bioRxiv directory

Harper, L. R.; Lawson Handley, L.; Carpenter, A. I.; Murray-Dickson, G.; Di Muri, C.; Macgregor, C. J.; Logan, T. W.; Law, A.; Breithaupt, T.; Read, D. S.; McDevitt, A.; Hänfling, B.

10.1101/546218 — molecular biology — Posted on 2019-02-28

9 Developmental plasticity in metabolism but not in energy reserve accumulation in a seasonally polyphenic butterfly

Kivelä, S.; Gotthard, K.; Lehmann, P.

10.1101/556969 — evolutionary biology — Posted on 2019-02-28

10 A Pipeline for Fecal Host DNA Analysis by Absolute Quantification of LINE-1 and Mitochondrial Genomic Elements Using ddPCR

He, K.; Fujiwara, H.; Zajac, C.; Sandford, E.; Reddy, P.; Choi, S. W.; Tewari, M.

10.1101/522862 — molecular biology — Posted on 2019-02-28

11 Quantitative investigation of factors relevant to the T cell spot test for tuberculosis infection in active tuberculosis

Li, K.; Yang, C.; Jiang, Z.; Liu, S.; Liu, J.; Fan, C.; Li, T.; Dong, X.

10.1101/561886 — epidemiology — Posted on 2019-02-28

12 MCS^2: Minimal coordinated supports for fast enumeration of minimal cut sets in metabolic networks

Miraskarshahi, R.; Zabeti, H.; Stephen, T.; Chindelevitch, L.

10.1101/471250 — systems biology — Posted on 2019-02-28

13 Predictability changes what we remember in familiar temporal contexts

Kim, H.; Schlichting, M. L.; Preston, A. R.; Lewis-Peacock, J. A.

10.1101/469965 — neuroscience — Posted on 2019-02-28

14 Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins

Ali, I.; Garrido-Ruiz, D.; Ni, Z.; Johnson, J. R.; Zhang, H.; Li, P.-C.; Khalid, M. M.; Conrad, R. J.; Guo, X.; Min, J.; Greenblatt, J.; Jacobson, M.; Krogan, N. J.; Ott, M.

10.1101/442491 — molecular biology — Posted on 2019-02-28

15 Serial horizontal transfer of vitamin-biosynthetic genes enables the establishment of new nutritional symbionts in aphids' di-symbiotic systems

Manzano-Marin, A.; Coeur d'acier, A.; Clamens, A.-L.; Orvain, C.; Cruaud, C.; Barbe, V.; Jousselin, E.

10.1101/556274 — genomics — Posted on 2019-02-28

16 Quantified ensemble 3D surface features modeled as a window on centric diatom valve morphogenesis

Pappas, J. L.

10.1101/468884 — evolutionary biology — Posted on 2019-02-28

17 Thermal sensors improve wrist-worn position tracking

Son, J.; Clucas, J.; White, C.; Krishnakumar, A.; Vogelstein, J.; Milham, M.; Klein, A.

10.1101/552174 — bioinformatics — Posted on 2019-02-28

18 Cholesterol Myth and the Imperative Role of Functional Evaluation of Lipoproteins in Atherosclerotic Risk Prediction Strategies

Ravi, D. B.; Srinivasan, A.; Velusamy, P.; S Narasimhan, K. K.; Chakrapani, L. N.; Singh, A.; Mohan, T.; Thiruvengadam, K.; Moongilpatti Angappa, A.; Periandavan, K.

10.1101/559625 — biochemistry — Posted on 2019-02-28

19 Highly efficient homology-directed repair using transient CRISPR/Cpf1-geminiviral replicon in tomato

Vu, T. V.; Sivankalyani, V.; Kim, E.-J.; Tran, M. T.; Kim, J.; Sung, Y. W.; Doan, D. T. H.; Kim, J.-Y.

10.1101/521419 — molecular biology — Posted on 2019-02-28

20 Molecular dating of the emergence of anaerobic rumen fungi and the impact of laterally acquired genes

Wang, Y.; Youssef, N.; Couger, M.; Hanafy, R.; Elshahed, M.; Stajich, J. E.

10.1101/401869 — evolutionary biology — Posted on 2019-02-28

21 Flavor-Cyber-Agriculture: Optimization of plant metabolites in an open-source control environment through surrogate modeling

Johnson, A. J.; Meyerson, E.; de la Parra, J.; Savas, T. L.; Miikkulainen, R.; Harper, C. B.

10.1101/424226 — plant biology — Posted on 2019-02-28

22 Hidden Rice Diversity in the Guianas

van Andel, T.; Veltman, M.; Bertin, A.; Maat, H.; Polime, T.; Hille Ris Lambers, D.; Tjoe Awie, J.; De Boer, H. J.; Manzanilla, V.

10.1101/562769 — plant biology — Posted on 2019-02-28

23 Differential effects of diet and weight on taste responses in diet-induced obese mice

Ahart, Z. C.; Martin, L. E.; Kemp, B. R.; Dutta Banik, D.; Roberts, S. G. E.; Torregrossa, A. M.; Medler, K.

10.1101/564211 — neuroscience — Posted on 2019-02-28

24 Transcranial Alternating Current Stimulation (tACS) Entrains Alpha Oscillations by Preferential Phase Synchronization of Fast-Spiking Cortical Neurons to Stimulation Waveform

Negahbani, E.; Stitt, I. M.; Davey, M.; Doan, T. T.; Dannhauer, M.; Hoover, A. C.; Peterchev, A. V.; Radtke-Schuller, S.; Fröhlich, F.

10.1101/563163 — neuroscience — Posted on 2019-02-28

25 Time-Invariant Working Memory Representations in the Presence of Code-Morphing in the Lateral Prefrontal Cortex

Parthasarathy, A.; Tang, C.; Herikstad, R.; Cheong, L. F.; Yen, S.-C.; Libedinsky, C.

10.1101/563668 — neuroscience — Posted on 2019-02-28

26 Definitely saw it coming? An ERP study on the role of article gender and definiteness in predictive processing

Fleur, D.; Flecken, M.; Rommers, J.; Nieuwland, M.

10.1101/563783 — neuroscience — Posted on 2019-02-28

27 Do direct nose-to-brain pathways underlie intranasal oxytocin-induced changes in regional cerebral blood flow in humans?

Martins, D.; Mazibuko, N.; Zelaya, F.; Vasilakopoulou, S.; Loveridge, J.; Oates, A.; Maltezos, S.; Mehta, M.; Howard, M.; McAlonan, G.; Murphy, D.; Williams, S.; Fotopoulou, A.; Schuschnig, U.; Paloyelis, Y.

10.1101/563056 — neuroscience — Posted on 2019-02-28

28 Occurrence of Cryptosporidium hominis in cattle bordering the Lake Mburo National Park in Kiruhura district, Western Uganda

Witto, S. G.; Kankya, C.; Kazibwe, A. J.; Akurut, G.; Ochwo, S.

10.1101/562793 — microbiology — Posted on 2019-02-28

29 Effect of environment on the evolutionary trajectories and growth characteristics of antibiotic- resistant Escherichia coli mutants

Hubbard, A. T.; Jafari, N. V.; Feasey, N. A.; Rohn, J. L.; Roberts, A. P.

10.1101/262691 — microbiology — Posted on 2019-02-28

30 Recovering signals of ghost archaic introgression in African populations

Durvasula, A.; Sankararaman, S.

10.1101/285734 — genomics — Posted on 2019-02-28

31 Allele frequency distribution of SNPs associated with levels of Vitamin D-binding protein and 25-hydroxyvitamin D

Nizamutdinov, I.; Popov, I.; Ilinsky, V.; Rakitko, A.

10.1101/564229 — genetics — Posted on 2019-02-28

32 Repeatability of adaptive radiation depends on spatial scale: regional versus global replicates of stickleback in lake versus stream habitats

Paccard, A.; Hanson, D.; Stuart, Y. E.; von Hippel, F. A.; Kalbe, M.; Klepaker, T.; Skulason, S.; Kristjansson, B. K.; Bolnick, D. I.; Hendry, A. P.; Barrett, R. D.

10.1101/564005 — evolutionary biology — Posted on 2019-02-28

33 Assessing connectivity despite high diversity in island populations of a malaria mosquito

Bergey, C. M.; Lukindu, M.; Wiltshire, R. M.; Fontaine, M. C.; Kayondo, J. K.; Besansky, N. J.

10.1101/430702 — evolutionary biology — Posted on 2019-02-28

34 Comment on 'Valid molecular dynamics simulations of human hemoglobin require a surprisingly large box size'

Gapsys, V.; de Groot, B. L.

10.1101/563064 — biophysics — Posted on 2019-02-28

35 Self-assembly of polymer-encased lipid nanodiscs and membrane protein reconstitution

Sahoo, B.; Genjo, T.; Maharana, K.; Ramamoorthy, A.

10.1101/476556 — biophysics — Posted on 2019-02-28

36 Growth-coupled overproduction is theoretically possiblefor most metabolites even in Saccharomyces cerevisiae under anaerobic condition

Tamura, T.

10.1101/563437 — bioinformatics — Posted on 2019-02-28

37 Monarch butterfly declines reported in Boyle et al. (2019) are biased by unexamined changes in museum collections over time

Wepprich, T. M.

10.1101/562314 — ecology — Posted on 2019-02-28

38 A conserved requirement for Fbxo7 during male germ cell cytoplasmic remodelling

Rathje, C. C.; Randle, S. J.; Al Rawi, S.; Skinner, B. M.; Johnson, E. E.; Bacon, J.; Vlazaki, M.; Affara, N. A.; Ellis, P. J.; Laman, H.

10.1101/563718 — developmental biology — Posted on 2019-02-28

39 Harnessing patient-specific response dynamics to optimize evolutionary therapies for metastatic clear cell renal cell carcinoma - Learning to adapt

Sorribes, I. C.; Basu, A.; Brady, R.; Enriquez-Navas, P. M.; Feng, X.; Kather, J. N.; Nerlakanti, N.; Stephens, R.; Strobl, M.; Tavassoly, I.; Vitos, N.; Lemanne, D.; Manley, B.; O'Farrelly, C.; Enderling, H.

10.1101/563130 — cancer biology — Posted on 2019-02-28

40 The FluPRINT dataset: A multidimensional analysis of the influenza vaccine imprint on the immune system

Tomic, A.; Tomic, I.; Dekker, C. L.; Maecker, H. T.; Davis, M. M.

10.1101/564062 — systems biology — Posted on 2019-02-28

41 Human-level recognition of blast cells in acute myeloid leukemia with convolutional neural networks

Matek, C.; Schwarz, S.; Spiekermann, K.; Marr, C.

10.1101/564039 — pathology — Posted on 2019-02-28

42 Theta phase synchrony is sensitive to corollary discharge abnormalities in early illness schizophrenia but not in the clinical high-risk syndrome

Ford, J. M.; Roach, B. J.; Loewy, R.; Stuart, B.; Mathalon, D. H.

10.1101/563460 — neuroscience — Posted on 2019-02-28

43 μECoG Recordings Through a Thinned Skull

Brodnick, S. K.; Ness, J.; Richner, T.; Thongpang, S.; Novello, J.; Hayat, M.; Cheng, K. P.; Krugner-Higby, L.; Suminski, A. J.; Ludwig, K.; Williams, J. C.

10.1101/564146 — neuroscience — Posted on 2019-02-28

44 The complexity dividend: when sophisticated inference matters

Tavoni, G.; Balasubramanian, V.; Gold, J. I.

10.1101/563346 — neuroscience — Posted on 2019-02-28

45 Joint modelling of diffusion MRI and microscopy

Howard, A. F.; Mollink, J.; Kleinnijenhuis, M.; Pallebage-Gamarallage, M.; Bastiani, M.; Cottaar, M.; Miller, K. L.; Jbabdi, S.

10.1101/563809 — neuroscience — Posted on 2019-02-28

46 Isolating the key factors defining the magnitude of hippocampal neurogenesis' effects on anxiety, memory and pattern separation

Franca, T. F. A.

10.1101/563023 — neuroscience — Posted on 2019-02-28

47 GCIB-SEM: A path to 10 nm isotropic imaging of cubic millimeter volumes

Hayworth, K. J.; Peale, D.; Januszewski, M.; Knott, G.; Lu, Z.; Xu, C. S.; Hess, H. F.

10.1101/563239 — neuroscience — Posted on 2019-02-28

48 The laminar profile of sleep spindles in humans

Ujma, P. P.; Hajnal, B.; Bodizs, R.; Gombos, F.; Eross, L.; Wittner, L.; Halgren, E.; Cash, S.; Ulbert, I.; Fabo, D.

10.1101/563221 — neuroscience — Posted on 2019-02-28

49 Ticks Home in on Body Heat: A New Understanding of Ectoparasite Host-Seeking and Repellent Action

Carr, A. L.; Salgado, V.

10.1101/564179 — neuroscience — Posted on 2019-02-28

50 Gene expression noise produces cell-to-cell heterogeneity in eukaryotic homologous recombination rate

Liu, J.; Francois, J.-M.; Capp, J.-P.

10.1101/563643 — molecular biology — Posted on 2019-02-28

51 Environmental plasticity and colonisation history in the Atlantic salmon microbiome: a translocation experiment

Uren Webster, T.; Rodriguez Barreto, D.; Castaldo, G.; Taylor, J.; Gough, P.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/564104 — microbiology — Posted on 2019-02-28

52 Alanine Metabolism in Bacillus subtilis

Sidiq, K. R.; Chow, M.; Zhao, Z.; Daniel, R.

10.1101/562850 — microbiology — Posted on 2019-02-28

53 Improving diagnosis and monitoring of treatment response in pulmonary tuberculosis using the molecular bacterial load assay (MBLA)

Sabiiti, W.; Azam, K.; Kuchaka, D.; Mtafya, B.; Bowness, R. E.; Oravcova, K.; Farmer, E.; Honeyborne, I.; Evangelopoulos, D.; McHugh, T. D.; Xiao, H.; Khosa, C.; Rachow, A.; Heinrich, N.; Kampira, E.; Davies, G.; Bhatt, N.; Ntinginya, N.; Viegas, S.; Jani, I.; Kamdolozi, M.; Mdolo, a.; Khonga, M.; Boeree, M. J.; Philips, P. P.; Sloan, D. J.; Hoelscher, M.; Kibiki, G.; Gillespie, S. H.

10.1101/555995 — microbiology — Posted on 2019-02-28

54 Parasite histones mediate leak and coagulopathy in cerebral malaria

Moxon, C. A.; Alhamdi, Y.; Storm, J.; Toh, J.; Ko, J. Y.; Murphy, G.; Taylor, T.; Seydel, K.; Kampondeni, S.; Potchen, M.; O'Donnell, J.; O'Regan, N.; Wang, G.; Garcia-Cardena, G.; Molyneux, M.; Craig, A.; Abrams, S.; Toh, C.-H.

10.1101/563551 — microbiology — Posted on 2019-02-28

55 Antibiotic killing of diversely generated populations of non-replicating bacteria

McCall, I. C.; Shah, N.; Govindan, A.; Baquero, F.; Levin, B. R.

10.1101/464628 — microbiology — Posted on 2019-02-28

56 Combining amoxicillin and relebactam provides new therapeutic potential for Mycobacterium abscessus infection

Lopeman, R. C.; Harrison, J.; Desai, M.; Lambert, P. A.; Cox, J. A. G.

10.1101/563189 — microbiology — Posted on 2019-02-28

57 Dissection of the Hydrogen Metabolism of the Enterobacterium Trabulsiella guamensis: Identification of a Formate-Dependent and Essential Formate Hydrogenlyase Complex Exhibiting Phylogenetic Similarity to Complex I.

Lindenstrauss, U.; Pinske, C.

10.1101/563510 — microbiology — Posted on 2019-02-28

58 Elucidating syntrophic butyrate-degrading populations in anaerobic digesters using stable isotope-informed genome-resolved metagenomics

Ziels, R. M.; Nobu, M. K.; Sousa, D. Z.

10.1101/563387 — microbiology — Posted on 2019-02-28

59 Effects of topical PaiTeLing in nude mice implanted with human condyloma acuminatum tissue infected with HPV 6, 31, and 81: comparison with imiquimod and interferon-α-2b

Xu, R.; Wang, L.; Hou, J.; Li, J.; Fan, Z.; Wu, L.; Zhu, C.; Ma, M.; Wang, H.; Hou, S.

10.1101/563536 — immunology — Posted on 2019-02-28

60 Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Rodriques, S. G.; Stickels, R. R.; Goeva, A.; Martin, C. A.; Murray, E.; Vanderburg, C. R.; Welch, J.; Chen, L. M.; Chen, F.; Macosko, E. Z.

10.1101/563395 — genomics — Posted on 2019-02-28

61 An Integrated Framework for Genome Analysis Reveals Numerous Previously Unrecognizable Structural Variants in Leukemia Patients' Samples

Xu, J.; Song, F.; Schleicher, E.; Pool, C.; Bann, D.; Hennessy, M.; Sheldon, K.; Batchelder, E.; Annageldiyev, C.; Sharma, A.; Chang, Y.; Hastie, A.; Miller, B.; Goldenberg, D.; Mineishi, S.; Claxton, D.; Moldovan, G.-L.; Yue, F.; Broach, J. R.

10.1101/563270 — genomics — Posted on 2019-02-28

62 Dietary restriction induces post-transcriptional regulation of longevity genes.

Rollins, J. A.; Snow, S.; Kapahi, P.; Rogers, A. N.

10.1101/563296 — genomics — Posted on 2019-02-28

63 A Multiplex Pharmacogenetics Assay using the MinION Nanopore Sequencing Device

Liau, Y.; Cree, S. L.; Maggo, S.; Miller, A. L.; Pearson, J. F.; Gladding, P. A.; Kennedy, M. A.

10.1101/563262 — genetics — Posted on 2019-02-28

64 Genomic footprints of local adaptation along elevation gradients associate with present phenotypic variation in teosintes

Fustier, M.-A.; Martinez-Ainsworth, N. E.; Venon, A.; Corti, H.; Rousselet, A.; Dumas, F.; Dittberner, H.; Aguirre-Liguori, J.; Camarena, M. G.; Grimanelli, D.; Falque, M.; Moreau, L.; de Meaux, J.; Montes-Hernandez, S.; Eguiarte, L. E.; Vigouroux, Y.; Manicacci, D.; Tenaillon, M. I.

10.1101/563585 — evolutionary biology — Posted on 2019-02-28

65 Evaluating the within-host dynamics of Ranavirus infection with mechanistic disease models and experimental data

Mihaljevic, J. R.; Greer, A. L.; Brunner, J. L.

10.1101/564120 — ecology — Posted on 2019-02-28

66 Islands in the desert: Environmental distribution modelling of endemic flora reveals the extent of Pleistocene tropical relict vegetation in southern Arabia

Borrell, J. S.; Al Issaey, G.; Lupton, D. A.; Starnes, T.; Al Hinai, A.; Al Hatmi, S.; Senior, R. A.; Wilkinson, T.; Milborrow, J. L. H.; Stokes-Rees, A.; Patzelt, A.

10.1101/563650 — ecology — Posted on 2019-02-28

67 Challenges and opportunities in population monitoring of cheetahs

Linden, D. W.; Green, D. S.; Chelysheva, E. V.; Mandela, S.; Dloniak, S. M.

10.1101/563122 — ecology — Posted on 2019-02-28

68 Comments on the recent crystal structure of TsaBDE complex of bacterial t6A biosynthesis system and its significance for understanding TC-AMP processing.

Stec, B.

10.1101/563171 — biophysics — Posted on 2019-02-28

69 Keratin-Based Epidermal Green Autofluorescence is a Common Biomarker of Organ Injury

Zhang, M.; Li, Y.; Maharjan, D. T.; He, H.; Tao, Y.; Wu, D.; Ying, W.

10.1101/564112 — biophysics — Posted on 2019-02-28

70 Applying Citizen Science to Gene, Drug, Disease Relationship Extraction from Biomedical Abstracts.

Tsueng, G.; Nanis, M.; Fouquier, J.; Mayers, M.; Good, B.; Su, A. I.

10.1101/564187 — bioinformatics — Posted on 2019-02-28

71 Likelihood-free nested sampling for biochemical reaction networks

Mikelson, J.; Khammash, M.

10.1101/564047 — bioinformatics — Posted on 2019-02-28

72 Deep learning in bioinformatics: introduction, application, and perspective in big data era

Li, Y.; Huang, C.; Ding, L.; Li, Z.; Pan, Y.; Gao, X.

10.1101/563601 — bioinformatics — Posted on 2019-02-28

73 Synthetic Promoter Design in Escherichia coli based on Generative Adversarial Network

Wang, Y.; Wang, H.; Liu, L.; Wang, X.

10.1101/563775 — bioinformatics — Posted on 2019-02-28

74 Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of class C G protein-coupled receptors

Acosta-Ruiz, A.; Gutzeit, V. A.; Skelly, M. J.; Meadows, S.; Lee, J.; Orr, A. G.; Pleil, K.; Broichhagen, J.; Levitz, J.

10.1101/563957 — bioengineering — Posted on 2019-02-28

75 Solid state anaerobic digestion of mixed organic waste: the synergistic effect of food waste addition on the destruction of paper and cardboard

Guilford, N. G. H.; Lee, H. P.; Kanger, K.; Meyer, T.; Edwards, E. A.

10.1101/564203 — bioengineering — Posted on 2019-02-28

76 Human lung organoids develop into adult airway-like structures directed by physico-chemical biomaterial properties

Dye, B. R.; Youngblood, R. L.; Oakes, R. S.; Kasputis, T.; Clough, D. W.; Nagy, M. S.; Spence, J. R.; Shea, L. D.

10.1101/564252 — bioengineering — Posted on 2019-02-28

77 Biodiversity lost: The phylogenetic relationships of a complete mitochondrial DNA genome sequenced from the extinct wolf population of Sicily

Reale, S.; Randi, E.; Bonanno, F.; Cumbo, V.; Sammarco, I.; Spinnato, A.; Seminara, S.

10.1101/563684 — zoology — Posted on 2019-02-28

78 Pharmacokinetics Modeling and Simulation of Voriconazole Dosing and Safety in Patients with Liver Cirrhosis

Wang, T.; Yan, M.; Tang, D.; Dong, Y.; Zhu, L.; Du, Q.; Sun, D.; Xing, J.; Dong, Y.

10.1101/563528 — pharmacology and toxicology — Posted on 2019-02-28

79 Transient perturbation of the left temporal cortex evokes plasticity-related reconfiguration of the lexical network

Klaus, J.; Schutter, D. J. L. G.; Piai, V.

10.1101/562827 — neuroscience — Posted on 2019-02-28

80 In-depth genetic analysis of 6p21.3 reveals insights into associations between HLA types and complex traits and disease

D'Antonio, M.; Reyna, J.; D'Antonio-Chronowska, A.; Bonder, M.-J.; Jakubosky, D.; Matsui, H.; Smith, E. N.; Stegle, O.; Nariai, N.; Frazer, K. A.

10.1101/564161 — genomics — Posted on 2019-02-28

81 A unicellular relative of animals generates an epithelium-like cell layer by actomyosin-dependent cellularization

Dudin, O.; Ondracka, A.; Grau-Bove, X.; A.B. Haraldsen, A.; Toyoda, A.; Suga, H.; Brate, J.; Ruiz-Trillo, I.

10.1101/563726 — evolutionary biology — Posted on 2019-02-28

82 Ecological strategy and genetic load in the shepherd's purse (Capsella bursa-pastoris) from the core and the limit of its natural range.

Orsucci, M.; Milesi, P.; Hansen, J.; Girodolle, J.; Glemin, S.; Lascoux, M.

10.1101/563569 — evolutionary biology — Posted on 2019-02-28

83 How important is it to consider lineage diversification heterogeneity in macroevolutionary studies: lessons from the lizard family Liolaemidae

Olave, M.; Avila, L. J.; Sites, J. W.; Morando, M.

10.1101/563635 — evolutionary biology — Posted on 2019-02-28

84 Hypothesis, analysis and synthesis: it's all Greek to me!

Iliopoulos, I.; Ananiadou, S.; Danchin, A.; Ioannidis, J. P.; Katsikis, P. D.; Ouzounis, C. A.; Promponas, V. J.

10.1101/561175 — scientific communication and education — Posted on 2019-02-28

85 What Drives Symbiotic Calcium Signalling In Legumes? Insights And Challenges Of Imaging

Vaz Martins, T.; Livina, V. N.

10.1101/559971 — plant biology — Posted on 2019-02-28

86 High-throughput targeted gene deletion in the model mushroom Schizophyllum commune using pre-assembled Cas9 ribonucleoproteins

Vonk, P. J.; Escobar, N.; Wosten, H. A. B.; Lugones, L. G.; Ohm, R. A.

10.1101/563759 — microbiology — Posted on 2019-02-28

87 Identification of new MmpL3 inhibitors by untargeted and targeted mutant screens defines MmpL3 domains with differential resistance

Williams, J. T.; Haiderer, E. R.; Coulson, G. B.; Conner, K. N.; Ellsworth, E.; Chen, C.; Dick, T.; Abramovitch, R. B.

10.1101/564245 — microbiology — Posted on 2019-02-28

88 Multi-site sampling and risk prioritization reveals the public health relevance of antibiotic resistance genes found in wastewater environments

Dai, C.; Duvallet, C.; Zhang, A. N.; Matus, M. G.; Ghaeli, N.; Park, S.; Endo, N.; Isazadeh, S.; Jamil, K.; Ratti, C.; Alm, E. J.

10.1101/562496 — microbiology — Posted on 2019-02-28

89 Development of a Comprehensive Antibody Staining Database using a Standardized Analytics Pipeline

Amir, E.-a. D.; Lee, B.; Badoual, P.; Gordon, M.; Guo, X. V.; Merad, M.; Rahman, A. H.

10.1101/563742 — immunology — Posted on 2019-02-28

90 CTCF confers local nucleosome resiliency after DNA replication and during mitosis

Owens, N.; Papadopoulou, T.; Festuccia, N.; Tachtsidi, A.; Gonzalez, I.; Dubois, A.; Vandormael-Pournin, S.; Nora, E. P.; Bruneau, B. G.; Cohen-Tannoudji, M.; Navarro, P.

10.1101/563619 — genomics — Posted on 2019-02-28

91 A meta-analysis on the benefits and costs of hosting secondary endosymbionts in sap-sucking insects

Zytynska, S. E.; Thighiouart, K.; Frago, E.

10.1101/563031 — ecology — Posted on 2019-02-28

92 Higher-order interaction inhibits bacterial invasion of a phototroph-predator microbial community

Mickalide, H.; Kuehn, S.

10.1101/564260 — ecology — Posted on 2019-02-28

93 scds: Computational Annotation of Doublets in Single Cell RNA Sequencing Data

Bais, A. S.; Kostka, D.

10.1101/564021 — bioinformatics — Posted on 2019-02-28

94 Artificial Intelligence for Bioinformatics: Applications in Protein Folding Prediction

Staples, M.; Chan, L.; Si, D.; Johnson, K.; Whyte, C.; Cao, R.

10.1101/561027 — bioinformatics — Posted on 2019-02-28

95 TraitCorr - correlating gene expression measurements with phenotypic data

Nussbaumer, T.; Wagner, C.; Heidari, P.

10.1101/557975 — bioinformatics — Posted on 2019-02-28

96 Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

Wang, Z.; Chen, H.; Bartz, T. M.; Bielak, L. F.; Chasman, D. I.; Feitosa, M. F.; Franceschini, N.; Guo, X.; Lim, E.; Noordam, R.; Richard, M. A.; Wang, H.; Cade, B.; Adrienne Cupples, L.; de Vries, P. S.; Giulanini, F.; Lee, J.; Lemaitre, R. N.; Martin, L. W.; Reiner, A. P.; Rich, S. S.; Schreiner, P. J.; Sidney, S.; Sitlani, C. M.; Smith, J. A.; Willems van Dijk, K.; Yao, J.; Zhao, W.; Fornage, M.; Kardia, S. L. R.; Kooperberg, C.; Liu, C.-T.; Mook-Kanamori, D. O.; Province, M. A.; Psaty, B. M.; Redline, S.; Ridker, P. M.; Rotter, J. I.; Boerwinkle, E.; Morrison, A. C.; the CHARGE Gene-Lifest

10.1101/561225 — epidemiology — Posted on 2019-02-28

97 Spatial distribution and spread potential of sixteen Leptospira serovars in a subtropical region of Brazil

Jara, M.; Escobar, L.; Rodriges, R. O.; Frias, A.; Sanhueza, J.; Machado, G.

10.1101/559609 — epidemiology — Posted on 2019-02-28

98 Predicting vaccine effectiveness in livestock populations: a theoretical framework applied to PRRS virus infections in pigs

Bitsouni, V.; Lycett, S.; Opriessnig, T.; Doeschl-Wilson, A.

10.1101/563205 — epidemiology — Posted on 2019-02-28

99 Adverse perinatal outcomes for obese women are influenced by the presence of comorbid diabetes and hypertensive disorders

Aubry, E. M.; Oelhafen, S.; Fankhauser, N.; Raio, L.; Cignacco, E. L.

10.1101/559856 — epidemiology — Posted on 2019-02-28

100 EMULSION: transparent and flexible multiscale stochastic models in epidemiology

Picault, S.; Huang, Y.-L.; Sicard, V.; Arnoux, S.; Beaunee, G.; Ezanno, P.

10.1101/563791 — epidemiology — Posted on 2019-02-28

101 Early Prediction of Antigenic Transitions for Influenza A H3N2

Castro, L.; Bedford, T.; Meyers, L.

10.1101/558577 — epidemiology — Posted on 2019-02-28

102 Distinct YFV lineages co-circulated in the Central-Western and Southeastern Brazilian regions from 2015 to 2018

Delatorre, E.; de Abreu, F. V. S.; Ribeiro, I. P.; Gomez, M. M.; dos Santos, A. A. C.; Ferreira-de-Brito, A.; Neves, M. S. A. S.; Bonelly, I.; de Miranda, R. M.; Furtado, N. D.; Raphael, L. M. S.; da Silva, L. d. F. F.; de Castro, M. G.; Ramos, D. G.; Romano, A. P. M.; Kallas, E. G.; Vicente, A. C. P.; Bello, G.; Lourenco-de-Oliveira, R.; Bonaldo, M. C.

10.1101/560714 — epidemiology — Posted on 2019-02-28

103 Optimised prophylactic vaccination in metapopulations

Teo, M.; Bean, N.; Ross, J.

10.1101/559732 — epidemiology — Posted on 2019-02-28

104 Association the 25(OH) vitamin D status with Upper Respiratory Tract Infections Morbidity in Water Sports Elite Athletes

Umarov, J.; Kerimov, F.; Toychiev, A.; Davis, N.; Osipova, S.

10.1101/559278 — epidemiology — Posted on 2019-02-28

105 A knowledge-based scoring function to assess the stability of quaternary protein assemblies

Dhawanjewar, A. S.; Roy, A. A.; Madhusudhan, M. S.

10.1101/562520 — bioinformatics — Posted on 2019-02-28

106 Phylogenetically based establishment of a dengue virus panel, representing all available genotypes, as a tool in dengue drug discovery

Touret, F.; Baronti, C.; Goethals, O.; Van Loock, M.; De Lamballerie, X.; Querat, G.

10.1101/439695 — microbiology — Posted on 2019-02-28

107 Divergence in gut microbial communities mirrors a social group fission event in a black-and-white colobus monkey (Colobus vellerosus)

Goodfellow, C.; Whitney, T.; Christie, D.; Sicotte, P.; Wikberg, E.; Ting, N.

10.1101/511618 — ecology — Posted on 2019-02-28

108 A spatial cell culture model for predicting chemotherapy dosing strategies

Zhu, S.; Deb, D.; Danino, T.

10.1101/561746 — cancer biology — Posted on 2019-02-28

109 Stochastic gene expression influences the selection of antibiotic resistance mutations

Sun, L.; Ashcroft, P.; Ackermann, M.; Bonhoeffer, S.

10.1101/563015 — evolutionary biology — Posted on 2019-02-28

110 Heart development in the lizards (Varanidae) with the greatest extent of ventricular septation

Hanemaaijer, J.; Gregorovicova, M.; Nielsen, J.; Moorman, A.; Wang, T.; Planken, R. N.; Christoffels, V.; Sedmera, D.; Jensen, B.

10.1101/563767 — evolutionary biology — Posted on 2019-02-28

111 Molecular architecture of a membrane-spanning hormone acyltransferase required for metabolic regulation

Campana, M. B.; Irudayanathan, F. J.; Davis, T. R.; McGovern-Gooch, K. R.; Loftus, R.; Ashkar, M.; Escoffery, N.; Navarro, M.; Sieburg, M. A.; nangia, S.; Hougland, J. L.

10.1101/556233 — biochemistry — Posted on 2019-02-28

112 A geometric representation unveils rule-learning dynamics in primate neurons

Cohen, Y.; Schneidman, E.; Paz, R.

10.1101/561670 — neuroscience — Posted on 2019-02-28

113 High-density spatial transcriptomics arrays for in situ tissue profiling

Vickovic, S.; Eraslan, G.; Klughammer, J.; Stenbeck, L.; Salmen, F.; Aijo, T.; Bonneau, R.; Bergenstraahle, L.; Gould, J.; Ronaghi, M.; Frisen, J.; Lundeberg, J.; Regev, A.; Staahl, P. L.

10.1101/563338 — genomics — Posted on 2019-02-28

114 Genome-wide Interaction Studies by the CHARGE Gene-Lifestyle Interactions Working Group: what we have learned and what is coming next.

Laville, V.; Majarian, T.; Sung, Y. J.; Feitosa, M. F.; Chasman, D.; Bentley, A. R.; Rotimi, C. N.; Cupples, A. L.; de Vries, P. S.; Brown, M. R.; Morrison, A. C.; Kraja, A. T.; Province, M.; Schwander, K.; Gauderman, J.; Rao, D.; Manning, A.; Aschard, H.

10.1101/562157 — genetics — Posted on 2019-02-28

115 Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of a transcription factor

Escobedo, A.; Topal, B.; Kunze, M. B. A.; Aranda, J.; Chiesa, G.; Mungianu, D.; Bernardo-Seisedos, G.; Eftekharzadeh, B.; Gairi, M.; Pieratelli, R.; Felli, I.; Diercks, T.; Millet, O.; Garcia, J.; Orozco, M.; Crehuet, R.; Lindorff-Larsen, K.; Salvatella, X.

10.1101/447896 — biophysics — Posted on 2019-02-28

116 High-coverage, long-read sequencing of Han Chinese trio reference samples.

Wang, Y.-C.; Olson, N. D.; Deikus, G.; Shah, H.; Wenger, A. M.; Trow, J.; Xiao, C.; Sherry, S.; Salit, M. L.; Zook, J. M.; Smith, M.; Sebra, R.

10.1101/562611 — genomics — Posted on 2019-02-28

117 Antimicrobial resistance prevalence, rates of hospitalization with septicemia and rates of mortality with sepsis in adults in different US states

Goldstein, E.; MacFadden, D. R.; Karaca, Z.; Steiner, C. A.; Viboud, C.; Lipsitch, M.

10.1101/404137 — epidemiology — Posted on 2019-02-28

118 Toward perfect reads: short reads correction via mapping on compacted de Bruijn graphs

Limasset, A.; Flot, J.-F.; Peterlongo, P.

10.1101/558395 — bioinformatics — Posted on 2019-02-28

119 Evaluation of methods to assign cell type labels to cell clusters from single-cell RNA-sequencing data

Diaz-Mejia, J. J.; Meng, E. C.; Pico, A. R.; MacParland, S. A.; Ketela, T.; Pugh, T. J.; Bader, G. D.; Morris, J. H.

10.1101/562082 — bioinformatics — Posted on 2019-02-28

120 Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism

Fox, N. G.; Yu, X.; Feng, X.; Bailey, H. J.; Martelli, A.; Nabhan, J. F.; Strain-Damerell, C.; Bulawa, C.; Yue, W. W.; Han, S.

10.1101/561795 — biochemistry — Posted on 2019-02-28

121 A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

Richardson, T. G.; Hemani, G.; Gaunt, T. R.; Relton, C. L.; Davey Smith, G.

10.1101/563379 — genetics — Posted on 2019-02-28

122 Combinations of Spok genes create multiple meiotic drivers in Podospora

Vogan, A. A.; Ament-Velasquez, S. L.; Granger-Farbos, A.; Svedberg, J.; Bastiaans, E.; Debets, A. J. M.; Coustou, V.; Yvanne, H.; Clave, C.; Saupe, S. J.; Johannesson, H.

10.1101/562892 — genetics — Posted on 2019-02-28

123 Patterns, Profiles, and Parsimony: dissecting transcriptional signatures from minimal single-cell RNA-seq output with SALSA

Lozoya, O. A.; McClelland, K. S. S.; Papas, B.; Li, J.-L.; Woychik, R. P.; Yao, H. H.-C.

10.1101/551762 — bioinformatics — Posted on 2019-02-28

124 Explicit Neural Models for Flip-Flops and Oscillators Generate Phenomena of Short-Term Memory and Electroencephalography

Yoder, L.

10.1101/403196 — neuroscience — Posted on 2019-02-28

125 An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice

Eyer, L.; Nougairede, A.; Uhlirova, M.; Driouich, J.-S.; Zouharova, D.; Valdes, J. J.; Haviernik, J.; Gould, E. A.; De Clercq, E.; de Lamballerie, X.; Ruzek, D.

10.1101/563544 — microbiology — Posted on 2019-02-28

126 Impact of permagarden intervention on improving fruit and vegetable intake among vulnerable groups. A quasi-experimental study conducted in seven cities of Ethiopia

Alemu, F. M.; Mecha, M.; Medhin, G.

10.1101/563965 — epidemiology — Posted on 2019-02-28

127 Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic

Cholewa-Waclaw, J.; Shah, R.; Webb, S.; Chhatbar, K.; Ramsahoye, B.; Pusch, O.; Yu, M.; Greulich, P.; Waclaw, B.; Bird, A.

10.1101/391904 — biophysics — Posted on 2019-02-28

128 Segmentation of Glomeruli Within Trichrome Images Using Deep Learning

Kannan, S.; Morgan, L. A.; Liang, B.; Cheung, M.; Lin, C. Q.; Mun, D.; Nader, R. G.; Belghasem, M. E.; Henderson, J. M.; Francis, J. M.; Chitalia, V. C.; Kolachalama, V. B.

10.1101/345579 — pathology — Posted on 2019-02-28

129 On the impact of the pangenome and annotation discrepancies while building protein sequence databases for bacteria proteogenomics

Machado, K. C.; Fortuin, S.; Tomazella, G. G.; Fonseca, A. F.; Warren, R.; Wiker, H. G.; de Souza, S. J.; de Souza, G. A.

10.1101/378117 — bioinformatics — Posted on 2019-02-28

130 Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning

Najafi, F.; Elsayed, G. F.; Cao, R.; Pnevmatikakis, E.; Latham, P. E.; Cunningham, J.; Churchland, A. K.

10.1101/354340 — neuroscience — Posted on 2019-02-28

131 A distributed neural code in the dentate gyrus and CA1

Stefanini, F.; Kheirbek, M. A.; Kushnir, L.; Jimenez, J. C.; Jennings, J. H.; Stuber, G. D.; Hen, R.; Fusi, S.

10.1101/292953 — neuroscience — Posted on 2019-02-28

132 A projection specific logic to sampling visual inputs in mouse superior colliculus

Reinhard, K.; Li, C.; Do, Q.; Burke, E.; Heynderickx, S.; Farrow, K.

10.1101/272914 — neuroscience — Posted on 2019-02-28

133 KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity

Turberfield, A. H.; Kondo, T.; Nakayama, M.; Koseki, Y.; King, H. W.; Koseki, H.; Klose, R. J.

10.1101/561571 — molecular biology — Posted on 2019-02-28

134 Non-homologous end joining minimizes errors by coordinating DNA processing with ligation

Stinson, B. M.; Moreno, A. T.; Walter, J. C.; Loparo, J. J.

10.1101/563197 — molecular biology — Posted on 2019-02-28

135 Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers

Nakagaki-Silva, E. E.; Gooding, C.; Llorian, M.; Jacob, A. G.; Richards, F.; Buckroyd, A.; Sinha, S.; Smith, C. W.

10.1101/563304 — molecular biology — Posted on 2019-02-28

136 The Tug1 Locus is Essential for Male Fertility

Lewandowski, J. P.; Dumbovic, G.; Watson, A. R.; Hwang, T.; Jacobs-Palmer, E.; Chang, N.; Much, C.; Turner, K.; Kirby, C.; Felicitas Schulz, J.; Müller, C.-L.; Rubinstein, N. D.; Groff, A. F.; Liapis, S. C.; Gerhardinger, C.; Hubner, N.; van Heesch, S.; Hoekstra, H. E.; Sauvageau, M.; Rinn, J. L.

10.1101/562066 — genomics — Posted on 2019-02-28

137 PARASITES MEDIATE CONDITION-DEPENDENT SEXUAL SELECTION FOR LOCAL ADAPTATION IN A NATURAL INSECT POPULATION

Gomez, M.; Narasimhan, A.; Svensson, E.

10.1101/563874 — evolutionary biology — Posted on 2019-02-28

138 The Genomic Ecosystem of Transposable Elements in Maize

Stitzer, M. C.; Anderson, S. N.; Springer, N. M.; Ross-Ibarra, J.

10.1101/559922 — evolutionary biology — Posted on 2019-02-28

139 Dinucleoside polyphosphates act as 5'-RNA caps in Escherichia coli

Hudecek, O.; Benoni, R.; Culka, M.; Hubalek, M.; Rulisek, L.; Cvacka, J.; Cahova, H.

10.1101/563817 — molecular biology — Posted on 2019-02-28

140 Dynamic chromatin targeting of BRD4 stimulates cardiac fibroblast activation

Stratton, M. S.; Bagchi, R. A.; Hirsch, R. A.; Riching, A. S.; Felisbino, M. B.; Enyart, B. Y.; Koch, K. A.; Cavasin, M. A.; Alexanian, M.; Song, K.; Qi, J.; Lemieux, M. E.; Lam, M. P. Y.; Haldar, S. M.; Lin, C. Y.; McKinsey, T.

10.1101/563445 — molecular biology — Posted on 2019-02-28

141 A generic approach for studying the kinetics of liquid-liquid phase separation under near-native conditions

van Lindt, J.; Bratek-Skicki, A.; Bratek-Skicki, A.; Pakravan, D.; Van Den Bosch, L.; Maes, D.; Tompa, P.

10.1101/563700 — molecular biology — Posted on 2019-02-28

142 The Abnormal Oswald Ripening of Protein Nanofiber in Myofibrillar Protein Solution

Niu, F.; Zhang, R.; Fan, J.; Pan, W.

10.1101/558460 — biophysics — Posted on 2019-02-28

143 Reconciling simulated ensembles of apomyoglobin with experimental HDX data using Bayesian inference and multi-ensemble Markov State Models

Wan, H.; Ge, Y.; Razavi, A.; Voelz, V. A.

10.1101/563320 — biophysics — Posted on 2019-02-28

144 Probing Ligand and Cation Binding Sites in G-Quadruplex Nucleic Acids by Mass Spectrometry and Electron Photodetachment Dissociation Sequencing

Paul, D.; Marchand, A.; Verga, D.; Bombard, S.; Teulade-Fichou, M.-P.; Rosu, F.; Gabelica, V.

10.1101/563627 — biophysics — Posted on 2019-02-28

145 Evolutionary model of protein secondary structure capable of revealing new biological relationships

Lai, J.-S.; Rost, B.; Kobe, B.; Boden, M.

10.1101/563452 — bioinformatics — Posted on 2019-02-28

146 Drug screens of NGLY1 Deficiency worm and fly models reveal catecholamine, NRF2 and anti-inflammatory pathway activation as clinical approaches

Iyer, S.; Mast, J. D.; Tsang, H.; Rodriguez, T. P.; DiPrimio, N.; Prangley, M.; Sam, F. S.; Parton, Z. M.; Perlstein, E.

10.1101/563478 — pharmacology and toxicology — Posted on 2019-02-28

147 UDCT: Unsupervised data to content transformation with histogram-matching cycle-consistent generative adversarial networks

Stephan, I. J.; Reichmuth, A. M.; Girardin, S.; Han, H.; Stauffer, F.; Bonnin, A.; Stampanoni, M. F. M.; Voros, J.; Forro, C.

10.1101/563734 — bioengineering — Posted on 2019-02-28

148 Information Flow in Planar Polarity

Fisher, K. H.; Strutt, D. I.; Fletcher, A. G.

10.1101/236836 — systems biology — Posted on 2019-02-28

149 Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast

Asakawa, H.; Kojidani, T.; Yang, H.-J.; Ohtsuki, C.; Osakada, H.; Matsuda, A.; Iwamoto, M.; Chikashige, Y.; Nagao, K.; Obuse, C.; Hiraoka, Y.; Haraguchi, T.

10.1101/223131 — cell biology — Posted on 2019-02-28

150 Identification of 67 pleiotropic genes for seven autoimmune diseases using multivariate statistical analysis

Jia, X.; Shi, N.; Xia, Z.; Feng, Y.; Li, Y.; Tan, J.; Xu, F.; Wang, W.; Sun, C.; Deng, H.; Yang, Y.; Shi, X.

10.1101/563973 — genetics — Posted on 2019-02-28

151 Erythropoiesis differences in various clinical phases of Dengue fever using Immature Reticulocyte Fraction parameter

Oehadian, A.; Vidyaniati, P.; Candra, J. M.; Sumardi, U.; Susandi, E.; Alisjahbana, B.

10.1101/563924 — microbiology — Posted on 2019-02-28

152 SNAP23 is required for the maintenance of meiotic arrest and cortical granule exocytosis in mouse oocytes

Mehlmann, L. M.; Uliasz, T. F.; Lowther, K. M.

10.1101/562843 — cell biology — Posted on 2019-02-28

153 Integrated Phosphoproteomics and Transcriptional Classifiers Reveal Hidden RAS Signaling Dynamics in Multiple Myeloma

Lin, Y.-H. T.; Way, G. P.; Barwick, B. G.; Mariano, M. C.; Marcoulis, M.; Ferguson, I. D.; Driessen, C.; Boise, L. H.; Greene, C. S.; Wiita, A. P.

10.1101/563312 — cancer biology — Posted on 2019-02-28

154 Easy Two-Photon Image Scanning Microscopy with SPAD Array and Blind Image Reconstruction

Koho, S. V.; Slenders, E.; Tortarolo, G.; Castello, M.; Buttafava, M.; Villa, F.; Tcarenkova, E.; Ameloot, M.; Bianchini, P.; Sheppard, C. J. R.; Diaspro, A.; Tosi, A.; Vicidomini, G.

10.1101/563288 — bioengineering — Posted on 2019-02-28

155 Pan-cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia

Chang, W. H.; Lai, A. G.

10.1101/563676 — cancer biology — Posted on 2019-02-28

156 A biophysical model of Epithelial-Mesenchymal Transition uncovers the frequency and size distribution of Circulating Tumor Cell clusters across cancer types

Bocci, F.; Kumar Jolly, M.; Onuchic, J. N.

10.1101/563049 — biophysics — Posted on 2019-02-28

157 Transcriptional variation in glucosinolate biosynthetic genes and inducible responses to aphid herbivory on field-grown Arabidopsis thaliana

Sato, Y.; Tezuka, A.; Kashima, M.; Deguchi, A.; Shimizu-Inatsugi, R.; Yamazaki, M.; Shimizu, K. K.; Nagano, A. J.

10.1101/563486 — plant biology — Posted on 2019-02-28

158 The effect of drought and intercropping on chicory nutrient uptake from below 2 m studied in a multiple tracer setup

Rasmussen, C. R.; Thorup-Kristensen, K.; Dresboell, D. B.

10.1101/562876 — plant biology — Posted on 2019-02-28

159 A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength

Afshar, M. E.; Abraha, H. Y.; Bakooshli, M. A.; Davoudi, S.; Thavandiran, N.; Tung, K.; Ahn, H.; Ginsberg, H.; Zandstra, P. W.; Gilbert, P. M.

10.1101/562819 — bioengineering — Posted on 2019-02-28

160 Altered Cell-Substrate Behavior on Microporous Membranes is a Result of Disruption and Grip

Allahyari, Z.; Gholizadeh, S.; Chung, H.; Delgadillo, L.; Gaborski, T.

10.1101/563361 — bioengineering — Posted on 2019-02-28

161 Flowering behaviour in Arabis alpina ensures the maintenance of a perennating dormant bud bank

Vayssieres, A.; Mishra, P.; Roggen, A.; Ponraj, U.; Neumann, U.; Theres, K.; Ljung, K.; Albani, M. C.

10.1101/562868 — plant biology — Posted on 2019-02-28

162 Optical properties of living corals determined with diffuse reflectance spectroscopy

Jacques, S.; Wangpraseurt, D.; Kuhl, M.

10.1101/563106 — plant biology — Posted on 2019-02-28

163 Saxitoxin and tetrodotoxin bioavailability increases in future oceans

Roggatz, C. C.; Fletcher, N.; Benoit, D. M.; Algar, A. C.; Doroff, A.; Wright, B.; Wollenberg Valero, K. C.; Hardege, J. D.

10.1101/562694 — pharmacology and toxicology — Posted on 2019-02-28

164 Field application of an eDNA assay for the threatened white-clawed crayfish Austropotamobius pallipes

Atkinson, S. S.; Carlsson, J. E. L.; Ball, B.; Kelly-Quinn, M.; Carlsson, J.

10.1101/562710 — genetics — Posted on 2019-02-28

165 A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

Sybirna, A.; Tang, W. W. C.; Dietmann, S.; Gruhn, W. H.; Surani, A. M.

10.1101/563072 — developmental biology — Posted on 2019-02-27

166 Targeting endometrial cancer stem cell activity with metformin is inhibited by patient-derived adipocyte-secreted factors

Kitson, S. J.; Rosser, M.; Fischer, D. P.; Marshall, K. M.; Clarke, R. B.; Crosbie, E. J.

10.1101/562744 — cancer biology — Posted on 2019-02-28

167 RUNX/CBFβ transcription factor complexes promote the phenotypic plasticity of metastatic breast cancer cells

Ran, R.; Harrison, H.; Ariffin, N. S.; Ayub, R.; Pegg, H.; Deng, W.; Mastro, A.; Ottewell, P.; Fowles, A.; Mason, S.; Blythe, K.; Holen, I.; Shore, P.

10.1101/562538 — cancer biology — Posted on 2019-02-27

168 Self-reported Health is Related to Body Height and Waist Circumference in Rural Indigenous and Urbanized Latin-American Populations

Leongomez, J. D.; Sanchez, O. R.; Vasquez-Amezquita, M.; Valderrama, E.; Castellanos-Chacon, A.; Morales-Sanchez, L.; Nieto, J.; Gonzalez-Santoyo, I.

10.1101/562942 — evolutionary biology — Posted on 2019-02-27

169 Embedding single-cell experimental conditions to reveal manifold structure of cancer drug perturbation effects

Chen, W. S.; Zivanovic, N.; van Dijk, D.; Wolf, G.; Bodenmiller, B.; Krishnaswamy, S.

10.1101/455436 — bioinformatics — Posted on 2019-02-27

170 A metapopulation model for the 2018 Ebola virus disease outbreak in Equateur province in the Democratic Republic of the Congo

Meakin, S.; Tildesley, M.; Davis, E.; Keeling, M.

10.1101/465062 — epidemiology — Posted on 2019-02-27

171 Discrete Mechanical Growth Model for Plant Tissue

Weise, L. D.; ten Tusscher, K. H. W. J.

10.1101/459412 — biophysics — Posted on 2019-02-27

172 Analysis of multiple fungal sequence repositories highlights shortcomings in microbial databases

Loeffler, C.; Karlsberg, A.; Eskin, E.; Koslicki, D.; Mangul, S.

10.1101/497867 — bioinformatics — Posted on 2019-02-27

173 Anosognosia for Hemiplegia as a tripartite disconnection syndrome

Pacella, V.; Foulon, C.; Jenkinson, P.; Scandola, M.; Bertagnoli, S.; Avesani, R.; Fotopoulou, K.; Moro, V.; Thiebaut de Schotten, M.

10.1101/560326 — neuroscience — Posted on 2019-02-27

174 Can we predict which species win when new habitat becomes available?

Nomura, M.; Ohlemüller, R.; Lee, W. G.; Lloyd, K. M.; Anderson, B. J.

10.1101/562959 — ecology — Posted on 2019-02-27

175 Absolute quantification of cohesin, CTCF and their regulators in human cells

Holzmann, J.; Politi, A. Z.; Nagasaka, K.; Hantsche-Grininger, M.; Walther, N.; Koch, B.; Fuchs, J.; Dürnberger, G.; Tang, W.; Ladurner, R.; Stocsits, R. R.; Busslinger, G. A.; Novak, B.; Mechtler, K.; Davidson, I. F.; Ellenberg, J.; Peters, J.-M.

10.1101/560425 — cell biology — Posted on 2019-02-27

176 Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock

Castelo-Szekely, V.; De Matos, M.; Tusup, M.; Pascolo, S.; Ule, J.; Gatfield, D.

10.1101/407551 — genomics — Posted on 2019-02-27

177 An image-based assay to quantify changes in proliferation and viability upon drug treatment in 3D microenvironments

Siruvallur Murali, V.; Chang, B.-J.; Fiolka, R.; Danuser, G.; Cobanoglu, M. C.; Welf, E.

10.1101/312504 — cancer biology — Posted on 2019-02-27

178 p62-mediated Selective Autophagy Endows Virus-transformed Cells with Insusceptibility to DNA Damage under Oxidative Stress

Wang, L.; Howell, M.; Sparks-Wallace, A.; Hawkins, C.; Nicksic, C.; Kohne, C.; Hall, K.; Moorman, J.; Yao, Z. Q.; Ning, S.

10.1101/502823 — cancer biology — Posted on 2019-02-27

179 The Ps and Qs of alarmone synthesis in Staphylococcus aureus

Yang, N.; Xie, S.; Choi, M. Y.; Wang, Y.; Watt, R. M.; Tang, N.-Y.

10.1101/562918 — biochemistry — Posted on 2019-02-27

180 Increased Replication Rates of Dissimilatory Nitrogen-Reducing Bacteria Leads to Decreased Anammox Reactor Performance

Keren, R.; Lawrence, J.; Zhuang, W.-Q.; Jenkins, D.; Banfield, J. F.; Alvarez-Cohen, L.; Zhou, L.; Yu, K.

10.1101/534925 — microbiology — Posted on 2019-02-27

181 The Crohn s disease-associated Escherichia coli strain LF82 rely on SOS and stringent responses to survive, multiply and tolerate antibiotics within macrophages.

Demarre, G.; Prudent, V.; Schenk, H.; Rousseau, E.; Bringer, M.-A.; Barnich, N.; Tran Van Nhieu, G.; Rimsky, S.; De Monte, S.; Espeli, O.

10.1101/551226 — microbiology — Posted on 2019-02-27

182 Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

Warr, A. R.; Hubbard, T. P.; Munera, D.; Blondel, C. J.; Abel zur Wiesch, P.; Abel, S.; Wang, X.; Davis, B. M.; Waldor, M. K.

10.1101/563007 — microbiology — Posted on 2019-02-27

183 The genome and mRNA transcriptome of the cosmopolitan calanoid copepod Acartia tonsa Dana improve the understanding of copepod genome size evolution

Jorgensen, T. S.; Petersen, B.; Petersen, H. C. B.; Browne, P. D.; Prost, S.; Stillman, J.; Hestbjerg Hansen, L.; Hansen, B. W.

10.1101/560102 — genomics — Posted on 2019-02-27

184 Spatio-temporal dynamics of face perception

Muukkonen, I.; Olander, K.; Numminen, J.; Salmela, V.

10.1101/550038 — neuroscience — Posted on 2019-02-27

185 Comparison of different orders of Legendre polynomials in random regression model for estimation of genetic parameters and breeding values of milk yield in the Chinese Holstein population

Li, J.; Gao, H.; Madsen, P.; Liu, W.; Bao, P.; Xue, G.; Yang, J.; Gao, Y.; Su, G.

10.1101/562991 — genetics — Posted on 2019-02-27

186 Continent-scale phenotype mapping using photographs from citizen scientists

Drury, J. P.; Barnes, M.; Finneran, A. E.; Harris, M.; Grether, G. F.

10.1101/503847 — evolutionary biology — Posted on 2019-02-27

187 Sub-district Costs and Efficiency of the Re Mmogo Pholong (\"Together in Wellness\") Combination HIV/AIDS Prevention Intervention in the North West Province of South Africa

Kevany, S.

10.1101/562926 — epidemiology — Posted on 2019-02-27

188 Thermal sensors improve wrist-worn position tracking

Son, J.; Clucas, J.; White, C.; Vogelstein, J.; Milham, M.; Klein, A.

10.1101/552174 — bioinformatics — Posted on 2019-02-27

189 A distributed neural code in the dentate gyrus and CA1

Stefanini, F.; Kheirbek, M. A.; Kushnir, L.; Jimenez, J. C.; Jennings, J. H.; Stuber, G. D.; Hen, R.; Fusi, S.

10.1101/292953 — neuroscience — Posted on 2019-02-27

190 ciftify: A framework for surface-based analysis of legacy MR acquisitions

Dickie, E. W.; Anticevic, A.; Smith, D. E.; Coalson, T. S.; Manogaran, M.; Calarco, N.; Viviano, J. D.; Glasser, M. F.; Van Essen, D. C.; Voineskos, A. N.

10.1101/484428 — neuroscience — Posted on 2019-02-27

191 Comparing Task-Relevant Information Across Different Methods of Extracting Functional Connectivity

Benitez Stulz, S.; Insabato, A.; Deco, G.; Gilson, M.; Senden, M.

10.1101/509059 — neuroscience — Posted on 2019-02-27

192 Bessel beam tomography for fast volume imaging

Flores Valle, A.; Seelig, J.

10.1101/552661 — neuroscience — Posted on 2019-02-27

193 Photoperiod-induced neurotransmitter plasticity declines with aging: an epigenetic regulation?

Pritchard, R.; Chen, H.; Romoli, B.; Spitzer, N. C.; Dulcis, D.

10.1101/563213 — neuroscience — Posted on 2019-02-27

194 Growth characteristics of pneumococcus vary with the chemical composition of the capsule and with environmental conditions

Tothpal, A.; Desobry, K.; Joshi, S.; Wyllie, A. L.; Weinberger, D. M.

10.1101/416040 — microbiology — Posted on 2019-02-27

195 PCAGO: An interactive web service to analyze RNA-Seq data with principal component analysis

Gerst, R.; Hölzer, M.

10.1101/433078 — bioinformatics — Posted on 2019-02-27

196 A re-interpretation of the experimental data of Shinder and Taube \"Three-dimensional Tuning of Head Direction Cells in Rats\", Journal of Neurophysiology 121(1), 2019.

Laurens, J.; Angelaki, D.

10.1101/559336 — neuroscience — Posted on 2019-02-27

197 The effect of cathodal tDCS on fear extinction: a cross-measures study

Ganho-Avila, A.; Goncalves, O. F.; Guiomar, R.; Boggio, P. S.; Asthana, M. K. K.; Krypotos, A.-M.; Almeida, J.

10.1101/561803 — neuroscience — Posted on 2019-02-27

198 Monetary feedback modulates performance and electrophysiological indices of belief updating in reward learning

Bennett, D.; Sasmita, K.; Maloney, R. T.; Murawski, C.; Bode, S.

10.1101/183665 — neuroscience — Posted on 2019-02-27

199 Inverted translational control of eukaryotic gene expression by ribosome collisions

Park, H.; Subramaniam, A. R.

10.1101/562371 — molecular biology — Posted on 2019-02-27

200 A global survey of mycobacterial diversity in soil

Walsh, C. M.; Gebert, M. J.; Delgado-Baquerizo, M.; Maestre, F.; Fierer, N.

10.1101/562439 — microbiology — Posted on 2019-02-27

201 CD29 marks superior cytotoxic human T cells

Nicolet, B. P.; Guislain, A.; van Alphen, F. P. J.; Gomez-Eerland, R.; Schumacher, T. N. M.; van den Biggelaar, M.; Wolkers, M.

10.1101/562512 — immunology — Posted on 2019-02-27

202 Instability of the pseudoautosomal boundary in house mice

Morgan, A. P.; Bell, T. A.; Crowley, J. J.; Pardo Manuel de Villena, F.

10.1101/561951 — genetics — Posted on 2019-02-27

203 Proteins encoded by Novel ORFs have increased disorder but can be biochemically regulated and harbour pathogenic mutations

Jagannathan, N. S.; Meena, N.; Bhayankaram, K. P.; Prabakaran, S.

10.1101/562835 — genetics — Posted on 2019-02-27

204 Self-reported Health is Related to Body Height and Waist Circumference in Rural Indigenous and Urbanized Latin-American Populations

Leongomez, J. D.; Sanchez, O. R.; Vasquez-Amezquita, M.; Valderrama, E.; Castellanos-Chacon, A.; Morales-Sanchez, L.; Nieto, J.; Gonzalez-Santoyo, I.

10.1101/562942 — evolutionary biology — Posted on 2019-02-27

205 A data-driven method to locate nest sites and estimate reproductive outcome from avian telemetry data

Picardi, S.; Smith, B. J.; Boone, M. E.; Frederick, P. C.; Cecere, J. G.; Rubolini, D.; Serra, L.; Pirrello, S.; Borkhataria, R. R.; Basille, M.

10.1101/562025 — ecology — Posted on 2019-02-27

206 Axonemal doublet microtubules can split into two complete singlets in human sperm flagellum tips

Zabeo, D.; Croft, J. T.; Hoog, J. L.

10.1101/562777 — cell biology — Posted on 2019-02-27

207 Gene Expression Modulation by the Linker of Nucleoskeleton and Cytoskeleton Complex Contributes to Proteostasis

Levine, A.; Grushko, D.; Cohen, E.

10.1101/548859 — cell biology — Posted on 2019-02-27

208 De novo compartment deconvolution and weight estimation of tumor samples (DECODER)

Peng, X. L.; Moffitt, R. A.; Torphy, R. J.; Volmar, K. E.; Yeh, J. J.

10.1101/561647 — bioinformatics — Posted on 2019-02-27

209 Mouse Model Systems of Autism Spectrum Disorder: Replicability and Informatics Signature

Kabitzke, P. A.; Morales, D.; He, D.; Cox, K.; Sutphen, J.; Thiede, L.; Sabath, E.; Hanania, T.; Biemans, B.; Brunner, D.

10.1101/561233 — animal behavior and cognition — Posted on 2019-02-27

210 Diversity of Escherichia coli from the enteric microbiota in patients with Escherichia coli bacteraemia

Mosavie, M.; Blandy, O.; Jauneikaite, E.; Caldas, I.; Ellington, M. J.; Woodford, N.; Sriskandan, S.

10.1101/561613 — microbiology — Posted on 2019-02-27

211 Density-dependent selection mediates harvest-induced evolution

Bouffet-Halle, A.; Mériguet, J.; Carmignac, D.; Agostini, S.; Millot, A.; Perret, S.; Motard, E.; Decenciere, B.; Edeline, E.

10.1101/561522 — evolutionary biology — Posted on 2019-02-27

212 Thyroid hormone coordinates developmental trajectories but does not underlie developmental truncation in Danionins

Hu, Y.; Mauri, A.; Donahue, J.; Singh, R.; Acosta, B.; McMenamin, S. K.

10.1101/562074 — developmental biology — Posted on 2019-02-27

213 Use of CRISPR/Cas9 Gene Targeting to Conditionally Delete Glucocorticoid Receptors in Rat Brain

Scheimann, J. R.; Moloney, R. D.; Mahbod, P.; Morano, R. L.; Fitzgerald, M.; Hoskins, O.; Packard, B. A.; Hu, Y.-C.; Herman, J. P.

10.1101/560946 — neuroscience — Posted on 2019-02-27

214 The pseudogene SURFIN 4.1 is vital for merozoite formation in blood stage P. falciparum

Macedo Silva, T.; Duque Araujo, R. B.; Wunderlich, G.

10.1101/562124 — microbiology — Posted on 2019-02-27

215 The high persister phenotype of Pseudomonas aeruginosa is associated with increased fitness and persistence in cystic fibrosis airways

Mojsoska, B.; Cameron, D. R.; Bartell, J. A.; Haagensen, J. A.; Sommer, L. M.; Lewis, K.; Molin, S.; Johansen, H. K.

10.1101/561589 — microbiology — Posted on 2019-02-27

216 Amplification-free Library Preparation Improves Quality of Hi-C Analysis

Niu, L.; Shen, W.; Huang, Y.; He, N.; Zhang, Y.; Sun, J.; Wan, J.; Jiang, D.; Yang, M.; Tse, Y. C.; Li, L.; Hou, C.

10.1101/562280 — genomics — Posted on 2019-02-27

217 Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty

Kalra, G.; Milon, B.; Casella, A. M.; Song, Y.; Herb, B. R.; Rose, K. P.; Hertzano, R.; Ament, S.

10.1101/562405 — genetics — Posted on 2019-02-27

218 The great tit HapMap project: a continental-scale analysis of genomic variation in a songbird

Spurgin, L. G.; Bosse, M.; Adriaensen, F.; Albayrak, T.; Barboutis, C.; Belda, E.; Bushuev, A.; Cecere, J.; Charmantier, A.; Cichon, M.; Dingemanse, N. J.; Doligez, B.; Eeva, T.; Erikstad, K. E.; Federov, V.; Griggio, M.; Heylen, D.; Hille, S.; Hinde, C.; Ivankina, E.; Laine, V. N.; Kempenaers, B.; Kerimov, A.; Krist, M.; Kvist, L.; Mänd, R.; Matthysen, E.; Nager, R.; Nikolov, B.; Norte, C.; Orell, M.; Ouyang, J.; Petrova-Dinkova, G.; Richner, H.; Rubolini, D.; Slagsvold, T.; Tilgar, V.; Török, J.; Tschirren, B.; Vagasi, C. I.; Yuta, T.; Groenen, M. A. M.; Visser, M. E.; van Oers, K.; Sheld

10.1101/561399 — evolutionary biology — Posted on 2019-02-27

219 Population responses of naive roe deer to the recolonization of the French Vercors by wolves

Randon, M.; Bonenfant, C.; Michallet, J.; Chevrier, T.; Toïgo, C.; Gaillard, J.-M.; VALEIX, M.

10.1101/560128 — ecology — Posted on 2019-02-27

220 STOCHASTIC SINGLE CELL BEHAVIOUR LEADS TO ROBUST HORIZONTAL CELL LAYER FORMATION IN THE VERTEBRATE RETINA

Amini, R.; Labudina, A.; Norden, C.

10.1101/561449 — developmental biology — Posted on 2019-02-27

221 Modeling the Human Segmentation Clock with Pluripotent Stem Cells

Matsuda, M.; Yamanaka, Y.; Uemura, M.; Osawa, M.; Saito, M. K.; Nagahashi, A.; Nishio, M.; Guo, L.; Ikegawa, S.; Sakurai, S.; Kihara, S.; Nakamura, M.; Matsumoto, T.; Yoshitomi, H.; Ikeya, M.; Yamamoto, T.; Woltjen, K.; Ebisuya, M.; Toguchida, J.; Alev, C.

10.1101/562447 — developmental biology — Posted on 2019-02-27

222 Allosteric structural alterations and auto-regulation of Rab5 GEF activity in Rabex5

Lauer, J.; Cezanne, A.; Guaitoli, G.; Raimondi, F.; Gentzel, M.; Alva, V.; Habeck, M.; Ueffing, M.; Lupas, A. N.; Gloeckner, C. J.; Zerial, M.

10.1101/562504 — biophysics — Posted on 2019-02-27

223 Ontology-based prediction of cancer driver genes

Althubaiti, S.; Karwath, A.; Dallol, A.; Noor, A.; Alkhayyat, S. S.; Alwassia, R.; Mineta, K.; Gojobori, T.; Beggs, A. D.; Schofield, P. N.; Gkoutos, G. V.; Hoehndorf, R.

10.1101/561480 — bioinformatics — Posted on 2019-02-27

224 fragilityindex: An R Package for Statistical Fragility Estimates in Biomedicine

Johnson, K. W.; Rappaport, E.; Khader, S.; Glicksberg, B. S.; Dudley, J. T.

10.1101/562264 — bioinformatics — Posted on 2019-02-27

225 Diurnal variations in serum metabolites of wintering redheaded buntings.

Nanda, R.; Jain Gupta, N.; Das, S.; Das, M.; Arya, R.

10.1101/561407 — animal behavior and cognition — Posted on 2019-02-27

226 Analyzing time-aggregated networks: the role of bootstrapping, permutation, and simulation.

Bonnell, T. R.; Vilette, C.

10.1101/562231 — animal behavior and cognition — Posted on 2019-02-27

227 FINE-SCALE POPULATION GENETIC STRUCTURE OF DENGUE MOSQUITO VECTOR, Aedes aegypti AND ITS ASSOCIATION TO LOCAL DENGUE INCIDENCE

CARVAJAL, T. M.; Ogishi, K.; Yaegeshi, S.; Hernandez, L. F. T.; Viacrusis, K. M.; Ho, H. T.; Amalin, D. M.; Watanabe, K.

10.1101/561621 — zoology — Posted on 2019-02-27

228 Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination

Hoff, K. D.; Halpain, M.; Garbagnati, G.; Edwards, J.; Zhou, W.

10.1101/561092 — synthetic biology — Posted on 2019-02-27

229 Clinical Significance of C4d Deposition in Renal Tissues from Patients with Primary Sj&oumlgren's Syndrome--A Preliminary Study

Xia, W.; Gao, B.; Duan, L.; Li, Y.; Wen, Y.; Chen, L.; Li, X.; Zheng, F.; Li, M.

10.1101/562215 — pathology — Posted on 2019-02-27

230 Defining region-specific masks for reliable depth-dependent analysis of fMRI data

Weldon, K. B.; Burton, P. C.; Grant, A. N.; Yacoub, E.; Olman, C. A.

10.1101/557363 — neuroscience — Posted on 2019-02-27

231 Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin

Martin-Perez, M.; Ito, T. K.; Grillo, A. S.; Valente, A. S.; Han, J.; Entwisle, S. W.; Huang, H. Z.; Kim, D.; Yajima, M.; Kaeberlein, M.; Villen, J.

10.1101/562207 — neuroscience — Posted on 2019-02-27

232 A new pathway of pre-tRNA surveillance in yeast

Payea, M. J.; De Zoysa, T. C.; Phizicky, E. M.

10.1101/561944 — molecular biology — Posted on 2019-02-27

233 Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association

Wang, Y.; Brady, K. S.; Caiello, B.; Ackerson, S. M.; Stewart, J.

10.1101/561977 — molecular biology — Posted on 2019-02-27

234 Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling

El Houdaigui, B.; Forquet, R.; Hindre, T.; Schneider, D.; Nasser, W.; Reverchon, S.; Meyer, S.

10.1101/561423 — microbiology — Posted on 2019-02-27

235 Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway

Kundlacz, C.; Pourcelot, M.; Fablet, A.; Amaral Da Silva Moraes, R.; Leger, T.; Morlet, B.; Viarouge, C.; Sailleau, C.; Turpaud, M.; Gorlier, A.; Breard, E.; Lecollinet, S.; van Rijn, P. A.; Zientara, S.; Vitour, D.; Caignard, G.

10.1101/562421 — microbiology — Posted on 2019-02-27

236 Interplay between the human gut microbiome and host metabolism

Visconti, A.; Le Roy, C. I.; Rosa, F.; Rossi, N.; Martin, T. C.; Mohney, R. P.; Weizhong, L.; de Rinaldis, E.; Bell, J. T.; Venter, J. C.; Nelson, K. E.; Spector, T. D.; Falchi, M.

10.1101/561787 — microbiology — Posted on 2019-02-27

237 Latent Mycobacterium tuberculosis infection provides protection for the host by changing the activation state of the innate immune system

Nemeth, J.; Olson, G. S.; Rothchild, A.; Jahn, A.; Mai, D.; Duffy, F.; Delahaye, J.; Srivatsan, S.; Plumlee, C.; Urdahl, K.; Gold, E.; Diercks, A.; Aderem, A.

10.1101/561126 — immunology — Posted on 2019-02-27

238 Single cell ATAC-seq identifies broad changes in neuronal abundance and chromatin accessibility in Down Syndrome

Spektor, R.; Yang, J. W.; Lee, S.; Soloway, P. D.

10.1101/561191 — genomics — Posted on 2019-02-27

239 A Comprehensive Assessment of Demographic, Environmental and Host Genetic Associations with Gut Microbiome Diversity in Healthy Individuals

Scepanovic, P.; Hodel, F.; Mondot, S.; Partula, V.; Byrd, A.; Hammer, C.; Alanio, C.; Bergstedt, J.; Patin, E.; Touvier, M.; Lantz, O.; Albert, M. L.; Duffy, D.; Quintana-Murci, L.; Fellay, J.; The Milieu Interieur Consortium,

10.1101/557124 — genomics — Posted on 2019-02-27

240 Comparative Genomics of Six Juglans Species Reveals Patterns of Disease-associated Gene Family Contractions.

Trouern-Trend, A. J.; Falk, T. A.; Zaman, S.; Caballero, M.; Neale, D. B.; Langley, C. H.; Dandekar, A.; Stevens, K.; Wegrzyn, J.

10.1101/561738 — genomics — Posted on 2019-02-27

241 Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinsons disease

Whiffin, N.; Armean, I. M.; Kleinman, A.; Marshall, J. L.; Minikel, E. V.; Karczewski, K. J.; Cummings, B. B.; Francioli, L.; Laricchia, K.; Wang, Q.; Guan, A.; Alipanahi, B.; Morrison, P.; Baptista, M. A.; Merchant, K. M.; Genome Aggregation Database Production Team, ; Genome Aggregation Database Consortium, ; Ware, J. S.; Havulinna, A. S.; Iliadou, B.; Lee, J.-J.; Nadkarni, G. N.; Whiteman, C.; the 23andMe Research Team, ; Daly, M.; Esko, T.; Hultman, C.; Loos, R. J.; Milani, L.; Palotie, A.; Pato, C.; Pato, M.; Saleheen, D.; Sullivan, P. F.; Alföldi, J.; Cannon, P.; MacArthur, D. G.

10.1101/561472 — genomics — Posted on 2019-02-27

242 RumimiR: a detailed microRNA database focused on ruminant species

Bourdon, C.; Bardou, P.; Aujean, E.; Le Guillou, S.; Tosser-Klopp, G.; LE PROVOST, F.

10.1101/561720 — genomics — Posted on 2019-02-27

243 LD scores are associated with differences in allele frequencies between populations but LD score regression can still distinguish confounding from polygenicity

Alexander, M.; Curtis, D.

10.1101/562629 — genetics — Posted on 2019-02-27

244 Feeding kinematics and morphology of the alligator gar (Atractosteus spatula, Lacepede, 1803)

Lemberg, J. B.; Shubin, N. H.; Westneat, M. W.

10.1101/561993 — evolutionary biology — Posted on 2019-02-27

245 Optimised FRET pairs and quantification approaches to detect the activation of Aurora kinase A at mitosis

Bertolin, G.; Sizaire, F.; Demeautis, C.; Chapuis, C.; Merola, F.; Erard, M.; Tramier, M.

10.1101/562603 — cell biology — Posted on 2019-02-27

246 Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer

Tiwari, R.; Manzar, N.; Bhatia, V.; Yadav, A.; Carskadon, S.; Gupta, N.; Zoubeidi, A.; Palanisamy, N.; Ateeq, B.

10.1101/562652 — cancer biology — Posted on 2019-02-27

247 Molecular Dynamics Simulations of Glycosaminoglycan Oligosaccharide Using Newer Force Fields

Nagarajan, B.; Sankaranarayanan, N. V.; Desai, U. R.

10.1101/561969 — biophysics — Posted on 2019-02-27

248 PathRacer: racing profile HMM paths on assembly graph

Shlemov, A.; Korobeynikov, A.

10.1101/562579 — bioinformatics — Posted on 2019-02-27

249 CHilEnPred: CNN Model With Hilbert Curve Representation of DNA Sequence For Enhancer Prediction

Anjum, M. M.; Tahmid, I. A.; Rahman, M. S.

10.1101/552141 — bioinformatics — Posted on 2019-02-27

250 Comprehensive bioinformatics analysis of L1CAM gene revealed Novel Pathological mutations associated with L1 syndrome

Murshed, N. S.; Mustafa, M. I.; Abdelmoneim, A. H.; Mahmoud, T. A.; Elfadol, N. M.; Hassan, M. A.

10.1101/561431 — bioinformatics — Posted on 2019-02-27

251 Saccadic suppression by way of retinal-circuit image processing

Idrees, S.; Baumann, M.-P.; Franke, F.; Muench, T. A.; Hafed, Z. M.

10.1101/562595 — neuroscience — Posted on 2019-02-27

252 Quantitative Mass Spectrometry Imaging Reveals Mutation Status-independent Lack of Imatinib Penetration into Liver Metastases of Gastrointestinal Stromal Tumors

Abu Sammour, D.; Marsching, C.; Geisel, A.; Erich, K.; Schulz, S.; Ramallo Guevara, C.; Rabe, J.-H.; Marx, A.; Findeisen, P.; Hohenberger, P.; Hopf, C.

10.1101/562553 — pharmacology and toxicology — Posted on 2019-02-27

253 Stem cell derived human microglia transplanted in mouse brain to study genetic risk of Alzheimer's Disease

Mancuso, R.; Van Den Daele, J.; Fattorelli, N.; Wolfs, L.; Balusu, S.; Burton, O.; Sierksma, A.; Fourne, Y.; Poovathingal, S.; Arranz-Mendiguren, A.; Sala Frigerio, C.; Claes, C.; Serneels, L.; Theys, T.; Perry, V. H.; Verfaillie, C.; Fiers, M.; De Strooper, B.

10.1101/562561 — neuroscience — Posted on 2019-02-27

254 An ambiguous N-terminus drives the dual targeting of an antioxidant protein Thioredoxin peroxidase (TgTPx1/2) to endosymbiotic organelles in Toxoplasma gondii

Mastud, P.; Patankar, S.

10.1101/562587 — cell biology — Posted on 2019-02-27

255 Analysis of novel hyperosmotic shock response suggests \"beads in liquid\" cytosol structure

Alexandrov, A. I.; Grosfeld, E. V.; Dergalev, A. A.; Kushnirov, V. V.; Chuprov-Netochin, R. N.; Tyurin-Kuzmin, P. A.; Kireev, I. I.; Ter-Avanesyan, M. D.; Leonov, S. V.; Agaphonov, M. O.

10.1101/562728 — cell biology — Posted on 2019-02-27

256 The Hsp70/Hsp90 Co-Chaperone Hop/Stip1 Shifts the Proteostatic Balance from Folding Towards Degradation

Bhattacharya, K.; Weidenauer, L.; Moran Luengo, T.; Echeverria, P. C.; Bernasconi, L.; Wider, D.; Villemin, M.; Bauer, C.; Rüdiger, S. G. D.; Quadroni, M.; Picard, D.

10.1101/562637 — cell biology — Posted on 2019-02-27

257 Direct current stimulation boosts associative Hebbian synaptic plasticity and maintains its pathway specificity

Kronberg, G.; Rahman, A.; Lafon, B.; Bikson, M.; Parra, L. C.

10.1101/562322 — neuroscience — Posted on 2019-02-27

258 Gradients of structure-function tethering across neocortex

Rodriguez-Vazquez, B.; Suarez, L. E.; Shafiei, G.; Markello, R.; Paquola, C.; Hagmann, P.; van den Heuvel, M.; Bernhardt, B.; Spreng, R. N.; Misic, B.

10.1101/561985 — neuroscience — Posted on 2019-02-27

259 The covariance perceptron: A new framework for classification and processing of time series in recurrent neural networks

Gilson, M.; Dahmen, D.; Moreno-Bote, R.; Insabato, A.; Helias, M.

10.1101/562546 — neuroscience — Posted on 2019-02-27

260 Increased Neurite Orientation-Dispersion and Density in the TgCRND8 Mouse Model of Amyloidosis: Inverse Relation with Functional Connectome Clustering and Modulation by Interleukin-6

Colon-Perez, L. M.; Ibanez, K. R.; Suarez, M. R.; Torroella, K.; Acuna, K. R.; Ofori, E.; Levites, Y. R.; Vaillancourt, D. E.; Golde, T. E.; Chakrabarty, P.; Febo, M.

10.1101/562348 — neuroscience — Posted on 2019-02-27

261 Efficient mesoscale phenotypic screening in cultured primary neuron culture

Nedrud, D.; He, Y.; Schmidt, D.

10.1101/562298 — neuroscience — Posted on 2019-02-27

262 EpiAlignment: alignment with both DNA sequence and epigenomic data

Lu, J.; Cao, X.; Zhong, S.

10.1101/562199 — bioinformatics — Posted on 2019-02-27

263 Enzyme kinetics of tobacco Rubisco expressed in Escherichia coli varies depending on the small subunit composition

Lin, M. T.; Stone, W. D.; Chaudhari, V.; Hanson, M. R.

10.1101/562223 — plant biology — Posted on 2019-02-27

264 The differential distribution of bacteria between cancerous and noncancerous ovarian tissues in situ

Wang, Q.; Zhao, L.; Han, L.; Fu, G.; Tuo, X.; Ma, S.; Li, Q.; Wang, Y.; Liang, D.; Tang, M.; Sun, C.; Wang, Q.; Song, Q.; Li, Q.

10.1101/562975 — microbiology — Posted on 2019-02-27

265 Prototheca zopfii Genotype II induces mitochondrial apoptosis in models of bovine mastitis

Shahid, M.; Cobo, E. R.; Chen, L.; Cavalcante, P. A.; Barkema, H. W.; Gao, J.; Xu, S.; Liu, Y.; Knight, C. G.; Kastelic, J. P.; Han, B.

10.1101/562983 — microbiology — Posted on 2019-02-27

266 An MCMC-based method for Bayesian inference of natural selection from time series DNA data across linked loci

He, Z.; Dai, X.; Beaumont, M.; Yu, F.

10.1101/562967 — genetics — Posted on 2019-02-27

267 Postpartum trend in blood pressure and renal function in women with severe preeclampsia and eclampsia: A prospective cohort-study at Mulago hospital, Kampala, Uganda

Muteke, K.; Beyeza, J.; Musaba, M. W.; Wandabwa, J.; Kiondo, P.

10.1101/562934 — epidemiology — Posted on 2019-02-27

268 Development and validation of a next-gen health stratification engine to determine risk for multiple cardiovascular diseases

Rezaee, M.; Takeh, A.; Putrenko, I.; Ganna, A.; Ingelsson, E.

10.1101/562900 — bioinformatics — Posted on 2019-02-27

269 An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation

Amati, B.; Sabo, A.; Tesi, A.; De Pretis, S.; Furlan, M.; Filipuzzi, M.; Morelli, M. J.; Andronache, A.; Doni, M.; Verrecchia, A.; Pelizzola, M.

10.1101/561464 — cancer biology — Posted on 2019-02-27

270 Structural insight into the mechanism of 4-aminoquinolines selectivity for the alpha2A-adrenoceptor

Huang, N.; Li, Z.; Li, J.; Liu, L.; Deng, W.; Zhang, W.; Hou, H.; Wang, X.; Yang, Z.; Wang, X.; Chen, S.; Wang, Y.; Chen, J.

10.1101/561894 — pharmacology and toxicology — Posted on 2019-02-27

271 The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture

Di Blasio, S.; Tazzari, M.; van Wigcheren, G.; van Duffelen, A.; Stefanini, I.; Bloemendal, M.; Gorris, M.; Vasaturo, A.; Bakdash, G.; Hato, S. V.; Schalkwijk, J.; de Vries, I. J. M.; van den Bogaard, E. H.; Figdor, C. G.

10.1101/561530 — immunology — Posted on 2019-02-27

272 RanGTP regulates cilium formation and ciliary trafficking of a kinesin-II subunit independent of its nuclear functions

Huang, S.; Avasthi, P.

10.1101/562272 — cell biology — Posted on 2019-02-27

273 Divalent cations can control a switch-like behavior in heterotypic and homotypic RNA coacervates

Onuchic, P. L.; Milin, A. N.; Alshareedah, I.; Deniz, A. A.; Banerjee, P. R.

10.1101/453019 — biochemistry — Posted on 2019-02-27

274 Understanding the Athena SWAN award scheme for gender equality as a complex social intervention in a complex system: analysis of Silver award action plans in a comparative European perspective

Kalpazidou Schmidt, E.; Ovseiko, P. V.; Henderson, L. R.; Kiparoglou, V.

10.1101/555482 — scientific communication and education — Posted on 2019-02-27

275 Introgressive and horizontal acquisition of Wolbachia by Drosophila yakuba-clade hosts and horizontal transfer of incompatibility loci between distantly related Wolbachia

Cooper, B. S.; Vanderpool, D.; Conner, W. R.; Matute, D. R.; Turelli, M.

10.1101/551036 — evolutionary biology — Posted on 2019-02-27

276 Synthesis, SAR and Docking Studies of Substituted Aryl phenylthiazolyl phenylcarboxamide as potential PTP-1B Inhibitors

Varshney, K.; Gupta, A. K.; Rawat, A.; Srivastava, R.; Mishra, A.; Saxena, M.; Srivastava, A. K.; Jain, S.; Saxena, A. K.

10.1101/472670 — pharmacology and toxicology — Posted on 2019-02-27

277 Microbial Reduction of Metal-Organic Frameworks Enables Synergistic Chromium Removal

Springthorpe, S. K.; Dundas, C. M.; Keitz, B. K.

10.1101/318782 — microbiology — Posted on 2019-02-27

278 The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome

Fodor, J.; Riley, B. T.; Kass, I.; Buckle, A. M.; Borg, N. A.

10.1101/234260 — immunology — Posted on 2019-02-27

279 Two resistance nodulation division-family efflux pumps in Chromobacterium species and their role in antibiotic resistance and tolerance

Benomar, S.; Evans, K. C.; Unckless, R.; Chandler, J. R.

10.1101/562140 — microbiology — Posted on 2019-02-26

280 Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

Herberg, S.; McDermott, A. M.; Dang, P. N.; Alt, D. S.; Tang, R.; Dawahare, J. H.; Varghai, D.; Shin, J.-Y.; McMillan, A.; Dikina, A.; He, F.; Lee, Y. B.; Cheng, Y.; Umemori, K.; Wong, P. C.; Park, H.; Boerckel, J. D.; Alsberg, E.

10.1101/561837 — bioengineering — Posted on 2019-02-26

281 Recollection and prior knowledge recruit the left angular gyrus during recognition

Bellana, B.; Ladyka-Wojcik, N.; Lahan, S.; Moscovitch, M.; Grady, C.

10.1101/561910 — neuroscience — Posted on 2019-02-26

282 Divergent correlations between autism traits and multiplicative noise in fine and coarse motion discrimination tasks.

Orchard, E.; van Boxtel, J. J. A. J. A.

10.1101/561548 — neuroscience — Posted on 2019-02-26

283 Src-dependent DBL family members drive resistance to vemurafenib in human melanoma

Feddersen, C. R.; Schillo, J. L.; Varzavand, A.; Vaughn, H. R.; Wadsworth, L. S.; Voigt, A. P.; Zhu, E. Y.; Jennings, B. M.; Mullen, S. A.; Bobera, J.; Riordan, J. D.; Stipp, C. S.; Dupuy, A. J.

10.1101/561597 — cancer biology — Posted on 2019-02-26

284 Left Ventricular Chamber Shape During Vena Caval Occlusion: Improved MRI-based Measurement of the End-Systolic Pressure-Volume Relationship in Normal Sheep

Giao, D. M.; Wang, Y.; Rojas, R.; Takaba, K.; Badathala, A.; Spaulding, K. A.; Soon, G.; Zhang, Y.; Wang, V. Y.; Heraldsson, H.; Liu, J.; Saloner, D.; Ge, L.; Guccione, J. M.; Wallace, A. W.; Ratcliffe, M. B.

10.1101/562017 — bioengineering — Posted on 2019-02-26

285 Pressure overload leads to coronary plaque formation, progression and myocardial events in ApoE-/- mice

Marino, A.; Zhang, Y.; Rubinelli, L.; Ip, J. E.; Di Lorenzo, A.

10.1101/562181 — pathology — Posted on 2019-02-26

286 More Reliable EEG Electrode Digitizing Methods Can Reduce Source Estimation Uncertainty, But Current Methods Already Accurately Identify Brodmann Areas

Shirazi, S. Y.; Huang, H. J.

10.1101/557074 — neuroscience — Posted on 2019-02-26

287 Crosstalk with the GAR-3 receptor contributes to feeding defects in Caenorhabditis elegans eat-2 mutants

Kozlova, A.; Lotfi, M.; Okkema, P.

10.1101/562041 — neuroscience — Posted on 2019-02-26

288 Structural disconnections explain brain network dysfunction after stroke

Griffis, J. C.; Metcalf, N. V.; Shulman, G. L.; Corbetta, M.

10.1101/562165 — neuroscience — Posted on 2019-02-26

289 CONSENT: Scalable self-correction of long reads with multiple sequence alignment

Morisse, P.; Marchet, C.; Limasset, A.; Lecroq, T.; Lefebvre, A.

10.1101/546630 — bioinformatics — Posted on 2019-02-26

290 High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

Merritt, C. R.; Ong, G. T.; Church, S.; Barker, K.; Geiss, G.; Hoang, M.; Jung, J.; Liang, Y.; McKay-Fleisch, J.; Nguyen, K.; Sorg, K.; Sprague, I.; Warren, C.; Warren, S.; Zhou, Z.; Zollinger, D. R.; Dunaway, D. L.; Mills, G. B.; Beechem, J. M.

10.1101/559021 — pathology — Posted on 2019-02-26

291 Non-proliferative adult neurogenesis in neural crest-derived stem cells isolated from human periodontal ligament.

Bueno, C.; Martinez-Morga, M.; Martinez, S.

10.1101/325613 — neuroscience — Posted on 2019-02-26

292 Tracking the emergence of location-based spatial representations

Berens, S. C.; Joensen, B. H.; Horner, A. J.

10.1101/547976 — neuroscience — Posted on 2019-02-26

293 ADHD Symptoms are Associated with the Modular Structure of Intrinsic Brain Networks in a Representative Sample of Healthy Adults

Hilger, K.; Fiebach, C. J.

10.1101/505891 — neuroscience — Posted on 2019-02-26

294 A high-resolution, chromosome-assigned Komodo dragon genome reveals adaptations in the cardiovascular, muscular, and chemosensory systems of monitor lizards

Lind, A.; Lai, Y. Y. Y.; Mostovoy, Y.; Holloway, A. K.; Iannucci, A.; Mak, A. C.; Fondi, M.; Orlandini, V.; Eckalbar, W. L.; Milan, M.; Rovatsos, M.; Kichigin, I. G.; Makunin, A. I.; Pokorna, M.; Altmanova, M.; Trifonov, V.; Schijlen, E.; Kratochvil, L.; Fani, R.; Jessop, T. S.; Patarnello, T.; Hicks, J. W.; Ryder, O. A.; Mendelson, J. R.; Ciofi, C.; Kwok, P.-Y. A.; Pollard, K. S.; Bruneau, B.

10.1101/551978 — genomics — Posted on 2019-02-26

295 A splice donor variant in CCDC189 is associated with asthenospermia in Nordic Red dairy cattle

Iso-Touru, T.; Wurmser, C.; Venhoranta, H.; Hiltpold, M.; Savolainen, T.; Sironen, A.; Fischer, K.; Flisikowski, K.; Fries, R.; Vicente-Carrillo, A.; Alvarez-Rodriguez, M.; Nagy, S.; Mutikainen, M.; Peippo, J.; Taponen, J.; Sahana, G.; Guldbrandtsen, B.; Simonen, H.; Rodriguez-Martinez, H.; Andersson, M.; Pausch, H.

10.1101/472282 — genomics — Posted on 2019-02-26

296 Fitness dependence of the fixation-time distribution for evolutionary dynamics on graphs

Hathcock, D.; Strogatz, S. H.

10.1101/496380 — evolutionary biology — Posted on 2019-02-26

297 Erosion of phylogenetic diversity in Neotropical bat assemblages: findings from a whole-ecosystem fragmentation experiment

Aninta, S. G.; Rocha, R.; Lopez-Baucells, A.; Meyer, C. F. J.

10.1101/534057 — ecology — Posted on 2019-02-26

298 Competitive Inhibitors of Ras Effector Binding

Wiechmann, S.; Maisonneuve, P.; Grebbin, B. M.; Hoffmeister, M.; Kaulich, M.; Clevers, H.; Rajalingam, K.; Kurinov, I.; Farin, H. F.; Sicheri, F.; Ernst, A.

10.1101/548750 — cancer biology — Posted on 2019-02-26

299 Cancerous phenotypes associated with hypoxia-inducible factors are not influenced by the volatile anesthetic isoflurane in renal cell carcinoma

Sumi, C.; Matsuo, Y.; Kusunoki, M.; Shoji, T.; Uba, T.; Iwai, T.; Bono, H.; Hirota, K.

10.1101/375311 — cancer biology — Posted on 2019-02-26

300 PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer

Santiago-Gomez, A.; Dragoni, I.; NicAmhlaoibh, R.; Trivier, E.; Sabin, V.; Simoes, B. M.; Gee, J. M.; Sims, A. H.; Howell, S. J.; Clarke, R. B.

10.1101/558528 — cancer biology — Posted on 2019-02-26

301 A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells

Mboge, M. Y.; Chen, Z.; Khokhar, D.; Wolff, A.; Ai, L.; Heldermon, C. D.; Boxdag, M.; Carta, F.; Supuran, C. T.; Brown, K. D.; Mckenna, R.; Frost, C. J.; Frost, S. C.

10.1101/505644 — cancer biology — Posted on 2019-02-26

302 Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM

Righetto, R.; Biyani, N.; Kowal, J.; Chami, M.; Stahlberg, H.

10.1101/488403 — biophysics — Posted on 2019-02-26

303 Empowering the annotation and discovery of structured RNAs with scalable and accessible integrative clustering

Miladi, M.; Sokhoyan, E.; Houwaart, T.; Heyne, S.; Costa, F.; Gruening, B.; Backofen, R.

10.1101/550335 — bioinformatics — Posted on 2019-02-26

304 Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits

Wheeler, H. E.; Ploch, S.; Barbeira, A. N.; Bonazzola, R.; Andaleon, A.; Siahpirani, A. F.; Saha, A.; Battle, A.; Roy, S.; Im, H. K.

10.1101/471748 — genetics — Posted on 2019-02-26

305 Bacterial defiance as a form of prodrug failure

Holt, B. A.; Kwong, G. A.

10.1101/556951 — bioengineering — Posted on 2019-02-26

306 Synthetic gene circuits enable systems-level biosensor discovery at the host-microbe interface

Naydich, A. D.; Nangle, S. N.; Bues, J. J.; Trivedi, D.; Nissar, N.; Inniss, M. C.; Niederhuber, M. J.; Way, J. C.; Silver, P. A.; Riglar, D. T.

10.1101/557934 — synthetic biology — Posted on 2019-02-26

307 Comparative architectures of direct and social genetic effects from the genome-wide association study of 170 phenotypes in laboratory mice

Baud, A.; Casale, F. P.; Nicod, J.; Stegle, O.

10.1101/302349 — genetics — Posted on 2019-02-26

308 Parasite intensity is driven by temperature in a wild bird

Mennerat, A.; Charmantier, A.; Hurtrez-Bousses, S.; Perret, P.; Lambrechts, M. M.

10.1101/323311 — ecology — Posted on 2019-02-26

309 Kinetochore protein depletion underlies cytokinesis failure and somatic polyploidization in the moss Physcomitrella patens

Kozgunova, E.; Nishina, M.; Goshima, G.

10.1101/438648 — cell biology — Posted on 2019-02-26

310 Stability-normalised walking speed: a new approach for human gait perturbation research

McCrum, C.; Willems, P.; Karamanidis, K.; Meijer, K.

10.1101/314757 — bioengineering — Posted on 2019-02-26

311 Rare non-synonymous germline mutations systematically define the risk of triple negative breast cancer

Yang, M.; Fan, F. Y.; Wu, Z.-Y.; Feng, Z.; Zhang, Q.; Han, S.; Li, X.; Zhu, T.; Cheng, M.; Xu, J.; Yang, C.; Gao, H.; Zhang, C.; Tan, G.; Zhang, M. Q.; Song, Y.-Q.; Niu, G.; Wang, K.

10.1101/302398 — cancer biology — Posted on 2019-02-26

312 Endothelial specific PER2 at the crossroads of light elicited circadian amplitude enhancement as novel cardioprotective strategy and transcriptional regulation of HIF1A-dependent metabolic adaptation to myocardial ischemia

Oyama, Y.; Bartman, C. M.; Bonnie, S.; Lee, J. S.; Walker, L. A.; Han, J.; Borchers, C. H.; Buttrick, P. M.; Clendenen, N.; Colgan, S. P.; Eckle, T.

10.1101/561340 — cell biology — Posted on 2019-02-26

313 Modeling cell shape diversity arising from complex Rho GTPase dynamics

Zmurchok, C.; Holmes, W. R.

10.1101/561373 — biophysics — Posted on 2019-02-26

314 LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Ast, J.; Arvaniti, A.; Fine, N. H. F.; Nasteska, D.; Ashford, F. B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B. J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A. K.; D'Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D. J.

10.1101/557132 — cell biology — Posted on 2019-02-26

315 The kinesin-like protein Pavarotti functions non-canonically to regulate actin dynamics

Nakamura, M.; Verboon, J. M.; Prentiss, C. L.; Parkhurst, S. M.

10.1101/561936 — cell biology — Posted on 2019-02-26

316 DeepSV: Accurate calling of genomic deletions from high throughput sequencing data using deep convolutional neural network

Cai, L.; Wu, Y.; Gao, J.

10.1101/561357 — bioinformatics — Posted on 2019-02-26

317 AutoCryoPicker: An Unsupervised Learning Approach for Fully Automated Single Particle Picking in Cryo-EM Images

Al-Azzawi, A.; Ouadou, A.; Tanner, J.; Cheng, J.

10.1101/561928 — bioinformatics — Posted on 2019-02-26

318 Understanding the Athena SWAN award scheme for gender equality as a complex social intervention in a complex system: analysis of Silver award action plans in a comparative European perspective

Kalpazidou Schmidt, E.; Ovseiko, P. V.; Henderson, L. R.; Kiparoglou, V.

10.1101/555482 — scientific communication and education — Posted on 2019-02-26

319 An oomycete RXLR effector triggers antagonistic plant hormone crosstalk to suppress host immunity

Anderson, R.; Deb, D.; Withers, J.; He, S. Y.; McDowell, J.

10.1101/561605 — plant biology — Posted on 2019-02-26

320 xiView: A common platform for the downstream analysis of Crosslinking Mass Spectrometry data

Graham, M. J.; Combe, C.; Kolbowski, L.; Rappsilber, J.

10.1101/561829 — molecular biology — Posted on 2019-02-26

321 Synthetic Dual-Acting Small-Molecule Inhibitors That Target Mycobacterial DNA Replication

Singh, M.; Ilic, S.; Tam, B.; Ben-Ishay, Y.; Dewangan, R. P.; Sherf, D.; Pappo, D.; Akabayov, B.

10.1101/561506 — biochemistry — Posted on 2019-02-26

322 Methyl-CpG binding domain 2 (Mbd2) is an Epigenetic Regulator of Autism-Risk Genes and Cognition

Lax, E.; Do Carmo, S.; Enuka, Y.; Sapozhnikov, D. M.; Welikovitch, L. A.; Mahmood, N.; Rabbani, S. A.; Wang, L.; Hancock, W. W.; Yarden, Y.; Szyf, M.

10.1101/247197 — neuroscience — Posted on 2019-02-26

323 Integrated approaches to identifying cryptic bat species in areas of high endemism: the case of Rhinolophus andamanensis in the Andaman Islands

Srinivasulu, C.; Srinivasulu, A.; Srinivasulu, B.; Jones, G.

10.1101/561860 — zoology — Posted on 2019-02-26

324 Suppression of GABAergic transmission in the spinal dorsal horn induces pain-related behavior in a chicken model of spina bifida

KHAN, S. I.; Nabeka, H.; Islam, F.; Shimokawa, T.; Saito, S.; Tachibana, T.; Matsuda, S.

10.1101/561852 — neuroscience — Posted on 2019-02-26

325 Do combinations of clinical parameters related to caries activity status predict progression more accurately than individual parameters?

Floriano, I.; Matos, R.; Mattos-Silveira, J.; Rocha, E. S.; Ekstrand, K. R.; Mendes, F. M.; Braga, M. M.

10.1101/561878 — epidemiology — Posted on 2019-02-26

326 Detecting space-time clusters of dengue fever in Panama after adjusting for vector surveillance data

Whiteman, A.; Desjardins, M. R.; Eskildsen, G. A.; Loaiza, J. R.

10.1101/561902 — epidemiology — Posted on 2019-02-26

327 Quantitative investigation of factors relevant to the T cell spot test for tuberculosis infection in active tuberculosis

Li, K.; Yang, C.; Jiang, Z.; Liu, S.; Liu, J.; Fan, C.; Li, T.; Dong, X.

10.1101/561886 — epidemiology — Posted on 2019-02-26

328 Single cell q-PCR derived expression profiles of identified sensory neurons

Adelman, P.; Baumbauer, K.; Friedman, R.; Shah, M.; Wright, M.; Young, E.; Jankowski, M. P.; Albers, K. M.; Koerber, H. R.

10.1101/560672 — neuroscience — Posted on 2019-02-26

329 Carnivore endozoochory of a dry fruited tree can benefit quarry passive restoration

Salgueiro, V.; Silva, C.; Eufrazio, S.; Salgueiro, P.; Vaz, P. G.

10.1101/561142 — ecology — Posted on 2019-02-26

330 Divisively normalized integration of multisensory error information develops motor memories specific to vision and proprioception

Hayashi, T.; Kato, Y.; Nozaki, D.

10.1101/561332 — neuroscience — Posted on 2019-02-26

331 Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from south and southeast Asia.

Wyres, K. L.; Nguyen, T. N.; Lam, M. M.; Judd, L. M.; van Vinh Chau, N.; Dance, D. A.; Ip, M.; Karkey, A.; Ling, C. L.; Miliya, T.; Newton, P.; Nguyen, L.; Sengduangphachanh, A.; Turner, P.; Veeraraghavan, B.; Voong Vinh, P.; Vongsouvath, M.; Thomson, N. R.; Baker, S.; Holt, K. E.

10.1101/557785 — microbiology — Posted on 2019-02-26

332 A Signaling Network based Computational Model to Uncover Loop as the Novel Molecular Mechanisms for Medulloblastoma

Xu, J.; Li, F.

10.1101/561076 — bioinformatics — Posted on 2019-02-26

333 Blood metabolome signature predicts gut microbiome α-diversity in health and disease

Wilmanski, T.; Rappaport, N.; Earls, J. C.; Magis, A. T.; Manor, O.; Lovejoy, J.; Omenn, G. S.; Hood, L.; Gibbons, S.; Price, N. D.

10.1101/561209 — bioinformatics — Posted on 2019-02-26

334 Rapid breath analysis for acute respiratory distress syndrome diagnostics using a portable 2-dimensional gas chromatography device

Zhou, M.; Sharma, R.; Zhu, H.; Li, J.; Wang, S.; Bisco, E.; Massey, J.; Pennington, A.; Sjoding, M.; Dickson, R. P.; Park, P.; Hyzy, R.; Napolitano, L.; Ward, K. R.; Fan, X.

10.1101/560888 — bioengineering — Posted on 2019-02-26

335 Oncogenic Mutations in Histologically Normal Endometrium: The New Normal?

Lac, V.; Nazeran, T. M.; Tessier-Cloutier, B.; Aguirre-Hernandez, R.; Albert, A.; Lum, A.; Khattra, J.; Praetorius, T.; Mason, M.; Chiu, D.; Köbel, M.; Yong, P. J.; Gilks, B. C.; Anglesio, M. S.; Huntsman, D. G.

10.1101/561050 — pathology — Posted on 2019-02-26

336 Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

Hillary, R. F.; McCartney, D. L.; Harris, S. E.; Stevenson, A. J.; Seeboth, A.; Zhang, Q.; Liewald, D. C.; Evans, K. L.; Ritchie, C. W.; Tucker-Drob, E. M.; Wray, N. R.; McRae, A. F.; Visscher, P. M.; Deary, I. J.; Marioni, R. E.

