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Archive, 2023-08

2 A synthetic biology approach to transgene expression
Leftwich, P. T.; Purcell, J. C.; Anderson, M. A. E.; Fragkoudis, R.; Basu, S.; Lycett, G. T.; Alphey, L.
10.1101/2023.08.31.555539 — synthetic biology — Posted on 2023-08-31
3 Epidemiological modeling of SARS-CoV-2 in white-tailed deer (Odocoileus virginianus) reveals conditions for introduction and widespread transmission
Rosenblatt, E. G.; Cook, J. D.; DiRenzo, G. V.; Grant, E. H. C.; Arce, F.; Pepin, K. M.; Rudolph, F. J.; Runge, M. C.; Shriner, S.; Walsh, D. P.; Mosher, B. A.
10.1101/2023.08.30.555493 — ecology — Posted on 2023-08-31
4 The crystal structure of bacteriophage lambda RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins
Adams, M. C.; Schiltz, C. J.; Sun, J.; Hosford, C. J.; Johnson, V. M.; Pan, H.; Borbat, P. P.; Freed, J. H.; Thomason, L. C.; Court, C.; Court, D. L.; Chappie, J. S.
10.1101/2023.08.31.555690 — microbiology — Posted on 2023-08-31
6 Genome-wide CRISPRi screens reveal the essentialome and determinants for susceptibility to dalbavancin in Staphylococcus aureus
Liu, X.; de Bakker, V.; Heggenhougen, M. V.; Marli, M. T.; Froynes, A. H.; Salehian, Z.; Porcellato, D.; Morales Angeles, D.; Veening, J.-W.; Kjos, M.
10.1101/2023.08.30.555613 — microbiology — Posted on 2023-08-31
7 Genome-wide screens reveal shared and strain-specific genes that facilitate enteric colonization by Klebsiella pneumoniae
Cheung, B.; Alisoltanidehkordi, A.; Kochan, T. J.; Lebrun-Corbin, M.; Nozick, S.; Axline, C. M.; Bachta, K. E. R.; Ozer, E. A.; Hauser, A. R.
10.1101/2023.08.30.555643 — microbiology — Posted on 2023-08-31
10 Fibronectin: a natural barrier against prion infection
Garza, M. C.; Kang, S. G.; Kim, C.; Monleon, E.; van der Merwe, J.; Kramer, D. A.; Fahlman, R.; Sim, V.; Aiken, J.; McKenzie, D.; Cortez, L. M.; Wille, H.
10.1101/2023.08.31.555658 — biochemistry — Posted on 2023-08-31
11 Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19
Padi, S. K.; Vos, M. R.; Godek, R. J.; Fuller, J. R.; Kruse, T.; Hein, J. B.; Nilsson, J.; Kelker, M. S.; Page, R.; Peti, W.
10.1101/2023.08.31.555365 — biochemistry — Posted on 2023-08-31
12 Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1
Mycroft-West, C. J.; Abdelkarim, S.; Duyvesteyn, H. M. E.; Gandhi, N. S.; Skidmore, M. A.; Owens, R. J.; Wu, L.
10.1101/2023.08.30.555497 — biochemistry — Posted on 2023-08-31
13 Evolutionarily related host and microbial pathways regulate fat desaturation
Fox, B.; Helf, M.; Burkhardt, R.; Artyukhin, A.; Curtis, B.; Palomino, D. F.; Chaturbedi, A.; Tauffenberger, A.; Wrobel, C. J.; Zhang, Y.; Lee, S. S.; Schroeder, F.
10.1101/2023.08.31.555782 — biochemistry — Posted on 2023-08-31
14 Structural basis of aggregate binding by the AAA+ disaggregase ClpG
Katikaridis, P.; Simon, B.; Jenne, T.; Moon, S.; Lee, C.; Hennig, J.; Mogk, A.
10.1101/2023.08.31.555675 — biochemistry — Posted on 2023-08-31
15 Sm-like protein Rof inhibits transcription termination factor Rho by binding site obstruction and conformational insulation
Said, N.; Finazzo, M.; Hilal, T.; Wang, B.; Selinger, T. L.; Gjorgjevikj, D.; Artsimovitch, I.; Wahl, M. C.
10.1101/2023.08.30.555460 — biochemistry — Posted on 2023-08-31
18 A Small Tau Fragment Specifically Templates Four Repeat Tau Aggregates Through Multiple Generations
Longhini, A. P.; DuBose, A.; Lobo, S.; Vijayan, V.; Bai, Y.; Keane, E.; Sala-Jarque, J.; Nikitina, A.; Carrettiero, D.; Unger, M.; Sclafani, O.; Fu, V.; Vigers, M.; Buee, L.; Landrieu, I.; Shell, S.; Shea, J. E.; Han, S.; Kosik, K. S.
10.1101/2023.08.31.555649 — molecular biology — Posted on 2023-08-31
19 Tracer-based lipidomics identifies novel disease-specific biomarkers in mitochondrial β-oxidation disorders
Schwantje, M.; Mosegaard, S.; Knottnerus, S. J. G.; van Klinken, J. B.; Wanders, R. J.; van Lenthe, H.; Hermans, J.; IJlst, L.; Denis, S. W.; Jaspers, Y. R. J.; Fuchs, S. A.; Houtkooper, R.; Ferdinandusse, S.; Vaz, F. M.
10.1101/2023.08.31.555571 — molecular biology — Posted on 2023-08-31
20 EfpA is required for re-growth of Mycobacterium tuberculosis following isoniazid exposure
Roberts, A. H.; Moon, C. W.; Faulkner, V.; Kendall, S. L.; Waddell, S.; Bacon, J.
10.1101/2023.08.31.555697 — microbiology — Posted on 2023-08-31
22 Computational exploration of the global microbiome for antibiotic discovery
Celio Dias, S.-J.; Marcelo D. T., T.; Yiqian, D.; Alvaro, R. d. R.; Thomas S.B., S.; Hui, C.; Anthony, F.; Kuhn, M.; Chengkai, Z.; Amy, H.; Jelena, S.; Anna, V.; Xing-Ming, Z.; Peer, B.; Jaime, H.-C.; Cesar, d. l. F.-N.; Luis Pedro, C.
10.1101/2023.08.31.555663 — microbiology — Posted on 2023-08-31
26 Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core
Bessonne, M.; Morel, J.; Nevers, Q.; Ballandras-Colas, A.; Grange, M.; Roussel, A.; Crepin, T.; Delmas, B.
10.1101/2023.08.31.555659 — microbiology — Posted on 2023-08-31
27 XBB.1.5 Spike Protein COVID-19 Vaccine Induces Broadly Neutralizing and Cellular Immune Responses Against EG.5.1 and Emerging XBB Variants
Patel, N.; Trost, J. F.; Guebre-Xabier, M.; Zhou, H.; Norton, J.; Jiang, D.; Cai, Z.; Zhu, M.; Marchese, A. M.; Greene, A. M.; Mallory, R. M.; Kalkeri, R.; Dubovsky, F.; Smith, G.
10.1101/2023.08.30.554497 — immunology — Posted on 2023-08-31
28 Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 enhances antibody evasion and ACE2 binding
Jian, F.; Yang, S.; Yu, Y.; Song, W.; Yisimayi, A.; Chen, X.; Xu, Y.; Wang, P.; Yu, L.; Wang, J.; Liu, L.; Niu, X.; Wang, J.; Xiao, T.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Wang, Y.; Cao, Y. R.
10.1101/2023.08.30.555211 — immunology — Posted on 2023-08-31
32 Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
Perampalam, P.; MacDonald, J. I.; Zakirova, K.; Passos, D.; Ramos-Valdes, Y.; Hervieu, M.; Mehlen, P.; Rottapel, R.; Gibert, B.; Correa, R.; Shepherd, T.; Dick, F.
10.1101/2023.08.29.555435 — cancer biology — Posted on 2023-08-31
36 A microfluidic model of colonocyte-microbiota interaction mimicking the colorectal cancer microenvironment
Penarete-Acosta, D.; Stading, R.; Emerson, L.; Horn, M.; Chakraborty, S.; Han, A.; Jayaraman, A.
10.1101/2023.08.29.555442 — bioengineering — Posted on 2023-08-31
38 Saccharomycotina yeasts defy longstanding macroecological patterns
David, K. T.; Harrison, M.-C.; Opulente, D. A.; LaBella, A. L.; Wolters, J. F.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Pennell, M.; Hittinger, C. T.; Rokas, A.
10.1101/2023.08.29.555417 — ecology — Posted on 2023-08-31
40 Cooperative progression of colitis and leukemia modulated by clonal hematopoiesis via PTX3/IL-1β pro-inflammatory signaling
He, H.; Wen, Y.; Liu, J.; Huo, Q.; Yu, H.; Jin, W.; Wang, Z.; Du, G.; Du, J.; Wang, H.; Zhao, Z.; Cai, Z.
10.1101/2023.08.29.555330 — immunology — Posted on 2023-08-31
43 Cue-Induced Drug Seeking and Its Association with Craving and Dependence in Cigarette Smokers
Solinas, M.; Chauvet, C.; Lafay-Chebassier, C.; Vanderkam, P.; Barillot, L.; Moeller, S. J.; Goldstein, R. Z.; Noel, X.; Jaafari, N.; Chatard, A.
10.1101/2023.08.30.555462 — neuroscience — Posted on 2023-08-31
44 Genome assembly of the bearded iris Iris pallida Lam.
Bruccoleri, R. E.; Oakeley, E. J.; Faust, A. M. E.; Altorfer, M.; Dessus-Babus, S.; Burckhardt, D.; Oertli, M.; Naumann, U.; Petersen, F.; Wong, J.
10.1101/2023.08.29.555454 — plant biology — Posted on 2023-08-31
46 Passive surveillance for shrimp pathogens in Penaeus vannamei submitted from 3 Regions of Latin America
Intriago, P.; Medina, A.; Cercado, N.; Arteaga, K.; Montenegro, A.; Burgos, M.; Espinoza, J.; Brock, J. A.; McInstosh, R.; Flegel, T.
10.1101/2023.08.29.555391 — pathology — Posted on 2023-08-31
47 PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression
Schmidt, C.; Cohen, S.; Gudenas, B. L.; Husain, S.; Carlson, A.; Westelman, S.; Wang, L.; Phillips, J. J.; Northcott, P. A.; Weiss, W. A.; Schwer, B.
10.1101/2023.08.29.555389 — cancer biology — Posted on 2023-08-31
49 Water and chloride as allosteric inhibitors in WNK kinase osmosensing
Goldsmith, E. J.; Teixeira, L. R.; Radha, A.; Humphreys, J. M.; He, H.
10.1101/2023.08.29.555411 — biophysics — Posted on 2023-08-31
51 PVN microglia via P2Y12 transmit hemodynamic signal to promote sympathetic excitation in hypertension
Wei, B.; Cheng, G.; Li, L.; Sun, Q.; Bi, Q.; Lu, C.; Yin, C.; Chen, N.; Hu, M.; Lu, H.; Hu, Z.; Mao, G.; Gu, Y.; Wan, S.; Liu, X.; Shen, X. Z.; Shi, P.
10.1101/2023.08.29.555298 — neuroscience — Posted on 2023-08-31
52 Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence
Pietrogrande, G.; Shaker, M.; Stednitz, S.; Soheilmoghaddam, F.; Aguado, J.; Morrison, S.; Zambrano, S.; Tabassum, T.; Javed, I.; Cooper-White, J. J.; Davis, T.; Scott, E.; O'Brien, T.; Wolvetang, E. J.
10.1101/2023.08.29.555421 — neuroscience — Posted on 2023-08-31
53 Delivering biochemicals with precision using bioelectronic devices enhanced with feedback control
Marquez, G. A.; Dechiraju, H.; Baniya, P.; Li, H.; Tebyani, M.; Pansodtee, P.; Jafari, M.; Teodorescu, M.; Rolandi, M.; Gomez, M.
10.1101/2023.08.29.555386 — systems biology — Posted on 2023-08-31
54 Diversity of Bathyarchaeia viruses in metagenomes and virus-encoded CRISPR system components
Duan, C.; Liu, Y.; Liu, Y.; Cai, M.; Liu, L.; Zhang, R.; Zeng, Q.; Koonin, E. V.; Krupovic, M.; Li, M.
