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Archive, 2023-07

3 Gene inversion triggered origination of brackish archaeal heterotrophs in the aftermath of the Cryogenian Snowball Earth
Fan, L.; Xu, B.; Chen, S.; Liu, Y.; Li, F.; Xie, W.; Prabhu, A.; Zou, D.; Wan, R.; Li, H.; Liu, H.; Liu, Y.; Kao, S.-J.; Chen, J.; Zhu, Y.; Rinke, C.; Li, M.; Zhu, M.; Zhang, C.
10.1101/2022.09.25.509439 — evolutionary biology — Posted on 2023-07-31
5 Transcriptomics elucidates metabolic regulation and functional promoters in the basidiomycete red yeast Xanthophyllomyces dendrorhous CBS 6938
Tobin, E. E.; Collins, J. H.; Marsan, C. B.; Nadeau, G. T.; Mori, K.; Lipzen, A.; Mondo, S.; Grigoriev, I. V.; Young, E. M.
10.1101/2023.07.31.551333 — synthetic biology — Posted on 2023-07-31
6 The Role of C-to-U RNA Editing in Human Biodiversity
Van Norden, M. C.; Falls, Z.; Mandloi, S.; Segal, B.; Baysal, B.; Samudrala, R.; Elkin, P. L.
10.1101/2023.07.31.550344 — bioinformatics — Posted on 2023-07-31
9 Saponin Nanoparticle Adjuvants Incorporating Toll-Like Receptor Agonists Improve Vaccine Immunomodulation
Ou, B. S.; Baillet, J.; Filsinger Interrante, M. V.; Adamska, J. Z.; Zhou, X.; Saouaf, O.; Yan, J.; Klich, J.; Jons, C. K.; Meany, E.; Valdez, A. S.; Carter, L.; Pulendran, B.; King, N. P.; Appel, E.
10.1101/2023.07.16.549249 — bioengineering — Posted on 2023-07-31
10 Rapid and visual detection of Schistosoma japonicum circulating nucleic acids by CRISPR-Cas12a
Li, Q.; Yang, S.; Cheng, M.; Xing, C.; Wang, X.; Zhu, Y.; Tang, Y.; Cheng, W.; Shen, J.; Du, Y.
10.1101/2023.07.31.551221 — bioengineering — Posted on 2023-07-31
11 Structure of Orthoreovirus RNA Chaperone σNS, a Component of Viral Replication Factories
Zhou, B.; Hu, L.; Kuandal, S.; Lee, C.; Somoulay, X.; Sankaran, B.; Taylor, G. M.; Dermody, T. S.; Prasad, B. V.
10.1101/2023.07.31.551319 — biochemistry — Posted on 2023-07-31
12 Metabolomic changes associated with acquired resistance to Ixodes scapularis
Cui, Y.; Matias, J.; Tang, X.; Cibichakravarthy, B.; DePonte, K.; Wu, M.-J.; Fikrig, E.
10.1101/2023.07.31.551287 — biochemistry — Posted on 2023-07-31
15 Extrachromosomal Telomeres Derived from Excessive Strand Displacements
Lee, J.; Lee, J.; Sohn, E. J.; Taglialatela, A.; O'Sullivan, R. J.; Ciccia, A.; Min, J.
10.1101/2023.07.31.551186 — biochemistry — Posted on 2023-07-31
17 Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism
Gilsbach, B. K.; Ho, F. Y.; Riebenbauer, B.; Zhang, X.; Guaitoli, G.; Kortholt, A.; Gloeckner, C. J.
10.1101/2023.07.31.549909 — biochemistry — Posted on 2023-07-31
19 Cyanobacterial α-carboxysome carbonic anhydrase is allosterically regulated by the Rubisco substrate RuBP
Pulsford, S. B.; Outram, M. A.; Forster, B.; Rhodes, T.; Williams, S. J.; Badger, M. R.; Price, G. D.; Jackson, C. J.; Long, B. M.
10.1101/2023.07.31.551272 — molecular biology — Posted on 2023-07-31
20 Sister chromatid cohesion halts DNA loop expansion
Bastie, N.; Chapard, C.; Nejmi, S.; Mboumba, H.; thierry, a.; Beckouet, F.; Koszul, R.
10.1101/2023.07.31.551217 — molecular biology — Posted on 2023-07-31
22 ZNF512B binds RBBP4 via a variant NuRD interaction motif and aggregates chromatin in a NuRD complex-independent manner
Wunderlich, T. M.; Deshpande, C.; Paasche, L. W.; Friedrich, T.; Diegmueller, F.; Daus, N.; Naseer, H.; Stebel, S. E.; Leers, J.; Lan, J.; Trinh, V. T.; Vazquez, O.; Butter, F.; Bartkuhn, M.; Mackay, J. P.; Hake, S. B.
10.1101/2023.07.31.551264 — molecular biology — Posted on 2023-07-31
23 Antibodies halting motility in Mycoplasma pneumoniae reveal the dynamic nature of the adhesion complex
Kawamoto, A.; Vizarraga, D.; Marcos-Silva, M.; Martin, J.; Makino, F.; Miyata, T.; Roel, J.; Marcos, E.; Aparicio, D.; Fita, I.; Miyata, M.; Pinol, J.; Namba, K.; Kenri, T.
10.1101/2023.07.31.551205 — molecular biology — Posted on 2023-07-31
24 Salmonella Infantis, the emerging human multidrug resistant pathogen - a One Health perspective
Mattock, J.; Chattaway, M. A.; Hartman, H.; Dallman, T.; Smith, A.; Keddy, K.; Petrovska, L.; Manners, E.; Duze, S.; Smouse, S.; Tau, N. P.; Timme, R.; Baker, D.; Mather, A.; Wain, J.; Langridge, G.
10.1101/2023.07.28.549231 — microbiology — Posted on 2023-07-31
27 Sequencing and Culture-based Characterization of the Vaginal and Uterine Microbiota in Beef Cattle that Became Pregnant or Non-pregnant via Artificial Insemination
Webb, E. M.; Holman, D. B.; Schmidt, K. N.; Pun, B.; Sedivec, K. K.; Hurlbert, J. L.; Bochantin, K. A.; Ward, A. K.; Dahlen, C. R.; Amat, S.
10.1101/2023.07.31.551361 — microbiology — Posted on 2023-07-31
28 Astonishing diversity and multifaceted biological connections of Type IV restriction-modification systems
Bell, R. T.; Juozapaitis, J.; Songailiene, I.; Sahakyan, H.; Liegute, T.; Makarova, K. S.; Wolf, Y. I.; Siksnys, V.; Koonin, E. V.
10.1101/2023.07.31.551357 — microbiology — Posted on 2023-07-31
29 An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis
Nair, Z. J.; Gao, I. H.; Firras, A.; Chong, K. K. L.; Choo, P. Y.; Pethe, K.; Kline, K. A.
10.1101/2023.07.31.551240 — microbiology — Posted on 2023-07-31
32 Mass spectrometry-based multi-omics identifies metabolic signatures of sarcopenia in rhesus monkey skeletal muscle
Pergande, M. R.; Osterbauer, K. J.; Buck, K. M.; Roberts, D. S.; Wood, N. N.; Balasubramanian, P.; Mann, M. W.; Rossler, K.; Diffee, G. M.; Colman, R. J.; Anderson, R. M.; Ge, Y.
10.1101/2023.07.31.551315 — biochemistry — Posted on 2023-07-31
33 Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2
Bradshaw, W. J.; Kennedy, E. C.; Moreira, T.; Smith, L. A.; Chalk, R.; Katis, V. L.; Benesch, J. L.; Brennan, P. E.; Murphy, E. J.; Gileadi, O.
10.1101/2023.07.31.551266 — biochemistry — Posted on 2023-07-31
35 Expansion of profibrotic monocyte-derived alveolar macrophages in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19
Bailey, J. I.; Puritz, C. H.; Senkow, K. J.; Markov, N. S.; Diaz, E.; Jonasson, E.; Yu, Z.; Swaminathan, S.; Lu, Z.; Fenske, S.; Grant, R. A.; Abdala-Valencia, H.; Mylvaganam, R. J.; Miller, J.; Cumming, R. I.; Tighe, R. M.; Gowdy, K. M.; Kalhan, R.; Jain, M.; Bharat, A.; Kurihara, C.; San Jose Estepar, R.; San Jose Estepar, R.; Washko, G. R.; Shilatifard, A.; Sznajder, J. I.; Ridge, K. M.; Budinger, G. S.; Braun, R.; Misharin, A. V.; Sala, M. A.
10.1101/2023.07.30.551145 — immunology — Posted on 2023-07-31
36 Immunities Specific to Both of the M Protein Ectodomain and RBD Synergize to Confer Cross-protection against SARS-CoV-2 Infections
Tang, Y.; Tang, K.; Hu, Y.; Ye, Z.-W.; Luo, W.; Luo, C.; Cao, H.; Wang, R.; Liu, D.; Liu, C.; Ge, X.; Chen, Y.; Yuan, S.; Deng, L.
10.1101/2023.07.31.551223 — immunology — Posted on 2023-07-31
37 Noisy circumnutations facilitate self-organized shade avoidance in sunflowers
Nguyen, C.; Dromi, I.; Kempinski, A.; Gall, G. E. C.; Peleg, O.; Meroz, Y.
10.1101/2022.06.11.495747 — plant biology — Posted on 2023-07-31
39 The androgen receptor does not directly regulate the transcription of DNA damage response genes
Hasterok, S.; Scott, T. G.; Roller, D. G.; Spencer, A.; Dutta, A. B.; Sathyan, K. M.; Frigo, D. E.; Guertin, M. J.; Gioeli, D.
10.1101/2023.05.13.540653 — cancer biology — Posted on 2023-07-31
41 Automated system for training and assessing string-pulling behaviors in rodents
Jordan, G. A.; Vishwanath, A.; Holguin, G.; Bartlett, M. J.; Tapia, A. K.; Winter, G. M.; Sexauer, M. M.; Stopera, C. J.; Falk, T.; Cowen, S. L.
10.1101/2023.07.02.547431 — bioengineering — Posted on 2023-07-31
45 Locus coeruleus neuromelanin predicts ease of attaining and maintaining neural states of high attentiveness
Hussain, S.; Menchaca, I.; Shalchy, M. A.; Yaghoubi, K.; langley, j.; Seitz, A.; Hu, X.; Peters, M. A. K.
10.1101/2022.03.07.483289 — neuroscience — Posted on 2023-07-31
49 Taurine Supplementation Activates Growth Suppressive Mechanisms in Ovarian Cancer
Centeno, D.; Farsinejad, S.; Kochetkova, E.; Volpari, T.; Klupczynska - Gabryszak, A.; Kung, D.; Polotaye, T.; Hyde, E.; Greenberg, M.; Pavlovic, T.; Alshehri, S.; Sullivan, W.; Plewa, S.; Vakifahmetoglu-Norberg, H.; Monsma, F. J.; Muller, P. A. J.; Matysiak, J.; Zaborowski, M.; DiFeo, A.; Andres-Martin, L.; Norberg, E.; Iwanicki, M.
10.1101/2023.02.24.529893 — cancer biology — Posted on 2023-07-31
56 Genomic data suggest parallel dental vestigialization within the xenarthran radiation
Emerling, C. A.; Gibb, G. C.; Tilak, M.-K.; Hughes, J. J.; Kuch, M.; Duggan, A. T.; Poinar, H. N.; Nachman, M. W.; Delsuc, F.
10.1101/2022.12.09.519446 — evolutionary biology — Posted on 2023-07-31
57 Facultative symbiont virulence determines horizontal transmission rate without host strain specificity
Noh, S.; Larson, E. R.; Covitz, R. M.; Chen, A.; Mazumder, P. R.; Peck, R. F.; Hamilton, M. C.; Dettmann, R. A.
10.1101/2023.02.16.528903 — evolutionary biology — Posted on 2023-07-31
61 Time series scRNAseq analysis in mouse and human informs optimization of rapid astrocyte differentiation protocols.
Frazel, P.; Labib, D.; Fisher, T.; Brosh, R.; Pirianian, N.; Marchildon, A.; Boeke, J. D.; Fossati, V.; Liddelow, S. A.
10.1101/2021.12.07.471509 — neuroscience — Posted on 2023-07-31
62 Emergent neural dynamics and geometry for generalization in a transitive inference task
Kay, K.; Biderman, N.; Khajeh, R.; Beiran, M.; Cueva, C. J.; Shohamy, D.; Jensen, G.; Wei, X.-X.; Ferrera, V. P.; Abbott, L. F.
10.1101/2022.10.10.511448 — neuroscience — Posted on 2023-07-31
67 Energy Coupling and Stoichiometry of Zn2+/H+ Antiport by the Cation Diffusion Facilitator YiiP
Hussein, A.; Fan, S.; Lopez-Redondo, M. L.; Kenney, I.; Zhang, X.; Beckstein, O.; Stokes, D. L.
10.1101/2023.02.23.529644 — biophysics — Posted on 2023-07-31
69 SPLASH: a statistical, reference-free genomic algorithm unifies biological discovery
Chaung, K.; Baharav, T. Z.; Henderson, G.; Wang, P.; Zheludev, I. N.; Salzman, J.
10.1101/2023.07.17.549408 — genomics — Posted on 2023-07-31
70 SPLASH: a statistical, reference-free genomic algorithm unifies biological discovery
Chaung, K.; Baharav, T. Z.; Henderson, G.; Zheludev, I.; Wang, P. L.; Salzman, J.
10.1101/2022.06.24.497555 — genomics — Posted on 2023-07-31
73 Interaction of SCoV-2 NSP7 or NSP8 alone with NSP12 causes constriction of the RNA entry channel: Implications for novel RdRp inhibitor drug discovery
Singh, D.; Kushwaha, T.; Kulandaisamy, R.; Kumar, V.; Baswal, K.; Tiwari, S. H.; Ghorai, A.; Kumar, M.; Kumar, S.; Polamarasetty, A.; Sehgal, D.; Katika, M. R.; Gadde, S.; Cote, M.; Kayampeta, S. R.; Appaiahgari, M. B.; Inampudi, K. K.
10.1101/2023.07.26.550660 — molecular biology — Posted on 2023-07-31
74 Elucidating polymorphs of crystal structures with intensity-based hierarchical clustering analysis on multiple diffraction datasets
Matsuura, H.; Sakai, N.; Toma-Fukai, S.; Muraki, N.; Hayama, K.; Kamikubo, H.; Aono, S.; Kawano, Y.; Yamamoto, M.; Hirata, K.
10.1101/2022.09.13.507775 — molecular biology — Posted on 2023-07-31
75 A flexible high-throughput cultivation protocol to assess the response of individuals' gut microbiota to diet-, drug-, and host-related factors
Zünd, J. N.; Plüss, S.; Mujezinovic, D.; Menzi, C.; von Bieberstein, P. R.; de Wouters, T.; Lacroix, C.; Leventhal, G. E.; Pugin, B.
10.1101/2023.07.11.548549 — microbiology — Posted on 2023-07-31
77 Oligodendrocyte dynamics dictate individual performance outcomes of working memory training in mice
Shimizu, T.; Nayar, S. G.; Swire, M.; Jiang, Y.; Grist, M.; Kaller, M.; Sampaio Baptista, C.; Johansen-Berg, H.; Ogasawara, K.; Tohyama, K.; Li, H.; Richardson, W. D.
10.1101/2023.01.17.524381 — neuroscience — Posted on 2023-07-31
78 GSK3 inhibition improves skeletal muscle function and whole-body metabolism in the severe DBA/2J mdx mouse model
Marcella, B. M.; Hockey, B.; Braun, J. L.; Whitley, K. C.; Geromella, M. S.; Baranowski, R. W.; Watson, C. J.; Silvera, S.; Hamstra, S. I.; Wasilewicz, L. J.; Crozier, R. W.; Marais, A. A.; Vandenboom, R.; Roy, B. D.; MacNeil, A. J.; MacPherson, R. E.; Fajardo, V.
10.1101/2022.02.16.480726 — physiology — Posted on 2023-07-31
79 Comprehensive analysis of the transcription factor REST regulatory networks in IDH-mutant and IDH-wild type glioma
Perycz, M.; Dabrowski, M. J.; Jardanowska, M.; Roura, A.-J.; Gielniewski, B.; Stepniak, K.; Draminski, M.; Kaminska, B.; Wojtas, B.
10.1101/2022.07.28.501927 — cancer biology — Posted on 2023-07-31
81 Benchmarking DNA Isolation Methods for Marine Metagenomics Studies
Demkina, A.; Slonova, D.; Mamontov, V.; Konovalova, O.; Yurikova, D.; Rogozhin, V.; Belova, V.; Korostin, D.; Sutormin, D.; Severinov, K. V.; Isaev, A.
10.1101/2023.07.25.550485 — bioinformatics — Posted on 2023-07-31
84 Nanoscale analysis of human G1 and metaphase chromatin in situ
Chen, J. K.; Liu, T.; Cai, S.; Ruan, W.; Ng, C. T.; Shi, J.; Surana, U.; Gan, L.
10.1101/2023.07.31.551204 — cell biology — Posted on 2023-07-31
86 Major data analysis errors invalidate cancer microbiome findings
Gihawi, A.; Ge, Y.; Lu, J.; Puiu, D.; Xu, A.; Cooper, C. S.; Brewer, D. S.; Pertea, M.; Salzberg, S.
10.1101/2023.07.28.550993 — cancer biology — Posted on 2023-07-31
89 Mitochondrial Genome Diversity across the Subphylum Saccharomycotina
Wolters, J. F.; LaBella, A.; Opulente, D.; Rokas, A.; Hittinger, C. T.
10.1101/2023.07.28.551029 — genetics — Posted on 2023-07-31
93 Chitosan stimulates root hair callose deposition and inhibits root hair growth
Drs, M.; Haluska, S.; Skrabalkova, E.; Krupar, P.; Brejskova, L.; Muller, K.; Serrano, N.; Potocka, A.; Voxeur, A.; Vernhettes, S.; Ortmannova, J.; Caldarescu, G.; Fendrych, M.; Potocky, M.; Zarsky, V.; Pecenkova, T.
10.1101/2023.07.30.551171 — plant biology — Posted on 2023-07-31
94 Flavinated SDHA Underlies the Change in Intrinsic Optical Properties of Oral Cancers
Marumo, T.; Maduka, C. V.; Ural, E.; Apu, E. H.; Chung, S.-J.; van den Berg, N. S.; Zhou, Q.; Martin, B. A.; Rosenthal, E. L.; Shibahara, T.; Contag, C. H.
10.1101/2023.07.30.551184 — cancer biology — Posted on 2023-07-31
95 Mobile retroelements induced by hypomethylating agents are restricted to transpose in myeloid malignancies
Pavlova, S.; Krzyzankova, M.; Volakhava, A.; Smirnova, A.; Grigoreva, T.; Jaskova, Z.; Synackova, H.; Wahl, D.; Bohunova, M.; Cervinek, L.; Pospisilova, S.; Mamedov, I.; Plevova, K.
10.1101/2023.07.30.551176 — cancer biology — Posted on 2023-07-31
98 Immunometabolic cues recompose and reprogram the microenvironment around biomaterials
Maduka, C. V.; Schmitter-Sanchez, A. D.; Makela, A. V.; Ural, E.; Stivers, K. B.; Pope, H.; Kuhnert, M. M.; Habeeb, O. M.; Tundo, A.; Alhaj, M.; Kiselev, A.; Chen, S.; Olive, A. J.; Hankenson, K. D. D.; Narayan, R.; Park, S.; Elisseeff, J. H.; Contag, C. H.
10.1101/2023.07.30.551180 — bioengineering — Posted on 2023-07-31
99 Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn
Liebhoff, A.-M.; Venkataraman, T.; Morgenlander, W. R.; Na, M.; Kula, T.; Waugh, K.; Morrison, C.; Rewers, M.; Longman, R.; Round, J.; Elledge, S.; Ruczinski, I.; Langmead, B.; Larman, H. B.
10.1101/2023.07.30.551179 — bioengineering — Posted on 2023-07-31
100 Identification of Sequence Determinants for the ABHD14 Enzymes
Vaidya, K.; Rodrigues, G.; Gupta, S.; Devarajan, A.; Yeolekar, M.; Madhusudhan, M. S.; Kamat, S. S.
10.1101/2023.07.30.551196 — biochemistry — Posted on 2023-07-31
102 Genetic reprogramming by brief inhibition of the renin-angiotensin system in spontaneously hypertensive rats leads to persistently reduced kidney renin and low blood pressure.
Harrap, S.; Byars, S. G.; Prestes, P. R.; Suphapimol, V.; Takeuchi, F.; De Vries, N.; Maier, M.; Rosso Melo, M.; Balding, D.; Samani, N. J.; Allen, A. M.; Kato, N.; Wilkinson-Berka, J. L.; Charchar, F. J.
10.1101/2023.07.30.551193 — genetics — Posted on 2023-07-31
104 Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress
Liang, Y.; Wang, Y.; Zhang, X.; Jin, S.; Guo, Y.; Yu, Z.; Xu, X.; Shuai, Q.; Feng, Z.; Chen, B.; Liang, T.; Ao, R.; Li, J.; Zhang, J.; Cao, R.; Zhao, H.; Chen, Z.; Liu, Z.; Xie, J.
10.1101/2023.07.30.551130 — developmental biology — Posted on 2023-07-31
107 ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota
Cheng, M.-y.; Xu, B.; Sun, Y.; Wang, J.; Lu, Y.; Shi, C.; Pan, T.; Zhao, W.; Li, X.; Song, X.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Yang, D.; Wang, C.; Cao, X.
10.1101/2023.07.30.551192 — immunology — Posted on 2023-07-31
114 Spatial Omics Driven Crossmodal Pretraining Applied to Graph-based Deep Learning for Cancer Pathology Analysis
Azher, Z.; Fatemi, M.; Lu, Y.; Srinivasan, G.; Diallo, A.; Christensen, B.; Salas, L.; Kolling, F.; Perreard, L.; Palisoul, S.; Vaickus, L.; Levy, J.
10.1101/2023.07.30.551187 — pathology — Posted on 2023-07-31
115 Artificial Intelligence Helps to Predict Recurrence and Mortality for Prostate Cancer using Histology Images
Eminaga, O.; Saad, F.; Tian, Z.; Wolffgang, U.; Karakiewicz, P. I.; Ouellet, V.; Azzi, F.; Spieker, T.; Helmke, B. M.; Graefen, M.; Jiang, X.; Xing, L.; Witt, J. H.; Trudel, D.; Leyh-Bannurah, S.-R.
10.1101/2023.07.27.550781 — pathology — Posted on 2023-07-31
116 A transcriptome-wide meta-analysis reveals lack of cancer-cell intrinsic determinants of response to immune checkpoint blockade
Guo, Y. A.; Kulshrestha, T.; Chang, M. M.; Kassam, I.; Revkov, E.; Rizzetto, S.; Tan, A.; Tan, D.; Tan, I. B.; Jacobsen Skanderup, A.
10.1101/2023.07.30.551135 — cancer biology — Posted on 2023-07-31
117 Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry
Doktorova, M.; Symons, J. L.; Zhang, X.; Wang, H.-Y.; Schlegel, J.; Lorent, J. H.; Heberle, F. A.; Sezgin, E.; Lyman, E.; Levental, K. R.; Levental, I.
10.1101/2023.07.30.551157 — biophysics — Posted on 2023-07-31
118 Large-FOV 3D localization microscopy by spatially variant point spread function generation
Xiao, D.; Kedem Orange, R.; Opatovski, N.; Parizat, A.; Nehme, E.; Alalouf, O.; Shechtman, Y.
10.1101/2023.07.30.551150 — bioengineering — Posted on 2023-07-31
120 Global meta-analysis reveals overall benefits of silvopastoral systems for biodiversity
Perez-Alvarez, R.; Chara, J.; Snyder, L. D.; Bonatti, M.; Sieber, S.; Martin, E. A.
10.1101/2023.07.30.551160 — ecology — Posted on 2023-07-31
123 Murine classical monocyte subsets display distinct functions and fates
Trzebanski, S.; Kim, J.-S.; Larrossi, N.; Kancheva, D.; Bastos, J.; Haddad, M.; Aizik, D.; Kralova, J.; Gross-Vered, M.; Boura-Halfon, S.; Lapidot, T.; Alon, R.; Movahedi, K.; Jung, S.
10.1101/2023.07.29.551083 — immunology — Posted on 2023-07-31
127 Identification of 5-HT2A Receptor Signaling Pathways Responsible for Psychedelic Potential
Wallach, J.; Cao, A. B.; Calkins, M. M.; Heim, A. J.; Lanham, J. K.; Bonniwell, E. M.; Hennessey, J. J.; Bock, H. A.; Anderson, E. I.; Sherwood, A. M.; Morris, H.; de Klein, R.; Klein, A. K.; Cuccurazzu, B.; Gamrat, J.; Fannana, T.; Zauhar, R.; Halberstadt, A. L.; McCorvy, J. D.
10.1101/2023.07.29.551106 — neuroscience — Posted on 2023-07-31
129 Investigating the mechanisms underlying Bortezomib resistance
Zafeiropoulou, K.; Kalampounias, G.; Alexis, S.; Anastasopoulos, D.; Symeonidis, A.; Katsoris, P.
10.1101/2023.07.29.551081 — cancer biology — Posted on 2023-07-31
131 Acoustic wave-induced stroboscopic optical mechanotyping of adherent cells
Combriat, T.; Olsen, P. A.; Lastad, S. B.; Malthe-Sorenssen, A.; Krauss, S.; Dysthe, D. K.
10.1101/2023.07.29.551092 — biophysics — Posted on 2023-07-31
138 Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
Carpenter, M. A.; Temiz, N. A.; Ibrahim, M.; Jarvis, M.; Brown, M.; Argyris, P.; Brown, W.; Yee, D.; Harris, R. S.
10.1101/2022.04.26.489523 — cancer biology — Posted on 2023-07-31
141 Proneural genes form a combinatorial code to diversify neocortical neural progenitor cells
Moffat, A.; Oproescu, A.-M.; Okawa, S.; Han, S.; Vasan, L.; Ghazale, H.; Dennis, D. J.; Zinyk, D.; Guillemot, F.; del Sol, A.; Schuurmans, C.
10.1101/2023.07.29.551096 — developmental biology — Posted on 2023-07-31
142 Wall teichoic acid substitution with glucose governs phage susceptibility of Staphylococcus epidermidis
Beck, C. R.; Krusche, J.; Notaro, A.; Walter, A.; Krankel, L.; Vollert, A.; Stemmler, R.; Wittmann, J.; Schaller, M.; Slavetinsky, C. J.; Mayer, C.; De Castro, C.; Peschel, A.
10.1101/2023.07.27.550822 — microbiology — Posted on 2023-07-31
144 Heat stress induces a developmental shift from type-V to type-IV trichome dependent on jasmonate signaling in tomato
Säbel, R.; Brand, A.; Bergau, N.; Balcke, G.; Syrowatka, F.; Püffeld-Raorane, M.; Hause, B.; Tissier, A. F.
10.1101/2023.07.28.551053 — plant biology — Posted on 2023-07-31
146 Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers
Jessen, M.; Gertzmann, D.; Liss, F.; Zenk, F.; Baehner, L.; Schoeffler, V.; Ade, C. P.; von Eyss, B.; Gaubatz, S.
10.1101/2023.07.27.550917 — cancer biology — Posted on 2023-07-31
148 The scale-invariant covariance spectrum of brain-wide activity
Wang, Z.; Mai, W.; Chai, Y.; Qi, K.; Ren, H.; Shen, C.; Zhang, S.; Tan, G.; Hu, Y.; Wen, Q.
10.1101/2023.02.23.529673 — neuroscience — Posted on 2023-07-31
151 Square beams for optimal tiling in TEM
Chua, E. Y. D.; Alink, L. M.; Kopylov, M.; de Marco, A.
10.1101/2023.07.29.551095 — biophysics — Posted on 2023-07-30
152 Evaluating cytotoxicity and genotoxicity of oil extracted from visceral fat of Caiman yacare (Daudin, 1802) in chinese hamster lung fibroblast in vitro.
Azevedo, L. P.; Rios-Santos, F.; Branco, C. B.; Pressinotti, L. N.; Reis, E. d. M.; Filho, S. V.; Martins, D. T. d. O.; de Vasconcelos, L. G.; Ferraz, R. H. d. S.; Mesquita, F. V.; Silva, W. d. A.; Junior, P. T. d. S.
10.1101/2023.07.28.551009 — cell biology — Posted on 2023-07-30
155 Distribution of carbon monoxide (CO) in several tissues from Atlantic bottlenose dolphins (Tursiops truncatus)
Tift, M. S.; Litzenberg, K.; Herrmann, K.; Cotoia, A.; Jackson, O.; Keenan, T.; Kezar, K.; Pearson, A.; McLellan, W.; Pabst, D. A. S.
10.1101/2023.07.28.551019 — physiology — Posted on 2023-07-30
157 Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targeting of WRN and ATR
Zong, D.; Koussa, N. C.; Cornwell, J. A.; Pankajam, A. V.; Kruhlak, M.; Wong, N.; Chari, R.; Cappell, S. D.; Nussenzweig, A.
10.1101/2023.07.28.550976 — cancer biology — Posted on 2023-07-30
160 Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in hepatic stellate cells
Sun, C.; Zhou, C.; Daneshvar, K.; Kratkiewicz, A. J.; Ben Saad, A.; Hess, A.; Chen, J. Y.; Pondick, J. V.; York, S. R.; Li, W.; Moran, S. P.; Gentile, S.; Ur Rahman, R.; Li, Z.; Sparks, R.; Habboub, T.; Kim, B.-M.; Choi, M.; Affo, S.; Schwabe, R. F.; Popov, Y. V.; Mullen, A. C.
10.1101/2023.07.29.551032 — cell biology — Posted on 2023-07-30
163 Hawkes process modeling quantifies complicated firing behaviors of cortical neurons during sleep and wakefulness
Kanda, T.; Aritake, T.; Ohyama, K.; Vogt, K. E.; Makino, Y.; McHugh, T.; Hino, H.; Akaho, S.; Murata, N.
10.1101/2023.07.29.550297 — neuroscience — Posted on 2023-07-30
164 A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets
Calebiro, D.; O'Brien, S. L.; Tripp, E.; Smith, G.; Boufersaoui, A.; Roberts, J.; Pike, J. A.; Correia, J.; Miljus, T. A.; Tennant, D. A.; Hudson, B. D.; Milligan, G.; Gerhart-Hines, Z.; Schwartz, T. W.
10.1101/2023.07.28.550805 — pharmacology and toxicology — Posted on 2023-07-30
169 Spring reproductive success influences autumnal malarial load in a passerine bird
Pigeault, R.; Cozzarolo, C.-S.; Wassef, J.; Gremion, J.; Bastardot, M.; Glaizot, O.; Christe, P.
10.1101/2023.07.28.550923 — ecology — Posted on 2023-07-30
172 Bacterial risk evaluation of widely consumed fast foods by the younger population in Bangladesh and its potential health effects
Masud, L. B.; Hossain, M. I.; Faruk, M. O.; Tuha, M. A. S. M.; Akash, S. R.; Islam, K. R.; Sahabuddin, M.; Ali, M. S.
10.1101/2023.07.30.551147 — microbiology — Posted on 2023-07-30
176 Multiple Receptor Tyrosine Kinases Regulate Dengue Infection of Hepatocytes
Bourgeois, N. M.; Wei, L.; Ho, N. N. T.; Neal, M. L.; Seferos, D.; Tongogara, T.; Mast, F. D.; Aitchison, J. D.; Kaushansky, A.
10.1101/2023.07.30.549949 — systems biology — Posted on 2023-07-30
177 The epigenetic response of mouse brown adipose tissue to cold stress: histone proteoform, DNA methylation, and RNA expression
Taylor, B. C.; Steinthal, L. H.; Dias, M.; Yalamanchili, H. K.; Ochsner, S. A.; Zapata, G. E.; Mehta, N. R.; McKenna, N. J.; Young, N. L.; Nuotio-Antar, A. M.
10.1101/2023.07.30.551059 — systems biology — Posted on 2023-07-30
178 Brd4-Nutm1 fusion gene initiates NUT carcinoma in vivo
Zheng, D.; El Negiry, A. A. M.; Bendahou, M. A.; Xie, L.; Tsoi, M. F.; Gu, B.
10.1101/2023.07.29.551125 — cancer biology — Posted on 2023-07-30
185 Genetic consequences of improved river connectivity in brown trout (Salmo trutta, L.)
Moccetti, P.; Dodd, J. R.; Joyce, D. A.; Nunn, A. D.; Gillespie, B.; Bolland, J. D.
10.1101/2023.07.30.551162 — evolutionary biology — Posted on 2023-07-30
190 Missing microbial eukaryotes and misleading meta-omic conclusions
Krinos, A. I.; Mars Brisbin, M.; Hu, S. K.; Cohen, N. R.; Rynearson, T. A.; Follows, M. J.; Schulz, F.; Alexander, H.
10.1101/2023.07.30.551153 — microbiology — Posted on 2023-07-30
192 Metagenomics untangles metabolic adaptations of Antarctic endolithic 1 bacteria at the fringe of habitability
COLEINE, C.; Albanese, D.; Ray, A.; DELGADO BAQUERIZO, M.; Stajich, J. E.; Williams, T.; Larsen, S.; Tringe, S.; Pennacchio, C.; Ferrari, B. C.; Donati, C.; Selbmann, L.
10.1101/2023.07.30.551190 — microbiology — Posted on 2023-07-30
194 Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome
Ryan, M. J.; Raby, E.; Masuda, R.; Lodge, S.; Nitschke, P.; Maker, G. L.; Wist, J.; Fear, M. W.; Holmes, E.; Nicholson, J.; Gray, N.; Whiley, L.; Wood, F. M.
10.1101/2023.07.28.550938 — systems biology — Posted on 2023-07-30
195 The Endosomal pH Regulator NHE6 is Required for Insulin-Stimulated Glucose Uptake in Adipocytes
Mekile, A. X.; Makena, M. R.; Gupta, R.; White, C. J.; Bowman, R. W.; Patnayak, R. L.; Lorenzo, D. N.; Rao, R.
10.1101/2023.07.30.551163 — physiology — Posted on 2023-07-30
196 Highly effective gene inactivation in tetraploid Xenopus laevis with low-temperature-active engineered Cas12a
Yun, S.; Kim, S.; Hong, J.; Choi, J.; Shin, J.-S.; Choi, S.; Lee, H.-S.; Cho, S. W.; Park, T. J.; Kwon, T.
10.1101/2023.07.30.550813 — bioengineering — Posted on 2023-07-30
197 The pathogenic T42A mutation in SHP2 rewires interaction specificity and enhances signaling
van Vlimmeren, A. E.; Voleti, R.; Chartier, C. A.; Jiang, Z.; Karandur, D.; Shah, N. H.
10.1101/2023.07.10.548257 — biochemistry — Posted on 2023-07-30
202 AlphaFold2 modeling and molecular dynamics simulations of an intrinsically disordered protein
Guo, H.-B.; Huntington, B.; Perminov, A.; Smith, K.; Hastings, N.; Dennis, P.; Kelley-Loughnane, N.; Berry, R. J.
10.1101/2023.07.29.551023 — biophysics — Posted on 2023-07-30
203 A multiplex, prime editing framework for identifying drug resistance variants at scale
Chardon, F. M.; Suiter, C.; Daza, R.; Smith, N. T.; Parrish, P.; McDiarmid, T.; Lalanne, J.-B.; Martin, B. K.; Calderon, D.; Ellison, A.; Berger, A.; Shendure, J.; Starita, L. M.
10.1101/2023.07.27.550902 — genomics — Posted on 2023-07-30
205 Analysis of human BBS protein homologues in insects support alternative non-ciliary functions
Ewerling, A.; Graebling, I.; Wierczeiko, A.; Kotzurek, E.; Foitzik, S.; Gerber, S.; Colgan, T.; May-Simera, H. L.
10.1101/2023.07.28.550953 — evolutionary biology — Posted on 2023-07-30
206 Ploidy-specific transcriptomes shed light on the heterogeneous identity and metabolism of developing pericarp cells
Tourdot, E.; Maza, E.; Djari, A.; Martin, P. G.; Gevaudant, F.; Chevalier, C.; Pirrello, J.; Gonzalez, N.
10.1101/2023.07.28.550816 — plant biology — Posted on 2023-07-30
211 The shared ancestry between the C9orf72 hexanucleotide repeat expansion and intermediate-length alleles using haplotype sharing trees and HAPTK
Rautila, O. S.; Kaivola, K.; Rautila, H.; Hokkanen, L.; Launes, J.; Strandberg, T. E.; Laaksovirta, H.; Palmio, J.; Tienari, P. J.
10.1101/2023.07.28.550820 — genetics — Posted on 2023-07-30
212 Evolutionary signatures of human cancers revealed via genomic analysis of over 35,000 patients
Fontana, D.; Crespiatico, I.; Crippa, V.; Malighetti, F.; Villa, M.; Angaroni, F.; De Sano, L.; Aroldi, A.; Antoniotti, M.; Caravagna, G.; Piazza, R.; Graudenzi, A.; Mologni, L.; Ramazzotti, D.
10.1101/2023.07.27.550506 — genetics — Posted on 2023-07-30
213 Multiplexed functional assessments of MYH7 variants in human cardiomyocytes at scale
Friedman, C. E.; Fayer, S.; Pendyala, S.; Chien, W.-M.; Tran, L.; Chao, L. S.; McKinstry, A.; Ahmed, D.; Loiben, A.; Farris, S. D.; Stempien-Otero, A.; Jonlin, E.; Murry, C. E.; Starita, L. M.; Fowler, D. M.; Yang, K.-C.
10.1101/2023.07.28.551073 — genetics — Posted on 2023-07-30
214 Dynamic simulations of feeding and respiration of the early Cambrian periderm-bearing cnidarian polyps
Zhang, Y.; Wang, X.; Han, J.; Xiao, J.; Yong, Y.; Yu, C.; Yue, N.; Sun, J.; He, K.; Hao, W.; Zhang, T.; Wang, D.; Yang, X.
10.1101/2023.07.28.550931 — evolutionary biology — Posted on 2023-07-30
215 Mining threats in high-level biodiversity conservation policies
Torres, A.; zu Ermgassen, S. O. S. E.; Navarro, L. M.; Ferri-Yanez, F.; Teixeira, F. Z.; Wittkopp, C.; Rosa, I. M. D.; Liu, J.
10.1101/2023.07.30.550308 — ecology — Posted on 2023-07-30
216 Predictive microbial community changes across a temperature gradient
Sun, X.; Folmar, J.; Favier, A.; Pyenson, N.; Sanchez, A.; Rebolleda-Gomez, M.
10.1101/2023.07.28.550899 — ecology — Posted on 2023-07-30
218 Functional traits fail to predict long-term responses to climate change
Ash, J. D.; Li, D.; Johnson, S. E.; Rogers, D. A.; Waller, D. M.
10.1101/2023.07.27.550868 — ecology — Posted on 2023-07-30
221 Nextflow Pipeline for Visium and H&E Data from Patient-Derived Xenograft Samples
Domanskyi, S.; Srivastava, A.; Kaster, J.; Li, H.; Herlyn, M.; Rubinstein, J. C.; Chuang, J. H.
10.1101/2023.07.27.550727 — bioinformatics — Posted on 2023-07-30
225 Machine learning assisted health viability assay for mouse embryos with artificial confocal microscopy (ACM)
Goswami, N.; Winston, N.; Choi, W.; Lai, N. Z. E.; Arcanjo, R. B.; Chen, X.; Sobh, N.; Nowak, R. A.; Anastasio, M. A.; Popescu, G.
10.1101/2023.07.30.550591 — bioengineering — Posted on 2023-07-30
230 Widespread deviant patterns of heterozygosity in whole-genome sequencing due to autopolyploidy, repeated elements and duplication
Dallaire, X.; Bouchard, R.; Henault, P.; Diaz, G. U.; Normandeau, E.; Merot, C.; Bernatchez, L.; Moore, J.-S.
10.1101/2023.07.27.550877 — genomics — Posted on 2023-07-30
231 Quantifying visual acuity in Heliconius butterflies
Wright, D. S.; Manel, A. N.; Guachamin-Rosero, M.; Chamba-Vaca, P.; Bacquet, C. N.; Merrill, R. M.
10.1101/2023.07.10.548283 — evolutionary biology — Posted on 2023-07-30
238 Dimension reduction of microbiome data linked Bifidobacterium to allergic rhinitis
Komaki, S.; Sahoyama, Y.; Hachiya, T.; Koseki, K.; Ogata, Y.; Hamazato, F.; Shiozawa, M.; Nakagawa, T.; Suda, W.; Hattori, M.; Kawakami, E.
10.1101/2023.07.18.548236 — microbiology — Posted on 2023-07-30
239 Disease diagnostics using machine learning of immune receptors
Zaslavsky, M. E.; Craig, E.; Michuda, J. K.; Ram-Mohan, N.; Lee, J.-Y.; Nguyen, K. D.; Hoh, R. A.; Pham, T. D.; Parsons, E. S.; Macwana, S. R.; DeJager, W.; Roskin, K. M.; Cunningham-Rundles, C.; Moody, M. A.; Haynes, B. F.; Goldman, J. D.; Heath, J. R.; Balboni, I.; Utz, P. J.; Nadeau, K. C.; Pinsky, B. A.; Blish, C. A.; Merrill, J. T.; Guthridge, J. M.; James, J. A.; Yang, S.; Tibshirani, R.; Kundaje, A.; Boyd, S. D.
10.1101/2022.04.26.489314 — immunology — Posted on 2023-07-30
240 Fine tuning of CpG spatial distribution with DNA origami for improved therapeutic cancer vaccination
Zeng, Y. C.; Young, O. J.; Wintersinger, C. M.; Anastassacos, F. M.; MacDonald, J. I.; Isinelli, G.; Dellacherie, M. O.; Sobral, M.; Bai, H.; Graveline, A.; Vernet, A.; Sanchez-Ventura, M.; Mulligan, K.; Choi, Y.-J.; Ferrante, T. C.; Keskin, D.; Fell, G.; Neuberg, D.; Wu, C.; Mooney, D.; Kwon, I.-C.; Ryu, J.-H.; Shih, W.
10.1101/2022.06.08.495340 — synthetic biology — Posted on 2023-07-30
243 Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
Mavrommatis, L.; Jeong, H.-W.; Kindler, U.; Gomez-Giro, G.; Kienitz, M.-C.; Stehling, M.; Psathaki, O. E.; Zeuschner, D.; Bixel, G.; Han, D.; Morosan-Puopolo, G.; Gerovska, D.; Yang, J. H.; Kim, J. B.; Arauzo-Bravo, M. J.; Schwamborn, J. C.; Hahn, S. A.; Adams, R. H.; Scholer, H. R.; Vorgerd, M.; Brand-Saberi, B.; Zaehres, H.
10.1101/2020.09.14.295832 — bioengineering — Posted on 2023-07-30
244 Sperm traits of the three genetic morphs in the ruff sandpiper
Bulla, M.; Küpper, C.; Lank, D. B.; Albrechtova, J.; Loveland, J. L.; Martin, K.; Teltscher, K.; Cragnolini, M.; Lierz, M.; Albrecht, T.; Forstmeier, W.; Kempenaers, B.
10.1101/2023.07.27.550846 — evolutionary biology — Posted on 2023-07-30
246 Actin-Driven Nanotopography Enhances Integrin Molecular Clutch in Developing Tissue
Chen, T.; Huertas Fernandez-Espartero, C.; Illand, A.; Tsai, C.-T.; Yang, Y.; Klapholz, B.; Jouchet, P.; Fabre, M.; Rossier, O.; Cui, B.; Leveque-Fort, S.; Brown, N. H.; Giannone, G.
10.1101/2023.07.28.550203 — cell biology — Posted on 2023-07-30
247 Surface crosslinking of virus-like particles increases resistance to proteases, low pH and mechanical stress for mucosal applications
Ali, A.; Ganguillet, S.; Turgay, Y.; Keys, T.; Causa, E.; Fradique, R.; Lutz-Bueno, V.; Chesnov, S.; Lin, C.-W.; Lentsch, V.; Kotar, J.; Cicuta, P.; Mezzenga, R.; Slack, E.; Radiom, M.
10.1101/2023.07.29.550271 — biophysics — Posted on 2023-07-30
249 An interbacterial lipase toxin with an unprecedented reverse domain arrangement defines a new class of type VII secretion system effector
Garrett, S. R.; Mietrach, N.; Deme, J.; Bitzer, A.; Yang, Y.; Ulhuq, F. R.; Kretschmer, D.; Heilbronner, S.; Smith, T. K.; Lea, S. M.; Palmer, T.
10.1101/2023.07.29.551094 — microbiology — Posted on 2023-07-29
250 Metabolic arms race between a plant and a fungal pathogen
Liu, Y.; Mahdi, L.; Porzel, A.; Stark, P.; Esposto, D.; Scherr-Henning, A.; Bathe, U.; Acosta, I. F.; Zuccaro, A.; Balcke, G. U.; Tissier, A. F.
10.1101/2023.07.29.551000 — plant biology — Posted on 2023-07-29
251 mAFiA: Detecting m6A at single-molecular resolution via direct-RNA sequencing
Chan, A.; Naarmann-de Vries, I.; Scheitl, C.; Hoebartner, C.; Dieterich, C.
10.1101/2023.07.28.550944 — bioinformatics — Posted on 2023-07-29
252 Topoisomerase IIα C-terminal Domain Mutations and Catalytic Function
Musselman, J. R.; England, D. C.; Fielding, L. A.; Durham, C. T.; Baxter, E.; Jiang, X.; Lisic, E. C.; Deweese, J. E.
10.1101/2023.07.29.551120 — biochemistry — Posted on 2023-07-29
253 A Non-Coding Variant in SLC15A4 Drives Lysosomal Deacidification and Lupus Susceptibility
Maiti, G. P.; Singh, M. K.; Reddy-Rallabandi, H.; Fazel-Najafabadi, M.; Looger, L.; Nath, S. K.
10.1101/2023.07.28.551056 — genetics — Posted on 2023-07-29
258 Global Pannexin 1-deletion increases tumor-infiltrating lymphocytes in the BRAF/Pten mouse melanoma model.
Sanchez-Pupo, R. E.; Finch, G.; Johnston, D. E.; Craig, H.; Abdo, R.; Barr, K. J.; Kerfoot, S. M.; Dagnino, L.; Penuela, S.
10.1101/2023.07.28.551021 — cancer biology — Posted on 2023-07-29
263 Structure and function of a YeeE-YeeD complex for sophisticated thiosulfate uptake
Ikei, M.; Miyazaki, R.; Monden, K.; Naito, Y.; Takeuchi, A.; Takahashi, Y. S.; Tanaka, Y.; Mori, T.; Ichikawa, M.; Tsukazaki, T.
10.1101/2023.07.28.550924 — biochemistry — Posted on 2023-07-29
265 An adaptive biomolecular condensation response is conserved across environmentally divergent species
Keyport Kik, S.; Christopher, D.; Glauninger, H.; Wong Hickernell, C.; Bard, J. A. M.; Ford, M.; Sosnick, T. R.; Drummond, D. A.
10.1101/2023.07.28.551061 — cell biology — Posted on 2023-07-29
266 Virus-derived circular RNAs populate hepatitis C virus-infected cells
Cao, Q.; Boonchuen, P.; Chen, T.-C.; Lei, S.; Somboonwiwat, K.; Sarnow, P.
10.1101/2023.07.28.551052 — microbiology — Posted on 2023-07-29
267 Effect of a topically applied gel containing antibodies from bovine milk on the relative abundance of Staphylococci in the canine skin microbiome
Klaassens, E. S.; Auxilia, S.; Baak, M. L.; Bongoni, R.; van Damme, C. M. M.; Bijker, S.; Dietz, N.; Winter, E.; Broere, F.; Foerster, B.
10.1101/2023.07.29.551104 — microbiology — Posted on 2023-07-29
274 Adapting antibacterial display to identify serum active macrocyclic peptide antibiotics
Randall, J. R.; Groover, K.; O'Donnell, A.; Garza, J.; Cole, T. J.; Davies, B.
10.1101/2023.07.28.550711 — microbiology — Posted on 2023-07-29
276 Chronic brain functional ultrasound imaging in freely moving rodents performing cognitive tasks
El Hady, A.; Takahashi, D. Y.; Sun, R.; Akinwale, O.; Boyd-Meredith, T.; Zhang, Y.; Charles, A.; Brody, C.
10.1101/2022.01.29.478327 — neuroscience — Posted on 2023-07-29
282 Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions
Edwards, F.; Fantozzi, G.; Simon, A. Y.; Morretton, J.-P.; Herbette, A.; Tijhuis, A. E.; Wardenaar, R.; Foulane, S.; Gemble, S.; Spierings, D. C. J.; Foijer, F.; Mariani, O.; Vincent-Salomon, A.; Roman-Roman, S.; Sastre-Garau, X.; Goundiam, O.; Basto, R.
10.1101/2023.07.28.550973 — cell biology — Posted on 2023-07-29
283 Epigenetic modifications driving ground state pluripotency exit require an NF-κB-independent chromatin IκBα function
Galan, L.; Alvarez-Villanueva, D.; Maqueda, M.; Barrero, M.; IGLESIAS, A.; Bertran, j.; ALVAREZ, D.; GARCIA-PRIETO, C.; BALLARE, C.; RODRIGUEZ-CORTEZ, V.; BUENO, C.; VIDAL, A.; Villanueva, A.; Menendez, P.; Di Croce, L.; Payer, B.; Esteller, M.; Espinosa, L.; Bigas, A.
10.1101/2023.07.28.550934 — cell biology — Posted on 2023-07-29
284 Distinct human stem cell subpopulations drive adipogenesis and fibrosis in musculoskeletal injury
Garcia, S. M.; Diaz, A.; Lau, J.; Chi, H. M.; Lizarraga, M.; Davies, M. R.; Liu, X.; Feeley, B. T.
10.1101/2023.07.28.551038 — cell biology — Posted on 2023-07-29
285 Epidermal IL-33 drives inflammation in necroptosis-induced skin inflammation by recruiting TNF-producing immune cells.
Fernandez-Nasarre, A.; Srivastava, V.; Bennett, F.; Michel, L.; Bensussan, A.; Choy, E. H.; Bagot, M.; Bonnet, M. C.
10.1101/2023.07.28.550963 — immunology — Posted on 2023-07-29
291 Unbiased method for spectral analysis of cells with great diversity of autofluorescence spectra
Roet, J. E. G.; Mikula, A. M.; de Kok, M.; Chadick, C. H.; Garcia Vallejo, J. J.; Roest, H. P.; van der Laan, L. J. W.; de Winde, C. M.; Mebius, R. E.
10.1101/2023.07.28.550943 — cell biology — Posted on 2023-07-29
295 Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles
Santiago, J. V.; Natu, A.; Ramelow, C. C.; Rayaprolu, S.; Xiao, H.; Kumar, V.; Seyfried, N.; Rangaraju, S.
10.1101/2023.07.28.551012 — neuroscience — Posted on 2023-07-29
296 Sex, gender diversity, and brain structure in children ages 9 to 11 years old
Torgerson, C.; Ahmadi, H.; Choupan, J.; Fan, C. C.; Blosnich, J. R.; Herting, M.
10.1101/2023.07.28.551036 — neuroscience — Posted on 2023-07-29
297 Perceptions on the genetic biocontrol of invasive carp
Erickson, S. E.; Lhewa, P.; Rundquist, K.; Schultz, S.; Levers, L.; Smanski, M.
10.1101/2023.07.27.550879 — scientific communication and education — Posted on 2023-07-29
298 Inhibition of YAP the MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers
Jessen, M.; Gertzmann, D.; Liss, F.; Zenk, F.; Baehner, L.; Schoeffler, V.; Ade, C. P.; von Eyss, B.; Gaubatz, S.
10.1101/2023.07.27.550917 — cancer biology — Posted on 2023-07-29
299 KoNA: Korean Nucleotide Archive as a New Data Repository for Nucleotide Sequence Data
Ko, G.; Lee, J.; Sim, Y. M.; Song, W.; Yoon, B.-H.; Byeon, I.; Lee, B. H.; Kim, S.-O.; Choi, J.; Jang, I.; Kim, H.; Yang, J. O.; Jang, K.; Kim, S.; Kim, J.-H.; Jeon, J.; Jung, J.; Hwang, S.; Park, J.-H.; Kim, P.-G.; Kim, S.-Y.; Lee, B.
10.1101/2023.07.27.550450 — genomics — Posted on 2023-07-29
306 A disinhibitory circuit mechanism explains a general principle of peak performance during mid-level arousal
Beerendonk, L.; Mejias, J. F.; Nuiten, S. A.; de Gee, J. W.; Fahrenfort, J. J.; van Gaal, S.
10.1101/2023.07.28.550956 — neuroscience — Posted on 2023-07-29
308 Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture
Glass, M. R.; Waxman, E. A.; Yamashita, S.; Lafferty, M.; Beltran, A.; Farah, T.; Patel, N. K.; Matoba, N.; Ahmed, S.; Srivastava, M.; Drake, E.; Davis, L. T.; Yeturi, M.; Sun, K.; Love, M. I.; Hashimoto-Torii, K.; French, D. L.; Stein, J. L.
10.1101/2023.07.28.550873 — neuroscience — Posted on 2023-07-29
309 A genetic screen to uncover molecular mechanisms underlying lipid transfer protein function at membrane contact sites and neurodegeneration.
Mishra, S.; Manohar, V.; Chandel, S.; Manoj, T.; Bhattacharya, S.; Hegde, N.; Nath, V. R.; Hegde, N.; Wendling, C.; Di Mattia, T.; Martinet, A.; Chimata, P.; Alpy, F.; PADINJAT, R.
10.1101/2023.07.28.550979 — neuroscience — Posted on 2023-07-29
310 Genome scale metabolic network modelling for metabolic profile predictions
Cooke, J.; Delmas, M.; Wieder, C.; Rodriguez-Mier, P.; Frainay, C.; Vinson, F.; Ebbels, T.; Poupin, N.; Jourdan, F.
10.1101/2023.07.26.550622 — systems biology — Posted on 2023-07-29
314 Functional and anatomical connectivity predict brain stimulation's mnemonic effects
Ezzyat, Y.; Kragel, J. E.; Solomon, E. A.; Lega, B. C.; Aronson, J. P.; Jobst, B. C.; Gross, R. E.; Sperling, M. R.; Worrell, G. A.; Sheth, S. A.; Wanda, P. A.; Rizzuto, D. S.; Kahana, M. J.
10.1101/2023.07.27.550851 — neuroscience — Posted on 2023-07-29
316 Network Statistics of the Whole-Brain Connectome of Drosophila
Lin, A.; Yang, R.; Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. E.; Costa, M.; Eichler, K.; Bates, A. S.; Eckstein, N.; Funke, J.; Jefferis, G. S. X. E.; Murthy, M.
10.1101/2023.07.29.551086 — neuroscience — Posted on 2023-07-29
321 Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM
Bashore, F. M.; Katis, V. L.; Du, Y.; Sikdar, A.; Wang, D.; Bradshaw, W. J.; Rygiel, K. A.; Leisner, T. M.; Chalk, R.; Mishra, S.; Williams, A. C.; Gileadi, O.; Brennan, P. E.; Wiley, J. C.; Gockley, J.; Cary, G. A.; Carter, G. W.; Young, J. E.; Pearce, K. H.; Fu, H.; the Emory-Sage-SGC TREAT-AD Center, ; Axtman, A. D.
10.1101/2023.07.28.551026 — neuroscience — Posted on 2023-07-29
328 Spatial profiling of ovarian clear cell carcinoma reveals immune-hot features
Tai, Y.-T.; Lin, W.-C.; Wang, D. Y.-T.; Ye, J.; Tan, T. Z.; Wei, L.-H.; Huang, R. Y.-J.
10.1101/2023.07.27.550775 — cancer biology — Posted on 2023-07-29
333 Deep Batch Active Learning for Drug Discovery
Bailey, M.; Moayedpour, S.; Li, R.; Corrochano-Navarro, A.; Kötter, A.; Kogler-Anele, L.; Riahi, S.; Grebner, C.; Hessler, G.; Matter, H.; Bianciotto, M.; Mas, P.; Bar-Joseph, Z.; Jager, S.
10.1101/2023.07.26.550653 — bioinformatics — Posted on 2023-07-29
335 GAPiM: Discovering Genetic Variations on a Real Processing-in-Memory System
Abecassis, N.; Gomez Luna, J.; Mutlu, O.; Ginosar, R.; Moisson-Franckhauser, A.; Yavits, L.
10.1101/2023.07.26.550623 — bioinformatics — Posted on 2023-07-29
338 Eyes on nature: Embedded vision cameras for multidisciplinary biodiversity monitoring
Darras, K. F. A.; Balle, M.; Xu, W.; Yan, Y.; Zakka, V. G.; Toledo-Hernandez, M.; Sheng, D.; Lin, W.; Zhang, B.; Lan, Z.; Fupeng, L.; Wanger, T. C.
10.1101/2023.07.26.550656 — ecology — Posted on 2023-07-29
339 Chronic BCR signaling generates and maintains age-associated B cells from anergic B cells
Imabayashi, K.; Yada, Y.; Ushijima, M.; Yoshimura, M.; Iwasaki, T.; Akashi, K.; Niiro, H.; Baba, Y.
10.1101/2023.07.26.550463 — immunology — Posted on 2023-07-29
342 Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
Howard, G. C.; Wang, J.; Rose, K. L.; Patel, P.; Tsui, T.; Florian, A. C.; Lorey, S. L.; Grieb, B. C.; Smith, B. N.; Slota, M. J.; Reynolds, E. M.; Goswami, S.; Savona, M. R.; Lee, T.; Fesik, S. W.; Liu, Q.; Tansey, W. P.
10.1101/2023.07.26.550648 — cancer biology — Posted on 2023-07-29
344 ProteoMixture: A Cell Type Deconvolution Tool for Bulk Tissue Proteomics Data
Teng, P.-n.; Schaaf, J. P.; Abulez, T.; Hood, B. L.; Wilson, K. N.; Litzi, T. J.; Conrads, K. A.; Hunt, A. L.; Olowu, V.; Oliver, J.; Park, F. S.; Edwards, M.; Chiang, A.; Raj-Kumar, P.-K.; Tarney, C. M.; Darcy, K. M.; Phippen, N. T.; Maxwell, G. L.; Conrads, T. P.; Bateman, N. W.
10.1101/2023.07.27.550810 — bioinformatics — Posted on 2023-07-29
347 Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies
Shi, P.; Martino, C.; Han, R.; Janssen, S.; Buck, G.; Serrano, M.; Owzar, K.; Knight, R.; Shenhav, L.; Zhang, A. R.
10.1101/2023.07.26.550749 — bioinformatics — Posted on 2023-07-29
350 Soft robotics-enabled large animal model of HFpEF hemodynamics for device testing
Rosalia, L.; Ozturk, C.; Wang, S.; Quevedo, D.; Saeed, M.; Mauskapf, A.; Roche, E.
10.1101/2023.07.26.550654 — bioengineering — Posted on 2023-07-29
352 In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene
De Giorgi, M.; Park, S. H.; Castoreno, A.; Cao, M.; Hurley, A.; Saxena, L.; Chuecos, M. A.; Walkey, C. J.; Doerfler, A. M.; Furgurson, M. N.; Ljungberg, C.; Patel, K. R.; Hyde, S.; Chickering, T.; Lefebvre, S.; Wassarman, K.; Miller, P.; Qin, J.; Schlegel, M. K.; Zlatev, I.; Li, R. G.; Kim, J.; Martin, J. F.; Bissig, K.-D.; Jadhav, V.; Bao, G.; Lagor, W. R.
10.1101/2023.07.26.550728 — genetics — Posted on 2023-07-29
356 Arabidopsis thaliana subclass I ACTIN DEPOLYMERIZING FACTORs regulate nuclear organization and gene expression
Matsumoto, T.; Higaki, T.; Takatsuka, H.; Kutsuna, N.; Ogata, Y.; Hasezawa, S.; Umeda, M.; Inada, N.
10.1101/2023.04.19.537409 — cell biology — Posted on 2023-07-29
357 A Spatiotemporal Proteomic Map of Human Adipogenesis
Klingelhuber, F.; Frendo-Cumbo, S.; Hmeadi, O.; Taylor, A. J.; Kakimoto, P.; Ribicic, S.; Couchet, M.; Wabitsch, M.; Iuso, A.; Messias, A. C.; Mueller, T. D.; Ryden, M.; Mejhert, N.; Krahmer, N.
10.1101/2023.07.01.547321 — molecular biology — Posted on 2023-07-29
359 Serpine1 negatively regulates Th1 cell responses in experimental autoimmune encephalomyelitis.
Akbar, I.; Tang, R.; Baillargeon, J.; Roy, A.-P.; Doss, P. M. I. A.; Zhu, C.; Kuchroo, V. K.; Rangachari, M.
10.1101/2023.07.13.548887 — immunology — Posted on 2023-07-29
360 The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation
Wheeler, B. D.; Gagnon, J. D.; Zhu, W. S.; Munoz-Sandoval, P.; Wong, S. K.; Simeonov, D. S.; Li, Z.; Debarge, R.; Spitzer, M.; Marson, A.; Ansel, K. M.
10.1101/2023.04.14.536843 — immunology — Posted on 2023-07-29
361 Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus
Wilmot, J. H.; Diniz, C. R. A. F.; Crestani, A. P.; Puhger, K.; Roshgadol, J.; Tian, L.; Wiltgen, B. J.
10.1101/2022.10.17.512590 — neuroscience — Posted on 2023-07-29
362 Hippocampal damage causes retrograde amnesia for objects' visual, but not odour, properties in male rats
Lacoursiere, S. G.; McAllister, B. B.; Hadikin, C.; Tschetter, W. W.; Lehmann, H.; Sutherland, R. J.
10.1101/2022.09.14.508050 — neuroscience — Posted on 2023-07-29
363 What does the mean mean? A simple test for neuroscience.
Tlaie, A.; Shapcott, K. A.; van der Plas, T.; Rowland, J. M.; Lees, R.; Keeling, J.; Packer, A.; Tiesinga, P.; Schölvinck, M.; Havenith, M. N.
10.1101/2021.11.28.469673 — neuroscience — Posted on 2023-07-29
364 Modeling and Simulation of Rat Non-Barrel Somatosensory Cortex. Part I: Modeling Anatomy
Reimann, M. W.; Bolanos Puchet, S.; Egas Santander, D.; Courcol, J.-D.; Arnaudon, A.; Coste, B.; Delemontex, T.; Devresse, A.; Dictus, H.; Dietz, A.; Ecker, A.; Favreau, C.; Ficarelli, G.; Gevaert, M.; Hernando, J. B.; Herttuainen, J.; Isbister, J. B.; Kanari, L.; Keller, D.; King, J. G.; Kumbhar, P.; Lapere, S.; Lazovskis, J.; Lu, H.; Ninin, N.; Pereira, F.; Planas, J.; Pokorny, C.; Riquelme, J. L.; Romani, A.; Shi, Y.; Smith, J. P.; Sood, V.; Srivastava, M.; Van Geit, W.; Vanherpe, L.; Wolf, M.; Levi, R.; Hess, K.; Schürmann, F.; Muller, E. B.; Ramaswamy, S.; Markram, H.
10.1101/2022.08.11.503144 — neuroscience — Posted on 2023-07-29
365 Species -Shared and -Unique Gyral Peaks on Human and Macaque Brains
Zhang, S.; Zhang, T.; Cao, G.; Zhou, J.; He, Z.; Li, X.; Ren, Y.; Jiang, X.; Guo, L.; Han, J.; Liu, T.
10.1101/2023.07.26.550760 — neuroscience — Posted on 2023-07-29
367 A peptide that regulates metalation and function of the Arabidopsis ethylene receptor.
Mudge, A. M.; Mehdi, S.; Michaels, W. E.; Oroza-Puente, B.; Shen, W.; Sadanandom, A.; Hetherington, F. M.; Hoppen, C.; Uzun, B.; Groth, G.; Topping, J. F.; Robinson, N. J.; Lindsey, K.
10.1101/2023.06.15.545071 — plant biology — Posted on 2023-07-29
368 Sustained Delivery of GLP-1 Receptor Agonists from Injectable Biomimetic Hydrogels Improves Treatment of Diabetes
d'Aquino, A. I.; Maikawa, C. L.; Nguyen, L. T.; Lu, K.; Hall, I. A.; Jons, C. K.; Kasse, C. I.; Yan, J.; Prossnitz, A. N.; Chang, E.; Baker, S. W.; Hovgaard, L.; Steensgaard, D. B.; Andersen, H. B.; Simonsen, L.; Appel, E. A.
10.1101/2023.01.28.526057 — bioengineering — Posted on 2023-07-29
369 α-carboxysome size is controlled by the disordered scaffold protein CsoS2
Oltrogge, L. M.; Chen, A. W.; Chaijarasphong, T.; Turnsek, J. B.; Savage, D. F.
10.1101/2023.07.07.548173 — biochemistry — Posted on 2023-07-29
373 Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model
Lee, M.-S.; Sivapatham, A.; Leiferman, E. M.; Jiao, H.; Lu, Y.; Nemke, B. W.; Leiferman, M.; Markel, M. D.; Li, W.-J.
10.1101/2023.07.25.550409 — bioengineering — Posted on 2023-07-29
375 Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe
Ouasti, F.; Audin, M.; Freon, K.; Quivy, J.-P.; Tachekort, M.; Cesard, E.; Thureau, A.; Ropars, V.; Varela, P. F.; Moal, G.; Soumana-Amadou, I.; Uryga, A.; Legrand, P.; Andreani, J.; Guerois, R.; Almouzni, G.; Lambert, S. A.; Ochsenbein, F.
10.1101/2023.06.02.543505 — biochemistry — Posted on 2023-07-29
382 Hallucination proneness alters sensory feedback processing in self-voice production
Duggirala, S. X.; Schwartze, M.; Goller, L. K.; Linden, D. E. J.; Pinheiro, A.; Kotz, S. A.
10.1101/2023.07.28.550971 — neuroscience — Posted on 2023-07-29
385 Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Kandola, T.; Venkatesan, S.; Zhang, J.; Lerbakken, B. T.; Von Schulze, A.; Blanck, J. F.; Wu, J.; Unruh, J. R.; Berry, P.; Lange, J. J.; Box, A. C.; Cook, M.; Sagui, C.; Halfmann, R.
10.1101/2023.03.20.533418 — biophysics — Posted on 2023-07-29
387 DeepMap: A deep learning-based model with four-line code for prediction-based breeding in crops
Kumar, A.; Sundaram, K. T.; Gnanapragasam, N.; Singh, U. M.; Pranesh, K. J.; Venkateshwarlu, C.; Paul, P. J.; Hussain, W.; Bhosale, S.; Kohli, A.; Miro, B.; Singh, V. K.; Sinha, P.
10.1101/2023.07.26.550275 — genomics — Posted on 2023-07-29
389 A Compact and Effective Photon-Resolved Image Scanning Microscope
Tortarolo, G.; Zunino, A.; Piazza, S.; Donato, M.; Zappone, S.; Pierzynska-Mach, A.; Castello, M.; Vicidomini, G.
10.1101/2023.07.28.549477 — biophysics — Posted on 2023-07-29
392 Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity
Polmear, J.; Hailes, L.; Olshansky, M.; Rischmueller, M.; L'Estrange-Stranieri, E.; Fletcher, A.; Hibbs, M.; Bryant, V.; Good-Jacobson, K.
10.1101/2023.07.27.550912 — immunology — Posted on 2023-07-29
394 The Phage-shock-protein (PSP) Envelope Stress Response:Discovery of Novel Partners and Evolutionary History
Ravi, J.; Anantharaman, V.; Chen, S. Z.; Brenner, E. P.; Datta, P.; Aravind, L.; Gennaro, M. L.
10.1101/2020.09.24.301986 — bioinformatics — Posted on 2023-07-29
395 Targeted protein editing with an antibody-based system
Rimon, O.; Konc, J.; Roy Chowdhury, V.; Bernardes, G. J. L.; Vendruscolo, M.
10.1101/2023.07.28.551006 — biochemistry — Posted on 2023-07-29
400 Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells
Gao, K. M.; Nundel, K.; Chiang, K.; Yin, X.; Utz, P. J.; Fitzgerald, K. A.; Marshak-Rothstein, A.
10.1101/2023.07.28.551002 — immunology — Posted on 2023-07-28
401 FiPhA: An Open-Source Platform for Fiber Photometry Analysis
Bridge, M. F.; Wilson, L. R.; Panda, S.; Stevanovic, K. D.; Letsinger, A. C.; McBride, S. J.; Cushman, J. D.
10.1101/2023.07.21.550098 — neuroscience — Posted on 2023-07-28
405 Default Values And Read-Across Proposal For Dermal Absorption Based On Human Skin In Vitro Studies Dataset With Pesticides
Sarti, D. A.; Wagner, J.; Palma, F.; Kalvan, H.; Giachini, M. F.; Lautenschalaeger, D.; Lupianhez, V.; Pires, J. C.; Sales, M.; de Faria, P. M.; Bertomeu, L. C.; Le Bras, M.
10.1101/2023.05.11.540395 — pharmacology and toxicology — Posted on 2023-07-28
408 Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
Prithiviraj, S.; Linderfalk, K.; Ferveur, S.; Garcia Garcia, A.; Gil, D. H.; Falck, L. N.; Subramaniam, A.; Bourgine, P. E.
10.1101/2023.07.28.550935 — bioengineering — Posted on 2023-07-28
412 Genetic and functional diversity of beta-N-acetylgalactosamine residue-targeting glycosidases expanded by deep-sea metagenome
Sumida, T.; Hiraoka, S.; Usui, K.; Ishiwata, A.; Sengoku, T.; Stubbs, K. A.; Tanaka, K.; Deguchi, S.; Fushinobu, S.; Nunoura, T.
10.1101/2023.07.28.550916 — biochemistry — Posted on 2023-07-28
415 Development of a PNGase Rc column for online deglycosylation of complex glycoproteins during HDX-MS
Lambert, T. O. T.; Gramlich, M.; Stutzke, L. S.; Smith, L.; Deng, D.; Kaiser, P. D.; Rothbauer, U.; Benesch, J. L.; Wagner, C.; Koenig, M.; Pompach, P.; Novak, P.; Zeck, A.; Rand, K. D.
10.1101/2023.07.28.550801 — biochemistry — Posted on 2023-07-28
418 Functional and topological analysis of PSENEN, the fourth subunit of the gamma-secretase complex
Serneels, L.; Bammens, L.; Zwijsen, A.; Tolia, A.; Chavez Gutierrez, L.; De Strooper, B.
10.1101/2023.07.28.550932 — molecular biology — Posted on 2023-07-28
420 Prolonged exposure to lung-derived cytokines is associated with inflammatory activation of microglia in patients with COVID-19
Grant, R. A.; Poor, T. A.; Sichizya, L.; Diaz, E.; Bailey, J. I.; Soni, S.; Senkow, K. J.; Perez-Leonor, X. G.; Abdala-Valencia, H.; Lu, Z.; Donnelly, H. K.; Tighe, R. M.; Lomasney, J. W.; Wunderink, R. G.; Singer, B. D.; Misharin, A. V.; Budinger, G. R. S.; The NU SCRIPT Investigators,
10.1101/2023.07.28.550765 — immunology — Posted on 2023-07-28
423 New design strategies for ultra-specific CRISPR-Cas13a-based RNA-diagnostic tools with single-nucleotide mismatch sensitivity
Molina Vargas, A. M.; Osborn, R. M.; Sinha, S.; Arantes, P. R.; Patel, A.; Dewhurst, S.; Palermo, G.; O'Connell, M. R.
10.1101/2023.07.26.550755 — molecular biology — Posted on 2023-07-28
425 The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis
Wicke, D.; Neumann, P.; Goessringer, M.; Chernev, A.; Poehlein, A.; Daniel, R.; Urlaub, H.; Hartmann, R. K.; Ficner, R.; Stuelke, J.
10.1101/2023.07.28.550789 — microbiology — Posted on 2023-07-28
426 Butyrate Protects against SARS-CoV-2-induced Tissue Damage in Golden Hamsters.
Yu, H.; Yuan, L.; Yan, Z.; Zhou, M.; Ye, J.; Wu, K.; Chen, W.; Chen, R.; Xia, N.-S.; Guan, Y.; Zhu, H.
10.1101/2023.07.27.550811 — microbiology — Posted on 2023-07-28
429 Adapting antibacterial display to identify serum active macrocyclic peptide antibiotics
Randall, J. R.; Groover, K.; O'Donnell, A.; Garza, J.; Cole, T. J.; Davies, B.
10.1101/2023.07.28.550711 — microbiology — Posted on 2023-07-28
432 Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells
Chiariello, A. M.; Abraham, A.; Bianco, S.; Esposito, A.; Vercellone, F.; Conte, M.; Fontana, A.; Nicodemi, M.
10.1101/2023.07.27.550709 — biophysics — Posted on 2023-07-28
437 ChromaFold predicts the 3D contact map from single-cell chromatin accessibility
Gao, V. R.; Yang, R.; Das, A.; Luo, R.; Luo, H.; McNally, D. R.; Karagiannidis, I.; Rivas, M. A.; Wang, Z.-m.; Barisic, D.; Karbalayghareh, A.; Wong, W.; Zhan, Y.; Chin, C. R.; Noble, W. S.; Bilmes, J. A.; Apostolou, E.; Kharas, M.; Beguelin, W.; Viny, A. D.; Huangfu, D.; Rudensky, A.; Melnick, A.; Leslie, C. S.
10.1101/2023.07.27.550836 — bioinformatics — Posted on 2023-07-28
438 LipidSIM: inferring mechanistic lipid biosynthesis perturbations from lipidomics with a flexible, low-parameter, systematic Markov Modeling framework
Liang, C.; Murray, S.; Li, Y.; Lee, R.; Low, A.; Sasaki, S.; Chiang, W.-T.; Lin, W.-J.; Mathews, J.; Barnes, W.; Lewis, N. E.
10.1101/2023.07.26.550768 — bioinformatics — Posted on 2023-07-28
439 Single-cell gene expression prediction from DNA sequence at large contexts
Schwessinger, R.; Deasy, J.; Woodruff, R. T.; Young, S.; Branson, K. M.
10.1101/2023.07.26.550634 — genomics — Posted on 2023-07-28
440 Evidence for ecological tuning of novel anuran biofluorescent signals
Whitcher, C.; Ron, S. R.; Ayala-Varela, F.; Crawford, A.; Herrera-Alva, V.; Castillo-Urbina, E.; Grazziotin, F.; Bowman, R. M.; Lemmon, A. R.; Moriarty Lemmon, E.
10.1101/2023.07.25.550432 — evolutionary biology — Posted on 2023-07-28
442 A REM-active basal ganglia circuit that regulates anxiety
Ba, W.; Nollet, M.; Yu, X.; Wong, S.; Miao, A.; Beckwith, E.; Harding, E. C.; Ma, Y.; Yustos, R.; Vyssotski, A.; Wisden, W. C.; Franks, N. P.
10.1101/2023.07.27.550788 — neuroscience — Posted on 2023-07-28
443 Phenotypic screen-based discovery of a small molecule that can increase adult neurogenesis and improve memory
Davies, J.; Hoerder-suabedissen, A.; Musaelyan, K.; Torroba, M.; Daubney, J.; Untermoser, N.; Carter, T.; Bauer, U.; Walker, R.; Harris, K. S.; Bromhead, L.; Suresh, M.; Fouka, P.; Li, Y.; Davies, S.; Webber, C.; Bannerman, D.; Terstappen, G.; Russell, A.; Szele, F.
10.1101/2023.07.27.550845 — neuroscience — Posted on 2023-07-28
444 Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer 's disease
Jury-Garfe, N.; You, Y.; Martinez, P.; Redding-Ochoa, J.; Karahan, H.; Johnson, T. S.; Zhang, J.; Kim, J.; Troncoso, J. C.; Lasagna-Reeves, C. A.
10.1101/2023.07.27.550884 — neuroscience — Posted on 2023-07-28
450 Noribogaine effects on wakefulness and sleep
Castro-Nin, J. P.; serantes, d.; Rodriguez, P.; Gonzalez, B.; Carrera, I.; Torterolo, P.; Gonzalez, J.
10.1101/2023.07.26.550725 — neuroscience — Posted on 2023-07-28
452 Impaired value-based decision-making in Parkinson's Disease Apathy
Gilmour, W.; Mackenzie, G.; Feile, M.; Tayler-Grint, L.; Suveges, S.; Macfarlane, J.; Macleod, A. D.; Marshall, V.; Grunwald, I. Q.; Steele, D.; Gilbertson, T.
10.1101/2023.07.27.550708 — neuroscience — Posted on 2023-07-28
455 Artificial Intelligence Enables the Label-Free Identification of Chronic Myeloid Leukemia Cells with Mitochondrial Morphological Alterations
Suzuki, K.; Watanabe, N.; Torii, S.; Arakawa, S.; Ochi, K.; Tsuchiya, S.; Yamada, K.; Kawamura, Y.; Ota, S.; Komatsu, N.; Shimizu, S.; Ando, M.; Takaku, T.
10.1101/2023.07.26.550632 — cancer biology — Posted on 2023-07-28
456 Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy
Rawat, V.; DeLear, P.; Prashanth, P.; Ozgurses, M. E.; Tebeje, A.; Burns, P. A.; Conger, K. O.; Solis, C.; Hasnain, Y.; Novikova, A.; Endress, J. E.; Gonzalez-Sanchez, P.; Dong, W.; Stephanopoulos, G.; DeNicola, G. M.; Harris, I. S.; Sept, D. S.; Mason, F. M.; Coloff, J. L.
10.1101/2023.07.26.550731 — cancer biology — Posted on 2023-07-28
459 Quantification of circulating tumor DNA using deep learning
Jacobsen Skanderup, A.; Zhu, G.; Rahman, C.; Getty, V.; Baruah, P.; Carrie, H.; Lim, A.; Guo, Y. A.; Poh, Z.; Sim, N.; Abdelmoneim, A.; Cai, Y.; Ho, D.; Thangaraju, S.; Poon, P.; Lau, Y.; Gan, A.; Ng, S.; Odinokov, D.; Koo, S.-L.; Chong, D.; Tay, B.; Tan, T.; Yap, Y.; Chok, A.; Ng, M.; Tan, P.; Tan, D.; Wong, L.; Wong, P.; Tan, I.
10.1101/2023.07.28.550922 — bioinformatics — Posted on 2023-07-28
462 Improved chromosome-level genome assembly for marigold (Tagetes erecta)
Jiang, F.; Yuan, L.; Wang, S.; Wang, H.; Xu, D.; Wang, A.; Fan, W.
10.1101/2023.07.25.550479 — genomics — Posted on 2023-07-28
463 The relationships between genetic ancestry, somatic mutation frequency, and histologic subtypes in high-grade endometrial cancer
Bremseth-Vining, R.; Borda, V.; Craig, D.; Ruterbusch, J. J.; Boerner, J.; Fucinari, J.; Ali-Fehmi, R.; Elshaikh, M.; Abdallah, H.; Maxwell, G. L.; Darcy, K. M.; Dyson, G.; Conrads, T.; Bateman, N.; Cote, M.; O'Connor, T. D.
10.1101/2023.07.26.550722 — genomics — Posted on 2023-07-28
464 Century-old chromatin architecture preserved with formaldehyde
Hahn, E. E.; Stiller, J.; Alexander, M. R.; Grealy, A.; Taylor, J. M.; Jackson, N.; Frere, C. H.; Holleley, C. E.
10.1101/2023.07.26.550239 — genomics — Posted on 2023-07-28
466 Understanding the Immunomodulatory Effects of Bovine Colostrum: Insights into IL-6/IL-10 Axis-Mediated Inflammatory Control
Grigaleviciute, R.; Matusevicius, P.; Planciuniene, R.; Stankevicius, R.; Radzeviciute-Valciuke, E.; Baleviciute, A.; Zinkeviciene, A.; Zigmantaite, V.; Kucinskas, A.; Kavaliauskas, P.
10.1101/2023.07.26.550707 — immunology — Posted on 2023-07-28
468 Visual feature tuning properties of stimulus-driven saccadic inhibition in macaque monkeys
Khademi, F.; Zhang, T.; Baumann, M.; Buonocore, A.; Malevich, T.; Yu, Y.; Hafed, Z. M.
10.1101/2023.07.25.550484 — neuroscience — Posted on 2023-07-28
469 Multimodally trackable and clinically translatable platform for modelling human demyelinating brain diseases by temporally dispersed chemically induced lesions in thepig brain
Ancau, M.; Kumar, G. T.; Butenschoen, V. M.; Gempt, J.; Yakushev, I.; Nekolla, S.; Muehlau, M.; Scheunemann-Kutzenberger, C.; Heininger, S.; Loewe, B.; Loewe, E.; Baer, S.; Fischer, J.; Reiser, J.; Ayachit, S. S.; Liesche-Starnecker, F.; Schlegel, J.; Matiasek, K.; Schifferer, M.; Kirschke, J. S.; Misgeld, T.; Lueth, T.; Hemmer, B.
10.1101/2023.07.26.550644 — neuroscience — Posted on 2023-07-28
471 Dynamic local mRNA distribution and translation influence the postnatal molecular maturation of perivascular astrocytic processes
Avila-Gutierrez, K.; Slaoui, L.; Alvear, R.; Kozlowski, E.; Oudart, M. F.; Augustin, E.; Mailly, P.; Monnet, H.; Mignon, V.; Saubamea, B.; Boulay, A.-C.; Cohen-Salmon, M.
10.1101/2023.07.25.550497 — neuroscience — Posted on 2023-07-28
472 Parallel EEG assessment of different sound predictability levels in tinnitus
Brinkmann, P.; Devos, J. V.; van der Eerden, J. H.; Smit, J. V.; Janssen, M. L.; Kotz, S. A.; Schwartze, M.
10.1101/2023.07.25.550472 — neuroscience — Posted on 2023-07-28
473 Flicker light stimulation induces thalamocortical hyperconnectivity with LGN and higher-order thalamic nuclei
Amaya, I. A.; Schmidt, M. E.; Bartossek, M. T.; Kemmerer, J.; Kirilina, E.; Nierhaus, T.; Schmidt, T. T.
10.1101/2023.07.26.550646 — neuroscience — Posted on 2023-07-28
474 Constructed languages are processed by the same brain mechanisms as natural languages
Malik-Moraleda, S.; Taliaferro, M.; Shannon, S.; Jhingan, N.; Swords, S.; Peterson, D. J.; Frommer, P.; Okrand, M.; Sams, J.; Cardwell, R.; Freeman, C.; Fedorenko, E.
10.1101/2023.07.28.550667 — neuroscience — Posted on 2023-07-28
475 When Maturation is Not Linear: Brain Oscillatory Activity in the Process of Aging as Measured by Electrophysiology
Doval Moreno, S.; Lopez-Sanz, D.; Bruna, R.; Cuesta, P.; Anton-Toro, L.; Taguas, I.; Torres-Simon, L.; Chino, B.; Maestu, F.
10.1101/2023.07.26.550635 — neuroscience — Posted on 2023-07-28
482 How Absence Seizures Impair Sensory Perception: Insights from Awake fMRI and Simulation Studies in Rats
Stenroos, P.; Guillemain, I.; Tesler, F.; Montigon, O.; Collomb, N.; Stupar, V.; Destexhe, A.; Coizet, V.; David, O.; Barbier, E. L.
10.1101/2023.07.26.550701 — neuroscience — Posted on 2023-07-28
483 CAVE: Connectome Annotation Versioning Engine
Dorkenwald, S.; Schneider-Mizell, C. M.; Brittain, D.; Halageri, A.; Jordan, C.; Kemnitz, N.; Castro, M. A.; Silversmith, W.; Maitin-Shephard, J.; Troidl, J.; Pfister, H.; Gillet, V.; Xenes, D.; Bae, J. A.; Bodor, A. L.; Buchanan, J.; Bumbarger, D. J.; Elabbady, L.; Jia, Z.; Kapner, D.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yin, W.; Yu, S.-c.; Reid, R. C.; da Costa, N. M.; Seung, H. S.; Collman, F.
10.1101/2023.07.26.550598 — neuroscience — Posted on 2023-07-28
484 Analysis of behavioral flow resolves latent phenotypes
von Ziegler, L. M.; Roessler, F. K.; Sturman, O.; Waag, R.; Privitera, M.; Duss, S. N.; O'Connor, E. C.; Bohacek, J.
10.1101/2023.07.27.550778 — neuroscience — Posted on 2023-07-28
485 Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia
Abe, Y.; Yagishita, S.; Sano, H.; Sugiura, Y.; Dantsuji, M.; Suzuki, T.; Mochizuki, A.; Yoshimaru, D.; Hata, J.; Matsumoto, M.; Taira, S.; Takeuchi, H.; Okano, H.; Ohno, N.; Suematsu, M.; Inoue, T.; Nambu, A.; Watanabe, M.; Tanaka, K. F. F.
10.1101/2023.07.26.550763 — neuroscience — Posted on 2023-07-28
486 Hippocampal timestamp for goals
Montagrin, A.; Croote, D. E.; Preti, M. G.; Lerman, L.; Baxter, M. G.; Schiller, D.
10.1101/2023.07.27.550892 — neuroscience — Posted on 2023-07-28
491 Investigating Brain Alterations in the Dp1Tyb Mouse Model of Down Syndrome
Navacerrada, M. E. S.; Kim, E.; Siow, B.; Ma, D.; Gonzalez, L. R.; Simmons, C.; Hayward, D.; Gibbins, D.; Singh, N.; Strydom, A.; Fisher, E. M. C.; Tybulewicz, V. L. J.; Cash, D.
10.1101/2023.07.26.550698 — neuroscience — Posted on 2023-07-28
494 A Proxitome-RNA-capture Approach Reveals that Processing Bodies Repress Co-Regulated Hubs
Liu, C.; Mentzelopoulou, A.; Hatzianestis, I.; Tzagkarakis, E.; SKALTSOGIANNIS, V.; Ma, X.; Michalopoulou, V. A.; Romero-Campero, F. J.; Romero-Losada, A. B.; Sarris, P. F.; Marhavy, P.; Bölter, B.; Kanterakis, A.; Gutierrez-Beltran, E.; Moschou, P. N.
10.1101/2023.07.26.550742 — plant biology — Posted on 2023-07-28
495 Inhibition of skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity
Shahtout, J. L.; Eshima, H.; Ferrara, P. J.; Maschek, J. A.; Cox, J. E.; Drummond, M. J.; Funai, K.
10.1101/2023.07.25.550576 — physiology — Posted on 2023-07-28
498 An optogenetic approach to control and monitor inflammasome activation.
Nadjar, J.; Monnier, S.; Bastien, E.; Huber, A.-L.; Oddou, C.; Bardoulet, L.; Ichim, G.; Py, B.; Vanbelle, C.; Destaing, O.; Petrilli, V.
10.1101/2023.07.25.550490 — immunology — Posted on 2023-07-28
500 Variability in the local and global composition of human T-cell receptor repertoires during thymic development across cell types and individuals
Isacchini, G.; Quiniou, V.; Vantomme, H.; Stys, P.; Mariotti-Ferandiz, E.; Klatzmann, D.; Mora, T.; Walczak, A.; Nourmohammad, A.
10.1101/2023.07.25.550534 — immunology — Posted on 2023-07-28
503 3D electronic implants in subretinal space: long-term follow-up in rodents
Bhuckory, M. B.; Wang, B.; Chen, Z. C.; Shin, A.; Pham-Howard, D.; Shah, S.; Monkongpitukkul, N.; Galambos, L.; Kamins, T.; Mathieson, K.; Palanker, D.
10.1101/2023.07.25.550561 — neuroscience — Posted on 2023-07-28
507 Facial expression is a distinctive behavioural marker of pain processing in the brain
Picard, M.-E.; Kunz, M.; Chen, J.-I.; Coll, M.-P.; Vachon-Presseau, E.; Wager, T.; Rainville, P.
10.1101/2023.07.26.550504 — neuroscience — Posted on 2023-07-28
508 Modular Splicing is Linked to Evolution in the Synapse-Specificity Molecule Kirrel3
Traenkner, D.; Shennib, O.; Johnson, A.; Weinbrom, A.; Taylor, M. R.; Williams, M. E.
10.1101/2023.07.25.550563 — neuroscience — Posted on 2023-07-28
509 Learning attentional templates for value-based decision-making
Jahn, C. I.; Markov, N. T.; Morea, B.; Ebitz, B.; Buschman, T. J.
10.1101/2023.07.25.550426 — neuroscience — Posted on 2023-07-28
510 Complementary cognitive roles for D2-MSNs and D1-MSNs in interval timing
Bruce, R.; Weber, M. A.; Bova, A.; Volkman, R.; Jacobs, C.; Sivakumar, K.; Kim, Y.; Curtu, R.; Narayanan, N.
10.1101/2023.07.25.550569 — neuroscience — Posted on 2023-07-28
512 Tillering structures the genetic variability of wheat vegetative growth and its plasticity under water deficit
Parent, B.; Leveau, S.; Giunta, F.; Luchaire, N.; Cabrera-Bosquet, L.; Beauchene, K.; Jezequel, S.; Motzo, R.; Martre, P.
10.1101/2023.07.26.550706 — plant biology — Posted on 2023-07-28
513 Vhl deletion in Dmp1-expressing cells alters MEP metabolism and promotes stress erythropoiesis
Emery, J. M.; Chicana, B.; Taglinao, H.; Ponce, C.; Donham, C.; Padmore, H.; Sebastian, A.; Trasti, S. L.; Manilay, J. O.
10.1101/2023.07.25.550559 — physiology — Posted on 2023-07-28
514 Chimeric identities and reduced stiffness characterise the shoot apex of Arabidopsis stem cell mutants
Rambaud-Lavigne, L.; Chatterjee, A.; Bovio, S.; Battu, V.; Lavigne, Q.; Gundiah, N.; Boudaoud, A.; Das, P.
10.1101/2023.07.28.550972 — plant biology — Posted on 2023-07-28
516 Discovering host protein interactions specific for SARS-CoV-2 RNA genome
Giambruno, R.; Zacco, E.; Ugolini, C.; Vandelli, A.; Mulroney, L.; D'Onghia, M.; Giuliani, B.; Criscuolo, E.; Castelli, M.; Clementi, N.; Clementi, M.; Mancini, N.; Bonaldi, T.; Gustincich, S.; Leonardi, T.; Tartaglia, G. G.; Nicassio, F.
10.1101/2022.07.18.499583 — molecular biology — Posted on 2023-07-28
520 Responses of the hyper-diverse community of canopy-dwelling Hymenoptera to oak decline
Le Souchu, E.; Cours, J.; Cochenille, T.; Bouget, C.; Bankhead-Dronnet, S.; Braet, Y.; Burguet, P.; Gabard, C.; Galkowski, C.; Gereys, B.; Herbrecht, F.; Joncour, B.; Marhic, E.; Michez, D.; Buhl, P. N.; Noblecourt, T.; Notton, D. G.; Penigot, W.; Rasplus, J.-Y.; Robert, T.; Staverlokk, A.; Vincent-Barbaroux, C.; Salle, A.
10.1101/2023.07.25.550070 — ecology — Posted on 2023-07-28
522 Microtubule association of TRIM3 revealed by differential extraction proteomics
Glover, H.; Mendes, M.; Gomes-Neto, J.; Ruscilowicz-Jones, E. V.; Rigden, D.; Dittmar, G.; Urbe, S.; Clague, M. J.
10.1101/2023.07.27.549915 — cell biology — Posted on 2023-07-28
523 Diversity and biotechnological potential of filamentous fungi isolated from sediments of Basque estuaries
Otamendi, A.; Agirrezabala, Z.; Perez-Cruz, C.; Liebana, R.; Berregi, I.; Alonso-Saez, L.; Duenas, M. T.; Lanzen, A.; Etxebeste, O.
10.1101/2023.07.26.550687 — microbiology — Posted on 2023-07-28
525 Metabolic Nutrient Preferences of Vibrio mimicus: Leveraging Nucleotides and Oligopeptides from Yellow Catfish for Enhanced Infectivity
Feng, Y.; Wang, J.; Fan, W.; Geng, Y.; Huang, X.; Ouyang, P.; Chen, D.; Guo, H.; Deng, H.; Lai, W.; Zuo, Z.; Zhong, Z.
10.1101/2023.07.27.550872 — microbiology — Posted on 2023-07-28
526 Lesions in a songbird vocal circuit increase variability in song syntax
Koparkar, A.; Warren, T. L.; Charlesworth, J. D.; Shin, S.; Brainard, M. S.; Veit, L.
10.1101/2023.07.25.550508 — neuroscience — Posted on 2023-07-28
527 Molecular Basis of Kv1 Channel Downregulation and Its Epileptogenic Implications in Lgi1 Knock-out Mice
Ramirez-Franco, J.; Debreux, K.; Sangiardi, M.; Belghazi, M.; Kim, Y.; Lee, S.-H.; Leveque, C.; Seagar, M.; El Far, O.
10.1101/2023.07.24.550266 — neuroscience — Posted on 2023-07-28
529 Dopaminoceptive D1 and D2 neurons in ventral hippocampus arbitrate approach and avoidance in anxiety
Godino, A.; Salery, M.; Minier-Toribio, A. M.; Patel, V.; Fullard, J. F.; Parise, E. M.; Martinez-Rivera, F. J.; Morel, C.; Roussos, P.; Blitzer, R. D.; Nestler, E. J.
10.1101/2023.07.25.550554 — neuroscience — Posted on 2023-07-28
530 Taking time to compose thoughts with prefrontal schemata
Ryom, K. I.; Basu, A.; Stendardi, D.; Ciaramelli, E.; Treves, A.
10.1101/2023.07.25.550523 — neuroscience — Posted on 2023-07-28
531 KCNQ5 controls perivascular adipose tissue-mediated vasodilation
Tsvetkov, D.; Schleifenbaum, J.; Wang, Y.; Kassmann, M.; Polovitskaya, M.; Schütze, S.; Rothe, M.; Luft, F. C.; Jentsch, T. J.; Gollasch, M.
10.1101/2023.07.26.550617 — physiology — Posted on 2023-07-28
533 Cell type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells
Grimes, K.; Jeong, H.; Amoah, A.; Xu, N.; Niemann, J.; Raeder, B.; Hasenfeld, P.; Stober, C.; Rausch, T.; Benito, E.; Jann, J.-C.; Nowak, D.; Emini, R.; Hoenicka, M.; Liebold, A.; Ho, A. D.; Shuai, S.; Geiger, H.; Sanders, A. D.; Korbel, J. O.
10.1101/2023.07.25.550502 — genomics — Posted on 2023-07-28
534 The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
Guzman, M.; Moreno, E.; Casado, V.; Canela, E. I.; Costas-Insua, C.; Maroto, I. B.; Diez-Alarcia, R.; Urigüen, L.; Bellocchio, L.; Hermoso-Lopez, A.; Montero-Fernandez, C.; Alvaro-Blazquez, A.; Morales, P.; Rodriguez-Crespo, J. I.
10.1101/2023.07.24.550332 — neuroscience — Posted on 2023-07-28
536 Large-scale cortical networks are organized in structured cycles
van Es, M. W. J.; Higgins, C.; Gohil, C.; Quinn, A. J.; Vidaurre, D.; Woolrich, M. W.
10.1101/2023.07.25.550338 — neuroscience — Posted on 2023-07-28
537 Functional hierarchies in brain dynamics characterized by signal reversibility in ferret cortex
Idesis, S.; Geli, S.; Faskowitz, J.; Vohryzek, J.; Sanz Perl, Y.; Pieper, F.; Galindo-Leon, E.; Engel, A. K.; Deco, G.
10.1101/2023.07.26.550669 — neuroscience — Posted on 2023-07-28
538 Species -Shared and -Unique Gyral Peaks on Human and Macaque Brains
Zhang, S.; Zhang, T.; Cao, G.; Zhou, J.; He, Z.; Li, X.; Ren, Y.; Jiang, X.; Guo, L.; Han, J.; Liu, T.
10.1101/2023.07.26.550760 — neuroscience — Posted on 2023-07-28
543 Non-severe burns induce a prolonged systemic metabolic phenotype indicative of a persistent inflammatory response post-injury
Ryan, M. J.; Raby, E.; Masuda, R.; Lodge, S.; Nitschke, P.; Maker, G. L.; Wist, J.; Holmes, E.; Whiley, L.; Wood, F. M.; Nicholson, J. K.; Fear, M. W.; Gray, N.
10.1101/2023.04.24.537960 — systems biology — Posted on 2023-07-28
548 Cytokinins control secondary cell wall formation in the inflorescence stem of Arabidopsis
Didi, V.; Arnaud, D.; Pacinkova, A.; Jupa, R.; Cegan, R.; Melnikava, A.; Vasickova, J.; Benitez, M.; Unda, F.; Dobisova, T.; Riber, W.; Dostalova, Z.; Mansfield, S. D.; Novak, O.; Strnad, M.; Hobza, R.; Gloser, V.; Budinska, E.; Hejatko, J.
10.1101/2023.07.26.550726 — plant biology — Posted on 2023-07-28
549 Analysis of RyR2 distribution in HEK293 cells and mouse cardiac myocytes using 3D MINFLUX microscopy
Clowsley, A. H.; Meletiou, A.; Lucinskaite, E.; Jansen, I.; Jones, P. P.; Louch, W. E.; Soeller, C.
10.1101/2023.07.26.550636 — physiology — Posted on 2023-07-28
556 A conserved fertilization complex of Izumo1, Spaca6, and Tmem81 mediates sperm-egg interaction in vertebrates
Deneke, V. E.; Blaha, A.; Lu, Y.; Draper, J. M.; Phan, C. S.; Panser, K.; Schleiffer, A.; Jacob, L.; Humer, T.; Stejskal, K.; Krssakova, G.; Handler, D.; Kamoshita, M.; Vance, T. D. R.; Roitinger, E.; Lee, J. E.; Ikawa, M.; Pauli, A.
10.1101/2023.07.27.550750 — developmental biology — Posted on 2023-07-28
557 The Mediterranean mussel, Mytilus galloprovincialis, a novel model for developmental studies of mollusks
Miglioli, A.; Tredez, M.; Boosten, M.; Sant, C.; Carvalho, J. E.; Dru, P.; Canesi, L.; Schubert, M.; Dumollard, R.
10.1101/2023.07.27.550798 — developmental biology — Posted on 2023-07-28
560 Human receptive endometrial organoid for deciphering the implantation window
Zhao, H.; Wu, K.; Chen, Z.-J.; Zhang, Y.; Zhao, R.; Yang, C.; Song, J.; Liu, P.; Li, Y.; Liu, B.; Li, T.; Yin, C.; Lu, M.; Hou, Z.; Zhang, C.
10.1101/2023.07.27.550771 — cell biology — Posted on 2023-07-28
561 Universal length fluctuations of actin structures found in cells
Rosario, A. A. A.; McInally, S. G.; Jelenkovic, P. R.; Goode, B. L.; Kondev, J.
10.1101/2023.07.27.550898 — cell biology — Posted on 2023-07-28
562 A new mechanism of posttranslational polyglutamylation regulates phase separation and signaling of the Wnt pathway protein Dishevelled.
Kravec, M.; Sedo, O.; Nedvedova, J.; Micka, M.; Sulcova, M.; Gomoryova, K.; Potesil, D.; Ganji, R. S.; Cervenka, I.; Zdrahal, Z.; Harnos, J.; Tripsianes, K.; Janke, C.; Barinka, C.; Bryja, V.
10.1101/2023.07.28.550915 — cell biology — Posted on 2023-07-28
564 ThermoMaze: A behavioral paradigm for readout of immobility-related brain events
Voroslakos, M.; Zhang, Y.; McClain, K.; Huszar, R.; Rothstein, A.; Buzsaki, G.
10.1101/2023.07.25.550518 — neuroscience — Posted on 2023-07-28
570 The use of social information in vulture flight decisions
Sassi, Y.; Nouzieres, B.; Scacco, M.; Tremblay, Y.; Duriez, O.; Robira, B.
10.1101/2023.07.26.550671 — animal behavior and cognition — Posted on 2023-07-28
571 Macrophages heterogeneity and significance during human fetal pancreatic development
Migliorini, A.; Ge, S.; Atkins, M. H.; Sambathkumar, R.; Sing, A.; Chua, C.; Gehring, A. J.; Keller, G. M.; Notta, F.; Nostro, M. C.
10.1101/2023.07.27.549142 — developmental biology — Posted on 2023-07-28
572 Region-specific reversal of epidermal planar polarity in the fancy rosette mouse
Cetera, M.; Sharan, R.; Hayward-Lara, G.; Phillips, B.; Biswas, A.; Halley, M.; Beall, E.; vonHoldt, B.; Devenport, D.
10.1101/2023.07.27.550849 — developmental biology — Posted on 2023-07-28
574 PROTECTIVE EFFECTS OF TRITERPENOID BETULIN ON TYPE 2 DIABETES MELLITUS IN RATS
Shlyahtun, A. H.; Maksimchyk, Y. Z.; Zakrzeska, A.; Sutsko, I. P.; Raduta, A. F.; Buksha, E. V.; Bahdzevich, Y. V.; Kitlas, P.; Tomulewicz, M.
10.1101/2023.07.27.550802 — biochemistry — Posted on 2023-07-27
577 ZBTB48 is a pioneer factor regulating B-cell-specific CIITA expression
Rane, G.; Kuan, V. L. S.; Wang, S.; Mok, M. M. H.; Khanchandani, V.; Hansen, J.; Norvaisaite, I.; Yong, W. K.; Jahn, A.; Mukundan, V.; Shi, Y.; Osato, M.; Li, F.; Kappei, D.
10.1101/2023.07.25.550481 — immunology — Posted on 2023-07-27
578 Functional and Structural Characterization of an IclR Family Transcription Factor for the Development of Dicarboxylic Acid Biosensors
Pham, C.; Nasr, M.; Skarina, T.; Di Leo, R.; Kwan, D. H.; Marting, V. J. J.; Stogios, P. J.; Mahadevan, R.; Savchenko, A.
10.1101/2023.07.27.550818 — synthetic biology — Posted on 2023-07-27
580 Systematic assessment of long-read RNA-seq methods for transcript identification and quantification
Pardo-Palacios, F. J.; Wang, D.; Reese, F.; Diekhans, M.; Carbonell-Sala, S.; Williams, B.; Loveland, J. E.; De Maria, M.; Adams, M. S.; Balderrama-Gutierrez, G.; Behera, A. K.; Gonzalez, J. M.; Hunt, T.; Lagarde, J.; Liang, C. E.; Li, H.; Meade, M. J.; Amador, D. A. M.; Prjibelski, A. D.; Birol, I.; Bostan, H.; Brooks, A. M.; Celik, M. H.; Chen, Y.; Du, M. R. M.; Felton, C.; Goke, J.; Hafezqorani, S.; Herwig, R.; Kawaji, H.; Lee, J.; Li, J.-L.; Lienhard, M.; Mikheenko, A.; Mulligan, D.; Nip, K. M.; Pertea, M.; Ritchie, M. E.; Sim, A. D.; Tang, A. D.; Wan, Y. K.; Wang, C.; Wong, B. Y.; Yang, C
10.1101/2023.07.25.550582 — genomics — Posted on 2023-07-27
581 Recurrent Multiple Myeloma DIS3 alleles arise early but are later counter-selected due to toxicity
Kulinski, T.; Gewartowska, O.; Mroczek, S.; Szpila, M.; Salas, K.; Liudkovska, V.; Dziembowski, A.
10.1101/2023.07.27.550471 — molecular biology — Posted on 2023-07-27
582 Multiple Myeloma associated DIS3 mutations drive AID-dependent IgH Translocations
Kulinski, T. M.; Gewartowska, O.; Mahe, M.; Kasztelan, K.; Durys, J.; Seraphin, B.; Dziembowski, A.
10.1101/2023.07.27.550610 — molecular biology — Posted on 2023-07-27
584 Plasma Activated Water as a Pre-Treatment Strategy in the Context of Biofilm-Infected Chronic Wounds
Vyas, H. K. N.; Xia, B.; Alam, D.; Gracie, N. P.; Rothwell, J. G.; Rice, S. A.; Carter, D.; Cullen, P. J.; Mai-Prochnow, A.
10.1101/2023.07.26.550769 — microbiology — Posted on 2023-07-27
585 Production of Infectious Reporter Murine Norovirus by VP2 trans-Complementation
Ishiyama, R.; Yoshida, K.; Oikawa, K.; Takai-Todaka, R.; Kato, A.; Kanamori, K.; Nakanishi, A.; Haga, K.; Katayama, K.
10.1101/2023.07.27.550866 — microbiology — Posted on 2023-07-27
586 Hippocampal protein aggregation signatures fully distinguish pathogenic and wildtype UBQLN2 in amyotrophic lateral sclerosis
Thumbadoo, K. M.; Dieriks, B. V.; Murray, H. C.; Swanson, M. E.; Yoo, J. H.; Mehrabi, N. F.; Turner, C.; Dragunow, M.; Faull, R. L.; Curtis, M. A.; Siddique, T.; Shaw, C. E.; Henden, L.; Williams, K. L.; Nicholson, G. A.; Scotter, E. L.
10.1101/2022.01.12.475792 — neuroscience — Posted on 2023-07-27
587 Systematic exploration of prokaryotic form I rubisco maximal carboxylation rates
de Pins, B.; Greenspoon, L.; Bar-On, Y. M.; Shamshoum, M.; Ben-Nissan, R.; Milshtein, E.; Davidi, D.; Sharon, I.; Mueller-Cajar, O.; Noor, E.; Milo, R.
10.1101/2023.07.27.550689 — systems biology — Posted on 2023-07-27
588 Innate Immune Signaling in Hearts and Buccal Mucosa Cells of Patients with Arrhythmogenic Cardiomyopathy
Bueno-Beti, C.; Tafuni, A.; Chelko, S. P.; Sheppard, M. N.; Field, E.; Tollit, J.; Heenan, I. K.; Barnes, A.; Taylor, M. R.; Mestroni, L.; Kaski, J. P.; Saffitz, J. E.; Asimaki, A.
10.1101/2023.07.25.550526 — pathology — Posted on 2023-07-27
590 RNA-mediated Allosteric Activation in CRISPR-Cas13a
Sinha, S.; Molina Vargas, A. M.; Arantes, P. R.; Patel, A. C.; O'Connell, M. R.; Palermo, G.
10.1101/2023.07.27.550797 — biophysics — Posted on 2023-07-27
591 Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model
Lee, M.-S.; Sivapatham, A.; Leiferman, E. M.; Jiao, H.; Lu, Y.; Nemke, B. W.; Leiferman, M.; Markel, M. D.; Li, W.-J.
10.1101/2023.07.25.550409 — bioengineering — Posted on 2023-07-27
595 Chromatin-associated RNA Dictates the ecDNA Interactome in the Nucleus
Liang, Z.; Gilbreath, C.; Liu, W.; Wang, Y.; Zhang, M. Q.; Zhang, D.-E.; Wu, S.; Fu, X.-D.
