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Archive, 2021-10

3 Targeted intragenic demethylation initiates chromatin rewiring for gene activation
Liu, Y. V.; Bassal, M. A.; Jayasinghe, M. K.; Lin, Q. X. X.; Wu, C. S.; Tang, J. P.; Kwon, J.; Zhou, Q.; Tan, H. K.; Ebralidze, A. K.; Le, M. T. N.; Chai, L.; Benoukraf, T.; Di Ruscio, A.; Tenen, D. G.
10.1101/2020.07.16.205922 — genetics — Posted on 2021-10-31
8 Characterization of γ-Glutamyl Peptidases and γ-Glutamyl Cyclotransferases for Glutathione Degradation in Arabidopsis
Ito, T.; Kitaiwa, T.; Nishizono, K.; Umahashi, M.; Miyaji, S.; Agake, S.-i.; Kuwahara, K.; Yokoyama, T.; Maruyama-Nakashita, A.; Sugiyama, R.; Yokota Hirai, M.; Ohkama-Ohtsu, N.
10.1101/2021.10.29.466391 — plant biology — Posted on 2021-10-31
11 MFN2 Influences Amyotrophic Lateral Sclerosis Pathology
Russell, K.; Downie, J. M.; Gibson, S.; Figueroa, P.; Steely, C. J.; Bromberg, M.; Murtaugh, L. C.; Jorde, L. B.; Pulst, S. M.
10.1101/2021.10.30.466517 — genetics — Posted on 2021-10-31
17 Electronic Mapping of a Bacterial Genome with Dual Solid-State Nanopores and Active Single-Molecule Control
Rand, A.; Zimny, P.; Nagel, R.; Telang, C.; Mollison, J.; Bruns, A.; Leff, E.; Reisner, W.; Dunbar, W. B.
10.1101/2021.10.29.466509 — biophysics — Posted on 2021-10-31
19 Genotyping of structural variation using PacBio high-fidelity sequencing
Zhang, Z.; Zhang, J.; Kang, L.; Qiu, X.; Niu, B.; Bi, A.; Zhao, X.; Xu, D.; Wang, J.; Yin, C.; Fu, X.; Lu, F.
10.1101/2021.10.28.466362 — bioinformatics — Posted on 2021-10-31
20 Extracellular Vesicles Deliver Mitochondria and HSP27 Protein to Protect the Blood-Brain Barrier
Dave, K.; Reynolds, M. J.; Stolz, D. B.; Babidhan, R.; Dobbins, D. X.; Yankello, H.; Reddy, R.; Bae, Y.; Shiva, S.; Soundara Manickam, D.
10.1101/2021.10.29.466491 — bioengineering — Posted on 2021-10-31
23 Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines
Benaglio, P.; Zhu, H.; Okino, M.-L.; Yan, J.; Elgamal, R.; Nariai, N.; Beebe, E.; Korgaonkar, K.; Qiu, Y.; Donovan, M.; Chiou, J.; Newsome, J.; Kaur, J.; Corban, S.; Aylward, A.; Taipale, J.; Ren, B.; Frazer, K. A.; Sander, M.; Gaulton, K. J.
10.1101/2021.10.29.466025 — genomics — Posted on 2021-10-31
25 A macromutation eliminates colour patterning in captive butterflies
Hanly, J. J.; Livraghi, L.; Heryanto, C.; McMillan, W. O.; Jiggins, C. D.; Gilbert, L. E.; Martin, A.
10.1101/2021.10.29.466422 — genetics — Posted on 2021-10-31
27 The colonial legacy of herbaria
Park, D. S.; Feng, X.; Akiyama, S.; Ardiyani, M.; Avendano, N.; Barina, Z.; Bartschi, B.; Belgrano, M.; Betancur, J.; Bijmoer, R.; Bogaerts, A.; Cano, A.; Danihelka, J.; Garg, A.; Giblin, D. E. E.; Gogoi, R.; Guggisberg, A.; Hyvarinen, M.; James, S. A.; Sebola, R. J.; Katagiri, T.; Kennedy, J. A.; Komil, T. S.; Lee, B.; Lee, S. M. L.; Magri, D.; Marcucci, R.; Masinde, S.; Melnikov, D.; Mraz, P.; Mulenko, W.; Musili, P.; Mwachala, G.; Nelson, B. E.; Niezgoda, C.; Novoa, C.; Orli, S.; Paton, A.; Payette, S.; Perkins, K. D.; Ponce, M.; Rainer, H.; Rasingam, L.; Rustiami, H.; Shiyan, N. M.; Slette
10.1101/2021.10.27.466174 — ecology — Posted on 2021-10-31
29 Development and evaluation of PCR primers for environmental DNA (eDNA) metabarcoding of Amphibia
Sakata, M. K.; Kawata, M. U.; Kurabayashi, A.; Kurita, T.; Nakamura, M.; Shirako, T.; kakehashi, R.; Nishikawa, K.; Hossman, M. Y.; Nishijima, T.; Kabamoto, J.; Miya, M.; Minamoto, T.
10.1101/2021.10.29.466374 — ecology — Posted on 2021-10-31
31 Identification and tracking of alloreactive T cell clones in Rhesus Macaques through the RM-scTCR-Seq platform.
Gerdemann, U.; Fleming, R. A.; Kaminski, J.; McGuckin, C.; Rui, X.; Lane, J. F.; Keskula, P.; Cagnin, L.; Shalek, A. K.; Tkachev, V.; Kean, L. S.
10.1101/2021.10.29.466482 — immunology — Posted on 2021-10-31
32 Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity
Jerby, L.; Tooley, K.; Escobar, G.; Dandekar, G.; Madi, A.; Goldschmidt, E.; Lambden, C.; Rozenblatt-Rosen, O.; Anderson, A. C.; Regev, A.
10.1101/2021.10.31.466532 — immunology — Posted on 2021-10-31
37 SETD2 negatively regulates cell size through its catalytic activity and SRI domain
Molenaar, T. M.; Kwesi-Maliepaard, E. M.; Silva, J.; Malik, M.; Faller, W. J.; van Leeuwen, F.
10.1101/2021.10.31.465891 — cell biology — Posted on 2021-10-31
38 Chlamydomonas ARMC2/PF27 is an obligate cargo adapter for IFT of radial spokes
Lechtreck, K. F.; Liu, Y.; Dai, J.; Alkhofash, R.; Butler, J.; Alford, L.; Yang, P.
10.1101/2021.10.31.466660 — cell biology — Posted on 2021-10-31
42 Molecular mechanism of Arp2/3 complex inhibition by Arpin
Fregoso, F. E.; van Eeuwen, T.; Simanov, G.; Rebowski, G.; Boczkowska, M.; Zimmet, A.; Gautreau, A. M.; Dominguez, R.
10.1101/2021.10.30.466598 — biochemistry — Posted on 2021-10-31
51 A comprehensive evaluation of CRISPR lineage recorders using TraceQC
Hu, J.; Jeong, H.-H.; Al-Ouran, R.; Bado, I.; Zhang, W.; Zhang, X.; Liu, Z.
10.1101/2021.10.29.466515 — bioinformatics — Posted on 2021-10-30
56 Promoter sequence and architecture determine expression variability and confer robustness to genetic variants
Einarsson, H.; Salvatore, M.; Vaagenso, C.; Alcaraz, N.; Bornholdt Lange, J.; Rennie, S.; Andersson, R.
10.1101/2021.10.29.466407 — genomics — Posted on 2021-10-30
58 CTCF blocks anti-sense transcription initiation at divergent gene promoters
Luan, J.; Syrett, C. M.; Vermunt, M. W.; Cote, A.; Tome, J. M.; Zhang, H.; Huang, A.; Luppino, J. M.; Keller, C. A.; Giardine, B. M.; Zhang, S.; Dunagin, M. C.; Zhang, Z.; Joyce, E. F.; Lis, J. T.; Raj, A.; Hardison, R. C.; Blobel, G. A.
10.1101/2021.10.30.465508 — molecular biology — Posted on 2021-10-30
60 Identification, Characterization and Synthesis of Natural Parasitic Cysteine Protease Inhibitors -- More Potent Falcitidin Analogs
Brinkmann, S.; Semmler, S.; Kersten, C.; Patras, M. A.; Kurz, M.; Fuchs, N.; Hammerschmidt, S. J.; Legac, J.; Hammann, P. E.; Vilcinskas, A.; Rosenthal, P. J.; Schirmeister, T.; Bauer, A.; Schaeberle, T. F.
10.1101/2021.10.30.466580 — microbiology — Posted on 2021-10-30
62 Natural transformation protein ComFA exhibits single-stranded DNA translocase activity
Foster, H. R.; Lin, X.; Srikant, S.; Cueny, R. R.; Falbel, T. G.; Keck, J. L.; Gaudet, R.; Burton, B. M.
10.1101/2021.10.29.466550 — microbiology — Posted on 2021-10-30
63 Genotype-Phenotype Correlation of T Cell Subtypes Reveals Senescent and Cytotoxic Genes in Alzheimer's Disease
Dressman, D.; Buttrick, T.; Cimpean, M.; Bennett, D.; Menon, V.; Bradshaw, E. M.; Vardarajan, B.; Elyaman, W.
10.1101/2021.10.19.464914 — immunology — Posted on 2021-10-30
65 Estimating the Inter- and Intra-Rater Reliability for NASH Fibrosis Staging in the Presence of Bridge Ordinal Ratings with Hierarchical Bridge Category Models
Levy, J.; Bobak, C.; Azizgolshani, N.; Liu, X.; Ren, B.; Lisovsky, M.; Suriawinata, A.; Christensen, B.; O'Malley, J.; Vaickus, L.
10.1101/2021.10.27.466144 — pathology — Posted on 2021-10-30
66 Proteins mediating different DNA topologies block RNAP elongation with different efficiency
Lu, Y.; Borjas, G.; Voros, Z.; Hendrickson, C.; Shearwin, K. E.; Dunlap, D.; Finzi, L.
10.1101/2021.10.29.466366 — biophysics — Posted on 2021-10-30
68 Effect of G4C2-Repeat Expansions on the Motion of Lysosomes Inside Neurites.
Mytiliniou, M.; Wondergem, J. A. J.; Feliksik, M.; Schmidt, T.; Heinrich, D.
10.1101/2021.10.29.466472 — biophysics — Posted on 2021-10-30
71 A hold-and-feed mechanism drives directional DNA loop extrusion by condensin
Shaltiel, I. A.; Datta, S.; Lecomte, L.; Hassler, M.; Kschonsak, M.; Bravo, S.; Stober, C.; Eustermann, S.; Haering, C. H.
10.1101/2021.10.29.466147 — biochemistry — Posted on 2021-10-30
72 Illumina But With Nanopore: Sequencing Illumina libraries at high accuracy on the ONT MinION using R2C2
Zee, A.; Deng, D. Z. Q.; Adams, M.; Schimke, K. D.; Corbett-Detig, R.; Russell, S. L.; Zhang, X.; Schmitz, R. J.; Vollmers, C.
10.1101/2021.10.30.466545 — genomics — Posted on 2021-10-30
73 Plasmodium DDI1 is an essential chromatin-associated protein with a role in DNA-protein crosslink repair
Tanneru, N.; Nivya, M. A.; Adhikari, N.; Saxena, K.; Rizvi, Z.; Sudhakar, R.; Nagwani, A. K.; Atul, ; Al-Nihmi, F. M. A.; Arun Kumar, K.; Sijwali, P. S.
10.1101/2021.10.29.466443 — cell biology — Posted on 2021-10-30
74 Impaired lamin localization to the nuclear envelope is responsible for nuclear damage in LMNA mutant iPSC-derived cardiomyocytes
Maurer, M.; Perati, S.; Johnson, L. E.; Gacita, A. M.; Lai, S.; Wallrath, L. L.; Benjamin, I. J.; McNally, E.; Kirby, T. J.; Lammerding, J.
10.1101/2021.10.30.466591 — cell biology — Posted on 2021-10-30
82 CaMKII binds both substrates and activators at the active site
Ozden, C.; Sloutsky, R.; Mitsugi, T.; Santos, N.; Agnello, E.; Gaubitz, C.; Foster, J.; Lapinskas, E.; Esposito, E. A.; Saneyoshi, T.; Kelch, B. A.; Garman, S. C.; Hayashi, Y.; Stratton, M.
10.1101/2020.10.25.354241 — biochemistry — Posted on 2021-10-30
83 Sirtuin-1 Sensitive Lysine-136 Acetylation Drives Phase Separation and Pathological Aggregation of TDP-43
Garcia Morato, J.; Hans, F.; von Zweydorf, F.; Feederle, R.; Elsaesser, S. J.; Skodras, A. A.; Gloeckner, C. J.; Buratti, E.; Neumann, M.; Kahle, P. J.
10.1101/2020.05.26.104356 — cell biology — Posted on 2021-10-30
84 A neural circuit basis for binasal input-enhanced chemosensory avoidance
Sy, S. K. H.; Chan, D. C. W.; Chan, R. C. H.; Lyu, J.; Li, Z.; Wong, K. K. Y.; Choi, C. H. J.; Mok, V. C. T.; Lai, H.-M.; Hu, Y.; Ko, H.
10.1101/2021.02.20.431946 — neuroscience — Posted on 2021-10-30
85 Blocking chondrocyte hypertrophy in conditional Evc knockout mice does not modify osteoarthritis progression
Lamuedra, A.; Gratal, P.; Calatrava, L.; Ruiz-Perez, V. L.; Palencia-Campos, A.; Portal-Nunez, S.; Mediero, A.; Herrero-Beaumont, G.; Largo, R.
10.1101/2021.10.29.466392 — pathology — Posted on 2021-10-30
87 The indoor mycobiome of daycare centers is affected by occupancy and climate
Estensmo, E. L.; Smebye Botnen, S.; Maurice, S.; Martin-Sanchez, P. M.; Morgado, L.; Bjorvand Engh, I.; Hoiland, K.; Skrede, I.; Kauserud, H.
10.1101/2021.10.28.466379 — microbiology — Posted on 2021-10-30
88 Stratification of the Gut Microbiota Composition Landscape Across the Alzheimer's Disease Continuum in a Turkish Cohort
Yildirim, S.; Nalbantoglu, O. U.; Bayraktar, A.; Ercan, F. B.; Gundogdu, A.; Velioglu, H. A.; Göl, M. F.; Soylu, A. E.; Koc, F.; Gürpınar, E. A.; Kadak, K. S.; Arikan, M.; Mardinoglu, A.; Kocak, M.; Köseoglu, E.; Hanoglu, L.
10.1101/2021.10.28.466378 — microbiology — Posted on 2021-10-30
89 Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
Hansen, J. Y.; Shafiei, G.; Markello, R. D.; Smart, K.; Cox, S. M.; Wu, Y.; Gallezot, J.-D.; Aumont, E.; Servaes, S.; Scala, S. G.; Dubois, J. M.; Wainstein, G.; Bezgin, G.; Funck, T.; Schmitz, T. W.; Spreng, R. N.; Soucy, J.-P.; Baillet, S.; Guimond, S.; Hietala, J.; Bedard, M.-A.; Leyton, M.; Kobayashi, E.; Rosa-Neto, P.; Palomero-Gallagher, N.; Shine, J.; Carson, R. E.; Tuominen, L.; Dagher, A.; Misic, B.
10.1101/2021.10.28.466336 — neuroscience — Posted on 2021-10-30
93 Membrane fission during bacterial spore development requires DNA-pumping driven cellular inflation
Landajuela, A.; Braun, M.; Martinez-Calvo, A.; Rodrigues, C. D. A.; Gomis Perez, C.; Doan, T.; Rudner, D. Z.; Wingreen, N. S.; Karatekin, E.
10.1101/2021.10.08.463650 — biophysics — Posted on 2021-10-30
94 High-Intensity Interval Training Remodels the Proteome and Acetylome of Human Skeletal Muscle
Hostrup, M.; Lemminger, A. K.; Stocks, B.; Gonzalez-Franquesa, A.; Larsen, J. K.; Prats, J. Q.; Thomassen, M.; Weinert, B.; Bangsbo, J.; Deshmukh, A. S.
10.1101/2021.02.10.430602 — physiology — Posted on 2021-10-30
95 Vocal tract allometry in a mammalian vocal learner
de Reus, K.; Carlson, D.; Lowry, A.; Gross, S.; Garcia, M.; Salazar Casals, A.; Rubio Garcia, A.; Ravignani, A.
10.1101/2021.10.29.466455 — animal behavior and cognition — Posted on 2021-10-30
97 Mispatterned motile cilia beating causes flow blockage in the epileptic brain
Faubel, R. J.; Feinstein, T. N.; Santos Canellas, V.; Gaesser, J.; Beluk, N. H.; Wang, Y.; Yankova, M.; King, S. M.; Karunakaran, K. B.; Ganapathiraju, M. K.; Lo, C. W.
10.1101/2021.10.29.465023 — neuroscience — Posted on 2021-10-30
99 The geometry of domain-general performance monitoring in the human medial frontal cortex
Fu, Z.; Beam, D.; Chung, J. M.; Reed, C. M.; Mamelak, A. N.; Adolphs, R.; Rutishauser, U.
10.1101/2021.07.08.451594 — neuroscience — Posted on 2021-10-29
100 Evolution and regulation of microbial secondary metabolism
Santamaria, G.; Liao, C.; Wang, Z.; Rhee, K.; Pinto, F.; Yan, J.; Xavier, J.
10.1101/2020.09.02.280495 — systems biology — Posted on 2021-10-29
102 Comprehensive Structure and Functional Adaptations of the Yeast Nuclear Pore Complex
Akey, C.; Singh, D.; Ouch, C.; Echeverria, I.; Nudelman, I.; Varberg, J. M.; Yu, Z.; Fang, F.; Shi, Y.; Wang, J.; Saltzberg, D.; Song, K.; Xu, C.; Gumbart, J.; Suslov, S.; Unruh, J.; Jaspersen, S. L.; Chait, B.; Sali, A.; Menendez-Martinez, J.; Ludke, S. J.; Villa, E.; Rout, M.
10.1101/2021.10.29.466335 — biophysics — Posted on 2021-10-29
108 Elevated Hoxb5b expands vagal neural crest pool and blocks enteric neuronal development in zebrafish
Howard, A. G. A.; Nguyen, A. C.; Tworig, J.; Ravisankar, P.; Singleton, E. W.; Li, C.; Kotzur, G.; Waxman, J. S.; Uribe, R. A.
10.1101/2021.10.28.466356 — developmental biology — Posted on 2021-10-29
110 Intracellular pH dynamics regulates intestinal stem cell fate
Barber, D. L.; Liu, Y.; Reyes, E.; Castillo-Azofeifa, D.; Klein, O. D.; Nystul, T.
10.1101/2021.10.28.466337 — cell biology — Posted on 2021-10-29
111 Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety
Watari, H.; Kageyama, H.; Masubuchi, N.; Nakajima, H.; Onodera, K.; Focia, P. J.; Oshiro, T.; Matsui, T.; Kodera, Y.; Ogawa, T.; Yokoyama, T.; Hirayama, M.; Hori, K.; Freymann, D. M.; Komatsu, N.; Araki, M.; Tanaka, Y.; Sakai, R.
10.1101/2021.10.29.466502 — cell biology — Posted on 2021-10-29
112 BET inhibitors synergize with anti-PD1 by rescuing TCF1+ progenitor exhausted CD8+ T cells in Acute Myeloid Leukemia
Romine, K. A.; Cho, H. J.; Kosaka, Y.; Byrd, K. H.; Coy, J. L.; Flynn, P. A.; Newman, M. T.; Loo, C.; Scott, J.; Lind, E. F.
10.1101/2021.08.04.455147 — cancer biology — Posted on 2021-10-29
113 Huntington's disease age at motor onset is modified by the tandem hexamer repeat in TCERG1
Lobanov, S. V.; McAllister, B.; McDade-Kumar, M.; Landwehrmeyer, G. B.; Orth, M.; Rosser, A. E.; REGISTRY Investigators of the European Huntington's disease network, ; Paulsen, J. S.; PREDICT-HD Investigators of the Huntington Study Group, ; Lee, J.-M.; MacDonald, M. E.; Gusella, J.; Long, J. D.; Ryten, M.; Williams, N.; Holmans, P.; Massey, T. H.; Jones, L.
10.1101/2021.07.16.452643 — genetics — Posted on 2021-10-29
115 Evolution of Natural Lifespan Variation and Molecular Strategies of Extended Lifespan
Kaya, A.; PHUA, C.-Z.-J.; Lee, M.; Wang, L.; Tyshkovskiy, A.; Ma, S.; Barre, B.; Liu, W.; Harrison, B.; Zhao, X.; Zhou, X.; Wasko, B. M.; Bammler, T. K.; Promislow, D. E. L.; Kaeberlein, M.; Gladyshev, V. N.
10.1101/2020.11.09.374488 — molecular biology — Posted on 2021-10-29
116 Fine-scale adaptations to environmental variation and growth strategies drive phyllosphere Methylobacterium diversity.
Leducq, J.-B.; Seyer-Lamontagne, E.; Condrain-Morel, D.; Bourret, G.; Sneddon, D.; Foster, J. A.; Marx, C. J.; Sullivan, J. M.; Shapiro, B. J.; Kembel, S. W.
10.1101/2021.06.04.447128 — microbiology — Posted on 2021-10-29
118 Cryo-sensitive aggregation triggers NLRP3 inflammasome assemblyin cryopyrin-associated periodic syndrome
Karasawa, T.; Komada, T.; Yamada, N.; Aizawa, E.; Mizushina, Y.; Watanabe, S.; Baatarjav, C.; Matsumura, T.; Takahashi, M.
10.1101/2021.10.05.463273 — immunology — Posted on 2021-10-29
121 RAF conformational autoinhibition and 14-3-3 proteins promote paradoxical activation
Mendiratta, G.; Abbott, K.; Li, Y.-C.; Yu, J.; Huang, J.; Shokhirev, M. N.; McFall, T.; Wahl, G. M.; Stites, E. C.
10.1101/849489 — cancer biology — Posted on 2021-10-29
125 A hold-and-feed mechanism drives directional DNA loop extrusion by condensin
Shaltiel, I. A.; Datta, S.; Lecomte, L.; Hassler, M.; Kschonsak, M.; Bravo, S.; Stober, C.; Eustermann, S.; Haering, C. H.
10.1101/2021.10.29.466147 — biochemistry — Posted on 2021-10-29
127 The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, are potent BACH1 inhibitors
Casares, L.; Moreno, R.; Higgins, M.; Naidu, S. D.; Neill, G.; Cassin, L.; Kiib, A. E.; Svenningsen, E. B.; Honda, T.; Poulsen, T. B.; Dinkova-Kostova, A. T.; Olagnier, D.; de la Vega, L.
10.1101/2021.10.29.466411 — cell biology — Posted on 2021-10-29
130 inPOSE: a flexible toolbox for chromosomal cloning and amplification of bacterial transgenes
Shukla, R. D.; Zvara, A.; Avramucz, A.; Biketova, A.; Nyerges, A.; Puskas, L. G.; Feher, T.
10.1101/2021.10.28.466346 — molecular biology — Posted on 2021-10-29
133 Clonal hematopoiesis detection in cancer patients using cell free DNA sequencing
Fairchild, L.; Whalen, J.; D'Aco, K.; Wu, J.; Gustafson, C. B.; Solovieff, N.; Su, F.; Leary, R.; Campbell, C. D.; Balbin, O. A.
10.1101/2021.10.27.466159 — cancer biology — Posted on 2021-10-29
134 Gata2b haploinsufficiency causes aberrant transcriptional signatures in HSPCs resulting in myeloid and erythroid dysplasia in zebrafish
Gioacchino, E.; Koyunlar, C.; Zink, J.; de Looper, H.; Gussinklo, K. J.; Hoogenboezem, R.; Bosch, D.; Bindels, E.; Touw, I. P.; de Pater, E.
10.1101/2021.10.29.466416 — cancer biology — Posted on 2021-10-29
135 Discovery of a conserved rule behind the assembly of β-barrel membrane proteins.
Germany, E. M.; Ding, Y.; Imai, K.; Bamert, R. S.; Dunstan, R. A.; Nakajima, Y.; Lai, X.; Webb, C. T.; Stubenrauch, C. J.; Hidaka, K.; Thewasano, N.; Tan, K. S.; Shen, H.-H.; Lithgow, T.; Shiota, T.
10.1101/2021.10.29.466387 — biochemistry — Posted on 2021-10-29
136 Modeling the efficacy of CRISPR gene drive for schistosomiasis control
Grewelle, R. E.; Perez-Saez, J.; Tycko, J.; Namigai, E. K.; Rickards, C. G.; De Leo, G. A.
10.1101/2021.10.29.466423 — genetics — Posted on 2021-10-29
137 Generating and testing the efficacy of transgenic Cas9 in Tribolium castaneum
Zelhof, A. C.; Rylee, J. C.; Nin-Velez, A.; Mahato, S.; Helms, K. J.; Wade, M. J.; Zentner, G. E.
10.1101/2021.10.28.466351 — genetics — Posted on 2021-10-29
141 Impact of antibiotic perturbation on intestinal viral communities in mice
Moltzau Anderson, J.; Lachnit, T.; Lipinski, S.; Falk-Paulsen, M.; Rosenstiel, P.
10.1101/2021.10.28.466382 — microbiology — Posted on 2021-10-29
142 Rare modification in the ergosterol biosynthesis pathway leads to amphotericin B resistance in Candida auris clinical isolates
Kordalewska, M.; Guerrero, K. D.; Mikulski, T. D.; Elias, T. N.; Garcia-Rubio, R.; Berrio, I.; Gardam, D.; Heath, C. H.; Chowdhary, A.; Govender, N. P.; Perlin, D. S.
10.1101/2021.10.22.465535 — microbiology — Posted on 2021-10-29
143 Application of Cas12j for Streptomyces editing and cluster activation
Tan, L. L.; Heng, E.; Zulkarnain, N.; Leong, C. Y.; Ng, V.; Yang, L. K.; Seow, D. C. S.; Peh, G.; Lim, Y. H.; Lokanand, K.; Kanagasundaram, Y.; Ng, S. B.; Wong, F. T.
10.1101/2021.10.28.465406 — microbiology — Posted on 2021-10-29
144 Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism
Magnotti, F.; Chirita, D.; Dalmon, S.; Martin, A.; Bronnec, P.; Sousa, J.; Helynck, o.; Lee, W.; Kastner, D.; Chae, J. J.; McDermott, M.; Belot, a.; Popoff, M.; Seve, P.; Georgin-Lavialle, S.; Munier-Lehmann, H.; TRAN, T. a.; De Langhe, E.; Wouters, C.; Jamilloux, Y.; Henry, T.
10.1101/2021.10.29.466454 — immunology — Posted on 2021-10-29
150 Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes
Guthrie, L.; Spencer, S.; Perelman, D.; Van Treuren, W.; Han, S.; Yu, F. B.; Sonnenburg, E.; Fischbach, M. A.; Meyer, T. W.; Sonnenburg, J.
10.1101/2021.10.29.465965 — microbiology — Posted on 2021-10-29
152 Camel nanobodies broadly neutralize SARS-CoV-2 variants
Hong, J.; Kwon, H. J.; Cachau, R.; Chen, C. Z.; Butay, K. J.; Duan, Z.; Li, D.; Ren, H.; Liang, T.; Zhu, J.; Dandey, V. P.; Martin, N. P.; Esposito, D.; Ortega-Rodriguez, U.; Xu, M.; Borgnia, M. J.; Xie, H.; Ho, M.
10.1101/2021.10.27.465996 — immunology — Posted on 2021-10-29
153 Dynamic Subcortical Modulators of Human Default Mode Network Function
Harrison, B. J.; Davey, C. G.; Savage, H. S.; Jamieson, A. J.; Leonards, C. A.; Moffat, B. A.; Glarin, R. K.; Steward, T.
10.1101/2021.10.27.466172 — neuroscience — Posted on 2021-10-29
154 Artifacts in EEG-based BCI therapies: friend or foe?
McDermott, E. J.; Raggam, P.; Kirsch, S.; Belardinelli, P.; Ziemann, U.; Zrenner, C.
10.1101/2021.10.27.466131 — neuroscience — Posted on 2021-10-29
156 Chemogenetic activation of Locus Coeruleus Noradrenergic Neurons Modulates the Default Mode Network
Oyarzabal, E. A.; Hsu, L.; Das, M.; Chao, T.-H. H.; Zhou, J.; Song, S.; Zhang, W.; Smith, K. G.; Sciolino, N. R.; Evsyukova, I. Y.; Yuan, H.; Lee, S.-H.; Cui, G.; Jensen, P.; Shih, Y.-Y. I.
10.1101/2021.10.28.463794 — neuroscience — Posted on 2021-10-29
157 Novel pectin from crude polysaccharide of Syzygium aromaticum against SARS-CoV-2 activities by targeting 3CLpro
Jin, C.; Feng, B.; Pei, R. j.; Ding, Y. q.; Li, M. x.; Chen, X.; Du, Z. y.; Ding, Y. x.; Huang, C. f.; Zhang, B.; Chen, X. w.; Zang, Y.; Li, J.; Ding, K.
10.1101/2021.10.27.466067 — pharmacology and toxicology — Posted on 2021-10-29
158 The glycosylated extracellular domain of MUC1 protects against SARS-CoV-2 infection at the respiratory surface
Chatterjee, M.; Huang, L. Z. X.; Wang, C.; Mykytyn, A. Z.; Westendorp, B.; Wubbolts, R. W.; Bosch, B. J.; Haagmans, B.; Putten, J. P. M. v.; Strijbis, K.
10.1101/2021.10.29.466408 — microbiology — Posted on 2021-10-29
159 SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade
Samsudin, F.; Raghuvamsi, P.; Petruk, G.; Puthia, M.; Petrlova, J.; MacAry, P.; Anand, G. S.; Schmidtchen, A.; Bond, P. J.
10.1101/2021.10.29.466401 — microbiology — Posted on 2021-10-29
160 Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates
Walters, J. N.; Schouest, B.; Patel, A.; Reuschel, E. L.; Schultheis, K.; Parzych, E.; Maricic, I.; Gary, E. N.; Purwar, M.; Andrade, V. M.; Doan, A.; Elwood, D.; Eblimit, Z.; Nguyen, B.; Frase, D.; Zaidi, F. I.; Kulkarni, A.; Generotti, A.; Kim, J. J.; Humeau, L. M.; Ramos, S. J.; Smith, T. R. F.; Weiner, D. B.; Broderick, K. E.
10.1101/2021.10.27.466163 — immunology — Posted on 2021-10-29
163 Phylogenetic analysis and in silico studies link spike Q675H mutation to SARS-CoV-2 adaptive evolution
Bertelli, A.; D'Ursi, P.; Campisi, G.; Messali, S.; Milanesi, M.; Giovanetti, M.; Ciccozzi, M.; Caccuri, F.; Caruso, A.
10.1101/2021.10.27.466055 — bioinformatics — Posted on 2021-10-29
164 A Potential Novel COVID-19 Vaccine With RBD-HR1/HR2 Hexamer Structure
Liu, H.; Gao, X.; Wang, G.; Zhang, J.; Zhou, J.; Wei, T.; Zhang, Y.; Liu, Y.; Piao, J.; Zhang, Q.; Wang, Y.; Ma, X.; Zhu, X.; Rao, Y.; Xia, W.; Xie, H.; Zhang, W.
10.1101/2021.10.28.465226 — biochemistry — Posted on 2021-10-29
165 Whole-genome sequencing of Vero E6 (C1008) and comparative analysis of four Vero cell sublines
Konishi, K.; Yamaji, T.; Sakuma, C.; Kasai, F.; Endo, T.; Kohara, A.; Hanada, K.; Osada, N.
10.1101/2021.10.26.466002 — genomics — Posted on 2021-10-29
166 A multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity
Gomez-Carballa, A.; Rivero-Calle, I.; Pardo-Seco, J.; Gomez-Rial, J.; Rivero-Velasco, C.; Rodriguez-Nunez, N.; Barbeito-Castineiras, G.; Perez-Freixo, H.; Cebey-Lopez, M.; Barral-Arca, R.; Rodriguez-Tenreiro, C.; Dacosta-Urbieta, A.; Bello, X.; Pischedda, S.; Curras-Tuala, M. J.; Viz-Lasheras, S.; Martinon-Torres, F.; Salas, A.; GEN-COVID,
10.1101/2021.10.27.466206 — genomics — Posted on 2021-10-29
167 An iTSC-derived placental model of SARS-CoV-2 infection unveils ACE2-dependent susceptibility in syncytiotrophoblasts
Chen, J.; Neil, J. A.; Tan, J. P.; Rudraraju, R.; Mohenska, M.; Sun, Y. B.; Sun, G.; Zhou, Y.; Li, Y.; Drew, D.; Pymm, P.; Tham, W.-H.; Rossello, F. J.; Nie, G.; Liu, X.; Subbarao, K.; Polo, J. M.
10.1101/2021.10.27.465224 — cell biology — Posted on 2021-10-29
168 Translating outcomes from the clinical setting to preclinical models: chronic pain and functionality in chronic musculoskeletal pain
Lenert, M. E.; Gomez, R.; Lane, B. T.; Dailey, D. L.; Vance, C. G. T.; Rakel, B. A.; Crofford, L. J.; Sluka, K. A.; Merriwether, E. N.; Burton, M. D.
10.1101/2021.10.27.466137 — neuroscience — Posted on 2021-10-29
169 Vagus nerve stimulation accelerates motor learning through cholinergic modulation
Bowles, S.; Hickman, J.; Peng, X.; Williamson, W. R.; Huang, R.; Washington, K.; Donegan, D.; Welle, C.
10.1101/2021.10.28.466306 — neuroscience — Posted on 2021-10-29
170 Efficient, selectable marker free gene targeting in soybean using novel Ochrobactrum haywardense-mediated delivery
Kumar, S.; Lui, Z.-B.; Sanyour-Doyel, N.; Landerts, B.; Worden, A.; Anand, A.; Cho, H.-J.; Bolar, J.; Harris, C.; Huang, L.; Xing, A.; Richardson, A.
10.1101/2021.10.28.466326 — plant biology — Posted on 2021-10-29
173 Causal Haplotype Block Identification in Plant Genome-Wide Association Studies
Wu, X.; Jiang, W.; Fragoso, C.; Huang, J.; Zhou, G.; Zhao, H.-y.; Dellaporta, S.
10.1101/2021.10.28.466332 — bioinformatics — Posted on 2021-10-29
175 Sequencing Micronuclei Reveals the Landscape of Chromosomal Instability
Pereira, C.; Rebelo, A. R.; Massey, D.; Schimenti, J. C.; Weiss, R. S.; Koren, A.
10.1101/2021.10.28.466311 — genomics — Posted on 2021-10-29
178 Allele frequency dynamics under sex-biased demography and sex-specific inheritance in a pedigreed population
Driscoll, R. M. H.; Beaudry, F. E. G.; Cosgrove, E. J.; Bowman, R.; Fitzpatrick, J. W.; Schoech, S. J.; Chen, N.
10.1101/2021.10.28.466320 — evolutionary biology — Posted on 2021-10-29
179 Reproduction, seasonal morphology, and juvenile growth in three Malagasy fruit bats
Andrianiaina, A.; Andry, S.; Gentles, A.; Guth, S.; Heraud, J.-M.; Ranaivoson, H. C.; Ravelomanantsoa, N. A. F.; Treuer, T.; Brook, C. E.
10.1101/2021.10.28.466299 — ecology — Posted on 2021-10-29
181 Modelling human zygotic genome activation in 8C-like cells in vitro
Taubenschmid-Stowers, J.; Rostovskaya, M.; Santos, F.; Ljung, S.; Argelaguet, R.; Krueger, F.; Nichols, J.; Reik, W.
10.1101/2021.10.28.466259 — molecular biology — Posted on 2021-10-29
182 RACK1 associates with RNA-binding proteins Vigilin and SERBP1 to control dengue virus replication
Brugier, A.; Hafirassou, M.-L.; Pourcelot, M.; Baldaccini, M.; Couture, L.; Kril, V.; Kuemmerer, B.; Gallois-Montbrun, S.; Bonnet-Madin, L.; Pfeffer, S.; Vidalain, P.-O.; Delaugerre, C.; Meertens, L.; Amara, A.
10.1101/2021.10.28.466260 — microbiology — Posted on 2021-10-29
186 Cortical adaptation to sound reverberation
Ivanov, A. Z.; King, A. J.; Willmore, B.; Walker, K. M. M.; Harper, N. S.
10.1101/2021.10.28.466271 — neuroscience — Posted on 2021-10-29
187 Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in juvenile rats
Jadhav, K.; Bernheim, A.; Aeschlimann, L.; Kirschmann, G.; Decosterd, I.; Hoffman, A.; Lupica, C. R.; Boutrel, B.
10.1101/2021.10.28.466154 — neuroscience — Posted on 2021-10-29
189 A viral toolbox for conditional and transneuronal gene expression in zebrafish
Satou, C.; Neve, R. L.; Oyibo, H. K.; Arn Bouldoires, E.; Mori, T.; Higashijima, S.-i.; Keller, G. B.; Friedrich, R. W.
10.1101/2021.03.25.436574 — neuroscience — Posted on 2021-10-29
192 Engineered bacteria detect tumor DNA
Cooper, R. M.; Wright, J. A.; Ng, J. Q.; Goyne, J. M.; Suzuki, N.; Lee, Y. K.; Ichinose, M.; Radford, G.; Thomas, E. M.; Vrbanac, L.; Knight, R.; Woods, S. L.; Worthley, D. L.; Hasty, J.
10.1101/2021.09.10.459858 — synthetic biology — Posted on 2021-10-29
195 OBERON3 and SUPPRESSOR OF MAX2 1-LIKE proteins form a regulatory module specifying phloem identity
Wallner, E.-S.; Tonn, N.; Shi, D.; Luzzietti, L.; Wanke, F.; Hunziker, P.; Xu, Y.; Jung, I.; Lopez-Salmeron, V.; Gebert, M.; Wenzl, C.; Lohmann, J. U.; Harter, K.; Greb, T.
10.1101/2019.12.21.885863 — plant biology — Posted on 2021-10-29
199 Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies
Sawada, H.; Katsumata, Y.; Higashi, H.; Zhang, C.; Li, Y.; Morgan, S.; Lee, L. H.; Singh, S. A.; Chen, J. Z.; Howatt, D. A.; Moorleghen, J. J.; Franklin, M. K.; Rateri, D. L.; Shen, Y. H.; LeMaire, S. A.; Aikawa, M.; Majesky, M. W.; Lu, H. S.; Daugherty, A.
10.1101/2020.02.02.930917 — pathology — Posted on 2021-10-29
201 Effect of eribulin on angiogenesis and endothelial adhesion molecules.
Abbona, A.; Falletta, A.; Paccagnella, M.; Astigiano, S.; Martini, S.; Denaro, N.; Ruatta, F.; Barbieri, O.; Merlano, M. C.; Garrone, O.
10.1101/2021.10.28.466220 — cancer biology — Posted on 2021-10-29
204 Alu-mediated weak CEBPA binding and slow B cell transdifferentiation in human
Nurtdinov, R.; Sanz, M.; Abad, A.; Esteban, A.; Ullrich, S.; Arnan, C.; Johnson, R.; Perez-Lluch, S.; Guigo, R.
10.1101/2021.10.28.466072 — bioinformatics — Posted on 2021-10-29
205 ColabFold - Making protein folding accessible to all
Mirdita, M.; Schuetze, K.; Moriwaki, Y.; Heo, L.; Ovchinnikov, S.; Steinegger, M.
10.1101/2021.08.15.456425 — bioinformatics — Posted on 2021-10-29
206 Computational Fontan Analysis: Preserving accuracy while expediting workflow
Liu, X.; Aslan, S.; Kim, B.; Warburton, L.; Jackson, D.; Muhuri, A.; Subramanian, A.; Mass, P.; Cleveland, V.; Loke, Y.-H.; Hibino, N.; Olivieri, L.; Krieger, A.
10.1101/2021.10.28.466272 — bioinformatics — Posted on 2021-10-29
210 Divergent evolutionary trajectories of bryophytes and tracheophytes from a complex common ancestor of land plants
Harris, B. J.; Clark, J. W.; Schrempf, D.; Szöllosi, G. J.; Donoghue, P.; Hetherington, A. M.; Williams, T. A.
10.1101/2021.10.28.466308 — evolutionary biology — Posted on 2021-10-29
211 Tubular lysosome induction couples animal starvation to healthy aging
Villalobos, T. V.; Ghosh, B.; Alam, S.; Butsch, T. J.; Mercola, B. M.; Ramos, C. D.; Das, S.; Eymard, E. D.; Bohnert, K. A.; Johnson, A. E.
10.1101/2021.10.28.466256 — cell biology — Posted on 2021-10-29
216 Untargeted metabolomic analyses reveal the diversity and plasticity of the specialized metabolome in seeds of different Camelina sativa genotypes
Boutet, S.; Barreda, L.; Perreau, F.; Totozafy, J.-C.; Mauve, C.; Gakiere, B.; Delannoy, E.; Martin-Magniette, M.-L.; Monti, A.; Lepiniec, L.; Zanetti, F.; Corso, M.
10.1101/2021.01.18.427130 — plant biology — Posted on 2021-10-29
219 Electrocorticography is superior to subthalamic local field potentials for movement decoding in Parkinson's disease
Merk, T.; Peterson, V.; Lipski, W.; Blankertz, B.; Turner, R. S.; Li, N.; Horn, A.; Richardson, M.; Neumann, W.-J.
10.1101/2021.04.24.441207 — neuroscience — Posted on 2021-10-29
220 Long-Term Inactivation of Sodium Channels as a Mechanism of Adaptation in CA1 Pyramidal Neurons
Upchurch, C.; Combe, C. L.; Knowlton, C.; Rousseau, V. G.; Gasparini, S.; Canavier, C. C.
10.1101/2021.10.26.465936 — neuroscience — Posted on 2021-10-29
221 Relating neural oscillations to laminar fMRI connectivity
Scheeringa, R.; Bonnefond, M.; van Mourik, T.; Jensen, O.; Norris, D. G.; Koopmans, P. J.
10.1101/2020.09.18.303263 — neuroscience — Posted on 2021-10-29
222 β-catenin and canonical Wnts in Hydra pattern formation: Insights from mathematical modelling into two distinct systems
Mercker, M.; Kazarnikov, A.; Tursch, A.; Höger, S.; Lengfeld, T.; Özbek, S.; Holstein, T. W.; Marciniak-Czochra, A.
10.1101/2021.02.05.429954 — developmental biology — Posted on 2021-10-29
224 Appropriate tension sensitivity of α-catenin ensures rounding morphogenesis of epithelial spheroids
Nishimura, R.; Kato, K.; Saida, M.; Kamei, Y.; Takeda, M.; Miyoshi, H.; Yamagata, Y.; Amano, Y.; Yonemura, S.
10.1101/2021.10.27.466008 — cell biology — Posted on 2021-10-29
227 Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis
Schwager, S. C.; Hapach, L. A.; Carlson, C. M.; Mosier, J. A.; McArdle, T. J.; Wang, W.; Jayathilake, A. L.; Bordeleau, F.; Antonyak, M. A.; Cerione, R. A.; Reinhart-King, C. A.
10.1101/2021.10.27.466095 — cancer biology — Posted on 2021-10-29
228 Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages
Howick, V. M.; Peacock, L.; Kay, C.; Collett, C.; Gibson, W.; Lawniczak, M. K.
10.1101/2021.10.13.463681 — genomics — Posted on 2021-10-29
230 Listeria monocytogenes GlmR is an accessory uridyltransferase essential for cytosolic survival and virulence
Pensinger, D.; Gutierrez, K. V.; Smith, H. B.; Vincent, W. J. B.; Stevenson, D. M.; Black, K. A.; Perez-Medina, K. M.; Dillard, J. P.; Rhee, K. Y.; Amador-Noguez, D.; Huynh, T. N.; Sauer, J.-D.
10.1101/2021.10.27.466214 — microbiology — Posted on 2021-10-29
231 Presence of Toxoplasma gondii tissue cysts in human semen
Tong, W. H.; Hlavacova, J.; Abdulai-Saiku, S.; Kankova, S.; Flegr, J.; Vyas, A.
10.1101/2021.10.27.466215 — microbiology — Posted on 2021-10-29
232 Increased biting rate and decreased Wolbachia density in irradiated mosquitoes
Moretti, R.; Lampazzi, E.; Damiani, C.; Fabbri, G.; Lombardi, G.; Pioli, C.; Desiderio, A.; Serrao, A.; Calvitti, M.
10.1101/2021.02.23.432445 — microbiology — Posted on 2021-10-29
234 MDA-LDL vaccination induces athero-protective germinal center-derived antibody responses
Martos-Folgado, I.; Lorenzo, C.; Busse, C. E.; Delgado, P.; Mur, S. M.; Cobos, L.; Martin-Ventura, J. L.; Escola-Gil, J. C.; Wardemann, H.; Ramiro, A. R.
10.1101/2021.10.25.465690 — immunology — Posted on 2021-10-29
235 Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model
Jendrach, M.; Freitag, K.; Sterczyk, N.; Obermayer, B.; Schulz, J.; Houtman, J.; Fleck, L.; Braeuning, C.; Sanseverino, R.; Hoffmann, C.; Milovanovic, D.; Sigrist, S. J.; Conrad, T.; Beule, D.; Heppner, F. L.
10.1101/2021.10.28.466219 — neuroscience — Posted on 2021-10-29
236 TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
Laurent, A.; Madigou, T.; Bizot, M.; Turpin, M.; Palierne, G.; Mahe, E.; Guimard, S.; Metivier, R.; Avner, S.; Le Peron, C.; Salbert, G.
10.1101/2021.10.27.466063 — cancer biology — Posted on 2021-10-29
238 Acetylation regulates the oligomerization state and activity of RNase J, the major ribonuclease of Helicobacter pylori
Tejada-Arranz, a.; Bouilloux-Lafont, M.; PEI, X.-Y.; Douche, T.; Matondo, M.; Williams, A.; Raynal, B.; Luisi, B.; DE REUSE, H.
10.1101/2021.08.09.455701 — microbiology — Posted on 2021-10-29
240 Distinct cellular origins and differentiation process account for distinct oncogenic and clinical behaviors of leiomyosarcomas
Darbo, E.; Perot, G.; Darmusey, L.; Le Guellec, S.; Leroy, L.; Gaston, L.; Desplat, N.; Thebault, N.; Merle, C.; Rochaix, P.; Valentin, T.; Ferron, G.; Chevreau, C.; Bui, B.; Stoeckle, E.; Ranchere-Vince, D.; Meeus, P.; Terrier, P.; Piperno-Neumann, S.; Collin, F.; De Pinieux, G.; Duffaud, F.; Coindre, J.-M.; Blay, J.-Y.; Chibon, F.
10.1101/2020.10.23.352336 — cancer biology — Posted on 2021-10-29
241 Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics
Furtwängler, B.; Üresin, N.; Motamedchaboki, K.; Huguet, R.; Lopez-Ferrer, D.; Zabrouskov, V.; Porse, B. T.; Schoof, E. M.
10.1101/2021.08.16.456445 — biochemistry — Posted on 2021-10-29
242 Ecological Network assembly: how the regional meta web influence local food webs
Saravia, L. A.; Marina, T. I.; Kristensen, N. P.; De Troch, M.; Momo, F. R.
10.1101/340430 — ecology — Posted on 2021-10-29
245 Genomically Mined Acoustic Reporter Genes Enable In Vivo Monitoring of Tumors and Tumor-Homing Bacteria
Hurt, R. C.; Buss, M. T.; Duan, M.; Wong, K.; You, M. Y.; Sawyer, D. P.; Swift, M. B.; Dutka, P.; Mittelstein, D. R.; Jin, Z.; Abedi, M. H.; Farhadi, A.; Deshpande, R.; Shapiro, M. G.
10.1101/2021.04.26.441537 — bioengineering — Posted on 2021-10-29
246 Machine learning algorithms in big data analyses identify determinants of insulin gene transcription
Wong, W. K.; Thorat, V.; Joglekar, M. V.; Dong, C. X.; Lee, H.; Chew, Y. V.; Bhave, A.; Hawthorne, W. J.; Engin, F.; Pant, A.; Dalgaard, L. T.; Bapat, S.; Hardikar, A. A.
10.1101/2021.03.27.437353 — genetics — Posted on 2021-10-29
250 FiberNeat: unsupervised streamline clustering and white matter tract filtering in latent space
Chandio, B. Q.; Chattopadhyay, T.; Owens-Walton, C.; Villalon Reina, J. E.; Nabulsi, L.; Thomopoulos, S. I.; Garyfallidis, E.; Thompson, P. M.
10.1101/2021.10.26.465991 — neuroscience — Posted on 2021-10-28
251 The geometry of domain-general performance monitoring in the human medial frontal cortex
Fu, Z.; Beam, D.; Chung, J. M.; Reed, C. M.; Mamelak, A. N.; Adolphs, R.; Rutishauser, U.
10.1101/2021.07.08.451594 — neuroscience — Posted on 2021-10-28
252 Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner
Wakefield, C. B.; Lee, V. R.; Johnston, D.; Boroumand, P.; Pillon, N. J.; Sayedyahossein, S.; O'Donnell, B. L.; Tang, J.; Sanchez-Pupo, R. E.; Barr, K. J.; Gros, R.; Flynn, L. E.; Borradaile, N.; Klip, A.; Beier, F.; Penuela, S.
10.1101/2021.05.04.442670 — physiology — Posted on 2021-10-28
253 Coevolution of brain size and longevity in parrots
Smeele, S. Q.; Conde, D. A.; Baudisch, A.; Bruslund, S.; Iwaniuk, A.; Staerk, J.; Wright, T. F.; Young, A. M.; McElreath, M. B.; Aplin, L.
10.1101/2021.10.28.466243 — evolutionary biology — Posted on 2021-10-28
254 Cephalopod Retinal Development Shows Vertebrate-like Mechanisms of Neurogenesis
Napoli, F.; Daly, C. M.; Neal, S.; McCulloch, K. J.; Zaloga, A.; Liu, A.; Koenig, K. M.
10.1101/2021.10.28.466353 — developmental biology — Posted on 2021-10-28
256 Sciara coprophila larvae upregulate DNA repair pathways and downregulate developmental regulators in response to ionizing radiation
Urban, J. M.; Bateman, J. R.; Garza, K. R.; Borden, J.; Jain, J.; Brown, A.; Thach, B.; Bliss, J.; Gerbi, S. A.
10.1101/2021.10.28.466123 — genomics — Posted on 2021-10-28
259 Temperature-induced prophage dictates evolution of virulence in bacteria
Bruneaux, M.; Ashrafi, R.; Kronholm, I.; Laanto, E.; Örmälä-Odegrip, A.-M.; Galarza, J. A.; Chen, Z.; Kubendran Sumathi, M.; Ketola, T.
10.1101/850248 — evolutionary biology — Posted on 2021-10-28
261 Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum
Lu, C.-L.; Ortmeier, S.; Brudvig, J.; Moretti, T.; Cain, J.; Boyadjiev, S.; Weimer, J. M.; Kim, J.
10.1101/2021.02.23.431880 — cell biology — Posted on 2021-10-28
262 Molecular identification of rhizobacterial isolates from Prosopis limensis and their effect on the growth of Raphanus sativus under salt stress
Clavo, R. F.; Valladolid Suyon, E. A.; Reynoza Farronan, K. J.; Ortega, C. D. A.; Valdera, G. Z.; Garboggini, F. F.; Iglesias-Osores, S.; Carreno Farfan, C. R.
10.1101/2021.10.25.464584 — molecular biology — Posted on 2021-10-28
266 A viral toolbox for conditional and transneuronal gene expression in zebrafish
Satou, C.; Neve, R. L.; Oyibo, H. K.; Zmarz, P.; Huang, K.-H.; Arn Bouldoires, E.; Mori, T.; Higashijima, S.-i.; Keller, G. B.; Friedrich, R. W.
10.1101/2021.03.25.436574 — neuroscience — Posted on 2021-10-28
270 Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis
El Houari, I.; Klima, P.; Baekelandt, A.; Staswick, P.; Uzunova, V.; del Genio, C. I.; Steenackers, W.; Dobrev, P. I.; Novak, O.; Napier, R. M.; Petrasek, J.; Inze, D.; Boerjan, W.; Vanholme, B.
10.1101/2021.10.27.466161 — plant biology — Posted on 2021-10-28
271 Large1 Gene Transfer in Older myd Mice with Severe Muscular Dystrophy Restores Muscle Function and Greatly Improves Survival
Yonekawa, T.; Rauckhorst, A. J.; El-Hattab, S. Y.; Cuellar, M. A.; Venzke, D.; Anderson, M. E.; Okuma, H.; Pewa, A. D.; Taylor, E. B.; Campbell, K. P.
10.1101/2021.10.28.466309 — physiology — Posted on 2021-10-28
272 Mechanism of transcription modulation by the transcription-repair coupling factor
Paudel, B. P.; Xu, Z.-Q.; Jergic, S.; Oakley, A. J.; Sharma, N.; Brown, S. H.; Bouwer, J. C.; Lewis, P.; Dixon, N. E.; van Oijen, A. M.; Ghodke, H.
10.1101/2021.04.02.438179 — biophysics — Posted on 2021-10-28
273 Transfer of Knowledge from Model Organisms to Evolutionarily Distant Non-Model Organisms: The Coral Pocillopora damicornis Membrane Signaling Receptome
Kumar, L.; Brenner, N.; Sledzieski, S.; Olaosebikan, M.; Lynn-Goin, M.; Putnam, H.; Yang, J.; Lewinski, N.; Singh, R.; Daniels, N.; Cowen, L.; Klein-Seetharaman, J. H.
10.1101/2021.10.18.464760 — bioinformatics — Posted on 2021-10-28
275 Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells
Srivastava, P.; Romanazzo, S.; Ireland, J.; Nemec, S.; Molley, T. G.; Jayathilaka, P.; Pandzic, E.; Yeola, A.; Chandrakanthan, V.; Pimanda, J.; Kilian, K.
10.1101/2021.10.28.466327 — bioengineering — Posted on 2021-10-28
277 Regulation Mechanisms of the Dual ATPase in KaiC
Furuike, Y.; Mukaiyama, A.; Koda, S.-i.; Simon, D.; Ouyang, D.; Ito-Miwa, K.; Saito, S.; Yamashita, E.; Nishiwaki-Ohkawa, T.; Terauchi, K.; Kondo, T.; Akiyama, S.
10.1101/2021.10.28.466029 — biochemistry — Posted on 2021-10-28
278 Genetic Analyses of Epigenetic Predictors that Estimate Aging, Metabolic Traits, and Lifespan
Mozhui, K.; Lu, A.; Li, C. Z.; Haghani, A.; Sandoval-Sierra, J. V.; Williams, R. W.; Horvath, S.
10.1101/2021.06.23.449634 — genomics — Posted on 2021-10-28
279 Distinct mechanoreceptor pezo-1 isoforms modulate food intake in the nematode Caenorhabditis elegans
Hughes, K. J.; Shah, A.; Bai, X.; Adams, J.; Bauer, R.; Jackson, J.; Harris, E.; Ficca, A.; Freebairn, P.; Mohammed, S.; Fernandez, E. M.; Bainbridge, C.; Brocco, M.; Stein, W.; Vidal-Gadea, A. G.
10.1101/2021.05.24.445504 — genetics — Posted on 2021-10-28
281 Temperature predicts leaf shape in palms (Arecaceae)
Jimenez, M. F. T.; Chazot, N.; Emilio, T.; Fredin, J. U.; Antonelli, A.; Faurby, S.; Bacon, C. D.
10.1101/2021.10.26.465896 — evolutionary biology — Posted on 2021-10-28
286 Map7D2 and Map7D1 facilitate MT stabilization through distinct mechanisms to control cell motility and neurite outgrowth
Kikuchi, K.; Sakamoto, Y.; Uezu, A.; Yamamoto, H.; Ishiguro, K.-i.; Shimamura, K.; Saito, T.; Hisanaga, S.-i.; Nakanishi, H.
10.1101/2021.10.27.466197 — cell biology — Posted on 2021-10-28
288 Genetically distant bacteriophages elicit unique genomic changes in Enterococcus faecalis
Johnson, C. N.; Araya, D. P.; Schink, V.; Islam, M.; Mangalea, M. R.; Decurtis, E. K.; Ngo, T.-V. C.; Palmer, K. L.; Duerkop, B. A.
10.1101/2021.10.28.466302 — microbiology — Posted on 2021-10-28
289 Establishment of quantitative RNAi-based forward genetics in Entamoeba histolytica and identification of genes required for growth
Bettadapur, A.; Hunter, S. S.; Suleiman, R. L.; Ruyechan, M. C.; Huang, W.; Barbieri, C. G.; Miller, H. W.; Tam, T. S. Y.; Settles, M. L.; Ralston, K. S.
10.1101/2020.05.28.121780 — microbiology — Posted on 2021-10-28
290 Dormant spores sense amino acids through the B subunits of their germination receptors
Artzi, L.; Alon, A.; Brock, K. P.; Green, A. G.; Tam, A.; Ramirez-Guadiana, F. H.; Marks, D.; Kruse, A.; Rudner, D. Z.
10.1101/2021.10.28.466322 — microbiology — Posted on 2021-10-28
291 GATA4 regionalizes intestinal metabolism and barrier function to prevent immunopathology
Earley, Z. M.; Lisicka, W.; Sifakis, J. J.; Gamboa, R. A.; Kowalczyk, A.; Barlow, J.; Shaw, D. G.; Discepolo, V.; Tan, I. L.; Gona, S.; Ernest, J.; Matzinger, P.; Barreiro, L. B.; Morgun, A.; Bendelac, A.; Ismagilov, R. F.; Shulzhenko, N.; Riesenfeld, S. J.; Jabri, B.
10.1101/2021.10.28.466194 — immunology — Posted on 2021-10-28
292 In-depth immunophenotyping with mass cytometry during TB treatment reveals non-canonical T-cell subsets associated with sputum culture conversion.
Chedid, C.; Andrieu, T.; Kokhreidze, E.; Tukvadze, N.; Biswas, S.; Ather, M. F.; Uddin, M. K. M.; Banu, S.; De Maio, F.; Delogu, G.; Endtz, H.; Goletti, D.; Vocanson, M.; Dumitrescu, O.; Hoffmann, J.; Ader, F.
10.1101/2021.10.27.466125 — immunology — Posted on 2021-10-28
294 In Vivo MRI of Endogenous Remyelination in a Nonhuman Primate Model of Multiple Sclerosis
Lee, N. J.; Sati, P.; Ha, S.-K.; Luciano, N. J.; Roy, S.; Ineichen, B. V.; Leibovitch, E. C.; Yen, C. C.; Pham, D. L.; Silva, A. C.; Johnson, M.; Jacobson, S.; Reich, D. S.
10.1101/2021.10.27.466044 — neuroscience — Posted on 2021-10-28
295 Mecp2 deletion results in profound alterations of developmental and adult functional connectivity
Rahn, R. M.; Yen, A.; Chen, S.; Gaines, S. H.; Bice, A. R.; Brier, L. M.; Swift, R. G.; Lee, L.; Maloney, S. E.; Culver, J. P.; Dougherty, J. D.
10.1101/2021.10.28.466323 — neuroscience — Posted on 2021-10-28
296 Selective Vulnerability of Tripartite Synapses in Amyotrophic Lateral Sclerosis.
Broadhead, M. J.; Bonthron, C.; Waddington, J.; Smith, W. V.; Lopez, M. F.; Burley, S.; Valli, J.; Zhu, F.; Komiyama, N. H.; Smith, C.; Grant, S. G.; Miles, G. B.
10.1101/2021.10.28.465435 — neuroscience — Posted on 2021-10-28
298 The gut microbiome is associated with cocaine behavior and predicts addiction vulnerability in adult male rats
Suess, G. J.; Kasiah, J.; Simpson, S.; Brennan, M.; Conlisk, D.; Maturin, L.; George, O.; Chassaing, B.; Frantz, K. J.
10.1101/2021.07.20.453110 — neuroscience — Posted on 2021-10-28
299 Network Reconstruction from Perturbation Time Course Data
Smith, G. R.; Sarmah, D.; Bouhaddou, M.; Stern, A. D.; Erskine, J.; Birtwistle, M.
10.1101/341008 — systems biology — Posted on 2021-10-28
303 Disordered yet functional atrial t-tubules on recovery from heart failure
Caldwell, J. L.; Clarke, J. D.; Smith, C. E. R.; Pinali, C.; Quinn, C. J.; Pearman, C. M.; Adomaviciene, A.; Radcliffe, E. J.; Watkins, A. E.; Horn, M. A.; Bode, E. F.; Eisner, M.; Eisner, D. A.; Trafford, A. W.; Dibb, K. M.
10.1101/2021.10.28.466162 — physiology — Posted on 2021-10-28
305 A Generalizable Speech Emotion Recognition Model Reveals Depression and Remission
Hansen, L.; Zhang, Y.-P.; Wolf, D.; Sechidis, K.; Ladegaard, N.; Fusaroli, R.
10.1101/2021.09.01.458536 — bioinformatics — Posted on 2021-10-28
308 CHD4 is recruited by GATA4 and NKX2-5 silencers to repress non-cardiac gene programs in the developing heart
Robbe, Z. L.; Shi, W.; Wasson, L. K.; Wilczewski, C. M.; Sheng, X.; Hepperla, A. J.; Akerberg, B. N.; Pu, W. T.; Cristea, I. M.; Davis, I. J.; Conlon, F. L.
10.1101/2021.10.28.466285 — genomics — Posted on 2021-10-28
309 Ecological Differentiation Among Globally Distributed Lineages of the Rice Blast Fungus Pyricularia oryzae
Thierry, M.; Charriat, F.; Milazzo, J.; Adreit, H.; Ravel, S.; Borron, S.; Sella, V.; Kroj, T.; Ioos, R.; Fournier, E.; Tharreau, D.; Gladieux, P.
10.1101/2020.06.02.129296 — evolutionary biology — Posted on 2021-10-28
312 ACTN2 missense variant causes proteopathy in human iPSC-derived cardiomyocytes
Orthey, E.; Zech, A. T.; Prondzynski, M.; Singh, S. R.; Alizoti, E.; Busch, J.; Madsen, A.; Behrens, C. S.; Mearini, G.; Lemoine, M. D.; Kraemer, E.; Mosqueira, D.; Virdi, S.; Inderbirken, D.; Depke, M.; Salazar, M. G.; Voelker, U.; Braren, I.; Pu, W. T.; Eschenhagen, T.; Hammer, E.; Schlossarek, S.; Carrier, L.
10.1101/2021.10.28.466251 — cell biology — Posted on 2021-10-28
315 Investigating pathogenicity and virulence of Staphylococcus pettenkoferi: an emerging pathogen
Plumet, L.; Ahmad-Mansour, N.; Huc-Brandt, S.; Magnan, C.; Yahiaoui-Martinez, A.; Kissa, K.; Pantel, A.; Lavigne, J.-P.; Molle, V.
10.1101/2021.10.28.466297 — microbiology — Posted on 2021-10-28
317 Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing
Cho, A.; Gaebler, C.; Olveira, T.; Ramos, V.; Saad, M.; Lorenzi, J.; Gazumyan, A.; Moir, S.; Chun, T.-W.; Caskey, M.; Nussenzweig, M.
10.1101/2021.10.28.466316 — immunology — Posted on 2021-10-28
318 Diverse B-cell specific transcriptional contexts of the BCL2 oncogene in mouse models impacts pre-malignant development
Zawil, L.; Marchiol, T.; Brauge, B.; Saint-Amand, A.; Carrion, C.; Dessauge, E.; Oblet, C.; Le Noir, S.; Mourcin, F.; Jouan, F.; Derouault, P.; Alizadeh, M.; Brousse, M.; El Makhour, Y.; Monvoisin, C.; Leonard, S.; Durand-Panteix, S.; Tarte, K.; Cogne, M.
10.1101/2021.10.28.466164 — immunology — Posted on 2021-10-28
320 Brain macrophages acquire distinct transcriptomes prior to demyelination in multiple sclerosis
Miedema, A.; Gerrits, E.; Brouwer, N.; Jiang, Q.; Kracht, L.; Meijer, M.; Nutma, E.; Peferoen-Baert, R.; Pijnacker, A.; Wesseling, E.; Wijering, M.; Gabius, H.-J.; Amor, S.; Kooistra, S.; Eggen, B.
10.1101/2021.10.27.465877 — neuroscience — Posted on 2021-10-28
321 Microglia-specific promoter activities of human HexB gene
Shah, S.; Wong, L.; Ellis, K.; Bondar, B.; Saribas, S.; Ting, J.; Wei, Z.; Wang, X.; Wang, H.; Tang, Y.; Lin, B.; Margolis, D. M.; Garcia-Martinez, J. V.; Hu, W.; Jiang, G.
10.1101/2021.10.28.465974 — neuroscience — Posted on 2021-10-28
322 Reduced myofibroblast transdifferentiation and fibrotic scarring in ischemic stroke after imatinib treatment
Zeitelhofer, M.; Stefanitsch, C.; Protzmann, J.; Torrente, D.; Adzemovic, M. Z.; Lewandowski, S. A.; Muhl, L.; Eriksson, U.; Nilsson, I.; Su, E. J.; Lawrence, D. A.; Fredriksson, L.
10.1101/2021.10.28.466225 — neuroscience — Posted on 2021-10-28
326 Loss of p16INK4a in neuroblastoma cells induces shift to an immature state with mesenchymal characteristics and increases sensitivity to EGFR inhibitors
Schubert, N. A.; van Hooff, S. R.; Schild, L.; Ober, K.; Hortensius, M.; van den Handel, K.; Essing, A. H. W.; Koopmans, B.; Boeije, M.; Proost, N.; van de Ven, M.; Jansky, S.; Stainczyk, S. A.; Toprak, U. H.; Westermann, F.; Eising, S.; Molenaar, J. J.; van den Boogaard, M. L.
10.1101/2021.10.27.465137 — cancer biology — Posted on 2021-10-28
329 Curated Single Cell Multimodal Landmark Datasets for R/Bioconductor
Eckenrode, K.; Righelli, D.; Ramos, M.; Argelaguet, R.; Vanderaa, C.; Geistlinger, L.; Culhane, A.; Gatto, L.; Carey, V. J.; Morgan, M.; Risso, D.; Waldron, L. D.
10.1101/2021.10.27.466079 — bioinformatics — Posted on 2021-10-28
331 LungCancer3D: A Comprehensive Database for Integrating Lung Cancer Chromatin Architecture with Other Multi-omics
Wu, X.; Jiang, A.; Wang, J.; Song, S.; Xu, Y.; Tang, Q.; Zhang, S.; Xia, B.; Chen, X.; Ma, S.; Liu, J.
10.1101/2021.10.26.466013 — bioinformatics — Posted on 2021-10-28
334 Integration of GWAS and TWAS to elucidate the genetic architecture of natural variation for leaf cuticular conductance in maize
Lin, M.; Qiao, P.; Matschi, S.; Vasquez, M.; Ramstein, G. P.; Bourgault, R.; Mohammadi, M.; Scanlon, M. J.; Molina, I.; Smith, L. G.; Gore, M. A.
10.1101/2021.10.26.465975 — genetics — Posted on 2021-10-28
341 Plant secondary metabolite diversity reflects both phylogeny and ecological adaptation
Pierce, S.; Guo, W.-Y.; Cerabolini, B. E. L.; Negreiros, D.; Faoro, F.; Magoga, G.; Montagna, M.; Fernandes, G. W.; Spada, A.
10.1101/2021.10.26.465835 — ecology — Posted on 2021-10-28
342 Patient-derived endometrial organoids from MRKH patients: Insight in disease causing pathways
Brucker, S. Y.; Hentrich, T.; Schulze-Hentrich, J. M.; Pietzsch, M.; Wajngarten, N.; Singh, A. R.; Rall, K.; Koch, A.
10.1101/2021.10.27.466065 — developmental biology — Posted on 2021-10-28
343 Genomic diversity of hospital-acquired infections revealed through prospective whole genome sequencing-based surveillance
Mustapha, M. M.; Srinivasa, V. R.; Griffith, M. P.; Cho, S.-T.; Evans, D. R.; Waggle, K.; Ezeonwuka, C.; Snyder, D.; Marsh, J. W.; Harrison, L. H.; Cooper, V. S.; Van Tyne, D.
10.1101/2021.10.27.466213 — microbiology — Posted on 2021-10-28
347 Long-Term Inactivation of Sodium Channels as a Mechanism of Adaptation in CA1 Pyramidal Neurons
Upchurch, C.; Combe, C. L.; Knowlton, C.; Rousseau, V. G.; Gasparini, S.; Canavier, C. C.
10.1101/2021.10.26.465936 — neuroscience — Posted on 2021-10-28
348 Computational and neural mechanisms of affected beliefs
Müller-Pinzler, L.; Czekalla, N.; Mayer, A. V.; Schröder, A.; Stolz, D. S.; Paulus, F. M.; Krach, S.
10.1101/2021.10.26.465922 — neuroscience — Posted on 2021-10-28
353 FEMA: Fast and efficient mixed-effects algorithm for population-scale whole brain imaging data
Fan, C. C.; Palmer, C. E.; Iverson, J.; Pecheva, D.; Thompson, W. K.; Hagler, D.; Jernigan, T. L.; Dale, A. M.
10.1101/2021.10.27.466202 — neuroscience — Posted on 2021-10-28
354 On the dynamics of spatial updating
Blouin, J.; Pialasse, J.-P.; Mouchnino, L.; Simoneau, M.
10.1101/2021.10.27.465887 — paleontology — Posted on 2021-10-28
355 Eicosanoids in the pancreatic tumor microenvironment: a multicellular, multifaceted progression
Gubbala, V. B.; Jyotsana, N.; Trinh, V. Q.; Maurer, H. C.; Naeem, R. F.; Lytle, N. K.; Ma, Z.; Zhao, S.; Lin, W.; Han, H.; Shi, Y.; Hunter, T.; singh, P. K.; Olive, K. P.; Tan, M. C. B.; Kaech, S. M.; Wahl, G.; DelGiorno, K. E.
10.1101/2021.10.27.466097 — cancer biology — Posted on 2021-10-28
359 Techniques to Produce and Evaluate Realistic Multivariate Synthetic Data
Heine, J.; Fowler, E. E. E.; Berglund, A.; Schell, M. J.; Eschrich, S. A.
10.1101/2021.10.26.465952 — bioinformatics — Posted on 2021-10-28
362 Brain-inspired spiking neural network controller for a neurorobotic whisker system
Antonietti, A.; Geminiani, A.; Negri, E.; D'Angelo, E. U.; Casellato, C.; Pedrocchi, A.
10.1101/2021.10.26.465919 — bioengineering — Posted on 2021-10-28
363 Spatial-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density
Ahmed-Cox, A.; Pandzic, E.; Johnston, S. T.; Heu, C.; McGhee, J. B.; Mansfeld, F. M.; Crampin, E. J.; Davis, T. P.; Whan, R. M.; Kavallaris, M.
10.1101/2021.10.26.465839 — bioengineering — Posted on 2021-10-28
364 Ultra-cheap and scalable epigenetic age predictions with TIME-Seq
Griffin, P. T.; Kane, A. E.; Trapp, A.; Li, J.; McNamara, M. S.; Meer, M. V.; MacArthur, M. R.; Mitchell, S. J.; Mueller, A. L.; Carmody, C.; Vera, D. L.; Kerepesi, C.; Noren Hooten, N.; Mitchell, J. R.; Evans, M. K.; Gladyshev, V. N.; Sinclair, D. A.
10.1101/2021.10.25.465725 — genomics — Posted on 2021-10-28
365 Sex differences in migraine: A twin study
Fitzgerald, M. C.; Saelzler, U. G.; Panizzon, M. S.
10.1101/2021.10.27.466155 — genetics — Posted on 2021-10-28
368 Signaling from the RNA sensor RIG-I is regulated by ufmylation
Snider, D. L.; Park, M.; Murphy, K. A.; Beachboard, D. C.; Horner, S. M.
10.1101/2021.10.26.465929 — immunology — Posted on 2021-10-28
369 RNA sensing via LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency
Stok, J. E.; Oosenbrug, T.; ter Haar, L. R.; Gravekamp, D.; Bromley, C. P.; Zelenay, S.; Reis e Sousa, C.; van der Veen, A. G.
10.1101/2021.10.27.465188 — immunology — Posted on 2021-10-28
370 A simple strategy for sample annotation error detection in cytometry datasets
Smithmyer, M.; Wiedeman, A. E.; Skibinski, D. A. G.; Savage, A. K.; Acosta-Vega, C.; Scheiding, S.; Gersuk, V. H.; Long, S. A.; Buckner, J. H.; Speake, C.
10.1101/2021.10.26.465993 — immunology — Posted on 2021-10-28
371 Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells from HIV+ Controllers and Non-Controllers
George, A. F.; Luo, X.; Neidleman, J.; Hoh, R.; Vohra, P.; Thomas, R.; Shin, M.-G.; Lee, M. J.; Blish, C. A.; Deeks, S. G.; Greene, W. C.; Lee, S. A.; Roan, N. R.
10.1101/2021.10.27.466175 — immunology — Posted on 2021-10-28
372 Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritis
Wang, P.; Song, J.; Bai, M.; Zheng, X.; Xie, Y.; Tang, Y.; Li, X.; Fang, X.; Jia, Y.; Ren, L.; Ye, H.; Su, Y.; Wang, S.; Li, Z.; Hu, F.
10.1101/2021.10.27.466096 — immunology — Posted on 2021-10-28
373 Long-term effects of network-based fMRI neurofeedback training for sustained attention
Pamplona, G. S. P.; Heldner, J.; Langner, R.; Koush, Y.; Michels, L.; Ionta, S.; Garrido Salmon, C. E.; Scharnowski, F.
10.1101/2021.10.27.465722 — neuroscience — Posted on 2021-10-28
375 Inhibiting adult neurogenesis differentially affects spatial learning in females and males
O'Leary, T. P.; Askari, B.; Lee, B.; Darby, K.; Knudson, C.; Ash, A. M.; Seib, D. R.; Espinueva, D.; Snyder, J. S.
10.1101/2021.10.27.466135 — neuroscience — Posted on 2021-10-28
378 EEG microstate dynamics indicate a U-shaped path to propofol-induced loss of consciousness
Artoni, F.; Maillard, J.; Britz, J.; Seeber, M.; Lysakowski, C.; Brechet, L.; Tramer, M. R.; Michel, C. M.
10.1101/2021.10.26.465841 — neuroscience — Posted on 2021-10-28
381 Altered Salience Network Connectivity in 6-Week-Old Infants at Risk for Autism
Tsang, T.; Green, S.; Liu, J.; Lawrence, K.; Jeste, S.; Bookheimer, S.; Dapretto, M.
10.1101/2021.10.27.466195 — neuroscience — Posted on 2021-10-28
382 In vivo MR spectroscopy reflects synapse density in a Huntington's disease mouse model
Zarate, N.; Gundry, K.; Yu, D.; Casby, J.; Eberly, L. E.; Oz, G.; Gomez-Pastor, R.
10.1101/2021.10.26.465951 — neuroscience — Posted on 2021-10-28
383 KIBRA-PKCγ signaling pathway modulates memory performance in mice and humans
Tian, M.; Chen, Q.; Graves, A. R.; Goldschmidt, H. L.; Johnson, R. C.; Weinberger, D. R.; Huganir, R. L.
10.1101/2021.10.26.465926 — neuroscience — Posted on 2021-10-28
385 FiberNeat: unsupervised streamline clustering and white matter tract filtering in latent space
Chandio, B. Q.; Chattopadhya, T.; Owens-Walton, C.; Villalon Reina, J. E.; Nabulsi, L.; Thomopoulos, S. I.; Garyfallidis, E.; Thompson, P. M.
10.1101/2021.10.26.465991 — neuroscience — Posted on 2021-10-28
386 Single nuclear transcriptional signatures of dysfunctional brain vascular homeostasis in Alzheimer's disease
Tsartsalis, S.; Fancy, N.; Smith, A. M.; Khozoie, C.; Yang, X.; Davey, K.; Willumsen, N.; McGarry, A.; Muirhead, R. C. J.; Debette, S.; Owen, D. R.; Matthews, P. M.
10.1101/2021.10.27.465860 — neuroscience — Posted on 2021-10-28
389 Phylogeography of Lanius senator reveals conflicts between alpha taxonomy, subspecies ranges and genetics.
Nasuelli, M.; Ilahiane, L.; Boano, G.; Cucco, M.; Galimberti, A.; Pavia, M.; Pioltelli, E.; Shafaeipour, A.; Voelker, G.; Pellegrino, I.
10.1101/2021.10.27.466041 — zoology — Posted on 2021-10-28
391 Whole-genome sequence and methylome profiling of the almond (Prunus dulcis D.A.Webb) cultivar Nonpareil
D'Amico-Willman, K. M.; Ouma, W. Z.; Meulia, T.; Sideli, G. M.; Gradziel, T. M.; Fresnedo Ramirez, J.
10.1101/2021.10.27.466198 — plant biology — Posted on 2021-10-28
392 European Vintage tomatoes galore: a result of farmers combinatorial assorting/swapping of a few diversity rich loci
Blanca, J.; Pons, C.; Montero-Pau, J.; Sanchez-Matarredona, D.; Ziarsolo, P.; Fontanet, L.; Fisher, J.; Plazas, M.; Casals, J.; Rambla, J. L.; Riccini, A.; Pombarelli, S.; Ruggiero, A.; Sulli, M.; Grillo, S.; Kanellis, A. K.; Giuliano, G.; Finkers, R.; Cammareri, M.; Grandillo, S.; Mazzucato, A.; Causse, M.; Diez, M. J.; Prohens, J.; Zamir, D.; Canizares, J.; Monforte, A. J.; Granell, A.
10.1101/2021.10.26.465840 — plant biology — Posted on 2021-10-28
394 Computational analysis reveals similarities and differences between SCLC subtypes
Singh, A.; Desai, P.; Pillai, M.; Agarwal, N.; Takahashi, N.; Thomas, A.; Jolly, M. K.
10.1101/2021.10.27.465593 — cancer biology — Posted on 2021-10-28
396 Sequence dependencies and mutation rates of localized mutational processes in cancer
Poulsgaard, G. A.; Sorensen, S. G.; Juul, R. I.; Nielsen, M. M.; Pedersen, J. S.
10.1101/2021.10.27.465848 — cancer biology — Posted on 2021-10-28
397 Patient-derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma
Groenewoud, A.; Yin, J.; Gelmi, M. C.; Alsafadi, S.; Nemati, F.; Decaudin, D.; Roman-Roman, S.; Kalirai, H.; Coupland, S. E.; Jochemsen, A. G.; Jager, M. J.; Snaar-Jagalska, E.
10.1101/2021.10.26.465874 — cancer biology — Posted on 2021-10-28
398 Structure Insight into Photosystem I Octamer from Cyanobacteria
Chen, M.; He, Y.; Liu, D.; Tian, L.; Xu, P.; Liu, X.; Pan, Y.; He, J.; ZHANG, Y.
10.1101/2021.10.27.465648 — biophysics — Posted on 2021-10-28
399 Spatial Probabilistic Mapping of Metabolite Ensembles in Mass Spectrometry Imaging
Abu Sammour, D.; Cairns, J. L.; Boskamp, T.; Guevara, C. R.; Panitz, V.; Sadik, A.; Cordes, J.; Marsching, C.; Friedrich, M.; Platten, M.; Wolf, I.; von Deimling, A.; Opitz, C. A.; Wick, W.; Hopf, C.
10.1101/2021.10.27.466114 — bioinformatics — Posted on 2021-10-28
401 PepSeA: Peptide Sequence Alignment and Visualization Tools to Enable Lead Optimization
Baylon, J. L.; Ursu, O.; Muzdalo, A.; Wassermann, A. M.; Adams, G. L.; Spale, M.; Mejzlik, P.; Gromek, A.; Pisarenko, V.; Hancharyk, D.; Jenkins, E.; Bednar, D.; Chang, C.; Clarova, K.; Glick, M.; Bitton, D. A.
10.1101/2021.10.26.465927 — bioinformatics — Posted on 2021-10-28
405 Electro-mechanical transfection for non-viral primary immune cell engineering
Sido, J. M.; Hemphill, J. B.; McCormack, R. N.; Beighley, R. D.; Grant, B. F.; Buie, C. R.; Garcia, P. A.
10.1101/2021.10.26.465897 — bioengineering — Posted on 2021-10-28
407 Benchmarking phasing software with a whole-genome sequenced cattle pedigree
Oget-Ebrad, C.; Kadri, N. K.; Costa Monteiro Moreira, G.; Karim, L.; Coppieters, W.; Georges, M.; Druet, T.
10.1101/2021.10.27.466052 — genomics — Posted on 2021-10-28
408 Regulation of defective mitochondrial DNA accumulation and transmission in C. elegans by the programmed cell death and aging pathways
Flowers, S. E.; Kothari, R.; Torres Cleuren, Y. N.; Alcorn, M. R.; Ewe, C. K.; Alok, G.; Joshi, P. M.; Rothman, J. H.
10.1101/2021.10.27.466108 — genetics — Posted on 2021-10-28
409 Formation and recycling of an active epigenetic mark mediated by cell cycle-specific RNAs
Tenen, D. G.; Espinosa Angarica, V.; Kappei, D.; Tenen, D.; Monteleone ., E.; Coffey, R.; Ummarino, S.; Tirado-Magallanes, R.; Wanet, A.; Bassal, M.; Trinh, B. L.; Sheen, M. R.; Di Ruscio, A.; Benoukraf, T.; Crane-Robinson, C.; Budnik, B.; Zhang, H.; Poli, V.; Zhang, Y.; Liu, Y.; Ebralidze, A. K.
10.1101/2021.10.27.466094 — genetics — Posted on 2021-10-28
410 H3K9me1/2 methylation limits the lifespan of C. elegans
Guang, S.; Huang, M.; Hong, M.; Zhu, C.; Chen, D.; Chen, X.; Feng, X.
10.1101/2021.10.27.466082 — genetics — Posted on 2021-10-28
411 A decade of stability for wMel Wolbachia in natural Aedes aegypti populations
Ross, P. A.; Robinson, K. L.; Yang, Q.; Callahan, A. G.; Schmidt, T. L.; Axford, J. K.; Coquilleau, M. P.; Staunton, K. M.; Townsend, M.; Ritchie, S. A.; Lau, M.-J.; Gu, X.; Hoffmann, A. A.
10.1101/2021.10.27.466190 — evolutionary biology — Posted on 2021-10-28
413 Comparative analysis of zooplankton diversity in freshwaters: What can we gain from metagenomic analysis?
Monchamp, M.-E.; Walsh, D. A.; Garner, R.; Kraemer, S.; Beisner, B. E.; Cristescu, M. E.; Gregory-Eaves, I.
10.1101/2021.10.27.465999 — ecology — Posted on 2021-10-28
415 Warming in the land of the midnight sun: breeding birds may suffer greater heat stress at high- vs low-Arctic sites
O'Connor, R. S.; Le Pogam, A.; Young, K. G.; Love, O. P.; Cox, C. J.; Roy, G.; Robitaille, F.; Elliott, K. H.; Hargreaves, A. L.; Choy, E. S.; Gilchrist, H. G.; Berteaux, D.; Tam, A.; Vézina, F.
10.1101/2021.10.26.465986 — ecology — Posted on 2021-10-28
417 Fruit colour and range size interact to influence diversification
Hill, A. P.; Torres Jimenez, M. F.; Chazot, N.; Cassia-Silva, C.; Faurby, S.; Bacon, C. D.
10.1101/2021.10.26.465838 — ecology — Posted on 2021-10-28
418 Evolutionarily divergent mTOR remodels the translatome to drive rapid wound closure and regeneration
Zhulyn, O.; Rosenblatt, H. D.; Shokat, L.; Dai, S. A.; Kuzuoglu-Öztürk, D.; Zhang, Z.; Ruggero, D.; Shokat, K.; Barna, M.
10.1101/2021.10.28.465024 — developmental biology — Posted on 2021-10-28
420 The Ribb-osome: Ribbon boosts ribosomal protein gene expression to coordinate organ form and function
Loganathan, R.; Levings, D. C.; Kim, J. H.; Wells, M. B.; Chiu, H.; Wu, Y.; Slattery, M.; Andrew, D. J.
10.1101/2021.10.27.466115 — developmental biology — Posted on 2021-10-28
421 Spd-2 Gene Duplication Suggests Cell-Type Specific Assembly Mechanisms of Pericentriolar Material
O'Neill, R. S.; Sodeinde, A.; Welsh, F. C.; Galletta, B. J.; Fagerstrom, C. J.; Rusan, N. M.
10.1101/2021.10.27.466145 — cell biology — Posted on 2021-10-28
423 Jaagsiekte sheep retrovirus infection induces changes in microRNA expression in the ovine lung
Contreras Garcia, M.; Karagianni, A. E.; Vasoya, D.; Jayaraman, S.; Lin, Y.-T.; Wood, A. R.; Dagleish, M.; Cousens, C.; Watson, M.; Grey, F.; Griffiths, D. J.
10.1101/2021.10.27.466207 — microbiology — Posted on 2021-10-28
426 Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation
Chen, X.; Sunkel, B.; Wang, M.; Kang, S.; Wang, T.; Gnanaprakasam, J. R.; Liu, L.; Cassel, T. A.; Scott, D. A.; Munoz-Cabello, A. M.; Lopez-Barneo, J.; Yang, J.; Lane, A. N.; Xin, G.; Stanton, B.; Fan, T. W.- M.; Wang, R.
10.1101/2021.10.26.465727 — immunology — Posted on 2021-10-28
427 Single-cell RNA sequencing unveils intestinal eosinophil development and specialization
Gurtner, A.; Borrelli, C.; Nunez, N. G.; Gonzalez-Perez, I.; Crepaz, D.; Handler, K.; Valenta, T.; Basler, K.; Becher, B.; Moor, A. E.; Arnold, I. C.
10.1101/2021.10.27.466053 — immunology — Posted on 2021-10-28
428 Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis
Kenney, A. D.; Aron, S. L.; Gilbert, C.; Kumar, N.; Chen, P.; Eddy, A.; Zhang, L.; Zani, A.; Vargas-Maldonado, N.; Speaks, S.; Kawahara, J.; Denz, P. J.; Dorn, L.; Accornero, F.; Ma, J.; Zhu, H.; Rajaram, M. V. S.; Cai, C.; Langlois, R. A.; Yount, J. S.
10.1101/2021.10.27.466128 — immunology — Posted on 2021-10-28
429 Dendritic cell ICAM-1 strengthens immune synapses but is dispensable for effector and memory responses
Sapoznikov, A.; Kozlovski, S.; Feigelson, S. W.; Davidzohn, N.; Wigoda, N.; Feldmesser, E.; Petrovich-Kopitman, E.; Grafen, A.; Biton, M.; Alon, R.
10.1101/2021.10.27.466043 — immunology — Posted on 2021-10-28
431 Chronic stroke sensorimotor impairment is related to smaller hippocampal volumes: An ENIGMA analysis
Zavaliangos-Petropulu, A.; Lo, B.; Donnelly, M. R.; Schweighofer, N.; Lohse, K.; Jahanshad, N.; Barisano, G.; Banaj, N.; Borich, M. R.; Boyd, L. A.; Buetefisch, C. M.; Byblow, W. D.; Cassidy, J. M.; Charalambous, C. C.; Conforto, A. B.; DiCarlo, J. A.; Dula, A. N.; Egorova-Brumley, N.; Etherton, M. R.; Feng, W.; Fercho, K. A.; Geranmayeh, F.; Hanlon, C. A.; Hayward, K. S.; Hordacre, B.; Kautz, S. A.; Khlif, M. S.; Kim, H.; Kuceyeski, A.; Lin, D. J.; Lotze, M.; Liu, J.; MacIntosh, B. J.; Margetis, J. L.; Piras, F.; Ramos-Murguialday, A.; Revill, K. P.; Roberts, P. S.; Robertson, A. D.; Schambra
10.1101/2021.10.26.465924 — neuroscience — Posted on 2021-10-28
434 A Riemannian approach to predicting brain function from the structural connectome
Benkarim, O.; Paquola, C.; Park, B.-y.; Royer, J.; Rodriguez-Cruces, R.; Vos de Wael, R.; Misic, B.; Piella, G.; Bernhardt, B.
10.1101/2021.10.27.465906 — neuroscience — Posted on 2021-10-28
436 Pharmacological impacts on schizophrenia functional analysis: a postmortem proteome study.
Shukla, R.; Alnafisah, R. S.; Reigle, J.; O'Donovan, S. M.; Funk, A. J.; Meller, J. M.; McCullumsmith, R. E.
10.1101/2021.10.26.465949 — neuroscience — Posted on 2021-10-28
437 A Locus Coeruleus- dorsal CA1 dopaminergic circuit modulates memory linking
Chowdhury, A.; Luchetti, A.; Fernandes, G.; Filho, D. A.; Kastellakis, G.; Tzilivaki, A.; Ramirez, E. M.; Tran, M. Y.; Poirazi, P.; Silva, A. J.
10.1101/2021.10.27.466138 — neuroscience — Posted on 2021-10-28
440 Long-term stability of neural activity in the motor system
Jensen, K. T.; Harpaz, N. K.; Dhawale, A. K.; Wolff, S. B. E.; Ölveczky, B.
10.1101/2021.10.27.465945 — neuroscience — Posted on 2021-10-28
441 Transcriptomic profiling of sex-specific olfactory neurons reveals subset-specific receptor expression in C. elegans
Reilly, D. K.; Schwarz, E. M.; Muirhead, C. S.; Robidoux, A. N.; Antoscheckin, I.; Narayan, A.; Doma, M.; Sternberg, P. W.; Srinivasan, J.
10.1101/2021.10.26.465928 — neuroscience — Posted on 2021-10-28
442 Differential Vulnerability of Anterior Cingulate Cortex Cell-Types to Diseases and Drugs
Shukla, R.; Smail, M. A.; Chandrasena, S. S.; Zhang, X.; Reddy, V.; Kelley, C.; Herman, J.; Sherif, M.; McCullumsmith, R. E.
10.1101/2021.10.26.465972 — neuroscience — Posted on 2021-10-28
444 SCS313 Serrano, a big trefoil selected for flowering ability and seed production
Rocha, D. J. A.; Cordova, U. A.; Flaresso, J.; Stradiotto, J.; Dalla-Costa, M.
10.1101/2021.10.26.465940 — plant biology — Posted on 2021-10-28
446 CaPti1/CaERF4 module positively regulates pepper resistance to bacterial wilt disease through coupling enhanced immunity and dehydration tolerance
Lanping, S.; Xia, L.; Yahong, W.; Hanyang, C.; Kaisheng, L.; Baixue, X.; Hussain, A.; Guan, D.; Shuilin, H.; Zhiqin, L.
10.1101/2021.10.26.465959 — physiology — Posted on 2021-10-28
447 The hormone Fibroblast Growth Factor 19 stimulates water intake
Ursic-Bedoya, J.; Chavey, C.; Meunier, L.; Desandre, G.; Dupuy, A.-M.; Gonzalez-Dopeso Reyes, I.; Tordjmann, T.; Assenat, E.; Hibner, U.; Gregoire, D.
10.1101/2021.10.26.466031 — physiology — Posted on 2021-10-28
448 Estimating the Inter- and Intra-Rater Reliability for NASH Fibrosis Staging in the Presence of Bridge Ordinal Ratings with Hierarchical Bridge Category Models
Levy, J.; Bobak, C.; Azizgolshani, N.; Liu, X.; Ren, B.; Lisovsky, M.; Suriawinata, A.; Christensen, B.; O'Malley, J.; Vaickus, L.
10.1101/2021.10.27.466144 — pathology — Posted on 2021-10-28
449 Cancer/Testis genes are predictive of breast tumor subtypes
Laisne, M.; Benlarama, S.; Nicolas, A.; Djerroudi, L.; Gupta, N.; Daher, D.; Ferry, L.; Kirsh, O.; Philippe, C.; Okada, Y.; Cristofari, G.; Meseure, D.; Vincent-Salomon, A.; Ginestier, C.; Defossez, P.-A.
10.1101/2021.10.27.465656 — cancer biology — Posted on 2021-10-28
455 Cryo-electron microscopy structure of the H3-H4 octasome without histones H2A and H2B
Nozawa, K.; Takizawa, Y.; Pierrakeas, L.; Saikusa, K.; Akashi, S.; Luk, E.; Kurumizaka, H.
10.1101/2021.10.27.466091 — biochemistry — Posted on 2021-10-28
458 Single-cell profiling of transcriptome and histone modifications with EpiDamID
Rang, F. J.; de Luca, K. L.; de Vries, S. S.; Valdes-Quezada, C.; Boele, E.; Nguyen, P. D.; Guerreiro, I.; Sato, Y.; Kimura, H.; Bakkers, J.; Kind, J.
10.1101/2021.10.26.465688 — genomics — Posted on 2021-10-28
459 PHB3 Regulates Lateral Root Primordia Formation via NO-mediated Degradation of AUX/IAAs
Wang, Y.; Li, S.; Li, Q.; Tian, X.; Mu, L.; Ji, M.; Wang, X.; Li, N.; Liu, F.; Shu, J.; Crawford, N. M.
10.1101/2021.10.28.466218 — developmental biology — Posted on 2021-10-28
462 Clonal gametogenesis is triggered by intrinsic stimuli in the hybrids germ cells but is dependent on sex differentiation
Tichopad, T.; Franek, R.; Kastankova, M. D.; Dedukh, D.; Marta, A.; Halacka, K.; Steinbach, C.; Janko, K.; Psenicka, M.
10.1101/2021.10.27.466081 — developmental biology — Posted on 2021-10-28
463 Map7D2 and Map7D1 facilitate MT stabilization through distinct mechanisms to control cell motility and neurite outgrowth
Kikuchi, K.; Sakamoto, Y.; Uezu, A.; Yamamoto, H.; Ishiguro, K.-i.; Shimamura, K.; Saito, T.; Hisanaga, S.-i.; Nakanishi, H.
10.1101/2021.10.27.466197 — cell biology — Posted on 2021-10-28
464 IntAct: a non-disruptive internal tagging strategy to study actin isoform organization and function
van Zwam, M. C.; Bosman, W.; van Straaten, W.; Weijers, S.; Seta, E.; Joosten, B.; van den Dries, K.
10.1101/2021.10.25.465733 — cell biology — Posted on 2021-10-28
465 Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors.
Burton, J.; Siller-Farfan, J. A.; Pettmann, J.; Salzer, B.; Kutuzov, M.; van der Merwe, P. A.; Dushek, O.
10.1101/2021.10.26.465853 — immunology — Posted on 2021-10-28
467 Parallel functional subnetworks embedded in the macaque face patch system
Park, S. H.; Koyano, K. W.; Russ, B. E.; Waidmann, E. N.; McMahon, D. B. T.; Leopold, D. A.
10.1101/2021.10.25.465775 — neuroscience — Posted on 2021-10-28
468 Altered circadian rhythms and sleep in a new Angelman Syndrome mouse model
Shi, S.; Mahoney, C.; Houdek, P.; Zhao, W.; Anderson, M.; Zhuo, X.; Beaudet, A.; Sumova, A.; Scammell, T.; Johnson, C. H.
10.1101/2021.10.26.465956 — neuroscience — Posted on 2021-10-28
469 PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery
Koc, S.; Lloyd, M. W.; Grover, J.; Seepo, S.; Lakshmi Subramanian, S.; Ray, M.; Frech, C.; DiGiovanna, J.; Webster, P.; Neuhauser, S.; Srivastava, A.; Yi Woo, X.; Sanderson, B. J.; White, B.; Lott, P.; PDXNet Consortium, ; Evrard, Y. A.; Wallace, T. A.; Moscow, J. A.; Doroshow, J. H.; Mitsiades, N.; Kaochar, S.; Pan, C.-x.; Chen, M. S.; Carvajal-Carmona, L.; Welm, A. L.; Welm, B. E.; Lewis, M. T.; Govindan, R.; Ding, L.; Li, S.; Herlyn, M.; Davies, M.; Roth, J.; Meric-Bernstam, F.; Robinson, P. N.; Bult, C. J.; Davis-Dusenbery, B.; Dean, D. A.; Chuang, J. H.
10.1101/2021.10.15.464537 — cancer biology — Posted on 2021-10-28
470 Ligand-induced transmembrane conformational coupling in monomeric EGFR
Srinivasan, S.; Regmi, R.; Lin, X.; Dreyer, C. A.; Chen, X.; Quinn, S. D.; He, W.; Carraway, K. L.; Coleman, M. A.; Zhang, B.; Schlau-Cohen, G. S.
10.1101/2021.10.28.466294 — biophysics — Posted on 2021-10-28
472 On the prediction of human intelligence from neuroimaging: A systematic review of methods and reporting
Hebling Vieira, B.; Pamplona, G. S. P.; Fachinello, K.; Kamensek Silva, A.; Foss, M. P.; Garrido Salmon, C. E.
10.1101/2021.10.19.462649 — neuroscience — Posted on 2021-10-28
473 A candidate causal variant underlying both enhanced cognitive performance and increased risk of bipolar disorder
Shen, S. Q.; Kim-Han, J. S.; Cheng, L.; Xu, D.; Gokcumen, O.; Hughes, A. E.; Myers, C. A.; Corbo, J. C.
10.1101/580258 — genetics — Posted on 2021-10-28
476 NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses
Leal, T. P.; Furlan, V. C.; Gouveia, M. H.; Duarte, J. M. S.; Fonseca, P. A.; Tou, R.; Scliar, M. O.; Araujo, G. S.; Zolini, C.; Peixoto, M. G. C. D.; Carvalho, M. R. S.; Lima-Costa, M. F.; Gilman, R. H.; Tarazona-Santos, E.; Rodrigues, M. R.
10.1101/2021.10.21.465343 — bioinformatics — Posted on 2021-10-28
482 NON-SPECIFIC EFFECTS OF A CINNAMATE-4-HYDROXYLASE INHIBITOR ON AUXIN HOMEOSTASIS
El Houari, I.; Klima, P.; Baekelandt, A.; Staswick, P.; Uzunova, V.; del Genio, C. I.; Steenackers, W.; Dobrev, P. I.; Novak, O.; Napier, R. M.; Petrasek, J.; Inze, D.; Boerjan, W.; Vanholme, B.
10.1101/2021.10.27.466161 — plant biology — Posted on 2021-10-28
483 Universal features shaping organelle gene retention
Giannakis, K.; Arrowsmith, S. J.; Richards, L.; Gasparini, S.; Chustecki, J. M.; Royrvik, E. C.; Johnston, I. G.
10.1101/2021.10.27.465964 — evolutionary biology — Posted on 2021-10-28
484 TEMPO: A system to sequentially label and genetically manipulate vertebrate cell lineages
Espinosa-Medina, I.; Feliciano, D.; Belmonte-Mateos, C.; Garcia-Marques, J.; Foster, B.; Miyares, R. L.; Pujades, C.; Koyama, M.; Lee, T.
10.1101/2021.10.27.466134 — developmental biology — Posted on 2021-10-28
486 Appropriate tension sensitivity of α-catenin ensures rounding morphogenesis of epithelial spheroids
Nishimura, R.; Kato, K.; Saida, M.; Kamei, Y.; Takeda, M.; Miyoshi, H.; Yamagata, Y.; Amano, Y.; Yonemura, S.
10.1101/2021.10.27.466008 — cell biology — Posted on 2021-10-28
488 Actively growing cells are the predominant persisters in exponential phase of Escherichia coli
Umetani, M.; Fujisawa, M.; Okura, R.; Nozoe, T.; Suenaga, S.; Nakaoka, H.; Kussell, E.; Wakamoto, Y.
10.1101/2021.10.28.466227 — microbiology — Posted on 2021-10-28
491 Impact of protein conformational diversity on AlphaFold predictions
Saldano, T.; Escobedo, N.; Marchetti, J.; Zea, D. J.; Mac Donagh, J.; Velez Rueda, A. J.; Gonik, E.; Garcia, A. M.; Novomisky Nechcoff, J.; Salas, M.; Peters, T.; Demitroff, N.; Fernandez Alberti, S.; Palopoli, N.; Fornasari, M. S.; Parisi, G.
10.1101/2021.10.27.466189 — bioinformatics — Posted on 2021-10-28
494 Development of ultrafast camera-based imaging of single fluorescent molecules and live-cell PALM
Fujiwara, T. K.; Takeuchi, S.; Kalay, Z.; Nagai, Y.; Tsunoyama, T. A.; Kalkbrenner, T.; Iwasawa, K.; Ritchie, K. P.; Suzuki, K. G. N.; Kusumi, A.
10.1101/2021.10.26.465864 — cell biology — Posted on 2021-10-28
495 TRF1 poly(ADP-ribosyl)ation by PARP1 allows proper telomere replication through helicase recruitment in non-ALT cells
Dello Stritto, A.; Maresca, C.; D'Angelo, C.; Petti, E.; Vertecchi, E.; Pompili, L.; Berardinelli, F.; Sgura, A.; Antoccia, A.; Graziani, G.; Biroccio, A.; Salvati, E.
10.1101/2021.10.27.466083 — molecular biology — Posted on 2021-10-28
496 A hyper-immunogenic and slow-growing fungal strain induces a murine granulomatous response to cryptococcal infection
Telzrow, C. L.; Esher Righi, S.; Castro-Lopez, N.; Campuzano, A.; Brooks, J. T.; Carney, J.; Wormley, F. L.; Alspaugh, J. A.
10.1101/2021.10.26.466037 — microbiology — Posted on 2021-10-28
497 DEAD-box RNA helicase 18 disrupts IRF3-binding to the interferon-β promoter
Xiao, S.; Xiao, X.; Wang, M.; Zhao, W.; Fang, P.; Zhou, Y.; Wang, D.; Fang, L.
10.1101/2021.10.26.465893 — immunology — Posted on 2021-10-28
499 Focal adhesion membrane is dotted with protein islands and partitioned for molecular hop diffusion
Fujiwara, T. K.; Takeuchi, S.; Kalay, Z.; Nagai, Y.; Tsunoyama, T. A.; Kalkbrenner, T.; Chen, L. H.; Shibata, A. C. E.; Iwasawa, K.; Ritchie, K. P.; Suzuki, K. G. N.; Kusumi, A.
10.1101/2021.10.26.465868 — cell biology — Posted on 2021-10-28
504 A transcriptomic axis predicts state modulation of cortical interneurons
Bugeon, S.; Duffield, J.; Dipoppa, M.; Ritoux, A.; Prankerd, I.; Nicoloutsopoulos, D.; Orme, D.; Shinn, M.; Peng, H.; Forrest, H.; Viduolyte, A.; Bai Reddy, C.; Isogai, Y.; Carandini, M.; Harris, K. D.
10.1101/2021.10.24.465600 — neuroscience — Posted on 2021-10-28
508 Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles
Sitarska, E.; Dias Almeida, S.; Beckwith, M.; Stopp, J.; Schwab, Y.; Sixt, M.; Kreshuk, A.; Erzberger, A.; Diz-Munoz, A.
10.1101/2021.03.26.437199 — cell biology — Posted on 2021-10-28
513 Activation of Npas1-neurons in the Ventral Pallidum Mediates Stress Susceptibility
Morais-Silva, G.; Nam, H.; Campbell, R.; Basu, M.; Pagliusi, M.; Fox, M. E.; Chan, S.; Iniguez, S. D.; Ament, S. A.; Marin, M. T.; Lobo, M. K.
10.1101/2021.10.27.466188 — neuroscience — Posted on 2021-10-28
515 Left angular gyrus disconnection impairs multiplication fact retrieval
Smaczny, S.; Sperber, C.; Jung, S.; Moeller, K.; Karnath, H.-O.; Klein, E.
10.1101/2021.10.27.465904 — neuroscience — Posted on 2021-10-28
517 Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes
Xie, F.; Armand, E. J.; Yao, Z.; Liu, H.; Bartlett, A.; Behrens, M. M.; Li, Y. E.; Lucero, J. D.; Luo, C.; Nery, J. R.; Pinto-Duarte, A.; Poirion, O.; Preissl, S.; Rivkin, A. C.; Tasic, B.; Zeng, H.; Ren, B.; Ecker, J. R.; Mukamel, E. A.
10.1101/2021.10.25.465795 — bioinformatics — Posted on 2021-10-28
518 Bioinformatic and mechanistic analysis of the palmerolide PKS-NRPS biosynthetic pathway from the microbiome of an Antarctic ascidian
Avalon, N. E.; Murray, A. E.; Daligault, H. E.; Lo, C.-C.; Dichosa, A. E. K.; Davenport, K. W.; Chain, P. S. G.; Baker, B. J.
10.1101/2021.04.05.438531 — biochemistry — Posted on 2021-10-27
520 MLF2 modulates phase separated nuclear envelope condensates that provoke dual proteotoxicity
Prophet, S. M.; Rampello, A. J.; Niescier, R. F.; Shaw, J. E.; Koleske, A. J.; Schlieker, C.
10.1101/2021.10.26.465916 — cell biology — Posted on 2021-10-27
521 Artificial intelligence reveals nuclear pore complexity
Mosalaganti, S.; Obarska-Kosinska, A.; Siggel, M.; Turonova, B.; Zimmerli, C. E.; Buczak, K.; Schmidt, F.; Margiotta, E.; Mackmull, M.; Hagen, W.; Hummer, G.; Beck, M.; Kosinski, J.
10.1101/2021.10.26.465776 — molecular biology — Posted on 2021-10-27
524 Absolute measurement of cellular activities using photochromic single-fluorophore biosensors
Gielen, V.; Mönkemöller, V.; Bierbuesse, F.; Bourges, A. C.; Shen, Y.; Hofkens, J.; Vanden Berghe, P.; Campbell, R. E.; Moeyaert, B.; Dedecker, P.
10.1101/2020.10.29.360214 — biophysics — Posted on 2021-10-27
526 Molecular basis for gating of cardiac ryanodine receptor: underlying mechanisms for gain- and loss-of function mutations
Kobayashi, T.; Tsutsumi, A.; Kurebayashi, N.; Saito, K.; Kodama, M.; Sakurai, T.; Kikkawa, M.; Murayama, T.; Ogawa, H.
10.1101/2020.11.30.401026 — biochemistry — Posted on 2021-10-27
528 An orthologous gene coevolution network provides insight into eukaryotic cellular and genomic structure and function
Steenwyk, J. L.; Phillips, M. A.; Yang, F.; Date, S. S.; Graham, T.; berman, j.; Hittinger, C. T.; Rokas, A.
10.1101/2021.07.09.451830 — evolutionary biology — Posted on 2021-10-27
531 ADNKA overcomes SARS-CoV2-mediated NK cell inhibition through non-spike antibodies
Fielding, C. A.; Sabberwal, P.; Williamson, J. C.; Greenwood, E. J.; Crozier, E.; Zelek, W.; Seow, J.; Graham, C.; Huettner, I.; Edgeworth, J.; Morgan, B. P.; Ladell, K.; Eberl, M.; Humphreys, I. R.; Merrick, B.; Doores, K. J.; Wilson, S. J.; Lehner, P. J.; Wang, E.; Stanton, R. J.
10.1101/2021.04.06.438630 — immunology — Posted on 2021-10-27
532 Relationship between systolic blood pressure and decision-making during emotional processing
Betka, S. J. A.; Watson, D.; Garfinkel, S. N.; Pfeifer, G.; Sequeira, H.; Duka, D.; Critchley, H.
10.1101/2021.10.22.465429 — neuroscience — Posted on 2021-10-27
533 Hi-C Resolution Enhancement with Genome Sequence Data
Kriukov, D.; Koritskiy, N.; Kozlovskii, I.; Zaretckii, M.; Bazarevich, M.; Zybin, M.; Khrameeva, E.
