spatial transcriptomics
Li, Y.; Dennis, S.; Hutch, M.; Ding, Y.; Zhou, Y.; Li, Y.; Pillai, M.; Ghotbaldini, S.; Garcia, M. A.; Broad, M.; Mao, C.; Cheng, F.; Zeng, Z.; Luo, Y.
10.1101/2022.04.17.488596 — bioinformatics — Posted on 2023-12-15
1935 Adaptive capacity of a DNA polymerase clamp-loader ATPase complex
Subramanian, S.; Zhang, W.; Nimkar, S.; Kamel, M.; O'Donnell, M. E.; Kuriyan, J.
10.1101/2023.10.18.562948 — biochemistry — Posted on 2023-12-16
1942 Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast
Chalivendra, S.; Shi, S.; Li, x.; Kuang, Z.; Giovinazzo, J.; Zhang, L.; Rossi, J.; Saviola, A.; Wang, J.; Welty, R.; Liu, S.; Vaeth, K.; Zhou, H.; Hansen, K.; Taliaferro, M.; zhao, R.
10.1101/2023.12.15.571893 — biochemistry — Posted on 2023-12-15
1943 The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA
Hardikar, S.; Ren, R.; Ying, Z.; Horton, J. R.; Bramble, M. D.; Liu, B.; Lu, Y.; Liu, B.; Dan, J.; Zhang, X.; Cheng, X.; Chen, T.
10.1101/2023.12.15.571946 — molecular biology — Posted on 2023-12-15
1945 Diet-driven differential response of Akkermansia muciniphila modulates pathogen susceptibility
Wolter, M.; Grant, E.; Boudaud, M.; Pudlo, N.; Vasconcelos Pereira, G.; Eaton, K.; Martens, E.; Desai, M. S.
10.1101/2023.12.15.571894 — microbiology — Posted on 2023-12-15
1947 A long-acting prolactin to combat lactation insufficiency
Kready, K.; Doiron, K.; Redfield Chan, K.; Way, J. C.; Justman, Q.; Powe, C. E.; Silver, P. A.
10.1101/2023.12.15.571886 — synthetic biology — Posted on 2023-12-15
1948 Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
Rodriguez Palomo, I.; Nair, B. A. B.; Chiang, Y.; Dekker, J.; Dartigues, B.; Mackie, M.; Evans, M.; Macleod, R.; Olsen, J.; Collins, M. J.
10.1101/2023.12.15.571577 — bioinformatics — Posted on 2023-12-15
1949 Structural and mechanistic views of enzymatic, heme-dependent nitrogen-nitrogen bond formation
Higgins, M. A.; Shi, X.; Soler, J.; Harland, J. B.; Parkkila, T.; Lehnert, N.; Garcia-Borras, M.; Du, Y.-L.; Ryan, K. S.
10.1101/2023.12.15.571702 — biochemistry — Posted on 2023-12-15
1952 DNA methylation-environment interactions in the human genome
Johnston, R. A.; Aracena, K. A.; Barreiro, L. B.; Lea, A. J.; Tung, J.
10.1101/2023.05.19.541437 — genomics — Posted on 2023-12-15
1961 AAV-mediated gene therapy in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia
Leung, K.-Y.; Santos, C.; De Castro, S. C.; Gold-Diaz, D.; Copp, A.; Waddington, S.; Greene, N.
10.1101/2023.12.15.571844 — molecular biology — Posted on 2023-12-15
1962 The histone methyltransferase SETD2 regulates HIV expression and latency through a post-transcriptional mechanism.
Bussey-Sutton, C. R.; Ward, A.; Turner, A.-M. W.; Peterson, J. J.; Emery, A.; Longoria, A.; Margolis, D. M.; Strahl, B.; Browne, E. P.
10.1101/2023.12.15.571871 — microbiology — Posted on 2023-12-15
1966 Synergistic Effects of Sulopenem in Combination with Cefuroxime or Durlobactam against Mycobacterium abscessus
Dousa, K. M.; Shin, E.; Kurz, S. G.; Plummer, M.; Nantongo, M.; Bethel, C. R.; Taracila, M. A.; Nguyen, D. C.; Kreiswith, B. N.; Daley, C. L.; Remy, K. E.; Holland, S.; Bonomo, R. A.
10.1101/2023.12.15.571879 — microbiology — Posted on 2023-12-15
1969 Dynamics and quantitative contribution of the aminoglycoside 6'-N-acetyltransferase type Ib to amikacin resistance
d'Udekem d'Acoz, O.; Hue, F.; Ye, T.; Wang, L.; Leroux, M.; Rajngewerc, L.; Tran, T.; Phan, K.; Ramirez, M. S.; Reisner, W.; Tolmasky, M.; Reyes Lamothe, R.
10.1101/2023.09.05.556435 — microbiology — Posted on 2023-12-15
1970 TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo
Kime, J.; Bose, D.; Arainga, M.; Haque, M. R.; Fennessey, C. M.; Caddell, R. A.; Thomas, Y.; Ferrell, D. E.; Ali, S.; Grody, E.; Goyal, Y.; Cicala, C.; Arthos, J.; Keele, B. F.; Vaccari, M.; Lorenzo-Redondo, R.; Hope, T. J.; Villinger, F. J.; Marinelli, E.
10.1101/2023.09.05.556422 — immunology — Posted on 2023-12-15
1972 Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission
Cuhadar, U.; Calzado-Reyes, L.; Pascual-Caro, C.; Aberra, A. S.; Ritzau-Jost, A.; Aggarwal, A.; Ibata, K.; Podgorski, K.; Yuzaki, M.; Geis, C.; Hallermann, S.; Hoppa, M. B.; de Juan-Sanz, J.
10.1101/2022.07.03.498586 — neuroscience — Posted on 2023-12-15
1973 Methods for decoding cortical gradients of functional connectivity
Peraza, J. A.; Salo, T.; Riedel, M. C.; Bottenhorn, K. L.; Poline, J.-B.; Dockes, J.; Kent, J. D.; Bartley, J. E.; Flannery, J. S.; Hill-Bowen, L. D.; Lobo, R. P.; Poudel, R.; Ray, K. L.; Robinson, J. L.; Laird, R. W.; Sutherland, M. T.; de la Vega, A.; Laird, A. R.
10.1101/2023.08.01.551505 — neuroscience — Posted on 2023-12-15
1975 DNA binding and bridging by human CtIP in the healthy and diseased states
Lokanathan Balaji, S.; De Braganca, S.; Balaguer-Perez, F.; Northall, S.; Wilkinson, O. J.; Aicart-Ramos, C.; Sobott, F.; Seetaloo, N.; Moreno-Herrero, F.; Dillingham, M. S.
10.1101/2023.12.14.571649 — biochemistry — Posted on 2023-12-15
1977 AlphaFold2 enables accurate deorphanization of ligands to single-pass receptors
Banhos Danneskiold-Samsoee, N.; Kavi, D.; Jude, K. M.; Nissen, S. B.; Wat, L. W.; Coassolo, L.; Zhao, M.; Asae Santana-Oikawa, G.; Broido, B. B.; Garcia, K. C.; Svensson, K. J.
10.1101/2023.03.16.531341 — biochemistry — Posted on 2023-12-15
1979 The bacterial community of the European spruce bark beetle in space and time
Moussa, A.; Nones, S.; Vannucchi, P. E.; Shahzad, G.-R.; Dittmer, J.; Corretto, E.; Schebeck, M.; Faccoli, M.; Battisti, A.; Stauffer, C.; Schuler, H.
10.1101/2023.04.28.538755 — ecology — Posted on 2023-12-15
1983 RNA-guided RNA silencing by an Asgard archaeal Argonaute
Bastiaanssen, C.; Ugarte, P. B.; Kim, K.; Feng, Y.; Finocchio, G.; Anzelon, T. A.; Kostlbacher, S.; Tamarit, D.; Ettema, T. J. G.; Jinek, M.; MacRae, I. J.; Joo, C.; Swarts, D. C.; Wu, F.
10.1101/2023.12.14.571608 — microbiology — Posted on 2023-12-15
1984 In vitro antimicrobial mechanism of diacerein and potential to reverse MRSE resistance to β-lactams
Fu, C.; Xu, Y.; Mao, L.; Zheng, C.; Shen, Y.; Ling, X.; Zhou, Y.; Yin, Y.; Lou, Y.; Zheng, M.
10.1101/2023.12.15.571937 — microbiology — Posted on 2023-12-15
1985 The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner
Wallings, R.; McFarland, K.; Staley, H.; Neighbarger, N.; Schaake, S.; Brueggemann, N.; Zittel, S.; Usnich, T.; Klein, C.; Sammler, E.; Tansey, M. G.
10.1101/2023.10.12.562063 — immunology — Posted on 2023-12-15
1986 High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster
Darby, A. M.; Okoro, D. O.; Aredas, S. N.; Frank, A. M.; Pearson, W. H.; Dionne, M. S.; Lazzaro, B. P.
10.1101/2023.12.07.570705 — immunology — Posted on 2023-12-15
1991 Insights from a survey of mentorship experiences by graduate and postdoctoral researchers
Sarabipour, S.; Niemi, N. M.; Burgess, S. J.; Smith, C. T.; Bisson Filho, A. W.; Ibrahim, A.; Clark, K.
10.1101/2023.05.05.539640 — scientific communication and education — Posted on 2023-12-15
1992 Determinants of cerebral blood flow and arterial transit time in healthy older adults
Feron, J.; Segaert, K.; Rahman, F.; Fosstveit, S.; Joyce, K. E.; Gilani, A.; Lohne-Seiler, H.; Bernsten, S.; Mullinger, K. J.; Lucas, S. J. E.
10.1101/2023.12.13.571578 — physiology — Posted on 2023-12-15
1993 VoltRon: A Spatial Omics Analysis Platform for Multi-Resolution and Multi-omics Integration using Image Registration
Manukyan, A.; Bahry, E.; Wyler, E.; Becher, E.; Pascual-Reguant, A.; Plumbom, I.; Dikmen, H. O.; Elezkurtaj, S.; Conrad, T.; Altmüller, J.; Hauser, A. E.; Hocke, A.; Radbruch, H.; Schmidt, D.; Landthaler, M.; Akalin, A.
10.1101/2023.12.15.571667 — bioinformatics — Posted on 2023-12-15
1994 Na+/H+ antiporter activity by respiratory complex I controls mitochondrial Δ{psi} and is impaired in LHON disease
Hernansanz-Agustin, P.; Morales-Vidal, C.; Calvo, E.; Natale, P.; Marti-Mateos, Y.; Jaroszewicz, S.; Cabrera-Alarcon, J. L.; Lopez-Montero, I.; Vazquez, J.; Enriquez, J. A.
10.1101/2023.05.30.542932 — biochemistry — Posted on 2023-12-15
1997 pyQCM-BraTaDio: A tool for visualization, data mining, and modeling of Quartz crystal microbalance with dissipation data
Pardi, B. M.; Ahmed, S. T.; Jonguitud Flores, S.; Flores, W.; Mears, L. L. M.; Yanez Soto, B.; Andresen Eguiluz, R. C.
10.1101/2023.12.15.571789 — bioengineering — Posted on 2023-12-15
1998 Experimental Validation of an Organ-on-Chip for Mechanical Stimulation of Cell Cultures
Testa, M.; Tornabene, S.; Di Leonardo, S.; Burriesci, G.; La Carrubba, V.; Lopresti, F.
10.1101/2023.12.15.571835 — bioengineering — Posted on 2023-12-15
2000 Recent evolution of large offspring size and post-fertilization nutrient provisioning in swordtails
Payne, C. Y.; Ly, D.; Rodriguez-Soto, R. A.; Powell, D. L.; Robles, N. D.; Gunn, T. R.; Baczenas, J. J.; Bergman, A. J.; Pollock, A. C.; Moran, B. M.; Baker, J. C.; Reznick, D.; Schumer, M.
10.1101/2023.12.15.571831 — evolutionary biology — Posted on 2023-12-15
2004 The regulation of polar flagella assembly in Pseudomonas putida
Pulido-Sanchez, M.; Leal-Morales, A.; Lopez-Sanchez, A.; Cava, F.; Govantes, F.
10.1101/2023.12.15.571843 — microbiology — Posted on 2023-12-15
2006 Curvature-induced lipid sorting beyond the critical packing parameter
Konig, M.; de Vries, R.; Grunewald, F.; Marrink, S.-J.; Pezeshkian, W.
10.1101/2023.12.15.571845 — biophysics — Posted on 2023-12-15
2007 MeXpose - A modular imaging pipeline for the quantitative assessment of cellular metal bioaccumulation
Braun, G.; Schaier, M.; Werner, P.; Theiner, S.; Zanghellini, J.; Wisgrill, L.; Fyhrquist, N.; Koellensperger, G.
10.1101/2023.12.15.571675 — bioinformatics — Posted on 2023-12-15
2008 Bioactive coatings on 3D printed polycaprolactone scaffolds for bone regeneration: a novel murine femur defect model for examination of the biomaterial capacity for repair.
Marshall, K. M.; Wojciechowski, J. P.; Jayawarna, V.; Hasan, A.; Echalier, C.; Callens, S. J. P.; Yang, T.; Kanczler, J. M.; Dawson, J. I.; Mata, A.; Salmeron-Sanchez, M.; Stevens, M. M.; Oreffo, R. O. C.
10.1101/2023.12.15.569064 — bioengineering — Posted on 2023-12-15
2009 Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation
Varshney, A.; Manickam, N.; Orchard, P.; Tovar, A.; Zhang, Z.; Feng, F.; Erdos, M. R.; Narisu, N.; Ventresca, C.; Nishino, K.; Rai, V.; Stringham, H.; Jackson, A. U.; Tamsen, T.; Gao, C.; Yang, M.; Koues, O. I.; Welch, J. D.; Burant, C. F.; Williams, L. K.; Jenkinson, C.; DeFronzo, R. A.; Norton, L.; Saramies, J.; Lakka, T. A.; Laakso, M.; Tuomilehto, J.; Mohlke, K. L.; Kitzman, J. O.; Koistinen, H. A.; Liu, J.; Boehnke, M.; Collins, F. S.; Scott, L. J.; Parker, S. C.
10.1101/2023.12.15.571696 — genomics — Posted on 2023-12-15
2011 A Fungal Spore Calendar for England: Analysis of 13 years of Daily Concentrations at Leicester, UK
Symon, F. A.; Anees-Hill, S.; Satchwell, J.; Fairs, A.; Edwards, R.; Wardlaw, A.; Cuthbertson, L.; Pashley, C. H.; Hansell, A.
10.1101/2023.12.15.571848 — ecology — Posted on 2023-12-15
2012 A model for maxilloturbinate morphogenesis in seals
Kings, J. E.; Folkow, L. P.; Hammer, O.; Kjelstrup, S.; Mason, M. J.; Xiong, F.; Flekkoy, E. G.
10.1101/2023.12.15.571824 — developmental biology — Posted on 2023-12-15
2014 Parallel Molecular Data Storage by Printing Epigenetic Bits on DNA
Zhang, C.; Wu, R.; Sun, F.; Lin, Y.; Zhang, Y.; Liang, Y.; Chen, Y.; Teng, J.; Song, Z.; Liu, N.; Ouyang, Q.; Qian, L.; Yan, H.
10.1101/2023.12.15.571646 — biochemistry — Posted on 2023-12-15
2017 Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation
Olmedillas, E.; Rajamanickam, R. R.; Diaz, R.; Sosa Batiz, F. A.; Zandonatti, M. A.; Harkins, S. S.; Shresta, S.; Hastie, K.; Saphire, E. O.
10.1101/2023.12.14.571764 — microbiology — Posted on 2023-12-15
2018 SARS-CoV-2 and other coronaviruses in rats, Berlin, Germany, 2023
Wernike, K.; Mehl, C.; Aebischer, A.; Heising, M.; Ulrich, R. G.; Beer, M.
10.1101/2023.12.15.571826 — microbiology — Posted on 2023-12-15
2020 Changes in intra- and interlimb reflexes from hindlimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats
Mari, S.; Lecomte, C. G.; Merlet, A. N.; Audet, J.; Yassine, S.; Eddaoui, O.; Genois, G.; Nadeau, C.; Harnie, J.; Rybak, I. A.; Prilutsky, B. I.; Frigon, A.
10.1101/2023.12.15.571869 — neuroscience — Posted on 2023-12-15
2022 Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist
Um, P. K.; Praharaj, M.; Lombardo, K. A.; Yoshida, T.; Matoso, A.; Baras, A. S.; Zhao, L.; Srikrishna, G.; Huang, J.; Prasad, P.; Kates, M.; McConkey, D.; Pardoll, D. M.; Bishai, W. R.; Bivalacqua, T. J.
10.1101/2023.12.15.571740 — cancer biology — Posted on 2023-12-15
2024 A versatile and upgraded version of the LundTax classification algorithm applied to independent cohorts
Aramendia Cotillas, E.; Bernardo, C.; Veerla, S.; Liedberg, F.; Sjodahl, G.; Eriksson, P.
10.1101/2023.12.15.571519 — bioinformatics — Posted on 2023-12-15
2026 MFSD1 in complex with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Jungnickel, K. E. J.; Guelle, O.; Iguchi, M.; Dong, W.; Kotov, V.; Gabriel, F.; Debacker, C.; Dairou, J.; McCort-Tranchepain, I.; Laqtom, N. N.; Chan, S. H.; Ejima, A.; Sato, K.; Massa Lopez, D.; Saftig, P.; Mehdipour, A. R.; Abu-Remaileh, M.; Gasnier, B.; Low, C.; Damme, M.
10.1101/2023.12.15.570541 — biochemistry — Posted on 2023-12-15
2028 Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents
Li, Z.; Mukherjee, D.; Duric, B.; Austin-Zimmerman, I.; Trotta, G.; Spinazzola, E.; Quattrone, D.; Murray, R. M.; Di Forti, M.
10.1101/2023.12.15.571463 — animal behavior and cognition — Posted on 2023-12-15
2029 Time-resolved and multifactorial profiling in single cells resolves the order of heterochromatin formation events during X-chromosome inactivation
Kefalopoulou, S.; Rullens, P. M. J.; de Luca, K. L.; de Vries, S. S.; Korthout, T.; van Oudenaarden, A.; Zeller, P.; Kind, J.
10.1101/2023.12.15.571749 — genomics — Posted on 2023-12-15
2030 Claudin-4 polymerizes after the incorporation of just two extracellular claudin-3 residues
van der Veen, R. E.; Piontek, J.; Bieck, M.; Saiti, A.; Gonschior, H.; Lehmann, M.
10.1101/2023.12.15.571691 — cell biology — Posted on 2023-12-15
2031 Development And Characterization Of A Non-Human Primate Model Of Disseminated Synucleinopathy
Rico, A. J.; Corcho, A.; Chocarro, J.; Ariznabarreta, G.; Roda, E.; Honrubia, A.; Arnaiz Esteban, P.; Lanciego, J. L.
10.1101/2023.12.15.571818 — neuroscience — Posted on 2023-12-15
2032 A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease
Aldous, S. G.; Smith, E. J.; Landles, C.; Osborne, G. F.; Canibano-Pico, M.; Nita, I. M.; Phillips, J.; Zhang, Y.; Jin, B.; Hirst, M. B.; Benn, C. L.; Bond, B. C.; Edelmann, W.; Greene, J. R.; Bates, G. P.
10.1101/2023.12.15.571088 — neuroscience — Posted on 2023-12-15
2033 AAV-mediated interneuron-specific gene replacement for Dravet syndrome
Mich, J. K.; Ryu, J.; Wei, A. D.; Gore, B. B.; Guo, R.; Bard, A. M.; Martinez, R. A.; Bishaw, Y.; Luber, E.; Oliveira Santos, L. M.; Miranda, N.; Ramirez, J.-M.; Ting, J. T.; Lein, E. S.; Levi, B. P.; Kalume, F. K.
10.1101/2023.12.15.571820 — neuroscience — Posted on 2023-12-15
2036 Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
Rodriguez Palomo, I.; Nair, B. A. B.; Chiang, Y.; Dekker, J.; Dartigues, B.; Mackie, M.; Evans, M.; Macleod, R.; Olsen, J.; Collins, M. J.
10.1101/2023.12.15.571577 — bioinformatics — Posted on 2023-12-15
2037 An Integrated Optogenetic and Bioelectronic Platform for Regulating Cardiomyocyte Function
Bolonduro, O. A.; Chen, Z.; Lai, Y.-R.; Cote, M.; Rao, A. A.; Liu, H.; Tzanakakis, E. S.; Timko, B. P.
10.1101/2023.12.15.571704 — bioengineering — Posted on 2023-12-15
2038 Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the Integrated Stress Response
Yan, Y.; Shetty, M.; Harding, H. P.; George, G.; Zyryanova, A.; Labbe, K.; Mafi, A.; Hao, Q.; Sidrauski, C.; Ron, D.
10.1101/2023.12.15.571226 — biochemistry — Posted on 2023-12-15
2039 SRRM2 splicing factor modulates cell fate in early development
Carvalho, S.; Zea-Redondo, L.; Tang, T. C. C.; Stachel-Braum, P.; Miller, D. C.; Caldas, P.; Kukalev, A.; Diecke, S.; Grosswendt, S.; Grosso, A. R.; Pombo, A.
10.1101/2023.12.15.571825 — developmental biology — Posted on 2023-12-15
2043 Darkness inhibits autokinase activity of bacterial bathy phytochromes
Huber, C.; Strack, M.; Schultheiss, I.; Pielage, J.; Mechler, X.; Hornbogen, J.; Diller, R.; Frankenberg-Dinkel, N.
10.1101/2023.12.15.571814 — microbiology — Posted on 2023-12-15
2047 NMDAR Phosphoproteome Controls Synaptic Growth and Learning
Funahashi, Y.; Ahammad, R. U.; Zhang, X.; Hossen, E.; Kawatani, M.; Nakamuta, S.; Yoshimi, A.; Wu, M.; Wang, H.; Wu, M.; Li, X.; Faruk, M. O.; Shohag, M. H.; Lin, Y.-H.; Tsuboi, D.; Nishioka, T.; Kuroda, K.; Amano, M.; Noda, Y.; Yamada, K.; Sakimura, K.; Nagai, T.; Yamashita, T.; Uchino, S.; Kaibuchi, K.
10.1101/2023.12.15.571360 — neuroscience — Posted on 2023-12-15
2050 Modeling Glioma Oncostreams In Vitro: Spatiotemporal Dynamics of their Formation, Stability, and Disassembly
Faisal, S. M.; Clewner, J. E.; Stack, B.; Varela, M. L.; Comba, A.; Motsch, S.; Castro, M. G.; Lowenstein, P. R.
10.1101/2023.12.14.571722 — cancer biology — Posted on 2023-12-15
2051 CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC
Zhu, H.; Liu, Q.; Meng, Q.; Zhang, L.; Lan, J.; Zhu, D.; Chen, Y.; Aishan, N.; Ouyang, X.; Zhang, S.; Jin, L.; Xiao, L.; Wang, L.; Li, L.; Ji, F.
10.1101/2023.12.14.571783 — cancer biology — Posted on 2023-12-15
2055 Encompassing view of spatial and single-cell RNA-seq renews the role of the microvasculature in human atherosclerosis
Bleckwehl, T.; Maryam, S.; Babler, A.; Bosteen, M.; Nyberg, M.; Halder, M.; Hvid, H.; Pyke, C.; Voetmann, L. M.; Das, V.; Baumgart, S.; Kramann, R.; Hayat, S.
10.1101/2023.12.15.571796 — bioinformatics — Posted on 2023-12-15
2057 Covalent Attachment of Horseradish Peroxidase to Single-Walled Carbon Nanotubes for Hydrogen Peroxide Detection
Ledesma, F.; Nishitani, S.; Cunningham, F. J.; Hubbard, J. D.; Yim, D.; Lui, A.; Chio, L.; Murali, A.; Landry, M. P.
10.1101/2023.12.14.571773 — bioengineering — Posted on 2023-12-15
2059 Saturation genome editing-based functional evaluation and clinical classification of BRCA2 single nucleotide variants
Huang, H.; Hu, C.; Na, J.; Hart, S. N.; Gnanaolivu, R. D.; Abozaid, M.; Rao, T.; Tecleab, Y. A.; Pesaran, T.; Lyra, P. C. M.; Karam, R.; Yadav, S.; Domchek, S. M.; de la Hoya, M.; Robson, M.; Mehine, M.; Bandlamudi, C.; Mandelker, D.; Monteiro, A. N. A.; Boddicker, N.; Chen, W.; Richardson, M. E.; Couch, F. J.
10.1101/2023.12.14.571597 — genomics — Posted on 2023-12-15
2062 Levodopa reduces consumption of multiple classes of addictive substances in rats
Farero, R. D.; Holtz, N. A.; Lee, S. J.; Kruse, L. C.; Clark, J. J.; Phillips, P. E. M.
10.1101/2023.12.14.570833 — animal behavior and cognition — Posted on 2023-12-15
2064 Genetic landscape of an in vivo protein interactome
Besse, S.; Sakaguchi, T.; Gauthier, L.; Sahaf, Z.; Peloquin, O.; Gonzalez, L.; Castellanos-Girouard, X.; Kocatug, N.; Matta, C.; Hussin, J. G.; Michnick, S. W.; Serohijos, A. W. R.
10.1101/2023.12.14.571726 — genomics — Posted on 2023-12-15
2065 AVENGERS: Analysis of Variant Effects using Next Generation sequencing to Enhance BRCA2 Stratification
Sahu, S.; Galloux, M.; Southon, E.; Caylor, D.; Sullivan, T.; Arnaudi, M.; Geh, J.; Chari, R.; Papaleo, E.; Sharan, S. K.
10.1101/2023.12.14.571713 — genetics — Posted on 2023-12-15
2066 Dysregulation of innate immune signaling in animal models of Spinal Muscular Atrophy
Garcia, E. L.; Steiner, R. E.; Raimer, A. C.; Herring, L. E.; Matera, A. G.; Spring, A. M.
10.1101/2023.12.14.571739 — genetics — Posted on 2023-12-15
2068 Extreme in Every Way: Exceedingly Low Genetic Diversity in Snow Leopards Due to Persistently Small Population Size
Solari, K. A.; Morgan, S. A.; Poyarkov, A. D.; Weckworth, B.; Samelius, G.; Sharma, K.; Ostrowski, S.; Ramakrishnan, U.; Kubanychbekov, Z.; Kachel, S.; Johansson, O.; Lkhagvajav, P.; Hemmingmoore, H.; Aleksandrov, D.; Bayaraa, M.; Grachev, A.; Korablev, M. P.; Hernandez-Blanco, J. A.; Munkhtsog, B.; Rosenbaum, B.; Rozhnov, V. V.; Rajabi, A. M.; Noori, H.; Armstrong, E. E.; Petrov, D.
10.1101/2023.12.14.571340 — evolutionary biology — Posted on 2023-12-15
2075 Gain efficiency with streamlined and automated data processing: Examples from high-throughput monoclonal antibody production
Kotowicz, M.; Fengler, S.; Kurkowsky, B.; Meyer-Berhorn, A.; Moretti, E.; Blersch, J.; Shumanska, M.; Schmidt, G.; Kreye, J.; van Hoof, S.; Sanchez-Sendin, E.; Reincke, M.; Krueger, L.; Pruess, H.; Denner, P.; Fava, E.; Stappert, D.
10.1101/2023.12.14.571214 — cell biology — Posted on 2023-12-15
2077 mTOR signaling controls the formation of smooth muscle cell-derived intimal fibroblasts during vasculitis.
Stock, A.; Parsons, S.; Hansen, J.; D'Silva, D. B.; Starkey, G.; Fayed, A.; Lim, X. Y.; D'Costa, R.; Gordon, C. L.; Wicks, I. P.
10.1101/2023.12.15.571811 — cell biology — Posted on 2023-12-15
2078 Fine-tuning Rpb4 phosphorylation modulates Rpb4/7 stoichiometry within yeast RNA polymerase II and regulates gene expression
Gonzalez-Jimenez, A.; Gonzalez-Jimenez, M. d. C.; Jordan-Pla, A.; Medina, I.; Alfonso, M. J.; Richard, S.; Fernandez-Tornero, C.; Choder, M.; Calvo, O.
10.1101/2023.12.15.571801 — molecular biology — Posted on 2023-12-15
2080 Pneumococcal Extracellular Vesicles Mediate Horizontal Gene Transfer via the Transformation Machinery
Werner Lass, S.; Camphire, S.; Smith, B. E.; Smith, R. A.; Prentice, J. A.; Yerneni, S. S.; Arun, A.; Bridges, A. A.; Rosch, J. W.; Conway, J. F.; Campbell, P.; Hiller, N. L.
10.1101/2023.12.15.571797 — microbiology — Posted on 2023-12-15
2083 Targeting HLA-E Positive Cancers with a Novel NKG2A/C Switch Receptor
Saetersmoen, M. L.; Kotchetkov, I.; Torralba-Raga, L.; Masilla-Soto, J.; Sohlberg, E.; Krokeide, S. Z.; Hammer, Q.; Sadelain, M.; Malmberg, K.-J.
10.1101/2023.12.14.571754 — immunology — Posted on 2023-12-15
2084 Engram Reactivation Mimics Cellular Signatures of Fear
Suthard, R. L.; Senne, R. A.; Buzharsky, M. D.; Diep, A. H.; Pyo, A. Y.; Ramirez, S.
10.1101/2023.12.14.571734 — neuroscience — Posted on 2023-12-15
2085 Prenatal exposure to valproic acid reduces synaptic δ-catenin levels and disrupts ultrasonic vocalization in neonates
Roh, S. H.; Mendez-Vazquez, H.; Sathler, M. F.; Doolittle, M. J.; Zaytseva, A.; Brown, H.; Sainsbury, M.; Kim, S.
10.1101/2023.12.14.571709 — neuroscience — Posted on 2023-12-15
2086 Neuroanatomical changes observed over the course of a human pregnancy
Pritschet, L.; Taylor, C. M.; Cossio, D.; Santander, T.; Grotzinger, H.; Faskowitz, J.; Handwerker, D. A.; Layher, E.; Chrastil, E. R.; Jacobs, E. G.
10.1101/2023.12.14.571688 — neuroscience — Posted on 2023-12-15
2087 Acute Neuropixels recordings in the marmoset monkey
Dotson, N. M.; Davis, Z. W.; Jendritza, P.; Reynolds, J. H.
10.1101/2023.12.14.571771 — neuroscience — Posted on 2023-12-15
2088 GSK3 inhibition reduces ECM production and prevents age-related macular degeneration-like pathology
DiCesare, S. M.; Ortega, A. J.; Collier, G. E.; Daniel, S.; Thompson, K. N.; McCoy, M. K.; Posner, B. A.; Hulleman, J. D.
10.1101/2023.12.14.571757 — neuroscience — Posted on 2023-12-15
2094 Single nucleus transcriptome of a "Super RV" shows increased insulin and angiogenesis signaling
Turaga, D.; Li, X.; Zhao, Y.; Tsai, C.-R.; Moreira, A.; Hickey, E.; Adachi, I.; Martin, J. F.
10.1101/2023.11.28.569092 — developmental biology — Posted on 2023-12-15
2095 Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje Cells
Zaman, T.; Vogt, D.; Prokop, J.; Alsabia, Q. A.; Simms, G.; Stafford, A.; Luikart, B.; Williams, M. R.
10.1101/2023.05.30.542885 — neuroscience — Posted on 2023-12-15
2097 Potassium dependent structural changes in the selectivity filter of HERG potassium channels
Lau, C. H.; Flood, E.; Hunter, M. J.; Williams-Noonan, B. J.; Corbett, K. M.; Ng, C.-A.; Bouwer, J. C.; Stewart, A. G.; Perozo, E.; Allen, T. W.; Vandenberg, J. I.
10.1101/2023.12.14.571769 — biophysics — Posted on 2023-12-15
2099 Penguin tracking data for effective conservation in marine spatial planning
Venegas-Li, R.; Chiaradia, A.; Schinagl, H.; Kato, A.; Ropert-Coudert, Y.; Possingham, H.; Reina, R. D.
10.1101/2023.12.14.571606 — ecology — Posted on 2023-12-15
2101 cAMP in budding yeast: a messenger for sucrose metabolism?
Botman, D.; Kanagasabapathi, S.; Rep, M. I.; Rossum, K. v.; Tutucci, E.; Teusink, B.
10.1101/2023.12.15.571809 — microbiology — Posted on 2023-12-15
2102 Non-canonical NF-κB signaling promotes intestinal inflammation by restraining the tolerogenic β-catenin-Raldh2 axis in dendritic cells
Deka, A.; Kumar, N.; Chawla, M.; Bhattacharya, N.; Ali, A. S.; Basu, S.; Bhawna, ; Madan, U.; Kumar, S.; Das, B.; Sengupta, D.; Awasthi, A.; Basak, S.
10.1101/2023.12.03.569755 — immunology — Posted on 2023-12-15
2105 Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway
Chen, J.; Zhao, B.; Li, T.; Dong, H.; Cheng, X.; Gong, W.; Wang, J.; Zhang, J.; Xin, G.; Yu, Y.; Lei, Y.; Black, J.; Li, Z.; Wen, H.
10.1101/2023.12.14.571787 — cancer biology — Posted on 2023-12-15
2106 Electro-Osmotic Flow Generation via a Sticky Ion Action
Mehrafrooz, B.; Yu, L.; Siwy, Z. S.; Wanunu, M.; Aksimentiev, A. S.
10.1101/2023.12.14.571673 — biophysics — Posted on 2023-12-15
2108 Airway epithelial cells as a novel intracellular host reservoir for Cryptococcus spores
Ortiz, S. C.; Fortune-Grant, R.; Davies, J.; May, R. C.; Drummond, R. A.; Bertuzzi, M.
10.1101/2023.12.14.571430 — microbiology — Posted on 2023-12-15
2110 Vinculin-Arp2/3 Interaction Inhibits Branched Actin Assembly to Control Cell Migration and Cell Cycle Progression
James, J.; Fokin, A. I.; Guschin, D. Y.; Wang, H.; Polesskaya, A.; Rubtsova, S. N.; Le Clainche, C.; Silberzan, P.; Gautreau, A. M.; Romero, S.
10.1101/2023.10.09.561480 — cell biology — Posted on 2023-12-15
2111 The cholesterol biosynthesis enzyme FAXDC2 couples Wnt/beta-catenin to RTK/MAPK signaling
Madan, B.; Wadia, S. R.; Patnaik, S.; Harmston, N. P.; Tan, E. J.; Tan, I. B.; Nes, D. W.; Petretto, E. G.; Virshup, D. M.
10.1101/2023.12.15.571793 — cancer biology — Posted on 2023-12-15
2112 Mechanisms of transcriptional regulation in Anopheles gambiae revealed by allele specific expression
Dyer, N. A.; Lucas, E. R.; Nagi, S. C.; McDermott, D. P.; Brenas, J. H.; Miles, A.; Clarkson, C. S.; Mawejje, H. D.; Wilding, C. S.; Halfon, M. S.; Asma, H.; Heinz, E.; Donnelly, M. J.
10.1101/2023.11.22.568226 — genetics — Posted on 2023-12-15
2117 Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma
Zhang, X.; Liu, Y.-Z.; Lan, R.; Liu, Y.; Pillarisetty, V. G.; Li, D.; Zhao, C. L.; Sarkar, S.; Liu, W.; Hanna, I.; Gupta, M.; Hajdu, C.; Melamed, J.; Widmer, J.; Allendorf, J.
10.1101/2023.10.26.564099 — cancer biology — Posted on 2023-12-15
2118 Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9
Eggers, A. R.; Chen, K.; Soczek, K. M.; Tuck, O. T.; Doherty, E. E.; Thornton, B. W.; Xu, B.; Trinidad, M. I.; Doudna, J. A.
10.1101/2023.12.14.571777 — molecular biology — Posted on 2023-12-15
2119 HELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination
Haji-Seyed-Javadi, R.; Koyen, A. E.; Rath, S. K.; Madden, M. Z.; Hou, Y.; Song, B. S.; Kenney, A. M.; Lan, L.; Yao, B.; Yu, D. S.
10.1101/2023.12.14.571747 — molecular biology — Posted on 2023-12-15
2122 Neoblast-like Stem Cells of Fasciola hepatica
McCusker, P.; Clarke, N. G.; Gardiner, E.; Armstrong, R.; McCammick, E. M.; McVeigh, P.; Robb, E.; Wells, D.; Nowak-Roddy, M.; Albaqami, A.; Mousley, A.; Coulter, J. A.; Harrington, J.; Marks, N. J.; Maule, A. G.
10.1101/2023.12.15.571799 — molecular biology — Posted on 2023-12-15
2123 Pan-azole- and multi-fungicide-resistant Aspergillus fumigatus is widespread in the United States
Celia-Sanchez, B.; Mangum, B.; Gomez, L. L.; Wang, C.; Shuman, B.; Brewer, M. T.; Momany, M.
10.1101/2023.12.14.571763 — microbiology — Posted on 2023-12-15
2124 Effective seed sterilization methods require optimization across maize genotypes
Parnell, J. J.; Pal, G.; Awan, A.; Vintila, S.; Houdinet, G.; Hawkes, C. V.; Balint-Kurti, P.; Wagner, M. R.; Kleiner, M.
10.1101/2023.12.14.571779 — microbiology — Posted on 2023-12-15
2125 RNA-guided RNA silencing by an Asgard archaeal Argonaute
Bastiaanssen, C.; Ugarte, P. B.; Kim, K.; Feng, Y.; Finocchio, G.; Anzelon, T. A.; Kostlbacher, S.; Tamarit, D. C.; Ettema, T. J. G.; Jinek, M.; MacRae, I. J.; Joo, C.; Swarts, D. C.; Wu, F.
10.1101/2023.12.14.571608 — microbiology — Posted on 2023-12-15
2128 Highly pathogenic avian influenza H5N1 virus infections in pinnipeds and seabirds in Uruguay: a paradigm shift to virus transmission in South America
Tomas, G.; Marandino, A.; Panzera, Y.; Rodriguez, S.; Wallau, G. d. L.; Dezordi, F.; Perez, R.; Bassetti, L.; Negro, R.; Williman, J.; Uriarte, V.; Grazioli, F.; Leizagoyen, C.; Riveron, S.; Coronel, J.; Bello, S.; Paez, E.; Lima, M.; Mendez, V.; Perez, R.
10.1101/2023.12.14.571746 — microbiology — Posted on 2023-12-15
2129 The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity
Kalkreuter, E.; Kautsar, S. A.; Yang, D.; Teijaro, C. N.; Bader, C. D.; Fluegel, L. L.; Davis, C. M.; Simpson, J. R.; Steele, A. D.; Gui, C.; Meng, S.; Li, G.; Viehrig, K.; Ye, F.; Su, P.; Kiefer, A. F.; Lauterbach, L.; Nichols, A.; Cepeda, A. J.; Yan, W.; Fan, B.; Jiang, Y.; Adhikari, A.; Zheng, C.-J.; Shen, B.
10.1101/2023.12.14.571759 — microbiology — Posted on 2023-12-15
2130 GlnA3Mt is able to glutamylate spermine but it is not essential for the detoxification of spermine in Mycobacterium tuberculosis
Krysenko, S.; Emani, C. S.; Bäuerle, M.; Oswald, M.; Kulik, A.; Meyners, C.; Hillemann, D.; Merker, M.; Wohlers, I.; Hausch, F.; Brötz-Oesterhelt, H.; Mitulski, A.; Reiling, N.; Wohlleben, W.
10.1101/2023.12.14.571729 — microbiology — Posted on 2023-12-15
2132 The Kinetochore Protein KNL-1 Regulates the Actin Cytoskeleton to Control Dendrite Branching
Green, M.; Domingos, H. A.; Ouzounidis, V. R.; Finlayson, C.; Prevo, B.; Cheerambathur, D. K.
10.1101/2023.03.29.534821 — neuroscience — Posted on 2023-12-15
2134 Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments
Lang, S.; Fletcher, D. A.; Petit, A.-P.; Luise, N.; Fyfe, P. K.; Zuccotto, F.; Porter, D.; Hope, A.; Bellany, F.; Kerr, C.; MacKenzie, C. J.; Wyatt, P. G.; Gray, D. W.
10.1101/2023.12.01.569544 — pharmacology and toxicology — Posted on 2023-12-15
2135 Structural basis of connexin-36 gap junction channel inhibition
Ding, X.; Aureli, S.; Vaithia, A.; Lavriha, P.; Schuster, D.; Khanppnavar, B.; Li, X.; Blum, T. B.; Picotti, P.; Gervasio, F. L.; Korkhov, V. M.
10.1101/2023.12.09.570920 — biophysics — Posted on 2023-12-15
2136 Conformational Space Profile Enhances Generic Molecular Representation Learning
Wang, L.; Wang, S.; Yang, H.; Li, S.; Wang, X.; Zhou, Y.; Tian, S.; Liu, L.; Bai, F.
10.1101/2023.12.14.571629 — bioinformatics — Posted on 2023-12-15
2140 CRISPR-Cas9 Engineered Extracellular Vesicles for the Treatment of Dominant Progressive Hearing Loss
Pan, X.; Huang, P.; Ali, S.; Renslo, B.; Hutchinson, T. E.; Erwin, N.; Greenberg, Z. F.; Ding, Z.; Li, Y.; Warnecke, A.; Fernandez, N. E.; Staecker, H.; He, M.
10.1101/2023.09.14.557853 — bioengineering — Posted on 2023-12-15
2142 A Fluorogenic-Based Assay to Measure Chaperone-Mediated Autophagic Activity in Cells and Tissues
Jonnavithula, A.; Tandar, M.; Umar, M.; Orton, S. N.; Woodrum, M. C.; Mookherjee, S.; Boudina, S.; Symons, J. D.; Ghosh, R.
10.1101/2023.12.14.571785 — biochemistry — Posted on 2023-12-15
2144 In-vivo Therapeutic Evaluation of the Wound Healing Potential of Ethanolic Extract of Trichilia heudelotii Leaves in Wistar Rats
Victoria, A. G.; Hassan, J. T.; Toyin, Y. M.; Oyetunji, O. A.; Aborode, A. T.; Alexiou, A.; Mukerjee, N.; Maitra, S.; Papadakis, M.; Rahman, M. H.
10.1101/2023.12.14.571768 — biochemistry — Posted on 2023-12-15
2145 The Horizontal Ladder Test (HLT) protocol: A novel, optimized, and reliable means of assessing motor coordination in Sus scrofa domesticus
Liu, X.; Gutierrez, A. G.; Vega, A.; Willms, J. O.; Driskill, J.; Pathagani, P.; Sanchez, J.; Aguilera, M.; Backus, B.; Bailoo, J. D.; Bergeson, S. E.
10.1101/2023.12.13.571517 — animal behavior and cognition — Posted on 2023-12-15
2147 Integrative analyses of convergent adaptation in sympatric extremophile fishes
Greenway, R. S.; De-Kayne, R.; Brown, A. P.; Camarillo, H.; Delich, C.; McGowan, K. L.; Nelson, J. T.; Arias-Rodriguez, L.; Kelley, J. L.; Tobler, M.
10.1101/2021.06.28.450104 — evolutionary biology — Posted on 2023-12-15
2148 DLG1 functions upstream of SDCCAG3 and IFT20 to control ciliary targeting of polycystin-2
Rezi, C. K.; Aslanyan, M.; Diwan, G. D.; Cheng, T.; Chamlali, M.; Junger, K.; Anvarian, Z.; lorentzen, e.; Pauly, K. B.; Bahadori, Y.; Fernandes, E. F.; Qian, F.; Tosi, S.; Christensen, S. T.; Pedersen, S. F.; Stromgaard, K.; Russell, R. B.; Miner, J. H.; Mahjoub, M. R.; Boldt, K.; Roepman, R.; Pedersen, L. B.
10.1101/2023.11.10.566524 — cell biology — Posted on 2023-12-15
2150 Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila
Eichler, K.; Hampel, S.; Alejandro, A.; Calle, S.; Santana, A.; Kmecova, L.; Blagburn, J. M.; Hoopfer, E. D.; Seeds, A. M.
10.1101/2023.02.11.528119 — neuroscience — Posted on 2023-12-15
2152 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2023-12-15
2153 Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.
Conn, K.; Milton, L. K.; Huang, K.; Munguba, H.; Ruuska, J.; Lemus, M. B.; Greaves, E.; Homman-Ludiye, J.; Oldfield, B. J.; Foldi, C. J.
10.1101/2023.12.12.571374 — neuroscience — Posted on 2023-12-15
2156 TML1 AND TML2 SYNERGISTICALLY REGULATE NODULATION BUT NOT ARBUSCULAR MYCORRHIZA IN MEDICAGO TRUNCATULA
Chaulagain, D.; Schnabel, E.; Lin, E. X.; Garcia, R. R.; Noorai, R. E.; Müller, L. M.; Frugoli, J. A.
10.1101/2023.12.07.570674 — molecular biology — Posted on 2023-12-14
2159 Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates
Wilson, R. L.; Kropp Schmidt, J.; Davenport, B. N.; Ren, E.; Keding, L. T.; Shaw, S.; Schotzko, M. L.; Antony, K.; Simmons, H. A.; Golos, T.; Jones, H.
10.1101/2023.06.16.545278 — physiology — Posted on 2023-12-14
2160 MHC-Fine: Fine-tuned AlphaFold for Precise MHC-Peptide Complex Prediction
Glukhov, E.; Kalitin, D.; Stepanenko, D.; Zhu, Y.; Nguyen, T.; Jones, G.; Simmerling, C.; Mitchell, J. C.; Vajda, S.; Dill, K. A.; Padhorny, D.; Kozakov, D.
10.1101/2023.11.29.569310 — bioinformatics — Posted on 2023-12-14
2162 Measuring Neuronal Avalanches to inform Brain-Computer Interfaces
Corsi, M.-C.; Sorrentino, P.; Schwartz, D.; George, N.; Gollo, L.; Chevallier, S.; Hugueville, L.; Kahn, A. E.; Dupont, S.; Bassett, D. S.; Jirsa, V.; De Vico Fallani, F.
10.1101/2022.06.14.495887 — neuroscience — Posted on 2023-12-14
2163 Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer
Lancaster, N. M.; Sinitcyn, P.; Forny, P.; Peters-Clarke, T. M.; Fecher, C.; Smith, A. J.; Shishkova, E.; Arrey, T. N.; Pashkova, A.; Robinson, M. L.; Arp, N.; Fan, J.; Hansen, J.; Galmozzi, A.; Serrano, L. R.; Westphall, M. S.; Stewart, H.; Hock, C.; Damoc, E.; Pagliarini, D. J.; Zabrouskov, V.; Coon, J. J.
10.1101/2023.11.21.568149 — systems biology — Posted on 2023-12-14
2164 NK cells contribute to resistance to anti-PD1 therapy in immune-excluded melanomas
Landeloos, E.; Pozniak, J.; Roda, N.; de Visscher, A.; Antoranz, A.; van Herck, Y.; Bervoets, G.; Bosisio, F. M.; Boecxstaens, V.; Bassez, A.; Lambrechts, D.; Matthys, P.; Bechter, O.; Marine, J.-C.
10.1101/2023.12.14.571631 — cancer biology — Posted on 2023-12-14
2167 Scm6A: A fast and low-cost method for quantifying m6A modifications at the single-cell level
Li, Y.; Li, J.; Li, W.; Liang, S.; Wei, W.; Chu, J.; Lai, J.; Lin, Y.; Chen, H.; Su, J.; Hu, X.; Wang, G.; Meng, J.; Jiang, J.; Ye, L.; An, S.
10.1101/2023.12.14.571511 — bioinformatics — Posted on 2023-12-14
2169 Conformational Space Profile Enhances Generic Molecular Representation Learning
Wang, L.; Wang, S.; Yang, H.; Li, S.; Wang, X.; Zhou, Y.; Tian, S.; Liu, L.; Bai, F.
10.1101/2023.12.14.571629 — bioinformatics — Posted on 2023-12-14
2170 A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia
Markov, N. S.; Ren, Z.; Senkow, K. J.; Grant, R. A.; Gao, C. A.; Malsin, E. S.; Sichizya, L.; Kihshen, H.; Helmin, K. A.; Jovisic, M.; Arnold, J. M.; Perez-Leonor, X. G.; Abdala-Valencia, H.; Swaminathan, S.; Nwaezeapu, J.; Kang, M.; Rasmussen, L.; Ozer, E. A.; Lorenzo-Redondo, R.; Hultquist, J. F.; Simons, L.; Rios-Guzman, E.; Misharin, A. V.; Wunderink, R. G.; Budinger, G. S.; Singer, B. D.; Morales-Nebreda, L.; The NU SCRIPT Investigators,
10.1101/2023.12.13.571479 — systems biology — Posted on 2023-12-14
2171 Whole group tracking reveals that relatedness drives consistent subgrouping patterns in white-nosed coatis
Grout, E. M.; Ortega, J.; Minasandra, P.; Quin, M. J.; Crofoot, M. C.; Strandburg-Peshkin, A.; Hirsch, B. T.
10.1101/2023.12.14.571650 — animal behavior and cognition — Posted on 2023-12-14
2179 Fructose-1-kinase has pleiotropic roles in Escherichia coli
Weeramange, C.; Menjivar, C.; O'Neil, P. T.; El Qaidi, S.; Harrison, K. S.; Meinhardt, S.; Bird, C. L.; Sreenivasan, S.; Fenton, A. W.; Hefty, P. S.; Hardwidge, P. R.; Bose, J. L.; Swint-Kruse, L.
10.1101/2023.12.14.571569 — microbiology — Posted on 2023-12-14
2181 Airway epithelial cells as a novel intracellular host reservoir for Cryptococcus spores
Ortiz, S. C.; Fortune-Grant, R.; Davies, J.; May, R. C.; Drummond, R. A.; Bertuzzi, M.
10.1101/2023.12.14.571430 — microbiology — Posted on 2023-12-14
2182 Temporal Changes in Innate and Adaptive Immunity During Sepsis as Determined by ELISpot
Walton, A. H.; Hotchkiss, R. S.; Osborne, D.; Unsinger, J.; Han, E. H.; Sheets, L.; Mazer, M. B.; Remy, K. E.; Griffith, T. S.; Rao, M.; Badovinac, V. P.; Brakenridge, S. C.; Turnbull, I.; Efron, P. A.; Moldawer, L. L.; Calwell, C. C.
10.1101/2023.12.14.571668 — immunology — Posted on 2023-12-14
2184 Gene replacement therapy for Lafora disease in the Epm2a-/- mouse model
Zafra-Puerta, L.; F. Burgos, D.; Iglesias-Cabeza, N.; Gonzalez-Fernandez, J.; Sanchez-Martin, G.; Sanchez, M. P.; Serratosa, J. M.
10.1101/2023.12.14.571636 — neuroscience — Posted on 2023-12-14
2185 Striatal dopamine reflects individual long-term learning trajectories
Liebana Garcia, S.; Laffere, A.; Toschi, C.; Schilling, L.; Podlaski, J.; Fritsche, M.; Zatka-Haas, P.; Li, Y.; Bogacz, R.; Saxe, A.; Lak, A.
10.1101/2023.12.14.571653 — neuroscience — Posted on 2023-12-14
2187 Memory reactivation during sleep does not act holistically on object memory
Siefert, E. M.; Uppuluri, S.; Mu, J.; Tandoc, M. C.; Antony, J. W.; Schapiro, A. C.
10.1101/2023.12.14.571683 — neuroscience — Posted on 2023-12-14
2192 Modulation of cell differentiation and growth dynamics underlie the shift from bud protection to light capture in cauline leaves
Kierzkowski, D.; Le Gloanec, C.; Gomez-Felipe, A.; Alimchandani, V.; Branchini, E.; Routier-Kierzkowska, A.-L.
10.1101/2023.12.13.571562 — plant biology — Posted on 2023-12-14
2193 DNA binding and bridging by human CtIP in the healthy and diseased states
Lokanathan Balaji, S.; De Braganca, S.; Balaguer-Perez, F.; Northall, S.; Wilkinson, O. J.; Aicart-Ramos, C.; Sobott, F.; Seetaloo, N.; Moreno-Herrero, F.; Dillingham, M. S.
10.1101/2023.12.14.571649 — biochemistry — Posted on 2023-12-14
2197 Path analysis reveals combined winter climate and pollution effects on the survival of a marine top predator
Layton-Matthews, K.; Erikstad, K. E.; Sandvik, H.; Ballesteros, M.; Hodges, K.; Mesquita, M. d. S.; Reiertsen, T. K.; Yoccoz, N. G.; Bustnes, J. O.
10.1101/2023.12.14.571445 — ecology — Posted on 2023-12-14
2198 Inactivation of the Niemann Pick C1 cholesterol transporter 1 (NPC1) restricts SARS-CoV-2 infection
La Rosa, P.; Tiberi, J.; Palermo, E.; Tiano, S.; Cortese, M.; Hiscott, J.; Fiorenza, M. T.
10.1101/2023.12.13.571570 — cell biology — Posted on 2023-12-14
2199 Causal role of the angular gyrus in insight-driven memory reconfiguration
Grob, A.-M.; Heinbockel, H.; Milivojevic, B.; Doeller, C.; Schwabe, L.
10.1101/2023.08.18.553803 — neuroscience — Posted on 2023-12-14
2202 Determinants of cerebral blood flow and arterial transit time in healthy older adults
Feron, J.; Segaert, K.; Rahman, F.; Fosstveit, S.; Joyce, K. E.; Gilani, A.; Lohne-Seiler, H.; Bernsten, S.; Mullinger, K. J.; Lucas, S. J. E.
10.1101/2023.12.13.571578 — physiology — Posted on 2023-12-14
2203 Transcriptional Isoforms of NAD+ Kinase regulate oxidative stress resistance and melanoma metastasis
Cascio, G.; Aguirre, K.; Church, K.; Hughes, R. O.; Nease, L.; Licona, D. Q.; Delclaux, I.; Zerhouni, M.; Piskounova, E.
10.1101/2023.02.02.526506 — cancer biology — Posted on 2023-12-14
2206 Deep MALDI-MS Spatial Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy
Gruber, L.; Schmidt, S.; Enzlein, T.; Vo, H. G.; Cairns, J. L.; Ucal, Y.; Keller, F.; Abu Sammour, D.; Rudolf, R.; Eckhardt, M.; Iakab, S. A.; Bindila, L.; Hopf, C.
10.1101/2023.12.14.571637 — biochemistry — Posted on 2023-12-14
2209 New avenues for potentially seeking microbial responses to climate change beneath Antarctic ice shelves
Martinez-Garcia, M.; Llorenc Vicedo, A.; Lluesma-Gomez, M.; Zeising, O.; Kleiner, T.; Freitag, J.; Martinez-Hernandez, F.; Wilhelms, F.
10.1101/2023.12.13.571508 — microbiology — Posted on 2023-12-14
2211 Mitochondrial Biomarkers and Metabolic Syndrome in Bipolar Disorder
Zachos, K. A.; Choi, J.; Godin, O.; Chernaga, T.; Kwak, H. A.; jung, J. H.; Aouizerate, B.; Aubin, V.; Bellivier, F.; Belzeaux, R.; Courtet, P.; Dubertret, C.; Etain, B.; Haffen, E.; lefrere, a.; Llorca, P.-M.; Olie, E.; Polsan, M.; Samalin, L.; Schwan, R.; Roux, P.; Barau, C.; Richard, J.-R.; Tamouza, R.; Leboyer, M.; Andreazza, A.
10.1101/2023.12.13.571526 — neuroscience — Posted on 2023-12-14
2212 Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming
Dourson, A. J.; Fadaka, A. O.; Warshak, A. M.; Paranjpe, A.; Weinhaus, B.; Queme, L. F.; Hofmann, M. C.; Evans, H. M.; Donmez, O. A.; Forney, C.; Weirauch, M. T.; Kottyan, L. T.; Lucas, D.; Deepe, G. S.; Jankowski, M. P.
10.1101/2023.02.13.528015 — neuroscience — Posted on 2023-12-14
2213 VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism
Kumari, R.; Ponte, M.; Franczak, E.; Prom, J.; O'Neil, M.; Sardiu, M. E.; Lutkewitte, A.; Shankar, K.; Morris, E. M.; Thyfault, J.
10.1101/2023.12.14.571644 — physiology — Posted on 2023-12-14
2214 ERG1a K+ Channel Increases Intracellular Calcium Concentration through Modulation of Calsequestrin 1 in C2C12 Myotubes
Hockerman, G. H.; Pratt, E.; Guha, S.; LaVigne, E.; Whitmore, C.; Khader, O.; McClure, N.; Zampieri, S.; Koran, J.; Wang, W.-H.; Pond, A. L.
10.1101/2023.12.04.569937 — physiology — Posted on 2023-12-14
2215 ATOM-1: A Foundation Model for RNA Structure and Function Built on Chemical Mapping Data
Boyd, N.; Anderson, B. M.; Townshend, B.; Chow, R.; Stephens, C. J.; Rangan, R.; Kaplan, M.; Corley, M.; Tambe, A.; Ido, Y.; Yukich, J.; Tcheau, T.; Abdeldayem, A.; Ferns, G.; Patel, H.; Barman, S.; Schleck, A.; Sanborn, A. L.; Eismann, S.; Townshend, R. J. L.
10.1101/2023.12.13.571579 — bioinformatics — Posted on 2023-12-14
2217 Multivalent DNA-encoded lectins on phage enable detecting compositional glycocalyx differences
Lima, G. M.; Chenarboo, Z. J.; Sojitra, M.; Sarkar, S.; Carpenter, E. J.; Yang, C. Y.-L.; Schmidt, E.; Lai, J.; Atrazhev, A.; Yazdan, D.; Peng, C.; Volker, E. A.; Ho, R.; Monteiro, G.; Lai, R.; Mahal, L. K.; Macauley, M. S.; Derda, R.
10.1101/2023.12.13.571601 — biochemistry — Posted on 2023-12-14
2221 Phylogenomics resolves key relationships in Rumex and uncovers a dynamic history of independently evolving sex chromosomes
Hibbins, M. S.; Rifkin, J. L.; Choudhury, B. I.; Voznesenka, O.; Sacchi, B. M.; Yuan, M.; Gong, Y.; Barrett, S. C. H.; Wright, S. I.
10.1101/2023.12.13.571571 — evolutionary biology — Posted on 2023-12-14
2224 Interplay between m6A modification and overall transcripts quantity: Impacts on mRNA composition in plant stress granules
Kubiak, D. J.; Szczesniak, M. W.; Ostrowska, K.; Bielewicz, D.; Bhat, S. S.; Niedojadlo, K.; Szweykowska-Kulinska, Z.; Jarmolowski, A.; Fray, R. G.; Niedojadlo, J.
10.1101/2023.12.14.569339 — cell biology — Posted on 2023-12-14
2225 Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway and dependent on low IGF1R level
Joergensen, S. H.; Emdal, K. B.; Pedersen, A.-K.; Axelsen, L. N.; Kildegaard, H. F.; Damozay, D.; Pedersen, T. A.; Groenborg, M.; Slaaby, R.; Nielsen, P. K.; Olsen, J. V.
10.1101/2023.12.14.571674 — cell biology — Posted on 2023-12-14
2226 PI4KIII3β inhibition reduces rhinovirus associated cell shedding and ciliary dysfunction
Velkova, S.; Petris, A.; Lee, D.; Cardinale, D.; Moulding, D.; Williamson, R.; Beinke, S.; Grace, K.; Hessel, E.; Belyaev, N.; Hoegg, T.; Hurst, J.; Smyth, R.; Smith, C.; Freestone, P.; O'Callaghan, C.
10.1101/2023.12.14.571686 — cell biology — Posted on 2023-12-14
2227 Sperm motility restoration in mice suffering from oligo-astheno-teratozoospermia by in vivo injection and electroporation of naked mRNA
Vilpreux, C.; Martinez, G.; Court, M.; Appaix, F.; Duteyrat, J. L.; Henry, M.; Vollaire, J.; Ayad, C.; Yavuz, A.; De Macedo, L.; Chevalier, G.; Lambert, E.; Ahmed Conte, S.; Giordani, E.; Josserand, V.; Brocard, J.; Coutton, C.; Verrier, B.; Ray, P. F.; Loeuillet, C.; Arnoult, C.; Escoffier, J.
10.1101/2023.12.12.571239 — molecular biology — Posted on 2023-12-14
2228 Clustered Regularly Interspaced Short Palindromic Repeats-Cas system regulates Salmonella virulence
Marathe, S. A.; Sharma, N.; Das, A.; Sethi, P.; Nair, A. V.; Chakravortty, D.; Negi, V. D.
10.1101/2023.12.12.571267 — microbiology — Posted on 2023-12-14
2231 Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania
Hiza, H.; Michaela, Z.; Hella, J.; Arbues, A.; Sasamalo, M.; Borrell, S.; Xu, Z. M.; Ross, A.; Brites, D.; Fellay, J.; Reither, K.; Gagneux, S.; Portevin, D.
10.1101/2023.12.13.571507 — microbiology — Posted on 2023-12-14
2232 Phylogenomic and phenotypic analyses highlight the diversity of antibiotic resistance and virulence in both human and non-human Acinetobacter baumannii
Sykes, E.; Mateo-Estrada, V.; Engelberg, R.; Muzaleva, A.; Zhanel, G.; Dettman, J.; Chapados, J. T.; Gerdis, S.; Akineden, O.; KHAN, I. U. H.; Castillo-Ramirez, S.; Kumar, A.
10.1101/2023.12.13.571483 — microbiology — Posted on 2023-12-14
2233 Single cell analysis reveals CD45RClow/-TNFR2+CD29lowCD8+ Tregs with superior activity
Serazin, C.; Flippe, L.; Streitz, M.; Wendering, D.-J.; Schlickeiser, S.; Heinrich, F.; Durek, P.; Guerra, G. M.; Lehmann, K.; Mashreghi, M.-F.; Wajant, H.; Volk, H.-D.; Anegon, I.; David, L.; Bezie, S.; Guillonneau, C.
10.1101/2023.12.13.571475 — immunology — Posted on 2023-12-14
2234 Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.
Wang, Y.; Hollingsworth, L. R.; Sangare, L. O.; Paredes-Santos, T.; Krishnamurthy, S.; Penn, B.; Wu, H.; Saeij, J. P. J.
10.1101/2023.12.13.571530 — immunology — Posted on 2023-12-14
2235 Systemic Sclerosis dermal fibroblast exosomes trigger a Type 1 interferon response in keratinocytes through the TBK/JAK/STAT signalling axis
Bryon, J.; Wasson, C. W.; Koeppen, K.; Chandler, F.; Willis, L. F.; Klein, E.; Zeqiraj, E.; Ross, R. L.; Del Galdo, F.
10.1101/2023.12.14.570365 — immunology — Posted on 2023-12-14
2238 TEMPORAL PATTERN OF SYNAPTIC ACTIVATION DIFFERENTIALLY AFFECTS PLASTICITY IN NORMAL AND INJURED BRAIN
Fischer, Q. S.; Kalikulov, D.; Viana Di Prisco, G.; Williams, C. A.; Baldwin, P. R.; Friedlander, M. J.
10.1101/2023.12.13.571587 — neuroscience — Posted on 2023-12-14
2239 Liver Protects Cytoarchitecture, Neuron Viability and Electrocortical Activity in Post-Cardiac Arrest Brain Injury
Guo, Z.; Yin, M.; Sun, C.; Xu, G.; Wang, T.; Jia, Z.; Zhang, Z.; Zhu, C.; Zheng, D.; Wang, L.; Huang, S.; Liu, D.; Zhang, Y.; Xie, R.; Gao, N.; Yu, P.; Zhan, L.; He, S.; Zhu, Y.; Li, Y.; Nashan, B.; Andrea, S.; Xu, J.; Zhao, Q.; He, X.
10.1101/2023.12.13.571604 — neuroscience — Posted on 2023-12-14
2240 Aerosolized α1 adrenoreceptor antagonism does not affect experimentally induced lung fibrosis in animal models
Ghincea, A.; Perry, C.; Liu, A.; McGovern, J.; Sheeline, Y.; Peng, X. Y.; Genta, I.; Barnthaler, T.; Herzog, E.; Sun, H.
10.1101/2023.12.12.571378 — pathology — Posted on 2023-12-14
2246 Cholesterol modulates the human FPN1 iron export function in plasma membrane liquid-ordered microdomains
Debbiche, R.; Ka, C.; Gourlaouen, I.; Maestri, S.; Uguen, K.; Jaffres, P.-A.; Callebaut, I.; Le Gac, G.
10.1101/2023.12.14.571614 — biochemistry — Posted on 2023-12-14
2247 Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes
Bergin, S. A.; Doorley, L. A.; Rybak, J.; Wolfe, K. H.; Butler, G.; Cuomo, C. A.; Rogers, P. D.
10.1101/2023.12.13.571446 — genomics — Posted on 2023-12-14
2249 Investigating structural variant, indel and single nucleotide polymorphism differentiation between locally adapted Atlantic salmon populations
Lecomte, L.; Arnyasi, M.; Ferchaud, A.-L.; Kent, M.; Lien, S.; Stenlokk, K.; Sylvestre, F.; Merot, C.; Bernatchez, L.
10.1101/2023.09.12.557169 — genomics — Posted on 2023-12-14
2250 A Comparative Analysis of Imaging-Based Spatial Transcriptomics Platforms
Cook, D. P.; Jensen, K. B.; Wise, K.; Roache, M. J.; Segato Dezem, F.; Ryan, N. K.; Zamojski, M.; Vlachos, I.; Knott, S. R.; Butler, L. M.; Wrana, J. L.; Banovich, N.; Plummer, J. T.; Martelotto, L. G.
10.1101/2023.12.13.571385 — genomics — Posted on 2023-12-14
2251 Phylogenomic Insights into the Evolution and Origin of Nematoda
Qing, X.; Zhang, Y. M.; Sun, S.; Ahmed, M.; Lo, W.-S.; Bert, W.; Holovachov, O.; Li, H.
10.1101/2023.12.13.571554 — genomics — Posted on 2023-12-14
2252 Deep Divergences Among Inconspicuously Colored Clades of Epipedobates Poison Frogs
Lopez-Hervas, K.; Santos, J. C.; Ron, S. R.; Betancourth-Cundar, M.; Cannatella, D. C.; Tarvin, R. D.
10.1101/2023.06.29.547117 — evolutionary biology — Posted on 2023-12-14
2254 Cities as parasitic amplifiers? Malaria prevalence and diversity in great tits along an urbanization gradient
Caizergues, A. E.; Robira, B.; Perrier, C.; Jeanneau, M.; Berthomieu, A.; Perret, S.; Gandon, S.; Charmantier, A.
10.1101/2023.05.03.539263 — ecology — Posted on 2023-12-14
2258 Molecular Speciation of Cyathostomins From Horses In Ireland
Byrne, O.; Gangotia, D.; Kiser, L.; McSweeney, D.; Lamb, B.-R.; O'Neill, F.; Dunne, S.; Boxall, O.; Zintl, A.; Walshe, N.; Mulcahy, G.
10.1101/2023.12.13.571572 — molecular biology — Posted on 2023-12-14
2259 Cyanobacterial sigma factor controls biofilm-promoting genes through intra- and intercellular pathways
Suban, S.; Yemini, S.; Shor, A.; Ben-Asher, H. W.; Yaron, O.; Lampert, S.; Sendersky, E.; Golden, S. S.; Schwarz, R.
10.1101/2023.12.14.570974 — microbiology — Posted on 2023-12-14
2260 The type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful symbiosis with Glycine max cv Pekin
Reyes-Perez, P.; Jimenez-Guerrero, I.; Sanchez-Reina, A.; Civantos, C.; Moreno-de Castro, N.; Bernal, P.; Perez-Montano, F.