10.1101/2023.08.24.554615 — microbiology — Posted on 2023-08-31
55 Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systems
Tammaro, A.; Daniels, E. G.; Hu, I. M.; t Hart, K. C.; Reid, K.; Juni, R. P.; Butter, L.; Vasam, G.; Kamble, R. S.; Jongejan, A.; Aviv, R. I.; Roelofs, J. J. T. H.; Aronica, E.; Boon, R. A.; Menzies, K. J.; Houtkooper, R.; Janssens, G. E.
10.1101/2023.08.29.555280 — pathology — Posted on 2023-08-31
56 The Diversity of NLRs in Brassica rapa Pan-genome
Liu, S.; Zhu, Y.; Ke, B.; Wang, J.; Peng, X.; Zhang, S.; Zhao, R.; Wang, H.; Luo, J.; Li, J.; Zheng, Y.; Huang, T.; Wang, S.; Lang, Z.; Wang, L.; Sun, X.; Wang, C.
10.1101/2023.08.29.555307 — genomics — Posted on 2023-08-31
58 Human-brown bear conflicts in Turkey are driven by increased human presence around protected areas
Sikdokur, E.; Naderi, M.; Celtik, E.; Aytekin, M. C. K.; Kusak, J.; Saglam, I. K.; Sekercioglu, C. H.
10.1101/2023.08.29.555317 — ecology — Posted on 2023-08-31
60 Different Purkinje cell pathologies cause specific patterns of progressive ataxia in mice
Jaarsma, D.; Birkisdottir, M.; van Vossen, R.; Oomen, D.; Akhiyat, O.; Vermeij, W.; Koekkoek, S.; De Zeeuw, C.; Bosman, L. W.
10.1101/2023.08.29.555378 — neuroscience — Posted on 2023-08-31
61 Altered reactivity to threatening stimuli in Drosophila models of Parkinson's disease, revealed by a trial-based assay
Kajtor, M.; Billes, V. A.; Kiraly, B.; Stabb, H.; Sviatko, K.; Ujvari, E.; Balazsfi, D.; Seidenbecher, S. E.; Kvitsiani, D.; Vellai, T.; Hangya, B.
10.1101/2023.08.29.555311 — neuroscience — Posted on 2023-08-31
68 qMaLioffG: A single green fluorescent protein FLIM indicator enabling quantitative imaging of endogenous ATP
Arai, S.; Itoh, H.; Vu, C. Q.; Nakayama, M.; Oshima, M.; Morita, A.; Okamoto, K.; Okuda, S.; Teranishi, A.; Osawa, M.; Tamura, Y.; Nonoyama, S.; Takuma, M.; Fujie, T.; Sarker, S. R.; Sudhaharan, T.; Kiya, T.; Lane, E. B.; Kitaguchi, T.
10.1101/2023.08.29.555275 — biophysics — Posted on 2023-08-31
69 Liquid Crystalline Layering and Divalent Cations Cooperatively Enhance DNA Condensation
Kodikara, S. G.; Gyawali, P.; Gleeson, J. T.; Jakli, A.; Sprunt, S.; Balci, H.
10.1101/2023.08.29.555320 — biophysics — Posted on 2023-08-31
70 High-speed 3D DNA-PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography
Wisna, G. B. M.; Sukhareva, D.; Zhao, J.; Satyabola, D.; Matthies, M.; Roy, S.; Sulc, P.; Yan, H.; Hariadi, R. F.
10.1101/2023.08.29.555281 — biophysics — Posted on 2023-08-31
72 Synergistic Fusion of Graph and Transformer Features for Enhanced Molecular Property Prediction
Sai Prakash, M. V.; Nareddy, S. R.; Parab, G.; Venkatesan, V.; Vaddina, V.; Gopalakrishnan, S.
10.1101/2023.08.28.555089 — bioinformatics — Posted on 2023-08-31
75 Modelling Osteoarthritis pathogenesis through Mechanical Loading in an Osteochondral Unit-on-Chip
Mainardi, A.; Boersch, A.; Occhetta, P.; Ivanek, R.; Ehrbar, M.; Krattiger, L. A.; Oertle, P.; Loparic, M.; Martin, I.; Rasponi, M.; Barbero, A.
10.1101/2023.08.29.555292 — bioengineering — Posted on 2023-08-31
77 High quality genome of the Mountain hare (Lepus timidus) with new chromosome level scaffolding
Michell, C.; Collins, J.; Fekete, Z.; Tapanainen, R.; Wood, J. M. D.; Goffart, S.; Pohjoismaki, J. L. O.
10.1101/2023.08.29.555262 — genomics — Posted on 2023-08-31
78 High-resolution diploid 3D genome reconstruction using Pore-C data
Chen, Y.; Lin, Z.-B.; Wang, S.; Wu, B.; Niu, L.-J.; Zhong, J.-Y.; Sun, Y.-M.; Bai, X.; Liu, L.-R.; Xie, W.; Luo, R.; Hou, C.; Luo, F.; Xiao, C.-L.
10.1101/2023.08.29.555243 — genomics — Posted on 2023-08-31
79 Open access-enabled evaluation of epigenetic age acceleration in colorectal cancer and development of a classifier with diagnostic potential.
Widayati, T. A.; Schneider, J.; Panteleeva, K.; Chernysheva, E.; Hrbkova, N.; Beck, S.; Voloshin, V.; Chervova, O.
10.1101/2023.08.29.555284 — genomics — Posted on 2023-08-31
86 Aberrant activation of the innate immune sensor PKR by self dsRNA is prevented by direct interaction with ADAR1
Sinigaglia, K.; Cherian, A.; Vukic, D.; Melicherova, J.; Linhartova, P.; Du, Q.; Zerad, L.; Stejskal, S.; Malik, R.; Prochazka, J.; Bondurand, N.; Sedlacek, R.; O'Connell, M. A.; Keegan, L. P.
10.1101/2023.08.29.555105 — immunology — Posted on 2023-08-31
87 Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity
Montorsi, L.; Pitcher, M. J.; Zhao, Y.; Demonti, A.; Tull, T. J.; Dionisi, C.; Dhami, P.; Ellis, R. J.; Bishop, C.; Sanderson, J.; Jain, S.; D'Cruz, D.; Gibbons, D.; Winkler, T. H.; Bemark, M.; Ciccarelli, F. D.; Spencer, J.
10.1101/2023.08.29.555265 — immunology — Posted on 2023-08-31
90 Heterogeneity of synaptic connectivity in the fly visual system
Cornean, J.; Molina-Obando, S.; Gur, B.; Bast, A.; Ramos-Traslosheros, G.; Chojetzki, J.; Lorsch, L.; Ioannidou, M.; Taneja, R.; Schnaitmann, C.; Silies, M.
10.1101/2023.08.29.555204 — neuroscience — Posted on 2023-08-31
91 Evidence for vagal sensory neural involvement in influenza pathogenesis and disease
McGovern, A.; Verzele, N. A. J.; Chua, B. Y.; Short, K. R.; Moe, A. A. K.; Edwards, I. N.; Bielefeldt-Ohmann, H.; Hulme, K. D.; Noye, E. C.; Tong, M. Z. W.; Reading, P. C.; Trewella, M. W.; Mazzone, S. B.
10.1101/2023.08.29.555274 — neuroscience — Posted on 2023-08-31
94 Opportunities for risk-taking during play alters cognitive performance and prefrontal inhibitory signalling in rats of both sexes
Bijlsma, A.; Birza, E.; Pimentel, T.; Maranus, J.; van Gaans, M.; van 't Klooster, J.; Baars, A.-M.; Achterberg, M. E. J.; Lesscher, H. M. B.; Vanderschuren, L. J. M. J.; Wierenga, C. J.
10.1101/2023.08.29.555263 — neuroscience — Posted on 2023-08-31
96 Visual looming is a primitive for human emotion
Thieu, M. K. N.; Ayzenberg, V.; Lourenco, S. F.; Kragel, P. A.
10.1101/2023.08.29.555380 — neuroscience — Posted on 2023-08-31
100 Assessing an age-old ecogeographical rule in nightjars across the full annual cycle
Skinner, A. A.; Korpach, A. M.; Akesson, S.; Bakermans, M.; Benson, T. J.; Brigham, R. M.; Conway, G. J.; Davy, C. M.; Evens, R.; Fraser, K. C.; Hedenström, A.; Henderson, I. G.; Honkala, J.; Jacobsen, L. B.; Norevik, G.; Thorup, K.; Tonra, C. M.; Vitz, A.; Ward, M. P.; Knight, E.
10.1101/2023.08.30.555574 — zoology — Posted on 2023-08-31
103 Imaging of existing and newly translated proteins elucidates the mechanisms of sarcomere turnover
Douvdevany, G.; Erlich, I.; Haimovich-Caspi, L.; Prondzynski, M.; Pricolo, M. R.; Alegre-Cebollada, J.; Linke, W. A.; Carrier, L.; Kehat, I.
10.1101/2023.08.31.555653 — cell biology — Posted on 2023-08-31
104 USP7/Maged1-Mediated H2A Monoubiquitination in the Paraventricular Thalamus: An Epigenetic Mechanism Involved in Cocaine Use Disorder
Cheron, J.; Beccari, L.; Hague, P.; Icick, R.; Despontin, C.; Carusone, T.; Defrance, M.; Bhogaraju, S.; Martin-Garcia, E.; Capellan, R.; Maldonado, R.; Vorspan, F.; Bonnefont, J.; de Kerchove d'Exaerde, A.
10.1101/2022.11.16.516716 — neuroscience — Posted on 2023-08-31
108 Female reed warblers in social pairs with low MHC dissimilarity achieve higher MHC compatibility through random extra-pair matings
Halupka, L.; O'Connor, E. A.; Strandh, M.; Sztwiertnia, H.; Klimczuk, E.; Hasselquist, D.; Westerdahl, H.
10.1101/2023.04.17.537178 — ecology — Posted on 2023-08-31
109 CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia.
Andres-San Roman, J. A.; Gordillo-Vazquez, C.; Franco-Barranco, D.; Morato, L.; Fernandez-Espartero, C. H.; Baonza, G.; Tagua, A.; Vicente-Munuera, P.; Palacios, A. M.; Gavilan, M. P.; Martin-Belmonte, F.; Annese, V.; Gomez-Galvez, P.; Arganda-Carreras, I.; Escudero, L. M.
10.1101/2023.01.05.522724 — developmental biology — Posted on 2023-08-31
111 Detecting the ecological footprint of selection
Luiselli, J.; Overcast, I.; Rominger, A.; Ruffley, M.; Morlon, H.; Rosindell, J.
10.1101/2021.05.11.442553 — ecology — Posted on 2023-08-31
113 Breakdown and rejuvenation of aging brain energy metabolism
Shichkova, P.; Coggan, J. S.; Boci, E.; Favreau, C. P. H.; Antonel, S. M.; Markram, H.; Keller, D.
10.1101/2023.08.30.555341 — neuroscience — Posted on 2023-08-31
117 Novel YAP1/TAZ pathway inhibitors identified through phenotypic screening with potent anti-tumor activity via blockade of GGTase-I / Rho-GTPase signaling
Graham, K.; Lienau, P.; Bader, B.; Prechtl, S.; Naujoks, J.; Lesche, R.; Kuehnlenz, J.; Brzezinka, K.; Potze, L.; Zanconato, F.; Nicke, B.; Montebaur, A.; Bone, W.; Golfier, S.; Kaulfuss, S.; Kopitz, C.; Pilari, S.; Steuber, H.; Hayat, S.; Kamburov, A.; Steffen, A.; Schlicker, A.; Buchgraber, P.; Braeuer, N.; Font, N. A.; Heinrich, T.; Kuhnke, L.; Nowak-Reppel, K.; Stresemann, C.; Steigemann, P.; Walter, A. O.; Blotta, S.; Ocker, M.; Lakner, A.; Mumberg, D.; Eis, K.; Piccolo, S.; Lange, M.
10.1101/2023.08.30.555331 — cancer biology — Posted on 2023-08-31
118 Dynamic coordination of the lever-arm swing of human myosin II in thick filaments on actin
Fukunaga, H.; Washio, T.; Fujita, K.; Ohmachi, M.; Takagi, H.; Ikezaki, K.; Yanagida, T.; Iwaki, M.