10.1101/2023.07.27.550855 — genomics — Posted on 2023-07-27
598 Beyond 40 fluorescent probes for deep phenotyping of blood mononuclear cells, using spectral technology.
Schmutz, S.; Commere, P.-H.; Montcuquet, N.; Cumano, A.; Ait-Mansour, C.; Novault, S.; Hasan, M.
10.1101/2023.07.27.550830 — cell biology — Posted on 2023-07-27
600 Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation
Urbauer, E.; Aguanno, D.; Mindermann, N.; Omer, H.; Metwaly, A.; Khaloian, S.; Reitmeier, S.; Remke, M.; Jarosch, S.; Huber, S.; Busch, D. H.; Stecher, B.; Allez, M.; Steiger, K.; Rath, E.; Haller, D.
10.1101/2023.07.27.549844 — microbiology — Posted on 2023-07-27
601 Fever like temperature impacts on Staphylococcus aureus and Pseudomonas aeruginosa interaction, physiology, and virulence both in vitro and in vivo
Solar Venero, E. C.; Galeano, M. B.; Luqman, A.; Ricardi, M.; Serral, F.; Fernandez Do Porto, D.; Robaldi, S. A.; Ashari, B. A. Z.; Munif, T. H.; Egoburo, D. E.; Nemirovsky, S.; Escalante, J.; Nishimura, B.; Ramirez, M. S.; Götz, F.; Tribelli, P. M.
10.1101/2023.03.21.529514 — microbiology — Posted on 2023-07-27
604 Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs
Gao, K. M.; Chiang, K.; Korkmaz, F. T.; Janardhan, H. P.; Trivedi, C. M.; Quinton, L. J.; Gingras, S. M.; Fitzgerald, K. A.; Marshak-Rothstein, A.
10.1101/2023.07.27.550897 — immunology — Posted on 2023-07-27
605 Laser microdissection, proteomics and multiplex immunohistochemistry: a bumpy ride into the study of paraffin-embedded fetal and pediatric lung tissues.
Cardoso dos Santos, L. M.; Ventura Avila, Y.; Schvartz, D.; Rougemont, A.-L.; Bochaton-Piallat, M.-L.; Ruchonnet-Metrailler, I.
10.1101/2023.07.25.550475 — pathology — Posted on 2023-07-27
607 Site-specific proximity labeling at single residue resolution for identification of protein partners in vitro and on cells
Bartholow, T. G.; Burroughs, P.; Elledge, S. K.; Byrnes, J. R.; Kirkemo, L. L.; Garda, V.; Leung, K. K.; Wells, J. A.
10.1101/2023.07.27.550738 — biochemistry — Posted on 2023-07-27
609 A Novel Homeostatic Mechanism Tunes PI(4,5)P2-dependent Signaling at the Plasma Membrane
Wills, R. C.; Doyle, C. P.; Zewe, J. P.; Pacheco, J.; Hansen, S. D.; Hammond, G. R.
10.1101/2022.06.30.498262 — cell biology — Posted on 2023-07-27
610 IF1 controls UCP1-dependent mitochondrial bioenergetics in brown adipocytes
Brunetta, H. S.; Jung, A. S.; Francisco, A.; Castilho, R. F.; Mori, M. A.; Bartelt, A.
10.1101/2023.07.27.550888 — cell biology — Posted on 2023-07-27
614 A neural mechanism for discriminating social threat from social safety
Kassraian, P.; Bigler, S.; Gilly, D. M.; Shrotri, N.; Siegelbaum, S. A.
10.1101/2023.07.04.547723 — neuroscience — Posted on 2023-07-27
624 Paracrine enhancement of tumor cell proliferation provides indirect stroma-mediated chemoresistance via acceleration of tumor recovery between chemotherapy cycles.
Miroshnychenko, D.; Miti, T.; Kumar, P.; Miller, A. K.; Laurie, M.; Giraldo, N.; Bui, M. M.; Altrock, P. M.; Basanta, D.; Marusyk, A.
10.1101/2023.02.07.527543 — cancer biology — Posted on 2023-07-27
627 Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures
Vogt, C. C.; Zipple, M. N.; Sprockett, D. D.; Miller, C. H.; Hardy, S. X.; Arthur, M. K.; Greenstein, A. M.; Colvin, M. S.; Michel, L. M.; Moeller, A. H.; Sheehan, M. J.
10.1101/2022.04.19.488643 — animal behavior and cognition — Posted on 2023-07-27
628 Genomic insights into Plasmodium vivax population structure and diversity in central Africa
Gartner, V.; Redelings, B. D.; Gaither, C.; Parr, J. B.; Kalonji, A.; Phanzu, F.; Brazeau, N. F.; Juliano, J. J.; Wray, G. A.
10.1101/2022.12.16.520826 — evolutionary biology — Posted on 2023-07-27
629 Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid nanodisc environment
Koeck, Z.; Schnelle, K.; Persechino, M.; Umbach, S.; Schihada, H.; Januliene, D.; Parey, K.; Pockes, S.; Kolb, P.; Doetsch, V.; Moeller, A.; Hilger, D.; Bernhard, F.
10.1101/2023.07.27.550782 — molecular biology — Posted on 2023-07-27
630 Interaction of SCoV-2 NSP7 or NSP8 alone may cause constriction of the RNA entry channel in NSP12: Implications for novel RdRp inhibitor drug discovery
Singh, D.; Kushwaha, T.; Kulandaisamy, R.; Kumar, V.; Baswal, K.; Tiwari, S. H.; Ghorai, A.; Kumar, M.; Kumar, S.; Polamarasetty, A.; Sehgal, D.; Katika, M. R.; Gadde, S.; Cote, M.; Kayampeta, S. R.; Appaiahgari, M. B.; Inampudi, K. K.
10.1101/2023.07.26.550660 — molecular biology — Posted on 2023-07-27
631 Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders
Yang, K.; Hasegawa, Y.; Bhattarai, J. P.; Hua, J.; Dower, M.; Etyemez, S.; Prasad, N.; Duvall, L. G.; Paez, A. K.; Smith, A.; Wang, Y.; Zhang, Y.-F.; Lane, A. P.; Ishizuka, K.; Kamath, V.; Ma, M.; Kamiya, A.; Sawa, A.
10.1101/2022.09.23.509224 — molecular biology — Posted on 2023-07-27
633 Trophic ecology of the African riverine elephant fishes (Mormyridae)
Sommer, G. M.; Njom, S. D.; Indermaur, A.; Bitja Nyom, A. R.; Horka, P.; Kukla, J.; Musilova, Z.
10.1101/2023.06.07.543841 — zoology — Posted on 2023-07-27
636 cloudrnaSPAdes: Isoform assembly using bulk barcoded RNA sequencing data
Meleshko, D.; Prjbelski, A. D.; Rayko, M.; Tomescu, A. I.; Tilgner, H.; Hajirasouliha, I.
10.1101/2023.07.25.550587 — bioinformatics — Posted on 2023-07-27
639 Human Plasma Proteomic Profile of Clonal Hematopoiesis
Yu, Z.; Vromman, A.; Nguyen, N. Q. H.; Vellarikkal, S. K.; Uddin, M. M.; Niroula, A.; Griffin, G.; Honigberg, M. C.; Lin, A. E.; Gibson, C. J.; Katz, D. H.; Tahir, U.; Haidermota, S.; Ganesh, S.; Antoine, T.; Weinstock, J.; Austin, T. R.; Vasan, R. S.; peloso, G. M.; Hornsby, W.; Ganz, P.; Manson, J. E.; Haring, B.; Kooperberg, C. L.; Reiner, A. P.; Bis, J. C.; Psaty, B. M.; Min, Y.-I.; Correa, A.; Lange, L. A.; Post, W.; Rotter, J. I.; Rich, S. S.; Wilson, J. G.; Ebert, B. L.; Yu, B.; Ballantyne, C. M.; Coresh, J.; Sankaran, V. G.; Bick, A. G.; Jaiswal, S.; Libby, P.; Gerszten, R. E.; NHLBI T
10.1101/2023.07.25.550557 — genetics — Posted on 2023-07-27
640 Response of microbial eukaryote community to the oligotrophic waters of the Gulf of Mexico: a plausible scenario for warm and stratified oceans
Sidon Cesena, K.; Martinez- Mercado, M. A.; Chong-Robles, J.; Ortega-Saad, Y.; Camacho-Ibar, V. F.; Linacre, L.; Lago-Leston, A.
10.1101/2023.07.26.548711 — ecology — Posted on 2023-07-27
643 Seed tuber imprinting shapes the next-generation potato microbiome
Song, Y.; Spooren, J.; Jongekrijg, C. D.; Manders, E. H. H.; de Jonge, R.; Pieterse, C. M. J.; Bakker, P. A. H. M.; Berendsen, R. L.
10.1101/2023.07.27.549298 — microbiology — Posted on 2023-07-27
644 Competitive fitness and homologous recombination of SARS-CoV-2 variants of concern
Qin, C.-F.; Chen, Q.; Si, Q.; Zhou, H.; Deng, Y.-Q.; Shi, P.-D.; Zhao, H.; Li, X.-F.; Huang, X.-Y.; Wu, Y.; Guo, Y.; Pei, G.; Wang, Y.; Sun, S.-Q.; Du, Z.-M.; Cui, Y.; Fan, H.
10.1101/2023.07.26.550688 — microbiology — Posted on 2023-07-27
645 The transcriptome landscape of developing barley seeds reveals H3K27me3 dynamics in endosperm tissues
Kovacik, M.; Nowicka, A.; Zwyrtkov, J.; Strejckova, B.; Vardanega, I.; Esteban, E. N.; Pasha, A.; Kaduchova, K.; Krautsova, M.; Safar, J.; Provart, N. J.; Simon, R.; Pecinka, A.
10.1101/2023.07.26.550659 — plant biology — Posted on 2023-07-27
646 Field margins as substitute habitat for the conservation of birds in agricultural wetlands
Mallet, P.; Bechet, A.; Sirami, C.; Mesleard, F.; Blanchon, T.; Calatayud, F.; Dagonet, T.; Gaget, E.; Leray, C.; Galewski, T.
10.1101/2022.05.05.490780 — ecology — Posted on 2023-07-27
647 Innate Immune Signaling in Hearts and Buccal Mucosa Cells of Patients with Arrhythmogenic Cardiomyopathy
Bueno-Beti, C.; Tafuni, A.; Chelko, S. P.; Sheppard, M. N.; Field, E.; Tollit, J.; Heenan, I. K.; Barnes, A.; Taylor, M. R.; Mestroni, L.; Kaski, J. P.; Saffitz, J. E.; Asimaki, A.
10.1101/2023.07.25.550526 — pathology — Posted on 2023-07-27
648 The Vk*MYC Mouse Model recapitulates human multiple myeloma evolution and genomic diversity
MAURA, F.; Coffey, D. G.; Stein, C. K.; Braggio, E.; Ziccheddu, B.; Sharik, M. E.; Du, M.; Alvarado, Y. T.; Shi, C.-X.; Zhu, Y. X.; Meermeier, E. W.; Morgan, G. J.; Landgren, O.; Bersagel, L.; Chesi, M.
10.1101/2023.07.25.550482 — cancer biology — Posted on 2023-07-27
651 BRCA1 and BRCA2 germline mutations driven signaling pathway alterations are sufficient to initiate breast tumorigenesis by the PIK3CAH1047R oncogene.
Bhat-Nakshatri, P.; Khatpe, A. S.; Chen, D.; Batic, K.; Mang, H.; Herodotou, C.; McGuire, P. C.; Xuei, X.; Gao, H.; Liu, Y.; Sandusky, G.; Storniolo, A. M.; Nakshatri, H.
10.1101/2023.07.26.550741 — cancer biology — Posted on 2023-07-27
654 Enhancer plasticity in endometrial tumorigenesis demarcates non-coding driver mutations and alterations in 3D genome organization to stimulate oncogene expression
Gregoricchio, S.; Kojic, A.; Hoogstraat, M.; Schuurman, K.; Stelloo, S.; Severson, T. M.; O'Mara, T. A.; Droog, M.; Singh, A. A.; Glubb, D. M.; Wessels, L. F. A.; Vermeulen, M.; van Leeuwen, F.; Zwart, W.
10.1101/2023.07.25.550368 — cancer biology — Posted on 2023-07-27
656 Polyamine transport inhibition and cisplatin synergistically enhance tumor control through oxidative stress in murine head and neck cancer models
Yassin-Kassab, A.; Wang, N.; Foley, J. R.; Murray Stewart, T. R.; Burns, M. R.; Casero, R. A.; Harbison, R. A.; Duvvuri, U.
10.1101/2023.07.25.550524 — cancer biology — Posted on 2023-07-27
665 PMS1 as a target for splice modulation to prevent somatic CAG repeat expansion in Huntington's disease
McLean, Z. L.; Gao, D.; Correia, K.; Roy, J. C. L.; Shibata, S.; Farnum, i. N.; Valdepenas-Mellor, Z.; Rapuru, M.; Morini, E.; Ruliera, j.; Gillis, T.; Lucente, D.; Kleinstiver, B. P.; Lee, J.-M.; MacDonald, M. E.; Wheeler, v.; Pinto, R. M.; Gusella, J. F.
10.1101/2023.07.25.550489 — genetics — Posted on 2023-07-27
669 TRPV1 controls innate immunity during Citrobacter rodentium enteric infection
Cremin, M.; Tay, E. X. Y.; Ramirez, V. T.; Murrray, K.; Nichols, R. K.; Brust-Mascher, I.; Reardon, C.
10.1101/2023.07.26.550772 — immunology — Posted on 2023-07-27
673 Cell-type specific molecular signatures of aging revealed in a brain-wide transcriptomic cell-type atlas
Jin, K.; Yao, Z.; van Velthoven, C. T. J.; Kaplan, E. S.; Glattfelder, K.; Barlow, S. T.; Boyer, G.; Carey, D.; Casper, T.; Chakka, A. B.; Chakrabarty, R.; Clark, M.; Departee, M.; Desierto, M.; Gary, A.; Gloe, J.; Goldy, J.; Guilford, N.; Guzman, J.; Hirschstein, D.; Lee, C.; Liang, E.; Pham, T.; Reding, M.; Ronellenfitch, K.; Ruiz, A.; Sevigny, J.; Shapovalova, N.; Shulga, L.; Sulc, J.; Torkelson, A.; Tung, H.; Levi, B.; Sunkin, S. M.; Dee, N.; Esposito, L.; Smith, K.; Tasic, B.; Zeng, H.
10.1101/2023.07.26.550355 — neuroscience — Posted on 2023-07-27
675 Local Disordered Region Sampling (LDRS) for Ensemble Modeling of Proteins with Experimentally Undetermined or Low Confidence Prediction Segments
Liu, Z. H.; Teixeira, J. M. C.; Zhang, O.; Tsangaris, T. E.; Li, J.; Gradinaru, C. C.; Head-Gordon, T.; Forman-Kay, J. D.
10.1101/2023.07.25.550520 — biophysics — Posted on 2023-07-27
678 Physics-based inverse design of cholesterolattracting transmembrane helices reveals aparadoxical role of hydrophobic length
Methorst, J.; Verwei, N.; Hoffmann, C.; Chodnicki, P.; Sansevrino, R.; Wang, H.; van Hilten, N.; Aschmann, D.; Kros, A.; Andreas, L.; Czub, J.; Milovanovic, D.; Risselada, H. J.
10.1101/2021.07.01.450699 — biophysics — Posted on 2023-07-27
680 DMRT1 is a Testis Determining Gene in Rabbits and is Also Essential for Female Fertility
Dujardin, E.; Andre, M.; Dewaele, A.; Mandon-Pepin, B.; Poulat, F.; Frambourg, A.; Thepot, D.; Jouneau, L.; Jolivet, G.; Pailhoux, E.; Pannetier, M.
10.1101/2023.01.13.523925 — developmental biology — Posted on 2023-07-27
682 iFlpMosaics: A method for the ratiometric induction and high-throughput comparative analysis of mutant and wildtype cells
Garcia-Gonzalez, I.; Gambera, S.; Regano, A.; Rocha, S. F.; Garcia-Ortega, L.; Lytvyn, M.; Sanchez-Munoz, M. S.; Garcia-Cabero, A.; Diago-Domingo, L.; Zagorac, I.; Luo, W.; Fernandez-Chacon, M.; Casquero-Garcia, V.; Lunella, F. F.; Benedito, R.
10.1101/2023.05.09.540000 — cell biology — Posted on 2023-07-27
683 Bimodal inference in humans and mice
Weilnhammer, V. A.; Stuke, H.; Standvoss, K.; Sterzer, P.
10.1101/2021.08.20.457079 — neuroscience — Posted on 2023-07-27
684 Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper
Jiang, Y.; Zhang, X.-Y.; Li, S.; Xie, Y.-C.; Yang, Y.; Pu, Z.; Zhang, L.; Lu, J.-B.; Huang, H.-J.; Zhang, C.-X.; He, S. Y.
10.1101/2023.05.24.542203 — plant biology — Posted on 2023-07-27
685 Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction
Leinenga, G.; To, X. V.; Bodea, L.-G.; Yousef, J.; Richter-Stretton, G.; Palliyaguru, T.; Chicoteau, A.; Dagley, L.; Nasrallah, F.; Gotz, J.
10.1101/2023.06.16.545394 — neuroscience — Posted on 2023-07-27
688 Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements
Trauernicht, M.; Rastogi, C.; Manzo, S. G.; Bussemaker, H. J.; van Steensel, B.
10.1101/2023.07.24.549988 — genomics — Posted on 2023-07-27
689 The membrane-actin linkers ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics.
Verdys, P.; Rey Barroso, J.; Vermeil, J.; Bergert, M.; Sanchez, T.; Metais, A.; Mangeat, T.; Bellard, E.; Bigot, C.; Girard, J.-P.; Maridonneau-Parini, I.; Verollet, C.; Lagarrigue, F.; Diz-Munoz, A.; Heuvingh, J.; Piel, M.; Du Roure, O.; Le Cabec, V.; Carreno, S.; Poincloux, R.
10.1101/2023.07.27.550674 — cell biology — Posted on 2023-07-27
691 Benchmarking DNA Isolation Methods for Marine Metagenomics Studies
Demkina, A.; Slonova, D.; Mamontov, V.; Konovalova, O.; Yurikova, D.; Rogozhin, V.; Belova, V.; Korostin, D.; Sutormin, D.; Severinov, K. V.; Isaev, A.
10.1101/2023.07.25.550485 — bioinformatics — Posted on 2023-07-27
692 Whole-genome sequencing reveals diverse mechanisms underlying quantitative pathogenicity and host adaptation in a fungal plant pathogen
AMEZROU, R.; DUCASSE, A.; COMPAIN, J.; LAPALU, N.; PITARCH, A.; DUPONT, L.; CONFAIS, J.; GOYEAU, H.; KEMA, G. H.; CROLL, D.; AMSELEM, J.; SANCHEZ-VALLET, A.; MARCEL, T. C.
10.1101/2022.12.23.521735 — genomics — Posted on 2023-07-27
693 The cellular landscape of the endochondral bone highlights its multipotent and immunomodulatory features during the transition to extrauterine life
Rueda, A. D.; Salvador-Martinez, I.; Sospedra-Arrufat, I.; Alcaina-Caro, A.; Fernandez-Minan, A.; Burgos-Ruiz, A. M.; Cases, I.; Mohedano, A.; Tena, J. J.; Heyn, H.; Lopez-Rios, J.; Nusspaumer, G.
10.1101/2023.07.18.549529 — cell biology — Posted on 2023-07-27
695 O-GlcNAcylation of Keratin 18 coordinates TCA cycle to promote cholangiocarcinoma progression
Meng, X.; Zhou, Y.; Xu, L.; Wang, C.; Tian, X.; Zhang, X.; Hao, Y.; Cheng, B.; Wang, L.; Liu, J.; Xie, R.
10.1101/2023.07.23.550247 — cancer biology — Posted on 2023-07-27
701 Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Zhang, G.; Zhang, Y.; Young, R.; Garvanska, D.; Song, C.; Zhai, Y.; Wang, Y.; Jiang, H.; Fang, J.; Nilsson, J.; Alfieri, C.
10.1101/2023.07.26.550666 — cell biology — Posted on 2023-07-27
702 Disease-associated gut microbiome and metabolome changes in chronic low back pain patients with bone marrow lesions
Li, W.; Tu, J.; Zheng, J.; Das, A.; Yan, Q.; Jiang, X.; Ding, W.; Bai, X.; Lai, K.; Yang, S.; Yang, C.; Zou, J.; Diwan, A. D.; Zheng, Z.
10.1101/2023.07.26.550629 — cell biology — Posted on 2023-07-27
703 The Kelch13 compartment is a hub of highly divergent vesicle trafficking proteins in malaria parasites
Schmidt, S.; Wichers-Misterek, J. S.; Behrens, H. M.; Birnbaum, J.; Henshall, I.; Dröge, J.; Jonscher, E.; Flemming, S.; Castro-Pena, C.; Mesen-Ramirez, P.; Spielmann, T.
10.1101/2022.12.15.520209 — cell biology — Posted on 2023-07-27
705 Temporal dynamics of the multi-omic response to endurance exercise training across tissues
MoTrPAC Study Group, ; Amar, D.; Gay, N. R.; Jean Beltran, P. M.; Adkins, J. N.; Almagro Armenteros, J. J.; Ashley, E.; Avila-Pacheco, J.; Bae, D.; Bararpour, N.; Burant, C.; Clish, C.; Cutter, G.; Dasari, S.; Dennis, C.; Evans, C. R.; Fernandez, F. M.; Gaul, D.; Ge, Y.; Gerszten, R.; Goodyear, L. J.; Hou, Z.; Ilkayeva, O.; Ivanova, A. A.; Jimenez-Morales, D.; Kachman, M. T.; Keshishian, H.; Kraus, W. E.; Lanza, I. R.; Li, J.; Lindholm, M. E.; Lira, A. C.; Many, G. M.; Marwaha, S.; Miller, M. E.; Muehlbauer, M. J.; Nair, K. S.; Nair, V. D.; Natarajan Raja, A.; Newgard, C.; Ortlund, E. A.; Pie
10.1101/2022.09.21.508770 — molecular biology — Posted on 2023-07-27
708 Human Adult Neurogenesis Loss Underlies Cognitive Decline During Epilepsy Progression
Ammothumkandy, A.; Corona, L.; Ravina, K.; Wolseley, V.; Nelson, J.; Atai, N.; Abedi, A.; Jimenez, N.; Armacost, M.; D'Orazio, L. M.; Zuverza-Chavarria, V.; Cayce, A.; McCleary, C.; Nune, G.; Kalayjian, L.; Lee, D.; Lee, B.; Heck, C.; Chow, R. H.; Russin, J. J.; Liu, C. Y.; Smith, J. A.; Bonaguidi, M. A.
10.1101/2022.09.12.507339 — neuroscience — Posted on 2023-07-27
710 Speech recognition from MEG data using covariance filters
Verkhlyutov, V. M.; Vvedensky, V. L.; Gurtovoy, K. G.; Burlakov, E. O.; Martynova, O. V.
10.1101/2023.06.22.546174 — neuroscience — Posted on 2023-07-27
714 Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding
Wiedemann, C.; Whittaker, J. J.; Perez Carrillo, V. H.; Goretzki, B.; Dajka, M.; Tebbe, F.; Harder, J.-M.; Krajczy, P.; Joseph, B.; Hausch, F.; Guskov, A.; Hellmich, U. A.
10.1101/2023.04.24.538046 — biophysics — Posted on 2023-07-27
718 Noncanonical usage of stop codons in ciliates expands proteins with structurally flexible Q-rich motifs
Chuang, C.-N.; Liu, H.-C.; Woo, T.-T.; Hu, H.-T.; Chao, J.-L.; Chen, C.-Y.; Hsueh, Y.-P.; Wang, T.-F.
10.1101/2020.12.08.407247 — biochemistry — Posted on 2023-07-26
720 The Hypolimnas misippus genome supports a common origin of the W chromosome in Lepidoptera
Orteu, A.; McCarthy, S. A.; Hornett, E. A.; Gemmell, M. R.; Reynolds, L. A.; Warren, I. A.; Gordon, I. J.; Hurst, G. D. D.; Durbin, R.; Martin, S. H.; Jiggins, C. D.
10.1101/2023.03.24.533969 — genomics — Posted on 2023-07-26
721 The impact of the Turkish (TK) population variome on the genomic architecture of rare disease traits
Coban Akdemir, Z.; Song, X.; Ceballos, F. C.; Pehlivan, D.; Karaca, E.; Bayram, Y.; Mitani, T.; Gambin, T. L.; Bozkurt Yozgatli, T.; Jhangiani, S.; muzny, d. m.; Lewis, R.; Baylor Hopkins Center for Mendelian Genomics, ; Liu, P.; Boerwinkle, E.; Hamosh, A.; Gibbs, R. A.; Sutton, R.; Sobreira, N.; Carvalho, C. M. B.; Shaw, C. A.; Posey, J.; Valle, D.; Lupski, J. R.
10.1101/2020.04.27.064824 — genomics — Posted on 2023-07-26
724 Functional interaction of torsinA and its activators in liver lipid metabolism
Hernandez-Ono, A.; Zhao, Y. P.; Murray, J. W.; Ostlund, C.; Lee, M. J.; Shi, A.; Dauer, W. T.; Worman, H. J.; Ginsberg, H. N.; Shin, J.-Y.
10.1101/2023.06.21.545957 — cell biology — Posted on 2023-07-27
725 Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
Luo, Y.; Hao, H.; Wang, Z.; Ong, C.; Dutcher, R.; Xu, Y.; Liu, J.; Pedersen, L. C.; Xu, D.
10.1101/2023.07.26.550758 — cell biology — Posted on 2023-07-27
729 A functional microbiome catalog crowdsourced from North American rivers
Borton, M. A.; McGivern, B. B.; Willi, K. R.; Woodcroft, B. J.; Mosier, A. C.; Singleton, D. M.; Bambakidis, T.; Pelly, A. C.; Liu, F.; Edirisinghe, J. N.; Faria, J. P.; Leleiwi, I.; Daly, R. A.; Goldman, A. E.; Wilkins, M. J.; Hall, E.; Pennacchio, C.; Roux, S.; Eloe-Fadrosh, E. A.; Good, S. P.; Sullivan, M. B.; Henry, C. S.; Wood-Charlson, E. M.; Ross, M. R.; Miller, C. S.; Crump, B. C.; Stegen, J.; Wrighton, K. C.
10.1101/2023.07.22.550117 — microbiology — Posted on 2023-07-26
730 Ultra-high field fMRI of visual mental imagery in typical imagers and aphantasic individuals
Liu, J.; Zhan, M.; Hajhajate, D.; Spagna, A.; Dehaene, S.; Cohen, L.; Bartolomeo, P.
10.1101/2023.06.14.544909 — neuroscience — Posted on 2023-07-26
731 Synaptic and dendritic architecture of two types of hippocampal somatostatin interneurons
Takacs, V.; Bardoczi, Z.; Orosz, A.; Major, A.; Tar, L.; Berki, P.; Papp, P.; Mayer, M. I.; Zsolt, L.; Sos, K. E.; Kali, S.; Freund, T. F.; Nyiri, G.
10.1101/2023.05.14.540675 — neuroscience — Posted on 2023-07-26
732 Sodium channel endocytosis drives axon initial segment plasticity
FREAL, A.; Jamann, N.; Ten Bos, J.; Jansen, J.; Petersen, N.; Ligthart, T.; Hoogenraad, C.; Kole, M. H. P.
10.1101/2022.11.09.515770 — neuroscience — Posted on 2023-07-26
736 Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
Wollman, A. J.; Syeda, A.; Howard, J.; Payne-Dwyer, A.; Leech, A.; Guy, C.; McGlynn, P.; Hawkins, M.; Leake, M. C.
10.1101/2021.02.22.432310 — biophysics — Posted on 2023-07-26
737 Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter
Tang, Q.; Sinclair, M.; Hasdemir, H. S.; Stein, R. A.; Karakas, E.; Tajkhorshid, E.; Mchaourab, H.
10.1101/2023.05.29.541986 — biophysics — Posted on 2023-07-26
738 A Molecular Communication model for cellular metabolism
Sakkaff, Z.; Freiburger, A.; Catlett, J. L.; Cashman, M.; Immaneni, A.; Buan, N. R.; Cohen, M.; Henry, C.; Pierobon, M.
10.1101/2023.06.28.546976 — bioinformatics — Posted on 2023-07-26
739 Stimulated Raman Photothermal Microscopy towards Ultrasensitive Chemical Imaging
Zhu, Y.; Ge, X.; Ni, H.; Yin, J.; Lin, H.; Wang, L.; Tan, Y.; Prabhu Dessai, C. V.; Li, Y.; Teng, X.; Cheng, J.-X.
10.1101/2023.03.06.531387 — bioengineering — Posted on 2023-07-26
741 Deep convolutional and conditional neural networks for large-scale genomic data generation
Yelmen, B.; Decelle, A.; Boulos, L. L.; Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Jay, F.
10.1101/2023.03.07.530442 — genomics — Posted on 2023-07-26
746 Cell type-specific control of secondary cell wall formation by Musashi-type translational regulators in Arabidopsis
Kairouani, A.; Pontier, D.; Picart, C.; Mounet, F.; Martinez, Y.; Le-Bot, L.; Fanuel, M.; Hammann, P.; Belmudes, L.; Merret, R.; Azevedo, J.; Carpentier, M.-C.; Gagliardi, D.; Coute, Y.; Sibout, R.; Bies-Etheve, N.; LAGRANGE, T.
10.1101/2023.03.20.532888 — plant biology — Posted on 2023-07-26
747 Genome assembly reconstruction of the Japanese honey bee, Apis cerana japonica (Hymenoptera: Apidae), using homology-based assembly and nanopore long-reads
Masuoka, Y.; Jouraku, A.; Kuwazaki, S.; Yoshiyama, M.; Horigane-Ogihara, M.; Maeda, T.; Suzuki, Y.; Bono, H.; Kimura, K.; Yokoi, K.
10.1101/2023.07.26.550500 — genomics — Posted on 2023-07-26
751 DNA methylation insulates genic regions from CTCF loops near nuclear speckles
Roseman, S. A.; Siegenfeld, A. P.; Lee, C.; Lue, N. Z.; Waterbury, A. L.; Liau, B. B.
10.1101/2023.07.26.550645 — genomics — Posted on 2023-07-26
752 Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures
Hisey, J. A.; Radchenko, E. A.; Ceschi, S.; Rastokina, A.; Mandel, N. H.; McGinty, R. J.; Matos-Rodrigues, G.; Hernandez, A.; Nussenzweig, A.; Mirkin, S. M.
10.1101/2023.07.25.550509 — genetics — Posted on 2023-07-26
755 Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants
McDonnell, A. F.; Plech, M.; Livesey, B. J.; Gerasimavicius, L.; Owen, L. J.; Hall, H. N.; FitzPatrick, D. R.; Marsh, J. A.; Kudla, G.
10.1101/2023.07.25.550478 — genetics — Posted on 2023-07-26
758 The Feather Epithelium Contributes to the Dissemination and Ecology of clade 2.3.4.4b H5 High Pathogenicity Avian Influenza Virus in Ducks
Gaide, N.; Filaire, F.; Bertran, K.; Crispo, M.; Dirat, M.; Secula, A.; Foret-Lucas, C.; Payre, B.; Perlas, A.; Cantero, G.; Majo, N.; Soubies, S.; GUERIN, J.-L.
10.1101/2023.07.26.550633 — microbiology — Posted on 2023-07-26
759 The capsular polysaccharide obstructs wall teichoic acid functions in Staphylococcus aureus
Lehmann, E.; van Dalen, R.; Gritsch, L.; Slavetinsky, C. J.; Korn, N.; Rohmer, C.; Krause, D.; Peschel, A.; Weidenmaier, C.; Wolz, C.
10.1101/2023.07.26.550747 — microbiology — Posted on 2023-07-26
760 Genes associated with fitness and disease severity in the pan-genome of mastitis-associated Escherichia coli
Olson, M. A.; Cullimore, C.; Hutchison, W. D.; Grimsrud, A.; Nobrega, D.; Barkema, H. W.; De Buck, J.; Pickett, B. E.; Wilson, E.; Erickson, D. L.
10.1101/2023.07.26.549771 — microbiology — Posted on 2023-07-26
761 Electrobiocorrosion by Microbes without Outer-Surface Cytochromes
Holmes, D. E.; Woodard, T. L.; Smith, J. A.; Musat, F.; Lovley, D. R.
10.1101/2023.07.26.550717 — microbiology — Posted on 2023-07-26
765 Benchmarking DNA Isolation Methods for Marine Metagenomics Studies
Isaev, A.; Demkina, A.; Slonova, D.; Mamontov, V.; Konovalova, O.; Yurikova, D.; Rogozhin, V.; Belova, V.; Korostin, D.; Sutormin, D.; Severinov, K. V.
10.1101/2023.07.25.550485 — bioinformatics — Posted on 2023-07-26
766 A practical and robust method to evaluate metabolic fluxes in pancreatic islets
Rocha, D. S.; Manucci, A. C.; Bruni-Cardoso, A.; Kowaltowski, A. J.; Vilas-Boas, E. A.
10.1101/2023.07.25.550538 — biochemistry — Posted on 2023-07-26
769 An allelic series at the EDNRB2 locus controls diverse piebalding patterns in the domestic pigeon
Maclary, E. T.; Wauer, R.; Phillips, B.; Brown, A.; Boer, E. F.; Samani, A. M.; Shapiro, M.
10.1101/2023.07.26.550625 — genetics — Posted on 2023-07-26
771 Sources of prey availability data alter interpretation of outputs from prey choice null networks
Cuff, J. P.; Tercel, M. P.; Windsor, F. M.; Hawthorne, B. S.; Hamback, P. A.; Bell, J. R.; Symondson, W. O.; Vaughan, I. P.
10.1101/2023.07.25.549927 — ecology — Posted on 2023-07-26
774 Macrophage inhibitor clodronate enhances liver transduction of lentiviral but not AAV vectors or mRNA lipid nanoparticles in vivo.
Touramanidou, L.; Gurung, S.; Cozmescu, C. A.; Perocheau, D. P.; Moulding, D.; Ridout, D.; Cavedon, A.; Siddiqui, S.; Rice, L.; Finn, P. F.; Martini, P. G. V.; Frassetto, A.; Waddington, S. N.; Counsell, J. R.; Gissen, P.; Baruteau, J.
10.1101/2023.07.26.550697 — molecular biology — Posted on 2023-07-26
776 Biofilm formation in Zymoseptoria tritici
Tyzack, T. E.; Hacker, C.; Thomas, G.; Fones, H. N.
10.1101/2023.07.26.550639 — microbiology — Posted on 2023-07-26
779 BacScan: An Unbiased and Genome-Wide Approach to Identify Bacterial Highly Immunogenic Proteins
Tao, P.; Dong, J.; Zhang, Q.; Yang, J.; Zhao, Y.; Miao, Z.; Pei, S.; Qin, H.; Wen, G.; Zhang, A.
10.1101/2023.07.26.550668 — microbiology — Posted on 2023-07-26
782 Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions
Pierre, C. N.; Adams, L. E.; Anasti, K.; Goodman, D.; Stanfield-Oakley, S.; Powers, J. M.; Li, D.; Rountree, W.; Wang, Y.; Edwards, R. J.; Alam, S. M.; Ferrari, G.; Tomaras, G. D.; Haynes, B. F.; Baric, R. S.; Saunders, K.
10.1101/2023.07.25.550460 — immunology — Posted on 2023-07-26
783 Multi-region spatial transcriptome analysis reveals cellular networks and pathways associated with hepatocellular carcinoma recurrence
Aiderus, A.; Seshachalam, P. V.; Idzham, K.; Caldez, M.; Shanmugam, R.; Sari, I. N.; Ying, D. H. H.; Chong, S. L.; Sekar, K.; Chew, S. C.; Chen, G. B.; Chung, A. Y.-F.; Cheow, P. C.; Kam, J. H.; Koh, A. W.-C.; Ganpathi, I. S.; Loong, S.; Leow, W.-Q.; Chen, K.; Chanwat, R.; de Villa, V. H.; Koh, P. S.; Bonney, G. K.; Goh, B. K. P.; Tam, W. L.; Tergaonkar, V.; Chow, P. K. H.
10.1101/2023.07.26.549242 — cancer biology — Posted on 2023-07-26
787 The maintenance of centriole appendages and motile cilia basal body anchoring relies on TBCCD1
Carmona, B.; Camelo, C.; Mehraz, M.; Lemullois, M.; Lince-Faria, M.; Coyaud, E.; Marinho, H. S.; Goncalves, J.; Nolasco, S.; Pinto, F.; Raught, B.; Tassin, A.-M.; Koll, F.; Soares, H.
10.1101/2023.07.26.549647 — cell biology — Posted on 2023-07-26
791 γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids
Dong, J.; Holthaus, D.; Peters, C.; Koster, S.; Ehsani, M.; Quevedo-Olmos, A.; Berger, H.; Zarobkiewicz, M.; Mangler, M.; Kumar Gurumurthy, R.; Hedemann, N.; Chumduri, C.; Kabelitz, D.; Meyer, T. F.
10.1101/2023.07.25.550464 — immunology — Posted on 2023-07-26
794 The mouse dorsal peduncular cortex encodes fear memory
Campos-Cardoso, R.; Desa, Z.; Fitzgerald, B.; Moore, A.; Duhon, J.; Landar, V.; Clem, R.; Cummings, K. A.
10.1101/2023.07.24.550408 — neuroscience — Posted on 2023-07-26
796 Identifying novel links between cardiovascular disease and insomnia by Drosophila modeling of genes from a pleiotropic GWAS locus
Melkani, G. C.; Abou Daya, F.; Ober, L.; Patel, D.; Mandigo, T.; Maher, M.; Tchio, C.; Walker, J. A.; Saxena, R.
10.1101/2023.07.24.550429 — physiology — Posted on 2023-07-26
797 EPINEST, an agent-based model to simulate epidemic dynamics in large-scale poultry production and distribution networks
Pinotti, F.; Lourenco, J.; Gupta, S.; Das Gupta, S.; Henning, J.; Blake, D.; Tomley, F.; Barnett, T.; Pfeiffer, D.; Hoque, M. A.; Fournie, G.
10.1101/2023.07.25.550458 — bioinformatics — Posted on 2023-07-26
800 A genomic exploration of the possible de-extirpation of the Zanzibar leopard
Sun, X.; Cavill, E. L.; Margaryan, A.; Lin, J.; Thingaard, S.; Said, T. A.; Gopalakrishnan, S.; Gilbert, M. T. P.
10.1101/2023.07.25.550323 — evolutionary biology — Posted on 2023-07-26
802 Characterization of trade-offs between immunity and reproduction in Astrangia poculata
Villafranca, N.; Changsut, I.; Diaz de Villegas, S. C.; Womack, H. R.; Fuess, L. E.
10.1101/2023.07.24.550370 — immunology — Posted on 2023-07-26
803 Sympathetic NPY controls glucose homeostasis, cold tolerance, and cardiovascular functions in mice
Kumari, R.; Pascalau, R.; Wang, H.; Bajpayi, S.; Yurgel, M.; Quansah, K.; Hattar, S.; Tampakakis, E.; Kuruvilla, R.
10.1101/2023.07.24.550381 — neuroscience — Posted on 2023-07-26
810 A Novel Milli-fluidic Liver Tissue Chip with continuous Recirculation for Predictive pharmacokinetics Applications
Rajan, S. A. P.; Sherfey, J.; Ohri, S.; Nichols, L.; Smith, J. T.; Parekh, P.; Kadar, E. P.; Clark, F.; George, B. T.; Gregory, L.; Tess, D.; Gosset, J. R.; Liras, J.; Geishecker, E.; Obach, R. S.; Cirit, M.
10.1101/2023.07.24.550337 — pharmacology and toxicology — Posted on 2023-07-26
811 PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation
Du, C.; Dong, J.; Xu, C.; Jia, P.; Cai, N.; Wang, Q.; Zhang, Z.; Jiang, L.; Jiang, W.; Feng, R.; Li, J.; Huang, C.; Ma, T.
10.1101/2023.07.24.550330 — pharmacology and toxicology — Posted on 2023-07-26
812 Discovery of fibrotic intervertebral disc in mice
He, J.; Huang, S.; Yan, P.; Li, Y.; Jin, H.; Hu, O.; Zhu, J.; Lin, P.; Wang, Y.; Zhang, L.; Guo, Y.; Wang, L.; Zhao, J.; Xie, Y.; Chen, L.; Lan, Y.; Liu, B.; Liu, P.; Gan, Y.
10.1101/2023.07.24.550303 — pathology — Posted on 2023-07-26
813 Direct reprogramming of oral epithelial progenitor cells to cancer stem cells at single cell resolution in vivo
Faraji, F.; Ramirez, S. I.; Clubb, L.; Sato, K.; Anguiano Quiroz, P. Y.; Galloway, W. M.; Mikulski, Z.; Hoang, T. S.; Medetgul-Ernar, K.; Marangoni, P.; Jones, K. B.; Officer, A.; Molinolo, A. A.; Kim, K.; Sakaguchi, K.; Califano, J. A.; Smith, Q.; Klein, O. D.; Tamayo, P.; Gutkind, J. S.
10.1101/2023.07.24.550427 — cancer biology — Posted on 2023-07-26
818 Massively Concurrent Sub-Cellular Traction Force Videography enabled by Single-Pixel Optical Tracers (SPOTs)
Tan, X. H. M.; Wang, Y.; Zhu, X.; Mendes, F. N.; Chung, P.-S.; Chow, Y. T.; Man, T.; Lan, H.; Lin, Y.-J.; Zhang, X.; Zhang, X.; Nguyen, T.; Ardehali, R.; Teitell, M. A.; Deb, A.; Chiou, P.-Y.
10.1101/2023.07.25.550454 — bioengineering — Posted on 2023-07-26
820 The influence of HLA genetic variation on plasma protein expression
Krishna, C.; Chiou, J.; Lee, I.; Kim, H. I.; Atalar Aksit, M.; Sakaue, S.; Von Schack, D.; Raychaudhuri, S.; Ziemek, D.; Hu, X.
10.1101/2023.07.24.550394 — genetics — Posted on 2023-07-26
827 Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations
Fenton, T.; Haouchine, O.; Hallam, E.; Smith, E.; Jackson, K.; Rahbarian, D.; Canales, C. P.; Adhikari, A.; Nord, A. S.; Ben-Shalom, R.; Silverman, J. L.
10.1101/2023.07.24.550093 — neuroscience — Posted on 2023-07-26
833 A heterozygous CEBPA mutation disrupting the bZIP domain causes MDS disease progression
Almaghrabi, R.; Alyayhawi, Y.; Keane, P.; Ward, C. R. J.; Bayley, R.; Sargas, C.; Menendez, P.; Murphy, G. J.; Sobahy, T.; Baghdadi, M. A.; Flemban, A. F.; Kabrah, S.; Akerman, I.; Raghavan, M.; Barragan, E.; Bonifer, C.; Garcia, P.
10.1101/2023.07.24.550349 — cancer biology — Posted on 2023-07-26
834 Disease-specific tau filaments assemble via polymorphic intermediates
Lövestam, S.; Li, D.; Wagstaff, J. L.; Kotecha, A.; Kimanius, D.; McLaughlin, S. H.; Murzin, A. G.; Freund, S. M. V.; Goedert, M.; Scheres, S. H. W.
10.1101/2023.07.24.550295 — biophysics — Posted on 2023-07-26
836 Physical Chemistry of Drug Permeation through the Cell Membrane with Atomistic Detail
Paulikat, M.; Piccini, G.; Ippoliti, E.; Rossetti, G.; Arnesano, F.; Carloni, P.
10.1101/2023.07.24.550356 — biophysics — Posted on 2023-07-26
837 Structural Coverage of the Human Interactome
Kosoglu, K.; Aydin, Z.; Keskin, O.; Tuncbag, N.; Gursoy, A.
10.1101/2023.07.24.550328 — bioinformatics — Posted on 2023-07-26
839 Data-driven probabilistic definition of the low energy conformational states of protein residues
Gavalda-Garcia, J.; Bickel, D.; Roca-Martinez, J.; Raimondi, D.; Orlando, G.; Vranken, W. F.
10.1101/2023.07.24.550386 — bioinformatics — Posted on 2023-07-26
842 Single-cell precision nanotechnology in vivo
MOLBAY, M.; Kick, B.; Zhao, S.; Todorov, M. I.; Ohn, T.-L.; Roth, S.; Simats, A.; Singh, V.; Khalin, I.; Pan, C.; Singh Bhatia, H.; Hellal, F.; Zeidler, R.; Liesz, A.; Plesnila, N.; Dietz, H.; Erturk, A.
10.1101/2023.07.24.550304 — bioengineering — Posted on 2023-07-26
849 Protein Assembly Modulation: A New Approach to ALS Therapeutics
Yu, S. F.; Paulvannan, K.; Solas, D.; Lingappa, A. F.; Moreira, A. R.; Sahu, S.; Michon, M.; Goldsmith, D.; DeYarman, N.; Mallesh, S.; Prasad, M. D.; Maios, C.; Ruan, K.; Tomassy, G. S.; Jensen, E.; McGuirk, E.; Bader, V.; Meuller-Schiffmann, A.; Reed, J. C.; Lingappa, J. R.; Asundi, V.; Hong, S.; Jacobsen, S.; Ostrow, L.; Lloyd, T.; Parker, A. E.; Staats, K. A.; Ichida, J.; Dodge, J.; Dey, D.; Korth, C.; Selvarajah, S.; Lingappa, V. R.; Rosenfeld, J.
10.1101/2023.07.24.550252 — neuroscience — Posted on 2023-07-26
850 Microglia Regulate Sleep via Calcium-Dependent Modulation of Norepinephrine Transmission
Ma, C.; Li, B.; Silverman, D.; Ding, X.; Li, A.; Xiao, C.; Huang, G.; Worden, K.; Muroy, S.; Chen, W.; Xu, Z.; Tso, C. F.; Huang, Y.; Zhang, Y.; Luo, Q.; Saijo, K.; Dan, Y.
10.1101/2023.07.24.550176 — neuroscience — Posted on 2023-07-26
851 Denoising Diffusion MRI: Considerations and implications for analysis
Patron, J. P. M.; Moeller, S.; Yacoub, E.; Andersson, J. L. R.; Sotiropoulos, S. N.
10.1101/2023.07.24.550348 — neuroscience — Posted on 2023-07-26
853 Coding dynamics of the striatal networks during learning
Villet, M.; Reynaud-Bouret, P.; Poitreau, J.; Baldi, J.; Jaffard, S.; James, A.; Muzy, A.; Sargolini, F.; Bethus, I.
10.1101/2023.07.24.550305 — neuroscience — Posted on 2023-07-26
854 Lipidomic analysis reveals differences in the extent of remyelination in the brain and spinal cord
Mohotti, N. D. S.; Kobayashi, H.; Williams, J. M.; Binjawadagi, R.; Evertsen, M. P.; Christ, E. G.; Hartley, M. D.
10.1101/2023.07.24.550351 — neuroscience — Posted on 2023-07-26
857 Microglial cannabinoid receptor type1 mediates social memory deficits produced by adolescent THC exposure and 16p11.2 duplication
Hasegawa, Y.; Kim, J.; Ursini, G.; Jouroukhin, Y.; Zhu, X.; Miyahara, Y.; Xiong, F.; Madireddy, S.; Obayashi, M.; Lutz, B.; Sawa, A.; Brown, S. P.; Pletnikov, M. V.; Kamiya, A.
10.1101/2023.07.24.550212 — neuroscience — Posted on 2023-07-26
858 Impaired cholesterol transport from aged astrocytes to neurons can be rescued by cannabinoids.
Allende, L. G.; Natali, L.; Cragnolini, A. B.; Musri, M. M.; de Mendoza, D.; Martin, M. G.
10.1101/2023.07.24.550299 — neuroscience — Posted on 2023-07-26
861 ERBB signalling contributes to immune evasion in KRAS-driven lung adenocarcinoma
Laing, S.; Kruspig, B.; Shaw, R.; Officer-Jones, L.; Edwards, S.; McKinven, D.; Hsieh, Y.-C.; Powley, I.; Brady, N.; Pennie, R.; Kwan, R.; Lima, A.; Myrta, S.; Periyasamy, M.; Dye, I. C.; Nixon, C.; Clark, G.; Junttila, M. R.; Maddalo, D.; Miller, C.; Ali, S.; Fuchter, M. J.; Nickles, D.; Kirschner, K.; Brown, R. B.; LeQuesne, J.; Strathdee, D.; Coffelt, S. B.; Roberts, E.; Murphy, D. J.
10.1101/2023.07.24.550274 — cancer biology — Posted on 2023-07-26
862 Discovering genetic biomarkers for targeted cancer therapeutics with eXplainable AI
Chakraborty, D.; Gutierrez-Chakraborty, E. P.; Rodriguez-Aguayo, C.; Basagaoglu, H.; Lopez-Berestein, G.; Amero, P.
10.1101/2023.07.24.550346 — bioinformatics — Posted on 2023-07-26
864 Copy Number Variants and heritability estimates on UKBiobank data
Boulahfa, J.; Le Floch, E.; Pierre-Jean, M.; Deleuze, J.-F.; Dandine-Roulland, C.
10.1101/2023.07.24.550287 — genetics — Posted on 2023-07-26
866 Venom tradeoff shapes interspecific interactions, physiology and reproduction
Surm, J. M.; Birch, S. J.; Macrander, J.; Jaimes-Becerra, A.; Fridrich, A.; Aharoni, R.; Rozenblat, R.; Sharabany, J.; Appelbaum, L.; Reitzel, A. M.; Moran, Y.
10.1101/2023.07.24.550294 — evolutionary biology — Posted on 2023-07-26
871 Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease
Miyoshi, E.; Morabito, S.; Henningfield, C. M.; Rahimzadeh, N.; Shabestari, S. K.; Das, S.; Michael, N.; Reese, F.; Shi, Z.; Cao, Z.; Scarfone, V.; Arreola, M. A.; Lu, J.; Wright, S.; Silva, J.; Leavy, K.; Lott, I. T.; Doran, E.; Yong, W. H.; Shahin, S.; Perez-Rosendahl, M.; Head, E.; Green, K. N.; Swarup, V.
10.1101/2023.07.24.550282 — neuroscience — Posted on 2023-07-26
872 Lariat debranching by RNA DEBRANCHING ENZYME 1 depends on SICKLE in Arabidopsis thaliana
Kovak, E. E.; Marshall, C. M.; Molinari, M. D. C.; Nepomuceno, A. L.; Harmon, F. G.
10.1101/2023.07.25.550414 — molecular biology — Posted on 2023-07-26
875 Same same but different; The global response of Escherichia coli to five different LpxC inhibitors
Moller, A. M.; Vazquez Hernandez, M.; Kutscher, B.; Brysch, R.; Bruckner, S.; Marino, E. C.; Kleetz, J.; Senges, C. H. R.; Schakermann, S.; Bandow, J. E.; Narberhaus, F.
10.1101/2023.07.25.550486 — microbiology — Posted on 2023-07-26
876 Elevated peripheral and nervous system inflammation is associated with decreased short-chain fatty acid levels in Zika-virus infected macaques
Miller, C.; Manuzak, J.; Gustin, A.; Basting, C.; Cheu, R.; Schroeder, T.; Velez, A.; Driscoll, C.; Tisoncik-Go, J.; Schifanella, L.; Hensley-McBain, T.; Evandy, C.; Smith, E.; Bratt, D.; Smedley, J.; O'Connor, M.; Fuller, D.; Barouch, D.; Gale, M.; Klatt, N. R.
10.1101/2023.07.25.550459 — microbiology — Posted on 2023-07-26
880 Balancing grain yield trade-offs in 'Miracle-Wheat'
Abbai, R.; Golan, G.; Longin, C. F. H.; Schnurbusch, T.
10.1101/2023.02.23.529729 — plant biology — Posted on 2023-07-26
881 Histone variant H2A.Z is required for plant salt response by regulating gene transcription
Miao, R.; Zhang, Y.; Liu, X.; Yuan, Y.; Zang, W.; Li, Z.; Yan, X.; Pang, Q.; Zhang, A.
10.1101/2023.07.26.550612 — plant biology — Posted on 2023-07-26
885 Predicting response to cytotoxic chemotherapy
Thompson, J.; Madrid, L.; Hernando, B.; Sauer, C.; Vias, M.; Escobar-Rey, M.; Leung, W.-K.; Huckstep, J.; Sekowska, M.; Hosking, K.; Jimenez-Linan, M.; Reinius, M.; Dobson, H.; De Silva, D.; Fernandez-Sanroman, A.; Sanders, D.; Correia Martins, F.; Quintela-Fandino, M.; Markowetz, F.; Yip, J.; Brenton, J. D.; Piskorz, A.; Macintyre, G.
10.1101/2023.01.28.525988 — cancer biology — Posted on 2023-07-26
886 Cell Surface β-Lactamase Recruitment: A Facile Selection to Identify Protein-Protein Interactions
McNaughton, B.; Hinmon, J.; King, J.; Mayo, L.; Faries, C.; Street, Y.; Crawford, D.; Beardslee, P.; Hendricks, A.
10.1101/2023.07.23.550224 — biochemistry — Posted on 2023-07-26
889 Non-Hebbian plasticity transforms transient experiences into lasting memories
Faress, I.; Khalil, V.; Hou, W.-H.; Moreno, A.; Andersen, N.; Fonseca, R.; Piriz, J.; Capogna, M.; Nabavi, S.
10.1101/2023.04.06.535862 — neuroscience — Posted on 2023-07-26
890 Metamodelling of a two-population spiking neural network
Skaar, J.-E. W.; Haug, N.; Stasik, A. J.; Plesser, H. E.; Einevoll, G. T.; Tondel, K.
10.1101/2022.09.05.506616 — neuroscience — Posted on 2023-07-26
893 Host interactions of novel Crassvirales species belonging to multiple families infecting bacterial host, Bacteroides cellulosilyticus WH2
Papudeshi, B.; Vega, A. A.; Souza, C.; Giles, S. K.; Mallawaarachchi, V.; Roach, M. J.; An, M.; Jacobson, N.; McNair, K.; Mora, M. F.; Pastrana, K.; Boling, L.; Leigh, C.; Cram, C.; Plewa, W. S.; Grigson, S. R.; Bouras, G.; Decewicz, P.; Luque, A.; Droit, L.; Handley, S. A.; Wang, D.; Segall, A.; Dinsdale, E. A.; Edwards, R. A.
10.1101/2023.03.05.531146 — bioinformatics — Posted on 2023-07-26
894 Quantifying microbial guilds
Rivas-Santisteban, J.; Yubero, P.; Robaina-Estevez, S.; Gonzalez, J. M.; Tamames, J.; Pedros-Alio, C.
10.1101/2023.07.23.550202 — ecology — Posted on 2023-07-26
896 Changes in biodiversity impact atmospheric chemistry and climate through plant volatiles and particles
Sanaei, A.; Herrmann, H.; Alshaabi, L.; Beck, J.; Ferlian, O.; Wadinga Fomba, K.; Haferkorn, S.; van Pinxteren, M.; Quaas, J.; Quosh, J.; Rabe, R.; Wirth, C.; Eisenhauer, N.; Weigelt, A.
10.1101/2023.01.28.526055 — ecology — Posted on 2023-07-26
897 Cobalt-sulfur coordination chemistry drives B12 loading onto methionine synthase
Mascarenhas, R.; Guha, A.; Li, Z.; Ruetz, M.; An, S.; Seravalli, J.; Banerjee, R.
10.1101/2023.07.25.550549 — biochemistry — Posted on 2023-07-26
898 Collective dynamics of formin and microtubule and its crosstalk mediated by FHDC1
Tong, C. S.; Su, M.; Sun, H.; Chua, X. L.; Guo, S.; Ramaraj, R. S.; Lee, A. G.; Ong, N. W. P.; Miao, Y.; Wu, M.
10.1101/2023.07.25.550329 — cell biology — Posted on 2023-07-25
899 Mechano-dependent sorbitol accumulation supports biomolecular condensate
Torrino, S.; Oldham, W.; Tejedor, A. R.; Sanchez-Burgos, I.; Rachedi, N.; Fraissard, K.; Chauvet, C.; Sbai, C.; O'Hara, B. P.; Abelanet, S.; Brau, F.; Clavel, S.; Collepardo-Guevara, R.; Rene Espinosa, J.; ben-sahra, I.; BERTERO, T.
10.1101/2023.07.24.550444 — cell biology — Posted on 2023-07-25
900 pHusion: A robust and versatile toolset for automated detection and analysis of exocytosis
O'Shaughnessy, E. C.; Lam, M.; Ryken, S. E.; Wiesner, T.; Lukasik, K.; Zuchero, J. B.; Leterrier, C.; Adalsteinsson, D.; Gupton, S. L.
10.1101/2023.07.25.550499 — cell biology — Posted on 2023-07-25
901 TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells
Ceglowski, J.; Hoffman, H. K.; Hoff, K. J.; McCurdy, B. L.; Moore, J.; Prekeris, R.
10.1101/2023.07.25.550533 — cell biology — Posted on 2023-07-25
904 FAM104 proteins promote the nuclear localization of p97/VCP
Körner, M.; Meyer, S.; Marincola, G.; Kern, M.; Grimm, C.; Schülein-Völk, C.; Fischer, U.; Hofmann, K.; Buchberger, A.
10.1101/2023.07.25.550451 — cell biology — Posted on 2023-07-25
906 Primary human lung fibroblasts exhibit trigger- but not disease-specific cellular senescence and impair alveolar epithelial cell progenitor function
Bramey, N.; Melo-Narvaez, M. C.; See, F.; Ballester-Llobell, B.; Steinchen, C.; Jain, E.; Hafner, K.; Yildirim, A. O.; Koenigshoff, M.; Lehmann, M.
10.1101/2023.07.24.550385 — cell biology — Posted on 2023-07-26
907 Leishmania major-induced alteration of host cellular and systemic copper homeostasis drives the fate of infection
Paul, R.; Chakrabarty, A.; Dey, S.; Samanta, S.; Pandey, R.; Maji, S.; Pezacki, A. T.; Chang, C. J.; Datta, R.; Gupta, A.
10.1101/2023.07.25.550461 — cell biology — Posted on 2023-07-26
908 VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
Mirsanaye, A. S.; Hoffmann, S.; Weisser, M. B.; Mund, A.; Lopez-Mendez, B.; Typas, D.; van den Boom, J.; Benedict, B.; Hendriks, I. A.; Nielsen, M. L.; Meyer, H.; Duxin, J. P.; Montoya, G.; Mailand, N.
10.1101/2023.07.25.550448 — molecular biology — Posted on 2023-07-25
909 Smart Leginon enables cryoEM screening automation across multiple grids
Sawh-Gopal, A.; Ishemgulova, A.; Chua, E. Y. D.; Aragon, M. F.; Mendez, J. H.; Eng, E. T.; Noble, A. J.
10.1101/2023.07.24.550406 — molecular biology — Posted on 2023-07-25
911 CURTAIN - A Unique Web-based tool for exploration and sharing of MS-based proteomics data
Phung, T. K.; Berndsen, K.; Phan, T. L.; Muqit, M. M.; Alessi, D. R.; Nirujogi, R. S.
10.1101/2023.07.25.550405 — systems biology — Posted on 2023-07-25
912 Gas vesicle-blood interactions enhance ultrasound imaging contrast
Ling, B.; Ko, J. H.; Stordy, B.; Zhang, Y.; Didden, T. F.; Malounda, D.; Swift, M. B.; Chan, W. C. W.; Shapiro, M. G.
10.1101/2023.07.24.550434 — synthetic biology — Posted on 2023-07-25
914 CRUX, a platform for visualising, exploring and analysing cancer genome cohort data
El-Kamand, S.; Quinn, J. M.; Sareen, H.; Becker, T. M.; Wong-Erasmus, M.; Cowley, M. J.
10.1101/2023.07.25.550585 — bioinformatics — Posted on 2023-07-25
915 Dynamics of Collagen Oxidation and Cross Linking in Regenerating and Irreversibly Infarcted Myocardium
Akam, E. A.; Bergemann, D.; Ridley, S. J.; To, S.; Andrea, B.; Moon, B.; Ma, H.; Zhou, Y.; Aguirre, A.; Caravan, P.; Gonzalez-Rosa, J. M.; Sosnovik, D. E.
10.1101/2023.07.25.549713 — biochemistry — Posted on 2023-07-25
916 Shared Structural Features of Miro Binding Control Mitochondrial Homeostasis
Covill-Cooke, C.; Kwizera, B.; Lopez-Domenech, G.; Thompson, C. O. D.; Cheung, N. J.; Cerezo, E.; Peterka, M.; Kittler, J. T.; Kornmann, B.
10.1101/2023.07.25.550462 — biochemistry — Posted on 2023-07-25
917 Competitive Microarray Screening Reveals Functional Ligands for the DHX15 RNA G-quadruplex
Prestwood, P. R.; Yang, M.; Lewis, G. V.; Balaratnam, S.; Yazdani, K.; Schneekloth, J. S.
10.1101/2023.07.25.550542 — biochemistry — Posted on 2023-07-25
918 Stress-induced vascular remodeling: novel insight into the role of omega-3 fatty acid metabolite, 4-oxoDHA
Nishimori, M.; Hayasaka, N.; Otsui, K.; Inoue, N.; Nagao, M.; Toh, R.; Ishida, T.; Hirata, K.; Furuyashiki, T.; Shinohara, M.
10.1101/2023.07.25.550603 — biochemistry — Posted on 2023-07-25
919 Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex
Dubiez, E.; Pellegrini, E.; Finderup Brask, M.; Garland, W.; Foucher, A.-E.; Huard, K.; Jensen, T. H.; Cusack, S.; Kadlec, J.
10.1101/2023.07.25.550453 — biochemistry — Posted on 2023-07-25
922 Redox-dependent condensation and cytoplasmic granulation by human ssDNA binding protein 1 delineate roles in oxidative stress response
Harami, G. M.; Palinkas, J.; Kovacs, Z. J.; Tarnok, K.; Harami-Papp, H.; Hegedus, J.; Mahmudova, L.; Kucsma, N.; Toth, S.; Szakacs, G.; Kovacs, M.
10.1101/2023.07.25.550517 — biochemistry — Posted on 2023-07-25
926 Systematic analysis of the sphingomyelin synthase family in C. elegans
Guzman, G. D.; Farley, S. E.; Kyle, J. E.; Bramer, L.; Hoeltzl, S.; van den Dikkenberg, J.; Holthuis, J. C. M.; Tafesse, F.
10.1101/2023.07.25.550547 — molecular biology — Posted on 2023-07-25
927 RNA and FUS act in concert to prevent TDP-43 spatial segregation
Demongin, C.; Tranier, S.; Joshi, V.; ceschi, l.; desforges, b.; pastre, d.; hamon, l.
10.1101/2023.07.25.550456 — molecular biology — Posted on 2023-07-25
929 Supercomputer framework for reverse engineering firing patterns of neuron populations to identify their synaptic inputs
Chardon, M. K.; Wang, Y. C.; Garcia, M.; Besler, E.; Beauchamp, J. A.; D'Mello, M.; Powers, R. K.; Heckman, C. J.
10.1101/2022.12.09.519818 — neuroscience — Posted on 2023-07-25
931 Comprehensive catalogs for microbial genes and metagenome-assembled genomes of the swine lower respiratory tract microbiome identify the relationship of microbial species with lung lesions
Li, J.; Huang, F.; Zhou, Y.; Huang, T.; Tong, X.; Zhang, M.; Chen, J.; Zhang, Z.; Du, H.; Liu, Z.; Zhou, M.; Xiahou, Y.; Ai, H.; Chen, C.; Huang, L.
10.1101/2023.07.25.550507 — microbiology — Posted on 2023-07-25
932 Pseudomonas aeruginosa AlgF is a protein-protein interaction mediator required for acetylation of the alginate exopolysaccharide
Low, K.; Gheorghita, A. A.; Tammam, S.; Whitfield, G. B.; Li, Y. E.; Riley, L. M.; Weadge, J.; Caldwell, S.; Chong, P. A.; Walvoort, M.; Kitova, E.; Klassen, J.; Howell, P. L.
10.1101/2023.07.25.550544 — microbiology — Posted on 2023-07-25
935 BRD4 directs mitotic cell division by inhibiting DNA damage
Wu, T.; Hou, H.; Dey, A.; Bachu, M.; Chen, X.; Wisniewski, J.; Kudoh, F.; Chen, C.; Chauhan, S.; Xiao, H.; Pan, R.; Ozato, K.
10.1101/2023.07.02.547436 — cell biology — Posted on 2023-07-25
936 Evolution and spread of a persistent P. aeruginosa outbreak clone over decades in a single US hospital.
Stribling, W.; Hall, L. R.; Powell, A.; Harless, C.; Martin, M. J.; Corey, B. W.; Snesrud, E.; Ong, A.; Maybank, R.; Stam, J.; Bartlett, K.; Jones, B. T.; Preston, L. N.; Lane, K. F.; Thompson, B.; Young, L. M.; Kwak, Y. I.; Barsoumian, A. E.; Markelz, A.-E.; Kiley, J. L.; Cybulski, R. J.; Bennett, J. W.; Mc Gann, P. T.; Lebreton, F.
10.1101/2023.07.24.550326 — microbiology — Posted on 2023-07-25
940 Mammalian cells-based platforms for the generation of SARS-CoV-2 virus-like particles
Elfayres, G.; Paswan, R. R.; Sika, L.; Girard, M.-P.; Khalfi, S.; Letanneur, C.; Milette, K.; Singh, A.; Kobinger, G.; Berthoux, L.
10.1101/2023.07.24.550415 — microbiology — Posted on 2023-07-25
941 Neighborhood air pollution is negatively associated with neurocognitive maturation in early adolescence
Kardan, O.; Sereeyothin, C.; Schertz, K. E.; Angstadt, M.; Weigard, A.; Berman, M. G.; Heitzeg, M. M.; Rosenberg, M. D.
10.1101/2023.04.28.538763 — neuroscience — Posted on 2023-07-25
942 Predictive Systems Biology Modeling: Unraveling Host Metabolic Disruptions and Potential Drug Targets in SARS-CoV-2 and Its Variants
Li, G.-H.; Han, F.; Luo, R.-H.; Li, P.; Chang, C.-J.; Xu, W.; Long, X.-Y.; Huang, J.-F.; Zheng, Y.-T.; Kong, Q.-P.; Xiao, W.
10.1101/2023.07.24.550423 — systems biology — Posted on 2023-07-25
944 Comparison of robotic automated and manual injection methods in zebrafish embryos for high throughput RNA silencing using CRISPR-CasRx
Abugattas-Nunez Del Prado, J.; Ding, Y.; de Sonneville, J.; van der Kolk, K.-J.; Moreno-Mateos, M. A.; Malaga-Trillo, E.; Spaink, H. P.
10.1101/2023.07.04.547651 — bioengineering — Posted on 2023-07-25
946 Mega-Enhancer Bodies Organize Neuronal Long Genes in the Cerebellum
Zhao, Z.; Parra, O. P.; Musella, F.; Scrutton-Alvarado, N.; Fujita, S.-i.; Alber, F.; Yang, Y.; Yamada, T.
10.1101/2023.07.19.549737 — neuroscience — Posted on 2023-07-25
947 Spatial extent of within-thalamus cortical connections varies across the cortical hierarchy in humans and macaques
Howell, A. M.; Warrington, S.; Fonteneau, C.; Cho, Y.; Sotiropoulos, S.; Murray, J. D.; Anticevic, A.
10.1101/2023.07.22.550168 — neuroscience — Posted on 2023-07-25
948 Odor cueing of declarative memories during sleep enhances coordinated spindles and slow oscillations
Sanchez-Corzo, A.; Baum, D. M.; Irani, M.; Hinrichs, S.; Reisenegger, R.; Whitaker, G. A.; Born, J.; Klinzing, J. G.; Sitaram, R.
10.1101/2023.02.10.527339 — neuroscience — Posted on 2023-07-25
950 Spatial Metabolome Lipidome and Glycome from a Single brain Section
Clarke, H. A.; Ma, X.; shedlock, c. J.; medina, t.; Hawkinson, T. R.; Wu, L.; Robas, R. A.; Ravi, S.; Bizon, J. L. L.; Burke, S. N.; Abisambra, J. F.; Merritt, M. E.; Prentice, B. M.; Vander Kooi, C. W.; Gentry, m. S.; Chen, L.; sun, r. c.
10.1101/2023.07.22.550155 — systems biology — Posted on 2023-07-25
951 Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension
Petrenko, O.; Koenigshofer, P.; Brusilovskaya, K.; Hofer, B. S.; Bareiner, K.; Simbrunner, B.; Trauner, M.; Kauschke, S. G.; Pfisterer, L.; Simon, E.; Rendeiro, A.; de Rooij, L.; Schwabl, P.; Reiberger, T.
10.1101/2023.07.22.550133 — systems biology — Posted on 2023-07-25
952 Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes
Khoo, A.; Govindarajan, M.; Qui, Z.; Liu, L. Y.; Ignatchenko, V.; Waas, M.; Macklin, A.; Keszei, A.; Main, B. P.; Yang, L.; Lance, R. S.; Downes, M. R.; Semmes, O. J.; Vesprini, D.; Liu, S. K.; Nyalwidhe, J. O.; Boutros, P. C.; Kislinger, T.
10.1101/2023.07.23.550214 — systems biology — Posted on 2023-07-25
953 CuticleTrace: A toolkit for capturing cell outlines of leaf cuticle with implications for paleoecology and paleoclimatology
Lloyd, B. A.; Barclay, R. S.; Dunn, R. E.; Currano, E. D.; Mohamaad, A. I.; Skersies, K.; Punyasena, S. W.
10.1101/2023.07.23.550217 — paleontology — Posted on 2023-07-25
955 METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma
Vaid, R.; Thombare, K.; Mendez, A.; Burgos-Panadero, R.; Djos, A.; Jachimowicz, D.; Ihrmark Lundberg, K.; Bartenhagen, C.; Kumar, N.; Tummler, C.; Sihlbom, C.; Fransson, S.; Johnsen, J. I.; Kogner, P.; Martinsson, T.; Fischer, M.; Mondal, T.
10.1101/2022.12.09.519591 — cancer biology — Posted on 2023-07-25
957 Using graph-based model to identify cell specific synthetic lethal effects
Pu, M.; Chen, K.; Li, X.; Xin, Y.; Wei, L.; Jin, S.; Zheng, W.; Peng, G.; Tang, Q.; Zhou, J.; Zhang, Y.
10.1101/2023.07.23.550246 — bioinformatics — Posted on 2023-07-25
958 Mechanotransduction governs CD40 function and underlies X-linked Hyper IgM syndrome
Choi, H.-K.; Travaglino, S.; Munchhalfen, M.; Gorg, R.; Zhong, Z.; Lyu, J.; Reyes-Aguilar, D. M.; Wienands, J.; Singh, A.; Zhu, C.
10.1101/2023.07.23.550231 — immunology — Posted on 2023-07-25
959 Conduction Velocity, G-ratio, and Extracellular Water as Microstructural Characteristics of Autism Spectrum Disorder
Newman, B. T.; Jacokes, Z.; Venkadesh, S. T.; Webb, S. J.; Kleinhans, N. M.; McPartland, J. C.; Druzgal, T. J.; Pelphrey, K. A.; Van Horn, J. D.; For the GENDAAR Research Consortium,
10.1101/2023.07.23.550166 — neuroscience — Posted on 2023-07-25
962 Entanglement of AGE-RAGE axis in cardiac pathosis
Wasim, R.; Mahmood, T.; Siddiqui, M. H.; Wani, T.; Zargar, S.; Singh, A.; Mohammed, S.; Ahsan, F.; Wahajuddin, M.
10.1101/2023.07.23.550244 — pharmacology and toxicology — Posted on 2023-07-25
970 Anti-CD47 immunotherapy as a therapeutic strategy for the treatment of breast cancer brain metastasis
Mackert, J. D.; Stirling, E. R.; Wilson, A. S.; Westwood, B.; Zhao, D.; Lo, H.-W.; Metheny-Barlow, L. J.; Cook, K. L.; Lesser, G. J.; Soto-Pantoja, D. R.
10.1101/2023.07.25.550566 — cancer biology — Posted on 2023-07-25
973 Sequential colonization events with restricted gene flow in a widespread European carnation species
Kazmareck, T.; Chen, X.; Fior, S.; Venon, A.; Roman, A.; Ursu, T.; Giraud, T.; Mezhenskyj, V.; Koupilova, K.; Hood, M.; Widmer, A.; Cornille, A.
10.1101/2023.07.23.550186 — evolutionary biology — Posted on 2023-07-25
974 Quantifying microbial guilds
Rivas-Santisteban, J.; Yubero, P.; Robaina-Estevez, S.; Gonzalez, J. M.; Tamames, J.; Pedros-Alio, C.
10.1101/2023.07.23.550202 — ecology — Posted on 2023-07-25
976 RAPID ALKALINIZATION FACTOR 22 is a key modulator of the proliferation and hyper-elongation responses of root hairs to microbial volatiles in Arabidopsis
Leon Morcillo, R. J.; Leal-Lopez, J.; Lopez-Serrano, L.; Baroja-Fernandez, E.; Gamez-Arcas, S.; G. Doblas, V.; Ferez-Gomez, A.; Pozueta-Romero, J.
10.1101/2023.07.20.549818 — plant biology — Posted on 2023-07-25
977 O-GlcNAcylation of Keratin 18 coordinates TCA cycle to promote cholangiocarcinoma progression
Xie, R.; Liu, J.; Wang, L.; Meng, X.; Zhou, Y.; Xu, L.; Wang, C.; Tian, X.; Zhang, X.; Hao, Y.; Cheng, B.
10.1101/2023.07.23.550247 — cancer biology — Posted on 2023-07-25
979 Imaging Giant Vesicle Membrane Domains with a Luminescent Europium Tetracycline Complex
Cawley, J. L.; Berger, B. A.; Odudimu, A. T.; Singh, A. N.; Santa, D. E.; McDarby, A. I.; Honerkamp-Smith, A. R.; Wittenberg, N. J.
10.1101/2022.07.01.498133 — biophysics — Posted on 2023-07-25
981 Deep learning-based cell profiling based on neuronal morphology
Liu, Q.; Nicholls, F. J.; Rowland, H. A.; Dangla-Valls, A.; Li, S.; Zhang, Y.; Kalinowski, P.; Ribe, E.; Ifkovits, J. L.; Kumar, S.; Nguyen, C. Q.; Holgado, A. N.; Buckley, N.; Kormilitzin, A.
10.1101/2023.07.23.550158 — bioinformatics — Posted on 2023-07-25
987 Whole-brain dynamics and hormonal fluctuations across the menstrual cycle: The role of progesterone and age in healthy women
Avila-Varela, D. S.; Hidalgo-Lopez, E.; Dagnino, P. C.; Acero-Pousa, I.; del Agua, E.; Deco, G.; Pletzer, B.; Escrichs, A.
10.1101/2023.07.23.550200 — neuroscience — Posted on 2023-07-25
989 Activation of the mevalonate pathway in response to anti-cancer treatments drives glioblastoma recurrences through activation of Rac-1
He, L.; Ioannidis, A.; Arambula, E.; Hoffman, C. J.; Joshi, P.; Kathiravan, A.; Whitelegge, J. P.; Liau, L. M.; Kornblum, H. I.; Pajonk, F.
10.1101/2023.07.23.550205 — neuroscience — Posted on 2023-07-25
990 Exploring the Role of MMP9 and its Interaction with TGFβ Signalling in Patients with Mesial Temporal Lobe Epilepsy-Hippocampal Sclerosis
Paul, D.; Srivastava, A.; Banerjee, J.; Tripathi, M.; Doddamani, R.; Lalwani, S.; Siraj, F.; Sharma, M. C.; Chandra, P. S.; Dixit, A.
10.1101/2023.07.22.550041 — neuroscience — Posted on 2023-07-25
993 ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
Rincon-Torroella, J.; Dal Molin, M.; Mog, B.; Han, G.; Watson, E.; Wyhs, N.; Ishiyama, S.; Ahmedna, T.; Minn, I.; Azad, N. S.; Bettegowda, C.; Papadopoulos, N.; Kinzler, K. W.; Zhou, S.; Vogelstein, B.; Gabrielson, K. L.; Sur, S.
10.1101/2023.07.23.550207 — cancer biology — Posted on 2023-07-25
995 ProstT5: Bilingual Language Model for Protein Sequence and Structure
Heinzinger, M.; Weissenow, K.; Sanchez, J. G.; Henkel, A.; Steinegger, M.; Rost, B.
10.1101/2023.07.23.550085 — bioinformatics — Posted on 2023-07-25
1001 Ocular dominance columns in mouse visual cortex
Goltstein, P. M.; Laubender, D.; Bonhoeffer, T.; Hübener, M.
10.1101/2023.07.22.550034 — neuroscience — Posted on 2023-07-25
1002 Prior probability cues bias sensory encoding with increasing task exposure
Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.
10.1101/2023.07.15.549123 — neuroscience — Posted on 2023-07-25
1003 Visuomotor experience induces functional and structural plasticity of chandelier cells
Seignette, K.; Jamann, N.; Papale, P.; Terra, H.; Porneso, R. P. O.; de Kraker, L.; van der Togt, C.; van der Aa, M.; Neering, P.; Ruimschotel, E.; Roelfsema, P. R.; Montijn, J. S.; Self, M. W.; Kole, M. H. P.; Levelt, C. N.
10.1101/2023.04.21.537780 — neuroscience — Posted on 2023-07-25
1004 Seed size control via phloem end by callose deposition/degradation of β-1,3-glucanase
Liu, X.; Nakajima, K. P.; Wu, X.; Zhu, S.; Adhikari, P. B.; Okada, K.; Kurotani, K.; Ishida, T.; Nakamura, M.; Sato, Y.; Xie, L.; Huang, C.; He, J.; Sawa, S.; Higashiyama, T.; Notaguchi, M.; Kasahara, R. D.
10.1101/2023.07.23.550179 — plant biology — Posted on 2023-07-25
1005 PIEZO1 force sensing controls global lipid homeostasis
Lichtenstein, L.; Cheng, C. W.; Evans, E. L.; Gaunt, H. J.; Bartoli, F.; Chuntharpursat-Bon, E.; Patel, S.; Konstantinou, C.; Futers, S.; Reay, M.; Parsonage, G.; Bertrand-Michel, J.; Sukumar, P.; Roberts, L. D.; Beech, D. J.
10.1101/2023.07.23.550198 — physiology — Posted on 2023-07-25
1006 Natural Product Screen Identifies Asiatic Acid Targeting Mutant p53
Swargiary, G.; Jamal, Q. M. S.; Ojha, S.; Jha, N. K.; Singh, K. K.; Mani, S.
10.1101/2023.07.23.550189 — cancer biology — Posted on 2023-07-25
1008 hadge: a comprehensive pipeline for donor deconvolution in single cell
Curion, F.; Wu, X.; Heumos, L.; Andre, M. G.; Halle, L.; Grant-Peters, M.; Rich-Griffin, C.; Yeung, H.-Y.; Dendrou, C. A.; Schiller, H. B.; Theis, F. J.
10.1101/2023.07.23.550061 — bioinformatics — Posted on 2023-07-25
1011 Repeated Caffeine Intake Suppresses Cerebral Grey Matter Responses to Chronic Sleep Restriction in an A1 Adenosine Receptor-Dependent Manner.
Lin, Y.-S.; Lange, D.; Baur, D.-M.; Foerges, A.; Chu, C.; Li, C.; Elmenhorst, E.-M.; Neumaier, B.; Bauer, A.; Aeschbach, D.; Landolt, H.-P.; Elmenhorst, D.
10.1101/2023.07.23.550201 — neuroscience — Posted on 2023-07-25
1015 Spatial patterns of within-thalamus anatomical connectivity vary across the cortical hierarchy in humans and macaques
Howell, A. M.; Warrington, S.; Fonteneau, C.; Cho, Y.; Sotiropoulos, S.; Murray, J. D.; Anticevic, A.
10.1101/2023.07.22.550168 — neuroscience — Posted on 2023-07-25
1016 The dynamics and geometry of choice in premotor cortex
Genkin, M.; Shenoy, K. V.; Chandrasekaran, C.; Engel, T. A.
10.1101/2023.07.22.550183 — neuroscience — Posted on 2023-07-25
1017 miRNA-encoded regulatory peptides modulate cadmium tolerance and accumulation in rice
Lu, L.; Chen, X.; Chen, J.; Zhang, Z.; Zhang, Z.; Sun, Y.; Wang, Y.; Xie, S.; Ma, Y.; Song, Y.; Zeng, R.
10.1101/2023.07.22.550150 — plant biology — Posted on 2023-07-25
1020 Collaborative network analysis for the interpretation of transcriptomics data in rare diseases, an application to Huntington's disease
Ozisik, O.; Kara, N. S.; Abbassi-Daloii, T.; Terezol, M.; Queralt-Rosinach, N.; Jacobsen, A.; Sezerman, O. U.; Roos, M.; Evelo, C. T.; Baudot, A.; Ehrhart, F.; Mina, E.
10.1101/2023.07.22.550153 — bioinformatics — Posted on 2023-07-25
1022 Whole genome approach to the structure and dynamics of Cacajao wild populations
Hermosilla-Albala, N.; Silva, F. E.; Cuadros-Espinoza, S.; Fontsere, C.; Valenzuela-Seba, A.; Gut, M.; Kelley, J. L.; Ruibal-Puertas, S.; Alentorn-Moron, P.; Faella, A.; Lizano, E.; Farias, I.; Hrbek, T.; Valsecchi, J.; Gut, I. G.; Rogers, J.; Farh, K. K.-H.; Kuderna, L. F. K.; Boubli, J. P.; Marques-Bonet, T.
10.1101/2023.07.22.550156 — evolutionary biology — Posted on 2023-07-25
1031 Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling
Hayes, A. M. R.; Tierno Lauer, L.; Kao, A. E.; Sun, S.; Klug, M. E.; Tsan, L.; Rea, J. J.; Subramanian, K. S.; Gu, C.; Tanios, N.; Ahuja, A.; Donohue, K. N.; Decarie-Spain, L.; Fodor, A. A.; Kanoski, S. E.
10.1101/2023.07.21.550120 — neuroscience — Posted on 2023-07-25
1032 Three-dimensional single-cell transcriptome imaging of thick tissues
Fang, R.; Halpern, A. R.; Rahman, M. M.; Huang, Z.; Lei, Z.; Hell, S. J.; Dulac, C.; Zhuang, X.
10.1101/2023.07.21.550124 — neuroscience — Posted on 2023-07-25
1033 Indirect and Direct Cannabinoid Agonists Differentially Affect Mesolimbic Dopamine Release and Related Behaviors
Honeywell, K. M.; Freels, T. G.; McWain, M. A.; Chaffin, A. S.; Nolen, H. G.; Sable, H. J.; Lester, D. B.
10.1101/2020.06.14.150755 — neuroscience — Posted on 2023-07-25
1034 Exuberant de novo dendritic spine growth in mature neurons
Kruessel, S.; Deb, I.; Son, S.; Ewall, G.; Chang, M.; Lee, H.-K.; Heo, W. D.; Kwon, H.-B.
10.1101/2023.07.21.550095 — neuroscience — Posted on 2023-07-25
1035 Molecular signatures of hyperexcitability and lithium responsiveness in bipolar disorder patient neurons provide alternative therapeutic strategies.
Khayachi, A.; Abuzgaya, M.; Liu, Y.; Jiao, C.; Dejgaard, K.; Schorova, L.; Kamesh, A.; He, Q.; Cousineau, Y.; Pietrantonio, A.; Farhangdoost, N.; Castonguay, C.-E.; Chaumette, B.; Alda, M.; Rouleau, G.; Milnerwood, A.
10.1101/2023.07.21.550088 — neuroscience — Posted on 2023-07-25
1036 Developmental trajectories of EEG aperiodic and periodic power suggest timing of thalamocortical development during infancy.
Wilkinson, C. L.; Yankowitz, L.; Chao, J. Y.; Gutierrez, R.; Rhoades, J. L.; Shinnar, S.; Purdon, P.; Nelson, C.
10.1101/2023.07.21.550114 — neuroscience — Posted on 2023-07-25
1037 FiPhA: An Open-Source Platform for Fiber Photometry Analysis
Bridge, M. F.; Wilson, L. R.; Panda, S.; Stevanovic, K. D.; Letsinger, A. C.; McBride, S. J.; Cushman, J. D.
10.1101/2023.07.21.550098 — neuroscience — Posted on 2023-07-25
1040 Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
Velez-Bermudez, I. C.; Lin, W.-D.; Chou, S.-J.; Chen, A.-P.; Schmidt, W.
10.1101/2023.07.22.550136 — plant biology — Posted on 2023-07-25
1045 Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer's disease
Cheng, G. W.-Y.; Ma, I. W.-T.; Huang, J.; Yeung, S. H.-S.; Ho, P.; Chen, Z.; Mak, H. K. F.; Herrup, K.; Chan, K. W. Y.; Tse, K.-H.
10.1101/2023.07.24.547147 — neuroscience — Posted on 2023-07-25
1046 Changes in spatial self-consciousness elicit grid cell-like representation in entorhinal cortex
Moon, H.-J.; Albert, L. P.; De Falco, E.; Tasu, C.; Gauthier, B.; Park, H.; Blanke, O.
10.1101/2023.07.21.550007 — neuroscience — Posted on 2023-07-25
1048 The penetration of sunflower root tissues by the parasitic plant Orobanche cumana Wallr. is intracellular
Auriac, M.-C.; Griffiths, C.; Robin-Soriano, A.; Legendre, A.; Boniface, M.-C.; Munos, S.; Fournier, J.; Chabaud, M.
10.1101/2023.07.24.550254 — plant biology — Posted on 2023-07-25
1049 Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin
Jiang, W. I.; Belly, H. D.; Wang, B. K.; Wong, A.; Kim, M.; Oh, F.; DeGeorge, J.; Huang, X.; Guang, S.; Weiner, O. K.; Ma, D. K.
10.1101/2023.07.25.550452 — physiology — Posted on 2023-07-25
1051 ScopeViewer: A Browser-Based Solution for Visualizing Spatial Transcriptomics Data
Luo, D.; Robertson, S.; Zhan, Y.; Rong, R.; Wang, S.; Jiang, X.; Yang, S.; Palmer, S.; Jia, L.; Li, Q.; Xiao, G.; Zhan, X.
10.1101/2023.07.24.549256 — bioinformatics — Posted on 2023-07-25
1052 Prominent contributions of selective neuronal subtypes to pediatric drug-resistant focal dysplasia
Zhang, Y.; Li, L.; Zhu, F.; Zhang, X.; Xia, D.; Zhong, C.; Liang, S.; Cao, D.; Zou, H.; Duan, J.; Shu, Y.; Yao, Y.; Song, J.; Hu, S.; Liao, J.; Zhou, Q.
10.1101/2023.07.21.549980 — bioinformatics — Posted on 2023-07-25
1055 Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions
Omo-Lamai, S.; Zamora, M. E.; Patel, M. N.; Wu, J.; Nong, J.; Wang, Z.; Peshkova, A.; Chase, L. S.; Essien, E.-O.; Muzykantov, V.; Marcos-Contreras, O. A.; Myerson, J. W.; Brenner, J. S.
10.1101/2023.07.21.550080 — bioengineering — Posted on 2023-07-25
1057 Extraordinary preservation of gene collinearity over three hundred million years revealed in homosporous lycophytes
Li, C.; Wickell, D.; Kuo, L.-Y.; Chen, X.; Nie, B.; Liao, X.; Peng, D.; Ji, J.; Jenkins, J. W.; Williams, M.; Shu, S.; Plott, C.; Barry, K. W.; Rajasekar, S.; Grimwood, J.; Han, X.; Sun, S.; Hou, Z.; He, W.; Dai, G.; Sun, C.; Schmutz, J.; Leebens-Mack, J.; Li, F.-W.; Wang, L.
10.1101/2023.07.24.548637 — genomics — Posted on 2023-07-25
1068 Dopamine challenge reduces mental state attribution accuracy
Schuster, B. A.; Sowden, S.; Rybicki, A. J.; Fraser, D. S.; Press, C.; Hickman, L.; Holland, P.; Cook, J. L.
10.1101/2023.07.21.550065 — neuroscience — Posted on 2023-07-25
1069 Evaluation of gliovascular functions of Aqp4 readthrough isoforms
Mueller, S. M.; White, K. M.; Fass, S. B.; Chen, S.; Shi, Z.; Ge, X.; Engelbach, J. A.; Gaines, S. H.; Bice, A. R.; Vasek, M. J.; Garbow, J. R.; Culver, J. P.; Martinez-Lozada, Z.; Cohen-Salmon, M.; Dougherty, J. D.; Sapkota, D.
10.1101/2023.07.21.549379 — neuroscience — Posted on 2023-07-25
1070 Human primary motor cortex indexes the onset of subjective intention in brain-machine-interface mediated actions
Noel, J.-P.; Bockbrader, M.; Colachis, S.; Solca, M.; Orepic, P.; Ganzer, P.; Haggard, P.; Rezai, A.; Blanke, O.; Serino, A.
10.1101/2023.07.21.550067 — neuroscience — Posted on 2023-07-25
1071 Length-dependent RNA foci formation and RAN translation are associated with SCA12 disorder
Kumar, M.; Sahni, S.; Anand, V.; Kumar, D.; Kushwah, N.; Goel, D.; Kapoor, H.; Srivastava, A. K.; Faruq, M. S.
10.1101/2023.07.21.550051 — neuroscience — Posted on 2023-07-25
1072 Sensory event-related potential morphology predicts age in premature infants
Zandvoort, C. S.; van der Vaart, M.; Robinson, S.; Usman, F.; Schmidt Mellado, G.; Evans Fry, R.; Worley, A.; Adams, E.; Slater, R.; Baxter, L.; de Vos, M.; Hartley, C.
10.1101/2023.07.21.549656 — neuroscience — Posted on 2023-07-25
1073 APOE4/4 is linked to damaging lipid droplets in Alzheimer's microglia
Haney, M.; Palovics, R.; Munson, C.; Long, C.; Johansson, P.; Yip, O.; Dong, W.; Rawat, E.; West, E.; Schlachetzki, J.; Tsai, A. P.-Y.; Guldner, I.; Lamichhane, B.; Smith, A.; Schaum, N.; Calcuttawala, K.; Shin, A.; Wang, Y.-H.; Wang, C.; Koutsodendris, N.; Serrano, G. E.; Beach, T.; Reiman, E. M.; Glass, C.; Abu-Remaileh, M. M.; Enejder, A.; Huang, Y.; Wyss-Coray, T.
10.1101/2023.07.21.549930 — neuroscience — Posted on 2023-07-25
1074 Mechanoreceptive Aβ primary afferents discriminate naturalistic social touch inputs at a functionally relevant time scale
Xu, S.; Hauser, S. C.; Nagi, S. S.; Jablonski, J. A.; Rezaei, M.; Jarocka, E.; Marshall, A. G.; Olausson, H.; McIntyre, S.; Gerling, G. J.
10.1101/2023.07.22.549516 — neuroscience — Posted on 2023-07-25
1076 Mobile version of the Battery for the Assessment of Auditory Sensorimotor and Timing Abilities (BAASTA): Implementation and adult norms
Dalla Bella, S.; Foster, N.; Laflamme, H.; Zagala, A.; Kadi, M.; Komeilipoor, N.; Blais, M.; Rigoulot, S.; Kotz, S. A.
10.1101/2023.07.21.550031 — neuroscience — Posted on 2023-07-25
1078 Linoleic acid supplementation reverses microglial response to diet induced-obesity at hypothalamic, cortical and subcortical level in mice
Jantzen, L.; Dumontoy, S.; Ramadan, B.; Houdayer, C.; Haffen, E.; Hichami, A.; Khan, N.; Van Waes, V.; Cabeza, L.
10.1101/2023.07.21.549983 — neuroscience — Posted on 2023-07-25
1080 Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer
Hockings, H.; Lakatos, E.; Huang, W.; Mossner, M.; Khan, M. A.; Metcalf, S.; Nicolini, F.; Smith, K.; Baker, A.-M.; Graham, T.; Lockley, M.
10.1101/2023.07.21.549688 — cancer biology — Posted on 2023-07-25
1081 Tumor-reactive clonotype dynamics underlying clinical response to TIL therapy in melanoma
Chiffelle, J.; Barras, D.; Petremand, R.; Orcurto, A.; Bobisse, S.; Arnaud, M.; Auger, A.; Navarro Rodrigo, B.; Ghisoni, E.; Sauvage, C.; Saugy, D.; Michel, A.; Murgues, B.; Fahr, N.; Imbimbo, M.; Ochoa-de-Olza, M.; Latifyan, S.; Crespo, I.; Benedetti, F.; Genolet, R.; Queiroz, L.; Schmidt, J.; Homicsko, K.; Zimmermann, S.; Michielin, O.; Bassani-Sternberg, M.; Kandalaft, L. E.; Dafni, U.; Corria Osorio, J.; Trueb, L.; Dangaj Laniti, D.; Harari, A.; Coukos, G.
10.1101/2023.07.21.544585 — cancer biology — Posted on 2023-07-25
1083 Label-free differentiation of functional zones in mature mouse placenta using micro-Raman imaging
Inanc, A.; Bektas, N. I.; Kecoglu, I.; Parlatan, U.; Durkut, B.; Ucak, M.; Unlu, M. B.; Celik-Ozenci, C.
10.1101/2023.07.21.550049 — biophysics — Posted on 2023-07-25
1087 A Strategy for Differential Abundance Analysis of Sparse Microbiome Data with Group-wise Structured Zeros
Abegaz, F.; Abedini, D.; White, F.; Guerrieri, A.; Zancarini, A.; Dong, L.; Westerhuis, J. A.; van Eeuwijk, F.; Bouwmeester, H.; Smilde, A. K.
10.1101/2023.07.24.549296 — bioinformatics — Posted on 2023-07-25
1090 Ultra-high density imaging arrays for diffuse optical tomography of human brain improve resolution, signal-to-noise, and information decoding
Markow, Z. E.; Trobaugh, J. W.; Richter, E. J.; Tripathy, K.; Rafferty, S. M.; Svoboda, A. M.; Schroeder, M. L.; Burns-Yocum, T. M.; Bergonzi, K. M.; Chevillet, M. A.; Mugler, E. M.; Eggebrecht, A. T.; Culver, J. P.
10.1101/2023.07.21.549920 — bioengineering — Posted on 2023-07-25
1091 Concurrent profiling of multiscale 3D genome organization and gene expression in single mammalian cells
Zhou, T.; Zhang, R.; Jia, D.; Doty, R. T.; Munday, A. D.; Gao, D.; Xin, L.; Abkowitz, J. L.; Duan, Z.; Ma, J.
10.1101/2023.07.20.549578 — genomics — Posted on 2023-07-25
1093 Extracellular release of a disintegrin and metalloproteinases orchestrates periodontal disease severity
Aljohmani, A.; Heinze, H.; Gharzia, F. G.; Reda, B.; Abdrabou, A. M. M. A.; Becker, S.; Bischoff, M.; Hannig, M.; Yildiz, D.
10.1101/2023.07.21.550016 — immunology — Posted on 2023-07-25
1094 Functional Connectivity Development along the Sensorimotor-Association Axis Enhances the Cortical Hierarchy
Luo, A.; Sydnor, V. J.; Pines, A.; Larsen, B.; Alexander-Bloch, A. F.; Cieslak, M.; Covitz, S.; Chen, A.; Esper, N. B.; Feczko, E.; Franco, A. R.; Gur, R. E.; Gur, R. C.; Houghton, A.; Hu, F.; Keller, A. S.; Kiar, G.; Mehta, K.; Salum, G. A.; Tapera, T.; Xu, T.; Zhao, C.; Fair, D. A.; Salo, T.; Shinohara, R. T.; Milham, M. P.; Satterthwaite, T. D.
10.1101/2023.07.20.549090 — neuroscience — Posted on 2023-07-25
1098 Synthetic Eco-Evolutionary Dynamics in Simple Molecular Environment
Casiraghi, L.; Mambretti, F.; Tovo, A.; Paraboschi, E. M.; Suweis, S.; Bellini, T.
10.1101/2023.07.21.549992 — ecology — Posted on 2023-07-25
1099 Functional variations in gamma-secretase activity are critical determinants of the clinical, biomarker, and cognitive progression of autosomal dominant Alzheimer's disease
Schultz, S.; Liu, L.; Schultz, A.; Fitzpatrick, C.; Levin, R.; Bellier, J.-P.; Shirzadi, Z.; Mathurin, N.; Chen, C.; Benzinger, T.; Day, G.; Farlow, M.; Gordon, B.; Hassenstab, J.; Jack, C.; Jucker, M.; Karch, C.; Lee, J.; Levin, J.; Perrin, R.; Schofield, P.; Xiong, C.; Johnson, K.; McDade, E.; Bateman, R.; Sperling, R.; Selkoe, D.; Chhatwal, J.; the Dominantly Inherited Alzheimer's Network Investigators,
10.1101/2023.07.04.547688 — neuroscience — Posted on 2023-07-25
1105 Small Molecule Protein Assembly Modulators with Pan-Cancer Therapeutic Efficacy
Lingappa, A. F.; Akintunde, O.; Ewald, C.; Froehlich, M.; Ziari, N.; Michon, M.; Yu, S. F.; Mallesh, S.; Lin, J.; Kitaygorodskyy, A.; Solas, D.; Reed, J. C.; Lingappa, J. R.; Mueller-Schiffmann, A.; Korth, C.; Prasad, M. D.; Aston, E.; Fabbri, B.; Nalca, A.; Anand, S.; Campi, T. W.; Petrouski, E.; Dey, D.; Andrews, D. W.; Lingappa, V. R.
10.1101/2022.09.28.509937 — cancer biology — Posted on 2023-07-25
1106 Biomolecular condensates modulate membrane lipid packing and hydration
Mangiarotti, A.; Siri, M.; Tam, N.; Zhao, Z.; Malacrida, L.; Dimova, R.
10.1101/2023.01.04.522768 — biophysics — Posted on 2023-07-25
1107 Activation of hTREK-1 by polyunsaturated fatty acids does not only involve membrane tension
Bechard, E.; Arel, E.; Bride, J.; Louradour, J.; Bussy, X.; Elloumi, A.; Vigor, C.; SOULE, P.; Oger, C.; Galano, J.-M.; Durand, T.; Le Guennec, J.-Y.; moha-ou-maati, H.; Demion, M.
10.1101/2022.08.01.502268 — biophysics — Posted on 2023-07-25
1110 Five inhibitory receptors display distinct vesicular distributions in T cells
Lu, J.; Veler, A.; Simonetti, B.; Raj, T.; Chou, P. H.; Cross, S. J.; Phillips, A. M.; Ruan, X.; Huynh, L.; Dowsey, A. W.; Ye, D.; Murphy, R. F.; Verkade, P.; Cullen, P. J.; Wuelfing, C.
10.1101/2023.07.21.550019 — immunology — Posted on 2023-07-25
1113 Surprising variety in the USP deubiquitinase catalytic mechanism
Keijzer, N.; Priyanka, A.; Stijf-Bultsma, Y.; Fish, A.; Gersch, M.; Sixma, T. K.
10.1101/2023.07.24.550302 — biochemistry — Posted on 2023-07-24
1116 Growth directions and stiffness across cell layers determine whether tissues stay smooth or buckle
Yadav, A. S.; Hong, L.; Klees, P. M.; Kiss, A.; He, X.; Barrios, I. M.; Heeney, M.; Galang, A. M. D.; Smith, R. S.; Boudaoud, A.; Roeder, A. H. K.
10.1101/2023.07.22.549953 — developmental biology — Posted on 2023-07-24
1120 Gut microbiota and faecal cytokine profiles of rural Cambodian infants and links to early life nutrition and diarrhoeal episodes.
Dalby, M. J.; Kiu, R.; Serghiou, I. R.; Miyazaki, A.; Acford-Palmer, H.; Tung, R.; Caim, S.; Phillips, S.; Kujawska, M.; Matsui, M.; Iwamoto, A.; Taking, B.; Cox, S. E.; Hall, L. J.
10.1101/2023.07.24.550269 — microbiology — Posted on 2023-07-24
1121 A humoral stress response protects Drosophila tissues from antimicrobial peptides
Rommelaere, S.; Carboni, A.; Bada Juarez, J. F.; Boquete, J.-P.; Abriata, L. A.; Teixeira Pinto Meireles, F.; Rukes, V.; Vincent, C. M.; Kondo, S.; Dionne, M. S.; Dal Peraro, M.; Cao, C.; Lemaitre, B.
10.1101/2023.07.24.550293 — immunology — Posted on 2023-07-24
1123 Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology
Gazula, H.; Tregidgo, H.; Billot, B.; Balbastre, Y.; Williams-Ramirez, J.; Herisse, R.; Deden-Binder, L. J.; Casamitjana, A.; Melief, E. J.; Latimer, C. S.; Kilgore, M. D.; Montine, M.; Robinson, E.; Blackburn, E.; Marshall, M. S.; Connors, T. R.; Oakley, D. H.; Frosh, M. P.; Young, S. I.; Van Leemput, K.; Dalca, A. V.; Fischl, B.; Mac Donald, C. L.; Keene, C. D.; Hyman, B.; Iglesias, J. E.
10.1101/2023.06.08.544050 — neuroscience — Posted on 2023-07-24
1124 Harnessing deep learning to analyze cryptic morphological variability of Marchantia polymorpha
Tomizawa, Y.; Minamino, N.; Shimokawa, E.; Kawamura, S.; Komatsu, A.; Hiwatashi, T.; Nishihama, R.; Ueda, T.; Kohchi, T.; Kondo, Y.
10.1101/2023.05.31.543177 — plant biology — Posted on 2023-07-24
1125 Natural disaster alters the adaptive benefits of sociality
Testard, C.; Shergold, C.; Acevedo-Ithier, A.; Hart, J.; Negron-Del Valle, J.; Philips, D.; Watowich, M.; Sanguinetti-Scheck, J. I.; Montague, M.; Snyder-Mackler, N. J.; Higham, J.; Platt, M.; Brent, L. J.
10.1101/2023.07.17.549328 — animal behavior and cognition — Posted on 2023-07-24
1128 Neurogenomic landscape associated with status-dependent cooperative behavior
Bolton, P. E.; Ryder, T. B.; Dakin, R.; Houtz, J. L.; Moore, I. T.; Balakrishnan, C. N.; Horton, B. M.
10.1101/2022.10.05.510848 — evolutionary biology — Posted on 2023-07-24
1130 In vivo reprogramming and epigenetic rejuvenation of adult cardiomyocytes ameliorate heart failure in mice
de Lazaro, I.; Zhang, B.; Makarova, N. E.; Mariotti, M.; Orejon-Sanchez, T. L.; Tringides, C. M.; Gladyshev, V. N.; Mooney, D.
10.1101/2021.12.22.473302 — developmental biology — Posted on 2023-07-24
1135 A host shift as the origin of tomato bacterial canker caused by Clavibacter michiganensis
Yanez-Olvera, A. G.; Gomez-Diaz, A. G.; Selem-Mojica, N.; Rodriguez-Orduna, L.; Lara-Avila, J. P.; Varni, V.; Alcoba, F.; Croce, V.; Siri, M. I.; Clavibacter consortium, ; Barona-Gomez, F.
10.1101/2023.07.24.550321 — microbiology — Posted on 2023-07-24
1137 tUbe net: a generalisable deep learning tool for 3D vessel segmentation
Holroyd, N. A.; Li, Z.; Walsh, C.; Brown, E. E.; Shipley, R. J.; Walker-Samuel, S.
10.1101/2023.07.24.550334 — microbiology — Posted on 2023-07-24
1141 Metabolic Symbiosis between Oxygenated and Hypoxic Tumour Cells: An Agent-based Modelling Study
Jayathilake, P.; Victori, P.; Pavillet, C.; Voukantsis, D.; Miar Cuervo, A.; Arora, A.; Harris, A. L.; Morten, K.; Buffa, F. M.
10.1101/2023.07.24.550289 — systems biology — Posted on 2023-07-24
1143 Surprising variety in the USP deubiquitinase catalytic mechanism
Keijzer, N.; Priyanka, A.; Stijf-Bultsma, Y.; Fish, A.; Gersch, M.; Sixma, T. K.
10.1101/2023.07.24.550302 — biochemistry — Posted on 2023-07-24
1145 Increased thermal tolerance under anoxic conditions in an extremophile fish from hot sulfur springs in Mexico
Pacher, K.; Hernandez-Roman, N.; Juarez-Lopez, A.; Jimenez-Jimenez, J. E.; Lukas, J.; Sevinchan, Y.; Krause, J.; Arias-Rodriguez, L.; Bierbach, D.
10.1101/2023.07.21.550037 — ecology — Posted on 2023-07-24
1154 Genetic characterization and dissemination of Staphylococcus aureus and Staphylococci genus: food and health perspective
M Alkuraythi, D.; M. Alkhulaifi, M.; Z. Binjomah, A.; Alarawi, M.; M Aldakhil, H.; I. Mujallad, M.; Ali Alharbi, S.; Alshomrani, M.; Mastour Alshahrani, S.; Gojobori, T.; Alajel, S. M.
10.1101/2023.07.24.550257 — microbiology — Posted on 2023-07-24
1155 Characterization of the RofA regulon in the pandemic M1global and emergent M1UK lineages of Streptococcus pyogenes
Zhi, X.; Vieira, A.; Huse, K. K.; Martel, P. J.; Lobkowicz, L.; Li, H. K.; Croucher, N.; Andrew, I.; Game, L.; Sriskandan, S.
10.1101/2023.07.23.550082 — microbiology — Posted on 2023-07-24
1156 Mechanisms of extracellular electron transfer in anaerobic methanotrophic archaea
Ouboter, H. T.; Mesman, R.; Sleutels, T.; Postma, J.; Wissink, M.; Jetten, M. S. M.; ter Heijne, A.; Berben, T.; Welte, C.
10.1101/2023.07.24.550278 — microbiology — Posted on 2023-07-24
1164 MERTK Coordinates Efferocytosis by Regulating Integrin Localization and Activation
Dickson, B. H.; Tasnim, T.; Lam, A. L.; Vreize, A.; Blythe, E. N.; Dekaban, G. A.; Heit, B.
10.1101/2023.07.20.549870 — immunology — Posted on 2023-07-24
1166 HaploCatcher: An R Package for Prediction of Haplotypes
Winn, Z. J.; Hudson-Arns, E.; Hammers, M.; DeWitt, N. D.; Lyerly, J.; Bai, G.; St Amand, P.; Nachappa, P.; Haley, S. D.; Mason, E.
10.1101/2023.07.20.549744 — plant biology — Posted on 2023-07-24
1168 Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore
Rao, S.; Strong, L. M.; Ren, X.; Skulsuppaisarn, M.; Lazarou, M.; Hurley, J. H.; Hummer, G.