10.1101/2023.12.14.571490 — microbiology — Posted on 2023-12-14
2261 Small molecule inhibitor binds to NLRP3 and prevents inflammasome activation
Lackner, A.; Cabral, J. E.; Qiu, Y.; Zhou, H.; Leonidas, L.; Pham, M. A.; Macapagal, A.; Lin, S.; Armanus, E.; McNulty, R.
10.1101/2023.12.13.571573 — immunology — Posted on 2023-12-14
2262 Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction
Onos, K. D.; Lin, P. B.; Pandy, R. S.; Persohn, S. A.; Burton, C. P.; Miner, E. W.; Eldridge, K.; Foley, K. E.; Howell, G. R.; Territo, P. R.
10.1101/2023.12.13.571584 — neuroscience — Posted on 2023-12-14
2264 Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS
Comaduran, M. F.; Minotti, S.; Jacob-Tomas, S.; Rizwan, J.; Larochelle, N.; Robitaille, R.; Sephton, C. F.; Vera, M.; Nalbantoglu, J. N.; Durham, H. D.
10.1101/2023.12.13.571549 — neuroscience — Posted on 2023-12-14
2265 Prefrontal dynamics and encoding of flexible rule switching
Nigro, M.; Silva Tortorelli, L.; Dinh, K.; Garad, M.; Zlebnik, N.; Yang, H.
10.1101/2023.12.13.571356 — neuroscience — Posted on 2023-12-14
2266 Targeting LOXL2 Improves Arterial Stiffness and Function in Angiotensin II-induced Hypertension in Males but not Females
Santhanam, L.; Wang, H.; Yus, M. M.; Brady, T.; Choi, R.; Nandakumar, K.; Smith, L.; Jang, R.; Wodu, B. P.; Almodiel, D.; Stoddart, L.; Kim, D.-H.; Steppan, J.
10.1101/2023.12.13.571541 — physiology — Posted on 2023-12-14
2267 ROR2 regulates cellular plasticity in pancreatic neoplasia and adenocarcinoma
Benitz, S.; Steep, A.; Nasser, M.; Preall, J.; Mahajan, U. M.; McQuithey, H.; Loveless, I.; Davis, E. T.; Wen, H.-J.; Long, D. W.; Metzler, T.; Zwernik, S.; Louw, M.; Rempinski, D.; Salas-Escabillas, D.; Brender, S.; Song, L.; Huang, L.; Zhang, Z.; Steele, N.; Regel, I.; Bednar, F.; Crawford, H. C.
10.1101/2023.12.13.571566 — cancer biology — Posted on 2023-12-14
2268 Integrin Mechanosensing relies on Pivot-clip Mechanism to Reinforce Cell Adhesion
Montes, A.; Barroso, A.; Wang, W.; O'Connell, G.; Buganza Tepole, A.; Mofrad, M.
10.1101/2023.12.13.571593 — biophysics — Posted on 2023-12-14
2270 Ensemble-based design of tau to inhibit aggregation while preserving biological activity.
Bali, S.; Singh, R.; Wydorski, P. M.; Wosztyl, A.; Perez, V. A.; chen, d.; Rizo, J.; Joachimiak, L. A.
10.1101/2023.12.13.571598 — biophysics — Posted on 2023-12-14
2271 Personalized Pangenome References
Siren, J.; Eskandar, P.; Ungaro, M. T.; Hickey, G.; Eizenga, J. M.; Novak, A. M.; Chang, X.; Chang, P.-C.; Kolmogorov, M.; Carroll, A.; Monlong, J.; Paten, B.
10.1101/2023.12.13.571553 — bioinformatics — Posted on 2023-12-14
2273 Recombine and succeed: a story of Cry toxins to expand the host range
Shikov, A. E.; Alagov, R. O.; Nizhnikov, A. A.; Belousova, M. E.; Antonets, K. S.
10.1101/2023.12.13.571466 — bioinformatics — Posted on 2023-12-14
2275 Closure of the gamma-tubulin ring complex by CDK5RAP2 activates microtubule nucleation
Xu, Y.; Munoz-Hernandez, H.; Krutyholowa, R.; Marxer, F.; Cetin, F.; Wieczorek, M.
10.1101/2023.12.14.571518 — biochemistry — Posted on 2023-12-14
2277 How to barcode (almost all) freshwater biodiversity
Tournayre, O.; Tian, H.; Lougheed, D. R.; Windle, M. J. S.; Lambert, S.; Carter, J.; Sun, Z.; Ridal, J.; Wang, Y.; Cumming, B. F.; Arnott, S. E.; Lougheed, S. C.
10.1101/2023.12.13.571596 — ecology — Posted on 2023-12-14
2278 Human Trophoblast Stem Cells Restrict Human Cytomegalovirus Replication
Rollman, T. B.; Berkebile, Z. W.; Okae, H.; Bardwell, V. J.; Gearhart, M. D.; Bierle, C. J.
10.1101/2023.12.13.571456 — microbiology — Posted on 2023-12-14
2279 Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors
Johnston, A. C.; Alicea, G. M.; Lee, C. C.; Patel, P. V.; Hanna, E. A.; Vaz, E.; Forjaz, A.; Wan, Z.; Nair, P. R.; Lim, Y.; Chen, T.; Du, W.; Kim, D.; Nichakawade, T. D.; Rebecca, V. W.; Bonifant, C. L.; Fan, R.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.
10.1101/2023.12.13.571595 — immunology — Posted on 2023-12-14
2280 Stress-induced c-fos expression in the medial prefrontal cortex of male rats differentially involves the main glial cell phenotypes
Aguilar-Delgadillo, A.; Cruz-Mendoza, F.; Luquin-de Anda, S.; Ruvalcaba-Delgadillo, Y.; Jauregui-Huerta, F.
10.1101/2023.12.13.571548 — neuroscience — Posted on 2023-12-14
2282 Transcriptional correlates of cocaine-associated learning in striatal ARC ensembles.
Salery, M.; Godino, A.; Xu, Y. Q.; Fullard, J. F.; Durand-de Cuttoli, R.; LaBanca, A. R.; Holt, L. M.; Russo, S. J.; Roussos, P.; Nestler, E. J.
10.1101/2023.12.13.571585 — neuroscience — Posted on 2023-12-14
2285 Spatial Transcriptomic Characterization of Novel Pathologic Niches in IPF
Mayr, C. H.; Santacruz, D.; Jarosch, S.; Lempp, C.; Neubert, L.; Rath, B.; Kamp, J. C.; Jonigk, D.; Kuehnel, M.; Schlueter, H.; Doerr, J.; Dick, A.; Ramirez, F.; Thomas, M. J.
10.1101/2023.12.13.571464 — systems biology — Posted on 2023-12-14
2287 Data-driven probabilistic definition of the low energy conformational states of protein residues
Gavalda-Garcia, J.; Bickel, D.; Roca-Martinez, J.; Raimondi, D.; Orlando, G.; Vranken, W. F.
10.1101/2023.07.24.550386 — bioinformatics — Posted on 2023-12-14
2289 Persistence of backtracking by human RNA polymerase II
Yang, K. B.; Rasouly, A.; Epshtein, V.; Martinez, C.; Nguyen, T.; Shamovsky, I.; Nudler, E.
10.1101/2023.12.13.571520 — molecular biology — Posted on 2023-12-14
2293 Most azole antifungal resistance mutations in the drug target provide cross-resistance and carry no intrinsic fitness cost
Bedard, C.; Gagnon-Arsenault, I.; Boisvert, J.; Plante, S.; Dube, A. K.; Pageau, A.; Sharma, J.; Maroc, L.; Shapiro, R. S.; Landry, C. R.
10.1101/2023.12.13.571438 — microbiology — Posted on 2023-12-14
2295 Loss of Endothelial TDP-43 Leads to Blood Brain Barrier Defects in Mouse Models of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Cheemala, A.; Kimble, A. L.; Tyburski, J. D.; Leclair, N.; Zuberi, A.; Murphy, M.; Jellison, E. R.; Reese, B.; Hu, X.; Lutz, C. M.; Yan, R.; Murphy, P. A.
10.1101/2023.12.13.571184 — neuroscience — Posted on 2023-12-14
2296 Targeted inCITE-Seq Analysis Identifies the Loss of Nuclear TDP-43 in Endothelium as a Mediator of Blood Brain Barrier Signaling Pathway Dysfunction in Neurodegeneration
Omar, O. M.; Kimble, A. L.; Cheemala, A.; Tyburski, J. D.; Pandey, S.; Wu, Q.; Reese, B.; Jellison, E. R.; Li, Y.; Hao, B.; Yan, R.; Murphy, P. A.
10.1101/2023.12.13.571178 — neuroscience — Posted on 2023-12-14
2298 A root-specific NLR network confers resistance to plant parasitic nematodes
Luedke, D.; Sakai, T.; Kourelis, J.; Toghani, A.; Adachi, H.; Posbeyikian, A.; Frijters, R.; Pai, H.; Harant, A.; Ernst, K.; Ganal, M.; Verhage, A.; Wu, C.-H.; Kamoun, S.
10.1101/2023.12.14.571630 — plant biology — Posted on 2023-12-14
2300 Melanoma innervation is associated with cancer progression in a zebrafish xenograft model
LORENZINI, F.; MARINES, J.; Le FRIEC, J.; DO KHOA, N.; NIETO, M. A.; SANCHEZ-LAORDEN, B.; MIONE, M.; FONTENILLE, L.; KISSA, K.
10.1101/2023.12.13.571512 — cancer biology — Posted on 2023-12-14
2303 Flow Physics Explains Morphological Diversity of Ciliated Organs
Nawroth, J. C.; Ling, F.; Essock-Burns, T.; Stein, D.; McFall-Ngai, M.; Katija, K.; Shelley, M. J.; Kanso, E.
10.1101/2023.02.12.528181 — biophysics — Posted on 2023-12-14
2307 Allantoic fluid-based qPCR for early-onset in ovo sexing
Santos, S. M. B. d.; Corion, M.; De Ketelaere, B.; Lammertyn, J.; Spasic, D.
10.1101/2023.12.13.571516 — bioengineering — Posted on 2023-12-14
2309 The Horizontal Ladder Test (HLT) protocol: A novel, optimized, and reliable means of assessing motor coordination in Sus scrofa domesticus
Liu, X.; Gutierrez, A. G.; Vega, A.; Willms, J. O.; Driskill, J.; Pathagani, P.; Sanchez, J.; Aguilera, M.; Backus, B.; Bailoo, J. D.; Bergeson, S. E.
10.1101/2023.12.13.571517 — animal behavior and cognition — Posted on 2023-12-14
2316 AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons
Maltby, C. J.; Krans, A.; Grudzien, S. J.; Palacios, Y.; Muinos, J.; Suarez, A.; Asher, M.; Khurana, V.; Barmada, S. J.; Dijkstra, A. A.; Todd, P. K.
10.1101/2023.12.13.571345 — neuroscience — Posted on 2023-12-14
2319 The AMsh glia of C. elegans modulates the duration of touch-induced escape responses
Awe, T.; Aalimah, A.; Niha, S.; Kelly, L.; Adams, J.; Stein, W.; Vidal-Gadea, A. G.
10.1101/2023.12.13.571291 — neuroscience — Posted on 2023-12-14
2321 Feasibility of cognitive neuroscience data collection during a speleological expedition
Paas, A.; Jourde, H. R.; Brignol, A.; Savard, M.-A.; Eyqvelle, Z.; Bassetto, S.; Beltrame, G.; Coffey, E. B. J.
10.1101/2023.12.12.571158 — neuroscience — Posted on 2023-12-14
2322 Stable Cortical Body Maps Before and After Arm Amputation
Schone, H. R.; Maimon-Mor, R. O.; Kollamkulam, M. T.; Gerrand, C.; Woollard, A.; Kang, N. V.; Baker, C. I.; Makin, T. R.
10.1101/2023.12.13.571314 — neuroscience — Posted on 2023-12-14
2325 Phosphorylation Promotes Liquid-Liquid Phase Separation of GRP8 and Its Assembly into Stress Granules Upon Salinity Stress in Arabidopsis
Kasztelan, A.; Maszkowska, J.; Anielska-Mazur, A.; Cieslak, D.; Polkowska-Kowalczyk, L.; Poznanski, J.; Dadlez, M.; Nöh, C.; Steffen, A.; Kasztelan, K.; Bucholc, M.; Szymanska, K. P.; Gutierrez-Beltran, E.; Staiger, D.; Sztatelman, O.; Dobrowolska, G.
10.1101/2023.12.13.571504 — plant biology — Posted on 2023-12-14
2326 CYTOCHROME P450 CYP72A219 IS INVOLVED IN EVOLUTION OF METABOLIC RESISTANCE TO TEMBOTRIONE IN Amaranthus palmeri POPULATIONS
Rigon, C. A. G.; Kupper, A.; Sparks, C.; Montgomery, J.; Peter, F.; Schepp, S.; Perez-Jones, A.; Tranel, P. J.; Beffa, R.; Dayan, F. E.; Gaines, T. A.
10.1101/2023.12.13.571468 — plant biology — Posted on 2023-12-14
2327 New insights on the role of SlDMR6-1 in drought avoidance in tomato
Maioli, A.; De Marchi, F.; Valentino, D.; Gianoglio, S.; Patono, D. L.; Miloro, F.; Bai, Y.; Comino, C.; Lanteri, S.; Lovisolo, C.; Acquadro, A.; Moglia, A.
10.1101/2023.12.14.571645 — plant biology — Posted on 2023-12-14
2328 The prefoldin-like protein AtURI exhibits characteristics of instrinsically disordered proteins.
Gomez-Minguez, Y.; Palacios-Abella, A.; Costigliolo-Rojas, C.; Hernandez-Villa, L.; Barber, M.; Urbez, C.; Alabadi, D.
10.1101/2023.12.13.571423 — plant biology — Posted on 2023-12-14
2333 Battery-Free Optoelectronic Patch for Photodynamic and Light Therapies in Treating Bacteria-Infected Wounds
Xue, Z.; Chou, W.; Xu, Y.; Cheng, Z.; Ren, X.; Sun, T.; Tong, W.; Xie, Y.; Chen, J.; Zhang, N.; Sheng, X.; Wang, Y.; Zhao, H.; Yang, J.; Ding, H.
10.1101/2023.12.13.571417 — bioengineering — Posted on 2023-12-14
2334 Peroxiredoxinylation buffers the redox state of the proteome upon cellular stress
Seisenbacher, G.; Raguz Nakic, Z.; Borras, E.; Sabido, E.; Sauer, U.; de Nadal, E.; Posas, F.
10.1101/2023.12.13.571451 — biochemistry — Posted on 2023-12-14
2335 Membrane-embedded polar residues target membrane proteins for degradation by the quality control protease FtsH
Chai-Danino, M.; Ravensary, N.; Onyshchuk, T.; Plohn, M.; Barshap, A. B. D.; Bsoul, A.; Peled-Zehavi, H.; Fluman, N.
10.1101/2023.12.12.571171 — biochemistry — Posted on 2023-12-14
2338 Response diversity in the context of multifarious environmental change
Polazzo, F.; Limberger, R.; Pennekamp, F.; Ross, S. R. P.-J.; Simpson, G. L.; Petchey, O.
10.1101/2023.12.13.571413 — ecology — Posted on 2023-12-14
2339 Molecular definition of the BAK:VDAC2 interaction as a target to manipulate apoptosis
Yuan, Z.; van Delft, M. F.; Li, M. X.; Sumardy, F.; Smith, B. J.; Huang, D. C. S.; Lessene, G.; Khakham, Y.; Jin, R.; He, S.; Smith, N. A.; Birkinshaw, R.; Czabotar, P. E.; Dewson, G.
10.1101/2023.12.13.571450 — cell biology — Posted on 2023-12-14
2345 Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells
Walsh, Z. H.; Shah, P.; Kothapalli, N.; Nikolenyi, G.; Shah, S.; Leuzzi, G.; Mu, M.; Ho, P.; Abuzaid, S.; Brodtman, Z. D.; Vasan, N.; AlQuaraishi, M. N.; Milner, J. D.; Ciccia, A.; Melms, J. C.; Izar, B.
10.1101/2023.12.13.571465 — immunology — Posted on 2023-12-14
2349 The somato-cognitive action network links diverse neuromodulatory targets for Parkinson's disease
Ren, J.; Zhang, W.; Dahmani, L.; Hu, Q.; Jiang, C.; Bai, Y.; Ji, G.-j.; Zhou, Y.; Zhang, P.; Wang, W.; Wang, K.; Wang, M.; Li, L.; Wang, D.; Liu, H.
10.1101/2023.12.12.571023 — neuroscience — Posted on 2023-12-14
2352 Wind speed affects the rate and kinetics of stomatal conductance
Shapira, O.; Hochberg, U.; McAdam, S.; Azoulay-Shemer, T.; Brodersen, C. R.; Holbrook, N. M.; Zait, Y.
10.1101/2023.12.06.569782 — plant biology — Posted on 2023-12-14
2353 Extensive variation and strain-specificity in dengue virus susceptibility among African Aedes aegypti populations
Dabo, S.; Henrion-Lacritick, A.; Lecuyer, A.; Jiolle, D.; Paupy, C.; Ayala, D.; da Veiga Leal, S.; Badolo, A.; Vega-Rua, A.; Sylla, M.; Akorli, J.; Otoo, S.; Lutomiah, J.; Sang, R.; Mutebi, J.-P.; Saleh, M.-C.; Rose, N.; McBride, C.; Lambrechts, L.
10.1101/2023.12.14.571617 — microbiology — Posted on 2023-12-14
2357 Characterization of bovine vaginal microbiota and its relationship with host fertility, health, and production
Brulin, L.; Ducrocq, S.; Even, G.; Sanchez, M.-P.; Martel, S.; Merlin, S.; Audebert, C.; Croiseau, P.; Estelle, J.
10.1101/2023.12.13.571514 — microbiology — Posted on 2023-12-14
2358 Pigs are highly susceptible to but do not transmit mink-derived highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b
Kwon, T.; Trujillo, J. D.; Carossino, M.; Lyoo, E. L.; McDowell, C. D.; Cool, K.; Matias-Ferreyra, F. S.; Jeevan, T.; Morozov, I.; Gaudreault, N. N.; Balasuriya, U.; Webby, R. J.; Osterrieder, N.; Richt, J. A.
10.1101/2023.12.13.571575 — microbiology — Posted on 2023-12-14
2361 A broad antibody class engages the influenza virus hemagglutinin head at its stem interface
Simmons, H. C.; Finney, J.; Kotaki, R.; Adachi, Y.; Moseman, A. P.; Watanabe, A.; Song, S.; Robinson-McCarthy, L. R.; Le Sage, V.; Kuraoka, M.; Moseman, E. A.; Kelsoe, G.; Takahashi, Y.; McCarthy, K. R.
10.1101/2023.12.13.571543 — microbiology — Posted on 2023-12-14
2362 Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity
Fernandez-Ciruelos, B. M.; Albanese, M.; Adhav, A.; Solomin, V.; Ritchie-Martinez, A.; Taverne, F.; Velikova, N.; Jirgensons, A.; Marina, A.; Finn, P. W.; Wells, J. M.
10.1101/2023.12.13.571547 — microbiology — Posted on 2023-12-14
2364 Divergence in herbivore resistance during the invasion of a global plant invader
Cao, P.; Wang, S.; Zhang, L.; Parepa, M.; Lin, T.; Bi, J.; Zhao, Y.; Endriss, S. B.; Guo, Y.; Bossdorf, O.; Richards, C. L.; Wu, J.; Ju, R.; Liao, Z.; Li, B.
10.1101/2023.12.13.571471 — ecology — Posted on 2023-12-14
2365 Neoadjuvant Therapy Differentially Remodels Carcinoma and the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma: Insights from Spatial Transcriptomics and Single-nucleus RNA Sequencing
Zhang, X.; Liu, Y.-Z.; Lan, R.; Liu, Y.; Pillarisetty, V. G.; Li, D.; Zhao, C. L.; Sarkar, S.; Liu, W.; Hanna, I.; Gupta, M.; Hajdu, C.; Melamed, J.; Widmer, J.; Allendorf, J.
10.1101/2023.10.26.564099 — cancer biology — Posted on 2023-12-14
2366 PhysiCell Studio: a graphical tool to make agent-based modeling more accessible
Heiland, R.; Bergman, D. R.; Lyons, B.; Cass, J.; L. Rocha, H.; Ruscone, M.; Noël, V.; Macklin, P.
10.1101/2023.10.24.563727 — bioinformatics — Posted on 2023-12-14
2368 Extracellular Matrix Protein 1 Attenuates Hepatic Fibrosis by Inhibiting TSP-, ADAMTS-, and MMP-Mediated Latent TGF-β1 Activation
Link, F.; Li, Y.; Zhao, J.; Munker, S.; Fan, W.; Nwosu, Z.; Yao, Y.; Hammad, S.; Liebe, R.; Liu, H.; Shao, C.; Sun, B.; Torok, N. J.; Ding, H.; Ebert, M.; Weng, H.; Dijke, P. t.; Drasdo, D.; Dooley, S.; Wang, S.
10.1101/2023.12.12.571289 — cell biology — Posted on 2023-12-14
2372 The how, when, and what of odor valence communication between the olfactory bulb and piriform cortex
Norden, F.; Iravani, B.; Schaefer, M.; Winter, A. L.; Lundqvist, M.; Arshamian, A.; Lundström, J. N.
10.1101/2023.11.02.564696 — neuroscience — Posted on 2023-12-14
2373 Arabidopsis actin-binding protein WLIM2A links PAMP-triggered immunity and cytoskeletal organization
Manickam, P.; Abulfaraj, A. A.; Alhoraibi, H. M.; Veluchamy, A.; Almeida-Trapp, M.; Hirt, H.; Rayapuram, N.
10.1101/2023.12.13.571563 — plant biology — Posted on 2023-12-14
2374 In silico mechanics and TGF-β expression of stem cells intramyocardially transplanted with a biomaterial injectate for treatment of myocardial infarction
Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Nchejane, N. J.; Abdalrahman, T.; Nagawa, J.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.
10.1101/2023.05.10.540185 — bioengineering — Posted on 2023-12-14
2375 Bespoke single cell molecular and tissue-scale analysis reveals mechanisms underpinning development and disease in complex developing cell populations
Strauss, M. E.; Ton, M.-L. N.; Mason, S.; Bagri, J.; Harland, L. T.; Imaz-Rosshandler, I.; Wilson, N.; Nichols, J.; Tyser, R. C.; Gottgens, B.; Marioni, J. C.; Guibentif, C.
10.1101/2023.10.11.561904 — genomics — Posted on 2023-12-14
2376 Technical and biological sources of unreliability of Infinium probes on Illumina Methylation microarrays
Nazarenko, T.; Vavourakis, C. D.; Jones, A.; Evans, I.; Watson, A.; Brandt, K.; Carter, C.; Zaikin, A.; Herzog, C.; Widschwendter, M.
10.1101/2023.03.14.532595 — genomics — Posted on 2023-12-14
2377 Tracking subjects' strategies in behavioural choice experiments at trial resolution
Maggi, S.; Hock, R. M.; O'Neill, M.; Buckley, M. J.; Moran, P. M.; Bast, T.; Sami, M.; Humphries, M. D.
10.1101/2022.08.30.505807 — neuroscience — Posted on 2023-12-14
2379 Human Heart Failure Alters Mitochondria and Fiber 3D Structure Triggering Metabolic Shifts
Vue, Z.; Ajayi, P. T.; Neikirk, K.; Murphy, A.; Prasad, P.; Jenkins, B. C.; Vang, L.; Garza-Lopez, E.; Mungai, M.; Marshall, A. G.; Beasley, H. K.; Killion, M.; Parker, R.; Anukodem, J.; Lavine, K.; Ajijola, O.; Mobley, B.; Dai, D.-F.; Exil, V.; Kirabo, A.; Ru Su, Y.; Tomasek, K.; Zhang, X.; Wanjalla, C. N.; Hubert, D. L.; Shao, J.; Phillips, M. A.; McReynolds, M.; Glancy, B.; Hinton, A.
10.1101/2023.11.28.569095 — physiology — Posted on 2023-12-14
2380 3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes
Scudese, E.; Vue, Z.; Katti, P.; Marshall, A.; Vang, L.; Garza Lopez, E.; Neikirk, K.; Stephens, D.; Hall, D. D.; Rostami, R.; Shao, J.-q.; Mungai, M.; AshShareef, S.; Hicsasmaz, I.; Manus, S.; Whiteside, A.; Williams, C.; Damo, S.; Gaddy, J.; Kirabo, A.; Glancy, B.; Henrique Martin Dantas, E.; Kinder, A.; Scartoni, F.; Baffi, M.; McReynolds, M.; Wanjalla, C. N.; Phillips, M. A.; Exil, V.; Mobley, B.; Hinton, A.
10.1101/2023.11.13.566502 — biophysics — Posted on 2023-12-14
2382 Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
Zambo, B.; Edelweiss, E.; Morlet, B.; Negroni, L.; Pajkos, M.; Dosztanyi, Z.; Ostergaard, S.; Trave, G.; Laporte, J.; Gogl, G.
10.1101/2023.02.14.528471 — biochemistry — Posted on 2023-12-14
2384 A barley MLA receptor is targeted by a non-ribosomal peptide effector of the necrotrophic spot blotch fungus for disease susceptibility
Leng, Y.; Kümmel, F.; Zhao, M.; Molnar, I.; Dolezel, J.; Logemann, E.; Köchner, P.; Xi, P.; Yang, S.; Moscou, M. J.; Fiedler, J. D.; Du, Y.; Steuernagel, B.; Meinhardt, S.; Steffenson, B. J.; Schulze-Lefert, P.; Zhong, S.
10.1101/2023.12.13.571418 — plant biology — Posted on 2023-12-14
2385 The leucine-rich repeat receptor kinase QSK1 is a novel regulator of PRR-RBOHD complex and is employed by the bacterial effector HopF2Pto to modulate plant immunity
Goto, Y.; Kadota, Y.; Mbengue, M.; Lewis, J. D.; Matsui, H.; Maki, N.; Sklenar, J.; Derbyshire, P.; Shibata, A.; Ichihashi, Y.; Guttman, D.; Nakagami, H.; Suzuki, T.; Menke, F. L. H.; Robatzek, S.; Desveaux, D.; Zipfel, C.; Shirasu, K.
10.1101/2023.12.13.571443 — plant biology — Posted on 2023-12-14
2386 Near chromosome-level and highly repetitive genome assembly of the snake pipefish Entelurus aequoreus (Syngnathiformes: Syngnathidae)
Wolf, M.; Ferrette, B. L. S.; Coimbra, R. T. F.; de Jong, M.; Nebenfuehr, M.; Prochotta, D.; Schoeneberg, Y.; Zapf, K.; Rosenbaum, J.; Mc Intyre, H. A.; Maier, J.; de Souza, C. C. S.; Gehlhaar, L. M.; Werner, M. J.; Oechler, H.; Wittekind, M.; Sonnewald, M.; Nilsson, M. A.; Janke, A.; Winter, S.
10.1101/2023.12.12.571260 — genomics — Posted on 2023-12-13
2388 De novo genome assembly of four Andean potato weevil species (Premnotrypes,Rhigopsidius), the primary agricultural pest of the potato in South America
Jorgensen, K.; Garcia, O. A.; Alcazar, J.; Walden, K. K. O.; Bigham, A. W.; Moron, N. M.; Cobian, C. V.; Lesnik, J. J.; Fan, C.
10.1101/2023.12.13.571405 — genomics — Posted on 2023-12-13
2390 Yeast EndoG prevents genome instability by degrading cytoplasmic DNA
Ira, G.; Yu, Y.; Wang, X.; Chen, K.; Fox, J.; Hastings, P. J.; Dang, W.; Thakre, P.; McCauley, B.; Nikoloutsos, N.; Li, Q.
10.1101/2023.12.13.571550 — genetics — Posted on 2023-12-13
2396 Collaborative metabolic curation of an emerging model marine bacterium, Alteromonas macleodii ATCC 27126
Sher, D.; George, E. E.; Wietz, M.; Gifford, S. M.; Zoccaratto, L.; Weissberg, O.; Koedooder, C.; VK, W. B.; Malisano Barreto Filho, M.; Mireles, R.; Malavin, S.; Liddor-Naim, M.; Idan, T.; Shrivastava, V.; Itelson, L.; Sade, D.; Abu Hamoud, A.; Soussan, Y.; Barak, N.; Karp, P. D.; Moore, L. D.
10.1101/2023.12.13.571488 — microbiology — Posted on 2023-12-13
2400 Syncytia Formation Promotes Virus Resistance to Interferon and Neutralizing Antibodies
Li, T.; Kang, I.; Hu, Z.; Gibbs, J.; Ye, C.; Kosik, I.; Shi, G.; Holly, J.; Kosikova, M.; Compton, A. A.; Martinez-Sobrido, L.; Johnson, R.; Hang, X.; Yewdell, J. W.
10.1101/2023.12.12.571262 — microbiology — Posted on 2023-12-13
2401 Human Trophoblast Stem Cells Restrict Human Cytomegalovirus Replication
Rollman, T. B.; Berkebile, Z. W.; Okae, H.; Bardwell, V. J.; Gearhart, M. D.; Bierle, C. J.
10.1101/2023.12.13.571456 — microbiology — Posted on 2023-12-13
2405 An explainable machine learning data analytics method using TIGIT-linked genes for identifying biomarker signatures to clinical outcomes.
G, S.; Agrawal, D.; Bhat, S.; Mandal, T.; Kashipathi, S.; Madhusudhan, M. S.; Rodrigues, G.; Ghosh, M.; Chirmule, N.
10.1101/2023.12.05.570321 — cancer biology — Posted on 2023-12-13
2410 Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability
Bashour, H.; Smorodina, E.; Pariset, M.; Zhong, J.; Akbar, R.; Chernigovskaya, M.; Le Quy, K.; Snapkov, I.; Rawat, P.; Krawczyk, K.; Sandve, G. K.; Gutierrez-Marcos, J.; Nakhaee-Zadeh Gutierrez, D.; Andersen, J. T.; Greiff, V.
10.1101/2023.10.26.563958 — bioinformatics — Posted on 2023-12-13
2411 A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines
Lee, J.; Stewart, C.; Schaefer, A.; Leaf, E. M.; Park, Y.-J.; Asarnow, D.; Powers, J. M.; Treichel, C.; Corti, D.; Baric, R.; King, N. P.; Veesler, D.
10.1101/2023.12.12.571160 — biochemistry — Posted on 2023-12-13
2412 DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks
Göder, A.; Maric, C.; Rainey, M. D.; Cazzaniga, C.; Shamavu, D.; Cadoret, J.-C.; Santocanale, C.
10.1101/2023.12.13.568031 — biochemistry — Posted on 2023-12-13
2417 Lysine-36 of Drosophila histone H3.3 supports adult longevity
Brown, J. C.; McMichael, B. D.; Vandadi, V.; Mukherjee, A.; Salzler, H. R.; Matera, A. G.
10.1101/2023.09.28.559962 — genetics — Posted on 2023-12-13
2418 ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin
Cacho-Navas, C.; Lopez-Pujante, C.; Reglero-Real, N.; Colas-Algora, N.; Cuervo, A.; Conesa, J. J.; Barroso, S.; Ciordia, S.; Paradela, A.; D'Agostino, G.; Manzo, C.; Feito, J.; Andres, G.; Molina-Jimenez, F.; Majano, P.; Correas, I.; Carazo, J. M.; Nourshargh, S.; Huch, M.; Millan, J.
10.1101/2023.07.18.549509 — cell biology — Posted on 2023-12-13
2422 Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity
Appios, A.; Davies, J.; Sirvent, S.; Henderson, S.; Trzebanski, S.; Schroth, J.; Law, M. L.; Boal Carvalho, I.; Yuan-Hao Kan, H.; Lovlekar, S.; Major, C.; Vallejo, A.; Hall, N. J.; Ardern-Jones, M.; Henson, S. M.; Emmerson, E.; Jung, S.; Polak, M. E.; Bennett, C. L.
10.1101/2023.11.13.566862 — immunology — Posted on 2023-12-13
2428 Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer's disease and aging
Paudel, B.; Jeong, S.-Y.; Martinez, C. P.; Rickman, A.; Haluck-Kangas, A.; Bartom, E. T.; Frederiksen, K.; Affaneh, A.; Kessler, J. A.; Mazzulli, J. R.; Murmann, A. E.; Rogalski, E.; Geula, C.; Ferreira, A.; Heckmann, B. L.; Green, D. R.; Sadleir, K. R.; Vassar, R.; Peter, M. E.
10.1101/2022.09.08.507157 — neuroscience — Posted on 2023-12-13
2432 Nuclear GSH import precedes coordinated cell cycle changes during regeneration
Lee, L. R.; Guillotin, B.; Hutchison, C.; Desvoyes, B.; Gutierrez, C.; Birnbaum, K. D.
10.1101/2023.11.28.569014 — plant biology — Posted on 2023-12-13
2433 Competitive Amplification Networks enable molecular pattern recognition with PCR
Goertz, J. P.; Sedgwick, R.; Smith, F.; Kaforou, M. P.; Wright, V. J.; Herberg, J. A.; Kote-Jarai, Z.; Eeles, R.; Levin, M.; Misener, R.; van der Wilk, M.; Stevens, M. M.
10.1101/2023.06.29.546934 — bioengineering — Posted on 2023-12-13
2434 ESM-Scan - a tool to guide amino acid substitutions
Totaro, M.; Vide, U.; Zausinger, R.; Winkler, A.; Oberdorfer, G.
10.1101/2023.12.12.571273 — biochemistry — Posted on 2023-12-13
2435 Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Cozzolino, K.; Sanford, L.; Hunter, S.; Molison, K.; Erickson, B.; Jones, T.; Ajit, D.; Galbraith, M. D.; Espinosa, J. M.; Bentley, D. L.; Allen, M. A.; Dowell, R. D. A.; Taatjes, D. J.
10.1101/2023.07.05.547813 — biochemistry — Posted on 2023-12-13
2436 Population Genomics of Postglacial Western Eurasia
Allentoft, M. E.; Sikora, M.; Refoyo-Martinez, A.; Irving-Pease, E. K.; Fischer, A.; Barrie, W.; Ingason, A.; Stenderup, J.; Sjögren, K.-G.; Pearson, A.; Sousa da Mota, B.; Paulsson, B. S.; Halgren, A. S.; Macleod, R.; Schjellerup Jorkov, M. L.; Demeter, F.; Novosolov, M.; Sorensen, L.; Nielsen, P. O.; Henriksen, R. A.; Vimala, T.; McColl, H.; Margaryan, A.; Ilardo, M.; Vaughn, A.; Mortensen, M. F.; Nielsen, A. B.; Hede, M. U.; Rasmussen, P.; Vinner, L.; Renaud, G.; Stern, A. J.; Trolle Jensen, T. Z.; Johannsen, N. N.; Scorrano, G.; Schroeder, H.; Lysdahl, P.; Ramsoe, A.; Skorobogatov, A.; Sc
10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2023-12-13
2438 A Novel Imaging Method (FIM-ID) Reveals that Myofibrillogenesis Plays a Major Role in the Mechanically Induced Growth of Skeletal Muscle
Jorgenson, K. W.; Hibbert, J. E.; Sayed, R. K.; Lange, A. N.; Godwin, J. S.; Mesquita, P. H.; Ruple, B. A.; McIntosh, M. C.; Kavazis, A. N.; Roberts, M. D.; Hornberger, T. A.
10.1101/2023.09.13.557204 — cell biology — Posted on 2023-12-13
2439 Microbially-catalyzed conjugation of GABA and tyramine to bile acids
Mullowney, M.; Fiebig, A.; Schnizlein, M.; McMillin, M.; Rose, A. R.; Koval, J.; Rubin, D.; Dalal, S.; Sogin, M.; Chang, E.; Sidebottom, A.; Crosson, S.
10.1101/2023.09.25.559407 — microbiology — Posted on 2023-12-13
2441 Morphology and ultrastructure of external sense organsof Drosophila larvae
Richter, V.; Rist, A.; Kislinger, G.; Laumann, M.; Schoofs, A.; Miroschnikow, A.; Pankratz, M.; Cardona, A.; Thum, A. S.
10.1101/2023.08.23.554405 — neuroscience — Posted on 2023-12-13
2442 Foveal drusen increase fixation instability: fixational eye movements as biomarkers for pre-symptomatic AMD
Murari, J.; Gautier, J.; Daout, J.; Krafft, L.; Senee, P.; Mece, P.; Seiple, W.; Grieve, K.; Sheynikhovich, D.; Meimon, S.; Paques, M.; Arleo, A.
10.1101/2023.10.09.560481 — neuroscience — Posted on 2023-12-13
2443 Organelle phenotyping and multi-dimensional microscopy identify C1q as a novel regulator of microglial function.
Sakthivel, P. S.; Scipioni, L.; Karam, J.; Keulen, Z.; Blurton-Jones, M.; Gratton, E.; Anderson, A.
10.1101/2023.12.12.571151 — neuroscience — Posted on 2023-12-13
2446 Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
Tomlinson, P. R.; Knox, R.; Perisic, O.; Su, H.; Brierley, G. V.; Williams, R. L.; Semple, R. K.
10.1101/2023.11.02.565250 — biochemistry — Posted on 2023-12-13
2449 Characterization of carotenoid-producing Muricauda sp. strains isolated from the reef-building coral Galaxea fascicularis and subtropical seawater
Endo, F.; Motone, K.; Kai, K.; Kitakaze, T.; Nishikawa, Y.; Nishimura, Y.; Kitamura, R.; Takagi, T.; Ito, M.; Miura, N.; Kataoka, M.
10.1101/2023.12.12.571358 — microbiology — Posted on 2023-12-13
2453 Keratinocyte Piezo1 drives paclitaxel-induced mechanical hypersensitivity
Mikesell, A. R.; Isaeva, E.; Schulte, M. L.; Menzel, A. D.; Sriram, A.; Prahl, M. M.; Shin, S. M.; Sadler, K. E.; Yu, H. E.; Stucky, C. L.
10.1101/2023.12.12.571332 — neuroscience — Posted on 2023-12-13
2454 Evaluation of resampling-based inference for topological features of neuroimages
Vandekar, S. N.; Kang, K.; Woodward, N. D.; Huang, A.; McHugo, M.; Garbeet, S.; Stephens, J.; Shinohara, R.; Schwartzman, A.; Blume, J.
10.1101/2023.12.12.571377 — neuroscience — Posted on 2023-12-13
2455 Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.
Conn, K.; Milton, L. K.; Huang, K.; Munguba, H.; Ruuska, J.; Lemus, M. B.; Greaves, E.; Homman-Ludiye, J.; Oldfield, B. J.; Foldi, C. J.
10.1101/2023.12.12.571374 — neuroscience — Posted on 2023-12-13
2462 Location analysis of presynaptically active and silent synapses in single-cultured hippocampal neurons
Kitaoka, O.; Oyabu, K.; Kubota, K.; Watanabe, T.; Kondo, S.; Matsui, T.; Katsurabayashi, S.; Iwasaki, K.
10.1101/2023.12.12.571354 — neuroscience — Posted on 2023-12-13
2463 Detecting Features of Protein Structure through their Mediator-Accessible Redox Activities
Motabar, D.; Kim, E.; Li, J.; Zhao, Z.; Mouchahoir, T.; Gallagher, D. T.; Schiel, J. E.; Garige, M.; Sourbier, C.; Payne, G. F.; Bentley, W. E.
10.1101/2023.12.12.571363 — bioengineering — Posted on 2023-12-13
2464 Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma
Flesken-Nikitin, A.; Ralston, C. Q.; Fu, D.-J.; De Micheli, A. J.; Phuong, D. J.; Harlan, B. A.; Armstrong, A. P.; McKellar, D.; Ghuwalewala, S.; Schimenti, J. C.; Cosgrove, B. D.; Nikitin, A. Y.
10.1101/2023.12.12.571315 — cancer biology — Posted on 2023-12-13
2466 Seasonal and environmental factors contribute to the variation in the gut microbiome: a large-scale study of a small bird
Liukkonen, M.; Muriel, J.; Martinez-Padilla, J.; Nord, A.; Pakanen, V.-M.; Rosivall, B.; Tilgar, V.; van Oers, K.; Grond, K.; Ruuskanen, S.
10.1101/2023.12.12.571395 — ecology — Posted on 2023-12-13
2469 Hybracter: Enabling Scalable, Automated, Complete and Accurate Bacterial Genome Assemblies
Bouras, G.; Houtak, G.; Wick, R. R.; Mallawaarachchi, V.; Roach, M. J.; Papudeshi, B.; Judd, L. M.; Sheppard, A. E.; Edwards, R. A.; Vreugde, S.
10.1101/2023.12.12.571215 — bioinformatics — Posted on 2023-12-13
2470 Shared features underlying compact genomes and extreme habitat use in chironomid midges
Nell, L. A.; Weng, Y.-M.; Phillips, J. S.; Botsch, J. C.; Book, K. R.; Einarsson, A.; Ives, A. R.; Schoville, S. D.
10.1101/2023.12.12.571347 — genomics — Posted on 2023-12-13
2473 AlphaFold2 has more to learn about protein energy landscapes
Chakravarty, D.; Schafer, J. W.; Chen, E. A.; Thole, J.; Porter, L.
10.1101/2023.12.12.571380 — bioinformatics — Posted on 2023-12-13
2475 Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation
Vincow, E. S.; Thomas, R. E.; Milstein, G.; Pareek, G.; Bammler, T. K.; MacDonald, J.; Pallanck, L. J.
10.1101/2023.12.13.571406 — genetics — Posted on 2023-12-13
2477 Loss-of-function mutation in the polyamine transporter gene OsLAT5 as a selectable marker for genome editing
Schenstnyi, K.; Zhang, Z.; Liu, B.; Nakamura, M.; Schepler-Luu, V.; Loo, E. P.; Yang, B.; Frommer, W. B.
10.1101/2023.12.12.571390 — plant biology — Posted on 2023-12-13
2479 ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics
Li, Z. L.; Weller, C.; Shah, S.; Johnson, N.; Hao, Y.; Roberts, J.; Bereda, C.; Klaisner, S.; Machado, P.; Fratta, P.; Petrucelli, L.; Prudencio, M.; Oskarsson, B.; Staff, N.; Dickson, D.; Cookson, M.; Ward, M.; Singleton, A.; Nalls, M.; Qi, Y.
10.1101/2023.12.12.571327 — bioinformatics — Posted on 2023-12-13
2481 Gene loss and relaxed selection of plaat1 in vertebrates adapted to low-light environments
Drabeck, D.; Wiese, J.; Gilbertson, E.; Arroyave, J.; Arcila, D.; Alter, S. E.; Borowsky, R.; Hendrickson, D.; Stiassny, M. L.; McGaugh, S. E.
10.1101/2023.12.12.571336 — evolutionary biology — Posted on 2023-12-13
2483 Human neuron subtype programming through combinatorial patterning with scSeq readouts
Lin, H.-C.; Janssens, J.; Kroell, A.-S.; Hornauer, P.; Santel, M.; Okamoto, R.; Karava, K.; Priouret, M.; Garcia, M. P.; Schroeter, M.; Camp, G.; Treutlein, B.
10.1101/2023.12.12.571318 — bioengineering — Posted on 2023-12-13
2486 Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome
Baba, S.; Shinjo, S.; Seya, D.; Bochimoto, H.; Akaike, T.; Nakano, A.; Minamisawa, S.
10.1101/2023.12.12.571383 — developmental biology — Posted on 2023-12-13
2491 Development of endothelial-targeted CD39 as a therapy for ischaemic stroke
Lee, N. T.; Savvidou, I.; Selan, C.; Calvello, I.; Wright, D. K.; Brkljaca, R.; Willcox, A.; Chia, J. S.-J.; Wang, X.; Peter, K.; Robson, S.; Medcalf, R. L.; Nandurkar, H. H.; Sashindranath, M.
10.1101/2023.12.12.571382 — neuroscience — Posted on 2023-12-13
2493 Contrasting levels of transcriptome-wide SNP diversity and decoupled patterns of molecular and functional adaptive variation in conifers
Pavy, N.; gerardi, s.; Prunier, J.; Rigault, P.; Laroche, J.; Daigle, G.; Boyle, B.; MacKay, J. J.; Bousquet, J.
10.1101/2023.12.12.571309 — plant biology — Posted on 2023-12-13
2494 Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis
Li, Z. P.; Moreau, H.; Petit, J. D.; Souza-Moraes, T.; Smokvarska, M.; Perez-Sancho, J.; Petrel, M.; Decoeur, F.; Brocard, L.; Chambaud, C.; Grison, M.; Paterlini, A.; Hoornaert, L.; Joshi, A. S.; Gontier, E.; Prinz, W. A.; Jaillais, Y.; Taly, A.; Campelo, F.; Caillaud, M.-c.; Bayer, E. M.
10.1101/2023.12.12.571296 — plant biology — Posted on 2023-12-13
2495 MBD2 couples DNA methylation to Transposable Elements silencing during male gametogenesis.
Wang, S.; Wang, M.; Ichino, L.; Boone, B. A.; Zhong, Z.; Papareddy, R. K.; Lin, E. K.; Yun, J.; Feng, S.; Jacobsen, S. E.
10.1101/2023.12.12.571353 — plant biology — Posted on 2023-12-13
2496 Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change
Dehkordi, S. R.; Wong, I. T.-L.; Ni, J.; Luebeck, J.; Zhu, K.; Prasad, G.; Krockenberger, L.; Xu, G.; Chowdhury, B.; Rajkumar, U.; Caplin, A.; Muliaditan, D.; Coruh, C.; Jin, Q.; Turner, K.; Teo, S. X.; Pang, A. W. C.; Alexandrov, L.; Chua, C. E. L.; Furnari, F.; Paulson, T.; Law, J.; Chang, H.; Yue, F.; DasGupta, R.; Zhao, J.; Mischel, P. S.; Bafna, V.
10.1101/2023.12.12.571349 — cancer biology — Posted on 2023-12-13
2498 Identification of an allele-specific transcription factor binding interaction that regulates PLA2G2A gene expression
Hara, A.; Lu, E.; Johnstone, L.; Wei, M.; Sun, S.; Hallmark, B.; Watkins, J. C.; Zhang, H. H.; Yao, G.; Chilton, F. H.
10.1101/2023.12.12.571290 — bioinformatics — Posted on 2023-12-13
2501 Connectivity of marine predators over the Patagonian Shelf during the highly pathogenic avian influenza (HPAI) outbreak
Riaz, J.; Orben, R. A.; Gamble, A.; Tierney, M.; Catry, P.; Campioni, L.; Granadeiro, J. P.; Baylis, A. M. M.
10.1101/2023.12.12.570574 — ecology — Posted on 2023-12-13
2503 Staphylococcus aureus can use an alternative pathway to be internalized by osteoblasts in absence of β1 integrins
Mouton, W.; Tricou, L.-P.; Cara, A.; Trouillet-Assant, S.; Bouvard, D.; Laurent, F.; Diot, A.; Josse, J.
10.1101/2023.12.13.571096 — cell biology — Posted on 2023-12-13
2504 Securin Regulates the Spatiotemporal Dynamics of Separase
Turpin, C. G. S.; Sloan, D.; LaForest, M.; Klebanow, L. U.; Mitchell, D.; Severson, A. F.; Bembenek, J. N.
10.1101/2023.12.12.571338 — cell biology — Posted on 2023-12-13
2505 Mechanical transapical coupling of endometrial epithelial cells during implantation
Sakurai, J.; Kinoshita, N.; Otani, T.; Koyama, H.; Furuse, M.; Fujimori, T.
10.1101/2023.12.12.571398 — cell biology — Posted on 2023-12-13
2507 Proximity labeling reveals dynamic changes in the SQSTM1 protein network
Ortiz, A. N. R.; Zhang, L.; Ash, P. E. A.; Basu, A.; Puri, S.; Van der Spek, S.; Dorrian, L.; Emili, A.; Wolozin, B.
10.1101/2023.12.12.571324 — cell biology — Posted on 2023-12-13
2508 Exploring the prokaryote-eukaryote interplay in microbial mats from an Andean athalassohaline wetland
Lopez-Garcia, P.; Cubillos, C. F.; Aguilar, P.; Moreira, D.; Bertolino, P.; Iniesto, M.; Dorador, C.
10.1101/2023.12.05.570274 — microbiology — Posted on 2023-12-13
2509 Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain
Bonnifet, T.; Sinnassamy, S.; Beaudoin, O.; Mailly, P.; Monnet, H.; Loew, D.; Lombard, B.; Servant, N.; Joshi, R.; Fuchs, J.
10.1101/2023.12.12.571308 — neuroscience — Posted on 2023-12-13
2514 Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques
Lee, B.-C.; Gin, A.; Wu, C.; Singh, K.; Grice, M.; Mortlock, R.; Abraham, D.; Fan, X.; Zhou, Y.; AlJanahi, A.; Choi, U.; de Ravin, S. S.; Shin, T.; Hong, S.; Dunbar, C.
10.1101/2023.12.13.571396 — cell biology — Posted on 2023-12-13
2516 Rapid, concerted switching of the neural code in inferotemporal cortex
Shi, Y.; Bi, D.; Hesse, J. K.; Lanfranchi, F. F.; Chen, S.; Tsao, D. Y.
10.1101/2023.12.06.570341 — neuroscience — Posted on 2023-12-13
2517 Brain encoding of naturalistic, continuous, and unpredictable tactile events
Castellani, N.; Federici, A.; Fantoni, M.; Ricciardi, E.; Garbarini, F.; Bottari, D.
10.1101/2023.12.08.570756 — neuroscience — Posted on 2023-12-13
2518 Why can we detect lianas from space?
Visser, M. D.; Detto, M.; Meunier, F.; Wu, J.; Bongalov, B.; Coomes, D.; Nunes, M. H.; Guzman Q., J. A.; Sanchez-Azofeifa, A.; Foster, J.; Broadbent, E.; Verbeeck, H.; Marvin, D.; Chandler, C. J.; van der Heijden, G. M. F.; Boyd, D. S.; Foody, G. M.; Cutler, M. E. J.; Serbin, S.; Schnitzer, S. A.; Rodriguez-Ronderos, M. E.; Pacala, S. W.
10.1101/2021.09.30.462145 — plant biology — Posted on 2023-12-13
2520 Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis
Pacyna, C. N.; Anandapadamanaban, M.; Loudon, K. W.; Hay, I. M.; Perisic, O.; Li, R.; Byrne, M.; Allen, L.; Roberts, K.; Hooks, Y.; Warren, A. Y.; Stewart, G. D.; Clatworthy, M. R.; Teichmann, S.; Behjati, S.; Campbell, P. J.; Williams, R. L.; Mitchell, T. J.
10.1101/2023.12.12.570785 — cancer biology — Posted on 2023-12-13
2523 INTEGRATED GLOBAL CHICKEN REFERENCE PANEL FROM 13,187 CHICKEN GENOMES
Zhu, D.; Wang, Y.; Qu, H.; Feng, C.; Zhang, H.; Sheng, Z.; Jiang, Y.; Nie, Q.; Chu, S.; Shu, D.; Zhang, D.; Fang, L.; Zhao, Y.; Wang, Y.; Hu, X.
10.1101/2023.12.12.571301 — bioinformatics — Posted on 2023-12-13
2524 EasyCircR:Detection and reconstruction of circular RNAs post-transcriptional regulatory interaction networks
Aparo, A.; Avesani, S.; Parmigiani, L.; Napoli, S.; Bertoni, F.; Bonnici, V.; Cascione, L.; Giugno, R.
10.1101/2023.12.12.571275 — bioinformatics — Posted on 2023-12-13
2525 Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging.
Pulfer, A.; Pizzagalli, D. U.; Gagliardi, P. A.; Hinderling, L.; Lopez, P.; Zayats, R.; Barbera, P. C.; Antonello, P.; Segura, M. P.; Graedel, B.; Nicolai, M.; Giusti, A.; Thelen, M.; Gambardella, L. M.; Murooka, T.; Pertz, O.; Krause, R.; Gonzalez, S. F.
10.1101/2022.11.23.517318 — bioinformatics — Posted on 2023-12-13
2526 WITHDRAWN: Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells
Lazzerini Ospri, L.; Zhan, J. J.; Thomsen, M.; Wang, H.; Messanvi, F.; du Hoffmann, J.; Cravedi, K.; Chudasama, Y.; Zhao, H.; Hattar, S.; Komal, R.
10.1101/2023.09.22.556752 — neuroscience — Posted on 2023-12-13
2527 Advancing Virus-Induced Gene Silencing in Sunflower: key factors of VIGS spreading and a novel simple protocol
Mardini, M.; Kazancev, M.; Ivoilova, E.; Utkina, V.; Vlasova, A.; Demurin, Y.; Soloviev, A.; Kirov, I.
10.1101/2023.12.12.571232 — plant biology — Posted on 2023-12-13
2529 Hop stunt viroid infection alters host heterochromatin
Marquez-Molins, J.; Cheng, J.; Corell-Sierra, J.; Juarez-Gonzalez, V. T.; Villalba-Bermell, P.; Annacondia, M. L.; Gomez, G.; Martinez, G.
10.1101/2023.12.12.571286 — plant biology — Posted on 2023-12-13
2531 The association of longitudinal diet and waist-to-hip ratio from midlife to old age with hippocampus connectivity and memory in old age: a cohort study
Jensen, D. E.; Ebmeier, K. P.; Akbaraly, T.; Jansen, M. G.; Singh-Manoux, A.; Kivimäki, M.; Zsoldos, E.; Klein-Flügge, M. C.; Suri, S.
10.1101/2023.12.12.570778 — neuroscience — Posted on 2023-12-13
2532 Functional divergence shaped the network architecture of plant immune receptors
Huang, C.-Y.; Huang, Y.-S.; Sugihara, Y.; Wang, H.-Y.; Huang, L.-T.; Lopez-Agudelo, J. C.; Chen, Y.-F.; Lin, K.-Y.; Chiang, B.-J.; Toghani, A.; Kourelis, J.; Derevnina, L.; Wu, C.-H.
10.1101/2023.12.12.571219 — plant biology — Posted on 2023-12-13
2538 Nucleic Quasi-Primes: Identification of the Shortest Unique Oligonucleotide Sequences in a Species
Mouratidis, I.; Konnaris, M. A.; Chantzi, N.; Chan, C. S. Y.; Montgomery, A.; Baltoumas, F. A.; Patsakis, M.; Mareboina, M.; Pavlopoulos, G.; Chartoumpekis, D. V.; Georgakopoulos-Soares, I.
10.1101/2023.12.12.571240 — genomics — Posted on 2023-12-13
2539 Single cell sequencing as a general variant interpretation assay
Xu, H.; Chen, L.; Sun, M.; Jean-Baptiste, K.; Cao, D.; Zhou, X.; Wong, S.; Xiao, C.; Liu, T.; Quijano, V.; Brandes, N.; Germino, J.; Ntranos, V.; Ye, C. J.; Aguet, F.; Farh, K.
10.1101/2023.12.12.571130 — genomics — Posted on 2023-12-13
2540 The impact of PCR duplication on RNA-seq data generated using NovaSeq 6000, NovaSeq X, AVITI and G4 sequencers.
Zajac, N.; Vlachos, I.; Sajibu, S.; Opitz, L.; Wang, S.; Chittur, S.; Mason, C. E.; Knudtson, K. L.; Ashton, J. M.; Rehrauer, H.; Aquino, C.
10.1101/2023.12.12.571280 — genomics — Posted on 2023-12-13
2541 Genome-wide association study of delay discounting in Heterogenous Stock rats
Lara, M. K.; Chitre, A. S.; Chen, D.; Johnson, B. B.; Nguyen, K.-M.; Cohen, K. A.; Muckadam, S. A.; Lin, B.; Ziegler, S.; Beeson, A.; Solberg Woods, L. C.; Polesskaya, O.; Palmer, A. A.; Mitchell, S. H.
10.1101/2023.12.12.570851 — genomics — Posted on 2023-12-13
2542 Discovery of new endogenous viral elements in campoplegine wasps (Ichneumonidae, Campopleginae, Campoplex) suggests a widespread nudivirus domestication event
Cerqueira de Araujo, A.; Leobold, M.; Cariou, M.; Ferreira dos Santos, B.; Uzbekov, R.; Ricciardi, R.; Scaramozzino, P.; Lucchi, A.; Musset, K.; Drezen, J.-M.; Josse, T.; Huguet, E.
10.1101/2023.12.12.569846 — evolutionary biology — Posted on 2023-12-13
2543 Tertiary-interaction characters enable fast, model-based structural phylogenetics beyond the twilight zone
Puente-Lelievre, C.; Malik, A. J.; Douglas, J.; Ascher, D.; Baker, M.; Allison, J.; Poole, A. M.; Lundin, D.; Fullmer, M.; Bouckaert, R.; Steinegger, M.; Matzke, N. J.
10.1101/2023.12.12.571181 — evolutionary biology — Posted on 2023-12-13
2546 Paleocene origin of a streamlined digestive symbiosis in leaf beetles
Garcia-Lozano, M.; Henzler, C.; Porras, M. A. G.; Pons, I.; Berasategui, A.; Lanz, C.; Budde, H.; Oguchi, K.; Matsuura, Y.; Pauchet, Y.; Goffredi, S.; Fukatsu, T.; Salem, H.
10.1101/2023.12.12.571295 — evolutionary biology — Posted on 2023-12-13
2550 Differential developmental blueprints of organ-intrinsic nervous systems
Hsu, I.-U.; Lin, Y.; Guo, Y.; Xu, Q. J.; Shao, Y.; Wang, R. L.; Yin, D.; Zhao, J.; Young, L. H.; Zhao, H.; Zhang, L.; Chang, R. B.
10.1101/2023.12.12.571306 — neuroscience — Posted on 2023-12-13
2553 Distinct effects of priming the brain using tDCS and observational practice: new evidence from brain effective connectivity.
McLeod, J.; Chavan, A.; Lee, H.; Sattari, S.; Kurry, S.; Wake, M.; Janmohamed, Z.; Hodges, N. H.; Virji-Babul, N.
10.1101/2023.12.12.570884 — neuroscience — Posted on 2023-12-13
2554 ERK1/2 inhibition disrupts alcohol memory reconsolidation and prevents relapse
Rahamim, N.; Liran, M.; Aronovici, C.; Flumin, H.; Gordon, T.; Urshansky, N.; Barak, S.
10.1101/2023.12.12.571297 — neuroscience — Posted on 2023-12-13
2555 Dynamic evolution of infarct volumes at MRI in ischemic stroke due to large vessel occlusion
Munsch, F.; Planes, D.; Fukutomi, H.; Marnat, G.; Courret, T.; Micard, E.; Chen, B.; Seners, P.; Dubos, J.; Planche, V.; Coupe, P.; Dousset, V.; Lapergue, B.; Olivot, J.-M.; Sibon, I.; Thiebaut de Schotten, M.; Tourdias, T.
10.1101/2023.12.12.571221 — pathology — Posted on 2023-12-13
2558 ARID1A Mutations Protect Follicular Lymphoma from FAS-dependent Immune Surveillance by Reducing RUNX3/ETS1-Driven FAS-Expression
Antoniolli, M.; Solovey, M.; Strobl, C. D.; Bararia, D.; Keay, W. D.; Hildebrand, J. A.; Adolph, L.; Heide, M.; Passerini, V.; Freyholdt, T.; Wange, L.; Enard, W.; Thieme, S.; Blum, H.; Rudelius, M.; Mergner, J.; Ludwig, C.; Bultmann, S.; Schmidt-Supprian, M.; Leonardt, H.; Subklewe, M.; von Bergwelt-Baildon, M.; Colome-Tatche, M.; Weigert, O.
10.1101/2023.12.12.571212 — cancer biology — Posted on 2023-12-13
2559 Single-nucleotide-resolution genomic maps of O6-methylguanine from the glioblastoma drug temozolomide
Buechel, J.; Mingard, C.; Takhaveev, V.; Reinert, P. B.; Keller, G.; Kloter, T.; Huber, S.; McKeague, M.; Sturla, S. J.
10.1101/2023.12.12.571283 — cancer biology — Posted on 2023-12-13
2561 Identifying drug sensitivity of multifocal primary prostate cancer
Kang, J.; Chouvardas, P.; Ovchinnikova, K.; Thalmann, G. N.; Karkampouna, S.; Kruithof-de Julio, M.
10.1101/2023.12.12.569525 — cancer biology — Posted on 2023-12-13
2562 Fixed-target time-resolved crystallography at XFELs: the scourge of light contamination but reduced sample consumption
Gotthard, G.; Flores-Ibarra, A.; Carrillo, M.; Kepa, M. W.; Mason, T. J.; Stegmann, D. P.; Olasz, B.; Pachota, M.; Dworkowski, F.; Ozerov, D.; Pedrini, B. F.; Padeste, C.; Beale, J. H.; Nogly, P.
10.1101/2023.12.12.571218 — biophysics — Posted on 2023-12-13
2563 Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?
Scollo, F.; Tempra, C.; Evci, H.; Riopedre-Fernandez, M.; Olzynska, A.; Javanainen, M.; Uday, A.; Cebecauer, M.; Cwiklik, L.; Martinez-Seara, H.; Jungwirth, P.; Jurkiewicz, P.; Hof, M.
10.1101/2023.12.12.571079 — biophysics — Posted on 2023-12-13
2565 Amino acid characteristics in protein native state structures
Skrbic, T.; Giacometti, A.; Hoang, T. X.; Maritan, A.; Banavar, J. R.
10.1101/2023.12.12.571261 — biophysics — Posted on 2023-12-13
2566 Pan-cancer Analysis Reveals m6A Variation and Cell-specific Regulatory Network in Different Cancer Types
Lin, Y.; Li, J.; Liang, S.; Chen, Y.; Li, Y.; Cun, Y.; Tian, L.; Zhou, Y.; Chen, Y.; Chu, J.; Chen, H.; Luo, Q.; Zheng, R.; Wang, G.; Liang, H.; Cui, P.; An, S.
10.1101/2023.12.11.571179 — bioinformatics — Posted on 2023-12-13
2572 Involvement of FKBP5, but not of stress, in alcohol memory reconsolidation
Rahamim, N.; Aronovici, C.; Liran, M.; Goltseker, K.; Levin-Greenwald, M.; Heymann, T.; Hausch, F.; Barak, S.
10.1101/2023.12.12.570934 — neuroscience — Posted on 2023-12-13
2573 Neurophysiological mechanisms underlying post-stroke deficits in contralesional perceptual processing
Pearce, D. J.; Loughnane, G. M.; Chong, T. T.- J.; Demeyere, N.; Mattingley, J. B.; Moore, M. J.; New, P. W.; O'Connell, R. G.; O'Neill, M. H.; Rangelov, D.; Stolwyk, R. J.; Webb, S. S.; Zhou, S.-H.; Brosnan, M. B.; Bellgrove, M. A.
10.1101/2023.12.12.571233 — neuroscience — Posted on 2023-12-13
2576 VirtuousPocketome: A Computational Tool for Screening Protein-ligand Complexes to Identify Similar Binding Sites
Pallante, L.; Cannariato, M.; Androutsos, L.; Zizzi, E. A.; Bompotas, A.; Hada, X.; Grasso, G.; Kalogeras, A.; Mavroudi, S.; Di Benedetto, G.; Theofilatos, K.; Deriu, M. A.
10.1101/2023.12.12.571207 — bioengineering — Posted on 2023-12-13
2577 Single cell discovery of m6A RNA modifications in the hippocampus
Feng, S.; Tellaetxe-Abete, M.; Zhang, Y.; Peng, Y.; Zhou, H.; Larrea, E.; Xue, L.; Zhang, L.; Koziol, M. J.
10.1101/2023.12.06.570314 — neuroscience — Posted on 2023-12-13
2578 Senolytic Intervention Improves Cognition, Metabolism, and Adiposity in Female APPNL-F/NL-F Mice.
Fang, Y.; Peck, M. R.; Quinn, K.; Medina, D.; Roy, S.; McFadden, S. A.; Bartke, A.; Hascup, K. N.; Hascup, E. R.
10.1101/2023.12.12.571277 — neuroscience — Posted on 2023-12-13
2580 A computational study to assess the pathogenicity of single or combinations of missense variants on respiratory Complex I
Rigobello, L.; Lugli, F.; Caporali, L.; Bartocci, A.; Fadanni, J.; Zerbetto, F.; Iommarini, L.; Carelli, V.; Ghelli, A. M.; Musiani, F.
10.1101/2023.12.11.571090 — biophysics — Posted on 2023-12-13
2581 Mesenchymal Osr1+ cells regulate embryonic lymphatic vessel formation
Vallecillo Garcia, P.; Kühnlein, M. N.; Orgeur, M.; Hansmeier, N. R.; Kotsaris, G.; Timmermann, B.; Giesecke-Thiel, C.; Hägerling, R.; Stricker, S.
10.1101/2023.12.11.571189 — developmental biology — Posted on 2023-12-13
2583 The Cryptococcus extracellular vesicle transcriptome
Taheraly, A.; Maufrais, C.; Moyrand, F.; Coppee, J.-Y.; Colin, J.; Janbon, G.
10.1101/2023.12.08.570810 — microbiology — Posted on 2023-12-13
2585 Multi-omic characterization of ILC and ILC-like cell lines as part of ILC cell line encyclopedia (ICLE) defines new models to study potential biomarkers and explore therapeutic opportunities
Shah, O. S.; Chen, F.; Wedn, A.; Kashiparekh, A.; Savariau, L.; Clifford, B.; Hooda, J.; Christgen, M.; Atkinson, J. M.; Oesterreich, S.; Lee, A. V.
10.1101/2023.09.26.559548 — cancer biology — Posted on 2023-12-12
2586 Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors
Clayton, J.; Romany, A.; Matenoglou, E.; Gavathiotis, E.; Poulikakos, P. I.; Shen, J.
10.1101/2023.12.12.571293 — biophysics — Posted on 2023-12-12
2587 Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
Rodstrom, K. E. J.; Cloake, A.; Sormann, J.; Baronina, A.; Smith, K. H. M.; Pike, A. C. W.; Ang, J.; Proks, P.; Schewe, M.; Holland-Kaye, I.; Bushell, S. R.; Elliott, J.; Pardon, E.; Baukrowitz, T.; Owens, R. J.; Newstead, S.; Steyaert, J.; Carpenter, E. P.; Tucker, S. J.
10.1101/2023.10.19.562917 — biophysics — Posted on 2023-12-12
2592 Catalytically inactive dKbCas12d guided by sgRNA and new insights into its binding through a single-molecule approach
Alekseev, A.; Klimko, V.; Frantsuzova, I.; Abramova, M.; Vinnik, V.; Vasileva, A.; Selkova, P.; Khodorkovskii, M.; Arseniev, A.
10.1101/2023.12.12.571249 — biophysics — Posted on 2023-12-12
2593 Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states
Lin, D. Y.-w.; Kueffer, L. E.; Juneja, P.; Wales, T. E.; Engen, J. R.; Andreotti, A. H.
10.1101/2023.06.02.543453 — biophysics — Posted on 2023-12-12
2600 A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD
McCallister, T. X.; Lim, C. K. W.; Terpstra, W. M.; C., M. A. Z.; Zhang, S.; Powell, J. E.; Gaj, T.
10.1101/2023.12.12.571328 — bioengineering — Posted on 2023-12-12
2601 Lsr2, a pleiotropic regulator at the core of the infectious strategy of Mycobacterium abscessus
Gerges, E.; Rodriguez-Ordonez, M. d. P.; Durand, N.; Herrmann, J.-L.; Cremazy, F.
10.1101/2023.12.12.571305 — genomics — Posted on 2023-12-12
2604 Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie Bandavirus in aged ferrets
Jung, J. U.; Kim, D.; Kim, E.; Kim, S.; Chung, Y.; Cho, S.-D.; Choi, Y.; Lai, C.-J.; Dai, X.; Kang, S.; Kwak, M.-J.; Cha, I.; Liu, Z.; Choi, Y.; Park, S.-H.; Choi, Y. K.; Kim, S.