10.1101/2021.10.25.465745 — systems biology — Posted on 2021-10-27
539 de novo variant calling identifies cancer mutation profiles in the 1000 Genomes Project
Ng, J. K.; Vats, P.; Fritz-Waters, E.; Sarkar, S.; Sams, E. I.; Padhi, E. M.; Payne, Z. L.; Leonard, S.; West, M. A.; Prince, C.; Trani, L.; Jansen, M.; Vacek, G.; Samadi, M.; Harkins, T. T.; Pohl, C.; Turner, T. N.
10.1101/2021.05.27.445979 — genomics — Posted on 2021-10-27
540 Comprehensive evaluation of human brain gene expression deconvolution methods
Sutton, G. J.; Poppe, D.; Simmons, R. K.; Walsh, K.; Nawaz, U.; Lister, R.; Gagnon-Bartsch, J.; Voineagu, I.
10.1101/2020.06.01.126839 — genetics — Posted on 2021-10-27
544 Yolk sac-derived bipotent endothelial-macrophage progenitor cells are a self-renewing tissue-resident source of inflammation and neovascularization postnatally
Williamson, A.; Toledo-Flores, D.; Liyanage, S.; Hassanshahi, M.; Dimasi, C.; Schwarz, N.; Fernando, S.; Salagaras, T.; Long, A.; Di Bartolo, B. A.; Kazenwadel, J.; Harvey, N. L.; Drummond, G. R.; Vinh, A.; Chandrakanthan, V.; Misra, A.; Tan, J. T. M.; Bonder, C. S.; Nicholls, S. J.; Bursill, C. A.; Psaltis, P. J.
10.1101/2021.10.18.464001 — cell biology — Posted on 2021-10-27
545 Molecular identification of rhizobacterial isolates from Prosopis limensis and their effect on the growth of Raphanus sativus under salt stress
Clavo, R. F.; Valladolid Suyon, E. A.; Reynoza Farronan, K. J.; Ortega, C. D. A.; Valdera, G. Z.; Garboggini, F. F.; Iglesias-Osores, S.; Carreno Farfan, C. R.
10.1101/2021.10.25.464584 — molecular biology — Posted on 2021-10-27
551 Isolation of quenched light-harvesting complex II trimers from Arabidopsis leaves with sustained photoprotection (qH)
Bru, P.; Steen, C. J.; Park, S.; Amstutz, C. L.; Sylak-Glassman, E. J.; Leuenberger, M.; Lam, L.; Longoni, F.; Fleming, G. R.; Niyogi, K. K.; Malnoë, A.
10.1101/2021.07.09.450705 — plant biology — Posted on 2021-10-27
556 The molecular chaperone DNAJB6 provides surveillance of FG-Nups and is required for interphase nuclear pore complex biogenesis
Kuiper, E. F. E.; Gallardo, P.; Bergsma, T.; Mari, M.; Musskopf, M. K.; Kuipers, J.; Giepmans, B.; Steen, A.; Veenhoff, L.; Kampinga, H. H.; Bergink, S.
10.1101/2021.10.26.465890 — molecular biology — Posted on 2021-10-27
557 Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling
Jansen, J.; van den Berge, B. T.; van den Broek, M.; Maas, R. J.; Willemsen, B.; Kuppe, C.; Reimer, K. C.; Giovanni, G. D.; Mooren, F.; Nlandu, Q.; Mudde, H.; Wetzels, R.; den Braanker, D.; Parr, N.; Nagai, J. S.; Drenic, V.; Gesteira Costa Filho, I.; Steenbergen, E.; Nijenhuis, T.; Endlich, N.; van de Kar, N. C.; Schneider, R.; Wetzels, J. F.; van der Vlag, J.; Kramann, R.; Schreuder, M. F.; Smeets, B.
10.1101/2021.10.27.466054 — molecular biology — Posted on 2021-10-27
560 DNA-dependent binding of nargenicin to DnaE1 inhibits replication in Mycobacterium tuberculosis
Chengalroyen, M. D.; Mason, M. K.; Borsellini, A.; Tassoni, R.; Abrahams, G. L.; Lynch, S.; Ahn, Y.-M.; Ambler, J.; Young, K.; Crowley, B. M.; Olsen, D. B.; Warner, D. F.; Barry, C. E.; Boshoff, H. I. M.; Lamers, M.; Mizrahi, V.
10.1101/2021.10.27.466036 — microbiology — Posted on 2021-10-27
563 Efficient Inference of Sensitivity to Electrical Stimulation from Intrinsic Electrical Properties of Primate Retinal Ganglion Cells
Madugula, S. S.; Grosberg, L. E.; Shah, N. P.; Kling, A.; Goglietino, A. R.; Hottowy, P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2021.10.22.465478 — neuroscience — Posted on 2021-10-27
564 An increase in surface hydrophobicity mediates chaperone activity in N-chlorinated proteins
Varatnitskaya, M.; Fasel, J.; Müller, A.; Lupilov, N.; Shi, Y.; Fuchs, K.; Krewing, M.; Jung, C.; Jacob, T.; Sitek, B.; Bandow, J. E.; Carroll, K. S.; Leichert, L. I.
10.1101/2021.10.26.465855 — biochemistry — Posted on 2021-10-27
566 Ultra-deep sequencing reveals no evidence of oncogenic mutations or enrichment by ex vivo CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells
Cromer, M. K.; Barsan, V. V.; Jaeger, E.; Wang, M.; Hampton, J. P.; Chen, F.; Kennedy, D.; Khrebtukova, I.; Granat, A.; Truong, T.; Porteus, M. H.
10.1101/2021.10.27.466166 — genetics — Posted on 2021-10-27
568 Artificial intelligence reveals nuclear pore complexity
Mosalaganti, S.; Obarska-Kosinska, A.; Siggel, M.; Turonova, B.; Zimmerli, C. E.; Buczak, K.; Schmidt, F.; Margiotta, E.; Mackmull, M.; Hagen, W.; Hummer, G.; Beck, M.; Kosinski, J.
10.1101/2021.10.26.465776 — molecular biology — Posted on 2021-10-27
569 Total parenteral nutrition drives glucose metabolism disorders by modulating gut microbiota and its metabolites
Sun, H.; Wang, P.; Maitiabula, G.; Zhang, L.; Yang, J.; Zhang, Y.; Gao, X.; Li, J.; Xue, B.; Li, C.; Wang, X.
10.1101/2021.10.26.466009 — microbiology — Posted on 2021-10-27
570 Structural and functional characterization of DdrC, a novel DNA damage-induced nucleoid associated protein involved in DNA compaction
Banneville, A.-S.; Bouthier de la Tour, C.; Hognon, C.; Colletier, J.-P.; Teulon, J.-M.; Le Roy, A.; Pellequer, J.-L.; Monari, A.; Dehez, F.; Confalonieri, F.; Servant, P.; Timmins, J.
10.1101/2021.10.27.466113 — microbiology — Posted on 2021-10-27
574 Predictability and parallelism in the contemporary evolution of hybrid genomes
Langdon, Q. K.; Powell, D. L.; Kim, B.; Banerjee, S. M.; Payne, C.; Dodge, T. O.; Moran, B.; Fascinetto-Zago, P.; Schumer, M.
10.1101/2021.07.06.451368 — evolutionary biology — Posted on 2021-10-27
576 In vivo reprogramming of murine host immune response genes following Leishmania major infection.
Venugopal, G.; Bird, J. T.; Washam, C. L.; Roys, H.; Bowlin, A.; Byrum, S. D.; Weinkopff, T.
10.1101/2021.10.05.463063 — immunology — Posted on 2021-10-27
577 The therapeutic and diagnostic potential of amyloid β oligomers (AβOs) selective antibodies to treat Alzheimer's disease
Viola, K. L.; Bicca, M. A.; Bebenek, A. M.; Kranz, D. L.; Nandwana, V.; Waters, E. A.; Haney, C. R.; Lee, M.; Gupta, A.; Brahmbhatt, Z.; Huang, W.; Chang, T.-T.; Peck, A.; Valdez, C.; Dravid, V. P.; Klein, W. L.
10.1101/2021.09.20.460817 — neuroscience — Posted on 2021-10-27
579 Titration of in-cellula affinities of protein-protein interactions
Cluet, D.; Vergier, B.; Levy, N.-P.; Dehau, L.; Thurman, A.; Amri, I.; Spichty, M.
10.1101/2020.04.27.063552 — biochemistry — Posted on 2021-10-27
582 The structurome of a Clostridium difficile phage and the remarkable accurate prediction of its novel phage receptor-binding protein
Dowah, A. S. A.; Xia, G.; Thanki, A. M.; Ali, A. A. K.; Shan, J.; Millard, A. D.; Petersen, B.; Sicheritz-Ponten, T.; Wallis, R.; Clokie, M. R. J.
10.1101/2021.07.05.451159 — molecular biology — Posted on 2021-10-27
586 A transcriptomic axis predicts state modulation of cortical interneurons
Bugeon, S.; Duffield, J.; Dipoppa, M.; Ritoux, A.; Prankerd, I.; Nicoloutsopoulos, D.; Orme, D.; Shinn, M.; Peng, H.; Forrest, H.; Viduolyte, A.; Bai Reddy, C.; Isogai, Y.; Carandini, M.; Harris, K. D.
10.1101/2021.10.24.465600 — neuroscience — Posted on 2021-10-27
589 The complex genetics of symbiotic extended phenotypes across environments in a model mutualism
Batstone, R. T.; Lindgren, H. K.; Allsup, C. M.; Goralka, L. A.; Riley, A. B.; Grillo, M. A.; Marshall-Colon, A.; Heath, K.
10.1101/2021.08.03.454976 — evolutionary biology — Posted on 2021-10-27
591 Tfap2b specifies an embryonic melanocyte stem cell population that retains adult multi-fate potential
Brombin, A.; Simpson, D. J.; Travnickova, J.; Brunsdon, H. R.; Zeng, Z.; Lu, Y.; Young, A. I. J.; Chandra, T.; Patton, E. E.
10.1101/2021.06.18.448859 — developmental biology — Posted on 2021-10-27
594 Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore sequencing
Begik, O.; Liu, H.; Delgado-Tejedor, A.; Kontur, C.; Giraldez, A. J.; Beaudoin, J.-D.; Mattick, J. S.; Novoa, E. M.
10.1101/2021.09.22.461331 — molecular biology — Posted on 2021-10-27
595 Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis
Dashti, Y.; Mohammadipanah, F.; Belousoff, M. J.; Vocat, A.; Zabala, D.; Fage, C. D.; Romero-Canelon, I.; Bunk, B.; Sproer, C.; Overmann, J.; Cole, S. T.; Challis, G. L.
10.1101/2021.10.24.465558 — microbiology — Posted on 2021-10-27
597 Multi-model Order ICA: A Data-driven Method for Evaluating Brain Functional Network Connectivity Within and Between Multiple Spatial Scales
Meng, X.; Iraji, A.; Fu, Z.; Kochunov, P.; Belger, A.; Ford, J.; McEwen, S.; Mathalon, D. H.; Mueller, B. A.; Pearlson, G. D.; Potkin, S. G.; Preda, A.; Turner, J.; van Erp, T. G. M.; Sui, J.; Calhoun, V.
10.1101/2021.10.24.465635 — neuroscience — Posted on 2021-10-27
599 Rhythmic clock gene expression in Atlantic salmon parr brain
Bolton, C.; Bekaert, M.; Eilertsen, M.; Helvik, J. V.; Migaud, H.
10.1101/2021.08.18.456820 — physiology — Posted on 2021-10-27
602 Does time matter in phylogeny? A perspective from the fossil record
Guenser, P.; Warnock, R. C. M.; Pett, W.; Donoghue, P. C. J.; Jarochowska, E.
10.1101/2021.06.11.445746 — paleontology — Posted on 2021-10-27
603 scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation
Raine, A.; Lundmark, A.; Annett, A.; Wiman, A.-C.; Cavalli, M.; Wadelius, C.; Bergin, C.; Nordlund, J.
10.1101/2021.10.14.464375 — genomics — Posted on 2021-10-27
605 Metformin increases tauroursodeoxycholic acid levels to improve insulin resistance in diet-induced obese mice
Zhang, Y.; Yang, C.; Liu, J.; He, D.; Zuo, J.; Yan, L.; Thring, R. W.; Wu, M.; Gao, Y.; Tong, H.
10.1101/2020.05.26.116715 — molecular biology — Posted on 2021-10-27
606 DiversityScanner: Robotic discovery of small invertebrates with machine learning methods
Wuehrl, L.; Pylatiuk, C.; Giersch, M.; Lapp, F.; von Rintelen, T.; Balke, M.; Schmidt, S.; Cerretti, P.; Meier, R.
10.1101/2021.05.17.444523 — zoology — Posted on 2021-10-27
607 Anatomic development of the upper airway during the first five years of life: A three-dimensional imaging study
Chuang, Y. J.; Hwang, S. J.; Buhr, K. A.; Miller, C. A.; Avey, G. D.; Story, B. H.; Vorperian, H. K.
10.1101/2021.10.26.465942 — developmental biology — Posted on 2021-10-26
610 Focal adhesion membrane is dotted with protein islands and partitioned for molecular hop diffusion
Fujiwara, T. K.; Takeuchi, S.; Kalay, Z.; Nagai, Y.; Tsunoyama, T. A.; Kalkbrenner, T.; Chen, L. H.; Shibata, A. C. E.; Iwasawa, K.; Ritchie, K. P.; Suzuki, K. G. N.; Kusumi, A.
10.1101/2021.10.26.465868 — cell biology — Posted on 2021-10-26
612 Development of ultrafast camera-based imaging of single fluorescent molecules and live-cell PALM
Fujiwara, T. K.; Takeuchi, S.; Kalay, Z.; Nagai, Y.; Tsunoyama, T. A.; Kalkbrenner, T.; Iwasawa, K.; Ritchie, K. P.; Suzuki, K. G. N.; Kusumi, A.
10.1101/2021.10.26.465864 — cell biology — Posted on 2021-10-26
613 Report of unexpected findings after cardiac stem cell injections in a preclinical model
van der Naald, M.; van den Broek, H. T.; Bemelmans, J. L.; Neef, K.; Bakker, M. H.; Dankers, P. Y.; Kraaijeveld, A. O.; Chamuleau, S. A.
10.1101/2021.10.26.465939 — cell biology — Posted on 2021-10-26
615 Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys
Pippin, J. W.; Kaverina, N.; Wang, Y.; Eng, D.; Zeng, Y.; Tran, U.; Loretz, C. J.; Chang, A.; O'Connor, C.; Bitzer, M.; Wessely, O.; Shankland, S. J.
10.1101/2021.10.26.466006 — cell biology — Posted on 2021-10-26
617 Sensory prediction errors increase coding efficiency in mouse visual cortex through gain amplification
Tang, M. F.; Kheradpezhouh, E.; Lee, C. C.; Dickinson, J. E.; Mattingley, J. B.; Arabzadeh, E.
10.1101/2021.10.26.466004 — neuroscience — Posted on 2021-10-26
623 Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics
Johri, S.; Bi, K.; Titchen, B. M.; Fu, J.; Conway, J.; Crowdis, J. P.; Volkes, N. I.; Fan, Z.; Fong, L.; Park, J.; Liu, D.; He, M. X.; Van Allen, E.
10.1101/2021.10.22.465130 — bioinformatics — Posted on 2021-10-26
625 Architecture of the linker-scaffold in the nuclear pore
Petrovic, S.; Samanta, D.; Perriches, T.; Bley, C. J.; Thierbach, K.; Brown, B.; Nie, S.; Mobbs, G. W.; Stevens, T. A.; Liu, X.; Hoelz, A.
10.1101/2021.10.26.465796 — biochemistry — Posted on 2021-10-26
626 Architecture of the cytoplasmic face of the nuclear pore
Bley, C. J.; Nie, S.; Mobbs, G.; Petrovic, S.; Gres, A.; Liu, X.; Mukherjee, S.; Harvey, S.; Huber, F. M.; Lin, D. H.; Brown, B.; Tang, A. W.; Rundlet, E. J.; Correia, A. R.; Chen, S.; Regmi, S. G.; Dasso, M.; Patke, A.; Palazzo, A. F.; Kossiakoff, A. A.; Hoelz, A.
10.1101/2021.10.26.465790 — biochemistry — Posted on 2021-10-26
627 Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin re-organization
Matthey-Doret, C.; Colp, M. J.; Escoll, P.; Thierry, A.; Curtis, B.; Sarrasin, M.; Gray, M. W.; Lang, B. F.; Archibald, J. M.; Buchrieser, C.; Koszul, R.
10.1101/2021.10.26.465878 — genomics — Posted on 2021-10-26
628 Mother centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
Wong, S.-S.; Wilmott, Z. M.; Saurya, S.; Zhou, F. Y.; Chau, K.-Y.; Goriely, A.; Raff, J.
10.1101/2021.10.26.465695 — cell biology — Posted on 2021-10-26
629 Dissecting gating mechanisms of Orai calcium channel paralogs using constitutively active Orai mutants that mimic STIM1-gated state
Augustynek, B.; Gyimesi, G.; Dernic, J.; Sallinger, M.; Albano, G.; Klesse, G. J.; Kandasamy, P.; Grabmayr, H.; Frischauf, I.; Fuster, D. G.; Peinelt, C.; Hediger, M. A.; Bhardwaj, R.
10.1101/2021.10.26.465861 — cell biology — Posted on 2021-10-26
630 The glutathione import system satisfies the Staphylococcus aureus nutrient sulfur requirement and promotes interspecies competition.
Lensmire, J. M.; Wischer, M. R.; Sosinski, L. M.; Ensink, E.; Dodson, J. P.; Shook, J. C.; Delekta, P. C.; Cooper, C. C.; Havlichek, D.; Mulks, M. H.; Lunt, S. Y.; Ravi, J.; Hammer, N. D.
10.1101/2021.10.26.465763 — microbiology — Posted on 2021-10-26
631 Diversity, function and evolution of marine microbe genomes
Chen, J.; Guo, Y.; Jia, Y.; Liu, G.; Li, D.; Xu, D.; Wang, B.; Zhou, L.; Peng, L.; Zhao, F.; Zhu, Y.; Sun, J.; Ye, C.; Wang, J.; Zhang, H.; Liu, S.; Seim, I.; Liu, X.; Xu, X.; Yang, H.; Consortium, G.; Kristiansen, K.; Fan, G.
10.1101/2021.10.26.465843 — microbiology — Posted on 2021-10-26
632 Fine-scale adaptations to environmental variation and growth strategies drive phyllosphere Methylobacterium diversity.
Leducq, J.-B.; Seyer-Lamontagne, E.; Condrain-Morel, D.; Bourret, G.; Sneddon, D.; Foster, J. A.; Marx, C. J.; Sullivan, J. M.; Shapiro, B. J.; Kembel, S. W.
10.1101/2021.06.04.447128 — microbiology — Posted on 2021-10-26
633 Cell wall damage reveals spatial flexibility in peptidoglycan synthesis and a non-redundant role for RodA in mycobacteria
Melzer, E. S.; Kado, T.; Garcia-Heredia, A.; Gupta, K. R.; Meniche, X.; Morita, Y. S.; Sassetti, C. M.; Rego, E. H. M.; Siegrist, M. S.
10.1101/2021.10.26.465981 — microbiology — Posted on 2021-10-26
634 Adenovirus-α-defensin complexes induce NLRP3-associated maturation of human phagocytes via TLR4 engagement
Eichholz, K.; Tran, H. T.; Cheneau, C.; Tran, T. T. P.; Paris, O.; Pugniere, M.; Kremer, E. J.
10.1101/2021.10.26.465098 — immunology — Posted on 2021-10-26
635 Excessive inflammatory and metabolic responses to acute SARS-CoV-2 infection are associated with a distinct gut microbiota composition
Albrich, W. C.; Ghosh, T. S.; Ahearn-Ford, S.; Mikaeloff, F.; Lunjani, N.; Forde, B.; Suh, N.; Kleger, G.-R.; Pietsch, U.; Frischknecht, M.; Garzoni, C.; Forlenza, R.; Horgan, M.; Sadlier, C.; Negro, T. R.; Pugin, J.; Wozniak, H.; Cerny, A.; Neogi, U.; O'Toole, P. W.; O'Mahony, L.
10.1101/2021.10.26.465865 — immunology — Posted on 2021-10-26
637 An innate immune activation state prior to vaccination predicts responsiveness to multiple vaccines
Fourati, S.; Tomalin, L. E.; Mule, M. P.; Chawla, D. G.; Gerritsen, B.; Rychkov, D.; Henrich, E.; Miller, H. E.; Hagan, T.; Diray-Arce, J.; Dunn, P.; The Human Immunology Project Consortium (HIPC), ; Levy, O.; Gottardo, R.; Sarwal, M.; Tsang, J. S.; Suarez-Farinas, M.; Pulendran, B.; Sekaly, R.-P.; Kleinstein, S. H.
10.1101/2021.09.26.461847 — systems biology — Posted on 2021-10-26
639 Ligand-induced unfolding mechanism of an RNA G-quadruplex
Haldar, S.; Zhang, Y.; Xia, Y.; Islam, B.; Liu, S.; Gervasio, F. L.; Mulholland, A. J.; Waller, Z.; Wei, D.; Haider, S.
10.1101/2021.10.26.465985 — biophysics — Posted on 2021-10-26
642 Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads
Ramiro, I. B. L.; Bjoern-Yoshimoto, W. E.; Imperial, J. S.; Gajewiak, J.; Watkins, M.; Taylor, D.; Resager, W.; Ueberheide, B.; Brauner-Osborne, H.; Whitby, F. G.; Hill, C. P.; Martin, L. F.; Patwardhan, A.; Concepcion, G. P.; Olivera, B. M.; Safavi-Hemami, H.
10.1101/2021.10.26.465842 — biochemistry — Posted on 2021-10-26
645 Extracellular loop 2 of G protein-coupled olfactory receptors is critical for odorant recognition
Yu, Y.; Pacalon, J.; Ma, Z.; Xu, L.; Belloir, C.; Topin, J.; Briand, L.; Golebiowski, J.; Cong, X.
10.1101/2021.10.26.465980 — molecular biology — Posted on 2021-10-26
647 Interaction Between Transcribing RNA Polymerase and Topoisomerase I Prevents R-loop Formation in E. coli
Sutormin, D.; Galivondzhyan, A.; Musharova, O.; Travin, D. Y.; Rusanova, A.; Obraztsova, K.; Borukhov, S.; Severinov, K.
10.1101/2021.10.26.465782 — molecular biology — Posted on 2021-10-26
648 Fungal auxin is a quorum-based modulator of blast disease severity
Dong, L.; Shen, Q.; Chen, C.-Y.; Shen, L.; Yang, F.; Naqvi, N. I.; Deng, Y. Z.
10.1101/2021.10.26.465851 — microbiology — Posted on 2021-10-26
649 Geological processes mediate a subsurface microbial loop in the deep biosphere
Gittins, D.; Desiage, P.-A.; Morrison, N.; Rattray, J. E.; Bhatnagar, S.; Chakraborty, A.; Zorz, J.; Horanszky, O.; Cramm, M. A.; Webb, J.; MacDonald, A.; Fowler, M.; Campbell, C.; Hubert, C. R.
10.1101/2021.10.26.465990 — microbiology — Posted on 2021-10-26
650 Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci
Lima, A. R.; Poubel, S. B.; Roson, J. N.; de Lima, L. P.; Costa-Silva, H. M.; Silva, H. G.; Goncalves, C.; Galante, P. A.; Holetz, F.; Motta, M. C.; Silber, A. M.; Elias, M. C.; da Cunha, J. P.
10.1101/2021.10.26.465934 — microbiology — Posted on 2021-10-26
653 Hepatitis C Virus Infects and Perturbs Liver Stem Cells
Meyers, N. L.; Ashuach, T.; Lyons, D. E.; Simoneau, C. R.; Erickson, A. L.; Nguyen, T. T.; Bouhaddou, M.; Khalid, M. M.; Taha, T. Y.; Natarajan, V.; Baron, J. L.; Neff, N.; Zanini, F.; Mahmoudi, T.; Quake, S. R.; Krogan, N. J.; Cooper, S. L.; McDevitt, T. C.; Yosef, N.; Ott, M.
10.1101/2021.10.26.465357 — microbiology — Posted on 2021-10-26
655 LILRB1 and LILRB2 expression in peripheral blood immune cells at 18 and 24 months of age in infants born from mothers with placental malaria
Dechavanne, C.; Nouatin, O.; Adamou, R.; Edslev, S.; Hansen, A.; Meurisse, F.; Sadissou, I.; Gbaguidi, E.; Milet, J.; Cottrell, G.; Gineau, L.; Sabbagh, A.; Massougbodji, A.; Moutairou, K.; Donadi, E. A.; Carosella, E.; Moreau, P.; Remarque, E.; Theisen, M.; Rouas-Freiss, N.; Garcia, A.; Favier, B.; Courtin, D.
10.1101/2021.10.26.465873 — immunology — Posted on 2021-10-26
659 Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers
Tao, Y.; Ma, X.; Laliotis, G. I.; Zuniga, A. G.; Palmer, D.; Toska, E.; Schwartz, R.; Lu, X.; Osmanbeyoglu, H. U.
10.1101/2021.09.07.459263 — bioinformatics — Posted on 2021-10-26
664 Transmission of Klebsiella strains and plasmids within and between Grey-headed flying fox colonies
Vezina, B.; Judd, L. M.; McDougall, F. K.; Boardman, W. S.; Power, M. L.; Hawkey, J.; Brisse, S.; Monk, J. M.; Holt, K. E.; Wyres, K. L.
10.1101/2021.10.25.465810 — microbiology — Posted on 2021-10-26
665 Clostridioides difficile infection increases circulating p-cresol levels and dysregulates brain dopamine metabolism: linking gut-brain axis to autism and other neurologic disorders?
A. Vinithakumari, A.; Padhi, P.; G. Hernandez, B.; Je-Han Lin, S.; Dunkerson-Kurzhumov, A.; Showman, L.; Breitzman, M.; Stokes, C.; Sulaiman, Y.; Tangudu, C.; Kuttappan, D. A.; Muyyarikkandy, M. S.; Phillips, G. J.; Anantharam, V.; Perera, A.; Sponseller, B.; Kanthasamy, A.; Mooyottu, S.
10.1101/2021.10.22.465382 — neuroscience — Posted on 2021-10-26
668 Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axis
Cikes, D.; Leutner, M.; Cronin, S. J. - F.; Novatchkova, M.; Pfleger, L.; Klepochova, R.; Rullman, E.; Gustafsson, T.; Hagelkrueys, A.; Krebs, M.; Kautzky-Willer, A.; Krssak, M.; Orthofer, M.; Penninger, J. M.
10.1101/2021.10.26.465828 — physiology — Posted on 2021-10-26
670 A Cytoskeletal Vortex Drives Phage Nucleus Rotation During Jumbo Phage Replication inE. coli
Birkholz, E. A.; Laughlin, T. G.; Suslov, S.; Armbruster, E.; Lee, J.; Wittmann, J.; Corbett, K. D.; Villa, E.; Pogliano, J.
10.1101/2021.10.25.465362 — microbiology — Posted on 2021-10-26
671 Structural snapshots of V/A-ATPase reveal a new paradigm for rotary catalysis
Kishikawa, J.-i.; Nakanishi, A.; Nakano, A.; Saeki, S.; Furuta, A.; Kato, T.; Mitsuoka, K.; Yokoyama, K.
10.1101/2021.10.26.465817 — biophysics — Posted on 2021-10-26
676 Tfap2b specifies an embryonic melanocyte stem cell population that retains adult multi-fate potential
Brombin, A.; Simpson, D. J.; Travnickova, J.; Brunsdon, H. R.; Zeng, Z.; Lu, Y.; Chandra, T.; Patton, E. E.; Young, A. I. J.
10.1101/2021.06.18.448859 — developmental biology — Posted on 2021-10-26
678 Quantitative Profiling of Adaptation to Cyclin E Overproduction
Limas, J. C.; Littlejohn, A. N.; House, A. M.; Kedziora, K. M.; Mouery, B. L.; Ma, B.; Fleifel, D.; Walens, A.; Aleman, M. M.; Dominguez, D.; Cook, J. G.
10.1101/2021.07.26.453751 — cell biology — Posted on 2021-10-26
680 Viral infection switches the balance between bacterial and eukaryotic recyclers of organic matter during algal blooms
Vincent, F.; Gralka, M.; Schleyer, G.; Schatz, D. J.; Cabrera-Brudau, M.; Kuhlisch, C.; Sichert, A.; Vidal-Melgosa, S.; Mayers, K.; Barak-Gavish, N.; Flores, M.; Masdeu-Navarro, M.; Egge, J. K.; Larsen, A.; Heheman, J.-H.; Marrase, C.; Simo, R.; Cordero, O. X.; Vardi, A.
10.1101/2021.10.25.465659 — microbiology — Posted on 2021-10-26
681 Functional and Structural Characterization of OXA-935, a Novel OXA-10-family β-lactamase from Pseudomonas aeruginosa
Pincus, N. B.; Rosas-Lemus, M.; Gatesy, S. W.; Shuvalova, L. A.; Brunzelle, J.; Minasov, G. A.; Satchell, K. J. F.; Lebrun-Corbin, M.; Ozer, E. A.; Hauser, A. R.; Bachta, K. E. R.
10.1101/2021.09.20.461173 — microbiology — Posted on 2021-10-26
684 Truncating Tau Reveals Different Pathophysiological Actions of Oligomers in Single Neurons
Hill, E.; Karikari, T. K.; Lantero-Rodriguez, J.; Zetterberg, H.; Blennow, K.; Richardson, M. J.; Wall, M. J.
10.1101/2021.05.13.443904 — neuroscience — Posted on 2021-10-26
685 Long-range connections mirror and link microarchitectural and cognitive hierarchies in the human brain
Wang, Y.; Royer, J.; Park, B.-y.; Vos de Wael, R.; Lariviere, S.; Tavakol, S.; Rodriguez-Cruces, R.; Paquola, C.; Hong, S.-J.; Margulies, D.; Smallwood, J.; Valk, S.; Evans, A.; Bernhardt, B. C.
10.1101/2021.10.25.465692 — neuroscience — Posted on 2021-10-26
688 KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
D'oto, A.; Fang, J.; Jin, H.; Xu, B.; Singh, S.; Mullasseril, A.; Jones, V.; Von Butler, X.; Cooke, B.; Hu, D.; Shohet, J.; Murphy, A.; Davidoff, A.; YANG, J.
10.1101/2020.07.02.184986 — cancer biology — Posted on 2021-10-26
690 An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease
Palanski, B. A.; Weng, N.; Zhang, L.; Hilmer, A. J.; Fall, L. A.; Swaminathan, K.; Jabri, B.; Sousa, C.; Fernandez-Becker, N. Q.; Khosla, C.; Elias, J. E.
10.1101/2021.03.17.435829 — biochemistry — Posted on 2021-10-26
692 Genome-wide association identifies candidate genes for drought tolerance in coast redwood and giant sequoia
De La Torre, A.; Sekhwal, M. K.; Puiu, D.; Salzberg, S.; Scott, A. D.; Allen, B.; Neale, D. B.; Chin, A.; Buckley, T. N.
10.1101/2021.10.25.465813 — genomics — Posted on 2021-10-26
694 The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membraneless granular phase separation
Lyonnais, S.; Sadiq, S. K.; Lorca-Oro, C.; Dufau, L.; Nieto-Marquez, S.; Escriba, T.; Gabrielli, N.; Tan, X.; Ouizougun-Oubari, M.; Okoronkwo, J.; Reboud-Ravaux, M.; Gatell, J. M.; Marquet, R.; Paillart, J.-C.; Meyerhans, A.; Tisne, C.; Gorelick, R. J.; Mirambeau, G.
10.1101/528638 — molecular biology — Posted on 2021-10-26
695 Nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants
Maeda, R.; Fujita, J.; Konishi, Y.; Kazuma, Y.; Yamazaki, H.; Anzai, I.; Yamaguchi, K.; Kasai, K.; Nagata, K.; Yamaoka, Y.; Miyakawa, K.; Ryo, A.; Shirakawa, K.; Makino, F.; Matsuura, Y.; Inoue, T.; Imura, A.; Namba, K.; Takaori-Kondo, A.
10.1101/2021.10.25.465714 — molecular biology — Posted on 2021-10-26
696 Vaccinia E5 is a major inhibitor of the DNA sensor cGAS
Yang, N.; Wang, Y.; Dai, P.; Li, T.; Zierhut, C.; Tan, A.; Zhang, T.; Pan, H.; Li, Z.; Ordureau, A.; Xiang, J. Z.; Hendrickson, R. C.; Funabiki, H.; Chen, Z.; Deng, L.
10.1101/2021.10.25.465197 — microbiology — Posted on 2021-10-26
697 Structure, receptor recognition and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein
Tortorici, M. A.; Walls, A. C.; Joshi, A.; Park, Y.-J.; Eguia, R. T.; Stevens-Ayers, T.; Boeckh, M. J.; Talenti, A.; Lanzavecchia, A.; Corti, D.; Bloom, J. D.; Veesler, D.
10.1101/2021.10.25.465646 — microbiology — Posted on 2021-10-26
698 Plasmodium sporozoites require the protein B9 to invade hepatocytes
Fernandes, P.; Loubens, M.; Marinach, C.; Coppee, R.; Grand, M.; Andre, T.-P.; Hamada, S.; Langlois, A.-C.; Briquet, S.; Bun, P.; Silvie, O.
10.1101/2021.10.25.465731 — microbiology — Posted on 2021-10-26
700 Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization
Richter, F. C.; Friedrich, M.; Pohin, M.; Alsaleh, G.; Guschina, I.; Wideman, S. K.; Johnson, E.; Borsa, M.; Piletic, K.; Hahn, P.; Schipper, H. S.; Edwards, C.; Powrie, F.; Simon, A. K.
10.1101/2021.10.25.465200 — immunology — Posted on 2021-10-26
701 Targeting the chemokine receptor CXCR4 with histamine analogue to reduce inflammation in juvenile arthritis: a proof of concept for COVID-19 therapeutic approach
Bekaddour, N.; Smith, N.; Beitz, B.; Llibre, A.; Dott, T.; Baudry, A.; Korganow, A.-S.; Nisole, S.; Mouy, R.; Breton, S.; Bader-Meunier, B.; Duffy, D.; Terrier, B.; Schneider, B.; Quartier, P.; Rodero, M.; Herbeuval, J.-P.
10.1101/2021.10.24.465080 — immunology — Posted on 2021-10-26
703 The kidney protects against sepsis by enhancing the systemic release of Uromodulin to stimulate macrophage function
LaFavers, K.; Hage, C.; Gaur, V.; Micanovic, R.; Hato, T.; Khan, S.; Winfree, S.; Doshi, S.; Moorthi, R.; Twigg, H.; Wu, X.-R.; Dagher, P.; Srour, E.; El-Achkar, T. M.
10.1101/2021.01.08.425960 — immunology — Posted on 2021-10-26
707 Subtype transcriptomic profiling of myeloid cells in Alzheimer Disease brain illustrates the diversity in active microglia phenotypes
Prater, K. E.; Green, K. J.; Smith, C.; Sun, W.; Chiou, K. L.; Heath, L. M.; Rose, S.; Shojaie, A.; Snyder-Mackler, N.; Keene, C. D.; Blue, E.; Young, J. E.; Logsdon, B.; Garden, G. A.; Jayadev, S.
10.1101/2021.10.25.465802 — neuroscience — Posted on 2021-10-26
709 A global timing mechanism regulates cell-type specific wiring programs
Jain, S.; Lin, Y.; Kurmangaliyev, Y. Z.; Valdes-Aleman, J.; LoCascio, S. A.; Mirshahidi, P.; Parrington, B.; Zipursky, S. L.
10.1101/2020.09.18.304410 — neuroscience — Posted on 2021-10-26
710 The social architecture of an in-depth cellular protein interactome
Michaelis, A. C.; Brunner, A.-D.; Zwiebel, M.; Meier, F.; Strauss, M. T.; Bludau, I.; Mann, M.
10.1101/2021.10.24.465633 — systems biology — Posted on 2021-10-26
713 Characterization of cardiac pacemaker activity in the primate lemur Microcebus murinus.
DiFrancesco, M. L.; Davaze, R.; Torre, E.; Mesirca, P.; Marrot, M.; Lautier, C.; Fontes, P.; Cuoq, J.; Fernandez, A.; Pifferi, F.; Mestre Frances, N.; Mangoni, M. E.; Torrente, A. G.
10.1101/2021.10.25.465774 — physiology — Posted on 2021-10-26
714 SERCA-mediated calcium uptake in the DBA/2J vs C57BL/10 mdx models of Duchenne muscular dystrophy
Cleverdon, R. E.; Whitley, K. C.; Marko, D. M.; Hamstra, S. I.; Braun, J. L.; Roy, B. D.; MacPherson, R. E.; Fajardo, V.
10.1101/2021.10.25.465805 — pathology — Posted on 2021-10-26
720 Genomic analysis of a parasite invasion: colonization of the Americas by the blood fluke, Schistosoma mansoni
Platt, R. N.; Le Clec'h, W.; Chevalier, F. D.; McDew-White, M.; LoVerde, P.; Ramiro de Assis, R.; Oliveira, G.; Kinung'hi, S.; Djirmay, A. G.; Steinauer, M. L.; Gouvras, A.; Rabone, M.; Webster, B. L.; Webster, J. P.; Emery, A. M.; Rollinson, D.; Anderson, T. J.
10.1101/2021.10.25.465783 — evolutionary biology — Posted on 2021-10-26
722 P300 Parameters Over the Lifespan: Validating Target Ranges from an In-Clinic Platform
Oakley, D. S.; Fosse, K.; Gerwick, E.; Joffe, D.; Oakley, D. A.; Prather, A.; Arese Lucini, F.; Palermo, F.
10.1101/2021.10.25.465715 — neuroscience — Posted on 2021-10-26
723 Natural age-related sleep-wake alterations onset prematurely in the Tg2576 mouse model of Alzheimer disease
Kollarik, S.; Moreira, C. G.; Dias, I.; Bimbiryte, D.; Miladinovic, D.; Buhmann, J. M.; Baumann, C. R.; Noain, D.
10.1101/2021.10.25.465747 — neuroscience — Posted on 2021-10-26
726 The toll-like receptor 7 agonist imiquimod increases ethanol self-administration and induces expression of toll-like receptor related genes
Lovelock, D. F.; Liu, W.; Langston, S. E.; Liu, J.; Van Voorhies, K.; Giffin, K. A.; Vetreno, R. P.; Crews, F. T.; Besheer, J.
10.1101/2021.10.25.465772 — neuroscience — Posted on 2021-10-26
727 Involvement of mechanical cues in the migration of Cajal-Retzius cells in the marginal zone during neocortical development
Lopez-Mengual, A.; Segura-Feliu, M.; Sunyer, R.; Sanz-Fraile, H.; Otero, J.; Mesquida-Veny, F.; Gil, V.; Hervera, A.; Ferrer, I.; Otin, J.; Soriano, J.; Trepat, X.; Farre, R.; Navajas, D.; del Rio, J. A.
10.1101/2021.10.25.465770 — neuroscience — Posted on 2021-10-26
728 Investigating the genetic and environmental basis of head micromovements during MRI
Beyer, F.; Horn, K.; Frenzel, S.; Hofer, E.; Knol, M. J.; Morys, F.; Vainik, U.; van der Auwera, S.; Wittfeld, K.; Saba, Y.; Adams, H.; Buelow, R.; Grabe, H.; Homuth, G.; Koini, M.; Loeffler, M.; Schmidt, H.; Schmidt, R.; Teumer, A.; Vernooij, M. W.; Villringer, A.; Voelzke, H.; Zonneveld, H.; Dagher, A.; Scholz, M.; Witte, A. V.; NeuroCHARGE consortium,
10.1101/2021.10.25.465703 — neuroscience — Posted on 2021-10-26
729 Zn2+ triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels
Varela, L.; Hendry, A. C.; Cassar, J.; Martin-Escolano, R.; Cantoni, D.; Edwards, J. C.; Abdul-Salam, V. B.; Ortega-Roldan, J. L.
10.1101/2021.10.25.465729 — biochemistry — Posted on 2021-10-26
730 Population structure in the MHC region
Marostica, A. S.; Nunes, K.; Castelli, E. C.; Silva, N. S.; Weir, B.; Goudet, J.; Meyer, D.
10.1101/2021.10.25.465726 — genetics — Posted on 2021-10-26
739 The pre-existing human antibody repertoire to computationally optimized influenza H1 hemagglutinin vaccines
Nagashima, K.; Dzimianski, J. V.; Han, J.; Abbadi, N.; Gingerich, A. D.; Royer, F.; O'Rourke, S.; Sautto, G. A.; Ross, T. M.; Ward, A. B.; DuBois, R. M.; Mousa, J.
10.1101/2021.10.25.465669 — immunology — Posted on 2021-10-26
740 Constructing the hierarchy of predictive auditory sequences in the marmoset brain
Jiang, Y.; Komatsu, M.; Chen, Y.; Xie, R.; Zhang, K.; Xia, Y.; Gui, P.; Liang, Z.; Wang, L.
10.1101/2021.10.25.465732 — neuroscience — Posted on 2021-10-26
741 Predictive coding across the left fronto-temporal hierarchy during language comprehension
Wang, L.; Schoot, L.; Brothers, T.; Alexander, E.; Warnke, L.; Kim, M.; Khan, S.; Hamalainen, M.; Kuperberg, G.
10.1101/2021.02.17.431452 — neuroscience — Posted on 2021-10-26
742 Hi-C Resolution Enhancement with Genome Sequence Data
Kriukov, D.; Koritskiy, N.; Kozlovskii, I.; Zaretckii, M.; Bazarevich, M.; Zybin, M.; Khrameeva, E.
10.1101/2021.10.25.465745 — systems biology — Posted on 2021-10-26
744 Identification of new leaf intrinsic yield genes using cross-species network analysis in plants
Curci, P. L.; Zhang, J.; Mähler, N.; Seyfferth, C.; Mannapperuma, C.; Diels, T.; Van Hautegem, T.; Jonsen, D.; Street, N. R.; Hvidsten, T. R.; Hertzberg, M.; Nilsson, O.; Inze, D.; Nelissen, H.; Vandepoele, K.
10.1101/2021.10.25.465753 — plant biology — Posted on 2021-10-26
747 Effect of OTR4120 on pulmonary fibrosis in mice
Charef, S.; Mejdoubi--Charef, N.; Chappini, F.; Papy Garcia, D.; Barritault, D.
10.1101/2021.10.24.465650 — physiology — Posted on 2021-10-26
750 Data-driven discovery of targets for bipotent anticancer drugs identifies Estrogen Related Receptor Alpha
Sahu, A.; Wang, X.; Munson, P.; Klomp, J.; Wang, X.; Gu, S.; Qian, G.; Nicol, P.; Zeng, Z.; Wang, C.; Tokheim, C.; Zhang, W.; Fu, J.; Wang, J.; Nair, N.; Rens, J.; Bourajjaj, M.; Jansen, B.; Leenders, I.; Lemmers, J.; Musters, M.; Zanten, S.; Zelst, L.; Worthington, J.; Brown, M.; Liu, J.; Juric, D.; Meyer, C.; Oubrie, A.; Liu, X. S.; Fisher, D.; Flaherty, K.
10.1101/2021.10.25.465724 — cancer biology — Posted on 2021-10-26
754 Genomic adaptation of the picoeukaryote Pelagomonas calceolata to temperate iron-poor oceans revealed by a chromosome-scale genome sequence.
Guerin, N.; Ciccarella, M.; Flamant, E.; Mangenot, S.; Istace, B.; Noel, B.; Romac, S.; Bachy, C.; Gachenot, M.; Pelletier, E.; Alberti, A.; Cruaux, C.; Wincker, P.; Aury, J.-M.; Carradec, Q.
10.1101/2021.10.25.465678 — genomics — Posted on 2021-10-26
755 sumSTAAR: a flexible framework for gene-based association studies using GWAS summary statistics
Belonogova, N. M.; Svishcheva, G. R.; Kirichenko, A. V.; Tsepilov, Y. A.; Axenovich, T. I.
10.1101/2021.10.25.465680 — genetics — Posted on 2021-10-26
758 Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4.
D'Amato, G.; Phansalkar, R.; Naftaly, J. A.; Coronado Rios, P. E.; Cowley, D. O.; Quinn, K. E.; Sharma, B.; Caron, K. M.; Vigilante, A.; Red-horse, K.
10.1101/2021.10.25.465773 — developmental biology — Posted on 2021-10-26
759 CircSry regulates spermatogenesis by enhancing γH2AX expression via sponging miR-138-5p
Song, Y.; Chen, M.; Chen, M.; Wang, H.; Gao, F.; Qiao, M.; Cao, Y.; Chen, J.; Zhang, Y.; Li, N.
10.1101/2021.10.25.465684 — developmental biology — Posted on 2021-10-26
762 Limited adaptive evolution of Staphylococcus aureus during transition from colonization to invasive infection
Räz, A. K.; Andreoni, F.; Boumasmoud, M.; Bergada Pijuan, J.; Schweizer, T. A.; Mairpady Shambat, S.; Hasse, B. K.; Zinkernagel, A. S.; Brugger, S. D.
10.1101/2021.10.25.465068 — microbiology — Posted on 2021-10-26
763 Antigen experience relaxes the organisational structure of the T cell receptor repertoire
Mark, M.; Reich-Zeliger, S.; Greenstein, E.; Reshef, D.; Madi, A.; Chain, B.; Friedman, N.
10.1101/2021.10.26.465870 — immunology — Posted on 2021-10-26
764 MDA-LDL vaccination induces athero-protective germinal center-derived antibody responses
Martos-Folgado, I.; Lorenzo, C.; Busse, C. E.; Mur, S. M.; Cobos, L.; Martin-Ventura, J. L.; Escola-Gil, J. C.; Wardemann, H.; Ramiro, A. R.
10.1101/2021.10.25.465690 — immunology — Posted on 2021-10-26
772 In silico analyses of maleidride biosynthetic gene clusters
Williams, K.; de Mattos-Shipley, K. M. J.; Willis, C. L.; Bailey, A. M.
10.1101/2021.10.26.465875 — bioinformatics — Posted on 2021-10-26
774 Pan-cancer in silico analysis of somatic mutations in G-protein coupled receptors: The effect of evolutionary conservation and natural variance
Bongers, B. J.; Gorostiola Gonzalez, M.; Wang, X.; van Vlijmen, H. W.; Jespers, W.; Gutierrez de Teran, H.; Ye, K.; IJzerman, A. P.; Heitman, L. H.; van Westen, G. J.
10.1101/2021.10.25.465693 — bioinformatics — Posted on 2021-10-26
775 Comparison of brain activity while tasting of passion fruit juice sweetened with caloric and non-caloric sweeteners
Atzingen, G. V. v.; Minano, H. L. A.; Silva, A. R.; Ortega, N. F.; Costa, E. J. X.; Silva, A. C. d. S.
10.1101/2021.10.25.465723 — bioengineering — Posted on 2021-10-26
776 Designing Biological Micro-Sensors with Chiral Nematic Liquid Crystal Droplets
Honaker, L. W.; Chen, C.; Dautzenberg, F. M. H.; Brugman, S.; Deshpande, S.
10.1101/2021.10.25.465736 — bioengineering — Posted on 2021-10-26
777 A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease
Shomroni, O.; Sitte, M.; Schmidt, J.; Parbin, S.; Ludewig, F.; Yigit, G.; Zelarayan, L. C.; Streckfuss-Bömeke, K.; Wollnik, B.; Salinas, G.
10.1101/2021.10.25.465702 — genomics — Posted on 2021-10-26
780 Prevalent sex ratio bias in Caenorhabditis nematodes
Lo, Y.-H.; Huang, Y.; Le, T. S.; Hsu, J.-C.; Yang, F.-J.; Chang, T.; Braendle, C.; Wang, J.
10.1101/2021.10.26.465869 — evolutionary biology — Posted on 2021-10-26
781 Identifying barriers to gene flow and hierarchical conservation units from seascape genomics: a modelling framework applied to a marine predator
Boussarie, G.; Momigliano, P.; Robbins, W. D.; Bonnin, L.; Cornu, J.-F.; Fauvelot, C.; Kiszka, J. J.; Manel, S.; Mouillot, D.; Vigliola, L.
10.1101/2021.10.25.465682 — ecology — Posted on 2021-10-26
783 The Isl1/Shh/Wnt5a cascade controls the invasion of myoblasts by tuning the CXCL12/CXCR4 axis during tongue morphogenesis
Zhang, W.; Yu, J.; Fu, G.; Huang, R.; Li, J.; Huang, H.; Liu, J.; Yu, D.; Gan, L.; Qiu, M.; Zhang, Z.; Li, F.
10.1101/2021.10.25.465629 — developmental biology — Posted on 2021-10-26
784 Hoxb5 reprograms murine multipotent blood progenitors into hematopoietic stem cell-like cells
Hu, F.; Huang, D.; Zhao, Q.; Weng, Q.; Zhang, Q.; Wang, K.; Liu, L.; Xia, C.; Wang, T.; Xiong, J.; Liu, X.; Guan, Y.; Geng, Y.; Dong, F.; Cheng, H.; Zhang, M.; Wang, J.
10.1101/2021.10.25.465815 — cell biology — Posted on 2021-10-26
785 The route of vaccine administration determines whether blood neutrophils undergo long-term phenotypic modifications
Feraoun, Y.; Joly, C.; Palgen, J.-L.; Tchitchek, N.; Marcos-Lopez, E.; Dereuddre-Bosquet, N.; Gallouet, A.-S.; Contreras, V.; Levy, Y.; Martinon, F.; Le Grand, R.; Beignon, A.-S.
10.1101/2021.10.26.465872 — immunology — Posted on 2021-10-26
788 Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes
Allen, J. M.; Mackos, A.; Jaggers, R. M.; Brewster, P. C.; Webb, M.; Lin, C.-H.; Ladaika, C.; White, P.; Loman, B. R.; Bailey, M. T.
10.1101/2021.10.25.465765 — immunology — Posted on 2021-10-26
789 Nuclear Export of Drosophila PERIOD contributes to temperature compensation of the circadian clock
Giesecke, A.; Johnstone, P. S.; Lamaze, A.; Landskron, J.; Atay, E.; Chen, K.-F.; Top, D.; Stanewsky, R.
10.1101/2021.10.25.465663 — neuroscience — Posted on 2021-10-26
790 Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3
Rhodes, J.; Roman, A.-O.; Bjornson, M.; Brandt, B.; Derbyshire, P.; Wyler, M.; Schmid, M.; Menke, F. L.; Santiago, J.; Zipfel, C.
10.1101/2021.10.25.465685 — plant biology — Posted on 2021-10-26
791 Intestinal Gluconeogenesis Regulates Brown and White Adipose Tissues Functions in mice
Vily-Petit, J.; Soty-Roca, M.; Silva, M.; Micoud, M.; Bron, C.; Raffin, M.; beiroa, D.; Nogueiras, R.; Roussel, D.; Gautier-stein, A.; Rajas, F.; Cota, D.; Mithieux, G.
10.1101/2021.10.25.465675 — physiology — Posted on 2021-10-26
792 Urinary bladder enlargement across nine rodent models of diabetes: correlations with glucose and insulin levels
Yesilyurt, Z. E.; Matthes, J.; Hintermann, E.; Castaneda, T. R.; Elvert, R.; Beltran-Ornelas, J. H.; Silva-Velasco, D. L.; Xia, N.; Kannt, A.; Christen, U.; Centurion, D.; Li, H.; Pautz, A.; Arioglu-Inan, E.; Michel, M. C.
10.1101/2021.10.25.465601 — pharmacology and toxicology — Posted on 2021-10-26
793 MeDUsA: A novel system for automated axon quantification to evaluate neuroaxonal degeneration
Nitta, Y.; Kawai, H.; Osaka, J.; Hakeda-Suzuki, S.; Nagai, Y.; Doubkova, K.; Suzuki, T.; Tavosanis, G.; Sugie, A.
10.1101/2021.10.25.465674 — pathology — Posted on 2021-10-26
794 Behavioral deficits, learning impairment, and enhanced hippocampal excitability in co-isogenic PrnpZH3/ZH3 mice
Matamoros-Angles, A.; Hervera, A.; Soriano, J.; Marti, E.; Carulla, P.; LLorens, F.; Nuvolone, M.; Aguzzi, A.; Ferrer, I.; Gruart, A.; Delgado-Garcia, J. M.; del Rio, J. A.
10.1101/2021.02.20.432083 — neuroscience — Posted on 2021-10-26
795 The long non-coding RNA MaTAR20 promotes mammary tumor growth by regulating angiogenesis pathways
Diermeier, S. D.; Chang, K.-C.; Frewen, A.; Taaffe, P.; Grans, J. C.; Xiong, H.; Benz, B. A.; Russo, S.; Nowak, D.; Hearn, S.; Yu, A.; Wilkinson, J. E.; Rigo, F.; Spector, D.
10.1101/2021.03.30.437774 — cancer biology — Posted on 2021-10-26
797 DROL1 subunit of U5 snRNP in the spliceosome is specifically required to splice AT--AC-type introns in Arabidopsis
Suzuki, T.; Shinagawa, T.; Niwa, T.; Akeda, H.; Hashimoto, S.; Tanaka, H.; Yamasaki, F.; Mishima, H.; Kawai, T.; Higashiyama, T.; Nakamura, K.
10.1101/2020.10.19.345900 — molecular biology — Posted on 2021-10-26
799 Geometric effects of volume to surface mapping of fMRI data
Ciantar, K. G.; Farrugia, C.; Scerri, K.; Xu, T.; Bajada, C. J.
10.1101/2020.11.09.373860 — neuroscience — Posted on 2021-10-26
800 Multi-omics analysis reveals cross-organism interactions in coral holobiont
Maruyama, T.; Ito, M.; Wakaoji, S.; Okubo, Y.; Ide, K.; Nishikawa, Y.; Fujimura, H.; Suda, S.; Nakano, Y.; Satoh, N.; Shinzato, C.; Yura, K.; Takeyama, H.
10.1101/2021.10.25.465660 — systems biology — Posted on 2021-10-26
803 Disentangling single-cell omics representation with a power spectral density-based feature extraction
Zandavi, S. M.; Koch, F.; Vijayan, A.; Zanini, F.; Mora, F. V.; Ortega, D. G.; Vafaee, F.
10.1101/2021.10.25.465657 — bioinformatics — Posted on 2021-10-26
805 Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell self-renewal, differentiation and survival
Viswanathan, V.; Cao, H.; Saiki, J.; Jiang, D.; Mattingly, A.; Nambiar, D. K.; Bloomstein, J.; Li, Y.; Jiang, S.; Chamoli, M.; Sirjani, D.; Kaplan, M.; Holsinger, F. C.; Liang, R.; Feng, Z.; Eyben, R. V.; Lagory, E.; Guan, L.; Jiang, H.; Ye, J.; Nolan, G. P.; Denko, N.; Knox, S.; Rosen, D. M.; Le, Q. T.
10.1101/2021.10.25.461994 — cell biology — Posted on 2021-10-26
806 The novel conserved NAD+ binding micropeptide SGHRT regulates mitochondrial function and metabolism in human cardiomyocytes
Foo, R.; Do, V.; Tulsian, N.; Tan, W.; Li, Z.; Cheng, L.; Autio, M. I.; Tan, W.; Tiang, Z.; Perrin, A.; Ching, J.; Ramachandra, C.; Lim, C. K.; Hausenloy, D.; Drum, C.; Richards, M.; Anand, G. S.; Bonne, I.; Lee, M.
10.1101/2021.10.24.465637 — cell biology — Posted on 2021-10-26
807 A basement membrane discovery pipeline uncovers network complexity, new regulators, and human disease associations
Jayadev, R.; Morais, M. R.; Ellingford, J. M.; Srinivasan, S.; Naylor, R. W.; Lawless, C.; Li, A. S.; Ingham, J. F.; Hastie, E.; Chi, Q.; Fresquet, M.; Koudis, N.-M.; Thomas, H. B.; O'Keefe, R. T.; Williams, E.; Adamson, A.; Stuart, H. M.; Banka, S.; Smedley, D.; Genomics England Research Consortium, ; Sherwood, D. R.; Lennon, R.
10.1101/2021.10.25.465762 — cell biology — Posted on 2021-10-26
809 Epidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling
Hegazy, M.; Koetsier, J. L.; Huffine, A. L.; Broussard, J. A.; Godsel, B. M.; Godsel, L. M.; Green, K. J.
10.1101/2021.10.25.464989 — cell biology — Posted on 2021-10-26
810 The regenerative response of cardiac interstitial cells
Rolland, L.; Harrington, A.; Faucherre, A.; Gangatharan, G.; Gamba, L.; Severac, D.; Pratlong, M.; Moore-Morris, T.; Jopling, C.
10.1101/2021.10.25.465720 — cell biology — Posted on 2021-10-26
811 Trisomy 21 increases microtubules and disrupts centriolar satellite localization
McCurdy, B. L.; Jewett, C. E.; StemmWolf, A. J.; Duc, H. N.; Joshi, M.; Espinosa, J. M.; Prekeris, R.; Pearson, C. G.
10.1101/2021.10.25.465808 — cell biology — Posted on 2021-10-26
813 Treatment of waste stabilization pond effluent using natural zeolite for irrigation potential
Meiramkulova, K.; Mkilima, T.; Temirbekova, A.; Bukenova, E.; Meirbekov, A.; Saspugayeva, G.; Adilbektegi, G.; Beisembayeva, K.; Tazhkenova, G.
10.1101/2021.10.25.465710 — scientific communication and education — Posted on 2021-10-25
814 Regulation of skeletal muscle metabolism and contraction performance via teneurin-latrophilin action.
Reid, A.; Hogg, D.; Dodsworth, T.; Chen, Y.; Reid, R.; Xu, M.; Husic, M.; Biga, P.; Slee, A.; Buck, L.; Barsyte-Lovejoy, D.; Locke, M.; Lovejoy, D.
10.1101/2021.10.25.465698 — physiology — Posted on 2021-10-25
818 Alternative strategy to induce CRISPR-mediated genetic changes in hematopoietic cells
Gonzalez-Romero, E.; Rosal-Vela, A.; Liquori, A.; Martinez-Valiente, C.; Garcia-Garcia, G.; Millan, J. M.; Sanz, M. A.; Cervera, V. J.; Vazquez-Manrique, R. P.
10.1101/2021.10.25.465699 — molecular biology — Posted on 2021-10-25
822 Multi-trait and multi-environment Bayesian analysis to predict the G x E interaction in flood-irrigated rice
da Silva Junior, A. C.; SantAnna, I. d. C.; Silva, M. J.; Cruz, C. D.; Azevedo, C. F.; Nascimento, M.; Soares, P. C.
10.1101/2021.10.25.465700 — plant biology — Posted on 2021-10-25
824 Spatially Patterned Bi-electrode Epiretinal Stimulation for Axon Avoidance at Cellular Resolution
Vilkhu, R. S.; Madugula, S. S.; Grosberg, L. E.; Gogliettino, A. R.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Mitra, S.; Chichilnisky, E. J.
10.1101/2021.08.17.454395 — bioengineering — Posted on 2021-10-25
826 Genomic adaptation in the CAZyome and specialised metabolism of the plant-associated Streptomyces violaceusniger clade
Gayrard, D.; Veyssiere, M.; Adam, K.; Martinez, Y.; Vandecasteele, C.; Vidal, M.; Dumas, B.; Rey, T.
10.1101/2021.10.25.465742 — genomics — Posted on 2021-10-25
827 Evolution of diapause in the African turquoise killifish by remodeling ancient gene regulatory landscape
Singh, P. P.; Reeves, G. A.; Contrepois, K.; Ellenberger, M.; Hu, C.-K.; Snyder, M. P.; Brunet, A.
10.1101/2021.10.25.465616 — genomics — Posted on 2021-10-25
828 KTD1 is a yeast defense factor against K28 killer toxin
Andreev, I.; Giovanetti, S. M.; Urtecho, G.; Shriner, D.; Bloom, J. S.; Sadhu, M. J.
10.1101/2021.10.25.465803 — genetics — Posted on 2021-10-25
830 MiR-30a-5p alters epidermal terminal differentiation during aging by regulating BNIP3L/NIX-dependent mitophagy
CHEVALIER, F. P.; RORTEAU, J.; FERRARO, S.; MARTIN, L. S.; GONZALEZ-TORRES, A.; BERTHIER, A.; El-Kholti, N.; LAMARTINE, J.
10.1101/2021.10.25.465713 — cell biology — Posted on 2021-10-25
831 Biochemical propensity mapping for structural and functional anatomy of importin α IBB domain
Jibiki, K.; Liu, M.; Chaosen, L.; Kodama, T. S.; Kojima, C.; Fujiwara, T.; Yasuhara, N.
10.1101/2021.10.25.465662 — cell biology — Posted on 2021-10-25
832 Homosalate boosts the release of tumor-derived Extracellular Vesicles with anti-anoikis properties
Grisard, E.; Lescure, A.; Nevo, N.; Corbe, M.; Jouve, M.; Lavieu, G.; Joliot, A.; Del Nery, E.; martin jaular, l.; Thery, C.
10.1101/2021.10.25.465564 — cell biology — Posted on 2021-10-25
834 Molecular identification of rhizobacterial isolates from Prosopis limensis and their effect on the growth of Raphanus sativus under salt stress
Clavo, R. F.; Valladolid-Suyon, E.; Reynosa-Farronan, K.; Ortega, C. D. A.; Valdera, G. Z.; Garboggini, F. F.; Iglesias-Osore, S.; Farfan, C. R. C.
10.1101/2021.10.25.464584 — molecular biology — Posted on 2021-10-25
840 A MademoiseLLE domain binding platform links the key RNA transporter to endosomes
Devan, S.-K.; Schott-Verdugo, S.; Muentjes, K.; Bismar, L.; Reiners, J.; Hachani, E.; Schmitt, L.; Hoeppner, A.; Smits, S. H.; Gohlke, H.; Feldbruegge, M.
10.1101/2021.10.25.465676 — microbiology — Posted on 2021-10-25
841 Gut microbiota analyses of Saudi populations for type 2 diabetes-related phenotypes reveals significant association
AlAli, A.; Al-Muhanna, F. A.; Dodwell, A. k.; Al Eleq, A. H.; Al-Rubaish, A. M.; Albaker, W. I.; Al-Sultan, A. I.; Alkharsah, K. R.; Sulaiman, R. M.; Al-Qurain, A. A.; Cyrus, C. K.; AlAli, R. A.; Vatte, C.; Robinson, F. L.; Nguyen, C.; Brooks, A. W.; Zhou, X.; Snyder, M. P.; Almuhanna, A. F.; Keating, B. J.; Piening, B. D.
10.1101/2021.10.25.465666 — microbiology — Posted on 2021-10-25
842 Autotaxin may play a Critical Role between the Genetic Risk Factors and Pathogenesis of SLE in Plasmacytoid Dendritic Cells
Tsuchida, Y.; Shoda, H.; Nakano, M.; Ota, M.; Okamura, T.; Yamamoto, K.; Kurano, M.; Yatomi, Y.; Fujio, K.; Sawada, T.
10.1101/2021.10.25.465592 — immunology — Posted on 2021-10-25
846 BET Bromodomain Inhibitors Target the NEUROD1-subtype SCLC by Blocking NEUROD1 Transactivation
Chen, H.; Gesumaria, L.; Park, Y.-K.; Oliver, T. G.; Singer, D. S.; Ge, K.; Schrump, D. S.
10.1101/2021.10.25.465771 — cancer biology — Posted on 2021-10-25
848 Spinning sugars in antigen biosynthesis: a direct study of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
Cross, A. R.; Roy, S.; Vivoli Vega, M.; Rejzek, M.; Nepogodiev, S. A.; Cliff, M.; Salmon, D.; Isupov, M. N.; Field, R. A.; Prior, J. L.; Harmer, N. J.; Glycoengineering of Veterinary Vaccines (GoVV),
10.1101/2021.10.25.465559 — biochemistry — Posted on 2021-10-25
849 Identification of the Park Grass Experiment soil metaproteome
Quinnn, G. A.; Abdelhameed, A. M.; Banat, I. M.; Berrar, D.; Doerr, S.; Dudley, E.; Francis, L. W.; Gazze, S. A.; Hallin, I. V.; Matthews, G. P.; Swain, M. T.; Whalley, W. R.; van Keulen, G.
10.1101/2021.10.25.465615 — biochemistry — Posted on 2021-10-25
851 Cancer malignancy is correlated with up-regulation of PCYT2-mediated glycerol phosphate modification of α-dystroglycan
Umezawa, F.; Natsume, M.; Fukusada, S.; Nakajima, K.; Yamasaki, F.; Kawashima, H.; Kuo, C.-W.; Khoo, K.-H.; Shimura, T.; Yagi, H.; Kato, K.
10.1101/2021.10.25.465649 — biochemistry — Posted on 2021-10-25
854 SSAM-lite: a light-weight web app for rapid analysis of spatially resolved transcriptomics data
Tiesmeyer, S.; Sahay, S.; Müller-Bötticher, N.; Eils, R.; Mackowiak, S. D.; Ishaque, N.
10.1101/2021.09.29.462194 — bioinformatics — Posted on 2021-10-25
857 Zika virus infection drives epigenetic modulation of immunity by the histone acetyltransferase CBP of Aedes aegypti
Amarante, A. d. M.; da Silva, I. C. d. A.; Vicentino, A. R. R.; Carneiro, V. C.; Pinto, M. d. A.; Higa, L. M.; Moharana, K. C.; da Cunha, O. A. T.; Venancio, T. M.; de Oliveira, P. L.; Fantappie, M. R.
10.1101/2021.10.22.463187 — molecular biology — Posted on 2021-10-25
858 An ancestral interaction module promotes oligomerisation in divergent mitochondrial ATP synthases
Gahura, O.; Muhleip, A.; Hierro-Yap, C.; Panicucci, B.; Jain, M.; Slapnickova, M.; Amunts, A.; Zikova, A.
10.1101/2021.10.10.463820 — molecular biology — Posted on 2021-10-25
862 Membrane-Tethered Mucin 1 is Stimulated by Interferon in Multiple Cell Types and Antagonizes Influenza A Virus Infection in Human Airway Epithelium
Iverson, E.; Griswold, K.; Song, D.; Gagliardi, T. B.; Hamidzadeh, K.; Kesimer, M.; Sinha, S.; Perry, M.; Duncan, G. A.; Scull, M. A.
10.1101/2021.03.11.434997 — microbiology — Posted on 2021-10-25
863 A Histoplasma capsulatum lipid metabolic map identifies antifungal targets
Zamith-Miranda, D.; Heyman, H. M.; Burnet, M. C.; Couvillion, S. P.; Zheng, X.; Munoz, N.; Nelson, W. C.; Kyle, J. E.; Zink, E. M.; Weitz, K. K.; Bloodsworth, K. J.; Clair, G. C.; Zucker, J. D.; Teuton, J. R.; Payne, S. H.; Kim, Y.-M.; Reyes Gil, M.; Baker, E. S.; Bredeweg, E. L.; Nosanchuk, J. D.; Nakayasu, E. S.
10.1101/2020.03.02.973412 — microbiology — Posted on 2021-10-25
864 Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury
Cross, A. R.; de Andrea, C.; Villalba-Esparza, M.; Landecho Acha, M.; Cerundolo, L.; Weeratunga, P.; Etherington, R.; Denney, L.; Ogg, G.; Ho, L.-P.; Roberts, I.; Hester, J.; Klenerman, P.; Melero, I.; Sansom, S.; Issa, F.
10.1101/2021.06.21.449178 — immunology — Posted on 2021-10-25
866 Amphetamine alters an EEG marker of reward processing in humans and mice
Cavanagh, J. F.; Olguin, S.; Talledo, J.; Kotz, J.; Roberts, B.; Nungary, J. A.; Sprock, J.; Gregg, D.; Bhakta, S. G.; Light, G. A.; Swerdlow, N. R.; Young, J. W.; Brigman, J. L.
10.1101/2021.08.25.457689 — neuroscience — Posted on 2021-10-25
867 Identifying tumor cells at the single cell level
Dohmen, J.; Baranovskii, A.; Uyar, B.; Ronen, J.; Franke, V.; Akalin, A.
10.1101/2021.10.15.463909 — cancer biology — Posted on 2021-10-25
868 Shared hotspot mutations in spontaneously arising cancers position dog as an unparalleled comparative model for precision therapeutics
Rodrigues, L.; Watson, J.; Feng, Y.; Lewis, B.; Harvey, G.; Post, G.; Megquier, K.; Lambert, L.; Miller, A.; Lopes, C.; Zhao, S.
10.1101/2021.10.22.465469 — cancer biology — Posted on 2021-10-25
869 PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery
Koc, S.; Lloyd, M. W.; Grover, J.; Seepo, S.; Lakshmi Subramanian, S.; Ray, M.; Frech, C.; DiGiovanna, J.; Webster, P.; Neuhauser, S.; Srivastava, A.; Yi Woo, X.; Sanderson, B. J.; White, B.; Lott, P.; PDXNet Consortium, ; Evrard, Y. A.; Wallace, T. A.; Moscow, J. A.; Doroshow, J. H.; Mitsiades, N.; Kaochar, S.; Pan, C.-x.; Chen, M. S.; Carvajal-Carmona, L.; Welm, A. L.; Welm, B. E.; Lewis, M. T.; Ramaswarmy, G.; Ding, L.; Li, S.; Herlyn, M.; Davies, M.; Roth, J.; Meric-Bernstam, F.; Robinson, P. N.; Bult, C. J.; Davis-Dusenbery, B.; Dean, D. A.; Chuang, J. H.
10.1101/2021.10.15.464537 — cancer biology — Posted on 2021-10-25
870 Connecting conformational stiffness of the protein with energy landscape by a single experiment
chakraborty, S.; Chaudhuri, D.; Chaudhuri, D.; Singh, V.; Banerjee, S.; Haldar, S.
10.1101/2020.06.09.142257 — biophysics — Posted on 2021-10-25
874 RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine
Wood, E. C.; Glen, A. K.; Kvarfordt, L. G.; Womack, F.; Acevedo, L.; Yoon, T. S.; Ma, C.; Flores, V.; Sinha, M.; Roach, J. C.; Mendoza, L.; Hoffman, A. S.; Deutsch, E. W.; Koslicki, D.; Ramsey, S. A.
10.1101/2021.10.17.464747 — bioinformatics — Posted on 2021-10-25
875 Optimal balancing of clinical factors in large scale clinical RNA-Seq studies
CHIANG, A. W. T.; Gazestani, V. H.; Altieri, M. G.; Kellman, B. P.; Nalabolu, S. P.; Pramparo, T.; Pierce, K.; Courchesne, E.; Lewis, N. E.
10.1101/2021.06.30.450639 — bioinformatics — Posted on 2021-10-25
877 A 6-CpG Validated Methylation Risk Score Model for Metabolic Syndrome: The HyperGEN and GOLDN Studies
Hidalgo, B. A.; Minniefield, B. A.; Patki, A.; Tanner, R.; Bagheri, M.; Tiwari, H. A.; Arnett, D.; Irvin, M. R.
10.1101/2021.10.22.465467 — genetics — Posted on 2021-10-25
880 A novel, ataxic mouse model of Ataxia Telangiectasia caused by a clinically relevant nonsense mutation
Perez, H.; Abdallah, M. F.; Chavira, J. I.; Norris, A. S.; Egeland, M. T.; Vo, K. L.; Sanghez, V.; Buechsenschuetz, C. L.; Kim, J. L.; Pind, M.; Nakamura, K.; Hicks, G. G.; Gatti, R. A.; Madrenas, J.; Iacovino, M.; McKinnon, P.; Mathews, P. J.
10.1101/2020.11.23.394098 — neuroscience — Posted on 2021-10-25
881 Differential impact of Kv8.2 loss on rod and cone signaling and degeneration.
Inamdar, S. M.; Lankford, C. K.; Poria, D.; Laird, J. G.; Solessio, E.; Kefalov, V. J.; Baker, S. A.
10.1101/2021.07.05.451197 — neuroscience — Posted on 2021-10-25
883 Plant structural and nutritional responses to drought differ among common pasture species
Catunda, K. L. M.; Churchill, A. C.; Power, S. A.; Zhang, H.; Fuller, K. J.; Moore, B. D.
10.1101/2021.10.24.465597 — plant biology — Posted on 2021-10-25
885 The geometry of decision-making
Sridhar, V. H.; Li, L.; Gorbonos, D.; Nagy, M.; Schell, B. R.; Sorochkin, T.; Gov, N. S.; Couzin, I. D.
10.1101/2021.05.26.445795 — animal behavior and cognition — Posted on 2021-10-25
886 Integrating melt-electrowriting and inkjet bioprinting for engineering structurally organized articular cartilage
DUFOUR, A.; Barcelo Gallostra, X.; OKeeffe, C.; Eichholz, K. F.; Von Euw, S.; Garcia, O.; Kelly, D. J.
10.1101/2021.10.24.465623 — bioengineering — Posted on 2021-10-25
890 Hyaluronan and Elastin-Like Protein (HELP) Gels Significantly Improve Cargo Retention in the Myocardium
Suhar, R. A.; Doulames, V. M.; Liu, Y.; Hefferon, M. E.; Figueroa, O.; Buabbas, H.; Heilshorn, S. C.
10.1101/2021.10.24.465557 — bioengineering — Posted on 2021-10-25
895 Infants' attention to eyes is an independent, heritable trait predicting later verbal competence
Viktorsson, C.; Portugal, A. M.; Li, D.; Rudling, M.; Siqueiros Sanchez, M.; Tammimies, K.; Taylor, M. J.; Ronald, A.; Falck-Ytter, T.
10.1101/2021.10.23.465424 — developmental biology — Posted on 2021-10-25
896 Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers
Mao, Q.; Acharya, A.; Rodriguez-delaRosa, A.; Marchiano, F.; Dehapiot, B.; Al Tanoury, Z.; Rao, J.; Diaz-Cuadros, M.; Mansur, A.; Wagner, E.; Chardes, C.; Gupta, V. A.; Lenne, P.-F.; Habermann, B. H.; Pourquie, O.; Schnorrer, F.
10.1101/2021.10.24.465614 — developmental biology — Posted on 2021-10-25
898 A Biodegradable, Tacrolimus-releasing Nerve Wrap Promotes Peripheral Nerve Regeneration
Daeschler, S. C.; Chan, K.; Feinberg, K.; Manoraj, M.; Cheung, J.; Zhang, J.; Santerre, J. P.; Gordon, T.; Borschel, G. H.
10.1101/2021.10.23.465561 — neuroscience — Posted on 2021-10-25
901 General dimensions of human brain morphometry inferred from genome-wide association data
Fürtjes, A. E.; Arathimos, R.; Coleman, J. R.; Cole, J. H.; Cox, S. R.; Deary, I. J.; de la Fuente, J.; Madole, J. W.; Tucker-Drob, E. M.; Ritchie, S. J.
10.1101/2021.10.22.465437 — genetics — Posted on 2021-10-25
904 Diverse northern Asian and Jomon-related genetic structure discovered among socially complex Three Kingdoms period Gaya region Koreans
Gelabert, P.; Blazyte, A.; Chang, Y.; Fernandes, D.; Jeon, S.; Hong, J. G.; Yoon, J.; Ko, Y.; Oberreiter, V.; Cheronet, O.; Ozdogan, K. T.; Sawyer, S.; Yang, S.; Greytak, E. M.; Kim, J.; Choi, H.; Kim, J.-I.; Bae, K.; Bhak, J.; Pinhasi, R.
10.1101/2021.10.23.465563 — evolutionary biology — Posted on 2021-10-25
905 The gut microbiome is associated with cocaine behavior and predicts addiction vulnerability in adult male rats
Suess, G. J.; Kasiah, J.; Simpson, S.; Brennan, M.; Conlisk, D.; Maturin, L.; George, O.; Chassaing, B.; Frantz, K. J.
10.1101/2021.07.20.453110 — neuroscience — Posted on 2021-10-25
906 Real-Time Structure Search and Structure Classification for AlphaFold Protein Models
Aderinwale, T.; Bharadwaj, V.; Christoffer, C.; Terashi, G.; Zhang, Z.; Jahandideh, R.; Kagaya, Y.; Kihara, D.
10.1101/2021.10.21.465371 — bioinformatics — Posted on 2021-10-25
907 Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis
Dashti, Y.; Mohammadipanah, F.; Belousoff, M. J.; Vocat, A.; Zabala, D.; Fage, C. D.; Romero-Canelon, I.; Bunk, B.; Sproer, C.; Overmann, J.; Cole, S. T.; Challis, G. L.
10.1101/2021.10.24.465558 — microbiology — Posted on 2021-10-25
908 High glucose enhances antigen-independent CTL killing via TRAIL
Yang, W.; Denger, A.; Diener, C.; Kueppers, F.; Soriano-Baguet, L.; Schaefer, G.; Yanamandra, A. K.; Zhao, R.; Knoerck, A.; Schwarz, E. C.; Hart, M.; Lammert, F.; Roma, L. P.; Brenner, D.; Grigorios Christidis, G.; Helms, V.; Meese, E.; Hoth, M.; Qu, B.
10.1101/2021.08.04.455060 — immunology — Posted on 2021-10-25
909 SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19
Martinez-Colon, G. J.; Ratnasiri, K.; Chen, H.; Jiang, S.; Zanley, E.; Rustagi, A.; Verma, R.; Chen, H.; Andrews, J. R.; Mertz, K.; Tzankov, A.; Azagury, D.; Boyd, J.; Nolan, G. P.; Schürch, C. M.; Matter, M. S.; Blish, C. A.; McLaughlin, T. L.
10.1101/2021.10.24.465626 — immunology — Posted on 2021-10-25
911 Dynamic Ins2 gene activity defines β cell maturity states
Modi, H.; Chu, C. M. J.; Skovso, S.; Ellis, C.; Krentz, N. A. J.; Zhao, Y. B.; Cen, H.; Noursadeghi, N.; Panzhinskiy, E.; Hu, X.; Dionne, D. A.; Xia, Y. h.; Xuan, S.; Huising, M. O.; Kieffer, T. J.; Lynn, F. C.; Johnson, J.
10.1101/702589 — cell biology — Posted on 2021-10-25
914 Single molecule tracking the uncoupling of assembly and membrane insertion in Perfringolysin O
Senior, M. J.; Monico, C.; Weatherill, E. E.; Gilbert, R.; Heuck, A.; Wallace, M. I.
10.1101/2021.05.26.445776 — biophysics — Posted on 2021-10-25
915 Large-scale geographic survey provides insights into the colonization history of a major aphid pest on its cultivated apple host in Europe, North America and North Africa
Olvera-Vazquez, S. G.; Remoue, C.; Venon, A.; Rousselet, A.; Grandcolas, O.; Azrine, M.; Momont, L.; Galan, M.; Benoit, L.; David, G.; Alhmedi, A.; Belien, T.; Alins, G.; Franck, P.; Haddioui, A.; Jacobsen, S. K.; Andreev, R.; Simon, S.; Sigsgaard, L.; Guibert, E.; Tournant, L.; Gazel, F.; Mody, K.; Khachtib, Y.; Roman, A.; Ursu, T. M.; Zakharov, I. A.; Belcram, H.; Harry, M.; Roth, M.; Simon, J. C.; Oram, S.; Ricard, J. M.; Agnello, A.; Beers, E. H.; Engelman, J.; Balti, I.; Salhi-Hannachi, A.; Zhang, H.; Tu, H.; Mottet, C.; Barres, B.; Degrave, A.; Razmjou, J.; Giraud, T.; Falque, M.; Dapena
10.1101/2020.12.11.421644 — evolutionary biology — Posted on 2021-10-25
916 Roles of proteins containing immunoglobulin-like domains in the conjugation of bacterial plasmids.
Huttener, M.; Hergueta, J.; Bernabeu, M.; Prieto, A.; Aznar, S.; Merino, S.; Tomas, J.; Juarez, A.
10.1101/2021.07.22.453378 — microbiology — Posted on 2021-10-25
917 Effect of SSRI discontinuation on anxiety-like behaviours in mice
Collins, H. M.; Pinacho, R.; Ozdemir, D.; Bannerman, D. M.; Sharp, T.
10.1101/2021.05.29.446266 — neuroscience — Posted on 2021-10-25
918 Photoprotection is regulated by light-independent CO2 availability
Ruiz-Sola, M. A.; Flori, S.; Yuan, Y.; Villain, G.; Sanz-Luque, E.; Redekop, P.; Tokutsu, R.; Küken, A.; Tsichla, A.; Kepesidis, G.; Allorent, G.; Arend, M.; Iacono, F.; Finazzi, G.; Hippler, M.; Nikoloski, Z.; Minagawa, J.; Grossman, A. R.; Petroutsos, D.
10.1101/2021.10.23.465040 — plant biology — Posted on 2021-10-25
919 How ancient forest fragmentation and riparian connectivity generate high levels of genetic diversity in a micro-endemic Malagasy tree
Salmona, J.; Dresen, A.; Ranaivoson, A. E.; Manzi, S.; Le Pors, B.; Hong-Wa, C.; Razanatsoa, J.; Andriaholinirina, N. V.; Rasoloharijaona, S.; Vavitsara, M.-E.; Besnard, G.
10.1101/2020.11.25.394544 — genomics — Posted on 2021-10-25
921 CRISPR/Cas9 screen for functional MYC binding sites reveals MYC-dependent vulnerabilities in K562 cells
Kazimierska, M.; Podralska, M.; Zurawek, M.; Wozniak, T.; Kasprzyk, M. E.; Sura, W.; Losiewski, W.; Ziolkowska-Suchanek, I.; Kluiver, J. L.; van den Berg, A.; Rozwadowska, N.; Dzikiewicz-Krawczyk, A.
10.1101/2021.08.02.454734 — molecular biology — Posted on 2021-10-25
922 Production of Offspring from Azoospermic Mice with Meiotic Failure: Precise Biparental Meiosis within Halved Oocytes
Ogonuki, N.; Kyogoku, H.; Hino, T.; Osawa, Y.; Fujiwara, Y.; Inoue, K.; Kunieda, T.; Mizuno, S.; Tateno, H.; Sugiyama, F.; Kitajima, T.; Ogura, A.
10.1101/2021.09.03.458818 — developmental biology — Posted on 2021-10-25
923 Zika virus infection drives epigenetic modulation of immunity by the histone acetyltransferase CBP of Aedes aegypti
Amarante, A. d. M.; da Silva, I. C. d. A.; Vicentino, A. R. R.; Carneiro, V. C.; Pinto, M. d. A.; Higa, L. M.; Moharana, K. C.; da Cunha, O. A. T.; Venancio, T. M.; de Oliveira, P. L.; Fantappie, M. R.
10.1101/2021.10.22.463187 — molecular biology — Posted on 2021-10-25
925 Computational capability of ecological dynamics
Ushio, M.; Watanabe, K.; Fukuda, Y.; Tokudome, Y.; Nakajima, K.
10.1101/2021.09.15.460556 — ecology — Posted on 2021-10-24
927 CIITA induces expression of MHC-I and MHC-II in transmissible cancers
Ong, C. E. B.; Cheng, Y.; Siddle, H.; Lyons, A. B.; Woods, G. M.; Flies, A. S.
10.1101/2021.07.14.452299 — immunology — Posted on 2021-10-24
928 Opposing roles of blood-borne monocytes and tissue-resident macrophages in limbal stem cell damage after ocular injury
Zhou, C.; Lei, F.; Mittermaier, M.; Ksander, B.; Dana, R.; Dohlman, C. H.; Vavvas, D. G.; Chodosh, J.; Paschalis, E. I.
10.1101/2021.07.25.453707 — immunology — Posted on 2021-10-24
938 A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens
Price, S.; Bhosle, S. G.; Goncalves, E.; Li, X.; McClurg, D.; Barthorpe, A.; Beck, A.; Hall, C.; Lightfoot, H.; Farrow, L.; Ansari, R.; Jackson, D. A.; Allen, L.; Roberts, K.; Beaver, C.; Francies, H.; Garnett, M.
10.1101/2021.10.23.464385 — cancer biology — Posted on 2021-10-24
939 Fast and parallel nanoscale 3D tracking of heterogeneous mammalian chromatin dynamics
Gustavsson, A.-K.; Ghosh, R. P.; Petrov, P. N.; Liphardt, J. T.; Moerner, W. E.
10.1101/2021.10.24.465625 — biophysics — Posted on 2021-10-24
940 Bicolor angelfish (Centropyge bicolor) provides the first chromosome-level genome of the Pomacanthidae family
Li, C.; Yang, X.; Shao, L.; Zhang, R.; Liu, Q.; Zhang, M.; Liu, S.; Pan, S.; Xue, W.; Wang, C.; Mao, C.; Zhang, H.; Fan, G.
10.1101/2021.10.24.465606 — genomics — Posted on 2021-10-24
941 Compatibility logic of human enhancer and promoter sequences
Bergman, D. T.; Jones, T. R.; Liu, V.; Siraj, L.; Kang, H. Y.; Nasser, J.; Nguyen, T. H.; Grossman, S. R.; Fulco, C. P.; Lander, E. S.; Engreitz, J. M.
10.1101/2021.10.23.462170 — genetics — Posted on 2021-10-24
943 Stemness activity underlying whole brain regeneration in a basal chordate
Gordon, T.; Zaquin, T.; Kowarsky, M. A.; Voskoboynik, Y.; Hendin, N.; Wurtzel, O.; Caicci, F.; Manni, L.; Voskoboynik, A.; Shenkar, N.
10.1101/2021.10.24.465595 — developmental biology — Posted on 2021-10-24
944 A Prion that regulates genome diversification
Byers, J. S.; Futia, R. A.; Elgort, A. V.; Lozanoski, T. M.; Garcia, D. M.; Jarosz, D. F.
10.1101/2021.10.23.465590 — molecular biology — Posted on 2021-10-24
947 Spatial coding in the hippocampus of flying owls
Agarwal, A.; Sarel, A.; Derdikman, D.; Ulanovsky, N.; Gutfreund, Y.
10.1101/2021.10.24.465553 — neuroscience — Posted on 2021-10-24
948 Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs
Lumeau, A.; Bery, N.; Frances, A.; Gayral, M.; Ribeyre, C.; Lopez, C.; Nevot, A.; El kaoutari, A.; Labrousse, G.; Madrid-Mencia, M.; Pillaire, M.-J.; Pancaldi, V.; Bergoglio, V.; Dusetti, N. J. V.; Hoffmann, J.-S.; Buscail, L.; Lutzmann, M.; Cordelier, P.
10.1101/2021.10.23.465566 — cancer biology — Posted on 2021-10-24
950 Dynamics of lipids in the yeast lipid droplets
Fomina, M.; Mamontov, E.; O'Neill, H.; Close, D.; Borreguero, J.; Morrell-Falvey, J.
10.1101/2021.10.22.465485 — biophysics — Posted on 2021-10-24
953 Quantification of breeding sites parameters in shaping bacterial communities in Aedes aegypti (Diptera: Culicidae).
Guimond, J.; Hery, L.; Guidez, A.; Durand, A.-A.; Delannay, C.; Issaly, J.; Raffestin, S.; Nigro, J.; Vega-Rua, A.; Constant, P.; Guertin, C.; Dusfour, I.
10.1101/2021.10.24.465617 — ecology — Posted on 2021-10-24
955 ARP2/3- and resection-coupled genome reorganization facilitates translocations
Zagelbaum, J.; Schooley, A.; Zhao, J.; Schrank, B. R.; Callen, E.; Zha, S.; Gottesman, M.; Nussenzweig, A.; Rabadan, R.; Dekker, J.; Gautier, J.
10.1101/2021.10.22.465487 — molecular biology — Posted on 2021-10-24
957 Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis
Dashti, Y.; Mohammadipanah, F.; Belousoff, M. J.; Vocat, A.; Zabala, D.; Fage, C. D.; Romero-Canelon, I.; Bunk, B.; Sproer, C.; Overmann, J.; Cole, S. T.; Challis, G. L.
10.1101/2021.10.24.465558 — microbiology — Posted on 2021-10-24
958 SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes
Oliveira, L. G.; Angelo, Y. d. S.; Yamamoto, P.; Carregari, V. C.; Crunfli, F.; Reis-de-Oliveira, G.; Costa, L.; Duque, E. A.; Santos, N. B.; Almeida, G. M.; Firmino, E. M. S.; Paiva, I. M.; Polonio, C. M.; Zanluqui, N. G.; Oliveira, M. G.; Davanzo, G. G.; Ayupe, M. C.; Salgado, C. L.; Campos, A. C. A.; Goes, L. G. B.; Cunha, M. P.; Lima, M. R. D.; Fonseca, D. M.; Guimaraes, A. M. S.; Minoprio, P. M.; Munhoz, C. D.; Mori, C. M. C.; Moraes-Vieira, P. M.; Cunha, T. M.; Martins-de-Souza, D.; Peron, J. P. S.
10.1101/2021.10.23.465567 — immunology — Posted on 2021-10-24
959 Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway
Gagne, M.; Corbett, K. S.; Flynn, B. J.; Foulds, K. E.; Wagner, D. A.; Andrew, S. F.; Todd, J.-P. M.; Honeycutt, C. C.; McCormick, L.; Nurmukhambetova, S. T.; Davis-Gardner, M. E.; Pessaint, L.; Bock, K. W.; Nagata, B. M.; Minai, M.; Werner, A. P.; Moliva, J. I.; Tucker, C.; Lorang, C. G.; Zhao, B.; McCarthy, E.; Cook, A.; Dodson, A.; Mudvari, P.; Roberts-Torres, J.; Laboune, F.; Wang, L.; Goode, A.; Kar, S.; Boyoglu-Barnum, S.; Yang, E. S.; Shi, W.; Ploquin, A.; Doria-Rose, N.; Carfi, A.; Mascola, J. R.; Boritz, E. A.; Edwards, D. K.; Andersen, H.; Lewis, M. G.; Suthar, M. S.; Graham, B. S.;
10.1101/2021.10.23.465542 — immunology — Posted on 2021-10-24
960 A transcriptomic axis predicts state modulation of cortical interneurons
Bugeon, S.; Duffield, J.; Dipoppa, M.; Prankerd, I.; Ritoux, A.; Nicoloutsopoulos, D.; Orme, D.; Shinn, M.; Peng, H.; Forrest, H.; Viduolyte, A.; Bai Reddy, C.; Isogai, Y.; Carandini, M.; Harris, K. D.
10.1101/2021.10.24.465600 — neuroscience — Posted on 2021-10-24
962 The humanized nanobody RBD-1-2G tolerates the spike N501Y mutation to neutralize SARS-CoV-2
Fu, Y.; da Fonseca Rezende e Mello, J.; Fleming, B. D.; Renn, A.; Chen, C. Z.; Hu, X.; Xu, M.; Gorshkov, K.; Hanson, Q.; Zheng, W.; Lee, E. M.; Perera, L.; Petrovich, R.; Pradhan, M.; Eastman, R. T.; Itkin, Z.; Stanley, T.; Hsu, A.; Dandey, V.; Gillette, W.; Taylor, T.; Ramakrishnan, N.; Perkins, S.; Esposito, D.; Oh, E.; Susumu, K.; Wolak, M.; Ferrer, M.; Hall, M. D.; Borgnia, M. J.; Simeonov, A.
10.1101/2021.10.22.465476 — synthetic biology — Posted on 2021-10-24
964 Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants
Iaconis, D.; Talarico, C.; Manelfi, C.; Cesta, M. C.; Zippoli, M.; Caccuri, F.; Matusali, G.; Bordi, L.; Scorzolini, L.; Bucci, E. M.; Caruso, A.; Nicastri, E.; Allegretti, M.; Beccari, A. R.
10.1101/2021.10.22.465294 — pharmacology and toxicology — Posted on 2021-10-24
965 The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC
Javitt, A.; Shmueli, M. D.; Kramer, M. P.; Kolodziejczyk, A. A.; Cohen, I. J.; Kamer, I.; Litchfield, K.; Bab-Dinitz, E.; Zadok, O.; Neiens, V.; Ulman, A.; Radomir, L.; Wolf-Levy, H.; Eisenberg-Lerner, A.; Kacen, A.; Alon, M.; Toste Rego, A.; Stacher-Priehse, E.; Linder, M.; Koch, I.; Bar, J.; Swanton, C.; Samuels, Y.; Levin, Y.; C. A. da Fonseca, P.; Elinav, E.; Friedman, N.; Meiners, S.; Merbl, Y.
10.1101/2021.10.24.464690 — cancer biology — Posted on 2021-10-24
966 A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer
Haderk, F.; Fernandez-Mendez, C.; Cech, L.; Yu, J.; Meraz, I. M.; Olivas, V.; Barbosa Rabago, D.; Kerr, D. L.; Gomez, C.; Allegakoen, D. V.; Guan, J.; Shah, K. N.; Herrington, K. A.; Gbenedio, O. M.; Nanjo, S.; Majidi, M.; Tamaki, W.; Rotow, J. K.; McCoach, C. E.; Riess, J. W.; Gutkind, J. S.; Tang, T. T.; Post, L.; Huang, B.; Santisteban, P.; Goodarzi, H.; Bandyopadhyay, S.; Kuo, C. J.; Roose, J. P.; Wu, W.; Blakely, C. M.; Roth, J. A.; Bivona, T. G.
10.1101/2021.10.23.465573 — cancer biology — Posted on 2021-10-24
967 Single-cell transcriptional analysis of the immune tumour microenvironment during myeloma disease evolution
Croucher, D. C.; Richards, L. M.; Waller, D.; Li, Z.; Huang, X. F.; Chesi, M.; Bergsagel, P. L.; Sebag, M.; Pugh, T. J.; Trudel, S.
10.1101/2021.10.22.464971 — cancer biology — Posted on 2021-10-24
970 Human coronaviruses disassemble processing bodies
Kleer, M.; Mulloy, R. P.; Robinson, C.-A.; Bui-Marinos, M.; Castle, E. L.; Banerjee, A.; Mubareka, S.; Mossman, K.; Corcoran, J. A.
10.1101/2020.11.08.372995 — microbiology — Posted on 2021-10-24
971 Inactivation of SARS Coronavirus 2 and COVID-19 patient samples for contemporary immunology and metabolomics studies
Eddins, D. J.; Bassit, L. C.; Chandler, J.; Haddad, N. S.; Musall, K.; Yang, J.; Kosters, A.; Dobosh, B. S.; Hernandez, M. R.; Ramonell, R. P.; Tirouvanziam, R. M.; Lee, F. E.-H.; Zandi, K.; Schinazi, R. F.; Ghosn, E.
10.1101/2021.10.22.465481 — microbiology — Posted on 2021-10-24
972 Nanoscopic resolution within a single imaging frame
Torres, E.; Pinto, R.; Linares, A.; Martinez, D.; Abonza, V.; Brito-Alarcon, E.; Calcines-Cruz, C.; Galindo, G.; Torres, D.; Jablonski, M.; Torres-Martinez, H. H.; Martinez, J. L.; Hernandez, H. O.; Ocelotl, J.; Garces, Y.; Barchi, M.; Dubrovsky, J. G.; Darszon, A.; Buffone, M.; Rodriguez, R.; Rendon-Mancha, J. M.; Wood, C.; Hernandez, A.; Krapf, D.; Crevenna, A. H.; Guerrero, A.
10.1101/2021.10.17.464398 — cell biology — Posted on 2021-10-24
974 Brain charts for the human lifespan
Bethlehem, R. A. I.; Seidlitz, J.; White, S. R.; Vogel, J. W.; Anderson, K. M.; Adamson, C.; Adler, S.; Alexopoulos, G. S.; Anagnostou, E.; Areces-Gonzalez, A.; Astle, D. E.; Auyeung, B.; Ayub, M.; Ball, G.; Baron-Cohen, S.; Beare, R.; Bedford, S. A.; Benegal, V.; Beyer, F.; Bin Bae, J.; Blangero, J.; Blesa Cabez, M.; Boardman, J. P.; Borzage, M.; Bosch-Bayard, J. F.; Bourke, N.; Calhoun, V. D.; Chakravarty, M. M.; Chen, C.; Chertavian, C.; Chetelat, G.; Chong, Y. S.; Cole, J. H.; Corvin, A.; Costantino, M.; Courchesne, E.; Crivello, F.; Cropley, V. L.; Crosbie, J.; Crossley, N.; Delarue, M.;
10.1101/2021.06.08.447489 — neuroscience — Posted on 2021-10-24
979 Excessive fetal growth affects HSC quiescence maintenance through epigenetic programming of EGR1 transcriptional network
Pelletier, A.; Carrier, A.; Zhao, Y.; Canouil, M.; Derhourhi, M.; Durand, E.; Berberian-Ferrato, L.; Greally, J.; Hughes, F.; Froguel, P.; Bonnefond, A.; Delahaye, F.
10.1101/2021.10.22.465419 — genomics — Posted on 2021-10-24
984 Previously uncharacterized rectangular bacteria in the dolphin mouth
Dudek, N. K.; Galaz-Montoya, J. G.; Shi, H.; Mayer, M.; Danita, C.; Celis, A. I.; Wu, G.-H.; Behr, B.; Huang, K. C.; Chiu, W.; Relman, D. A.
10.1101/2021.10.23.465578 — microbiology — Posted on 2021-10-24
985 Photoprotection is regulated by light-independent CO2 availability
Ruiz-Sola, M. A.; Flori, S.; Yuan, Y.; Villain, G.; Sanz-Luque, E.; Redekop, P.; Tokutsu, R.; Küken, A.; Tsichla, A.; Kepesidis, G.; Allorent, G.; Arend, M.; Iacono, F.; Finazzi, G.; Hippler, M.; Nikoloski, Z.; Minagawa, J.; Grossman, A. R.; Petroutsos, D.
10.1101/2021.10.23.465040 — plant biology — Posted on 2021-10-24
988 Genomic insights into variation in thermotolerance between hybridizing swordtail fishes
Payne, C.; Bovio, S.; Powell, D.; Gunn, T.; Banerjee, S.; Grant, V.; Rosenthal, G.; Schumer, M.
10.1101/2021.10.22.465484 — evolutionary biology — Posted on 2021-10-24
989 Molecular basis of ocean acidification sensitivity and adaptation in Mytilus galloprovincialis
Kapsenberg, L.; Bitter, M. C.; Miglioli, A.; Pelejero, C.; Gattuso, J.-P.; Dumollard, R.
10.1101/2021.10.23.465493 — ecology — Posted on 2021-10-24
990 Flexible neural coding in sensory, parietal, and frontal cortices during goal-directed virtual navigation
Noel, J.-P.; Balzani, E.; Avila, E.; Lakshminarasimhan, K.; Bruni, S.; Alefantis, P.; Savin, C.; Angelaki, D.
10.1101/2021.10.22.465526 — neuroscience — Posted on 2021-10-24
991 Optimal confidence for unaware visuomotor deviations
Pereira, M.; Skiba, R.; Cojan, Y.; Vuilleumier, P.; Begue, I.
10.1101/2021.10.22.465492 — neuroscience — Posted on 2021-10-24
992 Two structurally different oomycete MAMPs induce distinctive plant immune responses.
Monjil, M. S.; Kato, H.; Matsuda, K.; Suzuki, N.; Tenhiro, S.; Camagna, M.; Suzuki, T.; Tanaka, A.; Terauchi, R.; Sato, I.; Chiba, S.; Kawakita, K.; Ojika, M.; Takemoto, D.
10.1101/2021.10.22.465218 — plant biology — Posted on 2021-10-24
993 RAGE antagonist peptide mitigates AGE-mediated endothelial hyperpermeability and accumulation of glycoxidation products in human ascending aortas and in a murine model of aortic aneurysm
Camillo, C.; Abramov, A.; Allen, P. M.; Castillero, E.; Roberts, E.; Xue, Y.; Frasca, A.; Moreno, V.; Kurade, M.; Robinson, K.; Spiegel, D.; LaPar, D.; Grau, J. B.; Assoian, R.; Bavaria, J. E.; Takayama, H.; Ferrari, G.
10.1101/2021.10.22.465199 — physiology — Posted on 2021-10-24
994 Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension
Regan, J. C.; Lu, Y.-X.; Urena, E.; Meilenbrock, R.; Catterson, J. H.; Kissler, D.; Partridge, L.
10.1101/2021.10.22.465415 — physiology — Posted on 2021-10-24
995 Wiring multiple microenvironment proteomes uncovers the biology in head and neck cancer
Busso-Lopes, A. F.; Rivera, C.; Neves, L. X.; Granato, D. C.; Patroni, F. M.; Mazo, T. R.; Normando, A. G. C.; Domingues, R. R.; Heberle, H.; Pretti, M. A.; Mello, B. P.; Rodrigues, A. N.; Lacerda, P. A.; Galdino, N. A.; Gollob, K. J.; Medina, T. S.; Cervigne, N. K.; Prado-Ribeiro, A. C.; Brandao, T. B.; Villa, L. L.; Uno, M.; Boroni, M.; Kowalski, L. P.; Gonzalez-Arriagada, W.; Paes Leme, A. F.
10.1101/2021.10.22.465341 — cancer biology — Posted on 2021-10-24
996 Shared hotspot mutations in spontaneously arising cancers position dog as an unparalleled comparative model for precision therapeutics
Rodrigues, L. C.; Watson, J.; Feng, Y.; Lewis, B.; Harvey, G.; Post, G.; MEGQUIER, K. J.; Lambert, L.; Miller, A.; Lopes, C.; Zhao, S.
10.1101/2021.10.22.465469 — cancer biology — Posted on 2021-10-24
997 A Developmentally Prometastatic Niche to Hepatoblastoma in Neonatal Liver mediated by the Cxcl1/Cxcr2 Axis
Fan, L.; Pan, Q.; Yang, W.; Koo, S. C.; Tian, C.; Li, L.; Lu, M.; Brown, A.; Ju, B.; Easton, J.; Ranganathan, S.; Shin, S.; Bondoc, A.; Yang, J. J.; Yu, J.; Zhu, L.
10.1101/2021.10.22.465518 — cancer biology — Posted on 2021-10-24
998 Classical Mathematical Models for Prediction of Response to Chemotherapy and Immunotherapy
Ghaffari Laleh, N.; Loeffler, C. M. L.; Grajek, J.; Stankova, K.; Pearson, A. T.; Muti, H. S.; Trautwein, C.; Enderling, H.; Poleszczuk, J.; Kather, J. N.
10.1101/2021.10.23.465549 — cancer biology — Posted on 2021-10-24
999 The mechanosensitive TRPV2 calcium channel controls melanoma invasiveness and metastatic potential.
Shoji, K. F.; Bayet, E.; Le Devedec, D.; Mallavialle, A.; Marionneau-lambot, S.; Leverrier-Penna, S.; Rambow, F.; Perret, R.; Joussaume, A.; Viel, R.; Fautrel, A.; Khammari, A.; Constantin, B.; Tartare-Deckert, S.; Penna, A.
10.1101/2021.10.22.465391 — cancer biology — Posted on 2021-10-24
1002 End-to-end learning of multiple sequence alignments with differentiable Smith-Waterman
Petti, S.; Bhattacharya, N.; Rao, R.; Dauparas, J.; Thomas, N.; Zhou, J.; Rush, A. M.; Koo, P. K.; Ovchinnikov, S.
10.1101/2021.10.23.465204 — bioinformatics — Posted on 2021-10-24
1010 Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution
Akil, C.; Ali, S.; Tran, L. T.; Gaillard, J.; Li, W.; Hayashida, K.; Hirose, M.; Kato, T.; Oshima, A.; Fujishima, K.; Blanchoin, L.; Narita, A.; Robinson, R. C.
10.1101/2021.10.22.465531 — evolutionary biology — Posted on 2021-10-24
1012 Disentangling the role of poultry farms and wild birds in the spread of highly pathogenic avian influenza virus H5N8 in Europe
Guinat, C.; Valenzuela Agui, C.; Vaughan, T. G.; Scire, J.; Pohlmann, A.; Staubach, C.; King, J.; Swieton, E.; Dan, A.; Cernikova, L.; Ducatez, M. F.; Stadler, T.
10.1101/2021.10.22.465255 — ecology — Posted on 2021-10-24
1014 The epidemiology and genomics of a virulent emerging fungal pathogen in an Australian reptile
Class, B.; Powell, D.; Terraube, J.; Albery, G. F.; Delme, C.; Bansal, S.; Frere, C.
10.1101/2021.10.22.465237 — ecology — Posted on 2021-10-24
1015 A Segmentation-Free Machine Learning Architecture for Immune Landscape Phenotyping in Solid Tumors by Multichannel Imaging
Sultan, S.; Gorris, M. A. J.; van der Woude, L. L.; Buytenhuijs, F.; Martynova, E.; van Wilpe, S.; Verrijp, K.; Figdor, C. G.; de Vries, I. J. M.; Textor, J.
10.1101/2021.10.22.464548 — immunology — Posted on 2021-10-24
1016 Verbena officinalis L. regulates killing efficiency of natural killer cells
Shao, R.; Zhou, X.; Zhao, R.; Yanamandra, A. K.; Xing, Z.; Dai, X.; Zhang, H.; Wang, Y.; Wang, Y.; Qu, B.
10.1101/2021.10.22.465498 — immunology — Posted on 2021-10-24
1017 Clostridioides difficile infection increases circulating p-cresol levels and dysregulates brain dopamine metabolism: linking gut-brain axis to autism and other neurologic disorders?
A. Vinithakumari, A.; Padhi, P.; G. Hernandez, B.; Je-Han Lin, S.; Dunkerson-Kurzhumov, A.; Showman, L.; Breitzman, M.; Stokes, C.; Sulaiman, Y.; Tangudu, C.; Kuttappan, D. A.; Muyyarikkandy, M. S.; Phillips, G. J.; Anantharam, V.; Perera, A.; Sponseller, B.; Kanthasamy, A.; Mooyottu, S.
10.1101/2021.10.22.465382 — neuroscience — Posted on 2021-10-24
1018 Generating accurate 3D gaze vectors using synchronized eye tracking and motion capture
Stone, S. A.; Boser, Q. A.; Dawson, T. R.; Vette, A. H.; Hebert, J. S.; Pilarski, P. M.; Chapman, C. S.
10.1101/2021.10.22.465332 — neuroscience — Posted on 2021-10-24
1021 Fatigue induces behavioural improvements in the unfatigued hand via altered functional connectivity and neurochemicals in cortical motor areas
Andrushko, J. W.; Levenstein, J. M.; Zich, C.; Edmond, E. C.; Campbell, J.; Clarke, W. T.; Emir, U.; Farthing, J. P.; Stagg, C. J.
10.1101/2021.10.23.464569 — neuroscience — Posted on 2021-10-24
1024 Distribution of multi-unit pitch responses recorded intracranially from human auditory cortex
Berger, J. I.; Gander, P. E.; Kikuchi, Y.; Kumar, S.; Kovach, C. K.; Oya, H.; Kawasaki, H.; Howard, M. A.; Griffiths, T. D.
10.1101/2021.10.22.465330 — neuroscience — Posted on 2021-10-24
1025 Visual occipito-temporal sensitivity to digits through elementary school
Fraga-Gonzalez, G.; Di Pietro, S. V.; Pleisch, G.; Neuenschwander, J.; Walitza, S.; Brandeis, D.; Karipidis, I. I.; Brem, S.
10.1101/2021.10.22.465440 — neuroscience — Posted on 2021-10-24
1027 Quantitative fragmentomics allow affinity mapping of interactomes
Gogl, G.; Zambo, B.; Kostmann, C.; Cousido-Siah, A.; Morlet, B.; Durbesson, F.; Negroni, L.; Eberling, P.; Jane, P.; Nomine, Y.; Zeke, A.; Ostergaard, S.; Monsellier, E.; Vincentelli, R.; Trave, G.
10.1101/2021.10.22.465449 — systems biology — Posted on 2021-10-24
1031 Polar lipids are linked to nanoparticles in xylem sap of temperate angiosperm species
Guan, X.; Schenk, H. J.; Roth, M. R.; Welti, R.; Werner, J.; Kaack, L.; Trabi, C. L.; Jansen, S.