10.1101/558940 — neuroscience — Posted on 2019-02-26

337 Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

Han, L. K.; Dinga, R.; Hahn, T.; Ching, C.; Eyler, L.; Aftanas, L.; Aghajani, M.; Aleman, A.; Baune, B.; Berger, K.; Brak, I.; Busatto Filho, G.; Carballedo, A.; Connolly, C.; Couvy-Duchesne, B.; Cullen, K.; Dannlowski, U.; Davey, C.; Dima, D.; Duran, F.; Enneking, V.; Filimonova, E.; Frenzel, S.; Frodl, T.; Fu, C.; Godlewska, B.; Gotlib, I.; Grabe, H.; Groenewold, N.; Grotegerd, D.; Gruber, O.; Hall, G.; Harrison, B.; Hatton, S.; Hermesdorf, M.; Hickie, I.; Ho, T.; Hosten, N.; Jansen, A.; Kahler, C.; Kircher, T.; Klimes-Dougan, B.; Kramer, B.; Krug, A.; Lagopoulos, J.; Leenings, R.; MacMaster

10.1101/560623 — neuroscience — Posted on 2019-02-26

338 Pharmacogenomics, biomarker network and allele frequencies in colorectal cancer

Lopez-Cortes, A.; Paz-y-Mino, C.; Guerrero, S.; Jaramillo-Koupermann, G.; Intriago-Baldeon, D.; Garcia, J.; Patricia, G.; Armendariz-Castillo, I.; Leone, P. E.; Quinones, L. A.; Cayun, J. P.; Soria, N.

10.1101/561316 — genomics — Posted on 2019-02-26

339 A Rab11-GEF Parcas recruits Rab11 onto recycling endosomes for rhodopsin transport in Drosophila photoreceptors

Otsuka, Y.; Satoh, T.; Nakayama, N.; Inaba, R.; Satoh, A. K.

10.1101/561563 — cell biology — Posted on 2019-02-26

340 Transcriptomically-guided mesendoderm induction of human pluripotent stem cells using a systematically defined culture scheme

Carpenedo, R. L.; Kwon, S. Y.; Tanner, R. M.; Yockell-Lelievre, J.; Choey, C.; Dore, C.; Ho, M.; Stewart, D. J.; Perkins, T. J.; Stanford, W. L.

10.1101/561068 — bioengineering — Posted on 2019-02-26

341 Flv1-4 proteins function in versatile combinations in O2 photoreduction in cyanobacteria

Santana Sanchez, A. I.; Solymosi, D.; Mustila, H.; Bersanini, L.; Aro, E.-M.; Allahverdiyeva-Rinne, Y.

10.1101/561456 — biochemistry — Posted on 2019-02-26

342 Asparagine endopeptidase cleaves tau at N167 after uptake into microglia

Behrendt, A.; Bichmann, M.; Ercan-Herbst, E.; Haberkant, P.; Schoendorf, D. C.; Wolf, M.; Fahim, S. A.; Murolo, E.; Ehrnhoefer, D.

10.1101/560110 — neuroscience — Posted on 2019-02-26

343 Pair-wise Comparison Analysis for Multiple Pool-sep: an efficient method identified anthocyanin biosynthesis genes in rice pericarp

Yang, X.; Xia, X.; Zhang, Z.; Nong, B.; Zeng, Y.; Wu, Y.; Xiong, F.; Zhang, Y.; Liang, H.; Pan, Y.; Dai, G.; Deng, G.; Li, D.

10.1101/561258 — molecular biology — Posted on 2019-02-26

344 Vancomycin Relieves Mycophenolate Mofetil-Induced Gastrointestinal Toxicity by Eliminating Gut Bacterial β-Glucuronidase Activity

Taylor, M. R.; Flannigan, K. L.; Rahim, H.; Mohamud, A.; Lewis, I. A.; Hirota, S. A.; Greenway, S. C.

10.1101/561274 — microbiology — Posted on 2019-02-26

345 Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer

Wang, G.; Yang, Q.; Li, M.; Zhang, Y.; Cai, Y.; Liang, X.; Fu, Y.; Xiao, Z.; Zhou, M.; Xie, Z.; Huang, H.; Huang, Y.; Chen, Y.; He, Q.; Peng, F.; Chen, Z.

10.1101/561555 — cancer biology — Posted on 2019-02-26

346 Title - Taxonomic survey of Anadenobolus monilicornis gut microbiota via shotgun nanopore sequencing

Geli-Cruz, O.; Cafaro, M. J.; Santos-Flores, C. J.; Ropelewski, A. J.; Van Dam, A. R.

10.1101/560755 — genomics — Posted on 2019-02-26

347 A positively selected, common, missense variant in FBN1 confers a 2.2 centimeter reduction of height in the Peruvian population

Asgari, S.; Luo, Y.; Belbin, G. M.; Bartell, E.; Roger, R.; Slowikowski, K.; Contreras, C.; Yataco, R.; Galea, J. T.; Jimenez, J.; Coit, J. M.; Farronay, C.; Nazarian, R. M.; O Connor, T. D.; Dietz, H. C.; Hirschhorn, J.; Guio, H.; Lecca, L.; Kenny, E. E.; Freeman, E.; Murray, M. B.; Raychaudhuri, S.

10.1101/561241 — genomics — Posted on 2019-02-26

348 Prevalence of sleep-disordered breathing and associations with malocclusion in children

Lyra, M.; Aguiar, D.; Paiva, M.; Arnaud, M.; Filho, A. A.; Rosenblatt, A.; Therese Innes, N. P.; Heimer, M. V.

10.1101/560722 — epidemiology — Posted on 2019-02-26

349 Absolute quantification of cohesin, CTCF and their regulators in human cells

10.1101/560425 — cell biology — Posted on 2019-02-26

350 The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis

Koyano, T.; Namba, M.; Kobayashi, T.; Nakakuni, K.; Nakano, D.; Fukushima, M.; Nishiyama, A.; Matsuyama, M.

10.1101/560078 — cell biology — Posted on 2019-02-26

351 Highly Efficient Repair of the ΔF508 Mutation in Airway Stem Cells of Cystic Fibrosis Patients with Functional Rescue of the Differentiated Epithelia

Vaidyanathan, S.; Salahudeen, A. A.; Sellers, Z. M.; Bravo, D. T.; Choi, S. S.; Batish, A.; Le, W.; De La O, S.; Kaushik, M. P.; Galper, N.; Lee, C. M.; Bao, G.; Chang, E. H.; Wine, J. J.; Milla, C. E.; Desai, T. J.; Nayak, J. V.; Kuo, C. J.; Porteus, M. H.

10.1101/561183 — bioengineering — Posted on 2019-02-26

352 Undiagnosed and diagnosed hypertension in a community setting at Hosanna town: Uncovering the burden

Dereje, N.; Earsido, A.; Abebe, A.; Temam, L.

10.1101/560748 — epidemiology — Posted on 2019-02-26

353 PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation

Rutgers, M.; Bach, F.; Vonk, L.; van Rijen, M.; Akrum, V.; van Boxtel, A.; Dhert, W.; Creemers, L.

10.1101/560771 — cell biology — Posted on 2019-02-26

354 Triple Arginines as Molecular Determinants for Pentameric Assembly of the Intracellular Domain of 5-HT3A Receptors

Pandhare, A.; Pirayesh, E.; Stuebler, A. G.; Jansen, M.

10.1101/561282 — biophysics — Posted on 2019-02-26

355 Nanoparticle-mediated transformation expands horizon of organism engineering

French, K. E.

10.1101/559252 — synthetic biology — Posted on 2019-02-25

356 Factors that influence scientific productivity from different countries: A causal approach through multiple regression using panel data

Lancho-Barrantes, B. S.; Ceballos, H. G.; Cantu-Ortiz, F. J.

10.1101/558254 — scientific communication and education — Posted on 2019-02-25

357 Sox6: A new modulator of renin expression during physiological conditions

Saleem, M.; Hodgkinson, C. P.; Contreras, E. W.; Xiao, L.; Gimenez-Bastida, J. A.; Foss, J.; Payne, A. J.; Mirotsou, M.; Gama, V.; Dzau, V. J.; Gomez, J. A.

10.1101/556118 — physiology — Posted on 2019-02-25

358 Distinct Regulaton of Bioenergetics and Translation by Gp I mGluRs and NMDARs

Ghosh Dastidar, S.; Chakraborty, S.; Chattarji, S.; Bhattacharya, A.; Muddashetty, R.

10.1101/552638 — neuroscience — Posted on 2019-02-25

359 Fingerprinting Adiposity and Metabolic Function in the Brains of Overweight and Obese Humans

Farruggia, M. C.; van Kooten, M. J.; Burke, M. V.; Scheinost, D.; Constable, R. T.; Small, D. M.

10.1101/540997 — neuroscience — Posted on 2019-02-25

360 TIMP-1 attenuates the development of cutaneous inflammation-induced hypersensitivity

Knight, B. E.; Kozlowski, N.; Havelin, J.; King, T.; Crocker, S. J.; Young, E. E.; Baumbauer, K.

10.1101/540724 — neuroscience — Posted on 2019-02-25

361 DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute

Hegge, J. W.; Swarts, D. C.; Chandradoss, S. D.; Cui, T. J.; Kneppers, J.; Jinek, M.; Joo, C.; van der Oost, J.

10.1101/534206 — molecular biology — Posted on 2019-02-25

362 Supervised classification enables rapid annotation of cell atlases

Pliner, H. A.; Shendure, J.; Trapnell, C.

10.1101/538652 — genomics — Posted on 2019-02-25

363 Serial horizontal transfer of vitamin-biosynthetic genes enables the establishment of new nutritional symbionts in aphids' di-symbiotic systems

Manzano-Marin, A.; Coeur d'acier, A.; Clamens, A.-L.; Orvain, C.; Cruaud, C.; Barbe, V.; Jousselin, E.

10.1101/556274 — genomics — Posted on 2019-02-25

364 Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

Fougner, C.; Bergholtz, H.; Kuiper, R.; Norum, J. H.; Sorlie, T.

10.1101/557298 — genomics — Posted on 2019-02-25

365 Adaptive walks on high-dimensional fitness landscapes and seascapes with distance-dependent statistics

Agarwala, A.; Fisher, D. S.

10.1101/435669 — evolutionary biology — Posted on 2019-02-25

366 Identification of frequent activating HER2 mutations in primary canine pulmonary adenocarcinoma

Lorch, G.; Sivaprakasam, K.; Zismann, V.; Perdigones, N.; Contente-Cuomo, T.; Nazareno, A.; Facista, S.; Wong, S.; Drenner, K.; Liang, W. S.; Amann, J. M.; Sinicropi-Yao, S. L.; Koenig, M. J.; La Perle, K.; Whitsett, T. G.; Murtaza, M.; Trent, J.; Carbone, D. P.; Hendricks, W. P. D.

10.1101/528182 — cancer biology — Posted on 2019-02-25

367 Increased Replication Rates of Dissimilatory Nitrogen-Reducing Bacteria Leads to Decreased Anammox Reactor Performance

Keren, R.; Lawrence, J.; Zhuang, W.-Q.; Jenkins, D.; Banfield, J. F.; Alvarez-Cohen, L.; Zhou, L.; Yu, K.

10.1101/534925 — microbiology — Posted on 2019-02-25

368 Searching the optimal folding routes of a Complex Lasso protein

Perego, C.; Potestio, R.

10.1101/507079 — biophysics — Posted on 2019-02-25

369 Surrogate R-spondins for tissue-specific potentiation of Wnt signaling

Luca, V. C.; Miao, Y.; Li, X.; Hollander, M. J.; Kuo, C. J.; Garcia, K. C.

10.1101/487223 — molecular biology — Posted on 2019-02-25

370 OxyR senses reactive sulfane sulfur and activates genes for its removal in Escherichia coli

Hou, N.; Yan, Z.; Fan, K.; LI, H.; Zhao, R.; Xia, Y.; Liu, H.; Xun, L.

10.1101/561019 — microbiology — Posted on 2019-02-25

371 Leaf Variegation and Impaired Chloroplast Development Caused by a Truncated CCT Domain gene in albostrians Barley

Li, M.; Hensel, G.; Mascher, M.; Melzer, M.; Budhagatapalli, N.; Rutten, T.; Himmelbach, A.; Beier, S.; Korzun, V.; Kumlehn, J.; Boerner, T.; Stein, N.

10.1101/560797 — genetics — Posted on 2019-02-25

372 Range-wide spatial mapping reveals convergent character displacement of bird song

Kirschel, A. N. G.; Seddon, N.; Tobias, J.

10.1101/560276 — evolutionary biology — Posted on 2019-02-25

373 BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cell lines

Janssen, S. M.; Moscona, R.; Elchebly, M.; Papadakis, A. I.; Redpath, M.; Wang, H.; Rubin, E.; van Kempen, L. C.; Spatz, A.

10.1101/560474 — cancer biology — Posted on 2019-02-25

374 Can one trust kinetic and thermodynamic observables from biased metadynamics simulations: detailed quantitative benchmarks on millimolar drug fragment dissociation

Pramanik, D.; Smith, Z.; Kells, A.; Tiwary, P.

10.1101/558601 — biochemistry — Posted on 2019-02-25

375 Partial coherence and frustration in self-organizing spherical grids

Stella, F.; Urdapilleta, E.; Treves, A.

10.1101/560318 — neuroscience — Posted on 2019-02-25

376 Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

Noordam, R.; Bos, M. M.; Wang, H.; Winkler, T. W.; Bentley, A. R.; Kilpeläinen, T.; de Vries, P. S.; Sung, Y. J.; Schwander, K.; Cabe, B. E.; Manning, A.; Aschard, H.; Brown, M. R.; Chen, H.; Franceschini, N.; Musani, S. K.; Richard, M.; Vojinovic, D.; Aslibekyan, S.; Bartz, T. M.; de las Fuentes, L.; Feitosa, M.; Horimoto, A. R.; Ilkov, M.; Kho, M.; Kraja, A.; Li, C.; Lim, E.; Liu, Y.; Mook-Kanamori, D. O.; Rankinen, T.; Tajuddin, S. M.; van der Spek, A.; Wang, Z.; Marten, J.; Laville, V.; Alver, M.; Evangelou, E.; Graff, M. E.; He, M.; Kühnel, B.; Lyytikäinen, L.-P.; Marques-Vidal, P.; No

10.1101/559393 — genomics — Posted on 2019-02-25

377 Mode and tempo of microsatellite length change in a malaria parasite mutation accumulation experiment

McDew-White, M.; Li, X.; Nkhoma, S. C.; Nair, S.; Cheeseman, I.; Anderson, T. J. C.

10.1101/560516 — evolutionary biology — Posted on 2019-02-25

378 Interdependent Phenotypic and Biogeographic Evolution Driven by Biotic Interactions

Quintero, I.; Landis, M. J.

10.1101/560912 — evolutionary biology — Posted on 2019-02-25

379 Reconstruction of clone- and haplotype-specific cancer genome karyotypes from bulk tumor samples

Aganezov, S.; Raphael, B. J.

10.1101/560839 — cancer biology — Posted on 2019-02-25

380 Differences in resources use lead to coexistence of seed-transmitted microbial populations

Torres-Cortes, G.; Garcia, B. J.; Compant, S.; Rezki, S.; Jones, P.; Preveaux, A.; Briand, M.; Roulet, A.; Bouchez, O.; Jacobson, D.; Barret, M.

10.1101/560367 — plant biology — Posted on 2019-02-25

381 Cardiac Metabolic Limitations Contribute to Diminished Performance of the Heart in Aging

Gao, X.; Jakovljevic, D. G.; Beard, D. A.

10.1101/560649 — physiology — Posted on 2019-02-25

382 Head motion predictability explains activity-dependent suppression of vestibular balance control

Dietrich, H.; Heidger, F.; Schniepp, R.; MacNeilage, P.; Glasauer, S.; Wuehr, M.

10.1101/560664 — physiology — Posted on 2019-02-25

383 Gorilla in our Midst: An online behavioral experiment builder

Anwyl-Irvine, A.; Massonnie, J.; Flitton, A.; Kirkham, N.; Evershed, J.

10.1101/438242 — neuroscience — Posted on 2019-02-25

384 Intra-mitochondrial protein degradationalleviates alpha-synuclein seeding and Abeta 42 aggregation

Lautenschlaeger, J.; Wagner-Valladolid, S.; Stephens, A. D.; Fernandez-Villegas, A.; Hockings, C.; Mishra, A.; Manton, J. D.; Fantham, M. J.; Lu, M.; Rees, E. J.; Kaminski, C. F.; Kaminski Schierle, G. S.

10.1101/561134 — neuroscience — Posted on 2019-02-25

385 Contributions of Low- and High-Frequency Sensorineural Hearing Deficits to Speech Intelligibility in Noise

Verhulst, S.; Warzybok, A.

10.1101/358127 — neuroscience — Posted on 2019-02-25

386 Single Trial Decoding of Scalp EEG Under Natural Conditions

Tuckute, G.; Hansen, S. T.; Pedersen, N.; Steenstrup, D.; Hansen, L. K.

10.1101/481630 — neuroscience — Posted on 2019-02-25

387 Task-evoked activity quenches neural correlations and variability in large-scale brain systems

Ito, T.; Brincat, S. L.; Siegel, M.; Mill, R. D.; He, B. J.; Miller, E. K.; Rotstein, H. G.; Cole, M. W.

10.1101/560730 — neuroscience — Posted on 2019-02-25

388 Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

S, S.; Amaral, P.; Engstrom, P. G.; Robson, S. C.; Nielsen, M. L.; Kouzarides, T.; Castelo-Branco, G.

10.1101/560383 — molecular biology — Posted on 2019-02-25

389 Bacterial Cyclopropane Fatty Acid Synthase mRNA is targeted by activating and repressing small RNAs

Bianco, C. M.; Froehlich, K.; Vanderpool, C. K.

10.1101/271551 — microbiology — Posted on 2019-02-25

390 Samovar: Single-sample mosaic SNV calling with linked reads

Darby, C. A.; Fitch, J. R.; Brennan, P. J.; Kelly, B. J.; Bir, N.; Magrini, V.; Leonard, J.; Cottrell, C. E.; Gastier-Foster, J. M.; Wilson, R. K.; Mardis, E. R.; White, P.; Langmead, B.; Schatz, M. C.

10.1101/560532 — genomics — Posted on 2019-02-25

391 A Novel Integrative Multiomics Method Reveals a Hypoxia-Related Subgroup of Breast Cancer with Significantly Decreased Survival

Pouryahya, M.; Oh, J. H.; Javanmard, P.; Mathews, J.; Belkhatir, Z.; Deasy, J.; Tannenbaum, A. R.

10.1101/558700 — genomics — Posted on 2019-02-25

392 The impact of protein architecture on adaptive evolution

Moutinho, A. F.; Fontes Trancoso, F.; Yann Dutheil, J.

10.1101/560185 — evolutionary biology — Posted on 2019-02-25

393 ChIP-GSM: cell type-specific cis-regulatory module inference for active regulatory element prediction

Chen, X.

10.1101/560862 — bioinformatics — Posted on 2019-02-25

394 BICORN: An R package for integrative inference of de novo cis-regulatory modules

Chen, X.

10.1101/560557 — bioinformatics — Posted on 2019-02-25

395 Identification of new inhibitors of the Toxoplasma gondii by using in-silico drug repurposing

Kadkhodamohammadi, M.; Jaberi, M.; Babaei Akerdi, R.; Ahmadi, A.; Aliyar, M.

10.1101/560284 — bioinformatics — Posted on 2019-02-25

396 SCINA: Semi-Supervised Analysis of Single Cells in silico

Zhang, Z.; Luo, D.; Zhong, X.; Choi, J. H.; Ma, Y.; Mahrt, E.; Guo, W.; Stawiski, E. W.; Wang, S.; Modrusan, Z.; Seshagiri, S.; Kapur, P.; Wang, X.; Hon, G. C.; Brugarolas, J.; Wang, T.

10.1101/559872 — bioinformatics — Posted on 2019-02-25

397 AngularQA: Protein Model Quality Assessment with LSTM Networks

Conover, M.; Staples, M.; Si, D.; Sun, M.; Cao, R.

10.1101/560995 — bioinformatics — Posted on 2019-02-25

398 An omentum-inspired 3D PEG hydrogel for identifying ECM drivers of drug resistant ovarian cancer

Brooks, E. A.; Gencoglu, M. F.; Corbett, D. C.; Stevens, K. R.; Peyton, S.

10.1101/560482 — bioengineering — Posted on 2019-02-25

399 Defining the neural correlates of spontaneous theory of mind (ToM): An fMRI mega-analytic investigation

Boccadoro, S.; Cracco, E.; Hudson, A.; Bardi, L.; Nijhof, A.; Wiersema, J. R.; Brass, M.; Mueller, S.

10.1101/560953 — neuroscience — Posted on 2019-02-25

400 Single AAV-mediated scarless genome editing in dysfunctional retinal neurons mediates robust visual restoration in mice

NISHIGUCHI, K. M.; Fujita, K.; Katayama, S.; Nakazawa, T.

10.1101/552653 — bioengineering — Posted on 2019-02-25

401 Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex

Huber, L.; Finn, E. S.; Handwerker, D. A.; Boenstrup, M.; Glen, D.; Kashyap, S.; Ivanov, D.; Petridou, N.; Marrett, S.; Goense, J.; Poser, B.; Bandettini, P. A.

10.1101/457002 — neuroscience — Posted on 2019-02-25

402 From serial to parallel: predicting synchronous firing of large neural populations from sequential recordings

Sorochynskyi, O.; Deny, S.; Marre, O.; Ferrari, U.

10.1101/560656 — neuroscience — Posted on 2019-02-25

403 Increased synaptic facilitation and exploratory behavior in mice lacking the presynaptic protein Mover

Viotti, J. S.; Ott, F. W.; Schleicher, E. M.; Wagner, J. M.; Bouter, Y.; Bayer, T. A.; Dresbach, T.

10.1101/560896 — neuroscience — Posted on 2019-02-25

404 Avant-garde assembly-line biosynthesis expands diversity of cyclic lipodepsipeptide products

Zhang, J. J.; Tang, X.; Huan, T.; Ross, A. C.; Moore, B. S.

10.1101/560987 — molecular biology — Posted on 2019-02-25

405 Selective culture enrichment and sequencing of faeces to enhance detection of antimicrobial resistance genes

Peto, L.; Fawcett, N. J.; Crook, D. W.; Peto, T. E.; Llewelyn, M. J.; Walker, A. S.

10.1101/560292 — microbiology — Posted on 2019-02-25

406 Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

Hofer, E.; Roshchupkin, G. V.; Adams, H.; Knol, M.; Lin, H.; Li, S.; Zare, H.; Ahmad, S.; Armstrong, N.; Satizabal, C.; Bernard, M.; Bis, J.; Gillespie, N.; Luciano, M.; Mishra, A.; Scholz, M.; Teumer, A.; Xia, R.; Jian, X.; Mosley, T.; Saba, Y.; Pirpamer, L.; Seiler, S.; Becker, J.; Carmichael, O.; Rotter, J.; Psaty, B.; Lopez, O.; Amin, N.; Lee, S.; Yang, Q.; Himali, J.; Maillard, P.; Beiser, A.; DeCarli, C.; Karama, S.; Lewis, L.; Bastin, M.; Harris, M.; Deary, I.; Witte, V.; Beyer, F.; Loeffler, M.; Mather, K.; Schofield, P.; Thalamuthu, A.; Kwok, J.; Wright, M.; Ames, D.; Trollor, J.; Jia

10.1101/409649 — genetics — Posted on 2019-02-25

407 A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target

Gregson, C. L.; Bergen, D.; Leo, P.; Sessions, R. B.; Wheeler, L.; Hartley, A.; Youlten, S.; Croucher, P. I.; McInerney-Leo, A. M.; Fraser, W.; Tang, J. C.; Anderson, L.; Marshall, M.; Sergot, L.; Paternoster, L.; Davey Smith, G.; The AOGC Consortium, ; Brown, M. A.; Hammond, C.; Kemp, J. P.; Tobias, J. H.; Duncan, E. L.

10.1101/560565 — genetics — Posted on 2019-02-25

408 Computational complexity as an ultimate constraint on evolution

Kaznatcheev, A.

10.1101/187682 — evolutionary biology — Posted on 2019-02-25

409 Comparative analyses of phenotypic sequences using phylogenetic trees

Caetano, D. S.; Beaulieu, J. M.

10.1101/561167 — evolutionary biology — Posted on 2019-02-25

410 Relocating agriculture could drastically reduce humanity's ecological footprint

Beyer, R. M.; Manica, A.; Rademacher, T. T.

10.1101/488841 — ecology — Posted on 2019-02-25

411 GGA2 and RAB13 promote activity-dependent β1-integrin recycling

Sahgal, P.; Alanko, J.; Icha, J.; Paatero, I.; Hamidi, H.; Arjonen, A.; Pietila, M.; Rokka, A.; Ivaska, J.

10.1101/353086 — cell biology — Posted on 2019-02-25

412 A genome-wide screen for ER autophagy highlights key roles of mitochondrial metabolism and ER- resident UFMylation

Liang, J. R.; Lingeman, E.; Luong, T.; Ahmed, S.; Nguyen, T.; Olzmann, J.; Corn, J. E.

10.1101/561001 — cell biology — Posted on 2019-02-25

413 Epigenetic inheritance of centromere identity in a heterologous system

Roure, V.; Medina-Pritchard, B.; Anselm, E.; Jeyaprakash, A. A.; Heun, P.

10.1101/560391 — cell biology — Posted on 2019-02-25

414 SESCA: Predicting Circular Dichroism Spectra from Protein Molecular Structures

Nagy, G.; Igaev, M.; Hoffmann, S. V.; Jones, N. C.; Grubmuller, H.

10.1101/279752 — biophysics — Posted on 2019-02-25

415 Serial femtosecond X-ray diffraction of HIV-1 Gag MA-IP6 microcrystals at ambient temperature

Ciftci, H. I.; Sierra, R. G.; Yoon, C. H.; Su, Z.; Tateishi, H.; Koga, R.; Kotaro, K.; Yumoto, F.; Senda, T.; Liang, M.; Wakatsuki, S.; Otsuka, M.; Fujita, M.; Demirci, H.

10.1101/561100 — biophysics — Posted on 2019-02-25

416 CALISTA: Clustering And Lineage Inference in Single-Cell Transcriptional Analysis

Papili Gao, N.; Hartmann, T.; Fang, T.; Gunawan, R.

10.1101/257550 — bioinformatics — Posted on 2019-02-25

417 A starless bias in the maximum likelihood phylogenetic methods (and other bias in parameter estimation)

Xia, X.

10.1101/435412 — bioinformatics — Posted on 2019-02-25

418 Nonparametric expression analysis using inferential replicate counts

Zhu, A.; Srivastava, A.; Ibrahim, J. G.; Patro, R.; Love, M. I.

10.1101/561084 — bioinformatics — Posted on 2019-02-25

419 Microporous scaffolds drive assembly and maturation of progenitors into β-cell clusters

Youngblood, R. L.; Sampson, J.; Lebioda, K. L.; Spicer, G. L.; Shea, L. D.

10.1101/560979 — bioengineering — Posted on 2019-02-25

420 Bridging micro and macro: accurate registration of the BigBrain dataset with the MNI PD25 and ICBM152 atlases

Xiao, Y.; Lau, J. C.; Anderson, T.; DeKraker, J.; Collins, D. L.; Peters, T.; Khan, A. R.

10.1101/561118 — bioengineering — Posted on 2019-02-25

421 Build a better mouse task: can an open-source rodent joystick enhance reaching behavior outcomes through improved monitoring of real-time spatiotemporal kinematics?

Belsey, P.; Nicholas, M. A.; Yttri, E. A.

10.1101/560961 — animal behavior and cognition — Posted on 2019-02-25

422 Identification of Microbiota-Induced Gene Expression Changes in the Drosophila melanogaster Head

Keith, S. A.; Eutsey, R.; Lee, H.; Solomon, B.; Oliver, S.; Kingsford, C.; Hiller, N. L.; McCartney, B. M.

10.1101/561043 — microbiology — Posted on 2019-02-25

423 Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination

Hoehn, K. B.; Vander Heiden, J. A.; Zhou, J. Q.; Lunter, G.; Pybus, O. G.; Kleinstein, S. H.

10.1101/558825 — immunology — Posted on 2019-02-25

424 Phylogeographic parallelism: concordance of patterns in closely related species illuminates underlying mechanisms in the historically glaciated Tasmanian landscape

Kreger, K.; Shaban, B.; Wapstra, E.; Burridge, C. P.

10.1101/548446 — evolutionary biology — Posted on 2019-02-25

425 Spt6 is a maintenance factor for centromeric CENP-A

Bobkov, G. O.; Huang, A.; van den Berg, S. J.; Mitra, S.; Anselm, E.; Lazou, V.; Schunter, S.; Federle, R.; Imhof, A.; Lusser, A.; Jansen, L. E.; Heun, P.

10.1101/560300 — cell biology — Posted on 2019-02-25

426 Measuring single cell divisions in human cancers from multi-region sequencing data

Werner, B.; Case, J.; Williams, M. J.; Chkhaidze, K.; Temko, D.; Fernandez-Mateos, J.; Cresswell, G. D.; Nichol, D.; Cross, W.; Spiteri, I.; Huang, W.; Tomlinson, I.; Barnes, C. P.; Graham, T. A.; Sottoriva, A.

10.1101/560243 — cancer biology — Posted on 2019-02-25

427 Classification of RNA backbone conformation into rotamers using 13C' chemical shifts: How far we can go?

Icazatti, A. A.; Loyola, J. M.; Szleifer, I.; Vila, J. A.; Martin, O. A.

10.1101/559302 — biophysics — Posted on 2019-02-25

428 How fast are cells dividing: Probabilistic model of continuous labeling assays

Rode, J.; Goerke, T.; Brusch, L.; Rost, F.

10.1101/550574 — biophysics — Posted on 2019-02-25

429 The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides new insights into the genetics of type 1 diabetes

Ramos-Rodriguez, M.; Raurell-Villa, H.; Colli, M. L.; Alvelos, M. I.; Subirana-Granes, M.; Juan-Mateu, J.; Norris, R.; Turatsinze, J.-V.; Nakayasu, E.; Webb-Robertson, B.-J.; Inshaw, J. R.; Marchetti, P.; Piemonti, L.; Esteller, M.; Todd, J. A.; Metz, T. O.; Eizirik, D. L.; Pasquali, L.

10.1101/560193 — genomics — Posted on 2019-02-25

430 Molecular subtyping and prognostic assessment based on tumor mutation burden in patients with lung adenocarcinomas

Wang, C.; Li, F.; Xie, G.; Qiao, S.; Shi, X.; Deng, J.; Liang, H.; Lin, C.; Zhao, X.; Wu, K.; Zhang, X.

10.1101/553461 — genomics — Posted on 2019-02-25

431 Phylogenetic relationships among the clownfish-hosting sea anemones

Titus, B. M.; Benedict, C.; Laroche, R.; Gusmao, L.; Van Deusen, V.; Chiodo, T.; Meyer, C. P.; Berumen, M. L.; Bartholomew, A.; Yanagi, K.; Reimer, J. D.; Fujii, T.; Daly, M.; Rodriguez, E.

10.1101/560045 — evolutionary biology — Posted on 2019-02-25

432 Strategic Inattention in the Sir Philip Sidney Game

Whitmeyer, M.

10.1101/559955 — evolutionary biology — Posted on 2019-02-25

433 TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer

lee, G. T.; Kim, W. T.; Kwon, Y. S.; Palapattu, G.; Kim, W.-J.; Kim, I. Y.

10.1101/560821 — cancer biology — Posted on 2019-02-25

434 No evidence for kin recognition in a passerine bird.

Lattore, M.; Plaza, M.; Nakagawa, S.; Burke, T.; Schroeder, J.

10.1101/560870 — animal behavior and cognition — Posted on 2019-02-25

435 A direct link between Prss53, hair curvature, and skeletal dysplasia

li, z.; Deng, J.; Song, Y.; Liu, H.; Sui, T.; Chen, M.; Zhang, Y.; Yao, B.; Xu, Y.; Liu, Z.; Lai, L.

10.1101/560847 — genomics — Posted on 2019-02-25

436 Coding Triplets in the Transfer RNA Arm and Their Role in Present and Past tRNA Recognition

Agmon, I.; Fayerverker, I.; Mor, T.

10.1101/559948 — genetics — Posted on 2019-02-25

437 R-DECO: An open-source Matlab based graphical user interface for the detection and correction of R-peaks

Moeyersons, J.; Amoni, M.; Van Huffel, S.; Willems, R.; Varon, C.

10.1101/560706 — bioengineering — Posted on 2019-02-25

438 Controllability of molecular pathways

Wuchty, S.

10.1101/560375 — systems biology — Posted on 2019-02-25

439 Lytic bacteriophage have diverse indirect effects in a synthetic cross-feeding community

Fazzino, L.; Anisman, J.; Chacon, J. M.; Heineman, R. H.; Harcombe, W. R.

10.1101/560037 — systems biology — Posted on 2019-02-25

440 Calcium alginate entrapped Eupatorium adenophorum Sprengel stems powder for Chromium(VI) biosorption in aqueous medium

Aryal, M.

10.1101/560680 — scientific communication and education — Posted on 2019-02-25

441 The effects of combining focus of attention and autonomy support on shot accuracy in the penalty kick

Makaruk, H.; Porter, J. M.; Sadowski, J.; Bodasinska, A.; Zielinski, J.; Niznikowski, T.; Mastalerz, A.

10.1101/560813 — scientific communication and education — Posted on 2019-02-25

442 Regret Induces Rapid Learning from Experience-based Decisions: A Model-based Facial Expression Analysis Approach

Haines, N.; Rass, O.; Shin, Y.-W.; Busemeyer, J. R.; Brown, J. W.; O'Donnell, B. F.; Ahn, W.-Y.

10.1101/560011 — neuroscience — Posted on 2019-02-25

443 Dimensionality Reduction of Diffusion MRI Measures for Improved Tractometry of the Human Brain

Chamberland, M.; Raven, E. P.; Genc, S.; Duffy, K.; Descoteaux, M.; Parker, G. D.; Tax, C. M. W.; Jones, D. K.

10.1101/559351 — neuroscience — Posted on 2019-02-25

444 Grey matter volume changes and corresponding cellular metrics identified in a longitudinal in vivo imaging approach

Asan, L.; Falfan-Melgoza, C.; Weber-Fahr, W.; Beretta, C.; Kuner, T.; Knabbe, J.

10.1101/559765 — neuroscience — Posted on 2019-02-25

445 Hierarchies & Lower Bounds in Theoretical Connectomics

Ramaswamy, V.

10.1101/559260 — neuroscience — Posted on 2019-02-25

446 Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition

Blus, B.; Hashimoto, H.; Seo, H.-S.; Krolak, A.; Debler, E.

10.1101/559005 — molecular biology — Posted on 2019-02-25

447 Modification of T cells function after restoration of spontaneous circulation in a rat model of cardiac arrest

Xing, C.; Chen, Y.; Zhu, X.; Lu, G.; Chen, W.

10.1101/560789 — immunology — Posted on 2019-02-25

448 Mutation Effects on Remote Epitopes of An Autoantigen Decoded with Simulated B-Factors

Pang, Y.-P.; Casal Moura, M.; Thompson, G. E.; Hummel, A. M.; Nelson, D. R.; Jenne, D. E.; Specks, U.

10.1101/559963 — immunology — Posted on 2019-02-25

449 Development and validation of microsatellite markers from de novo transcriptome assembly of eggplant (Solanum melongena L.) and its putative progenitor S. incanum L. cultivars

Tiwari, S. K.; Mishra, P.; Singh, S.; Singh, V. K.; Kashyap, S. P.; Tiwari, K. N.; Singh, M.; Naik, P. S.; Singh, B.

10.1101/560805 — genomics — Posted on 2019-02-25

450 Antibiotic production is organized by a division of labour in Streptomyces

Zhang, Z.; de Barsy, F.; Liem, M.; Liakopoulos, A.; Choi, Y. H.; Claessen, D.; Rozen, D.

10.1101/560136 — evolutionary biology — Posted on 2019-02-25

451 Prevalence of HIV-1 infection among foreign applicant to residency in Shanghai, China, 2005-2016

Qin, J.; Zhou, R.; Xia, J.; Wang, W.; Pan, J.; Pan, J.; Zhou, X.; Zhang, Q.

10.1101/560854 — epidemiology — Posted on 2019-02-25

452 Transitions in filament geometry drive ESCRT-III-mediated membrane remodelling and fission

Harker-Kirschneck, L.; Baum, B.; Saric, A.

10.1101/559898 — biophysics — Posted on 2019-02-25

453 Super-resolution displacement mapping of unbound single molecules reveals nanoscale heterogeneities in intracellular diffusivity

Xiang, L.; Chen, K.; Yan, R.; Li, W.; Xu, K.

10.1101/559484 — biophysics — Posted on 2019-02-25

454 Peptide Secondary Structure Prediction using Evolutionary Information

Singh, H.; Singh, S.; Raghava, G. P. S.

10.1101/558791 — bioinformatics — Posted on 2019-02-25

455 BIQ: A method for searching circular RNAs in transcriptome databases by indexing backsplice junctions

Menzel, P.; Meyer, I. M.

10.1101/556993 — bioinformatics — Posted on 2019-02-25

456 Consistent and correctable bias in metagenomic sequencing measurements

McLaren, M. R.; Willis, A. D.; Callahan, B. J.

10.1101/559831 — bioinformatics — Posted on 2019-02-25

457 HH-suite3 for fast remote homology detection and deep protein annotation

Steinegger, M.; Meier, M.; Mirdita, M.; Voehringer, H.; Haunsberger, S. J.; Soeding, J.

10.1101/560029 — bioinformatics — Posted on 2019-02-25

458 LRRC33 is a novel binding and regulating protein of TGF-β1 function in human acute myeloid leukemia cells

Ma, W.; Qin, Y.; Chapuy, B.; Lu, C.

10.1101/560763 — biochemistry — Posted on 2019-02-25

459 The genome and mRNA transcriptome of the cosmopolitan calanoid copepod Acartia tonsa Dana improve the understanding of copepod genome size evolution

Jorgensen, T. S.; Petersen, B.; Jepsen, P. M.; van Someren Greve, H.; Hestbjerg Hansen, L.; Hansen, B. W.

10.1101/560102 — genomics — Posted on 2019-02-25

460 DrugComb - an integrative cancer drug combination data portal

Zagidullin, B.; Aldahdooh, J.; Zheng, S.; Wang, W.; Wang, Y.; Saad, J.; Malyutina, A.; Pessia, A.; Tang, J.

10.1101/560227 — pharmacology and toxicology — Posted on 2019-02-25

461 Anosognosia for Hemiplegia as a tripartite disconnection syndrome

Thiebaut de Schotten, M.; Pacella, V.; Foulon, C.; Scandola, M.; Bertagnoli, S.; Avesani, R.; Fotopoulou, K.; Moro, V.; Jenkinson, P.

10.1101/560326 — neuroscience — Posted on 2019-02-25

462 Estimation of Brain Age Delta from Brain Imaging

Smith, S. M.; Vidaurre, D.; Alfaro-Almagro, F.; Nichols, T. E.; Miller, K. L.

10.1101/560151 — neuroscience — Posted on 2019-02-25

463 Emergence of β and γ networks following multisensory training

La Rocca, D.; Ciuciu, P.; Engemann, D.-A.; van Wassenhove, V.

10.1101/560235 — neuroscience — Posted on 2019-02-25

464 Positive feedback loop of regulating ERK phosphorylation in mESCs mediated by Etv5-Tet2-Fgfr2 axis

Fan, C.; Zhu, K.; Liu, Y.; Zhang, M.; Cao, H.; Li, N.; Wang, Y.; Hua, J.; Wang, H.; Zhang, S.

10.1101/560334 — developmental biology — Posted on 2019-02-25

465 Basal protrusions mediate spatiotemporal patterns of spinal neuron differentiation

Hadjivasiliou, Z.; Moore, R.; McIntosh, R.; Galea, G.; Clarke, J.; Alexandre, P.

10.1101/559195 — developmental biology — Posted on 2019-02-25

466 Uniaxial loading induces a scalable switch in cortical actomyosin flow polarization and reveals mechanosensitive regulation of cytokinesis

Singh, D.; Odedra, D.; Pohl, C.

10.1101/560433 — cell biology — Posted on 2019-02-25

467 Serial horizontal transfer of vitamin-biosynthetic genes enables the establishment of new nutritional symbionts in aphids' di-symbiotic systems

Manzano-Marin, A.; Coeur d'acier, A.; Clamens, A.-L.; Orvain, C.; Cruaud, C.; Barbe, V.; Jousselin, E.

10.1101/556274 — genomics — Posted on 2019-02-25

468 Dynamic variability in apoptotic threshold as a strategy for combating fractional killing

Qiu, B.; Zhang, J.; Zhou, T.

10.1101/375915 — systems biology — Posted on 2019-02-24

469 Physiological Synchrony Predicts Observational Threat Learning in Humans

Pärnamets, P.; Espinosa, L.; Olsson, A.

10.1101/454819 — neuroscience — Posted on 2019-02-24

470 Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing

Senabouth, A.; Anderson, S.; Shi, Q.; Shi, L.; Jiang, F.; Zhang, W.; Wing, K.; Daniszewski, M.; Lukowski, S.; Hung, S.; Nguyen, Q.; Fink, L.; Beckhouse, A.; Pebay, A.; Hewitt, A.; Powell, J.

10.1101/552588 — genomics — Posted on 2019-02-24

471 Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis

Ferguson, S. M.; Roczniak-Ferguson, A.

10.1101/560144 — cell biology — Posted on 2019-02-25

472 The geography of the Anthropocene differs between the land and the sea

Bowler, D.; Bjorkmann, A.; Dornelas, M.; Myers-Smith, I.; Navarro, L.; Niamir, A.; Supp, S.; Waldock, C.; Vellend, M.; Blowes, S.; Boehning-Gaese, K.; Bruelheide, H.; Elahi, R.; Antao, L.; Hines, J.; Isbell, F.; Jones, H.; Magurran, A.; Cabral, J.; Winter, M.; Bates, A.

10.1101/432880 — ecology — Posted on 2019-02-24

473 Drivers of individual oak tree selection by acorn dispersing animals inferred from a genotyped seedling cohort

Gerzabek, G.; Klein, E. K.; Hampe, A.

10.1101/559179 — ecology — Posted on 2019-02-24

474 Parasite intensity is driven by temperature in a wild bird

Mennerat, A.; Charmantier, A.; Hurtrez-Bousses, S.; Perret, P.; Lambrechts, M. M.

10.1101/323311 — ecology — Posted on 2019-02-24

475 Massive computational acceleration by using neural networks to emulate mechanism-based biological models

Wang, S.; Kai, F.; Luo, N.; Cao, Y.; Wu, F.; Zhang, C.; Heller, K. A.; You, L.

10.1101/559559 — systems biology — Posted on 2019-02-24

476 Holding the arm still through subcortical mathematical integration of cortical commands

Albert, S. T.; Hadjiosif, A.; Jang, J.; Krakauer, J. W.; Shadmehr, R.

10.1101/556282 — neuroscience — Posted on 2019-02-24

477 Tractography in the presence of white matter lesions in multiple sclerosis

Lipp, I.; Parker, G. D.; Tallantyre, E.; Goodall, A.; Grama, S.; Patitucci, E.; Heveron, P.; Tomassini, V.; Jones, D.

10.1101/559708 — neuroscience — Posted on 2019-02-24

478 The Role of Proactive and Reactive Cognitive Control for Target Selection in Multiple-Target Search

Ort, E.; Fahrenfort, J. J.; Reeder, R. R.; Pollmann, S.; Olivers, C. N. L.

10.1101/559500 — neuroscience — Posted on 2019-02-24

479 Bacterial transformation buffers environmental fluctuations through the reversible integration of mobile genetic elements

Carvalho, G.; Fouchet, D.; Danesh, G.; Godeux, A.-S.; Laaberki, M.-H.; Pontier, D.; Charpentier, X.; Venner, S.

10.1101/557462 — microbiology — Posted on 2019-02-24

480 Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination

Hoehn, K. B.; Vander Heiden, J. A.; Zhou, J. Q.; Lunter, G.; Pybus, O. G.; Kleinstein, S.

10.1101/558825 — immunology — Posted on 2019-02-24

481 Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the associated provirus in thousands of cells with long reads

Artesi, M.; Hahaut, V.; Ashrafi, F.; Marcais, A.; Hermine, O.; Griebel, P.; Arsic, N.; van der Meer, F.; Burny, A.; Bron, D.; Charlier, C.; Georges, M.; Van den Broeke, A.; Durkin, K.

10.1101/558130 — genomics — Posted on 2019-02-24

482 Early life DNA methylation profiles are indicative of age-related transcriptome changes

Hadad, N.; Masser, D. R.; Blanco Berdugo, L. A.; Stanford, D. R.; Freeman, W. M.

10.1101/557892 — genomics — Posted on 2019-02-24

483 Modified Potential Functions Result in Enhanced Predictions of a Protein Complex by All-Atom MD Simulations, Confirming a Step-wise Association Process for Native PPIs

Li, Z.-l.; Buck, M.

10.1101/241810 — biophysics — Posted on 2019-02-24

484 Interaction of NPC2 protein with Lysobisphosphatidic Acid is required for normal endolysosomal cholesterol trafficking

McCauliff, L. A.; Langan, A.; Li, R.; Ilnytska, O.; Bose, D.; Kahn, P. C.; Storch, J.

10.1101/559849 — biochemistry — Posted on 2019-02-24

485 Personalized Therapy Design for Systemic Lupus Erythematosus Based on the Analysis of Protein-Protein Interaction Networks

Brant, E. J.; Rietman, E. A.; Lakka-Klement, G.; Cavaglia, M.; Tusznski, J. A.

10.1101/559740 — systems biology — Posted on 2019-02-24

486 Nanoparticle-mediated transformation expands horizon of organism engineering

French, K. E.

10.1101/559252 — synthetic biology — Posted on 2019-02-24

487 Computational redesign of the Escherichia coli ribose-binding protein ligand binding pocket for 1,3-cyclohexanediol and cyclohexanol

Tavares, D.; Reimer, A.; Roy, S.; Joublin, A.; Sentchilo, V.; van der Meer, J. R.

10.1101/559328 — synthetic biology — Posted on 2019-02-24

488 Big root approximation of site-scale vegetation water uptake

Bouda, M.

10.1101/559237 — plant biology — Posted on 2019-02-24

489 EXOCYST70A3 controls root system depth in Arabidopsis via the dynamic modulation of auxin transport

Ogura, T.; Goeschl, C.; Filiault, D.; Mirea, M.; Slovak, R.; Wolhrab, B.; Satbhai, S. B.; Busch, W.

10.1101/559187 — plant biology — Posted on 2019-02-24

490 Orthogonal Drug Pooling Enhances Phenotype-based Discovery of Ocular Anti-angiogenic Drugs in Zebrafish Larvae

Ohnesorge, N.; Sasore, T.; Hillary, D.; Alvarez, Y.; Carey, M.; Kennedy, B. N.

10.1101/559781 — pharmacology and toxicology — Posted on 2019-02-24

491 A deep learning approach for Pan-Renal Cell Carcinoma classification and survival prediction from histopathology images

Tabibu, S.; Vinod, P. K.; Jawahar, C. V.

10.1101/559401 — pathology — Posted on 2019-02-24

492 Experience-dependent tuning of early olfactory processing in the adult brain

Jernigan, C. M.; Halby, R.; Gerkin, R. C.; Sinakevitch, I.; Locatelli, F.; Smith, B. H.

10.1101/558734 — neuroscience — Posted on 2019-02-24

493 Post-decision processing in primate prefrontal cortex influences subsequent choices on an auditory decision-making task

Cohen, Y.; Gold, J.; tsunada, j.

10.1101/558759 — neuroscience — Posted on 2019-02-24

494 Generalizing to generalize: when (and when not) to be compositional in task structure learning

Franklin, N. T.; Frank, M. J.

10.1101/547406 — neuroscience — Posted on 2019-02-24

495 Tuned normalization in perceptual decision-making circuits can explain seemingly suboptimal confidence behavior

Maniscalco, B.; Odegaard, B.; Grimaldi, P.; Cho, S. H.; Basso, M. A.; Lau, H.; Peters, M. A. K.

10.1101/558858 — neuroscience — Posted on 2019-02-24

496 Genotype and dose-frequency determine acute and chronic effects of oxytocin on amygdala fear responses in humans: therapeutic implications

Kou, J.; Zhang, Y.; Zhou, F.; Sindermann, C.; Montag, C.; Becker, B.; Kendrick, K.

10.1101/493387 — neuroscience — Posted on 2019-02-24

497 A Bayesian framework for unifying data cleaning, source separation and imaging of electroencephalographic signals

Ojeda, A.; Klug, M.; Kreutz-Delgado, K.; Gramann, K.; Mishra, J.

10.1101/559450 — neuroscience — Posted on 2019-02-24

498 Sensorimotor system engagement during ASL sign perception: an EEG study in deaf signers and hearing non-signers

Kubicek, E.; Quandt, L.

10.1101/558833 — neuroscience — Posted on 2019-02-24

499 Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair

Srivastava, A.; Mishra, R.

10.1101/559641 — molecular biology — Posted on 2019-02-24

500 Allele-specific silencing ameliorates restrictive cardiomyopathy due to a human myosin regulatory light chain mutation

Zaleta, K.; Dainis, A.; Ribeiro, A. J. S.; Sanchez-Cordero, P.; Rubio, G.; Shang, C.; Liu, J.; Finsterbach, T.; Sinha, N.; Jain, N.; Hajjar, R.; Kay, M. A.; Szczesna-Corday, D.; Pruitt, B. L.; Wheeler, M. T.; Ashley, E. A.

10.1101/559468 — molecular biology — Posted on 2019-02-24

501 Tsr4 is a cytoplasmic chaperone for the ribosomal protein Rps2 in Saccharomyces cerevisiae

Black, J. J.; Musalgaonkar, S.; Johnson, A. W.

10.1101/559146 — molecular biology — Posted on 2019-02-24

502 ANP32A and ANP32B are key factors in the Rev dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA

Wang, Y.; Zhang, H.; Na, L.; Du, C.; Zhang, Z.; Zheng, Y.; Wang, X.

10.1101/559096 — microbiology — Posted on 2019-02-24

503 Extreme niche partitioning promotes a remarkably high diversity of soil microbiomes across eastern Antarctica.

Zhang, E.; Thibaut, L. M.; Terauds, A.; Wong, S.; van Dorst, J.; Tanaka, M. M.; Ferrari, B. C.

10.1101/559666 — microbiology — Posted on 2019-02-24

504 Growth Phase Dependent Chromosome Condensation and H-NS Protein Redistribution in E. coli Under Osmotic Stress

Rafiei, N.; Cordova, M.; Navarre, W. W.; Milstein, J.

10.1101/559138 — microbiology — Posted on 2019-02-24

505 Discordant gene responses to radiation in humans and mice: hematopoietically humanized mice may save the day for radiation biomarker identification.

Ghandhi, S.; Smilenov, L.; Pujol-Canadell, M.; Amundson, S. A.

10.1101/558882 — genomics — Posted on 2019-02-24

506 RPW8/HR Repeats Predict NLR-dependent Hybrid Performance

Barragan, C.; Wu, R.; Kim, S.-T.; Xi, W.; Habring, A.; Hagmann, J.; Van de Weyer, A.-L.; Zaidem, M.; Ho, W. W. H.; Wang, G.; Bezrukov, I.; Weigel, D.; Chae, E.

10.1101/559864 — genetics — Posted on 2019-02-24

507 Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA.

Guacci, V. A.; Chatterjee, F.; Robison, B.; Koshland, D.

10.1101/559492 — genetics — Posted on 2019-02-24

508 Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leukocyte antigen locus

Parks, T.; Elliott, K.; Lamagni, T.; Auckland, K.; Mentzer, A. J.; Guy, R.; Cartledge, D.; Strakova, L.; O'Connor, D.; Pollard, A. J.; Neville, M. J.; Mahajan, A.; Ashrafian, H.; Chapman, S. J.; Hill, A. V.; Sriskandan, S.; Knight, J.

10.1101/559161 — genetics — Posted on 2019-02-24

509 Accurate inference of tree topologies from multiple sequence alignments using deep learning

Suvorov, A.; Hochuli, J.; Schrider, D.

10.1101/559054 — evolutionary biology — Posted on 2019-02-24

510 The Linked Selection Signature of Rapid Adaptation in Temporal Genomic Data

Buffalo, V.; Coop, G.

10.1101/559419 — evolutionary biology — Posted on 2019-02-24

511 Demographic histories and genome-wide patterns of divergence in incipient species of shorebirds

Wang, X.; Maher, K. H.; Zhang, N.; Que, P.; Zheng, C.; Liu, S.; Wang, B.; Huang, Q.; Chen, D.; Yang, X.; Zhang, Z.; Szekely, T.; Urrutia, A.; Liu, Y.

10.1101/559633 — evolutionary biology — Posted on 2019-02-24

512 Human pathogen co-occurrence in Ixodes ricinus ticks: effects of landscape topography, climatic factors and microbiota interactions

Aivelo, T.; Norberg, A.; Tschirren, B.

10.1101/559245 — ecology — Posted on 2019-02-24

513 Temperature drives the evolution and global distribution of avian eggshell colour

Wisocki, P. A.; Kennelly, P.; Rojas Rivera, I.; Cassey, P.; Hanley, D.

10.1101/559435 — ecology — Posted on 2019-02-24

514 Loss of function mutation of mouse Snap29 on a mixed genetic background phenocopy abnormalities found in CEDNIK and 22q11.2 Deletion Syndrome patients

Keser, V.; Boisclair Lachance, J.-F.; Alam, S. S.; Lim, Y.; Scarlata, E.; Kaur, A.; Fang, Z. T.; Lv, S.; Lachapelle, P.; O'Flaherty, C.; Golden, J. A.; Jerome-Majewska, L. A.

10.1101/559088 — developmental biology — Posted on 2019-02-24

515 Clinical, imaging genetics and deformation based morphometry study of longitudinal changes after surgery for intractable aggressive behaviour

Venetucci Gouveia, F.; Germann, J.; Campelo Borba de Morais, R. M.; Talamoni Fonoff, E.; Hamani, C.; Alho, E. J.; Brentani, H.; Martins, A. P.; Devenyi, G. A.; Patel, R.; Steele, C. J.; Gramer, R.; Chakravarty, M. M.; Chacon Ruiz Martinez, R.

10.1101/548826 — clinical trials — Posted on 2019-02-24

516 Clueless forms dynamic, insulin-responsive bliss particles sensitive to stress

Sheard, K. M.; Thibault-Sennett, S. A.; Sen, A.; Shewmaker, F.; Cox, R. T.

10.1101/552455 — cell biology — Posted on 2019-02-24

517 Generation of dual specific bivalent BiTEs (dbBIspecific T-cell Engaging antibodies) for cellular immunotherapy

Kujawski, M.; Li, L.; Bhatacharya, S.; Wong, P.; Lee, W.-H.; (Obrien) Williams, L.; Li, H.; Cheah, J.; Poku, K.; Bowles, N.; Vaidehi, N.; Yazaki, P.; Shively, J. E.

10.1101/559427 — cancer biology — Posted on 2019-02-24

518 Pancreatic Stellate Cells Secrete Deoxycytidine Conferring Resistance to Gemcitabine in PDAC

Dalin, S.; Sullivan, M. R.; Kreidl, E.; Lau, A. N.; Grauman-Boss, B.; Fenoglio, S.; Luengo, A.; Vander Heiden, M. G.; Lauffenburger, D. A.; Hemann, M. T.

10.1101/558627 — cancer biology — Posted on 2019-02-24

519 Haplotype-aware graph indexes

Siren, J.; Garrison, E.; Novak, A. M.; Paten, B.; Durbin, R.

10.1101/559583 — bioinformatics — Posted on 2019-02-24

520 SAXSDom: Modeling multi-domain protein structures using small-angle X-ray scattering data

Hou, J.; Adhikari, B.; Tanner, J. J.; Cheng, J.

10.1101/559617 — bioinformatics — Posted on 2019-02-24

521 Discovery of biased orientation of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2019-02-24

522 Evaluation of computational genotyping of Structural Variations for clinical diagnoses.

Chander, V.; Gibbs, R. A.; Sedlazeck, F. J.

10.1101/558247 — bioinformatics — Posted on 2019-02-24

523 Allometric Scaling of physiologically-relevant organoids

Magliaro, C.; Rinaldo, A.; Ahluwalia, A.

10.1101/559682 — bioengineering — Posted on 2019-02-24

524 CHOLESTEROL MYTH AND THE IMPERATIVE ROLE OF FUNCTIONAL EVALUATION OF LIPOPROTEINS IN ATHEROSCLEROTIC RISK PREDICTION STRATEGIES

Ravi, D. B.; Srinivasan, A.; Velusamy, P.; S Narasimhan, K. K.; Chakrapani, L. N.; Singh, A.; Mohan, T.; Thiruvengadam, K.; Moongilpatti Angappa, A.; Periandavan, K.

10.1101/559625 — biochemistry — Posted on 2019-02-24

525 Assessing a commercial capillary electrophoresis interface (ZipChip) for shotgun proteomic applications

Rinas, A.; Jenkins, C.; Orsburn, B.

10.1101/559591 — biochemistry — Posted on 2019-02-24

526 Does insulin signalling decide glucose levels in the fasting steady state?

Watve, M.; Diwekar-Joshi, M.

10.1101/553016 — physiology — Posted on 2019-02-24

527 Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR/Cas9 screening

Garnett, M.; Picco, G.; Chen, E.; Garcia Alonso, L.; Behan, F.; Goncalves, E.; Bignell, G.; Matchan, A.; Fu, B.; Banerjee, R.; Anderson, E.; Butler, A.; Benes, C.; McDermott, U.; Dow, D.; Iorio, F.; Stronach, E.; Yang, F.; Yusa, K.; Saez-Rodriguez, J.

10.1101/559690 — cancer biology — Posted on 2019-02-24

528 Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM

Righetto, R.; Biyani, N.; Kowal, J.; Chami, M.; Stahlberg, H.

10.1101/488403 — biophysics — Posted on 2019-02-24

529 Cytoskeleton dynamics control early events of lateral root initiation in Arabidopsis

Vilches Barro, A.; Stoeckle, D.; Thellmann, M.; Ruiz Duarte, P.; Bald, L.; Louveaux, M.; von Born, P.; Denninger, P.; Goh, T.; Fukaki, H.; Vermeer, J.; Maizel, A.

10.1101/559443 — plant biology — Posted on 2019-02-24

530 Distinct Spinal V2a and V0d Microcircuits Distribute Locomotor Control in Larval Zebrafish

Menelaou, E.; Kishore, S.; McLean, D. L.

10.1101/559799 — neuroscience — Posted on 2019-02-24

531 Discovery of conformation-sensitive anti-amyloid protofibril monoclonal antibodies using an engineered chaperone-like amyloid-binding protein

Graham, W. V.; Bonito-Oliva, A.; Agostinelli, R.; Karim, R.; Deguzman, J.; Kelleher, K.; Petro, M.; Lindstrom, A.-K.; Graff, C.; Wood, K. M.; Tchistiakova, L.; Marquette, K.; Wes, P. D.; Sakmar, T. P.

10.1101/558809 — molecular biology — Posted on 2019-02-24

532 Mycobacterium tuberculosis detection from oral swabs with Xpert MTB/RIF ULTRA: A pilot study

Mesman, A.; Calderon, R.; Soto, M.; Coit, J.; Aliaga, J.; Mendoza, M.; Franke, M.

10.1101/559815 — microbiology — Posted on 2019-02-24

533 Ammonia-oxidizing archaea release a suite of organic compounds potentially fueling prokaryotic heterotrophy in the ocean

Bayer, B.; Hansman, R. L.; Bittner, M. J.; Noriega-Ortega, B. E.; Niggemann, J.; Dittmar, T.; Herndl, G. J.

10.1101/558726 — ecology — Posted on 2019-02-24

534 Insect herbivory and avian insectivory in novel native oak forests: divergent effects of stand size and connectivity

Valdes Correcher, E.; van Halder, I.; Barbaro, L.; Castagneyrol, B.; Hampe, A.

10.1101/558114 — ecology — Posted on 2019-02-24

535 RASSF1A Is Required For The Maintenance Of Nuclear Actin Levels

Chatzifrangkeskou, M.; Pefani, D.-E.; Eyres, M.; Vendrell, I.; Fischer, R.; Pankova, D.; O'Neill, E.

10.1101/559310 — cell biology — Posted on 2019-02-24

536 A small viral potassium ion channel with an inherent inward rectification

Eckert, D.; Schulze, T.; Stahl, J.; Rauh, O.; Van Etten, J. L.; Hertel, B.; Schroeder, I.; Moroni, A.; Thiel, G.

10.1101/559716 — biophysics — Posted on 2019-02-24

537 FQSqueezer: k-mer-based compression of sequencing data

Deorowicz, S.

10.1101/559807 — bioinformatics — Posted on 2019-02-24

538 Large-Scale Comparative Analysis of Codon Models Accounting for Protein and Nucleotide Selection

Davydov, I. I.; Salamin, N.; Robinson-Rechavi, M.

10.1101/174839 — bioinformatics — Posted on 2019-02-24

539 In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe

Volpe, M. R.; Wilson, M. R.; Brotherton, C. A.; Winter, E. S.; Johnson, S. E.; Balskus, E. P.

10.1101/559385 — biochemistry — Posted on 2019-02-24

540 Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi

Hai, Y.; Huang, A.; Tang, Y.

10.1101/559534 — biochemistry — Posted on 2019-02-24

541 Biochemical and structural characterization of a highly active branched-chain amino acid aminotransferase from Pseudomonas sp. for efficient biosynthesis of chiral amino acids

Zheng, X.; Cui, Y.; Li, T.; Li, R.; Guo, L.; Li, D.-F.; Wu, B.

10.1101/559120 — biochemistry — Posted on 2019-02-24

542 Gtf2i and Gtf2ird1 mutation are not sufficient to reproduce mouse phenotypes caused by the Williams Syndrome critical region

Kopp, N. D.; McCullough, K.; Maloney, S. E.; Dougherty, J. D.

10.1101/558544 — animal behavior and cognition — Posted on 2019-02-24

543 Persistence of neuronal representations through time and damage in the hippocampus.

Gonzalez, W. G.; Zhang, H.; Harutyunyan, A.; Lois, C.

10.1101/559104 — neuroscience — Posted on 2019-02-24

544 Central and peripheral innervation patterns of defined axial motor units in larval zebrafish

Bello-Rojas, S.; Istrate, A. E.; Kishore, S.; McLean, D. L.

10.1101/559062 — neuroscience — Posted on 2019-02-24

545 Optogenetic olfactory behavior depends on illumination characteristics

Tumkaya, T.; Stewart, J.; Burhanudin, S.; Claridge-Chang, A.

10.1101/559674 — neuroscience — Posted on 2019-02-24

546 Multiscale Adaptive Gabor Expansion (MAGE): Improved Detection of Transient Oscillatory Burst Amplitude and Phase

Canolty, R. T.; Womelsdorf, T.

10.1101/369116 — neuroscience — Posted on 2019-02-24

547 Comparing Task-Relevant Information Across Different Methods of Extracting Functional Connectivity

Benitez Stulz, S.; Insabato, A.; Deco, G.; Gilson, M.; Senden, M.

10.1101/509059 — neuroscience — Posted on 2019-02-24

548 Partitioning the genetic architecture of amyotrophic lateral sclerosis

Broce, I. J.; Fan, C. C.; Olney, N. T.; Lomen-Hoerth, C.; Finkbeiner, S.; Atassi, N.; Cudkowicz, M. E.; Paganoni, S.; Yokoyama, J. S.; Kao, A.; Dillon, W. P.; Glastonbury, C. M.; Hess, C. P.; van Rheenen, W.; Veldink, J. H.; Al-Chalabi, A.; Andreassen, O. A.; Dale, A. M.; Seeley, W. W.; Sugrue, L. P.; Ofori-Kuragu, A.; Karch, C. M.; Miller, B. L.; Desikan, R. S.

10.1101/505693 — genetics — Posted on 2019-02-24

549 Depletion of limiting rDNA structural complexes triggers chromosomal instability and replicative aging of Saccharomyces cerevisiae

Fine, R.; Maqani, N.; Li, M.; Franck, E.; Smith, J. S.

10.1101/380675 — genetics — Posted on 2019-02-24

550 Rabies-induced behavioural changes are key to rabies persistence in dog populations: investigation using a network-based model

Brookes, V. J.; Duerr, S.; Ward, M. P.

10.1101/554451 — epidemiology — Posted on 2019-02-24

551 Trends of Hospitalization in Acute Pancreatitis in Patients in the United States from 2001-2014

Argo, R.; Bianco, A.; Ricci, F.; Costa, D.; Casey, K.

10.1101/547273 — epidemiology — Posted on 2019-02-24

552 Plant-soil feedbacks trigger tannin evolution by niche construction: a spatial stoichiometric model

Arnoldi, J.-F.; Coq, S.; Kefi, S.; Ibanez, S.

10.1101/320572 — ecology — Posted on 2019-02-24

553 The inherent multidimensionality of temporal variability: How common and rare species shape stability patterns

Arnoldi, J.-F.; Loreau, M.; Haegeman, B.

10.1101/431296 — ecology — Posted on 2019-02-24

554 Species dispersal mediates opposing influences of a branching network on genetic variation in a metapopulation

Chiu, M.-C.; Li, B.; Nukazawa, K.; Carvajal, T.; Watanabe, K.

10.1101/550194 — ecology — Posted on 2019-02-24

555 Determining cellular CTCF and cohesin abundances to constrain 3D genome models

Cattoglio, C.; Pustova, I.; Walther, N.; Ho, J. J.; Hantsche-Grininger, M.; Inouye, C. J.; Hossain, M. J.; Dailey, G. M.; Ellenberg, J.; Darzacq, X.; Tjian, R.; Hansen, A. S.

10.1101/370650 — biophysics — Posted on 2019-02-24

556 Oxidation state dependent conformational changes of HMGB1 regulates the formation of the CXCL12/HMGB1 heterocomplex

Fassi, E. M. A.; Sgrignani, J.; D'Agostino, G.; Cecchinato, V.; Garofalo, M.; Grazioso, G.; Uguccioni, M.; Cavalli, A.

10.1101/555946 — biochemistry — Posted on 2019-02-24

557 High extracellular lactate increases reductive carboxylation in breast tissue cell lines grown under normoxic conditions

Brodsky, A. N.; Odenwelder, D. C.; Harcum, S. W.

10.1101/558296 — cancer biology — Posted on 2019-02-23

558 Galectin-3 inhibits Paracoccidioides brasiliensis growth and impacts paracoccidioidomycosis through multiple mechanisms

Hatanaka, O.; Rezende, C. P.; Moreno, P.; Fernandes, F. F.; Oliveira-Brito, P. K. M.; Martinez, R.; Coelho, C.; Roque-Barreira, M. C.; Casadevall, A.; Almeida, F.

10.1101/557918 — microbiology — Posted on 2019-02-23

559 Therapeutic Challenges of Multidrug Resistant Acinetobacter baumannii in Eastern Africa

Geteneh, A.; Demissew, A.; Admas, A.; Alemu, D.; Girma, L.

10.1101/558312 — microbiology — Posted on 2019-02-23

560 Plasmid-based CRISPR-Cas9 gene editing in multiple Candida species

Lombardi, L.; Oliveira-Pacheco, J.; Butler, G.

10.1101/557926 — genetics — Posted on 2019-02-23

561 Tissue-specific mouse mRNA isoform networks

Kandoi, G.; Dickerson, J.

10.1101/558361 — bioinformatics — Posted on 2019-02-23

562 Cellular heterogeneity results from indirect effects under metabolic tradeoffs

Sole, R.; Olle, A.

10.1101/558619 — systems biology — Posted on 2019-02-23

563 Mechanics of membrane internalization against osmotic pressure: boundary conditions make a difference

MA, R.; Berro, J.

10.1101/558890 — biophysics — Posted on 2019-02-22

564 Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro

Kosyakova, N.; Kao, D. D.; Lopez-Giraldez, F.; Spindler, S.; Graham, M.; James, K. J.; Shin, J. W.; Liu, X.; Tietjen, G. T.; Pober, J. S.; Chang, W. G.

10.1101/558841 — cell biology — Posted on 2019-02-22

Tiek, D. M.; Khatib, S. A.; Trepicchio, C. J.; Heckler, M. M.; Divekar, S. D.; Sarkaria, J. N.; Glasgow, E.; Riggins, R. B.

10.1101/558775 — cancer biology — Posted on 2019-02-22

566 Phosphoinositides regulate the TRPV1 channel via two functionally distinct binding sites

Yazici, A. T.; Gianti, E.; Kasimova, M. A.; Carnevale, V.; Rohacs, T.

10.1101/558874 — biophysics — Posted on 2019-02-22

567 High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

10.1101/559021 — pathology — Posted on 2019-02-22

568 Temporal dynamics of inhalation-linked activity across defined subpopulations of mouse olfactory bulb neurons imaged in vivo.

Short, S. M.; Wachowiak, M.

10.1101/558999 — neuroscience — Posted on 2019-02-22

569 Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea

Kuzmenko, A.; Yudin, D.; Ryazansky, S.; Kulbachinskiy, A.; Aravin, A.

10.1101/558684 — molecular biology — Posted on 2019-02-22

570 Gene-drive-mediated extinction is thwarted by evolution of sib mating

Bull, J. J.; Remien, C. H.; Krone, S. M.

10.1101/558924 — evolutionary biology — Posted on 2019-02-22

571 CHETAH: a selective, hierarchical cell type identification method for single-cell RNA sequencing

de Kanter, J. K.; Lijnzaad, P.; Candelli, T.; Margaritis, T.; Holstege, F.

10.1101/558908 — bioinformatics — Posted on 2019-02-22

572 Individual alpha frequency increases during a task but is unchanged by alpha-band flicker

Gray, M. J.; Emmanouil, T. A.

10.1101/559047 — neuroscience — Posted on 2019-02-22

573 cis-Regulatory Chromatin Contacts in Neural Cells Reveal Contributions of Genetic Variants to Complex Neurological Disorders

Song, M.; Yang, X.; Ren, X.; Maliskova, L.; Li, B.; Jones, I.; Wang, C.; Jacob, F.; Wu, K.; Traglia, M.; Tam, T. W.; Jamieson, K.; Lu, S.-Y.; Ming, G.-L.; Yao, J.; Weiss, L. A.; Dixon, J.; Judge, L. M.; Conklin, B. R.; Song, H.; Gan, L.; Shen, Y.

10.1101/494450 — genomics — Posted on 2019-02-22

574 Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

Doyle, S. R.; Illingworth, C. J. R.; Laing, R.; Bartley, D. J.; Redman, E.; Martinelli, A.; Holroyd, N.; Morrison, A. A.; Rezansoff, A.; Tracey, A.; Devaney, E.; Berriman, M.; Sargison, N.; Cotton, J. A.; Gilleard, J. S.

10.1101/298901 — genomics — Posted on 2019-02-22

575 Activity-dependent maturation of prefrontal gamma oscillations sculpts cognitive performance

Bitzenhofer, S. H.; Poepplau, J. A.; Chini, M.; Marquardt, A.; Hanganu-Opatz, I.

10.1101/558957 — neuroscience — Posted on 2019-02-22

576 Functional Enrichment and Analysis of Antigen-Specific Memory B Cell Antibody Repertoires in PBMCs

Waltari, E.; McGeever, A.; Kim, P. S.; McCutcheon, K. M.

10.1101/557769 — immunology — Posted on 2019-02-22

577 Phosphorylation of Nephrin induces phase separated domains that move through actomyosin contraction

Kim, S.; Kalappurakkal, J. M.; Mayor, S.; Rosen, M. K.

10.1101/558965 — cell biology — Posted on 2019-02-22

578 Highly sensitive and multiplexed in situ protein profiling with cleavable fluorescent streptavidin

Liao, R.; Mastroeni, D.; Coleman, P. D.; Guo, J.

10.1101/555615 — systems biology — Posted on 2019-02-22

579 Analysis of synapse-level neuronal morphology in human post-mortem brain tissue

Das, S. C.; Chen, D.; Callor, W. B.; Christensen, E.; Coon, H.; williams, m. E.

10.1101/558817 — neuroscience — Posted on 2019-02-22

580 Age and sex-dependent patterns of gut microbial diversity in human adults

de la Cuesta-Zuluaga, J.; Kelley, S. T.; Chen, Y.; Escobar, J. S.; Mueller, N. T.; Ley, R. E.; McDonald, D.; Huang, S.; Swafford, A. D.; Knight, R.; Thackray, V.

10.1101/544270 — microbiology — Posted on 2019-02-22

581 Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion

Rutkowski, T. P.; Purcell, R. H.; Pollak, R. M.; Grewenow, S. M.; Gafford, G. M.; Malone, T.; Khan, U.; Schroeder, J. P.; Epstein, M. P.; Bassell, G. J.; Warren, S. T.; Weinshenker, D.; Caspary, T.; Mulle, J. G.

10.1101/479949 — genetics — Posted on 2019-02-22

582 Tobacco exposure associated with oral microbiota oxygen utilization in the New York City Health and Nutrition Examination Study

Beghini, F.; Renson, A.; Zolnik, C.; Geistlinger, L.; Usyk, M.; Moody, T. U.; Thorpe, L.; Dowd, J. B.; Burk, R.; Segata, N.; Jones, H. E.; Waldron, L. D.

10.1101/470286 — epidemiology — Posted on 2019-02-22

583 12h-clock control of central dogma information flow by XBP1s

Pan, Y.; Ballance, H.; Meng, H.; Gonzalez, N.; Dacso, C.; Chen, X.; Levy, O.; Coarfa, C.; O'Malley, B.; Zhu, B.

10.1101/559039 — systems biology — Posted on 2019-02-22

584 Unbiased estimation of linkage disequilibrium from unphased data

Ragsdale, A. P.; Gravel, S.

10.1101/557488 — genetics — Posted on 2019-02-22

585 FinDonor 10 000 study: A cohort to identify iron depletion and factors affecting it in Finnish blood donors

Partanen, J.; Niittymaki, P.; Nikiforow, N.; Palokangas, E.; Lobier, M.; Larjo, A.; Mattila, P.; Castren, J.; Arvas, M.

10.1101/507665 — epidemiology — Posted on 2019-02-22

586 YAP is involved in replenishment of granule cell progenitors following injury to the neonatal cerebellum

Yang, Z.; Joyner, A. L.

10.1101/558742 — developmental biology — Posted on 2019-02-22

587 Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 CNV Mediated Risk for Neuropsychiatric Disorders

Forsyth, J. K.; Nachun, D.; Gandal, M. J.; Geschwind, D. H.; Anderson, A. E.; Coppola, G.; Bearden, C. E.

10.1101/555490 — systems biology — Posted on 2019-02-22

588 Neural Circuit Mechanism of Decision Uncertainty and Change-of-Mind

Atiya, N. A. A.; Rano, I.; Prasad, G.; Wong-Lin, K.

10.1101/377432 — neuroscience — Posted on 2019-02-22

589 A bacterial size law revealed by a coarse-grained model of cell physiology

Bertaux, F.; Von Kügelgen, J.; Marguerat, S.; Shahrezaei, V.

10.1101/078998 — biophysics — Posted on 2019-02-22

590 Subcellular localization of drug distribution by super-resolution ion beam imaging

Rovira-Clave, X.; Jiang, S.; Bai, Y.; Barlow, G. L.; Bhate, S.; Coskun, A.; Han, G.; Zhu, B.; Ho, C.-M.; Hitzman, C.; Chen, S.-Y.; Bava, F.-A.; Nolan, G.

10.1101/557603 — systems biology — Posted on 2019-02-22

591 Rapid, multiplexed, whole genome and plasmid sequencing of foodborne pathogens using long-read nanopore technology

Taylor, T. L.; Volkening, J. D.; DeJesus, E.; Simmons, M.; Dimitrov, K. M.; Tillman, G. E.; Suarez, D. L.; Afonso, C. L.

10.1101/558718 — microbiology — Posted on 2019-02-22

592 Transcript fusion between CDKN1A and RAB44 caused by exon skipping like mechanism due to disruption of a splice site

Sun, H.; Wei, W.; Steinmetz, L.

10.1101/111856 — genetics — Posted on 2019-02-22

593 Human genetic disease is greatly influenced by the underlying fragility of evolutionarily ancient genes

Martin-Geary, A.; Reardon, M.; Keith, B.; Tassabehji, M.; Robertson, D. L.

10.1101/558916 — genetics — Posted on 2019-02-22

594 Asymmetric post-translational modifications regulate the intracellular distribution of unstimulated STAT3 dimers

Cardoso, B.; Letra-Vilela, R.; Silva-Almeida, C.; Rocha, A. M.; Murtinheira, F.; Rodriguez, C.; Martin, V.; Herrera, F.

10.1101/546523 — cell biology — Posted on 2019-02-22

595 A multiscale analysis of DNA phase separation: From atomistic to mesoscale level

Sun, T.; Mirzoev, A.; Minhas, V.; Korolev, N.; Lyubartsev, A. P.; Nordenskioeld, L.

10.1101/375626 — biophysics — Posted on 2019-02-22

596 Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM

Righetto, R.; Biyani, N.; Kowal, J.; Chami, M.; Stahlberg, H.

10.1101/488403 — biophysics — Posted on 2019-02-22

597 Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming

Ahmed, N.; Sormanni, P.; Ciryam, P.; Vendruscolo, M.; Dobson, C. M.; O'Brien, E. P.

10.1101/490755 — bioinformatics — Posted on 2019-02-22

598 Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal homeostasis and survival in Drosophila

Sharma, A.; Akagi, K.; Pattavina, B.; Wilson, K. A.; Nelson, C.; Watson, M.; Maksoud, E.; Ortega, M.; Brem, R.; Kapahi, P.

10.1101/540377 — molecular biology — Posted on 2019-02-22

599 Variation in genome content and predatory phenotypes between Bdellovibrio sp. NC01 isolated from soil and B. bacteriovorus type strain HD100

Williams, L. E.; Cullen, N.; DeGiorgis, J. A.; Martinez, K. J.; Mellone, J.; Oser, M.

10.1101/551937 — microbiology — Posted on 2019-02-22

600 Emergence of stable coexistence in a complex microbial community through metabolic cooperation and spatio-temporal niche partitioning

Blasche, S.; Kim, Y.; Mars, R.; Kafkia, E.; Maansson, M.; Machado, D.; Teusink, B.; Nielsen, J.; Benes, V.; Neves, R.; Sauer, U.; Patil, K. R.

10.1101/541870 — microbiology — Posted on 2019-02-22

601 Combined linkage and association mapping of putative QTLs controlling black tea quality and drought tolerance traits

Koech, R.; Mose, R.; Kamunya, S.; Apostolides, Z.

10.1101/458596 — genomics — Posted on 2019-02-22

602 Information and genetic counselling for psychiatric risks in children with rare disorders

Cuthbert, A.; Challenger, A.; Hall, J.; van den Bree, M.

10.1101/542423 — genetics — Posted on 2019-02-22

603 Impact of mutation rate and selection at linked sites on fine-scale DNA variation across the homininae genome

Castellano, D.; Eyre-Walker, A.; Munch, K.

10.1101/452201 — evolutionary biology — Posted on 2019-02-22

604 The determinants of genetic diversity in butterflies - Lewontin's paradox revisited

Mackintosh, A. J.; Laetsch, D. R.; Hayward, A.; Charlesworth, B.; Waterfall, M.; Vila, R.; Lohse, K.

10.1101/534123 — evolutionary biology — Posted on 2019-02-22

605 Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

Matson, J. P.; House, A. M.; Grant, G. D.; Wu, H.; Perez, J.; Cook, J.

10.1101/558783 — cell biology — Posted on 2019-02-22

606 A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance

Boyer, N. P.; McCormick, L. E.; Urbina, F. L.; Gupton, S.

10.1101/529222 — cell biology — Posted on 2019-02-22

607 The promoter regions of intellectual disability-associated genes are uniquely enriched in LTR sequences of the MER41 primate-specific endogenous retrovirus: an evolutionary connection between immunity and cognition

Nataf, S.; Uriagereka, J.; Benitez-Burraco, A.

10.1101/434209 — neuroscience — Posted on 2019-02-22

608 Identification and functional characterization of two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome without electrolyte imbalance

Nadella, R. K.; Chellappa, A.; Subramaniam, A. G.; More, R. P.; Shetty, S.; Prakash, S.; Ratna, N.; VP, V.; Purushotham, M.; Saini, J.; Viswanath, B.; PS, B.; Nagappa, M.; Mehta, B.; Jain, S.; Kannan, R.

10.1101/506949 — neuroscience — Posted on 2019-02-22

609 Data-driven spatial filtering for improved measurement of cortical tracking of multiple representations of speech

Lesenfants, D.; Vanthornhout, J.; Verschueren, E.; Francart, T.

10.1101/551218 — neuroscience — Posted on 2019-02-22

610 SosA inhibits cell division in Staphylococcus aureus in response to DNA damage

Bojer, M. S.; Wacnik, K.; Kjelgaard, P.; Gallay, C.; Bottomley, A. L.; Cohn, M. T.; Lindahl, G.; Frees, D.; Veening, J.-W.; Foster, S. J.; Ingmer, H.

10.1101/364299 — microbiology — Posted on 2019-02-22

611 Ecological drivers of jellyfish blooms - the complex life history of a cosmopolitan medusa (Aurelia aurita)

Goldstein, J.; Steiner, U. K.

10.1101/102814 — ecology — Posted on 2019-02-22

612 Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm

Stevens, A.; Smith, H.; Garner, T.; Minogue, B.; Sneddon, S.; Shaw, L.; Keramari, M.; Oldershaw, R.; Bates, N.; Brison, D.; Kimber, S.

10.1101/411439 — developmental biology — Posted on 2019-02-22

613 Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types

Fujimoto, A.; Fujita, M.; Hasegawa, T.; Maejima, K.; Nakano, K.; Oku-Sasaki, A.; Wong, J. H.; Shiraishi, Y.; Miyano, S.; Imoto, S.; Stratton, M. R.; Rosen, S. G.; Nakagawa, H.

10.1101/406975 — cancer biology — Posted on 2019-02-22

614 Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes

Elias-Villalobos, A.; Toullec, D.; Faux, C.; Seveno, M.; Helmlinger, D.

10.1101/524959 — biochemistry — Posted on 2019-02-22

615 The structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin

Flydal, M. I.; Alcorlo-Pages, M.; Johannessen, F. G.; Martinez-Caballero, S.; Skaejrven, L.; Fernandez-Leiro, R.; Martinez, A.; Hermoso, J. A.

10.1101/552281 — biochemistry — Posted on 2019-02-22

616 The Fate of Glutamine in Human Metabolism. The interplay with glucose in proliferating cells.

MAZAT, J.-P.; RANSAC, S.

10.1101/477224 — systems biology — Posted on 2019-02-22

617 Idiosyncratic choice bias in decision tasks naturally emerges from intrinsic stochasticity in neuronal network dynamics

Lebovich, L.; Darshan, R.; Lavi, Y.; Hansel, D.; Loewenstein, Y.

10.1101/284877 — neuroscience — Posted on 2019-02-22

618 Necrotizing enterocolitis is preceded by increased gut bacterial replication, Klebsiella, and fimbriae-encoding bacteria that may stimulate TLR4 receptors

Olm, M. R.; Bhattacharya, N.; Crits-Christoph, A.; Firek, B. A.; Baker, R.; Song, Y. S.; Morowitz, M. J.; Banfield, J. F.

10.1101/558676 — microbiology — Posted on 2019-02-22

619 A post-translational modification of the sheath 1 modulates Francisella type VI secretion system assembly and function

ZIVERI, J.; CCHUON, C.; JAMET, A.; PRIGENT, G.; RYTTER, H.; TROS, F.; BAREL, M.; COUREUIL, m.; LAYS, C.; HENRY, t.; KEEP, N.; GUERRERA, C. I.; CHARBIT, A.

10.1101/370957 — microbiology — Posted on 2019-02-22

620 Convergence in form and function overcomes non-parallel evolutionary histories in a Holarctic fish

Jacobs, A.; Carruthers, M.; Yurchenko, A.; Gordeeva, N.; Alekseyev, S.; Hooker, O.; Leong, J.; Minckley, D. R.; Rondeau, E.; Koop, B.; Adams, C. E.; Elmer, K. R.

10.1101/265272 — evolutionary biology — Posted on 2019-02-22

621 Complete assembly of Escherichia coli ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts

Decano, A. G.; Ludden, C.; Feltwell, T.; Judge, K.; Parkhill, J.; Downing, T.

10.1101/558635 — genomics — Posted on 2019-02-22

622 Early sex-chromosome evolution in the diploid dioecious plant Mercurialis annua

Veltsos, P.; Ridout, K. E.; Toups, M. A.; Gonzalez-Martinez, S.; Muyle, A.; Emery, O.; Rastas, P.; Hudzieczek, V.; Hobza, R.; Vyskot, B.; Marais, G. A.; Filatov, D. A.; Pannell, J. R.

10.1101/106120 — genomics — Posted on 2019-02-22

623 Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the associated provirus in thousands of cells with long reads

Artesi, M.; Hahaut, V.; Ashrafi, F.; Marcais, A.; Hermine, O.; Griebel, P.; Arsic, N.; van der Meer, F.; Burny, A.; Bron, D.; Charlier, C.; Georges, M.; Van den Broeke, A.; Durkin, K.

10.1101/558130 — genomics — Posted on 2019-02-22

624 Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling

Liu, Y.; Li, Y.; Eyo, U. B.; Chen, T.; Umpierre, A.; Zhu, J.; Bosco, D. B.; Dong, H.; Wu, L.-J.

10.1101/557686 — neuroscience — Posted on 2019-02-22

625 Mouse navigation strategies for odor source localization

Liu, A.; Papale, A.; Hengenius, J.; Patel, K.; Ermentrout, B.; Urban, N.

10.1101/558643 — neuroscience — Posted on 2019-02-22

626 Glutarate metabolism in Pseudomonas putida is regulated by two distinct glutarate sensing transcription factors

Thompson, M. G.; Cruz-Morales, P.; Krishna, R. N.; Blake-Hedges, J. M.; Incha, M. R.; Keasling, J. D.

10.1101/557751 — microbiology — Posted on 2019-02-22

627 Cooler: scalable storage for Hi-C data andother genomically-labeled arrays

Abdennur, N.; Mirny, L.

10.1101/557660 — bioinformatics — Posted on 2019-02-22

628 ClassiPhages 2.0: Sequence-based classification of phages using Artificial Neural Networks

Chibani, C. M.; Meinecke, F.; Farr, A.; Dietrich, S.; Liesegang, H.

10.1101/558171 — bioinformatics — Posted on 2019-02-22

629 Systematic identification of circular RNAs and corresponding regulatory networks unveil their potential roles in the midgut of Apis cerana cerana workers

Chen, D.; Chen, H.; Du, Y.; Geng, S.; Xiong, C.; Zheng, Y.; Hou, C.; Diao, Q.; Guo, R.

10.1101/558049 — molecular biology — Posted on 2019-02-22

630 Gut Microbiome Analysis In Adult Tropical Gars (Atractosteus tropicus)

Mendez-Perez, R.; Garcia-Lopez, R.; Bautista-Lopez, J. S.; Vazquez-Castellanos, J. F.; Pena-Marin, E.; Martinez-Garcia, R.; Dominguez-Rodriguez, V. I.; Adams-Schroeder, R. H.; Baltierra-Trejo, E.; Melgar-Valdes, C.; Moya, A.; Alvarez-Gonzalez, C. A.; Gomez-Cruz, R.

10.1101/557629 — microbiology — Posted on 2019-02-22

631 Exploiting the 'survival of the likeliest' to enable evolution-guided drug design

Liu, C.; Leighow, S.; Inam, H.; Zhao, B.; Pritchard, J. R.

10.1101/557645 — evolutionary biology — Posted on 2019-02-22

632 Latent Space Phenotyping: Automatic Image-Based Phenotyping for Treatment Studies

Ubbens, J. R.; Cieslak, M.; Prusinkiewicz, P.; Stavness, I.

10.1101/557678 — plant biology — Posted on 2019-02-22

633 Chronic Ethanol Differentially Modulates Glutamate Release from Dorsal and Ventral Prefrontal Cortical Inputs onto Rat Basolateral Amygdala Principal Neurons

McGinnis, M. M.; Parrish, B. C.; Chappell, A. M.; McCool, B. A.

10.1101/558189 — neuroscience — Posted on 2019-02-22

634 Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication

Jerome, H.; Rudolf, M.; Lelke, M.; Pahlmann, M.; Busch, C.; Bockholt, S.; Wurr, S.; Gunther, S.; Rosenthal, M.; Kerber, R.

10.1101/556738 — molecular biology — Posted on 2019-02-22

635 Mechanochemical coupling and junctional forces during collective cell migration

Bui, J.; Conway, D. E.; Heise, R. L.; Weinberg, S. H.

10.1101/558452 — biophysics — Posted on 2019-02-22

636 A comparison of three programming languages for a full-fledged next-generation sequencing tool

Costanza, P.; Herzeel, C.; Verachtert, W.

10.1101/558056 — bioinformatics — Posted on 2019-02-22

637 Evaluation of computational genotyping of Structural Variations for clinical diagnoses.

Chander, V.; Gibbs, R. A.; Sedlazeck, F. J.

10.1101/558247 — bioinformatics — Posted on 2019-02-22

638 Rapid and scalable in vitro production of single-stranded DNA

Minev, D.; Guerra, R.; Kishi, J.; Smith, C.; Krieg, E.; Said, K.; Hornick, A.; Sasaki, H.; Filsinger, G.; Beliveau, B.; Yin, P.; Church, G.; Shih, W.

10.1101/558429 — molecular biology — Posted on 2019-02-22

639 Evolutionary conserved canonical BMP activity controls cortical neurogenesis

Najas, S.; Pijuan, I.; Esteve-Codina, A.; Usieto, S.; Martinez, J. D.; Zwijsen, A.; Arbones, M. L.; Marti, E.; Le Dreau, G.

10.1101/558486 — developmental biology — Posted on 2019-02-22

640 PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer

Santiago-Gomez, A.; Dragoni, I.; NicAmhlaoibh, R.; Trivier, E.; Sabin, V.; Simoes, B. M.; Gee, J. M.; Sims, A. H.; Howell, S. J.; Clarke, R.

10.1101/558528 — cancer biology — Posted on 2019-02-22

641 CANCER-ASSOCIATED FIBROBLASTS PROMOTE PROSTATE CANCER MALIGNANCY VIA METABOLIC REWIRING AND MITOCHONDRIAL TRANSFER

Ippolito, L.; Morandi, A.; Taddei, M. L.; Parri, M.; Comito, G.; Iscaro, A.; Raspollini, M. R.; Magherini, F.; Rapizzi, E.; Masquelier, J.; Muccioli, G. G.; Sonveaux, P.; Chiarugi, P.; Giannoni, E.

10.1101/558080 — cancer biology — Posted on 2019-02-22

642 Leveraging high-powered RNA-Seq datasets to improve inference of regulatory activity in single-cell RNA-Seq data

Wang, N.; Teschendorff, A. E.

10.1101/553040 — bioinformatics — Posted on 2019-02-22

643 Short-term consumption of sucralose with, but not without, carbohydrate impairs neural and metabolic sensitivity to sugar

Dalenberg, J. R.; Patel, B. P.; Denis, R.; Veldhuizen, M. G.; Nakamura, Y.; Vinke, P. C.; Luquet, S.; Small, D. M.

10.1101/557801 — physiology — Posted on 2019-02-22

644 A voltage-based metaplasticity rule applied to the model hippocampal granule cell accounts for homeostatic heterosynaptic plasticity

Shirrafiardekani, A.; Benuskova, L.; Frauendiener, J.

10.1101/557173 — neuroscience — Posted on 2019-02-22

645 Spatiotemporal functional organization of excitatory synaptic inputs onto macaque V1 neurons

Ju, N.; Li, Y.; Liu, F.; Jiang, H.; Macknik, S. L.; Martinez-Conde, S.; Tang, S.

10.1101/558163 — neuroscience — Posted on 2019-02-22

646 The Importance of Anti-Correlations in Graph Theory Based Classification of Autism Spectrum Disorder

Kazeminejad, A.; Sotero, R.

10.1101/557512 — neuroscience — Posted on 2019-02-22

647 A deconvolution algorithm for multiecho functional MRI: Multiecho Sparse Paradigm Free Mapping

Caballero Gaudes, C.; Moia, S.; Pawar, P.; Bandettini, P. A.; Gonzalez-Castillo, J.

10.1101/558288 — neuroscience — Posted on 2019-02-22

648 Invaders weather the weather: rapid adaptation to a novel environment occurs despite reduced genetic diversity

Selechnik, D.; Richardson, M. F.; Shine, R.; DeVore, J.; Ducatez, S.; Rollins, L. A.

10.1101/557868 — evolutionary biology — Posted on 2019-02-22

649 Facets of diazotrophy in the OMZ off Peru revisited: what we could not see from a single marker gene approach

Christiansen, C. F.; Loescher, C. R.

10.1101/558072 — ecology — Posted on 2019-02-22

650 Heart rate and its relationship with activity in free-ranging Cheloniidae sea turtles

Okuyama, J.; Shiozawa, M.; Shiode, D.

10.1101/557884 — animal behavior and cognition — Posted on 2019-02-22

651 A Systematic Assessment Of Current Genome-Scale Metabolic Reconstruction Tools

Mendoza, S. N.; Olivier, B. G.; Molenaar, D.; Teusink, B.

10.1101/558411 — systems biology — Posted on 2019-02-22

652 Arabidopsis mlo3 mutant plants exhibit spontaneous callose deposition and signs of early leaf senescence

Kusch, S.; Thiery, S.; Reinstädler, A.; Gruner, K.; Zienkiewicz, K.; Feussner, I.; Panstruga, R.

10.1101/558122 — plant biology — Posted on 2019-02-22

653 Brassinosteroids control gravitropism by changing cellulose orientation and mannan content in Arabidopsis hypocotyls

Somssich, M.; Vandenbussche, F.; Ivakov, A.; Funke, N.; Ruprecht, C.; Vissenberg, K.; Van Der Straeten, D.; Persson, S.; Suslov, D.

10.1101/557777 — plant biology — Posted on 2019-02-22

654 Characterizing grapevine (Vitis spp.) inflorescence architecture using X-ray imaging: implications for understanding cluster density

Li, M.; Klein, L. L.; Duncan, K. E.; Jiang, N.; Londo, J. P.; Miller, A.; Topp, C.

10.1101/557819 — plant biology — Posted on 2019-02-22

655 Mechanisms Underlying the Enhanced Biomass and Abiotic Stress Tolerance Phenotypes of an Arabidopsis MIOX Over expresser

Nepal, N.; Yactayo-Chang, J. P.; Medina-Jimenez, K.; Acosta-Gamboa, L. M.; Gonzalez-Romero, M. E.; Arteaga-Vazquez, M. A.; Lorence, A.

10.1101/558239 — plant biology — Posted on 2019-02-22

656 Precision-weighting of superior frontal cortex unsigned prediction error signals benefits learning, is mediated by dopamine, and is impaired in psychosis.

Haarsma, J.; Fletcher, P.; Griffin, J.; Taverne, H.; Ziauddeen, H.; Spencer, T.; Goodyer, I.; Diederen, K.; Murray, G.

10.1101/558478 — neuroscience — Posted on 2019-02-22

657 ANME-2d anaerobic methanotrophic archaea differ from other ANME archaea in lipid composition and carbon source

Kurth, J. M.; Smit, N. T.; Berger, S.; Schouten, S.; Jetten, M. M. S.; Welte, C. U.

10.1101/558007 — microbiology — Posted on 2019-02-22

658 Pathogen-encoded evasion of CXCL10 and T cell responses

Antonia, A. L.; Alvarez, M. I.; Trahair, E.; Gibbs, K. D.; Pittman, K. J.; Barnes, A. B.; Smith, J. S.; Rajagopal, S.; Thompson, J. W.; Reinhardt, R. L.; Ko, D. C.

10.1101/557876 — microbiology — Posted on 2019-02-22

659 The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter

Woldemeskel, S. A.; Alvarez, L.; Daitch, A. K.; Zeinert, R.; Bhargava, A.; Gonzalez, D.; Collier, J.; Chien, P.; Cava, F.; Goley, E.

10.1101/557637 — microbiology — Posted on 2019-02-22

660 Genomic analysis reveals a functional role for myocardial trabeculae in adults

Meyer, H. V.; Dawes, T. J.; Serrani, M.; Bai, W.; Tokarczuk, P.; Cai, J.; de Marvao, A.; Rueckert, D.; Matthews, P. M.; Costantino, M. L.; Birney, E.; Cook, S. A.; O'Regan, D. P.

10.1101/553651 — genomics — Posted on 2019-02-22

661 Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly

Bridavsky, M.; Kuhl, H.; Woodruf, A.; Kornak, U.; Timmermann, B.; Mages, N.; 99 Lives Consortium, ; Lupianez, D. G.; Symmons, O.; Ibrahim, D. M.

10.1101/556761 — genetics — Posted on 2019-02-22

662 Cell-type specific mechanical response and actomyosin dynamics in the developing Drosophila retina

Blackie, L.; Staddon, M. F.; Banerjee, S.; Pichaud, F.

10.1101/558593 — developmental biology — Posted on 2019-02-22

663 A machine learning tool for interpreting differences in cognition using brain features

Azevedo, T.; Passamonti, L.; Lio, P.; Toschi, N.

10.1101/558403 — neuroscience — Posted on 2019-02-22

664 Consciousness as a Concrete Physical Phenomenon

Jylkka, J.; Railo, H.

10.1101/557561 — neuroscience — Posted on 2019-02-22

665 Altered brain morphology in boys with attention-deficit/hyperactivity disorder with and without comorbid conduct disorder/oppositional defiant disorder

Vetter, N. C.; Backhausen, L. L.; Buse, J.; Roessner, V.; Smolka, M. N.

10.1101/553552 — neuroscience — Posted on 2019-02-22

666 A Sir2-regulated locus control region in the recombination enhancer of Saccharomyces cerevisiae specifies chromosome III structure

Li, M.; Fine, R.; Dinda, M.; Bekiranov, S.; Smith, J. S.

10.1101/558494 — molecular biology — Posted on 2019-02-22

667 Unbiased estimation of linkage disequilibrium from unphased data

Ragsdale, A. P.; Gravel, S.

10.1101/557488 — genetics — Posted on 2019-02-22

668 Genetic and genomic analyses reveal boundaries between species closely related to Cryptococcus pathogens

Passer, A. R.; Coelho, M. A.; Billmyre, R. B.; Nowrousian, M.; Mittelbach, M.; Yurkov, A. M.; Averette, A. F.; Cuomo, C. A.; Sun, S.; Heitman, J.

10.1101/557140 — evolutionary biology — Posted on 2019-02-22

669 Single mRNP analysis by super-resolution microscopy and fluorescence correlation spectroscopy reveals that small mRNP granules represent mRNA singletons

Mateu-Regue, A.; Christiansen, J.; Bagger, F. O.; Hellriegel, C.; Nielsen, F. C.

10.1101/558098 — molecular biology — Posted on 2019-02-22

670 Ion beam subcellular tomography

Coskun, A. F.; Han, G.; Chen, S.-Y.; Rovira-Clave, X.; Jiang, S.; Schuerch, C. M.; Bai, Y.; Hitzman, C.; Nolan, G. P.

10.1101/557728 — systems biology — Posted on 2019-02-22

671 Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules

Drechsler, M.; Lang, L. F.; Dirks, H.; Burger, M.; Schoenlieb, C.-B.; Palacios, I. M.

10.1101/556043 — cell biology — Posted on 2019-02-22

672 Variation in the Prevalence of Submicroscopic Malaria Infections: Historical Transmission Intensity and Age as Key Determinants

Whittaker, C.; Slater, H. C.; Bousema, T.; Drakeley, C.; Ghani, A.; Okell, L. C.

10.1101/554311 — epidemiology — Posted on 2019-02-22

673 From prevalence to incidence - a new approach in the hospital setting

Willrich, N.; Haller, S.; Eckmanns, T.; Zacher, B.; Karki, T.; Plachouras, D.; Cassini, A.; Suetens, C.; Behnke, M.; Gastmeier, P.; Walter, J.

10.1101/554725 — epidemiology — Posted on 2019-02-22

674 Rabies-induced behavioural changes are key to rabies persistence in dog populations: investigation using a network-based model

Brookes, V. J.; Duerr, S.; Ward, M. P.

10.1101/554451 — epidemiology — Posted on 2019-02-22

675 Genetic risk score for Alzheimer's disease is associated with poor hearing

Brenowitz, W.; Filshtein, T.; Yaffe, K.; Walter, S.; Hoffmann, T.; Jorgenson, E.; Whitmer, R.; Glymour, M. M.

10.1101/556506 — epidemiology — Posted on 2019-02-22

676 Sex and area differences in the association between adiposity and lipid profile in Malawi

Goncalves Soares, A. L.; Banda, L.; Amberbir, A.; Jaffar, S.; Musicha, C.; Price, A.; Nyrienda, M. J.; Lawlor, D. A.; Crampin, A. C.

10.1101/553776 — epidemiology — Posted on 2019-02-22

677 Temporal Trends without Seasonal Effects on Gestational Diabetes Incidence Relate to Reductions in Indices of Insulin Secretion: The Cambridge Baby Growth Study

Petry, C. J.; Fisher, B. G.; Ong, K. K.; Hughes, I. A.; Acerini, C. L.; Dunger, D. B.

10.1101/556886 — epidemiology — Posted on 2019-02-22

678 Educational attainment causally impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study in ~ 780,000 study participants

Rosoff, D. B.; Lohoff, F.

10.1101/557595 — epidemiology — Posted on 2019-02-22

679 Over-activation of BMP signaling in neural crest cells precipitates heart outflow tract septation

Darrigrand, J. F.; Valente, M.; Martinez, P.; Comai, G.; Petit, M.; Nishinakamura, R.; Osorio, D. S.; Ribes, V.; Cadot, B.

10.1101/548511 — developmental biology — Posted on 2019-02-22

680 Pool walking may temporarily improve renal function by suppressing renin-angiotensin-aldosterone system in pregnant women

Yoshihara, T.; Zaitsu, M.; Kubota, S.; Arima, H.; Sasaguri, T.

10.1101/553081 — clinical trials — Posted on 2019-02-22

681 Comparison of three different eye-tracking tasks for distinguishing autistic from typically developing children and autistic symptom severity

Kou, J.; Le, J.; Fu, M.; Lan, C.; Chen, Z.; Li, Q.; Zhao, W.; Xu, L.; Becker, B.; Kendrick, K.

10.1101/547505 — clinical trials — Posted on 2019-02-22

682 singleCellHaystack: Finding surprising genes in 2-dimensional representations of single cell transcriptome data

Vandenbon, A.; Diez, D.

10.1101/557967 — bioinformatics — Posted on 2019-02-22

683 A semi-parametric Bayesian approach, iSBA, for differential expression analysis of RNA-seq data

Bi, R.; Liu, P.

10.1101/558270 — genomics — Posted on 2019-02-22

684 Synthetic gene circuits enable systems-level biosensor discovery at the host-microbe interface

Naydich, A. D.; Nangle, S. N.; Bues, J. J.; Trivedi, D.; Nissar, N.; Inniss, M. C.; Niederhuber, M. J.; Way, J. C.; Silver, P. A.; Riglar, D. T.

10.1101/557934 — synthetic biology — Posted on 2019-02-22

685 Sustained Ca2+ mobilizations: a quantitative approach to predict their importance in cell-cell communication and wound healing

Trinkaus-Randall, V.; Lee, Y.; Kim, M. T.; Rhodes, G.; Sack, K.; Son, S. J.; Rich, C. B.; Kolachalama, V. B.; Gabel, C. V.

10.1101/558320 — cell biology — Posted on 2019-02-22

686 Comparative proteomics of osmotic signal transduction mutants in Botrytis cinerea explain loss of pathogenicity phenotypes and highlight interaction with cAMP and Ca2+ signalling pathways

Kilani, J.; Davanture, M.; Zivy, M.; Fillinger, S.

10.1101/557983 — microbiology — Posted on 2019-02-22

687 Transcriptome analysis reveals that fertilization with cryopreserved sperm downregulates genes relevant for early embryo development in the horse

ORTIZ RODRIGUEZ, J. M.; ORTEGA, C.; GIL, C.; MARTIN CANO, F. E.; GAITSKELL-PHILLIPS, G.; RODRIGUEZ, H.; HINRICHS, K.; Alvarez Barrientos, A.; ROMAN, A.; Pena, F. J.

10.1101/558304 — developmental biology — Posted on 2019-02-22

688 Factors that influence scientific productivity from different countries: A causal approach through multiple regression using panel data

Lancho-Barrantes, B. S.; Ceballos, H. G.; Cantu-Ortiz, F. J.

10.1101/558254 — scientific communication and education — Posted on 2019-02-22

689 PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

ZHANG, F.; Tao, W.; Sun, R.; Wang, J.; Li, C.; Kong, X.; Tian, H.; Ding, Z.

10.1101/558387 — plant biology — Posted on 2019-02-22

690 Dengue and Zika virus 5′-UTRs harbor IRES functions

Song, Y.; Mugavero, J.; Stauft, C. B.; Wimmer, E.

10.1101/557942 — molecular biology — Posted on 2019-02-22

691 Biophotons: low signal/noise ratio reveals crucial events

Benfatto, M.; Pace, E.; Curceanu, C.; Scordo, A.; Clozza, A.; Davoli, I.; Lucci, M.; Francini, R.; De Matteis, F.; Grandi, M.; Tuladhar, R.; Grigolini, P.