10.1101/2023.07.19.549761 — microbiology — Posted on 2023-12-12
2606 An arginine-rich nuclear localization signal (ArgiNLS) strategy for streamlined image segmentation of single-cells
Szelenyi, E. R.; Navarrete, J. S.; Murry, A. D.; Zhang, Y.; Girven, K. S.; Kuo, L.; Cline, M. M.; Bernstein, M. X.; Burdyniuk, M.; Bowler, B.; Goodwin, N. L.; Juarez, B.; Zweifel, L.; Golden, S.
10.1101/2023.11.22.568319 — neuroscience — Posted on 2023-12-12
2607 SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide (CGRP) signaling blockade reduces interleukin 6 (IL-6) release and weight loss in mouse models
Rahman, S. M.; Buchholz, D. W.; Imbiakha, B.; Jaeger, M. C.; Leach, J.; Osborn, R. M.; Birmingham, A. O.; Dewhurst, S.; Aguilar, H. C.; Luebke, A. E.
10.1101/2023.10.23.563669 — neuroscience — Posted on 2023-12-12
2608 The scheduling of adolescence with Netrin-1 and UNC5C
Hoops, D.; Kyne, R. F.; Salameh, S.; Avramescu, R. G.; MacGowan, D.; Ewing, E.; He, A. T.; Orsini, T.; Durand, A.; Popescu, C.; Zhao, J. M.; Schatz, K. C.; Lin, L.; Carroll, Q. E.; Liu, G.; Paul, M. J.; Flores, C.
10.1101/2023.01.19.521267 — neuroscience — Posted on 2023-12-12
2614 voyAGEr: free web interface for the analysis of age-related gene expression alterations in human tissues
Schneider, A. L.; Martins-Silva, R.; Kaizeler, A.; Saraiva-Agostinho, N.; Barbosa-Morais, N. L.
10.1101/2022.12.22.521681 — bioinformatics — Posted on 2023-12-12
2615 Membrane protein sequence features direct post-translational insertion
Kalinin, I. A.; Peled-Zehavi, H.; Barshap, A. B. D.; Tamari, S. A.; Weiss, Y.; Nevo, R.; Fluman, N.
10.1101/2023.12.12.571264 — biochemistry — Posted on 2023-12-12
2618 pIGLET: Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish
Lalonde, R. L.; Wells, H. H.; Kemmler, C. L.; Nieuwenhuize, S.; Lerma, R.; Burger, A.; Mosimann, C.
10.1101/2023.12.08.570868 — genetics — Posted on 2023-12-12
2624 Inhibition of hypoxia-inducible factors suppresses subretinal fibrosis
Shoda, C.; Lee, D.; Miwa, Y.; Yamagami, S.; Nakashizuka, H.; Nimura, K.; Okamoto, K.; Kawagishi, H.; Negishi, K.; Kurihara, T.
10.1101/2023.12.12.571193 — molecular biology — Posted on 2023-12-12
2625 Ku-binding motifs in RAG2, XLF, PAXX and MRI support functional redundancy during V(D)J recombination
Tadi, S. K.; Gesnik, A.; Frit, P.; Iehl, F.; Ropars, V.; Dingli, F.; Loew, D.; Calsou, P.; Callebaut, I.; Charbonnier, J.-B.; de Villartay, J.-P.
10.1101/2023.12.12.570754 — molecular biology — Posted on 2023-12-12
2626 Three-dimensional dipole orientation mapping with high temporal-spatial resolution using polarization modulation
Zhong, S.; Qiao, L.; Ge, X.; Xu, X.; Fu, Y.; Gao, S.; Zhanghao, K.; Hao, H.; Wang, W.; Li, M.; Xi, P.
10.1101/2023.12.12.571225 — molecular biology — Posted on 2023-12-12
2629 High-resolution ultrastructure and morphology of marine ammonia-oxidizing archaea Nitrosopumilus maritimus SCM1 revealed by Cryo-ET and STEM-EDS
Zhou, Y.; Yan, A.; Yang, J.; He, W.; Guo, S.; Li, Y.; Dai, Y.; Pan, X.; Cui, D.; Teng, W.; Pereira, O.; Bi, R.; Chen, S.; Fan, L.; Wang, P.; Liao, Y.; Qin, W.; Sui, S.-F.; Zhu, Y.; Zhang, C.; Liu, Z.
10.1101/2023.12.12.571259 — microbiology — Posted on 2023-12-12
2630 A Sensitivity Analysis of Methodological Variables Associated with Microbiome Measurements
Forry, S. P.; Servetas, S. L.; Dootz, J. N.; Hunter, M. E.; Kralj, J. G.; filliben, J. J.; Jackson, S. A.
10.1101/2023.12.12.571292 — microbiology — Posted on 2023-12-12
2631 Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin
Welsh, F. C.; Eguia, R. T.; Lee, J. M.; Haddox, H. K.; Galloway, J.; Vinh, N. V.; Loes, A. N.; Huddleston, J.; Yu, T. C.; Le, M. Q.; Nhat, N. T.; Thanh, N. T. L.; Greninger, A. L.; Chu, H. Y.; Englund, J. A.; Bedford, T.; Matsen, F. A.; Boni, M. F.; Bloom, J. D.
10.1101/2023.12.12.571235 — microbiology — Posted on 2023-12-12
2635 OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors
Sun, W.; Hughes, E. P.; Kim, H.; Perovanovic, J.; Charley, K. R.; Perkins, B.; Du, J.; Ibarra, A.; Syage, A. R.; Hale, J. S.; Williams, M. A.; Tantin, D.
10.1101/2022.09.21.508912 — immunology — Posted on 2023-12-12
2637 Role of Ribeye PXDLS/T-binding cleft in normal synaptic ribbon function
Zhu, J.; Lv, C.; Henry, D.; Viviano, S.; Santos-Sacchi, J.; Matthews, G.; Zenisek, D.
10.1101/2023.12.12.571266 — neuroscience — Posted on 2023-12-12
2638 Graded and sharp transitions in semantic function in left temporal lobe.
Krieger-Redwood, K.; Wang, X.; Souter, N. E.; Alam, T. R. d. J. G.; Smallwood, J.; Jackson, R.; Jefferies, E.
10.1101/2023.05.04.539459 — neuroscience — Posted on 2023-12-12
2639 Hippocampal ripples linked to recognition memory judgments in children
Norman, Y.; Dorfmuller, G.; Taussig, D.; Dorison, N.; Fohlen, M.; Chipaux, M.; Ferrand-Sorbets, S.; Bulteau, C.; Harel, M.; Malach, R.; Levy, M.
10.1101/2023.09.19.558300 — neuroscience — Posted on 2023-12-12
2640 Mucosal washes are useful for sampling intestinal mucus-associated microbiota despite low biomass
Martinez-Medina, J. N.; Ghazisaeedi, F.; Kramer, C.; Ziegler, J. F.; McParland, V.; Siegmund, B.; Jarquin-Diaz, V. H.; Fulde, M.; Forslund, S. K.
10.1101/2023.12.12.571228 — systems biology — Posted on 2023-12-12
2641 Genotype imputation in F2 crosses of inbred lines
Pierotti, S.; Welz, B.; Fitzgerald, T.; Wittbrodt, J.; Birney, E.
10.1101/2023.12.12.571258 — bioinformatics — Posted on 2023-12-12
2642 A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation
Bertran, M. T.; Walmsley, R.; Cummings, T. F. M.; Aramburu, I.; Benton, D. J.; Assalaarachchi, J.; Chasampalioti, M.; Swanton, T.; Joshi, D.; Federico, S.; Okkenhaug, H.; Yu, L.; Oxley, D.; Walker, S.; Papayannopoulos, V.; Suga, H.; Christophorou, M. A.; Walport, L. J.
10.1101/2023.12.12.571217 — biochemistry — Posted on 2023-12-12
2644 Membrane-embedded polar residues target membrane proteins for degradation by the quality control protease FtsH
Chai-Danino, M.; Ravensary, N.; Onyshchuk, T.; Plohn, M.; Barshap, A. B. D.; Bsoul, A.; Peled-Zehavi, H.; Fluman, N.
10.1101/2023.12.12.571171 — biochemistry — Posted on 2023-12-12
2645 ESM-Scan - a tool to guide amino acid substitutions
Oberdorfer, G.; Winkler, A.; Totaro, M.; Vide, U.; Zausinger, R.
10.1101/2023.12.12.571273 — biochemistry — Posted on 2023-12-12
2646 G6PD deficiency mediated impairment of iNOS and lysosomal acidification affecting phagocytotic clearance in microglia in response to SARS-CoV-2
Mondal, A.; Munan, S.; Saxena, I.; Mukherjee, S.; Upadhyay, P.; Gupta, N.; Dar, W.; Samanta, A.; Singh, S.; Pati, S.
10.1101/2023.12.12.570971 — cell biology — Posted on 2023-12-12
2650 A cyclic dipeptide for salinity stress alleviation and the trophic flexibility of an endophyte reveal niches in salt marsh plant-microbe interactions
Hung, S.-H. W.; Yeh, P.-H.; Huang, T.-C.; Huang, S.-Y.; Wu, I.-C.; Liu, C.-H.; Lin, Y.-H.; Chien, P.-R.; Huang, F.-C.; Ho, Y.-N.; Kuo, C.-H.; Hwang, H.-H.; Chiang, E.-P. I.; Huang, C.-C.
10.1101/2023.12.12.569982 — microbiology — Posted on 2023-12-12
2651 Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome
Ranum, J. N.; Ledwith, M. P.; Alnaji, F. G.; Diefenbacher, M.; Orton, R.; Sloan, E.; Guereca, M.; Feltman, E. M.; Smollett, K.; da Silva Filipe, A.; Conley, M.; Russell, A. B.; Brooke, C. B.; Hutchinson, E.; Mehle, A.
10.1101/2023.12.12.570638 — microbiology — Posted on 2023-12-12
2653 Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistance.
Prieto, A.; Miro, L.; Margolles, Y.; Bernabeu, M.; Salguero, D.; Merino, S.; Tomas, J.; Corbera, J. A.; Perez-Bosque, A.; Huttener, M.; Fernandez, L. A.; Juarez, A.
10.1101/2023.12.12.571265 — microbiology — Posted on 2023-12-12
2655 The complement pattern recognition molecule CL-11 promotes invasion and injury of respiratory epithelial cells by SARS-CoV-2.
Polycarpou, A.; Wagner-Gamble, T.; Greenlaw, R.; O'Neill, L. A.; Khan, H.; Malim, M. M.; Romano, M.; Smolarek, D.; Doores, K. J.; Wallis, R.; Klavinskis, L. S.; Sacks, S.
10.1101/2023.12.11.571109 — immunology — Posted on 2023-12-12
2656 miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity
Welle, T. M.; Rajgor, D.; Garcia, J. G.; Kareemo, D.; Zych, S. M.; Gookin, S. E.; Martinez, T. P.; Dell'Acqua, M. L.; Ford, C. P.; Kennedy, M. J.; Smith, K. R.
10.1101/2023.12.12.570420 — neuroscience — Posted on 2023-12-12
2659 Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Yabo, Y. A.; Moreno-Sanchez, P. M.; Pires-Afonso, Y.; Kaoma, T.; Nosirov, B.; Scafidi, A.; Ermini, L.; Lipsa, A.; Oudin, A.; Kyriakis, D.; Grzyb, K.; Poovathingal, S. K.; Poli, A.; Muller, A.; Toth, R.; Klink, B.; Berchem, G.; Berthold, C.; Hertel, F.; Mittelbronn, M.; Heiland, D. H.; Skupin, A.; Nazarov, P. V.; Niclou, S. P.; Michelucci, A.; Golebiewska, A.
10.1101/2023.03.05.531162 — cancer biology — Posted on 2023-12-12
2660 Imputation of label-free quantitative mass spectrometry-based proteomics data using self-supervised deep learning
Webel, H.; Niu, L.; Bach Nielsen, A.; Locard-Paulet, M.; Mann, M.; Juhl Jensen, L.; Rasmussen, S.
10.1101/2023.01.12.523792 — bioinformatics — Posted on 2023-12-12
2662 Longitudinal profiling of the pregnancy plasma proteome through organic solvent precipitation and nano LC-MS/MS
George, A. L.; Cook, E.; Smith, G. C. S.; Charnock-Jones, S. D.; O'Rahilly, S.; Reimann, F.; Gribble, F. M.; Kay, R. G.
10.1101/2023.12.11.571058 — biochemistry — Posted on 2023-12-12
2665 A translation proofreader of archaeal origin imparts multialdehyde stress tolerance to land plants
Kumar, P.; Roy, A.; Mukul, S. J.; Singh, A. K.; Singh, D. K.; Nalli, A.; Banerjee, P.; Babu, K. S. D.; Raman, B.; Kruparani, S. P.; Siddiqi, I.; Sankaranarayanan, R.
10.1101/2023.10.06.561280 — plant biology — Posted on 2023-12-12
2667 Cellular visualization of G-quadruplex RNA via fluorescence lifetime imaging microscopy
Robinson, J.; Stenspil, S. G.; Maleckaite, K.; Bartlett, M.; Di Antonio, M.; Vilar, R.; Kuimova, M.
10.1101/2023.05.07.539224 — biophysics — Posted on 2023-12-12
2668 BioKG: a comprehensive, high-quality biomedical knowledge graph for AI-powered, data-driven biomedical research
Zhang, Y.; Pan, F.; Sui, X.; Yu, K.; Li, K.; Tian, S.; Erdengasileng, A.; Han, Q.; Wang, W.; Wang, J.; Wang, J.; Sun, D.; Chung, H.; Zhou, J.; Zhou, E.; Lee, B.; Zhang, P.; Qiu, X.; Zhao, T.; Zhang, J.
10.1101/2023.10.13.562216 — bioinformatics — Posted on 2023-12-12
2669 Genetic Screen Identified Prmt5 as a Neuroprotection Target against Cerebral Ischemia
Wu, H.; Lv, P.; Wang, J.; Bennett, B.; Wang, J.; Li, P.; Peng, Y.; Hu, G.; Lin, J.
10.1101/2023.06.26.546470 — cell biology — Posted on 2023-12-12
2671 Extracellular Matrix Protein 1 Attenuates Hepatic Fibrosis by Inhibiting TSP-, ADAMTS-, and MMP-Mediated Latent TGF-β1 Activation
Link, F.; Li, Y.; Zhao, J.; Munker, S.; Fan, W.; Nwosu, Z.; Yao, Y.; Hammad, S.; Liebe, R.; Liu, H.; Shao, C.; Sun, B.; Torok, N. J.; Ding, H.; Ebert, M.; Weng, H.; Dijke, P. t.; Drasdo, D.; Dooley, S.; Wang, S.
10.1101/2023.12.12.571289 — cell biology — Posted on 2023-12-12
2672 Modeling the profibrotic microenvironment in vitro: model validation
Grigorieva, O.; Basalova, N.; Dyachkova, U.; Novoseletskaya, E.; Vigovskii, M.; Arbatskiy, M.; Kulebyakina, M.; Efimenko, A.
10.1101/2023.12.12.571237 — cell biology — Posted on 2023-12-12
2673 A YIPF5-GOT1A/B complex directs a transcription independent function of ATF6 in ER export
Cramer, P.; Yonemura, Y.; Behrendt, L.; Marszalek, A.; Sannai, M.; Durso, W.; Guenes, C.; Szafranski, K.; Nakamura, N.; Nasrashvili, T.; Mayer, J.; von Eyss, B.; Kaether, C.
10.1101/2023.12.12.569033 — cell biology — Posted on 2023-12-12
2674 Multiple, single trait GWAS and supervised machine learning reveal the genetic architecture of Fraxinus excelsior tolerance to ash dieback in Europe
Doonan, J. M.; Budde, K. B.; Kosawang, C.; Lobo, A.; Verbylaite, R.; Brealey, J. C.; Martin, M. D.; Pliura, A.; Thomas, K.; Konrad, H.; Seegmuller, S.; Liziniewicz, M.; Cleary, M.; Nemesio-Gorriz, M.; Fussi, B.; Kirisits, T.; Gilbert, M. T.; Heuertz, M.; Kjaer, E. D.; Nielsen, L. R.
10.1101/2023.12.11.570802 — plant biology — Posted on 2023-12-12
2677 Kinome focused CRISPR-Cas9 screens in African ancestry patient-derived breast cancer organoids identifies essential kinases and synergy of EGFR and FGFR1 inhibition.
Madorsky Rowdo, F. P.; Martini, R.; Ackermann, S. E.; Tang, C. P.; Tranquile, M.; Irizarry, A.; Us, I.; Alawa, O.; Moyer, J. E.; Sigouros, M.; Nguyen, J.; Assaad, M. A.; Cheng, E.; Ginter, P. S.; Manohar, J.; Stonaker, B.; Boateng, R.; Oppong, J. K.; Adjei, E. K.; Awuah, B.; Kyei, I.; Aitpillah, F. S.; Adinku, M. O.; Ankomah, K.; Osei-Bonsu, E. B.; Gyan, K. K.; Hoda, S.; Newman, L.; Mosquera, J. M.; Sboner, A.; Elemento, O.; Dow, L. E.; Davis, M. B.; Martin, M. L.
10.1101/2023.12.11.570465 — cancer biology — Posted on 2023-12-12
2678 Vitamin D attenuates diabetic myocardial injury via the Erbb4/ferroptosis axis
Song, H.; Miao, Y.; Zhang, Y.; Zhang, L.; Chen, H.; Tang, L.; Li, W.; Gu, C.; Li, X.
10.1101/2023.12.11.571190 — pharmacology and toxicology — Posted on 2023-12-12
2679 Utilizing Non-Invasive Prenatal Test Sequencing Data Resource for Human Genetic Investigation
Liu, S.; Huang, S.; Liu, Y.; Gu, Y.; Lin, X.; Zhu, H.; Liu, H.; Xu, Z.; Cheng, S.; Lan, X.; Li, L.; Chen, G.-B.; Li, H.; Xu, X.; Nielsen, R.; Davies, R.; Albrechtsen, A.; Qiu, X.; Jin, X.
10.1101/2023.12.11.570976 — bioinformatics — Posted on 2023-12-12
2680 scPharm: identifying pharmacological subpopulations of single cells for precision medicine in cancers
Tian, P.; Zheng, J.; Xu, Y.; Wu, T.; Chen, S.; Zhang, Y.; Zhang, B.; Qiao, K.; Fan, Y.; Ambrogio, C.; Wang, H.
10.1101/2023.12.11.571182 — bioinformatics — Posted on 2023-12-12
2681 Climate change has desynchronized insect and vegetation phenologies across Europe
Huang, Y.; Yu, C.; Huang, W.; Liu, Y.; Qi, M.; Bai, J.; Dong, Y.; Gascoigne, S.; Ciais, P.; Penuelas, J.; Salguero-Gomez, R.
10.1101/2023.12.11.571152 — ecology — Posted on 2023-12-12
2682 LncRNA Bigheart trans-activates gene expression in a feed forward mechanism that facilitates calcineurin-NFAT signaling in myocardial hypertrophy
Mangraviti, N.; Ruhle, F.; Kinet, V.; Hegenbarth, J.-C.; Dirkx, E.; Spano, G.; De Majo, F.; Peppas, P.; Martens, L.; Ghandi, S.; Colpaert, R.; Ruperez, C.; Olieslagers, S.; Falcao-Pires, I.; Calore, M.; Witten, A.; da Costa Martins, P.; Mayr, M.; Muller, O.; Stoll, M.; De Windt, L. J.
10.1101/2023.12.11.571094 — molecular biology — Posted on 2023-12-12
2685 Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to the human brain evolution
Ciuba, K.; Piotrowska, A.; Chaudhury, D.; Dunski, E.; Behr, R.; Soroczynska, K.; Czystowska-Kuzmicz, M.; Abbas, M.; Figiel, I.; Wlodarczyk, J.; Verkhratsky, A.; Niedbala, M.; Kaspera, W.; Wilczynski, B.; Pekowska, A.
10.1101/2023.12.12.570426 — neuroscience — Posted on 2023-12-12
2687 Dissecting the Impact of Maternal Androgen Exposure on Offspring Health through Targeting the Androgen Receptor in Developmental Programming
Lu, H.; Jiang, H.; Li, C.; Derisoud, E.; Zhao, A.; Eriksson, G.; Lindgren, E.; Pui, H.-p.; Risal, S.; Pei, Y.; Maxian, T.; Ohlsson, C.; Benrick, A.; Haider, S.; Stener-Victorin, E.; Deng, Q.
10.1101/2023.12.12.569558 — physiology — Posted on 2023-12-12
2688 Lanthanide Cathodophores for Multicolor Electron Microscopy
Abdul Rehman, S.; Conway, J. B.; Nichols, A.; Soucy, E. R.; Dee, A.; Stevens, K.; Merminod, S.; MacNaughton, I.; Curtis, A.; Prigozhin, M. B.
10.1101/2023.12.11.570835 — biophysics — Posted on 2023-12-12
2689 Efficient and accurate detection of viral sequences at single-cell resolution reveals novel viruses perturbing host gene expression
Luebbert, L.; Sullivan, D. K.; Carilli, M.; Eldjarn Hjorleifsson, K.; Winnett, A. V.; Chari, T.; Pachter, L.
10.1101/2023.12.11.571168 — bioinformatics — Posted on 2023-12-12
2691 Facile generation of biepitopic antibodies with intrinsic agonism for activating receptors in the tumor necrosis factor superfamily
Jhajj, H. S.; Schardt, J. S.; Khalasawi, N.; Yao, E. L.; Lwo, T. S.; Kwon, N.-Y.; O'Meara, R. L.; Desai, A. A.; Tessier, P. M.
10.1101/2023.12.11.571146 — bioengineering — Posted on 2023-12-12
2692 Glioma Cells Secrete Collagen VI to Facilitate Invasion
Cha, J.; Ding, E. A.; Carvalho, E. M.; Fowler, A.; Aghi, M. K.; Kumar, S.
10.1101/2023.12.12.571198 — bioengineering — Posted on 2023-12-12
2693 Single extracellular vesicle imaging and computational analysis identifiesinherent architectural heterogeneity
Kapoor, K. S.; Kalluri, R.; Kong, S.; Sugimoto, H.; Guo, W.; Boominathan, V.; Chen, Y.-L.; Biswal, S. L.; Terlier, T.; McAndrews, K.
10.1101/2023.12.11.571132 — bioengineering — Posted on 2023-12-12
2695 Single molecule studies of the native hair cell mechanosensory transduction complex
Clark, S.; Mitra, J.; Elferich, J.; Goehring, A.; Ge, J.; Ha, T.; Gouaux, E.
10.1101/2023.12.11.571162 — biochemistry — Posted on 2023-12-12
2697 Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz Syndrome patients provides insights into genotype-phenotype relations
van den Bersselaar, L. M.; de Wagenaar, N. P.; Odijk, H. J. H. M.; Stefens, S. J. M.; Reinhardt, D. P.; Roos-Hesselink, J. W.; Kanaar, R.; Verhagen, J. M. A.; Bruggenwirth, H. T.; Van De Laar, I. M. B. H.; van der Pluijm, I.; Essers, J.
10.1101/2023.12.11.571192 — genetics — Posted on 2023-12-12
2701 Environmental DNA captures the internal structure of a pond metacommunity
Cai, W.; Pichler, M.; Biggs, J.; Nicolet, P.; Ewald, N.; Griffiths, R. A.; Bush, A.; Leibold, M. A.; Hartig, F.; Yu, D. W.
10.1101/2023.12.12.571176 — ecology — Posted on 2023-12-12
2702 Whole transcriptome profiling of placental pathobiology in SARS-CoV-2 pregnancies identifies placental dysfunction signatures
Stylianou, N.; Sebina, I.; Matigian, N.; Deohler, H.; Monkman, J.; Rohl, J.; Allenby, M.; Nam, A.; Pan, L.; Rockstroh, A.; Sadeghirad, H.; Chung, K.; Sobanski, T.; O'Byrne, K.; Rebutini, P. Z.; Machado-Souza, C.; Stonoga, E. T. S.; Warkiani, M. E.; Salomon, C.; Short, K. R.; McClements, L.; de Noronha, L.; Huang, R. Y.-J.; Belz, G.; Guimaraes, F.; Clifton, V.; Kulasinghe, A.
10.1101/2023.01.20.524893 — developmental biology — Posted on 2023-12-12
2703 Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoids
Notoh, H.; Yamasaki, S.; Suzuki, N.; Suzuki, A.; Okamoto, S.; Kanematsu, T.; Suzuki, N.; Katsumi, A.; Kojima, T.; Matsushita, T.; Tamura, S.
10.1101/2023.12.11.571194 — cell biology — Posted on 2023-12-12
2705 Regulation of blood pressure by METTL3 via RUNX1b-eNOS pathway in endothelial cells
Li, B.; Zhang, Y.; Yang, X.; Lan, M.; Yuan, Z.; Li, S.; Liu, Y.; Han, C.; Ai, D.; Yang, Y.; Zhu, Y.
10.1101/2023.12.11.571191 — cell biology — Posted on 2023-12-12
2708 Boosting bactericidal immunity of a recombinant Mycobacterium smegmatis strain via zinc-dependent ribosomal proteins
Singh, S.; Kanzin, D.; Chavez, S.; Saavedra-Avila, N. A.; Ng, T.; Lukos, R.; Mayer, O.; Kim, J.; Chen, B.; Chen, M.; Porcelli, S.; Jacobs, W. R.; Tiwari, S.
10.1101/2023.12.11.571163 — microbiology — Posted on 2023-12-12
2709 Evolution of extended-spectrum β-lactamase-producing ST131 Escherichia coli at a single hospital over 15 years
Cho, S.-T.; Mills, E. G.; Griffith, M. P.; Nordstrom, H. R.; McElheny, C. L.; Harrison, L. H.; Doi, Y.; Van Tyne, D.
10.1101/2023.12.11.571174 — microbiology — Posted on 2023-12-12
2711 Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of S. aureus Infections
Jo, J.; Upadhyay, T.; Woods, E. C.; Park, K. W.; Pedowitz, N. J.; Jaworek-Korjakowska, J.; Wang, S.; Valdez, T. A.; Fellner, M.; Bogyo, M.
10.1101/2023.12.11.571116 — microbiology — Posted on 2023-12-12
2717 Best Paper awards lack transparency, inclusivity, and support for Open Science
Lagisz, M.; Rutkowska, J.; Aich, U.; Ross, R. M.; Santana, M. S.; Wang, J.; Trubanova, N.; Page, M. J.; Pua, A. A. Y.; Yang, Y.; Amin, B.; Martinig, A. R.; Barnett, A.; Surendran, A.; Zhang, J.; Borg, D. N.; Elisee, J.; Wrightson, J. G.; Nakagawa, S.
10.1101/2023.12.11.571170 — scientific communication and education — Posted on 2023-12-12
2719 Function-associated scRNA-seq on single lung cancer organoids unravels the immune landscape of tumor parenchyma
Liu, C.; Li, K.; Sui, X.; Zhao, T.; Zhang, T.; Chen, Z.; Wu, H.; Li, C.; Li, H.; Yang, F.; Liu, Z.; Lu, Y.-Y.; Wang, J.; Chen, X.; Liu, P.
10.1101/2023.12.11.571047 — cancer biology — Posted on 2023-12-12
2725 In Silico Evaluation of Cell Therapy in Acute versus Chronic Infarction: Role of Automaticity, Heterogeneity and Purkinje in Human
Riebel, L. L.; Wang, Z. J.; Martinez-Navarro, H.; Trovato, C.; Camps, J.; Berg, L. A.; Zhou, X.; Doste, R.; Sachetto Oliveria, R.; Weber dos Santos, R.; Biasetti, J.; Rodriguez, B.
10.1101/2023.12.11.570780 — bioengineering — Posted on 2023-12-12
2726 A Pan-respiratory Antiviral Chemotype Targeting a Host Multiprotein Complex
Michon, M.; Mueller-Schiffmann, A.; Lingappa, A. F.; Yu, S. F.; Du, L.; Deiter, F.; Mallesh, S.; Crabtree, J.; Lingappa, U. F.; Macieik, A.; Mueller, L.; Ostermann, P. N.; Andree, M.; Adams, O.; Schaal, H.; Hogan, R. J.; Tripp, R. A.; Appiah, U.; Anand, S. K.; Campi, T. W.; Ford, M. J.; Reed, J. C.; Lin, J.; Akintunde, O.; Copeland, K.; Nichols, C.; Petrouski, E.; Moreira, A. R.; Jiang, I.-t.; DeYarman, N.; Broce, S.; Brown, I.; Segal, I.; Goldsmith, D.; Lau, S.; Hong, S.; Asundi, V.; Briggs, E. M.; Phyo, N. S.; Froehlich, M.; Onisko, B.; Matlack, K.; Dey, D.; Lingappa, J. R.; Prasad, M. D.; K
10.1101/2021.01.17.426875 — biochemistry — Posted on 2023-12-12
2727 Modeling the critical MCOR-causing deletion in mouse unveils aberrant Sox21 expression in developing and adult iris and ciliary body, and implicates Tgfb2 in MCOR-associated glaucoma and myopia.
Angee, C.; Erjavec, E.; Hadjadj, D.; Passet, B.; David, P.; Kostic, C.; Dode, E.; Zanlonghi, X.; Cagnard, N.; Nedelec, B.; Crippa, S.; Bole-Feysot, C.; Zarhrate, M.; Castille, J.; Vilotte, J.-L.; Calvas, P.; Plaisancie, J.; Chassaing, N.; Kaplan, J.; Rozet, J.-M.; Fares Taie, L.
10.1101/2023.12.11.571097 — genetics — Posted on 2023-12-12
2728 Newly Sequenced Genomes Reveal Patterns of Gene Family Expansion in select Dragonflies (Odonata: Anisoptera)
Tolman, E. R.; Beatty, C. D.; Frandsen, P. B.; Bush, R. J.; Burchim, O. R.; Driever, E. S.; Harding, K. M.; Jordan, D.; Kohli, M. K.; Park, J.; Park, S.; Reyes, K.; Rosario, M.; Ryu, J. L.; Wade, V.; Ware, J. L.
10.1101/2023.12.11.569651 — evolutionary biology — Posted on 2023-12-12
2731 Gain of chromosome region 1q31.3 in human iPSCs confers growth advantage and alters contraction in derivative cardiomyocytes
Brandao, K. O.; Meraviglia, V.; Salvatori, D.; Cao, X.; Sala, L. P.; Yiangou, L.; Mol, M. P. H.; Bellin, M.; Mummery, C. L.; Davis, R. P.
10.1101/2023.12.11.571144 — cell biology — Posted on 2023-12-12
2732 Postnatal FGF-signalling establishes gradients of cell-identities along the proximal-distal axis of the lung airways
Sountoulidis, A.; Firsova, A. B.; Liontos, A.; Theelke, J.; Koepke, J.; Millar-Buchner, P.; Manneras-Holm, L.; Bjorklund, A. K.; Fysikopoulos, A.; Gaengel, K.; Backhed, F.; Betsholtz, C.; Seeger, W.; Bellusci, S.; Samakovlis, C.
10.1101/2023.12.11.571142 — cell biology — Posted on 2023-12-12
2733 Transposable elements may enhance antiviral resistance in HIV-1 elite controllers
Singh, M.; Leddy, S. M.; Iniguez, L. P.; Bendall, M. L.; Feschotte, C.; Nixon, D. F.
10.1101/2023.12.11.571123 — immunology — Posted on 2023-12-12
2735 Too much or not enough? Optimal level of human intracranial theta activity for rule-switching in the subthalamo-medio-prefrontal circuit
Laquitaine, M.; polosan, m.; Kahane, p.; Chabardes, s.; yelnick, j.; Fernandez-Vidal, S.; domenech, p.; Bastin, J.
10.1101/2023.12.11.571129 — neuroscience — Posted on 2023-12-12
2736 Model Based Inference of Synaptic Plasticity Rules
Mehta, Y.; Tyulmankov, D.; Rajagopalan, A. E.; Turner, G. C.; Fitzgerald, J. E.; Funke, J.
10.1101/2023.12.11.571103 — neuroscience — Posted on 2023-12-12
2737 Can structure predict function at individual level in the human connectome?
Smolders, L.; De Baene, W.; Rutten, G.-J.; van der Hofstad, R.; Florack, L.
10.1101/2023.12.11.568977 — neuroscience — Posted on 2023-12-12
2740 Decision Characteristics Underlying Non-Suicidal Self-Injury in Patients with Major Depressive Disorder
Lu, Y.-L.; Ge, Y.; Li, M.; Liang, S.; Zhang, X.; Sui, Y.; Yang, L.; Song, P.; Zhang, Y.; Zhang, H.; Yan, H.
10.1101/2023.12.10.570987 — neuroscience — Posted on 2023-12-12
2742 Tropical Race 4 and Race 1 strains causing Fusarium wilt of banana infect and survive in Heliconia species and ornamental bananas
Martinez de la Parte, E.; Meijer, H. J. G.; Guzman Quesada, M.; Carr Rodriguez, C.; Masis Jimenez, S.; Perez Vicente, L.; Kema, G. H. J.
10.1101/2023.12.11.571145 — plant biology — Posted on 2023-12-12
2744 Prediction of DNA i-Motifs Via Machine Learning
Yang, B.; Guneri, D.; Yu, H.; Wright, E.; Chen, W.; Waller, Z. A. E.; DING, Y.
10.1101/2023.12.11.571121 — bioinformatics — Posted on 2023-12-12
2747 An interactive web application for exploring human plasma and fibroblast metabolomics data from patients with inborn errors of metabolism
Cai, L.; Hieu, V.; Gu, W.; Chen, H.; Franklin, J.; Abou Haidar, L.; Wu, Z.; Pan, C.; Cai, F.; Nguyen, P.; Ko, B.; Yang, C.; Zacharias, L. G.; Sudderth, J.; Montgomery, S.; Uhles, C.; Fisher, H.; Hudnall, J.; Hornbuckle, C.; Quinn, C.; Michel, D.; Umana, L.; Scheuerle, A.; McNutt, M.; Gotway, G.; Afroze, B.; Ni, M.; DeBerardinis, R. J.
10.1101/2023.12.11.571124 — bioinformatics — Posted on 2023-12-12
2752 Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling
Yuen, Z.; Shanmuganandam, S.; Stanley, M.; Jiang, S.; Hein, N.; Daniel, R.; McNevin, D.; Jack, C.; Eyras, E.
10.1101/2023.12.10.571037 — genomics — Posted on 2023-12-12
2756 "Flower power": how flowering affects spectral diversity metrics and their relationship with plant diversity
Perrone, M.; Conti, L.; Galland, T.; Komarek, J.; Lagner, O.; Torresani, M.; Rossi, C.; Carmona, C. P.; de Bello, F.; Rocchini, D.; Moudry, V.; Simova, P.; Bagella, S.; Malavasi, M.
10.1101/2023.12.11.571067 — ecology — Posted on 2023-12-12
2757 Forest demography and biomass accumulation rates are associated with transient mean tree size vs density scaling relations
Yu, K.; Chen, H. Y. H.; Gessler, A.; Pugh, T. A. M.; Searle, E. B.; Allen, R. B.; Pretzsch, H.; Ciais, P.; Phillips, O. L.; Brienen, R. J. W.; Chu, C.; Xie, S.; Ballantyne, A. P.
10.1101/2023.12.11.571032 — ecology — Posted on 2023-12-12
2759 Biased cell adhesion organizes a circuit for visual motion integration
Carrier, Y.; Quintana Rio, L.; Formicola, N.; de Sousa-Xavier, V.; Tabet, M.; Chen, Y.-C. D.; Orts, L.; Wislez, M.; Pinto-Teixeira, F.
10.1101/2023.12.11.571076 — developmental biology — Posted on 2023-12-12
2762 Cold Atmospheric Helium Plasma In The Post-Covid Era: A Promising Tool For The Disinfection Of Silicone Endotracheal Prostheses
Silva, D. M. d.; Nascimento, F. d.; Milhan, N. V.; Oliveira, M. A. C. d.; Cardoso, P. F. G.; Legendre, D.; Aoki, F. G.; Kostov, K. G.; Koga-Ito, C. Y.
10.1101/2023.12.10.570744 — microbiology — Posted on 2023-12-12
2763 Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3
Watchon, M.; Robinson, K. J.; Luu, L.; An, Y.; Yuan, K.; Plenderleith, S. K.; Cheng, F.; Don, E. K.; Nicholson, G.; Lee, A.; Laird, A. S.
10.1101/2021.04.30.442119 — neuroscience — Posted on 2023-12-12
2764 Towards fNIRS Hyperfeedback: A Feasibility Study on Real-Time Interbrain Synchrony
Kostorz, K.; Nguyen, T.; Pan, Y.; Melinscak, F.; Steyrl, D.; Hu, Y.; Sorger, B.; Hoehl, S.; Scharnowski, F.
10.1101/2023.12.11.570765 — neuroscience — Posted on 2023-12-12
2765 Unveiling interactions of spatial-temporal information in tactile motion perception
Qu, B.; Tan, X.; Tang, Z.; Friedman, R. M.; Wang, H.; Lan, L.; Schriver, K. E.; Pan, G.; Lai, H.-Y.
10.1101/2023.12.11.571089 — neuroscience — Posted on 2023-12-12
2769 Inhibition of KLK8 promotes pulmonary endothelial repair by restoring VE-cadherin/Akt/FOXM1 pathway
Zhao, Y.; Ji, H.; Han, F.; Xu, Q.; Zhang, H.; Liu, D.; Wei, J.; Xu, D.; Jiang, L.; Du, J.; Xu, P.; Liu, Y.; Zhu, X.
10.1101/2023.12.06.570377 — physiology — Posted on 2023-12-12
2771 YAP/TAZ enhance P-body formation to promote tumorigenesis
Shen, X.; Peng, X.; Guo, Y.; Dai, Z.; Cui, L.; Yu, W.; Liu, Y.; Liu, C.-Y.
10.1101/2023.06.02.542626 — cell biology — Posted on 2023-12-12
2772 Fatty Acid Metabolism and The Oxidative Stress Response Support Bacterial Predation
Jain, R.; Le, N.-H.; Bertaux, L.; Baudry, J.; Bibette, J.; Denis, Y.; Habermann, B. H.; Mignot, T.
10.1101/2023.12.11.571100 — microbiology — Posted on 2023-12-12
2774 A Cardiac Transcriptional Enhancer is Repurposed During Regeneration to Activate an Anti-proliferative Program
Rao, A.; Russell, A.; Segura-Bermudez, J.; Franz, C.; Blatnik, A.; Panten, J.; Zevallos, M.; Pietrzak, M.; Goldman, J. A.
10.1101/2023.06.30.547239 — developmental biology — Posted on 2023-12-12
2775 A universal preservation protocol for multi-omic and histological analysis of kidney tissue
Gies, S. E.; Hänzelmann, S.; Kylies, D.; Lagies, S.; Lasse, M.; Hausmann, F.; Khatri, R.; Poets, M.; Zhang, T.; Lu, S.; Liu, S.; Chilla, S.; Edenhofer, I.; Czogalla, J.; Braun, F.; Kammerer, B.; Rinschen, M. M.; Puelles, V. G.; Bonn, S.; Lindenmeyer, M.; Huber, T. B.
10.1101/2023.08.16.553482 — genomics — Posted on 2023-12-12
2776 Microtubule association of TRIM3 revealed by differential extraction proteomics
Glover, H.; Mendes, M.; Gomes-Neto, J.; Ruscilowicz-Jones, E. V.; Rigden, D.; Dittmar, G.; Urbe, S.; Clague, M. J.
10.1101/2023.07.27.549915 — cell biology — Posted on 2023-12-12
2777 Nanopore sequencing for accurate bacterial outbreak tracing
Lohde, M.; Wagner, G. E.; Dabernig-Heinz, J.; Viehweger, A.; Braun, S. D.; Monecke, S.; Diezel, C.; Stein, C.; Marquet, M.; Ehricht, R.; Pletz, M. W.; Brandt, C.
10.1101/2023.09.15.556300 — molecular biology — Posted on 2023-12-12
2778 Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa CF clinical isolates
Pedersen, B. H.; Simoes, F.; Pogrebnyakov, I.; Welch, M.; Johansen, H. K.; Molin, S.; La Rosa, R.
10.1101/2023.04.17.537125 — microbiology — Posted on 2023-12-12
2779 The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples
Vladimirov, N.; Voigt, F.; Naert, T.; Araujo, G. R.; Cai, R.; Reuss, A. M.; Zhao, S.; Schmid, P.; Hildebrand, S.; Schaettin, M.; Groos, D.; Mateos, J. M.; Bethge, P.; Yamamoto, T.; Aerne, V.; Roebroeck, A.; Ertürk, A.; Aguzzi, A.; Ziegler, U.; Stoeckli, E. T.; Baudis, L.; Lienkamp, S. S.; Helmchen, F.
10.1101/2023.06.16.545256 — neuroscience — Posted on 2023-12-12
2780 Assessing Perceptual Chromatic Equiluminance Using a Reflexive Pupillary Response
Ye, L.; Mahony, B. W.; Wang, X.; Daye, P.; Wang, W.; Cavanagh, P.; Pouget, P.; Andolina, I. M.
10.1101/2023.10.19.563116 — neuroscience — Posted on 2023-12-12
2783 Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response
Nyirenda, J.; Hardy, O.; Silva Filho, J. L.; Herder, V.; Attipa, C.; Ndovi, C.; Siwombo, M.; Namalima, T.; Suwedi, L.; Nyasulu, W.; Ngulube, T.; Nyirenda, D.; Mvaya, L.; Phiri, J.; Chasweka, D.; Eneya, C.; Makwinja, C.; Phiri, C.; Ziwoya, F.; Tembo, A.; Makwangwala, K.; Khoswe, S.; Banda, P.; Morton, B.; Hilton, O.; Lawrence, S.; Frere dos Reis, M.; Cardoso Melo, G.; Vinicious Guimaros de Lecerda, M.; Trindande Maranhao Costa, F.; Marcelo Monteiro, W.; Carlos de Lima Fereirra, L.; Johnson, C.; Mcguinness, D.; Jambo, K.; Haley, M. J.; Kumwenda, B.; Palmarini, M.; Barnes, K. G.; Denno, D. M.; Vo
10.1101/2023.11.16.566964 — immunology — Posted on 2023-12-12
2785 Cortical Plasticity is associated with Blood-Brain-Barrier Modulation
Swissa, E.; Monsonego, U.; Yang, L. T.; Schori, L.; Kamintsky, L.; Mirloo, S.; Burger, I.; Uzzan, S.; Patel, R.; Sudmant, P. H.; Prager, O.; Kaufer, D.; Friedman, A.
10.1101/2023.04.23.537964 — neuroscience — Posted on 2023-12-12
2791 Healthy microbiome - moving towards functional interpretation
Zielinska, K.; Udekwu, K.; Rudnicki, W.; Frolova, A.; Kosciolek, T.; Labaj, P. P.
10.1101/2023.12.04.569909 — bioinformatics — Posted on 2023-12-12
2794 A Gold Standard for Transcription Factor Regulatory Interactions in Escherichia coli K-12: Architecture of Evidence Types
Lara, P.; Gama-Castro, S.; Salgado, H.; Rioualen, C.; Tierrafria, V. H.; Muniz-Rascado, L. J.; Bonavides-Martinez, C.; Collado-Vides, J.
10.1101/2023.02.25.530038 — genomics — Posted on 2023-12-11
2798 Water wisteria genome reveals environmental adaptation and heterophylly regulation in amphibious plants
Li, G.; Zhao, X.; Yang, J.; Hu, S.; Ponnu, J.; Kimura, S.; Hwang, I.; Torii, K. U.; Hou, H.
10.1101/2022.09.19.508473 — plant biology — Posted on 2023-12-12
2802 Complete genomic assembly of Mauritian cynomolgus macaque killer immunoglobulin-like receptor and natural killer group 2 haplotypes
Prall, T. M.; Karl, J. A.; Varghese, J. M.; Baker, D. A.; Minor, N. R.; Raveendran, M.; Harris, R. A.; Rogers, J.; Wiseman, R. W.; O'Connor, D. H.
10.1101/2023.12.10.570943 — genomics — Posted on 2023-12-12
2805 Molecular Characterization of the Sea Lamprey Retina Illuminates the Evolutionary Origin of Retinal Cell Types
Wang, J.; Zhang, L.; Cavallini, M.; Pahlevan, A.; Sun, J.; Morshedian, A.; Fain, G. L.; Sampath, A. P.; Peng, Y.-R.
10.1101/2023.12.10.571000 — evolutionary biology — Posted on 2023-12-12
2806 Competition for shared resources increases dependence on initial population size during coalescence of gut microbial communities
Goldman, D. A.; Xue, K. S.; Parrott, A. B.; Jeeda, R. R.; Franzese, L. R.; Lopez, J. G.; Vila, J. C.; Petrov, D. A.; Good, B. H.; Relman, D. A.; Huang, K. C.
10.1101/2023.11.29.569120 — ecology — Posted on 2023-12-11
2807 Airborne eDNA captures three decades of ecosystem biodiversity
Sullivan, A. R.; Karlsson, E.; Svensson, D.; Brindefalk, B.; Antonio Villegas, J.; Mikko, A.; Bellieny, D.; Siddique, A. B.; Johansson, A.-M.; Grahn, H.; Sundell, D.; Norman, A.; Esseen, P.-A.; Sjodin, A.; Singh, N. J.; Brodin, T.; Forsman, M.; Stenberg, P.
10.1101/2023.12.06.569882 — ecology — Posted on 2023-12-11
2808 Regional estimates of gross primary production applying the Process-Based Model 3D-CMCC-FEM vs. Remote-Sensing multiple datasets
Dalmonech, D.; Vangi, E.; Chiesi, M.; Chirici, G.; Fibbi, L.; Giannetti, F.; Marano, G.; Massari, C.; Nole, A.; Xiao, J.; Collalti, A.
10.1101/2023.06.13.544712 — ecology — Posted on 2023-12-11
2813 pan-MHC and cross-Species Prediction of T Cell Receptor-Antigen Binding
Han, Y.; Yang, Y.; Tian, Y.; Fattah, F. J.; Itzstein, M. S. v.; Zhang, M.; Kang, X.; Yang, D. M.; Liu, J.; Xue, Y.; Liang, C.; Raman, I.; Zhu, C.; Xiao, O.; Hu, Y.; Dowell, J. E.; Homsi, J.; Rashdan, S.; Yang, S.; Gwin, M. E.; Hsiehchen, D.; Gloria-McCutchen, Y.; Pan, K.; Wu, F.; Gibbons, D.; Wang, X.; Yee, C.; Huang, J.; Reuben, A.; Cheng, C.; Zhang, J.; Gerber, D. E.; Wang, T.
10.1101/2023.12.01.569599 — immunology — Posted on 2023-12-12
2814 Activation of the P2RX7/IL-18 pathway in immune cells attenuates lung fibrosis
Janho dit Hreich, S.; Juhel, T.; Leroy, S.; Brau, F.; Hofman, V.; Hofman, P.; Vouret-Craviari, V.
10.1101/2022.12.15.520590 — immunology — Posted on 2023-12-12
2817 Subthalamic nucleus neurons encode syllable sequence and phonetic characteristics during speech
Lipski, W.; Bush, A.; Chrabaszcz, A.; Crammond, D. J.; Fiez, J. A.; Turner, R. S.; Richardson, M.
10.1101/2023.12.11.569290 — neuroscience — Posted on 2023-12-12
2819 Prior probability cues bias sensory encoding with increasing task exposure
Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.
10.1101/2023.07.15.549123 — neuroscience — Posted on 2023-12-12
2820 The immunosuppressive Tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4+ T cells
Cronin, S.; de Vries-Egan, A.; Vahlas, Z.; Czernikier, A.; Melucci, C.; Gerber, P. P.; ONeil, T.; Gloss, B.; Sharabas, M.; Turk, G.; Verollet, C.; Balboa, L.; Palmer, S.; Duette, G. A.
10.1101/2023.12.05.570223 — pathology — Posted on 2023-12-12
2821 Inducible mucosa-like differentiation of head and neck cancer cells drives the epigenetically determined loss of cell malignancy
Oppel, F.; Gendreizig, S.; Martinez-Ruiz, L.; Florido, J.; Lopez-Rodriguez, A.; Pabla, H.; Loganathan, L.; Hose, L.; Kuehnel, P.; Schmidt, P.; Schuermann, M.; Neumann, J. M.; Viyof Ful, F.; Scholtz, L. U.; Ligum, D.; Brasch, F.; Niehaus, K.; Escames, G.; Busche, T.; Kalinowski, J.; Goon, P.; Sudhoff, H.
10.1101/2023.06.30.547265 — cancer biology — Posted on 2023-12-11
2822 The Geometric Basis of Epithelial Convergent Extension
Brauns, F.; Claussen, N.; Wieschaus, E.; Shraiman, B. I.
10.1101/2023.05.30.542935 — biophysics — Posted on 2023-12-11
2823 A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.
Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Shepherd, D. P.; Presse, S. P.
10.1101/2023.12.07.570701 — biophysics — Posted on 2023-12-11
2824 Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.
Galvao Ferrarini, M.; Vallier, A.; Vincent-Monegat, C.; Dell'Aglio, E.; Gillet, B.; Hughes, S.; Hurtado, O.; Condemine, G.; Zaidman-Remy, A.; Rebollo, R.; Parisot, N.; Heddi, A.
10.1101/2023.04.03.535335 — bioinformatics — Posted on 2023-12-12
2825 Variability in single-cell oxygen consumption kinetics
Botte, E.; Cui, Y.; Magliaro, C.; Tenje, M.; Koren, K.; Rinaldo, A.; Stocker, R.; Behrendt, L.; Ahluwalia, A. D.
10.1101/2023.12.06.570361 — bioengineering — Posted on 2023-12-11
2829 The NeuroML ecosystem for standardized multi-scale modeling in neuroscience
Sinha, A.; Gleeson, P.; Marin, B.; Dura-Bernal, S.; Panagiotou, S.; Crook, S.; Cantarelli, M.; Cannon, R. C.; Davison, A. P.; Gurnani, H.; Silver, R. A.
10.1101/2023.12.07.570537 — neuroscience — Posted on 2023-12-11
2831 A pilot study of the comparison using a standard and individual altitude exposure protocol in elite gymnasts
Grushin, A.; Zelenkova, I.; Ilin, D.; Zotkin, S.; Korneev, P.; Koprov, S.; Almyashev, D.; Badtieva, V.; Glazachev, O.
10.1101/2023.12.08.569719 — physiology — Posted on 2023-12-11
2833 DNA-m6A calling and integrated long-read epigenetic and genetic analysis with fibertools
Jha, A.; Bohaczuk, S. C.; Mao, Y.; Ranchalis, J.; Mallory, B. J.; Min, A. T.; Hamm, M. O.; Swanson, E.; Dubocanin, D.; Finkbeiner, C.; Li, T.; Whittington, D.; Noble, W. S.; Stergachis, A. B.; Vollger, M. R.
10.1101/2023.04.20.537673 — bioinformatics — Posted on 2023-12-11
2836 Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation
Hossain, M. I.; Lee, J. H.; Gagne, J.-P.; Khan, J.; Poirier, G. G.; KIng, P. H.; Dawson, V. L.; Dawson, T. M.; Anadrabi, S. A.
10.1101/2023.05.30.542910 — neuroscience — Posted on 2023-12-11
2841 Loss of Nkd1 is dominant over loss of Axin2 in regulating Wnt signaling
Bell, I.; Khan, H.; Stutt, N.; Horn, M.; Hydzik, T.; Lum, W.; Rea, V.; Clapham, E.; Hoeg, L.; Van Raay, T. J.
10.1101/2023.10.30.563773 — developmental biology — Posted on 2023-12-11
2842 Subcortical correlates of consciousness with human single neuron recordings
Pereira, M.; Faivre, N.; Bernasconi, F.; Brandmeir, N.; Suffridge, J.; Tran, K.; Wang, S.; Finomore, V.; Konrad, P.; Rezai, A.; Blanke, O.
10.1101/2023.01.27.525684 — neuroscience — Posted on 2023-12-11
2845 Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity
Aguzzoli Heberle, B.; Brandon, J. A.; Page, M. L.; Nations, K. A.; Dikobe, K. I.; White, B. J.; Gordon, L. A.; Fox, G. A.; Wadsworth, M. E.; Doyle, P. H.; Williams, B. A.; Fox, E. J.; Shantaraman, A.; Ryten, M.; Goodwin, S.; Ghiban, E.; Wappel, R.; Mavruk-Eskpelivan, S.; Miller, J. B.; Seyfried, N.; Nelson, P. T.; Fryer, J. D.; Ebbert, M. T. W.
10.1101/2023.08.06.552162 — genomics — Posted on 2023-12-11
2846 Label-free imaging of DNA interactions with 2D materials
Suelzle, J.; Yang, W.; Shimoda, Y.; Ronceray, N.; Mayner, E.; Manley, S.; Radenovic, A.
10.1101/2023.07.05.547763 — biophysics — Posted on 2023-12-11
2847 Chemical defences indicate distinct colour patterns with reduced variability in aposematic nudibranchs
van den Berg, C. P.; Santon, M.; Endler, J. A.; Drummond, L.; Dawson, B. R.; Santiago, C.; Weber, N.; Cheney, K. L.
10.1101/2023.01.30.525844 — animal behavior and cognition — Posted on 2023-12-11
2849 Genetic Screen Identified Prmt5 as a Neuroprotection Target against Cerebral Ischemia
Wu, H.; Lv, P.; Wang, J.; Bennett, B.; Wang, J.; Li, P.; Peng, Y.; Hu, G.; Lin, J.
10.1101/2023.06.26.546470 — cell biology — Posted on 2023-12-11
2850 Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota
Carasso, S.; Zaatry, R.; Hajjo, H.; Kadosh-Kariti, D.; Ben-Assa, N.; Naddaf, R.; Mandelbaum, N.; Pressman, S.; Chowers, Y.; Gefen, T.; Jeffrey, K. L.; Jofre, J.; Coyne, M. J.; Comstock, L. E.; Sharon, I.; Geva-Zatorsky, N.
10.1101/2023.03.31.535104 — microbiology — Posted on 2023-12-11
2852 Healthy microbiome - moving towards functional interpretation
Zielinska, K.; Udekwu, K.; Rudnicki, W.; Kosciolek, T.; Frolova, A.; Labaj, P. P.
10.1101/2023.12.04.569909 — bioinformatics — Posted on 2023-12-11
2855 Larval growth rate affects wing shape more than eyespot size in the seasonally polyphenic butterfly Melanitis leda
Molleman, F.; Moore, E. M.; Halali, S.; Halali, D.; Kodandaramaiah, U.; van Bergen, E.; Brakefield, P. M.; Oostra, V.
10.1101/2023.12.11.571078 — evolutionary biology — Posted on 2023-12-11
2856 Subspecies divergence, hybridisation and the spatial environment shape phylosymbiosis in the microbiome of house mice
Ferreira, S. C. M.; Jarquin-Diaz, V. H.; Planillo, A.; Dureje, L.; Martincova, I.; Kramer-Schadt, S.; Forslund, S. K.; Heitlinger, E.
10.1101/2023.12.11.571054 — evolutionary biology — Posted on 2023-12-11
2864 Restoring Protein Glycosylation with GlycoShape
Ives, C. M.; Singh, O.; D'Andrea, S.; Fogarty, C. A.; Harbison, A. M.; Satheesan, A.; Tropea, B.; Fadda, E.
10.1101/2023.12.11.571101 — biophysics — Posted on 2023-12-11
2866 Structural mechanism of angiogenin activation by the ribosome
Loveland, A. B.; Koh, C. S.; Ganesan, R.; Jacobson, A.; Korostelev, A. A.
10.1101/2023.12.11.570495 — biochemistry — Posted on 2023-12-11
2867 A transient but very intense mutational burst occurs during the normal development of yeast colonies
Agier, N.; Vittorelli, N.; Chaux, F.; Gillet-Markowska, A.; O'Donnell, S.; Fischer, G.; Delmas, S.
10.1101/2023.12.11.571082 — genetics — Posted on 2023-12-11
2868 Characterization of Streptococcus uberis Cas9 (SuCas9) - a Type II-A Ortholog Functional in Human Cells
Selkova, P.; Vasileva, A.; Arseniev, A.; Abramova, M.; Musharova, O.; Malysheva, P.; Khodorkovskii, M.; Severinov, K.
10.1101/2023.12.11.571105 — molecular biology — Posted on 2023-12-11
2870 Degenerate PCR primers for potexvirus detection in seagrasses
Lim, S. J.; Rosario, K.; Kernbach, M. E.; Gross, A. J.; Furman, B. T.; Breitbart, M.
10.1101/2023.12.11.571111 — microbiology — Posted on 2023-12-11
2871 Virus-encoded Shemin pathway highlights the importance of tetrapyrrole metabolism during host infection
Wegner, H.; Roitman, S.; Kupczok, A.; Braun, V.; Woodhouse, J.; Grossart, H.-P.; Zehner, S.; Beja, O.; Frankenberg-Dinkel, N.
10.1101/2023.12.11.571061 — microbiology — Posted on 2023-12-11
2872 A metabolic modeling-based framework for predicting trophic dependencies in native rhizobiomes of crop plants
Ginatt, A. A.; Berihu, M.; Castel, E.; Medina, S.; Carmi, G.; Doron-Faigenboim, A.; Sharon, I.; Tal, O.; Droby, S.; Somera, T.; Mazzola, M.; Eizenberg, H.; Freilich, S.
10.1101/2023.12.11.571117 — microbiology — Posted on 2023-12-11
2874 Methylmercury demethylation and volatilization by animals expressing microbial enzymes.
Tepper, K.; King, J.; Cholan, P. M.; Pfitzner, C.; Morsch, M.; Apte, S.; Maselko, M.
10.1101/2023.12.11.571038 — synthetic biology — Posted on 2023-12-11
2880 Vitamin B5 Metabolism is Essential for Vacuolar and Mitochondrial Integrity and Xenobiotic Detoxification in Fungi
Choi, J.-Y.; Gihaz, S.; Munshi, M.; Singh, P.; Vydyam, P.; Hamel, P.; Adams, E. M.; Fuller, K.; Ben Mamoun, C.
10.1101/2023.12.10.571002 — microbiology — Posted on 2023-12-11
2881 Brain-wide activity-identity mapping of neural networks associated with prosocial motivation in rats
Ruzal, K.; Trachtenberg, E.; Kantor, B.; Flumin, H.; Roemer, A.; Crespo, A.; Kohl, J.; Ben-Ami Bartal, I.
10.1101/2023.12.10.570980 — neuroscience — Posted on 2023-12-11
2883 Alpha-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinsons disease
Geibl, F. F.; Henrich, M. T.; Xie, Z.; Zampese, E.; Tkatch, T.; Wokosin, D. L.; Nasiri, E.; Grotmann, C. A.; Dawson, V. L.; Dawson, T. M.; Chandel, N. S.; Oertel, W. H.; Surmeier, D. J.
10.1101/2023.12.11.571045 — neuroscience — Posted on 2023-12-11
2889 HGNNPIP: A Hybrid Graph Neural Network framework for Protein-protein Interaction Prediction
Chi, L.; Ma, J.; Wan, Y.; Deng, Y.; Wu, Y.; Cen, X.; Zhou, X.; Zhao, X.; Wang, Y.; Ji, Z.
10.1101/2023.12.10.571021 — bioinformatics — Posted on 2023-12-11
2890 stGCL: A versatile cross-modality fusion method based on multi-modal graph contrastive learning for spatial transcriptomics
Yu, N.; Zhang, D.; Zhang, W.; Liu, Z.; Qiao, X.; Wang, C.; Zhao, M.; Chao, B.; Li, W.; De Marinis, Y.; Gao, R.
10.1101/2023.12.10.571025 — bioinformatics — Posted on 2023-12-11
2892 Structural variation discovery in wheat using PacBio high-fidelity sequencing
Zhang, Z.; Zhang, J.; Kang, L.; Qiu, X.; Xu, S.; Xu, J.; Guo, Y.; Niu, Z.; Niu, B.; Bi, A.; Zhao, X.; Xu, D.; Wang, J.; Yin, C.; Lu, F.
10.1101/2023.12.08.570887 — genomics — Posted on 2023-12-11
2893 Exploring the embodied mind: functional connectome fingerprinting of meditation expertise
Czajko, S.; Zorn, J.; Perry, R.; Daumail, L.; Chetelat, G.; Margulies, D.; Lutz, A.
10.1101/2023.12.06.570128 — neuroscience — Posted on 2023-12-11
2898 Quantitative Dynamic Analysis of de novo Sphingolipid Biosynthesis in Arabidopsis thaliana
Osinuga, A.; Solis, A. G.; Cahoon, R. E.; Adil Al-Siyabi, A.; Cahoon, E. B.; Saha, R.
10.1101/2023.12.08.570827 — systems biology — Posted on 2023-12-10
2900 A Day in the Life of Arabidopsis: 24-Hour Time-lapse Single-nucleus Transcriptomics Reveal Cell-type specific Circadian Rhythms
Qin, Y.; Liu, Z.; Gao, S.; Long, Y.; Zhu, X.; Liu, B.; Gao, Y.; Xie, Q.; Nohales, M. A.; Xu, X.; Zhai, J.
10.1101/2023.12.09.570919 — plant biology — Posted on 2023-12-10
2907 Senescence phenotype of lymph node stromal cells from patients with rheumatoid arthritis is partly restored by dasatinib treatment
de Jong, T. A.; Semmelink, J. F.; Bolt, J. W.; Grasso, C.; Hoebe, R. A.; Krawczyk, P. M.; van Baarsen, L. G.
10.1101/2023.12.10.571042 — cell biology — Posted on 2023-12-11
2908 Nuclear cytoophidia assembly represses transcriptional activity to control skeletal development and homeostasis
Xu, C.; Wei, Z.; Lv, L.; Dong, X.; Xia, W.; Xing, J.; Liu, H.; Zhao, X.; Liu, Y.; Wang, W.; Jiang, H.; Gong, Y.; Liu, C.; Xu, K.; Wang, S.; Akimoto, Y.; Hu, Z.
10.1101/2023.12.10.571026 — cell biology — Posted on 2023-12-11
2911 Peribacillus frigoritolerans T7-IITJ, a potential biofertilizer, induces plant growth-promotinggenes of Arabidopsis thaliana
MARIK, D.; Sharma, P.; CHAUHAN, N. S.; Jangir, N.; Shekhawat, R. S.; Verma, D.; MUKHERJEE, M.; Abiala, M.; Roy, C.; YADAV, P.; SADHUKHAN, A.
10.1101/2023.12.09.570910 — plant biology — Posted on 2023-12-10
2912 A super-resolution compatible workflow for highly multiplexed immunofluorescence of routinely processed kidney tissue
Siegerist, F.; Kitzel, S.; Telli, N.; Dikou, J. S.; Drenic, V.; Chadjichristos, C. E.; Chatziantoniou, C.; Endlich, N.
10.1101/2023.12.11.570994 — cell biology — Posted on 2023-12-11
2913 Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer's disease
Sasmita, A. O.; Depp, C.; Nazarenko, T.; Sun, T.; Siems, S. B.; Yu, X.; Boehler, C.; Ong, E. C.; Bues, B.; Evangelista, L.; Morgado, B.; Wu, Z.; Ruhwedel, T.; Subramanian, S.; Boerensen, F.; Overhoff, K.; Spieth, L.; Berghoff, S. A.; Sadleir, K. R.; Vassar, R.; Eggert, S.; Goebbels, S.; Saito, T.; Saido, T.; Moebius, W.; Castelo-Branco, G.; Klafki, H.-W.; Wirths, O.; Wiltfang, J.; Jaekel, S.; Yan, R.; Nave, K.-A.
10.1101/2023.12.11.570514 — neuroscience — Posted on 2023-12-11
2915 Genotypic and resistance profile analysis of two oat crown rust differential sets urge coordination and standardisation
Nguyen, D. T.; Henningsen, E. C.; Lewis, D. C.; Mago, R.; McNeil, M.; Suchecki, R.; Boden, S.; Sperschneider, J.; Kianian, S.; Dodds, P. N.; Figueroa, M.
10.1101/2023.09.28.559455 — plant biology — Posted on 2023-12-11
2916 Maize mutants in miR394-regulated genes show improved drought tolerance
Miskevish, F.; Lodeyro, A. F.; Ponso, M. A.; Bouzo, C.; Meeley, R. B.; Timmermans, M. C.; Dotto, M. C.
10.1101/2023.12.05.570184 — plant biology — Posted on 2023-12-11
2918 A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
Mzoughi, S.; Schwarz, M.; Wang, X.; Demircioglu, D.; Ulukaya, G.; Mohammed, K.; Di Tullio, F.; Company, C.; Dramaretska, Y.; Leushacke, M.; Giotti, B.; Lannagan, T.; Lozano-Ojalvo, D.; Hasson, D.; Tsankov, A.; Sansom, O. J.; Marine, J.-C.; Barker, N.; Gargiulo, G.; Guccione, E.
10.1101/2023.12.10.570854 — cancer biology — Posted on 2023-12-10
2919 Uncovering Minimal Pathways in Melanoma Initiation
Xiao, H.; Shiu, J.; Chen, C.-F.; Wu, J.; Zhou, P.; Telang, S. S.; Ruiz-Vega, R.; Lander, A. D.; Ganesan, A. K.
10.1101/2023.12.08.570336 — cancer biology — Posted on 2023-12-10
2920 High-density sampling reveals volume growth in human tumours
Angaji, A.; Owusu, M.; Velling, C.; Dick, N.; Weghorn, D.; Berg, J.
10.1101/2023.12.10.570995 — cancer biology — Posted on 2023-12-10
2921 RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4
Weinstein, H. N. W.; Hu, K.; Fish, L.; Chen, Y.-A.; Allegakoen, P.; Hui, K. S. F.; Pham, J. H.; Baco, M. B.; Song, H.; Giacomelli, A. O.; Vazquez, F.; Ghandi, M.; Goodarzi, H.; Huang, F. W.
10.1101/2023.12.10.570873 — cancer biology — Posted on 2023-12-10
2922 SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma
Daley, B. R.; Sealover, N. E.; Sheffels, E.; Hughes, J. M.; Gerlach, D.; Hofmann, M. H.; Kostyroko, K.; Mair, B.; Linke, A.; Beckley, Z.; Frank, A.; Dalgard, C. L.; Kortum, R. L.
10.1101/2023.12.07.570642 — cancer biology — Posted on 2023-12-11
2923 A Fast Interferometric Beam Shaper for Multi-Emitter 3D MINFLUX
Geismann, M. K.; Gomez-Segalas, A.; Passera, A.; Shirzadian, M.; Balzarotti, F.
10.1101/2023.12.09.570565 — biophysics — Posted on 2023-12-10
2924 A pilot study of the comparison using a standard and individual altitude exposure protocol in elite gymnasts
Grushin, A.; Zelenkova, I.; Zotkin, S.; Ilin, D.; Korneev, P.; Koprov, S.; Almyashev, D.; Badtieva, V.; Glazachev, O.
10.1101/2023.12.08.569719 — physiology — Posted on 2023-12-10
2925 Protein-specific crowding accelerates aging in phase-separated droplets
Brzezinski, M.; Argudo, P. G.; Scheidt, T.; Yu, M.; Lemke, E. A.; Michels, J.; Parekh, S. H.
10.1101/2023.12.10.570970 — biophysics — Posted on 2023-12-10
2930 ATAT: Automated Tissue Alignment and Traversal in Spatial Transcriptomics with Self-Supervised Learning
Song, S.; Mohsin, E.; Zhang, R.; Kuznetsov, A.; Shen, L.; Grossman, R. L.; Weber, C. R.; Khan, A. A.