10.1101/2021.10.22.465462 — plant biology — Posted on 2021-10-24
1032 The behavioral effects of gestational and lactational benzopyrene exposure vary by sex and genotype in mice with differences at the Ahr and Cyp1a2 loci
Honaker, A.; Kyntchev, A.; Foster, E.; Clough, K.; Asiedu, E.; Feltner, M.; Ferguson, V.; Forrest, P. T.; Sene, Y.; Mullaguru, J.; Niang, M. D.; Perry, C.; Curran, C. P.
10.1101/2021.10.22.465510 — pharmacology and toxicology — Posted on 2021-10-24
1033 Loss of epigenetic regulation disrupts lineage integrity, reactivatesmultipotency and promotes breast cancer
Langille, E.; Al-Zahrani, K. N.; Ma, Z.; Malik, A.; Loganathan, S. K.; Trcka, D.; Liu, J.; Kozma, K.; Tsai, R.; Teng, K.; Espin, R.; Barutcu, S.; Nguyen, T.; Bremner, R.; Jackson, H. W.; Knudsen, E.; Bader, G.; Egan, S.; Pujana, M. A.; Wrana, J.; Wahl, G. M.; Schramek, D.
10.1101/2021.10.22.465428 — cancer biology — Posted on 2021-10-24
1034 Extrachromosomal Amplification of Human Papillomavirus Episomes as a Mechanism of Cervical Carcinogenesis
Rossi, N. M.; Dai, J.; Xie, Y.; Lou, H.; Boland, J. F.; Yeager, M.; Orozco, R.; Alvirez, E.; Mirabello, L.; Gharzouzi, E.; Dean, M.
10.1101/2021.10.22.465367 — cancer biology — Posted on 2021-10-24
1036 Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics
Johri, S.; Bi, K.; Titchen, B. M.; Fu, J.; Conway, J.; Crowdis, J. P.; Volkes, N. I.; Fan, Z.; Fong, L.; Park, J.; Liu, D.; He, M. X.; Van Allen, E.
10.1101/2021.10.22.465130 — bioinformatics — Posted on 2021-10-24
1037 High-precision spatial analysis of mouse courtship vocalization behavior reveals sex and strain differences
Oliveira-Stahl, G.; Farboud, S.; Sterling, M. L.; Heckman, J. J.; Raalte, B. v.; Lenferink, D.; Stam, A. v. d.; Smeets, C. J. L. M.; Fisher, S. E.; Englitz, B.
10.1101/2021.10.22.464496 — animal behavior and cognition — Posted on 2021-10-24
1038 transferGWAS: GWAS of images using deep transfer learning
Kirchler, M.; Konigorski, S.; Norden, M.; Meltendorf, C.; Kloft, M.; Schurmann, C.; Lippert, C.
10.1101/2021.10.22.465430 — genetics — Posted on 2021-10-24
1039 Eurasian lynx populations in Western Europe: What prospects for the next 50 years?
Bauduin, S.; Germain, E.; Zimmermann, F.; Idelberger, S.; Herdtfelder, M.; Heurich, M.; Kramer-Schadt, S.; Duchamp, C.; Drouet-Hoguet, N.; Morand, A.; Blanc, L.; Charbonnel, A.; Gimenez, O.
10.1101/2021.10.22.465393 — ecology — Posted on 2021-10-24
1044 In-vitro cellular reprogramming to model gonad development and its disorders
Gonen, N.; Eozenou, C.; Mitter, R.; Bernardo, A.; Chervova, A.; Frachon, E.; Commere, P.-H.; Mazen, I.; Gobaa, S.; McElreavey, K.; Lovell-Badge, R.; Bashamboo, A.
10.1101/2021.10.22.465384 — developmental biology — Posted on 2021-10-24
1045 Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2
Feng, J.; Dong, X.; DeCosta, A.; Su, Y.; Angrisano, F.; Sala, K. A.; Blagborough, A. M.; Lu, C.; Springer, T. A.
10.1101/2021.10.22.465389 — immunology — Posted on 2021-10-24
1048 Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1
Tejwani, L.; Ravindra, N. G.; Nguyen, B.; Luttik, K.; Lee, C.; Gionco, J.; Kim, K.; Yoon, J.; Haidery, F.; Ro, H.; Ni, L.; Orr, H.; Ranum, L.; Shakkottai, V.; Faust, P. L.; van Dijk, D.; Lim, J.
10.1101/2021.10.22.465444 — neuroscience — Posted on 2021-10-24
1049 Oxytocin reduces interoceptive influences on empathy-for-pain in the anterior insula
Betka, S. J. A.; Gould Van Praag, C.; Rae, C.; Pfeiffer, G.; Sequeira, H.; Duka, D.; Critchley, H.
10.1101/2021.10.22.465431 — neuroscience — Posted on 2021-10-24
1052 Spatiotemporal transcriptome at single-cell resolution reveals key radial glial cell population in axolotl telencephalon development and regeneration
Wei, X.; Fu, S.; Li, H.; Liu, Y.; Wang, S.; Feng, W.; Yang, Y.; Liu, X.; Zeng, Y.-Y.; Cheng, M.; Lai, Y.; Qiu, X.; Wu, L.; Zhang, N.; Jiang, Y.; Xu, J.; Su, X.; Peng, C.; Han, L.; Lou, W. P.-K.; Liu, C.; Yuan, Y.; Ma, K.; Yang, T.; Pan, X.; Gao, S.; Chen, A.; Esteban, M. A.; Yang, H.; Wang, J.; Fan, G.; Liu, L.; Chen, L.; Xu, X.; Fei, J.-F.; Gu, Y.
10.1101/2021.10.23.465550 — developmental biology — Posted on 2021-10-24
1053 Neural knowledge assembly in humans and deep networks
Nelli, S. M.; Braun, L.; Dumbalska, T.; Saxe, A.; Summerfield, C.
10.1101/2021.10.21.465374 — neuroscience — Posted on 2021-10-23
1054 The many layers of BOLD. On the contribution of different vascular compartments to laminar fMRI.
Schellekens, W.; Bhogal, A. A.; Roefs, E. C. A.; Baez-Yanez, M. G.; Siero, J. C. W.; Petridou, N.
10.1101/2021.10.21.465359 — neuroscience — Posted on 2021-10-23
1055 Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate slows aging in mice
Jiang, Z.; Wang, J.; Imai, D.; Snider, T.; Mangalindan, R.; Zhu, L.; Morton, J.; Salmon, A. B.; Wezeman, J.; Klug, J.; Hu, J.; Menon, V.; Marka, N.; Neidernhofer, L.; Ladiges, W. C.
10.1101/2021.10.21.465380 — systems biology — Posted on 2021-10-23
1058 Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats
Oka, K.; Fujioka, S.; Kawamura, Y.; Komohara, Y.; Chujo, T.; Sekiguchi, K.; Yamamura, Y.; Oiwa, Y.; Omamiuda-Ishikawa, N.; Komaki, S.; Sutoh, Y.; Sakurai, S.; Tomizawa, K.; Bono, H.; Shimizu, A.; Araki, K.; Yamamoto, T.; Yamada, Y.; Oshiumi, H.; Miura, K.
10.1101/2021.10.21.465383 — cancer biology — Posted on 2021-10-23
1059 Real-Time Structure Search and Structure Classification for AlphaFold Protein Models
Aderinwale, T.; Bharadwaj, V.; Christoffer, C.; Terashi, G.; Zhang, Z.; Jahandideh, R.; Kagaya, Y.; Kihara, D.
10.1101/2021.10.21.465371 — bioinformatics — Posted on 2021-10-23
1061 Crustacean cardiac ganglion model reveals constraints on morphology and conductances
Dopp, D. S.; Samarth, P. S.; Wang, J. S.; Kick, D. R.; Schulz, D. J.; Nair, S. S.
10.1101/2021.10.21.464612 — neuroscience — Posted on 2021-10-23
1062 Social mobility and biological aging among older adults in the United States
Graf, G. H.-J.; Zhang, Y.; Domingue, B. W.; Harris, K. M.; Kothari, M.; Kwon, D.; Muennig, P. A.; Belsky, D. W.
10.1101/2021.10.19.465042 — physiology — Posted on 2021-10-23
1064 NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses
Leal, T. P.; Furlan, V. C.; Gouveia, M. H.; Duarte, J. M. S.; Fonseca, P. A.; Tou, R.; Scliar, M. O.; Araujo, G. S.; Zolini, C.; Peixoto, M. G. C. D.; Lima-Costa, M. F.; Gilman, R. H.; Tarazona-Santos, E.; Rodrigues, M. R.
10.1101/2021.10.21.465343 — bioinformatics — Posted on 2021-10-23
1065 Single Pulse Heating of Nanoparticle Array for Biological Applications
XIE, C.; Kang, P.; Cazals, J.; Castelan, O. M.; Randrianalisoa, J.; Qin, Z.
10.1101/2021.10.21.465356 — bioengineering — Posted on 2021-10-23
1067 A multi-variant recall-by-genotype study of the metabolomic signature of body mass index
Fang, S.; Wade, K. H.; Hughes, D. A.; FitzGibbon, S.; Yip, V.; Timpson, N. J.; Corbin, L. J.
10.1101/2021.10.21.465319 — genetics — Posted on 2021-10-23
1069 "Neighbourhood watch" model: embryonic epiblast cells assess positional information in relation to their neighbours
Lee, H. C.; Hastings, C.; de Oliveira, N. M. M.; Perez-Carrasco, R.; Page, K. M.; Wolpert, L.; Stern, C. D.
10.1101/2021.04.22.440894 — developmental biology — Posted on 2021-10-23
1072 Impacts of dams on freshwater turtles: a global review to identify conservation solutions
Barcenas-Garcia, A.; Michalski, F.; Morgan, W. H.; Smith, R. K.; Sutherland, W. J.; Gibbs, J. P.; Norris, D.
10.1101/2021.10.21.465338 — zoology — Posted on 2021-10-23
1074 The p53-p21 axis plays a central role in lymphatic homeostasis and disease
Mylavarapu, R.; Kulikauskas, M.; Dierkes, C.; Sobhani, N.; Finlon, J.; Mangette, M.; Stevens, W.; Arbab, F.; Box, N. F.; Lovell, M.; Muley, A.; Shawber, C. J.; Tamburini, B.; Kiefer, F.; Terzian, T.
10.1101/2020.03.18.992784 — developmental biology — Posted on 2021-10-23
1077 Circadian programming of the ellipsoid body sleep homeostat in Drosophila
Andreani, T.; Rosensweig, C.; Sisobhan, S.; Ogunlana, E.; Kath, B.; Allada, R.
10.1101/2021.10.22.465404 — neuroscience — Posted on 2021-10-23
1078 The missing pathway in current visuospatial processing models
Beyh, A.; Dell'Acqua, F.; Cancemi, D.; De Santiago Requejo, F.; ffytche, D.; Catani, M.
10.1101/2021.06.08.442147 — neuroscience — Posted on 2021-10-23
1079 A connectomic study of a petascale fragment of human cerebral cortex
Shapson-Coe, A.; Januszewski, M.; Berger, D. R.; Pope, A.; Wu, Y.; Blakely, T.; Schalek, R. L.; Li, P. H.; Wang, S.; Maitlin-Shepard, J.; Karlupia, N.; Dorkenwald, S.; Sjostedt, E.; Leavitt, L.; Lee, D.; Bailey, L.; Fitzmaurice, A.; Kar, R.; Field, B.; Wu, H.; Wagner-Carena, J.; Aley, D.; Lau, J.; Lin, Z.; Wei, D.; Pfister, H.; Peleg, A.; Jain, V.; Lichtman, J. W.
10.1101/2021.05.29.446289 — neuroscience — Posted on 2021-10-23
1081 Spatiotemporal transcriptome at single-cell resolution reveals key radial glial cell population in axolotl telencephalon development and regeneration
Wei, X.; Fu, S.; Li, H.; LIU, Y.; Wang, S.; Feng, W.; Yang, Y.; Liu, X.; Zeng, Y. Y.; Cheng, M.; Lai, Y.; Qiu, X.; Wu, L.; Zhang, N.; Jiang, Y.; Xu, J.; Su, X.; Peng, C.; Han, L.; Lou, W. P.-K.; Liu, C.; Yuan, Y.; Ma, K.; Yang, T.; Pan, X.; Gao, S.; Chen, A.; Esteban, M. A.; Yang, H.; Wang, J.; Fan, G.; Liu, L.; Chen, L.; Xu, X.; Fei, F. J.; Gu, Y.
10.1101/2021.10.23.465550 — developmental biology — Posted on 2021-10-23
1084 A positively Tuned Voltage Indicator Reveals Electrical Correlates of Calcium Activity in the Brain
Evans, S. W.; Shi, D.; Chavarha, M.; Plitt, M. H.; Taxidis, J.; Madruga, B.; Van Keulen, S. C.; Pang, M.; Su, S.; Hwang, F.-J.; Zhang, G.; Reese, A.; Pradhan, L.; Fan, J. L.; Lee, S.; Liu, Y.; Suomivuori, C.-M.; Jiang, D.; Negrean, A.; Wang, S.; Ji, N.; Clandinin, T.; Dror, R.; Bi, G. G.; Makinson, C. D.; Golshani, P.; Giocomo, L. M.; Losonczy, A.; Ding, J. B.; Lin, M. Z.
10.1101/2021.10.21.465345 — neuroscience — Posted on 2021-10-23
1085 Regulation of Neuroendocrine Plasticity by the RNA-Binding Protein ZFP36L1
Chen, H.-Y.; Durmaz, Y. T.; Li, Y.; Sabet, A. H.; Vajdi, A.; Denize, T.; Walton, E.; Doench, J. G.; Mahadevan, N. R.; Losman, J. A.; Barbie, D. A.; Tolstorukov, M. Y.; Rudin, C. M.; Sen, T.; Signoretti, S.; Oser, M.
10.1101/2021.10.22.465501 — cancer biology — Posted on 2021-10-23
1086 Melanoma Addiction to GCDH is Mediated by NRF2 Tumor Suppressor Function
Verma, S.; Crawford, D.; Khateb, A.; Feng, Y.; Sergienko, E.; Pathria, G.; Ma, C.-T.; Olson, S. H.; Scott, D. A.; Murad, R.; Ruppin, E.; Jackson, M.; Ronai, Z. A.
10.1101/2021.10.22.465495 — cancer biology — Posted on 2021-10-23
1088 Zika virus infection drives epigenetic modulation of immunity by the histone acetyltransferase CBP of Aedes aegypti
Amarante, A. d. M.; da Silva, I. C. d. A.; Vicentino, A. R. R.; Carneiro, V. C.; Pinto, M. d. A.; Higa, L. M.; Moharana, K. C.; da Cunha, O. A. T.; Venancio, T. M.; de Oliveira, P. L.; Fantappie, M. R.
10.1101/2021.10.22.463187 — molecular biology — Posted on 2021-10-23
1091 Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine.
Sheikh, A.; Wangdi, T.; Vickers, T. J.; Aaron, B.; Palmer, M. P.; Miller, M.; Kim, S.; Herring, C.; Simoes, R.; Crainic, J. A.; Gildersleeve, J.; van der Post, S.; Hansson, G. C.; Fleckenstein, J. M.
10.1101/2021.10.22.465536 — microbiology — Posted on 2021-10-23
1092 Genotype-Phenotype Correlation of T Cell Subtypes Reveals Senescent and Cytotoxic Genes in Alzheimer's Disease
Dressman, D.; Buttrick, T.; Cimpean, M.; Bennett, D.; Menon, V.; Bradshaw, E. M.; Vardarajan, B.; Elyaman, W.
10.1101/2021.10.19.464914 — immunology — Posted on 2021-10-23
1094 PermaPhosSer: autonomous synthesis of functional, permanently phosphorylated proteins
Zhu, P.; Franklin, R.; Vogel, A.; Stanisheuski, S.; Reardon, P.; Beckman, J. S.; Karplus, P. A.; Mehl, R. A.; Cooley, R. B.
10.1101/2021.10.22.465468 — synthetic biology — Posted on 2021-10-23
1095 PRMT1 regulates EGFR and Wnt signaling pathways and is a promising target for combinatorial treatment of breast cancer
Suresh, S.; Huard, S.; Brisson, A.; Nemati, F.; Poulard, C.; Ye, M.; Martel, E.; Reyes, C.; Silvestre, D. C.; Meseure, D.; Nicolas, A.; Gentien, D.; Le Romancer, M.; Decaudin, D.; Roman-Roman, S.; Dubois, T.
10.1101/2021.10.22.465320 — cancer biology — Posted on 2021-10-23
1097 Cancer cell-autonomous cGAS-STING response confers drug resistance
Lv, Q.-M.; Wang, S.-Y.; Lei, H.-M.; Zhang, K.-R.; Tang, Y.-B.; Shen, Y.; Lu, L.-M.; Chen, H.-Z.; Zhu, L.
10.1101/2021.10.23.465546 — cancer biology — Posted on 2021-10-23
1099 FABP7 Binds to Fatty Acid Micelles: Implications for Lipid Transport
Lenz, S.; Bodnariuc, I.; Renaud-Young, M.; Shandro, T. M.; MacCallum, J. L.
10.1101/2021.10.22.465361 — biophysics — Posted on 2021-10-23
1100 Novel regulation of the transcription factor ZHX2 by N-terminal methylation
Conner, M. M.; Parker, H. V.; Falcone, D. R.; Chung, G.; Schaner Tooley, C.
10.1101/2021.10.22.465472 — biochemistry — Posted on 2021-10-23
1101 Potential genetic robustness of Prnp and Sprn double knockout mouse embryos towards ShRNA-lentiviral inoculation
Rau, A.; Passet, B.; Castille, J.; Asset, A.; Lecardonnel, J.; Moroldo, M.; Jaffrezic, F.; Laloë, D.; Moazami-Goudarzi, K.; Vilotte, J.-L.
10.1101/2021.10.22.465458 — genomics — Posted on 2021-10-23
1103 A highly endemic area of Echinococcus multilocula is identified through a comparative re-assessment of prevalence in red fox (Vulpes vulpes), Alto Adige (Italy: 2019-2020)
Obber, F.; Celva, R.; Da Rold, G.; Trevisiol, K.; Ravagnan, S.; Danesi, P.; Cenni, L.; Rossi, C.; Bonato, P.; Capello, K.; Hauffe, H. C.; Massolo, A.; Cassini, R.; Benvenuti, V.; Agreiter, A.; Righetti, D.; Ianniello, M.; Dellamaria, D.; Capelli, G.; Citterio, C. V.
10.1101/2021.10.22.465400 — molecular biology — Posted on 2021-10-23
1107 Cytosolic Sensor of Bacterial Lipopolysaccharide in Human Macrophages
Rojas-Lopez, M.; Zajac, A. S.; Wood, T. E.; Miller, K. A.; Gil Marques, M. L.; Hachey, A. C.; Kharbanda, V.; Goldberg, M. B.
10.1101/2021.10.22.465470 — microbiology — Posted on 2021-10-23
1108 Dynamic Cell Imaging: application to the diatom Phaeodactylum tricornutum under environmental stresses
Bey, H.; Charton, F.; Cruz de Carvalho, H.; Liu, S.; Dorrell, R. G.; Bowler, C.; Boccara, C.; Boccara, m.
10.1101/2021.10.22.465453 — microbiology — Posted on 2021-10-23
1110 Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand
Liu, Z. S.-J.; Sattabongkot, J.; White, M.; Chotirat, S.; Kumpitak, C.; Takashima, E.; Harbers, M.; Tham, W.-H.; Healer, J.; Chitnis, C. E.; Tsuboi, T.; Mueller, I.; Longley, R. J.
10.1101/2021.10.21.464164 — microbiology — Posted on 2021-10-23
1113 Generative neural networks separate common and specific transcriptional responses
Lee, A. J.; Mould, D. L.; Crawford, J.; Hu, D.; Powers, R. K.; Doing, G.; Costello, J. C.; Hogan, D. A.; Greene, C. S.
10.1101/2021.05.24.445440 — bioinformatics — Posted on 2021-10-23
1118 Developmental Dynamics of RNA Translation in the Human Brain
Duffy, E. E.; Finander, B.; Choi, G.; Carter, A. C.; Pritisanac, I.; Alam, A.; Luria, V.; Karger, A.; Phu, W.; Sherman, M. A.; Assad, E. G.; Khitun, A.; Crouch, E. E.; Ganesh, S.; Berger, B.; Sestan, N.; O'Donnell-Luria, A.; Huang, E. J.; Griffith, E. C.; Forman-Kay, J. D.; Moses, A.; Kalish, B. T.; Greenberg, M. E.
10.1101/2021.10.22.465170 — neuroscience — Posted on 2021-10-23
1123 S1P controls endothelial sphingolipid homeostasis via ORMDL
Sasset, L.; Chowdhury, K. H.; Manzo, O. L.; Rubinelli, L.; Konrad, C.; Maschek, J. A.; Manfredi, G.; Holland, W. L.; Di Lorenzo, A.
10.1101/2021.10.22.465503 — cell biology — Posted on 2021-10-23
1124 Higher synaptic threshold for NMDA spike generation in human neurons
Testa-Silva, G.; Rosier, M.; Honnuraiah, S.; Guzulaitis, R.; Morello Megias, A.; French, C.; King, J.; Drummond, K.; Palmer, L. M.; Stuart, G. J.
10.1101/2021.10.22.465509 — neuroscience — Posted on 2021-10-23
1125 Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies
Banks, R. A.; Galstyan, V.; Lee, H. J.; Hirokawa, S.; Ierokomos, A.; Ross, T. D.; Bryant, Z.; Thomson, M.; Phillips, R.
10.1101/2021.10.22.465381 — biophysics — Posted on 2021-10-23
1127 Coordinated DNA and Histone Dynamics Drive Accurate Histone H2A.Z Exchange
Poyton, M. F.; Feng, X. A.; Ranjan, A.; Lei, Q.; Wang, F.; Zarb, J. S.; Louder, R. K.; Park, G.; Jo, M. H.; Ye, Z.; Liu, S.; Ha, T.; Wu, C.
10.1101/2021.10.22.465479 — biophysics — Posted on 2021-10-23
1132 The post-transcriptional regulation of TFs in immature motoneurons shapes the axon-muscle connectome
GUAN, W.; Bellemin, S.; Bouchet, M.; Venkatasubramanian, L.; Guillermin, C.; Laurencon, A.; Cherif, K.; Darmas, A.; Godin, C.; Urdy, S.; S. Mann, R.; Enriquez, J.
10.1101/2021.10.22.465474 — developmental biology — Posted on 2021-10-23
1133 Trap-TRAP, a versatile tool for tissue-specific translatomics in zebrafish
Corbacho, J.; Sanabria-Reinoso, E.; Fernandez-Minan, A.; Martinez-Morales, J. R.
10.1101/2021.10.22.465445 — developmental biology — Posted on 2021-10-23
1134 The Rpd3-complex regulates expression of multiple cell surface recycling factors in yeast
Amoiradaki, K.; Bunting, K. R.; Paine, K. M.; Hogg, K.; Ayre, J. E.; Laidlaw, K. M.; MacDonald, C.
10.1101/2021.10.22.465438 — cell biology — Posted on 2021-10-23
1137 Yersinia remodels epigenetic histone modifications in human macrophages
Bekere, I.; Huang, J.; Schnapp, M.; Rudolph, M.; Berneking, L.; Ruckdeschel, K.; Grundhoff, A.; Günther, T.; Fischer, N.; Aepfelbacher, M.
10.1101/2021.09.07.459276 — microbiology — Posted on 2021-10-23
1138 A vacuolar hexose transport is required for xylem development in the inflorescence stem of Arabidopsis.
Aubry, E.; Hoffmann, B.; Vilaine, F.; Gilard, F.; Klemens, P. A. W.; Guerard, F.; Gakiere, B.; Neuhaus, H. E.; Bellini, C.; Dinant, S.; Le Hir, R.
10.1101/2020.12.09.417345 — plant biology — Posted on 2021-10-23
1139 Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats
Mesnage, R.; Ibragim, M.; Mandrioli, D.; Falcioni, L.; Tibaldi, E.; Belpoggi, F.; Brandsma, I.; Bourne, E.; Savage, E.; Mein, C. A.; Antoniou, M. N.
10.1101/2021.04.12.439463 — pharmacology and toxicology — Posted on 2021-10-23
1140 Improving variant calling using population data and deep learning
Chen, N.-C.; Kolesnikov, A.; Goel, S.; Yun, T.; Chang, P.-C.; Carroll, A.
10.1101/2021.01.06.425550 — bioinformatics — Posted on 2021-10-22
1142 High Spatial Resolution MALDI Imaging Mass Spectrometry ofFresh-Frozen Bone
Good, C. J.; Neumann, E. K.; Butrico, C. E.; Cassat, J. E.; Caprioli, R. M.; Spraggins, J. M.
10.1101/2021.10.01.462831 — biochemistry — Posted on 2021-10-23
1143 A heterochromatic knob reducing the flowering time in maize
Carvalho, R. F.; Aguiar-Perecin, M. L. R.; Clarindo, W. R.; Fritsche Neto, R. F.; Mondin, M.
10.1101/2021.03.31.437909 — genetics — Posted on 2021-10-22
1146 Gliding motility of Plasmodium merozoites
Yahata, K.; Hart, M. N.; Davies, H.; Asada, M.; Templeton, T. J.; Treeck, M.; Moon, R. W.; Kaneko, O.
10.1101/2020.05.01.072637 — microbiology — Posted on 2021-10-22
1147 A homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium
Van Winkle, J. A.; Peterson, S. T.; Kennedy, E. A.; Wheadon, M. J.; Ingle, H.; Desai, C.; Rodgers, R.; Constant, D. A.; Wright, A. P.; Li, L.; Artyomov, M.; Lee, S.; Baldridge, M. T.; Nice, T. J.
10.1101/2021.06.02.446828 — immunology — Posted on 2021-10-23
1148 Neural correlates and determinants of approach-avoidance conflict in the prelimbic prefrontal cortex
Fernandez-Leon, J. A.; Engelke, D. S.; Aquino-Miranda, G.; Goodson, A.; Rasheed, M. N.; Do Monte, F. H.
10.1101/2021.05.27.445881 — neuroscience — Posted on 2021-10-22
1152 A curated collection of human vaccination response signatures
Smith, K. C.; Chawla, D. G.; Dhillon, B. K.; Ji, Z.; Vita, R.; van der Leest, E. C.; Weng, J. Y.; Tang, E.; Abid, A.; The Human Immunology Project Consortium (HIPC), ; Peters, B.; Hancock, R. E. W.; Floratos, A.; Kleinstein, S. H.
10.1101/2021.04.15.439017 — bioinformatics — Posted on 2021-10-22
1153 The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress.
Ribeyre, C.; Lebdy, R.; Patouillard, J.; Larroque, M.; Abou-Merhi, R.; Larroque, C.; Constantinou, A.
10.1101/669234 — cell biology — Posted on 2021-10-22
1160 High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications.
Murtha, A. N.; Kazi, M. I.; Schargel, R. D.; Cross, T.; Fihn, C.; Carlson, E. E.; Boll, J. M.; Dörr, T.
10.1101/2021.09.25.461800 — microbiology — Posted on 2021-10-22
1164 Dissociation of β2m from MHC Class I Triggers Formation of Noncovalent, Transient Heavy Chain Dimers
Dirscherl, C.; Loechte, S.; Hein, Z.; Kopicki, J.-D.; Harders, A. R.; Linden, N.; Weghuber, J.; Garcia-Alai, M.; Uetrecht, C.; Zacharias, M.; Piehler, J.; Lanzerstorfer, P.; Springer, S.
10.1101/2021.07.02.450866 — cell biology — Posted on 2021-10-22
1167 Modeling microRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
Marmol-Sanchez, E.; Cirera, S.; Zingaretti, L.; Jacobsen, M. J.; Ramayo-Caldas, Y.; Jorgensen, C. B.; Fredholm, M.; Cardoso, T. F.; Quintanilla, R.; Amills, M.
10.1101/2021.07.14.452370 — genomics — Posted on 2021-10-22
1170 Gramicidin S and Melittin - Potential anti-viral therapeutic peptides to treat SARS-CoV-2 infection
Enayathullah, M. G.; Parekh, Y.; Banu, S.; Ram, S.; Nagaraj, R.; Kiran Kumar, B.; Idris, M. M.
10.1101/2021.10.21.465254 — cell biology — Posted on 2021-10-22
1171 Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination
Zhou, R.; Wang, P.; Wong, Y.-C.; Xu, H.; Lau, S.-Y.; Liu, L.; Mok, B. W.-Y.; Peng, Q.; Liu, N.; Deng, S.; Tam, R. C.-Y.; Huang, H.; Zhang, A. J.; Zhou, D.; Zhou, B.; Chan, C.-Y.; Du, Z.; Yang, D.; Au, K.-K.; Yuen, K.-Y.; Chen, H.; Chen, Z.
10.1101/2021.10.21.465252 — immunology — Posted on 2021-10-22
1174 Proteomic analysis of mouse kidney tissue associates peroxisomal dysfunction with early diabetic kidney disease
Tserga, A.; Pouloudi, D.; Saulnier-Blache, J. S.; Stroggilos, R.; Theochari, I.; Gakiopoulou, H.; Mischak, H.; Zoidakis, J.; Schanstra, J. P.; Vlahou, A.; Makridakis, M.
10.1101/2021.10.21.465240 — systems biology — Posted on 2021-10-22
1175 Formulation of Dry Powders of Vaccines Containing MF59 or AddaVax by Thin-Film Freeze-Drying
AboulFotouh, K.; Uno, N.; Xu, H.; Moon, C.; Sahakijpijarn, S.; Christensen, D. J.; Davenport, G. J.; Cano, C.; Ross, T. M.; Williams, R. O.; Cui, Z.
10.1101/2021.10.21.465307 — pharmacology and toxicology — Posted on 2021-10-22
1178 Morphology and gene expression profiling provide complementary information for mapping cell state
Way, G. P.; Natoli, T.; Adeboye, A.; Litichevskiy, L.; Yang, A. X.; Lu, X.; Caicedo, J.; Cimini, B. A.; Karhohs, K.; Logan, D. J.; Rohban, M.; Kost-Alimova, M.; Hartland, K.; Bornholdt, M.; Chandrasekaran, N.; Haghighi, M.; Singh, S.; Subramanian, A.; Carpenter, A. E.
10.1101/2021.10.21.465335 — bioinformatics — Posted on 2021-10-22
1180 Complex population structure and haplotype patterns in Western Europe honey bee from sequencing a large panel of haploid drones
Wragg, D.; Eynard, S. E.; Basso, B.; Canale-Tabet, K.; Labarthe, E.; Bouchez, O.; Bienefeld, K.; Bienkowska, M.; Costa, C.; Gregorc, A.; Kryger, P.; Parejo, M.; Pinto, M. A.; Bidanel, J.-P.; Servin, B.; Le Conte, Y.; Vignal, A.
10.1101/2021.09.20.460798 — genetics — Posted on 2021-10-22
1182 Hydraulic synchrony of spawning sites amongst Earth's riverine fishes
O'Sullivan, A. M.; Morgan, A. M.; Newbury, R.; Linnansaari, T.; Kurylyk, B. L.; Helminen, J.; Wegscheider, B.; Johns, R. C.; Samways, K. M.; Alex, K. I.; Curry, A.; Cunjak, R. A.
10.1101/2021.10.21.464969 — ecology — Posted on 2021-10-22
1183 A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition
Soto-Feliciano, Y. M.; Sanchez-Rivera, F. J.; Perner, F.; Barrows, D. W.; Kastenhuber, E. R.; Ho, Y.-J.; Carroll, T.; Xiong, Y.; Soshnev, A.; Gates, L.; Beytagh, M. C.; Cheon, D.; Gu, S.; Liu, X. S.; Krivtsov, A. V.; Meneses, M.; de Stanchina, E.; Stone, R. M.; Armstrong, S. A.; Lowe, S. W.; Allis, C. D.
10.1101/2021.10.22.465184 — cancer biology — Posted on 2021-10-22
1185 Hybridisation and chloroplast capture between ancient Themeda triandra ecotypes in Australia
Dunning, L. T.; Oloffson, J. K.; Papadopulos, A. T.; Baleeiro, P. C.; Ntshangase, S.; Barker, N.; Jobson, R. W.
10.1101/2021.10.21.465284 — evolutionary biology — Posted on 2021-10-22
1188 Pupillometry and electroencephalography in the digit span task
Pavlov, Y. G.; Kasanov, D.; Kosachenko, A. I.; Kotyusov, A.; Busch, N. A.
10.1101/2021.10.21.465288 — neuroscience — Posted on 2021-10-22
1189 Use-dependent biases primarily originate from a contaminated motor plan
Tsay, J. S.; Kim, H. E.; Saxena, A.; Parvin, D. E.; Verstynen, T. V.; Ivry, R. B.
10.1101/2021.10.21.465112 — neuroscience — Posted on 2021-10-22
1191 Early detection of cerebrovascular pathology and protective antiviral immunity by MRI
Liu, L.; Dodd, S.; Hunt, R.; Pothayee, N.; Atanasijevic, T.; Bouraoud, N.; Maric, D.; Moseman, E. A.; Gossa, S.; McGavern, D.; Koretsky, A.
10.1101/2021.10.21.465276 — neuroscience — Posted on 2021-10-22
1195 A comprehensive benchmark for structural assessment in bipartite networks
Palazzi, M. J.; Lampo, A.; Sole-Ribalta, A.; Borge-Holthoefer, J.
10.1101/2021.10.21.465267 — ecology — Posted on 2021-10-22
1198 An in-vivo digital atlas of the spatially reliable cerebral vasculature in mice
Hinz, R.; Malekzadeh, M.; Peeters, L. M.; Vanreusel, V.; Verhoye, M.; Van der Linden, A.; Keliris, G. A.
10.1101/2021.10.21.465264 — neuroscience — Posted on 2021-10-22
1199 Visualization of Sympathetic Neural Innervation in Human White Adipose Tissue
Perdikari, A.; Cacciottolo, T.; Henning, E.; Mendes de Oliveira, E.; Keogh, J. M.; Farooqi, I. S.
10.1101/2021.10.21.465246 — neuroscience — Posted on 2021-10-22
1208 Sensing Local Field Potentials with a Directional and Scalable Depth Array: the DISC array
Abrego, A. M.; Khan, W.; Wright, C. E.; Prajapati, N.; Islam, M. R.; Bai, X.; Ghajar, M. H.; Tandon, N.; Seymour, J.
10.1101/2021.09.20.460996 — bioengineering — Posted on 2021-10-22
1210 Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
Robinson, P. S.; Thomas, L. E.; Abascal, F.; Jung, H.; Harvey, L.; West, H. D.; Olafsson, S.; Lee, B. C. H.; Coorens, T.; Lee-Six, H.; Butlin, L.; Lander, N.; Sanders, M. A.; Lensing, S.; Buczacki, S. J. A.; ten Hoopen, R.; Coleman, N.; Brunton-Sim, R.; Rushbrook, S.; Saeb-Parsy, K.; Lalloo, F.; Campbell, P. J.; Martincorena, I.; Sampson, J. R.; Stratton, M. R.
10.1101/2021.10.20.465093 — genomics — Posted on 2021-10-22
1211 Interpretable network-guided epistasis detection
Duroux, D.; Climente-Gonzales, H.; Azencott, C.-A.; Van Steen, K.
10.1101/2020.09.24.310136 — genetics — Posted on 2021-10-22
1214 Habitat loss exacerbates pathogen spread: An Agent-based model of avian influenza infection in migratory waterfowl
Yin, S.; Xu, Y.; de Jong, M. C. M.; Huisman, M. R. S.; Contina, A.; Prins, H. H. T.; Huang, Z. Y. X.; de Boer, W. F.
10.1101/2021.10.21.465250 — ecology — Posted on 2021-10-22
1215 High-resolution spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae
Wang, M.; Hu, Q.; Lv, T.; Wang, Y.; Lan, Q.; Tu, Z.; Xiang, R.; Wei, Y.; Han, K.; An, Y.; Cheng, M.; Xu, J.; Esteban, M.; Lu, H.; Li, W.; Zhang, S.; Chen, C.; Chen, W.; Li, Y.; Wang, X.; Xu, X.; Hu, Y.; Liu, L.
10.1101/2021.10.21.465301 — developmental biology — Posted on 2021-10-22
1216 Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis
Liu, C.; Li, R.; Li, Y.; Lin, X.; Wang, S.; Liu, Q.; Zhao, K.; Yang, X.; Shi, X.; Ma, Y.; Pei, C.; Wang, H.; Bao, W.; Hui, J.; Berberoglu, M. A.; Sahu, S. K.; Esteban, M.; Ma, K.; Fan, G.; Li, Y.; Liu, S.; Chen, A.; Xu, X.; Dong, Z.; Liu, L.
10.1101/2021.10.21.465298 — developmental biology — Posted on 2021-10-22
1217 Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball patterned arrays
Chen, A.; Liao, S.; Cheng, M.; Ma, K.; Wu, L.; Lai, Y.; Qiu, X.; Yang, J.; Li, W.; Xu, J.; Hao, S.; Wang, X.; Lu, H.; Chen, X.; Liu, X.; Huang, X.; Lin, F.; Li, Z.; Hong, Y.; Fu, D.; Jiang, Y.; Peng, J.; Liu, S.; Shen, M.; Liu, C.; Li, Q.; Yuan, Y.; Zheng, H.; Wang, Z.; Wang, Z.; Huang, X.; Xiang, H.; Han, L.; Qin, B.; Guo, P.; Munoz-Canoves, P.; Thiery, J. P.; Wu, Q.-F.; Zhao, F.; Li, M.; Kuang, H.; Hui, J.; Wang, O.; Lu, H.; Wang, B.; Liu, S.; Ni, M.; Zhang, W.; Mu, F.; Yin, Y.; Yang, H.; Lisby, M.; Cornall, R. J.; Mulder, J.; Uhlen, M.; Esteban, M. A.; Li, Y.; Liu, L.; Xu, X.; Wang, J.
10.1101/2021.01.17.427004 — cell biology — Posted on 2021-10-22
1218 Myosin-X-dependent assembly of the extracellular matrix limits breast cancer invasion
Peuhu, E.; Jacquemet, G.; Scheele, C. L.; Paatero, I.; Thol, K.; Isomursu, A.; Georgiadou, M.; Guzman, C.; Koskinen, S.; Laiho, A.; Elo, L. L.; Boström, P.; Hartiala, P.; van Rheenen, J.; Ivaska, J.
10.1101/2021.10.22.464987 — cell biology — Posted on 2021-10-22
1220 The initiation of the wound healing program is regulated by the convergence of mechanical and epigenetic cues
Bhatt, T.; Hegde, A.; Dey, R.; Ketkar, A.; Pulianmackal, A.; Deb, A.; Rampalli, S.; Jamora, C.
10.1101/2021.10.09.463764 — cell biology — Posted on 2021-10-22
1221 Fishing for survival: importance of shark fisheries for the livelihoods of coastal communities in Western Ghana
Seidu, I.; Brobbey, L. K.; Danquah, E.; Oppong, S. K.; Beuningen, D. v.; Seidu, M.; Dulvy, N. K.
10.1101/2021.01.18.427106 — zoology — Posted on 2021-10-22
1223 Optimized detection of allelic imbalances specific for homologous recombination deficiency improves the prediction of clinical outcomes in cancer
Perez-Villatoro, F.; Oikkonen, J.; Casado, J.; Chernenko, A.; Gulhan, D. C.; Tumiati, M.; Li, Y.; Lavikka, K.; Hietanen, S.; Hynninen, J.; Haltia, U.-M.; Tyrmi, J. S.; Laivuori, H.; Konstantinopoulos, P.; Hautaniemi, S.; Kauppi, L.; Farkkila, A.
10.1101/2021.08.19.456809 — cancer biology — Posted on 2021-10-22
1224 Waves and currents decrease the available space in a salmon cage
Johannesen, A.; Patursson, O.; Kristmundsson, J.; Dam, S. P.; Mulelid, M.; Klebert, P.
10.1101/2021.07.23.453560 — animal behavior and cognition — Posted on 2021-10-22
1225 Aurora B/C-dependent phosphorylation promotesRec8 cleavage in mammalian oocytes
Nikalayevich, E.; El Jailani, S.; Cladiere, D.; Gryaznova, Y.; Fosse, C.; Touati, S. A.; Buffin, E.; Wassmann, K.
10.1101/2021.10.22.465153 — cell biology — Posted on 2021-10-22
1227 Spatially-resolved transcriptomics analyses of invasive fronts in solid tumors
Wu, L.; Yan, J.; Bai, Y.; Chen, F.; Xu, J.; Zou, X.; Huang, A.; Hou, L.; Zhong, Y.; Jing, Z.; Zhou, X.; Sun, H.; Cheng, M.; Ji, Y.; Luo, R.; Li, Q.; Wu, L.; Wang, P.; Guo, D.; Huang, W.; Lei, J.; Liao, S.; Li, Y.; Jiang, Z.; Yao, N.; Yu, Y.; Li, Y.; Liu, F.; Zhang, M.; Yang, H.; Yang, S.; Xu, X.; Liu, L.; Wang, X.; Wang, J.; Fan, J.; Liu, S.; Yang, X.; Chen, A.; Zhou, J.
10.1101/2021.10.21.465135 — cancer biology — Posted on 2021-10-22
1232 Microbial stowaways - waterbirds as dispersal vectors of aquatic pro- and microeukaryotic communities
Szabo, B.; Szabo, A.; Vad, C. F.; Boros, E.; Lukic, D.; Ptacnik, R.; Marton, Z.; Horvath, Z.
10.1101/2021.10.21.465236 — ecology — Posted on 2021-10-22
1234 Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
Czaya, B.; Heitman, K.; Campos, I.; Yanucil, C.; Kentrup, D.; Westbrook, D.; Gutierrez, O.; Babitt, J.; Jung, G.; Salusky, I.; Hanudel, M.; Faul, C.
10.1101/2021.10.22.465390 — cell biology — Posted on 2021-10-22
1235 Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning
Xie, J.; Najafi, J.; Le Borgne, R.; Durieu, C.; Verbavatz, J.-M.; Salle, J.; MINC, N.
10.1101/2021.10.21.465315 — cell biology — Posted on 2021-10-22
1236 Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity
Arputhasamy, C.; Lucanic, M.; Rane, A.; Schmidt, M.; Garett, T.; Foulger, A. C.; Broussalian, M.; Battistoni, E.; Brem, R. B.; Lithgow, G. J.; Chamoli, M.; Andersen, J. K.
10.1101/2021.10.21.465344 — cell biology — Posted on 2021-10-22
1237 Actin filaments act as a size-dependent diffusion barrier around centrosomes
Cheng, H.; Kao, Y.-L.; Sharma, L.; Yang, W.-T.; Huang, S.-H.; Lin, H.-R.; Huang, Y.-S.; Kao, C.-L.; Yang, L.-W.; Bearon, R.; LIN, Y. C.
10.1101/2021.10.21.465377 — cell biology — Posted on 2021-10-22
1240 Unlocking the functional potential of polyploid yeasts
Mozzachiodi, S.; Krogerus, K.; Gibson, B.; Nicolas, A.; Liti, G.
10.1101/2021.10.21.465299 — genetics — Posted on 2021-10-22
1242 Escherichia coli ribosomal protein S1 enhances the kinetics of ribosome biogenesis and RNA decay
Duval, M.; Prevost, K.; Bandyra, K. J.; Helfer, A.-C.; Korepanov, A.; Bakhti, L.; Kuhn, L.; Springer, M.; Romby, P.; Luisi, B. F.; Masse, E.; Marzi, S.
10.1101/2021.10.20.465233 — microbiology — Posted on 2021-10-22
1243 Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts
Barbosa, C.-H. D.; Gomes, A.; Canto, F. B.; Brandao, L. M.; Lima, J. R.; Melo, G. A.; Granato, A.; Neves, E. G.; Oliveira, A.-C.; Dutra, W. O.; Nobrega, A.; Bellio, M.
10.1101/2021.10.21.465260 — immunology — Posted on 2021-10-22
1244 Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy
Masala, N.; Pofahl, M.; Haubrich, A. N.; Sameen Islam, K. U.; Nikbakht, N.; Pasdarnavab, M.; Kamali, F.; Bohmbach, K.; Henneberger, C.; Golcuk, K.; A Ewell, L.; Blaess, S.; Kelly, T.; Beck, H.
10.1101/2020.11.23.393694 — neuroscience — Posted on 2021-10-22
1247 Mitochondrial fission process 1 (MTFP1) controls bioenergetic efficiency and prevents inflammatory cardiomyopathy and heart failure in mice
Donnarumma, E.; Kohlhaas, M.; Vimont, E.; Kornobis, E.; Chaze, T.; Gia Giaetto, Q.; Matondo, M.; Moya-Nilges, M.; Maack, C.; Wai, T.
10.1101/2021.10.21.465262 — physiology — Posted on 2021-10-22
1249 Mining of thousands of prokaryotic genomes reveals high abundance of prophage signals
Lopez-Leal, G.; Camelo-Valera, L. C.; Hurtado-Ramirez, J. M.; Verleyen, J.; Castillo-Ramirez, S.; Reyes-Munoz, A.
10.1101/2021.10.20.465230 — bioinformatics — Posted on 2021-10-22
1251 Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis
Muto, Y.; Dixon, E. E.; Yoshimura, Y.; Wu, H.; Omachi, K.; King, A. J.; Olson, E. N.; Gunawan, M. G.; Kuo, J. J.; Cox, J.; Miner, J. H.; Seliger, S. L.; Woodward, O. M.; Welling, P. A.; Watnick, T. J.; Humphreys, B. D.
10.1101/2021.10.21.465323 — genomics — Posted on 2021-10-22
1252 Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with social behavioral phenotypes
Fabregat, M.; Nino, S.; Pose, S.; Cardenas-Rodriguez, M.; Smolen, C.; Bresque, M.; Hernandez, K.; Prieto-Echagüe, V.; Schlapp, G.; Crispo, M.; Lagos, P.; Lago, N.; Girirajan, S.; Escande, C.; Irigoin, F.; Badano, J. L.
10.1101/2021.10.21.465251 — genetics — Posted on 2021-10-22
1257 Expression of brain-derived neurotrophic factor in basolateral amygdala inputs to lateral septum is necessary for mice to identify socially novel individuals
Rodriguez, L. A.; Kim, S.-H.; Page, S. C.; Nguyen, C. V.; Pattie, E. A.; Hallock, H. L.; Valerino, J.; Maynard, K.; Jaffe, A. E.; Martinowich, K.
10.1101/2021.10.21.464669 — neuroscience — Posted on 2021-10-22
1258 PI4P and BLOC-1 remodel endosomal membranes into tubules
Jani, R. A.; Di Cicco, A.; Keren-Kaplan, T.; Vale-Costa, S.; Hamaoui, D.; Hurbain, I.; Tsai, F.-C.; Dimarco, M.; Mace, A.-S.; Zhu, Y.; Amorim, M. J.; Bassereau, P.; Bonifacino, J. S.; Subtil, A.; Marks, M. S.; Levy, D.; Raposo, G.; Delevoye, C.
10.1101/2021.10.21.465321 — cell biology — Posted on 2021-10-21
1260 Identifying seaweeds species of Chlorophyta, Phaeophyta and Rhodophyta using DNA barcodes
Prasanthi, N.; PrasannaKumar, C.; Annadurai, D.; Mahendran, S.; Alshehri, M. A. H.
10.1101/2020.08.30.274456 — plant biology — Posted on 2021-10-21
1262 Structural basis for long-chain isoprenoids synthesis by cis-prenyltransferases
Giladi, M.; Lisnyansky Bar-El, M.; Vankova, P.; Ferofontov, A.; Melvin, E.; Kavan, D.; Redko, B.; Haimov, E.; Wiener, R.; Man, P.; Haitin, Y.
10.1101/2021.10.21.465316 — biochemistry — Posted on 2021-10-21
1263 A holistic insight of mycobacteriophage induced changes in mycobacterial cells
Calcuttawala, F.; Shaw, R.; Sarbajna, A.; Dutta, M.; Sinha, S.; K. Das Gupta, S.
10.1101/2021.10.21.465286 — molecular biology — Posted on 2021-10-21
1267 Unravelling the role of thyroid hormones in seasonal neuroplasticity in European Starlings (Sturnus vulgaris)
Orije, J. E.; Raymaekers, S. R.; Majumadar, G.; De Groof, G.; Jonckers, E.; Ball, G. F.; Verhoye, M.; Darras, V. M.; Van der Linden, A.
10.1101/2021.10.21.465109 — neuroscience — Posted on 2021-10-21
1268 Temporal pattern recognition in the human brain: a dual simultaneous processing
Bonetti, L.; Brattico, E.; Bruzzone, S. E.; Donati, G.; Deco, G.; Pantazis, D.; Vuust, P.; Kringelbach, M. L.
10.1101/2021.10.21.465263 — neuroscience — Posted on 2021-10-21
1272 Mining transcriptomic data to identify Saccharomyces cerevisiae signatures related to improved and repressed ethanol production under fermentation
Sazegari, S.; Niazi, A.; Zinati, Z.; Eskandari, M. H.; Sima Sazegari,Institute of Biotechnology, Shiraz University, Shiraz, Iran.Ali Niazi, nstitute of Bio,
10.1101/2021.10.21.465282 — bioinformatics — Posted on 2021-10-21
1273 Linking Parasitism to Network Centrality and the Impact of Sampling Bias in its Interpretation
XU, Z.; MacIntosh, A. J. J.; Castellano-Navarro, A.; Macanas-Martuinez, E.; Suzumura, T.; Duboscq, J.
10.1101/2021.06.07.447302 — animal behavior and cognition — Posted on 2021-10-21
1274 Influences of rare copy number variation on human complex traits
Hujoel, M. L. A.; Sherman, M. A.; Barton, A. R.; Mukamel, R. E.; Sankaran, V. G.; Loh, P.-R.
10.1101/2021.10.21.465308 — genetics — Posted on 2021-10-21
1276 Glucocorticoid signaling delays castration-induced regression in murine models of prostate cancer
Maolake, A.; Zhang, R.; Sha, K.; Singh, S.; Pan, C.; Xu, B.; Chatta, G.; Mastri, M.; Eng, K. H.; Nastiuk, K. L.; Krolewski, J. J.
10.1101/2021.10.11.463722 — cancer biology — Posted on 2021-10-21
1277 Equatorial to Polar genomic variability of the microalgae Bathycoccus prasinos
Leconte, J.; Timsit, Y.; Delmont, T. O.; Lescot, M.; Piganeau, G.; Wincker, P.; Jaillon, O.
10.1101/2021.07.13.452163 — genomics — Posted on 2021-10-21
1279 A within-host infection model to explore tolerance andresistance
Pierre, L.; Christine, L.; Parthuisot, N.; Faucher, C.; Duneau, D.; Ferdy, J.-B.
10.1101/2021.10.19.464998 — evolutionary biology — Posted on 2021-10-21
1287 Vision is Required for Cell Type Specification in the Visual Cortex
Cheng, S.; Butrus, S.; Tan, L.; Xu, V.; Sagireddy, S.; Trachtenberg, J.; Shekhar, K.; Zipursky, S. L.
10.1101/2021.08.10.455824 — neuroscience — Posted on 2021-10-21
1289 Comparison of hybrid learning and remote education in the implementation of the 'Adopt a Microorganism' methodology
Rodrigues Cintra Armellini, B.; La Luna, A.; Bueris, V.; Pinto de Almeida, A.; Moraes Tamais, A.; Krzyzanowski Junior, F.; Hasten Reiter, V. S.; Lellis-Santos, C.; Cafe Ferreira, R. d. C.
10.1101/2021.03.09.434548 — scientific communication and education — Posted on 2021-10-21
1290 Arabidopsis PROTODERMAL FACTOR2 binds lysophosphatidylcholines and transcriptionally regulates phospholipid metabolism
Wojciechowska, I.; Mukherjee, T.; Knox-Brown, P.; Hu, X.; Khosla, A.; Mathews, G. L.; Thompson, K. A.; Peery, S. T.; Szlachetko, J.; Thalhammer, A.; Hincha, D. K.; Skirycz, A.; Schrick, K.
10.1101/2021.10.20.465175 — plant biology — Posted on 2021-10-21
1294 The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding.
Rocchi, C.; Louvat, C.; Miele, A. E.; Batisse, J.; Guillon, C.; Ballut, L.; Lener, D.; Negroni, M.; Ruff, M.; Gouet, P.; Fiorini, F.
10.1101/2021.10.21.465253 — biochemistry — Posted on 2021-10-21
1296 Succinate metabolism uncouples retinal pigment epithelium mitochondria
Hass, D. T.; Bisbach, C. M.; Robbings, B. M.; Sadilek, M.; Sweet, I. R.; Hurley, J. B.
10.1101/2021.02.10.430650 — biochemistry — Posted on 2021-10-21
1297 Top2a promotes the development of social behavior via PRC2 and H3K27me3
Geng, Y.; Zhang, T.; Godar, S. C.; Pluimer, B. R.; Harrison, D. L.; Nath, A. K.; Yeh, J.-R. J.; Drummond, I. A.; Bortolato, M.; Peterson, R. T.
10.1101/2021.09.20.461107 — animal behavior and cognition — Posted on 2021-10-21
1298 Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation
Wanigasuriya, I.; Kinkel, S. A.; Beck, T.; Roper, E. A.; Breslin, K.; Lee, H. J.; Keniry, A.; Ritchie, M. E.; Blewitt, M. E.; Gouil, Q.
10.1101/2021.10.21.465360 — genomics — Posted on 2021-10-21
1299 Genetic structure correlates with ethnolinguistic diversity in eastern and southern Africa
Atkinson, E. G.; Dalvie, S.; Pichkar, Y.; Kalungi, A.; Majara, L.; Stevenson, A.; Abebe, T.; Akena, D.; Alemayehu, M.; Ashaba, F. K.; Atwoli, L.; Baker, M.; Chibnik, L. B.; Creanza, N.; Daly, M. J.; Fekadu, A.; Gelaye, B.; Gichuru, S.; Injera, W. E.; James, R.; Kariuki, S. M.; Kigen, G.; Koen, N.; Koenen, K. C.; Koenig, Z.; Kwobah, E.; Kyebuzibwa, J.; Musinguzi, H.; Mwema, R. M.; Neale, B. M.; Newman, C. P.; Newton, C. R. J. C.; Ongeri, L.; Ramachandran, S.; Ramesar, R.; Shiferaw, W.; Stein, D. J.; Stroud, R. E.; Teferra, S.; Zingela, Z.; Martin, A. R.; NeuroGAP-Psychosis Study Team,
10.1101/2021.05.19.444732 — genomics — Posted on 2021-10-21
1303 Commensal bacteria promote type I interferon signaling to maintain immune tolerance
Vasquez Ayala, A.; Matsuo, K.; Hsu, C.-Y.; Carrillo Terrazas, M.; Chu, H.
10.1101/2021.10.21.464743 — immunology — Posted on 2021-10-21
1304 A novel Pan-viral prophylaxis strategy using vaccine adjuvant CAF09b protects against influenza virus infection
Zimmermann, J.; Schmidt, S. T.; Trebbien, R.; Cox, R. J.; Zhou, F.; Follmann, F.; Pedersen, G. K.; Christensen, D.
10.1101/2021.10.21.465243 — immunology — Posted on 2021-10-21
1307 The Mettl3 epitranscriptomic writer amplifies p53 stress responses
Raj, N.; Wang, M.; Seoane, J. A.; Moonie, N. A.; Demeter, J.; Kaiser, A. M.; Boutelle, A. M.; Mulligan, A. S.; Moffatt, C.; Curtis, C.; Chang, H.; Jackson, P. K.; Attardi, L. D.
10.1101/2021.10.21.465324 — cancer biology — Posted on 2021-10-21
1309 The Formation of a Stable Sliding Clamp Discriminates MSH2-MSH3 and MSH2-MSH6 Mismatch Interaction
Britton, B. M.; London, J. A.; Martin-Lopez, J.; Jones, N. D.; Liu, J.; Lee, J.-B.; Fishel, R.
10.1101/2021.10.21.465318 — biochemistry — Posted on 2021-10-21
1311 Multi-omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa
Hearn, J.; Djoko Tagne, C.; Ibrahim, S. S.; Tene-Fossog, B.; Mugenzi, L. J.; Irving, H.; Riveron, J.; Weedall, G. D.; Wondji, C. S.
10.1101/2021.10.21.465247 — genomics — Posted on 2021-10-21
1312 Population genomics of ancient and modern Trichuris trichiura
Doyle, S. R.; Soe, M. J.; Nejsum, P.; Betson, M.; Cooper, P. J.; Peng, L.; Zhu, X.-Q.; Sanchez, A.; Matamoros, G.; Sandoval, G. A. F.; Cutillas, C.; Tchuem Tchuente, L.-A.; Mekonnen, Z.; Ame, S. M.; Namwanje, H.; Levecke, B.; Berriman, M.; Fredensborg, B. L.; Kapel, C. M. O.
10.1101/2021.10.21.464505 — genomics — Posted on 2021-10-21
1313 DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G0 cells
Tyler, J. K.; Fowler, F. C.; Peart, C.; Chen, B.-R.; Sleckman, B.; Zolnerowich, N.; Nussenzweig, A.; Pavani, R.; Wu, W.; Paiano, j.
10.1101/2021.10.21.465258 — molecular biology — Posted on 2021-10-21
1314 Massively parallel identification of zipcodes in primary cortical neurons
von Kuegelgen, N.; Mendonsa, S.; Dantsuji, S.; Ron, M.; Kirchner, M.; Zerna, N.; Bujanic, L.; Mertins, P.; Ulitsky, I.; Chekulaeva, M.
10.1101/2021.10.21.465275 — molecular biology — Posted on 2021-10-21
1315 DOT1L bridges transcription and heterochromatin formation at pericentromeres
Malla, A. B.; Yu, H.; Kadimi, S.; Lam, T.; Cox, A. L.; Smith, Z. D.; Lesch, B. J.
10.1101/2021.10.21.465349 — molecular biology — Posted on 2021-10-21
1316 S100A8 and S100A9, biomarkers of SARS-Cov-2-infected patients, suppress HIV replication in primary macrophages
Oguariri, R. M.; Brann, T. W.; Adelsberger, J. W.; Chen, Q.; Goswami, S.; Mele, A. R.; Imamichi, T.
10.1101/2021.10.20.464686 — microbiology — Posted on 2021-10-21
1318 A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes
Borgo, G. M.; Burke, T. P.; Tran, C. J.; Lo, N. T. N.; Engström, P.; Welch, M. D.
10.1101/2021.10.21.465009 — microbiology — Posted on 2021-10-21
1319 SOCS3-mediated activation of p53-p21-NRF2 axis and cellular adaptation to oxidative stress in SOCS1-deficient hepatocellular carcinoma
Khan, M. M.; Boufaied, N.; Yeganeh, M.; Ghosh, A.; Kandhi, R.; Bagheri, R.; Petkiewicz, S.; Sharma, A.; Yoshimura, A.; Ferbeyre, G.; Labbe, D. P.; Ramanathan, S.; Ilangumaran, S.
10.1101/2021.10.21.465149 — cancer biology — Posted on 2021-10-21
1322 Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase
Ji, Z.; Li, H.; Peterle, D.; Paulo, J. A.; Ficarro, S. B.; Wales, T. E.; Marto, J.; Gygi, S.; Engen, J. R.; Rapoport, T. A.
10.1101/2021.10.21.465358 — biochemistry — Posted on 2021-10-21
1325 Plasticity of Neural Connections Underlying Oxytocin-mediated Parental Behaviors of Male Mice
Inada, K.; Hagihara, M.; Tsujimoto, K.; Abe, T.; Konno, A.; Hirai, H.; Kiyonari, H.; Miyamichi, K.
10.1101/2021.10.20.465207 — neuroscience — Posted on 2021-10-21
1327 PyDesigner: A Pythonic Implementation of the DESIGNER Pipeline for Diffusion Tensor and Diffusional Kurtosis Imaging
Dhiman, S.; Teves, J. B.; Thorn, K. E.; McKinnon, E. T.; Moss, H. G.; Adisetiyo, V.; Ades-Aron, B.; Veraart, J.; Chen, J.; Fieremans, E.; Benitez, A.; Helpern, J. A.; Jensen, J. H.
10.1101/2021.10.20.465189 — neuroscience — Posted on 2021-10-21
1328 Single-cell Stereo-seq enables cell type-specific spatial transcriptome characterization in Arabidopsis leaves
Xia, K.; Sun, H.-X.; Li, J.; Li, J.; Zhao, Y.; Chen, R.; Liu, G.; Chen, Z.; Yin, R.; Hao, S.; Wang, J.; Xie, Q.; Xu, J.; Li, Y.; Chen, A.; Liu, L.; Yin, Y.; Yang, H.; Wang, J.; Gu, Y.; Xu, X.
10.1101/2021.10.20.465066 — plant biology — Posted on 2021-10-21
1330 Markerless mouse tracking for social experiments
Le, V. A.; Sterley, T.-L.; Cheng, N.; Bains, J.; Murari, K.
10.1101/2021.10.20.464614 — bioengineering — Posted on 2021-10-21
1331 Severe fever with thrombocytopenia syndrome virus and parthenogenetic Asian longhorned tick Haemaphysalis longicornis (Acari: Ixodidae)
Zheng, A.; Zhang, Z.; Zhang, G.; Zhan, X. Z.; Zhang, X.; Zhao, C.; Cheng, C.; Li, H.; Yu, T.; Lawrence, K. L.; Sun, J.; Yang, Z.; Ye, L.; Chu, H. C.; Wang, Y. W.; Han, X.; Jia, Y.; Fan, S.; Kanuka, H.; Tanaka, T.; Jenkins, C.; Gedye, K.; Chandra, S.; Price, D. C.; Liu, Q.; Choi, Y. K.
10.1101/2021.10.20.465214 — evolutionary biology — Posted on 2021-10-21
1332 Microplastic pollution of commercial fishes from coastal and offshore waters, Japan
Yagi, M.; Kobayashi, T.; Maruyama, Y.; Hoshina, S.; Masumi, S.; Aizawa, I.; Uchida, J.; Kinoshita, T.; Yamawaki, N.; Aoshima, T.; Morii, Y.; Shimizu, K.
10.1101/2021.10.20.465208 — ecology — Posted on 2021-10-21
1334 Diamond Raman Laser and Yb Fiber Amplifier for In Vivo Multiphoton Fluorescence Microscopy
Engelmann, S. A.; Zhou, A.; Hassan, A. M.; Williamson, M. R.; Jarrett, J. W.; Perillo, E. P.; Spence, D. J.; Jones, T. A.; Dunn, A. K.
10.1101/2021.10.20.464141 — neuroscience — Posted on 2021-10-21
1336 Endoplasmic Reticulum Chaperone Genes Encode Effectors of Long-Term Memory
Chatterjee, S.; Bahl, E.; Mukherjee, U.; Walsh, E. N.; Shetty, M. S.; Yan, A. L.; Vanrobaeys, Y.; Lederman, J. D.; Giese, K. P.; Michaelson, J.; Abel, T.
10.1101/2021.10.20.465191 — neuroscience — Posted on 2021-10-21
1337 The Carotid Body Detects Circulating Tumor Necrosis Factor-Alpha to Activate a Sympathetic Anti-Inflammatory Reflex
Katayama, P. L.; Leirao, I. d. P.; Kanashiro, A.; Luiz, J. P. M.; Cunha, F. Q.; Navegantes, L. C. C.; Menani, J. V.; Zoccal, D. B.; Colombari, D. S. d. A.; Colombari, E.
10.1101/2021.10.20.463417 — neuroscience — Posted on 2021-10-21
1341 Arabidopsis PROTODERMAL FACTOR2 binds lysophosphatidylcholines and transcriptionally regulates phospholipid metabolism
Wojciechowska, I.; Mukherjee, T.; Knox-Brown, P.; Hu, X.; Khosla, A.; Mathews, G. L.; Thompson, K. A.; Peery, S. T.; Szlachetko, J.; Thalhammer, A.; Hincha, D. K.; Skirycz, A.; Schrick, K.
10.1101/2021.10.20.465175 — plant biology — Posted on 2021-10-21
1343 3D-mapping of human lymph node and spleen reveals integrated neuronal, vascular, and ductal cell networks
Currlin, S.; Nick, H.; Nick, J.; Brusko, M.; Hakimian, H.; Penaloza-Aponte, J.; Rodriguez, N.; Medina-Serpas, M.; Yang, M.; Kusmartseva, I.; Brusko, T.; Otto, K.; Posgai, A.; Wasserfall, C.; Atkinson, M. A.
10.1101/2021.10.20.465151 — immunology — Posted on 2021-10-21
1345 A transcriptional constraint mechanism limits the homeostatic response to activity deprivation in mammalian neocortex
Valakh, V.; Zhu, X. A.; Wise, D. L.; Van Hooser, S.; Schectman, R.; Cepeda, I.; Kirk, R.; O'Toole, S. M.; Nelson, S. B.
10.1101/2021.10.20.465163 — neuroscience — Posted on 2021-10-21
1348 NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer
Doffo, J.; Bamopoulos, S. A.; Kose, H.; Orben, F.; Pons, M.; den Dekker, A. T.; Brouwer, R. W. W.; Baluapuri, A.; Habringer, S.; Reichert, M.; Illendula, A.; Kramer, O. H.; Schick, M.; Wolf, E.; van IJcken, W. F. J.; Esposito, I.; Keller, U.; Schneider, G.; Wirth, M.
10.1101/2021.10.21.465266 — cancer biology — Posted on 2021-10-21
1352 Sponge contribution to the silicon cycle of a diatom-rich shallow bay
Lopez-Acosta, M.; Maldonado, M.; Grall, J.; Ehrhold, A.; Sitja, C.; Galobart, C.; Leynaert, A.
10.1101/2021.10.20.465147 — ecology — Posted on 2021-10-21
1353 A multimodal imaging and analysis pipeline for creating a cellular census of the human cerebral cortex
Costantini, I.; Morgan, L.; Yang, J.; Balbastre, Y.; Varadarajan, D.; Pesce, L.; Scardigli, M.; Mazzamuto, G.; Gavryusev, V.; Castelli, F. M.; Roffilli, M.; Silvestri, L.; Laffey, J.; Raia, S.; Varghese, M.; Wicinski, B.; Chang, S.; Chen I-Chun, A.; Wang, H.; Cordero, D.; Vera, M.; Nolan, J.; Nestor, K.; Mora, J.; Iglesias, J. E.; Pallares, E. G.; Evancic, K.; Augustinack, J.; Fogarty, M.; Dalca, A. V.; Frosch, M.; Magnain, C.; Frost, R.; van der Kouwe, A.; Chen, S.-C.; Boas, D. A.; Pavone, F. S.; Fischl, B.; Hof, P. R.
10.1101/2021.10.20.464979 — neuroscience — Posted on 2021-10-21
1355 Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage
Praznik, A.; Fink, T.; Franko, N.; Lonzaric, J.; Bencina, M.; Jerala, N.; Plaper, T.; Roskar, S.; Jerala, R.
10.1101/2021.10.19.464966 — synthetic biology — Posted on 2021-10-21
1356 Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities
Yousefi, M.; Boross, G.; Weiss, C.; Murray, C. W.; Hebert, J. D.; Cai, H.; Ashkin, E. L.; Karmakar, S.; Andrejka, L.; Chen, L.; Wang, M.; Tsai, M. K.; Lin, W.-Y.; Li, C.; Yakhchalian, P.; Colon, C. I.; Chew, S.-K.; Chu, P.; Swanton, C.; Kunder, C. A.; Petrov, D. A.; Winslow, M. M.
10.1101/2021.10.20.464849 — cancer biology — Posted on 2021-10-21
1357 Spatial transcriptomics reveals the two cancer stem cell-like populations in triple-negative breast cancer
Nakayama, J.; Matsunaga, H.; Arikawa, K.; Yoda, T.; Hosokawa, M.; Takeyama, H.; Yamamoto, Y.; Semba, K.
10.1101/2021.10.21.465257 — cancer biology — Posted on 2021-10-21
1358 Pre-neoplastic stromal cells drive BRCA1-mediated breast tumorigenesis
Nee, K.; Ma, D.; Nguyen, Q. H.; Pervolarakis, N.; Insua-Rodriguez, J.; Pein, M.; Gong, Y.; Hernandez, G.; Alshetaiwi, H.; Williams, J.; Rauf, M.; Dave, K. R.; Boyapati, K.; Calderon, C.; Markaryan, A.; Edwards, R.; Lin, E.; Parajuli, R.; Zhou, P.; Nie, Q.; Shalabi, S.; LaBarge, M. A.; Kessenbrock, K.
10.1101/2021.10.20.465221 — cancer biology — Posted on 2021-10-21
1359 REViewer: Haplotype-resolved visualization of read alignments in and around tandem repeats
Dolzhenko, E.; Weisburd, B.; Ibanez, K.; Rajan Babu, I. S.; Bennett, M. F.; Billingsley, K. J.; Carroll, A.; Danzi, M. C.; Deshpande, V.; Ding, J.; Fazal, S.; Halman, A.; Jadhav, B.; Qiu, Y.; Richmond, P.; Scheffler, K.; van Vugt, J. J. F. A.; Zwamborn, R. R. A. J.; Genomics England Research Consortium, ; Chong, S. S.; Friedman, J. M.; Tucci, A.; Rehm, H. L.; Eberle, M. A.
10.1101/2021.10.20.465046 — bioinformatics — Posted on 2021-10-21
1363 Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
Robinson, P. S.; Thomas, L. E.; Abascal, F.; Jung, H.; Harvey, L.; West, H. D.; Olafsson, S.; Lee, B. C. H.; Coorens, T.; Lee-Six, H.; Butlin, L.; Lander, N.; Sanders, M. A.; Lensing, S.; Buczacki, S. J. A.; ten Hoppen, R.; Coleman, N.; Brunton-Sim, R.; Rushbrook, S.; Saeb-Parsy, K.; Lalloo, F.; Campbell, P. J.; Martincorena, I.; Sampson, J. R.; Stratton, M. R.
10.1101/2021.10.20.465093 — genomics — Posted on 2021-10-21
1364 Dual domestication, diversity, and differential introgression in Old World cotton diploids
Grover, C. E.; Arick, M. A.; Thrash, A.; Sharbrough, J.; Hu, G.; Yuan, D.; Miller, E. R.; Ramaraj, T.; Peterson, D. G.; Udall, J. A.; Wendel, J. F.
10.1101/2021.10.20.465142 — evolutionary biology — Posted on 2021-10-21
1365 Plant organic matter inputs exert a strong control on soil organic matter decomposition in a thawing permafrost peatland
Wilson, R. M.; Hough, M.; Verbeke, B.; Hodgkins, S.; Isogenie Coordinators, ; Chanton, J.; Saleska, S.; Rich, V.; Tfaily, M.
10.1101/2021.10.20.465126 — ecology — Posted on 2021-10-21
1366 Soil viral communities are structured by pH at local and global scales
Lee, S.; Sorensen, J. W.; Walker, R. L.; Emerson, J. B.; Nicol, G. W.; Hazard, C.
10.1101/2021.10.20.465127 — ecology — Posted on 2021-10-21
1368 Systematic identification of yeast mutants with increased rates of cell death reveals rapid stochastic necrosis associated with cell division
Alexandrov, A. I.; Grosfeld, E. V.; Mitkevich, O. V.; Bidiuk, V. A.; Nostaeva, A. V.; Kukhtevich, I. V.; Schneider, R.; Shilov, E. S.; Kushnirov, V. V.; Dmitriev, S. E.; Gladyshev, V. N.
10.1101/2021.10.20.465133 — cell biology — Posted on 2021-10-21
1369 Persistent synaptic inhibition of the subthalamic nucleus by high frequency stimulation
Steiner, L. A.; Kuehn, A. A.; Geiger, J. R.; Alle, H.; Popovic, M.; Kalia, S.; Hodaie, M.; Lozano, A.; Hutchison, W. D.; Milosevic, L.
10.1101/2021.10.20.465131 — neuroscience — Posted on 2021-10-21
1371 Spatiotemporal solidification of α-synuclein inside the liquid droplets
Ray, S.; Chatterjee, D.; Mukherjee, S.; Patel, K.; Mahato, J. K.; Kadam, S.; Krishnan, R.; Sawner, A. S.; Poudyal, M.; Krishnamoorthy, G.; Chowdhury, A.; Padinhateeri, R.; Maji, S. K.
10.1101/2021.10.20.465113 — biophysics — Posted on 2021-10-21
1372 Cryo-EM structures of pentameric autoinducer-2 exporter from E. coli reveal its transport mechanism
Khera, R.; Mehdipour, A. R.; Bolla, J. R.; Kahnt, J.; Welsch, S.; Ermler, U.; Muenke, C.; Robinson, C. V.; Hummer, G.; Xie, H.; Michel, H.
10.1101/2021.10.20.465058 — biophysics — Posted on 2021-10-21
1373 Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex
MISSEY, F.; BOTZANOWSKI, B.; MIGLIACCIO, L.; ACERBO, E.; GLOWACKI, E. D.; WILLIAMSON, A.
10.1101/2021.10.20.465090 — bioengineering — Posted on 2021-10-21
1374 Evidence for a conserved queen-worker genetic toolkit across slave-making ants and their ant hosts
Feldmeyer, B.; Gstoettl, C.; Wallner, J.; Jongepier, E.; Seguret, A.; Grasso, A.; Bornberg-Bauer, E.; Foitzik, S.; Heinze, J.
10.1101/2021.10.20.465091 — evolutionary biology — Posted on 2021-10-21
1375 Coral settlement and recruitment responses to reef fish foraging and trait diversity
Chow, C. F. Y.; Bolton, C.; Boutros, N.; Brambilla, V.; Fontoura, L.; Hoey, A. S.; Madin, J. S.; Pizarro, O.; Torres-Pulliza, D.; Woods, R. M.; Zawada, K. J. A.; Barbosa, M.; Dornelas, M.
10.1101/2021.10.19.464984 — ecology — Posted on 2021-10-21
1376 Arnold tongue entrainment reveals dynamicalprinciples of the embryonic segmentation clock
Sanchez, P. G. L.; Mochulska, V.; Mauffette Denis, C.; Moenke, G.; Tomita, T.; Tsuchida-Straeten, N.; Petersen, Y.; Sonnen, I.; Francois, P.; Aulehla, A.
10.1101/2021.10.20.465101 — developmental biology — Posted on 2021-10-21
1383 Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors
Campanacci, V.; Urvoas, A.; Ammar Khodja, L.; Aumont-Nicaise, M.; Noiray, M.; Lachkar, S.; Curmi, P. A.; Minard, P.; Gigant, B.
10.1101/2021.10.19.464980 — biochemistry — Posted on 2021-10-21
1384 Natural variation further increases resilience of sorghum bred for chronically drought-prone environments
Dong, H.; Birhan, T.; Abajebel, N.; Wakjira, M.; Mitiku, T.; Lemke, C.; Vadez, V.; Paterson, A. H.; Bantte, K.
10.1101/2021.10.20.465110 — genetics — Posted on 2021-10-21
1386 Geometric effects of volume to surface mapping of fMRI data
Ciantar, K. G.; Farrugia, C.; Scerri, K.; Xu, T.; Bajada, C. J.
10.1101/2020.11.09.373860 — neuroscience — Posted on 2021-10-21
1388 Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward
Engeln, M.; Fox, M. E.; Chandra, R.; Choi, E. Y.; Nam, H.; Qadir, H.; Thomas, S. S.; Rhodes, V. M.; Turner, M. D.; Herman, R. J.; Calarco, C. A.; Lobo, M. K.
10.1101/2021.10.20.465105 — neuroscience — Posted on 2021-10-21
1389 Signatures of Brain Network Alteration in Psychogenic Non-Epileptic Seizures: A Rest-EEG Study Based on Power Spectral Density and Phase Lag Index
Varone, G.; Boulila, W.; Lo Giudice, M.; Benjdira, B.; Mammone, N.; Ieracitano, C.; Dashtipour, K.; Neri, S.; Gasparini, S.; Morabito, F. C.; Hussain, A.; Aguglia, U.
10.1101/2021.10.20.464353 — neuroscience — Posted on 2021-10-21
1390 Protein sequence profile prediction using ProtAlbert transformer
Zare-Mirakabad, F.; Behjati, A.; Arab, S. S.; Nowzari-Dalini, A.
10.1101/2021.09.23.461475 — bioinformatics — Posted on 2021-10-21
1391 2020 BioImage Analysis Survey: Community experiences and needs for the future
Jamali, N.; Dobson, E. T.; Eliceiri, K. W.; Carpenter, A. E.; Cimini, B. A.
10.1101/2021.08.16.456498 — bioinformatics — Posted on 2021-10-21
1393 Distributed brain co-processor for tracking electrophysiology and behavior during electrical brain stimulation
Sladky, V.; Nejedly, P.; Mivalt, F.; Brinkmann, B. H.; Kim, I.; St. Louis, E. K.; Gregg, N. M.; Lundstrom, B. N.; Crowe, C. M.; Pal Attia, T.; Crepeau, D.; Balzekas, I.; Marks, V.; Wheeler, L. P.; Cimbalnik, J.; Cook, M.; Janca, R.; Sturges, B. K.; Leyde, K.; Miller, K. J.; Van Gompel, J. J.; Denison, T.; Worrell, G. A.; Kremen, V.
10.1101/2021.03.08.434476 — bioengineering — Posted on 2021-10-21
1395 Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing's syndrome
Omar, M. H.; Byrne, D. P.; Jones, K. N.; Lakey, T. M.; Collins, K. B.; Lee, K.-S.; Daly, L. A.; Forbush, K. A.; Lau, H.-T.; Golkowski, M.; McKnight, G. S.; Breault, D. T.; Lefrancois-Martinez, A.-M.; Martinez, A.; Eyers, C. E.; Baird, G. S.; Ong, S.-E.; Smith, F. D.; Eyers, P. A.; Scott, J. D.
10.1101/2021.10.18.464848 — molecular biology — Posted on 2021-10-21
1397 Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response
Zaini, A.; Dalit, L.; Sheikh, A. A.; Thiele, D.; Zhang, Y.; Runting, J.; Rodrigues, G.; Ng, J.; Bramhall, M.; Scheer, S.; Hailes, L.; Groom, J. R.; Good-Jacobson, K. L.; Zaph, C.
10.1101/2021.10.20.465079 — immunology — Posted on 2021-10-21
1399 Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
Thirmanne, H. N.; Wu, F.; Janssens, D. H.; Swanger, J.; Feldman, H.; Amezquita, R.; Gottardo, R.; Paddison, P. J.; Henikoff, S.; Clurman, B. E.
10.1101/2021.10.19.464955 — cancer biology — Posted on 2021-10-21
1401 CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Schatton, D.; Di Pietro, G.; Szczepanowska, K.; Veronese, M.; Marx, M.-C.; Braunohler, K.; Barth, E.; Muller, S.; Giavalisco, P.; Langer, T.; Trifunovic, A.; Rugarli, E. I.
10.1101/2021.10.20.465082 — cell biology — Posted on 2021-10-21
1403 Immortalization and Functional Screening of Natively Paired Human T Cell Receptor Repertoires
Fahad, A. S.; Yu Chung, C.; Lopez Acevedo, S. N.; Boyle, N.; Madan, B.; Gutierrez-Gonzalez, M. F.; Matus-Nicodemos, R.; Laflin, A. D.; Ladi, R. R.; Zhou, J.; Wolfe, J.; Llewellyn-Lacey, S.; Doueck, D.; Balfour, H. H.; Price, D. A.; DeKosky, B. J.
10.1101/2021.10.19.465057 — immunology — Posted on 2021-10-21
1409 Cooperative Allostery and Structural Dynamics of Streptavidin at Cryogenic- and Ambient-temperature
Ayan, E.; Yuksel, B.; Destan, E.; Ertem, F. B.; Yildirim, G.; Eren, M.; Yefanov, O. M.; Barty, A.; Tolstikova, A.; Ketawala, G. K.; Botha, S.; Dao, E. H.; Hayes, B.; Liang, M.; Seaberg, M. H.; Hunter, M. S.; Batyuk, A.; Mariani, V.; Su, Z.; Poitevin, F.; Yoon, C. H.; Kupitz, C.; Cohen, A.; Doukov, T.; Sierra, R. G.; Dag, C.; DeMirci, H.
10.1101/2021.09.23.461567 — biophysics — Posted on 2021-10-21
1411 Reference genomes of 545 silkworms enable high-throughput exploring genotype-phenotype relationships
Tong, X.; Han, M.-j.; Lu, K.; Tai, S.; Liang, S.; Liu, Y.; Hu, H.; Shen, J.; Long, A.; Zhan, C.; Ding, X.; Gao, Q.; Zhang, B.; Tan, D.; Yuan, Y.; Guo, N.; Li, Y.; Wu, Z.; Liu, L.; Li, C.; Lu, Y.; Gai, T.; Zhang, Y.; Yang, R.; Qian, H.; Liu, Y.; Luo, J.; Zheng, L.; Lou, J.; Peng, Y.; Zuo, W.; Song, J.; He, S.; Wu, S.; Zou, Y.; Zhou, L.; Zhou, L.; Cheng, L.; Tang, Y.; Cheng, G.; Yuan, L.; He, W.; Xu, J.; Fu, T.; Xiao, Y.; Lei, T.; Xu, A.; Yin, Y.; Wang, J.; Monteiro, A.; Westhof, E.; Lu, C.; Tian, Z.; Wang, W.; Xiang, Z.; Dai, F.
10.1101/2021.09.28.462073 — genomics — Posted on 2021-10-21
1412 Genetic and genomic architecture of species-specific cuticular hydrocarbon variation in parasitoid wasps
Buellesbach, J.; Holze, H.; Schrader, L.; Liebig, J.; Schmitt, T.; Gadau, J.; Niehuis, O.
10.1101/2021.10.18.464893 — genetics — Posted on 2021-10-21
1413 Direct differentiation of Dental Pulp Pluripotent-like Stem Cells differentiation into Hepatocyte-like Cells
Gil-Recio, C.; Montori, S.; Vallejo, C.; Al Demour, S.; Ferres-Padro, E.; Barajas, M.; Martin, C.; Al Madhoun, A.; Atari, M.
10.1101/2020.12.09.418780 — cell biology — Posted on 2021-10-21
1414 Regulatory variants active in iPSC-derived pancreatic progenitor cells are associated with Type 2 Diabetes in adults
Nguyen, J. P.; iPSCORE Consortium, ; D'Antonio-Chronowska, A.; Fujita, K.; Salgado, B. M.; Matsui, H.; Arthur, T. D.; Donovan, M. K.; D'Antonio, M.; Frazer, K. A.
10.1101/2021.10.20.465206 — genetics — Posted on 2021-10-21
1416 MS2 RNA aptamer enhances prime editing in rice
Chai, Y.; Jiang, Y.; Wang, J.; Qiao, D.; Zhang, Y.; Xin, C.; Zhou, Y.; Wang, X.-C.; Chen, Q.-J.
10.1101/2021.10.20.465209 — molecular biology — Posted on 2021-10-21
1418 Long-range regulatory effects of Neandertal DNA in modern humans
Yermakovich, D.; Pankratov, V.; Vosa, U.; Estonian Biobank Research Team, ; Yunusbayev, B.; Dannemann, M.
10.1101/2021.10.20.464628 — genomics — Posted on 2021-10-21
1423 Direct observation of adaptive tracking on ecological timescales in Drosophila
Rudman, S. M.; Greenblum, S. I.; Rajpurohit, S.; Betancourt, N. J.; Hanna, J.; Tilk, S.; Yokoyama, T.; Petrov, D. A.; Schmidt, P.
10.1101/2021.04.27.441526 — evolutionary biology — Posted on 2021-10-20
1425 Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts
Schiff, L.; Migliori, B.; Chen, Y.; Carter, D.; Bonilla, C.; Hall, J.; Fan, M.; Tam, E.; Ahadi, S.; Fischbacher, B.; Geraschenko, A.; Hunter, C. J.; Venugopalan, S.; DesMarteau, S.; Narayanaswamy, A.; Jacob, S.; Armstrong, Z.; Ferrarotto, P.; Williams, B.; Buckley-Herd, G.; Hazard, J.; Goldberg, J.; Coram, M.; Otto, R.; Baltz, E. A.; Andres-Martin, L.; Pritchard, O.; Duren-Lubanski, A.; Daigavane, A.; Reggio, K.; NYSCF Global Stem Cell Array Team, ; Bauer, L.; Aiyar, R. S.; Schwarzbach, E.; Paull, D.; Noggle, S. A.; Monsma, F. J.; Berndl, M.; Yang, S. J.; Johannesson, B.
10.1101/2020.11.13.380576 — cell biology — Posted on 2021-10-20
1429 Locational memory of macrovessel vascular cells is transcriptionally imprinted
Spanjersberg, T. C. F.; Oosterhoff, L. A.; Kruitwagen, H. S.; van den Dungen, N. A. M.; Harakalova, M.; Mokry, M.; Spee, B.; van Steenbeek, F. G.
10.1101/2021.10.20.465092 — cell biology — Posted on 2021-10-20
1431 Dlk1-Dio3 cluster miRNAs regulate mitochondrial functions in Duchenne muscular dystrophy
VU Hong, A.; Bourg, N.; Sanatine, P.; Poupiot, J.; Charton, K.; Gicquel, E.; Massourides, E.; Spinazzi, M.; Richard, I.; Israeli, D.
10.1101/2021.10.20.464950 — physiology — Posted on 2021-10-20
1433 leADS: improved metabolic pathway inference based on active dataset subsampling
Abul-Basher, A.; Nallan, A. N.; McLaughlin, R. J.; Anstett, J.; Hallam, S. J.
10.1101/2020.09.14.297424 — bioinformatics — Posted on 2021-10-20
1434 Protein sequence profile prediction using ProtAlbert transformer1
Zare-Mirakabad, F.; Behjati, A.; Arab, S. S.; Nowzari-Dalini, A.
10.1101/2021.09.23.461475 — bioinformatics — Posted on 2021-10-20
1435 Gigapixel behavioral and neural activity imaging with a novel multi-camera array microscope
Thomson, E.; Harfouche, M.; Konda, P.; Seitz, C. W.; Kim, K.; Cooke, C.; Xu, S.; Blazing, R.; Chen, Y.; Jacobs, W. S.; Park, J.; Dunn, T. W.; Sharma, S.; Horstmeyer, R. W.; Naumann, E. A.
10.1101/2021.10.05.461695 — bioengineering — Posted on 2021-10-20
1436 Harnessing genetic diversity in the USDA pea (Pisum sativum L.) germplasm collection through genomic prediction
Bari, M. A. A.; Zheng, P.; Viera, I.; Worral, H.; Szwiec, S.; Ma, Y.; Main, D.; Coyne, C. J.; McGee, R.; Bandillo, N.
10.1101/2021.05.07.443173 — genomics — Posted on 2021-10-20
1437 When are bacteria really gazelles? Comparing patchy ecologies with dimensionless numbers
Urmy, S. S.; Cramer, A. N.; Rogers, T. L.; Sullivan-Stack, J.; Schmidt, M. L.; Stewart, S. D.; Symons, C. C.
10.1101/2021.10.15.464607 — ecology — Posted on 2021-10-20
1442 A Tissue-Bioengineering Strategy for Modeling Rare Human Kidney Diseases In Vivo
Hernandez, J.; Wang, X.; Vazquez-Segoviano, M.; Sobral-Reyes, M. F.; Moran-Horowich, A.; Sundberg, M.; Lopez-Marfil, M.; Lopez-Cantu, D. O.; Probst, C.; Ruiz-Esparza, G.; Giannikou, K.; Henske, E.; Kwiatkowski, D.; Sahin, M.; Lemos, D. R.
10.1101/2021.10.20.465120 — bioengineering — Posted on 2021-10-20
1443 CandyCollect: At-home saliva sampling for respiratory pathogen capture
Lee, U. N.; Su, X.; Hieber, D. L.; Tu, W.-c.; McManamen, A. M.; Takezawa, M. G.; Hassan, G. W.; Chan, T. C.; Adams, K. N.; Wald, E. R.; DeMuri, G. P.; Berthier, E.; Theberge, A. B.; Thongpang, S.
10.1101/2021.10.19.464911 — bioengineering — Posted on 2021-10-20
1445 Dynamic chromosomal interactions and control of heterochromatin positioning by Ki67
van Schaik, T.; Manzo, S. G.; Vouzas, A. E.; Gilbert, D. M.; van Steensel, B.
10.1101/2021.10.20.465140 — genomics — Posted on 2021-10-20
1446 Genome-wide distribution of Rad26 and Rad1-Rad10 reveals their relationship with Mediator and RNA polymerase II
Gopaul, D.; Wilkes, C. D.; Goldar, A.; Aiach, N. G.; Barrault, M.-B.; Novikova, E.; Soutourina, J.
10.1101/2021.10.20.465181 — genomics — Posted on 2021-10-20
1447 The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction
Coutelier, H.; Ilioaia, O.; Le Peillet, J.; Hamon, M.; D'Amours, D.; Teixeira, M. T.; Xu, Z.
10.1101/2021.10.20.465143 — genetics — Posted on 2021-10-20
1450 Cholesterol biosynthetic pathway induces cellular senescence through ERRa
Ziegler, D. V.; Vernier, M.; Czarnecka-Herok, J.; Scholtes, C.; Machon, C.; Guitton, J.; Rieusset, J.; Giguere, V.; Martin, N.; Bernard, D.
10.1101/2021.10.20.465100 — cell biology — Posted on 2021-10-20
1451 C/EBPα acts as an RNA binding protein essential for its chromatin recruitment and promotes Macrophage differentiation
Zhang, Y.; Bassal, M.; Friedrich, D.; Ummarino, S.; Verbiest, T.; Zhang, J.; Tenen, D.; Haribabu, A.; Tenen, D. G.
10.1101/2021.10.20.465166 — cell biology — Posted on 2021-10-20
1452 Limited specificity of molecular interactions incurs an environment-dependent fitness cost in bacteria
Igler, C.; Fourcade, C.; Waldminghaus, T.; Pauler, F.; Santhanam, B.; Tkacik, G.; Guet, C. C.
10.1101/2021.10.20.465141 — molecular biology — Posted on 2021-10-20
1455 Human milk oligosaccharides reduce murine group B Streptococcus vaginal colonization with minimal impact on the vaginal microbiota
Mejia, M. E.; Ottinger, S.; Vrbanac, A.; Babu, P.; Zulk, J.; Moorshead, D.; Bode, L.; Nizet, V.; Patras, K.
10.1101/2021.10.20.465155 — microbiology — Posted on 2021-10-20
1457 A novel innate pathogen sensing strategy involving ubiquitination of bacterial surface proteins
Apte, S.; Bhutda, S.; Ghosh, S.; Sharma, K.; Sahay, O.; Rakshit, J.; Sinha, A. R.; Dibyachintan, S.; Roy, S.; Datey, A.; Santra, S.; Joseph, J.; Sasidharan, S.; Hammerschmidt, S.; Chakravortty, D.; Santra, M.; Banerjee, A.
10.1101/2021.10.20.465158 — microbiology — Posted on 2021-10-20
1460 Structural Basis for the Inhibition of IAPP Fibril Formation by the Hsp60 Co-Chaperonin Prefoldin
Toerner, R.; Kupreichyk, T.; Gremer, L.; Colas Debled, E.; Fenel, D.; Gans, P.; Willbold, D.; Schoehn, G.; Hoyer, W.; Boisbouvier, J.
10.1101/2021.10.20.465084 — biophysics — Posted on 2021-10-20
1461 MKLP2 functions in early mitosis to ensure proper chromosome congression
Schrock, M. S.; Scarberry, L.; Stromberg, B. R.; Sears, C.; Torres, A. E.; Tallman, D.; Krupinski, L.; Chakravarti, A.; Summers, M. K.
10.1101/2021.09.12.459884 — cell biology — Posted on 2021-10-20
1462 High-throughput identification of RNA localization elements reveals a regulatory role for A/G rich sequences
Arora, A.; Gutierrez, R. C.; Eletto, D.; Becker, R.; Brown, M.; Moor, A. E.; Russ, H. A.; Taliaferro, M.
10.1101/2021.10.20.465152 — molecular biology — Posted on 2021-10-20
1467 Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line
Niemeyer, D.; Schroeder, S.; Friedmann, K.; Weege, F.; Trimpert, J.; Richter, A.; Stenzel, S.; Jansen, J.; Emanuel, J.; Kazmierski, J.; Pott, F.; Jeworowski, L. M.; Olmer, R.; Jaboreck, M.-C.; Tenner, B.; Papies, J.; Heinze, J.; Walper, F.; Schmidt, M. L.; Heinemann, N.; Moencke-Buchner, E.; Veith, T.; Baumgardt, M.; Hoffmann, K.; Widera, M.; Thao, T. T. N.; Balazs, A.; Schulze, J.; Mache, C.; Morkel, M.; Ciesek, S.; Hanitsch, L. G.; Mall, M.; Hocke, A. C.; Thiel, V.; Osterrieder, K.; Wolff, T.; Martin, U.; Corman, V. M.; Mueller, M. A.; Goffinet, C.; Drosten, C.
10.1101/2021.10.20.465121 — microbiology — Posted on 2021-10-20
1468 An intranasally administrated SARS-CoV-2 beta variant subunit booster vaccine prevents beta variant viral replication in rhesus macaques
Sui, Y.; Li, J.; Andersen, H.; Zhang, R.; Prabhu, S.; Hoang, T.; Venzon, D.; Cook, A.; Brown, R.; Teow, E.; Velasco, J.; Pessaint, L.; Moore, I.; lagenaur, L.; Talton, J.; Kramer, J.; Breed, M.; Bock, K.; Minai, M.; Nagata, B.; Choo-Wosoba, H.; Lewis, M.; Wang, L.-X.; Berzofsky, J.
10.1101/2021.10.19.464990 — immunology — Posted on 2021-10-20
1470 Discovery of Potent Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L
Meewan, I.; Kattoula, J.; Kattoula, J.; Skinner, D.; Fajtov, P.; Giardini, M.; Woodworth, B.; McKerrow, J.; Siqueira-Neto, J.; O'Donoghue, A. J.; Abagyan, R.
10.1101/2021.10.19.465036 — pharmacology and toxicology — Posted on 2021-10-20
1480 The anterior insular cortex associates temporally discontiguous stimuli during threat learning
Namkung, H.; Lockhart, S.; de Chabot, J.; Guttman, L.; Isehak, I.; Kwon, H.-B.; Sawa, A.
10.1101/2021.10.19.465048 — neuroscience — Posted on 2021-10-20
1482 Repurposed nystatin to inhibit SARS-CoV-2 and mutants in the GI tract
Virag, E.; Seffer, D.; Penzes-Huvos, A.; Varajti, K.; Hegedus, G.; Jankovics, I.; Pallos, J. P.
10.1101/2021.10.19.464931 — pharmacology and toxicology — Posted on 2021-10-20
1484 A quantitative comparison of human embryonic and induced stem cell proteomes
Brenes, A. J.; Griesser, E. J.; Sinclair, L. V.; Jiang, H.; Yoshikawa, H.; Davidson, L.; Platani, M.; Swedlow, J.; Cantrell, D. A.; Lamond, A. I.
10.1101/2021.10.20.464767 — biochemistry — Posted on 2021-10-20
1485 Novel torin1-sensitive phosphorylation sites on the metabolic regulator AMPK revealed by label-free mass spectrometry
Smiles, W. J.; Ovens, A. J.; Yu, D.; Ling, N. X. Y.; Hoque, A.; Scott, J. W.; Galic, S.; Langendorf, C. G.; Kemp, B. E.; Petersen, J.; Oakhill, J. S.
10.1101/2021.10.20.462995 — biochemistry — Posted on 2021-10-20
1487 Intensive Single Cell Analysis Reveals Immune Cell Diversity among Healthy Individuals
Kashima, Y.; Kaneko, K.; Reteng, P.; Yoshitake, N.; Runtuwene, L. R.; Nagasawa, S.; Onishi, M.; Seki, M.; Suzuki, A.; Sugano, S.; Sakata-Yanagimoto, M.; Imai, Y.; Nakayama-Hosoya, K.; Kawana-Tachikawa, A.; Mizutani, T.; Suzuki, Y.
10.1101/2021.10.18.464926 — genomics — Posted on 2021-10-20
1489 Evolutionary trade-offs between heat and cold tolerance limit responses to fluctuating climates
Schou, M. F.; Engelbrecht, A.; Brand, Z.; Svensson, E. I.; Cloete, S.; Cornwallis, C. K.
10.1101/2021.10.20.463454 — evolutionary biology — Posted on 2021-10-20
1492 S-phase induced RNAs initiate formation of DNA replication origins
Ummarino, S.; Ebralidze, A. K.; Monteleone, E.; Zhang, Y.; Trinh, B. Q.; Di Ruscio, A.; Tenen, D. G.
10.1101/2021.10.19.465050 — molecular biology — Posted on 2021-10-20
1493 Cellular adhesion is a controlling factor in neutrophil extracellular trap formation induced by antineutrophil cytoplasmic antibodies
Lelliott, P. M.; Nishide, M.; Pavillon, N.; Okita, Y.; Shibahara, T.; Mizuno, Y.; Yoshimura, H.; Obata, S.; Kumanogoh, A.; Smith, N. I.
10.1101/2021.10.19.465054 — immunology — Posted on 2021-10-20
1495 Cortico-Subcortical Interactions in Overlapping Communities of Edge Functional Connectivity
Chumin, E. J.; Faskowitz, J.; Zamani Esfahlani, F.; Jo, Y.; Merritt, H. L.; Tanner, J. C.; Cutts, S. A.; Pope, M. E.; Sporns, O.; Betzel, R.
10.1101/2021.10.19.465016 — neuroscience — Posted on 2021-10-20
1496 On the prediction of human intelligence from neuroimaging: A systematic review of methods and reporting
Hebling Vieira, B.; Pamplona, G. S. P.; Fachinello, K.; Kamensek Silva, A.; Foss, M. P.; Garrido Salmon, C. E.
10.1101/2021.10.19.462649 — neuroscience — Posted on 2021-10-20
1498 The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder
Namkung, H.; Yukitake, H.; Fukudome, D.; Lee, B. J.; Ursin, G.; Lam, S.; Kannan, S.; Saito, A.; Niwa, M.; Sharma, K.; Zandi, P.; Jaaro-Peled, H.; Ishizuka, K.; Chatterjee, N.; Huganir, R.; Sawa, A.
10.1101/2021.10.19.465053 — neuroscience — Posted on 2021-10-20
1500 Modelling altered signalling of G-protein coupled receptors in inflamed environment to advance drug design
Ray, S.; Thies, A.; Sunkara, V.; Wulkow, H.; Celik, M. O.; Yergoez, F.; Schütte, C.; Stein, C.; Weber, M.; Winkelmann, S.
10.1101/2021.10.20.465073 — systems biology — Posted on 2021-10-20
1501 OsMADS58 stabilizes gene regulatory circuits during rice stamen development
Bai, S.-N.; Shen, L.; Tian, F.; Cheng, Z.; Zhao, Q.; Feng, Q.; Zhao, Y.; Han, B.; Fang, Y.; Lin, Y.; Chen, R.; Wang, D.; Sun, W.; Sun, J.; Zeng, H.; Yao, N.; Gao, G.; Luo, J.; Xu, Z.
10.1101/2021.10.20.465065 — plant biology — Posted on 2021-10-20
1503 Exit from quiescence couples epithelial stress amplification to fluidization
Lang, E.; Pedersen, C.; Lang, A.; Blicher, P.; Klungland, A.; Carlson, A.; Boe, S. O.
10.1101/2021.10.19.464930 — biophysics — Posted on 2021-10-20
1508 Untwisted α-synuclein Filaments formed in the Presence of Lipid Vesicles
Dasari, A. K. R.; Dillard, L.; Hojjatian, A.; Sengupta, U.; Kayed, R.; Taylor, K. A.; Borgnia, M. J.; Lim, K. H.
10.1101/2021.10.19.464986 — biochemistry — Posted on 2021-10-20
1510 Multi-hallmark long noncoding RNA maps reveal non-small cell lung cancer vulnerabilities
Esposito, R.; Polidori, T.; Meise, D.; Pulido, C.; Chouvardas, P.; Forster, S.; Schaerer, P.; Kobel, A.; Schlatter, J.; Roemmele, M.; Westemeier, E.; Zhu, L.; Lanzos, A.; Guillen-Ramirez, H.; Basile, G.; Carrozzo, I.; Vancura, A.; Ullrich, S.; Medina, P.; Andreades, A.; Harvey, D.; Ma, P.; Haefliger, S.; Wang, X.; Martinez, I.; Ochsenbein, A.; Riether, C.; Johnson, R.
10.1101/2021.10.19.464956 — genomics — Posted on 2021-10-20
1512 A kinesin-1 variant reveals motor-induced microtubule damage in cells
Budaitis, B. G.; Badieyan, S.; Yue, Y.; Blasius, T. L.; Reinemann, D. N.; Lang, M. J.; Cianfrocco, M. A.; Verhey, K. J.
10.1101/2021.10.19.464974 — cell biology — Posted on 2021-10-20
1514 T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling
Chin, S. S.; Guillen, E.; Chorro, L.; Achar, S.; Oberle, S.; Ng, K.; Alfei, F.; Zehn, D.; Altan-Bonnet, G.; DELAHAYE, F.; Lauvau, G.
10.1101/2021.10.19.464978 — immunology — Posted on 2021-10-20
1516 Pupil Dilation and Response Slowing Distinguish Deliberate Explorative Choices in the Probabilistic Learning Task
Kozunova, G.; Sayfulina, K.; Prokofyev, A.; Medvedev, V.; Rytikova, A.; Stroganova, T.; Chernyshev, B.
10.1101/2021.10.19.464963 — neuroscience — Posted on 2021-10-20
1517 Activation of SGK1.1 up-regulates the M-current in the presence of epilepsy mutations
Martin-Batista, E.; Manville, R. W.; Rivero-Perez, B.; Bartolome-Martin, D.; Alvarez de la Rosa, D.; Abbott, G. W.; Giraldez, T.
10.1101/2021.10.19.464941 — neuroscience — Posted on 2021-10-20
1519 The Respiratory Resistance Sensitivity Task: An Automated Method for Quantifying Respiratory Interoception and Metacognition
Nikolova, N.; Harrison, O. K.; Toohey, S.; Braendholt, M.; Legrand, N.; Correa, C. C.; Vejlo, M.; Jensen, M. S.; Fardo, F.; Allen, M.
10.1101/2021.10.14.464418 — neuroscience — Posted on 2021-10-20
1520 Autoantibodies against Progranulin and IL-1 receptor antagonist due to immunogenic posttranslational isoforms contribute to hyperinflammation in critically ill COVID-19
Thurner, L.; Fadle, N.; Bewarder, M.; Kos, I.; Regitz, E.; Cetin, O.; Thurner, B.; Fischer, Y.; Rixecker, T.; Preuss, K.-D.; Schormann, C.; Neumann, F.; Hartmann, S.; Bock, T.; Kaddu-Mulindwa, D.; Bette, B.; Bittenbring, J. T.; Christofyllakis, K.; Bick, A.; Lesan, V.; Abdi, Z.; Mang, S.; Becker, A.; Metz, C.; Seiler, F.; Lehmann, J.; Agne, P.; Adams, T.; Link, A.; Werner, C.; Thiel-Bodenstaff, A.; Reichert, M.; Danziger, G.; Papan, C.; Pilch, J.; Pfuhl, T.; Wuchter, P.; Herr, C.; Lohse, S.; Schrezenmeier, H.; Boehm, M.; Langer, F.; Gaebelein, G.; Friesenhahn-Ochs, B.; Lammert, F.; Koerper, S.
10.1101/2021.04.23.441188 — immunology — Posted on 2021-10-20
1521 Human enteric viruses shape disease phenotype through divergent innate immunomodulation
Adiliaghdam, F.; Amatullah, H.; Digumarthi, S.; Saunders, T. L.; Rahman, R.-U.; Wong, L. P.; Sadreyev, R.; Droit, L.; Paquette, J.; Goyette, P.; Rioux, J.; Hodin, R.; Mihindukulasuriya, K.; Handley, S. A.; Jeffrey, K. L.
10.1101/2021.10.14.464404 — immunology — Posted on 2021-10-20
1522 Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer's disease progression.
Kim, D. W.; Tu, K.; Wei, A.; Lau, A.; Gonzalez-Gil, A.; Cao, T.; Braunstein, K.; Ling, J. P.; Troncoso, J. C.; Wong, P. C.; Blackshaw, S.; Schnaar, R. L.; Li, T.
10.1101/2021.10.16.464454 — neuroscience — Posted on 2021-10-20
1523 Hybridization dynamics and extensive introgression in the Daphnia longispina species complex: new insights from a high-quality Daphnia galeata reference genome
Nickel, J. H.; Schell, T.; Holtzem, T.; Thielsch, A.; Dennis, S. R.; Schlick-Steiner, B.; Steiner, F. M.; Moest, M.; Pfenninger, M.; Schwenk, K.; Cordellier, M.
10.1101/2021.02.01.429177 — evolutionary biology — Posted on 2021-10-20
1525 Spinal ganglia control nociceptive input to the central nervous system
Han, H.; Ramli, R.; Wang, C.; Liu, C.; Shah, S.; Mullen, P.; Lall, V.; Jones, F.; Shao, J.; Zhang, H.; Jaffe, D. B.; Gamper, N.; Du, X.
10.1101/2021.07.14.452325 — neuroscience — Posted on 2021-10-20
1527 Maximally predictive ensemble dynamics from data
Costa, A. C.; Ahamed, T.; Jordan, D.; Stephens, G. J.
10.1101/2021.05.26.445816 — biophysics — Posted on 2021-10-20
1529 Rcompadre and Rage - two R packages to facilitate the use of the COMPADRE and COMADRE databases and calculation of life history traits from matrix population models
Jones, O. R.; Barks, P.; Stott, I. M.; James, T. D.; Levin, S. C.; Petry, W. K.; Capdevila, P.; Che-Castaldo, J.; Jackson, J.; Römer, G.; Schuette, C.; Thomas, C. C.; Salguero-Gomez, R.
10.1101/2021.04.26.441330 — ecology — Posted on 2021-10-20
1532 Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor-selective degradation of nucleolin
Zhang, L.; Li, L.; Wang, X.; Zhang, Y.; Xie, T.; Zhang, H.; Li, X.; Peng, T.; Sun, X.; Dai, J.; Zhou, L.; Li, H.; Liu, J.; Wu, W.; Ye, M.; Tan, W.
10.1101/2021.08.05.455211 — biochemistry — Posted on 2021-10-20
1533 Genetic and genomic architecture of species-specific cuticular hydrocarbon variation in parasitoid wasps
Buellesbach, J.; Holze, H.; Schrader, L.; Liebig, J.; Schmitt, T.; Gadau, J.; Niehuis, O.
10.1101/2021.10.18.464893 — genetics — Posted on 2021-10-20
1534 Uncovering the Genetic Architecture of Broad Antisocial Behavior through a Genome-Wide Association Study Meta-analysis.
Tielbeek, J. J.; Uffelmann, E.; Williams, B. S.; Colodro-Conde, L.; Gagnon, E.; Mallard, T. T.; Levitt, B. E.; Jansen, P. R.; Johansson, A.; Sallis, H. M.; Pistis, G.; Saunders, G. R.; Allegrini, A. G.; Rimfeld, K.; Konte, B.; Klein, M.; Hartmann, A. M.; Salvatore, J. E.; Nolte, I. M.; Demontis, D.; Malmberg, A.; Burt, S. A.; Savage, J. E.; Sugden, K.; Poulton, R.; Harris, K. M.; Vrieze, S.; McGue, M.; Iacono, W. G.; Mota, N. R.; Mill, J.; Viana, J. F.; Mitchell, B. L.; Morosoli, J. J.; Andlauer, T. F. M.; Ouellet-Morin, I.; Tremblay, R. E.; Cote, S. M.; Gouin, J.-P.; Brendgen, M. R.; Dionne,
10.1101/2021.10.19.462578 — genetics — Posted on 2021-10-20
1536 Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells
Brunsdon, H.; Brombin, A.; Peterson, S.; Postlethwait, J. H.; Patton, E. E.