10.1101/2023.08.30.554051 — biophysics — Posted on 2023-08-31
119 Size dependent steady-state saturation limit in biomolecular transport through nuclear membranes
Padinhare kandiyil, S.; Meethale Mangalassery, B.; J, H.; Joseph, T.; Patincharath, N.; Varier, G. K.
10.1101/2023.08.02.551582 — biophysics — Posted on 2023-08-31
125 De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments
Eloff, K.; Kalogeropoulos, K.; Morell, O.; Mabona, A.; Berg Jespersen, J.; Williams, W.; van Beljouw, S.; Skwark, M.; Hougaard Laustsen, A.; Brouns, S. J. J.; Ljungars, A.; Schoof, E. M.; Van Goey, J.; auf dem Keller, U.; Beguir, K.; Lopez Carranza, N.; Jenkins, T. P.
10.1101/2023.08.30.555055 — bioinformatics — Posted on 2023-08-31
132 Linking genomic prediction for muscle fat content in Atlantic salmon to underlying changes in lipid metabolism regulation
Harvey, T. N.; Dvergedal, H.; Gronvold, L.; Jin, Y.; Odegard, J.; Korsvoll, S. A.; Knutsen, T. M.; Hvidsten, T. R.; Sandve, S. R.
10.1101/2023.08.29.555338 — genomics — Posted on 2023-08-31
136 Lineage maintenance due to assortative mating but not ecological divergence in a sympatric sibling species pair
Irvine, M.; Stewart, Z.; Kumaran, N.; Manawaduge, C. G.; Balagawi, S.; Missenden, B.; Starkie, M.; Clarke, A. R.; Hurwood, D. A.; Prentis, P.
10.1101/2023.08.30.555036 — evolutionary biology — Posted on 2023-08-31
141 Modular control of time and space during vertebrate axis segmentation
Seleit, A.; Brettell, I.; Fitzgerald, T. W.; Vibe, C.; Loosli, F.; Wittbrodt, J.; Naruse, K.; Birney, E.; Aulehla, A.
10.1101/2023.08.30.555457 — developmental biology — Posted on 2023-08-31
142 A distinct class of hematopoietic stem cells develop from the human yellow bone marrow
Nguyen, T. T.; Loureiro, Z. Y.; Desai, A.; DeSouza, T.; Joyce, S.; Khair, L.; Samant, A.; Cirka, H.; Solivan-Rivera, J.; Ziegler, R.; Brehm, M.; Messina, L. M.; Corvera, S.
10.1101/2023.08.29.555167 — developmental biology — Posted on 2023-08-31
143 Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells
Yao, Y.; Lou, X.; Jin, L.; Li, J.; Liu, J.; Chen, Y.; Cheng, S.; Zhao, T.; Ke, S.; Zhang, L.; Zhang, P.; Xu, Y.; He, L.; Li, H.
10.1101/2023.08.03.551799 — cell biology — Posted on 2023-08-31
144 E-cigarette vapour induces cellular senescence in primary lung fibroblasts and may contribute to lung pathology
Bozier, J.; Wang, B.; de Vries, M.; Brandsma, C.-A.; van den Berge, M.; Timens, W.; Heijink, I. H.; Oliver, B. G. G.; Woldhuis, R. R.
10.1101/2023.08.30.555286 — cell biology — Posted on 2023-08-31
147 An amphipathic helix facilitates direct membrane binding of Mycoplasma FtsZ
Dutta, S.; Poddar, S. M.; Chakraborty, J.; Srinivasan, R.; Gayathri, P.
10.1101/2023.08.29.555414 — microbiology — Posted on 2023-08-31
150 Spatiotemporal development of the human T follicular helper cell response to Influenza vaccination
Schattgen, S.; Turner, J. S.; Ghonim, M. A.; Crawford, J. C.; Schmitz, A. J.; Kim, H.; Zhou, J. Q.; Awad, W.; Kim, W.; McIntire, K. M.; Haile, A.; Klebert, M. K.; Suessen, T.; Middleton, W. D.; Teefey, S. A.; Presti, R. M.; Ellebedy, A.; Thomas, P.
10.1101/2023.08.29.555186 — immunology — Posted on 2023-08-31
152 Real-time feedback reduces participant motion during task-based fMRI
Rogers, C. S.; Jones, M. S.; McConkey, S.; McLaughlin, D. J.; Peelle, J. E.
10.1101/2023.01.12.523791 — neuroscience — Posted on 2023-08-31
153 Single-cell analysis of Rohon-Beard neurons implicates Fgf signaling in axon maintenance and cell survival
Tuttle, A. M.; Royer, L. J.; Kelly, J. J.; Wen, H.; Calistri, N.; Heiser, L. M.; Nechiporuk, A. V.
10.1101/2023.08.26.554953 — neuroscience — Posted on 2023-08-31
154 CCR7+ CD4 T Cell Immunosurveillance Disrupted in Chronic SIV-Induced Neuroinflammation in Rhesus Brain.
Elizaldi, S. R.; Hawes, C. E.; Verma, A.; Dinasarapu, A. R.; Lakshmanappa, Y. S.; Schlegel, B. T.; Rajasundaram, D.; Li, J.; Johnson, B. P. D.-; Ma, Z.-M.; Beckman, D.; Ott, S.; Lifson, J. D.; Morrison, J. H.; Iyer, S. S.
10.1101/2023.08.28.555037 — neuroscience — Posted on 2023-08-31
155 Transcriptional dysregulation and impaired neuronal activity in FMR1 knock-out and Fragile X patients iPSC-derived models.
Maussion, G.; Rocha, C.; Abdian, N.; Yang, D.; Turk, J.; Valenzuela, D. C.; Pimentel, L.; You, Z.; Morquette, B.; Nicouleau, M.; Deneault, E.; Higgins, S.; Chen, C. X.- Q.; Reintsch, W.; Ho, S.; Soubannier, V.; Lepine, S.; Modrusan, Z.; Lund, J.; Stephenson, W.; Schubert, R.; Durcan, T.
10.1101/2023.08.30.554628 — neuroscience — Posted on 2023-08-31
157 Prefrontal coding of learned and inferred knowledge during REM & NREM sleep
Abdou, K.; H. Aly, M.; Ibrahim, A.; Choko, K.; Nomoto, M.; Okubo-Suzuki, R.; Muramatsu, S.-i.; Inokuchi, K.
10.1101/2021.04.08.439095 — neuroscience — Posted on 2023-08-31
159 Opto4E-BP, an optogenetic tool for inducible, reversible, and cell type-specific inhibition of translation initiation
Alapin, J. M.; Mohamed, M. S.; Shrestha, P.; Khaled, H. G.; Vorabyeva, A. G.; Bowling, H. L.; Oliveira, M. M.; Klann, E.
10.1101/2023.08.30.554643 — neuroscience — Posted on 2023-08-31
161 Catalyst: Fast and flexible modeling of reaction networks
Loman, T.; Ma, Y.; Ilin, V.; Gowda, S.; Korsbo, N.; Yewale, N.; Rackauckas, C. V.; Isaacson, S. A.
10.1101/2022.07.30.502135 — systems biology — Posted on 2023-08-31
162 Lignin, glutathione and kinases play important roles in Paspalum regnellii defense against spittlebug (Mahanarva spectabilis) attack
Begnami, I. S.; Aono, A. H.; Graciano, D. S.; Carmello-Guerreiro, S. M.; Ferreira, R. C. U.; Malago, W.; Gusmao, M. R.; Souza, A. P.; Vigna, B. B. Z.
10.1101/2023.08.29.555367 — plant biology — Posted on 2023-08-31
163 Enhanced metabolic detoxification is associated with fluroxypyr resistance in Bassia scoparia
Todd, O. E.; Patterson, E.; Westra, E. P.; Simoes Araujo, A. L.; Kramer, W. B.; Dayan, F. E.; Gaines, T. A.
10.1101/2023.08.29.554743 — plant biology — Posted on 2023-08-31
165 Substrate-Specific Function of PNPLA3 Facilitates Hepatic VLDL-Triglyceride Secretion During Stimulated Lipogenesis
Johnson, S. M.; Bao, H.; McMahon, C.; Chen, Y.; Burr, S.; Anderson, A.; Madeyski-Bengtson, K.; Linden, D.; Han, X.; Liu, J.
10.1101/2023.08.30.553213 — physiology — Posted on 2023-08-31
168 Rheological behavior of Pluronic/Pluronic diacrylate hydrogels used for bacteria encapsulation
Bhusari, S.; Hoffmann, M.; Herbeck-Engel, P.; Sankaran, S.; Wilhelm, M.; del Campo, A.
10.1101/2023.03.29.534703 — bioengineering — Posted on 2023-08-31
169 Mechanistic insights into GTP-dependence and kinetic polarity of FtsZ filament assembly
Chakraborty, J.; Poddar, S. M.; Dutta, S.; Bahulekar, V.; Harne, S.; SRINIVASAN, R.; Gayathri, P.
10.1101/2022.10.13.512043 — biochemistry — Posted on 2023-08-31
174 Not so local: the population genetics of convergent adaptation in maize and teosinte.
Tittes, S.; Lorant, A.; McGinty, S.; Holland, J. B.; Sanchez-Gonzalez, J. d. J.; Seetharam, A. S.; Tenaillon, M. I.; Ross-Ibarra, J.
10.1101/2021.09.09.459637 — evolutionary biology — Posted on 2023-08-30
178 The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis
Tejeda Munoz, N.; Azbazdar, Y.; Monka, J.; Binder, G.; Ayala, R.; Dayrit, A.; O'Brien, N.; De Robertis, E. M.
10.1101/2023.06.02.543509 — developmental biology — Posted on 2023-08-31
179 Influence of pseudo-green water on growth, colouration, and survival in European lobster (Homarus gammarus) larvae
Bell, M. E.; Grady, J. O.; Domech, P. C.; Frontaura, E. R.; Hinchcliffe, J.; Davies, S. J.; McCusker, S.; Wan, A. H. L.
10.1101/2023.08.30.555547 — developmental biology — Posted on 2023-08-31
181 The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity
Wakasa, T.; Iimori, M.; Nonaka, K.; Harada, A.; Ohkawa, Y.; Kikutake, C.; Suyama, M.; Kobunai, T.; Matsuoka, K.; Tsunekuni, K.; Kataoka, Y.; Ochiiwa, H.; Miyadera, K.; Sagara, T.; Oki, E.; Ohdo, S.; Maehara, Y.; Kitao, H.
10.1101/2023.08.30.555463 — cell biology — Posted on 2023-08-30
182 A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Lim, K.; Rutherford, E. N.; Sun, D.; Van den Boomen, D. J.; Edgar, J. R.; Bang, J.; Matesic, L. E.; Lee, J.-H.; Lehner, P. J.; Marciniak, S. J.; Rawlins, E. L.; Dickens, J. A.
10.1101/2023.08.30.555522 — cell biology — Posted on 2023-08-30
183 Metabolomic rearrangement controls the intrinsic microbial response to temperature changes
Knapp, B.; Willis, L.; Gonzalez, C.; Vashistha, H.; Touma, J. J.; Tikhonov, M.; Ram, J.; Salman, H.; Elias, J. E.; Huang, K. C.
10.1101/2023.07.22.550177 — cell biology — Posted on 2023-08-30
184 Unraveling human hematopoietic progenitor cell diversity through association with intrinsic regulatory factors
Favaro, P.; Glass, D. R.; Borges, L.; Reemar, R. B.; Reynolds, W.; Ho, D.; Bruce, T.; Tebaykin, D.; Scalon, V. M.; Shestopalov, I.; Bendall, S. C.
10.1101/2023.08.30.555623 — cell biology — Posted on 2023-08-31
185 Metabolic regulation of misfolded protein import into mitochondria
Wang, Y.; Ruan, L.; Zhu, J.; Zhang, X.; Chang, A.; Tomaszewski, A.; Li, R.
10.1101/2023.03.29.534670 — cell biology — Posted on 2023-08-31
187 The A53T mutation in α-synuclein enhances pro-inflammatory activation in human microglia
Krzisch, M. A.; Yuan, B.; Chen, W.; Osaki, T.; Fu, D.; Garrett-Engele, C. M.; Svoboda, D. S.; Andrykovich, K. R.; Sur, M.; Jaenisch, R.