10.1101/2023.12.08.570839 — bioinformatics — Posted on 2023-12-10
2935 DSMBind: SE(3) denoising score matching for unsupervised binding energy prediction and nanobody design
Jin, W.; Chen, X.; Vetticaden, A.; Sarzikova, S.; Raychowdhury, R.; Uhler, C.; Hacohen, N.
10.1101/2023.12.10.570461 — bioinformatics — Posted on 2023-12-10
2937 Identification and characterization of specific motifs in effector proteins of plant parasites using MOnSTER.
Calia, G.; Porracciolo, P.; chen, Y.; Kozlowski, D.; Schuler, H.; Cestaro, A.; Quentin, M.; Favery, B.; Danchin, E. G. J.; Bottini, S.
10.1101/2023.07.03.547457 — bioinformatics — Posted on 2023-12-11
2939 ST-GEARS: Advancing 3D Downstream Research through Accurate Spatial Information Recovery
Xia, T.; Hu, L.; Zuo, L.; Zhang, Y.; Xu, M.; Lu, Q.; Zhang, L.; Cao, L.; Pan, T.; Zhang, B.; Ma, B.; Chen, C.; Guo, J.; Shi, C.; Li, M.; Liu, C.; Li, Y.; Zhang, Y.; Fang, S.
10.1101/2023.12.09.570320 — bioinformatics — Posted on 2023-12-11
2940 Unravelling the Mitochondrial Mutational Landscape in Chordates: damage-induced versus replication-induced signatures, their Etiologies, and dynamics
Iliushchenko, D.; Efimenko, B.; Mikhailova, A. G.; Shamanskiy, V.; Saparbaev, M.; Mazunin, I.; Knorre, D.; Kunz, W.; Denisov, S.; Khrapko, K.; Fellay, J.; Gunbin, K.; Popadin, K.
10.1101/2023.12.08.570826 — bioinformatics — Posted on 2023-12-11
2942 Highly efficient transgenic mouse production using piggyBac and its application to rapid phenotyping at the founder generation
Okamura, E.; Mizuno, S.; Matsumoto, S.; Murata, K.; Tanimoto, Y.; Tra, D. T. H.; Suzuki, H.; Kang, W.; Ema, T.; Morimoto, K.; Kato, K.; Matsumoto, T.; Masuyama, N.; Kijima, Y.; Morimura, T.; Sugiyama, F.; Takahashi, S.; Mizutani, E.; Woltjen, K.; Yachie, N.; Ema, M.
10.1101/2023.12.10.570953 — bioengineering — Posted on 2023-12-10
2943 Tissue stiffness mapping by light sheet elastography
Zhu, M.; Zhang, K.; Thomas, E. C.; Xu, R.; Ciruna, B.; Hopyan, S.; Sun, Y.
10.1101/2023.12.09.570896 — bioengineering — Posted on 2023-12-10
2944 Bioaugmentation strategies based on bacterial and methanogenic cultures to relieve stress in anaerobic digestion of protein-rich substrates
Agostini, S.; Bucci, L.; Doni, D.; Costantini, P.; Gupte, A.; Muller, B.; Sibilla, F.; Basaglia, M.; Casella, S.; Kougias, P. G.; Campanaro, S.; Favaro, L.; Treu, L.
10.1101/2023.12.11.571062 — bioengineering — Posted on 2023-12-11
2945 Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice
Hollingsworth, E. W.; Liu, T. A.; Jacinto, S. H.; Chen, C. X.; Alcantara, J. A.; Kvon, E. Z.
10.1101/2023.12.10.570890 — genomics — Posted on 2023-12-10
2946 Toward Best Practice in Identifying Subtle Differential Expression with RNA-seq: A Real-World Multi-Center Benchmarking Study Using Quartet and MAQC Reference Materials
Wang, D.; Liu, Y.; Zhang, Y.; Chen, Q.; Han, Y.; Hou, W.; Liu, C.; Yu, Y.; Li, Z.; Li, Z.; Zhao, J.; Zheng, Y.; Shi, L.; Li, J.; Zhang, R.
10.1101/2023.12.09.570956 — genomics — Posted on 2023-12-10
2948 Comparative transcriptomics provides insight into molecular mechanisms of zinc tolerance in the ectomycorrhizal fungus Suillus luteus
Smith, A.; Swinnen, J.; Jinckheere, K.; Bazzicalupo, A.; Liao, H.-L.; Ragland, G.; Colpaert, J.; Lipzen, A.; Tejomurthula, S.; Barry, K. W.; Grigoriev, I.; Ruytinx, J. V.; Branco, S.
10.1101/2023.12.08.570832 — genomics — Posted on 2023-12-10
2949 Longitudinal profiling of the pregnancy plasma proteome through organic solvent precipitation and nano LC-MS/MS
George, A. L.; Cook, E.; Smith, G. C. S.; Charnock-Jones, S. D.; O'Rahilly, S.; Reimann, F.; Gribble, F. M.; Kay, R. G.
10.1101/2023.12.11.571058 — biochemistry — Posted on 2023-12-11
2951 Sequence reliance of a Drosophila context-dependent transcription factor
Hodkinson, L. J.; Gross, J.; Schmidt, C. A.; Diaz-Saldana, P. P.; Aoki, T.; Rieder, L. E.
10.1101/2023.12.07.570650 — genetics — Posted on 2023-12-11
2957 Expression Patterns of Mal genes and its Association with Differential Maltose and Maltotriose Transport rate of Two Saccharomyces pastorianus Yeasts
Hernandez Vasquez, C. I.; Garcia Garcia, J. H.; Perez Ortega, E. d. R.; Damas Buenrostro, L. C.; Martinez Segundo, A. G.; Pereyra Alferez, B.
10.1101/2023.12.06.570446 — molecular biology — Posted on 2023-12-11
2958 Intercontinental panmixia despite distinct migration distances in the trans-Saharan butterfly migrant Vanessa cardui
Reich, M. S.; Shipilina, D.; Talla, V.; Bahleman, F.; Kebe, K.; Berger, J. L.; Backström, N.; Talavera, G.; Bataille, C. P.
10.1101/2023.12.10.569105 — evolutionary biology — Posted on 2023-12-10
2959 TML1 AND TML2 SYNERGISTICALLY REGULATE NODULATION BUT NOT ARBUSCULAR MYCORRHIZA IN MEDICAGO TRUNCATULA
Chaulagain, D.; Schnabel, E.; Lin, E. X.; Garcia, R. R.; Noorai, R. E.; Müller, L. M.; Frugoli, J. A.
10.1101/2023.12.07.570674 — molecular biology — Posted on 2023-12-11
2961 The two key substitutions in the chromophore environment of mKate2 to produce an enhanced FusionRed-like red fluorescent protein
Ruchkin, D. A.; Gavrikov, A. S.; Kolesov, D. V.; Gorokhovatsky, A. Y.; Chepurnykh, T. V.; Mishin, A. S.; Maximov, E. G.; Pletneva, N. V.; Pletnev, V. Z.; Lukyanov, K. A.; Bogdanov, A. M.
10.1101/2023.12.05.570295 — molecular biology — Posted on 2023-12-11
2962 Coevolution with toxic prey produces functional trade-offs in sodium channels of predatory snakes
del Carlo, R. E.; Reimche, J. S.; Moniz, H. A.; Hague, M. T. J.; Agarwal, S. R.; Brodie, E. D.; Brodie, E. D.; Leblanc, N.; Feldman, C. R.
10.1101/2023.12.08.570760 — evolutionary biology — Posted on 2023-12-11
2963 Unraveling the Molecular Complexity of Bicuspid Aortopathy: Lessons from Comparative Proteomics
Pozo-Vilumbrales, B.; Martin-Chaves, L.; Lopez-Unzu, M. A.; Soto-Navarrete, M. T.; Pavon-Moron, F. J.; Rodriguez-Capitan, J.; Fernandez, B.
10.1101/2023.12.05.570304 — molecular biology — Posted on 2023-12-11
2965 FOXA2 is essential for maintaining the urea cycle in acute liver failure
Feng, R.; Liu, R.; Tong, C.; Lin, T.; Li, X.; Liu, H.; Shao, C.; Kan, K.; Sticht, C.; Li, Y.; Wang, S.; Munker, S.; Wirth, U.; Niess, H.; Liebe, R.; Meyer, C.; Wang, S.; Ebert, M. P.; Dooley, S.; Ding, H.; Wang, H.; Weng, H.
10.1101/2023.12.11.570955 — molecular biology — Posted on 2023-12-11
2966 Microbial metabolic specificity controls pelagic lipid export efficiency
Behrendt, L.; Alcolombri, U.; Hunter, J. E.; Smriga, S.; Mincer, T.; Lowenstein, D. P.; Yawata, Y.; Peaudecerf, F.; Fernandez, V.; Fredricks, H. F.; Almblad, H.; Harrison, J. J.; Stocker, R.; Van Mooy, B. A. S.
10.1101/2023.12.08.570822 — ecology — Posted on 2023-12-10
2967 The gut commensal Blautia maintains colonic mucus function under low fiber consumption through short-chain fatty acid-mediated activation of Ffar2
Holmberg, S. M.; Feeney, R. H.; Prasoodanan P.K., V.; Puertolas-Balint, F.; Singh, D. K.; Wongkuna, S.; Zandbergen, L. M.; Hauner, H.; Brandl, B.; Nieminen, A. I.; Skurk, T.; Schroeder, B. O.
10.1101/2023.12.10.570766 — microbiology — Posted on 2023-12-10
2968 Quantitative description of six fish species' gut contents and abundances of their prey in the benthic food web of the Baltic Sea (1968-1978)
Gauzens, B.; Kalinkat, G.; O'Gorman, E.; Antunes, A. C.; Boy, T.; Jacob, U.; Jochum, M.; Kortsch, S.; Rosenbaum, B.; Figueiredo, L.; Brose, U.
10.1101/2023.12.08.570787 — ecology — Posted on 2023-12-10
2969 Exploring the prokaryote-eukaryote interplay in microbial mats from an Andean athalassohaline wetland
Lopez-Garcia, P.; Cubillos, C. F.; Aguilar, P.; Moreira, D.; Bertolino, P.; Iniesto, M.; Dorador, C.
10.1101/2023.12.05.570274 — microbiology — Posted on 2023-12-10
2972 Umbrella toxin particles produced by Streptomyces block mycelial growth of competing species
Zhao, Q.; Bertolli, S.; Park, Y.-J.; Tan, Y.; Cutler, K. J.; Srinivas, P.; Asfahl, K. L.; Fonseca Garcia, C.; Gallagher, L. A.; Li, Y.; Wang, Y.; Coleman-Derr, D.; DiMaio, F.; Zhang, D.; Peterson, S. B.; Veesler, D.; Mougous, J. D.
10.1101/2023.12.09.570830 — microbiology — Posted on 2023-12-10
2974 Bacterial pathogens dynamic during multi-species infections
Barny, M.-A.; Thieffry, S.; Gomes de Faria, C.; Thebault, E.; Pedron, J.
10.1101/2023.12.06.570389 — microbiology — Posted on 2023-12-11
2976 A niche-adapted brain microbiome in salmonids at homeostasis
Mani, A.; Henn, C.; Couch, C.; Patel, S.; Korytar, T.; Salinas, I.
10.1101/2023.12.07.570641 — microbiology — Posted on 2023-12-11
2977 Zika virus remodels and hijacks IGF2BP2 ribonucleoprotein complex to promote viral replication organelle biogenesis
Mazeaud, C.; Pfister, S.; Owen, J. E.; Pereira, H. S.; Robinson, Z. E.; Anton, A.; Bemis, C. L.; Sow, A. A.; Patel, T. R.; Neufeldt, C. J.; Scaturro, P.; Chatel-Chaix, L.
10.1101/2023.12.08.570783 — microbiology — Posted on 2023-12-11
2979 Alka(e)nes contribute to membrane lipid homeostasis and resilience of photosynthesis to high light in cyanobacteria
Miao, R.; Legeret, B.; Cuine, S.; Burlacot, A.; Lindblad, P.; Li-Beisson, Y.; Beisson, F.; Peltier, G.
10.1101/2023.12.11.571064 — microbiology — Posted on 2023-12-11
2980 Integrated omics analysis unveils a DNA damage response to neurogenic injury
Hashemi Gheinani, A.; Sack, B. S.; Bigger-Allen, A.; Thaker, H.; Atta, H.; Lambrinos, G.; Costa, K.; Doyle, C.; Gharaee-Kermani, M.; Patalano, S.; Piper, M.; Cotellessa, J. F.; Vitko, D.; Li, H.; Kadayil Prabhakaran, M.; Cristofaro, V.; Froehlich, J.; Lee, R. S.; Yang, W.; Sullivan, M. P.; Macoska, J. A.; Adam, R. M.
10.1101/2023.12.10.571015 — cell biology — Posted on 2023-12-10
2981 Molecular Determinants and Signaling Effects of PKA RIα Phase Separation
Hardy, J. C.; Pool, E. H.; Bruystens, J. G. H.; Zhou, X.; Li, Q.; Zhou, D. R.; Palay, M.; Tan, G.; Chen, L.; Choi, J. L. C.; Lee, H. N.; Strack, S.; Wang, D.; Taylor, S. S.; Mehta, S.; Zhang, J.
10.1101/2023.12.10.570836 — cell biology — Posted on 2023-12-11
2982 E3 ligase ASB3 downregulates antiviral innate immunity by targeting MAVS for ubiquitin-proteasomal degradation
Cheng, M.; Lu, Y.; Wang, J.; Wang, H.; Sun, Y.; Zhao, W.; Wang, J.; Shi, C.; Luo, J.; Gao, M.; Yu, T.; Wang, J.; Guan, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Cao, X.; Yang, D.; Wang, C.; Zeng, Y.
10.1101/2023.12.10.570965 — immunology — Posted on 2023-12-10
2983 Switching circuits: Modulating NK cell response to TGF-β using novel receptors
Turk, R.; Guo, L.; Belmont, B. J.; Bogard, N.; Chen, A. T.; Williams, M. D.; Young, M.; Stone, M. R.; Daines, B.; Darnell, M.
10.1101/2023.12.10.570687 — immunology — Posted on 2023-12-10
2985 Dendritic cell-derived lncRNA in patients with acute coronary syndrome
Wang, Z.; Ke, C.; Cheng, Y.; Zhao, Y.; He, Y.; Liang, X.; Tu, Q.; Min, X.; Guo, f.; Ge, J.; Shi, B.
10.1101/2023.12.05.570310 — immunology — Posted on 2023-12-11
2986 Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.
Nair-Gill, E.; Russell, J.; Chen, L.; Liu, A.; Wang, J.; Ghosh, S.; Zhong, X.; Shi, H.; Beutler, B.
10.1101/2023.12.08.570738 — immunology — Posted on 2023-12-11
2987 Flotillins affect LPS-induced TLR4 signaling by modulating the trafficking and abundance of CD14
Matveichuk, O. V.; Ciesielska, A.; Hromada-Judycka, A.; Nowak, N.; Ben Amor, I.; Kwiatkowska, K.
10.1101/2023.12.11.571077 — immunology — Posted on 2023-12-11
2990 Injectable 3D microcultures enable intracerebral transplantation of mature neurons directly reprogrammed from patient fibroblasts
Kajtez, J.; Nilsson, F.; Laurin, K.; Bruzelius, A.; Cepeda-Prado, E.; Birtele, M.; Barker, R. A.; Herborg, F.; Ottosson, D. R.; Storm, P.; Fiorenzano, A.; Habekost, M.; Parmar, M.
10.1101/2023.12.10.570992 — neuroscience — Posted on 2023-12-10
2992 A Pose-Informed De-Noising Diffusion Model for Adult Naturalistic EEG Signals
Dutta, A.; Hirt, M.; Santamaria, L.; Georgieva, S.; Gerloff, C.; Li, B.; Leong, V.
10.1101/2023.12.08.567146 — neuroscience — Posted on 2023-12-10
2994 Lifestyle and brain health determinants of word-finding failures in healthy ageing
Rahman, F.; Tsvetanov, K. A.; Feron, J.; Mullinger, K.; Joyce, K.; Gilani, A.; Fernandes, E. G.; Wetterlin, A.; Wheeldon, L. R.; Lucas, S. J. E.; Segaert, K.
10.1101/2023.12.08.570799 — neuroscience — Posted on 2023-12-10
2996 Serotonin Reduces Belief Stickiness
Conceicao, V. A.; Petzschner, F. H.; Cole, D. M.; Wellstein, K. V.; Müller, D.; Raman, S.; Maia, T. V.
10.1101/2023.12.08.570769 — neuroscience — Posted on 2023-12-10
2998 Evolutionary and Developmental Specialization of Foveal Cell Types in the Marmoset
Zhang, L.; Cavallini, M.; Wang, J.; Xin, R.; Zhang, Q.; Feng, G.; Sanes, J. R.; Peng, Y.-R.
10.1101/2023.12.10.570996 — neuroscience — Posted on 2023-12-10
2999 Uncovering network mechanism underlying thalamic Deep Brain Stimulation using a novel firing rate model
Tian, Y.; Bello, E.; Crompton, D.; Kalia, S.; Hodaie, M.; Lozano, A. M.; Hutchison, W. D.; Johnson, M.; Popovic, M. R.; Milosevic, L.; Lankarany, M.
10.1101/2023.12.09.570924 — neuroscience — Posted on 2023-12-10
3000 Tuning of cortical color mechanism revealed using steady-state visually evoked potentials
Watts, D. J.; Rozman, A.; Somers, L. P.; Günel, B.; Racey, C.; Barnes, K. L.; Bosten, J. M.
10.1101/2023.12.10.570997 — neuroscience — Posted on 2023-12-10
3001 Functional Connectivity, Tissue Microstructure And T2 At 11.1 Tesla Distinguishes Neuroadaptive Differences In Two Contusive Brain Injury Models In Rats
Kommireddy, R. S.; Mehra, S.; Pompilus, M.; Arja, R. D.; Zhu, T.; Yang, Z.; Fu, Y.; Zhu, J.; Kobeissy, F.; Wang, K. K. W.; Febo, M.
10.1101/2023.12.10.570975 — neuroscience — Posted on 2023-12-10
3002 Atenolol reduces cardiac-mediated mortality in a genetic mouse model of sudden unexpected death in epilepsy
Soh, M. S.; Kuanyshbek, A.; Mohamed Syazwan, E. S.; Lee, H. M.; McKenzie, C. E.; Phillips, A. M.; Hu, A.; Scheffer, I. E.; Semsarian, C.; Berkovic, S. F.; Reid, C. A.
10.1101/2023.12.10.570964 — neuroscience — Posted on 2023-12-10
3006 Direct disassembly of alpha-syn preformed fibrils into native alpha-syn monomers by an all-D-peptide
Sevenich, M.; Gering, I.; Vollmer, M.; Aghabashlou Saisan, S.; Tusche, M.; Kupreichyk, T.; Pauly, T.; Stoldt, M.; Hoyer, W.; Willuweit, A.; Kutzsche, J.; Lakomek, N.-A.; Nagel-Steger, L.; Gremer, L.; Tamgueney, G.; Mohrlueder, J.; Willbold, D.
10.1101/2023.12.11.571053 — neuroscience — Posted on 2023-12-11
3007 Bone quality following peripubertal growth in a mouse model of transmasculine gender-affirming hormone therapy
Henry, B.; Dela Cruz, C.; Goulet, R. W.; Nolan, B. T.; Locke, C.; Padmanabhan, V.; Moravec, M.; Shikanov, A.; Killian, M. L.
10.1101/2023.12.08.570840 — physiology — Posted on 2023-12-10
3009 Rapid long-distance migration of RPA on single stranded DNA occurs through intersegmental transfer utilizing multivalent interactions
Pangeni, S.; Biswas, G.; Kaushik, V.; Kuppa, S.; Yang, O.; Lin, C.-T.; Mishra, G.; Levy, Y.; Antony, E.; Ha, T.
10.1101/2023.12.09.570606 — biophysics — Posted on 2023-12-10
3011 Early Embryonic Establishment of Constitutive Heterochromatin Involves H3K14ac-mediated Recruitment of Eggless/SetDB1
Tang, R.; Zhou, M.; Chen, Y.; Jiang, Z.; Fan, X.; Zhang, J.; Dong, A.; Lv, L.; Mao, S.; Chen, F.; Min, J.; Liu, K.; Yuan, K.
10.1101/2023.12.10.570967 — developmental biology — Posted on 2023-12-10
3012 Nucleolar Pol II interactome reveals TBPL1, PAF1, and Pol I at intergenic rDNA drive rRNA biogenesis
Khosraviani, N.; Yerlici, V. T.; St-Germain, J.; Hou, Y. Y.; Cao, S. B.; Ghali, C.; Krishnan, R.; Hakem, R.; Raught, B.; Mekhail, K.
10.1101/2023.12.10.570972 — molecular biology — Posted on 2023-12-10
3013 An isogenic E. coli population gives rise to multiple persister phenotypes
Rahman, K. M. T.; Amaratunga, R.; Singh, A.; Hossain, T.; Butzin, N. C.
10.1101/2023.12.09.570944 — microbiology — Posted on 2023-12-10
3015 The Salmon Microbial Genome Atlas enables novel insights into bacteria-host interactions via functional mapping
de Leon, A. V.-P.; Hoetzinger, M.; Hensen, T.; Gupta, S.; Weston, B.; Johnsen, S. M.; Rasmussen, J. A.; Clausen, C. G.; Pless, L.; Verissimo, A. R. A.; Rudi, K.; Snipen, L. G.; Karlsen, C. R.; Limborg, M. T.; Bertilsson, S.; Thiele, I.; Hvidsten, T. R.; Sandve, S. R.; Pope, P. B.; La Rosa, S. L.
10.1101/2023.12.10.570985 — microbiology — Posted on 2023-12-10
3017 The Legionella collagen-like protein employs a unique binding mechanism for the recognition of host glycosaminoglycans
Rehman, S.; Antonovic, A.; McIntire, I.; Zheng, H.; Cleaver, L.; Adams, C.; Portlock, T.; Richardson, K.; Shaw, R.; Oregioni, A.; Mastroianni, G.; Whittaker, S.; Kelly, G.; Fornili, A.; Cianciotto, N.; Garnett, J.
10.1101/2023.12.10.570962 — microbiology — Posted on 2023-12-10
3018 Apramycin efficacy in the treatment of carbapenem-resistant Enterobacterales in murine blood stream infection models
Frimodt-Moller, N.; Hansen, J. U.; Plattner, M.; Huseby, D.; Almind, S. R.; Haldimann, K.; Gysin, M.; Petersson, A.; Ercan, O.; Ganz, L.; Hughes, D.; Lundberg, C. V.; Hobbie, S.
10.1101/2023.12.10.570991 — microbiology — Posted on 2023-12-10
3019 Intestinal epithelial Atg16l1 influences pregnancy-induced fecal microbiota shifts in mice
Lopez-Agudelo, V. A.; Falk-Paulsen, M.; Rehman, A.; Bharti, R.; Sommer, F.; Wacker, E. M.; Ellinghaus, D.; Luzius, A.; Sievers, L. K.; Kaser, A.; Rosenstiel, P.
10.1101/2023.12.10.570427 — microbiology — Posted on 2023-12-10
3020 Complement-mediated killing of bacteria by mechanical destabilization of the cell envelope
Benn, G.; Bortolini, C.; Roberts, D. M.; Pyne, A. L. B.; Holden, S.; Hoogenboom, B. W.
10.1101/2023.12.10.570986 — microbiology — Posted on 2023-12-10
3022 SIRPα controls CD47-dependent platelet clearance in mice and humans
Shoham, M.; Yiu, Y. Y.; Hansen, P.; Subramaniam, A.; Broberg, M.; Gars, E.; Raveh, T.; FinnGen, ; Weissman, I. L.; Sinnott-Armstrong, N.; Krishnan, A.; Ollila, H.; Tal, M. C.
10.1101/2023.12.09.570874 — immunology — Posted on 2023-12-10
3024 Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A
Brierley, C. K.; Yip, B. H.; Orlando, G.; Goyal, H.; Wen, S.; Wen, J.; Levine, M. F.; Jakobsdottir, M. G.; Rodriguez-Meira, A.; Adamo, A.; Bashton, M.; Hamblin, A.; Clark, S. A.; O'Sullivan, J.; Murphi, L.; Olijnik-French, A.-A.; Cotton, A.; Narina, S.; Pruett-Miller, S.; Enshaei, A.; Harrison, C.; Drummond, M.; Knapper, S.; Tefferi, A.; Antony-Debre, I.; Thongjuea, S.; Wedge, D. C.; Constantinescu, S.; Papaemmanuil, E.; Psaila, B.; Crispino, J. D.; Mead, A. J.
10.1101/2023.12.08.570880 — cancer biology — Posted on 2023-12-10
3027 Structure basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor
Jin, S.; Li, X.; Xu, Y.; Guo, S.; Wu, C.; Pan, B.; Xin, W.; Zhang, H.; Hu, W.; Yin, Y.; Zhang, T.; Wu, K.; Yuan, Q.; Xu, H. E.; Xie, X.; Jiang, Y.
10.1101/2023.12.09.570933 — biophysics — Posted on 2023-12-10
3028 Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology
Maharjan, S.; Gamper, H.; Yamaki, Y.; Henley, R. Y.; Sheng, N.; Suzuki, T.; Suzuki, T.; Piccirilli, J. A.; Wanunu, M.; Seifert, E.; Wallace, D. C.; Hou, Y.-M.
10.1101/2023.12.09.569632 — cell biology — Posted on 2023-12-10
3030 Regulation of the circadian clock in C. elegans by clock gene homologs kin-20 and lin-42
Lamberti, M. L.; Spangler, R. K.; Cerdeira, V.; Ares, M.; Rivollet, L.; Ashley, G. E.; Coronado, A. R.; Tripathi, S.; Spiousas, I.; Ward, J. D.; Partch, C. L.; Benard, C. Y.; Goya, M. E.; Golombek, D. A.
10.1101/2023.04.13.536481 — neuroscience — Posted on 2023-12-10
3032 Profiling the proximal proteome of the mu opioid receptor identifies novel regulators of receptor signaling and trafficking
Polacco, B. J.; Lobingier, B. T.; Blythe, E. E.; Abreu, N.; Khare, P.; Howard, M. K.; Gonzalez-Hernandez, A. J.; Xu, J.; Li, Q.; Novy, B.; Naing, Z. Z. C.; Shoichet, B. K.; Coyote-Maestas, W.; Levitz, J.; Krogan, N. J.; Von Zastrow, M.; Huttenhain, R.
10.1101/2022.03.28.486115 — systems biology — Posted on 2023-12-10
3033 PINK1 and BNIP3 mitophagy inducers have an antagonistic effect on Rbf1-induced apoptosis in Drosophila.
FAGES, M.; RUBY, V.; BRUSSON, M.; RINCHEVAL-ARNOLD, A.; WINTZ, C.; BOULEAU, S.; GUENAL, I.
10.1101/2023.12.10.568976 — cell biology — Posted on 2023-12-10
3034 A novel nested gene Aff3ir participates in vascular remodelling by enhancing endothelial cell differentiation in mice
Zhao, Y.; Ehteramyan, M.; Li, Y.; Bai, X.; Huang, L.; Gao, Y.; Angbohang, A.; Yang, X.; Lynham, S.; Margariti, A.; Shah, A.; Tao, Y.; Cai, T.; Li, T.; Zhang, M.; Zeng, L.
10.1101/2023.12.09.570916 — cell biology — Posted on 2023-12-10
3035 Torques within and outside the human spindle balance twist at anaphase
Neahring, L.; He, Y.; Cho, N. H.; Liu, G.; Fernandes, J.; Rux, C. J.; Nakos, K.; Subramanian, R.; Upadhyayula, S.; Yildiz, A.; Dumont, S.
10.1101/2023.12.10.570990 — cell biology — Posted on 2023-12-10
3037 Adaptive epigenetic regulation of neuronal metabolism by a mitochondrial redox signal
Baeken, M. W.; Koetzner, P.; Richly, H.; Behl, C.; Moosmann, B.; Hajieva, P.
10.1101/2023.12.10.570533 — cell biology — Posted on 2023-12-10
3040 Astrocytes regulate neuronal network burst frequency through NMDA receptors species- anddonor-specifically
Rasanen, N.; Tiihonen, J.; Koskuvi, M.; Lehtonen, S.; Jalkanen, N.; Karmila, N.; Weert, I.; Vaurio, O.; Ojansuu, I.; Lahteenvuo, M.; Pietilainen, O.; Koistinaho, J.
10.1101/2023.12.09.570906 — neuroscience — Posted on 2023-12-10
3041 Dynamics of Adult Axin2 Cell Lineage Integration in Granule Neurons of the Dentate Gyrus
Sharifi, K. A.; Farzad, F.; Soldozy, S.; Price, R. J.; Kalani, M. Y. S.; Tvrdik, P.
10.1101/2023.12.09.570930 — neuroscience — Posted on 2023-12-10
3042 Estrogenic control of reward prediction errors and reinforcement learning
Golden, C. E. M.; Kaur, D.; Mah, A.; Martin, A. C.; Levy, D. H.; Yamaguchi, T.; Lin, D.; Aoki, C.; Constantinople, C. M.
10.1101/2023.12.09.570945 — neuroscience — Posted on 2023-12-10
3043 Brain encoding of naturalistic, continuous, and unpredictable tactile events
Castellani, N.; Federici, A.; Fantoni, M.; Ricciardi, E.; Garbarini, F.; Bottari, D.
10.1101/2023.12.08.570756 — neuroscience — Posted on 2023-12-10
3044 Biolearn, an open-source library for biomarkers of aging
Ying, K.; Paulson, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.
10.1101/2023.12.02.569722 — bioinformatics — Posted on 2023-12-10
3045 Liquid-liquid interfaces enable tunable cell confinement to recapitulate surrounding tissue deformations during neutrophil interstitial migration in vivo
Schrope, J. H.; Horn, A.; Farooqui, M.; Lazorchak, K.; Li, J.; Tinnen, C. W.; Stevens, J. J.; Bennin, D.; Robertson, T.; Juang, T. D.; Li, C.; Huttenlocher, A.; Beebe, D.
10.1101/2023.06.14.544898 — bioengineering — Posted on 2023-12-09
3046 Causality-Enriched Epigenetic Age Uncouples Damage and Adaptation
Ying, K.; Liu, H.; Tarkhov, A. E.; Sadler, M. C.; Lu, A. T.; Moqri, M.; Horvath, S.; Kutalik, Z.; Shen, X.; Gladyshev, V. N.
10.1101/2022.10.07.511382 — genetics — Posted on 2023-12-10
3047 Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in northeast Thailand
Seng, R.; Chomkatekaew, C.; Tandhavanant, S.; Saiprom, N.; Phunpang, R.; Thaipadungpanit, J.; Batty, E. M.; Day, N. P.; Chantratita, W.; West, T. E.; Thomson, N. R.; Parkhill, J.; Chewapreecha, C.; Chantratita, N.
10.1101/2023.06.02.543359 — microbiology — Posted on 2023-12-10
3049 Brain-wide topographic coordination of traveling spiral waves
Ye, Z.; Bull, M. S.; Li, A.; Birman, D.; Daigle, T. L.; Tasic, B.; Zeng, H.; Steinmetz, N. A.
10.1101/2023.12.07.570517 — neuroscience — Posted on 2023-12-09
3051 Application of slow-controlled release fertilizer coordinates the carbon flow in carbon-nitrogen metabolism to effect rice quality
Jiang, Z.; Chen, Q.; Liu, D.; Tao, W.; Gao, S.; Li, J.; Lin, C.; Zhu, M.; Ding, Y.; Li, W.; Li, G.; Sakr, S.; Xue, L.
10.1101/2023.12.07.570515 — plant biology — Posted on 2023-12-09
3052 Challenges and advances in measuring phenotypic convergence
Grossnickle, D. M.; Brightly, W. H.; Weaver, L. N.; Stanchak, K. E.; Roston, R. A.; Pevsner, S. K.; Stayton, C. T.; Polly, P. D.; Law, C. J.
10.1101/2022.10.18.512739 — evolutionary biology — Posted on 2023-12-09
3053 Oligonucleotide-based CRISPR-Cas9 toolbox for efficient engineering of Komagataella phaffii
Strucko, T.; Gadar-Lopez, A. E.; Frohling, F. B.; Frost, E. T.; Olsson, H.; Jarczynska, Z. D.; Mortensen, U. H.
10.1101/2023.12.09.570913 — synthetic biology — Posted on 2023-12-09
3054 Structural insights into specific recognition of PTENα/β-NTE by WDR5 in cancer progression
Huang, X.; Zhang, C.; Shang, X.; Chen, Y.; Xiao, Q.; Wei, Z.; Wang, G.; Zhen, X.; Xu, G.; Min, J.; Shen, S.; Liu, Y.
10.1101/2023.12.09.570908 — cancer biology — Posted on 2023-12-09
3055 Collective directional memory controls the range of epithelial cell migration
Canever, H.; Lachuer, H.; Delaunay, Q.; Sipieter, F.; Auduge, N.; Borghi, N.
10.1101/2023.12.08.570811 — biophysics — Posted on 2023-12-09
3058 uniLIVER: a Human Liver Cell Atlas for Data-Driven Cellular State Mapping
Wu, Y.; Fan, Y.; Miao, Y.; Li, Y.; Chen, Z.; Du, G.; Diao, J.; Chen, Y.-A.; Ye, M.; You, R.; Chen, A.; Chen, Y.; Li, W.; Guo, W.; Dong, J.; Zhang, X.; Wang, Y.; Gu, J.
10.1101/2023.12.09.570903 — bioinformatics — Posted on 2023-12-09
3060 Genome-Wide Profiling of tRNA Using an Unexplored Reverse Transcriptase with High Processivity
Nakano, Y.; Gamper, H.; McGuigan, H.; Maharjan, S.; Sun, Z.; Krishnan, K.; Yigit, E.; Li, N.-S.; Piccirilli, J. A.; Kleiner, R. E.; Nichols, N.; Hou, Y.-M.
10.1101/2023.12.09.569604 — genomics — Posted on 2023-12-09
3061 Disease-decreasing diversity: evidence for lowered parasite prevalence in microscopic nematode communities with higher species numbers
van Himbeeck, R.; Sowa, J. N.; Tamim El Jarkass, H.; Wu, W.; Oude Vrielink, J.; Riksen, J. A. G.; Reinke, A.; van Sluijs, L.
10.1101/2023.12.08.570776 — ecology — Posted on 2023-12-09
3063 Effects of urbanisation, habitat characteristics, and management on garden pond biodiversity: a citizen science approach
Marton, Z.; Barta, B.; Vad, C. F.; Szabo, B.; Hamer, A. J.; Kardos, V.; Laskai, C.; Fierpasz, A.; Horvath, Z.
10.1101/2023.12.08.570789 — ecology — Posted on 2023-12-09
3066 WRN Inhibition Leads to its Chromatin-Associated Degradation Via the PIAS4-RNF4-p97/VCP Axis
Rodriguez Perez, F.; Natwick, D. E.; Schiff, L.; Huey, M.; McSwiggen, D.; Heckert, A.; Ortega, J.; Loo, M.; Miranda, R.; Morrison, H. M.; Butler, R.; Cheng, K.; Filbin, J.; Gonzalez, E.; Rand, M.; Tang, Y.; Ho, J. J.; Zhang, Z.; Anderson, D. J.; Bashore, C.; Basham, S.
10.1101/2023.12.08.570895 — molecular biology — Posted on 2023-12-09
3067 Lactiplantibacillus plantarum K8 lysates regulate hypoxia-induced gene expression
Jeong, J.; Kang, B.-H.; Ju, S.; Park, N. Y.; Kim, D.; Dinh, N. T. B.; Lee, J.; Rhee, C. Y.; Cho, D.-H.; Kim, H.; Chung, D. K.; Bunch, H.
10.1101/2023.12.08.570897 — molecular biology — Posted on 2023-12-09
3071 Skin microbiota variation in Indian families
Potbhare, R.; RaviKumar, A.; Munukka, E.; Ashma, R.; Lahti, L.
10.1101/2023.12.09.570904 — microbiology — Posted on 2023-12-09
3072 High-resolution awake mouse fMRI at 14 Tesla
Hike, D.; Liu, X.; Xie, Z.; Zhang, B.; Choi, S.; Zhou, X. A.; Liu, A.; Murstein, A.; Jiang, Y.; Devor, A.; Yu, X.
10.1101/2023.12.08.570803 — neuroscience — Posted on 2023-12-09
3073 Antagonistic effects of arginine methylation of LSM4 on alternative splicing during plant stress responses
Agrofoglio, Y. C.; Iglesias, M. J.; Perez-Santangelo, S.; de Leone, M. J.; Koester, T.; Catala, R.; Salinas, J.; Yanovsky, M. J.; Staiger, D.; Mateos, J. L.
10.1101/2023.12.08.570794 — plant biology — Posted on 2023-12-09
3076 Cortical tracking of postural sways during standing balance.
Legrand, T.; Mongold, S. J.; Muller, L.; Naeije, G.; Vander Ghinst, M.; Bourguignon, M.
10.1101/2023.12.08.570752 — neuroscience — Posted on 2023-12-09
3077 Virological characteristics of the SARS-CoV-2 JN.1 variant
Kaku, Y.; Okumura, K.; Padilla-Blanco, M.; Kosugi, Y.; Uriu, K.; Hinay, A. A.; Chen, L.; Plianchaisuk, A.; Kobiyama, K.; Ishii, K. J.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Zahradnik, J.; Ito, J.; Sato, K.
10.1101/2023.12.08.570782 — microbiology — Posted on 2023-12-09
3080 Somatic mutation as an explanation for epigenetic aging
Koch, Z.; Li, A. Y.; Evans, D.; Cummings, S.; Ideker, T.
10.1101/2023.12.08.569638 — genomics — Posted on 2023-12-09
3081 Strengthening Bordetella pertussis genomic surveillance by direct sequencing of residual positive specimens
Peng, Y.; Williams, M. M.; Xiaoli, L.; Simon, A. K.; Fueston, H.; Tondella, M. L.; Weigand, M. R.
10.1101/2023.12.08.570824 — genomics — Posted on 2023-12-09
3085 Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure
Girard-Tercieux, C.; Vieilledent, G.; Clark, A. T.; Clark, J. S.; Courbaud, B.; Fortunel, C.; Kunstler, G.; Pelissier, R.; Rueger, N.; Marechaux, I.
10.1101/2022.08.06.503032 — ecology — Posted on 2023-12-09
3088 In vitro validated antibody design against multiple therapeutic antigens using generative inverse folding
Shanehsazzadeh, A.; Alverio, J.; Kasun, G.; Levine, S.; Khan, J. A.; Chung, C.; Diaz, N.; Luton, B. K.; Tarter, Y.; McCloskey, C.; Bateman, K. B.; Carter, H.; Chapman, D.; Consbruck, R.; Jaeger, A.; Kohnert, C.; Kopec-Belliveau, G.; Sutton, J. M.; Guo, Z.; Canales, G.; Ejan, K.; Marsh, E.; Ruelos, A.; Ripley, R.; Stoddard, B.; Caguiat, R.; Chapman, K.; Saunders, M.; Sharp, J.; Ganini da Silva, D.; Feltner, A.; Ripley, J.; Bryant, M. E.; Castillo, D.; Meier, J.; Stegmann, C. M.; Moran, K.; Lemke, C.; Abdulhaqq, S.; Klug, L. R.; Bachas, S.
10.1101/2023.12.08.570889 — synthetic biology — Posted on 2023-12-09
3089 Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia
Iacobucci, I.; Zeng, A. G. X.; Gao, Q.; Garcia-Prat, L.; Baviskar, P.; Shah, S.; Murison, A. J.; Voisin, V.; Chan-Seng-Yue, M.; Cheng, C.; Qu, C.; Bailey, C.; Lear, M.; Witkowski, M.; Zhou, X.; Zaldivar Peraza, A.; Gangwani, K.; Advani, A.; Luger, S. M.; Litzow, M. R.; Rowe, J. M.; Paietta, E. M.; Stock, W.; Dick, J. E.; Mullighan, C. G.
10.1101/2023.12.04.569954 — cancer biology — Posted on 2023-12-09
3090 Single-Molecule RNA Sizing Enables Quantitative Analysis of Alternative Transcription Termination
Patino-Guillen, G.; Pesovic, J.; Panic, M.; Savic-Pavicevic, D.; Boskovic, F.; Keyser, U. F.
10.1101/2023.07.14.549052 — biophysics — Posted on 2023-12-09
3091 Structural basis of connexin-36 gap junction channel inhibition
Ding, X.; Aureli, S.; Vaithia, A.; Lavriha, P.; Schuster, D.; Khanppnavar, B.; Li, X.; Blum, T. B.; Picotti, P.; Gervasio, F. L.; Korkhov, V. M.
10.1101/2023.12.09.570920 — biophysics — Posted on 2023-12-09
3092 Electrostatic encoding of genome organization principles within single native nucleosomes
Park, S.; Athreya, A.; Carrizo, G.; Benning, N.; Mitchener, M.; Bhanu, N.; Garcia, B.; Zhang, B.; Muir, T. W.; Pearce, E.; Ha, T.
10.1101/2023.12.08.570828 — biophysics — Posted on 2023-12-09
3093 Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis
Cossmann, J.; Kos, P. I.; Varamogianni-Mamatsi, V.; Assenheimer, D.; Bischof, T.; Kuhn, T.; Vomhof, T.; Papantonis, A.; Giorgetti, L.; Gebhardt, J. C. M.
10.1101/2023.12.08.570809 — biophysics — Posted on 2023-12-09
3096 Ultrasound programmable hydrogen-bonded organic frameworks for sono-chemogenetics
Wang, W.; Shi, Y.; Chai, W.; Tang, K. W. K.; Pyatnitskiy, I.; Xie, Y.; Liu, X.; He, W.; Jeong, J.; Hsieh, J.-C.; Lozano, A. R.; Artman, B.; Henkelman, G.; Chen, B.; Wang, H.
10.1101/2023.12.08.570721 — bioengineering — Posted on 2023-12-09
3097 Activity of FoxP2-positive neurons correlate with tadpole begging behavior
Ludington, S. C.; McKinney, J. E.; Butler, J. M.; Gaines-Richardson, M.; O'Connell, L. A.
10.1101/2023.05.26.542531 — animal behavior and cognition — Posted on 2023-12-09
3100 NS2B-D55E and NS2B-E65D Variations are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model
Wahaab, A.; Zhang, Y.; Rasgon, J. L.; Kang, L.; Hameed, M.; Li, C.; Anwar, M. N.; Zhang, Y.; Shoaib, A.; Liu, K.; Li, B.; Wei, J.; Qiu, Y.; Ma, Z.
10.1101/2023.12.08.570834 — microbiology — Posted on 2023-12-09
3103 Movement-related increases in subthalamic activity optimize locomotion
Callahan, J. W.; Morales, J. C.; Atherton, J. F.; Wang, D.; Kostic, S.; Bevan, M. D.
10.1101/2023.12.07.570617 — neuroscience — Posted on 2023-12-09
3105 High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen
Yang, W.-p.; Li, M.-q.; Ding, J.; Li, J.-y.; Wu, G.; Liu, B.; Gao, Y.-q.; Wang, G.; Luo, Q.-q.
10.1101/2023.03.23.533972 — physiology — Posted on 2023-12-09
3106 WWOX promotes osteosarcoma development via upregulation of Myc
Akkawi, R.; Hidmi, O.; Haj Yahia, A.; Monin, J.; Diment, J.; Drier, Y.; Stein, G. S.; Aqeilan, R. I.
10.1101/2023.03.14.532523 — cancer biology — Posted on 2023-12-09
3107 Two transcriptional cascades orchestrate cockroach leg regeneration
Ren, C.; Wen, Y.; Zheng, S.; Zhao, Z.; Li, E. Y.; Zhao, C.; Liao, M.; Li, L.; Zhang, X.; Liu, S.; Yuan, D.; Wang, W.; Fei, J.-F.; Li, S.
10.1101/2023.12.09.570905 — developmental biology — Posted on 2023-12-09
3110 A rapid method for generating transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells.
Dalleywater, W.; Predeus, A. V.; Cakir, B.; Mazin, P.; Vadakekolathu, J.; Rutella, S.; Meakin, M. L.; Ritchie, A. A.; Montazid, S.; Cuevas Ocana, S.; Holmes, N.; Wright, V.; Seng, F.; Bills, A.; Sculthorpe, D.; Elmentaite, R.; Teichmann, S. A.; Irshad, S.; Tomlinson, I.; Silver, A.; Wildman, R. D.; Hannan, N. R. F.; Rose, F. R.; Ilyas, M.
10.1101/2023.12.08.570795 — cell biology — Posted on 2023-12-09
3111 Targeting F-actin stress fibers to suppress the dedifferentiated phenotype in chondrocytes
Schofield, M. M.; Rzepski, A.; Hammerstedt, J.; Shah, S.; Mirack, C.; Parreno, J.
10.1101/2023.12.08.570865 — cell biology — Posted on 2023-12-09
3113 Do you have enough space? Habitat selection of insectivorous cave-dwelling bats in fragmented landscapes of Eastern Amazon
Tavares, V. d. C.; Ribeiro, M. S.; Prous, X.; Notini, A. A.; Kaku-Oliveira, N. Y.; Maciel, L. M. D.; Sales, S.; Longo, J. M.; Evangelista, F. M.; Rabelo, L.; Brandi, I.; Vasconcelos, S. S.; Talamoni, S. S.; Oliveira, G.; Trevelin, L. C.
10.1101/2023.12.07.570662 — ecology — Posted on 2023-12-09
3117 Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging
Kirchgaessner, R.; Watson, C.; Creason, A. L.; Keutler, K.; Goecks, J.
10.1101/2023.12.05.570058 — cancer biology — Posted on 2023-12-09
3118 State-transition Modeling of Blood Transcriptome Predicts Disease Evolution and Treatment Response in Chronic Myeloid Leukemia
Frankhouser, D. E.; Rockne, R. C.; Uechi, L.; Zhao, D.; Branciamore, S.; O'Meally, D.; Irizarry, J.; Ghoda, L.; Ali, H.; Trent, J.; Forman, S.; Fu, Y.-H.; Kuo, Y.-H.; Zhang, B.; Marcucci, G.
10.1101/2023.10.11.561908 — cancer biology — Posted on 2023-12-09
3121 A foundational atlas of autism protein interactions reveals molecular convergence
Wang, B.; Vartak, R.; Zaltsman, Y.; Naing, Z. Z. C.; Hennick, K. M.; Polacco, B. J.; Bashir, A.; Eckhardt, M.; Bouhaddou, M.; Xu, J.; Sun, N.; Lasser, M.; Zhou, Y.; Guiley, K. Z.; Chan, U.; Kaye, J. A.; Khare, P.; Drake, S.; Drury, V.; Burke, D. F.; Gonzalez, S.; Alkhairy, S.; Morris, M.; Baum, T.; Krasnoff, R.; Wang, S.; Pham, P.; Arbalaez, J.; Pratt, D.; Chag, S.; Rolland, T.; Bourgeron, T.; Finkbeiner, S.; Bandyopadhay, S.; Ideker, T.; Beltrao, P.; Willsey, H. R.; Obernier, K.; Nowakowski, T. J.; Huttenhain, R.; State, M. W.; Willsey, A. J.; Krogan, N. J.
10.1101/2023.12.03.569805 — systems biology — Posted on 2023-12-09
3122 Amyloid β accelerates age-related proteome-wide protein insolubility.
Anderton, E.; Chamoli, M.; Bhaumik, D.; King, C. D.; Xie, X.; Foulger, A.; Andersen, J.; Schilling, B.; Lithgow, G.
10.1101/2023.07.13.548937 — systems biology — Posted on 2023-12-09
3124 Role of auditory feedback for vocal production learning in the Egyptian fruit-bat
Elie, J. E.; Muroy, S. E.; Genzel, D.; Na, T.; Beyer, L. A.; Swiderski, D. L.; Raphael, Y.; Yartsev, M. M.
10.1101/2023.11.21.568126 — animal behavior and cognition — Posted on 2023-12-09
3125 Functional identification of cis-regulatory long noncoding RNAs at controlled false-discovery rates
Dhaka, B.; Zimmerli, M.; Hanhart, D.; Moser, M.; Guillen-Ramirez, H. A.; Mishra, S.; Esposito, R.; Polidori, T.; Widmer, M.; Garcia-Perez, R.; Kruithof-de Julio, M.; Pervouchine, D. D.; Mele, M.; Chouvardas, P.; Johnson, R.
10.1101/2022.09.18.508380 — genomics — Posted on 2023-12-09
3129 Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure
Girard-Tercieux, C.; Vieilledent, G.; Clark, A. T.; Clark, J. S.; Courbaud, B.; Fortunel, C.; Kunstler, G.; Pelissier, R.; Rueger, N.; Marechaux, I.
10.1101/2022.08.06.503032 — ecology — Posted on 2023-12-09
3130 The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
Dengjel, J.; Siva Sankar, D.; Kaeser-Pebernard, S.; Vionnet, C.; Favre, S.; Oliveira De Marchioro, L.; Pillet, B.; Zhou, J.; Kovacs, W. J.; Kressler, D.; Antonioli, M.; Fimia, G. M.
10.1101/2023.12.08.570815 — cell biology — Posted on 2023-12-09
3131 Structure, interaction, and nervous connectivity of beta cell primary cilia
Müller, A.; Klena, N.; Pang, S.; Garcia, L. E. G.; Sulaymankhil, D.; Topcheva, O.; Seliskar, M.; Mziaut, H.; Schöniger, E.; Friedland, D.; Kipke, N.; Kretschmar, S.; Münster, C.; Weitz, J.; Distler, M.; Kurth, T.; Schmidt, D.; Hess, H. F.; Xu, C. S.; Pigino, G.; Solimena, M.
10.1101/2023.12.01.568979 — cell biology — Posted on 2023-12-09
3134 Viral gene drive spread during herpes simplex virus 1 infection in mice
Walter, M.; Riley, R.; Haick, A. K.; Massa, P. A.; Strongin, D. E.; Klouser, L. M.; Loprieno, M. A.; Stensland, L.; Santo, T. K.; Taylor, M. P.; Jerome, K. R.; Verdin, E.
10.1101/2023.12.07.570711 — microbiology — Posted on 2023-12-09
3135 Ligand requirements for immunoreceptor triggering
Barton, M. I.; Paterson, R. L.; Denham, E. M.; Goyette, J.; van der Merwe, P. A.
10.1101/2023.09.11.557203 — immunology — Posted on 2023-12-09
3137 Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components
Smith, D. M.; Parekh, P.; Kennedy, J.; Loughnan, R. J.; Frei, O.; Nichols, T. E.; Andreassen, O. A.; Jernigan, T. L.; Dale, A. M.
10.1101/2023.07.17.549390 — neuroscience — Posted on 2023-12-09
3139 Transcriptional Cartography Integrates Multiscale Biology of the Human Cortex
Wagstyl, K.; Adler, S.; Seidlitz, J.; Vandekar, S.; Mallard, T. T.; Dear, R.; DeCasien, A. R.; Satterthwaite, T. T.; Liu, S.; Vertes, P. E.; Shinohara, R. T.; Alexander-Bloch, A.; Geschwind, D. H.; Raznahan, A.
10.1101/2022.06.13.495984 — neuroscience — Posted on 2023-12-09
3140 Two distinct modes of hemodynamic responses in the human brain
Epp, S. M.; Castrillon, G.; Andrews-Hanna, J.; Preibisch, C.; Riedl, V.
10.1101/2023.12.08.570806 — neuroscience — Posted on 2023-12-09
3142 Category-based attention facilitates memory search
Shang, L.; Yeh, L.-C.; Zhao, Y.; Wiegand, I.; Peelen, M. V.
10.1101/2023.12.08.570779 — neuroscience — Posted on 2023-12-09
3143 Rhythmic sampling of multiple decision alternatives in the human brain
Siems, M.; Cao, Y.; Tohidi-Moghaddam, M.; Donner, T. H.; Tsetsos, K.
10.1101/2023.12.08.570734 — neuroscience — Posted on 2023-12-09
3145 behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments
Bowler, J. C.; Zakka, G.; Yong, H. C.; Li, W.; Rao, B.; Liao, Z.; Priestley, J. B.; Losonczy, A.
10.1101/2023.12.04.569989 — neuroscience — Posted on 2023-12-09
3151 c-Maf and Mafb function combinatorially to establish SGN subtype-specific synaptic properties
Bastille, I.; Lee, L.; Moncada-Reid, C.; Yu, W.-M.; Sitko, A.; Yung, A.; Goodrich, L.
10.1101/2023.10.18.562788 — neuroscience — Posted on 2023-12-09
3152 Visual deprivation during mouse critical period reorganizes network-level functional connectivity
Chen, S.; Rahn, R. M.; Bice, A. R.; Gaines, S. H.; Padawer-Curry, J. A.; Hengen, K. B.; Dougherty, J. D.; Culver, J. P.
10.1101/2023.05.30.542957 — neuroscience — Posted on 2023-12-09
3155 A layer-specific model of cortical sensory aging
Liu, P.; Doehler, J.; Henschke, J. U.; Northall, A.; Serian, A.; Schwarzkopf, D. S.; Speck, O.; Pakan, J. M. P.; Kuehn, E.
10.1101/2023.12.01.567841 — neuroscience — Posted on 2023-12-09
3156 Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy
Quinn, S.; Zhang, N.; Fenton, T. A.; Brusel, M.; Muruganandam, P.; Peleg, Y.; Giladi, M.; Haitin, Y.; Lerche, H.; Bassan, H.; Liu, Y.; Ben-Shalom, R.; Rubinstein, M.
10.1101/2023.12.04.569940 — physiology — Posted on 2023-12-09
3159 A sexually dimorphic hepatic cycle of very low density lipoprotein uptake and assembly
Martini, T.; Gobet, C.; Salati, A.; Blanc, J.; Mookhoek, A.; Knott, G.; Sordet-Dessimoz, J.; Naef, F.
10.1101/2023.10.07.561324 — physiology — Posted on 2023-12-08
3160 A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Andradi-Brown, C.; Wichers-Misterek, J. S.; von Thien, H.; Hoeppner, Y. D.; Scholz, J. A. M.; Smedegaard Hansson, H.; Filtenborg Hocke, E.; Gilberger, T. W.; Duffy, M.; Lavstsen, T.; Baum, J.; Otto, T. D.; Cunnington, A. J.; Bachmann, A.
10.1101/2023.03.21.533599 — bioinformatics — Posted on 2023-12-08
3161 Comparison of the mechanism of antimicrobial action of the gold(I) compound auranofin in Gram-positive and Gram-negative bacteria
Quadros Barse, L.; Ulfig, A.; Varatnitskaya, M.; Vazquez-Hernandez, M.; Yoo, J.; Imann, A. M.; Lupilov, N.; Becker, K.; Fischer, M.; Bandow, J. E.; Leichert, L. I.
10.1101/2023.12.04.569911 — biochemistry — Posted on 2023-12-08
3162 Resilience of genetic diversity in forest trees over the Quaternary
Milesi, P.; Kastally, C.; Dauphin, B.; Cervantes, S.; Bagnoli, F.; Budde, K. B.; Cavers, S.; Fady, B.; Faivre-Rampant, P.; Gonzalez-Martinez, S. C.; Grivet, D.; Gugerli, F.; Jorge, V.; Lesur Kupin, I.; Ojeda, D. I.; Olsson, S.; Opgenoorth, L.; Pinosio, S.; Plomion, C.; Rellstab, C.; Rogier, O.; Scalabrin, S.; Scotti, I.; Vendramin, G. G.; Westergren, M.; GenTree Consortium, ; Lascoux, M.; Pyhajarvi, T.
10.1101/2023.01.05.522822 — evolutionary biology — Posted on 2023-12-08
3165 Characterisation of protective vaccine antigens from the thiol-containing components of excretory/secretory material of Ostertagia ostertagi
Price, D. R. G.; Steele, P.; Frew, D.; McLean, K.; Androscuk, D.; Geldhof, P.; Borloo, J.; Palarea-Albaladejo, J.; Nisbet, A. J.; McNeilly, T. N.
10.1101/2023.12.08.570749 — zoology — Posted on 2023-12-08
3171 pyRBDome: A comprehensive computational platform for enhancing and interpreting RNA-binding proteome data
Chu, L.-C.; Christopoulou, N.; McCaughan, H.; Winterbourne, S.; Cazzola, D.; Wang, S.; Litvin, U.; Brunon, S.; Harker, P. J. B.; McNae, I.; Granneman, S.
10.1101/2023.12.08.570608 — systems biology — Posted on 2023-12-08
3172 ProteinGym: Large-Scale Benchmarks for Protein Design and Fitness Prediction
Notin, P.; Kollasch, A. W.; Ritter, D.; van Niekerk, L.; Paul, S.; Spinner, H.; Rollins, N.; Shaw, A.; Weitzman, R.; Frazer, J.; Dias, M.; Franceschi, D.; Orenbuch, R.; Gal, Y.; Marks, D. S.
10.1101/2023.12.07.570727 — synthetic biology — Posted on 2023-12-08
3173 Targeted protein degradation systems to enhance Wnt signaling
Sampathkumar, P.; Jung, H.; Chen, H.; Zhang, Z.; Suen, N.; Yang, Y.; Huang, Z.; Lopez, T.; Benisch, R.; Lee, S.-J.; Ye, J.; Yeh, W.-C.; Li, Y.
10.1101/2023.12.08.570758 — synthetic biology — Posted on 2023-12-08
3174 A 3-component module maintains sepal flatness in Arabidopsis
Xu, S.; He, X.; Chi, T. D.; Zhang, X.; Wu, X.; Qiu, D.; Zhou, M.; Xiang, D.; Roeder, A. H. K.; Hamant, O.; Hong, L.
10.1101/2023.12.06.570430 — plant biology — Posted on 2023-12-08
3175 Carbon usage in yellow-fleshed Manihot esculenta storage roots shifts from starch biosynthesis to cell wall and raffinose biosynthesis via the myo-inositol pathway
Gutschker, S.; Ruescher, D.; Rabbi, I. Y.; Rosado de Souza, L.; Pommerrenig, B.; van Doorn, A.; Schlereth, A.; Neuhaus, H. E.; Fernie, A. R.; Reinert, S.; Sonnewald, U.; Zierer, W.
10.1101/2023.12.07.570373 — plant biology — Posted on 2023-12-08
3176 Application of slow-controlled release fertilizer coordinates the carbon flow in carbon-nitrogen metabolism to effect rice quality
Jiang, Z.; Chen, Q.; Liu, D.; Tao, W.; Gao, S.; Li, J.; Lin, C.; Zhu, M.; Ding, Y.; Li, W.; Li, G.; Sakr, S.; Hong, X.
10.1101/2023.12.07.570515 — plant biology — Posted on 2023-12-08
3181 OsUVR8b, rather than OsUVR8a, plays a predominant role in rice UVR8-mediated UV-B response.
Chen, Y.-l.; Zhong, Y.-b.; Leung, D.; Yan, X.-y.; Ouyang, M.-n.; Ye, Y.-z.; Li, S.-m.; Peng, X.; Liu, E.-e.
10.1101/2023.12.07.570679 — plant biology — Posted on 2023-12-08
3182 Nodule organogenesis in Medicago truncatula requires local stage-specific auxin biosynthesis and transport
Xiao, T. T.; Shen, D.; Muller, S.; Liu, J.; van Seters, A.; Franssen, H. J.; Bisseling, T.; Kulikova, O.; Kohlen, W.
10.1101/2023.12.07.570677 — plant biology — Posted on 2023-12-08
3184 Haplo-pheno association for OsNRT1.1 paralog in rice reveals superior haplogroup with high nitrate uptake efficiency
Elangovan, D.; Pandey, R.; Sharma, S.; Balamurugan, B.; Anand, N.; Das, A.; Kumar, T.; Ellur, R. K.; Kalia, S.; Rane, J.
10.1101/2023.12.07.570681 — plant biology — Posted on 2023-12-08
3186 Variations in cellular unfolded protein response, respiratory capacity, and stress tolerance in skin and lung fibroblasts of deer mice (Peromyscus maniculatus)
Yap, K. N.; Yamada, K.; Zikeli, S. L.; Zhang, Y.; Zhang, Y.; Naderi, A.; Soltanmohammadi, E.; Kavazis, A. N.; Roberts, M. D.; Kiaris, H.; Hood, W. R.
10.1101/2023.12.07.570632 — physiology — Posted on 2023-12-08
3187 Lithocholic acid phenocopies rejuvenating and life-extending effects of calorie restriction
Qu, Q.; Chen, Y.; Wang, Y.; Long, S.; Wang, W.; Yang, H.-Y.; Li, M.; Tian, X.; Wei, X.; Liu, Y.-H.; Xu, S.; Zhang, C.; Zhu, M.; Lam, S. M.; Wu, J.; Zhang, B.; Zheng, Z.-Z.; Piao, H.-l.; Shui, G.; Deng, X.; Zhang, C.-S.; Lin, S.-C.
10.1101/2023.12.07.570559 — physiology — Posted on 2023-12-08
3188 Escape problem of magnetotactic bacteria - physiological magnetic field strength help magnetotactic bacteria navigate in simulated sediments
Codutti, A.; Charsooghi, M.; Marx, K.; Cerda-Donate, E.; Munoz, O.; Zaslansky, P.; Telezki, V.; Robinson, T.; Faivre, D.; Klumpp, S.
10.1101/2023.12.08.570788 — biophysics — Posted on 2023-12-08
3190 pIGLET: Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish
Lalonde, R. L.; Wells, H. H.; Kemmler, C. L.; Nieuwenhuize, S.; Lerma, R.; Burger, A.; Mosimann, C.
10.1101/2023.12.08.570868 — genetics — Posted on 2023-12-08
3193 Byproducts of inflammatory radical metabolism provide transient nutrient niches for microbes in the inflamed gut
Spiga, L.; Winter, M. G.; Muramatsu, M.; Rojas, V.; Chanin, R.; Zhu, W.; Hughes, E. R.; Taylor, S.; Faber, F.; Porwollik, S.; Carvalho, T.; Qin, T.; Santos, R.; Andrews-Polymenis, H. L.; McClelland, M.; Winter, S. E.
10.1101/2023.12.08.570695 — microbiology — Posted on 2023-12-08
3195 Replication-attenuated r3LCMV vectors potentiate tumor control via IFN-I
Chung, Y. R.; Awakoaiye, B.; Dangi, T.; Fourati, S.; Penaloza-MacMaster, P.
10.1101/2023.12.08.570847 — immunology — Posted on 2023-12-08
3196 Tuft cell-derived acetylcholine is an effector of type 2 immunity and directly targets helminth parasites in the gut lumen
Ndjim, M.; Herbert, F.; Gasmi, I.; Josephine, C.; Henry, S.; Turtoi, E.; Thirard, S.; Giordano, A.; Ciancia, C.; Britton, C.; Devaney, E.; McNeilly, T. N.; Berrard, S.; Turtoi, A.; Maizels, R. M.; Gerbe, F.; Jay, P.
10.1101/2023.12.08.570757 — immunology — Posted on 2023-12-08
3197 Lithocholic acid targets TULP3 to activate sirtuins and AMPK to retard ageing
Qu, Q.; Chen, Y.; Wang, Y.; Long, S.; Wang, W.; Yang, H.-Y.; Wu, J.; Li, M.; Tian, X.; Wei, X.; Liu, Y.-H.; Xu, S.; Yang, C.; Wu, Z.; Huang, X.; Xie, C.; Wu, Y.; Xu, Z.; Zhang, C.; Zhang, B.; Feng, J.-W.; Chen, J.; Sun, B.; Piao, H.-l.; Xie, X.-S.; Deng, X.; Zhang, C.-S.; Lin, S.-C.; Lin, L.; Xie, Z.; Yu, Y.
10.1101/2023.12.07.570558 — physiology — Posted on 2023-12-08
3200 Age-dependent RGS5 loss in pericytes induces cardiac dysfunction and fibrosis in the heart
Tamiato, A.; Tombor, L. S.; Fischer, A.; Muhly-Reinholz, M.; Vanicek, L. R.; Togru, B. N.; Neitz, J.; Glaser, S. F.; Merten, M.; Rodriguez Morales, D.; Kwon, J.; Klatt, S.; Schuhmacher, B.; Guenther, S.; Abplanalp, W. T.; John, D.; Fleming, I.; Wettschureck, N.; Dimmeler, S.; Luxan, G.
10.1101/2023.12.08.570774 — physiology — Posted on 2023-12-08
3204 Structural Insights into The Role of MAGEA4 in RAD18 Regulation: Implications for Ubiquitin Ligase-Binding across the MAGE Protein Family
Griffith-Jones, S.; Alvarez, L.; Mukhopadhyay, U.; Gharbi, S.; Rettel, M.; Adams, M.; Hennig, J.; Bhogaraju, S.
10.1101/2023.12.08.570772 — biochemistry — Posted on 2023-12-08
3205 Ovothiol is a redundant part of a complex thiol network in promastigote Leishmania mexicana
Bolton, V. L.; Morrison, L. L.; Khanra, S.; Ritchie, R.; Hargrave, K. E.; Burchmore, R. J. S.; MacLeod, M. K. L.; Barrett, M. P.
10.1101/2023.12.08.570742 — biochemistry — Posted on 2023-12-08
3206 Cooperative Gsx2-DNA Binding Requires DNA Bending and a Novel Gsx2 Homeodomain Interface
Webb, J.; Farrow, E.; Cain, B.; Yuan, Z.; Yarawsky, A.; Schoch, E.; Gagliani, E. K.; Herr, A. B.; Gebelein, B.; Kovall, R. A.
10.1101/2023.12.08.570805 — biochemistry — Posted on 2023-12-08
3207 The genomes of the Macadamia genus
Sharma, P.; Masouleh, A.; Constantin, L.; Topp, B.; Furtado, A.; Henry, R. J.
10.1101/2023.12.07.570730 — genomics — Posted on 2023-12-08
3208 GeneMAP: A discovery platform for metabolic gene function
Birsoy, K.; Gamazon, E.; Khan, A.; Unlu, G.; Lin, P.; Liu, Y.; Kilic, E.; Kenny, T. C.
10.1101/2023.12.07.570588 — genomics — Posted on 2023-12-08
3209 Newly obtained genome of fungi-related amoeba is enriched with genes shared with animals-related protists
Pozdnyakov, I.; Potapenko, E. V.; Kalashnikova, V. M.; Barzasekova, C. O.; Zlatogursky, V. V.; Sukhanova, K. M.; Babenko, V. V.; Boldyreva, D. I.
10.1101/2023.12.07.570557 — genomics — Posted on 2023-12-08
3211 MLL3/MLL4 enzymatic activity shapes DNA replication timing
Goekbuget, D.; Boileau, R. M.; Lenshoek, K.; Blelloch, R.
10.1101/2023.12.07.569680 — genomics — Posted on 2023-12-08
3212 Atlas of nascent RNA transcripts reveals enhancer to gene linkages
Sigauke, R. F.; Sanford, L.; Maas, Z. L.; Jones, T.; Stanley, J. T.; Townsend, H. A.; Allen, M. A.; Dowell, R. D.
10.1101/2023.12.07.570626 — genomics — Posted on 2023-12-08
3213 The mutational landscape of Staphylococcus aureus during colonisation
Coll, F.; Blane, B.; Bellis, K.; Matuszewska, M.; Jamrozy, D.; Toleman, M.; Geoghegan, J. A.; Parkhill, J.; Massey, R. C.; Peacock, S. J.; Harrison, E. M.