10.1101/2021.09.23.461061 — cell biology — Posted on 2021-10-20
1538 Triazolopyrimidines target aerobic respiration in Mycobacterium tuberculosis
Shelton, C. D.; McNeil, M. B.; Flint, L.; Russell, D.; Berube, B.; Korkegian, A.; Ovechkina, Y.; Parish, T.
10.1101/2021.10.18.464924 — microbiology — Posted on 2021-10-20
1545 Parameter identifiability and model selection for sigmoid population growth models
Simpson, M. J.; Browning, A.; Warne, D. J.; Maclaren, O. J.; Baker, R. E.
10.1101/2021.06.22.449499 — ecology — Posted on 2021-10-20
1546 μ-opioid receptor availability is associated with sex drive in human males
Nummenmaa, L.; Jern, P.; Malen, T.; Kantonen, T.; Pekkarinen, L.; Lukkarinen, L.; Sun, L.; Nuutila, P.; Putkinen, V. J.
10.1101/2021.04.20.440432 — neuroscience — Posted on 2021-10-20
1548 Cross-border investigations on the prevalence and transmission dynamics of Cryptosporidium species in dairy cattle farms in western mainland Europe
Pinto, P.; Ribeiro, C. A.; Hoque, S.; Hammouma, O.; Leruste, H.; Detriche, S.; Canniere, E.; Daandels, Y.; Dellevoet-Groenewegen, M.; Roemen, J.; Barbier Bourgeois, A.; Kvac, M.; Follet, J.; Tsaousis, A. D.
10.1101/2021.10.18.464852 — microbiology — Posted on 2021-10-20
1549 The protein-binding pocket of Botulinum neurotoxin B accommodates a preassembled synaptotagmin / ganglioside complex
Ramirez-Franco, J.; Azzaz, F.; Sangiardi, M.; Ferracci, G.; Youssouf, F.; Popoff, M. R.; Seagar, M.; Leveque, C.; Fantini, J.; EL FAR, O.
10.1101/2021.10.18.464377 — pharmacology and toxicology — Posted on 2021-10-20
1550 The Urtica Dioica Agglutinin Prevents Rabies Virus Infection in a Muscle Explant Model
Wang, X.; Terrie, L.; Wu, G.; Damme, E. V.; Thorrez, L.; Fooks, A.; Banyard, A. C.; Neyts, J.; Jochmans, D.
10.1101/2021.05.21.441744 — pathology — Posted on 2021-10-20
1552 Condensin extrudes DNA loops in steps up to hundreds of base pairs that are generated by ATP binding events
Ryu, J.-K.; Rah, S.-H.; Janissen, R.; Kerssemakers, J. W. J.; Bonato, A.; Michieletto, D.; Dekker, C.
10.1101/2020.11.04.368506 — biophysics — Posted on 2021-10-20
1554 BioCompute Objects to communicate a viral detection pipeline with potential for use in a regulatory environment
Gulzar, N.; Keeney, J.; Baker, J. B.; Klempir, O.; Hannigan, G.; Bitton, D. A.; Maritz, J. M.; King, C. H. S.; Patel, J. A.; Duncan, P. A.; Mazumder, R.
10.1101/2021.10.19.465010 — bioinformatics — Posted on 2021-10-20
1556 Expanding the pool of public controls for GWAS via a method for combining genotypes from arrays and sequencing
Mathur, R.; Fang, F.; Gaddis, N.; Hancock, D. B.; Cho, M. H.; Hokanson, J. E.; Bierut, L. J.; Lutz, S. M.; Young, K.; Smith, A. V.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Silverman, E. K.; Page, G. P.; Johnson, E. O.
10.1101/2021.10.19.464854 — bioinformatics — Posted on 2021-10-20
1559 Ligand geometry dictates cellular and in vivo uptake of 3D DNA nanostructures
Rajwar Gada, A.; RS, S.; Vaswani, P.; Morya, V.; Barai, A.; Sen, S.; Gupta, S.; Sonawane, M.; Bhatia, D. D.
10.1101/2021.10.19.465062 — bioengineering — Posted on 2021-10-20
1560 CandyCollect: At-home saliva sampling for respiratory pathogen capture
Lee, U. N.; Su, X.; Hieber, D. L.; Tu, W.-c.; McManamen, A. M.; Chan, T. C.; Hassan, G. W.; Takezawa, M. G.; Adams, K. N.; Wald, E. R.; DeMuri, G. P.; Berthier, E.; Theberge, A. B.; Thongpang, S.
10.1101/2021.10.19.464911 — bioengineering — Posted on 2021-10-20
1561 Freestanding Hydrogel Lumens for Biological Assays
Dostie, A. M.; Lea, H. G.; Lee, U. N.; van Neel, T. L.; Berthier, E.; Theberge, A. B.
10.1101/2021.10.19.464875 — bioengineering — Posted on 2021-10-20
1562 Machine Learning Prediction of Non-Coding Variant Impact in Human Retinal Cis-Regulatory Elements
VandenBosch, L. S.; Luu, K.; Timms, A. E.; Wu, Y.; Challam, S.; Lee, A. Y.; Cherry, T. J.
10.1101/2021.10.19.464837 — genomics — Posted on 2021-10-20
1563 A within-host infection model to explore tolerance andresistance
Pierre, L.; Christine, L.; Parthuisot, N.; Faucher, C.; FERDY, J.-B.; duneau, d.
10.1101/2021.10.19.464998 — evolutionary biology — Posted on 2021-10-20
1566 Facing the green threat: A waterflea's defenses against a carnivorous plant
Kruppert, S.; Horstmann, M.; Weiss, L. C.; Barmaeva, E.; Kubitza, N.; Poppinga, S.; Westermeier, A. S.; Speck, T.; Tollrian, R.
10.1101/2021.10.19.464940 — ecology — Posted on 2021-10-20
1568 Single-Cell Analysis of Human Testis Aging, and Impact of Elevated Body Mass Index
Nie, X.; Munyoki, S. K.; Sukhwani, M.; Schmid, N.; Missel, A.; Emery, B. R.; Connect, D.; Stukenborg, J.-B.; Mayerhofer, A.; Orwig, K. E.; Aston, K. I.; Hotaling, J. M.; Cairns, B. R.; Guo, J.
10.1101/2021.10.19.464550 — developmental biology — Posted on 2021-10-20
1569 Vitrifying multiple embryos in different arrangements does not alter the cooling rate
Ostler, T.; Woolley, T. E.; Swann, K.; Thomson, A.; Palmer, G.; Priddle, H.; Kaouri, K.
10.1101/2021.05.12.443816 — developmental biology — Posted on 2021-10-20
1570 Sculpting rupture-free nuclear shapes in fibrous environments
Jana, A.; Tran, A.; Gill, A.; Kapania, R.; Konstantopoulos, K.; Nain, A.
10.1101/2021.10.19.465049 — cell biology — Posted on 2021-10-20
1572 A single-cell approach reveals variation in cellular phage-producing capacities
Kannoly, S.; Oken, G.; Shadan, J.; Musheyev, D.; Singh, K.; Singh, A.; Dennehy, J. J.
10.1101/2021.10.19.465070 — microbiology — Posted on 2021-10-20
1574 Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis
Wang, R.; Singaraju, A.; Marks, K. E.; Shakib, L.; Dunlap, G. S.; Cunningham-Bussel, A.; Chen, L.; Tirpack, A.; Fein, M. R.; Todd, D. J.; MacFarlane, L.; Goodman, S. M.; DiCarlo, E. F.; Massarotti, E. M.; Sparks, J. A.; Hamnvik, O.-P. R.; Min, L.; Jonsson, A. H.; Brenner, M. B.; Chan, K. K.; Bass, A. R.; Donlin, L. T.; Rao, D. A.
10.1101/2021.10.19.464961 — immunology — Posted on 2021-10-20
1575 Single-cell RNA sequencing uncovers the excitatory/inhibitory synaptic unbalance in the retrosplenial cortex after peripheral nerve injury
Wang, J.-H.; Wu, C.; Lian, Y.-N.; Wang, Z.-Y.; Dong, J.-j.; Wu, Q.; Liu, L.; Sun, L.; Chen, W.-J.; Chen, W.; Zhang, Z.; Zhuo, M.; Li, X.-Y.
10.1101/2021.06.09.444962 — neuroscience — Posted on 2021-10-19
1577 Quantitative MRI reveals differences in striatal myelin in children with DLD
Krishnan, S.; Cler, G.; Smith, H. J.; Willis, H. E.; Asaridou, S. S.; Healy, M. P.; Papp, D.; Watkins, K. E.
10.1101/2021.10.18.464793 — neuroscience — Posted on 2021-10-20
1578 Visual Motion Coherence Responses in Human Visual Cortex
Rina, A.; Papanikolaou, A.; Zong, X.; Papageorgiou, D. T.; Keliris, G. A.; Smirnakis, S. M.
10.1101/2021.10.18.464860 — neuroscience — Posted on 2021-10-20
1580 Overground Gait Kinematics and Muscle Activation Patterns in the Yucatan Mini Pig
Mirkiani, S.; Roszko, D. A.; O'Sullivan, C.; Faridi, P.; Hu, D. S.; Fang, D.; Everaert, D. G.; Toossi, A.; Robinson, K.; Mushahwar, V. K.
10.1101/2021.10.19.465020 — neuroscience — Posted on 2021-10-20
1585 TAP: Targeting and analysis pipeline for optimization and verification of TMS coil placement
Dannhauer, M.; Huang, Z.; Beynel, L.; Wood, E.; Bukhari-Parlakturk, N.; Peterchev, A. V.
10.1101/2021.05.09.443339 — neuroscience — Posted on 2021-10-19
1588 The maize gene maternal derepression of r1 (mdr1) encodes a DNA glycosylase with maternal and paternal fertility functions
Gent, J. I.; Swentowsky, K. W.; Higgins, K. M.; Fu, F.-F.; Zeng, Y.; Kim, D. W.; Dawe, R. K.; Springer, N. M.; Anderson, S. N.
10.1101/2021.10.04.463062 — genetics — Posted on 2021-10-19
1589 New adaptive peaks for crops - an example from improvement of drought-resilience of sorghum in Ethiopia
Birhan, T.; Dong, H.; Abajebel, N.; Wakjira, M.; Lemke, C.; Vadez, V.; Paterson, A. H.; Bantte, K.
10.1101/2021.10.18.464815 — genetics — Posted on 2021-10-19
1590 Social hosts evade predation but have deadlier parasites
Walsman, J. C.; Janecka, M. J.; Clark, D. R.; Kramp, R. D.; Rovenolt, F.; Patrick, R.; Mohammed, R. S.; Konczal, M.; Cressler, C. E.; Stephenson, J. F.
10.1101/2021.09.10.459661 — ecology — Posted on 2021-10-19
1591 RASopathy Mutations Demonstrate the Critical Function of the Cysteine-rich Domain in Maintaining BRAF in an Autoinhibited State to Prevent Aberrant Signaling
Spencer-Smith, R.; Terrell, E. M.; Insinna, C.; Agamasu, C.; Wagner, M. E.; Ritt, D. A.; Stauffer, J.; Stephen, A. G.; Morrison, D. K.
10.1101/2021.10.01.462773 — cell biology — Posted on 2021-10-19
1592 Precision localization of cellular proteins with fluorescent Fab-based probes
Liccardo, F.; Lo Monte, M.; Corrado, B.; Veneruso, M.; Celentano, S.; Coscia, M. R.; Coppola, G.; Pucci, P.; Palumbo, G.; Luini, A.; Lampe, M.; Marzullo, V. M.
10.1101/2021.10.18.464886 — cell biology — Posted on 2021-10-19
1593 Arginine methylation helps SepIVA balance regulation of septation and elongation in Mycobacterium smegmatis
Freeman, A. M.; Tembiwa, K.; Brenner, J. R.; Chase, M. R.; Fortune, S. M.; Morita, Y. S.; Boutte, C.
10.1101/2021.10.06.463415 — microbiology — Posted on 2021-10-19
1594 Genome-wide identification of tomato xylem sap fitness factors for three plant-pathogenic Ralstonia species
Georgoulis, S. J.; Shalvarjian, K. E.; Helmann, T. C.; Hamilton, C. D.; Carlson, H. K.; Deutschbauer, A. M.; Lowe-Power, T. M.
10.1101/2020.08.31.276741 — microbiology — Posted on 2021-10-19
1595 Microglia remodel the synaptic signaling required for context-dependent cognitive performance
Socodato, R.; Almeida, T. O.; Portugal, C. C.; Santos, E. C. S.; Tedim-Moreira, J.; Canedo, T.; Baptista, F.; Magalhaes, A.; Ambrosio, A. F.; Brakebusch, C.; Rubinstein, B.; Moreira, I.; Summavielle, T.; Pinto, I. M.; Relvas, J. B.
10.1101/2021.10.18.464802 — neuroscience — Posted on 2021-10-19
1596 Synaptotagmin-7 enhances phasic dopamine release
Kissiwaa, S. A.; Lebowitz, J. J.; Engeln, K. A.; Bowman, A. M.; Williams, J. T.; Jackman, S. L.
10.1101/2021.10.17.464710 — neuroscience — Posted on 2021-10-19
1600 Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium
Mehregan, A.; Perez-Conesa, S.; Zhuang, Y.; Elbahnsi, A.; Pasini, D.; Lindahl, E.; Howard, R. J.; Ulens, C.; Delemotte, L.
10.1101/2021.05.28.446179 — biophysics — Posted on 2021-10-19
1601 Genomic characterization of a lumpy skin disease virus isolated in southeast China
Ma, J.; Yuan, Y.; Shao, J.; Sun, M.; Huang, W.; Zhang, X.; He, W.; Huang, C.; Xu, W.; Qi, N.; Lin, J.; Chen, J.-M.; Sun, M.; Liu, Q.
10.1101/2021.04.27.441643 — genomics — Posted on 2021-10-19
1602 Chromosome-encoded IpaH ubiquitin ligases indicate non-human pathogenic Escherichia
Dranenko, N. O.; Tutukina, M.; Gelfand, M. S.; Kondrashov, F.; Bochkareva, O. O.
10.1101/2021.10.19.464960 — microbiology — Posted on 2021-10-19
1605 Specificities and commonalities of carbapenemase producing Escherichia coli isolated in France from 2012 to 2015.
Patino-Navarrete, R.; Rosinski-Chupin, I.; Cabanel, N.; Zongo, p.-d.; Hery, M.; Oueslati, S.; Girlich, D.; Dortet, L.; Bonnin, R.; Naas, T.; Glaser, P.
10.1101/2021.10.19.464995 — microbiology — Posted on 2021-10-19
1608 Single cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney
Dunlap, G. S.; Billi, A. C.; Ma, F.; Maz, M.; Tsoi, L. C.; Wasikowski, R.; Gudjonsson, J. E.; Kahlenberg, J. M.; Rao, D. A.
10.1101/2021.10.19.464575 — immunology — Posted on 2021-10-19
1609 Genetic Mouse Models of Autism Spectrum Disorder Present Subtle Heterogenous Cardiac Abnormalities.
Assimopoulos, S.; Hammill, C.; Fernandes, D. J.; Spencer Noakes, T. L.; Zhou, Y.-Q.; Nutter, L. M.; Ellegood, J.; Anagnostou, E.; Sled, J. G.; Lerch, J. P.
10.1101/2021.10.19.465007 — neuroscience — Posted on 2021-10-19
1614 Systematic Discovery of Antimicrobial Polymorphic Toxins
Nachmias, N.; Dotan, N.; Shalom, M.; Rivitz, A.; Shamash-Halevy, N.; Oppenheimer-Shaanan, Y.; Levy, A.
10.1101/2021.10.19.465003 — microbiology — Posted on 2021-10-19
1615 Chikungunya virus vaccine candidate incorporating synergistic mutations is attenuated and protects against virulent virus challenge
Lentscher, A. J.; McAllister, N.; Griswold, K. A.; Martin, J. L.; Welsh, O. L.; Sutherland, D. M.; Silva, L. A.; Dermody, T. S.
10.1101/2021.10.19.464869 — microbiology — Posted on 2021-10-19
1617 Opposing subclasses of Drosophila ellipsoid body neurons promote and suppress sleep
Aleman, A.; Omoto, J. J.; Singh, P.; Nguyen, B.-C.; Kandimalla, P.; Hartenstein, V.; Donlea, J. M.
10.1101/2021.10.19.464469 — neuroscience — Posted on 2021-10-19
1619 Removal of KCNQ2 from Parvalbumin-expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine
Jing, J.; Dunbar, C.; Sonesra, A.; Chavez, A.; Park, S.; Soh, H.; Lee, M.; Tzingounis, A.; Cooper, E.; Jiang, X.; Maheshwari, A.
10.1101/2020.12.09.417295 — neuroscience — Posted on 2021-10-19
1620 Fetal neural progenitors process TLR signals from bacterial components to enhance proliferation and rework brain development
Mann, B.; Crawford, J. C.; Reddy, K.; Lott, J.; Youn, Y. H.; Gao, G.; Guy, C.; Chou, C.-h.; Darnell, D.; Trivedi, S.; Bomme, P.; Loughran, A. J.; Thomas, P.; Han, Y.-G.; Tuomanen, E.
10.1101/2021.10.19.464985 — neuroscience — Posted on 2021-10-19
1622 Identification of bacterial drug-resistant cells by the convolutional neural network in transmission electron microscope images
Hayashi-Nishino, M.; Aoki, K.; Kishimoto, A.; Takeuchi, Y.; Fukushima, A.; Uchida, K.; Echigo, T.; Yagi, Y.; Hirose, M.; Iwasaki, K.; Shin'ya, E.; Washio, T.; Furusawa, C.; Nishino, K.
10.1101/2021.10.19.464925 — systems biology — Posted on 2021-10-19
1625 Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification
Tseng, H.-W.; Kulina, I.; Girard, D.; Gueguen, J.; Vaquette, C.; Salga, M.; Fleming, W.; Jose, B.; Millard, S.; Pettit, A.; Schroder, K.; Thomas, G.; Wheeler, L.; Genet, F.; Banzet, S.; Alexander, K.; Levesque, J.-P.
10.1101/2021.10.19.464906 — physiology — Posted on 2021-10-19
1626 Observation of reversal in twist-stretch coupling of RNA suggests a unified mechanism for the opposite couplings of DNA and RNA
Qiang, X.-W.; Zhang, C.; Dong, H.-L.; Tian, F.-J.; Fu, H.; Yang, Y.-J.; Dai, L.; Zhang, X.-H.; Tan, Z.-J.
10.1101/2021.10.15.464617 — biophysics — Posted on 2021-10-19
1628 Kinome state is predictive of cell viability in pancreatic cancer tumor and stroma cell lines
Berginski, M. E.; Jenner, M. R.; Joisa, C. U.; Herrera Loeza, S. G.; Golitz, B. T.; Lipner, M. B.; Leary, J. R.; Rashid, N. U.; Johnson, G. L.; Yeh, J. J.; Gomez, S. M.
10.1101/2021.07.21.451515 — bioinformatics — Posted on 2021-10-19
1630 5S-IGS rDNA in wind-pollinated trees ( Fagus L.) encapsulates 55 million years of reticulate evolution and hybrid origins of modern species
Cardoni, S.; Piredda, R.; Denk, T.; Grimm, G. W.; Papageorgiou, A. C.; Schulze, E.-D.; Scoppola, A.; Shanjani, P. S.; Suyama, Y.; Tomaru, N.; Worth, J. R. P.; Simeone, M. C.
10.1101/2021.02.26.433057 — evolutionary biology — Posted on 2021-10-19
1637 Dynamic proton-dependent motors power Type IX secretion and gliding adhesin movement in Flavobacterium
Vincent, M. S.; Comas Hervada, C.; Sebban-Kreuzer, C.; Le Guenno, H.; Chabalier, M.; Kosta, A.; Guerlesquin, F.; Mignot, T.; McBride, M.; Cascales, E.; Doan, T.
10.1101/2021.10.19.464928 — microbiology — Posted on 2021-10-19
1639 Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs with Trisomy 21
Klein, J. A.; Li, Z.; Rampam, S.; Cardini, J.; Ayoub, A.; Shaw, P.; Rachubinski, A. L.; Espinosa, J. M.; Zeldich, E.; Haydar, T.
10.1101/2021.10.19.465029 — neuroscience — Posted on 2021-10-19
1641 The landscape of extrachromosomal circular DNA in medulloblastoma
Chapman, O. S.; Luebeck, J.; Wani, S.; Tiwari, A.; Pagadala, M.; Wang, S.; Larson, J. D.; Lange, J. T.; Wong, I. T.-L.; Dehkordi, S. R.; Chandran, S.; Adam, M.; Lin, Y.; Juarez, E.; Robinson, J. T.; Sridhar, S.; Malicki, D. M.; Coufal, N.; Levy, M.; Crawford, J. R.; Pomeroy, S. L.; Rich, J.; Scheuermann, R.; Carter, H.; Dixon, J.; Mischel, P. S.; Fraenkel, E.; Wechsler-Reya, R. J.; Bafna, V.; Mesirov, J. P.; Chavez, L.
10.1101/2021.10.18.464907 — cancer biology — Posted on 2021-10-19
1642 ADAR2-repressed RNA editing: a novel mechanism contributing to t (8:21) AML leukemogenesis
Guo, M.; Chan, T. H. M.; An, O.; Song, Y.; Tan, Z. H.; Ng, V. H. E.; Cao, X.; Chng, W. J.; Osato, M.; Yang, H.; Zhou, Q.; Chen, L.; Tenen, D. G.
10.1101/2021.10.18.464918 — cancer biology — Posted on 2021-10-19
1644 High Resolution Nanostructure with Two-stages of Exponential Energy Dissipation at the Ultrathin Osteochondral Interface Tissue of Human Knee Joint
Wang, X.; Lin, J.; Li, Z.; Ma, Y.; Zhang, X.; He, Q.; Wu, Q.; Wei, W.; Yao, X.; Li, C.; Li, W.; Xie, S.; Hu, Y.; Zhang, S.; Hong, Y.; Li, X.; Chen, W.; Duan, W.; Hongwei, O.
10.1101/2021.10.18.464899 — bioengineering — Posted on 2021-10-19
1652 Profiling of Nascent Lariat Intermediates Reveals Key Genetic Determinants of the Timing of Human Co-transcriptional Splicing
Zeng, Y.; Zeng, H.; Fair, B. J.; Krishnamohan, A.; Hou, Y.; Hall, J. M.; Ruthenburg, A. J.; Li, Y. I.; Staley, J. P.
10.1101/2021.10.18.464728 — molecular biology — Posted on 2021-10-19
1653 Post-transcriptionally regulated genes are essential for pluripotent stem cell survival
Iwasaki, M.; Kawahara, Y.; Tabata, T.; Nishi, Y.; Narita, M.; Ohta, A.; Saito, H.; Yamamoto, T.; Nakagawa, M.; Yamanaka, S.; Takahashi, K.
10.1101/2021.10.18.462967 — molecular biology — Posted on 2021-10-19
1655 Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody Cocktail
Nikitin, P. A.; DiMuzio, J. M.; Dowling, J. P.; Patel, N. B.; Bingaman-Steele, J. L.; Nicolescu, C.; Heimbach, B. C.; Henriquez, N.; Polley, A.; Howanski, R. J.; Nath, M.; Shukla, H.; Finn, J. P.; Liang, L.-f.; Smith, T.; Storm, N.; McKay, L. G. A.; Johnson, R. I.; Malsick, L. E.; Honko, A. N.; Griffiths, A.; Sarma, P.; Geising, D. H.; Morin, M. J.; Robinson, M. K.
10.1101/2021.10.18.464900 — immunology — Posted on 2021-10-19
1657 Protease-controlled secretion and display of intercellular signals
Vlahos, A. E.; Kang, J.; Aldrete, C. A.; Zhu, R.; Chong, L. S.; Elowitz, M. B.; Gao, X. J.
10.1101/2021.10.18.464444 — synthetic biology — Posted on 2021-10-19
1658 Transcriptomic profiling and microsatellite identification in cobia (Rachycentron canadum), using high throughput RNA-sequencing
Aciole Barbosa, D.; Araujo, B. C.; Branco, G. S.; Simeone, A. S.; Hilsdorf, A.; Jabes, D. L.; Nunes, L. R.; Moreira, R. G.; Menegidio, F. B.
10.1101/2020.12.04.374918 — bioinformatics — Posted on 2021-10-19
1660 Genomic identification, annotation, and comparative analysis of Vacuolar-type ATP synthase subunits in Diaphorina citri
Grace, R.; Massimino, C.; Shippy, T.; Tank, W.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Benoit, J. B.; Brown, S. J.; Delia, T.; Saha, S.
10.1101/2021.10.18.464890 — bioinformatics — Posted on 2021-10-19
1661 High-throughput imaging of Caenorhabditis elegans aging using collective activity monitoring
Fouad, A. D.; Churgin, M. A.; Hayden, J.; Xu, J.; Park, J.-I.; Liu, A.; Teng, C.; Sun, H.; Parrado, M.; Bowlin, P.; de la Torre, M.; Crombie, T. A.; Sedore, C.; Coleman-Hulbert, A. L.; Johnson, E.; Phillips, P. C.; Andersen, E.; Fang-Yen, C.
10.1101/2021.10.18.464905 — bioengineering — Posted on 2021-10-19
1662 Genome-wide association study of open fieldbehavior in outbred heterogeneous stock ratsidentifies multiple loci implicated inpsychiatric disorders
Gunturkun, M. H.; Wang, T.; Chitre, A. S.; Martinez, A. G.; Holl, K.; St. Pierre, C.; Bimschleger, H.; Gao, J.; Cheng, R.; Polesskaya, O.; Solberg-Woods, L. C.; Palmer, A. A.; Chen, H.
10.1101/2021.10.18.464872 — genetics — Posted on 2021-10-19
1663 New adaptive peaks for crops - an example from improvement of drought-resilience of sorghum in Ethiopia
Dong, H.; Birhan, T.; Abajebel, N.; Wakjira, M.; Lemke, C.; Vadez, V.; Paterson, A. H.; Bantte, K.
10.1101/2021.10.18.464815 — genetics — Posted on 2021-10-19
1664 Nandrolone Decanoate supplementation promotes AMPK activation and divergent brain connectivity rearrangements in adult and aged mice.
Strogulski, N. R.; Kopczynski, A.; Girelli, V.; Carteri, R. B.; Sartor, M.; Venturin, G.; Greggio, S.; da Costa, J. C.; Rodolphi, M. S.; Portela, L. V.
10.1101/2021.10.19.465014 — neuroscience — Posted on 2021-10-19
1665 Functional connectome of brainstem nuclei involved in autonomic, limbic, pain and sensory processing in living humans from 7 Tesla resting state fMRI
Cauzzo, S.; SINGH, K.; Matthew Stauder, M.; Garcia-Gomar, M. G.; Vanello, N.; Passino, C.; Staab, J.; Indovina, I.; Bianciardi, M.
10.1101/2021.10.18.464861 — neuroscience — Posted on 2021-10-19
1667 High-throughput Evaluation of Epilepsy-associated KCNQ2 Variants Reveals Functional and Pharmacological Heterogeneity
Vanoye, C. G.; Desai, R. R.; Ji, Z.; Adusumilli, S.; Jairam, N.; Ghabra, N.; Nishtha, J.; Fitch, E.; Helbig, K.; McKnight, D.; Lindy, A.; Zou, F.; Helbig, I.; Cooper, E. C.; George, A. L.
10.1101/2021.10.18.464842 — neuroscience — Posted on 2021-10-19
1668 Functional connectome of arousal and motor brainstem nuclei in living humans by 7 Tesla resting-state fMRI
singh, k.; Cauzzo, S.; Garcia-Gomar, M. G.; Stauder, M.; Vanello, N.; Passino, C.; Bianciardi, M.
10.1101/2021.10.18.464881 — neuroscience — Posted on 2021-10-19
1670 Mitochondrial Haplogroup Association with Fasting Glucose Response in African Americans Treated with a Thiazide Diuretic
Minniefield, B. A.; Armstrong, N.; Srinivasasainagendra, V.; Tiwari, H. K.; Ballinger, S. W.; Chong, Z.; Aslibekyan, S.; Arnett, D.; Irvin, M. R.
10.1101/2021.10.18.464878 — pharmacology and toxicology — Posted on 2021-10-19
1671 BioThings SDK: a toolkit for building high-performance data APIs in biomedical research
Lelong, S.; Zhou, X.; Afrasiabi, C.; Qian, Z.; Cano, M. A.; Tsueng, G.; Xin, J.; Mullen, J.; Yao, Y.; Avila, R.; Taylor, G. K.; Su, A. I.; Wu, C.
10.1101/2021.10.18.464256 — bioinformatics — Posted on 2021-10-19
1674 An atlas of white matter anatomy, its variability, and reproducibility based on Constrained Spherical Deconvolution of diffusion MRI
Radwan, A. M.; Sunaert, S.; Schilling, K. G.; Descoteaux, M.; Landman, B. A.; Vandenbulcke, M.; Theys, T.; Dupont, P.; Emsell, L.
10.1101/2021.10.13.464139 — neuroscience — Posted on 2021-10-19
1675 Optimal Precision and Accuracy in 4Pi-STORM using Dynamic Spline PSF Models
Bates, M.; Keller-Findeisen, J.; Przybylski, A.; Hüper, A.; Stephan, T.; Ilgen, P.; Cereceda Delgado, A. R.; D'Este, E.; Jakobs, S.; Sahl, S. J.; Hell, S. W.
10.1101/2021.10.19.464803 — biophysics — Posted on 2021-10-19
1676 Single-molecule analysis of the entire perfringolysin O poreformation pathway
Mc Guinness, C.; Walsh, J.; Bayly-Jones, C.; Dunstone, M.; Morton, C.; Christie, M.; Parker, M. W.; Boecking, T.
10.1101/2021.10.19.464937 — biophysics — Posted on 2021-10-19
1679 Adjusting for Common Variant Polygenic Scores Improves Yield in Rare Variant Association Analyses
Jurgens, S. J.; Pirruccello, J. P.; Choi, S. H.; Morrill, V. N.; Chaffin, M. D.; Lubitz, S. A.; Lunetta, K. L.; Ellinor, P. T.
10.1101/2021.10.18.464866 — genomics — Posted on 2021-10-19
1682 Precision localization of cellular proteins with fluorescent Fab-based probes
Liccardo, F.; Lo Monte, M.; Corrado, B.; Veneruso, M.; Celentano, S.; Coscia, M. R.; Coppola, G.; Pucci, P.; Palumbo, G.; Luini, A.; Lampe, M.; Marzullo, V. M.
10.1101/2021.10.18.464886 — cell biology — Posted on 2021-10-19
1685 Chronic alcohol drinking persistently suppresses thalamostriatal excitation of cholinergic neurons to impair cognitive flexibility
Ma, T.; Huang, Z.; Xie, X.; Zhuang, X.; Childs, M.; Gangal, H.; Wang, X.; Smith, L. N.; Smith, R.; Zhou, Y.; Wang, J.
10.1101/2021.10.18.464867 — neuroscience — Posted on 2021-10-19
1687 Molecular atlas of the human brain vasculature at the single-cell level
Wälchli, T.; Ghobrial, M.; Schwab, M.; Takada, S.; Zhong, H.; Suntharalingham, S.; Vetiska, S.; Rodrigues Rodrigues, D.; Rehrauer, H.; Wu, R.; Yu, K.; Bisschop, J.; Farnhammer, F.; Regli, L.; Schaller, K.; Frei, K.; Ketela, T.; Bernstein, M.; Kongkham, P.; Carmeliet, P.; Valiante, T.; Dirks, P. B.; Suva, M. L.; Zadeh, G.; Tabar, V.; Schlapbach, R.; De Bock, K.; Fish, J.; Monnier, P.; Bader, G.; Radovanovic, I.
10.1101/2021.10.18.464715 — neuroscience — Posted on 2021-10-19
1688 Structural network alterations in focal and generalized epilepsy follow axes of epilepsy risk gene expression: An ENIGMA study
Lariviere, S.; Royer, J.; Rodriguez-Cruces, R.; Caligiuri, M. E.; Gambardella, A.; Concha, L.; Keller, S. S.; Cendes, F.; Yasuda, C. L.; Bonilha, L.; Gleichgerrcht, E.; Focke, N. K.; Domin, M.; von Podewills, F.; Langner, S.; Rummel, C.; Wiest, R.; Martin, P.; Kotikalapudi, R.; OBrien, T. J.; Sinclair, B.; Vivash, L.; Desmond, P. M.; Lui, E.; Vaudano, A. E.; Meletti, S.; Tondelli, M.; Alhusaini, S.; Doherty, C. P.; Cavalleri, G. L.; Delanty, N.; Kalviainen, R.; Jackson, G. D.; Kowalczyk, M.; Mascalchi, M.; Semmelroch, M.; Thomas, R. H.; Soltanian-Zadeh, H.; Davoodi-Bojd, E.; Zhang, J.; Kreilka
10.1101/2021.10.18.464713 — neuroscience — Posted on 2021-10-19
1689 Cryo-EM Structures of Amyloid-β 42 Filaments from Human Brain
Yang, Y. `; Arseni, D.; Zhang, W.; Huang, M.; Lövestam, S.; Schweighauser, M.; Kotecha, A.; Murzin, A. G.; Peak-Chew, S. Y.; Macdonald, J.; Lavenir, I.; Garringer, H. J.; Gelpi, E.; Newell, K. L.; Kovacs, G. G.; Vidal, R.; Ghetti, B.; Falcon, B.; Scheres, S.; Goedert, M.
10.1101/2021.10.19.464936 — neuroscience — Posted on 2021-10-19
1690 MIR822 modulates monosporic female gametogenesis through an ARGONAUTE9-dependent pathway in Arabidopsis thaliana
TOVAR AGUILAR, A.; GRIMANELLI, D.; Acosta Garcia, G.; Vielle Calzada, J. P.; Badillo-Corona, J. A.; Duran-Figueroa, N.
10.1101/2021.10.18.464879 — plant biology — Posted on 2021-10-19
1692 Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer.
Wellberg, E. A.; Corleto, K. A.; Checkley, L. A.; Jindal, S.; Johnson, G.; Higgins, J. A.; Obeid, S.; Anderson, S. M.; Thor, A. D.; Schedin, P. J.; MacLean, P. S.; Giles, E. D.
10.1101/2021.10.18.464856 — cancer biology — Posted on 2021-10-19
1697 Mod3D: A Low-Cost, Flexible Modular System of Live-Cell Microscopy Chambers and Holders
Bazan, C. B.; Goss, S.; Peng, C.; Begeja, N.; Suart, C.; Neuman, K.; Truant, R.
10.1101/2021.10.18.462400 — cell biology — Posted on 2021-10-19
1698 Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing's syndrome
Omar, M. H.; Byrne, D. P.; Jones, K. N.; Lakey, T. M.; Collins, K. B.; Lee, K.-S.; Daly, L. A.; Forbush, K. A.; Lau, H.-T.; Golkowski, M.; McKnight, G. S.; Breault, D. T.; Lefrancois-Martinez, A.-M.; Martinez, A.; Eyers, C. E.; Baird, G. S.; Ong, S.-E.; Smith, F. D.; Eyers, P. A.; Scott, J. D.
10.1101/2021.10.18.464848 — molecular biology — Posted on 2021-10-19
1700 Human placental bed transcriptomic profiling reveals inflammatory activation of endothelial cells in preeclampsia
Brouwers, L.; Wienke, J.; Mokry, M.; Nikkels, P. G.; Vogelvang, T. E.; Franx, A.; van Wijk, F.; van Rijn, B. B.
10.1101/2021.10.18.464811 — immunology — Posted on 2021-10-19
1701 Characterization of red fluorescent reporters for dual-color in vivo three-photon microscopy
Thornton, M. A.; Futia, G. L.; Stockton, M. E.; Ozbay, B. N.; Kilborn, K.; Restrepo, D.; Gibson, E. A.; Hughes, E. G.
10.1101/2021.10.18.464840 — neuroscience — Posted on 2021-10-19
1702 Microglia remodel the synaptic signaling required for context-dependent cognitive performance
Socodato, R.; Almeida, T. O.; Portugal, C. C.; Santos, E. C. S.; Tedim-Moreira, J.; Canedo, T.; Baptista, F.; Magalhaes, A.; Ambrosio, A. F.; Brakebusch, C.; Rubinstein, B.; Moreira, I.; Summavielle, T.; Pinto, I. M.; Relvas, J. B.
10.1101/2021.10.18.464802 — neuroscience — Posted on 2021-10-19
1704 Acute silencing uncovers multiple forms of activity-dependent neuronal survival in the mature entorhinal cortex
Zhao, R.; Grunke, S. D.; Li, M.-H.; Wood, C. A.; Perez, G. A.; Comstock, M.; Singh, A. K.; Park, K.-W.; Jankowsky, J. L.
10.1101/2021.10.18.464827 — neuroscience — Posted on 2021-10-19
1709 A method for independent estimation of false localisation rate for phosphoproteomics
Ramsbottom, K. A.; Prakash, A. A.; Perez-Riverol, Y.; Martin Camacho, O.; Martin, M.; Vizcaino, J. A.; Deutsch, E. W.; Jones, A. R.
10.1101/2021.10.18.464791 — bioinformatics — Posted on 2021-10-19
1714 Demographic model and biological adaptation inferred from the genome-wide SNP data reveal tripartite origins of southernmost Chinese Huis
He, G.; Fan, Z.-Q.; Zou, X.; Deng, X.; Yeh, H.-Y.; Wang, Z.; Liu, J.; Xu, Q.; Chen, L.; Deng, X.-H.; Wang, C.-C.; Liu, C.; Wang, M.; Liu, C.
10.1101/2021.10.18.464789 — genetics — Posted on 2021-10-19
1715 Putting pesticides on the map for pollinator research and conservation
Douglas, M. R.; Baisley, P.; Soba, S.; Kammerer, M.; Lonsdorf, E. V.; Grozinger, C. M.
10.1101/2021.10.18.464808 — ecology — Posted on 2021-10-19
1716 Microbial community dispersal in sourdough
von Gastrow, L.; Amelot, R.; Segond, D.; Guezennec, S.; Valence, F.; Sicard, D.
10.1101/2021.10.18.464797 — ecology — Posted on 2021-10-19
1717 Mass-selective and ice-free cryo-EM protein sample preparation via native electrospray ion-beam deposition
Esser, T. K.; Boehning, J.; Fremdling, P.; Agasid, M. T.; Costin, A.; Fort, K.; Konijnenberg, A.; Bahm, A.; Makarov, A.; Robinson, C. V.; Benesch, J. L. P.; Baker, L.; Bharat, T. A. M.; Gault, J.; Rauschenbach, S.
10.1101/2021.10.18.464782 — molecular biology — Posted on 2021-10-19
1718 In vivo single cell transcriptomics reveals Klebsiella pneumoniae rewiring of lung macrophages to promote infection
Dumigan, A.; Cappa, O.; Morris, B.; sa-Pessoa Graca Santos, J.; Calderon-Gonzalez, R.; Mills, G.; Lancaster, R.; Simpson, D.; Kissenpfennig, A.; Bengoechea, J. A.
10.1101/2021.10.18.464784 — microbiology — Posted on 2021-10-19
1720 All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain
Jacobsen, R. I.; Nair, R. R.; Obenhaus, H. A.; Donato, F.; Slettmoen, T.; Moser, M.-B.; Moser, E. I.
10.1101/2021.10.18.464781 — neuroscience — Posted on 2021-10-19
1723 Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity
Pogacar, Z.; Johnson, J. L.; Krenning, L.; De Conti, G.; Lieftink, C.; Velds, A.; Wardak, L.; Jochems, F.; Groot, K.; Schepers, A.; Wang, L.; Song, J.-Y.; van de Ven, M.; van Tellingen, O.; Medema, R. H.; Beijersbergen, R. L.; Bernards, R.; Leite de Oliveira, R.
10.1101/2021.10.18.464788 — cancer biology — Posted on 2021-10-19
1726 nQMaker: estimating time non-reversible amino acid substitution models
Dang, C. C.; Minh, B. Q.; McShea, H.; Masel, J.; James, J. E.; Vinh, L. S.; Lanfear, R.
10.1101/2021.10.18.464754 — bioinformatics — Posted on 2021-10-19
1730 Detecting cell-of-origin and cancer-specific features of cell-free DNA with Nanopore sequencing
Katsman, E.; Orlanski, S.; Martignano, F.; Eden, A.; Petrini, I.; Conticello, S. G.; Berman, B. P.
10.1101/2021.10.18.464684 — genomics — Posted on 2021-10-19
1731 Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding
Blumer, M.; Brown, T.; Bontempo Freitas, M.; Destro, A. L.; Oliveira, J. A.; Morales, A.; Schell, T.; Greve, C.; Pippel, M.; Jebb, D.; Hecker, N.; Ahmed, A.-W.; Kirilenko, B.; Foote, M.; Janke, A.; Lim, B. K.; Hiller, M.
10.1101/2021.10.18.462363 — evolutionary biology — Posted on 2021-10-19
1735 G-IRAE: a Generalised approach for linking the total Impact of invasion to species' Range, Abundance and per-unit Effects
Latombe, G.; Catford, J. A.; Essl, F.; Lenzner, B.; Richardson, D. M.; Wilson, J. R. U.; McGeoch, M. A.
10.1101/2021.10.18.464772 — ecology — Posted on 2021-10-19
1739 The protein-binding pocket of Botulinum neurotoxin B accommodates a preassembled synaptotagmin / ganglioside complex
Ramirez-Franco, J.; Azzaz, F.; Sangiardi, M.; Ferracci, G.; Youssouf, F.; Popoff, M. R.; Seagar, M.; Leveque, C.; Fantini, J.; EL FAR, O.
10.1101/2021.10.18.464377 — pharmacology and toxicology — Posted on 2021-10-19
1740 BugSplit: highly accurate taxonomic binning of metagenomic assemblies enables genome-resolved metagenomics
Chandrakumar, I.; Gauthier, N. P.; Nelson, C.; Bonsall, M. B.; Locher, K.; Charles, M.; MacDonald, C.; Krajden, M.; Manges, A.; Chorlton, S. D.
10.1101/2021.10.16.464647 — bioinformatics — Posted on 2021-10-19
1742 Macroevolutionary Analyses Provide New Evidences of Phasmids Wings Evolution as a Reversible Process.
Forni, G.; Martelossi, J.; Valero, P.; Hennemann, F. H.; Conle, O.; Luchetti, A.; Mantovani, B.
10.1101/2020.10.14.336354 — evolutionary biology — Posted on 2021-10-19
1743 Engineering T cell resistance to HIV-1 infection via knock-in of peptides from the heptad repeat 2 domain of gp41
Maslennikova, A.; Kruglova, N.; Kalinichenko, S.; Komkov, D.; Shepelev, M.; Golubev, D.; Siniavin, A.; Vzorov, A.; Filatov, A.; Mazurov, D.
10.1101/2021.04.30.442168 — microbiology — Posted on 2021-10-19
1744 Time scale separation of information processing between sensory and associative regions
Sorrentino, P.; Rabuffo, G.; Baselice, F.; Troisi Lopez, E.; Liparoti, M.; Quarantelli, M.; Sorrentino, G.; Bernard, C.; Jirsa, V.
10.1101/2020.10.23.350322 — neuroscience — Posted on 2021-10-19
1745 Transcriptomic profiling of atrial fibrillation canine models at disease onset
Leblanc, F. J. A.; Vahdati Hassani, F.; Qi, X.; Liesinger, L.; Naud, P.; Birner-Gruenberger, R.; Lettre, G.; Nattel, S.
10.1101/2021.02.04.429512 — genomics — Posted on 2021-10-19
1750 Zebrafish larvae as a powerful model to dissect protective innate immunity in response to Legionella pneumophila infection
Viana, F.; Boucontet, L.; Schator, D.; Laghi, V.; Ibranosyan, M.; Jarraud, S.; Colucci-Guyon, E.; Buchrieser, C.
10.1101/2021.10.18.464513 — microbiology — Posted on 2021-10-19
1752 EZTraits: a Programmable Tool to Evaluate Multi-site Deterministic Traits
Carland, M.; Bose, M.; Novkovic, B.; Pedersen, H.; Manson, C.; Lahan, S.; Pavlenko, A.; Yazdi, P. G.; Grabherr, M.
10.1101/2021.10.18.464896 — bioinformatics — Posted on 2021-10-19
1753 Interplay between positive and negative regulation by B3-type transcription factors is critical for the accurate expression of the ABA INSENSITIVE 4 gene.
Hernandez-Bernal, A. F.; Cordoba, E.; Santos Mendoza, M.; Agreda-Laguna, K. A.; Dagmara Rivera, A.; Uriostegui-Arcos, M.; Zurita, M.; Leon, P.
10.1101/2021.10.18.464865 — developmental biology — Posted on 2021-10-19
1754 Systematic analysis of membrane contact sites in Saccharomyces cerevisiae uncovers modulators of cellular lipid distribution
Castro, I. G.; Shortill, S. P.; Dziurdzik, S. K.; Cadou, A.; Ganesan, S.; Fenech, E. J.; Meyer, H.; Fadel, A.; David, Y.; Davey, M.; Mattes, C.; Valenti, R.; Ernst, R.; Zaremberg, V.; Levine, T. P.; Stefan, C.; Conibear, E.; Schuldiner, M.
10.1101/2021.10.17.464712 — cell biology — Posted on 2021-10-19
1755 ARGONAUTE proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells
Mueller, M.; Schaefer, M.; Faeh, T.; Spies, D.; Pena-Hernandez, R.; Santoro, R.; Ciaudo, C.
10.1101/2021.10.18.464771 — molecular biology — Posted on 2021-10-19
1756 Fast bacterial growth reduces antibiotic accumulation and efficacy
Łapinska, U.; Voliotis, M.; Lee, K. K.; Campey, A.; Stone, R.; Phetsang, W.; Zhang, B.; Tsaneva-Atanasova, K.; Blaskovich, M.; Pagliara, S.
10.1101/2021.10.18.464851 — microbiology — Posted on 2021-10-19
1758 The genetic architecture of language functional connectivity
Mekki, Y. N.; Guillemot, V.; Lemaitre, H.; Carrion-Castillo, A.; Forkel, S. J.; Frouin, V.; Philippe, C.
10.1101/2021.10.18.464351 — genetics — Posted on 2021-10-19
1760 Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis
Gupta, S.; Dovey, O. M.; Domingues, A. F.; Cyran, O. W.; Cash, C. M.; Giotopoulos, G.; Rak, J.; Cooper, J.; Gozdecka, M.; Asby, R. J.; Al-Jabery, N.; Hernandez-Hernandez, V.; Prabakaran, S.; Huntly, B.; Vassiliou, G. S.; Pina, C.
10.1101/2021.10.18.464824 — cancer biology — Posted on 2021-10-19
1764 Spontaneous differentiation leads to emergence of hybrid cell states relate to poor prognosis in oral cancer
Vipparthi, K.; Hari, K.; Chakraborty, P.; Ghosh, S.; Patel, A.; Ghosh, A.; Biswas, N. K.; Sharan, R.; Arun, P.; Jolly, M. K.; Singh, S.
10.1101/2021.08.24.457509 — cancer biology — Posted on 2021-10-18
1765 Genetic Diversity of Bundibugyo Ebolavirus from Uganda and the Democratic Republic of Congo
Omara, I. E.; Muyingo, S. K.; Balinandi, S.; Nyakarahuka, L.; Kiconco, J.; Kayiwa, J. T.; Mboowa, G.; Jjingo, D.; Lutwama, J. J.
10.1101/2021.10.18.464898 — genomics — Posted on 2021-10-18
1766 Epicardial transplantation of autologous atrial appendage micrografts-evaluation of safety and feasibility in pigs after coronary artery occlusion
Nummi, A.; Pätilä, T.; Mulari, S.; Lampinen, M.; Nieminen, T.; Mäyränpää, M. I.; Vento, A.; Harjula, A.; Kankuri, E.; Sari Kivistö, Erika Wilkman, Kari Teittinen, Mika Laine, Markku Kupari, Juha Sinisalo, Mat,
10.1101/2021.10.18.464894 — cell biology — Posted on 2021-10-18
1768 Self-renewing tissue-resident endothelial-macrophage progenitor cells originate from yolk sac and are a local source of inflammation and neovascularization in postnatal aorta
Williamson, A.; Toledo-Flores, D.; Liyanage, S.; Hassanshahi, M.; Dimasi, C.; Schwarz, N.; Fernando, S.; Salagaras, T.; Long, A.; Di Bartolo, B. A.; Kazenwadel, J.; Harvey, N. L.; Drummond, G. R.; Vinh, A.; Chandrakanthan, V.; Misra, A.; Tan, J. T. M.; Bonder, C. S.; Nicholls, S. J.; Bursill, C. A.; Psaltis, P. J.
10.1101/2021.10.18.464001 — cell biology — Posted on 2021-10-18
1769 Linking photoacclimation responses and microbiome shifts between depth-segregated sibling species of reef corals
Prada, C.; Lopez-Londono, T.; Pollock, F. J.; Roitman, S.; Ritchie, K. B.; Levitan, D. R.; Knowlton, N.; Woodley, C.; Iglesias-Prieto, R.; Medina, M.
10.1101/2021.10.18.464812 — microbiology — Posted on 2021-10-18
1770 Treatment with IFB-088 improves neuropathy in CMT1A and CMT1B mice
Bai, Y.; Treins, C.; Volpi, V. G.; scapin, c.; Ferri, C.; Mastrangelo, R.; Touvier, T.; Florio, F.; Bianchi, F.; Del Carro, U.; Baas, F. F.; Wang, D.; Miniou, P.; Guedat, P.; Shy, M. E.; D'Antonio, M.
10.1101/2021.10.18.464779 — neuroscience — Posted on 2021-10-18
1771 Deficiency of p38α-MAPK in myeloid cells ameliorates symptoms and pathology of APP-transgenic Alzheimer's disease mice
Luo, Q.; Schnöder, L.; Hao, W.; Litzenburger, K.; Decker, Y.; Tomic, I.; Menger, M.; Fassbender, K.; Liu, Y.
10.1101/2021.10.18.464870 — neuroscience — Posted on 2021-10-18
1773 Pathogen-derived mechanical cues regulate the spatio-temporal implementation of plant defense
Leger, O.; Garcia, F.; Khafif, M.; Leblanc-Fournier, N.; Duclos, A.; Tournat, V.; Badel, E.; Didelon, M.; Le Ru, A.; Raffaele, S.; Barbacci, A.
10.1101/2021.10.18.464859 — plant biology — Posted on 2021-10-18
1774 Therapeutic KRASG12C inhibition drives effective interferon-mediated anti-tumour immunity in immunogenic lung cancers
Mugarza, E.; van Maldegem, F.; Boumelha, J.; Moore, C.; Rana, S.; Sopena, M. L.; East, P.; Ambler, R.; Anastasiou, P.; Clavijo, P. R.; Valand, K.; Cole, M.; Molina-Arcas, M.; Downward, J.
10.1101/2021.10.18.464819 — cancer biology — Posted on 2021-10-18
1775 Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis
Gupta, S.; Dovey, O. M.; Domingues, A. F.; Cyran, O. W.; Cash, C. M.; Giotopoulos, G.; Rak, J.; Cooper, J.; Gozdecka, M.; Asby, R. J.; Al-Jabery, N.; Hernandez-Hernandez, V.; Prabakaran, S.; Huntly, B.; Pina, C.
10.1101/2021.10.18.464824 — cancer biology — Posted on 2021-10-18
1777 Cryo-ET distinguishes platelets during pre-acute myeloid leukemia from steady state hematopoiesis
Wang, Y.; Huo, T.; Tseng, Y.-J.; Dang, L.; Yu, Z.; Yu, W.; Foulks, Z.; Ludtke, S.; Nakada, D.; Wang, Z.
10.1101/2021.10.18.464863 — biophysics — Posted on 2021-10-18
1778 Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome
Liu, X.; Tong, X.; Zou, Y.; Lin, X.; Zhao, H.; Tian, L.; Jie, Z.; Wang, Q.; Zhang, Z.; Lu, H.; Xiao, L.; Qiu, X.; Zi, J.; Wang, R.; Xu, X.; Yang, H.; Wang, J.; Zong, Y.; Liu, W.; Hou, Y.; Zhu, S.; Jia, H.; Zhang, T.
10.1101/2020.06.30.181438 — genetics — Posted on 2021-10-18
1779 Experimental evolution of extremophile levels of radiation resistance in Escherichia coli
Bruckbauer, S. T.; Minkoff, B. B.; Shinohara, T.; Lipzen, A.; Guo, J.; Wood, E. A.; Sussman, M. R.; Pennacchio, C.; Cox, M. M.
10.1101/2021.10.18.464883 — evolutionary biology — Posted on 2021-10-18
1780 V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking
Schatzberg, D.; Thomas, C. F.; Reidy, P.; Hadyniak, S. E.; Skidanova, V.; Lawton, M. L.; Dojer, L.; Kitchloo, S.; Zuch, D. T.; Bradham, C. A.
10.1101/2021.10.18.464707 — developmental biology — Posted on 2021-10-18
1782 EFHD1 ablation reduces cardiac mitoflash activation and protects cardiomyocytes from ischemia.
Eberhardt, D. R.; Lee, S. H.; Yin, X.; Balynas, A. M.; Rekate, E.; Kraiss, J. N.; Lang, M. J.; Walsh, M. A.; Streiff, M. E.; Corbin, A. C.; Funai, K.; Sachse, F. B.; Chaudhuri, D.
10.1101/2021.10.18.464831 — cell biology — Posted on 2021-10-18
1785 Liposomal encapsulation of polysaccharides (LEPS) as an effective vaccine strategy to protect aged hosts against S. pneumoniae infection
Bhalla, M.; Nayerhoda, R.; Tchalla, E. Y. I.; Abamonte, A.; Park, D.; Simmons, S. R.; Pfeifer, B. A.; Bou Ghanem, E. N.
10.1101/2021.10.18.464850 — microbiology — Posted on 2021-10-18
1788 Lactate Increases Stemness of CD8+ T Cells to Augment Anti-Tumor Immunity
Feng, Q.; Liu, Z.; Yu, X.; Huang, T.; Chen, J.; Wang, J.; Wilhelm, J.; Li, S.; Song, J.; Li, W.; Sun, Z.; Sumer, B.; Li, B.; Fu, Y.-X.; Gao, J.
10.1101/2021.10.18.464724 — immunology — Posted on 2021-10-18
1789 Pathogen-derived 9-methyl sphingoid base is perceived by a lectin receptor kinase in Arabidopsis
Kato, H.; Nemoto, K.; Shimizu, M.; Abe, A.; Asai, S.; Ishihama, N.; Daimon, T.; Ojika, M.; Kawakita, K.; Onai, K.; Shirasu, K.; Ishiura, M.; Takemoto, D.; Takano, Y.; Terauchi, R.
10.1101/2021.10.18.464766 — plant biology — Posted on 2021-10-18
1790 RS-FISH: Precise, interactive, fast, and scalable FISH spot detection
Bahry, E.; Breimann, L.; Zouinkhi, M.; Epstein, L.; Kolyvanov, K.; Long, X.; Harrington, K.; Lionnet, T.; Preibisch, S.
10.1101/2021.03.09.434205 — bioinformatics — Posted on 2021-10-18
1791 Plant-based production of SARS-CoV-2 antigens for use in a subunit vaccine
Demone, J. J.; Maltseva, M.; Nourimand, M.; Nasr-Sharif, M.; Galipeau, Y.; Langlois, M.-A.; MacLean, A. M.
10.1101/2021.10.17.464700 — bioengineering — Posted on 2021-10-18
1794 Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs
Bredeson, J. V.; Mudd, A. B.; Medina-Ruiz, S.; Mitros, T.; Smith, O. K.; Miller, K. E.; Lyons, J. B.; Batra, S. S.; Park, J.; Berkoff, K. C.; Plott, C.; Grimwood, J.; Schmutz, J.; Aguirre-Figueroa, G.; Khokha, M. K.; Lane, M.; Philipp, I.; Laslo, M.; Hanken, J.; Kerdivel, G.; Buisine, N.; Sachs, L. M.; Buchholz, D. R.; Kwon, T.; Smith-Parker, H.; Gridi-Papp, M.; Ryan, M. J.; Denton, R. D.; Malone, J. H.; Wallingford, J. B.; Straight, A. F.; Heald, R.; Hockemeyer, D.; Harland, R. M.; Rokhsar, D. S.
10.1101/2021.10.18.464293 — genomics — Posted on 2021-10-18
1798 Human readaptation outpaces loss of antibiotic resistance in livestock-associated MRSA
Matuszewska, M.; Murray, G. G. R.; Ba, X.; Wood, R.; Holmes, M. A.; Weinert, L. A.
10.1101/2021.08.20.457141 — evolutionary biology — Posted on 2021-10-18
1799 Differential nuclear import sets the timing of protein access to the embryonic genome
Nguyen, T.; Costa, E.; Deibert, T.; Reyes, J.; Keber, F.; Stadlmeier, M.; Gupta, M.; Kumar, C. K.; Amodeo, A.; Gatlin, J. C.; Wuhr, M.
10.1101/2021.10.18.464816 — developmental biology — Posted on 2021-10-18
1801 Bees can be trained to identify SARS-CoV-2 infected samples.
Kontos, E.; Samimi, A.; Hakze-van der Honing, R. W.; Priem, J.; Avargues-Weber, A.; Haverkamp, A.; Dicke, M.; Gonzales, J.; van der Poel, W. H.
10.1101/2021.10.18.464814 — microbiology — Posted on 2021-10-18
1802 A peroxide-responding sRNA evolved from a peroxidase mRNA
Krieger, M. C.; Dutcher, H. A.; Ashford, A. J.; Raghavan, R.
10.1101/2021.10.18.464853 — microbiology — Posted on 2021-10-18
1804 Widespread Utilization of Diverse Organophosphate Pollutants by Marine Bacteria
Despotovic, D.; Aharon, E.; Trofimyuk, O.; Dubovetskyi, A.; Cherukuri, K. P.; Ashani, Y.; Leader, H.; Castelli, A.; Fumagalli, L.; Savidor, A.; Levin, Y.; Longo, L. M.; Segev, E.; Tawfik, D. S.
10.1101/2021.10.18.464763 — microbiology — Posted on 2021-10-18
1805 Circulatory neutrophils exhibit enhanced neutrophil extracellular trap formation in early puerperium: NETs at the nexus of thrombosis and immunity?
Giaglis, S.; Chowdhury, C. S.; Van Breda, S. V.; Stoikou, M.; Shaefer, G.; Buser, A.; Walker, U.; Lapaire, O.; Hoesli, I.; Hasler, P.; Hahn, S.
10.1101/2021.10.18.459827 — immunology — Posted on 2021-10-18
1806 Functional connectivity gradients as a common neural architecture for predictive processing in the human brain
Katsumi, Y.; Kamona, N.; Zhang, J.; Bunce, J. G.; Hutchinson, J. B.; Yarossi, M.; Tunik, E.; Quigley, K. S.; Dickerson, B. C.; Feldman Barrett, L.
10.1101/2021.09.01.456844 — neuroscience — Posted on 2021-10-18
1809 Bridge Category Models: Development of Bayesian Modelling Procedures to Account for Bridge Ordinal Ratings for Disease Staging
Levy, J.; Bobak, C. A.; Azizgolshani, N.; Andersen, M. J.; Suriawinata, A.; Liu, X.; Lisovsky, M.; Ren, B.; Christensen, B.; Vaickus, L.; O'Malley, J.
10.1101/2021.08.17.456726 — pathology — Posted on 2021-10-18
1810 PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery
Koc, S.; Lloyd, M. W.; Grover, J.; Seepo, S.; Lakshmi Subramanian, S.; Ray, M.; Frech, C.; DiGiovanna, J.; Webster, P.; Neuhauser, S.; Srivastava, A.; Yi Woo, X.; Sanderson, B. J.; White, B.; Lott, P.; PDXNet Consortium, ; Evrard, Y. A.; Wallace, T. A.; Moscow, J. A.; Doroshow, J. H.; Mitsiades, N.; Kaochar, S.; Pan, C.-x.; Chen, M. S.; Carvajal-Carmona, L.; Welm, A. L.; Welm, B. E.; Lewis, M. T.; Ramaswarmy, G.; Ding, L.; Li, S.; Herlyn, M.; Davies, M.; Roth, J.; Meric-Bernstam, F.; Robinson, P. N.; Bult, C. J.; Davis-Dusenbery, B.; Dean, D. A.; Chuang, J. H.
10.1101/2021.10.15.464537 — cancer biology — Posted on 2021-10-18
1812 Tyr is Responsible for the Cctq1a QTL and Links Developmental Environment to Central Corneal Thickness Determination
Meyer, K. J.; Larson, D. R.; Whitmore, S. S.; van der Heide, C. J.; Hedberg-Buenz, A.; Dutca, L. M.; Koli, S.; Pomernackas, N.; Mercer, H. E.; Mansaray, M. N.; Paradee, W. J.; Wang, K.; Nair, K. S.; Scheetz, T. E.; Anderson, M. G.
10.1101/2021.09.22.461410 — genetics — Posted on 2021-10-18
1814 Emergence of a novel mobile RND-type efflux pump gene cluster, tmexC3D2-toprJ1b, in Pseudomonas species
Maehana, S.; Eda, R.; Niida, N.; Hirabayashi, A.; Sakai, K.; Furukawa, T.; Sei, K.; Kitasato, H.; Suzuki, M.
10.1101/2021.07.26.453812 — microbiology — Posted on 2021-10-18
1815 Cyclic AMP signalling and glucose metabolism mediate pH taxis by African trypanosomes
Shaw, S.; Knuesel, S.; Abbuehl, D.; Naguleswaran, A.; Etzensperger, R.; Benninger, M.; Roditi, I.
10.1101/2021.01.01.424252 — microbiology — Posted on 2021-10-18
1817 Inferring system-level brain communication through multi-scale neural activity
Chang, Y.-J.; Chen, Y.-I.; Yeh, H.-C.; Carmena, J. M.; Santacruz, S. R.
10.1101/2020.11.30.404244 — neuroscience — Posted on 2021-10-18
1821 14-3-3ζ constrains insulin secretion by regulating mitochondrial function in pancreatic β-cells
Mugabo, Y.; Zhao, C.; Tan, J. J.; Ghosh, A.; Campbell, S. A.; Fadzeyeva, E.; Pare, F.; Pan, S. S.; Galipeau, M.; Ast, J.; Broichhagen, J.; Hodson, D. J.; Mulvihill, E. E.; Petropoulos, S.; Lim, G. E.
10.1101/2021.10.17.464702 — physiology — Posted on 2021-10-18
1823 Outsourced hearing in spiders by using their webs as auditory sensors
Zhou, J.; Lai, J.; Menda, G.; Stafstrom, J. A.; Miles, C. I.; Hoy, R. R.; Miles, R. N.
10.1101/2021.10.17.464740 — animal behavior and cognition — Posted on 2021-10-18
1826 Accounting for animal movement improves vaccination strategies against wildlife disease in heterogeneous landscapes
McClure, K. M.; Bastille-Rousseau, G.; Davis, A. J.; Stengel, C. A.; Nelson, K.; Chipman, R. B.; Wittemyer, G.; Abdo, Z.; Gilbert, A. T.; Pepin, K. M.
10.1101/2021.10.15.464547 — ecology — Posted on 2021-10-18
1828 Rvb1/Rvb2 proteins couple transcription and translation during glucose starvation
Chen, Y. S.; Tracy, S.; Harjono, V.; Xu, F.; Moresco, J. J.; Yates, J. R.; Zid, B. M.
10.1101/2021.10.17.464753 — molecular biology — Posted on 2021-10-18
1829 The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis
Boeck, L.; Burbaud, S.; Skwark, M. J.; Pearson, W. H.; Sangen, J.; Weimann, A.; Everall, I.; Bryant, J. M.; Malhotra, S.; Bannerman, B.; Kierdorf, K.; Blundell, T.; Dionne, M. S.; Parkhill, J.; Floto, A. R.
10.1101/2021.10.18.464689 — microbiology — Posted on 2021-10-18
1833 Decision value signals in the ventromedial prefrontal cortex andmotivational and hedonic symptoms across mood and psychotic disorders
Kang, M. S.; Wolf, D.; Kazinka, R.; Lee, S.; Ruparel, K.; Elliott, M.; Xu, A.; Cieslak, M.; Prettyman, G.; Satterthwaite, T.; Kable, J.
10.1101/2020.12.01.407197 — neuroscience — Posted on 2021-10-18
1835 The intestinal circadian clock drives microbial rhythmicity to maintain gastrointestinal homeostasis
Heddes, M.; Altaha, B.; Niu, Y.; Reitmeier, S.; Kleigrewe, K.; Haller, D.; Kiessling, S.
10.1101/2021.10.18.464061 — physiology — Posted on 2021-10-18
1836 Colon Innervating TRPA1 Positive Nociceptors Influence Mucosal Health In Mice
Bishnoi, M.; Kumar, V.; Kumar, V.; Devi, K.; Kumar, A.; Khan, R.; Singh, R. P.; Rajarammohan, S.; Kondepudi, K. K.; Chopra, K.
10.1101/2021.10.17.464752 — pharmacology and toxicology — Posted on 2021-10-18
1839 A mathematical model for electrical activity in pig atrial tissue
Peris-Yague, V.; Rubio, T.; Fakuade, F. E.; Voigt, N.; Luther, S.; Majumder, R.
10.1101/2021.10.18.464761 — biophysics — Posted on 2021-10-18
1841 Identification of age-associated proteins and functional alterations in human primary retinal pigment epithelium cells
xiuxiu, j.; Jingyang, L.; Weiping, W.; Jiangfeng, L.; Guangming, L.; Ruiqi, Q.; Mingzhu, Y.; Meng, L.; Lin, Y.; Xiaofeng, D.; Bo, L.
10.1101/2021.10.17.464744 — bioinformatics — Posted on 2021-10-18
1842 Transfer of Knowledge from Model Organisms to Evolutionarily Distant Non-Model Organisms: The Coral Pocillopora damicornis Membrane Signaling Receptome
Kumar, L.; Brenner, N.; Sledieski, S.; Olaosebikan, M.; Lynn-Goin, M.; Putnam, H.; Yang, J.; Lewinski, N.; Singh, R.; Daniels, N.; Cowen, L.; Klein-Seetharaman, J. H.
10.1101/2021.10.18.464760 — bioinformatics — Posted on 2021-10-18
1843 Nanoscopic resolution within a single imaging frame
Torres, E.; Pinto, R.; Linares, A.; Martinez, D.; Abonza, V.; Brito-Alarcon, E.; Calcines-Cruz, C.; Galindo, G.; Torres, D.; Jablonski, M.; Torres-Martinez, H. H.; Martinez, J. L.; Hernandez, H. O.; Ocelotl, J.; Garces, Y.; Barchi, M.; Dubrovsky, J. G.; Darszon, A.; Buffone, M.; Rodriguez, R.; Rendon-Mancha, J. M.; Wood, C.; Hernandez, A.; Krapf, D.; Crevenna, A. H.; Guerrero, A.
10.1101/2021.10.17.464398 — bioinformatics — Posted on 2021-10-18
1849 Aerosolization of Mycobacterium tuberculosis by tidal breathing
Dinkele, R.; Gessner, S.; McKerry, A.; Leonard, B.; Leukes, J.; Seldon, R.; Warner, D. F.; Wood, R.
10.1101/2021.10.17.464541 — microbiology — Posted on 2021-10-18
1850 Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine
Peng, K. W.; Carey, T.; Lech, P.; Vandergaast, R.; Munoz-Alia, M. A.; Packiriswamy, N.; Gnanadurai, C.; Krotova, K.; Tesfay, M.; Ziegler, C.; Haselton, M.; Sevola, K.; Lathrum, C.; Reiter, S.; Narjari, R.; Balakrishnan, B.; Suksanpaisan, L.; Sakuma, T.; Recker, J.; Zhang, L.; Waniger, S.; Russell, L.; Petro, C.; Kyratsous, C. A.; Baum, A.; Janecek, J. L.; Lee, R.; Ramachandran, S.; Graham, M.; Russell, S. J.
10.1101/2021.10.16.464660 — immunology — Posted on 2021-10-18
1852 Extrasynaptic NMDA receptors bidirectionally modulate intrinsic excitability of inhibitory neurons
zhou, q.; Yao, L.; Rong, Y.; Ma, X.; Li, H.; Deng, D.; Chen, Y.; Yang, S.; Peng, T.; Ye, T.; Liang, F.; Xu, N.
10.1101/2021.10.17.464733 — neuroscience — Posted on 2021-10-18
1854 A common neural currency account for social and non-social decisions
Arabadzhiyska, D. H.; Garrod, O. G. B.; Fouragnan, E. F.; De Luca, E.; Schyns, P. G.; Philiastides, M. G.
10.1101/2021.10.18.464762 — neuroscience — Posted on 2021-10-18
1855 HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
Kim, J.; Park, J.; Kim, H.; Son, N.; Lambing, C.; Kim, E.-J.; Kim, J.; Byun, D.; Lee, Y.; Park, Y. M.; Nageswaran, D. C.; Kuo, P.; Dang, T. V. T.; Hwang, I.; Henderson, I. R.; Choi, K.
10.1101/2021.10.17.464477 — plant biology — Posted on 2021-10-18
1856 Elevated islet prohormone ratios as indicators of insulin dependency in islet transplant recipients
Chen, Y.-C.; Klimek-Abercrombie, A. M.; Potter, K. J.; Pallo, L. P.; Soukhatcheva, G.; Lei, D.; Bellin, M.; Verchere, C. B.
10.1101/2021.10.17.464749 — pathology — Posted on 2021-10-18
1858 RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine
Wood, E. C.; Glen, A. K.; Kvarfordt, L. G.; Womack, F.; Acevedo, L.; Yoon, T. S.; Ma, C.; Flores, V.; Sinha, M.; Roach, J. C.; Mendoza, L.; Hoffman, A. S.; Deutsch, E. W.; Koslicki, D.; Ramsey, S. A.
10.1101/2021.10.17.464747 — bioinformatics — Posted on 2021-10-18
1860 SIMBA: SIngle-cell eMBedding Along with features
Chen, H.; Ryu, J.; Vinyard, M. E.; Lerer, A.; Pinello, L.
10.1101/2021.10.17.464750 — bioinformatics — Posted on 2021-10-18
1861 Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection
Zhang, Q.; Radvak, P.; Lee, J.; Xu, Y.; Cao-Dao, V.; Xu, M.; Zheng, W.; Chen, C. Z.; Xie, H.; Ye, Y.
10.1101/2021.10.15.464595 — cell biology — Posted on 2021-10-18
1862 Source-sink connectivity: a novel resting-state EEG marker of the epileptogenic zone
Gunnarsdottir, K. M.; Li, A.; Smith, R. J.; Kang, J.-Y.; Crone, N.; Korzeniewska, A.; Rouse, A. G.; Cameron, N.; Cajigas, I.; Inati, S.; Zaghloul, K. A.; Boerwinkle, V.; Wyckoff, S.; Barot, N.; Elarjani, T.; Bicchi, M. M.; Gonzalez-Martinez, J.; Sarma, S. V.
10.1101/2021.10.15.464594 — bioengineering — Posted on 2021-10-18
1863 Open Science Discovery of Oral Non-Covalent SARS-CoV-2 Main Protease Inhibitor Therapeutics
The COVID Moonshot Consortium, ; Achdout, H.; Aimon, A.; Bar-David, E.; Barr, H.; Ben-Shmuel, A.; Bennett, J.; Boby, M. L.; Borden, B.; Bowman, G. R.; Brun, J.; BVNBS, S.; Calmiano, M.; Carbery, A.; Cattermole, E.; Chernyshenko, E.; Chodera, J. D.; Clyde, A.; Coffland, J. E.; Cohen, G.; Cole, J.; Contini, A.; Cox, L.; Cvitkovic, M.; Dias, A.; Donckers, K.; Dotson, D. L.; Douangamath, A.; Duberstein, S.; Dudgeon, T.; Dunnett, L.; Eastman, P. K.; Erez, N.; Eyermann, C. J.; Fairhead, M.; Fate, G.; Fearon, D.; Fedorov, O.; Ferla, M.; Fernandes, R. S.; Ferrins, L.; Foster, R.; Foster, H.; Gabizon,
10.1101/2020.10.29.339317 — biochemistry — Posted on 2021-10-18
1866 Alone Again: Altered Activation in the Observation Execution System during Synchronization in High Loneliness Individuals
Saporta, N.; Scheele, D.; Lieberz, J.; Nevat, M.; Kanterman, A.; Hurlemann, R.; Shamay-Tsoory, S. G.
10.1101/2021.10.17.464634 — neuroscience — Posted on 2021-10-18
1867 Global population genomics of two subspecies of Cryptosporidium hominis during 500 years of evolution
Tichkule, S.; Caccio, S. M.; Robinson, G.; Chalmers, R. M.; Mueller, I.; Emery-Corbin, S. J.; Eibach, D.; Tyler, K. M.; van Oosterhout, C.; Jex, A.
10.1101/2021.09.09.459610 — genomics — Posted on 2021-10-18
1869 Effects of early and late life environments on ageing
Sanghvi, K.; Iglesias-Carrasco, M.; Zajitschek, F.; Kruuk, L.; Head, M. L.
10.1101/2021.10.15.464502 — evolutionary biology — Posted on 2021-10-18
1870 The prion and HSP104 modulate cytochrome c oxidase deficiency caused by deletion of COX12
Saini, P. K.; Dawitz, H.; Aufschnaiter, A.; Thomas, J.; Amblard, A.; Stewart, J.; Thierry-Mieg, N.; Ott, M.; Pierrel, F.
10.1101/2021.10.08.463630 — cell biology — Posted on 2021-10-18
1871 Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death
Margreiter, M. A.; Witzenberger, M.; Wasser, Y.; Davydova, E.; Janowski, R.; Sobisch, C.; Metz, J.; Poma, B.; Paolomino-Hernandez, O.; Habib, P.; Wagner, M.; Carell, T.; Shah, J.; Schulz, J. B.; Niessing, D.; Voigt, A.; Rossetti, G.
10.1101/2021.05.03.442419 — molecular biology — Posted on 2021-10-18
1872 Large-scale comparative genomics unravels great genomic diversity across the Rickettsia and Ca. Megaira genera and identifies Torix group as an evolutionarily distinct clade.
Davison, H. R.; Pilgrim, J.; Wybouw, N.; Parker, J.; Pirro, S.; Hunter-Barnett, S.; Campbell, P. M.; Blow, F.; Darby, A. C.; Hurst, G. D. D.; Siozios, S.
10.1101/2021.10.06.463315 — microbiology — Posted on 2021-10-18
1878 Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks
Dudek, M.; Pathiranage, D.; Goncalves, C. F.; Lawless, C.; Wang, D.; Luo, Z.; Yang, L.; Guilak, F.; Hoyland, J. A.; Meng, Q.-J.
10.1101/2021.10.01.462769 — physiology — Posted on 2021-10-18
1880 How low can you go? Driving down the DNA input requirements for nanopore sequencing
Heavens, D.; Chooneea, D.; Giolai, M.; Cuber, P.; Aanstad, P.; Martin, S.; Alston, M.; Misra, R.; Clark, M. D.; Leggett, R. M.
10.1101/2021.10.15.464554 — genomics — Posted on 2021-10-18
1883 Soil causes gut microbiota to flourish and total serum IgE levels to decrease in mice
Zhou, D.; Li, N.; Yang, F.; Zhang, H.; Bai, Z.; Dong, Y.; Li, M.; Zhu, W.; Fei, Z.; Xiao, P.; Xiao, S.; Lu, Z.
10.1101/2021.01.25.428035 — ecology — Posted on 2021-10-18
1884 Wild cereal grain consumption among Early Holocene foragers of the Balkans predates the arrival of agriculture
Cristiani, E.; Radini, A.; Zupancich, A.; Gismondi, A.; D'Agostino, A.; Ottoni, C.; Carra, M.; Vukojizic, S.; Constantinescu, M.; Antonovic, D.; Price, T. D.; Boric, D.
10.1101/2021.10.14.464411 — ecology — Posted on 2021-10-18
1885 The temporal balance between self-renewal and differentiation of human neural stem cells requires the Amyloid Precursor Protein
Shabani, K.; Pigeon, J.; Benaissa Touil Zariouh, M.; Liu, T.; Saffarian, A.; Komatsu, J.; Liu, E.; Danda, N.; Limame, R.; Bohl, D.; Parras, C.; Hassan, B. A.
10.1101/2021.02.17.431707 — neuroscience — Posted on 2021-10-18
1886 Alpha fluctuations regulate the accrual of visual information to awareness
Torralba Cuello, M.; Drew, A.; Sabate San Jose, A.; Moris Fernandez, L.; Soto Faraco, S.
10.1101/2020.09.16.298166 — neuroscience — Posted on 2021-10-18
1887 Neurexins Regulate GABA Co-release by Dopamine Neurons
Ducrot, C.; de Carvalho, G.; Delignat-Lavaud, B.; Delmas, C.; Giguere, N.; Mukherjee, S.; Burke, S.; Bourque, M.-J.; Parent, M.; Chen, L. Y.; Trudeau, L.-E.
10.1101/2021.10.17.464666 — neuroscience — Posted on 2021-10-17
1891 Comparative genomics of Xylella fastidiosa suggests determinants of host-specificity and expands its mobile genetic elements repertoire
Uceda-Campos, G.; Feitosa-Junior, O. R.; Santiago, C. R. N.; Pierry, P. M.; Zaini, P. A.; de Santana, W. O.; Martins-Junior, J.; Barbosa, D.; Digiampietri, L. A.; Setubal, J. C.; da Silva, A. M.
10.1101/2021.10.17.464729 — genomics — Posted on 2021-10-17
1892 Combining metabolomics and experimental evolution reveals key mechanisms underlying longevity differences in laboratory evolved Drosophila melanogaster populations
Phillips, M.; Arnold, K. R.; Vue, Z.; Beasley, H.; Garza Lopez, E.; Marshall, A.; Morton, D.; McReynolds, M. R.; Barter, T. T.; Hinton, A.
10.1101/2021.10.16.464668 — evolutionary biology — Posted on 2021-10-17
1896 Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1
Jones, A. N.; Grass, C.; Meininger, I.; Geerlof, A.; Klostermann, M.; Zarnack, K.; Krappmann, D.; Sattler, M.
10.1101/2021.10.12.464102 — biochemistry — Posted on 2021-10-17
1897 The genome of the camphor tree and the genetic and climatic relevance of the top-geoherbalism in this medicinal plant
Jiang, R.; Chen, X.; Liao, X.; Peng, D.; Han, X.; Zhu, C.; Wang, P.; Hufnagel, D.; Li, C.; Li, K.; Wang, L.
10.1101/2021.10.17.464679 — genomics — Posted on 2021-10-17
1901 Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
Meyers, A. K.; Wang, Z.; Han, W.; Zhao, Q.; Zabalawi, M.; Liu, J.; Manne, R. K.; Lin, H.-K.; Furdui, C. M.; Locasale, J. W.; McCall, C. M.; Zhu, X.
10.1101/2021.10.02.462869 — immunology — Posted on 2021-10-17
1902 A Mediterranean-like fat blend protects against the development of severe colitis in the mucin-2 deficient murine model
Haskey, N.; Ye, J.; Estaki, M.; Verdugo-Meza, A.; Barnett, J. A.; Yousefi, M.; Birnie, B.; Gruenheid, S.; Ghosh, S.; Gibson, D. L.
10.1101/2021.09.27.462042 — immunology — Posted on 2021-10-17
1904 The cerebellum contributes to tonic-clonic seizures by altering neuronal activity in the ventral posteromedial nucleus (VPM) of the thalamus
Beckinghausen, J.; Ortiz-Guzman, J.; Lin, T.; Bachman, B.; Liu, Y.; Heck, D. H.; Arenkiel, B. R.; Sillitoe, R. V.
10.1101/2021.10.03.462953 — neuroscience — Posted on 2021-10-17
1906 T7Max transcription system
Deich, C.; Cash, B.; Sato, W.; Sharon, J.; Aufdembrink, L.; Gaut, N. J.; Heili, J.; Stokes, K.; Engelhart, A. E.; Adamala, K. P.
10.1101/2021.10.17.464727 — synthetic biology — Posted on 2021-10-17
1907 Transcriptional Regulation of Synthetic Polymer Networks
Graham, A. J.; Dundas, C. M.; Partipilo, G.; Miniel Mahfoud, I. E.; FitzSimons, T.; Rinehart, R.; Chiu, D.; Tyndall, A. E.; Rosales, A. M.; Keitz, B. K.
10.1101/2021.10.17.464678 — synthetic biology — Posted on 2021-10-17
1910 A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis
Nomoto, Y.; Takatsuka, H.; Yamada, K.; Suzuki, T.; Suzuki, T.; Huang, Y.; Latrasse, D.; An, J.; Gombos, M.; Breuer, C.; Ishida, T.; Maeo, K.; Imamura, M.; Yamashino, T.; Sugimoto, K.; Magyar, Z.; Bogre, L.; Raynaud, C.; Benhamed, M.; Ito, M.
10.1101/2021.10.16.464643 — plant biology — Posted on 2021-10-17
1911 Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death
Law, M. E.; Yaaghubi, E.; Ghilardi, A.; Davis, B. J.; Ferreira, R. B.; Koh, J.; Chen, S.; DePeter, S. F.; Schilson, C. M.; Chiang, C.-W.; Heldermon, C. D.; Norgaard, P.; Castellano, R. K.; Law, B. K.
10.1101/2021.01.13.426390 — pharmacology and toxicology — Posted on 2021-10-17
1912 Repurposing Tranexamic Acid as an Anticancer Agent
Law, M. E.; Davis, B. J.; Ghilardi, A. F.; Yaaghubi, E.; Dulloo, Z. M.; Wang, M.; Guryanova, O.; Heldermon, C. D.; Castellano, R. K.; Law, B. K.
10.1101/2021.10.17.464714 — cancer biology — Posted on 2021-10-17
1913 The ASCC2 CUE domain contacts adjacent ubiquitins to recognize K63-linked polyubiquitin
Lombardi, P. M.; Haile, S.; Rusanov, T.; Rodell, R.; Anoh, R.; Baer, J. G.; Burke, K. A.; Gray, L. N.; Hacker, A. R.; Kebreau, K. R.; Ngandu, C. K.; Orland, H. A.; Osei-Asante, E.; Schmelyun, D. P.; Shorb, D. E.; Syed, S. H.; Veilleux, J. M.; Majumdar, A.; Mosammaparast, N.; Wolberger, C.
10.1101/2021.10.17.464694 — biophysics — Posted on 2021-10-17
1919 Hair phenotype diversity across Indriidae lemurs
Tapanes, E.; Jacobs, R. L.; Harryman, I.; Louis, E. E.; Irwin, M. T.; Kamilar, J. M.; Bradley, B. J.
10.1101/2021.10.16.464615 — evolutionary biology — Posted on 2021-10-17
1920 Combining metabolomics and experimental evolution reveals key mechanisms underlying longevity differences in laboratory evolved Drosophila melanogaster populations
Phillips, M.; Arnold, K. R.; Vue, Z.; Beasley, H.; Garza Lopez, E.; Marshall, A.; Morton, D.; McReynolds, M. R.; Barter, T. T.; Hinton, A.
10.1101/2021.10.16.464668 — evolutionary biology — Posted on 2021-10-17
1921 Tuberin levels during cellular differentiation in brain development
Abu Khatir, B.; Davis, G. O.; Sameem, M.; Patel, R.; Fong, J.; Lubanska, D.; Fidalgo da Silva, E.; Porter, L. A.
10.1101/2021.10.17.464725 — developmental biology — Posted on 2021-10-17
1922 The ESX-1 secretion system senses bacterial contact and prepares mycobacteria for environmental adaptation
Herrera, N.; Odermatt, P. D.; Voorhies, M.; Nakagawa, R.; Sil, A.; Chang, F.; Rosenberg, O. S.
10.1101/2021.10.17.464699 — microbiology — Posted on 2021-10-17
1923 Insight in the quorum sensing-driven lifestyle of the non-pathogenic Agrobacterium tumefaciens 6N2 and the interactions with the yeast Meyerozyma guilliermondii
Bertini, E. V.; Torres, M. A.; Leger, T.; Garcia, C.; Hong, K.-W.; Chong, T. M.; Castellanos de Figueroa, L. I.; Chan, K.-G.; Dessaux, Y.; Camadro, J.-M.; Nieto-Penalver, C. G.
10.1101/2021.10.17.464673 — microbiology — Posted on 2021-10-17
1927 Synaptotagmin-7 enhances phasic dopamine release
Jackman, S. L.; Kissiwaa, S. A.; Lebowitz, J. J.; Engeln, K. A.; Bowman, A. M.; Williams, J. T.
10.1101/2021.10.17.464710 — neuroscience — Posted on 2021-10-17
1928 14-3-3ζ constrains insulin secretion in pancreatic β-cells by regulating mitochondrial function
Mugabo, Y.; Zhao, C.; Tan, J. J.; Ghosh, A.; Campbell, S. A.; Fadzeyeva, E.; Pare, F.; Pan, S. S.; Galipeau, M.; Ast, J.; Broichhagen, J.; Hodson, D. J.; Mulvihill, E. E.; Petropoulos, S.; Lim, G. E.
10.1101/2021.10.17.464702 — physiology — Posted on 2021-10-17
1929 RNA Helix Thermodynamics: The End Game
Zuber, J.; Schroeder, S. J.; Sun, H.; Turner, D. H.; Mathews, D. H.
10.1101/2021.10.16.464667 — biophysics — Posted on 2021-10-17
1930 Augmented Transcutaneous Stimulation Using an Injectable Electrode
Verma, N.; Graham, R. D.; Mudge, J.; Trevathan, J. K.; Franke, M.; Shoffstall, A. J.; Williams, J.; Dalrymple, A. N.; Fisher, L. E.; Weber, D. J.; Lempka, S. F.; Ludwig, K. A.
10.1101/2021.09.29.462482 — bioengineering — Posted on 2021-10-17
1931 Supercharged Cellulases Show Reduced Non-Productive Binding, But Enhanced Activity, on Pretreated Lignocellulosic Biomass
Nemmaru, B.; Douglass, J.; Yarbrough, J. M.; De Chellis, A.; Shankar, S.; Thokkadam, A.; Wang, A.; Chundawat, S. P. S.
10.1101/2021.10.17.464688 — bioengineering — Posted on 2021-10-17
1933 Identification of multi-omics molecular signature of acute radiation injury using nonhuman primate model
Cheema, A.; Li, Y.; Moulton, J.; Girgis, M.; Wise, S. Y.; Carpenter, A.; Fatanmi, O. O.; Singh, V. K.
10.1101/2021.10.16.464661 — biochemistry — Posted on 2021-10-17
1934 In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains
van den Hoek, H.; Klena, N.; Jordan, M. A.; Alvarez Viar, G.; Schaffer, M.; Erdmann, P. S.; Wan, W.; Plitzko, J. M.; Baumeister, W.; Pigino, G.; Hamel, V.; Guichard, P.; Engel, B. D.
10.1101/2021.10.17.464685 — cell biology — Posted on 2021-10-17
1936 Acoustic regularities in infant-directed speech and song across cultures
Hilton, C. B.; Moser, C. J.; Bertolo, M.; Lee-Rubin, H.; Amir, D.; Bainbridge, C. M.; Simson, J.; Knox, D.; Glowacki, L.; Galbarczyk, A.; Jasienska, G.; Ross, C.; Neff, M. B.; Martin, A.; Cirelli, L. K.; Trehub, S. E.; Song, J.; Kim, M.; Schachner, A.; Vardy, T. A.; Atkinson, Q. D.; Antfolk, J.; Madhivanan, P.; Siddaiah, A.; Placek, C. D.; Salali, G. D.; Keestra, S.; Singh, M.; Collins, S. A.; Patton, J. Q.; Scaff, C.; Stieglitz, J.; Moya, C.; Sagar, R. R.; Wood, B. M.; Krasnow, M. M.; Mehr, S. A.
10.1101/2020.04.09.032995 — animal behavior and cognition — Posted on 2021-10-17
1937 Bifurcating Neurons In The Anterior Thalamic Nuclei
Pei, Y.; Tasananukorn, S.; Wolff, M.; Dalrymple-Alford, J. C.
10.1101/2021.08.21.457238 — neuroscience — Posted on 2021-10-17
1939 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.
10.1101/2020.11.27.399857 — genomics — Posted on 2021-10-17
1940 Opposing roles of blood-borne monocytes and tissue-resident macrophages in limbal stem cell damage after ocular injury
Zhou, C.; Lei, F.; Mittermaier, M.; Ksander, B.; Dana, R.; Dohlman, C. H.; Vavvas, D. G.; Chodosh, J.; Paschalis, E. I.
10.1101/2021.07.25.453707 — immunology — Posted on 2021-10-17
1943 Photoacoustic-MR Images Registration Based on Co-Sparse Analysis Model to Compensate for Brain Shift
Farnia, P.; Makkiiabadi, B.; Alimohammadi, M.; Najafzadeh, E.; Basij, M.; Yan, Y.; Mehrmohammadi, M.; Ahmadian, A.
10.1101/2021.07.28.453095 — bioengineering — Posted on 2021-10-17
1944 Long-term evolution of antibiotic persistence in P. aeruginosa lung infections
Ghoul, M.; Andersen, S. B.; Johansen, H. K.; Jelsbak, L.; Molin, S.; Perron, G.; Griffin, A. S.
10.1101/2021.10.14.464434 — evolutionary biology — Posted on 2021-10-17
1948 Disentangling the flow of signals between populations of neurons
Gokcen, E.; Jasper, A. I.; Semedo, J. D.; Zandvakili, A.; Kohn, A.; Machens, C. K.; Yu, B. M.
10.1101/2021.08.30.458230 — neuroscience — Posted on 2021-10-16
1950 Interferon-Gamma Signaling Promotes Melanoma Progression and Metastasis
Zhou, B.; Basu, J.; Kazmi, H. R.; Mo, X.; Preston-Alp, S.; Cai, K. Q.; Kappes, D.; Zaidi, M. R.
10.1101/2021.10.14.464463 — cancer biology — Posted on 2021-10-16
1954 Deep deconvolution of the hematopoietic stem cell regulatory microenvironment reveals a high degree of specialization and conservation between mouse and human.
Ye, J.; Calvo, I. A.; Cenzano, I.; Vilas-Zornoza, A.; Martinez-de-Morentin, X.; Lasaga, M.; Alignani, D.; Pavia, B.; Vinado, A. C.; San Martin-Uriz, P.; Romero, J. P.; Quilez Agreda, D.; MinanaBarrios, M.; Sancho-Gonzalez, I.; Todisco, G.; Malcovati, L.; Planell, N.; Saez, B.; Tegner, J.; Prosper, F.; Gomez-Cabrero, D.
10.1101/2021.07.17.452614 — immunology — Posted on 2021-10-16
1956 Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches
Guilliams, M.; Bonnardel, J.; Haest, B.; Vanderborght, B.; Bujko, A.; Martens, L.; Thone, T.; Browaeys, R.; De Ponti, F. F.; Remmerie, A.; Wagner, C.; Vanneste, B.; Zwicker, C.; Vanhalewyn, T.; Goncalves, A.; Lippens, S.; Devriendt, B.; Cox, E.; Ferrero, G.; Wittamer, V.; Willaert, A.; Kaptein, S. J.; Neyts, J.; Dallmeier, K.; Geldhof, P.; Casaert, S.; Deplancke, B.; ten Dijke, P.; Hoorens, A.; Vanlander, A.; Berrevoet, F.; Van Nieuwenhove, Y.; Saeys, Y.; Saelens, W.; Van Vlierberghe, H.; Devisscher, L.; Scott, C. L.
10.1101/2021.10.15.464432 — immunology — Posted on 2021-10-16
1964 Ionizing radiation improves RIG-I mediated immunotherapy through enhanced p53 activation in malignant melanoma
Lambing, S.; Holdenrieder, S.; Müller, P.; Hagen, C.; Garbe, S.; Schlee, M.; van den Boorn, J. G.; Bartok, E.; Hartmann, G.; Renn, M.
10.1101/2021.10.16.464638 — immunology — Posted on 2021-10-16
1966 Long-term imaging of the ventral nerve cord in behaving adult Drosophila
Ramdya, P.; Hermans, L.; Kaynak, M.; Braun, J.; Lobato-Rios, V.; Chen, C.-L.; Gunel, S.; Aymanns, F.; Sakar, M. S.
10.1101/2021.10.15.463778 — neuroscience — Posted on 2021-10-16
1967 Single-cell transcriptomics unveils xylem cell development and evolution
Tung, C.-C.; Kuo, S.-C.; Yang, C.-L.; Huang, C.-E.; Yu, J.-H.; Sun, Y.-H.; Shuai, P.; Su, J.-C.; Ku, C.; Lin, Y.-C. J.
10.1101/2021.10.16.464627 — plant biology — Posted on 2021-10-16
1968 Blood flow synchronization in renal microcirculation - a high-resolution imaging study.
Postnov, D. D.; Marsh, D.; Cupples, W.; Holstein-Rathlou, N.-H.; Sosnovtseva, O.
10.1101/2021.10.15.464509 — physiology — Posted on 2021-10-16
1970 iHypoxia: an integrative database of the expression dynamics of proteins in response to hypoxia in animals
Liu, Z.-X.; Wang, P.; Zhang, Q.; Li, S.; Zhang, Y.; Guo, Y.; Jia, C.; Shao, T.; Li, L.; Wang, Z.; Cheng, H.
10.1101/2021.10.16.464637 — bioinformatics — Posted on 2021-10-16
1973 Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity
Liu, H.; Ling, W.; Hua, X.; Moon, J.-Y.; Williams-Nguyen, J. S.; Zhan, X.; Plantinga, A. M.; Zhao, N.; Zhang, A.; Knight, R.; Qi, Q.; Burk, R. D.; Kaplan, R. C.; Wu, M. C.
10.1101/2021.10.15.464608 — genomics — Posted on 2021-10-16
1974 Genomic insights into the population history and biological adaptation of Southwestern Chinese Hmong-Mien people
Yan Liu, Y.; Wang, M.; Liu, C.; Zhu, J.; Zou, X.; Li, W.; Lin Wang, L.; Leng, C.; Xu, Q.; Yeh, H.-Y.; Wang, C.-C.; Wen, X.; Liu, C.; He, G.
10.1101/2021.10.16.463767 — genetics — Posted on 2021-10-16
1975 Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
Zito, A.; Roberts, A. L.; Visconti, A.; Rossi, N.; Andres-Ejarque, R.; Nardone, S.; El-Sayed Moustafa, J. S.; Falchi, M.; Small, K. S.
10.1101/2021.10.15.463586 — genetics — Posted on 2021-10-16
1976 When are bacteria really gazelles? Comparing patchy ecologies with dimensionless numbers
Urmy, S. S.; Cramer, A. N.; Rogers, T. L.; Sullivan-Stack, J.; Schmidt, M. L.; Stewart, S. D.; Symons, C. C.
10.1101/2021.10.15.464607 — ecology — Posted on 2021-10-16
1977 Intermittent fasting induces rapid hepatocyte proliferation
Sarkar, A.; Jin, Y.; Anbarchian, T.; Yang, Y.; Nguyen, H.; Rulifson, E.; Fish, M.; Logan, C. Y.; Kaye, A.; Wu, P.; Nusse, R.
10.1101/2021.10.16.464650 — cell biology — Posted on 2021-10-16
1980 Characterisation of the phase-variable autotransporter Lav reveals a role in host cell adherence and biofilm formation in Non-Typeable Haemophilus influenzae
Phillips, Z. N.; Garai, P.; Tram, G.; Husna, A.-U.; Staples, M.; Grimwood, K.; Jennison, A.; Jennings, M. P.; Brockman, K.; Atack, J. M.
10.1101/2021.10.15.464623 — microbiology — Posted on 2021-10-16
1983 Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer's disease progression.
Kim, D. W.; Tu, K.; Wei, A.; Lau, A.; Gonzalez-Gil, A.; Cao, T.; Braunstein, K.; Ling, J. P.; Troncoso, J. C.; Wong, P. C.; Blackshaw, S.; Schnaar, R. L.; Li, T.
10.1101/2021.10.16.464454 — neuroscience — Posted on 2021-10-16
1984 Dorsolateral prefrontal cortex supports speech perception in listeners with cochlear implants
Sherafati, A.; Dwyer, N.; Bajracharya, A.; Hassanpour, M. S.; Eggebrecht, A. T.; Firszt, J. B.; Culver, J. P.; Peelle, J. E.
10.1101/2021.10.16.464654 — neuroscience — Posted on 2021-10-16
1985 Genome scale modeling of the protein secretory pathway reveals novel targets for improved recombinant protein production in yeast
Li, F.; Chen, Y.; Qi, Q.; Wang, Y.; Yuan, L.; Huang, M.; Elsemman, I. E.; Feizi, A.; Kerkhoven, E. J.; Nielsen, J.
10.1101/2021.10.16.464630 — systems biology — Posted on 2021-10-16
1987 A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation
Mackay, C. E.; Floen, M.; Leo, M. D.; Hasan, R.; Fernandez-Pena, C.; Singh, P.; Malik, K. U.; Jaggar, J. H.
10.1101/2021.10.16.464653 — physiology — Posted on 2021-10-16
1994 scTriangulate: Decision-level integration of multimodal single-cell data
Li, G.; Baobao, S.; Grimes, H. L.; Prasath, V. B. S.; Salomonis, N. L.
10.1101/2021.10.16.464640 — bioinformatics — Posted on 2021-10-16
1995 Mapping enzyme catalysis with metabolomic biosensing
Xu, L.; Chang, K.-C.; Payne, E. M.; Modavi, C.; Liu, L.; Palmer, C.; Tao, N.; Alper, H. S.; Kennedy, R. T.; Cornett, D. S.; Abate, A. R.
10.1101/2021.10.15.464597 — bioengineering — Posted on 2021-10-16
1997 In vivo adenine base editing corrects newborn murine model of Hurler syndrome
Su, J.; Jing, X.; She, K. q.; Zhong, X. m.; Zhao, Q. y.; Xiao, J. l.; Li, R. t.; Deng, H. x.; Yang, Y.
10.1101/2021.10.16.464213 — genetics — Posted on 2021-10-16
1999 Evolutionary epidemiology of a zoonosis
Corsi, G. I.; Tichkule, S.; Sannella, A. R.; Vatta, P.; Asnicar, F.; Segata, N.; Jex, A. R.; Oosterhout, C. v.; Caccio, S. M.
10.1101/2021.10.15.464618 — evolutionary biology — Posted on 2021-10-16
2000 Estimating the maximal growth rates of eukaryotic microbes from cultures and metagenomes via codon usage patterns
Weissman, J. L.; Dimbo, E.-R. O.; Krinos, A. I.; Neely, C.; Yagues, Y.; Nolin, D.; Hou, S.; Laperriere, S.; Caron, D. A.; Tully, B. L.; Alexander, H.; Fuhrman, J. A.
10.1101/2021.10.15.464604 — microbiology — Posted on 2021-10-16
2001 Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and enhance protection of anti-CSP monoclonal antibodies
Wilder, B. K.; Vigdorovich, V.; Carbonetti, S.; Minkah, N.; Hertoghs, N.; Raappana, A.; Cardamone, H.; Oliver, B. G.; Trakhimets, O.; Kumar, S.; Dambrauskas, N.; Arredondo, S. A.; Camargo, N.; Kappe, S. H. I.; Sather, D. N.
10.1101/2021.10.15.464611 — microbiology — Posted on 2021-10-16
2002 The Respiratory Resistance Sensitivity Task: An Automated Method for Quantifying Respiratory Interoception and Metacognition
Nikolova, N.; Harrison, O. K.; Toohey, S.; Braendholt, M.; Legrand, N.; Correa, C. C.; Vejlo, M.; Fardo, F.; Allen, M.
10.1101/2021.10.14.464418 — neuroscience — Posted on 2021-10-16
2004 Bilaterally Reduced Rolandic Beta Band Activity in Minor Stroke Patients
Kulasingham, J. P.; Brodbeck, C.; Khan, S.; Marsh, E. B.; Simon, J. Z.
10.1101/2021.10.15.464457 — neuroscience — Posted on 2021-10-16
2009 Cortical Spheroid Model for Studying the Effects of Ischemic Brain Injury
McLaughlin, R. M.; Laguna, A.; Top, I.; Hernadez, C.; Livi, L. L.; Kramer, L.; Zambuto, S.; Hoffman-Kim, D.
10.1101/2021.10.16.464587 — neuroscience — Posted on 2021-10-16
2010 Association of ocean macroplastic debris with stranded sea turtles in the Central Gulf of Thailand
Prampramote, J.; Boonhoh, W.; Intongead, S.; Sakornwimol, W.; Prachamkhai, P.; Sansamur, C.; Hayakijkosol, O.; Wongtawan, T.
10.1101/2021.10.15.464521 — zoology — Posted on 2021-10-16
2011 Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment
Thapa, D.; Xie, B.; Mushala, B. A.; Zhang, M.; Manning, J. R.; Bugga, P.; Stoner, M. W.; Jurczak, M. J.; Scott, I.
10.1101/2021.10.15.464576 — physiology — Posted on 2021-10-16
2016 Using a Homeogram to Detect Sleep in Free-living Animals
Gaidica, M.; Studd, E.; Wishart, A. E.; Gonzalez, W.; Lane, J.; McAdam, A. G.; Boutin, S.; Dantzer, B.
10.1101/2021.10.14.464397 — animal behavior and cognition — Posted on 2021-10-16
2019 Admixture dynamics in colonial Mexico and the genetic legacy of the Manila Galleon
Rodriguez-Rodriguez, J. E.; Ioannidis, A. G.; Landa-Chavarria, E.; Blanco-Portillo, J.; Quinto-Cortes, C. D.; Penaloza-Espinosa, R. I.; Sandoval, K.; Moreno-Estrada, A.
10.1101/2021.10.09.463780 — genetics — Posted on 2021-10-16
2020 Into the range: a latitudinal gradient or a center-margins differentiation of ecological strategies in Arabidopsis thaliana?
Estarague, A.; Vasseur, F.; Sartori, K.; Bastias, C.; Cornet, D.; Rouan, L.; Beurier, G.; Exposito-Alonso, M.; Herbette, S.; Bresson, J.; Vile, D.; Violle, C.
10.1101/2021.10.15.461205 — ecology — Posted on 2021-10-16
2022 Intrinsic maturation of sleep output neurons regulates sleep ontogeny in Drosophila
Gong, N. N.; Dang, A. H.; Mainwaring, B.; Shields, E.; Schmeckpeper, K.; Bonasio, R.; Kayser, M. S.
10.1101/2021.10.14.464413 — neuroscience — Posted on 2021-10-16
2023 Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimers Disease
Ju, Y. H.; Bhalla, M.; Hyeon, S. J.; Oh, J. E.; Yoo, S.; Chae, U.; Kwon, J.; Koh, W.; Lim, J.; Park, Y. M.; Lee, J.; Cho, I. J.; Lee, H.; Ryu, H.; Lee, C. J. J.
10.1101/2021.10.15.464517 — neuroscience — Posted on 2021-10-16
2024 Tiam1-mediated synaptic plasticity drives comorbid depressive symptoms in chronic pain
Ru, Q.; Lu, Y.; Saifullah, A. B.; Blanco, F. A.; Yao, C.; Cata, J. P.; Li, D.-P.; Tolias, K. F.; Li, L.
10.1101/2021.10.15.464592 — neuroscience — Posted on 2021-10-16
2025 Single-cell Networks Reorganise to Facilitate Whole-brain Supercritical Dynamics During Epileptic Seizures
Burrows, D. R.; Diana, G.; Pimpel, B.; Moeller, F.; Richardson, M. P.; Bassett, D. S.; Meyer, M. P.; Rosch, R. E.
10.1101/2021.10.14.464473 — neuroscience — Posted on 2021-10-16
2028 Enhanced mismatch negativity responses in harmonic compared to inharmonic sound sequences
Quiroga-Martinez, D. R.; Basinski, K.; Nasielski, J.; Tillmann, B.; Brattico, E.; Cholvy, F.; Fornoni, L.; Vuust, P.; Caclin, A.
10.1101/2021.10.15.464562 — neuroscience — Posted on 2021-10-16
2029 Brain functional connectome defines a transdiagnostic dimension associated with cognition and psychopathology in youth
Xiao, X.; Hammond, C. J.; Salmeron, B. J.; Gu, H.; Zhai, T.; Nguyen, H.; Lu, H.; Ross, T. J.; Yang, Y.
10.1101/2021.10.14.464403 — neuroscience — Posted on 2021-10-16
2033 Alpha cell dysfunction in early type 1 diabetes
Doliba, N.; Rozo, A.; Roman, J.; Qin, W.; Traum, D.; Gao, L.; Liu, J.; Manduchi, E.; Liu, C.; Golson, M.; Vahedi, G.; Naji, A.; Matschinsky, F.; Atkinson, M.; Powers, A.; Brissova, M.; Kaestner, K. H.; Stoffers, D.
10.1101/2021.10.15.464545 — physiology — Posted on 2021-10-16
2037 PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery
Koc, S.; Lloyd, M. W.; Grover, J.; Seepo, S.; Lakshmi Subramanian, S.; Ray, M.; Frech, C.; DiGiovanna, J.; Webster, P.; Neuhauser, S.; Srivastava, A.; Yi Woo, X.; Sanderson, B. J.; White, B.; Lott, P.; PDXNet Consortium, ; Evard, Y. A.; Wallace, T. A.; Moscow, J. A.; Doroshow, J. H.; Mitsuades, N.; Kaochar, S.; Pan, C.-x.; Chen, M. S.; Carvajal-Carmona, L.; Welm, A. L.; Welm, B. E.; Lewis, M. T.; Ramaswarmy, G.; Ding, L.; Li, S.; Herlyn, M.; Davies, M.; Roth, J.; Meric-Bernstam, F.; Robinson, P. N.; Bult, C. J.; Davis-Dusenbery, B.; Dean, D. A.; Chuang, J. H.
10.1101/2021.10.15.464537 — cancer biology — Posted on 2021-10-16
2038 The Pathogenic R5L Mutation Disrupts Formation of Tau Complexes on the Microtubule by Altering Local N-Terminal Structure
Cario, A.; Savastano, A.; Wood, N. B.; Liu, Z.; Previs, M. J.; Hendricks, A. G.; Zweckstetter, M.; Berger, C. L.
10.1101/2021.10.15.464588 — biophysics — Posted on 2021-10-16
2043 SURFMAP: a software for mapping in two dimensions protein surface features
Schweke, H.; Mucchielli, M.-H.; Chevrollier, N.; Gosset, S.; Lopes, A.
10.1101/2021.10.15.464543 — bioinformatics — Posted on 2021-10-16
2048 Effects of early and late life environments on ageing
Sanghvi, K.; Iglesias-Carrasco, M.; Zajitscheck, F.; Kruuk, L.; Head, M.
10.1101/2021.10.15.464502 — evolutionary biology — Posted on 2021-10-16
2051 Synchronous seasonality in the gut microbiota of wild wood mouse populations
Marsh, K. J.; Raulo, A. M.; Brouard, M.; Troitsky, T.; English, H. M.; Allen, B.; Raval, R.; Webster, J. P.; Knowles, S. C. L.