10.1101/2023.08.29.555300 — neuroscience — Posted on 2023-08-31
188 A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity
Dedhia, P.; Sivakumar, H.; Rodriguez, M. A.; Nairon, K. G.; Zent, J. M.; Zheng, X.; Jones, K.; Popova, L.; Leight, J. L.; Skardal, A.
10.1101/2023.01.24.525287 — cancer biology — Posted on 2023-08-30
190 CD22L Conjugation to Insulin Attenuates Insulin-Specific B cell Activation
Apley, K. D.; Griffith, A. S.; Downes, G.; Ross, P. A.; Farrell, M. P.; Kendall, P. L.; Berkland, C. J.
10.1101/2023.06.13.544802 — bioengineering — Posted on 2023-08-30
191 Expanding the Drosophila toolkit for dual control of gene expression
Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J.; Risbeck, A.; Forman, C.; Villalta, C.; Hu, Y.; Perrimon, N.
10.1101/2023.08.15.553399 — genetics — Posted on 2023-08-30
194 Modulation of riboflavin biosynthesis and utilization in mycobacteria
Chengalroyen, M. D.; Mehaffy, C.; Lucas, M.; Raphela, M. L.; Warner, D. F.; Lewinsohn, D.; Lewinsohn, D.; Dobos, K.; Mizrahi, V.
10.1101/2023.08.30.555301 — molecular biology — Posted on 2023-08-30
197 Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth
Zhang, Y.; Chen, K.; Tang, S. C.; Cai, Y.; Nambu, A.; See, Y. X.; Fu, C.; Raju, A.; Lebeau, B.; Ling, Z.; Mutwil, M.; Lakshmanan, M.; Osato, M.; Tergaonkar, V.; Fullwood, M. J.
10.1101/2023.08.29.555291 — molecular biology — Posted on 2023-08-30
198 Evidence of target-mediated miRNA degradation in Drosophila ovarian cell culture
Akulenko, N.; Mikhaleva, E.; Marfina, S.; Kornyakov, D.; Bobrov, V.; Arapidi, G.; Shender, V.; Ryazansky, S.
10.1101/2023.08.30.555489 — molecular biology — Posted on 2023-08-30
200 Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus.
Greigert, V.; Saraav, I.; Son, J.; Dayao, D.; Antia, A.; Tzipori, S.; Witola, W.; Stappenbeck, T. S.; Ding, S.; Sibley, L. D.
10.1101/2023.08.30.555581 — microbiology — Posted on 2023-08-30
204 Microbial cell factory optimisation using genome-wide host-pathway interaction screens
Cachera, P. P.-Y. J.; Kurt, N. C.; Ropke, A.; Strucko, T.; Mortensen, U. H.; Jensen, M. K.
10.1101/2023.08.30.555557 — synthetic biology — Posted on 2023-08-30
206 Functional characterization of gene regulatory elements and neuropsychiatric disease-associated risk loci in iPSCs and iPSC-derived neurons
Yang, X.; Jones, I. R.; Chen, P. B.; Yang, H.; Ren, X.; Zheng, L.; Li, B.; Li, Y. E.; Sun, Q.; Wen, J.; Beaman, C.; Cui, X.; Li, Y.; Wang, W.; Hu, M.; Ren, B.; Shen, Y.
10.1101/2023.08.30.555359 — genetics — Posted on 2023-08-30
208 Metagenomic analysis of individual mosquitos reveals the ecology of insect viruses
Pan, Y.-f.; Zhao, H.; Gou, Q.-y.; Shi, P.-b.; Tian, J.-h.; Feng, Y.; Li, K.; Yang, W.-h.; Wu, D.; Tang, G.; Zhang, B.; Ren, Z.; Peng, S.; Luo, G.-y.; Le, S.-j.; Xin, G.-y.; Wang, J.; Hou, X.; Peng, M.-w.; Kong, J.-b.; Chen, X.-x.; Yang, C.-h.; Mei, S.-q.; Liao, Y.-q.; Cheng, J.-x.; Wang, J.; n/a, C.; Wu, Y.-h.; Wang, J.-b.; An, T.; Huang, X.; Eden, J.-S.; Li, J.; Guo, D.; Liang, G.; Jin, X.; Holmes, E. C.; Li, B.; Wang, D.; Li, J.; Wu, W.-c.; Shi, M.
10.1101/2023.08.28.555221 — ecology — Posted on 2023-08-30
210 Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase
Haugen, R. J.; Barnier, C.; Elrod, N. D.; Luo, H.; Jensen, M. K.; Ji, P.; Smibert, C. A.; Lipshitz, H. D.; Wagner, E. J.; Freddolino, P. L.; Goldstrohm, A.
10.1101/2023.08.29.555372 — molecular biology — Posted on 2023-08-30
211 DNA barcoding revealed a high percentage of mislabeling in commercial fish products: the first empirical survey in South Texas
Tommasi, R. B.; Lamia, S. M.; Van, D.; Estrada, I.; Kuchler, Z. L.; Ramsey, D.; Tamang, J.; Kaneko, G.; Ehsan, H.
10.1101/2023.08.29.555441 — molecular biology — Posted on 2023-08-30
216 Diversity and community structure of anaerobic gut fungi in the rumen of wild and domesticated herbivores
Meili, C.; Tag ElDein, M. A.; Jones, A. L.; Moon, C. D.; Andrews, C.; Kirk, M. R.; Janssen, P. H.; J. Yeoman, C.; Grace, S.; Borgogna, J.-L. C.; Foote, A. P.; Nagy, Y. I.; Khashef, M. T.; Yassin, A.; Elshahed, M. S.; Youssef, N. H.
10.1101/2023.08.29.555426 — microbiology — Posted on 2023-08-30
218 Immune Evasion and Membrane Fusion of SARS-CoV-2 XBB Subvariants EG.5.1 and XBB.2.3
Faraone, J. N.; Qu, P.; Goodarzi, N.; Zheng, Y.-M.; Carlin, C.; Saif, L. J.; Oltz, E. M.; Xu, K.; Jones, D.; Gumina, R. J.; Liu, S.-L.
10.1101/2023.08.30.555188 — immunology — Posted on 2023-08-30
221 Integration of Mass Cytometry and Mass Spectrometry Imaging for Spatially Resolved Single Cell Metabolic Profiling
Nunes, J. B.; Ijsselsteijn, M. E.; Abdelaal, T.; Ursem, R.; van der Ploeg, M.; Everts, B.; Mahfouz, A.; Heijs, B.; de Miranda, N.
10.1101/2023.08.29.555282 — cancer biology — Posted on 2023-08-30
222 Molecular Property Diagnostic Suite for COVID-19 (MPDSCOVID-19): An open access disease specific drug discovery portal
Sastry, G. N.; Priyadarsinee, L.; Jamir, E.; Nagamani, S.; Mahanta, H. J.; Kumar, N.; John, L.; Sarma, H.; Kumar, A.; Gaur, A. S.; Sahoo, R.; Vaikundamani, S.; Murugan, N. A.; Priyakumar, U. D.; Raghava, G. P. S.; Bharatam, P.; Ramakrishnan, P.; Subramanian, V.; Sastry, G. M.
10.1101/2023.08.29.555437 — bioinformatics — Posted on 2023-08-30
224 OptoPI3K, genetic code expansion, and click chemistry reveal mechanisms underlying reciprocal regulation between TRPV1 and PI3K
Koh, D.-S.; Stratiievska, A.; Jana, S.; Otto, S. C.; Swanson, T. M.; Nhim, A.; Carlson, S.; Raza, M.; Naves, L. A.; Senning, E. N.; Mehl, R.; Gordon, S. E.
10.1101/2023.08.29.555449 — physiology — Posted on 2023-08-30
225 KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo
Najumudeen, A. K.; Fey, S. K.; Millet, L. M.; Ford, C. A.; Gilroy, K.; Gunduz, N.; Ridgway, R. A.; Anderson, E.; Strathdee, D.; Clark, W.; Nixon, C.; Morton, J. P.; Campbell, A. D.; Sansom, O. J.
10.1101/2023.08.29.555396 — cancer biology — Posted on 2023-08-30
226 Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover
Hvorecny, K. L.; Sladewski, T. E.; De La Cruz, E. M.; Kollman, J. M.; Heaslip, A. T.
10.1101/2023.08.29.555340 — biophysics — Posted on 2023-08-30
229 Rab7a activation promotes degradation of select tight junction proteins at the blood-brain barrier after ischemic stroke
Cottarelli, A.; Shahriar, S.; Arac, A.; Glendinning, M.; Tuohy, M. C.; Prochilo, G.; Neal, J. B.; Edinger, A.; Agalliu, D.
10.1101/2023.08.29.555373 — cell biology — Posted on 2023-08-30
230 Logic Gate Activated Lysosome Targeting DNA Nanodevice for Controlled Proteins Degradation
Shang, Y.; Zhu, L.; Xiao, Y.; Du, S.; Ji, R.; Li, B.; Chen, J.; Deng, S.; Ren, K.
10.1101/2023.08.29.555427 — cell biology — Posted on 2023-08-30
232 PanKmer: k-mer based and reference-free pangenome analysis
Aylward, A. J.; Petrus, S.; Mamerto, A.; Hartwick, N. T.; Michael, T. P.
10.1101/2023.03.31.535143 — bioinformatics — Posted on 2023-08-30
233 Spatial enhancer activation determines inhibitory neuron identity
Dvoretskova, E.; Ho, M. C.; Kittke, V.; Neuhaus, F.; Vitali, I.; Lam, D. D.; Delgado, I.; Feng, C.; Torres, M.; Winkelmann, J.; Mayer, C.
10.1101/2023.01.30.525356 — developmental biology — Posted on 2023-08-30
236 Event-related modulation of alpha rhythm explains the auditory P300 evoked response in EEG
Studenova, A. A.; Forster, C.; Engemann, D. A.; Hensch, T.; Sander, C.; Mauche, N.; Hegerl, U.; Loeffler, M.; Villringer, A.; Nikulin, V. V.
10.1101/2023.02.20.529191 — neuroscience — Posted on 2023-08-30
237 High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target
Cid, L. L.; Leong, J. K.; Botana, I. F.; Paul, Y.; Wierz, M.; Floerchinger, A.; Gonder, S.; Pagano, G.; Chazotte, M.; Bestak, K.; Schifflers, C.; Iskar, M.; Roider, T.; Czernilofsky, F.; Bruch, P.-M.; Mallm, J.-P.; Cosma, A.; Campton, D. E.; Gerhard-Hartmann, E.; Rosenwald, A.; Colomer, D.; Campo, E.; Shapiro, D.; Dietrich, S.; Lichter, P.; Moussay, E.; Paggetti, J.; Zapatka, M.; Seiffert, M.
10.1101/2022.12.15.519719 — cancer biology — Posted on 2023-08-30
240 An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin.
Hill, J. A.; Nyathi, Y. R.; Horrell, S.; von Stetten, D.; Axford, D.; Owen, R. L.; Beddard, G. S.; Pearson, A. R.; Ginn, H. M.; Yorke, B. A.
10.1101/2023.08.25.554810 — biochemistry — Posted on 2023-08-30
241 The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase
Forsberg, Z.; Stepnov, A.; Tesei, G.; Wang, Y.; Buchinger, E.; Kristiansen, S. K.; Aachmann, F. L.; Arleth, L.; Eijsink, V. G. H.; Lindorff-Larsen, K.; Courtade, G.
10.1101/2023.06.01.543078 — biochemistry — Posted on 2023-08-30
245 An amphipathic helix facilitates direct membrane binding of Mycoplasma FtsZ
Dutta, S.; Poddar, S. M.; Chakraborty, J.; Srinivasan, R.; Gayathri, P.
10.1101/2023.08.29.555414 — microbiology — Posted on 2023-08-30
246 PyHFO: Lightweight Deep Learning-poweredEnd-to-End High-Frequency Oscillations AnalysisApplication
Zhang, Y.; Liu, L.; Ding, Y.; Chen, X.; Monsoor, T.; Daida, A.; Oana, S.; Hussain, S. A.; Sankar, R.; Fallah, A.; Engel, J.; Staba, R. J.; Speier, W.; Zhang, J.; Nariai, H.; Roychowdhury, V.