10.1101/2023.12.08.570284 — genomics — Posted on 2023-12-08
3219 Synchrotron-source micro-x-ray computed tomography for examining butterfly eyes
Paukner, D.; Wildenberg, G. A.; Badalamente, G. S.; Littlewood, P. B.; Kronforst, M. R.; Palmer, S. E.; Kasthuri, N.
10.1101/2023.12.08.570583 — ecology — Posted on 2023-12-08
3220 Tail Length and E525K Dilated Cardiomyopathy Mutant Alter Human β-Cardiac Myosin Super-Relaxed State
Duno-Miranda, S.; Nelson, S. R.; Rasicci, D. V.; Bodt, S. L. M.; Cirilo, J. A.; Vang, D.; Sivaramakrishnan, S.; Yengo, C. M.; Warshaw, D. M.
10.1101/2023.12.07.570656 — molecular biology — Posted on 2023-12-08
3222 The Cryptocococcus extracellular vesicle transcriptome
Taheraly, A.; Maufrais, C.; Moyrand, F.; Coppee, J.-Y.; Colin, J.; Janbon, G.
10.1101/2023.12.08.570810 — microbiology — Posted on 2023-12-08
3224 Spermidine suppresses DC activation via eIF5A hypusination and metabolic adaptation
Meehan, G. R.; Gunes, U.; Scales, H. E.; Finney, G.; Deehan, R.; Sintoris, S.; Athanasiadou, A.; Brewer, J. M.
10.1101/2023.12.07.570665 — immunology — Posted on 2023-12-08
3225 Movement-related increases in subthalamic activity optimize locomotion
Callahan, J. W.; Morales, J. C.; Atherton, J. F.; Wang, D.; Kostic, S.; Bevan, M. D.
10.1101/2023.12.07.570617 — neuroscience — Posted on 2023-12-08
3226 Direct stimulation of anterior insula and ventromedial prefrontal cortex disrupts economic choices
Cecchi, R.; Collomb-Clerc, A.; Rachidi, I.; Minotti, L.; Kahane, P.; Pessiglione, M.; Bastin, J.
10.1101/2023.12.07.570630 — neuroscience — Posted on 2023-12-08
3231 Systematic benchmarking of imaging spatial transcriptomics platforms in FFPE tissues
Wang, H.; Huang, R.; Nelson, J.; Gao, C.; Trans, M.; Yeaton, A.; Felt, K.; Pfaff, K. L.; Bowman, T.; Rodig, S. J.; Wei, K.; Goods, B. A.; Farhi, S. L.
10.1101/2023.12.07.570603 — cancer biology — Posted on 2023-12-08
3236 Machine Learning Elucidates Design Features of Plasmid DNA Lipid Nanoparticles for Cell Type-Preferential Transfection
Cheng, L.; Zhu, Y.; Ma, J.; Aggarwal, A.; Toh, W. H.; Shin, C.; Sangpachatanaruk, W.; Weng, G.; Kumar, R.; Mao, H.-Q.
10.1101/2023.12.07.570602 — bioengineering — Posted on 2023-12-08
3237 Adapting to changing methodology in a long-term experiment
McNamara Manning, K.; Perrone, J.; Petrycki, S.; Landis, D. A.; Bahlai, C.
10.1101/2023.12.07.570659 — ecology — Posted on 2023-12-08
3238 Differential effects of MATR3 variants on its cryptic splicing repression function
Khan, M.; Chen, X. X. L.; Dias, M.; Santos, J. R.; Kour, S.; You, J.; van Bruggen, R.; Youssef, M.; Wan, Y.-W.; Liu, Z.; Rosenfeld, J. A.; Tan, Q.; Pandey, U. B.; Yalamanchili, H. K.; Park, J.
10.1101/2023.12.07.570685 — molecular biology — Posted on 2023-12-08
3239 snPATHO-seq: unlocking the pathology archives
Wang, T.; Harvey, K.; Escudero Morales, J.; Kiedik, B.; Al-Eryani, G.; Greenwald, A. C.; Kalavros, N.; SegatovDezem, F.; Ma, Y.; Pita-Juarez, Y.; Wise, K.; Degletagne, C.; Elz, A.; Johanneson, J.; Pakiam, F.; Ryu, H.; Newell, E. W.; Tonon, L.; Kohlway, A.; Drennon, T.; Hadadianpour, A.; Abousoud, J.; Scott, R.; Lund, P.; Durruthy, J.; Vallejos, A. F.; Kaczorowski, D.; Warren, J.; Butler, L. M.; O'Toole, S.; Plummer, J. T.; Vlachos, I.; Lundeberg, J.; Swarbrick, A.; Martelotto, L. G.
10.1101/2023.12.07.570700 — molecular biology — Posted on 2023-12-08
3242 High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster
Darby, A. M.; Okoro, D. O.; Aredas, S. N.; Frank, A. M.; Pearson, W. H.; Dionne, M. S.; Lazzaro, B. P.
10.1101/2023.12.07.570705 — immunology — Posted on 2023-12-08
3243 The dysregulated IL-23/TH17 axis in endometriosis pathophysiology
Sisnett, D. J.; Zutautas, K. B.; Miller, J. E.; Lingegowda, H.; Ahn, S. H.; McCallion, A.; Bougie, O.; Lessey, B. A.; Tayade, C.
10.1101/2023.12.07.570652 — immunology — Posted on 2023-12-08
3244 A semi-automated cell tracking protocol for quantitative analyses of neutrophil swarming to sterile and S. aureus contaminated bone implants in a mouse femur model
Lekkala, S.; Ren, Y.; Weeks, J.; Lee, K.; Tay, A. J. H.; Liu, B.; Xue, T.; Rainbolt, J.; Xie, C.; Schwarz, E. M.; Yeh, S.-C. A.
10.1101/2023.12.07.570663 — immunology — Posted on 2023-12-08
3250 Not dasycladalean alga, but an Odyssey of the earliest Phanerozoic animal reef-builders
Yang, A.; Luo, C.; Han, J.; Zhuravlev, A. Y.; Reitner, J.; Sun, H.; Zeng, H.; Zhao, F.; Hu, S.
10.1101/2023.12.07.570709 — paleontology — Posted on 2023-12-08
3253 KatG inactivation generates vulnerabilities in isoniazid resistant strains of Mycobacterium tuberculosis
Wang, X.; Jowsey, W. J.; Cheung, C.-Y.; Seeto, N. E.; Waller, N. J.; Chrisp, M. T.; Peterson, A. L.; Nijagal, B.; Fineran, P. C.; Cook, G. M.; Jackson, S. A.; McNeil, M. B.
10.1101/2023.12.07.570702 — microbiology — Posted on 2023-12-08
3254 INHBA/Activin A promotes tumor growth and induces resistance to anti-PD-L1 therapy by suppressing IFN-γ signaling
Li, F.; Gu, L.; Tong, Y.; Yu, X.; Chen, R.; Liu, N.; Chen, S.; Lu, J.; Si, Y.; Chen, J.; Sun, J.; Long, Y.; Gong, L.
10.1101/2023.12.07.570561 — immunology — Posted on 2023-12-08
3255 Divergent Epigenetic and Transcriptomic Reprogramming of Monocyte Subpopulations in Systemic Lupus Erythematosus
Ferrete-Bonastre, A. G.; Martinez-Gallo, M.; Morante-Palacios, O.; Calvillo, C. L.; Calafell-Segura, J.; Rodriguez-Ubreva, J.; Esteller, M.; Cortes-Hernandez, J.; Ballestar, E.
10.1101/2023.12.07.570725 — immunology — Posted on 2023-12-08
3256 Unraveling the Phenotypic States of Human innate-like T Cells: Comparative Insights with Conventional T Cells and Mouse Models
Loh, L.; Carcy, S.; Krovi, H. S.; Domenico, J.; Spengler, A.; Lin, Y.; Torres, J. D.; Palmer, W.; Norman, P. J.; Stone, M.; Brunetti, T.; Meyer, H. V.; Gapin, L.
10.1101/2023.12.07.570707 — immunology — Posted on 2023-12-08
3258 A common cortical basis for variations in visual crowding
Greenwood, J. A.; Jerotic, K.; Danter, J. E.; Finnie, R. J.; Schwarzkopf, D. S.
10.1101/2023.12.07.570607 — neuroscience — Posted on 2023-12-08
3260 The response to ketogenic diet in colorectal cancer is mediated by lasting functional alterations of the gut microbiome
Tsenkova, M.; Brauer, M.; Kasakin, M.; Busi, S. B.; Schmoetten, M.; Gaigneaux, A.; Pozdeev, V.; Meyers, M.; Koncina, E.; Herebian, D.; Rodriguez, F.; Schmitz, M.; de Nies, L.; Mayatepek, E.; Haan, S.; de Beaufort, C.; Graas, J.; Cramer, T.; Linster, C.; Wilmes, P.; Letellier, E.
10.1101/2023.12.07.570549 — cancer biology — Posted on 2023-12-08
3263 A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.
Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Shepherd, D. P.; Presse, S. P.
10.1101/2023.12.07.570701 — biophysics — Posted on 2023-12-08
3268 Conserved N-terminal Regulation of the ACA8 Calcium Pump with Two Calmodulin Binding Sites
Larsen, S. T.; Dannersoe, J. K.; Nielsen, C. J. F.; Poulsen, L. R.; Palmgren, M.; Nissen, P.
10.1101/2023.12.07.570580 — biochemistry — Posted on 2023-12-08
3270 An improved haplotype resolved genome reveals more rice genes
Abdullah, M.; Furtado, A.; Masouleh, A.; Okemo, P.; Henry, R. J.
10.1101/2023.12.07.570500 — genomics — Posted on 2023-12-08
3272 Cryptic endogenous retrovirus subfamilies in the primate lineage
Chen, X.; Zhang, Z.; Yan, Y.; Goubert, C.; Bourque, G.; Inoue, F.
10.1101/2023.12.07.570592 — genomics — Posted on 2023-12-08
3273 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Munugala, C.; Bloom, J. S.; Kruglyak, L.
10.1101/2023.12.07.570640 — genetics — Posted on 2023-12-08
3278 The role of Miocene-Pleistocene environmental change in diversification of the genus Hypoclinemus Chabanaud, 1928.
Rodrigues, A. E. S.; Ready, J. S.; Pereira da Silva, L. G.; Silva, K. d. F.; Silva, D. J. F.; Sabaj, M. H.; Andrade, M. C.; Vasconcelos, S.; Sales, J. B. L.
10.1101/2023.12.07.570667 — evolutionary biology — Posted on 2023-12-08
3283 Viral gene drive spread during herpes simplex virus 1 infection in mice
Walter, M.; Riley, R.; Haick, A. K.; Massa, P. A.; Strongin, D. E.; Klouser, L. M.; Loprieno, M. A.; Stensland, L.; Santo, T. K.; Taylor, M. P.; Jerome, K. R.; Verdin, E.
10.1101/2023.12.07.570711 — microbiology — Posted on 2023-12-08
3285 Evidence based Unification of poTato gene models with UniTato collaborative genome browser
Zagorscak, M.; Zrimec, J.; Bleker, C.; Nolte, N.; Ramsak, Z.; Gruden, K.; Petek, M.
10.1101/2023.12.07.570586 — plant biology — Posted on 2023-12-08
3289 An epigenome-wide analysis of DNA methylation, racialized and economic inequities, and air pollution
Watkins, S. H.; Testa, C.; Simpkin, A. J.; Davey Smith, G.; Coull, B.; De Vivo, I.; Tilling, K.; Waterman, P. D.; Chen, J. T.; Diez Roux, A. V.; Krieger, N.; Suderman, M.; Relton, C.
10.1101/2023.12.07.570610 — bioinformatics — Posted on 2023-12-08
3292 Modulation of Salmonella virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex.
Yu, X.-J.; Xie, H. X.; Li, Y.; Liu, M.; Hou, R.; Predeus, A.; Perez-Sepulveda, B. M.; Hinton, J.; Holden, D. W.; Thurston, T. L. M.
10.1101/2023.12.07.570645 — microbiology — Posted on 2023-12-08
3293 SARS-CoV-2 infection is associated with intestinal permeability, systemic inflammation, and microbial dysbiosis in hospitalized COVID-19 patients
Basting, C. M.; Langat, R.; Broedlow, C. A.; Guerrero, C.; Bold, T. D.; Bailey, M.; Velez, A.; Schroeder, T.; Short-Miller, J.; Cromarty, R.; Mayer, Z.; Southern, P. J.; Schacker, T. W.; Safo, S. E.; Bramante, C. T.; Tignanelli, C. J.; Schifanella, L.; Klatt, N. R.
10.1101/2023.12.07.570670 — microbiology — Posted on 2023-12-08
3294 Glial swip-10 expression controls systemic mitochondrial function, oxidative stress, and neuronal viability via copper ion homeostasis
Rodriguez, P.; Kalia, V.; Gibson, C. L.; Gichi, Z.; Rajoo, A.; Matier, C. D.; Pezacki, A. T.; Xiao, T.; Carvelli, L.; Chang, C. J.; Miller, G. W.; Khamoui, A. V.; Boerner, J.; Blakely, R. D.
10.1101/2023.12.06.570462 — neuroscience — Posted on 2023-12-08
3300 Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene
Faber, N. R.; Xu, X.; Chen, J.; Hou, S.; Du, J.; Pannebakker, B. A.; Zwaan, B. J.; van den Heuvel, J.; Champer, J.
10.1101/2023.12.07.570117 — genetics — Posted on 2023-12-08
3301 Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population
Vanneste, M.; Hoskens, H.; Goovaerts, S.; Matthews, H.; Aponte, J. D.; Cole, J.; Shriver, M. D.; Marazita, M. L.; Weinberg, S. M.; Walsh, S.; Richmond, S.; Klein, O. D.; Spritz, R. A.; Peeters, H.; Hallgrimsson, B.; Claes, P.
10.1101/2023.12.07.570544 — genetics — Posted on 2023-12-08
3305 Regional differences in synaptic degeneration are linked to alpha-synuclein burden and axonal damage in Parkinson's disease and Dementia with Lewy bodies
Frigerio, I.; Bouwman, M. M.; Noordermeer, R. T.; Podobnik, E.; Popovic, M.; Timmermans, E.; Rozemuller, A. J.; van de Berg, W. D.; Jonkman, L. E.
10.1101/2023.12.07.570569 — neuroscience — Posted on 2023-12-08
3307 Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain
Hopp, S. C.; Garcia Rogers, J.; Smith, S.; Campos, G.; Miller, H.; Barannikov, S.; Gutierrez Kuri, E.; Wang, H.; Han, X.; Bieniek, K. F.; Weintraub, S. T.; Palavicini, J. P.
10.1101/2023.12.06.570499 — neuroscience — Posted on 2023-12-08
3308 Comparative phosphoproteome analysis of primary and metastatic uveal melanoma cell lines
Glinkina, K.; Prieto, R. G.; Teunisse, A. F. A. S.; Gelmi, M. C.; Jager, M. J.; Vertegaal, A. C. O.; Jochemsen, A. G.
10.1101/2023.12.06.570407 — cancer biology — Posted on 2023-12-08
3309 Clustering of HR+/HER2- breast cancer in an Asian cohort is driven by immune phenotypes
Pan, J.-W.; Ragu, M. E.; Chan, W.-Q.; Hasan, S. N.; Islan, T.; Teoh, L.-Y.; Jamaris, S.; See, M.-H.; Yip, C.-H.; Rajadurai, P.; Looi, L.-M.; Mohd Taib, N. A.; Rueda, O. M.; Caldas, C.; Chin, S.-F.; Lim, J.; Teo, S.-H.
10.1101/2023.12.07.570545 — cancer biology — Posted on 2023-12-08
3310 The Exon Junction Complex component EIF4A3 plays a splicing-linked oncogenic role in Pancreatic Ductal Adenocarcinoma
Blazquez-Encinas, R.; Alors-Perez, E.; Moreno-Montilla, M. T.; Garcia-Vioque, V.; Sanchez-Frias, M. E.; Mafficini, A.; Lopez-Canovas, J. L.; Bousquet, C.; Gahete, M. D.; Lawlor, R. T.; Luque, R. M.; Scarpa, A.; Arjona-Sanchez, A.; Pedraza-Arevalo, S.; Ibanez-Costa, A.; Castano, J. P.
10.1101/2023.12.07.570542 — cancer biology — Posted on 2023-12-08
3311 A novel in vitro tubular model to recapitulate features of distal airways: the bronchioid
Maurat, E.; Raasch, K.; Leipold, A.; Henrot, P.; Zysman, M.; Prevel, R.; Trian, T.; Thumerel, M.; Nassoy, P.; Berger, P.; Saliba, A.-E.; Andrique, L.; Recher, G.; Dupin, I.
10.1101/2023.12.06.569771 — physiology — Posted on 2023-12-08
3312 Dynamic Plasticity Systems Direct Early Adaptation to Treatment in Neuroblastoma
Roux, C.; Hamer, S.; Shea, A.; Chen, E.; Sadr, A. S.; English, C.; Sahoo, S.; Allo Anido, A.; Che, H.; Chesler, L.; Jolly, M. K.; Morgan, M. D.; Bruna, A.
10.1101/2023.12.07.570359 — cancer biology — Posted on 2023-12-08
3315 O-glycans Expand Lubricin and Attenuate its Viscosity and Shear Thinning
Boushehri, S.; Holey, H.; Brosz, M.; Gumbsch, P.; Pastewka, L.; Aponte-Santamaria, C.; Graeter, F.
10.1101/2023.12.07.570567 — biophysics — Posted on 2023-12-08
3316 Single-Molecule FRET at 10 MHz Count Rates
Grabenhorst, L.; Sturzenegger, F.; Hasler, M.; Schuler, B.; Tinnefeld, P.
10.1101/2023.12.08.570755 — biophysics — Posted on 2023-12-08
3318 Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS
Adam, L.; Kumar, R.; Arroyo-Garcia, L. E.; Molenkamp, W. H.; Nowak, J. S.; Klute, H.; Farzadfard, A.; Alkenayeh, R.; Nielsen, J.; Biverstal, H.; Otzen, D. E.; Johansson, J.; Abelein, A.
10.1101/2023.12.07.570346 — biophysics — Posted on 2023-12-08
3331 SIRT5 variants from patients with mitochondrial disease are associated with reduced SIRT5 stability and activity, but not with neuropathology
Yuan, T.; Kumar, S.; Skinner, M. E.; Victor-Joseph, R.; Abuaita, M.; Keijer, J.; Zhang, J.; Kunkel, T.; Liu, Y.; Petrunak, E.; Saunders, T.; Lieberman, A. P.; Stuckey, J. A.; Neamati, N.; AlMurshedi, F.; Alfadhel, M.; Spelbrink, J. N.; Rodenburg, R.; de Boer, V. C. J.; Lombard, D. B.
10.1101/2023.12.06.570371 — genetics — Posted on 2023-12-08
3332 Direct targets of MEF2C are enriched for genes associated with schizophrenia and cognitive function and are involved in neurogenesis and mitochondrial function
Ali, D.; Laighneach, A.; Corley, E.; Patlola, S. R.; Holleran, L.; McKernan, D. P.; Kelly, J. P.; Corvin, A. P.; Hallahan, B.; McDonald, C.; Donohoe, G.; Morris, D. W.
10.1101/2023.12.07.570529 — genetics — Posted on 2023-12-08
3335 Linking root-associated fungal and bacterial functions to root economics
Wu, R.; Zeng, X.; McCormack, M. L.; Fernandez, C. W.; Yang, Y.; Guo, H.; Xi, M.; Liu, Y.; Qi, X.; Liang, S.; Juenger, T.; Koide, R. T.; Chen, W.
10.1101/2023.12.06.570504 — ecology — Posted on 2023-12-08
3337 Human monoclonal antibodies reveal subdominant gonococcal and meningococcal cross-protective antigens
Troisi, M.; Fabbrini, M.; Stazzoni, S.; Viviani, V.; Carboni, F.; Abbiento, V.; Fontana, L. E.; Tomei, S.; Audagnotto, M.; Santini, L.; Spagnuolo, A.; Antonelli, G.; Paciello, I.; Vacca, F.; Cardamone, D.; Marini, E.; Mokhtary, P.; Finetti, F.; Giusti, F.; Bodini, M.; Torricelli, G.; Limongi, C.; Del Vecchio, M.; Favaron, S.; Tavarini, S.; Sammicheli, C.; Rossi, A.; Mandelli, A. P.; Fortini, P.; Caffarelli, C.; Gonnelli, S.; Nuti, R.; Baldari, C. T.; Sala, C.; Tagliabue, A.; Savino, S.; Brunelli, B.; Norais, N.; Frigimelica, E.; Bardelli, M.; Pizza, M.; Ros, I. M. Y.; Delany, I.; Finco, O.; An
10.1101/2023.12.07.570438 — immunology — Posted on 2023-12-08
3338 Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1+ macrophages
Yu, J.; Thomas, J.; Haub, J.; Pizarro, C.; Zhang, M.; Biener, L.; Becker, M.; Zhang, L.; Kapellos, T.; Schulte, W.; Schultze, J.; Hasenauer, J.; Skowasch, D.; Schlitzer, A.
10.1101/2023.12.06.569201 — immunology — Posted on 2023-12-08
3339 Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium
Ohigashi, I.; White, A.; Yang, M.-T.; Fujimori, S.; Tanaka, Y.; Jacques, A.; Kiyonari, H.; Matsushita, Y.; Turan, S.; Kelly, M. C.; Anderson, G.; Takahama, Y.
10.1101/2023.10.03.560657 — immunology — Posted on 2023-12-08
3340 FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Parekh, P.; Fan, C. C.; Frei, O.; Palmer, C. E.; Smith, D. M.; Makowski, C.; Iverson, J. R.; Pecheva, D.; Holland, D.; Loughnan, R.; Nedelec, P.; Thompson, W. K.; Hagler, D. J.; Andreassen, O. A.; Jernigan, T. L.; Nichols, T. E.; Dale, A. M.
10.1101/2021.10.27.466202 — neuroscience — Posted on 2023-12-08
3341 Effects of noise and metaboliccost on cortical task representations
Stroud, J. P.; Wojcik, M. J.; Jensen, K. T.; Kusunoki, M.; Kadohisa, M.; Buckley, M. J.; Duncan, J.; Stokes, M. G.; Lengyel, M.
10.1101/2023.07.11.548492 — neuroscience — Posted on 2023-12-08
3343 Metabolomics of Mouse Embryonic CSF Following Maternal Immune Activation
Petrova, B.; Lacey, T. E.; Culhane, A. J.; Cui, J.; Raskin, A.; Mishra, A.; Lehtinen, M. K.; Kanarek, N.
10.1101/2023.12.06.570507 — neuroscience — Posted on 2023-12-08
3344 Brain-wide topographic coordination of traveling spiral waves
Ye, Z.; Bull, M. S.; Li, A.; Birman, D.; Daigle, T. L.; Tasic, B.; Zeng, H.; Steinmetz, N. A.
10.1101/2023.12.07.570517 — neuroscience — Posted on 2023-12-08
3345 Modeling an ultra-rare epilepsy variant in wildtype mice with in utero prime editing
Robertson, C. D.; Davis, P.; Richardson, R. R.; Iffland, P. H.; Vieira, D. C. O.; Steyert, M.; McKeon, P. N.; Romanowski, A. J.; Crutcher, G.; Jasarevic, E.; Wolff, S. B. E.; Mathur, B. N.; Crino, P. B.; Bale, T. L.; Dick, I. E.; Poulopoulos, A.
10.1101/2023.12.06.570164 — neuroscience — Posted on 2023-12-08
3346 Direct Entorhinal Control of CA1 Temporal Coding
Guardamagna, M.; Chadney, O. M. T.; Stella, F.; Zhang, Q.; Kentros, C.; Battaglia, F. P.
10.1101/2023.05.27.542579 — neuroscience — Posted on 2023-12-08
3349 A phosphorylation-dependent switch of the lysosomal V-ATPase assembly regulates α-synuclein clearance in glia
Zhang, S.; Wang, L.; Yi, S.; Li, S.; Wang, H.; Wang, R.; Liu, Y.; Yan, W.; Liu, C.; He, K.-w.; Ho, M. S.
10.1101/2023.12.07.570521 — neuroscience — Posted on 2023-12-08
3350 Apoplastic barrier establishment in roots and nodules of Lotus japonicus is essential for root-shoot signaling and N-fixation
Shen, D.; Venado, R. E.; Neumann, U.; Dyballa-Rukes, N.; Mahiwal, S.; Metzger, S.; Nakano, R. T.; Marin, M.; Andersen, T. G.
10.1101/2023.12.06.570432 — plant biology — Posted on 2023-12-08
3352 CD20 expression regulates CD37 levels in B-cell lymphoma: implications for immunotherapies.
Bobrowicz, M.; Kusowska, A.; Krawczyk, M.; Slusarczyk, A.; Barankiewicz, J.; Domagala, J.; Kubacz, M.; Smida, M.; Dostalova, L.; Marhelava, K.; Fidyt, K.; Forcados, C.; Pepek, M.; Baranowska, I.; Szumera-Cieckiewicz, A.; Inderberg, E. M.; Walchli, S.; Graczyk-Jarzynka, A.; Gehlert, C. L.; Peipp, M.; Firczuk, M.; Prochorec-Sobieszek, M.; Winiarska, M.
10.1101/2023.12.06.570441 — cancer biology — Posted on 2023-12-08
3353 MRTF activity in breast cancer cells promotes osteoclastogenesis through a paracrine action of CTGF
Chawla, P.; Gau, D.; Chen, F.; Welling, N.; Boone, D.; Taboas, J.; LEE, A. V.; Galson, D. L.; Roy, P.
10.1101/2023.12.06.570453 — cancer biology — Posted on 2023-12-08
3354 A novel, RAS-independent role for NF1 in microtubular dynamics and damage repair dictates sensitivity to T-DM1 in HER2-positive breast cancer
Achutti Duso, B.; Messuti, E.; Tini, G.; Bonetti, E.; Castiglioni, A.; Frige, G.; Ciossani, G.; Monzani, S.; Soriani, C.; Khuntsariya, D.; Roda, N.; Polazzi, A.; Ippolito, M. R.; Gavilan Dorronzoro, E.; Mane, E.; Farfalla, A.; Jemos, C.; Guerini Rocco, E.; Rodighero, S.; Tosoni, D.; Santaguida, S.; Braun, M.; Lansky, Z.; Scietti, L. A.; Pelicci, P. G.; Mazzarella, L.
10.1101/2023.12.06.569572 — cancer biology — Posted on 2023-12-08
3355 A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma
Weiner, A. K.; Radaoui, A. B.; Tsang, M.; Martinez, D.; Sidoli, S.; Conkrite, K. L.; Delaidelli, A.; Modi, A.; Rokita, J. L.; Patel, K.; Lane, M. V.; Zhang, B.; Zhong, C.; Ennis, B.; Miller, D. P.; Brown, M. A.; Rathi, K. S.; Raman, P.; Pogoriler, J.; Bhatti, T.; Pawel, B.; Glisovic-Aplenc, T.; Teicher, B.; Erickson, S. W.; Earley, E. J.; Bosse, K. R.; Sorensen, P. H.; Krytska, K.; Mosse, Y. P.; Havenith, K. E.; Zammarchi, F.; van Berkel, P. H.; Smith, M. A.; Garcia, B. A.; Maris, J. M.; Diskin, S. J.
10.1101/2023.12.06.570390 — cancer biology — Posted on 2023-12-08
3361 Adaptable Fabrication of Vascularized Milliscale Tissues in Membrane-Free Organ Chips Manufactured with 3D Printed Molds
Byrne, C. E.; Conrad, K. M.; Martier, A. T.; Fortes, G. M.; Kpeli, G. W.; Olsen, E. A.; Bralower, W.; Culp, C. C.; Wendell, M.; Boone, K. A.; Mondrinos, M. J.
10.1101/2023.12.06.570409 — bioengineering — Posted on 2023-12-08
3364 Spatial ecology and population dynamics of brown trout Salmo trutta L. in reservoirs and headwater tributaries
Dodd, J.; Noble, R. A. A.; Nunn, A. D.; Owen, H. M.; Moccetti, P.; Harvey, J. P.; Wallace, L.; Gillespie, B.; Joyce, D. A.; Bolland, J. D.
10.1101/2023.12.06.570412 — ecology — Posted on 2023-12-08
3366 Mycorrhizal fungi modulate tree diversity effects on nutrient dynamics
Boenisch, E.; Blagodatskaya, E.; Dirzo, R.; Ferlian, O.; Fichtner, A.; Huang, Y.; Leonard, S. J.; Maestre, F. T.; von Oheimb, G.; Ray, T.; Eisenhauer, N.
10.1101/2023.12.06.569218 — ecology — Posted on 2023-12-08
3368 Unravelling neuronal and glial differences in ceramide composition, synthesis, and sensitivity to toxicity
McInnis, J. J.; Sood, D.; Guo, L.; Dufault, M. R.; Garcia, M.; Passaro, R.; Gao, G.; Zhang, B.; Dodge, J. C.
10.1101/2023.12.06.569570 — neuroscience — Posted on 2023-12-08
3369 The Role of Attention in Multi Attribute Decision Making
Sampson, A. L.; Yang, Y.-P.; Usher, M.; Levy, D.; Niebur, E.; Stuphorn, V.
10.1101/2023.12.06.570439 — neuroscience — Posted on 2023-12-08
3370 A new efficacious Mcl-1 inhibitor maximizes bortezomib and venetoclax responsiveness in resistant multiple myeloma cells
Al Odat, O. S. F.; Gowda, K.; Srivastava, S. K.; Amin, S. G.; Jonnalagadda, S. C.; Budak-Alpdogan, T.; Pandey, M. K.
10.1101/2023.12.06.570435 — pharmacology and toxicology — Posted on 2023-12-08
3374 Causal inference for multiple risk factors and diseases from genomics data
Machnik, N.; Mahmoudi, M.; Kraetschmer, I.; Bauer, M. J.; Robinson, M. R.
10.1101/2023.12.06.570392 — genetics — Posted on 2023-12-08
3380 Garden, greenhouse or climate chamber? Experimental conditions influence whether genetic differences are phenotypically expressed
Karitter, P.; March-Salas, M.; Ensslin, A.; Rauschkolb, R.; Godefroid, S.; Poorter, H.; Scheepens, J. F.
10.1101/2023.12.06.570376 — ecology — Posted on 2023-12-08
3382 Imaging the dynamics of uterine contractions in early pregnancy
Dawson, M.; Flores, D.; Zou, L.; Anandhasenthil, S.; Mahesh, R.; Zavala, O.; Arora, R.
10.1101/2023.12.06.570447 — developmental biology — Posted on 2023-12-08
3384 Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis
Denner, A.; Steger, J.; Ries, A.; Morozova-Link, E.; Ritter, J.; Haas, F.; Cole, A. G.; Technau, U.
10.1101/2023.12.07.570436 — developmental biology — Posted on 2023-12-08
3385 Self-renewing Sox9+ osteochondral stem cells in the postnatal skeleton
Farhat, S.; Tilouche, B.; Short, S.; Piron, M.; Campbell, T. M.; Fernandes, A.; Somyk, M.; Bandukwala, H.; Arezza, E.; Sastourne-Arrey, Q.; Reilly, K.; Chakra, M. A.; Bader, G.; Kunz, L.; Schroeder, T.; Carsen, S.; Mattar, P.; Dilworth, J.; Coutu, D. L.
10.1101/2023.12.07.570646 — developmental biology — Posted on 2023-12-08
3387 Development of Pial Collaterals by Extension of Pre-existing Artery Tips
Kumar, S.; Shanavas, N.; Ghosh, S.; Sivaramakrishnan, V.; Dwari, M.; Das, S.
10.1101/2023.12.07.570539 — developmental biology — Posted on 2023-12-08
3390 TGF-beta dynamically controls epithelial identity in a 3D model of human epiblast
Zorzan, I.; Carbognin, E.; Lauria, A.; Proserpio, V.; Benvegnu, D.; Dalrio, C.; Arboit, M.; Paolucci, I.; Drusin, A.; Sledziowska, M.; Amadei, G.; Oliviero, S.; Martello, G.
10.1101/2023.12.07.570575 — developmental biology — Posted on 2023-12-08
3391 Paternally-induced environmental programming of placenta development, offspring birth weight and health phenotypes in a mouse model
Chen, E.; da Cruz, R. S.; Nascimento, A.; Joshi, M.; Pereira, D. G.; Dominguez, O.; Fernandes, G.; Smith, M.; Paiva, S. P. C.; de Assis, S.
10.1101/2023.12.07.570618 — developmental biology — Posted on 2023-12-08
3392 Nuclear VANGL2 Inhibits Lactogenic Differentiation
Rubio, S.; Molinuevo, R.; Sanz-Gomez, N.; Zomorrodinia, T.; Cockrum, C. S.; Luong, E.; Rivas, L.; Cadle, K.; Menendez, J.; Hinck, L.
10.1101/2023.12.07.570706 — cell biology — Posted on 2023-12-08
3393 Depletion of tropomyosin 1.6 promotes matrix-degrading phenotype in TGF-β1-induced myofibroblast
Wu, C. L.; Lee, G.-H.; Chen, B. Y.; Kuo, C.-H.; Chan, T. T.; Wang, Y.-K.; Wong, T. Y.; Tang, M.-J.
10.1101/2023.12.08.570775 — cell biology — Posted on 2023-12-08
3394 Differentiating erythroblasts adapt to turbulent flow by accelerating maturation and activating cholesterol biosynthesis.
Iacono, G.; Abay, A.; Gallego-Murillo, J. S.; Aglialoro, F.; Yagci, N.; Fu, K.; Svendsen, A. F.; von Lindern, M. M.; van den Akker, E.
10.1101/2023.12.08.570773 — cell biology — Posted on 2023-12-08
3395 Endogenous opioid receptor system mediates costly altruism in the human brain
Chen, J.; Putkinen, V.; Seppälä, K.; Hirvonen, J.; Ioumpa, K.; Gazzola, V.; Keysers, C.; Nummenmaa, L.
10.1101/2023.12.06.569026 — neuroscience — Posted on 2023-12-08
3396 Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations
Forrester, E. A.; Benitez-Angeles, B.-A.; Redford, K. E.; Rosenbaum, T.; Abbott, G. W.; Barrese, V.; Dora, K. A.; Albert, A.; Dannesboe, D.; Salles-Crawley, I.; Jepps, T. A.; Greenwood, I. A.
10.1101/2023.12.05.570303 — physiology — Posted on 2023-12-08
3400 Comprehensive chromatome profiling identifies metabolic enzymes on chromatin in healthy and cancer cells
Kourtis, S.; Guirola, M.; Pardo-Lorente, N.; Ghose, R.; Garcia-Cao, M.; Ganez-Zapater, A.; Haynes, S.; Fontaine, F.; Muller, A.; Sdelci, S.
10.1101/2023.12.06.570368 — cancer biology — Posted on 2023-12-08
3402 Fungi and Bacteria Occupy Distinct Spatial Niches within Carious Dentin
Sulyanto, R. M.; Beall, C. J.; Ha, K.; Montesano, J.; Juang, J.; Dickson, J. R.; Hashmi, S. B.; Bradbury, S.; Leys, E. J.; Edgerton, M.; Ho, S. P.; Griffen, A. L.
10.1101/2023.12.05.570240 — microbiology — Posted on 2023-12-08
3403 EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites through Endothelial Fatty Acid Uptake
Pirri, D.; Tian, S.; Tardajos Ayllon, B.; Irving, S.; Donati, F.; Allen, S.; Mammoto, T.; Vilahur, G.; Miller, C. L.; Schenkel, T.; Chambers, E.; Dunning, M. J.; Serbanovic-Canic, J.; Botre, F.; Mammoto, A.; Xu, S.; Osto, E.; Han, W.; Fragiadaki, M.; Evans, P. C.
10.1101/2023.12.05.570309 — physiology — Posted on 2023-12-08
3404 Ergosterol mediates aggregation of natamycin in the yeast plasma membrane
Szomek, M.; Akkerman, V.; Lauritsen, L.; Walther, H.-L.; Juhl, A. D.; Thaysen, K.; Egebjerg, J. M.; Covey, D. F.; Lehmann, M.; Wessig, P.; Foster, A. J.; Poolman, B.; Werner, S.; Schneider, G.; Müller, P.; Wüstner, D.
10.1101/2023.12.05.570146 — biophysics — Posted on 2023-12-08
3405 Filamin protects myofibrils from contractile damage through changes in its mechanosensory region
Gonzalez Morales, N.; Fisher, L. A.; Carriqui-Madronal, B.; Mulder, T.; Huelsmann, S.; Schöck, F.
10.1101/2023.12.08.570741 — cell biology — Posted on 2023-12-08
3407 Endoplasmic reticulum exit sites are segregated for secretion based on cargo size
Saxena, S.; Foresti, O.; Liu, A.; Androulaki, S.; Rodriguez, M. P.; Raote, I.; Cui, B.; Aridor, M.; Malhotra, V.
10.1101/2023.12.07.570627 — cell biology — Posted on 2023-12-08
3410 'Off-pore' nucleoporins relocalize heterochromatic breaks through phase separation
Merigliano, C.; Ryu, T.; See, C. D.; Caridi, C. P.; Butova, N.; Reynolds, T.; Deng, C.; Chenoweth, D. M.; Capelson, M.; Chiolo, I.
10.1101/2023.12.07.570729 — cell biology — Posted on 2023-12-08
3412 Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons
Ott, C. M.; Constable, S.; White, K.; Nguyen, T.; Lee, W.-C. A.; Lippincott-Schwartz, J.; Mukhopadhyay, S.
10.1101/2023.12.07.565988 — cell biology — Posted on 2023-12-08
3413 Segmentation of supragranular and infragranular layers in ultra-high resolution 7T ex vivo MRI of the human cerebral cortex
Zeng, X.; Puonti, O.; Sayeed, A.; Herisse, R.; Mora, J.; Evancic, K.; Varadarajan, D.; Balbastre, Y.; Costantini, I.; Scardigli, M.; Ramazzotti, J.; DiMeo, D.; Mazzamuto, G.; Pesce, L.; Brady, N.; Cheli, F.; Pavone, F. S.; Hof, P. R.; Frost, R.; Augustinack, J.; van der Kouwe, A.; Iglesias, J. E.; Fischl, B.
10.1101/2023.12.06.570416 — neuroscience — Posted on 2023-12-08
3414 CELSR3 deficiency leads to tic-related behaviors and dopaminergic alterations in the striatum
Cadeddu, R.; Braccagni, G.; Musci, T.; Piras, I. S.; Anderson, C. J.; Capecchi, M. R.; Huentelman, M. J.; Moos, P. J.; Bortolato, M.
10.1101/2023.12.07.570669 — neuroscience — Posted on 2023-12-08
3415 Speech-induced suppression and vocal feedback sensitivity in human cortex
Ozker, M.; Yu, L.; Dugan, P.; Doyle, W.; Friedman, D.; Devinsky, O.; Flinker, A.
10.1101/2023.12.08.570736 — neuroscience — Posted on 2023-12-08
3416 Contextual and Combinatorial Structure in Sperm Whale Vocalisations
Sharma, P.; Gero, S.; Payne, R.; Gruber, D.; Rus, D.; Torralba, A.; Andreas, J.
10.1101/2023.12.06.570484 — animal behavior and cognition — Posted on 2023-12-08
3418 Selective lipid recruitment by an archaeal DPANN symbiont from its host
Ding, S.; Hamm, J. N.; Bale, N. J.; Sinninghe Damste, J. S.; Spang, A.
10.1101/2023.12.06.570485 — microbiology — Posted on 2023-12-08
3420 dFLASH; dual FLuorescent transcription factor Activity Sensor for Histone integrated live-cell reporting and high-content screening
Allen, T. P.; Roennfeldt, A. E.; Reckdharajkumar, M.; Liu, M.; Quinn, R.; Russell, D. L.; Peet, D. J.; Whitelaw, M. L.; Bersten, D. C.
10.1101/2023.11.21.568191 — synthetic biology — Posted on 2023-12-08
3421 A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation
Ge, A. Y.; Arab, A.; Dai, R.; Navickas, A.; Fish, L.; Garcia, K.; Asgharian, H.; Keenan, K.; Pappalardi, M. B.; McCabe, M. T.; Przybyla, L.; Goodarzi, H.; Gilbert, L.
10.1101/2022.12.14.518457 — cancer biology — Posted on 2023-12-07
3422 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment
Mukherjee, A. K.; Dutta, S.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Chatterjee, M.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; anand, V.; Perwez, A.; George, N.; Faruq, M.; Gupta, I.; Sabarinathan, R.; Chowdhury, S.
10.1101/2021.12.07.471419 — cancer biology — Posted on 2023-12-07
3423 AtERF60, negatively regulates ABR1 to modulate basal resistance response in Arabidopsis
Joshi, A.; Phukan, U. J.; Singh, N.; Jeena, G. S.; Kumar, S.; Pandey, D. K.; Pandey, A.; Tripathi, V.; Shukla, R.
10.1101/2021.12.29.474403 — plant biology — Posted on 2023-12-07
3426 Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses
Currie, J.; Manda, V.; Robinson, S. K.; Lai, C.; Agnihotri, V.; Hidalgo, V.; Ludwig, R. W.; Zhang, K.; Wang, Z. V.; Rhee, J.-W.; Lam, M. P. Y.; Lau, E.
10.1101/2023.01.04.521821 — cell biology — Posted on 2023-12-07
3427 Selective lipid recruitment by an archaeal DPANN symbiont from its host
Ding, S.; Hamm, J. N.; Bale, N. J.; Sinninghe Damste, J. S.; Spang, A.
10.1101/2023.12.06.570485 — microbiology — Posted on 2023-12-07
3428 behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments
Bowler, J. C.; Zakka, G.; Yong, H. C.; Li, W.; Rao, B.; Liao, Z.; Priestley, J. B.; Losonczy, A.
10.1101/2023.12.04.569989 — neuroscience — Posted on 2023-12-07
3429 Anatomically distributed neural representations of instincts in the hypothalamus
Stagkourakis, S.; Spigolon, G.; Marks, M.; Feyder, M.; Kim, J.; Perona, P.; Pachitariu, M.; Anderson, D. J.
10.1101/2023.11.21.568163 — neuroscience — Posted on 2023-12-07
3430 Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
Currie, M.; Davies, J.; Scalise, M.; Gulati, A.; Wright, J.; Newton-Vesty, M.; Abeysekera, G.; Subramanian, R.; Wahlgren, W.; Friemann, R.; Allison, J.; Mace, P.; Griffin, M.; Demeler, B.; Wakatsuki, S.; Drew, D.; Indiveri, C.; Dobson, R.; North, R.
10.1101/2023.08.28.549404 — biochemistry — Posted on 2023-12-07
3431 Accurate and sensitive mutational signature analysis with MuSiCal
Jin, H.; Gulhan, D. C.; Geiger, B.; Ben-Isvy, D.; Geng, D.; Ljungstrom, V.; Park, P. J.
10.1101/2022.04.21.489082 — genomics — Posted on 2023-12-07
3435 The Molecular Logic of Gtr1/2 and Pib2 Dependent TORC1 Regulation in Budding Yeast
Cecil, J. H.; Padilla, C. M.; Lipinski, A. A.; Langlais, P.; Luo, X.; Capaldi, A. P.
10.1101/2023.12.06.570342 — molecular biology — Posted on 2023-12-07
3437 Golgi-associated retrograde protein (GARP) complex recruits retromer to trans-Golgi network for FgKex2 and FgSnc1 recycling, necessary for development and pathogenicity of Fusarium graminearum
Long, Y.; Chen, X.; Chen, J.; Zhang, H.; Lin, Y.; Cheng, S.; Pu, N.; Zhou, X.; Sheng, R.; Abubakar, Y. S.; Zheng, H.; Yun, Y.; Lu, G.; Wang, Z.; Zheng, W.
10.1101/2023.12.07.570498 — microbiology — Posted on 2023-12-07
3438 Bottom-up parameterization of enzyme rate constants: Reconciling inconsistent data
Zielinski, D.; Matos, M. R. A.; de Bree, J. E.; Glass, K.; Sonnenschein, N.; Palsson, B. O.
10.1101/2023.12.05.570215 — systems biology — Posted on 2023-12-07
3441 Dietary restriction of individual amino acids stimulates unique molecular responses in mouse liver
Haws, S.; Liu, Y.; Green, C.; Babygirija, R.; Armstrong, E.; Mehendale, A.; Lamming, D.; Denu, J. M.
10.1101/2023.12.06.570456 — biochemistry — Posted on 2023-12-07
3443 Structural Basis of μ-Opioid Receptor-Targeting by a Nanobody Antagonist
Yu, J.; Kumar, A.; Zhang, X.; Martin, C.; Raia, P.; Kohl, A.; Laeremans, T.; Steyaert, J.; Manglik, A.; Ballet, S.; Boland, A.; Stoeber, M.
10.1101/2023.12.06.570395 — molecular biology — Posted on 2023-12-07
3444 In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-line-associated mitigator of isoproterenol-induced cardiac injury
Guo, C.; Jardin, B. D.; Lin, J.; Ambroise, R. L.; Wang, Z.; Yang, L.; Mazumdar, N.; Lu, F.; Ma, Q.; Cao, Y.; Liu, C.; Liu, X.; Lan, F.; Zhao, M.; Xiao, H.; Dong, E.; Pu, W. T.; Guo, Y.
10.1101/2023.12.06.570334 — molecular biology — Posted on 2023-12-07
3446 Rapid dexamethasone treatment inhibits LPS-induced cytokine storm in mice
Zhang, F.; Xiao, L.; Li, Y.; Feng, R.; Zhou, M.; Tang, S.; Liebe, R.; Ebert, M. P.; Dooley, S.; Li, L.; Weng, H.
10.1101/2023.12.07.570372 — molecular biology — Posted on 2023-12-07
3448 The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures
Passchier, T. C.; White, J. B. R.; Maskell, D. P.; Byrne, M. J.; Ranson, N. A.; edwards, t. a.; Barr, J. N.
10.1101/2023.12.07.570572 — microbiology — Posted on 2023-12-07
3451 Single Amplified Genome Catalog Reveals the Dynamics of Mobilome and Resistome in the Human Microbiome
Kawano-Sugaya, T.; Arikawa, K.; Saeki, T.; Endoh, T.; Kamata, K.; Matsuhashi, A.; Hosokawa, M.
10.1101/2023.12.06.570492 — microbiology — Posted on 2023-12-07
3453 Selective lipid recruitment by an archaeal DPANN symbiont from its host
Ding, S.; Hamm, J. N.; Bale, N. J.; Sinninghe Damste, J. S.; Spang, A.
10.1101/2023.12.06.570485 — microbiology — Posted on 2023-12-07
3454 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a Partial STING Agonist, Competes for Human STING Activation
Temizoz, B.; Shibahara, T.; Hioki, K.; Hayashi, T.; Kobiyama, K.; Lee, M. S. J.; Surucu, N.; Sag, E.; Kumanogoh, A.; Yamamoto, M.; Gursel, M.; Ozen, S.; Kuroda, E.; Coban, C.; Ishii, K. J.
10.1101/2023.12.07.570548 — immunology — Posted on 2023-12-07
3455 PHEIGES, all-cell-free phage synthesis and selection from engineered genomes
Levrier, A.; Karpathakis, I.; Nash, B.; Bowden, S. D.; Lindner, A. B.; Noireaux, V.
10.1101/2023.12.07.570578 — synthetic biology — Posted on 2023-12-07
3458 Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma
Thoppey Manoharan, V.; Abdelkareem, A.; Brown, S.; Gillmor, A.; Hall, C.; Seo, H.; Narta, K.; Grewal, S.; Dang, N. H.; Ahn, B. Y.; Otz, K.; Lun, X.; Mah, L.; Zemp, F. J.; Mahoney, D. J.; Senger, D. L.; Chan, J. A.; Morrissy, S.
10.1101/2023.12.05.570149 — cancer biology — Posted on 2023-12-07
3459 Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation.
Li, F.; Gallego, J.; Tirko, N. N.; Greaser, J.; Bashe, D.; Patel, R.; Shaker, E.; Van Valkenburg, G. E.; Alsubhi, A. S.; Wellman, S.; Singh, V.; Garcia Padill, C.; Gheres, K. W.; Bagwell, R.; Mulvihill, M.; Kozai, T. D. Y.
10.1101/2023.12.05.570162 — bioengineering — Posted on 2023-12-07
3460 Automation of Experimental Workflows for High Throughput Robotic Cultivations
Kaspersetz, L.; Schroeder-Kleeberg, F.; Mione, F. M.; Martinez, E. C.; Neubauer, P.; Cruz-Bournazou, M. N.
10.1101/2023.12.05.570077 — bioengineering — Posted on 2023-12-07
3461 FITM2 deficiency results in ER lipid accumulation, ER stress, reduced apolipoprotein B lipidation, and VLDL triglyceride secretion in vitro and in mouse liver
Wang, H.; Nikain, C.; Amengual, J.; La Forest, M.; Yu, Y.; Wang, M. C.; Watts, R.; Lehner, R.; Qiu, Y.; Cai, M.; Kurland, I. J.; Goldberg, I. J.; Rajan, S.; Hussain, M. M.; Brodsky, J. L.; Fisher, E. A.
10.1101/2023.12.05.570183 — biochemistry — Posted on 2023-12-07
3464 Predicting the Purity of Multispecific Antibodies From Sequence Using Machine Learning: Methods and Applications
Mazurek, A. S.; Davis, A.; Tsang, K.; Rivera, J.; Huang, Z.-F.; Holt, J.; Comeau, S. R.; Kumar, S.; Kasturirangan, S.
10.1101/2023.12.05.570217 — molecular biology — Posted on 2023-12-07
3465 CRISPR-HOLMES-based NAD+ detection
Zhuang, S.; Hu, T.; Zhou, H.; He, S.; Li, J.; Zhang, Y.; Gu, D.; Xu, Y.; Chen, Y.; Wang, J.
10.1101/2023.12.06.570494 — molecular biology — Posted on 2023-12-07
3466 Tight junction component protein claudin-1 deficiency in retinal pigment epithelium leads to early and intermediate age-related macular degeneration phenotypes in mice.
Nakai, A.; Lee, D.; Zhang, Y.; Shoda, C.; Imanishi, S.; Jeong, H.; Ikeda, S.-i.; Negishi, K.; Nakashizuka, H.; Yamagami, S.; Kubo, A.; Kurihara, T.
10.1101/2023.12.07.570525 — molecular biology — Posted on 2023-12-07
3470 Heterogeneous lineage-specific arginine deiminase expression within dental microbiome species
Mann, A. E.; Chakraborty, B.; O'Connell, L. M.; Nascimento, M. M.; Burne, R. A.; Richards, V. P.
10.1101/2023.12.07.570591 — microbiology — Posted on 2023-12-07
3473 Changes in ADAR1 activity during Plasmodium infection contribute to protection from malaria.
Quin, J. E.; Kopel, E.; Gawish, R.; Eidelman, M.; Vukic, D.; Linhartova, P.; Melicherova, J.; Sinigaglia, K.; Ghodrati, S.; Arama, C.; Nebie, I.; Troye-Blomberg, M.; Sverremark-Ekström, E.; Knapp, S.; Modry, D.; Farrants, A.-K. O.; Levanon, E.; Keegan, L. P.; O'Connell, M. A.
10.1101/2023.12.07.570604 — immunology — Posted on 2023-12-07
3474 Rapid TetOn-mediated gene expression in neuronsacross the lifespan using uTTOP
Salmon, C. K.; Quesseveur, G.; Cheong, G. H. L.; Chierzi, S.; Rosen, M. P.; Green, M.; Gao, A. Y. L.; Kacerovsky, J. B.; Murai, K. K.
10.1101/2023.12.05.570307 — neuroscience — Posted on 2023-12-07
3475 Beyond Active Learning: Using 3-Dimensional Learning to Create Scientifically Authentic, Student-Centered Classrooms
Cooper, M. M.; Caballero, M. D.; Carmel, J. H.; Duffy, E. M.; Fata-Hartley, C. L.; Herrington, D. G.; Nelson, P. C.; Laverty, J. T.; Posey, L. A.; Stoltzfus, J. R.; Stowe, R. L.; Sweeder, R. D.; Tessmer, S.; Underwood, S. M.; Ebert-May, D.
10.1101/2023.12.05.570209 — scientific communication and education — Posted on 2023-12-07
3477 Targeting NGF but not VEGF or BDNF signaling reduces endometriosis-associated pain in mice
Zaninelli, T. H.; Fattori, V.; Heintz, O. K.; Wright, K. R.; Bennallack, P. R.; Sim, D.; Bukhari, H.; Terry, K. L.; Vitonis, A. F.; Missmer, S. A.; Andrello, A. C.; Anchan, R.; Godin, S. K.; Bree, D.; Verri, W. A.; Rogers, M. S.
10.1101/2023.12.05.570181 — pharmacology and toxicology — Posted on 2023-12-07
3478 Development of pre-clinical murine models for fibrolamellar hepatocellular carcinoma
He, A.; Coles, G. L.; Hartmann, G. H.; Le, V.; Mauch, B.; Xu, L.; Nguyen, T.; Hazard, F. K.; Sage, J.
10.1101/2023.12.06.569624 — cancer biology — Posted on 2023-12-07
3482 A "through-DNA" mechanism for metal uptake-vs.-efflux regulation
Chakraborty, U. K.; Park, Y.; Sengupta, K.; Jung, W.; Joshi, C.; Francis, D. H.; Chen, P.
10.1101/2023.12.05.570191 — biophysics — Posted on 2023-12-07
3487 In Silico Therapeutic Intervention on Cytokine Storm in COVID-19
Bakshi, A.; Gangopadhyay, K.; Basak, S.; Chakrabarti, A.; Dasgupta, A.; De, R. K.
10.1101/2023.12.05.570280 — bioinformatics — Posted on 2023-12-07
3490 Improving population scale statistical phasing with whole-genome sequencing data
Wertenbroek, R.; Hofmeister, R.; Xenarios, I.; Thoma, Y.; Delaneau, O.
10.1101/2023.12.07.570528 — genomics — Posted on 2023-12-07
3496 Can upwelling regions be potential thermal refugia for marine species during climate warming? The case of Mexico
Angeles-Gonzalez, L. E.; Torrejon-Magallanes, J.; Osorio-Olvera, L.; Avendano, O.; Diaz, F.; Rosas, C.
10.1101/2023.12.05.570267 — ecology — Posted on 2023-12-07
3497 Advancing bee conservation in the US: gaps and opportunities in data collection and reporting
Rousseau, J. S.; Woodard, S. H.; Jepsen, S.; Du Clos, B.; Johnston, A.; Danforth, B. N.; Rodewald, A. D.
10.1101/2023.12.05.569280 — ecology — Posted on 2023-12-07
3499 Using Unstructured Crowd-sourced Data to Evaluate Urban Tolerance of Terrestrial Native Species within a California Mega-City
Curti, J. N.; Barton, M.; Flores, R. G.; Lechner, M.; Lipman, A. J.; Montgomery, G. A.; Park, A. Y.; Rochel, K.; Tingley, M. W.
10.1101/2023.12.05.570260 — ecology — Posted on 2023-12-07
3501 Axon guidance genes are regulated by TDP-43 and RGNEF through the rate of long-intron processing.
Buratti, E.; Abbassi, Y.; Cappelli, S.; Spagnolo, E.; Gennari, A.; Visani, G.; Barattucci, S.; Paron, F.; Stuani, C.; Droppelmann, C.; Strong, M. J.
10.1101/2023.12.05.570131 — neuroscience — Posted on 2023-12-07
3504 Cognitive load dissonance and personality factors: an empirical analysis in organizational settings
Di Gruttola, F.; Mastrogiorgio, A.; Orfei, M. D.; D'Arcangelo, S.; Lattanzi, N.; Ricciardi, E.; Malizia, A. P.
10.1101/2023.12.05.570254 — neuroscience — Posted on 2023-12-07
3505 Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents
Dahir, N. S.; Gui, Y.; Wu, Y.; Sweeney, P. R.; Williams, S. Y.; Gimenez, L. E.; Sawyer, T. K.; Joy, S. T.; Mapp, A. K.; Cone, R. D.
10.1101/2023.12.05.570114 — neuroscience — Posted on 2023-12-07
3507 Statistical diversity distinguishes global states of consciousness
Starkey, J.; Carhart-Harris, R.; Pigorini, A.; Nobili, L.; Barrett, A.
10.1101/2023.12.05.570101 — neuroscience — Posted on 2023-12-07
3508 Multilayer meta-matching: translating phenotypic prediction models from multiple datasets to small data
Chen, P.; An, L.; Wulan, N.; Zhang, C.; Zhang, S.; Ooi, L. Q. R.; Kong, R.; Chen, J.; Wu, J.; Chopra, S.; Bzdok, D.; Eickhoff, S. B.; Holmes, A.; Yeo, B. T. T.
10.1101/2023.12.05.569848 — neuroscience — Posted on 2023-12-07
3509 Sord deficient rats develop a motor-predominant peripheral neuropathy unveiling novel pathophysiological insights
Rebelo, A.; Abad, C.; Dohrn, M. F.; Li, J. J.; Tieu, E.; Medina, J.; Yanick, C.; Huang, J.; Zotter, B.; Young, J. I.; Saporta, M.; Scherer, S. S.; Walz, K.; Zuchner, S.
10.1101/2023.12.05.570001 — neuroscience — Posted on 2023-12-07
3510 Neural correlates of category learning in monkey inferior temporal cortex
Pearl, J. E.; Matsumoto, N.; Hayashi, K.; Matsuda, K.; Nagai, Y.; Miyakawa, N.; Minamimoto, T.; Saunders, R. C.; Sugase-Miyamoto, Y.; Richmond, B. J.; Eldridge, M. A. G.
10.1101/2023.12.05.568765 — neuroscience — Posted on 2023-12-07
3512 Neuronal connectivity, behavioral, and transcriptional alterations associated with the loss of MARK2
Caiola, H. O.; Wu, Q.; Soni, S.; Wang, X.-F.; Monahan, K.; Pang, Z. P.; Wagner, G. C.; Zhang, H.
10.1101/2023.12.05.569759 — neuroscience — Posted on 2023-12-07
3513 The Effects of Physical and Mental Fatigue on Time Perception
Goudini, R. G.; Zahiri, A.; Alizadeh, S.; Drury, B.; Hadjizadeh Anvar, S.; Daneshjoo, A.; Behm, D. G.
10.1101/2023.12.05.570265 — neuroscience — Posted on 2023-12-07
3514 Sex-specific role for the long noncoding RNA Pnky in mouse behavior
Saha, P.; Andersen, R. E.; Hong, S. J.; Gil, E.; Simms, J.; Lim, D. A.
10.1101/2023.12.05.569777 — neuroscience — Posted on 2023-12-07
3515 Agonists of melatonin receptors strongly promote the functional recovery from the neuroparalysis induced by neurotoxic snakes
D'este, G.; Fabris, F.; Stazi, M.; Baggio, C.; Simonato, M.; Megighian, A.; Rigoni, M.; Negro, S.; Montecucco, C.
10.1101/2023.12.05.570230 — pharmacology and toxicology — Posted on 2023-12-07
3516 Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging
Kirchgaessner, R.; Watson, C.; Creason, A. L.; Keutler, K.; Goecks, J.
10.1101/2023.12.05.570058 — cancer biology — Posted on 2023-12-07
3521 Privacy-preserving impact evaluation using Differences-in-Differences
Huth, M.; Alvarez Garavito, C.; Cirera, L.; Sicuri, E.; Hasenauer, J.
10.1101/2023.12.05.570107 — bioinformatics — Posted on 2023-12-07
3526 Inferring Metabolic States from Single Cell Transcriptomic Data via Geometric Deep Learning
Steach, H. R.; Viswanath, S.; He, Y.; Zhang, X.; Ivanova, N.; Hirn, M.; Perlmutter, M.; Krishnaswamy, S.
10.1101/2023.12.05.570153 — bioinformatics — Posted on 2023-12-07
3527 Noninvasive Injectable Optical Nanosensor-Hydrogel Hybrids Detect Doxorubicin in Living Mice
Cohen, Z.; Alpert, D. J.; Weisel, A. C.; Roach, A.; Rahman, S.; Gaikwad, P. V.; Nicoll, S. B.; Williams, R. M.
10.1101/2023.12.05.570137 — bioengineering — Posted on 2023-12-07
3530 Highly Multiplexed Fluorescence Microscopy with Spectrally Tunable Semiconducting Polymer Dots
Guo, Z.; Poudel, C.; Yu, J.; Wong, M.; Sarfatis, M. C.; Chiu, D. T.; Vaughan, J. C.
10.1101/2023.12.05.570289 — biochemistry — Posted on 2023-12-07
3532 AhR ligands from LGG metabolites promote piglet intestinal ILC3 activation and IL-22 secretion to inhibit PEDV infection
Wang, J.; Zhao, Y.; Cui, T.; Bao, H.; Gao, M.; Cheng, M.; Sun, Y.; Lu, Y.; Guan, J.; Zhang, D.; Jiang, Y.; Huang, H.; Shi, C.; Wang, J.; Wang, N.; Hu, J.; Yang, W.; Yang, G.; Zeng, Y.; Wang, C.; Cao, X.
10.1101/2023.12.05.570065 — immunology — Posted on 2023-12-07
3533 Aversive memories can be weakened during human sleepvia the reactivation of positive interfering memories
Xia, T.; Chen, D.; Zeng, S.; Yao, Z.; Liu, J.; Qin, S.; Paller, K. A.; Torres-Platas, S. G.; Antony, J. W.; Hu, X.
10.1101/2023.12.05.570072 — neuroscience — Posted on 2023-12-07
3534 Cue-Invariant Geometric Structure of the Population Codes in Macaque V1 and V2
Massot, C.; Zhang, X.; Wang, Z.; Rockwell, H.; Papandreou, G.; Yuille, A.; Lee, T.-S.
10.1101/2023.12.05.570110 — neuroscience — Posted on 2023-12-07
3537 Signalling-state dependent drug-tolerance in head and neck squamous cell carcinoma.
Karjosukarso, D. W.; Dini, A.; Wingens, L. J. A.; Liu, R.; Joosten, L. A. B.; Bussink, J.; Mulder, K. W.
10.1101/2023.12.05.570063 — systems biology — Posted on 2023-12-07
3539 Key phosphorylation sites for robust β-arrestin2 binding at the mu-opioid receptor revisited
Underwood, O.; Frizwanker, S.; Glenn, J.; Batista-Gondin, A.; Drube, J.; Hoffmann, C.; Briddon, S. J.; Schulz, S. S.; Canals, M.
10.1101/2023.12.05.570073 — pharmacology and toxicology — Posted on 2023-12-07
3540 Dystrophin deficiency impairs cell junction formation during embryonic myogenesis
Mozin, E.; Massourides, E.; Mournetas, V.; Lievre, C.; Bourdon, A.; Jackson, D. L.; Packer, J. S.; Trapnell, C.; Le Guiner, C.; Adjali, O.; Pinset, C.; Mack, D. L.; Dupont, J.-B.
10.1101/2023.12.05.569919 — pathology — Posted on 2023-12-07
3542 Natural disaster alters the adaptive benefits of sociality in a primate
Testard, C.; Shergold, C.; Acevedo-Ithier, A.; Hart, J.; Negron-Del Valle, J.; Philips, D.; Watowich, M.; Sanguinetti-Scheck, J. I.; Montague, M.; Snyder-Mackler, N. J.; Higham, J.; Platt, M.; Brent, L. J.
10.1101/2023.07.17.549328 — animal behavior and cognition — Posted on 2023-12-07
3544 Structure, interaction, and nervous connectivity of beta cell primary cilia
Müller, A.; Klena, N.; Pang, S.; Garcia, L. E. G.; Sulaymankhil, D.; Topcheva, O.; Seliskar, M.; Mziaut, H.; Schöniger, E.; Friedland, D.; Kipke, N.; Kretschmar, S.; Münster, C.; Weitz, J.; Distler, M.; Kurth, T.; Schmidt, D.; Hess, H. F.; Xu, C. S.; Pigino, G.; Solimena, M.
10.1101/2023.12.01.568979 — cell biology — Posted on 2023-12-07
3545 Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease
Levites, Y.; Dammer, E. B.; Ran, Y.; Tsering, W.; Duong, D.; Abreha, M.; Gadhavi, J.; Lolo, K.; Trejo-Lopez, J.; Phillips, J. L.; Iturbe, A.; Erqiuzi, A.; Moore, B. D.; Ryu, D.; Natu, A.; Dillon, K. D.; Torrellas, J.; Moran, C.; Ladd, T. B.; Afroz, K. F.; Islam, T.; Jagirdar, J.; Funk, C. C.; Robinson, M.; Borchelt, D. R.; Ertekin-Taner, N.; Kelly, J. W.; Heppner, F. L.; Johnson, E. C.; McFarland, K.; Levey, A. L.; Prokop, S.; Seyfried, N. T.; Golde, T. E.
10.1101/2023.11.29.568318 — neuroscience — Posted on 2023-12-07
3546 Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus
Wilmot, J. H.; Diniz, C. R. A. F.; Crestani, A. P.; Puhger, K.; Roshgadol, J.; Tian, L.; Wiltgen, B. J.
10.1101/2022.10.17.512590 — neuroscience — Posted on 2023-12-07
3547 AKAP150-anchored PKA regulation of synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the lateral habenula
Simmons, S. C.; Ferlage, W. J.; Langlois, L. D.; Shepard, R. D.; Bouslog, C.; Thomas, E. H.; Gouty, K. M.; SANDERSON, J. L.; Gouty, S.; Cox, B. M.; Dell'Acqua, M. L.; Nugent, F. S.
10.1101/2023.12.06.570160 — neuroscience — Posted on 2023-12-07
3548 Aging and intraocular pressure homeostasis in mice
Li, G.; van Batenburg-Sherwood, J.; Safa, B. N.; Fraticelli Guzman, N. S.; Wilson, A.; Bahrani Fard, M. R.; Choy, K.; de Ieso, M. L.; Cui, S.; Feola, A. J.; Weisz, T.; Kuhn, M.; Bowes Rickman, C.; Farsiu, S.; Ethier, C. R.; Stamer, W. D.
10.1101/2023.10.17.562768 — physiology — Posted on 2023-12-07
3556 RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages
Susanto, T. T.; Hung, V.; Levine, A. G.; Kerr, C. H.; Yoo, Y.; Chen, Y.; Oses-Prieto, J. A.; Fromm, L.; Fujii, K.; Wernig, M.; Burlingame, A.; Ruggero, D.; Barna, M.
10.1101/2023.12.07.570613 — molecular biology — Posted on 2023-12-07
3559 The vestibulospinal nucleus is a locus of balance development
Hamling, K. R.; Harmon, K.; Kimura, Y.; Higashijima, S.-i.; Schoppik, D.
10.1101/2023.12.06.570482 — neuroscience — Posted on 2023-12-07
3560 Inferring genetic structure of European beech from observations of spectral phenotypes
Czyz, E. A.; Schmid, B.; Eppinga, M. B.; de La Harpe, M.; Moradi, A.; Li, C.; Schaepman, M. E.; Schuman, M. C.
10.1101/2023.08.16.553487 — plant biology — Posted on 2023-12-07
3562 Low-cost 3D printed lenses for brightfield and fluorescence microscopy
Christopher, J.; Rooney, L. M.; Donnachie, M.; Uttamchandani, D.; McConnell, G.; Bauer, R.
10.1101/2023.11.22.568227 — biophysics — Posted on 2023-12-07
3563 The genome regulatory landscape of Atlantic salmon liver through smoltification
Harvey, T.; Gillard, G. B.; Rosaeg, L. L.; Grammes, F.; Monsen, O.; Vik, J. O.; Hvidsten, T. R.; Sandve, S. R.