10.1101/558353 — biophysics — Posted on 2019-02-22

692 High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers

Orth, K.; Peng, W.; de Souza Santos, M.; Li, Y.; Tomchick, D. R.

10.1101/558338 — biophysics — Posted on 2019-02-22

693 A multi-scale coevolutionary approach to predict interactions between protein domains

Croce, G.; Gueudre, T.; Ruiz Cuevas, M. V.; Keidel, V.; Figliuzzi, M.; Szurmant, H.; Weigt, M.

10.1101/558379 — bioinformatics — Posted on 2019-02-22

694 Hyaluronic acid-functionalized gelatin hydrogels reveal extracellular matrix signals temper the efficacy of erlotinib against patient-derived glioblastoma specimens

Pedron, S.; Wolter, G. L.; Chen, J.-W. E.; Laken, S. E.; Sarkaria, J. N.; Harley, B. A.

10.1101/556324 — bioengineering — Posted on 2019-02-22

695 mRNA adenosine methylase (MTA) deposits m6A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana

Bhat, S. S.; Bielewicz, D.; Grzelak, N.; Gulanicz, T.; Bodi, Z.; Szewc, L.; Bajczyk, M.; Dolata, J.; Smolinski, D. J.; Fray, R. G.; Jarmolowski, A.; Szweykowska-Kulinska, Z.

10.1101/557900 — plant biology — Posted on 2019-02-22

696 Rapid Detection of Burkholderia pseudomallei with a Lateral Flow Recombinase Polymerase Amplification Assay

Peng, Y.; Zheng, X.; Kan, B.; Li, W.; Zhang, W.; Lu, J.; Qin, A.

10.1101/558262 — microbiology — Posted on 2019-02-22

697 A lipid-structured model for macrophage populations in atherosclerotic plaques

Ford, H. Z.; Byrne, H. M.; Myerscough, M. R.

10.1101/557538 — immunology — Posted on 2019-02-22

698 Forest change within and outside protected areas in the Dominican Republic, 2000-2016

Lloyd, J. D.; Leon, Y.

10.1101/558346 — ecology — Posted on 2019-02-22

699 Dynamics of Sox2 expression during rat germ cell development and its relationship with emergence of spermatogonia

Volpato, T.; Tesser, R. B.; Nunes, M.; Stumpp, T.

10.1101/558015 — developmental biology — Posted on 2019-02-22

700 A comparative anatomy of protein crystals: lessons from the automatic processing of 56,000 samples

Svensson, O.; Gilski, M.; Nurizzo, D.; Bowler, M. W.

10.1101/558023 — biophysics — Posted on 2019-02-22

701 Cardiovascular effects of intravenous colforsin in normal and acute respiratory acidosis canine models: a dose-response study

Itami, T.; Hanazono, K.; Oyama, N.; Sano, T.; Yamashita, K.

10.1101/558221 — pharmacology and toxicology — Posted on 2019-02-22

702 Role of DNA methylation dynamics in desiccation and salinity stress responses in rice cultivars

Rajkumar, M. S.; Shankar, R.; Garg, R.; Jain, M.

10.1101/558064 — genomics — Posted on 2019-02-22

703 In silico screen identifies a new Toxoplasma gondii mitochondrial ribosomal protein essential for mitochondrial translation

Lacombe, A.; Maclean, A.; Ovciarikova, J.; Tottey, J.; Sheiner, L.

10.1101/543520 — cell biology — Posted on 2019-02-22

704 Subcellular localization of drug distribution by super-resolution ion beam imaging

Rovira-Clave, X.; Jiang, S.; Chen, S.-Y.; Bai, Y.; Barlow, G. L.; Bhate, S.; Bava, F.-A.; Coskun, A.; Han, G.; Zhu, B.; Ho, C.-M.; Hitzman, C.; Nolan, G.

10.1101/557603 — systems biology — Posted on 2019-02-22

705 Mathematical models incorporating a multi-stage cell cycle explain synchronisation in proliferation experiments

Vittadello, S.; McCue, S.; Gunasingh, G.; Haass, N.; Simpson, M.

10.1101/557702 — biophysics — Posted on 2019-02-22

706 Cardiolipin-dependent Properties of Model Mitochondrial Membranes from Molecular Dynamics Simulations

Wilson, B. A.; Ramanathan, A.; Lopez, C. F.

10.1101/557744 — biophysics — Posted on 2019-02-22

707 Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff

Colon-Thillet, R. S.; Hsieh, E. S.; Graf, L.; McLaughlin, R.; Kochs, G.; Emerman, M. S.; Malik, H. S.

10.1101/557264 — microbiology — Posted on 2019-02-22

708 Genetic and genomic analysis of early abortions in Israeli dairy cattle

Gershoni, M.; Ezra, E.; Weller, J. I.

10.1101/557306 — genomics — Posted on 2019-02-22

709 Women's Decision-Making Autonomy and ICT Utilization on Access to Antenatal Care Services: Survey Results From Jinja and Kampala Cities, Uganda.

Namatovu, H. K.; Oyana, T. J.; Lubega, J. T.

10.1101/557413 — epidemiology — Posted on 2019-02-22

710 Predicting potential current distribution of Lycorma delicatula (Hemiptera: Fulgoridae) using MaxEnt model in South Korea

Namgung, H.; Kim, M.-J.; Baek, S.; Lee, J.-H.; Kim, H.

10.1101/557421 — ecology — Posted on 2019-02-22

711 Mutational burden of hepatoblastomas: a role for the CX3CL1/CX3CR1 chemokine signaling pathway

Aguiar, T.; Prates, M.; Costa, S.; Rodrigues, T.; de Barros, J. S.; Barbosa, A. C.; Maschietto, M.; Valieris, R.; Fernandes, G. R.; Cypriano, M.; de Toledo, S. R. C.; Major, A.; Tojal, I.; Apezzato, M. L. d. P.; Carraro, D. M.; Rosenberg, C.; da Costa, C. M. L.; da Cunha, I. W.; Sarabia, S. F.; Terrada, D.-L.; Krepischi, A. C. V.

10.1101/555466 — cancer biology — Posted on 2019-02-22

712 Programming conventional electron microscopes for solving ultrahigh-resolution structures of small and macro-molecules

Zhou, H.; Luo, F.; Luo, Z.; Li, D.; Liu, C.; Li, X.

10.1101/557827 — biophysics — Posted on 2019-02-22

713 Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice

Ivan, F. X.; Kwoh, C.-K.

10.1101/556647 — bioinformatics — Posted on 2019-02-22

714 Decoupling of timescales reveals sparse convergent CPG network in the adult spinal cord

Radosevic, M.; Willumsen, A.; Petersen, P. C.; Linden, H.; Vestergaard, M.; Berg, R. W.

10.1101/402917 — neuroscience — Posted on 2019-02-21

715 Lemon: a framework for rapidly mining structural information from the Protein Data Bank

Fine, J.; Chopra, G.

10.1101/379891 — bioinformatics — Posted on 2019-02-21

716 Beyond Consensus: Embracing Heterogeneity in Curated Neuroimaging Meta-Analysis

Ngo, G. H.; Eickhoff, S. B.; Nguyen, M.; Sevinc, G.; Fox, P. T.; Spreng, R. N.; Yeo, B. T. T.

10.1101/149567 — neuroscience — Posted on 2019-02-21

717 Nucleotide Archival Format (NAF) enables efficient lossless reference-free compression of DNA sequences

Kryukov, K.; Takahashi Ueda, M.; Nakagawa, S.; Imanishi, T.

10.1101/501130 — bioinformatics — Posted on 2019-02-21

718 Functional ultrasound imaging of deep visual cortex in awake non-human primates

Blaize, K.; Gesnik, M.; Arcizet, F.; Ahnine, H.; Ferrari, U.; Deffieux, T.; Pouget, P.; Chavane, F.; Fink, M.; Sahel, J.-A.; Tanter, M.; Picaud, S.

10.1101/551663 — neuroscience — Posted on 2019-02-21

719 Principles Governing the Dynamics of GABAergic Interneurons in the Barrel Cortex

Yu, J.; Hu, H.; Agmon, A.; Svoboda, K.

10.1101/554949 — neuroscience — Posted on 2019-02-21

720 The intersectional genetics landscape for human

Macedo, A.; Gontijo, A. M.

10.1101/552984 — bioinformatics — Posted on 2019-02-21

721 Mouse model of the human serotonin transporter-linked polymorphic region

Piszczek, L.; Memoli, S.; Raggioli, A.; Viosca, J.; Rientjes, J.; Hublitz, P.; Czaban, W.; Wyrzykowska, A.; Gross, C.

10.1101/556092 — neuroscience — Posted on 2019-02-21

722 Who Bears the Burden of Long-Lived Molecular Biology Databases?

Imker, H. J.

10.1101/552067 — scientific communication and education — Posted on 2019-02-21

723 HEXOKINASE 1 Glycolytic Action Fuels Post-Germinative Seedling Growth

Ganpudi, A.; Romanowski, A.; Halliday, K. J.

10.1101/548990 — plant biology — Posted on 2019-02-21

724 Tracking the emergence of location-based spatial representations

Berens, S. C.; Joensen, B. H.; Horner, A. J.

10.1101/547976 — neuroscience — Posted on 2019-02-21

725 The relationship between neural variability and neural oscillations

Daniel, E.; Meindertsma, T.; Arazi, A.; Donner, T. H.; Dinstein, I.

10.1101/555649 — neuroscience — Posted on 2019-02-21

726 Perinatal Programming of Mucosal Stromal Cell Identity by the Lymphotoxin Pathway Regulates Mucosal Immune Responses in the Adult

Li, C.; Lam, E.; Perez-Shibayama, C.; Lee, D.; Ward, L. A.; Nguyen, A.; Ahmed, M.; Korneev, K. V.; Rojas, O.; Sun, T.; He, H. H.; Martin, A.; Ludewig, B.; Gommerman, J. L.

10.1101/557652 — immunology — Posted on 2019-02-21

727 Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment with TNF-alpha Antagonists

Vaisman-Mentesh, A.; Rosenstein, S.; Yavzori, M.; Dror, Y.; Fudim, E.; Ungar, B.; Kopylov, U.; Picard, O.; Kigel, A.; Ben-Horin, S.; Benhar, I.; Wine, Y.

10.1101/509489 — immunology — Posted on 2019-02-21

728 Genome-wide identification and analysis of A-to-I RNA editing events in the malignantly transformed cell lines from BEP2D induced by α-particles radiation

Liu, Q.; Li, H.; You, L.; Li, T.; Li, L.; Zhou, P.; Bo, X.; Chen, H.; Chen, X.; Hu, Y.

10.1101/551499 — genetics — Posted on 2019-02-21

729 Swapping Birth and Death: Symmetries and Transformations in Phylodynamic Models

Stadler, T.; Steel, M.

10.1101/494583 — evolutionary biology — Posted on 2019-02-21

730 Left-handed fighters are overrepresented and more successful in combat sports

Richardson, T.; Gilman, T.

10.1101/555912 — evolutionary biology — Posted on 2019-02-21

731 ENDOSOMAL MEMBRANE TENSION CONTROLS ESCRT-III-DEPENDENT INTRA-LUMENAL VESICLE FORMATION

Mercier, V.; Larios, J.; Molinard, G.; Goujon, A.; Matile, S.; Gruenberg, J.; Roux, A.

10.1101/550483 — cell biology — Posted on 2019-02-21

732 SLCs contribute to endocrine resistance in breast cancer: role of SLC7A5 (LAT1)

Sevigny, C. M.; Sengupta, S.; Luo, Z.; Liu, X.; Hu, R.; Zhang, Z.; Jin, L.; Pearce, D. A.; Demas, D.; Shajahan-Haq, A. N.; Clarke, R.

10.1101/555342 — cancer biology — Posted on 2019-02-21

733 FISIK: Framework for the Inference of in Situ Interaction Kinetics from single-molecule imaging data

de Oliveira, L. R.; Jaqaman, K.

10.1101/530063 — biophysics — Posted on 2019-02-21

734 Depth-dependent PSF calibration and aberration correction for 3D single-molecule localization

Li, Y.; Wu, Y.-L.; Hoess, P.; Mund, M.; Ries, J.

10.1101/555730 — biophysics — Posted on 2019-02-21

735 OMEGA: a software tool for the management, analysis, and dissemination of intracellular trafficking data that incorporates motion type classification and quality control

Rigano, A.; Galli, V.; Clark, J. M.; Pereira, L. E.; Grossi, L.; Luban, J.; Giulietti, R.; Leidi, T.; Hunter, E.; Valle, M.; Sbalzarini, I. F.; Strambio-De-Castillia, C.

10.1101/251850 — bioinformatics — Posted on 2019-02-21

736 Thermal sensors improve wrist-worn position tracking

Son, J.; Clucas, J.; White, C.; Vogelstein, J.; Milham, M.; Klein, A.

10.1101/552174 — bioinformatics — Posted on 2019-02-21

737 Machine Learning Classification of Attention-Deficit/Hyperactivity Disorder Using Structural MRI Data

Zhang-James, Y.; Helminen, E.; Liu, J.; The ENIGMA-ADHD Working Group, ; Franke, B.; Hoogman, M.; Faraone, S. V.

10.1101/546671 — bioinformatics — Posted on 2019-02-21

738 PRISM: a comprehensive 3D structure database for post-translational modifications and mutations with functional impact

Li, F.; Fan, C.; Marquez-Lago, T. T.; Leier, A.; Revote, J.; Jia, C.; Zhu, Y.; Smith, A. I.; Webb, G. I.; Liu, Q.; Wei, L.; Li, J.; Song, J.

10.1101/523308 — bioinformatics — Posted on 2019-02-21

739 High concentration and yield production of mannose from acai (Euterpe oleracea) seeds via diluted-acid and mannanase-catalyzed hydrolysis

Ferreira Monteiro, A.; Santos Miguez, I.; Pedro Rodrigues Barros Silva, J.; Santana Silva, A.

10.1101/513168 — biochemistry — Posted on 2019-02-21

740 Estimating statistical significance of local protein profile-profile alignments

Margelevicius, M.

10.1101/484485 — bioinformatics — Posted on 2019-02-21

741 From predictive models to cognitive models: An analysis of rat behavior in the two-armed bandit task

Miller, K. J.; Botvinick, M. M.; Brody, C. D.

10.1101/461129 — animal behavior and cognition — Posted on 2019-02-21

742 Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice

Bhandare, A.; Huckstepp, R.; Dale, N.

10.1101/492041 — neuroscience — Posted on 2019-02-21

743 No cell is an island: circulating T cell:monocyte complexes are markers of immune perturbations

Burel, J. G.; Pomaznoy, M.; Lindestam Arlehamn, C. S.; Weiskopf, D.; da Silva Antunes, R.; Jung, Y.; Schulten, V.; Babor, M.; Seumois, G.; Greenbaum, J. A.; Premawansa, S.; Premawansa, G.; Wijewickrama, A.; Vidanagama, D.; Gunasena, B.; Tippalagama, R.; deSilva, A. D.; Gilman, R. H.; Saito, M.; Taplitz, R.; Ley, K.; Vijayanand, P.; Sette, A.; Peters, B.

10.1101/411553 — immunology — Posted on 2019-02-21

744 IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation

Zumaquero, E.; Stone, S. L.; Scharer, C. D.; Jenks, S. A.; Nellore, A.; Mousseau, B.; Rosal-Vela, A.; Botta, D.; Bradley, J. E.; Wojciechowski, W.; Ptacek, T.; Danila, M. I.; Edberg, J. C.; Bridges, S. L.; Kimberly, R. P.; Chatham, W. W.; Schoeb, T. R.; Rosenberg, A.; Boss, J. M.; Sanz, I.; Lund, F. E.

10.1101/557520 — immunology — Posted on 2019-02-21

745 MAP7 recruits kinesin-1 to microtubules to direct organelle transport

Chaudhary, A. R.; Lu, H.; Krementsova, E. B.; Bookwalter, C. S.; Trybus, K. M.; Hendricks, A. G.

10.1101/557611 — biophysics — Posted on 2019-02-21

746 Seeing, fast and slow: the effects of processing time on perceptual bias

Dekel, R.; Sagi, D.

10.1101/556944 — neuroscience — Posted on 2019-02-21

747 Marine deep biosphere microbial communities assemble in near-surface sediments in Aarhus Bay

Petro, C.; Zaencker, B.; Starnawski, P.; Jochum, L. M.; Ferdelman, T. G.; Jorgensen, B. B.; Roy, H.; Kjeldsen, K. U.; Schramm, A.

10.1101/557041 — microbiology — Posted on 2019-02-21

748 Genome-wide data for effective conservation of manta and devil ray species

Hosegood, J.; Humble, E.; Ogden, R.; de Bruyn, M.; Creer, S.; Stevens, G.; Abudaya, M.; Bassos-Hull, K.; Bonfil, R.; Fernando, D.; Foote, A. D.; Hipperson, H.; Jabado, R. W.; Kaden, J.; Moazzam, M.; Peel, L.; Pollett, S.; Ponzo, A.; Poortvliet, M.; Salah, J.; Senn, H.; Stewart, J.; Wintner, S.; Carvalho, G.

10.1101/458141 — genomics — Posted on 2019-02-21

749 Genetic Diversity and Phylogenetic Relationships of Annual and Perennial Glycine Species

Hwang, E.-Y.; Wei, H.; Schroeder, S.; Fickus, E.; Quigley, C.; Elia, P.; Costa, L.; Araya, S.; Ferreira, M.; Cregan, P.; Song, Q.

10.1101/557439 — genetics — Posted on 2019-02-21

750 Male evolution under relaxed selection: Evidence for degeneration in sperm produced by male snails from asexual lineages

Jalinsky, J.; Logsdon, J. M.; Neiman, M.

10.1101/556357 — evolutionary biology — Posted on 2019-02-21

751 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies

Avila, P.; Fromhage, L.; Lehmann, L.

10.1101/454512 — evolutionary biology — Posted on 2019-02-21

752 Centrosomes control kinetochore-fiber plus-end dynamics via HURP to ensure symmetric divisions

Dudka, D.; Liaudet, N.; Vassal, H.; Meraldi, P.

10.1101/557058 — cell biology — Posted on 2019-02-21

753 HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly.

Favard, C.; Chojnacki, J.; Merida, P.; Yandrapalli, N.; Mak, J.; Eggeling, C.; Muriaux, D.

10.1101/556308 — biophysics — Posted on 2019-02-21

754 Deciphering the structural intricacy in virulence effectors for proton-motive force mediated unfolding and type-III protein secretion

Khanppnavar, B.; Roy, A.; Chandra, K.; Maiti, N. C.; Datta, S.

10.1101/557496 — biophysics — Posted on 2019-02-21

755 PRODIGY: personalized prioritization of driver genes

Dinstag, G.; Shamir, R.

10.1101/456723 — bioinformatics — Posted on 2019-02-21

756 Bacterial defiance as a form of prodrug failure

Holt, B. A.; Kwong, G. A.

10.1101/556951 — bioengineering — Posted on 2019-02-21

757 Testosterone mediates status-specific patterns of cooperation and transmission of behavior in a social network

Ryder, T. B.; Dakin, R.; Vernasco, B. J.; Evans, B. S.; Horton, B. M.; Moore, I. T.

10.1101/453548 — animal behavior and cognition — Posted on 2019-02-21

758 Using extracellular low frequency signals to improve the spike sorting of cerebellar complex spikes

Zur, G.; Joshua, M.

10.1101/556985 — neuroscience — Posted on 2019-02-21

759 Impact of historical and current features of the cityscape on the genetic structure of the house mouse (Mus musculus domesticus) in Dakar (Senegal, West Africa)

Stragier, C.; Piry, S.; Loiseau, A.; Kane, M.; Sow, A.; Niang, Y.; Diallo, M.; Ndiaye, A.; Gauthier, P.; Borderon, M.; Granjon, L.; Brouat, C.; Berthier, K.

10.1101/557066 — ecology — Posted on 2019-02-21

760 Spatiotemporal empirical mode decomposition of resting-state fMRI signals: application to global signal regression

Moradi, N.; Dousty, M.; Sotero, R.

10.1101/556555 — neuroscience — Posted on 2019-02-21

761 Structural and biochemical studies of an NB-ARC domain from a plant NLR immune receptor

Steele, J. F.; Hughes, R. K.; Banfield, M. J.

10.1101/557280 — plant biology — Posted on 2019-02-21

762 Manipulating patterns of dynamic deformation elicits the impression of cloth with varying stiffness

Bi, W.; Jin, P.; Nienborg, H.; Xiao, B.

10.1101/556530 — neuroscience — Posted on 2019-02-21

763 Polymodal Sensory Thalamic Inputs to the Rat Lateral Amygdala are Facilitated by Chronic Ethanol Exposure and Regulate Withdrawal-associated Anxiety

Morales, M.; McGinnis, M. M.; Chappell, A. M.; Parrish, B. C.; McCool, B. A.

10.1101/557256 — neuroscience — Posted on 2019-02-21

764 Unification of optimal targeting methods in Transcranial Electrical Stimulation

Fernandez Corazza, M.; Turovets, S.; Muravchik, C. H.

10.1101/557090 — bioengineering — Posted on 2019-02-21

765 Is testosterone responsible for athletic success in female athletes?

Ahmetov, I. I.; Roos, T. R.; Stepanova, A. A.; Biktagirova, E. M.; Semenova, E. A.; Shchuplova, I. S.; Bets, L. V.

10.1101/557348 — biochemistry — Posted on 2019-02-21

766 FERMI: A novel method for sensitive detection of rare mutations in somatic tissue

Liggett, L. A.; Sharma, A.; De, S.; DeGregori, J.

10.1101/208066 — genetics — Posted on 2019-02-21

767 Condition-dependent SOD activity attenuates morph-specific superoxide effects on sperm performance

Friesen, C.; de Graaf, S. P.; Olsson, M.

10.1101/556548 — evolutionary biology — Posted on 2019-02-21

768 Developmental changes in the processing of faces as revealed by EEG decoding

Mares, I.; Ewing, L.; Farran, E. K.; Smith, F. W.; Smith, M. L.

10.1101/557447 — neuroscience — Posted on 2019-02-21

769 Head MagnetoMyography (hMMG): a novel approach to monitor face and whole-head muscular activity

Barchiesi, G.; Demarchi, G.; Wilhelm, F.; Hauswald, A.; Sanchez, G.; Weisz, N.

10.1101/556100 — neuroscience — Posted on 2019-02-21

770 Delta and theta neural entrainment during phonological and semantic processing in speech perception

Mai, G.; Wang, W. S.-Y.

10.1101/556837 — neuroscience — Posted on 2019-02-21

771 Identifying cortical substrates underlying the phenomenology of stereopsis and realness: A pilot fMRI study

Uji, M.; Lingnau, A.; Cavin, I.; Vishwanath, D.

10.1101/557157 — neuroscience — Posted on 2019-02-21

772 Protection of phage applications in crop production: a patent landscape.

Holtappels, D.; Lavigne, R.; Huys, I.; Wagemans, J.

10.1101/555904 — microbiology — Posted on 2019-02-21

773 Thermal sensors improve wrist-worn position tracking

Son, J.; Clucas, J.; White, C.; Vogelstein, J.; Milham, M.; Klein, A.

10.1101/552174 — bioinformatics — Posted on 2019-02-21

774 Novel transcriptome-based polygenic risk score for depression is associated with neural processing of social stimuli

Mareckova, K.; Hawco, C.; Bakht, A.; Calarco, N.; Voineskos, A. N.; Sibille, E.; Hariri, A. R.; Nikolova, Y.

10.1101/556852 — neuroscience — Posted on 2019-02-21

775 BKV clearance time correlates with exhaustion state and T-cell receptor repertoire shape of BKV-specific T-cells in renal transplant patients

Stervbo, U.; Nienen, M.; Weist, B. J.; Kuchenbecker, L.; Wehler, P.; Westhoff, T. H.; Reinke, P.; Babel, N.

10.1101/556829 — immunology — Posted on 2019-02-21

776 ILT7 activation and plasmacytoid dendritic cell response are governed by BST2 determinants that are structurally-distinct

Bego, M. G.; Miguet, N.; Laliberte, A.; Aschman, N.; Gerard, F.; Merakos, A. A.; Weissenhorn, W.; Cohen, E. A.

10.1101/557116 — immunology — Posted on 2019-02-21

777 The effect of environmental enrichment on behavioral variability depends on genotype, behavior, and type of enrichment

Akhund-Zade, J.; Ho, S.; O'Leary, C.; de Bivort, B. L.

10.1101/557181 — genetics — Posted on 2019-02-21

778 Characterisation of the genetic architecture underlying eye size variation within Drosophila melanogaster and Drosophila simulans

Gaspar, P.; Arif, S.; Sumner-Rooney, L.; Kittelmann, M.; Stern, D. L.; Nunes, M. D. S.; McGregor, A. P.

10.1101/555698 — evolutionary biology — Posted on 2019-02-21

779 A Machine Learning Approach for Long-Term Prognosis of Bladder Cancer based on Clinical and Molecular Features

Song, Q.; Seigne, J.; Schned, A.; Kelsey, K.; Karagas, M.; Hassanpour, S.

10.1101/557470 — bioinformatics — Posted on 2019-02-21

780 The milk protein alpha-casein suppresses triple negative breast cancer stem cell activity via STAT and HIF-1alpha signalling pathways in breast cancer cells and fibroblasts

Garner, K. E.; Lamb, R.; Sims, A. H.; Clarke, R. B.

10.1101/557355 — cancer biology — Posted on 2019-02-21

781 Excitatory and inhibitory intracortical circuits for orientation and direction selectivity

Rossi, L. F.; Harris, K.; Carandini, M.

10.1101/556795 — neuroscience — Posted on 2019-02-21

782 Differences in functional connectivity along the anterior-posterior axis of human hippocampal subfields

Dalton, M. A.; McCormick, C.; Maguire, E. A.

10.1101/410720 — neuroscience — Posted on 2019-02-21

783 A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium

Nassir, N.; Hyde, G. J.; Baskar, R.

10.1101/556977 — developmental biology — Posted on 2019-02-21

784 ACValidator: a novel assembly-based approach for in silico validation of circular RNAs

Sekar, S.; Geiger, P.; Adkins, J.; Serrano, G.; Beach, T.; Liang, W. S.

10.1101/556597 — bioinformatics — Posted on 2019-02-21

785 Modulation of Insr and insulin receptor signaling by hyperinsulinemia in vitro and in vivo

Cen, H.; Botezelli, J. D.; Johnson, J. D.

10.1101/556571 — physiology — Posted on 2019-02-21

786 A neuromechanistic model for rhythmic beat generation

Bose, A.; Byrne, A.; Rinzel, J.

10.1101/397075 — neuroscience — Posted on 2019-02-21

787 New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

Bassaganyas, L.; Popa, S. J.; Horlbeck, M.; Ashok, A.; Stewart, S. E.; Butnaru, C. M.; Brouwers, N.; Heydari, K.; Ripoche, J.; Weissman, J.; Schekman, R.; Malhotra, V.; Moreau, K.; Villeneuve, J.

10.1101/556746 — cell biology — Posted on 2019-02-21

788 TGFβ signaling curbs cell fusion and muscle regeneration

Girardi, F.; Taleb, A.; Giordani, L.; CADOT, B.; Datye, A.; Ebrahimi, M.; Gamage, D. G.; Millay, D. P.; Gilbert, P. M.; Le Grand, F.

10.1101/557009 — cell biology — Posted on 2019-02-21

789 Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies

Chang, W. H.; Lai, A. G.

10.1101/556878 — cancer biology — Posted on 2019-02-21

790 Discovery of tandem and interspersed segmental duplications using high throughput sequencing

Soylev, A.; Le, T.; Amini, H.; Alkan, C.; Hormozdiari, F.

10.1101/393694 — bioinformatics — Posted on 2019-02-21

791 A functional landscape of chronic kidney disease entities from public transcriptomic data

Tajti, F.; Kuppe, C.; Antoranz, A.; Ibrahim, M. M.; Kim, H.; Ceccarelli, F.; Holland, C.; Olauson, H.; Floege, J.; Alexopoulos, L. G.; Kramann, R.; Saez-Rodriguez, J.

10.1101/265447 — pathology — Posted on 2019-02-21

792 Using machine learning-based lesion behavior mapping to identify anatomical networks of cognitive dysfunction: spatial neglect and attention

Wiesen, D.; Sperber, C.; Yourganov, G.; Rorden, C.; Karnath, H.-O.

10.1101/556753 — neuroscience — Posted on 2019-02-21

793 Positive selection in the Ebola virus proteome

Dasmeh, P.

10.1101/556910 — genomics — Posted on 2019-02-21

794 Ancient tropical extinctions contributed to the latitudinal diversity gradient

Meseguer, A. S.; Condamine, F. L.

10.1101/236646 — evolutionary biology — Posted on 2019-02-21

795 A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia demonstrates cancer-crosstalk with stroma to impair normal tissue function

Baryawno, N.; Przybylski, D.; Kowalczyk, M.; Kfoury, Y.; Severe, N.; Gustafsson, K.; Francois, M.; Tabaka, M.; Hofree, M.; Dionne, D.; Papazian, A.; Lee, D.; Rozenblatt-Rosen, O.; Regev, A.; Scadden, D.

10.1101/556845 — cell biology — Posted on 2019-02-21

796 A metal-dependent switch moderates activity of the hexameric M17 aminopeptidases.

Drinkwater, N.; Yang, W.; Riley, B. T.; Hayes, B. K.; Kannan Sivaraman, K.; Malcolm, T. R.; Atkinson, S. C.; Borg, N. A.; Kass, I.; Buckle, A. M.; McGowan, S.

10.1101/244665 — biochemistry — Posted on 2019-02-21

797 Association Between The Posterior Part Of The Circle Of Willis And Vertebral Artery Hypoplasia

Gaigalaite, V.; Dementaviciene, J.; Vilimas, A.; Kalibatiene, D.

10.1101/557397 — neuroscience — Posted on 2019-02-21

798 Flooding and hydrologic connectivity modulate community assembly in a dynamic river-floodplain ecosystem

Larsen, s.; Karaus, U.; Claret, C.; Sporka, F.; Hamerlik, L.; Tockner, K.

10.1101/557405 — ecology — Posted on 2019-02-21

799 Knowledge Gaps of STIs in Africa; Systematic review

Suluiman, M.; Salah-Eldin, M. A.; Idris, A. B.; Hasabo, E. A.; Osman, Z. H.; Osman, W. M.

10.1101/557389 — microbiology — Posted on 2019-02-21

800 Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

Sorlie, T.; Fougner, C.; Bergholtz, H.; Kuiper, R.; Norum, J. H.

10.1101/557298 — genomics — Posted on 2019-02-21

801 Evolution of interface binding strengths in simplified model of protein quaternary structure

Leonard, A. S.; Ahnert, S. E.

10.1101/557272 — evolutionary biology — Posted on 2019-02-21

802 Can early assessment of hand grip strength in elderly hip fracture patients predict functional outcome?

Selakovic, I.; Dubljanin-Raspopovic, E.; Markovic-Denic, L.; Marusic, V.; Cirkovic, A.; Kadija, M.; Tomanovic-Vujadinovic, S.; Tulic, G.

10.1101/557371 — epidemiology — Posted on 2019-02-21

803 Spatial Correlation and Breast Cancer Risk

Fowler, E. E.; Hathaway, C.; Tillman, F.; Weinfurtner, R.; Sellers, T. A.; Heine, J.

10.1101/555136 — bioengineering — Posted on 2019-02-21

804 synthesis and characterization of pH-sensitive nanocomposite based on natural polymer -sodium alginate- extracted from marine brown alga Sargassum asperifolium collected from Jazan Coasts, KSA.

Mohamed, s. F.; Agili, F. A.

10.1101/557231 — synthetic biology — Posted on 2019-02-21

805 Longitudinal Study on Ocular Manifestations in a Cohort of Patients with Fabry Disease

Michaud, L.

10.1101/557207 — pathology — Posted on 2019-02-21

806 The opportunistic pathogen Stenotrophomonas maltophilia utilizes a type IV secretion system for interbacterial killing

Bayer-Santos, E.; Cenens, W.; Matsuyama, B. Y.; Di Sessa, G.; Mininel, I. D. V.; Farah, C. S.

10.1101/557322 — microbiology — Posted on 2019-02-21

807 30 years of satellite data show imperiled species are most vulnerable to habitat loss on private lands

Evans, M. J.; Eichenwald, A. J.; Malcom, J. W.

10.1101/556241 — ecology — Posted on 2019-02-21

808 High sampling effectiveness for non-bee pollinators using vane traps in both open and wooded habitats

Hall, M. A.; Reboud, E. L.

10.1101/556498 — ecology — Posted on 2019-02-21

809 Effect of Maxillary Expansion and Protraction on the Oropharyngeal Airway in Individuals with Non-syndromic Cleft Palate with or without Cleft Lip

Oberoi, S.; Alrejaye, N.; Gao, J.

10.1101/557199 — physiology — Posted on 2019-02-21

810 Orally consumed cannabinoids provide long-lasting relief of allodynia in a mouse model of chronic neuropathic pain

Leung, E. J. Y.; Abraham, A. D.; Wong, B. A.; Kruse, L. C.; Clark, J. J.; Land, B. B.

10.1101/556373 — pharmacology and toxicology — Posted on 2019-02-21

811 The dopamine receptor D5 gene shows signs of independent erosion in Toothed and Baleen whales

Alves, L. Q.; Alves, J.; Ribeiro, R.; Ruivo, R.; Castro, L. F.

10.1101/556035 — evolutionary biology — Posted on 2019-02-21

812 Protective role of the deSUMOylating enzyme SENP3 in myocardial ischaemia-reperfusion injury

Rawlings, N.; Lee, L.; Nakamura, Y.; Wilkinson, K.; Henley, J.

10.1101/557249 — cell biology — Posted on 2019-02-21

813 Programmable patterns in a DNA-based reaction-diffusion system

Chen, S.; Seelig, G.

10.1101/556381 — synthetic biology — Posted on 2019-02-21

814 Noradrenergic signaling in wakeful states inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex.

Stowell, R. D.; Sipe, G. O.; Dawes, R. P.; Batchelor, H. N.; Lordy, K. A.; Bidlack, J. M.; Brown, E.; Sur, M.; Majewska, A. K.

10.1101/556480 — neuroscience — Posted on 2019-02-21

815 An open-source platform to distribute and interpret data from multiplexed assays of variant effect

Esposito, D.; Weile, J.; Shendure, J.; Starita, L. M.; Papenfuss, A. T.; Roth, F. P.; Fowler, D. M.; Rubin, A. F.

10.1101/555797 — genomics — Posted on 2019-02-21

816 Rethinking the fundamental unit of ecological remote sensing: Estimating individual level plant traits at scale

Marconi, S.; Graves, S.; Weinstein, B.; Bohlman, S.; White, E.

10.1101/556472 — ecology — Posted on 2019-02-21

817 The COMPARE Data Hubs

Amid, C.; Pakseresht, N.; Silvester, N.; Jayathilaka, S.; Lund, O.; Dynovski, L. D.; Pataki, B. A.; Visontai, D.; Cotten, M.; Xavier, B. B.; Alako, B.; Belka, A.; Cisneros, J. J. L.; Haringhuizen, G. B.; Harrison, P. W.; Hoeper, D.; Holt, S.; Hundahl, C.; Hussein, A.; Kaas, R. S.; Malhotra-Kumar, S.; Leinonen, R.; Nieuwenhuijse, D. F.; Rahman, N.; dos S Ribeiro, C.; Skiby, J. E.; Steger, J.; Szalai-Gindl, J. M.; Thomsen, M. C. F.; Csabai, I.; Koopmans, M.; Aarestrup, F.; Cochrane, G.

10.1101/555938 — bioinformatics — Posted on 2019-02-21

818 Murburn concept explains the acutely lethal effect of cyanide

Manoj, K. M.

10.1101/555888 — biochemistry — Posted on 2019-02-21

819 Deep coverage microscopy exposes a pharmacological window for modifiers of neuronal network connectivity

Verschuuren, M.; Verstraelen, P.; Garcia, G.; Cilissen, I.; Coninx, E.; Verslegers, M.; Larsen, P.; Nuydens, R.; De Vos, W. H.

10.1101/555714 — neuroscience — Posted on 2019-02-21

820 Lifeless Clostridia stimulate methanogenesis on Fe0 in an urban lake corrosive community

Palacios Jaramillo, P. A.; Rotaru, A.-E.

10.1101/556704 — microbiology — Posted on 2019-02-21

821 Adrenergic signaling in muscularis macrophages limits neuronal death following enteric infection

Matheis, F.; Muller, P. A.; Graves, C. L.; Gabanyi, I.; Kerner, Z. J.; Costa-Borges, D.; Mucida, D.

10.1101/556340 — immunology — Posted on 2019-02-21

822 Estimating the abundance of duiker (Cephalophus spp.) populations in African rainforests: an overview of relevant methods

Elenga, G. B. E.; Gaillard, J.-M.; Musibono, D. E. A.; Ifuta, S. N. B.; Bonenfant, C.

10.1101/556332 — ecology — Posted on 2019-02-21

823 Adult emergence order in a community of cavity-nesting bees and wasps, and their parasites

MacIvor, S.

10.1101/556456 — ecology — Posted on 2019-02-21

824 locBLAST v2.0 - an improved PHP library for embedding standalone NCBI BLAST+ program to an interactive graphical user interface

Ashok Kumar, T.

10.1101/556225 — bioinformatics — Posted on 2019-02-21

825 pyKNEEr: An image analysis workflow for open and reproducible research on femoral knee cartilage

Bonaretti, S.; Gold, G. E.; Beaupre, G. S.

10.1101/556423 — bioengineering — Posted on 2019-02-21

826 Body coloration and mechanisms of colour production in Archelosauria: The case of deirocheline turtles

Brejcha, J.; Bataller, J. V.; Bosakova, Z.; Geryk, J.; Havlikova, M.; Kleisner, K.; Marsik, P.; Font, E.

10.1101/556670 — zoology — Posted on 2019-02-21

827 Sensory neuron-derived Nav1.7 contributes to dorsal horn neuron excitability

Alles, S. R. A.; Nascimento, F.; Lujan, R.; Millet, Q.; Santana, S.; Bangash, A.; Cox, J.; Beato, M.; Zhao, J.; Wood, J.

10.1101/551747 — neuroscience — Posted on 2019-02-21

828 Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

Clarke, T.-K.; Adams, M.; Howard, D. M.; Xia, C.; Davies, G.; Hayward, C.; Campbell, A.; Padmanabhan, S.; Smith, B.; Murray, A.; Porteous, D.; Deary, I.; McIntosh, A.

10.1101/555961 — genetics — Posted on 2019-02-21

829 Left-handed fighters are overrepresented in combat sports and are better fighters

Richardson, T.; Gilman, T.

10.1101/555912 — evolutionary biology — Posted on 2019-02-21

830 Oxidation state dependent conformational changes of HMGB1 regulates the formation of the CXCL12/HMGB1 heterocomplex

Fassi, E. M. A.; Sgrignani, J.; D'Agostino, G.; Cecchinato, V.; Garfalo, M.; Grazioso, G.; Uguccioni, M.; Cavalli, A.

10.1101/555946 — biochemistry — Posted on 2019-02-21

831 Aging alters the role of basolateral amygdala in intertemporal choice

Hernandez, C. M.; Orsini, C. A.; Labiste, C.; Wheeler, A.-R.; Ten Eyck, T. W.; Bruner, M. M.; Sahagian, T. J.; Harden, S. W.; Frazier, C. J.; Setlow, B.; Bizon, J. L.

10.1101/556894 — neuroscience — Posted on 2019-02-21

832 Ovarian cancer G protein-coupled receptor 1 inhibits A549 cells Migration through Casein kinase 2α intronless gene and Neutral endopeptidase

Sharma, A. L.; Meeitei, P. M.; Singh, N. T.; Singh, T. R.; Shanjukumar Singh, L.

10.1101/556720 — cancer biology — Posted on 2019-02-21

833 3D cell culture stimulates the secretion of in vivo like exosomes

Thippabhotla, S.; Wei, L.; Zhong, C.; He, M.

10.1101/556621 — bioengineering — Posted on 2019-02-21

834 Effector loading onto VgrG spike proteins is critical for the assembly of the type VI secretion system in Agrobacterium tumefaciens

Lien, Y.-W.; Wu, C.-F.; Bondage, D.; Lin, J.-S.; Shih, Y.-L.; Chang, J.; Lai, E.-M.

10.1101/556712 — microbiology — Posted on 2019-02-21

835 Treatment-shortening effect of a novel regimen combining high-dose rifapentine and clofazimine in pathologically distinct mouse models of tuberculosis

Saini, V.; Ammerman, N. C.; Chang, Y. S.; Tasneen, R.; Chaisson, R.; Jain, S. K.; Nuermburger, E.; Grosset, J. H.

10.1101/556654 — microbiology — Posted on 2019-02-21

836 Developmental plasticity in metabolism but not in energy reserve accumulation in a seasonally polyphenic butterfly

Kivelä, S.; Gotthard, K.; Lehmann, P.

10.1101/556969 — evolutionary biology — Posted on 2019-02-21

837 PhoX - an IMAC-enrichable Crosslinking Reagent

Steigenberger, B. A.; Pieters, R. J.; Heck, A. J. R.; Scheltema, R. A.

10.1101/556688 — biochemistry — Posted on 2019-02-21

838 Direct Effects of Cigarette Smoke in Pulmonary Arterial Cells alter Vascular Tone through Arterial Remodeling and Kv7.4 Channel Dysregulation.

Sevilla-Montero, J.; Labrousse-Arias, D.; Fernandez-Perez, C.; Barreira, B.; Mondejar-Parreno, G.; Cogolludo, A.; Calzada, M. J.

10.1101/555953 — cell biology — Posted on 2019-02-21

839 Myc instructs and maintains pancreatic adenocarcinoma phenotype

Sodir, N. M.; Kortlever, R. M.; Barthet, V. J.; Pellegrinet, L.; Campos, T.; Kupczak, S.; Brown Swigart, L.; Soucek, L.; Arends, M. J.; Littlewood, T. D.; Evan, G. I.

10.1101/556399 — cancer biology — Posted on 2019-02-21

840 Microfluidic protein isolation and sample preparation for high resolution cryo-EM

Schmidli, C.; Albiez, S.; Rima, L.; Righetto, R.; Mohammed, I.; Oliva, P.; Kovacik, L.; Stahlberg, H.; Braun, T.

10.1101/556068 — biophysics — Posted on 2019-02-21

841 Structural Insights into Hearing Loss Genetics from Polarizable Protein Repacking

Tollefson, M. R.; Litman, J.; Qi, G.; Marini, R. J.; O'Connell, C. E.; Wipfler, M. J.; Bernabe, H. V.; Tollefson, W. T.; Casavant, T. L.; Braun, T. A.; Smith, R. J.; Schnieders, M. J.

10.1101/556258 — biophysics — Posted on 2019-02-21

842 The role of SLC7A5 (LAT1) in endocrine therapy resistant breast cancer

Sevigny, C. M.; Sengupta, S.; Luo, Z.; Liu, X.; Hu, R.; Zhang, Z.; Jin, L.; Pearce, D. A.; Demas, D.; Shajahan-Haq, A. N.; Clarke, R.

10.1101/555342 — cancer biology — Posted on 2019-02-21

843 Max deletion destabilizes MYC protein and abrogates Eμ-Myc lymphomagenesis

Mathsyaraja, H.; Freie, B.; Cheng, P.-F.; Babaeva, E.; Janssens, D.; Henikoff, S.; Eisenman, R. N.

10.1101/556522 — cancer biology — Posted on 2019-02-21

844 Disrupted mechanobiology links the molecular and cellular phenotypes in familial dilated cardiomyopathy

Clippinger, S. R.; Cloonan, P. E.; Greenberg, L.; Ernst, M.; Stump, W. T.; Greenberg, M. J.

10.1101/555391 — biophysics — Posted on 2019-02-21

845 Depth-dependent PSF calibration and aberration correction for 3D single-molecule localization

Li, Y.; Wu, Y.-L.; Hoess, P.; Mund, M.; Ries, J.

10.1101/555730 — biophysics — Posted on 2019-02-21

846 CDK1 dependent phosphorylation of hTERT contributes to cancer progression

Yasukawa, M.; Ando, Y.; Yamashita, T.; Matsuda, Y.; Shoji, S.; Morioka, M. S.; Kawaji, H.; Shiozawa, K.; Abe, T.; Yamada, S.; Kaneko, M. K.; Kato, Y.; Furuta, Y.; Kondo, T.; Shirouzu, M.; Hayashizaki, Y.; Kaneko, S.; Masutomi, K.

10.1101/556514 — cancer biology — Posted on 2019-02-21

847 Considerations for clinical curation, classification and reporting of low-penetrance and low effect size variants associated with disease risk

Senol-Cosar, O.; Schmidt, R. J.; Qian, E.; Hoskinson, D.; Mason-Suares, H.; Funke, B.; Lebo, M. S.

10.1101/556316 — genetics — Posted on 2019-02-20

848 Ancient whole genome duplications and the evolution of the gene duplication and loss rate

Zwaenepoel, A.; Van de Peer, Y.

10.1101/556076 — evolutionary biology — Posted on 2019-02-20

849 Microbial metabolites mediate bumble bee attraction and feeding

Schaeffer, R. N.; Rering, C. C.; Maalouf, I.; Beck, J. J.; Vannette, R. L.

10.1101/549279 — ecology — Posted on 2019-02-20

850 Empowering the annotation and discovery of structured RNAs with scalable and accessible integrative clustering

Miladi, M.; Sokhoyan, E.; Houwaart, T.; Heyne, S.; Costa, F.; Gruening, B.; Backofen, R.

10.1101/550335 — bioinformatics — Posted on 2019-02-20

851 Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Moudgil, A.; Wilkinson, M. N.; Chen, X.; He, J.; Cammack, A. J.; Vasek, M. J.; Lagunas, T.; Qi, Z.; Morris, S. A.; Dougherty, J. D.; Mitra, R. D.

10.1101/538553 — genomics — Posted on 2019-02-20

852 Transcriptome stability profiling identifies novel and functional MIRNA targets in melanoma cells

Joshi, P.; Seki, T.; Kitamura, S.; Bergano, A.; Lee, B.; Perera, R. J.

10.1101/555540 — cancer biology — Posted on 2019-02-20

853 Microstructure of Ingestive Behaviors in Mus Musculus

Onnis, G.; Layco-Bader, E.; Tecott, L.

10.1101/529198 — animal behavior and cognition — Posted on 2019-02-20

854 Transposon-mediated, cell type-specific transcription factor recording in the mouse brain

Cammack, A. J.; Moudgil, A.; Lagunas, T.; Vasek, M. J.; Shabsovich, M.; He, J.; Chen, X.; Hooda, M.; Wilkinson, M. N.; Miller, T. M.; Mitra, R. D.; Dougherty, J. D.

10.1101/538504 — neuroscience — Posted on 2019-02-20

855 Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

Adams, M. J.; Howard, D. M.; Luciano, M.; Davies, G. M.; Hill, W. D.; 23andMe Research Team, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Smith, D. J.; Deary, I. J.; Porteous, D. J.; McIntosh, A. M.

10.1101/547828 — genetics — Posted on 2019-02-20

856 Anticipation of a serial transfer protocol through the evolution of fine-tuned growth dynamics

van Dijk, B.; Meijer, J.; Cuypers, T. D.; Hogeweg, P.

10.1101/554766 — evolutionary biology — Posted on 2019-02-20

857 Myosin Orientation in a Muscle Fiber Determined with High Angular Resolution Using Bifunctional Spin Labels

Savich, Y.; Binder, B. P.; Thompson, A. R.; Thomas, D. D.

10.1101/513556 — biophysics — Posted on 2019-02-20

858 An unusual nucleosomal sequence pattern is enriched in mammalian genes

Wright, G. M.; Cui, F.

10.1101/207167 — bioinformatics — Posted on 2019-02-20

859 Context-specific modulation of intrinsic coupling modes shapes multisensory processing

Galindo Leon, E. E.; Stitt, I.; Pieper, F.; Stieglitz, T.; Engler, G.; Engel, A. K.

10.1101/509943 — neuroscience — Posted on 2019-02-20

860 Addressing reverse inference in structural brain alterations

Cauda, F.; Nani, A.; Liloia, D.; Manuello, J.; Premi, E.; Duca, S.; Fox, P.; Costa, T.

10.1101/536847 — neuroscience — Posted on 2019-02-20

861 Relationships between depressive symptoms and brain responses during emotional movie viewing emerge in adolescence

Gruskin, D. C.; Rosenberg, M. D.; Holmes, A. J.

10.1101/542720 — neuroscience — Posted on 2019-02-20

862 Sex-biased gene expression is repeatedly masculinized in asexual females

Parker, D. J.; Bast, J.; Jalvingh, K.; Dumas, Z.; Robinson-Rechavi, M.; Schwander, T.

10.1101/553172 — evolutionary biology — Posted on 2019-02-20

863 High-definition transcranial direct current stimulation over the dorsal premotor cortex modulates motor network excitability

Lefebvre, S.; Jann, K.; Schmiesing, A.; Ito, K.; Jog, M.; Qiao, Y.; Cabeen, R.; Shi, Y.; Schweighofer, N.; Wang, D. J.; Liew, S.-L.

10.1101/487488 — neuroscience — Posted on 2019-02-20

864 An insect serotonin receptor mediates cellular immune responses and its inhibition by phenylethylamide derivatives from bacterial secondary metabolites

Kim, Y.; Hasan, A.; Yeom, H.-S.; Ryu, J.; Bode, H.

10.1101/556159 — immunology — Posted on 2019-02-20

865 Adapting genotyping-by-sequencing and variant calling for heterogeneous stock rats

Gao, J.; Gileta, A. F.; Bimschleger, H. V.; St. Pierre, C. L.; Gopalakrishnan, S.; Palmer, A. A.

10.1101/523043 — genetics — Posted on 2019-02-20

866 On simulating cold stunned turtle strandings on Cape Cod

Liu, X.; Manning, J.; Prescott, R.; Zou, H.; Faherty, M.

10.1101/418335 — ecology — Posted on 2019-02-20

867 Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 CNV Mediated Risk for Neuropsychiatric Disorders

Forsyth, J. K.; Nachun, D.; Gandal, M. J.; Geschwind, D. H.; Anderson, A. E.; Coppola, G.; Bearden, C. E.

10.1101/555490 — systems biology — Posted on 2019-02-20

868 A comprehensive data-driven model of cat primary visual cortex

Antolik, J.; Monier, C.; Fregnac, Y.; Davison, A. P.

10.1101/416156 — neuroscience — Posted on 2019-02-20

869 Defined neuronal populations drive fatal phenotype in Leigh Syndrome

Bolea, I.; Gella, A.; Sanz, E.; Prada-Dacasa, P.; Menardy, F.; Machuca-Marquez, P.; Bard, A. M.; Kalume, F.; Quintana, A.

10.1101/556019 — neuroscience — Posted on 2019-02-20

870 The autophagic membrane tether ATG2A transfers lipids between membranes

Maeda, S.; Otomo, C.; Otomo, T.

10.1101/555441 — cell biology — Posted on 2019-02-20

871 Phase resetting in human auditory cortex to visual speech

Megevand, P.; Mercier, M. R.; Groppe, D. M.; Zion Golumbic, E.; Mesgarani, N.; Beauchamp, M. S.; Schroeder, C. E.; Mehta, A. D.

10.1101/405597 — neuroscience — Posted on 2019-02-20

872 Two-photon frequency division multiplexing for functional in vivo imaging: a feasibility study.

Tsyboulski, D.; Orlova, N.; Ledochowitsch, P.; Saggau, P.

10.1101/405118 — neuroscience — Posted on 2019-02-20

873 Sex differences in fear regulation and reward seeking behaviors in a fear-safety-reward discrimination task

Greiner, E. M.; Norris, M. R.; Mueller, I.; Ng, K. H.; Sangha, S.

10.1101/390377 — neuroscience — Posted on 2019-02-20

874 The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

Zhu, S. J.; Hendry, J. A.; Almagro-Garcia, J.; Pearson, R. D.; Amato, R.; Miles, A.; Weiss, D. J.; Lucas, T. C. D.; Nguyen, M.; Gething, P. W.; Kwiatkowski, D.; McVean, G.; Pf3k Project,

10.1101/387266 — epidemiology — Posted on 2019-02-20

875 Metabolic Modulation Predicts Heart Failure Tests Performance

Contaifer, D.; Buckley, L. F.; Wohlford, G.; Kumar, N. G.; Morriss, J. M.; Ranasinghe, A. D.; Carbone, S.; Canada, J. M.; Trankle, C.; Abbate, A.; Van Tassell, B. W.; Wijesinghe, D.

10.1101/555417 — biochemistry — Posted on 2019-02-20

876 Sox6: A new modulator of renin expression during physiological conditions

Saleem, M.; Hodgkinson, C. P.; Contreras, E. W.; Xiao, L.; Gimenez-Bastida, J. A.; Foss, J.; Payne, A. J.; Mirotsou, M.; Gama, V.; Dzau, V. J.; Gomez, J. A.

10.1101/556118 — physiology — Posted on 2019-02-20

877 Human defensive freezing is associated with acute threat coping, long term hair cortisol levels and trait anxiety.

Hashemi, M. M.; Zhang, W.; Kaldewaij, R.; Koch, S.; Jonker, R.; Figner, B.; Klumpers, F.; Roelofs, K.

10.1101/554840 — physiology — Posted on 2019-02-20

878 TMS-EEG signatures of glutamatergic neurotransmission in human cortex

Koenig, F.; Belardinelli, P.; Liang, C.; Desideri, D.; Mueller-Dahlhaus, F.; Caldana Gordon, P.; Zipser, C.; Zrenner, C.; Ziemann, U.

10.1101/555920 — neuroscience — Posted on 2019-02-20

879 Conjugated linolenic fatty acids trigger ferroptosis in triple-negative breast cancer

Beatty, A.; Singh, T.; Tyurina, Y. Y.; Nicolas, E.; Maslar, K.; Zhou, Y.; Cai, K. Q.; Tan, Y.; Doll, S.; Conrad, M.; Bayır, H.; Kagan, V. E.; Rennefahrt, U.; Peterson, J. R.

10.1101/556084 — cancer biology — Posted on 2019-02-20

880 SIPA1L2 controls trafficking and signaling of TrkB-containing amphisomes at presynaptic terminals

Andres-Alonso, M.; Ammar, M. R.; Butnaru, I.; Gomes, G. M.; Sanhueza, G. A.; Raman, R.; Yuanxiang, P.; Borgmeyer, M.; Lopez-Rojas, J.; Raza, S. A.; Brice, N.; Hausrat, T. J.; Macharadze, T.; Diaz-Gonzalez, S.; Carlton, M.; Failla, A. V.; Stork, O.; Schweizer, M.; Gundelfinger, E. D.; Kneussel, M.; Spilker, C.; Karpova, A.; Kreutz, M. R.

10.1101/556266 — neuroscience — Posted on 2019-02-20

881 How prolonged expression of Hunchback, a temporal transcription factor, re-wires locomotor circuits

Heckscher, E.; Meng, J. L.; Marshall, Z. D.; Lobb-Rabe, M.

10.1101/556209 — developmental biology — Posted on 2019-02-20

882 Mouse model of the human serotonin transporter-linked polymorphic region

Piszczek, L.; Memoli, S.; Raggioli, A.; Viosca, J.; Rientjes, J.; Hublitz, P.; Czaban, W.; Wyrzykowska, A.; Gross, C.

10.1101/556092 — neuroscience — Posted on 2019-02-20

883 A Sequence Learning Model for Decision Making in the Brain

Zhang, Z.; Cheng, H.; Lin, Z.; Yang, T.

10.1101/555862 — neuroscience — Posted on 2019-02-20

884 Brain gene expression in a novel mouse model of postpartum mood disorder

Humby, T.; Davies, W.

10.1101/555870 — neuroscience — Posted on 2019-02-20

885 Automated analysis of small RNA datasets with RAPID

Karunanithi, S.; Simon, M.; Schulz, M. H.

10.1101/303750 — bioinformatics — Posted on 2019-02-20

886 Single-trial characterization of neural rhythms: potentials and challenges

Kosciessa, J. Q.; Grandy, T. H.; Garrett, D. D.; Werkle-Bergner, M.

10.1101/356089 — neuroscience — Posted on 2019-02-20

887 Systemic Lymphoid Architecture Response Assessment (SYLARAS): An approach to multi-organ, discovery-based immunophenotyping implicates a role for CD45R/B220+ CD8T cells in glioblastoma immunology

Baker, G. J.; Palaniappan, S. K.; Moore, J. K.; Davis, S. H.; Santagata, S.; Sorger, P. K.

10.1101/555854 — immunology — Posted on 2019-02-20

888 Deep behavioural phenotyping reveals divergent trajectories of ageing and quantifies health state in C. elegans

Martineau, C. N.; Baskaner, B.; Seinstra, R. I.; Schafer, W. R.; Brown, A. E.; Nollen, E. A.; Laurent, P.

10.1101/555847 — systems biology — Posted on 2019-02-20

889 Model-based integration of genomics and metabolomics reveals SNP functionality in Mycobacterium tuberculosis

Oeyas, O.; Borrel, S.; Trauner, A.; Zimmermann, M.; Feldmann, J.; Gagneux, S.; Stelling, J.; Sauer, U.; Zampieri, M.

10.1101/555763 — systems biology — Posted on 2019-02-20

890 Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice

Sit, B.; Zhang, T.; Fakoya, B.; Akter, A.; Biswas, R.; Ryan, E. T.; Waldor, M. K.

10.1101/554303 — microbiology — Posted on 2019-02-20

891 In Situ Electrochemical Studies of the Terrestrial Deep Subsurface Biosphere at the Sanford Underground Research Facility, South Dakota, USA

Jangir, Y.; Karbelkar, A. A.; Beedle, N. M.; Zinke, L. A.; Wanger, G.; Anderson, C. M.; Reese, B. K.; Amend, J. P.; El-Naggar, M. Y.

10.1101/555474 — microbiology — Posted on 2019-02-20

892 The influence of sex on the urogenital microbiome of rhesus monkeys

Hallmaier-Wacker, L. K.; Lueert, S.; Roos, C.; Knauf, S.

10.1101/555771 — microbiology — Posted on 2019-02-20

893 A Bayesian Approach for Estimating Branch-Specific Speciation and Extinction Rates

Hoehna, S.; Freyman, W. A.; Nolen, Z.; Huelsenbeck, J.; May, M. R.; Moore, B. R.

10.1101/555805 — evolutionary biology — Posted on 2019-02-20

894 Direct evidence of an increasing mutational load in humans

Aris-Brosou, S.

10.1101/307058 — evolutionary biology — Posted on 2019-02-20

895 MicroRNA-mediated control of developmental lymphangiogenesis

Jung, H. M.; Hu, C.; Fister, A. M.; Davis, A. E.; Castranova, D.; Pham, V. N.; Price, L. M.; Weinstein, B. M.

10.1101/555664 — developmental biology — Posted on 2019-02-20

896 Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Ehlen, A.; Martin, C.; Miron, S.; Julien, M.; Theillet, F. X.; Boucherit, V.; Ropars, V.; Duchambon, P.; El Marjou, A.; Zinn Justin, S.; Carreira, A.

10.1101/265934 — cell biology — Posted on 2019-02-20

897 csuWGCNA: a combination of signed and unsigned WGCNA to capture negative correlations

Dai, R.; Xia, Y.; Liu, C.; Chen, C.

10.1101/288225 — bioinformatics — Posted on 2019-02-20

898 Influence of Organic Matrix and Cations on Bio-Methane Yield with Anthracite Methanogenic Consortium

Xiao, D.; Wang, E.; Zhang, Y.

10.1101/555532 — bioengineering — Posted on 2019-02-20

899 A novel human enteroid-anaerobe co-culture system to study microbial-host interaction under physiological hypoxia

Fofanova, T. Y.; Stewart, C.; Auchtung, J. M.; Wilson, R. L.; Britton, R. A.; Grande-Allen, K. J.; Estes, M. K.; Petrosino, J. F.

10.1101/555755 — bioengineering — Posted on 2019-02-20

900 Reward prediction error modulates saccade vigor

Sedaghat-Nejad, E.; Herzfeld, D. J.; Shadmehr, R.

10.1101/555573 — neuroscience — Posted on 2019-02-20

901 The relationship between neural variability and neural oscillations

Daniel, E.; Dinstein, I.; Arazi, A.; Donner, T. H.; Meindertsma, T.

10.1101/555649 — neuroscience — Posted on 2019-02-20

902 Automatic and feature-specific (anticipatory) prediction-related neural activity in the human auditory system

Demarchi, G.; Sanchez, G.; Weisz, N.

10.1101/266841 — neuroscience — Posted on 2019-02-20

903 Mammalian orthoreovirus infection is enhanced in cells pre-treated with sodium arsenite

Lutz, M. M.; Worth, M. P.; Hinchman, M. M.; Parker, J. S. L.; Ledgerwood, E. D.

10.1101/555367 — microbiology — Posted on 2019-02-20

904 A global synthesis reveals biodiversity-mediated benefits for crop production

Dainese, M.; Martin, E. A.; Aizen, M.; Albrecht, M.; Bartomeus, I.; Bommarco, R.; Carvalheiro, L. G.; Chaplin-Kramer, R.; Gagic, V.; Garibaldi, L. A.; Ghazoul, J.; Grab, H.; Jonsson, M.; Karp, D. S.; Kennedy, C. M.; Kleijn, D.; Kremen, C.; Landis, D. A.; Letourneau, D. K.; Marini, L.; Poveda, K.; Rader, R.; Smith, H. G.; Tscharntke, T.; Andersson, G. K. S.; Badenhausser, I.; Baensch, S.; Bezerra, A. D. M.; Bianchi, F. J. J. A.; Boreux, V.; Bretagnolle, V.; Caballero-Lopez, B.; Cavigliasso, P.; Cetkovic, A.; Chacoff, N. P.; Classen, A.; Cusser, S.; Silva e Silva, F. D. d.; de Groot, G. A.; Dude

10.1101/554170 — ecology — Posted on 2019-02-20

905 TuBA: Tunable Biclustering Algorithm Reveals Clinically Relevant Tumor Transcriptional Profiles in Breast Cancer

Singh, A.; Bhanot, G.; Khiabanian, H.

10.1101/245712 — systems biology — Posted on 2019-02-20

906 An evolutionarily conserved mechanism for production of secondary meristems in land plants

Yasui, Y.; Tsukamoto, S.; Sugaya, T.; Nishihama, R.; Wang, Q.; Yamato, K. T.; Fukaki, H.; Mimura, T.; Kubo, H.; Theres, K.; Kohchi, T.; Ishizaki, K.

10.1101/555607 — plant biology — Posted on 2019-02-20

907 Pathological tau spreads through communicating brain regions in human Alzheimer's disease

Vogel, J.; Iturria-Medina, Y.; Strandberg, O. T.; Smith, R.; Evans, A. C.; Hansson, O.; for the Alzheimer's Disease Neuroimaging Initiative, ; the Swedish BioFINDER Study,

10.1101/555821 — neuroscience — Posted on 2019-02-20

908 Responses of bats to landscape transformation in an Andean agricultural landscape

Velez-Orozco, M.; Romero, L. M.; Castano, J.; Carranza-Quiceno, J. A. A.; Perez-Torres, J.; Torres, D. A.

10.1101/555516 — ecology — Posted on 2019-02-20

909 Classical conditioning drives learned reward prediction signals in climbing fibers across the lateral cerebellum

Heffley, W.; Hull, C.

10.1101/555508 — neuroscience — Posted on 2019-02-20

910 Nucleic Acid Cleavage with a Hyperthermophilic Cas9 from an Unculturable Ignavibacterium

Schmidt, S. T.; Yu, F. B.; Blainey, P. C.; May, A. P.; Quake, S. R.

10.1101/555169 — genomics — Posted on 2019-02-20

911 Pancreas patch-seq links physiologic dysfunction in diabetes to single-cell transcriptomic phenotypes

Camunas-Soler, J.; Dai, X.; Hang, Y.; Bautista, A.; Lyon, J.; Suzuki, K.; Kim, S. K.; Quake, S. R.; MacDonald, P. E.

10.1101/555110 — genomics — Posted on 2019-02-20

912 Evaluation of the psychometric properties of the HIV Disability Questionnaire among adults living with HIV in the United Kingdom

Brown, D. A.; Simmons, B.; Boffito, M.; Aubry, R.; Nwokolo, N.; Harding, R.; O'Brien, K. K.

10.1101/556183 — epidemiology — Posted on 2019-02-20

913 Gene regulatory network of human GM-CSF secreting T helper cells

Elias, S.; Schmidt, A.; Gomez-Cabrero, D.; Tegner, J.

10.1101/555433 — bioinformatics — Posted on 2019-02-20

914 Targeted mutagenesis of the SUMO protease, Overly Tolerant to Salt1 in rice through CRISPR/Cas9-mediated genome editing reveals a major role of this SUMO protease in salt tolerance.

Sadanandom, A.; Srivastava, A. K.; Zhang, C.

10.1101/555706 — plant biology — Posted on 2019-02-20

915 Newly Discovered migratory corridor and foraging ground for Atlantic green turtles, Chelonia mydas, nesting on Bioko Island, Equatorial Guinea

Mettler, E.; Clyde-Brockway, C. E.; Paladino, F. V.; Honarvar, S.

10.1101/556191 — zoology — Posted on 2019-02-20

916 Molecular signaling involved in immune system activation against root-knot nematodes by bio-control agents in tomato plants

Molinari, S.; Leonetti, P.

10.1101/556175 — plant biology — Posted on 2019-02-20

917 A single-cell reference map for human blood and tissue T cell activation reveals functional states in health and disease

Szabo, P. A.; Levitin, H. M.; Miron, M.; Snyder, M. E.; Senda, T.; Yuan, J.; Cheng, Y. L.; Bush, E. C.; Dogra, P.; Thapa, P.; Farber, D. L.; Sims, P. A.

10.1101/555557 — immunology — Posted on 2019-02-20

918 An insect serotonin receptor mediates cellular immune responses and its inhibition by phenylethylamide derivatives from bacterial secondary metabolites

Kim, Y.; Hasan, A.; Yeom, H.-S.; Ryu, J.; Bode, H.

10.1101/556159 — immunology — Posted on 2019-02-20

919 Cognate epitope recognition by bovine CD4 and CD8 T cells is essential for primary expansion of antigen-specific cytotoxic T-cells following ex vivo stimulation with a candidate Mycobacterium avium subsp. paratuberculosis peptide vaccine.

Davis, W. C.; Abdellrazeq, G. M.; Fry, L. M.; Elnaggar, M. M.; Bannantine, J. P.; Schneider, D. A.; Chamberlin, W. M.; Mahmoud, A. H. A.; Park, K.-T.; Hulubei, V.

10.1101/555672 — immunology — Posted on 2019-02-20

920 IL-27 receptor signaling regulated stress myelopoiesis drives Abdominal Aortic Aneurysm development

Peshkova, I.; Aghayev, T.; Fatkhullina, A.; Makhov, P.; Eguchi, S.; Tan, Y. F.; Kossenkov, A.; Sykes, S.; Koltsova, E.

10.1101/555581 — immunology — Posted on 2019-02-20

921 Structural features underlying the activity of benzimidazole derivatives that target phosphopeptide recognition by the tandem BRCT domain of the BRCA1 protein

Kurdekar, V.; Giridharan, S.; Jasti, S.; Nijaguna, M. B.; Periyasamy, J.; Boggaram, S.; Bharatham, K.; Potluri, V.; Shivange, A. V.; Sadasivam, G.; Padigaru, M.; Venkitaraman, A. R.

10.1101/555623 — cancer biology — Posted on 2019-02-20

922 Recombination and mutational robustness in neutral fitness landscapes

Klug, A.; Park, S.-C.; Krug, J.

10.1101/556134 — evolutionary biology — Posted on 2019-02-20

923 Recombinant production and purification of the human protein Tau

Ferrari, L.; Rudiger, S. G. D.

10.1101/545566 — biochemistry — Posted on 2019-02-20

924 Calculating the maximum capacity of intracellular transport vesicles

Martins Ratamero, E.; Royle, S. J.

10.1101/555813 — cell biology — Posted on 2019-02-20

925 3D computational models explain muscle activation patterns and energetic functions of internal structures in fish swimming

Ming, T.; Jin, B.; Song, J.; Luo, H.; Du, R.; Ding, Y.

10.1101/556126 — biophysics — Posted on 2019-02-20

926 Sex differences in fear regulation and reward seeking behaviors in a fear-safety-reward discrimination task

Greiner, E. M.; Norris, M. R.; Mueller, I.; Ng, K. H.; Sangha, S.

10.1101/390377 — neuroscience — Posted on 2019-02-20

927 Metabolic Reprogramming: Short-term Western Diet Exposure Induces Sustained Changes in Plasma Metabolites

Misra, B. B.; Upadhayay, R. P.; Mattern, V.; Parks, J. S.; Cox, L. A.; Comuzzie, A. G.; Olivier, M.

10.1101/554980 — systems biology — Posted on 2019-02-20

928 A late Permian ichthyofauna from the Zechstein Basin, Lithuania-Latvia Region

Dankina-Beyer, D.; Spiridonov, A.; Stinkulis, G.; Manzanares, E.; Radzevicius, S.

10.1101/554998 — paleontology — Posted on 2019-02-20

929 Raman Spectroscopic Study of the Influence of Oxytocin and Uvariodendron anisatum Verdeck (Annonaceae) Freeze-dried Extracts on Diet Induced Obesity in Sprague Dawley Rats

Birech, Z.; Sehmi, P. K.; Mwangi, P. W.; Nyaga, N. M.

10.1101/554956 — biophysics — Posted on 2019-02-20

930 Localization microscopy at doubled precision with patterned illumination

Cnossen, J.; Hinsdale, T.; Thorsen, R.; Schueder, F.; Jungmann, R.; Smith, C. S.; Rieger, B.; Stallinga, S.

10.1101/554337 — molecular biology — Posted on 2019-02-20

931 SURF1 mutations causative of Leigh syndrome impair human neurogenesis

Inak, G.; Rybak-Wolf, A.; Lisowski, P.; Juettner, R.; Zink, A.; Mlody, B.; Glazar, P.; Secker, C.; Ciptasari, U. H.; Stenzel, W.; Hahn, T.; Diecke, S.; Priller, J.; Gotthardt, M.; Kuehn, R.; Wanker, E. E.; Rajewsky, N.; Schuelke, M.; Prigione, A.

10.1101/551390 — neuroscience — Posted on 2019-02-20

932 Twinkle is not the mitochondrial DNA replicative helicase in C. elegans, but may have alternate mitochondrial functions

Henderson, H. R.; Liliya, E.; Suomalainen, A.; Dillin, A.

10.1101/497305 — molecular biology — Posted on 2019-02-20

933 A CyclinB2-Cas9 fusion promotes the homology-directed repair of double-strand breaks

Vicente, M. M.; Mendes, A.; Cruz, M.; Vicente, J. R.; Barreto, V. M.

10.1101/555144 — molecular biology — Posted on 2019-02-20

934 Transcriptome stability profiling identifies novel and functional MIRNA targets in melanoma cells

Joshi, P.; Seki, T.; Bergano, A.; Marchica, J.; Kitamura, S.; Perera, R. J.

10.1101/555540 — cancer biology — Posted on 2019-02-20

935 The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor

LeVine, M. V.; Terry, D. S.; Khelashvili, G.; Siegel, Z. S.; Quick, M.; Javitch, J. A.; Blanchard, S. C.; Weinstein, H.

10.1101/555565 — biophysics — Posted on 2019-02-20

936 Kinpute: Using identity by descent to improve genotype imputation

Abney, M.; El Sherbiny, A.

10.1101/399147 — genetics — Posted on 2019-02-19

937 Significant temporal shifts on clonal and plasmid backgrounds of Enterobacteriaceae producing acquired AmpC in Portuguese clinical settings

Ribeiro, T. G.; Novais, A.; Rodrigues, C.; Nascimento, R.; Freitas, F.; Machado, E.; Peixe, L.

10.1101/553164 — epidemiology — Posted on 2019-02-19

938 Deep Genomic Signature for early metastasis prediction in prostate cancer

Sharifi-Noghabi, H.; Liu, Y.; Erho, N.; Shrestha, R.; Alshalalfa, M.; Davicioni, E.; Collins, C. C.; Ester, M.

10.1101/276055 — bioinformatics — Posted on 2019-02-19

939 Computational tool to study perturbations in muscle regulation and its application to heart disease

Barrick, S. K.; Clippinger, S. R.; Greenberg, L.; Greenberg, M. J.

10.1101/548404 — biophysics — Posted on 2019-02-19

940 Omnivory does not preclude strong trophic cascades

Fahimipour, A. K.; Levin, D. A.; Anderson, K. E.

10.1101/441535 — ecology — Posted on 2019-02-19

941 Sox17 expression in endocardium precursor cells regulates heart development in mice

Saba, R.; Kitajima, K.; Rainbow, L.; Engert, S.; Uemura, M.; Ishida, H.; Kokkinopoulos, I.; Shintani, Y.; Miyagawa, S.; Kanai, Y.; Azuma-Kanai, M.; Koopman, P.; Meno, C.; Kenny, J.; Lickert, H.; Saga, Y.; Suzuki, K.; Sawa, Y.; Yashiro, K.

10.1101/548289 — developmental biology — Posted on 2019-02-19

942 Metabolic landscape of the tumor microenvironment

Xiao, Z.; Dai, Z.; Locasale, J. W.

10.1101/527952 — cancer biology — Posted on 2019-02-19

943 Multi-omic analysis supports a developmental hierarchy of molecular subtypes in high-grade serous ovarian carcinoma

Geistlinger, L.; Oh, S.; Ramos, M.; Schiffer, L.; Winterhoff, B.; Morgan, M.; Parmigiani, G.; Birrer, M.; Qin, L.-X.; Riester, M.; Starr, T.; Waldron, L.

10.1101/554394 — cancer biology — Posted on 2019-02-19

944 Visualizing Conformational Transitions of the Lipid II Flippase MurJ

Kuk, A. C. Y.; Hao, A.; Guan, Z.; Lee, S.-Y.

10.1101/552745 — biochemistry — Posted on 2019-02-19

945 Identification of transgene-free CRISPR edited plants of rice and tomato by monitoring DsRED fluorescence in dry seeds

Aliaga-Franco, N.; Zhang, C.; Presa, S.; Srivastava, A. K.; Granell, A.; Alabadi, D.; Sadanandom, A.; Blazquez, M. A.; Minguet, E. G.

10.1101/533034 — plant biology — Posted on 2019-02-19

946 Resident memory CD8 T cells persist for years in human small intestine

Bartolome Casado, R.; Landsverk, O. J. B.; Chauhan, S. K.; Richter, L.; Phung, D.; Greiff, V.; Risnes, L. F.; Yao, Y.; Neumann, R. S.; Yaqub, S.; Oyen, O.; Horneland, R.; Aandahl, E. M.; Paulsen, V.; Sollid, L. M.; Qiao, S.-W.; Baekkevold, E. S.; Jahnsen, F. L.

10.1101/553792 — immunology — Posted on 2019-02-19

947 Virus-like vesicles expressing multiple antigens for immunotherapy of chronic hepatitis B

Yarovinsky, T. O.; Mason, S. W.; Menon, M.; Krady, M. M.; Haslip, M.; Madina, B. R.; Ma, X.; Moshkani, S.; Chiale, C.; Chattopadhyay Pal, A.; Almassian, B.; Rose, J. K.; Robek, M. D.; Nakaar, V.

10.1101/491985 — immunology — Posted on 2019-02-19

948 The oncoprotein DEK affects the outcome of PARP1/2 inhibition during replication stress

Ferrando-May, E.; Ganz, M.; Vogel, C.; Czada, C.; Jörke, V.; Kleiner, R.; Pierzynska-Mach, A.; Zanacchi, F. C.; Diaspro, A.; Kappes, F.; Bürkle, A.

10.1101/555003 — cancer biology — Posted on 2019-02-19

949 Accelerating Dissociative Events in Molecular Dynamics Simulations by Selective Potential Scaling

Deb, I.; Frank, A. T.

10.1101/547307 — biophysics — Posted on 2019-02-19

950 Computational tool to study perturbations in muscle regulation and its application to heart disease

Barrick, S. K.; Clippinger, S. R.; Greenberg, L.; Greenberg, M. J.

10.1101/548404 — biophysics — Posted on 2019-02-19

951 Adapted dandelions increase seed dispersal potential when they are attacked by root herbivores

Bont, Z.; Pfander, M.; Robert, C. A. M.; Huber, M.; Poelman, E. H.; Raaijmakers, C. E.; Erb, M.

10.1101/551630 — ecology — Posted on 2019-02-19

952 Marked compositional changes in harvestmen assemblages in Amazonian forest islands induced by a mega dam

Tourinho, A. L.; Benchimol, M.; Porto, W.; Peres, C.; Storck Tonon, D.

10.1101/542969 — ecology — Posted on 2019-02-19

953 Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators

Godwin, W. C.; Hoffmann, G. F.; Gray, T. J.; Hughes, R. M.

10.1101/551788 — biochemistry — Posted on 2019-02-19

954 The urge to blink in Tourette syndrome

Botteron, H. E.; Richards, C. A.; Nishino, T.; Ueda, K.; Acevedo, H. K.; Koller, J. M.; Black, K. J.

10.1101/477372 — neuroscience — Posted on 2019-02-19

955 An Interscholastic Network to Generate LexA Enhancer Trap Lines in Drosophila

Kockel, L.; Griffin, C.; Ahmed, Y.; Fidelak, L.; Rajan, A.; Gould, E. P.; Haigney, M.; Ralston, B.; Tercek, R. J.; Galligani, L.; Rao, S.; Huq, L.; Bhargava, H. K.; Dooner, A. C.; Lemmerman, E. G.; Malusa, R. F.; Nguyen, T. H.; Chung, J. S.; Gregory, S. M.; Kuwana, K. M.; Regenold, J. T.; Wei, A.; Ashton, J.; Dickinson, P.; Martel, K.; Cai, C.; Chen, C.; Price, S.; Qiao, J.; Shepley, D.; Zhang, J.; Chalasani, M.; Nguyen, K.; Aalto, A.; Kim, B.; Tazawa-Goodchild, E.; Sherwood, A.; Rahman, A.; Wu, S. Y. C.; Lotzkar, J.; Michaels, S.; Aristotle, H.; Clark, A.; Gasper, G.; Xiang, E.; Schlor, F. L.

10.1101/552513 — genetics — Posted on 2019-02-19

956 Species dispersal mediates opposing influences of a branching network on genetic variation in a metapopulation

Chiu, M.-C.; Li, B.; Nukazawa, K.; Carvajal, T.; Watanabe, K.

10.1101/550194 — ecology — Posted on 2019-02-19

957 Gaussian Process Based Heteroscedastic Noise Modeling for Tumor Mutation Burden Prediction from Whole Slide Images

Park, S.; Xu, H.; Hwang, T. H.

10.1101/554261 — bioinformatics — Posted on 2019-02-19

958 Intravital optoacoustic ultrasound bio-microscopy reveals radiation-inhibited skull angiogenesis

Estrada, H.; Rebling, J.; Sievert, W.; Hladik, D.; Hofmann, U.; Gottschalk, S.; Tapio, S.; Multhoff, G.; Razansky, D.

10.1101/500017 — bioengineering — Posted on 2019-02-19

959 Frontal and parietal alpha oscillations reflect attentional modulation of cross-modal matching

Misselhorn, J.; Friese, U.; Engel, A. K.

10.1101/477034 — neuroscience — Posted on 2019-02-19

960 Optimal use of statistical methods to validate reference gene stability in longitudinal studies

Sundaram, V. K.; Sampathkumar, N. K.; Massaad, C.; Grenier, J.

10.1101/545749 — molecular biology — Posted on 2019-02-19

961 Deconvolution of bulk blood eQTL effects into immune cell subpopulations

Aguirre-Gamboa, R.; de Klein, N.; di Tommaso, J.; Claringbould, A.; Vosa, U.; Zorro, M.; Chu, X.; Bakker, O. O.; Borek, Z.; Ricano-Ponce, I.; Deelen, P.; J. Xu, C.; Swertz, M.; Jonkers, I.; Withoff, S.; Joosten, I.; Sanna, S.; Kumar, V.; Koenen, H. J. P. M.; Joosten, L. A. B.; Netea, M. G.; Wijmenga, C.; BIOS Consortium, ; Franke, L.; Li, Y.

10.1101/548669 — genomics — Posted on 2019-02-19

962 Phylogenetic systematics and evolution of the spider infraorder Mygalomorphae using genomic scale data

Opatova, V.; Hamilton, C. A.; Hedin, M.; Montes de Oca, L.; Kral, J.; Bond, J. E.

10.1101/531756 — evolutionary biology — Posted on 2019-02-19

963 The neuronal ceroid lipofuscinosis protein Cln7 regulates neural development from the post-synaptic cell

Connolly, K. B.; O'Hare, M. B.; Mohammed, A.; Aitchison, K. C.; Anthoney, N. C.; Roberts, A. L.; Taylor, M. J.; Stewart, B. A.; Tuxworth, R. I.; Tear, G.

10.1101/278895 — developmental biology — Posted on 2019-02-19

964 Multiple-Strain Infections of Human Cytomegalovirus with High Genomic Diversity are Common In Breast Milk from HIV-Positive Women in Zambia

Suarez, N.; Musonda, K. G.; Escriva, E.; Njenga, M.; Agbueze, A.; Camiolo, S.; Davison, A. J.; Gompels, U. A.

10.1101/493742 — genomics — Posted on 2019-02-19

965 Predicting gene expression in the human malaria parasite Plasmodium falciparum

Read, D. F.; Cook, K.; Lu, Y. Y.; Le Roch, K.; Noble, W.

10.1101/431049 — genomics — Posted on 2019-02-19

966 The landscape of pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases

Jordan, D. M.; Verbanck, M.; Do, R.

10.1101/311332 — genetics — Posted on 2019-02-19

967 The Bellerophon pipeline, improving de novo transcriptomes and removing chimeras

Kerkvliet, J.; de Fouchier, A.; van Wijk, M.; Groot, A. T.

10.1101/495754 — bioinformatics — Posted on 2019-02-19

968 Mathematical modeling suggests that benefits of short or long antibiotic treatment depend on details of infection

Pauperio, F. F. S.; Ganusov, V. V.; Gjini, E.

10.1101/555334 — systems biology — Posted on 2019-02-19

969 Case-only analysis of gene-environment interactions using polygenic risk scores

Meisner, A.; Kundu, P.; Chatterjee, N.

10.1101/555300 — genetics — Posted on 2019-02-19

970 Metagenomic dynamics in Olea europaea after root damage and Verticillium dahliae infection

Marti, J. M.; Arias, L. F.; Diaz-Villanueva, W.; Arnau, V.; Rodriguez-Franco, A.; P. Garay, C.

10.1101/555185 — systems biology — Posted on 2019-02-19

971 Genome-wide estimates of heritability and genetic correlations in Essential Tremor

Diez-Fairen, M.; Bandres-Ciga, S.; Houle, G.; Nalls, M. A.; Girard, S. L.; Dion, P. A.; Blauwendraat, C.; Singleton, A.; Rouleau, G. A.; Pastor, P.

10.1101/555235 — genetics — Posted on 2019-02-19

972 Viruses rule over adaptation in conserved human proteins

Castellano, D.; Uricchio, L. H.; Munch, K.; Enard, D.

10.1101/555060 — evolutionary biology — Posted on 2019-02-19

973 Computational tool to study perturbations in muscle regulation and its application to heart disease

Barrick, S. K.; Clippinger, S. R.; Greenberg, L.; Greenberg, M. J.

10.1101/548404 — biophysics — Posted on 2019-02-19

974 An oligarchy of NO-producing interneurons controls basal and evoked blood flow in the cortex

Echagarruga, C.; Gheres, K.; Drew, P. J.

10.1101/555151 — neuroscience — Posted on 2019-02-19

975 Orthogonal Representations of Object Shape and Category in Deep Convolutional Neural Networks and Human Visual Cortex

Zeman, A.; Ritchie, J. B.; Bracci, S.; Op de Beeck, H.

10.1101/555193 — neuroscience — Posted on 2019-02-19

976 Notch signalling mediates secondary senescence

Teo, Y. V.; Rattanavirotkul, N.; Salzano, A.; Quintanilla, A.; Tarrats, N.; Kiourtis, C.; Mueller, M.; Green, A. R.; Adams, P. D.; Acosta, J.-C.; Bird, T. G.; Kirschner, K.; Neretti, N.; Chandra, T.

10.1101/554741 — genomics — Posted on 2019-02-19

977 The Effects of Mutations are Modified by Genetic Background in Mice

Rau, C. D.; Gonzales, N. M.; Park, D.; Palmer, A. A.; Lusis, A. J.; Zaitlen, N.

10.1101/555383 — genomics — Posted on 2019-02-19

978 Complete genome sequence of Bacillus velezensis JT3-1, a microbial germicide isolated from yak feces

Li, Y.; Li, X.; Jia, D.; Liu, J.; Wang, J.; Liu, A.; Guan, G.; Liu, Z.; Liu, G.; Luo, J.; Yin, H.

10.1101/555219 — genomics — Posted on 2019-02-19

979 Inbreeding depression causes reduced fecundity in Golden Retrievers

Chu, E. T.-J.; Simpson, M.; Diehl, K.; Page, R.; Sams, A. J.; Boyko, A.

10.1101/554592 — genomics — Posted on 2019-02-19

980 Exact p-values for large-scale single step genome-wide association, with an application for birth weight in American Angus

Aguilar, I.; Legarra, A.; Cardoso, F.; Masuda, Y.; Lourenco, D.; Misztal, I.

10.1101/555243 — genomics — Posted on 2019-02-19

981 The relative importance of biotic and abiotic determinants of temporal occupancy for avian species in North America

Snell Taylor, S.; Umbanhowar, J.; Hurlbert, A.

10.1101/555227 — ecology — Posted on 2019-02-19

982 Microstructure of Ingestive Behaviors in Mus Musculus

Onnis, G.; Layco-Bader, E.; Tecott, L.

10.1101/529198 — animal behavior and cognition — Posted on 2019-02-19

983 Epigenetic landscape and AAV targeting of human neocortical cell classes

Mich, J. K.; Hess, E. E.; Graybuck, L. T.; Somasundaram, S.; Miller, J. A.; Ding, Y.; Shapovalova, N. V.; Fong, O.; Yao, S.; Mortrud, M.; Chong, P.; Bertagnolli, D.; Goldy, J.; Casper, T.; Kroll, M.; Hodge, R. D.; Bakken, T. E.; Yao, Z.; Dee, N.; Cetin, A.; Smith, K. A.; Gwinn, R. P.; Cobbs, C.; Ko, A. L.; Ojemann, J. G.; Keene, C. D.; Silbergeld, D. L.; Gradinaru, V.; Sunkin, S. M.; Zeng, H.; Lein, E. S.; Tasic, B.; Ting, J. T.; Levi, B. P.

10.1101/555318 — neuroscience — Posted on 2019-02-19

984 Distinct subdivisions of human medial parietal cortex are recruited differentially for memory recall of places and people

Silson, E. H.; Steel, A.; Kidder, A.; Gilmore, A. W.; Baker, C. I.

10.1101/554915 — neuroscience — Posted on 2019-02-19

985 Single molecule real time (SMRT) full length RNA-sequencing reveals novel and distinct mRNA isoforms in human bone marrow cell subpopulations

Deslattes Mays, A.; Schmidt, M. O.; Graham, G.; Tseng, E.; Baybayan, P.; Sebra, R.; Miloslav, S.; Mazarati, J.-B.; Riegel, A. T.; Wellstein, A.

10.1101/555326 — molecular biology — Posted on 2019-02-19

986 Discovery of several thousand highly diverse circular DNA viruses

Tisza, M. J.; Pastrana, D. V.; Welch, N. L.; Stewart, B.; Peretti, A.; Starrett, G. J.; Pang, Y.-Y. S.; Varsani, A.; Krishnamurthy, S. R.; Pesavento, P. A.; McDermott, D. H.; Murphy, P. M.; Whited, J. L.; Miller, B.; Brenchley, J. M.; Rosshart, S. P.; Rehermann, B.; Doorbar, J.; Ta'ala, B. A.; Pletnikova, O.; Troncoso, J.; Resnick, S. M.; Segall, A. M.; Buck, C. B.

10.1101/555375 — microbiology — Posted on 2019-02-19

987 The Nonlinear Relations that Predict Influenza Viral Dynamics, CD8+ T cell-Mediated Clearance, Lung Pathology, and Disease Severity

Myers, M. A.; Smith, A. P.; Lane, L. C.; Moquin, D. J.; Michael, R.; Vogel, P.; Woolard, S.; Smith, A. M.

10.1101/555276 — microbiology — Posted on 2019-02-19

988 synder: inferring genomic orthologs from synteny maps

Arendsee, Z.; Wilkey, A.; Singh, U.; Li, J.; Hur, M.; Wurtele, E.

10.1101/554501 — bioinformatics — Posted on 2019-02-19

989 Immune-informed mucin hydrogels evade fibrotic foreign body response in vivo

Yan, H.; Seignez, C.; Hjorth, M.; Winkeljann, B.; Lieleg, O.; Phillipson, M.; Crouzier, T.

10.1101/554865 — bioengineering — Posted on 2019-02-19

990 Cross-Species Alignment of Single Cell States with Biological Process Activity

Ding, H.; Blair, A.; Stuart, J.

10.1101/555268 — systems biology — Posted on 2019-02-19

991 Elevated CO2 induces age-dependent restoration of growth and metabolism in gibberellin-deficient plants

Gasparini, K.; Costa, L. C.; Brito, F. A. L.; Pimenta, T. M.; Cardoso, F. B.; Araujo, W. L.; Zsögön, A.; Ribeiro, D. M.

10.1101/555292 — plant biology — Posted on 2019-02-19

992 Prolonged Ocular Exposure Leads to the Formation of Retinal Lesions in Mice

Bell, B. A.; Bonilha, V.; Hagstrom, S.; Anand-Apte, B.; Hollyfield, J. G.; Samuels, I.

10.1101/550236 — pathology — Posted on 2019-02-19

993 Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

Bertero, A.; Fields, P. A.; Smith, A. S.; Leonard, A.; Beussman, K.; Sniadecki, N. J.; Kim, D.-H.; Tse, H.-F.; Pabon, L.; Shendure, J.; Noble, W. S.; Murry, C. E.

10.1101/555250 — genomics — Posted on 2019-02-19

994 Detecting natural hybridization among Indian major carps through advance morphometric approach

Dwivedi, A. K.

10.1101/553941 — zoology — Posted on 2019-02-19

995 The Process Pathway Model of bacterial growth

Biro, D.; Pechuan, X.; Bergman, A.; Lambros, M.

10.1101/553982 — systems biology — Posted on 2019-02-19

996 In Vitro Activity of Eravacycline in Combination with Colistin Against Carbapenem-Resistant A. baumannii Isolates

Ozger, H. S.; Cuhadar, T.; Suzuk Yildiz, S.; Demirbas Gulmez, Z.; Dizbay, M.; Guzel Tunccan, O.; Kalkanci, A.; Simsek, H.; Unaldi, O.

10.1101/552547 — microbiology — Posted on 2019-02-19

997 Corneal Biomechanical Alterations in Patients with Chronic Ocular Graft Versus-host Disease

Giannaccare, G.; Pellegrini, M.; Taroni, L.; Bernabei, F.; Senni, C.; Grendele, A.; Scorcia, V.; Campos, E.

10.1101/553867 — pathology — Posted on 2019-02-19

998 Association of Functional Variants and Protein-to-Protein Physical Interactions of Human MutY homolog linked with Familial Adenomatous Polyposis and colorectal cancer Syndrome

Abduljaleel, Z.; Vazquez, J. R.; Gorodkin, J.

10.1101/552943 — genetics — Posted on 2019-02-19

999 Cryptococcus neoformans secretes small molecules that inhibit IL-1β inflammasome-dependent secretion

Bürgel, P. H.; Marina, C. L.; Saavedra, P. H. V.; Albuquerque, P.; Holanda, P. H.; Castro, R. d. A.; Heyman, H.; Coelho, C.; Cordero, R. J. B.; Casadevall, A.; Nosanchuk, J.; Nakayasu, E.; May, R. C.; Tavares, A. H.; Bocca, A.

10.1101/554048 — immunology — Posted on 2019-02-19

1000 Nonlinear diversification rates of linguistic phylogenies over the Holocene

Hamilton, M. J.; Walker, R. S.

10.1101/553966 — evolutionary biology — Posted on 2019-02-19

1001 Diversified Diet Feeding Practice is Low Compared to the WHO Recommendation in the Dabat Demographic and Health Surveillance System Site: Finding from the Baseline Survey of Nutrition Project, 2016

Abebe, Z.; Tariku, A.; Bikes, G. A.; Wassie, M. M.; Abdella, K.; Awoke, T.; Gebeye, E.; Gete, A. A.; Yesuf, M. E.; Kebede, Y.; Alemu, K.; Addis, A.; Muhammad, E. A.; Fentahun, K.; Abebe, S. M.; Tamir, M.; Fentie, M.; Kebede, A.; Belew, A. K.

10.1101/553875 — epidemiology — Posted on 2019-02-19

1002 Effects of the secondhand smoking exposure in the early stages of the bone development

Alves, C. F.; Carvalho, C. A. F.; Iemma, A. F.; Neto, F. H.; Caria, P. H. F.

10.1101/553834 — developmental biology — Posted on 2019-02-19

1003 OsLUGL involved in floral development through regulating auxin level and OsARFs expression in rice (Oryza sative L.)

Yang, C.; Li, D.; Zhu, X.; Wei, Z.; Feng, Z.; Zhang, L.; He, J.; Liu, X.; Mou, C.; Jiang, L.; Wan, J.

10.1101/552612 — genetics — Posted on 2019-02-19

1004 Possible co-option of a VEGF-driven tubulogenesis program for biomineralization in echinoderms

Ben-Tabou de-Leon, S.; Gildor, T.; Sher, N.; Roopin, M.; Morgulis, M.; Malik, A.; Dines, M.; Lalzar, M.; Khalaily, L.

10.1101/554683 — evolutionary biology — Posted on 2019-02-19

1005 Classification of visual cortex plasticity phenotypes following treatment for amblyopia

Balsor, J.; Jones, D. G.; Murphy, K. M.

10.1101/554576 — neuroscience — Posted on 2019-02-19

1006 Evaluating Invasive EEG Implantations in Medically Refractory Epilepsy with Functional Scalp EEG Recordings and Structural Imaging Data

Li, A.; Palepu, A.; Fitzgerald, Z.; Hu, K.; Costacurta, J.; Bulacio, J.; Martinez-Gonzalez, J.; Sarma, S.

10.1101/554667 — neuroscience — Posted on 2019-02-19

1007 MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

Wu, Z.; Tantray, I.; Lim, J.; Chen, S.; Li, Y.; Davis, Z.; Citron, C.; Dong, J.; Gispert, S.; Auburger, G.; Brandman, O.; Bi, X.; Snyder, M.; Lu, B.

10.1101/554634 — cell biology — Posted on 2019-02-19

1008 Multi-omic analysis supports a developmental hierarchy of molecular subtypes in high-grade serous ovarian carcinoma

Geistlinger, L.; Oh, S.; Ramos, M.; Schiffer, L.; Winterhoff, B.; Morgan, M.; Parmigiani, G.; Birrer, M.; Qin, L.-X.; Riester, M.; Starr, T.; Waldron, L.

10.1101/554394 — cancer biology — Posted on 2019-02-19

1009 Spatial metabolomics of in situ, host-microbe interactions

Geier, B. K.; Sogin, E.; Michellod, D.; Janda, M.; Kompauer, M.; Spengler, B.; Dubilier, N.; Liebeke, M.

10.1101/555045 — microbiology — Posted on 2019-02-19

1010 Transcriptional Error Rates Vary by Gene Expression Level in E. coli but not S. cerevisiae

Meer, K. M.; Nelson, P. G.; Xiong, K.; Masel, J.

10.1101/554329 — evolutionary biology — Posted on 2019-02-19

1011 Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth

Shah, K.; Whitaker, R. H.; Busby, T.; Hu, J.; Shi, B.; Wang, Z.; Zang, C.; Placzek, W. J.; Jiang, H.

10.1101/554386 — cancer biology — Posted on 2019-02-19

1012 Non-catalytic binding sites induce weaker long-range evolutionary rate gradients than catalytic sites in enzymes

Sharir-Ivry, A.; Xia, Y.

10.1101/554436 — evolutionary biology — Posted on 2019-02-19

1013 Immunohistochemical and ultrastructural analysis of the maturing larval zebrafish enteric nervous system reveals the formation of a neuropil pattern

Baker, P. A.; Meyer, M. D.; Tsang, A.; Uribe, R.

10.1101/555094 — developmental biology — Posted on 2019-02-19

1014 BioCell2XML: A novel tool for converting cell lineage data from SIMI BioCell to MaMuT (Fiji)

Pennerstorfer, M.; Loose, G.; Wolff, C.

10.1101/554873 — developmental biology — Posted on 2019-02-19

1015 Auto-inhibition of myoblast fusion by cyclic receptor signalling.

Sieiro, D.; Melendez, J.; Morin, V.; Salgado, D.; Marcelle, C.

10.1101/553420 — developmental biology — Posted on 2019-02-19

1016 Varying crosslinking motifs drive the mesoscale mechanics of actin-microtubule composites

Ricketts, S. N.; Francis, M. L.; Farhadi, L.; Rust, M. J.; Das, M.; Ross, J. L.; Robertson-Anderson, R. M.

10.1101/554584 — biophysics — Posted on 2019-02-19

1017 EWAS-Galaxy: a tools suite for population epigenetics integrated into Galaxy

Murat, K.; Gruning, B.; Poterlowicz, P. W.; Westgate, G.; Tobin, D. J.; Poterlowicz, K.

10.1101/553784 — bioinformatics — Posted on 2019-02-19

1018 A primer on high-dimensional data analysis workflows for studying visual cortex development and plasticity

Balsor, J. L.; Jones, D. G.; Murphy, K. M.

10.1101/554378 — neuroscience — Posted on 2019-02-19

1019 The Multidimensional Battery of Prosody Perception (MBOPP)

Jasmin, K.; Dick, F.; Tierney, A.

10.1101/555102 — neuroscience — Posted on 2019-02-19

1020 Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells

Dhalla, F.; Baran-Gale, J.; Maio, S.; Chappell, L.; Hollander, G. A.; Ponting, C.

10.1101/554899 — immunology — Posted on 2019-02-19

1021 Intra- and Inter-Specific Investigations of Skeletal DNA Methylation Patterns and Femur Morphology in Nonhuman Primates

Housman, G.; Quillen, E. E.; Stone, A. C.

10.1101/554618 — genomics — Posted on 2019-02-19

1022 Epigenome-wide response to oil pollution in the foundation plant Spartina alterniflora

Alvarez, M.; Robertson, M.; van Gurp, T.; Wagemaker, N.; Giraud, D.; Ainouche, M.; Salmon, A.; Verhoeven, K.; Richards, C.

10.1101/426569 — ecology — Posted on 2019-02-19

1023 On the front line of Klebsiella pneumoniae surface structures understanding: establishment of Fourier Transform Infrared (FT-IR) spectroscopy as a capsule typing method

Rodrigues, C.; Sousa, C.; Lopes, J.; Novais, A.; Peixe, L.

10.1101/554816 — developmental biology — Posted on 2019-02-19

1024 Caenorhabditis elegans locomotion is affected by internalized paramagnetic nanoparticles in the presence of magnetic field

Gourgou, E.; Zhang, Y.; Mirzakhalili, E.; Epureanu, B.

10.1101/248369 — biophysics — Posted on 2019-02-19

1025 The carboxyl-terminal sequence of Bim enables Bax activation and killing of unprimed cells

Chi, X.; Pemberton, J.; Nguyen, D.; Osterlund, E. J.; Liu, Q.; Brahmbhatt, H.; Zhang, Z.; Lin, J.; Leber, B.; Andrews, D.

10.1101/554907 — biochemistry — Posted on 2019-02-19

1026 Malignant liver cancers have distinct myeloid-derived suppressor cell signatures

Bayik, D.; Serbinowski, E.; Lauko, A.; Roversi, G. A.; Acevedo-Moreno, L.-A.; Lanigan, C.; Orujov, M.; Silver, D. J.; Brown, J. M.; Allende, D. S.; Aucejo, F. N.; Lathia, J. D.

10.1101/554600 — pathology — Posted on 2019-02-19

1027 The Role of Emotions in Moral Judgments: Time-resolved evidence from event-related brain potentials

Demel, R.; Waldmann, M. R.; Schacht, A.

10.1101/541342 — neuroscience — Posted on 2019-02-19

1028 Constrained inference in sparse coding reproduces contextual effects and predicts laminar neural dynamics

Capparelli, F.; Pawelzik, K.; Ernst, U.

10.1101/555128 — neuroscience — Posted on 2019-02-19

1029 The inducible response of the nematode Caenorhabditis elegans to members of its natural microbiome across development and adult life

Yang, W.; Petersen, C.; Pees, B.; Zimmermann, J.; Washina, S.; Dirksen, P.; Rosenstiel, P.; Tholey, A.; Leippe, M.; Dierking, K.; Kaleta, C.; Schulenburg, H.

10.1101/554758 — evolutionary biology — Posted on 2019-02-19

1030 Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation

Kirkup, B.; McKee, A.; Makin, K.; Paveley, J.; Caim, S.; Alcon-Giner, C.; Leclaire, C.; Dalby, M.; Le Gall, G.; Andrusaite, A.; Kreuzaler, P.; Driscoll, P.; MacRae, J.; Calvani, E.; Ghanate, A.; Milling, S.; Yuneva, M.; Weilbaecher, K.; Korcsmaros, T.; Hall, L. J.; Robinson, S. D.

10.1101/553602 — cancer biology — Posted on 2019-02-19

1031 KAP1 is an antiparallel dimer with a natively functional asymmetry

Fonti, G.; Marcaida, M.; Bryan, L.; Traeger, S.; Kalantzi, A.; Helleboid, P.-Y.; Demurtas, D.; Tully, M.; Grudinin, S.; Trono, D.; Fierz, B.; Dal Peraro, M.

10.1101/553511 — biophysics — Posted on 2019-02-19

1032 Objective Assessment of Beat Quality in Transcranial Doppler Measurement of Blood Flow Velocity in Cerebral Arteries

Jalaleddini, K.; Canac, N.; Thorpe, S. G.; Delay, B.; Dorn, A. Y.; Scalzo, F.; Thibeault, C. M.; Wilk, S.; Hamilton, R. B.

10.1101/554568 — bioinformatics — Posted on 2019-02-19

1033 dbMTS: a comprehensive database of putative human microRNA target site SNVs and their functional predictions

Li, C.; Swartz, M. D.; Yu, B.; Liu, X.

10.1101/554485 — bioinformatics — Posted on 2019-02-19

1034 Regulation of food intake by astrocytes in the brainstem dorsal vagal complex

MacDonald, A. J.; Holmes, F. E.; Beall, C.; Pickering, A. E.; Ellacott, K. L.

10.1101/543991 — neuroscience — Posted on 2019-02-19

1035 The impact of distillery effluent irrigation on plant-growth-promoting traits and taxonomic composition of bacterial communities in agricultural soil

Kumari, P.; Tripathi, B. M.; Singh, R. N.; Saxena, A. K.; Kaushik, R.

10.1101/554709 — microbiology — Posted on 2019-02-19

1036 B cell tetherin: a flow-cytometric cell-specific assay for response to Type-I interferon predicts clinical features and flares in SLE

El-Sherbiny, Y. M.; Md Yusof, M. Y.; Psarras, A.; Hensor, E. M. A.; Kabba, K. Z.; Dutton, K.; Mohamed, A. A. A.; Elewaut, D.; McGonagle, D.; Tooze, R.; Doody, G.; Wittmann, M.; Emery, P.; Vital, E.

10.1101/554352 — immunology — Posted on 2019-02-19

1037 De novo mutations across 1,465 diverse genomes reveal novel mutational insights and reductions in the Amish founder population.

Kessler, M. D.; Loesch, D. P.; Perry, J. A.; Heard-Costa, N. L.; Cade, B. E.; Wang, H.; Daya, M.; Ziniti, J.; Datta, S.; Celedon, J. C.; Soto-Quiros, M. E.; Avila, L.; Weiss, S. T.; Barnes, K.; Redline, S. S.; Vasan, R.; Johnson, A. D.; Mathias, R. A.; Hernandez, R.; Wilson, J. G.; Nickerson, D. A.; Abecasis, G.; Browning, S. R.; Sebastian Zoellner, S.; O'Connell, J. R.; Mitchell, B. D.; O'Connor, T. D.

10.1101/553214 — genetics — Posted on 2019-02-19

1038 Anticipation of a serial transfer protocol through the evolution of fine-tuned growth dynamics

van Dijk, B.; Meijer, J.; Cuypers, T. D.; Hogeweg, P.