10.1101/2023.07.17.549391 — cell biology — Posted on 2023-07-24
1169 Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice
Obr, M.; Percipalle, M.; Chernikova, D.; Yang, H.; Thader, A.; Pinke, G.; Porley, D.; Mansky, L. M.; Dick, R.; Schur, F. K.
10.1101/2023.07.24.548988 — molecular biology — Posted on 2023-07-24
1170 RNAi-based screen for cuticle pigmentation in Drosophila melanogaster reveals novel regulators of brain dopamine
Deal, S. L.; Bei, D.; Gibson, S. B.; Delgado-Seo, H.; Fujita, Y.; Wilwayco, K.; Seto, E. S.; Yamamoto, S.
10.1101/2023.07.20.549932 — neuroscience — Posted on 2023-07-24
1171 A Molecular Basis of Human Brain Connectivity
Ng, B.; Tasaki, S.; Greathouse, K.; Walker, C.; Zhang, A.; Covitz, S.; Cieslak, M.; Adamson, A.; Andrade, J.; Poovey, E.; Curtis, K.; Muhammad, H.; Seidlitz, J.; Satterthwaite, T.; Bennett, D.; Seyfried, N.; Vogel, J.; Gaiteri, C.; Herskowitz, J.
10.1101/2023.07.20.549895 — neuroscience — Posted on 2023-07-24
1173 Cortical and subcortical mapping of the allostatic-interoceptive system in the human brain: replication and extension with 7 Tesla fMRI
Zhang, J.; Chen, D.; Srirangarajan, T.; Theriault, J.; Kragel, P. A.; Hartley, L.; Lee, K. M.; McVeigh, K.; Wager, T.; Wald, L. L.; Satpute, A. B.; Quigley, K. S.; Whitfield-Gabrieli, S.; Barrett, L. F.; Bianciardi, M.
10.1101/2023.07.20.548178 — neuroscience — Posted on 2023-07-24
1176 The short-term acquisition of a skill learning task unveils the neural filtering of shared synaptic input to spinal motor neurons
Cabral, H. V.; Cudicio, A.; Bonardi, A.; Del Vecchio, A.; Falciati, L.; Orizio, C.; Martinez-Valdes, E.; Negro, F.
10.1101/2023.07.20.549840 — neuroscience — Posted on 2023-07-24
1179 Addressing persistent challenges in digital image analysis of cancerous tissues
Prabhakaran, S.; Yapp, C.; Baker, G. J.; Beyer, J.; Chang, Y. H.; Creason, A. L.; Krueger, R.; Muhlich, J.; Patterson, N. H.; Sidak, K.; Sudar, D.; Taylor, A. J.; Ternes, L.; Troidl, J.; Yubin, X.; Sokolov, A.; Tyson, D. R.; Participants of the Cell Imaging Hackathon 2022,
10.1101/2023.07.21.548450 — bioinformatics — Posted on 2023-07-24
1186 Endothelial SARS-CoV-2 infection is not the underlying cause of COVID19-associated vascular pathology in mice
Gao, S.; Tang, A. T.; Wang, M.; Buchholz, D. W.; Imbiakha, B.; Yang, J.; Chen, X.; Hewins, P.; Mericko-Ishizuka, P.; Leu, N. A.; Sterling, S.; August, A.; Jurado, K.; Morrisey, E.; Aguilar-Carreno, H.; Kahn, M. L.
10.1101/2023.07.24.550352 — pathology — Posted on 2023-07-24
1189 A Novel Genome Optimization Tool for Chromosome-Level Assembly across Diverse Sequencing Techniques
Chuang, W. H.; Cheng, H.-C.; Chang, Y.-J.; Huang, Y.-C.; Fu, P.-Y.; Hsieh, P.-H.; Chen, S.-H.; Kwok, P.-Y.; Lin, C.-Y.; Ho, J.-M.
10.1101/2023.07.20.549842 — genomics — Posted on 2023-07-24
1193 Metabolomic rearrangement controls the intrinsic microbial response to temperature changes
Knapp, B.; Willis, L.; Gonzalez, C.; Vashistha, H.; Touma, J. J.; Tikhonov, M.; Ram, J.; Salman, H.; Elias, J. E.; Huang, K. C.
10.1101/2023.07.22.550177 — cell biology — Posted on 2023-07-24
1194 MiniBAR/KIAA0355 is a dual Rac and Rab effector required for ciliogenesis
Shaughnessy, R.; Serres, M.; Escot, S.; Hammich, H.; Cuvelier, F.; Salles, A.; Rocancourt, M.; Verdon, Q.; Gaffuri, A.-L.; Sourigues, Y.; Malherbe, G.; Velikovsky, L.; Chardon, F.; Tinevez, J.-Y.; Callebaut, I.; Formstecher, E.; Houdusse, A.; David, N.; Pylypenko, O.; Echard, A.
10.1101/2023.07.24.550339 — cell biology — Posted on 2023-07-24
1195 A genome-wide single-cell 3D genome atlas of lung cancer progression
Liu, M.; Jin, S.; Agabiti, S. S.; Jensen, T. B.; Yang, T.; Radda, J. S. D.; Ruiz, C. F.; Baldissera, G.; Muzumdar, M. D.; Wang, S.
10.1101/2023.07.23.550157 — cell biology — Posted on 2023-07-24
1197 Mecp2 Fine-tunes Quiescence Exit by Targeting Nuclear Receptors
Yang, J.; Zou, S.; Qiu, Z.; Lai, M.; Long, Q.; Chen, H.; Zhang, S.; Xie, X.; Gong, Y.; Liu, A.; Li, M.; Bai, X.
10.1101/2023.07.24.550263 — cell biology — Posted on 2023-07-24
1200 Downregulation of a cell polarity protein potentiates Chikungunya Virus infection in host cells
Kumar, R.; Tatiya, P.; Dey, D.; Ratra, Y.; Mian, S. Y.; Chaudhary, S.; Suhag, K.; Basak, S.; Banerjee, M.
10.1101/2023.07.24.550336 — cell biology — Posted on 2023-07-24
1201 Evolution of cullin E3 ubiquitin ligases and function in trypanosomes
del Pino, R. C.; Zoltner, M.; Yamada, K.; Butterfield, E. R.; Field, M.
10.1101/2023.07.24.550360 — cell biology — Posted on 2023-07-24
1203 Genomic epidemiology of European Aspergillus fumigatus causing COVID-19-associated pulmonary aspergillosis in Europe
Simmons, B.; Rhodes, J.; Rogers, T.; Talento, A. F.; Griffin, A.; Mansfield, M.; Abdolrasouli, A.; Verweij, P. E.; Bosch, T.; Schelenz, S.; Hemmings, S.; Sheehan, D.; Fisher, M. C.
10.1101/2023.07.21.550109 — microbiology — Posted on 2023-07-24
1204 Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress
Mikati, M. O.; Erdmann-Gilmore, P.; Connors, R.; Conway, S. M.; Malone, J.; Woods, J.; Sprung, R. W.; Townsend, R. R.; Al-Hasani, R.
10.1101/2023.02.15.528745 — neuroscience — Posted on 2023-07-24
1205 Low dimensional criticality embedded in high dimensional awake brain dynamics
Fontenele, A. J.; Sooter, J. S.; Norman, V. K.; Gautam, S. H.; Shew, W.
10.1101/2023.01.05.522896 — neuroscience — Posted on 2023-07-24
1208 Cost-effectiveness of Precision Guided SIT for Control of Anopheles gambiae in the Upper River Region, The Gambia.
Gendron, W. A. C.; Raban, R.; Mondal, A.; Sanchez C., H. M.; Smidler, A.; Zilberman, D.; Ilboudo, P. G.; D'Alessandro, U.; Marshall, J. M.; Akbari, O. S.
10.1101/2023.07.20.549762 — genetics — Posted on 2023-07-24
1210 Blood and cerebellar abundance of ATXN3 splice variants in spinocerebellar ataxia type 3/Machado-Joseph disease
Raposo, M.; Hubener-Schmid, J.; Tagett, R.; Ferreira, A. F.; Vieira Melo, A. R.; Vasconcelos, J.; Pires, P.; Kay, T.; Garcia-Moreno, H.; Giunti, P.; Santana, M. M.; Pereira de Almeida, L.; Infante, J.; van de Warrenburg, B. P.; de Vries, J. J.; Faber, J.; Klockgether, T.; Casadei, N.; Admard, J.; Schols, L.; Riess, O.; European Spinocerebellar ataxia type 3/Machado-Joseph disease Initiative (ESMI) study group, ; Costa, M. d. C.; Lima, M.
10.1101/2023.04.22.537936 — genetics — Posted on 2023-07-24
1212 The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle
Azam, S.; Armijo, K. S.; Weindel, C. G.; Devigne, A.; Nakagawa, S.; Hirose, T.; Carpenter, S. L.; Watson, R. O.; Patrick, K. L.
10.1101/2023.05.11.540384 — immunology — Posted on 2023-07-24
1213 A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis
Paasch, B. C.; Sohrabi, R.; Kremer, J. M.; Nomura, K.; Martz, J.; Kvitko, B.; Tiedje, J. M.; He, S. Y.
10.1101/2023.03.02.527037 — plant biology — Posted on 2023-07-24
1215 Modeling fragment counts improves single-cell ATAC-seq analysis
Martens, L. D.; Yepez, V. A.; Fischer, D. S.; Theis, F. J.; Gagneur, J.
10.1101/2022.05.04.490536 — bioinformatics — Posted on 2023-07-24
1216 Characterization of the RBM15 protein binding with XCI-escaping long noncoding RNAs
Mayes, C.; Bose, E.; Ellis, L.; Baker, C.; Tambalotti, S.; Xiong, S.; Sarpong, Y. P. O.; Shalaby, M.; Barry, L.; Lewis, F.; Joseph, J.; Isaacs, T.; McCarthy, D.; Katz, D.; Wang, J.; Zirimu, V.; Vargas, L.; Von Hofe, J.; Aguilar, G.; Buchan, K.; Zheng, L.; Wolfe, G.; Jones, A.
10.1101/2023.07.20.549950 — biochemistry — Posted on 2023-07-24
1218 Dopamine-dependent cerebellar dysfunction enhances beta oscillations and disrupts motor learning in a multiarea model
Gambosi, B.; Sheiban, F. J.; Biasizzo, M.; Antonietti, A.; D'Angelo, E. U.; Mazzoni, A.; Pedrocchi, A.
10.1101/2023.07.18.549459 — neuroscience — Posted on 2023-07-24
1221 Graded multidimensional clinico-radiological variations in Alzheimer's disease and posterior cortical atrophy
Ingram, R. U.; Ocal, D.; Halai, A. D.; Pobric, G.; Cash, D.; Crutch, S. J.; Yong, K. X. X.; Lambon Ralph, M. A.
10.1101/2023.02.07.527424 — neuroscience — Posted on 2023-07-24
1223 Cocaine addiction-like behaviors are associated with long-term changes in gene regulation, energy metabolism, and GABAergic inhibition within the amygdala
Zhou, J. L.; de Guglielmo, G.; Ho, A. J.; Kallupi, M.; Pokhrel, N.; Li, H.-R.; Chitre, A. S.; Munro, D.; Mohammadi, P.; Carrette, L. L. G.; George, O.; Palmer, A. A.; McVicker, G. P.; Telese, F.
10.1101/2022.09.08.506493 — genomics — Posted on 2023-07-24
1224 Neuronal DAMPs exacerbate neurodegeneration via astrocytic RIPK3 signaling
Chang, N. P.; DaPrano, E. M.; Evans, W. R.; Nissenbaum, M.; McCourt, M.; Alzate, D.; Lindman, M.; Chou, T.-W.; Atkins, C.; Kusnecov, A. W.; Huda, R.; Daniels, B. P.
10.1101/2023.07.21.550097 — neuroscience — Posted on 2023-07-24
1225 A comprehensive atlas of the aging vertebrate brain reveals signatures of progressive proteostasis dysfunction
Di Fraia, D.; Marino, A.; Lee, J. H.; Kelmer Sacramento, E.; Baumgart, M.; Bagnoli, S.; Tomaz da Silva, P.; Kumar Sahu, A.; Siano, G.; Tiessen, M.; Gagneur, J.; Frydman, J.; Cellerino, A.; Ori, A.
10.1101/2023.07.20.549210 — systems biology — Posted on 2023-07-24
1226 Invasion of the stigma by the pollen tube or an oomycete pathogen: striking similarities and differences
Riglet, L.; Hok, S.; Kebdani-Minet, N.; Le Berre, J.; Gourgues, M.; Rozier, F.; Bayle, V.; Bancel-Vallee, L.; Allasia, V.; Keller, H.; da Rocha, M.; Gaude, T.; Attard, A.; FOBIS LOISY, I.
10.1101/2023.07.19.549726 — plant biology — Posted on 2023-07-24
1227 Phospholamban Inhibits the Cardiac Calcium Pump Through Reversing the Allosteric Enhancement of Calcium Affinity by ATP
Cleary, S. R.; Seflova, J.; Cho, E. E.; Bisht, K.; Khandelia, H.; Espinoza-Fonseca, L. M.; Robia, S. L.
10.1101/2023.07.20.549928 — biochemistry — Posted on 2023-07-24
1229 Trade-offs in a reef-building coral after six years of thermal acclimation
Roik, A.; Wall, M.; Dobelmann, M.; Nietzer, S.; Brefeld, D.; Fiesinger, A.; Reverter, M.; Schupp, P. J.; Jackson, M.; Rutsch, M.; Strahl, J.
10.1101/2023.07.20.549699 — ecology — Posted on 2023-07-24
1230 Essential role of the CCL2-CCR2 axis in Mayaro virus-induced disease
Santos, F. M.; Melo, V. C.; Araujo, S.; Sousa, C. D. F.; Moreira, T. P.; Goncalves, M. R.; Santos, A. C.; Seabra, H. A.; Costa, P. A. C.; Barrioni, B. R.; Souza, P. B.; Pereira, M. d. M.; Nogueira, M. L.; Souza, D. G.; Guimaraes, P. P.; Texeira, M. M.; Queiroz-Junior, C. M.; Costa, V. V.
10.1101/2023.07.21.550077 — cell biology — Posted on 2023-07-24
1231 Kita crispants for systematic image-based genetic screens of complex traits in zebrafish larvae
Mazzaferro, E.; Metzendorf, C.; Zhang, H.; Mujica, E.; Hoijer, I.; Alavioon, G.; Campos-Costa, J.; Cook, N. L.; Gry Vienberg, S.; Djordjevic, D.; Larsson, A. O.; Ameur, A.; Emmanouilidou, A.; Allalou, A.; den Hoed, M.
10.1101/2023.07.22.550161 — molecular biology — Posted on 2023-07-24
1232 Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
Thomas, C.; Van Dongen, K.; Leleu, D.; Pilot, T.; Jalil, A.; Mangin, L.; Menegaut, L.; Geissler, A.; IVANOV, S.; Laubriet, A.; Crespy, V.; Nguyen, M.; steinmetz, e.; Masson, D.; Gautier, T.
10.1101/2023.07.19.549799 — immunology — Posted on 2023-07-24
1237 Modelling Human Post-Implantation Development via Extra-Embryonic Niche Engineering
Hislop, J. J.; Alavi, A.; Song, Q.; Schoenberger, R. L.; Keshavarz F., K.; LeGraw, R.; Velazquez, J. J.; Mokhtari, T.; Taheri, M. N.; Rytel, M.; de Sousa Lopes, S. M. C.; Watkins, S. C.; Stolz, D. B.; Kiani, S.; Sozen, B.; Bar-Joseph, Z.; Ebrahimkhani, M.
10.1101/2023.06.15.545118 — developmental biology — Posted on 2023-07-24
1238 Mitochondrial dysfunction underlies impaired neurovascular coupling following traumatic brain injury
Van Hameren, G.; Muradov, J.; Minarik, A.; Aboghazleh, R.; Orr, S.; Cort, S.; Andrews, K.; McKenna, C.; Pham, N. t.; MacLean, M. A.; Friedman, A.
10.1101/2023.07.20.549872 — neuroscience — Posted on 2023-07-24
1240 Regulation of Motor-DNA Interactions in the Hetero-oligomeric Phage Lambda Terminase Holoenzyme
Rawson, B.; Ordyan, M.; Yang, Q.; Sippy, J.; Feiss, M.; Catalano, C. E.; Smith, D. E.
10.1101/2022.09.24.509349 — biophysics — Posted on 2023-07-24
1241 The International Weed Genomics Consortium: Community Resources for Weed Genomics Research
Montgomery, J. S.; Morran, S.; MacGregor, D. R.; McElroy, J. S.; Neve, P.; Neto, C.; Vila-Aiub, M. M.; Sandoval, M. V.; Menendez, A. I.; Kreiner, J.; Fan, L.; Caicedo, A. L.; Maughan, P. J.; Martins, B. A. B.; Mika, J.; Collavo, A.; Merotto, A.; Subramanian, N. K.; Bagavathiannan, M. V.; Cutti, L.; Islam, M. M.; Gill, B. S.; Cicchillo, R.; Gast, R.; Soni, N.; Wright, T. R.; Zastrow-Hayes, G.; May, G.; Malone, J. M.; Sehgal, D.; Kaundun, S. S.; Dale, R. P.; Vorster, B. J.; Peters, B.; Lerchl, J.; Tranel, P. J.; Beffa, R.; Jugulam, M.; Fengler, K.; Llaca, V.; Patterson, E. L.; Gaines, T. A.
10.1101/2023.07.19.549613 — genomics — Posted on 2023-07-24
1244 The influence of gene flow on population viability in an isolated urban caracal population
Kyriazis, C. C.; Serieys, L. E.; Bishop, J. M.; Drouilly, M.; Viljoen, S.; Wayne, R. K.; Lohmueller, K. E.
10.1101/2023.07.20.549918 — evolutionary biology — Posted on 2023-07-23
1246 Antibiotics of the future are prone to resistance in Gram-negative pathogens
Daruka, L.; Czikkely, M. S.; Szili, P.; Farkas, Z.; Balogh, D.; Maharramov, E.; Vu, T.-H.; Sipos, L.; Vincze, B. D.; Grezal, G.; Juhasz, S.; Dunai, A.; Daraba, A.; Szamel, M.; Sari, T.; Stirling, T.; Vasarhelyi, B. M.; Ari, E.; Christodoulou, C.; Manczinger, M.; Enyedi, M. Z.; Jaksa, G.; van Houte, S.; Pursey, E.; Papp, C. G.; Szilovics, Z.; Pinter, L.; Haracska, L.; Gacser, A.; Kintses, B.; Papp, B.; Pal, C.
10.1101/2023.07.23.550022 — microbiology — Posted on 2023-07-23
1247 The T cell receptor sequence influences the likelihood of T cell memory formation
Lagattuta, K. A.; Nathan, A.; Rumker, L.; Birnbaum, M. E.; Raychaudhuri, S.
10.1101/2023.07.20.549939 — immunology — Posted on 2023-07-23
1248 Distinct disease-modifying therapies are associated with different blood immune cell profiles in people with relapsing-remitting multiple sclerosis
Canto-Gomes, J.; Boleixa, D.; Teixeira, C.; Martins da Silva, A.; Gonzalez-Suarez, I.; Cerqueira, J. J.; Correia-Neves, M.; Nobrega, C.
10.1101/2023.07.20.549852 — immunology — Posted on 2023-07-23
1249 Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis
Harvey, J.; Smith, A. R.; Weymouth, L. S.; Smith, R. G.; Castanho, I.; Hubbard, L.; Creese, B.; Bresner, C.; Williams, N.; Pishva, E.; Lunnon, K.
10.1101/2023.07.20.549825 — neuroscience — Posted on 2023-07-23
1250 Anti-apoptotic and anti-inflammatory properties of grapefruit IntegroPectin on human microglial HMC3 cell line
Scordino, M.; Urone, G.; Frinchi, M.; Valenza, C.; Bonura, A.; Cipollina, C.; Ciriminna, R.; Meneguzzo, F.; Pagliaro, M.; Mudo, G.; Di Liberto, V.
10.1101/2023.07.20.549931 — neuroscience — Posted on 2023-07-23
1257 Slow conduction and spatial dispersion of repolarization are intrinsic properties of cardiomyocyte electrophysiology that contribute to proarrhythmia in an iPSC model of hypertrophic cardiomyopathy
Lim, S.; Mangala, M. M.; Holliday, M.; Szappanos, H. C.; Barratt-Ross, S.; Liang, W.; Ranpura, G.; Vandenberg, J. I.; Semsarian, C.; Hill, A. P.; Hool, L. C.
10.1101/2023.07.20.549952 — physiology — Posted on 2023-07-23
1258 Contribution of the delta-class glutathione S-transferase to agrochemical adaptation in Apis mellifera
Moural, T. W.; Koirala B K, S.; Bhattarai, G.; He, Z.; Guo, H.; Phan, N. T.; Rajotte, E. G.; Biddinger, D. J.; Hoover, K.; Zhu, F.
10.1101/2023.07.20.549922 — pharmacology and toxicology — Posted on 2023-07-23
1259 Synergistic efficacy of tigecycline combined with apramycin against tet(X)-harboring Acinetobacter spp.
Liu, J.; Zheng, S.-L.; Wu, J. J.; Zheng, M.; Cai, D.-T.; Zhang, Y.; Sun, J.; Liu, Y.-H.; Liao, X.-P.; Yu, Y.
10.1101/2023.07.20.549942 — pharmacology and toxicology — Posted on 2023-07-23
1261 Glial-derived mitochondrial signals impact neuronal proteostasis and aging.
Bar-Ziv, R.; Dutta, N.; Hruby, A.; Sukarto, E.; Henderson, H. R.; Durieux, J.; Tronnes, S. U.; Averbukh, M.; Alcala, A.; Ahmad, Q.; Bolas, T.; Perez, J.; Dishart, J. G.; Vega, M.; Garcia, G.; Higuchi-Sanabria, R.; Dillin, A.
10.1101/2023.07.20.549924 — genetics — Posted on 2023-07-23
1264 Machine learning illuminates how diet influences the evolution of yeast galactose metabolism
Harrison, M.-C.; Ubbelohde, E. J.; LaBella, A. L.; Opulente, D. A.; Wolters, J. F.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Hittinger, C. T.; Rokas, A.
10.1101/2023.07.20.549758 — evolutionary biology — Posted on 2023-07-23
1267 Trade-offs in a reef-building coral after six years of thermal acclimation
Roik, A.; Wall, M.; Dobelmann, M.; Nietzer, S.; Brefeld, D.; Fiesinger, A.; Reverter, M.; Schupp, P. J.; Jackson, M.; Rutsch, M.; Strahl, J.
10.1101/2023.07.20.549699 — ecology — Posted on 2023-07-23
1268 Long-lived coherences for magnetic interactions in proteins
Teleanu, F.; Ciumeica, A.; Ianc, O.; Lupulescu, A.; Sadet, A.; Vasos, P. R.
10.1101/2023.07.22.550138 — molecular biology — Posted on 2023-07-23
1271 Phage-mediated dispersal of multicellular bacteria
Jaffal, H.; Korbeti, M.; Misson, P.; Tavares, P.; Ouldali, M.; Leh, H.; Lautru, S.; Lioy, V. S.; Lecointe, F.; Bury-Mone, S. G.
10.1101/2023.07.22.549817 — microbiology — Posted on 2023-07-23
1273 Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells
Cloarec-Ung, F.-M.; Beaulieu, J.; Suthananthan, A.; Lehnertz, B.; Sauvageau, G.; Sheppard, H. M.; Knapp, D. J.
10.1101/2023.05.26.542436 — bioengineering — Posted on 2023-07-23
1274 Automated system for training and assessing string-pulling behaviors in rodents
Jordan, G. A.; Vishwanath, A.; Holguin, G.; Bartlett, M. J.; Tapia, A. K.; Winter, G. M.; Sexauer, M. M.; Stopera, C. J.; Falk, T.; Cowen, S. L.
10.1101/2023.07.02.547431 — bioengineering — Posted on 2023-07-23
1275 The balance between shear flow and extracellular matrix in ovarian cancer-on-chip
Chen, C.; Boche, A.; Lopez, E.; Peng, J.; Carreiras, F.; Schanne-Klein, M.-C.; Chen, Y.; Lambert, A.; Aime, C.
10.1101/2023.07.20.549914 — bioengineering — Posted on 2023-07-23
1276 Maternal adaptations in mouse lactation are vulnerable to diet-induced excess adiposity
Breznik, J. A.; Ribeiro, T. A.; Yeo, E.; Kennelly, B. K.; Wang, X.; Quin, C.; Cowbrough, B.; Verdu, E. F.; Bowdish, D. M. E.; Sloboda, D. M.
10.1101/2023.06.30.547298 — developmental biology — Posted on 2023-07-23
1277 Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Martin, S. D.; Connor, T.; Sanigorski, A.; McEwen, K. A.; Henstridge, D. C.; Nijagal, B.; De Souza, D. P.; Tull, D.; Meikle, P.; Kowalski, G. M.; Bruce, C.; Gregorevic, P.; Febbraio, M.; Collier, F.; Walder, K. R.; McGee, S.
10.1101/2022.10.17.512492 — cell biology — Posted on 2023-07-23
1278 KSHV vIL-6 Enhances Inflammatory Responses by Epigenetic Reprogramming
Inagaki, T.; Wang, K.-H.; Kumar, A.; Izumiya, C.; Miura, H.; Komaki, S.; Davis, R. R.; Tepper, C.; Katano, H.; Shimoda, M.; Izumiya, Y.
10.1101/2023.06.25.546454 — microbiology — Posted on 2023-07-23
1281 Neuroticism/negative emotionality is associated with increased reactivity to uncertain threat in the bed nucleus of the stria terminalis, not the amygdala
Grogans, S. E.; Hur, J.; Barstead, M. G.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Fox, A. S.; Smith, J. F.; DeYoung, K. A.; Shackman, A. J.
10.1101/2023.02.09.527767 — neuroscience — Posted on 2023-07-23
1282 Host-gut microbiota interactions shape parasite infections in farmed Atlantic salmon
Brealey, J. C.; Kodama, M.; Rasmussen, J. A.; Hansen, S. B.; Santos-Bay, L.; Lecaudey, L. A.; Hansen, M.; Fjaere, E.; Myrmel, L. S.; Madsen, L.; Bernhard, A.; Sveier, H.; Kristiansen, K.; Gilbert, M. T. P.; Martin, M. D.; Limborg, M. T.
10.1101/2023.07.20.549827 — systems biology — Posted on 2023-07-23
1283 Optimization of 3-Cyano-7-cyclopropylamino-pyrazolopyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2
Yang, X.; Ong, H. W.; Dickmander, R. J.; Smith, J. L.; Brown, J. W.; Tao, W.; Chang, E.; Moorman, N. J.; Axtman, A. D.; Willson, T. M.
10.1101/2023.05.15.540828 — pharmacology and toxicology — Posted on 2023-07-23
1284 Structural Basis for the Phase Separation of the Chromosome Passenger Complex
Bryan, N. W.; Ali, A.; Niedzialkowska, E.; Mayne, L.; Stukenberg, P. T.; Black, B. E.
10.1101/2023.05.22.541822 — biochemistry — Posted on 2023-07-23
1286 Loss of the mitochondrial citrate carrier, SLC25A1/CIC disrupts embryogenesis via 2-Hydroxyglutarate
Kasprzyk-Pawelec, A.; Tan, M.; Phua, Y.-L.; Rahhal, R.; McIntosh, A.; Fernandez, H.; Mosaoa, R.; Cheema, A.; Jiang, L.; Popratiloff, A.; Clarkson, C.; Pearson, G. W.; Glasgow, E.; Albanese, C.; Vockley, J.; Avantaggiati, M. L.
10.1101/2023.07.18.549409 — developmental biology — Posted on 2023-07-23
1291 Upregulated Fcrl5 disrupts B cell anergy and causes autoimmunity
Ono, C.; Tanaka, S.; Myouzen, K.; Iwasaki, T.; Ueda, M.; Oda, Y.; Yamamoto, K.; Kochi, Y.; Baba, Y.
10.1101/2023.07.20.549843 — immunology — Posted on 2023-07-23
1292 Protein interaction mapping reveals widespread targeting of development-related host transcription factors by phytoplasma effectors
Correa Marrero, M.; Capdevielle, S.; Huang, W.; Al-Subhi, A. M.; Busscher, M.; Busscher-Lange, J.; van der Wal, F.; de Ridder, D.; van Dijk, A. D. J.; Hogenhout, S. A.; Immink, R. G. H.
10.1101/2020.02.13.946517 — plant biology — Posted on 2023-07-23
1294 Translational regulation enhances distinction of cell types in the nervous system
Ichinose, T.; Kondo, S.; Kanno, M.; Shichino, Y.; Mito, M.; Iwasaki, S.; Tanimoto, H.
10.1101/2023.06.15.545207 — neuroscience — Posted on 2023-07-23
1296 The language network reliably 'tracks' naturalistic meaningful non-verbal stimuli
Sueoka, Y.; Paunov, A.; Ivanova, A.; Tanner, A.; Blank, I. A.; Fedorenko, E.
10.1101/2022.04.24.489316 — neuroscience — Posted on 2023-07-22
1298 Cost-effectiveness of Precision Guided SIT for Control of Anopheles gambiae in the Upper River Region, The Gambia.
Grendron, W.; Raban, R.; Mondal, A.; Sanchez C., H. M.; Smidler, A.; Zilberman, D.; Ilboudo, P. G.; D'Alessandro, U.; Marshall, J. M.; Akbari, O.
10.1101/2023.07.20.549762 — genetics — Posted on 2023-07-22
1300 A functional microbiome catalog crowdsourced from North American rivers
Borton, M. A.; McGivern, B. B.; Willi, K. R.; Woodcroft, B. J.; Mosier, A. C.; Bambakidis, T.; Singleton, D. M.; Liu, F.; Edirisinghe, J. N.; Faria, J. P.; Leleiwi, I.; Daly, R. A.; Goldman, A. E.; Wilkins, M. J.; Hall, E.; Pennacchio, C.; Roux, S.; Eloe-Fadrosh, E. A.; Sullivan, M. B.; Henry, C. S.; Wood-Charlson, E. M.; Ross, M. R.; Miller, C. S.; Crump, B. C.; Stegen, J.; Wrighton, K. C.
10.1101/2023.07.22.550117 — microbiology — Posted on 2023-07-22
1301 Assessing the effect of antibody responses on viral rebound dynamics in postnatally SHIV-infected infant Rhesus macaques
Mainou, E.; Berendam, S. J.; Obregon-Perko, V.; Uffman, E. A.; Phan, C. T.; Shaw, G. M.; Bar, K. J.; Conway, J. M.; Chan, C.; Chahroudi, A. M.; McCarthy, J.; Permar, S. R.; Silvestri, G.; Siliciano, R. F.; Silicano, J.; Fouda, G. J.; Fray, E. J.; Kumar, M. R.
10.1101/2023.07.22.550159 — immunology — Posted on 2023-07-22
1302 Contrasting roles of different mismatch repair proteins in basal-like breast cancer
Mo, J.; Borcherding, N.; Jo, S.; Tithi, T. I.; Cho, E.; Cash, C. E.; Honda, M.; Ahmed, K. K.; kolb, R.; Weigel, R.; Spies, M.; Zhang, W.
10.1101/2023.07.20.549745 — cancer biology — Posted on 2023-07-22
1303 Acetyl-CoA carboxylase 1-dependent lipogenesis drives breast cancer progression
Tan, K.; Owen, T.; McEwen, H. P.; Simpson, P.; Hoy, A. J.; James, D. E.; Don, A. S.; Naylor, M. J.
10.1101/2023.07.20.549828 — cancer biology — Posted on 2023-07-22
1306 Sequencing 4.3 million mutations in wheat promoters to understand and modify gene expression
Zhang, J.; Xiong, H.; Burguener, G. F.; Vasquez-Gross, H.; Liu, Q.; Debernardi, J. M.; Akhunova, A.; Campbell-Garland, K.; Kianian, S.; Brown-Guedira, G.; Pozniak, C.; Faris, J.; Akhunov, E.; Dubcovsky, J.
10.1101/2023.07.21.550110 — genomics — Posted on 2023-07-22
1307 Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function
K C, R.; Patel, N. R.; Shenoy, A.; Scallan, J.; Chiang, M.; Galazo, M. J.; Meadows, S. M.
10.1101/2023.07.22.550165 — molecular biology — Posted on 2023-07-22
1309 Large pilin subunits provide distinct structural and mechanical properties for the Myxococcus xanthus type IV pilus
Treuner-Lange, A.; Zheng, W.; Viljoen, A.; Lindow, S.; Herfurth, M.; Dufrene, Y. F.; Sogaard-Andersen, L.; Egelman, E.
10.1101/2023.07.22.550172 — microbiology — Posted on 2023-07-22
1314 PseudoCell: A collaborative network for in silico prediction of regulatory pathways
Pierdona, V.; Lavandoski, P.; Maurmann, R. M.; Borges, G. A.; Mombach, J. C. M.; Guma, F. T. C. R.; Barbe-Tuana, F. M.
10.1101/2023.07.20.549793 — bioinformatics — Posted on 2023-07-22
1315 Voyager: exploratory single-cell genomics data analysis with geospatial statistics
Moses, L.; Einarsson, P. H.; Jackson, K. C.; Luebbert, L.; Booeshaghi, A. S.; Antonsson, S. E.; Melsted, P.; Pachter, L.
10.1101/2023.07.20.549945 — bioinformatics — Posted on 2023-07-22
1318 Cryogenic Soft Landing Improves Structural Preservation of Protein Complexes
Westphall, M. S.; Lee, K.; Hemme, C.; Salome, A.; Mertz, K.; Grant, T.; Coon, J.
10.1101/2023.07.21.550105 — biochemistry — Posted on 2023-07-22
1320 The density of regulatory information is a major determinant of evolutionary constraint on non-coding DNA in Drosophila
Sabaris, G.; Ortiz, D. M.; Laiker, I.; Mayansky, I.; Naik, S.; Cavalli, G.; Stern, D. L.; Preger-Ben Noon, E.; Frankel, N.
10.1101/2023.07.21.550043 — genetics — Posted on 2023-07-22
1321 CTCF/cohesin organize the ground state of chromatin-nuclear speckle association
Yu, R.; Roseman, S.; Siegenfeld, A. P.; Nguyen, S. C.; Joyce, E. F.; Liau, B.; Krantz, I. D.; Alexander, K.; Berger, S. L.
10.1101/2023.07.22.550178 — genetics — Posted on 2023-07-22
1322 hnRNPUL1 ensures efficient Integrator-mediated cleavage of snRNAs and is mutated in amyotrophic lateral sclerosis
Yonchev, I. D.; Apostol, C. V.; Griffith, L.; Li, A.; Butler, L.; Patrick, H.; Aguilar-Martinez, E.; Whelan, A. G.; Evans, C.; Dickman, M. J.; Cooper-Knock, J.; Shaw, P. J.; West, S.; Barbaric, I.; Sudbery, I. M.; Wilson, S. A.
10.1101/2023.07.22.550030 — molecular biology — Posted on 2023-07-22
1323 Salmonella impairs macrophage immunity through effector-independent rapid translational induction in response to membrane puncture by the SPI-1 injectisome
Wood, G.; Powell, J.; Johnson, R.; Lastovka, F.; Bryant, O.; Brember, M.; Tourlomousis, P.; Carr, J.; Bryant, C.; Chung, B. Y.
10.1101/2023.07.21.550113 — molecular biology — Posted on 2023-07-22
1324 Chromosome organization shapes replisome dynamics in Caulobacter crescentus
Zhang, C.; Joseph, A. M.; Casini, L.; Collier, J.; Badrinarayanan, A.; Manley, S.
10.1101/2023.07.22.550130 — microbiology — Posted on 2023-07-22
1327 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E.; Baker, T. M.; Lesluyes, T.; Monlong, J.; Abe, K. T.; Coelho, P. P.; Schwartz, M.; Zou, D.; Morin, G.; Pacis, A.; Yang, Y.; Martinez, C.; Barber, J.; Kuasne, H.; Li, R.; Bourgey, M.; Fortier, A.-M.; Davison, P. G.; Omeroglu, A.; Guiot, M. C.; Morris, Q.; Kleinman, C. L.; Huang, S.; Gingras, A.-C.; Ragoussis, I.; Bourque, G.; Van Loo, P.; Park, M.
10.1101/2023.06.10.544434 — genomics — Posted on 2023-07-22
1328 Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
Ayoubi, R.; Ryan, J.; Biddle, M. S.; Alshafie, W.; Fotouhi, M.; Bolivar, S. G.; Moleon, V. R.; Eckmann, P.; Worrall, D.; McDowell, I.; Southern, K.; Reintsch, W.; Durcan, T. M.; Brown, C. M.; Bandrowski, A. E.; Virk, H. S.; Edwards, A. M.; McPherson, P. S.; Laflamme, C.
10.1101/2023.06.01.543292 — molecular biology — Posted on 2023-07-22
1330 Species-aware DNA language models capture regulatory elements and their evolution
Karollus, A.; Hingerl, J.; Gankin, D.; Grosshauser, M.; Klemon, K.; Gagneur, J.
10.1101/2023.01.26.525670 — bioinformatics — Posted on 2023-07-22
1331 Direct Assessment of Nitrative Stress in Lipid Environments: Applications of a Designer Lipid-Based Biosensor for Peroxynitrite
Gutierrez, B.; Aggarwal, T.; Erguven, H.; Stone, M. R. L.; Guo, C.; Alyssa Bellomo, A.; Abramova, E.; Stevenson, E.; Gow, A.; Izgu, E. C.
10.1101/2022.06.22.497268 — biochemistry — Posted on 2023-07-22
1332 Whole-genome sequencing across 449 samples spanning 47 ethnolinguistic groups provides insights into genetic diversity in Nigeria
Joshi, E.; Biddanda, A.; Popoola, J.; Yakubu, A.; Osakwe, O.; Attipoe, D.; 54gene Team, ; NCD-GHS Consortium, ; Dogbo, E.; Salako, B.; Nash, O.; Salako, O.; Oyedele, O.; Eze-Echesi, G.; Fatumo, S.; Ene-Obong, A.; O'Dushlaine, C.
10.1101/2022.12.09.519178 — genomics — Posted on 2023-07-22
1333 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep
Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.
10.1101/2023.07.21.550073 — ecology — Posted on 2023-07-22
1334 Five inhibitory receptors display distinct vesicular distributions in T cells
Lu, J.; Veler, A.; Simonetti, B.; Raj, T.; Chou, P. H.; Cross, S. J.; Phillips, A. M.; Ruan, X. J.; Huynh, L.; Dowsey, A. W.; Ye, D.; Murphy, R. F.; Verkade, P.; Cullen, P. J.; Wuelfing, C.
10.1101/2023.07.21.550019 — immunology — Posted on 2023-07-22
1336 Molecular responses of agroinfiltrated Nicotiana benthamiana leaves expressing suppressor of silencing P19 and influenza virus-like particles
Hamel, L.-P.; Tardif, R.; Poirier-Gravel, F.; Rasoolizadeh, A.; Brosseau, C.; Giroux, G.; Lucier, J.-F.; Goulet, M.-C.; Barrada, A.; Roussel, E.; Comeau, M.-A.; Lavoie, P.-O.; Moffett, P.; Michaud, D.; D Aoust, M.-A.
10.1101/2023.07.21.550062 — plant biology — Posted on 2023-07-22
1340 Season-dependent processing of innate conspecific vocalizations in the male and female European starling (Sturnus vulgaris)
Vidas-Guscic, N. D.; Jonckers, E.; Van Audekerke, J.; Orije, J.; Hamaide, J.; Majumdar, G.; Verhoye, M.; Van der Linden, A.
10.1101/2023.07.20.549888 — neuroscience — Posted on 2023-07-22
1342 Predicting the Beat Bin - Beta Oscillations Support Top-Down Prediction of the Temporal Precision of a Rhythmic Event
Leske, S.; Endestad, T.; Volehaugen, V.; Foldal, M. D.; Blenkmann, A. O.; Solbakk, A.-K.; Danielsen, A.
10.1101/2023.07.21.550020 — neuroscience — Posted on 2023-07-22
1343 A paradigm for ethanol consumption in head-fixed mice during prefrontal cortical two-photon calcium imaging
Kalelkar, A.; Sipe, G. O.; Castro E Costa, A. R.; Lorenzo, I. M.; Nguyen, M.; Linares-Garcia, I.; Vazey, E.; Huda, R.
10.1101/2023.07.20.549846 — neuroscience — Posted on 2023-07-22
1344 Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature
Zane, F.; Bouzid, H.; Sosa Marmol, S.; Brazane, M.; Besse, S.; Molina, J. L.; Cansell, C.; Aprahamian, F.; Durand, S.; Ayache, J.; Antoniewski, C.; Todd, N.; Rera, M.
10.1101/2022.11.22.517330 — systems biology — Posted on 2023-07-22
1345 A temperature-controlled, circular maintenance system for studying growth and development of pelagic tunicates (Salps)
Mueller, S. J.; Wessels, W.; Driscoll, S.; Pakhomov, E. A.; Auerswald, L.; Michael, K.; Meyer, B.
10.1101/2023.07.21.547827 — physiology — Posted on 2023-07-22
1346 Dermonecrosis caused by spitting cobra snakebite is the result of toxin potentiation and is prevented by the repurposed drug varespladib
Bartlett, K. E.; Hall, S. R. R.; Rasmussen, S. A.; Crittenden, E.; Dawson, C. A.; Albulescu, L.-O.; Laprade, W. M.; Harrison, R. A.; Saviola, A. J.; Jenkins, T. P.; Wilkinson, M. C.; Gutierrez, J. M.; Casewell, N. R.
10.1101/2023.07.20.549878 — pharmacology and toxicology — Posted on 2023-07-22
1347 PANDORA v2.0: Benchmarking peptide-MHC II models and software improvements
Parizi, F. M.; Marzella, D. F.; Ramakrishnan, G.; 't Hoen, P. A. C.; Karimi-Jafari, M. H.; Xue, L. C.
10.1101/2023.07.20.549892 — bioinformatics — Posted on 2023-07-22
1350 An mTOR/RNA pol I axis shapes chromatin architecture in response to fasting
Al-Refaie, N.; Padovani, F.; Binando, F.; Hornung, J.; Zhao, Q.; Towbin, B. D.; Sarinay Cenik, E.; Stroustrup, N.; Schmoller, K. M.; Cabianca, D. S.
10.1101/2023.07.22.550032 — cell biology — Posted on 2023-07-22
1352 Modeling Human Spine-Spinal Cord Organogenesis by hPSC-Derived Neuromesodermal Progenitors
Li, D.; Ma, Y.; Huang, W.; Li, X.; Liu, H.; Xiong, C.; Zhao, Q.; Wang, B.; Huang, S.; Wei, Y.; Chen, J.; Lai, X.; Zhang, X.; Wei, L.; Ye, W.; Chen, Q.; Rong, L.; Xiang, A. P.; Li, W.
10.1101/2023.07.20.549829 — developmental biology — Posted on 2023-07-22
1357 Extracting herbicide and antibiotic natural products from a plant-microbe interaction system
Pan, S.; Li, X.; Pan, C.; Li, J.; Fan, S.; Zhang, L.; Du, K.; Du, Z.; Zhang, J.; Huang, H.; Li, J.; Zhang, H.; Huang, J.; Qin, Z.
10.1101/2023.07.22.550126 — cell biology — Posted on 2023-07-22
1358 Commentary on Pang et al. (2023) Nature
Faskowitz, J.; Moyer, D.; Handwerker, D.; Gonzalez-Castillo, J.; Bandettini, P.; Jbabdi, S.; Betzel, R.
10.1101/2023.07.20.549785 — neuroscience — Posted on 2023-07-22
1359 Characterization and diversification of AraC/XylS family regulators guided by transposon sequencing
Pearson, A. N.; Incha, M. R.; Ho, C.; Schmidt, M.; Roberts, J. B.; Nava, A. A.; Keasling, J. D.
10.1101/2023.07.21.550116 — synthetic biology — Posted on 2023-07-22
1360 Microbial biosensor for sensing and treatment of intestinal inflammation
Zhu, D.; Galley, J. D.; Pizzini, J.; Musteata, E.; Tabor, J. J.; Britton, R. A.
10.1101/2023.07.21.550106 — synthetic biology — Posted on 2023-07-22
1361 CRISPR/Cas9 screenings unearth protein arginine methyltransferase 7 as a novel driver of metastasis in prostate cancer
Rodrigo-Faus, M.; Vincelle-Nieto, A.; Vidal, N.; Puente, J.; Saiz-Pardo, M.; Lopez-Garcia, A.; Mendiburu-Elicabe, M.; Palao, N.; Baquero, C.; Cuesta, A. M.; Qu, H.-Q.; Hakonarson, H.; Musteanu, M.; Reyes-Palomares, A.; Porras, A.; Bragado, P.; Gutierrez-Uzquiza, A.
10.1101/2023.07.20.549704 — cancer biology — Posted on 2023-07-22
1365 Visible light-induced specific protein reaction delineates early stages of cell adhesion
Rahikainen, R.; Vester, S. K.; Turkki, P.; Janosko, C.; Deiters, A.; Hytonen, V. P.; Howarth, M.
10.1101/2023.07.21.549850 — synthetic biology — Posted on 2023-07-22
1366 Slow-wave brain connectivity predicts executive functioning and group belonging in socially vulnerable individuals
Lanfranco, R. C.; dos Santos Sousa, F.; Wessel, P. M.; Rivera-Rei, A.; Bekinschtein, T.; Lucero, B.; Canales-Johnson, A.; Huepe, D.
10.1101/2023.07.19.549808 — neuroscience — Posted on 2023-07-22
1368 Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence
Tabata, S.; Matsuda, K.; Nagai, K.; Izumi, Y.; Takahashi, M.; Motomura, Y.; Nagasato, A. I.; Shimma, S.; Moro, K.; Bamba, T.; Okada, M.
10.1101/2023.04.18.536673 — systems biology — Posted on 2023-07-21
1370 Pathogen community composition and co-infection patterns in a wild community of rodents
Abbate, J. L.; Galan, M.; Razzauti, M.; Sironen, T.; Voutilainen, L.; Henttonen, H.; Gasqui, P.; Cosson, J.-F.; Charbonnel, N.
10.1101/2020.02.09.940494 — ecology — Posted on 2023-07-21
1376 Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing
Ackerman, J. E.; Adjei-Sowah, E.; Korcari, A.; Muscat, S. N.; Nichols, A. E.; Buckley, M. R.; Loiselle, A. E.
10.1101/2023.07.21.550090 — cell biology — Posted on 2023-07-21
1379 Generation of an induced pluripotent stem cell line from a healthy adult indigenous Nigerian participant
Muhammad, Z.; Brown, P. W.; Babazau, L.; Alkhamis, A. I.; Goni, B. W.; Nggada, H. A.; Mbaya, K. M.; Wray, S.; Marte, I. H.; Karch, C.; Serpell, L.; Maina, M. B.
10.1101/2023.07.21.550059 — cell biology — Posted on 2023-07-21
1380 Retinal energy metabolism: Photoreceptors switch between Cori, Cahill, and mini-Krebs cycles to uncouple glycolysis from mitochondrial respiration
Chen, Y.; Zizmare, L.; Calbiague, V.; Wang, L.; Yu, S.; Herberg, F. W.; Schmachtenberg, O.; Paquet-Durand, F.; Trautwein, C.
10.1101/2022.06.20.496788 — cell biology — Posted on 2023-07-21
1381 ISGylation-independent protection of cell growth by USP18 following interferon stimulation
Clancy, A.; Rusilowicz-Jones, E. V.; Wallace, I.; Swatek, K. N.; Urbe, S.; Clague, M. J.
10.1101/2023.07.21.549904 — cell biology — Posted on 2023-07-21
1382 Design principles of Cdr2 node patterns in fission yeast cells
Opalko, H. E.; Geng, S.; Hall, A. R.; Vavylonis, D.; Moseley, J. B.
10.1101/2023.04.19.537536 — cell biology — Posted on 2023-07-22
1383 Shared functional specialization in transformer-based language models and the human brain
Kumar, S.; Sumers, T. R.; Yamakoshi, T.; Goldstein, A.; Hasson, U.; Norman, K. A.; Griffiths, T. L.; Hawkins, R. D.; Nastase, S. A.
10.1101/2022.06.08.495348 — neuroscience — Posted on 2023-07-21
1384 Nonlinear manifolds underlie neural population activity during behaviour
Fortunato, C.; Bennasar-Vazquez, J.; Park, J.; Chang, J. C.; Miller, L. E.; Dudman, J. T.; Perich, M. G.; Gallego, J. A.
10.1101/2023.07.18.549575 — neuroscience — Posted on 2023-07-21
1386 Mega-Enhancer Bodies Organize Neuronal Long Genes in the Cerebellum
Zhao, Z.; Parra, O. P.; Muscella, F.; Scrutton-Alvarado, N.; Fujita, S.-i.; Alber, F.; Yang, Y.; Yamada, T.
10.1101/2023.07.19.549737 — neuroscience — Posted on 2023-07-21
1389 Growth/differentiation factor 15 controls number of ependymal and neural stem cells in the ventricular-subventricular zone
Baur, K.; Carrillo Garcia, C.; San, S.; von Hahn, M.; Strelau, J.; Hölzl-Wenig, G.; Mandl, C.; Ciccolini, F.
10.1101/2022.12.02.518869 — neuroscience — Posted on 2023-07-22
1391 Therapy-induced normal tissue damage promotes breast cancer metastasis
Perkins, D. W.; Steiner, I.; Haider, S.; Roberston, D.; Buus, R.; O'Leary, L.; Isacke, C. M.
10.1101/2020.10.17.343590 — cancer biology — Posted on 2023-07-21
1393 Substrate evaporation drives collective construction in termites
Facchini, G.; Rathery, A.; Douady, S.; Sillam-Dusses, D.; Perna, A.
10.1101/2023.02.17.528984 — biophysics — Posted on 2023-07-21
1395 Learning from the unknown: exploring the range of bacterial functionality
Mahlich, Y.; Zhu, C.; Chung, H.; Velaga, P. K.; de Paolis Kaluza, M. C.; Radivojac, P.; Friedberg, I.; Bromberg, Y.
10.1101/2022.11.28.518265 — bioinformatics — Posted on 2023-07-21
1396 RNA structure landscape of S. cerevisiae introns
Rangan, R.; Huang, R.; Hunter, O.; Pham, P.; Ares, M.; Das, R.
10.1101/2022.07.22.501175 — biochemistry — Posted on 2023-07-21
1399 Structured demographic buffering: A framework to explore the environment drivers and demographic mechanisms underlying demographic buffering
Gascoigne, S. J. L.; Kajin, M.; Tuljapurkar, S. D.; Santos, G. S.; Compagnoni, A.; Steiner, U. K.; Vinton, A. C.; Jaggi, H.; Sepil, I.; Salguero-Gomez, R.
10.1101/2023.07.20.549848 — ecology — Posted on 2023-07-21
1400 Waddington Revisited: Organ transformation by environmental disruption of epigenetic memory
Snir, O.; Elgart, M.; Ciabrelli, F.; Dagan, S.; Aviezer, I.; Stoops, E.; Cavalli, G.; Soen, Y.
10.1101/482216 — developmental biology — Posted on 2023-07-21
1405 Cell division angle regulates the tissue mechanics and tunes the amount of cerebellar folding
Cook, A. G.; Bishop, T. V.; Crowe, H. R.; Stevens, D. N.; Reine, L.; Joyner, A. L.; Lawton, A. K.
10.1101/2023.07.21.549165 — developmental biology — Posted on 2023-07-21
1408 Identification and Characterization of Calcium Binding Protein, Spermatid Associated 1 (CABS1) in Selected Human Tissues and Fluids
Reyes-Serratos, E.; Santos, J. R. L.; Puttagunta, L.; Lewis, S.; Watanabe, M.; Gonshor, A.; Buck, R.; Befus, A. D.; Marcet-Palacios, M.
10.1101/2023.07.21.550040 — cell biology — Posted on 2023-07-21
1413 Predicting Gene Spatial Expression and Cancer Prognosis: An Integrated Graph and Image Deep Learning Approach Based on HE Slides
Gao, R.; Yuan, X.; Ma, Y.; Wei, T.; Johnston, L.; Shao, Y.; Lv, W.; Zhu, T.; Zhang, Y.; Zheng, J.; Chen, G.; Sun, J.; Wang, Y. G.; Yu, Z.
10.1101/2023.07.20.549824 — bioinformatics — Posted on 2023-07-21
1416 Chromosome-scale genome assembly of Tinospora sagittata (Oliv.) Gagnep. enhances identifying genes involved in the biosynthesis of jatrorrhizine
Alami, M. M.; Shu, S.; Liu, S.; Ouyang, Z.; Zhang, Y.; Lv, M.; Sang, Y.; Gong, D.; Yang, G.; Feng, S.; Mei, Z.; Xie, D.-Y.; Wang, X.
10.1101/2023.07.20.549971 — genomics — Posted on 2023-07-21
1418 Ethanol Drives Evolution of Hsp90-Dependent Robustness by Redundancy in Yeast Domestication
Patel, D.; Amiji, H.; Shropshire, W.; Condic, N.; Ozirmak Lermi, N.; Sabha, Y.; John, B.; Hanson, B.; Karras, G. I.
10.1101/2023.07.21.547572 — evolutionary biology — Posted on 2023-07-21
1420 Autophagy maintains the homeostatic environment in the male reproductive accessory organs playing a key role in fertility
Jaulim, A.; Cassidy, L. D.; Young, A. R. J.; Chan, A. S. L.; Warren, A. Y.; Taylor, A. E.; Arlt, W.; Lan, G.; Blayney, M. L.; Davidson, O.; Barratt, C. L. R.; Pacey, S.; Narita, M.
10.1101/2023.07.21.549845 — cell biology — Posted on 2023-07-21
1421 Large-scale deep tissue voltage imaging with targeted illumination confocal microscopy
Xiao, S.; Cunningham, W. J.; Kondabolu, K.; Lowet, E.; Moya, M. V.; Mount, R.; Ravasio, C.; Economo, M. N.; Han, X.; Mertz, J.
10.1101/2023.07.21.548930 — neuroscience — Posted on 2023-07-21
1422 Membrane mechanics dictate axonal morphology and function
Griswold, J. M.; Bonilla-Quintana, M.; Pepper, R.; Lee, C. T.; Raychaudhuri, S.; Ma, S.; Gan, Q.; Syed, S.; Zhu, C.; Bell, M.; Suga, M.; Yamaguchi, Y.; Chereau, R.; Nagerl, V.; Knott, G. W.; Rangamani, P.; Watanabe, S.
10.1101/2023.07.20.549958 — neuroscience — Posted on 2023-07-21
1423 LEF1 isoforms regulate cellular senescence and aging
Jia, M.; Sayed, K.; Kapetanaki, M. G.; Dion, W.; Rosas, L.; Irfan, S.; Valenzi, E.; Mora, A. L.; Lafyatis, R. A.; Rojas, M.; Zhu, B.; Benos, P. V.
10.1101/2023.07.20.549883 — genomics — Posted on 2023-07-21
1424 Genome Sequence and Annotation the B3 Mycobacteriophage Phayeta
Bishop, E. E.; Earley, W. K.; Greco, A. M.; Hofseth, E. M.; Kinerson, E. E.; Lafayette, B. D.; Llanot-Arocho, N. J.; Mazen, B. M.; Cevasco, M.; Williams, D. C.
10.1101/2023.07.21.550035 — genomics — Posted on 2023-07-21
1425 High performance enrichment-based genome sequencing to support the investigation of hepatitis A virus outbreaks
Zufan, S. E.; Mercoulia, K.; Kwong, J.; Judd, L. M.; Howden, B. P.; Seemann, T.; Stinear, T. P.
10.1101/2023.07.21.548488 — genomics — Posted on 2023-07-21
1426 A small RNA from a natural bacterial pathogen of C. elegans induces transgenerational inheritance of learned avoidance
Sengupta, T.; Ange, J. S.; Moore, R. S.; Kaletsky, R. T.; Marogi, J. T.; Myhrvold, C.; Gitai, Z.; Murphy, C. T.
10.1101/2023.07.20.549962 — genetics — Posted on 2023-07-21
1427 Integrative determination of the atomic structure of mutant huntingtin exon 1 fibrils from Huntington's disease
Bagherpoor Helabad, M.; Matlahov, I.; Daldrop, J. O.; Jain, G.; van der Wel, P. C. A.; Miettinen, M. S.
10.1101/2023.07.21.549993 — molecular biology — Posted on 2023-07-21
1432 Eliminating Malaria Vectors with Precision Guided Sterile Males
Smidler, A. L.; Apte, R. A.; Pai, J. J.; Chow, M. L.; Chen, S.; Mondal, A.; Sanchez C., H. M.; Antoshechkin, I.; Marshall, J. M.; Akbari, O. S.
10.1101/2023.07.20.549947 — bioengineering — Posted on 2023-07-21
1434 Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates
Greyling, N.; van der Watt, M.; Gwarinda, H.; van Heerden, A.; Greenhouse, B.; Leroy, D.; Niemand, J.; Birkholtz, L.-M.
10.1101/2023.07.20.549807 — biochemistry — Posted on 2023-07-21
1436 Expanding the Substrate Scope of N- and O-Methyltransferases from Plants for Chemoselective Alkylation
Jockmann, E.; Subrizi, F.; Mohr, M. K. F.; Carter, E. M.; Hebecker, P. M.; Popadic, D.; Hailes, H. C.; Andexer, J. N.
10.1101/2023.07.21.549995 — biochemistry — Posted on 2023-07-21
1437 Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli
Xu, Z.-Q.; Jergic, S.; Lo, A. T. Y.; Pradhan, A. C.; Brown, S. H. J.; Bouwer, J. C.; Ghodke, H.; Lewis, P. J.; Tolun, G.; Oakley, A. J.; Dixon, N. E.
10.1101/2023.07.20.549978 — biochemistry — Posted on 2023-07-21
1438 Cas9-directed long-read sequencing to resolve optical genome mapping findings in leukemia diagnostics.
de Boer, E. N.; Vroom, V.; Scheper, A. J.; Johansson, L. F.; Bosscher, L.; Rietema, N.; Commandeur, S. Z.; Knoers, N. V. A. M.; Sikkema-Raddatz, B.; Berg, E. v. d.; van Diemen, C. C.
10.1101/2023.07.21.549991 — genetics — Posted on 2023-07-21
1439 Unravelling the novel genetic diversity and marker-trait associations of corn leaf aphid resistance in wheat using microsatellite markers
Yadav, J.; Jasrotia, P.; Jaglan, M. S.; Sareen, S.; Kashyap, P. L.; Yadav, S. K.; Kumar, S.; Singh, G.; Singh, G. P.
10.1101/2023.07.21.550056 — molecular biology — Posted on 2023-07-21
1442 Structure of a tripartite protein complex that targets toxins to the type VII secretion system
Klein, T. A.; Shah, P. Y.; Gkragkopoulou, P.; Grebenc, D. W.; Kim, Y.; Whitney, J. C.
10.1101/2023.07.21.550046 — microbiology — Posted on 2023-07-21
1443 Parallel evolution and enhanced virulence upon in vivo passage of an RNA virus in Drosophila melanogaster
Lezcano, O. M.; Fuhrmann, L.; Ramakrishnan, G.; Beerenwinkel, N.; Huynen, M.; van Rij, R. P.
10.1101/2023.07.21.549997 — microbiology — Posted on 2023-07-21
1445 Autophagy restricts fungal accommodation in the roots ofArabidopsis thaliana
Zecua-Ramirez, P.; Llamas, E.; Charura, N.; Dunken, N.; De Quattro, C.; Mandel, A.; Langen, G.; Dagdas, Y.; Zuccaro, A.
10.1101/2023.07.21.550010 — microbiology — Posted on 2023-07-21
1446 Distinct composition of plasma virome in HIV-infected subjects on antiretroviral therapy compared to controls
Bhagchandani, T.; Haque, M. M. U.; Malik, M. Z.; Ray, A. K.; S, U. K.; Rai, A.; Verma, A.; Sawlani, K. K.; Chaturvedi, R.; D, H.; Tandon, R.
10.1101/2023.07.21.548740 — microbiology — Posted on 2023-07-21
1448 An oxadiazole-based compound potentiates anti- tuberculosis treatment by increasing host resistance via zinc poisoning
Maure, A.; Lawaree, E.; Fiorentino, F.; Pawlik, A.; Gona, S.; Giraud-Gatineau, A.; Eldridge, M. J. G.; Danckaert, A.; Hardy, D.; Frigui, W.; Keck, C.; Aulner, N.; Mai, A.; Hamon, M.; Barreiro, L. B.; Brodin, P.; Brosch, R.; Rotili, D.; Tailleux, L.
10.1101/2023.07.21.549986 — microbiology — Posted on 2023-07-21
1449 Macrophage Xanthine Oxidoreductase Links LPS Induced Lung Inflammatory Injury to NLRP3 Inflammasome Expression and Mitochondrial Respiration
Fini, M. A.; Monks, J. A.; Li, M.; Gerasimovskaya, E.; Paucek, P.; Wang, K.; Frid, M. G.; Pugliese, S. C.; Bratton, D.; Yu, Y.-R.; Irwin, D.; Karin, M.; Wright, R. M.; Stenmark, K. R.
10.1101/2023.07.21.550055 — immunology — Posted on 2023-07-21
1450 Visible light-induced specific protein reaction delineates early stages of cell adhesion
Howarth, M.; Rahikainen, R.; Vester, S. K.; Turkki, P.; Janosko, C.; Deiters, A.; Hytonen, V. P.
10.1101/2023.07.21.549850 — synthetic biology — Posted on 2023-07-21
1451 Hidden Markov Models based search in combination with structural bioinformatics pipeline leads to the identification of DAF-12 distant orthologous in Meloidogyne incognita
Schuster, C. D.; Zabala, V. J. S.; San Juan, R. B.; Sosa, E. J.; Rodriguez, C.; Kronberg, M. F.; Munarriz, E. R.; Burton, G.; Castro, O. A.; Modenutti, C. P.
10.1101/2023.07.19.549723 — bioinformatics — Posted on 2023-07-21
1453 Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA
Reddy, N. A.; Zvolanek, K. M.; Moia, S.; Caballero-Gaudes, C.; Bright, M. G.
10.1101/2023.07.19.549746 — neuroscience — Posted on 2023-07-21
1454 Mega-Enhancer Bodies Organize Neuronal Long Genes in the Cerebellum
Zhao, Z.; Parra, O. P.; Muscella, F.; Alber, F.; Scrutton-Alvarado, N.; Muscella, F.; Yang, Y.; Yamada, T.
10.1101/2023.07.19.549737 — neuroscience — Posted on 2023-07-21
1456 Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas
Fordham, A. M.; Brown, L. M.; Mayoh, C.; Salib, A.; Barger, Z. A.; Wong, M.; Sian, T. C. C. L. K.; Xie, J.; Gunther, K.; Trebilcock, P.; Terry, R. L.; Barahona, P.; Ajuyah, P.; Sherstyuk, A.; Avila, A.; Cadiz, R.; Perkins, C. M.; Gifford, A. J.; Mao, J.; Zhao, A.; O'Regan, L. P.; Gorgels, D.; Lau, L. M.; Ziegler, D. S.; Haber, M.; Tyrrell, V.; Lock, R. B.; Cowley, M.; Nicholls, W.; Daly, R. J.; Ekert, P. G.; Fleuren, E. D.
10.1101/2023.07.19.548825 — cancer biology — Posted on 2023-07-21
1457 CBD and PSP cell-passaged Tau Seeds Generate Heterogeneous Fibrils with A Subpopulation Adopting Disease Folds
Zeng, Z.; Vijayan, V.; Tsay, K.; Frost, M.; Quddus, A.; Albert, A.; Vigers, M.; Woerman, A.; Han, S.
10.1101/2023.07.19.549721 — biophysics — Posted on 2023-07-21
1458 Flow in fetoplacental microvessels in vitro enhances perfusion, barrier function, and matrix stability
Cherubini, M.; Erickson, S.; Padmanaban, P.; Haberkant, P.; Stein, F.; Sastre, V. B.; Haase, K.
10.1101/2023.07.19.549736 — bioengineering — Posted on 2023-07-21
1460 Individuals lack the capacity to accurately detect emotional piloerection
McPhetres, J.; Han, A.; Gao, H. H.; Kemp, N.; Khati, B.; Pu, C. X.; Smith, A.; Shui, X.
10.1101/2023.07.19.549671 — animal behavior and cognition — Posted on 2023-07-21
1461 BL-Hi-C reveals the 3D genome structure of Brassica crops with high efficiency and sensitivity
Zhang, L.; Zhao, R.; Liang, J.; cai, x.; zhang, l.; guo, h.; zhang, z.; Wu, J.; Wang, X.
10.1101/2023.07.19.549753 — genomics — Posted on 2023-07-21
1462 Epigenetic features of far northern Yakutian population
Kalyakulina, A.; Yusipov, I.; Kondakova, E.; Bacalini, M. G.; Giuliani, C.; Sivtseva, T.; Semenov, S.; Ksenofontov, A.; Nikolaeva, M.; Khusnutdinova, E.; Zakharova, R.; Vedunova, M.; Franceschi, C.; Ivanchenko, M.
10.1101/2023.07.19.549706 — genetics — Posted on 2023-07-21
1464 Chronic striatal cholinergic interneuron excitation induces clinically-relevant dystonic behavior in mice
Gemperli, K.; Lu, X.; Chintalapati, K.; Rust, A.; Bajpai, R.; Suh, N.; Blackburn, J.; Gelineau-Morel, R.; Kruer, M. C.; Mingbunjerdsuk, D.; O'Malley, J.; Tochen, L.; Waugh, J.; Wu, S.; Feyma, T.; Perlmutter, J.; Mennerick, S.; McCall, J. G.; Aravamuthan, B. R.
10.1101/2023.07.19.549778 — neuroscience — Posted on 2023-07-21
1465 Slow-wave brain connectivity predicts executive functioning and group belonging in socially vulnerable individuals
Lanfranco, R. C.; dos Santos Sousa, F.; Wessel, P. M.; Rivera-Rei, A.; Bekinschtein, T.; Lucero, B.; Canales-Johnson, A.; Huepe, D.
10.1101/2023.07.19.549808 — neuroscience — Posted on 2023-07-21
1469 The Brain Electroencephalogram Microdisplay for Precision Neurosurgery
Tchoe, Y.; Wu, T.; U, H. S.; Roth, D. M.; Kim, D.; Lee, J.; Cleary, D. R.; Pizarro, P.; Tonsfeldt, K. J.; Lee, K.; Chen, P. C.; Bourhis, A. M.; Galton, I.; Coughlin, B.; Yang, J. C.; Paulk, A. C.; Halgren, E.; Cash, S. S.; Dayeh, S. A.
10.1101/2023.07.19.549735 — neuroscience — Posted on 2023-07-21
1470 Electromyographic Correlates of Effortful Listening in the Vestigial Auriculomotor System
Schroeer, A.; Corona-Strauss, F. I.; Hannemann, R.; Hackley, S. A.; Strauss, D. J.
10.1101/2023.07.19.549747 — neuroscience — Posted on 2023-07-21
1472 The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons
Russo, T.; Kolisnyk, B.; BS, A.; Kim, T. W.; Martin, J.; Plessis-Belair, J.; Ni, J.; Pearson, J. A.; Park, E. J.; Sher, R. B.; Studer, L.; Riessland, M.
10.1101/2023.07.19.549710 — neuroscience — Posted on 2023-07-21
1473 Pupil size reveals arousal level dynamics in human sleep
Carro-Dominguez, M.; Huwiler, S.; Oberlin, S.; Oesch, T. L.; Badii, G.; Lüthi, A.; Wenderoth, N.; Meissner, S. N.; Lustenberger, C.
10.1101/2023.07.19.549720 — neuroscience — Posted on 2023-07-21
1475 Expectancy-related changes in firing of dopamine neurons depend on hippocampus
Takahashi, Y.; Zhang, Z.; Montesinos-Cartegena, M.; Kahnt, T.; Langdon, A.; Schoenbaum, G.
10.1101/2023.07.19.549728 — neuroscience — Posted on 2023-07-21
1476 Non-canonical function of folate/folate receptor 1 during neural tube formation
Balashova, O. A.; Panoutsopoulos, A. A.; Visina, O.; Selhub, J.; Knoepfler, P.; Borodinsky, L. N.
10.1101/2023.07.19.549718 — neuroscience — Posted on 2023-07-21
1477 MiR-324-5p regulates the structure of dendritic spines and is essential for hippocampal long-term potentiation
Parkins, E. V.; Brager, D. H.; Rymer, J. K.; Burwinkel, J. M.; Rojas, D.; Tiwari, D.; Hu, Y.-C.; Gross, C.
10.1101/2023.07.19.549725 — neuroscience — Posted on 2023-07-21
1478 Novel insights into hippocampal perfusion using high-resolution, multi-modal 7T MRI
Haast, R. A.; Kashyap, S.; Ivanov, D.; Yousif, M. D.; DeKraker, J.; Poser, B. A.; Khan, A. R.
10.1101/2023.07.19.549533 — neuroscience — Posted on 2023-07-21
1480 Double Imprinted Nanoparticles for Sequential Membrane-to-Nuclear Drug Delivery
Singla, P.; Broughton, T.; Sullivan, M. V.; Garg, S.; Palmini, R. B.; Gupta, P.; Canfarotta, F.; Turner, N. W.; Velliou, E.; Amarnath, S.; Peeters, M.
10.1101/2023.07.19.549711 — cancer biology — Posted on 2023-07-21
1484 Identification of cambium stem cell factors and their positioning mechanism
Eswaran, G.; Rutten, J. P.; Han, J.; Iida, H.; Lopez Ortiz, J.; Makila, R.; Wybouw, B.; Vainio, L.; Porcher, A.; Leal Gavarron, M.; Zhang, J.; Blomster, T.; Wang, X.; Dolan, D. W. P.; Smetana, O.; Brady, S.; Kucukoglu Topcu, M.; ten Tusscher, K. H.; Etchells, P.; Mahonen, A. P.
10.1101/2023.07.20.549889 — plant biology — Posted on 2023-07-21
1485 Cardiomyocyte mechanical memory is regulated through the talin interactome and DLC1 dependent regulation of RhoA
Marhuenda, E.; Xanthis, I.; Pandey, P.; Azad, A.; Richter, M.; Pavlovic, D.; Gehmlich, K.; Faggian, G.; Ehler, E.; Levitt, J.; Ameer-Beg, S.; Iskratsch, T.
10.1101/2023.07.19.549635 — cell biology — Posted on 2023-07-21
1488 Pneumococcus suppresses host inflammatory response through COMMD2 mediated NF-κB degradation by aggrephagy
Connor, M. G.; Sanchez, L.; Chevalier, C.; Carvalho, F.; Eldridge, M. J. G.; Chaze, T.; Matondo, M.; Weight, C.; Dufour, S.; Impens, F.; Baumgarten, S.; Enninga, J.; Hamon, M. A.
10.1101/2022.04.08.487599 — microbiology — Posted on 2023-07-21
1492 Label-free ghost cytometry for manufacturing of cell therapy products
Teranishi, K.; Wagatsuma, K.; Toda, K.; Nomaru, H.; Yanagihashi, Y.; Ochiai, H.; Akai, S.; Mochizuki, E.; Onda, Y.; Nakagawa, K.; Sugimoto, K.; Takahashi, S.; Yamaguchi, H.; Ota, S.
10.1101/2023.07.09.545884 — cell biology — Posted on 2023-07-21
1493 Spliceosomal complex components are critical for adjusting the C:N balance during high-light acclimation
Araguirang, G. E.; Venn, B.; Kelber, N.-M.; Feil, R.; Lunn, J. E.; Kleine, T.; Leister, D.; Muehlhaus, T.; Richter, A. S.
10.1101/2023.07.19.549727 — molecular biology — Posted on 2023-07-21
1494 Dearth of smoking-induced mutations in NSRO-driven non-small-cell lung cancer despite smoking exposure
Huang, C.-Y.; Jiang, N.; Shen, M.; Lai, G.; Tan, A. C.; Jain, A.; Saw, S. P.; Ang, M.-K.; Ng, Q. S.; Lim, D. W.-T.; Kanesvaran, R.; Tan, E.-H.; Tan, W. L.; Ong, B.-H.; Chua, K. L.; Anantham, D.; Takano, A.; Lim, T. K. H.; Tam, W. L.; Sim, N. L.; Sanderup, A. J.; Tan, D. S. W.; Rozen, S. G.
10.1101/2023.07.04.547310 — cancer biology — Posted on 2023-07-21
1499 Protein semisynthesis underscores role of a conserved lysine in activation and desensitization of acid-sensing ion channels
Sarkar, D.; Galleano, I.; Heusser, S. A.; Ou, S. Y.; Uzun, G. R.; Khoo, K. K.; van Noort, G. J. v. d. H.; Harrison, J. S.; Pless, S. A.
10.1101/2023.01.23.525296 — biophysics — Posted on 2023-07-21
1503 Complexity and dynamics of in organello translation landscape assessed by high-resolution mitochondrial ribosome profiling
Wakigawa, T.; Mito, M.; Yamashiro, H.; Tomuro, K.; Tomizawa, K.; Chujo, T.; Nagao, A.; Suzuki, T.; Wei, F.-Y.; Shichino, Y.; Suzuki, T.; Iwasaki, S.
10.1101/2023.07.19.549812 — molecular biology — Posted on 2023-07-20
1504 Characterization of the Plasmodium berghei regulatory AAA-ATPase subunit Rpt3 as an activator of Protein Phosphatase 1: direct and indirect evidence
Laine, C.; De Witte, C.; Martoriati, A.; Farce, A.; Metatla, I.; Guerrera, I. C.; Cailliau, K.; Khalife, J.; Pierrot, C.
10.1101/2023.07.20.549862 — microbiology — Posted on 2023-07-20
1505 MERTK Coordinates Efferocytosis by Regulating Integrin Localization and Activation
Dickson, B. H.; Tassnim, T.; Lam, A. L.; Vreize, A.; Blythe, E. N.; Dekaban, G. A.; Heit, B.
10.1101/2023.07.20.549870 — immunology — Posted on 2023-07-20
1507 Probing the physiological role of the plastid outer-envelope membrane using the oemiR plasmid collection
Schwenkert, S.; Lo, W. T.; Szulc, B.; Yip, C. K.; Pratt, A. I.; Cusack, S. A.; Brandt, B.; Leister, D.; Kunz, H.-H.
10.1101/2023.07.20.549935 — plant biology — Posted on 2023-07-20
1509 The hGID GID4 E3 ubiquitin ligase complex targets ARHGAP11A to regulate cell migration
Bagci, H.; Winkler, M.; Uliana, F.; Boulais, J.; Mohamed, W. I.; Park, S. L.; Cote, J.-F.; Peter, M.
10.1101/2023.07.20.549906 — biochemistry — Posted on 2023-07-20
1511 σ28-dependent small RNA regulation of flagella biosynthesis
Melamed, S.; Zhang, A.; Jarnik, M.; Mills, J.; Silverman, A.; Zhang, H.; Storz, G.
10.1101/2021.08.05.455139 — microbiology — Posted on 2023-07-20
1512 A tripartite bacterial-fungal-plant symbiosis in the mycorrhiza-shaped microbiome drives plant growth and mycorrhization
Zhang, C.; van der Heijden, M. G. A.; Dodds, B. K.; Nguyen, T. B.; Spooren, J.; Held, A.; Cosme, M.; Berendsen, R.
10.1101/2023.07.19.549792 — microbiology — Posted on 2023-07-20
1513 Complete Protection from SARS-CoV-2 Lung Infection in Mice Through Combined Intranasal Delivery of PIKfyve Kinase and TMPRSS2 Protease Inhibitors
Kant, R.; Kareinen, L.; Ojha, R.; Strandin, T.; Saber, S. H.; Lesnikova, A.; Kuivanen, S.; Sironen, T.; Joensuu, M.; Vapalahti, O.; Kirchhausen, T.; Kipar, A.; Balistreri, G.
10.1101/2023.07.19.549731 — microbiology — Posted on 2023-07-20
1514 Enterocloster clostridioformis induces host intestinal epithelial responses that protect against Salmonella infection
Beresford-Jones, B. S.; Suyama, S.; Clare, S. A.; Soderholm, A. T.; Xia, W.; Sardar, P.; Harcourt, K.; Lawley, T. D.; Pedicord, V. A.
10.1101/2023.07.20.549886 — microbiology — Posted on 2023-07-20
1515 No evidence for the association between COVID-19 and neuroinflammation: A diffusion basis spectrum imaging study.
Zhang, W.; Gorelik, A. J.; Wang, Q.; Norton, S. A.; Hershey, T.; Bijsterbosch, J. D.; Bogdan, R.
10.1101/2023.07.20.549891 — neuroscience — Posted on 2023-07-20
1522 Characterization of the RBM15 protein binding with XCI-escaping long noncoding RNAs
Jones, A.; Mayes, C.; Bose, E.; Ellis, L.; Baker, C.; Tambalotti, S.; Xiong, S.; Sarpong, Y. P. O.; Shalaby, M.; Barry, L.; Lewis, F.; Joseph, J.; Isaacs, T.; McCarthy, D.; Katz, D.; Wang, J.; Zirimu, V.; Vargas, L.; Von Hofe, J.; Aguilar, G.; Buchan, K.; Zheng, L.; Wolfe, G.
10.1101/2023.07.20.549950 — biochemistry — Posted on 2023-07-20
1524 Cytosolic linear DNA plasmids in Saccharomycopsis species
O Cinneide, E.; Heneghan, P. G.; Rajkumar, A.; Morrissey, J.; Wolfe, K. H.
10.1101/2023.07.20.549855 — evolutionary biology — Posted on 2023-07-20
1525 Social and environmental transmission spread different sets of gut microbes in wild mice
Raulo, A. M.; Buerkner, P.; Dale, J.; English, H. M.; Finerty, G.; Lamberth, C.; Firth, J.; Coulson, T.; Knowles, S. C.
10.1101/2023.07.20.549849 — ecology — Posted on 2023-07-20
1526 Loss of REP1 impacts choroidal melanogenesis in choroideremia
Sarkar, H.; Tracey-White, D.; Hagag, A. M.; Burgoyne, T.; Jensen, L. D.; Edwards, M.; Moosajee, M.
10.1101/2023.07.20.549875 — molecular biology — Posted on 2023-07-20
1531 Design of SARS-CoV-2 protease inhibitors with improved affinity and reduced sensitivity to mutations
Westberg, M.; Su, Y.; Zou, X.; Huang, P.; Rustagi, A.; Garhyan, J.; Patel, P. B.; Fernandez, D.; Wu, Y.; Ning, L.; Beck, A.; Karim, M.; Hao, C.; Saenkham-Huntsinger, P.; Tat, V.; Drelich, A.; Peng, B.-H.; Einav, S.; Tseng, C.-T. K.; Blish, C.; Lin, M. Z.
10.1101/2023.07.19.549739 — microbiology — Posted on 2023-07-20
1534 Microbial Respiration in Contrasting Ocean Provinces via High-Frequency Optical Assays
Cohn, M. R.; Stephens, B.; Meyer, M. G.; Sharpe, G. C.; Niebergall, A. K.; Graff, J. R.; Cassar, N.; Marchetti, A.; Carlson, C. A.; Gifford, S. M.
10.1101/2023.07.20.549894 — microbiology — Posted on 2023-07-20
1536 A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data
Zuffa, S.; Schmid, R.; Bauermeister, A.; P. Gomes, P. W.; Caraballo-Rodriguez, A. M.; El Abiead, Y.; Aron, A. T.; Gentry, E. C.; Zemlin, J.; Meehan, M. J.; Avalon, N. E.; Cichewicz, R. H.; Buzun, E.; Carrillo Terrazas, M.; Hsu, C.-Y.; Oles, R.; Vasquez Ayala, A.; Zhao, J.; Chu, H.; Kuijpers, M. C. M.; Jackrel, S. L.; Tugizimana, F.; Nephali, L. P.; Dubery, I. A.; Madala, N. E.; Moreira, E. A.; Costa-Lotufo, L. V.; Lopes, N. P.; Rezende-Teixeira, P.; Jimenez, P. C.; Rimal, B.; Patterson, A. D.; Traxler, M. F.; Pessotti, R. d. C.; Alvarado-Villalobos, D.; Tamayo-Castillo, G.; Chaverri, P.; Escud
10.1101/2023.07.20.549584 — microbiology — Posted on 2023-07-20
1540 Dynamics of cortical contrast adaptation predict perception of signals in noise.
Angeloni, C. F.; Mlynarski, W.; Piasini, E.; Williams, A. M.; Wood, K. C.; Garami, L.; Hermundstad, A.; Geffen, M. N.
10.1101/2021.08.11.455845 — neuroscience — Posted on 2023-07-20
1543 NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis
Castel, J.; Li, G.; Onimus, O.; Leishman, E.; Cani, P. D.; Bradshaw, H. B.; Mackie, K.; Everard, A.; Luquet, S.; Gangarossa, G.
10.1101/2023.07.19.549235 — neuroscience — Posted on 2023-07-20
1546 Mu-opioid receptor-dependent changes in social reward across adolescence in mice
Harda, Z.; Klimczak, M.; Misiolek, K.; Chroszcz, M.; Szumiec, L.; Jarosz, M. K.; Rygula, R.; Ziolkowska, B.; Parkitna, J. R.
10.1101/2023.07.19.549691 — neuroscience — Posted on 2023-07-20
1547 NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis
Castel, J.; Li, G.; Onimus, O.; Leishman, E.; Cani, P. D.; Bradshaw, H. B.; Mackie, K.; Everard, A.; Luquet, S.; Gangarossa, G.
10.1101/2023.07.19.549235 — neuroscience — Posted on 2023-07-20
1550 Differential expression of miRNAs between Young-Onset and Late-Onset Indian colorectal carcinoma patients
Moiz, S.; Mondal, V.; Bishnu, D.; Das, B.; Bose, B.; Das, S.; Banerjee, N.; Dutta, A.; Chatterjee, K.; Goswami, S.; Mukhopadhyay, S.; Basu, S.
10.1101/2023.07.19.549649 — cancer biology — Posted on 2023-07-20
1551 Unified fate mapping in multiview single-cell data
Weiler, P.; Lange, M.; Klein, M.; Pe'er, D.; Theis, F.
10.1101/2023.07.19.549685 — bioinformatics — Posted on 2023-07-20
1553 Calcium-permeable AMPA receptors govern PV neuron feature selectivity
Hong, I.; Kim, J.; Hainmueller, T.; Kim, D. W.; Johnson, R. C.; Park, S. H.; Limjunyawong, N.; Yang, Z.; Cheon, D.; Hwang, T.; Agarwal, A.; Cholvin, T.; Krienen, F. M.; McCarroll, S. A.; Dong, X.; Leopold, D. A.; Blackshaw, S.; Bergles, D. E.; Bartos, M.; Brown, S. P.; Huganir, R. L.
10.1101/2023.07.20.549908 — neuroscience — Posted on 2023-07-20
1556 ERK signalling orchestrates metachronous transition from naive to formative pluripotency
Mulas, C.; Stammers, M.; Salomaa, S. I.; Heinzen, C.; Suter, D. M.; Smith, A.; Chalut, K. J.
10.1101/2023.07.20.549835 — developmental biology — Posted on 2023-07-20
1557 Pancreatic islet cell stress induced by insulin-degrading enzyme deficiency promotes islet regeneration and protection from autoimmune diabetes
Zhu, S.; Waeckel-Enee, E.; Moser, A.; Bessard, M.-A.; Roger, K.; Lipecka, J.; Yilmaz, A.; Bertocci, B.; Diana, J.; Saintpierre, B.; Guerrera, I. C.; Francesconi, S.; Mauvais, F.-X.; van Endert, P.
10.1101/2023.07.19.549693 — cell biology — Posted on 2023-07-20
1558 Continuous endosomes form functional subdomains and orchestrate rapid membrane trafficking in trypanosomes
Link, F.; Borges, A.; Karo, O.; Jungblut, M.; Mueller, T.; Meyer-Natus, E.; Krueger, T.; Sachs, S.; Jones, N. G.; Morphew, M.; Sauer, M.; Stigloher, C.; McIntosh, J. R.; Engstler, M.
10.1101/2023.07.20.549860 — cell biology — Posted on 2023-07-20
1559 Post-translational regulation of the Numb/Notch pathway in neurogenesis and cancer by Dlk2
Telerman, S. B.; Hamilton, R. S.; Shaw, B.; Dimitrov, J. D.; Steventon, B.; Ferguson-Smith, A. C.
10.1101/2023.07.20.549453 — cell biology — Posted on 2023-07-20
1561 AMPK targets PDZD8 to trigger carbon source shift to glutamine
Li, M.; Wang, Y.; Wei, X.; Cai, W.-F.; Zhu, M.; Yao, L.; Wang, Y.; Liu, Y.-H.; Wu, J.; Xiong, J.; Tian, X.; Qu, Q.; Xie, R.; Li, X.; Chen, S.; Huang, X.; Zhang, C.; Xie, C.; Wu, Y.; Xu, Z.; Zhang, B.; Jiang, B.; Yu, Y.; Wang, Z.-C.; Li, Q.; Li, G.; Lin, S.-Y.; Yu, L.; Piao, H.-l.; Deng, X.; Zhang, C.-S.; Lin, S.-C.
10.1101/2023.07.20.548338 — cell biology — Posted on 2023-07-20
1562 A molecular toolbox to study progesterone receptor signaling
Aarts, M. T.; Wagner, M.; van der Wal, T.; van Boxtel, A. L.; van Amerongen, R.
10.1101/2023.07.20.549847 — cell biology — Posted on 2023-07-20
1563 Spatiotemporal precise optical manipulation of intracellular molecular activities
Dong, B.; Mahapatra, S.; Clark, M. G.; Carlsen, M.; Mohn, K. J.; Ma, S.; Brasseale, K.; Crim, G.; Zhang, C.
10.1101/2023.07.19.549752 — cell biology — Posted on 2023-07-20
1566 Megakaryocyte infection by SARS-CoV-2 drives the formation of pathogenic afucosylated IgG antibodies in mice
Mabrouk, M.; Jalali, F.; Zaid, N.; Naya, A.; Khyatti, M.; Khalki, L.; Guessous, F.; Zaid, Y.
10.1101/2023.07.14.549113 — immunology — Posted on 2023-07-20
1569 Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease
Zhang, K.; Eldin, P.; Ciesla, J. H.; Briant, L.; Lentini, J. M.; Ramos, J.; Cobb, J.; Munger, J.; Fu, D.
10.1101/2023.02.10.527147 — molecular biology — Posted on 2023-07-20
1570 Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
Yisimayi, A.; Song, W.; Wang, J.; Jian, F.; Yu, Y.; Chen, X.; Xu, Y.; Yang, S.; Niu, X.; Xiao, T.; Wang, J.; Zhao, L.; Sun, H.; An, R.; Zhang, N.; Wang, Y.; Wang, P.; Yu, L.; Lv, Z.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Wang, Y.; Xie, X. S.; Cao, Y.
10.1101/2023.05.01.538516 — immunology — Posted on 2023-07-20
1571 Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity decoder
Sanchez-Rodriguez, L. M.; Bezgin, G.; Carbonell, F.; Therriault, J.; Fernandez-Arias, J.; Servaes, S.; Rahmouni, N.; Tissot, C.; Stevenson, J.; Karikari, T. K. M.; Ashton, N. J.; Benedet, A.; Zetterberg, H.; Blennow, K.; Triana-Baltzer, G.; Kolb, H. C.; Rosa-Neto, P.; Iturria-Medina, Y.
10.1101/2023.02.21.529377 — neuroscience — Posted on 2023-07-20
1573 Evaluation of surface-based hippocampal registration using ground-truth subfield definitions
DeKraker, J.; Palomero-Gallagher, N.; Kedo, O.; Ladbon-Bernasconi, N.; Muenzing, S. E. A.; Axer, M.; Amunts, K.; Khan, A. R.; Bernhardt, B.; Evans, A. C.
10.1101/2023.03.30.534978 — neuroscience — Posted on 2023-07-20
1575 Thalamus drives active dendritic computations in cortex
Bast, A.; Guest, J. M.; Fruengel, R.; Narayanan, R. T.; de Kock, C. P. J.; Oberlaender, M.
10.1101/2021.10.21.465325 — neuroscience — Posted on 2023-07-20
1576 Cortical-brainstem circuitry attenuates stress reactivity
Pace, S.; Lukinic, E.; Wallace, T.; McCartney, C.; Myers, B.
10.1101/2023.07.19.549781 — neuroscience — Posted on 2023-07-20
1578 CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis
Haldar, A. N.; Oza, V. H.; DeVoss, N. S.; Clark, A. D.; Lasseigne, B. N.
10.1101/2023.04.21.537877 — bioinformatics — Posted on 2023-07-20
1579 Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing
Yin, J.-A.; Frick, L.; Scheidmann, M. C.; Liu, T.; Trevisan, C.; Dhingra, A.; Spinelli, A.; Wu, Y.; Yao, L.; Vena, D. L.; Knapp, B.; De Cecco, E.; Ging, K.; Armani, A.; Oakeley, E.; Nigsch, F.; Jenzer, J.; Haegele, J.; Pikusa, M.; Tager, J.; Rodriguez-Nieto, S.; Guo, J.; Bouris, V.; Ribeiro, R.; Baroni, F.; Bedi, M. S.; Berry, S.; Losa, M.; Hornemann, S.; Kampmann, M.; Pelkmans, L.; Hoepfner, D.; Heutink, P.; Aguzzi, A.
10.1101/2022.05.25.493370 — genomics — Posted on 2023-07-20
1588 Mechanosensing and Sphingolipid-Docking Mediate Lipopetide-Induced Immunity in Arabidopsis
Prsic, J.; Gilliard, G.; Ibrahim, H.; Arguelles Arias, A.; Rondelli, V.; Crowet, J.-M.; Genva, M.; Luzuriaga Loaiza, W. P.; Deboever, E.; Nasir, N.; Lins, L.; Mathelie-Guinlet, M.; Eschrig, S.; Ranf, S.; Dorey, S.; De Coninck, B.; Nurnberger, T.; Mongrand, S.; Hofte, M.; Zipfel, C.; Dufrene, Y.; Koutsioubas, A.; Brocca, P.; Deleu, M.; Ongena, M.
10.1101/2023.07.04.547613 — plant biology — Posted on 2023-07-20
1589 The International Weed Genomics Consortium: Community Resources for Weed Genomics Research
Montgomery, J. S.; Morran, S.; MacGregor, D. R.; McElroy, J. S.; Neve, P.; Neto, C.; Vila-Aiub, M. M.; Sandoval, M. V.; Menendez, A. I.; Kreiner, J.; Fan, L.; Caicedo, A. L.; Maughan, P. J.; Martins, B. A. B.; Mika, J.; Collavo, A.; Merotto, A.; Subramanian, N. K.; Bagavathiannan, M. V.; Cutti, L.; Islam, M. M.; Gill, B. S.; Cicchillo, R.; Gast, R.; Soni, N.; Wright, T. R.; Zastrow-Hayes, G.; May, G.; Malone, J. M.; Sehgal, D.; Kaundun, S. S.; Dale, R. P.; Vorster, B. J.; Peters, B.; Lerchl, J.; Tranel, P. J.; Beffa, R.; Jugulam, M.; Fengler, K.; Llaca, V.; Patterson, E. L.; Gaines, T. A.
10.1101/2023.07.19.549613 — genomics — Posted on 2023-07-20
1590 Switch-Like Phosphorylation of WRN Integrates End-Resection with RAD51 Metabolism at Collapsed Replication Forks
Palermo, V.; Malacaria, E.; Semproni, M.; Sanchez, M.; Marini, F.; Pellicioli, A.; Franchitto, A.; Pichierri, P.
10.1101/403808 — cell biology — Posted on 2023-07-20
1591 RNA polymerase III is involved in regulating Plasmodium falciparum virulence
Diffendall, G. M.; Claes, A.; Barcons-Simon, A.; Nyarko, P.; Dingli, F.; Loew, D.; Claessens, A.; Scherf, A.
10.1101/2023.07.18.549525 — microbiology — Posted on 2023-07-20
1592 TcZC3HTTP, a regulatory element that contributes to Trypanosoma cruzi cell proliferation
Romagnoli, B. A. A.; Freire, E.; Castro, A. R. L.; Munhoz da Rocha, I. F.; Alves, L. R.; Goldenberg, S.
10.1101/2023.07.17.549355 — microbiology — Posted on 2023-07-20
1593 RIF1 acts as a gatekeeper of B cell identity during late differentiation
Rahjouei, A.; Kabrani, E.; Berruezo-Llacuna, M.; Altwasser, R.; Delgado-Benito, V.; Pavri, R.; Di Virgilio, M.
10.1101/2023.07.18.549543 — immunology — Posted on 2023-07-20
1599 De novo progesterone synthesis in plants
Li, R.; Guo, S.; Wang, D.; Yang, T.; Zhang, X.; Dai, Z.
10.1101/2023.07.19.549634 — plant biology — Posted on 2023-07-20
1600 On-Demand Expansion Fluorescence and Photoacoustic Microscopy (ExFLPAM)
Mu, X.; Ma, C.; Mei, X.; Liao, J.; Bojar, R.; Kuang, S.; Rong, Q.; Yao, J.; Zhang, Y. S.
10.1101/2023.07.19.549787 — bioengineering — Posted on 2023-07-20
1601 Using dynamic biomaterials to study the temporal role of osteogenic growth peptide during osteogenesis
Fumasi, F. M.; MacCulloch, T.; Bernal-Chanchavac, J.; Stephanopoulos, N.; Holloway, J. L.
10.1101/2023.07.19.549767 — bioengineering — Posted on 2023-07-20
1602 Genome editing induces the transfer of mitochondrial DNA into the nuclear genome
Wu, J.; Liu, Y.; Ou, L.; Gan, T.; Zhangding, Z.; Yuan, S.; Liu, M.; Liu, X.; Li, J.; Yin, J.; Xin, C.; Tian, Y.; Hu, J.
10.1101/2023.07.19.549443 — genomics — Posted on 2023-07-20
1603 The Genomic Legacy of Human Management and sex-biased Aurochs hybridization in Iberian Cattle
Günther, T.; Chisausky, J.; Galindo-Pellicena, M. A.; Iriarte, E.; Cortes Gardyn, O.; Eusebi, P. G.; Garcia-Gonzalez, R.; Urena, I.; Moreno, M.; Alday, A.; Rojo, M.; Perez, A.; Tejedor Rodriguez, C.; Garcia Martinez de Lagran, I.; Arsuaga, J. L.; Carretero, J.-M.; Götherström, A.; Smith, C.; Valdiosera, C.
10.1101/2023.07.19.548914 — genomics — Posted on 2023-07-20
1605 Establishment and maintenance of two sand fly colonies (Phlebotomus perniciosus and Phlebotomus papatasi) to implement experimental infections
Prudhomme, J.; Laroche, L.; Nguyen Hoang Quan, A.; Fournier, J.; Mhaidi, I.; Berhard, A.; Killick-Kendrick, M.; Banuls, A.-L.
10.1101/2023.07.19.549665 — ecology — Posted on 2023-07-20
1606 Coupling remote sensing and eDNA to monitor environmental impact: A pilot to quantify the environmental benefits of sustainable agriculture in the Brazilian Amazon
Dyson, K.; Nicolau, A. P.; Tenneson, K.; Francesconi, W.; Daniels, A.; Andrich, G.; Caldas, B.; Castano, S.; de Campos, N.; Dilger, J.; Guidotti, V.; Jaques, I.; McCullough, I. M.; McDevitt, A. D.; Molina, L.; Nekorchuk, D. M.; Newberry, T.; Pereira, C. L.; Perez, J.; Richards-Dimitrie, T.; Rivera, O.; Rodriguez, B.; Sales, N.; Tello, J.; Wespestad, C.; Zutta, B.; Saah, D.
10.1101/2023.07.19.549776 — ecology — Posted on 2023-07-20
1608 Dynein and dynactin move long-range but are delivered separately to the axon tip
Fellows, A. D.; Bruntraeger, M.; Burgold, T.; Bassett, A. R.; Carter, A. P.
10.1101/2023.07.03.547521 — cell biology — Posted on 2023-07-20
1613 Investigating robust associations between functional connectivity based on graph theory and general intelligence
Metzen, D.; Stammen, C.; Fraenz, C.; Schlüter, C.; Johnson, W.; Güntürkün, O.; DeYoung, C. G.; Genc, E.
10.1101/2023.07.18.549314 — neuroscience — Posted on 2023-07-20
1614 Exposure to early life stress impairs weight loss maintenance success in mice.
Foright, R. M.; McQuillan, T. E.; Frick, J. M.; Minchella, P. M.; Levasseur, B. M.; Tinoco, O.; Birmingham, L.; Lewis, A. E.; Thyfault, J. P.; Christianson, J. A.
10.1101/2023.07.19.549724 — physiology — Posted on 2023-07-20
1619 Analysis of Drosophila and mouse mutants reveals that Peroxidasin is required for tissue mechanics and full viability
Peebles, K. E.; LaFever, K. S.; Page-McCaw, P. S.; Colon, S.; Wang, D.; Stricker, A. M.; Ferrell, N.; Bhave, G.; Page-McCaw, A.
10.1101/2023.07.19.549730 — cell biology — Posted on 2023-07-19
1621 Mesostriatal dopamine is sensitive to specific cue-reward contingencies
Garr, E.; Cheng, Y.; Jeong, H.; Brooke, S.; Castell, L.; Bal, A.; Magnard, R.; Namboodiri, V. M. K.; Janak, P. H.
10.1101/2023.06.05.543690 — neuroscience — Posted on 2023-07-19
1623 Essential role of PLD2 in hypoxia-induced stemness and therapy resistance in ovarian tumors
Munoz-Galvan, S.; Verdugo-Sivianes, E. M.; Santos-Pereira, J. M.; Estevez-Garcia, P.; Carnero, A.
10.1101/2023.07.19.549738 — cancer biology — Posted on 2023-07-19
1628 Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice
Ding, Y.; Yanagi, K.; Yang, F.; Callaway, E.; Cheng, C.; Hensel, M.; Menon, R.; Alaniz, R.; Lee, K.; Jayaraman, A.
10.1101/2023.03.21.533660 — cell biology — Posted on 2023-07-19
1629 CircRNAs and their regulatory networks associated with the antioxidant enzymes and immune responses of Asian honey bee larvae to fungal infection
Guo, R.; Zhang, K.; Gao, X.; Jing, X.; Guo, S.; Zang, H.; Song, Y.; Li, K.; Zou, P.; Chen, M.; Wu, Y.; Huang, Z.; Fu, Z.; Chen, D.
10.1101/2023.07.19.549790 — molecular biology — Posted on 2023-07-19
1631 Effort cost of harvest affects decisions and movement vigor of marmosets during foraging
Hage, P.; Jang, I. K.; Looi, V.; Fakharian, M. A.; Orozco, S. P.; Sedaghat-Nejad, E.; Pi, J.; Shadmehr, R.
10.1101/2023.02.04.527146 — neuroscience — Posted on 2023-07-19
1632 Linking Choroid Plexus Enlargement with Plasma Analyte and Structural Phenotypes in Clinical High Risk for Psychosis: A Multisite Neuroimaging Study
Bannai, D.; Reuter, M.; Hegde, R.; Hoang, D.; Adhan, I.; Gandu, S.; Pong, S.; Raymond, N.; Zeng, V.; Chung, Y.; He, G.; Sun, D.; van Erp, T. G. M.; Addington, J.; Bearden, C. E.; Cadenhead, K.; Cornblatt, B.; Mathalon, D. H.; McGlashan, T.; Jeffries, C.; Stone, W.; Tsuang, M.; Walker, E.; Woods, S. W.; Cannon, T. D.; Perkins, D.; Keshavan, M.; Lizano, P.
10.1101/2022.10.28.514160 — neuroscience — Posted on 2023-07-19
1634 Use of Large Language Models to Aid Analysis of Textual Data
Tai, R. H.; Bentley, L. R.; Xia, X.; Sitt, J. M.; Fankhauser, S. C.; Chicas-Mosier, A. M.; Monteith, B. G.
10.1101/2023.07.17.549361 — scientific communication and education — Posted on 2023-07-19
1635 A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2
Rodencal, J.; Kim, N.; Li, V.; He, A.; Lange, M.; He, J.; Tarangelo, A.; Schafer, Z. T.; Olzmann, J.; Sage, J.; Long, J. Z.; Dixon, S. J.
10.1101/2023.07.19.549715 — cancer biology — Posted on 2023-07-19
1636 A semiconductor 96-microplate platform for real-time impedance-based high-throughput screening
Chitale, S.; Wu, W.; Mukherjee, A.; Lannon, H.; Suresh, P.; Nag, I.; Ambrosi, C.; Gertner, R. A.; Melo, H.; Powers, B.; Wilkins, H.; Hinton, H.; Cheah, M.; Boynton, Z.; Alexeyev, A.; Sword, D.; Basan, M.; Park, H.; Ham, D.; Abbott, J.
10.1101/2023.06.01.543281 — bioengineering — Posted on 2023-07-19
1637 Enhanced capillary pumping using open-channel capillary trees with integrated paper pads
Tokihiro, J. C.; Tu, W.-c.; Berthier, J.; Lee, J. J.; Dostie, A. M.; Khor, J. W.; Eakman, M.; Theberge, A. B.; Berthier, E.
10.1101/2022.07.15.500252 — bioengineering — Posted on 2023-07-19
1639 Xrn1 biochemically associates to the eisosome after the post diauxic shift in yeast
Courtin, B.; Namane, A.; Gomard, M.; Meyer, L.; Jacquier, A.; Fromont-Racine, M.
10.1101/2023.07.19.549689 — biochemistry — Posted on 2023-07-19
1640 Spatio-temporal diversity and genetic architecture of pyrantel resistance in Cylicocyclus nassatus, the most abundant horse parasite
Salle, G.; Courtot, E.; Cabau, C.; Parrinello, H.; Serreau, D.; Reigner, F.; Gesbert, A.; Jacquinot, L.; Lenhof, O.; Aime, A.; Picandet, V.; Kuzmina, T.; Holovachov, O.; Bellaw, J.; Nielsen, M. K.; von Samson-Himmelstjerna, G.; Valiere, S.; Gislard, M.; Lluch, J.; Kuchly, C.; Klopp, C.
10.1101/2023.07.19.549683 — genomics — Posted on 2023-07-19
1641 Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth
Johnson, K. E.; Heisel, T.; Fields, D. A.; Isganaitis, E.; Jacobs, K. M.; Knights, D.; Lock, E. F.; Rudolph, M. C.; Gale, C. A.; Schleiss, M. R.; Albert, F. W.; Demerath, E. W.; Blekhman, R.
10.1101/2023.07.19.549370 — genomics — Posted on 2023-07-19
1642 A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation
Fellmeth, J.; Jang, J. K.; Persaud, M.; Sturm, H.; Changela, N.; Parikh, A.; McKim, K. S.
10.1101/2023.03.13.532437 — genetics — Posted on 2023-07-19
1643 Epigenetic Age Acceleration in Surviving versus Deceased COVID-19 Patients with Acute Respiratory Distress Syndrome following Hospitalization
Bejaoui, Y.; Humaira Amanullah, F.; Saad, M.; Taleb, S.; Bradic, M.; Megarbane, A.; Ait Hssain, A.; Abi Khalil, C.; El Hajj, N.
10.1101/2023.07.18.549478 — genetics — Posted on 2023-07-19
1644 CartoCell, a high-content pipeline for accurate 3D image analysis, unveils cell morphology patterns in epithelial cysts.
Andres-San Roman, J. A.; Gordillo-Vazquez, C.; Franco-Barranco, D.; Morato, L.; Fernandez-Espartero, C. H.; Baonza, G.; Tagua, A.; Vicente-Munuera, P.; Palacios, A. M.; Gavilan, M. P.; Martin-Belmonte, F.; Annese, V.; Gomez-Galvez, P.; Arganda-Carreras, I.; Escudero, L. M.
10.1101/2023.01.05.522724 — developmental biology — Posted on 2023-07-19
1645 Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression
Murphy, D.; Salataj, E.; Di Giammartino, D. C.; Rodriguez-Hernaez, J.; Kloetgen, A.; Garg, V.; Char, E.; Uyehara, C. M.; Ee, L.-s.; Lee, U.; Stadtfeld, M.; Hadjantonakis, A.-K.; Tsirigos, A.; Polyzos, A.; Apostolou, E.
10.1101/2023.07.19.549714 — molecular biology — Posted on 2023-07-19
1647 Fitness Tradeoffs of Multidrug Efflux Pumps in Escherichia coli K-12 in Acid or Base, and with Aromatic Phytochemicals
Liu, Y.; Van Horn, A. M.; Pham, M. T. N.; Dinh, B. N. N.; Chen, R.; Raphael, S. D. R.; Paulino, A.; Thaker, K.; Somadder, A.; Menke, C. C.; Slimak, Z. C.; Slonczewski, J. L.
10.1101/2023.07.17.549369 — microbiology — Posted on 2023-07-19
1648 Heterogeneity of foam cell biogenesis across diseases
Guerrini, V.; Prideaux, B.; Khan, R.; Subbian, S.; Wang, Y.; Sadimin, E.; Pawar, S.; Ukey, R.; Singer, E. A.; Xue, C.; Gennaro, M. L.
10.1101/2023.06.08.542766 — immunology — Posted on 2023-07-19
1649 M2-polarized macrophages prevent preterm birth and improve neonatal survival and immunity
Garcia-Flores, V.; Liu, Z.; Romero, R.; Xu, Y.; Miller, D.; Galaz, J.; Winters, A. D.; Farias-Jofre, M.; Theis, K. R.; Gomez-Lopez, N.
10.1101/2023.07.19.549717 — immunology — Posted on 2023-07-19
1653 Spatiotemporal organization of prefrontal norepinephrine influences neuronal activity
Glaeser-Khan, S.; Savalia, N. K.; Cressy, J.; Feng, J.; Li, Y.; Kwan, A. C.; Kaye, A. P.
10.1101/2023.06.09.544191 — neuroscience — Posted on 2023-07-19
1654 SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons
Miyamoto, T.; Kim, C.; Chow, J.; Dugas, J. C.; DeGroot, J.; Bagdasarian, A. L.; Thottumkara, A. P.; Larhammar, M.; Calvert, M. E.; Fox, B. M.; Lewcock, J. W.; Kane, L. A.
10.1101/2022.04.27.489702 — neuroscience — Posted on 2023-07-19
1657 The CRL plastid outer envelope protein supports TOC75-V / OEP80 complex formation in Arabidopsis
Yoshimura, R.; Minamikawa, S.; Suzuki, T.; latrasse, D.; Sicar, S.; Raynaud, C.; Benhamed, M.; Yoshioka, Y.