10.1101/2021.10.15.464528 — ecology — Posted on 2021-10-16
2053 Accounting for animal movement improves vaccination strategies against wildlife disease in heterogeneous landscapes
McClure, K. M.; Bastille-Rousseau, G.; Davis, A. J.; Stengel, C. A.; Nelson, K.; Wittemyer, G.; Abdo, Z.; Gilbert, A. T.; Pepin, K. M.
10.1101/2021.10.15.464547 — ecology — Posted on 2021-10-16
2054 The biological sink of atmospheric H2 is more sensitive to spatial variation of microbial diversity than N2O and CO2 emissions in an agroecosystem
Baril, X.; Durand, A.-A.; Srei, N.; Lamothe, S.; Provost, C.; Martineau, C.; Guertin, C.; Dunfield, K. E.; Constant, P.
10.1101/2021.10.15.464264 — ecology — Posted on 2021-10-16
2055 Separating neural oscillations from aperiodic 1/f activity: challenges and recommendations
Gerster, M.; Waterstraat, G.; Litvak, V.; Lehnertz, K.; Schnitzler, A.; Florin, E.; Curio, G.; Nikulin, V.
10.1101/2021.10.15.464483 — neuroscience — Posted on 2021-10-16
2056 Decoding of cortex-wide brain activity from local recordings of neural potentials
Liu, X.; Ren, C.; Huang, Z.; Wilson, M.; Kim, J.-H.; Lu, Y.; Ramezani, M.; Komiyama, T.; Kuzum, D.
10.1101/2021.10.14.464468 — neuroscience — Posted on 2021-10-16
2057 Dysfunctional temporal stages of eye-gaze perception in adults with ADHD: a high-density EEG study
Mauriello, C.; Pham, E.; Kumar, S.; Piguet, C.; Aubry, J.-M.; Dayer, A.; Michel, C.; Perroud, N.; Berchio, C.
10.1101/2021.10.14.464365 — neuroscience — Posted on 2021-10-16
2058 Unifying turbulent dynamics framework distinguishes different brain states
Escrichs, A.; Sanz, Y.; Uribe, C.; Camara, E.; Türker, B.; Pyatigorskaya, N.; Lopez-Gonzalez, A.; Pallavicini, C.; Panda, R.; Annen, J.; Gosseries, O.; Laureys, S.; Naccache, L.; Sitt, J.; Laufs, H.; Tagliazucchi, E.; Kringelbach, M. L.; Deco, G.
10.1101/2021.10.14.464380 — neuroscience — Posted on 2021-10-16
2059 Spatial signatures of anesthesia-induced burst-suppression differ between primates and rodents
Sirmpilatze, N.; Mylius, J.; Ortiz-Rios, M.; Baudewig, J.; Paasonen, J.; Golkowski, D.; Ranft, A.; Ilg, R.; Gröhn, O.; Boretius, S.
10.1101/2021.10.15.464515 — neuroscience — Posted on 2021-10-16
2064 Stimulus-dependent orientation strategies in monarch butterflies
Franzke, M.; Kraus, C.; Gayler, M.; Dreyer, D.; Pfeiffer, K.; el Jundi, B.
10.1101/2021.10.14.464409 — animal behavior and cognition — Posted on 2021-10-16
2068 Evidence that faecal carriage of resistant Escherichia coli by 16-week-old dogs in the United Kingdom is associated with raw feeding
Mounsey, O.; Wareham, K.; Hammond, A.; Findlay, J.; Gould, V. C.; Morley, K.; Cogan, T. A.; Turner, K. M.; Avison, M. B.; Reyher, K. K.
10.1101/2021.04.17.440283 — microbiology — Posted on 2021-10-16
2069 Default and Control networks connectivity dynamics track the stream of affect at multiple timescales
Lettieri, G.; Handjaras, G.; Setti, F.; Cappello, E. M.; Bruno, V.; Diano, M.; Leo, A.; Ricciardi, E.; Pietrini, P.; Cecchetti, L.
10.1101/2020.06.06.137851 — neuroscience — Posted on 2021-10-16
2070 Fetal programming by sodium saccharin and damage on male offspring reproductive
Godoi, A. R.; Fioravante, V. C.; Santos, B. M.; Martinez, F. E.; Pinheiro, P. F. F.
10.1101/2021.10.15.464538 — developmental biology — Posted on 2021-10-16
2071 Identifying tumor cells at the single cell level
Dohmen, J.; Baranovskii, A.; Uyar, B.; Ronen, J.; Franke, V.; Akalin, A.
10.1101/2021.10.15.463909 — cancer biology — Posted on 2021-10-16
2072 Turning high-throughput structural biology into predictive inhibitor design
Saar, K. L.; Fearon, D.; COVID Moonshot Consortium, ; von Delft, F.; Chodera, J. D.; Lee, A. A.
10.1101/2021.10.15.464568 — biophysics — Posted on 2021-10-15
2074 Single-Shot Optical Projection tomography for high-speed volumetric imaging
Darling, C. J.; Davis, S. P. X.; Kumar, S.; French, P. M. W.; McGinty, J. A.
10.1101/2021.10.15.464407 — biophysics — Posted on 2021-10-16
2076 Single cell profiling of the Timp gene family
Peeney, D.; Fan, Y.; Gurung, S.; Lazaroff, C.; Ratnayake, S.; Meerzaman, D.; Stetler-Stevenson, W. G.
10.1101/2021.10.15.464572 — cell biology — Posted on 2021-10-16
2078 Targeted Tshz3 deletion in corticostriatal circuit components segregates core autistic behaviors
Caubit, X.; Gubellini, P.; Roubertoux, P. L.; Carlier, M.; Molitor, J.; Chabbert, D.; Metwaly, M.; Salin, P.; Fatmi, A.; Belaidouni, Y.; Brosse, L.; Kerkerian-Le-Goff, L.; FASANO, L.
10.1101/2021.10.15.464549 — neuroscience — Posted on 2021-10-15
2079 Reward timing matters in motor learning
Vassiliadis, P.; Lete, A.; Duque, J.; Derosiere, G.
10.1101/2021.10.15.464563 — neuroscience — Posted on 2021-10-15
2081 Sucrose promotes D53 accumulation and tillering in rice
Patil, S. B.; Barbier, F. F.; Zhao, J.; Zafar, S. A.; Uzair, M.; Sun, Y.; Fang, J.; Bertheloot, J.; Sakr, S.; Fichtner, F.; Chabikwa, T. G.; Yuan, S.; Beveridge, C. A. A.; Li, X.
10.1101/2020.11.10.377549 — plant biology — Posted on 2021-10-15
2083 Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy
Minenkova, O.; Santapaola, D.; Milazzo, F. M.; Anastasi, A. M.; Battistuzzi, G.; Chiapparino, C.; Rosi, A.; Gritti, G.; Borleri, G.; Rambaldi, A.; Dental, C.; Viollet, C.; Pagano, B.; Salvini, L.; Marra, E.; Luberto, L.; Rossi, A.; Riccio, A.; Merlo Pich, E.; Santoro, M. G.; De Santis, R.
10.1101/2021.06.04.447066 — bioengineering — Posted on 2021-10-15
2084 Open-Source Low-Cost Cardiac Optical Mapping System
Rybashlykov, D.; Brennan, J.; Lin, Z.; Efimov, I. R.; Syunyaev, R.
10.1101/2021.10.15.464535 — bioengineering — Posted on 2021-10-15
2085 Kronos scRT: a uniform framework for single-cell replication timing analysis
Gnan, S.; Josephides, J. M.; Wu, X.; Spagnuolo, M.; Saulebekova, D.; Bohec, M.; Dumont, M.; Baudrin, L. G.; Fachinetti, D.; Baulande, S.; Chen, C.-L.
10.1101/2021.09.01.458599 — genomics — Posted on 2021-10-15
2087 Food or physics: plankton communities structured across Gulf of Alaska eddies
Kroeger, C.; Gentemann, C.; Garcia-Reyes, M.; Batten, S.; Sydeman, W.
10.1101/2021.10.15.464534 — ecology — Posted on 2021-10-15
2089 Neuronal Activation of the Gastrointestinal Tract Shapes the Gut Environment in Mice
Yoo, B. B.; Griffiths, J. A.; Thuy-Boun, P.; Cantu, V.; Weldon, K.; Challis, C.; Sweredoski, M. J.; Chan, K. Y.; Thron, T. M.; Sharon, G.; Moradian, A.; Humphrey, G.; Zhu, Q.; Shaffer, J.; Wolan, D. W.; Dorrestein, P.; Knight, R.; Gradinaru, V.; Mazmanian, S.
10.1101/2021.04.12.439539 — physiology — Posted on 2021-10-15
2090 A New Mouse Model of Diffuse Midline Glioma to Test Targeted Immunotherapies
Seblani, M. D.; Zannikou, M.; Duffy, J.; Levine, R. N.; Liu, Q.; Horbinski, C. M.; Becher, O.; Balyasnikova, I.
10.1101/2021.10.15.464284 — cancer biology — Posted on 2021-10-15
2096 Modeling microRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
Marmol-Sanchez, E.; Cirera, S.; Zingaretti, L.; Jacobsen, M. J.; Ramayo-Caldas, Y.; Jorgensen, C. B.; Fredholm, M.; Cardoso, T. F.; Quintanilla, R.; Amills, M.
10.1101/2021.07.14.452370 — genomics — Posted on 2021-10-15
2098 rbioacc: an R-package to analyse toxicokinetic data
Ratier, A.; Baudrot, V.; Kaag, M.; Siberchicot, A.; Lopes, C.; CHARLES, S.
10.1101/2021.09.08.459421 — ecology — Posted on 2021-10-15
2100 Induction of cross-reactive antibody responses against the RBD domain of the spike protein of SARS-CoV-2 by commensal microbiota
Ninnemann, J.; Budzinski, L.; Bondareva, M.; Witkowski, M.; Angermair, S.; Kreye, J.; Durek, P.; Reincke, M.; Sanchez-Sendin, E.; Yilmaz, S.; Sempert, T.; Heinz, G. A.; Tizian, C.; Raftery, M.; Schoenrich, G.; Matyushkina, D.; Smirnov, I.; Govorun, V.; Schrezenmeier, E. V.; Doerner, T.; Zocche, S.; Viviano, E.; Sehmsdorf, K. J.; Chang, H.-D.; Enghard, P.; Treskatsch, S.; Radbruch, A.; Diefenbach, A.; Pruess, H.; Mashreghi, M.-F.; Kruglov, A.
10.1101/2021.08.08.455272 — microbiology — Posted on 2021-10-15
2103 A practical PPE decontamination method using warm air and ambient humidity
Kwiek, J. J.; Pickett, C. R.; Flanigan, C. A.; Lee, M. V.; Saif, L. J.; Jahnes, J.; Blonder, G.
10.1101/2020.11.12.380196 — microbiology — Posted on 2021-10-15
2104 Protection of Hamsters Challenged with SARS-CoV-2 Variants of Concern by Two Doses of MVC-COV1901 Vaccine Followed by a Single Dose of Beta Variant Version of MVC-COV1901
Kuo, T.-Y.; Lien, C.-E.; Lin, Y.-J.; Lin, M.-Y.; Wu, C.-C.; Tang, W.-H.; Campbell, J. D.; Traquina, P.; Chuang, Y.-S.; Liu, L. T. C.; Chen, C.
10.1101/2021.09.29.462344 — immunology — Posted on 2021-10-15
2108 Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells
Tanti, A.; Belliveau, C.; Nagy, C.; Maitra, M.; Denux, F.; Perlman, K.; Chen, F.; Mpai, R.; Canonne, C.; Theberge, S.; McFarquhar, A.; Davoli, M. A.; Belzung, C.; Turecki, G.; Mechawar, N.
10.1101/2020.10.19.345355 — neuroscience — Posted on 2021-10-15
2117 Human 5p-tailed Mirtrons are Processed by RNaseP
Zia, M. F.; Peter, J.; Hoover, J.; Chen, k.-h. E.; Flynt, A. S.
10.1101/2021.10.15.464553 — molecular biology — Posted on 2021-10-15
2118 Human enteric viruses shape disease phenotype through divergent innate immunomodulation
Jeffrey, K. L.; Adiliaghdam, F.; Amatullah, H.; Digumarthi, S.; Saunders, T. L.; Rahman, R.-U.; Wong, L. P.; Sadreyev, R.; Droit, L.; Paquette, J.; Goyette, P.; Rioux, J.; Hodin, R.; Mihindukulasuriya, K.; Handley, S. A.
10.1101/2021.10.14.464404 — immunology — Posted on 2021-10-15
2119 Minimal required exposures reveal the primacy of awareness in human face perception
Lanfranco, R. C.; Canales-Johnson, A.; Rabagliati, H.; Cleeremans, A.; Carmel, D.
10.1101/2021.10.06.462913 — neuroscience — Posted on 2021-10-15
2124 Interferon-Gamma Signaling Promotes Melanoma Progression and Metastasis
Zhou, B.; Basu, J. M.; Kazmi, H. R.; Mo, X.; Preston-Alp, S.; Cai, K. Q.; Kappes, D.; Zaidi, M. R.
10.1101/2021.10.14.464463 — cancer biology — Posted on 2021-10-15
2125 KRAS is vulnerable to reversible switch-II pocket engagement in cells
Vasta, J. D.; Peacock, D. M.; Zheng, Q.; Walker, J. A.; Zhang, Z.; Zimprich, C. A.; Thomas, M. R.; Beck, M. T.; Binkowski, B. F.; Corona, C. R.; Robers, M. B.; Shokat, K. M.
10.1101/2021.10.15.464544 — cancer biology — Posted on 2021-10-15
2129 Speed fluctuations of bacterial replisomes
Bhat, D.; Hauf, S.; Plessy, C.; Yokobayashi, Y.; Pigolotti, S.
10.1101/2021.10.15.464478 — biophysics — Posted on 2021-10-15
2131 Diversity and evolution of nitric oxide reduction
Hemp, J.; Murali, R.; Pace, L. A.; Sanford, R. A.; Hatzenpichler, R.; Ward, L.; Lingappa, U.; Fischer, W. W.; Gennis, R. B.
10.1101/2021.10.15.464467 — biochemistry — Posted on 2021-10-15
2132 A phylogeny-based metric for estimating changes in transmissibility from recurrent mutations in SARS-CoV-2
Richard, D.; Shaw, L. P.; Lanfear, R.; Corbett-Detig, R.; Turakhia, Y.; Hinrichs, A. S.; McBroome, J.; Acman, M.; Owen, C.; Tan, C. C. S.; van Dorp, L.; Balloux, F.
10.1101/2021.05.06.442903 — genomics — Posted on 2021-10-15
2133 Genetic and environmental influences on the evolution of virulence in the HIV-associated opportunistic human fungal pathogen Cryptococcus neoformans
Yu, Y.; Wang, Y.; Li, L.; Chen, X.; Huang, X.; Liang, H.; Jiang, T.; Liao, G.; Chen, M.; Liping, Z.; Li, M.; Tao, Z.; Qinyu, T.; Zhao, J.; Chen, C.
10.1101/2021.10.15.464490 — genetics — Posted on 2021-10-15
2136 Golgi structural defect impairs glycosaminoglycan synthesis, sulfation, and secretion
Ahat, E.; Song, Y.; Xia, K.; Reid, W.; Li, J.; Bui, S.; Zhang, F.; Linhardt, R. J.; Wang, Y.
10.1101/2021.10.14.464461 — cell biology — Posted on 2021-10-15
2137 Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
Lu, S.; Hu, J.; Arogundade, O. A.; Goginashvili, A.; Vazquez-Sanchez, S.; Diedrich, J. K.; Gu, J.; Blum, J.; Oung, S.; Yu, H.; Ravits, J.; Liu, C.; Yates, J. R.; Cleveland, D. W.
10.1101/2021.10.14.464447 — cell biology — Posted on 2021-10-15
2138 Human - murine concordance of molecular signatures in nerve-sparing murine partial bladder outlet obstruction (NeMO)
Aitken, K. J.; Sidler, M.; Ahmed, A.; Jiang, J.-X.; Koshkebaghi, d.; Yadav, P.; Huang, R.; Delgado-Olguin, P.; Weksberg, R.; Bagli, D. J.
10.1101/2021.09.15.460523 — molecular biology — Posted on 2021-10-15
2143 Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2021-10-15
2144 Bacterial, phytoplankton, and viral dynamics of meromictic Lake Cadagno offer insights into the Proterozoic ocean microbial loop
Saini, J. S.; Hassler, C.; Cable, R. N.; Fourquez, M.; Danza, F.; Roman, S.; Tonolla, M.; Storelli, N.; Jacquet, S.; Zdobnov, E. M.; Duhaime, M. B.
10.1101/2021.10.13.464336 — microbiology — Posted on 2021-10-15
2145 Annulment of antagonism shifts properties that are beneficial to plants in two-member consortia of Bacillus velezensis
Shao, J.; Liu, Y.; Xie, J.; Stefanic, P.; Lv, Y.; Fan, B.; Mandic-Mulec, I.; Zhang, R.; Xu, Z.; Shen, Q.
10.1101/2021.10.13.464333 — microbiology — Posted on 2021-10-15
2150 Mutual Regulation between PFKP and VEGF Promotes Glioblastoma Tumor Growth
Lee, J.-H.; Lim, J. S.; Shi, Y.; Jeon, S. M.; Park, S. H.; Zhang, C.; Park, Y.-Y.; Liu, R.; Li, J.; Cho, W.-S.; Du, L.
10.1101/2021.10.14.464342 — cancer biology — Posted on 2021-10-15
2151 Dysregulated Protein Translation Control in Hidradenitis Suppurativa: Implication for Lesion-associated Squamous Cell Carcinoma Development
Jin, L.; Kashyap, M. P.; Chen, Y.; Guo, Y.; Khan, J.; Chen, J. Q.; Lee, M. B.; Oak, A.; Sinha, R.; Mukhtar, M. S.; Deshane, J. S.; Raman, C.; Elmets, C. A.; Athar, M.
10.1101/2021.10.14.464300 — cancer biology — Posted on 2021-10-15
2152 Shared and distinct genetic features in human and canine B-cell lymphomas
Coyle, K. M.; Hillman, T.; Cheung, M.; Grande, B.; Bushell, K.; Arthur, S. E.; Alcaide, M.; Thomas, N.; Dreval, K.; Wong, S.; Campbell, K.; Morin, R. D.
10.1101/2021.10.14.464277 — cancer biology — Posted on 2021-10-15
2155 In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles
Su, F.-Y.; Zhao, Q.; Dahotre, S. N.; Gamboa, L.; Bawage, S. S.; Silva Trenkle, A. D.; Zamat, A.; Phuengkham, H.; Ahmed, R.; Santangelo, P.; Kwong, G. A.
10.1101/2021.10.14.464373 — bioengineering — Posted on 2021-10-15
2157 scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation
Raine, A.; Lundmark, A.; Annett, A.; Wiman, A.-C.; Cavalli, M.; Wadelius, C.; Bergin, C.; Nordlund, J.
10.1101/2021.10.14.464375 — genomics — Posted on 2021-10-15
2158 Coral niche construction: coral recruitment increases along a coral-built structural complexity gradient
Brambilla, V.; Baird, A.; Barbosa, M.; Dehnert, I.; Madin, J. S.; Peddie, C.; Dornelas, M.
10.1101/2021.10.14.464352 — ecology — Posted on 2021-10-15
2160 Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic Mice
Zheng, X.; Higdon, L.; Gaudet, A.; Shah, M.; Balistieri, A.; Li, C.; Nadai, P.; Palaniappan, L.; Yang, X.; Santo, B.; Ginley, B.; Wang, X.; Myakala, K.; Nallagatla, P.; Levi, M.; Sarder, P.; Rosenberg, A.; Maltzman, J.; Caires, N.; Bhalla, V.
10.1101/2021.10.14.464296 — immunology — Posted on 2021-10-15
2161 Short-term plasticity in the visual thalamus
Kurzawski, J. W.; Lunghi, C.; Biagi, L.; Tosetti, M.; Morrone, M. C.; Binda, P.
10.1101/2021.10.14.464354 — neuroscience — Posted on 2021-10-15
2163 KLC4 shapes axon arbors during development and mediates adult behavior
Haynes, E. M.; He, J.; Jean-Pierre, M.; Jarzyna, M.; Eliceiri, K. W.; Huisken, J.; Halloran, M.
10.1101/2021.09.26.461872 — neuroscience — Posted on 2021-10-15
2166 Sex Differences in Cortical Morphometry during Ageing: Examining the Interplay between Lifestyle and Reproductive Factors
Costantino, M.; Bussy, A.; Pigeau, G.; Blostein, N.; Devenyi, G. A.; Markello, R. D.; Patel, R.; Gervais, N.; Chakravarty, M. M.
10.1101/2021.10.14.464259 — neuroscience — Posted on 2021-10-15
2167 Glucose uptake in mammalian cells measured by ICP-MS
Norman, N.; Ghali, J.; Radzyukevich, T.; Heiny, J.; Landero, J.
10.1101/2021.10.14.454503 — systems biology — Posted on 2021-10-15
2169 Integrating Subclonal Response Heterogeneity to Define Cancer Organoid Therapeutic Sensitivity
Kratz, J. D.; Rehman, S.; Johnson, K. A.; Gillette, A. A.; Sunil, A.; Favreau, P. F.; Pasch, C. A.; Miller, D.; Zarling, L. C.; Yeung, A. H.; Clipson, L.; Anderson, S. J.; DeZeeuw, A. K.; Sprackling, C. M.; Lemmon, K. K.; Abbott, D. E.; Burkard, M. E.; Bassetti, M. F.; Eickhoff, J. C.; Foley, E. F.; Heise, C. P.; Kimple, R. J.; Lawson, E. H.; LoConte, N. K.; Lubner, S. J.; Mulkerin, D. K.; Matkowskyj, K. A.; Sanger, C. B.; Uboha, N. V.; Mcilwain, S. J.; Ong, I. M.; Carchman, E. H.; Skala, M. C.; Deming, D. A.
10.1101/2021.10.15.464556 — cancer biology — Posted on 2021-10-15
2170 γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects
de Vries, N. L.; Haar, J. v. d.; Veninga, V.; Chalabi, M.; Ijsselsteijn, M. E.; Ploeg, M. v. d.; Bulk, J. v. d.; Ruano, D.; Haanen, J. B.; Schumacher, T. N.; Wessels, L. F. A.; Koning, F.; de Miranda, N. F. C. C.; Voest, E. E.
10.1101/2021.10.14.464229 — cancer biology — Posted on 2021-10-15
2171 MspA Porin as a Local Nanopore Probe for Membrane-bound Proteins
Hoogerheide, D. P.; Gurnev, P. A.; Gundlach, J.; Laszlo, A.; Rostovtseva, T. K.; Bezrukov, S. M.
10.1101/2021.10.15.464579 — biophysics — Posted on 2021-10-15
2172 The chromatin regulator HMGA1a undergoes phase separation in the nucleus
Zhu, H.; Narita, M.; Joseph, J. A.; Krainer, G.; Arter, W. E.; Saar, K. L.; Ermann, N.; Espinosa, J. R.; Shen, Y.; Kuri, M. A.; Qi, R.; Xu, Y.; Collepardo-Guevara, R.; Narita, M.; Knowles, T.
10.1101/2021.10.14.464384 — biophysics — Posted on 2021-10-15
2173 Labkit: Labeling and Segmentation Toolkit for Big Image Data
Arzt, M.; Deschamps, J.; Schmied, C.; Pietzsch, T.; Schmidt, D.; Haase, R.; Jug, F.
10.1101/2021.10.14.464362 — bioinformatics — Posted on 2021-10-15
2176 The 4D Nucleome Data Portal: a resource for searching and visualizing curated nucleomics data
Reiff, S. B.; Schroeder, A. J.; Kirli, K.; Cosolo, A.; Bakker, C.; Mercado, L.; Lee, S. B.; Veit, A. D.; Balashov, A. K.; Vitzthum, C.; Ronchetti, W.; Pitman, K. M.; Johnson, J.; Ehmsen, S. R.; Kerpedjiev, P.; Abdennur, N. A.; Imakaev, M.; Ozturk, S. U.; Camoglu, U.; Mirny, L.; Gehlenborg, N.; Alver, B. H.; Park, P. J.
10.1101/2021.10.14.464435 — genomics — Posted on 2021-10-15
2179 Functional screen of Inflammatory Bowel Disease genes reveals key epithelial functions
Ntunzwenimana, J. C.; Boucher, G.; Paquette, J.; Gosselin, H.; Alikashani, A.; Morin, N.; Beauchamp, C.; Thauvette, L.; Rivard, M.-E.; Dupuis, F.; Deschenes, S.; Foisy, S.; Latour, F.; Lavallee, G.; Daly, M.; Xavier, R.; the iGenoMed Consortium, ; Charron, G.; Goyette, P.; Rioux, J. D.
10.1101/2021.10.15.464566 — genetics — Posted on 2021-10-15
2180 Quantifying the scale of genetic diversity extinction in the Anthropocene
Exposito-Alonso, M.; Booker, T. A.; Czech, L.; Fukami, T.; Gillespie, L.; Hateley, S.; Kyriazis, C. C.; Lang, P.; Leventhal, L.; Nogues-Bravo, D.; Pagowski, V.; Ruffley, M.; Spence, J. P.; Toro Arana, S.; Weiss, C.; Zess, E.
10.1101/2021.10.13.464000 — ecology — Posted on 2021-10-15
2181 Oxalic acid binds to gustatory receptor Gr23a and inhibits feeding in the brown planthopper
Kang, K.; Zhang, M.; Yue, L.; Chen, W.; Dai, Y.; Lin, K.; Liu, K.; Lv, J.; Guan, Z.; Xiao, S.; Zhang, W.
10.1101/2021.10.14.464394 — ecology — Posted on 2021-10-15
2182 Lin28a rejuvenates muscle stem cells via mitochondrial optimization
Wang, P.; Liu, X.; Tan, J.-H.; Chua, M.-W.; Chua, Y.-J.; Luo, L.; Ma, S.; Cao, W.; Ma, W.; Yao, Z.; Chen, Y.; Miao, H.; Guo, L.; Zhang, L.; Guang, L.; Liang, K.; Wang, Y.; Su, J.; Liu, S.; Liu, R.; Wang, R. R.; Li, C.; Ai, N.; Li, Y.; Jiang, Z.; Liu, T.; Teh, B. T.; Jiang, L.; Yu, K.; Shyh-Chang, N.
10.1101/2021.10.14.462144 — cell biology — Posted on 2021-10-15
2185 EEG-based clusters differentiate psychological distress, sleep quality and cognitive function in adolescents
Forbes, O.; Schwenn, P. E.; Wu, P. P.-Y.; Santos-Fernandez, E.; Xie, H.-B.; Lagopoulos, J.; McLoughlin, L. T.; Sacks, D. D.; Mengersen, K.; Hermens, D. F.
10.1101/2021.10.14.464347 — neuroscience — Posted on 2021-10-15
2186 Ptbp1 deletion does not induce glia-to-neuron conversion in adult mouse retina and brain.
Hoang, T.; Kim, D. W.; Appel, H.; Pannullo, N.; Ozawa, M.; Zheng, S.; Yu, M.; Peachey, N.; Kim, J.; Blackshaw, S.
10.1101/2021.10.04.462784 — neuroscience — Posted on 2021-10-15
2187 ERα-LBD, a novel isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance
Strillacci, A.; Sansone, P.; Rajasekhar, V. R.; Turkekul, M.; Boyko, V.; Meng, F.; Houck-Loomis, B.; Brown, D.; Berger, M. F.; Hendrickson, R. C.; Chang, Q.; de Stanchina, E.; Pareja, F.; Reis-Filho, J. S.; Segu Rajappachetty, R.; Liu, B.; Penson, A.; Mastroleo, C.; Berishaj, M.; Borsetti, F.; Spisni, E.; Lyden, D.; Chandarlapaty, S.; Bromberg, J.
10.1101/2021.10.14.464262 — cancer biology — Posted on 2021-10-15
2189 Design of Specific Primer Sets for the Detection of SARS-CoV-2 Variants of Concern B.1.1.7, B.1.351, P.1, B.1.617.2 using Artificial Intelligence
Perez-Romero, C.; Tonda, A.; Mendoza-Maldonado, L.; Coz, E.; Tabeling, P.; Vanhomwegen, J.; Claassen, E.; Garssen, J.; Kraneveld, A. D.; Lopez-Rincon, A.
10.1101/2021.01.20.427043 — bioinformatics — Posted on 2021-10-15
2192 Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids
Vanslambrouck, J. M.; Wilson, S. B.; Tan, K. S.; Groenewegen, E.; Rudraraju, R.; Neil, J.; Scurr, M.; Howden, S. E.; Subbarao, K.; Little, M. H.
10.1101/2021.10.14.464320 — bioengineering — Posted on 2021-10-15
2194 Genetic map of regional sulcal morphology in the human brain
Sun, B. B.; Loomis, S. J.; Pizzagalli, F.; Shatokhina, N.; Painter, J. N.; Foley, C. N.; Biogen Biobank Team, ; Jensen, M. E.; McLaren, D. G.; Chintapalli, S. S.; Zhu, A. H.; Dixon, D.; Islam, T.; Ba Gari, I.; Runz, H.; Medland, S. E.; Thompson, P. M.; Jahanshad, N.; Whelan, C. D.
10.1101/2021.10.13.463489 — genomics — Posted on 2021-10-15
2200 The secreted neuronal signal Spock1 regulates the blood-brain barrier
O'Brown, N. M.; Patel, N. B.; Hartmann, U.; Klein, A. M.; Gu, C.; Megason, S. G.
10.1101/2021.10.13.464312 — neuroscience — Posted on 2021-10-15
2201 Motor Learning Drives Dynamic Patterns of Intermittent Myelination onBehaviorally-Activated Axons
Bacmeister, C. M.; Huang, R.; Thornton, M. A.; Conant, L.; Chavez, A. R.; Poleg-Polsky, A. G.; Hughes, E. G.
10.1101/2021.10.13.464319 — neuroscience — Posted on 2021-10-15
2203 Rilmenidine mimics caloric restriction via the nischarin I1-imidazoline receptor to extend lifespan in C. elegans
Bennett, D. F.; Goyala, A.; Statzer, C.; Beckett, C. W.; Tyshkovskiy, A.; Gladyshev, V. N.; Ewald, C. Y.; de Magalhaes, J. P.
10.1101/2021.10.13.464294 — pharmacology and toxicology — Posted on 2021-10-15
2204 Hyperconcentrated Mucus Unifies Submucosal Gland and Superficial Airway Dysfunction in Cystic Fibrosis
Kato, T.; Radicioni, G.; Papanikolas, M. J.; Stoychev, G. V.; Markovetz, M. R.; Aoki, K.; Porterfield, M.; Okuda, K.; Cardenas, S. M. B.; Gilmore, R. C.; Morrison, C. B.; Ehre, C.; Burns, K. A.; White, K. K.; Brennan, T. A.; Goodell, H. P.; Thacker, H.; Loznev, H. T.; Forsberg, L. J.; Nagase, T.; Rubinstein, M.; Randell, S. H.; Tiemeyer, M.; Hill, D. B.; Kesimer, M.; O'Neal, W. K.; Ballard, S. T.; Freeman, R.; Button, B.; Boucher, R. C.
10.1101/2021.09.22.461306 — pathology — Posted on 2021-10-15
2206 Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate
Pfeifer, C. R.; Tobin, M. P.; Cho, S.; Vashisth, M.; Dooling, L. J.; Vasquez, L. L.; Ricci-De Lucca, E. G.; Simon, K. T.; Discher, D. E.
10.1101/2021.10.13.464257 — biophysics — Posted on 2021-10-15
2208 A High-Resolution Method for the Systematic Detection of EMS-Induced Mutations in a Sequenced Population
Simons, J.; Herbert, T.; Kauffman, C.; Batete, M.; Simpson, A. T.; Katsuki, Y.; Le, D.; Amundson, D.; Buescher, E.; Weil, C.; Tuinstra, M. R.; Addo-Quaye, C.
10.1101/2021.10.13.464286 — bioinformatics — Posted on 2021-10-15
2210 A nesprin-4/kinesin-1 cargo model for nucleus positioning in cochlear outer hair cells
Taiber, S.; Gozlan, O.; Cohen, R.; Andrade, L.; Moran, Y.; Hipp, R.; Kelley, M. W.; Manor, U.; Sprinzak, D.; Avraham, K. B.
10.1101/2021.10.10.463824 — cell biology — Posted on 2021-10-15
2211 Development and Application of Multidimensional Lipid Libraries to Investigate Lipidomic Dysregulation Related to Smoke Inhalation Injury Severity
Kirkwood, K. I.; Christopher, M. W.; Burgess, J. L.; Littau, S. R.; Pratt, B. S.; Shulman, N.; Tamura, K.; MacCoss, M. J.; MacLean, B. X.; Baker, E. S.
10.1101/2021.10.13.464246 — molecular biology — Posted on 2021-10-15
2213 Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson, B. A.; Zhou, Y.; Lokugamage, K. G.; Vu, M. N.; Bopp, N. E.; Crocquet-Valdes, P. A.; Schindewolf, C.; Liu, Y.; Scharton, D.; Plante, J. A.; Xie, X.; Aguilar, P.; Weaver, S.; Shi, P.-Y.; Walker, D. H.; Routh, A. L.; Menachery, V. D.
10.1101/2021.10.14.464390 — microbiology — Posted on 2021-10-15
2214 Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis
Bahnan, W.; Wrighton, S.; Sundwall, M.; Bläckberg, A.; Larsson, O.; Höglund, U.; Khakzad, H.; Godzwon, M.; Walle, M.; Elder, E.; Happonen, L.; Andre, O.; Kumra Ahnlide, J.; Hellmark, T.; Wendel-Hansen, V.; Wallin, R. P.; Malmström, J.; Malmström, L.; Ohlin, M.; Rasmussen, M.; Nordenfelt, P.
10.1101/2021.10.14.464464 — immunology — Posted on 2021-10-15
2217 Parkinsonian gait effects with DBS are associated with pallido-peduncular axis activation
Goftari, M.; Lu, C.; Schmidt, M.; Patriat, R.; Palnitkar, T.; Kim, J.; Harel, N.; Johnson, M. D.; Cooper, S. E.
10.1101/2021.10.13.464270 — neuroscience — Posted on 2021-10-15
2218 Encoding of inflammatory hyperalgesia in mice spinal cord
Barkai, O.; Butterman, R.; Rayi, P. R.; Katz, B.; Lev, S.; Binshtok, A. M.
10.1101/2021.05.18.444665 — neuroscience — Posted on 2021-10-15
2219 Dual polarity voltage imaging reveals subthreshold dynamics and concurrent spiking patterns of multiple neuron-types
Kannan, M.; Vasan, G.; Haziza, S.; Huang, C.; Chrapkiewicz, R.; Luo, J.; Cardin, J. A.; Schnitzer, M. J.; Pieribone, V. A.
10.1101/2021.10.13.463730 — neuroscience — Posted on 2021-10-15
2220 The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female Orexin/tTA; TetO-DTA Mice
Sun, Y.; Tisdale, R.; Park, S.; Heu, J.; Ma, S.-C.; Haire, M.; Allocca, G.; Yamanaka, A.; Morairty, S. R.; Kilduff, T. S.
10.1101/2021.10.13.463880 — neuroscience — Posted on 2021-10-15
2221 Multifunctional Cre-dependent transgenic mice for high-precision all-optical interrogation of neural circuits
Bounds, H. A.; Sadahiro, M.; Hendricks, W. D.; Gajowa, M.; Oldenburg, I. A.; Gopakumar, K.; Quintana, D.; Tasic, B.; Daigle, T.; Zeng, H.; Adesnik, H.
10.1101/2021.10.05.463223 — neuroscience — Posted on 2021-10-15
2222 Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks
Dudek, M.; Pathiranage, D.; Goncalves, C. F.; Lawless, C.; Wang, D.; Luo, Z.; Yang, L.; Guilak, F.; Hoyland, J. A.; Meng, Q.-J.
10.1101/2021.10.01.462769 — physiology — Posted on 2021-10-15
2223 Radiation-reprogrammed glioma stem cells generate vascular-like cells to build a trophic niche driving tumor recurrence
Muthukrishnan, S. D.; Kawaguchi, R.; Nair, P.; Prasad, R.; Qin, Y.; Johnson, M.; Vanderveer-Harris, N.; Pham, A.; Wang, Q.; Condro, M. C.; Alvarado, A. G.; Gau, R.; Castro, M. G.; Lowenstein, P. R.; Deb, A.; Hinman, J. D.; Pajonk, F.; Burns, T. C.; Goldman, S. R.; Geschwind, D.; Kornblum, H. I.
10.1101/2021.06.03.447005 — cancer biology — Posted on 2021-10-15
2229 Palaeogenomics reveal a hybrid origin of the world's largest Camelus species
Yuan, J.; Westbury, M. V.; Chen, S.; Hu, J.; Zhang, F.; Wang, S.; Zhang, Z.; Wang, L.; Xiao, B.; Hou, X.; Li, F.; Lai, X.; Liu, W.; Sheng, G.
10.1101/2021.10.14.464381 — molecular biology — Posted on 2021-10-15
2230 Control of Parallel Hippocampal Output Pathways by Amygdalar Long-Range Inhibition
AlSubaie, R.; Wee, R. W. S.; Ritoux, A.; Mishchanchuk, K.; Passlack, J.; Regester, D.; MacAskill, A. F.
10.1101/2021.03.08.434367 — neuroscience — Posted on 2021-10-15
2232 pyControl: Open source, Python based, hardware and software for controlling behavioural neuroscience experiments.
Akam, T.; Lustig, A.; Rowland, J.; Kapanaiah, S. K. T.; Esteve-Agraz, J.; Panniello, M.; Marquez, C.; Kohl, M.; Kätzel, D.; Costa, R. M.; Walton, M. E.
10.1101/2021.02.22.432227 — neuroscience — Posted on 2021-10-15
2233 CAR modulates plasma membrane nano-organization and immune signaling downstream of RALF1-FERONIA ligand-receptor signaling system
Chen, W.; Zhou, H.; Xu, F.; Yu, M.; Coego, A.; Rodriguez, L.; Lu, Y.; Xie, Q.; Fu, Q.; Chen, J.; Li, L.; Xu, G.; Wu, D.; Li, X.; Dai, S.; Li, X.; Jaillais, Y.; Rodriguez, P. L.; Yu, F.; Zhu, S.
10.1101/2021.10.13.464316 — plant biology — Posted on 2021-10-15
2234 Acoustic regularities in infant-directed speech and song across cultures
Hilton, C. B.; Moser, C. J.; Bertolo, M.; Lee-Rubin, H.; Amir, D.; Bainbridge, C. M.; Simson, J.; Knox, D.; Glowacki, L.; Galbarczyk, A.; Jasienska, G.; Ross, C.; Neff, M. B.; Martin, A.; Cirelli, L. K.; Trehub, S. E.; Song, J.; Kim, M.; Schachner, A.; Vardy, T. A.; Atkinson, Q. D.; Antfolk, J.; Madhivanan, P.; Siddaiah, A.; Placek, C. D.; Salali, G. D.; Keestra, S.; Singh, M.; Collins, S. A.; Patton, J. Q.; Scaff, C.; Stieglitz, J.; Moya, C.; Sagar, R. R.; Wood, B. M.; Krasnow, M. M.; Mehr, S. A.
10.1101/2020.04.09.032995 — animal behavior and cognition — Posted on 2021-10-15
2236 Analysing economic costs of invasive alien species with the invacost R package
Leroy, B.; Kramer, A. M.; Vaissiere, A.-C.; Courchamp, F.; Diagne, C.
10.1101/2020.12.10.419432 — ecology — Posted on 2021-10-15
2237 EXOSC10/Rrp6 is essential for the eight-cell embryo/morula transition
Petit, F. G.; Jamin, S. P.; Kernanec, P.-Y.; Becker, E.; Halet, G.; Primig, M.
10.1101/2021.10.06.463350 — developmental biology — Posted on 2021-10-15
2238 Comprehensive-immunopeptidomics analysis reveals presentation of potential neoantigens carrying cancer driver mutations
Minegishi, Y.; Kiyotani, K.; Nemoto, K.; Inoue, Y.; Haga, Y.; Fujii, R.; Saichi, N.; Nagayama, S.; Ueda, K.
10.1101/2021.04.09.439118 — cancer biology — Posted on 2021-10-15
2240 Subsurface Hydrocarbon Degradation Strategies in Low- and High-Sulfate Coal Seam Communities Identified with Activity-Based Metagenomics
Schweitzer, H. D.; Smith, H. J.; Barnhart, E. P.; McKay, L. J.; Gerlach, R.; Cunningham, A. B.; Malmstrom, R.; Goudeau, D.; Fields, M. W.
10.1101/2021.08.26.457739 — microbiology — Posted on 2021-10-15
2241 Twisting DNA by Salt
Cruz-León, S.; Vanderlinden, W.; Müller, P.; Forster, T.; Staudt, G.; Lin, Y.-Y.; Lipfert, J.; Schwierz, N.
10.1101/2021.07.14.452306 — biophysics — Posted on 2021-10-15
2242 Learned deconvolution using physics priors for structured light-sheet microscopy
Wijesinghe, P.; Corsetti, S.; Chow, D. J. X.; Sakata, S.; Dunning, K.; Dholakia, K.
10.1101/2021.05.26.445797 — biophysics — Posted on 2021-10-15
2243 Costs dictate strategic investment in dominance interactions
Dehnen, T.; Papageorgiou, D.; Nyaguthii, B.; Cherono, W.; Penndorf, J.; Boogert, N. J.; Farine, D. R.
10.1101/2021.06.02.446695 — animal behavior and cognition — Posted on 2021-10-15
2246 Representing the sediment retention ecosystem service within an ecosystem account of the Mitchell catchment
McMahon, J. M.; Hasan, S.; Brooks, A.; Curwen, G.; Dyke, J.; Saint Ange, C.; Smart, J. C. R.
10.1101/2021.08.06.455476 — ecology — Posted on 2021-10-15
2248 COLD ATMOSPHERIC PLASMA DIFFERENTIALLY AFFECTS CELL RENEWAL AND DIFFERENTIATION OF STEM CELLS AND APC-DEFICIENT-DERIVED TUMOR CELLS IN INTESTINAL ORGANOIDS
Hadefi, A.; Leprovots, M.; Thulliez, M.; Bastin, O.; Lefort, A.; Libert, F.; Nonclercq, A.; Delchambre, A.; Reniers, F.; Deviere, J.; Garcia, M.-I.
10.1101/2021.10.13.464287 — cell biology — Posted on 2021-10-15
2249 An Arginine-Rich Motif in the ORF2 Capsid Protein Regulates the Hepatitis E Virus Lifecycle and Interactions with the Host Cell
Hervouet, K.; Ferrie, M.; Ankavay, M.; Montpellier, C.; Camuzet, C.; Alexandre, V.; Dembele, A.; Lecoeur, C.; Foe, A. T.; Bouquet, P.; Hot, D.; Vausselin, T.; Saliou, J.-M.; Salome-Desnoulez, S.; Marsollier, L.; Brodin, P.; Dreux, M.; Rouille, Y.; Dubuisson, J.; Aliouat-Denis, C.-M.; Cocquerel, L.
10.1101/2021.05.26.445820 — microbiology — Posted on 2021-10-15
2251 Central Neural Regulation of Parathyroid Hormone
Zhang, L.; Liu, N.; Shao, J.; Gao, D.; Liu, Y.; Chen, D.; Wang, L.; Lu, W. W.; Yang, F.
10.1101/2020.11.30.403279 — neuroscience — Posted on 2021-10-15
2253 Predicting speech from a cortical hierarchy of event-based timescales
Schmitt, L.-M.; Erb, J.; Tune, S.; Rysop, A.; Hartwigsen, G.; Obleser, J.
10.1101/2020.12.19.423616 — neuroscience — Posted on 2021-10-15
2256 PRMT5 in T cells drives Th17 responses, mixed granulocytic inflammation and severe allergic airway inflammation
Lewis, B. W.; Amici, S. A.; Kim, H.-Y.; Shalosky, E.; Khan, A.; Walum, J.; Gowdy, K. M.; Englert, J.; Porter, N. A.; Grayson, M. H.; Britt, R. D.; Guerau-de-Arellano, M.
10.1101/2021.10.13.464281 — immunology — Posted on 2021-10-14
2257 BBX proteins promote HY5-mediated UVR8 signaling in Arabidopsis
Podolec, R.; Wagnon, T. B.; Leonardelli, M.; Johansson, H.; Ulm, R.
10.1101/2021.10.14.464399 — plant biology — Posted on 2021-10-14
2259 ATP and Substrate Binding Regulates Conformational Changes of Human Peroxisomal ABC Transporter ALDP
xiong, c.; Jia, L.-N.; Shen, M.-H.; Xiong, W.-X.; Xiong, L.-L.; Wang, T.-H.; Zhou, D.; Liu, Z.; Tang, L.
10.1101/2021.10.14.464310 — biochemistry — Posted on 2021-10-14
2262 A Proposed Unified Mitotic Chromosome Architecture
Sedat, J.; McDonald, A.; Kasler, H. G.; Verdin, E.; Cang, H.; Arigovindan, M.; Murre, C.; Elbaum, M.
10.1101/2021.10.14.464227 — cell biology — Posted on 2021-10-14
2263 Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E
Dewees, S. I.; Vargova, R.; Hardin, K. R.; Turn, R. E.; Devi, S.; Linnert, J.; Wolfrum, U.; Caspary, T.; Elias, M.; Kahn, R.
10.1101/2021.10.14.464442 — cell biology — Posted on 2021-10-14
2268 Actin dynamics regulation by TTC7A/PI4KIIIα axis limits DNA damage and cell death during leukocyte migration
Gajardo, T.; Lo, M.; Bernard, M.; Leveau, C.; El-Daher, M.-T.; Kurowska, M.; Le Lay, G.; Moshous, D.; Neven, B.; Fischer, A.; Menasche, G.; de Saint Basile, G.; Vargas, P.; Sepulveda, F. E.
10.1101/2021.10.14.464382 — immunology — Posted on 2021-10-14
2269 THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS
Kay, A. G.; Treadwell, K.; Roach, P.; Morgan, R.; Lodge, R.; Hyland, M.; Piccinini, A.; Forsyth, N. R.; Kehoe, O.
10.1101/2021.06.28.450178 — immunology — Posted on 2021-10-14
2270 LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming
van der Zande, H. J. P.; Brombacher, E. C.; Lambooij, J. M.; Pelgrom, L. R.; Zawistowska-Deniziak, A.; Patente, T. A.; Heieis, G. A.; Otto, F.; Ozir-Fazalalikhan, A.; Yazdanbakhsh, M.; Everts, B.; Guigas, B.
10.1101/2021.10.14.464396 — immunology — Posted on 2021-10-14
2272 Conjugation-based genome engineering in Deinococcus radiodurans
Brumwell, S. L.; Van Belois, K. D.; Giguere, D. J.; Edgell, D. R.; Karas, B. J.
10.1101/2021.10.13.464295 — synthetic biology — Posted on 2021-10-14
2274 A KARRIKIN INSENSITIVE2 paralog in lettuce mediates highly sensitive germination responses to karrikinolide
Martinez, S. E.; Conn, C. E.; Guercio, A. M.; Sepulveda, C.; Fiscus, C. J.; Koenig, D.; Shabek, N.; Nelson, D. C.
10.1101/2021.10.13.464162 — plant biology — Posted on 2021-10-14
2275 Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in mice
Robarts, D. R.; McGreal, S. R.; Umbaugh, D. S.; Parkes, W. S.; Kotulkar, M.; Abernathy, S.; Lee, N.; Jaeschke, H.; Gunewardena, S.; Whelan, S. A.; Hanover, J. A.; Zachara, N. E.; Slawson, C.; Apte, U.
10.1101/2021.10.14.464401 — pathology — Posted on 2021-10-14
2277 Cross-seeding Controls Aβ Fibril Populations and Resulting Function
Pan, H. S.; Lucas, M. J.; Verbeke, E. J.; Partipilo, G. M.; Helfman, E. C.; Kann, L.; Keitz, B. K.; Taylor, D. W.; Webb, L. J.
10.1101/2021.10.14.464427 — biochemistry — Posted on 2021-10-14
2278 Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling
Zimmerman, S. M.; Fropf, R.; Kulasekara, B. R.; Griswold, M.; Appelbe, O.; Bahrami, A.; Boykin, R.; Buhr, D. L.; Fuhrman, K.; Hoang, M. L.; Huynh, Q.; Isgur, L.; Klock, A.; Kutchma, A.; Lasley, A. E.; Liang, Y.; McKay-Fleisch, J.; Nelson, J. S.; Nguyen, K.; Piazza, E.; Rininger, A.; Zollinger, D. R.; Rhodes, M.; Beechem, J. M.
10.1101/2021.09.29.462442 — genomics — Posted on 2021-10-14
2280 Local and global crosstalk among heterochromatin marks drives epigenome patterning in Arabidopsis
To, T. K.; Yamasaki, C.; Oda, S.; Tominaga, S.; Kobayashi, A.; Tarutani, Y.; Kakutani, T.
10.1101/2021.10.14.464341 — genomics — Posted on 2021-10-14
2282 A Rapid Bead-Based Assay For Screening Of SARS-CoV-2 Neutralising Antibodies
SL, S.; Darvin, P.; Chandrasekharan, A.; Varadarajan, S. N.; Divakaran, S. J.; Easwaran, S.; Nelson-Sathi, S.; Perunthottathu, U. K.; Jones, S.; Joseph, I.; Pillai, R. M.; TR, S. K.
10.1101/2021.10.13.464050 — molecular biology — Posted on 2021-10-14
2283 A Novel Mice Model of Catecholaminergic Polymorphic Ventricular Tachycardia Generated by CRISPR/Cas9
hou, c.; jiang, X.; Qiu, Q.; Zheng, J.; Lin, S.; Chen, S.; Xu, M.; Zhang, Y.; xie, l.; tingting, x.
10.1101/2021.10.14.464343 — molecular biology — Posted on 2021-10-14
2285 Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer
Jahid, S.; Ortega, J. A.; Vuong, L. M.; Acquistapace, I. M.; Hachey, S. J.; Flesher, J. L.; La Serra, M. A.; Brindani, N.; La Sala, G.; Manigrasso, J.; Arencibia, J. M.; Bertozzi, S. M.; Summa, M.; Bertorelli, R.; Armirotti, A.; Jin, R.; Liu, Z.; Chen, C.-F.; Edwards, R.; Hughes, C. C. W.; De Vivo, M.; Ganesan, A. K.
10.1101/2021.10.14.464305 — molecular biology — Posted on 2021-10-14
2287 The Endocytic Recycling Compartment Serves as a Viral Factory for Hepatitis E Virus
Bentaleb, C.; Hervouet, K.; Montpellier, C.; Camuzet, C.; Burlaud-Gaillard, J.; Ferrie, M.; Werkmeister, E.; Metzger, K.; Janampa, N. L.; Marlet, J.; Roux, J.; Deffaud, C.; Goffard, A.; Rouille, Y.; Dubuisson, J.; Roingeard, P.; Aliouat-Denis, C.-M.; Cocquerel, L.
10.1101/2021.10.14.464345 — microbiology — Posted on 2021-10-14
2289 The RAG1 Ubiquitin Ligase Domain Enhances Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity
Burn, T.; Miot, C.; Gordon, S.; Culberson, E.; Diamond, T.; Kreiger, P.; Hayer, K.; Bhattacharyya, A.; Jones, J.; Bassing, C.; Behrens, E.
10.1101/2021.01.04.425211 — immunology — Posted on 2021-10-14
2291 Distinct signatures of loss of consciousness during Focal Impaired Awareness versus Focal to Bilateral Tonic-Clonic seizures
Juan, E.; Gorska, U.; Kozma, C.; Papantonatos, C.; Bugnon, T.; Denis, C.; Kremen, V.; Worrell, G.; Struck, A.; Bateman, L.; Merricks, E. M.; Blumenfeld, H.; Tononi, G.; Schevon, C.; Boly, M.
10.1101/2021.10.01.462586 — neuroscience — Posted on 2021-10-14
2292 Enhanced nociception in a rabbit model of cerebral palsy
Reedich, E. J.; Genry, L. T.; Cavarsan, C. F.; Mena Avila, E.; Singer, M. A.; Boudreau, D. M.; Brennan, M. C.; Garrett, A. M.; Dowaliby, L.; Detloff, M. R.; Quinlan, K. A.
10.1101/2021.09.28.462176 — neuroscience — Posted on 2021-10-14
2293 Psychedelics flatten the brain's energy landscape: evidence from receptor-informed network control theory
Singleton, S. P.; Luppi, A. I.; Carhart-Harris, R. L.; Cruzat, J.; Roseman, L.; Deco, G.; Kringelbach, M. L.; Stamatakis, E. A.; Kuceyeski, A.
10.1101/2021.05.14.444193 — neuroscience — Posted on 2021-10-14
2295 ASO-based PKM Splice-switching Therapy Inhibits Hepatocellular Carcinoma Cell Growth
Ma, W. K.; Voss, D. M.; Scharner, J.; Costa, A. S. H.; Lin, K.-T.; Jeon, H. Y.; Wilkinson, J. E.; Jackson, M.; Rigo, F.; Bennett, F. C.; Krainer, A.
10.1101/2020.09.01.278580 — cancer biology — Posted on 2021-10-14
2297 Spatially Patterned Bi-electrode Epiretinal Stimulation for Axon Avoidance at Cellular Resolution
Vilkhu, R. S.; Madugula, S. S.; Grosberg, L. E.; Gogliettino, A. R.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Mitra, S.; Chichilnisky, E. J.
10.1101/2021.08.17.454395 — bioengineering — Posted on 2021-10-14
2300 Parallel evolution of phage resistance - virulence trade - offs during in vitro and nasal Pseudomonas aeruginosa phage treatment
Castledine, M.; Padfield, D.; Sierocinski, P.; Soria Pascual, J.; Hughes, A.; Mäkinen, L.; Friman, V.-P.; Pirnay, J.-P.; Merabishvili, M.; De Vos, D.; Buckling, A.
10.1101/2021.09.06.459069 — evolutionary biology — Posted on 2021-10-14
2302 Transmission of one predicts another: Apathogenic proxies for transmission dynamics of a fatal virus
Gilbertson, M. L. J.; Fountain-Jones, N. M.; Malmberg, J. L.; Gagne, R. B.; Lee, J. S.; Kraberger, S.; Kechejian, S.; Petch, R.; Chiu, E.; Onorato, D.; Cunningham, M. W.; Crooks, K. R.; Funk, W. C.; Carver, S.; VandeWoude, S.; VanderWaal, K.; Craft, M. E.
10.1101/2021.01.09.426055 — ecology — Posted on 2021-10-14
2303 Accumulation of lncRNAs/DNA hybrid reveals RNase HII transcripts down-regulation in psoriasis.
Mehmetbeyoglu, E.; Kianmehr, L.; Borlu, M.; Yilmaz, Z.; Basar Kilic, S.; Rajabi-Maham, H.; Taheri, S.; Rassoulzadegan, M.
10.1101/2021.10.12.464167 — molecular biology — Posted on 2021-10-14
2305 Chromatin remodelling by INO80 at promoter proximal pause sites promotes premature termination of mRNA synthesis
Luzzi, S.; Szachnowski, U.; Greener, S.; Schumacher, K.; Fulton, S.; Han, K. H.; Darke, J.; Piccinno, R.; Lafon, A.; Pugh, B. F.; Devys, D.; Tora, L.; Morillon, A.; Papamichos-Chronakis, M.
10.1101/2020.03.02.973685 — molecular biology — Posted on 2021-10-14
2306 Alkyne modified purines for assessing activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.
Botnar, A.; Lawrence, G.; Maher, S. P.; Vantaux, A.; Witkowski, B.; Shiau, J. C.; Merino, E. F.; De Vore, D.; Yang, C.; Murray, C.; Cassera, M. B.; Leahy, J. W.; Kyle, D. E.
10.1101/2021.10.12.464062 — microbiology — Posted on 2021-10-14
2309 Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis
Berland, C.; Castel, J.; Terrasi, R.; Montalban, E.; Foppen, E.; Martin, C.; Muccioli, G. G.; Luquet, S.; Gangarossa, G.
10.1101/2020.11.14.382291 — neuroscience — Posted on 2021-10-14
2310 Dendritic inhibition by Shh signaling-dependent stellate cell pool is critical for motor learning
Li, W.; Chen, L.; Fleming, J. T.; Brignola, E. Y.; Zavalin, K.; Lagrange, A.; Rex, T.; heiney, S. A.; Wojaczynski, G. J.; Medina, J. F.; Chiang, C.
10.1101/2021.04.15.439999 — neuroscience — Posted on 2021-10-14
2313 Debunking the "junk": Unraveling the role of lncRNA-miRNA-mRNA networks in fetal hemoglobin regulation
Rahaman, M.; Bhowmick, C.; Komanapalli, J.; Mukherjee, M.; Byram, P. K.; Shukla, P. C.; Dolai, T. K.; Chakravorty, N.
10.1101/2021.10.13.464339 — bioinformatics — Posted on 2021-10-14
2314 Protein degradation analysis by affinity microfluidics
Brio, L.; Wasserman, D.; Michaely-Barbiro, E.; Gerber, D.; Tzur, A.
10.1101/2021.10.13.464189 — bioengineering — Posted on 2021-10-14
2316 Cnidarian hair cell development illuminates an ancient role for the class IV POU transcription factor in defining mechanoreceptor identity
Ozment, E.; Tamvacakis, A. N.; Zhou, J.; Rosiles-Loeza, P. Y.; Escobar-Hernandez, E. E.; Fernandez-Valverde, S. L.; Nakanishi, N.
10.1101/2021.10.12.464036 — evolutionary biology — Posted on 2021-10-14
2319 Vaccine-induced, high magnitude HIV Env-specific antibodies with Fc-mediated effector functions are insufficient to protect infant rhesus macaques against oral SHIV infection
Curtis, A. D.; Saha, P. T.; Dennis, M.; Berendam, S. J.; Alam, S. M.; Ferrari, G.; Kozlowski, P. A.; Fouda, G. G.; Hudgens, M. G.; Van Rompay, K. K. A.; Pollara, J.; Permar, S. R.; De Paris, K.
10.1101/2021.10.11.464024 — immunology — Posted on 2021-10-14
2320 Tagging active neurons by soma-targeted Cal-Light
Hyun, J. H.; Nagahama, K.; Namkung, H.; Mignocchi, N.; Hannan, P.; Kruessel, S.; Kwak, C.; McElroy, A.; Liu, B.; Cui, M.; Lee, S.; Lee, D.; Huganir, R. L.; Sawa, A.; Kwon, H.
10.1101/2021.10.13.464095 — neuroscience — Posted on 2021-10-14
2322 SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress
Zayed, A.; Baranowski, C.; Compagnion, A. C.; Vernochet, C.; Karaki, S.; Durand de Cuttoli, R.; Saint-Jour, E.; Bhattacharya, S.; Marti, F.; Vanhoutte, P.; Yaniv, M.; Faure, P.; Barik, J.; Amar, L.; Tronche, F.; Parnaudeau, S.
10.1101/2021.10.14.464260 — neuroscience — Posted on 2021-10-14
2323 Differential and synergistic effects of low birth weight and Western diet on skeletal muscle vasculature, mitochondrial lipid metabolism and insulin signaling in male guinea pigs
Dunlop, K.; Sarr, O.; Stachura, N.; Zhao, L.; Nygard, K.; Thompson, J. A.; Hadway, J.; Richardson, B. S.; Bureau, Y.; Borradaile, N.; Lee, T.-Y.; Regnault, T. R. H.
10.1101/2021.10.13.464235 — physiology — Posted on 2021-10-14
2327 ONTdeCIPHER: An amplicon-based nanopore sequencing pipeline for tracking pathogen variants
Cherif, E.; Thiam, F. S.; Salma, M.; RIVERA-INGRAHAM, G.; Justy, F.; Deremarque, T.; Breugnot, D.; Doudou, J.-c.; Gozlan, R. E.; Combe, M.
10.1101/2021.10.13.464242 — bioinformatics — Posted on 2021-10-14
2328 Functional single cell proteomic profiling of cells with abnormal DNA damage response dynamics
Su, P.-R.; You, L.; Beerens, C.; Bezstarosti, K.; Demmers, J.; Pabst, M.; Kanaar, R.; Hsu, C.-C.; Chien, M.-P.
10.1101/2021.10.13.464241 — bioengineering — Posted on 2021-10-14
2331 Calcium-independent but voltage-dependent secretion (CiVDS) mediates synaptic transmission in a mammalian central synapse
Wang, Y.; Huang, R.; Chai, Z.; Wang, C.; Du, X.; Hang, Y.; Xu, Y.; Li, J.; Jiang, X.; Wu, X.; Qiao, Z.; Li, Y.; Liu, B.; Zhang, X.; Cao, P.; Zhu, F.; Zhou, Z.
10.1101/2021.10.13.464194 — neuroscience — Posted on 2021-10-14
2334 Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons
Santulli, C.; Bon, C.; De Cecco, E.; Codrich, M.; Narkiewicz, J.; Parisse, P.; Perissinotto, F.; Santoro, C.; Persichetti, F.; Legname, G.; Espinoza, S.; Gustincich, S.
10.1101/2021.10.13.464204 — neuroscience — Posted on 2021-10-14
2335 Inhibition of TRPV4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism
Tzanoulinou, S.; Musardo, S.; Contestabile, A.; Bariselli, S.; Casarotto, G.; Magrinelli, E.; Jiang, Y.-H.; Jabaudon, D.; Bellone, C.
10.1101/2021.10.13.464215 — neuroscience — Posted on 2021-10-14
2336 The photobiology of the human circadian clock
Schoonderwoerd, R. A.; de Rover, M.; Janse, J. A. M.; Hirschler, L.; Willemse, C. R.; Scholten, L.; Klop, I.; van Berloo, S.; van Osch, M. J. P.; Swaab, D. F.; Meijer, J. H.
10.1101/2021.10.13.463655 — neuroscience — Posted on 2021-10-14
2338 Time-tagged ticker tapes for intracellular recordings
Lin, D.; Li, X.; Park, P.; Tang, B.; Shen, H.; Grimm, J. B.; Falco, N.; Baker, D.; Lavis, L. D.; Cohen, A. E.
10.1101/2021.10.13.463862 — neuroscience — Posted on 2021-10-14
2339 ALLOPURINOL BLOCKS THE FORMATION AND PROGRESSION OF AORTIC ANEURYSM IN A MOUSE MODEL OF MARFAN SYNDROME ACTING AS SCAVENGER OF REACTIVE OXYGEN SPECIES
Rodriguez-Rovira, I.; Arce, C.; Rycke, K. d.; Perez, B.; Carretereo, A.; Arbones, M.; Teixido-Tura, G.; Gomez-Cabrera, M. C.; Campuzano, V.; Jimenez-Altayo, F.; Egea, G.
10.1101/2021.10.13.464182 — pathology — Posted on 2021-10-14
2342 A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses
Wang, P.; Casner, R. G.; Nair, M. S.; Yu, J.; Guo, Y.; Wang, M.; Chan, J. F. W.; Cerutti, G.; Iketani, S.; Liu, L.; Sheng, Z.; Chen, Z.; Yuen, K.-Y.; Kwong, P. D.; Huang, Y.; Shapiro, L.; Ho, D. D.
10.1101/2021.10.13.464307 — microbiology — Posted on 2021-10-14
2343 An atlas of white matter anatomy, its variability, and reproducibility based on Constrained Spherical Deconvolution of diffusion MRI
Radwan, A. M.; Sunaert, S.; Schilling, K. G.; Descoteaux, M.; Landman, B. A.; Vandenbulcke, M.; Theys, T.; Dupont, P.; Emsell, L.
10.1101/2021.10.13.464139 — neuroscience — Posted on 2021-10-14
2344 Pleiotropic and Non-redundant Effects of an Auxin Importer in Setaria and Maize
Zhu, C.; Box, M. S.; Thiruppathi, D.; Hu, H.; Yu, Y.; Doust, A. N.; McSteen, P.; Kellogg, E. A.
10.1101/2021.10.14.464408 — plant biology — Posted on 2021-10-14
2346 Increased mTOR signaling, impaired autophagic flux and cell-to-cell viral transmission are hallmarks of SARS-CoV-2 infection.
Celeste Maktura, G.; Luscher Dias, T.; Pereira Zambalde, E.; Brenha, B.; R. Amorim, M.; Nunes Santos, L.; Buscaratti, L.; Gabriel de Angeli Elston, J.; Mara, C.; Camargo Silva Mancini, M.; Carolina Betim Pavan, I.; A. Toledo-Teixeira, D.; Bispo-dos-Santos, K.; L. Parise, P.; Primon Muraro, S.; Fabiano de Souza, G.; Paula Morelli, A.; Guilherme Salvino da Silva, L.; Maia Santos de Castro, I.; Oliveira Barbosa, G.; G. Ludwig, R.; L. Knittel, T.; D. Saccon, T.; A. Mori, M.; Granja, F.; F. Carvalho, H.; Lamberti Pinto da Silva, L.; I. Nakaya, H.; Luiz Proenca-Modena, J.; Moreira Simabuco, F.; Marq
10.1101/2021.10.13.464225 — cell biology — Posted on 2021-10-14
2347 The adenosine analogue prodrug ATV006 is orally bioavailable and has potent preclinical efficacy against SARS-CoV-2 and its variants
Cao, L.; Li, Y.; Yang, S.; Li, G.; Zhou, Q.; Sun, J.; Xu, T.; Yang, Y.; Zhu, T.; Huang, S.; Ji, Y.; Cong, F.; Luo, Y.; Zhu, Y.; Luan, H.; Zhang, H.; Chen, J.; Liu, X.; Wang, P.; Yu, Y.; Xing, F.; Ke, B.; Zheng, H.; Deng, X.; Zhang, W.; Li, C.; Zhang, Y.; Zhao, J.; Zhang, X.; Guo, D.
10.1101/2021.10.13.463130 — microbiology — Posted on 2021-10-14
2348 Public T-cell epitopes shared among SARS-CoV-2 variants are presented on prevalent HLA class I alleles
Meyer, S.; Blaas, I.; Bollineni, R. C.; Delic-Sarac, M.; Tran, T. T.; Knetter, C.; Dai, K.-Z.; Stove Madssen, T.; Vaage, J. T.; Gustavsen, A.; Yang, W.; Haug Nissen-Meyer, L. S.; Douvlataniotis, K.; Laos, M.; Nielsen, M. M.; Thiede, B.; Soraas, A.; Lund-Johansen, F.; Rustad, E. H.; Olweus, J.
10.1101/2021.10.13.463911 — immunology — Posted on 2021-10-14
2349 Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
Park, Y.-J.; De Marco, A.; Starr, T. N.; Liu, Z.; Pinto, D.; Walls, A. C.; Zatta, F.; Zepeda, S. K.; Bowen, J. E.; Sprouse, K. S.; Joshi, A.; Giurdanella, M.; Guarino, B.; Noack, J.; Abdelnabi, R.; Foo, S.-Y. C.; Lempp, F. A.; Benigni, F.; Snell, G.; Neyts, J.; Whelan, S. P.; Virgin, H. W.; Bloom, J. D.; Corti, D.; Pizzuto, M. S.; Veesler, D.
10.1101/2021.10.13.464254 — immunology — Posted on 2021-10-14
2350 Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation.
Geertsma, H. M.; Suk, T. R.; Ricke, K. M.; Horsthuis, K.; Parmasad, J.-L. A.; Fisk, Z.; Callaghan, S. M.; Rousseaux, M. W. C.
10.1101/2021.10.13.464123 — neuroscience — Posted on 2021-10-14
2353 Direct induction of human neurons from fibroblasts carrying the neuropsychiatric 22q11.2 microdeletion reveals transcriptome- and epigenome-wide alterations
Purmann, C.; Ang, C. E.; Tanabe, K.; Zhang, Y.; Kundu, S.; Danko, T.; Ma, S.; Mitelpunkt, A.; Wong, W. H.; Bernstein, J.; Hallmayer, J.; Aronow, B.; Südhof, T. C.; Kundaje, A.; Wernig, M.; Urban, A. E.
10.1101/2021.10.14.464344 — genomics — Posted on 2021-10-14
2354 pVHL regulates protein stability of TCF/LEF transcription factor family via ubiquitin-independent proteasomal degradation
Wang, C.; Rong, X.; Zhang, H.; Wang, B.; Bai, Y.; Liu, Y.; Lu, L.; Li, Y.; Sun, Y.; Zhao, C.; Zhou, J.
10.1101/2021.10.14.464355 — cell biology — Posted on 2021-10-14
2357 Kdm6b confers Tfdp1 with the competence to activate p53 signalling in regulating palatogenesis
Chai, Y.; Guo, T.; Han, X.; He, J.; Feng, J.; Jing, J.; Janeckova, E.; Lei, J.; Ho, T.-V.; Xu, J.
10.1101/2021.10.13.464272 — developmental biology — Posted on 2021-10-14
2360 Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation
Singh, A. P.; Wu, P.; Ryabichko, S.; Raimundo, J.; Swan, M.; Wieschaus, E.; Gregor, T.; Toettcher, J. E.
10.1101/2021.10.13.464280 — developmental biology — Posted on 2021-10-14
2361 In vivo mitochondrial matrix proteome profiling reveals RTN4IP1/OPA10 as an antioxidant NADPH oxidoreductase
Park, I.; Kim, K.-e.; Kim, J.; Bae, S.; Jung, M.; Choi, J.; Kwak, C.; Kang, M.-G.; Yoo, C.-M.; Mun, J. Y.; Liu, K.-H.; Kim, J.-S.; Suh, J. M.; Rhee, H.-W.
10.1101/2021.10.14.464368 — cell biology — Posted on 2021-10-14
2362 COLD ATMOSPHERIC PLASMA DIFFERENTIALLY AFFECTS CELL RENEWAL AND DIFFERENTIATION OF STEM CELLS AND APC-DEFICIENT-DERIVED TUMOR CELLS IN INTESTINAL ORGANOIDS
Hadefi, A.; Leprovots, M.; Thulliez, M.; Bastin, O.; Lefort, A.; Libert, F.; Nonclercq, A.; Delchambre, A.; Reniers, F.; Deviere, J.; Garcia, M.-I.
10.1101/2021.10.13.464287 — cell biology — Posted on 2021-10-14
2364 Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation
Morthorst, S. K.; Nielsen, C.; Farinelli, P.; Anvarian, Z.; Rasmussen, C. B. R.; Serra-Marques, A.; Grigoriev, I.; Altelaar, M.; Furstenberg, N.; Ludwig, A.; Akhmanova, A.; Christensen, S. T.; Pedersen, L. B.
10.1101/2021.10.14.464392 — cell biology — Posted on 2021-10-14
2368 Making Genomic Surveillance Deliver: A Lineage Classification and Nomenclature System to Inform Rabies Virus Elimination
Campbell, K.; Gifford, R. J.; Singer, J.; Hill, V.; O'Toole, A.; Rambaut, A.; Hampson, K.; Brunker, K.
10.1101/2021.10.13.464180 — genomics — Posted on 2021-10-14
2369 DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci
Bader, A. S.; Luessing, J.; Hawley, B. R.; Skalka, G. L.; Lu, W.-T.; Lowndes, N. F.; Bushell, M.
10.1101/2021.10.14.464298 — cell biology — Posted on 2021-10-14
2371 Modular, robust and extendible multicellular circuit design in yeast
Carignano, A.; Chen, D. H.; Mallory, C.; Wright, C.; Seelig, G.; Klavins, E.
10.1101/2021.10.13.464175 — synthetic biology — Posted on 2021-10-14
2372 Prion-like α-synuclein pathology in the brains of infants: Krabbe disease as a novel seed-competent α-synucleinopathy
Hatton, C.; Ghanem, S. S.; Koss, D.; Abdi, I. Y.; Gibbons, E.; Guerreiro, R.; Bras, J.; International DLB Genetics Consortium, ; Walker, L.; Gelpi, E.; Heywood, W.; Outeiro, T. F.; Attems, J.; McFarland, B.; Forsyth, R.; El-Agnaf, O. M.; Erskine, D.
10.1101/2021.10.12.463948 — pathology — Posted on 2021-10-14
2373 A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells.
Hinzman, C. P.; Bansal, S.; Li, Y.; Iliuk, A.; Girgis, M.; Singh, B.; Herremans, K. M.; Trevino, J. G.; Singh, V. K.; Banerjee, P. P.; Cheema, A. K.
10.1101/2021.10.12.464079 — cancer biology — Posted on 2021-10-14
2376 FAIRly big: A framework for computationally reproducible processing of large-scale data
Wagner, A. S.; Waite, L. K.; Wierzba, M.; Hoffstaedter, F.; Waite, A. Q.; Poldrack, B.; Eickhoff, S. B.; Hanke, M.
10.1101/2021.10.12.464122 — bioinformatics — Posted on 2021-10-14
2377 Eoulsan 2: an efficient workflow manager for reproducible bulk, long-read and single-cell transcriptomics analyses
Lehmann, N.; Perrin, S.; Wallon, C.; Bauquet, X.; Deshaies, V.; Firmo, C.; Du, R.; Berthelier, C.; Hernandez, C.; Michaud, C.; Thieffry, D.; Le Crom, S.; Thomas-Chollier, M.; Jourdren, L.
10.1101/2021.10.13.464219 — bioinformatics — Posted on 2021-10-14
2378 netCRS: Network-based comorbidity risk score for prediction of myocardial infarction using biobank-scaled PheWAS data
Nam, Y.; Jung, S.-H.; Verma, A.; Sriram, V.; Won, H.-H.; Yun, J.-S.; Regeneron Genetics Center, ; Kim, D.
10.1101/2021.10.12.464134 — bioinformatics — Posted on 2021-10-14
2382 From compartments to gene loops: Functions of the 3D genome in the human brain
Rahman, S.; Dong, P.; Apontes, P.; Fernando, M. B.; Townsley, K. G.; Girdhar, K.; Bendl, J.; Shao, Z.; Misir, R.; Tsankova, N.; Kleopoulos, S. P.; Brennand, K. J.; Fullard, J. F.; Roussos, P.
10.1101/2021.10.12.464094 — genomics — Posted on 2021-10-14
2386 A Proposed Unified Mitotic Chromosome Architecture
Sedat, J.; McDonald, A.; Kasler, H. G.; Verdin, E.; Cang, H.; Murre, C.; Elbaum, M.
10.1101/2021.10.14.464227 — cell biology — Posted on 2021-10-14
2388 A multi-dataset evaluation of frame censoring for task-based fMRI
Jones, M. S.; Zhu, Z.; Bajracharya, A.; Luor, A.; Peelle, J. E.
10.1101/2021.10.12.464075 — neuroscience — Posted on 2021-10-14
2391 Microscopic Quantification of Oxygen Consumption across Cortical Layers
Mächler, P.; Fomin-Thunemann, N.; Thunemann, M.; Saetra, M. J.; Desjardins, M.; Kılıc, K.; Sencan, I.; Li, B.; Saisan, P.; Cheng, Q.; Weldy, K. L.; Boas, D. A.; Buxton, R. B.; Einevoll, G. T.; Dale, A. M.; Sakadzic, S.; Devor, A.
10.1101/2021.10.13.464176 — neuroscience — Posted on 2021-10-14
2392 Creatine transporter deficient rat show motor dysfunction linked with cerebellar alterations and muscle creatine deficiency without muscle atrophy
Duran-Trio, L.; Fernandes-Pires, G.; Grosse, J.; Soro-Arnaiz, I.; Roux-Petronelli, C.; Binz, P.-A.; De Bock, K.; Cudalbu, C.; Sandi, C.; Braissant, O.
10.1101/2021.10.12.464080 — pathology — Posted on 2021-10-14
2393 Impact of baseline culture conditions of mouse-derived cancer organoids when determining therapeutic response and tumor heterogeneity
DeStefanis, R. A.; Olson, A. M.; DeZeeuw, A. K.; Gillette, A. A.; Sha, G. C.; Johnson, K. A.; Kratz, J. D.; Pasch, C. A.; Clipson, L.; Skala, M. C.; Deming, D. A.
10.1101/2021.10.12.464087 — cancer biology — Posted on 2021-10-14
2394 Investigating the Role of Chromatin Remodeler FOXA1 in Ferroptotic Cell Death
Logie, E.; Maes, L.; Van Meenen, J.; De Rijk, P. H.; Strazisar, M.; Joris, G.; Cuypers, B.; Laukens, K.; Berghe, W. V.
10.1101/2021.10.13.461056 — cancer biology — Posted on 2021-10-14
2396 Crop loss identification at field parcel scale using satellite remote sensing and machine learning
Hiremath, S.; Wittke, S.; Palosuo, T.; Kaivosoja, J.; Tao, F.; Proll, M.; Puttonen, E.; Peltonen-Sainio, P.; Marttinen, P.; Mamitsuka, H.
10.1101/2021.05.07.443072 — bioinformatics — Posted on 2021-10-14
2398 PoSTcode: Probabilistic image-based spatial transcriptomics decoder
Gataric, M.; Park, J. S.; Li, T.; Vaskivskyi, V.; Svedlund, J.; Strell, C.; Roberts, K.; Nilsson, M.; Yates, L. R.; Bayraktar, O.; Gerstung, M.
10.1101/2021.10.12.464086 — bioinformatics — Posted on 2021-10-14
2402 Multi-parameter photon-by-photon hidden Markov modeling
Harris, P. D.; Narducci, A.; Gebhardt, C.; Cordes, T.; Weiss, S.; Lerner, E.
10.1101/2021.04.08.439035 — biophysics — Posted on 2021-10-14
2404 Chromatin remodelling by INO80 at transcription pause sites promotes premature termination of mRNA synthesis
Luzzi, S.; Szachnowski, U.; Greener, S.; Schumacher, K.; Fulton, S.; Han, K. H.; Darke, J.; Piccinno, R.; Lafon, A.; Pugh, B. F.; Devys, D.; Tora, L.; Morillon, A.; Papamichos-Chronakis, M.
10.1101/2020.03.02.973685 — molecular biology — Posted on 2021-10-14
2406 Additive, synergic and antagonistic interactions between maternal immune activation and peripubertal stress in cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome.
Capellan, R.; Orihuel, J.; Marcos, A.; Ucha, M.; Moreno-Fernandez, M.; Casquero-Veiga, M.; Soto-Montenegro, M. L.; Desco, M.; Oteo-Vives, M.; Ibanez-Moragues, M.; Magro-Calvo, N.; Morcillo, M. A.; Ambrosio, E.; Higuera-Matas, A.
10.1101/2021.10.11.463760 — neuroscience — Posted on 2021-10-14
2407 C9orf72-derived poly-GA DPRs undergo endocytic uptake in iNPC-derived astrocytes and spread to motor neurons
Marchi, P. M.; Marrone, L.; Brasseur, L.; Bousset, L.; Webster, C. P.; Destro, M.; Smith, E. F.; Walther, C. G.; Alfred, V.; Marroccella, R.; Robinson, D.; Shaw, A. C.; Wan, L. M.; Grierson, A.; Ebbens, S. J.; De Vos, K. J.; Hautbergue, G. M.; Ferraiuolo, L.; Melki, R.; Azzouz, M.
10.1101/2021.10.11.463891 — neuroscience — Posted on 2021-10-14
2410 Annotation of glycolysis, gluconeogenesis, and trehaloneogenesis pathways provide insight into carbohydrate metabolism in the Asian citrus psyllid
Tamayo, B.; Kercher, K.; Vosburg, C.; Massimino, C.; Jernigan, M. R.; Hasan, D. L.; Harper, D.; Mathew, A.; Adkins, S.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Panitz, N.; Mueller, L. A.; Hunter, W. B.; Benoit, J. B.; Brown, S. J.; Delia, T.; Saha, S.
10.1101/2021.10.11.463922 — bioinformatics — Posted on 2021-10-14
2411 Assessing the impact of grassland management on landscape multifunctionality
Neyret, M.; Fischer, M.; Allan, E.; Hoelzel, N.; Klaus, V.; Kleinebecker, T.; Krauss, J.; Le Provost, G.; Peter, S.; Schenk, N.; Simons, N. K.; van der Plas, F.; Binkenstein, J.; Boerschig, C.; Jung, K.; Prati, D.; Schaefer, D.; Schaefer, M.; Schoening, I.; Schrumpf, M.; Tschapka, M.; Westphal, C.; Manning, P.
10.1101/2020.07.17.208199 — ecology — Posted on 2021-10-14
2412 Monitoring fish communities through environmental DNA metabarcoding in the fish pass system of the second largest hydropower plant in the world
Dal Pont, G.; Ritter, C. D.; Olivotto Agostinis, A.; Valeska Stika, P.; Horodesky, A.; Cozer, N.; Balsanelli, E.; Mader Netto, O. S.; Henn, C.; Ostrensky, A.; Pie, M. R.
10.1101/2021.08.17.456687 — ecology — Posted on 2021-10-14
2414 Evaluation of microbiome enrichment and host DNA depletion in human vaginal samples using Oxford Nanopore's adaptive sequencing
Marquet, M.; Zoellkau, J.; Pastuschek, J.; Viehweger, A.; Schleussner, E.; Makarewicz, O.; Pletz, M. W.; Ehricht, R.; Brandt, C.
10.1101/2021.09.15.460450 — molecular biology — Posted on 2021-10-14
2415 Hippocampal CA1 pyramidal cells do not receive monosynaptic input from thalamic nucleus reuniens
Andrianova, L.; Brady, E. S.; Margetts-Smith, G.; Kohli, S.; McBain, C. J.; Craig, M. T.
10.1101/2021.09.30.462517 — neuroscience — Posted on 2021-10-14
2417 Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania
Cuypers, B.; Meysman, P.; Erb, I.; Bittremieux, W.; Valkenborg, D.; Baggerman, G.; Mertens, I.; Sundar, S.; Khanal, B.; Notredame, C.; Dujardin, J.-C.; Domagalska, M. A.; Laukens, K.
10.1101/2021.09.14.460245 — systems biology — Posted on 2021-10-14
2420 Tissue-wide coordination of calcium signaling regulates the epithelial stem cell pool during homeostasis
Moore, J. L.; Gao, F.; Matte-Martone, C.; Du, S.; Lathrop, E.; Ganesan, S.; Shao, L.; Bhaskar, D.; Cox, A.; Hendry, C. E.; Rieck, B. A.; Krishnaswamy, S.; Greco, V.
10.1101/2021.10.12.464066 — cell biology — Posted on 2021-10-14
2424 Diversity of reptile sex chromosome evolution revealed by cytogenetic and linked-read sequencing
Zhu, Z.; Matsubara, K.; Shams, F.; Dobry, J.; Wapstra, E.; Gamble, T.; Sarre, S. D.; Georges, A.; Marshall Graves, J. A.; Zhou, Q.; Ezaz, T.
10.1101/2021.10.13.462063 — genomics — Posted on 2021-10-14
2427 Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer
Chang, C. A.; Jen, J.; Jiang, S.; Sayad, A.; Mer, A. S.; Brown, K. R.; Nixon, A.; Dhabaria, A.; Tang, K. H.; Venet, D.; Sotiriou, C.; Deng, J.; Wong, K.-k.; Adams, S.; Meyn, P.; Heguy, A.; Skok, J.; Tsirigos, A.; Ueberheide, B.; Moffat, J.; Singh, A.; Haibe-Kains, B.; Khodadadi-Jamayran, A.; Neel, B. G.
10.1101/2020.08.28.273029 — cancer biology — Posted on 2021-10-13
2428 Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter
Bera, S. C.; America, P. P. B.; Maatsola, S.; Seifert, M.; Ostrofet, E.; Cnossen, J.; Spermann, M.; Papini, F. S.; Depken, M.; Malinen, A. M.; Dulin, D.
10.1101/2021.10.13.464252 — biophysics — Posted on 2021-10-13
2433 Epigenetic clock and methylation studies in gray short-tailed opossums
Horvath, S.; Haghani, A.; Zoller, J. A.; Raj, K.; Sinha, I.; Talbot, A.; Aviles Ruiz, Y.; Sears, K. E.
10.1101/2021.10.13.464301 — evolutionary biology — Posted on 2021-10-13
2437 Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP)
Kurt, F.; Leventhal, G. E.; Spalinger, M. R.; Anthamatten, L.; Rogalla von Bieberstein, P.; Rogler, G.; Lacroix, C.; de Wouters, T.
10.1101/2021.10.13.464188 — microbiology — Posted on 2021-10-13
2441 Digital 3D Brain MRI Arterial Territories Atlas
Liu, C.-F.; Hsu, J.; Xu, X.; Kim, N. G.; Sheppard, S.; Meier, E.; Miller, M.; Hillis, A. E.; Faria, A. V.
10.1101/2021.05.03.442478 — neuroscience — Posted on 2021-10-13
2447 Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages
Howick, V. M.; Peacock, L.; Kay, C.; Collett, C.; Gibson, W.; Lawniczak, M. K.
10.1101/2021.10.13.463681 — genomics — Posted on 2021-10-13
2449 Archaeal origins of gamete fusion
Moi, D.; Nishio, S.; Li, X.; Valansi, C.; Langleib, M.; Brukman, N. G.; Flyak, K.; Dessimoz, C.; de Sanctis, D.; Tunyasuvunakool, K.; Jumper, J.; Grana, M.; Romero, H.; Aguilar, P. S.; Jovine, L.; Podbilewicz, B.
10.1101/2021.10.13.464100 — evolutionary biology — Posted on 2021-10-13
2452 Taxonomic classification methods reveal a new subgenus in the paramyxovirus subfamily Orthoparamyxovirinae
Wells, H. L.; Loh, E.; Nava, A.; Lee, M. H.; Lee, J.; Sukor, J. R. A.; Navarrete-Macias, I.; Liang, E.; Firth, C.; Epstein, J.; Rostal, M.; Zambrana-Torrelio, C.; Murray, K. A.; Daszak, P.; Goldstein, T.; Mazet, J. A. K.; Lee, B.; Hughes, T.; Durigon, E. L.; Anthony, S. J.
10.1101/2021.10.12.464153 — microbiology — Posted on 2021-10-13
2453 Guanosine-specific single-stranded ribonuclease effectors of a phytopathogenic fungus potentiate host immune responses
Kumakura, N.; Singkaravanit-Ogawa, S.; Gan, P.; Tsushima, A.; Ishihama, N.; Watanabe, S.; Seo, M.; Iwasaki, S.; Narusaka, M.; Narusaka, Y.; Takano, Y.; Shirasu, K.
10.1101/2021.10.13.464185 — microbiology — Posted on 2021-10-13
2456 The cnf1 gene is associated to an expanding Escherichia coli ST131 H30Rx/C2 sublineage and confers a competitive advantage for host colonization
TSOUMTSA MEDA, L. L.; LANDRAUD, L.; PETRACCHINI, S.; DESCORPS-DECLERE, S.; PERTHAME, E.; NAHORI, M.-a.; RAMIREZ FINN, L.; INGERSOLL, M. A.; PATINO-NAVARETE, R.; GLASER, P.; DUSSURGET, O.; DENAMUR, E.; METTOUCHI, A.; LEMICHEZ, E.
10.1101/2021.10.13.464032 — microbiology — Posted on 2021-10-13
2457 Transkingdom Analysis of the Female Reproductive Tract Reveals Bacteriophages Form Communities
Madere, F. S.; Sohn, M.; Winbush, A.; Barr, B.; Grier, A.; Java, J.; Meiring, T.; Williamson, A.-L.; Bekker, L.-G.; Adler, D. H.; Monaco, C. L.
10.1101/2021.10.12.464088 — microbiology — Posted on 2021-10-13
2460 Rates of primary production in groundwater rival those in oligotrophic marine systems
Overholt, W. A.; Trumbore, S.; Xu, X.; Bornemann, T. L. V.; Probst, A. J.; Krüger, M.; Herrmann, M.; Thamdrup, B.; Bristow, L.; Taubert, M.; Schwab, V. F.; Hölzer, M.; Marz, M.; Küsel, K.
10.1101/2021.10.13.464073 — microbiology — Posted on 2021-10-13
2461 SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy
Ryu, J. K.; Sozmen, E. G.; Dixit, K.; Montano, M.; Matsui, Y.; Liu, Y.; Helmy, E.; Deerinck, T. J.; Yan, Z.; Schuck, R.; Acevedo, R. M.; Spencer, C. M.; Thomas, R.; Pico, A. R.; Zamvil, S. S.; Lynch, K. L.; Ellisman, M. H.; Greene, W. C.; Akassoglou, K.
10.1101/2021.10.12.464152 — immunology — Posted on 2021-10-13
2462 Low antigen abundance limits efficient T-cell recognition of highly conserved regions of SARS-CoV-2
Swaminathan, S.; Lineburg, K.; Ambalathingal, G.; Crooks, P.; Grant, E.; Mohan, S.; Raju, J.; Panikkar, A.; Le Texier, L.; Tong, Z.; Chew, K.; Neller, M.; Gowda, H.; Short, K.; Gras, S.; Smith, C.; Khanna, R.
10.1101/2021.10.13.464181 — immunology — Posted on 2021-10-13
2463 AUG-3387, a Human-Derived Monoclonal Antibody Neutralizes SARS-CoV-2 Variants and Reduces Viral Load from Therapeutic Treatment of Hamsters In Vivo
Emig, C. J.; Mena, M. A.; Henry, S. J.; Vitug, A.; Ventura, C. J.; Fox, D.; Nguyenla, X. H.; Xu, H.; Moon, C.; Sahakijjpijarn, S.; Kuehl, P. J.; Revelli, D.; Cui, Z.; Williams, R. O.; Christensen, D. J.
10.1101/2021.10.12.464150 — pharmacology and toxicology — Posted on 2021-10-13
2464 A dual endosymbiosis drives nutritional adaptation to hematophagy in the invasive tick Hyalomma marginatum
Buysse, M.; Floriano, A. M.; Gottlieb, Y.; Nardi, T.; Comandatore, F.; Olivieri, E.; Giannetto, A.; Palomar Urbina, A. M.; Makepeace, B.; Bazzocchi, C.; Cafiso, A.; Sassera, D.; Duron, O.
10.1101/2021.10.12.464044 — evolutionary biology — Posted on 2021-10-13
2466 Codiversification of gut microbiota with humans
Suzuki, T. A.; Fitzstevens, L.; Schmidt, V. T.; Enav, H.; Huus, K.; Mbong, M.; Adegbite, B. R.; Zinsou, J. F.; Esen, M.; Velavan, T. P.; Adegnika, A. A.; Song, L. H.; Spector, T. D.; Muehlbauer, A. L.; Marchi, N.; Blekhman, R.; Segurel, L.; Youngblut, N. D.; Kremsner, P.; Ley, R. E.
10.1101/2021.10.12.462973 — evolutionary biology — Posted on 2021-10-13
2467 Frugivore gut passage increases seed germination: an updated meta-analysis
Rogers, H. S.; Cavazos, B. R.; Gawel, A. M.; Karnish, A. T.; Ray, C. A.; Rose, E.; Thierry, H.; Fricke, E. C.
10.1101/2021.10.12.462022 — ecology — Posted on 2021-10-13
2469 A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
Greaney, A. J.; Starr, T. N.; Eguia, R. T.; Loes, A. N.; Khan, K.; Karim, F.; Cele, S.; Bowen, J. E.; Logue, J. K.; Corti, D.; Veesler, D.; Chu, H. Y.; Sigal, A.; Bloom, J. D.
10.1101/2021.10.12.464114 — microbiology — Posted on 2021-10-13
2470 Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown
Aydin, S.; Pareja, J.; Schallenberg, V. M.; Klopstein, A.; Gruber, T.; Page, N.; Kaba, E.; Deutsch, U.; Johnson, A.; Schenk, M.; Merkler, D.; Engelhardt, B.
10.1101/2021.10.12.464035 — immunology — Posted on 2021-10-13
2471 Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons
Deng, C.; Moradi, M.; Reinhard, S.; Ji, C.; Jablonka, S.; Hennlein, L.; Lueningschroer, P.; Doose, S.; Sauer, M.; Sendtner, M.
10.1101/2021.10.12.463928 — neuroscience — Posted on 2021-10-13
2473 Early evolution of beetles regulated by the end-Permian deforestation
Zhao, X.; Yu, Y.; Clapham, M.; Yan, E.; Chen, J.; Jarzembowski, E. A.; Zhao, X.; Wang, B.
10.1101/2021.10.12.464043 — paleontology — Posted on 2021-10-13
2475 Mapping tumor spheroid mechanics in dependence of 3D microenvironment stiffness and degradability by Brillouin microscopy
Mahajan, V.; Beck, T.; Gregorczyk, P.; Ruland, A.; Alberti, S.; Guck, J.; Werner, C.; Schluessler, R.; Taubenberger, A. V.
10.1101/2021.10.12.464071 — biophysics — Posted on 2021-10-13
2476 Ubiquitin Proteasome Pathway annotation in Diaphorina citri can reveal potential targets for RNAi based pest management
Tank, W.; Shippy, T.; Thate, A.; Massimino, C.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; Delia, T.; Saha, S.
10.1101/2021.10.11.464014 — bioinformatics — Posted on 2021-10-13
2477 Functional single cell selection and annotated profiling of dynamically changing cancer cells
You, L.; Su, P.-R.; Betjes, M.; Ghadiri Rad, R.; Chou, T.-C.; Beerens, C.; van Oosten, E.; Leufkens, F.; Gasecka, P.; Muraro, M.; van Tol, R.; van Steenderen, D.; Farooq, S.; Hardillo, J.; Baatenburg de Jong, R.; Brinks, D.; Chien, M.-P.
10.1101/2021.10.12.464054 — bioengineering — Posted on 2021-10-13
2480 Membrane permeability differentiation at the lipid divide
Lapinska, U.; Kahveci, Z.; Irwin, N.; Milner, D.; Santoro, A. E. S.; Richards, T. A.; Pagliara, S.
10.1101/2021.10.12.464042 — evolutionary biology — Posted on 2021-10-13
2481 Multi-parameter optical imaging of immune cell activity in chimeric antigen receptor T-cell and checkpoint blockade therapies
Xie, J.; Rami, F. E.; Zhou, K.; Simonetta, F.; Chen, Z.; Zheng, X.; Chen, M.; Balakrishnan, P. B.; Dai, S.-Y.; Murty, S.; Alam, I. S.; Baker, J.; Negrin, R. S.; Gambhir, S. S.; Rao, J.
10.1101/2021.10.11.463603 — immunology — Posted on 2021-10-13
2482 Intermanual transfer of visuomotor learning is facilitated by a cognitive strategy
De Havas, J.; Haggard, P.; Gomi, H.; Bestmann, S.; Ikegaya, Y.; Hagura, N.
10.1101/2021.10.12.464030 — neuroscience — Posted on 2021-10-13
2486 Individual alpha power predicts language comprehension
Wang, P.; He, Y.; Maess, B.; Yue, J.; Chen, L.; Brauer, J.; Friederici, A. D.; Knoesche, T. R.
10.1101/2021.10.12.464065 — neuroscience — Posted on 2021-10-13
2489 Ex Vivo Culture Models of Hidradenitis Suppurativa for defining molecular pathogenesis and treatment efficacy of novel drugs
Goliwas, K.; Kashyap, M. P.; Khan, J.; Sinha, R.; Weng, Z.; Oak, A. S.; Jin, L.; Attigadda, V.; Lee, M. B.; Elmets, C. A.; Mukhtar, M. S.; Deshane, J. S.; Athar, M.
10.1101/2021.10.11.464007 — pathology — Posted on 2021-10-13
2492 RNAi screening of RING/U-box domain ubiquitin ligases identifies critical regulators of stem cells and tissue regeneration in planarians
Allen, J. M.; Balagtas, M.; Barajas, E.; Cano Macip, C.; Alvarez Zepeda, S.; Iberkleid, I.; Duncan, E. M.; Zayas, R. M.
10.1101/2021.10.12.463740 — developmental biology — Posted on 2021-10-13
2493 Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma
Marcus, R. K.; Ferri-Borgogno, S.; Hosein, A.; Foo, W. C.; Ghosh, B.; Zhao, J.; Rajapakshe, K.; Brugarolas, J.; Maitra, A.; Gupta, S.
10.1101/2021.10.12.464103 — cell biology — Posted on 2021-10-13
2494 Tissue-wide coordination of calcium signaling regulates the epithelial stem cell pool during homeostasis
Moore, J. L.; Gao, F.; Matte-Martone, C.; Du, S.; Lathrop, E.; Ganesan, S.; Shao, L.; Bhaskar, D.; Cox, A.; Hendry, C. E.; Rieck, B. A.; Krishnaswamy, S.; Greco, V.
10.1101/2021.10.12.464066 — cell biology — Posted on 2021-10-13
2495 Recording of cellular physiological histories along optically readable self-assembling protein chains
Linghu, C.; An, B.; Shpokayte, M.; Celiker, O. T.; Shmoel, N.; Zhang, C.; Park, W. M.; Ramirez, S.; Boyden, E. S.
10.1101/2021.10.13.464006 — synthetic biology — Posted on 2021-10-13
2496 Haploinsufficient tumour suppressor PRP4K is negatively regulated during epithelial-to-mesenchymal transition
Clarke, L. E.; Cook, A.; Mathavarajah, S.; Bera, A.; Salsman, J.; Habib, E.; Van Iderstine, C.; Bydoun, M.; Lewis, S. M.; Dellaire, G.
10.1101/2020.04.19.043851 — cancer biology — Posted on 2021-10-13
2497 Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization
Arellano-Santoyo, H.; Hernandez-Lopez, R. A.; Stokasimov, E.; Wang, R. Y.; Pellman, D.; Leschziner, A. E.
10.1101/2021.10.12.464151 — biophysics — Posted on 2021-10-13
2499 Immunomodulatory Contribution of Mast Cells to the Regenerative Biomaterial Microenvironment
Wang, R. M.; Mesfin, J.; Ungerleider, J.; Kawakami, Y.; Kawakami, Y.; Kawakami, T.; Christman, K.
10.1101/2020.07.31.231852 — bioengineering — Posted on 2021-10-13
2501 Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis
Mund, M.; Tschanz, A.; Wu, Y.-L.; Frey, F.; Mehl, J. L.; Kaksonen, M.; Avinoam, O.; Schwarz, U. S.; Ries, J.
10.1101/2021.10.12.463947 — cell biology — Posted on 2021-10-13
2503 A stress-reduced passaging technique improves the viability of human pluripotent cells
Takahashi, K.; Okubo, C.; Nakamura, M.; Iwasaki, M.; Kawahara, Y.; Tabata, T.; Miyamoto, Y.; Woltjen, K.; Yamanaka, S.
10.1101/2021.10.12.464142 — cell biology — Posted on 2021-10-13
2504 The mechanochemical origins of the microtubule sliding motility within the kinesin-5 domain organization
Nithiananatham, S.; Iwanski, M. K.; Gaska, I.; Pandey, H.; Bodrug, T.; Inagaki, S.; Major, J.; Brouhard, G.; Gheber, L.; Rosenfeld, S. S.; Forth, S. T.; Hendricks, A. G.; Al-Bassam, J.
10.1101/2021.10.12.463902 — cell biology — Posted on 2021-10-13
2507 Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
Gomez, J. L.; Bonaventura, J.; Keighron, J.; Wright, K. M.; Marable, D. L.; Rodriguez, L. A.; Lam, S.; Carlton, M. L.; Ellis, R. J.; Jordan, C.; Bi, G.-H.; Solis, O.; Pignatelli, M.; Bannon, M. J.; Xi, Z.-X.; Tanda, G.; Michaelides, M.
10.1101/2020.08.29.273482 — neuroscience — Posted on 2021-10-13
2509 The fungicide Tebuconazole induces electromechanical cardiotoxicity in murine hearts
Santos-Miranda, A.; Joviano-Santos, J. V.; Cruz-Nascimento, T.; Souza, D. S.; Marques, L.; Roman-Campos, D.
10.1101/2021.10.13.464222 — pharmacology and toxicology — Posted on 2021-10-13
2510 New markers for qPCR detection of the dinoflagellate Alexandrium catenella in Chile
Espinoza, J.; Yarimizu, K.; Nagai, S.; Espinoza Gonzalez, O.; Guzman, L.; Fuenzalida, G.
10.1101/2021.10.11.463552 — genetics — Posted on 2021-10-13
2512 Environmentally dependent and independent control of cell shape determination by Rho GTPase regulators in melanoma
Dent, L. G.; Curry, N.; Sparks, H.; Bousgouni, V.; Maioli, V.; Kumar, S.; Munro, I.; Dunsby, C.; Bakal, C.
10.1101/2021.10.11.463377 — cell biology — Posted on 2021-10-13
2514 Structural and functional asymmetry of the neonatal cerebral cortex
Williams, L. Z. J.; Fitzgibbon, S. P.; Bozek, J.; Winkler, A. M.; Dimitrova, R.; Poppe, T.; Schuh, A.; Makropoulos, A.; Cupitt, J.; O'Muircheartaigh, J.; Duff, E.; Cordero-Grande, L.; Price, A. N.; Hajnal, J. V.; Rueckert, D.; Smith, S. M.; Edwards, D.; Robinson, E. C.
10.1101/2021.10.13.464206 — neuroscience — Posted on 2021-10-13
2516 Non-micronized and micronized curcumin do not prevent the behavioral and neurochemical effects induced by acute stress in zebrafish
Sachett, A.; Gallas-Lopes, M.; Benvenutti, R.; Marcon, M.; Linazzi, A. M.; Aguiar, G. P. S.; Herrmann, A. P.; Oliveira, J. V.; Siebel, A. M.; Piato, A.
10.1101/2021.10.11.463974 — neuroscience — Posted on 2021-10-13
2522 Chemical inhibition of auxin inactivation pathway uncovers the metabolic turnover of auxin homeostasis
Fukui, K.; Arai, K.; Tanaka, Y.; Aoi, Y.; Kukshal, V.; Jez, J. M.; Kubes, M. F.; Napier, R.; Zhao, Y.; Kasahara, H.; Hayashi, K.-i.
10.1101/2021.10.12.464031 — plant biology — Posted on 2021-10-13
2523 Haplotype mapping uncovers unexplored variation in wild and domesticated soybean at the major protein locus cqProt-003
Marsh, J. I.; Hu, H.; Petereit, J.; Bayer, P. E.; Valliyodan, B.; Batley, J.; Nguyen, H. T.; Edwards, D.
10.1101/2021.10.12.464159 — plant biology — Posted on 2021-10-13
2524 The plant-specific SCL30a SR protein regulates ABA-dependent seed traits and salt stress tolerance during germination
Laloum, T.; Carvalho, S. D.; Martin, G.; Richardson, D.; Cruz, T. M. D.; Carvalho, R. F.; Stecca, K. L.; Kinney, A. J.; Zeidler, M.; Barbosa, I. C. R.; Duque, P.
10.1101/2021.10.13.464208 — plant biology — Posted on 2021-10-13
2526 A molecular framework for proximal secondary vein branching in the Arabidopsis thaliana embryo
Kastanaki, E.; Blanco-Tourinan, N.; Sarazin, A.; Sturchler, A.; Gujas, B.; Rodriguez-Villalon, A.
10.1101/2021.10.12.464048 — plant biology — Posted on 2021-10-13
2527 Loss of KRASG12D feedback regulation involving splicing factor SRSF1 accelerates pancreatic cancer
Wan, L.; Lin, K.-T.; Rahman, M. A.; Wang, Z.; Jensen, M. A.; Park, Y.; Tuveson, D. A.; Krainer, A. R.
10.1101/2021.10.13.464210 — cancer biology — Posted on 2021-10-13
2528 Lineage Recording Reveals the Phylodynamics, Plasticity and Paths of Tumor Evolution
Yang, D.; Jones, M. G.; Naranjo, S.; Rideout, W. M.; Min, K. H. J.; Ho, R.; Wu, W.; Replogle, J. M.; Page, J. L.; Quinn, J. J.; Horns, F.; Qiu, X.; Chen, M. Z.; Freed-Pastor, W. A.; McGinnis, C. S.; Patterson, D. M.; Gartner, Z. J.; Chow, E. D.; Bivona, T. G.; Chan, M. M.; Yosef, N.; Jacks, T.; Weissman, J. S.
10.1101/2021.10.12.464111 — cancer biology — Posted on 2021-10-13
2532 Getting out of a mammalian egg: the egg tooth and caruncle of the echidna
Fenelon, J. C.; Bennetts, A.; Anthwal, N.; Pyne, M.; Johnston, S. D.; Evans, A. R.; Tucker, A. S.; Renfree, M. B.
10.1101/2021.10.12.464116 — evolutionary biology — Posted on 2021-10-13
2533 Hydrophobicity in clearwing butterflies and moths: impact of scale micro and nanostructure, and trade-off with optical transparency
Gomez, D.; Pairraire, J.; Pinna, C.; Arias, M.; Houssin, C.; Barbut, J.; Berthier, S.; Andraud, C.; Ondarcuhu, T.; Elias, M.
10.1101/2021.10.11.463886 — evolutionary biology — Posted on 2021-10-13
2534 Dormant replication origin firing links replication stress to whole chromosomal instability in human cancer
Schmidt, A.-K.; Boehly, N.; Zhang, X.; Slusarenko, B. O.; Hennecke, M.; Kschischo, M.; Bastians, H.
10.1101/2021.10.11.463929 — cell biology — Posted on 2021-10-13
2535 Brain X chromosome inactivation is not random and can protect from paternally inherited neurodevelopmental disease.
Szelenyi, E. R.; Fisenne, D.; Knox, J. E.; Harris, J. A.; Gornet, J. A.; Palaniswamy, R.; Kim, Y.; Venkataraju, K. U.; Osten, P.
10.1101/458992 — neuroscience — Posted on 2021-10-13
2536 Behavioral state tunes mouse vision to ethological features through pupil dilation
Franke, K.; Willeke, K. F.; Ponder, K.; Galdamez, M.; Muhammad, T.; Patel, S.; Froudarakis, E.; Reimer, J.; Sinz, F.; Tolias, A.
10.1101/2021.09.03.458870 — neuroscience — Posted on 2021-10-13
2538 Oral glucose feeding enhances adherence of quiescent lymphocytes to fibronectin via non-canonical insulin signalling.
Mallu, A. C. T.; Sivagurunathan, S.; Paul, D.; Aggarwal, H.; Nathan, A. A.; Ravi, M. M.; Boppana, R.; Jagavelu, K.; Santra, M. K.; Dixit, M.
10.1101/2021.10.13.464163 — physiology — Posted on 2021-10-13
2539 Control of protein activity by photoinduced spin polarized charge reorganization
Ghosh, S.; Ghosh, K. B.; Levy, D.; Scheerer, D.; Riven, I.; Shin, J.; Gray, H.; Naaman, R.; Haran, G.
10.1101/2021.10.12.464058 — biophysics — Posted on 2021-10-13
2540 STOICHIOMETRY OF THE SODIUM PUMP-PHOSPHOLEMMAN REGULATORY COMPLEX
Seflova, J.; Habibi, N. R.; Yap, J. Q.; Cleary, S. R.; Fang, X.; Kekenes-Huskey, P. M.; Espinoza-Fonseca, L. M.; Bossuyt, J. B.; Robia, S. L.
10.1101/2021.10.12.464104 — biophysics — Posted on 2021-10-13
2546 Realization of phosphorylation hypothesis of sleep by mammalian CaMKIIβ
Ueda, H. R.; Tone, D.; Ode, K. L.; Zhang, Q.; Fujishima, H.; Yamada, R. G.; Nagashima, Y.; Matsumoto, K.; Wen, Z.; Yoshida, S. Y.; Mitani, T. T.; Ohno, R.-i.; Ukai-Tadenuma, M.; Garcon, J. Y.; Kaneko, M.; Shi, S.; Ukai, H.; Miyamichi, K.; Okada, T.; Sumiyama, K.; Kiyonari, H.