10.1101/554766 — evolutionary biology — Posted on 2019-02-19

1039 Prey abundance drives habitat occupancy by jaguars in Amazonian floodplain fluvial islands

Rabelo, R. M.; Aragon, S.; Bicca-Marques, J. C.

10.1101/555052 — ecology — Posted on 2019-02-19

1040 Comparing 3D genome organization in multiple species using Phylo-HMRF

Yang, Y.; Zhang, Y.; Ren, B.; Dixon, J.; Ma, J.

10.1101/552505 — bioinformatics — Posted on 2019-02-19

1041 An Array of 60,000 Antibodies for Proteome-Scale Antibody Generation and Target Discovery

Wang, Z.; Li, Y.; Hou, B.; Pronobis, M. I.; Wang, Y.; Wang, M.; Cheng, G.; Zhang, Z.; Weng, W.; Wang, Y.; Tang, Y.; Xu, X.; Pan, R.; Lin, F.; Wang, N.; Chen, Z.; Wang, S.; Ma, L. z.; Li, Y.; Huang, D.; Jiang, L.; Wang, Z.; Zeng, W.; Zhang, Y.; Du, X.; Lin, Y.; Li, Z.; Xia, Q.; Geng, J.; Dai, H.; Wang, C.; Yu, Y.; Zhao, X.; Yuan, Z.; Yan, J.; Ren, B.; Nie, Q.; Zhang, X.; Wang, K.; Chen, F.; Zhang, Q.; Zhu, Y.; Poss, K. D.; Tao, S.; Meng, X.

10.1101/553339 — systems biology — Posted on 2019-02-19

1042 LRRK2-mediated phosphorylation of HDAC6 regulates HDAC6-cytoplasmic dynein interaction and aggresome formation.

Lucas, R. M.; Bauer, C. S.; Chinnaiya, K.; Schwartzentruber, A.; MacDonald, R.; Collins, M. O.; Aasly, J. O.; Bronstad, G.; Ferraiuolo, L.; Mortiboys, H.; De Vos, K.

10.1101/554881 — neuroscience — Posted on 2019-02-19

1043 Principles Governing the Dynamics of GABAergic Interneurons in the Barrel Cortex

Yu, J.; Hu, H.; Agmon, A.; Svoboda, K.

10.1101/554949 — neuroscience — Posted on 2019-02-19

1044 Optimization of graph construction can significantly increase the power of structural brain network studies

Messaritaki, E.; Dimitriadis, S. I.; Jones, D. K.

10.1101/553743 — neuroscience — Posted on 2019-02-19

1045 Evaluating brain cell marker genes based on differential gene expression and co-expression

Dai, R.; Chen, Y.; Jiao, C.; Dai, J.; Chen, C.; Liu, C.

10.1101/554626 — neuroscience — Posted on 2019-02-19

1046 Multiple evolutionary trajectories for non-O157 Shiga toxigenic Escherichia coli

Alikhan, N.-F.; Bachmann, N. L.; Ben Zakour, N. L.; Petty, N. K.; Stanton-Cook, M.; Gawthorne, J. A.; Cobbold, R.; Schembri, M. A.; Beatson, S. A.

10.1101/549998 — microbiology — Posted on 2019-02-19

1047 Detection of low-density Plasmodium falciparum infections using amplicon deep sequencing

Early, A. M.; Daniels, R. F.; Farrell, T. M.; Grimsby, J.; Volkman, S. K.; Wirth, D. F.; MacInnis, B. L.; Neafsey, D. E.

10.1101/453472 — microbiology — Posted on 2019-02-19

1048 The functional repertoire encoded within the native microbiome of the model nematode Caenorhabditis elegans

Zimmermann, J.; Obeng, N.; Yang, W.; Pees, B.; Petersen, C.; Washina, S.; Kissoyan, K. A.; Aidley, J.; Hoeppner, M. P.; Bunk, B.; Sproer, C.; Leippe, M.; Dierking, K.; Kaleta, C.; Schulenburg, H.

10.1101/554345 — microbiology — Posted on 2019-02-19

1049 Transcript expression-aware annotation improves rare variant discovery and interpretation

Cummings, B. B.; Karczewski, K. J.; Kosmicki, J. A.; Seaby, E. G.; Watts, N. A.; Singer-Berk, M.; Mudge, J. M.; Karjalainen, J.; Satterstrom, K. F.; ODonnell-Luria, A.; Poterba, T.; Seed, C.; Solomonson, M.; Alfoldi, J.; The Genome Aggregation Database Production Team, ; The Genome Aggregation Database Consortium, ; Daly, M. J.; MacArthur, D. G.

10.1101/554444 — genomics — Posted on 2019-02-19

1050 The Drosophila melanogaster PIF1 helicase promotes survival during replication stress and processive DNA synthesis during double-strand gap repair

McVey, M.; Kocak, E.; Dykstra, S.; Nemeth, A.; Coughlin, C. G.; Rodgers, K.

10.1101/554550 — genetics — Posted on 2019-02-19

1051 Limits to environmental masking of genetic quality in sexual signals

Howie, J. M.; Dawson, H. A. C.; Pomiankowski, A.; Fowler, K.

10.1101/554477 — evolutionary biology — Posted on 2019-02-19

1052 Temperature-dependent changes to host-parasite interactions alter the thermal performance of a bacterial host.

Padfield, D.; Castledine, M.; Buckling, A.

10.1101/554717 — evolutionary biology — Posted on 2019-02-19

1053 Using transfer learning on whole slide images to predict tumor mutational burden in bladder cancer patients

Xu, H.; Park, S.; Lee, S. H.; Hwang, T. H.

10.1101/554527 — bioinformatics — Posted on 2019-02-19

1054 fastq-pair: efficient synchronization of paired-end fastq files

Edwards, R.; Edwards, J. A.

10.1101/552885 — bioinformatics — Posted on 2019-02-19

1055 Anti-biofilm Activity of Graphene Quantum Dots via Self-Assembly with Bacterial Amyloid Proteins

Wang, Y.; Kadiyala, U.; Qu, Z.; Elvati, P.; Altheim, C.; Kotov, N. A.; Violi, A.; VanEpps, J. S.

10.1101/550285 — bioengineering — Posted on 2019-02-19

1056 Delivering on the Vision of Bench to Bedside: A Rare Disease Funding Community Collaboration to Develop Effective Therapies for Neurofibromatosis Type 1 Tumors

La Rosa, S.; Browder, V.; Bakker, A. C.; Blakeley, J. O.; Verma, S. K.; Wong, L. M.; Morris, J. A.; Bora, N.

10.1101/552976 — scientific communication and education — Posted on 2019-02-19

1057 Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment

Engelsdorf, T.; Kjaer, L.; Gigli-Bisceglia, N.; Vaahtera, L.; Bauer, S.; Miedes, E.; Wormit, A.; James, L.; Chairam, I.; Molina, A.; Hamann, T.

10.1101/552893 — plant biology — Posted on 2019-02-19

1058 Metabolomic profiling revels systemic signatures of premature aging induced by Hutchinson-Gilford Progeria Syndrome

Monnerat, G.; Evaristo, G.; Evaristo, J.; Santos, C.; Reis, G.; Maciel, L.; Carvalho, V.; Nogueira, F. C.; Domont, G. B.; Campos de Carvalho, A. C.

10.1101/554220 — pathology — Posted on 2019-02-19

1059 Chromosomal rearrangements at hypomethylated Satellite 2 sequences are associated with impaired replication efficiency and increased fork stalling

Delpu, Y.; McNamara, T. F.; Griffin, P.; Kaleem, S.; Narayan, S.; Schildkraut, C.; Miga, K. H.; Tahiliani, M.

10.1101/554410 — molecular biology — Posted on 2019-02-19

1060 RNAseq profiling of leukocyte populations in zebrafish larvae reveals a cxcl11 chemokine gene as a marker of macrophage polarization during mycobacterial infection.

Rougeot, J.; Torraca, V.; Zakrzewska, A.; Kanwal, Z.; Jansen, H.; Spaink, H. P.; Meijer, A. H.

10.1101/554808 — immunology — Posted on 2019-02-19

1061 Quantifying coral morphology

Zawada, K. J. A.; Dornelas, M.; Madin, J. S.

10.1101/553453 — ecology — Posted on 2019-02-19

1062 Control of Hematopoietic Stem Cell Function Through Epigenetic Regulation of Energy Metabolism and Genome Integrity

Yang, Z.; Shah, K.; Khodadadi-Jamayran, A.; Jiang, H.

10.1101/554519 — developmental biology — Posted on 2019-02-19

1063 Conditional Prediction of RNA Secondary Structure Using NMR Chemical Shifts

Zhang, K.; Frank, A. T.

10.1101/554931 — biophysics — Posted on 2019-02-19

1064 Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria

Edwards, H. S.; Krishnakumar, R.; Sinha, A.; Bird, S. W.; Patel, K. D.; Bartsch, M. S.

10.1101/460014 — bioinformatics — Posted on 2019-02-19

1065 Systematic spatio-temporal mapping reveals divergent cell death pathways in three mouse models of hereditary retinal degeneration

Power, M. J.; Rogerson, L. E.; Schubert, T.; Berens, P.; Euler, T.; Paquet-Durand, F.

10.1101/554733 — neuroscience — Posted on 2019-02-19

1066 Differential immune gene expression associated with contemporary range expansion of two invasive rodents in Senegal

Charbonnel, N.; Galan, M.; Tatard, C.; Loiseau, A.; Diagne, C. A.; Dalecky, A.; Parrinello, H.; Rialle, S.; Severac, D.; Brouat, C.

10.1101/442160 — ecology — Posted on 2019-02-19

1067 Pixel: a content management platform for quantitative omics data

Denecker, T.; Durand, W.; Maupetit, J.; Hebert, C.; Camadro, J.-M.; Poulain, P.; Lelandais, G.

10.1101/427724 — bioinformatics — Posted on 2019-02-19

1068 Impaired cognitive performance under psycho-social stress in cannabis-dependent males is mediated by attenuated precuneus activity

Zhao, W.; Zimmermann, K.; Zhou, X.; Zhou, F.; Fu, M.; Dernbach, C.; Scheele, D.; Weber, B.; Eckstein, M.; Hurlemann, R.; Kendrick, K.; Becker, B.

10.1101/429951 — neuroscience — Posted on 2019-02-19

1069 A single cell transcriptional roadmap for cardiopharyngeal fate diversification

Wang, W.; Niu, X.; Stuart, T.; Jullian, E.; Mauck, W.; Kelly, R. G.; Satija, R.; Christiaen, L.

10.1101/150235 — developmental biology — Posted on 2019-02-19

1070 Nystagmus in patients with congenital stationary night blindness (CSNB) originates from synchronously firing direction-selective retinal ganglion cells

Winkelman, B. H. J.; Howlett, M. H.; Holzel, M.-B.; Joling, C.; Fransen, K. H.; Pangeni, G.; Kamermans, S.; Sakuta, H.; Noda, M.; Simonsz, H. J.; McCall, M. A.; De Zeeuw, C. I.; Kamermans, M.

10.1101/555011 — neuroscience — Posted on 2019-02-19

1071 Parental Allele-Specific Protein Expression in Single Cells In Vivo

Lo, C.-A.; Chen, B.

10.1101/413849 — cell biology — Posted on 2019-02-19

1072 Neutrophil-extracellular trap-associated RNA (naRNA) and LL37 enable self-amplifying inflammation in psoriasis

Herster, F.; Bittner, Z.; Dickhoefer, S.; Eisel, D.; Eigenbrod, T.; Knorpp, T.; Schneiderhan-Marra, N.; Loeffler, M. W.; Kalbacher, H.; Hartl, D.; Freund, L.; Schaekel, K.; Heiser, M.; Ghoreschi, K.; Weber, A. N. R.

10.1101/324814 — immunology — Posted on 2019-02-19

1073 The oncoprotein DEK affects the outcome of PARP1/2 inhibition during replication stress

Ferrando-May, E.; Ganz, M.; Vogel, C.; Czada, C.; Jörke, V.; Kleiner, R.; Pierzynska-Mach, A.; Zanacchi, F. C.; Diaspro, A.; Kappes, F.; Bürkle, A.

10.1101/555003 — cancer biology — Posted on 2019-02-19

1074 The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

Pervolaraki, E.; Tyson, A. L.; Pibiri, F.; Poulter, S. L.; Reichelt, A. C.; Rodgers, R. J.; Clapcote, S. J.; Lever, C.; Andreae, L. C.; Dachtler, J.

10.1101/300806 — neuroscience — Posted on 2019-02-19

1075 Magnitude and correlates of caesarean section in urban and rural areas: A multivariate study in Vietnam

de Loenzien, M.; Schantz, C.; Luu, N. B.; Dumont, A.

10.1101/554964 — epidemiology — Posted on 2019-02-19

1076 Disease spectrum and outcomes among elderly patients in two tertiary hospitals in Dar es Salaam, Tanzania

Tumaini, B. B.; Munseri, P.; Pallangyo, K.

10.1101/554972 — epidemiology — Posted on 2019-02-19

1077 Adapted dandelions increase seed dispersal when they are attacked by root herbivores

Bont, Z.; Pfander, M.; Robert, C. A. M.; Huber, M.; Poelman, E. H.; Raaijmakers, C. E.; Erb, M.

10.1101/551630 — ecology — Posted on 2019-02-19

1078 A novel population of long-range inhibitory neurons

Christenson Wick, Z.; Tetzlaff, M. R.; Krook-Magnuson, E.

10.1101/554360 — neuroscience — Posted on 2019-02-19

1079 Arabidopsis and Chlamydomonas phosphoribulokinase crystal structures complete the redox structural proteome of the Calvin-Benson cycle

Gurrieri, L.; Del Giudice, A.; Demitri, N.; Falini, G.; Pavel, N. V.; Zaffagnini, M.; Polentarutti, M.; Crozet, P.; Marchand, C.; Henri, J.; Trost, P.; Lemaire, S.; Sparla, F.; Fermani, S.

10.1101/422709 — plant biology — Posted on 2019-02-18

1080 A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells

Shah, K.; King, G. D.; Jiang, H.

10.1101/554535 — developmental biology — Posted on 2019-02-18

1081 Bat-fruit networks structure resist habitat modification but species roles change in the most transformed habitats

Castano, J. H.; Carranza-Quiceno, J. A.; Perez-Torres, J.

10.1101/554246 — ecology — Posted on 2019-02-18

1082 Nocturnal scent in a 'bird-fig': a cue to attract bats as additional dispersers?

Ripperger, S. P.; Rehse, S.; Wacker, S.; Kalko, E.; Schulz, S.; Rodriguez-Herrera, B.; Ayasse, M.

10.1101/418970 — ecology — Posted on 2019-02-18

1083 Pathogen-induced pH changes regulate the growth-defense balance of plants

Kesten, C.; Gamez-Arjona, F. M.; Scholl, S.; Menna, A.; Dora, S.; Huerta, A. I.; Huang, H.-Y.; Tintor, N.; Kinoshita, T.; Rep, M.; Krebs, M.; Schumacher, K.; Sanchez-Rodriguez, C.

10.1101/550491 — plant biology — Posted on 2019-02-18

1084 Human Cytomegalovirus Genomes Sequenced Directly from Clinical Material: Variation, Multiple-Strain Infection, Recombination and Mutation

Suarez, N. M.; Wilkie, G. S.; Hage, E.; Camiolo, S.; Holton, M.; Hughes, J.; Maabar, M.; Sreenu, V. B.; Dhingra, A.; Gompels, U. A.; Wilkinson, G. W.; Baldanti, F.; Milena, F.; Lilleri, D.; Arossa, A.; Ganzenmueller, T.; Gerna, G.; Hubacek, P.; Schulz, T. F.; Wolf, D.; Zavattoni, M.; Davison, A. J.

10.1101/505735 — microbiology — Posted on 2019-02-18

1085 Cryptococcus neoformans resist to drastic conditions by switching to viable but non-culturable cell phenotype

Hommel, B.; Sturny-Leclere, A.; Volant, S.; Veluppillai, N.; Duchateau, M.; Yu, C.-H.; Hourdel, V.; Varet, H.; Matondo, M.; Perfect, J. R.; Casadevall, A.; Dromer, F.; Alanio, A.

10.1101/552836 — microbiology — Posted on 2019-02-18

1086 Window to the Fluorescence: The White Eye-Color Gene of Western Corn Rootworm, Diabrotica virgifera virgifera

Grubbs, N.; Chu, F.-C.; Lorenzen, M.

10.1101/552935 — genetics — Posted on 2019-02-18

1087 The intersectional genetics landscape for human

Macedo, A.; Gontijo, A. M.

10.1101/552984 — bioinformatics — Posted on 2019-02-18

1088 Teachers' approaches to genetics teaching mirror their choice of content and avoidance of sensitive issues

Aivelo, T.; Uitto, A.

10.1101/350710 — scientific communication and education — Posted on 2019-02-18

1089 Black sea cucumber (Holothuria atra Jaeger, 1833) protects Caenorhabditis elegans against Pseudomonas aeruginosa infection

Lee, W.-T.; Tan, B.-K.; Eng, S.-A.; Yuen, G. C.; Chan, K. L.; Sim, Y. K.; Sulaiman, S. F.; Chong, A. S.-C.

10.1101/515783 — pharmacology and toxicology — Posted on 2019-02-18

1090 Spatial signature of white matter hyperintensities in stroke patients

Schirmer, M. D.; Giese, A.-K.; Fotiadis, P.; Etherton, M. R.; Cloonan, L.; Viswanathan, A.; Greenberg, S. M.; Wu, O.; Rost, N. S.

10.1101/457374 — neuroscience — Posted on 2019-02-18

1091 Polygenic Prediction via Bayesian Regression and Continuous Shrinkage Priors

Ge, T.; Chen, C.-Y.; Ni, Y.; Feng, Y.-C. A.; Smoller, J. W.

10.1101/416859 — genetics — Posted on 2019-02-18

1092 The role of p-21 activated kinases (PAKs) in glucose homeostasis and skeletal muscle glucose uptake

Moller, L. L. V.; Jaurji, M.; Nielsen, I. L.; Joseph, G. A.; Kjobsted, R.; Knudsen, J. R.; Madsen, A. B.; Schjerling, P.; Jensen, T. E.; Krauss, R. S.; Richter, E. A.; Sylow, L.

10.1101/543736 — cell biology — Posted on 2019-02-18

1093 A Heuristic Derived from Analysis of the Ion Channel Structural Proteome Permits the Rapid Identification of Hydrophobic Gates

Rao, S.; Klesse, G.; Stansfeld, P. J.; Tucker, S. J.; Sansom, M. S. P.

10.1101/498386 — biophysics — Posted on 2019-02-18

1094 Gaussian Process Based Heteroscedastic Noise Modeling for Tumor Mutation Burden Prediction from Whole Slide Images

Park, S.; Xu, H.; Hwang, T. H.

10.1101/554261 — bioinformatics — Posted on 2019-02-18

1095 The human non-visual opsin OPN3 regulates pigmentation of epidermal melanocytes through interaction with MC1R

Ozdeslik, R. N.; Olinski, L. E.; Trieu, M. M.; Oprian, D. D.; Oancea, E.

10.1101/552851 — physiology — Posted on 2019-02-18

1096 rSeqTU -- a machine-learning based R package for prediction of bacterial transcription units

Niu, S.-Y.; Liu, B.; Ma, Q.; Chou, W.-C.

10.1101/553057 — bioinformatics — Posted on 2019-02-18

1097 A cytoskeletal network maintains filament shape in the multicellular cyanobacterium Anabaena sp. PCC 7120

Springstein, B. L.; Nürnberg, D. J.; Kieninger, A.-K.; Woehle, C.; Weissenbach, J.; Theune, M.; Helbig, A. O.; Tholey, A.; Maldener, I.; Dagan, T.; Stucken, K.

10.1101/553073 — microbiology — Posted on 2019-02-18

1098 Screening of antimicrobial activity and polyketide synthase gene identification from the Actinomycetes isolates

Srivastav, A.; Shanmugaiah, V.

10.1101/396846 — microbiology — Posted on 2019-02-18

1099 Modelling the Perception of Colour Patterns in Vertebrates with HMAX

Renoult, J. P.; Guyl, B.; Mendelson, T. C.; Percher, A.; Dorignac, J.; Geniet, F.; Molino, F.

10.1101/552307 — evolutionary biology — Posted on 2019-02-18

1100 In silico analysis of IDH3A gene revealed Novel mutations associated with Retinitis Pigmentosa

Mahmoud, T. A.; Abdelmoneim, A. H.; Murshed, N. S.; Mohammed, Z. O.; Ahmed, D. T. E.; Altyeb, F. A.; Mahmoud, N. A.; Mohammed, M. A.; Arayah, F. A.; Mohammed, W. I.; Abayazed, O. S.; Akasha, A. S.; Mustafa, M. I.; Hassan, M. A.

10.1101/554196 — bioinformatics — Posted on 2019-02-18

1101 NanoR: An user-friendly R package to analyze and compare nanopore sequencing data

Bolognini, D.; Bartalucci, N.; Mingrino, A.; Vannucchi, A. M.; Magi, A.

10.1101/514232 — bioinformatics — Posted on 2019-02-18

1102 Protein Condensates with Appropriate Material Properties Regulate Tumorigenesis

Li, W.; Hu, J.; Shi, B.; Jiang, H.

10.1101/536839 — biochemistry — Posted on 2019-02-18

1103 Distinct Regulaton of Bioenergetics and Translation by Gp I mGluRs and NMDARs

Ghosh Dastidar, S.; Chakraborty, S.; Bhattacharya, A.; Chattarji, S.; Muddashetty, R.

10.1101/552638 — neuroscience — Posted on 2019-02-18

1104 Paralog dependency indirectly affects the robustness of human cells

Dandage, R.; Landry, C. R.

10.1101/552208 — evolutionary biology — Posted on 2019-02-18

1105 The elusive actin cytoskeleton of a green alga expressing both conventional and divergent actins

Craig, E. W.; Mueller, D. M.; Schaffer, M.; Engel, B. D.; Avasthi, P.

10.1101/554279 — cell biology — Posted on 2019-02-18

1106 Mitf links neuronal activity and long-term homeostatic intrinsic plasticity

Atacho, D.; Reynisson, H.; Peturdottir, A. T.; Eysteinsson, T.; Steingrimsson, E.; Petersen, P.

10.1101/507640 — neuroscience — Posted on 2019-02-18

1107 \"Self-inactivating\" rabies viruses are just first-generation, ΔG rabies viruses

Matsuyama, M.; Jin, L.; Lavin, T. K.; Sullivan, H. A.; Hou, Y.; Lea, N. E.; Pruner, M. T.; Dam Ferdinez, M. L.; Wickersham, I. R.

10.1101/550640 — neuroscience — Posted on 2019-02-18

1108 Disentangling semantic and response learning effects in color-word contingency learning

Geukes, S.; Vorberg, D.; Zwitserlood, P.

10.1101/546689 — neuroscience — Posted on 2019-02-18

1109 Gene-Set Enrichment with Mathematical Biology (GEMB)

Cochran, A.; Forger, D.; Zöllner, S.; McInnis, M.

10.1101/554212 — genetics — Posted on 2019-02-18

1110 Metagenomic analysis reveals large potential for carbon, nitrogen and sulfur cycling in coastal methanic sediments of the Bothnian Sea

Rasigraf, O.; van Helmond, N. A. G. M.; Frank, J.; Lenstra, W. K.; Egger, M.; Slomp, C. P.; Jetten, M. S. M.

10.1101/553131 — ecology — Posted on 2019-02-18

1111 Comprehensive Assessment of Sequence and Expression of Circular-RNAs in Progenitor Cell Types of the Developing Mammalian Cortex

Dori, M.; Haj Abdullah Alieh, L.; Cavalli, D.; Massalini, S.; Lesche, M.; Dahl, A.; Calegari, F.

10.1101/553495 — developmental biology — Posted on 2019-02-18

1112 HEXOKINASE 1 Glycolytic Action Fuels Post-Germinative Seedling Growth

Ganpudi, A.; Romanowski, A.; Halliday, K. J.

10.1101/548990 — plant biology — Posted on 2019-02-18

1113 Draft Genome Assembly and Annotation of Red Raspberry Rubus Idaeus

Wight, H.; Zhou, J.; Li, M.; Hannenhalli, S.; Mount, S.; Liu, Z.

10.1101/546135 — genomics — Posted on 2019-02-18

1114 Evolutionary dynamics determines adaptation to inactivation of an essential gene.

Rodrigues, J. V.; Shakhnovich, E.

10.1101/552240 — evolutionary biology — Posted on 2019-02-18

1115 Sex-biased gene expression is masculinized in asexual females

Parker, D. J.; Bast, J.; Jalvingh, K.; Dumas, Z.; Robinson-Rechavi, M.; Schwander, T.

10.1101/553172 — evolutionary biology — Posted on 2019-02-18

1116 The Hunchback temporal transcription factor determines motor neuron axon and dendrite targeting in Drosophila

Seroka, A. Q.; Doe, C. Q.

10.1101/554188 — neuroscience — Posted on 2019-02-18

1117 The essential role played by B cells in supporting protective immunity against Trichuris muris infection is dependent on host genetic background and is independent of antibody

Sahputra, R.; Ruckerl, D.; Couper, K.; Muller, W.; Else, K.

10.1101/550434 — immunology — Posted on 2019-02-18

1118 Anti-Asialo GM1 treatment during secondary Toxoplasma gondii infection is lethal and depletes T cells

Ivanova, D. L.; Denton, S. L.; Gigley, J.

10.1101/550608 — immunology — Posted on 2019-02-18

1119 Divergence in Thermostability of Arabidopsis Mitochondrial Nucleotide Exchange Factors Encoded by Duplicate Genes, MGE1 and MGE2

Chen, Z.-t.; Hung, M.-J.; Yu, S.-J.; Liao, T.-Y.; Lin, Y.-P.; Chen, R. P.- Y.; Yang, C.-C.; Charng, Y.-y.

10.1101/553503 — evolutionary biology — Posted on 2019-02-18

1120 Adaptive introgression during environmental change can weaken reproductive isolation

Owens, G. L.; Samuk, K.

10.1101/553230 — evolutionary biology — Posted on 2019-02-18

1121 Repeated evolution of asymmetric genitalia and right-sided mating behavior in the Drosophila nannoptera species group

Acurio, A.; Rhebergen, F. T.; Paulus, S. E.; Courtier-Orgogozo, V.; Lang, M.

10.1101/553024 — evolutionary biology — Posted on 2019-02-18

1122 Reliable analysis of clinical tumor-only whole exome sequencing data

Oh, S.; Geistlinger, L.; Ramos, M.; Morgan, M.; Waldron, L.; Riester, M.

10.1101/552711 — bioinformatics — Posted on 2019-02-18

1123 A High-Resolution Head and Brain Computer Model for Forward and Inverse EEG Simulation

Warner, A.; Tate, J.; Burton, B.; Johnson, C. R.

10.1101/552190 — bioengineering — Posted on 2019-02-18

1124 Visualizing Conformational Transitions of the Lipid II Flippase MurJ

Lee, S.-Y.; Kuk, C. Y.; Hao, A.; Guan, Z.

10.1101/552745 — biochemistry — Posted on 2019-02-18

1125 The benefits of insect-swarm hunting in echolocating bats, and its influence on the evolution of bat echolocation signals

Boonman, A.; Yovel, Y.; Fenton, B.

10.1101/554055 — animal behavior and cognition — Posted on 2019-02-18

1126 The foveal visual representation of the primate superior colliculus

Chen, C.-Y.; Hoffmann, K.-P.; Distler, C.; Hafed, Z.

10.1101/554121 — neuroscience — Posted on 2019-02-18

1127 Hippocampal and neocortical oscillations are tuned to behavioral state in freely-behaving macaques

Talakoub, O.; Sayegh, P. F.; Womelsdorf, T.; Zinke, W.; Fries, P.; Lewis, C. M.; Hoffman, K. L.

10.1101/552877 — neuroscience — Posted on 2019-02-18

1128 Mechanics of DNA Replication and Transcription Guide the Asymmetric Distribution of RNAPol2 and New Nucleosomes on Replicated Daughter Genomes

Ziane, R.; Camasses, A.; Radman-Livaja, M.

10.1101/553669 — molecular biology — Posted on 2019-02-18

1129 Robust archaeal and bacterial communities inhabit shallow subsurface sediments of the Bonneville Salt Flats

McGonigle, J. M.; Bernau, J. A.; Bowen, B. B.; Brazelton, W.

10.1101/553032 — microbiology — Posted on 2019-02-18

1130 Regulation of bacterial surface attachment by a network of sensory transduction proteins

Reyes Ruiz, L. M.; Fiebig, A.; Crosson, S.

10.1101/554154 — microbiology — Posted on 2019-02-18

1131 Resident memory CD8 T cells persist for years in human small intestine

10.1101/553792 — immunology — Posted on 2019-02-18

1132 The distribution of fitness effects among synonymous mutations in a gene under selection

Kassen, R.; Lebeuf-Taylor, E.; McCloskey, N.; Hinz, A.; Bailey, S.

10.1101/553610 — evolutionary biology — Posted on 2019-02-18

1133 Additional layer of regulation via convergent gene orientation in yeasts

Gilet, J.; Conte, R.; Torchet, C.; Benard, L.; Ingrid, L.

10.1101/551689 — evolutionary biology — Posted on 2019-02-18

1134 Accurate Fetal Variant Calling in the Presence of Maternal Cell Contamination

Nabieva, E.; Mishra Sharma, S.; Kapushev, Y.; Garushyans, S. K.; Fedotova, A. V.; Moskalenko, V. N.; Kanivets, I. V.; Pyankov, D. V.; Neretina, T. V.; Logacheva, M. D.; Bazykin, G. A.; Yarotsky, D.

10.1101/552414 — bioinformatics — Posted on 2019-02-18

1135 In-silico predictive identification of K-RasG12V inhibitors in natural compounds

Aliyar, M.; Aryapour, H.; Mahdavi, M.

10.1101/553149 — bioinformatics — Posted on 2019-02-18

1136 ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning

Ruiz-Reche, A.; Indi, J. A.; de la Rubia, I.; Eyras, E.

10.1101/553321 — bioinformatics — Posted on 2019-02-18

1137 Neural network-based alterations during repeated heat pain stimulation in major depression

Bilek, E.; Zang, Z.; Wolf, I.; Henrich, F.; Moessnang, C.; Braun, U.; Treede, R.-D.; Magerl, W.; Meyer-Lindenberg, A.; Tost, H.

10.1101/553842 — neuroscience — Posted on 2019-02-18

1138 Marked changes in diversity and relative activity of picoeukaryotes with depth in the global ocean

Giner, C. R.; Balague, V.; Pernice, M. C.; Duarte, C. M.; Gasol, J. M.; Logares, R.; Massana, R.

10.1101/552604 — microbiology — Posted on 2019-02-18

1139 Sharing information between related diseases using Bayesian joint fine mapping increases accuracy and identifies novel associations in six immune mediated diseases

Asimit, J. L.; Rainbow, D. B.; Fortune, M.; Grinberg, N. F.; Wicker, L. S.; Wallace, C.

10.1101/553560 — genomics — Posted on 2019-02-18

1140 Genetic basis of plasticity for forage quality traits in response to water deficit in a diverse germplasm panel of alfalfa

Yu, L.-X.; Boge, B.; Hu, J.; Fransen, S.; Norberg, S.

10.1101/554402 — genetics — Posted on 2019-02-18

1141 Harnessing phenotypic networks and structural equation models to improve genome-wide association analysis

Momen, M.; Campbell, M. T.; Walia, H.; Morota, G.

10.1101/553008 — genetics — Posted on 2019-02-18

1142 Does Long-Term Selection for Development Time Result in Canalization: A Test Using Drosophila melanogaster

Ghosh, S. M.; Satish, K. M.; Mohan, J.; Joshi, A.

10.1101/553123 — evolutionary biology — Posted on 2019-02-18

1143 Local-to-global signal transduction at the core of the Mn2+ sensing riboswitch

Suddala, K. C.; Price, I. R.; Janecek, M.; Kührova, P.; Dandpat, S.; Sponer, J.; Banas, P.; Ke, A.; Walter, N. G.

10.1101/553354 — biophysics — Posted on 2019-02-18

1144 Dimerization of human Rio2 kinase/ATPase locks its ATP-binding site in an apo state

Maurice, F.; Perebaskine, N.; Fribourg, S.

10.1101/553800 — biochemistry — Posted on 2019-02-18

1145 Oxytocin modulation of self-other distinction is replicable and influenced by oxytocin receptor (OXTR) genotype

Zhao, W.; Luo, R.; Sindermann, C.; Li, J.; Wei, Z.; Zhang, Y.; Liu, C.; Le, J.; Quintana, D.; Montag, C.; Becker, B.; Kendrick, K.

10.1101/552703 — neuroscience — Posted on 2019-02-18

1146 Comparative study of GenePOC GBS LB Assay and GeneXpert GBS LB Assay for the detection of Group B Streptococcus in prenatal screening samples.

Choera, T.; Jung-Hynes, B.; Chen, D.

10.1101/553487 — microbiology — Posted on 2019-02-18

1147 Persistent anti-heart autoimmunity causes cardiomyocyte damage in chronic heart failure.

Sintou, A.; el Rifai, S.; Mansfield, C.; Rothery, S.; Sanchez Alonso, J. L.; Narodden, S.; Sharma, K.; Ferraro, E.; Hasham, M. G.; Swiatlowska, P.; Harding, S. E.; Rosenthal, N.; Gorelik, J.; Sattler, S.

10.1101/542597 — immunology — Posted on 2019-02-18

1148 Temporal regulation of cell polarity via the interaction of the Ras GTPase Rsr1 and the scaffold protein Bem1

Miller, K. E.; Park, H.-O.

10.1101/554105 — cell biology — Posted on 2019-02-18

1149 Phospho-sRNA-seq reveals extracellular mRNA/lncRNA fragments as potential biomarkers in human plasma

Giraldez, M. D.; Spengler, R. M.; Etheridge, A.; Goicochea, A. J.; Tuck, M.; Choi, S. W.; Galas, D. J.; Tewari, M.

10.1101/553438 — molecular biology — Posted on 2019-02-18

1150 Hospital use of antibiotics as the main driver of infections with antibiotic-resistant bacteria - a reanalysis of recent data from the European Union

Fischer, M. M.; Bild, M.

10.1101/553537 — microbiology — Posted on 2019-02-18

1151 Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques

Sanz, J.; Maurizio, P. L.; Snyder-Mackler, N.; Simons, N. D.; Voyles, T.; Kohn, J.; Michopoulos, V.; Wilson, M.; Tung, J.; Barreiro, L. B.

10.1101/552356 — genomics — Posted on 2019-02-18

1152 Transcriptomic changes resulting from STK32B overexpression identifies pathways potentially relevant to essential tremor

Liao, C.; Sarayloo, F.; Rochefort, D.; Akcimen, F.; Diamond, S.; Laporte, A. D.; Spiegelman, D.; He, Q.; Catoire, H.; Dion, P. A.; Rouleau, G. A.

10.1101/552901 — genomics — Posted on 2019-02-18

1153 QTL and genetic analysis controlling fiber quality traits using paternal backcross population in Upland cotton

Hua, J.; Ma, L.; Su, Y.; Wang, Y.; Nie, H.; Cui, Y.; Cheng, C.; Wang, M.

10.1101/554147 — plant biology — Posted on 2019-02-18

1154 White Matter Hyperintensity Quantification in Large-Scale Clinical Acute Ischemic Stroke Cohorts - The MRI-GENIE Study

Schirmer, M. D.; Dalca, A. V.; Sridharan, R.; Giese, A.-K.; Donahue, K. L.; Nardin, M. J.; Mocking, S. J. T.; McIntosh, E. C.; Frid, P.; Wasselius, J.; Cole, J. W.; Holmegaard, L.; Jern, C.; Jimenez-Conde, J.; Lemmens, R.; Lindgren, A. G.; Meschia, J. F.; Roquer, J.; Rundek, T.; Sacco, R. L.; Schmidt, R.; Sharma, P.; Slowik, A.; Thijs, V.; Woo, D.; Vagal, A.; Xu, H.; Kittner, S. J.; McArdle, P. F.; Mitchell, B. D.; Rosand, J.; Worrall, B. B.; Wu, O.; Golland, P.; Rost, N. S.

10.1101/552844 — neuroscience — Posted on 2019-02-18

1155 PARAMO pipeline: reconstructing ancestral anatomies using ontologies and stochastic mapping

Tarasov, S.; Miko, I.; Yoder, M. J.; Uyeda, J.

10.1101/553370 — evolutionary biology — Posted on 2019-02-18

Archambeau, J.; Ruiz-Benito, P.; Ratcliffe, S.; Frejaville, T.; Changenet, A.; Munoz Castaneda, J.; Lehtonen, A.; Dahlgren, J.; Zavala, M. A.; Benito Garzon, M.

10.1101/551820 — ecology — Posted on 2019-02-18

1157 Multidimensional Profiling of Drug-Treated Cells by Imaging Mass Cytometry

Bouzekri, A.; Esch, A.; Ornatsky, O.

10.1101/549592 — cell biology — Posted on 2019-02-18

1158 Metabolic basis of brain-like electrical signalling in bacterial communities

Martinez-Corral, R.; Liu, J.; Prindle, A.; Suel, G. M.; Garcia-Ojalvo, J.

10.1101/553305 — systems biology — Posted on 2019-02-18

1159 A paper-filter system to investigate the real micro-environment circuiting plant roots

Huang, C.

10.1101/553479 — plant biology — Posted on 2019-02-18

1160 In situ structures of periplasmic flagella in Borrelia reveals conformational changes essential for flagellar rotation

Liu, J.; Chang, Y.; Moon, K.; Zhao, X.; Norris, S. J.; Motaleb, M. A.

10.1101/553289 — microbiology — Posted on 2019-02-18

1161 Intracellular AIEC LF82 relies on SOS and stringent responses to survive, multiply and tolerate antibiotics.

Demarre, G.; Prudent, V.; Schenk, H.; Rousseau, E.; Bringer, M.-A.; Barnich, N.; Tran Van Nhieu, G.; Rimsky, S.; De Monte, S.; Espeli, O.

10.1101/551226 — microbiology — Posted on 2019-02-18

1162 Gene pathogenicity prediction of Mendelian diseases via the Random Forest algorithm

He, S.; Chen, W.; Liu, H.; Li, S.; Lei, D.; Dang, X.; Chen, Y.; Zhang, X.; Zhang, J.

10.1101/553362 — genetics — Posted on 2019-02-18

1163 Age-structured vectorial capacity in a ZIKV-Ae. aegypti model system

Mayton, E. H.; Tramonte, A. R.; Christofferson, R. C.

10.1101/552125 — ecology — Posted on 2019-02-18

1164 Bolt: A new age peptide search engine for comprehensive MS/MS sequencing through vast protein databases in minutes.

Amol, P.; Ahmad, S.; Majumder, S.; Jenkins, C.; Orsburn, B.

10.1101/551622 — bioinformatics — Posted on 2019-02-18

1165 Human Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip Technology to Generate Complex Multi-Layer Tissue Models

Achberger, K.; Probst, C.; Haderspeck, J.; Bolz, S.; Rogal, J.; Chuchuy, J.; Nikolova, M.; Cora, V.; Antkowiak, L.; Haq, W.; Shen, N.; Schenke-Layland, K.; Ueffing, M.; Liebau, S.; Loskill, P.

10.1101/552158 — bioengineering — Posted on 2019-02-18

1166 Sets of Co-regulated Serum Lipids are Associated with Alzheimer Disease Pathophysiology

Barupal, D. K.; Bailli, R.; Fan, S.; Saykin, A. J.; Meikle, P. J.; Nho, K.; Arnold, M.; Fiehn, O.; Kaddurah-Daouk, R.; Alzheimer Disease Neuroimaging Initiative, ; Alzheimer Disease Metabolomics Consortium,

10.1101/550723 — neuroscience — Posted on 2019-02-18

1167 Meiotic DNA repair in the nucleolus employs a non-homologous end joining mechanism

Sims, J.; Copenhaver, G. P.; Schloegelhofer, P.

10.1101/553529 — molecular biology — Posted on 2019-02-18

1168 H2A.Z-dependent and -independent recruitment of metabolic enzymes to chromatin required for histone modifications

Choi, S.; Jeon, Y. H.; Yang, Z.; He, M.; Shin, H.; Pfleger, J.; Sayed, D.; Astrof, S.; Abdellatif, M.

10.1101/553297 — molecular biology — Posted on 2019-02-18

1169 Traces of past transposable element presence in Brassicaceae genome dark matter

Baud, A.; Wan, M.; Nouaud, D.; Anxolabehere, D.; Quesneville, H.

10.1101/547877 — genomics — Posted on 2019-02-18

1170 Haplotype-Based Noninvasive Prenatal Diagnosis for Duchenne Muscular Dystrophy: A pilot study in South China

Chen, M.; Chen, C.; Li, Y.; Yuan, Y.; Lai, Z.; Guo, F.; Wang, Y.; Huang, X.; Li, S.; Wu, R.; Peng, Z.; Sun, J.; Chen, D.

10.1101/551200 — genetics — Posted on 2019-02-18

1171 Micro-indentation and optical coherence tomography for the mechanical characterization of embryos: Experimental setup and measurements on fixed chicken embryos.

Marrese, M.; Antonovaite, N.; Nelemans, B. K. A.; Smit, T. H.; Iannuzzi, D.

10.1101/553693 — developmental biology — Posted on 2019-02-18

1172 Gene expression noise randomizes the adaptive response to DNA alkylation damage in E. coli

Uphoff, S.

10.1101/551911 — biophysics — Posted on 2019-02-18

1173 Dynamic clustering regulates activity of mechanosensitive membrane channels

Paraschiv, A.; Hegde, S.; Ganti, R.; Pilizota, T.; Saric, A.

10.1101/553248 — biophysics — Posted on 2019-02-18

1174 Comparison of SVM and Spectral Embedding in Promoter Biobricks' Categorizing and Clustering

Zou, S.

10.1101/553412 — bioinformatics — Posted on 2019-02-18

1175 Neural System Identification with Cortical Information Flow

Ambrogioni, L.; Seeliger, K.; Guclu, U.; van Gerven, M.

10.1101/553255 — neuroscience — Posted on 2019-02-18

1176 The fog of genetics: Known unknowns and unknown unknowns in the genetics of complex traits and diseases

de Magalhaes, J. P.; Wang, J.

10.1101/553685 — genetics — Posted on 2019-02-18

1177 A quantitative tri-fluorescent yeast two-hybrid system: from flow cytometry to in-cellula affinities

Cluet, D.; Amri, I.; Vergier, B.; Leault, J.; Grosjean, C.; Calabresi, D.; Spichty, M.

10.1101/553636 — biochemistry — Posted on 2019-02-18

1178 Experimental evidence that belowground competition can influence the evolution of root traits in two closely related morning glory species

Colom, S. M.; Baucom, R. S.

10.1101/553115 — evolutionary biology — Posted on 2019-02-18

1179 Cancer gene therapy by NF-κB-activated cancer cell-specific expression of CRISPR/Cas9 targeting to telomere

Dai, W.; Wu, J.; Wang, D.; Wang, J.

10.1101/553099 — cancer biology — Posted on 2019-02-18

1180 Motor cortex signals corresponding to the two arms are shared across hemispheres, mixed among neurons, yet partitioned within the population response

Ames, K. C.; Churchland, M. M.

10.1101/552257 — neuroscience — Posted on 2019-02-18

1181 Comparison of classification methods for tissue outcome after ischemic stroke

Tozlu, C.; Ozenne, B.; Cho, T.-H.; Nighoghossian, N.; Mikkelsen, I. K.; Derex, L.; Hermier, M.; Pedraza, S.; Fiehler, J.; Ostergaard, L.; Berthezene, Y.; Baron, J. C.; Maucort-Boulch, D.

10.1101/551903 — neuroscience — Posted on 2019-02-18

1182 Short-Term Plasticity Following Motor Sequence Learning Revealed by Diffusion MRI

Tavor, I.; Botvinik-Nezer, R.; Bernstein-Eliav, M.; Tsarfaty, G.; Assaf, Y.

10.1101/553628 — neuroscience — Posted on 2019-02-18

1183 Trait-based life-history strategies explain succession scenario for complex bacterial communities under varying disturbance

Santillan, E.; Seshan, H.; Constancias, F.; Wuertz, S.

10.1101/546416 — microbiology — Posted on 2019-02-18

1184 Calcium-dependent protein kinase 5 links calcium-signaling with SARD1-dependent immune memory in systemic acquired resistance

Guerra, T.; Schilling, S.; Sylvester, F.-P.; Conrads, B.; Romeis, T.

10.1101/553750 — plant biology — Posted on 2019-02-18

1185 I believe, therefore I am: Effects of self-control beliefs on behavioral and electrophysiological markers of inhibitory and emotional attention control

Vanlessen, N.; Rigoni, D.; Schettino, A.; Brass, M.

10.1101/552570 — neuroscience — Posted on 2019-02-18

1186 A network supporting social influences in human decision-making

Zhang, L.; Glascher, J. P.

10.1101/551614 — neuroscience — Posted on 2019-02-18

1187 Auditory perceptual history is communicated through alpha oscillations

Ho, H. T.; Leung, J.; Burr, D. C.; Alais, D.; Morrone, M. C.

10.1101/553222 — neuroscience — Posted on 2019-02-18

1188 Evaluating Complexity of Fetal MEG Signals: A Comparison of Different Metrics and Their Applicability

Moser, J.; Bensaid, S.; Kroupi, E.; Schleger, F.; Wendling, F.; Ruffini, G.; Preissl, H.

10.1101/540278 — neuroscience — Posted on 2019-02-18

1189 Skin transcriptome reveals the Periodic changes in genes underlying hair follicle cycling in Cashmere

Liu, Z.; Yang, F.; Zhao, M.; Mu, Q.; Che, T.; Li, J.; Zhao, Y.

10.1101/554030 — genomics — Posted on 2019-02-18

1190 The Juvenile Idiopathic Arthritis (JIA) Susceptibility Locus, IL2RA, Includes An Intronic Enhancer That Is Attenuated By JIA-Associated Genetic Variants

Jarvis, J. N.; Jiang, K.; Park, Y.; Tarbell, E.; Liu, T.

10.1101/554006 — genetics — Posted on 2019-02-18

1191 The locomotor and predatory habits of unenlagiines (Theropoda, Paraves): inferences based on morphometric studies and comparisons with Laurasian dromaeosaurids

Gianechini, F. A.; Ercoli, M. D.; Diaz-Martinez, I.

10.1101/553891 — paleontology — Posted on 2019-02-18

1192 2-Cl-C.OXT-A Stimulates Contraction through the Suppression of Phosphodiesterase Activity in Human Induced Pluripotent Stem Cell-derived Cardiac Organoids

Kitsuka, T.; Itoh, M.; Amamoto, S.; Arai, K.-i.; Oyama, J.; Node, K.; Toda, S.; Morita, S.; Nishida, T.; Nakayama, K.

10.1101/553826 — pharmacology and toxicology — Posted on 2019-02-18

1193 RecV recombinase system for spatiotemporally controlled light-inducible genomic modifications.

Cetin, A. H.; Yao, S.; Ouellette, B.; Balaram, P.; Zhou, T.; Mortrud, M.; Chatterjee, S.; Wang, Y.; Daigle, T. L.; Tasic, B.; Kuang, X.; Gong, H.; Luo, Q.; Zeng, S.; Kahan, A.; Gradinaru, V.; Zeng, H.

10.1101/553271 — neuroscience — Posted on 2019-02-18

1194 Serologic evidence of seasonal influenza A and B viruses in HIV patients on combined antiretroviral therapy in Lagos, Nigeria

Anjorin, A. A.; Adepoju, B. A.

10.1101/553958 — microbiology — Posted on 2019-02-18

1195 Transcriptional Blood Signatures for Active and Amphotericin B Treated Visceral Leishmaniasis in India

Blackwell, J. M.; Fakiola, M.; Singh, O.-P.; Syn, G.; Singh, T.; Singh, B.; Chakravarty, J.; Sundar, S.

10.1101/554022 — genomics — Posted on 2019-02-18

1196 The yeast Art1 arrestin domain contains disordered insertions that regulate its localization and activity

Baile, M. G.; Guiney, E. L.; Sanford, E. J.; MacGurn, J. A.; Smolka, M. B.; Emr, S. D.

10.1101/553677 — cell biology — Posted on 2019-02-18

1197 Application of seaweed organic components increases tolerance to Fe deficiency in tomato plants

Carrasco-Gil, S.; Allende-Montalban, R.; Hernandez-Apaolaza, L.; Lucena, J. J.

10.1101/553917 — plant biology — Posted on 2019-02-18

1198 Precise removal of Calm1 long 3′ UTR isoform by CRISPR-Cas9 genome editing impairs dorsal root ganglion development in mice.

Gruner, H. N.; Bae, B.; Lynch, M.; Oliver, D.; So, K.; Mastick, G. S.; Yan, W.; Miura, P.

10.1101/553990 — genetics — Posted on 2019-02-18

1199 Future sea-level rise drives rocky intertidal habitat loss and benthic community change

Kaplanis, N.; Edwards, C. B.; Eynaud, Y.; Smith, J. E.

10.1101/553933 — ecology — Posted on 2019-02-18

1200 The down regulation of megalin/LRP2 by transforming growth factor beta (TGF-ss1) is mediated by the SMAD2/3 signalling pathway

Cabezas, F.; Farfan, P.; Marzolo, M.-P.

10.1101/553974 — cell biology — Posted on 2019-02-18

1201 Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)

Henley, J.; Lee, L.; Wilkinson, K.; Seager, R.

10.1101/553859 — cell biology — Posted on 2019-02-18

1202 Modeling and Visualization of Rice Root Based on Morphological Parameters

Yang, L.; Shao, P.

10.1101/553925 — bioinformatics — Posted on 2019-02-18

1203 Optimization of the cultivation conditions of indigenous wild yeasts and evaluation of their leavening capacity: Isolated from fermented foods and beverages.

Gebreslassie, E. B.; Tefera, A. T.; Muleta, D.; Fantaye, S. k.; Wessel, G. M.

10.1101/553818 — microbiology — Posted on 2019-02-18

1204 Spatiotemporal analysis of human rabies exposure in Colombia during ten years: A challenge for implementing social inclusion in its surveillance and prevention

Arias Caicedo, M. R.; Arias Caicedo, C. A.; Andrade Monteiro, E.; Abel, I.; de Arruda Xavier, D.

10.1101/553909 — epidemiology — Posted on 2019-02-18

1205 Tbx1 interacts genetically with Vegfr3 to regulate cardiac lymphangiogenesis in mice

Martucciello, S.; Turturo, M. G.; Cioffi, S.; Chen, L.; Baldini, A.; Illingworth, E. A.

10.1101/553578 — developmental biology — Posted on 2019-02-18

1206 The international sinonasal microbiome study (ISMS): a multi-centre, multi-national collaboration characterising the microbial ecology of the sinonasal cavity

Paramasivan, S.; Bassiouni, A.; Shiffer, A.; Dillon, M. R.; Cope, E. K.; Cooksley, C.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/548743 — microbiology — Posted on 2019-02-17

1207 Microbiotyping the sinonasal microbiome

Bassiouni, A.; Paramasivan, S.; Shiffer, A.; Dillon, M. R.; Cope, E. K.; Cooksley, C.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/549311 — microbiology — Posted on 2019-02-17

1208 A large proportion of poor birth outcomes among Aboriginal Western Australians are attributable to smoking, alcohol and substance misuse, and assault

Gibberd, A. J.; Simpson, J. M.; Jones, J.; Williams, R.; Stanley, F.; Eades, S. J.

10.1101/553065 — epidemiology — Posted on 2019-02-17

1209 Collateral development and arteriogenesis in hindlimbs of domestic swine after ligation of arterial inflow

Gao, Y.; Patel, N. S.; Aravind, S.; Fugelstad, M.; Casale, G.; Pipinos, I. I.; Carlson, M. A.

10.1101/491928 — physiology — Posted on 2019-02-17

1210 Detection of classic and cryptic Strongyloides genotypes by deep amplicon sequencing: A preliminary survey of dog and human specimens collected from remote Australian communities

Beknazarova, M.; Barratt, J. L. N.; Bradbury, R. S.; Lane, M.; Whiley, H.; Ross, K.

10.1101/549535 — zoology — Posted on 2019-02-17

1211 ELECTOR: Evaluator for long reads correction methods

Marchet, C.; Morisse, P.; Lecompte, L.; Lefebvre, A.; Lecroq, T.; Peterlongo, P.; limasset, a.

10.1101/512889 — bioinformatics — Posted on 2019-02-17

1212 Extracellular mycobacterial DNA drives disease progression by triggering Caspase-11-dependent pyroptosis of infected macrophages

Varela, M.; van der Vaart, M.; Groenewoud, A.; Meijer, A. H.

10.1101/514125 — immunology — Posted on 2019-02-17

1213 Attacked from above and below, new observations of cooperative and solitary predators on roosting cave bats

Tanalgo, K. C.; Waldien, D. L.; Monfort, N.; Hughes, A. C.

10.1101/550582 — animal behavior and cognition — Posted on 2019-02-17

1214 SwiftOrtho: a Fast, Memory-Efficient, Multiple Genome Orthology Classifier

Hu, X.; Friedberg, I.

10.1101/543223 — bioinformatics — Posted on 2019-02-17

1215 Applications of community detection algorithms to large biological datasets

Kanter, I.; Yaari, G.; Kalisky, T.

10.1101/547570 — bioinformatics — Posted on 2019-02-17

1216 SorCS1-mediated Sorting of Neurexin in Dendrites Maintains Presynaptic Function

Ribeiro, L. F.; Verpoort, B.; Nys, J.; Vennekens, K. M.; Wierda, K. D.; de Wit, J.

10.1101/552695 — neuroscience — Posted on 2019-02-17

1217 Whole plant community transplants across climates reveal structural community stability due to large shifts in species assemblage

Tomiolo, S.; Bilton, M. C.; Tielboerger, K.

10.1101/475046 — ecology — Posted on 2019-02-17

1218 Robo2 regulates synaptic oxytocin content by affecting actin state

Anbalagan, S.; Blechman, J.; Gliksberg, M.; Rotkopf, R.; Dadosh, T.; Levkowitz, G.

10.1101/553198 — developmental biology — Posted on 2019-02-17

1219 The Human Default Consciousness and its Disruption: Insights from an EEG Study of Buddhist Jhana Meditation

Dennison, P.

10.1101/407544 — neuroscience — Posted on 2019-02-17

1220 Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development

Haerlingen, B.; Opitz, R.; Vandernoot, I.; Trubiroha, A.; Gillotay, P.; Giusti, N.; Costagliola, S.

10.1101/551861 — developmental biology — Posted on 2019-02-17

1221 Generalized Rayleigh-Plesset Theory for Cell Size Maintenance in Viruses and Bacteria

Malmi-Kakkada, A.; Thirumalai, D.

10.1101/552778 — cell biology — Posted on 2019-02-17

1222 In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

Munro, S.; Gillingham, A. K.; Bertram, J.; Begum, F.

10.1101/553206 — cell biology — Posted on 2019-02-17

1223 Evolutionary dynamics of phage resistance in bacterial biofilms

Simmons, M.; Bond, M. C.; Drescher, K.; Bucci, V.; Nadell, C. D.

10.1101/552265 — microbiology — Posted on 2019-02-17

1224 Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole Genome Sequencing Studies

Li, Z.; Li, X.; Liu, Y.; Shen, J.; Chen, H.; Zhou, H.; Morrison, A. C.; Boerwinkle, E.; Lin, X.

10.1101/552950 — genetics — Posted on 2019-02-17

1225 A test for Hardy-Weinberg equilibrium on the X chromosome for sex-biased admixed populations

Backenroth, D.; Carmi, S.

10.1101/552794 — genetics — Posted on 2019-02-17

1226 Empirical measures of mutational effects define neutral models of regulatory evolution in Saccharomyces cerevisiae

Hodgins-Davis, A.; Duveau, F.; Walker, E. A.; Wittkopp, P. J.

10.1101/551804 — evolutionary biology — Posted on 2019-02-17

1227 Cell type specific transcriptional reprogramming of maize leaves during Ustilago maydis induced tumor formation

Villajuana-Bonequi, M.; Matei, A.; Ernst, C.; Hallab, A.; Usadel, B.; Doehlemann, G.

10.1101/552562 — plant biology — Posted on 2019-02-17

1228 Infection triggers tumor regression through activation of innate immunity in Drosophila

Jacqueline, C.; Parvy, J.-P.; Faugere, D.; Renaud, F.; Misse, D.; Thomas, F.; Roche, B.

10.1101/552869 — immunology — Posted on 2019-02-17

1229 DRAFT - Robotic automation of production and the recovery of cell spheroids

Langer, K.; Jonsson, H.

10.1101/552687 — bioengineering — Posted on 2019-02-17

1230 Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation

Sasani, T. A.; Pedersen, B. S.; Gao, Z.; Baird, L.; Przeworski, M.; Jorde, L. B.; Quinlan, A. R.

10.1101/552117 — genetics — Posted on 2019-02-17

1231 Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis

Ryan, S. M.; Almassey, M.; Burch, A. M.; Ngo, G.; Barbee, S.; Mortimer, N. T.; Sanyal, S.; Vrailas-Mortimer, A.

10.1101/552729 — genetics — Posted on 2019-02-17

1232 Phytochemical evaluation, Embryotoxicity and Teratogenic effects of Curcuma longa extract in Zebrafish (Danio rerio).

Alafiatayo, D. A. A.; Song, L. K.; Ahmad, S.; Mahmood, M.; Shaharuddin, N. A.

10.1101/551044 — developmental biology — Posted on 2019-02-17

1233 Ancestral and neo-sex chromosomes contribute to population divergence in a dioecious plant

Beaudry, F.; Barrett, S. C. H.; Wright, S. I.

10.1101/550962 — plant biology — Posted on 2019-02-17

1234 Quantifying the dynamics of hematopoiesis by in vivo IdU pulse-chase, mass cytometry and mathematical modeling

Erez, A.; Mukherjee, R.; Day, A.; Mehta, P.; Altan-Bonnet, G.

10.1101/552489 — immunology — Posted on 2019-02-17

1235 A Molecular Tension Sensor for N-Cadherin Reveals Distinct Forms of Mechanosensitive Adhesion Assembly in Adherens and Synaptic Junctions

Puranam, I.; Urs, A.; Kirk, B.; Newell-Litwa, K.; Hoffman, B.

10.1101/552802 — bioengineering — Posted on 2019-02-17

1236 Modeling ribosome dwell times and relationships with tRNA loading and codon usage in mammals

Gobet, C.; Weger, B.; Marquis, J.; Martin, E.; Gachon, F.; Naef, F.

10.1101/551838 — systems biology — Posted on 2019-02-17

1237 Stereotactic electroencephalography in humans reveals multisensory signal in early visual and auditory cortices

Ferraro, S.; Van Ackeren, M. J.; Mai, R.; Tassi, L.; Cardinale, F.; Nigri, A.; Bruzzone, M. G.; D'Incerti, L.; Hartmann, T.; Weisz, N.; Collignon, O.

10.1101/549733 — neuroscience — Posted on 2019-02-17

1238 Bdnf promoter IV-expressing cells in the hippocampus modulate fear expression and hippocampal-prefrontal synchrony in mice

Hallock, H. L.; Quillian, H. M.; Mai, Y.; Maynard, K. R.; Hill, J. L.; Martinowich, K.

10.1101/552646 — neuroscience — Posted on 2019-02-17

1239 Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13

Hou, J.; Wu, T.; Cao, R.; Cheng, J.

10.1101/552422 — bioinformatics — Posted on 2019-02-17

1240 Single-cell activity in human STG during perception of phonemes is organized according to manner of articulation

Yair, L.; Ossmy, O.; Friedmann, N.; Mukamel, R.; Fried, I.

10.1101/552315 — neuroscience — Posted on 2019-02-17

1241 SEDS-bPBP pairs direct lateral and septal peptidoglycan synthesis in Staphylococcus aureus

Reichmann, N. T.; Tavares, A. C.; Saraiva, B. M.; Jousselin, A.; Reed, P.; Pereira, A. R.; Monteiro, J. M.; VanNieuwenhze, M. S.; Fernandes, F.; Pinho, M. G.

10.1101/552034 — microbiology — Posted on 2019-02-17

1242 Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing

Daniszewski, M.; Anderson, M.; Shi, Q.; Shi, L.; Liu, P.; Jiang, F.; Zhang, W.; Wing, K.; Daniszewski, M.; Lukowski, S.; Hung, S.; Nguyen, Q.; Fink, L.; Beckhouse, A.; Jiang, H.; Pebay, A.; Hewitt, A.; Powell, J.

10.1101/552588 — genomics — Posted on 2019-02-17

1243 Pathogen to commensal: longitudinal within-host population dynamics, evolution, and adaptation during a chronic >16-year Burkholderia pseudomallei infection

Pearson, T.; Sahl, J.; Hepp, C. M.; Handady, K.; Hornstra, H.; Vazquez, A. J.; Settles, E.; Mayo, M.; Kaestli, M.; Williamson, C. H. D.; Price, E. P.; Sarovich, D. S.; Cook, J. M.; Wolken, S. R.; Bowen, R. A.; Tuanyok, A.; Foster, J. T.; Drees, K. P.; Kidd, T. J.; Bell, S. C.; Currie, B. J.; Keim, P.

10.1101/552109 — evolutionary biology — Posted on 2019-02-17

1244 In Silico Analysis and Modeling of Novel Pathogenic Single Nucleotide Polymorphisms (SNPs) in Human CD40LG Gene

Abdelmoneim, A. H.; Mustafa, M. I.; Mahmoud, T. A.; Murshed, N. S.; Hassan, M. A.

10.1101/552596 — bioinformatics — Posted on 2019-02-17

1245 Genetic variation influences pluripotent ground state stability in mouse embryonic stem cells through a hierarchy of molecular phenotypes

Skelly, D. A.; Czechanski, A.; Byers, C.; Aydin, S.; Spruce, C.; Olivier, C.; Choi, K.; Gatti, D. M.; Raghupathy, N. M.; Stanton, A.; Vincent, M.; Dion, S.; Greenstein, I.; Pankratz, M.; Porter, D. K.; Martin, W.; Qin, W.; Harrill, A. H.; Choi, T.; Churchill, G. A.; Munger, S. C.; Baker, C. L.; Reinholdt, L. G.

10.1101/552059 — genomics — Posted on 2019-02-17

1246 Arginine culture generates triacylglycerol by triggering nitrogen starvation responses during robust growth in Chlamydomonas

Munz, J.; Xiong, Y.; Kim, J. Y. H.; Sung, Y. J.; Seo, S.; Hong, R. H.; Kariyawasam, T.; Shelley, N.; Lee, J.; Sim, S. J.; Jin, E.; Lee, J.-H.

10.1101/416594 — plant biology — Posted on 2019-02-16

1247 Collateral development and arteriogenesis in hindlimbs of domestic swine after ligation of arterial inflow

Gao, Y.; Patel, N. S.; Aravind, S.; Fugelstad, M.; Casale, G.; Pipinos, I. I.; Carlson, M. A.

10.1101/491928 — physiology — Posted on 2019-02-16

1248 Brucella EipB is a periplasmic β-spiral protein required for envelope stress resistance and infection

Herrou, J.; Willett, J.; Fiebig, A.; Czyz, D.; Cheng, J.; Ultee, E.; Briegel, A.; Bigelow, L.; Babnigg, G.; Kim, Y.; Crosson, S.

10.1101/551135 — microbiology — Posted on 2019-02-16

1249 Extraction-free direct PCR from dried serum spots permits HBV genotyping and RAS identification by Sanger and minION sequencing

Astbury, S.; Soares, M. M. D. C. N.; Peprah, E.; King, B. J.; Jardim, A. C. G.; Shimizu, J. F.; Jalal, P. J.; Saeed, C. H.; Sabeer, F. T.; Irving, W. L.; Tarr, A. W.; McClure, C. P.

10.1101/552539 — microbiology — Posted on 2019-02-16

1250 Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction

Perfitt, T. L.; Wang, X.; Stephenson, J. R.; Nakagawa, T.; Colbran, R. J.

10.1101/551648 — neuroscience — Posted on 2019-02-16

1251 Brucella EipB is periplasmic β-spiral protein required for envelope stress resistance and infection

Herrou, J.; Willett, J.; Fiebig, A.; Czyz, D.; Cheng, J.; Ultee, E.; Briegel, A.; Bigelow, L.; Babnigg, G.; Kim, Y.; Crosson, S.

10.1101/551135 — microbiology — Posted on 2019-02-16

1252 Manatee genomics supports a special conservation area in the Guianas coastline under the influence of the Amazon River plume

Vilaca, S. T.; Lima, C. S.; Mazzoni, C. J.; Santos, F. R.; de Thoisy, B.

10.1101/552919 — genomics — Posted on 2019-02-16

1253 De novo diploid genome assembly for genome-wide structural variant detection

Zhang, L.; Zhou, X.; weng, z.; Sidow, A.

10.1101/552430 — genomics — Posted on 2019-02-16

1254 SquiggleKit: A toolkit for manipulating nanopore signal data

Ferguson, J. M.; Smith, M.

10.1101/549741 — bioinformatics — Posted on 2019-02-16

1255 High-Fidelity Nanopore Sequencing of Ultra-Short DNA Sequences

Wilson, B. D.; Eisenstein, M.; Soh, H. T.

10.1101/552224 — bioengineering — Posted on 2019-02-16

1256 A \"Dirty\" Footprint: Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests

Demetrio, W. C.; Conrado, A. C.; Acioli, A.; Ferreira, A. C.; Bartz, M. L.; James, S. W.; da Silva, E.; Maia, L. S.; Martins, G. C.; Macedo, R. S.; Stanton, D. W. G.; Lavelle, P.; Velasquez, E.; Zangerle, A.; Tapia-Coral, S.; Barbosa, R.; Muniz, A. W.; Santos, A.; Ferreira, T.; Segalla, R. F.; Decaens, T.; PenaVenegas, C. P.; Nadolny, H. S.; Maia, C. S.; Pasini, A.; Motta, A. F.; Taube Junior, P. S.; Silva, T. A.; Rebellato, L.; Oliveira Junior, R. C.; Neves, E. G.; Pinto Lima, H.; Feitosa, R.; Vidal Torrado, P.; McKey, D.; Clement, C. R.; Shock, M. P.; Teixeira, W. G.; Carlos V. Motta, A.; de

10.1101/552364 — zoology — Posted on 2019-02-16

1257 Feed-forward regulation adaptively evolves via dynamics rather than topology when there is intrinsic noise

Xiong, K.; Lancaster, A. K.; Siegal, M. L.; Masel, J.

10.1101/393884 — systems biology — Posted on 2019-02-16

1258 A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry

Jackson, P. E. H.; Huang, J.; Sharma, M.; Rasmussen, S. K.; Hammarskjold, M.-L.; Rekosh, D.

10.1101/551846 — molecular biology — Posted on 2019-02-16

1259 Variation in genome content and predatory phenotypes between Bdellovibrio sp. NC01 isolated from soil and B. bacteriovorus type strain HD100

Williams, L. E.; Cullen, N.; DeGiorgis, J. A.; Martinez, K. J.; Mellone, J.; Oser, M.

10.1101/551937 — microbiology — Posted on 2019-02-16

1260 Semi-quantitative characterisation of mixed pollen samples using MinION sequencing and Reverse Metagenomics (RevMet)

Peel, N.; Dicks, L.; Clark, M. D.; Heavens, D.; Percival-Alwyn, L.; Cooper, C.; Davies, R. G.; Leggett, R. M.; Yu, D. W.

10.1101/551960 — ecology — Posted on 2019-02-16

1261 Ouabain enhances cell-cell adhesion mediated by β1-subunits of the Na+,K+-ATPase in CHO fibroblasts.

Vilchis-Nestor, C. A.; Roldan, M. L.; Padilla-Benavides, T.; Shoshani, L.

10.1101/552497 — cell biology — Posted on 2019-02-16

1262 Probabilistic associative learning suffices for learning the temporal structure of multiple sequences

Martinez, R. H.; Lansner, A.; Herman, P.

10.1101/545871 — neuroscience — Posted on 2019-02-16

1263 Rare Microbial Taxa Emerge When Communities Collide: Freshwater and Marine Microbiome Responses to Experimental Seawater Intrusion

Rocca, J. D.; Simonin, M.; Wright, J.; Washburne, A.; Bernhardt, E. S.

10.1101/550756 — ecology — Posted on 2019-02-16

1264 Identification of genes with enriched expression in early developing mouse cone photoreceptors

Buenaventura, D. F.; Corseri, A.; Emerson, M. M.

10.1101/538611 — developmental biology — Posted on 2019-02-16

1265 F-BAR Cdc15 Promotes Gef1-mediated Cdc42 Activation During Cytokinesis and Cell Polarization in S. pombe

Hercyk, B. S.; Das, M. E.

10.1101/552927 — cell biology — Posted on 2019-02-16

1266 A Teensy microcontroller-based interface for optical imaging camera control during behavioral experiments

Romano, M.; Bucklin, M.; Mehrotra, D. R.; Kessel, R.; Gritton, H.; Han, X.

10.1101/475350 — neuroscience — Posted on 2019-02-16

1267 Aβ-Positivity Predicts Cognitive Decline but Cognition Also Predicts Progression to Aβ-Positivity

Elman, J. A.; Panizzon, M. S.; Franz, C. E.; Gustavson, D. E.; Sanderson, M. E.; Lyons, M. J.; Kremen, W. S.

10.1101/523787 — neuroscience — Posted on 2019-02-16

1268 Evolutionary significance of the structural segments trailing beta strand 5 and alpha helix 10 in the design of catalytically active NAL superfamily

Prem Kumar, M. K.; Manoharan, P.

10.1101/505230 — evolutionary biology — Posted on 2019-02-16

1269 Reward-driven changes in striatal pathway competition shape evidence evaluation in decision-making

Dunovan, K.; Vich, C.; Clapp, M.; Verstynen, T.; Rubin, J.

10.1101/418756 — neuroscience — Posted on 2019-02-16

1270 Deep learning facilitates rapid classification of human and veterinary clinical narratives

Lopez Pineda, A.; Bear Don't Walk, O. J.; Venkataraman, G. R.; Zehnder, A. M.; Ayyar, S.; Page, R. L.; Bustamante, C. D.; Rivas, M. A.

10.1101/429720 — epidemiology — Posted on 2019-02-16

1271 An Interscholastic Network to Generate LexA Enhancer Trap Lines in Drosophila

Kockel, L.; Griffin, C.; Ahmed, Y.; Fidelak, L.; Rajan, A.; Gould, E. P.; Haigney, M.; Ralston, B.; Tercek, R. J.; Galligani, L.; Rao, S.; Huq, L.; Bhargava, H. K.; Dooner, A. C.; Lemmerman, E. G.; Malusa, R. F.; Nguyen, T. H.; Chung, J. S.; Gregory, S. M.; Kuwana, K. M.; Regenold, J. T.; Wei, A.; Ashton, J.; Dickinson, P.; Kim, S.; Martel, K.; Cai, C.; Chen, C.; Price, S.; Qiao, J.; Shepley, D.; Zhang, J.; Chalasani, M.; Nguyen, K.; Aalto, A.; Kim, B.; Tazawa-Goodchild, E.; Sherwood, A.; Rahman, A.; Wu, S. Y. C.; Lotzkar, J.; Michaels, S.; Aristotle, H.; Clark, A.; Gasper, G.; Xiang, E.; Schl

10.1101/552513 — genetics — Posted on 2019-02-16

1272 Spatiotemporal prediction of wildfire extremes with Bayesian finite sample maxima

Joseph, M. B.; Rossi, M. W.; Mietkiewicz, N. P.; Mahood, A. L.; Cattau, M. E.; St. Denis, L. A.; Nagy, R. C.; Iglesias, V.; Abatzoglou, J. T.; Balch, J. K.

10.1101/384115 — ecology — Posted on 2019-02-16

1273 Polar relaxation by dynein-mediated removal of cortical myosin II

Chapa-y-Lazo, B.; Hamanaka, M.; Wray, A.; Balasubramanian, M. K.; Mishima, M.

10.1101/552372 — cell biology — Posted on 2019-02-16

1274 Interneuron functional diversity in the mouse accessory olfactory bulb

Maksimova, M. A.; Cansler, H. L.; Zuk, K. E.; Torres, J. M.; Roberts, D. J.; Meeks, J. P.

10.1101/552463 — neuroscience — Posted on 2019-02-16

1275 A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans

Saraiva, L. R.; Riveros-Mckay Aguilera, F. R.; Mezzavilla, M.; Abou-Moussa, E. H.; Arayata, C. J.; Trimmer, C.; Ibarra-Soria, X.; Khan, M.; van Gerven, L.; Jorissen, M.; Gibbs, M.; O'Flynn, C.; McGrane, S.; Mombaerts, P.; Marioni, J. R.; Mainland, J.; Logan, D. W.

10.1101/552232 — neuroscience — Posted on 2019-02-16

1276 Clueless forms dynamic, insulin-responsive bliss particles sensitive to stress

Sheard, K. M.; Thibault-Sennett, S. A.; Sen, A.; Shewmaker, F.; Cox, R.

10.1101/552455 — cell biology — Posted on 2019-02-16

1277 PROGRESSION OF AUTOANTIBODIES ANTI-GAD AND ANTI-IA2 IN TYPE 1A DIABETICS AGED OF 5 TO 21 YEARS IN CÔTE D'IVOIRE

Trebissou, A. F. J.; Yapo-Crezoit, C. C. A.; Sibailly, P.; Sanogo, M.; Ankotche, A.; Kouassi, D.; Kouassi, M. T.; Masmoudi, H.; Yapo, A. F.

10.1101/551473 — immunology — Posted on 2019-02-16

1278 Cold Vacuum Extracts of Double Cherry Blossom (Gosen-Sakura) Leaves Show Antitumor Activity

Rakwal, R.; Shibato, J.; Takenoya, F.; Hirabayashi, T.; Kimura, A.; Iwasaki, Y.; Toyota, Y.; Hori, M.; Tamogami, S.; Shioda, S.

10.1101/551424 — plant biology — Posted on 2019-02-16

1279 Honey bees, Apis mellifera, are important pollinators of the highbush blueberry variety Ventura despite the inability to sonicate

Martin, K.; Anderson, B.; Minnaar, C.; de Jager, M.

10.1101/551523 — plant biology — Posted on 2019-02-16

1280 The value of non-motor features and genetic variants of Parkinson's disease for clustering Lewy body diseases

Lucas-Jimenez, O.; Diez, I.; Ojeda, N.; Ibarretxe-Bilbao, N.; Pena, J.; Tijero, B.; Galdos, M.; Murueta-Goyena, A.; Del Pino, R.; Acera, M.; Gomez-Esteban, J. C.; Gabilondo, I.

10.1101/551507 — neuroscience — Posted on 2019-02-16

1281 Tuning network dynamics from criticality to the chaotic balanced state

Li, J.; Shew, W.

10.1101/551457 — neuroscience — Posted on 2019-02-16

1282 Differences in word learning: bilingualism or linguistic experience?

borragan, m.; de Bruin, A.; Havas, V.; de Diego Balaguer, R.; Dimitrova Vulchanova, M.; Vulchanov, V.; Dunabeitia, J. A.

10.1101/551408 — neuroscience — Posted on 2019-02-16

1283 Flower-like patterns in multi-species biofilms

Xiong, L.; Cao, Y.; Cooper, R.; Rappel, W.-J.; Hasty, J.; Tsimring, L.

10.1101/550996 — microbiology — Posted on 2019-02-16

1284 Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment

Leshchiner, I.; Livitz, D.; Gainor, J. F.; Rosebrock, D.; Spiro, O.; Martinez, A.; Mroz, E.; Lin, J. J.; Stewart, C.; Kim, J.; Elagina, L.; Bozic, I.; Mino-Kenudson, M.; Rooney, M.; Ou, S.-H. I.; Wu, C. J.; Rocco, J. W.; Engelman, J. A.; Shaw, A. T.; Getz, G.

10.1101/508127 — bioinformatics — Posted on 2019-02-16

1285 Genetic variation in the odorant receptor gene OR4 and bit habits in natural populations of Aedes aegypti from Antioquia department, Colombia.

Pino Bustamante, J. S.

10.1101/552182 — molecular biology — Posted on 2019-02-15

1286 An assay to measure the activity of RNA elements and proteins that promote the expression of mRNA with retained introns

Jackson, P. E. H.; Huang, J.; Sharma, M.; Rasmussen, S. K.; Hammarskjold, M.-L.; Rekosh, D.

10.1101/551846 — molecular biology — Posted on 2019-02-15

1287 Randomized lasso associates freshwater lake-system specific bacterial taxa with heterotrophic production through flow cytometry

Rubbens, P.; Schmidt, M. L.; Props, R.; Biddanda, B. A.; Boon, N.; Waegeman, W.; Denef, V. J.

10.1101/392852 — ecology — Posted on 2019-02-16

1288 PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells

Mallol, A.; Guirola, M.; Payer, B.

10.1101/551895 — developmental biology — Posted on 2019-02-16

1289 High-throughput single-particle tracking reveals nested membrane nanodomain organization that dictates Ras diffusion and trafficking

Lee, Y.; Phelps, C.; Huang, T.; Mostofian, B.; Wu, L.; Zhang, Y.; Chang, Y. H.; Stork, P. J. S.; Gray, J. W.; Zuckerman, D. M.; Nan, X.

10.1101/552075 — biophysics — Posted on 2019-02-15

1290 STING polymer structure reveals mechanisms for activation, hyperactivation, and inhibition

Ergun, S. L.; Fernandez, D.; Weiss, T. M.; Li, L.

10.1101/552166 — biochemistry — Posted on 2019-02-15

1291 The structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin

Flydal, M. I.; Alcorlo-Pages, M.; Johannessen, F. G.; Martinez-Caballero, S.; Skjaerven, L.; Fernandez-Leiro, R.; Martinez, A.; Hermoso, J. A.

10.1101/552281 — biochemistry — Posted on 2019-02-15

1292 Molecular chaperones accelerate the evolution of their protein clients in yeast

Alvarez-Ponce, D.; Aguilar-Rodriguez, J.; Fares, M. A.

10.1101/552349 — evolutionary biology — Posted on 2019-02-15

1293 Highly Efficient Hypothesis Testing Methods for Regression-type Tests with Correlated Observations and Heterogeneous Variance Structure

Zhang, Y.; Bandyopadhyay, G.; Topham, D. J.; Falsey, A. R.; Qiu, X.

10.1101/552331 — bioinformatics — Posted on 2019-02-15

1294 Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests

10.1101/552364 — zoology — Posted on 2019-02-15

1295 Sequencing red fox Y chromosome fragments to develop phylogenetically informative SNP markers and glimpse male-specific trans-Pacific phylogeography

Sacks, B. N.; Lounsberry, Z.; Rando, H.; Kluepfel, K.; Fain, S.; Brown, S.; Kukekova, A.

10.1101/552323 — genetics — Posted on 2019-02-15

1296 Adaptation and latitudinal gradients in species interactions: nest predation in birds

Freeman, B.; Scholer, M.; Boehm, M.; Heavyside, J.; Schluter, D.

10.1101/552380 — evolutionary biology — Posted on 2019-02-15

1297 Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic Memory.

Turner, D. C.; Seaborne, R. A.; Sharples, A. P.

10.1101/465708 — physiology — Posted on 2019-02-15

1298 Defining the molecular state of human cancer

Sahu, B.; Pihlajamaa, P.; Zhang, K.; Palin, K.; Ahonen, S.; Cervera, A.; Aaltonen, L.; Hautaniemi, S.; Taipale, J.

10.1101/525600 — genomics — Posted on 2019-02-15

1299 FASTCAR: Rapid alignment-free prediction of sequence alignment identity scores using self-supervised general linear models

James, B. T.; Luczak, B. B.; Girgis, H. Z.

10.1101/380824 — bioinformatics — Posted on 2019-02-15

1300 Transcriptional dynamics of bread wheat in response to nitrate and phosphate supply reveal functional divergence of genetic factors involved in nitrate and phosphate signaling

Dissanayake, I.; Rodriguez-Medina, J.; Brady, S.; Tanurdzic, M.

10.1101/551069 — plant biology — Posted on 2019-02-15

1301 Transketolase of Staphylococcus aureus is involved in the control of master regulators of stress response during infection

Tan, X.; Ramond, E.; jamet, a.; Decaux-Tramoni, B.; Dupuis, M.; euphrasie, d.; Tros, F.; Nemazanyy, I.; Ziveri, J.; Nassif, X.; Charbit, A.; Coureuil, M.

10.1101/538900 — microbiology — Posted on 2019-02-15

1302 Comparison Between UMAP and t-SNE for Multiplex-Immunofluorescence Derived Single-Cell Data from Tissue Sections

Wu, D.; Yeong, J.; Tan, G.; Chevrier, M.; Loh, J.; Lim, T.; Chen, J.

10.1101/549659 — bioinformatics — Posted on 2019-02-15

1303 Glutamatergic and cholinergic metabotropic modulation induces plateau potentials in hippocampal OLM interneurons

Hagger-Vaughan, N.; Storm, J. F.

10.1101/508382 — neuroscience — Posted on 2019-02-15

1304 VariantKey - A Reversible Numerical Representation of Human Genetic Variants

Asuni, N.; Wilder, S.

10.1101/473744 — bioinformatics — Posted on 2019-02-15

1305 Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

Wooten, D. J.; Maddox, S. F.; Tyson, D.; Liu, Q.; Lim, J. S.; Sage, J.; Lopez, C.; Quaranta, V.

10.1101/506402 — systems biology — Posted on 2019-02-15

1306 Diversity of photosynthetic picoeukaryotes in eutrophic shallow lakes as assessed by combining flow cytometry cell-sorting and high throughput sequencing

Metz, S.; Lopes dos Santos, A.; Berman, M. C.; Bigeard, E.; Licursi, M.; Not, F.; Lara, E.; Unrein, F.

10.1101/551598 — ecology — Posted on 2019-02-15

1307 Guanine content of microRNAs is associated with their tumor suppressive and oncogenic roles in lung and breast cancers

Cohen, A.; Burgos-Aceves, M. A.; Smith, Y.

10.1101/518472 — cancer biology — Posted on 2019-02-15

1308 Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

Berdan, C. A.; Ho, R.; Lehtola, H. S.; To, M.; Hu, X.; Huffman, T. R.; Petri, Y.; Altobelli, C. R.; Demeulenaere, S. G.; Olzmann, J. A.; Maimone, T. J.; Nomura, D. K.

10.1101/550806 — cancer biology — Posted on 2019-02-15

1309 BRAFV600E Expression in Mouse Neuroglial Progenitors Increase Neuronal Excitability, Cause Appearance of Balloon-like cells, Neuronal Mislocalization, and Inflammatory Immune response.

Goz, R. U.; Silas, A.; Buzel, S.; LoTurco, J. J.

10.1101/544973 — neuroscience — Posted on 2019-02-15

1310 Computer Simulations of the Humoral Immune System Reveal How Imprinting Can Affect Responses to Influenza HA Stalk with Implications for the Design of Universal Vaccines

Anderson, C. S.; Sangster, M. Y.; Yang, H.; Chaudhury, S.; Topham, D. J.

10.1101/346726 — immunology — Posted on 2019-02-15

1311 Trends of Hospitalization in Acute Pancreatitis in Patients in the United States from 2001-2014

Casey, K.; Argo, R.; Bianco, A.

10.1101/547273 — epidemiology — Posted on 2019-02-15

1312 Cerebellar nuclei neurons dictate growth of the cortex through developmental scaling of presynaptic Purkinje cells

Willett, R. T.; Wojcinski, A.; Bayin, N. S.; Lao, Z.; Stephen, D.; Dauber-Decker, K. L.; Wu, Z.; Tessier-Lavigne, M.; Saito, H.; Suzuki, N.; Joyner, A. L.

10.1101/310953 — developmental biology — Posted on 2019-02-15

1313 A fronto-temporo-parietal network disambiguates potential objects of joint attention

Kraemer, P. M.; Görner, M.; Ramezanpour, H.; Dicke, P. W.; Thier, P.

10.1101/542555 — neuroscience — Posted on 2019-02-15

1314 Endogenous and exogenous control of visuospatial selective attention in freely behaving mice

You, W.-K.; Mysore, S. P.

10.1101/550822 — neuroscience — Posted on 2019-02-15

1315 Environmental association identifies candidates for tolerance to low temperature and drought

Lei, L.; Poets, A. M.; Liu, C.; Wyant, S. R.; Hoffman, P. J.; Carter, C. K.; Trantow, R. M.; Shaw, B. G.; Li, X.; Muehlbauer, G. J.; Katagiri, F.; Morrell, P. L.

10.1101/405399 — genomics — Posted on 2019-02-15

1316 Bridging the gap between single cell migration and collective dynamics

Thueroff, F.; Goychuk, A.; Reiter, M.; Frey, E.

10.1101/548677 — biophysics — Posted on 2019-02-15

1317 Functional diversification of hybridoma produced antibodies by CRISPR/HDR genomic engineering

van der Schoot, J. M. S.; Fennemann, F. L.; Valente, M.; Dolen, Y.; Hagemans, I. M.; Becker, A. M. D.; Le Gall, C. M.; van Dalen, D.; Cevirgel, A.; van Bruggen, J. A. C.; Engelfriet, M.; Fransen, M. F.; Caval, T.; Bentlage, A. E. H.; Nederend, M.; Leusen, J. H. W.; Heck, A. J. R.; Vidarsson, G.; Figdor, C. G.; Verdoes, M.; Scheeren, F. A.

10.1101/551382 — bioengineering — Posted on 2019-02-15

1318 Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

Gunner, G.; Cheadle, L.; Johnson, K. M.; Ayata, P.; Badimon, A.; Mondo, E.; Nagy, A.; Liu, L.; Bemiller, S. M.; Kim, K.-w.; Lira, S. A.; Lamb, B. T.; Tapper, A. R.; Ransohoff, R. M.; Greenberg, M. E.; Schaefer, A.; Schafer, D. P.

10.1101/551697 — neuroscience — Posted on 2019-02-15

1319 Evolution of the HIV-1 RRE during natural infection reveals nucleotide changes that correlate with altered structure and increased activity over time

Sherpa, C.; Jackson, P.; Gray, L. R.; Anastos, K.; Le Grice, S. F. J.; Hammarskjold, M.-L.; Rekosh, D.

10.1101/483511 — molecular biology — Posted on 2019-02-15

1320 Deconvolution of bulk blood eQTL effects into immune cell subpopulations

10.1101/548669 — genomics — Posted on 2019-02-15

1321 Delineating and validating higher-order dimensions of psychopathology in the Adolescent Brain Cognitive Development (ABCD) study

Michelini, G.; Barch, D. M.; Tian, Y.; Watson, D.; Klein, D. N.; Kotov, R.

10.1101/548057 — epidemiology — Posted on 2019-02-15

1322 A novel cellular structure in the photoreceptors of insectivorous birds

Tyrrell, L. P.; Teixeira, L. B. C.; Dubielzig, R. R.; Pita, D.; Baumhardt, P.; Moore, B. A.; Fernandez-Juricic, E.

10.1101/551945 — zoology — Posted on 2019-02-15

1323 Electron cryo-microscopy structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome.

Armache, J.-P.; Gamarra, N.; Johnson, S. L.; Leonard, J. D.; Wu, S.; Narlikar, G. J.; Cheng, Y.

10.1101/550970 — biophysics — Posted on 2019-02-15

1324 Associations between depth and micro-diversity within marine viral communities revealed through metagenomics

Hernandes Coutinho, F.; Rosselli, R.; Rodriguez-Valera, F.

10.1101/551291 — microbiology — Posted on 2019-02-15

1325 A high-resolution, chromosome-assigned Komodo dragon genome reveals adaptations in the cardiovascular, muscular, and chemosensory systems of monitor lizards

Lind, A.; Lai, Y. Y. Y.; Mostovoy, Y.; Holloway, A. K.; Iannucci, A.; Mak, A. C.; Fondi, M.; Orlandini, V.; Eckalbar, W. L.; Milan, M.; Rovatsos, M.; Kichigin, I. G.; Makunin, A. I.; Trifonov, V.; Schijlen, E.; Kratochvil, L.; Fani, R.; Jessop, T. S.; Patarnello, T.; Hicks, J. W.; Ryder, O. A.; Mendelson, J. R.; Ciofi, C.; Kwok, P.-Y. A.; Pollard, K. S.; Bruneau, B.

10.1101/551978 — genomics — Posted on 2019-02-15

1326 Low birth weight in Bangladesh and associated maternal and socioeconomic factors: results from a recent nationally-representative survey

Hossain, F. B.; Adhikary, G.; Arafat, Y.; Shawon, M. S. R.

10.1101/546333 — epidemiology — Posted on 2019-02-15

1327 When do big problems far away become smaller than the problems closer to home: Lessons for antimicrobial resistance from Father Ted

Donker, T.; Hopkins, K. L.; Hopkins, S.; Muller-Pebody, B.; Peto, T. E. A.; Johnson, A. P.; Woodford, N.; Crook, D. W.; Walker, A. S.; Robotham, J. V.

10.1101/544593 — epidemiology — Posted on 2019-02-15

1328 Stability of an adaptively controlled pathway maximising specific flux under varying conditions

Overal, G. B.; Planque, R.; Hulshof, J.

10.1101/550343 — systems biology — Posted on 2019-02-15

1329 Abstracted functions for engineering the autonomous growth and formation of patterns

Choksi, A.; Endy, D.

10.1101/549352 — synthetic biology — Posted on 2019-02-15

1330 Changes in anterior and posterior hippocampus differentially predict item-space, item-time, and item-item memory improvement

Lee, J. K.; Fandakova, Y.; Johnson, E. G.; Cohen, N.; Bunge, S. A.; Ghetti, S.

10.1101/551705 — neuroscience — Posted on 2019-02-15

1331 Cryptic inoviruses are pervasive in bacteria and archaea across Earth's biomes

Roux, S.; Krupovic, M.; Daly, R. A.; Borges, A. L.; Nayfach, S.; Schulz, F.; Cheng, J.-F.; Ivanova, N. N.; Bondy-Denomy, J.; Wrighton, K. C.; Woyke, T.; Visel, A.; Kyrpides, N.; Eloe-Fadrosh, E. A.

10.1101/548222 — microbiology — Posted on 2019-02-15

1332 Identification of CP77 as the third orthopoxvirus SAMD9L inhibitor with a unique specificity for a rodent SAMD9L

Zhang, F.; Meng, X.; Townsend, M.; Satheshkumar, P.; Xiang, Y.

10.1101/551556 — microbiology — Posted on 2019-02-15

1333 Phage efficacy in infecting dual-strain biofilms of Pseudomonas aeruginosa

Testa, S.; Berger, S.; Piccardi, P.; Oechslin, F.; Resch, G.; Mitri, S.

10.1101/551754 — microbiology — Posted on 2019-02-15

1334 Absolute measurements of mRNA translation in C. crescentus reveal important fitness costs of vitamin B12 scavenging

Aretakis, J. R.; Gega, A.; Schrader, J. M.

10.1101/552000 — microbiology — Posted on 2019-02-15

1335 Analysis of immunological resistance to primary Mycobacterium tuberculosis infection in humans

Weiner, J.; Domaszewska, T.; Donkor, S.; Hill, P.; Sutherland, J.

10.1101/551432 — immunology — Posted on 2019-02-15

1336 TNFR2 induced priming of NLRP3-inflammasome via RIPK1 leads to pyroptosis in XIAP deficient cells

Knop, J.; Spilgies, L. M.; Rufli, S.; Reinhardt, R.; Vasilikos, L.; Yabal, M.; Jost, P. J.; Wajant, H.; Robinson, M. D.; Kaufmann, T.; Wong, W. W.-L.

10.1101/550749 — immunology — Posted on 2019-02-15

1337 Multiple hormonal signalling pathways function cell-nonautonomously to control protein homeostasis in Caenorhabditis elegans

Gomez Escribano, A. P.; Bono-Yague, J.; Roca, M.; Panadero, J.; Sequedo, M. D.; Saini, R.; Knoelker, H.-J.; Blanca, J. M.; Burguera, J. A.; Lahoz, A.; Canizares, J.; Millan, J. M.; Burton, N.; Vazquez-Manrique, R.

10.1101/551580 — genetics — Posted on 2019-02-15

1338 Executive control of positive and negative information and adolescent depressive symptoms: cross-sectional and longitudinal associations in a population-based cohort.

Lewis, G.; Button, K. S.; Pearson, R. M.; Munafo, M. R.; Lewis, G.

10.1101/548834 — epidemiology — Posted on 2019-02-15

1339 Search for early pancreatic cancer blood biomarkers in five European prospective population biobanks using metabolomics

Fest, J.; Vijfhuizen, L. S.; Goeman, J. J.; Veth, O.; Joensuu, A.; Perola, M.; Mannisto, S.; Ness-Jensen, E.; Hveem, K.; Haller, T.; Tonisson, N.; Mikkel, K.; Metspalu, A.; van Duijn, C. M.; Ikram, A.; Stricker, B. H.; Ruiter, R.; van Eijck, C. H.; van Ommen, G. B.; 't Hoen, P. A.

10.1101/543686 — epidemiology — Posted on 2019-02-15

1340 Spatial distribution of Salmonella enterica in poultry shed environments observed by intensive longitudinal environmental sampling

Crabb, H. K.; Allen, J. L.; Devlin, J. M.; Wilks, C.; Gilkerson, J.

10.1101/547539 — epidemiology — Posted on 2019-02-15

1341 An Exclusively Skewed Distribution of Pediatric Immune Reconstitution Inflammatory Syndrome Towards the Female Sex is Associated with Advanced Acquired Immune Deficiency Syndrome

de Souza Campos Fernandes, R. C.; Louvain de Souza, T.; da Silva Barcellos, T.; Medina-Acosta, E.

10.1101/550129 — epidemiology — Posted on 2019-02-15

1342 Quantifying antibiotic impact on within-host dynamics of extended-spectrum beta-lactamase resistance in hospitalized patients

Niehus, R.; Van Kleef, E.; Mo, Y.; Turlej-Rogacka, A.; Lammens, C.; Carmeli, Y.; Goossens, H.; Tacconelli, E.; Carevic, B.; Malhotra-Kumar, S.; Cooper, B. S.

10.1101/548453 — epidemiology — Posted on 2019-02-15

1343 Estimated incidence of noma \"A biologic indicator of poverty\" in north central Nigeria: A retrospective cross-sectional study

Bello, S. A.; Adeoye, J. A.; Oketade, I.; Akadiri, O.

10.1101/549956 — epidemiology — Posted on 2019-02-15

1344 Model ensembles with different response variables for base and meta models: malaria disaggregation regression combining prevalence and incidence data

Lucas, T. C. D.; Nandi, A.; Nguyen, M.; Rumisha, S.; Battle, K.; Howes, R.; Hendriks, C.; Python, A.; Hancock, P.; Cameron, E.; Gething, P.; Weiss, D.

10.1101/548719 — epidemiology — Posted on 2019-02-15

1345 Treatment utilization and medical problems in a community sample of adult women with anorexia nervosa

Brodrick, B.; Harper, J.; Van Enkevort, E.; McAdams, C.

10.1101/547133 — epidemiology — Posted on 2019-02-15

1346 Evaluating the stoichiometric trait distributions of cultured bacterial populations and uncultured microbial communities

Manzella, M.; Geiss, R.; Hall, E.

10.1101/550681 — ecology — Posted on 2019-02-15

1347 Structure of the SARS-CoV NSP12 polymerase bound to NSP7 and NSP8 co-factors

Kirchdoerfer, R. N.; Ward, A. B.

10.1101/551986 — biophysics — Posted on 2019-02-15

1348 Host_microbe_PPI - R package to analyse intra-species and inter-species protein-protein interactions in the model plant Arabidopsis thaliana

Nussbaumer, T.

10.1101/551275 — bioinformatics — Posted on 2019-02-15

1349 Latent Toxoplasma gondii infection increases soluble mutant huntingtin and promotes neurodegeneration in the YAC128 mouse model of Huntington's disease

Donley, D. W.; Jenkins, T.; Deiter, C.; Campbell, R.; Realing, M.; Chopra, V.; Hersch, S.; Gigley, J. P.; Fox, J.

10.1101/550624 — neuroscience — Posted on 2019-02-15

1350 Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66-independent targeting of NogoA

Lin, C. Y.; Wu, C. L.; Lee, K. Z.; Chen, Y. J.; Zhang, P. H.; Chang, C. Y.; Han, H. J.; Lin, S. Z.; Tsai, H. J.

10.1101/550921 — developmental biology — Posted on 2019-02-15

1351 Rapid sperm capture: High-throughput flagellar waveform analysis

Gallagher, M. T.; Cupples, G.; Ooi, E. H.; Kirkman-Brown, J. C.; Smith, D. J.

10.1101/551267 — cell biology — Posted on 2019-02-15

1352 AligNet: Alignment of Protein-Protein Interaction Networks

Alberich, R.; Alcala, A.; Llabres, M.; Rossello, F.; Valiente, G.

10.1101/551242 — systems biology — Posted on 2019-02-15

1353 Glutathionylation primes soluble GAPDH for late collapse into insoluble aggregates

Zaffagnini, M.; Marchand, C.; Malferrari, M.; Murail, S.; Bonacchi, S.; Genovese, D.; Montalti, M.; Venturoli, G.; Falini, G.; Baaden, M.; Lemaire, S.; Fermani, S.; Trost, P.

10.1101/545921 — plant biology — Posted on 2019-02-15

1354 MRtrix3: A fast, flexible and open software framework for medical image processing and visualisation

Tournier, J.-D.; Smith, R. E.; Raffelt, D. A.; Tabbara, R.; Dhollander, T.; Pietsch, M.; Christiaens, D.; Jeurissen, B.; Yeh, C.-H.; Connelly, A.

10.1101/551739 — neuroscience — Posted on 2019-02-15

1355 Functional ultrasound imaging of deep visual cortex in awake non-human primates

Blaize, K.; Gesnik, M.; Arcizet, F.; Ahnine, H.; Ferrari, U. U.; Deffieux, T.; Pougget, P.; Chavane, F.; Fink, M.; Sahel, J.-A.; Tanter, M.; Picaud, S.

10.1101/551663 — neuroscience — Posted on 2019-02-15

1356 Mesoscale cortical dynamics reflect the interaction of sensory evidence and temporal expectation during perceptual decision-making

Orsolic, I.; Rio, M.; Mrsic-Flogel, T. D.; Znamenskiy, P.

10.1101/552026 — neuroscience — Posted on 2019-02-15

1357 Intracortical dynamics underlying repetitive stimulation predicts changes in network connectivity

Huang, Y.; Hajnal, B.; Entz, L.; Fabo, D.; Herrero, J. L.; Mehta, A. D.; Keller, C. J.

10.1101/548180 — neuroscience — Posted on 2019-02-15

1358 Non-motor effects of subthalamic nucleus stimulation in Parkinson's patients

Sammartino, F.; Marsh, R.; Rezai, A.; Krishna, V.

10.1101/540328 — neuroscience — Posted on 2019-02-15

1359 Data-driven spatial filtering for improved measurement of cortical tracking of multiple representations of speech

Lesenfants, D.; Vanthornhout, J.; Verschueren, E.; Francart, T.

10.1101/551218 — neuroscience — Posted on 2019-02-15

1360 Mutant huntingtin protein alters the response of microglial cells to inflammatory stimuli

Donley, D.; Nelson, R.; Gigley, J.; Fox, J.

10.1101/550913 — neuroscience — Posted on 2019-02-15

1361 A Novel Taxon of RNA Viruses Endemic to Planarian Flatworms

Burrows, J.; Depierreux, D.; Nibert, M. L.; Pearson, B. J.

10.1101/551184 — microbiology — Posted on 2019-02-15

1362 HLA-C-restricted presentation of a conserved bacterial epitope to an innate NK cell receptor

Sim, M. J. W.; Rajagopalan, S.; Altmann, D. M.; Boyton, R. J.; Sun, P. D.; Long, E. O.

10.1101/550889 — immunology — Posted on 2019-02-15

1363 Characterization of single gene copy number variants in schizophrenia

Szatkiewicz, J.; Fromer, M.; Nonneman, R.; Ancalade, N.; Johnson, J.; Stahl, E.; Rees, E.; Bergen, S.; Hultman, C.; Kirov, G.; O'Donovan, M.; Owen, M.; Holmans, P.; Sklar, P.; Sullivan, P.; Purcell, S.; Crowley, J.; Ruderfer, D.

10.1101/550863 — genetics — Posted on 2019-02-15

1364 Semi-quantitative characterisation of mixed pollen samples using MinION sequencing and Reverse Metagenomics (RevMet)

Peel, N.; Dicks, L.; Heavens, D.; Percival-Alwyn, L.; Cooper, C.; Clark, M. D.; Davies, R. G.; Leggett, R. M.; Yu, D. W.

10.1101/551960 — ecology — Posted on 2019-02-15

1365 Assessing different components of biodiversity across a river network using eDNA

Maechler, E.; Little, C. J.; Wuethrich, R.; Alther, R.; Fronhofer, E. A.; Gounand, I.; Harvey, E.; Huerlemann, S.; Walser, J.-C.; Altermatt, F.

10.1101/546549 — ecology — Posted on 2019-02-15

1366 Reticulon and CLIMP-63 control nanodomain organization of peripheral ER tubules

Gao, G.; Zhu, C.; Liu, E.; Nabi, I. R.

10.1101/550715 — cell biology — Posted on 2019-02-15

1367 Immune Responses to Human Induced Pluripotent Stem Cells and their Derived Myogenic Progenitors Are Mediated by Different Mechanisms in Humanized Mice

Benabdallah, B.; Desaulniers-Langevin, C.; Goyer, M.-L.; Colas, C.; Maltais, C.; Li, Y.; Guimond, J. V.; Tremblay, J. P.; Haddad, E.; Beausejour, C.

10.1101/550699 — cell biology — Posted on 2019-02-15

1368 Read-SpaM: assembly-free and alignment-free comparison of bacterial genomes with low sequencing coverage

Lau, A. K.; Leimeister, C.-A.; Morgenstern, B.

10.1101/550632 — bioinformatics — Posted on 2019-02-15

1369 PRECISE: A domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors

Mourragui, S.; Loog, M.; Reinders, M. J.; Wessels, L. F.

10.1101/536797 — bioinformatics — Posted on 2019-02-15

1370 CompScore: boosting structure-based virtual screening performance by incorporating docking scoring functions components into consensus scoring

Perez-Castillo, Y.; Sotomayor-Burneo, S.; Jimenes-Vargas, K.; Gonzalez-Rodriguez, M.; Cruz-Monteagudo, M.; Armijos-Jaramillo, V.; D. S. Cordeiro, M. N.; Borges, F.; Sanchez-Rodriguez, A.; Tejera, E.

10.1101/550590 — bioinformatics — Posted on 2019-02-15

1371 Network-wide abnormalities explain memory variability in hippocampal amnesia

Argyropoulos, G. P. D.; Loane, C.; Roca-Fernandez, A.; Lage-Martinez, C.; Gurau, O.; Irani, S. R.; Butler, C. R.

10.1101/551812 — neuroscience — Posted on 2019-02-15

1372 Unique structural features of the mitochondrial AAA+ protease AFG3L2 reveal the molecular basis for activity in health and disease

Puchades, C.; Ding, B.; Song, A.; Wiseman, R. L.; Lander, G. C.; Glynn, S. E.

10.1101/551085 — molecular biology — Posted on 2019-02-15

1373 Environmental pheromone and endocrine signals correct heterochronic developmental phenotypes caused by insufficient expression of let-7 family microRNAs in C. elegans

Ilbay, O.; Ambros, V.

10.1101/551606 — developmental biology — Posted on 2019-02-15

1374 Alpaca: a kmer-based approach for investigating mosaic structures in microbial genomes

Salazar, A.; Abeel, T.

10.1101/551234 — bioinformatics — Posted on 2019-02-15

1375 Noisy Perturbation Models Distinguish Network Specific from Embedding Variability

Piehler, A.

10.1101/550467 — systems biology — Posted on 2019-02-15

1376 Graph Signal Processing of Low and High-Order Dynamic Functional Connectivity Networks Using EEG Resting-State for Schizophrenia: A Whole Brain Breakdown

Dimitriadis, S. I.

10.1101/551671 — neuroscience — Posted on 2019-02-15

1377 Retrieval Practice Facilitates Judgments of Learning Through Multiple Mechanisms

Chen, X.; Zhang, M.; Liu, X. L.

10.1101/550731 — neuroscience — Posted on 2019-02-15

1378 Robust 3D Bloch-Siegert based B1+ mapping using Multi-Echo General Linear Modelling

Corbin, N.; Acosta-Cabronero, J.; Malik, S. J.; Callaghan, M. F.

10.1101/550509 — neuroscience — Posted on 2019-02-15

1379 BDNF controls bidirectional endocannabinoid-plasticity at corticostriatal synapses

Gangarossa, G.; Perez, S.; Dembitskaya, Y.; Prokin, I.; Berry, H.; Venance, L.