10.1101/2023.08.25.554741 — neuroscience — Posted on 2023-08-30
247 A hybrid combination of in vitro cultured buccal mucosal cells using two different methodologies, complementing each other in successfully repairing a stricture-inflicted human male urethral epithelium
Horiguchi, A.; Kushibiki, T.; Yoshine, M.; Shinchi, M.; Ojima, K.; Hirano, Y.; Katoh, S.; Iwasaki, M.; Surya Prakash, V.; Ichiyama, K.; Senthilkumar, R.; Preethy, S.; Abraham, S. J.
10.1101/2023.08.29.555240 — synthetic biology — Posted on 2023-08-30
249 Intermittent fasting promotes ILC3s secreting IL-22 contributing to the beigeing of white adipose tissue
Zhang, W.; Yin, Y.; Chen, H.; Sun, L.; Feng, L.; Han, X.; Zhang, Y.; Zhai, W.; Zhang, Z.; Mulholland, M.
10.1101/2023.08.29.555436 — physiology — Posted on 2023-08-30
250 Step-wise activation of a Family C GPCR
Kumar, K. K.; Wang, H.; Habrian, C.; Latorraca, N. R.; Xu, J.; O'Brien, E. S.; Zhang, C.; Montabana, E.; Koehl, A.; Marqusee, S.; Isacoff, E. Y.; Kobilka, B. K.
10.1101/2023.08.29.555158 — biophysics — Posted on 2023-08-30
253 A defined diet for pre-adult Drosophila melanogaster
Martelli, F.; Quig, A.; Mele, S.; Lin, J.; Fulton, T. L.; Wansbrough, M.; Barlow, C. K.; Schittenhelm, R. B.; Johnson, T. K.; Piper, M. D.
10.1101/2023.08.28.555220 — genetics — Posted on 2023-08-30
264 Mutation in SLC45A2 leads to loss of melanin in parrot feathers
Ghosh Roy, S.; Abdu, M.; Bakhrat, A.; Afonso, S.; Pereira, P.; Carneiro, M.; Abdu, U.
10.1101/2023.08.29.555428 — developmental biology — Posted on 2023-08-30
265 Ebola Virus Sequesters IRF3 in Viral Inclusion Bodies to Evade Host Antiviral Immunity
Zhu, L.; Jin, J.; Wang, T.; Hu, Y.; Liu, H.; Gao, T.; Dong, Q.; Jin, Y.; Li, P.; Liu, Z.; Huang, Y.; Liu, X.; Cao, C.
10.1101/2023.04.20.537734 — microbiology — Posted on 2023-08-30
267 Shifting Redox Reaction Equilibria on Demand Using an Orthogonal Redox Cofactor
Aspacio, D.; Zhang, Y.; Cui, Y.; King, E.; Black, W. B.; Perea, S.; Luu, E.; Siegel, J. B.; Li, H.
10.1101/2023.08.29.555398 — synthetic biology — Posted on 2023-08-30
268 CRISPR-Hybrid: A CRISPR-Mediated Intracellular Directed Evolution Platform for RNA Aptamers
Su-Tobon, Q.; Fan, J.; Feeney, K.; Ren, H.; Autissier, P.; Wang, P.; Huang, Y.; Niu, J.
10.1101/2023.08.29.555185 — synthetic biology — Posted on 2023-08-30
269 Jet injection potentiates naked mRNA SARS-CoV-2 vaccine in mice and non-human primates by adding physical stress to the skin
Abbasi, S.; Matsui-Masai, M.; Yasui, F.; Hayashi, A.; Tockary, T.; Akinaga, S.; Kohara, M.; Kataoka, K.; Uchida, S.
10.1101/2023.02.27.530188 — bioengineering — Posted on 2023-08-30
272 FLAgellum Member 8 modulates extravascular distribution of African trypanosomes.
Calvo Alvarez, E.; Ngoune, J. M. T.; Sharma, P.; Cooper, A.; Camara, A.; Travaille, C.; Crouzols, A.; MacLeod, A.; Rotureau, B.
10.1101/2023.02.20.529185 — microbiology — Posted on 2023-08-30
273 PanKmer: k-mer based and reference-free pangenome analysis
Aylward, A. J.; Petrus, S.; Mamerto, A.; Hartwick, N. T.; Michael, T. P.
10.1101/2023.03.31.535143 — bioinformatics — Posted on 2023-08-29
275 Identification of human skin microbiome odorants that manipulate mosquito landing behavior
Coutinho-Abreu, I. V.; Jamshidi, O.; Raban, R.; Atabakhsh, K.; Merriman, J. A.; Fischbach, M. A.; Akbari, O. S.
10.1101/2023.08.19.553996 — zoology — Posted on 2023-08-29
277 Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
Chang, C.; Banerjee, S. L.; Park, S. S.; Zhang, X.; Cotnoir-White, D.; Desbois, M.; Grill, B.; Kania, A.
10.1101/2023.06.12.544638 — cell biology — Posted on 2023-08-29
282 Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females
Babey, M. E.; Krause, W. C.; Herber, C. B.; Chen, K.; Nikkannen, J.; Rodriquez, R.; Zhang, X.; Castro-Navarro, F.; Wang, Y.; Villeda, S.; Lane, N. E.; Scheller, E. L.; Chan, C. K. F.; Ambrosi, T. H.; Ingraham, H. A.
10.1101/2023.08.28.554707 — neuroscience — Posted on 2023-08-29
283 Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia
Zhu, B.; Ainsworth, R. I.; Wang, Z.; Liu, Z.; Sierra, S.; Deng, C.; Callado, L. F.; Meana, J. J.; Wang, W.; Lu, C.; Gonzalez-Maeso, J.
10.1101/2021.07.14.452426 — neuroscience — Posted on 2023-08-29
284 Angiogenic Steroids Induce Pathologic Scarring in a Preclinical Swine Model Via Dysfunctional Extracellular Matrix Deposition.
Reiche, E.; Keller, P. R.; Soares, V.; Schuster, C. R.; Billaud, M.; Rahmayanti, S.; Hu, S.; Hoover-Watson, H.; Mroueh, J.; Mroueh, V.; Tan, Y.; Kim, S. Y.; Newell-Fugate, A. E.; Lian, C. G.; Coon, D.
10.1101/2023.05.29.542765 — systems biology — Posted on 2023-08-29
289 Molecular Mechanism of PP2A/B55α Inhibition by IER5
Cao, R.; Jones, D. T.; Pan, L.; Wang, S.; Rawson, S.; Aster, J. C.; Blacklow, S. C.
10.1101/2023.08.29.555174 — biochemistry — Posted on 2023-08-29
291 Comparative metabolomics and microbiome analysis of Ethanol vs. OMNImet/gene GUT fecal stabilization
Isokaanta, H.; Pinto da Silva, L.; Karu, N.; Kallonen, T.; Aatsinki, A. K.; Hankemeier, T.; Schimmel, L.; Diaz, E.; Hyotylainen, T.; Dorrestein, P. C.; Knight, R.; Oresic, M.; Daouk, R. K.; Dickens, A. M.; Lamichhane, S.
10.1101/2023.08.29.555241 — biochemistry — Posted on 2023-08-29
292 Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling.
Choi, A. S.; Jenkins-Lane, L. M.; Barton, W.; Kumari, A.; Lancaster, C.; Raulerson, C.; Ji, H.; Altomare, D.; Starr, M. D.; Whitaker, R.; Phaeton, R.; Arend, R. C.; Shtutman, M.; Nixon, A. B.; Hempel, N.; Lee, N. Y.; Mythreye, K.
10.1101/2023.08.29.555364 — biochemistry — Posted on 2023-08-29
295 Estimating the number of breeders from helminth larvae with genomic data.
Dennis, T. P. W.; Sands, W.; Opoku, M.; Debrah, A.; Debrah, L. B.; Pfarr, K.; Klarmann-Schulz, U.; Hoerauf, A.; Specht, S.; Scandale, I.; Ranford-Cartwright, L. C.; Lamberton, P. H. L.
10.1101/2023.08.25.554821 — genomics — Posted on 2023-08-29
297 Environmental filtering of life-history trait diversity in urban populations of Arabidopsis thaliana
Schmitz, G.; Linstaedter, A.; Frank, A. S.; Dittberner, H.; Thome, J.; Schrader, A.; Linne von Berg, K.-H.; Fulgione, A.; Coupland, G.; de Meaux, J.
10.1101/2022.10.03.510679 — evolutionary biology — Posted on 2023-08-29
299 Bird communities in a selectively logged tropical montane forest are dominated by small, low-elevation species
Chanda, R.; Rai, S.; Tamang, B.; Munda, B.; Pradhan, D.; Rai, M.; Biswakarma, A.; Srinivasan, U.
10.1101/2023.04.15.537021 — ecology — Posted on 2023-08-29
300 Delayed postglacial colonization of Betula in Iceland and the circum North Atlantic
Harning, D. J.; Sacco, S.; Anamthawat-Jonsson, K.; Ardenghi, N.; Thordarson, T.; Raberg, J.; Sepulveda, J.; Geirsdottir, A.; Shapiro, B.; Miller, G. H.
10.1101/2023.03.13.532414 — ecology — Posted on 2023-08-29
304 Control of microtubules in neuronal processes by profilin 1 and actomyosin
Cisterna, B. A.; Skruber, K.; Jane, M. L.; Camesi, C. I.; Nguyen, I. D.; Warp, P. V.; Black, J. B.; Butler, M. T.; Bear, J. E.; Read, T.-A.; Vitriol, E. A.
10.1101/2023.08.25.554891 — cell biology — Posted on 2023-08-29
306 Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
Chan, A. W.; Broncel, M.; Yifrach, E.; Haseley, N. R.; Chakladar, S.; Andree, E.; Herneisen, A. L.; Shortt, E.; Treeck, M.; Lourido, S.
10.1101/2023.01.11.523553 — microbiology — Posted on 2023-08-29
308 Atypical memory B cells form a pre-plasmacellular reservoir for steady-state IgD responses to common nasopharyngeal antigens
Tacho-Pinot, R.; Bashour, H.; Filipska, M.; Tejedor-Vaquero, S.; de Campos-Mata, L.; Saez-Gordon, A.; Perera-Bel, J.; Guzman, M.; Marcos-Fa, X.; Canales-Herrerias, P.; Dominguez-Barragan, J.; Arcos-Ribas, B.; Slabodkin, A.; Chernigovskaya, M.; de la Concepcion, M. L. R.; Gutierrez-Marcos, J.; Garcia-Garcia, A.; Nascimento-Osorio, A.; Pascal, M.; Alsina, L.; Arostegui, J. I.; Mehandru, S.; Cunningham-Rundles, C.; Carrillo, J.; Magri, G.; Greiff, V.; Cerutti, A.
10.1101/2023.08.29.554748 — immunology — Posted on 2023-08-29
310 Inhibitory temporo-parietal effective connectivity is associated with explicit memory performance in older adults
Schott, B. H.; Soch, J.; Kizilirmak, J. M.; Schütze, H.; Assmann, A.; Maass, A.; Ziegler, G.; Sauvage, M.; Richter, A.
10.1101/2022.12.22.521668 — neuroscience — Posted on 2023-08-29
313 An in vitro neurogenetics platform for precision disease modeling in the mouse
CORTES, D. E.; ESCUDERO, M.; MITRA, A.; KORGAN, A. C.; EDWARDS, A.; Aydin, S. C.; Munger, S. C.; O'CONNELL, K. M. S.; Reinholdt, L. G.; PERA, M. F.
10.1101/2022.01.21.477242 — neuroscience — Posted on 2023-08-29
315 Face-Selective Responses in FFA and MPFC Emerge Early in Human Infancy
Kosakowski, H. L.; Cohen, M. A.; Herrera, L.; Nichoson, I.; Kanwisher, N. G.; Saxe, R.
10.1101/2021.12.04.471085 — neuroscience — Posted on 2023-08-29
318 Histone mark age of human tissues and cells
de Lima Camillo, L. P.; Asif, M. H.; Horvath, S.; Larschan, E.; Singh, R.