10.1101/2021.10.11.463945 — neuroscience — Posted on 2021-10-13
2554 phylogatR: Phylogeographic data aggregation and repurposing
Pelletier, T. A.; Parsons, D.; Decker, S.; Crouch, S.; Franz, E.; Ohrstrom, J.; Carstens, B. C.
10.1101/2021.10.11.461680 — bioinformatics — Posted on 2021-10-13
2557 Transcriptome-wide Association Study and eQTL colocalization identify potentially causal genes responsible for bone mineral density GWAS associations
Al-Barghouthi, B. M.; Rosenow, W. T.; Du, K.-P.; Heo, J.; Maynard, R.; Mesner, L.; Calabrese, G.; Nakasone, A.; Senwar, B.; Gerstenfeld, L.; Ferguson, V.; Ackert-Bicknell, C.; Morgan, E.; Brautigan, D. L.; Farber, C. R.
10.1101/2021.10.12.464046 — genomics — Posted on 2021-10-13
2560 Lifespan prolonging mechanisms and insulin upregulation without fat accumulation in long-lived reproductives of a higher termite
Seite, S.; Harrison, M. C.; Sillam-Dusses, D.; Lupoli, R.; Van Dooren, T. J. M.; Robert, A.; Poissonnier, L.-A.; Lemainque, A.; Renault, D.; Acket, S.; Andrieu, M.; Viscarra, J.; Sul, H. S.; de Beer, Z. W.; Bornberg-Bauer, E.; Vasseur-Cognet, M.
10.1101/2021.05.10.443390 — molecular biology — Posted on 2021-10-13
2561 White matter microstructural and morphometric alterations in autism: Implications for intellectual and verbal capabilities
Yeh, C.-H.; Tseng, R.-Y.; Ni, H.-C.; Cocchi, L.; Chang, J.-C.; Hsu, M.-Y.; Tu, E.-N.; Wu, Y.-Y.; Chou, T.-L.; Gau, S. S.-F.; Lin, H.-Y.
10.1101/2021.10.11.464005 — neuroscience — Posted on 2021-10-13
2563 Representations of temporal community structure in hippocampus and precuneus predict inductive reasoning decisions
Pudhiyidath, A.; Morton, N. W.; Viveros Duran, R.; Schapiro, A. C.; Momennejad, I.; Hinojosa-Rowland, D. M.; Molitor, R. J.; Preston, A. R.
10.1101/2021.10.12.462707 — neuroscience — Posted on 2021-10-13
2564 Hippocampus-striatum wiring diagram revealed by directed stepwise polysynaptic tracing
Du, W.; Li, E.; Guo, J.; Chen, Y.-t.; Oh, S. J.; Samuel, A.; Li, Y.; Oyibo, H. K.; Xu, W.
10.1101/2021.10.12.464132 — neuroscience — Posted on 2021-10-13
2567 Shorter constant work rate cycling tests as proxies for longer tests in highly trained cyclists
du Plessis, C.; Andrews, M.; Mitchell, L.; Cochrane Wilkie, J.; King, T.; Blazevich, A.
10.1101/2021.10.12.464126 — physiology — Posted on 2021-10-12
2570 Applying And Promoting Open Science In Ecology - Surveyed Drivers And Challenges
Stromme, C. B.; Lane, A. K.; Halbritter, A. H.; Law, E.; Nater, C. R.; Nilsen, E. B.; Boutouli, G. D.; Egelkraut, D. D.; Telford, R. J.; Vandvik, V.; Cotner, S. H.
10.1101/2021.10.12.464125 — scientific communication and education — Posted on 2021-10-12
2572 Rapid carbon accumulation at a saltmarsh restored by managed realignment far exceeds carbon emitted in site construction
Mossman, H. L.; Pontee, N.; Born, K.; Lawrence, P. J.; Rae, S.; Scott, J.; Serato, B.; Sparkes, R. B.; Sullivan, M. J. P.; Dunk, R. M.
10.1101/2021.10.12.464124 — ecology — Posted on 2021-10-12
2573 Stimulating music supports attention in listeners with attentional difficulties
Woods, K. J.; Sempaio, G.; James, T.; Przysinda, E.; Hewett, A.; Spencer, A. E.; Morillon, B.; Loui, P.
10.1101/2021.10.01.462777 — neuroscience — Posted on 2021-10-12
2574 Two faces of perceptual awareness during the attentional blink: Gradual and discrete
Karabay, A.; Wilhelm, S. A.; de Jong, J.; Wang, J.; Martens, S.; Akyurek, E. G.
10.1101/769083 — neuroscience — Posted on 2021-10-12
2575 Reassessing face topography in primary somatosensory cortex and remapping following hand loss
Root, V.; Muret, D.; Arribas, M.; Amoruso, E.; Thornton, J.; Tarall-Jozwiak, A.; Tracey, I.; Makin, T.
10.1101/2021.07.05.451126 — neuroscience — Posted on 2021-10-12
2576 The NUCKS1-SKP2-p21/p27 axis controls S phase entry
Hume, S.; Grou, C. P.; Lascaux, P.; D'Angiolella, V.; Legrand, A. J.; Ramadan, K.; Dianov, G. L.
10.1101/2021.06.29.450420 — cancer biology — Posted on 2021-10-12
2587 APOBEC mutagenesis is low in most types of non-B DNA structures, unlike other types of cancer mutagenesis
Ponomarev, G. V.; Fatykhov, B.; Nazarov, V. A.; Abasov, R.; Shvarov, E.; Landik, N.-V.; Denisova, A. A.; Chervova, A. A.; Gelfand, M. S.; Kazanov, M. D.
10.1101/2021.10.12.464135 — cancer biology — Posted on 2021-10-12
2588 Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action
Trifan, A.; Gorgun, D.; Li, Z.; Brace, A.; Zvyagin, M.; Ma, H.; Clyde, A. R.; Clark, D. A.; Salim, M.; Hardy, D.; Burnley, T.; Huang, L.; McCalpin, J.; Emani, M.; Yoo, H.; Yin, J.; Tsaris, A.; Subbiah, V.; Liu, J.; Trebesch, N.; Wells, G.; Mysore, V.; Gibbs, T.; Phillips, J.; Chennubhotla, S. C.; Foster, I.; Stevens, R.; Anandkumar, A.; Vishwanath, V.; Stone, J. E.; Tajkhorshid, E.; Harris, S. A.; Ramanathan, A.
10.1101/2021.10.09.463779 — biophysics — Posted on 2021-10-12
2590 Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1
Jones, A. N.; Grass, C.; Meininger, I.; Geerlof, A.; Klostermann, M.; Zarnack, K.; Krappmann, D.; Sattler, M.
10.1101/2021.10.12.464102 — biochemistry — Posted on 2021-10-12
2596 Early postnatal activation of the hypoxia pathway disrupts β-cell function
Yang, J.; Hammoud, B.; Ridler, A.; Won, K.-J.; Hoshi, T.; Stanley, C. A.; Stanescu, D. E.; Ackermann, A. M.
10.1101/2021.06.09.447705 — developmental biology — Posted on 2021-10-12
2597 Aged human iPSC-RPE organoid cultures display hallmarks of drusen formation
Mesch, L.; Pashkovskaia, N.; Cora, V.; Pars, S.; Corti, S.; Cipriano, M.; Loskill, P.; Koertvely, E.; Kustermann, S.; Mesquida, M.; Kleger, A.; Liebau, S.; Achberger, K.
10.1101/2021.10.12.463899 — cell biology — Posted on 2021-10-12
2598 gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes
Liu, N.; Lin, Y.; Li, L.; Lu, J.; Geng, D.; Zhang, J.; Jashashvili, T.; Buser, Z.; Magallanes, J.; Tassey, J.; Shkhyan, R.; Sarkar, A.; Lopez, N.; Wang, L.; Petrigliano, F.; Van Handel, B.; Lyons, K. M.; Evseenko, D.
10.1101/2021.10.12.464120 — cell biology — Posted on 2021-10-12
2599 A bacterial Argonaute with efficient DNA and RNA cleavage activity guided by small DNA and RNA
Ma, L.; wang, l.; Wang, F.; Xie, X.; Liu, Y.; Li, W.; Lv, B.; Zhang, Z.; Yang, J.; Yan, G.; Chen, W.; Zhang, C.
10.1101/2021.10.11.464003 — molecular biology — Posted on 2021-10-12
2601 An ancestral interaction module promotes oligomerisation in divergent mitochondrial ATP synthases
Gahura, O.; Muhleip, A.; Hierro-Yap, C.; Panicucci, B.; Jain, M.; Slapnickova, M.; Amunts, A.; Zikova, A.
10.1101/2021.10.10.463820 — molecular biology — Posted on 2021-10-12
2604 Macrophage Innate Training Induced by IL-4 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses
Lundahl, M. L.; Mitermite, M.; Ryan, D. G.; Williams, N. C.; Yang, M.; Lebre, F. M.; Gorman, A. L.; Stojkovic, B.; Frezza, C.; Scanlan, E. M.; O'Neill, L. A.; Gordon, S. V.; Lavelle, E. C.
10.1101/2021.10.12.463833 — immunology — Posted on 2021-10-12
2605 Dietary Proanthocyanidins Exert Localized Immunomodulatory Effects in Porcine Pulmonary and Gastrointestinal Tissues during Ascaris suum-induced Type 2 inflammation
Andersen-Civil, A. I. S.; Myhill, L. J.; Gokgoz, N. B.; Engstrom, M. T.; Mejer, H.; Zeller, W. E.; Salminen, J.-P.; Krych, L.; Lauridsen, C.; Nielsen, D. S.; Thamsborg, S. M.; Williams, A. R.
10.1101/2021.10.12.464117 — immunology — Posted on 2021-10-12
2606 Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion
Chen, F.; El-Naccache, D. W.; Ponessa, J. J.; Lemenze, A.; Espinosa, V.; Wu, W.; Lothstein, K.; Jin, L.; Antao, O.; Weinstein, J. S.; Damani-Yokota, P.; Khanna, K.; Murray, P. J.; Rivera, A.; Siracusa, M. C.; Gause, W. C.
10.1101/2020.10.02.322388 — immunology — Posted on 2021-10-12
2608 Single-particle cryo-EM structures from iDPC-STEM at near-atomic resolution
Lazic, I.; Wirix, M.; Leidl, M. L.; Haas, F. d.; Beckers, M.; Pechnikova, E. V.; Mueller-Caspary, K.; Egoavil, R.; Bosch, E. G. T.; Sachse, C.
10.1101/2021.10.12.464113 — biophysics — Posted on 2021-10-12
2609 Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
Van Ravenstein, S. X.; Mehta, K. P.; Kavlashvili, T.; Byl, J. A.; Zhao, R.; Osheroff, N.; Cortez, D.; Dewar, J. M.
10.1101/2021.10.12.464107 — biochemistry — Posted on 2021-10-12
2614 Ferroptosis Regulation by the NGLY1/NFE2L1 Pathway
Forcina, G. C.; Pope, L.; Murray, M.; Dong, W.; Abu-Remaileh, M.; Bertozzi, C. R.; Dixon, S. J.
10.1101/2021.10.12.463965 — cell biology — Posted on 2021-10-12
2615 The neurodevelopmental disorder-linked PHF14 complex that forms biomolecular condensates detects DNA damage and promotes repair
Käsper, E.-L.; Hwang, I.-Y.; Grötsch, H.; Fung, K. H. H.; Serandour, A. A.; Arecco, N.; Oellers, R.; Polinski, P.; Garcia Gomez-Monedero, A.; Müller, C. W.; Noh, K.-M.
10.1101/2021.10.12.462922 — molecular biology — Posted on 2021-10-12
2616 Locus-Specific DNA Methylation Editing in Mammalian Cells using a CRISPR-Based System
Smith, J.; Banerjee, R.; Waly, R.; Urbano, A.; Gimenez, G.; Day, R. C.; Eccles, M.; Weeks, R. J.; Chatterjee, A.
10.1101/2021.10.12.463855 — molecular biology — Posted on 2021-10-12
2617 SLX4 dampens MutSα-dependent mismatch repair
Guervilly, J.-H.; Blin, M.; Laureti, L.; Baudelet, E.; Audebert, S.; Gaillard, P.-H. L.
10.1101/2021.10.12.464076 — molecular biology — Posted on 2021-10-12
2618 Highly resolved spatial transcriptomics for detection of rare events in cells
Groiss, S.; Pabst, D.; Faber, C.; Meier, A.; Bogdoll, A.; Unger, C.; Nilges, B.; Strauss, S.; Foederl-Hoebenreich, E.; Hardt, M.; Geipel, A.; Reinecke, F.; Korfhage, C.; Zatloukal, K.
10.1101/2021.10.11.463936 — molecular biology — Posted on 2021-10-12
2619 Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner
Fernandez-Justel, J. M.; Santa-Maria, C.; Ferrera-Lagoa, A.; Salinas-Pena, M.; Maslon, M. M.; Jordan, A.; Caceres, J. F.; Gomez, M.
10.1101/2021.10.12.464039 — molecular biology — Posted on 2021-10-12
2620 Conserved α-helix-3 is crucial for structure and functions of Rad6 E2 ubiquitin-conjugating enzymes.
Shukla, P. K.; Sinha, D.; Leng, A. M.; Bissell, J. E.; Thatipamula, S.; Ganguly, R.; Skalicky, J. J.; Shrieve, D. C.; Chandrasekharan, M.
10.1101/2021.10.12.464121 — molecular biology — Posted on 2021-10-12
2623 New from old: discovery of the novel antibiotic actinomycin L in Streptomyces sp. MBT27
Machushynets, N.; Elsayed, S. S.; Du, C.; Siegler, M. A.; de la Cruz, M.; Genilloud, O.; Hankemeier, T.; van Wezel, G. P.
10.1101/2021.10.12.464064 — microbiology — Posted on 2021-10-12
2625 The Evolution of Host Specialization in an Insect Pathogen
Visher, E.; Uricchio, L.; Bartlett, L.; DeNamur, N.; Yarcan, A.; Alhassani, D.; Boots, M.
10.1101/2021.10.11.463986 — evolutionary biology — Posted on 2021-10-12
2626 SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids
Menuchin-Lasowski, Y.; Schreiber, A.; Lecanda, A.; Mecate-Zambrano, A.; Brunotte, L.; Psathaki, O. E.; Ludwig, S.; Rauen, T.; Schoeler, H. R.
10.1101/2021.10.09.463766 — molecular biology — Posted on 2021-10-12
2627 Thalamic activity during scalp slow waves in humans
Peter, U. P.; Szalardy, O.; Fabo, D.; Eross, L.; Bodizs, R.
10.1101/2021.10.11.463988 — neuroscience — Posted on 2021-10-12
2628 MicroPET evidence for a hypersensitive neuroinflammatory profile of gp120 mouse model of HIV
Young, J. W.; Barback, C. V.; Stolz, L. A.; Groman, S. M.; Vera, D. R.; Hoh, C.; Kotta, K. K.; Minassian, A.; Powell, S. B.; Brody, A. L.
10.1101/2021.10.11.463989 — neuroscience — Posted on 2021-10-12
2630 A functionally conserved STORR gene fusion in Papaver species that diverged 16.8 million years ago
Catania, T.; Li, Y.; Winzer, T.; Harvey, D.; Meade, F.; Caridi, A.; Larson, T. R.; Ning, Z.; Graham, I. A.
10.1101/2021.10.11.463683 — plant biology — Posted on 2021-10-12
2632 Coincident Fluorescence Burst Analysis of dUTP-Loaded Exosome-Mimetic Nanovesicles
Sanaee, M.; Sandberg, E.; Ronquist, G.; Morrell, J.; Widengren, J.; Gallo, K.
10.1101/2021.10.11.463914 — biophysics — Posted on 2021-10-12
2637 An extremes of phenotype approach confirms significant genetic heterogeneity in patients with ulcerative colitis.
Radford-Smith, G.; Mortlock, S.; Lord, A.; Montgomery, G.; Zakrzewski, M.; Simms, L. A.; Krishnaprasad, K.; Hanigan, K.; Doecke, J. D.; Walsh, A.; Lawrance, I.; Bampton, P. A.; Andrews, J. M.; Mahy, G.; Connor, S.; Sparrow, M.; Bell, S.; Florin, T.; Begun, J.; Gearry, R.
10.1101/2021.10.04.462982 — genetics — Posted on 2021-10-12
2638 Local adaptation and spatiotemporal patterns of genetic diversity revealed by repeated sampling of Caenorhabditis elegans across the Hawaiian Islands
Crombie, T. A.; Battlay, P.; Tanny, R. E.; Evans, K. S.; Buchanan, C. M.; Cook, D. E.; Dilks, C. M.; Stinson, L. A.; Zdraljevic, S.; Zhang, G.; Roberto, N. M.; Lee, D.; Ailion, M.; Hodgins, K. A.; Andersen, E. C.
10.1101/2021.10.11.463952 — ecology — Posted on 2021-10-12
2640 Investigating the growth of an engineered strain of Cyanobacteria with an Agent-Based Model and a Recurrent Neural Network
Sakkos, J.; Weaver, J.; Robertson, C.; Li, B.; Taniguchi, D.; Maheshwari, K.; Ducat, D.; Zuliani, P.; McGough, A. S.; Curtis, T. P.; Fuentes-Cabrera, M.
10.1101/2021.10.11.463942 — microbiology — Posted on 2021-10-12
2641 IL-1α secreted by subcapsular sinus macrophages promotes melanoma metastasis in the sentinel lymph node by upregulating STAT3 signaling in the tumor.
Virgilio, T.; Bordini, J.; Sartori, G.; Latino, I.; Molina-Romero, D.; Leoni, C.; Akhmedov, M.; Rinaldi, A.; Arribas, A. J.; Morone, D.; Jafari, S. M. S.; Bersudsky, M.; Ottolenghi, A.; Kwee, I.; Chiaravalli, A. M.; Sessa, F.; Hunger, R. E.; Bruno, A.; Mortara, L.; Voronov, E.; Monticelli, S.; Apte, R. N.; Bertoni, F.; F. Gonzalez, S.
10.1101/2021.10.11.463954 — immunology — Posted on 2021-10-12
2647 Application of synthetic peptide CEP1 increases nutrient uptake rates along plant roots
Roy, S.; Griffiths, M.; Torres-Jerez, I.; Sanchez, B.; Antonelli, E.; Jain, D.; Krom, N.; Zhang, S.; York, L. M.; Scheible, W.-R.; Udvardi, M.
10.1101/2021.10.11.463963 — plant biology — Posted on 2021-10-12
2648 CsMYB4a from Camellia sinensis Regulates the Auxin Signaling Pathway by Interacting with CsIAA4
Ma, G.; Wu, Y.; Jiang, C.; Chen, Y.; Xing, D.; Zhao, Y.; Liu, Y.; Xia, T.; Gao, L.
10.1101/2021.10.11.463959 — physiology — Posted on 2021-10-12
2649 Glucocorticoid signaling delays castration-induced regression in murine models of prostate cancer
Maolake, A.; Zhang, R.; Sha, K.; Singh, S.; Pan, C.; Xu, B.; Chatta, G.; Mastri, M.; Eng, K. H.; Nastiuk, K. L.; Krolewski, J. J.
10.1101/2021.10.11.463722 — cancer biology — Posted on 2021-10-12
2651 The BrightEyes-TTM: an Open-Source Time-Tagging Module for Single-Photon Microscopy
Rossetta, A.; Slenders, E.; Donato, M.; Perego, E.; Diotalevi, F.; Lanzano', L.; Koho, S. V.; Tortarolo, G.; Crepaldi, M.; Vicidomini, G.
10.1101/2021.10.11.463950 — bioengineering — Posted on 2021-10-12
2654 Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder
Waldron, S.; Pass, R.; Griesius, S.; Mellor, J. R.; Robinson, E. S. J.; Thomas, K. L.; Wilkinson, L. S.; Humby, T.; Hall, J.; Dwyer, D. M.
10.1101/2021.10.11.463943 — genetics — Posted on 2021-10-12
2656 Dormant replication origin firing links replication stress to whole chromosomal instability in human cancer
Schmidt, A.-K.; Boehly, N.; Zhang, X.; Slusarenko, B. O.; Hennecke, M.; Kschischo, M.; Bastians, H.
10.1101/2021.10.11.463929 — cell biology — Posted on 2021-10-12
2658 Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons
Hao, J.; Wells, M. F.; Niu, G.; Juan, I. G. S.; Limone, F.; Fukuda, A.; Leyton-Jaimes, M. F.; Joseph, B.; Qian, M.; Mordes, D. A.; Budnik, B.; Dou, Z.; Eggan, K.
10.1101/2021.10.11.464011 — neuroscience — Posted on 2021-10-12
2660 Annotation of glycolysis, gluconeogenesis, and trehaloneogenesis pathways provide insight into carbohydrate metabolism in the Asian citrus psyllid
Tamayo, B.; Kercher, K.; Vosburg, C.; Massimino, C.; Jernigan, M. R.; Hasan, D. L.; Harper, D.; Mathew, A.; Adkins, S.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Panitz, N.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; Delia, T.; Saha, S.
10.1101/2021.10.11.463922 — bioinformatics — Posted on 2021-10-12
2664 TRAIP regulates DNA double-strand break-induced ATM activation
Gleich, T.; Quadroni, M.; Yigit, G.; Wollnik, B.; Huber, M.; Pich Bavastro, C.; Hohl, D.
10.1101/2021.10.11.462297 — cell biology — Posted on 2021-10-12
2665 Rhythmicity of Intestinal IgA Responses Confers Oscillatory Commensal Microbiota Mutualism
Penny, H. A.; Domingues, R. G.; Krauss, M. Z.; Melo-Gonzalez, F.; Dickson, S.; Parkinson, J.; Hurry, M.; Purse, C.; Jegham, E.; Godinho-Silva, C.; Rendas, M.; Veiga-Fernandes, H.; Bechtold, D.; Grencis, R. K.; Toellner, K.-M.; Waisman, A.; Swann, J. R.; Gibbs, J. E.; Hepworth, M. R.
10.1101/2021.10.11.463908 — immunology — Posted on 2021-10-12
2667 Astrocytes derived from ASD patients alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling
Colak, D.; Allen, M.; Huang, B. S.; Notaras, M. J.; Lodhi, A.; Barrio-Alonso, E.; Wolujewicz, P.; Witztum, J.; Longo, F.; Chen, M.; Greening, D.; Klann, E.; Ross, M. E.; Liston, C.
10.1101/2021.10.11.463231 — neuroscience — Posted on 2021-10-12
2668 Structural Diversity of Photoswitchable Sphingolipids for Optodynamic Control of Lipid Raft Microdomains
Hartrampf, N.; Leitao, S. M.; Winter, N.; Toombs-Ruane, H.; Frank, J. A.; Schwille, P.; Trauner, D.; Franquelim, H. G.
10.1101/2021.10.11.463883 — biophysics — Posted on 2021-10-12
2670 PeakBot: Machine learning based chromatographic peak picking
Bueschl, C.; Doppler, M.; Varga, E.; Seidl, B.; Flasch, M.; Zanghellini, J.
10.1101/2021.10.11.463887 — bioinformatics — Posted on 2021-10-12
2672 Antibacterial 3D-printed PMMA/ceramic composites
Marin, E.; Mukai, M.; Boschetto, F.; Sunthar, T. P. M.; Adachi, T.; Zhu, W.; Rondinella, A.; Lanzutti, A.; Kanamura, N.; Yamamoto, T.; Fedrizzi, L.; Pezzotti, G.
10.1101/2021.10.11.463892 — bioengineering — Posted on 2021-10-12
2674 Hydrophobicity in clearwing butterflies and moths: impact of scale 2 micro and nanostructure, and trade-off with optical transparency
Gomez, D.; Pairraire, J.; Pinna, C.; Arias, M.; Houssin, C.; Barbut, J.; Berthier, S.; Andraud, C.; Ondarcuhu, T.; Elias, M.
10.1101/2021.10.11.463886 — evolutionary biology — Posted on 2021-10-12
2677 Climate shapes flowering periods across plant communities
Stephens, R. E.; Sauquet, H.; Guerin, G. R.; Jiang, M.; Falster, D. S.; Gallagher, R. V.
10.1101/2021.10.10.463841 — ecology — Posted on 2021-10-12
2680 FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis
Wang, F.; Xu, S.; Chen, T.; Ling, S.; Zhang, W.; Wang, S.; Zhou, R.; Xia, X.; Yao, Z.; Li, P.; Zhao, X.; Wang, J.; Guo, X.
10.1101/2021.10.11.463898 — cell biology — Posted on 2021-10-12
2681 C9orf72-derived poly-GA DPRs undergo endocytic uptake in iNPC-derived astrocytes and spread to motor neurons
Marchi, P. M.; Marrone, L.; Brasseur, L.; Bousset, L.; Webster, C. P.; Destro, M.; Walther, C. G.; Alfred, V.; Marroccella, R.; Robinson, D.; Shaw, A. C.; Wan, L. M.; Grierson, A.; Ebbens, S. J.; Hautbergue, G. M.; Ferraiuolo, L.; Melki, R.; Azzouz, M.
10.1101/2021.10.11.463891 — neuroscience — Posted on 2021-10-12
2682 Additive, synergic and antagonistic interactions between maternal immune activation and peripubertal stress in cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome.
Capellan, R.; Orihuel, J.; Marcos, A.; Moreno-Fernandez, M.; Casquero-Veiga, M.; Soto-Montenegro, M. L.; Desco, M.; Oteo-Vives, M.; Ibanez-Moragues, M.; Magro-Calvo, N.; Morcillo, M. A.; Ambrosio, E.; Higuera-Matas, A.
10.1101/2021.10.11.463760 — neuroscience — Posted on 2021-10-12
2687 Elevated transcriptional pausing of RNA polymerase II underlies acquired resistance to radiotherapy
Liu, H.; Yu, C.; Zhang, N.; Meng, Y.; Huang, C.; Hu, C.; Chen, F.; Xiao, Z.; Zhang, Z.; Shao, H.; Yuan, K.
10.1101/2021.10.11.462362 — cancer biology — Posted on 2021-10-12
2692 Deep learning redesign of PETase for practical PET degrading applications
Lu, H.; Diaz, D. J.; Czarnecki, N. J.; Zhu, C. J.; Kim, W.; Acosta, D. J.; Alexander, B.; Shroff, R.; Cole, H.; Zhang, Y. J.; Lynd, N.; Ellington, A. D.; Alper, H. S.
10.1101/2021.10.10.463845 — bioengineering — Posted on 2021-10-12
2696 Effects of forest disturbance and regeneration on tree species composition and traits in DR Congo
Depecker, J.; Asimonyio, J. A.; Miteho, R.; Hatangi, Y.; Kambale, J.-L.; Verleysen, L.; Stoffelen, P.; Janssens, S.; Dhed'a, B.; Vandelook, F.; Honnay, O.
10.1101/2021.10.11.463162 — ecology — Posted on 2021-10-12
2702 Decoding of human identity by computer vision and neuronal vision
Zhang, Y.; M. Aghajan, Z.; Ison, M.; Lu, Q.; Tang, H.; Kalender, G.; Monsoor, T.; Zheng, J.; Kreiman, G.; Roychowdhury, V.; Fried, I.
10.1101/2021.10.10.463839 — neuroscience — Posted on 2021-10-12
2707 Multiparametric Platform for Profiling Lipid Trafficking in Human Leukocytes: Application for Hypercholesterolemia
Pfisterer, S. G.; Brock, I.; Kanerva, K.; Hlushchenko, I.; Paavolainen, L.; Ripatti, P.; Islam, M. M.; Kyttala, A.; Di Taranto, M. D.; di Frega, A. S.; Fortunato, G.; Kuusisto, J.; Horvath, P.; Ripatti, S.; Laakso, M.; Ikonen, E.
10.1101/2021.04.19.440471 — cell biology — Posted on 2021-10-12
2708 Rat sensitivity to multipoint statistics is predicted by efficient coding of natural scenes
Caramellino, R.; Piasini, E.; Buccellato, A.; Carboncino, A.; Balasubramanian, V.; Zoccolan, D.
10.1101/2021.05.17.444510 — neuroscience — Posted on 2021-10-12
2710 Brain Data Standards Ontology: A data-driven ontology of transcriptomically defined cell types in the primary motor cortex
Tan, S. Z. K.; Kir, H.; Aevermann, B.; Gillespie, T.; Hawrylycz, M.; Lein, E.; Matentzoglu, N.; Miller, J. A.; Mollenkopf, T. S.; Mungall, C. J.; Ray, P. L.; Sanchez, R. E. A.; Scheuermann, R. H.; Staats, B.; Yadav, A.; Zhang, Y. H.; Osumi-Sutherland, D.
10.1101/2021.10.10.463703 — neuroscience — Posted on 2021-10-12
2713 Whole genome sequence analysis of blood lipid levels in >66,000 individuals
Selvaraj, M. S.; Li, X.; Li, Z.; Pampana, A.; Zhang, D. Y.; Park, J.; Aslibekyan, S.; Bis, J. C.; Brody, J. A.; Cade, B. E.; Chuang, L.-M.; Chung, R.-H.; Curran, J. E.; de las Fuentes, L.; de Vries, P. S.; Duggirala, R.; Freedman, B. I.; Graff, M.; Guo, X.; Heard-Costa, N.; Hidalgo, B.; Hwu, C.-M.; Irvin, M. R.; Kelly, T. N.; Kral, B. G.; Lange, L.; Li, X.; Lisa, M.; Lubitz, S. A.; Manichaikul, A. W.; Michael, P.; Montasser, M. E.; Morrison, A. C.; Naseri, T.; O'Connell, J. R.; Palmer, N. D.; Peyser, P. A.; Reupena, M. S.; Smith, J. A.; Sun, X.; Taylor, K. D.; Tracy, R. P.; Tsai, M. Y.; Wang,
10.1101/2021.10.11.463514 — genetics — Posted on 2021-10-12
2715 Model-based ordination with constrained latent variables
Veen, B. v. d.; Hui, F. K. C.; Hovstad, K. A.; O'Hara, R. B.
10.1101/2021.10.11.463884 — ecology — Posted on 2021-10-12
2717 HORmon: automated annotation of human centromeres
Kunyavskaya, O.; Dvorkina, T.; Bzikadze, A. V.; Alexandrov, I.; Pevzner, P. A.
10.1101/2021.10.12.464028 — bioinformatics — Posted on 2021-10-12
2719 A personalized network framework reveals predictive axis of anti-TNF response across diseases
Gerassy-Vainberg, S.; Starosvetsky, E.; Gaujoux, R.; Blatt, A.; Maimon, N.; Gorelik, Y.; Pressman, S.; Alpert, A.; Bar-Yoseph, H.; Dubovik, T.; Perets, B.; Katz, A.; Milman, N.; Chowers, Y.; Shen-Orr, S. S.
10.1101/2021.06.16.448558 — systems biology — Posted on 2021-10-12
2720 Factorbook: an Updated Catalog of Transcription Factor Motifs and Candidate Regulatory Motif Sites
Pratt, H. E.; Andrews, G. R.; Phalke, N.; Purcaro, M. J.; van der Velde, A. G.; Moore, J. E.; Weng, Z.
10.1101/2021.10.11.463518 — bioinformatics — Posted on 2021-10-12
2724 Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development
Park, V. S.; Sun, M. J.; Frey, W. D.; Williams, L. G.; Hodel, K. P.; Strauss, J. D.; Wellens, S. J.; Jackson, J. G.; Pursell, Z. F.
10.1101/2021.10.10.463847 — cancer biology — Posted on 2021-10-12
2727 Getting more out of FLAG-Tag co-immunoprecipitation mass spectrometry experiments using FAIMS.
Ang, C.-S.; Sacharz, J.; Leeming, M. G.; Nie, S.; Varshney, S.; Scott, N. E.; Williamson, N. A.
10.1101/2021.06.15.448610 — biochemistry — Posted on 2021-10-11
2728 A curated collection of Klebsiella metabolic models reveals variable substrate usage and gene essentiality
Hawkey, J.; Vezina, B.; Monk, J.; Judd, L. M.; Harshegyi, T.; Lopez-Fernandez, S.; Rodrigues, C.; Brisse, S.; Holt, K. E.; Wyres, K. L.
10.1101/2021.10.10.463858 — microbiology — Posted on 2021-10-11
2730 Rare instances of non-random dropout with the monochrome multiplex qPCR assay for mitochondrial DNA copy number
Yang, S. Y.; Newcomb, C. E.; Battle, S. L.; Hsieh, A. Y.; Chapman, H. L.; Cote, H. C.; Arking, D. E.
10.1101/2021.10.11.463983 — genetics — Posted on 2021-10-11
2731 A Multi-proxy assessment of the impact of climate change on Late Holocene (ca 4500-3800 BP) Native American villages of the Georgia coast
Garland, C. J.; Thompson, V. D.; Sanger, M. C.; Smith, K. Y.; Andrus, F. T.; Lawres, N. R.; Napora, K. G.; Calaninno, C. E.; Compton, J. M.; Jones, S.; Hadden, C. S.; Cherkinsky, A.; Maddox, T.; Deng, Y.-t.; Lulewicz, I. H.; Parsons, L.
10.1101/2021.10.11.463980 — ecology — Posted on 2021-10-11
2732 Overexpression of the SETD2 WW domain inhibits the phosphor-IWS1/SETD2 interaction and the oncogenic AKT/IWS1 RNA splicing program.
Laliotis, G. I.; Chavdoula, E.; Anastas, V.; Singh, S.; Kenney, A. I.; Achaya, S.; Yount, J. S.; Sehgal, L.; Tsichlis, P. N.
10.1101/2021.08.12.454141 — cancer biology — Posted on 2021-10-11
2735 Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy
Georgiou, M.; Yang, C.; Atkinson, R.; Pan, K.-T.; Buskin, A.; Moya Molina, M.; Collin, J.; Al-Aama, J.; Goertler, F.; Ludwig, S. E. J.; Davey, T.; Luhrmann, R.; Nagaraja-Grellscheid, S.; Johnson, C.; Ali, R.; Armstrong, L.; Korolchuk, V.; Urlaub, H.; Mozaffari-Jovin, S.; Lako, M.
10.1101/2021.10.11.463925 — cell biology — Posted on 2021-10-11
2736 Catestatin selects for the colonization of antimicrobial-resistant gut bacterial communities
Gonzalez-Davila, P.; Schwalbe, M.; Danewalia, A.; Dalile, B.; Verbeke, K.; Mahata, S. K.; El Aidy, S.
10.1101/2021.10.11.463921 — microbiology — Posted on 2021-10-11
2737 Phage-encoded ribosomal protein S21 expression is linked to late stage phage replication
Chen, L.-X.; Jaffe, A. L.; Borges, A. L.; Penev, P.; Nelson, T. C.; Warren, L. A.; Banfield, J.
10.1101/2021.10.11.463225 — microbiology — Posted on 2021-10-11
2738 Multiple nutritional and gut microbial factors associated with allergic rhinitis: the Hitachi Health Study
Sahoyama, Y.; Hamazato, F.; Shiozawa, M.; Nakagawa, T.; Suda, W.; Ogata, Y.; Hachiya, T.; Kawakami, E.; Hattori, M.
10.1101/2021.10.11.463208 — microbiology — Posted on 2021-10-11
2739 Molecular assembly of measles and Nipah virus: specific lipid binding drives conformational change and matrix polymerization
Norris, M. J.; Husby, M. L.; Kiosses, W. B.; Yin, J.; Rennick, L. J.; Heiner, A.; Harkins, S. S.; Pokhrel, R.; Schendel, S. L.; Hastie, K. M.; Landeras-Bueno, S.; Li Salie, Z.; Lee, B.; Chapagain, P. P.; Maisner, A.; Duprex, W. P.; Stahelin, R. V.; Ollmann Saphire, E.
10.1101/2021.10.11.463969 — microbiology — Posted on 2021-10-11
2741 CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals
Li, Y.; Wu, Y.; Federzoni, E. A.; Wang, X.; Dharmawan, A.; Hu, X.; Wang, H.; Hawley, R. J.; Stevens, S.; Sykes, M.; Yang, Y.-G.
10.1101/2021.10.11.463903 — immunology — Posted on 2021-10-11
2743 Human photoreceptors switch from autonomous axon extension to cell-mediated process pulling during synaptic marker redistribution.
Rempel, S. K.; Welch, M. J.; Ludwig, A. L.; Phillips, M. J.; Kancherla, Y.; Zack, D.; Gamm, D. M.; Gomez, T. M.
10.1101/2021.10.10.463810 — neuroscience — Posted on 2021-10-11
2744 Probiotic-guided CAR-T cells for universal solid tumor targeting
Vincent, R. L.; Gurbatri, C.; Redenti, A.; Coker, C.; Arpaia, N.; Danino, T.
10.1101/2021.10.10.463366 — bioengineering — Posted on 2021-10-11
2746 Cyclic constrained immunoreactive peptides from crucial P. falciparum proteins: potential implications in malaria diagnostics
VASHISHT, K.; SRIVASTAVA, S.; KUMARI, V.; DAS, R.; SHARMA, S.; BHARDWAJ, N.; ANVIKAR, A. R.; KIM, T. S.; NA, B. K.; SHIN, H. J.; PANDEY, K. C.
10.1101/2021.10.11.463910 — biochemistry — Posted on 2021-10-11
2747 Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity
Foulkes, D. M.; McLean, K.; Sloniecka, M.; Byrne, D.; Haneef, A. S.; Winstanley, C.; Berry, N.; Fernig, D.; Kaye, S. B.
10.1101/2021.10.11.463927 — biochemistry — Posted on 2021-10-11
2748 Draft genomes of a male and female Australian jacky dragon (Amphibolurus muricatus)
Tian, R.; Guo, H.; Yang, C.; Fan, G.; Whiteley, S. L.; Holleley, C. E.; Seim, I.; Georges, A.
10.1101/2021.10.11.463868 — genomics — Posted on 2021-10-11
2749 Natural history of a mouse model of X-linked myotubular myopathy
Sarikaya, E.; Volpatti, J.; Sabha, N.; Maani, N.; Gonorazky, H. D.; Celik, A.; Onofre-Oliveira, P.; Dowling, J. J.
10.1101/2021.10.11.463940 — genetics — Posted on 2021-10-11
2751 Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs
Wu, X.; Zhang, H.; Zhang, B.; Zhang, Y.; Wang, Q.; Shen, W.; Wu, X.; Li, L.; Xia, W.; Nakamura, R.; Liu, B.; Liu, F.; Takeda, H.; Meng, A.; Xie, W.
10.1101/2021.10.10.463758 — developmental biology — Posted on 2021-10-11
2752 Fluorescence exclusion: a rapid, accurate and powerful method for measuring yeast cell volume
Garcia-Ruano, D.; Jain, A.; Ryan, J. C.; Balasubramaniam, V. R.; Venkova, L.; Piel, M.; Coudreuse, D.
10.1101/2021.10.07.463508 — cell biology — Posted on 2021-10-11
2753 Dynamin-2 Phosphorylation as A Critical Regulatory Target of Bin1 and GSK3α for Endocytosis in Muscle
Laiman, J.; Loh, J.; Tang, W.-C.; Chuang, M.-C.; Liu, H.-K.; Chen, B.-C.; Chang, Y.-C.; Chuang, L.-M.; Liu, Y.-W.
10.1101/2021.10.11.463889 — cell biology — Posted on 2021-10-11
2754 Clock gene-independent daily regulation of haemoglobin oxidation in red blood cells
Beale, A. D.; Crosby, P.; Valekunja, U. K.; Edgar, R. S.; Chesham, J. E.; Maywood, E. S.; Labeed, F. H.; Reddy, A. B.; Wright, K. P.; Lilley, K. S.; Hastings, M. H.; O'Neill, J. S.
10.1101/2021.10.11.463714 — cell biology — Posted on 2021-10-11
2755 JIP3 regulates bi-directional organelle transport in neurons through its interaction with dynein and kinesin-1
Celestino, R.; Gama, J. B.; Castro-Rodrigues, A. F.; Barbosa, D. J.; d'Amico, E. A.; Musacchio, A.; Xavier de Carvalho, A.; Morais-Cabral, J. H.; Gassmann, R.
10.1101/2021.10.11.463801 — cell biology — Posted on 2021-10-11
2756 Genome-edited zebrafish model of ABCC8 loss-of-function disease
Ikle, J. M.; Tryon, R. C.; Singareddy, S. S.; York, N. W.; Remedi, M. S.; Nichols, C. G.
10.1101/2021.10.10.461291 — cell biology — Posted on 2021-10-11
2757 Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter
Schmitt, D. L.; Curtis, S. D.; Leung, A.; Zhang, J.-f.; Chen, M.; He, C. Y.; Mehta, S.; Rangamani, P.; Shaw, R. J.; Zhang, J.
10.1101/2021.10.11.463987 — molecular biology — Posted on 2021-10-11
2758 HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex
Leisegang, M. S.; Kaur Bains, J.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Sentuerk Cetin, N.; Warwick, T.; Cao, C.; Boos, F.; Izquierdo Ponce, J.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D.; Preussner, J. S.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.
10.1101/2021.10.11.463905 — molecular biology — Posted on 2021-10-11
2759 Serine/arginine-rich splicing factor 7 plays oncogenic roles through specific regulation of m6A RNA modification
Cun, Y.; An, S.; Zheng, H.; Lan, J.; Chen, W.; Luo, W.; Yao, C.; Li, X.; Huang, X.; Sun, X.; Wu, Z.; Hu, Y.; Li, Z.; Zhang, S.; Wu, G.; Yang, M.; Tang, M.; Yu, R.; Liao, X.; Gao, G.; Zhao, W.; Wang, J.; Li, J.
10.1101/2021.10.11.463901 — molecular biology — Posted on 2021-10-11
2760 Short-Term Dairy Elimination and Reintroduction Minimally Perturbs the Gut Microbiota in Self-Reported Lactose Intolerant Adults
Smith, C. J.; Dethlefsen, L.; Gardner, C.; Nguyen, L.; Feldman, M.; Costello, E. K.; Kolodny, O.; Relman, D. A.
10.1101/2021.10.10.463842 — microbiology — Posted on 2021-10-11
2761 Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation .
Lemberg, C.; Martinez de San Vicente, K.; Frois-Martins, R.; Altmeier, S.; Tran, V. D. T.; Amorim-Vaz, S.; Rai, L.; d'Enfert, C.; Pagni, M.; Sangalrd, D.; LeibundGut-Landmann, S.
10.1101/2021.10.11.463879 — microbiology — Posted on 2021-10-11
2764 Nipah virus Bangladesh infection elicits organ-specific innate and inflammatory responses in the marmoset model
Stevens, C. S.; Lowry, J.; Juelich, T.; Atkins, C.; Johnson, K.; Smith, J. K.; Panis, M.; Ikegame, T.; tenOever, B.; Freiberg, A. N.; Lee, B.
10.1101/2021.10.11.463955 — microbiology — Posted on 2021-10-11
2767 The AMIGO1 adhesion protein activates Kv2.1 voltage sensors
Sepela, R. J.; Stewart, R. G.; Valencia, L.; Thapa, P.; Wang, Z.; Cohen, B. E.; Sack, J. T.
10.1101/2021.06.20.448455 — biophysics — Posted on 2021-10-11
2768 Annotation of Putative Circadian Rhythm-Associated Genes in Diaphorina citri (Hemiptera : Liviidae)
Reynolds, M.; de Oliveira, L.; Paris, T.; Vosburg, C.; Massimino, C.; Norus, J.; Ortiz, Y.; Espino, M.; Davis, N.; Masse, R.; Neiman, A.; Holcomb, R.; Gervais, K.; Kemp, M.; Hoang, M.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Benoit, J. B.; Brown, S. J.; Delia, T.; Saha, S.
10.1101/2021.10.09.463768 — bioinformatics — Posted on 2021-10-11
2770 Genome size evolution in the beetle genus Diabrotica
Lata, D.; Coates, B. S.; Walden, K. K. O.; Robertson, H. M.; Miller, N. J.
10.1101/2021.09.04.458993 — genomics — Posted on 2021-10-11
2771 ConVarT: a search engine for matching human genetic variants with variants from non-human species
Pir, M. S.; Bilgin, H. I.; Sayici, A.; Coskun, F.; Torun, F. M.; Zhao, P.; Kang, Y.; Cevik, S.; Kaplan, O. I.
10.1101/2021.01.07.424951 — genetics — Posted on 2021-10-11
2775 Immunity to SARS-CoV-2 up to 15 months after infection
Marcotte, H.; Piralla, A.; Zuo, F.; Du, L.; Cassaniti, I.; Wan, H.; Kumagai-Braesh, M.; Andrell, J.; Percivalle, E.; Sammartino, J. C.; Wang, Y.; Vlachiotis, S.; Attevall, J.; Bergami, F.; Ferrari, A.; Colaneri, M.; Vecchia, M.; Sambo, M.; Zuccaro, V.; Asperges, E.; Bruno, R.; Oggionni, T.; Meloni, F.; Abolhassanni, H.; Bertoglio, F.; Schubert, M.; Calzolai, L.; Varani, L.; Hust, M.; Xue, Y.; Hammarstrom, L.; Baldanti, F.; Pan-Hammarstrom, Q.
10.1101/2021.10.08.463699 — immunology — Posted on 2021-10-11
2776 The organization of the gravity-sensing system in zebrafish
Liu, Z.; Hildebrand, D. G. C.; Morgan, J. L.; Jia, Y.; Slimmon, N.; Bagnall, M. W.
10.1101/2021.07.09.451839 — neuroscience — Posted on 2021-10-11
2778 Patient-Derived Organoids Recapitulate Intrinsic Immune Landscapes and Progenitor Populations of Glioblastoma.
Watanabe, F.; Hollingsworth, E. W.; Bartley, J. M.; Wisehart, L.; Desai, R.; Hartlaub, A. M.; Hester, M. E.; Schiapparelli, P.; Hinojosa, A. Q.; Imitola, J.
10.1101/2021.10.06.463228 — neuroscience — Posted on 2021-10-11
2780 Fluorescence Activation Mechanism and Imaging of Drug Permeation with New Sensors for Smoking-Cessation Ligands
Nichols, A. L.; Blumenfeld, Z.; Fan, C.; Luebbert, L.; Blom, A. E. M.; Cohen, B. N.; Marvin, J. S.; Borden, P. M.; Kim, C.; Muthusamy, A. K.; Shivange, A. V.; Knox, H. J.; Campello, H. R.; Wang, J. H.; Dougherty, D. A.; Looger, L.; Gallagher, T.; Rees, D. C.; Lester, H. A.
10.1101/2021.10.04.463082 — pharmacology and toxicology — Posted on 2021-10-11
2782 Orthogonal CRISPR-Cas tools for genome editing, inhibition, and CRISPR recording in zebrafish embryos.
Takasugi, P. R.; Wang, S.; Truong, K. T.; Drage, E. P.; Kanishka, S. N.; Higbee, M. A.; Bamidele, N.; Ojelabi, O.; Sontheimer, E. J.; Gagnon, J. A.
10.1101/2020.11.07.372151 — genetics — Posted on 2021-10-11
2784 Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation
DAVID, L.; Taieb, F.; Penary, M.; Bordignon, P.-J.; Planes, R.; Bagayoko, S.; Duplan-Eche, V.; Meunier, E.; Oswald, E.
10.1101/2021.04.20.440604 — microbiology — Posted on 2021-10-11
2785 Predicting age and clinical risk from the neonatal connectome
Taoudi-Benchekroun, Y.; Christiaens, D.; Grigorescu, I.; Gale-Grant, O.; Schuh, A.; Pietsch, M.; Chew, A.; Harper, N.; Falconer, S.; Poppe, T.; Hughes, E.; Hutter, J.; Price, A. N.; Tournier, J.-D.; Cordero-Grande, L.; Counsell, S. J.; Rueckert, D.; Arichi, T.; Hajnal, J. V.; Edwards, A. D.; Deprez, M.; Batalle, D.
10.1101/2020.09.28.317180 — neuroscience — Posted on 2021-10-11
2786 Combining CRISPR/Cas9 and brain imaging: from genes to molecules to networks
Marciano, S.; Ionescu, T. M.; Saw, R. S.; Cheong, R. Y.; Kirik, D.; Maurer, A.; Pichler, B. J.; Herfert, K.
10.1101/2021.09.10.459766 — neuroscience — Posted on 2021-10-11
2791 High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain
Dasovich, M. A.; Zhuo, J.; Thomas, A. G.; Goodman, J. A.; McPherson, R. L.; Jayabalan, A. K.; Busa, V. F.; Cheng, S.-J.; Murphy, B.; Redinger, K. R.; Tsukamoto, T.; Slusher, B. S.; Bosch, J.; Wei, J.; Leung, A.
10.1101/2021.10.07.463234 — biochemistry — Posted on 2021-10-11
2792 Location and function of Plasmodium kinesins: key roles in parasite proliferation, polarity, and transmission
Zeeshan, M.; Rashpa, R.; Ferguson, D. J. P.; Abel, S.; Chahine, Z.; Brady, D.; vaughan, s.; Moores, C. A.; Le Roch, K. G.; Brochet, M.; Holder, A. A.; Tewari, R.
10.1101/2021.05.26.445751 — cell biology — Posted on 2021-10-11
2793 Effector membrane translocation biosensors reveal G protein and β-arrestin coupling profiles of 100 therapeutically relevant GPCRs
Avet, C.; Mancini, A.; Breton, B.; Le Gouill, C.; Hauser, A. S.; Normand, C.; Kobayashi, H.; Gross, F.; Hogue, M.; Lukasheva, V.; St-Onge, S.; Carrier, M.; Heroux, M.; Morissette, S.; Fauman, E.; Fortin, J.-P.; Schann, S.; Leroy, X.; Gloriam, D. E.; Bouvier, M.
10.1101/2020.04.20.052027 — pharmacology and toxicology — Posted on 2021-10-11
2795 Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA
Bartas, M.; Volna, A.; Beaudoin, C. A.; Poulsen, E. T.; Cerven, J.; Brazda, V.; Spunda, V.; Blundell, T. L.; Pecinka, P.
10.1101/2020.11.27.400788 — microbiology — Posted on 2021-10-11
2796 Immunogenicity of SARS-CoV-2 trimetric spike protein associated to Poly(I:C) plus Alum
Santos, J. d.; Cruz, L. F.; Fonseca-Martins, A. M. d.; Maciel, D. O.; Perez, G. G.; Roncaglia-Pereira, V. A.; Dumard, C. H.; Guedes da Silva, F. H.; dos Santos, A. C. V.; Leandro, M. S.; Ferreira, J. R. M.; Pinto, K. G.; Conde, L.; Rodrigues, D. A. S.; Silva, M. V. M.; Alvim, R. G. F.; Lima, T. M.; Marsili, F. F.; Abreu, D. P. B. d.; Ferreira, O. C.; Borges, R. d. S. M.; Tanuri, A.; Souza, T. M. L.; Rossi-Bergmann, B.; Vale, A. M.; Silva, J. L.; de Oliveira, A. C.; Filardy, A. A.; Gomes, A. M. O.; de Matos Guedes, H. L.
10.1101/2021.10.05.461434 — immunology — Posted on 2021-10-11
2798 Integrative COVID-19 Biological Network Inference with Probabilistic Core Decomposition
Guo, Y.; Esfahani, F.; Shao, X.; Srinivasan, V.; Thomo, A.; Xing, L.; Zhang, X.
10.1101/2021.06.23.449535 — bioinformatics — Posted on 2021-10-11
2799 Dynamics of synthetic yeast chromosome evolution shaped by hierarchical chromatin organization
Zhou, S.; Wu, Y.; zhao, Y.; Zhang, Z.; Jiang, L.; Liu, L.; Zhang, Y.; Tang, J.; Yuan, Y.-J.
10.1101/2021.07.19.453002 — synthetic biology — Posted on 2021-10-11
2805 Explicit expression of mesophyll conductance in the traditional leaf photosynthesis-transpiration coupled model and its physiological significances
Luo, H.; Carriqui, M.; Nadal, M.; Han, T.; Werner, C.; Huang, J.-f.; Zhang, J.-l.; Yu, Z.-g.; Li, F.-m.; Fang, X.-w.; Xue, W.
10.1101/2021.09.22.461327 — ecology — Posted on 2021-10-11
2809 Waning grasslands: a quantitative temporal evaluation of the grassland habitats across human-dominated upper Gangetic Plains, north India
Paul, S.; Saha, S.; Nigam, P.; Ali, S. Z.; Page, N.; Khan, A. S.; Kumar, M.; Habib, B.; Mohan, D.; Pandav, B.; Mondol, S.
10.1101/2021.10.10.463811 — ecology — Posted on 2021-10-11
2812 Novel players and large-scale protein dynamics of BCR activation revealed by APEX2 proximity labelling of lipid rafts
Awoniyi, L. O.; Runsala, M.; Hernandez-Perez, S.; Sustar, V.; Cunha, D. M.; Sarapulov, A. V.; Petrov, P.; Mattila, P. K.
10.1101/2020.09.29.318766 — immunology — Posted on 2021-10-10
2816 Breast tumor IGF-1R regulates cell adhesion and metastasis: Alignment of mouse single cell and human breast cancer transcriptomics
Obr, A. E.; Chang, Y.-J.; Ciliento, V.; Lemenze, A.; Maingrette, K.; Bulatowicz, J. J.; Shang, Q.; Gallagher, E.; LeRoith, D.; Wood, T. L.
10.1101/2021.08.31.458283 — cancer biology — Posted on 2021-10-10
2817 Epigenetic MRI: Noninvasive Imaging of DNA Methylation in the Brain
Lam, F.; Chu, J.; Choi, J. S.; Cao, C.; Hitchens, T. K.; Silverman, S. K.; Liang, Z.-P.; Dilger, R. N.; Robinson, G. E.; Li, K. C.
10.1101/2021.08.20.457113 — bioengineering — Posted on 2021-10-10
2818 High-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice provides novel insight on the impact of host genetics
Doms, S.; Fokt, H.; Ruehlemann, M. C.; Chung, C. J.; Kuenstner, A.; Ibrahim, S.; Franke, A.; Turner, L. M.; Baines, J. F.
10.1101/2021.09.28.462095 — genetics — Posted on 2021-10-10
2819 Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits - the Hispanic/Latino Anthropometry Consortium
Fernandez-Rhodes, L.; Graff, M.; Buchanan, V. L.; Justice, A. E.; Highland, H. M.; Guo, X.; Zhu, W.; Chen, H.-H.; Young, K. L.; Adhikari, K.; Allred, N. P.; Below, J. E.; Bradfield, J.; Pereira, A. C.; Glover, L.; Kim, D.; Lilly, A. G.; Shrestha, P.; Thomas, A. G.; Zhang, X.; Chen, M.; Chiang, C. W. K.; Pulit, S.; Horimoto, A.; Krieger, J. E.; Guindo-Martinez, M.; Preuss, M.; Schumann, C.; Smit, R. A. J.; Torres-Mejia, G.; Acuna-Alonzo, V.; Bedoya, G.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo, C.; Gonzalez-Jose, R.; Poletti, G.; Rothhammer, F.; Hakonarson, H.; Igo, R.; Adler, S. G.; Iy
10.1101/2021.05.27.445969 — genetics — Posted on 2021-10-10
2820 A Spatiotemporal Map of Reading Aloud
Woolnough, O.; Donos, C.; Curtis, A.; Rollo, P. S.; Roccaforte, Z. J.; Dehaene, S.; Fischer-Baum, S.; Tandon, N.
10.1101/2021.05.23.445307 — neuroscience — Posted on 2021-10-10
2821 BDNF signaling in Hebbian and Stentian structural plasticity in the developing visual system
Kutsarova, E.; Schohl, A.; Munz, M.; Wang, A.; Zhang, Y. Y.; Bilash, O. M.; Ruthazer, E. S.
10.1101/2021.10.07.463583 — neuroscience — Posted on 2021-10-10
2824 3D U-Net improves automatic brain extraction for isotropic rat brain MRI data
Hsu, L.; Wang, S.; Walton, L.; Wang, T.-W. W.; Lee, S.-H.; Shih, Y.-Y. I.
10.1101/2021.09.27.462020 — neuroscience — Posted on 2021-10-10
2825 Analysis and modeling of cancer drug responses using cell cycle phase-specific rate effects
Gross, S. M.; Mohammadi, F.; Sanchez-Aguila, C.; Zhan, P. J.; Meyer, A. S.; Heiser, L. M.
10.1101/2020.07.24.219907 — cancer biology — Posted on 2021-10-10
2827 Complex fitness landscape shapes variation in a hyperpolymorphic species
Stolyarova, A. V.; Neretina, T. V.; Zvyagina, E. A.; Fedotova, A. V.; Kondrashov, A. S.; Bazykin, G. A.
10.1101/2021.10.10.463656 — evolutionary biology — Posted on 2021-10-10
2830 Inbreeding is associated with shorter early-life telomere length in a wild passerine
Pepke, M. L.; Niskanen, A. K.; Kvalnes, T.; Boner, W.; Saether, B.-E.; Ringsby, T. H.; Jensen, H.
10.1101/2021.10.10.463797 — molecular biology — Posted on 2021-10-10
2831 An ancestral interaction module promotes oligomerisation in divergent mitochondrial ATP synthases
Gahura, O.; Muhleip, A.; Hierro-Yap, C.; Panicucci, B.; Jain, M.; Slapnickov, M.; Amunts, A.; Zikova, A.
10.1101/2021.10.10.463820 — molecular biology — Posted on 2021-10-10
2832 High Resolution Slide-seqV2 Spatial Transcriptomics Enables Discovery of Disease-Specific Cell Neighborhoods and Pathways
Marshall, J. L.; Noel, T.; Wang, Q. S.; Bazua-Valenti, S.; Chen, H.; Murray, E.; Subramanian, A.; Vernon, K. A.; Liguori, K.; Keller, K.; Stickels, R. R.; McBean, B.; Heneghan, R. M.; Weins, A.; Macosko, E. Z.; Chen, F.; Greka, A.
10.1101/2021.10.10.463829 — molecular biology — Posted on 2021-10-10
2836 Early mitochondrial stress and metabolic imbalance lead to photoreceptor cell death in retinal degeneration
Jiang, K.; Mondal, A. K.; Adlakha, Y.; Gumerson, J.; Aponte, A. M.; Gieser, L.; Kim, J.-W.; Boleda, A.; Brooks, M. J.; Nellissery, J.; Fox, D.; Balaban, R. S.; Covian, R.; Swaroop, A.
10.1101/2021.10.10.463827 — neuroscience — Posted on 2021-10-10
2838 Cell-type specific induction of cyclo-oxygenase-2 in layer II/III prefrontal cortical neurons mediates stress-induced anxiety phenotypes in mice.
Fenster, R. J.; McCullough, K.; Naumenko, S.; Thompson, A.; Klengel, C.; Rodgers, A.; Otten, J.; Shu, D.; Harris, N.; Klengel, T.; Ressler, K. J.
10.1101/2021.10.10.463815 — neuroscience — Posted on 2021-10-10
2839 Meeting Measurement Precision Requirements for Effective Engineering of Genetic Regulatory Networks
Beal, J.; Teague, B.; Sexton, J. T.; Castillo-Hair, S.; DeLateur, N. A.; Samineni, M.; Tabor, J. J.; Weiss, R.; Calibrated Flow Cytometry Study Consortium,
10.1101/2021.10.10.460840 — synthetic biology — Posted on 2021-10-10
2842 Membrane phosphoinositides stabilize GPCR-arrestin complexes and offer temporal control of complex assembly and dynamics
Janetzko, J.; Kise, R.; Barsi-Rhyne, B.; Siepe, D. H.; Heydenreich, F. M.; Masureel, M.; Kawakami, K.; Garcia, K. C.; Von Zastrow, M.; Inoue, A.; Kobilka, B. K.
10.1101/2021.10.09.463790 — biochemistry — Posted on 2021-10-10
2845 The genetic history of Mayotte and Madagascar cattle breeds mirrors the complex pattern of human exchanges in Western Indian Ocean
Magnier, J.; Druet, T.; Naves, M.; Ouvrard, M.; Raoul, S.; Janelle, J.; Moazami-Goudarzi, K.; Lesnoff, M.; Tillard, E.; Gautier, M.; Flori, L.
10.1101/2021.10.08.463737 — evolutionary biology — Posted on 2021-10-10
2846 Virulence constrains transmission even in the absence of a genetic trade-off
Godinho, D. P.; Rodrigues, L. R.; Lefevre, S.; Delteil, L.; Mira, A. F.; Fragata, I. R.; Magalhaes, S.; Duncan, A. B.
10.1101/2021.10.07.463510 — evolutionary biology — Posted on 2021-10-10
2850 A nesprin-4/kinesin-1 cargo model for nucleus positioning in cochlear outer hair cells
Taiber, S.; Gozlan, O.; Cohen, R.; Andrade, L.; Moran, Y.; Hipp, R.; Kelley, M. W.; Manor, U.; Sprinzak, D.; Avraham, K. B.
10.1101/2021.10.10.463824 — cell biology — Posted on 2021-10-10
2852 Loss-of-function ROX1 mutations suppress the fluconazole susceptibility of upc2AΔ mutation in Candida glabrata, implicating additional positive regulators of ergosterol biosynthesis
Ollinger, T. L.; Vu, B.; Murante, D.; Parker, J.; Simonicova, L.; Doorley, L. A.; Stamnes, M. A.; Kelly, S. L.; Rogers, P. D.; Moye-Rowley, W. S.; Krysan, D. J.
10.1101/2021.10.07.463606 — microbiology — Posted on 2021-10-10
2853 OpenNeuro: An open resource for sharing of neuroimaging data
Markiewicz, C. J.; Gorgolewski, K. J.; Feingold, F.; Blair, R.; Halchenko, Y. O.; Miller, E.; Hardcastle, N.; Wexler, J.; Esteban, O.; Goncalves, M.; Jwa, A. S.; Poldrack, R.
10.1101/2021.06.28.450168 — neuroscience — Posted on 2021-10-10
2854 Widespread introgression across a phylogeny of 155 Drosophila genomes
Suvorov, A.; Kim, B. Y.; Wang, J.; Armstrong, E. E.; Peede, D.; D'Agostino, E. R. R.; Price, D. K.; Wadell, P.; Lang, M.; Courtier-Orgogozo, V.; David, J. R.; Petrov, D.; Matute, D. R.; Schrider, D. R.; Comeault, A. A.
10.1101/2020.12.14.422758 — evolutionary biology — Posted on 2021-10-10
2856 A consensus-based ensemble approach to improve transcriptome assembly
Voshall, A.; Behera, S.; Li, X.; Yu, X.-H.; Kapil, K.; Deogun, J. S.; Schanklin, J.; Cahoon, E. B.; Moriyama, E. N.
10.1101/2020.06.08.139964 — bioinformatics — Posted on 2021-10-10
2857 Universal prediction of cell cycle position using transfer learning
Zheng, S. C.; Stein-O'Brien, G.; Augustin, J. J.; Slosberg, J.; Carosso, G. A.; Winer, B.; Shin, G.; Bjornsson, H. T.; Goff, L. A.; Hansen, K. D.
10.1101/2021.04.06.438463 — genomics — Posted on 2021-10-10
2861 RAxML Grove: An empirical Phylogenetic Tree Database
Hoehler, D.; Pfeiffer, W.; Ioannidis, V.; Stockinger, H.; Stamatakis, A.
10.1101/2021.10.05.463179 — bioinformatics — Posted on 2021-10-10
2863 Mitochondria serve as axonal shuttle for Cox7c mRNA through mechanism that involves its mitochondrial targeting signal
Cohen, B.; Golani-Armon, A.; Altman, T.; Savulescu, A. F.; Mhlanga, M. M.; Perlson, E.; Arava, Y. S.
10.1101/2021.05.19.444640 — cell biology — Posted on 2021-10-10
2864 Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder
Laghi, V.; Rezelj, V.; Boucontet, L.; Fretaud, M.; Da Costa, B.; Boudinot, P.; Salinas, I.; Lutfalla, G.; Vignuzzi, M.; Levraud, J.-P.
10.1101/2021.04.08.439059 — microbiology — Posted on 2021-10-10
2865 High resolution profiling of MHC-II peptide presentation capacity, by Mammalian Epitope Display, reveals SARS-CoV-2 targets for CD4 T cells and mechanisms of immune-escape
Obermair, F. J.; Renoux, F.; Heer, S.; Lee, C.; Cereghetti, N.; Maestri, G.; Haldner, Y.; Wuigk, R.; Iosefson, O.; Patel, P.; Triebel, K.; Kopf, M.; Swain, J.; Kisielow, J.
10.1101/2021.03.02.433522 — immunology — Posted on 2021-10-10
2866 Not all voxels are created equal: reducing estimation bias in regional NODDI metrics using tissue-weighted means
Parker, C. S.; Veale, T.; Bocchetta, M.; Slattery, C. F.; Malone, I. B.; Thomas, D. L.; Schott, J. M.; Cash, D. M.; Zhang, H.
10.1101/2021.06.29.450089 — neuroscience — Posted on 2021-10-10
2867 PcGCE is a potent elicitor of defense responses in aspen
Donev, E. N.; Derba-Maceluch, M.; Liu, X.; Bwanika, H. C.; Dobrowolska, I.; Thapa, M.; Lesniewska, J.; Simura, J.; Tsai, A. Y.- L.; Boström, D.; Kleczkowski, L. A.; Eriksson, M. E.; Ljung, K.; Master, E. R.; Mellerowicz, E. J.
10.1101/2021.09.23.460629 — bioengineering — Posted on 2021-10-10
2869 Naïve individuals promote collective exploration in homing pigeons
Valentini, G.; Pavlic, T. P.; Walker, S. I.; Pratt, S. C.; Biro, D.; Sasaki, T.
10.1101/2021.04.08.438960 — animal behavior and cognition — Posted on 2021-10-10
2870 Fluorescence exclusion: a rapid, accurate and powerful method for measuring yeast cell volume
Garcia-Ruano, D.; Jain, A.; Ryan, J. C.; Balasubramaniam, V. R.; Venkova, L.; Piel, M.; Coudreuse, D.
10.1101/2021.10.07.463508 — cell biology — Posted on 2021-10-10
2872 COBREXA.jl: constraint-based reconstruction and exascale analysis
Kratochvil, M.; Heirendt, L.; Wilken, S. E.; Pusa, T.; Arreckx, S.; Noronha, A.; van Aalst, M.; Satagopam, V. P.; Ebenhoeh, O.; Schneider, R.; Trefois, C.; Gu, W.
10.1101/2021.06.04.447038 — systems biology — Posted on 2021-10-10
2877 Annotation of Hox cluster and Hox cofactor genes in the Asian citrus psyllid, Diaphorina citri, reveals novel features
Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; DeliaFIXX, T.; Saha, S.
10.1101/2021.10.09.463765 — bioinformatics — Posted on 2021-10-09
2878 Deep learning-based tumor microenvironment segmentation is predictive of tumor mutations and patient survival in non-small-cell lung cancer
Raczkowski, Łukasz; Pasnik, I.; Kukiełka, M.; Nicos, M.; Budzinska, M. A.; Kucharczyk, T.; Szumiło, J.; Krawczyk, P.; Crosetto, N.; Szczurek, E.
10.1101/2021.10.09.462574 — bioinformatics — Posted on 2021-10-09
2880 Annotation of Putative Circadian Rhythm-Associated Genes in Diaphorina citri (Hemiptera : Liviidae)
Reynolds, M.; de Oliveira, L.; Paris, T.; Vosburg, C.; Massimino, C.; Norus, J.; Ortiz, Y.; Espino, M.; Davis, N.; Masse, R.; Neiman, A.; Holcomb, R.; Gervais, K.; Kemp, M.; Hoang, M.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; Delia, T.; Saha, S.
10.1101/2021.10.09.463768 — bioinformatics — Posted on 2021-10-10
2883 Convergent evolution of polyploid genomes from across the eukaryotic tree of life
Hao, Y.; Fleming, J.; Petterson, J.; Lyons, E.; Edger, P. P.; Pires, C.; Thorne, J. L.; Conant, G. C.
10.1101/2021.10.08.463691 — evolutionary biology — Posted on 2021-10-10
2884 Reliability and Stability Challenges in ABCD Task fMRI Data
Kennedy, J. T.; Harms, M. P.; Korucuoglu, O.; Astafiev, S. V.; Barch, D. M.; Thompson, W. K.; Bjork, J. M.; Anokhin, A. P.
10.1101/2021.10.08.463750 — neuroscience — Posted on 2021-10-09
2885 Evaluating Network Threshold Selection for Structural and Functional Brain Connectomes
Theis, N.; Rubin, J.; Cape, J.; Iyengar, S.; Gur, R. E.; Gur, R. C.; Roalf, D. R.; Pogue-Geile, M. F.; Almasy, L.; Nimgaonkar, V. L.; Prasad, K. M.
10.1101/2021.10.09.463759 — neuroscience — Posted on 2021-10-09
2886 SBMate: A Framework for Evaluating Quality of Annotations in Systems Biology Models
Shin, W.; Hellerstein, J. L.; Munarko, Y.; Neal, M. L.; Nickerson, D. P.; Rampadarath, A. K.; Sauro, H. M.; Gennari, J. H.
10.1101/2021.10.09.463757 — systems biology — Posted on 2021-10-09
2894 Trade-off between competition ability and invulnerability to predation in marine microbes; protist grazing versus viral lysis effects
Yang, J. W.; Chang, F.-H.; Yeh, Y.-C.; Tsai, A.-Y.; Chiang, K.-P.; Shiah, F.-K.; Gong, G.-C.; Hsieh, C.-h.
10.1101/2021.10.09.463787 — ecology — Posted on 2021-10-09
2895 Disorder or a new order: how climate change affects phenological variability
Stemkovski, M.; Bell, J. R.; Ellwood, E. R.; Inouye, B. D.; Kobori, H.; Lee, S. D.; Lloyd-Evans, T.; Primack, R. B.; Templ, B.; Pearse, W. D.
10.1101/2021.10.08.463688 — ecology — Posted on 2021-10-09
2897 Repeated administration of 2-hydroxypropyl-β-cyclodextrin (HPβCD) attenuates the chronic inflammatory response to experimental stroke
Becktel, D. A.; Zbesko, J. C.; Frye, J. B.; Chung, A. G.; Hayes, M.; Calderon, K.; Grover, J. W.; Li, A.; Garcia, F. G.; Tavera-Garcia, M. A.; Schnellmann, R. G.; Wu, H.-J. J.; Nguyen, T.-V. V.; Doyle, K. P.
10.1101/2021.05.03.442388 — neuroscience — Posted on 2021-10-09
2900 Mistic: an open-source multiplexed image t-SNE viewer
Prabhakaran, S.; Gatenbee, C.; Robertson-Tessi, M.; West, J.; Beg, A. A.; Gray, J. E.; Antonia, S.; Gatenby, R. A.; Anderson, A. R. A.
10.1101/2021.10.08.463728 — cancer biology — Posted on 2021-10-09
2901 Intermolecular reorganisation of single-componentcondensates during ageing promotes multiphasearchitectures.
Garaizar Suarez, A.; R Espinosa, J.; Joseph, J. A.; Krainer, G.; Shen, Y.; Knowles, T. P. J.; Collepardo-Guevara, R.
10.1101/2021.10.09.463670 — biophysics — Posted on 2021-10-09
2903 Cryptic genetic variations of alanine:glyoxylate aminotransferase shape its fitness and dynamics
Dindo, M.; Pascarelli, S.; Chiasserini, D.; Grottelli, S.; Costantini, C.; Uechi, G.-I.; Giardina, G.; Laurino, P.; Cellini, B.
10.1101/2021.05.24.445519 — biochemistry — Posted on 2021-10-09
2904 Clinical and immunological signatures of severe COVID-19 in previously healthy patients with clonal hematopoiesis
Kang, C. K.; Choi, B.; Kim, S.; Park, S.; Yoon, S. H.; Lee, D.; Lee, A.; Ko, Y.; Chang, E.; Jung, J.; Choe, P. G.; Park, W. B.; Kim, E. S.; Kim, H. B.; Kim, N. J.; Oh, M.-d.; Kim, S.; Im, H.; Kim, J.; Kang, K.; Kang, S.-J.; Lee, Y. H.; Lee, J.; Lee, J. Y.; Moon, J. H.; Song, K.-H.; Koh, Y.; Jung, I.
10.1101/2021.10.05.463271 — immunology — Posted on 2021-10-09
2906 De Novo Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome, an Animal Model for Severe/Critical COVID-19
Andreotti, S.; Altmüller, J.; Quedenau, C.; Borodina, T.; Nouailles, G.; Teixeira Alves, L. G.; Landthaler, M.; Bieniara, M.; Trimpert, J.; Wyler, E.
10.1101/2021.10.02.462569 — genomics — Posted on 2021-10-09
2908 Evolving in the darkness: phylogenomics of Sinocyclocheilus cavefishes highlights recent diversification and cryptic diversity
Mao, T.-R.; Liu, Y.-W.; Vasconcellos, M. M.; Pie, M. R.; Ellepola, G.; Fu, C.-H.; Yang, J.; Meegaskumbura, M.
10.1101/2021.10.09.460971 — evolutionary biology — Posted on 2021-10-09
2909 Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody
Torres, J. L.; Ozorowski, G.; Andreano, E.; Liu, H.; Copps, J.; Piccini, G.; Donnici, L.; Conti, M.; Planchais, C.; Planas, D.; Manganaro, N.; Pantano, E.; Paciello, I.; Pileri, P.; Bruel, T.; Montomoli, E.; Mouquet, H.; Schwartz, O.; Sala, C.; De Francesco, R.; Wilson, I. A.; Rappuoli, R.; Ward, A. B.
10.1101/2021.09.28.462234 — immunology — Posted on 2021-10-09
2911 Broad-scale puma connectivity could restore genomic diversity to fine-scale coastal populations
Gustafson, K. D.; Gagne, R. B.; Buchalski, M. R.; Vickers, T. W.; Riley, S. P.; Sikich, J.; Rudd, J. L.; Dellinger, J. A.; LaCava, M. E.; Ernest, H. B.
10.1101/2021.10.08.463677 — zoology — Posted on 2021-10-09
2914 Islet transplantation tolerance in animals with defined histocompatibility and diabetes
Bhagchandani, P.; Chang, C.; Zhao, W.; Ghila, L.; Herrera, P. L.; Chera, S.; Kim, S. K.
10.1101/2021.10.08.463702 — immunology — Posted on 2021-10-09
2919 Investigating lead removal at trace concentrations from water by inactive yeast cells
Stathatou, P. M.; Athanasiou, C. E.; Tsezos, M.; Goss, J. W.; Blackburn, C.; Tourlomousis, F.; Mershin, A.; Sheldon, B. W.; Padture, N. P.; Darling, E. M.; Gao, H.; Gershenfeld, N.
10.1101/2021.10.07.463380 — bioengineering — Posted on 2021-10-09
2921 A genome-wide epistatic network underlies the molecular architecture of continuous color variation of body extremities: a rabbit model
Demars, J.; Labrune, Y.; Iannuccelli, N.; Deshayes, A.; Leroux, S.; Gilbert, H.; Aymard, P.; Benitez, F.; Riquet, J.
10.1101/2021.10.07.463146 — genetics — Posted on 2021-10-09
2923 Can floral nectars reduce transmission of Leishmania?
Palmer-Young, E.; Schwarz, R.; Chen, Y. P.; Evans, J. D.
10.1101/2021.10.08.463579 — ecology — Posted on 2021-10-09
2924 Early-life immune expression profiles predict later life health and fitness in a wild rodent
Wanelik, K. M.; Begon, M.; Bradley, J. E.; Friberg, I. M.; Taylor, C. H.; Jackson, J. A.; Paterson, S.
10.1101/2021.10.08.463659 — ecology — Posted on 2021-10-09
2925 Trait-environment relationship in tadpoles of the southern Atlantic Forest
dos Santos, R. C.; Brum, D.; Dalmolin, D. A.; Farina, R.; Lucas, E.; Tozetti, A. M.
10.1101/2021.10.08.463663 — ecology — Posted on 2021-10-09
2928 The initiation of the wound healing program is regulated by the convergence of mechanical and epigenetic cues
Bhatt, T.; Hegde, A.; Dey, R.; Ketkar, A.; Pulianmackal, A.; Deb, A.; Rampalli, S.; Jamora, C.
10.1101/2021.10.09.463764 — cell biology — Posted on 2021-10-09
2930 Amikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility
Magallon, J.; Vu, P.; Reeves, C.; Kwan, S.; Phan, K.; Oakley-Havens, C. L.; Rocha, K.; Jimenez, V.; Ramirez, M. S.; Tolmasky, M. E.
10.1101/2021.10.08.463674 — microbiology — Posted on 2021-10-09
2931 Development of a highly sensitive luciferase-based reporter system to study two-step protein secretion in cyanobacteria
Russo, D. A.; Zedler, J. A. Z.; Conradi, F. D.; Schuergers, N.; Jensen, P. E.; Mullineaux, C. W.; Wilde, A.; Pohnert, G.
10.1101/2021.10.08.463751 — microbiology — Posted on 2021-10-09
2932 Longitudinal dynamics of human B-cell response at single-cell level in response to Tdap vaccination
Khatri, I.; Diks, A. M.; van den Akker, E. B.; Oosten, L. E. M.; Zwaginga, J. J.; Reinders, M. J. T.; van Dongen, J. J. M.; Berkowska, M. A.
10.1101/2021.10.08.463649 — immunology — Posted on 2021-10-09
2933 Retrograde adenosine/A2A receptor signaling mediates presynaptic hippocampal LTP and facilitates epileptic seizures
Nasrallah, K.; Berthoux, C.; Hashimotodani, Y.; Chavez, A. E.; Gulfo, M.; Lujan, R.; Castillo, P. E.
10.1101/2021.10.07.463512 — neuroscience — Posted on 2021-10-09
2934 BDNF signaling in Hebbian and Stentian structural plasticity in the developing visual system
Kutsarova, E.; Schohl, A.; Munz, M.; Wang, A.; Zhang, Y. Y.; Bilash, O. M.; Ruthazer, E. S.
10.1101/2021.10.07.463583 — neuroscience — Posted on 2021-10-09
2937 Automated skull stripping in mouse fMRI analysis using 3D U-Net
Ruan, G.; Liu, J.; An, Z.; Wu, K.; Tong, C.; Liu, Q.; Liang, P.; Liang, Z.; Chen, W.; Zhang, X.; Feng, Y.
10.1101/2021.10.08.462356 — neuroscience — Posted on 2021-10-09
2940 An intein-mediated split-nCas9 system for base editing in plants
Yuan, G.; Lu, H.; Hassan, M. M.; Liu, Y.; Li, Y.; Abraham, P. E.; Tuskan, G. A.; Yang, X.
10.1101/2021.10.08.463716 — plant biology — Posted on 2021-10-09
2941 Chloroplast movement and positioning protein CHUP1 is required for focal immunity against Phytophthora infestans
Savage, Z.; Erickson, J. L.; Prautsch, J.; Balmez, A. I.; Tumtas, Y.; Yuen, E. L. H.; Stuttmann, J.; Fantino, E.; Duggan, C.; Molinari, C.; Schattat, M.; Bozkurt, T. O.
10.1101/2021.10.08.463641 — plant biology — Posted on 2021-10-09
2942 Metabolomic and transcriptomic analyses reveal the effects of grafting on anthocyanin synthesis in grapevine
Zhong, H.; Liu, Z.; Zhang, F.; Zhou, X.; Sun, X.; Liu, W.; Xiao, H.; Wang, N.; Pan, M.; Wu, X.; Zhou, Y.
10.1101/2021.10.09.463741 — plant biology — Posted on 2021-10-09
2943 Progressive chromatin silencing of ABA biosynthesis gene permits seed germination in Arabidopsis
Yang, D.; Zhao, F.; Zhu, D.; Chen, X.; Kong, X.; Wu, Y.; Chen, M.; Du, J.; Qu, L.-J.; Wu, Z.
10.1101/2021.10.08.463712 — plant biology — Posted on 2021-10-09
2947 A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression
Culbertson, B.; Garcia, K.; Markett, D.; Asgharian, H.; Chen, L.; Fish, L.; Navickas, A.; Yu, J.; Woo, B.; Nanda, S.; Rabinowitz, J.; Goodarzi, H.
10.1101/2021.10.08.463652 — cancer biology — Posted on 2021-10-09
2952 Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs
Ringel, A. R.; Szabo, Q.; Chiariello, A. M.; Chudzik, K.; Schoepflin, R.; Rothe, P.; Mattei, A. L.; Zehnder, T.; Harnett, D.; Laupert, V.; Bianco, S.; Hetzel, S.; Phan, M.; Schindler, M.; Ibrahim, D.; Paliou, C.; Esposito, A.; Prada-Medina, C. A.; Haas, S.; Giere, P.; Vingron, M.; Wittler, L.; Meissner, A.; Nicodemi, M.; Cavalli, G.; Bantignies, F.; Mundlos, S.; Robson, M. I.
10.1101/2021.10.08.463672 — genetics — Posted on 2021-10-09
2956 Polygenic sex determination produces modular sex polymorphism in an African cichlid fish
Moore, E. C.; Ciccotto, P. J.; Peterson, E. N.; Lamm, M. S.; Albertson, R. C.; Roberts, R. B.
10.1101/2021.10.09.463756 — evolutionary biology — Posted on 2021-10-09
2959 Global port survey quantifies commercial shippings effect on biodiversity
Andres, J. A.; Czechowski, P.; Grey, E.; Saebi, M.; Andres, K.; Brown, C.; Chawla, N.; Corbett, J. J.; Brys, R.; Cassey, P.; Correa, N.; Deveney, M. R.; Egan, S. P.; Fisher, J. P.; vanden Hooff, R.; Knapp, C. R.; Leong, S. C. Y.; Neilson, B. J.; Paolucci, E. M.; Pfrender, M. E.; Pochard, M. R.; Prowse, T. A.; Rumrill, S. S.; Scianni, C.; Sylvester, F.; Tamburri, M. N.; Therriault, T. W.; Yeo, D. C.; Lodge, D.
10.1101/2021.10.07.463538 — ecology — Posted on 2021-10-09
2961 Social information use for spatial decision in Zootoca vivipara
Brevet, M.; Jacob, S.; Rutschmann, A.; Richard, M.; Cote, J.; Clobert, J.
10.1101/2021.10.08.463627 — ecology — Posted on 2021-10-09
2964 Development and retinal remodeling in the brown anole lizard (Anolis sagrei)
Rasys, A. M.; Pau, S. H.; Irwin, K. E.; Luo, S.; Kim, H. Q.; Wahle, M. A.; Menke, D. B.; Lauderdale, J. D.
10.1101/2021.10.07.462409 — developmental biology — Posted on 2021-10-09
2965 Endoglin deficiency elicits hypoxia-driven congestive heart failure in zebrafish.
Lelievre, E.; Bureau, C.; Bordat, Y.; Fretaud, M.; Langevin, C.; Jopling, C.; Kissa, K.
10.1101/2021.10.09.463775 — developmental biology — Posted on 2021-10-09
2966 Self-organized tissue mechanics underlie embryonic regulation
Caldarelli, P.; Chamolly, A.; Alegria-Prevot, O.; Gros, J.; Corson, F.
10.1101/2021.10.08.463661 — developmental biology — Posted on 2021-10-09
2967 The prion and HSP104 modulate cytochrome c oxidase deficiency caused by deletion of COX12
Saini, P. K.; Dawitz, H.; Aufschnaiter, A.; Thomas, J.; Amblard, A.; Stewart, J.; Thierry-Mieg, N.; Ott, M.; Pierrel, F.
10.1101/2021.10.08.463630 — cell biology — Posted on 2021-10-09
2968 Kidney pathological changes alter cell clustering features in single-cell RNA sequencing
Ma, L.; Murea, M.; Choi, Y. A.; Hemal, A. K.; Mikhailov, A. V.; Snipes, J. A.; Chou, J. W.; Cui, W.; Miller, L. D.; Hawkins, G. A.; Palmer, N. D.; Langefeld, C. D.; Freedman, B. I.
10.1101/2021.10.08.463030 — cell biology — Posted on 2021-10-09
2969 Proximity interactome of LC3B in normal growth conditions
Nollet, M.; Agrotis, A.; Michailidis, F.; Dokal, A. D.; Rajeeve, V.; Burden, J.; Nightingale, T. D.; Cutillas, P.; Ketteler, R.; Kermorgant, S.
10.1101/2021.10.08.463639 — cell biology — Posted on 2021-10-09
2970 In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris
Rybak, J. M.; Barker, K. S.; Munoz, J. F.; Parker, J. E.; Ahmad, S.; Mokaddas, E.; Abdullah, A.; Elhagracy, R. S.; Kelly, S. L.; Cuomo, C. A.; Rogers, P. D.
10.1101/2021.10.08.463721 — microbiology — Posted on 2021-10-09
2972 Persistent Immunogenicity of Integrase Defective Lentiviral Vectors delivering membrane tethered Native-Like HIV-1 Envelope Trimers
Gallinaro, A.; Pirillo, M. F.; Aldon, Y.; Cecchetti, S.; Michelini, Z.; Tinari, A.; Borghi, M.; Canitano, A.; McKay, P. F.; Bona, R.; Vescio, M. F.; Grasso, F.; Blasi, M.; Baroncelli, S.; Scarlatti, G.; LaBranche, C.; Montefiori, D.; Klotman, M. E.; Sanders, R. W.; Shattock, R.; Negri, D.; Cara, A.
10.1101/2021.10.08.462761 — immunology — Posted on 2021-10-09
2973 Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus
Takeshima, Y.; Iwasaki, Y.; Nakano, M.; Narushima, Y.; Ota, M.; Nagafuchi, Y.; Sumitomo, S.; Okamura, T.; Elkon, K. B.; Ishigaki, K.; Suzuki, A.; Kochi, Y.; Yamamoto, K.; Fujio, K.
10.1101/2021.10.08.463629 — immunology — Posted on 2021-10-09
2975 Impact of stimulation location relative to grey and white matter on single pulse electrical stimulation responses in the human brain
Paulk, A. C.; Zelmann, R.; Crocker, B.; Widge, A. S.; Dougherty, D. D.; Eskandar, E. N.; Weisholtz, D. S.; Richardson, M.; Cosgrove, R.; Cash, S. S.
10.1101/2021.10.07.463524 — neuroscience — Posted on 2021-10-09
2977 Multimodal Magnetic Resonance Histology and Light Sheet Imaging for Quantitative Neurogenetics of the Mouse
Johnson, G. A.; Cofer, G.; Cook, J.; Gee, J.; Hall, A.; Hornburg, K. J.; Qi, Y.; Tian, Y.; Yeh, F.-c.; Wang, N.; White, L.; Williams, R. W.
10.1101/2021.10.08.463660 — neuroscience — Posted on 2021-10-09
2978 CCR5 closes the temporal window for memory linking
Shen, Y.; Zhou, M.; Cai, D.; Almeida Filho, D.; Fernandes, G.; Cai, Y.; Kim, N.; Necula, D.; Zhou, C.; Liu, A.; Kang, X.; Kamata, M.; Lavi, A.; Huang, S.; Silva, T.; Heo, W. D.; Silva, A. J.
10.1101/2021.10.07.463602 — neuroscience — Posted on 2021-10-09
2980 Light-induced asymmetries in the embryonic retina are mediated by the vascular system and extracellular matrix
Versace, E.; Sgado, P.; George, J.; Loveland, J.; Ward, J.; Thorpe, P.; Jensen, L. J.; Spencer, K.; Paracchini, S.; Vallortigara, G.
10.1101/2021.10.08.463575 — neuroscience — Posted on 2021-10-09
2982 Sunk cost sensitivity in mice, rats, and humans on the Restaurant Row and WebSurf tasks cannot be explained by attrition biases alone
Redish, A. D.; Sweis, B. M.; Abram, S.; Duin, A.; Kazinka, R.; Kocharian, A.; MacDonald, A.; Schmidt, B.; Schmitzer-Torbert, N.; Thomas, M.
10.1101/2021.10.07.462802 — neuroscience — Posted on 2021-10-09
2985 Age-related change in task-evoked amygdala-prefrontal circuitry: a multiverse approach with an accelerated longitudinal cohort aged 4-22 years
Bloom, P. A.; VanTieghem, M.; Gabard-Durnam, L.; Gee, D. G.; Flannery, J.; Caldera, C.; Goff, B.; Telzer, E. H.; Humphreys, K. L.; Fareri, D. S.; Shapiro, M.; Algharazi, S.; Bolger, N.; Aly, M.; Tottenham, N.
10.1101/2021.10.08.463601 — neuroscience — Posted on 2021-10-09
2987 Metformin-mediated mitochondrial protection post-cardiac arrest improves EEG activity and confers neuroprotection and survival benefit
Shoaib, M.; Choudhary, R. C.; Chillale, R. K.; Kim, N.; Miyara, S. J.; Haque, S.; Yin, T.; Frankfurt, M.; Molmenti, E. P.; Zanos, S.; Kim, J.; Becker, L. B.
10.1101/2021.10.07.460078 — neuroscience — Posted on 2021-10-09
2989 Disrupted intrinsic connectivity links to language and social deficits in toddlers with autism
Xiao, Y.; Wen, T. H.; Kupis, L.; Eyler, L. T.; Goel, D.; Lombardo, M. V.; Pierce, K.; Courchesne, E.
10.1101/2021.10.08.463640 — neuroscience — Posted on 2021-10-09
3001 EXTRA LARGE G-PROTEIN 2 (XLG2) mediates cell death and hyperimmunity via a novel, apoplastic ROS-independent pathway in Arabidopsis thaliana
Petutschnig, E. K.; Anders, J.; Stolze, M.; Meusel, C.; Hacke, R.; Schwier, M. A.; Gippert, A.-L.; Kroll, S.; Fasshauer, P.; Wiermer, M.; Lipka, V.
10.1101/2021.10.08.463358 — plant biology — Posted on 2021-10-09
3005 In silico discovery of small molecules for efficient stem cell differentiation into definitive endoderm
Novakovsky, G.; Sasaki, S.; Fornes, O.; Omur, M. E.; Huang, H.; Lim, N.; Pavlidis, P.; Cherkasov, A.; Mostafavi, S.; Lynn, F. C.; Wasserman, W. W.
10.1101/2021.10.06.463418 — bioinformatics — Posted on 2021-10-09
3011 Shiitake mycelium fermentation improves digestibility, nutritional value, flavor and functionality of plant proteins
Nadal, M.; Clark, A. J.; Soni, B.; Sharkey, B.; Acree, T.; Lavin, E.; Bailey, H.; Stein, H.; Han, A.; Elie, M.
10.1101/2021.10.07.463529 — bioengineering — Posted on 2021-10-09
3012 An Anatomically and Hemodynamically Realistic Simulation Framework for 3D Ultrasound Localization Microscopy
Belgharbi, H.; Poree, J.; Damseh, R.; Perrot, V.; Delafontaine-Martel, P.; Lesage, F.; Provost, J.; Milecki, L.
10.1101/2021.10.08.463259 — bioengineering — Posted on 2021-10-09
3019 Prioritizing Management for Cumulative Impacts
Singh, G.; Rhodes, J.; McDonald-Madden, E.; Possingham, H.; Hammill, E.; Clarke Murray, C.; Mach, M.; Martone, R.; Halpern, B.; Satterfield, T.; Chan, K.
10.1101/2021.10.07.463502 — ecology — Posted on 2021-10-09
3020 Genetic patterns in Montipora capitata across an environmental mosaic in Kaneohe Bay
Caruso, C.; Rocha de Souza, M.; Ruiz-Jones, L.; Conetta, D.; Hancock, J.; Hobbs, C.; Hobbs, C.; Kahkejian, V.; Kitchen, R.; Marin, C.; Monismith, S.; Madin, J.; Gates, R. D.; Drury, C.
10.1101/2021.10.07.463582 — ecology — Posted on 2021-10-09
3021 Low heritability and high phenotypic plasticity of salivary cortisol in response to environmental heterogeneity in fur seals
Nagel, R.; Kaiser, S.; Stainfield, C.; Toscani, C.; Fox-Clarke, C.; Paijmans, A. J.; Costa Castro, C.; Vendrami, D. J.; Forcada, J.; Hoffman, J. I.
10.1101/2021.10.08.463664 — ecology — Posted on 2021-10-09
3024 Precise control of microtubule disassembly in living cells
Liu, G. Y.; Chen, S.-C.; Shaiv, K.; Hong, S.-R.; Yang, W.-T.; Huang, S.-H.; Chang, Y.-C.; LIN, Y.-C.
10.1101/2021.10.08.463668 — cell biology — Posted on 2021-10-09
3025 A Proposed Unified Interphase Nucleus Chromosome Structure: Preliminary Preponderance of Evidence
Sedat, J.; McDonald, A.; Cang, H.; Lucas, J. S.; Arigovindan, M.; Kam, Z.; Murre, C.; Elbaum, M.
10.1101/2021.10.08.463051 — cell biology — Posted on 2021-10-09
3026 Peroxisome-derived hydrogen peroxide can modulate the sulfenylation profiles of key redox signaling proteins
Lismont, C.; Revenco, I.; Li, H.; Costa, C.; Lenaerts, L.; Hussein, M.; De Bie, J.; Knoops, B.; Van Veldhoven, P. P.; Derua, R.; Fransen, M.
10.1101/2021.10.08.463647 — cell biology — Posted on 2021-10-09
3027 Nanchangmycin regulates FYN, FAK and ERK to control the fibrotic activity of hepatic stellate cells
Li, W.; Chen, J. Y.; Sun, C.; Sparks, R. P.; Pantano, L.; Rahman, R.-U.; Moran, S. P.; Pondick, J. V.; Kirchner, R.; Wrobel, D.; Bieler, M.; Ho Sui, S. J.; Doerner, J. F.; Rippmann, J. F.; Mullen, A. C.
10.1101/2021.10.08.463221 — cell biology — Posted on 2021-10-09
3028 Targeting a central feature of asthma using a cell type-selective IL-13-responsive enhancer
Koh, K. D.; Bonser, L. R.; Eckalbar, W. L.; Shen, J.; Yizhar-Barnea, O.; Zeng, X.; Sun, D. I.; Zlock, L. T.; Finkbeiner, W. E.; Ahituv, N.; Erle, D. J.
10.1101/2021.10.08.463596 — immunology — Posted on 2021-10-09
3030 Patient-Derived Organoids Recapitulate Intrinsic Immune Landscapes and Progenitor Populations of Glioblastoma.
Watanabe, F.; Hollingsworth, E. W.; Bartley, J. M.; Wisehart, L.; Desai, R.; Hartlaub, A. M.; Hester, M. E.; Schiapparelli, P.; Hinojosa, A. Q.; Imitola, J.
10.1101/2021.10.06.463228 — neuroscience — Posted on 2021-10-09
3032 Self-regulation of the brain's Beta rhythm using a brain-computer interface improves inhibitory control
Enz, N.; Schmidt, J.; Nolan, K.; Mitchell, M.; Alvarez Gomez, S.; Alkayyali, M.; Cambay, P.; Gippert, M.; Whelan, R.; Ruddy, K. L.
10.1101/2021.10.07.463487 — neuroscience — Posted on 2021-10-09
3033 The Role of the Temporal Pole in Temporal Lobe Epilepsy: A Diffusion Kurtosis Imaging Study
Kasa, L. W.; Peters, T.; Mirsattari, S. M.; Jurkiewicz, M. T.; Khan, A. R.; Haast, R. A.
10.1101/2021.10.07.463554 — neuroscience — Posted on 2021-10-09
3034 Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder
Xue, X.; Zong, W.; Glausier, J.; Kim, S.-M.; Shelton, M.; Phan, B. N.; Srinivasan, C.; Pfenning, A. R.; Tseng, G.; Lewis, D. A.; Seney, M.; Logan, R.
10.1101/2021.10.07.463568 — neuroscience — Posted on 2021-10-09
3035 The value of corticospinal excitability and intracortical inhibition in predicting motor skill improvement driven by action observation
Nuara, A.; Bazzini, M. C.; Cardellicchio, P.; Scalona, E.; De Marco, D.; Rizzolatti, G.; Fabbri-Destro, M.; Avanzini, P.
10.1101/2021.10.07.463481 — neuroscience — Posted on 2021-10-09
3036 Preserved motor representations after paralysis
Guan, C.; Aflalo, T.; Zhang, C.; Rosario, E. R.; Pouratian, N.; Andersen, R. A.
10.1101/2021.10.07.463105 — neuroscience — Posted on 2021-10-09
3037 Covert valuation for information sampling and choice
Butler, J. L.; Muller, T. H.; Veselic, S.; Malalasekera, W. M. N.; Hunt, L. T.; Behrens, T. E. J.; Kennerley, S. W.
10.1101/2021.10.08.463476 — neuroscience — Posted on 2021-10-09
3039 Global Plant Extinction Risk Assessment Informs Novel Biodiversity Hotspots
Haevermans, T.; Tressou, J.; Kwon, J.; Pellens, R.; Dubearnes, A.; Veron, S.; Bel, L.; Dervaux, S.; Dibie-Barthelemy, J.; Gaudeul, M.; Govaerts, R.; Le Bras, G.; Muller, S.; Rouhan, G.; Sarthou, C.; Soler, L.
10.1101/2021.10.08.463027 — plant biology — Posted on 2021-10-09
3044 Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis
Johari, M.; Vihola, A.; Palmio, J.; Jokela, M.; Jonson, P. H.; Sarparanta, J.; Huovinen, S.; Savarese, M.; Hackman, P.; Udd, B.
10.1101/2021.06.30.450477 — neuroscience — Posted on 2021-10-09
3046 Predicting compound activity from phenotypic profiles and chemical structures
Caicedo, J. C.; Moshkov, N.; Becker, T.; Yang, K.; Horvath, P.; Dancik, V. C.; Wagner, B. K.; Clemons, P. C.; Singh, S.; Carpenter, A. E.
10.1101/2020.12.15.422887 — bioinformatics — Posted on 2021-10-09
3048 Balancing selection of the Intracellular Pathogen Response in natural Caenorhabditis elegans populations
van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Wilten, J. I. H. A.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G.
10.1101/579151 — genetics — Posted on 2021-10-09
3050 Gut Bacterial Dysbiosis and Instability is Associated with the Onset of Complications and Mortality in COVID-19
Schult, D.; Reitmeier, S.; Koyumdzhieva, P.; Middelhof, M.; Erber, J.; Schneider, J.; Krager, J.; Frolova, M.; Horstmann, J.; Fricke, L.; Steiger, K.; Jesinghaus, M.; Janssen, K.-P.; Protzer, U.; Neuhaus, K.; Schmid, R. M.; Haller, D.; Quante, M.
10.1101/2021.10.08.463613 — microbiology — Posted on 2021-10-09
3051 SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
Qiao, W.; Lau, H. E.; Xie, H.; Poon, V. K. M.; Chan, C. C. S.; Chu, H.; Yuan, S.; Yuen, T. T. T.; Chik, K. K. H.; Tsang, J. O. L.; Chan, C. C. Y.; Cai, J.-P.; Luo, C.; Yuen, K.-Y.; Cheung, K. M. C.; Chan, J. F. W.; Yeung, K. W. K.
10.1101/2021.10.08.463665 — microbiology — Posted on 2021-10-09
3052 Comprehensive antibody profiling of mRNA vaccination in children
Bartsch, Y. C.; St Denis, K. J.; Kaplonek, P.; Kang, J.; Lam, E. C.; Farkas, E. J.; Davis, J.; Boribong, B.; Shreffler, W.; Balazs, A. B.; Yonker, L. M.; Galit, A.
10.1101/2021.10.07.463592 — immunology — Posted on 2021-10-09
3053 Astrocytic extracellular vesicles modulate neuronal calcium homeostasis via transglutaminase-2
Tonoli, E.; Verduci, I.; Prada, I.; Forcaia, G.; Gabrielli, M.; Coveney, C.; Savoca, M. P.; Boocock, D. J.; Sancini, G.; Mazzanti, M.; Verderio, C.; Verderio, E. A. M.
10.1101/2021.09.30.462507 — neuroscience — Posted on 2021-10-09
3056 Development and Validation of a MALDI-TOF-Based Model to Predict Extended-Spectrum Beta-Lactamase and/or Carbapenemase-Producing in Klebsiella pneumoniae Clinical Isolates
Guerrero-Lopez, A.; Candela, A.; Sevilla-Salcedo, C.; Hernandez-Garcia, M.; Olmos, P. M.; Cercenado, E.; Canton, R.; Muñoz, P.; del Campo, R.; Gomez-Verdejo, V.; Rodriguez-Sanchez, B.
10.1101/2021.10.04.463058 — microbiology — Posted on 2021-10-09
3057 Assembling Long Accurate Reads Using Multiplex de Bruijn Graphs
Bankevich, A.; Bzikadze, A. V.; Kolmogorov, M.; Antipov, D.; Pevzner, P.
10.1101/2020.12.10.420448 — bioinformatics — Posted on 2021-10-09
3058 Fully resolved assembly of Cryptosporidium parvum
Menon, V. K.; Okhuysen, P. C.; Chappell, C.; Mahmoud, M.; Mahmoud, M.; Meng, Q.; Vee, V.; Doddapaneni, H.; Han, Y.; Salvi, S.; Bhamidipati, S.; Kottapalli, K.; Weissenberger, G.; Shen, H.; Ross, M. C.; Hoffman, K. L.; Cregeen, S. J.; Muzny, D. M.; Metcalf, G. A.; Gibbs, R. A.; Petrosino, J. F.; Sedlazeck, F. J.
10.1101/2021.07.07.451495 — genomics — Posted on 2021-10-09
3061 Osteoblast-osteoclast co-cultures: a systematic review and map of available literature
Remmers, S. J. A.; de Wildt, B. W. M.; Vis, M. A. M.; Spaander, E. S. R.; de Vries, R. B. M.; Ito, K.; Hofmann, S.
10.1101/2021.09.09.459671 — cell biology — Posted on 2021-10-09
3064 Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease
Iovino, L.; Giusti, V.; Pischedda, F.; Giusto, E.; Plotegher, N.; Marte, A.; Battisti, I.; Di Iacovo, A.; Marku, A.; Piccoli, G.; Bandopadhyay, R.; Perego, C.; Bonifacino, T.; Bonanno, G.; Roseti, C.; Bossi, E.; Arrigoni, G.; Bubacco, L.; Greggio, E.; Hilfiker, S.; Civiero, L.
10.1101/2021.08.04.455053 — neuroscience — Posted on 2021-10-09
3067 A Hybrid High-Resolution Anatomical MRI Atlas with Sub-parcellation of Cortical Gyri using Resting fMRI
Joshi, A. A.; Choi, S.; Liu, Y.; Chong, M.; Sonkar, G.; Gonzalez-Martinez, J.; Nair, D.; Wisnowski, J.; Haldar, J.; Shattuck, D.; Damasio, H.; Leahy, R. M.
10.1101/2020.09.12.294322 — bioinformatics — Posted on 2021-10-09
3068 A sensitive and specific genetically encodable biosensor for potassium ions
Wu, S.-Y.; Wen, Y.; Serre, N. B. C.; Laursen, C. C. H.; Dietz, A. G.; Taylor, B. R.; Aggarwal, A.; Rancic, V.; Becker, M.; Ballanyi, K.; Podgorski, K.; Hirase, H.; Nedergaard, M.; Fendrych, M.; Lemieux, M. J.; Eberl, D. F.; Kay, A. R.; Campbell, R. E.; Shen, Y.
10.1101/2021.10.07.463410 — bioengineering — Posted on 2021-10-09
3070 Insights into Mus musculus subspecies population structure across Eurasia revealed by whole-genome sequence analysis
Fujiwara, K.; Kawai, Y.; Moriwaki, K.; Takada, T.; Shiroishi, T.; Saitou, N.; Suzuki, H.; Osada, N.
10.1101/2021.02.05.429881 — genomics — Posted on 2021-10-09
3071 No evidence for a special role of language in feature-based categorization
Benn, Y.; Ivanova, A. A.; Clark, O.; Mineroff, Z.; Seikus, C.; Santos Silva, J.; Varley, R.; Fedorenko, E.
10.1101/2021.03.18.436075 — neuroscience — Posted on 2021-10-08
3072 CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication
Harper, K. L.; Mottram, T. J.; Arene, C. A.; Foster, B.; Patterson, M. R.; McDonnell, E.; Macdonald, A.; Westhead, D.; Whitehouse, A.
10.1101/2021.10.07.463491 — microbiology — Posted on 2021-10-08
3074 Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity
Rizo, J.; Roggero, C. M.; Esser, V.; Duan, L.; Rice, A. M.; Ma, S.; Raj, G. V.; Rosen, M. K.; Liu, Z.-P.
10.1101/2021.10.08.463684 — cancer biology — Posted on 2021-10-08
3076 Sub-second multi-channel magnetic control of select neural circuits in behaving flies
Sebesta, C.; Torres Hinojosa, D.; Wang, B.; Asfouri, J.; Li, Z.; Duret, G.; Jiang, K.; Xiao, Z.; Zhang, L.; Zhang, Q.; Colvin, V.; Goetz, S. M.; Peterchev, A. V.; Dierick, H.; Bao, G.; Robinson, J. T.
10.1101/2021.03.15.435264 — bioengineering — Posted on 2021-10-08
3077 Selective whole genome amplification as a tool to enrich specimens with low Treponema pallidum genomic DNA copies for whole genome sequencing
Thurlow, C. M.; Joseph, S. J.; Ganova-Raeva, L. M.; Katz, S.; Pereira, L.; Chen, C.-Y.; Debra, A.; Vilfort, K.; Workowski, K.; Cohen, S.; Reno, H.; Sun, Y.; Burroughs, M.; Sheth, M.; Chi, K.-H.; Danavall, D.; Philip, S.; Cao, W.; Kersh, E.; Pillay, A.
10.1101/2021.07.09.451864 — genomics — Posted on 2021-10-08
3078 Transgenic Drosophila lines for LexA-dependent gene and growth regulation
Chang, K. R.; Tsao, D. D.; Bennett, C.; Wang, E.; Floyd, J. F.; Greenwald, E.; Kim, E. S.; Griffin, C.; Morse, E.; Chisholm, T.; Rankin, A. E.; Lopez, L. A. B.; Lantz, N.; Fox, E.; Kockel, L.; Kim, S. K.; Park, S.
10.1101/2021.10.07.463520 — genetics — Posted on 2021-10-08
3081 Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM
Pathania, M.; Tosi, T.; Millership, C.; Hoshiga, F.; Morgan, R. M. L.; Freemont, P. S.; Grundling, A.
10.1101/2021.05.26.445777 — microbiology — Posted on 2021-10-08
3082 A conserved uORF regulates APOBEC3G translation and is targeted by HIV-1 Vif protein to repress the antiviral factor
Libre, C.; Seissler, T.; Guerrero, S.; Batisse, J.; Verriez, C.; Stupfler, B.; Gilmer, O.; Cabrera-Rodriguez, R.; Weber, M. M.; Valenzuela-Fernandez, A.; Cimarelli, A.; Etienne, L.; Marquet, R.; Paillart, J.-C.
10.1101/2021.01.13.426487 — microbiology — Posted on 2021-10-08
3085 VIP interneurons in mouse whisker S1 exhibit sensory and action-related signals during goal-directed behavior
Ramamurthy, D. L.; Chen, A.; Huang, P. C.; Bharghavan, P.; Krishna, G.; Casale, K.; Feldman, D. E.
10.1101/2021.10.08.463283 — neuroscience — Posted on 2021-10-08
3088 Non-invasive imaging of gene expression and protein secretion dynamics in living mice: identification of ectopic prothrombin expression as driver of thrombosis in cancer
Nourse, J.; Tokalov, S.; Khokhar, S.; Khan, E.; Schott, L. K.; Hinz, L.; Eder, L.; Arnold-Schild, D.; Lackner, K. J.; Ten Cate, H.; Probst, H. C.; Danckwardt, S.
10.1101/2021.07.08.451623 — genetics — Posted on 2021-10-08
3089 Coevolution of interacting proteins through non-contacting and non-specific mutations
Ding, D.; Green, A. G.; Wang, B.; Lite, T.-L. V.; Weinstein, E. N.; Marks, D. S.; Laub, M. T.