10.1101/550947 — neuroscience — Posted on 2019-02-15

1380 Drosophila carboxypeptidase D (SILVER) is a key enzyme in neuropeptide processing required to maintain locomotor activity levels and survival rate

Pauls, D.; Hamarat, Y.; Trufasu, L.; Schendzielorz, T. M.; Gramlich, G.; Kahnt, J.; Vanselow, J. T.; Schlosser, A.; Wegener, C.

10.1101/551853 — neuroscience — Posted on 2019-02-15

1381 Strategies for understanding dynamic, personalized profiles of host-derived proteins and microbes from human stool

Casavant, E. P.; Dethlefsen, L.; Sankaran, K.; Sprockett, D.; Holmes, S.; Relman, D. A.; Elias, J.

10.1101/551143 — molecular biology — Posted on 2019-02-15

1382 Amino Sugars Modify Antagonistic Interactions between Commensal Oral Streptococci and Streptococcus mutans

Chen, L.; Chakraborty, B.; zou, J.; Burne, R. A.; Zeng, L.

10.1101/551168 — microbiology — Posted on 2019-02-15

1383 An integrative approach identifies direct targets of the late viral transcription complex and an expanded promoter recognition motif in Kaposi's sarcoma-associated herpesvirus

Nandakumar, D.; Glaunsinger, B.

10.1101/550772 — microbiology — Posted on 2019-02-15

1384 Variation in genome context and predatory phenotypes between Bdellovibrio sp. NC01 isolated from soil and B. bacteriovorus type strain HD100

Williams, L. E.; Cullen, N.; DeGiorgis, J. A.; Martinez, K. J.; Mellone, J.; Oser, M.

10.1101/551937 — microbiology — Posted on 2019-02-15

1385 Enterococcus faecium genome dynamics during long-term asymptomatic patient gut colonization

Bayjanov, J. R.; Baan, J.; Rogers, M. R. C.; Troelstra, A.; Willems, R. J. L.; van Schaik, W.

10.1101/550244 — microbiology — Posted on 2019-02-15

1386 The Patchy Distribution of Restriction-Modification System Genes and the Conservation of Orphan Methyltransferases in Halobacteria.

Fullmer, M. S.; Ouellette, M.; Louyakis, A.; Papke, R. T.; Gogarten, J. P.

10.1101/551721 — genomics — Posted on 2019-02-15

1387 Rare Microbial Taxa Emerge When Communities Collide: Freshwater and Marine Microbiome Responses to Experimental Seawater Intrusion

Rocca, J. D.; Simonin, M.; Wright, J.; Washburne, A.; Bernhardt, E. S.

10.1101/550756 — ecology — Posted on 2019-02-15

1388 SWITCH 1/DYAD is a novel WINGS APART-LIKE antagonist that maintains sister chromatid cohesion in meiosis

Yang, C.; Hamamura, Y.; Sofroni, K.; Boewer, F.; Stolze, S. C.; Nakagami, H.; Schnittger, A.

10.1101/551317 — cell biology — Posted on 2019-02-15

1389 Identification of lncRNAs associated with early stage breast cancer and their prognostic implications

Arunagiri Kuha, D. M. R.; Patel, K.; Korivi Jyothi, S.; Balaiah, M.; Sundersingh, S.; Velusami, S.; Thangarajan, R.; Pandey, A.; Chatterjee, A.; Gowda, H.; Mani, S.

10.1101/543397 — cancer biology — Posted on 2019-02-15

1390 Ordered Hexagonal Patterns via Notch-Delta Signaling

Kessler, D. A.; Levine, H.; Teomy, E.

10.1101/550657 — biophysics — Posted on 2019-02-15

1391 Ion Condensation onto Ribozyme is Site-Specific and Fold-Dependent

Hori, N.; Denesyuk, N. A.; Thirumalai, D.

10.1101/551994 — biophysics — Posted on 2019-02-15

1392 Pixel personality for dense object tracking in a 2D honeybee hive

Bozek, K.; Hebert, L.; Mikheyev, A. S.; Stephens, G. J.

10.1101/549006 — animal behavior and cognition — Posted on 2019-02-15

1393 Autonomously replicating linear plasmids facilitate the analysis of replication origin function in Candida albicans

Bijlani, S.; Thevandavakkam, M. A.; Tsai, H.-J.; Berman, J.

10.1101/551127 — molecular biology — Posted on 2019-02-15

1394 Characterization of pyruvate dehydrogenase complex E1 alpha and beta subunits of Mycoplasma synoviae

Bao, S.; Ding, X.; Yu, S.; Ding, C.

10.1101/551176 — microbiology — Posted on 2019-02-15

1395 Using the NCBI AMRFinder Tool to Determine Antimicrobial Resistance Genotype-Phenotype Correlations Within a Collection of NARMS Isolates

Feldgarden, M.; Brover, V.; Haft, D. H.; Prasad, A. B.; Slotta, D. J.; Tolstoy, I.; Tyson, G. H.; Zhao, S.; Hsu, C.-H.; McDermott, P. F.; Tadesse, D. A.; Morales, C.; Simmons, M.; Tillman, G.; Wasilenko, J.; Folster, J. P.; Klimke, W.

10.1101/550707 — microbiology — Posted on 2019-02-15

1396 Loss of TET proteins in regulatory T cells unleashes effector function

Yue, X.; Lio, C.-W. J.; Samaniego-Castruita, D.; Li, X.; Rao, A.

10.1101/551093 — immunology — Posted on 2019-02-15

1397 Testing pleiotropy vs. separate QTL in multiparental populations

Boehm, F. J.; Chesler, E. J.; Yandell, B. S.; Broman, K. W.

10.1101/550939 — genetics — Posted on 2019-02-15

1398 Climate change is predicted to disrupt patterns of local adaptation in wild and cultivated maize

Aguirre-Liguori, J. A.; Ramirez-Barahona, S.; Tiffin, P.; Eguiarte, L. E.

10.1101/549675 — evolutionary biology — Posted on 2019-02-15

1399 Introgressive and horizontal acquisition of Wolbachia by hybridizing Drosophila yakuba-clade hosts and horizontal transfer of phage loci between distantly related Wolbachia

Cooper, B. S.; Vanderpool, D.; Conner, W. R.; Matute, D. R.; Turelli, M.

10.1101/551036 — evolutionary biology — Posted on 2019-02-15

1400 Global patterns of seed germination after ingestion by mammals

Torres, D. A.; Castano, J.; Carranza-Quiceno, J. A.

10.1101/549162 — ecology — Posted on 2019-02-15

1401 Mapping of long-term impact of conventional and organic soil management on resident and active fractions of rhizosphere communities of barley (Hordeum vulgare)

Harkes, P.; Suleiman, A.; van den Elsen, S.; de Haan, J.; Holterman, M.; Kuramae, E.; Helder, J.

10.1101/546192 — ecology — Posted on 2019-02-15

1402 Mutations in the Insulator Protein Suppressor of Hairy Wing Induce Genome Instability

Hsu, S.-J.; Stow, E. C.; Simmons, J. R.; Wallace, H. A.; Mancheno Lopez, A.; Stroud, S.; Labrador-San Jose, M.

10.1101/551002 — developmental biology — Posted on 2019-02-15

1403 Retinoic acid promotes in vitro development of haploid germ cells from pre-pubertal porcine spermatogenic cells

Deng, S.-L.; Lian, Z.-X.; Yu, K.; Zhang, Y.; Zhang, B.-L.; Wu, H.-Y.; Han, D.-P.; Liu, Y.-X.; Wang, S.-T.

10.1101/552083 — developmental biology — Posted on 2019-02-15

1404 Direct Evidence for Glucose Consumption Acceleration by Carbonates in Cultured Cells

Sorimachi, K.

10.1101/551259 — cell biology — Posted on 2019-02-15

1405 NNAlign_MA; semi-supervised MHC peptidome deconvolution for accurate characterization of MHC binding motifs and improved T cell epitope prediction

Alvarez, B.; Reynisson, B.; Barra, C.; Buus, S.; Ternette, N.; Connelley, T.; Andreatta, M.; Nielsen, M.

10.1101/550673 — bioinformatics — Posted on 2019-02-15

1406 multiPhATE: bioinformatics pipeline for functional annotation of phage isolates

Zhou, C. E.; Malfatti, S. A.; Kimbrel, J. A.; Philipson, C. W.; McNair, K. E.; Hamilton, T. C.; Edwards, R. A.; Souza, B. E.

10.1101/551010 — bioinformatics — Posted on 2019-02-15

1407 Tracking activity patterns of a multispecies community of gymnotiform weakly electric fish in their neotropical habitat

Henninger, J.; Sinz, F.; Krahe, R.; Benda, J.

10.1101/550814 — animal behavior and cognition — Posted on 2019-02-15

1408 Attacked from above and below, new observations of cooperative and solitary predators on roosting cave bats

Tanalgo, K. C.; Waldien, D. L.; Monfort, N.; Hughes, A. C.

10.1101/550582 — animal behavior and cognition — Posted on 2019-02-15

1409 Organizational properties of a functional mammalian cis-regulome

Chaudhri, V.; Dienger-Stambaugh, K.; Wu, Z.; Shrestha, M.; Singh, H.

10.1101/550897 — systems biology — Posted on 2019-02-15

1410 Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease

Donley, D.; Realing, M.; Gigley, J.; Fox, J.

10.1101/550905 — neuroscience — Posted on 2019-02-15

1411 Paternal age affects offspring's behavior possibly via an epigenetic mechanism recruiting a transcriptional repressor REST

Yoshizaki, K.; Koike, T.; Kimura, R.; Kikkawa, T.; Oki, S.; Koike, K.; Mochizuki, K.; Inada, H.; Kobayashi, H.; Matsui, Y.; Kono, T.; Osumi, N.

10.1101/550095 — neuroscience — Posted on 2019-02-15

1412 Photorhabdus Virulence Cassettes: extracellular multi-protein needle complexes for delivery of small protein effectors into host cells.

Vlisidou, I.; Hapeshi, A.; Healey, J. R. J.; Smart, K.; Yang, G.; Waterfield, N. R.

10.1101/549964 — microbiology — Posted on 2019-02-15

1413 Flower-like patterns in multi-species biofilms

Xiong, L.; Cao, Y.; Cooper, R.; Rappel, W.-J.; Hasty, J.; Tsimring, L.

10.1101/550996 — microbiology — Posted on 2019-02-15

1414 Identification of functional variants for platelet CD36 expression by Massively Parallel Reporter Assay.

Madan, N.; Ghazi, A.; Kong, X.; Chen, E.; Shaw, C.; Edelstein, L.

10.1101/550871 — genomics — Posted on 2019-02-15

1415 Variable Genome Evolution in Fungi After Transposon-Mediated Amplification of a Housekeeping Gene

Dhillon, B.; Kema, G. H. J.; Hamelin, R.; Bluhm, B. H.; Goodwin, S.

10.1101/550798 — genomics — Posted on 2019-02-15

1416 Leveraging genetic interaction for adverse drug-drug interaction prediction

Qian, S.; Liang, S.; Yu, H.

10.1101/455006 — bioinformatics — Posted on 2019-02-15

1417 Detecting RyR clusters with CaCLEAN: influence of spatial distribution and structural heterogeneity

Ladd, D.; Tilunaite, A.; Soeller, C.; Roderick, H. L.; Crampin, E.; Rajagopal, V.

10.1101/549683 — bioengineering — Posted on 2019-02-15

1418 Large-scale brain network dynamics provide a measure of psychosis and anxiety in 22q11.2 deletion syndrome.

Zoeller, D.; Sandini, C.; Karahanoglu, F. I.; Padula, M. C.; Schaer, M.; Eliez, S.; Van De Ville, D.

10.1101/551796 — neuroscience — Posted on 2019-02-15

1419 Brain tissue properties and morphometry assessment after chronic complete spinal cord injury

Hug, A.; Bernini, A.; Wang, H.; Lutti, A.; Jende, J.; Boettinger, M.; Weber, M.-A.; Weidner, N.; Lang, S.

10.1101/547620 — neuroscience — Posted on 2019-02-15

1420 A T6SS trans-kingdom effector is required for the delivery of a novel antibacterial toxin in Pseudomonas aeruginosa

Berni, B.; Soscia, C.; Djermoun, S.; Ize, B.; Bleves, S.

10.1101/551929 — microbiology — Posted on 2019-02-15

1421 PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells

Mallol, A.; Guirola, M.; Payer, B.

10.1101/551895 — developmental biology — Posted on 2019-02-15

1422 Noradrenergic responsiveness preserves selective attention across the adult life span

Dahl, M. J.; Mather, M. M.; Sander, M. C.; Werkle-Bergner, M.

10.1101/551879 — neuroscience — Posted on 2019-02-15

1423 Electrophysiology and transcriptomics reveal two photoreceptor classes and complex visual integration in Hirudo verbana

Stowasser, A.; Stahl, A.; Benoit, J. B.; Wagenaar, D. A.

10.1101/552018 — neuroscience — Posted on 2019-02-15

1424 Evaluations of short telomere risk-associated single nucleotide polymorphisms in telomerase reverse transcriptase gene on telomere length maintenance

Xu, J.; Trudeau, M. A.; Sandford, A. J.; Wong, J. M.

10.1101/552133 — genetics — Posted on 2019-02-15

1425 Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators

Godwin, W. C.; Hoffmann, G. F.; Gray, T. J.; Hughes, R. M.

10.1101/551788 — biochemistry — Posted on 2019-02-15

1426 A Quasi Birth-and-Death Model For Tumor Recurrence

M. Santana, L.; Bhanot, G.; Ganesan, S.

10.1101/551770 — cancer biology — Posted on 2019-02-15

1427 Competitive inhibitors of Ras effector binding

Ernst, A.; Wiechmann, S.; Maisonneuve, P.; Grebbin, B. M.; Hoffmeister, M.; Kaulich, M.; Clevers, H.; Rajalingam, K.; Kourinov, I.; Farin, H. F.; Sicheri, F.

10.1101/548750 — cancer biology — Posted on 2019-02-15

1428 Neural ensemble dynamics in dorsal motor cortex during speech in people with paralysis

Stavisky, S. D.; Willett, F. R.; Murphy, B. A.; Rezaii, P.; Avansino, D. T.; Memberg, W. D.; Miller, J. P.; Kirsch, R. F.; Hochberg, L. R.; Ajiboye, A. B.; Shenoy, K. V.; Henderson, J. M.

10.1101/505487 — neuroscience — Posted on 2019-02-15

1429 A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes

Sun, Y.; Kim, E.; Felt, S. A.; Taylor, L.; Agarwal, D.; Grant, G.; Lopez, C.

10.1101/349001 — microbiology — Posted on 2019-02-15

1430 Early Detection of Neurological Dysfunction Using Blood Cell Transcript Profiles

Moni, M. A.; Rana, H. K.; Islam, M. B.; Ahmed, M. B.; Lio, P.; Hasan, M. A. M.; Huq, F.; Quinn, J.

10.1101/483016 — bioinformatics — Posted on 2019-02-15

1431 JHU-2545 Selectively Shields Salivary Glands and Kidneys during PSMA-Targeted Radiotherapy

Nedelcovych, M. T.; Dash, R. P.; Wu, Y.; Choi, E. Y.; Lapidus, R. S.; Majer, P.; Abou, D.; Penet, M.-F.; Nikolopoulou, A.; Amor-Coarasa, A.; Babich, J.; Thorek, D. L.; Rais, R.; Kratochwil, C.; Slusher, B. S.

10.1101/457085 — pharmacology and toxicology — Posted on 2019-02-15

1432 Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics

Chen, S. Y.; Osimiri, L. C.; Chevalier, M. W.; Bugaj, L. J.; Ng, A. H.; Stewart-Ornstein, J.; Neves, L. T.; El-Samad, H.

10.1101/548255 — systems biology — Posted on 2019-02-15

1433 Population genetic data of the 21 autosomal STRs included in GlobalFilerTM kit of a population sample from the Kingdom of Bahrain

Al Snan, N.; Messaoudi, S. M.; R. Babuc, S. R. B.; Bakhiet, M.

10.1101/550400 — genetics — Posted on 2019-02-15

1434 Biochemical properties and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia

Tlili, H.; Hanen, N.; Ben Arfa, A.; Boubakri, A.; Neffati, M.; Buonocore, D.; Verri, M.; Dossena, M.; Doria, E.

10.1101/551515 — plant biology — Posted on 2019-02-15

1435 Allergic inflammation hinders synergistic viral-bacterial co-infection in C57BL/6 mice

LeMessurier, K.; Iverson, A.; Chang, T.-C.; Palipane, M.; Vogel, P.; Rosch, J.; Samarasinghe, A.

10.1101/550459 — pathology — Posted on 2019-02-15

1436 Crystal Structure of the Dog Allergen Can f 6

Clayton, G. M.; White, J.; Kappler, J. W.; Chan, S. K.

10.1101/551549 — molecular biology — Posted on 2019-02-15

1437 Genome-wide identification and analysis of A-to-I RNA editing events in the malignantly transformed cell lines from BEP2D induced by α-particles radiation

Liu, Q.; Li, H.; You, L.; Li, T.; Li, L.; Zhou, P.; Bo, X.; Chen, H.; Chen, X.; Hu, Y.

10.1101/551499 — genetics — Posted on 2019-02-15

1438 Extracellular matrix mineralization in the mouse osteoblast-like cell line MC3T3-E1 is regulated by actin cytoskeleton reorganization and non-protein molecules secreted from the cells themselves

Suzuki, H.; Tatei, K.; Ohshima, N.; Sato, S.; Izumi, T.

10.1101/551531 — biochemistry — Posted on 2019-02-15

1439 Whole genomic sequencing as a tool for diagnosis of drug and multidrug-resistance tuberculosis in an endemic region in Mexico

Madrazo-Moyza, C. F.; Cancino-Munoz, I.; Cuevas-Cordoba, B.; Gonzalez-Covarrubias, V.; Barbosa-Amezcua, M.; Soberon, X.; Muniz-Salazar, R.; Martinez-Guarneros, A.; Backer, C.; Zarrabal-Meza, J.; Sampieri-Ramirez, C.; Lauzardo, M.; Enciso-Moreno, A.; Comas, I.; Zenteno-Cuevas, R.

10.1101/551481 — microbiology — Posted on 2019-02-15

1440 Associations between absolute neutrophil count and lymphocyte-predominant breast cancer

Yoon, C. I.; Park, S. E.; Cha, Y. J.; Bae, S. J.; Cha, C. H.; Lee, D. Y.; Ahn, S. G.; Jeong, J.

10.1101/551465 — immunology — Posted on 2019-02-15

1441 The use of mixture-density networks in the emulation of complex epidemiological individual-based models

Davis, C.; Hollingsworth, D.; Caudron, Q.; Irvine, M. A.

10.1101/551440 — epidemiology — Posted on 2019-02-15

1442 Thrombin cleaves and activates the protease-activated receptor 2 dependent on thrombomodulin co-receptor availability

Heuberger, D. M.; Franchini, A. G.; Madon, J.; Schuepbach, R. A.

10.1101/550137 — molecular biology — Posted on 2019-02-15

1443 Epilepsy in children in Papua New Guinea: a longitudinal cohort study

Mond, C.; Vince, J. D.; Duke, T.

10.1101/551416 — epidemiology — Posted on 2019-02-15

1444 Architectural traits constrain the evolution of unisexual flowers and sexual segregation within inflorescences: an interspecific approach

Torices, R.; Afonso, A.; Anderberg, A. A.; Gomez, J. M.; Mendez, M.

10.1101/356147 — evolutionary biology — Posted on 2019-02-15

1445 Dynamics of living cells in a cytomorphological state space

Chang, A. Y.; Marshall, W. F.

10.1101/549246 — biophysics — Posted on 2019-02-14

1446 Cooperative riboregulation in living cells through allosteric programming of toehold activation

Rodrigo, G.; Prakash, S.; Shen, S.; Majer, E.; Daros, J.-A.; Jaramillo, A.

10.1101/009688 — synthetic biology — Posted on 2019-02-12

1447 Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells

Lu, C.-H.; Chen, W.-T.; Hsieh, C.-H.; Kuo, Y.-Y.; Chao, C.-Y.

10.1101/548552 — cancer biology — Posted on 2019-02-14

1448 Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

Berdan, C. A.; Ho, R.; Lehtola, H. S.; To, M.; Hu, X.; Huffman, T. R.; Petri, Y.; Altobelli, C. R.; Demeulenaere, S. G.; Olzmann, J. A.; Maimone, T. J.; Nomura, D. K.

10.1101/550806 — cancer biology — Posted on 2019-02-14

1449 Incentive value and spatial certainty combine additively to determine visual priorities

Garner, K. G.; Bowman, H.; Raymond, J. E.

10.1101/188045 — neuroscience — Posted on 2019-02-14

1450 Marked compositional changes in harvestmen assemblages in Amazonian forest islands induced by a mega dam

Tourinho, A. L.; Benchimol, M.; Porto, W.; Peres, C.; Storck Tonon, D.

10.1101/542969 — ecology — Posted on 2019-02-14

1451 Dynamic Aha1 Co-Chaperone Binding to Human Hsp90

Oroz, J.; Blair, L. J.; Zweckstetter, M.

10.1101/550228 — biophysics — Posted on 2019-02-14

1452 Identification of genetic markers for cortical areas using a Random Forest classification routine and the Allen Mouse Brain Atlas

Waters, J.; Weed, N.; Bakken, T.; Graddis, N.; Gouwens, N.; Millman, D.; Hawrylycz, M.

10.1101/549519 — neuroscience — Posted on 2019-02-14

1453 Novel risk genes and mechanisms implicated by exome sequencing of 2,572 individuals with pulmonary arterial hypertension

Zhu, N.; Pauciulo, M. W.; Welch, C. L.; Lutz, K. A.; Coleman, A. W.; Gonzaga-Jauregui, C.; Wang, J.; Grimes, J. M.; Martin, L. J.; He, H.; PAH Biobank, ; Shen, Y.; Chung, W. K.; Nichols, W. C.

10.1101/550327 — genetics — Posted on 2019-02-14

1454 Effects of acute lying and sleep deprivation on the behavior of lactating dairy cows

Kull, J. A.; Proudfoot, K. L.; Pighetti, G. M.; Bewley, J. M.; O'Hara, B. F.; Donohue, K. D.; Krawczel, P. D.

10.1101/549378 — animal behavior and cognition — Posted on 2019-02-14

1455 Bayesian abundance estimation from genetic mark-recapture data when not all sites are sampled: an example with the bowhead whale

Frasier, T. R.; Petersen, S. D.; Postma, L.; Johnson, L.; Heide-Jorgensen, M. P.; Ferguson, S. H.

10.1101/549394 — zoology — Posted on 2019-02-14

1456 The regulatory factor ELF1 triggers a critical wave of transcription in the antiviral response to type I interferon

Seifert, L. L.; Si, C.; Ballentine, S.; Saha, D.; de Vries, M.; Wang, G.; Sadic, M.; Briley, A.; Schaefer, U.; Moulton, H.; Garcia-Sastre, A.; Tripathi, S.; Rosenberg, B. R.; Dittmann, M.

10.1101/549485 — immunology — Posted on 2019-02-14

1457 Nondisjunction and unequal spindle organization accompany the drive of Aegilops speltoides B chromosomes

Houben, A.; Wu, D.; Ruban, A.; Fuchs, J.; Macas, J.; Novak, P.; Vaio, M.; Zhou, Y.

10.1101/547612 — genetics — Posted on 2019-02-14

1458 Speed, accuracy, sensitivity and quality control choices for detecting clinically relevant microbes in whole blood from patients.

Thornton, J. E.; Watts, G. S.; Youens-Clark, K.; Cranmer, L. D.; Hurwitz, B. L.

10.1101/549477 — bioinformatics — Posted on 2019-02-14

1459 Odour conditioning of positive affective states: Rats can learn to associate an odour with being tickled

Bombail, V.; Jerome, N.; Lam, H.; Muszlak, S.; Meddle, S.; Lawrence, A. B.; Nielsen, B. L.

10.1101/549436 — animal behavior and cognition — Posted on 2019-02-14

1460 Investigating on-road lane maintenance and speed regulation in post-stroke driving: a pilot case-control study

Zhou, H.; Sun, Q.; Blane, A.; Hughes, B.; Falkmer, T.; Xia, J.

10.1101/549410 — scientific communication and education — Posted on 2019-02-14

1461 Sox17 expression in endocardium precursor cells regulates heart development in mice

10.1101/548289 — developmental biology — Posted on 2019-02-14

1462 Multi-Neuromodulator Measurements across Fronto-Striatal Network Areas of the Behaving Macaque using Solid-Phase Microextraction

Hassani, S.-A.; Lendor, S.; Boyaci, E.; Pawliszyn, J.; Womelsdorf, T.

10.1101/534651 — neuroscience — Posted on 2019-02-14

1463 Environmental association identifies candidates for tolerance to low temperature and drought

Lei, L.; Poets, A. M.; Liu, C.; Wyant, S. R.; Hoffman, P. J.; Carter, C. K.; Trantow, R. M.; Shaw, B. G.; Li, X.; Muehlbauer, G. J.; Katagiri, F.; Morrell, P. L.

10.1101/405399 — genomics — Posted on 2019-02-14

1464 Krüppel-like factor gene function in the ctenophore Mnemiopsis suggests an ancient role in promoting cell proliferation in metazoan stem cell niches

Presnell, J. S.; Browne, W. E.

10.1101/527002 — developmental biology — Posted on 2019-02-14

1465 A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity

Sheppard, E. C.; Rogers, S.; Harmer, N. J.; Chahwan, R.

10.1101/548628 — biochemistry — Posted on 2019-02-14

1466 Differential brain mechanisms of selection and maintenance of information during working memory

Quentin, R.; King, J.-R.; Sallard, E.; Fishman, N.; Thompson, R.; Buch, E.; Cohen, L. G.

10.1101/283234 — neuroscience — Posted on 2019-02-14

1467 Novel childhood experience suggests eccentricity drives organization of human visual cortex

Gomez, J.; Barnett, M.; Grill-Spector, K.

10.1101/415729 — neuroscience — Posted on 2019-02-14

1468 Species abundance information improves sequence taxonomy classification accuracy

Kaehler, B. D.; Bokulich, N.; McDonald, D.; Knight, R.; Caporaso, J. G.; Huttley, G. A.

10.1101/406611 — bioinformatics — Posted on 2019-02-14

1469 Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

Berdan, C. A.; Ho, R.; Lehtola, H. S.; To, M.; Hu, X.; Huffman, T. R.; Petri, Y.; Altobelli, C. R.; Demeulenaere, S. G.; Olzmann, J. A.; Maimone, T. J.; Nomura, D.

10.1101/550806 — cancer biology — Posted on 2019-02-14

1470 Identification of circadian rhythms in Nannochloropsis species using bioluminescence reporter lines

Poliner, E.; Cummings, C.; Newton, L.; Farre, E. M.

10.1101/550954 — molecular biology — Posted on 2019-02-14

1471 Nutrient stoichiometry shapes microbial coevolution

Larsen, M. L.; Wilhelm, S. W.; Lennon, J. T.

10.1101/183657 — microbiology — Posted on 2019-02-14

1472 Shugoshin protects centromere pairing and promotes segregation of non-exchange partner chromosomes in meiosis

Previato, L.; Evatt, J. M.; Chuong, H. H.; Kurdzo, E. L.; Eyster, C. A.; Gladstone, M. N.; Gomez-H, L.; Llano, E.; Meyer, R.; Pendas, A. M.; Pezza, R. J.; Dawson, D. S.

10.1101/263384 — cell biology — Posted on 2019-02-14

1473 Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

Chang, C.-L.; Weigel, A. V.; Ioannou, M. S.; Pasolli, H. A.; Xu, C. S.; Peale, D. R.; Shtengel, G.; Freeman, M.; Hess, H. F.; Blackstone, C.; Lippincott-Schwartz, J.

10.1101/544023 — cell biology — Posted on 2019-02-14

1474 Egalitarian binding partners, Dynein Light Chain and Bicaudal-D, act sequentially to link mRNA to the Dynein motor

Goldman, C. H.; Veeranan-Karmegam, R.; Neiswender, H.; Gonsalvez, G. B.

10.1101/550277 — cell biology — Posted on 2019-02-14

1475 Novel Algorithms for the Taxonomic Classification of Metagenomic Linked Reads

Danko, D. C.; Meleshko, D.; Bezdan, D.; Mason, C. C.; Hajirasouliha, I.

10.1101/549667 — bioinformatics — Posted on 2019-02-14

1476 SCFAs-induced GLP-1 Secretion Links the Regulation of Gut Microbiome on Hepatic Lipogenesis in Chickens

ZHANG, J.; Sun, Y. s.; Zhao, L.; Chen, T.; Fan, M.; Jiao, H. C.; Zhao, J.; Wang, X.; Li, F. c.; Li, H.; Lin, H.

10.1101/549857 — microbiology — Posted on 2019-02-14

1477 EpiMethylTag simultaneously detects ATAC-seq or ChIP-seq signals with DNA methylation

Lhoumaud, P.; Sethia, G.; Izzo, F.; Badri, S.; Cornwell, M.; Kim, K.-T.; Landau, D.; Skok, J.

10.1101/549550 — genomics — Posted on 2019-02-14

1478 SCANVIS: a tool for SCoring, ANnotating and VISualing splice junctions

Agius, P.; Geiger, H.; Robine, N.

10.1101/549261 — bioinformatics — Posted on 2019-02-14

1479 Cannabis use, depression and self-harm: phenotypic and genetic relationships

Hodgson, K.; Coleman, J. R.; Hagenaars, S. P.; Purves, K. L.; Choi, S. W. L.; O'Reilly, P. F.; Breen, G. F.; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Lewis, C. M.

10.1101/549899 — genetics — Posted on 2019-02-14

1480 MakeHub: Fully automated generation of UCSC Genome Browser Assembly Hubs

Hoff, K. J.

10.1101/550145 — bioinformatics — Posted on 2019-02-14

1481 An orthogonal c-Cbl recognition mode targets LynA for rapid degradation and builds specificity into the LynA checkpoint

Brian, B. F.; Nunez, M. G.; Schwertfeger, K. L.; Freedman, T. S.

10.1101/550053 — biochemistry — Posted on 2019-02-14

1482 Impacts of reduced inorganic N:P ratio on three distinct plankton communities in the Humboldt upwelling system

Spilling, K.; Camarena Gomez, M. T.; Lipsewers, T.; Martinez-Varela, A.; Diaz-Rosas, F.; Eronen-Rasimus, E.; Silva, N.; Dassow, P. v.; Montecino, V.

10.1101/550046 — plant biology — Posted on 2019-02-14

1483 Visible light-triggered NO generation from Naphthalimide-based probe for photoreceptor-mediated plant root growth regulation

Biswas, S.; Upadhyay, N.; Kar, D.; Datta, S.; Koner, A. L.

10.1101/550004 — plant biology — Posted on 2019-02-14

1484 Pharmacodynamic inoculum effect from the perspective of bacterial population modeling

Baeder, D. Y.; Regoes, R. R.

10.1101/550368 — pharmacology and toxicology — Posted on 2019-02-14

1485 Plasma pNfH differentiate SBMA from ALS

Lombardi, V.; Bombaci, A.; Zampedri, L.; Lu, C.-H.; Malik, B.; Zetterberg, H.; Heslegrave, A.; Rinaldi, C.; Greensmith, L.; Hanna, M.; Malaspina, A.; Fratta, P.

10.1101/549576 — neuroscience — Posted on 2019-02-14

1486 Altered brain function in anorexia nervosa and bulimia nervosa: A hierarchical series of task-based fMRI meta-analyses

Liu, B.; Liu, J.; Ju, Y.; Wang, M.; Liu, T.; Zhang, Y.; Li, L.; Potenza, M.; Barron, D. S.

10.1101/550301 — neuroscience — Posted on 2019-02-14

1487 Robust Genome-Wide Ancestry Inference for Heterogeneous Datasets and Ancestry Facial Imaging based on the 1000 Genomes Project

Li, J.; Conzalez Zarzar, T. B.; White, J. D.; Indencleef, K.; Hoskens, H.; Ortega Castrillon, A.; Nauwelaers, N.; Zaidi, A. A.; Eller, R. J.; Gunther, T.; Svensson, E. M.; Jakobsson, M.; Walsh, S.; Van Steen, K.; Shriver, M. D.; Claes, P.

10.1101/549881 — genetics — Posted on 2019-02-14

1488 Isolation and characterization of live yeast cells from ancient vessels as a tool in bio-archeology

Aouizerat, T.; Gutman, I.; Paz, Y.; Maeir, A. M.; Gadot, Y.; Gelman, D.; Szitenberg, A.; Drori, E.; Pinkus, A.; Schoemann, M.; Kaplan, R.; Ben-Gedalya, T.; Coppenhagen-Glazer, S.; Reich, E.; Saragovi, A. S.; Lipschits, O.; Klutstein, M.; Hazan, R.

10.1101/549840 — ecology — Posted on 2019-02-14

1489 Potato genotypes differentially alter the expression of Phytophthora infestans effectors during PAMP-mediated resistance induction

THOMAS, C. M.; LE BOULCH, P.; ANDRIVON, D.; VAL, F.

10.1101/547984 — plant biology — Posted on 2019-02-14

1490 Dilated Saliency U-Net for White Matter Hyperintensities Segmentation using Irregularity Age Map

Jeong, Y.; Rachmadi, M. F.; Valdes Hernandez, M. d. C.; Komura, T.

10.1101/550517 — neuroscience — Posted on 2019-02-14

1491 A method for genome-wide genealogy estimation for thousands of samples

Speidel, L.; Forest, M.; Shi, S.; Myers, S.

10.1101/550558 — genetics — Posted on 2019-02-14

1492 Clonal Architecture of the Epidermis: Homeostasis Limits Keratinocyte Evolution

Schenck, R. O.; Kim, E.; Bravo, R.; West, J.; Leedham, S.; Shibata, D.; Anderson, A. R. A.

10.1101/548131 — evolutionary biology — Posted on 2019-02-14

1493 The genome of Auriculariopsis ampla sheds light on fruiting body development and wood-decay of bark-inhabiting fungi

Almasi, E.; Sahu, N.; Krizsan, K.; Balint, B.; Kovacs, G. M.; Kiss, B.; Cseklye, J.; Drula, E.; Henrissat, B.; Nagy, I.; Chovatia, M.; Adam, C.; LaButti, K.; Lipzen, A.; Riley, R.; Grigoriev, I. V.; Nagy, L. G.

10.1101/550103 — evolutionary biology — Posted on 2019-02-14

1494 Resilience trinity: safeguarding ecosystem services across three different time horizons and decision contexts

Weise, H.; Auge, H.; Baessler, C.; Baerlund, I.; Bennett, E. M.; Berger, U.; Bohn, F.; Bonn, A.; Borchardt, D.; Brand, F.; Chatzinotas, A.; Corstanje, R.; De Laender, F.; Dietrich, P.; Dunker, S.; Durka, W.; Fazey, I.; Groeneveld, J.; Guilbaud, C. S. E.; Harms, H.; Harpole, S.; Harris, J. A.; Jax, K.; Jeltsch, F.; Johst, K.; Joshi, J.; Klotz, S.; Kuehn, I.; Kuhlicke, C.; Mueller, B.; Radchuk, V.; Reuter, H.; Rinke, K.; Schmitt-Jansen, M.; Seppelt, R.; Singer, A. S.; Standish, R. J.; Thulke, H.-H.; Tietjen, B.; Weitere, M.; Wirth, C.; Wolf, C.; Grimm, V.

10.1101/549873 — ecology — Posted on 2019-02-14

1495 Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells

Lu, C.-H.; Chen, W.-T.; Hsieh, C.-H.; Kuo, Y.-Y.; Chao, C.-Y.

10.1101/548552 — cancer biology — Posted on 2019-02-14

1496 Chiroptical Kirigami Modulators for Terahertz Circular Dichroism Spectroscopy of Biomaterials

Choi, W. J.; Cheng, G.; Huang, Z.; Zhang, S.; Norris, T. B.; Kotov, N. A.

10.1101/549600 — biophysics — Posted on 2019-02-14

1497 External location of touch is constructed post-hoc based on limb choice

Maij, F.; Medendorp, W. P.; Heed, T.

10.1101/549832 — neuroscience — Posted on 2019-02-14

1498 Adaptation to binocular anticorrelation results in increased neural excitability

Rideaux, R.; Michael, E.; Welchman, A. E.

10.1101/549949 — neuroscience — Posted on 2019-02-14

1499 Mixed-polarity random-dot stereograms alter GABA and Glx concentration in the early visual cortex

Rideaux, R.; Goncalves, N.; Welchman, A. E.

10.1101/549980 — neuroscience — Posted on 2019-02-14

1500 Preferential Binding of Anti-Neutrophil Cytoplasmic Antibodies to an Unexpected Epitope of a Chimeric Proteinase 3 Mutant

Casal Moura, M.; Thompson, G. E.; Nelson, D. A.; Fussner, L. A.; Hummel, A. M.; Jenne, D. E.; Emerling, D.; Volkmuth, W.; Fervenza, F. C.; Kallenberg, C. G. M.; Langford, C. A.; McCune, J. W.; Merkel, P. A.; Monach, P. A.; Seo, P.; Spiera, R. F.; St. Clair, E. W.; Ytterberg, S. R.; Stone, J. H.; Robinson, W. H.; Pang, Y.-P.; Specks, U.

10.1101/549063 — immunology — Posted on 2019-02-14

1501 A Differentially Methylated CpG Site in the IL4 Gene Associated with Anti-FVIII Inhibitor Antibody Development in Hemophilia A

Barbosa de Souza, T.; Louvain de Souza, T.; dos Santos Ferreira, C.; Figueiredo Osorio da Silva, C.; Rossetti, L. C.; Marchione, V. D.; De Brasi, C. D.; Medina-Acosta, E.

10.1101/550566 — genetics — Posted on 2019-02-14

1502 The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.

Ward, J.; Tunbridge, E. M.; Sandor, C.; Lyall, L.; Ferguson, A.; Strawbridge, R. J.; Lyall, D. M.; Cullen, B.; Graham, N.; Johnston, K. J. A.; Webber, C.; Escott-Price, V.; O'Donovan, M. P.; Pell, J. P.; Bailey, M. E. S.; Harrison, P. J.; Smith, D. J.

10.1101/549931 — genetics — Posted on 2019-02-14

1503 Ohana: detecting selection in multiple populations by modelling ancestral admixture components

Cheng, J. Y.; Racimo, F.; Nielsen, R.

10.1101/546408 — bioinformatics — Posted on 2019-02-14

1504 Pesticide exposure and adverse health effects associated with farm work in Northern Thailand

Forte, C. A.; Colacino, J. A.; Polemi, K. M.; Guytingco, A.; Peraino, N. J.; Jindaphong, S.; Kaviya, T.; Westrick, J.; Neitzel, R.; Nambunmee, K.

10.1101/549618 — pharmacology and toxicology — Posted on 2019-02-14

1505 Key aspects of neurovascular control mediated by specific populations of inhibitory cortical interneurons

Lee, L. M.; Boorman, L.; Glendenning, E.; Christmas, C.; Sharp, P.; Redgrave, P.; Shabir, O.; Bracci, E.; Berwick, J.; Howarth, C.

10.1101/550269 — neuroscience — Posted on 2019-02-14

1506 Propagating patterns of activity across motor cortex facilitate movement initiation

Balasubramanian, K.; Papadourakis, V.; Liang, W.; Takahashi, K.; Best, M. D.; Suminski, A. J.; Hatsopoulos, N. G.

10.1101/549568 — neuroscience — Posted on 2019-02-14

1507 The successful invasion of the European earwig across North America reflects adaptations to thermal regimes but not mean temperatures

Tourneur, J.-C.; Meunier, J.

10.1101/550319 — evolutionary biology — Posted on 2019-02-14

1508 ICONIC MANAKINS AND DESPICABLE GRACKLES: COMPARING BIRD-RELATED CULTURAL ECOSYSTEM SERVICES ACROSS BIRDWATCHERS, FARMERS, AND URBANITES IN NORTHWESTERN COSTA RICA

Echeverri, A.; Naidoo, R.; Karp, D. S.; Chan, K. M. A.; Zhao, J.

10.1101/548982 — ecology — Posted on 2019-02-14

1509 ENDOSOMAL MEMBRANE TENSION CONTROLS ESCRT-III-DEPENDENT INTRA-LUMENAL VESICLE FORMATION

Roux, A.; Gruenberg, J.; Mercier, V.; Larios, J.; Goujon, A.; Matile, S.; Molinard, G.

10.1101/550483 — cell biology — Posted on 2019-02-14

1510 Using time causal quantifiers to characterize Sleep stages

Mateos, D. M.; Gomez-Ramirez, J.; Rosso, O. A.

10.1101/550152 — neuroscience — Posted on 2019-02-14

1511 Spatio-temporal dynamics of face perception

Muukkonen, I.; Olander, K.; Numminen, J.; Salmela, V.

10.1101/550038 — neuroscience — Posted on 2019-02-14

1512 Microbiotyping the sinonasal microbiome

Bassiouni, A.; Paramasivan, S.; Shiffer, A.; Dillon, M. R.; Cope, E.; Cooksley, C.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/549311 — microbiology — Posted on 2019-02-14

1513 Nuclear hormone receptor NHR-49 shapes immuno-metabolic response of Caenorhabditis elegans to Enterococcus faecalis infection.

Dasgupta, M.; Shashikanth, M.; Bojanala, N.; Gupta, A.; Javed, S.; Singh, V.

10.1101/549907 — immunology — Posted on 2019-02-14

1514 Detection of Base Analogs Incorporated During DNA Replication by Nanopore Sequencing

Georgieva, D.; Liu, Q.; Wang, K.; Egli, D.

10.1101/549220 — genomics — Posted on 2019-02-14

1515 Genome-wide association study identifies 44 independent genomic loci for self-reported adult hearing difficulty in the UK Biobank cohort

Wells, H. R. R.; Freidin, M. B.; Zainul Abidin, F. N.; Payton, A.; Dawes, P.; Munro, K. J.; Morton, C. C.; Moore, D. R.; Dawson, S. J.; Wiliams, F. M.

10.1101/549071 — genetics — Posted on 2019-02-14

1516 Species dispersal mediates opposing influences of a branching network on genetic variation in a metapopulation

Chiu, M.-C.; Li, B.; Nukazawa, K.; Carvajal, T.; Watanabe, K.

10.1101/550194 — ecology — Posted on 2019-02-14

1517 Thrombin cleaves and activates the protease-activated receptor 2 dependent on thrombomodulin co-receptor availability

Schuepbach, R. A.; Heuberger, D. M.; Franchini, A. G.; Madon, J.

10.1101/550137 — molecular biology — Posted on 2019-02-14

1518 Isolation of Full Size BAC Inserts by DNA Gap Repair in E. coli

Lyozin, G.; Brunelli, L.

10.1101/549634 — molecular biology — Posted on 2019-02-14

1519 Red Sea SAR11 and Prochlorococcus Single-cell Genomes Reflect Globally Distributed Pangenomes

Thompson, L. R.; Haroon, M. F.; Shibl, A. A.; Cahill, M. J.; Ngugi, D. K.; Williams, G. J.; Morton, J.; Knight, R.; Goodwin, K. D.; Stingl, U.

10.1101/549816 — microbiology — Posted on 2019-02-14

1520 Efficacy of PCV vaccine is primarily mediated by controlling pneumococcal colonisation density

German, E. L.; Solorzano, C.; Sunny, S.; Dunne, F.; Gritzfeld, J. F.; Mitsi, E.; Nikolaou, E.; Hyder-Wright, A. D.; Collins, A. M.; Gordon, S. B.; Ferreira, D.

10.1101/547703 — microbiology — Posted on 2019-02-14

1521 Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene

Saferali, A.; Yun, J. H.; Parker, M. M.; Sakornsakolpat, P.; Chase, R. P.; Lamb, A.; Hobbs, B. D.; Boezen, M. H.; Dai, X.; de Jong, K.; Beaty, T. H.; Wei, W.; Zhou, X.; Silverman, E. K.; Cho, M. H.; Castaldi, P. J.; Hersh, C. P.; COPDGene Investigators, and the International COPD Genetics Consortium Investigators,

10.1101/549626 — genetics — Posted on 2019-02-14

1522 Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

Chaikuad, A.; Koschade, S. E.; Stolz, A.; Zivkovic, K.; Shaid, S.; Pohl, C.; Ren, H.; Lambert, L. J.; Cosford, N. D. P.; Brandts, C. H.; Knapp, S.

10.1101/550111 — biochemistry — Posted on 2019-02-14

1523 Linear Input as a Fundamental Motif of Brain Connectivity Organization

O'Rawe, J. F.; Leung, H.-C.

10.1101/549345 — neuroscience — Posted on 2019-02-14

1524 Social Instability is an Effective Chronic Stress Paradigm for both Male and Female Mice

Yohn, C. N.; Ashamalla, S. A.; Bokka, L.; Gergues, M. M.; Garino, A.; Samuels, B. A.

10.1101/550525 — neuroscience — Posted on 2019-02-14

1525 Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver

Brazhnik, K.; Sun, S.; Alani, O.; Kinkhabwala, M.; Wolkoff, A. W.; Maslov, A. Y.; Dong, X.; Vijg, J.

10.1101/547893 — genomics — Posted on 2019-02-14

1526 The Genetic Basis of Transcriptional and Spatial Heterogeneity of Squamous Features in Pancreatic Ductal Adenocarcinoma

Hayashi, A.; Fan, J.; Chen, R.; Makohon-Moore, A. P.; Zhong, Y.; Hong, J.; Sakamoto, H.; Attiyeh, M. A.; Kohutek, Z. A.; Zhang, L.; Huang, J.; Boumiza, A.; Kappagantula, R.; Baez, P.; Wood, L. D.; Hruban, R. H.; Marta, L.; Chadalavada, K.; Nanjangud, G. J.; Basturk, O.; Klimstra, D. S.; Overholtzer, M.; Iacobuzio-Donahue, C. A.

10.1101/548354 — cancer biology — Posted on 2019-02-14

1527 Metacognition facilitates the exploitation of unconscious brain states

Cortese, A.; Lau, H.; Kawato, M.

10.1101/548941 — neuroscience — Posted on 2019-02-14

1528 Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images using a Convolutional Neural Network Scheme

Malla, C. U. P.; Valdes-Hernandez, M. d. C.; Rachmadi, M. F.; Komura, T.

10.1101/544858 — neuroscience — Posted on 2019-02-14

1529 Lipopolysaccharide (LPS) induces increased epidermal green autofluorescence of mouse

Li, Y.; Zhang, M.; Tao, Y.; Ying, W.

10.1101/501189 — biophysics — Posted on 2019-02-14

1530 Survey of severe fever with thrombocytopenia syndrome virus covert infection for healthy people in Henan Province, China

Du, Y.; Cheng, N.; Li, Y.; Wang, H.; You, A.; Su, J.; Nie, Y.; Ma, H.; Xu, B.; Huang, X.

10.1101/550426 — epidemiology — Posted on 2019-02-14

1531 Human extinction learning is accelerated by an angiotensin antagonist via ventromedial prefrontal cortex and its connections with basolateral amygdala

Zhou, F.; Geng, Y.; Xin, F.; Li, J.; Feng, P.; Liu, C.; Zhao, W.; Feng, T.; Guastella, A.; Kendrick, K.; Becker, B.

10.1101/512657 — clinical trials — Posted on 2019-02-14

1532 The essential role played by B cells in supporting protective immunity against Trichuris muris infection is dependent on host genetic background and is independent of antibody

Sahputra, R.; Ruckerl, D.; Couper, K.; Muller, W.; Else, K.

10.1101/550434 — immunology — Posted on 2019-02-14

1533 Anopheles gambiae TEP1 forms a complex with the coiled-coil domain of LRIM1/APL1C following a conformational change in the thioester domain

Baxter, R. H. G.; Williams, M.; Contet, A.; Levashina, E. A.

10.1101/550475 — immunology — Posted on 2019-02-14

1534 Integrated multi-omics analysis to study the effects of simulated weightlessness on rhesus macaques (Macaca mulatta)

Zhang, P.; Shao, L.; Zhang, J.; Li, W.; Fan, G.; Zhou, Y.; Kan, G.; Liu, H.; Li, W.; Wang, F.; Chu, X.; Han, P.; Peng, L.; Liu, X.; Chen, J.; Liang, X.; Ji, J.; Du, S.; Mei, Z.; Li, R.; Xu, X.; Chen, S.; Liu, X.; Chen, X.

10.1101/513382 — physiology — Posted on 2019-02-14

1535 Principles of Meiotic Chromosome Assembly

Schalbetter, S. A.; Fudenberg, G.; Baxter, J.; Pollard, K. S.; Neale, M. J.

10.1101/442038 — molecular biology — Posted on 2019-02-14

1536 Inferring rates of metastatic dissemination using stochastic network models

Gerlee, P.; Johansson, M.

10.1101/352096 — cancer biology — Posted on 2019-02-14

1537 Aicardi-Goutieres Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

Deasy, S. K.; Uehara, R.; Vodnala, S. K.; Yang, H. H.; Dass, R. A.; Hu, Y.; Lee, M. P.; Crouch, R. J.; Hunter, K. W.

10.1101/550418 — cancer biology — Posted on 2019-02-14

1538 Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics

Chen, S. Y.; Osimiri, L. C.; Chevalier, M. W.; Bugaj, L. J.; Ng, A. H.; Stewart-Ornstein, J.; Neves, L. T.; El-Samad, H.

10.1101/548255 — systems biology — Posted on 2019-02-14

1539 Effect of set up protocols on the accuracy of alchemical free energy calculation over a set of ACK1 inhibitors

Granadino-Roldan, J. M.; Mey, A. S. J. S.; Perez, J. J.; Bosisio, S.; Rubio-Martinez, J.; Michel, J.

10.1101/333120 — molecular biology — Posted on 2019-02-14

1540 Clustering and correlations: Inferring resilience from spatial patterns in ecosystems

Sankaran, S.; Majumder, S.; Viswanathan, A.; Guttal, V.

10.1101/233429 — ecology — Posted on 2019-02-14

1541 Single cell profiling of the VMH reveals a sexually dimorphic regulatory node of energy expenditure

van Veen, J. E.; Kammel, L. G.; Bunda, P. C.; Shum, M.; Reid, M. S.; Park, J. W.; Zhang, Z.; Massa, M. G.; Arneson, D.; Hrncir, H.; Liesa, M.; Arnold, A. P.; Yang, X.; Correa, S. M.

10.1101/549725 — neuroscience — Posted on 2019-02-14

1542 Dynamics of visual contextual interactions is altered in Parkinson's disease

Vanegas, M. I.; Blangero, A.; Galvin, J. E.; Di Rocco, A.; Quartarone, A.; Ghilardi, M. F.; Kelly, S. P.

10.1101/549691 — neuroscience — Posted on 2019-02-14

1543 De novo assembly and annotation of Asiatic lion (Panthera leo persica) genome

Mitra, S.; Sreenivas, A.; Sowpati, D. T.; Kumar, A. S.; Awasthi, G.; Kumar, M.; Tabasum, W.; Gaur, A.

10.1101/549790 — genomics — Posted on 2019-02-14

1544 Activated thiol Sepharose-based proteomic approach to globally quantify protein oxidation

Xu, Y.; Neel, B.

10.1101/549709 — biochemistry — Posted on 2019-02-14

1545 Unmatched level of molecular convergence among deeply divergent complex multicellular fungi

Merenyi, Z.; Prasanna, A. N.; Zheng, W.; Kovacs, K.; Hegedus, B.; Balint, B.; Papp, B.; Townsend, J. P.; Nagy, L. G.

10.1101/549758 — evolutionary biology — Posted on 2019-02-14

1546 Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

Brandt, R.; Sell, T.; Luethen, M.; Uhlitz, F.; Klinger, B.; Riemer, P.; Giesecke, C.; Schulze, S.; El-Shimy, I. A.; Kunkel, D.; Fauler, B.; Mielke, T.; Mages, N.; Herrmann, B. G.; Sers, C.; Bluethgen, N.; Morkel, M.

10.1101/340844 — cell biology — Posted on 2019-02-14

1547 Human DNA polymerase delta is a pentameric complex with dimeric p12 subunit: Implications in enzyme architecture and PCNA interaction

Khandagale, P.; Peroumal, D.; Manohar, K.; Acharya, N.

10.1101/525485 — biochemistry — Posted on 2019-02-14

1548 Multi-Neuromodulator Measurements across Fronto-Striatal Network Areas of the Behaving Macaque using Solid-Phase Microextraction

Hassani, S.-A.; Lendor, S.; Boyaci, E.; Pawliszyn, J.; Womelsdorf, T.

10.1101/534651 — neuroscience — Posted on 2019-02-13

1549 Intervention-Induced Changes in Cortical Connectivity and Activity in Severe Chronic Hemiparetic Stroke

Wilkins, K. B.; Dewald, J. P. A.; Yao, J.

10.1101/547083 — neuroscience — Posted on 2019-02-13

1550 Evolutionary Implications of Anoxygenic Phototrophy in the Bacterial Phylum Candidatus Eremiobacterota (WPS-2)

Ward, L. M.; Cardona, T.; Holland-Moritz, H.

10.1101/534180 — evolutionary biology — Posted on 2019-02-13

1551 Accelerating Dissociative Events in Molecular Dynamics Simulations by Selective Potential Scaling

Deb, I.; Frank, A. T.

10.1101/547307 — biophysics — Posted on 2019-02-13

1552 Indexing De Bruijn graphs with minimizers

Marchet, C.; Kerbiriou, M.; Limasset, A.

10.1101/546309 — bioinformatics — Posted on 2019-02-13

1553 Mouse Academy: high-throughput automated training and trial-by-trial behavioral analysis during learning

Qiao, M.; Zhang, T.; Segalin, C.; Sam, S.; Perona, P.; Meister, M.

10.1101/467878 — animal behavior and cognition — Posted on 2019-02-13

1554 The international sinonasal microbiome study (ISMS): a multi-centre, international characterization of sinonasal bacterial ecology

Paramasivan, S.; Bassiouni, A.; Shiffer, A.; Dillon, M. R.; Cope, E.; Cooksley, C.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/548743 — microbiology — Posted on 2019-02-13

1555 A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

Milaneschi, Y.; Peyrot, W. J.; Nivard, M. G.; Mbarek, H.; Boomsma, D. I.; Penninx, B. W.

10.1101/516013 — genomics — Posted on 2019-02-13

1556 Arenaviridae exoribonuclease presents genomic RNA edition capacity.

Yekwa, E.; Aphibanthammakit, C.; Carnec, X.; Picard, C.; Canard, B.; Baize, S.; Ferron, F.

10.1101/541698 — biochemistry — Posted on 2019-02-13

1557 Assessment of kinship detection using RNA-seq data.

Blay, N.; Casas, E.; Galvan-Femenia, I.; Graffelman, J.; de Cid, R.; Vavouri, T.

10.1101/546937 — genomics — Posted on 2019-02-13

1558 The length of the expressed 3' UTR is an intermediate molecular phenotype linking genetic variants to complex diseases

Mariella, E.; Marotta, F.; Grassi, E.; Gilotto, S.; Provero, P.

10.1101/540088 — genetics — Posted on 2019-02-13

1559 Differential immune gene expression associated with contemporary range expansion of two invasive rodents in Senegal

Charbonnel, N.; Galan, M.; Tatard, C.; Loiseau, A.; Diagne, C. A.; Dalecky, A.; Parrinello, H.; Rialle, S.; Severac, D.; Brouat, C.

10.1101/442160 — ecology — Posted on 2019-02-13

1560 Structural insights into SETD3-mediated histidine methylation on β-actin

Guo, Q.; Liao, S.; Kwiatkowski, S.; Tomaka, W.; Yu, H.; Wu, G.; Tu, X.; Min, J.; Drozak, J.; Xu, C.

10.1101/476705 — biochemistry — Posted on 2019-02-13

1561 METASPACE: A community-populated knowledge base of spatial metabolomes in health and disease

Alexandrov, T.; Ovchinnikova, K.; Palmer, A.; Kovalev, V.; Tarasov, A.; Stuart, L.; Nigmetzianov, R.; Fay, D.; Key METASPACE Contributors,

10.1101/539478 — systems biology — Posted on 2019-02-13

1562 Weak modulation of thalamic discharge by basal ganglia output in association with a reaching task

Schwab, B. C.; Kase, D.; Zimnik, A.; Rosenbaum, R.; Rubin, J. E.; Turner, R. S.

10.1101/546598 — neuroscience — Posted on 2019-02-13

1563 Changes in Ovary Transcriptome and Alternative Splicing at Estrus from Xiang Pigs with Large and Small Litter Size

Zhang, F. P.; Ran, X. Q.

10.1101/547810 — molecular biology — Posted on 2019-02-13

1564 Rate variation in the evolution of non-coding DNA associated with social evolution in bees

Rubin, B. E.; Jones, B. M.; Hunt, B.; Kocher, S. D.

10.1101/461079 — evolutionary biology — Posted on 2019-02-13

1565 Distinguishing biological from technical sources of variation by leveraging multiple methylation datasets

Thompson, M.; Chen, Z. J.; Rahmani, E.; Halperin, E.

10.1101/521146 — bioinformatics — Posted on 2019-02-13

1566 Aversive learning strengthens episodic memory in both adolescents and adults

Cohen, A. O.; Matese, N. G.; Filimontseva, A.; Shen, X.; Shi, T. C.; Livne, E.; Hartley, C. A.

10.1101/547331 — animal behavior and cognition — Posted on 2019-02-13

1567 Whitening of odor representations by the wiring diagram of the olfactory bulb

Wanner, A. A.; Friedrich, R. W.

10.1101/515411 — neuroscience — Posted on 2019-02-13

1568 iDamage: a method to integrate modified DNA into the yeast genome

Maslowska, K.; Laureti, L.; Pages, V.

10.1101/510966 — molecular biology — Posted on 2019-02-13

1569 Translating antibiotic prescribing into antimicrobial resistance in the environment: a hazard characterisation case study

Singer, A. C.; Xu, Q.; Keller, V. D.

10.1101/539536 — microbiology — Posted on 2019-02-13

1570 scAlign: a tool for alignment, integration and rare cell identification from scRNA-seq data

Johansen, N.; Quon, G.

10.1101/504944 — bioinformatics — Posted on 2019-02-13

1571 Measures of neural similarity

Bobadilla-Suarez, S.; Ahlheim, C.; Mehrotra, A.; Panos, A.; Love, B. C.

10.1101/439893 — neuroscience — Posted on 2019-02-13

1572 An organoleptic survey of meads made with lactic acid-producing yeasts

Peepall, C.; Nickens, D. G.; Vinciguerra, J.; Bochman, M. L.

10.1101/445296 — microbiology — Posted on 2019-02-13

1573 Expression changes confirm predicted single nucleotide variants affecting mRNA splicing

Mucaki, E. J.; Rogan, P. K.

10.1101/549089 — genomics — Posted on 2019-02-13

1574 Transcriptional initiation and mechanically driven propagation of a tissue morphogenetic wave during axis elongation

Bailles, A.; Collinet, C.; Philippe, J.-M.; Lenne, P.-F.; Munro, E.; Lecuit, T.

10.1101/430512 — developmental biology — Posted on 2019-02-13

1575 Transcriptional signatures of progressive neuropathology in transgenic tau and amyloid mouse models.

Castanho, I.; Murray, T. K.; Hannon, E.; Jeffries, A.; Walker, E.; Laing, E.; Baulf, H.; Harvey, J.; Randall, A.; Moore, K.; O'Neill, P.; Lunnon, K.; Collier, D. A.; Ahmed, Z.; O'Neill, M. J.; Mill, J.

10.1101/548578 — genomics — Posted on 2019-02-13

1576 Comprehensive network analysis reveals alternative splicing-related lncRNAs in hepatocellular carcinoma

Wang, J.; Chen, Y.; Xu, K.; Mo, Y.-y.; Zhou, Y.

10.1101/548263 — bioinformatics — Posted on 2019-02-13

1577 Alterations of redox and iron metabolism accompany development of HIV latency.

Shytaj, I. L.; Lucic, B.; Forcato, M.; Billingsley, J. M.; Bosinger, S.; Stanic, M.; Gregoretti, F.; Antonelli, L.; Oliva, G.; Frese, C.; Trifunovic, A.; Galy, B.; Eibl, C.; Silvestri, G.; Bicciato, S.; Savarino, A.; Lusic, M.

10.1101/549014 — molecular biology — Posted on 2019-02-13

1578 Data Driven Modelling of a Chemically Defined Growth Medium for Cupriavidus necator H16

Azubuike, C. C.; Edwards, M. G.; Gatehouse, A. M. R.; Howard, T. P.

10.1101/548891 — microbiology — Posted on 2019-02-13

1579 Unpacking conditional neutrality: genomic signatures of selection on conditionally beneficial and conditionally deleterious mutations

Mee, J. A.; Yeaman, S.

10.1101/549329 — evolutionary biology — Posted on 2019-02-13

1580 Parasite intensity is driven by temperature in a wild bird

Mennerat, A.; Charmantier, A.; HURTREZ-BOUSSES, S.; Perret, P.; Lambrechts, M. M.

10.1101/323311 — ecology — Posted on 2019-02-13

1581 Dynamic representations of faces in the human ventral visual stream link visual features to behaviour

Dima, D. C.; Singh, K. D.

10.1101/394916 — neuroscience — Posted on 2019-02-13

1582 Critical Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis

Bosl, K.; Ianevski, A.; Than, T. T.; Andersen, P. I.; Kuivanen, S.; Teppor, M.; Zusinaite, E.; Dumpis, U.; Vitkauskiene, A.; Cox, R. J.; Kallio-Kokko, H.; Bergqvist, A.; Tenson, T.; Oksenych, V.; Bjoras, M.; Anthonsen, M. W.; Shum, D.; Kaarbo, M.; Vapalahti, O.; Windisch, M. P.; Superti-Furga, G.; Snijder, B.; Kainov, D.; Kandasamy, R. K.

10.1101/548909 — immunology — Posted on 2019-02-13

1583 Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system

Lackie, R.; Razzaq, A.; Farhan, S. M. K.; Moshitzky, G.; Beraldo, F. H.; Lopes, M. H.; Maciejewski, A.; Gros, R.; Fan, J.; Choy, W.-Y.; Greenberg, D.; Martins, V. R.; Duennwald, M.; Soreq, H.; Prado, V. F.; Prado, M. A. M.

10.1101/258673 — cell biology — Posted on 2019-02-13

1584 Bridging the gap between single cell migration and collective dynamics

Thueroff, F.; Goychuk, A.; Reiter, M.; Frey, E.

10.1101/548677 — biophysics — Posted on 2019-02-13

1585 Does the heart forget? Modulation of cardiac activity induced by inhibitory control over emotional memories

Legrand, N.; Etard, O.; Vandevelde, A.; Pierre, M.; Viader, F.; Clochon, P.; Doidy, F.; Peschanski, D.; Eustache, F.; Gagnepain, P.

10.1101/376954 — neuroscience — Posted on 2019-02-13

1586 Efficient inverse graphics in biological face processing

Yildirim, I.; Belledonne, M.; Freiwald, W.; Tenenbaum, J.

10.1101/282798 — neuroscience — Posted on 2019-02-13

1587 Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA

Levin, T. C.; Goldspiel, B. P.; Malik, H. S.

10.1101/383018 — microbiology — Posted on 2019-02-13

1588 The N-end Rule Pathway and Ubr1 enforce protein compartmentalization via N-terminally-encoded cellular location signals

Tran, A.

10.1101/392373 — cell biology — Posted on 2019-02-13

1589 mRNA structure regulates protein expression through changes in functional half-life

Mauger, D. M.; Cabral, B. J.; Presnyak, V.; Su, S. V.; Reid, D. W.; Goodman, B.; Link, K.; Khatwani, N.; Reynders, J.; Moore, M. J.; McFadyen, I. J.

10.1101/549022 — molecular biology — Posted on 2019-02-13

1590 Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

Brandt, R.; Sell, T.; Luethen, M.; Uhlitz, F.; Klinger, B.; Riemer, P.; Giesecke, C.; Schulze, S.; El-Shimy, I. A.; Fauler, B.; Mielke, T.; Mages, N.; Herrmann, B. G.; Sers, C.; Bluethgen, N.; Morkel, M.; Kunkel, D.

10.1101/340844 — cell biology — Posted on 2019-02-13

1591 Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

Ahmad, S. T.; Rogers, A. D.; Chen, M. J.; Dixit, R.; Adnani, L.; Frankiw, L.; Lawn, S. O.; Blough, M. D.; Alshehri, M.; Wu, W.; Robbins, S. M.; Cairncross, G.; Schuurmans, C.; Chan, J.

10.1101/335984 — cancer biology — Posted on 2019-02-13

1592 Virtual ChIP-seq: Predicting transcription factor binding by learning from the transcriptome

Karimzadeh, M.; Hoffman, M. M.

10.1101/168419 — bioinformatics — Posted on 2019-02-13

1593 Experimental increases in glucocorticoids alter function of the HPA axis in wild red squirrels without negatively impacting survival and reproduction

van Kesteren, F.; Delehanty, B.; Westrick, S. E.; Palme, R.; Boonstra, R.; Lane, J. E.; Boutin, S.; McAdam, A. G.; Dantzer, B.

10.1101/309278 — zoology — Posted on 2019-02-13

1594 Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics

Chen, S. Y.; Osimiri, L. C.; Chevalier, M. W.; Bugaj, L. J.; Ng, A. H.; Stewart-Ornstein, J.; Neves, L. T.; El-Samad, H.

10.1101/548255 — systems biology — Posted on 2019-02-13

1595 HEXOKINASE 1 Glycolytic Action Fuels Post-Germinative Seedling Growth

Ganpudi, A.; Romanowski, A.; Halliday, K. J.

10.1101/548990 — plant biology — Posted on 2019-02-13

1596 The Telomerase Reverse Transcriptase (TERT) and p53 Regulate Mammalian PNS and CNS Axon Regeneration downstream of c-Myc

Ma, J.-J.; Xu, R.-J.; Ju, X.; Wang, W.-H.; Luo, Z.-P.; Liu, C.-M.; Yang, L.; Li, B.; Chen, J.-Q.; Meng, B.; Yang, H.-L.; Zhou, F.-Q.; Saijilafu,

10.1101/547026 — neuroscience — Posted on 2019-02-13

1597 Global Signal Regression Strengthens Association between Resting-State Functional Connectivity and Behavior

Li, J.; Kong, R.; Liegeois, R.; Orban, C.; Tan, Y.; Sun, N.; Holmes, A. J.; Sabuncu, M. R.; Ge, T.; Yeo, B. T. T.

10.1101/548644 — neuroscience — Posted on 2019-02-13

1598 Metacognition facilitates the exploitation of unconscious brain states

Cortese, A.; Lau, H.; Kawato, M.

10.1101/548941 — neuroscience — Posted on 2019-02-13

1599 Of hands, tools, and exploding dots: How different action states and effects separate visuomotor memories

Schween, R.; Langsdorf, L.; Taylor, J. A.; Hegele, M.

10.1101/548602 — neuroscience — Posted on 2019-02-13

1600 Blood and Brain Gene Expression Trajectories Underlying Neuropathology and Cognitive Impairment in Neurodegeneration

Iturria-Medina, Y.; Khan, A. F.; Adewale, Q.

10.1101/548974 — neuroscience — Posted on 2019-02-13

1601 N-cadherin-Presented Slit Repulsive-Cues Direct Collective Schwann cell Migration

Hoving, J. J. A.; Harford-Wright, E.; Wingfield-Digby, P.; Cattin, A.-L.; Campana, M.; Morgan, T. L.; Quereda, V.; Torchiaro, E.; Lloyd, A. C.

10.1101/549030 — molecular biology — Posted on 2019-02-13

1602 Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

Lampe, L.; Jentzsch, M.; Levashina, E. A.

10.1101/548784 — molecular biology — Posted on 2019-02-13

1603 Sweet revenge - Streptococcus pyogenes showcases first example of immune evasion through specific IgG glycan hydrolysis

Naegeli, A.; Bratanis, E.; Karlsson, C.; Shannon, O.; Kalluru, R.; Linder, A.; Malmström, J.; Collin, M.

10.1101/544064 — microbiology — Posted on 2019-02-13

1604 A Deficiency in SUMOylation Activity Disrupts Multiple Pathways Leading to Neural Tube and Heart Defects in Xenopus Embryos

Bertke, M. M.; Dubiak, K. M.; Cronin, L.; Zeng, E.; Huber, P. W.

10.1101/549105 — genomics — Posted on 2019-02-13

1605 Activity-dependent regulation of the proapoptotic BH3-only gene egl-1 in a living neuron pair in C. elegans

Pierce, J. T.; Cohn, J.; Dwivedi, V.; Zarate, N.; Horvitz, R.

10.1101/548925 — genetics — Posted on 2019-02-13

1606 Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance

Wooten, M.; Snedeker, J.; Nizami, Z.; Yang, X.; Ranja, R.; Urban, E.; Kim, J. M.; Gall, J.; Xiao, J.; Chen, X.

10.1101/242768 — developmental biology — Posted on 2019-02-13

1607 Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration

Pena-Jimenez, D.; Fontenete, S.; Megias, D.; Fustero-Torre, C.; Grana-Castro, O.; Castellana, D.; Loewe, R.; Perez-Moreno, M.

10.1101/548768 — cell biology — Posted on 2019-02-13

1608 Isolation of cardiomyocytes undergoing mitosis with complete cytokinesis

Milliron, H.-y. Y.; Weiland, M. J.; Kort, E. J.; Jovinge, S.

10.1101/549212 — cell biology — Posted on 2019-02-13

1609 Variable Retention of Differentiation-specific DNA Replication Timing in Human Pediatric Leukemia

Rivera-Mulia, J. C.; Sasaki, T.; Trevilla-Garcia, C.; Nakamichi, N.; Knapp, D. J. H. F.; Hammond, C.; Chang, B.; Tyner, J. W.; Devidas, M.; Zimmerman, J.; Klein, K.; Somasundaram, V.; Druker, B.; Gruber, T.; Koren, A.; Eaves, C. J.; Gilbert, D. M.

10.1101/549196 — cancer biology — Posted on 2019-02-13

1610 Protoporphyrin IX is a dual inhibitor of p53/MDM2 and p53/MDM4 interactions and induces apoptosis in B-cell chronic lymphocytic leukaemia cells

Jiang, L.; Malik, N.; Acedo, P.; Zawacka-Pankau, J.

10.1101/548875 — cancer biology — Posted on 2019-02-13

1611 Exosome-mediated MIR211 modulates tumor microenvironment via the DUSP6-ERK5 axis and contributes to BRAFV600E inhibitor resistance in melanoma.

Lee, B.; Sahoo, A.; Marchica, J.; Sawada, J.; Sahoo, S.; Layng, F. I. A. L.; Finlay, D.; Mazar, J.; Joshi, P.; Komatsu, M.; Vuori, K.; Powis, G.; de Jong, P. R.; Ray, A.; Perera, R. J.

10.1101/548818 — cancer biology — Posted on 2019-02-13

1612 Dynamics of living cells in a cytomorphological state space

Chang, A. Y.; Marshall, W. F.

10.1101/549246 — biophysics — Posted on 2019-02-13

1613 SpectralTAD: an R package for defining a hierarchy of Topologically Associated Domains using spectral clustering

Cresswell, K. G.; Stansfield, J. C.; Dozmorov, M. G.

10.1101/549170 — bioinformatics — Posted on 2019-02-13

1614 Kevlar: a mapping-free framework for accurate discovery of de novo variants

Standage, D. S.; Brown, C. T.; Hormozdiari, F.

10.1101/549154 — bioinformatics — Posted on 2019-02-13

1615 96 Eyes: Parallel Fourier Ptychographic Microscopy for high throughput screening

Chan, A. C. S.; Kim, J.; Pan, A.; Xu, H.; Nojima, D.; Hale, C.; Wang, S.; Yang, C.

10.1101/547265 — bioinformatics — Posted on 2019-02-13

1616 Corticostriatal synaptic weight evolution in a two-alternative forced choice task

Vich, C.; Dunovan, K.; Verstynen, T. V.; Rubin, J.

10.1101/549253 — animal behavior and cognition — Posted on 2019-02-13

1617 Unraveling ChR2-driven stochastic Ca2+ dynamics in astrocytes - A call for new interventional paradigms

Moshkforoush, A.; Balachandar, L.; Moncion, C.; Santana, J.; Riera, J.

10.1101/549469 — neuroscience — Posted on 2019-02-13

1618 Assessing the potential impact of Medicaid work requirements on African-Americans via a welfare reform analysis: A systematic review

Hall, G.; Burrowes, S.

10.1101/549493 — scientific communication and education — Posted on 2019-02-13

1619 Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation

Pan, Q.; Feron, R.; Yano, A.; Guyomard, R.; Jouanno, E.; Vigouroux, E.; Wen, M.; Busnel, J.-M.; Bobe, J.; Concordet, J.-P.; Parrinello, H.; Journot, L.; Klopp, C.; Lluch, J.; Roques, C.; Postlethwait, J.; Schartl, M.; Herpin, A.; Guiguen, Y.

10.1101/549527 — evolutionary biology — Posted on 2019-02-13

1620 Detection of classic and cryptic Strongyloides genotypes by deep amplicon sequencing: A preliminary survey of dog and human specimens collected from remote Australian communities

Beknazarova, M.; Barratt, J. L. N.; Bradbury, R. S.; Lane, M.; Whiley, H.; Ross, K.

10.1101/549535 — zoology — Posted on 2019-02-13

1621 Robustness of respiratory rhythm generation across dynamic regimes

Rubin, J.; Smith, J.

10.1101/549444 — neuroscience — Posted on 2019-02-13

1622 Comparative genome analysis of Lactobacillus mudanjiangensis, an understudied member of the Lactobacillus plantarum group

Wuyts, S.; Allonsius, C. N.; Wittouck, S.; Thys, S.; Lievens, B.; Weckx, S.; De Vuyst, L.; Lebeer, S.

10.1101/549451 — microbiology — Posted on 2019-02-13

1623 Impacts of diets fed after weaning on gut microbiota and susceptibility to DSS-induced colitis in mice

Meng, Y.; Li, X.; Chen, S.; Li, F.; Yin, Y.; Liu, J.; Lu, F.; Liu, X.

10.1101/549501 — microbiology — Posted on 2019-02-13

1624 Lewy pathology in Parkinson's disease consists of a crowded organellar, membranous medley

Shahmoradian, S. H.; Lewis, A. J.; Genoud, C.; Graff-Meyer, A.; Hench, J.; Moors, T.; Schweighauser, G.; Wang, J.; Goldie, K. N.; Suetterlin, R.; Castano-Diez, D.; Perez-Navarro, P.; Huisman, E.; Ipsen, S.; Ingrassia, A.; de Gier, Y.; Rozemuller, A. J. M.; Da Paepe, A.; Erny, J.; Staempfli, A.; Hoernschemeyer, J.; Grosserueschkamp, F.; Niedieker, D.; El-Mashtoly, S. F.; Quadri, M.; van IJcken, W. F. J.; Bonifati, V.; Gerwert, K.; Bohrmann, B.; Frank, S.; Britschgi, M.; Stahlberg, H.; van de Berg, W.; Lauer, M. E.

10.1101/137976 — neuroscience — Posted on 2019-02-13

1625 Fenoxaprop-p-ethyl susceptibility and mutation point detection of acetyl-coa carboxylase (ACCase) in different wild oat (Avena fatua L.) populations from China

Zhang, B.; Liu, J.; Chen, X.; Lu, L.

10.1101/549402 — molecular biology — Posted on 2019-02-13

1626 Emergence of multidrug-resistant Mycobacterium simiae: An in vitro study from a regional tuberculosis reference laboratory in Iran

Nasiri, M. J.; Amini, S.; Nikpor, Z.; Arefzadeh, S.; Mosavi, M.; Dabiri, H.; Goudarzi, M.; Goudarzi, H.; Tabarsi, P.; Sarokhalil, D. D.; Fooladi, A. A. I.; Feizabadi, M. M.

10.1101/549428 — microbiology — Posted on 2019-02-13

1627 Urinary glucocorticoids in harbour seal (Phoca vitulina) pups during rehabilitation

Wilson, S. C.; Villanueva, S.; Dmitrieva, L.; Hayes, W.; Smyth, W.

10.1101/549386 — zoology — Posted on 2019-02-13

1628 Thermodynamic Measures of Human Brain Development from Fetal Stage to Adulthood

Tuszynski, J.; Rietman, E.; Taylor, S.; Siegelmann, H.; Cavaglia, M.

10.1101/549360 — neuroscience — Posted on 2019-02-13

1629 Ecological Representations

Golonka, S.; Wilson, A. D.

10.1101/058925 — animal behavior and cognition — Posted on 2019-02-13

1630 Modeling how early passive immunization with broadly neutralizing antibodies elicits lasting control of SHIV infection

Desikan, R.; Raja, R.; Dixit, N. M.

10.1101/548727 — immunology — Posted on 2019-02-13

1631 A null model of the mouse whole-neocortex micro-connectome

Reimann, M. W.; Gevaert, M.; Shi, Y.; Lu, H.; Markram, H.; Muller, E.

10.1101/548735 — neuroscience — Posted on 2019-02-13

1632 The international sinonasal microbiome study (ISMS): a multi centre, international characterization of sinonasal bacterial ecology

Paramasivan, S.; Bassiouni, A.; Shiffer, A.; Dillon, M. R.; Cope, E.; Cooksley, C.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P.; Luong, A.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/548743 — microbiology — Posted on 2019-02-13

1633 Measles vaccine virus RNA in children more than 100 days after vaccination

McMahon, J. L.; Mackay, I. M.; Lambert, S. B.

10.1101/548701 — microbiology — Posted on 2019-02-13

1634 Automated high-throughput heart rate measurement in medaka and zebrafish embryos under physiological conditions

Gierten, J.; Pylatiuk, C.; Hammouda, O. T.; Schock, C.; Stegmaier, J.; Wittbrodt, J.; Gehrig, J.; Loosli, F.

10.1101/548594 — developmental biology — Posted on 2019-02-13

1635 Extracellular Caspase-1 regulates migration of hair follicle stem cells upon wounding

Ghosh, S.; Pincha, N.; Ananthan, A. S.; Kataria, S.; Dey, R.; P, S.; Jamora, C.

10.1101/548529 — cell biology — Posted on 2019-02-13

1636 Reassessment of the basis of cell size control based on analysis of cell-to-cell variability

Facchetti, G.; Knapp, B.; Chang, F.; Howard, M.

10.1101/548545 — cell biology — Posted on 2019-02-13

1637 Dynamic membrane topology in an unassembled membrane protein

Seurig, M.; Ek, M.; Von Heijne, G.; Fluman, N.

10.1101/548537 — biochemistry — Posted on 2019-02-13

1638 Comparative biomechanical characterization of maize brace roots within andbetween plants

Erndwein, L.; Ganji, E.; Killian, M. L.; Sparks, E. E.

10.1101/547794 — plant biology — Posted on 2019-02-13

1639 Repeated treatment with cocaine or methamphetamine increases CRF2 and decreases astrocytic markers in the ventral tegmental area and substantia nigra

Sharpe, A. L.; Trzeciak, M.; Douglas, P.; Beckstead, M. J.

10.1101/548487 — neuroscience — Posted on 2019-02-13

1640 Reducing variability in along-tract analysis with diffusion profile realignment

St-Jean, S.; Chamberland, M.; Viergever, M. A.; Leemans, A.

10.1101/541920 — neuroscience — Posted on 2019-02-13

1641 Convergent seed color adaptation during repeated domestication of an ancient new world grain

Stetter, M. G.; Vidal-Villarejo, M.; Schmid, K. J.

10.1101/547943 — evolutionary biology — Posted on 2019-02-13

1642 Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress

Molinaro, R.; Flick, R.; Philpott, D. J.; Girardin, S. E.

10.1101/547885 — immunology — Posted on 2019-02-13

1643 Multivariate climate change, the climate niche, and the Holocene history of eastern hemlock (Tsuga canadensis)

Shuman, B. N.; Oswald, W. W.; Foster, D. R.

10.1101/548420 — ecology — Posted on 2019-02-13

1644 Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ

Minkin, I.; Medvedev, P.

10.1101/548123 — bioinformatics — Posted on 2019-02-13

1645 Tracking the emergence of location-based spatial representations

Berens, S. C.; Joensen, B. H.; Horner, A. J.

10.1101/547976 — neuroscience — Posted on 2019-02-13

1646 Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dys-regulation of Epithelial-Mesenchymal Transition and subcellular re-localization of Beta-Catenin

Bowler, E.; Smith-Vidal, A.; Lester, A.; Bell, J.; Wang, Z.; Bell, C.; Wang, Y.; Divecha, N.; Skipp, P.; Ewing, R. M.

10.1101/547737 — cancer biology — Posted on 2019-02-13

1647 PTSD Biomarker Database: Deep Dive Meta-database for PTSD Biomarkers, Visualizations, and Analysis Tools

Domingo-Fernandez, D.; Provost, A.; Kodamullil, A. T.; Marin-Llao, J.; Lasseter, H.; Diaz, K.; Daskalakis, N.; Lancashire, L.; Hofmann-Apitius, M.; Haas, M.

10.1101/547901 — bioinformatics — Posted on 2019-02-13

1648 Mesenchymal stromal cell remodeling of a gelatin hydrogel microenvironment defines an artificial hematopoietic stem cell niche

Gilchrist, A. E.; Lee, S.; Hu, Y.; Harley, B.

10.1101/289553 — bioengineering — Posted on 2019-02-13

1649 Work Flows for Cellular Epidemiology, From Conception to Translation

Nathanson, A. D.; Ngo, L.; Garbowski, T.; Srikantha, A.; Wojek, C.; Zeidler, D.; Knothe Tate, M.

10.1101/548412 — physiology — Posted on 2019-02-13

1650 Neural and linguistic differences explain priming and interference during naming

Wei, T.; Schnur, T. T.

10.1101/547745 — neuroscience — Posted on 2019-02-13

1651 MuStARD: Deep Learning for intra- and inter-species scanning of functional genomic patterns

Georgakilas, G. K.; Grioni, A.; Liakos, K. G.; Malanikova, E.; Plessas, F. C.; Alexiou, P.

10.1101/547679 — bioinformatics — Posted on 2019-02-13

1652 Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Glaser, A. K.; Reder, N. P.; Chen, Y.; Yin, C.; Wei, L.; Kang, S.; Barner, L. A.; Xie, W.; McCarty, E. F.; Mao, C.; Halpern, A. R.; Stoltzfus, C. R.; Daniels, J. S.; Gerner, M. Y.; Nicovich, P. R.; Vaughan, J. C.; True, L. D.; Liu, J. T. C.

10.1101/548107 — bioengineering — Posted on 2019-02-13

1653 Adaptive efficient coding of correlated acoustic properties

Lu, K.; Liu, W.; Dutta, K.; Fritz, J. B.; Shamma, S. A.

10.1101/548156 — neuroscience — Posted on 2019-02-13

1654 Reduced competition between tool action neighbors in left hemisphere stroke

Garcea, F.; Stoll, H.; Buxbaum, L.

10.1101/547950 — neuroscience — Posted on 2019-02-13

1655 Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

Adams, M. J.; Howard, D. M.; Luciano, M.; Davies, G. M.; Hill, W. D.; 23andMe Research Team, ; Major Depressive Disorder Working Group of the Psy, ; Smith, D. J.; Deary, I. J.; Porteous, D. J.; McIntosh, A. M.

10.1101/547828 — genetics — Posted on 2019-02-13

1656 Sequencing and Imputation in GWAS: Cost-Effective Strategies to Increase Power and Genomic Coverage Across Diverse Populations

Quick, C.; Anugu, P.; Musani, S.; Weiss, S. T.; Burchard, E. G.; White, M. J.; Keys, K. L.; NHLBI Trans-Omics for Precision Medicine (TOPMed), ; Cucca, F.; Sidore, C.; Boehnke, M.; Fuchsberger, C.

10.1101/548321 — genetics — Posted on 2019-02-13

1657 Theoretical Expression for the Evolution of Genomic Island of Speciation: From Its Birth to Preservation

Sakamoto, T.; Innan, H.

10.1101/545103 — evolutionary biology — Posted on 2019-02-13

1658 The asymmetric chemical structures of two mating pheromones reflect their differential roles in conjugation of Schizosaccharomyces pombe

Seike, T.; Maekawa, H.; Nakamura, T.; Shimoda, C.

10.1101/548586 — cell biology — Posted on 2019-02-13

1659 Investigation of the effect of estradiol and subculturing on the receptor expression within hormone-dependent breast cancer cells

Mallick, A.; Ahmed, S.

10.1101/548271 — cancer biology — Posted on 2019-02-13

1660 MiR-590-5p sensitises pancreatic ductal adenocarcinoma cells by blocking autophagy via targeting ATG3

Yang, L.; Li, F.; He, J.; Liu, S.; Zhang, Y.

10.1101/548610 — cancer biology — Posted on 2019-02-13

1661 MEXCOWalk: Mutual Exclusion and Coverage Based Random Walk to Identify Cancer Modules

Ahmed, R.; Baali, I.; Erten, C.; Hoxha, E.; Kazan, H.

10.1101/547653 — bioinformatics — Posted on 2019-02-13

1662 Silicone oil-induced ocular hypertension in mouse models glaucomatous neurodegeneration and neuroprotection

Zhang, J.; Li, L.; Huang, H.; Webber, H.; Zhuang, P.; Liu, L.; Dalal, R.; Tang, P. H.; Mahajan, V. B.; Sun, Y.; Li, S.; Zhang, M.; Goldberg, J. L.; Hu, Y.

10.1101/547661 — neuroscience — Posted on 2019-02-13

1663 Segmentation-Enhanced CycleGAN

Januszewski, M.; Jain, V.

10.1101/548081 — neuroscience — Posted on 2019-02-13

1664 Gut microbiota requires vagus nerve integrity to promote depression

Siopi, E.; Saha, S.; Moigneu, C.; Bigot, M.; Lledo, P.-M.

10.1101/547778 — neuroscience — Posted on 2019-02-13

1665 MicroRNA-143 plays a protective role in ischemia-induced retinal neovascularization

Wang, J.-H.; Chen, J.; Ling, D.; Tu, L.; Singh, V.; Riaz, M.; Li, F.; Prea, S. M.; He, Z.; Bui, B. V.; Hewitt, A. W.; van Wijngaarden, P.; Dusting, G. J.; Liu, G.-S.

10.1101/548297 — molecular biology — Posted on 2019-02-13

1666 Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data

Nordström, K.; Schmidt, F.; Gasparoni, N.; Salhab, A.; Gasparoni, G.; Kattler, K.; Müller, F.; Ebert, P.; Costa, I. G.; DEEP consortium, ; Pfeifer, N.; Lengauer, T.; Schulz, M. H.; Walter, J.

10.1101/547596 — genomics — Posted on 2019-02-13

1667 Single-cell RNA sequencing of a European and an African lymphoblastoid cell line

Osorio, D.; Yu, X.; Yu, P.; Serpedin, E.; Cai, J. J.

10.1101/548115 — genetics — Posted on 2019-02-13

1668 Drug resistance evolution in HIV in the late 1990s: hard sweeps, soft sweeps, clonal interference and the accumulation of drug resistance mutations

Williams, K.-A.; Pennings, P. S.

10.1101/548198 — evolutionary biology — Posted on 2019-02-13

1669 Vitellogenin expression in the ovaries of adult honeybee workers provides insights into the evolution of reproductive and social traits

Cardoso Junior, C.; Oldroyd, B.; Ronai, I.

10.1101/547760 — evolutionary biology — Posted on 2019-02-13

1670 Decoding and recoding phase behavior of TDP43 reveals that phase separation is not required for splicing function

Schmidt, H. B.; Barreau, A.; Rohatgi, R.

10.1101/548339 — cell biology — Posted on 2019-02-13

1671 A Gelatin Hydrogel to Study Endometrial Angiogenesis and Trophoblast Invasion

Zambuto, S. G.; Clancy, K.; Harley, B.

10.1101/548024 — bioengineering — Posted on 2019-02-13

1672 A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity

Chahwan, R.; Sheppard, E. C.; Rogers, S.; Harmer, N. J.

10.1101/548628 — biochemistry — Posted on 2019-02-13

1673 Control of Shoot Meristem Size by an Aminoacyl tRNA Synthetase, OKI1, in Arabidopsis

Kitagawa, M.; Balkunde, R. S.; Bui, H. T.; Jackson, D. S.

10.1101/548164 — plant biology — Posted on 2019-02-13

1674 Resting-state cross-frequency coupling networks in human electrophysiological recordings

Siebenhuehner, F.; Wang, S. H.; Arnulfo, G.; Nobili, L.; Palva, J. M.; Palva, S.

10.1101/547638 — neuroscience — Posted on 2019-02-13

1675 EPI distortion correction for simultaneous human brain stimulation and imaging at 3T

Oh, H.; Kim, J. H.; Yau, J.

10.1101/547935 — neuroscience — Posted on 2019-02-13

1676 Strain-level differences in gut microbiome composition determine fecal IgA levels and are modifiable by gut microbiota manipulation

Yang, C.; Mogno, I.; Contijoch, E. J.; Borgerding, J. N.; Aggarwala, V.; Li, Z.; Grasset, E. K.; Helmus, D. S.; Dubinsky, M. C.; Mehandru, S.; Cerutti, A.; Faith, J. J.

10.1101/544015 — immunology — Posted on 2019-02-13

1677 Generating High Density, Low Cost Genotype Data in Soybean

Happ, M.; Wang, H.; Graef, G.; Hyten, D.

10.1101/547711 — genomics — Posted on 2019-02-13

1678 Variation in filamentous growth and response to quorum-sensing compounds in environmental isolates of Saccharomyces cerevisiae

Lenhart, B. A.; Meeks, B.; Murphy, H.

10.1101/548099 — genetics — Posted on 2019-02-13

1679 Phylogeographic parallelism: concordance of patterns in closely related species illuminates underlying mechanisms in the historically glaciated Tasmanian landscape

Kreger, K.; Shaban, B.; Wapstra, E.; Burridge, C. P.

10.1101/548446 — evolutionary biology — Posted on 2019-02-13

1680 Temporal resolution of global gene expression and DNA methylation changes in the final phases of reprogramming towards induced pluripotency.

Bartoccetti, M.; Luo, X.; van der Veer, B.; Khoueiry, R.; Janiszewski, A.; Xu, J.; Verfaillie, C.; Pasque, V.; Thienpont, B.; Koh, K. P.

10.1101/547646 — cell biology — Posted on 2019-02-13

1681 Feasibility of using a fully immersive virtual reality system for kinematic data collection

Spitzley, K. A.; Karduna, A. R.

10.1101/547992 — bioengineering — Posted on 2019-02-13

1682 rhizoTrak: A flexible open source Fiji plugin for user-friendly manual annotation of time-series images from minirhizotrons

Moeller, B.; Chen, H.; Schmidt, T.; Zieschank, A.; Patzak, R.; Tuerke, M.; Weigelt, A.; Posch, S.

10.1101/547604 — plant biology — Posted on 2019-02-13

1683 Lotus japonicus symbiosis signaling genes and their role in the establishment of root-associated bacterial and fungal communities

Zgadzaj, R.; Thiergart, T.; Bozsoki, Z.; Garridoo Oter, R.; Radutoiu, S.; Schulze-Lefert, P.

10.1101/547687 — plant biology — Posted on 2019-02-13

1684 Biochemical characterization of the methylmercaptopropionate:cob(I)alamin methyltransferase from Methanosarcina acetivorans

Fu, H.; Goettge, M. N.; Metcalf, W. W.

10.1101/548461 — microbiology — Posted on 2019-02-13

1685 Structure of the Ebola virus nucleoprotein - RNA complex

Kirchdoerfer, R. N.; Saphire, E. O.; Ward, A. B.

10.1101/548313 — biophysics — Posted on 2019-02-13

1686 Differential responses of antioxidants and dehydrin expression in two switchgrass (Panicum virgatum) cultivars contrasting in drought tolerance

Liu, Y.; Hu, G.; Wu, G.; Liu, G.; Huan, H.; Ding, X.; Yan, L.; Li, X.; Zhao, B.; Zhang, X.

10.1101/486308 — plant biology — Posted on 2019-02-12

1687 The dimensionality of biological diversity revisited

Nakamura, G.; Goncalves, L. O.; Duarte, L.

10.1101/508002 — ecology — Posted on 2019-02-12

1688 Interneuronal correlations dynamically adjust to task demands at multiple time-scales

Ben Hadj Hassen, S.; Gaillard, C.; Astrand, E.; Wardak, C.; Ben Hamed, S.

10.1101/547802 — neuroscience — Posted on 2019-02-12

1689 The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand

Pantazis, C.; James, M. H.; Bentzley, B. S.; Aston-Jones, G.

10.1101/547836 — neuroscience — Posted on 2019-02-12

1690 Loss of Shh signaling in the neocortex reveals heterogeneous cell recovery responses from distinct oligodendrocyte populations

Winkler, C. C.; Franco, S. J.

10.1101/547968 — neuroscience — Posted on 2019-02-12

1691 ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing

Frausto, R. F.; Chung, D. D.; Boere, P. M.; Swamy, V. S.; Duong, H. N. V.; Kao, L.; Azimov, R.; Zhang, W.; Carrigan, L.; Wong, D.; Morselli, M.; Zakharevich, M.; Hanser, E. M.; Kassels, A. C.; Kurtz, I.; Pellegrini, M. F.; Aldave, A. J.

10.1101/547927 — cell biology — Posted on 2019-02-12

1692 Direct Visualization of Live Zebrafish Glycan via Single-step Metabolic Labeling with Fluorophore-tagged Nucleotide Sugars

Hong, S.; Sahai-Hernandez, P.; Traver, D.; Wu, P.

10.1101/548016 — biochemistry — Posted on 2019-02-12

1693 Galaxy-Kubernetes integration: scaling bioinformatics workflows in the cloud

Moreno, P.; Pireddu, L.; Roger, P.; Goonasekera, N.; Afgan, E.; van den Beek, M.; He, S.; Larsson, A.; Ruttkies, C.; Schober, D.; Johnson, D.; Rocca-Serra, P.; Weber, R. J. M.; Gruening, B.; Salek, R.; Kale, N.; Perez-Riverol, Y.; Papatheodorou, I.; Spjuth, O.; Neumann, S.

10.1101/488643 — bioinformatics — Posted on 2019-02-12

1694 Robust network inference using response logic

Gross, T.; Wongchenko, M.; Yan, Y.; Bluthgen, N.

10.1101/547216 — systems biology — Posted on 2019-02-12

1695 White matter changes in the perforant path in patients with amyotrophic lateral sclerosis

Mollink, J.; Hiemstra, M.; Miller, K. L.; Huszar, I. N.; Jenkinson, M.; Raaphorst, J.; Wiesmann, M.; Ansorge, O.; Pallebage-Gamarallage, M.; van Cappellen van Walsum, A.-M.

10.1101/547588 — neuroscience — Posted on 2019-02-12

1696 Clinical investigation and genetic analysis of a peripheral sclerocornea pedigree

Zhang, B. N.; Chan, T. C. Y.; Tam, P. O. S.; Liu, Y.; Pang, C. P.; Jhanji, V.; Chen, L. J.; Chu, W. K.

10.1101/547547 — genetics — Posted on 2019-02-12

1697 Earth-Gravity Congruent Motion Benefits Visual Gain For Parabolic Trajectories

Jorges, B.; Lopez-Moliner, J.

10.1101/547497 — neuroscience — Posted on 2019-02-12

1698 Applications of community detection algorithms to large biological datasets

Kanter, I.; Yaari, G.; Kalisky, T.

10.1101/547570 — bioinformatics — Posted on 2019-02-12

1699 Aversive learning strengthens episodic memory in both adolescents and adults

Cohen, A. O.; Matese, N. G.; Filimontseva, A.; Shen, X.; Shi, T. C.; Livne, E.; Hartley, C. A.

10.1101/547331 — animal behavior and cognition — Posted on 2019-02-12

1700 A dataset to explore kinase control of environmental stress responsive transcription

Mace, K.; Krakowiak, J.; El-Samad, H.; Pincus, D.

10.1101/547356 — systems biology — Posted on 2019-02-12

1701 Medusa: software to build and analyze ensembles of genome-scale metabolic network reconstructions

Medlock, G. L.; Papin, J.

10.1101/547174 — systems biology — Posted on 2019-02-12

1702 Neural processing of communication signals: The extent of sender-receiver matching varies across species of Apteronotus

Allen, K. M.; Marsat, G.

10.1101/387324 — neuroscience — Posted on 2019-02-12

1703 Memory quality modulates the effect of aging on memory consolidation during sleep: Reduced maintenance but intact gain

Muehlroth, B.; Sander, M. C.; Fandakova, Y.; Grandy, T. H.; Rasch, B.; Shing, Y. L.; Werkle-Bergner, M.

10.1101/547448 — neuroscience — Posted on 2019-02-12

1704 Theta and Gamma Bands Encode Acoustic Dynamics over Wide-ranging Timescales

Teng, X.; Poeppel, D.

10.1101/547125 — neuroscience — Posted on 2019-02-12

1705 Indirect pathway of caudate tail for choosing good objects in periphery

Amita, H.; Hikosaka, O.

10.1101/547232 — neuroscience — Posted on 2019-02-12

1706 The IL-12 and IL-23-Dependent NK Cell Response is Essential For Protective Immunity Against Secondary Toxoplasma gondii Infection.

Ivanova, D. L.; Mundhenke, T. M.; Gigley, J.

10.1101/547455 — immunology — Posted on 2019-02-12

1707 Assessment of Dried Blood Spots for DNA Methylation Profiling

Walker, R. M.; MacGillivray, L.; McCafferty, S.; Wrobel, N.; Murphy, L.; Kerr, S. M.; Morris, S. W.; Campbell, A.; McIntosh, A. M.; Porteous, D. J.; Evans, K. L.

10.1101/546606 — genomics — Posted on 2019-02-12

1708 Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

Smith, O.; Dunshea, G.; Sinding, M.-H. S.; Fedorov, S.; Germonpre, M.; Bocherens, H.; Gilbert, M. T. P.

10.1101/546820 — genomics — Posted on 2019-02-12

1709 Ecological speciation in European whitefish is driven by a large-gaped predator

Ohlund, G.; Bodin, M.; Nilsson, K. A.; Ohlund, S.-O.; Mobley, K.; Hudson, A. G.; Peedu, M.; Brannstrom, A.; Bartels, P.; Praebel, K.; Hein, C. L.; Johansson, P.; Englund, G.

10.1101/543744 — evolutionary biology — Posted on 2019-02-12

1710 Temporal switching of species roles in a plant-pollinator network

Miele, V.; Ramos-Jiliberto, R.; Vazquez, D. P.

10.1101/543637 — ecology — Posted on 2019-02-12

1711 Pathogenic potential of Hic1 expressing cardiac stromal progenitors

Soliman, H.; Paylor, B.; Scott, W.; Lemos, D.; Chang, C.; Arostegui, M.; Low, M.; Lee, C.; Fiore, D.; Braghetta, P.; Pospichalova, V.; Barkauskas, C. E.; Korinek, V.; Rampazzo, A.; MacLeod, K.; Underhill, T. M.; Rossi, F.

10.1101/544403 — cell biology — Posted on 2019-02-12

1712 Conditional activation of immune-related signatures and prognostic significance: a pan-cancer analysis

Roelands, J.; Hendrickx, W.; Mall, R.; Saad, M.; Halliwill, K.; Zoppoli, G.; Curigliano, G.; Rinchai, D.; Decock, J.; Delogu, L.; Chouchane, L.; Wang, E.; Kuppen, P.; Finetti, P.; Bertucci, F.; Miller, L.; Galon, J.; Marincola, F.; Ceccarelli, M.; Bedognetti, D.

10.1101/546069 — cancer biology — Posted on 2019-02-12

1713 Unsupervised Machine Learning for Analysis of Coexisting Lipid Phases and Domain Growth in Biological Membranes

Lopez, C. A.; Vesselinov, V. V.; Gnanakaran, S.; Alexandrov, B. S.

10.1101/527630 — bioinformatics — Posted on 2019-02-12

1714 CONSENT: Scalable self-correction of long reads with multiple sequence alignment

Morisse, P.; Marchet, C.; Limasset, A.; Lecroq, T.; Lefebvre, A.

10.1101/546630 — bioinformatics — Posted on 2019-02-12

1715 Machine Learning Classification of Attention-Deficit/Hyperactivity Disorder Using Structural MRI Data

Zhang-James, Y.; Helminen, E.; Liu, J.; the ENIGMA-ADHD working group, ; Franke, B.; Hoogman, M.; Faraone, S.

10.1101/546671 — bioinformatics — Posted on 2019-02-12

1716 Surpassing thermodynamic, kinetic, and stability barriers to isomerization catalysis for tagatose biosynthesis

Bober, J. R.; Nair, N.

10.1101/547166 — bioengineering — Posted on 2019-02-12

1717 A mechanism for ligand gated strand displacement in ZTP riboswitch transcription regulation

Strobel, E. J.; Cheng, L.; Berman, K. E.; Carlson, P. D.; Lucks, J. B.

10.1101/521930 — biochemistry — Posted on 2019-02-12

1718 Revealing the ocean metabolome with mass spectrometry

Sogin, E. M.; Puskas, E.; Dubilier, N.; Liebeke, M.

10.1101/528307 — biochemistry — Posted on 2019-02-12

1719 Repressive gene regulation synchronizes development with cellular metabolism

Cassidy, J. J.; Bernasek, S.; Bakker, R.; Giri, R.; Pelaez, N.; Eder, B.; Bobrowska, A.; Bagheri, N.; Amaral, L. A.; Carthew, R. W.

10.1101/548032 — developmental biology — Posted on 2019-02-12

1720 Pupil responses to hidden photoreceptor-specific modulations in movies

Spitschan, M.; Gardasevic, M.; Martial, F.; Lucas, R.; Allen, A.

10.1101/440040 — neuroscience — Posted on 2019-02-12

1721 Improved Representation of Sequence Bloom Trees

Harris, R. S.; Medvedev, P.

10.1101/501452 — bioinformatics — Posted on 2019-02-12

1722 ChIPulate: A comprehensive ChIP-seq simulation pipeline

Datta, V.; Hannenhalli, S. S.; Siddharthan, R.

10.1101/467241 — bioinformatics — Posted on 2019-02-12

1723 Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding

Puljung, M.; Vedovato, N.; Usher, S.; Ashcroft, F. M.

10.1101/402206 — biophysics — Posted on 2019-02-12

1724 Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR

Danks, G.; Galbiati, H.; Raasholm, M.; Torres Cleuren, Y. N.; Valen, E.; Navratilova, P.; Thompson, E. M.

10.1101/353979 — genomics — Posted on 2019-02-12

1725 Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia

Tsai, Y.-W.; Sung, H.-H.; Li, J.-C.; Yeh, C.-Y.; Chen, P.-Y.; Cheng, Y.-J.; Chen, C.-H.; Tsai, Y.-C.; Chien, C.-T.

10.1101/547554 — developmental biology — Posted on 2019-02-12

1726 The making of an olfactory specialist

Auer, T. O.; Khallaf, M. A.; Silbering, A. F.; Zappia, G.; Ellis, K.; Hansson, B.; Jefferis, G. S. X. E.; Caron, S.; Knaden, M.; Benton, R.

10.1101/546507 — neuroscience — Posted on 2019-02-12

1727 lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation

Daneshvar, K.; Ardehali, M. B.; Klein, I. A.; Kratkiewicz, A. J.; Zhou, C.; Mahpour, A.; Cook, B. M.; Li, W.; Pondick, J. V.; Moran, S. P.; Young, R. A.; Kingston, R. E.; Mullen, A. C.

10.1101/547513 — molecular biology — Posted on 2019-02-12

1728 Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the Gβ subunit

Tsai, C.-J.; Marino, J.; Adaixo, R. J.; Pamula, F.; Muehle, J.; Maeda, S.; Flock, T.; Taylor, N. M.; Mohammed, I.; Matile, H.; Dawson, R. J.; Deupi, X.; Stahlberg, H.; Schertler, G. F.

10.1101/547919 — biochemistry — Posted on 2019-02-12

1729 Dynamic architecture of the Escherichia coli structural maintenance of chromosomes (SMC) complex, MukBEF

Arciszewska, L. K.; Rajasekar, K. V.; Tang, M.; Baker, R.; Zawadzka, K.; Koczy, O.; Wagner, F.; Bolla, J. R.; Robinson, C. V.; Sherratt, D. J.

10.1101/547786 — biochemistry — Posted on 2019-02-12

1730 Changes in Ovary Transcriptome and Alternative Splicing at Estrus from Xiang Pigs with Large and Small Litter Size

Zhang, F. P.; Ran, X. Q.

10.1101/547810 — molecular biology — Posted on 2019-02-12

1731 Exercise twice-a-day potentiates skeletal muscle signalling responses associated with mitochondrial biogenesis in humans, which are independent of lowered muscle glycogen content

Andrade-Souza, V. A.; Ghiarone, T.; Sansonio, A.; Silva, K. A. S.; Tomazini, F.; Arcoverde, L.; Fyfe, J.; Perri, E.; Saner, N.; Kuang, J.; Bertuzzi, R.; Leandro, C. G.; Bishop, D. J.; Lima-Silva, A. E.