10.1101/2023.08.16.553484 — genomics — Posted on 2023-12-07
3565 Levetiracetam Modulates Brain Metabolic Networks and Transcriptomic Signatures in the 5XFAD Mouse Model of Alzheimer's disease.
Burton, C. P.; Chumin, E. J.; Collins, A. Y.; Pandey, R. S.; Persohn, S. A.; Quinney, S. K.; Pandey, R. S.; Onos, K. D.; Territo, P. R.
10.1101/2023.11.10.566574 — neuroscience — Posted on 2023-12-07
3566 Axonopathy and altered synaptic development in early hippocampal epileptogenesis of Dravet syndrome
Layer, N.; Müller, P.; Ayash, M.; Pfeiffer, F.; Saile, M.; Klopfer, F.; Iavarone, S.; Santuy, A.; Fallier-Becker, P.; Hedrich, U. B. S.; Lerche, H.; Koch, H.; Wuttke, T. V.
10.1101/2023.10.04.560735 — neuroscience — Posted on 2023-12-07
3570 Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers
Xie, Y.; Ruan, F.; Li, Y.; Luo, M.; Zhang, C.; Chen, Z.; Xie, Z.; Weng, Z.; Chen, W.; Chen, W.; Fang, Y.; Sun, Y.; Guo, M.; Wang, J.; Xu, S.; Wang, H.; Tang, C.
10.1101/2022.04.21.489011 — genomics — Posted on 2023-12-07
3573 Design of a Biohybrid Materials Circuit with Binary Decoder Functionality
Mohsenin, H.; Wagner, H.; Rosenblatt, M.; Kemmer, S.; Drepper, F.; Huesgen, P.; Timmer, J.; Weber, W.
10.1101/2023.08.10.552766 — synthetic biology — Posted on 2023-12-07
3574 How osteons form: A quantitative hypothesis-testing analysis of cortical pore filling and wall asymmetry
Hegarty-Cremer, S. G.; Borggaard, X. G.; Andreasen, C. M.; van der Eerden, B. C.; Simpson, M. J.; Andersen, T. L.; Buenzli, P. R.
10.1101/2023.10.26.564273 — biophysics — Posted on 2023-12-07
3578 RERconverge Expansion: Using Relative Evolutionary Rates to Study Complex Categorical Trait Evolution
Redlich, R. W.; Kowalczyk, A.; Tene, M.; Sestili, H. H.; Foley, K.; Saputra, E.; Clark, N.; Chikina, M.; Meyer, W. K.; Pfenning, A.
10.1101/2023.12.06.570425 — bioinformatics — Posted on 2023-12-07
3581 A potential pathway that links intron retention with the physiological recovery by a Japanese herbal medicine
Okada, N.; Oshima, K.; Maruko, A.; Vu, T.-D.; Chiu, M.-T.; Nishiyama, M.; Yamamoto, M.; Nishi, A.; Kobayashi, Y.
10.1101/2023.12.02.569734 — bioinformatics — Posted on 2023-12-07
3583 Expanded Expression of Pro-Neurogenic Factor SoxB1 during Larval Development of Gastropod Lymnaea stagnalis Suggests Preadaptation to Prolonged Neurogenesis in Mollusca
Kurtova, A. I.; Finoshin, A. D.; Aparina, M. S.; Gazizova, G. R.; Kozlova, O. S.; Voronova, S. N.; Shagimardanova, E. I.; Voronezhskaya, E. E.; Ivashkin, E. G.
10.1101/2023.11.29.569209 — developmental biology — Posted on 2023-12-07
3584 Sleep consolidation potentiates skill maintenance
Solano, A.; Lerner, G.; Griffa, G.; Deleglise, A.; Caffaro, P.; Riquelme, L.; Perez-Chada, D.; Della-Maggiore, V.
10.1101/2023.10.26.564031 — neuroscience — Posted on 2023-12-07
3586 Digging deeper into pain - an ethological behavior assay correlating well-being in mice with human pain experience.
Pattison, L. A.; Cloake, A.; Chakrabarti, S.; Hilton, H.; Rickman, R. H.; Higham, J. P.; Meng, M. Y.; Paine, L. W.; Dannawi, M.; Qiu, L.; Ritoux, A.; Bulmer, D. C.; Callejo, G.; Smith, E. S. J.
10.1101/2023.08.18.553862 — neuroscience — Posted on 2023-12-07
3587 External Cues Improve Visual Working Memory Encoding in the Presence of Salient Distractors in Schizophrenia
Barnes-Scheufler, C. V.; Roesler, L.; Schaum, M.; Schiweck, C.; Peters, B.; Reif, A.; Wibral, M.; Bittner, R. A.
10.1101/2021.05.19.442954 — neuroscience — Posted on 2023-12-07
3588 Synapsin E-domain is essential for α-synuclein function
Stavsky, A.; Parra-Rivas, L. A.; Tal, S.; Riba, J.; Madhivanan, K.; Roy, S.; Gitler, D.
10.1101/2023.06.24.546170 — neuroscience — Posted on 2023-12-07
3592 Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries
Weile, J.; Ferra, G.; Boyle, G.; Pendyala, S.; Amorosi, C.; Yeh, C.-L.; Cote, A. G.; Kishore, N.; Tabet, D.; van Loggerenberg, W.; Rayhan, A.; Fowler, D. M.; Dunham, M. J.; Roth, F. P.
10.1101/2023.02.22.529427 — bioinformatics — Posted on 2023-12-07
3593 Analysis of NIH K99/R00 Awards and the Career Progression of Awardees
Woitowich, N. C.; Hengel, S. R.; Solis, C.; Vilgalys, T. P.; Babdor, J.; Tyrrell, D. J.
10.1101/2023.01.26.525751 — scientific communication and education — Posted on 2023-12-07
3594 Maximizing the potential of genomic and transcriptomic studies by nanopore sequencing
Meyer, D.; Goettsch, W.; Spangenberg, J.; Bohn, P.; Stieber, B.; Krautwurst, S.; Hoener zu Siederdissen, C.; Srivastava, A.; Zarkovic, M.; Wollny, D.; Marz, M.
10.1101/2023.12.06.570356 — bioinformatics — Posted on 2023-12-07
3597 G1 length dictates heterochromatin landscape
Trouth, A.; Ravichandran, K.; Gafken, P.; Martire, S.; Namciu, S. J.; Banaszynski, L. A.; Sarthy, J. F.; Ramachandran, S.
10.1101/2023.12.05.570186 — molecular biology — Posted on 2023-12-07
3598 SARS-CoV-2 NSP5 Antagonizes MHC II Expression by Subverting Histone Deacetylase 2
Taefehshokr, N.; Lac, A.; Vrieze, A. M.; Dickson, B. H.; Guo, P. N.; Jung, C.; Blythe, E. N.; Fink, C.; Aktar, A.; Dikeakos, J. D.; Dekaban, G. A.; Heit, B.
10.1101/2023.02.10.528032 — immunology — Posted on 2023-12-07
3602 Mapping memories: pulse-chase labeling reveals AMPA receptor dynamics during memory formation
Kim, D.; Park, P.; Li, X. T.; Wong-Campos, J. D.; Tian, H.; Moult, E. M.; Grimm, J. B.; Lavis, L.; Cohen, A. E.
10.1101/2023.05.26.541296 — neuroscience — Posted on 2023-12-07
3603 Disease progression modelling reveals heterogeneity in trajectories of Lewy-type alpha-synuclein pathology
Mastenbroek, S. E.; Vogel, J. W.; Collij, L. E.; Serrano, G. E.; Tremblay, C.; Young, A. L.; Arce, R. A.; Shill, H. A.; Driver-Dunckley, E. D.; Mehta, S. H.; Belden, C. M.; Atri, A.; Choudhury, P.; Barkhof, F.; Adler, C. H.; Ossenkoppele, R.; Beach, T. G.; Hansson, O.
10.1101/2023.12.05.569878 — pathology — Posted on 2023-12-07
3606 Post-GWAS Prioritization of Genome-Phenome Associations in Sorghum
Pal, D.; Schaper, K.; Thompson, A.; Guo, J.; Jaiswal, P.; Lisle, C.; Cooper, L.; LeBauer, D.; Thessen, A.; Ross, A.
10.1101/2023.12.05.570238 — genomics — Posted on 2023-12-07
3607 The black honey bee genome: insights on specific structural elements and a first step towards pan-genomes
Eynard, S. E.; Klopp, C.; Canale-Tabet, K.; Marande, W.; Vandecasteele, C.; Lopez-Roques, C.; Boone, Q.; Donnadieu, C.; Servin, B.; Vignal, A.
10.1101/2023.12.06.570386 — genomics — Posted on 2023-12-07
3609 Breakdown and repair of the aging brain metabolic system
Shichkova, P.; Coggan, J. S.; Kanari, L.; Boci, E.; Favreau, C. P. H.; Antonel, S. M.; Keller, D.; Markram, H.
10.1101/2023.08.30.555341 — neuroscience — Posted on 2023-12-07
3615 Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues
Rebollo, R.; Gerenton, P.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.
10.1101/2023.05.27.542554 — bioinformatics — Posted on 2023-12-07
3617 ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function
Ha, K.; Loeb, G. B.; Park, M.; Pinedo, A.; Park, C. H.; Brandes, N.; Ritu, F.; Ye, C. J.; Reiter, J. F.; Delling, M.
10.1101/2023.12.04.570035 — cell biology — Posted on 2023-12-07
3618 Phage predation is a biomarker for disease severity and shapes pathogen genetic diversity in cholera patients
Madi, N.; Cato, E. T.; Sayeed, M. A.; Creasy-Marrazzo, A.; Cuenod, A.; Islam, K.; Khabir, M. I. U.; Bhuiyan, M. T. R.; Begum, Y.; Freeman, E.; Vustepalli, A.; Brinkley, L.; Rashid, M. M.; Kamat, M.; Bailey, L. S.; Basso, K. B.; Qadri, F.; Khan, A. I.; Shapiro, B. J.; Nelson, E. J.
10.1101/2023.06.14.544933 — microbiology — Posted on 2023-12-07
3623 The BTB-ZF gene Bm-mamo regulates pigmentation in silkworm caterpillars
Wu, S.; Tong, X.; Peng, C.; Luo, J.; Zhang, C.; Lu, K.; Li, C.; Ding, X.; Duan, X.; Lu, Y.; Hu, H.; Tan, D.; Dai, F.
10.1101/2023.04.07.536007 — genetics — Posted on 2023-12-07
3624 Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion
Polsani, N.; Yung, T.; Thomas, E. C.; Phung-Rojas, M.; Gupta, I.; Denker, J.; Feng, X.; Ibarra, B.; Hopyan, S.; Atit, R.
10.1101/2023.12.05.570300 — developmental biology — Posted on 2023-12-07
3625 Metrics of Coral Microfragment Viability
Lager, C.; Perry, R.; Daly, J.; Page, C.; Mizobe, M.; Bouwmeester, J.; Consiglio, A.; Carter, J.; Powell-Palm, M. J.; Hagedorn, M.
10.1101/2023.01.03.522625 — cell biology — Posted on 2023-12-07
3627 Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
Pahl, M. C.; Sharma, P.; Thomas, R. M.; Thompson, Z.; Mount, Z.; Pippin, J.; Morawski, P. A.; Su, C.; Campbell, D. J.; Grant, S. F.; WELLS, A. D.
10.1101/2023.04.05.535731 — immunology — Posted on 2023-12-07
3628 Neural correlates of confidence during decision formation in a perceptual judgment task
Ko, Y. H.; Zhou, A.; Niessen, E.; Stahl, J.; Weiss, P. H.; Hester, R.; Bode, S.; Feuerriegel, D. C.
10.1101/2023.08.13.553156 — neuroscience — Posted on 2023-12-07
3630 Accurate multi-population imputation of MICA, MICB, HLA-E, HLA-F and HLA-G alleles from genome SNP data
Tammi, S.; Koskela, S.; Blood Service Biobank, ; Hyvärinen, K.; Partanen, J.; Ritari, J.
10.1101/2023.12.05.570226 — bioinformatics — Posted on 2023-12-07
3631 Comprehensive Genomic Features indicative for Notch Responsiveness
Giaimo, B. D.; Friedrich, T.; Ferrante, F.; Bartkuhn, M.; Borggrefe, T.
10.1101/2023.12.04.569922 — genomics — Posted on 2023-12-07
3632 Transposition, duplication, and divergence of the telomerase RNA underlies the Mimulus telomere evolution
Kumawat, S.; Martinez, I.; Logeswaran, D.; Chen, H.; Coughlan, J.; Chen, J.; Yuan, Y.-w.; Sobel, J.; Choi, J. Y.
10.1101/2023.12.06.568249 — evolutionary biology — Posted on 2023-12-07
3633 Evolution of a biological thermocouple by adaptation of cytochrome c oxidase in asubterrestrial metazoan
Guerin, M. N.; Ellis, T. S.; Ware, M. J.; Manning, A.; Coley, A.; Amini, A.; Chung, G.; Gunsalus, K. C.; Bracht, J. R.
10.1101/2023.12.05.570156 — evolutionary biology — Posted on 2023-12-07
3634 Ancestral neural circuits potentiate the origin of a female sexual behavior
Li, M.; Chen, D. S.; Junker, I. P.; Szorenyi, F. I.; Chen, G. H.; Berger, A. J.; Comeault, A. A.; Matute, D. R.; Ding, Y.
10.1101/2023.12.05.570174 — evolutionary biology — Posted on 2023-12-07
3639 Enhancer cooperativity can compensate for loss of activity over large genomic distances
Thomas, H. F.; Feng, S.; Huber, M.; LOUBIERE, V.; Vanina, D.; Pitasi, M.; Stark, A.; Buecker, C.
10.1101/2023.12.06.570399 — molecular biology — Posted on 2023-12-07
3640 Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states
Ndhlovu, L.; Bendall, M.; Dwaraka, V. B.; Pang, A. P.; Dopkins, N.; Carreras, N.; Smith, R.; Nixon, D.; Corley, M. J.
10.1101/2023.12.06.570422 — immunology — Posted on 2023-12-07
3643 Evolutionary repurposing of trypanosomal Pam18 and Pam16 reveals a new regulatory circuit for mitochondrial genome replication
von Känel, C.; Oeljeklaus, S.; Calderaro, S.; Durante, I. M.; Raskova, V.; Warscheid, B.; Schneider, A.
10.1101/2023.12.05.570232 — biochemistry — Posted on 2023-12-07
3645 Paternal-effect genes revealed through semen cryopreservation in Perca fluviatilis
Panda, A.; Judycka, S.; Palinska-Zarska, K.; Debernardis, R.; Jarmolowicz, S.; Jastrzebski, J.; de Almeida, T. R.; Blazejewski, M.; Hliwa, P.; Krejszeff, S.; Zarski, D.
10.1101/2023.12.06.570413 — developmental biology — Posted on 2023-12-07
3646 Piezo mediates Rho activation and actin stress fibre formation in Drosophila nephrocytes
Schulz, K.; Edenhofer, I.; Lindenmeyer, M.; Lohr, C.; Huber, T. B.; Denholm, B.; Koehler, S.
10.1101/2021.10.23.465463 — cell biology — Posted on 2023-12-07
3648 Molecular determinants of SEC61A1 mutant R236C in two patient-derived cellular platforms
Weiand, M.; Sandfort, V.; Nadzemova, O.; Schierwagen, R.; Trebicka, J.; Kabar, I.; Schmidt, H.; Zibert, A.
10.1101/2023.12.05.570221 — cell biology — Posted on 2023-12-07
3651 Sequence-based GWAS in 180 000 German Holstein cattle reveals new candidate genes for milk production traits
Krizanac, A.-M.; Reimer, C.; Heise, J.; Liu, Z.; Pryce, J.; Bennewitz, J.; Thaller, G.; Falker-Gieske, C.; Tetens, J.
10.1101/2023.12.06.570350 — genomics — Posted on 2023-12-06
3657 Microsomal triglyceride transfer protein is necessary to maintain lipid homeostasis and retinal function
Grubaugh, C. R.; Dhingra, A.; Prakash, B.; Montenegro, D.; Sparrow, J. R.; Daniele, L. L.; Curcio, C. A.; Bell, B. A.; Hussain, M. M.; Boesze-Battaglia, K.
10.1101/2023.12.06.570418 — cell biology — Posted on 2023-12-06
3660 Functional network collapse in neurodegenerative disease
Brown, J. A.; Lee, A. J.; Fernhoff, K.; Pistone, T.; Pasquini, L.; Wise, A. B.; Staffaroni, A. M.; Mandelli, M. L.; Lee, S. E.; Boxer, A. L.; Rankin, K. P.; Rabinovici, G. D.; Gorno-Tempini, M. L.; Rosen, H. J.; Kramer, J. H.; Miller, B. L.; Seeley, W. W.
10.1101/2023.12.01.569654 — neuroscience — Posted on 2023-12-06
3663 A biologically plausible decision-making model based on interacting cortical columns
Baspinar, E.; Cecchini, G.; DePass, M.; Andujar, M.; Pani, P.; Ferraina, S.; Moreno-Bote, R.; Cos, I.; Destexhe, A.
10.1101/2023.02.28.530384 — neuroscience — Posted on 2023-12-06
3664 Social cognitive regions of human association cortex are selectively connected to the amygdala
Edmonds, D.; Salvo, J. J.; Anderson, N.; Lakshman, M.; Yang, Q.; Kay, K.; Zelano, C.; Braga, R. M.
10.1101/2023.12.06.570477 — neuroscience — Posted on 2023-12-06
3667 A machine learning approach for quantifying age-related histological changes in the mouse kidney.
Sheehan, S.; Mawe, S.; Chen, M.; Klug, J.; Ladiges, W. C.; Korstanje, R.; Mahoney, J. M.
10.1101/2023.07.07.548002 — pathology — Posted on 2023-12-06
3673 Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice
Findley, C. A.; McFadden, S. A.; Hill, T.; Peck, M. R.; Quinn, K.; Hascup, K. N.; Hascup, E. R.
10.1101/2023.12.05.570100 — neuroscience — Posted on 2023-12-06
3676 Hippocampome.org v2.0: a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits
Wheeler, D. W.; Kopsick, J. D.; Sutton, N.; Tecuatl, C.; Komendantov, A. O.; Nadella, K.; Ascoli, G. A.
10.1101/2023.05.12.540597 — neuroscience — Posted on 2023-12-06
3678 Genetic requirements for uropathogenic E. coli proliferation in the bladder cell infection cycle
Mediati, D. G.; Blair, T. A.; Costas, A.; Monahan, L. G.; Söderström, B.; Charles, I. G.; Duggin, I. G.
10.1101/2023.12.05.570251 — microbiology — Posted on 2023-12-06
3679 Validation of cell-free protein synthesis aboard the International Space Station
Kocalar, S.; Miller, B. M.; Huang, A.; Gleason, E.; Martin, K.; Foley, K.; Copeland, D. S.; Jewett, M.; Saavedra, E. A.; Kraves, S.
10.1101/2023.12.06.570403 — synthetic biology — Posted on 2023-12-06
3680 Leaf- and diverged shoot meristem programs shape the stem in rice
Tsuda, K.; Maeno, A.; Otake, A.; Kato, K.; Tanaka, W.; Hibara, K.-I.; Nonomura, K.-I.
10.1101/2023.12.05.569800 — plant biology — Posted on 2023-12-06
3683 Spatial and temporal detection of root exudates with a paper-based microfluidic device
Patko, D.; Gunatilake, U. B.; Dupuy, L. X.; Basabe-Desmonts, L.; Benito-Lopez, F.
10.1101/2023.12.06.570394 — plant biology — Posted on 2023-12-06
3684 The cadmium-hypertolerant fern, Athyrium yokoscense, exhibits two cadmium stress mitigation strategies in the roots and the aerial parts
Ukai, Y.; Taoka, H.; Kamada, M.; Wakui, Y.; Goto, F.; Kitazaki, K.; Abe, T.; Hokura, A.; Yoshihara, T.; Shimada, H.
10.1101/2023.12.06.570362 — plant biology — Posted on 2023-12-06
3687 Root hydraulic properties: an exploration of their variability across scales
Cabrera, J. C. B.; Vanderborght, J.; Couvreur, V.; Behrend, D.; Gaiser, T.; Nguyen, T. H.; Lobet, G.
10.1101/2023.12.06.570353 — plant biology — Posted on 2023-12-06
3688 Deciphering lipid mutant phenotypes with a new genome-scale metabolic model of Microchloropsis gaditana encompassing detailed lipid metabolism
Dupont-Thibert, C.; Carneiro, S.; Pereira, B.; Careira, R.; Vilaca, P.; Finazzi, G.; Collin, S.; Marechal, E.; Billey, E.; Curien, G.; Durot, M.; Jouhet, J.
10.1101/2023.12.06.570374 — plant biology — Posted on 2023-12-06
3691 ERG1a K+ Channel Increases Intracellular Calcium Concentration through Modulation of Calsequestrin 1 in C2C12 Myotubes
Hockerman, G. H.; Pratt, E.; Guha, S.; LaVigne, E.; Whitmore, C.; Khader, O.; McClure, N.; Zampieri, S.; Koran, J.; Wang, W.-H.; Pond, A. L.
10.1101/2023.12.04.569937 — physiology — Posted on 2023-12-06
3693 Epithelial N-methyl-D-aspartate (NMDA) receptors mediate renal vasodilation by affecting kidney autoregulation.
Romero, C. A.; Lim, H.; Wang, H.; Wynne, B. M.; Ma, P.; Jing, Y.; Liotta, D.; D'Erasmo, M.; Traynelis, S.; Eaton, D.; Wall, S. M.
10.1101/2023.12.04.569973 — physiology — Posted on 2023-12-06
3694 Development of adaptive anoikis resistance promotes metastasis that can be overcome by CDK8/19 Mediator kinase inhibition
Monavarian, M.; Page, E. F.; Rajkarnikar, R.; Kumari, A.; Macias, L. Q.; Massicano, F.; Lee, N. Y.; Sahoo, S.; Hempel, N.; Jolly, M. K.; Ianov, L.; Worthey, E.; Singh, A.; Broude, E. V.; Mythreye, K.
10.1101/2023.12.04.569970 — cancer biology — Posted on 2023-12-06
3695 Species-level classification provides new insights into the biogeographical patterns of microbial communities in shallow saline lakes
Len, P.; Meirkhanova, A.; Nugumanova, G.; Cestaro, A.; Jeppesen, E.; Vorobjev, I. A.; Donati, C.; Barteneva, N. S.
10.1101/2023.12.06.570325 — ecology — Posted on 2023-12-06
3696 Nucleic acid sequence contributes to remodeler-mediated targeting of histone H2A.Z
Converso, C.; Pierrakeas, L.; Chan, L.; Chowdhury, S.; Kuznetsov, V. I.; Denu, J. M.; Luk, E.
10.1101/2023.12.06.570360 — molecular biology — Posted on 2023-12-06
3701 Queuosine Salvage in Bartonella henselae Houston 1: A Unique Evolutionary Path
Quaiyum, S.; Yuan, Y.; Sun, G.; Ratnayake, M.; Hutinet, G.; Dedon, P. C.; Minnick, M. F.; de Crecy-Lagard, V.
10.1101/2023.12.05.570228 — microbiology — Posted on 2023-12-06
3706 Translation in Bacillus subtilis is spatially and temporally coordinated during sporulation
Iwanska, O.; Latoch, P.; Kopik, N.; Kovalenko, M.; Lichocka, M.; Serwa, R.; Starosta, A. L.
10.1101/2023.12.06.569898 — microbiology — Posted on 2023-12-06
3707 Multimodal mucosal and systemic immune characterization of a novel non-human primate trachoma model highlights the critical role of local immunity during acute phase disease
Paulet, E.; Contreras, V.; Galhaut, M.; Rosenkrands, I.; Holland, M.; Burton, M.; Dietrich, J.; Gallouët, A.-S.; Bosquet, N.; Relouzat, F.; Langlois, S.; Follmann, F.; Le Grand, R.; Labetoulle, M.; Rousseau, A.
10.1101/2023.12.05.570239 — microbiology — Posted on 2023-12-06
3708 Role of Dusp5 KO on Vascular Properties of Middle Cerebral Artery in Rats
Tang, C.; Zhang, H.; Border, J. J.; Liu, Y.; Fang, X.; Jefferson, J. R.; Gregory, A.; Johnson, C.; Lee, T. J.; Bai, S.; Sharma, A.; Shin, S. M.; Yu, H.; Roman, R. J.; Fan, F.
10.1101/2023.12.04.569939 — physiology — Posted on 2023-12-06
3709 Three-dimensional assessments are necessary to determine the true spatial tissue composition of diseased tissues
Forjaz, A.; Vaz, E.; Romero, V. M.; Joshi, S.; Braxton, A. M.; Jiang, A. C.; Fujikura, K.; Cornish, T.; Hong, S.-M.; Hruban, R. H.; Wu, P.-H.; Wood, L. D.; Kiemen, A. L.; Wirtz, D.
10.1101/2023.12.04.569986 — cancer biology — Posted on 2023-12-06
3713 Structure and dynamics of the RF-amide QRFP receptor GPR103
Iwama, A.; Akasaka, H.; Sano, F. K.; Oshima, H. S.; Shihoya, W.; Nureki, O.
10.1101/2023.12.06.570340 — biochemistry — Posted on 2023-12-06
3715 A regional One Health approach to the risk of invasion by Anopheles stephensi in Mauritius
Iyaloo, D. P.; Zohdy, S.; Carney, R.; Mosawa, V. R.; Elahee, K. B.; Carter, T.; Bhoobun, H.; Spear, J.; Munglee, N.; Latchooman, N.; Puryag, S.; Bheecarry, A.; Bedja, S. A.
10.1101/2023.12.05.570234 — ecology — Posted on 2023-12-06
3718 Activation of Protein Kinase R (PKR) Plays a Pro-Viral Role in Mammarenavirus Infected Cells
Witwit, H.; Khafaji, R.; Salaniwal, A.; Kim, A.; Cubitt, B.; Ye, C.; Jackson, N.; Weiss, S. R.; Martinez-Sobrido, L.; de la Torre, J. C.
10.1101/2023.12.05.570143 — microbiology — Posted on 2023-12-06
3720 Unraveling the role of γδ T cells in the pathogenesis of an oncogenic avian herpesvirus
Sabsabi, M. A.; Kheimar, A.; You, Y.; von La Roche, D.; Härtle, S.; Göbel, T. W.; von Heyl, T.; Schusser, B.; Kaufer, B. B.
10.1101/2023.12.05.570256 — microbiology — Posted on 2023-12-06
3721 Bacterial pathogens dynamic during multi-species infections
Barny, M.-A.; Thieffry, S.; Gomez de Faria, C.; Thebault, E.; Pedron, J.
10.1101/2023.12.06.570389 — microbiology — Posted on 2023-12-06
3722 Single cell transcriptional changes across the blood stages of artemisinin resistant K13C580Y mutant Plasmodium falciparum upon dihydroartemisinin exposure
Oduor, C. I.; Cunningham, C.; Rustamzade, N.; Zuromski, J.; Chin, D. M.; Nixon, C. P.; Kurtis, J. D.; Juliano, J. J.; Bailey, J. A.
10.1101/2023.12.06.570387 — microbiology — Posted on 2023-12-06
3723 A therapeutic small molecule lead enhances γ-oscillations and improves cognition/memory in Alzheimer's disease model mice
Wei, X.; Campagna, J. J.; Jagodzinska, B.; Wi, D.; Cohn, W.; Lee, J. T.; Zhu, C.; Huang, C. S.; Molnar, L.; Houser, C. R.; John, V.; Mody, I.
10.1101/2023.12.04.569994 — neuroscience — Posted on 2023-12-06
3724 Auditory Aversive Generalization Learning Prompts Threat-Specific Changes in Alpha-Band Activity
Farkas, A. H.; Ward, R. T.; Gilbert, F. E.; Pouliot, J.; Chiasson, P.; McIlvanie, S.; Traiser, C.; Riels, K.; Mears, R.; Keil, A.
10.1101/2023.12.04.569971 — physiology — Posted on 2023-12-06
3727 Diversity of Insecticidal PA1b Homologs among Legume Seeds from Middle Eastern Region
Diya, F.; Charles, H.; Vallier, A.; Karaki, L.; Kfoury, L.; DA SILVA, P.; Rizk, F.
10.1101/2023.12.04.569987 — bioinformatics — Posted on 2023-12-06
3729 HIFU Thermal Ablation in Breast Cancer Cells: Monolayers vs. Spheroids
Badawe, H.; Harouz, J. P.; Raad, P.; Abu, K.; Kheir, W. A.; Ghali, K. A.; Khraiche, M.
10.1101/2023.12.04.569950 — bioengineering — Posted on 2023-12-06
3730 Elevation-dependent patterns of snow-gum dieback are moderated by trait differences between montane and subalpine forests.
Bryant, C.; Ball, M. C.; Borevitz, J. O.; Brookhouse, M. T.; Carle, H.; Cunningham, P.; Davey, M.; Davies, J.; Eason, A.; Erskine, J. D.; Fuenzalida, T. I.; Grishin, D.; Harris, R.; Kriticos, J.; Midson, A.; Nicotra, A. B.; Nshuti, A.; Ward-Jones, J.; Yao, Y.; Young, O.; Bothwell, H.
10.1101/2023.12.04.569996 — ecology — Posted on 2023-12-06
3733 Decreased voluntary alcohol intake and ventral striatal epigenetic and transcriptional remodeling in male Acss2 KO mice
Egervari, G.; Donahue, G.; Quijano-Carde, N.; Hogan, C.; Periandri, E. M.; Fleites, V.; Alexander, D. C.; De Biasi, M.; Berger, S. L.
10.1101/2023.12.04.569964 — neuroscience — Posted on 2023-12-06
3734 Neural Trajectories of Social Relationships on a Map-like Manifold
Schafer, M.; Kamilar-Britt, P.; Sahani, V.; Bachi, K.; Schiller, D.
10.1101/2023.12.04.569670 — neuroscience — Posted on 2023-12-06
3735 behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments
Bowler, J. C.; Zakka, G.; Yong, H. C.; Li, W.; Rao, B.; Liao, Z.; Priestley, J. B.; Losonczy, A.
10.1101/2023.12.04.569989 — neuroscience — Posted on 2023-12-06
3740 Nanoscale photobiotinylation, pulldown and sequencing of region-specific DNA from intact cells.
Zipfel, W.; Roberts, T.; Kushner, M.; Crowley, J. C.; Ozer, A.; Wang, J.; Ray, J.; Lis, J. T.
10.1101/2023.12.04.569951 — genomics — Posted on 2023-12-06
3742 Astrocyte-dependent local neurite pruning and Hox gene-mediated cell death in Beat-Va neurons
Lehmann, K. S.; Hupp, M. T.; Jefferson, A.; Cheng, Y.-C.; Sheehan, A. E.; Kang, Y.; Freeman, M.
10.1101/2023.12.05.570324 — neuroscience — Posted on 2023-12-06
3743 Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain
Peach, C. J.; Tonello, R.; Gomez, K.; Calderon-Rivera, A.; Rodriguez Sanchez, M.; Maile, L.; Perez-Miller, S.; Manu, A.-M.; Hahn, H.; Thomsen, A. R. B.; Schmidt, B. L.; Davidson, S.; Khanna, M.; Khanna, R.; Bunnett, N. W.
10.1101/2023.12.06.570398 — neuroscience — Posted on 2023-12-06
3744 The impact of gravity on functional movements: kinematic insights and features selection
Bucchieri, A.; Tessari, F.; Buccelli, S.; De Momi, E.; Laffranchi, M.; De Michieli, L.
10.1101/2023.12.05.570204 — neuroscience — Posted on 2023-12-06
3748 Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons
Scheiffele, P.; Di Bartolomei, G.; Ortiz, R.; Schreiner, D.; Falkner, S.; Creemers, E. E.
10.1101/2023.12.06.570345 — neuroscience — Posted on 2023-12-06
3749 Rapid, concerted switching of the neural code in inferotemporal cortex
Shi, Y.; Bi, D.; Hesse, J. K.; Lanfranchi, F. F.; Chen, S.; Tsao, D. Y.
10.1101/2023.12.06.570341 — neuroscience — Posted on 2023-12-06
3750 A Kaspar Hauser experiment for innateness of numerical cognition
Lorenzi, E.; Perrino, M.; Zanon, M.; Messina, A.; Vallortigara, G.
10.1101/2023.12.06.570352 — neuroscience — Posted on 2023-12-06
3751 Unravelling effects of fine-scale changes within wild-bird flocks on sociality
Troisi, C. A.; Firth, J. A.; Crofts, S. J.; Davidson, G. L.; Reichert, M. S.; Quinn, J. L.
10.1101/2023.12.05.569701 — animal behavior and cognition — Posted on 2023-12-06
3753 Multitask Learning of Biophysically-Detailed Neuron Models
Verhellen, J.; Beshkov, K.; Amundsen, S.; Ness, T. V.; Einevoll, G. T.
10.1101/2023.12.05.570220 — neuroscience — Posted on 2023-12-06
3758 Brainstem arousal systems adaptively shape large-scale cortical interactions for flexible decision-making
van den Brink, R. L.; Hagena, K.; Wilming, N.; Murphy, P. R.; Calder-Travis, J.; Finsterbusch, J.; Büchel, C.; Donner, T. H.
10.1101/2023.12.05.570327 — neuroscience — Posted on 2023-12-06
3759 Beta and theta oscillations track effort and previous reward in human basal ganglia and prefrontal cortex during decision making
Hoy, C. W.; de Hemptinne, C.; Wang, S. S.; Harmer, C. J.; Apps, M. A. J.; Husain, M.; Starr, P. A.; Little, S.
10.1101/2023.12.05.570285 — neuroscience — Posted on 2023-12-06
3763 Characterization of DNA methylation reader proteins of Arabidopsis thaliana
Cahn, J.; Lloyd, J. P. B.; Karemaker, I. D.; Jansen, P. W.; Pflueger, J.; Duncan, O.; Petereit, J.; Bogdanovic, O.; Millar, H.; Vermeulen, M.; Lister, R.
10.1101/2023.12.05.570080 — plant biology — Posted on 2023-12-06
3764 A non-conducting role of the Cav1.4 Ca2+ channel drives homeostatic plasticity at the cone photoreceptor synapse
Maddox, W.; Ordemann, G. J.; de la Rosa Vazquez, J.; Huang, A.; Gault, C.; Wisner, S. R.; Randall, K.; Futagi, D.; DeVries, S.; Hoon, M.; Lee, A.
10.1101/2023.12.05.570129 — neuroscience — Posted on 2023-12-06
3766 Hybrid Neural Networks of the Olfactory Learning Center in the Drosophila Brain
Cheng, L.-S.; Charng, C.-C.; Chen, R.-H.; Feng, K.-L.; Chiang, A.-S.; Lo, C.-C.; Lee, T.-K.
10.1101/2023.12.06.570338 — neuroscience — Posted on 2023-12-06
3767 Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma
Machour, F. E.; Abu-Zhayia, E.; Kamar, J.; Barisaac, A. S.; Simon, I.; Ayoub, N.
10.1101/2023.02.19.529108 — molecular biology — Posted on 2023-12-06
3768 Integrative omics analysis reveals gene regulatory mechanisms distinguishing organoid-derived hepatocytes from primary human hepatocytes
Wu, H.; Yang, A. S.-P.; Stelloo, S.; Roos, F. J. M.; te Morsche, R. H. M.; Verkerk, A. H.; Luna-Velez, M. V.; Wingens, L.; de Wilt, J. H. W.; Sauerwein, R. W.; Mulder, K.; van Heeringen, S. J.; Verstegen, M.; J.W. van der Laan, L.; Marks, H.; Bartfai, R.
10.1101/2023.12.05.570132 — molecular biology — Posted on 2023-12-06
3769 Identification of a P62-TIF-IA axis that drives nucleolar fusion and the senescence associated secretory phenotype
Thoms, H. C.; Brant, T.; Duckett, K.; Yang, Y.; Dong, J.; Wang, H.; Derby, F.; Akeke, T.; Mann, D.; Millar, F. R.; Von Kriegsheim, A.; Acosta, J. C.; Oakley, F.; Stark, L. A.
10.1101/2023.12.05.570133 — molecular biology — Posted on 2023-12-06
3772 Liebig's law of the minimum in the TGF-β/SMAD pathway
Li, Y.; Deng, D.; Höfer, C. T.; Kim, J.; Heo, W. D.; Xu, Q.; Liu, X.; Zi, Z.
10.1101/2023.07.10.548398 — systems biology — Posted on 2023-12-06
3773 Mechanistic basis of the dynamic response of TWIK1 ionic selectivity to pH
Chatelain, F. C.; Gilbert, N.; Bichet, D.; Jauch, A.; Feliciangeli, S.; LESAGE, F.; Bignucolo, O.
10.1101/2023.11.09.566352 — biochemistry — Posted on 2023-12-06
3774 Modulation of human kinase activity through direct interaction with SARS-CoV-2 proteins
Halwachs, B.; Moesslacher, C. S.; Kohlmayr, J. M.; Fasching, S.; Masser, S.; Choteau, S. A.; Zanzoni, A.; Kunowska, N.; Stelzl, U.
10.1101/2023.11.27.568816 — biochemistry — Posted on 2023-12-06
3778 Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8
PEREZ, Y.; ALHOURANI, F.; PATOUILLARD, J.; Ribeyre, C.; Larroque, M.; BALDIN, V.; Lleres, D.; GRIMAUD, C.; JULIEN, E.
10.1101/2023.11.22.567520 — molecular biology — Posted on 2023-12-06
3779 Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86 lineages combining increased fitness and antibody evasion
Planas, D.; Staropoli, I.; Michel, V.; Lemoine, F.; Donati, F.; Prot, M.; Porrot, F.; Benhassine, F. G.; Jeyarajah, B.; Brisebarre, A.; Dehan, O.; Avon, L.; Bolland, W.; Hubert, M.; Buchreiser, J.; Vanhoucke, T.; Rosenbaum, P.; Veyer, D.; Pere, H.; Lina, B.; Assant, S. T.; Hocqueloux, L.; Prazuck, T.; Loriere, E. S.; Schwartz, O.
10.1101/2023.11.20.567873 — microbiology — Posted on 2023-12-06
3782 LINE-1 retrotransposon activation intrinsic to interneuron development
Bodea, G. O.; Botto, J. M.; Ferreiro, M. E.; Sanchez-Luque, F. J.; de los Rios Barreda, J.; Rasmussen, J.; Rahman, M. A.; Fenlon, L. R.; Jansz, N.; Gubert, C.; Gerdes, P.; Bodea, L.-G.; Ajjikuttira, P.; Da Costa Guevara, D. J.; Cumner, L.; Bell, C. C.; Kozulin, P.; Billon, V.; Morell, S.; Kempen, M.-J. H.; Love, C. J.; Saha, K.; Palmer, L. M.; Ewing, A. D.; Jhaveri, D. J.; Richardson, S. R.; Hannan, A. J.; Faulkner, G. J.
10.1101/2022.03.20.485017 — genomics — Posted on 2023-12-06
3783 Pre-mRNA fate decision safeguards the fidelity of the inflammatory response
Bestehorn, A. M.; Fesselet, J. A. M.; Didusch, S.; Zeiler, C.; Doppelmayer, K.; Borroni, M.; Le Heron, A.; Pfanzagl, V.; Chen, W.; Scinicariello, S.; Baccarini, M.; Versteeg, G. A.; Hartl, M.; Kovarik, P.
10.1101/2023.11.30.569392 — molecular biology — Posted on 2023-12-06
3786 High-throughput ML-guided design of diverse single-domain antibodies against SARS-CoV-2
Angermueller, C.; Marie, Z.; Jester, B.; Engelhart, E.; Emerson, R.; Alipanahi, B.; Lin, C.; Shikany, C.; Guion, D.; Nelson, J.; Kelley, M.; McMurray, M.; Shaffer, P.; Cordray, C.; Halabiya, S.; McCaw, Z. R.; Struyvenberg, S.; Aggarwal, K.; Ertel, S.; Martinez, A.; Ozarkar, S.; Hager, K.; Frumkin, M.; Roberts, J.; Lopez, R. M.; Younger, D.; Colwell, L.
10.1101/2023.12.01.569227 — bioinformatics — Posted on 2023-12-06
3792 Genetic heterogeneity in the Salmonella Typhi Vi capsule locus: A population genomic study from Fiji
Getahun Strobel, A.; Hayes, A. J.; Wirth, W.; Mua, M.; Saumalua, T.; Cabenatabua, O.; Soqo, V.; Rosa, V.; Wang, N.; Lacey, J. A.; Hocking, D.; Valcanis, M.; Jenney, A.; Howden, B. P.; Duchene, S.; Mullholland, K.; Strugnell, R. A.; Davies, M. R.
10.1101/2023.12.04.569801 — microbiology — Posted on 2023-12-06
3793 XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against emerging SARS-CoV-2 variants
Wang, Q.; Guo, Y.; Bowen, A.; Mellis, I. A.; Valdez, R.; Gherasim, C.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2023.11.26.568730 — immunology — Posted on 2023-12-06
3800 Dorsal hippocampal oxytocin receptor regulates adult peer bonding in rats
Hu, Y.; Li, W.; Zhao, Y.; Liu, Y.; Sun, W.; Yan, Y.; Liu, L.; Deng, B.; Fan, P.
10.1101/2023.12.04.570022 — neuroscience — Posted on 2023-12-05
3802 Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion
Polsani, N.; Yung, T.; Thomas, E. C.; Phung-Rojas, M.; Gupta, I.; Denker, J.; Feng, X.; Ibarra, B.; Hopyan, S.; Atit, R.
10.1101/2023.12.05.570300 — developmental biology — Posted on 2023-12-05
3803 Distinct secretomes in p16- and p21- positive senescent cells across tissues
Saul, D.; Jurk, D.; Doolittle, M. L.; Kosinsky, R. L.; Monroe, D.; LeBrasseur, N.; Robbins, P. D.; Niedernhofer, L.; Khosla, M.D, S.; Passos, J.
10.1101/2023.12.05.569858 — cell biology — Posted on 2023-12-05
3806 Maternal SMARCA5 is required for major ZGA in mouse embryos
Kubinyecz, O. N.; Drage, D.; Santos Constancia, M. d. F.; Krueger, C.; Okkenhaug, H.; Taubenschmid-Stowers, J.; Reik, W.
10.1101/2023.12.05.570276 — developmental biology — Posted on 2023-12-05
3808 ERK3 Is Involved in Regulating Cardiac Fibroblast Function
Sahadevan, P.; Dingar, D.; Nawaito, S. A.; Nair, R. S.; Trepanier, J.; Sahmi, F.; Shi, Y.; Gillis, M.-A.; Sirois, M. G.; Meloche, S.; Tardif, J.-C.; Allen, B. G.
10.1101/2023.12.05.570171 — cell biology — Posted on 2023-12-05
3809 Packaging of supplemented urokinase into naked alpha-granules of in vitro-grown megakaryocytes for targeted therapeutic delivery
Poncz, M.; Zaitsev, S. V.; Ahn, H.; Kowalska, M. A.; Bdeir, K.; Camire, R. M.; Cines, D. B.; Stepanova, V.
10.1101/2023.12.05.570278 — cell biology — Posted on 2023-12-05
3812 An evolution-based framework for describing human gut bacteria
Doran, B. A.; Chen, R. Y.; Giba, H.; Behera, V.; Barat, B.; Sundararajan, A.; Lin, H.; Sidebottom, A.; Pamer, E. G.; Raman, A.
10.1101/2023.12.04.569969 — systems biology — Posted on 2023-12-05
3814 Transcription attenuation in synthetic promoters in tandem formation
Chauhan, V.; Baptista, I. S. C.; Jagadeesan, R.; Dash, S.; Ribeiro, A. S.
10.1101/2023.12.05.569149 — synthetic biology — Posted on 2023-12-05
3816 IGF2BP1 phosphorylation regulates ribonucleoprotein condensate formation by impairing low-affinity protein and RNA interactions
Hornegger, H.; Muratovic, A.; Anisimova, A. S.; Burgeois, B. R.; Spinetti, E.; Covino, R.; Madl, T.; Karagoz, G. E.
10.1101/2023.12.05.570121 — biochemistry — Posted on 2023-12-05
3817 Four-Core Genotypes mice harbour a 3.2MB X-Y translocation that perturbs Tlr7 dosage
Panten, J.; Del Prete, S.; Cleland, J. P.; Saunders, L. M.; van Riet, J.; Schneider, A.; Ginno, P. A.; Schneider, N.; Koch, M.-L.; Gerstung, M.; Stegle, O.; Turner, J. M. A.; Heard, E.; Odom, D. T.
10.1101/2023.12.04.569933 — genetics — Posted on 2023-12-05
3818 The Effect of Pseudoknot Base Pairing on Cotranscriptional Structural Switching of the Fluoride Riboswitch
Hertz, L. M.; White, E. N.; Kuznedelov, K.; Cheng, L.; Yu, A. M.; Kakkaramadam, R.; Severinov, K.; Chen, A.; Lucks, J. B.
10.1101/2023.12.05.570056 — molecular biology — Posted on 2023-12-05
3819 Investigating the potential of X shredding for mouse genetic biocontrol
Bunting, M. D.; Godahewa, G. I.; McPherson, N. O.; Robertson, L.; Gierus, L.; Piltz, S. G.; Edwards, O.; Tizard, M.; Thomas, P. Q.
10.1101/2023.12.05.570030 — molecular biology — Posted on 2023-12-05
3825 Development of a new 3D tracking system for multiple marmosets under free-moving conditions
Yurimoto, T.; Kumita, W.; Sato, K.; Kikuchi, R.; Shibuki, Y.; Hashimoto, R.; Kamioka, M.; Hayasegawa, Y.; Yamazaki, E.; Kurotaki, Y.; Goda, N.; Kitakami, J.; Fujita, T.; Inoue, T.; Sasaki, E.
10.1101/2022.03.29.486138 — animal behavior and cognition — Posted on 2023-12-05
3826 Dissection of a non-coding risk locus at 1p36.23 identifies ERRFI1 as a novel gene in the pathogenesis of psoriasis and psoriatic arthritis
Gough, O. J.; Rane, S. S.; Saunders, A.; Priestley, M.; Ray-Jones, H.; Shi, C.; Warren, R. B.; Adamson, A.; Eyre, S.
10.1101/2023.12.04.569945 — genomics — Posted on 2023-12-05
3827 Cell type-specific loops linked to RNA polymerase II elongation in human neural differentiation
Titus, K. R.; Simandi, Z.; Chandrashekar, H.; Paquet, D.; Phillips-Cremins, J. E.
10.1101/2023.12.04.569731 — genomics — Posted on 2023-12-05
3829 Rapid turnover of pathogen-blocking Wolbachia and their incompatibility loci
Shropshire, D.; Conner, W. R.; Vanderpool, D.; Hoffmann, A. A.; Turelli, M.; Cooper, B. S.
10.1101/2023.12.04.569981 — evolutionary biology — Posted on 2023-12-05
3832 The molecular and cellular anatomy of a fetal programming defect: the impact of low protein diet on the developing kidney.
Short, K. M.; Tortelote, G. G.; Jones, L. K.; Diniz, F.; Edgington-Giordano, F.; Cullen-McEwen, L. A.; Schröder, J.; Spencer, A.; Keniry, A.; Polo, J. M.; Bertram, J. F.; Blewitt, M. E.; Smyth, I. M.; El-dahr, S. S.
10.1101/2023.12.04.569988 — developmental biology — Posted on 2023-12-05
3834 Dimerization of ADAR1 modulates site-specificity of RNA editing
Mboukou, A.; Rajendra, V.; Messmer, S.; Catala, M.; Tisne, C.; Jantsch, M. F.; Barraud, P.
10.1101/2023.12.05.570066 — molecular biology — Posted on 2023-12-05
3838 Structural basis of tRNA recognition by the m3C-RNA-methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase
Throll, P.; Dolce, L. G.; Lastres, P. R.; Arnold, K.; Tengo, L.; Basu, S.; Kaiser, S.; Schneider, R.; Kowalinski, E.
10.1101/2023.12.05.570192 — molecular biology — Posted on 2023-12-05
3841 Control of asparagine homeostasis in Bacillus subtilis: Identification of promiscuous amino acid importers and exporters
Meissner, J.; Konigshof, M.; Wrede, K.; Warneke, R.; Mardoukhi, M. S. Y.; Commichau, F. M.; Stuelke, J.
10.1101/2023.12.05.570048 — microbiology — Posted on 2023-12-05
3842 Perception of butenolides by Bacillus subtilis via the α/β-hydrolase RsbQ
Melville, K. T.; Kamran, M.; Yao, J.; Costa, M.; Holland, M.; Taylor, N. L.; Fritz, G.; Waters, M. T.
10.1101/2023.12.05.570042 — microbiology — Posted on 2023-12-05
3843 The hydrogen isotope signatures of autotrophy versus heterotrophy recorded in archaeal tetraether lipids
Rhim, J. H.; Kopf, S.; McFarlin, J.; Batther, H.; Harris, C. M.; Zhou, A.; Feng, X.; Weber, Y.; Hoeft-McCann, S.; Pearson, A.; Leavitt, W. D.
10.1101/2023.11.29.569324 — microbiology — Posted on 2023-12-05
3851 Three-dimensional virtual H&E staining of label-free colon cancer tissue using holotomography and deep learning
park, J.; Shin, S.-J.; kim, g.; cho, H.; ryu, d.; ahn, d.; heo, j. e.; min, h.-s.; Lee, K. S.; Park, Y.
10.1101/2023.12.04.569853 — cancer biology — Posted on 2023-12-05
3853 Improving generalizability for MHC-binding peptide predictions through structure-based geometric deep learning
Marzella, D. F.; Crocioni, G.; Radusinovic, T.; Lepikhov, D.; Severin, H.; Bodor, D. L.; Rademaker, D. T.; Lin, C.; Georgievska, S.; Kessler, A. L.; Lopez-Tarifa, P.; Buschow, S.; Bekkers, E.; Xue, L. C.
10.1101/2023.12.04.569776 — bioinformatics — Posted on 2023-12-05
3854 Stereopy: modeling comparative and spatiotemporal cellular heterogeneity via multi-sample spatial transcriptomics
Fang, S.; Xu, M.; Cao, L.; Liu, X.; Bezulj, M.; Tan, L.; Yuan, Z.; Li, Y.; Xia, T.; Guo, L.; Kovacevic, V.; Xu, J.; Guo, L.; Liu, C.; Cheng, M.; Lin, L.; Wen, Z.; Josic, B.; Milicevic, N.; Qiu, P.; Lu, Q.; Li, Y.; Wang, L.; Hu, L.; Zhang, C.; Kang, Q.; Chen, F.; Deng, Z.; Li, J.; Li, M.; Li, S.; Zhao, Y.; Fan, G.; Zhang, Y.; Chen, A.; Li, Y.; Xu, X.
10.1101/2023.12.04.569485 — bioinformatics — Posted on 2023-12-05
3855 Image-based force inference by biomechanical simulation
Vanslambrouck, M.; Thiels, W.; Vangheel, J.; Smeets, B.; Jelier, R.
10.1101/2023.12.01.569682 — bioinformatics — Posted on 2023-12-05
3860 Transcriptomic responses of sponge holobionts to in situ, seasonal anoxia and hypoxia
Strehlow, B. W.; Schuster, A.; Francis, W. R.; Eckford-Soper, L.; Kraft, B.; McAllen, R.; Nielsen, R.; Mandrup, S.; Canfield, D. E.
10.1101/2023.02.27.530229 — ecology — Posted on 2023-12-05
3862 Tardigrade secretory proteins protect biological structures from desiccation
Lim, S.; Reilly, C. B.; Barghouti, Z.; Marelli, B.; Way, J. C.; Silver, P. A.
10.1101/2023.12.04.570007 — molecular biology — Posted on 2023-12-05
3863 Genetic heterogeneity in the Salmonella Typhi Vi capsule locus: A population genomic study from Fiji
Davies, M. R.; Getahun Strobel, a.; Hayes, A. J.; Wirth, W.; Mua, M.; Saumalua, T.; Cabenatabua, O.; Soqo, V.; Rosa, V.; Wang, N.; Lacey, J. A.; Hocking, D.; Valcanis, M.; Jenney, A.; Howden, B. P.; Duchene, S.; Mullholland, K.; Strugnell, R. A.
10.1101/2023.12.04.569801 — microbiology — Posted on 2023-12-05
3865 Endolysin B: A new archetype in M. tuberculosis treatment
Griego, A.; Antinori, B.; Spitaleri, A.; Muzzolini, I.; Muzzioli, S.; Calo, L.; Moschetti, G.; Genta, M.; Scarpa, E.; De Matteis, V.; Miggiano, R.; Ricagno, S.; Rizzello, L.
10.1101/2023.12.05.569960 — microbiology — Posted on 2023-12-05
3866 Control of the phage defence mechanisms by Quorum sensing (QS) in clinical isolates of Klebsiella pneumoniae
Barrio-Pujante, A.; Bleriot, I.; Blasco, L.; Fernandez-Garcia, L.; Pacios, O.; Ortiz-Cartagena, C.; Lopez, M.; Fernandez-Cuenca, F.; Oteo-Iglesias, J.; Tomas, M.
10.1101/2023.12.05.570179 — microbiology — Posted on 2023-12-05
3867 Fibroblast activation protein regulates natural killer cell migration, extravasation and tumor infiltration
Fitzgerald, A. A.; Maynard, R. E.; Marcisak, E. F.; Nasir, A.; Glasgow, E.; Jablonski, S.; Van der Veken, P.; Pearson, G.; Eisman, S. E.; Mace, E. M.; Fertig, E. J.; Weiner, L. M.
10.1101/2021.02.03.429622 — immunology — Posted on 2023-12-05
3879 Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis
Bernou, C.; Mouthon, M.-A.; Daynac, M.; Kortulewski, T.; Demaille, B.; Barroca, V.; Couillard-Despres, S.; Dechamps, N.; Menard, V.; Bellenger, L.; Antoniewski, C.; Chicheportiche, A.; Boussin, F. D.
10.1101/2023.03.12.532290 — genomics — Posted on 2023-12-05
3884 Integrated Molecular-Phenotypic Profiling Reveals Metabolic Control of Morphological Variation in Stembryos
Villaronga Luque, A.; Savill, R. G.; Lopez-Anguita, N.; Bolondi, A.; Garai, S.; Gassaloglu, S. I.; Poddar, A.; Bulut-Karslioglu, A.; Veenvliet, J. V.
10.1101/2023.12.04.569921 — developmental biology — Posted on 2023-12-05
3885 Metabolic control of germ layer proportions through regulation of Nodal and Wnt signalling
Stapornwongkul, K. S.; Hahn, E. M.; Palau, L. S.; Arato, K.; Gritti, N.; Anlas, K.; Polinski, P.; Lopez, M.; Ebisuya, M.; Trivedi, V.
10.1101/2023.12.04.569862 — developmental biology — Posted on 2023-12-05
3887 Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies
Parthasarathy, D.; Pothula, K. R.; Dam, K.-M. A.; Ratnapriya, S.; Benet, H. C.; Parsons, R.; Huang, X.; Sammour, S.; Janowska, K.; Harris, M.; Sacco, S.; Sodroski, J.; Bridges, M.; Hubbell, W.; Acharya, P.; Herschhorn, A.
10.1101/2023.09.13.557082 — microbiology — Posted on 2023-12-05
3890 A Drosophila model of mitochondrial disease phenotypic heterogeneity
Granat, L.; Knorr, D. Y.; Ranson, D. C.; Chakrabarty, R. P.; Chandel, N.; Bateman, J. M.
10.1101/2023.12.05.570102 — neuroscience — Posted on 2023-12-05
3896 Role of Immature Choroid Plexus in the Pathology of Autism Spectrum Disorder
Tanabe, M.; Saito, Y.; Takasaki, A.; Nakano, K.; Suzuki, C.; Kawamura, N.; Hattori, A.; Nagashima, S.; Oikawa, M.; Yanagi, S.; Yamaguchi, T.; Fukuda, T.
10.1101/2023.12.01.569662 — neuroscience — Posted on 2023-12-05
3898 New algorithm for pearl millet modelling in APSIM allowing a mechanistic simulation of tillers
Garin, V.; Van Oosterom, E.; McLean, G.; Hammer, G.; Murugesan, T.; Kaliamoorthy, S.; Diancumba, M.; Hajjarpoor, A.; Kholova, J.
10.1101/2023.02.12.528159 — plant biology — Posted on 2023-12-05
3901 Common types of microdebris affect the physiology of reef-building corals
Reichert, J.; Tirpitz, V.; Plaza, K.; Woerner, E.; Boesser, L.; Kuehn, S.; Primpke, S.; Schubert, P.; Ziegler, M.; Wilke, T.
10.1101/2023.12.04.569976 — physiology — Posted on 2023-12-05
3904 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signaling in the tumour microenvironment
Mukherjee, A. K.; Dutta, S.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Chatterjee, M.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; anand, V.; Perwez, A.; George, N.; Faruq, M.; Gupta, I.; Sabarinathan, R.; Chowdhury, S.
10.1101/2021.12.07.471419 — cancer biology — Posted on 2023-12-05
3905 Dysregulated Repeat Element Viral-like Immune Response in Hepatocellular Carcinoma
Coley, A. K.; Lu, C.; Pankaj, A.; Emmett, M. J.; Lang, E. R.; Song, Y.; Xu, K. H.; Xu, N.; Patel, B. K.; Chougule, A.; Nieman, L. T.; Aryee, M.; Ferrone, C. R.; Deshpande, V.; Franses, J. W.; Ting, D. T.
10.1101/2023.12.04.570014 — cancer biology — Posted on 2023-12-05
3906 STIL overexpression shortens lifespan and reduces tumor formation in mice
Moussa, A. T.; Cosenza, M. R.; Wohlfromm, T.; Brobeil, K.; Hill, A.; Patrizi, A.; Mueller-Decker, K.; Holland-Letz, T.; Jauch, A.; Kraft, B.; Kraemer, A.
10.1101/2023.12.04.569842 — cancer biology — Posted on 2023-12-05
3909 BayesAge: A Maximum Likelihood Algorithm To Predict Epigenetic Age
Mboning, L.; Rubbi, L.; Thompson, M.; Bouchard, L.-S.; Pellegrini, M.
10.1101/2023.12.03.569788 — bioinformatics — Posted on 2023-12-05
3910 Overcoming Observation Bias for Cancer Progression Modeling
Schill, R.; Klever, M.; Loesch, A.; Hu, Y. L.; Vocht, S.; Rupp, K.; Grasedyck, L.; Spang, R.; Beerenwinkel, N.
10.1101/2023.12.03.569824 — bioinformatics — Posted on 2023-12-05
3916 Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer
Meunier, A.; Hernandez-Castro, J. A.; Chahley, N.; Communal, L.; Kheireddine, S.; Koushki, N.; Davoudvandi, N.; Al Habyan, S.; Peant, B.; Lazaris, A.; Ng, A.; Veres, T.; McCaffrey, L.; Provencher, D.; Metrakos, P.; Mes-Masson, A.-M.; Juncker, D.
10.1101/773507 — bioengineering — Posted on 2023-12-05
3917 Silk Road Revealed: Mechanism of silk fibre formation in Bombyx mori
Moreno-Tortolero, R. O.; Luo, Y.; Parmeggiani, F.; Skaer, N.; Walker, R.; Serpell, L. O.; Holland, C.; Davis, S. A.
10.1101/2023.06.02.543394 — biochemistry — Posted on 2023-12-05
3919 An improved chromosome-level genome assembly of perennial ryegrass (Lolium perenne L.)
Chen, Y.; Koelliker, R.; Mascher, M.; Copetti, D.; Himmelbach, A.; Stein, N.; Studer, B.
10.1101/2023.12.05.570088 — genomics — Posted on 2023-12-05
3920 Signals of positive selection in Palearctic bat species coexisting with a fungal pathogen
Twort, V. G.; Laine, V. N.; Whiting-Fawcett, F.; Ito dos Santos, F.; Lilley, T.; Field, K.
10.1101/2023.12.04.569365 — evolutionary biology — Posted on 2023-12-05
3922 Extracellular symbiont colonizes insect during embryo development
Porras, M. A. G.; Pons, I.; Garcia-Lozano, M.; Jagdale, S.; Emmerich, C.; Weiss, B.; Salem, H.
10.1101/2023.12.04.569952 — evolutionary biology — Posted on 2023-12-05
3924 Strong cascading impacts of micropollutants on planktonic food web in urban river
Adyari, B.; Zhang, L.; Nascimento, F. J. d. A.; Zhang, Y.; Cao, M.; Wang, J.; Li, H.; Sun, Q.; Yu, C.; Hu, A.
10.1101/2023.12.03.569813 — ecology — Posted on 2023-12-05
3928 Intronic polyadenylation isoforms in the 5' part of genes constitute a source of microproteins and are involved in cell response to cisplatin
DEVAUX, A.; TANAKA, I.; CADIX, M.; HENEMAN-MASUREL, A.; Michallet, S.; FOUILLEUL, Q.; CHAKRABORTY, A.; LABBE, C. M.; FONTRODONA, N.; CLAUDE, J.-B.; DELOGER, M.; GESTRAUD, P.; TESSIER, L.; MORTADA, H.; LAMEIRAS, S.; RAYNAL, V.; BAULANDE, S.; Servant, N.; Auboeuf, D.; EYMIN, B.; Vagner, S.; DUTERTRE, M.
10.1101/2023.12.05.569446 — molecular biology — Posted on 2023-12-05
3929 High throughput screening identifies broad-spectrum Coronavirus entry inhibitors
Khan, S.; Partuk, E. O.; Chiaravalli, J.; Kozer, N.; Shurrush, K. A.; Elbaz-Alon, Y.; Scher, N.; Giraud, E.; Tran-Rajau, J.; Agou, F.; Barr, H. M.; Avinoam, O.
10.1101/2023.12.04.569985 — microbiology — Posted on 2023-12-05
3930 Influenza infected macrophages release viral ribonucleoproteins that shape the local host response
Fritzlar, S.; Lakdawala, S.; Roberts, J. A.; Coin, L. J. M.; Deng, Y.-M.; Moselen, J.; Le Sage, V.; Mackenzie, J.; Labzin, L.; Brooks, A. G.; Reading, P.; Londrigan, S.
10.1101/2023.12.04.570004 — microbiology — Posted on 2023-12-05
3933 Elevated mutation rates in the multi-azole resistant Aspergillus fumigatus cladedrives rapid evolution of antifungal resistance
Bottery, M. J.; van Rhijn, N. J.; Chown, H.; Rhodes, J. L.; Celia-Sanchez, B. N.; Brewer, M. T.; Momany, M.; Fisher, M. C.; Knight, C. G.; Bromley, M. J.
10.1101/2023.12.05.570068 — microbiology — Posted on 2023-12-05
3934 Excess fermentation and lactic acidosis as detrimental functions of the gut microbes in treatment-naive TB patients
Yunusbaeva, M.; Borodina, L.; Terentyeva, D.; Bogdanova, A.; Zakirova, A.; Bulatov, S.; Altinbaev, R.; Bilalov, F.; Yunusbayev, B.
10.1101/2023.12.05.570051 — microbiology — Posted on 2023-12-05
3935 PTPN1/2 inhibition induces highly functional terminal effector CD8 T cells through autocrine IL-10
Perez-Quintero, L. A.; Poirier, A.; Martinez-Cordoba, Z.; Feng, C.-H.; Aubry, I.; Carli, C.; Kamyabiazar, S.; Pacis, A.; Zolotarov, Y.; Pike, K.-A.; Delisle, J.-S.; Tremblay, M. L.
10.1101/2023.04.17.537264 — immunology — Posted on 2023-12-05
3936 Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming
Chung, H. K.; Liu, C.; Sun, M.; Casillas, E.; Chen, T.; Chick, B.; Wang, J.; Mcdonald, B.; Wang, J.; He, P.; Yang, Q.; Varanasi, S. K.; Mann, T.; Chen, D.; Hoffmann, F.; Tripple, V.; Hang, Y.; Ho, J.; Cho, U. H.; Williams, A.; Wang, Y.; Hargreaves, D.; Kaech, S. M.; Wang, W.
10.1101/2023.01.03.522354 — immunology — Posted on 2023-12-05
3940 Opportunities to improve goat production and food security in Botswana through forage nutrition and the use of supplemental feeds
Cooke, A. S.; Machekano, H.; Ventura-Cordero, J.; Louro-Lopez, A.; Joseph, V.; Gwiriri, L. C.; Takahashi, T.; Morgan, E. R.; Lee, M. R. F.; Nyamukondiwa, C.
10.1101/2023.12.04.569865 — zoology — Posted on 2023-12-05
3943 Planting diversity begets multifaceted tree diversity in oil palm landscapes
Paterno, G. B.; Brambach, F.; Guerrero-Ramirez, N.; Zemp, D. C.; Cantillo-Rodriguez, A. F.; Camarretta, N.; Moura, C. C. M.; Gailing, O.; Ballauff, J.; Polle, A.; Schlund, M.; Erasmi, S.; Iddris, N. A.-A.; Khokthong, W.; Sundawati, L.; Irawan, B.; Holscher, D.; Kreft, H.
10.1101/2023.12.04.566521 — ecology — Posted on 2023-12-05
3944 Targeting endothelial FOXO1 protects diabetic β-cells and improves wound healing
Wu, H.; Cui, K.; Zhu, B.; Lu, Y. W.; Sun, L.; Ma, Q.; Jian, A.; Hurtado, D. O.; Gao, X.; Li, Y.; Bhattacharjee, S.; Fu, H.; Birsner, A. E.; Malovichko, M.; Li, M.; Wang, B.; Singh, B.; Peng, Q.; Wong, S.; Norton, V.; Li, K. s.; Eisa-Beygi, S.; Wang, D.; Cowan, D. B.; Bielenberg, D. R.; Srivastava, S.; Rockowitz, S.; Xu, J.; D'Amato, R. J.; Chen, K.; Dong, M.; Biddinger, S.; Chen, H.
10.1101/2023.12.04.569948 — cell biology — Posted on 2023-12-05
3946 Multi-variate statistical and machine learning reveals the interplay between sex and age in antibody responses to de novo SARS-CoV-2 infection and vaccination
Cuperlovic-Culf, M.; Bennett, S.; Galipeau, Y.; McCluskie, P. S.; Arnold, C.; Bagheri, S.; Cooper, C. L.; Langlois, M.-A.; Fritz, J.; A. Piccirillo, C.; Crawley, A. M.
10.1101/2023.12.05.569965 — immunology — Posted on 2023-12-05
3948 The Effects of Preeclamptic Milieu on Cord Blood Derived Endothelial Colony-Forming Cells
Hall, E.; Alderfer, L.; Neu, E.; Saha, S.; Johandes, E.; Haas, D. M.; Haneline, L.; Hanjaya-Putra, D.
10.1101/2023.12.03.569585 — bioengineering — Posted on 2023-12-05
3949 Whole-genome sequences reveal zygotic composition in chimeric twins
Yoon, C. J.; Nam, C. H.; Kim, T.; Lee, J. S.; Yi, K.; Kim, R.; Koh, J.-Y.; Kim, J.; Won, H.; Oh, J.; Griffith, O. L.; Griffith, M.; Sung, J.; Kim, T. Y.; Choi, J. S.; Cho, D.; Ju, Y. S.
10.1101/2023.12.03.568663 — genomics — Posted on 2023-12-05
3950 Chloroplast genome-based genetic resources for Japan's threatened subalpine forests via genome skimming
Worth, J. R. P.; Kikuchi, S.; Kanetani, S.; Takahashi, D.; Aizawa, M.; Marchuk, E. A.; Choi, H.-J.; Polezhaeva, M. A.; Sheiko, V. V.; Ueno, S.