10.1101/2021.10.07.463098 — evolutionary biology — Posted on 2021-10-08
3092 Host genetic control of succession in the switchgrass leaf fungal microbiome
VanWallendael, A.; Benucci, G. M. N.; da Costa, P. B.; Fraser, L.; Bonito, G.; Fritschi, F. B.; Juenger, T. E.; Lovell, J. T.; Sreedasyam, A.; Lowry, D.
10.1101/2021.03.26.437207 — ecology — Posted on 2021-10-08
3095 Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design
Adolf-Bryfogle, J.; Labonte, J. W.; Kraft, J. C.; Shapovalov, M.; Raemisch, S.; Lutteke, T.; Dimaio, F.; Bahl, C. D.; Pallesen, J.; King, N. P.; Gray, J. J.; Kulp, D. W.; Schief, W. R.
10.1101/2021.09.27.462000 — molecular biology — Posted on 2021-10-08
3097 High-throughput mutagenesis identifies mutations and RNA binding proteins controlling CD19 splicing and CART-19 therapy resistance
Cortes-Lopez, M.; Schulz, L.; Enculescu, M.; Paret, C.; Spiekermann, B.; Busch, A.; Orekhova, A.; Kielisch, F.; Quesnel-Vallieres, M.; Torres-Diz, M.; Faber, J.; Barash, Y.; Thomas-Tikhonenko, A.; Zarnack, K.; Legewie, S.; König, J.
10.1101/2021.10.08.463671 — molecular biology — Posted on 2021-10-08
3099 Genome-wide identification of tomato xylem sap fitness factors for three plant-pathogenic Ralstonia species
Georgoulis, S. J.; Shalvarjian, K. E.; Helmann, T. C.; Hamilton, C. D.; Carlson, H. K.; Deutschbauer, A. M.; Lowe-Power, T. M.
10.1101/2020.08.31.276741 — microbiology — Posted on 2021-10-08
3100 Single-cell RNA transcriptome analysis reveals CXCL16/CXCR6 as maintenance factors for CNS tissue resident T cells that drive synapse elimination during viral recovery
Rosen, S.; Soung, A. L.; Yang, W.; Ai, S.; Kanmogne, M.; Dave, V. A.; Prabhakar, S.; Swain, A.; Artyomov, M.; Magee, J. A.; Klein, R. S.
10.1101/2021.10.08.463715 — immunology — Posted on 2021-10-08
3101 A TIR-1/SARM1 phase transition underlies p38 immune pathway activation in the C. elegans intestine
Peterson, N. D.; Icso, J. D.; Salisbury, J. E.; Rodriguez, T. C.; Thompson, P.; Pukkila-Worley, R.
10.1101/2021.08.05.455128 — immunology — Posted on 2021-10-08
3102 The Neural Basis of Delayed Gratification
Gao, Z.; Wang, H.; Lu, C.; Lu, T.; Froudist-Walsh, S.; Chen, M.; Wang, X.-J.; Hu, J.; Sun, W.
10.1101/2021.03.10.434739 — neuroscience — Posted on 2021-10-08
3104 Post-stroke administration of the p75 neurotrophin receptor modulator, LM11A-31, attenuates chronic changes in brain metabolism, increases neurotransmitter levels, and improves recovery
Nguyen, T.-V. V.; Crumpacker, R. H.; Calderon, K. E.; Garcia, F. G.; Zbesko, J. C.; Frye, J. B.; Gonzalez, S.; Becktel, D. A.; Yang, T.; Tavera-Garcia, M. A.; Morrison, H. W.; Schnellmann, R. G.; Longo, F. M.; Doyle, K. P.
10.1101/2021.04.30.442181 — neuroscience — Posted on 2021-10-08
3107 Platinum chemotherapy induces lymphangiogenesis in cancerous and healthy tissues that can be prevented with adjuvant anti-VEGFR3 therapy
Harris, A. R.; Esparza, S.; Azimi, M. S.; Cornelison, R.; Azar, F. N.; Llaneza, D. C.; Belanger, M.; Mathew, A.; Tkachenko, S.; Perez, M. J.; Buchta Rosean, C.; Bostic, R.; Cornelison, R. C.; Tate, K. M.; Peirce-Cottler, S. M.; Paquette, C.; Mills, A.; Landen, C. N.; Saucerman, J.; Dillon, P. M.; Pompano, R. R.; Rutkowski, M. A.; Munson, J.
10.1101/781443 — cancer biology — Posted on 2021-10-08
3108 A mechanobiological model for tumor spheroids evolution: application to glioblastoma
Carrasco-Mantis, A.; Castro-Abril, H.; Randelovic, T.; Ochoa, I.; Doblare, M.; Sanz-Herrera, J. A.
10.1101/2021.10.08.463617 — biophysics — Posted on 2021-10-08
3111 Pseudofinder: detection of pseudogenes in prokaryotic genomes
Syberg-Olsen, M. J.; Garber, A. I.; Keeling, P. J.; McCutcheon, J.; Husnik, F.
10.1101/2021.10.07.463580 — bioinformatics — Posted on 2021-10-08
3112 Deep Learning-Inferred Multiplex ImmunoFluorescence for IHC Image Quantification
Ghahremani, P.; Li, Y.; Kaufman, A.; Vanguri, R.; Greenwald, N.; Angelo, M.; Hollmann, T. J.; Nadeem, S.
10.1101/2021.05.01.442219 — bioinformatics — Posted on 2021-10-08
3114 Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites
Dietzen, N. M.; Arcario, M. J.; Chen, L. J.; Petroff, J. T.; Krishnan, K.; Brannigan, G.; Covey, D. F.; Cheng, W. W.
10.1101/2021.10.08.463634 — biochemistry — Posted on 2021-10-08
3115 Prolactin and prolactin receptor expression in the HPG axis and crop sac during parental care in both sexes of a biparental bird (Columba livia)
Farrar, V. S.; Harris, R. M.; Austin, S. H.; Nava Ultreras, B. M.; Booth, A. M.; Angelier, F.; Lang, A.; Feustel, T.; Lee, C.; Bond, A.; MacManes, M. D.; Calisi, R. M.
10.1101/2021.07.13.452208 — animal behavior and cognition — Posted on 2021-10-08
3117 Can DNA help trace the local trade of pangolins? A genetic assessment of white-bellied pangolins from the Dahomey Gap (West Africa)
Zanvo, S.; Djagoun, S. C. A. M.; Azihou, A. F.; Djossa, B.; Afiademanyo, K.; Olayemi, A.; Agbangla, C.; Sinsin, B.; Gaubert, P.
10.1101/2021.10.07.463484 — genetics — Posted on 2021-10-08
3119 3D imaging for the quantification of spatial patterns in microbiota of the intestinal mucosa
Mondragon-Palomino, O.; Poceviciute, R.; Lignell, A.; Griffiths, J. A.; Takko, H.; Ismagilov, R. F.
10.1101/2021.10.07.463215 — microbiology — Posted on 2021-10-08
3125 CRISPR-Cas9-mediated knockout of CYP79D1 and CYP79D2 in cassava attenuates toxic cyanogen production
Gomez, M. A.; Berkoff, K. C.; Gill, B. K.; Iavarone, A. T.; Lieberman, S. E.; Ma, J. M.; Schultink, A.; Wyman, S. K.; Chauhan, R. D.; Taylor, N. J.; Staskawicz, B. J.; Cho, M.-J.; Rokhsar, D. S.; Lyons, J. B.
10.1101/2021.10.08.462827 — plant biology — Posted on 2021-10-08
3126 Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals
Guerrero-Juarez, C.; Lee, G.; Liu, Y.; Wang, S.; Sha, Y.; Chow, R.; Nguyen, T.; Aasi, S.; Karikomi, M.; Drummond, M.; Nie, Q.; Sarin, K.; Atwood, S. X.
10.1101/2021.10.07.463571 — cancer biology — Posted on 2021-10-08
3128 Membrane fission during bacterial spore development requires DNA-driven cellular inflation
Landajuela, A.; Braun, M.; Martinez-Calvo, A.; Rodrigues, C. D. A.; Doan, T.; Rudner, D. Z.; Wingreen, N. S.; Karatekin, E.
10.1101/2021.10.08.463650 — biophysics — Posted on 2021-10-08
3132 Extreme hot weather has stronger impacts on avian reproduction in forests than in cities
Pipoly, I.; Preiszner, B.; Sandor, K.; Sinkovics, C.; Seress, G.; Vincze, E.; Bokony, V.; Liker, A.
10.1101/2020.01.29.924332 — ecology — Posted on 2021-10-08
3133 Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes
Christensen, J. R.; Kendrick, A. A.; Troung, J. B.; Aguilar-Maldonado, A.; Adani, V.; Dzieciatkowska, M.; Reck-Peterson, S. L.
10.1101/2021.10.07.463551 — cell biology — Posted on 2021-10-08
3135 A Systematic Interrogation of MHC Class I Antigen Presentation Identifies Constitutive and Compensatory Protein Degradation Pathways
Mamrosh, J. L.; Li, J.; Sherman, D. J.; Moradian, A.; Sweredoski, M. J.; Verma, R.; Johnston, J. A.; Lipford, J. R.; Deshaies, R. J.
10.1101/2021.10.07.463289 — molecular biology — Posted on 2021-10-08
3136 Impairment of the cellulose degradation machinery enhances fungal virulence but limits reproductive fitness
Gamez-Arjona, F. M.; Vitale, S.; Voxeur, A.; Dora, S.; Mueller, S.; Sancho-Andres, G.; Montesinos, J. C.; Di Pietro, A.; Sanchez-Rodriguez, C.
10.1101/2021.10.08.463612 — microbiology — Posted on 2021-10-08
3138 Exo-enzymatic addition of diazirine-modified sialic acid to cell surfaces enables photocrosslinking of glycoproteins
Yarravarapu, N.; Konada, R. S. R.; Darabedian, N.; Pedowtiz, N. J.; Krishnamurthy, S. N.; Pratt, M. R.; Kohler, J. J.
10.1101/2021.10.07.463072 — biochemistry — Posted on 2021-10-08
3139 Multi-omics analysis of multiple glucose-sensing receptor systems in yeast
Li, S.; Li, Y.; Rushing, B. R.; Harris, S. E.; McRitchie, S. L.; Dominguez, D.; Sumner, S. J.; Dohlman, H. G.
10.1101/2021.10.07.463466 — genomics — Posted on 2021-10-08
3143 Novelty detection in early olfactory processing of the honey bee, Apis mellifera
Lei, H.; Haney, S.; Jernigan, C. M.; Cook, C.; Guo, X.; Smith, B.; Bazhenov, M.
10.1101/2021.10.06.463371 — neuroscience — Posted on 2021-10-08
3149 Identification of sex chromosomes using genomic and cytogenetic methods in a range-expanding spider, Argiope bruennichi (Araneae: Araneidae)
Sheffer, M. M.; Cordellier, M. M.; Forman, M.; Grewoldt, M.; Hoffmann, K.; Jensen, C.; Kotz, M.; Kral, J.; Kuss, A. W.; Liznarova, E.; Uhl, G.
10.1101/2021.10.06.463373 — genetics — Posted on 2021-10-08
3155 Somnotate: A robust automated sleep stage classifier that exceeds human performance and identifies ambiguous states in mice
Brodersen, P. J. N.; Alfonsa, H.; Krone, L. B.; Blanco-Duque, C.; Fisk, A. S.; Flaherty, S. J.; Guillaumin, M. C. C.; Huang, Y.-G.; Kahn, M. C.; McKillop, L. E.; Milinski, L.; Taylor, L.; Thomas, C. W.; Yamagata, T.; Vyazovskiy, V. V.; Akerman, C. J.
10.1101/2021.10.06.463356 — neuroscience — Posted on 2021-10-08
3157 Harmoni: a Method for Eliminating Spurious Interactions due to the Harmonic Components in Neuronal Data
Jamshidi Idaji, M.; Zhang, J.; Stephani, T.; Nolte, G.; Mueller, K.-R.; Villringer, A.; Nikulin, V.
10.1101/2021.10.06.463319 — neuroscience — Posted on 2021-10-08
3158 Aberrant Functional Connectivity between Reward and Inhibitory Control Networks in Pre-Adolescent Binge Eating Disorder
Murray, S.; Alba, C.; Duval, C.; Nagata, J.; Cabeen, R.; Lee, D.; Toga, A. W.; Siegel, S.; Jann, K.
10.1101/2021.10.06.463386 — neuroscience — Posted on 2021-10-08
3159 Cell Stiffening Contributes to Complement-mediated Injury of Choroidal Endothelial Cells in Early AMD
Cabrera, A. P.; Stoddard, J.; Tierno, I. S.; Matisioudis, N.; Agarwal, M.; Renner, L.; Palegar, N.; Neuringer, M.; McGill, T. J.; Ghosh, K.
10.1101/2021.10.06.463274 — pathology — Posted on 2021-10-08
3161 An integrative omics approach reveals posttranscriptional mechanisms underlying circadian temperature compensation
Schmal, C.; Maier, B.; Ashwal-Fluss, R.; Bartok, O.; Finger, A.-M.; Bange, T.; Koutsouli, S.; Robles, M. S.; Kadener, S.; Herzel, H.; Kramer, A.
10.1101/2021.10.06.463236 — genomics — Posted on 2021-10-08
3165 Inhibition of SARS-CoV-2 spike protein palmitoylation reduces virus infectivity
Ramadan, A. A.; Mayilsamy, K.; McGill, A. R.; Ghosh, A.; Giulianotti, M. A.; Donow, H. M.; Mohapatra, S. S.; Mohapatra, S.; Chandran, B.; Deschenes, R. J.; Roy, A.
10.1101/2021.10.07.463402 — molecular biology — Posted on 2021-10-08
3167 Non-invasive Imaging of Sense of Smell by Tracking the Voltage-Gated Sodium Channel NaV1.7
Adilbay, D.; Gonzales, J.; Demetrio de Souza Franca, P.; Roberts, S.; Patel, S.; Viray, T.; Chow, C. Y.; King, G. F.; Jain, S. K.; Ordonez, A. A.; Caroll, L. S.; Pillarsetty, N.; Reiner, T.
10.1101/2021.10.07.463532 — neuroscience — Posted on 2021-10-08
3168 Compositional analysis of Sindbis virus ribonucleoproteins reveals an extensive co-opting of key nuclear RNA-binding proteins
Kamel, W.; Ruscica, V.; Garcia-Moreno, M.; Palmalux, N.; Iselin, L.; Hannan, M.; Järvelin, A.; Noerenberg, M.; Moore, S.; Merits, A.; Davis, I.; Martinez, J.; Mohammed, S.; Castello, A.
10.1101/2021.10.06.463336 — microbiology — Posted on 2021-10-08
3169 Simultaneous Mnemonic and Predictive Representations in the Auditory Cortex
Cappotto, D.; Auksztulewicz, R.; Kang, H.; Li, K.; Melloni, L.; Schnupp, J.
10.1101/2021.10.08.463638 — neuroscience — Posted on 2021-10-08
3174 Low dose pig anti-influenza virus monoclonal antibodies reduce lung pathology but do not prevent virus shedding
Paudyal, B.; McNee, A.; Rijal, P.; Carr, B. V.; Nunez, A.; McCauley, J. W.; Daniels, R. S.; Townsend, A. R.; Hammond, J. A.; Tchilian, E.
10.1101/2021.10.08.463636 — immunology — Posted on 2021-10-08
3177 Evolution of chlorophyll degradation is associated with plant transition to land
Schumacher, I.; Menghini, D.; Ovinnikov, S.; Hauenstein, M.; Fankhauser, N.; Zipfel, C.; Aubry, S.
10.1101/2021.10.07.463469 — plant biology — Posted on 2021-10-08
3180 Mutation rate dynamics reflect ecological change in an emerging zoonotic pathogen
Murray, G.; Balmer, A. J.; Herbert, J.; Hadijirn, N. F.; Kemp, C. L.; Matuszewska, M.; Bruchmann, S.; Hossain, A. S. M. M.; Gottschalk, M.; Tucker, A. W.; Miller, E.; Weinert, L. A.
10.1101/2021.04.12.439332 — evolutionary biology — Posted on 2021-10-08
3181 Osteosarcoma tumors maintain intra-tumoral heterogeneity, even while adapting to environmental pressures that drive clonal selection
Rajan, S.; McAloney, C. A.; Vetter, T. A.; Cam, M.; Gross, A. C.; Taslim, C.; Wang, M.; Cannon, M. V.; Oles, A.; Franz, E.; Flanigan, K. M.; Roberts, R. D.
10.1101/2020.11.03.367342 — cancer biology — Posted on 2021-10-08
3184 Population Structure of Nation-wide Rice in Thailand
Vejchasarn, P.; Shearman, J. R.; Chaiprom, U.; Phansenee, Y.; Suthanthangjai, A.; Jairin, J.; Chamarerk, V.; Tulyananda, T.; Amornbunchornvej, C.
10.1101/2021.05.09.443284 — genetics — Posted on 2021-10-08
3185 The origins and drivers of Neotropical diversity
Meseguer, A. S.; Michel, A.; Fabre, P.-H.; Perez-Escobar, O.; Chomicki, G.; Riina, R.; Antonelli, A.; Antoine, P.-O.; Delsuc, F.; Condamine, F.
10.1101/2021.02.24.432517 — evolutionary biology — Posted on 2021-10-08
3186 Sleep spindle frequency: overnight dynamics, afternoon nap effects, and possible circadian modulation
Bodizs, R.; Horvath, C. G.; Szalardy, O.; Ujma, P. P.; Simor, P.; Gombos, F.; Kovacs, I.; Genzel, L.; Dresler, M.
10.1101/2021.06.28.450146 — neuroscience — Posted on 2021-10-08
3188 MYB insufficiency disrupts proteostasis in hematopoietic stem cells leading to age-related neoplasia
Clarke, M. L.; Lemma, R. B.; Walton, D. S.; Volpe, G.; Noyvert, B.; Gabrielsen, O. S.; Frampton, J.
10.1101/2021.09.04.458970 — cancer biology — Posted on 2021-10-08
3191 HIGHER VIRAL VIRULENCE SELECTS FOR FASTER EVOLUTION OF HOST RESISTANCE
Wendling, C. C.; Lange, J.; Liesegang, H.; Sieber, M.; Poehlein, A.; Bunk, B.; Reikov, J.; Goehlich, H.; Roth, O.; Brockhurst, M.
10.1101/2021.03.26.437141 — evolutionary biology — Posted on 2021-10-08
3193 Fluorescence exclusion: a rapid, accurate and powerful method for measuring yeast cell volume
Garcia-Ruano, D.; Jain, A.; Ryan, J. C.; Balasubramaniam, V. R.; Venkova, L.; Piel, M.; Coudreuse, D.
10.1101/2021.10.07.463508 — cell biology — Posted on 2021-10-08
3197 Identification of a novel modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast
Sing, C. N.; Garcia, E. J.; Lipkin, T.; Huckaba, T.; Tsang, C. A.; Coughlin, A.; Yang, E. J.; Boldogh, I. R.; Higuchi-Sanabria, R.; Pon, L.
10.1101/2021.10.07.463535 — cell biology — Posted on 2021-10-07
3198 Screening coffee genotypes for Cercospora coffeicola resistance in Brazil
Ramos, J. B.; Resende, M. L. V. d.; Botelho, D. M. d. S.; Pereira, R. C. M.; Reichel, T.; Balieiro, A. A. F.; Botega, G. P.; Resende, J. C. d.
10.1101/2021.10.07.463543 — plant biology — Posted on 2021-10-07
3200 Leptospira surface protein LigA plays a multifaceted role in modulating the host innate immune response
Kumar, A.; Varma, V. P.; Sridhar, K.; Abdullah, M.; Vyas, P.; Ashiq, M.; Chang, Y.-F.; Faisal, S. M.
10.1101/2020.10.12.329177 — immunology — Posted on 2021-10-07
3202 Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice
Matsuo, I.; Kawamura, N.; Ohnuki, Y.; Suita, K.; Ishikawa, M.; Matsubara, T.; Mototani, Y.; Ito, A.; Hayakawa, Y.; Nariyama, M.; Morii, A.; Kiyomoto, K.; Tsunoda, M.; Gomi, K.; Okumura, S.
10.1101/2021.10.07.463544 — physiology — Posted on 2021-10-07
3207 Genome assembly of the tayra (Eira barbara, Mustelidae) and comparative genomic analysis reveal adaptive genetic variation in the subfamily Guloninae
Derezanin, L.; Blazyte, A.; Dobrynin, P.; Duchene, D. A.; Grau, J. H.; Jeon, S.; Kliver, S.; Koepfli, K.-P.; Meneghini, D.; Preick, M.; Tomarovsky, A.; Totikov, A.; Fickel, J.; Förster, D. W.
10.1101/2021.09.27.461651 — evolutionary biology — Posted on 2021-10-07
3209 Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice
Wu, K.; Choi, A.; Koch, M.; Elbashir, S.; Ma, L.; Lee, D.; Woods, A.; Henry, C.; Palandjian, C.; Hill, A.; Jani, H.; Quinones, J.; Nunna, N.; O'Connell, S.; McDermott, A. B.; Falcone, S.; Narayanan, E.; Colpitts, T.; Bennett, H.; Corbett, K.; Seder, R.; Graham, B. S.; Stewart-Jones, G. B.; Carfi, A.; Edwards, D. K.
10.1101/2021.04.13.439482 — microbiology — Posted on 2021-10-07
3210 Taste Bud Connectome: Implications for Taste Information Processing
Wilson, C. E.; Yang, R.; Lasher, R. S.; Dzowo, Y.; Kinnamon, J. C.; Finger, T. E.
10.1101/2021.04.20.440689 — neuroscience — Posted on 2021-10-07
3214 CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
Conners, R.; McLaren, M.; Lapinska, U.; Sanders, K.; Stone, M. R. L.; Blaskovich, M. A. T.; Pagliara, S.; Daum, B.; Rakonjac, J.; Gold, V. A. M.
10.1101/2021.07.20.453082 — biophysics — Posted on 2021-10-07
3215 Sensitive and specific spectral library searching with COSS and Percolator
Shiferaw, G. A.; Gabriels, R.; Bouwmeester, R.; Van Den Bossche, T.; Vandermarliere, E.; Martens, L.; Volders, P.-J.
10.1101/2021.04.09.438700 — bioinformatics — Posted on 2021-10-07
3216 BioKIT: a versatile toolkit for processing and analyzing diverse types of sequence data
Steenwyk, J. L.; Buida, T. J.; Goncalves, C.; Goltz, D. C.; Morales, G. H.; Mead, M. E.; LaBella, A. L.; Chavez, C. M.; Schmitz, J. E.; Hadjifrangiskou, M.; Li, Y.; Rokas, A.
10.1101/2021.10.02.462868 — bioinformatics — Posted on 2021-10-07
3217 Modular Fluorescent Nanoparticle DNA Probes for Detection of Peptides and Proteins
Stawicki, C. M.; Rinker, T. E.; Burns, M.; Tonapi, S. S.; Galimidi, R. P.; Anumala, D.; Robinson, J. K.; Klein, J. S.; Mallick, P.
10.1101/2021.07.30.454524 — bioengineering — Posted on 2021-10-07
3226 A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an AAV hACE2 Mouse Model and non-human primates
Guirakhoo, F.; Kuo, L.; Peng, J.; Huang, J. H.; Kuo, B.; Lin, F.; Liu, Y.-J.; Liu, Z.; Wu, G.; Ding, S.; Hou, K.-L.; Cheng, J.; Yang, V.; Jiang, H.; Wang, J.; Chen, T.; Xia, W.; Lin, E.; Hung, C. H.; Chen, H.-J.; Shih, Z.; Lin, Y.-L.; Wang, S.; Ryan, V.; Schurter, B. T.; Hu, M. M.; Heppner, G.; Malherbe, D. C.; Bukreyev, A.; Hellerstein, M.; Monath, T. P.; Wang, C. Y.
10.1101/2020.11.30.399154 — immunology — Posted on 2021-10-07
3228 A Framework for Brain Atlases: Lessons from seizure Dynamics
Revell, A. Y.; Silva, A. B.; Arnold, T. C.; Stein, J. M.; Das, S. R.; Shinohara, R. T.; Bassett, D. S.; Litt, B.; Davis, K. A.
10.1101/2021.06.11.448063 — neuroscience — Posted on 2021-10-07
3229 AtCGL160 recruits chloroplast coupling factor 1
Reiter, B.; Rosenhammer, L.; Marino, G.; Geimer, S.; Leister, D.; Rühle, T.
10.1101/2021.10.01.462544 — plant biology — Posted on 2021-10-07
3235 Stimulation of the Dorsal Root Ganglion using an Injectrode
Dalrymple, A. N.; Ting, J. E.; Bose, R.; Trevathan, J. K.; Nieuwoudt, S.; Lempka, S. F.; Franke, M.; Ludwig, K. A.; Shoffstall, A.; Fisher, L. E.; Weber, D. J.
10.1101/2021.08.16.456553 — bioengineering — Posted on 2021-10-07
3236 Lamina cribrosa vessel and collagen beam networks are distinct
Waxman, S.; Brazile, B. L.; Yang, B.; Gogola, A. L.; Hua, Y.; Lam, P.; Lee, P.-Y.; Voorhees, A. P.; Rizzo, J. F.; Jakobs, T. C.; Sigal, I. A.
10.1101/2021.10.03.462932 — bioengineering — Posted on 2021-10-07
3240 seRNA PAM-1 regulates skeletal muscle satellite cell activation and aging through trans regulation of Timp2 expression synergistically with Ddx5
So, K. K. H.; Huang, Y.; Zhang, S.; He, L.; Li, Y.; Chen, X.; Zhao, Y.; Ding, Y.; Zhou, J.; Yuan, J.; Sham, M. H.; Sun, H.; Wang, H.
10.1101/2021.10.06.463443 — developmental biology — Posted on 2021-10-07
3242 Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switching and cofilin dependent podosome formation
Swiatlowska, P.; Sit, B.; Feng, Z.; Marhuenda, E.; Xanthis, I.; Zingaro, S.; Ward, M.; Zhou, X.; Xiao, Q.; Shanahan, C.; Jones, G.; Yu, C.-h.; Iskratsch, T.
10.1101/2020.12.27.424498 — cell biology — Posted on 2021-10-07
3243 Models of the cardiac L-type calcium current: a quantitative comparison
Agrawal, A.; Wang, K.; Polonchuk, L.; Cooper, J.; Mirams, G. R.; Gavaghan, D. J.; Clerx, M.
10.1101/2021.10.04.462988 — cell biology — Posted on 2021-10-07
3244 Human Beta Cell Mass Expansion In Vivo With A Harmine and Exendin-4 Combination: Quantification and Visualization By iDISCO+ 3D Imaging
Rosselot, C.; Alvarsson, A.; Wang, P.; Li, Y.; Beliard, K.; Lu, G.; Li, R.; Liu, H.; Gillespie, V.; Tzavaras, N.; Kumar, K.; DeVita, R. J.; Stewart, A. F.; Stanley, S. A.; Garcia-Ocana, A.
10.1101/2020.07.24.220244 — cell biology — Posted on 2021-10-07
3245 Heat Stress Regulates the Expression of TPK1 Gene at Transcriptional and Post-Transcriptional Levels in Saccharomyces cerevisiae
Canononero, L.; Pautasso, C.; Galello, F.; Sigaut, L.; Pietrasanta, L.; Nombela, F. J. A.; Bermudez Moretti, M.; Portela, P.; Rossi, S.
10.1101/2021.10.07.463258 — molecular biology — Posted on 2021-10-07
3246 Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction
Scheithauer, T. P. M.; Herrema, H.; YU, H. B.; Bakker, G. J.; Winkelmeijer, M.; Soukhatcheva, G.; Dai, D.; Ma, C.; Havik, S. R.; Balvers, M.; Davids, M.; Meijnikman, A. S.; Aydin, O.; van den Born, B.-J. H.; Besselink, M. G.; Busch, O. R.; de Brauw, M.; van de Laar, A.; Belzer, C.; Stahl, M.; de Vos, W.; Vallance, B. A.; Nieuwdorp, M.; Verchere, C. B.; van Raalte, D. H.
10.1101/2021.10.07.463317 — molecular biology — Posted on 2021-10-07
3247 Genomic and phenotypic characterization of Pseudomonas hygromyciniae, a novel bacterial species discovered from a commercially purchased antibiotic
Turner, T. L.; Mitra, S. D.; Kochan, T. J.; Pincus, N. B.; Corbin, M. L.; Cheung, B.; Gatesy, S. W.; Afzal, T.; Ozer, E. A.; Hauser, A. R.
10.1101/2021.10.06.463447 — microbiology — Posted on 2021-10-07
3248 Genomic and antigenic diversity of carried Klebsiella pneumoniae isolates mirrors that of invasive isolates in Blantyre, Malawi
Lewis, J. M.; Mphasa, M.; Banda, R.; Beale, M. A.; Mallewa, J.; Heinz, E.; Thomson, N. R.; Feasey, N. A.
10.1101/2021.10.07.463515 — microbiology — Posted on 2021-10-07
3250 PBP1 of Staphylococcus aureus has multiple essential functions in cell division
Wacnik, K.; Rao, V. A.; Chen, X.; Lafage, L.; Pazos, M.; Booth, S.; Vollmer, W.; Hobbs, J. K.; Lewis, R. J.; Foster, S. J.
10.1101/2021.10.07.463504 — microbiology — Posted on 2021-10-07
3251 Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks
Amato, K. A.; Haddock, L. A.; Braun, K. M.; Meliopoulos, V.; Livingston, B.; Honce, R.; Schaack, G. A.; Boehm, E.; Higgins, C. A.; Barry, G. L.; Koelle, K.; Schultz-Cherry, S.; Friedrich, T. C.; Mehle, A.
10.1101/2021.09.28.462198 — microbiology — Posted on 2021-10-07
3252 A Diversity Outbred F1 mouse model identifies host-intrinsic genetic regulators of response to immune checkpoint inhibitors
HACKETT, J. B.; Glassbrook, J. E.; McCasland, J.; Muniz, M. C.; Movahhedin, N.; McCarthy-Leo, C. E.; Dyson, G.; Gibson, H. M.
10.1101/2021.10.07.463570 — immunology — Posted on 2021-10-07
3253 Increased connectivity among sensory and motor regions during visual and audiovisual speech perception
Peelle, J. E.; Spehar, B.; Jones, M. S.; McConkey, S.; Myerson, J.; Hale, S.; Sommers, M. S.; Tye-Murray, N.
10.1101/2020.12.15.422726 — neuroscience — Posted on 2021-10-07
3254 Sonogenetic control of mammalian cells using exogenous Transient Receptor Potential A1 channels
Duque, M.; Lee-Kubli, C.; Tufail, Y.; Magaram, U.; Patel, J.; Chakraborty, A.; Lopez, J. M.; Edsinger, E.; Vasan, A.; Shiao, R.; Weiss, C.; Friend, J.; Chalasani, S. H.
10.1101/2020.10.14.338699 — neuroscience — Posted on 2021-10-07
3256 Regulation of drought tolerance in Arabidopsis involves PLATZ4-mediated transcriptional suppression of PIP2;8
Liu, M.; Wang, C.; Ji, Z.; Zhang, L.; Li, C.; Huang, J.; Yang, G.; Yan, K.; Zhang, S.; Zheng, C.; Wu, C.
10.1101/2021.10.06.463369 — plant biology — Posted on 2021-10-07
3258 INTRINSIC MOTOR NEURONE EXCITABILITY IS REDUCED IN SOLEUS AND TIBIALIS ANTERIOR OF OLDER ADULTS
Orssatto, L. B. R.; Borg, D. N.; Blazevich, A. J.; Sakugawa, R. L.; Shield, A. J.; Trajano, G. S.
10.1101/2021.06.23.449552 — physiology — Posted on 2021-10-07
3259 MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer
Acon, M. S.; Geiss, C.; Torres-Calvo, J.; Bravo-Estupinan, D.; Oviedo, G.; Arias-Arias, J. L.; Rojas-Matey, L. A.; Baez, E.; Vasquez-Vargas, G.; Oses-Vargas, Y.; Guevara-Coto, J.; Segura-Castillo, A.; Siles-Canales, F.; Quiros-Barrantes, S.; Regnier-Vigouroux, A.; Mendes, P.; Mora-Rodriguez, R. M.
10.1101/2021.04.20.440572 — cancer biology — Posted on 2021-10-07
3261 Entropy Regularized Deconvolution of Cellular Cryo-Transmission Electron Tomograms
Croxford, M.; Elbaum, M.; Arigovindan, M.; Kam, Z.; Agard, D. A.; Villa, E.; Sedat, J.
10.1101/2021.04.26.441469 — biophysics — Posted on 2021-10-07
3262 CRISPR-mediated insertion of a chimeric antigen receptor produces nonviral T cell products capable of inducing solid tumor regression
Mueller, K.; Piscopo, N.; Forsberg, M.; Saraspe, L.; Das, A.; Russell, B.; Smerchansky, M.; Shi, L.; Ali, A.; Lazzarotto, C.; Tsai, S.; Capitini, C. M.; Saha, K.
10.1101/2021.08.06.455489 — bioengineering — Posted on 2021-10-07
3263 Engineered endosymbionts capable of directing mammalian cell gene expression
Madsen, C. S.; Makela, A. V.; Greeson, E. M.; Hardy, J. W.; Contag, C. H.
10.1101/2021.10.05.463266 — bioengineering — Posted on 2021-10-07
3274 Genomic and metabolic adaptations of biofilms to ecological windows of opportunities in glacier-fed streams
Busi, S. B.; Bourquin, M.; Fodelianakis, S.; Michoud, G.; Kohler, T. J.; Peter, H.; Pramateftaki, P.; Styllas, M.; Tolosano, M.; De Staercke, V.; Schon, M.; de Nies, L.; Marasco, R.; Daffonchio, D.; Ezzat, L.; Wilmes, P.; Battin, T. J.
10.1101/2021.10.07.463499 — microbiology — Posted on 2021-10-07
3279 Minimal required exposures reveal the primacy of awareness in human face perception
Lanfranco, R. C.; Canales-Johnson, A.; Cleeremans, A.; Rabagliati, H.; Carmel, D.
10.1101/2021.10.06.462913 — neuroscience — Posted on 2021-10-07
3280 High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain
Dasovich, M. A.; Zhou, J.; Thomas, A. G.; Goodman, J. A.; McPherson, R. L.; Jayabalan, A. K.; Busa, V. F.; Cheng, S.-J.; Murphy, B.; Redinger, K. R.; Tsukamoto, T.; Slusher, B. S.; Bosch, J.; Wei, J.; Leung, A.
10.1101/2021.10.07.463234 — biochemistry — Posted on 2021-10-07
3293 Dwarf-shrubs dynamics in Mediterranean high mountain ecosystems
De Toma, A.; Carboni, M.; Bazzichetto, M.; Malavasi, M.; Cutini, M.
10.1101/2021.10.06.463306 — ecology — Posted on 2021-10-07
3297 The Endosomal pH Regulator NHE9 is a Driver of Stemness in Glioblastoma
Ko, M.; Makena, M. R.; Schiapparelli, P. V.; Suarez Meade, P.; Mekile, A. X.; Lal, B.; Lopez-Bertoni, H.; Laterra, J.; Quinones-Hinojosa, A.; Rao, R.
10.1101/2021.10.07.463493 — cancer biology — Posted on 2021-10-07
3298 Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance
Mindell, J. A.; Leray, X.; Hilton, J. K.; Nwangwu, K.; Becerril, A.; Mikusevic, V.; Fitzgerald, G.; Amin, A.; Weston, M. R.
10.1101/2021.10.07.463477 — biophysics — Posted on 2021-10-07
3301 Fluorescence exclusion: a rapid, accurate and powerful method for measuring yeast cell volume
Garcia-Ruano, D.; Jain, A.; Ryan, J. C.; Balasubramaniam, V. R.; Venkova, L.; Piel, M.; Coudreuse, D.
10.1101/2021.10.07.463508 — cell biology — Posted on 2021-10-07
3302 Proteome-wide landscape of solubility limits in a bacterial cell
Gyorkei, A.; Papp, B.; Daruka, L.; Balogh, D.; Oszi, E.; Magyar, Z.; Szappanos, B.; Fekete, G.; Fuxreiter, M.; Horvath, P.; Pal, C.; Kintses, B.
10.1101/2021.10.05.463219 — molecular biology — Posted on 2021-10-07
3304 Evaluation of flow cytometry for cell count and detection of bacteria in biological fluids.
DOSSOU, N. C.; GAUBERT, I.; MORICEAU, C.; CORNET, E.; LE HELLO, S.; MALANDAIN, D.
10.1101/2021.10.04.463144 — microbiology — Posted on 2021-10-07
3305 Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein after infection and/or vaccination
Garrett, M. E.; Galloway, J. G.; Wolf, C.; Logue, J. K.; Franko, N.; Chu, H. Y.; Matsen, F.; Overbaugh, J. M.
10.1101/2021.10.05.463210 — immunology — Posted on 2021-10-07
3306 Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6-dependent pathway
Wiegreffe, C.; Wahl, T.; Natalie, J. S.; Bonnefont, J.; Vanderhaeghen, P.; Liu, P.; Britsch, S.
10.1101/2021.10.06.463323 — neuroscience — Posted on 2021-10-07
3308 Geosmin suppresses defensive behaviour and elicits unusual neural responses in honey bees.
Scarano, F.; Deivarajan Suresh, M.; Tiraboschi, E.; Cabirol, A.; Nouvian, M.; Nowotny, T.; Haase, A.
10.1101/2021.10.06.463314 — neuroscience — Posted on 2021-10-07
3311 Global Dynamics as Communication Sensors in Peptide Synthetase Cyclization Domains.
Mishra, S. H.; Kancherla, A. K.; Marincin, K. A.; Bouvignies, G.; Nerli, S.; Sgourakis, N.; Dowling, D. P.; Frueh, D. P.
10.1101/2021.10.06.461881 — biophysics — Posted on 2021-10-07
3312 Tracking the fates of iron-labeled tumor cells in vivo using Magnetic Particle Imaging
Makela, A. V.; Schott, M. A.; Sehl, O. C.; Gevaert, J. J.; Foster, P. J.; Contag, C. H.
10.1101/2021.10.06.463387 — biophysics — Posted on 2021-10-07
3316 The role of evolutionary modes for trait-based cascades in mutualistic networks
Bastazini, V. A. G.; Debastiani, V.; Cappelatti, L.; Guimaraes, P.; Pillar, V. D. P.
10.1101/2021.10.05.462726 — ecology — Posted on 2021-10-07
3317 The translational landscape of SARS-CoV-2 and infected cells
Puray-Chavez, M.; Tenneti, K.; Lee, N.; Wang, Y.; Vuong, H. R.; Liu, Y.; Horani, A.; Huang, T.; Gunsten, S. P.; Case, J. B.; Yang, W.; Diamond, M. S.; Brody, S. L.; Dougherty, J.; Kutluay, S. B.
10.1101/2020.11.03.367516 — microbiology — Posted on 2021-10-07
3319 Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpes Infection
Dhanushkodi, N.; Prakash, S.; Srivastava, R.; Coulon, P.-G.; Arellano, D.; Kapadia, R. V.; Fahim, R.; Suzer, B.; Jamal, L.; BenMohamed, L.
10.1101/2021.10.05.463293 — immunology — Posted on 2021-10-07
3326 Systematic identification of intron retention associated variants from massive publicly available transcriptome sequencing data
Shiraishi, Y.; Okada, A.; Chiba, K.; Omori, I.; Mateos, R. N.; Iida, N.; Yamauchi, H.; Kosaki, K.; Yoshimi, A.
10.1101/2021.10.05.463278 — bioinformatics — Posted on 2021-10-07
3328 The effects of age, sex, weight and breed on canid methylomes
Rubbi, L.; Zhang, H.; Feng, J.; He, C.; Kurnia, P.; Ratan, P.; Tammana, A.; Thompson, M.; Stahler, D.; Ostrander, E. A.; vonHoldt, B.; Pellegrini, M.
10.1101/2021.10.05.463246 — bioinformatics — Posted on 2021-10-07
3333 Transcriptomic, epigenetic and metabolic characterization of the pluripotency continuum in rabbit preimplantation embryos
Bouchereau, W.; Jouneau, L.; Archilla, C.; Aksoy, I.; Moulin, A.; Daniel, N.; Peynot, N.; Calderari, S.; Joly, T.; Godet, M.; Jaszczyszyn, Y.; Pratlong, M.; Severac, D.; Savatier, P.; Duranthon, V.; Afanassieff, M.; Beaujean, N.
10.1101/2021.10.06.463389 — developmental biology — Posted on 2021-10-07
3335 Immunodominant and neutralizing linear B cell epitopes spanning the spike and membrane proteins of Porcine Epidemic Diarrhea Virus
Polyiam, K.; Ruengjitchatchawalya, M.; Mekvichitsaeng, P.; Kaeoket, K.; Hoonsuwan, T.; Joiphaeng, P.; Roshorm, Y. M.
10.1101/2021.10.05.463270 — immunology — Posted on 2021-10-07
3340 Neural networks implicated in autobiographical memory training
Cirneci, D.; Onu, M.; Papasteri, C. C.; Georgescu, D. P.; Poalelungi, C.; Sofonea, A.; Puscasu, N.; Podina, I. R.; Berceanu, A. I.; Carcea, I.
10.1101/2021.10.05.463255 — neuroscience — Posted on 2021-10-07
3341 Fronto-parietal Network Segregation Predicts Maintained Cognition in the Cognitively Healthy Oldest-old (85+): evidence for dedifferentiation
Sims, S. A.; Faulkner, M. E.; Stewart, P.; Merritt, S.; Rezaei, R. F.; Bharadwaj, P. K.; Franchetti, M. K.; Raichlen, D. A.; Jessup, C. J.; Hishaw, G. A.; Van Etten, E. J.; Trouard, T. P.; Geldmacher, D.; Wadley, V. G.; Alperin, N.; Porges, E. S.; Woods, A. J.; Cohen, R. A.; Levin, B. E.; Rundek, T.; Alexander, G. E.; Visscher, K. M.
10.1101/2021.10.05.463207 — neuroscience — Posted on 2021-10-07
3342 Multifunctional Cre-dependent transgenic mice for high-precision all-optical interrogation of neural circuits
Bounds, H. A.; Sadahiro, M.; Hendricks, W. D.; Gajowa, M.; Oldenburg, I. A.; Gopakumar, K.; Quintana, D.; Daigle, T.; Zeng, H.; Adesnik, H.
10.1101/2021.10.05.463223 — neuroscience — Posted on 2021-10-07
3345 Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy
Wu, K.-X.; Yeo, N. J. Y.; Ng, C.-Y.; Chioh, F. W. J.; Fan, Q.; Tian, X.; Yang, B.; Narayanan, G.; Tay, H. M.; Hou, H. W.; Dunn, R. N.; Su, X.; Cheung, C. M. G.; Cheung, C.
10.1101/2021.10.06.463357 — cell biology — Posted on 2021-10-07
3347 An innovative optical context to make honeybees crash repeatedly
Serres, J. R.; Morice, A. H.; Blary, C.; Miot, R.; Montagne, G.; Ruffier, F.
10.1101/2021.09.23.461476 — animal behavior and cognition — Posted on 2021-10-07
3350 A cross biomes bacterial diversity shed light on ocean-atmosphere microbial transmission.
Lang-Yona, N.; Flores, J. M.; Haviv, R.; Alberti, A.; Poulain, J.; Belser, C.; Trainic, M.; Gat, D.; Ruscheweyh, H. J.; Wincker, P.; Sunagawa, S.; Rudich, Y.; Koren, I.; Vardi, A.
10.1101/2021.06.06.445733 — ecology — Posted on 2021-10-07
3351 Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption
Cole, B.; Lambrechts, L.; Boyer, Z.; Noppe, Y.; De Scheerder, M.-A.; Eden, J.-S.; Vrancken, B.; Schlub, T.; Frenkel, L. M.; McLaughlin, S.; Palmer, S.; Vandekerckhove, L.
10.1101/2021.02.04.429690 — microbiology — Posted on 2021-10-07
3357 Fine-mapping of nuclear compartments using ultra-deep Hi-C shows that active promoter and enhancer elements localize in the active A compartment even when adjacent sequences do not
Gu, H.; Harris, H.; Olshansky, M.; Eliaz, Y.; Krishna, A.; Kalluchi, A.; Jacobs, M.; Cauer, G.; Pham, M.; Rao, S. S. P.; Dudchenko, O.; Omer, A.; Mohajeri, K.; Kim, S.; Nichols, M. H.; Davis, E. S.; Udupa, D.; Presser Aiden, A.; Corces, V. G.; Phanstiel, D. H.; Noble, W. S.; Seo, J.-S.; Talkowski, M. E.; Aiden, E. L.; Rowley, M. J.
10.1101/2021.10.03.462599 — genomics — Posted on 2021-10-06
3361 Intercellular transport of RNA can limit heritable epigenetic changes
Shugarts, N.; Yi, A. L.; Chan, W. M.; Marre, J. A.; Sathya, A.; Jose, A. M.
10.1101/2021.10.05.463267 — genetics — Posted on 2021-10-06
3363 Highly concentrated trehalose induces transient senescence-associated secretory phenotype in fibroblasts via CDKN1A/p21
Muto, J.; Fukuda, S.; Watanabe, K.; Dai, X.; Tsuda, T.; Kiyoi, T.; Mori, H.; Shiraishi, K.; Murakami, M.; Higashiyama, S.; Mizukami, Y.; Sayama, K.
10.1101/2021.10.06.463325 — cell biology — Posted on 2021-10-06
3365 In situ structures of membrane-assisted assembly and selective autophagy of enteroviruses
Dahmane, S.; Kerviel, A.; Morado, D. R.; Shankar, K.; Ahlman, B.; Lazarou, M.; Altan-Bonnet, N.; Carlson, L.-A.
10.1101/2021.10.06.463375 — microbiology — Posted on 2021-10-06
3366 Cryo-sensitive aggregation triggers NLRP3 inflammasome assemblyin cryopyrin-associated periodic syndrome
Karasawa, T.; Komada, T.; Yamada, N.; Aizawa, E.; Mizushina, Y.; Watanabe, S.; Baatarjav, C.; Matsumura, T.; Takahashi, M.
10.1101/2021.10.05.463273 — immunology — Posted on 2021-10-06
3368 Trial and error: a hierarchical modeling approach to test-retest assessment
Chen, G.; Pine, D. S.; Brotman, M. A.; Smith, A. R.; Cox, R. W.; Haller, S. P.
10.1101/2021.01.04.425305 — neuroscience — Posted on 2021-10-06
3371 BET inhibitors synergize with anti-PD1 by rescuing TCF1+ progenitor exhausted CD8+ T cells in Acute Myeloid Leukemia
Romine, K. A.; Cho, H. J.; Kosaka, Y.; Byrd, K. H.; Coy, J. L.; Flynn, P. A.; Newman, M. T.; Loo, C.; Scott, J.; Lind, E. F.
10.1101/2021.08.04.455147 — cancer biology — Posted on 2021-10-06
3372 Engineered endosymbionts capable of directing mammalian cell gene expression
Madsen, C. S.; Makela, A. V.; Greeson, E. M.; Hardy, J. W.; Contag, C. H.
10.1101/2021.10.05.463266 — bioengineering — Posted on 2021-10-06
3373 Improved Ultrasound Localization Microscopy based on Microbubble Uncoupling via Transmit Excitation (MUTE)
Kim, J.; Lowerison, M.; Sekaran, N. C.; Kou, Z.; Dong, Z.; Michael, O. L.; Llano, D. A.; Song, P.
10.1101/2021.10.05.463265 — bioengineering — Posted on 2021-10-06
3375 The production of 4,182 mouse lines identifies experimental and biological variables impacting Cas9-mediated mutant mouse line production
Elrick, H.; Peterson, K. A.; Wood, J. A.; Lanza, D. G.; Acar, E. F.; Teboul, L.; Ryder, E. J.; Ayabe, S.; Birling, M.-C.; Caulder, A.; Chiani, F.; Codner, G. F.; Doe, B.; Duddy, G.; Gambadoro, A.; Gertsenstein, M.; Gomez-Segura, A.; Goodwin, L. O.; Ju, C.; Kasparek, P.; King, R. E.; Lee, D.; Lee, H.; Lintott, L. G.; Liu, Z.; Lorenzo, I.; Mackenzie, M.; Marschall, S.; Matthews, P.; Ruhe, M.; Santos, L.; Seavitt, J. R.; Seisenberger, C.; Wardle-Jones, H.; Willis, B. J.; Zhang, J.; Zhao, J.; Zhou, F.; Adams, D. J.; Bradley, A.; Braun, R. E.; DeMayo, F. J.; Dickinson, M. E.; Gao, X.; Herault, Y.;
10.1101/2021.10.06.463037 — genetics — Posted on 2021-10-06
3376 Imbalance between IL-36 receptor agonist and antagonist drives neutrophilic inflammation in COPD
Baker, J. R.; Fenwick, P. S.; Coss, C. K.; Owles, H. B.; Elkin, S. L.; Thomas, M.; Fine, J.; El-Kasmi, K. C.; Barnes, P. J.; Donnelly, L. E.
10.1101/2021.10.06.463311 — cell biology — Posted on 2021-10-06
3378 Models of the cardiac L-type calcium current: a quantitative comparison
Agrawal, A.; Wang, K.; Polonchuk, L.; Cooper, J.; Mirams, G. R.; Gavaghan, D. J.; Clerx, M.
10.1101/2021.10.04.462988 — cell biology — Posted on 2021-10-06
3380 Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response.
Hinman, A. E.; Jani, C.; Pringle, S. C.; Zhang, W. R.; Jain, N.; Martinot, A. J.; Barczak, A. K.
10.1101/2021.10.06.463251 — microbiology — Posted on 2021-10-06
3382 CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation.
Hwang, D.; Ishiwaka, L. L. W.; Boehm, A.; Sahin, Z.; Casella, G.; Jang, S.; Seyedsadr, M.; Gonzalez, M. V.; Garifallou, J. P.; Hakonarson, H.; Zhang, G.-X.; Rostami, A.; Ciric, B.
10.1101/2020.10.23.352534 — immunology — Posted on 2021-10-06
3385 A supervised fingerprint-based strategy to connect natural product mass spectrometry fragmentation data to their biosynthetic gene clusters
Leao, T. F.; Wang, M.; da Silva, R.; van der Hooft, J. J. J.; Bauermeister, A.; Brejnrod, A. D.; Glukhov, E.; Gerwick, L.; Gerwick, W. H.; Bandeira, N.; Dorrestein, P. C.
10.1101/2021.10.05.463235 — bioinformatics — Posted on 2021-10-06
3388 A prebiotic basis for ATP as the universal energy currency
Pinna, S.; Kunz, C.; Harrison, S.; Jordan, S. F.; Ward, J.; Werner, F.; Lane, N.
10.1101/2021.10.06.463298 — biochemistry — Posted on 2021-10-06
3391 Functional analysis of a common BAG3 allele associated with protection from heart failure
Perez-Bermejo, J. A.; Judge, L. M.; Jensen, C. L.; Wu, K.; Truong, A.; Ho, J. J.; Carter, M. A.; Runyon, W. V.; Kaake, R. M.; Pulido, E.; Watry, H. L.; Mandegar, M. A.; Swaney, D. L.; So, P.-L.; Krogan, N. J.; Conklin, B. R.
10.1101/2021.10.06.463213 — genetics — Posted on 2021-10-06
3396 SARS-CoV-2 hijacks neutralizing dimeric IgA for enhanced nasal infection and injury
Zhou, B.; Zhou, R.; Chan, J. F.-W.; Zeng, J.; Zhang, Q.; Yuan, S.; Liu, L.; Robinot, R.; Shan, S.; Ge, J.; Kwong, H. Y.-H.; Zhou, D.; Xu, H.; Chan, C. C.-S.; Poon, V. K.-M.; Chu, H.; Yue, M.; Kwan, K.-Y.; Chan, C.-Y.; Liu, N.; Chan, C. C.-Y.; Chik, K. K.-H.; Du, Z.; Au, K.-K.; Huang, H.; Man, H.-O.; Cao, J.; Li, C.; Wang, Z.; Zhou, J.; Song, Y.; Yeung, M.-L.; To, K. K.-W.; Ho, D. D.; Chakrabarti, L. A.; Wang, X.; Zhang, L.; Yuen, K.-Y.; Chen, Z.
10.1101/2021.10.05.463282 — microbiology — Posted on 2021-10-06
3397 Mice with a humanized immune system are resilient to transplantation of human microbiota
Zhou, W.; Chow, K.-h.; Geyer, R.; Peshkepija, P.; Fleming, E.; Yu, C.; Palucka, K.; Oh, J.
10.1101/2021.10.06.463343 — microbiology — Posted on 2021-10-06
3398 Large-scale comparative genomics unravels great genomic diversity across the Rickettsia and Ca. Megaira genera and identifies Torix group as an evolutionarily distinct clade.
Davison, H. R.; Pilgrim, J.; Wybouw, N.; Parker, J.; Pirro, S.; Hunter-Barnett, S.; Campbell, P. M.; Blow, F.; Darby, A. C.; Hurst, G. D. D.; Siozios, S.
10.1101/2021.10.06.463315 — microbiology — Posted on 2021-10-06
3399 Selective modulation of cell surface proteins during vaccinia infection: implications for immune evasion strategies
Depierreux, D. M.; Altenburg, A. F.; Soday, L.; Fletcher-Etherington, A.; Antrobus, R.; Ferguson, B. J.; Weekes, M. P.; Smith, G. L.
10.1101/2021.10.06.463320 — microbiology — Posted on 2021-10-06
3400 Optimizing the live attenuated influenza A vaccine backbone for high-risk patient groups
Bonifacio, J. P.; Williams, N.; Garnier, L.; Hugues, S.; Schmolke, M.; Mazel-Sanchez, B.
10.1101/2021.10.06.462766 — microbiology — Posted on 2021-10-06
3402 A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition
Gibson, A. R.; Sateriale, A.; Dumaine, J. E.; Engiles, J. B.; Gullicksrud, J. A.; ODea, K.; Doench, J. G.; Beiting, D. P.; Hunter, C. A.; Striepen, B.
10.1101/2021.10.06.463303 — microbiology — Posted on 2021-10-06
3403 Progesterone supplementation in mice leads to microbiome alterations and weight gain in a sex-specific manner
Nuriel-Ohayon, M.; belogolovski, A.; Komissarov, S.; Ben Izhak, M.; Shtossel, O.; Neuman, H.; Ziv, O.; Turjeman, S.; Bel, S.; Louzoun, Y.; Koren, O.
10.1101/2021.10.06.463337 — microbiology — Posted on 2021-10-06
3404 Arginine methylation helps SepIVA balance regulation of septation and elongation in Mycobacterium smegmatis
Freeman, A. M.; Tembiwa, K.; Brenner, J. R.; Chase, M. R.; Fortune, S. M.; Morita, Y. S.; Boutte, C.
10.1101/2021.10.06.463415 — microbiology — Posted on 2021-10-06
3407 The neuropeptide receptor NMUR-1 regulates the specificity of C. elegans innate immunity against pathogen infection
Wibisono, P.; Wibisono, S.; Watteyne, J.; Chen, C.-H.; Sellegounder, D.; Beets, I.; Liu, Y.; Sun, J.
10.1101/2021.05.06.442992 — immunology — Posted on 2021-10-06
3408 High fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner.
Gannon, O. J.; Robison, L. S.; Salinero, A. E.; Abi-Ghanem, C.; Mansour, F. M.; Tyagi, A.; Brawley, R. R.; Ogg, J. D.; Zuloaga, K. L.
10.1101/2021.10.05.463111 — neuroscience — Posted on 2021-10-06
3409 Pan-cancer imaging of TERT expression using deuterium magnetic resonance spectroscopy-based assessment of pyruvate metabolism
Batsios, G.; Taglang, C.; Tran, M.; Stevers, N.; Barger, C.; Gillespie, A. M.; Ronen, S.; Costello, J.; Viswanath, P.
10.1101/2021.10.05.462047 — cancer biology — Posted on 2021-10-06
3413 Immunogenicity of trimetric spike protein associated to Poly(I:C) plus Alum
Santos, J. d.; Cruz, L. F.; Fonseca-Martins, A. M. d.; Maciel, D. O.; Perez, G. G.; Roncaglia-Pereira, V. A.; Dumard, C. H.; Guedes da Silva, F. H.; dos Santos, A. C. V.; Leandro, M. S.; Ferreira, J. R. M.; Pinto, K. G.; Costa, L. J.; Rodrigues, D. A. S.; Silva, M. V. M.; Alvim, R. G. F.; Lima, T. M.; Marsili, F. F.; Abreu, D. P. B. d.; Ferreira, O.; Borges, R. d. S. M.; Tanuri, A.; Souza, T. M. L.; Bergmann, B. R.; Vale, A. M.; Lima, J. S.; de Oliveira, A. C.; Filardy, A. A.; Gomes, A. M. O.; de Matos Guedes, H. L.
10.1101/2021.10.05.461434 — immunology — Posted on 2021-10-06
3414 In vivo reprogramming of murine host immune response genes following Leishmania major infection.
Venugopal, G.; Bird, J. T.; Washam, C. L.; Roys, H.; Bowlin, A.; Byrum, S. D.; Weinkopff, T.
10.1101/2021.10.05.463063 — immunology — Posted on 2021-10-06
3416 Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function
Wu, Q.; Akhter, A.; Pant, S.; Cho, E.; Zhu, J. X.; Garner, A.; Ohyama, T.; Tajkhorshid, E.; van Meyel, D.; Ryan, R. M.
10.1101/2021.10.05.463128 — neuroscience — Posted on 2021-10-06
3417 Single-cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human
Legouis, D.; Rinaldi, A.; Arnoux, G.; Verissimo, T.; Scotti-Gerber, J.; Faivre, A.; Schibler, M.; Rinaldi, A.; Naesens, M.; Koppitch, K.; Pugin, J.; McMahon, A. P.; Moll, S.; de Seigneux, S.; Cippa, P. E.
10.1101/2021.10.05.463150 — pathology — Posted on 2021-10-06
3418 High-content profiling reveals a unified model of copper ionophore dependent cell death in oesophageal adenocarcinoma
Hughes, R. E.; Elliott, R. J.; Li, X.; Munro, A. F.; Makda, A.; Carter, R. N.; Morton, N. M.; Fujihara, K.; Clemons, N. J.; Fitzgerald, R.; O'Neill, J. R.; Hupp, T.; Carragher, N. O.
10.1101/2021.10.05.463189 — cancer biology — Posted on 2021-10-06
3419 Pan-cancer organoid validation of tumor outlier chromosomal amplification events
Salahudeen, A. A.; Yuki, K.; Seoane, J.; Mah, A. T.; Smith, A. R.; Kolahi, K.; De la O, S. M.; Hart, D. J.; Ding, J.; Ma, Z.; Barkal, S. A.; Shukla, N. D.; Zhang, H. C.; Cantrell, M. A.; Batish, A.; Usui, T.; Root, D. E.; Hahn, W.; Curtis, C.; Kuo, C. J.
10.1101/2021.10.05.463147 — cancer biology — Posted on 2021-10-06
3422 RAxML Grove: An empirical Phylogenetic Tree Database
Hoehler, D.; Pfeiffer, W.; Ioannidis, V.; Stockinger, H.; Stamatakis, A.
10.1101/2021.10.05.463179 — bioinformatics — Posted on 2021-10-06
3424 The kinectome: a comprehensive kinematic map of human motion in health and disease
Troisi Lopez, E.; Sorrentino, P.; Liparoti, M.; Minino, R.; Carotenuto, A.; Amico, E.; Sorrentino, G.
10.1101/2021.10.05.463174 — bioengineering — Posted on 2021-10-06
3425 Profiling of mature stage human breastmilk cells identifies host-defense lactocyte sub-populations
Gleeson, J. P.; Chaudhary, N.; Doerfler, R.; Fein, K. C.; Hredzak-Showalter, T.; Whitehead, K. A.
10.1101/2021.10.04.463125 — bioengineering — Posted on 2021-10-06
3427 Optimization of avian perching manoeuvres
KleinHeerenbrink, M.; France, L. A.; Brighton, C. H.; Taylor, G. K.
10.1101/2021.08.28.458019 — animal behavior and cognition — Posted on 2021-10-06
3430 Isotopic signatures induced by upwelling tag regional fish populations in Lake Tanganyika
Ehrenfels, B.; Junker, J.; Namutebi, D.; Callbeck, C. M.; Dinkel, C.; Kalangali, A.; Kimirei, I. A.; Mbonde, A. S.; Mosille, J. B.; Sweke, E. A.; Schubert, C. J.; Seehausen, O.; Wagner, C. E.; Wehrli, B.
10.1101/2021.10.05.463178 — ecology — Posted on 2021-10-06
3432 Transient definitive host presence is sufficient to sustain avian schistosome populations
Rudko, S. P.; McPhail, B. A.; Reimink, R. L.; Froelich, K.; Turnbull, A.; Hanington, P. C.
10.1101/2021.10.05.463157 — ecology — Posted on 2021-10-06
3437 Peptidome profiling for the immunological stratification in sepsis: a proof of concept study
Ledesma, M.; Todero, M. F.; Maceira, L.; Prieto, M.; Vay, C.; Galas, M.; Lopez, B.; Yokobori, N.; Rearte, B.
10.1101/2020.12.29.424724 — immunology — Posted on 2021-10-06
3438 Tuning DO:DM ratios modulates MHC class II immunopeptidomes
Olsson, N. E.; Jiang, W.; Adler, L. N.; Mellins, E.; Elias, J. E.
10.1101/2021.10.05.463141 — immunology — Posted on 2021-10-06
3439 Alterations in excitatory and inhibitory synaptic development within the mesolimbic dopamine pathway in a mouse model of prenatal drug exposure
Boggess, T.; Williamson, J. C.; Niebergall, E. B.; Sexton, H. G.; Mazur, A.; Egleton, R. D.; Grover, L. M.; Risher, W. C.
10.1101/2020.12.18.423503 — neuroscience — Posted on 2021-10-06
3440 Neuromuscular connectomes across development reveal synaptic ordering rules
Meirovitch, Y.; Kang, K.; Draft, R. W.; Pavarino, E. C.; Henao Echeverri, M. F.; Yang, F.; Turney, S. G.; Berger, D. R.; Peleg, A.; Schaleck, R. L.; Lu, J.; Livet, J.; Tapia, J.-C.; Lichtman, J. W.
10.1101/2021.09.20.460480 — neuroscience — Posted on 2021-10-06
3442 A cell-free assay for rapid screening of inhibitors of hACE2-receptor - SARS-CoV-2-Spike binding
Kikuchi, N.; Willinger, O.; Granik, N.; Navon, N.; Ackerman, S.; Samuel, E.; Antman, T.; Katz, N.; Goldberg, S.; Amit, R.
10.1101/2021.10.06.462907 — synthetic biology — Posted on 2021-10-06
3443 A proximal-to-distal survey of healthy adult human small intestine and colon epithelium by single-cell transcriptomics
Burclaff, J.; Bliton, R. J.; Breau, K. A.; Ok, M. T.; Gomez-Martinez, I.; Ranek, J. S.; Bhatt, A. P.; Purvis, J. E.; Woosley, J. T.; Magness, S. T.
10.1101/2021.10.05.460818 — physiology — Posted on 2021-10-06
3445 Hematopoietic stem and progenitor cells integrate Bacteroides-derived innate immune signals to promote gut tissue repair
Hayashi, Y.; Sezaki, M.; Nakato, G.; Biswas, S.; Fakruddin, M.; Morishima, T.; Moon, J.; Ahn, S.; Kim, P.; Miyamoto, Y.; Baba, H.; Fukuda, S.; Takizawa, H.
10.1101/2021.10.05.463122 — pathology — Posted on 2021-10-06
3450 Time-Dependent Image Restoration of Low-SNR Live Cell Ca2+ Fluorescence Microscopy Data
Woelk, L.-M.; Kannabiran, S. A.; Brock, V.; Gee, C. E.; Lohr, C.; Guse, A. H.; Diercks, B.-P.; Werner, R.
10.1101/2021.10.05.462864 — bioinformatics — Posted on 2021-10-06
3452 SARS-CoV-2 causes human BBB injury and neuroinflammation indirectly in a linked organ chip platform
Wang, P.; Jin, L.; Zhang, M.; Wu, Y.; Duan, Z.; Chen, W.; Wang, C.; Liao, Z.; Han, J.; Guo, Y.; Guo, Y.; Wang, Y.; Lai, R.; Qin, J.
10.1101/2021.10.05.463205 — bioengineering — Posted on 2021-10-06
3453 Gigapixel behavioral and neural activity imaging with a novel multi-camera array microscope
Thomson, E.; Harfouche, M.; Konda, P.; Seitz, C. W.; Kim, K.; Cooke, C.; Xu, S.; Blazing, R.; Chen, Y.; Jacobs, W. S.; Park, J.; Dunn, T. W.; Sharma, S.; Horstmeyer, R. W.; Naumann, E. A.
10.1101/2021.10.05.461695 — bioengineering — Posted on 2021-10-06
3455 Large Bi-ethnic Study of Plasma Proteome Leads to Comprehensive Mapping of cis-pQTL and Models for Proteome-wide Association Studies
Zhang, J.; Dutta, D.; Köttgen, A.; Tin, A.; Schlosser, P.; Grams, M. E.; Harvey, B.; CKDGen Consortium, ; Yu, B.; Boerwinkle, E.; Coresh, J.; Chatterjee, N.
10.1101/2021.03.15.435533 — genetics — Posted on 2021-10-06
3456 Cooperative breeding and the emergence of multilevel societies in birds
Camerlenghi, E.; McQueen, A.; Delhey, K.; Cook, C. N.; Kingma, S. A.; Farine, D. R.; Peters, A.
10.1101/2021.10.04.462904 — ecology — Posted on 2021-10-06
3459 RNA-sequencing reveals a gene expression signature in skeletal muscle of a mouse model of age-associated post-operative functional decline
Asche-Godin, S. L.; Graham, Z. A.; Israel, A.; Harlow, L. M.; Huang, W.; Wang, Z.; Brotto, M.; Mobbs, C.; Cardozo, C. P.; Ko, F. C.
10.1101/2021.10.05.461928 — molecular biology — Posted on 2021-10-06
3460 In planta dynamics, transport-biases and endogenous functions of mobile siRNAs in Arabidopsis
Brosnan, C. A.; Devers, E. A.; Sarazin, A.; Lim, P.; Lehesranta, S.; Helariutta, Y.; Voinnet, O.
10.1101/2021.10.06.463290 — plant biology — Posted on 2021-10-06
3463 Robust transcriptional indicators of plant immune cell death revealed by spatio-temporal transcriptome analyses
Salguero-Linares, J.; Serrano, I.; Ruiz-Solani, N.; Salas-Gomez, M.; Jyoti Phukan, U.; Gonzalez, V. M.; Bernardo-Faura, M.; Valls, M.; Rengel, D.; Coll, N. S.
10.1101/2021.10.06.463031 — plant biology — Posted on 2021-10-06
3465 Benchmarking challenging small variants with linked and long reads
Wagner, J.; Olson, N. D.; Harris, L.; McDaniel, J.; Khan, Z.; Farek, J.; Mahmoud, M.; Stankovic, A.; Kovacevic, V.; Wenger, A. M.; Rowell, W. J.; Xiao, C.; Yoo, B.; Miller, N.; Rosenfeld, J. A.; Ni, B.; Zarate, S.; Kirsche, M.; Aganezov, S.; Schatz, M.; Narzisi, G.; Byrska-Bishop, M.; Clarke, W.; Evani, U. S.; Markello, C.; Shafin, K.; Zhou, X.; Sidow, A.; Bansal, V.; Ebert, P.; Marschall, T.; Lansdorp, P.; Hanlon, V.; Mattsson, C.-A.; Martinez Barrio, A.; Fiddes, I. T.; Fungtammasan, A.; Chin, C.-S.; Sedlazeck, F. J.; Carroll, A.; Salit, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2020.07.24.212712 — genomics — Posted on 2021-10-06
3467 Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system
Jablonski, L.; Harczos, T.; Wolf, B.; Hoch, G.; Dieter, A.; Hessler, R.; Ayub, S.; Ruther, P.; Moser, T.
10.1101/2020.05.25.114868 — neuroscience — Posted on 2021-10-06
3469 A reference-quality, fully annotated genome from a Puerto Rican individual
Zimin, A. V.; Shumate, A.; Shinder, I.; Heinz, J.; Puiu, D.; Pertea, M.; Salzberg, S. L.
10.1101/2021.06.10.447952 — genomics — Posted on 2021-10-06
3473 Phylogeography of infectious disease: genetic diversity and connectivity of the Ostreid herpesvirus 1 population in France
Delmotte, J.; Pelletier, C.; Morga, B.; Galinier, R.; Jacquot, M.; Petton, B.; Lamy, J.-B.; Kaltz, O.; Avarre, J.-C.; Montagnani, C.; Escoubas, J.-M.
10.1101/2021.04.30.442107 — microbiology — Posted on 2021-10-06
3483 Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment
Ross, J.; McIver, Z.; Lambert, T.; Piergentili, C.; Gallagher, K. J.; Bird, J. E.; Cruickshank, F. L.; James, P.; Zarazua-Arvizu, E.; Horsfall, L. E.; Waldron, K. J.; Wilson, M. D.; Mackay, C. L.; Basle, A.; Clarke, D. J.; Marles-Wright, J.
10.1101/2021.04.15.439977 — biochemistry — Posted on 2021-10-06
3484 Are narrow-ranging species doomed to extinction? Projected dramatic decline in future climate suitability of two highly threatened species
Dubos, N.; Montfort, F.; Grinand, C.; Nourtier, M.; Deso, G.; Probst, J.-M.; Razafimanahaka, J. H.; Andriantsimanarilafy, R. R.; Rakotondrasoa, E. F.; Razafindraibe, P.; Jenkins, R.; Crottini, A.
10.1101/2021.03.30.437650 — ecology — Posted on 2021-10-06
3486 The In Vivo Source of Type I and Type III IFNs is Pathogen Dependent
Sandoval, M. J.; Tseng, H.-C.; Risman, H. P.; Smirnov, S.; Li, Q.; Lin, J.-D.; Rivera, A.; Durbin, R. K.; Kotenko, S. V.; Durbin, J.
10.1101/2021.10.05.463160 — immunology — Posted on 2021-10-05
3490 PU.1 and MYC transcriptional network defines synergistic drug responses to KIT and LSD1 inhibition in acute myeloid leukemia
Smith, B. M.; VanCampen, J.; Kong, G. L.; Yashar, W.; Tsang, Y. H.; Horton, W.; Coleman, D. J.; Estabrook, J.; Lusardi, T. A.; Mills, G. B.; Druker, B. J.; Maxson, J. E.; Braun, T. P.
10.1101/2021.08.24.456354 — cancer biology — Posted on 2021-10-05
3492 Sequence features of retrotransposons allow for epigenetic variability
Costello, K. R.; Leung, A.; Trac, C.; Lee, M.; Basam, M.; Pospisilik, J. A.; Schones, D.
10.1101/2021.06.01.446659 — genomics — Posted on 2021-10-05
3493 Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
Guo, Y.; Chomiak, A. A.; Hong, Y.; Lowe, C. C.; Chan, W.-C.; Andrade, J.; Pan, H.; Zhou, X.; Berezovski, E.; Monuki, E. S.; Feng, Y.
10.1101/2020.10.22.341784 — neuroscience — Posted on 2021-10-05
3495 Neural circuits for dynamics-based segmentation of time series
Tesileanu, T.; Golkar, S.; Nasiri, S.; Sengupta, A. M.; Chklovskii, D. B.
10.1101/2021.04.23.441218 — neuroscience — Posted on 2021-10-05
3497 Prediction Errors Disrupt Hippocampal Representations and Update Episodic Memories
Sinclair, A. H.; Manalili, G. M.; Brunec, I. K.; Adcock, R. A.; Barense, M. D.
10.1101/2020.09.29.319418 — neuroscience — Posted on 2021-10-05
3498 Evolving the Olfactory System with Machine Learning
Wang, P. Y.; Sun, Y.; Axel, R.; Abbott, L.; Yang, G. R.
10.1101/2021.04.15.439917 — neuroscience — Posted on 2021-10-05
3499 Parallel processing of sensory cue and spatial information in the Dentate Gyrus
Tuncdemir, S. N.; Grosmark, A. D.; Turi, G.; Shank, A.; Bowler, J.; Ordek, G.; Losonczy, A.; Hen, R.; Lacefield, C. O.
10.1101/2020.02.13.947903 — neuroscience — Posted on 2021-10-05
3502 Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics
Wong, D. R.; Conrad, J.; Johnson, N.; Ayers, J. I.; Laeremans, A.; Lee, J. C.; Lee, J.; Prusiner, S. B.; Bandyopadhyay, S.; Butte, A. J.; Paras, N. A.; Keiser, M. J.
10.1101/2021.01.08.425973 — pharmacology and toxicology — Posted on 2021-10-05
3503 Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice
Wang, S.; Lee, K.; Gray, S.; Zhang, Y.; Tangcatherin, C.; Morrish, R.; Tosti, E.; van Oers, J.; Cohen, P.; MacCarthy, T.; Roa, S.; Scharff, M. D.; Edelmann, W.; Chahwan, R.
10.1101/2021.10.05.463200 — cancer biology — Posted on 2021-10-05
3504 Enabling in vivo Analysis Via Nanoparticle-mediated Intracellular Assay Probe Delivery: Using RAS as the Prototype
Chen, F.; Liu, Q.; Hilliard, T.; Wang, T.; Dong, Z.; Li, W.; Liang, H.; Gao, W.; Huang, L.; Wang, D.
10.1101/2020.07.05.188862 — biochemistry — Posted on 2021-10-05
3505 Nde1 is Required for Heterochromatin Compaction and Stability in Neocortical Neurons
Chomiak, A. A.; Lowe, C. C.; Guo, Y.; Mcdaniel, D.; Pan, H.; Zhou, X.; Zhou, Q.; Doughty, M. L.; Feng, Y.
10.1101/2021.06.25.449848 — genetics — Posted on 2021-10-05
3506 Hierarchy-guided Neural Networks for Species Classification
Elhamod, M.; Diamond, K. M.; Maga, A. M.; Bakis, Y.; Bart, H. L.; Mabee, P.; Dahdul, W.; Leipzig, J.; Greenberg, J.; Avants, B.; Karpatne, A.
10.1101/2021.01.17.427006 — evolutionary biology — Posted on 2021-10-05
3508 Differential use of multiple genetic sex determination systems in divergent ecomorphs of an African crater lake cichlid
Munby, H.; Linderoth, T.; Fischer, B.; Du, M.; Vernaz, G.; Tyers, A. M.; Ngatunga, B. P.; Shechonge, A.; Denise, H.; McCarthy, S. A.; Bista, I.; Miska, E. A.; Santos, M. E.; Genner, M. J.; Turner, G. F.; Durbin, R.
10.1101/2021.08.05.455235 — evolutionary biology — Posted on 2021-10-05
3509 Computational capability of ecological dynamics
Ushio, M.; Watanabe, K.; Fukuda, Y.; Tokudome, Y.; Nakajima, K.
10.1101/2021.09.15.460556 — ecology — Posted on 2021-10-05
3510 A mechanochemical model recapitulates distinct vertebrate gastrulation modes
Serra, M.; Najera, G. S.; Chuai, M.; Spandan, V.; Weijer, C. J.; Mahadevan, L.
10.1101/2021.10.03.462928 — developmental biology — Posted on 2021-10-05
3511 Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate.
Parichha, A.; Suresh, V.; Chatterjee, M.; Khsirsagar, A.; Ben-Reuven, L.; Olender, T.; Taketo, M. M.; Holtzman, M. J.; Radosevic, V.; Bobic-Rasonja, M.; Trinski, S.; Jovanov Milosevic, N.; Reiner, O.; Tole, S.
10.1101/2020.12.08.415588 — developmental biology — Posted on 2021-10-05
3513 On the topochronic map of the human brain dynamics
Sorrentino, P.; Petkoski, S.; Sparaco, M.; Troisi Lopez, E.; Signoriello, E.; Baselice, F.; Bonavita, S.; Pirozzi, M. A.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.
10.1101/2021.07.01.447872 — neuroscience — Posted on 2021-10-05
3514 Sponging of glutamate at the outer plasma membrane surface reveals roles for glutamate in development
Castro-Rodriguez, V.; Kleist, T. J.; Gappel, N. M.; Atanjaoui, F.; Okumoto, S.; Machado, M.; Denyer, T.; Timmermans, M. C. P.; Frommer, W. B.; Wudick, M. M.
10.1101/2020.03.24.005223 — plant biology — Posted on 2021-10-05
3516 Frisky CALF sometimes outruns LASSO
Jeffries, C. D.; Ford, J. R.; Tilson, J. L.; Perkins, D. O.; Bost, D.; Filer, D.; Wilhelmsen, K. C.
10.1101/2020.03.27.011700 — bioinformatics — Posted on 2021-10-05
3518 Nuclear genome of a pedinophyte pinpoints genomic innovation and streamlining in the green algae
Repetti, S. I.; Iha, C.; Uthanumallian, K.; Jackson, C. J.; Chen, Y.; Chan, C. X.; Verbruggen, H.
10.1101/2021.10.04.463119 — evolutionary biology — Posted on 2021-10-05
3521 GRASP55 regulates mutant huntingtin unconventional secretion and aggregation
Ahat, E.; Bui, S.; Zhang, J.; da Veiga Leprevost, F.; Sharkey, L. M.; Reid, W.; Nesvizhskii, A. I.; Paulson, H. L.; Wang, Y.
10.1101/2021.10.05.463252 — cell biology — Posted on 2021-10-05
3522 Building regulatory landscapes: enhancer recruits cohesin to create contact domains, engage CTCF sites and activate distant genes
Rinzema, N. J.; Sofiadis, K.; Tjalsma, S. J. D.; Verstegen, M. J. A. M.; Oz, Y.; Valdes-Quezada, C.; Felder, A.-K.; Filipovska, T.; van der Elst, S.; de Andrade dos Ramos, Z.; Han, R.; Krijger, P. H. L.; de Laat, W.
10.1101/2021.10.05.463209 — molecular biology — Posted on 2021-10-05
3525 Identification of a novel cationic glycolipid in Streptococcus agalactiae that contributes to brain entry and meningitis
Joyce, L. R.; Manzer, H. S.; da C. Mendonca, J.; Villarreal, R.; Nagao, P. E.; Doran, K. S.; Palmer, K. L.; Guan, Z.
10.1101/2020.12.01.406702 — microbiology — Posted on 2021-10-05
3526 Chromatin binding of survivin regulates glucose metabolism in the IFN-g producing CD4+T cells
Erlandsson, M. C.; Andersson, K. M.; Oparina, N. Y.; Chandrasekaran, V.; Damdimopoulos, A.; Garcia-Bonete, M.-J.; Einbeigi, Z.; Silfversward, S. T.; Pekna, M. C.; Katona, G. C.; Bokarewa, M. I.
10.1101/2021.10.05.463166 — immunology — Posted on 2021-10-05
3527 The Mouse Action Recognition System (MARS) software pipeline for automated analysis of social behaviors in mice
Segalin, C.; Williams, J.; Karigo, T.; Hui, M.; Zelikowsky, M.; Sun, J. J.; Perona, P.; Anderson, D. J.; Kennedy, A.
10.1101/2020.07.26.222299 — neuroscience — Posted on 2021-10-05
3529 An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus
Navickas, A.; Asgharian, H.; Winkler, J.; Fish, L.; Garcia, K.; Markett, D.; Dodel, M.; Culbertson, B.; Miglani, S.; Joshi, T.; Nguyen, P.; Zhang, S.; Stevers, N.; Hwang, H.-W.; Mardakheh, F.; Goga, A.; Goodarzi, H.
10.1101/2021.10.04.463118 — cancer biology — Posted on 2021-10-05
3532 Performance Comparison of Computational Prediction Methods for the Function and Pathogenicity of Non-coding Variants
Wang, Z.; Zhao, G.; Li, B.; Fang, Z.; Chen, Q.; Wang, X.; Luo, T.; Wang, Y.; Zhou, Q.; Li, K.; Xia, L.; Zhang, Y.; Zhou, X.; Pan, H.; Zhao, Y.; Wang, Y.; Wang, L.; Guo, J.; Tang, B.; Xia, K.; Li, J.
10.1101/2021.10.05.463137 — bioinformatics — Posted on 2021-10-05
3533 Ubr1-induced selective endo-phagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress
Wang, B. B.; Xu, H.; Isenmann, S.; Huang, C.; Elorza-Vidal, X.; Rychkov, G.; Estevez, R.; Schittenhelm, R. B.; Lukacs, G.; Apaja, P. M.
10.1101/2021.10.05.463117 — biochemistry — Posted on 2021-10-05
3536 Towards CRISPR/Cas9-based gene drive in the diamondback moth Plutella xylostella
Xu, X.; Harvey-Samuel, T.; Siddiqui, H. A.; Ang, J.; Anderson, M. E.; Reitmayer, C.; Lovett, E.; Leftwich, P. T.; You, M.; Alphey, L.
10.1101/2021.10.05.462963 — genetics — Posted on 2021-10-05
3538 Sequencing of Argonaute-bound miRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a
Fields, C. J.; Li, L.; Hiers, N. M.; Li, T.; Sheng, P.; Huda, T.; Shan, J.; Gay, L.; Bian, J.; Kilberg, M. S.; Renne, R.; Xie, M.
10.1101/2021.10.05.463240 — molecular biology — Posted on 2021-10-05
3539 TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Upadhyay, A. A.; Hoang, T. N.; Pino, M.; Boddapati, A. K.; Viox, E. G.; Lee, M. Y. H.; Corry, J.; Strongin, Z.; Cowan, D. A.; Beagle, E. N.; Horton, T. R.; Hamilton, S.; Aoued, H.; Harper, J. L.; Nguyen, K.; Pellegrini, K. L.; Tharp, G. K.; Piantadosi, A.; Levit, R. D.; Amara, R. R.; Barratt-Boyes, S. M.; Ribeiro, S. P.; Sekaly, R. P.; Vanderford, T. H.; Schinazi, R. F.; Paiardini, M.; Bosinger, S. E.
10.1101/2021.10.05.463212 — microbiology — Posted on 2021-10-05
3540 A high-carbohydrate diet prolongs dysbiosis and Clostridioides difficile carriage and increases late-onset CDI and mortality in a hamster model of infection
Bhute, S.; Mefferd, C. C.; Phan, J. R.; Ahmed, M.; Fox-King, A. E.; Alarcia, S.; Villarama, J. V.; Abel-Santos, E.; Hedlund, B. P.
10.1101/2021.10.04.463142 — microbiology — Posted on 2021-10-05
3542 Chlorhexidine reduced susceptibility associated to tetracycline resistance in clinical isolates of Escherichia coli
ROYER, G.; Ortiz de la Rosa, J.-M.; Vuillemin, X.; Lacombe, B.; Chau, F.; Clermont, O.; Mercier-Darty, M.; Decousser, J.-W.; Ricard, J.-D.; Nordmann, P.; Denamur, E.; Poirel, L.
10.1101/2021.10.05.463149 — microbiology — Posted on 2021-10-05
3544 Engineered natural killer cells impede the immunometabolic CD73-adenosine axis in solid tumors
Chambers, A. M.; Lupo, K. B.; Wang, J.; Cao, J.; Toregrosa-Allen, S.; Elzey, B.; Pine, S.; Jalal, S.; Utturkar, S.; Atallah Lanman, N.; Bernal-Crespo, V.; Matosevic, S.
10.1101/2021.10.05.463201 — immunology — Posted on 2021-10-05
3547 The maize gene maternal depression of r1 (mdr1) encodes a DNA glycosylase with maternal and paternal fertility functions
Gent, J. I.; Swentowsky, K. W.; Higgins, K. M.; Fu, F.-F.; Zeng, Y.; Kim, D. W.; Dawe, R. K.; Springer, N. M.; Anderson, S. N.
10.1101/2021.10.04.463062 — genetics — Posted on 2021-10-05
3548 HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming
Lu, X.; Fong, K. W.; Gritsina, G.; Wang, F.; Baca, S. C.; Berchuck, J.; Ross, J.; Corey, E.; Catalona, W.; Chandel, N. S.; Yang, X.; Freedman, M. L.; Zhao, J. C.; Yu, J.
10.1101/2021.10.04.463081 — cancer biology — Posted on 2021-10-05
3549 Induced antigen-binding polyspecificity in human serum IgA
Gorshkova, E. N.; Lecerf, M.; Astrakhantseva, I. V.; Vasilenko, E. A.; Starkina, O. V.; Ilyukina, N. A.; Dimitrova, P. A.; Dimitrov, J. D.; Vassilev, T. L.
10.1101/2021.09.29.461938 — immunology — Posted on 2021-10-05
3553 SFI1 and centrin form a distal end complex critical for proper centriole architecture and ciliogenesis
Bouhlel, I.; Laporte, M.; Bertiaux, E.; Giroud, A.; Borgers, S.; Azimzadeh, J.; Borneans, M.; Guichard, P.; Paoletti, A.; Hamel, v.
10.1101/2021.10.05.463184 — cell biology — Posted on 2021-10-05
3555 LGG-1/GABARAP lipidation is dispensable for autophagy and development in C .elegans
Leboutet, R.; Largeau, C.; Prigent, M.; Quinet, G.; Rodriguez, M. S.; Cuif, M.-H.; Culetto, E.; Lefebvre, C.; Legouis, R.
10.1101/2021.10.05.462725 — cell biology — Posted on 2021-10-05
3558 Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients
LaSalle, T. J.; Gonye, A. L. K.; Freeman, S. S.; Kaplonek, P.; Gushterova, I.; Kays, K. R.; Manakongtreecheep, K.; Tantivit, J.; Rojas-Lopez, M.; Russo, B. C.; Sharma, N.; Thomas, M. F.; Lavin-Parsons, K. M.; Lilly, B. M.; Mckaig, B. N.; Charland, N. C.; Khanna, H. K.; Lodenstein, C. L.; Margolin, J. D.; Blaum, E. M.; Lirofonis, P. B.; Sonny, A.; Bhattacharyya, R. P.; Parry, B. A.; Goldberg, M. B.; Alter, G.; Filbin, M. R.; Villani, A. C.; Hacohen, N.; Sade-Feldman, M.
10.1101/2021.10.04.463121 — immunology — Posted on 2021-10-05
3559 A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry
Xu, M.; Pradhan, M.; Gorshkov, K.; Petersen, J. D.; Shen, M.; Guo, H.; Zhu, W.; Klumpp-Thomas, C.; Michael, S.; Itkin, M.; Itkin, Z.; Straus, M. R.; Zimmerberg, J.; Zheng, W.; Whittaker, G.; Chen, C. Z.
10.1101/2021.10.04.463106 — pharmacology and toxicology — Posted on 2021-10-05
3560 Lung-selective Cas13d-based nanotherapy inhibits lethal SARS-CoV-2 infection by targeting host protease Ctsl
Cui, Z.; Zeng, C.; Huang, F.; Yuan, F.; Yan, J.; Zhao, Y.; Huang, J.; Staats, H. F.; Everitt, J. I.; Sempowski, G. D.; Wang, H.; Dong, Y.; Liu, S.-L.; Wang, Q.
10.1101/2021.10.03.462915 — microbiology — Posted on 2021-10-05
3561 Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model
Langel, S. N.; Johnson, S.; Martinez, C. I.; Tedjakusuma, S. N.; Peinovich, N.; Dora, E. G.; Kuehl, P. J.; Irshad, H.; Barrett, E. G.; Werts, A.; Tucker, S. N.
10.1101/2021.10.03.462919 — immunology — Posted on 2021-10-05
3562 Proteoglycan Clusters as a Site of Coordinated, Multi-Dendritic Plasticity
Chelini, G.; Durning, P. T.; O'Donovan, S. M.; Klengel, T.; Balasco, L.; Berciu, C.; Boyer-Boiteau, A.; Bozzi, Y.; McCullumsmith, R.; Ressler, K. J.; Berretta, S.
10.1101/2021.10.04.462691 — neuroscience — Posted on 2021-10-05
3563 Video-evoked fMRI BOLD responses are highly consistent across different data acquisition sites
Byrge, L.; Kliemann, D.; He, Y.; Cheng, H.; Tyszka, J. M.; Adolphs, R.; Kennedy, D. P.
10.1101/2021.10.04.463088 — neuroscience — Posted on 2021-10-05
3567 Proteasome-associated ubiquitin ligase relays target plant hormone-specific transcriptional activators
Wang, Z.; Orosa-Puente, B.; Nomoto, M.; Grey, H.; Potuschak, T.; Matsuura, T.; Mori, I. C.; Tada, Y.; Genschik, P.; Spoel, S. H.
10.1101/2021.10.04.462757 — plant biology — Posted on 2021-10-05
3568 Chromatin changes in PIF-regulated genes parallel their rapid transcriptional response to light
Gonzalez-Grandio, E.; Alamos, S.; Zhang, Y.; Dalton-Roesler, J.; Niyogi, K. K.; Garcia, H. G.; Quail, P. H.
10.1101/2021.10.04.463089 — plant biology — Posted on 2021-10-05
3569 Regressive evolution of an effector following a host jump in the Irish Potato Famine Pathogen Lineage
Zess, E. K.; Dagdas, Y. F.; Peers, E.; Maqbool, A.; Banfield, M. J.; Bozkurt, T. O.; Kamoun, S.
10.1101/2021.10.04.463104 — plant biology — Posted on 2021-10-05
3570 Automatic Metadata Generation for Fish Specimen Image Collections
Pepper, J.; Greenberg, J.; Bakis, Y.; Wang, X.; Bart, H. L.; Breen, D. E.
10.1101/2021.10.04.463070 — bioinformatics — Posted on 2021-10-05
3573 Synergy of turbulence and fishing reduce aquatic biomass
McKerral, J. C.; Seymour, J. R.; Lavery, T. J.; Rogers, P. J.; Jeffries, T. C.; Paterson, J. S.; Roudnew, B.; Huveneers, C.; Newton, K.; van Dongen-Vogels, V.; Cribb, N. P.; Winn, K. M.; Smith, R. J.; Beckmann, C. L.; Prime, E.; Charlton, C. M.; Kleshnina, M.; Grigson, S. R.; Takeuchi, M.; Seuront, L.; Mitchell, J. G.
10.1101/2021.10.04.459351 — ecology — Posted on 2021-10-05
3574 Event-driven acquisition for content-enriched microscopy
Mahecic, D.; Stepp, W. L.; Zhang, C.; Griffie, J.; Weigert, M.; Manley, S.
10.1101/2021.10.04.463102 — cell biology — Posted on 2021-10-05
3575 Development and Validation of a MALDI-TOF-Based Model to Predict Extended-Spectrum Beta-Lactamase and/or Carbapenemase-Producing in Klebsiella pneumoniae Clinical Isolates
Guerrero-Lopez, A.; Candela, A.; Sevilla-Salcedo, C.; Hernandez-Garcia, M.; Martinez-Olmos, P.; Canton, R.; Munoz, P.; del Campo, R.; Gomez-Verdejo, V.; Rodriguez-Sanchez, B.
10.1101/2021.10.04.463058 — microbiology — Posted on 2021-10-05
3576 Brain networks in human conscious visual perception
Kronemer, S. I.; Aksen, M.; Ding, J.; Ryu, J. H.; Xin, Q.; Ding, Z.; Prince, J. S.; Kwon, H.; Khalaf, A.; Forman, S.; Jin, D.; Wang, K.; Chen, K.; Hu, C.; Agarwal, A.; Saberski, E.; Wafa, S. M. A.; Morgan, O. P.; Wu, J.; Christison-Lagay, K. L.; Hasulak, N.; Morrell, M.; Urban, A.; Constable, R. T.; Pitts, M.; Richardson, R. M.; Crowley, M. J.; Blumenfeld, H.
10.1101/2021.10.04.462661 — neuroscience — Posted on 2021-10-05
3583 Prefrontal neural ensembles encode an internal model of visual sequences and their violations
Bellet, M. E.; Gay, M.; Bellet, J.; Jarraya, B.; Dehaene, S.; van Kerkoerle, T.; Panagiotaropoulos, T. I.
10.1101/2021.10.04.463064 — neuroscience — Posted on 2021-10-05
3585 A mitochondrial electron transport chain with atypical subunit composition confers oxygen sensitivity to a mammalian chemoreceptor
Timon-Gomez, A.; Scharr, A. L.; Wong, N. Y.; Ni, E.; Roy, A.; Liu, M.; Chau, J.; Lampert, J. L.; Hireed, H.; Kim, N. S.; Jan, M.; Gupta, A. R.; Day, R. W.; Gardner, J. M.; Wilson, R. J.; Barrientos, A.; Chang, A. J.
10.1101/2021.10.04.463079 — physiology — Posted on 2021-10-05
3587 CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
Höijer, I.; Emmanouilidou, A.; Östlund, R.; van Schendel, R.; Bozorgpana, S.; Feuk, L.; Gyllensten, U.; den Hoed, M.; Ameur, A.
10.1101/2021.10.05.463186 — genomics — Posted on 2021-10-05
3588 A synthesis of senescence predictions for indeterminate growth, and support from multiple tests in wild lake trout
Purchase, C. F.; Rooke, A. C.; Gaudry, M. J.; Treberg, J. R.; Mittell, E. A.; Morrissey, M. B.; Rennie, M. D.
10.1101/2021.10.05.463025 — evolutionary biology — Posted on 2021-10-05
3595 Boundary domain genes were recruited to suppress bract growth and promote branching in maize
Xiao, Y.; Guo, J.; Dong, Z.; Richardson, A.; Patterson, E.; Mangrum, S.; Bybee, S.; Bertolini, E.; Bartlett, M.; Chuck, G.; Eveland, A. L.; Scanlon, M. J.; Whipple, C.
10.1101/2021.10.05.463134 — plant biology — Posted on 2021-10-05
3597 Modular, synthetic chromosomes as new tools for large scale engineering of metabolism
Postma, E.; Hassing, E.-J.; Mangkusaputra, V.; Geelhoed, J.; de la Torre, P.; van den Broek, M.; Mooiman, C.; Pabst, M.; Daran, J.-M.; Daran-Lapujade, P.
10.1101/2021.10.04.462994 — bioengineering — Posted on 2021-10-05
3598 All-trans retinoic acid induces GADD34 gene expression via transcriptional regulation by Six1-TLE3 and post-transcriptional regulation by p38-TTP in skeletal muscle
Adachi, Y.; Masuda, M.; Sakakibara, I.; Uchida, T.; Niida, Y.; Mori, Y.; Kamei, Y.; Okumura, Y.; Ohminami, H.; Ohnishi, K.; Yamanaka-Okumura, H.; Nikawa, T.; Taketani, Y.
10.1101/2021.10.04.463012 — biochemistry — Posted on 2021-10-05
3606 Structure of an ant-myrmecophile-microbe community
Perry, E. K.; Siozios, S.; Hurst, G. D. D.; Parker, J.
10.1101/2021.10.04.462948 — ecology — Posted on 2021-10-05
3607 Coordination between metabolic transitions and gene expression by NAD+ availability during adipogenic differentiation in human cells.
Sanchez Ramirez, E.; Ung, T. P. L.; del Toro Rios, X.; Fajardo Orduna, G. R.; Noriega, L. G.; Tovar, A. R.; Montesinos, J. J.; Orozco Solis, R.; Stringari, C.; Aguilar Arnal, L.
10.1101/2021.10.04.462470 — cell biology — Posted on 2021-10-05
3608 Ancient and modern geochemical signatures in the 13,500-year sedimentary record of Lake Cadagno
Berg, J. S.; Lepine, M.; Laymand, E.; Han, X.; Bernasconi, S.; Su, G.; Vogel, H.; Morlock, M. A.; Gajendra, N.; Gilli, A.; Schubert, C. J.; Lever, M. A.
10.1101/2021.10.04.463023 — microbiology — Posted on 2021-10-05
3609 T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin
Lindqvist, B.; Assi, W.; Roux, J.; Love, L.; Jütte, B. B.; Sönnerborg, A.; Verdin, E.; Svensson, J. P.
10.1101/2021.10.04.461021 — microbiology — Posted on 2021-10-05
3611 Integrative analysis of scRNAs-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
Akiyama, T.; MIyao, T.; Miyauchi, M.; Kelly, T.; Terooatea, T. W.; Ishikawa, T.; Oh, E.; Hirai, S.; Horie, K.; Takakura, Y.; Ohki, H.; Hayama, M.; Maruyama, Y.; Seki, T.; Yabukami, H.; Yoshida, M.; Inoue, A.; Sakaue-Sawano, A.; Miyawaki, A.; Minoda, A.; Akiyama, N.
10.1101/2021.10.04.463004 — immunology — Posted on 2021-10-05
3612 Spatial and temporal analysis of neutrophil trans-epithelial migration in response to RSV infection
Robinson, E.; Herbert, J. A.; Palor, M.; Ren, L.; Larken, I.; Patel, A.; Moulding, D.; Cortina-Borja, M.; Smyth, R.; Smith, C. M.
10.1101/2021.10.04.463016 — immunology — Posted on 2021-10-05
3614 Ptbp1 deletion does not induce glia-to-neuron conversion in adult mouse retina and brain.
Blackshaw, S.; Hoang, T.; Kim, D. W.; Appel, H.; Pannullo, N.; Ozawa, M.; Zheng, S.; Yu, M.; Peachey, N.; Kim, J.
10.1101/2021.10.04.462784 — neuroscience — Posted on 2021-10-05
3615 Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein
Brzozowski, C. F.; Hijaz, B. A.; Singh, V.; Gcwensa, N. Z.; Kelly, K.; Boyden, E. S.; West, A.; Sarkar, D.; Volpicelli-Daley, L. A.
10.1101/2021.10.04.463043 — neuroscience — Posted on 2021-10-05
3617 Early diagnosis of Parkinson's disease: A cross-species biomarker
Mallet, D.; Dufourd, T.; Decourt, M.; Carcenac, C.; Bossu, P.; Verlin, L.; Fernagut, P. O.; Benoit-Marand, M.; Spalletta, G.; Barbier, E.; Carnicella, S.; Sgambato, V.; Fauvelle, F.; Boulet, S.
10.1101/2021.10.04.462993 — pathology — Posted on 2021-10-05
3618 Models of the cardiac L-type calcium current: a quantitative comparison
Agrawal, A.; Wang, K.; Polonchuk, L.; Cooper, J.; Mirams, G. R.; Gavaghan, D. J.; Clerx, M.
10.1101/2021.10.04.462988 — cell biology — Posted on 2021-10-05
3619 Almost nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, as an olfactory chemoattractant for the grass puffer
Noguchi, Y.; Suzuki, T.; Matsutani, K.; Sakakibara, R.; Nakahigashi, R.; Adachi, M.; Nishikawa, T.; Abe, H.
10.1101/2021.09.12.459881 — zoology — Posted on 2021-10-05
3625 β-amyloid-driven synaptic depression requires PDZ protein interaction at AMPA-receptor subunit GluA3
Reinders, N.; van der Spek, S.; Klaassen, R. V.; Koymans, K.; Li, K. W.; Smit, A.; Kessels, H.
10.1101/2021.10.03.462970 — neuroscience — Posted on 2021-10-05
3627 Postsynaptic synucleins mediate vesicular exocytosis of endocannabinoids
Albarran, E.; Sun, Y.; Liu, Y.; Raju, K.; Dong, A.; Li, Y.; Wang, S.; Sudhof, T. C.; Ding, J. B.
10.1101/2021.10.04.462870 — neuroscience — Posted on 2021-10-05
3630 Circadian regulation of the transcriptome in a complex polyploid crop
Rees, H.; Rusholme-Pilcher, R.; Bailey, P.; Colmer, J.; White, B.; Reynolds, C.; Graham, C. A.; Dantas, L. L. d. B.; Dodd, A. N.; Hall, A.
10.1101/2021.09.30.462369 — plant biology — Posted on 2021-10-05
3633 Stochastic variational variable selection for high-dimensional microbiome data
Dang, T.; Kumaishi, K.; Usui, E.; Kobori, S.; Sato, T.; Ichihashi, Y.; Yusuke, T.; Yamasaki, Y.; Tsujimoto, H.; Iwata, H.
10.1101/2021.10.04.462986 — bioinformatics — Posted on 2021-10-05
3637 Robust T cell activation requires an eIF3-driven burst in T cell receptor translation
DeSilva, D.; Ferguson, L.; Chin, G.; Smith, B.; Apathy, R.; Roth, T.; Blaeschke, F.; Kudla, M.; Marson, A.; Ingolia, N. T.; Cate, J. H.
10.1101/2021.10.04.463005 — molecular biology — Posted on 2021-10-05
3639 3D Convolutional Neural Networks for Classification of Alzheimer's and Parkinson's Disease with T1-Weighted Brain MRI
Dhinagar, N. J.; Thomopoulos, S. I.; Owens-Walton, C.; Stripelis, D.; Ambite, J.-L.; Ver Steeg, G.; Weintraub, D.; Cook, P.; McMillan, C.; Thompson, P. M.
10.1101/2021.07.26.453903 — bioinformatics — Posted on 2021-10-05
3640 A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially resolved tissue phenotypingat single-cell resolution.
Bortolomeazzi, M.; Montorsi, L.; Temelkovski, D.; Keddar, M. R.; Acha-Sagredo, A.; Pitcher, M. J.; Basso, G.; Laghi, L.; Rodriguez-Justo, M.; Spencer, J.; Ciccarelli, F. D.
10.1101/2021.04.01.437886 — bioinformatics — Posted on 2021-10-05
3641 A sensitized genetic screen to identify regulators of C. elegans germline stem cells
Robinson-Thiewes, S.; Kershner, A. M.; Shin, H.; Haupt, K. A.; Kroll-Conner, P.; Kimble, J.
10.1101/2021.10.03.462952 — genetics — Posted on 2021-10-05
3642 Dysfunction of an energy sensor NFE2L1 triggers uncontrollable AMPK signal and glucose metabolism reprogramming
Yang, Q.; Zhao, W.; Xing, Y.; Li, P.; Zhou, X.; Ning, H.; Shi, R.; Gou, S.; Chen, Y.; Zhai, W.; Wu, Y.; Li, G.; Chen, Z.; Ren, Y.; Gao, Y.; Zhang, Y.; Qi, Y.; Qiu, L.
10.1101/2021.09.07.459348 — molecular biology — Posted on 2021-10-05
3643 AIM2 inflammasome activation in astrocytes occurs during the late phase of EAE
Barclay, W. E.; Deerhake, M. E.; Inoue, M.; Nonaka, T.; Nozaki, K.; Luzum, N. A.; Aggarwal, N.; Miao, E. A.; Shinohara, M. L.
10.1101/2021.10.03.462457 — immunology — Posted on 2021-10-05
3648 Effect of cow's milk with different PUFA n-6: n-3 ratios on performance, serum lipid profile, and blood parameters of grower gilts.
Netto, A. S.; Reis, L. G.; Silva, T. H. d.; Salles, M. S.; Andrade, A. F.; Martins, S. M.; Takeuchi, P. L.; Vidal, A. M. C.
10.1101/2021.10.04.463091 — physiology — Posted on 2021-10-04
3650 Population ecology of seabirds in Mexican Islands at the California Current System
Mendez Sanchez, F.; Bedolla Guzman, Y.; Rojas Mayoral, E.; Aguirre-Munoz, A.; Koleff, P.; Aguilar Vargas, A.; Alvarez Santana, F.; Arnaud, G.; Aztorga Ornelas, A.; Beltran Morales, L. F.; Bello Yanez, M.; Berlanga Garcia, H.; Bravo Hernandez, E.; Cardenas Tapia, A.; Castellanos Vera, A.; Corrales Sauceda, M.; Duarte Canizales, A.; Fabila Blanco, A.; Felix Lizarraga, M.; Fernandez Robledo, A.; Hernandez Montoya, J.; Hernandez Rios, A.; Inigo-Elias, E.; Mendez Rosas, A.; Rojas Mayoral, B.; Solis Carlos, F.; Ortega Rubio, A.
10.1101/2021.10.04.463095 — ecology — Posted on 2021-10-04
3652 recount3: summaries and queries for large-scale RNA-seq expression and splicing
Wilks, C.; Zheng, S. C.; Chen, F. Y.; Charles, R.; Solomon, B.; Ling, J. P.; Imada, E. L.; Zhang, D.; Joseph, L.; Leek, J. T.; Jaffe, A. E.; Nellore, A.; Collado-Torres, L.; Hansen, K. D.; Langmead, B.
10.1101/2021.05.21.445138 — genomics — Posted on 2021-10-04
3657 Predicting compound activity from phenotypic profiles and chemical structures
Caicedo, J. C.; Moshkov, N.; Becker, T.; Yang, K.; Horvath, P.; Dancik, V. C.; Wagner, B. K.; Clemons, P. C.; Singh, S.; Carpenter, A. E.
10.1101/2020.12.15.422887 — bioinformatics — Posted on 2021-10-04
3659 De Novo Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome, an Animal Model for Severe/Critical COVID-19
Andreotti, S.; Altmüller, J.; Quedenau, C.; Borodina, T.; Nouailles, G.; Teixeira Alves, L. G.; Landthaler, M.; Bieniara, M.; Trimpert, J.; Wyler, E.
10.1101/2021.10.02.462569 — genomics — Posted on 2021-10-04
3664 Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry
Hayashi-Takanaka, Y.; Hayashi, Y.; Hirano, Y.; Miyawaki-Kuwakado, A.; Ohkawa, Y.; Obuse, C.; Kimura, H.; Haraguchi, T.; Hiraoka, Y.
10.1101/2021.05.14.443718 — cell biology — Posted on 2021-10-04
3667 Detection of Cell-Cell Interactions via Photocatalytic Cell Tagging
Oslund, R. C.; Reyes-Robles, T.; White, C. H.; Tomlinson, J. H.; Crotty, K. A.; Bowman, E. P.; Chang, D.; Peterson, V. M.; Li, L.; Frutos, S.; Vila-Perello, M.; Vlerick, D.; Cromie, K.; Perlman, D. H.; O'Hara, S. D.; Roberts, L. R.; Piizzi, G.; Hett, E. C.; Hazuda, D. J.; Fadeyi, O. O.
10.1101/2021.10.04.463039 — immunology — Posted on 2021-10-04
3668 Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins
Lublin, A.; Katz, C.; Gruzdev, N.; Yadid, I.; Bloch, I.; Farnoushi, Y.; Simanov, L.; Berkovitz, A.; Elyahu, D.; Pitcovski, J.; Shahar, E.
10.1101/2021.10.04.462992 — immunology — Posted on 2021-10-04
3669 Fluorescence Activation Mechanism and Imaging of Drug Permeation with New Sensors for Smoking-Cessation Ligands
Nichols, A. L.; Blumenfeld, Z.; Fan, C.; Luebbert, L.; Blom, A. E. M.; Cohen, B. N.; Marvin, J. S.; Borden, P. M.; Kim, C.; Muthusamy, A. K.; Shivange, A. V.; Knox, H. J.; Campello, H. R.; Wang, J. H.; Dougherty, D. A.; Looger, L.; Gallagher, T.; Rees, D. C.; Lester, H. A.
10.1101/2021.10.04.463082 — pharmacology and toxicology — Posted on 2021-10-04
3675 Genome-wide association, prediction and heritability in bacteria
Mallawaarachchi, S.; Tonkin-Hill, G.; Croucher, N. J.; Turner, P.; Speed, D.; Corander, J.; Balding, D.
10.1101/2021.10.04.462983 — genomics — Posted on 2021-10-04
3677 Non-coding function for mRNAs in Focal Adhesion Architecture and Mechanotransduction
Boraas, L.; Hu, M.; Thornton, L.; Vejnar, C.; Zhen, G.; Giraldez, A.; Mayr, C.; Wang, S.; Nicoli, S.