10.1101/2023.03.07.531578 — plant biology — Posted on 2023-07-19
1658 PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
Yoshida, T.; Latt, K. Z.; Rosenberg, A. Z.; Santo, B. A.; Myakala, K.; Ishimoto, Y.; Zhao, Y.; Shrivastav, S.; Jones, B. A.; Yang, X.; Wang, X.; Tutino, V. M.; Sarder, P.; Levi, M.; Okamoto, K.; Winkler, C. A.; Kopp, J. B.
10.1101/2022.10.03.510678 — pathology — Posted on 2023-07-19
1659 The origin and dynamics of cellular heterogeneity vary across lineage subtypes of castrate resistant prostate cancer
Beshiri, M. L.; Capaldo, B. J.; Lake, R.; Ku, A. T.; Burner, D.; Tice, C. M.; Tran, C.; Kostas, J.; Alilin, A. N.; Yin, J.; Agarwal, S.; Morris, S. A.; Karzai, F. H.; Lotan, T. L.; Dahut, W. L.; Sowalsky, A. G.; Kelly, K.
10.1101/2022.03.24.484651 — cancer biology — Posted on 2023-07-19
1660 High transposase abundance in the deep ocean is linked to a particle-associated lifestyle
Zhong, J.; Kyrysyuk, O.; del Rosario Herhandez, T.; Tully, B. J.; Anderson, R. E.
10.1101/2022.04.27.489810 — bioinformatics — Posted on 2023-07-19
1664 Unifying comprehensive genomics and transcriptomics in individual cells to illuminate oncogenic and drug resistance mechanisms
Marks, J. R.; Zawistowski, J. S.; Salas-Gonzalez, I.; Tate, T. A.; Morozova, T. V.; Blackinton, J. G.; Arvapalli, D. M.; Velivela, S. D.; Harton, G. L.; Gawad, C.; Weigman, V. J.; Hwang, E. S.; West, J. A.
10.1101/2022.04.29.489440 — genomics — Posted on 2023-07-19
1666 A soft tick vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests
Bonsergent, C.; Vittecoq, M.; Leray, C.; Jouglin, M.; Buysse, M.; McCoy, K.; Malandrin, L.
10.1101/2023.03.24.534071 — microbiology — Posted on 2023-07-19
1668 Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie Bandavirus in aged ferrets
Jung, J. U.; Kim, D.; Kim, E.; Kim, S.; Chung, Y.; Cho, S.-D.; Choi, Y.; Lai, C.-J.; Dai, X.; Kang, S.; Kwak, M.-J.; Cha, I.; Liu, Z.; Choi, Y.; Park, S.-H.; Choi, Y. K.; Kim, S.
10.1101/2023.07.19.549761 — microbiology — Posted on 2023-07-19
1669 Genotypic and phenotypic homogeneity of vaginal and rectal yeast isolates from recurrent vulvovaginal candidiasis
Adamu Bukari, A.-R.; Kukurudz, R.; de Graaf, A.; Habon, D.; Manyaz, B.; Syvolos, Y.; Sumanarathnea, A.; Poliquin, V.; Gerstein, A. C.
10.1101/2023.07.19.549743 — microbiology — Posted on 2023-07-19
1672 Activated interstitial macrophages are a predominant target of viral takeover and focus of inflammation in COVID-19 initiation in human lung
Wu, T. T.-H.; Travaglini, K. J.; Rustagi, A.; Xu, D.; Zhang, Y.; Andronov, L.; Jang, S. K.; Gillich, A.; Dehghannasiri, R.; Martinez-Colon, G.; Beck, A.; Liu, D. D.; Wilk, A. J.; Morri, M.; Trope, W. L.; Bierman, R.; Weissman, I. L.; Shrager, J. B.; Quake, S. R.; Kuo, C. S.; Salzman, J.; Moerner, W. E.; Kim, P. S.; Blish, C. A.; Krasnow, M. A.
10.1101/2022.05.10.491266 — genomics — Posted on 2023-07-19
1675 The most remarkable migrants - systematic analysis of the Western European insect flyway at a Pyrenean mountain pass
Hawkes, W. L.; Doyle, T.; Massy, R.; Weston, S.; Davies, K.; Cornelius, E.; Collier, C.; Chapman, J.; Reynolds, D.; Wotton, K.
10.1101/2023.07.17.549321 — zoology — Posted on 2023-07-19
1679 Annual dynamics and distribution of Xylella fastidiosa in infected almond trees
Zecharia, N.; Vanunu, M.; Dror, O.; Hatib, K.; Holland, D.; Shtienberg, D.; Bahar, O.
10.1101/2023.07.17.549336 — plant biology — Posted on 2023-07-19
1680 Wild edible yams from Madagascar: New insights into nutritional composition support their use for food security and conservation
Ratsimbazafy, M. K.; Sharp, P. A.; Razanamparany, L.; Rajaonah, M. T.; Rakotoarison, F.; Khoja, K.; Wilkin, P.; Howes, M.-J. R.
10.1101/2023.07.19.549652 — plant biology — Posted on 2023-07-19
1681 Dopamine-dependent cerebellar dysfunction enhances beta oscillations and disrupts motor learning in a multiarea model
Gambosi, B.; Sheiban, F. J.; Biasizzo, M.; Antonietti, A.; D'Angelo, E. U.; Mazzoni, A.; Pedrocchi, A.
10.1101/2023.07.18.549459 — neuroscience — Posted on 2023-07-19
1683 Identification of Lactuca sativa transcription factors impacting resistance to Botrytis cinerea through predictive network inference
Pink, H.; Talbot, A.; Carter, R.; Hickman, R.; Cooper, O.; Law, R.; Higgins, G.; Yao, C.; Gawthrop, F.; Hand, P.; Pink, D.; Clarkson, J.; Denby, K.
10.1101/2023.07.19.549542 — plant biology — Posted on 2023-07-19
1685 Dimension reduction of microbiome data linked Bifidobacterium to allergic rhinitis
Komaki, S.; Sahoyama, Y.; Hachiya, T.; Koseki, K.; Ogata, Y.; Hamazato, F.; Shiozawa, M.; Nakagawa, T.; Suda, W.; Hattori, M.; Kawakami, E.
10.1101/2023.07.18.548236 — microbiology — Posted on 2023-07-19
1689 Conjugation of cis-OPDA with amino acids is a conserved pathway affecting cis-OPDA homeostasis upon stress responses
Brunoni, F.; Siroka, J.; Mik, V.; Pospisil, T.; Kralova, M.; Ament, A.; Pernisova, M.; Karady, M.; Htitich, M.; Ueda, M.; Flokova, K.; Wasternack, C.; Strnad, M.; Novak, O.
10.1101/2023.07.18.549545 — plant biology — Posted on 2023-07-19
1692 Beyond the MEP Pathway: a novel kinase required for prenol utilization by malaria parasites
Katzin, A. M.; Crispim, M.; Verdaguer, I. B.; Hernandez, A.; Kronenberger, T.; Fenollar, A.; Alberione, M. P.; Ramirez, M.; Izquierdo, L.
10.1101/2023.07.17.549440 — biochemistry — Posted on 2023-07-19
1696 The super-pangenome of Populus unveil genomic facets for adaptation and diversification in widespread forest trees
Shi, T.; Zhang, X.; Hou, Y.; Jiang, Y.; Jia, C.; Lai, Q.; Dan, X.; Feng, J.; Feng, J.; Ma, T.; Wu, J.; Liu, S.; Zhang, L.; Long, Z.; Zhang, Y.; Zhang, J.; Chen, L.; R. Street, N.; K. Ingvarsson, P.; Liu, J.; Yin, T.; Wang, J.
10.1101/2023.07.18.549473 — evolutionary biology — Posted on 2023-07-19
1697 A modular chemigenetic calcium indicator enables in vivo functional imaging with near-infrared light
Farrants, H.; Shuai, Y.; Lemon, W. C.; Hernandez, C. M.; Yang, S.; Patel, R.; Qiao, G.; Frei, M. S.; Grimm, J. B.; Hanson, T. L.; Tomaska, F.; Turner, G. C.; Stringer, C.; Keller, P. J.; Beyene, A. G.; Chen, Y.; Liang, Y.; Lavis, L. D.; Schreiter, E. R.
10.1101/2023.07.18.549527 — neuroscience — Posted on 2023-07-19
1698 The impact of late Pleistocene mammal extinctions on pathogen richness in extant hosts.
Prys-Jones, T. O.; Abraham, A. J.; Mihaljevic, J. R.; Murray, K. A.; Doughty, C. E.
10.1101/2023.07.18.549351 — paleontology — Posted on 2023-07-19
1699 Effect of sample preprocessing and extraction methods on the physical and molecular profiles of extracellular vesicles
Alexandre, L.; Shen, M. L.; Fernandes de Araujo, L. O.; Renault, J.; DeCorwin-Martin, P.; Martel, R.; Ng, A.; Juncker, D.
10.1101/2023.07.17.549204 — bioengineering — Posted on 2023-07-19
1704 Spinal neural tube formation and regression in human embryos
Santos, C.; Murray, A.; Marshall, A. R.; Metcalfe, K.; Narayan, P.; de Castro, S. C. P.; Maniou, E.; Greene, N. D. E.; Galea, G. L.; Copp, A. J.
10.1101/2023.07.18.549464 — developmental biology — Posted on 2023-07-19
1707 Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions
Yu, C.; Lad, E. M.; Mathew, R.; Littleton, S.; Chen, Y.; Schlepckow, K.; Degan, S.; Chew, L.; Amason, J.; Kalnitsky, J.; Bowes Rickman, C.; Proia, A. D.; Colonna, M.; Haass, C.; Saban, D.
10.1101/2023.07.19.549403 — immunology — Posted on 2023-07-19
1709 RIF1 acts as a gatekeeper of B cell identity during late differentiation
Rahjouei, A.; Kabrani, E.; Berruezo-Llacuna, M.; Altwasser, R.; Delgado-Benito, V.; Pavri, R.; Di Virgilio, M.
10.1101/2023.07.18.549543 — immunology — Posted on 2023-07-19
1710 A spatial threshold for astrocyte calcium surge
Lines, J.; Baraibar, A. M.; Nanclares, C.; Martin, E.; Aguilar, J. d. l. R.; Kofuji, P.; Navarrete, M.; Araque, A.
10.1101/2023.07.18.549563 — neuroscience — Posted on 2023-07-19
1713 Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components using a large adolescent sample
Smith, D. M.; Parekh, P.; Kennedy, J.; Loughnan, R. J.; Frei, O.; Nichols, T. E.; Andreassen, O. A.; Jernigan, T. L.; Dale, A. M.
10.1101/2023.07.17.549390 — neuroscience — Posted on 2023-07-19
1714 Spatial Dynamic Subspaces Encode Sex-Specific Schizophrenia Disruptions in Transient Network Overlap and its Links to Genetic Risk
Iraji, A.; Chen, J.; Lewis, N.; Fu, Z.; Agcaoglu, O.; Kochunov, P.; Adhikari, B. M.; Mathalon, D. H.; Pearlson, G. D.; Macciardi, F.; Preda, A.; van Erp, T. G. M.; Bustillo, J. R.; Diaz-Caneja, C. M.; Andres-Camazon, P.; Dhamala, M.; Adali, T.; Calhoun, V. D.
10.1101/2023.07.18.548880 — neuroscience — Posted on 2023-07-19
1717 Registered report: Age-preserved semantic memory and the CRUNCH effect manifested as differential semantic control networks: an fMRI study
Haitas, N.; Dubuc, J.; Masse-Leblanc, C.; Chamberland, V.; Amiri, M.; Glatard, T.; Wilson, M.; Joanette, Y.; Steffener, J.
10.1101/2023.07.19.549657 — neuroscience — Posted on 2023-07-19
1718 Development of a mobile, high-throughput, and low-cost image-based plant growth phenotyping system
Yu, L.; Sussman, H.; Khmelnitsky, O.; Ishka, M. R.; Srinivasan, A.; Nelson, A.; Julkowska, M. M.
10.1101/2023.07.18.549560 — plant biology — Posted on 2023-07-19
1719 Methanolic extracts of the edible halophyte Crithmum maritimum enhance oxidative stress resistance in Caenorhabditis elegans through hormetic mechanisms
MARTINS NOGUEROL, R.; Mata Cabana, A.; Olmedo, M.; DeAndres-Gil, C.; MOREIRA, X.; Francisco, M.; Moreno Perez, A. J.; CAMBROLLE, J.
10.1101/2023.07.19.549636 — pharmacology and toxicology — Posted on 2023-07-19
1720 Coordinated inheritance of extrachromosomal DNA species in human cancer cells
Hung, K. L.; Jones, M. G.; Wong, I. T.-L.; Lange, J. T.; Luebeck, J.; Scanu, E.; He, B. J.; Brückner, L.; Li, R.; Gonzalez, R. C.; Schmargon, R.; Dörr, J. R.; Belk, J. A.; Bafna, V.; Werner, B.; Huang, W.; Henssen, A. G.; Mischel, P. S.; Chang, H. Y.
10.1101/2023.07.18.549597 — cancer biology — Posted on 2023-07-19
1721 Quantum effects on histone deacetylation and cellular transcription
Yasuda, T.; Ogi, T.; Nakajima, N.; Yanaka, T.; Tanaka, I.; Tajima, K.
10.1101/2023.07.18.549607 — biophysics — Posted on 2023-07-19
1722 Phase-Separated Droplets Swim to Their Dissolution
Jambon-Puillet, E.; Testa, A.; Lorenz, C. M.; Style, R. W.; Rebane, A.; Dufresne, E. R.
10.1101/2023.07.18.549556 — biophysics — Posted on 2023-07-19
1725 Estimating error rates for single molecule protein sequencing experiments
Smith, M. B.; VanderVelden, K.; Blom, T.; Stout, H. D.; Mapes, J. H.; Folsom, T. M.; Martin, C.; Bardo, A. M.; Marcotte, E. M.
10.1101/2023.07.18.549591 — bioinformatics — Posted on 2023-07-19
1730 ACKR3-arrestin2/3 complexes reveal molecular consequences of GRK-dependent barcoding
Chen, Q.; Schafer, C. T.; Mukherjee, S.; Gustavsson, M.; Agrawal, P.; Yao, X.-Q.; Kossiakoff, A. A.; Handel, T.; Tesmer, J. J. G.
10.1101/2023.07.18.549504 — biochemistry — Posted on 2023-07-19
1731 A nearly complete and phased genome assembly of a Colombian Trypanosoma cruzi TcI strain and the evolution of gene families
Hoyos Sanchez, M. C.; Ospina Zapata, H. S.; Suarez, B. D.; Ospina, C.; Barbosa, H. J.; Carranza Martinez, J. C.; Vallejo, G. A.; Urrea Montes, D.; Duitama, J.
10.1101/2023.07.17.549441 — genomics — Posted on 2023-07-19
1733 A Refined Phylochronology of the Second Plague Pandemic in Western Eurasia
Keller, M.; Guellil, M.; Slavin, P.; Saag, L.; Irdt, K.; Niinemae, H.; Solnik, A.; Malve, M.; Valk, H.; Kriiska, A.; Cessford, C.; Inskip, S. A.; Robb, J. E.; Cooper, C.; von Planta, C.; Seifert, M.; Reitmaier, T.; Baetsen, W. A.; Walker, D.; Loesch, S.; Szidat, S.; Metspalu, M.; Kivisild, T.; Tambets, K.; Scheib, C. L.
10.1101/2023.07.18.549544 — genomics — Posted on 2023-07-19
1738 Population genomics and epigenomics provide insights into the evolution of facultative asexuality in plants
Wang, Y.; Duchen, P.; Chavez, A.; Sree, K. S.; Appenroth, K. J.; Zhao, H.; Widmer, A.; Huber, M.; Xu, S.
10.1101/2023.07.18.549461 — evolutionary biology — Posted on 2023-07-19
1741 The miR-144/Hmgn2 regulatory axis orchestrates chromatin organization during erythropoiesis
Kretov, D.; Folkes, L.; Mora-Martin, A.; Syedah, N.; Walawalkar, I. A.; Vanuytsel, K.; Murphy, G. J.; Moxon, S.; Cifuentes, D.
10.1101/2023.07.18.549576 — developmental biology — Posted on 2023-07-19
1742 Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level
Dorgau, B.; Collin, J.; Rozanska, A.; Boczonadi, V.; MoyaMolina, M.; Hussain, R.; Coxhead, J.; Dhanaseelan, T.; Armstrong, L.; Queen, R.; Lako, M.
10.1101/2023.07.19.549507 — developmental biology — Posted on 2023-07-19
1743 Loss of the mitochondrial citrate carrier, SLC25A1/CIC disrupts embryogenesis via 2-Hydroxyglutarate
Kasprzyk-Pawelec, A.; Tan, M.; Phua, Y.-L.; Rahhal, R.; McIntosh, A.; Fernandez, H.; Mosaoa, R.; Cheema, A.; Jiang, L.; Popratiloff, A.; Clarkson, C.; Pearson, G. W.; Glasgow, E.; Albanese, C.; Vockley, J.; Avantaggiati, M. L.
10.1101/2023.07.18.549409 — developmental biology — Posted on 2023-07-19
1747 A streamlined method to obtain biologically active TcdA and TcdB toxins from Clostridioides difficile
Sapa, A. A. D.; Brosse, A.; Coullon, H.; Pean de Ponfilly, G.; Candela, T.; Le Monnier, A.
10.1101/2023.07.19.549664 — microbiology — Posted on 2023-07-19
1748 An mRNA-encoded, long-lasting Interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
Beck, J. D.; Diken, M.; Suchan, M.; Streuber, M.; Diken, E.; Kolb, L.; Vascotto, F.; Peters, D.; Beissert, T.; Tuereci, O.; Kreiter, S.; Vormehr, M.; Sahin, U.
10.1101/2023.07.18.549445 — immunology — Posted on 2023-07-19
1749 Discovery of post-translationally modified self-peptides that promote hypertension
Bloodworth, N.; Chen, W.; Patrick, D.; Palubinsky, A.; Phillips, E.; Roeth, D.; Kalkum, M.; Mallal, S.; Davies, S. S.; Ao, M.; Moretti, R.; Meiler, J.; Harrison, D. G.
10.1101/2023.07.18.549523 — immunology — Posted on 2023-07-19
1750 IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota
Roewekamp, I.; Maschirow, L.; Rabes, A.; Fiocca Vernengo, F.; Heinz, G. A.; Mashreghi, M.-F.; Caesar, S.; Milek, M.; Fagundes, A.; Wienhold, S.-M.; Nouailles, G.; Yao, L.; Bruder, D.; Boehme, J.; Puzianowska-Kuznicka, M.; Beule, D.; Witzenrath, M.; CAPNETZ Study Group, ; Loehning, M.; Heimesaat, M.; Klose, C. S. N.; Diefenbach, A.; Opitz, B.
10.1101/2023.07.19.549679 — immunology — Posted on 2023-07-19
1752 Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C HIV-1 Vaccine in Rhesus Macaques
Verma, A.; Hawes, C. E.; Elizaldi, S. R.; Smith, J. C.; Rajasundaram, D.; Pedersen, G. K.; Shen, X.; Williams, L. D.; Tomaras, G. D.; Kozlowski, P. A.; Amara, R. R.; Iyer, S. S.
10.1101/2023.07.18.549515 — immunology — Posted on 2023-07-19
1753 Exploratory rearing is governed by hypothalamic MCH cells according to the locus coeruleus
Concetti, C.; Viskaitis, P.; Grujic, N.; Duss, S.; Privitera, M.; Bohacek, J.; Peleg-Raibstein, D.; Burdakov, D.
10.1101/2023.07.19.549648 — neuroscience — Posted on 2023-07-19
1757 Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration
Groh, J.; Abdelwahab, T.; Kattimani, Y.; Hoerner, M.; Loserth, S.; Gudi, V.; Adalbert, R.; Imdahl, F.; Saliba, A.-E.; Coleman, M.; Stangel, M.; Simons, M.; Martini, R.
10.1101/2023.07.17.549427 — neuroscience — Posted on 2023-07-19
1758 A neuronal substrate for translating nutrient state and resource density estimations into foraging decisions
Goldschmidt, D.; Tastekin, I.; Munch, D.; Park, J.-Y.; Haberkern, H.; Serra, L.; Baltazar, C.; Jayaraman, V.; Rubin, G. M.; Ribeiro, C.
10.1101/2023.07.19.549514 — neuroscience — Posted on 2023-07-19
1761 Metformin may reduce dementia risk through neuroprotection not mitigation of diabetes
Harding, E. C.; Chen, H.-J. C.; Schwiening, A.; Aggarwal, S.; Rowley, C.; Swinden, D.; Merkle, F. T.
10.1101/2023.07.18.549549 — neuroscience — Posted on 2023-07-19
1763 Sleep maintains excitatory synapse diversity in the cortex and hippocampus
Koukaroudi, D.; Qiu, Z.; Fransen, E.; Gokhale, R.; Bulovaite, E.; Komiyama, N.; Seibt, J.; Grant, S. G. N.
10.1101/2023.07.19.549645 — neuroscience — Posted on 2023-07-19
1766 Exogenous Methylglyoxal Improves Maize Yield by Alleviating Plant Diabetes and leaf senescence under Drought
Lin, Y.-H.; Zhou, Y.-N.; Jin, Y.-k.; Xiao, Z.-D.; Zhang, Y.-J.; Huang, C.; Hong, B.; Shen, S.; Zhou, S.-L.
10.1101/2023.07.18.549499 — physiology — Posted on 2023-07-19
1767 Transcriptional regulation of Dyskerin via canonical WNT signaling modulates sphingolipid biosynthesis and drives colorectal cancer.
Nigam, S.; Khan, U. K.; Praveen, A.; Shendre, A.; Carskadon, S.; Kapoor, A.; Tewari, A.; Chandra, A.; Palanisamy, N.; Ateeq, B.
10.1101/2023.07.18.549480 — cancer biology — Posted on 2023-07-19
1768 EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI
Chaudhary, N.; Choudhary, B. S.; Shivashankar, A.; Manna, S.; Ved, K.; Shaikh, S. E.; Khanna, S.; Barr, J.; Dani, J.; Verma, N.
10.1101/2023.07.17.549374 — cancer biology — Posted on 2023-07-19
1771 A Vibrating Ingestible BioElectronic Stimulator Modulates Gastric Stretch Receptors for Illusory Satiety
Srinivasan, S.; Alshareef, A. A.; Hwang, A.; Bryne, C.; Kuosmann, J.; Ishida, K.; Jenkins, J.; Liu, S.; Madani, W. A. M.; Hayward, A. M.; Fabian, N.; Traverso, G.
10.1101/2023.07.17.549257 — pathology — Posted on 2023-07-19
1772 NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer
Li, J. J.; Vasciaveo, A.; Karagiannis, D.; Sun, Z.; Chen, X.; Socciarelli, F.; Frankenstein, Z.; Zou, M.; Pannellini, T.; Chen, Y.; Gardner, K.; Robinson, B. D.; de Bono, J.; Abate-Shen, C.; Rubin, M. A.; Loda, M.; Sawyers, C. L.; Califano, A.; Lu, C.; Shen, M. M.
10.1101/2023.07.18.549585 — cancer biology — Posted on 2023-07-19
1774 Oxygen isotopes in orangutan teeth reveal recent and ancient climate variation
Smith, T. M.; Arora, M.; Austin, C.; Avila, J. N.; Duval, M.; Lim, T. T.; Piper, P.; Vaiglova, P.; Vos, J. d.; Williams, I. S.; Zhao, J.-x.; Green, D. R.
10.1101/2023.07.18.549587 — paleontology — Posted on 2023-07-19
1777 The HCM-Linked Mutation Arg92Leu in TNNT2 Allosterically Alters the cTnC-cTnI Interface and Disrupts the PKA-mediated Regulation of Myofilament Relaxation
Lynn, M. L.; Jimenez, J.; Castillo, R. L.; Klass, M. M.; Vasquez, C.; Baldo, A. P.; Gibson, C.; Murphy, A. M.; Tardiff, J. C.
10.1101/2023.07.18.549569 — biophysics — Posted on 2023-07-19
1779 Two distinct mechanisms of flavoprotein spectral tuning revealed by low-temperature and time-dependent spectroscopy
Nikolaev, A.; Tropina, E. V.; Boldyrev, K. N.; Maksimov, E. G.; Borshchevskiy, V.; Mishin, A.; Yudenko, A.; Kuzmin, A.; Kuznetsova, E.; Semenov, O.; Remeeva, A.; Gushchin, I.
10.1101/2023.07.17.549366 — biophysics — Posted on 2023-07-19
1783 Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery
Hanssen, F.; Garcia, M. U.; Folkersen, L.; Pedersen, A. S.; Lescai, F.; Jodoin, S.; Miller, E.; Wacker, O.; Smith, N.; nf-core community, ; Gabernet, G.; Nahnsen, S.
10.1101/2023.07.19.549462 — bioinformatics — Posted on 2023-07-19
1784 A Template for Translational Bioinformatics: Facilitating Multimodal Data Analyses in Preclinical Models of Neurological Injury
Gaudio, H. A.; Padmanabhan, V.; Landis, W. P.; Virgilio Silva, L. E.; Slovis, J.; Starr, J.; Weeks, M. K.; Widmann, N. J.; Forti, R. M.; Laurent, G. H.; Ranieri, N. R.; Mi, F.; Degani, R. E.; Hallowell, T.; Delso, N.; Calkins, H.; Dobrzynski, C.; Haddad, S.; Kao, S.-H.; Hwang, M.; Shi, L.; Baker, W. B.; Tsui, F.; Morgan, R. W.; Kilbaugh, T. J.; Ko, T. S.
10.1101/2023.07.17.547582 — bioinformatics — Posted on 2023-07-19
1785 Microenvironment of metastatic site reveals key predictors of PD-1 blockade response in renal cell carcinoma
Jeanneret, F.; Bazelle, P.; Schoch, S.; Pillet, C.; Um, I. H.; Bouzit, A.; Evrard, B.; Seffar, E.; Chalmel, F.; Alfaro, J. A.; Pesquita, C.; Zanzotto, F. M.; Stares, M.; Symeonides, S. N.; Laird, A.; Long, J.-A.; Descotes, J. L.; Pflieger, D.; Harrison, D. J.; Filhol, O.; Axelson, H.; Battail, C.
10.1101/2023.07.17.548676 — bioinformatics — Posted on 2023-07-19
1787 Contextualizing protein representations using deep learning on protein networks and single-cell data
Li, M. M.; Huang, Y.; Sumathipala, M.; Liang, M. Q.; Valdeolivas, A.; Ananthakrishnan, A. N.; Liao, K.; Marbach, D.; Zitnik, M.
10.1101/2023.07.18.549602 — bioinformatics — Posted on 2023-07-19
1788 Scalable querying of human cell atlases via a foundational model reveals commonalities across fibrosis-associated macrophages
Heimberg, G.; Kuo, T. C.; DePianto, D.; Heigl, T.; Diamant, N.; Salem, O.; Scalia, G.; Biancalani, T.; Rock, J.; Turley, S.; Bravo, H. C.; Kaminker, J.; Vander Heiden, J. A.; Regev, A.
10.1101/2023.07.18.549537 — bioinformatics — Posted on 2023-07-19
1789 mEthAE: an Explainable AutoEncoder for methylation data
Katz, S.; Martins dos Santos, V. A. P.; Saccenti, E.; Roshchupkin, G. V.
10.1101/2023.07.18.549496 — bioinformatics — Posted on 2023-07-19
1801 Strategy of selection and optimization of single domain antibodies targeting the PHF6 linear peptide within the Tau intrinsically disordered protein
Mortelecque, J.; Zejneli, O.; Begard, S.; Nguyen, M.; Cantrelle, F.-X.; Hanoulle, X.; Rain, J.-C.; Colin, M.; Buee, L.; Landrieu, I.; Danis, C.; Dupre, E.
10.1101/2023.07.18.549252 — biochemistry — Posted on 2023-07-19
1803 Natural disaster alters the adaptive benefits of sociality
Testard, C.; Shergold, C.; Acevedo-Ithier, A.; Hart, J.; Negron-Del Valle, J.; Philips, D.; Watowich, M.; Montague, M.; Snyder-Mackler, N. J.; Higham, J.; Platt, M.; Brent, L. J.
10.1101/2023.07.17.549328 — animal behavior and cognition — Posted on 2023-07-19
1804 Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes
Powell, S.; Liao, W.; O'Shea, C.; Kammourh, S.; Ghorbani, S.; Rigat, R.; Elahi, R.; Deans, P. M.; Le, D.; Agarwal, P.; Seow, W. Q.; Wang, K. C.; Akbarian, S.; Brennand, K.
10.1101/2023.07.17.549339 — genomics — Posted on 2023-07-19
1805 Reference genome of the ant Lasius platythorax
Feldmeyer, B.; Guiglielmoni, N.; Kirangwa, J.; Menzel, F.; Salces-Ortiz, J.; Fernandez, R.; Buena-Atienza, E.; Ciofi, C.; Diroma, M. A.; Iannucci, A.; Natali, C.; Mc Cartney, A.; Riess, O.; Casadei, N.; Waldvogel, A.-M.
10.1101/2023.07.18.549505 — genomics — Posted on 2023-07-19
1806 Modeling Type 1 Diabetes progression from single-cell transcriptomic measurements in human islets
Patil, A.; Schug, J.; Liu, C.; Lahori, D.; Descamps, H.; Naji, A.; Kaestner, K.; Faryabi, R.; Vahedi, G.
10.1101/2023.07.19.549708 — genomics — Posted on 2023-07-19
1811 The influence of marker number and sequencing depth on the ability to identify mismatch repair deficient tumours.
Law, J.; Gallon, R.; Teare, E. D.; Santibanez Koref, I.; Phelps, R.; Burn, J.; Jackson, M. S.; Santibanez-Koref, M.
10.1101/2023.07.18.546679 — genetics — Posted on 2023-07-19
1815 Taste shaped the use of botanical drugs
Leonti, M.; Baker, J.; Staub, P.; Casu, L.; Hawkins, J.
10.1101/2023.07.18.549469 — evolutionary biology — Posted on 2023-07-19
1816 Estimation of contemporary effective population size in plant populations: limitations of genomic datasets
Gargiulo, R.; Decroocq, V.; Gonzalez-Martinez, S. C.; Paz-Vinas, I.; Aury, J.-M.; Lesur Kupin, I.; Plomion, C.; Schmitt, S.; Scotti, I.; Heuertz, M.
10.1101/2023.07.18.549323 — evolutionary biology — Posted on 2023-07-19
1817 Multiple axes of visual system diversity in Ithomiini, an ecologically diverse tribe of mimetic butterflies
Wainwright, J. B.; Schofield, C.; Conway, M.; Phillips, D.; Martin-Silverstone, E.; Brodrick, E. A.; Cicconardi, F.; How, M. J.; Roberts, N. W.; Montgomery, S.
10.1101/2023.07.18.549450 — evolutionary biology — Posted on 2023-07-19
1818 Social responses to a hurricane drive greater epidemic risk
Motes-Rodrigo, A.; Albery, G. F.; Negron-Del Valle, J.; Philips, D.; Cayo Biobank Research Unit, ; Platt, M.; Brent, L. J.; Testard, C.
10.1101/2023.07.17.549341 — ecology — Posted on 2023-07-19
1824 The Plasmodium falciparum CCCH zinc finger protein MD3 regulates male gametocytogenesis through its interaction with RNA-binding proteins
Farrukh, A.; Musabyimana, J. P.; Distler, U.; Mahlich, V. J.; Mueller, J.; Bick, F.; Tenzer, S.; Pradel, G.; Ngwa, C. J.
10.1101/2023.07.19.549485 — microbiology — Posted on 2023-07-19
1825 CARs are organized in nanodomains in the plasma membrane of T cells that accumulate at tumor contact sites
Verbruggen, C.; Gehrke, L.; Banholzer, N.; Ghosh, A.; Reinhard, S.; Weber, J.; Doose, S.; Einsele, H.; Hudecek, M.; Nerreter, T.; Sauer, M.
10.1101/2023.07.19.549702 — immunology — Posted on 2023-07-19
1826 Regulation of BCR-mediated Ca2+ mobilization by MIZ1-TIMBIM4 safeguards IgG1+ GC B cell positive selection
Zhang, L.; Toboso-Navasa, A.; Gunawan, A.; Camara, A.; Nakagawa, R.; Finsterbusch, K.; Chakravarty, P.; Newman, R.; Zhang, Y.; Eilers, M.; Wack, A.; Tolar, P.; Toellner, K.-M.; Calado, D. P.
10.1101/2023.07.18.549490 — immunology — Posted on 2023-07-19
1829 Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years
Finley, A. J.; Angus, D. J.; Knight, E.; van Reekum, C. M.; Lachman, M. E.; Davidson, R. J.; Schaefer, S. M.
10.1101/2023.07.17.549371 — neuroscience — Posted on 2023-07-19
1830 Into the deep: The subthalamic and para-subthalamic nuclei in behavioral avoidance
Serra, G. P.; Guillaumin, A.; Vlcek, B.; Delagado-Zabalza, L.; Ricci, A.; Rubino, E.; Dumas, S.; Baufreton, J. M.; Georges, F.; Wallen-Mackenzie, A.
10.1101/2023.07.18.549513 — neuroscience — Posted on 2023-07-19
1831 Nonlinear manifolds underlie neural population activity during behaviour
Fortunato, C.; Bennasar-Vazquez, J.; Park, J.; Chang, J. C.; Miller, L. E.; Dudman, J. T.; Perich, M. G.; Gallego, J. A.
10.1101/2023.07.18.549575 — neuroscience — Posted on 2023-07-19
1832 A neuropsychological basis for temptation-resistant voluntary exercise
Tesmer, A. L.; Li, X.; Schmandt, C.; Polania, R.; Peleg-Raibstein, D.; Burdakov, D.
10.1101/2023.07.19.549365 — neuroscience — Posted on 2023-07-19
1833 Click-train evoked steady-state harmonic response as a novel pharmacodynamic biomarker of cortical oscillatory synchrony
Gautam, D.; Raza, M. U.; Miyakoshi, M.; Molina, J.; Joshi, Y. B.; Clayson, P. E.; Swerdlow, N.; Light, G.; Digavalli, S. V.
10.1101/2023.07.17.549322 — neuroscience — Posted on 2023-07-19
1834 Speak and you shall predict: speech at initial cocaine abstinence as a biomarker of long-term drug use behavior
Agurto, C.; Cecchi, G.; King, S. G.; Eyigoz, E. K.; Parvaz, M.; Alia-Klein, N.; Goldstein, R. Z.
10.1101/2023.07.18.549548 — neuroscience — Posted on 2023-07-19
1836 Investigating robust associations between functional connectivity based on graph theory and general intelligence
Metzen, D.; Stammen, C.; Fraenz, C.; Schlüter, C.; Johnson, W.; Güntürkün, O.; DeYoung, C. G.
10.1101/2023.07.18.549314 — neuroscience — Posted on 2023-07-19
1839 Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss
Chen, H.-J. C.; Yang, A.; Mazzaferro, S.; Mali, I.; Cahn, O.; Kentistou, K.; Rowley, C.; Stewart, N.; Seah, J. W. E.; Pisupati, V.; Kirwan, P.; Aggarwal, S.; Toyohara, T.; Florido, M. H. C.; Cowan, C. A.; Quambusch, L.; Hyvonen, M.; Livesey, M. R.; Perry, J. R. B.; Marioni, J. C.; Merkle, F. T.
10.1101/2023.07.18.549357 — neuroscience — Posted on 2023-07-19
1841 The neural and computational architecture of feedback dynamics in mouse cortex during stimulus report
Ciceri, S.; Oude Lohuis, M. N.; Rottschafer, V.; Pennartz, C.; Avitabile, D.; van Gaal, S.; Olcese, U.
10.1101/2023.07.19.549692 — neuroscience — Posted on 2023-07-19
1843 Chronic warming and dry soils limit carbon uptake and growth despite a longer growing season in beech and oak
Didion-Gency, M.; Vitasse, Y.; Buchmann, N.; Gessler, A.; Gisler, J.; Schaub, M.; Grossiord, C.
10.1101/2023.07.18.549347 — physiology — Posted on 2023-07-19
1844 Alcohol-Induced Mucociliary Dysfunction: Role of Defective CFTR Channel Function
Rasmussen, L.; Stafford, D.; LaFontaine, J.; Antony, L.; Allen, A.; Kim, H.; Raju, S. V.
10.1101/2023.07.17.548927 — pharmacology and toxicology — Posted on 2023-07-19
1846 Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner
Weiser-Evans, M. C.; Dubner, A. M.; Lu, S.; Jolly, A. J.; Strand, K. A.; Mutryn, M. F.; Hinthorn, T.; Noble, T.; Nemenoff, R. A.; Moulton, K. S.; Majesky, M. W.
10.1101/2023.07.18.549539 — pathology — Posted on 2023-07-19
1847 Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs
Cornforth, T. V.; Moyo, N. A.; Cole, S.; Lam, E.; Lobry, T.; Wolchinsky, R.; Lloyd, A.; Ward, K.; Denham, E. M.; Besra, G. S.; Veerapen, N.; Illing, P. T.; Vivian, J. P.; Raynes, J. M.; Le Nours, J.; Purcell, A. W.; Kundu, S.; Silk, J. D.; Williams, L.; Papa, S.; Rossjohn, J.; Howie, D.; Dukes, J.
10.1101/2023.07.17.548997 — cancer biology — Posted on 2023-07-19
1848 Tumor-Associated Macrophages Expand Chemoresistant, Ovarian Cancer Stem-Like Cells
Sharrow, A. C.; Ho, M.; Buj, R.; Blenman, K. R. M.; Buckanovich, R.; Aird, K. M.; Wu, L.
10.1101/2023.07.17.549067 — cancer biology — Posted on 2023-07-19
1849 A novel ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma.
Loftus, A. E. P.; Romano, M. S.; Nguyen Phuong, A.; Muir, M. T.; Dawson, J. C.; Avalle, L.; Douglas, A. T.; Mort, R. L.; Byron, A.; Carragher, N. O.; Pollard, S. M.; Brunton, V. G.; Frame, M. C.
10.1101/2023.07.19.549653 — cancer biology — Posted on 2023-07-19
1850 Heme oxygenase-1 expressing omental macrophages as a therapeutic target in ovarian high grade serous carcinoma
Spear, S.; Le Saux, O.; Mirza, H. B.; Tyson, K.; Bickel, J.; Grundland Freile, F.; Siskos, A. P.; Balcells, C.; Walton, J. B.; Woodman, C.; Ennis, D. P.; Iyer, N.; Aguirre Hernandez, C.; Xu, Y.; Spiliopoulou, P.; Brenton, J. D.; Costa-Pereira, A. P.; Keun, H. C.; Triantafyllou, E.; Arnold, J. N.; McNeish, I. A.
10.1101/2023.07.18.549474 — cancer biology — Posted on 2023-07-19
1851 Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth
Coleman, D. J. L.; Keane, P.; Luque-Martin, R.; Chin, P. S.; Blair, H.; Ames, L.; Kellaway, S. G.; Griffin, J.; Holmes, E.; Potluri, S.; Assi, S. A.; Bushweller, J. H.; Heidenreich, O. T.; Cockerill, P.; Bonifer, C.
10.1101/2023.07.18.549495 — cancer biology — Posted on 2023-07-19
1852 Benchmarking and optimization of cell-free DNA deconvolution
Hill, T.; Redekar, N. R.; Andargie, T. E.; Jang, M. K.; Agbor-Enoh, S.
10.1101/2023.07.17.549353 — bioinformatics — Posted on 2023-07-19
1854 Understanding the structural basis for differential binding of lapachol with PfHSP70s
Singh, B.; Kaur, S.; Sandhu, K. K.; Nainani, C.; Upadhyay, V.; Hora, R.; Mishra, P. C.
10.1101/2023.07.18.549604 — bioinformatics — Posted on 2023-07-19
1858 A Versatile Photocrosslinkable Silicone Composite for 3D Printing Applications
Alioglu, M. A.; Yilmaz, Y. O.; Gerhard, E. M.; Pal, V.; Gupta, D.; Rizvi, H.; Ozbolat, I. T.
10.1101/2023.07.17.549429 — bioengineering — Posted on 2023-07-19
1859 Harnessing Gradients for Self-Assembly of Peptide-Based Nanocapsules: A Pathway to Advanced Drug Delivery Systems
Li, H.; Qian, X.; Mohanram, H.; Han, X.; Qi, H.; Zou, G.; Yuan, F.; Miserez, A. G. T.; Yang, Q.; Liu, T.; Gao, H.; Yu, J.
10.1101/2023.07.19.549672 — bioengineering — Posted on 2023-07-19
1861 Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
Byrne, A.; Le, D.; Sereti, K.; Menon, H.; Patel, N.; Lund, J.; Xavier-Magalhaes, A.; Shi, M.; Sterne-Weiler, T.; Modrusan, Z.; Stephenson, W.
10.1101/2023.07.17.549422 — genomics — Posted on 2023-07-19
1862 T2T-YAO: a Telomere-to-telomere Assembled Diploid Reference Genome for Han Chinese
He, Y.; Chu, Y.; Guo, S.; Hu, J.; Li, R.; Zheng, Y.; Ma, X.; Du, Z.; Zhao, L.; Yu, W.; Xue, J.; Bian, W.; Yang, F.; Chen, X.; Zhang, P.; Wu, R.; Ma, Y.; Shao, C.; Chen, J.; Wang, J.; Li, J.; Wu, J.; Hu, X.; Long, Q.; Jiang, M.; Ye, H.; Song, S.; Li, G.; Wei, Y.; Xu, Y.; Ma, Y.; Chen, Y.; Wang, K.; Bao, J.; Xi, W.; Wang, F.; Ni, W.; Zhang, M.; Yu, Y.; Li, S.; Kang, Y.; Gao, Z.
10.1101/2023.07.17.549286 — genetics — Posted on 2023-07-19
1863 afila, the origin and nature of a major innovation in the history of pea breeding
Tayeh, N.; Hofer, J.; Aubert, G.; Jacquin, F.; Turner, L.; Kreplak, J.; Paajanen, P.; Le Signor, C.; Dalmais, M.; Pflieger, S.; Geffroy, V.; Ellis, N.; Burstin, J.
10.1101/2023.07.19.549624 — genetics — Posted on 2023-07-19
1870 Contribution of carbon inputs to soil carbon accumulation cannot be neglected
He, X.; Abramoff, R.; Abs, E.; Georgiou, K.; Zhang, H.; Goll, D. S.
10.1101/2023.07.17.549330 — ecology — Posted on 2023-07-19
1871 Biogeographic context mediates multifaceted diversity-productivity relationships in island and mainland forests
Tolmos, M. L.; Guerrero-Ramirez, N. R.; Ameztegui, A.; Barajas Barbosa, M. P.; Craven, D.; Kreft, H.
10.1101/2023.07.17.549319 — ecology — Posted on 2023-07-19
1874 Mapping and targeting of C1ql1-expressing cells in the mouse
Moghimyfiroozabad, S.; Paul, M. A.; Sigoillot, S. M.; Selimi, F.
10.1101/2023.07.17.549329 — neuroscience — Posted on 2023-07-19
1875 Multiple objects evoke fluctuating responses in several regions of the visual pathway
Schmehl, M. N.; Caruso, V. C.; Chen, Y.; Jun, N. Y.; Willett, S. M.; Mohl, J. T.; Ruff, D. A.; Cohen, M. R.; Ebihara, A.; Freiwald, W.; Tokdar, S. T.; Groh, J. M.
10.1101/2023.07.19.549668 — neuroscience — Posted on 2023-07-19
1879 DNA methylation sites in early adulthood characterised by pubertal timing and development: A twin study
Sehovic, E.; Zellers, S. M.; Youssef, M. K.; Heikkinen, A.; Kaprio, J.; Ollikainen, M.
10.1101/2023.07.17.549162 — genomics — Posted on 2023-07-19
1882 A Plant Flavonol Rescues a Pathogenic Mutation Associated with Kinesin in Neurons
Chai, Y.; Li, D.; Gong, W.; Ke, J.; Tian, D.; Chen, Z.; Guo, A.; Guo, Z.; Li, W.; Feng, W.; Ou, G.
10.1101/2023.07.19.548188 — cell biology — Posted on 2023-07-19
1883 Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth
Tran, H.; Frank, D.; Bergamasco, M.; Mlodzianoski, M.; Kueh, A.; Tsui, E.; Hall, C.; Kastrappis, G.; Voss, A. K.; McLean, C.; Faux, M. C.; Rogers, K.; Tran, B.; Vincan, E.; Komander, D.; Dewson, G.
10.1101/2023.07.17.549243 — cell biology — Posted on 2023-07-19
1884 Cold temperature induces a TRPM8-independent calcium release from the endoplasmic reticulum in human platelets
Stratiievska, A.; Filippova, O.; Ozpolat, T.; Byrne, D.; Bailey, S. L.; Mollica, M. Y.; Harris, J.; Esancy, K.; Chen, J.; Dhaka, A.; Sniadecki, N. J.; Lopez, J. A.; Stolla, M.
10.1101/2023.07.19.549670 — cell biology — Posted on 2023-07-19
1886 The cellular landscape of the endochondral bone highlights its multipotent and immunomodulatory features during the transition to extrauterine life
Rueda, A. D.; Salvador-Martinez, I.; Sospedra-Arrufat, I.; Alcaina-Caro, A.; Fernandez-Minan, A.; Burgos-Ruiz, A. M.; Cases, I.; Mohedano, A.; Tena, J. J.; Heyn, H.; Lopez-Rios, J.; Nusspaumer, G.
10.1101/2023.07.18.549529 — cell biology — Posted on 2023-07-19
1889 High resolution spatial investigation of intracellular oxygen in muscle cells.
Penjweini, R.; Pasut, A.; Roarke, B.; Alspaugh, G.; Sackett, D. L.; Knutson, J. R.
10.1101/2023.07.18.548845 — cell biology — Posted on 2023-07-19
1891 C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types
Broce, I.; Sirkis, D.; Nillo, R. M.; Bonham, L. W.; Lee, S. E.; Miller, B. L.; Sturm, V.; Sugrue, L. S.; Desikan, R.; Yokoyama, J. S.
10.1101/2023.07.17.549377 — neuroscience — Posted on 2023-07-19
1894 Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress
Martinez-Ruiz, L.; Florido, J.; Rodriguez-Santana, C.; Lopez-Rodriguez, A.; Guerra-Librero, A.; Fernandez-Gil, B. I.; Garcia-Tarraga, P.; Garcia-Verdugo, J. M.; Oppel, F.; Sudhoff, H.; Sanchez-Porras, D.; Ten-Esteve, A.; Fernandez-Martinez, J.; Gonzalez-Garcia, P.; Rusanova, I.; Acuna-Castroviejo, D.; Carriel, V. S.; Escames, G.
10.1101/2023.07.17.549311 — cancer biology — Posted on 2023-07-19
1896 Methods for making and observing model lipid droplets
Gandhi, S. A.; Parveen, S.; Alduhailan, M.; Tripathi, R. C.; Junedi, N.; Saqallah, M.; Sanders, M. A.; Hoffmann, P. M.; Truex, K.; Granneman, J. G.; Kelly, C. V.
10.1101/2023.07.17.549385 — biophysics — Posted on 2023-07-19
1897 Cell viability is dominated by quantum effects
Yasuda, T.; Nakajima, N.; Yanaka, T.; Gotoh, T.; Kagawa, W.; Sugasawa, K.; Tajima, K.
10.1101/2023.07.18.549596 — biophysics — Posted on 2023-07-19
1900 Microfluidic organotypic device to test intestinal mucosal barrier permeability ex vivo
Cherwin, A. E.; Templeton, H. N.; Ehrlich, A. T.; Patlin, B. H.; Henry, C. S.; Tobet, S. A.
10.1101/2023.07.18.549546 — bioengineering — Posted on 2023-07-19
1902 The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging
Egan, B. M.; Pohl, F.; Anderson, X.; Williams, S. C.; Adodo, I. G.; Hunt, P.; Wang, Z.; Chiu, C.-H.; Scharf, A.; Mosley, M.; Kumar, S.; Schneider, D. L.; Fujiwara, H.; Hsu, F.-F.; Kornfeld, K.
10.1101/2023.07.17.549402 — developmental biology — Posted on 2023-07-19
1903 Cardiomyocyte mechanical memory is regulated through the talin interactome and DLC1 dependent regulation of RhoA
Marhuenda, E.; Xanthis, I.; Pandey, P.; Azad, A.; Richter, M.; Pavlovic, D.; Gehmlich, K.; Faggian, G.; Ehler, E.; Levitt, J.; Ameer-Beg, S.; Iskratsch, T.
10.1101/2023.07.19.549635 — cell biology — Posted on 2023-07-19
1904 Visuomotor experience induces functional and structural plasticity of chandelier cells
Seignette, K.; Jamann, N.; Papale, P.; Terra, H.; Porneso, R. P. O.; de Kraker, L.; van der Togt, C.; van der Aa, M.; Neering, P.; Ruimschotel, E.; Roelfsema, P. R.; Montijn, J. S.; Self, M. W.; Kole, M. H. P.; Levelt, C. N.
10.1101/2023.04.21.537780 — neuroscience — Posted on 2023-07-19
1906 Optical Control of G-Actin with a Photoswitchable Latrunculin
Veprek, N. A.; Cooper, M. H.; Laprell, L.; Yang, E. J.-N.; Folkerts, S.; Bao, R.; Oertner, T. G.; Pon, L. A.; Zuchero, J. B.; Trauner, D. H.
10.1101/2023.07.17.549222 — pharmacology and toxicology — Posted on 2023-07-19
1910 Perturbations of glutathione and sphingosine metabolites in Port Wine Birthmark patient-derived induced pluripotent stem cells
Nguyen, V.; Kravitz, J.; Gao, C.; Hochman, M. L.; Meng, D.; Chen, D.; Wang, Y.; Jegga, A. G.; Nelson, S.; Tan, W.
10.1101/2023.07.18.549581 — cell biology — Posted on 2023-07-19
1911 Decoding the content of working memory in school-aged children
Turoman, N.; Fiave, P. A.; Zahnd, C.; deBettencourt, M. T.; Vergauwe, E.
10.1101/2023.02.10.527990 — neuroscience — Posted on 2023-07-19
1913 Staying in control: characterising the mechanisms underlying cognitive control in high and low arousal states
Alameda, C.; Avancini, C.; Sanabria, D.; Bekinschtein, T. A.; Canales-Johnson, A.; Ciria, L. F.
10.1101/2023.04.17.536548 — neuroscience — Posted on 2023-07-19
1915 Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif
Brkic, A.; Leibundgut, M.; Jablonska, J.; Zanki, V.; Car, Z.; Petrovic-Perokovic, V.; Marsavelski, A.; Ban, N.; Gruic-Sovulj, I.
10.1101/2023.01.31.526100 — biochemistry — Posted on 2023-07-19
1919 BRAIDing receptors for cell specific targeting
Chen, H.; Lee, S.-J.; Li, R.; Sura, A.; Suen, N.; Dilip, A.; Pomogov, Y.; Vuppalapaty, M.; Lu, C.; Post, Y.; Li, Y.
10.1101/2023.07.18.549566 — synthetic biology — Posted on 2023-07-18
1920 R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription
LaMarca, E. A.; Saito, A.; Plaza-Jennings, A.; Hellmich, A.; Fernando, M. B.; Javidfar, B.; Espeso-Gil, S.; Estill, M.; Liao, W.; Townsley, K.; Florio, A.; Ethridge, J. E.; Do, C.; Tycko, B.; Shen, L.; Kamiya, A.; Tsankova, N. M.; Brennand, K. J.; Akbarian, S.
10.1101/2023.07.18.549494 — genomics — Posted on 2023-07-18
1921 Development of potent dual BET/HDAC inhibitors via pharmacophore merging and structure-guided optimization
Bauer, N.; Balourdas, D.-I.; Schneider, J. R.; Zhang, X.; Berger, L. M.; Berger, B.-T.; Klopp, N. A.; Siveke, J. T.; Knapp, S.; Joerger, A. C.
10.1101/2023.07.18.547334 — biochemistry — Posted on 2023-07-18
1923 Tur1 regulates alternative TSS usage in Cryptococcus
Dang, T. T. V.; Maufrais, C.; Colin, J.; Moyrand, F.; Mouyna, I.; Coppee, J.-Y.; Onyishi, C. U.; Lipecka, J.; Guerrera, I. C.; May, R. C.; Janbon, G.
10.1101/2023.07.18.549460 — molecular biology — Posted on 2023-07-18
1925 Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice
Ouwendijk, W. J.; Roychoudhury, P.; Cunningham, A. L.; Jerome, K. R.; Koelle, D. M.; Kinchington, P. R.; Mohr, I.; Wilson, A. C.; Verjans, G. M. G. M.; Depledge, D. P.
10.1101/2023.07.17.549345 — microbiology — Posted on 2023-07-18
1926 Phage inducible chromosomal minimalist island (PICMI), a family of satellites of marine virulent phages
Barcia-Cruz, R.; Goudenege, D.; Moura de Sousa, J. A.; Piel, D.; Marbouty, M.; Rocha, E.; Le Roux, F.
10.1101/2023.07.18.549517 — microbiology — Posted on 2023-07-18
1927 A host AAA-ATPase exhibits bacteriolytic activity for clearance of microbial infection
Ghosh, S.; Roy, S.; Baid, N.; Das, U. K.; Hajra, D.; Menon, S.; Sahil, M.; Shaw, S.; Rakshit, S.; Rajmani, R. S.; Adicherla, H.; Mondal, J.; Chakravortty, D.; Banerjee, A.
10.1101/2023.07.18.549519 — microbiology — Posted on 2023-07-18
1929 Taxonomy of Pseudomonas spp determines interactions with Bacillus subtilis
Lyng, M.; Thorisdottir, B.; Sveinsdottir, S. H.; Hansen, M. L.; Maroti, G.; Jelsbak, L.; Kovacs, A. T.
10.1101/2023.07.18.549276 — microbiology — Posted on 2023-07-18
1930 Fitness Tradeoffs of Multidrug Efflux Pumps in Escherichia coli K-12 in Acid or Base, and with Aromatic Phytochemicals
Liu, Y.; Van Horn, A. M.; Pham, M. T. N.; Dinh, B. N. N.; Chen, R.; Raphael, S. D. R.; Paulino, A.; Thaker, K.; Somadder, A.; Menke, C. C.; Slimak, Z. C.; Slonczewski, J. L.
10.1101/2023.07.17.549369 — microbiology — Posted on 2023-07-18
1931 Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
Egan, M. S.; O'Rourke, E. A.; Mageswaran, S. K.; Zuo, B.; Martynyuk, I.; Demissie, T.; Hunter, E. N.; Bass, A. R.; Chang, Y.-W.; Brodsky, I. E.; Shin, S.
10.1101/2023.07.17.549348 — microbiology — Posted on 2023-07-18
1935 Identification of endothelial-to-mesenchymal transition gene signatures in single-cell transcriptomics of human atherosclerotic tissue
Slenders, L.; Wesseling, M.; Boltjes, A.; Kapteijn, D.; Depuydt, M. A.; Prange, K. H.; van den Dungen, N. A. M.; Benavente, E. D.; De Kleijn, D.; de Borst, G. J.; Den Ruijter, H. M.; Owens, G. K.; Mokry, M.; Pasterkamp, G.
10.1101/2023.07.18.549599 — molecular biology — Posted on 2023-07-18
1936 Development and Validation of a multi-target TaqMan qPCR method for detection of Borrelia burgdorferi sensu lato
Masseglia, S.; Rene-Martellet, M.; Rates, M.; Hizo-Teufel, C.; Fingerle, V.; Margos, G.; Bailly, X.
10.1101/2023.07.18.549442 — molecular biology — Posted on 2023-07-18
1942 Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens
Vollenweider, V.; Rehm, K.; Chepkirui, C.; Perez-Berlanga, M.; Polymenidou, M.; Piel, J.; Bigler, L.; Kuemmerli, R.
10.1101/2023.07.18.549568 — microbiology — Posted on 2023-07-18
1947 Scalable projected Light Sheet Microscopy for high-resolution imaging of living and cleared samples
Chen, Y.; Chauhan, S.; Gong, C.; Dayton, H.; Xu, C.; De La Cruz, E. D.; Datta, M. S.; Leong, K. W.; Dietrich, L. E. P.; Tomer, R.
10.1101/2023.05.31.543173 — neuroscience — Posted on 2023-07-18
1949 A laboratory framework for ongoing optimisation of amplification based genomic surveillance programs
Lam, C.; Johnson-Mackinnon, J.; Basile, K.; Fong, W.; Suster, C. J. E.; Gall, M.; Aguis, J.; Chandra, S.; Draper, J.; Martinez, E.; Drew, A.; Wang, Q.; Chen, S.; Kok, J.; Dwyer, D. L.; Sintchenko, V.; Rockett, R. J.
10.1101/2023.07.17.549425 — genomics — Posted on 2023-07-18
1950 SPLASH: a statistical, reference-free genomic algorithm unifies biological discovery
Chaung, K.; Baharav, T. Z.; Henderson, G.; Wang, P.; Zheludev, I. N.; Salzman, J.
10.1101/2023.07.17.549408 — genomics — Posted on 2023-07-18
1952 Influence of circular RNA topology on Target RNA-Directed MicroRNA Degradation
Fuchs Whightman, F.; Lukin, J.; Giusti, S.; Soutschek, M.; Bragado, L.; Pozzi, B.; Gonzalez, P.; Fededa, J. P.; Schratt, G.; Fujiwara, R.; Wilusz, J. E.; Refojo, D.; de la Mata, M.
10.1101/2022.04.11.487822 — molecular biology — Posted on 2023-07-18
1953 ACE2 mimetic antibody potently neutralizes all SARS-CoV-2 variants and fully protects in XBB.1.5 challenged monkeys
Fenwick, C.; Turelli, P.; Duhoo, Y.; Lau, K.; Herate, C.; Marlin, R.; Lamrayah, M.; Campos, J.; Leuenberger, L.; Farina, A.; raclot, c.; Genet, V.; Fiscalini, F.; Cesborn, J.; Perez, L.; Bosquet, N.; Contreras, V.; Lheureux, K.; relouzat, f.; Abdelnabi, R.; Foo, C. S.-Y.; Neyts, J.; leyssen, p.; Levy, Y.; Pojer, F.; Stahlberg, H.; Le Grand, R.; Trono, D.; Pantaleo, G.
10.1101/2023.07.18.549530 — microbiology — Posted on 2023-07-18
1954 Deep mutational scanning of whole SARS-CoV-2 spike in an inverted infection system
Taminishi, S.; Li, S.; Higuchi, Y.; Kirita, Y.; Motooka, D.; Ozaki, Y.; Arimori, T.; Ikemura, N.; Ito, Y.; Matoba, S.; Okamoto, T.; Takagi, J.; Standley, D. M.; Hoshino, A.
10.1101/2023.07.17.549430 — microbiology — Posted on 2023-07-18
1957 zol & fai: large-scale targeted detection and evolutionary investigation of gene clusters
Salamzade, R.; Tran, P. Q.; Martin, C.; Manson, A. L.; Gilmore, M. S.; Earl, A. M.; Anantharaman, K.; Kalan, L.
10.1101/2023.06.07.544063 — bioinformatics — Posted on 2023-07-18
1958 The membrane-cytoplasmic linker defines activity of FtsH proteases in Pseudomonas aeruginosa clone C
Mawla, G. D.; Kamal, S. M.; Cao, L.; Purhonen, P.; Hebert, H.; Sauer, R. T.; Baker, T. A.; Romling, U.
10.1101/2023.06.19.545564 — biochemistry — Posted on 2023-07-18
1963 A high-throughput multiplex array for antigen-specific serology with automated analysis.
Rosenberg, A. F.; Killian, J. T.; Green, T. J.; Akther, J.; Hossain, E.; Qiu, S.; Yang, G.; Randall, T. D.; Lund, F. E.; King, R. G.
10.1101/2023.03.29.534777 — immunology — Posted on 2023-07-18
1964 Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Parmasad, J.-L. A.; Ricke, K. M.; Stykel, M. G.; Buchner-Duby, B.; Nguyen, B.; Bruce, A.; Geertsma, H. M.; Lian, E.; Lengacher, N. A.; Callaghan, S. M.; Joselin, A.; Tomlinson, J. J.; Schlossmacher, M. G.; Stanford, W. L.; Ma, J.; Brundin, P.; Ryan, S. D.; Rousseaux, M. W. C.
10.1101/2022.05.02.490309 — neuroscience — Posted on 2023-07-18
1967 Mapping neuroinflammation in vivo with diffusion-MRI in rats given a systemic lipopolysaccharide challenge
Kim, E.; Carreira Figueiredo, I.; Simmons, C.; Randall, K.; Rojo Gonzalez, L.; Wood, T. C.; Ranieri, B.; Sureda-Gibert, P.; Howes, O.; Pariante, C.; NIMA Consortium, ; Pasternak, O.; Dell'Acqua, F.; Turkheimer, F. E.; Cash, D.
10.1101/2022.11.22.517484 — neuroscience — Posted on 2023-07-18
1969 Single-cell analysis of the nervous system at small and large scales with instant partitions
Frazel, P.; Fricano-Kugler, C.; May-Zhang, A. A.; O'Dea, M. R.; Prakash, P.; Desmet, N.; Lee, H.; Meltzer, R. H.; Fontanez, K.; Hettige, P.; Agam, Y.; Lithwick-Yanai, G.; Lipson, D.; Luikart, B. W.; Dasen, J. S.; Liddelow, S.
10.1101/2023.07.14.549051 — neuroscience — Posted on 2023-07-18
1975 An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering
Cui, G.; Botuyan, M. V.; Drane, P.; Hu, Q.; Bragantini, B.; Thompson, J. R.; Schuller, D. J.; Detappe, A.; Perfetti, M. T.; James, L. I.; Frye, S. V.; Chowdhury, D.; Mer, G.
10.1101/2023.04.20.534960 — biochemistry — Posted on 2023-07-18
1976 Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases
Venkat, A.; Watterson, G.; Byrne, D. P.; Boyle, B. O.; Shrestha, S.; Gravel, N.; Fairweather, E. E.; Daly, L. A.; Bunn, C.; Yeung, W.; Aggarwal, I.; Katiyar, S.; Eyers, C. E.; Eyers, P.; Kannan, N.
10.1101/2023.03.29.534689 — evolutionary biology — Posted on 2023-07-18
1978 Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery
Wallace, N. S.; Gadbery, J. E.; Cohen, C. I.; Kendall, A. K.; Jackson, L. P.
10.1101/2023.07.18.549521 — cell biology — Posted on 2023-07-18
1979 Optimal frequency of perinatal retinal waves is essential for the precise wiring of visual axons in non-image forming nuclei
Negueruela, S.; Morenilla-Palao, C.; Sala, S.; Herrera, M.; Coca, Y.; Lopez-Cascales, M. T.; Ordono, P.; Florez-Paz, D. M.; Herrera, E.; Gomis, A.
10.1101/2022.07.27.501692 — neuroscience — Posted on 2023-07-18
1980 Regulatory start-stop elements in 5' untranslated regions pervasively modulate translation
Rendleman, J.; Haizel, S.; Wu, S.; Ge, X.; Liu, J.; Zou, H.; Mohammad, M. P.; Pressler, M.; Maity, S.; Hronova, V.; Gao, Z.; Herrmannova, A.; Lei, A.; Allgoewer, K.; Sultanov, D.; Hinckley, W. E.; Szkop, K.; Topisirovic, I.; Larsson, O.; Hatzoglou, M.; Valasek, L. S.; Vogel, C.
10.1101/2021.07.26.453809 — systems biology — Posted on 2023-07-18
1981 Non-cell autonomous cardiomyocyte regulation complicates gene supplementation therapy for LMNA cardiomyopathy
Sun, Y.; Guo, C.; Chen, Z.; Lin, J.; Yang, L.; Zhang, Y.; Wu, C.; Zhao, D.; Jardin, B.; Pu, W.; Zhao, M.; Dong, E.; Hu, X.; Zhang, S.; Guo, Y.
10.1101/2023.07.18.549413 — cell biology — Posted on 2023-07-18
1982 ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin
Cacho-Navas, C.; Lopez-Pujante, C.; Reglero-Real, N.; Colas-Algora, N.; Cuervo, A.; Conesa, J. J.; Barroso, S.; Ciordia, S.; Paradela, A.; D'Agostino, G.; Manzo, C.; Feito, J.; Andres, G.; Correas, I.; Carazo, J. M.; Nourshargh, S.; Huch, M.; Millan, J.
10.1101/2023.07.18.549509 — cell biology — Posted on 2023-07-18
1983 S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry
Mohammed, T. O.; Lin, Y.-R.; Weissenbruch, K.; Ngo, K. X.; Zhang, Y.; Kodera, N.; Bastmeyer, M.; Miyanari, Y.; Taoka, A.; Franz, C. M.
10.1101/2023.07.17.549432 — cell biology — Posted on 2023-07-18
1984 A signalling rheostat controls chromosome segregation fidelity during early lineage specification and neurogenesis by modulating DNA replication stress
de Jaime Soguero, A.; Hattemer, J.; Haas, A.; Bufe, A.; Di Marco, B.; Bohly, N.; Landry, J. J. M.; Schoell, B.; Rosa, V. S.; Villacorta, L.; Baskan, Y.; Androulaki, S.; Trapp, M.; Benes, V.; Das, B.; Shahbazi, M.; Jauch, A.; Engel, U.; Patrizi, A.; Sotillo, R.; Bageritz, J.; Alfonso, J.; Bastians, H.; Acebron, S. P.
10.1101/2023.07.18.549463 — cell biology — Posted on 2023-07-18
1985 SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression
Fletcher-Jones, A.; Spackman, E.; Craig, T. J.; Nakamura, Y.; Wilkinson, K. A.; Henley, J. M.
10.1101/2023.07.18.549510 — neuroscience — Posted on 2023-07-18
1987 A Systematic Identification of RBPs Driving Aberrant Splicing in Cancer
Gimeno, M.; Lobato, C.; San Martin, A.; Anorbe, A.; Rubio, A.; Ferrer-Bonsoms, J. A.
10.1101/2023.07.17.549307 — bioinformatics — Posted on 2023-07-18
1988 An epigenome-wide association study of child appetitive traits and DNA methylation
Harris, H. A.; Friedman, C.; Starling, A.; Dabelea, D.; Johnson, S. L.; Fuemmeler, B. F.; Jima, D.; Murphy, S. K.; Hoyo, C.; Jansen, P. W.; Felix, J.; Mulder, R. H.
10.1101/2023.07.17.549289 — genetics — Posted on 2023-07-18
1990 Contrasting Patterns of Pierce's Disease Risk in European Vineyards Under Global Warming
Gimenez-Romero, A.; Iturbide, M.; Moralejo, E.; Gutierrez, J. M.; Matias, M. A.
10.1101/2023.07.17.549293 — ecology — Posted on 2023-07-18
1991 High-dimensional spectral cytometry panels for whole blood immune phenotyping
Dott, T.; Culina, S.; Chemali, R.; Ait Mansour, C.; Dubois, F.; Jagla, B.; Doisne, J. M.; Rogge, L.; Huetz, F.; Jönsson, F.; Commere, P.-H.; Di Santo, J.; Terrier, B.; Quintana-Murci, L.; Duffy, D.; Hasan, M.; Milieu Interieur Consortium,
10.1101/2023.07.17.549272 — immunology — Posted on 2023-07-18
1992 An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
Houbaert, D.; Nikolakopoulos, A. P.; Mece, O.; Jacobs, K.; Roels, J.; Shankar, G.; Agrawal, M.; More, S.; Ganne, M.; Rillaerts, K.; Boon, L.; Swoboda, M.; Nobis, M.; Mourao, L.; Bosisio, F. M.; Vandamme, N.; Bergers, G.; Scheele, C.; Agostinis, P.
10.1101/2023.07.17.549282 — immunology — Posted on 2023-07-18
1996 A 7T interleaved fMRS and fMRI study on visual contrast dependency in the human brain.
Schrantee, A.; Najac, C.; Jungerius, C.; van der Zwaag, W.; Jbabdi, S.; Clarke, W. T.; Ronen, I.
10.1101/2023.07.17.548989 — neuroscience — Posted on 2023-07-18
1997 Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation
Dagnino, P. C.; Escrichs, A.; Lopez-Gonzalez, A.; Gosseries, O.; Annen, J.; Sanz Perl, Y.; L. Kringelbch, M.; Laureys, S.; Deco, G.
10.1101/2023.07.17.549269 — neuroscience — Posted on 2023-07-18
1999 In vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men
Talwar, P.; Deantoni, M. A.; Van Egroo, M.; Muto, V.; Chylinski, D.; Koshmanova, E.; Jaspar, M.; Meyer, C.; Degueldre, C.; Berthomier, C.; Luxen, A.; Salmon, E.; Collette, F.; Dijk, D.-J.; Schmidt, C.; Phillips, C.; Maquet, P.; Sherif, S.; Vandewalle, G.
10.1101/2023.07.17.549285 — neuroscience — Posted on 2023-07-18
2001 In situ cryo-electron tomography of beta-amyloid and tau in post-mortem Alzheimer's disease brain
Gilbert, M. A. G.; Fatima, N.; Jenkins, J.; O'Sullivan, T. J.; Schertel, A.; Halfon, Y.; Morrema, T. H. J.; Geibel, M.; Radford, S. E.; Hoozemans, J. J. M.; Frank, R. A. W.
10.1101/2023.07.17.549278 — pathology — Posted on 2023-07-18
2002 EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive State
Wu, N. C.; Quevedo, R.; Nurse, M.; Hezaveh, K.; Liu, H.; Sun, F.; Muffat, J.; Sun, Y.; Simmons, C. A.; McGaha, T. L.; Prinos, P.; Arrowsmith, C. H.; Ailles, L.; D'Arcangelo, E.; McGuigan, A. P.
10.1101/2023.07.17.549300 — cancer biology — Posted on 2023-07-18
2007 Reprogramming Yarrowia lipolytica metabolism for efficient synthesis of itaconic acid from flask to semi-pilot scale
Fu, J.; Zaghen, S.; Lu, H.; Konzock, O.; Poorinmohammad, N.; Kornberg, A.; Koseto, D.; Wentzel, A.; Bartolomeo, F. D.; Kerkhoven, E. J.
10.1101/2023.07.17.549194 — bioengineering — Posted on 2023-07-18
2012 Chromosome level assembly of wild spinach provides insights into the divergence of homo- and heteromorphic plant sex-chromosomes.
Severing, E. I.; van der Werf, E.; van Kaauwen, M. P. W.; Kodde, L.; Kik, C.; van Treuren, R.; Visser, R. G. F.; Finkers, R.; Bai, Y.
10.1101/2023.07.17.549201 — evolutionary biology — Posted on 2023-07-18
2016 Cell networks in the mouse liver during partial hepatectomy
Li, B.; Rodrigo-Torres, D.; Pelz, C.; Innes, B. T.; Canaday, P.; Chai, S.; Zandstra, P.; Bader, G.; Grompe, M.
10.1101/2023.07.16.549116 — cell biology — Posted on 2023-07-18
2017 Protective intravenous BCG vaccination induces enhanced immune signaling in the airways
Peters, J. M.; Irvine, E. B.; Rosenberg, J. M.; Wadsworth, M. H.; Hughes, T. K.; Sutton, M.; Nyquist, S. K.; Bromley, J. D.; Mondal, R.; Roederer, M.; Seder, R.; Darrah, P. A.; Flynn, J. L.; Shalek, A. K.; Fortune, S. M.; Bryson, B. D.
10.1101/2023.07.16.549208 — immunology — Posted on 2023-07-18
2019 Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories
Torres-Espin, A.; Rabadaugh, H.; Fitzsimons, S.; Chou, A.; Harvey, D.; Lindberg, C.; Goldberger, L.; Casaletto, K. B.; Staffaroni, A.; Maillard, P.; Miller, B. L.; Hinman, J. D.; DeCarli, C.; Ferguson, A. R.; Kramer, J.; Elahi, F. M.
10.1101/2023.07.16.549192 — neuroscience — Posted on 2023-07-18
2020 iPSC-Astrocyte morphology reflects patient clinical markers
Rowland, H. A.; Miller, G.; Liu, Q.; Sharp, N. R.; Ng, B.; Wei, T.; Arunasalam, K.; Koychev, I.; Hedegaard, A.; Ribe, E. M.; Chan, D.; Chessell, T.; Kocagoncu, E.; Lawson, J.; Malhotra, P. A.; Ridha, B. H.; Rowe, J. B.; Thomas, A. J.; Zamboni, G.; Zetterberg, H.; Cader, Z.; Wade-Martins, R.; Lovestone, S.; Nevado Holgado, A.; Kormilitzin, A.; Buckley, N. J.
10.1101/2023.07.15.548687 — neuroscience — Posted on 2023-07-18
2024 Altered TFEB subcellular localization in nigral dopaminergic neurons of subjects with prodromal, sporadic and GBA-related Parkinson's disease and Dementia with Lewy bodies
Morella, M. L.; Moors, T. E.; Bertran-Cobo, C.; Geut, H.; Udayar, V.; Timmermans-Huisman, E.; Ingrassia, A. M.; Breve, J. J.; Bol, J. G.; Bonifati, V.; Jagasia, R.; van de Berg, W. D.
10.1101/2023.07.16.549189 — neuroscience — Posted on 2023-07-18
2033 Electrical spiking activity of proteinoids-ZnO colloids
Mougkogiannis, P.; Raeisi Kheirabadi, N.; Chiolerio, A.; Adamatzky, A.
10.1101/2023.07.15.549138 — biophysics — Posted on 2023-07-18
2034 An In-Silico Testbed for Fast and Accurate MR Labeling of Orthopaedic Implants
Noetscher, G. M.; Serano, P. J.; Horner, M.; Prokop, A.; Hanson, J.; Fujimoto, K.; Brown, J. E.; Nazarian, A.; Ackerman, J.; Makaroff, S. N.
10.1101/2023.07.16.549234 — biophysics — Posted on 2023-07-18
2039 Mycobacterium tuberculosis infection associated immune perturbations correlate with antiretroviral immunity
Tepekule Mueller, B.; Joerimann, L.; Schenkel, C. D.; Opitz, L.; Tschumi, J.; Wolfensberger, R.; Neumann, K.; Kusejko, K.; Zeeb, M.; Boeck, L.; Kaelin, M.; Notter, J.; Furrer, H.; Hoffmann, M.; Hirsch, H. H.; Calmy, A.; Cavassini, M.; Labhardt, N. D.; Bernasconi, E.; Metzner, K. J.; Braun, D. L.; Guenthard, H. F.; Kouyos, R. D.; Duffy, F.; Nemeth, J.; the Swiss HIV Cohort Study,
10.1101/2023.07.14.548872 — immunology — Posted on 2023-07-18
2040 Prior probability cues bias sensory encoding with increasing task exposure
Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.
10.1101/2023.07.15.549123 — neuroscience — Posted on 2023-07-18
2043 Biomimetic computer-to-brain communication restoring naturalistic touch sensations via peripheral nerve stimulation
Valle, G.; Katic Secerovic, N.; Eggemann, D.; Gorskii, O.; Pavlova, N.; Cvancara, P.; Stieglitz, T.; Musienko, P.; Bumbasirevic, M.; Raspopovic, S.
10.1101/2023.07.15.549130 — neuroscience — Posted on 2023-07-18
2044 Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles
Brahmer, A.; Geiss, C.; Lygeraki, A.; Neuberger, E.; Tzaridis, T.; Nguyen, T. T.; Luessi, F.; Regnier-Vigouroux, A.; Hartmann, G.; Simon, P.; Endres, K.; Bittner, S.; Reiners, K. S.; Kramer-Albers, E.-M.
10.1101/2023.07.14.549082 — neuroscience — Posted on 2023-07-18
2045 Proteomic analysis reveals APOE isoform-specific regulation of ribosomes in neural precursor cells
M, S.; Paul, P.; Ramakrishna, S.; Ghose, V.; Dey, G.; Muddashetty, R.; Jain, S.; Purushottam, M.; Viswanath, B.; Sud, R.
10.1101/2023.07.15.549177 — neuroscience — Posted on 2023-07-18
2046 Brain aromatase dynamics reflect parental experience and behaviour in male mice
Duarte-Guterman, P.; Skandalis, D. A.; Merkl, A.; Geissler, D. B.; Ehret, G.
10.1101/2023.07.15.549144 — neuroscience — Posted on 2023-07-18
2048 Reaching the tumor: mobility of polymeric micelles inside an in vitro tumor-on-a-chip model with dual ECM
Olea, A. R.; Jurado, A.; Slor, G.; Tevet, S.; Pujals, S.; De La Rosa, V. R.; Hoogenboom, R.; Amir, R. J.; Albertazzi, L.
10.1101/2023.07.14.548885 — bioengineering — Posted on 2023-07-18
2049 Rapid mode switching facilitates the growth of Trichodesmium: A model analysis.
Gao, M.; Andrews, J.; Armin, G.; Chakraborty, S.; Zehr, J. P.; Inomura, K.
10.1101/2023.07.14.549029 — ecology — Posted on 2023-07-18
2053 Differential laboratory passaging of SARS-CoV-2 viral stocks impacts the in vitro assessment of neutralizing antibodies
Avila-Herrera, A.; Kimbrel, J.; Manuel Marti, J.; Thissen, J.; Saada, E.; Weisenberger, T.; Arrildt, K.; Segelke, B.; Allen, J.; Zemla, A. T.; Borucki, M. K.
10.1101/2023.07.14.549044 — molecular biology — Posted on 2023-07-18
2055 Hypnotic treatment reverses NREM sleep disruption and EEG desynchronization in a mouse model of Fragile X syndrome to rescue memory consolidation deficits.
Martinez, J. D.; Wilson, L. G.; Brancaleone, W.; Peterson, K.; Popke, D. S.; Caicedo Garzon, V.; Perez Tremble, R.; Donnelly, M. J.; Mendez Ortega, S.; Torres, D.; Shaver, J.; Clawson, B. C.; Jiang, S.; Yang, Z.; Aton, S.
10.1101/2023.07.14.549070 — neuroscience — Posted on 2023-07-18
2056 EasyEyes - Accurate fixation for online vision testing of crowding and beyond
Kurzawski, J. W.; Pombo, M.; Burchell, A.; Hanning, N. M.; Liao, S.; Majaj, N. J.; Pelli, D.
10.1101/2023.07.14.549019 — neuroscience — Posted on 2023-07-18
2057 Towards the automated detection of interictal epileptiform discharges with magnetoencephalography
Fernandez-Martin, R.; Feys, O.; Juvene, E.; Aeby, A.; Urbain, C.; De Tiege, X.; Wens, V.
10.1101/2023.07.14.548995 — neuroscience — Posted on 2023-07-18
2058 Pain reflects the informational value of nociceptive inputs.
Coll, M.-P.; Walden, Z.; Bourgoin, P.-A.; Taylor, V.; Rainville, P.; Robert, M.; Nguyen, D. K.; Jolicoeur, P.; Roy, M.
10.1101/2023.07.14.549006 — neuroscience — Posted on 2023-07-18
2062 COVFlow: performing virus phylodynamics analyses from selected SARS-CoV-2 genome sequences
Danesh, G.; Boennec, C.; Verdurme, L.; Roussel, M.; Trombert, S.; Visseaux, B.; Haim-Boukobza, S.; Alizon, S.
10.1101/2022.06.17.496544 — bioinformatics — Posted on 2023-07-18
2071 Unmasking Crucial Residues in Adipose Triglyceride Lipase (ATGL) for Co-Activation with Comparative Gene Identification-58 (CGI-58)
Kulminskaya, N.; Rodriguez Gamez, C. F.; Hofer, P.; Cerk, I. K.; Dubey, N.; Viertlmayr, R.; Sagmeister, T.; Pavkov-Keller, T.; Zechner, R.; Oberer, M.
10.1101/2023.06.26.546551 — biochemistry — Posted on 2023-07-18
2073 Rational Prediction of PROTAC-compatible Protein-Protein Interfaces by Molecular Docking
Pereira, G.; Garcia, B. J.; Pellarin, R.; Launay, G.; Wu, S.; Martin, J.; de Souza, P. C. T.
10.1101/2023.02.16.528819 — bioinformatics — Posted on 2023-07-18
2074 Do orexin/hypocretin neurons track sensory, cognitive, or motor information?
Bracey, E.; Aravind, A.; Grujic, N.; Peleg-Raibstein, D.; Burdakov, D.
10.1101/2022.04.13.488195 — neuroscience — Posted on 2023-07-18
2075 Root barrier surveillance mechanisms convey soil nitrogen status to shoots
Shen, D.; Wippel, K.; Remmel, S.; Zhang, P.; Kuertoes, N.; Neumann, U.; Kopriva, S.; Andersen, T. G.
10.1101/2023.04.19.537470 — plant biology — Posted on 2023-07-18
2077 One gene - two proteins: The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration.
Petragnano, F.; Fasciani, I.; Wang, Z.; Edwards, R.; Telugu, N.; Pietrantoni, I.; Zabel, U.; Zauber, H.; Grieben, M.; Terzenidou, M. E.; Di Gregorio, J.; Pellegrini, C.; Santini, S.; Taddei, A. R.; Poehl, B.; Aringhieri, S.; Carli, M.; Aloisi, G.; Marampon, F.; Charlesworth, E.; Roman, A.; Diecke, S.; Flati, V.; Giorgi, F.; Scarselli, M.; Tobin, A. B.; Amicarelli, F.; Tokatlidis, K.; Rossi, M.; Lohse, M. J.; Annibale, P.; Maggio, R.
10.1101/2021.04.13.438299 — cell biology — Posted on 2023-07-18
2078 Introducing PandaNovo for practical large-scale de novo peptide sequencing
Yang, T.; Ling, T.; Sun, B.; Liang, Z.; Xu, F.; Huang, X.; Xie, L.; He, Y.; Li, L.; He, F.; Wang, Y.; Chang, C.
10.1101/2023.07.15.549133 — bioinformatics — Posted on 2023-07-18
2080 Loss of type VI secretion systems in multi-drug resistant Escherichia coli clones
Cummins, E.; Moran, R.; Snaith, A.; Hall, R.; Connor, C.; Dunn, S.; McNally, A.
10.1101/2023.03.28.534550 — microbiology — Posted on 2023-07-18
2081 Three components of human brain gene expression reflect normative developmental programmes with specific links to neurodevelopmental disorders
Dear, R.; Wagstyl, K.; Seidlitz, J.; Markello, R. D.; Arnatkeviciute, A.; Anderson, K. M.; Bethlehem, R. A. I.; Lifespan Brain Chart Consortium, ; Raznahan, A.; Bullmore, E. T.; Vertes, P.
10.1101/2022.10.05.510582 — neuroscience — Posted on 2023-07-18
2082 The Cousa objective: a long working distance air objective for multiphoton imaging in vivo
Yu, C.-H.; Yu, Y.; Adsit, L. M.; Chang, J. T.; Barchini, J.; Moberly, A. H.; Benisty, H.; Kim, J.; Young, B. K.; Heng, K.; Farinella, D. M.; Leikvoll, A.; Pavan, R.; Vistein, R.; Nanfito, B. R.; Hildebrand, D. G. C.; Otero-Coronel, S.; Vaziri, A.; Goldberg, J. L.; Ricci, A. J.; Fitzpatrick, D.; Cardin, J. A.; Higley, M.; Smith, G. B.; Kara, P.; Nielsen, K. J.; Smith, I. T.; Smith, S. L.
10.1101/2022.11.06.515343 — neuroscience — Posted on 2023-07-18
2083 Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting
Wei, J.; Lotfy, P.; Faizi, K.; Baungaard, S.; Gibson, E.; Wang, E.; Slabodkin, H.; Kinnaman, E.; Chandrasekaran, S.; Kitano, H.; Durrant, M. G.; Duffy, C. V.; Hsu, P. D.; Konermann, S.
10.1101/2021.09.14.460134 — bioengineering — Posted on 2023-07-18
2089 Anxious about rejection, avoidant of neglect: Infant marmosets tune their attachment based on individual caregiver's parenting style
Yano-Nashimoto, S.; Truzzi, A.; Shinozuka, K.; Murayama, A.; Kurachi, T.; Moriya-Ito, K.; Tokuno, H.; Miyazawa, E.; Esposito, G.; Okano, H.; Nakamura, K.; Saito, A.; Kuroda, K. O.
10.1101/2023.05.18.541258 — animal behavior and cognition — Posted on 2023-07-17
2092 BAF chromatin complexes do not mediate GLI transcriptional repression of Hedgehog target genes
Ramachandran, J.; Chen, W.; Lex, R. K.; Windsor, K.; Lee, H.; Wang, T.; Zhou, W.; Ji, H.; Vokes, S. A.
10.1101/2023.02.03.527038 — developmental biology — Posted on 2023-07-17
2096 Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes
Brandt, P. D.; Whittington, D.; Wood, K. D.; Holmquist, C. E.; Nogueira, A. T.; Gaines, C. H.; Brennwald, P. J.; Layton, R. L.
10.1101/2023.07.13.548912 — scientific communication and education — Posted on 2023-07-17
2098 Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway
Plugge, S. F.; Ma, H.; van der Vaart, J. Y.; Sprangers, J.; Morsink, F. H. M.; Xanthakis, D.; Jamieson, C.; Keijzer, A. R.; Margaritis, T.; Candelli, T.; Straver, R.; de Ridder, J.; Holstege, F. C. P.; de Leng, W. W. J.; Offerhaus, G. J. A.; Merenda, A.; Maurice, M. M.
10.1101/2023.07.17.548873 — cancer biology — Posted on 2023-07-17
2099 Identifying Membrane Protein-Lipid Interactions with Lipidomic Lipid Exchange-Mass Spectrometry
Zhang, G.; Odenkirk, M. T.; Janczak, C. M.; Lee, R.; Richardson, K.; Wang, Z.; Aspinwall, C. A.; Marty, M. T.
10.1101/2023.06.02.543293 — biophysics — Posted on 2023-07-17
2100 Assessment of three-dimensional RNA structure prediction in CASP15
Das, R.; Kretsch, R. C.; Simpkin, A. J.; Mulvaney, T.; Pham, P.; Rangan, R.; Bu, F.; Keegan, R.; Topf, M.; Rigden, D.; Miao, Z.; Westhof, E.
10.1101/2023.04.25.538330 — biophysics — Posted on 2023-07-17
2101 Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP
Callahan, M. D.; Hodul, M.; Carroll, E. C.; Ravalin, M.; Nadel, C. M.; de Silva, A. R.; Cupo, A. R.; McDermott, L. E.; Nix, J. C.; Page, R. C.; Kao, A. W.; Gestwicki, J. E.
10.1101/2023.07.17.549407 — biochemistry — Posted on 2023-07-17
2102 Evolutionary trajectories of secondary replicons in multipartite genomes
Dranenko, N. O.; Rodina, A. D.; Demenchuk, Y. V.; Gelfand, M. S.; Bochkareva, O. O.
10.1101/2023.04.09.536151 — genomics — Posted on 2023-07-17
2103 Robust chromatin state annotation
Foroozandeh Shahraki, M.; Farahbod, M.; Libbrecht, M. W.
10.1101/2023.07.15.549175 — genomics — Posted on 2023-07-17
2104 Distinct ossification trade-offs illuminate the shoulder girdle reconfiguration at the water-to-land transition.
Wei, J.; Wood, T. W. P.; Flaherty, K.; Enny, A.; Andrescavage, A.; Brazer, D.; Navon, D.; Stewart, T. A.; Cohen, H.; Shanabag, A.; Kuroda, S.; Braasch, I.; Nakamura, T.
10.1101/2023.07.17.547998 — evolutionary biology — Posted on 2023-07-17
2108 Complex epistatic interactions between ELF3, PRR9, and PRR7 regulates the circadian clock and plant physiology
Yuan, L.; Avello, P.; Zhu, Z.; Lock, S. C. L.; McCarthy, K.; Redmond, E. J.; Davis, A. M.; Song, Y.; Ezer, D.; Pitchford, J. W.; Quint, M.; Xie, Q.; Xu, X.; Davis, S. J.; Ronald, J.
10.1101/2023.07.17.547649 — plant biology — Posted on 2023-07-17
2110 Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth
Rashidfarrokhi, A.; Pillai, R.; Hao, Y.; Wu, W.; Karadal-Ferrena, B.; dimitriadoy, S. G.; Cross, M.; Yeaton, A. H.; Ming Huang, S.; Bhutkar, A. J.; Herrera, A.; Rajalingam, S.; Hayashi, M.; Huang, K.-l.; Bartnicki, E.; Zavitsanou, A.-M.; Wohlhieter, C.; Leboeuf, S. E.; Chen, T.; Loomis, C.; Mezzano, V.; Kulicke, R.; Davis, F. P.; Stransky, N.; Smolen, G. A.; Rudin, C. M.; Moreira, A. L.; Khanna, K. M.; Pass, H. I.; Wong, K.-K.; Koide, S.; Tsirigos, A.; Koralov, S. B.; Papagiannakopoulos, T.
10.1101/2023.07.15.549147 — cancer biology — Posted on 2023-07-17
2115 Exploration of DPP-IV inhibitory peptide design rules assisted by deep learning pipeline that identifies restriction enzyme cutting site
Guan, C.; Luo, J.; Li, S.; Tan, Z. L.; Wang, Y.; Chen, H.; Yamamoto, N.; Zhang, C.; Lu, Y.; Chen, J.; Xing, X.-H.
10.1101/2022.06.13.495896 — bioinformatics — Posted on 2023-07-17
2117 A monochromatically excitable green-red dual-fluorophore fusion incorporating a new large Stokes shift fluorescent protein
Ejike, J. O.; Sadoine, M.; Shen, Y.; Ishikawa, Y.; Sunal, E.; Hänsch, S.; Hamacher, A. B.; Frommer, W. B.; Wudick, M. M.; Campbell, R. E.; Kleist, T. J.
10.1101/2023.07.16.549156 — bioengineering — Posted on 2023-07-17
2120 Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours
Grenko, C.; Bonnycastle, L. L.; Taylor, H. J.; Yan, T.; Swift, A. J.; Robertson, C. C.; Narisu, N.; Erdos, M. R.; Collins, F. S.; Taylor, D. L.
10.1101/2023.06.06.543931 — genetics — Posted on 2023-07-17
2122 Human genetic adaptation related to cellular zinc homeostasis
Roca-Umbert, A.; Garcia-Calleja, J.; Vogel-Gonzalez, M.; Fierro-Villegas, A.; Ill-Raga, G.; Herrera-Fernandez, V.; Bosnjak, A.; Muntane, G.; Gutierrez, E.; Campelo, F.; Vicente, R.; Bosch, E.
10.1101/2022.06.29.498106 — evolutionary biology — Posted on 2023-07-17
2123 Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore
Rao, S.; Strong, L. M.; Ren, X.; Skulsuppaisarn, M.; Lazarou, M.; Hurley, J. H.; Hummer, G.
10.1101/2023.07.17.549391 — cell biology — Posted on 2023-07-17
2129 Persistent effects of intramammary ceftiofur treatment on the gut microbiome and antibiotic resistance in dairy cattle
Vasco, K. A.; Carbonell, S.; Sloup, R. E.; Bowcutt, B.; Colwell, R. R.; Graubics, K.; Erskine, R.; Norby, B.; Ruegg, P. L.; Zhang, L.; Manning, S. D.
10.1101/2023.07.17.549362 — microbiology — Posted on 2023-07-17
2131 Intranasal CRMP2-Ubc9 Inhibitor Regulates NaV1.7 to Alleviate Trigeminal Neuropathic Pain
Loya-Lopez, S. I.; Allen, H. N.; Duran, P.; Calderon-Rivera, A.; Gomez, K.; Kumar, U.; Shields, R.; Zeng, R.; Dwivedi, A.; Saurabh, S.; Korczeniewska, O. A.; Khanna, R.
10.1101/2023.07.16.549195 — neuroscience — Posted on 2023-07-17
2134 GRK specificity and beta gamma dependency determines a GPCR`s potential in biased agonism
Matthees, E. S.; Filor, J. C.; Jaiswal, N.; Reichel, M.; Youssef, N.; Drube, J.; Godbole, A.; Hoffmann, C.
10.1101/2023.07.14.548990 — pharmacology and toxicology — Posted on 2023-07-17
2135 Bidirectional interconversion between mutually exclusive tumorigenic and drug-tolerant melanoma cell phenotypes
Zhang, Y.; Belote, R. L.; Urquijo, M. A.; Hansen, M. M.; Hejna, M.; Moustafa, T. E.; Liu, T.; Lange, D.; Vand-Rajabpour, F.; Chang, M.; Lohman, B. K.; Stubben, C.; Zhang, X.; Weinberger, L. S.; VanBrocklin, M. W.; Grossman, D.; Lex, A.; Kulkarni, R.; Zangle, T. A.; Judson-Torres, R. L.
10.1101/2020.08.26.269126 — cancer biology — Posted on 2023-07-17
2137 Apis mellifera filamentous virus from a honey bee gut microbiome survey in Hungary
Toth, A. G.; Papp, M.; Bekesi, L.; Farkas, R.; Makrai, L.; Maroti, G.; Solymosi, N.
10.1101/2023.07.17.549372 — bioinformatics — Posted on 2023-07-17
2138 kmindex and ORA: indexing and real-time user-friendly queries in terabytes-sized complex genomic datasets
Lemane, T.; Lezzoche, N.; Lecubin, J.; Pelletier, E.; Lescot, M.; Chikhi, R.; Peterlongo, P.
10.1101/2023.05.31.543043 — bioinformatics — Posted on 2023-07-17
2140 PACT - Prediction of Amyloid Cross-interaction by Threading
Wojciechowski, J. W.; Szczurek, W.; Szulc, N.; Szefczyk, M.; Kotulska, M.
10.1101/2022.07.07.499150 — bioinformatics — Posted on 2023-07-17
2141 Simultaneous multi-site editing of individual genomes using retron arrays
Gonzalez-Delgado, A.; Lopez, S. C.; Rojas-Montero, M.; Fishman, C. B.; Shipman, S. L.
10.1101/2023.07.17.549397 — bioengineering — Posted on 2023-07-17
2142 tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
Strassler, S. E.; Bowles, I. E.; Krishnamohan, A.; Kim, H.; Kuiper, E. G.; Hancock, C. J.; Comstock, L.; Jackman, J. E.; Conn, G. L.
10.1101/2023.02.01.526536 — biochemistry — Posted on 2023-07-17
2143 Conformational dynamics underlying Atypical Chemokine Receptor 3 activation
Otun, O.; Aljamous, C.; Del Nero, E.; Arimont-Segura, M.; Bosma, R.; Zarzycka, B.; Girbau, T.; Leyrat, C.; de Graaf, C.; Leurs, R.; Durroux, T.; Granier, S.; Cong, X.; BECHARA, C.
10.1101/2023.07.17.549382 — biochemistry — Posted on 2023-07-17
2147 Evaluation of noninvasive biospecimens for transcriptome studies
Martorella, M.; Kasela, S.; Garcia-Flores, R.; Gokden, A.; Castel, S. E.; Lappalainen, T.
10.1101/2022.09.06.506813 — genomics — Posted on 2023-07-17
2149 Broad functional profiling of fission yeast proteins using phenomics and machine learning
Rodriguez-Lopez, M.; Bordin, N.; Lees, J.; Scholes, H.; Hassan, S.; Saintain, Q.; Kamrad, S.; Orengo, C.; Bähler, J.
10.1101/2023.04.05.535764 — genetics — Posted on 2023-07-17
2151 Global determinants of insect mitochondrial genetic diversity
French, C. M.; Bertola, L. D.; Carnaval, A. C.; Economo, E. P.; Kass, J. M.; Lohman, D. J.; Marske, K. A.; Meier, R.; Overcast, I.; Rominger, A. J.; Staniczenko, P.; Hickerson, M. J.
10.1101/2022.02.09.479762 — evolutionary biology — Posted on 2023-07-17
2158 Phylogenetic diversity and functional potential of large and cell-associated viruses in the Bay of Bengal
Minch, B.; Akter, S.; Weinheimer, A.; Rahman, M. S.; Parvez, M. A. K.; Rahman, S. R.; Ahmed, M. F.; Moniruzzaman, M.
10.1101/2023.07.17.548743 — microbiology — Posted on 2023-07-17
2160 Understanding off-target growth defects introduced to influenza A virus by synonymous recoding
Sharp, C. P.; Thompson, E. H.; Tesla, B.; Kurian, D.; Simmonds, P.; Digard, P.; Gaunt, E. R.
10.1101/2023.07.17.549395 — microbiology — Posted on 2023-07-17
2162 SIRT-1 is required for release of enveloped picornaviruses
Jassey, A.; Logue, J.; Weston, S.; Wagner, M. A.; Galitska, G.; Miller, K. A.; Frieman, M. B.; Jackson, W. T.
10.1101/2022.08.12.503821 — microbiology — Posted on 2023-07-17
2163 Pre-existing interferon gamma conditions the lung to mediate early control of SARS-CoV-2
Hilligan, K. L.; Namasivayam, S.; Clancy, C. S.; Baker, P. J.; Old, S. I.; Peluf, V.; Amaral, E. P.; Oland, S. D.; O'Mard, D.; Laux, J.; Cohen, M.; Garza, N. L.; Lafont, B.; Johnson, R. F.; Feng, C. G.; Jankovic, D.; Lamiable, O.; Mayer-Barber, K. D.; Sher, A.
10.1101/2023.07.15.549135 — immunology — Posted on 2023-07-17
2165 From Asymptomatic to Symptomatic: Multiomics profiling of the temporal response of grapevine viral-mixed infection
Lamine Fall, M.; Poursalavati, A.; Sidibe, A.; Xu, D.; Lemoyne, P.; Silva Martins, G.; Jalali Javaran, V.; Moffett, P.; Odile, C.
10.1101/2023.07.17.549167 — plant biology — Posted on 2023-07-17
2168 sNucConv: A bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition of human subcutaneous and visceral adipose tissues
Sorek, G.; Haim, Y.; Chalifa-Caspi, V.; Lazarescu, O.; Ziv, M.; Hagemann, T.; Nono Nankam, P.; Bluher, M.; Liberty, I. F.; Dukhno, O.; Kukeev, I.; Yeger-Lotem, E.; Rudich, A.; Levin, L.
10.1101/2023.07.16.549187 — bioinformatics — Posted on 2023-07-17
2171 A single cell atlas of sexual development in Plasmodium falciparum
Dogga, S. K.; Rop, J. C.; Cudini, J.; Farr, E.; Dara, A.; Ouologuem, D.; Djimde, A. A.; Talman, A. M.; Lawniczak, M. K. N.
10.1101/2023.07.16.547819 — genomics — Posted on 2023-07-17
2173 Multi-monoubiquitination controls VASP-mediated actin dynamics
McCormick, L. E.; Suarez, C.; Herring, L. E.; Cannon, K. S.; Kovar, D. R.; Brown, N. G.; Gupton, S. L.
10.1101/2023.07.16.549237 — cell biology — Posted on 2023-07-17
2174 Megakaryocyte infection by SARS-CoV-2 drives the formation of pathogenic afucosylated IgG antibodies in mice
Mabrouk, M.; Jalali, F.; Zaid, N.; Naya, A.; Khyatti, M.; Khalki, L.; Guessous, F.; Zaid, Y.
10.1101/2023.07.14.549113 — immunology — Posted on 2023-07-17
2176 PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons
Milioto, C.; Carcole, M.; Giblin, A.; Coneys, R.; Attrebi, O.; Ahmed, M.; Harris, S. S.; Lee, B. I.; Yang, M.; Nirujogi, R. S.; Biggs, D.; Salomonsson, S.; Zanovello, M.; De Oliveira, P.; Katona, E.; Glaria, I.; Mikheenko, A.; Geary, B.; Udine, E.; Vaizoglu, D.; Rademakers, R.; van Blitterswijk, M.; Devoy, A.; Hong, S.; Partridge, L.; Fratta, P.; Alessi, D.; Davies, B.; Busche, M. A.; Greensmith, L.; Fisher, E. M.; Isaacs, A. M.
10.1101/2023.07.17.549331 — neuroscience — Posted on 2023-07-17
2178 Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells
Qian, C.; Xin, Y.; Qi, C.; Wang, H.; Dong, B. C.; Zack, D.; Blackshaw, S.; Hattar, S.; Zhou, F.; Qian, J.
10.1101/2023.07.14.549118 — neuroscience — Posted on 2023-07-17
2179 Voltage tunes mGlu5 receptor function, impacting synaptic transmission
Boutonnet, M.; Carpena, C.; Bouquier, N.; Chastagnier, Y.; Font-Ingles, J.; Moutin, E.; Tricoire, L.; Chemin, J.; Perroy, J.
10.1101/2023.07.17.549279 — neuroscience — Posted on 2023-07-17
2184 Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits
Bian, C.; Demirer, G. S.; Oz, M. T.; Cai, Y.; Witham, S.; Mason, G. A.; Shen, R.; Ahn, J.; Gaudinier, A.; Brady, S.; Patron, N.
10.1101/2023.07.17.549299 — plant biology — Posted on 2023-07-17
2186 A data standard for the reuse and reproducibility of any stable isotope probing-derived nucleic acid sequence (MISIP)
Simpson, A. M. R.; Wood Charlson, E. M.; Smith, M.; Beilsmith, K.; Koch, B.; Walls, R. L.; Wilhelm, R. C.
10.1101/2023.07.13.548835 — bioinformatics — Posted on 2023-07-17
2188 Systems Age: A single blood methylation test to quantify aging heterogeneity across 11 physiological systems
Sehgal, R.; Meer, M.; Shadyab, A. H.; Casanova, R.; Manson, J. E.; Bhatti, P.; Crimmins, E. M.; Assimes, T. L.; Whitsel, E. A.; Higgins-Chen, A. T.; Levine, M.
10.1101/2023.07.13.548904 — systems biology — Posted on 2023-07-17
2189 Performance of large scale pooled CRISPR screens is dependent on Cas9 expression levels
Fernandes Neto, J. M.; Jastrzebski, K.; Lieftink, C.; Krenning, L.; Dias, M.; Morris, B.; van der Ven, D.; Heimans, H.; Medema, R. H.; Bernards, R.; Beijersbergen, R. L.
10.1101/2021.07.13.452178 — genomics — Posted on 2023-07-17
2191 Deep spatial proteomic exploration of severe COVID-19-related pulmonary injury in post-mortem specimens
Mao, Y.; Chen, Y.; Li, Y.; Ma, L.; Wang, X.; Wang, Q.; He, A.; Liu, X.; Dong, T.; Gao, W.; Xu, Y.; Liu, L.; Ren, L.; Liu, Q.; Zhou, P.; Hu, B.; Zhou, Y.; Tian, R.; Shi, Z.-L.
10.1101/2023.07.14.548971 — systems biology — Posted on 2023-07-17
2196 Distinct Functional States of Neutrophils by Actin Disassembly and NF-kB/STAT3 Signaling
Wabnitz, G. H.; Heineken, N.; Schumacher, J.-C.; Exner, T.; Neuenfeldt, F.; Habicht, J.; Kahlich, F.; Platzer, H.; Merle, U.; Renkawitz, T.; Samstag, Y.; Grieshaber-Bouyer, R.; Autenrieth, S.
10.1101/2023.07.14.548975 — immunology — Posted on 2023-07-17
2198 The influence of inter-regional delays in generating large-scale brain networks of phase synchronization
Williams, N.; Ojanpera, A.; Siebenhuhner, F.; Toselli, B.; Palva, S.; Arnulfo, G.; Kaski, S.; Palva, J. M.
10.1101/2023.03.27.534336 — neuroscience — Posted on 2023-07-17
2199 Extended lifespan in female Drosophila melanogaster through late-life caloric restriction.
Li, M.; Macro, J.; Huggins, B. J.; Meadows, K.; Mishra, D.; Martin, D.; Rogina, B.
10.1101/2023.07.13.548896 — physiology — Posted on 2023-07-17
2200 CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival
Lier, S.; Lund, S. O.; Lipsa, A.; Frauenknecht, K. B. M.; Rein, I. D.; Jain, P.; Lang, A.; Lang, E.; Meyer, N.; Datta, A.; Anand, S.; Nesse, G.; Forstrom, R. J.; Klungland, A.; Rinholm, J. E.; Boe, S. O.; Anand, A.; Pollard, S. M.; Niclou, S. P.; Lerdrup, M.; Pandey, D. P.
10.1101/2023.07.14.548985 — cancer biology — Posted on 2023-07-17
2204 Tropical invertebrate community assembly processes are robust to a gradient of land use intensity
Granville, N. R.; Barclay, M. V. L.; Boyle, M. J. W.; Chung, A. Y. C.; Fayle, T. M.; Hah, H. E.; Hardwick, J. L.; Kinneen, L.; Kitching, R. L.; Maunsell, S. C.; Miller, J. A.; Sharp, A. C.; Stork, N. E.; Wai, L.; Yusah, K. M.; Ewers, R. M.
10.1101/2023.01.30.526177 — ecology — Posted on 2023-07-17
2205 Stand age diversity weakens forests sensitivity to climate change
Vangi, E.; Cioccolo, E.; Marano, G.; Dalmonech, D.; Bianchini, L.; Puchi, P.; Grieco, E.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2023-07-17
2207 Molecular quantitative trait loci in reproductive tissues impact male fertility in a large mammal
Mapel, X. M.; Kadri, N. K.; Leonard, A. S.; He, Q.; Lloret-Villas, A.; Bhati, M.; Hiltpold, M.; Pausch, H.
10.1101/2023.06.29.547066 — genomics — Posted on 2023-07-17
2208 Domestication in dry-cured meat Penicillium fungi: convergent specific phenotypes and horizontal gene transfers without strong genetic subdivision
Lo, Y.-C.; Bruxaux, J.; Rodriguez de la Vega, R. C.; O'Donnell, S.; Snirc, A.; Coton, M.; Le Piver, M.; Le Prieur, S.; Roueyre, D.; Dupont, J.; Houbraken, J.; Debuchy, R.; Ropars, J.; Giraud, T.; Branca, A.
10.1101/2022.03.25.485132 — evolutionary biology — Posted on 2023-07-17
2209 The transcription factor Zeb2 drives differentiation of age-associated B cells
Dai, D.; Gu, S.; Han, X.; Ding, H.; Jiang, Y.; Zhang, X.; Yao, C.; Hong, S.; Zhang, J.; Shen, Y.; Hou, G.; Qu, B.; Zhou, H.; Qin, Y.; He, Y.; Ma, J.; Yin, Z.; Ye, Z.; Qian, J.; Jiang, Q.; Wu, L.; Guo, Q.; Chen, S.; Huang, C.; Kottyan, L.; Weirauch, M. T.; Vinuesa, C. G.; Shen, N.
10.1101/2021.07.24.453633 — immunology — Posted on 2023-07-17
2210 A megaprotein brake for aging and insulin-mTOR signaling
Pandey, T.; Wang, B.; Wang, C.; Zu, J.; Deng, H.; Shen, K.; Vale, G.; McDonald, J. G.; Ma, D. K.