10.1101/547489 — molecular biology — Posted on 2019-02-12

1732 No single, stable 3D representation can explain pointing biases in a spatial updating task

Vuong, J.; Fitzgibbon, A.; Glennerster, A.

10.1101/390088 — neuroscience — Posted on 2019-02-12

1733 Dissociable Neural Correlates of Uncertainty Underlie Different Exploration Strategies

Tomov, M.; Truong, V.; Hundia, R.; Gershman, S.

10.1101/478131 — neuroscience — Posted on 2019-02-12

1734 Neurons of the inferior olive respond to broad classes of sensory input while subject to homeostatic control

Ju, C.; Bosman, L. W.; Hoogland, T. M.; Velauthapillai, A.; Murugesan, P.; Warnaar, P.; van Genderen, R. M.; Negrello, M.; De Zeeuw, C. I.

10.1101/379149 — neuroscience — Posted on 2019-02-12

1735 Alanine tRNAs translate environment into behavior in Caenorhabditis elegans

Fernandes De Abreu, D. A.; Salinas-Giege, T.; Marechal-Drouard, L.; Remy, J.-J.

10.1101/289629 — evolutionary biology — Posted on 2019-02-12

1736 The effect of spatial variation for predicting aphid epidemics

Damgaard, C.; Bruus, M.; Axelsen, J. A.

10.1101/367953 — ecology — Posted on 2019-02-12

1737 Satiety, Thermosensation and Mechanosensation Regulate a Spontaneous C. elegans Sleep State

Gonzales, D. L.; Zhou, J.; Robinson, J.

10.1101/547075 — neuroscience — Posted on 2019-02-12

1738 A rare variant on a common risk haplotype of HFE causes increased risk of hereditary hemochromatosis

Glazer, A. M.; Bastarache, L.; Hall, L.; Short, L.; Shields, T.; Kroncke, B. M.; Denny, J. C.; Roden, D. M.

10.1101/547471 — genetics — Posted on 2019-02-12

1739 Transposable elements contribute to dynamic genome content in maize

Anderson, S. N.; Stitzer, M. C.; Brohammer, A. B.; Zhou, P.; Noshay, J. M.; Hirsch, C. D.; Ross-Ibarra, J.; Hirsch, C. N.; Springer, N. M.

10.1101/547398 — genomics — Posted on 2019-02-12

1740 Generalizing to generalize: when (and when not) to be compositional in task structure learning

Franklin, N. T.; Frank, M. J.

10.1101/547406 — neuroscience — Posted on 2019-02-12

1741 Ephrin-A5 potentiates netrin-1 axon guidance by enhancing Neogenin availability

Croteau, L.-P.; Kao, T.-J.; Kania, A.

10.1101/547299 — neuroscience — Posted on 2019-02-12

1742 Thermodynamic Measures of Human Brain Developmentfrom Fetal Stage to Adulthood

rietman, e.; taylar, s.; Siegelmann, H.; cavaglia, m.; tuszynski, j.

10.1101/547364 — neuroscience — Posted on 2019-02-12

1743 Ultra-thin fluorocarbon foils optimize multiscale imaging of three-dimensional native and optically cleared specimens

Hoette, K.; Koch, M.; Hof, L.; Tuppi, M.; Moreth, T.; Stelzer, E. H. K.; Pampaloni, F.

10.1101/533844 — cell biology — Posted on 2019-02-12

1744 Novel Methodology to Detect Physical Interaction of Inositol Phospholipid with Potassium Ion Channel Using Luminescence Resonance Energy Transfer

Chin, F.; Cheng, P.-C.

10.1101/546283 — biochemistry — Posted on 2019-02-12

1745 Cell cycle dynamics of human pluripotent stem cells primed for differentiation

Shcherbina, A.; Li, J.; Narayanan, C.; Greenleaf, W.; Kundaje, A.; Chetty, S.

10.1101/546291 — genetics — Posted on 2019-02-12

1746 Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry

Allard, C. A. H.; Opalko, H. E.; Moseley, J. B.

10.1101/547224 — cell biology — Posted on 2019-02-12

1747 Accelerating Dissociative Events in Molecular Dynamics Simulations by Selective Potential Scaling

Deb, I.; Frank, A. T.

10.1101/547307 — biophysics — Posted on 2019-02-12

1748 3D Microstructure of Tendon Collagen Fibrils using Serial Block-Face SEM and a Mechanical Model for Load Transfer

Safa, B. N.; Peloquin, J. M.; Natriello, J. R.; Caplan, J. L.; Elliott, D. M.

10.1101/547281 — bioengineering — Posted on 2019-02-12

1749 Real-time computation of the TMS-induced electric field in a realistic head model

Stenroos, M.; Koponen, L. M.

10.1101/547315 — neuroscience — Posted on 2019-02-12

1750 Systematic Analysis of Metabolic Pathway Distributions of Bacterial Energy Reserves

Wang, L.; Yang, J.; Huang, Y.; Liu, Q.; Xu, Y.; Piao, X.; Wise, M. J.

10.1101/545715 — microbiology — Posted on 2019-02-12

1751 Coinfection of semi-infectious particles can contribute substantially to influenza infection dynamics

Farrell, A.; Brooke, C.; Koelle, K.; Ke, R.

10.1101/547349 — microbiology — Posted on 2019-02-12

1752 Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses

Cuellar-Partida, G.; Lundberg, M.; Kho, P. F.; D'Urso, S.; Gutierrez-Mondragon, L. F.; Hwang, L.-D.

10.1101/518027 — genetics — Posted on 2019-02-12

1753 Generalization of the minimum covariance determinant algorithm for categorical and mixed data types

Beaton, D.; Sunderland, K. M.; ADNI, ; Levine, B.; Mandzia, J.; Masellis, M.; Swartz, R. H.; Troyer, A. K.; ONDRI, ; Binns, M. A.; Abdi, H.; Strother, S. C.

10.1101/333005 — bioinformatics — Posted on 2019-02-12

1754 Machine Learning Methods to Identify Genetic Correlates of Radiation-Associated Contralateral Breast Cancer in the WECARE Study

Lee, S.; Liang, X.; Woods, M.; Reiner, A.; Thomas, D.; Concannon, P.; Bernstein, L.; Lynch, C.; Boice, J.; Deasy, J.; Bernstein, J.; Oh, J. H.

10.1101/547422 — bioinformatics — Posted on 2019-02-12

1755 Intrinsic plasticity of cerebellar Purkinje cells in motor learning circuits

Jang, D. C.; Shim, H. G.; Kim, S. J.

10.1101/513283 — neuroscience — Posted on 2019-02-11

1756 Fan cells in layer 2 of lateral entorhinal cortex are critical for episodic-like memory

Vandrey, B.; Garden, D. L. F.; Ambrozova, V.; McClure, C.; Nolan, M. F.; Ainge, J. A.

10.1101/543777 — neuroscience — Posted on 2019-02-11

1757 FERMI: A novel method for sensitive detection of rare mutations in somatic tissue

Liggett, L. A.; Sharma, A.; De, S.; DeGregori, J.

10.1101/208066 — genetics — Posted on 2019-02-11

1758 Pandoravirus celtis illustrates the microevolution processes at work in the giant Pandoraviridae genomes

LEGENDRE, M.; ALEMPIC, J.-M.; PHILIPPE, N.; LARTIGUE, A.; JEUDY, S.; POIROT, O.; TA, N. T.; NIN, S.; COUTE, Y.; ABERGEL, C.; CLAVERIE, J.-M.

10.1101/500207 — evolutionary biology — Posted on 2019-02-11

1759 Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

Chkhaidze, K.; Heide, T.; Werner, B.; Williams, M. J.; Huang, W.; Caravagna, G.; Graham, T. A.; Sottoriva, A.

10.1101/544536 — bioinformatics — Posted on 2019-02-11

1760 Resourceful mice do not starve: feeding efforts and decision-making process under a restricted unknown food source

Hernandez, M.; Navarro-Castilla, A.; Barja, I.

10.1101/546705 — animal behavior and cognition — Posted on 2019-02-11

1761 Probing Neural Networks for Dynamic Switches of Communication Pathways

Finger, H.; Gast, R.; Gerloff, C.; Engel, A. K.; König, P.

10.1101/523522 — neuroscience — Posted on 2019-02-11

1762 Sound source localization with varying amount of visual information in virtual reality

Ahrens, A.; Lund, K. D.; Marschall, M.; Dau, T.

10.1101/489484 — neuroscience — Posted on 2019-02-11

1763 Disentangling semantic and response learning effects in color-word contingency learning

Geukes, S.; Vorberg, D.; Zwitserlood, P.

10.1101/546689 — neuroscience — Posted on 2019-02-11

1764 When expectations are not met: unraveling the computational mechanisms underlying the effect of expectation on perceptual thresholds

Urgen, B. M.; Boyaci, H.

10.1101/545244 — neuroscience — Posted on 2019-02-11

1765 Adhesive defence mucus secretions in the red triangle slug (Triboniophorus graeffei) can incapacitate adult frogs

Gould, J.; Valdez, J. W.; Upton, R.

10.1101/544775 — animal behavior and cognition — Posted on 2019-02-11

1766 Conditional approach as cooperation in predator inspection: a role for serotonin?

Pimentel, A. F. N.; Carvalho, T. d. S.; Lima, F.; Lima-Maximino, M. G.; Soares, M. C.; Maximino, C.

10.1101/436345 — animal behavior and cognition — Posted on 2019-02-11

1767 Rewiring of Th-memory-associated gene co-expression networks underlie immunotherapy-induced changes in symptom expression in mite-sensitised atopics

Jones, A. C.; Anderson, D.; Troy, N. M.; Mallon, D.; Hartmann, R.; Serralha, M.; Holt, B. J.; Bosco, A.; Holt, P. G.

10.1101/473561 — immunology — Posted on 2019-02-11

1768 Loss of TP73 function contributes to amyotrophic lateral sclerosis pathogenesis

Downie, J. M.; Gibson, S. B.; Tsetsou, S.; Russell, K. L.; Keefe, M. D.; Figueroa, K. P.; Bromberg, M. B.; Murtaugh, C.; Bonkowsky, J. L.; Pulst, S. M.; Jorde, L. B.

10.1101/451419 — genetics — Posted on 2019-02-11

1769 Arenaviridae exoribonuclease presents genomic RNA edition capacity.

Yekwa, E.; Aphibanthammakit, C.; Carnec, X.; Picard, C.; Canard, B.; Baize, S.; Ferron, F.

10.1101/541698 — biochemistry — Posted on 2019-02-11

1770 Unraveling intra- and intersegmental neuronal connectivity between central pattern generating networks in a multi-legged locomotor system

Daun, S.; Mantziaris, C.; Toth, T.; Bueschges, A.; Rosjat, N.

10.1101/453423 — neuroscience — Posted on 2019-02-11

1771 Laboratory Methods Supporting Measles surveillance in Queensland, Australia, 2010-2017

McMahon, J. L.; Northill, J. A.; Finger, M.; Lyon, M.; Lambert, S. B.; Mackay, I. M.

10.1101/472175 — microbiology — Posted on 2019-02-11

1772 Dynamics of gene expression in single root cells of A. thaliana

Jean-Baptiste, K.; McFaline-Figueroa, J. L.; Alexandre, C. M.; Dorrity, M. W.; Saunders, L.; Bubb, K. L.; Trapnell, C.; Fields, S.; Queitsch, C.; Cuperus, J. T.

10.1101/448514 — genetics — Posted on 2019-02-11

1773 Stem cell mitotic drive ensures asymmetric epigenetic inheritance

Ranjan, R.; Snedeker, J.; Chen, X.

10.1101/416446 — developmental biology — Posted on 2019-02-11

1774 Ends and middle: global force balance determines septum location in fission yeast

Le Goff, X.; Comelles, J.; Kervrann, C.; Riveline, D.

10.1101/520007 — cell biology — Posted on 2019-02-11

1775 Basal forebrain GABAergic innervation of olfactory bulb periglomerular interneurons

Sanz Diez, A.; Najac, M.; De Saint Jan, D.

10.1101/216259 — neuroscience — Posted on 2019-02-11

1776 Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

Nalls, M. A.; Blauwendraat, C.; Vallerga, C. L.; Heilbron, K.; Bandres-Ciga, S.; Chang, D.; Tan, M.; Kia, D. A.; Noyce, A. J.; Xue, A.; Bras, J.; Young, E.; von Coelln, R.; Simon-Sanchez, J.; Schulte, C.; Sharma, M.; Krohn, L.; Pihlstrom, L.; Siitonen, A.; Iwaki, H.; Leonard, H.; Faghri, F.; Gibbs, J. R.; Hernandez, D. G.; Scholz, S. W.; Botia, J. A.; Martinez, M.; Corvol, J.-C.; Lesage, S.; Jankovic, J.; Shulman, L. M.; The 23andMe Research Team, ; System Genomics of Parkinson's Disease (SGPD) Consortium, ; Sutherland, M.; Tienari, P.; Majamaa, K.; Toft, M.; Brice, A.; Yang, J.; Gan-Orr, Z

10.1101/388165 — genetics — Posted on 2019-02-11

1777 Randomized lasso associates freshwater lake-system specific bacterial taxa with heterotrophic production through flow cytometry

Rubbens, P.; Schmidt, M. L.; Props, R.; Biddanda, B. A.; Boon, N.; Waegeman, W.; Denef, V. J.

10.1101/392852 — ecology — Posted on 2019-02-11

1778 Combining 3D single molecule localization strategies for reproducible bioimaging

Cabriel, C.; Bourg, N.; Jouchet, P.; Dupuis, G.; Leterrier, C.; Baron, A.; Badet-Denisot, M.-A.; Vauzeilles, B.; Fort, E.; Leveque-Fort, S.

10.1101/385799 — biophysics — Posted on 2019-02-11

1779 Different mechanisms drive the maintenance of polymorphism at loci subject to strong versus weak fluctuating selection

Bertram, J.; Masel, J.

10.1101/164723 — evolutionary biology — Posted on 2019-02-11

1780 Respiratory syncytial virus activates Rab5a to suppress IRF1-dependent IFN-{lambda} production, subverting the antiviral defense of airway epithelial cells

gao, l.; tang, w.; xie, j.; chen, s.; ren, l.; zang, n.; xie, x.; deng, y.; Liu, E.

10.1101/547182 — immunology — Posted on 2019-02-11

1781 Exploring the influence of surface proteins on probiotic activity of Lactobacillus pentosus HC-2 in Litopenaeus vannamei midgut via Label-free quantitative proteomic analysis

Du, Y.; Fang, H.; Liu, M.; Jiang, K.; Wang, M.; Wang, B.; Wang, L.

10.1101/546762 — microbiology — Posted on 2019-02-11

1782 The Human Nickel Microbiome and its relationship to Allergy and Overweight in Women

Lusi, E. A.; Santino, I.; Petrucca, A.; Zollo, V.; Magri, F.; O'Shea, D.; Tammaro, A.

10.1101/546739 — microbiology — Posted on 2019-02-11

1783 Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

Smith, O.; Dunshea, G.; Sinding, M.-H. S.; Fedorov, S.; Germonpre, M.; Bocherens, H.; Gilbert, M. T. P.

10.1101/546820 — genomics — Posted on 2019-02-11

1784 Reclamation is not the primary determinant of soil recovery from oil and gas development in Wyoming sagebrush systems

Rottler, C.; Burke, I. C.; Lauenroth, W. K.

10.1101/546804 — ecology — Posted on 2019-02-11

1785 Environmental specificity and evolution in Drosophila-bacteria symbiosis

Guilhot, R.; Rombaut, A.; Xuereb, A.; Howell, K.; Fellous, S.

10.1101/546838 — evolutionary biology — Posted on 2019-02-11

1786 Predictor species: Improving assessments of rare species occurrence by modelling environmental co-responses

Thompson, P. R.; Fagan, W. F.; Staniczenko, P. P. A.

10.1101/546879 — ecology — Posted on 2019-02-11

1787 Assemblage of Focal Species Recognizers - AFSR: A technique for decreasing false positive rates of acoustic automatic identification in a multiple species context

Campos, I. B.; Landers, T. J.; Lee, K. D.; Lee, W. G.; Friesen, M. R.; Gaskett, A. C.; Ranjard, L.

10.1101/546812 — ecology — Posted on 2019-02-11

1788 High resolution single-cell chromatin 3D modeling reveals coherent chromatin aggregation with varied structures in controlling genome function stability

Meng, L.; Shi, Y.; Wang, C.

10.1101/546572 — biophysics — Posted on 2019-02-11

1789 Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices

Racioppi, C.; Wiechecki, K. A.; Christiaen, L.

10.1101/546945 — developmental biology — Posted on 2019-02-11

1790 Quantifying the impact of genetically regulated expression on complex traits and diseases

Cai, M.; Chen, L.; Liu, J.; Yang, C.

10.1101/546580 — bioinformatics — Posted on 2019-02-11

1791 Where do our graduates go? A toolkit for retrospective and ongoing career outcomes data collection for biomedical PhD students and postdoctoral scholars

Silva, E. A.; Mejia, A. B.; Watkins, E. S.

10.1101/539031 — scientific communication and education — Posted on 2019-02-11

1792 LAB-QA2GO: A free, easy-to-use toolbox for the quality assessment of magnetic resonance imaging data

Vogelbacher, C.; Bopp, M. H. A.; Schuster, V.; Herholz, P.; Sommer, J.; Jansen, A.

10.1101/546564 — neuroscience — Posted on 2019-02-11

1793 Replication competent, 10-segmented influenza viruses as antiviral therapeutics

Haas, G. D.; Harding, A. T.; Heaton, N. S.

10.1101/547059 — microbiology — Posted on 2019-02-11

1794 Machine Learning Classification of Attention-Deficit/Hyperactivity Disorder Using Structural MRI Data

Zhang-James, Y.; Helminen, E.; Liu, J.; the ENIGMA-ADHD working group, ; Franke, B.; Hoogman, M.; Faraone, S.

10.1101/546671 — bioinformatics — Posted on 2019-02-11

1795 SyRI: identification of syntenic and rearranged regions from whole-genome assemblies

Goel, M.; Sun, H.; Jiao, W.-B.; Schneeberger, K.

10.1101/546622 — bioinformatics — Posted on 2019-02-11

1796 Full-length mRNA sequencing reveals principles of poly(A) tail length control

Legnini, I.; Alles, J.; Karaiskos, N.; Ayoub, S.; Rajewsky, N.

10.1101/547034 — systems biology — Posted on 2019-02-11

1797 Multiplex immunofluorescence methods in neurodegenerative diseases

Ehrenberg, A. J.; Morales, D. O.; Tejedor, J. S.; Mulder, J.; Grinberg, L. T.

10.1101/533547 — pathology — Posted on 2019-02-11

1798 Intervention-Induced Changes in Cortical Connectivity and Activity in Severe Chronic Hemiparetic Stroke

Wilkins, K. B.; Dewald, J. P. A.; Yao, J.

10.1101/547083 — neuroscience — Posted on 2019-02-11

1799 Weak modulation of thalamic discharge by basal ganglia output in association with a reaching task

Schwab, B. C.; Kase, D.; Zimnik, A.; Rosenbaum, R.; Rubin, J. E.; Turner, R. S.

10.1101/546598 — neuroscience — Posted on 2019-02-11

1800 Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector

Rocchi, I.; Ericson, C.; Malter, K. E.; Zargar, S.; Eisenstein, F.; Pilhofer, M.; Beyhan, S.; Shikuma, N. J.

10.1101/543298 — microbiology — Posted on 2019-02-11

1801 Oligoribonuclease functions as a diribonucleotidase to bypass a key bottleneck in RNA degradation

Kim, S.-K.; Lormand, J. D.; Weiss, C. A.; Eger, K. A.; Turdiev, H.; Turdiev, A.; Winkler, W. C.; Sondermann, H.; Lee, V. T.

10.1101/546648 — microbiology — Posted on 2019-02-11

1802 Defining mucosal immunity using mass cytometry following experimental human pneumococcal challenge

Jochems, S. P.; de Ruiter, K.; Solorzano, C.; Voskamp, A.; Mitsi, E.; Nikolaou, E.; Carniel, B. F.; Pojar, S.; German, E.; Reine, J.; Soares-Schanoski, A.; Hill, H.; Robinson, R.; Hyder-Wright, A. D.; Weight, C.; Durrenberger, P. F.; Heyderman, R. S.; Gordon, S. B.; Smits, H. H.; Urban, B. C.; Rylance, J.; Collins, A. M.; Wilkie, M. D.; Lazarova, L.; Leong, S. C.; Yazdanbakhsh, M.; Ferreira, D. M.

10.1101/546929 — immunology — Posted on 2019-02-11

1803 Assessment of Dried Blood Spots for DNA Methylation Profiling

Walker, R. M.; MacGillivray, L.; McCafferty, S.; Wrobel, N.; Murphy, L.; Kerr, S. M.; Morris, S. W.; Campbell, A.; McIntosh, A. M.; Porteous, D. J.; Evans, K. L.

10.1101/546606 — genomics — Posted on 2019-02-11

1804 Assessment of kinship detection using RNA-seq data

Vavouri, T.; Blay, N.; Casas Masnou, E.; Galvan-Femenia, I.; Graffelman, J.; de Cid, R.

10.1101/546937 — genomics — Posted on 2019-02-11

1805 Comparative genomics reveals the origin of fungal hyphae and multicellularity

Kiss, E.; Hegedis, B.; Varga, T.; Merenyi, Z.; Koszo, T.; Balint, B.; Prasanna, A. N.; Krizsan, K.; Riquelme, M.; Takeshita, N.; Nagy, L. G.

10.1101/546531 — evolutionary biology — Posted on 2019-02-11

1806 Ordered patterning of the sensory system is susceptible to stochastic features of gene expression

Giri, R.; Papadopoulos, D. K.; Posadas, D. M.; Potluri, H.; Tomancak, P.; Mani, M.; Carthew, R.

10.1101/546911 — developmental biology — Posted on 2019-02-11

1807 Asymmetric post-translational modifications regulate the intracellular distribution of unstimulated STAT3 dimers

Cardoso, B.; Letra-Vilela, R.; Silva-Almeida, C.; Rocha, A. M.; Murtinheira, F.; Branco-Santos, J.; Rodriguez, C.; Martin, V.; Santa-Marta, M.; Herrera, F.

10.1101/546523 — cell biology — Posted on 2019-02-11

1808 The genomic landscape of metastatic castration-resistant prostate cancers using whole genome sequencing reveals multiple distinct genotypes with potential clinical impact

van Dessel, L. F.; van Riet, J.; Smits, M.; Zhu, Y.; Hamberg, P.; van der Heijden, M. S.; Bergman, A. M.; van Oort, I. M.; de Wit, R.; Voest, E. E.; Steeghs, N.; Martens, J. W. M.; Sleijfer, S.; Cuppen, E.; Zwart, W.; van de Werken, H. J. G.; Mehra, N.; Lolkema, M. P.

10.1101/546051 — cancer biology — Posted on 2019-02-11

1809 CXCR3-expressing metastasis-initiating cells induce and exploit a fibroblast niche in the lungs to fuel metastatic colonization

Pein, M.; Insua-Rodriguez, J.; Meier, J.; Hongu, T.; Wiedmann, L.; Essers, M. A. G.; Sinn, H.-P.; Spaich, S.; Sutterlin, M.; Schneeweiss, A.; Trumpp, A.; Oskarsson, T.

10.1101/546952 — cancer biology — Posted on 2019-02-11

1810 The kinetics of nucleotide binding to isolated Chlamydomonas axonemes using UV-TIRF microscopy

Feofilova, M.; Mahamdeh, M. S. S.; Howard, J.

10.1101/547091 — biophysics — Posted on 2019-02-11

1811 CONSENT: Scalable self-correction of long reads with multiple sequence alignment

Morisse, P.; Marchet, C.; Limasset, A.; Lecroq, T.; Lefebvre, A.

10.1101/546630 — bioinformatics — Posted on 2019-02-11

1812 Implementations of the chemical structural and compositional similarity metric in R and Python

Brejnrod, A. D.; Ernst, M.; Dworzynski, P.; Rasmussen, L. B.; Dorrestein, P.; van der Hooft, J.; Arumugam, M.

10.1101/546150 — bioinformatics — Posted on 2019-02-11

1813 Plantarflexor Torque and Work is Positively Correlated with Medial Gastrocnemius Fascicle Length in Healthy Young Adults

Drazan, J. F.; Hullfish, T. J.; Baxter, J. R.

10.1101/547042 — bioengineering — Posted on 2019-02-11

1814 World's Fastest Brain-Computer Interface: Combining EEG2Code with Deep Learning

Nagel, S.; Spüler, M.

10.1101/546986 — neuroscience — Posted on 2019-02-11

1815 Design and evaluation of novel 4-anilinoquinolines and quinazolines as EGFR inhibitors in lung cancer and chordoma

Asquith, C. R. M.; Maffuid, K. A.; Laitinen, T.; Torrice, C. D.; Tizzard, G. J.; Alamillo-Ferrer, C.; Koshlap, K. M.; Crona, D. J.; Zuercher, W.

10.1101/545525 — pharmacology and toxicology — Posted on 2019-02-11

1816 Genome of the parasitoid wasp Diachasma alloeum, an emerging model for ecological speciation and transitions to asexual reproduction

Tvedte, E.; Walden, K. K.; McElroy, K. E.; Werren, J.; Forbes, A. A.; Hood, G. R.; Logsdon, J. M.; Feder, J. L.; Robertson, H. M.

10.1101/545277 — genomics — Posted on 2019-02-11

1817 The crystal structure of the naturally split gp41-1 intein guides the engineering of orthogonal split inteins from a cis-splicing intein

Beyer, H. M.; Mikula, K. M.; Li, M.; Wlodawer, A.; Iwai, H.

10.1101/546465 — biochemistry — Posted on 2019-02-11

1818 Predictive neural processing in adult zebrafish depends on shank3b

Huang, K.-H.; Rupprecht, P.; Schebesta, M.; Serluca, F.; Kitamura, K.; Bouwmeester, T.; Friedrich, R. W.

10.1101/546457 — neuroscience — Posted on 2019-02-11

1819 Nanoscopic Clustering of Neuroligin-3 and Neuroligin-4X Regulates Growth Cone Organization and Size

Gatford, N. J. F.; Deans, M.; Duarte, R. R. R.; Chennell, G.; Raval, P.; Srivastava, D. P.

10.1101/546499 — neuroscience — Posted on 2019-02-11

1820 Optimality of the spontaneous prophage induction rate

Cortes, M. G.; Krog, J.; Balazsi, G.

10.1101/546275 — evolutionary biology — Posted on 2019-02-11

1821 Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size

Gerganova, V.; Floderer, C.; Archetti, A.; Michon, L.; Carlini, L.; Reichler, T.; Manley, S.; Martin, S.

10.1101/546424 — cell biology — Posted on 2019-02-11

1822 Restoration of Direct Corticospinal Communication Across Sites of Spinal Injury

Jayaprakash, N.; Nowak, D.; Eastwood, E.; Krueger, N.; Wang, Z.; Blackmore, M. G.

10.1101/546374 — neuroscience — Posted on 2019-02-11

1823 Future state prediction errors guide active avoidance behavior by adult zebrafish.

Torigoe, M.; Islam, T.; Kakinuma, H.; Fung, C. C. A.; Isomura, T.; Shimazaki, H.; Aoki, T.; Fukai, T.; Okamoto, H.

10.1101/546440 — neuroscience — Posted on 2019-02-11

1824 Extensive loss of cell cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts

Steenwyk, J. L.; Opulente, D.; Kominek, J.; Shen, X.-X.; Zhou, X.; LaBella, A. L.; Bradley, N. P.; Eichman, B. F.; Cadez, N.; Libkind, D.; DeVirgilio, J.; Hulfachor, A. B.; Kurtzman, C. P.; Hittinger, C. T.; Rokas, A.

10.1101/546366 — evolutionary biology — Posted on 2019-02-11

1825 Indexing De Bruijn graphs with minimizers

Marchet, C.; Kerbiriou, M.; Limasset, A.

10.1101/546309 — bioinformatics — Posted on 2019-02-11

1826 Discovering dynamic functional networks in the human neonatal brain with electric source imaging

Mehrkanoon, S.

10.1101/545616 — neuroscience — Posted on 2019-02-11

1827 Comprehensive circular RNA expression profiles in intermuscular fat from lean and obese pigs

Miao, Z.; Zhang, J.; Wang, S.; Wei, P.

10.1101/546390 — molecular biology — Posted on 2019-02-11

1828 Revisiting the evolution and taxonomy of Clostridia, a phylogenomic update

Cruz-Morales, P.; Orellana, C. A.; Moutafis, G.; Moonen, G.; Rincon, G.; Nielsen, L. K.; Marcellin, E.

10.1101/546341 — microbiology — Posted on 2019-02-11

1829 GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors

Sriram, K.; Moyung, K.; Corriden, R.; Carter, H.; Insel, P. A.

10.1101/546481 — bioinformatics — Posted on 2019-02-11

1830 Neuronal memory for language processing

Fitz, H.; Uhlmann, M.; van den Broek, D.; Duarte, R.; Hagoort, P.; Petersson, K. M.

10.1101/546325 — neuroscience — Posted on 2019-02-11

1831 Draft Genome Assembly and Annotation of Red Raspberry Rubus Idaeus

Wight, H.; Zhou, J.; Li, M.; Hannenhalli, S.; Mount, S.; Liu, Z.

10.1101/546135 — genomics — Posted on 2019-02-11

1832 A shared pathway of exosome biogenesis operates at plasma and endosome membranes

Gould, S.; Fordjour, F. K.; Daaboul, G.

10.1101/545228 — cell biology — Posted on 2019-02-11

1833 A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

MacGregor, P.; Gonzalez-Munoz, A. L.; Jobe, F.; Taylor, M. C.; Rust, S.; Sandercock, A. M.; Macleod, O. J. S.; Van Bocxlaer, K.; Francisco, A. F.; D'Hooge, F.; Tiberghien, A.; Barry, C. S.; Howard, P.; Higgins, M. K.; Vaughan, T.; Minter, R.; Carrington, M.

10.1101/547208 — microbiology — Posted on 2019-02-11

1834 The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi

Santos Souza, H. F.; Rocha, S. C.; Damasceno, F. S.; Rapado, L. N.; Pral, E. F.; Marinho, C.; Silber, A. M.

10.1101/546861 — microbiology — Posted on 2019-02-11

1835 Phages associated with horses provide new insights into the dominance of lateral gene transfer in virulent bacteriophages evolution in natural systems

Babenko, V. V.; Golomidova, A. K.; Ivanov, P. A.; Letarova, M. A.; Kulikov, E. E.; Manolov, A. I.; Prokhorov, N. S.; Kostrukova, E. S.; Matyushkina, D. M.; Prilipov, A. G.; Maslov, S.; Belalov, I. S.; Clokie, M. R. J. C.; Letarov, A. V.

10.1101/542787 — evolutionary biology — Posted on 2019-02-11

1836 Climatic Factors in Relation to Diarrhea for Informed Public Health Decision-Making: A Novel Methodological Approach

Ikeda, T.; Kapwata, T.; Behera, S.; Minakawa, N.; Hashizume, M.; Sweijd, N.; Mathee, A.; Wright, C. Y.

10.1101/545046 — epidemiology — Posted on 2019-02-11

1837 Characterizing phenotypic heterogeneity in isogenic bacterial populations using flow cytometry and Raman spectroscopy

Garcia-Timermans, C.; Rubbens, P.; Heyse, J.; Props, R.; Kerckhof, F.-M.; Skirtach, A.; Waegeman, W.; Boon, N.

10.1101/545681 — bioengineering — Posted on 2019-02-11

1838 Opposing signaling pathways regulate morphology in response to temperature in the fungal pathogen Histoplasma capsulatum

Rodriguez, L.; Voorhies, M.; Gilmore, S.; Beyhan, S.; Myint, A.; Sil, A.

10.1101/546853 — microbiology — Posted on 2019-02-11

1839 Whole Genome Detection of Sequence and Structural Polymorphism in Six Diverse Horses

Al Abri, M.; Holl, H. M.; Kalla, S.; Sutter, N.; Brooks, S. A.

10.1101/545111 — genomics — Posted on 2019-02-11

1840 Efficient callus induction and completion of regeneration in kenaf Hibiscus cannabinus

Odahara, M.; Horii, Y.; Kimura, M.; Numata, K.

10.1101/546754 — plant biology — Posted on 2019-02-11

1841 Transcriptome Analysis of juvenile Pacific White Shrimp (Litopenaeus vannamei) with symptom of stunted growth

Gong, B.; Fang, H.; Song, J.; Pang, T.; Peng, C.; Huaiyi Fang, Bin Gong, Jingjing Song, Tingcai Pang, Chunyan Peng,

10.1101/546770 — pathology — Posted on 2019-02-11

1842 The effect of sword bean extract on the relationship between rheumatoid arthritis and periodontitis in mice

Matsumoto, k.; Nakatsuka, Y.; Shirai, K.; Shimizu, S.; Yanase, S.; Abiko, Y.; Furuichi, Y.

10.1101/546788 — immunology — Posted on 2019-02-11

1843 A generic cell surface ligand system for studying cell-cell recognition

Denham, E. M.; Barton, M. I.; Black, S. M.; Bridge, M. J.; de Wet, B.; Paterson, R. L.; van der Merwe, P. A.; Goyette, J.

10.1101/546846 — immunology — Posted on 2019-02-11

1844 Assessment of knowledge, attitudes and practices about antibiotic resistance among medical students in India

Gupta, M. K.; Vohra, C.; Raghav, P.

10.1101/546713 — scientific communication and education — Posted on 2019-02-11

1845 Wildebeest migration in East Africa: Status, threats and conservation measures

Msoffe, F. U.; Ogutu, J. O.; Said, M. Y.; Kifugo, S. C.; de Leeuw, J.; Van Gardingen, P.; Reid, R. S.; Stabach, J. A.; Boone, R.

10.1101/546747 — ecology — Posted on 2019-02-11

1846 Forest fragmentation and impacts of intensive agriculture: responses from functional groups of the tree community

Ribeiro, J. T.; Nunes-Freitas, A. F.; Uzeda, M. C.

10.1101/546796 — ecology — Posted on 2019-02-11

1847 Recombinant expression of osmotin in barley improves stress resistance and food safety during adverse growing conditions

Viktorova, J.; Klcova, B.; Rehorova, K.; Vlcko, T.; Stankova, L.; Jelenova, N.; Cejnar, P.; Kundu, J. K.; Ohnoutkova, L.; Macek, T.

10.1101/546721 — bioengineering — Posted on 2019-02-11

1848 Deep conservation of response element variants regulating plant hormonal responses

Michal, L.-L.; Yahav, C.; Israeli, A.; Efroni, I.

10.1101/544684 — plant biology — Posted on 2019-02-11

1849 Prevalence and Risk Factors for Child Labour and Violence against Child issues in Egypt using Bayesian Geospatial Modelling with Multiple Imputation

Khatab, K.; Raheem, M. A.; Sartorius, B.; Ismail, M.

10.1101/546697 — epidemiology — Posted on 2019-02-11

1850 Oral clade C SHIV challenge models to study pediatric HIV-1 infection by breastmilk transmission

Van Rompay, K. K. A.; Curtis, A. D.; Hudgens, M. G.; Tuck, R.; Choudhary, N.; Dennis, M.; Goswami, R.; Nelson, A. N.; Lifson, J. D.; Ruprecht, R. M.; Shaw, G. M.; Permar, S. R.; De Paris, K.

10.1101/545699 — microbiology — Posted on 2019-02-11

1851 When expectations are not met: unraveling the computational mechanisms underlying the effect of expectation on perceptual thresholds

Urgen, B. M.; Boyaci, H.

10.1101/545244 — neuroscience — Posted on 2019-02-10

1852 Subject sex and partner sex modulate social touch responses across multiple cortical areas

Ebbesen, C. L.; Bobrov, E.; Rao, R. P.; Brecht, M.

10.1101/545434 — neuroscience — Posted on 2019-02-10

1853 Stereotactic system for accurately targeting deep brain structures in awake head-fixed mice

Katz, Y.; Sokoletsky, M.; Lampl, I.

10.1101/539957 — neuroscience — Posted on 2019-02-10

1854 A large self-transmissible plasmid from Nigeria confers resistance to multiple antibacterials without a carrying cost

Monarrez, R.; Braun, M.; Coburn-Flynn, O.; Botelho, J.; Odetoyin, B. W.; Otero-Vera, J. I.; Quartey, N. K.; Peixe, L.; Aboderin, A. O.; Okeke, I. N.

10.1101/545939 — microbiology — Posted on 2019-02-10

1855 Joint inference and alignment of genome structures enables characterization of compartment-independent reorganization across cell types

Rieber, L.; Mahony, S.

10.1101/545194 — bioinformatics — Posted on 2019-02-10

1856 THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images

Hebart, M. N.; Dickter, A. H.; Kidder, A.; Kwok, W. Y.; Corriveau, A.; van Wicklin, C.; Baker, C. I.

10.1101/545954 — neuroscience — Posted on 2019-02-10

1857 Inter-thinker consistency of language activations during abstract thoughts

Berkovich-Ohana, A.; Noy, N.; Harel, M.; Furman-Haran, E.; Arieli, A.; Malach, R.

10.1101/546085 — neuroscience — Posted on 2019-02-10

1858 Probabilistic associative learning suffices for learning the temporal structure of multiple sequences

Martinez, R. H.; Herman, P.; Lansner, A.

10.1101/545871 — neuroscience — Posted on 2019-02-10

1859 The Out of East Asia model versus the African Eve model of modern human origins in light of ancient mtDNA findings

Zhang, Y.; Huang, S.

10.1101/546234 — evolutionary biology — Posted on 2019-02-10

1860 Classifying drugs by their arrhythmogenic risk using machine learning

Sahli Costabal, F.; Seo, K.; Ashley, E.; Kuhl, E.

10.1101/545863 — biophysics — Posted on 2019-02-10

1861 Predicting Pathogenicity of Missense Variants with Weakly Supervised Regression

Cao, Y.; Sun, Y.; Karimi, M.; Chen, H.; Moronfoye, O.; Shen, Y.

10.1101/545913 — bioinformatics — Posted on 2019-02-10

1862 Characterization of Intellectual disability and Autism comorbidity through gene panel sequencing

Aspromonte, M. C.; Bellini, M.; Gasparini, A.; Carraro, M.; Bettella, E.; Polli, R.; Cesca, F.; Bigoni, S.; Boni, S.; Carlet, O.; Negrin, S.; Mammi, I.; Milani, D.; Peron, A.; Sartori, S.; Toldo, I.; Soli, F.; Turolla, L.; Stanzial, F.; Benedicenti, F.; Marino-Buslje, C.; Tosatto, S. C. E.; Murgia, A.; Leonardi, E.

10.1101/545772 — genetics — Posted on 2019-02-10

1863 Soil type shapes unique pathogen communities on nearby populations of a California native bunchgrass

Farner, J. E.; Spear, E. R.; Mordecai, E. A.

10.1101/545632 — ecology — Posted on 2019-02-10

1864 Cusp-artifacts in high order Superresolution Optical Fluctuation Imaging

Yi, X.; Weiss, S.

10.1101/545574 — bioengineering — Posted on 2019-02-10

1865 Volatile organic chemical analyser (eNose) diagnosis of dogs naturally infected with visceral leishmaniasis in Brazil

Staniek, M. E.; Sedda, L.; Gibson, T. D.; de Souza, C. F.; Costa, E. M.; Dillon, R. J.; hamilton, j.

10.1101/545202 — zoology — Posted on 2019-02-10

1866 The Molecular Mass and Isoelectric Point of Plant Proteomes

Mohanta, T.; Khan, A. L.; Hashem, A.; Abd_Allah, E. F.; Al-Harrasi, A.

10.1101/546077 — plant biology — Posted on 2019-02-10

1867 Does Data Cleaning Improve Brain State Classification?

Meisler, S. L.; Ezzyat, Y.; Kahana, M. J.

10.1101/533075 — neuroscience — Posted on 2019-02-10

1868 Metabolome-Wide Mendelian Randomization Analysis of Emotional and Behavioral Responses to Traumatic Stress

Muniz Carvalho, C.; Wendt, F. R.; Stein, D. J.; Stein, M. B.; Gelernter, J.; Belangero, S. I.; Polimanti, R.

10.1101/545442 — genetics — Posted on 2019-02-10

1869 Socioeconomic and Genomic Roots of Verbal Ability

Guo, G.; Lin, M.-J.; Harris, K. M.

10.1101/544411 — genetics — Posted on 2019-02-10

1870 hilldiv: an R package for the integral analysis of diversity based on Hill numbers

Alberdi, A.; Gilbert, M. T. P.

10.1101/545665 — ecology — Posted on 2019-02-10

1871 Measuring individual identity information in animal signals: Overview and performance of available identity metrics

Linhart, P.; Osiejuk, T.; Budka, M.; Salek, M.; Spinka, M.; Policht, R.; Syrova, M.; Blumstein, D. T.

10.1101/546143 — ecology — Posted on 2019-02-10

1872 Shared and dissociable features of apathy and reward system dysfunction in bipolar I disorder and schizophrenia

Kirschner, M.; Cathomas, F.; Manoliu, A.; Habermeyer, B.; Simon, J. J.; Seifritz, E.; Tobler, P. N.; Kaiser, S.

10.1101/546036 — neuroscience — Posted on 2019-02-10

1873 Theta oscillations gate the transmission of reliable sequences in the medial entorhinal cortex

Neru, A.; Assisi, C.

10.1101/545822 — neuroscience — Posted on 2019-02-10

1874 Rich-Club organization: an important determinant of functional outcome after acute ischemic stroke

Schirmer, M. D.; Ktena, S. I.; Nardin, M. J.; Donahue, K. L.; Giese, A.-K.; Etherton, M. R.; Wu, O.; Rost, N. S.

10.1101/545897 — neuroscience — Posted on 2019-02-10

1875 Environmental DNA (eDNA) metabarcoding of pond water as a tool to survey conservation and management priority mammals

Harper, L. R.; Lawson Handley, L.; Carpenter, A. I.; Murray-Dickson, G.; Di Muri, C.; Macgregor, C. J.; Logan, T. W.; Law, A.; Breithaupt, T.; Read, D. S.; McDevitt, A.; Hänfling, B.

10.1101/546218 — molecular biology — Posted on 2019-02-10

1876 Phenome-wide burden of copy number variation in UK Biobank

Aguirre, M.; Rivas, M.; Priest, J.

10.1101/545996 — genomics — Posted on 2019-02-10

1877 KAI2 regulates root and root hair development by modulating auxin distribution

Villaecija Aguilar, J. A.; Hamon-Josse, M.; Carbonnel, S.; Kretschmar, A.; Ljung, K.; Bennett, T.; Gutjahr, C.

10.1101/539734 — plant biology — Posted on 2019-02-10

1878 Optimal use of statistical methods to validate reference gene stability in longitudinal studies

Sundaram, V. K.; Sampathkumar, N. K.; Massaad, C.; Grenier, J.

10.1101/545749 — molecular biology — Posted on 2019-02-10

1879 Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

Taylor, J. A.; Bratton, B. P.; Sichel, S. R.; Blair, K. M.; Jacobs, H. M.; DeMeester, K. E.; Kuru, E.; Gray, J.; Biboy, J.; VanNieuwenhze, M. S.; Vollmer, W.; Grimes, C. L.; Shaevitz, J. W.; Salama, N. R.

10.1101/545517 — microbiology — Posted on 2019-02-10

1880 Hif-1α stabilisation polarises macrophages via cyclooxygenase/prostaglandin E2 in vivo

Lewis, A.; Elks, P. M.

10.1101/536862 — immunology — Posted on 2019-02-10

1881 Warm Temperatures, Cool Sponges: The Effect of Increased Temperatures on the Antarctic Sponge Isodictya sp.

Gonzalez-Aravena, M.; Kenny, N. J.; Osorio, M.; Font, A.; Riesgo, A.; Cardenas, C.

10.1101/416677 — genomics — Posted on 2019-02-10

1882 Minimal effects of proto-Y chromosomes on house fly gene expression in spite of evidence that selection maintains stable polygenic sex determination

Son, J. H.; Kohlbrenner, T.; Heinze, S.; Beukeboom, L.; Bopp, D.; Meisel, R. P.

10.1101/545178 — genomics — Posted on 2019-02-10

1883 Mutation of the ATPase domain of MutS homolog-5 (MSH5) reveals a requirement for a functional MutSγ complex for all crossovers in mammalian meiosis

Milano, C. R.; Holloway, J. K.; Zhang, Y.; Jin, B.; Bergman, A.; Edelmann, W.; Cohen, P. E.

10.1101/546010 — genetics — Posted on 2019-02-10

1884 An alternatively spliced zebrafish jnk1a transcript has an essential and non-redundant role in development of the first heart field derived proximal ventricular chamber.

Santos-Ledo, A.; Washer, S. J.; Dhanaseelan, T.; Chrystal, P.; Papoutsi, T.; Henderson, D.; Chaudhry, B.

10.1101/546184 — developmental biology — Posted on 2019-02-10

1885 Biomarker-based outcome prediction in prostate adenocarcinoma depends on the TMPRSS2-ERG status

Gerke, J. S.; Orth, M. F.; Tolkach, Y.; Romero-Perez, L.; Wehweck, F. S.; Stein, S.; Musa, J.; Knott, M. M. L.; Hoelting, T. L. B.; Li, J.; Sannino, G.; Marchetto, A.; Ohmura, S.; Cidre-Aranaz, F.; Mueller-Nurasyid, M.; Strauch, K.; Stief, C.; Kristiansen, G.; Kirchner, T.; Buchner, A.; Grunewald, T. G. P.

10.1101/546200 — cancer biology — Posted on 2019-02-10

1886 The Piezo channel is used by migrating cells to sense compressive load

Srivastava, N.; Traynor, D.; Kabla, A.; Kay, R.

10.1101/534172 — biophysics — Posted on 2019-02-10

1887 In Silico Genetics: Identification of pathogenic nsSNPs in human STAT3 gene associated with Job's syndrome

Mustafa, M. I.; Abdelmoneim, A. H.; Elfadol, N. M.; Mahmoud, T. A.; Hassan, M. A.

10.1101/545657 — bioinformatics — Posted on 2019-02-10

1888 OrganellarGenomeDRAW (OGDRAW) version 1.3.1: expanded toolkit for the graphical visualization of organellar genomes

Greiner, S.; Lehwark, P.; Bock, R.

10.1101/545509 — bioinformatics — Posted on 2019-02-10

1889 How the initiating ribosome copes with (p)ppGpp to translate mRNAs

Vinogradova, D. S.; Kasatsky, P.; Maksimova, E.; Zegarra, V.; Paleskava, A.; Konevega, A. L.; Milon, P.

10.1101/545970 — biochemistry — Posted on 2019-02-10

1890 Hippocampal Activity Dynamics During Contextual Reward Association in Virtual Reality Place Conditioning

Williams, S. B.; Arriaga, M.; Post, W. W.; Korgaonkar, A. A.; Moron, J. A.; Han, E. B.

10.1101/545608 — neuroscience — Posted on 2019-02-10

1891 Generation of inducible SMARCAL1 knock-down iPSC to model severe Schimke immune-osseous dysplasia reveals a link between replication stress and altered expression of master differentiation genes

Pugliese, G. M.; Salaris, F.; Palermo, V.; Marabitti, V.; Morina, N.; Rosa, A.; Franchitto, A.; Pichierri, P.

10.1101/546093 — cell biology — Posted on 2019-02-10

1892 VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning

Kim, J.; Greenberg, D. E.; Pfifer, R.; Jiang, S.; Xiao, G.; Xie, Y.; Shelburne, S. A.; Koh, A.; Zhan, X.

10.1101/537381 — bioinformatics — Posted on 2019-02-10

1893 Interacting fruit flies synchronize behavior

Klibaite, U.; Shaevitz, J. W.

10.1101/545483 — animal behavior and cognition — Posted on 2019-02-10

1894 Integrating prediction errors at two time scales permits rapid recalibration of speech sound categories

Olasagasti, I.; Giraud, A.-L.

10.1101/479089 — neuroscience — Posted on 2019-02-10

1895 CRISPR-pass: Gene rescue of nonsense mutations using adenine base editors

Lee, C.; Jo, D. H.; Hwang, G.-H.; Yu, J.; Kim, J. H.; Park, S.-e.; Kim, J.-S.; Kim, J. H.; Bae, S.

10.1101/545723 — molecular biology — Posted on 2019-02-10

1896 Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism

Rizzini, L.; Levine, D.; Perelis, M.; Bass, J.; Peek, C.; Pagano, M.

10.1101/545533 — molecular biology — Posted on 2019-02-10

1897 Tissue structure accelerates evolution: premalignant sweeps precede neutral expansion

West, J.; Schenck, R.; Gatenbee, C.; Robertson-Tessi, M.; Anderson, A. R.

10.1101/542019 — cancer biology — Posted on 2019-02-10

1898 Microbiota imprint gut-intrinsic neuronal programming and sympathetic activity

Muller, P. A.; Kerner, Z.; Schneeberger Pane, M.; Mucida, D.

10.1101/545806 — neuroscience — Posted on 2019-02-10

1899 Biogeography and Microscale Diversity Shape the Biosynthetic Potential of Fungus-growing Ant-associated Pseudonocardia

McDonald, B. R.; Chevrette, M. G.; Klassen, J. L.; Horn, H. A.; Caldera, E. J.; Wendt-Pienkowski, E.; Cafaro, M. J.; Ruzzini, A. C.; Van Arnam, E. B.; Weinstock, G. M.; Gerardo, N. M.; Poulsen, M.; Suen, G.; Clardy, J.; Currie, C. R.

10.1101/545640 — microbiology — Posted on 2019-02-10

1900 Systematic Analysis of Metabolic Pathway Distributions of Bacterial Energy Reserves

Wang, L.; Yang, J.; Huang, Y.; Liu, Q.; Xu, Y.; Piao, X.; Wise, M. J.

10.1101/545715 — microbiology — Posted on 2019-02-10

1901 SIMON, an automated machine learning system reveals immune signatures of influenza vaccine responses

Tomic, A.; Tomic, I.; Rosenberg-Hasson, Y.; Dekker, C. L.; Maecker, H. T.; Davis, M. M.

10.1101/545186 — immunology — Posted on 2019-02-10

1902 Prenatal exposure to particulate matter (PM2.5) and low birth weight in a Sri Lankan birth cohort

Tipre, M.; Wickremesinghe, R.; Nandasena, S.; Kasturiratne, A.; Larson, R.; Meleth, S.; Wimalasiri, U.; Smith, T.; Lungu, C.; Sathiakumar, N.

10.1101/461632 — epidemiology — Posted on 2019-02-10

1903 Destin: toolkit for single-cell analysis of chromatin accessibility

Urrutia, E.; Chen, L.; Zhou, H.; Jiang, Y.

10.1101/461905 — bioinformatics — Posted on 2019-02-10

1904 Enhanced TF binding site maps improve regulatory networks learned from accessible chromatin data

Kulkarni, S. R.; Jones, D. M.; Vandepoele, K.

10.1101/545780 — bioinformatics — Posted on 2019-02-10

1905 Differential Principal Components Reveal Patterns of Differentiation in Case/Control Studies

Lengerich, B.; Xing, E. P.

10.1101/545798 — bioinformatics — Posted on 2019-02-10

1906 A non-enzymatic function associated with a putative histone demethylase licenses epigenetic inheritance

Raiymbek, G.; An, S.; Khurana, N.; Gopinath, S.; Trievel, R.; Cho, U.-s.; Ragunathan, K.

10.1101/545814 — biochemistry — Posted on 2019-02-10

1907 The architect of virus assembly: the portal protein complex nucleates procapsid assembly in bacteriophage P22

Motwani, T.; Teschke, C.

10.1101/545707 — biochemistry — Posted on 2019-02-10

1908 Screening for genes that accelerate the epigenetic ageing clock in humans reveals a role for the H3K36 methyltransferase NSD1

Martin-Herranz, D. E.; Aref-Eshghi, E.; Bonder, M. J.; Stubbs, T. M.; Stegle, O.; Sadikovic, B.; Reik, W.; Thornton, J. M.

10.1101/545830 — genomics — Posted on 2019-02-10

1909 Comparative analysis of corrected tiger genome provides clues to their neuronal evolution

Mittal, P.; Jaiswal, S. K.; Vijay, N.; Saxena, R.; Sharma, V. K.

10.1101/544809 — genomics — Posted on 2019-02-10

1910 Adapting in larger numbers can increase the vulnerability of Escherichia coli populations to environmental changes

Chavhan, Y.; Karve, S.; Dey, S.

10.1101/546119 — evolutionary biology — Posted on 2019-02-10

1911 An imaging method to measure conformational changes of voltage sensors of endogenous ion channels in tissue

Thapa, P.; Stewart, R.; Sepela, R. J.; Vivas, O.; Parajuli, L. K.; Lillya, M.; Fletcher-Taylor, S.; Cohen, B. E.; Zito, K.; Sack, J. T.

10.1101/541805 — biophysics — Posted on 2019-02-10

1912 InterLig: a fast and accurate software for ligand-based virtual screening

Mirabello, C.; Wallner, B.

10.1101/544874 — bioinformatics — Posted on 2019-02-10

1913 Species limits in butterflies (Lepidoptera: Nymphalidae): Reconciling classical taxonomy with the multispecies coalescent

Matos-Maravi, P.; Wahlberg, N.; Antonelli, A.; Penz, C.

10.1101/451039 — evolutionary biology — Posted on 2019-02-10

1914 WITER: A powerful method for the estimation of cancer-driver genes using a weighted iterative regression accurately modelling background mutation rate

Jiang, L.; Zheng, J.; Kwan, J.; Dai, S.; Li, C.; Li, M. J.; Yu, B.; TO, K. F.; Sham, P.; Zhu, Y.; Li, M.

10.1101/437061 — bioinformatics — Posted on 2019-02-10

1915 Maternal Circulating MiRNAs That Predict Infant FASD Outcomes Influence Placental Maturation

Tseng, A. M.; Mahnke, A. H.; Wells, A. B.; Salem, N. A.; Allan, A. M.; Roberts, V. H. J.; Newman, N.; Walter, N. A. R.; Kroenke, C. D.; Grant, K. A.; Akison, L. K.; Moritz, K. M.; Chambers, C. D.; Miranda, R. C.

10.1101/409854 — developmental biology — Posted on 2019-02-10

1916 Sequence effects on size, shape, and structural heterogeneity in Intrinsically Disordered Proteins

Baul, U.; Chakraborty, D.; Mugnai, M. L.; Straub, J. E.; Thirumalai, D.

10.1101/427476 — biophysics — Posted on 2019-02-10

1917 Switching on the light: using metagenomic shotgun sequencing to characterize the intestinal microbiome of Atlantic cod

Riiser, E. S.; Haverkamp, T. H. A.; Varadharajan, S.; Borgan, O.; Jakobsen, K. S.; Jentoft, S.; Star, B.

10.1101/545889 — microbiology — Posted on 2019-02-10

1918 Socru: Typing of genome level order and orientation in bacteria

Page, A. J.; Langridge, G.

10.1101/543702 — bioinformatics — Posted on 2019-02-10

1919 Multiplexed CRISPR-Cas9 based genome editing of Rhodosporidium toruloides

Otoupal, P. B.; Ito, M.; Arkin, A. P.; Magnuson, J. K.; Gladden, J. M.; Skerker, J. M.

10.1101/545426 — synthetic biology — Posted on 2019-02-10

1920 Collateral development and arteriogenesis in hindlimbs of domestic swine after ligation of arterial inflow

Patel, N. S.; Gao, Y.; Aravind, S.; Fugelstad, M.; Casale, G.; Pipinos, I. I.; Carlson, M. A.

10.1101/491928 — physiology — Posted on 2019-02-09

1921 Membrane compartmentalization of mycobacterial peptidoglycan synthesis

Garcia-Heredia, A.; Puffal, J.; Judd, J.; Gray, T. A.; Morita, Y. S.; Siegrist, M. S.

10.1101/544338 — microbiology — Posted on 2019-02-09

1922 gFACs: Filtering, analysis, and conversion to unify genome annotations across alignment and gene prediction frameworks.

Caballero, M.; Wegrzyn, J.

10.1101/402396 — bioinformatics — Posted on 2019-02-09

1923 Adhesive defence mucus secretions in the red triangle slug (Triboniophorus graeffei) can incapacitate adult frogs

Gould, J.; Valdez, J. W.; Upton, R.

10.1101/544775 — animal behavior and cognition — Posted on 2019-02-09

1924 Dynamical structure of cortical taste responses revealed by precisely-timed optogenetic perturbation

Mukherjee, N.; Wachutka, J.; Katz, D. B.

10.1101/486043 — neuroscience — Posted on 2019-02-09

1925 Heart Rate n-Variability (HRnV): A Novel Representation of Beat-to-Beat Variation in Electrocardiogram

Liu, N.; Guo, D.; Koh, Z. X.; Ho, A. F. W.; Ong, M. E. H.

10.1101/449504 — bioengineering — Posted on 2019-02-09

1926 Why not record from every channel with a CMOS scanning probe?

Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; David, F.; Fiath, R.; Frazao, J.; Geerts, J. P.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Lopez, C. M.; Maris, E.; Marques-Smith, A.; Marton, G.; McNaughton, B. L.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.

10.1101/275818 — neuroscience — Posted on 2019-02-09

1927 BEES: Bayesian Ensemble Estimation from SAS

Bowerman, S.; Curtis, J. E.; Clayton, J.; Brookes, E. H.; Wereszczynski, J.

10.1101/400168 — biophysics — Posted on 2019-02-09

1928 Dynamical model of the CLC-2 ion channel exhibits a two-step gating mechanism

McKiernan, K. A.; Koster, A. K.; Maduke, M.; Pande, V. S.

10.1101/228163 — biophysics — Posted on 2019-02-09

1929 Translation factor mRNA granules direct protein synthetic capacity to regions of polarized growth

Pizzinga, M.; Bates, C.; Lui, J.; Forte, G.; Morales-Polanco, F.; Linney, E.; Knotkova, B.; Wilson, B.; Solari, C. A.; Berchowitz, L. E.; Portela, P.; Ashe, M. P.

10.1101/447680 — cell biology — Posted on 2019-02-09

1930 Adult-born neurons inhibit developmentally-born neurons in the dentate gyrus

Cahill, S. P.; Martinovic, A.; Cole, J. D.; Snyder, J. S.

10.1101/545673 — neuroscience — Posted on 2019-02-09

1931 Exercise-induced enhancement of synaptic functiontriggered by the inverse BAR protein, Mtss1L.

Chatzi, C.; Zhang, Y.; Hendricks, W. D.; Chen, Y.; Schnell, E.; Goodman, R. H.; Westbrook, G. L.

10.1101/545582 — neuroscience — Posted on 2019-02-09

1932 Dynamic Erasure of Random X-Chromosome Inactivation during iPSC Reprogramming

Janiszewski, A.; Talon, I.; Song, J.; De Geest, N.; To, S. K.; Bervoets, G.; Marine, J.-C.; Rambow, F.; Pasque, V.

10.1101/545558 — developmental biology — Posted on 2019-02-09

1933 TAF1-gene editing impairs Purkinje cell morphology and function

Udaiyappan, J.; Yu, J.; Moutal, A.; Batchelor, S. N.; Anandhan, A.; Khanna, R.; Nelson, M. A.

10.1101/545491 — neuroscience — Posted on 2019-02-09

1934 Microtubules form by progressively faster tubulin accretion, not by nucleation-elongation

Rice, L.; Moritz, M.; Agard, D. A.

10.1101/545236 — cell biology — Posted on 2019-02-09

1935 Unscrambling Fluorophore Blinking for Comprehensive Cluster Detection via PALM

Rossboth, B. K.; Platzer, R.; Sevcsik, E.; Baumgart, F.; Stockinger, H.; Schuetz, G. J.; Huppa, J. B.; Brameshuber, M.

10.1101/545152 — biophysics — Posted on 2019-02-09

1936 Epigenetic regulation of DNA repair mediated by the histone methyltransferase DOT1L

Alvarez, N. S.

10.1101/544981 — molecular biology — Posted on 2019-02-09

1937 Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals

Zhao, B.; Wu, Q.; Ye, Y.; Guo, J.; Zheng, X.; Yang, X.; Yan, L.; Liu, Q.-R.; Hyde, T. M.; Wei, L.; Huang, Y.

10.1101/506758 — genomics — Posted on 2019-02-09

1938 C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

Sowamber, R.; Chehade, R.; Bitar, M.; Dodds, L.; Milea, A.; Slomovitz, B.; Shaw, P.; George, S. H.

10.1101/528885 — cancer biology — Posted on 2019-02-09

1939 Evidence against preserved syntactic comprehension in healthy aging

Poulisse, C.; Wheeldon, L.; Segaert, K.

10.1101/299883 — neuroscience — Posted on 2019-02-09

1940 Sustaining attention for a prolonged period of time increases temporal variability in cortical responses

Reteig, L. C.; van den Brink, R. L.; Prinssen, S.; Cohen, M. X.; Slagter, H. A.

10.1101/501544 — neuroscience — Posted on 2019-02-09

1941 Scaling computational genomics to millions of individuals with GPUs

Taylor-weiner, A.; Aguet, F.; Haradhvala, N.; Gosai, S.; Anand, S.; Kim, J.; Ardlie, K.; Van Allen, E.; Getz, G.

10.1101/470138 — genomics — Posted on 2019-02-09

1942 Horizontal transfer of prokaryotic cytolethal distending toxin B genes to eukaryotes

Verster, K. I.; Wisecaver, J. H.; Duncan, R. P.; Karageorgi, M.; Gloss, A. D.; Armstrong, E.; Price, D. K.; Menon, A. R.; Ali, Z. M.; Whiteman, N. K.

10.1101/544197 — evolutionary biology — Posted on 2019-02-09

1943 The impact of the "World's 25 Most Endangered Primates" list on scientific publications and media

Kerhoas, D.; Acerbi, A.; Webber, A.; McCabe, G.; Mittermeier, R.; Schwitzer, C.

10.1101/541706 — scientific communication and education — Posted on 2019-02-09

1944 Mnemonic introspection in macaques is dependent on dorsolateral prefrontal cortex but not orbitofrontal cortex

Kwok, S. C.; Cai, Y.; Buckley, M. J.

10.1101/381293 — neuroscience — Posted on 2019-02-09

1945 Emergence of Directional Actomyosin Flows from Active Matter Vibrations

Vogel, S. K.; Woelfer, C.; Ramirez, D. A.; Flassig, R. J.; Sundmacher, K.; Schwille, P.

10.1101/394700 — biophysics — Posted on 2019-02-09

1946 Poly-Enrich: Count-based Methods for Gene Set Enrichment Testing with Genomic Regions

Lee, C. T.; Cavalcante, R. G.; Lee, C.; Qin, T.; Patil, S.; Wang, S.; Tsai, Z. T.; Boyle, A. P.; Sartor, M. A.

10.1101/488734 — bioinformatics — Posted on 2019-02-09

1947 Spatial transcriptomics and in silico random pooling identify novel markers of vulnerable and resistant dopamine neurons

Aguila, J.; Cheng, S.; Kee, N.; Cao, M.; Deng, Q.; Hedlund, E.

10.1101/334417 — neuroscience — Posted on 2019-02-08

1948 Mapping axon conduction delays in vivo from microstructural MRI

Drakesmith, M.; Jones, D. K.

10.1101/503763 — neuroscience — Posted on 2019-02-08

1949 Redefining the medicago sativa alphapartitivirus genome sequences

Bejerman, N.; Debat, H.; Trucco, V.; de Breuil, S.; Lenardon, S.; Giolitti, F.

10.1101/529610 — microbiology — Posted on 2019-02-08

1950 Spatial eco-evolutionary feedbacks mediate coexistence inprey-predator systems

Colombo, E. H.; Martinez-Garcia, R.; Lopez, C.; Hernandez-Garcia, E.

10.1101/543934 — ecology — Posted on 2019-02-08

1951 SGK1.1 activation causes early seizure termination via effects on M-current

Armas-Capote, N.; Maglio, L. E.; Perez-Atencio, L.; Martin-Batista, E.; Reboreda, A.; Barios, J. A.; Hernandez, G.; Alvarez de la Rosa, D.; Lamas, J. A.; Barrio, L. C.; Giraldez, T.

10.1101/520775 — neuroscience — Posted on 2019-02-08

1952 The neural dynamics of novel scene imagery

Barry, D. N.; Barnes, G. R.; Clark, I. A.; Maguire, E. A.

10.1101/429274 — neuroscience — Posted on 2019-02-08

1953 ChIPulate: A comprehensive ChIP-seq simulation pipeline

Datta, V.; Hannenhalli, S. S.; Siddharthan, R.

10.1101/467241 — bioinformatics — Posted on 2019-02-08

1954 Disrupted brain structural connectivity in Pediatric Bipolar Disorder with psychosis

Fernandes, H. M.; Cabral, J.; Van Hartevelt, T. J.; Lord, L.-D.; Gleesborg, C.; Moller, A.; Deco, G.; Whybrow, P. C.; Petrovic, P.; James, A. C.; Kringelbach, M. L.

10.1101/241091 — neuroscience — Posted on 2019-02-08

1955 Probing host-anaerobe interactions in innovative human gut cellular models

Anonye, B. O.; Hassall, J.; Patient, J.; Detamornrat, U.; Aladdad, A. M.; Schüller, S.; Rose, F. R. A. J.; Unnikrishnan, M.

10.1101/269035 — microbiology — Posted on 2019-02-08

1956 Network analysis of ChIP-seq data by VULCAN identifies GRHL2 as a key co-regulator of ERa in luminal breast cancer

Holding, A. N.; Giorgi, F. M.; Donnelly, A.; Cullen, A. E.; Nagarajan, S.; Selth, L. A.; Markowetz, F.

10.1101/266908 — cancer biology — Posted on 2019-02-08

1957 Stable multi-level social structure is maintained by habitat geometry in a wild bird population

Farine, D. R.; Sheldon, B. C.

10.1101/085944 — animal behavior and cognition — Posted on 2019-02-08

1958 Modelling Subject Variability in the Spatial and Temporal Characteristics of Functional Modes

Harrison, S. J.; Bijsterbosch, J. D.; Segerdahl, A. R.; Fitzgibbon, S. P.; Duff, E.; Smith, S. M.; Woolrich, M. W.

10.1101/544817 — neuroscience — Posted on 2019-02-08

1959 Electrophysiological correlates of state transition prediction errors

Shahnazian, D.; Ribas-Fernandes, J. J. F.; Holroyd, C. B.

10.1101/544551 — neuroscience — Posted on 2019-02-08

1960 Influence of Mismarking Fiducial Locations on EEG Source Estimation

Shirazi, S. Y.; Huang, H. J.

10.1101/544288 — neuroscience — Posted on 2019-02-08

1961 Age and sex-dependent patterns of gut microbial diversity in human adults

de la Cuesta-Zuluaga, J.; Kelley, S. T.; Chen, Y.; Esobar, J. S.; Mueller, N. T.; Ley, R. E.; McDonald, D.; Huang, S.; Swafford, A. D.; Knight, R.; Thackray, V.

10.1101/544270 — microbiology — Posted on 2019-02-08

1962 Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

Nath, A. P.; Ritchie, S. C.; Grinberg, N. F.; Tang, H. H.; Huang, Q. Q.; Teo, S. M.; Ahola-Olli, A. V.; Würtz, P.; Havulinna, A. S.; Aalto, K.; Pitkänen, N.; Lehtimäki, T.; Kähönen, M.; Lyytikäinen, L.-P.; Raitoharju, E.; Seppälä, I.; Sarin, A.-P.; Ripatti, S.; Palotie, A.; Perola, M.; Viikari, J. S.; Jalkanen, S.; Maksimow, M.; Salmi, M.; Wallace, C.; Raitakari, O. T.; Salomaa, V.; Abraham, G.; Kettunen, J.; Inouye, M.

10.1101/544445 — genomics — Posted on 2019-02-08

1963 A 50-year series of mark-recapture data of large-sized brown trout (Salmo trutta) from Lake Mjosa, Norway

Moe, S. J.; Nater, C. R.; Rustadbakken, A.; Vollestad, L. A.; Lund, E.; Qvenild, T.; Hegge, O.; Aass, P.

10.1101/544825 — ecology — Posted on 2019-02-08

1964 Homotypic and heterotypic trans-assembly of human Rab-family small GTPases in reconstituted membrane tethering

Segawa, K.; Tamura, N.; Mima, J.

10.1101/544379 — cell biology — Posted on 2019-02-08

1965 Chasing the full free energy landscape of neuroreceptor/ligand unbinding by metadynamics simulations

Capelli, R.; Bochicchio, A.; Piccini, G.; Casasnovas, R.; Carloni, P.; Parrinello, M.

10.1101/544577 — biophysics — Posted on 2019-02-08

1966 Chloroplast cold-avoidance response in Marchantia polymorpha occurs independently of changes in endogenous phototropin expression

Fujii, Y.; Ogasawara, Y.; Tamura, S.; Kodama, Y.

10.1101/544361 — plant biology — Posted on 2019-02-08

1967 Auditory prediction errors and auditory white matter microstructure as predictors of psychotic experiences in healthy individuals

Randeniya, R.; Oestreich, L.; Garrido, M.

10.1101/544452 — neuroscience — Posted on 2019-02-08

1968 Comparative genome analysis of 12 Shigella sonnei strains: virulence, resistance, and their interactions

Zhu, Z.; Wang, L.; Gu, F.; Li, Y.; Zhang, H.; Chen, Y.; Shi, J.; Ma, P.; Gu, B.

10.1101/544387 — microbiology — Posted on 2019-02-08

1969 Isolates from colonic spirochaetosis in humans show high genomic divergence and carry potential pathogenic features but are not detected by 16S amplicon sequencing using standard primers for the human microbiota

Thorell, K.; Inganäs, L.; Backhans, A.; Agreus, L.; Öst, A.; Walker, M.; Talley, N. J.; Kjellström, L.; Andreasson, A.; Engstrand, L.

10.1101/544502 — microbiology — Posted on 2019-02-08

1970 Renal Localization of Plasmodium vivax and Zoonotic Monkey Parasite Plasmodium knowlesi in Malaria Associated Acute Kidney Injury

Acharya, P.; Pramanik, A.; Kaur, C.; Sinha, K.; Dinda, A.; Sankar, J.; Bagga, A.; Agarwal, S.; Sinha, A.; Singh, G.

10.1101/544726 — microbiology — Posted on 2019-02-08

1971 XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures

Ellwanger, K.; Arnold, C.; Briese, S.; Kienes, I.; Pfannstiel, J.; Kufer, T. A.

10.1101/545400 — immunology — Posted on 2019-02-08

1972 Genetic, epigenetic and pharmacological influences modulating tissue specific regulation of the cannabinoid receptor -1 (CB1) gene; implications for cannabinoid pharmacogenetics.

Hay, E. A.; Cowie, P. D.; McEwan, A. R.; Wilson, D.; Ross, R.; Barrett, P.; Pertwee, R. G.; MacKenzie, A.

10.1101/544585 — genetics — Posted on 2019-02-08

1973 Microclimate predicts frost-hardiness of alpine Arabidopsis thaliana populations better than altitude because the microclimate effect increases with altitude

Lampei, C.; Wunder, J.; Wilhalm, T.; Schmid, K. J.

10.1101/544791 — evolutionary biology — Posted on 2019-02-08

1974 Estimating cause- and size- specific mortality hazard rates using mark-recapture-recovery data

Nater, C. R.; Vindenes, Y.; Aass, P.; Cole, D.; Langangen, O.; Moe, J.; Rustadbakken, A.; Turek, D.; Vollestad, L. A.; Ergon, T.

10.1101/544742 — ecology — Posted on 2019-02-08

1975 Assaying how the success of phagocytosis depends on the mechanics of a large viscoelastic target

Davis-Fields, M.; Bakhtiari, L.; Kovach, K.; Gordon, V.

10.1101/545004 — biophysics — Posted on 2019-02-08

1976 Object Detection Networks and Augmented Reality for Cellular Detection in Fluorescence Microscopy Acquisition and Analysis.

Waithe, D.; Brown, J. M.; Reglinski, K.; Diez-Sevilla, I.; Roberts, D.; Eggeling, C.

10.1101/544833 — bioinformatics — Posted on 2019-02-08

1977 Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

Chkhaidze, K.; Heide, T.; Werner, B.; Williams, M. J.; Huang, W.; Caravagna, G.; Graham, T. A.; Sottoriva, A.

10.1101/544536 — bioinformatics — Posted on 2019-02-08

1978 Oscillating-flow Thermal Gradient PCR

Kopparthy, V. L.; Crews, N. D.

10.1101/544908 — bioengineering — Posted on 2019-02-08

1979 An Objective Technology-based Assessment of Arm and Hand Sensorimotor Disability in Neurological Disorders

Kanzler, C. M.; Rinderknecht, M. D.; Schwarz, A.; Lamers, I.; Gagnon, C.; Held, J.; Feys, P.; Luft, A. R.; Gassert, R.; Lambercy, O.

10.1101/544601 — neuroscience — Posted on 2019-02-08

1980 A global to local genomics analysis of Clostridioides difficile ST1/RT027 identifies cryptic transmission events in a northern Arizona healthcare network

Williamson, C. H. D.; Stone, N.; Nunnally, A. E.; Hornstra, H.; Wagner, D. M.; Roe, C. C.; Vazquez, A. J.; Nandurkar, N.; Vinocur, J.; Terriquez, J.; Gillece, J.; Travis, J.; Lemmer, D.; Keim, P.; Sahl, J. W.

10.1101/544890 — genomics — Posted on 2019-02-08

1981 Morphological deconvolution of beta-lactam polyspecificity in E. coli

Godinez, W. J.; Chan, H.; Hossain, I.; Li, C.; Ranjitkar, S.; Rasper, D.; Simmons, R. L.; Zhang, X.; Feng, B. Y.

10.1101/545335 — systems biology — Posted on 2019-02-08

1982 Neural organization of speech production: A lesion-based study of error patterns in connected speech

Stark, B. C.; Basilakos, A.; Hickok, G.; Rorden, C.; Bonilha, L.; Fridriksson, J.

10.1101/544841 — neuroscience — Posted on 2019-02-08

1983 Parcellation of the cortex using Surface-based Melbourne Children's Regional Infant Brain atlases (M-CRIB-S)

Adamson, C.; Alexander, B.; Ball, G.; Beare, R.; Chong, J.; Spittle, A.; Doyle, L.; Anderson, P.; Seal, M.; Thompson, D.

10.1101/544304 — neuroscience — Posted on 2019-02-08

1984 Autologous micrograft accelerates endogenous wound healing response via ERK-induced cell migration

Balli, M.; Vitali, F.; Janiszewski, A.; Caluwe, E.; Cortes-Calabuig, A.; Duelen, R.; Ronzoni, F.; Bellazzi, R.; Luttun, A.; Cusella De Angelis, M. G.; Ceccarelli, G.; Lluis, F.; Sampaolesi, M.

10.1101/545376 — molecular biology — Posted on 2019-02-08

1985 Marine-freshwater prokaryotic transitions require extensive changes in the proteome

Cabello-Yeves, P. J.; Rodriguez-Valera, F.

10.1101/544619 — microbiology — Posted on 2019-02-08

1986 Membrane compartmentalization of mycobacterial peptidoglycan synthesis

Garcia-Heredia, A.; Puffal, J.; Julius Judd, J.; Gray, T. A.; Morita, Y. S.; Siegrist, S.

10.1101/544338 — microbiology — Posted on 2019-02-08

1987 netNMF-sc: Leveraging gene-gene interactions for imputation and dimensionality reduction in single-cell expression analysis

Elyanow, R.; Dumitrascu, B.; Engelhardt, B. E.; Raphael, B. J.

10.1101/544346 — genomics — Posted on 2019-02-08

1988 Metabolic Energy Sensing by Mammalian CLC Anion/Proton Exchangers

Grieschat, M.; Langschwager, K.; Guzman, R. E.; Fahlke, C.; Alekov, A. K.

10.1101/545368 — cell biology — Posted on 2019-02-08

1989 Adhesive defence mucus secretions in the red triangle slug (Triboniophorus graeffei) can incapacitate adult frogs

Gould, J.; Valdez, J. W.; Upton, R.

10.1101/544775 — animal behavior and cognition — Posted on 2019-02-08

1990 BRAFV600E Expression in Mouse Neuroglial Progenitors Increase Neuronal Excitability, Cause Appearance of Balloon-like cells, Neuronal Mislocalization, and Inflammatory Immune response.

Goz, R. U.; Silas, A.; Buzel, S.; LoTurco, J. J.

10.1101/544973 — neuroscience — Posted on 2019-02-08

1991 Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images using a Convolutional Neural Network Scheme

Malla, C. U. P.; Valdes-Hernandez, M. d. C.; Rachmadi, F.; Komura, T.

10.1101/544858 — neuroscience — Posted on 2019-02-08

1992 Potential link between selection for high GC content and repair of double strand breaks in prokaryotic genomes

Weissman, J. L.; Fagan, W. F.; Johnson, P. L. F.

10.1101/544924 — microbiology — Posted on 2019-02-08

1993 The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

Deng, L.; Spencer, B. L.; Holmes, J. A.; Mu, R.; Rego, S.; Weston, T. A.; Hu, Y.; Sanches, G. F.; Yoon, S.; Park, N.; Nagao, P. E.; Jenkinson, H. F.; Thornton, J. A.; Seun, K. S.; Nobbs, A. H.; Doran, K. S.

10.1101/544395 — microbiology — Posted on 2019-02-08

1994 In planta chromatin immunoprecipitation in Zymoseptoria tritici reveals chromatin-based regulation of putative effector gene expression

Soyer, J. L.; Grandaubert, J.; Haueisen, J.; Schotanus, K.; Holtgrewe Stukenbrock, E.

10.1101/544627 — microbiology — Posted on 2019-02-08

1995 Characterization of Peripheral Blood Mononuclear Cells Gene Expression Profiles of Pediatric Staphylococcus aureus Persistent and Non-Carriers Using a Targeted Assay

Israelsson, E.; Chaussabel, D.; Fischer, R. S.; Moore, H. C.; Robinson, D. A.; Essigmann, H. T.; Brown, E. L.

10.1101/544494 — immunology — Posted on 2019-02-08

1996 Intrinsic control of muscle attachment sites matching

Carayon, A.; Bataille, L.; Lebreton, G.; Dubois, L.; Pelletier, A.; Carrier, Y.; Wystrach, A.; Vincent, A.; Frendo, J.-L.

10.1101/544569 — developmental biology — Posted on 2019-02-08

1997 The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

Ahmed, S. M.; Ramani, P. D.; Wong, S. Q. R.; Zhao, X.; Ivanyi-Nagy, R.; Leong, T. C.; Chua, C.; Li, Z.; Hentze, H.; Tan, I. B.; Yan, J.; DasGupta, R.; Droge, P.

10.1101/544320 — cancer biology — Posted on 2019-02-08

1998 Updated MS2PIP web server delivers fast and accurate MS2 peak intensity prediction for multiple fragmentation methods, instruments and labeling techniques

Gabriels, R.; Martens, L.; Degroeve, S.

10.1101/544965 — bioinformatics — Posted on 2019-02-08

1999 NMR Methods for Quantitative Isotopomer Rates in Real-Time Metabolism of Cells

Reed, M. A.; Roberts, J.; Gierth, P.; Kupce, E.; Guenther, U. L.

10.1101/544759 — biochemistry — Posted on 2019-02-08

2000 Drying enhances signal intensity for global GC-MS metabolomics.

Liebeke, M.; Puskas, E.

10.1101/544916 — biochemistry — Posted on 2019-02-08

2001 Physiological and Evolutionary Implications of Tetrameric Photosystem I in Cyanobacteria

Li, M.; CALTEAU, A.; Semchonok, D. A.; Witt, T. A.; Nguyen, J. T.; Sassoon, N.; Boekema, E. J.; Whitelegge, J.; Gugger, M.; Bruce, B.

10.1101/544353 — evolutionary biology — Posted on 2019-02-08

2002 A compilation of and typology for abundance-, phylogenetic- and functional-based diversity metrics

Scheiner, S. M.

10.1101/530782 — ecology — Posted on 2019-02-08

2003 Pubertal Testosterone Correlates with Adolescent Impatience and Dorsal Striatal Activity

Laube, C.; Lorenz, R.; van den Bos, W.

10.1101/543710 — neuroscience — Posted on 2019-02-08

2004 Development of a quantitative PCR assay for the detection and enumeration of a potentially ciguatoxin-producing dinoflagellate, Gambierdiscus lapillus (Gonyaulacales, Dinophyceae)

Kretzschmar, A. L.; Verma, A.; Kohli, G.; Murray, S.

10.1101/544247 — molecular biology — Posted on 2019-02-08

2005 Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency

Ariyasu, D.; Kubo, E.; Higa, D.; Shibata, S.; Takaoka, Y.; Sugimoto, M.; Imaizumi, K.; Hasegawa, T.; Araki, K.

10.1101/545384 — genetics — Posted on 2019-02-08

2006 Fan cells in layer 2 of lateral entorhinal cortex are critical for episodic-like memory

Vandrey, B.; Garden, D. L. F.; Ambrozova, V.; McClure, C.; Nolan, M. F.; Ainge, J. A.

10.1101/543777 — neuroscience — Posted on 2019-02-08

2007 Percentage of Foveal versus Total Macular Geographic Atrophy as a Predictor of Visual Acuity in Age-related Macular Degeneration

Bagheri, S.; Lains, I.; Silverman, R.; Kim, I.; Eliott, D.; Silva, R.; Miller, J.; Husain, D.; Miller, J.; Saad, L.; Vavvas, D.

10.1101/544254 — neuroscience — Posted on 2019-02-08

2008 Temporal switching of species roles in a plant-pollinator network

Miele, V.; Ramos-Jiliberto, R.; Vasquez, D. P.

10.1101/543637 — ecology — Posted on 2019-02-08

2009 Highly sensitive in situ proteomics with cleavable fluorescent tyramide reveals human neuronal heterogeneity

Liao, R.; Mondal, M.; Nazaroff, C. D.; Mastroeni, D.; Coleman, P. D.; Guo, J.

10.1101/539106 — systems biology — Posted on 2019-02-08

2010 Abnormalities in Proinsulin Processing in Islets from Individuals with Longstanding T1D

Sims, E. K.; Nyalwidhe, J.; Syed, F.; Bahnson, H. T.; Haataja, L.; Speake, C.; Morris, M.; Mirmira, R. G.; Nadler, J.; Mastracci, T. L.; Arvan, P.; Greenbaum, C. J.; Evans-Molina, C.

10.1101/542027 — pathology — Posted on 2019-02-08

2011 Using extreme gradient boosting (XGBoost) to evaluate the importance of a suite of environmental variables and to predict recruitment of young-of-the-year spotted seatrout in Florida

Herdter, E.

10.1101/543181 — ecology — Posted on 2019-02-08

2012 scGEApp: a Matlab app for feature selection on single-cell RNA sequencing data

Cai, J. J.

10.1101/544163 — bioinformatics — Posted on 2019-02-08

2013 Optimal biochemical information processing at criticality

Stanoev, A.; Nandan, A. P.; Koseska, A.

10.1101/543348 — systems biology — Posted on 2019-02-08

2014 Respiratory gas levels interact to control ventilatory motor patterns in isolated locust ganglia

Talal, S.; Ayali, A.; Gefen, E.

10.1101/543793 — neuroscience — Posted on 2019-02-08

2015 The MarR-type regulator MalR is involved in stress-responsive cell envelope remodeling in Corynebacterium glutamicum

Huennefeld, M.; Persicke, M.; Kalinowski, J.; Frunzke, J.

10.1101/544056 — microbiology — Posted on 2019-02-08

2016 Allele-specific transcript abundance: A pilot study in healthy centenarians

Tindale, L. C.; Thiessen, N.; Leach, S.; Brooks-Wilson, A. R.

10.1101/533398 — genetics — Posted on 2019-02-08

2017 Ecological speciation in European whitefish is driven by a large-gaped predator

Ohlund, G.; Bodin, M.; Nilsson, K. A.; Ohlund, S.-O.; Mobley, K.; Hudson, A. G.; Peedu, M.; Brannstrom, A.; Bartels, P.; Praebel, K.; Hein, C. L.; Johansson, P.; Englund, G.

10.1101/543744 — evolutionary biology — Posted on 2019-02-08

2018 Ionomycin Ameliorates Hypophosphatasia via Rescuing Alkaline Phosphatase Deficiency-mediated L-type Ca2+ Channel Internalization in Mesenchymal Stem Cells

Jin, Y.; Li, B.; He, X.; Dong, Z.; Xuan, K.; Sun, W.; Gao, L.; Liu, S.; Liu, W.; Hu, C.; Zhao, Y.; Shi, S.

10.1101/545418 — cell biology — Posted on 2019-02-08

2019 A unified rheological model for cells and cellularised materials

Bonfanti, A.; Fouchard, J.; Khalilgharibi, N.; Charras, G.; Kabla, A.

10.1101/543330 — biophysics — Posted on 2019-02-08

2020 Whole Brain Polarity Regime Dynamics are Significantly Disrupted in Schizophrenia and Correlate Strongly with Network Connectivity Measures

Miller, R.; Pearlson, G.; Calhoun, V.

10.1101/543751 — neuroscience — Posted on 2019-02-08

2021 The FACTS model of speech motor control: fusing state estimation and task-based control

Parrell, B.; Ramanarayanan, V.; Nagarajan, S.; Houde, J.

10.1101/543728 — neuroscience — Posted on 2019-02-08

2022 Neural Field Models for Latent State Inference: Application to Large-Scale Neuronal Recordings

Rule, M. E.; Schnoerr, D.; Hennig, M. H.; Sanguinetti, G.

10.1101/543769 — neuroscience — Posted on 2019-02-08

2023 A Type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity

Chou-Zheng, L.; Hatoum-Aslan, A.

10.1101/545285 — microbiology — Posted on 2019-02-08

2024 Maternal RhD heterozygous genotype is associated with male biased secondary sex ratio

Kankova, S.; Flegr, J.; Toman, J.; Calda, P.

10.1101/543629 — evolutionary biology — Posted on 2019-02-08

2025 Adverse effects of Bacillus thuringiensis bioinsecticide on non-target Drosophila species

Babin, A.; Nawrot-Esposito, M.-P.; Gallet, A.; Gatti, J.-L.; Poirie, M.

10.1101/541847 — ecology — Posted on 2019-02-08

2026 Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes

Zubcevic, L.; Hsu, A. L.; Borgnia, M. J.; Lee, S.-Y.

10.1101/545293 — biophysics — Posted on 2019-02-08

2027 MDiNE: A model to estimate differential co-occurrence networks in microbiome studies

McGregor, K.; Labbe, A.; Greenwood, C. M.

10.1101/544122 — bioinformatics — Posted on 2019-02-08

2028 Cellular structure image classification with small targeted training samples

Wang, D.; Lu, Z.; Xu, Y.; Wang, Z.; Li, C.; Santella, A.; Bao, Z.

10.1101/544130 — bioinformatics — Posted on 2019-02-08

2029 Induction of microbial oxidative stress as a new strategy to enhance the enzymatic degradation of organic micropollutants in wastewater

Bains, A.; Perez-Garcia, O.; Lear, G.; Greenwood, D.; Swift, S.; Middleditch, M.; Kolodziej, E.; Singhal, N.

10.1101/544205 — bioengineering — Posted on 2019-02-08

2030 Increase in weighting of vision vs. proprioception associated with force field adaptation

Sexton, B. M.; Liu, Y.; Block, H. J.

10.1101/544189 — neuroscience — Posted on 2019-02-08

2031 Distinct roles for the Anterior Temporal Lobe and Angular Gyrus in the spatio-temporal cortical semantic network

Farahibozorg, S.-R.; Henson, R. N.; Woollams, A. M.; Hauk, O.

10.1101/544114 — neuroscience — Posted on 2019-02-08

2032 Maladaptive striatal plasticity and abnormal reward-learning in cervical dystonia

Gilbertson, T.; Humphries, M.; Steele, J. D.

10.1101/543678 — neuroscience — Posted on 2019-02-08

2033 Transition scale-spaces: A computational theory for the discretized entorhinal cortex

Waniek, N.

10.1101/543801 — neuroscience — Posted on 2019-02-08

2034 Insular cortex projections to nucleus accumbens core mediate social approach to stressed juvenile rats

Rogers-Carter, M. M.; Djerdjaj, A.; Gribbons, K. B.; Varela, J.; Christianson, J. P.

10.1101/544221 — neuroscience — Posted on 2019-02-08

2035 Chemical-genetic profiling reveals cross-resistance and collateral sensitivity between antimicrobial peptides

Kintses, B.; Jangir, P. K.; Fekete, G.; Szamel, M.; Mehi, O.; Spohn, R.; Daruka, L.; Martins, A.; Hosseinnia, A.; Gagarinova, A.; Kim, S.; Phanse, S.; Csörgö, B.; Györkei, A.; Ari, E.; Lazar, V.; Farago, A.; Bodai, L.; Nagy, I.; Babu, M.; Pal, C.; Papp, B.

10.1101/542548 — microbiology — Posted on 2019-02-08

2036 Regulation of sexual differentiation is linked to invasion in malaria parasites

Josling, G. A.; Venezia, J.; Orchard, L.; Russell, T. J.; Painter, H. J.; Llinas, M.

10.1101/533877 — microbiology — Posted on 2019-02-08

2037 Designing synthetic bacterial consortia for landfill leachate treatment based on community matrices and regression tree analysis

Hardo, G.; Karunakaran, E.; Couto, N.; Beckerman, A.; Pandhal, J.

10.1101/543694 — microbiology — Posted on 2019-02-08

2038 Helicobacter pylori Senses Bleach as a Chemoattractant Using a Cytosolic Chemoreceptor.

Perkins, A.; Tudorica, D. A.; Amieva, M. R.; Remington, S. J.; Guillemin, K. J.

10.1101/544239 — microbiology — Posted on 2019-02-08

2039 Single-cell profiling of tumor-reactive CD4+ T-cells reveals unexpected transcriptomic diversity

Magen, A.; Nie, J.; Ciucci, T.; Tamoutounour, S.; Zhao, Y.; Mehta, M.; Tran, B.; McGavern, D. B.; Hannenhalli, S.; Bosselut, R.

10.1101/543199 — immunology — Posted on 2019-02-08

2040 8-OxoG in GC-rich Sp1 binding sites enhances gene transcription during adipose tissue development in juvenile mice

Park, J. W.; Han, Y. I.; Kim, T. M.; Yeom, S. C.; Kang, J.; Park, J.

10.1101/538967 — genomics — Posted on 2019-02-08

2041 Compound-V formations in shorebird flocks

Corcoran, A. J.; Hedrick, T. L.

10.1101/545301 — evolutionary biology — Posted on 2019-02-08

2042 The role of mutational spectrum in the selection against mutator alleles

Couce, A.; Tenaillon, O.

10.1101/544031 — evolutionary biology — Posted on 2019-02-08

2043 Parasitology, Poverty and Prevention: is there any relationship between the three P? Is it possible to eradicate Parasitic diseases without eliminating Poverty?

Tshima, G. K.; Mulumba, P. M.

10.1101/544007 — ecology — Posted on 2019-02-08

2044 pH controlled histone acetylation amplifies melanocyte differentiation program downstream of MITF

Natarajan, V.; Raja, D. A.; Gotherwal, V.; Subramaniam, Y. J.; Sultan, F.; Vats, A.; Singh, A.; Sivasubbu, S.; Gokhale, R. S.

10.1101/545392 — cell biology — Posted on 2019-02-08

2045 Asymmetric Tug-of-War leads to Cooperative Transport of a Cargo by Multiple Kinesins

Tjioe, M.; Shukla, S.; Vaidya, R. M.; Troitskaia, A.; Bookwalter, C.; Trybus, K. M.; Chemla, Y. R.; Selvin, P. R.

10.1101/544080 — biophysics — Posted on 2019-02-08

2046 Identifying Drug Sensitivity Subnetworks with NETPHLIX

Kim, Y.-A.; Sarto Basso, R.; Wojtowicz, D.; Hochbaum, D. S.; Vandin, F.; Przytycka, T. M.

10.1101/543876 — bioinformatics — Posted on 2019-02-08

2047 GEMME: a simple and fast global epistatic model predicting mutational effects

Laine, E.; Karami, Y.; Carbone, A.

10.1101/543587 — bioinformatics — Posted on 2019-02-08

2048 Measurement and self-operating computer of the leukocyte continuum as a fixed space-time continuum in inflammation

Nonomura, Y.

10.1101/543611 — bioinformatics — Posted on 2019-02-08

2049 Computational Insights Into Avidity of Polymeric Multivalent Binders

Zumbro, E.; Witten, J.; Alexander-Katz, A.

10.1101/545012 — bioengineering — Posted on 2019-02-08

2050 Microbial biogeography and ecology of the mouth and implications for periodontal diseases

Proctor, D.; Shelef, K.; Gonzalez, A.; Long, C.; Dethlefsen, L.; Burns, A.; Loomer, P.; Armitage, G.; Ryder, M.; Millman, M.; Knight, R.; Holmes, S.; Relman, D. A.

10.1101/541052 — ecology — Posted on 2019-02-08

2051 Development of a fixed list of descriptors for the qualitative behavioural assessment of shelter dogs

Arena, L.; Wemelsfelder, F.; Messori, S.; Ferri, N.; Barnard, S.

10.1101/545020 — animal behavior and cognition — Posted on 2019-02-08

2052 Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

Grandjean, J.; Canella, C.; Anckaerts, C.; Ayrancı, G.; Bougacha, S.; Bienert, T.; Buehlmann, D.; Coletta, L.; Gallino, D.; Gass, N.; Garin, C. M.; Nadkarni, N. A.; Hübner, N.; Karatas, M.; Komaki, Y.; Kreitz, S.; Mandino, F.; Mechling, A. E.; Sato, C.; Sauer, K.; Shah, D.; Strobelt, S.; Takata, N.; Wank, I.; Wu, T.; Yahata, N.; Yeow, L. Y.; Yee, Y.; Aoki, I.; Chakravarty, M. M.; Chang, W.-T.; Dhenain, M.; von Elverfeldt, D.; Harsan, L.-A.; Hess, A.; Jiang, T.; Keliris, G. A.; Lerch, J. P.; Okano, H.; Rudin, M.; Sartorius, A.; Van der Linden, A.; Verhoye, M.; Weber-Fahr, W.; Wenderoth, N.; Ze

10.1101/541060 — neuroscience — Posted on 2019-02-08

2053 Unraveling Diagnostic Biomarkers of Schizophrenia through Structure-Revealing Fusion of Multi-Modal Neuroimaging Data

Acar, E.; Schenker, C.; Levin-Schwartz, Y.; Calhoun, V.; Adali, T.

10.1101/543603 — neuroscience — Posted on 2019-02-08

2054 Attention updates the perceived position of moving objects

Nakayama, R.; Holcombe, A. O.

10.1101/543215 — neuroscience — Posted on 2019-02-08

2055 Rhodopsin-based voltage imaging tools for use in excitable cells of Caenorhabditis elegans

Azimi Hashemi, N.; Bergs, A. C.; Scheiwe, R.; Steuer Costa, W.; Liewald, J. F.; Gottschalk, A.

10.1101/544429 — neuroscience — Posted on 2019-02-08

2056 RapidAIM: A culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs

Li, L.; Ning, Z.; Zhang, X.; Mayne, J.; Cheng, K.; Stintzi, A.; Figeys, D.

10.1101/543256 — microbiology — Posted on 2019-02-08

2057 Segregostat: A novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria

Sassi, H.; Nguyen, T. M.; Telek, S.; Gosset, G.; Grunberger, A.; Delvigne, F.

10.1101/542704 — microbiology — Posted on 2019-02-08

2058 A genetically-encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling

Prole, D. L.; Taylor, C. W.

10.1101/544700 — cell biology — Posted on 2019-02-08

2059 Self-Attention based model for de-novo antibiotic resistant gene classification with enhanced reliability for out of distribution data detection

Hamid, M. N.; Friedberg, I.

10.1101/543272 — bioinformatics — Posted on 2019-02-08

2060 SwiftOrtho: a Fast, Memory-Efficient, Multiple Genome Orthology Classifier

Hu, X.; Friedberg, I.

10.1101/543223 — bioinformatics — Posted on 2019-02-08

2061 hicap: in silico serotyping of the Haemophilus influenzae capsule locus

Watts, S. C.; Holt, K. E.

10.1101/543454 — bioinformatics — Posted on 2019-02-08

2062 A NMF-based approach to discover overlooked differentially expressed gene regions from single-cell RNA-seq data

Matsumoto, H.; Hayashi, T.; Ozaki, H.; Tsuyuzaki, K.; Umeda, M.; Iida, T.; Nakamura, M.; Okano, H.; Nikaido, I.

10.1101/543447 — bioinformatics — Posted on 2019-02-08

2063 Exploring DCAF15 for reprogrammable targeted protein degradation

Coomar, S.; Gillingham, D. G.

10.1101/542506 — biochemistry — Posted on 2019-02-08

2064 The impact of the "World's 25 Most Endangered Primates" list on scientific publications and media

Kerhoas, D.; Acerbi, A.; Webber, A.; McCabe, G.; Mittermeier, R.; Schwitzer, C.

10.1101/541706 — scientific communication and education — Posted on 2019-02-08

2065 Where do our graduates go? A toolkit for retrospective and ongoing career outcomes data collection for biomedical PhD students and postdoctoral scholars

Silva, E. A.; Meja, A. B.; Watkins, E. S.

10.1101/539031 — scientific communication and education — Posted on 2019-02-08

2066 State or trait? MRS-measured GABA and Glutamate concentrations are not modulated by task demand and do not robustly predict task performance

Talsma, L. J.; Van Loon, A.; Scholte, S.; Slagter, H. A.

10.1101/543140 — neuroscience — Posted on 2019-02-08

2067 Long-term vegetation change in species-rich Nardus grasslands of central Germany caused by eutrophication, recovery from acidification and management change

Peppler-Lisbach, C.; Stanik, N.; Könitz, N.; Rosenthal, G.

10.1101/543512 — ecology — Posted on 2019-02-08

2068 When does spatial diversification usefully maximise the durability of crop disease resistance?

Watkinson-Powell, B.; Gilligan, C. A.; Cunniffe, N. J.

10.1101/540013 — epidemiology — Posted on 2019-02-08

2069 High prevalence of precocious menarche in Puerto Barrios, Guatemala

Torres-Gonzalez, E.; Lopez, G.; Trabert, B.; Lou, H.; Guerra, S. P.; Orozco, A.; Garland, L.; Florez-Vargas, O.; Castillo, M.; Argueta, V.; Gharzouzi, E.; Dean, M.; Orozco, R.

10.1101/543090 — epidemiology — Posted on 2019-02-08

2070 Descriptive epidemiology of energy expenditure in the UK: Findings from the National Diet and Nutrition Survey 2008 to 2015

Brage, S.; Lindsay, T.; Venables, M.; Wijndaele, K.; Westgate, K.; Collins, D.; Bluck, L.; Wareham, N.; Page, P.

10.1101/542613 — epidemiology — Posted on 2019-02-08

2071 Patient satisfaction with nursing care in Ethiopia: A systematic review and meta-analysis

Mulugeta, H.; Wagnew, F.; Dessie, G.; Biresaw, H.; Habtewold, T. D.

10.1101/544783 — epidemiology — Posted on 2019-02-08

2072 Socio-spatial heterogeneity in participation in mass dog vaccination campaigns, Arequipa, Peru

Castillo-Neyra, R.; Toledo, A.; Arevalo-Nieto, C.; MacDonald, H.; De la Puente-Leon, M.; Naquira-Velarde, C.; Paz-Soldan, V. A.; Buttenheim, A. M.; Levy, M. Z.

10.1101/542878 — epidemiology — Posted on 2019-02-08

2073 Impact of Prior Cancer on Outcomes in Nasopharyngeal Carcinoma

Zhou, H.; Zhang, Y.; Liu, J.; Fang, W.; Yang, Y.; Hong, S.; Chen, G.; Zhao, S.; Shen, J.; Xian, W.; Zhang, Z.; Chen, X.; Zhao, H.; Huang, Y.; Zhang, L.

10.1101/542126 — epidemiology — Posted on 2019-02-08

2074 Opportunities for improved surveillance and control of infectious diseases from age-specific case data

Rodriguez-Barraquer, I.; Salje, H.; Cummings, D. A.

10.1101/545319 — epidemiology — Posted on 2019-02-08

2075 Improving Proteinuria Screening with Mailed Smartphone Urinalysis Testing in Previously Unscreened Patients with Hypertension: a Randomized Controlled Trial

Leddy, J.; Green, J.; Yule, C.; Molecavage, J.; Coresh, J.; Chang, A. R.

10.1101/536995 — clinical trials — Posted on 2019-02-08

2076 Using genetic instruments to estimate interactions in Mendelian Randomization studies

North, T.-L.; Davies, N. M.; Harrison, S.; Carter, A. R.; Hemani, G.; Sanderson, E.; Tilling, K.; Howe, L.

10.1101/544734 — epidemiology — Posted on 2019-02-08

2077 Using hospital network-based surveillance for antimicrobial resistance as a more robust alternative to self-reporting

Donker, T.; Smieszek, T.; Henderson, K. L.; Walker, T. M.; Hope, R.; Johnson, A. P.; Woodford, N.; Crook, D. W.; Peto, T. E. A.; Walker, S.; Robotham, J. V.

10.1101/535252 — epidemiology — Posted on 2019-02-08

2078 Amyloid conformers of the FXR1 protein prevent mRNA degradation in cortical neurons

Sopova, J.; Koshel, E.; Belashova, T.; Zadorsky, S.; Sergeeva, A.; Siniukova, V.; Shenfeld, A.; Velizhanina, M.; Volkov, K.; Nizhnikov, A.; Gaginskaya, E.; Galkin, A.

10.1101/544650 — neuroscience — Posted on 2019-02-08

2079 Touch DNA on objects can be analysed at low cost using simplified direct amplification methods

Gammon, K.; Murray-Jones, K.; Shenton, D.; Wood, Z.; Mayers, C.

10.1101/540823 — molecular biology — Posted on 2019-02-08

2080 Segment 2 from influenza A(H1N1)pdm09 viruses confers temperature sensitive HA yield on candidate vaccine virus growth in eggs that is complemented by PB2 701D

Hussain, S.; Turnbull, M. L.; Pinto, R. M.; McCauley, J. W.; Engelhardt, O. G.; Digard, P.

10.1101/541235 — microbiology — Posted on 2019-02-08

2081 Contrasting patterns of ERK activation in the tail of the striatum in response to aversive and rewarding signals

Gangarossa, G.; Castell, L.; Castro, L.; Tarot, P.; Veyrunes, F.; Vincent, P.; Bertaso, F.; Valjent, E.

10.1101/533299 — neuroscience — Posted on 2019-02-08

2082 Deficit in motor skill learning-dependent synaptic plasticity at motor cortex to Dorso Lateral Striatum synapses in a mouse model of Huntington's disease

Glangetas, C.; Espinosa, P.; Bellone, C.

10.1101/544718 — neuroscience — Posted on 2019-02-08

2083 A simplified spiking model of grid-cell scale and intrinsic frequencies

Santos-Pata, D.; Zucca, R.; Lopez Carral, H.; Verschure, P. F.

10.1101/544882 — neuroscience — Posted on 2019-02-08

2084 Molecular Mechanisms Driving Bistable Switch Behavior in Xylem Cell Differentiation

Turco, G. M.; Rodriguez-Medina, J.; Siebert, S.; Han, D.; Vahldick, H.; Shulse, C. N.; Cole, B. J.; Juliano, C.; Dickel, D. E.; Savageau, M. A.; Brady, S. M.

10.1101/543983 — plant biology — Posted on 2019-02-08

2085 Non-canonical Features of Pentatricopeptide Repeat Protein-Facilitated RNA Editing in Arabidopsis Chloroplasts

Sun, Y. K.; Gutmann, B.; Small, I.

10.1101/544486 — plant biology — Posted on 2019-02-08

2086 Horizontal transfer of prokaryotic cytolethal distending toxin B genes to eukaryotes

Verster, K. I.; Wisecaver, J. H.; Duncan, R. P.; Karageorgi, M.; Gloss, A. D.; Armstrong, E.; Price, D. K.; Menon, A. R.; Ali, Z. M.; Whiteman, N. K.

10.1101/544197 — evolutionary biology — Posted on 2019-02-08

2087 Arenaviridae exoribonuclease presents genomic RNA edition capacity.

Yekwa, E.; Aphibanthammakit, C.; Carnec, X.; Coutard, B.; Picard, C.; Canard, B.; Baize, S.; Ferron, F.

10.1101/541698 — biochemistry — Posted on 2019-02-08

2088 Optimal iron concentrations for growth-associated polyhydroxyalkanoate biosynthesis in the marine photosynthetic purple bacterium Rhodovulum sulfidophilum

Foong, C. P.; Higuchi-Takeuchi, M.; Numata, K.