10.1101/2021.10.04.463097 — cell biology — Posted on 2021-10-04
3678 Robust T cell activation requires an eIF3-driven burst in T cell receptor translation
DeSilva, D.; Ferguson, L.; Chin, G.; Smith, B.; Apathy, R.; Roth, T.; Blaeschke, F.; Kudla, M.; Marson, A.; Ingolia, N. T.; Cate, J. H.
10.1101/2021.10.04.463005 — molecular biology — Posted on 2021-10-04
3681 Differential timing for glucose assimilation in Prochlorococcus and coexistent microbial populations at the North Pacific Subtropical Gyre
Munoz-Marin, M. d. C.; Duhamel, S.; Bjorkman, K. M.; Magasin, J. D.; Karl, D. M.; Diez, J.; Garcia Fernandez, J. M.
10.1101/2021.10.04.462702 — microbiology — Posted on 2021-10-04
3682 A Mediterranean-like fat blend protects against the development of severe colitis in the mucin-2 deficient murine model
Haskey, N.; Ye, J.; Estaki, M.; Verdugo-Meza, A.; Barnett, J. A.; Yousefi, M.; Birnie, B.; Gruenheid, S.; Ghosh, S.; Gibson, D. L.
10.1101/2021.09.27.462042 — immunology — Posted on 2021-10-04
3683 Gut Microbiome Signatures Linked to HIV-1 Reservoir Size and Viremia Control
Borgognone, A.; Noguera-Julian, M.; Oriol, B.; Noël-Romas, L.; Ruiz-Riol, M.; Guillen, Y.; Parera, M.; Casadella, M.; Duran, C.; Puertas, M. C.; Catala-Moll, F.; De Leon, M.; Knodel, S.; Birse, K.; Manzardo, C.; Miro, J. M.; Clotet, B.; Martinez-Picado, J.; Molto, J.; Mothe, B.; Burgener, A.; Brander, C.; Paredes, R.
10.1101/2021.10.03.462590 — immunology — Posted on 2021-10-04
3684 Nanoengineered DNA origami with repurposed TOP1 inhibitors targeting myeloid cells for the mitigation of neuroinflammation
Zhu, K.; Wang, Y.; Sarlus, H.; Geng, K.; Nutma, E.; Sun, J.; Kang, S.-Y.; Bay, C.; Han, J.; Lund, H.; Amor, S.; Wang, J.; Zhang, X.-m.; Kutter, C.; Ortlieb, A.; Hogberg, B.; Harris, R.
10.1101/2021.10.04.462880 — immunology — Posted on 2021-10-04
3685 Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness
Miyadera, K.; Santana, E.; Roszak, K.; Iffrig, S.; Visel, M.; Iwabe, S.; Boyd, R. F.; Bartoe, J. T.; Sato, Y.; Gray, A.; Ripolles Garcia, A.; Dufour, V. L.; Byrne, L. C.; Flannery, J. G.; Beltran, W. A.; Aguirre, G. D.
10.1101/2021.10.04.462588 — neuroscience — Posted on 2021-10-04
3686 Functional interaction between Drosophila olfactory sensory neurons and their support cells
Prelic, S.; Pal Mahadevan, V.; Venkateswaran, V.; Lavista-Llanos, S.; Hansson, B. S.; Wicher, D.
10.1101/2021.10.04.463011 — neuroscience — Posted on 2021-10-04
3690 Discovery of Aminoglycosides as First in Class, Nanomolar Inhibitors of Heptosyltransferase I
Milicaj, J. A.; Hassan, B. A.; Cote, J. M.; Ramirez-Mondragon, C. A.; Jaunbocus, N. A.; Rafalowski, A. A.; Patel, K. R.; Castro, C. D.; Muthyala, R.; Sham, Y. Y.; Taylor, E. A.
10.1101/2021.10.03.462930 — biochemistry — Posted on 2021-10-04
3693 Development of coarse-grained model for a minimal stratum corneum lipid mixture
Shamaprasad, P.; Moore, T. C.; Xia, D.; Iacovella, C. R.; Bunge, A. L.; McCabe, C.
10.1101/2021.10.04.463115 — biochemistry — Posted on 2021-10-04
3694 Increasing triacylglycerol formation and lipid storage by unsaturated lipids protects renal proximal tubules in diabetes
Perez-Marti, A.; Ramakrishnan, S.; Li, J.; Dugourd, A.; Molenaar, M. R.; De La Motte, L. R.; Grand, K.; Mansouri, A.; Parisot, M.; Lienkamp, S. S.; Saez-Rodriguez, J.; Simons, M.
10.1101/2021.09.07.459360 — cell biology — Posted on 2021-10-04
3695 EPH tyrosine kinase receptors regulate epithelial morphogenesis and phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
Banerjee, S. L.; Lavoie, N.; Jacquet, K.; Lessard, F.; Osornio-Hernandez, A. I.; Lavoie, J. N.; Elowe, S.; Lambert, J.-P.; Laprise, P.; Bisson, N.
10.1101/2020.09.06.285270 — molecular biology — Posted on 2021-10-04
3696 REV7/FANCV Binds to CHAMP1 and Promotes Homologous Recombination Repair
Li, F.; Sarangi, P.; Feng, H.; Moreau, L.; Nguyen, H.; Clairmont, C.; D'Andrea, A. D.
10.1101/2021.10.04.463067 — molecular biology — Posted on 2021-10-04
3697 Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells
Grzywa, T. M.; Sosnowska, A.; Rydzynska, Z.; Lazniewski, M.; Plewczynski, D.; Klicka, K.; Malecka-Gieldowska, M.; Rodziewicz-Lurzynska, A.; Ciepiela, O.; Justyniarska, M.; Pomper, P.; Grzybowski, M. M.; Blaszczyk, R.; Wegrzynowicz, M.; Tomaszewska, A.; Basak, G.; Golab, J.; Nowis, D.
10.1101/2021.01.18.427109 — immunology — Posted on 2021-10-04
3698 Epithelial Immunomodulation by Aerosolized Toll-like Receptor Agonists Attenuates Allergic Responsiveness in Mice
Goldblatt, D. L.; Valverde Ha, G.; Wali, S.; Kulkarni, V. V.; Longmire, M. K.; Jaramillo, A. M.; Chittuluru, R. P.; Fouts, A. M.; Martinez-Moczygemba, M.; Lei, J. T.; Huston, D. P.; Tuvim, M. J.; Dickey, B. F.; Evans, S. E.
10.1101/2021.08.05.455337 — immunology — Posted on 2021-10-04
3701 Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging
Peng, S.; Zeng, L.; Haure-mirande, J.-v.; Wang, M.; Huffman, D. M.; Haroutunian, V.; Ehrlich, M. E.; Zhang, B.; Tu, Z.
10.1101/2021.06.01.446628 — neuroscience — Posted on 2021-10-04
3702 Adaptable and Automated Rodent Behavior Maze System
Olson, J. M.; Leppla, C. A.; Bladon, J. H.; Jadhav, S. P.
10.1101/2021.06.05.447225 — neuroscience — Posted on 2021-10-04
3703 Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition
Blume, T.; Deussing, M.; Biechele, G.; Peters, F.; Zott, B.; Schmidt, C.; Franzmeier, N.; Wind, K.; Eckenweber, F.; Sacher, C.; Shi, Y.; Ochs, K.; Kleinberger, G.; Xiang, X.; Focke, C.; Lindner, S.; Gildehaus, F.-J.; Beyer, L.; von Ungern-Sternberg, B.; Bartenstein, P.; Baumann, K.; Adelsberger, H.; Rominger, A.; Cumming, P.; Willem, M.; Dorostkar, M. M.; Herms, J.; Brendel, M.
10.1101/2021.05.30.446348 — neuroscience — Posted on 2021-10-04
3704 Minimal functional alignment of ventromedial prefrontal cortex intracranial EEG signals during naturalistic viewing
Xie, T.; Cheong, J. H.; Manning, J. R.; Brandt, A. M.; Aronson, J. P.; Jobst, B. C.; Bujarski, K. A.; Chang, L. J.
10.1101/2021.05.10.443308 — neuroscience — Posted on 2021-10-04
3706 Regulation of blood-brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide
Hoyles, L.; Pontifex, M. G.; Rodriguez-Ramiro, I.; Anis-Alavi, M. A.; Jelane, K. S.; Snelling, T.; Solito, E.; Fonseca, S.; Carvalho, A. L.; Carding, S. R.; Müller, M.; Glen, R. C.; Vauzour, D.; McArthur, S.
10.1101/2021.01.28.428430 — systems biology — Posted on 2021-10-04
3707 Sugar beet cold-induced PMT5a and STP13 carriers are poised for taproot proton-driven plasma membrane sucrose and glucose import
Reyer, A.; Bazihizina, N.; Scherzer, S.; Jaslan, J.; Schäfer, N.; Jaslan, D.; Cuin, T. A.; Al-Rasheid, K. A. S.; Alfarhan, A. H.; Alquraishy, S. A.; Ludewig, F.; Koch, W.; Harms, K.; Becker, D.; Müller, T. D.; Pommerrenig, B.; Neuhaus, H. E.; Marten, I.; Hedrich, R.
10.1101/2021.09.21.461191 — plant biology — Posted on 2021-10-04
3709 Expanding the Galaxy's reference data
VijayKrishna, N.; Joshi, J.; Coraor, N.; Hillman-Jackson, J.; Bouvier, D.; van den Beek, M.; Eguinoa, I.; Coppens, F.; Golitsynskiy, S.; Stolarczyk, M.; Sheffield, N. C.; Gladman, S.; Cuccuru, G.; Grüning, B.; Soranzo, N.; Rasche, H.; Langhorst, B. W.; Bernt, M.; Fornika, D.; de Lima Morais, D. A.; Barrette, M.; van Heusden, P.; Petrillo, M.; Puertas-Gallardo, A.; Patak, A.; Hotz, H.-R.; Blankenberg, D.
10.1101/2020.10.09.327114 — bioinformatics — Posted on 2021-10-04
3712 Chromosome size affects sequence divergence between species through the interplay of recombination and selection
Tigano, A.; Khan, R.; Omer, A. D.; Weisz, D.; Dudchenko, O.; Multani, A. S.; Pathak, S.; Behringer, R. D.; Aiden, E. L.; Fisher, H.; MacManes, M. D.
10.1101/2021.01.15.426870 — evolutionary biology — Posted on 2021-10-04
3713 A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis
Baur, K.; Abdullah, Y.; Mandl, C.; Hoelzl-Wenig, G.; Shi, Y.; Schmidt-Edelkraut, U.; Khatri, P.; Hagenston, A. M.; Irmler, M.; Beckers, J.; Ciccolini, F.
10.1101/2020.11.20.391102 — cell biology — Posted on 2021-10-04
3714 Role of the Topoisomerase IIα Chromatin Tether domain in Nucleosome Binding & Chromosome Segregation
Sundararajan, S.; Park, H.; Kawano, S.; Johansson, M.; Saito-Fujita, T.; Saitoh, N.; Arnaoutov, A.; Dasso, M.; Clarke, D.; Azuma, Y.
10.1101/2021.10.03.462934 — cell biology — Posted on 2021-10-04
3716 Deconstructing the Cortical Sources of Frequency Following Responses to Speech: A Cross-species Approach
Gnanateja, G. N.; Rupp, K.; Llanos, F.; Remick, M.; Pernia, M.; Sadagopan, S.; Teichert, T.; Abel, T.; Chandrasekaran, B.
10.1101/2021.05.17.444462 — neuroscience — Posted on 2021-10-04
3718 Slow TCA flux implies low ATP production in tumors
Bartman, C. R.; Shen, Y.; Lee, W. D.; TeSlaa, T.; Jankowski, C. S. R.; Wang, L.; Yang, L.; Roichman, A.; Bhatt, V.; Lan, T.; Hu, Z. S.; Xing, X.; Lu, W.; Guo, J. Y.; Rabinowitz, J. D.
10.1101/2021.10.04.463108 — cancer biology — Posted on 2021-10-04
3719 Densified Collagen Tubular Grafts for Human Tissue Replacement and Disease Modelling Applications
Justin, A. W.; Burgess, S.; Estevez, S. R.; Stavropoulou-Tatla, A.; Ong, J.; Jacob, A. G.; Saeb-Parsy, K.; Sinha, S.; Markaki, A. E.
10.1101/2021.02.05.429744 — bioengineering — Posted on 2021-10-04
3722 Protein complex prediction with AlphaFold-Multimer
Evans, R.; O'Neill, M.; Pritzel, A.; Antropova, N.; Senior, A. W.; Green, T.; Zidek, A.; Bates, R.; Blackwell, S.; Yim, J.; Ronneberger, O.; Bodenstein, S.; Zielinski, M.; Bridgland, A.; Potapenko, A.; Cowie, A.; Tunyasuvunakool, K.; Jain, R.; Clancy, E.; Kohli, P.; Jumper, J.; Hassabis, D.
10.1101/2021.10.04.463034 — bioinformatics — Posted on 2021-10-04
3723 Dalpiciclib and Pyrotinib Exert Synergistic Antitumor Effects in Triple Positive Breast Cancer
Bu, J.; Zhang, Y.; Niu, N.; Bi, K.; Sun, L.; Qiao, X.; Wang, Y.; Zhang, Y.; Jiang, X.; Wang, D.; Ma, Q.; Li, H.; Liu, C.
10.1101/2021.10.04.463019 — cell biology — Posted on 2021-10-04
3725 Structure selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern
Almanza, G.; Kouznetsova, V.; Clark, A. E.; Olmedillas, E.; Castro, A.; Tsigelny, I. F.; Wu, Y.; Gao, G. F.; Ollmann Saphire, E.; Carlin, A. F.; Zanetti, M.
10.1101/2021.10.01.462840 — immunology — Posted on 2021-10-04
3726 TREM2-H157Y Increases Soluble TREM2 Production and Reduces Amyloid Pathology
Qiao, W.; Chen, Y.; Martens, Y.; Liu, C.-c.; Knight, J.; Li, F.; Chen, K.; Kurti, A.; Shue, F.; Dacquel, M. V.; Fryer, J. D.; Zhao, N.; Bu, G.
10.1101/2021.10.04.463020 — neuroscience — Posted on 2021-10-04
3731 Extracellular release of mitochondrial DNA is triggered by cigarette smoke and is detected in COPD
Giordano, L.; Gregory, A. D.; Perez Verdaquer, M.; Ware, S. A.; Harvey, H.; DeVallance, E.; Brzoska, T.; Sundd, P.; Zhang, Y.; Sciurba, F. C.; Shapiro, S. D.; Kaufman, B. A.
10.1101/2021.10.04.462069 — cell biology — Posted on 2021-10-04
3732 Extensive genetic mixing within the clam genus Corbicula
Vastrade, M.; Etoundi, E.; Bournonville, T.; Colinet, M.; Debortoli, N.; Hedtke, S. M.; Nicolas, E.; Pigneur, L.-M.; Virgo, J.; Flot, J.-F.; Marescaux, J.; Van Doninck, K.
10.1101/590836 — evolutionary biology — Posted on 2021-10-04
3733 Allometric scaling of RNA abundance from genes to communities
Lopez, M. L. D.; Lin, Y.-y.; Schneider, S. Q.; Machida, R. J.
10.1101/2021.10.03.462954 — ecology — Posted on 2021-10-04
3734 PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, andRNA polymerase pause release at select gene targets
Zhang, S.; Wang, J.; Liu, Q.; McDonald, W. H.; Bomber, M.; Layden, H.; Ellis, J.; Borinstein, S.; Hiebert, S. W.; Stengel, K. R.
10.1101/2021.10.03.462944 — molecular biology — Posted on 2021-10-04
3738 High-speed live cell interferometry for screening bioprinted organoids
Tebon, P. J.; Wang, B.; Markowitz, A. L.; Murray, G.; Nguyen, H. T. L.; Tavanaie, N.; Nguyen, T. L.; Boutros, P. C.; Teitell, M. A.; Soragni, A.
10.1101/2021.10.03.462896 — bioengineering — Posted on 2021-10-04
3741 Lamina cribrosa vessel and collagen beam networks are distinct
Waxman, S.; Brazile, B. L.; Yang, B.; Gogola, A. L.; Lam, P.; Voorhees, A. P.; Rizzo, J. F.; Jakobs, T. C.; Sigal, I. A.
10.1101/2021.10.03.462932 — bioengineering — Posted on 2021-10-04
3742 Discovery of Aminoglycosides as first in class, nanomolar inhibitors of Heptosyltransferase I
Milicaj, J. A.; Hassan, B. A.; Cote, J. M.; Ramirez-Mondragon, C. A.; Jaunbocus, N. A.; Rafalowski, A. A.; Patel, K. R.; Muthyala, R.; Sham, Y. Y.; Taylor, E. A.
10.1101/2021.10.03.462930 — biochemistry — Posted on 2021-10-04
3747 Global distribution of the rooting zone water storage capacity reflects plant adaptation to the environment
Stocker, B. D.; Tumber-Davila, S. J.; Konings, A. G.; Anderson, M. B.; Hain, C.; Jackson, R. B.
10.1101/2021.09.17.460332 — ecology — Posted on 2021-10-04
3748 Stepwise progression of β-selection during T cell development as revealed by histone deacetylation inhibition
Chann, A. S.; Charnley, M.; Newton, L.; Newbold, A.; Humbert, P. O. O.; Johnstone, R. W.; Russell, S.
10.1101/2021.10.03.462949 — developmental biology — Posted on 2021-10-04
3749 Ratio-based sensing of two transcription factors regulates the transit to differentiation
Bernasek, S. M.; Boisclair Lachance, J.-F.; Pelaez, N.; Hur, S. S.; Bakker, R.; Navarro, H. T.; Sanchez-Luege, N.; Amaral, L. A. N.; Bagheri, N.; Rebay, I.; Carthew, R. W.
10.1101/430744 — developmental biology — Posted on 2021-10-04
3750 Epigenome priming dictates transcription response and white matter fate upon perinatal inflammation
Schang, A.-L.; van Steenwinckel, J.; Lipecki, J.; Rich-Griffin, C.; Woolley-Allen, K.; Dyer, N.; Le Charpentier, T.; Schafer, P.; Fleiss, B.; Ott, S.; Saberan-Djoneidi, D.; Mezger, V.; Gressens, P.
10.1101/411702 — developmental biology — Posted on 2021-10-04
3752 Le Petit Prince: A multilingual fMRI corpus using ecological stimuli
Li, J.; Bhattasali, S.; Zhang, S.; Franzluebbers, B.; Luh, W.-M.; Spreng, R. N.; Brennan, J. R.; Yang, Y.; Pallier, C.; Hale, J. T.
10.1101/2021.10.02.462875 — neuroscience — Posted on 2021-10-04
3754 Microglia mediate synaptic plasticity induced by 10 Hz repetitive magnetic stimulation
Eichler, A.; Kleidonas, D.; Turi, Z.; Kirsch, M.; Pfeifer, D.; Masuda, T.; Prinz, M.; Lenz, M.; Vlachos, A.
10.1101/2021.10.03.462905 — neuroscience — Posted on 2021-10-04
3763 Optimization of anastomotic technique and gastric conduit perfusion with hyperspectral imaging in an experimental model for minimally invasive esophagectomy
Nickel, F.; Studier-Fischer, A.; Oezdemir, B.; Odenthal, J.; Mueller, L.-R.; Knoedler, S.; Kowalewski, K.-F.; Camplisson, I.; Allers, M. M.; Dietrich, M.; Schmidt, K.; Salg, G. A.; Kenngott, H. G.; Billeter, A.; Gockel, I.; Sagiv, C.; Etz-Hadar, O.; Gildenblat, J.; Ayala, L.; Seidlitz, S.; Maier-Hein, L.; Mueller-Stich, B. P.
10.1101/2021.10.03.462901 — bioengineering — Posted on 2021-10-04
3769 Cryo-EM Structure of the Pol Polyprotein Provides Insights into HIV Maturation
Harrison, J. J. E. K.; Passos, D. O.; Bruhn, J. F.; Bauman, J. D.; Tuberty, L.; DeStefano, J. J.; Ruiz, F. X.; Lyumkis, D.; Arnold, E.
10.1101/2021.10.03.462959 — biophysics — Posted on 2021-10-04
3774 The first transchromosomic rat model with human chromosome 21 shows robust Down syndrome features
Kazuki, Y.; Gao, F. J.; Yamakawa, M.; Hirabayashi, M.; Kazuki, K.; Kajitani, N.; Miyagawa-Tomita, S.; Abe, S.; Sanbo, M.; Hara, H.; Kuniishi, H.; Ichisaka, S.; Hata, Y.; Koshima, M.; Takayama, H.; Takehara, S.; Nakayama, Y.; Hiratsuka, M.; Iida, Y.; Matsukura, S.; Noda, N.; Li, Y.; Moyer, A. J.; Cheng, B.; Singh, N.; Richtsmeier, J. T.; Oshimura, M.; Reeves, R. H.
10.1101/2021.10.03.462958 — genetics — Posted on 2021-10-04
3779 Prediction and action in cortical pain processing
Koppel, L.; Novembre, G.; Kämpe, R.; Savallampi, M.; Morrison, I.
10.1101/2021.09.09.459455 — neuroscience — Posted on 2021-10-04
3781 A holobiont view of island biogeography: unraveling patterns driving the nascent diversification of a Hawaiian spider and its microbial associates
Armstrong, E.; Perez-Lamarque, B.; Bi, K.; Chen, C.; Becking, L. E.; Lim, J. Y.; Linderoth, T.; Krehenwinkel, H.; Gillespie, R.
10.1101/2020.12.07.414961 — evolutionary biology — Posted on 2021-10-04
3783 Plant host shift: The viability and persistence of a polyphagous, non-native insect
Bueno Silva, I.; McGrane-Corrigan, B.; Mason, O.; de Andrade Moral, R.; Augusto Conde Godoy, W.
10.1101/2021.09.20.461112 — ecology — Posted on 2021-10-04
3785 Pre-clinical validation of an RNA-based precision oncology platform for patient-therapy alignment in a diverse set of human malignancies resistant to standard treatments
Mundi, P. S.; Dela Cruz, F. S.; Grunn, A.; Diolaiti, D.; Mauguen, A.; Siddiquee, A.; You, D.; Realubit, R.; Karan, C.; Ortiz, M. V.; Accordino, M.; Aloni, Z.; Brogan, F.; Bruce, J.; Caescu, C. I.; Carvajal, R.; Crew, K.; Decastro, G.; Heaney, M.; Henick, B.; Hershman, D.; Hou, J.; Iwamoto, F.; Jurcic, J.; Kiran, P. R.; Kluger, M.; Kreisl, T.; Lamanna, N.; Lassman, A.; Lim, E.; Manji, G.; McKhann, G.; McKiernan, J.; Neugut, A.; Olive, K.; Rosenblat, T.; Schwartz, G. K.; Shu, C.; Sisti, M.; Tergas, A.; Vattakalam, R.; Welch, M.; Wenske, S.; Wright, J.; Hibshoosh, H.; Kalinsky, K.; Aburi, M.; Sim
10.1101/2021.10.03.462951 — systems biology — Posted on 2021-10-03
3786 A Eukaryotic Circuit for Secrete-and-Sense Autonomy
Qiao, L.; Abd El-Hafeez, A. A.; Lo, I.-C.; Sinha, S.; Midde, K.; Ngo, T.; Aznar, N.; Lopez-Sanchez, I.; Gupta, V.; Farquhar, M.; Rangamani, P.; Ghosh, P.
10.1101/2021.03.18.436048 — systems biology — Posted on 2021-10-03
3788 A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down Scaling
Turrigiano, G. G.; Wu, C.-H.; Tatavarty, V.; Jean-Beltran, P. M.; Guerrero, A.; Keshishian, H.; Krug, K.; MacMullan, M. A.; Li, L.; Carr, S. A.; Cottrell, J. R.
10.1101/2021.10.03.462942 — neuroscience — Posted on 2021-10-03
3790 Stress-dependent dynamic and reversible formation of cytoskeleton-like filaments and gel-transition by tardigrade tolerance proteins.
Tanaka, A.; Nakano, T.; Watanabe, K.; Masuda, K.; Kamata, S.; Yasui, R.; Kozuka-Hata, H.; Watanabe, C.; Chinen, T.; Kitagawa, D.; Oyama, M.; Yanagisawa, M.; Kunieda, T.
10.1101/2021.10.02.462891 — biochemistry — Posted on 2021-10-03
3795 Classifying Literature Extracted Events for Automated Model Extension
Hansen, C. E.; Kisslinger, J.; Krishna, N.; Holtzapple, E.; Ahmed, Y.; Miskov-Zivanov, N.
10.1101/2021.09.30.462421 — systems biology — Posted on 2021-10-03
3796 Enzymes degraded under high light maintain proteostasis by transcriptional regulation in Arabidopsis
Li, L.; Duncan, O.; Ganguly, D. R.; Lee, C. P.; Crisp, P. A.; Wijerathna-Yapa, A.; Salih, K.; Trosch, J.; Pogson, B. J.; Millar, A. H.
10.1101/2021.10.03.462903 — plant biology — Posted on 2021-10-03
3799 Increased remodeling and impaired adaption to endurance exercise in desminopathy
Mossakowski, A. A.; Langer, H. T.; Bizieff, A.; Avey, A. M.; Zbinden-Foncea, H.; Hellerstein, M.; Baar, K.
10.1101/2021.10.03.462939 — physiology — Posted on 2021-10-03
3802 Combinatorial Polyacrylamide Hydrogels for Preventing Biofouling on Implantable Biosensors
Chan, D.; Chien, J.-C.; Axpe, E.; Blankemeier, L.; Baker, S. W.; Swaminathan, S.; Piunova, V. A.; Zubarev, D. Y.; Maikawa, C. L.; Grosskopf, A. K.; Mann, J. L.; Soh, H. T.; Appel, E. A.
10.1101/2020.05.25.115675 — bioengineering — Posted on 2021-10-03
3804 DNA dynamics dictates p53 functional outcome
Safieh, J.; Chazan, A.; Vyas, P.; Saleem, H.; Danin-Poleg, Y.; Ron, D.; Haran, T. E.
10.1101/2021.09.18.460898 — biochemistry — Posted on 2021-10-03
3805 Fine-mapping of nuclear compartments using ultra-deep Hi-C shows that active promoter and enhancer elements localize in the active A compartment even when adjacent sequences do not
Gu, H.; Harris, H.; Olshansky, M.; Mohajeri, K.; Eliaz, Y.; Kim, S.; Krishna, A.; Kalluchi, A.; Jacobs, M.; Cauer, G.; Pham, M.; Rao, S.; Dudchenko, O.; Nichols, M. H.; Davis, E. S.; Udupa, D.; Corces, V. G.; Phanstiel, D. H.; Noble, W. S.; Seo, J.-S.; Talkowski, M. E.; Aiden, E. L.; Rowley, M. J.
10.1101/2021.10.03.462599 — genomics — Posted on 2021-10-03
3808 Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition
Serina Secanechia, Y. N.; Bergiers, I.; Rogon, M.; Arnold, C.; Descostes, N.; Le, S.; Lopez Anguita, N.; Ganter, K.; Kapsali, C.; Bouilleau, L.; Gut, A.; Uzuotaite, A.; Aliyeva, A.; Zaugg, J. B.; Lancrin, C.
10.1101/2021.10.03.462906 — developmental biology — Posted on 2021-10-03
3812 Mechanically active integrins direct cytotoxic secretion at the immune synapse
Wang, M. S.; Hu, Y.; Sanchez, E.; Xie, X.; Roy, N. H.; De Jesus, M.; Jin, W.; Lee, J. H.; Hong, Y.; Kim, M.; Kam, L. C.; Salaita, K.; Huse, M.
10.1101/2021.10.02.462778 — immunology — Posted on 2021-10-03
3817 Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model
Brown, H. C.; Beck, S.; Navarro, S.; Di, Y.; Soriano Jerez, E. M.; Kaczmarzyk, J.; Thomas, S. G.; Mirakaj, V.; Watson, S. P.; Nieswandt, B.; Stegner, D.
10.1101/2021.10.03.462933 — physiology — Posted on 2021-10-03
3818 In vivo CRISPRi screen reveals the differential requirement for mitochondrial respiratory chain function between in vivo and in vitro tumor growth
Nakaoka, H.; Bennett, N.; Okimoto, R.; Laurent, D.; Sei, Y.; Bivona, T.; ten Hoeve, J.; Graeber, T.; Nakamura, K.; Nakamura, J.
10.1101/2021.10.03.462937 — cancer biology — Posted on 2021-10-03
3819 Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
Mo, X.; Niu, Q.; Ivanov, A. A.; Tsang, Y. H.; Tang, C.; Shu, C.; Wahafu, A.; Doyle, S.; Cicka, D.; Yang, X.; Fan, D.; Reyna, M. A.; Cooper, L. A. D.; Moreno, C. S.; Zhou, W.; Owonikoko, T.; Lonial, S.; Khuri, F. R.; Du, Y.; Ramalingam, S. S.; Mill, G. B.; Fu, H.
10.1101/2021.10.03.462422 — cancer biology — Posted on 2021-10-03
3821 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, N.; Li, W.; Wang, L. D.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2021-10-03
3822 The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities
Estebanez-Perpina, E.; Jimenez-Panizo, A.; Alegre-Marti, A.; Fettweis, G.; Abella, M.; Anton, R.; Tettey, T.; Schiltz, L. R.; Johnson, T. A.; Nunez-Barrios, I.; Font-Diaz, J.; Caelles, C.; Valledor, A.; Perez, P.; Rojas, A. M.; Fernandez-Recio, J.; Presman, D.; Hager, G. L.; Fuentes-Prior, P.
10.1101/2021.10.01.462734 — biochemistry — Posted on 2021-10-03
3823 New insights into the human 26S proteasome function and regulation
Kisonaite, M.; Afanasyev, P.; Tafilaku, J.; Toste Rego, A.; da Fonseca, P. C. A.
10.1101/2021.10.03.462214 — biochemistry — Posted on 2021-10-03
3825 SUMM4 complex couples insulator function and DNA replication timingcontrol
Andreyeva, E. N.; Emelyanov, A. V.; Nevil, M.; Sun, L.; Vershilova, E.; Hill, C. A.; Keogh, M. C.; Duronio, R. J.; Skoultchi, A. I.; Fyodorov, D. V.
10.1101/2021.10.02.462895 — biochemistry — Posted on 2021-10-03
3826 Genetic basis of body shape variation along the benthic-pelagic axis in cichlid fishes
DeLorenzo, L.; Mathews, D.; Brandon, A. A.; Joglekar, M.; Carmona Baez, A.; Moore, E. C.; Ciccotto, P. J.; Roberts, N. B.; Roberts, R. B.; Powder, K. E.
10.1101/2021.10.02.462884 — evolutionary biology — Posted on 2021-10-03
3827 Cell wall synthesis and remodeling dynamics determine bacterial division site architecture and cell shape
Navarro, P. P.; Vettiger, A.; Ananda, V. Y.; Montero Llopis, P.; Allolio, C.; Bernhardt, T. G.; Chao, L. H.
10.1101/2021.10.02.462887 — microbiology — Posted on 2021-10-03
3828 A NYN domain protein directly interacts with DCP1 and is required for phyllotactic pattern in Arabidopsis.
Schiaffini, M.; Chicois, C.; Pouclet, A.; Chartier, T.; Ubrig, E.; Gobert, A.; Zuber, H.; Mutterer, J.; Chicher, J.; Kuhn, L.; Hammann, P.; Gagliardi, D.; Garcia, D.
10.1101/2021.10.01.462782 — plant biology — Posted on 2021-10-03
3830 Role of the Topoisomerase IIα Chromatin Tether domain in Nucleosome Binding & Chromosome Segregation
Sundararajan, S.; Park, H.; Kawano, S.; Johansson, M.; Saito-Fujita, T.; Saitoh, N.; Arnaoutov, A.; Dasso, M.; Clarke, D.; Azuma, Y.
10.1101/2021.10.03.462934 — cell biology — Posted on 2021-10-03
3832 Direct brain recordings reveal continuous encoding of structure in random stimuli
Fuhrer, J.; Glette, K.; Ivanovic, J.; Larsson, P. G.; Bekinschtein, T. A.; Kochen, S.; Knight, R. T.; Torresen, J.; Solbakk, A.-K. S.; Endestad, T. E.; Blenkmann, A.
10.1101/2021.10.01.462295 — neuroscience — Posted on 2021-10-03
3833 Distinct signatures of loss of consciousness during Focal Impaired Awareness (FIA) versus Focal to Bilateral Tonic-Clonic (FBTC) seizures
Juan, E.; Gorska, U.; Kozma, C.; Papantonatos, C.; Bugnon, T.; Denis, C.; Kremen, V.; Worrell, G.; Struck, A.; Bateman, L.; Merricks, E. M.; Blumenfeld, H.; Tononi, G.; Schevon, C.; Boly, M.
10.1101/2021.10.01.462586 — neuroscience — Posted on 2021-10-03
3835 Stimulating music supports attention in listeners with attentional difficulties
Woods, K. J.; Sempaio, G.; James, T.; Przysinda, E.; Hewett, A.; Spencer, A. E.; Morillon, B.; Loui, P.
10.1101/2021.10.01.462777 — neuroscience — Posted on 2021-10-03
3837 Detection of the 40-Hz Auditory Steady-state Response with Optically Pumped Magnetometers
An, K.-m.; Shim, J. H.; Kwon, H.; Lee, Y.-H.; Yu, K.-K.; Kwon, M.; Chun, W. Y.; Hirosawa, T.; Hasegawa, C.; Iwasaki, S.; Kikuchi, M.; Kim, K.
10.1101/2021.10.01.462598 — neuroscience — Posted on 2021-10-03
3839 A new Mendelian Randomization method to estimate causal effects of multivariable brain imaging exposures
Mo, C.; Ye, Z.; Ke, H.; Lu, T.; Canida, T.; Liu, S.; Wu, Q.; Zhao, Z.; Ma, Y.; Hong, L. E.; Kochunov, P.; Ma, T.; Chen, S.
10.1101/2021.10.01.462221 — bioinformatics — Posted on 2021-10-03
3840 A mechanochemical model recapitulates distinct vertebrate gastrulation modes
Serra, M.; Najera, G. S.; Chuai, M.; Spandan, V.; Weijer, C. J.; Mahadevan, L.
10.1101/2021.10.03.462928 — developmental biology — Posted on 2021-10-03
3842 Local brain-state dependency of effective connectivity: evidence from TMS-EEG
Grano, I.; Mutanen, T. P.; Tervo, A. E.; Nieminen, J. O.; Souza, V. H.; Fecchio, M.; Rosanova, M.; Lioumis, P.; Ilmoniemi, R. J.
10.1101/2021.10.01.462795 — neuroscience — Posted on 2021-10-03
3844 Systems-wide Analysis Revealed Shared and Unique Responses to Moderate and Acute High Temperatures in the Green Alga Chlamydomonas reinhardtii
Zhang, N.; Mattoon, E. M.; McHargue, W.; Venn, B.; Zimmer, D.; Pecani, K.; Jeong, J.; Anderson, C. M.; Chen, C.; Berry, J. C.; Xia, M.; Tzeng, S.-C.; Becker, E.; Pazouki, L.; Evans, B.; Cross, F.; Cheng, J.; Czymmek, K. J.; Schroda, M.; Muhlhaus, T.; Zhang, R.
10.1101/2021.08.17.456552 — plant biology — Posted on 2021-10-03
3845 BioKIT: a versatile toolkit for processing and analyzing diverse types of sequence data
Steenwyk, J. L.; Buida, T. J.; Goncalves, C.; Goltz, D. C.; Morales, G. H.; Mead, M. E.; LaBella, A. L.; Chavez, C. M.; Schmitz, J. E.; Hadjifrangiskou, M.; Li, Y.; Rokas, A.
10.1101/2021.10.02.462868 — bioinformatics — Posted on 2021-10-03
3846 Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo
Zhu, Z.; Waxman, S.; Wang, B.; Wallace, J.; Schmitt, S. E.; Tyler-Kabara, E.; Ishikawa, H.; Schuman, J. S.; Smith, M. A.; Wollstein, G.; Sigal, I. A.
10.1101/2020.12.14.422760 — bioengineering — Posted on 2021-10-03
3848 Sustained post-developmental T-bet expression is critical for the maintenance of type 1 innate lymphoid cells in vivo
Schroeder, J.-H.; Roberts, L. B.; Meissl, K.; Lo, J. W.; Hromadova, D.; Hayes, K.; Zabinski, T.; Read, E.; Moreira Heliodoro, C.; Reis, R.; Howard, J. K.; Grencis, R. K.; Neves, J. F.; Strobl, B.; Lord, G. M.
10.1101/2021.06.05.447200 — immunology — Posted on 2021-10-03
3850 Context-dependent selectivity to natural scenes in the retina
Goldin, M. A.; Lefebvre, B.; Virgili, S.; Ecker, A.; Mora, T.; Ferrari, U.; Marre, O.
10.1101/2021.10.01.462157 — neuroscience — Posted on 2021-10-03
3852 Population-level sensitivity to landscape variables reflects individual-based habitat selection in a woodland bat species
Jan, P.-L.; Zarzoso-Lacoste, D.; Fourcy, D.; Baudouin, A.; Farcy, O.; Boireau, J.; Le Gouar, P.; Puechmaille, S. J.; Petit, E. J.
10.1101/752733 — ecology — Posted on 2021-10-03
3853 Microbial loop of a Proterozoic ocean analogue
Saini, J. S.; Hassler, C.; Cable, R.; Fourquez, M.; Danza, F.; Roman, S.; Tonolla, M.; Storelli, N.; Jacquet, S.; Zdobnov, E. M.; Duhaime, M. B.
10.1101/2021.08.17.456685 — microbiology — Posted on 2021-10-03
3856 Multiscale X-ray study of Bacillus subtilis biofilms reveals interlinked structural hierarchy and elemental heterogeneity
Azulay, D. N.; Spaeker, O.; Ghrayeb, M.; Wilsch-Brauninger, M.; Scoppola, E.; Burghammer, M.; Zizak, I.; Bertinetti, L.; Politi, Y.; Chai, L.
10.1101/2021.07.27.453653 — microbiology — Posted on 2021-10-02
3859 Identification and validation of a non-genetically encoded vulnerability to XPO1 inhibition in malignant rhabdoid tumors - expanding patient-driven discovery beyond the Nof1.
Marks, L. J.; Diolaiti, D.; Mundi, P.; Gaviria, E. S.; Rainey, A. R.; Yamashiro, D. J.; Fazlollahi, L.; Hosoi, H.; Katsumi, Y.; Kuwahara, Y.; Dela Cruz, F. S.; Califano, A.; Kung, A. L.
10.1101/2021.10.02.462793 — cancer biology — Posted on 2021-10-02
3864 Short- and long-read metagenomics of South African gut microbiomes reveal a transitional composition and novel taxa
Tamburini, F. B.; Maghini, D.; Oduaran, O. H.; Brewster, R.; Hulley, M. R.; Sahibdeen, V.; Norris, S. A.; Tollman, S.; Kahn, K.; Wagner, R.; Wade, A. N.; Wafawanaka, F.; Gomez-Olive, X.; Twine, R.; Lombard, Z.; Hazelhurst, S.; Bhatt, A. S.
10.1101/2020.05.18.099820 — genomics — Posted on 2021-10-02
3865 A Budding Yeast Model and Screen to Define the Functional Consequences of Oncogenic Histone Missense Mutations
Lemon, L. D.; Kanna, S.; Mo, K. W.; Adams, M.; Choi, H.; Gulka, A. O. D.; Withers, E. S.; Nurelegne, H. T.; Gomez, V.; Ambrocio, R. E.; Tumminkatti, R.; Lee, R. S.; Fasken, M. B.; Spangle, J. M.; Corbett, A. H.
10.1101/2021.10.02.462853 — genetics — Posted on 2021-10-02
3866 Microbial loop of Proterozoic ocean analogue
Saini, J. S.; Hassler, C.; Cable, R.; Fourquez, M.; Danza, F.; Roman, S.; Tonolla, M.; Storelli, N.; Jacquet, S.; Zdobnov, E. M.; Duhaime, M. B.
10.1101/2021.08.17.456685 — microbiology — Posted on 2021-10-02
3870 Loss of Protein Kinase D2 Activity Protects Against Bleomycin-induced Dermal Fibrosis in Mice
Chen, L.; Zhao, J.; Chao, Y.; Roy, A.; Guo, W.; Qian, J.; Xu, W.; Xing, Z.; Lai, X.; Lu, B.; Deng, F.; Wang, Q. J.
10.1101/2021.10.02.462861 — genetics — Posted on 2021-10-02
3877 Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
Meyers, A. K.; Wang, Z.; Han, W.; Zhao, Q.; Zabalawi, M.; Liu, J.; Manne, R. K.; Lin, H.-K.; Furdui, C. M.; Locasale, J. W.; McCall, C. M.; Zhu, X.
10.1101/2021.10.02.462869 — immunology — Posted on 2021-10-02
3880 Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer's Disease
Javonillo, D. I.; Tran, K. M.; Phan, J.; Hingco, E.; Kramar, E. A.; da Cunha, C.; Forner, S.; Kawauchi, S.; Neumann, J.; Banh, C. E.; Hyunh, M.; Matheos, D. P.; Rezai, N.; Alcantara, J. A.; Mortazavi, A.; Wiid, M. A.; Tenner, A. J.; MacGregor, G.; Green, K. N.; LaFerla, F. M.
10.1101/2021.10.01.462640 — neuroscience — Posted on 2021-10-02
3881 Oral and injected tamoxifen alter adult hippocampal neurogenesis in female and male mice
Smith, B. M.; Saulsbery, A. I.; Sarchet, P.; Devasthali, N.; Einstein, D.; Kirby, E. D.
10.1101/2021.09.30.462662 — neuroscience — Posted on 2021-10-02
3888 Non-conserved metabolic regulation by LKB1 distinguishes human and mouse lung adenocarcinoma
Stein, B. D.; Ferrarone, J. R.; Gardner, E. E.; Chang, J. W.; Wu, D.; Chen, Q.; Hollstein, P. E.; Yuan, M.; Liang, R. J.; Coukos, J. S.; Sindelar, M.; Ngo, B.; Gross, S. S.; Shaw, R. J.; Asara, J. M.; Moellering, R. E.; Varmus, H.; Cantley, L. C.
10.1101/2021.10.01.462764 — cancer biology — Posted on 2021-10-02
3891 Mechanical Compression Creates a Quiescent Muscle Stem Cell Niche
Tao, J.; Choudhury, M. I.; Maity, D.; Kim, T.; Sun, S.; Fan, C.-M.
10.1101/2021.10.02.462865 — biophysics — Posted on 2021-10-02
3894 Plant host shift: The viability and persistence of a polyphagous non-native insect
Bueno Silva, I.; McGrane-Corrigan, B.; Mason, O.; de Andrade Moral, R.; Augusto Conde Godoy, W.
10.1101/2021.09.20.461112 — ecology — Posted on 2021-10-02
3895 Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity
Reinders, A.; Sellner, B.; Fadel, F.; van Berkum, M.; Kaczmarczyk, A.; Ozaki, S.; Rueher, J.; Manfredi, P.; Sangermani, M.; Harms, A.; Perez, C.; Schirmer, T.; Jenal, U.
10.1101/2021.10.01.462762 — microbiology — Posted on 2021-10-02
3897 Anchored and labile pools of Calcineurin are enabled by a disordered AKAP scaffold
Watson, M.; Almeida, T.; Ray, A.; Hanack, C.; Elston, R.; Btesh, J.; McNaughton, P.; Stott, K.
10.1101/2021.05.23.445342 — biophysics — Posted on 2021-10-02
3899 RASopathy Mutations Demonstrate the Critical Function of the Cysteine-rich Domain in Maintaining BRAF in an Autoinhibited State
Spencer-Smith, R.; Terrell, E. M.; Insinna, C.; Agamasu, C.; Wagner, M. E.; Ritt, D. A.; Stauffer, J.; Stephen, A. G.; Morrison, D. K.
10.1101/2021.10.01.462773 — cell biology — Posted on 2021-10-02
3901 Regulation of immune receptor kinases plasma membrane nanoscale landscape by a plant peptide hormone and its receptors
Gronnier, J.; Franck, C. M.; Stegmann, M.; DeFalco, T.; Abarca, A.; Von Arx, M.; Duenser, K.; Lin, W.; Yang, Z.; Kleine-Vehn, J.; Ringli, C.; zipfel, c.
10.1101/2020.07.20.212233 — plant biology — Posted on 2021-10-02
3908 RASopathy Mutations Demonstrate the Critical Function of the Cysteine-rich Domain in Maintaining BRAF in an Autoinhibited State
Spencer-Smith, R.; Terrell, E. M.; Insinna, C.; Agamasu, C.; Wagner, M. E.; Ritt, D. A.; Stauffer, J.; Stephen, A. G.; Morrison, D. K.
10.1101/2021.10.01.462773 — cell biology — Posted on 2021-10-02
3909 Powassan Viruses Spread Cell to Cell During Direct Isolation from IxodesTicks and Persistently Infect Human Brain Endothelial Cells and Pericytes
Conde, J. N.; Sanchez-Vicente, S.; Saladino, N.; Gorbunova, E. E.; Schutt, W. R.; Mladinich, M. C.; Himmler, G.; Benach, J. L.; Kim, H. K.; Mackow, E. R.
10.1101/2021.09.30.462684 — microbiology — Posted on 2021-10-02
3910 Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue
Ojima, K.; Kakegawa, W.; Ito, M.; Miura, Y.; Michibata, Y.; Kubota, R.; Doura, T.; Yamasaki, T.; Miura, E.; Nonaka, H.; Mizuno, S.; Takahashi, S.; Yuzaki, M.; Hamachi, I.; Kiyonaka, S.
10.1101/2021.10.01.462737 — neuroscience — Posted on 2021-10-02
3911 An internal expectation guides Drosophila egg-laying decisions
Vijayan, V.; Wang, Z.; Chandra, V.; Chakravorty, A.; Li, R.; Sarbanes, S. L.; Akhlaghpour, H.; Maimon, G.
10.1101/2021.09.30.462671 — neuroscience — Posted on 2021-10-02
3915 Classifying Literature Extracted Events for Automated Model Extension
Hansen, C. E.; Kisslinger, J.; Krishna, N.; Holtzapple, E.; Ahmed, Y.; Miskov-Zivanov, N.
10.1101/2021.09.30.462421 — systems biology — Posted on 2021-10-01
3918 Characterization of wheat lacking B-type starch granules
Saccomanno, B.; Berbezy, P.; Findlay, K.; Shoesmith, J.; Uauy, C.; Viallis, B.; Trafford, K.
10.1101/2021.10.01.462759 — plant biology — Posted on 2021-10-01
3919 Induction of autotetraploidy and microbiome associations mediate differential responses to pathogens
Mehlferber, E. C.; Song, M. J.; Pelaez, J. N.; Jaenisch, J.; Coate, J. E.; Koskella, B.; Rothfels, C. J.
10.1101/2021.10.01.462589 — plant biology — Posted on 2021-10-01
3920 Time-series Multi-spectral Imaging in Soybean for Improving Biomass and Genomic Prediction Accuracy
Sakurai, K.; Toda, Y.; Kajiya-Kanegae, H.; Ohmori, Y.; Yamasaki, Y.; Takahashi, H.; Takanashi, H.; Tsuda, M.; Tsujimoto, H.; Kaga, A.; Nakazono, M.; Fujiwara, T.; Iwata, H.
10.1101/2021.09.30.462675 — plant biology — Posted on 2021-10-01
3921 Dominant Awn Inhibitor, which encodes an ALOG protein in sorghum, suppresses awn formation in rice
Takanashi, H.; Kajiya-Kanegae, H.; Nishimura, A.; Yamada, J.; Ishimori, m.; Kobayashi, M.; Yano, K.; Iwata, H.; Tsutsumi, N.; Sakamoto, W.
10.1101/2021.09.29.462495 — plant biology — Posted on 2021-10-02
3928 Generation of a molecular interactome of the glioblastoma perivascular niche reveals Integrin Binding Sialoprotein as a key mediator of tumor cell migration
Ghochani, Y.; Sohrabi, A.; Muthukrishnan, S. D. D.; Kawaguchi, R.; Condro, M.; Bastola, S.; Gao, F.; Qin, Y.; Mottahedeh, J.; Arispe, M. L. I.; Rao, N.; Laks, D. R.; Liau, L.; Mathern, G.; Goldman, S.; Carmichael, S. T.; Nakano, I.; Coppola, G.; Seidlits, S.; Kornblum, H.
10.1101/2021.10.01.462643 — cancer biology — Posted on 2021-10-02
3930 Characterization of Cell-Induced Astigmatism in High-Resolution Imaging.
Rodrigues de Mercado, R.; van Hoorn, H.; de Valois, M.; Backendorf, C.; Eckert, J.; Schmidt, T.
10.1101/2021.10.01.462719 — biophysics — Posted on 2021-10-02
3932 SomaticSiMu: a mutational signature simulator
Chen, D.; Randhawa, G. S.; Soltysiak, M. P. M.; de Souza, C. P. E.; Kari, L.; Singh, S. M.; Hill, K.
10.1101/2021.09.30.462618 — bioinformatics — Posted on 2021-10-01
3935 A comprehensive atlas of fetal splicing patterns in the brain of adult myotonic dystrophy type 1 patients
Degener, M. J. F.; van Cruchten, R. T. P.; Otero, B. A.; Wang, E. T.; Wansink, D. G.; 't Hoen, P. A. C.
10.1101/2021.10.01.462715 — bioinformatics — Posted on 2021-10-01
3938 ContaTester: Fast cross-contamination estimation and identification for large human sequencing cohorts
Delafoy, D.; Mercier, J.; Larsonneur, E.; Wiart, N.; Sandron, F.; Mejean, T.; Meslage, S.; Daian, D.; Olaso, R.; Boland, A.; Deleuze, J.-F.; Meyer, V.
10.1101/2021.10.01.461647 — bioinformatics — Posted on 2021-10-02
3939 Fibrillar-Level Strain Gradients Across the Calcified Bone-Cartilage Interface
Badar, W.; Ali, H.; Brooker, O. N.; Newham, E.; Snow, T.; Terrill, N. J.; Tozzi, G.; Fratzl, P.; Knight, M. M.; Gupta, H. S.
10.1101/2021.10.01.462427 — bioengineering — Posted on 2021-10-02
3941 Metformin modulates microbiota-derived inosine and ameliorates methamphetamine-induced anxiety and depression-like withdrawal symptoms in mice
Yang, J.; Zhang, Z.; Xie, Z.; Bai, L.; Xiong, P.; Chen, F.; Zhu, T.; Peng, Q.; Wu, H.; Zhou, Y.; Ma, Y.; Zhang, Y.; Chen, M.; Gao, J.; Tian, W.; Shi, K.; Du, Y.; Duan, Y.; Wang, H.; Xu, Y.; Kuang, Y.-Q.; Yu, J.; Wang, K.
10.1101/2021.09.30.462054 — animal behavior and cognition — Posted on 2021-10-01
3942 A hymenopteran odorant alerts flies to bury eggs
Davis, S. M.; Chism, G. T.; Maurer, M. M.; Trejo, J. E.; Garcia, R. J.; Schlenke, T. A.
10.1101/2021.09.30.462443 — animal behavior and cognition — Posted on 2021-10-01
3945 Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution
Resztak, J. A.; Wei, J.; Zilioli, S.; Sendler, E.; Alazizi, A.; Mair-Meijers, H. E.; Wu, P.; Slatcher, R. B.; Zhou, X.; Luca, F.; Pique-Regi, R.
10.1101/2021.09.30.462672 — genomics — Posted on 2021-10-01
3948 ASIP promoter variants predict sesame coat color in Shiba Inu dogs
Belyakin, S. N.; Maksimov, D. A.; Pobedintseva, M. A.; Laktionov, P. P.; Voronova, D. R.
10.1101/2021.10.01.462523 — genetics — Posted on 2021-10-01
3950 Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures
Gonenc, I. I.; Wolff, A.; Schmidt, J.; Zibat, A.; Muller, C.; Cyganek, L.; Argyriou, L.; Raeschle, M.; Yigit, G.; Wollnik, B.
10.1101/2021.10.01.462717 — genetics — Posted on 2021-10-01
3951 The genome and lifestage-specific transcriptomes of a plant-parasitic nematode and its host reveal susceptibility genes involved in trans-kingdom synthesis of vitamin B.
Siddique, S.; Radakovic, Z. S.; Hiltl, C.; Pellegrin, C.; Baum, T. J.; Beasley, H.; Chitambo, O.; Chopra, D.; Danchin, E. G. J.; Grenier, E.; Habash, S. S.; Hasan, M. S.; Helder, J.; Hewezi, T.; Holbein, J.; Holterman, M.; Janakowski, S.; Koutsovoulos, G. D.; Kranse, O. P.; Lozano-Torres, J. L.; Maier, T. R.; Masonbrink, R. E.; Mendy, B.; Riemer, E.; Sobczak, M.; Sonawala, U.; Sterken, M. G.; Thorpe, P.; van Steenbrugge, J. J. M.; Zahid, N.; Grundler, F.; Eves-van den Akker, S.
10.1101/2021.10.01.462558 — genetics — Posted on 2021-10-01
3952 High-throughput RNA isoform sequencing using programmable cDNA concatenation
Al'Khafaji, A. M.; Smith, J. T.; Garimella, K. V.; Babadi, M.; Sade-Feldman, M.; Gatzen, M.; Sarkizova, S.; Schwartz, M. A.; Popic, V.; Blaum, E. M.; Day, A.; Costello, M.; Bowers, T.; Gabriel, S.; Banks, E.; Philippakis, A. A.; Boland, G. M.; Blainey, P. C.; Hacohen, N.
10.1101/2021.10.01.462818 — genetics — Posted on 2021-10-01
3958 Blood variation implicates respiratory limits on elevational ranges of Andean birds
Linck, E. B.; Williamson, J.; Bautista, E.; Beckman, E.; Benham, P. M.; DuBay, S. G.; Flores, L. M.; Gadek, C. R.; Johnson, A. B.; Jones, M. R.; Nunez-Zapata, J.; Quinonez, A.; Schmitt, C. J.; Susanibar, D.; Tiravanti C, J.; Verde-Guerra, K.; Wright, N. A.; Valqui, T.; Storz, J. F.; Witt, C. C.
10.1101/2021.09.30.462673 — ecology — Posted on 2021-10-01
3961 INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury
Calabrese, B.; Jones, S.; Yamaguchi-Shiraishi, Y.; Lingelbach, M. J.; Manor, U.; Svitkina, T. M.; Higgs, H. N.; Shih, A. Y.; Halpain, S.
10.1101/2021.10.01.462790 — cell biology — Posted on 2021-10-01
3962 JADE family proteins regulate proteasome abundance and activity
Ebert, L. K.; Bargfrede, S.; Bohl, K.; Mueller, R.-U.; Benzing, T.; Schermer, B.
10.1101/2021.10.01.462752 — cell biology — Posted on 2021-10-01
3963 Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors
Wu, C.; Boey, D.; Bril, O.; Grootens, J.; Vijayabaskar, M. S.; Sorini, C.; Ekoff, M.; Wilson, N. K.; Ungerstedt, J. S.; Nilsson, G.; Dahlin, J. S.
10.1101/2021.10.01.462521 — cell biology — Posted on 2021-10-01
3965 Long-term analysis of pertussis vaccine immunity uncovers a memory B cell response to whole cell pertussis immunization that is absent from acellular immunized mice
Weaver, K. L.; Blackwood, C. B.; Horspool, A. M.; Pyles, G. M.; Sen-Kilic, E.; Grayson, E. M.; Huckaby, A. B.; Witt, W. T.; DeJong, M. A.; Wolf, M. A.; Damron, F. H.; Barbier, M.
10.1101/2021.10.01.462695 — immunology — Posted on 2021-10-01
3966 Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors
Angkeow, J. W.; Monaco, D. R.; Chen, A.; Venkataraman, T.; Jayaraman, S.; Valencia, C.; Sie, B. M.; Liechti, T.; Farhadi, P. N.; Funez-dePagnier, G.; Sherman-Baust, C. A.; Wong, M. Q.; Sears, C. L.; Simner, P. J.; Round, J. L.; Duggal, P.; Laserson, U.; Steiner, T. S.; Sen, R.; Lloyd, T. E.; Roederer, M.; Mammen, A. L.; Longman, R. S.; Rider, L. G.; Larman, H. B.
10.1101/2021.10.01.462481 — immunology — Posted on 2021-10-02
3967 Small, correlated changes in synaptic connectivity may facilitate rapid motor learning
Feulner, B.; Perich, M. G.; Chowdhury, R. H.; Miller, L. E.; Gallego, J. A.; Clopath, C.
10.1101/2021.10.01.462728 — neuroscience — Posted on 2021-10-01
3968 An Approach to Measuring Protein Turnover in Human Induced Pluripotent Stem Cell Organoids by Mass Spectrometry
Duchesne, A.; Dong, J.; Bayne, A. N.; Mohamed, N.-V.; Yi, W.; Mathur, M.; Fon, E. A.; Durcan, T. M.; Trempe, J.-F.
10.1101/2021.09.30.462679 — neuroscience — Posted on 2021-10-01
3972 Topographic connectivity and cellular profiling reveal detailed input pathways and functionally distinct cell types in the subthalamic nucleus
Jeon, H.; Lee, H.; Kwon, D.-H.; Kim, J.; Tanaka-Yamamoto, K.; Feng, L.; Park, H.; Lim, Y. H.; Cho, Z.-H.; Paek, S. H.; Kim, J.
10.1101/2021.10.01.462690 — neuroscience — Posted on 2021-10-01
3974 Functional characterisation of single nucleotide variants of the psychiatric risk gene cacna1c in the zebrafish
Banono, N. S.; Gawel, K.; Maki-Marttunen, T.; van der Ent, W.; Kukula-Koch, W.; Fyhn, M.; Einevoll, G. T.; Andreassen, O. A.; Esguerra, C. V.
10.1101/2021.09.30.462600 — neuroscience — Posted on 2021-10-01
3975 Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks
Dudek, M.; Pathiranage, D.; Goncalves, C. F.; Lawless, C.; Wang, D.; Luo, Z.; Yang, L.; Hoyland, J. A.; Meng, Q.-J.
10.1101/2021.10.01.462769 — physiology — Posted on 2021-10-01
3977 EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma
Showpnil, I. A.; Selich-Anderson, J.; Taslim, C.; Boone, M. A.; Crow, J. C.; Theisen, E. R.; Lessnick, S. L.
10.1101/2021.09.30.462658 — cancer biology — Posted on 2021-10-01
3978 Combined PI3K and MLL inhibition synergizes in models of HR+ breast cancer
Jones, R. B.; Farhi, J.; Zecevic, M.; Parwani, K.; Adams, M.; Lee, R. S.; Spangle, J.
10.1101/2021.10.01.462826 — cancer biology — Posted on 2021-10-01
3979 Chi3l1 is a modulator of glioma stem cell states and a therapeutic vulnerability for glioblastoma
Guetta-Terrier, C.; Karambizi, D.; Akosman, B.; Chen, J.-S.; Kamle, S.; Fajardo, J. E.; Fiser, A.; Singh, R.; Toms, S. A.; Lee, C. G.; Elias, J. A.; Tapinos, N.
10.1101/2021.10.01.462786 — cancer biology — Posted on 2021-10-01
3982 CellDepot: A unified repository for scRNA-seq data and visual exploration
Lin, D.; Chen, Y.; Negi, S.; Cheng, D.; Ouyang, Z.; Sexton, D.; Li, K.; Zhang, B.
10.1101/2021.09.30.462602 — bioinformatics — Posted on 2021-10-01
3986 Localization free super-resolution microbubble velocimetry using a long short-term memory neural network
Chen, X.; Lowerison, M.; Dong, Z.; Sekaran, N. C.; Huang, C.; Chen, S.; Fan, T. M.; Llano, D. A.; Song, P.
10.1101/2021.10.01.462404 — bioengineering — Posted on 2021-10-01
3988 Cell-Penetrating D-Peptides Retain Antisense Morpholino Oligomer Delivery Activity
Schissel, C. K.; Farquhar, C. E.; Malmberg, A. B.; Loas, A. I.; Pentelute, B. L.
10.1101/2021.09.30.462617 — bioengineering — Posted on 2021-10-01
3999 ModelMatcher: A scientist-centric online platform to facilitate collaborations between stakeholders of rare and undiagnosed disease research
Harnish, J. M.; Li, L.; Rogic, S.; Poirier-Morency, G.; Kim, S.-Y.; Undiagnosed Diseases Network, ; Boycott, K. M.; Wangler, M. F.; Bellen, H. J.; Hieter, P.; Pavlidis, P.; Liu, Z.; Yamamoto, S.
10.1101/2021.09.30.462504 — genetics — Posted on 2021-10-01
4000 The complex genetics of symbiotic extended phenotypes across environments in a model mutualism
Batstone, R. T.; Lindgren, H. K.; Allsup, C. M.; Goralka, L. A.; Riley, A. B.; Grillo, M. A.; Marshall-Colon, A.; Heath, K.
10.1101/2021.08.03.454976 — evolutionary biology — Posted on 2021-10-01
4001 Effects of productive management of an agroforestry system on the associated diversity of parasitoids (Hymenoptera: Braconidae)
Pech Cutis, C. M.; Castillo Sanchez, L. E.; Canul Solis, J. R.; Coba, E. L.; Ruz Febles, N. M.; Campos-Navarrete, M. J.
10.1101/2021.10.01.462815 — ecology — Posted on 2021-10-01
4002 Direct Reprogramming of Non-limb Fibroblasts toCells with Properties of Limb Progenitors
Atsuta, Y.; Lee, C.; Rodrigues, A. R.; Colle, C.; Tomizawa, R. R.; Lujan, E. G.; Tschopp, P.; Gorham, J. M.; Vannier, J.-P.; Seidman, C.; Seidman, J. G.; Pourquie, O.; Tabin, C.
10.1101/2021.10.01.462632 — developmental biology — Posted on 2021-10-01
4003 ERK signaling dissolves ERF Repression Condensates in Living Embryos
Weaver, C. J.; Patel, A. L.; Shvartsman, S. Y.; Levine, M. S.; Treen, N.
10.1101/2021.10.01.462829 — developmental biology — Posted on 2021-10-01
4007 Emergence of task information from dynamic network interactions in the human brain
Mill, R. D.; Hamilton, J. L.; Winfield, E. C.; Lalta, N.; Chen, R. H.; Cole, M. W.
10.1101/2021.01.26.428276 — neuroscience — Posted on 2021-10-01
4008 Natural and designed proteins inspired by extremotolerant organisms can form condensates and attenuate apoptosis in human cells
Veling, M. T.; Nguyen, D. T.; Thadani, N. N.; Oster, M. E.; Rollins, N. J.; Brock, K. P.; Bethel, N. P.; Baker, D.; Way, J. C.; Marks, D. S.; Chang, R. L.; Silver, P. A.
10.1101/2021.10.01.462432 — synthetic biology — Posted on 2021-10-01
4010 Improving the global dimensions of intrinsically disordered proteins in Martini 3
Thomasen, F. E.; Pesce, F.; Roesgaard, M. A.; Tesei, G.; Lindorff-Larsen, K.
10.1101/2021.10.01.462803 — biophysics — Posted on 2021-10-01
4013 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, N.; Li, W.; Wang, L. D.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2021-10-01
4014 Role of Ring6 in the function of the E. coli MCE protein LetB
Vieni, C.; Coudray, N.; Isom, G. L.; Bhabha, G.; Ekiert, D. C.
10.1101/2021.09.30.462657 — biochemistry — Posted on 2021-10-01
4016 Deep mutational scan of a drug efflux pump reveals its structure-function landscape
Meier, G.; Thavarasah, S.; Ehrenbolger, K.; Hutter, C. A. J.; Hürlimann, L. M.; Barandun, J.; Seeger, M. A.
10.1101/2021.10.01.462730 — biochemistry — Posted on 2021-10-01
4018 Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling
Zimmerman, S. M.; Fropf, R.; Kulasekara, B. R.; Griswold, M.; Appelbe, O.; Bahrami, A.; Boykin, R.; Buhr, D. L.; Fuhrman, K.; Hoang, M. L.; Huynh, Q.; Isgur, L.; Klock, A.; Kutchma, A.; Lasley, A. E.; Liang, Y.; McKay-Fleisch, J.; Nguyen, K.; Piazza, E.; Rininger, A.; Zollinger, D. R.; Rhodes, M.; Beechem, J. M.
10.1101/2021.09.29.462442 — genomics — Posted on 2021-10-01
4025 Structural basis of ATP-dependent high-fidelity epigenome maintenance
Wang, J.; Catania, S.; Wang, C.; de la Cruz, M. J.; Rao, B.; Madhani, H. D.; Patel, D. J.
10.1101/2021.10.01.462825 — molecular biology — Posted on 2021-10-01
4026 Fundamentals of Vaping-Associated Pulmonary Injury Leading to Severe Respiratory Distress
Esquer, C.; Echeagaray, O.; Firouzi, F.; Savko, C.; Shain, G.; Bose, P.; Rieder, A.; Rokaw, S.; Witon-Paulo, A.; Gude, N.; Sussman, M. A.
10.1101/2021.10.01.461568 — molecular biology — Posted on 2021-10-01
4027 Fungal Mineral Weathering Mechanisms Revealed Through Direct Molecular Visualization
Bhattacharjee, A.; Qafoku, O.; Richardson, J. A.; Anderson, L. N.; Schwarz, K.; Bramer, L. M.; Lomas, G. X.; Orton, D. J.; Zhu, Z.; Engelhard, M. H.; Bowden, M. E.; Nelson, W. C.; Jumpponen, A.; Jansson, J. K.; Hofmockel, K. S.; Anderton, C. R.
10.1101/2021.10.01.462718 — microbiology — Posted on 2021-10-01
4030 Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity
Reinders, A.; Sellner, B.; Fadel, F.; van Berkum, M.; Kaczmarczyk, A.; Ozaki, S.; Rueher, J.; Manfredi, P.; Sangermani, M.; Harms, A.; Perez, C.; Schirmer, T.; Jenal, U.
10.1101/2021.10.01.462762 — microbiology — Posted on 2021-10-01
4032 New insights into the architecture and dynamics of archaella
Gambelli, L.; Isupov, M. N.; Conners, R.; McLaren, M.; Bellack, A.; Gold, V.; Rachel, R.; Daum, B.
10.1101/2021.10.01.462426 — microbiology — Posted on 2021-10-01
4034 OXPHOS Promotes Apoptotic Resistance and Persistence in TH17 cells
Hong, H.; Mbah, N.; Shan, M.; Loesel, K.; Lin, L.; Sajjakulnukit, P.; Andren, A.; Hayashi, A.; Magnuson, B.; Li, Z.; Xie, Y.; Zhang, L.; Lei, Y. L.; Opipari, A.; Arguello, R. J.; Kryczek, I.; Kamada, N.; Zou, W.; Franchi, L.; Lyssiotis, C. A.
10.1101/2021.10.01.462812 — immunology — Posted on 2021-10-01
4035 Efficient methods for generation and expansion of, and gene delivery to Rhesus Macaque plasma B cells
Kreuser, S.; Honaker, Y.; Cheng, R. Y.-H.; Dahl, N.; Soligalla, R.; Lopez, C.; Rawlings, D. J.; James, R. G.
10.1101/2021.09.30.462595 — immunology — Posted on 2021-10-01
4036 Neutrophils contribute to ER stress in lung epithelial cells in the pristane-induced diffuse alveolar hemorrhage mouse model
Tumurkhuu, G.; Ercan Laguna, D.; Moore, R. E.; Contreras, J.; De Los Santos, G.; Akaveka, L.; Montano, E. N.; Wang, Y.; Ishimori, M.; Venuturupalli, S.; Forbess, L.; Wallace, D. J.; Jefferies, C. A.
10.1101/2021.10.01.462788 — immunology — Posted on 2021-10-01
4039 A Developmental Reduction of the Excitation:Inhibition Ratio in Association Cortex during Adolescence.
Larsen, B.; Cui, Z.; Adebimpe, A.; Pines, A. R.; Alexander-Bloch, A.; Bertolero, M.; Calkins, M. E.; Gur, R. E.; Gur, R. C.; Mahadevan, A. S.; Moore, T. M.; Roalf, D. R.; Seidlitz, J.; Sydnor, V. J.; Wolf, D. H.; Satterthwaite, T. D.
10.1101/2021.05.19.444703 — neuroscience — Posted on 2021-10-01
4041 Odor motion sensing enables complex plume navigation
Kadakia, N.; Demir, M.; Michaelis, B. T.; Reidenbach, M. A.; Clark, D. A.; Emonet, T.
10.1101/2021.09.29.462473 — neuroscience — Posted on 2021-10-01
4045 Myofibril orientation as a metric for characterizing heart disease
Ma, W.; Gong, H.; Jani, V.; Landim-Vieira, M.; Papadaki, M.; Pinto, J.; Aslam, M. I.; Cammarato, A.; Irving, T.
10.1101/2021.09.24.461697 — biophysics — Posted on 2021-10-01
4047 Specificity of Gβ and γ subunits to the SNARE complex both at rest and after α2aadrenergic receptor stimulation
Yim, Y. Y.; McDonald, W. H.; Betke, K. M.; Kaya, A.; Hyde, K.; Erreger, K.; Gilsbach, R.; Hein, L.; Hamm, H. E.
10.1101/2020.04.29.065136 — biochemistry — Posted on 2021-10-01
4048 Optimized Workflow for High Spatial Resolution MALDI Imaging Mass Spectrometry ofFresh-Frozen Bone
Good, C. J.; Neumann, E. K.; Butrico, C. E.; Cassat, J. E.; Caprioli, R. M.; Spraggins, J. M.
10.1101/2021.10.01.462831 — biochemistry — Posted on 2021-10-01
4050 Comparison of Plaque Size, Thermal Stability, and Replication Rate among SARS-CoV-2 Variants of Concern
Jeong, G. U.; Yoon, G. Y.; Moon, H. W.; Lee, W.; Hwang, I.; Kim, H. S.; Kim, K.-D.; Kim, C.; Ahn, D.-G.; Kim, B.-T.; Kim, S.-J.; Kwon, Y.-C.
10.1101/2021.09.30.462687 — microbiology — Posted on 2021-10-01
4051 ZBP1 induces inflammatory signaling via RIPK3 and promotes SARS-CoV-2-induced cytokine expression
Peng, R.; Wang-Kan, X.; Idorn, M.; Zhou, F. Y.; Orozco, S. L.; McCarthy, J.; Leung, C. S.; Lu, X.; Bagola, K.; Rehwinkel, J.; Oberst, A.; Maelfait, J.; Paludan, S. R.; Gyrd-Hansen, M.
10.1101/2021.10.01.462460 — immunology — Posted on 2021-10-01
4052 Work Flows for Cellular Epidemiology, From Conception to Translation
Nathanson, A. D.; Ngo, L.; Garbowski, T.; Srikantha, A.; Wojek, C.; Zeidler, D.; Knothe Tate, M.
10.1101/548412 — physiology — Posted on 2021-10-01
4055 Isotopic evidence for population dynamics in the Central Italian Copper Age and Bronze Age.
Romboni, M.; Arienzo, I.; Di Vito, M. A.; Lubritto, C.; Piochi, M.; Di Cicco, M. R.; Rickards, O.; Rolfo, M. F.; Sevink, J.; De Angelis, F.; Alessandri, L.
10.1101/2021.09.30.462554 — evolutionary biology — Posted on 2021-10-01
4057 Knockout of a single Sox gene resurrects an ancestral cell type in the sea anemone Nematostella vectensis
Babonis, L. S.; Enjolras, C.; Reft, A. J.; Foster, B. M.; Hugosson, F.; Ryan, J. F.; Daly, M.; martindale, m. q.
10.1101/2021.09.30.462561 — evolutionary biology — Posted on 2021-10-01
4059 Hippocampal CA1 pyramidal cells do not receive monosynaptic input from thalamic nucleus reuniens
Andrianova, L.; Brady, E. S.; Margetts-Smith, G.; Kohli, S.; McBain, C. J.; Craig, M. T.
10.1101/2021.09.30.462517 — neuroscience — Posted on 2021-10-01
4060 Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability
Cibelli, A.; Stout, R.; Timmermann, A.; de Menezes, L.; Guo, P.; Maass, K.; Seifert, G.; Steinhaeuser, C.; Spray, D. C.; Scemes, E.
10.1101/2021.09.30.462547 — neuroscience — Posted on 2021-10-01
4062 A morphometric double dissociation: cortical thickness is more related to aging; surface area is more related to cognition
Borgeest, S.; Henson, R. N.; Kietzmann, T. C.; Madan, C. R.; Fox, T.; Malpetti, M.; Fuhrmann, D.; Knights, E.; Carlin, J. D.; Cam-CAN, ; Kievit, R. A.
10.1101/2021.09.30.462545 — neuroscience — Posted on 2021-10-01
4066 Climatic clustering and longitudinal analysis with impacts on food, bioenergy, and pandemics
Lagergren, J. H.; Cashman, M.; Melesse Vergara, V. G.; Eller, P.; Gazolla, J. G. F. M.; Chhetri, H. B.; Streich, J.; Climer, S. H.; Thornton, P.; Joubert, W.; Jacobson, D.
10.1101/2021.09.30.462568 — systems biology — Posted on 2021-10-01
4069 interpolatedXY: a two-step strategy to normalise DNA methylation microarray data avoiding sex bias
Wang, Y.; Gorrie-Stone, T. J.; Grant, O. A.; Andrayas, A. D.; Zhai, X.; McDonald-Maier, K. D.; Schalkwyk, L. C.
10.1101/2021.09.30.462546 — bioinformatics — Posted on 2021-10-01
4070 MoSBi: Automated signature mining for molecular stratification and subtyping
Rose, T. D.; Bechtler, T.; Ciora, O.-A.; Anh Lilian Le, K.; Molnar, F.; Koehler, N.; Baumbach, J.; Roettger, R.; Pauling, J. K.
10.1101/2021.09.30.462567 — bioinformatics — Posted on 2021-10-01
4071 Tissue engineered organoid co-culture model of the cycling human endometrium in a fully-defined synthetic extracellular matrix
Gnecco, J. S.; Brown, A. T.; Buttrey, K.; Ives, C. S.; Goods, B. A.; Baugh, L.; Hernandez-Gordillo, V.; Loring, M.; Isaacson, K.; Griffith, L. G.
10.1101/2021.09.30.462577 — bioengineering — Posted on 2021-10-01
4076 Structural mapping of antibody landscapes to human betacoronavirus spike proteins
Bangaru, S.; Antanasijevic, A.; Kose, N.; Sewall, L. M.; Jackson, A. M.; Suryadevara, N.; Zhan, X.; Torres, J. L.; Copps, J.; Torrents de la Pena, A.; Crowe, J. E.; Ward, A. B.
10.1101/2021.09.30.462459 — immunology — Posted on 2021-10-01
4077 Serum glycoprotein markers in non-alcoholic steatohepatitis and hepatocellular carcinoma
Ramachandran, P.; Xu, G.; Huang, H. H.-L.; Rice, R.; Zhou, B.; Lindpaintner, K.; Serie, D.
10.1101/2021.09.30.462486 — cancer biology — Posted on 2021-10-01
4079 Bioactive isoprenoids guide migrating germ cells to the embryonic gonad
Barton, L.; Sanny, J.; Dawson, E. P.; Nouzova, M.; Noriega, F. G.; Stadtfeld, M.; Lehmann, R.
10.1101/2021.09.30.462471 — developmental biology — Posted on 2021-10-01
4080 Enhancers of host immune tolerance to bacterial infection discovered using linked computational and experimental approaches
Sperry, M. M.; Novak, R.; Keshari, V.; Dinis, A. L.; Cartwright, M. J.; Camacho, D. M.; Pare, J.-F.; Super, M.; Levin, M.; Ingber, D. E.
10.1101/2021.09.30.462576 — immunology — Posted on 2021-10-01
4083 In Vivo Generation of Bone Marrow from Embryonic Stem Cells in Interspecies Chimeras
Wen, B.; Wang, G.; Li, E.; Kolesnichenko, O. A.; Tu, Z.; Divanovic, S.; Kalin, T. V.; Kalinichenko, V. V.
10.1101/2021.09.30.462528 — developmental biology — Posted on 2021-10-01
4085 Astrocytic extracellular vesicles modulate neuronal calcium homeostasis via transglutaminase-2
Tonoli, E.; Verduci, I.; Prada, I.; Forcaia, G.; Gabrielli, M.; Coveney, C.; Savoca, M. P.; Boocock, D. J.; Sancini, G.; Mazzanti, M.; Verderio, C.; Verderio, E. A. M.
10.1101/2021.09.30.462507 — neuroscience — Posted on 2021-10-01
4086 Integrated Regulation of PKA by Fast and Slow Neurotransmission in the Nucleus Accumbens Controls Plasticity and Stress Responses
Thomas, R.; Hernandez, A.; Benavides, D. R.; Li, W.; Tan, C.; Plattner, F.; Chakraborti, A.; Pozzo-Miller, L.; Taylor, S. S.; Bibb, J. A.
10.1101/2021.09.29.462408 — neuroscience — Posted on 2021-10-01
4087 Genomics Characterization of an Engineered Corynebacterium glutamicum in Bioreactor Cultivation under Ionic Liquid Stress
Banerjee, D.; Eng, T.; Sasaki, Y.; Srinivasan, A.; Oka, A.; Herbert, R. A.; Trinh, J.; Singan, V. R.; Sun, N.; Putnam, D.; Scown, C. D.; Simmons, B. A.; Mukhopadhyay, A.
10.1101/2021.09.29.462453 — systems biology — Posted on 2021-10-01
4093 S. pombe wtf genes use dual transcriptional regulation and selective protein exclusion from spores to cause meiotic drive
Nuckolls, N. L.; Nidamangala Srinivasa, A.; Mok, A. C.; Bravo Nunez, M. A.; Lange, J. J.; Gallagher, T. J.; Seidel, C. W.; Zanders, S.
10.1101/2021.09.30.462505 — genetics — Posted on 2021-10-01
4094 Nup358 regulates remodelling of ER-mitochondrial contact sites and autophagy
Kalarikkal, M.; Saikia, R.; Varshney, P.; Dhamale, P.; Majumdar, A.; Joseph, J.
10.1101/2021.10.01.462723 — cell biology — Posted on 2021-10-01
4095 A genome-wide genetic screen uncovers novel determinants of human pigmentation
Bajpai, V. K.; Swigut, T.; Mohammed, J.; Tycko, J.; Naqvi, S.; Arreola, M.; Kim, T.; Arora, N.; Pritchard, J. K.; Bassik, M. C.; Wyscoka, J.
10.1101/2021.09.29.462413 — cell biology — Posted on 2021-10-01
4096 Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms
Boudehen, Y.-M.; Faucher, M.; Marechal, X.; Miras, R.; Rech, J.; Seneque, O.; Wallat, M.; Demange, P.; Bouet, J.-Y.; Saurel, O.; Catty, P.; Gutierrez, C.; Neyrolles, O.
10.1101/2021.10.01.462712 — microbiology — Posted on 2021-10-01
4097 A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex
Yao, S.; Wang, Q.; Hirokawa, K. E.; Ouellette, B.; Ahmed, R.; Bomben, J.; Brouner, K.; Casal, L.; Caldejon, S.; Cho, A.; Dotson, N. I.; Daigle, T. L.; Egdorf, T.; Enstrom, R.; Gary, A.; Gelfand, E.; Gorham, M.; Griffin, F.; Gu, H.; Hancock, N.; Howard, R.; Kuan, L.; Lambert, S.; Lee, E. K.; Luviano, J.; Mace, K.; Maxwell, M.; Mortrud, M. T.; Naeemi, M.; Nayan, C.; Ngo, N.-K.; Nguyen, T.; North, K.; Ransford, S.; Ruiz, A.; Seid, S.; Swapp, J.; Taormina, M. J.; Wakeman, W.; Zhou, T.; Nicovich, P. R.; Williford, A.; Potekhina, L.; McGraw, M.; Ng, L.; Groblewski, P. A.; Tasic, B.; Mihalas, S.; Har
10.1101/2021.09.29.459010 — neuroscience — Posted on 2021-10-01
4098 Distance estimation from monocular cues in an ethological visuomotor task
Parker, P. R. L.; Abe, E. T. T.; Beatie, N. T.; Leonard, E. S. P.; Martins, D. M.; Sharp, S. L.; Wyrick, D. G.; Mazzucato, L.; Niell, C. M.
10.1101/2021.09.29.462468 — neuroscience — Posted on 2021-10-01
4099 Intravital imaging of cerebral microinfarct reveals an astrocyte reaction led to glial scar
Lee, J.; Kim, J.-G.; Hong, S.; Kim, Y. S.; Ahn, S.; Kim, R.; Chun, H.; Park, K. D.; Jeong, Y.; Kim, D.-E.; Lee, C. J.; Ku, T.; Kim, P.
10.1101/2021.09.29.462492 — neuroscience — Posted on 2021-10-01
4102 Structural basis for the absence of low-energy chlorophylls responsible for photoprotection from a primitive cyanobacterial PSI
Kato, K.; Hamaguchi, T.; Nagao, R.; Kawakami, K.; Ueno, Y.; Suzuki, T.; Uchida, H.; Murakami, A.; Nakajima, Y.; Yokono, M.; Akimoto, S.; Dohmae, N.; Yonekura, K.; Shen, J.-R.
10.1101/2021.09.29.462462 — plant biology — Posted on 2021-10-01
4103 Dominant Awn Inhibitor, which encodes an ALOG protein in sorghum, suppresses awn formation in rice
Takanashi, H.; Kajiya-Kanegae, H.; Nishimura, A.; Yamada, J.; Ishimori, m.; Kobayashi, M.; Yano, K.; Iwata, H.; Tsutsumi, N.; Sakamoto, W.
10.1101/2021.09.29.462495 — plant biology — Posted on 2021-10-01
4105 Female fruit flies cannot protect stored sperm from high temperature damage
Walsh, B. S.; Parratt, S. R.; Snook, R. R.; Bretman, A.; Atkinson, D.; Price, T. A. R.
10.1101/2021.09.30.462530 — physiology — Posted on 2021-10-01
4107 Cellular mechanisms of heterogeneity in NF2-mutant schwannoma
MacKenzie, C. C.; Liu, C. H.; Vitte, J.; Flynn, E. A.; Stott, S. L.; Giovannini, M.; McClatchey, A. I.
10.1101/2020.12.31.424999 — cancer biology — Posted on 2021-10-01
4108 Revisiting colorectal cancer tumorigenesis with spatially-resolved gene expression profiling
Roelands, J.; van der Ploeg, M.; Dang, H.; Boonstra, J. J.; Hardwick, J. C. H.; Hawinkels, L. J. A. C.; Morreau, H.; de Miranda, N.
10.1101/2021.09.30.462502 — cancer biology — Posted on 2021-10-01
4112 Characterization of new recombinant Immunoglobulins type-M binding to C1q by Biolayer Interferometry
Chouquet, A.; Pinto, A. J.; Ling, W. L. W.; Hennicke, J.; Bally, I.; Schwaigerlehner, L.; Thielens, N. M.; Kunert, R.; REISER, J.-B.
10.1101/2021.09.30.460443 — bioengineering — Posted on 2021-10-01
4113 Augmented Transcutaneous Stimulation Using an Injectable Electrode
Verma, N.; Graham, R. D.; Mudge, J.; Trevathan, J. K.; Franke, M.; Shoffstall, A. J.; Williams, J.; Dalrymple, A. N.; Fisher, L. E.; Weber, D. J.; Lempka, S. F.; Ludwig, K. A.
10.1101/2021.09.29.462482 — bioengineering — Posted on 2021-10-01
4114 Sexual and temporal variation in New Zealand bellbird song repertoires
Roper, M. M.; Webb, W. H.; Fukuzawa, Y.; Evans, C.; Harmer, A. M. T.; Brunton, D. H.
10.1101/2021.09.29.462458 — animal behavior and cognition — Posted on 2021-10-01
4115 Single-cell and nucleus RNA-seq in a mouse model of AD reveal activation of distinct glial subpopulations in the presence of plaques and tangles
Balderrama-Gutierrez, G.; Liang, H.; Rezaie, N.; Carvalho, K.; Forner, S.; Mattheos, D.; Rebboah, E.; Green, K. N.; Tenner, A. J.; LaFerla, F.; Mortazavi, A.
10.1101/2021.09.29.462436 — genomics — Posted on 2021-10-01
4116 Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling
Zimmerman, S. M.; Fropf, R.; Kulasekara, B. R.; Griswold, M.; Appelbe, O.; Bahrami, A.; Boykin, R.; Buhr, D. L.; Fuhrman, K.; Hoang, M. L.; Huynh, Q.; Isgur, L.; Klock, A.; Kutchma, A.; Lasley, A. E.; Liang, Y.; McKay-Fleisch, J.; Nguyen, K.; Piazza, E.; Rininger, A.; Zollinger, D. R.; Rhodes, M.; Beechem, J. M.
10.1101/2021.09.29.462442 — genomics — Posted on 2021-10-01
4119 Deficiency of ZC3HC1 increases vascular smooth muscle cell migration, proliferation and neointima formation following injury
Aherrahrou, R.; Reinberger, T.; Werner, J.; Otto, M.; Al-Hasani, J.; Munoz-Venegas, L.; Civelek, M.; Schunkert, H.; Kessler, T.; Erdmann, J.; Aherrahrou, Z.
10.1101/2021.09.29.462212 — genetics — Posted on 2021-10-01
4120 Plasticity in female timing may explain current shifts in breeding phenology of a North American songbird
Kimmitt, A. A.; Becker, D. J.; Diller, S. N.; Gerlach, N. M.; Rosvall, K. A.; Ketterson, E. D.
10.1101/2021.09.29.462407 — ecology — Posted on 2021-10-01
4124 A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant-negative impact on CSF1R signaling.
Stables, J.; Green, E. K.; Sehgal, A.; Patkar, O.; Keshvari, S.; Taylor, I.; Ashcroft, M. E.; Grabert, K.; Wollscheid-Lengeling, E.; Szymkowiak, S.; McColl, B. A.; Adamson, A.; Humphreys, N.; Mueller, W.; Starobova, H.; Vetter, I.; Kiani Shabestari, S.; Blurton-Jones, M.; Summers, K. M.; Irvine, K. M.; Pridans, C.; Hume, D. A.
10.1101/2021.09.29.462493 — developmental biology — Posted on 2021-10-01
4126 KRAB Zinc Finger protein Znf684 interacts with Nxf1 to regulate mRNA export
Nitoiu, A.; Nabeel-Shah, S.; Farhangmehr, S.; Pu, S.; Braunschweig, U.; Blencowe, B. J.; Greenblatt, J.
10.1101/2021.09.29.462476 — molecular biology — Posted on 2021-10-01
4127 A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing
EL FATIMY, R.; Zhang, Y.; Deforzh, E.; Ramadas, M.; Saravanan, H.; Wei, Z.; Rabinovsky, R.; Teplyuk, N. M.; Uhlmann, E. J.; Krichevsky, A. M.
10.1101/2021.09.30.462508 — molecular biology — Posted on 2021-10-01
4128 The proSAAS chaperone provides neuroprotection and attenuates transsynaptic α-synuclein spread in rodent models of Parkinson's disease
Lindberg, I.; Shu, Z.; Lam, H.; Helwig, M.; Yucer, N.; Laperle, A.; Svendsen, C.; Di Monte, D.; Maidment, N. T.
10.1101/2021.09.29.462435 — neuroscience — Posted on 2021-10-01
4130 Odor motion sensing enables complex plume navigation
Kadakia, N.; Demir, M.; Michaelis, B. T.; Reidenbach, M. A.; Clark, D. A.; Emonet, T.
10.1101/2021.09.29.462473 — neuroscience — Posted on 2021-10-01
4131 The organization of individually mapped structural and functional semantic networks in aging adults
Ketchabaw, W. T.; DeMarco, A. T.; Paul, S.; Dvorak, E.; van der Stelt, C.; Turkeltaub, P. E.
10.1101/2021.09.29.462441 — neuroscience — Posted on 2021-10-01
4133 A deep learning algorithm for potato tuber hollowheart classification
Abbasi, A.; Feldman, M. J.; Park, J.; Greene, K.; Novy, R. G.; Liu, H.
10.1101/2021.09.29.462243 — plant biology — Posted on 2021-10-01
4134 Why can we detect lianas from space?
Visser, M. D.; Detto, M.; Meunier, F.; Wu, J.; Bongalov, B.; Coomes, D.; Nunes, M. H.; Guzman Q., J. A.; Sanchez-Azofeifa, A.; Foster, J.; Broadbent, E.; Verbeeck, H.; Marvin, D.; Chandler, C. J.; van der Heijden, G. M. F.; Boyd, D. S.; Foody, G. M.; Cutler, M. E. J.; Serbin, S.; Schnitzer, S. A.; Rodriguez-Ronderos, M. E.; Pacala, S. W.
10.1101/2021.09.30.462145 — plant biology — Posted on 2021-10-01
4135 AtCGL160 recruits chloroplast coupling factor 1
Reiter, B.; Rosenhammer, L.; Marino, G.; Geimer, S.; Leister, D.; Rühle, T.
10.1101/2021.10.01.462544 — plant biology — Posted on 2021-10-01
4137 Sex Differences in Brain Tumor Glutamine Metabolism Reveal Sex-Specific Vulnerabilities to Treatment
Sponagel, J.; Jones, J. K.; Frankfater, C.; Zhang, S.; Tung, O.; Cho, K.; Tinkum, K. L.; Gass, H.; Nunez, E.; Spitz, D. R.; Chinnaiyan, P.; Schaefer, J.; Patti, G. J.; Graham, M. S.; Mauguen, A.; Grkovski, M.; Dunphy, M. P.; Krebs, S.; Luo, J.; Rubin, J. B.; Ippolito, J. E.
10.1101/2021.09.29.461531 — cancer biology — Posted on 2021-10-01
4138 Computational design of highly signaling active membrane receptors through de novo solvent-mediated allosteric networks
Chen, M.; Lai, J.; Wang, J.; Conners, K.; Russell, A.; Hembre, E.; Rutter, M.; Condon, B.; Kodandapani, L.; Chau, B.; Zhao, X.; Benach, J.; Baker, K.; Barth, P.
10.1101/2021.09.29.462228 — biophysics — Posted on 2021-10-01
4139 A Pre-Processing Pipeline to Quantify, Visualize andReduce Technical Variation in Protein Microarray
Berube, S.; Kobayashi, T.; Wesolowski, A.; Norris, D. E.; Ruczinski, I.; Moss, W. J.; Louis, T. A.
10.1101/2021.09.29.461966 — bioinformatics — Posted on 2021-10-01
4140 SSAM-lite: a light-weight web app for rapid analysis of spatially resolved transcriptomics data
Tiesmeyer, S.; Sahay, S.; Müller-Bötticher, N.; Eils, R.; Mackowiak, S. D.; Ishaque, N.
10.1101/2021.09.29.462194 — bioinformatics — Posted on 2021-10-01
4142 The evolutionary trajectory of drosophilid walking
York, R.; Brezovec, L.; Coughlan, J. M.; Herbst, S.; Krieger, A.; Lee, S.-Y.; Pratt, B.; Smart, A.; Song, E.; Suvorov, A.; Matute, D. R.; Tuthill, J. C.; Clandinin, T.
10.1101/2021.09.29.462444 — animal behavior and cognition — Posted on 2021-10-01
4144 A novel approach to develop wheat chromosome-specific KASP markers for detecting Amblyopyrum muticum segments in doubled haploid introgression lines
Grewal, S.; Coombes, B.; Joynson, R.; Hall, A.; Fellers, J.; Yang, C.-y.; Scholefield, D.; Ashling, S.; Isaac, P.; King, I.; King, J.
10.1101/2021.09.29.462370 — genetics — Posted on 2021-10-01
4147 Experimental evidence for the impact of soil viruses on carbon cycling during surface plant litter decomposition
Albright, M. B.; Gallegos-Graves, L. V.; Feeser, K. L.; Montoya, K.; Emerson, J. B.; Shakya, M.; Dunbar, J.
10.1101/2021.09.29.462240 — ecology — Posted on 2021-10-01
4151 Helminth infection is associated with dampened cytokine responses to viral and bacterial stimulations in Tsimane hunter-horticulturalists.
Schneider-Crease, I.; Blackwell, A. D.; Kraft, T. S.; Emery Thompson, M.; Maldonado Suarez, I.; Cummings, D. K.; Stieglitz, J.; Snyder-Mackler, N.; Gurven, M.; Kaplan, H.; Trumble, B. C.
10.1101/2021.09.29.462428 — immunology — Posted on 2021-10-01
4153 Subcortical Segmentation of the Fetal Brain in 3D Ultrasound using Deep Learning
Hesse, L. S.; Aliasi, M.; Moser, F.; the INTERGROWTH-21st Consortium, ; Haak, M. C.; Xie, W.; Jenkinson, M.; Namburete, A. I.
10.1101/2021.09.29.462430 — neuroscience — Posted on 2021-10-01
4156 Flexible Path Planning through Vicarious Trial and Error
Krichmar, J. L.; Ketz, N. A.; Pilly, P. K.; Soltoggio, A.
10.1101/2021.09.08.459317 — neuroscience — Posted on 2021-10-01
4157 Integrative genomics uncover mechanisms of renal medullary carcinoma transformation, microenvironment landscape and therapeutic vulnerabilities.
Vokshi, B. H.; Davidson, G.; Helleux, A.; Rippinger, M.; Haller, A. R.; Gantzer, J.; Baltzinger, P.; Thouvenin, J.; Bouarich, R.; Manriquez, V.; Zaidi, S.; Msaouel, P.; Su, X.; Lang, H.; Tricard, T.; Lindner, V.; Surdez, D.; Kurtz, J.-E.; Bourdeaut, F.; Tannir, N. M.; Davidson, I.; Malouf, G. G.
10.1101/2021.09.29.462391 — cancer biology — Posted on 2021-10-01
4159 Genome graphs detect human polymorphisms in active epigenomic states during influenza infection
Groza, C.; Chen, X.; Pacis, A.; Simon, M.-M.; Pramatarova, A.; Aracena, K. A.; Pastinen, T.; Barreiro, L. B.; Bourque, G.
10.1101/2021.09.29.462206 — bioinformatics — Posted on 2021-10-01
4161 Reduced motivation for social contact in Disrupted-in-schizophrenia transgenic rats
Seidisarouei, M.; Van Wingerden, M.; Schable, S.; Trossbach, S.; Korth, C.; Kalenscher, T.
10.1101/2021.09.29.462172 — animal behavior and cognition — Posted on 2021-10-01
4165 Supergene formation is associated with a major shift in genome-wide patterns of diversity in a butterfly
Rodriguez de Cara, M. A.; Jay, P.; Chouteau, M.; Whibley, A.; Huber, B.; Piron-Prunier, F.; Ramos, R. R.; Freitas, A. V. L.; Salazar, C.; Silva-Brandao, K. L.; Torres, T. T.; Joron, M.
10.1101/2021.09.29.462348 — evolutionary biology — Posted on 2021-10-01
4167 LOTVS: a global collection of permanent vegetation plots
Sperandii, M. G.; de Bello, F.; Valencia, E.; Goetzenberger, L.; Bazzichetto, M.; Galland, T.; E-Vojtko, A.; Conti, L.; Adler, P.; Buckley, H.; Danihelka, J.; Day, N. J.; Dengler, J.; Eldridge, D. J.; Estiarte, M.; Garcia-Gonzalez, R.; Garnier, E.; Gomez-Garcia, D.; Hallett, L.; Harrison, S. P.; Herben, T.; Ibanez, R.; Jentsch, A.; Juergens, N.; Kertesz, M.; Kimuyu, D. M.; Klumpp, K.; Le Duc, M.; Louault, F.; Marrs, R. H.; Onodi, G.; Pakeman, R. J.; Paertel, M.; Peco, B.; Penuelas, J.; Rueda, M.; Schmidt, W.; Schmiedel, U.; Schuetz, M.; Skalova, H.; Smilauer, P.; Smilauerova, M.; Smit, C.; Son
10.1101/2021.09.29.462383 — ecology — Posted on 2021-10-01
4170 The European Prevention of Alzheimer's Dementia (EPAD) MRI Dataset and Processing Workflow
Lorenzini, L.; Ingala, S.; Wink, A. M.; Kuijer, J.; Wottschel, V.; Dijsselhof, M.; Sudre, C.; Haller, S.; Molinuevo, J. L.; Gispert, J. D.; Cash, D. M.; Thomas, D. L.; Vos, S. B.; Prados, F.; Petr, J.; Wolz, R.; Palombit, A.; Schwarz, A.; Chetelat, G.; Payoux, P.; Di perri, C.; Wardlaw, J.; Frisoni, G. B.; Foley, C.; Fox, N. C.; Ritchie, C.; Pernet, C.; Waldman, A.; Barkhof, F.; Mutsaerts, H. J.
10.1101/2021.09.29.462349 — neuroscience — Posted on 2021-10-01
4174 Modeling spatial, developmental, physiological, and topological constraints on human brain connectivity
Oldham, S.; Fulcher, B. D.; Aquino, K. M.; Arnatkeviciute, A. M.; Paquola, C.; Shishegar, R.; Fornito, A.
10.1101/2021.09.29.462379 — neuroscience — Posted on 2021-10-01
4175 Non-parametric Functional Muscle Network as a Robust Biomarker of Fatigue
O'Keeffe, R.; Shirazi, S. Y.; Yang, J.; Mehrdad, S.; Rao, S.; Atashzar, S. F.
10.1101/2021.09.29.462080 — neuroscience — Posted on 2021-10-01
4176 A preclinical randomized multicenter trial of anti-IL-17A treatment for acute ischemic stroke
Gelderblom, M.; Koch, S.; Strecker, J. K.; Joergensen, C.; Garcia-Bonilla, L.; Ludewig, P.; Bernreuther, C.; Pinnschmidt, H.; Arumugam, T. V.; Thomalla, G.; Faber, C.; Sedlacik, J.; Gerloff, C.; Minnerup, J.; Clausen, B. H.; Anrather, J.; Magnus, T.
10.1101/2021.09.29.462381 — neuroscience — Posted on 2021-10-01
4178 Ex Vivo and In Vivo CD46 Receptor Utilization by Species D Human Adenovirus Serotype 26 (HAdV26)
Hemsath, J. R.; Liaci, M.; Rubin, J.; Parrett, B.; Lu, S.-C.; Nguyen, T.; Turner, M.; Chen, C.; Reddy, V. S.; Cupelli, K.; Stehle, T.; Liszewski, K.; Atkinson, J.; Barry, M. A.
10.1101/2021.09.28.462271 — pharmacology and toxicology — Posted on 2021-10-01
4182 Coral assemblages at higher latitudes favour short-term potential over long-term performance
Cant, J.; Reimer, J. D.; Sommer, B.; Cook, K.; Kim, S. W.; Sims, C. A.; Mezaki, T.; O'Flaherty, C.; Brooks, M.; Malcolm, H. A.; Pandolfi, J. M.; Salguero-Gomez, R.; Beger, M.
10.1101/2021.09.29.462350 — ecology — Posted on 2021-10-01
4183 Identification of fetal liver stromal subsets in spectral cytometry using the parameter autofluorescence
Peixoto, M.; Soares-da-Silva, F.; Schmutz, S.; Mailhe, M.-P.; Novault, S.; Cumano, A.; Ait Mansour, C.
10.1101/2021.09.29.462345 — developmental biology — Posted on 2021-10-01
4184 The kinesin KIF4 mediates HBV/HDV entry through regulation of surface NTCP localization and can be targeted by RXR agonists in vitro.
Gad, S. A.; Sugiyama, M.; Tsuge, M.; Wakae, K.; Fukano, K.; Oshima, M.; Sureau, C.; Watanabe, N.; Kato, T.; Murayama, A.; Li, Y.; Shoji, I.; Shimotohno, K.; Chayama, K.; Muramatsu, M.; Wakita, T.; Nozaki, T.; Aly, H. H.
10.1101/2021.09.29.462331 — microbiology — Posted on 2021-10-01
4185 Comparative Pathogenesis of Different Phylogroup I Bat Lyssaviruses in a Standardized Mouse Model
Klein, A.; Eggerbauer, E.; Potratz, M.; Zaeck, L. M.; Calvelage, S.; Finke, S.; Müller, T.; Freuling, C. M.
10.1101/2021.09.29.462306 — pathology — Posted on 2021-10-01
4187 SPF: A Spatial and Functional Data Analytic Approach to cell Imaging data
Vu, T.; Wrobel, J.; Bitler, B. G.; Schenk, E. L.; Jordan, K. R.; Ghosh, D.
10.1101/2021.09.29.462282 — bioinformatics — Posted on 2021-10-01
4190 Towards a Comprehensive Variation Benchmark for Challenging Medically-Relevant Autosomal Genes
Wagner, J.; Olson, N. D.; Harris, L.; McDaniel, J.; Cheng, H.; Fungtammasan, A.; Hwang, Y.-C.; Gupta, R.; Wenger, A. M.; Rowell, W. J.; Khan, Z. M.; Farek, J.; Zhu, Y.; Pisupati, A.; Mahmoud, M.; Xiao, C.; Yoo, B.; Sahraeian, S. M. E.; Miller, D. E.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Narzisi, G.; Evani, U. S.; Clarke, W. E.; Lee, J.; Mason, C. E.; Lincoln, S. E.; Miga, K. H.; Ebbert, M. T.; Shumate, A.; Li, H.; Chin, C.-S.; Zook, J. M.; Sedlazeck, F. J.
10.1101/2021.06.07.444885 — genomics — Posted on 2021-10-01
4191 Association between Cognitive Function and Large Optic Nerve Cupping, Accounting for Cup-Disc-Ratio Genetic Risk Score
Kravets, S.; Rupnow, R. A.; Sethi, A.; Espeland, M.; Louis, P. R.; Rapp, S.; Klein, B.; Meuer, S.; Haan, M.; Maki, P.; Hallak, J.; Vajaranant, T.
10.1101/2021.09.30.462651 — genetics — Posted on 2021-10-01
4192 Single-cell RNA-seq analysis reveals aberrant CSF1 expression in disease-causing synovial fibroblasts of pigmented villonodular synovitis
Tang, Y.; Ma, M.; Mi, R.; Liu, W.; Hou, J.; Feng, Y.; Zhang, M.; Yu, M.; Li, F.; Song, Y.; Lu, Y.; Yan, Y.; Yang, R.
10.1101/2021.09.29.462128 — molecular biology — Posted on 2021-10-01
4193 In vivo production of pederin by labrenzin pathway expansion
Kacar, D.; Schleissner, C.; Canedo, L.; Rodriguez, P.; de la Calle, F.; Cuevas, C.; Galan, B.; Garcia, J. L.
10.1101/2021.09.29.462382 — molecular biology — Posted on 2021-10-01
4195 Analysis of human brain tissue derived from DBS surgery
Kangas, S. M.; Teppo, J.; Lahtinen, M. J.; Suoranta, A.; Ghimire, B. M.; Mattila, P.; Uusimaa, J.; Varjosalo, M.; Katisko, J.; Hinttala, R.
10.1101/2021.06.18.448926 — neuroscience — Posted on 2021-10-01
4198 TRICLOSAN IS A KCNQ3 POTASSIUM CHANNEL ACTIVATOR
De la Rosa, V.; Guzman-Hernandez, M. L.; Carrillo, E.
10.1101/2021.09.30.462664 — biophysics — Posted on 2021-10-01
4199 Strain and crack propagation of HIV-1 capsids during uncoating
Yu, A.; Lee, E. M. Y.; Briggs, J. A. G.; Ganser-Pornillos, B. K.; Pornillos, O.; Voth, G. A.
10.1101/2021.09.30.462583 — biophysics — Posted on 2021-10-01
4203 Fast and ultra-sensitive glycoform analysis by supercritical fluid chromatography-tandem mass spectrometry
Haga, Y.; Yamada, M.; Fujii, R.; Saichi, N.; Yokokawa, T.; Hama, T.; Hayakawa, Y.; Ueda, K.
10.1101/2021.09.30.462681 — biochemistry — Posted on 2021-10-01
4205 Chromosome-scale and haplotype-resolved genome assembly of a tetraploid potato cultivar
Sun, H.; Jiao, W.-B.; Campoy, J. A.; Krause, K.; Goel, M.; Folz-Donahue, K.; Kukat, C.; Huettel, B.; Schneeberger, K.
10.1101/2021.05.15.444292 — genomics — Posted on 2021-10-01
4207 The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.
Zavala-Alvarado, C.; Garcia Huete, S.; Vincent, A. T.; Sismeiro, O.; Legendre, R.; Varet, H.; Bussotti, G.; Lorioux, C.; Lechat, P.; Coppee, J.-Y.; Veyrier, F. J.; Picardeau, M.; Benaroudj, N.
10.1101/2020.11.06.371039 — microbiology — Posted on 2021-10-01
4208 Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition
Blume, T.; Deussing, M.; Biechele, G.; Peters, F.; Zott, B.; Schmidt, C.; Franzmeier, N.; Wind, K.; Eckenweber, F.; Sacher, C.; Shi, Y.; Ochs, K.; Kleinberger, G.; Xiang, X.; Focke, C.; Lindner, S.; Gildehaus, F.-J.; Beyer, L.; von Ungern-Sternberg, B.; Bartenstein, P.; Baumann, K.; Adelsberger, H.; Rominger, A.; Cumming, P.; Willem, M.; Dorostkar, M. M.; Herms, J.; Brendel, M.
10.1101/2021.05.30.446348 — neuroscience — Posted on 2021-10-01
4209 Surface-based tracking for short association fibre tractography
Shastin, D.; Genc, S.; Parker, G. D.; Koller, K.; Tax, C. M. W.; Evans, J.; Hamandi, K.; Gray, W. P.; Jones, D. K.; Chamberland, M.
10.1101/2021.05.07.443084 — neuroscience — Posted on 2021-10-01
4212 PLETHORA-WOX5 interaction and subnuclear localisation control Arabidopsis root stem cell maintenance
Burkart, R. C.; Strotmann, V. I.; Kirschner, G. K.; Akinci, A.; Czempik, L.; Dolata, A.; Maizel, A.; Weidtkamp-Peters, S.; Stahl, Y.
10.1101/818187 — plant biology — Posted on 2021-10-01
4214 PMCE: efficient inference of expressive models of cancer evolution with high prognostic power
Angaroni, F.; Chen, K.; Damiani, C.; Caravagna, G.; Graudenzi, A.; Ramazzotti, D.
10.1101/008326 — bioinformatics — Posted on 2021-10-01
4215 Identification of blood autosomal cis-expression quantitative trait methylation (cis-eQTMs) in children
Ruiz-Arenas, C.; Hernandez-Ferrer, C.; Vives-Usano, M.; Mari, S.; Quintela, I.; Mason, D.; Cadiou, S.; Casas, M.; Andrusaityte, S.; Gutzkow, K. B.; Vafeiadi, M.; Wright, J.; Lepeule, J.; Grazuleviciene, R.; Chatzi, L.; Carracedo, a.; Estivill, X.; Marti, E.; Escaramis, G.; Vrijheid, M.; Gonzalez, J. R.; Bustamante, M.
10.1101/2020.11.05.368076 — genomics — Posted on 2021-10-01
4220 Cytoskeletal regulation of a transcription factor by DNA mimicry
Haque, F.; Freniere, C.; Ye, Q.; Mani, N.; Wilson-Kubalek, E. M.; Ku, P.-i.; Milligan, R. A.; Subramanian, R.
10.1101/2021.09.30.462597 — cell biology — Posted on 2021-10-01