10.1101/2023.02.14.528431 — physiology — Posted on 2023-07-17
2211 Glycan-specific IgM is critical for human immunity to Staphylococcus aureus
Hendriks, A.; Kerkman, P. F.; Varkila, M. R.; Haitsma-Mulier, J. L.; Ali, S.; ten Doesschate, T.; van der Vaart, T. W.; de Haas, C. J. C.; Aerts, P. C.; Cremer, O. L.; Bonten, M. J.; Nizet, V.; Liu, G. Y.; Codee, J. D. C.; Rooijakkers, S. H.; van Strijp, J. A.; van Sorge, N. M.
10.1101/2023.07.14.548956 — microbiology — Posted on 2023-07-16
2212 Serpine1 negatively regulates Th1 cell responses in experimental autoimmune encephalomyelitis.
Akbar, I.; Tang, R.; Baillargeon, J.; Roy, A.-P.; Doss, P. M. I. A.; Zhu, C.; Kuchroo, V. K.; Rangachari, M.
10.1101/2023.07.13.548887 — immunology — Posted on 2023-07-16
2213 Absorption changes in Photosystem II in the Soret band region upon the formation of the chlorophyll cation radical +
Boussac, A.; Sugiura, M.; Nakamura, M.; Nagao, R.; Noguchi, T.; Viola, S.; Rutherford, A. W.; Selles, J.
10.1101/2022.05.12.491653 — biophysics — Posted on 2023-07-16
2215 Fully automated and integrated proteomics sample preparation platform for high-throughput drug target identification
Wu, Q.; Zheng, J.; Sui, X.; Fu, C.; Cui, X.; Liao, B.; Ji, H.; Luo, Y.; He, A.; Lu, X.; Tan, C. S. H.; Tian, R.
10.1101/2023.07.14.548974 — systems biology — Posted on 2023-07-16
2216 Basal expression of immune receptor genes requires low levels of the phytohormone salicylic acid
van Butselaar, T.; Silva, S.; Lapin, D.; Banales, I.; Tonn, S.; van Schie, C.; Van den Ackerveken, G.
10.1101/2023.07.14.548351 — plant biology — Posted on 2023-07-16
2217 Ischaemic Preconditioning attenuates Chronic Renal Damage following Ischaemia Reperfusion Injury
Brown, C. V. M.; Pino-Chavez, G.; Zaidi, A.; Grigorieva, I.; Woods, E.; Steadman, R.; Chavez, R.; Meran, S.; Khalid, U.
10.1101/2023.07.13.548869 — pathology — Posted on 2023-07-16
2221 Neural stimulation hardware for the selective intrafascicular modulation of the vagus nerve
Strauss, I.; Agnesi, F.; Zinno, C.; Giannotti, A.; Dushpanova, A.; Casieri, V.; Terlizzi, D.; Bernini, F.; Gabisonia, K.; Wu, Y.; Jiang, D.; Paggi, V.; Lacour, S.; Recchia, F. A.; Demosthenous, A.; Lionetti, V.; Micera, S.
10.1101/2023.07.14.548991 — bioengineering — Posted on 2023-07-16
2222 New germline Cas9 promoters show improved performance for homing gene drive
Du, J.; Chen, W.; Jia, X.; Xu, X.; Yang, E.; Zhou, R.; Zhang, Y.; Metzloff, M.; Messer, P. W.; Champer, J.
10.1101/2023.07.16.549205 — genetics — Posted on 2023-07-16
2223 Divergent recovery trajectories in reef-building corals following a decade of successive marine heatwaves
Brown, K. T.; Lenz, E. A.; Glass, B. H.; Kruse, E.; McClintock, R.; Drury, C.; Nelson, C. E.; Putnam, H. M.; Barott, K. L.
10.1101/2023.07.16.549193 — ecology — Posted on 2023-07-16
2226 A novel polycistronic method tailored for engineering split GECIs
Olszakier, S.; Hussein, W.; Heinrich, R.; Andreyanov, M.; Otor, Y.; Schiller, J.; Kellner, S.; Berlin, S.
10.1101/2023.07.16.549202 — neuroscience — Posted on 2023-07-16
2227 Impact of High Fat Diet and Sex in a Rabbit Model of Carpal Tunnel Syndrome
Kuroiwa, T.; Lui, H.; Nakagawa, K.; Iida, N.; Desrochers, C.; Wan, R.; Adam, E.; Larson, D.; Amadio, P. C.; Gingery, A.
10.1101/2023.07.15.549152 — physiology — Posted on 2023-07-16
2228 p53 amyloid pathology with cancer grades and p53 mutations
Sengupta, S.; Singh, N.; Paul, A.; Datta, D.; Chatterjee, D.; Mukherjee, S.; Gadhe, L.; Devi, J.; M, Y.; Jolly, M. K.; Maji, S. K.
10.1101/2023.07.14.547625 — cancer biology — Posted on 2023-07-16
2232 RNA Strain-Match: A tool for matching single-nucleus, single-cell, or bulk RNA-sequencing alignment data to its corresponding genotype
Willcox, J. A. L.; Telpoukhovskaia, M. A.; Hadad, N.; Boas, S. M.; Dunn, A.; Saul, M. C.; Ashbrook, D. G.; Williams, R. W.; O'Connell, K. M. S.; Kaczorowski, C. C.
10.1101/2023.07.14.548847 — bioinformatics — Posted on 2023-07-16
2236 Cohesin forms fountains at active enhancers in C. elegans
Isiaka, B.; Semple, J.; Haemmerli, A.; Thapliyal, S.; Stojanovski, K.; Das, M.; Gilbert, N.; Glauser, D. A.; Towbin, B. D.; Jost, D.; Meister, P.
10.1101/2023.07.14.549011 — genomics — Posted on 2023-07-16
2237 Using UAV-based temporal spectral indices to dissect changes in the stay green trait in wheat
Rui, Y.; feng, C. x.; jia, L.; qi, N. R.; liang, Z. C.; Meng, Y.; Huang, Y.; zhe, L. X.; Zheng, W.-J.; fa, W. C.; ting, W. T.; feng, S. B.; Kang, Z.; Zeng, Q.; jun, H. D.; Wu, J.
10.1101/2023.07.14.549080 — genetics — Posted on 2023-07-16
2238 Virus replication in the honey bee parasite, Varroa destructor
Damayo, J. E.; McKee, R. C.; Buchmann, G.; Norton, A. M.; Ashe, A.; Remnant, E. J.
10.1101/2023.07.16.549232 — genetics — Posted on 2023-07-16
2239 Evolution of compound eye morphology underlies differences in vision between closely related Drosophila species
Buffry, A. D.; Currea, J. P.; Franke, F. A.; Palavalli-Nettimi, R.; Bodey, A. P.; Rau, C.; Samadi, N.; Gstöhl, S. J.; Schlepütz, C. M.; McGregor, A. P.; Sumner-Rooney, L.; Theobald, J.; Kittelmann, M.
10.1101/2023.07.16.549164 — evolutionary biology — Posted on 2023-07-16
2240 Maresin-2 Fine-tunes ULK1 O-GlcNAcylation to Improve Post Myocardial Infarction Remodeling
Zhang, J.; Li, C.; Wei, Y.; Jiang, S.; Wu, X.; Zhou, Q.; Yang, S.; Hu, H.; He, H.; Kong, B.; Shuai, W.
10.1101/2023.07.16.549182 — molecular biology — Posted on 2023-07-16
2249 Neural tube organoids self-organise floorplate through BMP-mediated cluster competition
Krammer, T.; Stuart, H. T.; Gromberg, E.; Ishihara, K.; Melchionda, M.; Wang, J.; Costantini, E.; Lehr, S.; Cislo, D.; Arbanas, L.; Hoermann, A.; Neumueller, R. A.; Elvassore, N.; Siggia, E.; Briscoe, J.; Kicheva, A.; Tanaka, E. M.
10.1101/2023.06.25.546258 — developmental biology — Posted on 2023-07-16
2251 CLIPB4 is a central node in the protease network that regulates humoral immunity in Anopheles gambiae mosquitoes
Zhang, X.; Zhang, S.; Kuang, J.; Sellens, K. A.; Morejon, B.; Saab, S. A.; Metto, E. M.; Li, M.; Osta, M.; An, C.; Culbertson, C. T.; Scoglio, C. M.; Michel, K.
10.1101/2023.07.07.545904 — immunology — Posted on 2023-07-16
2255 Distinct senescence mechanisms restrain progression of dysplastic nevi
Lorbeer, F. K.; Rieser, G.; Goel, A.; Wang, M.; Oh, A.; Yeh, I.; Bastian, B. C.; Hockemeyer, D.
10.1101/2023.07.14.548818 — cancer biology — Posted on 2023-07-16
2257 A 3D microtumour system that faithfully represents ovarian cancer minimal residual disease
Yang, X.; Artibani, M.; Jin, Y.; Aggarwal, A.; Zhang, Y.; Munoz-Galvan, S.; Mikhailova, E.; Rai, L.; Mukherjee, N.; Krishna Kumar, R.; Albukhari, A.; Zhou, L.; Ahmed, A.; Bayley, H.
10.1101/2023.07.15.549155 — cancer biology — Posted on 2023-07-16
2258 Myosin-5 varies its steps along the irregular F-actin track
Fineberg, A.; Takagi, Y.; Thirumurugan, K.; Andrecka, J.; Billington, N.; Young, G.; Cole, D.; Burgess, S. A.; Curd, A. P.; Hammer, J. A.; Sellers, J. R.; Kukura, P.; Knight, P. J.
10.1101/2023.07.16.549178 — biophysics — Posted on 2023-07-16
2259 Ubiquitination-mediated Golgi-to-endosome sorting determines the poison-antidote duality of wtf meiotic drivers
Zheng, J.-X.; Du, T.-Y.; Shao, G.-C.; Ma, Z.-H.; Jiang, Z.-D.; Hu, W.; Suo, F.; He, W.; Dong, M.-Q.; Du, L.-L.
10.1101/2023.07.15.549172 — cell biology — Posted on 2023-07-16
2262 Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization
Jahn, D.; Knapstein, P. R.; Otto, E.; Köhli, P.; Sevecke, J.; Graef, F.; Graffmann, C.; Fuchs, M.; Jiang, S.; Rickert, M.; Erdmann, C.; Appelt, J.; Revend, L.; Küttner, Q.; Witte, J.; Rahmani, A.; Duda, G.; Xie, W.; Donat, A.; Schinke, T.; Ivanov, A.; Ngokingha Tchouto, M.; Beule, D.; Frosch, K.-H.; Baranowsky, A.; Tsitsilonis, S.; Keller, J.
10.1101/2023.07.14.548550 — cell biology — Posted on 2023-07-16
2265 Refrigerated storage and cryopreservation of hormone induced sperm in a threatened frog
Upton, R.; Calatayud, N. E.; Clulow, S.; Brett, D.; Burton, A. L.; Colyvas, K.; Mahony, M.; Clulow, J.
10.1101/2023.07.15.548973 — cell biology — Posted on 2023-07-16
2268 Introducing PandaNovo for practical large-scale de novo peptide sequencing
Yang, T.; Ling, T.; Sun, B.; Liang, Z.; Xu, F.; Huang, X.; Xie, L.; He, Y.; Li, L.; He, F.; Wang, Y.; Chang, C.
10.1101/2023.07.15.549133 — bioinformatics — Posted on 2023-07-16
2269 Fear and foraging opportunities interact with temperature and seasonality to drive diversity in fish life histories
Kindsvater, H. K.; Juan Jorda, M. J.; Dulvy, N. K.; Horswill, C.; Matthiopoulos, J.; Mangel, M.
10.1101/2022.08.20.504655 — ecology — Posted on 2023-07-16
2270 Variational Log-Gaussian Point-Process Methods for Grid Cells
Rule, M. E.; Vayalambrone, P. C.; Krstulovic, M.; Bauza, M.; Krupic, J.; O'Leary, T.
10.1101/2023.03.18.533177 — neuroscience — Posted on 2023-07-16
2274 Two successive oligomeric Munc13 assemblies scaffold vesicle docking and SNARE assembly to support neurotransmitter release
Bera, M.; Grushin, K.; Kalyana Sundaram, V.; Shahanoor, Z.; Chatterjee, A.; Radhakrishnan, A.; Lee, S.; Padmanarayana, M.; Coleman, J.; Pincet, F.; Rothman, J. E.; Dittman, J. S.
10.1101/2023.07.14.549017 — neuroscience — Posted on 2023-07-16
2275 Amyloid β accelerates age-related proteome-wide protein insolubility.
Anderton, E.; Chamoli, M.; Bhaumik, D.; King, C. D.; Xie, X.; Foulger, A.; Andersen, J.; Schilling, B.; Lithgow, G.
10.1101/2023.07.13.548937 — systems biology — Posted on 2023-07-16
2277 Strong Positive Selection Biases Identity-By-Descent-Based Inferences of Recent Demography and Population Structure in Plasmodium falciparum
Guo, B.; Borda, V.; Laboulaye, R.; Spring, M. D.; Wojnarski, M.; Vesely, B. A.; Silva, J. C.; Waters, N. C.; O'Connor, T. D.; Takala-Harrison, S.
10.1101/2023.07.14.549114 — evolutionary biology — Posted on 2023-07-15
2278 The Biogenesis of Bacterial PHB Granules
de Koning, E. A.; Panjalingam, M.; Tran, J.; Eckhart, M. R.; Dahlberg, P. D.; Shapiro, L.
10.1101/2023.07.06.548030 — molecular biology — Posted on 2023-07-15
2279 Phytohemagglutinin-Activated CAR-T Cells: Prolonged Persistence and Enhanced Anti-Tumor Response in CD19-Specific Acute Lymphoblastic Leukemia
Sert, B.; Gulden, G.; Teymur, T.; Ay, Y.; Turan, R. D.; Unaldi, O. M.; Guzenge, E.; Erdil, H. E.; Isik, S.; Oz, P.; Bozkurt, I.; Arpaci, T.; Kamali, O.; Ovali, E.; Tarhan, N.; Tastan, C.
10.1101/2023.07.15.547808 — immunology — Posted on 2023-07-15
2280 NGFR regulates germinal center B-cell activation and negative selection
Hernandez-Barranco, A.; S. Mazariegos, M.; Santos, V.; Caleiras, E.; Nogues, L.; Mourcin, F.; Leonard, S.; Oblet, C.; Genebrier, S.; Rossille, D.; Benguria, A.; Vazquez, E.; Dopazo, A.; Efeyan, A.; Ortega-Molina, A.; Cogne, M.; Tarte, K.; Peinado, H.
10.1101/2023.07.14.548960 — immunology — Posted on 2023-07-15
2281 Single-cell and spatial multi-omics identify innate and stromal modules targeted by anti-integrin therapy in ulcerative colitis.
Mennillo, E.; Kim, Y. J.; Rusu, I.; Lee, G.; Dorman, L. C.; Bernard-Vazquez, F.; Bain, J. L.; Patel, R.; Andersen, C.; Rao, A.; Tamaki, S.; Tsui, J.; Shen, A.; Naser, M.; Eckalbar, W.; Cho, S.-j.; Beck, K.; El-Nachef, N.; Lewin, S.; Selvig, D. R.; Terdiman, J. P.; Mahadevan, U.; Oh, D.; Fragiadakis, G. K.; Pisco, A.; Combes, A.; Kattah, M. G.
10.1101/2023.01.21.525036 — immunology — Posted on 2023-07-15
2285 Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection
Aiyer, S.; Baldwin, P. R.; Tan, S. M.; Shan, Z.; Oh, J.; Mehrani, A.; Bowman, M. E.; Louie, G.; Passos, D. O.; Đorđevic-Marquardt, S.; Mietzsch, M.; Hull, J. A.; Hoshika, S.; Barad, B. A.; Grotjahn, D.; McKenna, R.; Agbandje-Mckenna, M.; Benner, S. A.; Noel, J. P.; Wang, D.; Tan, Y. Z.; Lyumkis, D.
10.1101/2023.07.14.548955 — biophysics — Posted on 2023-07-15
2287 Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogens
Hall, T. J.; McHugo, G. P.; Mullen, M. P.; Ward, J. A.; Killick, K. E.; Browne, J. A.; Gordon, S. V.; MacHugh, D. E.
10.1101/2023.07.14.549042 — genomics — Posted on 2023-07-15
2288 Reduction of ribosomal expansion segments in yeast species of the Magnusiomyces/Saprochaete clade
Brazdovic, F.; Brejova, B.; Sivakova, B.; Barath, P.; Vinar, T.; Tomaska, L.; Nosek, J.
10.1101/2023.07.14.548829 — genomics — Posted on 2023-07-15
2293 A CRISPRi-based genetic resource to study essential Staphylococcus aureus genes
Reed, P.; Sorg, M.; Alwardt, D.; Serra, L.; Veiga, H.; Schaeper, S.; Pinho, M. G.
10.1101/2022.10.31.514627 — microbiology — Posted on 2023-07-15
2295 The metabolic role of vitamin D in children's neurodevelopment: a network study
De Marzio, M.; Lasky-Su, J.; Chu, S. H.; Prince, N.; Litonjua, A. A.; Weiss, S. T.; Kelly, R. S.; Glass, K. R.
10.1101/2023.06.23.546277 — systems biology — Posted on 2023-07-15
2297 Internet-connected cortical organoids for project-based stem cell and neuroscience education
Elliott, M. A. T.; Schweiger, H. E.; Robbins, A.; Vera-Choqqueccota, S.; Ehrlich, D.; Hernandez, S.; Voitiuk, K.; Geng, J.; Sevetson, J. L.; Rosen, Y. M.; Teodorescu, M.; Wagner, N. O.; Haussler, D.; Mostajo-Radji, M. A.
10.1101/2023.07.13.546418 — scientific communication and education — Posted on 2023-07-15
2303 Tyk2-mediated signaling promotes the development of autoreactive CD8+ CTLs and autoimmune type 1 diabetes
Mine, K.; Nagafuchi, S.; Akazawa, S.; Abiru, N.; Mori, H.; Kurisaki, H.; Yoshikai, Y.; Takahashi, H.; Anzai, K.
10.1101/2023.07.14.548984 — immunology — Posted on 2023-07-15
2304 Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin
Reich, M.; Simon, M. J.; Polke, B.; Werner, G.; Schrader, C.; Paris, I.; Robinson, S.; Davis, S. S.; Lunkes de Melo, G.; Schlaphoff, L.; Spieth, L.; Berghoff, S.; Logan, T.; Nuscher, B.; Buschmann, K.; Edbauer, D.; Simons, M.; Suh, J.; Sandmann, T.; Kariolis, M. S.; DeVos, S. L.; Lewcock, J. W.; Paquet, D.; Capell, A.; Di Paolo, G.; Haass, C.
10.1101/2023.07.14.549089 — neuroscience — Posted on 2023-07-15
2305 Totally tubular: ASO-mediated knock-down of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages
Wallings, R.; Mark, J.; Staley, H.; Gillett, D.; Neighbarger, N.; hirst, w.; Kordasiewicz, H.; Tansey, M. G.
10.1101/2023.07.14.549028 — neuroscience — Posted on 2023-07-15
2306 Neurofeedback training can modulate task-relevant memory replay in rats
Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Desse, S.; Frank, L. M.
10.1101/2022.10.13.512183 — neuroscience — Posted on 2023-07-15
2307 Tessellation Of Artificial Touch Via Microstimulation Of Human Somatosensory Cortex
Greenspon, C. M.; Shelchkova, N. D.; Valle, G.; Hobbs, T.; Berger-Wolf, E. I.; Hutchison, B. C.; Dogruoz, E.; Verbarschott, C.; Callier, T.; Sobinov, A.; Okorokova, E. V.; Jordan, P. M.; Prasad, D.; He, Q.; Liu, F.; Kirsch, R. F.; Miller, J. P.; Lee, R. C.; Satzer, D.; Gonzalez-Martinez, J.; Warnke, P.; Miller, L. E.; Boninger, M. L.; Ajiboye, B. B.; Graczyk, E. L.; Downey, J. E.; Collinger, J.; Hatsopoulos, N.; Gaunt, R.; Bensmaia, S. J.
10.1101/2023.06.23.545425 — neuroscience — Posted on 2023-07-15
2308 Stand age diversity weakens forests sensitivity to climate change
Vangi, E.; Cioccolo, E.; Marano, G.; Dalmonech, D.; Bianchini, L.; Puchi, P.; Grieco, E.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2023-07-15
2311 A bespoke analytical workflow for the confident identification of sulfopeptides and their discrimination from phosphopeptides
Daly, L. A.; Byrne, D. P.; Perkins, S.; Brownridge, P. J.; McDonnell, E.; Jones, A. R.; Eyers, P. A.; Eyers, C. E.
10.1101/2023.07.15.549150 — biochemistry — Posted on 2023-07-15
2314 KDM4-dependent DNA breaks at active promoters facilitate +1 nucleosome eviction
Imre, L.; Nanasi, P.; Kokai, E.; Dombradi, V.; Szatmari, I.; Austin, C. A.; Szabo, G.
10.1101/2023.07.14.548993 — genetics — Posted on 2023-07-15
2316 Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation
Galitsyna, A.; Bykov, N.; Ulianov, S.; Veil, M.; Gao, M.; Perevoshchikova, K. Y.; Gelfand, M. S.; Razin, S. V.; Mirny, L. A.; Onichtchouk, D.
10.1101/2023.07.15.549120 — molecular biology — Posted on 2023-07-15
2317 Relationship Between Domain and Function of the Yeast RNase T2, Rny1p, Which Mediates rRNA Degradation upon Starvation
Minami, A.; Nishi, K.; Yamada, R.; Jinnai, G.; Shima, H.; Oishi, S.; Akagawa, H.; Aono, T.; Hidaka, M.; Masaki, H.; Kuzuyama, T.; Noda, Y.; Ogawa, T.
10.1101/2023.07.14.548783 — molecular biology — Posted on 2023-07-15
2319 Surrogate selection oversamples expanded T cell clonotypes
Yu, P.; Lian, Y.; Zuleger, C. L.; Albertini, R. J.; Albertini, M. R.; Newton, M. A.
10.1101/2023.07.13.548950 — immunology — Posted on 2023-07-15
2320 Origin and diversity of Capsella bursa-pastoris from the genomic point view.
Penin, A. A.; Kasianov, A. S.; Klepikova, A. V.; Omelchenko, D. O.; Makarenko, M. S.; Logacheva, M. D.
10.1101/2023.07.13.548917 — plant biology — Posted on 2023-07-15
2321 PEP-Patch: Electrostatics in Protein-Protein Recognition, Specificity and Antibody Developability
Waibl, F.; Pomarici, N. D.; Hoerschinger, V. J.; Loeffler, J. R.; Deane, C.; Georges, G.; Kettenberger, H.; Fernandez-Quintero, M. L.; Liedl, K. R.
10.1101/2023.07.14.547811 — biophysics — Posted on 2023-07-15
2323 Co-adaptation improves performance in a dynamic human-machine interface
Yamagami, M.; Madduri, M.; Chasnov, B. J.; Chou, A. H. Y.; Peterson, L. N.; Burden, S. A.
10.1101/2023.07.14.549053 — bioengineering — Posted on 2023-07-15
2325 GIS-FA: An approach to integrate thematic maps, factor-analytic and envirotyping for cultivar targeting
Araujo, M. S.; Chaves, S. F. S.; Dias, L. A. S.; Ferreira, F. M.; Pereira, G. R.; Bezerra, A. R. G.; Alves, R. S.; Heinemann, A. B.; Breseghello, F.; Carneiro, P. C. S.; Krause, M. D.; Costa-Neto, G.; Dias, K. O. G.
10.1101/2023.07.15.549137 — genetics — Posted on 2023-07-15
2329 Absence of SARS-CoV-2 in Wildlife of Northeastern Minnesota and Isle Royale National Park
Castaneda, D.; Isaac, E. J.; Kautz, T.; Romanski, M. C.; Moore, S. A.; Aliota, M.
10.1101/2023.07.14.549077 — microbiology — Posted on 2023-07-15
2330 Pinpoint: trajectory planning for multi-probe electrophysiology and injections in an interactive web-based 3D environment
Birman, D.; Yang, K. J.; West, S. J.; Karsh, B.; Browning, Y.; International Brain Laboratory, ; Siegle, J. H.; Steinmetz, N. A.
10.1101/2023.07.14.548952 — neuroscience — Posted on 2023-07-15
2332 Transcriptomic response in pyroxsulam-resistant and susceptible Bromus sterilis identified three distinct mechanisms of resistance
Sen, M. K.; Hamouzova, K.; Onkokesung, N.; Menendez, J.; Torra, J.; Kosnarova, P.; Sellamuthu, G.; Gupta, A.; Bharati, R.; Sur, V. P.; Roy, A.; Soukup, J.
10.1101/2023.07.14.548957 — plant biology — Posted on 2023-07-15
2333 BERLIN: Basic Explorer for single-cell RNAseq analysis and cell Lineage Determination.
Nobles, G.; Obermayer, A.; Yang, C.-Y.; Zelenka, T.; Nguyen, T.; Chen, Z.; Conejo-Garcia, J.; Avram, D.; Yu, X.; Chen, Y. A.; Shaw, T. I.
10.1101/2023.07.13.548919 — bioinformatics — Posted on 2023-07-15
2338 Wobbly hedgehog syndrome- a progressive neurodegenerative disease
Doss, G. A.; Radecki, D. Z.; Kethireddy, A.; Reilly, M. J.; Pohly, A. E.; August, B. K.; Duncan, I. D.; Samanta, J.
10.1101/2023.07.13.547983 — neuroscience — Posted on 2023-07-15
2345 Solid tumor-on-chip model for efficacy and safety assessment of CAR-T cell therapy
Maulana, T. I.; Teufel, C.; Cipriano, M.; Lazarevski, L.; van den Hil, F. E.; Orlova, V.; Koch, A.; Alb, M.; Hudecek, M.; Loskill, P.
10.1101/2023.07.13.548856 — bioengineering — Posted on 2023-07-15
2347 An expression-directed linear mixed model (edLMM) discovering low-effect genetic variants
Li, Q.; Bian, J.; Qian, Y.; Kossinna, P.; Gordon, P. M.; Zhou, X.; Guo, X.; Yan, J.; Wu, J.; Long, Q.
10.1101/2023.07.13.548939 — genetics — Posted on 2023-07-15
2349 Snowmobile noise alters bird vocalization patterns during winter and pre-breeding season
Cretois, B.; Bick, I. A.; Balantic, C.; Gelderblom, F.; Pavon-Jordan, D.; Wiel, J.; Sethi, S. S.; Betchkal, D.; Banet, B.; Reinen, T. A.
10.1101/2023.07.13.548680 — ecology — Posted on 2023-07-15
2350 Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi
Stuchly, J.; Novak, D.; Brdickova, N.; Hadlova, P.; Iksi, A.; Kuzilkova, D.; Svaton, M.; Engel, P.; Luche, H.; Sousa, A. E.; Almeida, A. R. M.; Kalina, T.
10.1101/2023.07.13.547329 — immunology — Posted on 2023-07-15
2353 Bidirectional Regulation of Motor Circuits Using Magnetogenetic Gene Therapy
Unda, S. R.; Marongiu, R.; Pomeranz, L. E.; Dyke, J. P.; Fung, E. K.; Grosenick, L.; Zirkel, R.; Antoniazzi, A. M.; Norman, S.; Liston, C. M.; Schaffer, C. B.; Nishimura, N.; Stanley, S. A.; Friedman, J. M.; Kaplitt, M. G.
10.1101/2023.07.13.548699 — neuroscience — Posted on 2023-07-15
2355 Sustaining wakefulness: Brainstem connectivity in human consciousness
Edlow, B. L.; Olchanyi, M.; Freeman, H. J.; Li, J.; Maffei, C.; Snider, S. B.; Zollei, L.; Iglesias, J. E.; Augustinack, J.; Bodien, Y. G.; Haynes, R. L.; Greve, D. N.; Diamond, B. R.; Stevens, A.; Giacino, J. T.; Destrieux, C.; van der Kouwe, A.; Brown, E. N.; Folkerth, R. D.; Fischl, B.; Kinney, H. C.
10.1101/2023.07.13.548265 — neuroscience — Posted on 2023-07-15
2358 N-acetylcysteine and acetyl-L-carnitine did not prevent acute PTZ-induced seizure in adult and larvae zebrafish
Chitolina, R.; Reis, C. G.; Stahlhofer-Buss, T.; Linazzi, A.; Benvenutti, R.; Marcon, M.; Herrmann, A. P.; Piato, A.
10.1101/2023.07.13.548882 — neuroscience — Posted on 2023-07-15
2362 Amyloid β accelerates age-related proteome-wide protein insolubility.
Anderton, E.; Chamoli, M.; Bhaumik, D.; King, C. D.; Xie, X.; Foulger, A.; Andersen, J.; Schilling, B.; Lithgow, G.
10.1101/2023.07.13.548937 — systems biology — Posted on 2023-07-15
2363 Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes
Brandt, P. D.; Whittington, D.; Wood, K. D.; Holmquist, C. E.; Nogueira, A. T.; Gaines, C. H.; Brennwald, P. J.; Layton, R. L.
10.1101/2023.07.13.548912 — scientific communication and education — Posted on 2023-07-15
2365 HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data
Myers, M. A.; Arnold, B. J.; Bansal, V.; Mullen, K. M.; Zaccaria, S.; Raphael, B. J.
10.1101/2023.07.13.548855 — cancer biology — Posted on 2023-07-15
2367 Tuning the double lipidation of salmon calcitonin to introduce a pore-like membrane translocation mechanism
Lund, P. M.; Kristensen, K.; Larsen, N. W.; Knuhtsen, A.; Hansen, M. B.; Hjoerringgaard, C. U.; Eriksen, A. Z.; Urquhart, A. J.; Mortensen, K. I.; Simonsen, J. B.; Andresen, T. L.; Larsen, J. B.
10.1101/2023.07.13.548826 — biophysics — Posted on 2023-07-15
2368 Precise Nanopore Signal Modeling Improves Unsupervised Single-Molecule Methylation Detection
Boza, V.; Batmendijn, E.; Peresini, P.; Hodorova, V.; Lichancova, H.; Rabatin, R.; Brejova, B.; Nosek, J.; Vinar, T.
10.1101/2023.07.13.548926 — bioinformatics — Posted on 2023-07-15
2372 Regression and Alignment for Functional Data and Network Topology
Tu, D.; Wrobel, J.; Satterthwaite, T. D.; Goldsmith, J.; Gur, R. C.; Gur, R. E.; Gertheiss, J.; Bassett, D. S.; Shinohara, R. T.
10.1101/2023.07.13.548836 — neuroscience — Posted on 2023-07-15
2375 De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression
Tangudu, N. K.; Buj, R.; Wang, J.; Cole, A. R.; Uboveja, A.; Fang, R.; Amalric, A.; Lyons, M. A.; Chandran, U. R.; Aird, K. M.
10.1101/2023.07.15.549149 — cancer biology — Posted on 2023-07-15
2377 Biohybrid restoration of the hippocampal loop re-establishes the non-seizing state in an in vitro model of limbic seizures
Caron, D.; Buccelli, S.; Canal-Alonso, A.; Farsani, J.; Pruzzo, G.; Linares Barranco, B.; Corchado, J. M.; Chiappalone, M.; Panuccio, G.
10.1101/2023.01.26.525627 — neuroscience — Posted on 2023-07-15
2378 Pan-genome study underling the extent of genomic variation of invasive Streptococcus pneumoniae in Malawi
Iranzadeh, A.; Alisoltani, A.; Kiran, A.; Breiman, R.; Chaguza, C.; Peno, C.; Cornick, J. E.; Everett, D. B.; Mulder, N.
10.1101/2023.01.02.522535 — microbiology — Posted on 2023-07-15
2380 Contribution of host species and pathogen clade to snake fungal disease hotspots in Europe
Blanvillain, G.; Lorch, J.; Joudrier, N.; Bury, S.; Cuenot, T.; Franzen, M.; Freiria, F. M.; Guiller, G.; Halpern, B.; Kolanek, A.; Kurek, K.; Lourdais, O.; Michon, A.; Musilova, R.; Schweiger, S.; Szulc, B.; Ursenbacher, S.; Zinenko, O.; Hoyt, J. R.
10.1101/2022.11.10.515990 — ecology — Posted on 2023-07-15
2382 Statistical Optimization of Hydrazone-Crosslinked Hyaluronic Acid Hydrogels for Protein Delivery
Mozipo, E. A.; Galindo, A. N.; Khachatourian, J. D.; Harris, C. G.; Dorogin, J.; Spaulding, V. R.; Ford, M. R.; Singhal, M.; Fogg, K. C.; Hettiaratchi, M. H.
10.1101/2023.07.14.549125 — bioengineering — Posted on 2023-07-15
2388 Proguanil and chlorhexidine augment the antibacterial activities of clarithromycin and rifampicin against Acinetobacter baumannii
Wang, C.; Zhang, T.; Wang, Y.; Wang, Y.; Pan, H.; Dong, X.; Liu, S.; Cao, M.; Wang, S.; Wang, M.; Li, Y.; Zhang, J.; Hu, W.
10.1101/2023.07.14.549121 — microbiology — Posted on 2023-07-15
2389 Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities
Rodriguez-Salazar, C. A.; van Tol, S.; Mailhot, O.; Galdino, G. T.; Borges Teruel, N. F.; Zhang, L.; Warren, A. N.; Gonzalez-Orozco, M.; Freiberg, A. N.; Najmanovich, R. J.; Giraldo, M. I.; Rajsbaum, R.
10.1101/2023.07.14.549057 — immunology — Posted on 2023-07-15
2391 Visualization and estimation of stroke infarct volumes in rodents
Weber, R. Z.; Bernardoni, D.; Rentsch, N. H.; Achon Buil, B.; Halliday, S.; Augath, M.-A.; Razansky, D.; Tackenberg, C.; Rust, R.
10.1101/2023.07.14.547245 — neuroscience — Posted on 2023-07-15
2392 Single-cell analysis of the nervous system at small and large scales with instant partitions
Frazel, P.; Fricano-Kugler, C.; May-Zhang, A. A.; O'Dea, M. R.; Prakash, P.; Desmet, N.; Lee, H.; Meltzer, R. H.; Fontanez, K.; Hettige, P.; Lithwick-Yanai, G.; Lipson, D.; Luikart, B. W.; Dasen, J. S.; Liddelow, S.
10.1101/2023.07.14.549051 — neuroscience — Posted on 2023-07-15
2394 Role of transporters and enzymes in metabolism and distribution of 4-chlorokynurenine and metabolites
Patel, W.; Shankar, R. G.; Smith, M. A.; Snodgrass, H. R.; Pirmohamed, M.; Jorgensen, A.; Alfirevic, A.; Dickens, D.
10.1101/2023.07.14.548888 — pharmacology and toxicology — Posted on 2023-07-15
2395 Absorption changes in Photosystem II in the Soret band region upon the formation of the chlorophyll cation radical +
Boussac, A.; Sugiura, M.; Nakamura, M.; Nagao, R.; Noguchi, T.; Viola, S.; Rutherford, A. W.; Selles, J.
10.1101/2022.05.12.491653 — biophysics — Posted on 2023-07-15
2398 PlantConnectome: knowledge networks encompassing >100,000 plant article abstracts
Fo, K.; Chuah, Y. S.; Foo, H.; Davey, E. E.; Fullwood, M.; Thibault, G.; Mutwil, M.
10.1101/2023.07.11.548541 — bioinformatics — Posted on 2023-07-15
2399 Federated learning for diagnosis of age-related macular degeneration
Gholami, S.; Lim, J. I.; Leng, T.; Ong, S. S. Y.; Thampson, A. C.; Alam, M. N.
10.1101/2023.07.06.547937 — bioengineering — Posted on 2023-07-15
2405 Multiple Thymic Cell Fate Decisions Regulated by Gads
Shalah, R.; Hallumi, E.; Klopstock, N.; Marzouk, M.; Yablonski, D.
10.1101/2023.07.05.547801 — immunology — Posted on 2023-07-15
2406 ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication
Espada, C. E.; da Rocha, E. L.; Ricciardi-Jorge, T.; dos Santos, A. A.; Soares, Z. G.; Malaquias, G.; Patricio, D. d. O.; Kozlova, E. G.; dos Santos, P. F.; Bordignon, J.; Sanford, T. J.; Fajardo, T.; Sweeney, T.; Bafica, A.; Mansur, D. S.
10.1101/784678 — immunology — Posted on 2023-07-15
2408 Whole-brain annotation and multi-connectome cell typing quantifies circuit stereotypy in Drosophila
Schlegel, P.; Yin, Y.; Bates, A. S.; Dorkenwald, S.; Eichler, K.; Brooks, P.; Han, D. S.; Gkantia, M.; dos Santos, M.; Munnelly, E. J.; Badalamente, G.; Capdevila, L. S.; Sane, V. A.; Pleijzier, M. W.; Tamimi, I. F. M.; Dunne, C. R.; Salgarella, I.; Javier, A.; Fang, S.; Perlman, E.; Kazimiers, T.; Jagannathan, S. R.; Matsliah, A.; Sterling, A. R.; Yu, S.-c.; McKellar, C. E.; FlyWire Consortium, ; Costa, M.; Seung, H. S.; Murthy, M.; Hartenstein, V.; Bock, D. D.; Jefferis, G. S. X. E.
10.1101/2023.06.27.546055 — neuroscience — Posted on 2023-07-15
2409 Spatiotemporal Mapping of Brain Cilia Reveals Region-Specific Oscillation of Length and Orientation
Monfared, R. V.; Abdelkarim, S.; Derdeyn, P.; Chen, K.; Wu, H.; Leong, K.; Chang, T.; Lee, J.; Versales, S.; Nauli, S.; Beier, K.; Baldi, P.; Alachkar, A.
10.1101/2023.06.28.546950 — neuroscience — Posted on 2023-07-15
2413 Legacy effects of precipitation and land use impact maize growth and microbiome assembly under drought stress
Swift, J. F.; Kolp, M. R.; Carmichael, A.; Ford, N. E.; Hansen, P. M.; Sikes, B. A.; Kleiner, M.; Wagner, M. R.
10.1101/2023.04.11.536405 — plant biology — Posted on 2023-07-15
2414 The conserved Arabidopsis PM19L1 protein functions as an osmosensor and regulator of dormancy and germination
Alexander, R. D.; Castillejo-Pons, P.; Melzer, N.; Alsaif, O.; Strotmann, V. I.; Seale, M.; Stahl, Y.; Morris, P. C.
10.1101/2020.08.10.244889 — plant biology — Posted on 2023-07-15
2417 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications
Singh, V.; Itoh, Y.; Del'Olio, S.; Hassan, A.; Naschberger, A.; Flygaard, R. K.; Nobe, Y.; Izumikawa, K.; Aibara, S.; Andrell, J.; Whitford, P.; Barrientos, A.; Taoka, M.; Amunts, A.
10.1101/2023.05.24.542018 — biochemistry — Posted on 2023-07-15
2420 Transcriptomic analysis identifies synapse-enriched lncRNAs required for glutamatergic synapse development and fear memory consolidation.
Samaddar, S.; Srinivasan, B.; Garg, K.; Raj, N.; Sultana, S.; Mukherjee, U.; Banerjee, D.; Liau, W.-S.; Palakodeti, D.; Bredy, T. W.; Banerjee, S.
10.1101/2023.07.14.549055 — neuroscience — Posted on 2023-07-14
2422 Social influences on delayed gratification in New Caledonian crows and Eurasian jays
Miller, R.; Davies, J.; Schiestl, M.; Garcia-Pelegrin, E.; Gray, R. D.; Taylor, A. H.; Clayton, N. S.
10.1101/2023.07.14.549039 — animal behavior and cognition — Posted on 2023-07-14
2423 Differences in cortical surface area in developmental language disorder
Bahar, N.; Cler, G. J.; Krishnan, S.; Asaridou, S. S.; Smith, H. J.; Willis, H. E.; Healy, M. P.; Watkins, K. E.
10.1101/2023.07.13.548894 — neuroscience — Posted on 2023-07-14
2424 In vivo imaging in transgenic songbirds reveals superdiffusive neuron migration in the adult brain
Shvedov, N. R.; Analoui, S.; Dafalias, T.; Bedell, B. L.; Gardner, T. J.; Scott, B. B.
10.1101/2023.07.14.548876 — neuroscience — Posted on 2023-07-14
2426 Single-Molecule RNA Sizing Enables Quantitative Analysis of Alternative Transcription Termination
Patino-Guillen, G.; Boskovic, F.; Pesovic, J.; Panic, M.; Savic-Pavicevic, D.; Keyser, U. F.
10.1101/2023.07.14.549052 — biophysics — Posted on 2023-07-14
2428 CRIMP: A CRISPR/Cas9 Insertional Mutagenesis Protocol and the CRIMP Toolkit
Miles, L. B.; Calcinotto, V.; Sonntag, C.; Lee, C.; Bryson-Richardson, R. J.
10.1101/2023.07.13.548929 — genetics — Posted on 2023-07-14
2429 On the forces shaping diversity and adaptation in the opportunistic pathogen Serratia marcescens
Sterzi, L.; Nodari, R.; Di Marco, F.; Ferrando, M. L.; Saluzzo, F.; Spitaleri, A.; Allahverdi, H.; Papaleo, S.; Panelli, S.; Rimoldi, S. G.; Batisti Biffignandi, G.; Corbella, M.; Cavallero, A.; Prati, P.; Farina, C.; Cirillo, D. M.; Zuccotti, G.; Bandi, C.; Comandatore, F.
10.1101/2023.07.14.548978 — evolutionary biology — Posted on 2023-07-14
2434 Geographic population structure and distinct population dynamics of globally abundant freshwater bacteria
Hoetzinger, M.; Hahn, M. W.; Andersson, L. Y.; Buckley, N.; Ramsin, C.; Buck, M.; Nuy, J. K.; Garcia, S. L.; Puente-Sanchez, F.; Bertilsson, S.
10.1101/2023.07.13.548520 — evolutionary biology — Posted on 2023-07-14
2436 Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts
Trifault, B.; Mamontova, V.; Cossa, G.; Ganskih, S.; Wei, Y.; Hofstetter, J.; Bhandare, P.; Baluapuri, A.; Solvie, D.; Ade, C. P.; Gallant, P.; Wolf, E.; Munschauer, M.; Burger, K.
10.1101/2023.07.14.548979 — molecular biology — Posted on 2023-07-14
2437 Mechanism of target site selection by type V-K CRISPR-associated transposases
George, J. T.; Acree, C.; Park, J.-U.; Kong, M.; Wiegand, T.; Pignot, Y. L.; Kellogg, E. H.; Greene, E. C.; Sternberg, S. H.
10.1101/2023.07.14.548620 — molecular biology — Posted on 2023-07-14
2438 Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility
Stubbusch, A. K. M.; Keegstra, J. M.; Schwartzman, J.; Pontrelli, S.; Clerc, E. E.; Stocker, R.; Magnabosco, C.; Schubert, O. T.; Ackermann, M.; D'Souza, G. G.
10.1101/2023.07.14.548877 — microbiology — Posted on 2023-07-14
2441 Nanoscale clustering by O-antigen-Secretory Immunoglobulin-A binding limits outer membrane diffusion by encaging individual Salmonella cells
Hockenberry, A.; Radiom, M.; Arnoldini, M.; Turgay, Y.; Dunne, M.; Adamcik, J.; Stadtmueller, B.; Mezzenga, R.; Ackermann, M.; Slack, E.
10.1101/2023.07.13.548943 — microbiology — Posted on 2023-07-14
2442 Glycan-specific IgM is critical for human immunity to Staphylococcus aureus
Hendriks, A. M.; Kerkman, P. F.; Varkila, M. R.; Haitsma-Mulier, J. L.; Ali, S.; ten Doesschate, T.; van der Vaart, T. W.; de Haas, C. J. C.; Aerts, P. C.; Cremer, O. L.; Bonten, M. J.; Nizet, V.; Liu, G. Y.; Codee, J. D. C.; Rooijakkers, S. H.; van Strijp, J. A.; van Sorge, N. M.
10.1101/2023.07.14.548956 — microbiology — Posted on 2023-07-14
2443 Bimodal distribution of Candida albicans in children with Autism linked with ASD symptoms
Nirmalkar, K.; Patel, J.; Kang, D.-W.; Bellinghiere, A.; Bowes, D. A.; Adams, J. B.; Krajmalnik-Brown, R.
10.1101/2023.07.13.548908 — microbiology — Posted on 2023-07-14
2444 Performance of amplicon and capture based next-generation sequencing approaches for the epidemiological surveillance of Omicron SARS-CoV-2 and other variants of concern.
Davina-Nunez, C.; Perez, S.; Cabrera-Alvargonzalez, J. J.; Rincon-Quintero, A.; Treinta-Alvarez, A.; Godoy-Diz, M.; Suarez-Luque, S.; Regueiro-Garcia, B.
10.1101/2023.07.14.549026 — microbiology — Posted on 2023-07-14
2453 Genetic variability and vector competence of Aedes aegypti populations from Kisumu and Busia Counties, Western Kenya, for Chikungunya and Zika viruses
Anyango, V. O.; Langat, S.; Mulwa, F.; Mutisya, J.; Koka, H.; Okoyo, C.; Chepkorir, E.; Konongoi, S.; Karanja, A.; Kerubo, G.; Sang, R.; Lutomiah, J.
10.1101/2023.07.14.549035 — microbiology — Posted on 2023-07-14
2455 SQuHIVLa: A novel assay for Specific Quantification of inducible HIV-1 reservoir by LAMP
Hossain, T.; Lungu, C.; de Schrijver, S.; Kuali, M.; Rao, S.; Ngubane, A.; Kan, T. W.; Palstra, R.-J.; Madlala, P.; Ndung'u, T.; Mahmoudi, T.
10.1101/2023.07.14.548928 — microbiology — Posted on 2023-07-14
2456 Absence of CD47 in the tumor microenvironment modulates tumor metabolism and immunosuppressive signatures limiting breast cancer progression.
Stirling, E. R.; Tsai, Y.-T.; Bronson, S. M.; Wilson, A. J.; Westwood, B.; Thomas, A.; Triozzi, P. L.; Furdui, C. M.; Lesser, G. J.; Cook, K. L.; Soto-Pantoja, D. R.
10.1101/2023.07.12.548766 — cancer biology — Posted on 2023-07-14
2457 Validation of human telomere length trans-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as novel human telomere length regulation genes
Keener, R.; Chhetri, S. B.; Connelly, C. J.; Taub, M. A.; Conomos, M. P.; Weinstock, J. S.; Ni, B.; Strober, B. J.; Aslibekyan, S.; Auer, P. L.; Barwick, L.; Becker, L. C.; Blangero, J.; Bleecker, E. R.; Brody, J. A.; Cade, B. E.; Celedon, J. C.; Chang, Y.-C.; Cupples, L. A.; Custer, B.; Freedman, B. I.; Gladwin, M. T.; Heckbert, S. R.; Hou, L.; Irvin, M. R.; Isasi, C. R.; Johnsen, J. M.; Kenny, E. E.; Kooperberg, C.; Minster, R. L.; Nekhai, S.; Pankratz, N.; Peyser, P. A.; Rotter, J. I.; Taylor, K. D.; Telen, M. J.; Wu, B.; Yanek, L. R.; Yang, I. V.; Albert, C.; Arnett, D. K.; Ashley-Koch, A.
10.1101/2023.07.12.548702 — genetics — Posted on 2023-07-14
2459 Fundamental parameters governing the transmission of conjugative plasmids
Rodriguez-Grande, J.; Garcillan-Barcia, M. d. P.; de la Cruz, F.; Fernandez, R.
10.1101/2023.07.11.548640 — microbiology — Posted on 2023-07-14
2461 Transposable elements regulate thymus development and function
Larouche, J.-D.; Laumont, C. M.; Trofimov, A.; Vincent, K.; Hesnard, L.; Brochu, S.; Cote, C.; Humeau, J.; Bonneil, E.; Lanoix, J.; Durette, C.; Gendron, P.; Laverdure, J.-P.; Richie, E. R.; Lemieux, S.; Thibault, P.; Perreault, C.
10.1101/2023.07.12.548732 — immunology — Posted on 2023-07-14
2462 Liebig's law of the minimum in the TGF-β pathway
Li, Y.; Deng, D.; Höfer, C. T.; Kim, J.; Heo, W. D.; Xu, Q.; Liu, X.; Zi, Z.
10.1101/2023.07.10.548398 — systems biology — Posted on 2023-07-14
2464 Differential laboratory passaging of SARS-CoV-2 viral stocks impacts the in vitro assessment of neutralizing antibodies
Avila-Herrera, A.; Kimbrel, J.; Manuel Marti, J.; Thissen, J.; Saada, E.; Weisenberger, T.; Arrildt, K.; Segelke, B.; Allen, J.; Zemla, A. K.; Borucki, M. K.
10.1101/2023.07.14.549044 — molecular biology — Posted on 2023-07-14
2465 Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus
Ketaren, N. E.; Mast, F. D.; Fridy, P. C.; Olivier, J. P.; Sanyal, T.; Sali, A.; Chait, B. T.; Rout, M. P.; Aitchison, J.
10.1101/2023.07.14.549041 — biochemistry — Posted on 2023-07-14
2466 Multivalent Exosome based protein vaccine: a "mix and match" approach to epidemic viruses' challenges.
Cacciottolo, M.; Hsieh, L.-E.; Li, Y.; LeCalire, M. J.; Nice, J. B.; Twaddle, R.; Mora, C. L.; Young, M.; Angeles, J.; Lau, C.; Jin, C.; Elliott, K.; sun, m.
10.1101/2023.07.13.548895 — immunology — Posted on 2023-07-14
2471 Monitoring integrated stress response in live Drosophila
Lidsky, P. V.; Yuan, J.; Lashkevich, K. A.; Dmitriev, S. E.; Andino, R.
10.1101/2023.07.13.548942 — developmental biology — Posted on 2023-07-14
2472 Hif-2α programmes oxygen chemosensitivity in chromaffin cells
Prange-Barczynska, M.; Jones, H.; Sugimoto, Y.; Cheng, X.; Lima, J.; Ratnayaka, I.; Douglas, G.; Buckler, K.; Ratcliffe, P.; Keeley, T.; Bishop, T.
10.1101/2023.07.14.548982 — developmental biology — Posted on 2023-07-14
2474 Role of trafficking protein particle complex 2 in medaka development
De Matteis, M. A.; Zappa, F.; Intartaglia, D.; Guarino, A. M.; De Cegli, R.; Wilson, C.; Salierno, F. G.; Polishchuk, E.; Sorrentino, N. C.; Conte, I.
10.1101/2023.07.14.548998 — cell biology — Posted on 2023-07-14
2475 Serpine1 negatively regulates Th1 cell responses in experimental autoimmune encephalomyelitis.
Akbar, I.; Tang, R.; Baillargeon, J.; Roy, A.-P.; Doss, P. M. I. A.; Zhu, C.; Kuchroo, V. K.; Rangachari, M.
10.1101/2023.07.13.548887 — immunology — Posted on 2023-07-14
2477 Increased Karyopherin Alpha Levels Attenuate Mutant Ataxin-1-Induced Neurodegeneration
Ruff, E. K.; Timperman, D. L.; Amador, A. A.; Aguirre-Lamus, I.; de Haro, M.; Al-Ramahi, I.
10.1101/2023.07.12.548780 — neuroscience — Posted on 2023-07-14
2478 Clonal CD8 T cells in the leptomeninges are locally controlled and influence microglia in human neurodegeneration
Hobson, R.; Levy, S. H. S.; Flaherty, D.; Xiao, H.; Ciener, B.; Reddy, H.; Singal, C.; Teich, A. F.; Shneider, N. A.; Bradshaw, E. M.; Elyaman, W.
10.1101/2023.07.13.548931 — neuroscience — Posted on 2023-07-14
2480 Emergent spatiotemporal patterning of synthetic Notch signal transduction in vivo
Dawson, J.; Bryant, A.; Jordan, T.; Johnson, A.; Langridge, P. D.; Malmi-Kakkada, A. N.
10.1101/2023.07.12.548752 — biophysics — Posted on 2023-07-14
2482 ScreenDMT reveals linoleic acid diols replicably associate with BMI and stimulate adipocyte calcium fluxes
Dreyfuss, J. M.; Djordjilovic, V.; Pan, H.; Bussberg, V.; MacDonald, A. M.; Narain, N. R.; Kiebish, M. A.; Bluher, M.; Tseng, Y.-H.; Lynes, M. D.
10.1101/2023.07.12.548737 — bioinformatics — Posted on 2023-07-14
2486 3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma
Moreno-Jimenez, I.; Heinig, S.; Heras, U.; Maichl, D. S.; Strifler, S.; Leich-Zbat, E.; Blouin, S.; Fratzl, P.; Fratzl-Zelman, N.; Jundt, F.; Cipitria, A.
10.1101/2023.07.12.548656 — bioengineering — Posted on 2023-07-14
2487 A microfluidic strategy to capture antigen-specific high affinity B cells
Alhassan, A. M.; Shirure, V. S.; Luo, J.; Nguyen, B. B.; Rollins, Z. A.; Shergill, B. S.; Zhu, X.; Baumgarth, N.; George, S. C.
10.1101/2023.07.12.548739 — bioengineering — Posted on 2023-07-14
2489 Neighbourhood species richness and drought-tolerance traits modulate tree growth and δ13C responses to drought
Schnabel, F.; Barry, K. E.; Eckhardt, S.; Guillemot, J.; Geilmann, H.; Kahl, A.; Moossen, H.; Bauhus, J.; Wirth, C.
10.1101/2022.11.22.517351 — ecology — Posted on 2023-07-14
2490 Temporal transcriptomic dynamics in developing macaque neocortex
Xu, L.; yuan, z.; Zhou, J.; Zhao, Y.; Liu, W.; Lu, S.; He, Z.; Qiang, B.; Shu, P.; Chen, Y.; Peng, X.
10.1101/2023.07.13.548828 — developmental biology — Posted on 2023-07-14
2493 DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization
Stanczyk, P. J.; Tatekoshi, Y.; Shapiro, J. S.; Nayudu, K.; Chen, Y.; Zeilber, Z.; Schipma, M.; De Jesus, A.; Mahmoodzadeh, A.; Akrami, A.; Chang, H.-C.; Ardehali, H.
10.1101/2023.07.14.549060 — cell biology — Posted on 2023-07-14
2496 Skin surface biomarkers are associated with future development of atopic dermatitis in children with family history of allergic disease
Sato, T.; Nikolovski, J.; Gould, R.; Lboukili, I.; Roux, P.-F.; Al-Ghalith, G.; Orie, J.; Insel, R.; Stamatas, G. N.
10.1101/2023.07.11.548501 — immunology — Posted on 2023-07-14
2498 Extrasynaptic localization is essential for α5GABAA receptor modulation of dopamine system function
McCoy, A.; Prevot, T. D.; Mian, M. Y.; Sharmin, D.; Ahmad, A.; Cook, J.; Sibille, E. D.; Lodge, D.
10.1101/2023.07.12.548744 — neuroscience — Posted on 2023-07-14
2501 A cortical information bottleneck during decision-making
Kleinman, M.; Wang, T.; Xiao, D.; Feghhi, E.; Lee, K.; Carr, N.; Li, Y.; Hadidi, N.; Chandrasekaran, C.; Kao, J.
10.1101/2023.07.12.548742 — neuroscience — Posted on 2023-07-14
2504 Cancer cell - fibroblast crosstalk signature promotes macrophage recruitment via HB-EGF and stromal EGFR/MEK signalling
Giangreco, G.; Rullan, A.; Naito, Y.; Biwas, D.; Liu, Y.-H.; Hooper, S.; Nenclares, P.; Bhide, S.; Cheang, M.; Chakravarty, P.; Hirata, E.; Swanton, C.; Melcher, A.; Harrington, K.; Sahai, E.
10.1101/2023.07.13.548733 — cancer biology — Posted on 2023-07-14
2505 In vivo single-cell CRISPR uncovers distinct TNF-alphaprograms in clonal expansion and tumorigenesis
Renz, P. F.; Ghoshdastider, U.; Baghai Sain, S.; Valdivia-Francia, F.; Khandekar, A.; Ormiston, M.; Bernasconi, M.; Kretz, J. A.; Lee, M.; Hyams, K.; Forny, M.; Pohly, M.; Ficht, X.; Ellis, S. J.; Moor, A. E.; Sendoel, A.
10.1101/2023.07.13.548697 — cancer biology — Posted on 2023-07-14
2506 An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic Microenvironment of Pancreatic Cancer
Co, I. L.; Yu, C.; Lamorte, S.; Ciudad, M. T.; Landon-Brace, N.; Cadavid, J. L.; Xia, Z.; Fomina, A.; Nurse, M.; McGaha, T. L.; Campbell, K. R.; McGuigan, A. P.
10.1101/2023.07.13.548899 — bioengineering — Posted on 2023-07-14
2507 sciMET-cap: High-throughput single-cell methylation analysis with a reduced sequencing burden
Acharya, S.; Nichols, R. V.; Rylaarsdam, L. E.; O'Connell, B. L.; Braun, T. P.; Adey, A. C.
10.1101/2023.07.12.548718 — genetics — Posted on 2023-07-14
2510 Experience sampling reveals the role that covert goal states play in task-relevant behavior.
Mckeown, B.; Strawson, W. H.; Zhang, M.; Turnbull, A.; Konu, D.; Karapanagiotidis, T.; Wang, H.-T.; Leech, R.; Xu, T.; Hardikar, S.; Bernhardt, B.; Margulies, D.; Jefferies, E. S.; Wammes, J.; Smallwood, J.
10.1101/2023.07.12.548563 — neuroscience — Posted on 2023-07-14
2511 A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms
Chen, F.; Wang, Q.; Xiao, M.; Lou, D.; Wufur, R.; Hu, S.; Zhang, Z.; Wang, Y.; Zhang, Y.
10.1101/2022.11.22.517594 — cell biology — Posted on 2023-07-14
2513 Whole-genomes from the extinct Xerces Blue butterfly can help identify declining insect species
de-Dios, T.; Fontsere, C.; Renom, P.; Stiller, J.; Llovera, L.; Uliano-Silva, M.; Sanchez-Gracia, A.; Wright, C.; Lizano, E.; Navarro, A.; Civit, S.; Robbins, R. K.; Blaxter, M.; Marques-Bonet, T.; Vila, R.; Lalueza-Fox, C.
10.1101/2021.11.08.467457 — evolutionary biology — Posted on 2023-07-14
2514 Expression of cell-wall related genes is highly variable and correlates with sepal morphology
Hartasanchez, D. A.; Kiss, A. K.; Battu, V.; Soraru, C.; Delgado Vaquera, A.; Massinon, F.; Braso-Vives, M.; Mollier, C.; Martin-Magnette, M.-L.; Boudaoud, A.; Moneger, F.
10.1101/2022.04.26.489498 — plant biology — Posted on 2023-07-14
2515 Condensin I folds the C. elegans genome
Das, M.; Semple, J. I.; Haemmerli, A.; Volodkina, V.; Scotton, J.; Gitchev, T.; Annan, A.; Campos, J.; Statzer, C.; Dakhovnik, A.; Ewald, C. Y.; Mozziconacci, J.; Meister, P.
10.1101/2022.06.14.495661 — molecular biology — Posted on 2023-07-14
2516 Peripheral direct current suppresses physiologically evoked nociceptive responses at the spinal cord in rodent models of pain
Su, T. F.; Hamilton, J. D.; Guo, Y.; Potas, J. R.; Shivdasani, M. N.; Moalem-Taylor, G.; Fridman, G. Y.; Aplin, F. P.
10.1101/2023.06.07.544048 — neuroscience — Posted on 2023-07-14
2517 Signatures of Jamming in the Cellular Potts Model
Devanny, A. J.; Lee, D. J.; Kampman, L.; Kaufman, L. J.
10.1101/2023.07.10.548321 — biophysics — Posted on 2023-07-14
2519 ImmuNet: A Segmentation-Free Machine Learning Pipeline for Immune Landscape Phenotyping in Tumors by Muliplex Imaging
Sultan, S.; Gorris, M. A. J.; Martynova, E.; van der Woude, L. L.; Buytenhuijs, F.; van Wilpe, S.; Verrijp, K.; Figdor, C. G.; de Vries, I. J. M.; Textor, J.
10.1101/2021.10.22.464548 — immunology — Posted on 2023-07-14
2520 Working memory performance is tied to stimulus complexity
Pusch, R.; Packheiser, J.; Azizi, A. H.; Sevincik, C. S.; Rose, J.; Cheng, S.; Stuettgen, M. C.; Guentuerkuen, O.
10.1101/2021.09.10.459776 — neuroscience — Posted on 2023-07-14
2522 Thalamic regulation of ocular dominance plasticity in adult visual cortex
Qin, Y.; Ahmadlou, M.; Suhai, S.; Neering, P.; de Kraker, L.; Heimel, J. A.; Levelt, C. N.
10.1101/2023.03.23.533941 — neuroscience — Posted on 2023-07-14
2523 xTrimoPGLM: Unified 100B-Scale Pre-trained Transformer for Deciphering the Language of Protein
Chen, B.; Cheng, X.; Gengyang, L.-a.; Li, S.; Zeng, X.; Wang, B.; Gong, J.; Liu, C.; Zeng, A.; Dong, Y.; Tang, J.; Song, L.
10.1101/2023.07.05.547496 — synthetic biology — Posted on 2023-07-14
2526 Neural, physiological and behavioral correlates of empathy for pain in Tourette syndrome
Weiblen, R.; Robert, C.; Petereit, P.; Heldmann, M.; Munte, T. F.; Munchau, A.; Muller-Vahl, K.; Kramer, U. M.
10.1101/2022.12.19.521056 — neuroscience — Posted on 2023-07-14
2527 Single-molecule digital sizing of proteins in solution
Krainer, G.; Jacquat, R. P. B.; Schneider, M. M.; Welsh, T. J.; Fan, J.; Peter, Q. A. E.; Andrzejewska, E. A.; Sneideriene, G.; Czekalska, M. A.; Ausserwoeger, H.; Chai, L.; Arter, W. E.; Saar, K. L.; Herling, T. W.; Franzmann, T. M.; Kosmoliaptsis, V.; Alberti, S.; Hartl, F.-U.; Lee, S. F.; Knowles, T. P. J.
10.1101/2023.07.12.548675 — biophysics — Posted on 2023-07-14
2528 Identifying Protein Conformational States in the PDB and Comparison to AlphaFold2 Predictions
Ellaway, J. I. J.; Anyango, S.; Nair, S.; Zaki, H. A.; Nadzirin, N.; Powell, H. R.; Gutmanas, A.; Varadi, M.; Velankar, S.
10.1101/2023.07.13.545008 — bioinformatics — Posted on 2023-07-14
2531 Stand age diversity weakens forests sensitivity to climate change
Vangi, E.; Cioccolo, E.; Marano, G.; Dalmonech, D.; Bianchini, L.; Puchi, P.; Grieco, E.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2023-07-14
2533 Uncovering novel endolysins against methicillin-resistant Staphylococcus aureus using microbial single-cell genome sequencing
Yoda, T.; Matsuhashi, A.; Matsushita, A.; Shibagaki, S.; Sasakura, Y.; Aoki, K.; Hosokawa, M.; Tsuda, S.
10.1101/2023.06.22.546026 — microbiology — Posted on 2023-07-13
2534 Radial glia control microglial differentiation via integrin avb8-dependent trans-activation of TGFB1
McKinsey, G. L.; Santander, N.; Zhang, X.; Kleemann, K.; Katewa, A.; Tran, L.; Conant, K.; Barraza, M.; Lizama, C. O.; Koo, H. J.; Lee, H.; Mukherjee, D.; Paidassi, H.; Anton, E. S.; Atabai, K.; Sheppard, D.; Butovsky, O.; Arnold, T. D.
10.1101/2023.07.13.548459 — immunology — Posted on 2023-07-13
2535 Exploring the parity paradox: Differential effects on neuroplasticity and neuroinflammation by APOEe4 genotype at middle-age
Lee, B.; Cevizci, M.; Lieblich, S.; Ibrahim, M.; Wen, Y.; Eid, R.; Lamers, Y.; Guterman, P. D.; Galea, L.
10.1101/2023.07.12.548731 — neuroscience — Posted on 2023-07-13
2536 Microstructural Properties of the Cerebellar Peduncles in Children with Developmental Language Disorder
Asaridou, S. S.; Cler, G. J.; Wiedemann, A.; Krishnan, S.; Smith, H. J.; Willis, H. E.; Healy, M. P.; Watkins, K. E.
10.1101/2023.07.13.548858 — neuroscience — Posted on 2023-07-13
2540 The organisation and turnover of synaptic proteins within molecular supercomplexes.
Morris, K.; Bulovaite, E.; Kaizuka, T.; Adams, C.; Komiyama, N.; Grant, S. G. N.; Horrocks, M. H.
10.1101/2023.07.13.548866 — neuroscience — Posted on 2023-07-13
2543 Efficacy of a Pseudomonas aeruginosa Serogroup O9 Vaccine
Moustafa, D. A.; DiGiandomenico, A.; Raghuram, V.; Schulman, M.; Scarff, J.; Davis, M. R.; Varga, J. J.; Dean, C.; Goldberg, J. B.
10.1101/2023.07.13.548830 — microbiology — Posted on 2023-07-13
2554 The transcription factor OCT6 promotes the dissolution of the naive pluripotent state by repressing Nanog and activating a formative state gene regulatory network.
Waisman, A.; Sevlever, F.; Saulnier, D.; Francia, M. G.; Lombardi, A.; Biani, M. C.; Palma, M. B.; Scarafia, A.; Smucler, J.; Amin, G.; La Greca, A.; Moro, L.; Sevlever, G. E.; Guberman, A.; Miriuka, S. G.
10.1101/2023.07.13.548918 — developmental biology — Posted on 2023-07-13
2555 Genetic Screen Identified Prmt5 as a Neuroprotection Target against Cerebral Ischemia
Wu, H.; Lv, P.; Wang, J.; Bennett, B.; Wang, J.; Li, P.; Peng, Y.; Hu, G.; Lin, J.
10.1101/2023.06.26.546470 — cell biology — Posted on 2023-07-13
2556 Enhancing sensitivity and versatility of Tn5 based single cell omics
Seufert, I.; Sant, P.; Bauer, K.; Syed, A. P.; Rippe, K.; Mallm, J.-P.
10.1101/2023.07.13.548833 — molecular biology — Posted on 2023-07-13
2559 TW68, Cryptochromes stabilizer, regulates fasting blood glucose level in ob/ob and fat-induced diabetic mice
Surme, S.; Ergun, C.; Gul, S.; Akyel, Y. K.; Gul, Z. M.; Ozcan, O.; Savglug Ipek, O.; Akarlar, B. A.; Ozlu, N.; Taskin, A. C.; Turkay, M.; Goren, A. C.; Baris, I.; Ozturk, N.; Guzel, M.; Aydin, C.; Okyar, A.; Kavakli, I. H.
10.1101/2023.07.13.548861 — molecular biology — Posted on 2023-07-13
2561 Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues.
Chambers, C. Z.; Soo, G. L.; Engel, A. L.; Birth Defects Research Lab, ; Glass, I. A.; Frassetto, A.; Martini, P.; Cherry, T. J.
10.1101/2023.07.13.548758 — molecular biology — Posted on 2023-07-13
2562 The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions
Nandana, V.; Rathnayaka-Mudiyanselage, I. W.; Muthunayake, N. S.; Hatami, A.; Mousseau, C. B.; Ortiz-Rodriguez, L. A.; Vaishnav, J.; Collins, M.; Gega, A.; Mallikaarachchi, K. S.; Yassine, H.; Ghosh, A.; Biteen, J. S.; Zhu, Y.; Champion, M. M.; Childers, W. S.; Schrader, J. M.
10.1101/2023.01.18.524314 — microbiology — Posted on 2023-07-13
2563 Balancing the scales: Impact of irrigation and pathogen burden on potato blackleg disease and soil microbial communities
Keating, C.; Kilbride, E.; Stalham, M.; Nellist, C.; Milner, J.; Humphris, S.; Toth, I.; Mable, B. K.; Ijaz, U. Z.
10.1101/2023.07.13.548922 — microbiology — Posted on 2023-07-13
2565 Dual Membrane-Sspanning Anti-Sigma Factors Regulate Vesiculation in Gut Bacteroidota
Pardue, E. J.; Sartorio, M.; Jana, B.; Scott, N.; Beatty, W.; Ortiz-Marquez, J.; van Opijnen, T.; Hsu, F.-F.; Potter, R. F.; Feldman, M.
10.1101/2023.07.13.548920 — microbiology — Posted on 2023-07-13
2566 Paranannizziopsis spp. associated with skin lesions in wild snakes in North America and development of a real-time PCR assay for rapid detection of the fungus in clinical samples
Lorch, J. M.; Winzeler, M. E.; Lankton, J. S.; Raverty, S.; Snyman, H. N.; Schwantje, H.; Thacker, C.; Knowles, S.; Cai, H. Y.; Grear, D. A.
10.1101/2023.07.13.548879 — microbiology — Posted on 2023-07-13
2573 Learning from the unknown: exploring the range of bacterial functionality
Mahlich, Y.; Zhu, C.; Chung, H.; Velaga, P. K.; de Paolis Kaluza, M. C.; Radivojac, P.; Friedberg, I.; Bromberg, Y.
10.1101/2022.11.28.518265 — bioinformatics — Posted on 2023-07-13
2576 The DeepFaune initiative: a collaborative effort towards the automatic identification of the French fauna in camera-trap images
Rigoudy, N.; Dussert, G.; Benyoub, A.; Besnard, A.; Birck, C.; Boyer, J.; Bollet, Y.; Bunz, Y.; Caussimont, G.; Chetouane, E.; Chiffard-Carriburu, J.; Cornette, P.; Delestrade, A.; De Backer, N.; Dispan, L.; Le Barh, M.; Duhayer, J.; Elder, J.-F.; Fanjul, J.-B.; Fonderflick, J.; Froustey, N.; Garel, M.; Gaudry, W.; Gerard, A.; Gimenez, O.; Hemery, A.; Hemon, A.; Jullien, J.-M.; Knitter, D.; Malafosse, I.; Marginean, M.; Menard, L.; Ouvrier, A.; Pariset, G.; Prunet, V.; Rabault, J.; Randon, M.; Raulet, Y.; Regnier, A.; Ribiere, R.; Ricci, J.-C.; Ruette, S.; Schneylin, Y.; Sentilles, J.; Siefert
10.1101/2022.03.15.484324 — ecology — Posted on 2023-07-13
2581 Challenging age-related decline in brain function: Evidence from fast neuroimaging of musical sequence recognition
Bonetti, L.; Fernandez-Rubio, G.; Lumaca, M.; Carlomagno, F.; Risgaard Olsen, E.; Criscuolo, A.; Kotz, S. A.; Vuust, P.; Brattico, E.; Kringelbach, M. L.
10.1101/2023.07.13.548815 — neuroscience — Posted on 2023-07-13
2584 Identifying Protein Conformational States in the PDB and Comparison to AlphaFold2 Predictions
Ellaway, J. I. J.; Anyango, S.; Nair, S.; Zaki, H. A.; Nadzirin, N.; Poweel, H. R.; Gutmanas, A.; Varadi, M.; Velankar, S.
10.1101/2023.07.13.545008 — bioinformatics — Posted on 2023-07-13
2586 Characterising neutrophil subtypes in cancer using human and murine single-cell RNA sequencing datasets
Fetit, R.; White, M.; Mills, M. L.; Cortes-Lavaud, X.; McLaren, A.; Falconer, J.; Gilroy, K.; Nixon, C.; Kirschner, K.; Jackstadt, R.; Campbell, A. D.; Sansom, O. J.; Steele, C. W.
10.1101/2023.07.13.548820 — bioinformatics — Posted on 2023-07-13
2590 Recovery of complete genomes of canine parvovirus from clinical samples
Santos, S. F. A.; Souza, U. J. B.; Oliveira, M. T.; Jaime, J.; Spilki, F. R.; Franco, A. C.; Roehe, P. M.; Campos, F. S.
10.1101/2023.07.12.548703 — microbiology — Posted on 2023-07-13
2591 Utility of nasal swabs for assessing mucosal immune responses towards SARS-CoV-2
Roubidoux, E. K.; Brigleb, P. H.; Vegesana, K.; Souquette, A.; Whitt, K.; Freiden, P.; St. Jude Investigative Team, ; Green, A.; Thomas, P. G.; McGargill, M. A.; Wolf, J.; Schultz-Cherry, S.
10.1101/2023.07.12.548630 — immunology — Posted on 2023-07-13
2592 Analysis of a European general wildlife health surveillance program: chances, challenges and recommendations
Heiderich, E.; Keller, S. A.; Mirjam, P.; Origgi, F. C.; Zuercher-Giovanni, S.; Borel, S.; Marti, I.; Pisano, S. R. R.; Friker, B.; Adrian-Kalchhauser, I.; Ryser-Degiorgis, M.-P.
10.1101/2023.07.13.548813 — zoology — Posted on 2023-07-13
2593 Machine Learning identifies conserved traits that influence lifespan and healthspan responses to dietary restriction
Hilsabeck, T. A.; Narayan, V. P.; Wilson, K. A.; Carrera, E.; Raftery, D.; Promislow, D. E.; Brem, R. B.; Campisi, J. A.; Kapahi, P.
10.1101/2023.07.09.548232 — systems biology — Posted on 2023-07-13
2596 Differential leaf flooding resilience in Arabidopsis thaliana is controlled by age-dependent ORESARA1 activity
Rankenberg, T.; van Veen, H.; Sedaghatmehr, M.; Liao, C.-Y.; Devaiah, M. B.; Balazadeh, S.; Sasidharan, R.
10.1101/2022.11.23.517613 — plant biology — Posted on 2023-07-13
2597 Patterning of phase-separated condensates by Dnd1 controls cell fate
Westerich, K. J.; Tarbashevich, K.; Gupta, A.; Zhu, M.; Hull, K.; Romo, D.; Gross-Thebing, T.; Raz, E.
10.1101/2022.10.20.512863 — cell biology — Posted on 2023-07-13
2598 Single-molecule tracking reveals dual front door/back door inhibition of Cel7A cellulase by its product cellobiose
Nong, D.; Haviland, Z. K.; Zexer, N.; Pfaff, S. A.; Cosgrove, D. J.; Tien, M.; Anderson, C. T.; Hancock, W. O.
10.1101/2023.07.13.548867 — plant biology — Posted on 2023-07-13
2601 Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures
Barnett, K. R.; Mobley, R. J.; Diedrich, J. D.; Bergeron, B. P.; Bhattarai, K. R.; Yang, W.; Crews, K. R.; Manring, C. S.; Jabbour, E.; Paietta, E.; Litzow, M. R.; Kornblau, S. M.; Stock, W.; Inaba, H.; Jeha, S.; Pui, C.-H.; Mullighan, C. G.; Relling, M. V.; Yang, J. J.; Evans, W. E.; Savic, D.
10.1101/2023.02.14.528493 — genomics — Posted on 2023-07-13
2603 Trafficking Machinery is Rapidly Primed to Facilitate Polarised IL-6 Secretion in Dendritic Cells
Warner, H. M.; Chen, T.; Mahajan, S.; ter Beest, M.; Linders, P.; Franciosa, G.; Bianchi, F.; van den Bogaart, G.
10.1101/2023.07.13.548819 — cell biology — Posted on 2023-07-13
2605 Dysfunctional Hippocampal-Prefrontal Network Underlies a Multidimensional Neuropsychiatric Phenotype following Early-Life Seizure
Ruggiero, R. N.; Marques, D. B.; Rossignoli, M. T.; De Ross, J. B.; Prizon, T.; Beraldo, I. J. S.; Bueno-Junior, L. S.; Kandratavicius, L.; Peixoto-Santos, J. E.; Aguiar, C. L.; Leite, J. P.
10.1101/2022.12.21.521438 — neuroscience — Posted on 2023-07-13
2606 Hue selectivity from recurrent circuitry in Drosophila
Christenson, M. P.; Sanz Diez, A.; Heath, S. L.; Saavedra-Weisenhaus, M.; Adashi, A.; Abbott, L.; Behnia, R.
10.1101/2023.07.12.548573 — neuroscience — Posted on 2023-07-13
2607 Teosinte Pollen Drive guides maize domestication and evolution by RNAi
Berube, B.; Ernst, E.; Cahn, J.; Roche, B.; de Santis Alves, C.; Lynn, J.; Scheben, A.; Siepel, A.; Ross-Ibarra, J.; Kermicle, J.; Martienssen, R. A.
10.1101/2023.07.12.548689 — plant biology — Posted on 2023-07-13
2608 Stand age diversity weakens forests sensitivity to climate change
Vangi, E.; Cioccolo, E.; Marano, G.; Dalmonech, D.; Bianchini, L.; Puchi, P.; Grieco, E.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2023-07-13
2615 A genome catalogue of lake bacteria across watershed land use gradients at a continental scale
Garner, R.; Kraemer, S.; Onana, V. E.; Fradette, M.; Varin, M.-P.; Huot, Y.; Walsh, D. A.
10.1101/2022.08.12.503676 — microbiology — Posted on 2023-07-13
2616 Pervasive inter-individual differences in the sensorimotor-association axis of cortical organization
Bignardi, G.; Nivard, M. G.; Schaare, H. L.; Bernhardt, B. C.; Bethlehem, R. A. I.; Fisher, S. E.; Valk, S. L.
10.1101/2023.07.13.548817 — neuroscience — Posted on 2023-07-13
2619 In Vivo Monitoring of Cellular Senescence by Photoacoustic and Fluorescence Imaging Utilizing a Nanostructured Organic Probe
Baker, A. G.; Ou, H.-L.; Hartono, M.; Popov, A. B.; Brown, E. L.; Joseph, J.; Golinska, M.; Sanghera, C.; Gonzalez-Gualda, E.; Macias, D.; Else, T. R.; Greer, H. F.; Vernet, A.; Bohndiek, S. E.; Fruk, L.; Munoz-Espin, D.
10.1101/2023.07.12.548691 — cancer biology — Posted on 2023-07-13
2620 Empirical modeling of a single polymer collapsing under the entropic pressure of neutral crowders
Chaboche, Q.; Campos-Villalobos, G.; Giunta, G.; Dijkstra, M.; Cosentino Lagomarsino, M.; Scolari, V. F.
10.1101/2023.07.12.548683 — biophysics — Posted on 2023-07-13
2622 3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma
Moreno-Jimenez, I.; Heinig, S.; Heras, U.; Maichl, D. S.; Strifler, S.; Leich-Zbat, E.; Blouin, S.; Fratzl, P.; Fratzl-Zelman, N.; Jundt, F.; Cipitria, A.
10.1101/2023.07.12.548656 — bioengineering — Posted on 2023-07-13
2625 Coexistence of many species under a random competition-colonization trade-off
Miller, Z. R.; Clenet, M.; Della Libera, K.; Massol, F.; Allesina, S.
10.1101/2023.03.23.533867 — ecology — Posted on 2023-07-13
2628 Stand age diversity dampens forests sensitivity to climate change
Vangi, E.; Cioccolo, E.; Marano, G.; Dalmonech, D.; Bianchini, L.; Puchi, P.; Grieco, E.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2023-07-13
2629 Resistance exercise protects mice from protein-induced fat accretion
Trautman, M. E.; Braucher, L. N.; Elliehausen, C.; Zhu, W. G.; Zelenovskiy, E.; Green, M.; Sonsalla, M. M.; Yeh, C.-Y.; Hornberger, T. A.; Konopka, A. R.; Lamming, D. W.
10.1101/2022.10.18.512689 — physiology — Posted on 2023-07-13
2631 AI2BMD: efficient characterization of protein dynamics with ab initio accuracy
Wang, T.; He, X.; Li, M.; Wang, Y.; Wang, Z.; Li, S.; Shao, B.; Liu, T.-Y.
10.1101/2023.07.12.548519 — bioinformatics — Posted on 2023-07-13
2632 SNM1A (DCLRE1A) is required for the efficient repair of complex DNA breaks in human cells
Swift, L. P.; Lagerholm, B. C.; Baddock, H. T.; Henderson, L. R.; Ratnaweera, M.; Sengerova, B.; Lee, S. Y.; Cruz-Migoni, A.; Waithe, D.; Renz, C.; Ulrich, H. D.; Newman, J. A.; schofield, C. J.; McHugh, P. J.
10.1101/2022.07.21.500940 — biochemistry — Posted on 2023-07-13
2633 Biodiversity monitoring in Europe: user and policy needs
Moersberger, H.; Valdez, J. W.; Martin, J. G. C.; Junker, J.; Georgieva, I.; Bauer, S.; Beja, P.; Breeze, T. D.; Fernandez, M.; Fernandez, N.; Brotons, L.; Jandt, U.; Bruelheide, H.; Kissling, D. W.; Langer, C.; Liquete, C.; Lumbierres, M.; Solheim, A. L.; Maes, J.; Moran-Ordonez, A.; Moreira, F.; Pe'er, G.; Santana, J.; Shamoun-Baranes, J.; Smets, B.; Capinha, C.; McCallum, I.; Pereira, H. M.; Bonn, A.
10.1101/2023.07.12.548673 — ecology — Posted on 2023-07-13
2634 Parasites make hosts more profitable but less available to predators
Prosnier, L.; Loeuille, N.; Hulot, F. D.; Renault, D.; Piscart, C.; Bicocchi, B.; Deparis, M.; Lam, M.; Medoc, V.
10.1101/2022.02.08.479552 — ecology — Posted on 2023-07-13
2637 Quantifying the coverage of the human proteome with renewable antibodies
Ayoubi, R.; Ryan, J.; Fotouhi, M.; Alshafie, W.; Bolivar, S. G.; Moleon, V. R.; Reintsch, W.; Eckmann, P.; Worrall, D.; McDowell, I.; Southern, K.; Durcan, T. M.; Brown, C. M.; Bandrowski, A. E.; Virk, H. S.; Edwards, A. M.; McPherson, P. S.; Laflamme, C.
10.1101/2023.06.01.543292 — molecular biology — Posted on 2023-07-13
2638 SMU_1361c regulates the oxidative stress response of Streptococcus mutans
Yu, S.; Huang, J.; Liu, Y.; Li, J.; Zhang, Q.; Wang, Y.; Gong, T.; Ma, Q.; Zou, J.; Li, Y.
10.1101/2023.07.10.548324 — microbiology — Posted on 2023-07-13
2639 A bacterial microbiome is dispensable for the induction of CD8 T cell exhaustion
Kuhlmann, M.; Kolland, D. D. C.; Almeida, G. P. d.; Hoffmann, C.; von Hoesslin, M.; Berner, J.; Wurmser, C.; Ohnmacht, C.; Zehn, D.
10.1101/2022.10.03.510696 — immunology — Posted on 2023-07-13
2640 Mechanisms of Innate Immune Injury in Arrhythmogenic Cardiomyopathy
Chelko, S. P.; Penna, V.; Engel, M.; Landim-Vieira, M.; Cannon, E. N.; Lavine, K.; Saffitz, J. E.
10.1101/2023.07.12.548682 — immunology — Posted on 2023-07-13
2642 Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same construct.
de Guglielmo, G.; Carrette, L.; Kallupi, M.; Brennan, M.; Boomhower, B.; Maturin, L.; Conlisk, D.; Sedighim, S.; Tieu, L.; Fannon, M.; Martinez, A. R.; Velarde, N.; Othman, D.; Sichel, B.; Ramboger, J.; Lau, J.; Kononoff, J.; Kimbrough, A.; Simpson, S.; Smith, L.; Shankar, K.; Sneddon, E. A.; Bonnet-Zahedi, S.; Avelar, A.; Crook, C.; Chun, L.; Vang, A.; Milan, K.; Schweitzer, P.; Lin, B.; Peng, B.; Chitre, A.; Polleskaya, O.; Woods, L. S.; Palmer, A. A.; George, O.
10.1101/2021.07.22.453410 — neuroscience — Posted on 2023-07-13
2644 Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro
Vu, D.-D.; Bonucci, A.; Breniere, M.; Cisneros-Aguirre, M.; Pelupessy, P.; Wang, Z.; Carlier, L.; Bouvignies, G.; Cortes, P.; Aggarwal, A. K.; Blackledge, M.; Gueroui, Z.; Belle, V.; STARK, J. M.; Modesti, M. M.; Ferrage, F.
10.1101/2023.07.12.548668 — biophysics — Posted on 2023-07-13
2645 Single-molecule digital sizing of proteins in solution
Krainer, G.; Jacquat, R. P. B.; Schneider, M. M.; Welsh, T. J.; Fan, J.; Peter, Q. A. E.; Andrzejewska, E. A.; Sneideriene, G.; Czekalska, M. A.; Ausserwoeger, H.; Chai, L.; Arter, W. E.; Saar, K. L.; Herling, T. W.; Franzmann, T. M.; Kosmoliaptsis, V.; Alberti, S.; Hartl, F.-U.; Lee, S. F.; Knowles, T. P. J.
10.1101/2023.07.12.548675 — biophysics — Posted on 2023-07-13
2646 Integration of variant annotations using deep set networks boosts rare variant association genetics
Clarke, B.; Holtkamp, E.; Ozturk, H.; Muck, M.; Wahlberg, M.; Meyer, K.; Munzlinger, F.; Brechtmann, F.; Holzlwimmer, F. R.; Gagneur, J.; Stegle, O.
10.1101/2023.07.12.548506 — bioinformatics — Posted on 2023-07-13
2648 Identifying novel radioprotective drugs via salivary gland tissue chip screening
Piraino, L.; Chen, C.; Mereness, J.; Dunman, P.; Ovitt, C.; Benoit, D.; DeLouise, L. A.
10.1101/2023.07.12.548707 — bioengineering — Posted on 2023-07-13
2651 Polo-like kinase 1 regulates immune synapse assembly and cytotoxic T cell function by driving microtubule dynamics
Zevolini, F.; Onnis, A.; Khazen, R.; Mueller, S.; Marotta, G.; Valiltutti, S.; Finetti, F.; Baldari, C.
10.1101/2023.07.12.548674 — immunology — Posted on 2023-07-13
2652 A characterization of cardiac-induced noise in R2* maps of the brain
Raynaud, Q.; Di Domenicantonio, G.; Yerly, J.; Dardano, T.; van Heeswijk, R. B.; Lutti, A.
10.1101/2022.12.19.521028 — neuroscience — Posted on 2023-07-13
2653 reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics
Ruiz, J. L.; Terron-Camero, L. C.; Castillo-Gonzalez, J.; Fernandez-Rengel, I.; Delgado, M.; Gonzalez-Rey, E.; Andres-Leon, E.
10.1101/2023.07.12.548663 — bioinformatics — Posted on 2023-07-13
2654 Identification of microbial exopolymer producers in sandy and muddy intertidal sediments by compound-specific isotope analysis
Hubas, C.; Gaubert-Boussarie, J.; D'Hondt, A.-S.; Jesus, B.; Lamy, D.; Meleder, V.; Prins, A.; Rosa, P.; Stock, W.; Sabbe, K.
10.1101/2022.12.02.516908 — ecology — Posted on 2023-07-13
2656 Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
Mavrommatis, L.; Jeong, H.-W.; Kindler, U.; Gomez-Giro, G.; Kienitz, M.-C.; Stehling, M.; Psathaki, O. E.; Zeuschner, D.; Bixel, G.; Han, D.; Morosan-Puopolo, G.; Gerovska, D.; Yang, J. H.; Kim, J. B.; Arauzo-Bravo, M. J.; Schwamborn, J. C.; Hahn, S. A.; Adams, R. H.; Scholer, H. R.; Vorgerd, M.; Brand-Saberi, B.; Zaehres, H.
10.1101/2020.09.14.295832 — bioengineering — Posted on 2023-07-13
2657 Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob Disease risk gene Stx6
Jones, E.; Hill, E.; Linehan, J.; Nazari, T.; Caulder, A.; Codner, G. F.; Hutchison, M.; Mackenzie, M.; Farmer, M.; Coysh, T.; Wiggins De Oliveira, M.; Al-Doujaily, H.; Sandberg, M.; Vire, E.; Cunningham, T. J.; Asante, E. A.; Brandner, S.; Collinge, J.; Mead, S.
10.1101/2023.01.10.523281 — neuroscience — Posted on 2023-07-13
2659 Tessellation Of Artificial Touch Via Microstimulation Of Human Somatosensory Cortex
Greenspon, C. M.; Shelchkova, N. D.; Valle, G.; Hobbs, T.; Berger-Wolf, E. I.; Hutchison, B. C.; Dogruoz, E.; Verbarschott, C.; Callier, T.; Sobinov, A.; Okorokova, E. V.; Jordan, P. M.; Prasad, D.; He, Q.; Liu, F.; Kirsch, R. F.; Miller, J. P.; Lee, R. C.; Satzer, D.; Gonzalez-Martinez, J.; Warnke, P.; Miller, L. E.; Boninger, M. L.; Ajiboye, B. B.; Graczyk, E. L.; Downey, J. E.; Collinger, J.; Hatsopoulos, N.; Gaunt, R.; Bensmaia, S. J.
10.1101/2023.06.23.545425 — neuroscience — Posted on 2023-07-13
2661 Septin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function.
De Gasperi, R.; Csernoch, L.; Dienes, B.; Gonczi, M.; Chakrabarty, J. K.; Goeta, S.; Aslan, A.; Toro, C. A.; Karasik, D.; Brown, L. M.; Brotto, M.; Cardozo, C. P.
10.1101/2023.05.11.540467 — physiology — Posted on 2023-07-13
2662 Estimating causality between smoking and abdominal obesity by Mendelian randomization
Carrasquilla, G. D.; Garcia-Urena, M.; Romero Lado, M. J.; Kilpeläinen, T.
10.1101/2022.06.06.494971 — genomics — Posted on 2023-07-13
2663 Recent emergence of cephalosporin resistant Salmonella Typhi carrying IncFIB(K) plasmid encoding blaCTX-M-15 gene in India
Thirumoorthy, T. P.; Jacob, J. J.; V, A.; T, M. P.; M, Y.; Shah, B. S.; Iyer, V.; Shah, A.; Gaigawale, A.; Patel, P.; Mutreja, A.; John, J.; Kang, G.; Veeraraghavan, B.
10.1101/2023.07.05.547856 — genomics — Posted on 2023-07-13
2664 Chromosomal-level genome assembly of Populus lasiocarpa
Long, Z.; Sang, Y.; Feng, J.; Shi, T.; Dan, X.; Zhang, Y.; Liu, J.; Wang, J.
10.1101/2023.07.11.548483 — genomics — Posted on 2023-07-13
2666 Efflux pumps mediate changes to fundamental bacterial physiology via membrane potential
Whittle, E. E.; Orababa, O.; Osgerby, A.; Element, S. J.; Blair, J. M. A.; Overton, T. W.
10.1101/2023.04.03.535035 — microbiology — Posted on 2023-07-13
2667 Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells
Morgun, E.; Zhu, J.; Almunif, S.; Bobbala, S.; Aguilar, M. S.; Wang, J.; Conner, K.; Cui, Y.; Cao, L.; Seshadri, C.; Scott, E. A.; Wang, C.-R.
10.1101/2023.03.07.531489 — immunology — Posted on 2023-07-13
2671 Deep learning permits imaging of multiple structures with the same fluorophores
Jin, L.; Liu, J.; Zhang, H.; Zhu, Y.; Yang, H.; Wang, J.; Zhang, L.; Xu, Y.; Kuang, C.; Liu, X.
10.1101/2023.02.03.526797 — biophysics — Posted on 2023-07-13
2673 Specialized mesenteric lymphatic capillaries by-pass the mesenteric lymph node chain to transport peritoneal antigens directly into mediastinal lymph nodes.
Redder, E.; Kirschnick, N.; Fang, S.; Kuhlmann, M.; Gonzalez-Loyola, A.; Wyss, T.; Stehling, M.; Adams, R. H.; Petrova, T. V.; Alitalo, K. K.; Rot, A.; Kiefer, F.
10.1101/2023.07.11.548304 — developmental biology — Posted on 2023-07-13
2674 Evaluation of single-sample network inference methods for precision oncology
Deschildere, J.; Vandemoortele, B.; Loers, J. U.; De Preter, K.; Vermeirssen, V.
10.1101/2023.07.11.548508 — systems biology — Posted on 2023-07-12
2676 Modular and integrative activity reporters enhance biochemical studies in the yeast ER.
Martinusen, S. G.; Slaton, E. W.; Nelson, S. E.; Pulgar, M. A.; Besu, J. T.; Simas, C. F.; Denard, C. A.
10.1101/2023.07.12.548713 — synthetic biology — Posted on 2023-07-12
2680 Transkingdom mechanism of MAMP generation by chitotriosidase (CHIT1) feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing
Chang, T.-H.; Gloria, Y. C.; Hellmann, M. J.; Greve, C.-L.; Le Roy, D.; Roger, T.; Bork, F.; Bugl, S.; Jakob, J.; Kasper, L.; Hube, B.; Pusch, S.; Gow, N.; Sorlie, M.; Tondervik, A.; Moerschbacher, B.; Weber, A. N. R.
10.1101/2022.02.17.479713 — immunology — Posted on 2023-07-12
2682 A novel naive Bayes approach to identifying grooming behaviors in the force-plate actometric platform
Anderson, C. J.; Cadeddu, R.; Anderson, D. N.; Huxford, J. A.; VanLuik, E. R.; Odeh, K.; Pittenger, C.; Pulst, S. M.; Bortolato, M.
10.1101/2023.07.08.548198 — neuroscience — Posted on 2023-07-12
2684 Multiscale entropy analysis of combined EEG-fNIRS measurement in preterm neonates
Semeia, L.; Nourhashemi, M.; Mahmoudzadeh, M.; Wallois, F.; Sippel, K.; Preissl, H.
10.1101/2023.07.12.548724 — neuroscience — Posted on 2023-07-12
2688 Eye lens organoids going simple: characterization of a new 3-dimensional organoid model for lens development and pathology
Duot, M.; Viel, R.; Viet, J.; Le Goff-Gaillard, C.; Paillard, L.; Lachke, S.; Gautier-Courteille, C.; Reboutier, D.
10.1101/2023.07.12.548679 — cell biology — Posted on 2023-07-12
2689 Longstanding auditory sensory and semantic differences in preterm born children
Retsa, C.; Turpin, H.; Geiser, E.; Ansermet, F.; Muller-Nix, C.; Murray, M. M.
10.1101/2023.07.12.548657 — neuroscience — Posted on 2023-07-12
2692 Pharmacological characterization and radiolabeling ofVUF15485, a high-affinity small-molecule agonist for theatypical chemokine receptor ACKR3
Zarca, A.; Adlere, I.; Viciano, C. P.; Arimont-Segura, M.; Meyrath, M.; Simon, I. A.; Bebelman, J. P. M.; Laan, D.; Custers, H. G. J.; Janssen, E. C.; Versteegh, K. L.; Bosma, R.; De Esch, I. J. P.; Vischer, H. F.; Wijtmans, M.; Szpakowska, M.; Chevigne, A.; Hoffmann, C.; de Graaf, C.; Zarzycka, B. A.; Windhorst, A. D.; Smit, M. J.; Leurs, R.
10.1101/2023.07.12.548622 — pharmacology and toxicology — Posted on 2023-07-12
2694 Multiplexed effector screening for recognition by endogenous resistance genes using positive defense reporters in wheat protoplasts
Wilson, S.; Dagvadorj, B.; Tam, R.; Murphy, L.; Heng, N.; Crean, E.; Greenwood, J.; Rathjen, J.; Schwessinger, B.
10.1101/2023.04.30.538885 — plant biology — Posted on 2023-07-12
2696 Epitope Engineered Human Haematopoietic Stem Cells are Shielded from CD123-targeted Immunotherapy
Marone, R.; Landmann, E.; Devaux, A.; Lepore, R.; Seyres, D.; Zuin, J.; Burgold, T.; Engdahl, C.; Capoferri, G.; DellAglio, A.; Larrue, C.; Simonetta, F.; Rositzka, J.; Rhiel, M.; Andrieux, G.; Gallagher, D.; Schroeder, M.; Wiederkehr, A.; Sinopoli, A.; Do Sacramento, V.; Haydn, A.; Garcia-Prat, L.; Divsalar, C.; Camus, A.; Xu, L.; Bordoli, L.; Schwede, T.; Porteus, M.; Tamburini Bonnefoy, J.; Corn, J. E.; Cathomen, T.; Cornu, T. I.; Urlinger, S.; Jeker, L. T.
10.1101/2023.07.11.547391 — bioengineering — Posted on 2023-07-12
2698 A fast-slow trait continuum at the level of entire communities
Neyret, M.; Le Provost, G.; Boesing, A. L.; Schneider, F. D.; Baulechner, D.; Bergmann, J.; de Vries, F.; Fiore-Donno, A. M.; Geisen, S.; Goldmann, K.; Kuechler, A.; Saifutdinov, R.; Simons, N. K.; Tobias, J.; Zaitsev, A. S.; Gossner, M. M.; Jung, K.; Kandeler, E.; Krauss, J.; Penone, C.; Schloter, M.; Schulz, S.; Staab, M.; Wolters, V.; Apostolakis, A.; Birkhofer, K.; Boch, S.; Boeddinghaus, R. S.; Bolliger, R.; Bonkowski, M.; Buscot, F.; Dumack, K.; Fischer, M.; Gan, H. Y.; Heinze, J.; Hoelzel, N.; John, K.; Klaus, V.; Kleinebecker, T.; Marhan, S.; Mueller, J.; Renner, S. C.; Rillig, M.; Sch
10.1101/2023.07.12.548516 — ecology — Posted on 2023-07-12
2699 Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation
Amir, S.; Arowolo, O.; Mironova, E.; McGaunn, J.; Oluwayiose, O.; Sergeyev, O.; Pilsner, J. R.; Suvorov, A.
10.1101/2023.05.23.541978 — developmental biology — Posted on 2023-07-12
2700 Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport
Wu, Y.; Ding, C.; Weinreb, A.; Manning, L.; Swaim, G.; Yogev, S.; Colon-Ramos, D.; Hammarlund, M.
10.1101/2023.07.12.548706 — cell biology — Posted on 2023-07-12
2701 The Septin Cytoskeleton is Required for Plasma Membrane Repair
Prislusky, M. I. A.; Lam, J. G.; Ruiz Contreras, V.; Ng, M.; Chamberlain, M.; Fields, M.; Zhang, X.; Amer, A.; Seveau, S. M.
10.1101/2023.07.12.548547 — cell biology — Posted on 2023-07-12
2702 Fungal-bacterial gut microbiota interactions in patients with Clostridioides difficile colonisation and infection
Henderickx, J. G. E.; Crobach, M. J. T.; Terveer, E. M.; Smits, W. K.; Kuijper, E. J.; Zwittink, R. D.
10.1101/2023.07.12.548349 — microbiology — Posted on 2023-07-12
2707 AAV-mediated Delivery of Plakophilin-2a Arrests Progression of Arrhythmogenic Right Ventricular Cardiomyopathy in Murine Hearts: Preclinical Evidence Supporting Gene Therapy in Humans
van Opbergen, C. J.; Narayanan, B.; Sacramento, C. B.; Stiles, K. M.; Mishra, V.; Frenk, E.; Ricks, D.; Chen, G.; Zhang, M.; Yarabe, P.; Schwartz, J.; Delmar, M.; Herzog, C. D.; Cerrone, M.
10.1101/2023.07.12.548590 — physiology — Posted on 2023-07-12
2708 Lung injury shifts pulmonary capillary endothelial cells towards regeneration-associated Lrg1+ subpopulations with delayed dynamics in aged mice
Truchi, M.; Savary, G.; Cadis, H.; Lebrigand, K.; Baeri, A.; Lingampally, A.; Girard-Riboulleau, C.; Scribe, C.; Magnone, V.; Arguel, M.-J.; de Schutter, C.; Gautier-Isola, M.; Fassy, J.; Rezzonico, R.; Larrue, R.; Pluquet, O.; Perrais, M.; Hofman, V.; Marquette, C.-H.; Hofman, P.; Günther, A.; Ricard, N.; BARBRY, P.; Leroy, S.; Cauffiez, C.; Bellusci, S.; Vassaux, G.; Pottier, N.; Mari, B.
10.1101/2023.07.11.548522 — pathology — Posted on 2023-07-12
2710 NNV024, a novel humanized anti-CD37 antibody with enhanced ADCC and prolonged plasma half-life in human FcRn transgenic mice for treatment of NHL
Generaloc, R.; Fiorito, E.; Foss, S.; Pascal, V.; Heyerdahl, H.; Repetto, A.; Andersen, J. T.; Tjonnfjord, G.; Skanland, S. S.; Dahle, J.
10.1101/2023.07.12.548667 — cancer biology — Posted on 2023-07-12
2714 Chromosomal-level genome assembly of Populus adenopoda
Liu, S.; Wang, Z.; Shi, T.; Dan, X.; Zhang, Y.; Liu, J.; Wang, J.
10.1101/2023.07.11.548479 — genomics — Posted on 2023-07-12
2715 High throughput PRIME editing screens identify functional DNA variants in the human genome
Ren, X.; Yang, H.; Nierenberg, J. L.; Sun, Y.; Chen, J.; Beaman, C.; Pham, T.; Nobuhara, M.; Takagi, M. A.; Narayan, V.; Li, Y.; Ziv, E.; Shen, Y.
10.1101/2023.07.12.548736 — genomics — Posted on 2023-07-12
2716 Chromosomal-level genome assembly of Populus davidiana
Chen, L.; Jiang, Y.; Shi, T.; Jia, C.; Long, Z.; Zhang, X.; Sang, Y.; Liu, J.; Wang, J.
10.1101/2023.07.11.548481 — genomics — Posted on 2023-07-12
2721 Skeletal progenitor LRP1-mediated endocytosis is critical for synovial joint formation and bone growth
Alhashmi, M.; Gremida, A. M.; Al-Maslamani, N. A.; Liu, K.; Sutherland, H.; Wilson, P.; Clegg, P.; Bou-Gharios, G.; Yamamoto, K.
10.1101/2023.07.11.548556 — developmental biology — Posted on 2023-07-12
2722 Modulation of tooth regeneration through opposing responses to Wnt and BMP signals in teleosts
Square, T. A.; Mackey, E. J.; Sundaram, S.; Weksler, N. C.; Chen, Z. Z.; Narayanan, S. N.; Miller, C. T.
10.1101/2022.10.01.510447 — developmental biology — Posted on 2023-07-12
2723 Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a-Mutant Hematopoietic Stem Cells
Schwartz, L. S.; Young, K. A.; Stearns, T. M.; Boyer, N.; Mujica, K. D.; Trowbridge, J. J.
10.1101/2023.07.12.548764 — cell biology — Posted on 2023-07-12
2726 Stress-Induced Mucin 13 Reductions Drive Intestinal Microbiome Shifts and Despair Behaviors
Rivet-Noor, C.; Merchak, A. R.; Render, C.; Gay, N.; Beiter, R. M.; Brown, R.; Keeler, A.; Moreau, G. B.; Li, S.; Olgun, D.; Steigmeyer, A. D.; Ofer, R.; Phan, T. M. H.; Vemuri, K.; Chen, L.; Mahoney, K.; Shin, J.-B.; Malaker, S. A.; Deppmann, C. D.; Verzi, M.; Gaultier, A.
10.1101/2022.10.13.512135 — microbiology — Posted on 2023-07-12
2728 The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113
Podlesainski, D.; Adeniyi, E. T.; Groener, Y.; Schulz, F.; Krisilia, V.; Rehberg, N.; Richter, T.; Sehr, D.; Xie, H.; Simons, V. E.; Kiffe-Delf, A.-L.; Kaschani, F.; Ioerger, T. R.; Kaiser, M.; Kalscheuer, R.
10.1101/2023.07.12.548660 — microbiology — Posted on 2023-07-12
2729 Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300
Nagarajan, A.; Scoggin, K.; Gupta, J.; Aminian, M.; Adams, L. G.; Kirby, M.; threadgill, D.; Andrews-Polymenis, H. L.
10.1101/2023.07.12.548741 — microbiology — Posted on 2023-07-12
2730 Host obesity impacts genetic variation in influenza A viral populations
Knoll, M.; Honce, R.; Meliopoulos, V. A.; Schultz-Cherry, S.; Ghedin, E.; Gresham, D.
10.1101/2023.07.12.548715 — microbiology — Posted on 2023-07-12
2732 Orthogonal analysis of mitochondrial function in Parkinson's disease patients
Barnhoorn, S.; Milanese, C.; Li, T.; Dons, L.; Ghazvini, M.; Farina, S.; Sproviero, D.; Payran Gomez, C.; Mastroberardino, P. G.
10.1101/2023.07.11.548533 — neuroscience — Posted on 2023-07-12
2733 Resolving Non-identifiability Mitigates Bias in Models of Neural Tuning and Functional Coupling
Sachdeva, P.; Bak, J. H.; Livezey, J. A.; Frank, L.; Kirst, C.; Bhattacharyya, S.; Bouchard, K.
10.1101/2023.07.11.548615 — neuroscience — Posted on 2023-07-12
2740 Competition between stochastic neuropeptide signals calibrates the rate of satiation
Zhang, S. X.; Kim, A.; Madara, J. C.; Zhu, P. K.; Christenson, L. F.; Lutas, A.; Kalugin, P. N.; Jin, Y.; Paul, A.; Tian, L.; Lowell, B. B.; Andermann, M. L.
10.1101/2023.07.11.548551 — neuroscience — Posted on 2023-07-12
2741 The Integrated Stress Response effector GADD34 is repurposed by neurons to promote stimulus-induced translation
Oliveira, M. M.; Mohamed, M. S.; Elder, M. K.; Banegas-Morales, K.; Mamcarz, M.; Lu, E. H.; Golhan, E. A. N.; Navrange, N.; Chatterjee, S.; Abel, T.; Klann, E.
10.1101/2023.07.12.548606 — neuroscience — Posted on 2023-07-12
2742 Propagation path of a flowering cherry (Cerasus x yedoensis) cultivar 'Somei-Yoshino' traced by somatic mutations
Shirasawa, K.; Esumi, T.; Itai, A.; Hatakeyama, K.; Takashina, T.; Yakuwa, T.; Sumitomo, K.; Kurokura, T.; Fukai, E.; Sato, K.; Shimada, T.; Shiratake, K.; Hosokawa, M.; Monden, Y.; Kusaba, M.; Ikegami, H.; Isobe, S.
10.1101/2023.07.11.548633 — plant biology — Posted on 2023-07-12
2744 Metabolic shift toward ketosis in asocial cavefish increases social-like affinity.
Iwashita, M.; Tran, A.; Garcia, M.; Cashon, J.; Burbano, D.; Salgado, V.; Hasegawa, M.; Balmilero-Unciano, R.; Politan, K.; Wong, M.; Lee, R. W. Y.; Yoshizawa, M.
10.1101/2022.05.20.492896 — physiology — Posted on 2023-07-12
2747 Integrated Fluorescence Microscopy (iFLM) for Cryo-FIB-milling and In-situ Cryo-ET
Yang, J. E.; Vrbovska, V.; Franke, T.; Sibert, B.; Larson, M. R.; Hall, A.; Rigort, A.; Mitchels, J.; Wright, E. R.