10.1101/2023.12.03.569577 — genetics — Posted on 2023-12-05
3951 Coevolution of longevity and female care of male gametes
Baur, J.; Koppik, M.; Savkovic, U.; Dordevic, M.; Stojkovic, B.; Berger, D.
10.1101/2023.12.03.569746 — evolutionary biology — Posted on 2023-12-05
3952 Effects of greening-induced warming and cooling on tree phenology in temperate and boreal forests
Guo, J.; Wang, J.; Qiao, Y.; Smith, N. G.; Liu, Z.; Zhang, R.; Chen, X.; Wu, C.; Chen, L.
10.1101/2023.12.03.569807 — ecology — Posted on 2023-12-05
3953 Seabird traits and seasonality modulate nutrient dynamics of terrestrial and marine habitats on atolls
Appoo, J.; Bunbury, N.; Letori, J.; Hector, A.; Gendron, A.; Graham, N. A.; Rocamora, G.; Lecorre, M.; Jaquemet, S.
10.1101/2023.12.03.569819 — ecology — Posted on 2023-12-05
3956 E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes.
Fu, C.; Dilasser, F.; Lin, S.-Z.; Karnat, M.; Arora, A.; Rajendiran, H.; Ong, H. T.; Hoon, N. M.; Phow, S. W.; Hirashima, T.; Sheezt, M.; Rupprecht, J.-F.; Tlili, S.; Viasnoff, V.
10.1101/2023.12.04.570034 — cell biology — Posted on 2023-12-05
3959 ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function
Ha, K.; Loeb, G. B.; Park, M.; Pinedo, A.; Park, C. H.; Brandes, N.; Ritu, F.; Ye, C. J.; Reiter, J. F.; Delling, M.
10.1101/2023.12.04.570035 — cell biology — Posted on 2023-12-05
3960 Spatial and Temporal Coordination of Force-generating Actin-based Modules Drives Membrane Remodeling In Vivo
Heydecker, M.; Shitara, A.; Chen, D.; Tran, D.; Masedunskas, A.; Tora, M.; Ebrahim, S.; Appaduray, M. A.; Galeano Nino, J. L.; Bhardwaj, A.; Narayan, K.; Hardeman, E. C.; Gunning, P.; Weigert, R.
10.1101/2023.12.04.569944 — cell biology — Posted on 2023-12-05
3962 Imaging neuronal voltage beyond the scattering limit
Chen, T.-W.; Huang, X.-B.; Plutkis, S. E.; Holland, K. L.; Lavis, L. D.; Lin, B.-J.
10.1101/2023.12.03.568403 — neuroscience — Posted on 2023-12-05
3965 Yeast9: A Consensus Yeast Metabolic Model Enables Quantitative Analysis of Cellular Metabolism By Incorporating Big Data
Zhang, C.; Sanchez, B. J.; Li, F.; Eiden, C. W. Q.; Scott, W. T.; Liebal, U. W.; Blank, L. M.; Mengers, H. G.; Anton, M.; Rangel, A. T.; Mendoza, S. N.; Zhang, L.; Nielsen, J.; Lu, H.; Kerkhoven, E. J.
10.1101/2023.12.03.569754 — systems biology — Posted on 2023-12-05
3971 Towards A Wireless Image Sensor for Real-Time Fluorescence Microscopy in Cancer Therapy
Rabbani, R.; Najafiaghdam, H.; Roschelle, M. L.; Papageorgiou, E. P.; Zhao, B. R.; Ghanbari, M. M.; Muller, R.; Stojanovic, V.; Anwar, M.
10.1101/2023.12.03.569779 — bioengineering — Posted on 2023-12-05
3972 The effects of alternative rabbit control methods on feral cat activity in an open, semi-arid landscape
Jansen, J.; Comte, S.; Dean, A. T.; Axford, G.; Moseby, K. E.; Peacock, D. E.; Brandle, R.; Jones, M. E.
10.1101/2023.12.03.569789 — ecology — Posted on 2023-12-05
3973 Spatial niche separation of an invasive and a native mesopredator
Jansen, J.; Moseby, K.; Comte, S.; Dean, A. T.; Axford, G.; Peacock, D. E.; Brandle, R.; Jones, M. E.
10.1101/2023.12.03.569481 — ecology — Posted on 2023-12-05
3974 Non-canonical NF-κB signaling in dendritic cells promotes intestinal inflammation by restraining the tolerogenic β-catenin-Raldh2 axis
Deka, A.; Kumar, N.; Chawla, M.; Bhattacharya, N.; Ali, A. S.; Basu, S.; Bhawna, ; Madan, U.; Kumar, S.; Das, B.; Sengupta, D.; Awasthi, A.; Basak, S.
10.1101/2023.12.03.569755 — immunology — Posted on 2023-12-05
3975 Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells
Conti, S.; Venturini, V.; Canellas-Socias, A.; Cortina, C.; Abenza, J. F.; Attolini, C. S.-O.; Guerra, E. M.; Xu, C. K.; Li, J. H.; Rossetti, L.; Stassi, G.; Roca-Cusachs, P.; Diz-Munoz, A.; Ruprecht, V.; Guck, J.; Batlle, E.; Labernadie, A.; Trepat, X.
10.1101/2023.12.04.569244 — cancer biology — Posted on 2023-12-05
3976 Estimation of the mass density of biological matter from refractive index measurements
Moeckel, C.; Beck, T.; Kaliman, S.; Abuhattum, S.; Kim, K.; Kolb, J.; Wehner, D.; Zaburdaev, V.; Guck, J.
10.1101/2023.12.05.569868 — biophysics — Posted on 2023-12-05
3981 Neutron capture enhances dose and reduces cancer cell viability in and out of beam during helium and carbon ion therapy.
Howell, N.; Middleton, R.; Sierro, F.; Wyatt, N.; Chacon, A.; Fraser, B.; Bamberry, K.; Livio, E.; Dobie, C.; Bevitt, J. J.; Davies, J.; Dosseto, A.; Franklin, D. R.; Garbe, U.; Guatelli, S.; Hirayma, R.; Matsufuji, N.; Mohammadi, A.; Mutimer, K.; Rendina, L.; Rosenfeld, A.; Safavi-Naeini, M.
10.1101/2023.12.03.569810 — biophysics — Posted on 2023-12-05
3983 Membrane fusion activity of herpes simplex virus 1 glycoproteins from a hyperfusogenic virus
Gianopulos, K. A.; Makio, A.; Pritchard, S. M.; Cunha, C.; Hull, M.; Nicola, A. V.
10.1101/2023.12.04.569993 — microbiology — Posted on 2023-12-05
3984 Fast imaging of millimeter-scale areas with beam deflection transmission electron microscopy
Zheng, Z.; Own, C. S.; Wanner, A. A.; Koene, R. A.; Hammerschmith, E. W.; Silversmith, W. M.; Kemnitz, N.; Lu, R.; Tank, D. W.; Seung, H. S.
10.1101/2022.11.23.517701 — neuroscience — Posted on 2023-12-05
3988 Satellite glial GPR37L1 regulates maresin and potassium channel signaling for pain control
Bang, S.; Jiang, C.; Xu, J.; Chandra, S.; Mcginnis, A.; Luo, X.; He, Q.; Li, Y.; Wang, Z.; Ao, X.; Parisien, M.; de Araujo, L. O.; Esfahan, S. J.; Zhang, Q.; Tonello, R.; Berta, T.; Diatchenko, L.; Ji, R.-R.
10.1101/2023.12.03.569787 — neuroscience — Posted on 2023-12-05
3989 Advancing childhood cancer research through young investigator and advocate collaboration
Weiner, A. K.; Palmer, A.; Moll, M. F.; Lindberg, G.; Reidy, K.; Diskin, S. J.; Mackall, C. L.; Maris, J. M.; Sullivan, P. J.
10.1101/2023.12.03.569769 — scientific communication and education — Posted on 2023-12-05
3993 VDAC1 selective molecules promote patients-derived cancer organoids death through mitochondrial-dependent metabolic interference
Conti Nibali, S.; De Siervi, S.; Magri, A.; Brocca, L.; Mantovani, S.; Oliviero, B.; Mondelli, M. U.; De Pinto, V.; Turato, C.; Arrigoni, C.; Lolicato, M.
10.1101/2023.12.04.569205 — biophysics — Posted on 2023-12-05
3994 DeePNAP: A deep learning method to predict protein-nucleic acids binding affinity from sequence
Pandey, U.; Behara, S. M.; Sharma, S.; Patil, R. S.; Nambiar, S.; Koner, D.; Bhukya, H.
10.1101/2023.12.03.569768 — biophysics — Posted on 2023-12-05
4004 Proteomic and Physiological Signatures of Altitude Adaptation in a Myrsine coriacea Population under Common Garden Conditions
Paschoa, R. P.; Pinto, V. B.; Pereira, J. P.; Cavatte, P. C.; Garbin, M. L.; Godinho, T. d. O.; Xavier, L. R.; Carrijo, T. T.; Silveira, V.
10.1101/2023.12.01.569649 — plant biology — Posted on 2023-12-05
4005 Coenzyme-Protein Interactions since Early Life
Sanchez Rocha, A. C.; Makarov, M.; Pravda, L.; Novotny, M.; Hlouchova, K.
10.1101/2023.10.28.563965 — bioinformatics — Posted on 2023-12-05
4007 NanoPyx: super-fast bioimage analysis powered by adaptive machine learning
Saraiva, B. M.; Cunha, I. M.; Brito, A. D.; Follain, G.; Portela, R.; Haase, R.; Pereira, P. M.; Jacquemet, G.; Henriques, R.
10.1101/2023.08.13.553080 — bioinformatics — Posted on 2023-12-05
4008 Combining environmental DNA and remote sensing for efficient, fine-scale mapping of arthropod biodiversity
Li, Y.; Devenish, C.; Tosa, M.; Luo, M.; Bell, D.; Lesmeister, D.; Greenfield, P.; Pichler, M.; Levi, T.; Yu, D. W.
10.1101/2023.09.07.556488 — ecology — Posted on 2023-12-05
4010 Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space
Lolicato, F.; Steringer, J.; Saleppico, R.; Beyer, D.; Fernandez-Sobaberas, J.; Unger, S.; Klein, S.; Riegerova, P.; Schmitt, X. J.; Kaptan, S.; Wegehingel, S.; Mueller, H.-M.; Freund, C.; Hof, M.; Sachl, R.; Chlanda, P.; Vattulainen, I.; Nickel, W.
10.1101/2023.04.12.536539 — biochemistry — Posted on 2023-12-05
4012 Prediction of tumor-specific splicing from somatic mutations as a source of neoantigen candidates
Lang, F.; Sorn, P.; Suchan, M.; Henrich, A.; Albrecht, C.; Koehl, N.; Beicht, A.; Riesgo-Ferreiro, P.; Holtsträter, C.; Schrörs, B.; Weber, D.; Löwer, M.; Sahin, U.; Ibn-Salem, J.
10.1101/2023.06.27.546494 — bioinformatics — Posted on 2023-12-05
4013 Responses of the hyper-diverse community of canopy-dwelling Hymenoptera to oak decline
Le Souchu, E.; Cours, J.; Cochenille, T.; Bouget, C.; Bankhead-Dronnet, S.; Braet, Y.; Burguet, P.; Gabard, C.; Galkowski, C.; Gereys, B.; Herbrecht, F.; Joncour, B.; Marhic, E.; Michez, D.; Buhl, P. N.; Noblecourt, T.; Notton, D. G.; Penigot, W.; Rasplus, J.-Y.; Robert, T.; Staverlokk, A.; Vincent-Barbaroux, C.; Salle, A.
10.1101/2023.07.25.550070 — ecology — Posted on 2023-12-05
4014 MARK1 regulates dendritic spine morphogenesis and cognitive functions in vivo
Kelly-Castro, E. C.; Shear, R.; Dindigal, A. H.; Bhagwat, M.; Zhang, H.
10.1101/2023.12.03.569757 — neuroscience — Posted on 2023-12-05
4019 Spatiotemporal brain hierarchies of auditory memory recognition and predictive coding
Bonetti, L.; Fernandez-Rubio, G.; Carlomagno, F.; Dietz, M. J.; Pantazis, D.; Vuust, P.; Kringelbach, M. L.
10.1101/2022.11.19.517195 — neuroscience — Posted on 2023-12-05
4020 The SCN8A p.(Gly1625Arg) variant associated with developmental and epileptic encephalopathy causes complex biophysical changes and reduced neuronal firing
Quinn, S.; Zhang, N.; Fenton, T. A.; Brusel, M.; Muruganandam, P.; Peleg, Y.; Giladi, M.; Haitin, Y.; Lerche, H.; Bassan, H.; Liu, Y.; Ben-Shalom, R.; Rubinstein, M.
10.1101/2023.12.04.569940 — physiology — Posted on 2023-12-05
4021 Cell-type-specific 3D-genome organization and transcription regulation in the brain
Liu, S.; Zheng, P.; Wang, C. Y.; Jia, B. B.; Zemke, N. R.; Ren, B.; Zhuang, X.
10.1101/2023.12.04.570024 — biophysics — Posted on 2023-12-05
4022 Isogenic iPSC-derived proximal and distal lung-on-chip models: Tissue- and virus-specific immune responses in human lungs
Yadav, S.; Fujimoto, K.; Takenaga, T.; Takahashi, S.; Muramoto, Y.; Mikawa, R.; Noda, T.; Gotoh, S.; Yokokawa, R.
10.1101/2023.11.24.568532 — bioengineering — Posted on 2023-12-05
4023 Characterization of cortical neurodevelopment in vitro using gene expression and morphology profiles from single cells
Sundaresh, A.; Meistermann, D.; Lampela, R.; Yang, Z.; Woldegebriel, R.; Ganna, A.; Costa, P. P.; Kilpinen, H.
10.1101/2023.12.03.569583 — genomics — Posted on 2023-12-05
4025 Plasticity of gene expression in the nervous system by exposure to environmental odorants that inhibit HDACs
Haga-Yamanaka, S.; Nunez-Flores, R.; Scott, C. A.; Perry, S.; Chen, S. T.; Pontrello, C.; Nair, M. G.; Ray, A.
10.1101/2023.02.21.529339 — neuroscience — Posted on 2023-12-04
4026 Spatially resolved molecular and cellular atlas of the mouse brain
Han, L.; Liu, Z.; Jing, Z.; Liu, Y.; Chang, H.; Lei, J.; Peng, Y.; Wang, K.; Xu, Y.; Liu, W.; Wu, Z.; Li, Q.; Shi, X.; Zheng, M.; Wang, H.; Deng, J.; Zhong, Y.; Pan, H.; Lin, J.; Zhang, R.; Chen, Y.; Wu, J.; Xu, M.; Ren, B.; Cheng, M.; Yu, Q.; Song, X.; Lu, Y.; Tang, Y.; Yuan, N.; Sun, S.; An, Y.; Ding, W.; Sun, X.; Wei, Y.; Zhang, S.; Dou, Y.; Zhao, Y.; Han, L.; Zhu, Q.; Xu, J.; Wang, S.; Chen, H.; Wang, D.; Bai, Y.; Liang, Y.; Liu, Y.; Chen, M.; Xie, C.; Bo, B.; Li, M.; Zhang, X.; Ting, W.; Chen, Z.; Fang, J.; Li, S.; Jiang, Y.; Tan, X.; Zuo, G.; Xie, Y.; Li, H.; Tao, Q.; Li, Y.; Liu, J.; Li
10.1101/2023.12.03.569501 — neuroscience — Posted on 2023-12-05
4028 Open-top Bessel beam two-photon light sheet microscopy for three-dimensional pathology
Park, W. Y.; Yun, J.; Shin, J.; Oh, B. H.; Yoon, G.; Hong, S.-M.; Kim, K. H.
10.1101/2023.10.18.562941 — pathology — Posted on 2023-12-04
4029 Dual Recognition of Multiple Signals in Bacterial Outer Membrane Proteins Enhance Assembly and Maintain Membrane Integrity
Germany, E. M.; Thewasano, N.; Imai, K.; Maruno, Y.; Bamert, R. S.; Stubenrauch, C. J.; Dunstan, R. A.; Ding, Y.; Nakajima, Y.; Lai, X.; Webb, C. T.; Hidaka, K.; Tan, K. S.; Shen, H.-H.; Lithgow, T.; Shiota, T.
10.1101/2021.10.29.466387 — biochemistry — Posted on 2023-12-04
4031 Single-cell RNA sequencing implicates venous endothelial cells as a source of VEGF-A-mediated neo-angiogenesis in neuroinflammation
Shahriar, S.; Biswas, S.; Zhao, K.; Akcan, U.; Tuohy, M. C.; Glendinning, M. D.; Kurt, A.; Wayne, C. R.; Prochilo, G.; Price, M. Z.; Brekken, R. A.; Menon, V.; Agalliu, D.
10.1101/2022.11.15.516660 — neuroscience — Posted on 2023-12-04
4032 Neuronal "parts list" and wiring diagram for a visual system
Matsliah, A.; Yu, S.-c.; Kruk, K.; Bland, D.; Burke, A.; Gager, J.; Hebditch, J.; Silverman, B.; Willie, K.; Willie, R.; Sorek, M.; Sterling, A. R.; Kind, E.; Garner, D.; Sancer, G.; Wernet, M.; Kim, S. S.; Murthy, M.; Seung, H. S.; FlyWire Consortium,
10.1101/2023.10.12.562119 — neuroscience — Posted on 2023-12-04
4033 A foundational atlas of autism protein interactions reveals molecular convergence
Wang, B.; Vartak, R.; Zaltsman, Y.; Naing, Z. Z. C.; Hennick, K. M.; Polacco, B. J.; Bashir, A.; Eckhardt, M.; Bouhaddou, M.; Xu, J.; Sun, N.; Lasser, M.; Zhou, Y.; Guiley, K. Z.; Chan, U.; Kaye, J. A.; Khare, P.; Drake, S.; Drury, V.; Burke, D. F.; Gonzalez, S.; Alkhairy, S.; Morris, M.; Baum, T.; Krasnoff, R.; Wang, S.; Pham, P.; Arbalaez, J.; Pratt, D.; Chag, S.; Rolland, T.; Bourgeron, T.; Finkbeiner, S.; Bandyopadhay, S.; Ideker, T.; Beltrao, P.; Willsey, H. R.; Obernier, K.; Nowakowski, T. J.; Huttenhain, R.; State, M. W.; Willsey, A. J.; Krogan, N. J.
10.1101/2023.12.03.569805 — systems biology — Posted on 2023-12-04
4034 Plant diversity darkspots for global collection priorities
Ondo, I.; Dhanjal-Adams, K.; Pironon, S.; Silvestro, D.; Colli-Silva, M.; Deklerck, V.; Grace, O.; Monro, A. K.; Nicolson, N.; Walker, B.; Antonelli, A.
10.1101/2023.09.12.557387 — plant biology — Posted on 2023-12-04
4038 Structural basis of the mechanism and inhibition of a human ceramide synthase
Pascoa, T. C.; Pike, A. C. W.; Tautermann, C. S.; Chi, G.; Traub, M.; Quigley, A.; Chalk, R.; Stefanic, S.; Thamm, S.; Pautsch, A.; Carpenter, E. P.; Schnapp, G.; Sauer, D. B.
10.1101/2023.12.02.569723 — biochemistry — Posted on 2023-12-04
4040 Determinants of spring migration departure dates in a New World sparrow: weather variables reign supreme
Byrd, A. J.; Talbott, K. M.; Smiley, T. M.; Verrett, T. B.; Gross, M.; Hladik, M. L.; Ketterson, E. D.; Becker, D.
10.1101/2023.11.17.567563 — ecology — Posted on 2023-12-04
4041 High-Throughput Screening of the Effects of 90 Xenobiotics on the Simplified Human Gut Microbiota Model (SIHUMIx): A Metaproteomic and Metabolomic Study
Castaneda-Monsalve, V.; Froehlich, L.-F.; Haange, S.-B.; Homsi, M. N.; Rolle-Kampczyk, U.; Fu, Q.; von Bergen, M.; Jehmlich, N.
10.1101/2023.12.04.569900 — molecular biology — Posted on 2023-12-04
4046 Supercomputer framework for reverse engineering firing patterns of neuron populations to identify their synaptic inputs
Chardon, M. K.; Wang, Y. C.; Garcia, M.; Besler, E.; Beauchamp, J. A.; D'Mello, M.; Powers, R. K.; Heckman, C. J.
10.1101/2022.12.09.519818 — neuroscience — Posted on 2023-12-04
4048 Comparison of the mechanism of antimicrobial action of the gold(I) compound auranofin in Gram-positive and Gram-negative bacteria
Quadros Barse, L.; Ulfig, A.; Varatnitskaya, M.; Vazquez-Hernandez, M.; Yoo, J.; Imann, A. M.; Lupilov, N.; Becker, K.; Fischer, M.; Bandow, J. E.; Leichert, L. I.
10.1101/2023.12.04.569911 — biochemistry — Posted on 2023-12-04
4049 Cdc13 exhibits dynamic DNA strand exchange in the presence of telomeric DNA
Nickens, D. G.; Feng, Z.; Shen, J.; Simmons, R. H.; Niu, H.; Bochman, M. L.
10.1101/2023.12.04.569902 — biochemistry — Posted on 2023-12-04
4050 Reversing the decline of threatened koala (Phascolarctos cinereus) populations in New South Wales: Using genomics to define meaningful conservation goals
Lott, M. J.; Frankham, G. J.; Eldridge, M. D. B.; Alquezar-Planas, D. E.; Donnelly, L.; Zenger, K. R.; Leigh, K. A.; Kjeldsen, S. R.; Field, M. A.; Lemon, J.; Lunney, D.; Crowther, M. S.; Krockenberger, M. B.; Fisher, M.; Neaves, L. E.
10.1101/2023.12.03.569474 — genomics — Posted on 2023-12-04
4051 Identification of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir
Krismer, L.; Schoeppe, H.; Rauch, S.; Bante, D.; Sprenger, B.; Naschberger, A.; Costacurta, F.; Fuerst, A.; Sauerwein, A.; Rupp, B.; Kaserer, T.; von Laer, D.; Heilmann, E.
10.1101/2023.12.04.569917 — molecular biology — Posted on 2023-12-04
4052 Homologous recombination contributes to the repair of acetaldehyde-induced DNA damages.
Yamazaki, K.; Takayasu, K.; Ngo, T. T. T.; Onuki, A.; Kawaji, H.; Oshima, S.; Kanda, T.; Masai, H.; Sasanuma, H.
10.1101/2023.12.03.569808 — molecular biology — Posted on 2023-12-04
4053 Predicting the dynamic interaction between intrinsically disordered proteins
Zheng, Y.; Li, Q.; Freiberger, M. I.; Song, H.; Hu, G.; Zhang, M.; Gu, R.; Li, J.
10.1101/2023.12.04.569847 — molecular biology — Posted on 2023-12-04
4054 Membrane specificity of the human cholesterol transfer protein STARD4
Talandashti, R.; van Ek, L.; Gehin, C.; Xue, D.; Moqadam, M.; Gavin, A.-C.; Reuter, N.
10.1101/2023.12.04.569895 — molecular biology — Posted on 2023-12-04
4055 Editing of highly homologous gamma-globin genes by nickase deficient Base Editor mitigates large intergenic deletions
George, A.; Ravi, N. S.; Babu, V.; Marepally, S.; Thangavel, S.; Velayudhan, S. R.; Srivastava, A.; Mohankumar, K. M.
10.1101/2023.12.04.569931 — molecular biology — Posted on 2023-12-04
4061 Global analysis of the RNA-RNA interactome in Acinetobacter baumannii AB5075 uncovers a small regulatory RNA repressing the virulence-related outer membrane protein CarO
Hamrock, F. J.; Ryan, D.; Shaibah, A.; Ershova, A. S.; Mogre, A.; Sulimani, M. M.; Reichardt, S.; Hokamp, K.; Westermann, A. J.; Kröger, C.
10.1101/2023.12.04.569942 — microbiology — Posted on 2023-12-04
4063 Alternative splicing expands the antiviral IFITM repertoire in Chinese horseshoe bats
Mak, N.; Zhang, D.; Li, X.; Rahman, K.; Datta, S. A. K.; Taylor, J.; Liu, J.; Shi, Z.; Temperton, N.; Irving, A. T.; Compton, A. A.; Sloan, R. D.
10.1101/2023.12.04.569605 — microbiology — Posted on 2023-12-04
4064 Beyond defense: Glucosinolate structural diversity shapes recruitment of a metabolic network of leaf-associated bacteria
Unger, K.; Raza, S. A. K.; Mayer, T.; Reichelt, M.; Stuttmann, J.; Hielscher, A.; Wittstock, U.; Gershenzon, J.; Agler, M. T.
10.1101/2023.12.04.567830 — microbiology — Posted on 2023-12-04
4065 Armillaria korhonenii, the sixteenth biological species of Armillaria from China
Liu, J.; Qin, G.; Chen, J.; Song, J.; Yan, Z.; Yang, S.; Tian, M.-h.; Xu, X.; Zhang, C.; Luangharn, T.; Bhunjun, C. S.; Yu, F.; Yang, Z.
10.1101/2023.12.04.569844 — microbiology — Posted on 2023-12-04
4066 Temperament in early childhood is associated with gut microbiota composition and diversity
Ueda, E.; Matsunaga, M.; Fujihara, H.; Kajiwara, T.; Takeda, A. K.; Watanabe, S.; Hagihara, K.; Myowa, M.
10.1101/2023.12.03.569811 — microbiology — Posted on 2023-12-04
4067 Viruses that 'infect' viruses: Cas12f1 and Cas9 gene drive in HSV1
Dai, H.; Yao, Q.; Lin, Z.; Lai, K.; Zeng, X.; Lei, G.; Zhang, T.
10.1101/2023.12.04.569968 — microbiology — Posted on 2023-12-04
4074 Structural basis for inhibition of βFXIIa by garadacimab
Drulyte, I.; Ghai, R.; Ow, S. Y.; Kapp, E.; Quek, A.; Panousis, C.; Wilson, M. J.; Nash, A. D.; Pelzing, M.
10.1101/2023.12.03.569829 — biochemistry — Posted on 2023-12-04
4078 ISWI catalyzes nucleosome sliding in condensed nucleosome arrays
Vizjak, P.; Kamp, D.; Hepp, N.; Scacchetti, A.; Gonzalez Pisfil, M.; Bartho, J.; Halic, M.; Becker, P. B.; Smolle, M. M.; Stigler, J.; Muler-Planitz, F.
10.1101/2023.12.04.569516 — biochemistry — Posted on 2023-12-04
4083 Biolearn, an open-source library for biomarkers of aging
Ying, K.; Paulson, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.
10.1101/2023.12.02.569722 — bioinformatics — Posted on 2023-12-04
4084 External validation of machine learning models - registered models and adaptive sample splitting
Gallitto, G.; Englert, R.; Kincses, B.; Kotikalapudi, R.; Li, J.; Bingel, U.; Spisak, T.
10.1101/2023.12.01.569626 — bioinformatics — Posted on 2023-12-04
4086 In field use of water samples for genomic surveillance of ISKNV infecting tilapia fish in Lake Volta, Ghana
Alathari, S.; Joseph, A.; Bolanos, L. M.; Studholme, D.; Jeffries, A.; Appenteng, P.; Duodu, K.; Sawyerr, E.; Paley, R.; Tyler, C. R.; Temperton, B.
10.1101/2023.12.02.569710 — genomics — Posted on 2023-12-04
4090 Testis organ culture system capable of evaluating testicular toxicity
Hashimoto, K.; Arakawa, H.; Imamura, R.; Nishimura, T.; Kitajima, S.; Sato, T.; Makiyama, K.; Ogawa, T.; Yokota, S.
10.1101/2023.12.01.569566 — developmental biology — Posted on 2023-12-04
4093 An integrated transcriptomic cell atlas of human endoderm-derived organoids
Xu, Q.; Halle, L.; Hediyeh-zadeh, S.; Kuijs, M.; Kilik, U.; Yu, Q.; Frum, T.; Adam, L.; Parikh, S.; Gander, M.; Kfuri-Rubens, R.; Klein, D.; He, Z.; Fleck, J. S.; Oost, K.; Kahnwald, M.; Barbiero, S.; Mitrofanova, O.; Maciag, G.; Jensen, K. B.; Lutolf, M.; Liberali, P.; Beumer, J.; Spence, J. R.; Treutlein, B.; Theis, F. J.; Camp, J. G.
10.1101/2023.11.20.567825 — cell biology — Posted on 2023-12-04
4094 Single cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging and disease
Kilfeather, P.; Khoo, J. H.; Wagner, K.; Liang, H.; Caiazza, M.-C.; An, Y.; Zhang, X.; Chen, X.; Connor-Robson, N.; Shang, Z.; Wade-Martins, R.
10.1101/2023.04.20.537553 — molecular biology — Posted on 2023-12-04
4095 Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics
Dulyayangkul, P.; Beavis, T.; Lee, W. W.; Ardagh, R.; Edwards, F.; Hamilton, F.; Head, I.; Heesom, K. J.; Mounsey, O.; Murarik, M.; Reding, C.; Satapoomin, N.; Shaw, J. M.; Takebayashi, Y.; Tooke, C. L.; Spencer, J.; Williams, P. B.; Avison, M. B.
10.1101/2023.12.02.569715 — microbiology — Posted on 2023-12-04
4096 Gut bacteria-derived serotonin promotes immune tolerance in early life
Sanidad, K. Z.; Rager, S. L.; Carrow, H. C.; Ananthanarayanan, A.; Callaghan, R.; Ravisankar, P.; Li, T.; Savage, A. R.; Brown, J. A.; Amir, M.; Luo, R.; Mardorsky Rowdo, F.; Martin, M. L.; Silver, R. B.; Artis, D.; Hart, L. R.; Guo, C.-J.; Krumsiek, J.; Inohara, N.; Zeng, M. Y.
10.1101/2022.09.25.509428 — immunology — Posted on 2023-12-04
4097 An IL-2 mutein increases IL-10 and CTLA-4-dependent suppression of dendritic cells by regulatory T cells
Jamison, B. L.; Lawrance, M.; Wang, C. J.; DeBerg, H. A.; Sansom, D.; Gavin, M. A.; Walker, L. S. K.; Campbell, D. J.
10.1101/2023.12.01.569613 — immunology — Posted on 2023-12-04
4098 Innate extracellular Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors
Borges, T. J.; Lima, K.; Murshid, A.; Lape, I. T.; Zhao, Y.; Rigo, M. M.; Lang, B. J.; Siddiqui, S. S.; Hui, E.; Riella, L. V.; Bonorino, C.; Calderwood, S. K.
10.1101/2023.12.01.569623 — immunology — Posted on 2023-12-04
4099 Temporal Tracking of Plasma Cells in vivo Using J-chain CreERT2 Reporter System.
Borbet, T. C.; Zaldana, K.; Zavitsanou, A.-M.; Hines, M. J.; Bajwa, S.; Morrison, T.; Boehringer, T.; Hallisey, V. M.; Cadwell, K.; Koralov, S. B.
10.1101/2023.12.02.569736 — immunology — Posted on 2023-12-04
4101 Intermediate CA1 is Required for Object-in-Place Recognition Memory in Mice
Cruz-Sanchez, A.; Inayat, M.; Parikh, P.; Appings, R.; Violi, F.; Arruda-Carvalho, M.
10.1101/2023.12.01.569628 — neuroscience — Posted on 2023-12-04
4104 Spatially-resolved transcriptomics of human dentate gyrus across postnatal lifespan reveals heterogeneity in markers for proliferation, extracellular matrix, and neuroinflammation
Ramnauth, A. D.; Tippani, M.; Divecha, H. R.; Papariello, A. R.; Miller, R. A.; Pattie, E. A.; Kleinman, J. E.; Maynard, K. R.; Collado-Torres, L.; Hyde, T. M.; Martinowich, K.; Hicks, S. C.; Page, S. C.
10.1101/2023.11.20.567883 — neuroscience — Posted on 2023-12-04
4106 Brain network connectivity underlying remission in early psychosis: a whole brain model approach
Mana, L.; Lopez-Gonzalez, A.; Aleman Gomez, Y.; Baumann, P. S.; Jenni, R.; Alameda, L.; Abrahamyan Empson, L.; Klauser, P.; Conus, P.; Hagmann, P.; Vila Vidal, M.; Deco, G.
10.1101/2023.11.28.568844 — neuroscience — Posted on 2023-12-04
4108 Systems biology and machine learning approaches identify metabolites that influence dietary lifespan and healthspan responses across flies and humans.
Hilsabeck, T. A.; Narayan, V. P.; Wilson, K. A.; Carrera, E.; Raftery, D.; Promislow, D. E.; Brem, R. B.; Campisi, J. A.; Kapahi, P.
10.1101/2023.07.09.548232 — systems biology — Posted on 2023-12-04
4113 Cell wall extensin arabinosylation is required for root directional response to salinity
Zou, Y.; Gigli-Bisceglia, N.; van Zelm, E.; Kokkinopoulou, P.; Julkowska, M. M.; Besten, M.; Nguyen, T.-P.; Li, H.; Lamers, J.; De Zeeuw, T.; Dongus, J. A.; Zeng, Y.; Cheng, Y.; Koevoets, I. T.; Jorgensen, B.; Giesbers, M.; Vroom, J.; Ketelaar, T.; Petersen, B.; Engelsdorf, T.; Sprakel, J.; Zhang, Y.; Testerink, C.
10.1101/2022.06.22.497042 — plant biology — Posted on 2023-12-04
4115 Proteomic and Physiological Signatures of Altitude Adaptation in a Myrsine coriacea Population under Common Garden Conditions
Paschoa, R. P.; Pinto, V. B.; Pereira, J. P.; Cavatte, P. C.; Garbin, M. L.; Godinho, T. d. O.; Xavier, L. R.; Carrijo, T. T.; Silveira, V.
10.1101/2023.12.01.569649 — plant biology — Posted on 2023-12-04
4116 Age-related changes in human skeletal muscle transcriptome and proteome are moreaffected by chronic inflammation and physical inactivity than primary aging
Kurochkina, N. S.; Orlova, M. A.; Vigovskiy, M. A.; Vepkhvadze, T. F.; Zgoda, V. G.; Vavilov, N. E.; Makhnovskii, P. A.; Grigorieva, O. A.; Boroday, Y. R.; Philippov, V. V.; Lednev, E. M.; Efimenko, A. Y.; Popov, D. V.
10.1101/2023.12.01.569524 — physiology — Posted on 2023-12-04
4117 A High-Throughput Microphysiological Liver Chip System to Model Direct and Idiosyncratic Drug-Induced Liver Injury Using Human Liver Organoids
Zhang, C. J.; Meyer, S. R.; Garcia, M. A.; Procario, M. C.; Yoo, S.; Jolly, A. L.; Kim, S.; Kim, J.; Baek, K.; Kersten, R. D.; Fontana, R. J.; Sexton, J. Z.
10.1101/2023.12.01.569575 — pharmacology and toxicology — Posted on 2023-12-04
4120 Tumor microenvironmental determinants of high-risk DCIS progression
Glencer, A.; Ramalingam, K.; Schindler, N.; Mori, H.; Ghule, P.; Lee, K. C.; Nachmanson, D.; Officer, A.; Harismendy, O.; Stein, J. L.; Stein, G.; Weaver, D.; Yau, C.; Hirst, G. L.; Campbell, M. J.; Esserman, L. J.; Borowsky, A. D.
10.1101/2023.12.01.569676 — cancer biology — Posted on 2023-12-04
4121 Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma
Wasko, U. N.; Jiang, J.; Garcia, A. C.; Wang, Y.; Lee, B.; Orlen, M.; Drizyte-Miller, K.; Menard, M.; Dilly, J.; Sastra, S. A.; Palermo, C. F.; Dalton, T.; Hasselluhn, M. C.; Decker-Farrell, A. R.; Chang, S.; Jiang, L.; Wei, X.; Yang, Y.-c.; Helland, C.; Courtney, H.; Gindin, Y.; Zhao, R.; Kemp, S. B.; Clendenin, C.; Sor, R.; Vostrejs, W.; Amparo, A. A.; Hibshman, P. S.; Rees, M. G.; Ronan, M. M.; Roth, J. A.; Bakir, B.; Badgley, M. A.; Chabot, J. A.; Kluger, M. D.; Manji, G. A.; Quintana, E.; Wang, Z.; Smith, J. A. M.; Holderfield, M.; Wildes, D.; Aguirre, A. J.; Der, C. J.; Vonderheide, R. H
10.1101/2023.12.03.569791 — cancer biology — Posted on 2023-12-04
4122 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signaling in the tumour microenvironment
Mukherjee, A. K.; Dutta, S.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Chatterjee, M.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; Sengupta, V.; Perwez, A.; George, N.; Faruq, M.; Gupta, I.; Sabarinathan, R.; Chowdhury, S.
10.1101/2021.12.07.471419 — cancer biology — Posted on 2023-12-04
4123 VGLL1 drives therapy resistance in estrogen receptor positive breast cancer
Gemma, C.; Lai, C.; Singh, A.; Belfiore, A.; Portman, N.; Milioli, H. Z.; Periyasamy, M.; Abuelmaaty, S.; Nicholls, A. J.; Davies, C.; Patel, N. R.; Simmons, G.; Fan, H.; Nguyen, V.; Magnani, L.; Rakha, E.; Martin, L.-A.; Lim, E.; Coombes, C.; Pruneri, G.; Buluwela, L.; Ali, S.
10.1101/2020.11.29.402842 — cancer biology — Posted on 2023-12-04
4125 Contrasting Sequence with Structure: Pre-training Graph Representations with PLMs
Robinson, L. C. B.; Atkinson, T.; Copoiu, L.; Bordes, P.; Pierrot, T.; Barrett, T.
10.1101/2023.12.01.569611 — bioinformatics — Posted on 2023-12-04
4127 Contextualized Networks Reveal Heterogeneous Transcriptomic Regulation in Tumors at Sample-Specific Resolution
Ellington, C. N.; Lengerich, B. J.; Watkins, T. B.; Yang, J.; Xiao, H.; Kellis, M.; Xing, E. P.
10.1101/2023.12.01.569658 — bioinformatics — Posted on 2023-12-04
4128 Deep Learning-based structural and functional annotation of Pandoravirus hypothetical proteins
Horder, J. L.; Connor, A. J.; Duggan, A. L.; Hale, J. J.; McDermott, F. J.; Norris, L. E.; Whinney, S. J.; Mesdaghi, S.; Murphy, D. L.; Simpkin, A. J.; Mello, L. V.; Rigden, D.
10.1101/2023.12.02.569716 — bioinformatics — Posted on 2023-12-04
4129 Image-based force inference by biomechanical simulation
Vanslambrouck, M.; Thiels, W.; Vangheel, J.; Smeets, B.; Jelier, R.
10.1101/2023.12.01.569682 — bioinformatics — Posted on 2023-12-04
4131 Towards the Clinical Translation of a Silver Sulfide Nanoparticle Contrast Agent: Large Scale Production with a Highly Parallelized Microfluidic Chip
Mossburg, K. J.; Shepherd, S. J.; Barragan, D.; O, N. H.; Berkow, E. K.; Maidment, P. S. N.; Rosario Berrios, D. N.; Hsu, J. C.; Siedlick, M. J.; Yadavali, S.; Mitchell, M. J.; Issadore, D.; Cormode, D. P.
10.1101/2023.12.02.569706 — bioengineering — Posted on 2023-12-04
4133 The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm?
Sreenivasan, S.; Heffren, P.; Suh, K.-S.; Rodnin, M. V.; Kosa, E.; Fenton, A. W.; Ladokhin, A.; Smith, P. E.; Fontes, J. D.; Swint-Kruse, L.
10.1101/2023.11.02.565367 — biochemistry — Posted on 2023-12-04
4136 Systematic comparison of sequencing-based spatial transcriptomic methods
You, Y.; Fu, Y.; Li, L.; Zhang, Z.; Jia, S.; Lu, S.; Ren, W.; Liu, Y.; Xu, Y.; Liu, X.; Jiang, F.; Peng, G.; Kumar, A. S.; Ritchie, M. E.; Liu, X.; Tian, L.
10.1101/2023.12.03.569744 — genomics — Posted on 2023-12-04
4137 The evolution and convergence of mutation spectra across mammals
Talenti, A.; Wilkinson, T.; Morrison, L. J.; Prendergast, J. G.
10.1101/2023.12.02.569698 — genetics — Posted on 2023-12-04
4138 Aberrant expression prediction across human tissues
Hölzlwimmer, F. R.; Lindner, J.; Wagner, N.; Yepez, V. A.; Casale, F. P.; Gagneur, J.
10.1101/2023.12.04.569414 — genetics — Posted on 2023-12-04
4144 Environmental and ecological signals predict periods of nutritional stress for Eastern Australian flying fox populations.
Lagergren, J.; Ruiz-Aravena, M.; Becker, D. J.; Madden, W.; Ruytenberg, L.; Hoegh, A.; Han, B.; Peel, A. J.; Eby, P.; Jacobson, D.; Plowright, R. K.
10.1101/2023.12.01.569640 — ecology — Posted on 2023-12-04
4145 Breathing in sync: how a social behavior structures respiratory epidemic risk in bottlenose dolphins
Collier, M. A.; Jacoby, A.-M.; Foroughirad, V.; Patterson, E. M.; Krzyszczyk, E.; Wallen, M. M.; Miketa, M.; Karniski, C.; Wilkin, S.; Mann, J.; Bansal, S.
10.1101/2023.12.01.569646 — ecology — Posted on 2023-12-04
4148 AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
Zhang, H.; Raymundo, J.; Daly, K. E.; Zhu, W.; Senapati, B.; Marneros, A. G.
10.1101/2023.12.03.569763 — cell biology — Posted on 2023-12-04
4151 Tracer-based metabolomics for profiling nitric oxide metabolites in a 3D microvessel-on-a-chip model
Pandian, K.; Huang, L.; Junaid, A.; Harms, A. C.; van Zonneveld, A. J.; Hankemeier, T.
10.1101/2023.12.03.569402 — cell biology — Posted on 2023-12-04
4154 A Mitochondrial Inside-Out Iron-Calcium Signal Reveals Drug Targets for Parkinsons Disease
Bharat, V.; Durairaj, A. S.; Vanhauwaert, R.; Li, L.; Muir, C. M.; Chandra, S.; Kwak, C. S.; Le Guen, Y.; Nandakishore, P.; Hsieh, C.-H.; Rensi, S. E.; Altman, R.; Greicius, M. D.; Feng, L.; Wang, X.
10.1101/2022.10.30.513580 — cell biology — Posted on 2023-12-04
4157 Cortical Network Disruption is Minimal in Early Stages of Psychosis
Van Dyken, P. C.; MacKinley, M.; Khan, A. R.; Palaniyappan, L. C.
10.1101/2023.12.02.569728 — neuroscience — Posted on 2023-12-04
4158 Mild blast TBI raises gamma connectivity, EEG power, and reduces GABA interneuron density
May, H. G.; Tsikonofilos, K.; Donat, C. K.; Sastre, M.; Kozlov, A. S.; Sharp, D. J.; Bruyns-Haylett, M.
10.1101/2023.12.01.569541 — neuroscience — Posted on 2023-12-04
4160 An inducible genetic tool for tracking and manipulating specific microglial states in development and disease
Barclay, K. M.; Abduljawad, N.; Cheng, Z.; Kim, M. W.; Zhou, L.; Yang, J.; Rustenhoven, J.; Mazzitelli Perez, J.; Smyth, L.; Beatty, W.; Hou, J.; Saligrama, N.; Colonna, M.; Yu, G.; Kipnis, J.; Li, Q.
10.1101/2023.12.01.569597 — neuroscience — Posted on 2023-12-04
4162 Translating from mice to humans: using preclinical blood-based biomarkers for the prognosis and treatment of traumatic brain injury
Lisi, I.; Moro, F.; Mazzone, E.; Marklund, N.; Pischiutta, F.; Kobeissy, F.; Mao, X.; Corrigan, F.; Helmy, A.; Nasrallah, F.; Di Pietro, V.; Ngwenya, L.; Portela, L. V.; Semple, B. D.; Smith, D. H.; Wellington, C.; Loane, D.; Wang, K. K.; Zanier, E. R.; InTBIR Fundamental & Translational Working Group,
10.1101/2023.12.01.569152 — neuroscience — Posted on 2023-12-04
4163 Network-level encoding of local neurotransmitters in cortical astrocytes
Cahill, M. K.; Collard, M.; Tse, V.; Reitman, M. E.; Etchenique, R.; Kirst, C.; Poskanzer, K. E.
10.1101/2023.12.01.568932 — neuroscience — Posted on 2023-12-04
4165 Power-law growth models explain incidences and sizes of pancreatic cancer precursor lesions and confirm spatial genomic findings
Kiemen, A. L.; Wu, P.; Braxton, A. M.; Cornish, T. C.; Hruban, R. H.; Wood, L. D.; Wirtz, D.; Zwicker, D.
10.1101/2023.12.01.569633 — biophysics — Posted on 2023-12-04
4166 Evaluating polarizable biomembranesimulations against experiments
Kav, B.; Antila, H. S.; Dixit, S.; Miettinen, M. S.; Madsen, J. J.; Ollila, O. H. S.
10.1101/2023.12.01.569661 — biophysics — Posted on 2023-12-04
4167 Democratizing computational pathology: optimized Whole Slide Image representations for The Cancer Genome Atlas
Lazard, T.; Lerousseau, m.; Gardrat, S.; Vincent-Salomon, A.; Stern, M.-H.; Rodrigues, M.; Decenciere, E.; Walter, T.
10.1101/2023.12.04.569894 — bioinformatics — Posted on 2023-12-04
4168 Tuning of granulopoietic signaling by de novo designed agonists
Ullrich, T.; Pollmann, C.; Ritter, M.; Haaf, J.; Aghaallaei, N.; Tesakov, I.; El-Riz, M.; Maksymenko, K.; Hatskovska, V.; Kandabarau, S.; Klimiankou, M.; Lengerke, C.; Welte, K.; Hernandez Alvarez, B.; Müller, P.; Lupas, A. N.; Piehler, J.; Skokowa, J.; ElGamacy, M.
10.1101/2023.11.25.568662 — bioengineering — Posted on 2023-12-04
4170 Extensive remodelling of XIST regulatory networks during primate evolution
Cazottes, E.; Alfeghaly, C.; Rognard, C.; Loda, A.; Castel, G.; Villacorta, L.; Dong, M.; Heard, E.; Aksoy, I.; Savatier, P.; Morey, C.; Rougeulle, C.
10.1101/2023.12.04.569904 — genomics — Posted on 2023-12-04
4177 The immune landscape of the inflamed joint defined by spectral flow cytometry
Attrill, M. H.; Shinko, D.; Alexiou, V.; Kartawinata, M.; Wedderburn, L. R.; CHARMS study, ; JIAP study, ; Pesenacker, A. M.
10.1101/2023.11.30.569010 — immunology — Posted on 2023-12-04
4178 pan-MHC and cross-Species Prediction of T Cell Receptor-Antigen Binding
Han, Y.; Yang, Y.; Tian, Y.; Fattah, F. J.; Itzstein, M. S. v.; Zhang, M.; Kang, X.; Yang, D. M.; Liu, J.; Xue, Y.; Liang, C.; Raman, I.; Zhu, C.; Xiao, O.; Hu, Y.; Dowell, J. E.; Homsi, J.; Rashdan, S.; Yang, S.; Gwin, M. E.; Hsiehchen, D.; Gloria-McCutchen, Y.; Pan, K.; Wu, F.; Gibbons, D.; Wang, X.; Yee, C.; Huang, J.; Reuben, A.; Cheng, C.; Zhang, J.; Gerber, D. E.; Wang, T.
10.1101/2023.12.01.569599 — immunology — Posted on 2023-12-04
4180 A ketogenic diet reduces age-induced chronic neuroinflammation in mice
Nomura, M.; Murad, N. F.; Madhavan, S. S.; Eap, B.; Garcia, T. Y.; Aguirre, C. G.; Verdin, E.; Ellerby, L.; Furman, D.; Newman, J. C.
10.1101/2023.12.01.569598 — immunology — Posted on 2023-12-04
4182 Humans progressively feel agency over events triggered before their actions
Toma, M.; Mattout, J.; Quentin, R.; Rassoulou, F.; Gautier, A.; Maby, E.; Vernet, M.
10.1101/2023.12.01.569449 — neuroscience — Posted on 2023-12-04
4187 Inducing representational change in the hippocampus through real-time neurofeedback
Peng, K.; Wammes, J. D.; Nguyen, A.; Iordan, M. C.; Norman, K. A.; Turk-Browne, N. B.
10.1101/2023.12.01.569487 — neuroscience — Posted on 2023-12-04
4188 Atrophy-driven functional network collapse in neurodegenerative disease
Brown, J. A.; Lee, A. J.; Fernhoff, K.; Pistone, T.; Pasquini, L.; Wise, A. B.; Staffaroni, A. M.; Mandelli, M. L.; Lee, S. E.; Boxer, A. L.; Rankin, K. P.; Rabinovici, G. D.; Gorno-Tempini, M. L.; Rosen, H. J.; Kramer, J. H.; Miller, B. L.; Seeley, W. W.
10.1101/2023.12.01.569654 — neuroscience — Posted on 2023-12-04
4189 Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington's disease
Herrero-Lorenzo, M.; Perez-Perez, J.; Escaramis, G.; Martinez-Horta, S.; Perez-Gonzalez, R.; Rivas-Asensio, E.; Kulisevsky, J.; Gamez-Valero, A.; Marti, E.
10.1101/2023.12.01.568823 — neuroscience — Posted on 2023-12-04
4190 Higher seed yield through selection for reduced seed shattering in Italian ryegrass (Lolium multiflorum Lam.)
Kiesbauer, J.; Koelliker, R.; Hug, M.; Sindelar, M.; Schlatter, L. H.; Ohnmacht, J.; Studer, B.; Grieder, C.
10.1101/2023.12.01.569550 — plant biology — Posted on 2023-12-04
4192 Auxin Exposure Disrupts Feeding Behavior and Fatty Acid Metabolism in Adult Drosophila
Fleck, S. A.; Biswas, P.; DeWitt, E. D.; Knuteson, R. L.; Eisman, R. C.; Nemkov, T.; D'Alessandro, A.; Tennessen, J. M.; Rideout, E. J.; Weaver, L. N.
10.1101/2023.08.15.553385 — physiology — Posted on 2023-12-04
4193 UBE2N is essential for maintenance of skin homeostasis and suppression of inflammation
Lee, M. J.; Ben Hammouda, M.; Miao, W.; Okafor, A.; Jin, Y.; Sun, H.; Jain, V.; Markovtsov, V.; Diao, Y.; Gregory, S. G.; Zhang, J. Y.
10.1101/2023.12.01.569631 — pathology — Posted on 2023-12-04
4194 Balanced Permeability Index: a multi-parameter index for improved in-vitro permeability
Weiss, D. R.; Baylon, J. L.; Evans, E. D.; Paiva, A.; Everlof, G.; Cutrone, J.; Broccatelli, F.
10.1101/2023.12.01.569478 — bioinformatics — Posted on 2023-12-04
4197 Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered SARS-CoV-2 Spike Protein leading to Neutrophil Recruitment and Damage
Park, C.; Hwang, I.-Y.; Yan, S. L.-S.; Vimonpatranon, S.; Wei, D.; Van Ryk, D.; Girard, A.; Cicala, C.; Arthos, J.; Kehrl, J. H.
10.1101/2023.03.13.532446 — immunology — Posted on 2023-12-04
4199 Diversity of ribosomes at the level of rRNA variation associated with human health and disease
Rothschild, D.; Susanto, T. T.; Sui, X.; Spence, J. P.; Rangan, R.; Genuth, N. R.; Sinnott-Armstrong, N.; Wang, X.; Pritchard, J. K.; Barna, M.
10.1101/2023.01.30.526360 — genetics — Posted on 2023-12-04
4200 Haem's relevance genuine? Re-visiting the roles of TANGO2 homologues including HRG-9 and HRG-10 in C. elegans
Sandkuhler, S. E.; Youngs, K.; Owlett, L.; Bandora, M.; Naaz, A.; Kim, E. S.; Wang, L.; Wojtovich, A. P.; Gupta, V. A.; Sacher, M.; Mackenzie, S. J.
10.1101/2023.11.29.569072 — cell biology — Posted on 2023-12-04
4201 Gut microbiome remains stable following COVID-19 vaccination in healthy and immuno-compromised individuals
Boston, R. H.; Guan, R.; Kalmar, L.; Beier, S.; Horner, E. C.; Beristain-Covarrubias, N.; Yam-Puc, J. C.; Gerber, P. P.; Faria, L.; Kuroshchenkova, A.; Lindell, A. E.; Blasche, S.; Correa-Noguera, A.; Elmer, A.; Saunders, C.; Bermperi, A.; Jose, S.; Kingston, N.; COVID-19 BioResource Collaboration, ; Grigoriadou, S.; Staples, E.; Buckland, M.; Lear, S.; Matheson, N. J.; Benes, V.; Parkinson, C.; Thaventhiran, J. E.; Patil, K. R.
10.1101/2023.08.23.554506 — microbiology — Posted on 2023-12-04
4206 RNase T2-involved selective autophagy of ribosomes induced by starvation in yeast
Minami, A.; Nishi, K.; Yamada, R.; Jinnai, G.; Shima, H.; Oishi, S.; Akagawa, H.; Aono, T.; Hidaka, M.; Masaki, H.; Kuzuyama, T.; Noda, Y.; Ogawa, T.
10.1101/2023.07.14.548783 — molecular biology — Posted on 2023-12-04
4212 Synaptic and dendritic architecture of two types of hippocampal somatostatin interneurons
Takacs, V.; Bardoczi, Z.; Orosz, A.; Major, A.; Tar, L.; Berki, P.; Papp, P.; Mayer, M. I.; Sebok, H.; Zsolt, L.; Sos, K. E.; Kali, S.; Freund, T. F.; Nyiri, G.
10.1101/2023.05.14.540675 — neuroscience — Posted on 2023-12-04
4213 Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants.
Roth, O.; Yechezkel, S.; Serero, O.; Eliyahu, A.; Vints, I.; Tzeela, P.; Carignano, A.; Janacek, D. P.; Peters, V.; Kessel, A.; Dwivedi, V.; Carmeli-Weissberg, M.; Shaya, F.; Faigenboim-Doron, A.; Ung, K. L.; Pedersen, B. P.; Riov, J.; Klavins, E.; Dawid, C.; Hammes, U. Z.; Ben-Tal, N.; Napier, R.; Sadot, E.; Weinstain, R.
10.1101/2023.03.13.532257 — plant biology — Posted on 2023-12-04
4215 Stress granule dysfunction via chromophore-associated light inactivation
Koizumi, T.; Fujimoto, A.; Kawaguchi, H.; Kurosaki, T.; Kitamura, A.
10.1101/2023.08.12.553066 — biophysics — Posted on 2023-12-04
4216 Transwell-based microphysiological platform for high-resolution imaging of airway tissues
Kurmashev, A.; Boos, J. A.; Swart, L.; Laventie, B.-J.; Junne, T.; Suetterlin, R.; Jenal, U.; Hierlemann, A.
10.1101/2023.11.22.567838 — bioengineering — Posted on 2023-12-04
4218 Cooperative progression of colitis and leukemia modulated by clonal hematopoiesis via PTX3/IL-1β; pro-inflammatory signaling
He, H.; Wen, Y.; Yu, H.; Liu, J.; Huo, Q.; Jin, W.; Wang, Z.; Du, G.; Du, J.; Wang, H.; Zhao, Z.; Cai, Z.
10.1101/2023.08.29.555330 — immunology — Posted on 2023-12-04
4219 A New Highly Efficient Molecule for Both Optogenetic and Chemogenetic Control Driven by FRET Amplification of BioLuminescence
Bjorefeldt, A.; Murphy, J.; Crespo, E. L.; Lambert, G. G.; Prakash, M.; Ikefuama, E. C.; Friedman, N.; Brown, T. M.; Lipscombe, D.; Moore, C. I.; Hochgeschwender, U.; Shaner, N. C.
10.1101/2023.06.26.545546 — neuroscience — Posted on 2023-12-04
4220 LEAFY interacts with WHEAT ORTHOLOG OF APO1 to regulate spikelet number per spike in wheat
Paraiso, F.; Zhang, J.; Lin, H.; Li, C.; Woods, D. P.; Lan, T.; Burguener, G. F.; Debernardi, J. M.; Joe, A.; Dubcovsky, J.
10.1101/2023.11.02.565263 — plant biology — Posted on 2023-12-04
4222 A foundational atlas of autism protein interactions reveals molecular convergence
Wang, B.; Vartak, R.; Zaltsman, Y.; Naing, Z. Z. C.; Hennick, K. M.; Polacco, B. J.; Bashir, A.; Eckhardt, M.; Bouhaddou, M.; Xu, J.; Sun, N.; Lasser, M.; Zhou, Y.; Guiley, K. Z.; Chan, U.; Kaye, J. A.; Khare, P.; Drake, S.; Drury, V.; Burke, D. F.; Gonzalez, S.; Alkhairy, S.; Morris, M.; Baum, T.; Krasnoff, R.; Wang, S.; Pham, P.; Arbalaez, J.; Pratt, D.; Chag, S.; Rolland, T.; Bourgeron, T.; Finkbeiner, S.; Bandyopadhay, S.; Ideker, T.; Beltrao, P.; Willsey, H. R.; Obernier, K.; Nowakowski, T. J.; Huttenhain, R.; State, M. W.; Willsey, A. J.; Krogan, N. J.
10.1101/2023.12.03.569805 — systems biology — Posted on 2023-12-03
4223 An optimised protocol for quality control of gene therapy vectors using Nanopore direct RNA sequencing
Zeglinski, K.; Montellese, C.; Ritchie, M. E.; Alhamdoosh, M.; Vonarburg, C.; Bowden, R.; Jordi, M.; Gouil, Q.; Aeschimann, F.; Hsu, A.
10.1101/2023.12.03.569756 — genomics — Posted on 2023-12-03
4225 Structural basis of anticancer drug recognition and amino acid transport by LAT1
Lee, Y.; Jin, C.; Ohgaki, R.; Xu, M.; Ogasawara, S.; Warshamanage, R.; Yamashita, K.; Murshudov, G.; Nureki, O.; Murata, T.; Kanai, Y.
10.1101/2023.12.03.567112 — biochemistry — Posted on 2023-12-03
4228 High yield, low magnesium flexizyme reactions in a water-ice eutectic phase
Davisson, J.; Alejo, J.; Blank, M.; Kalb, E.; Prasad, A.; Knudson, I.; Schepartz, A.; Engelhart, A. E.; Adamala, K. P.
10.1101/2023.12.03.569792 — synthetic biology — Posted on 2023-12-03
4229 RenSeq of Silphium integrifolium Reveals a Biotic Gradient for Disease Resistance
Keepers, K. G.; Peterson, K.; Raduski, A. R.; Turner, K. M.; van Tassel, D.; Smith, K. P.; Harkess, A.; Bever, J. D.; Brandvain, Y.
10.1101/2023.05.02.539110 — evolutionary biology — Posted on 2023-12-03
4230 Long-insert sequence capture detects high copy numbers in a defence-related beta-glucosidase gene Betaglu-1 with large variations in white spruce but not Norway spruce
Hung, T. H.; Wu, E. T. Y.; Zeltins, P.; Jansons, A.; Ullah, A.; Erbilgin, N.; Bohlmann, J.; Bousquet, J.; Birol, I.; Clegg, S.; MacKay, J.
10.1101/2023.08.18.551884 — evolutionary biology — Posted on 2023-12-03
4231 Bacterial multispecies invasion of human epithelial bladder cells
Abell-King, C.; Pokhrel, A.; Rice, S.; Duggin, I. G.; Söderström, B.
10.1101/2023.02.16.528894 — microbiology — Posted on 2023-12-03
4232 Gut microbiota profile in CDKL5 deficiency disorder patients as a potential marker of clinical severity
Borghi, E.; Xynomilakis, O.; Ottaviano, E.; Ceccarani, C.; Vigano', I.; Tognini, P.; Vignoli, A.
10.1101/2023.12.01.569361 — microbiology — Posted on 2023-12-03
4236 Ivermectin increases striatal cholinergic activity to facilitate dopamine terminal function
Wadsworth, H. A.; Warnecke, A.; Barlow, J. C.; Robinson, J. K.; Steimle, E.; Ronstroem, J. W.; Williams, P. E.; Galbraith, C. J.; Baldridge, J.; Jakowec, M. W.; Davies, D. L.; Yorgason, J. T.
10.1101/2023.11.30.569432 — neuroscience — Posted on 2023-12-03
4237 Negative feedback control of hunger circuits by the taste of food
Aitken, T. J.; Ly, T.; Shehata, S.; Sivakumar, N.; La Santa Medina, N.; Gray, L. A.; Dundar, N.; Barnes, C.; Knight, Z. A.
10.1101/2023.11.30.569492 — neuroscience — Posted on 2023-12-03
4239 Developmental remodeling repurposes larval neurons for sexual behaviors in adult Drosophila
Diamandi, J. A.; Duckhorn, J. C.; Miller, K. E.; Weinstock, M.; Leone, S.; Murphy, M. R.; Shirangi, T. R.
10.1101/2023.11.30.569472 — neuroscience — Posted on 2023-12-03
4241 Cholinergic modulation of rearing in rats performing a spatial memory task
Cassity, S. T.; Choi, I. J.; Gregory, B. H.; Igbasanmi, A. M.; Bickford, S. C.; Moore, K. T.; Seraiah, A. E.; Layfield, D.; Newman, E. L.
10.1101/2023.10.14.559618 — neuroscience — Posted on 2023-12-03
4242 Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments
Lang, S.; Fletcher, D. A.; Petit, A.-P.; Luise, N.; Fyfe, P. K.; Zuccotto, F.; Porter, D.; Hope, A.; Bellany, F.; Kerr, C.; MacKenzie, C. J.; Wyatt, P. G.; Gray, D. W.
10.1101/2023.12.01.569544 — pharmacology and toxicology — Posted on 2023-12-03
4248 Kinetics-based Inference of Environment-Dependent Microbial Interactions and Their Dynamic Variation
Song, H.-S.; Lee, N.-R.; Kessell, A. K.; McCullough, H. C.; Park, S.-Y.; Zhou, K.; Lee, D.-Y.
10.1101/2022.08.27.505268 — bioinformatics — Posted on 2023-12-03
4252 Length-weight relationships of the French pikes Esox spp (Teleostei, Esocidae)
Royer, L.; Teletchea, F.; Delavergne, S.; Lafitte, F.; Escarpit, M.; Molina, Q.; Breugnot, E.; Cosson, E.; L Hostis, A.; Denys, G. P.
10.1101/2023.12.01.569518 — ecology — Posted on 2023-12-03
4253 Membrane contact sites regulate vacuolar fission via sphingolipid metabolism
Hanaoka, K.; Nishikawa, K.; Ikeda, A.; Schlarmann, P.; Yamashita, S.; Nakaji, A.; Fujii, S.; Funato, K.
10.1101/2023.06.21.546015 — cell biology — Posted on 2023-12-03
4254 Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
Tan, B.; Zhang, X.; Ansari, A.; Jadhav, P.; Tan, H.; Li, K.; Chopra, A.; Ford, A.; Chi, X.; Figueras, F. R.; Arnold, E.; Deng, X.; Wang, J.
10.1101/2023.12.01.569653 — microbiology — Posted on 2023-12-03
4255 Novel isolates expand the physiological diversity of Prochlorococcus and illuminate its macroevolution
Becker, J. W.; Pollak, S.; Berta-Thompson, J. W.; Becker, K. W.; Braakman, R.; Dooley, K. D.; Hackl, T.; Coe, A.; Arellano, A.; LeGault, K. N.; Berube, P. M.; Biller, S. J.; Cubillos-Ruiz, A.; Van Mooy, B. A. S.; Chisholm, S. W.
10.1101/2023.12.03.569780 — microbiology — Posted on 2023-12-03
4257 Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts
Francois, A. K.; Rohani, A.; Loftus, M. S.; Dochnal, S. A.; Hrit, J.; McFarlane, S.; Whitford, A. L.; Lewis, A.; Krakowiak, P. A.; Boutell, C.; Rothbart, S. B.; Kashatus, D.; Cliffe, A. R.
10.1101/2023.12.03.569766 — microbiology — Posted on 2023-12-03
4258 Spatial and Temporal Resolution of Cyanobacterial Bloom Chemistry Reveals an Open-Ocean Trichodesmium thiebautii as a Talented Producer of Specialized Metabolites
Via, C. W.; Grauso, L.; McManus, K. M.; Kirk, R. D.; Kim, A. M.; Webb, E. A.; Held, N. A.; Saito, M.; Scarpato, S.; Zimba, P. V.; Moeller, P. D.; Mangoni, A.; Bertin, M. J.
10.1101/2023.12.03.569781 — microbiology — Posted on 2023-12-03
4259 Structural Host-Virus Interactome Profiling of Intact Infected Cells
Bogdanow, B.; Mühlberg, L.; Gruska, I.; Vetter, B.; Ruta, J.; Elofsson, A.; Wiebusch, L.; Liu, F.
10.1101/2023.12.03.569778 — microbiology — Posted on 2023-12-03
4260 Memory B cells dominate the early antibody-secreting cell response to SARS-CoV-2 mRNA vaccination in naive individuals independently of their antibody affinity
Li, Z.; Obraztsova, A.; Shang, F.; Oludada, O. E.; Malapit, J.; Busch, K.; van Straaten, M.; Stebbins, E.; Murugan, R.; Wardemann, H.
10.1101/2023.12.01.569639 — immunology — Posted on 2023-12-03
4263 Alterations of adult prefrontal circuits induced by early postnatal fluoxetine treatment mediated by 5-HT7 receptors.
De Stasi, A. M.; de San Martin, J. Z.; Soto, N. N.; Aguirre, A.; Olusakin, J.; Lourenco, J.; Gaspar, P.; Bacci, A.
10.1101/2023.11.30.569458 — neuroscience — Posted on 2023-12-03
4266 Glutaredoxin regulation of primary root growth is associated with early drought stress tolerance in pearl millet
de la Fuente Canto, C.; Grondin, A.; Sine, B.; Debieu, M.; Belin, C.; Hajjarpoor, A.; Atkinson, J.; Passot, S.; Salson, M.; Orjuela, J.; Tranchant, C.; Brossier, J.-R.; Steffen, M.; Morgado, C.; Dinh, H. N.; Pandey, B. K.; Darmau, J.; Champion, A.; Petitot, A.-S.; Barrachina, C.; Pratlong, M.; Mounier, T.; Nakombo-Gbassault, P.; Gantet, P.; Gangashetty, P.; Guedon, Y.; Vadez, V.; Reichheld, J.-P.; Bennett, M. J.; Kane, N. A.; Guyomarc'h, S.; Wells, D. M.; Vigouroux, Y.; Laplaze, L.
10.1101/2023.02.02.526762 — plant biology — Posted on 2023-12-03
4268 Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion
Cole, A. R.; Buj, R.; Taher Elhaw, A.; Uboveja, A.; Tangudu, N. K.; Oesterreich, S.; Stallaert, W.; Hempel, N.; Aird, K. M.
10.1101/2023.12.02.569652 — cancer biology — Posted on 2023-12-03
4269 The balance between ATR and DDK activities controls TopBP1-mediated locking of dormant origins at the pre-IC stage
Koundrioukoff, S.; Kim, S.-J.; Alary, N.; Toffano, A.; Melendez-Garcia, R.; Wu, X.; Liu, Y.; Gnan, S.; El-Hilali, S.; Brison, O.; Rosselli, F.; Chen, C.-L.; Debatisse, M.