10.1101/2023.08.21.554165 — systems biology — Posted on 2023-08-29
320 Energetics of the Microsporidian Polar Tube Invasion Machinery
Chang, R.; Davydov, A.; Jaroenlak, P.; Budaitis, B.; Ekiert, D. C.; Bhabha, G.; Prakash, M.
10.1101/2023.01.17.524456 — biophysics — Posted on 2023-08-29
321 ASTK: a machine learning-based integrative software for alternative splicing analysis
Huang, S.; He, J.; Yu, L.; Guo, J.; Jiang, S.; Sun, Z.; Cheng, L.; Chen, X.; Ji, X.; Zhang, Y.
10.1101/2023.01.03.522470 — bioinformatics — Posted on 2023-08-29
322 Benchmarking informatics approaches for virus discovery: Caution is needed when combining in silico identification methods
Hegarty, B.; Riddell, J.; Bastien, G. E.; Langenfeld, K.; Lindback, M.; Saini, J. S.; Wing, A.; Zhang, J.; Duhaime, M.
10.1101/2023.08.07.552334 — bioinformatics — Posted on 2023-08-29
324 Protein Coronas on Functionalized Nanoparticles Enable Quantitative and Precise Large-Scale Deep Plasma Proteomics
Huang, T.; Wang, J.; Stukalov, A.; Donovan, M. K. R.; Ferdosi, S.; Williamson, L.; Just, S.; Castro, G.; Cantrell, L. S.; Elgierari, E.; Benz, R. W.; Huang, Y.; Motamedchaboki, K.; Hakimi, A.; Arrey, T.; Damoc, E.; Kreimer, S.; Farokhzad, O. C.; Batzoglou, S.; Siddiqui, A.; Van Eyk, J. E.; Hornburg, D.
10.1101/2023.08.28.555225 — biochemistry — Posted on 2023-08-29
325 Oxidative regulation of TDP-43 self-association by a beta-to-alpha conformational switch
Gu, J.; Zhou, X.; Sutherland, L.; Kato, M.; Jaczynska, K.; Rizo, J.; McKnight, S.
10.1101/2023.08.29.555361 — biochemistry — Posted on 2023-08-29
327 PTPN2 copper-sensing rapidly relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression
Ross, M. O.; Xie, Y.; Owyang, R. C.; Ye, C.; Zbihley, O. N. P.; Lyu, R.; Wu, T.; Wang, P.; Karginova, O.; Olopade, O. I.; Zhao, M.; He, C.
10.1101/2023.08.29.555401 — biochemistry — Posted on 2023-08-29
329 Uncovering the molecular signatures of russet skin formation in Niagara grapevine (Vitis vinifera x Vitis labrusca)
Niederauer, G. F.; de Oliveira, G. L.; Aono, A. H.; Graciano, D. d. S.; Guerreiro, S. M. C.; Moura, M. F.; de Souza, A. P.
10.1101/2023.08.25.554330 — genetics — Posted on 2023-08-29
330 Insights into Digit Evolution from a Fate Map Study of the Forearm
Oh, J. D. H.; Saunders, D. D. Z.; McTeir, L.; Jackson, M.; Glover, J. D.; Schoenebeck, J. J.; Lettice, L. A.; Davey, M. G.
10.1101/2023.08.29.555165 — developmental biology — Posted on 2023-08-29
331 ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims
Lewis, T. R.; Makia, M. S.; Castillo, C. M.; Hao, Y.; Al-Ubaidi, M. R.; Skiba, N. P.; Conley, S. M.; Arshavsky, V. Y.; Naash, M. I.
10.1101/2023.07.02.547380 — cell biology — Posted on 2023-08-29
333 HIV-1 binds dynein directly to hijack microtubule transport machinery
Badieyan, S.; Lichon, D.; Andreas, M. P.; Gillies, J. P.; Peng, W.; Shi, J.; DeSantis, M. E.; Aiken, C. R.; Böcking, T.; Giessen, T. W.; Campbell, E. M.; Cianfrocco, M. A.
10.1101/2023.08.29.555335 — microbiology — Posted on 2023-08-29
334 Madariaga and Venezuelan equine encephalitis virus seroprevalence in rodent enzootic hosts in Eastern and Western Panama
Carrera, J. P.; Galue, J.; de Souza, W. M.; Lezcano-Coba, C. A.; Torres-Cosme, R.; Cumbrera, A.; Vasilakis, N.; Tesh, R. B.; Guzman, H.; Weaver, S.; Vittor, A. Y.; Samudio, R.; Pascale, J. M.; Valderrama, A.; Caceres-Carrera, L.; Donnelly, C. A.; Faria, N. R.
10.1101/2023.08.28.555226 — microbiology — Posted on 2023-08-29
335 Population genomic analyses reveal extensive genomic regions within selective sweeps associated with adaptation and demographic history of a wheat fungal pathogen
Xia, C.; Xia, C.; Huang, L.; Zhao, N.; Li, H.; Zhang, X.; Qiu, A.; Tang, W.; Wang, M.; Chen, X.; Liu, B.; Zhang, H.; Gao, L.; Chen, W.; Liu, T.
10.1101/2023.08.29.555254 — microbiology — Posted on 2023-08-29
338 A deep genetic analysis of banana Fusarium wilt pathogens of Cuba in a Latin American and Caribbean diversity landscape
de la Parte, E. M.; Vicente, L. P.; Torres, D. E.; van Westerhoven, A. C.; Meijer, H. J. G.; Seidl, M. F.; Kema, G. H.
10.1101/2023.08.29.553192 — microbiology — Posted on 2023-08-29
339 Phylogeny and disease links of a widespread and ancient gut phage lineage
de Jonge, P. A.; van den Born, B.-J. H.; Zwinderman, A. H.; Nieuwdorp, M.; Dutilh, B. E.; Herrema, H.
10.1101/2023.08.29.555303 — microbiology — Posted on 2023-08-29
340 A mutant fitness compendium in Bifidobacteria reveals molecular determinants of colonization and host-microbe interactions
Shiver, A. L.; Sun, J.; Culver, R.; Violette, A.; Wynter, C.; Nieckarz, M.; Mattiello, S. P.; Sekhon, P. K.; Friess, L.; Carlson, H. K.; Wong, D.; Higginbottom, S. K.; Weglarz, M.; Wang, W.; Knapp, B. D.; Guiberson, E.; Sanchez, J.; Huang, P.-H.; Garcia, P. A.; Buie, C. R.; Good, B. H.; DeFelice, B.; Cava, F.; Scaria, J.; Sonnenburg, J.; Van Sinderen, D.; Deutschbauer, A. M.; Huang, K. C.
10.1101/2023.08.29.555234 — microbiology — Posted on 2023-08-29
341 Vestibular CCK neurons drive motion-induced malaise
Machuca-Marquez, P.; Sanchez-Benito, L.; Menardy, F.; Urpi, A.; Girona, M.; Puighermanal, E.; Appiah, I.; Palmiter, R.; Sanz, E.; Quintana, A.
10.1101/2021.09.08.459510 — neuroscience — Posted on 2023-08-29
342 Kras loss of heterozygosity promotes MAPK dependent pancreatic ductal adenocarcinoma and induces therapeutic sensitivity
Fey, S. K.; Najumudeen, A. K.; Ford, C. A.; Gilroy, K.; Upstill-Goddard, R.; Clark, W.; Nixon, C.; Chang, D. K.; Barry, S. T.; Morton, J. P.; Campbell, A. D.; Sansom, O. J.
10.1101/2023.08.29.552598 — cancer biology — Posted on 2023-08-29
343 Modeling fragment counts improves single-cell ATAC-seq analysis
Martens, L. D.; Yepez, V. A.; Fischer, D. S.; Theis, F. J.; Gagneur, J.
10.1101/2022.05.04.490536 — bioinformatics — Posted on 2023-08-29
344 DeepRTAlign: toward accurate retention time alignment for large cohort mass spectrometry data analysis
Liu, Y.; Yang, Y.; Chen, W.; Shen, F.; Xie, L.; Zhang, Y.; Zhai, Y.; He, F.; Zhu, Y.; Chang, C.
10.1101/2022.12.24.521877 — bioinformatics — Posted on 2023-08-29
345 TESOGENASE, An Engineered Nuclease Editor for Enhanced Targeted Genome Integration
Nam, H.; Xie, K.; Majumdar, I.; Yang, S.; Starzyk, J.; Lee, D.; Shan, R.; Li, J.; Wu, H.
10.1101/2023.08.28.553855 — bioengineering — Posted on 2023-08-29
346 Discovery of 2-amide-3-methylester thiophenes inhibiting SARS-CoV-2 ADP-ribosyl hydrolysing macrodomain and coronavirus replication
Wazir, S.; Parviainen, T. A. O.; Maksimainen, M. M.; Duong, M. T. H.; Pfannenstiel, J. J.; Cluff, D.; Sowa, S. T.; Galera-Prat, A.; Ferraris, D. V.; Fehr, A.; Heiskanen, J. P.; Lehtiö, L.
10.1101/2023.08.28.555062 — biochemistry — Posted on 2023-08-29
348 High-efficiency gene editing in Anopheles sinensis using ReMOT control
Yang, X.; Ling, X.; Sun, Q.; Qiu, P.; Xiang, K.; Hong, J.; He, S.; Chen, J.; Ding, X.; Hu, H.; He, Z.; Chen, B.; Zhou, C.; Qiao, L.
10.1101/2023.08.29.555096 — genetics — Posted on 2023-08-29
352 Age-Associated Weaker Immunity to Coronaviruses is Characteristic of Children that Develop Multisystem Inflammatory Syndrome following SARS-CoV-2 Infection
Camerini, D.; Arrieta, A.; Randall, A.; Gach, J.; Maecker, H.; Hoang, J.; Imfeld, K.; Osborne, S.; Enriquez, C.; Hung, C.; Edgar, J.; Shandling, A. D.; Huynh, V.; Teng, A.; Pablo, J.; Forthal, D.; Campo, J. J.; Nugent, D.
10.1101/2023.08.28.555120 — immunology — Posted on 2023-08-29
355 A systems vaccinology resource to develop and test computational models of immunity
Shinde, P.; Soldevila, F.; Reyna, J.; Aoki, M.; Rasmussen, M.; Willemsen, L.; Kojima, M.; Ha, B.; Greenbaum, J. A.; Overton, J. A.; Guzman-Orozco, H.; Nili, S.; Orfield, S.; Gygi, J. P.; Antunes, R. d. S.; Sette, A.; Grant, B. J.; Olsen, L. R.; Konstorum, A.; Guan, L.; Ay, F.; Kleinstein, S. H.; Peters, B.
10.1101/2023.08.28.555193 — systems biology — Posted on 2023-08-29
361 CD8 T-cell dysfunction is linked with CAR T-cell failure and can be mitigated by a non-alpha IL-2 agonist, pegenzileukin
Reville, P. K.; Sheikh, I. N.; Choi, A.; Dai, E.; Henderson, J.; Li, X.; Rojas, E.; Le, C. C.; Okwuchi, C.; Devonish, M.; Carrio, R.; Pate, N.; Malley, K.; Bangari, D.; Givigan, J.-A.; Shi, C.; Liu, B.; Byers, T.; Westin, J.; Ahmed, S.; Fowler, N.; Fayad, L.; Lee, H. J.; Nastoupil, L.; Sassoon, I.; Cucchetti, M.; Wang, R.; Agarwal, M.; Abbadessa, G.; Meng, R.; Meibalan, E.; Powers, L.; Cao, J.; Ying, X.; Balko, K.; Yu, Q.; Jiao, J.; Cortez-Retamozo, V.; Sidhu, S.; Shaffer, D.; Neelapu, S.; Wang, L.; Li, X.; Green, M. R.
10.1101/2023.08.28.555127 — immunology — Posted on 2023-08-29
362 HDAC6 inhibition as a mechanism to prevent axon degeneration in the mSOD1G93A mouse model of ALS.
Phipps, A. J.; Dwyer, S.; Collins, J. M.; Kabir, F.; Atkinson, R. A.; Chowdhury, M. A.; Matthews, L.; Dixit, D.; Terry, R. S.; Smith, J.; Gueven, N.; Bennett, W.; Cook, A. L.; King, A. E.; Perry, S.