10.1101/2023.07.11.548578 — biophysics — Posted on 2023-07-12
2755 Tutorial: guidelines for manual cell type annotation of single-cell multi-omics datasets using interactive software
Kim, Y. J.; Tarashansky, A.; Liang, K.; Urisko, M.; Dorman, L.; Borja, M.; Neff, N.; Pisco, A. O.; Granados, A.
10.1101/2023.07.11.548639 — bioinformatics — Posted on 2023-07-12
2758 Identifying Selectivity Filters in Protein Biosensor for Ligand Screening
Sahil, M.; Singh, J.; Sahu, S.; Pal, S.; Yadav, A.; Anand, R.; Mondal, J.
10.1101/2023.07.11.548514 — biochemistry — Posted on 2023-07-12
2759 Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs
Johnson, K. C.; Kilikevicius, A.; Hofman, C.; Hu, J.; Liu, Y.; Aguilar, S.; Graswich, C.; Han, Y.; Wang, T.; Wescott, J.; Brekken, R. A.; Peng, L.; Karagkounis, G.; Corey, D. R.
10.1101/2023.07.07.548119 — biochemistry — Posted on 2023-07-12
2761 Long-read Transcriptome Landscapes of Primary and Metastatic Liver Cancers at Transcript Resolution
Chen, Z.; Shi, Q.; Zhao, Y.; Xu, M.; Liu, Y.; Li, X.; Liu, L.; Sun, M.; Wu, X.; Shao, Z.; Xu, Y.; Wang, L.; He, X.
10.1101/2023.07.11.548526 — genomics — Posted on 2023-07-12
2766 Epigenetic variations are accompanying landmarks of freshwater adaptation in threespine sticklebacks
Golden, A.; Starshin, A.; Mazur, A.; Mugue, N.; Kaplun, D.; Artemov, A.; Khrameeva, E.; Prokhortchouk, E.
10.1101/2022.08.22.504457 — evolutionary biology — Posted on 2023-07-12
2767 Understanding woody plant encroachment: a plant functional trait approach
de Jonge, I. K.; Olff, H.; Mayemba, E. P.; Berger, S. J.; Veldhuis, M. P.
10.1101/2023.07.11.548581 — ecology — Posted on 2023-07-12
2772 Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
Smirnova, A. M.; Hronova, V.; Gunisova, S.; Mohammad, M. P.; Petrackova, D.; Halada, P.; Rendelman, J.; Coufal, S.; Herrmannova, A.; Beznoskova, P.; Jendruchova, K.; Hatzoglou, M.; Vogel, C.; Valasek, L. S.
10.1101/2023.07.12.548609 — molecular biology — Posted on 2023-07-12
2774 Cryo-electron tomography of enterovirus cell entry and endosome escape
Ishemgulova, A.; Mukhamedova, L.; Trebichalska, Z.; Rajecka, V.; Payne, P.; Smerdova, L.; Moravcova, J.; Hrebik, D.; Buchta, D.; Skubnik, K.; Fuzik, T.; Vanacova, S.; Novacek, J.; Plevka, P.
10.1101/2023.07.12.548671 — microbiology — Posted on 2023-07-12
2775 Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen
Khan, F.; Muller, T. R.; Kasmapour, B.; Durand, M. A. Y.; Eiz-Vesper, B.; Einem, J. v.; Busch, D. H.; Cicin-Sain, L.
10.1101/2023.07.11.548645 — immunology — Posted on 2023-07-12
2777 Predictions and errors are distinctly represented across V1 layers
Thomas, E. R.; Haarsma, J.; Nicholson, J.; Yon, D.; Kok, P.; Press, C.
10.1101/2023.07.11.548408 — neuroscience — Posted on 2023-07-12
2778 Moderate intensity aerobic exercise in 6-OHDA-lesioned rats alleviates established motor deficits and reduces neurofilament light and glial fibrillary acidic protein serum levels without increased striatal dopamine or tyrosine hydroxylase protein
Kasanga, E. A.; Soto, I.; Centner, A.; McManus, R.; Shifflet, M. K.; Navarrete, W.; Han, Y.; Lisk, J.; Wheeler, K.; Mhatre-Winters, I.; Richardson, J. R.; Bishop, C.; Nejtek, V. A.; Salvatore, M. F.
10.1101/2023.07.11.548638 — neuroscience — Posted on 2023-07-12
2782 Competition between stochastic neuropeptide signals calibrates the rate of satiation
Zhang, S. X.; Kim, A.; Madara, J. C.; Zhu, P. K.; Christenson, L. F.; Lutas, A.; Kalugin, P. N.; Jin, Y.; Paul, A.; Tian, L.; Lowell, B. B.; Andermann, M. L.
10.1101/2023.07.11.548551 — neuroscience — Posted on 2023-07-12
2785 Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin (ELGA) reveal functional IP3 receptors
Calvo, B.; Torres-Vidal, P.; Delrio, A.; Rodriguez, C.; Aulestia, F.; Rojo-Ruiz, J.; Garcia-Sancho, J.; Patel, S.; Alonso, M. T.
10.1101/2023.07.11.547422 — physiology — Posted on 2023-07-12
2786 Chimeric oncolytic adenovirus evades neutralizing antibodies from human patients and exhibits enhanced anti-glioma efficacy in immunized mice
Shin, D. H.; Jiang, H.; Gillard, A. G.; Kim, D. K.; Fan, X.; Singh, S. K.; Nguyen, T. T.; Sohoni, S. S.; Lopez-Rivas, A. R.; Parthasarathy, A.; Ene, C. I.; Gumin, J.; Lang, F. F.; Alonso, M. M.; Gomez-Manzano, C.; Fueyo, J.
10.1101/2023.07.11.548552 — cancer biology — Posted on 2023-07-12
2787 Clinical proteomics reveals vulnerabilities in non-invasive breast ductal carcinoma and drives personalized treatment strategies.
Mitsa, G.; Florianova, L.; Lafleur, J.; Aguilar-Mahecha, A.; Zahedi, R. P.; Del Rincon, S. V.; Basik, M.; Borchers, C. H.; Batist, G.
10.1101/2023.07.11.548580 — cancer biology — Posted on 2023-07-12
2789 Simulations of sequence evolution: how (un)realistic they really are and why
Trost, J.; Haag, J.; Hoehler, D.; Nesterenko, L.; Jacob, L.; Stamatakis, A.; Boussau, B.
10.1101/2023.07.11.548509 — bioinformatics — Posted on 2023-07-12
2791 Acidic nanoparticles restore lysosomal acidification and rescue metabolic dysfunction in pancreatic β-cells under lipotoxic condition
Lo, C. H.; O'Connor, L. M.; Loi, G. W. Z.; Saipuljumri, E. N.; Indajang, J.; Lopes, K. M.; Shirihai, O. S.; Grinstaff, M. W.; Zeng, J.
10.1101/2023.07.11.548395 — bioengineering — Posted on 2023-07-12
2792 Quantification of glutathione with high throughput live-cell imaging
Qi, X.; Chen, J.; Jiang, X.; Lu, D.; Yu, X.; Lin, H.; Monroy, E. Y.; Wang, M. C.; Wang, J.
10.1101/2023.07.11.548586 — biochemistry — Posted on 2023-07-12
2793 High quality genome assembly and annotation (v1) of the eukaryotic terrestrial microalga Coccomyxa viridis SAG 216-4
Kraege, A.; Chavarro-Carrero, E.; Guiglielmoni, N.; Schnell, E.; Kirangwa, J.; Heilmann-Heimbach, S.; Becker, K.; Kohrer, K.; WGGC Team, ; DeRGA Community, ; Schiffer, P.; Thomma, B. P.; Rovenich, H.
10.1101/2023.07.11.548521 — genomics — Posted on 2023-07-12
2797 ATUM-Tomo: A multi-scale approach to cellular ultrastructure by combined volume scanning electron microscopy and electron tomography
Kislinger, G.; Fabig, G.; Wehn, A. C.; Rodriguez, L.; Jiang, H.; Niemann, C.; Klymchenko, A. S.; Plesnila, N.; Misgeld, T.; Mueller-Reichert, T.; Khalin, I.; Schifferer, M.
10.1101/2023.07.12.547497 — neuroscience — Posted on 2023-07-12
2799 The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2
Pekar, J. E.; Lytras, S.; Ghafari, M.; Magee, A. F.; Parker, E.; Havens, J. L.; Katzourakis, A.; Vasylyeva, T. I.; Suchard, M. A.; Hughes, A. C.; Hughes, J.; Robertson, D. L.; Dellicour, S.; Worobey, M.; Wertheim, J. O.; Lemey, P.
10.1101/2023.07.12.548617 — evolutionary biology — Posted on 2023-07-12
2804 Core enhancers of the 3'RR optimize IgH nuclear position and loop conformation for oriented CSR
Bruzeau, C.; Pollet, J.; Thomas, M.; Ba, Z.; Roulois, D.; PINAUD, E.; Le Noir, S.
10.1101/2023.07.11.548507 — immunology — Posted on 2023-07-12
2805 Evolution of connectivity architecture in the Drosophila mushroom body
Ellis, K. E.; Bervoets, S.; Smihula, H.; Ganguly, I.; Vigato, E.; Auer, T. O.; Benton, R.; Litwin Kumar, A.; Caron, S. J. C.
10.1101/2023.02.10.528036 — neuroscience — Posted on 2023-07-12
2807 Biomimetic multi-channel microstimulation of somatosensory cortex conveys high resolution force feedback for bionic hands
Greenspon, C. M.; Valle, G.; Hobbs, T.; Verbaarschot, C.; Callier, T.; Schelchkova, N.; Sobinov, A.; Jordan, P.; Weiss, J. M.; Fitzgerald, E.; Prasad, D.; van Driesche, A.; Lee, R.; Satzer, D.; Gonzalez-Martinez, J.; Warnke, P.; Miller, L. E.; Boninger, M.; Collinger, J.; Gaunt, R.; Hatsopoulos, N.; Downey, J. E.; Bensmaia, S. J.
10.1101/2023.02.18.528972 — neuroscience — Posted on 2023-07-12
2808 Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Mastwal, S.; Li, X.; Stowell, R. D.; Manion, M.; Zhang, W.; Kim, N.-S.; Yoon, K.-J.; Song, H.; Ming, G.-L.; Wang, K. H.
10.1101/2023.02.03.526987 — neuroscience — Posted on 2023-07-12
2809 Expression of cell-wall related genes is highly variable and correlates with sepal morphology
Hartasanchez, D. A.; Kiss, A. K.; Battu, V.; Soraru, C.; Delgado Vaquera, A.; Massinon, F.; Braso-Vives, M.; Mollier, C.; Martin-Magnette, M.-L.; Boudaoud, A.; Moneger, F.
10.1101/2022.04.26.489498 — plant biology — Posted on 2023-07-12
2811 fastlin: an ultra-fast program for Mycobacterium tuberculosis complex lineage typing
Derelle, R.; Lees, J.; Phelan, J.; Lalvani, A.; Arinaminpathy, N.; Chindelevitch, L.
10.1101/2023.07.11.548517 — bioinformatics — Posted on 2023-07-12
2813 Epitope Engineered Human Haematopoietic Stem Cells are Shielded from CD123-targeted Immunotherapy
Marone, R.; Landmann, E.; Devaux, A.; Lepore, R.; Seyres, D.; Zuin, J.; Burgold, T.; Engdahl, C.; Capoferri, G.; DellAglio, A.; Larrue, C.; Simonetta, F.; Rositzka, J.; Rhiel, M.; Andrieux, G.; Gallagher, D.; Schroeder, M.; Wiederkehr, A.; Sinopoli, A.; Do Sacramento, V.; Haydn, A.; Garcia-Prat, L.; Divsalar, C.; Camus, A.; Xu, L.; Bordoli, L.; Schwede, T.; Porteus, M.; Tamburini Bonnefoy, J.; Corn, J. E.; Cathomen, T.; Cornu, T. I.; Urlinger, S.; Jeker, L. T.
10.1101/2023.07.11.547391 — bioengineering — Posted on 2023-07-12
2814 Specialized mesenteric lymphatic capillaries by-pass the mesenteric lymph node chain to transport peritoneal antigens directly into mediastinal lymph nodes.
Redder, E.; Kirschnick, N.; Fang, S.; Kuhlmann, M.; Gonzalez-Loyola, A.; Wyss, T.; Stehling, M.; Adams, R. H.; Petrova, T. V.; Alitalo, K. K.; Rot, A.; Kiefer, F.
10.1101/2023.07.11.548304 — developmental biology — Posted on 2023-07-12
2815 Blood pressure lowering enhances cerebrospinal fluid efflux primarily via the lymphatic vasculature
Jukkola, J.; Kaakinen, M.; Singh, A.; Moradi, S.; Ferdinando, H.; Myllyla, T.; Kiviniemi, V.; Eklund, L.
10.1101/2023.07.11.548482 — neuroscience — Posted on 2023-07-12
2816 The pelvic organs receive no parasympathetic innervation
Sivori, M.; Dempsey, B.; Chettouh, Z.; Boismoreau, F.; Ayerdi, M.; Eymael, A.; Baulande, S.; Lameiras, S.; Coulpier, F.; Delattre, O.; Rohrer, H.; Mirabeau, O.; Brunet, J.-F.
10.1101/2023.07.11.548500 — neuroscience — Posted on 2023-07-12
2818 Remodelling of cytoskeleton and plasma membrane proteins contributes to drought sensitivity of Arabidopsis rhd2 mutant
Takac, T.; Kubenova, L.; Samajova, O.; Dvorak, P.; Haberland, J.; Bundschuh, S.; Tomancak, P.; Ovecka, M.; Samaj, J.
10.1101/2023.07.11.548511 — plant biology — Posted on 2023-07-12
2819 Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable Interaction with CTBP2
Pastoors, D.; Havermans, M.; Mulet-Lazaro, R.; Brian, D.; Noort, W.; Grasel, J.; Hoogenboezem, R.; Smeenk, L.; Demmers, J. A.; Enver, T.; Groen, R. W.; Bindels, E.; Delwel, R.
10.1101/2023.07.11.548358 — cancer biology — Posted on 2023-07-12
2820 Physics-informed deep generative learning for quantitative assessment of the retina
Brown, E.; Guy, A.; Holroyd, N.; Sweeney, P.; Gourmet, L.; Coleman, H.; Walsh, C.; Shipley, R.; Rajendram, R.; Walker-Samuel, S.
10.1101/2023.07.10.548427 — biophysics — Posted on 2023-07-12
2821 Salmonella enterica serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage
Kumwenda, B.; Canals, R.; Predeus, A. V.; Zhu, X.; Kroeger, C.; Pulford, C.; Wenner, N.; Lacharme-Lora, L.; Owen, S. V.; Li, Y.; Everett, D. B.; Hokamp, K.; Heyderman, R. S.; Ashton, P. M.; Gordon, M. A.; Msefula, C. L.; Hinton, J. C. D.
10.1101/2023.07.11.548493 — bioinformatics — Posted on 2023-07-12
2823 Study of the seasonal life cycle of Lutzomyia longiflocosa (Diptera: Psychodidae) under semi-controlled conditions in the department of Huila, Colombia
Vargas Durango, J. A.; Mestre Carillo, G. I.; Santamaria Herreno, E.; Beltran Ruiz, M. A.; Zapata Lesmes, A. C.; Munoz Ortiz, A. G.; ESCOBAR CASTRO, J. E.
10.1101/2023.07.11.548498 — zoology — Posted on 2023-07-12
2825 Transcriptome profiles of T.b. rhodesiense parasites in Malawi reveal focus specific gene expression Profiles associated with pathology
Nambala, P.; Noyes, H.; Namulondo, J.; Nyangiri, O.; Alibu, P.; Barbara, N.; MacLeod, A.; Matovu, E.; Musaya, J.; Mulindwa, J.
10.1101/2023.07.11.548495 — genomics — Posted on 2023-07-12
2829 Ignorance is bliss: effects of noise and metaboliccost on cortical task representations
Stroud, J. P.; Wojcik, M. J.; Jensen, K. T.; Kusunoki, M.; Kadohisa, M.; Duncan, J.; Stokes, M. G.; Lengyel, M.
10.1101/2023.07.11.548492 — neuroscience — Posted on 2023-07-12
2832 Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes
Petitjean, K.; Verres, Y.; Bristeau, S.; Ribault, C.; Aninat, C.; Olivier, C.; Leroyer, P.; Ropert, M.; Loreal, O.; Herault, O.; Amalric, L.; Baran, N.; Fromenty, B.; Corlu, A.; Loyer, P.
10.1101/2023.07.11.548490 — pharmacology and toxicology — Posted on 2023-07-12
2833 The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection
Jones, K.; Nguyen, D. M.; Poveda, C.; Pollet, J.; Gusovsky, F.; Bottazzi, M. E.; Hotez, P. J.
10.1101/2023.07.11.548497 — pathology — Posted on 2023-07-12
2834 Global diversity of enterococci and description of 18 novel species
Schwartzman, J. A.; Lebreton, F.; Salamzade, R.; Martin, M. J.; Schaufler, K.; Urhan, A.; Abeel, T.; Camargo, I. L. B. C.; Sgardioli, B. F.; Prichula, J.; Frazzon, A. P. G.; Van Tyne, D.; Treinish, G.; Innis, C. J.; Wagenaar, J. A.; Whipple, R. M.; Manson, A. L.; Earl, A. M.; Gilmore, M. S.
10.1101/2023.05.18.540996 — microbiology — Posted on 2023-07-12
2836 Ligand bias underlies differential signaling of multiple FGFs via FGFR1
Karl, K. A.; Hristova, K.; Krejci, P.; Del Piccolo, N.; Light, T.; Roy, T.; Dudeja, P.; Ursachi, V.-C.; Fafilek, B.
10.1101/2022.01.06.475273 — biophysics — Posted on 2023-07-12
2837 Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats
Ishiwari, K.; King, C. P.; Martin, C. D.; Tripi, J. A.; George, A. M.; Lamparelli, A. C.; Chitre, A.; Polesskaya, O.; Richards, J. B.; Solberg Woods, L. C.; Gancarz, A.; Palmer, A. A.; Dietz, D. M.; Mitchell, S. H.; Meyer, P. J.
10.1101/2023.06.30.547228 — animal behavior and cognition — Posted on 2023-07-12
2838 Common evolutionary origins of the bacterial glycyl tRNA synthetase and alanyl tRNA synthetase
Alvarez-Carreno, C.; Arciniega, M.; Ribas de Pouplana, L.; Petrov, A. S.; Hernandez-Gonzalez, A.; Valencia-Sanchez, M. I.; Williams, L. D.; Torres-Larios, A.
10.1101/2023.05.29.542759 — evolutionary biology — Posted on 2023-07-12
2842 Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans
Medwig-Kinney, T. N.; Kinney, B. A.; Martinez, M. A. Q.; Yee, C.; Sirota, S. S.; Mullarkey, A. A.; Somineni, N.; Hippler, J.; Zhang, W.; Shen, K.; Hammell, C. M.; Pani, A. M.; Matus, D. Q.
10.1101/2022.09.30.510381 — developmental biology — Posted on 2023-07-12
2843 An atlas of spider development at single-cell resolution provides new insights into arthropod embryogenesis
Leite, D. J.; Schoenauer, A.; Blakeley, G.; Harper, A.; Garcia-Castro, H.; Baudouin-Gonzalez, L.; Wang, R.; Sarkis, N.; Nikola, A. G.; Koka, V. S. P.; Kenny, N. J.; Turetzek, N.; Pechmann, M.; Solana, J.; McGregor, A. P.
10.1101/2022.06.09.495456 — developmental biology — Posted on 2023-07-12
2844 Human neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
Krontira, A. C.; Cruceanu, C.; Dony, L.; Kyrousi, C.; Link, M. H.; Kappelmann, N.; Poehlchen, D.; Raimundo, C.; Penner-Goeke, S.; Schowe, A.; Czamara, D.; Lahti-Pulkkinen, M.; Sammallahti, S.; Wolford, E.; Heinonen, K.; Roeh, S.; Sportelli, V.; Woelfel, B.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Raikkonen, K.; Labeur, M.; Cappello, S.; Binder, E. B.
10.1101/2022.08.21.504700 — neuroscience — Posted on 2023-07-12
2845 A guide to the in vitro reconstitution of Cdc42 GTPase activity and its regulation
Tschirpke, S.; van Opstal, F.; van der Valk, R.; Daalman, W. K.-G.; Laan, L.
10.1101/2023.04.24.538075 — biochemistry — Posted on 2023-07-12
2846 Adaptive introgression of a visual preference gene
Rossi, M.; Hausmann, A. H.; Alcami, P.; Moest, M. H.; Wright, D. S.; Kuo, C.-Y.; Lozano, D.; Maulana, A.; Melo-Florez, L.; Rueda-Munoz, G.; McMahon, S.; Linares, M.; McMillan, W. O.; Pardo-Diaz, C.; Salazar, C.; Merrill, R. M.
10.1101/2023.07.12.548653 — evolutionary biology — Posted on 2023-07-12
2847 The impact of sex on gene expression in the brain of schizophrenic patients: a systematic review and meta-analysis of transcriptomic studies
Carceller, H.; Hidalgo, M. R.; Anton-Bernat, G.; Escarti, M. J.; Nacher, J.; de la Iglesia-Vaya, M.; Garcia-Garcia, F.
10.1101/2023.02.13.528356 — molecular biology — Posted on 2023-07-12
2855 RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration
Matsuo, K.; Asamitsu, S.; Maeda, K.; Kawakubo, K.; Komiya, G.; Kudo, K.; Sakai, Y.; Hori, K.; Ikenoshita, S.; Usuki, S.; Funahashi, S.; Kawata, Y.; Mizobata, T.; Shioda, N.; Yabuki, Y.
10.1101/2023.07.10.548322 — molecular biology — Posted on 2023-07-12
2857 Reverse Engineering DNA Origami Nanostructure Designs from Raw Scaffold and Staple Sequence Lists
Shirt-Ediss, B.; Connolly, J.; Elezgaray, J.; Torelli, E.; Navarro, S. A.; Bacardit, J.; Krasnogor, N.
10.1101/2023.05.03.539261 — bioinformatics — Posted on 2023-07-12
2859 Exoribonuclease RNase R protects Antarctic Pseudomonas syringae Lz4W from DNA damage and oxidative stress
Mittal, P.; Sipani, R.; Pandiyan, A.; Sulthana, S.; Sinha, A. K.; Hussain, A.; Ray, M. K.; Pavankumar, T. L.
10.1101/2023.06.01.543265 — microbiology — Posted on 2023-07-12
2861 Precise Spatial Tuning of Visually Driven Alpha Oscillations in Human Visual Cortex
Yuasa, K.; Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Ramsey, N.; Petridou, N.; Winawer, J.
10.1101/2023.02.11.528137 — neuroscience — Posted on 2023-07-12
2864 High-throughput 3D imaging flow cytometry of adherent 3D cell cultures
Yamashita, M.; Tamamitsu, M.; Kirisako, H.; Goda, Y.; Chen, X.; Hattori, K.; Ota, S.
10.1101/2023.07.10.548361 — bioengineering — Posted on 2023-07-12
2866 Experimental drought reduces the productivity and stability of a recovering calcareous grassland
Jackson, J.; Middleton, S. L.; Lawson, C. S.; Jardine, E.; Hawes, N.; Maseyk, K.; Salguero-Gomez, R.; Hector, A.
10.1101/2023.07.11.548537 — ecology — Posted on 2023-07-12
2868 The Hypoxia-regulated Ectonucleotidase CD73 is a Host Determinant of HIV Latency
Sperber, H. S.; Raymond, K. A.; Bouzidi, M. S.; Ma, T.; Valdebenito, S.; Eugenin, E.; Roan, N. R.; Deeks, S. G.; Winning, S.; Fandrey, J.; Schwarzer, R.; Pillai, S. K.
10.1101/2022.08.03.502655 — microbiology — Posted on 2023-07-12
2871 Bacterial sepsis triggers stronger transcriptomic responses in larger primates
McMinds, R.; Jiang, R. H.; Adapa, S. R.; Cornelius Ruhs, E.; Munds, R. A.; Leiding, J. W.; Downs, C.; Martin, L. B.
10.1101/2023.07.11.548565 — evolutionary biology — Posted on 2023-07-11
2873 A workflow combining single-cell CRISPRi screening and a supervised autoencoder neural network to detect subtle transcriptomic perturbations induced by lncRNA Knock-Down
Truchi, M.; Lacoux, C.; Gille, C.; Fassy, J.; Magnone, V.; Lopez-Goncalvez, R.; Girard-Riboulleau, C.; Manosalva-Pena, I.; Gautier-Isola, M.; Spicuglia, S.; Vassaux, G.; Rezzonico, R.; Barlaud, M.; Mari, B.
10.1101/2023.07.11.548494 — bioinformatics — Posted on 2023-07-11
2876 Enhanced long-term memory and increased mushroom body plasticity in Heliconius butterflies
Young, F. J.; Alcalde, A.; Melo-Florez, L.; Couto, A.; Foley, J.; Monllor, M.; McMillan, W. O.; Montgomery, S. H.
10.1101/2023.07.11.548546 — animal behavior and cognition — Posted on 2023-07-11
2878 Patterns of recombination in snakes reveal a tug of war between PRDM9 and promoter-like features
Hoge, C. R.; de Manuel, M.; Mahgoub, M.; Okami, N.; Fuller, Z. L.; Banerjee, S.; Baker, Z.; Mcnulty, M.; Andolfatto, P.; Macfarlan, T. S.; Schumer, M.; Tzika, A. C.; Przeworski, M.
10.1101/2023.07.11.548536 — evolutionary biology — Posted on 2023-07-11
2882 Mitochondrial proteostasis mediated by CRL5Ozz and Alix maintains skeletal muscle function
Campos, Y.; Rodriguez-Enriquez, R.; Palacios, G.; Van de Vlekkert, D.; Qiu, X.; Weesner, J.; Gomero, E.; Demmers, J.; Bertorini, T.; Opferman, J. T.; Grosveld, G. T.; d'Azzo, A.
10.1101/2023.07.11.548601 — cell biology — Posted on 2023-07-11
2883 RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration
Matsuo, K.; Asamitsu, S.; Maeda, K.; Kawakubo, K.; Komiya, G.; Kudo, K.; Sakai, Y.; Hori, K.; Ikenoshita, S.; Usuki, S.; Funahashi, S.; Kawata, Y.; Mizobata, T.; Shioda, N.; Yabuki, Y.
10.1101/2023.07.10.548322 — molecular biology — Posted on 2023-07-11
2884 A flexible high-throughput cultivation protocol to assess the response of individuals' gut microbiota to diet-, drug-, and host-related factors
Zund, J. N.; Pluss, S.; Mujezinovic, D.; Menzi, C.; von Bieberstein, P. R.; de Wouters, T.; Lacroix, C.; Leventhal, G. E.; Pugin, B.
10.1101/2023.07.11.548549 — microbiology — Posted on 2023-07-11
2885 Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spineformation
Weesner, J. A.; Annunziata, I.; van de Vlekkert, D.; Robinson, C. G.; Campos, Y.; Mishra, A.; Fremuth, L. E.; Gomero, E.; Hu, H.; d'Azzo, A.
10.1101/2023.07.10.548446 — neuroscience — Posted on 2023-07-11
2888 Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with MAPT Mutations
Bertucci, T.; Bowles, K. R.; Lotz, S.; Qi, L.; Stevens, K.; Goderie, S. K.; Borden, S.; Oja, L.; Lane, K.; Lotz, R.; Lotz, H.; Chowdhury, R.; Joy, S.; Arduini, B. L.; Butler, D. C.; Miller, M.; Baron, H.; Sandhof, C. A.; Silva, M. C.; Haggarty, S. J.; Karch, C. M.; Geschwind, D. H.; Goate, A. M.; Temple, S.
10.1101/2023.07.11.548571 — neuroscience — Posted on 2023-07-11
2890 Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex
Murphy, K. E.; Duncan, B. W.; Sperringer, J. E.; Zhang, E. Y.; Haberman, V. A.; Wyatt, E. V.; Maness, P. F.
10.1101/2023.07.11.548527 — neuroscience — Posted on 2023-07-11
2892 Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development
Yuan, T.; Wang, Y.; Jin, Y.; Xu, S.; Zhang, H.; Chen, Q.; Li, N.; Ma, X.; Song, H.; Peng, C.; Yang, H.; Geng, Z.; Dong, J.; Duan, G.; Sun, Q.; Yang, Y.; Yang, F.; Huang, Z.
10.1101/2023.03.16.532982 — neuroscience — Posted on 2023-07-11
2897 Proteome-wide copy-number estimation from transcriptomics
Sweatt, A. J.; Griffiths, C. D.; Paudel, B. B.; Janes, K. A.
10.1101/2023.07.10.548432 — systems biology — Posted on 2023-07-11
2898 xTrimoPGLM: Unified 100B-Scale Pre-trained Transformer for Deciphering the Language of Protein
Chen, B.; Cheng, X.; Gengyang, L.-a.; Li, S.; Zeng, X.; Wang, B.; Jing, G.; Liu, C.; Zeng, A.; Dong, Y.; Tang, J.; Song, L.
10.1101/2023.07.05.547496 — synthetic biology — Posted on 2023-07-11
2900 NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy
Choudhury, A.; Cady, M. A.; Lucas, C.-H. G.; Najem, H.; Phillips, J. J.; Palikuqi, B.; Zakimi, N.; Joseph, T.; Birreuta, J. O.; Chen, W. C.; Bush, N. A. O.; Hervey-Jumper, S. L.; Klein, O. D.; Toedebusch, C. M.; Horbinski, C. M.; Magill, S. T.; Bhaduri, A.; Perry, A.; Dickinson, P. J.; Heimberger, A. B.; Ashworth, A.; Crouch, E. E.; Raleigh, D. R.
10.1101/2023.07.10.548456 — cancer biology — Posted on 2023-07-11
2902 MICA: A multi-omics method to predict gene regulatory networks in early human embryos
Alanis-Lobato, G.; Bartlett, T. E.; Huang, Q.; Simon, C.; McCarthy, A.; Elder, K.; Snell, P.; Christie, L.; Niakan, K.
10.1101/2023.02.03.527081 — developmental biology — Posted on 2023-07-11
2903 Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix
Warner, H.; Franciosa, G.; van der Borg, G.; Faas, F.; Koenig, C.; de Boer, R.; Classens, R.; Maassen, S.; Baranov, M.; Mahajan, S.; Dabral, D. D.; Coenen, B.; Bianchi, F.; van Hilten, N.; Risselada, H. J.; Roos, W. H.; Olsen, J.; Querol Cano, L.; van den Bogaart, G. V.
10.1101/2023.07.10.548429 — cell biology — Posted on 2023-07-11
2905 Comammox bacterial preference for urea influences its interactions with aerobic nitrifiers.
Vilardi, K. J.; Johnston, J.; Dai, Z.; Cotto, I.; Tuttle, E.; Patterson, A.; Stubbins, A.; Pieper, K.; Pinto, A.
10.1101/2023.07.11.548560 — microbiology — Posted on 2023-07-11
2907 Arbuscular mycorrhiza convey significant plant carbon to a diverse hyphosphere microbial food web and mineral-associated organic matter
Kakouridis, A.; Yuan, M.; Nuccio, E. E.; Hagen, J. A.; Fossum, C. A.; Moore, M. L.; Estera-Molina, K.; Nico, P. S.; Weber, P. K.; Pett-Ridge, J.; Firestone, M. K.
10.1101/2023.07.11.548626 — microbiology — Posted on 2023-07-11
2908 Highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b in domestic ducks, Indonesia, 2022
Wibawa, H.; Wibowo, P. E.; Supriyadi, A.; Lestari, ; Silaban, J.; Fuadi, A. A.; Fiqri, A. J.; Handayani, R. W.; Irianingsih, S. H.; Fahmia, Z.; Mulyawan, H.; Idris, S.; Zainuddin, N.
10.1101/2023.07.10.548369 — microbiology — Posted on 2023-07-11
2909 The Role of Attention in Immersion: The Two-Competitor Model
Strauss, D. J.; Francis, A. L.; Vibell, J.; Corona-Strauss, F. I.
10.1101/2023.07.10.548435 — neuroscience — Posted on 2023-07-11
2910 Neuronal wiring diagram of an adult brain
Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. E.; Lin, A.; Costa, M.; Eichler, K.; Yin, Y.; Silversmith, W.; Schneider-Mizell, C.; Jordan, C. S.; Brittain, D.; Halageri, A.; Kuehner, K.; Ogedengbe, O.; Morey, R.; Gager, J.; Kruk, K.; Perlman, E.; Yang, R.; Deutsch, D.; Bland, D.; Sorek, M.; Lu, R.; Macrina, T.; Lee, K.; Bae, J. A.; Mu, S.; Nehoran, B.; Mitchell, E.; Popovych, S.; Wu, J.; Jia, Z.; Castro, M.; Kemnitz, N.; Ih, D.; Bates, A. S.; Eckstein, N.; Funke, J.; Collman, F.; Bock, D. D.; Jefferis, G. S. X. E.; Seung, H. S.; Murthy, M.; the FlyWire Co
10.1101/2023.06.27.546656 — neuroscience — Posted on 2023-07-11
2912 Efficient PCR-based gene targeting in isolates of the non-conventional yeast Debaryomyces hansenii
Alhajouj, S.; Turkolmez, S.; Abalkhail, T.; Alwan, Z. H. O.; Gilmour, D. J.; Mitchell, P. J.; Hettema, E. H.
10.1101/2023.07.11.548570 — synthetic biology — Posted on 2023-07-11
2913 Handling difficult cryo-ET samples: A study with primary neurons from Drosophila melanogaster
Kim, J. Y.; Yang, J. E.; Mitchell, J. W.; English, L. A.; Yang, S. Z.; Tenpas, T.; Dent, E. W.; Wildonger, J.; Wright, E. R.
10.1101/2023.07.10.548468 — biophysics — Posted on 2023-07-11
2918 High-throughput 3D imaging flow cytometry of adherent 3D cell cultures
Yamashita, M.; Tamamitsu, M.; Kirisako, H.; Goda, Y.; Chen, X.; Hattori, K.; Ota, S.
10.1101/2023.07.10.548361 — bioengineering — Posted on 2023-07-11
2920 The Hidden Biocatalytic Potential of the Old Yellow Enzyme Family
White, D. W.; Iamurri, S.; Keshavarz-Joud, P.; Blue, T.; Copp, J. N.; Lutz, S.
10.1101/2023.07.10.548207 — biochemistry — Posted on 2023-07-11
2923 Mapping the dynamics of epigenetic adaptation
Larkin, A.; Kunze, C.; Seman, M.; Levashkevich, A.; Curran, J.; Ragunathan, K.; Khalil, A. S.
10.1101/2023.07.10.548368 — genetics — Posted on 2023-07-11
2927 Experimental drought reduces the productivity and stability of a recovering calcareous grassland
Jackson, J.; Middleton, S. L.; Lawson, C. S.; Jardine, E.; Maseyk, K.; Salguero-Gomez, R.; Hector, A.
10.1101/2023.07.11.548537 — ecology — Posted on 2023-07-11
2931 The distribution of fitness effects of plasmid pOXA-48 in clinical enterobacteria
Fernandez-Calvet, A.; Toribio-Celestino, L.; Alonso-del Valle, A.; Sastre-Dominguez, J.; Valdes-Chiara, P.; San Millan, A.; DelaFuente, J.
10.1101/2023.07.11.548518 — microbiology — Posted on 2023-07-11
2933 A Versatile and Open Source One- and Two-Photon Light-Sheet Microscope Design
Panier, T.; Migault, G.; Hubert, A.; Trentesaux, H.; Beaudou, B.; Debregeas, G.; Bormuth, V.
10.1101/2023.07.10.548107 — neuroscience — Posted on 2023-07-11
2935 Sustained hippocampal theta-oscillations reflect experience-dependent learning in bidirectional temporal-order memory retrieval
Jiang, H.; Cai, J.; Santos-Pata, D.; Shi, L.; Zhu, X.; Tong, J.; Cai, Y.; Li, C.; Wang, R.; Yin, J.; Zhang, S.; Kwok, S. C.
10.1101/2023.07.10.548388 — neuroscience — Posted on 2023-07-11
2936 MicroRNA-375 is induced during astrocyte-to-neuron reprogramming and promotes survival of reprogrammed neurons when overexpressed
Chen, X.; Sokirniy, I.; Wang, X.; Jiang, M.; Mseis-Jackson, N.; Williams, C.; Mayes, K.; Jiang, N.; Puls, B.; Du, Q.; Shi, Y.; Li, H.
10.1101/2023.07.10.548401 — neuroscience — Posted on 2023-07-11
2940 MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention
Qiu, B.; Lawan, A.; Xirouchaki, C. E.; Yi, J.-S.; Robert, M.; Zhang, L.; Brown, W.; Fernandez-Hernando, C.; Yang, X.; Bennett, A. M.
10.1101/2023.07.10.548263 — physiology — Posted on 2023-07-11
2941 Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis
Kim, D.; Horimatsu, T.; Ogbi, M.; Goo, B.; Shi, H.; Veerapaneni, P.; Chouhaita, R.; Moses, M.; Prasad, R.; Benson, T. W.; Harb, R.; Aboud, G.; Sellers, H.; Haigh, S.; Fulton, D. J. R.; Csanyi, G.; Huo, Y.; Long, X.; Coffey, P.; Lee, R.; Guha, A.; Zeldin, D.; Hwang, S. H.; Hammock, B.; Weintraub, N. L.; Kim, H. W.
10.1101/2023.07.10.548127 — pharmacology and toxicology — Posted on 2023-07-11
2942 Noncanonical TRAIL Signaling Promotes Myeloid-Derived Suppressor Cell Abundance and Tumor Progression in Cholangiocarcinoma
Loeuillard, E.; Li, B.; Stumpf, H. E.; Yang, J.; Willhite, J. R.; Tomlinson, J. L.; Wang, J.; Rakhshan Rohakhtar, F.; Simon, V. A.; Graham, R. P.; Smoot, R. L.; Dong, H.; Ilyas, S. I.
10.1101/2023.05.24.541931 — cancer biology — Posted on 2023-07-11
2946 Petascale Homology Search for Structure Prediction
Lee, S.; Kim, G.; Levy Karin, E.; Mirdita, M.; Park, S.; Chikhi, R.; Babaian, A.; Kryshtafovych, A.; Steinegger, M.
10.1101/2023.07.10.548308 — bioinformatics — Posted on 2023-07-11
2947 Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment
Diaz-Gay, M.; Vangara, R.; Barnes, M.; Wang, X.; Islam, S. M. A.; Vermes, I.; Narasimman, N. B.; Yang, T.; Jiang, Z.; Moody, S.; Senkin, S.; Brennan, P.; Stratton, M.; Alexandrov, L. B.
10.1101/2023.07.10.548264 — bioinformatics — Posted on 2023-07-11
2949 3D bioprinting directly affects proteomic signature and myogenic maturation in muscle pericytes-derived human myo-substitute.
Reggio, A.; Fuoco, C.; De Paolis, F.; Testa, S.; Celikkin, N.; Bernardini, S.; Baldi, J.; Biagini, R.; Seliktar, D.; Cirillo, C.; Grumati, P.; Cannata, S.; Costantini, M.; Gargioli, C.
10.1101/2023.07.10.548389 — bioengineering — Posted on 2023-07-11
2955 Structural rather than catalytic role for mitochondrial respiratory chain supercomplexes
Brischigliaro, M.; Cabrera-Orefice, A.; Arnold, S.; Viscomi, C.; Zeviani, M.; Fernandez-Vizarra, E.
10.1101/2023.04.19.537447 — biochemistry — Posted on 2023-07-11
2957 Genomic Surveillance of SARS-CoV-2 Using Long-Range PCR Primers
Kandel, S.; Hartzell, S. L.; Ingold, A. K.; Turner, G. A.; Kennedy, J. L.; Ussery, D. W.
10.1101/2023.07.10.548464 — genomics — Posted on 2023-07-11
2959 The complete sequence of a human Y chromosome
Rhie, A.; Nurk, S.; Cechova, M.; Hoyt, S. J.; Taylor, D. J.; Altemose, N.; Hook, P. W.; Koren, S.; Rautiainen, M.; Alexandrov, I. A.; Allen, J.; Asri, M.; Bzikadze, A. V.; Chen, N.-C.; Chin, C.-S.; Diekhans, M.; Flicek, P.; Formenti, G.; Fungtammasan, A.; Garcia Giron, C.; Garrison, E.; Gershman, A.; Gerton, J.; Grady, P. G.; Guarracino, A.; Haggerty, L.; Halabian, R.; Hansen, N. F.; Harris, R.; Hartley, G. A.; Harvey, W. T.; Haukness, M.; Heinz, J.; Hourlier, T.; Hubley, R. M.; Hunt, S. E.; Hwang, S.; Jain, M.; Kesharwani, R. K.; Lewis, A. P.; Li, H.; Logsdon, G. A.; Lucas, J. K.; Makalowski,
10.1101/2022.12.01.518724 — genomics — Posted on 2023-07-11
2960 De novo genome assembly and comparative genomics for a colonial ascidian
Sumner, J. T.; Andrasz, C.; Johnson, C. E.; Wax, S.; Anderson, P. E.; Keeling, E. L.; Davidson, J. M.
10.1101/2023.07.10.548363 — genomics — Posted on 2023-07-11
2962 Urbanization spreads antimicrobial resistant enteric pathogens in wild bird microbiomes
Mourkas, E.; Valdebenito, J. O.; Marsh, H.; Hitchings, M. D.; Cooper, K. K.; Parker, C. T.; Szekely, T.; Johansson, H.; Ellström, P.; Pascoe, B.; Waldenström, J.; Sheppard, S. K.
10.1101/2023.07.11.548564 — genomics — Posted on 2023-07-11
2964 Whole-genome Omics delineates the function of CCM1 within the CmPn networks
Croft, J.; Grajeda, B.; Aguirre, L. A.; Gao, L.; Abou-Fadel, J.; Sheng, V.; Zhang, J.
10.1101/2023.07.11.548554 — molecular biology — Posted on 2023-07-11
2965 Chromatin remodeling of histone H3 variants underlies epigenetic inheritance of DNA methylation
Lee, S. C.; Adams, D. W.; Ipsaro, J. J.; Cahn, J.; Lynn, J.; Kim, H.-S.; Berube, B.; Major, V.; Calarco, J. P.; LeBlanc, C.; Bhattacharjee, S.; Ramu, U.; Grimanelli, D.; Jacob, Y.; Voigt, P.; Joshua-Tor, L.; Martienssen, R. A.
10.1101/2023.07.11.548598 — molecular biology — Posted on 2023-07-11
2967 Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
Yamaguchi, K.; Chen, X.; Rodgers, B.; Miura, F.; Bashtrykov, P.; Ferry, L.; Kirsh, O.; Laisne, M.; Bonhomme, F.; Salinas-Luypaert, C.; Scelfo, A.; Ugur, E.; Arimondo, P. B.; Leonhardt, H.; Kanemaki, M. T.; Fachinetti, D.; Jeltsch, A.; Ito, T.; Defossez, P.-A.
10.1101/2023.07.11.548318 — molecular biology — Posted on 2023-07-11
2968 An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV
Guo, H.; Cho, B.; Hinton, P. R.; He, S.; Yu, Y.; Ramesh, A. K.; Sivaccumar, J. P.; Ku, Z.; Campo, K.; Holland, S.; Sachdeva, S.; Mensch, C.; Dawod, M.; Whitaker, A.; Eisenhauer, P.; Falcone, A.; Honce, R.; Botten, J. W.; Carroll, S. F.; Keyt, B. A.; Womack, A. W.; Strohl, W. R.; Xu, K.; An, Z.; Zhang, N.; Ha, S.; Shiver, J. W.; Fu, T.-M.
10.1101/2023.07.10.548424 — microbiology — Posted on 2023-07-11
2970 LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes
Pradel, B.; Deffieu, M. S.; Robert-Hebmann, V.; Cantaloube, G.; Faure, M.; Chazal, N.; Gaudin, R.; Espert, L.
10.1101/2023.07.11.548555 — microbiology — Posted on 2023-07-11
2971 A side-by-side comparison of peptide-delivered antisense antibiotics employing different nucleotide mimics
Ghosh, C.; Popella, L.; Dhamodharan, V.; Jung, J.; Barquist, L.; Hoebartner, C.; Vogel, J.
10.1101/2023.07.11.548539 — microbiology — Posted on 2023-07-11
2972 Tolerance to Haemophilus influenzae infection in human epithelial cells: insights from a primary cell-based model
Kappler, U.; Henningham, A.; Nasreen, M.; Buultjens, A. H.; Stinear, T. P.; Sly, P.; Fantino, E.
10.1101/2023.07.11.548529 — microbiology — Posted on 2023-07-11
2976 Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor binding domain (RBD)
Kumru, O. S.; Bajoria, S.; Kaur, K.; Hickey, J. M.; Van Slyke, G.; Doering, J.; Berman, K.; Richardson, C.; Lien, H.; Kleanthous, H.; Mantis, N. J.; Joshi, S. B.; Volkin, D. B.
10.1101/2023.07.10.548406 — immunology — Posted on 2023-07-11
2977 Inducing Immune Response with FLASH and Conventional Radiation in Diffuse Midline Glioma (DMG)
Padilla, O.; Minns, H. E.; Wei, H.-J.; Webster-Carrion, A.; Tazhibi, M.; McQuillan, N. M.; Zhang, X.; Gallitto, M.; Yeh, R.; Zhang, Z.; Hei, T. K.; Szalontay, L.; Pavisic, J.; Garty, G.; Garvin, J. H.; Canoll, P. D.; Vanpouille-Box, C.; Menon, V.; Olah, M.; Wu, C.-C.; Rabadan, R.; Gartrell, R. D.
10.1101/2022.11.09.515507 — immunology — Posted on 2023-07-11
2979 A connectome-based model of conscious access in monkey cortex
Klatzmann, U.; Froudist-Walsh, S.; Bliss, D. P.; Theodoni, P.; Mejias, J. F.; Niu, M.; Rapan, L.; Palomero-Gallagher, N.; Sergent, C.; Dehaene, S.; Wang, X.-J.
10.1101/2022.02.20.481230 — neuroscience — Posted on 2023-07-11
2983 Glutamatergic Supramammillary Nucleus Neurons Respond to Threatening Stressors and Promote Active Coping
Escobedo, A.; Holloway, S.-A.; Votoupal, M.; Cone, A. L.; Skelton, H. E.; Legaria, A.; Ndiokho, I.; Floyd, T.; Kravitz, A. V.; Bruchas, M. R.; Norris, A. J.
10.1101/2022.09.22.507167 — neuroscience — Posted on 2023-07-11
2991 Epigenetic variation causes heritable variation in complex traits in the mollusk Biomphalaria glabrata, vector of the human parasite Schistosoma mansoni
Luviano, N.; Lopez, M.; Gawehns, F.; Haegeman, B.; Mouginot, P.; Chaparro, C.; Arimondo, P. B.; Pujol, B.; Pouzol, D.; Cosseau, C.; Grunau, C.
10.1101/2023.07.08.548202 — ecology — Posted on 2023-07-11
2995 Catalyst: Fast and flexible modeling of reaction networks
Loman, T.; Ma, Y.; Ilin, V.; Gowda, S.; Korsbo, N.; Yewale, N.; Rackauckas, C. V.; Isaacson, S. A.
10.1101/2022.07.30.502135 — systems biology — Posted on 2023-07-11
2996 Alternative cell entry mechanisms for SARS-CoV-2 and multiple animal viruses
Ojha, R.; Jiang, A.; Mantyla, E.; Modhiran, N.; Witte, R.; Gaudin, A.; De Zanetti, L.; Gormal, R.; Vihinen-Ranta, M.; Mercer, J.; Suomalainen, M.; Greber, U. F.; Yamauchi, Y.; Yves-Lozach, P.; Helenius, A.; Vapalahti, O.; Young, P.; Watterson, D.; Meunier, F. A.; Joensuu, M.; Balistreri, G.
10.1101/2023.07.02.547368 — microbiology — Posted on 2023-07-11
2998 The tRNA thiolation-mediated translational control is essential for plant immunity
Zheng, X.; Chen, H.; Deng, Z.; Wu, Y.; Zhong, L.; Wu, C.; Chen, Q.; Yan, S.
10.1101/2022.02.13.480182 — plant biology — Posted on 2023-07-11
2999 Emergent digital bio-computation through spatial diffusion and engineered bacteria
Fedorec, A. J. H.; Treloar, N. J.; Wen, K. Y.; Dekker, L.; Ong, Q. H.; Jurkeviciute, G.; Lyu, E.; Rutter, J.; Rosa, L.; Zaikin, A.; Barnes, C. P.
10.1101/2023.07.07.548081 — synthetic biology — Posted on 2023-07-11
3000 Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection
Ghorbani, P.; Kim, S. Y.; Smith, T. K.; Minarrieta, L.; Robert-Gostlin, V.; Kilgour, M. K.; Ilijevska, M.; Alecu, I.; Snider, S. A.; Margison, K. D.; Nunes, J. R.; Woo, D.; Pember, C.; O'Dwyer, C.; Ouellette, J.; Kotchetkov, P.; St-Pierre, J.; Bennett, S. A.; Lacoste, B.; Blais, A.; Nair, M. G.; Fullerton, M. D.
10.1101/2022.09.30.510305 — immunology — Posted on 2023-07-11
3001 Detection and editing of the updated plastid- and mitochondrial-encoded proteomes for Arabidopsis with PeptideAtlas
van Wijk, K. J.; Bentolila, S.; Leppert, T.; Sun, Q.; Sun, Z.; Mendoza, L.; Li, M.; Deutsch, E. W.
10.1101/2023.07.10.548362 — plant biology — Posted on 2023-07-11
3002 In-Silico analysis of Human Insulin Gene for Mirror repeat sequences
Yadav, M.; Sehrawat, B.; Yadav, P.; Kumari, J.; Yadav, P.; Yadav, S.; Yadav, R.; Singh, A.; Yadav, D. S.
10.1101/2023.07.10.548352 — bioinformatics — Posted on 2023-07-11
3007 Diurnal variation of brain activity in the human suprachiasmatic nucleus
Oka, S.; Ogawa, A.; Osada, T.; Tanaka, M.; Nakajima, K.; Kamagata, K.; Aoki, S.; Oshima, Y.; Tanaka, S.; Kirino, E.; Nakamura, T. J.; Konishi, S.
10.1101/2023.07.10.548316 — neuroscience — Posted on 2023-07-11
3009 Extracellular lactate as an alternative energy source for retinal bipolar cells
Calbiague Garcia, V.; Chen, Y.; Cadiz, B.; Paquet-Durand, F.; Schmachtenberg, O.
10.1101/2023.07.10.548331 — physiology — Posted on 2023-07-11
3012 Signatures of Jamming in the Cellular Potts Model
Devanny, A. J.; Lee, D. J.; Kampman, L.; Kaufman, L. J.
10.1101/2023.07.10.548321 — biophysics — Posted on 2023-07-11
3015 Improving genome-scale metabolic models of incomplete genomes with deep learning
Boer, M. D.; Melkonian, C.; Haas, A. F.; Zeiforopoulos, H.; Garza, D.; Dutilh, B. E.
10.1101/2023.07.10.548314 — bioinformatics — Posted on 2023-07-11
3021 Enhanced fungal specificity and in vivo therapeutic efficacy of a C-22 modified FK520 analog against C. neoformans
Rivera, A.; Lim, W.; Park, E.; Dome, P. A.; Hoy, M. J.; Spasojevic, I.; Sun, S.; Floyd Averette, A.; Pina-Oviedo, S.; Juvvadi, P. R.; Steinbach, W. J.; Ciofani, M.; Hong, J.; Heitman, J.
10.1101/2023.06.05.543712 — microbiology — Posted on 2023-07-11
3023 Two sides to every coin: reciprocal introgression line populations in Caenorhabditis elegans
Sterken, M. G.; van Sluijs, L. v.; van Creij, J. W.; Cook, D. E.; Riksen, J. A. G.; Jovic, K.; Schouten, J.; Steeghs, M.; Wang, Y. A.; Stastna, J. J.; Snoek, L. B.; Harvey, S. C.; Kammenga, J. E.
10.1101/2022.08.29.505240 — genetics — Posted on 2023-07-11
3024 Neural mechanisms to incorporate visual counterevidence in self motion estimation
Tanaka, R.; Zhou, B.; Agrochao, M.; Badwan, B. A.; Au, B.; Matos, N. C. B.; Clark, D. A.
10.1101/2023.01.04.522814 — neuroscience — Posted on 2023-07-11
3025 Cortical cell assemblies and their underlying connectivity: an in silico study
Ecker, A.; Egas Santander, D.; Bolanos Puchet, S.; Isbister, J. B.; Reimann, M. W.
10.1101/2023.02.24.529863 — neuroscience — Posted on 2023-07-11
3026 Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
Leibinger, M.; Zeitler, C.; Paulat, M.; Gobrecht, P.; Hilla, A.; Andreadaki, A.; Guthoff, R.; Fischer, D.
10.1101/2023.04.05.535722 — neuroscience — Posted on 2023-07-11
3030 An ancestral vaccine induces anti-Omicron antibodies by hypermutation
Park, S.; Choi, J.; Lee, Y.; Noh, J.; Kim, N.; Lee, J.; Cho, G.; Kim, S.; Yoo, D. K.; Kang, C. K.; Choe, P. G.; Kim, N. J.; Park, W. B.; Kim, S.; Oh, M.-d.; Kwon, S.; Chung, J.
10.1101/2023.03.15.532728 — bioengineering — Posted on 2023-07-11
3033 In Vitro Modulator Responsiveness of 655 CFTR Variants Found in People With CF
Bihler, H.; Sivachenko, A.; Millen, L.; Bhatt, P.; Thakerar Patel, A.; Chin, J.; Bailey, V.; Musisi, I.; LaPan, A.; Allaire, N. E.; Conte, J.; Simon, N. R.; Magaret, A. S.; Raraigh, K. S.; Cutting, G. R.; Skach, W. R.; Bridges, R. J.; Thomas, P. J.; Mense, M.
10.1101/2023.07.07.548159 — pharmacology and toxicology — Posted on 2023-07-11
3034 ESQmodel: biologically informed evaluation of 2-D cell segmentation quality in multiplexed tissue images
Lee, E.; Lee, D.; Fan, W.; Lytle, A.; Fu, Y.; IMAXT Consortium, ; Scott, D. W.; Steidl, C.; Aparicio, S.; Roth, A.
10.1101/2023.07.06.547438 — bioinformatics — Posted on 2023-07-11
3036 Engineered sensor bacteria evolve master-level gameplay through accelerated adaptation
Prakash, S.; Racovita, A.; Varela, C.; Walsh, M.; Galizi, R.; Isalan, M.; Jaramillo, A.
10.1101/2022.04.22.489191 — synthetic biology — Posted on 2023-07-11
3037 XENTURION, a multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients for population-level translational oncology
Leto, S. M.; Grassi, E.; Avolio, M.; Vurchio, V.; Cottino, F.; Ferri, M.; Zanella, E. R.; Di Blasio, L.; Somale, D.; Vara-Messler, M.; Galimi, F.; Sassi, F.; Lupo, B.; Catalano, I.; Pinnelli, M.; Viviani, M.; Sperti, L.; Mellano, A.; Ferrero, A.; Zingaretti, C. C.; Puliafito, A.; Primo, L.; Bertotti, A.; Trusolino, L.
10.1101/2023.07.10.548375 — cancer biology — Posted on 2023-07-11
3038 Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer
Murali Shankar, N.; Ortiz Montero, P.; Kurzyukova, A.; Rackwitz, W.; Künzel, S.; Wels, W. S.; Tonn, T.; Knopf, F.; Eitler, J.
10.1101/2023.07.11.548344 — cancer biology — Posted on 2023-07-11
3039 Statistical integration of multi-omics and drug screening data from cell lines
El Bouhaddani, S.; Höllerhage, M.; Uh, H.-W.; Bickle, M.; Moebius, C.; Höglinger, G.; Houwing-Duistermaat, J.
10.1101/2022.08.10.503452 — bioinformatics — Posted on 2023-07-11
3042 RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration
Matsuo, K.; Asamitsu, S.; Maeda, K.; Kawakubo, K.; Komiya, G.; Kudo, K.; Sakai, Y.; Hori, K.; Ikenoshita, S.; Usuki, S.; Funahashi, S.; Kawata, Y.; Mizobata, T.; Shioda, N.; Yabuki, Y.
10.1101/2023.07.10.548322 — molecular biology — Posted on 2023-07-11
3043 Sox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness.
Faleeva, M.; Ahmad, S.; Lynham, S.; Watson, G.; Whitehead, M. C.; Cox, S.; Shanahan, C.
10.1101/2023.05.03.539285 — molecular biology — Posted on 2023-07-11
3044 Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes
Son, K.; Takhaveev, V.; Mor, V.; Yu, H.; Dillier, E.; Zilio, N.; Pullen, N. J. L.; Ivanov, D.; Ulrich, H. D.; Sturla, S. J.; Scharer, O. D.
10.1101/2023.07.10.548294 — molecular biology — Posted on 2023-07-11
3045 Modeling Antigen-Specific T Cell Dynamics Following Hepatitis B Vaccination indicates differences between conventional and regulatory T cell dynamics
Besbassi, H.; Elias, G.; Meysman, P.; Jansens, H.; Laukens, K.; Van Damme, P.; Thomas, P.; Hens, N.; Beutels, P.; Ogunjimi, B.
10.1101/2023.05.27.542434 — immunology — Posted on 2023-07-11
3046 Decision-making processes in perceptual learning depend on effectors
Ivanov, V.; Manenti, G.; Sudmann, S. S.; Kagan, I.; Schwiedrzik, C. M.
10.1101/2022.06.29.498152 — neuroscience — Posted on 2023-07-11
3053 A large sensory and multi-omics evaluation unraveled chemical and genetic basis of orange flavor
Fan, Z.; Jeffries, K. A.; Sun, X.; Olmedo, G.; Zhao, W.; Mattia, M. R.; Stover, E.; Manthey, J. A.; Baldwin, E. A.; Lee, S.; Gmitter, F. G.; Plotto, A.; Bai, J.
10.1101/2023.07.10.548426 — genetics — Posted on 2023-07-11
3054 CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Wang, B.; Liang, Z.; Tan, T.; Zhang, M.; Jiang, Y.; Shang, Y.; Gao, X.; Song, S.; Wang, R.; Chen, H.; Liu, J.; Li, J.; Ren, Y.; Liu, P.
10.1101/2023.02.15.528649 — cell biology — Posted on 2023-07-11
3055 Pathogenic aggregates alter actin organization and cellular viscosity resulting in stalled clathrin mediated endocytosis
Singh, S. B.; Rajput, S. S.; Sharma, A.; Ananthanarayanan, V.; Nandi, A.; Patil, S. P. V.; majumdar, a.; Subramanyam, D.
10.1101/2023.07.10.548473 — cell biology — Posted on 2023-07-11
3056 Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix
Warner, H.; Franciosa, G.; van der Borg, G.; Faas, F.; Koenig, C.; de Boer, R.; Classens, R.; Maassen, S.; Baranov, M.; Mahajan, S.; Dabral, D. D.; Coenen, B.; Bianchi, F.; van Hilten, N.; Risselada, H. J.; Roos, W. H.; Olsen, J.; Querol Cano, L.; van den Bogaart, G. V.
10.1101/2023.07.10.548429 — cell biology — Posted on 2023-07-11
3057 Targeting human γδ T cells as a potent and safe alternative to pan-T cells bispecific cell engagers
Boutin, L.; Barjon, C.; Lafrance, L.; Senechal, E.; Bourges, D.; Vigne, E.; Scotet, E.
10.1101/2023.07.10.548307 — immunology — Posted on 2023-07-11
3059 Altered spread of waves of activities at large scale is influenced by cortical thickness organization in temporal lobe epilepsy: a MRI-hdEEG study
Duma, G. M.; Pellegrino, G.; Rabuffo, G.; Danieli, A.; Antoniazzi, L.; Vitale, V.; Scotto Opipari, R.; Bonanni, P.; Sorrentino, P.
10.1101/2023.07.05.547809 — neuroscience — Posted on 2023-07-11
3061 Integrative analyses uncover mechanisms by which aging drives B cell lymphoma
Castro, J. P.; Shindyapina, A. V.; Barbieri, A.; Ying, K.; Strelkova, O. S.; Paulo, J. A.; Tyshkovskiy, A.; Meinl, R.; Kerepesi, C.; Petrashen, A. P.; Mariotti, M.; Meer, M.; Hu, Y.; Karamyshev, A.; Losyev, G.; Indzhykulian, A. A.; Gygi, S. P.; Sedivy, J. M.; Manis, J. P.; Gladyshev, V. N.
10.1101/2021.02.23.432500 — cancer biology — Posted on 2023-07-11
3062 OPTIMIZING THERAPEUTIC TARGETS FOR BREAST CANCER USING BOOLEAN NETWORK MODELS
Sgariglia, D.; Goncalves Carneiro, F. R.; Vidal de Carvalho, L. A.; Pedreira, C. E.; Carels, N.; Barbosa da Silva, F. A.
10.1101/2023.05.10.540187 — cancer biology — Posted on 2023-07-11
3063 Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
Chavdoula, E.; Anastas, V.; La Ferlita, A.; Aldana, J.; Carota, G.; Spampinato, M.; Soysal, B.; Cosentini, I.; Parashar, S.; Sircar, A.; Nigita, G.; Sehgal, L.; Freitas, M. A.; Tsichlis, P. N.
10.1101/2023.07.07.548031 — cancer biology — Posted on 2023-07-11
3067 Poly-omic risk scores predict inflammatory bowel disease diagnosis
Arehart, C. H.; Sterrett, J. D.; Garris, R. L.; Quispe-Pilco, R. E.; Gignoux, C. R.; Evans, L. M.; Stanislawski, M. A.
10.1101/2022.09.14.508056 — bioinformatics — Posted on 2023-07-11
3069 Genotype imputation accuracy and the quality metrics of the minor ancestry in multi-ancestry reference panels
Shi, M.; Tanikawa, C.; Munter, H. M.; Akiyama, M.; Koyama, S.; Tomizuka, K.; Matsuda, K.; Lathrop, G. M.; Terao, C.; Koido, M.; Kamatani, Y.
10.1101/2023.05.30.542466 — bioinformatics — Posted on 2023-07-11
3070 Alternative splicing is coupled to gene expression in a subset of variably expressed genes
Karlebach, G.; Steinhaus, R.; Danis, D.; Devoucoux, M.; Anczukow, O.; Sheynkman, G.; Seelow, D.; Robinson, P. N.
10.1101/2023.06.13.544742 — genomics — Posted on 2023-07-11
3071 Bursts of novel composite gene families at major nodes in animal evolution
Mulhair, P. O.; Moran, R. J.; Pathmanathan, J. s.; Sussfeld, D.; Creevey, C. J.; Siu-Ting, K.; Whelan, F. J.; Pisani, D.; Constantinides, B.; Pelletier, E.; lopez, p.; Bapteste, E.; McInerney, J. O.; O'Connell, M. J.
10.1101/2023.07.10.548381 — evolutionary biology — Posted on 2023-07-11
3074 Genetic compatibility exceeds possible good genes effects of sexual selection in lake char
Garaud, L.; Nusbaumer, D.; de Guttry, C.; Marques da Cunha, L.; Ancay, L.; Atherton, A.; Lasne, E.; Wedekind, C.
10.1101/2022.03.03.482834 — evolutionary biology — Posted on 2023-07-11
3077 Divergent ecological responses to typhoon disturbance revealed via landscape-scale acoustic monitoring
Ross, S. R. P.-J.; Friedman, N. R.; Dudley, K. L.; Yoshida, T.; Yoshimura, M.; Economo, E. P.; Armitage, D. W.; Donohue, I.
10.1101/2023.01.11.523682 — ecology — Posted on 2023-07-11
3079 Impact of environmental factors on calling behavior in midshipman fish across ocean basins
Kok, A.; Kim, E. B.; Rowell, T. J.; Margolina, T.; Joseph, J. E.; Peavey Reeves, L. E.; Hatch, L. T.; Baumann-Pickering, S.
10.1101/2023.07.11.547287 — ecology — Posted on 2023-07-11
3081 Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology
Tangeman, J. A.; Rebull, S. M.; Grajales-Esquivel, E.; Weaver, J. M.; Bendezu-Sayas, S.; Robinson, M. L.; Lachke, S. A.; Del Rio-Tsonis, K.
10.1101/2023.07.10.548451 — developmental biology — Posted on 2023-07-11
3082 Replisome loading reduces chromatin motion independent of DNA synthesis
Pabba, M. K.; Ritter, C.; Chagin, V. O.; Meyer, J.; Celikay, K.; Stear, J. H.; Loerke, D.; Kolobynina, K.; Prorok, P.; Schmid, A. K.; Leonhardt, H.; Rohr, K.; Cardoso, M. C.
10.1101/2023.03.07.531331 — cell biology — Posted on 2023-07-11
3086 Stress-Induced Mucin 13 Reductions Drive Intestinal Microbiome Shifts and Despair Behaviors
Rivet-Noor, C.; Merchak, A. R.; Render, C.; Gay, N.; Beiter, R. M.; Brown, R.; Keeler, A.; Moreau, G. B.; Li, S.; Olgun, D.; Steigmeyer, A. D.; Ofer, R.; Phan, T. M. H.; Vemuri, K.; Chen, L.; Mahoney, K.; Shin, J.-B.; Malaker, S. A.; Deppmann, C. D.; Verzi, M.; Gaultier, A.
10.1101/2022.10.13.512135 — microbiology — Posted on 2023-07-11
3088 Effects of sexual dimorphism and estrous cycle on C. difficile infections in rodent models
Phan, J. R.; Washington, M.; Do, D. M.; Mata, T. V.; Niamba, M.; Heredia, E.; Soriano, R.; Hassan, C.; Cross, C. L.; Abel-Santos, E.
10.1101/2023.07.05.547871 — microbiology — Posted on 2023-07-11
3090 De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
Koh, J.; Woo, Y. D.; Yoo, H. J.; Choi, J.-P.; Kim, S. H.; Chang, Y.-S.; Jung, K. C.; Kim, J. H.; Jeon, Y. K.; Kim, H. Y.; Chung, D. H.
10.1101/2023.02.15.528598 — immunology — Posted on 2023-07-11
3092 Enhancing associative learning in rats with a computationally designed training protocol
Zhang, X. O.; Zhang, Y.; Cho, C. E.; Engelke, D. S.; Smolen, P.; Byrne, J. H.; Do Monte, F. H.
10.1101/2022.06.08.495364 — neuroscience — Posted on 2023-07-11
3098 An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing
Li, Z.; Zhang, B.; Chan, J. J.; Tabatabaeian, H.; Tong, Q. Y.; Chew, X. H.; Fan, X.; Driguez, P.; Chan, C.; Cheong, F.; Wang, S.; Siew, B. E.; Tan, I. J.-W.; Lee, K. Y.; Lieske, B.; Cheong, W.-K.; Kappei, D.; Tan, K.-K.; Gao, X.; Tay, Y.
10.1101/2023.04.21.536771 — cancer biology — Posted on 2023-07-11
3099 The orphan nuclear receptor Nr2f6 impairs skeletal muscle oxidative capacity and regulates muscle mass in mice.
Guimaraes, D. S. P. S. F.; Barrios, N. M. F.; de Oliveira, A. G.; Rizo-Roca, D.; Jollet, M.; Smith, J. A. B.; Araujo, T. R.; da Cruz, M. V.; Vieira, A. S.; Hirabara, S. M.; Marconato, E.; Krook, A.; Zierath, J. R.; Silveira, L. d. R.
10.1101/2023.05.17.540900 — biochemistry — Posted on 2023-07-11
3100 Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs
Johnson, K. R.; Kilikevicius, A.; Hofman, C.; Hu, J.; Liu, Y.; Aguilar, S.; Graswich, C.; Han, Y.; Wang, T.; Wescott, J.; Brekken, R. A.; Peng, L.; Karagkounis, G.; Corey, D. R.
10.1101/2023.07.07.548119 — biochemistry — Posted on 2023-07-11
3101 Use of nanomaterials-modified carbon microfiber electrode material for superior electrochemical performance in lake sediment inoculated microbial fuel cells
Somasiri, M.; Amandani, T.; Basnayake, C.; Ahsan, A.; Herath, A. C.; Dilangani, G. P.; Bandara, S.; Nazeer, Z.; Thilini, N.; Kyazze, G.; Fernando, E. Y.
10.1101/2023.07.10.548441 — bioengineering — Posted on 2023-07-10
3103 High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma
Greatbatch, C. J.; Lu, Q.; Hung, S.; Wing, K.; Liang, H.; Han, X.; Zhou, T.; Siggs, O.; Mackey, D.; Cook, A.; Senabouth, A.; Liu, G.-S.; Craig, J.; MacGregor, S.; Powell, J.; Hewitt, A.
10.1101/2023.07.10.548340 — genetics — Posted on 2023-07-10
3104 C-terminal truncation of CXCL10 attenuates inflammatory activity but retains angiostatic properties
Dillemans, L.; Yu, K.; De Zutter, A.; Noppen, S.; Gouwy, M.; Berghmans, N.; De Bondt, M.; Vanbrabant, L.; Brusselmans, S.; Martens, E.; Schols, D.; Marques, P. E.; Struyf, S.; Proost, P.
10.1101/2023.07.10.548382 — immunology — Posted on 2023-07-10
3106 Virally induced CRISPR/Cas9-based knock-in of fluorescent albumin allows long-term visualization of cerebral circulation in infant and adult mice
Vittani, M.; Knak, P. A. G.; Fukuda, M.; Nagao, M.; Wang, X.; Kjaerby, C.; Konno, A.; Hirai, H.; Nedergaard, M.; Hirase, H.
10.1101/2023.07.10.548084 — neuroscience — Posted on 2023-07-10
3109 Transposable element insertions are associated with Batesian mimicry in the pantropical butterfly Hypolimnas misippus
Orteu, A.; Kucka, M.; Katili, E.; Ngumbao, C.; Gordon, I. J.; Ng'iru, I.; Talavera, G.; Warren, I. A.; Collins, S.; ffrench-Constant, R. H.; Martins, D. J.; Chan, Y. F.; Jiggins, C. D.; Martin, S. H.
10.1101/2023.07.10.548380 — evolutionary biology — Posted on 2023-07-10
3110 Genome-Wide Association Study for Yield and Yield related traits reveals MarkerTrait Associations in Germplasm lines of Rice
Shivani, D.; Rahaman, A. F.; Jabeen, F.; Kumar, J. A.; Reddy, K. C.; Dhananjaya, D. K. G.; Subbarao, L. V.; Kallakuri, S.; Venkatanagappa, S.; Sundaram, R. M.
10.1101/2023.07.10.548364 — molecular biology — Posted on 2023-07-10
3111 Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes
Son, K.; Takhaveev, V.; Mor, V.; Yu, H.; Dillier, E.; Zilio, N.; Pullen, N. J. L.; Ivanov, D.; Ulrich, H. D.; Sturla, S. J.; Scharer, O. D.
10.1101/2023.07.10.548294 — molecular biology — Posted on 2023-07-10
3115 IFNγ modestly contributes to disease progression in the Ndufs4(-/-) model of Leigh syndrome while IP10 is dispensable
Hanaford, A. R.; Khanna, A.; James, K.; Truong, V.; Liao, R. W.; Chen, Y.; Mulholland, M.; Kayser, E.-B.; Hsieh, E. S.; Sedensky, M.; Morgan, P.; Kalia, V.; Sarkar, S.; Johnson, S. C.
10.1101/2023.07.09.548281 — pathology — Posted on 2023-07-10
3116 Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization
Sanchez, J. C.; Montemayor, E. J.; Ploscariu, N. T.; Parrell, D.; Baumgardt, J. K.; Yang, J. E.; Sibert, B.; Cai, K.; Wright, E. R.
10.1101/2023.07.10.548443 — biophysics — Posted on 2023-07-10
3119 The pathogenic T42A mutation in SHP2 rewires interaction specificity and enhances signaling
van Vlimmeren, A. E.; Voleti, R.; Chartier, C. A.; Jiang, Z.; Karandur, D.; Shah, N. H.
10.1101/2023.07.10.548257 — biochemistry — Posted on 2023-07-10
3120 Harnessing the power of whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation
Cabanes-Creus, M.; Liao, S. H. Y.; Navarro, R. G.; Knight, M.; Nazareth, D.; Lau, N.-S.; Ly, M.; Zhu, E.; Roca-Pinilla, R.; Bugallo Delgado, R.; Baltazar, G.; Westhaus, A.; Merjane, J.; Crawford, M.; McCaughan, G. W.; Unzu, C.; Gonzalez-Aseguinolaza, G.; Alexander, I. E.; Pulitano, C.; Lisowski, L.
10.1101/2023.07.10.548299 — molecular biology — Posted on 2023-07-10
3122 RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration
Matsuo, K.; Asamitsu, S.; Maeda, K.; Kawakubo, K.; Komiya, G.; Kudo, K.; Sakai, Y.; Hori, K.; Ikenoshita, S.; Usuki, S.; Funahashi, S.; Kawata, Y.; Mizobata, T.; Shioda, N.; Yabuki, Y.
10.1101/2023.07.10.548322 — molecular biology — Posted on 2023-07-10
3123 No-go decay dampens zinc finger protein mRNAs in vertebrates
Ishibashi, K.; Shichino, Y.; Han, P.; Inada, T.; Kimura, S.; Iwasaki, S.; Mishima, Y.
10.1101/2023.07.10.548350 — molecular biology — Posted on 2023-07-10
3129 OrtR regulates the oxidative stress response of Streptococcus mutans
Li, Y.; Yu, S.; Huang, J.; Liu, Y.; Li, J.; Zhang, Q.; Wang, Y.; Gong, T.; Ma, Q.; Zou, J.
10.1101/2023.07.10.548324 — microbiology — Posted on 2023-07-10
3130 Identification of Spinster Homolog 3 as a novel putative LL-37 receptor
Correa, A. B.; de Lima, T. M.; Ariga, S. K.; Pinheiro Da Silva, F.
10.1101/2023.07.07.548096 — immunology — Posted on 2023-07-10
3134 Quantifying visual acuity in Heliconius butterflies
Wright, D. S.; Manel, A. N.; Guachamin-Rosero, M.; Chamba-Vaca, P.; Bacquet, C. N.; Merrill, R. M.
10.1101/2023.07.10.548283 — evolutionary biology — Posted on 2023-07-10
3136 Nischarin negatively impacts ShcD-mediated tumor cell migration
Hago, R. A.; Wong, S. P.; Hachim, M. Y.; Hachim, I. Y.; Saber-Ayad, M.; Prigent, S. A.; Ahmed, S. B.
10.1101/2023.07.10.547766 — molecular biology — Posted on 2023-07-10
3137 Methylotrophy in the Mire: direct and indirect routes for methane production in thawing permafrost
Ellenbogen, J. B.; Borton, M. A.; McGivern, B. B.; Cronin, D. R.; Hoyt, D. W.; Freire-Zapata, V.; McCalley, C. K.; Varner, R. K.; Crill, P. M.; Wehr, R. A.; Chanton, J. P.; Woodcroft, B. J.; Tfaily, M. M.; Tyson, G. W.; Rich, V. I.; Wrighton, K. C.
10.1101/2023.07.09.548291 — microbiology — Posted on 2023-07-10
3138 Proteome profiling of nasopharynx reveals pathophysiological signature of COVID-19 disease severity
Ooi, A.; Esau, L. E.; Pugachev, A.; Groen, A.; Sara Mfarrej, R.; Salunke, R. P.; Subudhi, A. K.; Ben-Rached, F.; Alofi, F.; Alsomali, A.; Khogeer, A.; Hashem, A. M.; Almontashiri, N.; Magistretti, P. J.; Hala, S.; Pain, A.
10.1101/2023.07.09.548285 — immunology — Posted on 2023-07-10
3140 Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota
Kreisinger, J.; Dooley, J.; Singh, K.; Cizkova, D.; Schmiedova, L.; Bendova, B.; Liston, A.; Moudra, A.
10.1101/2023.07.10.547212 — immunology — Posted on 2023-07-10
3141 Phase-Amplitude Coupling Detection and Analysis of Human 2-Dimensional Neural Cultures in Multi-well Microelectrode Array in Vitro
Salimpour, Y.; Anderson, W. S.; Dastgheyb, R.; Liu, S.; Ming, G.-L.; Song, H.; Maragakis, N. J.; Habela, C. W.
10.1101/2023.07.08.548227 — neuroscience — Posted on 2023-07-10
3143 Self-propagating wave drives noncanonical antidurotaxis of skull bones in vivo
Dang, Y.; Lattner, J.; Lahola-Chomiak, A.; Alves-Afonso, D.; Ulbricht, E.; Taubenberger, A. V.; Rulands, S.; Tabler, J.
10.1101/2023.07.10.547677 — biophysics — Posted on 2023-07-10
3145 Structure of the human Duffy antigen receptor
Saha, S.; Khanppnavar, B.; Maharana, J.; Kim, H.; Carino, C. M. C.; Daly, C.; Houston, S.; Kumari, P.; Yadav, P. N.; Plouffe, B.; Inoue, A.; Chung, K. Y.; Banerjee, R.; Korkhov, V. M.; Shukla, A. K.
10.1101/2023.07.09.548245 — biochemistry — Posted on 2023-07-10
3147 miR-324 mediates bone homeostasis through the regulation of osteoblast and osteoclast differentiation and activity
Hayman, D. J.; Lin, H.; Prior, A.; Charlesworth, G.; Johnson de Sousa Brito, F. M.; Hao, Y.; Patel, K.; Soul, J.; Clark, I. M.; Pirog, K. A.; Barter, M. J.; van 't Hof, R. J.; Young, D. A.
10.1101/2023.07.10.548366 — cell biology — Posted on 2023-07-10
3151 Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis
Herruzo, E.; Sanchez-Diaz, E.; Gonzalez-Arranz, S.; Santos, B.; Carballo, J. A.; San-Segundo, P. A.
10.1101/2023.07.10.548332 — cell biology — Posted on 2023-07-10
3153 Machine Learning identifies conserved traits that influence lifespan and healthspan responses to dietary restriction
Hilsabeck, T. A.; Wilson, K. A.; Narayan, V. P.; Carrera, E.; Brem, R. B.; Campisi, J. A.; Kapahi, P.
10.1101/2023.07.09.548232 — systems biology — Posted on 2023-07-10
3154 Multifactorial analysis of terminator performance on heterologous gene expression in Physcomitrella
Niederau, P. A.; Egle, P.; Willig, S.; Parsons, J.; Hoernstein, S. N. W.; Decker, E. L.; Reski, R.
10.1101/2023.06.30.547182 — plant biology — Posted on 2023-07-10
3157 Nanopore sequencing for real-time genomic surveillance of Plasmodium falciparum
Girgis, S. T.; Adika, E.; Nenyewodey, F. E.; Senoo Jnr, D. K.; Ngoi, J. M.; Bandoh, K.; Lorenz, O.; van de Steeg, G.; Harrott, A. J. R.; Nsoh, S.; Judge, K.; Pearson, R. D.; Almagro-Garcia, J.; Saiid, S.; Atampah, S.; Amoako, E. K.; Morang'a, C. M.; Asoala, V.; Adjei, E. S.; Burden, W.; Roberts-Sengier, W.; Drury, E.; Pierce, M. L.; Goncalves, S.; Awandare, G. A.; Kwiatkowski, D. P.; Amenga-Etego, L. N.; Hamilton, W. L.
10.1101/2022.12.20.521122 — genomics — Posted on 2023-07-10
3162 Tetracycline transactivator overexpression in keratinocytes triggers a TRPV1 primary sensory neuron-dependent neuropathic itch
Crowther, A.; Kashem, S.; Jewell, M. E.; Chang, H. L.; Casillas, M. R.; Midavaine, E.; Rodriguez, S.; Braz, J.; Kania, A.; Basbaum, A.
10.1101/2023.07.09.548214 — neuroscience — Posted on 2023-07-10
3164 Sex-Specific Effects of Anxiety on Cognition and Activity-Dependent Neural Networks: Insights from (Female) Mice and (Wo)Men
Hunsberger, H.; Lee, S.; Jin, M.; Lanio, M.; Whye, A.; Cha, J.; Scarlata, M.; Jayaseelan, K.; Denny, C. A.
10.1101/2023.07.07.548180 — neuroscience — Posted on 2023-07-10
3168 A novel naive Bayes approach to identifying grooming behaviors in the force-plate actometric platform
Anderson, C. J.; Cadeddu, R.; Anderson, D. N.; Huxford, J. A.; VanLuik, E. R.; Odeh, K.; Pittenger, C.; Pulst, S. M.; Bortolato, M.
10.1101/2023.07.08.548198 — neuroscience — Posted on 2023-07-10
3169 Increasing adult neurogenesis protects mice from epilepsy.
Jain, S.; LaFrancois, J. J.; Gerencer, K.; Botterill, J. J.; Kennedy, M.; Criscuolo, C.; Scharfman, H.
10.1101/2023.07.08.548217 — neuroscience — Posted on 2023-07-10
3170 Whole-brain deactivations precede uninduced mind-blanking reports
Boulakis, P. A.; Mortaheb, S.; van Calster, L.; Majerus, S.; Demertzi, A.
10.1101/2023.04.14.536362 — neuroscience — Posted on 2023-07-10
3171 Multi-organ Metabolic Model of Zea mays Connects Temperature Stress with Thermodynamics-Reducing Power-Energy Generation Axis
Chowdhury, N. B.; Decouard, B.; Quillere, I.; Rigault, M.; Sajeevan, K. A.; Acharya, B.; Chowdhury, R.; Hirel, B.; Dellagi, A.; Maranas, C. D.; Saha, R.
10.1101/2023.07.09.548275 — plant biology — Posted on 2023-07-10
3172 Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake
Ferrari, A.; Whang, E.; Xiao, X.; Kennelly, J. P.; Romartinez- Alonso, B.; Mack, J. J.; Weston, T.; Chen, K.; Kim, Y.; Tol, M.; Bideyan, L.; Nguyen, A.; Gao, Y.; Cui, L.; Bedard, A. H.; Sandhu, J.; Lee, S. D.; Fairall, L.; Williams, K. J.; Song, W.; Munguia, P.; Russell, R. A.; Martin, M. G.; Jung, M. E.; Jiang, H.; Schwabe, J. W.; Young, S. G.; Tontonoz, P.
10.1101/2023.07.07.548168 — physiology — Posted on 2023-07-10
3173 Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants
Tang, Z.; Zhao, J.; Li, Y.; Tomer, S.; Selvaraju, M.; Tien, N.; Sun, D.; Johnson, D. K.; Zhen, A.; Li, P.; Wang, J.
10.1101/2023.07.02.547363 — pharmacology and toxicology — Posted on 2023-07-10
3174 Fully Automated Sequential Immunofluorescence (seqIF) for Hyperplex Spatial Proteomics
Rivest, F.; Eroglu, D.; Pelz, B.; Kowal, J.; Kehren, A.; Procopio, M. G.; Bordignon, P.; Peres, E.; Ammann, M.; Dorel, E.; Scalmazzi, S.; Bruno, L.; Ruegg, M.; Campargue, G.; Casqueiro, G.; Arn, L.; Fischer, J.; Brajkovic, S.; Joris, P.; Cassano, M.; Dupouy, D.
10.1101/2023.07.07.548135 — cancer biology — Posted on 2023-07-10
3175 MethNet: a robust approach to identify regulatory hubs and their distal targets in cancer
Sakellaropoulos, T.; Do, C.; Jiang, G.; Cova, G.; Meyn, P.; Dimartino, D.; Ramaswami, S.; Heguy, A.; Tsirigos, A.; Skok, J. A.
10.1101/2023.07.07.548142 — cancer biology — Posted on 2023-07-10
3178 Prediction of Alzheimer's Disease from Single Cell Transcriptomics Using Deep Learning
Srivastava, A.; Dhall, A.; Patiyal, S.; Arora, A.; Jarwal, A.; Raghava, G. P. S.
10.1101/2023.07.07.548171 — bioinformatics — Posted on 2023-07-10
3180 Pasa: Leverage population pangenome graph to scaffold prokaryote genome assemblies.
Do, V. H.; Nguyen, S. H.; Le, D. Q.; Nguyen, T. T.; Nguyen, C. H.; Ho, T. H.; Nam, V. S.; Nguyen, T.; Nguyen, H. A.; Cao, M. D.
10.1101/2023.07.09.548288 — bioinformatics — Posted on 2023-07-10
3182 Improving the Circularization Efficiency, Stability and Translatability of Circular RNA by circDesign
Xu, C.; Zhang, L.; Wang, W.; Tang, Y.; Wang, Q.; An, J.; Xu, H.; Ge, Y.; Zhu, H.; Wang, H.; Li, B.; Wang, X.; Qiu, X.; Shen, M.; Chen, G.; Shen, H.; Huang, L.; Li, H.
10.1101/2023.07.09.548293 — bioengineering — Posted on 2023-07-10
3183 Microengineering 3D Collagen Matrices with Tumor-Mimetic Gradients in Fiber Alignment
Joshi, I. M.; Mansouri, M.; Ahmed, A.; Simon, R.; Esmaili, P. B.; Desa, D. E.; Elias, T.; Brown, E.; Abhyankar, V. V.
10.1101/2023.07.09.548253 — bioengineering — Posted on 2023-07-10
3185 DISCOVERY AND VALIDATION OF GENES DRIVING DRUG-INTAKE AND RELATED BEHAVIORAL TRAITS IN MICE
Roy, T.; Bubier, J. A.; Dickson, P. E.; Wilcox, T.; Ndukum, J.; Clark, J. W.; Rizzo, S. J. S.; Crabbe, J. C.; Denegre, J.; Svenson, K. L.; Braun, R. E.; Kumar, V.; Murray, S. A.; White, J. K.; Philip, V.; Chesler, E.
10.1101/2023.07.09.548280 — genetics — Posted on 2023-07-10
3187 Hebbian learning of stimulus-response associations using transcranial magnetic stimulation
Held, L. K.; Cracco, E.; Bardi, L.; Kiraga, M.; Cristianelli, E.; Brass, M.; Abrahamse, E.; Braem, S.
10.1101/2023.07.07.547977 — neuroscience — Posted on 2023-07-10
3188 7-Tesla evidence for columnar and rostral-caudal organization of the human periaqueductal grey response in the absence of threat: a working memory study.
Fischbach, A. K.; Satpute, A. B.; Quigley, K. S.; Kragel, P. A.; Chen, D.; Bianciardi, M.; Wald, L. L.; Wager, T. D.; Choi, J.-K.; Zhang, J.; Feldman Barrett, L.; Theriault, J. E.
10.1101/2022.12.21.521479 — neuroscience — Posted on 2023-07-10
3189 Genetic Variations and Altered Blood mRNA Level of Circadian Genes and BDNF as Risk Factors of Post-Stroke Cognitive Impairment among Eastern Indians
Sadhukhan, D.; Biswas, A.; Mishra, S.; Maji, D.; Mitra, P.; Mukherjee, P.; Podder, G.; Ray, B. K.; Biswas, A.; Banerjee, T. K.; Hui, S. P.; Deb, I.
10.1101/2023.07.07.548090 — neuroscience — Posted on 2023-07-10
3192 Learning and memory deficits produced by aspartame are heritable via the paternal lineage
Jones, S. K.; McCarthy, D. M.; Stanwood, G. D.; Schatschneider, C.; Bhide, P. G.
10.1101/2023.07.09.548248 — neuroscience — Posted on 2023-07-10
3193 Periodontitis promotes bacterial extracellular vesicle-induced neuroinflammation in the brain and trigeminal ganglion
Ha, J. Y.; Seok, J.; Kim, S.-J.; Jung, H.-J.; Ryu, K.-Y.; Nakamura, M.; Jang, I.-S.; Hong, S.-H.; Lee, Y.; Lee, H.-J.
10.1101/2023.07.09.548287 — pathology — Posted on 2023-07-10
3195 The inhibitory mechanism of a small protein reveals its role in antimicrobial peptide sensing
Jiang, S.; Steup, L. C.; Kippnich, C.; Lazaridi, S.; Malengo, G.; Lemmin, T.; Yuan, J.
10.1101/2022.12.22.521624 — microbiology — Posted on 2023-07-10
3196 RNA-to-image multi-cancer synthesis using cascaded diffusion models
Carrillo-Perez, F.; Pizurica, M.; Zheng, Y.; Nandi, T. N.; Madduri, R.; Shen, J.; Gevaert, O.
10.1101/2023.01.13.523899 — bioinformatics — Posted on 2023-07-10
3202 Attentional effects on local V1 microcircuits explain selective V1-V4 communication
Katsanevaki, C.; Bastos, A. M.; Cagnan, H.; Bosman, C. A.; Friston, K. J.; Fries, P.
10.1101/2022.03.14.484223 — neuroscience — Posted on 2023-07-10
3203 ASD mutation of Katnal2 impairs ependymal ciliary motion and causes hydrocephalus
Qiu, S.; Cao, H.; Xue, Y.; Zhao, W.; Xie, S.; Wu, N.; Song, M.; Pan, Y.-H.; Baas, P. W.; Ma, J.; Yuan, X.-B.
10.1101/2023.07.03.547302 — neuroscience — Posted on 2023-07-10
3205 DataPLAN: a web-based data management plan generator for the plant sciences
Zhou, X.-R.; Beier, S.; Brilhaus, D.; Rodrigues, C. M.; Mühlhaus, T.; von Suchodoletz, D.; Twyman, R. M.; Usadel, B.; Kranz, A.
10.1101/2023.07.07.548147 — plant biology — Posted on 2023-07-10
3206 SOL3D: Soft-lithography on 3D vat polymerised moulds for fast, versatile, and accessible high-resolution fabrication of customised multiscale cell culture devices with complex designs
Hagemann, C.; Bailey, M. C. D.; Carraro, E.; Khokhar, N.; Lionello, V. M.; Suklai, P.; Moreno-Gonzalez, C.; O'Toole, K.; Konstantinou, G.; Joshi, S.; Giagnorio, E.; Bergholt, M.; Imbert, A.; Tedesco, F. S.; Serio, A.
10.1101/2022.02.22.481424 — bioengineering — Posted on 2023-07-10
3207 Real-Time Spatiotemporal Measurement of Extracellular Signaling Molecules Using an Aptamer Switch-Conjugated Hydrogel Matrix
Park, C. H.; Thompson, I. A. P.; Newman, S. S.; Hein, L. A.; Lian, X.; Fu, K.; Pan, J.; Eisenstein, M.; Soh, H. T.
10.1101/2023.07.09.548040 — bioengineering — Posted on 2023-07-10
3208 Detecting differential transcript usage in complex diseases with SPIT
Erdogdu, B.; Varabyou, A.; Hicks, S. C.; Salzberg, S. L.; Pertea, M.
10.1101/2023.07.10.548289 — genomics — Posted on 2023-07-10
3211 Complex Sphingolipid Profiling and Identification of an Inositol Phosphorylceramide Synthase in Dictyostelium discoideum
Listian, S. A.; Kol, M.; Ufelmann, E.; Eising, S.; Froehlich, F.; Walter, S.; Holthuis, J. C. M.; Barisch, C.
10.1101/2023.07.07.548115 — cell biology — Posted on 2023-07-10
3212 Label-free ghost cytometry for manufacturing of cell therapy products
Teranishi, K.; Wagatsuma, K.; Toda, K.; Nomaru, H.; Yanagihashi, Y.; Ochiai, H.; Akai, S.; Mochizuki, E.; Onda, Y.; Nakagawa, K.; Sugimoto, K.; Takahashi, S.; Yamaguchi, H.; Ota, S.
10.1101/2023.07.09.545884 — cell biology — Posted on 2023-07-10
3213 An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes
McCafferty, C. L.; Papoulas, O.; Lee, C.; Bui, K. H. L.; Taylor, D. W.; Marcotte, E. M.; Wallingford, J. B.
10.1101/2023.07.09.548259 — cell biology — Posted on 2023-07-10
3214 Molecular and structural basis of the heterochromatin-specific chromatin remodeling activity by Arabidopsis DDM1
Osakabe, A.; Takizawa, Y.; Horikoshi, N.; Hatazawa, S.; Negishi, L.; Berger, F.; Kakutani, T.; Kurumizaka, H.
10.1101/2023.07.10.548306 — molecular biology — Posted on 2023-07-10
3215 A large-scale serological survey in pets from October 2020 through June 2021 in France shows significantly higher exposure to SARS-CoV-2 in cats
Fritz, M.; Elguero, E.; Becquart, P.; de Riols de Fonclare, D.; Garcia, D.; Beurlet, S.; Denolly, S.; Boson, B.; Rosolen, S. G.; Cosset, F.-L.; Briend-Marchal, A.; Legros, V.; Leroy, E. M.
10.1101/2022.12.23.521567 — microbiology — Posted on 2023-07-10
3216 Functional prediction of proteins from the human gut archaeome
Novikova, P. V.; Busi, S. B.; Probst, A. J.; May, P.; Wilmes, P.
10.1101/2023.02.01.526569 — microbiology — Posted on 2023-07-10
3217 Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection
Vu, M. N.; Alvarado, R. E.; Morris, D. R.; Lokugamage, K. G.; Zhou, Y.; Morgan, A. L.; Estes, L. K.; McLeland, A. M.; Schindewolf, C.; Plante, J. A.; Ahearn, Y. P.; Meyers, W. M.; Murray, J. T.; Weaver, S.; Walker, D. H.; Russell, W. K.; Routh, A. L.; Plante, K. S.; Menachery, V. D.
10.1101/2023.04.17.536926 — microbiology — Posted on 2023-07-10
3222 Cholesterol-associated Locus EHBP1 Protects against NASH Fibrosis
Ma, F.; Longo, M.; Huang, X.; Meroni, M.; Prakash, S.; Paolini, E.; Bhattacharya, D.; Wang, S.; Wang, X.; Mughal, S.; Hussain, S.; Anand, S.; Yurdagul, A.; Rom, O.; Dongiovanni, P.; Friedman, S.; Cai, B.
10.1101/2023.07.08.548218 — pathology — Posted on 2023-07-10
3226 A microRNA-based Johne's disease diagnostic predictive system: preliminary results
Capewell, P.; Lowe, A.; Athanasiadou, S.; Wilson, D.; Hanks, E.; Coultous, R.; Hutchings, M. R.; Palarea-Albaladejo, J.
10.1101/2023.07.07.548088 — bioinformatics — Posted on 2023-07-10
3227 RNA-to-image multi-cancer synthesis using cascaded diffusion models
Carrillo-Perez, F.; Pizurica, M.; Zheng, Y.; Nandi, T. N.; Madduri, R.; Shen, J.; Gevaert, O.
10.1101/2023.01.13.523899 — bioinformatics — Posted on 2023-07-10
3235 Simultaneous Recognition of Multiple Signals in Bacterial Outer Membrane Proteins Enhance Assembly and Maintain Membrane Integrity
Germany, E. M.; Thewasano, N.; Imai, K.; Maruno, Y.; Bamert, R. S.; Stubenrauch, C. J.; Dunstan, R. A.; Ding, Y.; Nakajima, Y.; Lai, X.; Webb, C. T.; Hidaka, K.; Tan, K. S.; Shen, H.-H.; Lithgow, T.; Shiota, T.
10.1101/2021.10.29.466387 — biochemistry — Posted on 2023-07-09
3239 A reference genome for the long-term kleptoplast-retaining sea slug Elysia crispata morphotype clarki
Eastman, K. E.; Pendleton, A. L.; Shaikh, M. A.; Suttiyut, T.; Ogas, R.; Tomko, P.; Gavelis, G.; Widhalm, J. R.; Wisecaver, J. H.
10.1101/2023.07.07.548153 — genomics — Posted on 2023-07-09
3241 Novel multifunctional glycan probes to elucidate specificities of diverse glycan recognition systems
Yu, J.; Decout, A. C.; Di Maio, A.; Chai, W.; Stehle, T.; Turnbull, B.; Feizi, T.; Liu, Y.
10.1101/2023.07.09.548266 — biochemistry — Posted on 2023-07-09
3243 DNA Recognition and Induced Genome Modification by a Hydroxymethyl-γ Tail-Clamp Peptide Nucleic Acid
Oyaghire, S. N.; Quijano, E.; Perera, D. R.; Mandl, H. K.; Saltzman, W. M.; Bahal, R.; Glazer, P. M.
10.1101/2023.07.08.548209 — genetics — Posted on 2023-07-09
3244 A Cryptic Basic Groove formed by Ubiquitin and Histone H3 Mediates the Selective Recognition of H2AK119Ub Nucleosomes by Synovial Sarcoma X Breakpoint 1 Protein
Tong, Z.; Ai, H.; Xu, Z.; He, K.; Chu, G.-c.; Shi, Q.; Deng, Z.; Xue, Q.; Sun, M.; Du, Y.; Liang, L.; Li, J.-B.; Pan, M.; LIU, L.
10.1101/2023.07.08.548231 — molecular biology — Posted on 2023-07-09
3245 Inhibition of an immunometabolic axis of mTORC1 activation extends mammalian healthspan
Widjaja, A. A.; Lim, W.-W.; Viswanathan, S.; Chothani, S.; Corden, B.; Goh, J. W. T.; Tan, J.; Pua, C. J.; Lim, R. H. T.; Singh, B. K.; Cibi, D. M.; Weber, S.; Lim, S. Y.; Adami, E.; George, B. L.; Sweeney, M.; Chen, X.; Tripathi, M.; Withers, D. J.; Hubner, N.; Schafer, S.; Ho, L.; Gil, J.; Carling, D.; Cook, S. A.
10.1101/2023.07.09.548250 — molecular biology — Posted on 2023-07-09
3247 Total infectome investigation of diphtheritic stomatitis in yellow-eyed penguins (Megadyptes antipodes) reveals a novel and abundant megrivirus
Wierenga, J. R.; Morgan, K. J.; Taylor, H.; Hunter, S.; Argilla, L. S.; Webster, T.; Lim, L.; Grimwood, R. M.; Schultz, H.; Jorge, F.; Bostina, M.; Burga, L.; Swindells-Wallace, P.; Holmes, E. C.; McInnes, K.; Geoghegan, J. L.
10.1101/2023.07.09.548243 — microbiology — Posted on 2023-07-09
3249 Cathelicidin downregulates neurotensin and substance P hippocampal levels
Flores, I. P.; Ariga, S. K.; Barbeiro, H. V.; Barbeiro, D. F.; Pinheiro Da Silva, F.
10.1101/2023.07.07.548146 — immunology — Posted on 2023-07-09
3250 Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.
Fagen, S.; Burgess, J. D.; Lim, M.; Amerna, D.; Kaya, Z. B.; Faroqi, A. H.; Perisetla, P.; DeMeo, N. N.; Stojkovska, I.; Quiriconi, D. J.; Mazzulli, J. R.; Delenclos, M.; Boschen, S. L.; McLean, P. J.
10.1101/2023.07.06.547988 — neuroscience — Posted on 2023-07-09
3253 Bio-optical signatures of insitu photosymbionts predict bleaching severity prior to thermal stress in the Caribbean coral species Acropora palmata
Hoadley, K.; Lowry, S.; McQuagge, A.; Dalessandri, S.; Lockridge, G.; Karabelas, E.; Klepac, C. N.; Kenkel, C. D.; Muller, E.
10.1101/2023.07.06.547971 — physiology — Posted on 2023-07-09
3254 Hypoxic memory of tumor intrinsic type I interferon suppression promotes breast cancer metastasis
Iriondo, O.; Mecenas, D.; Li, Y.; Chin, C. R.; Thomas, A.; Amzaleg, Y.; Moriarty, A.; Ortiz, V.; MacKay, M.; Dickerson, A.; Lee, G.; Harotoonian, S.; Benayoun, B. A.; Smith, A. D.; Mason, C.; Roussos Torres, E.; Klotz, R.; Yu, M.
10.1101/2022.05.12.491632 — cancer biology — Posted on 2023-07-09
3255 A microRNA-based Johne's disease diagnostic predictive system: preliminary results
Capewell, P.; Lowe, A.; Athanasiadou, S.; Wilson, D.; Hanks, E.; Coultous, R.; Hutchings, M. R.; Palarea-Albaladejo, J.
10.1101/2023.07.07.548088 — bioinformatics — Posted on 2023-07-09
3256 SpaceANOVA: Spatial co-occurrence analysis of cell types in multiplex imaging data using point process and functional ANOVA
Seal, S.; Neelon, B.; Angel, P.; O'Quinn, E.; Hill, E.; Vu, T.; Ghosh, D.; Mehta, A.; Wallace, K.; Alekseyenko, A. V.
10.1101/2023.07.06.548034 — bioinformatics — Posted on 2023-07-09
3262 Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail
Sexton, J. A.; Potchernikov, T.; Casanova-Sepulveda, G.; Cao, W.; Lou, H. J.; Boggon, T. J.; De La Cruz, E. M.; Turk, B. E.
10.1101/2023.06.30.547189 — molecular biology — Posted on 2023-07-09
3263 The Lion's Share: Implications of carnivore diet on endangered herbivores in Tsavo
King, E.; Chakrabarti, S.; Lala, F.; Nyaga, S.; Waiguchu, G.; Chiyo, P. I.; Kimaile, J.; Moller, R.; Omondi, P.; Morris, A.; Bump, J.
10.1101/2023.07.08.548222 — ecology — Posted on 2023-07-09
3264 Calcium and Integrin-binding protein 2 (CIB2) controls force sensitivity of the mechanotransducer channels in cochlear outer hair cells
Aristizabal-Ramirez, I.; Dragich, A. K.; Giese, A. P. J.; Zuluaga-Osorio, K. S.; Watkins, J.; Davies, G. K.; Hadi, S. E.; Riazuddin, S.; Vander Kooi, C. W.; Ahmed, Z. M.; Frolenkov, G. I.
10.1101/2023.07.09.545606 — neuroscience — Posted on 2023-07-09
3270 DataPLAN: a web-based data management plan generator for the plant sciences
Zhou, X.-R.; Beier, S.; Brilhaus, D.; Rodrigues, C. M.; Muehlhaus, T.; von Suchodoletz, D.; Twyman, R. M.; Usadel, B.; Kranz, A.
10.1101/2023.07.07.548147 — plant biology — Posted on 2023-07-09
3271 Social and genetic diversity in first farmers of central Europe
Gelabert, P.; Bickle, P.; Hofmann, D.; Teschler-Nicola, M.; Anders, A.; Huang, X.; Olalde, I.; Fournier, R.; Ringbauer, H.; Akbari, A.; Cheronet, O.; Lazaridis, I.; Broomandkhoshbacht, N.; Fernandes, D. M.; Buttinger, K.; Callan, K.; Candilio, F.; Bravo, G.; Curtis, E.; Ferry, M.; Keating, D.; Freilich, S.; Kearns, A.; Harney, E.; Lawson, A. M.; Mandl, K.; Michel, M.; Oberreiter, V.; Oppenheimer, J.; Sawyer, S.; Schattke, C.; Ozdogan, K. T. T.; Qiu, L.; Workman, N.; Zalzala, F.; Mallick, S.; Mah, M.; Micco, A.; Pieler, F.; Pavuk, J.; Lazar, C.; Skrivanko, M. K.; Slaus, M.; Bedic, Z.; Novotny,
10.1101/2023.07.07.548126 — genetics — Posted on 2023-07-09
3272 Spatial organization and function of RNA molecules within phase-separatedcondensates are controlled by Dnd1
Raz, E.; Westerich, K. J.; Tarbashevich, K.; Schick, J.; Gupta, A.; Zhu, M.; Hull, K.; Romo, D.; Zeuschner, D.; Goudarzi, M.; Gross-Thebing, T.
10.1101/2023.07.09.548244 — cell biology — Posted on 2023-07-09
3273 Polygenic Risk Score Associates with Atherosclerotic Plaque Characteristics at Autopsy
Cornelissen, A.; Gadhoke, N.; Ryan, K. A.; Hodonsky, C. J.; Mitchell, R. N.; Bihlmeyer, N. A.; Duong, T.; Chen, Z.; Dikongue, A.; Sakamoto, A.; Sato, Y.; Kawakami, R.; Mori, M.; Kawai, K.; Fernandez, R.; Ghosh, S. K. B.; Braumann, R.; Abebe, B.; Kutys, R.; Kutyna, M. D.; Romero, M. E.; Kolodgie, F.; Miller, C. L.; Hong, C. C.; Grove, M. L.; Brody, J. A.; Sotoodehnia, N.; Arking, D. E.; Schunkert, H.; Mitchell, B. D.; Guo, L.; Virmani, R.; Finn, A. V.
10.1101/2023.07.05.547891 — genetics — Posted on 2023-07-09
3274 Molossus molossus bats encompass at least two distinct genera of totivirus-like
Leal, E.; Couto, R. d. S.; Ramos, E. d. S. F.; Abreu, W. U.; Rodrigues, L. R. R.; Marinho, L. F.; dos Santos Morais, V.; Villanova, F.; Pandey, R. P.; Deng, X.; Delwart, E.; da Costa, A. C.
10.1101/2023.07.07.548100 — microbiology — Posted on 2023-07-09
3276 National seroprevalence and risk factors of bluetongue virus in domestic ruminants in Peru
Navarro-Mamani, D. A.; Jurado Pucllas, J.; Vargas-Calla, A.; Ponce Dextre, K.; Zarate Quispe, Y.; Murga-Moreno, C. A.; Perez C., I.; Villacaqui A., R.; Ara G., M.; Incil, E.; Ortiz, P.; Geronimo, H. R.
10.1101/2023.07.06.548015 — microbiology — Posted on 2023-07-09
3277 Direct Entorhinal Control of CA1 Temporal Coding
Guardamagna, M.; Chadney, O. M. T.; Stella, F.; Zhang, Q.; Kentros, C.; Battaglia, F. P.
10.1101/2023.05.27.542579 — neuroscience — Posted on 2023-07-09
3283 Direct optical measurement of intra-molecular distances down to the Angstrom scale
Sahl, S. J.; Matthias, J.; Inamdar, K.; Khan, T. A.; Weber, M.; Becker, S.; Griesinger, C.; Broichhagen, J.; Hell, S. W.
10.1101/2023.07.07.548133 — biophysics — Posted on 2023-07-09
3284 Pan-cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics
Wang, J.; Yu, W.; DAnna, R.; Przybyla, A.; Wilson, M.; Sung, M.; Bullen, J.; Hurt, E.; DAngelo, G.; Sidders, B.; Lai, Z.; Zhong, W.
10.1101/2023.01.23.525265 — bioinformatics — Posted on 2023-07-09
3288 Peripheral positioning of lysosomes supports melanoma aggressiveness
Jerabkova-Roda, K.; Mousson, A.; Peralta, M.; Karali, R.; Justiniano, H.; Lisii, L.-M.; Carl, P.; Asokan, N.; Busnelli, I.; Larnicol, A.; Lefebvre, O.; Lachuer, H.; Pichot, A.; Stemmelen, T.; Molitor, A.; Hirschler, A.; Delalande, F.; Sick, E.; Carapito, R.; Carapito, C.; Hyenne, V.; Schauer, K.; Ronde, P.; GOETZ, J. G.