10.1101/2023.11.29.569233 — genetics — Posted on 2023-12-03
4270 Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence
Sha, K.; Zhang, R.; Maolake, A.; Singh, S.; Chatta, G.; Eng, K. H.; Nastiuk, K. L.; Krolewski, J. J.
10.1101/2023.12.01.569685 — cancer biology — Posted on 2023-12-03
4272 The Lateral Ganglionic Eminence Does Not Generate Cortical Oligodendrocytes
Li, J.; Yang, F.; Tian, Y.; Wang, Z.; Qi, D.; Yang, Z.; Song, J.; Ding, J.; Wang, X.; Zhang, z.
10.1101/2023.12.01.569674 — developmental biology — Posted on 2023-12-03
4273 CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy
Zaninello, M.; Schlegel, T.; Nolte, H.; Rehman, P. M. U.; Savino, E.; Barth, E.; Wuestenberg, H.; Uddin, T.; Wolff, L.; Wirth, B.; Lehmann, H.; Cioni, J.-M.; Langer, T.; Rugarli, E.
10.1101/2023.12.02.569712 — cell biology — Posted on 2023-12-03
4275 Demonstration of Bioplastic Production from CO2 and Formate using the Reductive Glycine Pathway in E. coli
Fedorova, D.; Ben-Nissan, R.; Milshtein, E.; Jona, G.; Dezorella, N.; Feiguelman, G.; Fedorov, R.; Gomaa, A.; Lindner, A. B.; Noor, E.; Milo, R.
10.1101/2023.12.02.569694 — synthetic biology — Posted on 2023-12-03
4276 TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma
Gallo-Oller, G. O.; Pons, G.; Sansa-Girona, J.; Navarro, N.; Zarzosa, P.; Garcia-Gilabert, L.; Cabre Fernandez, P.; Guillen Barrieza, G.; Valero-Arrese, L.; Segura, M. F.; Lizcano, J. M.; Sanchez de Toledo, J.; Moreno, L.; Gallego, S.; Roma, J.
10.1101/2023.12.01.569530 — cancer biology — Posted on 2023-12-03
4277 Mitochondrial Apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
Lubeck, M.; Naha, R.; Schaumkessel, Y.; Westhoff, P.; Stefanski, A.; Petzsch, P.; Stuehler, K.; Koehrer, K.; Weber, A. P. M.; Anand, R.; Reichert, A. S.; Kondadi, A. K.
10.1101/2023.12.01.569567 — cell biology — Posted on 2023-12-03
4283 Comparative analysis of methodologies for detecting extrachromosomal circular DNA
Gao, X.; Liu, K.; Luo, S.; Tang, M.; Liu, N.; Jiang, C.; Fang, J.; Li, S.; Hou, Y.; Guo, C.; Qu, K.
10.1101/2023.12.01.569546 — cancer biology — Posted on 2023-12-03
4284 The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells
Piscopo, V. E. C.; Chapleau, A.; Blaszczyk, G. J.; Sirois, J.; You, Z.; Soubannier, V.; Bernard, G.; Antel, J. P.; Durcan, T.
10.1101/2023.12.01.569591 — cell biology — Posted on 2023-12-03
4286 Distributed representations of prediction error signals across the cortical hierarchy are synergistic
Gelens, F.; Aijala, J.; Roberts, L.; Komatsu, M.; Uran, C.; Jensen, M. A.; Miller, K. J.; Ince, R. A. A.; Garagnani, M.; Vinck, M.; Canales-Johnson, A.
10.1101/2023.01.12.523735 — neuroscience — Posted on 2023-12-03
4288 Specific cPRC1 complexes are co-opted to mediate oncogenic gene repression in diffuse midline glioma
Gannon, D.; Lagan, E.; Silva, A. J.; Bibawi, P.; Doherty, A.; Nimmo, D.; McCole, R.; Monger, C.; Genesi, G.; Vanderlinden Dibekeme, A.; Innes, J.; Yang, L.; Chen, B.; van Mierlo, G.; Jansen, P. W.; Wynne, K.; Sanchez Rivera, F. J.; Soto-Feliciano, Y.; Vermeulen, M.; Oliviero, G.; Chen, C. W.; Phillips, R.; Bracken, A. P.; Brien, G.
10.1101/2023.12.02.569451 — cancer biology — Posted on 2023-12-03
4289 LSD1/KDM1A is essential for neural stem cell differentiation in mice
Falkenberry, E. C.; Reeves, M.; Scott, A. M.; Myrick, D. A.; Fallini, C.; Bassell, G. J.; Katz, D. J.
10.1101/2023.12.02.569711 — genetics — Posted on 2023-12-03
4290 Depletion-assisted multiplexed cell-free RNA sequencing reveals distinct human and microbial signatures in plasma versus extracellular vesicles
Wang, H.; Zhan, Q.; Ning, M.; Guo, H.; Wang, Q.; Zhao, J.; Bao, P.; Xing, S.; Chen, S.; Zuo, S.; Li, M.; Wang, P.; Lu, Z. J.
10.1101/2023.01.31.526408 — molecular biology — Posted on 2023-12-03
4291 Early Pastoralism in Central European Forests: Insights from Ancient Environmental Genomics
Zampirolo, G.; Holman, L. E.; Sawafuji, R.; Ptakova, M.; Kovacikova, L.; Sida, P.; Pokorny, P.; Pedersen, M. W.; Walls, M.
10.1101/2023.12.01.569562 — genomics — Posted on 2023-12-03
4292 A female-biased gene expression signature of dominance in cooperatively breeding meerkats
Campbell, C. R.; Manser, M.; Shiratori, M.; Williams, K.; Barreiro, L.; Clutton-Brock, T. H.; Tung, J.
10.1101/2023.12.01.569325 — animal behavior and cognition — Posted on 2023-12-03
4294 Adipokinetic hormone signaling mediates the fecundity of Diaphorina citri infected by Candidatus Liberibacter asiaticus
Li, J.; Holford, P.; Beattie, G. A. C.; Wu, S.; He, J.; Tan, S.; Wang, D.; He, Y.; Cen, Y.; Nian, X.
10.1101/2023.10.24.563719 — ecology — Posted on 2023-12-03
4295 Role of Immature Choroid Plexus in the Pathology of Autism Spectrum Disorder
Tanabe, M.; Saito, Y.; Takasaki, A.; Nakano, K.; Suzuki, C.; Kawamura, N.; Hattori, A.; Nagashima, S.; Oikawa, M.; Yanagi, S.; Yamaguchi, T.; Fukuda, T.
10.1101/2023.12.01.569662 — neuroscience — Posted on 2023-12-03
4298 Adaptive stretching of representations across brain regions and deep learning model layers
Zhang, X.-Y.; Bobadilla-Suarez, S.; Luo, X.; Lemonari, M.; Brincat, S. L.; Siegel, M.; Miller, E. K.; Love, B. C.
10.1101/2023.12.01.569615 — neuroscience — Posted on 2023-12-03
4300 On Global Brain Reconfiguration after Local Manipulations
Rabuffo, G.; Lokossou, H.-A.; Li, Z.; Ziaee-Mehr, A.; Hashemi, M.; Quilichini, P. P.; Ghestem, A.; Arab, O.; Esclapez, M.; Verma, P.; Raj, A.; Gozzi, A.; Sorrentino, P.; Chuang, K.-H.; Perles-Barbacaru, T.-A.; Viola, A.; Jirsa, V. K.; Bernard, C.
10.1101/2023.09.08.556815 — neuroscience — Posted on 2023-12-03
4301 The Structural Role of N170 in Substrate-assisted Deacylation in KPC-2 β-Lactamase
Parwana, D.; Gu, J.; Chen, S.; Bethel, C.; Marshall, E. K.; Hujer, A. M.; Bonomo, R. A.; Haider, S.
10.1101/2023.05.22.541848 — biophysics — Posted on 2023-12-02
4302 Prioritization of The Zinc finger domain within BCL11A gene by the Amelioration capability of hemoglobinopathies using CRISPR-Cas9 technology
Mumtaz, K.; Hussain, I.; Iftikhar, F.; Rehman, F. u.; Muhammad, J.; Farooq, S.; Hassan, H.; Fatima, A.; Ottmann, O. G.; Mian, A. A.
10.1101/2023.11.28.568974 — molecular biology — Posted on 2023-12-02
4303 Profound seizure suppression and disease modification by targeting JAK1, a key driver of a pro-epileptogenic gene network.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Espina, J. E. C.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-12-02
4308 Suppression of autoimmune arthritis and neuroinflammation via an amino acid-conjugatedbutyrate prodrug with enhanced oral bioavailability
Cao, S.; Budina, E.; Raczy, M. M.; Solanki, A.; Nguyen, M.; Beckman, T. N.; Reda, J. W.; Hultgren, K.; Ang, P.; Slezak, A. J.; Hesser, L. A.; Alpar, A. T.; Refvik, K. C.; Shores, L. S.; Pillai, I.; Wallace, R. P.; Dhar, A.; Watkins, E.; Hubbell, J. A.
10.1101/2023.04.28.538720 — bioengineering — Posted on 2023-12-02
4310 Histone marks enable formation of immiscible phase-separated chromatin compartments
Sun, W.; Wang, J.; Liu, W.; Tang, B.; Qu, H.; Wang, J.; Li, H.; Xie, W.; Li, P.
10.1101/2023.12.02.569699 — biochemistry — Posted on 2023-12-02
4311 Structural basis of the mechanism and inhibition of a human ceramide synthase
Pascoa, T. C.; Pike, A. C. W.; Tautermann, C. S.; Chi, G.; Traub, M.; Quigley, A.; Chalk, R.; Stefanic, S.; Thamm, S.; Pautsch, A.; Carpenter, E. P.; Schnapp, G.; Sauer, D. B.
10.1101/2023.12.02.569723 — biochemistry — Posted on 2023-12-02
4315 Small-molecule activators of a bacterial signaling pathway inhibit virulence
Mansour, K. E.; Qi, Y.; Yan, M.; Ramstrom, O.; Priebe, G. P.; Schaefers, M. M.
10.1101/2023.12.02.569726 — microbiology — Posted on 2023-12-02
4317 Streptococcus suis infection on European farms is associated with an altered tonsil microbiome and resistome
Fredriksen, S.; Neila-Ibanez, C.; Hennig-Pauka, I.; Guan, X.; Dunkelberger, J.; Fernandes de Oliveira, I.; Ferrando, M. L.; Correa-Fiz, F.; Aragon, V.; Boekhorst, J.; van Baarlen, P.; Wells, J. M.
10.1101/2022.08.01.500980 — microbiology — Posted on 2023-12-02
4319 Genomic plasticity is a blueprint of diversity in Salmonella lineages
Krishnakant Kushwaha, S.; Anand, A.; Wu, Y.; Leonardo Avila, H.; Sicheritz-Ponten, T.; Millard, A.; Amol Marathe, S.; Nobrega, F. L.
10.1101/2023.12.02.569618 — microbiology — Posted on 2023-12-02
4320 Convergent evolution of monocyte differentiation in adult skin permits repair of the Langerhans cell network
Appios, A.; Davies, J.; Sirvent, S.; Henderson, S.; Trzebanski, S.; Schroth, J.; Law, M. L.; Boal Carvalho, I.; Yuan-Hao Kan, H.; Major, C.; Vallejo, A.; Hall, N. J.; Ardern-Jones, M.; Henson, S. M.; Emmerson, E.; Jung, S.; Polak, M. E.; Bennett, C. L.
10.1101/2023.11.13.566862 — immunology — Posted on 2023-12-02
4321 A Burst-dependent Thalamocortical Substrate for Visual Rivalry
Whyte, C. J.; Munn, B. R.; Aru, J.; Larkum, M.; John, Y.; Muller, E. J.; Shine, J. M.
10.1101/2023.07.13.548934 — neuroscience — Posted on 2023-12-02
4324 LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton
Tombesi, G.; Kompella, S.; Favetta, G.; Chen, C.; Zhao, Y.; Sevegnani, M.; Marte, A.; Battisti, I.; Morosin, E.; Ornaghi, M.; Iannotta, L.; Plotegher, N.; Civiero, L.; Onofri, F.; Eickholt, B. J.; Piccoli, G.; Arrigoni, G.; Beccano-Kelly, D.; Manzoni, C.; Parisiadou, L.; Greggio, E.
10.1101/2022.10.31.514622 — neuroscience — Posted on 2023-12-02
4328 PROTEOME-SCALE RECOMBINANT STANDARDS AND A ROBUST HIGH-SPEED SEARCH ENGINE TO ADVANCE CROSS-LINKING MS-BASED INTERACTOMICS
Clasen, M. A.; Ruwolt, M.; Kurt, L. U.; Gozzo, F. C.; Wang, S.; Chen, T.; Carvalho, P. C.; Lima, D. B.; Liu, F.
10.1101/2023.11.30.569448 — bioinformatics — Posted on 2023-12-02
4332 Filter-aided expansion proteomics
Dong, Z.; Zhu, Y.; Zhang, F.; Wu, C.; Chen, T.; Chen, J.; Jiang, W.; Xiao, Q.; Zheng, S.; Piatkevich, K. D.; Guo, T.
10.1101/2023.11.29.569242 — biochemistry — Posted on 2023-12-02
4334 Mapping protein-DNA interactions with DiMeLo-seq
Maslan, A.; Altemose, N.; Mishra, R.; Marcus, J.; Brennan, L. D.; Sundararajan, K.; Karpen, G.; Straight, A. F.; Streets, A. M.
10.1101/2022.07.03.498618 — genomics — Posted on 2023-12-02
4337 Functional Connectivity Abnormalities of the Subgenual Anterior Cingulate Cortex: Implications for Transcranial Magnetic Stimulation in Depression
Chen, X.; Lu, B.; Wang, Y.-W.; Li, X.-Y.; Wang, Z.-H.; Li, H.-X.; Liao, Y.-F.; Blumberger, D. M.; Castellanos, F. X.; Cao, L.-P.; Chen, G.-M.; Chen, J.-S.; Chen, T.; Chen, T.-L.; Chen, Y.-R.; Cheng, Y.-Q.; Chu, Z.-S.; Cui, S.-X.; Cui, X.-L.; Deng, Z.-Y.; Gao, Q.-L.; Gong, Q.-Y.; Guo, W.-B.; He, C.-C.; Hu, Z.-J.-Y.; Huang, Q.; Ji, X.-L.; Jia, F.-N.; Kuang, L.; Li, B.-J.; Li, F.; Li, T.; Li, X.; Lian, T.; Liu, X.-Y.; Liu, Y.-S.; Liu, Z.-N.; Long, Y.-C.; Lu, J.-P.; Qiu, J.; Shan, X.-X.; Si, T.-M.; Sun, P.-F.; Wang, C.-Y.; Wang, H.-L.; Wang, H.-N.; Wang, X.; Wang, Y.; Wu, C.-N.; Wu, X.-P.; Wu, X.-
10.1101/2023.03.09.531726 — neuroscience — Posted on 2023-12-02
4338 Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization
Ge, R.; Yu, Y.; Qi, Y. X.; Fan, Y. V.; Chen, S.; Gao, C.; Haas, S. S.; Modabbernia, A.; New, F.; Agartz, I.; Asherson, P.; Ayesa-Arriola, R.; Banaj, N.; Banaschewski, T.; Baumeister, S.; Bertolino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Buckner, R.; Buitelaar, J. K.; Cannon, D. M.; Caseras, X.; Cervenka, S.; Conrod, P. J.; Crespo-Facorro, B.; Crivello, F.; Crone, E. A.; de Haan, L.; de Zubicaray, G. I.; Di Giorgio, A.; Erk, S.; Fisher, S. E.; Franke, B.; Frodl, T.; Glahn, D. C.; Grotegerd, D.; Gruber, O.; Gruner, P.; Gur, R. E.; G
10.1101/2023.01.30.523509 — bioinformatics — Posted on 2023-12-02
4340 A red light-induced genetic system for control of extracellular electron transfer
Zhao, F.; Niman, C. M.; Ostovar, G.; Chavez, M. S.; Atkinson, J. T.; Bonis, B. M.; Gralnick, J. A.; El-Naggar, M. Y.; Boedicker, J. Q.
10.1101/2023.12.02.569691 — synthetic biology — Posted on 2023-12-02
4347 In situ lipidomics of Staphylococcus aureus osteomyelitis using imaging mass spectrometry
Good, C. J.; Butrico, C. E.; Colley, M. E.; Gibson-Corley, K. N.; Cassat, J. E.; Spraggins, J. M.; Caprioli, R. M.
10.1101/2023.12.01.569690 — biochemistry — Posted on 2023-12-02
4349 CTCF-mediated 3D chromatin predetermines the gene expression program in the male germline
Kitamura, Y.; Takahashi, K.; Maezawa, S.; Munakata, Y.; Sakashita, A.; Kaplan, N.; Namekawa, S. H.
10.1101/2023.11.30.569508 — developmental biology — Posted on 2023-12-02
4350 Human naive stem cell models reveal the role of FGF signalling in hypoblast specification in the human embryo
Dattani, A.; Simon, E. C.; Radley, A.; Heydari, T.; Taheriabkenar, Y.; Carlisle, F.; Lin, S.; Mill, J.; Zandstra, P. W.; Nichols, J.; Guo, G.
10.1101/2023.11.30.569161 — developmental biology — Posted on 2023-12-02
4351 Antigenic and genetic diversity of H1 and H3 influenza A viruses in swine in Brazil
Lopes, S.; Anderson, T. K.; Schaefer, R.; Tochetto, C.; Gava, D.; Cantao, M. E.; Ciacci-Zanella, J. R.; Vincent Baker, A. L.; Lewis, N. S.
10.1101/2023.12.01.569635 — microbiology — Posted on 2023-12-02
4352 Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography.
Watanabe, R.; Zyla, D.; Parekh, D.; Hong, C.; Jones, Y.; Schendel, S. L.; Wan, W.; Castillon, G.; Saphire, E. O.
10.1101/2023.12.01.569666 — microbiology — Posted on 2023-12-02
4354 Complex sporulation-specific expression of transcription termination factor Rho highlights its involvement in Bacillus subtilis cell differentiation
Bidnenko, V.; Chastanet, A.; Pechoux, C.; Redko-Hamel, Y.; Pellegrini, O.; Durand, S.; Condon, C.; Jules, M.; Bidnenko, E.
10.1101/2023.12.01.569620 — microbiology — Posted on 2023-12-02
4355 Multi-omics framework to reveal the molecular determinants of fermentation performance in wine yeast populations
de Celis, M.; Ruiz, J.; Benitez-Dominguez, B.; Vicente, J.; Tomasi, S.; Izquierdo-Gea, S.; Rozes, N.; Ruiz-de-Vila, C.; Gombau, J.; Zamora, F.; Barroso, A.; Terron-Camero, L. C.; Andres-Leon, E.; Santos, A.; Belda, I.
10.1101/2023.12.02.569693 — microbiology — Posted on 2023-12-02
4359 Multi-Modal Mass Spectrometry Identifies a Conserved Protective Epitope in S. pyogenes Streptolysin O
Tang, D.; Gueto-Tettay, C. A.; Hjortswang, E.; Ströbaek, J.; Ekström, S.; Happonen, L.; Malmström, L.; Malmström, J.
10.1101/2023.12.02.569700 — biochemistry — Posted on 2023-12-02
4366 Diagnostic images for mild cognitive impairment reveal biomarker status and abnormal scene processing
Bai, Y.; Peters, O.; Freiesleben, S. D.; Fenski, F.; Priller, J.; Spruth, E. J.; Schneider, A.; Fliessbach, K.; Wiltfang, J.; Bartels, C.; Rostamzadeh, A.; Glanz, W.; Teipel, S.; Kilimann, I.; Laske, C.; Munk, M. H.; Spottke, A.; Roy-Kluth, N.; Brosseron, F.; Wagner, M.; Frommann, I.; Luesebrink, F.; Ramirez, A.; Dechent, P.; Hetzer, S.; Scheffler, K.; Yakupov, R.; Jessen, F.; Duezel, E.; Bainbridge, W. A.
10.1101/2023.11.30.569265 — neuroscience — Posted on 2023-12-02
4375 A point cloud segmentation framework for image-based spatial transcriptomics
Defard, T.; Laporte, H.; Mallick, A.; Soulier, J.; Curras-Alonso, S.; Weber, C.; Massip, F.; Londono-Vallejo, J.-A.; Fouillade, C.; Mueller, F.; Walter, T.
10.1101/2023.12.01.569528 — bioinformatics — Posted on 2023-12-02
4378 Molecular subtypes of high grade serous ovarian cancer across racial groups and gene expression platforms
Davidson, N. R.; Barnard, M. E.; Hippen, A. A.; Campbell, A.; Johnson, C.; Way, G. P.; Dalley, B. K.; Berchuck, A.; Salas, L. A.; Peres, L. C.; Marks, J. R.; Schildkraut, J. M.; Greene, C. S.; Doherty, J. A.
10.1101/2023.11.01.565179 — cancer biology — Posted on 2023-12-02
4379 Printing, Characterising, and Assessing Transparent 3D Printed Lenses for Optical Imaging
Rooney, L. M.; Christopher, J.; Watson, B.; Susir Kumar, Y.; Copeland, L.; Walker, L. D.; Foylan, S.; Amos, W. B.; Bauer, R.; McConnell, G.
10.1101/2023.11.22.568002 — biophysics — Posted on 2023-12-02
4380 Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors
Shepherdson, J. L.; Friedman, R. Z.; Zheng, Y.; Sun, C.; Oh, I. Y.; Granas, D. M.; Cohen, B. A.; Chen, S.; White, M. A.
10.1101/2023.05.27.542576 — genomics — Posted on 2023-12-02
4381 Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse
Muronova, J.; Kherraf, Z. E.; Giordani, E.; Lambert, E.; Eckert, S.; Cazin, C.; Amiri-Yekta, A.; Court, M.; Chevalier, G.; Martinez, G.; Neirijnck, Y.; Kühne, F.; Wehrli, L.; Klena, N.; De Macedo, L.; Escoffier, J.; Hamel, V.; Guichard, P.; Coutton, C.; Mustapha, S. F. B.; Kharouf, M.; Bouin, A.-P.; Zouari, R.; Thierry-Mieg, N.; Nef, S.; Geimer, S.; Loeuillet, C.; Ray, P. F.; Arnoult, C.
10.1101/2023.02.27.530236 — genetics — Posted on 2023-12-02
4384 HIV-1 binds dynein directly to hijack microtubule transport machinery
Badieyan, S.; Lichon, D.; Andreas, M. P.; Gillies, J. P.; Peng, W.; Shi, J.; DeSantis, M. E.; Aiken, C. R.; Böcking, T.; Giessen, T. W.; Campbell, E. M.; Cianfrocco, M. A.
10.1101/2023.08.29.555335 — microbiology — Posted on 2023-12-02
4386 High-throughput analysis of dendritic and axonal arbors reveals transcriptomic correlates of neuroanatomy
Gliko, O.; Mallory, M.; Dalley, R.; Gala, R.; Gornet, J.; Zeng, H.; Sorensen, S.; Sumbul, U.
10.1101/2022.03.07.482900 — neuroscience — Posted on 2023-12-02
4387 Identification of conserved gene expression programs activated in multiple modes of torpor across vertebrate clades.
Weir, K.; Vega, N.; Busa, V.; Sajdak, B.; Kallestad, L.; Merriman, D.; Palczewski, K.; Carroll, J.; Blackshaw, S.
10.1101/2023.11.29.569284 — physiology — Posted on 2023-12-02
4389 Ferroptosis Promotes Pulmonary Hypertension
Vogel, N. T.; Annis, J.; Prisco, S.; Laixto Mancripe, N.; Blake, M.; Brittain, E. L.; Prins, K.; Kazmirczak, F.
10.1101/2023.01.19.524721 — biochemistry — Posted on 2023-12-02
4390 Determinants of spring migration departure dates in a New World sparrow: weather variables reign supreme
Byrd, A. J.; Talbott, K. M.; Smiley, T. M.; Verrett, T. B.; Gross, M.; Hladik, M. L.; Ketterson, E. D.; Becker, D.
10.1101/2023.11.17.567563 — ecology — Posted on 2023-12-02
4392 Evolution of a small phage protein overcomes antiphage defense in Enterococcus faecalis
Johnson, C. N.; Bullen, N. P.; Andersen, S. E.; Arya, G.; Marotta, S. R.; Whitney, J. C.; Duerkop, B. A.
10.1101/2023.11.16.567456 — microbiology — Posted on 2023-12-02
4394 A frontal cortical network is critical for language planning during spoken interaction
Castellucci, G. A.; Kovach, C. K.; Tabasi, F.; Christianson, D.; Greenlee, J. D.; Long, M. A.
10.1101/2023.08.26.554639 — neuroscience — Posted on 2023-12-02
4396 Adaptation to ARF6-depletion in KRAS-driven PDAC is abolished by targeting TLR2
Ghose, R.; Das, S.; Urgel-Solas, J.; Pezzano, F.; Datta, D.; Ghose, U.; Ganez-Zapater, A.; Pardo-Lorente, N.; Espinar, L.; Garcia, L.; Cannata, C.; Ruprecht, V.; Janic, A.; Sdelci, S.
10.1101/2023.11.30.569405 — cancer biology — Posted on 2023-12-02
4397 PURA and GLUT1: Sweet partners for brain health
Colombo, R. B.; Maxit, C.; Martinelli, D.; Anderson, M.; Masone, D.; Mayorga, L.
10.1101/2023.12.01.569363 — cell biology — Posted on 2023-12-02
4398 Leptomeningeal Neural Organoid (LMNO) Fusions as Models to Study Meninges-Brain Signaling
Jones, H. E.; Robertson, G. L.; Romero-Morales, A. I.; O'Rourke, R.; Siegenthaler, J. A.; Gama, V.
10.1101/2023.12.01.569648 — cell biology — Posted on 2023-12-02
4400 Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C NMDA receptors
Pineau, L.; Buhler, E.; Tarhini, S.; Bauer, S.; Crepel, V.; Watrin, F.; Cardoso, C.; Represa, A.; Szepetowski, P.; Burnashev, N.
10.1101/2023.12.01.569539 — neuroscience — Posted on 2023-12-02
4401 In-depth characterization of HINT1 pathogenic variants
Amor Barris, S.; Lazar, T.; Peeters, K.; Wodak, S.; Jordanova, A.
10.1101/2023.12.01.569336 — neuroscience — Posted on 2023-12-02
4402 PIEZO2-dependent rapid pain system in humans and mice.
Bouchatta, O.; Brodzki, M.; Manouze, H.; Carballo, G. B.; Kindstrom, E.; de-Faria, F. M.; Yu, H.; Kao, A. R.; Thorell, O.; Liljencrantz, J.; Ng, K. K.; Frangos, E.; Ragnemalm, B.; Saade, D.; Bharucha-Goebel, D.; Szczot, I.; Moore, W.; Terejko, K.; Cole, J.; Bonnemann, C.; Luo, W.; Mahns, D. A.; Larsson, M.; Gerling, G. J.; Marshall, A. G.; Chesler, A. T.; Olausson, H.; Nagi, S. S.; Szczot, M.
10.1101/2023.12.01.569650 — neuroscience — Posted on 2023-12-02
4404 First detection of Anopheles stephensi in Ghana using molecular surveillance
Afrane, Y. A.; Abdulai, A.; Mohammed, A. R.; Akuamoah-Boateng, Y.; Owusu-Asenso, C. M.; Sraku, I. K.; Yanney, S. A.; Malm, K.; Lobo, N. F.
10.1101/2023.12.01.569589 — ecology — Posted on 2023-12-01
4408 Testing SIPA1L2 as a modifier of CMT1A using mouse models
Murray, G. C.; Hines, T. J.; Tadenev, A. L. D.; Xu, I.; Züchner, S.; Burgess, R. W.
10.1101/2023.11.30.569428 — genetics — Posted on 2023-12-01
4409 Somatic Mosaicism in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Reveals Widespread Degeneration from Focal Mutations
Zhou, Z.; Kim, J.; Huang, A. Y.; Nolan, M.; Park, J.; Doan, R.; Shin, T.; Miller, M. B.; Chhouk, B.; Morillo, K.; Yeh, R. C.; Kenny, C.; Neil, J. E.; Lee, C.-Z.; Ohkubo, T.; Ravits, J.; Ansorge, O.; Ostrow, L. W.; Lagier-Tourenne, C.; Lee, E. A.; Walsh, C. A.
10.1101/2023.11.30.569436 — genetics — Posted on 2023-12-01
4412 The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila CNS.
Sukumar, S. K.; Antonydhason, V.; Molander, L.; Sandakly, J.; Kleit, M.; Umapathy, G.; Mendoza-Garcia, P.; Masudi, T.; Schlosser, A.; Nassel, D. R.; Wegener, C.; Shirinian, M.; Palmer, R.
10.1101/2023.06.02.543395 — developmental biology — Posted on 2023-12-01
4415 Task-evoked pulse wave amplitude tracks cognitive load
Pavlov, Y. G.; Gashkova, A. S.; Kasanov, D.; Kosachenko, A. I.; Kotyusov, A. I.; Kotchoubey, B.
10.1101/2023.06.16.545290 — neuroscience — Posted on 2023-12-01
4416 Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival
Tzouanas, C. N.; Sherman, M. S.; Shay, J. E. S.; Rubin, A. J.; Mead, B. E.; Dao, T. T.; Butzlaff, T.; Mana, M. D.; Kolb, K. E.; Walesky, C.; Pepe-Mooney, B. J.; Smith, C. J.; Prakadan, S. M.; Ramseier, M. L.; Tong, E. Y.; Joung, J.; Chi, F.; McMahon-Skates, T.; Winston, C. L.; Jeong, W.-J.; Aney, K. J.; Chen, E.; Nissim, S.; Zhang, F.; Deshpande, V.; Lauer, G. M.; Yilmaz, O. H.; Goessling, W.; Shalek, A. K.
10.1101/2023.11.30.569407 — systems biology — Posted on 2023-12-01
4419 Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
Dolcemascolo, R.; Heras-Herandez, M.; Goiriz, L.; Montagud-Martinez, R.; Requena-Menendez, A.; Ruiz, R.; Perez-Rafols, A.; Higuera-Rodriguez, R. A.; Perez-Ropero, G.; Vranken, W. F.; Martelli, T.; Kaiser, W.; Buijs, J.; Rodrigo, G.
10.1101/2022.11.22.516435 — synthetic biology — Posted on 2023-12-01
4422 ERBB signalling contributes to immune evasion in KRAS-driven lung adenocarcinoma
Laing, S.; Kruspig, B.; Shaw, R.; Officer-Jones, L.; Edwards, S.; McKinven, D.; Hsieh, Y.-C.; Powley, I.; Brady, N.; Pennie, R.; Kwan, R.; Lima, A.; Myrta, S.; Periyasamy, M.; Dye, I. C.; Nixon, C.; Clark, G.; Junttila, M. R.; Maddalo, D.; Miller, C.; Ali, S.; Fuchter, M. J.; Nickles, D.; Kirschner, K.; Brown, R. B.; LeQuesne, J.; Strathdee, D.; Coffelt, S. B.; Roberts, E.; Murphy, D. J.
10.1101/2023.07.24.550274 — cancer biology — Posted on 2023-12-01
4423 Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction
Latini, S.; Venafra, V.; Massacci, G.; Bica, V.; Graziosi, S.; Pugliese, G. M.; Iannuccelli, M.; Frioni, F.; Minnella, G.; Marra, J. D.; Chiusolo, P.; Pepe, G.; Helmer-Citterich, M.; Mougiakakos, D.; Boettcher, M.; Fischer, T.; Perfetto, L.; Sacco, F.
10.1101/2023.06.22.546072 — cancer biology — Posted on 2023-12-01
4424 Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy
Kazansky, Y.; Cameron, D.; Mueller, H. S.; Demarest, P.; Zaffaroni, N.; Arrighetti, N.; Zuco, V.; Kuwahara, Y.; Somwar, R.; Ladanyi, M.; Qu, R.; De Stanchina, E.; Dela Cruz, F. S.; Kung, A. L.; Gounder, M.; Kentsis, A.
10.1101/2023.02.06.527192 — cancer biology — Posted on 2023-12-01
4432 Engineered Bacillus subtilis as oral probiotics to target circulating lactic acid
Yang, M.; Hutchinson, N.; Yin, J.; Guan, M.; Wang, Z.; Chen, P.; Yang, S.; Crane, J. D.; Zhang, K.; Li, J.
10.1101/2023.11.30.569300 — bioengineering — Posted on 2023-12-01
4437 Microglial adipose triglyceride lipase regulates neuroinflammatory and behavioural responses to LPS
Robb, J. L.; Machuca-Parra, A. I.; Boisjoly, F.; Coursan, A.; Manceau, R.; Majeur, D.; Rodaros, D.; Bouyakdan, K.; Greffard, K.; Bilodeau, J.-F.; Forest, A.; Daneault, C.; Ruiz, M.; Laurent, C.; Arbour, N.; Laye, S.; Fioramonti, X.; Madore-Delpech, C.; Fulton, S.; Alquier, T.
10.1101/2023.11.30.569441 — neuroscience — Posted on 2023-12-01
4438 Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases
Song, F.; Kovac, V.; Mohammadi, B.; Littau, L.; Scharfenberg, F.; Angles, A. M.; Vanni, I.; Shafiq, M.; Orge, L.; Galliciotti, G.; Djakkani, S.; Linsenmeier, L.; Cernilec, M.; Hartman, K.; Jung, S.; Tatzelt, J.; Neumann, J. E.; Damme, M.; Tschirner, S. K.; Lichtenthaler, S. F.; Schmitz, M.; Zerr, I.; Puig, B.; Tolosa, E.; Ferrer, I.; Magnus, T.; Rupnik, M. S.; Sepulveda-Falla, D.; Matschke, J.; Smid, L. M.; Bresjanac, M.; Andreoletti, O.; Krasemann, S.; Foliaki, S. T.; Nonno, R.; Becker-Pauly, C.; Monzo, C.; Crozet, C.; Haigh, C. L.; Glatzel, M.; Serbec, V. C.; Altmeppen, H. C.
10.1101/2023.11.30.569390 — neuroscience — Posted on 2023-12-01
4442 Mechanism of homology search expansion during recombinational DNA break repair
Dumont, A.; Mendiboure, N.; Savocco, J.; Anani, L.; Moreau, P.; Thierry, A.; Modolo, L.; Jost, D.; Piazza, A.
10.1101/2023.12.01.569403 — genetics — Posted on 2023-12-01
4444 Structure, interaction, and nervous connectivity of beta cell primary cilia
Müller, A.; Klena, N.; Pang, S.; Garcia, L. E. G.; Sulaymankhil, D.; Topcheva, O.; Seliskar, M.; Mziaut, H.; Schöniger, E.; Friedland, D.; Kipke, N.; Kretschmar, S.; Münster, C.; Weitz, J.; Distler, M.; Kurth, T.; Schmidt, D.; Hess, H. F.; Xu, C. S.; Pigino, G.; Solimena, M.
10.1101/2023.12.01.568979 — cell biology — Posted on 2023-12-01
4446 The exotic thymidine modification 5-hydroxymethyluridine in dinoflagellate Amphidinium carterae
LI, C.; LI, Y.; WANG, Y.; Meng, X.; SHI, X.; ZHANG, Y.; LIANG, N.; HUANG, H.; LI, Y.; ZHOU, H.; XU, J.; XU, W.; CHEN, H.
10.1101/2023.11.30.569493 — molecular biology — Posted on 2023-12-01
4448 A mitochondrial quality control mechanism reverses the phagosome maturation arrest caused by Mycobacterium tuberculosis
Verma, S.; Das, M.; Sharma, R. D.; Yadav, V.; Thakur, S.; Sharma, P.; Marzuki, M.; Foo, S.; Piperno, G. M.; Khan, M. Z.; Mathew, B.; Bajpai, M.; Maras, J. S.; Howland, S.; Sarkar, S.; Benvenuti, F.; Singh, A.; Nandicoori, V.; Singhal, A.; Kumar, D.
10.1101/2023.12.01.569475 — microbiology — Posted on 2023-12-01
4449 Seasonally increasing parasite load is associated with microbiome dysbiosis in wild bumblebees
Young, M. G.; Just, J.; Lee, Y. J.; McMahon, T.; Gonzalez, J.; Noh, S.; Angelini, D. R.
10.1101/2023.11.30.569473 — microbiology — Posted on 2023-12-01
4450 Differential development of antibiotic resistance and virulence between Acinetobacter species
Darby, E. M.; Moran, R. A.; Holden, E.; Morris, T.; Harrison, F.; Clough, B.; McInnes, R. S.; Schneider, L.; Frickel, E. M.; Webber, M. A.; Blair, J. M. A.
10.1101/2023.12.01.569554 — microbiology — Posted on 2023-12-01
4452 The implicit influence of pitch contours and emotional timbre on P300 components in an own-name oddball paradigm
Pruvost-Robieux, E.; Joucla, C.; Benghanem, S.; Guha, R.; Liuni, M.; Gavaret, M.; Aucouturier, J.-J.
10.1101/2023.11.30.569381 — neuroscience — Posted on 2023-12-01
4453 Cortical responses to looming sources are explained away by the auditory periphery
Benghanem, S.; Guha, R.; Pruvost-Robieux, E.; Levi-Strauss, J.; Joucla, C.; Cariou, A.; Gavaret, M.; Aucouturier, J.-J.
10.1101/2023.11.30.569391 — neuroscience — Posted on 2023-12-01
4454 Profiling Expression Strategies for a Type III Polyketide Synthase in a Lysate-Based, Cell-free System
Sword, T. T.; Dinglasan, J. L. N.; Abbas, G. S. K.; Barker, J. W.; Spradley, M. E.; Greene, E. R.; Gooden, D. S.; Emrich, S. J.; Gilchrist, M. A.; Doktycz, M. J.; Bailey, C. B.
10.1101/2023.11.30.569483 — synthetic biology — Posted on 2023-12-01
4455 Time-of-day effects of drugs revealed by high-throughput deep phenotyping
Ector, C.; Schmal, C.; Didier, J.; De Landtsheer, S.; Finger, A.-M.; Muller-Marquardt, F.; Schulte, J.; Sauter, T.; Keilholz, U.; Herzel, H.; Kramer, A.; Granada, A. E.
10.1101/2023.11.30.569380 — cancer biology — Posted on 2023-12-01
4456 GABA(A) receptor activation drives GABARAP-Nix mediated autophagy to radiation-sensitize primary and brain-metastatic lung adenocarcinoma tumors
Bhatacharya, D.; Barille, R.; Toukam, D. K.; Gawali, V. S.; Kallay, L.; Ahmed, T.; Brown, H.; Rezvanian, S.; Karve, A.; Desai, P. B.; Medvedovic, M.; Wang, K.; Ionascu, D.; Harun, N.; Wang, C.; Baschnagel, A. M.; Kritzer, J. A.; Cook, J. M.; Krummel, D. P.; Sengupta, S.
10.1101/2023.11.29.569295 — cancer biology — Posted on 2023-12-01
4458 Bidirectional Energy Flow in the Photosystem II Supercomplex
Leonardo, C.; Yang, S.-J.; Orcutt, K.; Iwai, M.; Arsenault, E. A.; Fleming, G. R.
10.1101/2023.11.30.569278 — biophysics — Posted on 2023-12-01
4460 CIA: a Cluster Independent Annotation method to investigate cell identities in scRNA-seq data
Ferrari, I.; Battistella, M.; Vincenti, F.; Gobbini, A.; Notarbartolo, S.; Costanza, J.; Biffo, S.; Grifantini, R. M.; Abrignani, S.; Galeota, E.
10.1101/2023.11.30.569382 — bioinformatics — Posted on 2023-12-01
4463 Multi-task machine learning reveals the neuroanatomy fingerprint of mental processing
Wang, Z.; Chen, Y.; Mao, W.; Xiao, Z.; Cao, G.; Toussaint, P.-J.; Guo, W.; Zhao, B.; Sun, H.; Zhang, T.; Evans, A. C.; Jiang, X.
10.1101/2023.11.30.569385 — bioinformatics — Posted on 2023-12-01
4465 Elucidating the Glycan-Binding Specificity and Structure of Cucumis melo Agglutinin, a New R-Type Lectin
Lundstrom, J.; Gillon, E.; Chazalet, V.; Kerekes, N.; Di Maio, A.; Liu, Y.; Feizi, T.; Varrot, A.; Bojar, D.
10.1101/2023.11.30.569503 — biochemistry — Posted on 2023-12-01
4471 Do nocturnal pollinators carry a more conspecific pollen load than diurnal ones?
Razanajatovo, M.; Schurr, F. M.; Muhthassim, N.; Troesch, S.; Knop, E.
10.1101/2023.11.30.569345 — ecology — Posted on 2023-12-01
4476 Internally-consistent and fully-unbiased multimodal MRI brain template construction from UK Biobank: Oxford-MM
Arthofer, C.; Smith, S. M.; Douaud, G.; Bartsch, A.; Alfaro-Almagro, F.; Andersson, J. L. R.; Lange, F. J.
10.1101/2023.11.30.569378 — neuroscience — Posted on 2023-12-01
4479 Understanding and exploitation of host stress responses to protein production using novel transcriptomic analytics
Rode, C.; Beulig, F.; Jonsson, M.; Jahn, L.; Noerholm, M. H. H.; Palsson, B. O.; Ozdemir, E.; Yang, L.
10.1101/2023.11.30.569415 — systems biology — Posted on 2023-12-01
4482 Protected areas enhance avian food webs
Thompson, L. R.; Galiana, N.; Wells, K.; Lurgi, M.
10.1101/2023.11.30.569404 — ecology — Posted on 2023-12-01
4483 Thalamic network controllability changes and cognitive impairment in multiple sclerosis
Yang, Y.; Woollams, A.; Lipp, I.; Zhuo, Z.; Tomassini, V.; Liu, Y.; Trujillo-Barreto, N.; Muhlert, N.
10.1101/2023.11.29.568586 — neuroscience — Posted on 2023-12-01
4485 A (Sub)field Guide to Quality Control in Hippocampal Subfield Segmentation on High-resolution T2-weighted MRI
Canada, K. L.; Mazloum-Farzaghi, N.; Radman, G.; Adams, J. N.; Bakker, A.; Baumeister, H.; Berron, D.; Bocchetta, M.; Carr, V.; Dalton, M. A.; de Flores, R.; Keresztes, A.; LaJoie, R.; Mueller, S.; Raz, N.; Santini, T.; Shaw, T.; Stark, C. E. L.; Tran, T. T.; Wang, L.; Wisse, L.; Wuestefeld, A.; Yushkevich, P. A.; Olsen, R.; Daugherty, A.
10.1101/2023.11.29.568895 — neuroscience — Posted on 2023-12-01
4486 A Graph Matching Approach to Tracking Neurons in Freely-Moving C. elegans
Jones, C.; Barzegar-Keshteli, M.; Gross, A.; Obozinski, G.; Rahi, S. J.
10.1101/2023.11.30.569341 — neuroscience — Posted on 2023-12-01
4487 Maternofetal transfer of human NMDAR antibodies leads to cortical network defect in the adult
Altahini, S.; Doering, J.; Kuchling, J.; Backhaus, H.; Kreye, J.; Guimaraes-Backhaus, R.; Finke, C.; Pruess, H.; Stroh, A.
10.1101/2023.11.30.569370 — neuroscience — Posted on 2023-12-01
4489 TRAIL pathway suppression of cancer cell growth and immune cell-mediated tumor cell-killing in a senescent fibroblast-constructed tumor microenvironment
Zhang, S.; Huntington, K. E.; Zhou, L.; Seyhan, A. A.; Kun, B.; Carneiro, B. A.; Kreiling, J.; Sedivy, J. M.; El-Deiry, W. S.
10.1101/2023.11.30.569479 — cancer biology — Posted on 2023-12-01
4490 Diploid genome assembly of the Malbec grapevine cultivar enables haplotype-aware analysis of transcriptomic differences underlying clonal phenotypic variation
Calderon, L.; Carbonell-Bejerano, P.; Munoz, C.; Bree, L.; Sola, C.; Bergamin, D.; Tulle, W.; Gomez-Talquenca, S.; Lanz, C.; Royo, C.; Ibanez, J.; Martinez-Zapater, J. M.; Weigel, D.; Lijavetzky, D.
10.1101/2023.11.30.569420 — genomics — Posted on 2023-12-01
4492 Hepatic Vagal Afferents Convey Clock-Dependent Signals to Regulate Circadian Food Intake
Woodie, L. N.; Melink, L. C.; Midha, M.; de Araujo, A.; Geisler, C. E.; Alberto, A. J.; Krusen, B. M.; Zundell, D. M.; de Lartigue, G.; Hayes, M. R.; Lazar, M. A.
10.1101/2023.11.30.568080 — physiology — Posted on 2023-12-01
4493 The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
Riley, A. K.; Grant, M.; Snell, A.; Vichas, A.; Moorthi, S.; Urisman, A.; Castel, P.; Wan, L.; Berger, A.
10.1101/2023.11.30.569313 — cancer biology — Posted on 2023-12-01
4494 High-throughput ML-guided design of diverse single-domain antibodies against SARS-CoV-2
Angermueller, C.; Marie, Z.; Jester, B.; Engelhart, E.; Emerson, R.; Alipanahi, B.; McCaw, Z. R.; Roberts, J.; Lopez, R. M.; Younger, D.; Colwell, L.
10.1101/2023.12.01.569227 — bioinformatics — Posted on 2023-12-01
4495 CLIPPER 2.0: Peptide level annotation and data analysis for positional proteomics
Kalogeropoulos, K.; Haack, A. M.; Madzharova, E.; Di Lorenzo, A.; Hanna, R.; Schoof, E. M.; auf dem Keller, U.
10.1101/2023.11.30.569335 — bioinformatics — Posted on 2023-12-01
4496 Offline RL for generative design of protein binders
Tarasov, D.; Mbou Sob, U. A.; Arbesu, M.; Siboni, N.; Boyer, S.; Skwark, M.; Smit, A.; Bent, O.; Pretorius, A.
10.1101/2023.11.29.569328 — bioinformatics — Posted on 2023-12-01
4497 HPClas: A data-driven approach for identifying halophilic proteins based on catBoost
Shantong, H.; Zhikang, W.; Xiaoyu, W.; Menghan, J.; Shihui, W.; Guimin, Z.; Jiangning, S.
10.1101/2023.11.30.569348 — bioinformatics — Posted on 2023-12-01
4499 Graph-KIR: Graph-based KIR Copy Number Estimation and Allele Calling Using Short-read Sequencing Data
Lin, H.-Y.; Chuang, H.-W.; Hung, T.-K.; Wang, T.-J.; Lin, C.-J.; Hsu, J. S.; Hsu, C.-L.; Yang, Y.-C.; Chen, P.-L.; Chen, C.-Y.
10.1101/2023.11.29.568665 — bioinformatics — Posted on 2023-12-01
4500 FAIR Header Reference genome: A TRUSTworthy standard
Wright, A.; Wilkinson, M. D.; Mungall, C.; Cain, S.; Richards, S.; Sternberg, P.; Provin, E.; Jacobs, J. L.; Geib, S.; Raciti, D.; Yook, K.; Stein, L.; Molik, D. C.
10.1101/2023.11.29.569306 — bioinformatics — Posted on 2023-12-01
4504 The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes
Makova, K. D.; Pickett, B. D.; Harris, R. S.; Hartley, G. A.; Cechova, M.; Pal, K.; Nurk, S.; Yoo, D.; Li, Q.; Hebbar, P.; McGrath, B. C.; Antonacci, F.; Aubel, M.; Biddanda, A.; Borchers, M.; Bornberg, E.; Bouffard, G. G.; Brooks, S. Y.; Carbone, L.; Carrel, L.; Carroll, A.; Chang, P.-C.; Chin, C.-S.; Cook, D. E.; Craig, S. J. C.; de Gennaro, L.; Diekhans, M.; Dutra, A.; Garcia, G. H.; Grady, P. G. S.; Green, R. E.; Haddad, D.; Hallast, P.; Harvey, W. T.; Hickey, G.; Hillis, D. A.; Hoyt, S. J.; Jeong, H.; Kamali, K.; Pond, S. L. K.; LaPolice, T. M.; Lee, C.; Lewis, A. P.; Loh, Y.-H. E.; Maste
10.1101/2023.11.30.569198 — genomics — Posted on 2023-12-01
4505 Development of a sequence-based in silico OspA typing method for Borrelia burgdorferi sensu lato
Lee, J. T.; Li, Z.; Nunez, L. D.; Katzel, D.; Perrin, B. S.; Raghuraman, V.; Rajyaguru, U.; Llamera, K. E.; Andrew, L.; Anderson, A. S.; Hovius, J. W.; Liberator, P. A. T.; Simon, R.; Hao, L.
10.1101/2023.11.30.568280 — genomics — Posted on 2023-12-01
4507 Digital telomere measurement by long-read sequencing distinguishes healthy aging from disease
Sanchez, S. E.; Gu, J.; Golla, A.; Martin, A.; Shomali, W.; Hockemeyer, D.; Savage, S.; Artandi, S.
10.1101/2023.11.29.569263 — genetics — Posted on 2023-12-01
4510 The historical ecological background of West Nile virus in Portugal provides One Health opportunities into the future
Geraldes, M. A.; Cunha, M. V.; Godinho, C.; Faustino de Lima, R.; Giovanetti, M.; Lourenco, J.
10.1101/2023.11.30.569416 — ecology — Posted on 2023-12-01
4511 Up-regulation of Retrograde Response in yeast increases glycerol and reduces ethanol during wine fermentation
Garrigos, V.; Vallejo, B.; Molla-Marti, E.; Picazo, C.; Peltier, E.; Marullo, P.; Matallana, E.; Aranda, A.
10.1101/2023.12.01.568406 — microbiology — Posted on 2023-12-01
4512 Epithelial organoid supports resident memory CD8 T cell differentiation
Ulibarri, M.; Lin, Y.; Ramprashad, J. R.; Han, G.; Hasan, M. H.; Mithila, F. J.; Ma, C.; Gopinath, S.; Zhang, N.; Milner, J. J.; Beura, L.
10.1101/2023.12.01.569395 — immunology — Posted on 2023-12-01
4513 Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis
Ehinger, Y.; Laguesse, S.; Phamluong, K.; Salvi, A.; Hoisington, Z. W.; Soneja, D.; Sei, Y. J.; Nakamura, K.; Ron, D.
10.1101/2023.11.29.569312 — neuroscience — Posted on 2023-12-01
4514 Increased levels of circulating methylglyoxal have no consequence for cerebral microvascular integrity and cognitive function in young healthy mice
Berends, E.; Vangrieken, P.; Amiri, N.; van de Waarenburg, M. P. H.; Scheijen, J. L. J. M.; Hermes, D. J. H. P.; van Oostenbrugge, R. J.; Schalkwijk, C. G.; Foulquier, S.
10.1101/2023.11.30.568559 — neuroscience — Posted on 2023-12-01
4515 A layer-specific model of cortical sensory aging
Liu, P.; Doehler, J.; Henschke, J. U.; Northall, A.; Serian, A.; Schwarzkopf, D. S.; Speck, O.; Pakan, J. M. P.; Kuehn, E.
10.1101/2023.12.01.567841 — neuroscience — Posted on 2023-12-01
4517 MHC-Fine: Fine-tuned AlphaFold for Precise MHC-Peptide Complex Prediction
Glukhov, E.; Kalitin, D.; Stepanenko, D.; Zhu, Y.; Nguen, T.; Jones, G.; Simmerling, C.; Mitchell, J. C.; Vajda, S.; Dill, K. A.; Padhorny, D.; Kozakov, D.
10.1101/2023.11.29.569310 — bioinformatics — Posted on 2023-12-01
4518 Diet-induced changes in metabolism influence immune response and viral shedding dynamics in Jamaican fruit bats
Falvo, C.; Crowley, D.; Benson, E.; Hall, M.; Schwarz, B.; Bohrnsen, E.; Ruiz-Aravena, M.; Hebner, M.; Ma, W.; Schountz, T.; Rynda-Apple, A.; Plowright, R.
10.1101/2023.12.01.569121 — ecology — Posted on 2023-12-01
4521 A plastidial DEAD box RNA helicase plays a critical role in high light acclimation by modulating ribosome biogenesis in Chlamydomonas reinhardtii
Djouani-Tahri, E. B.; Nellaepalli, S.; Auroy, P.; Billon, E.; Burlacot, A.; Chaux-Jukic, F.; Cuine, S.; Epting, V.; Huleux, M.; Ghysels, B.; Schulz-Raffelt, M.; Te, I.; Brugiere, S.; Coute, Y.; Takahashi, Y.; Li-Beisson, Y.; Peltier, G.
10.1101/2022.05.16.492170 — plant biology — Posted on 2023-12-01
4522 A Mouse Model of the Protease Activated Receptor 4 (PAR4) Pro310Leu Variant has Reduced Platelet Reactivity
Han, X.; Knauss, E. A.; de la Fuente, M.; Li, W.; Conlon, R. A.; LePage, D. F.; Jiang, W.; Renna, S. A.; McKenzie, S. E.; Nieman, M. T.
10.1101/2023.12.01.569075 — physiology — Posted on 2023-12-01
4525 Accurate long-read transcript discovery and quantification at single-cell resolution with Isosceles
Kabza, M.; Ritter, A.; Byrne, A.; Sereti, K.; Le, D.; Stephenson, W.; Sterne-Weiler, T.
10.1101/2023.11.30.566884 — bioinformatics — Posted on 2023-12-01
4527 Identification of conserved gene expression programs activated in multiple modes of torpor across vertebrate clades.
Weir, K.; Blackshaw, S.; Vega, N.; Busa, V.; Sajdak, B.; Kallestad, L.; Merriman, D.; Palczewski, K.; Carroll, J.
10.1101/2023.11.29.569284 — physiology — Posted on 2023-12-01
4532 Gut Microbiome Dynamics and Predictive Value in Hospitalized COVID-19 Patients: A Comparative Analysis of Shallow and Deep Shotgun Sequencing
Kopera, K.; Gromowski, T.; Wydmanski, W.; Skonieczna-Zydecka, K.; Muszynska, A.; Zielinska, K.; Wierzbicka-Wos, A.; Kaczmarczyk, M.; Kadaj-Lipka, R.; Cembrowska-Lech, D.; Januszkiewicz, K.; Koftis, K.; Witkiewicz, W.; Nalewajska, M.; Feret, W.; Marlicz, W.; Loniewski, I.; Labaj, P. P.; Rydzewska, G.; Kosciolek, T.
10.1101/2023.11.29.568526 — bioinformatics — Posted on 2023-12-01
4533 AutoGVP: a dockerized workflow integrating ClinVar and InterVar germline sequence variant classification
Kim, J.; Naqvi, A. S.; Corbett, R. J.; Kaufman, R. S.; Vaksman, Z.; Brown, M. A.; Miller, D. P.; Phul, S.; Geng, Z.; Storm, P. B.; Resnick, A. C.; Stewart, D. R.; Rokita, J. L.; Diskin, S. J.
10.1101/2023.11.29.569103 — bioinformatics — Posted on 2023-12-01
4537 Imitating the 'breeder's eye': predicting grain yield from measurements of non-yield traits
Jin, H.; Tross, M. C.; Tan, R.; Newton, L.; Mural, R. V.; Yang, J.; Thompson, A. M.; Schnable, J. C.
10.1101/2023.11.29.568906 — genetics — Posted on 2023-12-01
4538 Induced responses contribute to rapid plant adaptation to herbivory
Malacrino, A.; Böttner, L.; Nouere, S.; Huber, M.; Schäfer, M.; Xu, S.
10.1101/2022.11.24.517793 — evolutionary biology — Posted on 2023-12-01
4539 DNA Double-Strand Break Movement in Heterochromatin Depends on the Drosophila Histone Acetyltransferase Gcn5.
Kendek, A.; Sandron, A.; Lambooij, J.-P.; Colmenares, S. U.; Sobrevals Alcaraz, P.; van Es, R.; Pociunaite, S. M.; Gooijers, I.; de Groot, L.; Karpen, G.; Janssen, A.
10.1101/2023.11.30.569406 — cell biology — Posted on 2023-12-01
4540 Loss of cholesterol in Junctional Epidermolysis Bullosa skin identifies a key role for Laminin-332 in actomyosin mediated cholesterol transport
Jones, E. M.; Camera, E.; Parzymies, P.; Marsh, S. T.; O'Shaughnessy, R. F.; Aumailley, M.; McGrath, J. A.; O'Toole, E. A.; Caley, M. P.
10.1101/2023.09.10.557030 — cell biology — Posted on 2023-12-01
4543 AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress
Torres Acosta, M. A.; Mambetsariev, N.; Flores, C. P. R.; Helmin, K. A.; Liu, Q.; Joudi, A. M.; Morales-Nebreda, L.; Gurkan, J.; Cheng, K.; Abdala-Valencia, H.; Weinberg, S. E.; Singer, B. D.
10.1101/2023.11.29.568904 — immunology — Posted on 2023-12-01
4544 SPINAL V1 INHIBITORY INTERNEURON CLADES DIFFER IN BIRTHDATE, PROJECTIONS TO MOTONEURONS AND HETEROGENEITY
Worthy, A. E.; Anderson, J. T.; Lane, A. R.; Gomez-Perez, L.; Wang, A. A.; Griffith, R. W.; Rivard, A. F.; Bikoff, J. B.; Alvarez, F. J.
10.1101/2023.11.29.569270 — neuroscience — Posted on 2023-12-01
4548 Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development
Yuan, T.; Wang, Y.; Jin, Y.; Yang, H.; Xu, S.; Zhang, H.; Chen, Q.; Li, N.; Ma, X.; Song, H.; Peng, C.; Geng, Z.; Dong, J.; Duan, G.; Sun, Q.; Yang, Y.; Yang, F.; Huang, Z.
10.1101/2023.03.16.532982 — neuroscience — Posted on 2023-12-01
4549 Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease
Levites, Y.; Dammer, E. B.; Ran, Y.; Tsering, W.; Duong, D.; Abreha, M.; Gadhavi, J.; Lolo, K.; Trejo-Lopez, J.; Phillips, J. L.; Iturbe, A.; Erqiuzi, A.; Moore, B. D.; Ryu, D.; Natu, A.; Dillon, K. D.; Torrellas, J.; Moran, C.; Ladd, T. B.; Afroz, K. F.; Islam, T.; Jagirdar, J.; Funk, C. C.; Robinson, M.; Borchelt, D. R.; Ertekin-Taner, N.; Kelly, J. W.; Heppner, F. L.; Johnson, E. C.; McFarland, K.; Levey, A. L.; Prokop, S.; Seyfried, N. T.; Golde, T. E.
10.1101/2023.11.29.568318 — neuroscience — Posted on 2023-12-01
4550 Metabolic abnormalities in the bone marrow cells of young offspring born to obese mothers
Phillips, E. A.; Alharithi, Y. J.; Kadam, L.; Coussens, L. M.; Kumar, S.; Maloyan, A.
10.1101/2023.11.29.569274 — physiology — Posted on 2023-12-01
4551 Frustraevo: A Web Server To Localize And Quantify The Conservation Of Local Energetic Frustration In Protein Families
Parra, R. G.; Freiberger, M. I.; Poley-Gil, M.; Fernandez-Martin, M.; Radusky, L. G.; Wolynes, P. G.; Ferreiro, D. U.; Valencia, A.
10.1101/2023.11.29.569273 — bioinformatics — Posted on 2023-12-01
4553 Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
Yaghmaeian Salmani, B.; Lahti, L.; Gillberg, L.; Jacobsen, J. K.; Mantas, I.; Svenningsson, P.; Perlmann, T.
10.1101/2023.06.05.543445 — neuroscience — Posted on 2023-12-01
4554 The pathogenic coronatine toxin hijacks host redox signalling to suppress plant immunity
Frungillo, L.; Oka, N.; Lee, S.-U.; Nomoto, M.; Yun, B.-W.; Tada, Y.; Spoel, S. H.
10.1101/2023.12.01.569535 — plant biology — Posted on 2023-12-01
4556 Reconstructing oral cavity tumor evolution through brush biopsy
John, E.; Lesluyes, T.; Baker, T.; Tarabichi, M.; Gillenwater, A.; Wang, J. R.; Van Loo, P.; Zhao, X.
10.1101/2023.11.29.569216 — genomics — Posted on 2023-12-01
4558 Profound seizure suppression and disease modification by targeting JAK1, a key driver of a pro-epileptogenic gene network.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Espina, J. E. C.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A. S.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-12-01
4559 Protein tyrosine phosphatase receptor kappa regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity
Gilglioni, E. H.; Li, A.; Saint-Pierre Wijckmans, W.; Shen, T.-K.; Perez-Chavez, I.; Hovhannisyan, G.; Lisjak, M.; Negueruela, J.; Vandenbempt, V.; Bauza-Martinez, J.; Herranz, J. M.; Ezerina, D.; Demine, S.; Feng, Z.; Vignane, T.; Otero-Sanchez, L.; Lambertucci, F.; Prasnicka, A.; Deviere, J.; Hay, D. C.; Encinar, J. A. N.; Singh, S. P.; Messens, J.; Filipovic, M. R.; Sharpe, H. J.; Trepo, E.; Wu, W.; Gurzov, E. N.
10.1101/2023.12.01.569004 — cancer biology — Posted on 2023-12-01
4560 Strawberry phenotypic plasticity in flowering time is driven by interaction between genetic loci and temperature
Prohaska, A.; Petit, A.; Lesemann, S.; Rey-Serra, P.; Mazzoni, L.; Masny, A.; Sanchez-Sevilla, J. F.; Potier, A.; Gaston, A.; Klamkowski, K.; Rothan, C.; Mezzetti, B.; Amaya, I.; Olbricht, K.; Denoyes, B.
10.1101/2023.11.29.569202 — genetics — Posted on 2023-12-01
4561 Modeling aging and retinal degeneration with mitochondrial DNA mutation burden.
Sturgis, J.; Singh, R.; Caron, Q.; Samuels, I. S.; Shiju, T. M.; Mukkara, A.; Freedman, P.; Bonilha, V. L.
10.1101/2023.11.30.569464 — cell biology — Posted on 2023-12-01
4563 3D structure of fibroblasts and macrophages in the healthy and cryo-ablated heart
Fernandez, M. C.; Wülfers, E. M.; Madl, J.; Feliz, S. P.; Kohl, P.; Zgierski-Johnston, C. M.; Schneider-Warme, F.
10.1101/2023.11.30.569388 — cell biology — Posted on 2023-12-01
4565 Predicting hypersensitivity and comorbid depressive-like behavior in late stages of joint disease using early weight bearing deficit
Hestehave, S.; Florea, R.; Fedorec, A. J. H.; Jevic, M.; Mercy, L.; Wright, A.; Morgan, O. B.; Brown, L. A.; Peirson, S. N.; Geranton, S. M.
10.1101/2023.11.29.569246 — neuroscience — Posted on 2023-12-01
4566 Multiplexed tumor profiling with generative AI accelerates histopathology workflows and improves clinical predictions
Pati, P.; Karkampouna, S.; Bonollo, F.; Comperat, E.; Radic, M.; Spahn, M.; Martinelli, A.; Wartenberg, M.; Kruithof-de Julio, M.; Rapsomaniki, M. A.
10.1101/2023.11.29.568996 — bioinformatics — Posted on 2023-12-01
4567 A low-cost, AI-powered Measurement Verification and Reporting System for growing trees with smallholder farmers
Amoah, E. I.; McCloskey, P.; Ouedrago, R. S.; Chelal, J.; Akuleut, C.; Mwambumba, B. I.; Meli, B. K.; Oyudi, C. A.; Kibwamga, E. S.; Cleophas, E. K.; Ochola, F. O.; Wangiru, C. N.; Morang'a, K.; Mushira, L. W.; Maboke, M. K.; Titus, N. S.; Oltimbao, S. L.; Odawa, S. A.; Hughes, D. P.
10.1101/2023.11.29.569237 — ecology — Posted on 2023-12-01
4568 MAIT cells drive chronic inflammation in a genetically diverse murine model of spontaneous colitis.
Loh, L.; Orlicky, D.; Spengler, A.; Levens, C.; Celli, S.; Domenico, J.; Klarquist, J.; Onyiah, J.; Matsuda, J.; Kuhn, K. A.; Gapin, L.
10.1101/2023.11.29.569225 — immunology — Posted on 2023-12-01
4573 Spatiotemporal Metabolic Responses to Water Deficit Stress in Distinct Leaf Cell-types of Poplar
Balasubramanian, V. K.; Velickovic, D.; Rubio Wilhelmi, M. D. M.; Anderton, C. R.; Stewart, N. C.; DiFazio, S.; Blumwald, E.; Ahkami, A. H.
10.1101/2023.11.30.569476 — plant biology — Posted on 2023-12-01
4575 Editing cis-regulatory elements towards generating rice stomatal morphological variation for adaptation to broad and dynamic environments
Karavolias, N. G.; Patel-Tupper, D.; Cruz, A. G.; Litvak, L.; Lieberman, S. E.; Tjahjadi, M.; Niyogi, K. K.; Cho, M.-J.; Staskawicz, B.
10.1101/2023.11.29.569268 — plant biology — Posted on 2023-12-01
4577 Warm temperature and mild water stress cooperatively promote root elongation
Hayes, S.; Leong, C. K.; Zhang, W.; Lamain, M.; Lamers, J.; de Zeeuw, T.; Verstappen, F.; Hiltbrunner, A.; Testerink, C.
10.1101/2023.11.30.569400 — plant biology — Posted on 2023-12-01
4578 Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana
Dias, M. G.; Doss, B.; Rawat, A. R.; Siegel, K. R.; Mahathanthrige, T.; Sklenar, J.; Derbyshire, P.; Dharmasena, T.; Cameron, E.; Zipfel, C.; Menke, F.; Monaghan, J.
10.1101/2023.11.29.569073 — plant biology — Posted on 2023-12-01
4583 Convergent evolution of desiccation tolerance in grasses
Marks, R. A.; Van Der Pas, L.; Schuster, J.; VanBuren, R.
10.1101/2023.11.29.569285 — plant biology — Posted on 2023-12-01
4585 Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival
Krishnamurthy, A.; Lee, A. S.; Bayin, N. S.; Stephen, D. N.; Nasef, O.; Lao, Z.; Joyner, A. L.
10.1101/2023.11.30.569445 — developmental biology — Posted on 2023-12-01
4586 Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway.
Bose, M.; Suresh, V.; Mishra, U.; Talwar, I.; Yadav, A.; Biswas, S.; Hippenmeyer, S.; Tole, S.
10.1101/2023.11.30.569337 — neuroscience — Posted on 2023-12-01
4587 The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation
Rivera, C. C.; Price, R.; Fortuna, R. P.; Li, C.; Do, C.; Shinkle, J.; Ghilotti, M. G.; Shi, X.; Kirby, L. G.; Smith, G. M.; Unterwald, E. M.
10.1101/2023.11.29.569314 — neuroscience — Posted on 2023-12-01
4588 Mu-opioid receptor knockout on Foxp2-expressing neurons leads to reduced aversion-resistant reward seeking
Carvour, H. M.; Roemer, C. A.; Underwood, D. P.; Padilla, E. S.; Sandoval, O.; Robertson, M.; Miller, M.; Parsadanyan, N.; Perry, T. W.; Radke, A. K.
10.1101/2023.11.29.569252 — neuroscience — Posted on 2023-12-01
4589 Inhibitory fear memory engram in the mouse central lateral amygdala
Hou, W.-H.; Jariwala, M.; Wang, K.-Y.; Seewald, A.; Lin, Y.-L.; Ricci, A.; Ferraguti, F.; Lien, C.-C.; Capogna, M.
10.1101/2023.11.30.565632 — neuroscience — Posted on 2023-12-01