10.1101/2023.08.28.555025 — neuroscience — Posted on 2023-08-29
363 Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth
Fattori, V.; Zaninelli, T. H.; Rasquel-Oliveira, F. S.; Heintz, O. K.; Jain, A.; Sun, L.; Seshan, M. L.; Peterse, D.; Lindholm, A. E.; Anchan, R. M.; Verri, W. A.; Rogers, M. S.
10.1101/2023.08.28.555101 — neuroscience — Posted on 2023-08-29
365 Ketogenic diet alters microglial morphology and changes the hippocampal lipidomic profile distinctively in stress susceptible versus resistant male mice upon repeated social defeat
Ibanez, F. G.; Halvorson, T.; Sharma, K.; McKee, C.; Carrier, M.; Picard, K.; Vernoux, N.; Bisht, K.; Deslauriers, J.; Lalowski, M.; Tremblay, M.-E.
10.1101/2023.08.28.555135 — neuroscience — Posted on 2023-08-29
366 A viral vector model for circuit-specific synucleinopathy
Lantheaume, A.; Schoeneberg, N.; Rodriguez-Rozada, S.; Doll, D.; Schellenberger, M.; Kobel, K.; Katzenberger, K.; Signoret-Genest, J.; Tissone, A. I.; Ip, C. W.; Esposito, M. S.; Tovote, P.
10.1101/2023.08.28.555129 — neuroscience — Posted on 2023-08-29
367 PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination
Gharibani, P.; Abramson, E.; Shanmukha, S.; Smith, M. D.; Godfrey, W. H.; Lee, J. J.; Hu, J.; Baydyuk, M.; Dorion, M.-F.; Deng, X.; Guo, Y.; Hwang, S.; Huang, J. K.; Calabresi, P. A.; Kornberg, M. D.; Kim, P. M.
10.1101/2023.08.28.555084 — neuroscience — Posted on 2023-08-29
368 Neuronal apoE4 induces early hyperexcitability in select populations of hippocampal neurons by altering Nell2 expression
Jang, S.-S.; Tabuena, D. R.; Grone, B.; Yip, O.; Blumenfeld, J.; Koutsodendris, N.; Ding, L.; Xu, Q.; Yoon, S. Y.; Huang, Y.; Zilberter, M.
10.1101/2023.08.28.555153 — neuroscience — Posted on 2023-08-29
374 Methods for evaluating unsupervised vector representations of genomic regions
Zheng, G.; Rymuza, J.; Gharavi, E.; LeRoy, N. J.; Zhang, A.; Sheffield, N. C.
10.1101/2023.08.28.555137 — bioinformatics — Posted on 2023-08-29
375 Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
Currie, M.; Davies, J.; Scalise, M.; Gulati, A.; Wright, J.; Newton-Vesty, M.; Abeysekera, G.; Subramanian, R.; Wahlgren, W.; Friemann, R.; Allison, J.; Mace, P.; Griffin, M.; Demeler, B.; Wakatsuki, S.; Drew, D.; Indiveri, C.; Dobson, R.; North, R.
10.1101/2023.08.28.549404 — biochemistry — Posted on 2023-08-29
376 Behavioural, physiological, and genetic drivers of coping
Bhattacharjee, D.; Guojonsdottir, A. R.; Escriche Chova, P.; Middelburg, E.; Jackels, J.; de Groot, N. G.; Wallner, B.; Massen, J. J. M.; Pfluger, L. S.
10.1101/2023.08.28.555090 — animal behavior and cognition — Posted on 2023-08-29
377 Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic adaptation to malnutrition in Drosophila
Cavigliasso, F.; Savitskiy, M.; Koval, A.; Erkosar, B.; Savary, L.; Gallart-Ayala, H.; Ivanisevic, J.; Katanaev, V. L.; Kawecki, T. J.
10.1101/2023.08.28.555138 — evolutionary biology — Posted on 2023-08-29
379 The genomic landscape, causes, and consequences of extensive phylogenomic discordance in Old World mice and rats
Thomas, G. W. C.; Hughes, J. J.; Kumon, T.; Berv, J. S.; Nordgren, C. E.; Lampson, M.; Levine, M.; Searle, J. B.; Good, J. M.
10.1101/2023.08.28.555178 — evolutionary biology — Posted on 2023-08-29
381 Environmental circadian disruption re-programs liver circadian gene expression
Duong, H. A.; Baba, K.; DeBruyne, J.; Davidson, A. J.; Ehlen, J. C.; Powell, M. D.; Tosini, G.
10.1101/2023.08.28.555175 — molecular biology — Posted on 2023-08-29
383 The adaptive immune response to Trichuris in wild versus laboratory mice: An established model system in context
Mair, I.; Fenn, J.; Wolfenden, A.; Lowe, A.; Bennett, A.; Muir, A.; Thompson, J.; Dieumerci, O.; Logunova, L.; Shultz, S.; Else, K. J.; Bradley, J. E.
10.1101/2023.08.28.555155 — immunology — Posted on 2023-08-29
384 Lesion aware automated processing pipeline for multimodal neuroimaging stroke data and The Virtual Brain (TVB)
Bey, P.; Dhindsa, K.; Kashyap, A.; Schirner, M.; Feldheim, J.; Bönstrup, M.; Schulz, R.; Cheng, B.; Thomalla, G.; Gerloff, C.; Ritter, P.
10.1101/2023.08.28.555078 — neuroscience — Posted on 2023-08-29
387 Dysregulated actin dynamics and cofilin correlate with TDP-43 pathology in sporadic amyotrophic lateral sclerosis
Jagaraj, C. J.; Mehta, P.; Parakh, S.; Shadfar, S.; Jamalli, M. S.; Suchowerska, A. K.; Ragagnin, A.; Vidal, M.; Sultana, J.; Fath, T.; Atkin, J.
10.1101/2023.08.28.555209 — neuroscience — Posted on 2023-08-29
392 Epigenome-wide profiling in the dorsal raphe nucleus highlights cell-type-specific changes in TNXB in Alzheimer's disease
Riemens, R. J. M.; Pishva, E.; Iatrou, A.; Roubroeks, J. A. Y.; Nolz, J.; Lardenoije, R.; Ali, M.; del Sol Mesa, A.; Delgado-Morales, R.; Esteller, M.; Kenis, G.; Rutten, B. P. F.; Lesch, K.-P.; Ginsberg, S. D.; Coleman, P.; Mill, J.; Mastroeni, D.; Ramirez, A.; Haaf, T.; Lunnon, K.; van den Hove, D. L. A.
10.1101/2023.08.28.555168 — neuroscience — Posted on 2023-08-29
395 Mechano-signaling of prostate tumor initiating cells facilitates their tropism to stiff metastatic niche
Chen, L.; Zhao, G.; De Menna, M.; Coppola, S.; Groenewoud, A.; Landman, N.; Schieven, S.; Thalmann, G. N.; Schmidt, T.; de Vrie, J.; Kruithof-de Julio, M.; Snaar, E. B.
10.1101/2023.08.28.553410 — cancer biology — Posted on 2023-08-29
396 Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation
Broggini, L.; Barzago, M.; Speranzini, V.; Schulte, T.; Sonzini, F.; Giono, M.; Romeo, M.; Milani, P.; Caminito, S.; Mazzini, G.; Rognoni, P.; Merlini, G.; Pappone, C.; Anastasia, L.; Nuvolone, M.; Palladini, G.; Diomede, L.; Ricagno, S.
10.1101/2023.08.28.555063 — biophysics — Posted on 2023-08-29
403 Non-invasive measurement of intra-tumoral fluid dynamics with localized convolutional function regression
Woodall, R. T.; Esparza, C. C.; Gutova, M.; Wang, M.; Cunningham-Reynolds, J.; Brummer, A. B.; Stine, C.; Brown, C.; Munson, J. M.; Rockne, R. C.
10.1101/2023.08.28.554919 — bioengineering — Posted on 2023-08-29
405 3D Printed Ti3C2Tx MXene/PCL Scaffolds for Guided Neuronal Growth and Photothermal Stimulation
Li, J.; Hashemi, P.; Liu, T.; Dang, K. M.; Brunk, M. G. K.; Mu, X.; Nia, A. S.; Sacher, W. D.; Feng, X.; Poon, J. K. S.
10.1101/2023.08.28.555002 — bioengineering — Posted on 2023-08-29
406 Pigment Binding in The Light-Dependent Protochlorophyllide Oxidoreductase
Pesara, P.; Szafran, K.; Nguyen, H. C.; Sirohiwal, A.; Pantazis, D. A.; Gabruk, M.
10.1101/2023.08.28.555081 — biochemistry — Posted on 2023-08-29
411 Ancient farmer and steppe pastoralist-related founding lineages contributed to the complex landscape of episodes in the diversification of Chinese paternal lineages
Wang, M.; Huang, Y.; Liu, K.; Yuan, H.; Duan, S.; Wang, Z.; Wei, L.; Yao, H.; Sun, Q.; Zhong, J.; Tang, R.; Chen, J.; Sun, Y.; Li, X.; Su, H.; Yang, Q.; Hu, L.; Yun, L.; Yang, J.; Nie, S.; Cai, Y.; Yan, J.; Zhou, K.; 10K_CPGDP Consortium, ; Wang, C.-C.; Zhu, B.; Liu, C.; He, G.
10.1101/2023.08.28.555114 — genetics — Posted on 2023-08-29
412 Absence of chromosome axis proteins recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri
Legrand, S.; Saifudeen, A.; Bordelet, H.; Vernerey, J.; Guille, A.; Bignaut, A.; Thierry, A.; Acquaviva, L.; Gaudin, M.; Sanchez, A.; Johnson, D.; Friedrcih, A.; Schacherer, J.; Neale, M.; Borde, V.; Koszul, R.; llorente, b.
10.1101/2023.08.28.555118 — genetics — Posted on 2023-08-29
413 Ribose lowers RpoS translation through RbsD mRNA
Peterson, C. N.; Badaoui, A.; Smith, I.; Balla, M.; Cavanaugh, M.; Lockart, J.; Parsons, D.; Marte, E.; Dorean, S.; Diop, C.; Tran, T.
10.1101/2023.08.28.555190 — genetics — Posted on 2023-08-29
416 Intermodal consistency of whole-brain connectivity and signal propagation delays
Jedynak, M.; Troisi Lopez, E.; Romano, A.; Jirsa, V.; David, O.; Sorrentino, P.
10.1101/2023.08.28.555074 — neuroscience — Posted on 2023-08-29
417 Developmental pyrethroid exposure disrupts molecular pathways for circadian rhythms and synaptic plasticity in mouse brain.
Nguyen, J. H.; Curtis, M. A.; Imami, A. S.; Ryan, W. G.; Alganem, K.; Neifer, K. L.; Nawor, C. N.; Kistler, B. P.; Miller, G. W.; Shukla, R.; McCullumsmith, R. E.; Burkett, J. P.
10.1101/2023.08.28.555113 — neuroscience — Posted on 2023-08-29
418 PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport
Tziortzouda, P.; Steyaert, J.; Scheveneels, W.; Sicart, A.; Stoklund Dittlau, K.; Barbosa Correia, A. M.; Pal, A.; Hermann, A.; Van Damme, P.; Moens, T.; Van Den Bosch, L.
10.1101/2023.08.28.555106 — neuroscience — Posted on 2023-08-29
419 A subclass of evening cells promotes the switch from arousal to sleep at dusk
Brown, M. P.; Verma, S.; Palmer, I.; Zuniga, A. G.; Rosensweig, C.; Keles, M. F.; Wu, M. N.
10.1101/2023.08.28.555147 — neuroscience — Posted on 2023-08-29
420 A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion
Montaner, M.; Denom, J.; Simon, V.; Jiang, W.; Holt, M. K.; Brierley, D.; Rouch, C.; Foppen, E.; Kassis, N.; Jarriault, D.; Khan, D.; Eygret, L.; Mifsud, F.; Hodson, D. J.; Broichhagen, J.; Van Oudenhove, L.; Fioramonti, X.; Gault, V.; Cota, D.; Reimann, F.; Gribble, F. M.; Migrenne-Li, S.; Trapp, S.; Gurden, H.; Magnan, C.