10.1101/2023.07.07.548108 — cell biology — Posted on 2023-07-09
3290 Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State
Svensson, B.; Nitu, F. R.; Rebbeck, R. T.; McGurran, L. M.; Oda, T.; Thomas, D. D.; Bers, D. M.; Cornea, R. L.
10.1101/2023.07.07.548138 — biophysics — Posted on 2023-07-09
3292 Single-cell T cell receptor sequencing of paired tissue and blood samples reveals clonal expansion of CD8+ effector T cells in patients with calcific aortic valve disease
Bartoli-Leonard, F.; Chelvanambi, S.; Pham, T.; Turner, M. E.; Blaser, M. C.; Caputo, M.; Aikawa, M.; Pang, A.; Muehlschlegel, J.; Aikawa, E.
10.1101/2023.07.08.548203 — immunology — Posted on 2023-07-08
3293 Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations
Pass, T.; Ricke, K. M.; Hofmann, P.; Chowdhury, R.; Nie, Y.; Chinnery, P. F.; Endepols, H.; Neumaier, B.; Carvalho, A.; Rigoux, L.; Steculorum, S.; Prudent, J.; Riemer, T.; Aswendt, M.; Brachvogel, B.; Wiesner, R. J.
10.1101/2023.07.07.547791 — neuroscience — Posted on 2023-07-08
3296 ZEB1 shapes AML immunological niches suppressing CD8 T-cell activity while fostering Th17 cell expansion.
Bassani, B.; Simonetti, G.; Cancila, V.; Ciciarello, M.; Piva, A.; Chiodoni, C.; Lecis, D.; Gulino, A.; Fonzi, E.; Botti, L.; Portararo, P.; Costanza, M.; Schwaller, J.; Tzankov, A.; Ponzoni, M.; Ciceri, F.; Bolli, N.; Curti, A.; Tripodo, C.; Colombo, M. P.; Sangaletti, S.
10.1101/2023.07.08.548195 — immunology — Posted on 2023-07-08
3297 Skin mesenchymal niches maintain and protect AML-initiating stem cells
Sandhow, L.; Cai, H.; Leonard, E.; Xiao, P.; Tomaipitinca, L.; Mansson, A.; Kondo, M.; Sun, X.; Johansson, A.-S.; Tryggvason, K.; Kasper, M.; Jaras, M.; QIAN, H.
10.1101/2022.05.20.491183 — cancer biology — Posted on 2023-07-08
3298 Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
Chavdoula, E.; Anastas, V.; La Ferlita, A.; Aldana, J.; Carota, G.; Spampinato, M.; Soysal, B.; Cosentini, I.; Parashar, S.; Sircar, A.; Sehgal, L.; Freitas, M. A.; Tsichlis, P. N.
10.1101/2023.07.07.548031 — cancer biology — Posted on 2023-07-08
3301 Reprogramming method does not impact the neuronal differentiation potential of 16p11.2 deletion patient iPSCs
Wells, M. F.; Guss, E.; Zhou, H.; Sun, B.; Martinez, H.; Akopian, V.; Noggle, S.; Paull, D.; Moore, J.; Sheldon, M.; Sommer, J.; Benedetti, M.; Meissner, A.; Eggan, K.
10.1101/2023.07.07.548182 — developmental biology — Posted on 2023-07-08
3307 Structural basis for lipid transfer by the ATG2A-ATG9A complex
Wang, Y.; Dahmane, S.; Ti, R.; Mai, X.; Zhu, L.; Carlson, L.-A.; Stjepanovic, G.
10.1101/2023.07.08.548186 — biochemistry — Posted on 2023-07-08
3308 A framework for Frizzled-G protein coupling and implications to the Wnt-PCP signaling pathways
Zhang, Z.; Lin, X.; Wei, L.; Wu, Y.; Xu, L.; Wu, L.; Wei, X.; Wang, A.; Zhao, S.; Zhu, X.; Xu, F.
10.1101/2023.07.08.548223 — biochemistry — Posted on 2023-07-08
3309 Multivalent dynamic colocalization of avian influenza polymerase and nucleoprotein by intrinsically disordered ANP32A reveals the molecular basis of human adaptation
Camacho-Zarco, A. R.; Yu, L.; Krischuns, T.; Dedeoglu, S.; Maurin, D.; Bouvignies, G.; Crepin, T.; Ruigrok, R. W. H.; Cusack, S.; Naffakh, N.; Blackledge, M.
10.1101/2023.07.08.548184 — biochemistry — Posted on 2023-07-08
3310 α-carboxysome size is controlled by the disordered scaffold protein CsoS2
Oltrogge, L. M.; Chen, A. W.; Chaijarasphong, T.; Turnsek, J. B.; Savage, D. F.
10.1101/2023.07.07.548173 — biochemistry — Posted on 2023-07-08
3312 Epigenetic variation causes heritable variation in complex traits in the mollusk Biomphalaria glabrata, vector of the human parasite Schistosoma mansoni
Luviano, N.; Lopez, M.; Gawehns, F.; Haegeman, B.; Mouginot, P.; Chaparro, C.; Arimondo, P. B.; Pujol, B.; Cosseau, C.; Grunau, C.
10.1101/2023.07.08.548202 — ecology — Posted on 2023-07-08
3314 ComBat Harmonization: Empirical Bayes versus Fully Bayes Approaches
Reynolds, M.; Chaudhary, T.; Torbati, M. E.; Tudorascu, D. L.; Batmanghelich, K.
10.1101/2022.07.13.499561 — neuroscience — Posted on 2023-07-08
3315 Affinity hierarchies underlie the co-assembly of nucleolar and heterochromatin condensates in Drosophila embryos
Rajshekar, S.; Adame-Arana, O.; Bajpai, G.; Lin, K.; Colmenares, S.; Safran, S.; Karpen, G. H.
10.1101/2023.07.06.547894 — cell biology — Posted on 2023-07-08
3317 Integrative spatial analysis reveals a multi-layered organization of glioblastoma
Greenwald, A. C.; Darnell, N. G.; Hoefflin, R.; Simkin, D.; Gonzalez-Castro, L. N.; Mount, C.; Hirsch, D.; Nomura, M.; Talpir, T.; Kedmi, M.; Goliand, I.; Medici, G.; Li, B.; Keren-Shaul, H.; Weller, M.; Addadi, Y.; Neidert, M. C.; Suva, M. L.; Tirosh, I.
10.1101/2023.07.06.547924 — cancer biology — Posted on 2023-07-08
3322 Human complement Factor H and Properdin act as soluble pattern recognition receptors and differentially modulate SARS-CoV-2 Infection
Beirag, N.; Varghese, P. M.; Kumar, C.; Idicula-Thomas, S.; Mayora Neto, M.; Khan, H. A.; Sim, R. B.; Madan, T.; Temperton, N. J.; Kishore, U.
10.1101/2023.07.07.548083 — immunology — Posted on 2023-07-08
3324 Diffusion model of delipidation in biological sample clearing
Han, J.; Liu, X.; Hou, X.; Zhong, Y.; Chen, Z.; Yang, Z.; Jiang, T.
10.1101/2023.06.18.545453 — neuroscience — Posted on 2023-07-08
3325 Multimodal imaging for validation and optimization of ion channel-based chemogenetics in nonhuman primates
Hori, Y.; Nagai, Y.; Hori, Y.; Oyama, K.; Mimura, K.; Hirabayashi, T.; Inoue, K.-i.; Fujinaga, M.; Zhang, M.-R.; Takada, M.; Higuchi, M.; Minamimoto, T.
10.1101/2023.07.06.547946 — neuroscience — Posted on 2023-07-08
3326 Deviance detection in subthalamic neural population responses to natural stimuli in bats
Wetekam, J.; Hechavarria, J. C.; Lopez-Jury, L.; Gonzalez-Palomares, E.; Koessl, M.
10.1101/2023.07.06.547961 — neuroscience — Posted on 2023-07-08
3328 From colonial clusters to colonial "sheaths": analysis of Microcystis morphospecies in mesocosm by imaging flow cytometry
Zhumakhanova, A.; Mirasbekov, Y.; Malashenkov, D.; Davidson, T. A.; Levi, E. E.; Jeppesen, E.; Barteneva, N. S.
10.1101/2023.07.07.545121 — ecology — Posted on 2023-07-08
3334 The role of genetically distinct central amygdala neurons in appetitive and aversive responding assayed with a novel dual valence operant conditioning paradigm.
Dorofeikova, M.; Stelly, C. E.; Duong, A.; Basavanhalli, S.; Bean, E.; Weissmuller, K.; Sifnugel, N.; Resendez, A.; Corey, D. M.; Tasker, J. G.; Fadok, J. P.
10.1101/2023.07.07.547979 — neuroscience — Posted on 2023-07-08
3338 A Novel Drosophila Model to Investigate Adipose Tissue Macrophage Infiltration (ATM) and Obesity highlights the Therapeutic Potential of Attenuating Eiger/TNF Signaling to Ameliorate Insulin Resistance and ATM.
Mirzoyan, Z.; Valenza, A. M.; Zola, S.; Bonfanti, C.; Arnaboldi, L.; Ferrari, N.; Pollard, J.; Lupi, V.; Cassinelli, M.; Frattaroli, M.; Sahin, M.; Pasini, M. E.; Bellosta, P.
10.1101/2023.07.06.548016 — physiology — Posted on 2023-07-08
3339 SEM2: A computational framework to model multiscale mechanics with subcellular elements
Chattaraj, S.; Torre, M.; Kalcher, C.; stukowski, A.; Morganti, S.; Reali, A.; Pasqualini, F.
10.1101/2023.07.07.548118 — bioengineering — Posted on 2023-07-08
3340 Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation
Wu, D.; Zhang, X.; Zimmerly, K.; Wang, R.; Livingston, A.; Iwawaki, T.; Kumar, A.; Wu, X.; Mandell, M.; Liu, M.; Yang, X. A.
10.1101/2023.06.30.547286 — immunology — Posted on 2023-07-08
3341 Dominance formulation in multi-component binary phase equilibria
Qian, D.; Ausserwoger, H.; Sneideris, T.; Pappu, R. V.; Knowles, T.
10.1101/2023.06.12.544666 — biophysics — Posted on 2023-07-08
3346 Multiple TonB Homologs are Important for Carbohydrate Utilization by Bacteroides thetaiotaomicron
Pollet, R. M.; Foley, M. H.; Kumar, S. S.; Elmore, A.; Jabara, N. T.; Venkatesh, S.; Vasconcelos Pereira, G.; Martens, E.; Koropatkin, N. M.
10.1101/2023.07.07.548152 — microbiology — Posted on 2023-07-07
3355 Selective endocytic uptake of targeted liposomes occurs within a narrow range of liposome diameter
Ashby, G.; Keng, K. E.; Hayden, C. C.; Gollapudi, S.; Houser, J. R.; Jamal, S.; Stachowiak, J.
10.1101/2023.07.06.548000 — bioengineering — Posted on 2023-07-07
3356 Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs
Corey, D. R.; Johnson, K. R.; Hu, J.; Kilikevicius, A.; Hofman, C.; Liu, Y.; Aguilar, S.; Han, Y.; Graswich, C.; Wang, T.; Wescott, J.; Brekken, R. A.; Peng, L.; Karagkounis, G.
10.1101/2023.07.07.548119 — biochemistry — Posted on 2023-07-07
3357 Plasma Oxylipin Profiling by High Resolution Mass Spectrometry Reveal Signatures of Inflammation and Hypermetabolism in Amyotrophic Lateral Sclerosis
Chaves-Filho, A. B.; Diniz, L. S.; Santos, R. S.; Lima, R. S.; Oreliana, H.; Pinto, I. F. D.; Dantas, L. S.; Inague, A.; Faria, R. L.; Medeiros, M. H. G.; Glezer, I.; Festuccia, W. T.; Yoshinaga, M. Y.; Miyamoto, S.
10.1101/2023.07.07.547101 — biochemistry — Posted on 2023-07-07
3358 A single genetic locus lengthens deer mouse burrows via motor pattern evolution
Harringmeyer, O. S.; Hu, C. K.; Metz, H. C.; Mihelic, E. L.; Rosher, C.; Sanguinetti-Scheck, J. I.; Hoekstra, H. E.
10.1101/2023.07.03.547545 — evolutionary biology — Posted on 2023-07-07
3368 Complex Sphingolipid Profiling and Identification of an Inositol Phosphorylceramide Synthase in Dictyostelium discoideum
Listian, S. A.; Kol, M.; Ufelmann, E.; Eising, S.; Froehlich, F.; Walter, S.; Holthuis, J. C. M.; Barisch, C.
10.1101/2023.07.07.548115 — cell biology — Posted on 2023-07-07
3371 The Prokaryotic and Eukaryotic Microbiome of Pacific Oyster Spat is Shaped by Ocean Warming but not Acidification
Zhong, K. X.; Chan, A. M.; Collicutt, B.; Daspe, M.; Finke, J. F.; Foss, M.; Green, T. J.; Harley, C. D. G.; Hesketh, A. V.; Miller, K. M.; Otto, S. P.; Rolheiser, K.; Saunders, R.; Sutherland, B. J. G.; Suttle, C. A.
10.1101/2023.07.07.548145 — microbiology — Posted on 2023-07-07
3372 Bacterial vampirism mediated through chemotaxis
Glenn, S. J.; Gentry-Lear, Z.; Shavlik, M.; Harms, M. J.; Baylink, A.
10.1101/2023.07.07.548164 — microbiology — Posted on 2023-07-07
3373 A conserved antigen induces respiratory Th17-mediated serotype-independent protection against pneumococcal superinfection
Liu, X.; Van Maele, L.; Matarazzo, L.; Soulard, D.; Alves Duarte da Silva, V.; de Bakker, V.; Denereaz, J.; Bock, F. P.; Taschner, M.; Gruber, S.; Nizet, V.; Sirard, J.-C.; Veening, J.-W.
10.1101/2023.07.07.548156 — microbiology — Posted on 2023-07-07
3376 Exploring alternative quorum sensing model structures and quorum quenching strategies
Cimolato, C.; Bellato, M.; Selvaggio, G.; Marchetti, L.; Giordano, G.; Schenato, L.
10.1101/2023.07.07.548074 — synthetic biology — Posted on 2023-07-07
3377 Antisense transcription and PRC2 repression function in parallel during vernalization
Nielsen, M.; Menon, G.; Zhao, Y.; Mateo-Bonmati, E.; Wolff, P.; Zhou, S.; Howard, M.; Dean, C.
10.1101/2023.07.07.547987 — molecular biology — Posted on 2023-07-07
3380 Naturally segregating genetic variants contribute to thermal tolerance in a D. melanogaster model system.
Williams-Simon, P. A.; Oster, C.; Moaton, J. A.; Ghidey, R.; Ngoma, E.; Middleton, K. M.; King, E. G.
10.1101/2023.07.06.547110 — evolutionary biology — Posted on 2023-07-07
3381 Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f
Gusach, A.; Lee, Y.; Khoshgrudi, A. N.; Mukhaleva, E.; Ma, N.; Koers, E. J.; Chen, Q.; Edwards, P.; Huang, F.; Kim, J.; Mancia, F.; Veprintsev, D. J.; Vaidehi, N.; Weyand, S.; Tate, C. G.
10.1101/2023.07.07.547762 — molecular biology — Posted on 2023-07-07
3382 NECing goes: flexibility of the herpesvirus nuclear egress complex
Prazak, V.; Mironova, Y.; Vasishtan, D.; Hagen, C.; Laugks, U.; Jensen, Y.; Sanders, S.; Heumann, J. M.; Bosse, J. B.; Klupp, B.; Mettenleiter, T. C.; Grange, M.; Grünewald, K.
10.1101/2023.07.07.547920 — microbiology — Posted on 2023-07-07
3383 First Eurasian cases of SARS-CoV-2 seropositivity in a free-ranging urban population of wild fallow deer
Purves, K.; Brown, H.; Haverty, R.; Ryan, A.; Griffin, L.; McCormack, J.; O'Reilly, S. R.; Mallon, P. W.; Gautier, V.; Cassidy, J. P.; Fabre, A.; Carr, M. J.; Gonzalez, G.; Ciuti, S.; Fletcher, N.
10.1101/2023.07.07.547941 — microbiology — Posted on 2023-07-07
3385 Establishing thresholds for cytokine storm and defining their relationship to disease severity in respiratory viral infections
Souquette, A.; Crawford, J. C.; Wolf, J.; Blair, A.; Agrawal, M.; Boywid, L.; McNair, K.; Hysmith, N. D.; Hundman, C.; Bahadoran, A.; Arnold, S. R.; SJTRC Study Team, ; Smallwood, H.; Green, A.; Thomas, P. G.
10.1101/2023.07.06.548022 — immunology — Posted on 2023-07-07
3386 Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.
Carrillo, J.; Avila-Nieto, C.; Vergara-Alert, J.; Amengual-Rigo, P.; Ainsua-Enrich, E.; Brustolin, M.; Rodriguez de la Concepcion, M. L.; Pedreno-Lopez, N.; Rodon, J.; Urrea, V.; Pradenas, E.; Marfil, S.; Ballana, E.; Riveira-Munoz, E.; Perez, M.; Roca, N.; Tarres-Freixas, F.; Carabelli, J.; Cantero, G.; Pons-Grifols, A.; Rovirosa, C.; Aguilar-Gurrieri, C.; Ortiz, R.; Barajas, A.; Trinite, B.; Lepore, R.; Munoz-Basagoiti, J.; Perez-Zsolt, D.; Izquierdo-Useros, N.; Valencia, A.; Blanco, J.; Clotet, B.; Guallar, V.; Segales, J.
10.1101/2023.07.07.548077 — immunology — Posted on 2023-07-07
3389 SPAT: Surface Protein Annotation Tool
Spinella, J.-F.; Theret, L.; Aubert, L.; Audemard, E.; Boucher, G.; Pfammatter, S.; Bonneil, E.; Bordeleau, M.-E.; Thibault, P.; Hebert, J.; Roux, P. P.; Sauvageau, G.
10.1101/2023.07.07.547075 — bioinformatics — Posted on 2023-07-07
3390 Single cell susceptibility to SARS-CoV-2 infection is driven by variable cell states
Reffsin, S.; Miller, J.; Ayyanathan, K.; Dunagin, M. C.; Jain, N.; Schultz, D. C.; Cherry, S.; Raj, A.
10.1101/2023.07.06.547955 — bioengineering — Posted on 2023-07-07
3391 In vitro broad-spectrum antiviral activity of MIT-001, a mitochondria-targeted reactive oxygen species scavenger, against severe acute respiratory syndrome coronavirus 2 and multiple zoonotic viruses
Lim, T.; Rajoriya, S.; Kim, B.; Prayitno, S. p.; Natasha, A.; Park, J.; Jang, N. Y.; Im, H.; Shim, H. S.; Yoo, J.; Kim, J. W.; Lee, E.-W.; Shin, H. J.; Kim, S. H.; Kim, W.-K.
10.1101/2023.07.06.547945 — microbiology — Posted on 2023-07-07
3392 CLIPB4 is a central node in the protease network that regulates humoral immunity in Anopheles gambiae mosquitoes
Zhang, X.; Zhang, S.; Kuang, J.; Sellens, K. A.; Morejon, B.; Saab, S. A.; Metto, E. M.; Li, M.; Osta, M.; An, C.; Culbertson, C. T.; Scoglio, C. M.; Michel, K.
10.1101/2023.07.07.545904 — immunology — Posted on 2023-07-07
3393 Enhanced cellular longevity arising from environmental fluctuations
Liu, Y.; Zhou, Z.; Wu, S.; Ni, G.; Zhang, A.; Tsimring, L. S.; Hasty, J.; Hao, N.
10.1101/2023.07.05.547867 — systems biology — Posted on 2023-07-07
3395 Maternal Under-Nutrition During Pregnancy Alters the Molecular Response to Over-Nutrition in Multiple Organs and Tissues in Juvenile Offspring
Cox, L. A.; Puppala, S.; Chan, J.; Riojas, A. M.; Lange, K. J.; Birnbaum, S.; Dick, E. J.; Comuzzie, A. G.; Nijland, M. J.; Li, C.; Nathanielsz, P. W.; Olivier, M. M.
10.1101/2023.07.07.548121 — systems biology — Posted on 2023-07-07
3396 Outer membrane vesicles as realistic models of bacterial membranes in interaction studies by Surface Plasmon Resonance
Bril'kov, M.; Stenbakk, V.; Jakubec, M.; Vasskog, T.; Kristoffersen, T.; Cavanagh, J. P.; Ericson, J. U.; Isaksson, J.; Flaten, G. E.
10.1101/2023.07.07.548064 — molecular biology — Posted on 2023-07-07
3400 Global motor dynamics - Invariant neural representations of motor behavior in distributed brain-wide recordings
Ottenhoff, M. C.; Verwoert, M.; Goulis, S.; Wagner, L.; van Dijk, J. P.; Kubben, P. L.; Herff, C.
10.1101/2023.07.07.548122 — neuroscience — Posted on 2023-07-07
3402 Abscisic acid inhibits germination of Striga seeds and is released by them as a rhizospheric signal providing competitive advantage and supporting host infestation
Jamil, M.; Alagoz, Y.; Wang, J. Y.; Chen, G.-T. E.; Berqdar, L.; Kharbatia, N. M.; Beltran, J. C. M.; Kuijer, H. N. J.; Al-Babili, S.
10.1101/2023.07.06.548005 — plant biology — Posted on 2023-07-07
3405 Low- and high-grade glioma endothelial cells differentially regulate tumor growth
Muthukrishnan, S. D.; Qi, H.; Wang, D.; Elahi, L.; Pham, A.; Alvarado, A. G.; Li, T.; Gao, F.; Kawaguchi, R.; Lai, A.; Kornblum, H. I.
10.1101/2023.07.07.548125 — cancer biology — Posted on 2023-07-07
3409 The fate of sulfamethoxazole and trimethoprim in a micro-aerated anaerobic membrane bioreactor: implications for antibiotic resistance spreading
Piaggio, A. L.; Mittapalli, S.; Calderon-Franco, D.; Weissbrodt, D. G.; van Lier, J. B.; de Kreuk, M. K.; Lindeboom, R. E. F.
10.1101/2023.07.05.547898 — bioengineering — Posted on 2023-07-07
3410 Low intensity mechanical signals promote proliferation in a cell-specific manner: Tailoring a non-drug strategy to enhance biomanufacturing yields.
Chan, M. L.; Strait, L.; Ashdown, C.; Pasumarthy, S.; Hassan, A.; Crimarco, S.; Singh, C.; Patel, V.; Pagnotti, G. M.; Khan, O.; Uzer, G.; Rubin, C.
10.1101/2023.07.05.547864 — bioengineering — Posted on 2023-07-07
3413 Neuromorphic Cytometry: Implementation on cell counting and size estimation
Zhang, Z.; Xu, Z.; McGuire, H.; Essam, C.; Nicholson, A.; Hamilton, T. J.; Li, J.; Eshraghian, J. K.; Yong, K.-T.; Vigolo, D.; Kavehei, O.
10.1101/2023.07.06.548044 — cell biology — Posted on 2023-07-07
3414 Manipulation of Bacterial ROS Production Leads to Self-escalating DNA Damage and Resistance-resistant Lethality for Intracellular Mycobacteria
Song, J.; Wang, M.; Tao, H.; Yang, A.; Zhu, Z.; Bai, S.; Luo, M.; Xu, J.; Liu, X.; Sun, Y.; Hu, P.; Wong, W.-L.; Li, F.; Chen, Y.; Cai, Q.; Liu, H.; Huang, S.-Y.; Su, Z.; Feng, X.
10.1101/2023.07.07.548098 — microbiology — Posted on 2023-07-07
3415 A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
Bonetti, L.; Horkova, V.; Longworth, J.; Guerra, L.; Kurniawan, H.; Franchina, D. G.; Soriano-Baguet, L.; Grusdat, M.; Spath, S.; Koncina, E.; Ewen, A.; Binsfeld, C.; Verscheuren, C.; Gerardy, J.-J.; Kobayashi, T.; Dostert, C.; Farinelle, S.; Harm, J.; Chen, Y.; Harris, I. S.; Lang, P. A.; Vasiliou, V.; Waisman, A.; Letellier, E.; Becher, B.; Mittelbronn, M.; Brenner, D.
10.1101/2023.07.06.547932 — immunology — Posted on 2023-07-07
3417 Neural subspaces of imagined movements in parietal cortex remain stable over several years in humans.
Bashford, L.; Rosenthal, I. A.; Kellis, S.; Bjanes, D.; Pejsa, K.; Brunton, B. W.; Andersen, R.
10.1101/2023.07.05.547767 — neuroscience — Posted on 2023-07-07
3418 Revealing abrupt transitions from goal-directed to habitual behavior
Moore, S.; Wang, Z.; Zhu, Z.; Sun, R.; Lee, A.; Charles, A.; Kuchibhotla, K. V.
10.1101/2023.07.05.547783 — neuroscience — Posted on 2023-07-07
3420 Epigenetic and neural correlates of selective social attention across adulthood
Puglia, M. H.; Lynch, M. E.; Nance, M. G.; Connelly, J. J.; Morris, J. P.
10.1101/2023.07.06.547939 — neuroscience — Posted on 2023-07-07
3423 A growth chart of brain function from infancy to adolescence based on electroencephalography
Iyer, K. K.; Roberts, J. A.; Waak, M.; Vogrin, S. J.; Kevat, A.; Chawla, J.; Haataja, L. M.; Lauronen, L.; Vanhatalo, S.; Stevenson, N. J.
10.1101/2023.07.07.548062 — neuroscience — Posted on 2023-07-07
3429 Semi-supervised integration of single-cell transcriptomics data
Andreatta, M.; Herault, L.; Gueguen, P.; Gfeller, D.; Berenstein, A. J.; Carmona, S. J.
10.1101/2023.07.07.548105 — bioinformatics — Posted on 2023-07-07
3430 SpaceANOVA: Spatial co-occurrence analysis of cell types in multiplex imaging data using point process and functional ANOVA
Seal, S.; Neelon, B.; Angel, P.; O'Quinn, E.; Hill, E.; Vu, T.; Ghosh, D.; Mehta, A.; Wallace, K.; Alekseyenko, A. V.
10.1101/2023.07.06.548034 — bioinformatics — Posted on 2023-07-07
3432 Accelerated computations for iterative-solver techniques in single-step BLUP models
Freudenberg, A.; Vandenplas, J.; Schlather, M.; Pook, T.; Evans, R.; ten Napel, J.
10.1101/2023.07.06.547949 — bioinformatics — Posted on 2023-07-07
3435 Optimizing CRE and PhiC31 mediated recombination in Aedes aegypti
Carabajal Paladino, L. Z.; Wilson, R.; Tng, P. Y. L.; Dhokiya, V.; Keen, E.; Cuber, P.; Larner, W.; Rooney, S.; Nicholls, M.; Uglow, A.; Williams, L.; Anderson, M. A. E.; Basu, S.; Leftwich, P. T.; Alphey, L.
10.1101/2023.07.07.548128 — bioengineering — Posted on 2023-07-07
3437 SEM2: A computational framework to model multiscale mechanics with subcellular elements
Chattaraj, S.; Torre, M.; Kalcher, C.; stukowski, A.; Morganti, S.; Reali, A.; Pasqualini, F.
10.1101/2023.07.07.548118 — bioengineering — Posted on 2023-07-07
3441 Topological stratification of continuous genetic variation in large biobanks
Diaz-Papkovich, A.; Zabad, S.; Ben-Eghan, C.; Anderson-Trocme, L.; Femerling, G.; Nathan, V.; Patel, J.; Gravel, S.
10.1101/2023.07.06.548007 — genomics — Posted on 2023-07-07
3445 Massive RNA editing in ascetosporean mitochondria
Yabuki, A.; Fujii, C.; Yazaki, E.; Tame, A.; Mizuno, K.; Obayashi, Y.; Takao, Y.
10.1101/2023.07.06.548043 — evolutionary biology — Posted on 2023-07-07
3447 Influence of Geographical Aspect and Topography on Canopy Openness in Tropical Rainforests of Sri Lanka along an Altitudinal Gradient
Madhumali, R. M. C.; Wahala, W. M. P. S. B.; Sanjeewani, H. K. N.; Samarasinghe, D. P.; De Costa, W. A. J. M.
10.1101/2023.07.06.547768 — ecology — Posted on 2023-07-07
3448 Filter-aided extracellular vesicle enrichment (FAEVEr)
Pauwels, J.; Van de Steene, T.; Van de Velde, J.; Eyckerman, S.; Gevaert, K.
10.1101/2023.07.06.547926 — cell biology — Posted on 2023-07-07
3449 Near infrared-light treatment alters mitochondrial homeostasis to induce senescence in breast cancer cells
Kalampouka, I.; Mould, R. R.; Botchway, S. W.; Mackenzie, A.; Nunn, A. V.; Thomas, E. L.; Bell, J. D.
10.1101/2023.07.06.547935 — cell biology — Posted on 2023-07-07
3455 Bile acids mediate liver-bone marrow crosstalk
Vitale, D.; Karimi Azardaryany, M.; Alipour Talesh, G.; Shahidi, M.; Ho, V.; Dervish, S.; Haryanto Jong, F. H.; Suoh, M.; George, J.; Esmaili, S.
10.1101/2023.07.05.546968 — immunology — Posted on 2023-07-07
3456 Single-cell transcriptomic analysis of NK cell dynamics in myeloma patients reveal persistent reduction of cytotoxic NK cells from diagnosis to relapse
Tahri, S.; de Jong, M. M. E.; Fokkema, C.; Papazian, N.; Kellermayer, Z.; Vermeulen, M.; Van Duin, M.; Van Beek, G.; Hoogenboezem, R.; Van De Woestijne, P.; Nasserinejad, K.; Saraci, E.; D'Agostino, M.; Gay, F.; Van Der Velden, V.; Sanders, M.; Zweegman, S.; Van De Donk, N.; Broijl, A.; Sonneveld, P.; Cupedo, T.
10.1101/2023.07.05.547295 — immunology — Posted on 2023-07-07
3458 Altered spread of large scale brain dynamics is influenced by cortical thickness organization in temporal lobe epilepsy: a MRI and hdEEG study
Duma, G. M.; Pellegrino, G.; Rabuffo, G.; Danieli, A.; Antoniazzi, L.; Vitale, V.; Scotto Opipari, R.; Bonanni, P.; Sorrentino, P.
10.1101/2023.07.05.547809 — neuroscience — Posted on 2023-07-07
3459 Directional Sensitivity of Cortical Neurons Towards TMS Induced Electric Fields
Weise, K.; Worbs, T. H.; Kalloch, B.; Souza, V. H.; Jaquier, A. T.; Van Geit, W.; Thielscher, A.; Knoesche, T. R.
10.1101/2023.07.06.547913 — neuroscience — Posted on 2023-07-07
3461 Rare GPR37L1 variants reveal potential roles in anxiety and migraine disorders
Breitwieser, G.; Cippitelli, A.; Wang, Y.; Pelletier, O.; Dershem, R.; Wei, J.; Toll, L.; Fakhoury, B.; Brunori, G.; Metpally, R.; Genetics Center, R.; Carey, D. J.; Robishaw, J. D.
10.1101/2023.07.05.547546 — neuroscience — Posted on 2023-07-07
3462 Multivariate and Regional Age-Related Change in Basal Ganglia Iron in Neonates
Cabral, L.; Calabro, F.; Foran, W.; Parr, A.; Ojha, A.; Rasmussen, J.; Ceschin, R.; Panigrahy, A.; Luna, B.
10.1101/2023.07.05.547821 — neuroscience — Posted on 2023-07-07
3464 Emotion-induced frontal α asymmetry predictsrelapse after discontinuation of antidepressantmedication
Berwian, I. M.; Troendle, M.; de Miquel, C.; Ziogas, A.; Stefanics, G.; Walter, H.; Stephan, K. E.; Huys, Q. J.
10.1101/2023.07.05.547831 — neuroscience — Posted on 2023-07-07
3467 Dimensional and Categorical Solutions to Parsing Depression Heterogeneity in a Large Single-Site Sample
Dunlop, K.; Grosenick, L.; Downar, J.; Vila-Rodriguez, F.; Gunning, F. M.; Daskalakis, Z.; Blumberger, D. M.; Liston, C.
10.1101/2023.07.05.547873 — neuroscience — Posted on 2023-07-07
3468 Validating models of TMS effects with concurrent TMS/fMRI
Petrov, P. I.; Vink, J.; Mandija, S.; van den Berg, N.; Dijkhuizen, R.; Neggers, S. F. W.
10.1101/2023.07.05.547836 — neuroscience — Posted on 2023-07-07
3474 Prolonged activity-deprivation causes pre- and postsynaptic compensatory plasticity at neocortical excitatory synapses
Wise, D.; Escobedo-Lozoya, Y.; Valakh, V.; Isaac, B.; Gao, E.; Greene, S.; Bhonsle, A.; Lei, L.; Cheng, X.; Van Hooser, S.; Nelson, S. B.
10.1101/2023.07.05.547850 — neuroscience — Posted on 2023-07-07
3475 Small molecule activation of m6A mRNA methylation as a novel approach for neuroprotection
Yu, L.-Y.; Selberg, S.; Teino, I.; Nam, J.; Ivanova, L.; Renzi, B.; Seli, N.; Kankuri, E.; Voutilainen, M. H.; Karelson, M.; Saarma, M.
10.1101/2023.07.05.547860 — neuroscience — Posted on 2023-07-07
3477 Mapping general anesthesia states based on electro-encephalogram transition phases
Loison, V.; Voskobiynyk, Y.; Lindquist, B.; Necula, D.; Longrois, D.; Paz, J. T.; Holcman, D.
10.1101/2023.07.06.547567 — neuroscience — Posted on 2023-07-07
3478 Induction of plant disease resistance by mixed oligosaccharide elicitors prepared from plant cell wall and crustacean shells
Pring, S.; Kato, H.; Imano, S.; Camagna, M.; Tanaka, A.; Kimoto, H.; Chen, P.; Shrotri, A.; Kobayashi, H.; Fukuoka, A.; Saito, M.; Suzuki, T.; Terauchi, R.; Sato, I.; Chiba, S.; Takemoto, D.
10.1101/2023.07.06.547984 — plant biology — Posted on 2023-07-07
3479 Independent component analysis (ICA) applied to dynamic oxygen-enhanced MRI (OE-MRI) for robust functional lung imaging at 3 T
Needleman, S. H.; Kim, M.; McClelland, J. R.; Naish, J. H.; Tibiletti, M.; O'Connor, J. P. B.; Parker, G. J. M.
10.1101/2023.07.05.547787 — physiology — Posted on 2023-07-07
3480 Ca2+-sensing receptor regulates neuronal excitability via Kv7 channel and Gi/o protein signalling
Chuinsiri, N.; Siraboriphantakul, N.; Kendall, L.; Yarova, P.; Nile, C. J.; Song, B.; Obara, I.; Durham, J.; Telezhkin, V.
10.1101/2023.07.07.548061 — physiology — Posted on 2023-07-07
3482 A machine learning approach for quantifying age-related histological changes in the mouse kidney.
Sheehan, S.; Mawe, S.; Chen, M.; Klug, J.; Ladiges, W. C.; Korstanje, R.; Mahoney, J. M.
10.1101/2023.07.07.548002 — pathology — Posted on 2023-07-07
3487 RamanSPy: An open-source Python package for integrative Raman spectroscopy data analysis
Georgiev, D.; Pedersen, S. V.; Xie, R.; Fernandez-Galiana, A.; Stevens, M. M.; Barahona, M.
10.1101/2023.07.05.547761 — bioinformatics — Posted on 2023-07-07
3490 Inference of host-pathogen interaction matrices from genome-wide polymorphism data
Maerkle, H.; John, S.; Metzger, L.; STOP-HCV Consortium, ; Ansari, M. A.; Pedergnana, V.; Tellier, A.
10.1101/2023.07.06.547816 — evolutionary biology — Posted on 2023-07-07
3491 Coffee microsporogenesis and related small interfering RNAs biosynthesis have a unique pattern among eudicots suggesting a sensitivity to climate changes.
de Oliveira, K.; de Oliveira, R. R.; Rume, G. d. C.; Rume, T. C.; Fernandes- Brum, C. N.; Kakrana, A.; Mathioni, S.; Meyers, B. C.; Gomes, M. d. S.; Chalfun-Junior, A.
10.1101/2023.07.06.548025 — plant biology — Posted on 2023-07-07
3492 An Enhancer Trap system to track developmental dynamics in Marchantia polymorpha
Marron, A. O.; Sauret-Gueto, S.; Rebmann, M.; Silvestri, L.; Tomaselli, M.; Haseloff, J.
10.1101/2023.07.06.547788 — plant biology — Posted on 2023-07-07
3493 SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis
Vu, K. A. L.; Kumari, K.; Liu, B. H.; Gao, C.; Li, F.; Tang, J.; Maddalo, D.; Auld, D.; Casalena, D.; Tian, X.; Liu, M.; Bassal, M. A.; Moein, S.; Iakovleva, V.; Tan, J.; stein, a.; Zhou, Q.; Fischer, P.; Sigua, L.; Qi, J.; Arthanari, H.; Tenen, D.; Chai, L.
10.1101/2023.07.07.548071 — cancer biology — Posted on 2023-07-07
3494 SoMAS: Finding somatic mutations associated with alternative splicing in human cancers
Tan, H.; Gotea, V.; Seidel, N. E.; Holland, D. O.; Fedkenheuer, K.; Jaiswal, S. K.; Bang-Christensen, S.; Elnitski, L. L.
10.1101/2023.07.06.547933 — cancer biology — Posted on 2023-07-07
3495 The efficacy of CB-103, a first-in-class transcriptional Notch inhibitor, in preclinical models of breast cancer
Vigolo, M.; Urech, C.; Lamy, S.; Monticone, G.; Zabaleta, J.; Hossain, F.; Wyczechowska, D.; Del Valle, L.; O'Regan, R.; Miele, L.; Lehal, R.; Majumder, S.
10.1101/2023.07.06.547830 — cancer biology — Posted on 2023-07-07
3497 Bifunctional small molecules that induce nuclearlocalization and targeted transcriptional regulation
Gibson, W. J.; Sadagopan, A.; Shoba, V. M.; Choudhary, A.; Meyerson, M. L.; Schreiber, S. L.
10.1101/2023.07.07.548101 — biochemistry — Posted on 2023-07-07
3498 Cooperative conformational transitions and the temperature dependence of enzyme catalysis
Walker, E. J.; Hamill, C. J.; Crean, R. M.; Connolly, M. S.; Warrender, A. K.; Kraakman, K. L.; Prentice, E. J.; Steyn-Ross, A.; Steyn-Ross, M.; Pudney, C. R.; van der Kamp, M. W.; Schipper, L. A.; Mulholland, A. J.; Arcus, V. L.
10.1101/2023.07.06.548038 — biochemistry — Posted on 2023-07-07
3500 Massive contractions of Myotonic Dystrophy Type 2-associated CCTG tetranucleotide repeats occur via double strand break repair with distinct requirements for helicases
Papp, D.; Hernandez, L. A.; Mai, T. A.; Haanen, T. J.; O'Donnell, M. A.; Duran, A. T.; Hernandez, S. M.; Narvanto, J. E.; Arguello, B.; Onwukwe, M. O.; Kolar, K.; Mirkin, S. M.; Kim, J. C.
10.1101/2023.07.06.548036 — genetics — Posted on 2023-07-07
3501 Egg hatching success is significantly influenced by the time of thermal stress in multiple hard tick species
Ajayi, O.; Oyen, K.; Davies, B.; Finch, G.; Piller, B. D.; Harmeyer, A. A.; Wendeln, K.; Perretta, C.; Rosendale, A. J.; Benoit, J. B.
10.1101/2022.12.13.518051 — ecology — Posted on 2023-07-07
3504 A role for Vps13-mediated lipid transfer at the ER-endosome contact site in ESCRT-mediated sorting
Suzuki, S.; West, M.; Zhang, Y.; Fan, J. S.; Roberts, R. T.; Odorizzi, G.; Emr, S. D.
10.1101/2023.07.06.547997 — cell biology — Posted on 2023-07-07
3505 Activation of goblet cell stress sensor IRE1β is controlled by the mucin chaperone AGR2
Cloots, E.; Guilbert, P.; Provost, M.; Neidhardt, L.; Van de Velde, E.; Fayazpour, F.; De Sutter, D.; Savvides, S. N.; Eyckerman, S.; Janssens, S.
10.1101/2023.07.06.547951 — cell biology — Posted on 2023-07-07
3507 Non-decameric NLRP3 forms an MTOC-independent inflammasome
Mateo-Tortola, M.; Hochheiser, I. V.; Grga, J.; Mueller, J. S.; Geyer, M.; Weber, A. N. R.; Tapia-Abellan, A.
10.1101/2023.07.07.548075 — molecular biology — Posted on 2023-07-07
3508 CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signalling
Giblin, S. P.; Ranawana, S.; Hassibi, S.; Birchenough, H. L.; Mincham, K. T.; Snelgrove, R. J.; Tsuchiya, T.; Kanegasaki, S.; Dyer, D. P.; Pease, J. E.
10.1101/2023.07.07.548106 — immunology — Posted on 2023-07-07
3509 A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages
Sasaki, I.; Fukuda-Ohta, Y.; Nakai, C.; Wakaki-Nishiyama, N.; Okamoto, C.; Orimo, T.; Okuzaki, D.; Morita, S.; Kaji, S.; Furuta, Y.; Hemmi, H.; Kato, T.; Yamamoto, A.; Tanaka, T.; Hoshino, K.; Fukuda, S.; Miyake, K.; Kuroda, E.; Ishii, K. J.; Iwawaki, T.; Furukawa, K.; Kaisho, T.
10.1101/2023.07.06.547940 — immunology — Posted on 2023-07-07
3510 Cortical neurons obtained from patients-derived GNAO1 iPSCs show altered differentiation and functional properties
Benedetti, M. C.; D'Andrea, T.; Colantoni, A.; Silachev, D.; de Turris, V.; Boussadia, Z.; Babenko, V. A.; Volovikov, E. A.; Belikova, L.; Bogomazova, A. N.; Pepponi, R.; Whye, D.; Buttermore, E. D.; Tartaglia, G. G.; Lagarkova, M. A.; Katanaev, V.; Musayev, I.; Martinelli, S.; Fucile, S.; Rosa, A.
10.1101/2023.06.15.545051 — neuroscience — Posted on 2023-07-07
3511 Multiplexed volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex
Han, X.; Lu, X.; Li, P. H.; Wang, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Adhinarta, J.; Berger, D.; Wu, Y.; Fang, T.; Meral, E. S.; Asraf, S.; Ploegh, H.; Pfister, H.; Wei, D.; Jain, V.; Trimmer, J. S.; Lichtman, J. W.
10.1101/2023.05.20.540091 — neuroscience — Posted on 2023-07-07
3512 A Novel Drosophila Model to Investigates Adipose Tissue Macrophage Infiltration (ATM) and Obesity highlights the Therapeutic Potential of Attenuating Eiger/TNF Signaling to Ameliorate Insulin Resistance and ATM.
Mirzoyan, Z.; Valenza, A. M.; Zola, S.; Bonfanti, C.; Arnaboldi, L.; Ferrari, N.; Pollard, J.; Lupi, V.; Cassinelli, M.; Frattaroli, M.; Sahin, M.; Pasini, M. E.; Bellosta, P.
10.1101/2023.07.06.548016 — physiology — Posted on 2023-07-07
3513 TRIB1 modulates transcriptional programming in breast cancer cells to regulate cell proliferation
McMillan, H. D.; Papachristou, E. K.; Hazlett, J.; Omarjee, S.; Carroll, J.; Black, M.; Mace, P. D.; Dunbier, A.
10.1101/2023.07.06.547928 — cancer biology — Posted on 2023-07-07
3515 PARP1 Inhibition Halts EBV+ Lymphoma Progression by Disrupting the EBNA2/MYC Axis
Napoletani, G.; Soldan, S. S.; Kannan, T.; Preston-Alp, S.; Vogel, P.; Maestri, D.; Caruso, L. B.; Kossenkov, A.; Sobotka, A.; Lieberman, P. M.; Tempera, I.
10.1101/2023.07.05.547847 — cancer biology — Posted on 2023-07-07
3517 Protein Binding Leads to Reduced Stability and Solvated Disorder in the Polystyrene Nanoparticle Corona
Somarathne, R. P.; Amarasekara, D. L.; Kariyawasam, C. S.; Robertson, H. A.; Mayatt, R.; Fitzkee, N. C.
10.1101/2023.07.06.548033 — biophysics — Posted on 2023-07-07
3522 Multimodal hierarchical classification of CITE-seq data delineates immune cell states across lineages and tissues
Caron, D. P.; Specht, W. L.; Chen, D.; Wells, S. B.; Szabo, P. A.; Jensen, I. J.; Farber, D. L.; Sims, P. A.
10.1101/2023.07.06.547944 — genomics — Posted on 2023-07-07
3524 Neural signatures of natural behavior in socializing macaques
Testard, C.; Tremblay, S.; Parodi, F.; DiTullio, R. W.; Acevedo-Ithier, A.; Gardiner, K.; Kording, K. P.; Platt, M.
10.1101/2023.07.05.547833 — neuroscience — Posted on 2023-07-07
3527 Functional Protein Dynamics in a Crystal
Klyshko, E.; Kim, J. S.-H.; McGough, L.; Valeeva, V.; Lee, E.; Ranganathan, R.; Rauscher, S.
10.1101/2023.07.06.548023 — biophysics — Posted on 2023-07-07
3531 Learning Complete Protein Representation by Deep Coupling of Sequence and Structure
Hu, B.; Tan, C.; Xia, J.; Zheng, J.; Huang, Y.; Wu, L.; Liu, Y.; Xu, Y.; Li, S. Z.
10.1101/2023.07.05.547769 — bioinformatics — Posted on 2023-07-07
3532 Mitonuclear sex determination? Empirical evidence frombivalves
Smith, C. H.; Mejia-Trujillo, R.; Breton, S. H.; Pinto, B. J.; Kirkpatrick, M.; Havird, J. C.
10.1101/2023.07.05.547839 — evolutionary biology — Posted on 2023-07-07
3538 The Sterile Insect Technique can efficiently reduce the reproduction of the spotted wing drosophila (Drosophila suzukii) in strawberry
Gard, B.; Panel, A.; Labbetoul, A.; Bosshard, N.; Xuereb, A.; Cariou, B.; Debelle, A.; Oliva, C.; Fellous, S.
10.1101/2023.04.18.537326 — ecology — Posted on 2023-07-07
3539 SARS-CoV-2 Nsp1 regulates translation start site fidelity to promote infection
Aviner, R.; Lidsky, P. V.; Xiao, Y.; Tasseto, M.; Zhang, L.; McAlpine, P. L.; Elias, J.; Frydman, J.; Andino, R.
10.1101/2023.07.05.547902 — microbiology — Posted on 2023-07-07
3540 An ancient ecospecies of Helicobacter pylori found in Indigenous populations and animal adapted lineages.
Tourrette, E.; Torres, R. C.; Svensson, S. L.; Matsumoto, T.; Fauzia, K. A.; Alfaray, R. I.; Vilaichone, R.-K.; Tuan, V. P.; HelicobacterGenomicsConsortium, ; Wang, D.; Olsson, L.; Yadegar, A.; Zhou, Z.; Yamaoka, Y.; Thorell, K.; Falush, D.
10.1101/2023.04.28.538659 — microbiology — Posted on 2023-07-07
3541 GENIUS: GEnome traNsformatIon and spatial representation of mUltiomicS data
Sokac, M.; Kjaer, A.; Dyrskjot Andersen, L.; Haibe-Kains, B.; Aerts, H. J. W. L.; Birkbak, N. J.
10.1101/2023.02.09.525144 — bioinformatics — Posted on 2023-07-07
3544 Multiple Pleistocene refugia for Arctic White Heather (Cassiope tetragona) supported by population genomics analyses of contemporary and Little-Ice-Age samples
Elphinstone, C.; Hernandez, F.; Todesco, M.; Legare, J.-S.; Cheung, W.; Sokoloff, P.; Hofgaard, A.; Christiansen, C. T.; Frei, E. R.; Levesque, E.; Daskalova, G. N.; Thomas, H. J.; Myers-Smith, I.; Harris, J.; Saarela, J. M.; May, J. L.; Obst, J.; Boike, J.; Clark, K.; MacIntosh, K.; Betway, K. R.; Bjorkman, M. P.; Moody, M. L.; Schmidt, N. M.; Molgaard, P.; Bjork, R. G.; Hollister, R. D.; Bull, R. D.; Agger, S.; Maire, V.; Case, L.; Henry, G. H. R.; Rieseberg, L. H.
10.1101/2023.07.05.547859 — genomics — Posted on 2023-07-06
3545 Juvenile niches select between two distinct development trajectories and symbiosis modes in vent shrimps
Methou, P.; Gueganton, M.; Copley, J. T.; Watanabe, H. K.; Pradillon, F.; Cambon-Bonavita, M.-A.; Chen, C.
10.1101/2023.07.02.547428 — evolutionary biology — Posted on 2023-07-07
3546 A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence
Hennart, M.; Crestani, C.; Bridel, S.; Armatys, N.; Bremont, S.; Carmi-Leroy, A.; Landier, A.; Passet, V.; Fonteneau, L.; Vaux, S.; Toubiana, J.; Badell-Ocando, E.; Brisse, S.
10.1101/2023.02.20.529124 — microbiology — Posted on 2023-07-07
3547 Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
Liu, C. S. C.; Mandal, T.; Biswas, P.; Hoque, M. A.; Bandopadhyay, P.; Sinha, B. P.; Sarif, J.; D'Rozario, R.; Sinha, D. K.; Sinha, B.; Ganguly, D.
10.1101/2022.08.16.504114 — immunology — Posted on 2023-07-07
3549 Spatial Localization Ability of Planarians Identified Through the Light Maze Paradigm
Qian, R.; Yan, Y.; Zhang, Y.; Chi, Y.; Chen, Y.; Hao, K.; Xu, Z.; Yang, G.; Shao, Z.; Wang, Y.; Li, X.; Lu, C.; Chen, K.; Pei, Y.; Zhang, W.; Wang, B.; Ying, Z.; Huang, K.
10.1101/2022.11.17.516918 — animal behavior and cognition — Posted on 2023-07-07
3550 Diving Behavior Reveals Humidity Sensing Ability of Water Deprived Planarians
Pei, Y.; Qian, R.; Yan, Y.; Zhang, Y.; Tan, L.; Li, X.; Lu, C.; Chen, Y.; Chi, Y.; Hao, K.; Xu, Z.; Yang, G.; Shao, Z.; Wang, Y.; Huang, K.
10.1101/2022.10.12.511880 — animal behavior and cognition — Posted on 2023-07-07
3552 Phenotypic stasis with genetic divergence
Mallard, F.; Noble, L.; Guzella, T.; Afonso, B.; Baer, C. F.; Teotonio, H.
10.1101/2022.05.28.493856 — evolutionary biology — Posted on 2023-07-07
3555 Ablation of oligodendrogenesis in adult mice alters brain microstructure and activity independently of behavioural deficits
Kaller, M. S.; Lazari, A.; Feng, Y.; van der Toorn, A.; Ruehling, S.; Shimizu, T.; Bannerman, D. M.; Vyazovskiy, V.; Richardson, W. D.; Sampaio-Baptista, C.; Johansen-Berg, H.
10.1101/2023.07.06.547854 — neuroscience — Posted on 2023-07-06
3557 xTrimoPGLM: Unified 100B-Scale Pre-trained Transformer for Deciphering the Language of Protein
Chen, B.; Cheng, X.; Gengyang, L.-a.; Li, S.; Zeng, X.; Wang, B.; Jing, G.; Liu, C.; Zeng, A.; Dong, Y.; Tang, J.; Song, L.
10.1101/2023.07.05.547496 — synthetic biology — Posted on 2023-07-06
3558 Ultra-high throughput mapping of genetic design space
O'Connell, R. W.; Rai, K.; Piepergerdes, T. C.; Wang, Y.; Samra, K. D.; Wilson, J. A.; Lin, S.; Zhang, T. H.; Ramos, E.; Sun, A.; Kille, B.; Curry, K. D.; Rocks, J. W.; Treangen, T. J.; Mehta, P.; Bashor, C. J.
10.1101/2023.03.16.532704 — synthetic biology — Posted on 2023-07-06
3561 Comparative analysis of amphibian genomes: an emerging resource for basic and applied research
Kosch, T. A.; Crawford, A. J.; Mueller, R. L.; Wollenberg Valero, K. C.; Power, M. L.; Rodriguez, A.; O'Connell, L. A.; Young, N. D.; Skerratt, L. F.
10.1101/2023.02.27.530355 — genomics — Posted on 2023-07-06
3564 The respiratory enzyme complex Rnf is vital for metabolic adaptation and virulence in Fusobacterium nucleatum
Britton, T. A.; Wu, C.; Chen, Y.-W.; Franklin, D.; Chen, Y.; Camacho, M. I.; Luong, T. T.; Das, A.; Ton-That, H.
10.1101/2023.06.13.544113 — microbiology — Posted on 2023-07-06
3565 Caught in the Act: targeted mutagenesis of the herpesvirus fusogen central helix captures transition states
Zhou, M.; Vollmer, B.; Machala, E.; Chen, M.; Grünewald, K.; Arvin, A. M.; Chiu, W.; Oliver, S. L.
10.1101/2022.11.23.517751 — microbiology — Posted on 2023-07-06
3566 Mammals achieve common neural coverage of visual scenes using distinct sampling behaviors
Samonds, J. M.; Szinte, M.; Barr, C.; Montagnini, A.; Masson, G. S.; Priebe, N. J.
10.1101/2023.03.20.533210 — neuroscience — Posted on 2023-07-06
3568 Evidence for glutamate excitotoxicity that occurs before the onset of striatal cell loss and motor symptoms in an ovine Huntington's Disease model.
Jiang, A.; You, L.; Handley, R. R.; Hawkins, V.; Reid, S. J.; Jacobsen, J. C.; Patassini, S.; Rudiger, S. R.; McLaughlan, C. J.; Kelly, J. M.; Verma, P. J.; Bawden, C. S.; Gusella, J. F.; MacDonald, M. E.; Waldvogel, H. J.; Faull, R. L. M.; Lehnert, K.; Snell, R. G.
10.1101/2023.06.20.545648 — neuroscience — Posted on 2023-07-06
3572 A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis
Paasch, B. C.; Sohrabi, R.; Kremer, J. M.; Nomura, K.; Martz, J.; Kvitko, B.; Tiedje, J. M.; He, S. Y.
10.1101/2023.03.02.527037 — plant biology — Posted on 2023-07-06
3573 Toxicogenomic analysis of the carcinogenic potential of plastic additives
Vincoff, S.; Schleupner, B.; Santos, J.; Morrison, M.; Zhang, N.; Dunphy-Daly, M. M.; Eward, W. C.; Armstrong, A. J.; Diana, Z.; Somarelli, J.
10.1101/2023.06.30.547246 — pharmacology and toxicology — Posted on 2023-07-06
3574 Intercellular extrachromosomal DNA copy number heterogeneity drives cancer cell state diversity
Stoeber, M. C.; Chamorro Gonzalez, R.; Brueckner, L.; Conrad, T.; Wittstruck, N.; Szymansky, A.; Eggert, A.; Schulte, J. H.; Koche, R. P.; Henssen, A. G.; Schwarz, R. F.; Haase, K.
10.1101/2023.01.21.525014 — cancer biology — Posted on 2023-07-06
3575 Technical insights into fluorescence lifetime microscopy of mechanosensitive Flipper probes
Roffay, C.; Garcia Arcos, J. M.; Chapuis, P.; Lopez-Andarias, J.; Schneider, F.; Colom, A.; Tomba, C.; Di Meglio, I.; Dunsing, V.; Matile, S.; Roux, A.; Mercier, V.
10.1101/2022.09.28.509885 — biophysics — Posted on 2023-07-06
3578 Myeloid cell activation during Zika virus encephalitis predicts recovery of functional cortical connectivity
Agner, S. C.; Brier, L. M.; Hill, J. D.; Liu, E. Y.; Bice, A.; Rahn, R. M.; Culver, J. P.; Klein, R. S.
10.1101/2023.07.06.547991 — biophysics — Posted on 2023-07-06
3579 Helicity of a tardigrade disordered protein promotes desiccation tolerance
Biswas, S.; Gollub, E.; Yu, F.; Ginell, G.; Holehouse, A. S.; Sukenik, S.; Boothby, T. C.
10.1101/2023.07.06.548010 — biochemistry — Posted on 2023-07-06
3580 MicroED structure of the human vasopressin 1B receptor
Shiriaeva, A.; Martynowycz, M. W.; Nicolas, W. J.; Cherezov, V.; Gonen, T.
10.1101/2023.07.05.547888 — biochemistry — Posted on 2023-07-06
3581 Engineered Antigen-Binding Fragments for Enhanced Crystallisation of Antibody:Antigen Complexes
Bruce, H. A.; Singer, A. U.; Filippova, E. V.; Blazer, L. L.; Adams, J. J.; Enderle, L.; Ben-David, M.; Radley, E. H.; Mao, D. Y.; Pau, V.; Orlicky, S.; Sicheri, F.; Kourinov, I.; Atwell, S.; Kossiakoff, A. A.; Sidhu, S. S.
10.1101/2023.07.06.548021 — biochemistry — Posted on 2023-07-06
3582 Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from the Marine Cyanobacterium Moorena producens JHB Discovered via Co-culture with Candida albicans
Ngo, T.-E.; Ecker, A. K.; Guild, A.; Remmel, A.; Boudreau, P. B.; Alexander, K. L.; Naman, C. B.; Glukhov, E.; Avalon, N. E.; Shende, V. V.; Gerwick, L.; Gerwick, W. H.
10.1101/2023.07.06.547815 — biochemistry — Posted on 2023-07-06
3584 Structural and dynamical basis for the interaction of HSP70-EEVD with JDP Sis1
Matos, C. O.; Pinheiro, G. M. S.; Caruso, I. P.; Amorim, G. C.; Almeida, F. C. L.; Ramos, C. H. I.
10.1101/2022.11.26.517237 — molecular biology — Posted on 2023-07-06
3585 Increasing Signal Intensity of Fluorescent Oligo-Labeled Antibodies
McCarthy, M. E.; Latham, D. R.; Haskell, C. V.; Patel, N. D.; Pittman, Z. A.; Sanabria, H.; Birtwistle, M. R.
10.1101/2023.07.06.547965 — molecular biology — Posted on 2023-07-06
3586 The Biogenesis of Bacterial PHB Granules
de Koning, E. A.; Panjalingam, M.; Tran, J.; Eckhart, M. R.; Dahlberg, P. D.; Shapiro, L.
10.1101/2023.07.06.548030 — molecular biology — Posted on 2023-07-06
3590 The CPSF phosphatase module links transcription termination to chromatin silencing
Mateo Bonmati, E.; Fang, X.; Maple, R.; Fiedler, M.; Passmore, L. A.; Dean, C. A.
10.1101/2023.07.06.547976 — molecular biology — Posted on 2023-07-06
3591 Accurate quantification of lysyl oxidase concentration in human tissue
Yao, Y.; Perryman, L.; Zahoor, A.; Hamilton, R.; Stolp, J.; Jarolimek, W.
10.1101/2023.07.06.548012 — molecular biology — Posted on 2023-07-06
3595 Rat hepatitis E virus (HEV) cross-species infection and transmission in pigs
Yadav, K. K.; Boley, P. A.; Lee, C. M.; Khatiwada, S.; Jung, K.; Laocharoensuk, T.; Hofstetter, J.; Wood, R.; Hanson, J.; Kenney, S. P.
10.1101/2023.07.06.547957 — microbiology — Posted on 2023-07-06
3596 Barley cultivars shape the abundance, phenotype, genotype and gene expression of their associated microbiota by differential root exudate secretion
Pacheco-Moreno, A.; Bollmann-Giolai, A.; Chandra, G.; Brett, P.; Davies, J.; Thornton, O.; Poole, P.; Ramachandran, V.; Brown, J.; Nicholson, P.; Ridout, C.; DeVos, S.; Malone, J. G.
10.1101/2023.07.05.547901 — microbiology — Posted on 2023-07-06
3597 Bioinformatic correction of bacterial morphology-based extraction bias and chimeras in microbiome sequencing data
Rauer, L.; De Tomassi, A.; Müller, C. L.; Hülpüsch, C.; Traidl-Hoffmann, C.; Reiger, M.; Neumann, A. U.
10.1101/2023.07.06.547990 — microbiology — Posted on 2023-07-06
3600 Exogenous butyrate inhibits butyrogenic metabolism and alters expression of virulence genes in Clostridioides difficile
Pensinger, D.; Dobrila, H. A.; Stevenson, D. M.; Davis, N. M.; Amador-Noguez, D.; Hryckowian, A. J.
10.1101/2023.07.06.548018 — microbiology — Posted on 2023-07-06
3602 Simultaneous Spectral Differentiation of Multiple Fluorophores in Super-resolution Imaging Using a Glass Phase Plate
Fernando, S. I.; Martineau, J. T.; Hobson, R. J.; Vu, T. N.; Baker, B.; Mueller, B.; Menon, R.; Jorgensen, E. M.; Gerton, J.
10.1101/2022.07.11.499581 — biophysics — Posted on 2023-07-06
3603 Fibertools: fast and accurate DNA-m6A calling using single-molecule long-read sequencing
Jha, A.; Bohaczuk, S. C.; Mao, Y.; Ranchalis, J.; Mallory, B. J.; Min, A. T.; Hamm, M. O.; Swanson, E.; Finkbeiner, C.; Li, T.; Whittington, D.; Noble, W. S.; Stergachis, A. B.; Vollger, M. R.
10.1101/2023.04.20.537673 — bioinformatics — Posted on 2023-07-06
3606 Arpin deficiency increases actomyosin contractility and vascular permeability
Montoya-Garcia, A.; Guerrero-Fonseca, I. M.; Chanez-Paredes, S. D.; Hernandez-Almaraz, K. B.; Leon-Vega, I. I.; Silva-Olivares, A.; Betanzos, A.; Mondragon-Castelan, M.; Mondragon-Flores, R.; Salinas-Lara, C.; Vargas-Robles, H.; Schnoor, M.
10.1101/2023.05.29.542762 — cell biology — Posted on 2023-07-06
3607 EFA6R suppresses ovarian cancer cell migration and invasion
Tamaddon-Jahromi, S.; Murphy, K.; Walker, W.; Kanamarlapudi, V.
10.1101/2022.01.21.477266 — cell biology — Posted on 2023-07-06
3610 pUdOs: concise plasmids for bacterial and mammalian cells
Ourida Manigat, F.; Connell, L. B.; Stewart, B. N.; LePabic, A.-R.; Tessier, C. J. G.; Emlaw, J. R.; Calvert, N. D.; Rossl, A.; Shuhendler, A. J.; daCosta, C. J. B.; Campbell-Valois, F.-X.
10.1101/2023.07.05.547852 — synthetic biology — Posted on 2023-07-06
3611 Spiny but photogenic: amateur sightings complement herbarium specimens to reveal the bioregions of cacti
Calvente, A.; Silva, A. P.; Edler, D.; Carvalho, F. A.; Fantinati, M. R.; Zizka, A.; Antonelli, A.
10.1101/2023.03.15.532806 — plant biology — Posted on 2023-07-06
3617 Self-regulating arousal via pupil-based biofeedback
Meissner, S. N.; Baechinger, M.; Kikkert, S.; Imhof, J.; Missura, S.; Carro Dominguez, M.; Wenderoth, N.
10.1101/2022.08.26.505388 — neuroscience — Posted on 2023-07-06
3619 Single transcript-level metabolic responsive landscape of human liver transcriptome
Jiang, C.; Li, P.; Ma, Y.; Yoneda, N.; Nishiwaki, M.; Ohnishi, Y.; Suemizu, H.; Cao, H.
10.1101/2023.07.06.544842 — systems biology — Posted on 2023-07-06
3621 Microhomology-Mediated Circular DNA Formation from Oligonucleosomal Fragments During Spermatogenesis
Hu, J.; Zhang, Z.; Xiao, S.; Cao, Y.; Chen, Y.; Weng, J.; Jiang, H.; Li, W.; Chen, J.-Y.; Liu, C.
10.1101/2023.02.27.530352 — genomics — Posted on 2023-07-06
3626 Fecal and skin microbiota of two rescued Mediterranean monk seal pups during rehabilitation
Dosi, A.; Meziti, A.; Tounta, E.; Koemtzopoulos, K.; Komnenou, A.; Dendrinos, P.; Kormas, K.
10.1101/2023.07.05.546574 — microbiology — Posted on 2023-07-06
3627 Regulation of potassium homeostasis in Caulobacter crescentus
Quintero-Yanes, A.; Collignon, M.; Leger, L.; Mayard, A.; Hallez, R.
10.1101/2023.07.05.547876 — microbiology — Posted on 2023-07-06
3628 Resilient functioning is associated with altered structural brain network topology in adolescents exposed to childhood adversity.
Gonzalez-Garcia, N.; Buimer, E. E.; Moreno-Lopez, L.; Sallie, S. N.; Vasa, F.; Lim, S.; Romero-Garcia, R.; Scheuplein, M.; Whitaker, K.; Jones, P. B.; Dolan, R.; NSPN consortium, ; Fonagy, P.; Goodyer, I.; Bullmore, E.; van Harmelen, A.-L.
10.1101/2023.05.05.538901 — neuroscience — Posted on 2023-07-06
3630 CONSTANS alters the circadian clock in Arabidopsis thaliana
de los Reyes, P.; Romero-Campero, F. J.; Gao, H.; Serrano-Bueno, G.; Romero, J. M.; Valverde, F.
10.1101/2023.01.19.524697 — plant biology — Posted on 2023-07-06
3631 The killing of human gut commensal E. coli ED1a by tetracycline is associated with severe ribosome dysfunction
Khusainov, I.; Romanov, N.; Goemans, C.; Turonova, B.; Zimmerli, C. E.; Welsch, S.; Langer, J.; Typas, A.; Beck, M.
10.1101/2023.07.06.546847 — biophysics — Posted on 2023-07-06
3633 Defense-related callose synthase PMR4 promotes root hair callose deposition and adaptation to phosphate deficiency in Arabidopsis thaliana
Okada, K.; Yachi, K.; Nguyen, T. A. N.; Kanno, S.; Tateda, C.; Lee, T.-H.; Nguyen, U.; Miyashima, S.; Hiruma, K.; Miwa, K.; Maekawa, T.; Notaguchi, M.; Saijo, Y.
10.1101/2023.07.05.547890 — plant biology — Posted on 2023-07-06
3637 Alterations in grey matter structure linked to frequency-specific cortico-subcortical connectivity in schizophrenia via multimodal data fusion
Duda, M.; Faghiri, A.; Belger, A.; Bustillo, J. R.; Ford, J. M.; Mathalon, D. H.; Mueller, B. A.; Pearlson, G. D.; Potkin, S. G.; Preda, A.; Sui, J.; Van Erp, T. G. M.; Calhoun, V. D.
10.1101/2023.07.05.547840 — neuroscience — Posted on 2023-07-06
3640 The Cellular Underpinnings of the Human Cortical Connectome
Zhang, X.-H.; Anderson, K. M.; Dong, H.-M.; Chopra, S.; Dhamala, E.; Emani, P. S.; Margulies, D.; Holmes, A. J.
10.1101/2023.07.05.547828 — neuroscience — Posted on 2023-07-06
3644 Reconfigurations of cortical manifold structure during reward-based motor learning
Nick, Q.; Gale, D. J.; Areshenkoff, C.; De Brouwer, A. J.; Nashed, J. Y.; Wammes, J.; Flanagan, J. R.; Smallwood, J.; Gallivan, J.
10.1101/2023.07.05.547880 — neuroscience — Posted on 2023-07-06
3645 Dearth of smoking-induced mutations in oncogene-driven non-small-cell lung cancer despite smoking exposure
Huang, C.-Y.; Jiang, N.; Shen, M.; Lai, G.; Tan, A. C.; Jain, A.; Saw, S. P.; Ang, M.-K.; Ng, Q. S.; Lim, D. W.-T.; Kanesvaran, R.; Tan, E.-H.; Tan, W. L.; Ong, B.-H.; Chua, K. L.; Anantham, D.; Takano, A.; Lim, T. K. H.; Tam, W. L.; Sim, N. L.; Sanderup, A. J.; Tan, D. S. W.; Rozen, S. G.
10.1101/2023.07.04.547310 — cancer biology — Posted on 2023-07-06
3646 Selective inhibition of interleukin-2 inducible T cell kinase (ITK) enhances anti-tumor immunity in association with Th1-skewing, cytotoxic T cell activation, and reduced T cell exhaustion
Hsu, L.-Y.; Rosenbaum, J. T.; Verner, E.; Jones, W. B.; Hill, C. M.; Janc, J. W.; Buggy, J. J.; Ding, N.; Reneau, J. C.; Khodadoust, M. S.; Kim, Y. H.; Wilcox, R. A.; Miller, R. A.
10.1101/2023.07.05.547822 — cancer biology — Posted on 2023-07-06
3647 Ultra-high field fMRI of visual mental imagery in typical imagers and aphantasic individuals
Liu, J.; Zhan, M.; Hajhajate, D.; Spagna, A.; Dehaene, S.; Cohen, L.; Bartolomeo, P.
10.1101/2023.06.14.544909 — neuroscience — Posted on 2023-07-06
3648 Evolution of circadian behavioral plasticity through cis-regulatory divergence of a neuropeptide gene
Shahandeh, M. P.; Abuin, L.; Lescuyer De Decker, L.; Cergneux, J.; Koch, R.; Nagoshi, E.; Benton, R.
10.1101/2023.07.05.547553 — evolutionary biology — Posted on 2023-07-06
3650 Gut microbiome-based prediction of autoimmune neuroinflammation
Steimle, A.; Neumann, M.; Grant, E.; Willieme, S.; De Sciscio, A.; Parrish, A.; Ollert, M.; Miyauchi, E.; Soga, T.; Fukuda, S.; Ohno, H.; Desai, M. S.
10.1101/2023.04.14.536901 — microbiology — Posted on 2023-07-06
3651 Augmented Super-Resolution Radial Fluctuations (aSRRF) Pushing the Limits of Structured Illumination Microscopy
Zhang, H.; Wang, J.; Jin, L.; Zhu, Y.; Guo, Y.; Zhang, M.; Zhang, Y.; Wang, Z.; Su, Y.; Wu, Y.; Ji, B.; Toomre, D.; Liu, X.; Xu, Y.
10.1101/2023.07.05.547885 — cell biology — Posted on 2023-07-06
3652 Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness
Hensel, I. V.; Elias, S.; Steinhauer, M.; Stoll, B.; Benfatto, S.; Merkt, W.; Krienke, S.; Lorenz, H.-M.; Haas, J.; Wildeman, B.; Resnik-Docampo, M.
10.1101/2023.07.04.547690 — cell biology — Posted on 2023-07-06
3653 Augmented Super-Resolution Radial Fluctuations (aSRRF) Pushing the Limits of Structured Illumination Microscopy
Zhang, H.; Wang, J.; Jin, L.; Zhu, Y.; Guo, Y.; Zhang, M.; Zhang, Y.; Wang, Z.; Su, Y.; Wu, Y.; Ji, B.; Toomre, D.; Liu, X.; Xu, Y.
10.1101/2023.07.05.547885 — cell biology — Posted on 2023-07-06
3654 Bipartite left-right sided endocrine system: processing of contralateral effects of brain injury
Watanabe, H.; Kobikov, Y.; Nosova, O.; Sarkisyan, D.; Galatenko, V.; Carvalho, L.; Maia, G. H.; Lukoyanov, N.; Lavrov, I.; Hallberg, M.; Schouenborg, J.; Zhang, M.; Bakalkin, G.
10.1101/2023.06.28.546857 — neuroscience — Posted on 2023-07-06
3655 Synaptophysin Chaperones the Assembly of 12 SNAREpins under each Ready-Release Vesicle
Bera, M.; Radhakrishnan, A.; Coleman, J.; Kalyana Sundaram, R. V.; Ramakrishnan, S.; Pincet, F.; Rothman, J. E.
10.1101/2023.07.05.547834 — neuroscience — Posted on 2023-07-06
3657 Zero-shot reconstruction of mutant spatial transcriptomes
Okochi, Y.; Matsui, T.; Sakaguchi, S.; Kondo, T.; Naoki, H.
10.1101/2022.12.16.520397 — bioinformatics — Posted on 2023-07-05
3659 Individual Variability in the Structural Connectivity Architecture of the Human Brain
Huang, W.; Chen, H.; Liu, Z.; Dong, X.; Feng, G.; Liu, G.; Ma, G.; Zhang, Z.; Su, L.; Shu, N.
10.1101/2023.01.11.523683 — neuroscience — Posted on 2023-07-06
3661 pUdOs: concise plasmids for bacterial and mammalian cells
Ourida Manigat, F.; Connell, L. B.; Stewart, B. N.; LePabic, A.-R.; Tessier, C. J. G.; Emlaw, J. R.; Calvert, N. D.; Rossl, A.; Shuhendler, A. J.; daCosta, C. J. B.; Campbell-Valois, F.-X.
10.1101/2023.07.05.547852 — synthetic biology — Posted on 2023-07-05
3663 Label-free imaging of DNA interactions with 2D materials
Suelzle, J.; Yang, W.; Shimoda, Y.; Ronceray, N.; Mayner, E.; Manley, S.; Radenovic, A.
10.1101/2023.07.05.547763 — biophysics — Posted on 2023-07-05
3666 Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Cozzolino, K.; Sanford, L.; Hunter, S.; Molison, K.; Erickson, B.; Jones, T.; Ajit, D.; Galbraith, M. D.; Espinosa, J. M.; Bentley, D. L.; Allen, M. A.; Dowell, R. D. A.; Taatjes, D. J.
10.1101/2023.07.05.547813 — biochemistry — Posted on 2023-07-05
3667 Reverse engineering the anti-MUC1 hybridoma antibody 139H2 by mass spectrometry-based de novo sequencing
Peng, W.; Giesbers, K. C. A. P.; Siborova, M.; Beugelink, J. W.; Pronker, M. F.; Schulte, D.; Hilkens, J.; Janssen, B. J. C.; Strijbis, K.; Snijder, J.
10.1101/2023.07.05.547778 — biochemistry — Posted on 2023-07-05
3668 Recent emergence of cephalosporin resistant Salmonella Typhi carrying IncFIB(K) plasmid encoding blaCTX-M-15 gene in India
Thirumoorthy, T. P.; Jacob, J. J.; V, A.; T, M. P.; M, Y.; Shah, B. S.; Shah, A.; Gaigawale, A.; Patel, P.; Mutreja, A.; John, J.; Kang, G.; Veeraraghavan, B.
10.1101/2023.07.05.547856 — genomics — Posted on 2023-07-05
3669 Allelic bias when performing in-solution enrichment of ancient human DNA
Davidson, R.; Williams, M. P.; Roca-Rada, X.; Kassadjikova, K.; Tobler, R.; Fehren-Schmitz, L.; Llamas, B.
10.1101/2023.07.04.547445 — genomics — Posted on 2023-07-05
3670 Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms
Alfatah, M.; Jolyn, J. L. J.; Zhang, Y.; Naaz, A.; Trishia, C. Y. N.; Yogasundaram, S.; Faidzinn, N. A.; Jovian, J. L.; Eisenhaber, B.; Eisenhaber, F.
10.1101/2023.07.04.547743 — genetics — Posted on 2023-07-05
3671 Its a Trap! Escape from an ancient, ancestral sex chromosome system and implication of Foxl2 as a primary sex determininggene in a lizard (Anguimorpha; Shinisauridae)
Pinto, B. J.; Nielsen, S. V.; Sullivan, K. A.; Behere, A.; Keating, S. E.; van Schingen-Khan, M.; Nguyen, T. Q.; Ziegler, T.; Pramuk, J.; Wilson, M. A.; Gamble, T.
10.1101/2023.07.05.547803 — evolutionary biology — Posted on 2023-07-05
3674 Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia
Petersen, U. S. S.; Dembic, M.; Martinez-Pizarro, A.; Richard, E.; Holm, L. L.; Havelund, J. F.; Doktor, T. K.; Larsen, M. R.; Faergeman, N. J.; Desviat, L. R.; Andresen, B. S.
10.1101/2023.07.05.547835 — molecular biology — Posted on 2023-07-05
3677 Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms
Pal, A. K.; Ghorai, D.; Ge, X.; Sarkar, B.; Sahu, A. K.; Chaudhary, V.; Sanyal, S.; Singh, M.; Ghosh, A.
10.1101/2023.07.05.547667 — microbiology — Posted on 2023-07-05
3679 Single-cell quantitative bioimaging of P. berghei liver stage translation.
McLellan, J. L.; Sausman, W.; Reers, A. B.; Bunnik, E. M.; Hanson, K. K.
10.1101/2023.07.05.547872 — microbiology — Posted on 2023-07-05
3683 Multiple Thymic Cell Fate Decisions Regulated by Gads
Shalah, R.; Hallumi, E.; Klopstock, N.; Marzouk, M.; Yablonski, D.
10.1101/2023.07.05.547801 — immunology — Posted on 2023-07-05
3685 Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
Bhuiyan, S.; Xu, M.; Yang, L.; Semizoglou, E.; Bhatia, P.; Pantaleo, K. I.; Tochitsky, I.; Jain, A.; Erdogan, B.; Blair, S.; Cat, V.; Mwirigi, J. M.; Sankaranarayanan, I.; Tavares-Ferreira, D.; Green, U.; McIlvried, L. A.; Copits, B. A.; Bertels, Z.; Del Rosario, J. S.; Widman, A.; Slivicki, R. A.; Yi, J.; Woolf, C. J.; Lennerz, J. K.; Whited, J.; Price, T. J.; Gereau, R.; Renthal, W.
10.1101/2023.07.04.547740 — neuroscience — Posted on 2023-07-05
3689 Automated Purification of DNA Origami with SPRI Beads
Chau, C.; Mohanan, G.; Macaulay, I. C.; Actis, P.; Walti, C.
10.1101/2023.07.05.544573 — biophysics — Posted on 2023-07-05
3690 Self-replication of Abeta42 aggregates occurs on small and isolated fibril sites
Curk, S.; Krausser, J.; Meisl, G.; Frenkel, D.; Linse, S.; Michaels, T. C. T.; Knowles, T. P. J.; Saric, A.
10.1101/2023.07.05.547777 — biophysics — Posted on 2023-07-05
3691 Dynamic landscape of the intracellular termini of ASIC1a
Cullinan, M. M.; Klipp, R. C.; Camenisch, A.; Bankston, J. R.
10.1101/2023.07.05.547693 — biophysics — Posted on 2023-07-05
3692 ABDS: tool suite for analyzing biologically diverse samples
Du, D.; Bhardwaj, S.; Parker, S. J.; Cheng, Z.; Zhang, Z.; Lu, Y.; Van Eyk, J. E.; Yu, G.; Clarke, R.; Herrington, D. M.; Wang, Y.
10.1101/2023.07.05.547797 — bioinformatics — Posted on 2023-07-05
3696 DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images
Papereux, S.; Leconte, L.; Valades-Cruz, C. A.; Liu, T.; Dumont, J.; Chen, Z.; Salamero, J.; Kervrann, C.; Badoual, A.
10.1101/2023.07.05.547594 — bioinformatics — Posted on 2023-07-05
3698 Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors
Maharana, J.; Sano, F. K.; Sarma, P.; Yadav, M. K.; Duan, L.; Stepniewski, T. M.; Chaturvedi, M.; Ranjan, A.; Singh, V.; Saha, S.; Mahajan, G.; Chami, M.; Shihoya, W.; Selent, J.; Chung, K. Y.; Banerjee, R.; Nureki, O.; Shukla, A. K.
10.1101/2023.07.05.547776 — biochemistry — Posted on 2023-07-05
3700 Evolution of circadian behavioral plasticity through cis-regulatory divergence of a neuropeptide gene
Shahandeh, M. P.; Abuin, L.; Lescuyer De Decker, L.; Cergneux, J.; Koch, R.; Nagoshi, E.; Benton, R.
10.1101/2023.07.05.547553 — evolutionary biology — Posted on 2023-07-05
3702 Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.
Yenilmez, B.; Harney, S. M.; DiMarzio, C.; Kelly, M.; Min, K.; Echeverria, D.; Bramato, B. M.; Jackson, S. O.; Reddig, K.; Kim, J. K.; Khvorova, A.; Czech, M. P.
10.1101/2023.07.05.547848 — molecular biology — Posted on 2023-07-05
3704 Yeast-based heterologous production of the Colletochlorin family of fungal secondary metabolites
Geistodt-Kiener, A.; Totozafy, J. C.; Le Goff, G.; Vergne, J.; Sakai, K.; Ouazzani, J.; Mouille, G.; Viaud, M.; O'Connell, R. J.; Dallery, J.-F.
10.1101/2023.07.05.547564 — microbiology — Posted on 2023-07-05
3706 Effects of sexual dimorphism and estrous cycle on C. difficile infections in rodent models
Phan, J. R.; Washington, M.; Do, D. M.; Mata, T. V.; Niamba, M.; Heredia, E.; Soriano, R.; Hassan, C.; Cross, C. L.; Abel-Santos, E.
10.1101/2023.07.05.547871 — microbiology — Posted on 2023-07-05
3707 Novel co-culture strategies of tumor organoids with autologous T-cells reveal clinically relevant combinations of immune-checkpoint and targeted therapies
Podaza, E.; Capuano, J.; Al Assaad, M.; Kuo, H.-h.; Markowitz, G.; Irizarry, A.; Ravichandran, H.; Ackermann, S.; Kane, T.; Manohar, J.; Sigouros, M.; Moyer, J.; Bhinder, B.; Chandra, P.; Malbari, M.; Boehnke, K.; Mosquera, J. M.; Mittal, V.; Sboner, A.; Gokozan, H.; Altorki, N.; Elemento, O.; Martin, M. L.
10.1101/2023.07.05.546622 — immunology — Posted on 2023-07-05
3708 Continuous Evaluation of Denoising Strategies in Resting-State fMRI Connectivity Using fMRIPrep and Nilearn
Wang, H.-T.; Meisler, S. L.; Sharmarke, H.; Clarke, N.; Gensollen, N.; Markiewicz, C. J.; Paugam, F.; Thirion, B.; Bellec, P.
10.1101/2023.04.18.537240 — neuroscience — Posted on 2023-07-05
3712 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E.; Baker, T.; Lesluyes, T.; Monlong, J.; Abe, K. T.; Coelho, P. P.; Schwartz, M.; Zou, D.; Morin, G.; Pacis, A.; Yang, Y.; Martinez, C.; Barber, J.; Kuasne, H.; Li, R.; Bourgey, M.; Fortier, A.-M.; Davison, P. G.; Omeroglu, A.; Guiot, M. C.; Morris, Q.; Kleinman, C. L.; Huang, S.; Gingras, A.-C.; Ragoussis, I.; Bourque, G.; Van Loo, P.; Park, M.
10.1101/2023.06.10.544434 — genomics — Posted on 2023-07-05
3714 Mutational meltdown in asexual populations doomed to extinction
Olofsson, P.; Chipkin, L.; Daileda, R. C.; Azevedo, R. B. R.
10.1101/448563 — evolutionary biology — Posted on 2023-07-05
3716 Bam complex associated proteins in Escherichia coli are functionally linked to peptidoglycan biosynthesis, membrane fluidity and DNA replication
Bryant, J. A.; Staunton, K. A.; Doherty, H. M.; Alao, M. B.; Ma, X.; Morcinek-Orlowska, J.; Goodall, E. C. A.; Gray, J.; Milner, M.; Cole, J. A.; de Cogan, F.; Knowles, T. J.; Glinkowska, M. K.; Moradigaravand, D.; Henderson, I. R.; Banzhaf, M.
10.1101/2023.07.05.547807 — microbiology — Posted on 2023-07-05
3718 Identification of State Markers in Anorexia Nervosa: Replication and Extension of Inflammation Associated Biomarkers Using Multiplex Profiling in Anorexia Nervosa and Atypical Anorexia Nervosa
Breithaupt, L.; Holsen, L. M.; Ji, C.; Hu, J.; Petterway, F.; Rosa-Caldwell, M.; Nilsson, I. A. K.; Thomas, J. J.; Williams, K. A.; Boutin, R.; Bulik, C.; Arnold, S. E.; Lawson, E. A.; Misra, M.; Eddy, K. T.
10.1101/2023.06.30.547289 — immunology — Posted on 2023-07-05
3719 Sex and APOE Genotype Influence Respiratory Function Under Hypoxic and Hypoxic-Hypercapnic Conditions
Taylor, C. E.; Mendenhall, L. E.; Sunshine, M. D.; Wilson, J. N.; Calulot, C. M.; Sun, R. C.; Johnson, L. A.; Alilain, W. J.
10.1101/2022.08.03.502692 — neuroscience — Posted on 2023-07-05
3722 Hip thrust and back squat training elicit similar gluteus muscle hypertrophy and transfer similarly to the deadlift
Plotkin, D. L.; Rodas, M. A.; Vigotsky, A.; McIntosh, M. C.; Breeze, E.; Ubrik, R.; Robitzsch, C.; Agyin-Birikorang, A.; Mattingly, M. L.; Michel, J. M.; Kontos, N. J.; Fruge, A. D.; Wilburn, C. M.; Weimar, W. H.; Bashir, A.; Beyers, R. J.; Henselmans, M.; Contreras, B. M.; Roberts, M. D.
10.1101/2023.06.21.545949 — physiology — Posted on 2023-07-05
3723 Impact of combinatorial histone modifications on acetyllysine recognition by the ATAD2 and ATAD2B bromodomains
Phillips, M.; Malone, K. L.; Boyle, B. W.; Montgomery, C.; Kressy, I. A.; Joseph, F. M.; Bright, K. M.; Boyson, S. P.; Chang, S.; Nix, J. C.; Young, N. L.; Jeffers, V.; Frietze, S. E.; Glass, K. C.
10.1101/2022.11.14.516501 — biochemistry — Posted on 2023-07-05
3724 Malaria resistance-related biological adaptation and complex evolutionary footprints of Tai-Kadai people inferred from 796 genomes
Duan, S.; Wang, M.; Wang, Z.; Liu, Y.; Jiang, X.; Su, H.; Cai, Y.; Sun, Q.; Sun, Y.; Li, X.; Chen, J.; Zhang, Y.; Yan, J.; Nie, S.; Hu, L.; Tang, R.; Yun, L.; Wang, C.; Liu, C.; Yang, J.; He, G. G.
10.1101/2023.07.04.547671 — genetics — Posted on 2023-07-05
3725 Mapping gut bacteria into functional niches reveals the ecological structure of human gut microbiomes
Anthamatten, L.; Rogalla von Bieberstein, P.; Thabuis, C.; Menzi, C.; Reichlin, M.; Meola, M.; Rodriguez, B.; Cordero, O. X.; Lacroix, C.; de Wouters, T.; Leventhal, G. E.
10.1101/2023.07.04.547750 — microbiology — Posted on 2023-07-05
3726 A familial missense variant in the AD gene SORL1 impairs its maturation and endosomal sorting.
Fazeli, E.; Child, D. D.; Bucks, S. A.; Stovarsky, M.; Edwards, G.; Yu, C.-E.; Latimer, C.; Kitago, Y.; Bird, T.; Andersen, O.; Jayadev, S.; Young, J. E.
10.1101/2023.07.01.547348 — neuroscience — Posted on 2023-07-05
3728 A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training
Roberts, M.; Ruple, B.; Godwin, J.; McIntosh, M.; Chen, S.-Y.; Kontos, N.; Agyin-Birikorang, A.; Michel, J. M.; Plotkin, D.; Mattingly, M.; Mobley, C. B.; Ziegenfuss, T.; Fruge, A.; Kavazis, A.
10.1101/2023.06.02.543459 — physiology — Posted on 2023-07-05
3729 ent-Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice
Gochman, A.; Do, T. Q.; Kim, K.; Schwarz, J. A.; Thorpe, M. P.; Blackwell, D. J.; Smith, A. N.; Akers, W. S.; Cornea, R. L.; Laver, D. L.; Johnston, J. N.; Knollmann, B. C.
10.1101/2023.07.03.547578 — pharmacology and toxicology — Posted on 2023-07-05
3730 An indocyanine green-based liquid biopsy test for circulating tumor cells for pediatric liver cancer
Espinoza, A. F.; Kureti, P.; Patel, R. H.; Govindu, S. R.; Armbruster, B. W.; Urbicain, M.; Patel, K. R.; Lopez-Terrada, D.; Vasudevan, S. A.; Woodfield, S. E.
10.1101/2023.07.03.547557 — cancer biology — Posted on 2023-07-05
3731 CREID- A ChemoReceptor-Effector Interaction Database
Peta, V. J.; Hartman, T.; Aryal, S.; Gurung, B. S.; Singh, R.; Haas, S.; Bomgni, A.; Do, T.; Dhiman, S. S.; Gadhamshetty, V.; Gnimpieba, E.
10.1101/2023.05.04.539426 — bioengineering — Posted on 2023-07-05
3734 Separating the control of moving and holding still in post-stroke arm paresis
Hadjiosif, A. M.; Kita, K.; Albert, S. T.; Scheidt, R. A.; Shadmehr, R.; Krakauer, J. W.
10.1101/2022.11.26.517884 — neuroscience — Posted on 2023-07-05
3735 Functional variations in gamma-secretase activity are critical determinants of the clinical, biomarker, and cognitive progression of autosomal dominant Alzheimer's disease
Schultz, S.; Liu, L.; Schultz, A.; Fitzpatrick, C.; Levin, R.; Bellier, J.-P.; Shirzadi, Z.; Mathurin, N.; Chen, C.; Benzinger, T.; Day, G.; Farlow, M.; Gordon, B.; Hassenstab, J.; Jack, C.; Jucker, M.; Karch, C.; Lee, J.; Levin, J.; Perrin, R.; Schofield, P.; Xiong, C.; Johnson, K.; McDade, E.; Bateman, R.; Sperling, R.; Selkoe, D.; Chhatwal, J.; the Dominantly Inherited Alzheimer's Network Investigators,
10.1101/2023.07.04.547688 — neuroscience — Posted on 2023-07-05
3737 Robust prediction of patient outcomes with immune checkpoint blockade therapy for cancer using common clinical, pathologic, and genomic features
Chang, T.-G.; Cao, Y.; Sfreddo, H.; Dhruba, S. R.; Lee, S.-H.; Valero, C.; Yoo, S.-K.; Chowell, D.; Morris, L. G. T.; Ruppin, E.
10.1101/2023.07.04.547697 — cancer biology — Posted on 2023-07-05
3738 Small extracellular vesicles promote stiffness-mediated metastasis
Sneider, A.; Liu, Y.; Starich, B.; Du, W.; Marar, C.; Faqih, N.; Ciotti, G. E.; Kim, J. H.; Krishnan, S.; Ibrahim, S.; Igboko, M.; Locke, A.; Lewis, D. M.; Hong, H.; Karl, M.; Vij, R.; Russo, G. C.; Nair, P. R.; Gomez-de-Mariscal, E.; Habibi, M.; Munoz-Barrutia, A.; Gu, L.; Eisinger-Mathason, T. S. K.; Wirtz, D.
10.1101/2023.07.01.545937 — cancer biology — Posted on 2023-07-05
3743 Exogenous corticosterone administration during pregnancy alters placental and fetal thyroid hormone availability in females.
Paul, E. N.; Shubitidze, S.; Rahim, R.; Rucker, I.; Valin, L.; Apostle, S.; Pospisilik, J. A.; Racicot, K. E.; Smith, A. L.
10.1101/2023.07.05.547278 — developmental biology — Posted on 2023-07-05
3744 Cortical Adaptation Mechanism in the Delta Band of Post-Stroke Aphasic subjects during Naming Task
Renaud-D'Ambra, M.; Aksenov, A.; Mesnildrey, Q.; Hartwigsen, G.; Volpert, V.; Beuter, A.
10.1101/2023.07.04.544349 — neuroscience — Posted on 2023-07-05
3745 Primordial germ cell DNA demethylation and development require DNA translesion synthesis.
Shah, P.; Hill, R. J.; Clark, S.; Dion, C.; Abakir, A.; Arends, M.; Leitch, H.; Reik, W.; Crossan, G.
10.1101/2023.07.05.547775 — developmental biology — Posted on 2023-07-05
3746 Metabolism regulates muscle stem cell self-renewal by connecting the microenvironment and histone acetylation
Ly, C. H.; Chung, J. D.; Nguyen, J. H.; Tian, L.; Schroeder, J.; Knaupp, A. S.; Su, S.; Trieu, J.; Salmi, T. M.; Zalcenstein, D.; Jabbari, J. S.; Boughton, B. A.; Cox, A. G.; Naik, S. H.; Polo, J. M.; Ritchie, M. E.; Lynch, G. S.; Ryall, J. G.
10.1101/2023.07.04.547746 — cell biology — Posted on 2023-07-05
3747 Control of C. elegans growth arrest by stochastic, yet synchronized DAF-16/FOXO nuclear translocation pulses
Demirbas, B.; Filina, O.; Louisse, T.; Goos, Y.; Sanchez-Romero, M. A.; Olmedo, M.; van Zon, J.
10.1101/2023.07.05.547674 — cell biology — Posted on 2023-07-05
3750 Brain-wide representations of prior information in mouse decision-making
Findling, C.; Hubert, F.; International Brain Laboratory, ; Acerbi, L.; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Latham, P. E.; Lau, P. Y. P.; Mainen, Z.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Pan-Vazquez, A.; Paninski, L.; Pillow, J.; Rossant, C.; Roth, N.; Schaeffer,
10.1101/2023.07.04.547684 — neuroscience — Posted on 2023-07-05
3751 Evolutionary Trajectory of Pattern Recognition Receptors in Plants
Ngou, B. P. M.; Wyler, M.; Schmid, M. W.; Kadota, Y.; Shirasu, K.
10.1101/2023.07.04.547604 — plant biology — Posted on 2023-07-05
3752 An ANI gap within bacterial species that advances the definitions of intra-species units
Rodriguez-R, L. M.; Conrad, R. E.; Viver, T.; Feistel, D. J.; Lindner, B. G.; Venter, S. N.; Orellana, L. H.; Amann, R.; Rossello-Mora, R.; Konstantinidis, K. T.
10.1101/2022.06.27.497766 — microbiology — Posted on 2023-07-05
3753 Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
Bhuiyan, S.; Xu, M.; Yang, L.; Semizoglou, E.; Bhatia, P.; Pantaleo, K. I.; Tochitsky, I.; Jain, A. A.; Erdogan, B.; Blair, S.; Cat, V.; Mwirigi, J. M.; Sankaranarayanan, I.; Tavares-Ferreira, D.; Green, U.; McIlvried, L. A.; Copits, B. A.; Bertels, Z.; Del Rosario, J. S.; Widman, A.; Slivicki, R. A.; Yi, J.; Woolf, C. J.; Lennerz, J. K.; Whited, J.; Price, T. J.; Gereau, R.; Renthal, W.
10.1101/2023.07.04.547740 — neuroscience — Posted on 2023-07-05
3754 Deletion of VPS50 protein in mice brain impairs synaptic function and behavior
Ahumada-Marchant, C.; Ancaten-Gonzalez, C.; Haensgen, H.; Brauer, B.; Arancibia, F.; Droste, R.; Horvitz, H. R.; Constantine-Paton, M.; Arriagada, G.; Chavez, A.; Bustos, F. J.
10.1101/2023.07.04.547745 — neuroscience — Posted on 2023-07-05
3756 Comparative Analysis of Whole Transcriptome Single-Cell Sequencing Technologies in Complex Tissues
Salcher, S.; Heidegger, I.; Untergasser, G.; Fotakis, G.; Scheiber, A.; Martowicz, A.; Noureen, A.; Krogsdam, A.; Schatz, C.; Schafer, G.; Trajanoski, Z.; Wolf, D.; Sopper, S.; Pircher, A.
10.1101/2023.07.03.547464 — cancer biology — Posted on 2023-07-05
3758 A flexible implant towards acute intrapancreatic electrophysiology
Pascual, D.; Brauns, L.; Domes, R.; Tisler, M. K.; Koegel, M.; Stumpf, A.; Kirschniak, A.; Rolinger, J.; Kraushaar, U.; Jones, P. D.
10.1101/2023.03.17.532901 — bioengineering — Posted on 2023-07-05
3759 SH2 domain protein E (SHE) and ABL signaling regulate blood vessel size
Schumacher, J. A.; Wright, Z. A.; Rufin Florat, D.; Anand, S. K.; Dasyani, M.; Klimkaite, L.; Bredemeier, N. O.; Gurung, S.; Koller, G. M.; Aguera, K. N.; Chadwick, G. P.; Johnson, R. D.; Davis, G. E.; Sumanas, S.
10.1101/2023.07.03.547455 — developmental biology — Posted on 2023-07-05
3760 Discovering host protein interactions specific for SARS-CoV-2 RNA genome
Giambruno, R.; Zacco, E.; Ugolini, C.; Vandelli, A.; Mulroney, L.; D'Onghia, M.; Giuliani, B.; Criscuolo, E.; Castelli, M.; Clementi, N.; Clementi, M.; Mancini, N.; Bonaldi, T.; Gustincich, S.; Leonardi, T.; Tartaglia, G. G.; Nicassio, F.
10.1101/2022.07.18.499583 — molecular biology — Posted on 2023-07-05
3761 Alternative cell entry mechanisms for SARS-CoV-2 and multiple animal viruses
Ojha, R.; Jiang, A.; Mantyla, E.; Modhiran, N.; Witte, R.; Gaudin, A.; De Zanetti, L.; Gormal, R.; Vihinen-Ranta, M.; Mercer, J.; Suomalainen, M.; Greber, U. F.; Yamauchi, Y.; Yves-Lozach, P.; Helenius, A.; Vapalahti, O.; Young, P.; Watterson, D.; Meunier, F. A.; Joensuu, M.; Balistreri, G.
10.1101/2023.07.02.547368 — microbiology — Posted on 2023-07-05
3762 Immune-Epithelial Dynamics and Tissue Remodeling in Chronically Inflamed Nasal Epithelium via Multi-scaled Transcriptomics
Liao, G.; Nakayama, T.; Lee, I. T.; Zhu, B.; Overdevest, J. B.; Yan, C. H.; Zarabanda, D.; Gall, P. A.; Dholakia, S. S.; Borchard, N. A.; Yang, A.; Kim, D.; Bravo, D. T.; Patel, Z. M.; Hwang, P. H.; Wagh, D.; Coller, J.; Philips, K.; Chang, M. T.; Lechner, M.; Ma, Q.; Li, Z.; Nolan, G.; Barouch, D.; Nayak, J. V.; Jiang, S.
10.1101/2023.07.01.547352 — immunology — Posted on 2023-07-05
3763 Brain-wide representations of prior information in mouse decision-making
Findling, C.; Hubert, F.; International Brain Laboratory, ; Acerbi, L.; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Latham, P. E.; Lau, P. Y. P.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Paninski, L.; Pan-Vazquez, A.; Pillow, J.; Rossant, C.; Roth, N.; Schaeffer, R.; Schartn
10.1101/2023.07.04.547684 — neuroscience — Posted on 2023-07-05
3764 The neural basis of defensive behaviour evolution in Peromyscus mice
Baier, F.; Reinhard, K.; Tong, V.; Murman, J.; Farrow, K.; Hoekstra, H.
10.1101/2023.07.04.547734 — neuroscience — Posted on 2023-07-05
3765 Consequence assessment and behavioral patterns of inhibition in decision-making: modelling its underlying mechanisms
Cecchini, G.; DePass, M.; Baspinar, E.; Andujar, M.; Ramawat, S.; Pani, P.; Ferraina, S.; Destexhe, A.; Moreno-Bote, R.; Cos, I.
10.1101/2023.02.14.528595 — neuroscience — Posted on 2023-07-05
3766 Chromatin attachment to the nuclear matrix represses hypocotyl elongation in Arabidopsis thaliana
Xu, L.; Zheng, S.; Witzel, K.; Slijke, E. V. D.; Baekelandt, A.; Mylle, E.; Van Damme, D.; JCheng, J.; Jaeger, G. D.; Inze, D.; JIANG, H.
10.1101/2023.07.05.547753 — plant biology — Posted on 2023-07-05
3767 Glycoprotein VI is Critical for the Detection and Progression of Abdominal Aortic Aneurysms
Benson, T. W.; Pike, M. M.; Spuzzillo, A.; Hicks, S. M.; Pham, M.; Mix, D. S.; Brunner, S. I.; Wadding-Lee, C. A.; Conrad, K. A.; Russell, H. M.; Jennings, C.; Coughlin, T. M.; Aggarwal, A.; Lyden, S.; Mani, K.; Bjorck, M.; Wanhainen, A.; Bhandari, R.; Lipworth, L.; Robinson-Cohen, C.; Caputo, F. J.; Shim, S.; Edwards, T. L.; Tranter, M.; Gardiner, E. E.; Mackman, N.; Cameron, S. J.; Owens, A. P.
10.1101/2023.07.02.547361 — pathology — Posted on 2023-07-05
3768 HIV-1 Vpu protein forms stable oligomers in aqueous solution via its transmembrane domain self-association
Majeed, S.; Dang, L.; Islam, M. M.; Ishola, O.; Borbat, P. P.; Ludtke, S. J.; Georgieva, E. R.
10.1101/2023.05.08.539839 — biophysics — Posted on 2023-07-05
3769 MIDAS: a deep generative model for mosaic integration and knowledge transfer of single-cell multimodal data
He, Z.; Chen, Y.; Hu, S.; An, S.; Shi, J.; Liu, R.; Zhou, J.; Dong, G.; Shi, J.; Zhao, J.; Wang, J.; Zhu, Y.; Ou-Yang, L.; Bo, X.; Ying, X.
10.1101/2022.12.13.520262 — bioinformatics — Posted on 2023-07-05
3771 FeS-cluster coordination of vertebrate thioredoxins regulates suppression of hypoxia-induced factor 2α through iron regulatory protein 1
Berndt, C.; Hanschmann, E.-M.; Jordt, L. M.; Gellert, M.; Thewes, L.; Ortegon Salas, C.; Poschmann, G.; Mueller, C. S.; Bodnar, Y.; Schippers, S.; Handorf, O.; Nowack, R.; Moulis, J.-M.; Schulzke, C.; Schuenemann, V.; Lillig, C. H.
10.1101/2020.08.04.235721 — biochemistry — Posted on 2023-07-05
3773 Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness
Hensel, I. V.; Elias, S.; Steinhauer, M.; Stoll, B.; Benfatto, S.; Merkt, W.; Krienke, S.; Lorenz, H.-M.; Haas, J.; Wildeman, B.; Resnik-Docampo, M.
10.1101/2023.07.04.547690 — cell biology — Posted on 2023-07-05
3780 Heather pollen is not necessarily a healthy diet for bumble bees
Tourbez, C.; Semay, I.; Michel, A.; Michez, D.; Gerbaux, P.; Gekiere, A.; Vanderplanck, M.
10.1101/2023.04.06.535809 — ecology — Posted on 2023-07-05
3781 Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling.
Petersen, E. N.; Pavel, M. A.; Hansen, S. S.; Gudheti, M.; Wang, H.; Yuan, Z.; Murphy, K. R.; Ja, W. W.; Ferris, H. A.; Jorgensen, E. M.; Hansen, S. B.
10.1101/758896 — neuroscience — Posted on 2023-07-05
3783 A new concept in antiviral drug design yields a potent influenza inhibitor
Mackenzie-Kludas, C.; Wu, W.-Y.; Jin, B.; McKimm-Breschkin, J. L.; Seah, E. L.; Jones, P.; Fairmaid, E.; Tai, C. M. K.; Oh, D. Y.; Jenkins, P.; Hurt, A. C.; Brown, L. E.
10.1101/2022.11.08.515737 — microbiology — Posted on 2023-07-04
3790 Vaccination with Helicobacter pylori attachment proteins protects against gastric cancer
Boren, T.; Bugaytsova, J. A.; Piddubnyi, A.; Tkachenko, I.; Rakhimova, L.; Olofsson Edlund, J.; Thorell, K.; Marcotte, H.; Lundquist, A.; Schon, K.; Suerbaum, S.; Schulz, C.; Malfertheiner, P.; Hansen, L. M.; Solnick, J. V.; Moskalenko, R.; Hammarstrom, L.
10.1101/2023.05.25.542131 — immunology — Posted on 2023-07-04
3792 A neural mechanism for discriminating threatening from safe social experiences
Kassraian, P.; Bigler, S.; Gilly, D. M.; Shrotri, N.; Siegelbaum, S. A.
10.1101/2023.07.04.547723 — neuroscience — Posted on 2023-07-04
3793 Alzheimer's disease associated isoforms of human CD33 distinctively modulate microglial cell responses in 5XFAD mice
Eskandari-Sedighi, G.; Crichton, M.; Zia, S.; Gomez, E.; St. Laurent, C. D.; Cortez, L. M.; Patel, Z. H.; Sidhu, G.; Sarkar, S.; Aghanya, V.; Sim, V. L.; Tan, Q.; Julien, O.; Plemel, J. R.; Macauley, M. S.
10.1101/2023.07.04.547548 — neuroscience — Posted on 2023-07-04
3797 Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects
Plavskin, Y.; de Biase, M. S.; Ziv, N.; Janska, L.; Zhu, Y. O.; Hall, D. W.; Schwarz, R. F.; Tranchina, D.; Siegal, M. L.
10.1101/2023.07.04.547687 — evolutionary biology — Posted on 2023-07-04
3801 Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease.
Holcomb, L.; Holman, J. M.; Hurd, M.; Lavoie, B.; Colucci, L.; Hunt, B.; Hunt, T.; Kinney, M.; Pathak, J.; Mawe, G. M.; Moses, P. L.; Perry, E.; Stratigakis, A.; Zhang, T.; Chen, G.; Ishaq, S. L.; Li, Y.
10.1101/2023.01.27.525953 — microbiology — Posted on 2023-07-04
3802 Neuron-dependent tuft cell expansion initiates sinonasal allergic Type 2 inflammation
Ortiz-Carpena, J. F.; Inclan-Rico, J. M.; Weiner, M. B.; Pastore, C. F.; Hung, L.-Y.; Wilkerson, W. B.; Lin, C.; Gentile, M. E.; Cohen, N. A.; Abdus-Saboor, I.; Vaughan, A. E.; Rossi, H. L.; Herbert, D. R.