10.1101/545053 — microbiology — Posted on 2019-02-08

2089 Photorhabdus Dam methyltransferase overexpression impairs virulence of the nemato-bacterial complex in insects

Payelleville, A.; Blackburn, D.; Lanois, A.; Pages, S.; Cambon, M.; Ginibre, N.; Clarke, D. J.; Givaudan, A.; Brillard, J.

10.1101/545061 — microbiology — Posted on 2019-02-08

2090 Genetic dissection of Rift Valley fever pathogenesis: Rfvs2 on mouse chromosome 11 enables survival to acute-onset hepatitis

Batista, L.; Jouvion, G.; Simon-Chazottes, D.; Houzelstein, D.; Burlen-Defranoux, O.; Boissiere, M.; Tokuda, S.; Zaverucha do Valle, T.; Cumano, A.; Flamand, M.; Montagutelli, X.; Panthier, J.-J.

10.1101/545129 — genetics — Posted on 2019-02-08

2091 Recombinant vector vaccines and within-host evolution

Bull, J. J.; Nuismer, S.; Antia, R.

10.1101/545087 — evolutionary biology — Posted on 2019-02-08

2092 A quantitative model of human neurodegenerative diseases involving protein aggregation

Kepp, K. P.

10.1101/541243 — neuroscience — Posted on 2019-02-08

2093 Pathogenic potential of Hic1 expressing cardiac stromal progenitors

Soliman, H.; Paylor, B.; Scott, W.; Lemos, D.; Chang, C.; Arostegui, M.; Low, M.; Lee, C.; Fiore, D.; Braghetta, P.; Pospichalova, V.; Barkauskas, C.; Korinek, V.; Rampazzo, A.; MacLeod, K.; Underhill, T. M.; Rossi, F.

10.1101/544403 — cell biology — Posted on 2019-02-08

2094 Oxygen restriction generates difficult-to-culture pathogens

Kvich, L. A.; Fritz, B. G.; Crone, S. G.; Kragh, K. N.; Kolpen, M.; Sonderholm, M.; Andersson, M.; Koch, A.; Jensen, P. O.; Bjarnsholt, T.

10.1101/339747 — microbiology — Posted on 2019-02-07

2095 Remodeling gut microbiota by Streptococcus thermophilus 19 attenuates inflammation in septic mice

Hu, D.; Wu, G.; Zhang, Y.; Yang, X.; Fang, Z.; Han, S.; Li, X.; Cai, W.; Xiao, D.; Liu, J.; Zhang, W.; Li, N.; Ji, P.; Hou, H.; Han, J.

10.1101/543967 — microbiology — Posted on 2019-02-08

2096 Deciphering the interstrand crosslink DNA repair network expressed by Trypanosoma brucei

Dattani, A.; Wilkinson, S. R.

10.1101/543975 — microbiology — Posted on 2019-02-08

2097 Who Are The Traditional Healers Treating Mental Illnesses In Rural Ethiopia? A population-Based Descriptive Study

Aschalew, A. B.; Sisay, M. M.; Wassie, A. F.

10.1101/543850 — epidemiology — Posted on 2019-02-08

2098 Altered cortical development and psychiatric symptom risk in adolescents exposed to maternal stress in utero

McQuaid, G. A.; Darcey, V. L.; Avalos, M. F.; Fishbein, D. H.; VanMeter, J. W.

10.1101/540930 — neuroscience — Posted on 2019-02-07

2099 Length of uninterrupted CAG repeats, independent of polyglutamine size, results in increased somatic instability and hastened age of onset in Huntington disease

Wright, G. E. B.; Collins, J. A.; Kay, C.; McDonald, C.; Dolzhenko, E.; Xia, Q.; Becanovic, K.; Semaka, A.; Nguyen, C. M.; Trost, B.; Richards, F.; Bijlsma, E. K.; Squitieri, F.; Scherer, S. W.; Eberle, M. A.; Yuen, R. K. C.; Hayden, M. R.

10.1101/533414 — genetics — Posted on 2019-02-07

2100 Natural variation in arsenic toxicity is explained by differences in branched chain amino acid catabolism

Zdraljevic, S.; Fox, B. W.; Strand, C.; Panda, O.; Tenjo-Castano, F. J.; Brady, S. C.; Crombie, T. A.; Doench, J. G.; Schroeder, F. C.; Andersen, E. C.

10.1101/373787 — genetics — Posted on 2019-02-07

2101 Estimating prevalence for limb-girdle muscular dystrophy based on public sequencing databases

Liu, W.; Pajusalu, S.; Lake, N. J.; Zhou, G.; Ioannidis, N.; Mittal, P.; Johnson, N. E.; Weihl, C. C.; Williams, B. A.; Albrecht, D. E.; Rufibach, L. E.; Lek, M.

10.1101/502708 — epidemiology — Posted on 2019-02-07

2102 Salicylic acid-driven association of LENRV and NIMIN1/NIMIN2 binding domain regions in the C-terminus of tobacco NPR1 transduces SAR signal

Neeley, D.; Konopka, E.; Straub, A.; Maier, F.; Pfitzner, A. J. P.; Pfitzner, U.

10.1101/543645 — plant biology — Posted on 2019-02-07

2103 Recent adverse mortality trends in Scotland: comparison with other high-income countries.

Fenton, L.; Minton, J.; Ramsay, J.; Kaye-Bardgett, M.; Fischbacher, C.; Wyper, G. M.; McCartney, G.

10.1101/542449 — epidemiology — Posted on 2019-02-07

2104 Cell wall integrity signaling regulates cell wall regeneration via transcriptional activation in Chlamydomonas reinhardtii

Cronmiller, E.; Toor, D.; Shao, N. C.; Kariyawasam, T.; Wang, M. H.; Lee, J.-H.

10.1101/543280 — plant biology — Posted on 2019-02-07

2105 Genome wide analysis of Ga1-s modifiers in maize

Hurst, P.; Liang, Z.; Smith, C.; Yerka, M.; Sigmon, B.; Rodriguez, O.; Schnable, J. C.

10.1101/543264 — plant biology — Posted on 2019-02-07

2106 Prediction of prospective leaf morphology in lettuce based on intracellular chloroplast position

Hikawa, M.; Nishizawa, K.; Kodama, Y.

10.1101/543538 — plant biology — Posted on 2019-02-07

2107 Altered cortical development and psychiatric symptom risk in adolescents exposed to maternal stress in utero

McQuaid, G. A.; Darcey, V. L.; Avalos, M. F.; VanMeter, J. W.; Fishbein, D. H.

10.1101/540930 — neuroscience — Posted on 2019-02-07

2108 Conformational switching of CD81 controls its function as a receptor for hepatitis C virus

Palor, M.; Stejskal, L.; Mandal, P.; Shepherd, A. J.; Grove, J.

10.1101/542837 — molecular biology — Posted on 2019-02-07

2109 Evolution and rapid spread of a reassortant A(H3N2) virus that predominated the 2017-2018 influenza season

Potter, B. I.; Garten, R.; Hadfield, J.; Huddleston, J.; Barnes, J.; Rowe, T.; Guo, L.; Xu, X.; Neher, R. A.; Bedford, T.; Wentworth, D.

10.1101/543322 — genomics — Posted on 2019-02-07

2110 Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests

Meccariello, A.; Salvemini, M.; Primo, P.; Hall, B.; Koskinioti, P.; Dalikova, M.; Gravina, A.; Gucciardino, M. A.; Forlenza, F.; Gregoriou, M. E.; Ippolito, D.; Monti, S. M.; Petrella, V.; Perrotta, M. M.; Schmeing, S.; Ruggiero, A.; Scolari, F.; Giordano, E.; Tsoumani, K. T.; Marec, F.; Windbichler, N.; Nagaraju, J.; Arunkumar, K. P.; Bourtzis, K.; Mathiopoulos, K. D.; Ragoussis, J.; Vitagliano, L.; Tu, Z.; Papathanos, P. A.; Robinson, M. D.; Saccone, G.

10.1101/533646 — genetics — Posted on 2019-02-07

2111 Evolutionary dynamics of de novo mutations and mutant lineages arising in a simple, constant environment

Kinnersley, M.; Schwartz, K.; Boswell, J.; Yang, D.-D.; Sherlock, G.; Rosenzweig, F.

10.1101/540625 — evolutionary biology — Posted on 2019-02-07

2112 Socioeconomic inequality in recent adverse mortality trends in Scotland.

Fenton, L.; Wyper, G. M.; McCartney, G.; Minton, J.

10.1101/542472 — epidemiology — Posted on 2019-02-07

2113 The role of p-21 activated kinases (PAKs) in glucose homeostasis and skeletal muscle glucose uptake

Moller, L. L. V.; Jaurji, M.; Nielsen, I. L.; Joseph, G. A.; Kjobsted, R.; Knudsen, J. R.; Madsen, A. B.; Schjerling, P.; Jensen, T. E.; Krauss, R. S.; Richter, E. A.; Sylow, L.

10.1101/543736 — cell biology — Posted on 2019-02-07

2114 Proteomic and Transcriptomic Profiling Identifies Mediators of Anchorage-Independent Growth and Roles of Inhibitor of Differentiation Proteins in Invasive Lobular Breast Cancer

Tasdemir, N.; Ding, K.; Levine, K. M.; Du, T.; Bossart, E. A.; Lee, A. V.; Davidson, N. E.; Oesterreich, S.

10.1101/543132 — cancer biology — Posted on 2019-02-07

2115 The IDH-Tau-EGFR triad defines diffuse glioma pathology by controlling mesenchymal differentiation and neo-vascular fitness.

Gargini, R.; Segura-Collar, B.; Hernandez-SanMiguel, E.; Garcia-Escudero, V.; Romero-Bravo, A.; Herranz, B.; Nunez, F. J.; Garcia-Perez, D.; Ayuso-Sacido, A.; Seoane, J.; Sepulveda-Sanchez, J. M.; Hernandez-Lain, A.; Castro, M. G.; Garcia-Escudero, R.; Avila, J.; Sanchez-Gomez, P.

10.1101/541326 — cancer biology — Posted on 2019-02-07

2116 Quantification of multicellular colonization in tumor metastasis using exome sequencing data

Nishino, J.; Watanabe, S.; Miya, F.; Kamatani, T.; Boroevich, K.; Tsunoda, T.

10.1101/542324 — cancer biology — Posted on 2019-02-07

2117 Molecular and functional heterogeneity of cancer associated fibroblasts in high-grade serous ovarian cancer

Hussain, A.; Voisin, V.; Poon, S.; Dmytryshyn, J.; Richman, C.; Meens, J.; Ho, V. W.; Tang, K. H.; Paterson, J.; Clarke, B.; Bernardini, M.; Bader, G.; Neel, B.; Ailles, L.

10.1101/519728 — cancer biology — Posted on 2019-02-07

2118 More accurate transcript assembly via parameter advising

DeBlasio, D.; Kim, K.; Kingsford, C.

10.1101/342865 — bioinformatics — Posted on 2019-02-07

2119 The molecular basis of hypercontractility caused by the hypertrophic cardiomyopathy mutations R403Q and R663H

Sarkar, S. S.; Trivedi, D. V.; Morck, M. M.; Adhikari, A. S.; Pasha, S. N.; Ruppel, K. M.; Spudich, J. A.

10.1101/543413 — biochemistry — Posted on 2019-02-07

2120 Integrative analysis of Hydra head regeneration reveals activation of distal enhancer-like elements

Murad, R.; Macias-Munoz, A.; Wong, A.; Ma, X.; Mortazavi, A.

10.1101/544049 — genomics — Posted on 2019-02-07

2121 C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

Sowamber, R.; Chehade, R.; Bitar, M.; Dodds, L.; Milea, A.; Shaw, P.; George, S. H.

10.1101/528885 — cancer biology — Posted on 2019-02-07

2122 Multi-allelic APRR2 Gene is Associated with Fruit Pigment Accumulation in Melon and Watermelon

Oren, E.; Tzuri, G.; Vexler, L.; Dafna, A.; Meir, A.; Saar, U.; Faigenboim, A.; Kenigswald, M.; Portnoy, V.; Schaffer, A. A.; Levi, A.; Buckler, E. S.; Katzir, N.; Burger, J.; Tadmor, Y.; Gur, A.

10.1101/542282 — plant biology — Posted on 2019-02-07

2123 Endogenous oxytocin inhibits hypothalamic stress responsive neurons following acute hypernatremia

Pati, D.; Harden, S. W.; Kelly, K. B.; de Kloet, A. D.; Krause, E. G.; Frazier, C. J.

10.1101/543165 — neuroscience — Posted on 2019-02-07

2124 Extracellular mycobacterial DNA drives disease progression by triggering Caspase-11-dependent pyroptosis of infected macrophages

Varela, M.; van der Vaart, M.; Groenewoud, A.; Meijer, A. H.

10.1101/514125 — immunology — Posted on 2019-02-07

2125 Theoretical modeling on CRISPR-coded cell lineages: efficient encoding and optimal reconstruction

Sugino, K.; Garcia Marques, J.; Espinosa Medina, I.; Lee, T.

10.1101/538488 — developmental biology — Posted on 2019-02-07

2126 HOPS: Automated detection and authentication of pathogen DNA in archaeological remains

Huebler, R.; Key, F. M.; Warinner, C.; Bos, K. I.; Krause, J.; Herbig, A.

10.1101/534198 — bioinformatics — Posted on 2019-02-07

2127 Inhibiting histone acetyltransferase activity rescues differentiation of emerin-null myogenic progenitors

Bossone, K. A.; Ellis, J. A.; Holaska, J. M.

10.1101/437343 — cell biology — Posted on 2019-02-07

2128 Bayesian estimation for stochastic gene expression using multifidelity models

Vo, H. D.; Fox, Z. R.; Baetica, A.; Munsky, B.

10.1101/468090 — systems biology — Posted on 2019-02-07

2129 Limited One-time Sampling Irregularity Map (LOTS-IM): Automatic Unsupervised Quantitative Assessment of White Matter Hyperintensities in Structural Brain Magnetic Resonance Images

Rachmadi, M. F.; Valdes Hernandez, M.; Li, H.; Guerrero, R.; Meijboom, R.; Wiseman, S.; Waldman, A.; Zhang, J.; Rueckert, D.; Komura, T.

10.1101/334292 — neuroscience — Posted on 2019-02-07

2130 Studying Human Behaviour with Virtual Reality: The Unity Experiment Framework

Brookes, J.; Warburton, M.; Alghadier, M.; Mushtaq, F.; Mon-Williams, M.

10.1101/459339 — neuroscience — Posted on 2019-02-07

2131 Assessment of bilateral knee pain from MR imaging using deep neural networks

Chang, G. H.; Felson, D. T.; Qiu, S.; Capellini, T. D.; Kolachalama, V. B.

10.1101/463497 — bioengineering — Posted on 2019-02-07

2132 The unique coding sequence of pmoCAB operon from type Ia methanotrophs simultaneously optimizes transcription and translation

Villada, J. C.; Duran, M. F.; Lee, P. K. H.

10.1101/543546 — microbiology — Posted on 2019-02-07

2133 Cohort Profile: East London Genes & Health (ELGH), a community based population genomics and health study of British-Bangladeshi and British-Pakistani people.

Finer, S.; Martin, H.; Hunt, K. A.; MacLaughlin, B.; Ashcroft, R.; Khan, A.; McCarthy, M. I.; Robson, J.; MacArthur, D.; Griffiths, C.; Wright, J.; Trembath, R. C.; van Heel, D.

10.1101/426163 — genomics — Posted on 2019-02-07

2134 Multi-model inference of non-random mating from an information theoretic approach

Carvajal-Rodriguez, A.

10.1101/305730 — evolutionary biology — Posted on 2019-02-07

2135 Intrinsic temporal tuning of neurons in the optic tectum is shaped by multisensory experience

Busch, S. E.; Khakhalin, A. S.

10.1101/540898 — neuroscience — Posted on 2019-02-07

2136 Local Targeted Memory Reactivation in Human Sleep

Bar, E.; Arzi, A.; Perl, O.; Livne, E.; Sobel, N.; Dudai, Y.; Nir, Y.

10.1101/539114 — neuroscience — Posted on 2019-02-07

2137 Patterns of African and Asian admixture in the Afrikaner population of South Africa

Hollfelder, N.; Erasmus, J. C.; Hammaren, R.; Vicente, M.; Jakobsson, M.; Greeff, J. M.; Schlebusch, C. M.

10.1101/542761 — evolutionary biology — Posted on 2019-02-07

2138 Performance of neural network basecalling tools for Oxford Nanopore sequencing

Wick, R. R.; Judd, L. M.; Holt, K. E.

10.1101/543439 — bioinformatics — Posted on 2019-02-07

2139 The isotopic N turnover rate as a proxy to evaluate in the long-term the protein turnover in growing ruminants

Cantalapiedra-Hijar, G.; Fouillet, H.; Chantelauze, C.; Khodorova, N.; Bahloul, L.; Ortigues-Marty, I.

10.1101/543116 — physiology — Posted on 2019-02-07

2140 A physiological approach to the ecology and evolution of flowers

Roddy, A.

10.1101/539668 — ecology — Posted on 2019-02-07

2141 Structural redundancy in supracellular actomyosin networks enables robust tissue folding

Yevick, H. G.; Miller, P. W.; Dunkel, J.; Martin, A. C.

10.1101/530816 — developmental biology — Posted on 2019-02-07

2142 Networked information interactions of epileptic EEG based on symbolic transfer entropy

Wenpo, Y.; Jun, W.

10.1101/543496 — biophysics — Posted on 2019-02-07

2143 A novel algorithm for the collective integration of single cell RNA-seq during embryogenesis

Gong, W.; Singh, B. N.; Shah, P.; Das, S.; Theisen, J.; Chan, S.; Kyba, M.; Garry, M. G.; Yannopoulos, D.; Pan, W.; Garry, D. J.

10.1101/543314 — bioinformatics — Posted on 2019-02-07

2144 Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development

Caldelari, R.; Dogga, S.; Schmid, M. W.; Franke-Fayard, B.; Janse, C. J.; Soldati-Favre, D.; Heussler, V.

10.1101/543207 — microbiology — Posted on 2019-02-07

2145 Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models

Cladel, N.; Jiang, P.; Li, J.; Peng, X.; Cooper, T.; Majerciak, V.; Balogh, K.; Meyer, T.; Brendle, S.; Budgeon, L.; Shearer, D.; Munden, R.; Cam, M.; Vallur, R.; Christensen, N.; Zheng, Z.-M.; Hu, J.

10.1101/541474 — microbiology — Posted on 2019-02-07

2146 Characterising the loss-of-function impact of 5' untranslated region variants in whole genome sequence data from 15,708 individuals

Whiffin, N.; Karczewski, K. J.; Zhang, X.; Chothani, S.; Smith, M. J.; Evans, D. G.; Roberts, A. M.; Quaife, N. M.; Schafer, S.; Rackham, O.; Alfoldi, J.; O'Donnell-Luria, A. H.; Francioli, L. C.; Genome Aggregation Database (gnomAD) Production Team, ; Genome Aggregation Database (gnomAD) Consortium, ; Cook, S. A.; Barton, P. J. R.; MacArthur, D. G.; Ware, J. S.

10.1101/543504 — genomics — Posted on 2019-02-07

2147 Marked compositional changes in harvestmen assemblages in Amazonian forest islands induced by a mega dam

Tourinho, A. L.; Benchimol, M.; Porto, W.; Peres, C.; Storck Tonon, D.

10.1101/542969 — ecology — Posted on 2019-02-07

2148 Duo-activation of PKA and PKG by PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against proteinopathy

Zhang, H.; Pan, B.; Rekhter, M. D.; Goldberg, A. L.; Wang, X.

10.1101/543785 — cell biology — Posted on 2019-02-07

2149 A semi-automatic dispenser for solid and liquid food in aquatic facilities

Candelier, R.; Bois, A.; Tronche, S.; Mahieu, J.; Mannioui, A.

10.1101/535062 — biophysics — Posted on 2019-02-07

2150 Possible Magneto-Mechanical and Magneto-Thermal Mechanisms of Ion Channel Activation by Iron-Loaded Ferritin in Magnetogenetics

Barbic, M.

10.1101/540351 — bioengineering — Posted on 2019-02-07

2151 Greater BOLD signal during successful emotional stimulus reappraisal is associated with better dietary self-control

Maier, S. U.; Hare, T. A.

10.1101/542712 — neuroscience — Posted on 2019-02-07

2152 Dynamics of cortical degeneration over a decade in Huntington's Disease

Johnson, E. B.; Ziegler, G.; Penny, W.; Rees, G.; Tabrizi, S. J.; Scahill, R. I.; Gregory, S.

10.1101/537977 — neuroscience — Posted on 2019-02-07

2153 Information and genetic counselling for psychiatric risks in children with rare disorders

Cuthbert, A.; Challenger, A.; Hall, J.; van den Bree, M.

10.1101/542423 — genetics — Posted on 2019-02-07

2154 MOCHI enables discovery of heterogeneous interactome modules in 3D nucleome

Tian, D.; Zhang, R.; Zhang, Y.; Zhu, X.; Ma, J.

10.1101/542092 — bioinformatics — Posted on 2019-02-07

2155 Moisture-dependent morphing tunes the dispersal of dandelion diaspores

Seale, M.; Zhdanov, O.; Cummins, C.; Kroll, E.; Blatt, M. R.; Zare-Behtash, H.; Busse, A.; Mastropaolo, E.; Viola, I. M.; Nakayama, N.

10.1101/542696 — plant biology — Posted on 2019-02-07

2156 A fronto-temporo-parietal network disambiguates potential objects of joint attention

Kraemer, P. M.; Görner, M.; Ramezanpour, H.; Dicke, P. W.; Thier, P.

10.1101/542555 — neuroscience — Posted on 2019-02-07

2157 Predictability in the evolution of Orthopteran cardenolide insensitivity

Yang, L.; Ravikanthachari, N.; Marino-Perez, R.; Deshmukh, R.; Wu, M.; Rosenstein, A.; Kunte, K.; Song, H.; Andolfatto, P.

10.1101/542811 — evolutionary biology — Posted on 2019-02-07

2158 The cloud forest in the Dominican Republic: diversity and conservation status

Cano Ortiz, A.; Musarella, C. M.; Quinto Canas, R.; Pinar Fuentes, J. C.; Pinto Gomes, C. J.; Cano, E.

10.1101/543892 — plant biology — Posted on 2019-02-07

2159 In-vitro pathogen inhibition: Comparing the inhibitory effects of a complex multistrain synbiotic with simple probiotics containing the yeast Saccharomyces boulardii or Lactobacillus rhamnosus bacteria

Piatek, J.; Sommermeyer, H.; Ciechelska-Rybarczyk, A.; Bernatek, M.

10.1101/543819 — microbiology — Posted on 2019-02-07

2160 Threonine synthase CoTHR4 is involved in infection-related morphogenesis during the pre-penetration stage in Colletotrichum orbiculare

Harata, K.; Okuno, T.

10.1101/543827 — microbiology — Posted on 2019-02-07

2161 Evolution of leaf-cutter behavior in bees (Hymenoptera: Megachilidae) as inferred from total-evidence tip-dating analyses

Gonzalez Betancourt, V. H.; Gustafson, G. T.; Engel, M. S.

10.1101/543082 — evolutionary biology — Posted on 2019-02-07

2162 Investigating the effectiveness of school health services delivered by a health provider: a systematic review of systematic reviews

Levinson, J.; Kohl, K.; Baltag, V.; Ross, D. A.

10.1101/543868 — epidemiology — Posted on 2019-02-07

2163 Tobacco use and associated factors among Rwandan youth aged 15-34 years: Findings from a nationwide survey, 2013

HABIYAREMYE, F.; Rwunganira, S.; Musanabaganwa, C.; Muhimpundu, M. A.

10.1101/543843 — epidemiology — Posted on 2019-02-07

2164 Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance

Lo, E.; Hostetler, J. B.; Yewhalaw, D.; Pearson, R. D.; Hamid, M. M. A.; Gunalan, K.; Kepple, D.; Ford, A.; Janies, D. A.; Rayner, J. C.; Miller, L. H.; Yan, G.

10.1101/543959 — epidemiology — Posted on 2019-02-07

2165 Estimating the rate and determinants of exclusive breastfeeding practices among rural mothers in Southern Ghana.

Manyeh, A. K.; Amu, A.; Ekey, R. A.; Akpakli, D. E.; Williams, J. E.; Gyapong, M.

10.1101/543884 — epidemiology — Posted on 2019-02-07

2166 Spatial eco-evolutionary feedbacks mediate coexistence inprey-predator systems

Colombo, E. H.; Martinez-Garcia, R.; Lopez, C.; Hernandez-Garcia, E.

10.1101/543934 — ecology — Posted on 2019-02-07

2167 Loss of function of the RNA export factor, Nxt1, in Drosophila causes muscle degeneration and reduced expression of genes with long introns.

van der Graaf, K.; White-Cooper, H.

10.1101/543942 — developmental biology — Posted on 2019-02-07

2168 Identification of key genes and pathways associated with Crohn's disease by bioinformatics analysis

Wang, Z.; Zhu, J.; Ma, L.

10.1101/543835 — bioinformatics — Posted on 2019-02-07

2169 Assessment of the cardiovascular adverse effects of drug-drug interactions through a combined analysis of spontaneous reports and predicted drug-target interactions

Ivanov, S.; Lagunin, A.; Filimonov, D.; Poroikov, V.

10.1101/543918 — bioinformatics — Posted on 2019-02-07

2170 Updating the in silico human surfaceome with meta-ensemble learning and feature engineering

Bojar, D.

10.1101/499780 — bioinformatics — Posted on 2019-02-07

2171 MS.liverK: an R package for transcriptome-based computation of molecular subtypes and functional signatures in liver cancer

Petitprez, F.; Meunier, L.; Letouze, E.; Hoshida, Y.; Villanueva, A.; Llovet, J.; Thorgeirsson, S.; Wang, X. W.; Fridman, W. H.; Zucman-Rossi, J.; de Reynies, A.

10.1101/540005 — bioinformatics — Posted on 2019-02-07

2172 Intrinsic structure of model-derived metrics for in silico proarrhytmic riskassessment identified by global sensitivity analysis

Parikh, J.; Di Achille, P.; Kozloski, J.; Gurev, V.

10.1101/543926 — pharmacology and toxicology — Posted on 2019-02-07

2173 The development of spatiotemporal organization of episodic memory in children and its disruption in Williams Syndrome

Mastrogiuseppe, M.; Bertelsen, N.; Bedeschi, M. F.; Lee, S. A.

10.1101/534743 — neuroscience — Posted on 2019-02-07

2174 Prosody perception in children: studying individual differences with novel brain and behavioral approaches

Myers, B.; Vaughan, C.; Soman, U.; Blain, S.; Korsnack, K.; Camarata, S.; Gordon, R.

10.1101/281998 — neuroscience — Posted on 2019-02-07

2175 A primer genetic toolkit for exploring mitochondrial biology and disease using zebrafish

Sabharwal, A.; Campbell, J. M.; WareJoncas, Z.; Wishman, M.; Ata, H.; Liu, W.; Ichino, N.; Bergren, J. D.; Urban, M. D.; Urban, R.; Poshusta, T. L.; Ding, Y.; Xu, X.; Clark, K. J.; Ekker, S. C.

10.1101/542084 — molecular biology — Posted on 2019-02-07

2176 Progranulin deficiency leads to reduced glucocerebrosidase activity

Zhou, X.; Paushter, D. H.; Pagan, M. D.; Kim, D.; Lieberman, R. L.; Overkleeft, H. S.; Sun, Y.; Smolka, M. B.; Hu, F.

10.1101/540450 — neuroscience — Posted on 2019-02-07

2177 Oxygen restriction generates difficult-to-culture pathogens

Kvich, L. A.; Fritz, B. G.; Crone, S. G.; Kragh, K. N.; Kolpen, M.; Sonderholm, M.; Andersson, M.; Koch, A.; Jensen, P. O.; Bjarnsholt, T.

10.1101/339747 — microbiology — Posted on 2019-02-07

2178 Extracellular mycobacterial DNA triggers drives disease progression by triggering Caspase-11-dependent pyroptosis of infected macrophages

Varela, M.; van der Vaart, M.; Groenewoud, A.; Meijer, A. H.

10.1101/514125 — immunology — Posted on 2019-02-07

2179 Bayesian Estimation of Species Divergence Times Using Correlated Quantitative Characters

Alvarez-Carretero, S.; Goswami, A.; Yang, Z.; dos Reis, M.

10.1101/441105 — evolutionary biology — Posted on 2019-02-07

2180 Combinations of low-level and high-level neural processes can account for distinct patterns of context-dependent choice

Spitmaan, M.; Horno, O.; Chu, E.; Soltani, A.

10.1101/508655 — neuroscience — Posted on 2019-02-07

2181 Attention Promotes the Neural Encoding of Prediction Errors

Smout, C. A.; Tang, M. F.; Garrido, M. I.; Mattingley, J. B.

10.1101/522185 — neuroscience — Posted on 2019-02-07

2182 Is understanding the structure-function of microbial community of sludge suitable using DNA-based molecular methods?

Wang, P.; Wang, Z.; Ma, J.

10.1101/536508 — ecology — Posted on 2019-02-07

2183 Chicory demonstrates substantial water uptake from below 2 m, but still did not escape topsoil drought

Rasmussen, C. R.; Thorup-Kristensen, K.; Dresboll, D. B.

10.1101/494906 — plant biology — Posted on 2019-02-07

2184 Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

John, C.; Reeve, N. F.; Free, R. C.; Williams, A. T.; Farmaki, A.-E.; Bethea, J.; Barton, L. M.; Shrine, N.; Batini, C.; Packer, R.; Terry, S.; Hargadon, B.; Wang, Q.; Melbourne, C.; Adams, E. L.; Bee, C. E.; Harrington, K.; Miola, J.; Brunskill, N. J.; Brightling, C. E.; Barwell, J.; Wallace, S. E.; Hsu, R.; Shepherd, D. J.; Hollox, E. J.; Wain, L. V.; Tobin, M. D.

10.1101/422782 — epidemiology — Posted on 2019-02-07

2185 A stochastic model for error correction of kinetochore-microtubule attachments and its coupling to the spindle assembly checkpoint

Banerjee, A.; Adames, N.; Peccoud, J.; Tyson, J. J.

10.1101/541573 — systems biology — Posted on 2019-02-07

2186 The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain

Karolis, V.; Corbetta, M.; Thiebaut de Schotten, M.

10.1101/372300 — neuroscience — Posted on 2019-02-07

2187 Integrating transcriptomic network reconstruction and QTL analyses reveals mechanistic connections between genomic architecture and Brassica rapa development

Baker, R. L.; Leong, W.; Brock, M. T.; Rubin, M. J.; Markelz, R. J. C.; Welch, S.; Maloof, J. N.; Weinig, C.

10.1101/540740 — genomics — Posted on 2019-02-07

2188 Inter- and Intra-Generation Genomic Predictions for Douglas-fir Growth in Unobserved Environments

Ratcliffe, B.; Thistlethwaite, F. R.; Gamal El-Dien, O.; Cappa, E.; Porth, I.; Klapste, J.; Chen, C.; Wang, T.; Stoehr, M. U.; El-Kassaby, Y. A.

10.1101/540765 — genetics — Posted on 2019-02-07

2189 Epidemiological Analysis of Ear Diseases in 221 Dogs in Northwest of China

Lu, D.; Tang, F.-L.; Yang, H.-Q.; Ma, X.-W.

10.1101/541516 — epidemiology — Posted on 2019-02-07

2190 Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis

Campsie, P.; Childs, P. G.; Robertson, S. N.; Cameron, K.; Hough, J.; Salmeran-Sanchez, M.; Tsimbouri, M. P.; Vichare, P.; Dalby, M. J.; Reid, S.

10.1101/543660 — cell biology — Posted on 2019-02-07

2191 Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

Fekri, F.; Abousawan, J.; Bautista, S. J.; Dayam, R. M.; Antonescu, C.; Karshafian, R.

10.1101/543355 — cell biology — Posted on 2019-02-07

2192 Ramping and phasic dopamine activity accounts for efficient cognitive resource allocation during reinforcement learning.

Song, M. R.; Lee, S. W.

10.1101/381103 — neuroscience — Posted on 2019-02-07

2193 Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages

Beale, M. A.; Marks, M.; Sahi, S. K.; Tantalo, L. C.; Nori, A. V.; French, P.; Lukehart, S. A.; Marra, C. M.; Thomson, N. R.

10.1101/413161 — genomics — Posted on 2019-02-07

2194 Lactate and pyruvate promote cellular stress resistance and longevity through ROS signaling.

Tauffenberger, A.; Fiumelli, H.; Almustafa, S.; Magistretti, P. J.

10.1101/542316 — cell biology — Posted on 2019-02-07

2195 An RNA-binding protein secreted by Listeria monocytogenes activates RIG-I signaling

Pagliuso, A.; Tham, T. N.; Allemand, E.; Robertin, S.; Dupuy, B.; Bertrand, Q.; Becavin, C.; Koutero, M.; Najburg, V.; Nahori, M.-A.; Stavru, F.; Dessen, A.; Muchard, C.; Lebreton, A.; Komarova, A. V.; Cossart, P.

10.1101/543652 — cell biology — Posted on 2019-02-07

2196 Murine Surf4 is essential for early embryonic development

Emmer, B. T.; Lascuna, P. J.; Kotnik, E.; Saunders, T.; Khoriaty, R.; Ginsburg, D.

10.1101/541995 — cell biology — Posted on 2019-02-07

2197 Spatiotemporal dissection of the cell cycle regulated human proteome

Mahdessian, D.; Sullivan, D.; Danielsson, F.; Arif, M.; Zhang, C.; Akesson, L.; Gnann, C.; Schutten, R.; Thul, P.; Carja, O.; Ayoglu, B.; Mardinoglu, A.; Ponten, F.; Uhen, M.; Lindskog, C.; Lundberg, E.

10.1101/543231 — cell biology — Posted on 2019-02-07

2198 Customizing material into embodied cap by sponge crab

Harada, K.; Kagaya, K.

10.1101/330787 — animal behavior and cognition — Posted on 2019-02-07

2199 Evosep One Enables Robust Quantitative Deep Proteome Coverage using Tandem Mass Tags while Significantly Reducing Instrument Time

Krieger, J. R.; Wybenga-Groot, L. E.; Tong, J.; Bache, N.; Tsao, M. S.; Moran, M. F.

10.1101/543371 — systems biology — Posted on 2019-02-07

2200 Evidence for rapid evolution in a grassland biodiversity experiment

van Moorsel, S. J.; Schmid, M. W.; Wagemaker, C. A. M.; van Gurp, T.; Schmid, B.; Vergeer, P.

10.1101/262303 — ecology — Posted on 2019-02-07

2201 Gut microbiota influence B cell function in a TLR5-dependent manner

Li, S.; Walters, W.; Chassaing, B.; Zhang, B.; Shi, Q.; Waters, J.; Gewirtz, A. T.; Leifer, C. A.; Ley, R.

10.1101/537894 — immunology — Posted on 2019-02-07

2202 Hallucinations both in and out of context: An Active Inference Account

Benrimoh, D.; Parr, T.; Adams, R. A.; Friston, K.

10.1101/540419 — neuroscience — Posted on 2019-02-07

2203 Androgens enhance adult hippocampal neurogenesis in males but not females in an age-dependent manner

Duarte-Guterman, P.; Hamson, D.; Wainwright, S.; Chow, C.; Chaiton, J.; Lieblich, S. E.; Watson, N. V.; Galea, L. A.

10.1101/539296 — neuroscience — Posted on 2019-02-07

2204 Accurate sequence variant genotyping in cattle using variation-aware genome graphs

Crysnanto, D.; Wurmser, C.; Pausch, H.

10.1101/460345 — genomics — Posted on 2019-02-07

2205 Evolutionary rates are correlated between cockroach symbiont and mitochondrial genomes

Arab, D. A.; Bourguignon, T.; Wang, Z.; Ho, S. Y. W.; Lo, N.

10.1101/542241 — evolutionary biology — Posted on 2019-02-07

2206 DisCVR: Rapid viral diagnosis from high-throughput sequencing data

Maabar, M.; Davison, A. J.; Thorburn, F.; Gunson, R.; Palmarini, M.; Hughes, J.

10.1101/527127 — bioinformatics — Posted on 2019-02-07

2207 SHORT COMMUNICATION: Validation of a novel milk progesterone based tool to monitor luteolysis in dairy cows. Performance on cost-effective, on-farm measured data

Adriaens, I.; Saeys, W.; Geerinckx, K.; De Ketelaere, B.; Aernouts, B.

10.1101/526061 — bioengineering — Posted on 2019-02-07

2208 Connecting genetic incompatibilities with natural selection on additive genetic variation during adaptive radiation

Walter, G. M.; Aguirre, J. D.; Wilkinson, M. J.; Richards, T. J.; Blows, M. W.; Ortiz-Barrientos, D.

10.1101/520809 — evolutionary biology — Posted on 2019-02-07

2209 Statistically consistent divide-and-conquer pipelines for phylogeny estimation using NJMerge

Molloy, E. K.; Warnow, T.

10.1101/469130 — evolutionary biology — Posted on 2019-02-07

2210 Poly-Enrich: Count-based Methods for Gene Set Enrichment Testing with Genomic Regions

Lee, C. T.; Cavalcante, R. G.; Lee, C.; Qin, T.; Patil, S.; Wang, S.; Tsai, Z. T.; Boyle, A. P.; Sartor, M. A.

10.1101/488734 — bioinformatics — Posted on 2019-02-07

2211 Root Anatomy based on Root Cross-Section Image Analysis with Deep Learning

Wang, C.; Li, X.; Caragea, D.; Bheemanahalli, R.; Jagadish, S. V. K.

10.1101/442244 — bioinformatics — Posted on 2019-02-06

2212 Evaluation of Deep Learning Strategies for Nucleus Segmentation in Fluorescence Images

Caicedo, J. C.; Roth, J.; Goodman, A.; Becker, T.; Karhohs, K. W.; Broisin, M.; Csaba, M.; McQuin, C.; Singh, S.; Theis, F.; Carpenter, A. E.

10.1101/335216 — bioinformatics — Posted on 2019-02-06

2213 Building Large Updatable Colored de Bruijn Graphs via Merging

Muggli, M. D.; Alipanahi, B.; Boucher, C.

10.1101/229641 — bioinformatics — Posted on 2019-02-06

2214 Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling

Murphy, B. J.; Klusch, N.; Langer, J. D.; Mills, D. J.; Yildiz, O.; Kühlbrandt, W.

10.1101/543108 — biochemistry — Posted on 2019-02-06

2215 Kilohertz in vivo imaging of neural activity

Wu, J.; liang, Y.; Hsu, C.-L.; Chavarha, M.; Evans, S.; Shi, D.; Lin, M.; Tsia, K.; Ji, N.

10.1101/543058 — neuroscience — Posted on 2019-02-06

2216 Soluble tubulin is locally enriched at mitotic centrosomes in C. elegans

Baumgart, J.; Kirchner, M.; Redemann, S.; Woodruff, J.; Verbavatz, J.-M.; Julicher, F.; Hyman, A.; Mueller-Reichert, T.; Brugues, J.

10.1101/543066 — cell biology — Posted on 2019-02-06

2217 Ligand dependent gene regulation by transient ERα clustered enhancers

Saravanan, B.; Soota, D.; Islam, Z.; Jayani, R. S.; Mann, R.; Farooq, U.; Meel, S.; Walavalkar, K.; Gayen, S.; Singh, A. K.; Hannenhalli, S.; Notani, D.

10.1101/541540 — molecular biology — Posted on 2019-02-06

2218 Integrative Functional Network Interactions Underlie the Association between Physical Activity and Cognition in Neurodegenerative Diseases

Shih, C.-H.; Sklerov, M.; Browner, N.; Dayan, E.

10.1101/542936 — neuroscience — Posted on 2019-02-06

2219 Intracranial EEG reveals bihemispheric parietal and extra parietal brain networks supporting mental arithmetic

Umbach, G.; Rugg, M.; Worrell, G.; Sperling, M.; Gross, R.; Jobst, B.; Jacobs, J.; Zaghloul, K.; Stein, J.; Davis, K.; Lega, B.

10.1101/542142 — neuroscience — Posted on 2019-02-06

2220 Using a large-scale biodiversity monitoring dataset to test the effectiveness of protected areas at conserving North-American breeding birds

Cazalis, V.; Belghali, S.; Rodrigues, A. S. L.

10.1101/433037 — ecology — Posted on 2019-02-06

2221 Spiking allows neurons to estimate their causal effect

Lansdell, B. J.; Kording, K. P.

10.1101/253351 — neuroscience — Posted on 2019-02-06

2222 Epidemiology, ecology and human perceptions of snakebites in a savanna community of northern Ghana

Musah, Y.; Ameade, E. P. K.; Attuquayefio, D. K.; Holbech, L. H.

10.1101/543009 — ecology — Posted on 2019-02-06

2223 Long-Term historical and Projected Herbivore Population Dynamics in Ngorongoro Crater, Tanzania

Ogutu, J. O.; Moehlman, P. D.; Piepho, H.-P.; Runyoro, V. A.; Coughenour, M. B.; Boone, R.

10.1101/542910 — ecology — Posted on 2019-02-06

2224 Responses of soil physical, chemical and biochemical properties to short-term impact of tillage in an alfisol under maize (Zea mays L.) cultivation

Adegaye, A. C.; Adejoro, S.; Oladele, S.; Arotupin, D.; Ojeniyi, S.

10.1101/542944 — ecology — Posted on 2019-02-06

2225 Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases

Yambire, K. F.; Fernandez-Mosquera, L.; Steinfeld, R.; Muehle, C.; Ikonen, E.; Milosevic, I.; Raimundo, N.

10.1101/381376 — cell biology — Posted on 2019-02-06

2226 Aurora kinase Ipl1 facilitates bilobed distribution of clustered kinetochores to ensure error-free chromosome segregation in Candida albicans

Varshney, N.; Sanyal, K.

10.1101/542605 — cell biology — Posted on 2019-02-06

2227 Guiding dose selection of monoclonal antibodies using a new parameter (AFTIR) for characterizing ligand binding systems

Ahmed, S.; Ellis, M.; Li, H.; Pallucchini, L.; Stein, A. M.

10.1101/432500 — pharmacology and toxicology — Posted on 2019-02-06

2228 Cohesin-mediated genome architecture does not define DNA replication timing domains

Oldach, P.; Nieduszynski, C. A.

10.1101/542902 — molecular biology — Posted on 2019-02-06

2229 Epigenetic inhibitors sensitize DLBCL cells to rituximab and doxorubicin

Facciotto, C.; Casado, J.; Turunen, L.; Leivonen, S.-K.; Tumiati, M.; Rantanen, V.; Kauppi, L.; Lehtonen, R.; Leppä, S.; Wennerberg, K.; Hautaniemi, S.

10.1101/538199 — cancer biology — Posted on 2019-02-06

2230 Seasonal synchronization of sleep timing in industrial and pre-industrial societies: the regulating role of Daylight Saving Time

Martin-Olalla, J. M.

10.1101/392035 — physiology — Posted on 2019-02-06

2231 Quasiperiodic Rhythms of the Inferior Olive

Negrello, M.; Warnaar, P.; Romano, V.; Owens, C. B.; Lindeman, S.; Iavarone, E.; Spanke, J. K.; Bosman, L.; De Zeeuw, C.

10.1101/408112 — neuroscience — Posted on 2019-02-06

2232 Reelin Mediates Hippocampal Cajal-Retzius Cell Positioning and Infrapyramidal Blade Morphogenesis

Ha, S. R.; Tripathi, P.; Daza, R.; Hevner, R.; Beier, D. R.

10.1101/543074 — neuroscience — Posted on 2019-02-06

2233 No clear monogenic links between left-handedness and situs inversus

Postema, M. C.; Carrion-Castillo, A.; Fisher, S. E.; Vingerhoets, G.; Francks, C.

10.1101/422964 — genetics — Posted on 2019-02-06

2234 Freshwater diatoms diversify and turn over faster than marine in both planktonic and benthic habitats

Nakov, T.; Beaulieu, J. M.; Alverson, A. J.

10.1101/406165 — evolutionary biology — Posted on 2019-02-06

2235 Conformational switching of CD81 controls its function as a receptor for hepatitis C virus

Palor, M.; Stejskal, L.; Mandal, P.; Shepherd, A. J.; Grove, J.

10.1101/542837 — molecular biology — Posted on 2019-02-06

2236 Neandertal signatures in modern human mitochondrial genome haplogroups?

Ferreira, R. C.; Rodrigues, C. R.; Broach, J. R.; Briones, M. R.

10.1101/190363 — genomics — Posted on 2019-02-06

2237 Firing rate distributions in spiking networks with heterogeneous connectivity

Vegue, M.; Roxin, A.

10.1101/542456 — neuroscience — Posted on 2019-02-06

2238 Drift-diffusion models for multiple-alternative forced-choice decision making

Roxin, A.

10.1101/542431 — neuroscience — Posted on 2019-02-06

2239 Transcriptome Dedifferentiation Observed in Animal Primary Cultures is Essential to Plant Reprogramming

Ogata, N.

10.1101/542647 — plant biology — Posted on 2019-02-06

2240 HydroShoot: a functional-structural plant model for simulating hydraulic structure, gas and energy exchange dynamics of complex plant canopies under water deficit - application to grapevine (Vitis vinifera L.)

Albasha, R.; Fournier, C.; Pradal, C.; Chelle, M.; Prieto, J.; Louarn, G.; Simonneau, T.; Lebon, E.

10.1101/542803 — plant biology — Posted on 2019-02-06

2241 NADPH-oxidase 2 is required for molecular adaptations to high-intensity interval training in skeletal muscle.

Henriquez-Olguin, C.; Baghersad Renani, L.; Arab-Ceschia, L.; Raun, S. H.; Bhatia, A.; Li, Z.; Knudsen, J. R.; Holmdahl, R.; Jensen, T.

10.1101/542514 — physiology — Posted on 2019-02-06

2242 Relationships between depressive symptoms and brain responses during emotional movie viewing emerge in adolescence

Gruskin, D. C.; Rosenberg, M. D.; Holmes, A. J.

10.1101/542720 — neuroscience — Posted on 2019-02-06

2243 MassComp, a lossless compressor for mass spectrometry data

Yang, R.; Chen, X.; Ochoa, I.

10.1101/542894 — bioinformatics — Posted on 2019-02-06

2244 Weak Coupling Between Intracellular Feedback Loops Explains Dissociation of Clock Gene Dynamics

Schmal, C.; Ono, D.; Myung, J.; Pett, J. P.; Honma, S.; Honma, K.-I.; Herzel, H.; Tokuda, I. T.

10.1101/542852 — systems biology — Posted on 2019-02-06

2245 The exotic species Senecio inaequidens pays the price for arriving late in temperate European grasslands

Delory, B.; Weidlich, E. W. A.; Kunz, M.; Neitzel, J.; Temperton, V.

10.1101/542563 — ecology — Posted on 2019-02-06

2246 Rapid and Active Stabilization of Visual Cortical Firing Rates Across Light-Dark Transitions

Turrigiano, G. G.; Torrado Pacheco, A.; Tilden, E. I.; Gruztner, S. M.; Lane, B.; Wu, Y.; Hengen, K. B.; Gjorgjieva, J.

10.1101/542670 — neuroscience — Posted on 2019-02-06

2247 TCRGP: Determining epitope specificity of T cell receptors

Jokinen, E.; Heinonen, M.; Huuhtanen, J.; Mustjoki, S.; Lähdesmäki, H.

10.1101/542332 — bioinformatics — Posted on 2019-02-06

2248 Mammogram Segmentation using Multi-atlas Deformable Registration

Sharma, M. K.; Jas, M.; Karale, V.; Sadhu, A.; Mukhopadhyay, S.

10.1101/542217 — bioinformatics — Posted on 2019-02-06

2249 Network-specific synchronization of electrical slow-wave oscillations regulates sleep in Drosophila

Raccuglia, D.; Huang, S.; Ender, A.; Heim, M.-M.; Laber, D.; Liotta, A.; Sigrist, S. J.; Geiger, J. R. P.; Owald, D.

10.1101/542498 — neuroscience — Posted on 2019-02-06

2250 Model systems for large scale ecological research: parva sub ingenti

Wiersma, Y.; Wigle, R. D.; McMullin, R. T.

10.1101/542985 — ecology — Posted on 2019-02-06

2251 Multiscale model of integrin adhesion assembly

Bidone, T. C.; Skeeters, A. V.; Oakes, P. W.; Voth, G. A.

10.1101/542266 — biophysics — Posted on 2019-02-06

2252 Optical Metabolic Imaging of Heterogeneous Drug Response in Pancreatic Cancer Patient Organoids

Sharick, J. T.; Walsh, C. M.; Sprackling, C. M.; Pasch, C. A.; Parikh, A. A.; Matkowskyj, K. A.; Deming, D. A.; Skala, M. C.

10.1101/542167 — bioengineering — Posted on 2019-02-06

2253 Essential role of the mouse synapse associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance

R. von Collenberg, C.; Schmitt, D.; Ruelicke, T.; Sendtner, M.; Blum, R.; Buchner, E.

10.1101/542829 — animal behavior and cognition — Posted on 2019-02-06

2254 Protein appetite drives neural activity in the ventral tegmental area

Chiacchierini, G.; Naneix, F.; Peters, K. Z.; Snoeren, E. M.; McCutcheon, J.

10.1101/542340 — neuroscience — Posted on 2019-02-06

2255 Senescence-associated metabolomic phenotype in primary and iPSC-derived mesenchymal stromal cells

Fernandez-Rebollo, E.; Franzen, J.; Hollmann, J.; Ostrowska, A.; Oliverio, M.; Sieben, T.; Rath, B.; Kornfeld, J.-W.; Wagner, W.

10.1101/542357 — cell biology — Posted on 2019-02-06

2256 Prediction of Four Novel SNPs V17M, R11H, A66T, and F57S in the SBDS Gene Possibly Associated with Formation of Shwachman-Diamond Syndrome, using an Insilico Approach

Sati, A. O. M.; Ali, S. A. A.; Abduallah, R. B. A.; Elsied, M. S. A.; Salih, M. A.

10.1101/542654 — bioinformatics — Posted on 2019-02-06

2257 ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Even, A.; Morelli, G.; Scaramuzzino, C.; Gladwyn-Ng, I.; Le Bail, R.; Shilian, M.; Freeman, S.; Magiera, M. M.; AS, J.; Malgrange, B.; Brone, B.; Dietrich, P.; Dragatsis, I.; Janke, C.; Saudou, F.; Weil, M.; Nguyen, L.

10.1101/542464 — neuroscience — Posted on 2019-02-06

2258 A cross-species assessment of cognitive flexibility in compulsive disorders

Benzina, N.; N'Diaye, K.; Pelissolo, A.; Mallet, L.; Burguiere, E.

10.1101/542100 — neuroscience — Posted on 2019-02-06

2259 Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases

Perez-Jimenez, M. M.; Sansigre, P.; Valladares, A.; Venegas-Caleron, M.; Sanchez-Garcia, A.; Monje, J. M.; Esteban-Garcia, S.; Suarez-Pereira, I.; Vitorica, J.; Rios, J. J.; Artal-Sanz, M.; Carrion, A. M.; Munoz, M. J.

10.1101/541730 — developmental biology — Posted on 2019-02-06

2260 Developmental time course of SNAP-25 isoform regulation of hippocampal long-term synaptic plasticity and hippocampus-dependent learning

Gopaul, K. R.; Irfan, M.; Miry, O.; Vose, L. R.; Moghadam, A. A.; Hökfelt, T.; Bark, C.; Stanton, P. K.

10.1101/542928 — neuroscience — Posted on 2019-02-06

2261 A primer genetic toolkit for exploring mitochondrial biology and disease using zebrafish

Sabharwal, A.; Campbell, J. M.; WareJoncas, Z.; Wishman, M.; Ata, H.; Liu, W.; Ichino, N.; Bergren, J. D.; Urban, M. D.; Urban, R.; Poshusta, T. L.; Ding, Y.; Xu, X.; Clark, K. J.; Ekker, S. C.

10.1101/542084 — molecular biology — Posted on 2019-02-06

2262 Borrelia burgdorferi 297 bmpA encode the mRNA that contains ORF for a leader peptide that regulates bmpA gene expression.

Dubytska, L.

10.1101/542589 — molecular biology — Posted on 2019-02-06

2263 A mixed nitrogen diet and compartmentalized utilization for Mycobacterium tuberculosis replicating in host cells: results of a systems-based analysis

Borah, K.; Beyss, M.; Theorell, A.; Wu, H.; Basu, P.; Mendum, T.; Noh, K.; Beste, D.; McFadden, J.

10.1101/542480 — microbiology — Posted on 2019-02-06

2264 Estimating the abundance of benthic macrofauna from across shore transects

Totterman, S.

10.1101/542258 — ecology — Posted on 2019-02-06

2265 Distinct metabolic states of a cell guide alternate fates of mutational buffering through altered proteostasis

Verma, K.; Saxena, K.; Donaka, R.; Chaphalkar, A.; Rai, M. K.; Shukla, A.; Zaidi, Z.; Dandage, R.; Shanmugam, D.; Chakraborty, K.

10.1101/540039 — biochemistry — Posted on 2019-02-06

2266 Auxin export from proximal fruits drives arrest in competent inflorescence meristems

Ware, A.; Walker, C. H.; Simura, J.; Ljung, K.; Bishopp, A.; Wilson, Z. A.; Bennett, T.

10.1101/542662 — plant biology — Posted on 2019-02-06

2267 Electrically induced bacterial membrane potential dynamics correspond to cellular proliferation capacity

Stratford, J. P.; Edwards, C. L.; Ghanshyam, M. J.; Malyshev, D.; Delise, M. A.; Hayashi, Y.; Asally, M.

10.1101/542746 — microbiology — Posted on 2019-02-06

2268 Inhibitor of apoptosis, IAP, genes play a critical role in the survival of HIV-infected macrophages

Kumar, A.; Caballero, R. E. H.; Dong, S. X. M.; Gajanayaka, N.; Ali, H.; Cassol, E.; Cameron, W.; Korneluk, R.; Tremblay, M.; Angel, J.

10.1101/543017 — immunology — Posted on 2019-02-06

2269 Remarkable genetic diversity of Trypanosoma cruzi and Trypanosoma rangeli in two localities of southern Ecuador identified via deep sequencing of mini-exon gene amplicons

Maiguashca Sanchez, J.; Sueto, S. O. B.; Schwabl, P.; Grijalva, M. J.; Llewellyn, M. S.; Costales, J. A.

10.1101/542993 — genetics — Posted on 2019-02-06

2270 Proximity labeling reveals novel interactomes in live Drosophila tissue

Mannix, K. M.; Starble, R. M.; Kaufman, R. S.; Cooley, L.

10.1101/542795 — cell biology — Posted on 2019-02-06

2271 A familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene affects brain energy production

Newman, M.; Hin, N.; Pederson, S. M.; Lardelli, M.

10.1101/542134 — neuroscience — Posted on 2019-02-06

2272 A viscoelastic nuclear model predicting mechanical memory and convergence rate of nuclear spreading as a function of stiffness

Perez-Calixto, D.; Vazquez-Victorio, G.; Hautefeuille, M.

10.1101/542274 — biophysics — Posted on 2019-02-06

2273 Processing cookies formulated with goat cream enriched with conjugated linoleic acid

COSTA, A. C. D. S.; Pereira, D.; Verissimo, C.; Bomfim, M.; Queiroga, R.; Madruga, M.; Alves, S.; Bessa, R.; Oliveira, M.; Oliveira, J.

10.1101/542977 — biochemistry — Posted on 2019-02-06

2274 Structures of the Otopetrin Proton Channels Otop1 and Otop3

Saotome, K.; Teng, B.; Tsui, C. C.; Lee, W.-H.; Tu, Y.-H.; Sansom, M. S. P.; Liman, E. R.; Ward, A. B.

10.1101/542308 — biochemistry — Posted on 2019-02-06

2275 Fast and scalable genome-wide inference of local tree topologies from large number of haplotypes based on tree consistent PBWT data structure

Shchur, V.; Ziganurova, L.; Durbin, R.

10.1101/542035 — genomics — Posted on 2019-02-06

2276 The divergent effects of CDPPB and cannabidiol on fear extinction and anxiety in a predator scent stress model of PTSD in rats.

Shallcross, J.; Hamor, P.; Bechard, A.; Romano, M.; Knackstedt, L.; Schwendt, M.

10.1101/542118 — neuroscience — Posted on 2019-02-06

2277 Context-dependent selection as the keystone in somatic evolution of cancer

Watve, M.; Vibishan, B.

10.1101/542290 — cancer biology — Posted on 2019-02-06

2278 Deciphering the unique SNPs among leading Indian Tomato Cultivars using Double Digestion Restriction Associated DNA sequencing

Bodanapu, R.; Vasudevan, S. V.; Lekkala, S. P.; Chakravartty, N.; Lalam, K.; Kuriakose, B.; Bhanot, C.; Morey, P. N.; Katta, A. V. S. K. M.; Thomas, G.; Gupta, S.; Lachagari, V. B. R.

10.1101/541227 — genomics — Posted on 2019-02-06

2279 Sequence analysis allows functional annotation of tyrosine recombinases in prokaryotic genomes

Smyshlyaev, G.; Barabas, O.; Bateman, A.

10.1101/542381 — evolutionary biology — Posted on 2019-02-06

2280 Clonal plasma cells in AL amyloidosis are dependent on pro survival BCL-2 family proteins and sensitive to BH3 mimetics

Fraser, C.; Presser, A.; Sanchorawala, V.; Sarosiek, S.; Sarosiek, K.

10.1101/542159 — cancer biology — Posted on 2019-02-06

2281 Evolutionary rates are correlated between cockroach symbiont and mitochondrial genomes

Arab, D. A.; Bourguignon, T.; Wang, Z.; Ho, S. Y. W.; Lo, N.

10.1101/542241 — evolutionary biology — Posted on 2019-02-06

2282 Fuzzysplit: Demultiplexing and Trimming Sequenced DNA With a Declarative Language

Liu, D.

10.1101/534511 — bioinformatics — Posted on 2019-02-06

2283 Effects of enucleation on the direct reciprocal corticocortical connections between primary visual and somatosensory cortices of the mouse

Masse, I.; Bronchti, G.; Boire, D.

10.1101/515262 — neuroscience — Posted on 2019-02-06

2284 B cells engineered to express pathogen-specific antibodies using CRISPR/Cas9 protect against infection

Moffett, H. F.; Harms, C. K.; Fitzpatrick, K. S.; Tooley, M. R.; Boonyaratankornkit, J.; Taylor, J. J.

10.1101/541979 — immunology — Posted on 2019-02-06

2285 Crop residues in wheat-oilseed rape rotation system: a pivotal, shifting platform for microbial meetings

Kerdraon, L.; Balesdent, M.-H.; Barret, M.; Laval, V.; Suffert, F.

10.1101/456178 — microbiology — Posted on 2019-02-06

2286 Rare variants imputation in admixed populations: Comparison across reference panels and bioinformatics tools.

Sariya, S.; Lee, J.; Mayeux, R.; Vardarajan, B. N.; Reyes-Dumeyer, D.; Manly, J.; Brickman, A.; Lantigua, R.; Medrano, M.; Jimenez-Velazquez, I. Z.; Tosto, G.

10.1101/494229 — bioinformatics — Posted on 2019-02-05

2287 The simulation extrapolation technique meets ecology and evolution: A general and intuitive method to account for measurement error

Ponzi, E.; Keller, L. F.; Muff, S.

10.1101/535054 — evolutionary biology — Posted on 2019-02-05

2288 Design and characterisation of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems

Harding, R. J.; Loppnau, P.; Ackloo, S.; Lemak, A.; Hutchinson, A.; Hunt, B.; Holehouse, A.; Ho, J.; Fan, L.; Toledo-Sherman, L.; Seitova, A.; Arrowsmith, C.

10.1101/492215 — biochemistry — Posted on 2019-02-05

2289 Multiomic definition of generalizable endotypes in human acute pancreatitis.

Neyton, L.; Zheng, X.; Skouras, C.; Wilson, A. B.; Gutmann, M. U.; Yau, C.; Uings, I. J.; Rao, F. V.; Nicolas, A.; Marshall, C.; Wilson, L.-M.; Baillie, J. K.; Mole, D. J.

10.1101/539569 — systems biology — Posted on 2019-02-05

2290 Opposing Influence of Sensory and Motor Cortical Input on Striatal Circuitry and Choice Behavior

Lee, C. R.; Yonk, A. J.; Wiskerke, J.; Paradiso, K. G.; Tepper, J. M.; Margolis, D. J.

10.1101/446708 — neuroscience — Posted on 2019-02-05

2291 Electrical coupling controls dimensionality and chaotic firing of inferior olive neurons

Hoang, H.; Lang, E. J.; Hirata, Y.; Tokuda, I. T.; Aihara, K.; Toyama, K.; Kawato, M.; Schweighofer, N.

10.1101/542183 — neuroscience — Posted on 2019-02-05

2292 SPDI: Data Model for Variants and Applications at NCBI

Holmes, J. B.; Moyer, E.; Phan, L.; Maglott, D.; Kattman, B. L.

10.1101/537449 — genomics — Posted on 2019-02-05

2293 The TRAPP complex mediates secretion arrest induced by stress granule assembly

Zappa, F.; Wilson, C.; Di Tullio, G.; Santoro, M.; Pucci, P.; Monti, M.; D'Amico, D.; Pisonero Vaquero, S.; De Cegli, R.; Romano, A.; Saleem, M.; Polishchuk, E.; Failli, M.; Giaquinto, L.; De Matteis, M. A.

10.1101/528380 — cell biology — Posted on 2019-02-05

2294 Glass confers rhabdomeric photoreceptor identity in Drosophila, but not across all metazoans

Bernardo-Garcia, F. J.; Syed, M.; Jekely, G.; Sprecher, S. G.

10.1101/446161 — developmental biology — Posted on 2019-02-05

2295 Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM

Kalienkova, V.; Clerico Mosina, V.; Bryner, L.; Oostergetel, G. T.; Dutzler, R.; Paulino, C.

10.1101/455287 — biochemistry — Posted on 2019-02-05

2296 Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer

Schneider, B.; Boyer, A.; Ciccolini, J.; Barlesi, F.; Wang, K.; Benzekry, S.; Mochel, J. P.

10.1101/540849 — pharmacology and toxicology — Posted on 2019-02-05

2297 Repetitive mild concussion in subjects with a vulnerable cholinergic system: lasting cholinergic-attentional impairments in CHT+/- mice.

Koshy Cherian, A.; Tronson, N.; Parikh, V.; Kucinski, A.; Blakely, R.; Sarter, M.

10.1101/521484 — neuroscience — Posted on 2019-02-05

2298 Permutation methods for assessing significance in binary trait association mapping with structured samples

Mbatchou, J.; Abney, M.; McPeek, M. S.

10.1101/451377 — genetics — Posted on 2019-02-05

2299 Evolution of life cycles and reproductive traits: insights from the brown algae

Heesch, S.; Serrano-Serrano, M.; Luthringer, R.; Peters, A. F.; Destombe, C.; Cock, J. M.; Valero, M.; Roze, D.; Salamin, N.; coelho, s. m.

10.1101/530477 — evolutionary biology — Posted on 2019-02-05

2300 Genome plasticity in Papillomaviruses and de novo emergence of E5 oncogenes

Willemsen, A.; Felez-Sanchez, M.; Bravo, I. G.

10.1101/337477 — evolutionary biology — Posted on 2019-02-05

2301 Chk1 Phosphorylates Cdh1 to Promote SCFβTRCP-Dependent Degradation of Cdh1 During S-Phase

Pal, D.; Torres, A. E.; Messina, A. L.; Dickson, A.; De, K.; Willard, B.; Venere, M.; Summers, M. K.

10.1101/535799 — cell biology — Posted on 2019-02-05

2302 OPTIMIR, a novel algorithm for integrating available genome-wide genotype data into miRNA sequence alignment analysis.

Thibord, F.; Perret, C.; Roux, M.; Suchon, P.; Germain, M.; Deleuze, J.-F.; Morange, P.-E.; Tregouet, D.-A.

10.1101/479097 — bioinformatics — Posted on 2019-02-05

2303 Characterizing the Dynamical Complexity underlying Meditation

Escrichs, A.; Sanjuan, A.; Atasoy, S.; Lopez-Gonzalez, A.; Garrido, C.; Camara, E.; Deco, G.

10.1101/521963 — neuroscience — Posted on 2019-02-05

2304 Optogenetic and transcriptomic interrogation of enhanced muscle function in the paralyzed mouse whisker pad

Vajtay, T. J.; Bandi, A.; Upadhyay, A.; Swerdel, M. R.; Hart, R. P.; Lee, C. R.; Margolis, D. J.

10.1101/473298 — neuroscience — Posted on 2019-02-05

2305 Single synapse indicators of impaired glutamate clearance derived from fast iGluu imaging of cortical afferents in the striatum of normal and Huntington (Q175) mice

Dvorzhak, A.; Helassa, N.; Török, K.; Schmitz, D.; Grantyn, R.

10.1101/455758 — neuroscience — Posted on 2019-02-05

2306 Global increase in circRNA levels in myotonic dystrophy

Czubak, K.; Taylor, K.; Piasecka, A.; Sobczak, K.; Kozlowska, K.; Philips, A.; Sedehizadeh, S.; Brook, J. D.; Wojciechowska, M.; Kozlowski, P.

10.1101/489070 — molecular biology — Posted on 2019-02-05

2307 Lineage tracing analysis of cone photoreceptor-associated cis-regulatory elements in the developing chicken retina.

Schick, E.; McCaffery, S.; Keblish, E.; Thakurdin, C.; Emerson, M.

10.1101/531475 — developmental biology — Posted on 2019-02-05

2308 DisCVR: Rapid viral diagnosis from high-throughput sequencing data

Maabar, M.; Davison, A. J.; Thorburn, F.; Gunson, R.; Palmarini, M.; Hughes, J.

10.1101/527127 — bioinformatics — Posted on 2019-02-05

2309 Exploratory and prospective model of stent restenosis after Percutaneous Coronary Intervention using MultivariateGaussian Subspatial Regression

Vicente-Palacios, V.; Vicente-Tavera, S.; Dorado-Diaz, I.; Sanchez-Puente, A.; Sampedro-Gomez, J.; Galindo, P.; Gomez, I.; San Roman, J. A.; Fernandez-Aviles, F.; Sanchez, P. L.

10.1101/445361 — bioinformatics — Posted on 2019-02-05

2310 Differential regional decline in dopamine receptor availability across adulthood: Linear and nonlinear effects of age

Seaman, K. L.; Smith, C. T.; Juarez, E. J.; Dang, L. C.; Castrellon, J. J.; Burgess, L. L.; San Juan, M. D.; Kundzicz, P. M.; Cowan, R. L.; Zald, D. H.; Samanez-Larkin, G.

10.1101/358200 — neuroscience — Posted on 2019-02-05

2311 The winner takes it all: how semelparous insects can become periodical

Diekmann, O.; Planque, R.

10.1101/446252 — ecology — Posted on 2019-02-05

2312 Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations

Hayama, R.; Sorci, M.; Keating, J. J.; Hecht, L. M.; Plawsky, J. L.; Belfort, G.; Chait, B. T.; Rout, M. P.

10.1101/435651 — biophysics — Posted on 2019-02-05

2313 Poly-Enrich: Count-based Methods for Gene Set Enrichment Testing with Genomic Regions

Lee, C. T.; Cavalcante, R. G.; Lee, C.; Qin, T.; Patil, S.; Wang, S.; Tsai, Z. T.; Boyle, A. P.; Sartor, M. A.

10.1101/488734 — bioinformatics — Posted on 2019-02-05

2314 A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

Niepel, M.; Hafner, M.; Mills, C.; Subramanian, K.; Williams, E. H.; Chung, M.; Gaudio, B.; Barrette, A. M.; Stern, A. D.; Hu, B.; Korkola, J. E.; LINCS Consortium, ; Gray, J. W.; Birtwistle, M. R.; Heiser, L. M.; Sorger, P. K.

10.1101/213553 — cancer biology — Posted on 2019-02-05

2315 Manganese-induced Parkinsonism in mice is reduced using a novel contaminated water sediment exposure model.

Freeman, D. M.; O'Neal, R.; Zhang, Q.; Bouwer, E. J.; Wang, Z.

10.1101/541664 — pharmacology and toxicology — Posted on 2019-02-05

2316 An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns

Neidlin, M.; Chantzi, E.; Macheras, G.; Gustafsson, M.; Alexopoulos, L. G.

10.1101/541375 — bioengineering — Posted on 2019-02-05

2317 Conservation and flexibility in the gene regulatory landscape of Heliconiine butterfly wings

Hanly, J. J.; Wallbank, R. W.; McMillan, W. O.; Jiggins, C. D.

10.1101/541599 — evolutionary biology — Posted on 2019-02-05

2318 OCT4 expression regulated apoptosis and cell cycle in myeloma cells

Niknamian, S.

10.1101/497875 — cancer biology — Posted on 2019-02-05

2319 Will climate change affect sugar beet establishment of the 21st century? Insights from a simulation study using a crop emergence model

Lamichhane, J. R.; Constantin, J.; Aubertot, J.-N.; Durr, C.

10.1101/541276 — plant biology — Posted on 2019-02-05

2320 Ligand dependent gene regulation by transient ER clustered enhancers

Saravanan, B.; Soota, D.; Islam, Z.; Jayani, R. S.; Mann, R.; Farooq, U.; Meel, S.; Walavalkar, K.; Gayen, S.; Singh, A. K.; Hannenhalli, S.; Notani, D.

10.1101/541540 — molecular biology — Posted on 2019-02-05

2321 Emergence of stable coexistence in a complex microbial community through metabolic cooperation and spatio-temporal niche partitioning

Blasche, S.; Kim, Y.; Mars, R.; Kafkia, E.; Maansson, M.; Machado, D.; Teusink, B.; Nielsen, J.; Benes, V.; Neves, R.; Sauer, U.; Patil, K. R.

10.1101/541870 — microbiology — Posted on 2019-02-05

2322 Caribbean multi-centre study of Klebsiella pneumoniae: whole genome sequencing, antimicrobial resistance and virulence factors.

Heinz, E.; Brindle, R.; Morgan-McCalla, A.; Peters, K.; Thomson, N. R.

10.1101/541136 — genomics — Posted on 2019-02-05

2323 GNI-A1 mediates trade-off between grain number and grain weight in tetraploid wheat

Golan, G.; Ayalon, I.; Perry, A.; Zimran, G.; Ade-Ajayi, T.; Mosquna, A.; Distelfeld, A.; Peleg, Z.

10.1101/540096 — plant biology — Posted on 2019-02-05

2324 Coherence of Microcystis species revealed through population genomics

Perez-Carrascal, O. M.; Terrat, Y.; Giani, A.; Fortin, N.; Greer, C. W.; Tromas, N.; Shapiro, B. J.

10.1101/541755 — microbiology — Posted on 2019-02-05

2325 Intraspecific Variation in Microsatellite Mutation Profiles in Daphnia magna

Ho, E. K. H.; Macrae, F.; Latta, L. C.; Benner, M. J.; Sun, C.; Ebert, D.; Schaack, S.

10.1101/540773 — genomics — Posted on 2019-02-05

2326 Validation of genome-wide polygenic risk scores for coronary artery disease in French Canadians

Wünnemann, F.; Lo, K. S.; Langford-Avelar, A.; Busseuil, D.; Dube, M.-P.; Tardif, J.-C.; Lettre, G.

10.1101/538470 — genetics — Posted on 2019-02-05

2327 Domain-relevant auditory expertise modulates the additivity of neural mismatch responses in humans

Hansen, N. C.; Hojlund, A.; Moller, C.; Pearce, M.; Vuust, P.

10.1101/541037 — neuroscience — Posted on 2019-02-05

2328 Fingerprinting Adiposity and Metabolic Function in the Brains of Overweight and Obese Humans

Farruggia, M. C.; van Kooten, M. J.; Burke, M. V.; Scheinost, D.; Constable, R. T.; Small, D. M.

10.1101/540997 — neuroscience — Posted on 2019-02-05

2329 Emergence of hierarchical organization in memory for random material

Naim, M.; Katkov, M.; Recanatesi, S.; Tsodyks, M.

10.1101/541490 — neuroscience — Posted on 2019-02-05

2330 Gut microbiota influence B cell function in a TLR5-dependent manner

Ley, R.; Li, S.; Walters, W.; Chassaing, B.; Zhang, B.; Shi, Q.; Waters, J.; Gewirtz, A. T.; Leifer, C. A.

10.1101/537894 — immunology — Posted on 2019-02-05

2331 The functional landscape of the human phosphoproteome

Ochoa, D.; Jarnuczak, A. F.; Gehre, M.; Soucheray, M.; Kleefeldt, A. A.; Vieitez, C.; Hill, A.; Garcia-Alonso, L.; Swaney, D. L.; Vizcaino, J. A. A.; Noh, K.-M.; Beltrao, P.

10.1101/541656 — genomics — Posted on 2019-02-05

2332 Chemosymbiotic bivalves contribute to the nitrogen budget of seagrass ecosystems

Cardini, U.; Bartoli, M.; Lee, R.; Luecker, S.; Mooshammer, M.; Polzin, J.; Weber, M.; Petersen, J.

10.1101/537746 — ecology — Posted on 2019-02-05

2333 Neutral processes and high inter-annual turnover shape the assembly of soil bacterial communities in a Mediterranean watershed.

Tsiknia, M.; Fodelianakis, S.; Nikolaidis, N. P.; Paranychianakis, N. V.

10.1101/542076 — ecology — Posted on 2019-02-05

2334 Combining the 5.8S and ITS2 gene regions to improve classification of fungi

Heeger, F.; Wurzbacher, C.; Bourne, E. C.; Mazzoni, C. J.; Monaghan, M. T.

10.1101/532358 — ecology — Posted on 2019-02-05

2335 From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL

Liu, A.; Trairatphisan, P.; Gjerga, E.; Didangelos, A.; Barratt, J.; Saez-Rodriguez, J.

10.1101/541888 — systems biology — Posted on 2019-02-05

2336 Effects of high iodine containing low osmolar contrast agent (visipaque) on thyroid function tests

Niknamian, S.

10.1101/513291 — pathology — Posted on 2019-02-05

2337 SNIPE score can capture prodromal Alzheimer's in cognitively normal subjects

Zandifar, A.; Fonov, V.; Duchesne, S.; Potvin, O.; Collins, D. L.

10.1101/541854 — neuroscience — Posted on 2019-02-05

2338 Trypanosoma brucei ribonuclease H2A is an essential enzyme that resolves R-loops associated with transcription initiation and antigenic variation

Briggs, E. M.; Crouch, K.; Lemgruber, L.; Hamilton, G.; Lapsley, C.; McCulloch, R.

10.1101/541300 — microbiology — Posted on 2019-02-05

2339 Rectal swabs in critically-ill patients provide discordant representations of the gut microbiome compared to stool samples: a brief methodologic report.

Fair, K.; Dunlap, D. G.; Fitch, A.; Morris, A.; McVerry, B. J.; Kitsios, G.

10.1101/541441 — microbiology — Posted on 2019-02-05

2340 Stimulus-aware spatial filtering for single-trial neural response and temporal response function estimation in high-density EEG with applications in auditory research

Das, N.; Vanthornhout, J.; Francart, T.; Bertrand, A.

10.1101/541318 — neuroscience — Posted on 2019-02-05

2341 Structured event memory: a neuro-symbolic model of event cognition

Franklin, N.; Norman, K. A.; Ranganath, C.; Zacks, J. M.; Gershman, S. J.

10.1101/541607 — neuroscience — Posted on 2019-02-05

2342 Mutagenesis of orco impairs foraging but not oviposition in the hawkmoth Manduca sexta

Fandino, R. A.; Haverkamp, A.; Bisch-Knaden, S.; Zhang, J.; Bucks, S.; Nguyen Thi, T. A.; Werckenthin, A.; Ryback, J.; Stengl, M.; Knaden, M.; Hansson, B. S.; Grosse-Wilde, E.

10.1101/541201 — neuroscience — Posted on 2019-02-05

2343 Presence of Legionella spp. in cooling towers: the role of microbial diversity, Pseudomonas, and continuous chlorine application.

Paranjape, K.; Bedard, E.; Whyte, L. G.; Ronholm, J.; Prevost, M.; Faucher, S. P.

10.1101/540302 — microbiology — Posted on 2019-02-05

2344 Luliconazole, a New Antifungal, vs Amphotericin B, Voriconazole, Posaconazole and Caspofungin against Clinical and Environmental Aspergillus Nigri Complex

Hivary, S.; Fatahinia, M.; Halvaeezadeh, M.; Zarei Mahmoudabadi, A.

10.1101/541185 — microbiology — Posted on 2019-02-05

2345 Reproducible Risk Loci and Psychiatric Comorbidities in Anxiety: Results from ~200,000 Million Veteran Program Participants

Levey, D. F.; Gelernter, J.; Polimanti, R.; Zhou, H.; Cheng, Z.; Aslan, M.; Quaden, R.; Concato, J.; Radhakrishnan, K.; Bryois, J.; Sullivan, P. F.; the Million Veteran Program, ; Stein, M.

10.1101/540245 — genetics — Posted on 2019-02-05

2346 Seasonal changes of airborne bacterial communities over Tokyo and influence of local meteorology

Uetake, J.; Tobo, Y.; Uji, Y.; Hill, T. C. J.; DeMott, P. J.; Kreidenweis, S.; Misumi, R.

10.1101/542001 — ecology — Posted on 2019-02-05

2347 Epistasis Detection using Model-Based Multifactor Dimensionality Reduction in Structured Populations

Abegaz, F.; Van Lishout, F.; Mahachie John, J. M.; Chiachoompu, K.; Bhardwaj, A.; Gusareva, E. S.; Wei, Z.; Hakonarson, H.; Van Steen, K.

10.1101/541946 — bioinformatics — Posted on 2019-02-05

2348 Characterization of the workplace chemical exposome using untargeted LC-MS/MS: a case study

McCall, L.-I.; Anderson, V. M.; Fogle, R. S.; Haffner, J. J.; Hossain, E.; Liu, R.; Ly, A. H.; Ma, H.; Nadeem, M.; Yao, S.

10.1101/541813 — biochemistry — Posted on 2019-02-05

2349 Prediction of combination therapies based on topological modeling of the immune signaling network in Multiple Sclerosis

Bernardo-Faura, M.; Rinas, M.; Wirbel, J.; Pertsovskaya, I.; Pliaka, V.; Messinis, D. E.; Vila, G.; Sakellaropoulos, T.; Faigle, W.; Stridh, P.; Behrens, J. R.; Olsson, T.; Martin, R.; Paul, F.; Alexopoulos, L. G. G.; Villoslada, P.; Saez-Rodriguez, J.

10.1101/541458 — systems biology — Posted on 2019-02-05

2350 Integrating Biomedical Research and Electronic Health Records to Create Knowledge Based Biologically Meaningful Machine Readable Embeddings

Nelson, C. A.; Butte, A.; Baranzini, S. E.

10.1101/540963 — systems biology — Posted on 2019-02-05

2351 Comparative transcriptome analysis of Powdery mildew Resistance between two Melon (Cucumis melo L) with Different Thickness Peel

Hong, C.; Wei-ping, K.; Jun-Feng, L.

10.1101/541391 — plant biology — Posted on 2019-02-05

2352 Contextual effects on binocular matching are evident in primary visual cortex

Rideaux, R.; Welchman, A. E.

10.1101/541466 — neuroscience — Posted on 2019-02-05

2353 Performance of normative and approximate evidence accumulation on the dynamic clicks task

Radillo, A. E.; Veliz-Cuba, A.; Josic, K.; Kilpatrick, Z. P.

10.1101/541045 — neuroscience — Posted on 2019-02-05

2354 The effect of stimulus envelope shape on the auditory steady-state response

Van Canneyt, J.; Hofmann, M.; Wouters, J.; Francart, T.

10.1101/541359 — neuroscience — Posted on 2019-02-05

2355 A scalar Poincare map for struggling in Xenopus tadpoles

Olenik, M.; Houghton, C.

10.1101/540971 — neuroscience — Posted on 2019-02-05

2356 Cell entry-independent role for the reovirus μ1 protein in regulating necroptosis and the accumulation of viral gene products

Roebke, K. E.; Danthi, P.

10.1101/541623 — microbiology — Posted on 2019-02-05

2357 Immunization with recombinant enolase of Sporothrix spp (rSsEno) confers effective protection against sporotrichosis in mice

Portuondo Fuentes, D. L.; Dores-Silva, P. R.; Ferreira, L.; Tellez-Martinez, D.; Maria Marcos, C.; de Aguiar Loesch, M. L.; Guzman Quimbayo, F.; Cesar Borges, J.; Batista-Duharte, A.; Carlos, I. Z.

10.1101/541029 — immunology — Posted on 2019-02-05

2358 Deciphering the Genetics of Major End-Use Quality Traits in Wheat

Mohajeri Naraghi, S.; Simsek, S.; Kumar, A.; Al Rabbi, S. M. H.; S. Alamri, M.; Elias, E. M.; Mergoum, M.

10.1101/540831 — genetics — Posted on 2019-02-05

2359 Deep learning reveals cancer metastasis and therapeutic antibody targeting in whole body

Pan, C.; Schoppe, O.; Parra-Damas, A.; Cai, R.; Todorov, M. I.; Gondi, G.; von Neubeck, B.; Ghasemi, A.; Reimer, M. A.; Coronel, J.; Garvalov, B. K.; Menze, B.; Zeidler, R.; Erturk, A.

10.1101/541862 — cancer biology — Posted on 2019-02-05

2360 Detecting anomalies in RNA-seq quantification

Ma, C.; Kingsford, C.

10.1101/541714 — bioinformatics — Posted on 2019-02-05

2361 Efficient Electric Field Simulations for Transcranial Brain Stimulation

Bicalho Saturnino, G.; Madsen, K. H.; Thielscher, A.

10.1101/541409 — bioengineering — Posted on 2019-02-05

2362 Not all interactions are positive: testing how antagonistic interactions impact the robustness of plant-pollinator networks.

Briggs, H. M.; Ayers, C.; Armsworth, P.; Brosi, B.

10.1101/538702 — animal behavior and cognition — Posted on 2019-02-05

2363 Formalin Tissue Fixation Biases Myelin-Sensitive MRI

Seifert, A. C.; Umphlett, M.; Hefti, M.; Fowkes, M.; Xu, J.

10.1101/541631 — neuroscience — Posted on 2019-02-05

2364 The dynamics of the HIV-1 latent reservoir - considering the heterogeneous subpopulations

Ke, R.; Deng, K.

10.1101/541961 — microbiology — Posted on 2019-02-05

2365 A dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections

Baral, S.; Antia, R.; Dixit, N. M.

10.1101/540054 — immunology — Posted on 2019-02-05

2366 Characterization of prevalence and health consequences of uniparental disomy in four million individuals from the general population

Nakka, P.; Smith, S. P.; O'Donnell-Luria, A. H.; McManus, K. F.; 23andMe Research Team, ; Mountain, J. L.; Ramachandran, S.; Sathirapongsasuti, F.

10.1101/540955 — genomics — Posted on 2019-02-05

2367 Phylogenomics clarifies biogeographic and evolutionary history, and conservation status of West Indian tremblers and thrashers (Aves: Mimidae)

DaCosta, J. M.; Miller, M. J.; Mortensen, J. L.; Reed, J. M.; Curry, R. L.; Sorenson, M. D.

10.1101/540658 — evolutionary biology — Posted on 2019-02-05

2368 Predicting KIR Structural Haplotypes with Novel Sequence Signatures from Short-read Whole Genome Sequencing

Roe, D.; Kuang, R.

10.1101/541938 — bioinformatics — Posted on 2019-02-05

2369 VEF: a Variant Filtering tool based on Ensemble methods

Zhang, C.; Ochoa, I.

10.1101/540286 — bioinformatics — Posted on 2019-02-05

2370 Large scale automated phylogenomical analysis of bacterial whole-genome isolates and the Evergreen platform

Szarvas, J.; Ahrenfeldt, J.; Bellod Cisneros, J. L.; Thomsen, M. C. F.; Aarestrup, F. M.; Lund, O.

10.1101/540138 — bioinformatics — Posted on 2019-02-05

2371 Exploring the space of human exploration

Schulz, E.; Bertram, L.; Hofer, M.; Nelson, J. D.

10.1101/540666 — animal behavior and cognition — Posted on 2019-02-05

2372 Diet induces reproducible alterations in the mouse and human gut microbiome

Bisanz, J. E.; Upadhyay, V.; Turnbaugh, J. A.; Ly, K.; Turnbaugh, P. J.

10.1101/541797 — microbiology — Posted on 2019-02-05

2373 RAB1B interacts with TRAF3 to promote antiviral innate immunity

Beachboard, D. C.; Park, M.; Vijayan, M.; Fernando, D. J.; Williams, G. D.; Horner, S. M.

10.1101/542050 — immunology — Posted on 2019-02-05

2374 Trans-generational transcriptomic response to natural variation in host plant toxicity and insecticides in a specialist insect.

Birnbaum, S. S. L.; Abbot, P.

10.1101/541904 — genomics — Posted on 2019-02-05

2375 Adaptation to drought is coupled with slow growth in marginal silver fir (Abies alba Mill.) populations

Csillery, K.; Buchmann, N.; Fady, B.

10.1101/531806 — evolutionary biology — Posted on 2019-02-05

2376 MoMI-G: Modular Multi-scale Integrated Genome Graph Browser

Yokoyama, T. T.; Sakamoto, Y.; Seki, M.; Suzuki, Y.; Kasahara, M.

10.1101/540120 — bioinformatics — Posted on 2019-02-05

2377 Link Your Sites (LYS) Scripts: Automated search of protein structures and mapping of sites under positive selection detected by PAML

Sanz Moreta, L.; da Fonseca, R.

10.1101/540229 — bioinformatics — Posted on 2019-02-05

2378 The structure of a highly conserved picocyanobacterial protein reveals a Tudor domain with a novel tRNA binding function

Bauer, K. M.; Dicovitsky, R.; Pellegrini, M.; Zhaxybayeva, O.; Ragusa, M. J.

10.1101/542068 — biochemistry — Posted on 2019-02-05

2379 Audiograms of howling monkeys: are extreme loud calls the result of runaway selection?

Ramsier, M. A.; Cunningham, A. J.; Patino, M. R.; Glander, K. E.; Dominy, N. J.

10.1101/539023 — animal behavior and cognition — Posted on 2019-02-05

2380 Single-cell determination of iron content in magnetotactic bacteria: implications for the iron biogeochemical cycle

Amor, M.; Tharaud, M.; Gelabert, A.; Komeili, A.

10.1101/541953 — microbiology — Posted on 2019-02-05

2381 Energy-dependent transport at dural lymphatic vessels is necessary for Aβ brain clearance in Alzheimer's disease

Romanova, L.; Philips, H.; Calip, G.; Hauser, K.; Peterson, D.; Lazarov, O.; Predescu, D.; Predescu, S.; Schneider, J.; Kordower, J.; Hansen, E.; Lam, C.; Janson, C.

10.1101/427617 — biochemistry — Posted on 2019-02-05

2382 A data-driven approach to selecting invited speakers at conferences: a step toward gender parity

Vallence, A.-M.; Hinder, M. R.; Fujiyama, H.

10.1101/426320 — scientific communication and education — Posted on 2019-02-05

2383 Effects of Δ9-tetrahydrocannabinol (THC) vapor inhalation in Sprague-Dawley and Wistar rats

Taffe, M. A.; Creehan, K. M.; Vandewater, S. A.; Kerr, T. M.; Cole, M.

10.1101/541003 — pharmacology and toxicology — Posted on 2019-02-05

2384 Hybrid misexpression in multiple developing tissues within a recent adaptive radiation of Cyprinodon pupfishes

McGirr, J. A.; Martin, C. H.

10.1101/372912 — evolutionary biology — Posted on 2019-02-05

2385 Tumor establishment requires tumor autonomous and non autonomous decoupling of EGF signaling from apoptosis

Ngo, S.; Liang, J.; O'Brien, L. E.

10.1101/541912 — developmental biology — Posted on 2019-02-05

2386 Improving drug discovery using image-based multiparametric analysis of epigenetic landscape.

Farhy, C.; Orozco, L.; Zeng, F.-Y.; Pass, I.; Hariharan, S.; Ylanko, J.; Huang, C.-T.; Andrews, D.; Terskikh, A.

10.1101/541151 — cell biology — Posted on 2019-02-05

2387 Human Visuomotor Decision Making Under Risk is Not Optimally Adapted to Movement Variability

Adkins, T. J.; Lewis, R. L.; Lee, T. G.

10.1101/406439 — animal behavior and cognition — Posted on 2019-02-05

2388 Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening

Lee, O. W.; Austin, S. M.; Gamma, M. R.; Cheff, D. M.; Lee, T. D.; Wilson, K. M.; Johnson, J. M.; Travers, J. C.; Braisted, J. C.; Guha, R.; Klumpp-Thomas, C.; Shen, M.; Hall, M. D.

10.1101/404665 — cell biology — Posted on 2019-02-05

2389 Towards a decision support tool for intensive care discharge: machine learning algorithm development using electronic health care data from MIMIC-III and Bristol, UK.

McWilliams, C.; Lawson, D. J.; Santos-Rodriguez, R.; Gilchrist, I. D.; Champneys, A.; Gould, T. H.; Thomas, M. J. C.; Bourdeaux, C. P.

10.1101/404533 — physiology — Posted on 2019-02-05

2390 Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages

Guo, M.; Hartlova, A.; Gierlinski, M.; Prescott, A.; Castellvi, J.; Hernandez Losa, J.; Petersen, S. K.; Wenzel, U. A.; D. Dill, B.; H. Emmerich, C.; Ramon y Cajal, S.; G. Russell, D.; Trost, M.

10.1101/382853 — immunology — Posted on 2019-02-05

2391 Iso-relevance Functions - A Systematic Approach to Ranking Genomic Features by Differential Effect Size

Nayak, S.; Lahens, N.; Kim, E. J.; Ricciotti, E.; Paschos, G.; Tishkoff, S.; Sarantopoulou, D.; Sengupta, S.; Cooperman, B.; Grosser, T.; Grant, G.

10.1101/381814 — bioinformatics — Posted on 2019-02-05

2392 DataRemix: a universal data transformation for optimal inference from gene expression datasets

Mao, W.; Hausler, R.; Chikina, M.

10.1101/357467 — genomics — Posted on 2019-02-05

2393 EWI-2 Inhibits Cell-Cell Fusion at the Virological Presynapse

Whitaker, E. E.; Symeonides, M.; Munson, P. B.; Thali, M.

10.1101/296251 — microbiology — Posted on 2019-02-05

2394 Seidr: a gene meta-network calculation toolkit

Schiffthaler, B.; Serrano, A.; Delhomme, N.; Street, N. R.

10.1101/250696 — bioinformatics — Posted on 2019-02-05

2395 The potential role of collagens in congenital Zika syndrome: A systems biology approach

Aguiar, R. S.; Pohl, F.; Morais, G. L.; Nogueira, F. C.; Carvalho, J. B.; Guida, L.; Arge, L. W.; Melo, A.; Moreira, M. E.; Cunha, D. P.; Gomes, L.; Portari, E. A.; Velasquez, E.; Melani, R. D.; Pezzuto, P.; Castro, F. L.; Geddes, V. E.; Gerber, A. L.; Azevedo, G. S.; Schamber-Reis, B. L.; Goncalves, A. L.; Junqueira-de-Azevedo, I.; Nishiyama-Jr, M. Y.; Ho, P. L.; Schanoski, A. S.; Schuch, V.; Tanuri, A.; Chimelli, L.; Vasconcelos, Z. F.; Domont, G. B.; Vasconcelos, A. T.; Nakaya, H. I.

10.1101/541268 — systems biology — Posted on 2019-02-05

2396 Identification of Complex Multidimensional Patterns in Microbial Communities

Golovko, G.; Khanipov, K.; Albayrak, L.; Fofanov, Y.

10.1101/540815 — bioinformatics — Posted on 2019-02-05

2397 Deep convolutional and recurrent neural networks for cell motility discrimination and prediction

Kimmel, J.; Brack, A.; Marshall, W. F.

10.1101/159202 — bioinformatics — Posted on 2019-02-05

2398 Plant-microbe specificity varies as a function of elevation

Cobian, G. M.; Egan, C.; Amend, A. S.

10.1101/540799 — ecology — Posted on 2019-02-05

2399 Molecular mechanism of the chitinolytic monocopper peroxygenase reaction

Bissaro, B.; Streit, B.; Isaksen, I.; Eijsink, V. G. H.; Beckham, G. T.; DuBois, J.; Rohr, A. K.

10.1101/541292 — biochemistry — Posted on 2019-02-05

2400 Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer

Schneider, B.; Boyer, A.; Ciccolini, J.; Barlesi, F.; Wang, K.; Benzekry, S.; Mochel, J. P.

10.1101/540849 — pharmacology and toxicology — Posted on 2019-02-05

2401 Cue-selective adaptation operates on a separable encoding of stereo and texture information

Cesanek, E.; Domini, F.

10.1101/540260 — neuroscience — Posted on 2019-02-05

2402 Unmasking of novel mutations within XK gene that could be used as Diagnostic Markers to Predict McLeod syndrome: Using in silico analysis

Mustafa, M. I.; Hassan, M. A.

10.1101/540153 — bioinformatics — Posted on 2019-02-05

2403 Revealing neural correlates of behavior without behavioral measurements

Rubin, A.; Sheintuch, L.; Brande-Eilat, N.; Pinchasof, O.; Rechavi, Y.; Geva, N.; Ziv, Y.

10.1101/540195 — neuroscience — Posted on 2019-02-05

2404 Sulfur-oxidizing symbionts without canonical genes for autotrophic CO2 fixation

Seah, B.; Antony, C. P.; Huettel, B.; Zarzycki, J.; Schada von Borzyskowski, L.; Erb, T.; Kouris, A.; Kleiner, M.; Liebeke, M.; Dubilier, N.; Gruber-Vodicka, H.

10.1101/540435 — microbiology — Posted on 2019-02-05

2405 Different subtypes of influenza A viruses target different human proteins and pathways leading to different pathogenic phenotypes

Wang, Y.; Song, T.; Li, K.; Jin, Y.; Yue, J.; Ren, H.; Liang, L.

10.1101/541177 — microbiology — Posted on 2019-02-05

2406 DLITE: Dynamic Local Intercellular Tension Estimation

Vasan, R.; Maleckar, M. M.; Williams, C. D.; Rangamani, P.

10.1101/541144 — biophysics — Posted on 2019-02-05

2407 Making ATP fast and slow: do yeasts play a mixed strategy to metabolise glucose?

Safdari, H.; Sadeghi, M.; Kalirad, A.

10.1101/540757 — systems biology — Posted on 2019-02-05

2408 Spatial and temporal profiling of receptor membrane insertion controls commissural axon responses to midline repellents

Pignata, A.; Ducuing, H.; Boubakar, L.; Gardette, T.; Kindbeiter, K.; Bozon, M.; Tauszig-Delamasure, S.; Falk, J.; Thoumine, O.; Castellani, V.

10.1101/540690 — developmental biology — Posted on 2019-02-05

2409 Simultaneous tracking of cell motility in liquid and at the solid-liquid interface

Hook, A. L.; Flewellen, J. L.; Zaid, I. M.; Berry, R. M.; Dubern, J.-F.; Carabelli, A.; Wildman, R.; Russell, N.; Williams, P.; Alexander, M. R.

10.1101/541615 — biophysics — Posted on 2019-02-05

2410 Mechanistic Insights into Specific G Protein Interactions with Adenosine Receptors Revealed by Accelerated Molecular Simulations

Wang, J.; Miao, Y.

10.1101/541250 — biophysics — Posted on 2019-02-05

2411 Selfish: Discovery of Differential Chromatin Interactions via a Self-Similarity Measure

Roayaei Ardakany, A.; Ay, F.; Lonardi, S.

10.1101/540708 — bioinformatics — Posted on 2019-02-05

2412 Layer 5 circuits in V1 differentially control visuomotor behavior

Tang, L.; Higley, M. J.

10.1101/540807 — neuroscience — Posted on 2019-02-05

2413 Characterization of Pch2 localization determinants reveals a nucleolar- independent role in the meiotic recombination checkpoint

Herruzo, E.; Santos, B.; Freire, R.; Carballo, J.; San-Segundo, P.

10.1101/541367 — cell biology — Posted on 2019-02-05

2414 Deep protein methylation profiling by combined chemical and immunoaffinity approaches reveals novel PRMT1 targets

Hartel, N. G.; Chew, B.; Qin, J.; Xu, J.; Graham, N.

10.1101/538686 — systems biology — Posted on 2019-02-05

2415 Genetic variants disrupt human RGS14 binding to NHERF1 and regulation of NPT2A-mediated phosphate transport

Friedman, P. A.; Mamonova, T.; Magyar, C. E.; Squires, K. E.; Sneddon, W. B.; Emlet, D. R.; Hepler, J. R.

10.1101/540781 — pharmacology and toxicology — Posted on 2019-02-05

2416 Cranial anatomy of the predatory actinopterygian Brazilichthys macrognathus from the Permian (Cisuralian) Pedra de Fogo Formation, Parnaiba Basin, Brazil

Figueroa, R. T.; Friedman, M.; Gallo, V.

10.1101/540310 — paleontology — Posted on 2019-02-05

2417 Brain-enriched coding and long non-coding RNA genes are overrepresented in recurrent autism spectrum disorder CNVs

Alinejad-Rokny, H.; Heng, J.; Forrest, A.

10.1101/539817 — neuroscience — Posted on 2019-02-05

2418 Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells

Polak, M. E.; Sirvent, S.; Clayton, K.; Davies, J. D.; Vallejo, A. F.; Wu, Z.; Woo, J.; Riddell, J.; Stumpf, P. S.; Rose-Zerilli, M.; West, J.; Pujato, M.; Chen, X.; Woelk, C. H.; MacArthur, B. D.; Ardern-Jones, M. R.; Friedmanm, P. S.; Weirauch, M.; Singh, H.

10.1101/541383 — immunology — Posted on 2019-02-05

2419 HMGB1 as a rheostat of chromatin topology and RNA homeostasis on the path to senescence

Sofiadis, K.; Nikolic, M.; Zirkel, A.; Kargapolova, Y.; Josipovic, N.; Papadakis, A.; Gusmao, E.; Mizi, A.; Georgomanolis, T.; Koker, M.; Ullrich, R.; Altmueller, J.; Nuernberg, P.; Beyer, A.; Papantonis, A.

10.1101/540146 — genomics — Posted on 2019-02-05

2420 Quantitative prediction of enhancer-promoter interactions

Belokopytova, P.; Mozheiko, E.; Nuriddinov, M.; Fishman, D.; Fishman, V.

10.1101/541011 — genomics — Posted on 2019-02-05

2421 The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Onate, M.; Catenaccio, A.; Salvadores, N.; Saquel, C.; Martinez, A.; Moreno-Gonzalez, I.; Gamez, N.; Soto, P.; Soto, C.; Hetz, C.; Court, F. A.

10.1101/539700 — neuroscience — Posted on 2019-02-05

2422 Identification of a functional non-coding variant in the GABAA receptor α2 subunit of the C57BL/6J mouse reference genome: Major implications for neuroscience research

Mulligan, M. K.; Abreo, T.; Neuner, S. M.; Parks, C.; Watkins, C. E.; Houseal, M. T.; Shapaker, T. M.; Hook, M.; Tan, H.; Wang, X.; Ingels, J.; Peng, J.; Lu, L.; Kaczorowski, C. C.; Bryant, C. D.; Homanics, G. E.; Williams, R. W.

10.1101/540211 — genetics — Posted on 2019-02-05

2423 Low-dimensional Dynamics of Two Coupled Biological Oscillators

Droin, C.; Paquet, E. R.; Naef, F.

10.1101/541128 — systems biology — Posted on 2019-02-05

2424 A neurodevelopmental origin of behavioral individuality

Linneweber, G.; Andriatsilavo, M.; Dutta, S.; Hellbruegge, L.; Liu, G.; Ejsmont, R.; Fenk, L.; Straw, A.; Wernet, M.; Hiesinger, P. R.; Hassan, B.

10.1101/540880 — neuroscience — Posted on 2019-02-05

2425 A systems-based map of human brain cell-type enriched genes and malignancy-associated endothelial changes

Dusart, P.; Hallstrom, B. M.; Renne, T.; Odeberg, J.; Uhlen, M.; Butler, L.

10.1101/528414 — cell biology — Posted on 2019-02-05

2426 Reconstruction and Simulation of a Scaffold Model of the Cerebellar Network

Casali, S.; Marenzi, E.; Medini, C.; Casellato, C.; D'Angelo, E.

10.1101/532515 — neuroscience — Posted on 2019-02-05

2427 Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription.

Zhu, Y.; Huang, M.; Bushong, E.; Uytiepo, M.; EBeutter, E.; Boemer, D.; Ellisman, M.; Maximov, A.

10.1101/540856 — neuroscience — Posted on 2019-02-05

2428 Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal homeostasis and survival in Drosophila

Sharma, A.; Akagi, K.; Kapahi, P.; Pattavina, B.; Wilson, K. A.; Nelson, C.; Watson, M.; Maksoud, E.; Ortega, M.; Brem, R.

10.1101/540377 — molecular biology — Posted on 2019-02-05

2429 Transcriptional kinetics of X-chromosome upregulation

Larsson, A. J. M.; Coucoravas, C.; Sandberg, R.; Reinius, B.

10.1101/540104 — molecular biology — Posted on 2019-02-05

2430 Selection of Candida albicans Trisomy during Oropharyngeal Infection Results in a Commensal-Like Phenotype

Forche, A.; Solis, N. V.; Swidergall, M.; Thomas, R.; Guyer, A.; Beach, A.; Cromie, G. A.; Le, G. T.; Lowell, E.; Pavelka, N.; Berman, J.; Dudley, A.; Selmecki, A.; Filler, S.

10.1101/537340 — genomics — Posted on 2019-02-05

2431 Functional analysis of evolutionary human methylated regions in schizophrenia patients

Banerjee, N.; Polushina, T.; Stavrum, A.-K.; Steen, V. M.; Hellard, S. L.

10.1101/540294 — genomics — Posted on 2019-02-05

2432 The genetic determinants of the relative expression of alternative 3'UTR isoforms in human

Mariella, E.; Marotta, F.; Grassi, E.; Gilotto, S.; Provero, P.

10.1101/540088 — genetics — Posted on 2019-02-05

2433 Sex biased expression and co-expression networks in development, using the hymenopteran Nasonia vitripennis

Rago, A.; Werren, J. H.; Colbourne, J. K.

10.1101/540336 — evolutionary biology — Posted on 2019-02-05

2434 The landscape of the alternatively spliced transcriptome remains stable during aging across different species and tissues

Sieber, P.; Barth, E.; Marz, M.

10.1101/541417 — bioinformatics — Posted on 2019-02-05

2435 Design of a comprehensive microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protoplasts development and physiology

Sakai, K.; Charlot, F.; Le Saux, T.; Bonhomme, S.; Nogue, F.; Palauqui, J.-C.; Fattaccioli, J.

10.1101/526889 — plant biology — Posted on 2019-02-05

2436 Transmission of human-associated microbiota along family and social networks

Brito, I. L.; Gurry, T.; Zhao, S.; Huang, K.; Young, S.; Shea, T.; Naisilisili, W.; Jenkins, A.; Jupiter, S.; Gevers, D.; Alm, E. J.

10.1101/540252 — microbiology — Posted on 2019-02-05

2437 Comparative analysis of commercially available single-cell RNA sequencing platforms for their performance in complex human tissues

Wang, Y. J.; Schug, J.; Lin, J.; Wang, Z.; Kossenkov, A.; The HPAP Consortium, ; Kaestner, K. H.

10.1101/541433 — genomics — Posted on 2019-02-05

2438 Topological data analysis reveals principles of chromosome structure throughout cellular differentiation

Sauerwald, N.; Shen, Y.; Kingsford, C.

10.1101/540716 — genomics — Posted on 2019-02-05

2439 Oligogenic effects of 16p11.2 copy number variation on craniofacial development

Qiu, Y.; Arbogast, T.; Martin Lorenzo, S.; Li, H.; Shih, T.; Ellen, R.; Hong, O.; Cho, S.; Shanta, O.; Timothy, P.; Corsello, C.; Deutsch, C. K.; Chevalier, C.; Davis, E. E.; Iakoucheva, L. M.; Herault, Y.; Katasanis, N.; Messer, K.; Sebat, J.

10.1101/540732 — genetics — Posted on 2019-02-05

2440 Selectivity of Guanine Nucleotide Exchange Factor-mediated Cdc42 activation in primary human endothelial cells

Reinhard, N. R.; van der Niet, S.; Chertkova, A. O.; Postma, M.; Hordijk, P. L.; Gadella, T. W. J.; Goedhart, J.

10.1101/541219 — cell biology — Posted on 2019-02-05

2441 A charge-dependent phase transition determines interphase chromatin organization

Strickfaden, H.; Sharma, A. K.; Hendzel, M.