10.1101/2023.07.04.547596 — immunology — Posted on 2023-07-04
3808 A Brain-Wide Map of Neural Activity during Complex Behaviour
International Brain Lab, ; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; Dayan, P.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Findling, C.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Hubert, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Lau, P. Y. P.; Mainen, Z. F.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Pan-Vazquez, A.; Pouget, A.; Rossant, C.; Roth, N.; Schaeffer, R.; Schartner, M.; Shi, Y.; Socha
10.1101/2023.07.04.547681 — neuroscience — Posted on 2023-07-04
3811 Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper
Jiang, Y.; Zhang, X.-Y.; Li, S.; Xie, Y.-C.; Li, Z.; Jin, D.; Yang, Y.; Pu, Z.; Zhang, L.; Lu, J.-B.; Huang, H.-J.; Zhang, C.-X.; He, S. Y.
10.1101/2023.05.24.542203 — plant biology — Posted on 2023-07-04
3812 Roles of microbiota in autoimmunity in Arabidopsis
Cheng, Y. T.; Thireault, C. A.; Paasch, B. C.; Zhang, L.; He, S. Y.
10.1101/2023.03.06.531303 — plant biology — Posted on 2023-07-04
3813 Cryo-EM structure of TMEM63C suggests it functions as a monomer
Qin, Y.; Yu, D.; Wu, D.; Dong, J.; Li, W. T.; Ye, C.; Cheung, K. C.; Zhang, Y.; Xu, Y.; Wang, Y.; Shi, Y. S.; Dang, S.
10.1101/2023.07.04.547736 — biophysics — Posted on 2023-07-04
3820 Functional and regulatory diversification of circadian rhythm period genes during the evolution of vertebrates
KWAK, J. S.; Leon-Tapia, M. A.; Diblasi, C.; Manousi, D.; Gronvold, L.; Sandvik, G. K.; Saitou, M.
10.1101/2023.03.09.531707 — evolutionary biology — Posted on 2023-07-04
3821 Photosynthetic and water transport strategies of plants along a tropical forest aridity gradient: a test of optimality theory
Zhang-Zheng, H.; Malhi, Y.; Gvozdevaite, A.; Peprah, T.; Boackye, M.; Zieminska, K.; Adu-Bredu, S.; Aguirre-Gutierrez, J.; Sandoval, D.; Prentice, C.; Oliveras, I.
10.1101/2023.01.10.523419 — ecology — Posted on 2023-07-04
3822 Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations
Klem, J. R.; Schwantes-An, T.-H.; Abreu, M.; Suttie, M.; Gray, R.; Vo, H.; Conley, G.; Foroud, T. M.; Wetherill, L.; CIFASD, ; Lovely, C. B.
10.1101/2023.06.28.546932 — developmental biology — Posted on 2023-07-04
3823 Covalent macrocyclic proteasome inhibitors mitigate resistance in Plasmodium falciparum
Bennett, J. M.; Ward, K. E.; Muir, R.; Kabeche, S.; Yoo, E.; Yeo, T.; Lam, G.; Zhang, H.; Almaliti, J.; Berger, G.; Faucher, F. F.; Lin, G.; Gerwick, W. H.; Yeh, E.; Fidock, D. A.; Bogyo, M.
10.1101/2023.07.03.547579 — microbiology — Posted on 2023-07-04
3830 Basal MET Phosphorylation is an Indicator of Hepatocyte Dysregulation in Liver Disease
Burbano de Lara, S.; Kemmer, S.; Biermayer, I.; Feiler, S.; Vlasov, A.; D'Alessandro, L. A.; Helm, B.; Dieter, Y.; Ghallab, A.; Hengstler, J. G.; Hoffmann, K.; Schilling, M.; Timmer, J.; Klingmueller, U.
10.1101/2023.07.04.547655 — systems biology — Posted on 2023-07-04
3833 Transcriptional clusters follow a conserved condensation-dispersal sequence during stem cell differentiation
Klingberg, T.; Wachter, I.; Pancholi, A.; Gohar, Y.; Kumar, P.; Sobucki, M.; Kämmer, E.; Eroglu-Kayikci, S.; Erhardt, S.; Ferrai, C.; Zaburdaev, V.; Hilbert, L.
10.1101/2023.07.04.547621 — developmental biology — Posted on 2023-07-04
3834 An ancient split of germline and somatic stem cell lineages in Hydra
Nishimiya-Fujisawa, C.; Petersen, H.; Koubkova-Yu, T. C.-T.; Noda, C.; Shigenobu, S.; Bageritz, J.; Fujisawa, T.; Simakov, O.; Kobayashi, S.; Holstein, T. W.
10.1101/2023.07.04.546637 — developmental biology — Posted on 2023-07-04
3836 Structure of a membrane-bound menaquinol:organohalide oxidoreductase
Cimmino, L.; Duarte, A. G.; Ni, D.; Ekundayo, B. E.; Pereira, I. A. C.; Stahlberg, H.; Holliger, C.; Maillard, J.
10.1101/2023.07.04.547610 — microbiology — Posted on 2023-07-04
3841 A fungal pathogen manipulates phytocytokine signaling for plant infection
Hua, C.; Zhang, L.; Stintzi, A.; Schaller, A.; Guo, H.-S.; Nuernberger, T.
10.1101/2023.07.04.547642 — plant biology — Posted on 2023-07-04
3842 Cancer-specific association between Tau (MAPT) and cellular pathways, clinical outcome, and drug response
Callari, M.; Sola, M.; Magrin, C.; Rinaldi, A.; Bolis, M.; Paganetti, P.; Colnaghi, L.; Papin, S.
10.1101/2023.07.04.547660 — cancer biology — Posted on 2023-07-04
3844 Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
Akshay, A.; Katoch, M.; Shekarchizadeh, N.; Abedi, M.; Sharma, A.; C. Burkhard, F.; M. Adam, R.; Monastyrskaia, K.; Hashemi Gheinani, A.
10.1101/2023.07.04.546825 — bioinformatics — Posted on 2023-07-04
3847 The structure of a novel ferredoxin: FhuF, a ferric-siderophore reductase from E. coli K-12 with a novel 2Fe-2S cluster coordination
Trindade, I. B.; Rollo, F.; Todorovic, S.; Catarino, T.; Moe, E.; Matias, P. M.; Piccioli, M.; Louro, R. O.
10.1101/2023.07.04.547673 — biochemistry — Posted on 2023-07-04
3848 Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium
Miro-Pina, C.; Arnaiz, O.; de Vanssay, A.; Frapporti, A.; Charmant, O.; Humbert, A.; Lhuillier-Akakpo, M.; Duharcourt, S.
10.1101/2023.07.04.547679 — genomics — Posted on 2023-07-04
3851 Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis
Ofoghi, A.; Kotschi, S.; Lemmer, I. L.; Haas, D. T.; Willemsen, N.; Bayer, B.; Moeller, S.; Haberecht-Mueller, S.; Krueger, E.; Krahmer, N.; Bartelt, A.
10.1101/2023.07.04.547652 — molecular biology — Posted on 2023-07-04
3852 Characterization of GEXP15 as a potential regulator of Protein Phosphatase 1 and partner of ribosomal complex in Plasmodium falciparum.
Mansour, H.; Cabezas-Cruz, A.; Peucelle, V.; Farce, A.; Salome-Desnoulez, S.; Metatla, I.; Guerrera, I. C.; Hollin, T.; Khalife, J.
10.1101/2023.07.04.547663 — microbiology — Posted on 2023-07-04
3855 Balance of AKT isoforms in intestinal barrier function. Implications for IBD therapy.
Garcia Prieto, T.; Barbachano, A.; Cuesta, N. G.; SANCHEZ GONZALEZ, D.; Arranz, A.; Fresno, M.
10.1101/2023.07.04.547629 — immunology — Posted on 2023-07-04
3856 AMPK activation induces RALDHhigh tolerogenic dendritic cells through rewiring of glucose and lipid metabolism
Brombacher, E. C.; Patente, T. A.; van der Ham, A. J.; Moll, T. J. A.; Otto, F.; Verheijen, F. W. M.; Zaal, E. A.; de Ru, A. H.; Tjokrodirijo, R. T. N.; Berkers, C. R.; van Veelen, P. A.; Guigas, B.; Everts, B.
10.1101/2023.07.04.547639 — immunology — Posted on 2023-07-04
3857 Human vagus nerve fascicular anatomy: a microCT segmentation and histological study
Thompson, N.; Mastitskaya, S.; Iacoviello, F.; Shearing, P. R.; Aristovich, K.; Holder, D.
10.1101/2023.07.04.547643 — neuroscience — Posted on 2023-07-04
3858 Aged male and female Panx3 KO mice develop severe osteoarthritis independent of forced mechanical use.
Wakefield, B.; Hutchinson, J. L.; Kanji, R.; Herold, G.; Tang, J.; O'Donnell, B. L.; Brooks, C.; Kiser, P.; Grol, M.; Seguin, C. A.; Beier, F.; Penuela, S.
10.1101/2023.07.04.547676 — physiology — Posted on 2023-07-04
3861 Molecular Dynamics Simulations on Quercetin-3-(6-Malonylglucoside) From Morus alba Shows Optimal Inhibition of Bcl-2 with Favorable Anti-Tumor Activities.
Omirin, E. S.; Omotuyi, O.; Afokhume, O. G.; Okoh, E. F.; Boboye, S. O.; Olugbogi, E. A.; Adelegan, O. O.; Ibitoye, B. O.; Aderiye, M. A.; Agosile, O. O.
10.1101/2023.07.04.547659 — bioinformatics — Posted on 2023-07-04
3862 Comparison of robotic automated and manual injection methods in zebrafish embryos for high throughput RNA silencing using CRISPR-CasRx
Abugattas-Nunez Del Prado, J.; Ding, Y.; de Sonneville, J.; van der Kolk, K.-J.; Moreno-Mateos, M. A.; Malaga-Trillo, E.; Spaink, H. P.
10.1101/2023.07.04.547651 — bioengineering — Posted on 2023-07-04
3863 Divergence and gene flow history at two large chromosomal inversions involved in long-snouted seahorse ecotype formation
Meyer, L. M.; Barry, P.; Riquet, F.; Foote, A.; Der Sarkissian, C.; Cunha, R.; Arbiol, C.; Cerqueira, F.; Desmarais, E.; Bordes, A.; Bierne, N.; Guinand, B.; Gagnaire, P.-A.
10.1101/2023.07.04.547634 — genomics — Posted on 2023-07-04
3866 A matrisome atlas of germ cell development
Amran, A.; Pigatto, L.; Farley, J.; Godini, R.; Pocock, R.; Gopal, S.
10.1101/2023.07.04.547647 — cell biology — Posted on 2023-07-04
3868 Dynamic ventral disc contraction is necessary for Giardia attachment and host pathology
Nosala, C.; Hagen, K. D.; Guest, S. L.; Hilton, N. A.; Mueller, A.; Laue, M.; Klotz, C.; Aebischer, A.; Dawson, S. C.
10.1101/2023.07.04.547600 — microbiology — Posted on 2023-07-04
3870 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles
Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.
10.1101/2023.07.04.547323 — neuroscience — Posted on 2023-07-04
3873 Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species
Green, A. P.; Klimm, F.; Marshall, A. S.; Leetmaa, R.; Aryaman, J.; Gomez-Duran, A.; Chinnery, P. F.; Jones, N. S.
10.1101/2023.07.04.547509 — bioinformatics — Posted on 2023-07-04
3876 Brain-wide representations of prior information in mouse decision-making
Findling, C.; Hubert, F.; International Brain Laboratory, ; Acerbi, L.; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Latham, P. E.; Lau, P. Y. P.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Paninski, L.; Pan-Vazquez, A.; Pillow, J.; Rossant, C.; Roth, N.; Schaeffer, R.; Schartn
10.1101/2023.07.04.547684 — neuroscience — Posted on 2023-07-04
3878 Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils
Desai, A. A.; Zupancic, J. M.; Trzeciakiewicz, H.; Gerson, J. E.; DuBois, K. N.; Skinner, M. E.; Sharkey, L. M.; McArthur, N.; Ferris, S. P.; Bhatt, N. N.; Makowski, E. K.; Smith, M. D.; Chen, H.; Huang, J.; Jerez, C.; Kane, R. S.; Kanaan, N. M.; Paulson, H. L.; Tessier, P. M.
10.1101/2023.07.04.547698 — bioengineering — Posted on 2023-07-04
3879 Adaptative Laboratory Evolution reveals biofilm regulating genes as key players in B. subtilis root colonization
Pomerleau, M.; Charron-Lamoureux, V.; Leonard, L.; Grenier, F.; Rodrigue, S.; Beauregard, P. B.
10.1101/2023.07.04.547689 — microbiology — Posted on 2023-07-04
3880 A Brain-Wide Map of Neural Activity during Complex Behaviour
International Brain Lab, ; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; Dayan, P.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Findling, C.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Hubert, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Lau, P. Y. P.; Mainen, Z. F.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Pan-Vazquez, A.; Pouget, A.; Rossant, C.; Roth, N.; Schaeffer, R.; Schartner, M.; Shi, Y.; Socha
10.1101/2023.07.04.547681 — neuroscience — Posted on 2023-07-04
3882 Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis
Inamo, J.; Keegan, J.; Griffith, A.; Ghosh, T.; Horisberger, A.; Howard, K.; Pulford, J.; Murzin, E.; Hancock, B.; Jonsson, A. H.; Seifert, J.; Feser, M. L.; Norris, J. M.; Cao, Y.; Apruzzese, W.; Bridges, S. L.; Bykerk, V.; Goodman, S.; Donlin, L.; Firestein, G. S.; Perlman, H.; Bathon, J. M.; Hughes, L. B.; Tabechian, D.; Filer, A.; Pitzalis, C.; H. Anolik, J.; Moreland, L.; Guthridge, J. M.; James, J. A.; Brenner, M. B.; Raychaudhuri, S.; Sparks, J. A.; The Accelerating Medicines Partnership RA/SLE Network, ; Holers, V. M.; Deane, K. D.; Lederer, J. A.; Rao, D. A.; Zhang, F.
10.1101/2023.07.03.547507 — genomics — Posted on 2023-07-04
3884 Synaptogyrin regulates neuronal activity dependent autophagy to degrade synaptic vesicle components and pathological Tau
Hernandez-Diaz, S.; Martinez-Olondo, P.; Sanchez-Mirasierra, I.; Montecinos-Oliva, C.; Ghimire, S.; Soukup, S.
10.1101/2023.07.04.547658 — neuroscience — Posted on 2023-07-04
3887 Mapping viscosity in discrete subcellular locations with a BODIPY based fluorescent probe
Pytowski, L.; Foley, A. C.; Hernandez, Z.; Moon, N.; Donohoe, T. J.; Vaux, D. J.
10.1101/522532 — cell biology — Posted on 2023-07-04
3890 Mechanosensing and Sphingolipid-Docking Mediate Lipopetide-Induced Immunity in Arabidopsis
Prsic, J.; Gilliard, G.; Ibrahim, H.; Arguelles Arias, A.; Rondelli, V.; Crowet, J.-M.; Genva, M.; Luzuriaga Loaiza, W. P.; Deboever, E.; Nasir, N.; Lins, L.; Mathelie-Guinlet, M.; Eschrig, S.; Ranf, S.; Dorey, S.; De Coninck, B.; Nurnberger, T.; Mongrand, S.; Hofte, M.; Zipfel, C.; Dufrene, Y.; Deleu, M.; Ongena, M.
10.1101/2023.07.04.547613 — plant biology — Posted on 2023-07-04
3894 ANGPTL8 R59W variant influences inflammation through modulating NF-κB pathway under TNFα stimulation
Abu-Farha, M.; Madhu, D.; Hebbar, P.; Mohammad, A.; Channanath, A.; Kavalakatt, S.; Alam-Eldin, N.; Alterki, F.; Taher, I.; Alsmadi, O.; Shehab, M.; Arefanian, H.; Ahmad, R.; Al-Mulla, F.; Thanaraj, T. A.; Abubaker, J.
10.1101/2023.07.04.547624 — biochemistry — Posted on 2023-07-04
3895 Transcriptome brings variations of gene expression, alternative splicing, and structural variations into gene-scale trait dissection in soybean
Li, D.; Wang, Q.; Tian, Y.; Lyu, X.; Zhang, H.; Sun, Y.; Hong, H.; Gao, H.; Li, Y.-F.; Zhao, C.; Wang, J.; Wang, R.; Yang, J.; Liu, B.; Schnable, P. S.; Schnable, J. C.; Li, Y.; Qiu, L.
10.1101/2023.07.03.545230 — genetics — Posted on 2023-07-04
3896 Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.
Richard, E.; Darracq, B.; Littner, E.; Vit, C.; Whiteway, C.; Bos, J.; Fournes, F.; Garriss, G.; Conte, V.; Lapaillerie, D.; Parissi, V.; Rousset, F.; Skovgaard, O.; Bikard, D.; Rocha, E.; Mazel, D.; Loot, C.
10.1101/2022.08.03.502626 — genetics — Posted on 2023-07-04
3901 Curated Single Cell Multimodal Landmark Datasets for R/Bioconductor
Eckenrode, K.; Righelli, D.; Ramos, M.; Argelaguet, R.; Vanderaa, C.; Geistlinger, L.; Culhane, A.; Gatto, L.; Carey, V. J.; Morgan, M.; Risso, D.; Waldron, L. D.
10.1101/2021.10.27.466079 — bioinformatics — Posted on 2023-07-04
3904 Comparison of metabarcoding taxonomic markers to describe fungal communities in fermented foods
Rue, O.; Cotton, M.; Dugat-Bony, E.; Howell, K.; Irlinger, F.; Legras, J.-L.; Loux, V.; Michel, E.; Mounier, J.; Neuveglise, C.; Sicard, D.
10.1101/2023.01.13.523754 — microbiology — Posted on 2023-07-04
3905 Uncovering the cis-regulatory program of early human B-cell commitment and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia
Planell, N.; Martinez-de-Morentin, X.; Mouzo, D.; Lara-Astiaso, D.; Vilas-Zornoza, A.; San Martin-Uriz, P.; Alignani, D.; Paiva, B.; Maillo, A.; Kurowska, A.; Urdangarin, A.; Noori, P.; Ortega-Legarreta, A.; Hernaez, M.; Lagani, V.; Kiani, N.; Martin-Subero, J. I.; Ramirez, R. N.; Tegner, J.; Prosper, F.; Gomez-Cabrero, D.
10.1101/2023.07.01.547234 — immunology — Posted on 2023-07-04
3915 Recent land use and land cover pressures on Iberian peatlands
Fernandes, R.; Geraldes, M.; Marchante, E.; Duran, J.; Capinha, C.
10.1101/2023.07.03.547480 — ecology — Posted on 2023-07-04
3917 Direct recruitment of Mis18 to interphase spindle poles promotes CENP-A chromatin assembly
London, N.; Median-Pritchard, B.; Spanos, C.; Rappsilber, J.; Jeyaprakash, A. A.; Allshire, R.
10.1101/2023.07.03.547485 — cell biology — Posted on 2023-07-04
3919 Auditory cortex anatomy reflects multilingual phonological experience
Kepinska, O.; Dalboni da Rocha, J.; Tuerk, C.; Hervais-Adelman, A.; Bouhali, F.; Green, D.; Price, C. J.; Golestani, N.
10.1101/2023.06.16.545298 — neuroscience — Posted on 2023-07-04
3920 Small proteins modulate ion channel-like ACD6 to regulate immunity in Arabidopsis thaliana
Chen, J.; Li, L.; Kim, J.; Neuhaeuser, B.; Wang, M.; Thelen, M.; Hilleary, R.; Chi, Y.; Wei, L.; Venkataramani, K.; Exposito-Alonso, M.; Liu, C.; Keck, J.; Barragan, A. C.; Schwab, R.; Lutz, U.; Pei, Z.; He, S.-Y.; Ludewig, U.; Weigel, D.; Zhu, W.
10.1101/2021.01.25.428077 — plant biology — Posted on 2023-07-04
3926 A multidimensional assessment of in-host fitness costs of drug resistance in the opportunistic fungal pathogen Candida glabrata
Arastehfar, A.; Daneshnia, F.; Hovhannisyan, H.; Cabrera, N.; Ilkit, M.; Desai, J.; Gabaldon, T.; Shor, E.; Perlin, D.
10.1101/2023.07.03.547612 — microbiology — Posted on 2023-07-04
3934 The complete mitochondrial genome of Spurilla braziliana MacFarland 1909 (Nudibranchia, Aeolidiidae).
Mizobata, H.; Hayashi, K.; Yonezawa, R.; Lanza, A.; Kinoshita, S.; Yoshitake, K.; Asakawa, S.
10.1101/2023.04.04.535430 — genomics — Posted on 2023-07-04
3935 Environmental effects on genetic variance are likely to constrain adaptation in novel environments
Walter, G. M.; Monro, K.; Terranova, D.; la Spina, E.; Majorana, M. G.; Pepe, G.; Clark, J.; Cozzolino, S.; Cristaudo, A.; Hiscock, S. J.; Bridle, J. R.
10.1101/2021.02.08.430333 — evolutionary biology — Posted on 2023-07-04
3937 BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolism
Zhang, Z.; Liao, Q.; Pan, T.; Yu, L.; Luo, Z.; Su, S.; Liu, S.; Hou, M.; Li, Y.; Damba, T.; Liang, Y.; Zhou, L.
10.1101/2023.04.18.537352 — molecular biology — Posted on 2023-07-04
3938 Speech prosody enhances the neural processing of syntax
Degano, G.; Donhauser, P.; Gwilliams, L.; Merlo, P.; Golestani, N.
10.1101/2023.07.03.547482 — neuroscience — Posted on 2023-07-04
3939 Traditional Norwegian Kveik Yeast: An Ancient Sister Group to Domesticated Saccharomyces cerevisiae
Dondrup, M.; Eiken, H. G.; Martinussen, A. O.; Haugland, L. K.; Holdhus, R.; Dolan, D.; Grellscheid, S.; Hagen, S.; Elameen, A.; Myking, T.
10.1101/2023.07.03.547515 — genomics — Posted on 2023-07-03
3942 Enamel proteins reveal biological sex and genetic variability within southern African Paranthropus
Madupe, P. P.; Koenig, C.; Patramanis, I.; Rüther, P. L.; Hlazo, N.; Mackie, M.; Tawane, M.; Krueger, J.; Taurozzi, A. J.; Troche, G. B.; Kibii, J.; Pickering, R.; Dickinson, M. R.; Sahle, Y.; Kgotleng, D.; Musiba, C.; Manthi, F.; Bell, L.; du Plessis, M.; Gilbert, C.; Zipfel, B.; Kuderna, L.; Lizano, E.; Welker, F.; Kyriakidou, P.; Cox, J.; Mollereau, C.; Tokarski, C.; Blackburn, J.; Ramos-Madrigal, J.; Marques-Bonet, T.; Penkman, K. E. H.; Zanolli, C.; Schroeder, L.; Racimo, F.; Olsen, J. V.; Ackermann, R. R.; Cappellini, E.
10.1101/2023.07.03.547326 — evolutionary biology — Posted on 2023-07-03
3943 Competition for light can drive adverse species-composition shifts in the Amazon Forest under elevated CO2
Joshi, J.; Hofhansl, F.; Singh, S.; Stocker, B.; Brännström, A.; Franklin, O.; Blanco, C. C.; Aleixo, I. F.; Lapola, D. M.; Prentice, I. C.; Dieckmann, U.
10.1101/2023.07.03.547575 — ecology — Posted on 2023-07-03
3944 Valence and salience encoding by parallel circuits from the paraventricular thalamus to the nucleus accumbens
Rivera-Irizarry, J. K.; Hamor, P. U.; Rowson, S. A.; Asfouri, J.; Liu, D.; Zallar, L. J.; Garcia, A. F.; Skelly, M. J.; Pleil, K. E.
10.1101/2023.07.03.547570 — neuroscience — Posted on 2023-07-03
3949 Intradisciplinary Growth of Sustainability-Minded Engineers through Conservation Technology
Schulz, A. K.; Shriver, C.; Patka, A.; Greiner, C.; Seleb, B.; Watts Hull, R.; Subino Sullivan, C.; Sonnenberg-Klein, J.; Moore, R.
10.1101/2023.07.03.546429 — scientific communication and education — Posted on 2023-07-03
3951 β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain
Madhavan, S. S.; Roa Diaz, S.; Peralta, S.; Nomura, M.; King, C. D.; Lin, A.; Bhaumik, D.; Shah, S.; Blade, T.; Gray, W.; Chamoli, M.; Eap, B.; Panda, O.; Diaz, D.; Garcia, T. Y.; Stubbs, B. J.; Lithgow, G. J.; Schilling, B.; Verdin, E.; Chaudhuri, A.; Newman, J. C.
10.1101/2023.07.03.547547 — physiology — Posted on 2023-07-03
3953 PanTA: An ultra-fast method for constructing large and growing microbial pangenomes
Le, D. Q.; Nguyen, T. A.; Nguyen, T. T.; Do, V. H.; Nguyen, C. H.; Phung, H. T.; Ho, T. H.; Vo, N. S.; Nguyen, T.; Nguyen, H. A.; Cao, M. D.
10.1101/2023.07.03.547471 — bioinformatics — Posted on 2023-07-03
3955 Effect of Aging on the Human Myometrium at Single-Cell Resolution
Punzon-Jimenez, P.; Machado-Lopez, A.; Perez-Moraga, R.; Llera-Oyola, J.; Grases, D.; Galvez-Viedma, M.; AlSibai, M.; Satorres, E.; Badenes, R.; Ferrer, C.; Porta-Pardo, E.; Roson, B.; Simon, C.; Mas, A.
10.1101/2023.07.03.547452 — cell biology — Posted on 2023-07-03
3956 Structure and engineering of miniature Acidibacillus sulfuroxidans Cas12f1
Wu, Z.; Liu, D.; Pan, D.; Yu, H.; Shi, J.; Ma, J.; Fu, W.; Wang, Z.; Zheng, Z.; Qu, Y.; Li, F.; Chen, W.; Huang, X.; Shen, H.; Ji, Q.
10.1101/2023.07.03.547593 — molecular biology — Posted on 2023-07-03
3959 Serotonergic modulation of the BNST-CeA circuit promotes sex differences in fear learning
Ravenelle, R.; Fernandes-Henriques, C.; Lee, J.; Liu, J.; Likhtik, E.; Burghardt, N. S.
10.1101/2023.07.03.547577 — neuroscience — Posted on 2023-07-03
3960 Human HPSE2 gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndrome.
Lopes, F. M.; Grenier, C.; Jarvis, B. W.; Al Mahdy, S.; Lene-Mckay, A.; Gurney, A. M.; Newman, W. G.; Waddington, S. N.; Woolf, A. S.; Roberts, N. A.
10.1101/2023.07.03.547034 — neuroscience — Posted on 2023-07-03
3965 ASD mutation of Katnal2 impairs ependymal ciliary motion and causes hydrocephalus
Qiu, S.; Cao, H.; Xue, Y.; Zhao, W.; Xie, S.; Wu, N.; Song, M.; Pan, Y.-H.; Baas, P. W.; Ma, J.; Yuan, X.-B.
10.1101/2023.07.03.547302 — neuroscience — Posted on 2023-07-03
3970 Microbiome Prevents Sudden Death Through Occult Cardiac Sub-micrometastasis in Mice
Aalam, S. M. M.; Tang, X.; PS, H.; Salem, S. M.; Al-jarrad, A.; Noseworthy, P. A.; Behfar, A.; Sadanandam, A.; Kalari, K. R.; Kashyap, P. C.; Kannan, N.
10.1101/2023.07.03.547566 — cancer biology — Posted on 2023-07-03
3971 Autoencoder Model for Translating Omics Signatures
Meimetis, N.; Pullen, K. M.; Zhu, D. Y.; Nilsson, A.; Hoang, T. N.; Magliacane, S.; Lauffenburger, D. A.
10.1101/2023.06.08.544243 — bioinformatics — Posted on 2023-07-03
3973 Subcellular sampling and sequencing by iSCseq connects transcriptomics with morphological, physical, and physiological findings
Okada, H.; Terui, Y.; Omata, Y.; Seki, M.; Tani, S.; Terashima, A.; Kanazawa, S.; Hosonuma, M.; Miyahara, J.; Makabe, K.; Onodera, S.; Yano, F.; Kajiya, H.; Gori, F.; Saito, T.; Suzuki, Y.; Okabe, K.; Baron, R.; Chung, U.-i.; Tanaka, S.; Hojo, H.
10.1101/2022.09.05.506360 — genomics — Posted on 2023-07-03
3974 FAP106 is an interaction hub required for assembly of conserved and lineage-specific microtubule inner proteins at the cilium inner junction
Shimogawa, M. M.; Wijono, A. S.; Wang, H.; Zhang, J.; Sha, J.; Szombathy, N.; Vadakkan, S.; Pelayo, P.; Jonnalagadda, K.; Wohlschlegel, J. A.; Zhou, Z. H.; Hill, K.
10.1101/2022.11.11.516029 — cell biology — Posted on 2023-07-03
3975 ent-Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice
Gochman, A.; Do, T. Q.; Kim, K.; Schwarz, J. A.; Thorpe, M. P.; Blackwell, D. J.; Smith, A. N.; Akers, W. S.; Cornea, R. L.; Laver, D. L.; Johnston, J. N.; Knollmann, B. C.
10.1101/2023.07.03.547578 — pharmacology and toxicology — Posted on 2023-07-03
3976 A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies
Yang, D.; Beddows, I.; Tang, H.; Cascio, S.; McGonigal, S. C.; Bai, S.; Johnson, B. K.; Powers, J. J.; Acharya, R.; Bao, R. K.; Bruno, T.; Soong, T.; Conejo-Garcia, J. R.; Shen, H.; Bility, M. T.; Buckanovich, R.
10.1101/2023.07.03.547206 — cancer biology — Posted on 2023-07-03
3977 Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex
vadla, r.; Miki, S.; Taylor, B.; Kawauchi, D.; Jones, B. M.; Nathwani, N.; Pham, P.; Tsang, J.; Nathanson, D. A.; Furnari, F. B.
10.1101/2023.07.03.546613 — cancer biology — Posted on 2023-07-03
3978 Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies
Lehman, S. J.; Meller, A.; Solieva, S. O.; Lotthammer, J. M.; Greenberg, L.; Langer, S. J.; Greenberg, M. J.; Tardiff, J. C.; Bowman, G. R.; Leinwand, L. A.
10.1101/2023.07.03.547580 — biophysics — Posted on 2023-07-03
3982 Establishing RNAge to score cellular aging and rejuvenation paradigms and identify novel age-modulating compounds
Zhang, C.; Saurat, N.; Cornacchia, D.; Chung, S. Y.; Skider, T.; Minotti, A.; Studer, L.; Betel, D.
10.1101/2023.07.03.547539 — cell biology — Posted on 2023-07-03
3985 Emergence of putative energy parasites within Clostridia revealed by genome analysis of a novel endosymbiotic clade
Takahashi, K.; Kuwahara, H.; Horikawa, Y.; Izawa, K.; Kato, D.; Inagaki, T.; Yuki, M.; Ohkuma, M.; Hongoh, Y.
10.1101/2023.07.03.547156 — microbiology — Posted on 2023-07-03
3986 Host specificity shapes fish viromes across lakes on an isolated remote island
Grimwood, R. M.; Fortune-Kelly, G.; Holmes, E. C.; Ingram, T.; Geoghegan, J. L.
10.1101/2023.07.03.547585 — microbiology — Posted on 2023-07-03
3988 Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors
Schietinger, A.; Espinosa-Carrasco, G.; Dave, A.; Scrivo, A.; Lee, H.-S.; Burt, B. M.; Zumbo, P.; Betel, D.; Hellmann, M.
10.1101/2023.07.03.547423 — immunology — Posted on 2023-07-03
3989 Ym1 protein crystals promote type 2 immunity
Heyndrickx, I.; Deswarte, K.; Verstraete, K.; Verschueren, K.; Smole, U.; Aegerter, H.; Dansercoer, A.; Hammad, H.; Savvides, S.; Lambrecht, B.
10.1101/2023.07.03.547463 — immunology — Posted on 2023-07-03
3990 Activity-Induced MeCP2 Phosphorylation Regulates Retinogeniculate Synapse Refinement
Tzeng, C. P.; Whitwam, T.; Boxer, L. D.; Li, E.; Silberfeld, A.; Trowbridge, S.; Mei, K.; Lin, C.; Shamah, R.; Griffith, E. C.; Renthal, W.; Chen, C.; Greenberg, M. E.
10.1101/2023.07.03.547549 — neuroscience — Posted on 2023-07-03
3993 Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila
Penner, T. V.; Lorente Cobo, N.; Patel, D. T.; Patel, D. H.; Savchenko, A.; Brassinga, A. K. C.; Prehna, G.
10.1101/2023.07.03.547437 — biochemistry — Posted on 2023-07-03
3994 Absence of Coronavirus in terns in the Western Indian Ocean?
Lebarbenchon, C.; Feare, C.; Larose, C.; Boucher, S.; Jaeger, A.; Le Corre, M.
10.1101/2023.06.30.547193 — ecology — Posted on 2023-07-03
3996 Alternative cell entry mechanisms for SARS-CoV-2 and multiple animal viruses
Ojha, R.; Jiang, A.; Mantyla, E.; Modhiran, N.; Witte, R.; Gaudin, A.; De Zanetti, L.; Gormal, R.; Vihinen-Ranta, M.; Mercer, J.; Suomalainen, M.; Greber, U. F.; Yamauchi, Y.; Yves-Lozach, P.; Helenius, A.; Vapalahti, O.; Young, P.; Watterson, D.; Meunier, F. A.; Joensuu, M.; Balistreri, G.
10.1101/2023.07.02.547368 — microbiology — Posted on 2023-07-03
3998 Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21
Zachariah, A.; Krishnankutty, S. P.; Manazhi, J.; Omanakuttan, V.; Santosh, S.; Blanchard, A. M.; Tarlinton, R. E.
10.1101/2023.07.03.547244 — microbiology — Posted on 2023-07-03
3999 Covalent macrocyclic proteasome inhibitors mitigate resistance in Plasmodium falciparum
Bennett, J. M.; Ward, K. E.; Muir, R.; Kabeche, S.; Yoo, E.; Yeo, T.; Lam, G.; Berger, G.; Faucher, F. F.; Lin, G.; Gerwick, W. H.; Yeh, E.; Fidock, D. A.; Bogyo, M.
10.1101/2023.07.03.547579 — microbiology — Posted on 2023-07-03
4001 Investigation of swine caecal microbiomes in the northern region of Thailand
Eiamsam-ang, T.; Tadee, P.; Buddhasiri, S.; Chuammitri, P.; Kittiwan, N.; Pascoe, B.; Patchanee, P.
10.1101/2023.07.03.547425 — microbiology — Posted on 2023-07-03
4002 Interrogation of RNA-protein interaction dynamics in bacterial growth
Monti, M.; Herman, R.; Davey, K.; Dawson, C. S.; Ule, J.; Thomas, G. H.; Willis, A. E.; Lilley, K. S.; Villanueva, E.
10.1101/2023.07.03.547468 — microbiology — Posted on 2023-07-03
4003 Antigenic cartography using variant-specific hamster sera reveals substantial antigenic variation among Omicron subvariants
Mühlemann, B.; Trimpert, J.; Walper, F.; Schmidt, M. L.; Schroeder, S.; Jeworowski, L. M.; Beheim-Schwarzbach, J.; Bleicker, T.; Niemeyer, D.; Adler, J. M.; Vidal, R. M.; Langner, C.; Vladimirova, D.; Smith, D. J.; Voss, M.; Paltzow, L.; Martinez Christophersen, C.; Rose, R.; Krumbholz, A.; Jones, T. C.; Corman, V. M.; Drosten, C.
10.1101/2023.07.02.547076 — immunology — Posted on 2023-07-03
4005 RNA structure and multiple weak interactions balance the interplay between RNA binding and phase separation of SARS-CoV-2 nucleocapsid
Estelle, A. B.; Forsythe, H. M.; Yu, Z.; Hughes, K.; Lasher, B.; Allen, P.; Reardon, P. N.; Hendrix, D. A.; Barbar, E. J.
10.1101/2023.07.02.547440 — biophysics — Posted on 2023-07-03
4008 Centriolar subdistal appendages promote double strand break repair through homologous recombination
Rodriguez-Real, G.; Dominguez-Calvo, A.; Prados-Carvajal, R.; Bayona-Feliu, A.; Gomes-Pereira, S.; Balestra, F. R.; Huertas, P.
10.1101/2022.10.19.512819 — cell biology — Posted on 2023-07-03
4009 Dynein and dynactin move long-range but are delivered separately to the axon tip
Fellows, A. D.; Bruntraeger, M.; Burgold, T.; Bassett, A. R.; Carter, A. P.
10.1101/2023.07.03.547521 — cell biology — Posted on 2023-07-03
4010 Mitochondria morphology governs ATP production rate
Garcia, G. C.; Gupta, K.; Bartol, T. M.; Sejnowski, T. J.; Rangamani, P.
10.1101/2022.08.16.500715 — cell biology — Posted on 2023-07-03
4015 Mixed selectivity coding of content-temporal detail by dorsomedial posterior parietal neurons
Wang, L.; Zhou, X.; Zeng, F.; Cao, M.; Zuo, S.; Yang, J.; Kusunoki, M.; Wang, H.; Zhou, Y.-d.; Chen, A.; Kwok, S. C.
10.1101/2022.07.16.500237 — neuroscience — Posted on 2023-07-03
4016 Exploratory Correlation of The Human Structural Connectome with Non-MRI Variables
Aganj, I.; Mora, J.; Frau-Pascual, A.; Fischl, B. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.30.547308 — neuroscience — Posted on 2023-07-03
4017 Comparisons of two receptor pathways in a single cell-type reveal features of signalling specificity.
Ma, Y.; Fluckiger, I.; Nicolet, J.; Pang, J.; Dickinson, J.; De Bellis, D.; Emonet, A.; Fujita, S.; Geldner, N.
10.1101/2023.07.03.547518 — plant biology — Posted on 2023-07-03
4018 Circulating MicroRNAs indicative of sex and stress in the European seabass (Dicentrarchus labrax): toward the identification of new biomarkers.
Houdelet, C.; Blondeau-Bidet, E.; Estevez-Villar, M.; Mialhe, X.; Hermet, S.; Ruelle, F.; Dutto, G.; Bajek, A.; Bobe, J.; Geffroy, B.
10.1101/2023.07.03.547501 — physiology — Posted on 2023-07-03
4019 A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
Uo, T.; Ojo, K. K.; Sprenger, C. C.; Epilepsia, K. S.; Perera, B. G. K.; Damodarasamy, M.; Sun, S.; Kim, S.; Hogan, H. H.; Hulverson, M. A.; Choi, R.; Whitman, G. R.; Barrett, L. K.; Michaels, S. A.; Xu, L. H.; Pang, H. J.; Nguyen, M. M.; Vigil, A.-L. B. G.; Kamat, V.; Sullivan, L. B.; Sweet, I. R.; Vidadala, R.; Maly, D. J.; Van Voorhis, W. C.; Plymate, S. R.
10.1101/2023.07.01.547355 — cancer biology — Posted on 2023-07-03
4022 The full set of potential open regions (PORs) in the human genome defined by consensus peaks of ATAC-seq data
Meng, Q.; Wu, X.; Li, C.; Li, J.; Xi, X.; Chen, S.; Chen, S.; Li, J.; Wang, X.; Jiang, R.; Wei, L.; Zhang, X.
10.1101/2023.05.30.542889 — bioinformatics — Posted on 2023-07-03
4028 SH2 domain protein E (SHE) and ABL signaling regulate blood vessel size
Schumacher, J. A.; Wright, Z. A.; Rufin Florat, D.; Anand, S. K.; Dasyani, M.; Klimkaite, L.; Bredemeier, N. O.; Gurung, S.; Koller, G. M.; Aguera, K. N.; Chadwick, G. P.; Johnson, R. D.; Davis, G. E.; Sumanas, S.
10.1101/2023.07.03.547455 — developmental biology — Posted on 2023-07-03
4029 NOTCH3 signalling controls human trophoblast stem cell expansion and differentiation
Dietrich, B.; Victoria, K.; Lackner, A. I.; Meinhardt, G.; Koo, B.-K.; Pollheimer, J.; Haider, S.; Knoefler, M.
10.1101/2023.07.03.547490 — developmental biology — Posted on 2023-07-03
4032 Direct recruitment of Mis18 to interphase spindle poles promotes CENP-A chromatin assembly
Allshire, R.; Median-Pritchard, B.; Spanos, C.; Rappsilber, J.; Jeyaprakash, A. A.; London, N.
10.1101/2023.07.03.547485 — cell biology — Posted on 2023-07-03
4040 The substrate quality of CK2 target sites has a determinant role on their function and evolution
Bradley, D.; Garand, C.; Belda, H.; Gagnon-Arsenault, I.; Treeck, M.; Elowe, S.; Landry, C.
10.1101/2023.07.03.547533 — evolutionary biology — Posted on 2023-07-03
4042 Distinct genetic origins of eumelanin intensity and barring patterns in cichlid fishes
Brandon, A. A.; Michael, C.; Baez, A. C.; Moore, E. C.; Ciccotto, P. J.; Roberts, N. B.; Roberts, R. B.; Powder, K. E.
10.1101/2023.07.02.547430 — evolutionary biology — Posted on 2023-07-03
4043 A unified framework to identify demographic buffering in natural populations
Santos, G. S.; Gascoigne, S. J. L.; Dias, A. T. C.; Kajin, M.; Salguero-Gomez, R.
10.1101/2023.07.03.547528 — ecology — Posted on 2023-07-03
4044 The architecture of multifunctional ecological networks
Hervias-Parejo, S.; Cuevas-Blanco, M.; Lacasa, L.; Traveset, A.; Donoso, I.; Heleno, R.; Nogales, M.; Rodriguez-Echeverria, S.; Melian, C.; Eguiluz, V. M.
10.1101/2023.07.02.547400 — ecology — Posted on 2023-07-03
4045 Diseased human pancreas and liver microphysiological system for preclinical diabetes research
Rigal, S.; Casas, B.; Kanebratt, K. P.; Wennberg Huldt, C.; Magnusson, L. U.; Mullers, E.; Kalrsson, F.; Clausen, M.; Hansson, S. F.; Jansson Lofmark, R.; Ammala, C.; Marx, U.; Gennemark, P.; Cedersund, G.; Andersson, T. B.; Vilen, L. K.
10.1101/2023.07.03.547412 — cell biology — Posted on 2023-07-03
4046 Novel phosphatidylinositol flippases contribute to phosphoinositide homeostasis in the plasma membrane
Muranaka, Y.; Shigetomi, R.; Iwasaki, Y.; Hamamoto, A.; Nakayama, K.; Takatsu, H.; Shin, H.-W.
10.1101/2023.07.03.547512 — cell biology — Posted on 2023-07-03
4047 Sub-lethal exposure to chlorfenapyr reduces the probability of developing Plasmodium falciparum parasites in surviving Anopheles mosquitoes
Kweyamba, P.; Hofer, L. M.; Kibondo, U. A.; Mwanga, R. Y.; Sayi, R. M.; Matwewe, F.; Austin, J. W.; Stutz, S.; Moore, S. J.; Müller, P.; Tambwe, M. M.
10.1101/2023.07.03.547458 — cell biology — Posted on 2023-07-03
4055 Pan-genome and Haplotype Map of Cultivars and Their Wild Ancestors Provides Insights into Adaptive Evolution of Cassava (Manihot esculenta Crantz)
Xia, Z.; Du, Z.; Zhou, X.; Jiang, S.; Zhu, T.; Wang, L.; Chen, F.; Carvalho, L. J. C. B.; Zou, M.; Becerra, L. A.; Zhang, X.; Xu, L.; Wang, Z.; Chen, M.; Wang, S.; Li, M.; Li, Y.; Wang, H.; Liu, S.; Bao, Y.; Zhao, L.; Zhang, C.; Xiao, J.; Guo, F.; Shen, X.; Lu, C.; Qiao, F.; Ceballos, H.; Yan, H.; Zhang, H.; He, S.; Zhao, W.; Wan, Y.; Chen, Y.; Huang, D.; Li, K.; Liu, B.; Peng, M.; Zhang, W.; Muller, B. L.; Chen, X.; Luo, M.-C.; Xiao, J.; Wang, W.
10.1101/2023.07.02.546475 — systems biology — Posted on 2023-07-03
4058 First-in-human demonstration of floating EMG sensors and stimulators wirelessly powered and operated by volume conduction
Becerra-Fajardo, L.; Minguillon, J.; Krob, M. O.; Rodrigues, C.; Gonzalez-Sanchez, M.; Megia-Garcia, A.; Redondo Galan, C.; Gutierrez Henares, F.; Comerma, A.; del-Ama, A. J.; Gil-Agudo, A.; Grandas, F.; Schneider-Ickert, A.; Oliveira Barroso, F.; Ivorra, A.
10.1101/2023.06.30.547056 — bioengineering — Posted on 2023-07-03
4059 Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution
Yadav, M.; Sarma, P.; Ganguly, M.; Mishra, S.; Maharana, J.; Zaidi, N.; Dalal, A.; Singh, V.; Saha, S.; Mahajan, G.; Sharma, S.; Chami, M.; Banerjee, R.; Shukla, A. K.
10.1101/2023.07.03.547505 — biochemistry — Posted on 2023-07-03
4066 Template switching between the leading and lagging strands at replication forks generates inverted copy number variants through hairpin-capped extrachromosomal DNA
Martin, R.; Espinoza, C. Y.; Large, C. R. L.; Rosswork, J. B.; Van Bruinisse, C.; Miller, A. W.; Sanchez, J. C.; Miller, M.; Paskvan, S.; Alvino, G. M.; Dunham, M. J.; Raghuraman, M. K.; Brewer, B. J.
10.1101/2023.07.03.547456 — genomics — Posted on 2023-07-03
4067 Polygenic basis of strong and rapid flowering time response to environment perturbations in wild Arabidopsis thaliana population
Ji, Y.; Han, Y.; Dai, Y.; Hao, F.; Feng, X.; Chen, Q.; Hao, R.; Chen, Z.; Zhao, W.; Zhang, W.; Si, H.; Zan, Y.
10.1101/2023.07.02.547444 — genetics — Posted on 2023-07-03
4068 Several independent adaptations of archaea to hypersaline environments
Baker, B. A.; Gutierrez-Preciado, A.; Rodriguez del Rio, A.; McCarthy, C.; Lopez-Garcia, P.; Huerta-Cepas, J.; Susko, E.; Roger, A. J.; Eme, L.; Moreira, D.
10.1101/2023.07.03.547478 — evolutionary biology — Posted on 2023-07-03
4069 A single genetic locus lengthens deer mouse burrows via motor pattern evolution
Harringmeyer, O. S.; Hu, C. K.; Metz, H. C.; Mihelic, E. L.; Rosher, C.; Hoekstra, H. E.
10.1101/2023.07.03.547545 — evolutionary biology — Posted on 2023-07-03
4070 Evolutionary origin, population diversity, and diagnostics for a cryptic hybrid pathogen
Steenwyk, J. L.; Knowles, S. L.; Bastos, R.; Balamurugan, C.; Rinker, D.; Mead, M. E.; Roberts, C. D.; Raja, H. A.; Li, Y.; Colabardini, A. C.; Castro, P. A.; Reis, T. F.; Canovas, D.; Sanchez, R. L.; Lagrou, K.; Torrado, E.; Rodrigues, F.; Oberlies, N. H.; Zhou, X.; Goldman, G.; Rokas, A.
10.1101/2023.07.03.547508 — evolutionary biology — Posted on 2023-07-03
4071 Sugar assimilation underlying dietary evolution of Neotropical bats
Camacho, J.; Bernal-Rivera, A.; Robb, S.; Russell, J.; Yi, K.; Tsuchiya, D.; Wang, Y.; Murillo-Garcia, O. E.; Rohner, N.
10.1101/2023.07.02.547432 — evolutionary biology — Posted on 2023-07-03
4072 Juvenile niches select between two distinct development trajectories and symbiosis modes in vent shrimps
Methou, P.; Gueganton, M.; Copley, J. T.; Watanabe, H. K.; Pradillon, F.; Cambon-Bonavita, M.-A.; Chen, C.
10.1101/2023.07.02.547428 — evolutionary biology — Posted on 2023-07-03
4074 Recent land use and land cover pressures on Iberian peatlands
Fernandes, R.; Geraldes, M.; Marchante, E.; Duran, J.; Capinha, C.
10.1101/2023.07.03.547480 — ecology — Posted on 2023-07-03
4075 Contrasting carbon cycle along tropical forest aridity gradients in W Africa and Amazonia
Zhang-Zheng, H.; Adu-Bredu, S.; Duah-Gyamfi, A.; Moore, S.; Addo-Danso, S. D.; Ibrahim, F.; Amissah, L.; Valentini, R.; Djagbletey, G.; Anim-Adjei, K.; Owusu-Afriyie, K.; Gvozdevaite, A.; Ruiz-Jaen, M. C.; Girardin, C. A. J.; Rifai, S.; Dahlsjö, C.; Riutta, T.; Deng, X.; Tang, M.; Sun, Y.; Prentice, I. C.; Menor, I. O.; Malhi, Y.
10.1101/2023.07.02.547401 — ecology — Posted on 2023-07-03
4078 Yeast diversity in open agave fermentations across Mexico
Gallegos-Gasillas, P.; Garcia-Ortega, L. F.; Espinosa-Cantu, A.; Torres-Lagunes, C. G.; Avelar-Rivas, J. A.; Cano-Ricardez, A.; Garcia-Acero, A. M.; Ruiz-Castro, S.; Flores-Barraza, M.; Castillo, A.; Gonzalez-Zozaya, F.; Delgado-Lemus, A.; Molina-Freaner, F.; Jacques-Hernandez, C.; Hernandez-Lopez, A.; Delaye, L.; Aguirre-Dugua, X.; Kirchmayr, M. R.; Morales, L.; Mancera, E.; DeLuna, A.
10.1101/2023.07.02.547337 — microbiology — Posted on 2023-07-03
4080 The domed architecture of Giardias ventral disc is necessary for attachment and host pathogenesis
Hagen, K. D.; Nosala, C.; Hilton, N.; Mueller, A.; Holthaus, D.; Laue, M.; Klotz, C.; Aebischer, A.; Dawson, S. C.
10.1101/2023.07.02.547441 — microbiology — Posted on 2023-07-03
4082 Distinct groups of RNA viruses associated with thermoacidophilic bacteria
Urayama, S.-i.; Fukudome, A.; Hirai, M.; Okumura, T.; Nishimura, Y.; Takaki, Y.; Kurosawa, N.; Koonin, E. V.; Krupovic, M.; Nunoura, T.
10.1101/2023.07.02.547447 — microbiology — Posted on 2023-07-03
4084 Improvement in Neoantigen Prediction via Integration of RNA Sequencing Data for Variant Calling
Nguyen, B. Q. T.; Tran, T. P. D.; Nguyen, H. T.; Nguyen, T. N.; Pham, T. M. Q.; Nguyen, H. T. P.; Tran, D. H.; Nguyen, T. T. V.; Tran, T. S.; Pham, T.-V. N.; Le, M.-T.; Phan, M.-D.; Giang, H.; Nguyen, H.-N.; Tran, L. S.
10.1101/2023.07.02.547404 — immunology — Posted on 2023-07-03
4085 Time-, tissue- and treatment-associated heterogeneity in tumour-residing migratory DCs
Lee, C. Y.; Kennedy, B. C.; Richoz, N.; Tuong, Z. K.; Dean, I.; Gaspal, F.; Li, Z.; Willis, C.; Hasegawa, T.; Whiteside, S. K.; Posner, D. A.; Carlesso, G.; Hammond, S. A.; Dovedi, S.; Roychoudhuri, R.; Withers, D. R.; Clatworthy, M. R.
10.1101/2023.07.03.547454 — immunology — Posted on 2023-07-03
4087 Mechanical Force Imprints Neutrophils to Orchestrate Pulmonary Homeostasis
Wang, J.; Kang, H.; Zhao, W.; Qi, X.; Miao, N.; Bai, W.; Wang, Y.; Yan, K.; Dong, D.; Ye, Y.; Thanabalasuriar, A.; Zhang, D.; Xu, T.; Li, B.; Wang, J.
10.1101/2023.07.03.547316 — immunology — Posted on 2023-07-03
4091 Anti-manic effect of deep brain stimulation of the ventral tegmental area in an animal model of mania induced by methamphetamine
Varela, R. B.; Boeschen, S. L.; Yates, N.; Houghton, T.; Blaha, C. D.; Lee, K. H.; Bennet, K. E.; Kouzani, A. Z.; Berk, M.; Quevedo, J.; Valvassori, S. S.; Tye, S. J.
10.1101/2023.07.02.547148 — neuroscience — Posted on 2023-07-03
4095 LRP1 mediates leptin transport by coupling with the short-form leptin receptor in the choroid plexus
Uner, A. A.; Yang, W.-M.; Kang, M.-C.; Rodrigues, K. C. d. C.; Aydogan, A.; Seo, J. A.; Mendes, N. F.; Kim, M.-S.; Timzoura, F. E.; Holtzman, M. J.; Lehtinen, M.; Prevot, V.; Kim, Y.-B.
10.1101/2023.07.03.547520 — neuroscience — Posted on 2023-07-03
4096 Role of Articulatory Motor Networks in Perceptual Categorization of Speech Signals: A 7 T fMRI Study
Lankinen, K.; Ahveninen, J.; Uluc, I.; Daneshzand, M.; Mareyam, A.; Kirsch, J. E.; Polimeni, J. R.; Healy, B. C.; Tian, Q.; Khan, S.; Nummenmaa, A.; Wang, Q.-M.; Green, J. R.; Kimberley, T. J.; Li, S.
10.1101/2023.07.02.547409 — neuroscience — Posted on 2023-07-03
4098 Local Orchestration of Global Functional Patterns Supporting Loss and Restoration of Consciousness in the Primate Brain
Luppi, A. I.; Uhrig, L. I.; Tasserie, J.; Signorelli, C. M.; Stamatakis, E. A.; Destexhe, A.; Jarraya, B.; Cofre, R.
10.1101/2023.06.30.547281 — neuroscience — Posted on 2023-07-03
4099 The Symptomatology and Diagnosis of Domoic Acid Toxicosis in Stranded California Sea Lions (Zalophus californianus): A Review and Evaluation of 20 Years of Cases to Guide Prognosis
McClain, A. M.; Field, C. L.; Norris, T. A.; Borremans, B.; Duignan, P. J.; Johnson, S. P.; Whoriskey, S. T.; Thompson-Barbosa, L.; Gulland, F. M. D.
10.1101/2023.07.02.547442 — zoology — Posted on 2023-07-03
4100 Inference for entomological semi-field experiments: Fitting a mathematical model assessing personal and community protection of vector-control interventions
Fairbanks, E. L.; Saeung, M.; Pongsiri, A.; Vajda, E.; Wang, Y.; McIver, D. J.; Tatarsky, A.; Lobo, N. F.; Moore, S. J.; Ponlawat, A.; Chareonviriyaphap, T.; Ross, A.; Chitnis, N.
10.1101/2023.06.30.547223 — systems biology — Posted on 2023-07-03
4102 Longitudinal hair cortisol in bipolar disorder and a mechanism based on HPA dynamics
Milo, T.; Maimon, L.; Cohen, B.; Haran, D.; Segman, D.; Danon, T.; Bren, A.; Mayo, A.; Cohen Rappaport, G.; McInnis, M.; Alon, U.
10.1101/2023.07.03.546860 — systems biology — Posted on 2023-07-03
4104 Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells
Allen, K.; Torres-Velarde, J. M.; Vazquez, J. M.; Moreno-Santillan, D. D.; Sudmant, P. H.; Vazquez-Medina, J. P.
10.1101/2023.07.01.547248 — physiology — Posted on 2023-07-03
4106 Unifying design principles of endocrine gland mass and its regulatory circuits
Raz, M.; Milo, T.; Korem Kohanim, Y.; karin, O.; Tendler, A.; Bar, A.; Glass, D. S.; Mayo, A.; Alon, U.
10.1101/2023.07.03.547486 — physiology — Posted on 2023-07-03
4107 KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development
Tinsley, S. L.; Shelley, R. A.; Mall, G. K.; Chianis, E. R. D.; Dhiman, A.; Baral, G.; Kothandaraman, H.; Thoma, M. C.; Daniel, C.; Lanman, N. A.; Pasca di Magliano, M.; Narla, G.; Solorio, L.; Dykhuizen, E.; Sears, R. C.; Allen-Petersen, B.
10.1101/2023.07.01.547283 — cancer biology — Posted on 2023-07-03
4109 Microenvironmental Stiffness Induces Metabolic Reprogramming in Glioblastoma
Sohrabi, A.; Lefebvre, A. E. Y. T.; Harrison, M. J.; Condro, M. C.; Sanazzaro, T. M.; Safarians, G.; Solomon, I.; Bastola, S.; Kordbacheh, S.; Toh, N.; Kornblum, H. I.; Digman, M. A.; Seidlits, S. K.
10.1101/2023.07.03.547558 — cancer biology — Posted on 2023-07-03
4110 Bestrophin-4 relays Hes4 and interacts with Twist1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells
Wang, Z.; Xia, B.; Qi, S.; Zhang, X.; Zhang, X.; Li, Y.; Wang, H.; Zhang, M.; Zhao, Z.; Kerr, D.; Yang, L.; Cai, S.; Yang, J.
10.1101/2023.07.03.547525 — cancer biology — Posted on 2023-07-03
4111 Head and neck cancer cells terminally differentiate reflecting their tissue of origin: a rationale for differentiation therapies
Oppel, F.; Gendreizig, S.; Martinez-Ruiz, L.; Florido, J.; Lopez-Rodriguez, A.; Pabla, H.; Loganathan, L.; Hose, L.; Kuehnel, P.; Schmidt, P.; Schuermann, M.; Neumann, J. M.; Viyof Ful, F.; Scholtz, L. U.; Ligum, D.; Brasch, F.; Niehaus, K.; Escames, G.; Busche, T.; Kalinowski, J.; Goon, P.; Sudhoff, H.
10.1101/2023.06.30.547265 — cancer biology — Posted on 2023-07-03
4112 Effect of Water Fluoridation on VM-M3 Tumor Metastasis
Seyfried, T. N.; Mastellone, G. M.; Ta, N. L.; Mukherjee, P.; Lee, D. C.; Maurer, J. H.
10.1101/2023.06.30.547222 — cancer biology — Posted on 2023-07-03
4115 Polarization and motility of one-dimensional multi-cellular trains
Ron, J. E.; d'Alesandro, J.; Cellerin, V.; Voituriez, R.; Ladoux, B.; Gov, N. S.
10.1101/2023.07.02.547405 — biophysics — Posted on 2023-07-03
4118 Reconstructing the Transcriptional Regulatory Network of Probiotic L. reuteri is Enabled by Transcriptomics and Machine Learning
Josephs-Spaulding, J.; Rajput, A.; Hefner, Y.; Szubin, R.; Balasubramanian, A.; Li, G.; Zielinski, D. C.; Jahn, L.; Sommer, M.; Phaneuf, P.; Palsson, B. O.
10.1101/2023.07.03.547516 — bioinformatics — Posted on 2023-07-03
4119 Identification and characterization of specific motifs in effector proteins of plant parasites using MOnSTER.
Calia, G.; Porracciolo, P.; Kozlowski, D.; Schuler, H.; Cestaro, A.; Danchin, E. G. J.; Bottini, S.
10.1101/2023.07.03.547457 — bioinformatics — Posted on 2023-07-03
4121 Automated system for training and assessing string-pulling behaviors in rodents
Jordan, G. A.; Vishwanath, A.; Holguin, G.; Bartlett, M. J.; Tapia, A. K.; Winter, G. M.; Sexauer, M. M.; Stopera, C. J.; Falk, T.; Cowen, S. L.
10.1101/2023.07.02.547431 — bioengineering — Posted on 2023-07-03
4122 In Vivo Three-dimensional Brain Imaging with Chemiluminescence Probes in Alzheimers Disease Models
Zhang, J.; Wickizer, C.; Ding, W.; Van, R.; Yang, L.; Zhu, B.; Yang, J.; Zhang, C. M.; Shen, S.; Shao, Y.; Ran, C.
10.1101/2023.07.02.547411 — bioengineering — Posted on 2023-07-03
4124 Nanobead-based single-molecule pulldown for single cells
Zhao, Q.; Shen, Y.; Li, X.; Li, Y.; Tian, F.; Yu, X.; Liu, Z.; Tong, R.; Park, H.; Yobas, L.; Huang, P.
10.1101/2023.07.03.546659 — bioengineering — Posted on 2023-07-03
4125 Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats
Ishiwari, K.; King, C. P.; Martin, C. D.; Tripi, J. A.; George, A. M.; Lamparelli, A. C.; Chitre, A.; Polesskaya, O.; Richards, J. B.; Solberg Woods, L. C.; Gancarz, A.; Palmer, A. A.; Dietz, D. M.; Mitchell, S. H.; Meyer, P. J.
10.1101/2023.06.30.547228 — animal behavior and cognition — Posted on 2023-07-03
4126 Identification of State Markers in Anorexia Nervosa: Replication and Extension of Inflammation Associated Biomarkers Using Multiplex Profiling in Anorexia Nervosa and Atypical Anorexia Nervosa
Breithaupt, L.; Holsen, L. M.; Ji, C.; Hu, J.; Petterway, F.; Rosa-Caldwell, M.; Nilsson, I. A. K.; Thomas, J. J.; Williams, K. A.; Boutin, R.; Bulik, C.; Arnold, S. E.; Lawson, E. A.; Misra, M.; Eddy, K. T.
10.1101/2023.06.30.547289 — immunology — Posted on 2023-07-03
4128 BOston Neonatal Brain Injury Dataset for HypoxicIschemic Encephalopathy (BONBID-HIE): Part I. MRI and Manual Lesion Annotation
Bao, R.; Song, Y.; Bates, S. V.; Weiss, R. J.; Foster, A. N.; Cobos, C. J.; Sotardi, S.; Zhang, Y.; Gollub, R. L.; Grant, P. E.; Ou, Y.
10.1101/2023.06.30.546841 — neuroscience — Posted on 2023-07-03
4129 A familial missense variant in the AD gene SORL1 impairs its maturation and endosomal sorting.
Fazeli, E.; Child, D. D.; Bucks, S. A.; Stovarsky, M.; Edwards, G.; Yu, C.-E.; Latimer, C.; Kitago, Y.; Bird, T.; Jayadev, S.; Young, J. E.
10.1101/2023.07.01.547348 — neuroscience — Posted on 2023-07-03
4130 Spinal facilitation of descending motor input
Taccola, G.; Kissane, R.; Culaclii, S.; Apicella, R.; Liu, W.; Gad, P.; Ichiyama, R. M.; Chakrabarty, S.; Edgerton, R.
10.1101/2023.06.30.547229 — neuroscience — Posted on 2023-07-03
4132 Degradation of amyloid beta species by multi-copper oxidases
Yang, J.; Ran, K.; Ma, W.; Chen, L.; Chen, C.; Zhang, C. M.; Ye, H.; Lu, Y. M.; Ran, C.
10.1101/2023.07.02.547398 — neuroscience — Posted on 2023-07-03
4133 RNA-directed DNA Methylation is required for seed development in outbreeding species
Dew-Budd, K. J.; Chow, H. T.; Kendall, T.; David, B. C.; Rozelle, J. A.; Mosher, R. A.; Beilstein, M. A.
10.1101/2023.07.03.547469 — plant biology — Posted on 2023-07-03
4138 Targeting BTN2A1 enhances Vγ9Vδ2 T cell effector functions and triggers tumor cells pyroptosis
le Floch, A. C.; Imbert, C.; Boucherit, N.; Gorvel, L.; Fattori, S.; Orlanducci, F.; Le Roy, A.; Archetti, L.; Crescence, L.; Panicot-Dubois, L.; Dubois, C.; Vey, N.; Briantais, A.; Anastasio, A.; Cano, C.; Guittard, G.; Frechin, M.; Olive, D.
10.1101/2023.06.15.545049 — cancer biology — Posted on 2023-07-03
4139 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seeding experiments
Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.
10.1101/2023.06.25.546428 — biophysics — Posted on 2023-07-03
4140 FuzzyPPI: Human Proteome at Fuzzy Semantic Space
Halder, A. K.; Bandyopadhyay, S. S.; Jedrzejewsk, W.; Basu, S.; Sroka, J.
10.1101/2023.05.24.541959 — bioinformatics — Posted on 2023-07-03
4142 Growth of brown trout in the wild predicted by embryo stress reaction in the laboratory
Bylemans, J.; Marques da Cunha, L.; Wilkins, L. G. E.; Nusbaumer, D.; Uppal, A.; Wedekind, C.
10.1101/2022.07.07.499115 — ecology — Posted on 2023-07-03
4144 Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike
De Cae, S.; Van Molle, I.; van Schie, L.; Shoemaker, S. R.; Deckers, J.; Debeuf, N.; Lameire, S.; Nerinckx, W.; Roose, K.; Fijalkowska, D.; Devos, S.; Desmet, A.-S.; Zavala Marchan, J. C.; Venneman, T.; Ghassabeh, G. H.; Sedeyn, K.; Ballegeer, M.; Vanheerswynghels, M.; De Wolf, C.; Demol, H.; Vanhaverbeke, P.; Lonigro, C.; Bockstal, V.; Rinaldi, M.; Abdelnabi, R.; Neyts, J.; Marqusee, S.; Lambrecht, B. N.; Callewaert, N.; Remaut, H.; Saelens, X.; Schepens, B.
10.1101/2023.03.10.531533 — microbiology — Posted on 2023-07-03
4146 Speech prosody enhances the neural processing of syntax
Degano, G.; Donhauser, P.; Gwilliams, L.; Merlo, P.; Golestani, N.
10.1101/2023.07.03.547482 — neuroscience — Posted on 2023-07-03
4148 A RabGAP-Rab GTPase pair regulates plant autophagy and immunity
Yuen, E. L. H.; Leary, A. Y.; Clavel, M.; Tumtas, Y.; Mohseni, A.; Picchianti, L.; Jamshidiha, M.; Pandey, P.; Duggan, C.; Cota, E.; Dagdas, Y.; Bozkurt, T. O.
10.1101/2023.07.03.547386 — plant biology — Posted on 2023-07-03
4150 The gut microbiome across the cardiovascular risk spectrum
Prins, F. M.; Collij, V.; Groot, H. E.; Björk, J. R.; Swarte, J. C.; Andreu-Sanchez, S.; Jansen, B. H.; Fu, J.; Harmsen, H. J. M.; Zhernakova, A.; Lipsic, E.; Van der Harst, P.; Weersma, R. K.; Gacesa, R.
10.1101/2023.06.28.546971 — genomics — Posted on 2023-07-03
4151 Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy
Yoshinaga, D.; Feng, R.; Prondzynski, M.; Shani, K.; Tharani, Y.; Milosh, J.; Walker, D.; Carreon, K.; Boss, B. M.; Parker, K. K.; Pu, W. T.; Bezzerides, V. J.
10.1101/2023.07.02.546740 — cell biology — Posted on 2023-07-03
4152 Dynamic control of gene expression by ISGF3 and IRF1 duringIFNbeta and IFNgamma signaling
Ravi Sundar Jose Geetha, A.; Fischer, K.; Smesnik, G.; Vogt, A.; Platanitis, E.; Muller, M.; Farlik, M.; Decker, T.
10.1101/2023.06.28.546875 — immunology — Posted on 2023-07-03
4155 Fibroblast growth factor-21 induces skeletal muscle atrophy and increases plasma amino acids in female mice: a potential role for glucocorticoids
Larson, K. R.; Jayakrishnan, D.; Soto Sauza, K.; Goodson, M. L.; Chaffin, A. T.; Davidyan, A.; Pathak, S.; Fang, Y.; Gonzalez Magana, D.; Miller, B. F.; Ryan, K. K.
10.1101/2023.06.27.546599 — physiology — Posted on 2023-07-03
4157 FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancer
Lorito, N.; Subbiani, A.; Smiriglia, A.; Bacci, M.; Bonechi, F.; Tronci, L.; Corrado, A.; Longo, D. L.; Iozzo, M.; Ippolito, L.; Comito, G.; Giannoni, E.; Meattini, I.; Avgustinova, A.; Chiarugi, P.; Bachi, A.; Morandi, A.
10.1101/2023.06.30.547227 — cancer biology — Posted on 2023-07-03
4159 Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods.
Charitakis, N. C.; Salim, A.; Piers, A. T.; Watt, K. I.; Porrello, E. R. C.; Elliott, D. A.; Ramialison, M.
10.1101/2022.10.31.514623 — bioinformatics — Posted on 2023-07-03
4160 A Spatiotemporal Proteomic Map of Human Adipogenesis
Klingelhuber, F.; Frendo-Cumbo, S.; Hmeadi, O.; Taylor, A. J.; Kakimoto, P.; Ribicic, S.; Couchet, M.; Wabitsch, M.; Mueller, T. D.; Ryden, M.; Mejhert, N.; Krahmer, N.
10.1101/2023.07.01.547321 — molecular biology — Posted on 2023-07-03
4165 The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease
Hong, Y.; Zhang, Z.; Yangzom, T.; Chen, A.; Lundberg, B. C.; Fang, E. F.; Sullivan, G. J.; Tzoulis, C.; Bindoff, L. A.; Liang, K. X.
10.1101/2023.07.02.547346 — neuroscience — Posted on 2023-07-02
4166 Genomic context sensitizes regulatory elements to genetic disruption
Ordonez, R.; Zhang, W.; Ellis, G.; Zhu, F.; Ribeiro-dos-Santos, A. M.; Ashe, H. J.; Brosh, R.; Huang, E.; Hogan, M. S.; Boeke, J. D.; Maurano, M. T.
10.1101/2023.07.02.547201 — genomics — Posted on 2023-07-02
4167 Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues.
Kamp, M.; Surmacki, J.; Segarra Mondejar, M.; Young, T.; Chrabaszcz, K.; Joud, F.; Zecchini, V.; Speed, A.; Frezza, C.; Bohndiek, S.
10.1101/2023.07.02.547209 — cell biology — Posted on 2023-07-02
4168 BRD4 directs mitotic cell division by inhibiting DNA damage
Ozato, K.; Wu, T.; Hou, H.; Dey, A.; Bachu, M.; Chen, X.; Wisniewski, J.; Kudoh, F.; Chen, C.; Chauhan, S.; Xiao, H.; Pan, R.
10.1101/2023.07.02.547436 — cell biology — Posted on 2023-07-02
4169 Hippo and Wnt pathways are impaired in Port Wine Birthmark-derived induced pluripotent stem cells and endothelial cells
Nguyen, V.; Gao, C.; Hochman, M.; Kravitz, J.; Chen, E.; Friedman, H.; Wenceslau, C.; Chen, D.; Wang, Y.; Nelson, J. S.; Jegga, A. G.; Tan, W.
10.1101/2023.07.02.547408 — cell biology — Posted on 2023-07-02
4173 Imaging proteins sensitive to direct fusions using transient peptide-peptide interactions
Gidden, Z.; Oi, C.; Johnston, E.; Bhaskar, H.; Rosser, S.; Mochrie, S. G. J.; Horrocks, M. H.; Regan, L.
10.1101/2023.07.01.547312 — biophysics — Posted on 2023-07-02
4174 A Serum- and Feeder-Free System to Generate CD4 and Regulatory T Cells from Human iPSCs
Fong, H.; Mendel, M.; Jascur, J.; Najmi, L.; Kim, K.; Lew, G.; Garimalla, S.; Schock, S.; Hu, J.; Villegas, A.; Conway, A.; Fontenot, J.; Zompi, S.
10.1101/2023.07.01.547333 — cell biology — Posted on 2023-07-02
4176 Uncovering the cis-regulatory program of early human B-cell commitment and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia
Planell, N.; Martinez-de-Morentin, X.; Mouzo, D.; Lara-Astiaso, D.; Vilas-Zornoza, A.; San Martin-Uriz, P.; Alignani, D.; Paiva, B.; Maillo, A.; Kurowska, A.; Urdangarin, A.; Noori, P.; Ortega-Legarreta, A.; Hernaez, M.; Lagani, V.; Kiani, N.; Martin-Subero, J. I.; Ramirez, R. N.; tegner, j. I.; Prosper, F.; Gomez-Cabrero, D.
10.1101/2023.07.01.547234 — immunology — Posted on 2023-07-02
4179 The CB1 Negative Allosteric Modulator PSNCBAM-1 Reduces Ethanol Self-Administration via a Nonspecific Hypophagic Effect
Buechler, H. M.; Sumi, M.; Madhurathakam, I. M.; Donegan, C.; DiGiorgio, F.; Acosta, A.; Uribe, S.; Rahman, M. A.; Sorbello, A.; Fischer, B. D.; Keck, T. M.
10.1101/2023.06.30.547272 — pharmacology and toxicology — Posted on 2023-07-02
4181 Spatial profiling of neuro-immune interactions in gastroenteropancreatic NETs
Duan, S.; Sawyer, T. W.; Witten, B. L.; Song, H.; Else, T.; Merchant, J. L.
10.1101/2023.07.01.547336 — cancer biology — Posted on 2023-07-02
4187 IgG sialylation occurs via the FcRn-mediated recycling pathway in endothelial cells
Glendenning, L. M.; Reynero, K. M.; Kukan, E. N.; Long, M. D.; Cobb, B. A.
10.1101/2023.06.30.547255 — immunology — Posted on 2023-07-02
4190 Toxicogenomic analysis of the carcinogenic potential of plastic additives
Vincoff, S.; Schleupner, B.; Santos, J.; Morrison, M.; Zhang, N.; Dunphy-Daly, M. M.; Eward, W. C.; Armstrong, A. J.; Diana, Z.; Somarelli, J.
10.1101/2023.06.30.547246 — pharmacology and toxicology — Posted on 2023-07-02
4192 Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING-A230 Variants
Tang, Z.; Zhao, J.; Li, Y.; Tomer, S.; Selvaraju, M.; Tien, N.; Sun, D.; Johnson, D. K.; Zhen, A.; Li, P.; Wang, J.
10.1101/2023.07.02.547363 — pharmacology and toxicology — Posted on 2023-07-02
4195 Self-Assembly of a Repeatable DNA Nanohinge System Supporting Higher Order Structure Formation
Law, M.; Sushams, C.; Mackay, D.; Nguyen, S.; Nicholas, R.; Tsai, M. R. G.; Rajkumar, E.; Inaba, F.; Maheden, K.; Abdi, I.; Ho, J. C. H.; Kieft, B.; Hallam, S. J.
10.1101/2023.05.26.542516 — bioengineering — Posted on 2023-07-02
4199 Early resource scarcity causes cortical astrocyte enlargement and sex-specific changes in the orbitofrontal cortex transcriptome in adult rats
Deckers, C.; Karbalaei, R.; Miles, N. A.; Harder, E. V.; Witt, E.; Harris, E. P.; Reissner, K.; Wimmer, M.; Bangasser, D. A.
10.1101/2023.07.01.547315 — neuroscience — Posted on 2023-07-02
4201 The structural-functional neural architectures of implicit and explicit motor learning
Areshenkoff, C. N.; de Brouwer, A. J.; Gale, D. J.; Nashed, J. Y.; Smallwood, J.; Flanagan, J. R.; Gallivan, J. P.
10.1101/2023.07.01.547344 — neuroscience — Posted on 2023-07-02
4202 Labile assembly of a tardigrade protein induces biostasis
Sanchez-Martinez, S.; Nguyen, K.; Biswas, S.; Nicholson, V.; Romanyuk, A. V.; Ramirez, J. F.; KC, S.; Akter, A.; Childs, C.; Usher, E. T.; Ginell, G. M.; Yu, F.; Gollub, E.; Malferrari, M.; Francia, F.; Venturoli, G.; Martin, E. W.; Caporaletti, F.; Giubertoni, G.; Woutersen, S.; Sukenik, S.; Woolfson, D.; Holehouse, A. S.; Boothby, T. C.
10.1101/2023.06.30.547219 — physiology — Posted on 2023-07-02
4203 Targeting CD25-positive lymphoma cells with the antibody-drug conjugate camidanlumab tesirine as single agent or in combination with targeted agents
Spriano, F.; Tarantelli, C.; Cascione, L.; Gaudio, E.; Golino, G.; Scalise, L.; Zucca, E.; Stathis, A.; Van Berkel, P. H.; Zammarchi, F.; Bertoni, F.
10.1101/2023.07.02.547392 — cancer biology — Posted on 2023-07-02
4204 Rapid assessment of changes in phage bioactivity using dynamic light scattering
Dharmaraj, T.; Kratochvil, M. J.; Pourtois, J. D.; Chen, Q.; Hajfathalian, M.; Hargil, A.; Lin, Y.-H.; Evans, Z. R.; Oromi-Bosch, A.; Berry, J. D.; McBride, R.; Haddock, N. L.; Holman, D. R.; Van Belleghem, J. D.; Chang, T. H.; Barr, J. J.; Lavigne, R.; Heilshorn, S. C.; Blankenberg, F. G.; Bollyky, P. L.
10.1101/2023.07.02.547396 — biophysics — Posted on 2023-07-02
4206 Adsorbing DNA to mica by cations: Influence of the valency and ion type
Ibrahim, M.; Wenzel, C.; Lallemang, M.; Balzer, B. N.; Schwierz, N.
10.1101/2023.06.30.547224 — biophysics — Posted on 2023-07-02
4208 New genome scale network modeling and mining workflow for detecting metabolic changes induced by exposure to chemicals
Fresnais, L.; Perin, O.; Riu, A.; Grall, R.; Ott, A.; Fromenty, B.; Gallardo, J. C.; Stingl, M.; Frainay, C.; Jourdan, F.; Poupin, N.
10.1101/2023.06.30.547200 — bioinformatics — Posted on 2023-07-02
4215 ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims
Lewis, T. R.; Makia, M. S.; Castillo, C. M.; Hao, Y.; Al-Ubaidi, M. R.; Skiba, N. P.; Conley, S. M.; Arshavsky, V. Y.; Naash, M. I.
10.1101/2023.07.02.547380 — cell biology — Posted on 2023-07-02
4217 Intra-Articular Sprouting Of Nociceptors Accompanies Progressive Osteoarthritis: Comparative Evidence In Four Murine Models
Obeidat, A. M.; Ishihara, S.; Li, J.; Lammlin, L.; Junginger, L.; Maerz, T.; Miller, R. J.; Miller, R.; Malfait, A.-M.
10.1101/2023.06.30.547216 — neuroscience — Posted on 2023-07-02
4218 Sub-surface deformation of individual fingerprint ridges during tactile interactions
Corniani, G.; Lee, Z. S.; Carre, M. J.; Lewis, R.; Delhaye, B. P.; Saal, H. P.
10.1101/2023.07.02.547395 — neuroscience — Posted on 2023-07-02
4222 Small extracellular vesicles promote stiffness-mediated metastasis
Sneider, A.; Liu, Y.; Starich, B.; Du, W.; Marar, C.; Faqih, N.; Ciotti, G. E.; Kim, J. H.; Krishnan, S.; Ibrahim, S.; Igboko, M.; Locke, A.; Lewis, D. M.; Hong, H.; Karl, M.; Vij, R.; Russo, G. C.; Nair, P. R.; Gomez-de-Mariscal, E.; Habibi, M.; Munoz-Barrutia, A.; Gu, L.; Eisinger-Mathason, T. S. K.; Wirtz, D.
10.1101/2023.07.01.545937 — cancer biology — Posted on 2023-07-02
4223 Homologous mutations in β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation
Liu, C.; Karabina, A.; Meller, A.; Bhattacharjee, A.; Agostino, C. J.; Bowman, G.; Ruppel, K. M.; Spudich, J. A.; Leinwand, L. A.
10.1101/2023.07.02.547385 — biophysics — Posted on 2023-07-02
4226 Configurational entropy is an intrinsic driver of tissue structural heterogeneity
Srivastava, V.; Hu, J. L.; Garbe, J. C.; Veytsman, B.; Shalabi, S. F.; Yllanes, D.; Thomson, M.; LaBarge, M. A.; Huber, G.; Gartner, Z. J.
10.1101/2023.07.01.546933 — bioengineering — Posted on 2023-07-02
4227 The subacromial bursa is a key regulator of the rotator cuff and a new therapeutic target for improving repair
Marshall, B. P.; Ferrer, X. E.; Kunes, J. A.; Innis, A. C.; Luzzi, A. J.; Forrester, L. A.; Burt, K. G.; Lee, A. J.; Song, L.; Hung, C. T.; Levine, W. N.; Kovacevic, D.; Thomopoulos, S.
10.1101/2023.07.01.547347 — bioengineering — Posted on 2023-07-02
4229 Automated escape system: identifying prey's kinematic and behavioral features critical for predator evasion
Sunami, N.; Kimura, H.; Ito, H.; Hashimoto, K.; Sato, Y.; Tachibana, S.; Hidaka, M.; Miyama, K.; Watanabe, H.; Kawabata, Y.
10.1101/2023.07.02.547369 — animal behavior and cognition — Posted on 2023-07-02
4230 Analysis of histone H3K4me3 modifications in bovine placenta derived from different calf-production methods
Hattori, K.; Hoshino, Y.; Kachi, M.; Masuda, Y.; Yamamoto, S.; Honda, S.; Minami, N.; Ikeda, S.
10.1101/2023.07.01.547357 — genomics — Posted on 2023-07-02
4231 Blood prognostic biomarker signatures for hemorrhagic cerebral cavernous malformations (CCMs)
Croft, J.; Grajeda, B.; Abou-Fadel, J.; Ellis, C.; Estevao, I. L.; Almeida, I. C.; Zhang, J.
10.1101/2023.07.01.547354 — genomics — Posted on 2023-07-02
4232 E-PoSa: a novel and effective tool for sampling pollen directly from flowers
Pioltelli, E.; Guzzetti, L.; Tonietti, L.; Copetta, A.; Biella, P.; Campone, L.; Galimberti, A.
10.1101/2023.06.30.547178 — ecology — Posted on 2023-07-02
4235 Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn's disease
Eriksen, C.; Danneskiold-Samsoe, N. B.; Moll, J. M.; Myers, P. N.; Bondegaard, P. W.; Vejrum, S.; Hansen, T. B.; Rosholm, L. B.; Rausch, P.; Allin, K. H.; Jess, T.; Kristiansen, K.; Penders, J.; Jonkers, D. M.; Brix, S.
10.1101/2023.06.30.545711 — immunology — Posted on 2023-07-02
4237 SplicingLore: a web resource for studying the regulation of cassette exons by human splicing factors
Polveche, H.; Valat, J.; Fontrodona, N.; Lapendry, A.; Janczarski, S.; Mortreux, F.; Auboeuf, D.; Bourgeois, C. F.
10.1101/2023.06.30.547181 — genomics — Posted on 2023-07-02
4238 Avifaunal Species diversity from Southern West part of West Bengal, India
Dinda, S. C.; Pal, A.; Khanra, A.; Sarkar, M.; Mandal, B.; Das, P. C.; Mondal, N.
10.1101/2023.06.30.547191 — ecology — Posted on 2023-07-02
4239 3D reconstructions of parasite development and the intracellular niche of the microsporidian pathogen E. intestinalis
Antao, N. V.; Lam, C.; Davydov, A.; Riggi, M.; Sall, J.; Petzold, C.; Liang, F.-X.; Iwasa, J.; Ekiert, D. C.; Bhabha, G.
10.1101/2023.07.02.547383 — microbiology — Posted on 2023-07-02
4240 In vivo magnetic recording of single-neuron action potentials
Klein, F. J.; Jendritza, P.; Chopin, C.; Parto-Dezfouli, M.; Solignac, A.; Fermon, C.; Pannetier-Lecoeur, M.; Fries, P.
10.1101/2023.06.30.547194 — neuroscience — Posted on 2023-07-02
4242 Objective QC for diffusion MRI data: artefact detection using normative modelling
Cirstian, R.; Forde, N.; Sotiropoulos, S.; Andersson, J.; Beckmann, C.; Marquand, A.
10.1101/2023.06.30.546837 — neuroscience — Posted on 2023-07-02
4243 Uncovering novel roles of miR-122 in the pathophysiology of the liver: Potential interaction with NRF1 and E2F4 signaling
Paluschinski, M.; Schira-Heinen, J.; Pellegrino, R.; Heij, L. R.; Bednarsch, J.; Neumann, U. P.; Longerich, T.; Stuehler, K.; Luedde, T.; Castoldi, M.
10.1101/2023.06.30.547158 — cancer biology — Posted on 2023-07-02
4244 Differential modulation of miR-122 transcription by TGFbeta1/BMP6: implications for nonresolving inflammation and hepatocarcinogenesis
Paluschinski, M.; Kordes, C.; Vucur, M.; Buettner, V.; Xu, H. C.; Shinde, P.; Lang, P. A.; Luedde, T.; Castoldi, M.
10.1101/2023.06.30.547174 — cancer biology — Posted on 2023-07-02
4249 BeeDC: An R package and globally synthesised and flagged bee occurrence dataset
Dorey, J. B.; Fischer, E. E.; Chesshire, P. R.; Nava-Bolanos, A.; OReilly, R. L.; Bossert, S.; Collins, S. M.; Lichtenberg, E. M.; Tucker, E. M.; Smith-Pardo, A.; Falcon-Brindis, A.; Guevara, D. A.; Ribeiro, B.; de Pedro, D.; Pickering, J.; James, K.-L.; Parys, K. A.; McCabe, L. M.; Rogan, M. S.; Minckley, R. L.; Velazco, S. J. E.; Griswold, T.; Zarrillo, T. A.; Jetz, W.; Sica, Y. V.; Orr, M. C.; Guzman, L. M.; Ascher, J. A.; Hughes, A. C.; Cobb, N. S.
10.1101/2023.06.30.547152 — ecology — Posted on 2023-07-02
4250 An automated approach for systematic detection of Key Biodiversity Areas
Nania, D.; Ficetola, G. F.; Falaschi, M.; Pacifici, M.; Lumbierres, M.; Rondinini, C.
10.1101/2023.06.30.547173 — ecology — Posted on 2023-07-02
4253 Shape-changing electrode array for minimally invasive large-scale intracranial brain activity mapping
Wei, S.; Jiang, A.; Sun, H.; Zhu, J.; Liu, X.; Xu, Z.; Zhang, J.; Jia, S.; Shang, Y.; Fu, X.; Li, G.; Wang, P.; Xia, Z.; Jiang, T.; Cao, A.; Duan, X.
10.1101/2023.06.29.547140 — neuroscience — Posted on 2023-07-02
4261 A bistable inhibitory OptoGPCR for multiplexed optogenetic control of neural circuits
Wietek, J.; Nozownik, A.; Pulin, M.; Saraf-Sinik, I.; Matosevich, N.; Malan, D.; Brown, B. J.; Dine, J.; Levy, R.; Litvin, A.; Regev, N.; Subramaniam, S.; Bitton, E.; Benjamin, A.; Copits, B. A.; Sasse, P.; Rost, B. R.; Schmitz, D.; Soba, P.; Nir, Y.; Wiegert, J. S.; Yizhar, O.
10.1101/2023.07.01.547328 — neuroscience — Posted on 2023-07-02
4264 TrkB-dependent regulation of molecular signaling across septal cell types
Rodriguez, L. A.; Tran, M. N.; Garcia-Flores, R.; Pattie, E. A.; Kim, S.-H.; Shin, J. H.; Lee, Y. K.; Divecha, H. R.; Montoya, C.; Jaffe, A. E.; Torres, L. C.; Page, S. C.; Martinowich, K.
10.1101/2023.06.29.547069 — neuroscience — Posted on 2023-07-01
4265 ISiCell: involving biologists in the design process of agent-based models in cell biology
Cogoni, F.; Bernard, D.; Kazhen, R.; Valitutti, S.; Lobjois, V.; Cussat-Blanc, S.
10.1101/2023.06.30.547165 — systems biology — Posted on 2023-07-01
4266 Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib
Pang, Y.; Yu, G.; Sergi, Z.; Li, Q.; Sang, X.; Kim, O.; Wang, H.; Ranjan, A.; Merchant, M.; Oudit, B.; Robey, R. W.; Soheilian, F.; Tran, B.; Nunez, F. J.; Zhang, M.; Song, H.; Zhang, W.; Davis, D.; Gilbert, M. R.; Gottesman, M. M.; Liu, Z.; Khan, J.; Thomas, C. J.; Castro, M. G.; Wu, J.
10.1101/2023.06.29.547143 — cancer biology — Posted on 2023-07-01
4267 XPA tumor variants lead to defects in NER that sensitize cells to cisplatin
Blee, A. M.; Gallagher, K. S.; Kim, H.-S.; Kim, M.; Troll, C. R.; D'Souza, A.; Park, J.; Neufer, P. D.; Schärer, O. D.; Chazin, W. J.
10.1101/2023.06.29.547124 — cancer biology — Posted on 2023-07-01
4270 Single Cell Multi-Omics of an iPSC Model of Human Sinoatrial Node Development Reveals Genetic Determinants of Heart Rate and Arrhythmia Susceptibility
Engel, J. L.; Zhang, X.; Lu, D. R.; Vila, O. F.; Arias, V.; Lee, J.; Hale, C.; Hsu, Y.-H.; Li, C.-M. K.; Vedantham, V.; Ang, Y.-S.
10.1101/2023.07.01.547335 — developmental biology — Posted on 2023-07-01
4272 Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation
Wu, D.; Zhang, X.; Zimmerly, K.; Wang, R.; Livingston, A.; Wu, X.; Mandell, M.; Liu, M.; Yang, X. A.
10.1101/2023.06.30.547286 — immunology — Posted on 2023-07-01
4274 Unbiased phosphoproteomics analysis unveils modulation of insulin signaling by extramitotic CDK1 kinase activity in human myotubes
Han, B.; Li, G. X.; Liew, W. L.; Chan, E.; Huang, S.; Khoo, C. M.; Leow, M. K.-S.; Lee, Y. S.; Zhao, T.; Wang, L. C.; Sobota, R. M.; Choi, H.; Liu, M. H.; Kim, K. P.; Tai, E. S.
10.1101/2023.06.30.547176 — physiology — Posted on 2023-07-01
4276 RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential.
Van Espen, B.; Oo, H. Z.; Collins, C.; Fazil, L.; Molinolo, A.; Murad, R.; Gleave, M.; Ronai, Z. A.
10.1101/2023.06.29.547118 — cancer biology — Posted on 2023-07-01
4281 Topology-dependent DNA binding
Kolbeck, P. J.; Tisma, M.; Analikwu, B. T.; Vanderlinden, W.; Dekker, C.; Lipfert, J.
10.1101/2023.06.30.547266 — biophysics — Posted on 2023-07-01
4283 A sensor complements the steric gate when DNA polymerase ϵ discriminates ribonucleotides.
Parkash, V.; Kulkarni, Y.; Bylund, G.; Osterman, P.; Kamerlin, S. C. L.; Johansson, E.
10.1101/2023.07.01.547322 — biochemistry — Posted on 2023-07-01
4284 A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction
Walker, M. F.; Zhang, J.; Steiner, W.; Ku, P.-I.; Zhu, J.-F.; Michaelson, Z.; Yen, Y.-C.; Long, A. B.; Casey, M. J.; Poddar, A.; Nelson, I. B.; Arveseth, C. D.; Nagel, F.; Clough, R.; LaPotin, S.; Kwan, K. M.; Schulz, S.; Stewart, R. A.; Tesmer, J. J. G.; Caspary, T.; Subramanian, R.; Ge, X.; Myers, B. R.
10.1101/2023.05.10.540226 — cell biology — Posted on 2023-07-01
4285 Global biochemical analysis reveals miRNA-RNA virus and miRNA-enhancer targets regulating immune signalling in Respiratory syncytial virus infection
Ressel, S.; Kumar, S.; Bermudez-Barrientos, J. R.; Gordon, K.; Lane, J.; Wu, J.; Abreu-Goodger, C.; Schwarze, J.; Buck, A. H.
10.1101/2023.06.05.543706 — molecular biology — Posted on 2023-07-01
4286 A Spatiotemporal Proteomic Map of Human Adipogenesis
Krahmer, N.; Klingelhuber, F.; Frendo-Cumbo, S.; Hmeadi, O.; Taylor, A. J.; Kakimoto, P.; Ribicic, S.; Wabitsch, M.; Mueller, T. D.; Ryden, M.; Mejhert, N.; Couchet, M.
10.1101/2023.07.01.547321 — molecular biology — Posted on 2023-07-01
4289 Locus coeruleus neuromelanin predicts ease of attaining and maintaining neural states of high attentiveness
Hussain, S.; Menchaca, I.; Shalchy, M. A.; Yaghoubi, K.; langley, j.; Seitz, A.; Hu, X.; Peters, M. A. K.
10.1101/2022.03.07.483289 — neuroscience — Posted on 2023-07-01
4292 Computational repurposing of oncology drugs through off-target drug binding interactions from pharmacological databases
Walpole, I. R.; Zaman, F. Y.; Zhao, P.; Marshall, V. M.; Lin, F. P.; Thomas, D. M.; Shackleton, M.; Antolin, A. A.; Ameratunga, M.
10.1101/2023.07.01.547311 — biochemistry — Posted on 2023-07-01
4293 COVID-related anthropause highlights the impact of marine traffic on breeding little penguins
Dupuis, B.; Kato, A.; Joly, N.; Saraux, C.; Ropert-Coudert, Y.; Chiaradia, A.; Chimienti, M.
10.1101/2023.06.30.547199 — ecology — Posted on 2023-07-01
4296 TrkB-dependent regulation of molecular signaling across septal cell types
Rodriguez, L. A.; Tran, M. N.; Garcia-Flores, R.; Pattie, E. A.; Kim, S.-H.; Shin, J. H.; Lee, Y. K.; Divecha, H. R.; Montoya, C.; Jaffe, A. E.; Torres, L. C.; Page, S. C.; Martinowich, K. C.
10.1101/2023.06.29.547069 — neuroscience — Posted on 2023-07-01
4297 Disentangling gene expression burden identifies generalizable phenotypes induced by synthetic gene networks
Hasnain, A.; Borujeni, A. E.; Park, Y.; Becker, D.; Maschhoff, P.; Urrutia, J.; Rydell, L.; Balakrishnan, S.; Dorfan, Y.; Voigt, C.; Yeung, E.
10.1101/2023.06.29.547078 — systems biology — Posted on 2023-07-01
4299 Diagnosis of planktonic trophic network dynamics with sharp qualitative changes
Gaucherel, C.; Fayolle, S.; Savelli, R.; Philippine, O.; Pommereau, F.; Dupuy, C.
10.1101/2023.06.29.547055 — ecology — Posted on 2023-07-01
4300 Geometric Epitope and Paratope Prediction
Pegoraro, M.; Domine, C.; Rodola, E.; Velickovic, P.; Deac, A.
10.1101/2023.06.29.546973 — immunology — Posted on 2023-07-01
4301 Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice.
Scott, K. A.; Tan, Y.; Johnson, D. N.; El Saafien, K.; Baumer-Harrison, C.; Eikenberry, S. A.; Sa, J. M.; de Lartigue, G.; de Kloet, A. D.; Krause, E. G.
10.1101/2023.06.29.547073 — neuroscience — Posted on 2023-07-01
4303 Intrinsic motor network connectivity predicts corticospinal excitability
Marzetti, L.; Basti, A.; Baldassarre, A.; Guidotti, R.; Metsomaa, J.; Zrenner, C.; D'Andrea, A.; Makkinayeri, S.; Pieramico, G.; Ilmoniemi, R. J.; Ziemann, U.; Romani, G. L.; Pizzella, V.
10.1101/2023.06.29.547027 — neuroscience — Posted on 2023-07-01
4304 Microvascular plasticity in stroke recovery: Longitudinal snapshots, network statistical analysis, and dynamics
Mihelic, S. A.; Engelmann, S. A.; Sadr, M. S.; Jafari, C. Z.; Zhou, A.; Williamson, M. R.; Dunn, A. K.
10.1101/2023.06.29.547081 — neuroscience — Posted on 2023-07-01
4306 Design, construction and optimization of formaldehyde growth biosensors with broad application in Biotechnology
Schann, K.; Bakker, J.; Boinot, M.; Kuschel, P.; He, H.; Nattermann, M.; Erb, T.; Bar-Even, A.; Wenk, S.
10.1101/2023.06.29.547045 — bioengineering — Posted on 2023-07-01
4307 Competitive Amplification Networks enable molecular pattern recognition with PCR
Goertz, J. P.; Sedgwick, R.; Smith, F.; Kaforou, M. P.; Wright, V. J.; Herberg, J. A.; Kote-Jarai, Z.; Eeles, R.; Levin, M.; Misener, R.; van der Wilk, M.; Stevens, M. M.
10.1101/2023.06.29.546934 — bioengineering — Posted on 2023-07-01
4308 Behavioral and Neural Resilience to Isolation in a Eusocial Insect
Goolsby, B. C.; Smith, E. J.; Muratore, I. B.; Coto, Z. N.; Muscedere, M. L.; Traniello, J. F. A.
10.1101/2023.06.29.546928 — animal behavior and cognition — Posted on 2023-07-01
4309 Molecular quantitative trait loci in reproductive tissues impact male fertility in a large mammal
Mapel, X. M.; Kadri, N. K.; Leonard, A. S.; He, Q.; Lloret-Villas, A.; Bhati, M.; Hiltpold, M.; Pausch, H.
10.1101/2023.06.29.547066 — genomics — Posted on 2023-07-01
4311 Revisiting the role of mean annual precipitation in shaping functional trait distributions at a continental scale
Towers, I. R.; Vesk, P. A.; Wenk, E.; Gallagher, R. V.; Windecker, S.; Wright, I. J.; Falster, D.
10.1101/2023.06.29.546983 — ecology — Posted on 2023-07-01
4312 Structural insights into dual-antagonize mechanism of AB928 on adenosine A2 receptors
Weng, Y.; Yang, X.; Zhang, Q.; Chen, Y.; Xu, Y.; Zhu, C.; Xie, Q.; Wang, Y.; Yang, H.; Liu, M.; Lu, W.; Song, G.
10.1101/2023.07.01.547314 — cell biology — Posted on 2023-07-01
4313 Engagement of sialylated glycans with Siglec receptors on myeloid suppressor cells inhibit anti-cancer immunity via CCL2
Wieboldt, R.; Carlini, E.; Chia-wei, L.; Boersch, A.; Zingg, A.; Lardinois, D.; Herzig, P.; Don, L.; Zippelius, A.; Laeubli, H.; Rodrigues Mantuano, N.
10.1101/2023.06.29.547025 — immunology — Posted on 2023-07-01
4315 Integrative analysis of CAKUT multi-omics data
Bayjanov, J. R.; Doornbos, C.; Ozisik, O.; Shin, W.; Queralt-Rosinach, N.; Wijnbergen, D.; Saulnier Blache, J.-S.; Schanstra, J. P.; Fernandez, J. M.; Kaliyaperumal, R.; Baudot, A.; t Hoen, P. A. C.; Ehrhart, F.
10.1101/2023.06.29.547015 — systems biology — Posted on 2023-07-01
4316 Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations
Hanson, A.; McClenaghan, C.; Weng, K.-C.; Colijn, S.; Stratman, A. N.; Halabi, C. M.; Grange, D. K.; Silva, J. R.; Nichols, C. G.
10.1101/2023.06.29.547088 — physiology — Posted on 2023-07-01
4319 Maternal adaptations in mouse lactation are vulnerable to diet-induced excess adiposity
Breznik, J. A.; Ribeiro, T. A.; Yeo, E.; Kennelly, B. K.; Wang, X.; Quin, C.; Cowbrough, B.; Verdu, E. F.; Bowdish, D. M. E.; Sloboda, D. M.
10.1101/2023.06.30.547298 — developmental biology — Posted on 2023-07-01
4321 Loss of NR2E3 disrupts rod photoreceptor cell maturation causing a fate switch late in human retinal development.
Mullin, N. K.; Bohrer, L. R.; Voigt, A. P.; Wright, A.; Lozano, L. P.; Mullins, R. F.; Stone, E. M.; Tucker, B. A.
10.1101/2023.06.30.547279 — developmental biology — Posted on 2023-07-01
4326 A Cardiac Transcriptional Enhancer is Repurposed During Regeneration to Activate an Anti-proliferative Program
Panten, J.; Lubertozzi, A.; Russell, A.; Segura-Bermudez, J.; Franz, C.; Zevallos, M.; Pietrzak, M.; Poss, K. D.; Goldman, J. A.
10.1101/2023.06.30.547239 — developmental biology — Posted on 2023-07-01
4328 Epiboly in zebrafish requires the coordinated activity of NADPH oxidases and dynamin.
Mendez-Cruz, F. J.; Ramirez-Corona, A.; Reza-Medina, B.; Mendieta-Serrano, M. A.; Schnabel, D.; Lomeli, H.; Salas-Vidal, E.
10.1101/2023.06.30.547135 — developmental biology — Posted on 2023-07-01
4329 Fetal daily rhythms develop during pregnancy and entrain to the maternal circadian system
Bates, K.; Sapiro, E.; Amme, J. L.; McCarthy, R.; Nikhil, K. L.; Speck, S.; Vasireddy, V.; Roberts, E.; Martin-Fairey, C.; Dominguez-Romero, M.-E.; Garcia Cardenas, S. P.; England, S. K.; Herzog, E. D.
10.1101/2023.06.30.547166 — developmental biology — Posted on 2023-07-01
4330 Wnt signaling couples G2 phase control with differentiation during hematopoiesis
Goins, L. M.; Girard, J. R.; Mondal, B. C.; Buran, S.; Su, C. C.; Tang, R.; Biswas, T.; Banerjee, U.
10.1101/2023.06.29.547151 — developmental biology — Posted on 2023-07-01
4333 The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies
Liou, R. H.-C.; Chen, S.-W.; Cheng, H.-C.; Wu, P.-C.; Chang, Y.-F.; Wang, A.-G.; Fann, M.-J.; Wong, Y.-H.
10.1101/2023.07.01.547305 — cell biology — Posted on 2023-07-01
4336 Easing OMERO adoption with ezomero
Martins Ratamero, E.; Govek, K.; Mateos Langerak, J.; Cervantes Sanchez, F.; Mellert, D. J.
10.1101/2023.06.29.546930 — bioinformatics — Posted on 2023-07-01
4339 Cranes soar on thermal updrafts behind cold fronts as they migrate across the sea
Pekarsky, S.; Shohami, D.; Horvitz, N.; Bowie, R. C. K.; Kamath, P.; Markin, Y.; Getz, W.; Nathan, R.
10.1101/2023.06.29.547013 — ecology — Posted on 2023-07-01
4340 Human Th17- and IgG3-associated autoimmunity induced by a translocating gut pathobiont
Gronke, K.; Nguyen, M.; Santamaria de Souza, N.; Schumacher, J.; Yang, Y.; Sonnert, N. D.; Leopold, S.; Martin, A.; Hallet, R.; Richter, K.; Schubert, D.; Daniel, G. M.; Dylus, D.; Forkel, M.; Manfredo Vieira, S.; Schwinge, D.; Schramm, C.; Lassen, K. G.; Piali, L.; Palm, N. W.; Bieniossek, C.; Kriegel, M. A.
10.1101/2023.06.29.546430 — immunology — Posted on 2023-07-01
4341 An ex vivo human model for safety assessment of immunotoxicity of engineered nanomaterials
Blersch, J.; Kurkowsky, B.; Meyer-Berhorn, A.; Grabowska, A. K.; Feidt, E.; Junglas, E.; Roth, W.; Stappert, D.; Kuebelbeck, A.; Denner, P.; Fava, E.
10.1101/2023.06.29.547008 — immunology — Posted on 2023-07-01
4342 Interferons are the key cytokines acting on pancreatic islets in type 1 diabetes
Coomans de Brachene, A.; Alvelos, M. I.; Szymczak, F.; Zimath, P. L.; Castela, A.; Marmontel de Souza, B.; Roca Rivada, A.; Marin-Canas, S.; Yi, X.; Op de Beeck, A.; Morgan, N. G.; Sonntag, S.; Jawurek, S.; Title, A. C.; Yesildag, B.; Pattou, F.; Kerr-Conte, J.; Montanya, E.; Nacher, M.; Marselli, L.; Marchetti, P.; Richardson, S. J.; Eizirik, D. L.
10.1101/2023.06.29.547000 — immunology — Posted on 2023-07-01
4343 Applying high-resolution spatial transcriptomics to characterise the amyloid plaque cell niche in Alzheimer's Disease
Mallach, A.; Zielonka, M.; van Lieshout, V.; An, Y.; Khoo, J. H.; Vanheusden, M.; Chen, W.-T.; Moechars, D.; Arancibia-Carcamo, I. L.; Fiers, M.; De Strooper, B.
10.1101/2023.06.29.546675 — neuroscience — Posted on 2023-07-01
4346 Single-nucleus analysis characterizes non-enhancing region of recurrent high-grade glioma
Patel, K. S.; Tessema, K. K.; Kawaguchi, R.; Alvarado, A. G.; Muthukrishnan, S. D. D.; Hagiwara, A.; Swarup, V.; Liau, L. M.; Wang, A. C.; Yong, W.; Geschwind, D.; Nakano, I.; Goldman, S.; Everson, R.; Ellingson, B.; Kornblum, H.
10.1101/2022.10.10.511639 — neuroscience — Posted on 2023-07-01
4351 CLARUS: An Interactive Explainable AI Platform for Manual Counterfactuals in Graph Neural Networks
Beinecke, J. M.; Saranti, A.; Angerschmid, A.; Pfeifer, B.; Klemt, V.; Holzinger, A.; Hauschild, A.-C.
10.1101/2022.11.21.517358 — bioinformatics — Posted on 2023-07-01
4352 Genome-wide analysis of promoter contacts identifies novel regulators of late-stage adipogenesis
Sandovici, I.; Mifsud, B.; Emery, A.; Gulati, P.; Kentistou, K. A.; Banu, A.; Campbell, N.; Hardwick, B. S.; Crooks, A. T.; Fernandez-Twinn, D. S.; Mennitti, L. V.; Srour, L.; Awad, S.; Chiarugi, D.; Hamilton, R. H.; Wingett, S. W.; Fraser, P.; Ong, K. K.; Schoenfelder, S.; Mohammad, F.; O'Rahilly, S.; Perry, J. R. B.; Venkitaraman, A. R.; E. Ozanne, S.; Constancia, M.
10.1101/2023.06.27.546683 — genetics — Posted on 2023-07-01
4355 MIDAS: a deep generative model for mosaic integration and knowledge transfer of single-cell multimodal data
He, Z.; Chen, Y.; Hu, S.; An, S.; Shi, J.; Liu, R.; Zhou, J.; Dong, G.; Shi, J.; Zhao, J.; Wang, J.; Zhu, Y.; Ou-Yang, L.; Bo, X.; Ying, X.
10.1101/2022.12.13.520262 — bioinformatics — Posted on 2023-07-01
4356 Organisms use mode-switching to solve the explore-vs-exploit problem
Biswas, D.; Lamperski, A.; Yang, Y.; Hoffman, K.; Guckenheimer, J.; Fortune, E. S.; Cowan, N. J.
10.1101/2023.01.11.523566 — animal behavior and cognition — Posted on 2023-07-01