10.1101/541086 — cell biology — Posted on 2019-02-05

2442 The mechanistic basis for chromatin invasion and remodeling by the yeast pioneer transcription factor Rap1

Mivelaz, M.; Cao, A.-M.; Kubik, S.; Zencir, S.; Hovius, R.; Boichenko, I.; Stachowicz, A. M.; Kurat, C. F.; Shore, D.; Fierz, B.

10.1101/541284 — biophysics — Posted on 2019-02-05

2443 Dissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells using gene editing, RNAseq and proteomics

Younis, S.; Naboulsi, R.; Wang, X.; Cao, X.; Larsson, M.; Sargsyan, E.; Bergsten, P.; Welsh, N.; Andersson, L.

10.1101/540914 — molecular biology — Posted on 2019-02-05

2444 Endophilin-A controls recruitment, priming and fusion of neurosecretory vesicles

Milosevic, I.; Gowrisankaran, S.; Steubler, V.; Houy, S.; G. Pena del Castillo, J.; Gelker, M.; Kroll, J.; Pinheiro, P. S.; Halbsgut, N.; Raimundo, N.; Soerensen, J. B.

10.1101/540864 — neuroscience — Posted on 2019-02-05

2445 Energy-dependent transport at dural lymphatic vessels is necessary for Aβ brain clearance in Alzheimer's disease

Romanova, L.; Philips, H.; Calip, G.; Hauser, K.; Peteson, D.; Lazarov, O.; Predescu, D.; Predescu, S.; Schneider, J.; Kordower, J.; Hansen, E.; Lam, C.; Janson, C.

10.1101/427617 — biochemistry — Posted on 2019-02-05

2446 Anti-cancer property of Lenzites betulina (L) Fr. on cervical cancer cell lines and its anti-tumor effect on HeLa-implanted mice

Ghosh, S. K.; Sanyal, T.

10.1101/540567 — cancer biology — Posted on 2019-02-05

2447 A Community-based assessment of quality of health care received and client satisfaction in Lagos, Nigeria.

Akinyinka, M. R.; Oluwole, E. O.; Odusanya, O. O.

10.1101/541565 — epidemiology — Posted on 2019-02-05

2448 The seasonality of diarrheal pathogens: A retrospective study of seven sites over three years

Chao, D. L.; Roose, A.; Roh, M.; Kotloff, K. L.; Proctor, J. L.

10.1101/541581 — epidemiology — Posted on 2019-02-05

2449 Machine-learning to Improve Prediction of Mortality following Acute Myocardial Infarction: An Assessment in the NCDR-Chest Pain-Myocardial Infarction Registry

Khera, R.; Haimovich, J.; Hurley, N.; McNamara, R.; Spertus, J. A.; Desai, N.; Masoudi, F. A.; Huang, C.; Normand, S.-L.; Mortazavi, B. J.; Krumholz, H. M.

10.1101/540369 — bioinformatics — Posted on 2019-02-05

2450 Graph-to-Signal Transformation Based Classification of Functional Connectivity Brain Networks

Munia, T. T. K.; Aviyente, S.

10.1101/541532 — neuroscience — Posted on 2019-02-05

2451 Relationship between the Changes over Time of Bone and Muscle Health in Children and Adults: A Systematic Review and Meta-Analysis

Locquet, M.; Beaudart, C.; Durieux, N.; Reginster, J.-Y.; Bruyere, O.

10.1101/541524 — epidemiology — Posted on 2019-02-05

2452 Leptin and adiponectin dynamics at patients with rectal neoplasm - gender differences

Florescu, A.; Branisteanu, D.; Bilha, S.; Scripcariu, D.; Florescu, I.; Scripcariu, V.; Dimofte, G.; Grigoras, I.

10.1101/541557 — cancer biology — Posted on 2019-02-05

2453 Comparison of muscle activity, strength and balance, before and after a 6-month training using the FIFA11+ program (part 2)

Oshima, T.; Nakase, J.; Inaki, A.; Mochizuki, T.; Takata, Y.; Shimozaki, K.; Kinuya, S.; Tsuchiya, H.

10.1101/540492 — physiology — Posted on 2019-02-05

2454 A novel protocol for the isolation of fungal extracellular vesicles reveals the participation of a putative scramblase in polysaccharide export and capsule construction in Cryptococcus gattii.

Rodrigues, M.; Reis, F.; Borges, B.; Jozefowicz, L.; Sena, B.; Garcia, A. W. A.; Soares Medeiros, L. C.; Martins, S.; Honorato, L.; Schrank, A.; Vainstein, M. H.; Kmetzsch, L.; Nimrichter, L.; Alves, L.; Staats, C. C.

10.1101/538850 — microbiology — Posted on 2019-02-05

2455 PKA and HOG signaling contribute separable roles to anaerobic xylose fermentation in yeast engineered for biofuel production

Wagner, E.; Myers, K. S.; Riley, N. M.; Coon, J. J.; Gasch, A. P.

10.1101/540534 — genetics — Posted on 2019-02-05

2456 Aerobic bacteria as Escherichia coli can survive in ESwabTM medium after a 3 month-freezing at -80°C but not after multiple thawing

Rindala, S.; Jean-Ralph, Z.; Carbonnelle, E.; Lescat, M.

10.1101/537647 — microbiology — Posted on 2019-02-05

2457 Determinants of Self-referral among Outpatients at Referral Hospitals in East Wollega, Western Ethiopia

Geta, E. T.; Belete, Y. S.; Yesuf, E. A.

10.1101/540476 — epidemiology — Posted on 2019-02-05

2458 Microtubules stabilize intercellular contractile force transmission during tissue folding

Ko, C. S.; Tserunyan, V.; Martin, A.

10.1101/540344 — developmental biology — Posted on 2019-02-04

2459 An actin-based protrusion originating from a podosome-enrichedregion initiates macrophage fusion

Faust, J. J.; Balabiyev, A.; Heddleston, J. M.; Podolnikova, N. P.; Baluch, D. P.; Chew, T.-L.; Ugarova, T.

10.1101/538314 — cell biology — Posted on 2019-02-04

2460 Age-structure as key to delayed logistic proliferation of scratch assays

Ponce Bobadilla, A. V.; Carraro, T.; Byrne, H. M.; Maini, P. K.; Alarcon, T.

10.1101/540526 — cell biology — Posted on 2019-02-04

2461 Control of ΦC31 integrase-mediated site-specific recombination by protein trans splicing

Olorunniji, F. J.; Lawson-Williams, M.; McPherson, A. L.; Paget, J. E.; Stark, M.; Rosser, S. J.

10.1101/540872 — synthetic biology — Posted on 2019-02-04

2462 Nutrient transporter translocation to the plasma membrane via a Golgi-independent unconventional route

Bouris, V.; Martzoukou, O.; Amillis, S.; Diallinas, G.

10.1101/540203 — cell biology — Posted on 2019-02-04

2463 A Brownian ratchet model explains the biased sidestepping movement of single-headed kinesin-3 KIF1A

Mitra, A.; Sune, M.; Diez, S.; Sancho, J. M.; Oriola, D.; Casademunt, J.

10.1101/536250 — biophysics — Posted on 2019-02-04

2464 Revisiting tradeoffs in Rubisco kinetic parameters

Flamholz, A. I.; Prywes, N.; Moran, U.; Davidi, D.; Bar-On, Y.; Oltrogge, L.; Alves, R.; Savage, D.; Milo, R.

10.1101/470021 — systems biology — Posted on 2019-02-04

2465 Mouse trigeminal neurons respond to kokumi substances

Leijon, S. C. M.; Chaudhari, N.; Roper, S.

10.1101/540237 — neuroscience — Posted on 2019-02-04

2466 Sensorimotor adaptation compensates for distortions of 3D shape information

Cesanek, E.; Taylor, J. A.; Domini, F.

10.1101/540187 — neuroscience — Posted on 2019-02-04

2467 A competitive binding model predicts nonlinear responses of olfactory receptors to complex mixtures

Singh, V.; Murphy, N. R.; Balasubramanian, V.; Mainland, J. D.

10.1101/311514 — neuroscience — Posted on 2019-02-04

2468 The anterior insula channels prefrontal expectancy signals during affective processing

Teckentrup, V.; van der Meer, J. N.; Borchardt, V.; Fan, Y.; Neuser, M. P.; Tempelmann, C.; Herrmann, L.; Walter, M.; Kroemer, N. B.

10.1101/536300 — neuroscience — Posted on 2019-02-04

2469 UK phenomics platform for developing and validating EHR phenotypes: CALIBER

Denaxas, S.; Gonzalez-Izquierdo, A.; Direk, K.; Fitzpatrick, N.; Banerjee, A.; Dobson, R.; Fatemifar, G.; Kuan, V.; Lumbers, T.; Pasea, L.; Patel, R.; Hingorani, A.; Sudlow, C.; Hemingway, H.

10.1101/539403 — epidemiology — Posted on 2019-02-04

2470 Fine-scale family structure shapes influenza transmission risk in households: insights from a study of primary school students in Matsumoto city, 2014/15.

Endo, A.; Uchida, M.; Kucharski, A. J.; Funk, S.

10.1101/527507 — epidemiology — Posted on 2019-02-04

2471 AMMISOFT for AMMI Analysis with Best Practices

Gauch, H.; Moran, D. R.

10.1101/538454 — bioinformatics — Posted on 2019-02-04

2472 Fluorescence Microscopy of Piezo1 in Droplet Hydrogel Bilayers

Jaggers, O. B.; Ridone, P.; Martinac, B.; Baker, M. A.

10.1101/508176 — molecular biology — Posted on 2019-02-04

2473 Prescribing of different antibiotics, rates of bacteremia/septicemia and associated mortality in the US and England, and the utility of antibiotic replacement vs. reduction in prescribing

Goldstein, E.

10.1101/527101 — epidemiology — Posted on 2019-02-04

2474 Does closing the eyes enhance auditory attention? Eye closure increases attentional alpha-power modulation but not listening performance

Woestmann, M.; Schmitt, L.-M.; Obleser, J.

10.1101/455675 — neuroscience — Posted on 2019-02-04

2475 Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods

Wright, C.; Rajpurohit, A.; Burke, E. E.; Williams, C.; Collado-Torres, L.; Kimos, M.; Brandon, N. J.; Cross, A. J.; Jaffe, A. E.; Weinberger, D. R.; Shin, J. H.

10.1101/445437 — genomics — Posted on 2019-02-04

2476 The quiescent X, the replicative Y and the Autosomes

Achaz, G.; Gangloff, S.; Arcangioli, B.

10.1101/351288 — evolutionary biology — Posted on 2019-02-04

2477 Differential immune gene expression associated with contemporary range expansion of two invasive rodents in Senegal

Charbonnel, N.; Galan, M.; Tatard, C.; Loiseau, A.; Diagne, C. A.; Dalecky, A.; Parrinello, H.; Rialle, S.; Severac, D.; Brouat, C.

10.1101/442160 — ecology — Posted on 2019-02-04

2478 Parameter Identifiability and Non-Uniqueness in connectome based neural mass models

Xie, X.; Kuceyeski, A.; Shah, S. A.; Schiff, N. D.; Nagarajan, S.; Raj, A.

10.1101/480012 — neuroscience — Posted on 2019-02-04

2479 Transfer learning of deep neural network representations for fMRI decoding

Svanera, M.; Savardi, M.; Benini, S.; Signoroni, A.; Raz, G.; Hendler, T.; Muckli, L.; Goebel, R.; Valente, G.

10.1101/535377 — neuroscience — Posted on 2019-02-04

2480 Dashing: Fast and Accurate Genomic Distances with HyperLogLog

Baker, D. N.; Langmead, B.

10.1101/501726 — bioinformatics — Posted on 2019-02-04

2481 Visual closed-loop dynamics via ocular drift

Gruber, L. Z.; Ahissar, E.

10.1101/539445 — neuroscience — Posted on 2019-02-04

2482 Transient protein accumulation at the center of the T cell antigen presenting cell interface drives efficient IL-2 secretion

Clark, D. J.; McMillan, L. E.; Tan, S. L.; Bellomo, G.; Massoue, C.; Thompson, H.; Mykhaylechko, L.; Alibhai, D.; Ruan, X.; Singleton, K. L.; Du, M.; Hedges, A. J.; Schwartzberg, P. L.; Verkade, P.; Murphy, R. F.; Wülfing, C.

10.1101/296616 — immunology — Posted on 2019-02-04

2483 Accurate tracking of the mutational landscape of diploid hybrid genomes

Tattini, L.; Tellini, N.; Mozzachiodi, S.; D'Angiolo, M.; Loeillet, S.; Nicolas, A.; Liti, G.

10.1101/507830 — genomics — Posted on 2019-02-04

2484 Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei

Jiang, S.; Williams, K.; Kong, X.; Zeng, W.; Ma, X.; Tawil, R.; Yokomori, K.; Mortazavi, A.

10.1101/478636 — genomics — Posted on 2019-02-04

2485 Invasive Siberian chipmunks Eutamias sibiricus in Italy: a socio-ecological analysis indicates that they could, and should, be removed

Cerri, J.; Mori, E.; Zozzoli, R.; Gigliotti, A.; Chirco, A.; Bertolino, S.

10.1101/535088 — ecology — Posted on 2019-02-04

2486 Spatial resets modulate YAP-dependent transcription

Franklin, J. M.; Ghosh, R. P.; Shi, Q.; Liphardt, J. T.

10.1101/539049 — cell biology — Posted on 2019-02-04

2487 FUS controls the processing of snoRNAs into smaller RNA fragments that can regulate gene expression

Plewka, P.; Szczesniak, M.; Stepien, A.; Zywicki, M.; Pacak, A.; Colombo, M.; Makalowska, I.; Ruepp, M.-D.; Raczynska, K. D.

10.1101/409250 — molecular biology — Posted on 2019-02-04

2488 Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates

Shearn, R.; Lecompte, E.; Mousset, S.; Regis, C.; Penel, S.; Douay, G.; Crouau-Roy, B.; Marais, G.

10.1101/445072 — genomics — Posted on 2019-02-04

2489 Dynamics of microRNA expression during mouse prenatal development

Rahmanian, S.; Murad, R.; Breschi, A.; Zeng, W.; Williams, B. A.; Mackiewicz, M.; Roberts, B.; Meadows, S.; Moore, D.; Davis, C.; Trout, D.; Zaleski, C.; Dobin, A.; Sei, L.-H.; Drenkow, J.; Scavelli, A.; Gingeras, T. R.; Wold, B.; Myers, R. M.; Guigo, R.; Mortazavi, A.

10.1101/492918 — genomics — Posted on 2019-02-04

2490 Straightjacket/α 2δ 3 deregulation is associated with cardiac conduction defects in Myotonic Dystrophy type 1

Plantie, E.; Nakamori, M.; Renaud, Y.; Huguet, A.; Choquet, C.; Dondi, C.; Miquerol, L.; Takahashi, M.; Gourdon, G.; Junion, G.; Jagla, T.; Zmojdzian, M.; Jagla, K.

10.1101/431569 — genomics — Posted on 2019-02-04

2491 Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner

Yang, L. M.; Cheah, K. S. E.; Huh, S.-H.; Ornitz, D. M.

10.1101/436790 — developmental biology — Posted on 2019-02-04

2492 Genotypic and phenotypic diversity within the neonatal HSV-2 population

Akhtar, L. N.; Bowen, C. D.; Renner, D. W.; Pandey, U.; Della Fera, A. N.; Kimberlin, D. W.; Prichard, M. N.; Whitley, R. J.; Weitzman, M. D.; Szpara, M. L.

10.1101/262055 — microbiology — Posted on 2019-02-04

2493 Responses of ground-dwelling spider assemblages to changes in vegetation from wet oligotrophic habitats of Western France

Lafage, D.; Djoudi, E. A.; Perrin, G.; Gallet, S.; Petillon, J.

10.1101/380212 — ecology — Posted on 2019-02-04

2494 Ecdysone signaling promotes expression of multifunctional RNA binding proteins essential for ovarian germline stem cell self-renewal in Drosophila

Finger, D. S.; Holt, V. V.; Ables, E. T.

10.1101/321109 — developmental biology — Posted on 2019-02-04

2495 The selection arena in early human blastocysts resolves the pluripotent inner cell mass

Singh, M.; Widmann, T. J.; Bansal, V.; Cortes, J. L.; Schumann, G. G.; Wunderlich, S.; Martin, U.; Garcia-Perez, J. L.; Hurst, L. D.; Izsvak, Z.

10.1101/318329 — developmental biology — Posted on 2019-02-04

2496 An Event-Related Potential Study of Onset Primacy in Visual Change Detection

Van Pelt, J.; Donaldson, M. J.; Johnston, P.; Yamamoto, N.

10.1101/539932 — neuroscience — Posted on 2019-02-04

2497 Ecological advantages and evolutionary limitations of aggregative multicellular development

Pentz, J. T.; Marquez-Zacarias, P.; Yunker, P. J.; Libby, E.; Ratcliff, W. C.

10.1101/255307 — evolutionary biology — Posted on 2019-02-04

2498 Outcome of radial scar/complex sclerosing lesion associated with epithelial proliferations with atypia diagnosed on breast core biopsy - Results from a multicentric UK based study

Rakha, E.; Beca, F.; D'Andrea, M.; Abbas, A.; Petrou-Nunn, W.; Shaaban, A. M.; Kandiyil, A.; Smith, S.; Menon, S.; Elsheikh, S.; ElSayed, M. E.; Lee, A. H. S.; Sharma, N.

10.1101/538330 — pathology — Posted on 2019-02-04

2499 Early migration of precursor neurons initiates cellular and functional regeneration after spinal cord injury in zebrafish.

Vandestadt, C.; Vanwalleghem, G. C.; Castillo, H. A.; Li, M.; Schulze, K.; Khabooshan, M.; Don, E.; Anko, M.-L.; Scott, E. K.; Kaslin, J.

10.1101/539940 — neuroscience — Posted on 2019-02-04

2500 A New Experimental Model Of Muscle Pain In Humans Based On Short-Wave Diathermy

Mista, C. A.; Laugero, S.; Adur, J.; Andersen, O. K.; Biurrun Manresa, J.

10.1101/537878 — neuroscience — Posted on 2019-02-04

2501 EEG-based Prediction of Cognitive Load in Intelligence Tests

Friedman, N.; Fekete, T.; Gal, Y.; Shriki, O.

10.1101/539486 — neuroscience — Posted on 2019-02-04

2502 cyAbrB transcriptional regulators as safety devices to inhibit heterocyst differentiation in Anabaena

Higo, A.; Nishiyama, E.; Nakamura, K.; Hihara, Y.; Ehira, S.

10.1101/539908 — microbiology — Posted on 2019-02-04

2503 Targeted, High-Resolution RNA Sequencing Of Non-Coding Genomic Regions Associated With Neuropsychiatric Functions

Hardwick, S. A.; Bassett, S. D.; Kaczorowski, D.; Blackburn, J.; Barton, K.; Bartonicek, N.; Carswell, S. L.; Tilgner, H. U.; Loy, C.; Halliday, G.; Mercer, T. R.; Smith, M. A.; Mattick, J. S.

10.1101/539882 — genomics — Posted on 2019-02-04

2504 Supervised classification enables rapid annotation of cell atlases

Pliner, H. A.; Shendure, J.; Trapnell, C.

10.1101/538652 — genomics — Posted on 2019-02-04

2505 Novel hepatitis D-like agents in vertebrates and invertebrates

Chang, W.-S.; Pettersson, J. H.- O.; Le Lay, C.; Shi, M.; Lo, N.; Wille, M.; Eden, J.-S.; Holmes, E.

10.1101/539924 — evolutionary biology — Posted on 2019-02-04

2506 GWAS hints at pleiotropic roles for FLOWERING LOCUS T in flowering time and yield-related traits in canola

Raman, H.; Raman, R.; Qiu, Y.; Yadav, A. S. Y. S.; Sureshkumar, S.; Borg, L.; Maheswaran, R.; Wheeler, D.; Ovens, O.; Menz, I.; Balasubramanian, S.

10.1101/539890 — plant biology — Posted on 2019-02-04

2507 Root density sensing allows pro-active modulation of shoot growth to avoid future resource limitation

Wheeldon, C. D.; Walker, C. H.; Bennett, T.

10.1101/539726 — plant biology — Posted on 2019-02-04

2508 Estrogenic action by tris(2,6-dimethylphenyl) phosphate, an impurity in resorcinol bis flame retardant formulations, impairs the development of female reproductive functions

Sano, K.; Matsukami, H.; Suzuki, G.; Htike, N. T. T.; Morishita, M.; Win Shwe, T. T.; Hashimoto, S.; Kawashima, T.; Isobe, T.; Nakayama, S. F.; Tsukahara, S.; Maekawa, F.

10.1101/539395 — pharmacology and toxicology — Posted on 2019-02-04

2509 Predicting educational achievement from genomic measures and socioeconomic status

von Stumm, S.; Smith-Woolley, E.; Ayorech, Z.; McMillan, A.; Rimfeld, K.; Dale, P.; Plomin, R.

10.1101/538108 — genomics — Posted on 2019-02-04

2510 Polled Digital Cell Sorter (p-DCS): Automatic identification of hematological cell types from single cell RNA-sequencing clusters

Domanskyi, S.; Szedlak, A.; Hawkins, N. T.; Wang, J.; Paternostro, G.; Piermarocchi, C.

10.1101/539833 — bioinformatics — Posted on 2019-02-04

2511 Spatiotemporal dynamics of calcium transients during embryogenesis of Drosophila melanogaster

Markova, O.; Senatore, S.; Lenne, P.-F.

10.1101/540070 — developmental biology — Posted on 2019-02-04

2512 Cell non-autonomous interactions during non-immune stromal progression in the breast tumor microenvironment

Utama, R.; Bastian, A.; Sadagopan, N.; Jin, Y.; Antoniou, E.; Gao, Q.; Huang, Y. J.; Pillai, S.; Lee, P. P.; Atwal, G. S.

10.1101/540112 — cancer biology — Posted on 2019-02-04

2513 TIMP-1 attenuates the development of cutaneous inflammation-induced hypersensitivity

Knight, B. E.; Kozlowski, N.; Havelin, J.; King, T.; Crocker, S. J.; Young, E. E.; Baumbauer, K.

10.1101/540724 — neuroscience — Posted on 2019-02-04

2514 Experimental Evolution of the Megaplasmid pMPPla107 in Pseudomonas stutzeri Enables Identification of Genes Contributing to Sensitivity to an Inhibitory Agent

Smith, B. A.; Dougherty, K.; Clark, M.; Baltrus, D.

10.1101/538629 — microbiology — Posted on 2019-02-04

2515 Automated acquisition of knowledge beyond pathologists

Yamamoto, Y.; Tsuzuki, T.; Akatsuka, J.; Ueki, M.; Morikawa, H.; Numata, Y.; Takahara, T.; Tsuyuki, T.; Shimizu, A.; Maeda, I.; Tsuchiya, S.; Kanno, H.; Kondo, Y.; Fukumoto, M.; Tamiya, G.; Ueda, N.; Kimura, G.

10.1101/539791 — bioinformatics — Posted on 2019-02-04

2516 GDNF receptor agonist supports dopamine neurons in vitro and protects their function in animal model of Parkinson's disease.

Mahato, A. K.; Renko, J.-M.; Kopra, J.; Visnapuu, T.; Korhonen, I.; Pulkkinen, N.; Bespalov, M. M.; Ronken, E.; Piepponen, T. P.; Voutilainen, M. H.; Tuominen, R. K.; Karelson, M.; Sidorova, Y. A.; Saarma, M.

10.1101/540021 — neuroscience — Posted on 2019-02-04

2517 Relating brain connectivity with persistent symptoms in pediatric concussion

Iyer, K. K.; Barlow, K. M.; Brooks, B.; Ofoghi, Z.; Zalesky, A.; Cocchi, L.

10.1101/539825 — neuroscience — Posted on 2019-02-04

2518 Predicting Empathy from Resting Brain Connectivity

Christov-Moore, L.; Reggente, N.; Douglas, P. K.; Feusner, J.; Iacoboni, M.

10.1101/539551 — neuroscience — Posted on 2019-02-04

2519 Deep-learning based three-dimensional label-free tracking and analysis of immunological synapses of chimeric antigen receptor T cells

Lee, M.; Lee, Y.-H.; Song, J.; Kim, G.; Jo, Y.; Min, H.; Kim, C. H.; Park, Y.

10.1101/539858 — immunology — Posted on 2019-02-04

2520 SLC19A1 is a cyclic dinucleotide transporter

Luteijn, R.; Zaver, S.; Gowen, B. G.; Wyman, S.; Garelis, N.; Onia, L.; McWhirter, S.; Katibah, G.; Corn, J.; Woodward, J.; Raulet, D.

10.1101/539767 — immunology — Posted on 2019-02-04

2521 NMR Mapping of Disordered Segments from a Viral Scaffolding Protein Encapsulated in a 23 MDa Procapsid Complex

Whitehead, R. D.; Teschke, C.; Alexandrescu, A.

10.1101/539965 — biophysics — Posted on 2019-02-04

2522 Bingeing in rats: Persistence of high intakes of palatable solutions induced by 1-in-4-days intermittent access

Rehn, S.; Boakes, R. A.

10.1101/539742 — animal behavior and cognition — Posted on 2019-02-04

2523 Concomitant chemotherapy increases radiotherapy-mediated DNA-damage in peripheral blood lymphocytes

Lorat, Y.; Fleckenstein, J.; Görlinger, P.; Rübe, C.; Rübe, C.

10.1101/540575 — cell biology — Posted on 2019-02-04

2524 Production, purification, and kinetics of the poly-β-hydroxybutyrate depolymerase from Microbacterium paraoxydans RZS6: A novel biopolymer-degrading organism isolated from a dumping yard

Sayyed, R.; SAYYED, R. Z.; Wani, S.; Alyousef, A. A.; Alqasim, A.; Syed, A.

10.1101/540609 — microbiology — Posted on 2019-02-04

2525 DETECTION OF FUSARIUM OXYSPORUM F. SP. ELAEIDIS CAUSING FUSARIUM WILT OF OIL PALM USING LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP)

ADUSEI-FOSU, K.; Dickinson, M.

10.1101/540393 — pathology — Posted on 2019-02-04

2526 Evaluation of DNA extracted from blood filter spots and eluates processed for enzyme linked immunosorbent assay (ELISA)

Offei Owusu, I.; Xatse, M. A.; Akorli, J.; Gati, L.; Wilson, M. D.

10.1101/540633 — molecular biology — Posted on 2019-02-04

2527 Effects of decreased Rac activity and malignant state on oral squamous cell carcinoma

Al-Shareef, H.; Matsuoka, Y.; Kogo, M.; Nakahara, H.

10.1101/540591 — cancer biology — Posted on 2019-02-04

2528 Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

Hosein, A. N.; Huang, H.; Wang, Z.; Parmar, K.; Du, W.; Huang, J.; Maitra, A.; Olson, E.; Verma, U.; Brekken, R. A.

10.1101/539874 — cancer biology — Posted on 2019-02-04

2529 Cyanobacteria is uniquely enriched in the roots of grain amaranths

Srinivasan, S.; Nambisan, S. R.; Choudhary, B.; Sunil, M.

10.1101/540484 — plant biology — Posted on 2019-02-04

2530 Characteristics of executive control network function based on a lateralized version of the ANT-R test in athletes from open skill sports: An fNIRS study

Yu, M.; Liu, Y. b.; Yang, G.; Yuejia Luo, Huanzeng Liu,

10.1101/540500 — physiology — Posted on 2019-02-04

2531 Evolutionary dynamics of de novo mutations and mutant lineages arising in a simple, constant environment

Kinnersley, M.; Schwartz, K.; Boswell, J.; Yang, D.-D.; Sherlock, G.; Rosenzweig, F.

10.1101/540625 — evolutionary biology — Posted on 2019-02-04

2532 Cataract among elderly in Sri Lanka

Nishad, A. A. N.; Hewage, S.; Abeysundara, P. K.; Amaratunge, S.; de Silva, J.; Wickramasinghe, A.; Kasturiratne, K.

10.1101/540518 — epidemiology — Posted on 2019-02-04

2533 Facilitating Replication and Reproducibility in Team Science: the 'projects' R Package

Krieger, N. I.; Perzynski, A. T.; Dalton, J. E.; Northeast Ohio Cohort for Atherosclerotic Risk Estimation (NEOCARE) investigative team,

10.1101/540542 — scientific communication and education — Posted on 2019-02-04

2534 Genome-wide expression analysis identifies core components during iron starvation in hexaploid wheat

Kaur, G.; Shukla, V.; Kumar, A.; Kaur, M.; Goel, P.; Singh, P.; Shukla, A.; Kaur, J.; Singh, J.; Mantri, S.; Rouached, H.; Pandey, A. K.

10.1101/539098 — plant biology — Posted on 2019-02-04

2535 Quantification of alterations in diffusion measures of white matter integrity associated with healthy aging

Molloy, C. J.; Nugent, S.; Bokde, A. L.

10.1101/540443 — neuroscience — Posted on 2019-02-04

2536 Adaptive stress response induced by toluene increases Sporothrix schenckii virulence and host immune response

Tellez-Martinez, D.; Batista-Duharte, A.; Paschoalini Silva, V.; Portuondo Fuentes, D.; Souza Ferreira, L.; Campos Polesi, M.; Barcelos Costa, C.; Zeppone Carlos, I.

10.1101/539775 — microbiology — Posted on 2019-02-04

2537 Complete Chloroplast Genome of Castanopsis sclerophylla (Lindl.) Schott: Genome Structures, Comparative and Phylogenetic Analysis

Ye, X.; Hu, D.; Guo, Y.; Sun, R.

10.1101/540617 — genomics — Posted on 2019-02-04

2538 Optimal sample size calculation for null hypothesis significance tests

Mudge, J.; Houlahan, J.

10.1101/540468 — ecology — Posted on 2019-02-04

2539 Profiling embryonic stem cell differentiation by MALDI-MS: development of a reproducible and robust sample preparation workflow

Heap, R. E.; Segarra Fas, A.; Findlay, G.; Trost, M.

10.1101/536664 — biochemistry — Posted on 2019-02-04

2540 Learning of Spatial Properties of a Large-scale Virtual City with an Interactive Map

König, S. U.; Kakerbeck, V.; Nolte, D.; Duesberg, L.; Kuske, N.; König, P.

10.1101/539080 — neuroscience — Posted on 2019-02-04

2541 Imputation of canine genotype array data using 365 whole-genome sequences improves power of genome-wide association studies

Hayward, J. J.; White, M. E.; Boyle, M.; Shannon, L. M.; Casal, M. L.; Castelhano, M. G.; Center, S. A.; Meyers-Wallen, V. N.; Simpson, K. W.; Sutter, N. B.; Todhunter, R. J.; Boyko, A. R.

10.1101/540559 — genomics — Posted on 2019-02-04

2542 New insights into malaria susceptibility from the genomes of 17,000 individuals from Africa, Asia, and Oceania

Band, G.; Le, Q. S.; Clarke, G. M.; Kivinen, K.; Hubbart, C.; Jeffreys, A. E.; Rowlands, K.; Leffler, E. M.; Jallow, M.; Conway, D. J.; Sisay-Joof, F.; d'Alessandro, U.; Toure, O. B.; Thera, M. A.; Konate, S.; Sissoko, S.; Mangano, V. D.; Bougouma, E. C.; Sirima, S. B.; Amenga-Etego, L. N.; Ghansah, A. K.; Hodgson, A. V. O.; Wilson, M. D.; Enimil, A.; Ansong, D.; Evans, J.; Ademola, S. A.; Apinjoh, T. O.; Ndila, C. M.; Manjurano, A.; Drakeley, C.; Reyburn, H.; Nguyen, H. P.; Nguyen, T. N. Q.; Thai, C. Q.; Hien, T. T.; Teo, Y. Y.; Manning, L.; Laman, M.; Michon, P.; Karunajeewa, H.; Siba, P.;

10.1101/535898 — genetics — Posted on 2019-02-04

2543 Mitochondrial-nuclear heme trafficking is regulated by GTPases that control mitochondrial dynamics.

Martinez-Guzman, O.; Dietz, J. V.; Bohovych, I.; Medlock, A. W.; Khalimonchuk, O.; Reddi, A. R.

10.1101/539254 — cell biology — Posted on 2019-02-04

2544 Hallucinations both in and out of context: An Active Inference Account

Benrimoh, D.; Parr, T.; Adams, R. A.; Friston, K.

10.1101/540419 — neuroscience — Posted on 2019-02-04

2545 Ancient hybridization and introgression of an invadolysin gene in schistosome parasites

Platt, R. N.; McDew-White, M.; Le Clec'h, W.; Chevalier, F. D.; Allan, F.; Emery, A. M.; Garba, A.; Hamidou, A.; Ame, S. M.; Webster, J. P.; Rollinson, D.; Webster, B. L.; Anderson, T. J. C.

10.1101/539353 — evolutionary biology — Posted on 2019-02-04

2546 Streamlining and Cycle Time Reduction of the Start-up Phase of Clinical Trials

Abu-Shaheen, A.; Al Badr, A.; AlFayyad, I.; Al Qutub, A.; Faqeih, E.; Al-Tannir, M.

10.1101/540401 — epidemiology — Posted on 2019-02-04

2547 Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment

Rawlinson, K. A.; Lapraz, F.; Girstmair, J.; Simpson, F.; Criswell, K. E.; Terasaki, M.; Ballister, E. R.; Boldogkoi, M.; McDowell, R. J.; Rodgers, J.; Hall, B. K.; Lucas, R. J.; Telford, M. J.

10.1101/538538 — zoology — Posted on 2019-02-04

2548 Bacterial Glycogen as a Durable Energy Reserve Contributing to Persistence: An Updated Bibliography and Mathematical Model

Wang, L.; Liu, Q.; Tan, X.; Yang, T.; Tang, D.; Wang, W.; Wise, M.

10.1101/536110 — microbiology — Posted on 2019-02-04

2549 Internalization of erythrocyte acylpeptide hydrolase is required for asexual replication of Plasmodium falciparum

Elahi, R.; Dapper, C.; Klemba, M.

10.1101/533570 — microbiology — Posted on 2019-02-04

2550 Dual role of protease activated receptor 4 in acute kidney injury: contributing to renal injury and inflammation, while maintaining the renal filtration barrier upon acute renal ischemia reperfusion injury

Jansen, M.; Claessen, N.; Larsen, P. W. B.; Butter, L.; Florquin, S.; Roelofs, J. J. T. H.

10.1101/540427 — immunology — Posted on 2019-02-04

2551 Hypothesis-testing Improves the Predicted Reliability of Neuroscience Research

Alger, B. E.

10.1101/537365 — neuroscience — Posted on 2019-02-04

2552 Experience-related alterations in white matter structure and gene expression in adult rats

Sampaio-Baptista, C.; Valles, A.; Khrapitchev, A. A.; Akkermans, G.; Winkler, A.; Foxley, S.; Sibson, N. R.; Roberts, M.; Miller, K.; Diamond, M. E.; Martens, G. J. M.; De Weerd, P.; Johansen-Berg, H.

10.1101/532572 — neuroscience — Posted on 2019-02-04

2553 Evolution of the nonsense-mediated decay (NMD) pathway is associated with decreased cytolytic immune infiltration

Pritchard, J. R.; Zhao, B.

10.1101/535773 — cancer biology — Posted on 2019-02-04

2554 HABIT - a webserver for interactive T cell neoepitope discovery

Martins, J.; Magalhaes, C.; Vieira, V.; Rocha, M.; Osorio, N. S.

10.1101/535716 — bioinformatics — Posted on 2019-02-04

2555 KAI2 regulates root and root hair development by modulating auxin distribution

Villaecija Aguilar, J. A.; Hamon-Josse, M.; Carbonnel, S.; Kretschmar, A.; Ljung, K.; Bennett, T.; Gutjahr, C.

10.1101/539734 — plant biology — Posted on 2019-02-03

2556 Can transcranial direct current stimulation over the dorsolateral prefrontal cortex enhance proprioception?

Beck, E. N.; Shankar Narayanan, S.; McDermott, R.; Witney, A.

10.1101/539510 — neuroscience — Posted on 2019-02-03

2557 Toll-like receptor 2 stimulation augments esophageal epithelial barrier integrity

Ruffner, M. A.; Song, L.; Mauerer, K.; Shi, L.; Carroll, M. C.; Wang, J. X.; Muir, A. B.; Spergel, J. M.; Sullivan, K. E.

10.1101/539759 — immunology — Posted on 2019-02-03

2558 Mechanism of electroneutral sodium/proton antiporter from transition-path shooting

Okazaki, K.-i.; Woehlert, D.; Warnau, J.; Jung, H.; Yildiz, O.; Kuehlbrandt, W.; Hummer, G.

10.1101/538777 — biophysics — Posted on 2019-02-03

2559 Multiomic definition of generalizable endotypes in human acute pancreatitis.

Neyton, L.; Zheng, X.; Skouras, C.; Wilson, A. B.; Gutmann, M. U.; Yau, C.; Uings, I. J.; Rao, F. V.; Nicolas, A.; Marshall, C.; Wilson, L.-M.; Baillie, J. K.; Mole, D. J.

10.1101/539569 — systems biology — Posted on 2019-02-03

2560 Quantifying bacterial fitness in intracellular dynamics

Pauperio, F. F. S.; Gjini, E.

10.1101/539163 — systems biology — Posted on 2019-02-03

2561 Cerebral Metabolic Changes during Visuomotor Adaptation Assessed using Quantitative FMRI

Foster, C.; Steventon, J.; Helme, D.; Tomassini, V.; Wise, R. G.

10.1101/539130 — neuroscience — Posted on 2019-02-03

2562 Assessment of the effects of aerobic fitness on cerebrovascular function in young adults using multiple inversion time arterial spin labelling MRI

Foster, C.; Steventon, J.; Helme, D.; Tomassini, V.; Wise, R. G.

10.1101/539072 — neuroscience — Posted on 2019-02-03

2563 DONOR-FREE GENE CORRECTION BY TARGETED INTERHOMOLOG RECOMBINATION

Davis, L.; Khoo, K. J.; Maizels, N.

10.1101/538603 — genetics — Posted on 2019-02-03

2564 A DACT1 enhancer modulates brain asymmetric temporal regions involved in language processing

Le Guen, Y.; Leroy, F.; Philippe, C.; IMAGEN Consortium, ; Mangin, J.-F.; Dehaene-Lambertz, G.; Frouin, V.

10.1101/539189 — neuroscience — Posted on 2019-02-03

2565 Hearing loss promotes schizophrenia-relevant brain and behavioral abnormalities in a mouse model of human 22q11.2 Deletion Syndrome

Zinnamon, F. A.; Harrison, F. G.; Wenas, S. S.; Meyer, A. F.; Liu, Q.; Wang, K. H.; Linden, J. F.

10.1101/539650 — neuroscience — Posted on 2019-02-03

2566 Translating antibiotic prescribing into antimicrobial resistance in the environment: a hazard characterisation case study

Singer, A. C.; Xu, Q.; Keller, V. D.

10.1101/539536 — microbiology — Posted on 2019-02-03

2567 Divergence-based introgression polarization

Forsythe, E. S.; Sloan, D. B.; Beilstein, M. A.

10.1101/539197 — evolutionary biology — Posted on 2019-02-03

2568 Semantic coding in the occipital cortex of early blind individuals

Abboud, S.; Engemann, D.-A.; Cohen, L.

10.1101/539437 — neuroscience — Posted on 2019-02-03

2569 Both the inflammatory response and clinical outcome differ markedly between adults with pneumococcal and meningococcal meningitis in a high HIV-1 prevalent setting in sub-Saharan Africa

Wall, E. C.; Guerra-Assuncao, J. A.; Denis, B.; Scarborough, M.; Ajdukiewicz, K.; Cartwright, K.; Mukaka, M.; Mlozowa, V. S.; Venturini, C.; Allain, T. J.; Lalloo, D. G.; Brown, J. S.; Gordon, S. B.; Heyderman, R. S.

10.1101/539585 — immunology — Posted on 2019-02-03

2570 Scalable and Accurate Drug-target Prediction Based on Heterogeneous Bio-linked Network Mining

Zong, N.; Wong, R. S. N.; Ngo, V.; Yu, Y.; Li, N.

10.1101/539643 — bioinformatics — Posted on 2019-02-03

2571 Androgens enhance adult hippocampal neurogenesis in males but not females in an age-dependent manner

Duarte-Guterman, P.; Hamson, D.; Wainwright, S.; Chow, C.; Chaiton, J.; Lieblich, S. E.; Watson, N. V.; Galea, L. A.

10.1101/539296 — neuroscience — Posted on 2019-02-03

2572 Deep motif deconvolution of HLA-II peptidomes for robust class II epitope predictions

Racle, J.; Michaux, J.; Rockinger, G. A.; Arnaud, M.; Bobisse, S.; Chong, C.; Guillaume, P.; Coukos, G.; Harari, A.; Jandus, C.; Bassani-Sternberg, M.; Gfeller, D.

10.1101/539338 — immunology — Posted on 2019-02-03

2573 A Novel Neoantigen Discovery Approach based on Chromatin High Order Conformation: Mapping the Neoantigen to 3D Genome

Shang, X.; Zhang, M.; Meng, L.; Su, X.; Li, Q.; Lin, M.; Zou, X.; Luo, Q.; Zhai, Y.; He, K.; Wang, L.; Da, L.; Cai, W. T.; Han, Z.-g.; Shi, Y.

10.1101/539387 — bioinformatics — Posted on 2019-02-03

2574 Protein thermal stability engineering using HoTMuSiC

Pucci, F.; Kwasigroch, J. M.; Rooman, M.

10.1101/539528 — bioinformatics — Posted on 2019-02-03

2575 Locus-coeruleus norepinephrine activity gates sensory-evoked awakenings from sleep

Hayat, H.; Regev, N.; Matosevich, N.; Sales, A.; Paredes-Rodriguez, E.; Krom, A. J.; Bergman, L.; Li, Y.; Lavigne, M.; Kremer, E. J.; Yizhar, O.; Pickering, A. E.; Nir, Y.

10.1101/539502 — neuroscience — Posted on 2019-02-03

2576 Transfer learning of deep neural network representations for fMRI decoding

Svanera, M.; Savardi, M.; Benini, S.; Signoroni, A.; Raz, G.; Hendler, T.; Muckli, L.; Goebel, R.; Valente, G.

10.1101/535377 — neuroscience — Posted on 2019-02-03

2577 Systematic mapping of drug metabolism by the human gut microbiome

Chankhamjon, P.; Javdan, B.; Lopez, J.; Hull, R.; Chatterjee, S.; Donia, M. S.

10.1101/538215 — microbiology — Posted on 2019-02-03

2578 Hybrid genome assembly and annotation of Danionella translucida, a transparent fish with the smallest known vertebrate brain

Kadobianskyi, M.; Schulze, L.; Schuelke, M.; Judkewitz, B.

10.1101/539692 — genomics — Posted on 2019-02-03

2579 Investigating the Association Between Body Fat and Depression via Mendelian Randomization

Speed, M.; Jefsen, O.; Boerglum, A.; Speed, D.; Oestergaard, S. D.

10.1101/539601 — genetics — Posted on 2019-02-03

2580 Decomposing Mutation and Selection to Identify Mismatched Codon Usage

Landerer, C.; O'Meara, B. C.; Zaretzki, R.; Gilchrist, M. A.

10.1101/539148 — evolutionary biology — Posted on 2019-02-03

2581 METASPACE: A community-populated knowledge base of spatial metabolomes in health and disease

Alexandrov, T.; Ovchnnikova, K.; Palmer, A.; Kovalev, V.; Tarasov, A.; Stuart, L.; Nigmetzianov, R.; Fay, D.; Key METASPACE Contributors,

10.1101/539478 — systems biology — Posted on 2019-02-03

2582 Cerebral Ischemic-Hypoxia Induces TRPC6 in the Glomerular Podocytes: A Novel Role for HIF1α-ZEB2 Axis in the Pathogenesis of Stroke-induced Proteinuria

Nakuluri, K.; Nishad, R.; Mukhi, D.; Teertam, S. K.; Nakka, V. P.; Narne, P.; Natuva, S. S. K.; Phanithi, P. B.; Pasupulati, A. K.

10.1101/538959 — pathology — Posted on 2019-02-03

2583 Modeling of fibrotic lung disease using 3D organoids derived from human pluripotent stem cells

Snoeck, H.-W.; Strikoudis, A.; Loffredo, L.; Chen, Y.-W.

10.1101/538991 — pathology — Posted on 2019-02-03

2584 A new comprehensive Eye-Tracking Test Battery concurrently evaluating the Pupil Labs Glasses and the EyeLink 1000

Ehinger, B. V.; Gross, K.; Ibs, I.; Koenig, P.

10.1101/536243 — neuroscience — Posted on 2019-02-03

2585 Visual closed-loop dynamics via ocular drift

Gruber, L. Z.; Ahissar, E.

10.1101/539445 — neuroscience — Posted on 2019-02-03

2586 Memory-guided microsaccades

Willeke, K.-F.; Tian, X.; Buonocore, A.; Bellet, J.; Ramirez-Cardenas, A.; Hafed, Z.

10.1101/539205 — neuroscience — Posted on 2019-02-03

2587 Global phylogenomics of multidrug resistant Salmonella enterica serotype Kentucky ST198

Hawkey, J.; Le Hello, S.; Doublet, B.; Granier, S.; Hendriksen, R.; Fricke, W. F.; Ceyssens, P.-J.; Gomart, C.; Billman-Jacobe, H.; Holt, K. E.; Weill, F.-X.

10.1101/535914 — microbiology — Posted on 2019-02-03

2588 Identification of novel mobilized colistin resistance gene mcr-9 in a multidrug-resistant, colistin-susceptible Salmonella enterica serotype Typhimurium isolate using a combination of high-throughput, in silico screening and functional analysis

Carroll, L. M.; Gaballa, A.; Guldimann, C.; Sullivan, G.; Henderson, L. O.; Wiedmann, M.

10.1101/539361 — microbiology — Posted on 2019-02-03

2589 Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila

Pherson, M.; Misulovin, Z.; Gause, M.; Dorsett, D.

10.1101/539270 — genomics — Posted on 2019-02-03

2590 Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

Hsiao, C. J.; Tung, P.; Blischak, J. D.; Burnett, J.; Barr, K.; Dey, K. K.; Stephens, M.; Gilad, Y.

10.1101/526848 — genomics — Posted on 2019-02-03

2591 Analysis of the recombination landscape of hexaploid bread wheat reveals genes controlling recombination and gene conversion frequency

Gardiner, L.-J.; Wingen, L. U.; Bailey, P.; Joynson, R.; Brabbs, T.; Wright, J.; Higgins, J. D.; Hall, N.; Griffiths, S.; Clavijo, B. J.; Hall, A.

10.1101/539684 — genetics — Posted on 2019-02-03

2592 Episodic diversifying selection and intragenomic interactions shape the evolution of DNA and RNA viruses

Aris-Brosou, S.; Parent, L.; Ibeh, N.

10.1101/539239 — evolutionary biology — Posted on 2019-02-03

2593 Functional traits and phenotypic plasticity modulate species coexistence across contrasting environments

Perez-Ramos, I. M.; Matias, L.; Gomez Aparicio, L.; Godoy, O.

10.1101/539619 — ecology — Posted on 2019-02-03

2594 LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1

Patel, D.; Ahmad, F.; Kambach, D. M.; Sun, Q.; Halim, A. S.; Stommel, J. M.

10.1101/539221 — cancer biology — Posted on 2019-02-03

2595 SUBSTRA: Supervised Bayesian Patient Stratification

Khakabimamaghani, S.; Kelkar, Y.; Grande, B.; Morin, R.; Ester, M.; Ziemek, D.

10.1101/538512 — bioinformatics — Posted on 2019-02-03

2596 A Genome-Wide Association Study of Non-Photochemical Quenching in response to local seasonal climates in Arabidopsis thaliana

Rungrat, T.; Almonte, A. A.; Cheng, R.; Gollan, P. J.; Stuart, T.; Aro, E.-M.; Borevitz, J. O.; Pogson, B.; Wilson, P. B.

10.1101/539379 — plant biology — Posted on 2019-02-03

2597 Reduced Plasma Ascorbic Acid Levels in Recipients of Myeloablative Conditioning & Hematopoietic Cell Transplantation

Rasheed, M.; Simmons, G.; Fisher, B.; Leslie, K.; Reed, J.; Roberts, C.; Natarajan, R.; Fowler, A.; Toor, A.

10.1101/539007 — physiology — Posted on 2019-02-03

2598 Ecological origins of perceptual grouping principles in the auditory system

Mlynarski, W.; McDermott, J. H.

10.1101/539635 — neuroscience — Posted on 2019-02-03

2599 Competition and immune selection of multi-strain Plasmodium falciparum malaria

Gurarie, D.

10.1101/539676 — evolutionary biology — Posted on 2019-02-03

2600 Generalization as diffusion: human function learning on graphs

Wu, C. M.; Schulz, E.; Gershman, S. J.

10.1101/538934 — animal behavior and cognition — Posted on 2019-02-03

2601 A new mechanism for tree mortality due to drought and heatwaves

Cochard, H.

10.1101/531632 — plant biology — Posted on 2019-02-03

2602 HtrA1 alters endothelial tube formation characteristics in an in vitro model

Singh, H.; Nie, G.

10.1101/539304 — cell biology — Posted on 2019-02-03

2603 Molecular dissection of the cellular response to mechanical stress

Zuela - Sopilniak, N.; Dorfman, J.; Gruenbaum, Y.

10.1101/539262 — genetics — Posted on 2019-02-03

2604 2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Carozza, J. A.; Boehnert, V.; Shaw, K. E.; Nguyen, K. C.; Skariah, G.; Brown, J. A.; Rafat, M.; von Eyben, R.; Graves, E. E.; Glenn, J. S.; Smith, M.; Li, L.

10.1101/539312 — biochemistry — Posted on 2019-02-03

2605 Computational identification of novel Kir6 channel inhibitors

Chen, X.; Garon, A.; Wieder, M.; Houtman, M. J. C.; Zangerl-Plessl, E.-M.; Langer, T.; van der Heyden, M. A. G.; Stary-Weinzinger, A.

10.1101/539460 — pharmacology and toxicology — Posted on 2019-02-03

2606 Spatial resets modulate YAP-dependent transcription

Franklin, J. M.; Ghosh, R. P.; Shi, Q.; Liphardt, J. T.

10.1101/539049 — cell biology — Posted on 2019-02-03

2607 Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model

Adler, P.; Mayne, J.; Walker, K.; Ning, Z.; Figeys, D.

10.1101/539627 — biochemistry — Posted on 2019-02-03

2608 Deep Brain Stimulation of the Ventromedial Prefrontal Cortex Disrupts Consolidation of Fear Memories

Tan, S. Z. K.; Poon, C. H.; Chan, Y.-S.; Lim, L. W.

10.1101/537514 — neuroscience — Posted on 2019-02-03

2609 MAUI-seq: Multiplexed, high-throughput amplicon diversity profiling using unique molecular identifiers

Fields, B.; Moeskjaer, S.; Friman, V.-P.; Andersen, S. U.; Young, J. P. W.

10.1101/538587 — ecology — Posted on 2019-02-03

2610 SLC19A1 is an importer of the immunotransmitter cGAMP

Cordova, A. F.; Ritchie, C.; Hess, G. T.; Bassik, M. C.; Li, L.

10.1101/539247 — biochemistry — Posted on 2019-02-03

2611 Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma

Huang, H. H.-L.; Ferguson, I. D.; Thornton, A. M.; Lam, C. Y. T.; Lin, Y.-H. T.; Bastola, P.; Choudhry, P.; Mariano, M. C.; Marcoulis, M. D.; Malato, J.; Phojanakong, P.; Martin, T. G.; Wolf, J. L.; Wong, S. W.; Shah, N.; Hann, B. C.; Brooks, A. N.; Wiita, A. P.

10.1101/508549 — cancer biology — Posted on 2019-02-03

2612 Modeling enamel matrix secretion in mammalian teeth

Hakkinen, T. J.; Sova, S. S.; Corfe, I. J.; Tjaderhane, L.; Hannukainen, A.; Jernvall, J.

10.1101/525162 — biophysics — Posted on 2019-02-03

2613 SPR-measured dissociation kinetics of PROTAC ternary complexes influence target degradation rate

Roy, M. J.; Winkler, S.; Hughes, S. J.; Whitworth, C.; Galant, M.; Farnaby, W.; Rumpel, K.; Ciulli, A.

10.1101/451948 — biochemistry — Posted on 2019-02-03

2614 Computational analysis of molecular networks using spectral graph theory, complexity measures and information theory

Huang, C.-H.; Tsai, J. J. P.; Kurubanjerdjit, N.; Ng, K.-L.

10.1101/536318 — systems biology — Posted on 2019-02-02

2615 Alzheimer's disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation

Petersen, C.; Nolan, A. L.; de Paula Franca Resende, E.; Ehrenberg, A. J.; Spina, S.; Miller, B. L.; Seeley, W.; Miller, Z.; Grinberg, L.

10.1101/538496 — pathology — Posted on 2019-02-02

2616 Dissociable Cerebellar-Prefrontal Networks Underlying Executive Function: Evidence from the Human Connectome Project

Orr, J. M.; Jackson, T. B.; Imburgio, M. J.; Bernard, J. A.

10.1101/431593 — neuroscience — Posted on 2019-02-02

2617 Robust estimation of sulcal morphology

Madan, C. R.

10.1101/452789 — neuroscience — Posted on 2019-02-02

2618 Perturbations of a Kinase-Pseudokinase Module Activate Plant Immunity

Bastedo, D. P.; Seto, D.; Martel, A.; Khan, M.; Kireeva, I.; Zhang, J.; Masud, W.; Millar, D.; Lee, J. Y.; Lee, A. H.-Y.; Gong, Y.; Santos-Severino, A.; Guttman, D. S.; Desveaux, D.

10.1101/531665 — molecular biology — Posted on 2019-02-02

2619 Hemocyte subpopulation changes in Bithynia snails infected with Opisthorchis viverrini in Thailand.

Suwannatrai, K.; Thinkhamrop Suwannatrai, A.; Donthaisong, C.; Arunsan, P.; Thinkhamrop, K.; Tabsripair, P.; Welbat, J. U.; Tangkawattana, S.; Sotillo, J.; Tesana, S.

10.1101/536292 — immunology — Posted on 2019-02-02

2620 The fitness cost of a congenital heart defect shapes its genetic architecture

Akhirome, E. O.; Regmi, S. D.; Magnan, R.; Ugwu, N.; Qin, Y.; Schulkey, C. E.; Cheverud, J. M.; Jay, P. Y.

10.1101/531988 — genetics — Posted on 2019-02-02

2621 Osteocyte death and bone overgrowth in mice lacking Fibroblast Growth Factor Receptors 1 and 2 in mature osteoblasts and osteocytes

McKenzie, J.; Smith, C.; Karuppaiah, K.; Langberg, J.; Silva, M. J.; Ornitz, D. M.

10.1101/474502 — developmental biology — Posted on 2019-02-02

2622 Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes

Navarro-Serer, B.; Childers, E. P.; Hermance, N. M.; Mercadante, D.; Manning, A. L.

10.1101/401661 — cancer biology — Posted on 2019-02-02

2623 Hydrogen Bond Donors and Acceptors are Generally Depolarized in α-Helices as Revealed by a Molecular Tailoring Approach

Kondo, H. X.; Kusaka, A.; Kitakawa, C. K.; Onari, J.; Yamanaka, S.; Nakamura, H.; Takano, Y.

10.1101/536755 — biophysics — Posted on 2019-02-02

2624 Internal noise in contrast discrimination propagates forwards from early visual cortex

Vilidaite, G.; Marsh, E.; Baker, D.

10.1101/364612 — neuroscience — Posted on 2019-02-02

2625 Bacterial swarming reduces Proteus mirabilis and Vibrio parahaemolyticus cell stiffness and increases β-lactam susceptibility

Auer, G. K.; Oliver, P. M.; Rajendram, M.; Lin, T.-Y.; Yao, Q.; Jensen, G. J.; Weibel, D. B.

10.1101/275941 — microbiology — Posted on 2019-02-02

2626 Brain-derived circulating cell-free DNA defines the brain region and cell specific origins associated with neuronal atrophy

Chatterton, Z.; Mendelev, N.; Chen, S.; Raj, T.; Walker, R.; Carr, W.; Kamimori, G.; Beeri, M.; Ge, Y.; Dwork, A.; Haghighi, F.

10.1101/538827 — genomics — Posted on 2019-02-02

2627 The conserved histone chaperone LIN-53 links lifespan and healthspan regulation in C. elegans

Muethel, S.; Uyar, B.; He, M.; Krause, A.; Vitrinel, B.; Bulut, S.; Vasiljevic, D.; Akalin, A.; Kempa, S.; Tursun, B.

10.1101/539015 — cell biology — Posted on 2019-02-02

2628 Differential gene expression and the importance of regulatory ncRNAs in acidophilic microorganisms

Aliaga Goltsman, D. S.; Hauser, L.; Dasari, M.; Thomas, B. C.; BANFIELD, J. F.

10.1101/538918 — microbiology — Posted on 2019-02-02

2629 Necessary Conditions for Reliable Representation of Asynchronous Spikes Through a Single-layered Feedforward Network

Lankarany, M.

10.1101/538736 — neuroscience — Posted on 2019-02-02

2630 Transketolase is involved in the control of Sigma B during chronic infection by Staphylococcus aureus

Tan, X.; Ramond, E.; jamet, a.; Decaux-Tramoni, B.; Dupuis, M.; euphrasie, d.; Tros, F.; Nemazanyy, I.; Ziveri, J.; Nassif, X.; Charbit, A.; Coureuil, M.

10.1101/538900 — microbiology — Posted on 2019-02-02

2631 DNA Nanostructures Coordinate Gene Silencing in Mature Plants

Zhang, H.; Demirer, G. S.; Zhang, H.; Ye, T.; Goh, N. S.; Aditham, A. J.; Cunningham, F. J.; Fan, C.; Landry, M.

10.1101/538678 — plant biology — Posted on 2019-02-02

2632 DNA methylation and histone H1 cooperatively repress transposable elements and aberrant intragenic transcripts

Choi, J.; Lyons, D. B.; Kim, Y.; Moore, J. D.; Zilberman, D.

10.1101/527523 — genetics — Posted on 2019-02-02

2633 SynQuant: An Automatic Tool to Quantify Synapses from Microscopy Images

Wang, Y.; Wang, C.; Ranefall, P.; Broussard, G.; Wang, Y.; Shi, G.; Wang, Y.; Tian, L.; Yu, G.

10.1101/538769 — neuroscience — Posted on 2019-02-02

2634 Dynamics in coastal RNA viruses and bacteriophages are driven by shifts in the community phylogenetic structure

Gustavsen, J. A.; Suttle, C.

10.1101/538892 — microbiology — Posted on 2019-02-02

2635 SHIV.CH505-infected infant and adult rhesus macaques exhibit similar HIV Env-specific antibody kinetics, despite distinct T-follicular helper (Tfh) and germinal center B cell landscapes

Nelson, A. N.; Goswami, R.; Dennis, M.; Tu, J.; Mangan, R.; Saha, P. T.; Cain, D. W.; Shen, X.; Shaw, G. M.; Bar, K. J.; Hudgens, M. G.; Pollara, J.; De Paris, K.; Van Rompay, K. K. A.; Permar, S. R.

10.1101/538876 — immunology — Posted on 2019-02-02

2636 Differences in Long-Chained Cuticular Hydrocarbons between Males and Gynes in Cataglyphis Desert Ants

Inbar, S.; Privman, E.

10.1101/538926 — ecology — Posted on 2019-02-02

2637 C. elegans synMuv B proteins regulate spatial and temporal chromatin compaction during development

Costello, M. E.; Petrella, L.

10.1101/538801 — developmental biology — Posted on 2019-02-02

2638 First Crystal Structure of a Non-Structural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein

Proudfoot, A.; Hyrina, A.; Holdorf, M.; Frank, A.; Bussiere, D.

10.1101/538884 — biophysics — Posted on 2019-02-02

2639 Unveiling the transcriptome complexity of the High- and Low- Zinc & Iron accumulating Indian wheat (Triticum aestivum L.) cultivars

Mishra, V. K.; Gupta, S.; Chand, R.; Yadav, P. S.; Singh, S. K.; Joshi, A. K.; Varadwaj, P. K.

10.1101/538819 — bioinformatics — Posted on 2019-02-02

2640 OsCYP71D8L as a key regulator involved in growth and stress response by mediating gibberellins and cytokinins homeostasis in rice

Zhou, J.; Li, Z.; Xiao, G.; Huang, R.; Zhang, H.

10.1101/538785 — plant biology — Posted on 2019-02-02

2641 Potential role of extracellular ATP released by bacteria in bladder infection and contractility

Burton, J. P.; Abbasian, B.; Shair, A.; O'Gorman, D. B.; Pena-Diaz, A. M.; Engelbrecht, K. C.; Koenig, D. W.; Reid, G.

10.1101/538868 — microbiology — Posted on 2019-02-02

2642 Quantitative analysis of the ThrbCRM1-centered gene regulatory network

Souferi, B.; Emerson, M.

10.1101/538751 — developmental biology — Posted on 2019-02-02

2643 Formal axioms in biomedical ontologies improve analysis and interpretation of associated data

Smaili, F. Z.; Gao, X.; Hoehndorf, R.

10.1101/536649 — bioinformatics — Posted on 2019-02-02

2644 SuperCRUNCH: A toolkit for creating and manipulating supermatrices and other large phylogenetic datasets

Portik, D.; Wiens, J.

10.1101/538728 — bioinformatics — Posted on 2019-02-02

2645 Computational analysis of molecular networks using spectral graph theory, complexity measures and information theory

Huang, C.-H.; Tsai, J. J. P.; Kurubanjerdjit, N.; Ng, K.-L.

10.1101/536318 — systems biology — Posted on 2019-02-02

2646 Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei

Chewapreecha, C.; Mather, A. E.; Harris, S. R.; Hunt, M.; Holden, M.; Chaichana, C.; Wuthiekanun, V.; Dougan, G.; Day, N.; Limmathurotsakul, D.; Pakhill, J.; Peacock, S.

10.1101/538793 — microbiology — Posted on 2019-02-02

2647 Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine improves insulin sensitivity and reduces atherosclerosis through modulating inflammatory Ly6Chi monocytosis and macrophage polarization

Huang, J.; Yancey, P. G.; May-Zhang, L.; Tao, H.; Zhang, Y.; Ding, L.; Oates, J. A.; Amarnath, V.; Roberts, J. L.; Davies, S. S.; Linton, M. F.

10.1101/529339 — pharmacology and toxicology — Posted on 2019-02-02

2648 Identification of genes with enriched expression in early developing mouse cone photoreceptors

Buenaventura, D. F.; Corseri, A.; Emerson, M. M.

10.1101/538611 — developmental biology — Posted on 2019-02-02

2649 Resilient Living Materials Built By Printing Bacterial Spores

Gonzalez, L. M.; Voigt, C. A.

10.1101/537571 — bioengineering — Posted on 2019-02-02

2650 Treatment with 5-aza-dC Induces Apoptotic PARP1-DNA Adducts

Kiianitsa, K.; Zhang, Y.; Maizels, N.

10.1101/538645 — biochemistry — Posted on 2019-02-02

2651 Single cell profiling of CRISPR/Cas9-induced OTX2 deficient retinas reveals fate switch from restricted progenitors

Ghinia Tegla, M. G.; Buenaventura, D. F.; Kim, D. Y.; Thakurdin, C.; Gonzalez, K. C.; Emerson, M. M.

10.1101/538710 — developmental biology — Posted on 2019-02-02

2652 Perceptions and Prospects in Life Sciences in a Heterogeneous Latin American Population

Ferreira, L. M. R.; Carosso, G. A.; Lopez-Videla, B.; Vaca Diez, G.; Rivera-Betancourt, L. I.; Rodriguez, Y.; Ordonez, D. G.; Montellano Duran, N.; Alatriste-Gonzalez, D. K.; Vacaflores, A.; Bohorquez, S.; Gonzalez Auza, L.; Schuetz, C.; Alexander-Savino, C.; Gandarilla Cuellar, O.; Mostajo Radji, M. A.

10.1101/514216 — scientific communication and education — Posted on 2019-02-02

2653 Ramping and phasic dopamine activity accounts for efficient cognitive resource allocation during reinforcement learning.

Song, M. R.; Lee, S. W.

10.1101/381103 — neuroscience — Posted on 2019-02-02

2654 TMS-evoked EEG potentials from prefrontal and parietal cortex: reliability, site specificity, and effects of NMDA receptor blockade

Rogasch, N.; Zipser, C.; Darmani, G.; Mutanen, T. P.; Biabani, M.; Zrenner, C.; Desideri, D.; Belardinelli, P.; Müller-Dahlhaus, F.; Ziemann, U.

10.1101/480111 — neuroscience — Posted on 2019-02-02

2655 Pleiotropic effects of ebony and tan on pigmentation and cuticular hydrocarbon composition in Drosophila melanogaster

Massey, J. H.; Akiyama, N.; Bien, T.; Dreisewerd, K.; Wittkopp, P. J.; Yew, J. Y.; Takahashi, A.

10.1101/538090 — genetics — Posted on 2019-02-01

2656 Reconstructing and Analysing The Genome of The Last Eukaryote Common Ancestor to Better Understand the Transition from FECA to LECA.

Newman, D.; Whelan, F.; Moore, M.; Rusilowicz, M.; McInerney, J. O.

10.1101/538264 — evolutionary biology — Posted on 2019-02-01

2657 Modeling microbial communities using biochemical resource allocation analysis

Sharma, S.; Steuer, R.

10.1101/537779 — systems biology — Posted on 2019-02-01

2658 A curated transcriptome dataset collection to investigate inborn errors of immunity.

Bougarn, S.; Boughorbel, S.; Chaussabel, D.; Marr, N.

10.1101/526004 — immunology — Posted on 2019-02-01

2659 A practive faeces collection protocol for multidisciplinary research in wildlife science

Biswas, S.; Bhatt, S.; Paul, S.; Modi, S.; Ghosh, T.; Habib, B.; Nigam, P.; Talukdar, G.; Pandav, B.; Mondol, S.

10.1101/537803 — ecology — Posted on 2019-02-01

2660 Development of Triazoles based on AZT and their Anti-Viral Activity Against HIV-1

Alencar, D.; Goncalves, J.; A. Cerqueira, S.; Soares, H.; Petronilho, A.

10.1101/523225 — biochemistry — Posted on 2019-02-01

2661 Effect of flow rate and freezing on cyanocobalamin recovery using a commercial solid phase extraction cartridge.

Lees, L.; Bland, A.; DiTullio, G.; Janech, M. G.; Lee, P. A.

10.1101/538355 — biochemistry — Posted on 2019-02-01

2662 Screening for neurotoxic potential of 15 flame retardants using freshwater planarians

Zhang, S.; Ireland, D.; Sipes, N. S.; Behl, M.; Collins, E.-M. S.

10.1101/538280 — pharmacology and toxicology — Posted on 2019-02-01

2663 Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus

Bezar, I. F.; Mashruwala, A. A.; Boyd, J. M.; Stock, A. M.

10.1101/538173 — microbiology — Posted on 2019-02-01

2664 The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders

Miller-Rhodes, P.; Kong, C.; Baht, G. S.; Rodriguiz, R. M.; Wetsel, W. C.; Gelbard, H. A.; Terrando, N.

10.1101/537472 — neuroscience — Posted on 2019-02-01

2665 Extracellular spike waveform dissociates four functionally distinct cell classes in primate cortex

Trainito, C.; von Nicolai, C.; Miller, E. K.; Siegel, M.

10.1101/537738 — neuroscience — Posted on 2019-02-01

2666 Hif-1α stabilisation polarises macrophages via cyclooxygenase/prostaglandin E2 in vivo

Lewis, A.; Elks, P. M.

10.1101/536862 — immunology — Posted on 2019-02-01

2667 Mito-SinCe2 Approach to Quantify Relationships between Mitochondrial Dynamics and Energetics status

Mitra, K.; Spurlock, B.; Gupta, P.; Basu, M. K.; Mukherjee, A.; Hjelmeland, A.; Darley-Usmar, V.; Parker, D.; Foxall, M.

10.1101/537373 — cell biology — Posted on 2019-02-01

2668 GeNet: Deep Representations for Metagenomics

Rojas-Carulla, M.; Tolstikhin, I.; Luque, G.; Youngblut, N.; Ley, R.; Schoelkopf, B.

10.1101/537795 — bioinformatics — Posted on 2019-02-01

2669 Structural and binding studies of human CAMKK2 kinase domain bound to small molecule ligands

Profeta, G. S.; dos Reis, C. V.; Godoi, P. H.; Fala, A. M.; Satori, R.; Salmazo, A. P.; Ramos, P. Z.; Massirer, K. B.; Elkins, J. M.; Drewry, D. H.; Gileadi, O.; Counago, R. M.

10.1101/538157 — biochemistry — Posted on 2019-02-01

2670 Obesity alters mobility and adult neurogenesis, but not hippocampal dependent learning in ob/ob mice

Bracke, A.; Domanska, G.; Bracke, K.; Harzsch, S.; van den Brandt, J.; Broeker, B.; von Bohlen und Halbach, O.

10.1101/537720 — neuroscience — Posted on 2019-02-01

2671 Causes and consequences of cellulose production by Pseudomonas fluorescens SBW25 at the air-liquid interface

Ardre, M.; Rainey, P. B.

10.1101/538561 — microbiology — Posted on 2019-02-01

2672 Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance in a model gut microbiota

Aranda-Diaz, A.; Obadia, B.; Thomsen, T.; Hallberg, Z. F.; Guvener, Z. T.; Huang, K. C.; Ludington, W. B.

10.1101/538132 — microbiology — Posted on 2019-02-01

2673 Modelling plastics exposure for the marine biota: Risk maps for fin whales in the Pelagos Sanctuary (North-Western Mediterranean)

Guerrini, F.; Mari, L.; Casagrandi, R.

10.1101/538058 — ecology — Posted on 2019-02-01

2674 Continuous, Topologically Guided Protein Crystallization Controls Bacterial Surface Layer Self-Assembly

Comerci, C. J.; Herrmann, J.; Yoon, J.; Jabbarpour, F.; Zhou, X.; Nomellini, J. F.; Smit, J.; Shapiro, L.; Wakatsuki, S.; Moerner, W. E.

10.1101/538397 — biophysics — Posted on 2019-02-01

2675 Assessing graph-based read mappers against a novel baseline approach highlights strengths and weaknesses of the current generation of methods

Grytten, I.; Rand, K. D.; Nederbragt, A. J.; Sandve, G. K.

10.1101/538066 — bioinformatics — Posted on 2019-02-01

2676 Millefy: visualizing cell-to-cell heterogeneity in read coverage of single-cell RNA sequencing datasets

Ozaki, H.; Hayashi, T.; Mana, U.; Nikaido, I.

10.1101/537936 — bioinformatics — Posted on 2019-02-01

2677 A Stomata Classification and Detection System in Microscope Images of Maize Cultivars

Aono, A.; Nagai, J.; Dickel, G.; Marinho, R.; Oliveira, P.; Faria, F.

10.1101/538165 — plant biology — Posted on 2019-02-01

2678 Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter

Gillet, L.; Guichard, S.; Essers, M. C.; Rougier, J.-S.; Abriel, H.

10.1101/536789 — physiology — Posted on 2019-02-01

2679 Contextual cues as modifiers of cTBS effects on indulgent eating

Safati, A. B.; Hall, P. A.

10.1101/538439 — neuroscience — Posted on 2019-02-01

2680 Horizontally transmitted symbiont populations in deep-sea mussels are genetically isolated

Romero Picazo, D.; Dagan, T.; Ansorge, R.; Petersen, J. M.; Dubilier, N.; Kupczok, A.

10.1101/536854 — microbiology — Posted on 2019-02-01

2681 Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Moudgil, A.; Wilkinson, M. N.; Chen, X.; He, J.; Cammack, A. J.; Vasek, M. J.; Lagunas, T.; Qi, Z.; Morris, S. A.; Dougherty, J. D.; Mitra, R. D.

10.1101/538553 — genomics — Posted on 2019-02-01

2682 MAUI-seq: Multiplexed, high-throughput amplicon diversity profiling using unique molecular identifiers

Fields, B.; Moeskjaer, S.; Friman, V.-P.; Andersen, S. U.; Young, P. W.

10.1101/538587 — ecology — Posted on 2019-02-01

2683 Testing models of mRNA localization reveals robustness regulated by reducing transport between cells

Harrison, J. U.; Parton, R. M.; Davis, I.; Baker, R. E.

10.1101/533133 — developmental biology — Posted on 2019-02-01

2684 A pivotal role for Nrf2 in endothelial detachment- implications for endothelial erosion of stenotic plaques

Satta, S.; McElroy, M.; Langford-Smith, A.; Ferris, G.; Teasdale, J. E.; Kim, Y.; Niccoli, G.; Tanjeko, A. T.; Serre, J.; Hazell, G. G.; Sala Newby, G.; Wang, P.; Johnson, J. L.; Humphries, M. J.; Gayan-Ramirez, G.; Libby, P.; Crea, F.; Degens, H.; Gijsen, F.; Johnson, T.; Keshmiri, A.; Alexander, Y.; Newby, A. C.; White, S. J.

10.1101/537852 — cell biology — Posted on 2019-02-01

2685 MAGMA: inference of sparse microbial association networks

Cougoul, A. P.; Bailly, X.; Wit, E. C.

10.1101/538579 — bioinformatics — Posted on 2019-02-01

2686 Analysis of solid-state heparin samples by ATR-FTIR spectroscopy

Devlin, A.; Mycroft-West, C.; Guerrini, M.; Yates, E.; Skidmore, M.

10.1101/538074 — biochemistry — Posted on 2019-02-01

2687 Task errors drive memories that improve sensorimotor adaptation.

Leow, L.-A.; Marinovic, W.; de Rugy, A.; Carroll, T. J.

10.1101/538348 — neuroscience — Posted on 2019-02-01

2688 Trajectory of brain maturation in adolescent individuals at familial risk of mood disorder

de Nooij, L.; Harris, M. A.; Hawkins, E. L.; Shen, X.; Clarke, T.-K.; Chan, S. W. Y.; Ziermans, T. B.; McIntosh, A. M.; Whalley, H. C.

10.1101/537951 — neuroscience — Posted on 2019-02-01

2689 Cxcr4 desensitization is an essential regulatory mechanism controlling the extra-follicular B cell response.

Alouche, N.; Bonaud, A.; Rondeau, V.; Nguyen, J.; Cricks, E.; Setterblad, N.; Mahevas, M.; Balabanian, K.; Espeli, M.

10.1101/537761 — immunology — Posted on 2019-02-01

2690 Islands of retroelements are the major components of Drosophila centromeres

Chang, C.-H.; Chavan, A.; Palladino, J.; Wei, X.; Martins, N. M. C.; Santinello, B.; Chen, C.-C.; Erceg, J.; Beliveau, B. J.; Wu, C.-T.; Larracuente, A. M.; Mellone, B.

10.1101/537357 — genomics — Posted on 2019-02-01

2691 Lifelong genetically lowered sclerostin and risk of cardiovascular disease.

Bovijn, J.; Krebs, K.; Chen, C.-Y.; Boxall, R.; Censin, J. C.; Ferreira, T.; Pulit, S. L.; Glastonbury, C. A.; Laber, S.; Millwood, I. Y.; Lin, K.; Li, L.; Chen, Z.; Milani, L.; Walters, R. G.; Mägi, R.; Neale, B. M.; Lindgren, C. M.; Holmes, M. V.

10.1101/531004 — genetics — Posted on 2019-02-01

2692 An olfactory receptor gene underlies reproductive isolation in perfume-collecting orchid bees

Brand, P.; Hinojosa-Diaz, I. A.; Ayala, R.; Daigle, M.; Yurrita Obiols, C. L.; Eltz, T.; Ramirez, S. R.

10.1101/537423 — evolutionary biology — Posted on 2019-02-01

2693 Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer

Corona, R. I.; Seo, J.-H.; Lin, X.; Hazelett, D. J.; Reddy, J.; Abassi, F.; Lin, Y. G.; Mhawech-Fauceglia, P. Y.; Lester, J.; Shah, S. P.; Huntsman, D. G.; Gusev, A.; Karlan, B. Y.; Berman, B. P.; Freedman, M. L.; Gayther, S. A.; Lawrenson, K.

10.1101/537886 — cancer biology — Posted on 2019-02-01

2694 Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences

Schneider, T. D.; Jejjala, V.

10.1101/538025 — bioinformatics — Posted on 2019-02-01

2695 Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine

Belo, Y.; Mielko, Z.; Nudelman, H.; Afek, A.; Ben-David, O.; Shahar, A.; Zarivach, R.; Gordan, R.; Arbely, E.

10.1101/537696 — biochemistry — Posted on 2019-02-01

2696 Phantom limb pain intensity is associated with generalized hyperalgesia

Fuchs, X.; Diers, M.; Trojan, J.; Kirsch, P.; Milde, C.; Bekrater-Bodmann, R.; Rance, M.; Foell, J.; Andoh, J.; Becker, S.; Flor, H.

10.1101/538207 — neuroscience — Posted on 2019-02-01

2697 Selective attention modifies weights of distinct visual signals in human decision making

Rangelov, D.; Mattingley, J. B.

10.1101/537910 — neuroscience — Posted on 2019-02-01

2698 Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

Aparicio, O. M.; Zhang, H.; Petrie, M. V.; He, Y.; Peace, J. M.; Chiolo, I. E.

10.1101/538363 — molecular biology — Posted on 2019-02-01

2699 The 'hidden side' of spin labeled oligonucleotides: Molecular Dynamics study focusing on the EPR-silent components of base pairing

Dantu, S. C.; Sicoli, G.; Höbartner, C.; Groenhof, G.

10.1101/537324 — biophysics — Posted on 2019-02-01

2700 Structure-based methyl resonance assignment with MethylFLYA

Pritisanac, I.; Würz, J.; Alderson, R.; Güntert, P.

10.1101/538272 — biophysics — Posted on 2019-02-01

2701 Global variability of the human IgG glycome

Stambuk, J.; Nakic, N.; Vuckovic, F.; Pucic-Bakovic, M.; Razdorov, G.; Trbojevic-Akmacic, I.; Novokmet, M.; Keser, T.; Vilaj, M.; Pavic, T.; Gudelj, I.; Simurina, M.; Song, M.; Wang, H.; Pericic Salihovic, M.; Campbell, H.; Rudan, I.; Kolcic, I.; Eller, L. A.; McKeigue, P.; Robb, M. L.; Halfvarson, J.; Kurtoglu, M.; Annese, V.; Skaric-Juric, T.; Molokhia, M.; Polasek, O.; Hayward, C.; Kibuuka, H.; Thaqi, K.; Gieger, C.; Nitayaphan, S.; Spector, T.; Wang, Y.; Tillin, T.; Chaturvedi, N.; Wilson, J. F.; Schanfield, M.; Filipenko, M.; Wang, W.; Lauc, G.

10.1101/535237 — biochemistry — Posted on 2019-02-01

2702 GIT2 is dispensable for normal learning and memory function due to a predominant brain GIT2 splice variant that evades GIT/PIX complexes.

Toth, K.; Martyn, A. C.; Bastrikova, N.; Kim, W.; Rodriguiz, R. M.; Ahmed, U.; Schmalzigaug, R.; Dudek, S. M.; Wetsel, W. C.; Premont, R. T.

10.1101/538223 — animal behavior and cognition — Posted on 2019-02-01

2703 The Evolutionary Dynamics of Cooperation in Collective Search

Novaes Tump, A.; Wu, C. M.; Bouhlel, I.; Goldstone, R. L.

10.1101/538447 — animal behavior and cognition — Posted on 2019-02-01

2704 Temporal control of inhibition via muscarinic acetylcholine receptor signaling generates ON and OFF selectivity in a simple visual circuit

Bo, Q.; Humberg, T.-H.; Kim, A.; Kim, H.; Short, J.; Diao, F.; White, B. H.; Sprecher, S. G.; Yuan, Q.

10.1101/535427 — neuroscience — Posted on 2019-02-01

2705 Chk1 Phosphorylates Cdh1 to Promote SCFβTRCP-Dependent Degradation of Cdh1 During S-Phase

Pal, D.; Torres, A. E.; Messina, A. L.; Dickson, A.; De, K.; Willard, B.; Venere, M.; Summers, M. K.

10.1101/535799 — cell biology — Posted on 2019-02-01

2706 A statistical modeling framework to assess cross-frequency coupling while accounting for confounding effects

Nadalin, J. K.; Martinet, L.-E.; Blackwood, E.; Lo, M.-C.; Widge, A. S.; Cash, S. S.; Eden, U.; Kramer, M. A.

10.1101/519470 — neuroscience — Posted on 2019-02-01

2707 Most of transcriptional alterations in glioma result from DNA-methylation independent mechanisms

Court, F.; Le Boiteux, E.; Fogli, A.; Müller-Barthelemy, M.; Vaurs-Barriere, C.; Chautard, E.; Pereira, B.; Biau, J.; Kemeny, J.-L.; Khalil, T.; Karayan-Tapon, L.; Verrelle, P.; arnaud, P.

10.1101/516997 — molecular biology — Posted on 2019-02-01

2708 Effect of Adhesion and Substrate Elasticity on Neutrophil Extracellular Trap Formation

Erpenbeck, L.; Gruhn, A. L.; Kudryasheva, G.; Guenay, G.; Meyer, D.; Neubert, E.; Grandke, J.; Schoen, M. P.; Rehfeldt, F.; Kruss, S.

10.1101/508366 — biophysics — Posted on 2019-02-01

2709 Ncl1 mediated metabolic rewiring is critical during metabolic stress

Bhat, A.; Chakraborty, R.; Adlakha, K.; Agam, G.; Chakraborty, K.; Sengupta, S.

10.1101/529578 — biochemistry — Posted on 2019-02-01

2710 Collateral development and arteriogenesis in hindlimbs of domestic swine after ligation of arterial inflow

Patel, N. S.; Gao, Y.; Aravind, S.; Fugelstad, M.; Casale, G.; Pipinos, I. I.; Carlson, M. A.

10.1101/491928 — physiology — Posted on 2019-02-01

2711 Inflammation and matrix metalloproteinase 9 (Mmp-9) regulate photoreceptor regeneration in the adult zebrafish

Silva, N. J.; Nagashima, M.; Li, J.; Kakuk-Atkins, L.; Ashrafzadeh, M.; Hyde, D. R.; Hitchcock, P. F.

10.1101/518365 — neuroscience — Posted on 2019-02-01

2712 Phosphatidylinositol 3,5-Bisphosphate regulates Ca2+ Transport During Yeast Vacuolar Fusion through Activation of the Ca2+ ATPase Pmc1

Miner, G. E.; Sullivan, K. D.; Guo, A.; Starr, M. L.; Ellis, E. C.; Jones, B. C.; Fratti, R. A.

10.1101/533067 — biochemistry — Posted on 2019-02-01

2713 Inference of Nonlinear Spatial Subunits by Spike-Triggered Clustering in Primate Retina

Shah, N. P.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Goetz, G.; Litke, A.; Sher, A.; Simoncelli, E. P.; Chichilnisky, E. J.

10.1101/496422 — neuroscience — Posted on 2019-02-01

2714 GIFT - A Global Inventory of Floras and Traits for macroecology and biogeography

Weigelt, P.; Koenig, C.; Kreft, H.

10.1101/535005 — ecology — Posted on 2019-02-01

2715 Reconstruction of 1,000 projection neurons reveals new cell types and organization of long-range connectivity in the mouse brain

Winnubst, J.; Bas, E.; Ferreira, T. A.; Wu, Z.; Economo, M. N.; Edson, P.; Arthur, B. J.; Bruns, C.; Rokicki, K.; Schauder, D.; Olbris, D. J.; Murphy, S. D.; Ackerman, D. G.; Arshadi, C.; Baldwin, P.; Blake, R.; Elsayed, A.; Hasan, M.; Ramirez, D.; Dos Santos, B.; Weldon, M.; Zafar, A.; Dudmann, J. T.; Gerfen, C. R.; Hantman, A. W.; Korff, W.; Sternson, S. M.; Spruston, N.; Svoboda, K.; Chandrashekar, J.

10.1101/537233 — neuroscience — Posted on 2019-02-01

2716 Blood-brain barrier dysfunction in aging induces hyper-activation of TGF-beta signaling and chronic yet reversible neural dysfunction

Senatorov, V. V.; Friedman, A. R.; Milikovsky, D. Z.; Ofer, J.; Saar-Ashkenazy, R.; Charbash, A.; Jahan, N.; Chin, G.; Mihaly, E.; Lin, J. M.; Ramsay, H. J.; Moghbel, A.; Preininger, M. K.; Eddings, C. R.; Harrison, H. V.; Patel, R.; Shen, Y.; Ghanim, H.; Sheng, H.; Veksler, R.; Sudmant, P.; Becker, A.; Hart, B.; Rogawski, M.; Dillin, A.; Friedman, A.; Kaufer, D.

10.1101/537431 — neuroscience — Posted on 2019-02-01

2717 3D Chromatin Architecture Remodeling during Human Cardiomyocyte Differentiation Reveals A Role Of HERV-H In Demarcating Chromatin Domains

Zhang, Y.; Li, T.; Preissl, S.; Grinstein, J.; Farah, E.; Destici, E.; Lee, A. Y.; Chee, S.; Qiu, Y.; Ma, K.; Ye, Z.; Zhu, Q.; Huang, H.; Hu, R.; Fang, R.; Yu, L.; Belmonte, J. C.; Wu, J.; Evans, S.; Chi, N.; Ren, B.

10.1101/485961 — genomics — Posted on 2019-02-01

2718 The coiled coil domain of DEF6 facilitates formation of large vesicle-like, cytoplasmic aggregates that trap the P-body marker DCP1 and exhibit prion-like features

Cheng, H.; Sablitzky, F.

10.1101/538082 — molecular biology — Posted on 2019-02-01

2719 Pannexin-1 Channels govern the Generation of Necroptotic small Extracellular Vesicles

Douanne, T.; Andre-Gregoire, G.; Feyeux, M.; Hulin, P.; Gavard, J.; Bidere, N.

10.1101/537753 — cell biology — Posted on 2019-02-01

2720 retroLEAP: rAAV-based retrograde trans-synaptic labeling, expression and perturbation

Reinert, J. K.; Sonntag, I.; Sonntag, H.; Sprengel, R.; Pelzer, P.; Lessle, S.; Kaiser, M.; Kuner, T.

10.1101/537928 — neuroscience — Posted on 2019-02-01

2721 Sonic hedgehog signaling in astrocytes mediates cell-type-specific synaptic organization

Hill, S. A.; Blaeser, A.; Coley, A.; Xie, Y.; Shepard, K. A.; Harwell, C.; Gao, W.-J.; Garcia, A. D. R.

10.1101/537860 — neuroscience — Posted on 2019-02-01

2722 Synaptotagmin-1 and Doc2b exhibit distinct membrane remodeling mechanisms

Sorkin, R.; Marchetti, M.; Logtenberg, E.; Piontek, M.; Kerklingh, E.; Brand, G.; Voleti, R.; Rizo, J.; Roos, W. H.; Groffen, A. J.; Wuite, G. J. L.

10.1101/538405 — biophysics — Posted on 2019-02-01

2723 Mechanical activation of TRPV4 channels controls albumin reabsorption by proximal tubule cells.

Gualdani, R.; Seghers, F.; Yerna, X.; Schakman, O.; Tajeddine, N.; Achouri, Y.; Tissir, F.; Devuyst, O.; Gailly, P.

10.1101/537944 — physiology — Posted on 2019-02-01

2724 Transposon-mediated, cell type-specific transcription factor recording in the mouse brain

Cammack, A. J.; Moudgil, A.; Lagunas, T.; Vasek, M. J.; Shabsovich, M.; He, J.; Chen, X.; Wilkinson, M. N.; Miller, T. M.; Mitra, R. D.; Dougherty, J. D.

10.1101/538504 — neuroscience — Posted on 2019-02-01

2725 Current clinical use of polygenic scores will risk exacerbating health disparities

Martin, A. R.; Kanai, M.; Kamatani, Y.; Okada, Y.; Neale, B. M.; Daly, M. J.

10.1101/441261 — genetics — Posted on 2019-02-01

2726 Theoretical modeling on CRISPR-coded cell lineages: efficient encoding and optimal reconstruction

Sugino, K.; Garcia Marques, J.; Espinosa Medina, I.; Lee, T.

10.1101/538488 — developmental biology — Posted on 2019-02-01

2727 Fracking and Ostwald ripening position the lumen of the mouse blastocyst

Dumortier, J.; Le Verge-Serandour, M.; Tortorelli, A.-F.; Mielke, A.; de Plater, L.; Turlier, H.; Maitre, J.-L.

10.1101/537985 — developmental biology — Posted on 2019-02-01

2728 A primal role for balance in the development of coordinated locomotion

Ehrlich, D. E.; Schoppik, D.

10.1101/538546 — neuroscience — Posted on 2019-02-01

2729 Impaired M-current in KCNQ2 Encephalopathy Evokes Dyshomeostatic Modulation of Excitability

Simkin, D.; Searl, T. J.; Piyevsky, B. N.; Forrest, M.; Williams, L. A.; Joshi, V.; Zhang, H.; Ryan, S. J.; Schwake, M.; Robertson, G. L.; Penzes, P.; Laux, L. C.; McManus, O. B.; Dempsey, G. T.; Millichap, J. J.; George, A. L.; Kiskinis, E.

10.1101/538371 — neuroscience — Posted on 2019-02-01

2730 Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids

Huang, Q.; Chan, K. Y.; Tobey, I. G.; Chan, Y. A.; Poterba, T.; Boutros, C. L.; Balazs, A. B.; Daneman, R.; Bloom, J. M.; Seed, C.; Deverman, B. E.

10.1101/538421 — neuroscience — Posted on 2019-02-01

2731 Converging roles of glutamate receptors in domestication and prosociality

O'Rourke, T.; Boeckx, C.

10.1101/439869 — evolutionary biology — Posted on 2019-02-01

2732 Defining the seafloor microbiome of the Gulf of Mexico and its response to oil perturbation

Overholt, W. A.; Schwing, P.; Hastings, D.; Hollander, D. J.; Kostka, J. E.

10.1101/236950 — ecology — Posted on 2019-02-01

2733 Staufen2 mediated RNA recognition and localization requires combinatorial action of multiple domains

Heber, S.; Gaspar, I.; Tants, J.-N.; Günther, J.; Fernandez Moya, S. M.; Janowski, R.; Ephrussi, A.; Sattler, M.; Niessing, D.

10.1101/396994 — biochemistry — Posted on 2019-02-01

2734 Multiscale analysis of a non-periodic epidemic time series using wavelet transform

Gaudart, J.; Rebaudet, S.; Texier, G.; Barrais, R.; Piarroux, R.; Giorgi, R.

10.1101/535146 — epidemiology — Posted on 2019-02-01

2735 Bleeding in cardiac patients prescribed antithrombotic drugs: Electronic health record phenotyping algorithms, incidence, trends and prognosis

Pasea, L.; Chung, S.-C.; Pujades-Rodriguez, M.; Shah, A. D.; Alvarez-Madrazo, S.; Allan, V.; Teo, J. T.; Bean, D.; Sofat, R.; Dobson, R.; Banerjee, A.; Patel, R. S.; Timmis, A.; Denaxas, S.; Hemingway, H.

10.1101/538249 — epidemiology — Posted on 2019-02-01

2736 Occupation and Parkinson disease in Women's Health Initiative Observational Study

Burstyn, I.; LaCroix, A. Z.; Litvan, I.; Wallace, R. B.; Checkoway, H.

10.1101/535732 — epidemiology — Posted on 2019-02-01

2737 More accuracy estimation of the worm burden in the ascariasis of children in Kinshasa

Tshima, G. K.

10.1101/537126 — epidemiology — Posted on 2019-02-01

2738 What is the explanation for Plasmodium vivax malarial recurrence? Experience of Parasitology Unit of Kinshasa University Hospital of 1982-1983 and 2000-2009

Tshima, G. K.

10.1101/537027 — epidemiology — Posted on 2019-02-01

2739 Hospitalizations associated with respiratory syncytial virus (RSV) and influenza in children, including children having a diagnosis of asthma

Goldstein, E.; Finelli, L.; O'Halloran, A.; Liu, P.; Karaca, Z.; Steiner, C. A.; Viboud, C.; Lipsitch, M.

10.1101/161067 — epidemiology — Posted on 2019-02-01

2740 Feedback training can increase detection of happiness in ambiguous facial expressions in children and adults with autism spectrum disorders

Griffiths, S.; Attwood, A. S.; Penton-Voak, I. S.; Jarrold, C.; Munafo, M. R.

10.1101/524322 — clinical trials — Posted on 2019-02-01

2741 Implanted Nerve Electrical Stimulation allows to Selectively Restore Hand and Forearm Movements in Patients with a Complete Tetraplegia

Tigra, W.; Azevedo, C.; Teissier, J.; Gelis, A.; Coulet, B.; Divoux, J.-L.; Guiraud, D.

10.1101/534362 — clinical trials — Posted on 2019-02-01

2742 Mapping changes in the spatiotemporal distribution of lumpy skin disease virus

Machado, G.; Korennoy, F.; Alvarez, J.; Picasso-Risso, C.; Perez, A.; VanderWaal, K.

10.1101/531343 — epidemiology — Posted on 2019-02-01

2743 National HIV testing and diagnosis coverage in sub-Saharan Africa: a new modeling tool for estimating the \"first 90\" from program and survey data

Maheu-Giroux, M.; Marsh, K.; Doyle, C.; Godin, A.; Laniece Delaunay, C.; Johnson, L. F.; Jahn, A.; Abo, K.; Mbofana, F.; Boily, M.-C.; Buckeridge, D. L.; Hankins, C.; Eaton, J. W.

10.1101/532010 — epidemiology — Posted on 2019-02-01

2744 Outpatient antibiotic stewardship interventions: geographic scale and associations between antibiotic use and resistance

Olesen, S. W.; Lipsitch, M.; Grad, Y. H.

10.1101/536714 — epidemiology — Posted on 2019-02-01

2745 A Model-Based Cost-Effectiveness Analysis of an Exercise Program for Lung Cancer Survivors Following Curative-Intent Treatment

Ha, D.; Kerr, J.; Ries, A. L.; Fuster, M. M.; Lippman, S. M.; Murphy, J. D.

10.1101/533281 — epidemiology — Posted on 2019-02-01

2746 HIV infection and incidence of cardiovascular diseases: an analysis of a large healthcare database

Alonso, A.; Barnes, A. E.; Guest, J.; Shah, A.; Shao, I. Y.; Marconi, V.

10.1101/534024 — epidemiology — Posted on 2019-02-01

2747 Upscaling surveillance of tick-borne pathogens in the French Caribbean islands

Gondard, M.; Delannoy, S.; Pinarello, V.; Aprelon, R.; Devillers, E.; Galon, C.; Pradel, J.; Vayssier-Taussat, M.; Albina, E.; MOUTAILLER, S.

10.1101/532457 — epidemiology — Posted on 2019-02-01

2748 Determinants of the population health distribution, or why are risk factor-body mass index associations larger at the upper end of the BMI distribution?

Bann, D.; Fitzsimons, E.; Johnson, W.

10.1101/537829 — epidemiology — Posted on 2019-02-01

2749 Countries are out of step with international recommendations for tuberculosis testing, treatment, and care: Findings from a 29-country survey of policy adoption and implementation

Saran, K.; Masini, T.; Chikwanha, I.; Paton, G.; Scourse, R.; Kahn, P.; Sahu, S.; Perrin, C.; Ditiu, L.; Lynch, S.

10.1101/533851 — epidemiology — Posted on 2019-02-01

2750 Detection of malaria in insectary-reared Anopheles gambiae using near-infrared spectroscopy

Ferreira Maia, M.; Kapulu, M.; Muthui, M.; Wagah, M.; Ferguson, H.; Dowell, F.; Baldini, F.; Ranford-Cartwright, L.

10.1101/533802 — epidemiology — Posted on 2019-02-01

2751 Dose-specific effectiveness of 7- and 13-valent pneumococcal conjugate vaccines against vaccine-serotype Streptococcus pneumoniae colonization: a matched, case-control study

Lewnard, J. A.; Givon-Lavi, N.; Dagan, R.

10.1101/532085 — epidemiology — Posted on 2019-02-01

2752 Genetically Increased Telomere Length and Aging-related Physical and Cognitive Traits in the UK Biobank

Demanelis, K.; Tong, L.; Pierce, B. L.

10.1101/538124 — epidemiology — Posted on 2019-02-01

2753 Lead optimisation of dehydroemetine for repositioned use in malaria

Panwar, P.; Burusco, K.; Abubaker, M.; Matthews, H.; Gutnov, A.; Fernandez-Alvaro, E.; Bryce, R.; Wilkinson, J.; Nirmalan, N. J.

10.1101/538413 — microbiology — Posted on 2019-02-01

2754 Whole genome sequencing and comparative genomic analysis reveal novel allelic variations unique to a purple colored rice landrace (Oryza sativa ssp. indica cv. Purpleputtu)

Lachagari, V. B. R.; Gupta, R.; Lekkala, S. P.; Mahadevan, L.; Kuriakose, B.; Chakravartty, N.; Katta, A. V. S. K. M.; Santhosh, S.; Reddy, A. R.; Thomas, G.

10.1101/536326 — genomics — Posted on 2019-02-01

2755 Characteristics of Beta Waveform Shape in Parkinson's Disease Detected with Scalp Electroencephalography

Jackson, N.; Cole, S. R.; Voytek, B.; Swann, N. C.

10.1101/534396 — neuroscience — Posted on 2019-02-01

2756 Polygenic Adaptation: From sweeps to subtle frequency shifts

Hoellinger, I.; Pennings, P.; Hermisson, J.

10.1101/450759 — evolutionary biology — Posted on 2019-02-01

2757 Subcortical Shape Alterations in Major Depressive Disorder: Findings from the ENIGMA Major Depressive Disorder Working Group

Ho, T. C.; Gutman, B.; Pozzi, E.; Grabe, H. J.; Hosten, N.; Wittfeld, K.; Völzke, H.; Baune, B.; Dannlowski, U.; Förster, K.; Grotegerd, D.; Redlich, R.; Jansen, A.; Kircher, T.; Krug, A.; Meinert, S.; Nenadic, I.; Opel, N.; Dinga, R.; Veltman, D. J.; Schnell, K.; Veer, I.; Walter, H.; Gotlib, I. H.; Sacchet, M. D.; Aleman, A.; Groenewold, N. A.; Stein, D. J.; Li, M.; Walter, M.; Jahanshad, N.; Thompson, P. M.; Sämann, P. G.; Schmaal, L.

10.1101/534370 — neuroscience — Posted on 2019-02-01

2758 Antibiotic treatment drives the diversification of the human gut resistome

Li, J.; Rettedal, E.; van der Helm, E.; Ellabaan, M. M. H.; Panagiotou, I.; Sommer, M. O. A.

10.1101/537670 — microbiology — Posted on 2019-02-01

2759 LuxUS: Detecting differential DNA methylation using generalized linear mixed model with spatial correlation structure

Halla-aho, V.; Lähdesmäki, H.

10.1101/536722 — bioinformatics — Posted on 2019-02-01

2760 The properties of 5-methyltetrahydrofolate dehydrogenase (MthfD) and its role in the tetrahydrofolate (THF)-dependent dicamba demethylation system in Rhizorhabdus dicambivorans Ndbn-20

Yao, S.-G.; Chen, L.; Yang, Z.; Yao, L.; Zhu, J.; Qiu, J.; Wang, G.; He, J.

10.1101/537639 — microbiology — Posted on 2019-02-01

2761 Conservation of N-hydroxy-pipecolic acid-mediated systemic acquired resistance in crop plants

Holmes, E.; Chen, Y. C.; Sattely, E.; Mudgett, M. B.

10.1101/537597 — plant biology — Posted on 2019-02-01

2762 Freeze-frame imaging of synaptic activity using SynTagMA

Perez-Alvarez, A.; Fearey, B.; Schulze, C.; O'Toole, R. J.; Moeyaert, B.; Mohr, M. A.; Arganda-Carreras, I.; Yang, W.; Wiegert, J. S.; Schreiter, E. R.; Gee, C. E.; Hoppa, M. B.; Oertner, T. G.

10.1101/538041 — neuroscience — Posted on 2019-02-01

2763 Maternal Protection in Childhood is Associated with Amygdala Reactivity and Structural Connectivity in Adulthood

Farber, M. J.; Kim, M. J.; Knodt, A. R.; Hariri, A. R.

10.1101/535823 — neuroscience — Posted on 2019-02-01

2764 Plasmodium knowlesi clinical isolates from Malaysia show extensive diversity and strong differential selection pressure at the merozoite surface protein 7D (MSP7D)

Ahmed, M. A.; Quan, F.-S.

10.1101/537621 — genetics — Posted on 2019-02-01

2765 Modulating the human functional connectome using deep brain stimulation

Horn, A.; Wenzel, G.; Irmen, F.; Huebl, J.; Li, N.; Neumann, W.-J.; Krause, P.; Bohner, G.; Scheel, M.; Kuehn, A. A.

10.1101/537712 — neuroscience — Posted on 2019-02-01

2766 Peripheral axonal ensheathment is regulated by Ral GTPase and the exocyst complex

Silva Rodrigues, J. F.; Patricio-Rodrigues, C. F.; Sousa-Xavier, V. O.; Augusto, P. M.; Fernandes, A. C.; Farinho, A. R.; Teodoro, R. O.

10.1101/537969 — neuroscience — Posted on 2019-02-01

2767 Saffron (Crocus sativus) is an autotriploid that evolved in Attica (Greece) from wild Crocus cartwrightianus

Nemati, Z.; Harpke, D.; Gemicioglu, A.; Kerndorff, H.; Blattner, F. R.

10.1101/537688 — evolutionary biology — Posted on 2019-02-01

2768 Functional intra-operative guidance of the cavernous nerve network using near-infrared cyanine voltage-sensitive dye imaging: relevance for nerve-sparing radical prostatectomy

Kang, J.; Le, H. N. D.; Karakus, S.; Malla, A. P.; Harraz, M. M.; Kang, J. U.; Burnett, A. L.; Boctor, E. M.

10.1101/537274 — biophysics — Posted on 2019-02-01

2769 Time Series Experiment Design Under One-Shot Sampling: The Importance of Condition Diversity

Kang, X.; Hajek, B.; Wu, F.; Hanzawa, Y.

10.1101/537548 — systems biology — Posted on 2019-02-01

2770 Neuronal activity and learning in local cortical networks are modulated by the action-perception state

Engelhard, B.; Darshan, R.; Ozeri-Engelhard, N.; Israel, Z.; Werner-Reiss, U.; Hansel, D.; Bergman, H.; Vaadia, E.

10.1101/537613 — neuroscience — Posted on 2019-02-01

2771 Deep Brain Stimulation of the Ventromedial Prefrontal Cortex Disrupts Consolidation of Fear Memories

Tan, S. Z. K.; Poon, C. H.; Chan, Y.-S.; Lim, L. W.

10.1101/537514 — neuroscience — Posted on 2019-02-01

2772 A real-time PCR for the differentiation of typhoidal and non-typhoidal Salmonella

Nair, S.; Patel, V.; Hickey, T.; Maguire, C.; Greig, D. R.; Lee, W.; Godbole, G.; Grant, K.; Chattaway, M. A.

10.1101/537654 — microbiology — Posted on 2019-02-01

2773 A novel QTL conferring Fusarium crown rot resistance located on chromosome arm 6HL in barley

Gao, S.; Zheng, Z.; Hu, H.; Shi, H.; Ma, J.; Liu, Y.; Wei, Y.; Zheng, Y.; Zhou, M.; Liu, C.

10.1101/537605 — plant biology — Posted on 2019-02-01

2774 GIFT - A Global Inventory of Floras and Traits for macroecology and biogeography

Weigelt, P.; Koenig, C.; Kreft, H.

10.1101/535005 — ecology — Posted on 2019-02-01

2775 The phage L capsid decoration protein has a novel OB-fold and an unusual capsid binding strategy

Newcomer, R. L.; Schrad, J. R.; Gilcrease, E. B.; Casjens, S. R.; Feig, M.; Teschke, C. M.; Alexandrescu, A.; Parent, K. N.

10.1101/420992 — biophysics — Posted on 2019-02-01

2776 Synthetic pluripotent bacterial stem cells

Molinari, S.; Shis, D. L.; Chappell, J.; Igoshin, O. A.; Bennett, M. R.

10.1101/436535 — synthetic biology — Posted on 2019-02-01

2777 Germline genetic variants associated with leukocyte-genes predict tumor recurrence in breast cancer patients

Milanese, J.-S.; Tibiche, C.; Zou, J.; Meng, Z. G.; Nantel, A.; Drouin, S.; Marcotte, R.; Wang, E.

10.1101/312355 — cancer biology — Posted on 2019-02-01

Archive, 2019-02