10.1101/2023.08.28.555086 — physiology — Posted on 2023-08-29
421 Reply to: Contribution of carbon inputs to soil carbon accumulation cannot be neglected
Tao, F.; Houlton, B. Z.; Frey, S. D.; Lehmann, J.; Manzoni, S.; Huang, Y.; Jiang, L.; Mishra, U.; Hungate, B. A.; Schmidt, M. W. I.; Reichstein, M.; Carvalhais, N.; Ciais, P.; Wang, Y.-P.; Ahrens, B.; Hugelius, G.; Hocking, T. D.; Lu, X.; Shi, Z.; Viatkin, K.; Vargas, R.; Yigini, Y.; Omuto, C.; Malik, A. A.; Peralta, G.; Cuevas-Corona, R.; Di Paolo, L. E.; Luotto, I.; Liao, C.; Liang, Y.-S.; Saynes, V. S.; Huang, X.; Luo, Y.
10.1101/2023.08.20.552557 — ecology — Posted on 2023-08-29
422 Neural and behavioral organization of rapid eye movement sleep in zebrafish
Choudary, V.; Heller, C. R.; Aimon, S.; Schmid, L. d. S.; Robson, D. N.; Li, J. M.
10.1101/2023.08.28.555077 — neuroscience — Posted on 2023-08-29
424 β1 integrins regulate cellular behaviors and cardiomyocyte organization during ventricular wall formation
Miao, L.; Castillo, M.; Lu, Y.; Xiao, Y.; Liu, Y.; Burns, A. R.; Kumar, A.; Gunaratne, P.; DiPersio, C. M.; Wu, M.
10.1101/2023.08.28.555112 — developmental biology — Posted on 2023-08-29
428 A RAB7A Phosphoswitch Coordinates Rubicon Homology Protein Regulation of PINK1/Parkin-Dependent Mitophagy
Tudorica, D. A.; Basak, B. L. F.; Cordova, A. P.; Khuu, G.; Rose, K.; Lazarou, M.; Holzbaur, E.; Hurley, J. H.
10.1101/2023.08.28.555228 — cell biology — Posted on 2023-08-29
429 Huntingtin bundles and changes the local proteome of actin filaments in neurons
Carpentier, R.; Capizzi, M.; Kim, H.; Novion-Ducassou, J.; Denarier, E.; Blot, B.; Coute, Y.; Arnal, I.; Song, J.-J.; Humbert, S.
10.1101/2023.08.29.555277 — cell biology — Posted on 2023-08-29
430 Repair of DNA double-strand breaks leaves heritable impairment to genome function
Bantele, S. C.; Mordini, I.; Biran, A.; Alcaraz, N.; Wenger, A.; Krietenstein, N.; Groth, A.; Lukas, J.
10.1101/2023.08.29.555258 — cell biology — Posted on 2023-08-29
432 Characterizing Subcortical Structural Heterogeneity in Autism
MacDonald, D. N.; Bedford, S. A.; Olafson, E.; Park, M. T. M.; Devenyi, G. A.; Tullo, S.; Patel, R.; Anagnostou, E.; Baron-Cohen, S.; Bullmore, E. T.; Chura, L. R.; Craig, M. C.; Ecker, C.; Floris, D. L.; Holt, R. J.; Lenroot, R.; Lerch, J. P.; Lombardo, M. V.; Murphy, D. G. M.; Raznahan, A.; Ruigrok, A. N. V.; Smith, E.; Shinohara, R. T.; Spencer, M. D.; Suckling, J.; Taylor, M. J.; Thurm, A.; MRC AIMS Consortium, ; Lai, M.-C.; Chakravarty, M. M.
10.1101/2023.08.28.554882 — neuroscience — Posted on 2023-08-29
438 ATP13A3 Variants Promote Pulmonary Arterial Hypertension by Disrupting Polyamine Transport
Liu, B.; Azfar, M.; Legchenko, E.; West, J. A.; Martin, S.; Van den Haute, C.; Baekelandt, V.; Wharton, J.; Howard, L.; Wilkins, M.; Vangheluwe, P.; Morrell, N. W.; Upton, P. D.
10.1101/2023.08.29.554603 — cell biology — Posted on 2023-08-29
439 Predictive Systems Biology Modeling: Unraveling Host Metabolic Disruptions and Potential Drug Targets in Acute Viral Infections
Li, G.-H.; Han, F.; Luo, R.-H.; Li, P.; Chang, C.-J.; Xu, W.; Long, X.-Y.; Huang, J.-F.; Zheng, Y.-T.; Kong, Q.-P.; Xiao, W.
10.1101/2023.07.24.550423 — systems biology — Posted on 2023-08-29
441 Tau phosphorylated at serine 356 is associated with Alzheimer's disease pathology and can be lowered in mouse and human brain tissue using the NUAK inhibitor WZ4003
Taylor, L. W.; Simzer, E. M.; Pimblett, C.; Lacey-Solymar, O.; McGeachan, R. I.; Meftah, S.; Rose, J. L.; Spires-Jones, M. P.; Catterson, J. H.; Koch, H.; Liaquat, I.; Clarke, J. H.; Skidmore, J.; Booker, S. A.; Brennan, P. M.; Spires-Jones, T. L.; Durrant, C. S.
10.1101/2023.08.28.553851 — neuroscience — Posted on 2023-08-29
443 Respiratory modulations of cortical excitabilityand interictal spike timing in focal epilepsy - a case report
Kluger, D. S.; Erdbruegger, T.; Stier, C.; Hoeltershinken, M. B.; Saltafossi, M.; Unnwongse, K.; Wehner, T.; Wellmer, J.; Gross, J.; Wolters, C. H.
10.1101/2023.08.28.555061 — neuroscience — Posted on 2023-08-29
444 Sex-dependent effects of stress on insular cortex-to-nucleus accumbens synaptic plasticity
Gauthier, M.; Dugast, E.; Lardeux, V.; Letort, K.; Belnoue, L.; Balado, E.; Solinas, M.; Belujon, P.
10.1101/2023.08.28.555067 — neuroscience — Posted on 2023-08-29
445 Transcription factors operate on a limited vocabulary of binding motifs in Arabidopsis thaliana
Zenker, S.; Wulf, D.; Meierhenrich, A.; Becker, S.; Eisenhut, M.; Stracke, R.; Weisshaar, B.; Braeutigam, A.
10.1101/2023.08.28.555073 — systems biology — Posted on 2023-08-29
446 Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase
Colin, L.; Reyes, C.; Berthezene, J.; Maestroni, L.; Modolo, L.; Toselli, E.; Chanard, N.; Schaak, S.; Cuvier, O.; Gachet, Y.; Coulon, S.; Bernard, P.; Tournier, S.
10.1101/2022.03.18.484892 — cell biology — Posted on 2023-08-29
449 iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wildtype cells
Garcia-Gonzalez, I.; Gambera, S.; Regano, A.; Rocha, S. F.; Garcia-Ortega, L.; Lytvyn, M.; Sanchez-Munoz, M. S.; Garcia-Cabero, A.; Diago-Domingo, L.; Zagorac, I.; Luo, W.; Fernandez-Chacon, M.; Casquero-Garcia, V.; Lunella, F. F.; Benedito, R.
10.1101/2023.05.09.540000 — cell biology — Posted on 2023-08-29
451 UPP affects chloroplast development by interfering with chloroplast proteostasis
Scherer, V.; Bellin, L.; Schwenkert, S.; Lehmann, M.; Rinne, J.; Witte, C.-P.; Jahnke, K.; Richter, A. S.; Pruss, T.; Lau, A. S.; Leister, D.; Möhlmann, T.
10.1101/2023.08.28.555145 — molecular biology — Posted on 2023-08-29
452 Absorption changes in Photosystem II in the Soret band region upon the formation of the chlorophyll cation radical +
Boussac, A.; Sugiura, M.; Nakamura, M.; Nagao, R.; Noguchi, T.; Viola, S.; Rutherford, A. W.; Selles, J.
10.1101/2022.05.12.491653 — biophysics — Posted on 2023-08-29
454 Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale
Capitanchik, C.; Ireland, S.; Harston, A.; Cheshire, C.; Jones, D. M.; Lee, F. C. Y.; Ruiz de los Mozos, I.; Iosub, I. A.; Kuret, K.; Faraway, R.; Wilkins, O. G.; Arora, R.; Hallegger, M.; Modic, M.; Chakrabarti, A. M.; Luscombe, N. M.; Ule, J.
10.1101/2023.08.22.544179 — bioinformatics — Posted on 2023-08-29
456 Water fluxes contribute to growth patterning in shoot meristems
Alonso-Serra, J.; Cheddadi, I.; Kiss, A.; Cerutti, G.; Lionnet, C.; Godin, C.; Hamant, O.
10.1101/2023.08.27.554993 — plant biology — Posted on 2023-08-29
458 L-DOS47 enhances response to immunotherapy in pancreatic cancer tumor
Jardim-Perassi, B. V.; Irrera, P.; Abrahams, D.; Estrella, V. C.; Ordway, B.; Byrne, S. R.; Ojeda, A. A.; Whelan, C. J.; Kim, J.; Beatty, M. S.; Damgaci-Erturk, S.; Longo, D. L.; Gaspar, K. J.; Siegers, G. M.; Centeno, B. A.; Lau, J. Y. C.; Pilon-Thomas, S. A.; Gillies, R. J.; Ibrahim-Hashim, A.
10.1101/2023.08.28.555194 — cancer biology — Posted on 2023-08-28
460 Integration of Multiple Spatial-Omics Modalities Reveals Unique Insights into Molecular Heterogeneity of Prostate Cancer
Zhang, W.; Spotbeen, X.; Vanuytven, S.; Kint, S.; Sarretto, T.; Socciarelli, F.; Vandereyken, K.; Dehairs, J.; Idkowiak, J.; Wouters, D.; Alvira Larizgoitia, J. I.; Partel, G.; Ly, A.; de Laat, V.; Q. Mantas, M. J.; Gevaert, T.; Devlies, W.; Mah, C. Y.; Butler, L. M.; Loda, M.; Joniau, S.; De Moor, B.; Sifrim, A.; Ellis, S. R.; Voet, T.; Claesen, M.; Verbeeck, N.; Swinnen, J. V.
10.1101/2023.08.28.555056 — cancer biology — Posted on 2023-08-28
461 Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities
Kluiver, T. A.; Lu, Y.; Schubert, S. A.; Kraaier, L. J.; Ringnalda, F.; Lijnzaad, P.; DeMartino, J.; Megchelenbrink, W. L.; Amo-Addae, V.; Eising, S.; de Faria, F. W.; Munter, D. J.; van de Wetering, M.; Kerl, K.; Duiker, E.; van den Heuvel, M.; de Meijer, V. E.; de Kleine, R. H.; de Krijger, R. R.; Molenaar, J. J.; Margaritis, T.; Stunnenberg, H.; Zsiros, J.; Clevers, H.; Peng, W. C.
10.1101/2023.08.28.554783 — cancer biology — Posted on 2023-08-28
462 Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes
Knyazeva, A.; Li, S.; Corkery, D.; Shankar, K.; Herzog, L.; Zhang, X.; Singh, B.; Niggemeyer, G.; Grill, D.; Gilthorpe, J.; Gaetani, M.; Carlson, L.-A.; Waldmann, H.; Wu, Y.
10.1101/2023.08.28.555152 — cell biology — Posted on 2023-08-28
463 An autochthonous model of lung cancer in the Naked Mole-Rat (Heterocephalus glaber)
Kissil, J.; Shepard, A.; Troutman, S.; Hoxha, S.; Lester, D.; Khaled, W.; Smith, E. S. J.; Park, T.; Buffenstein, R.; Dongliang, D.; Teng, M. S. J.; Crish, C.; Tsai, K.; Flores, E.; Ventura, A.
10.1101/2023.08.28.555115 — cancer biology — Posted on 2023-08-28
464 Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes
Rose, K.; Jepson, T.; Shukla, S.; Maya-Romero, A.; Kampmann, M.; Xu, K.; Hurley, J. H.
10.1101/2023.08.28.555157 — cell biology — Posted on 2023-08-28
465 Synaptic plasticity via receptor tyrosine kinase / G protein-coupled receptor crosstalk
Lao-Peregrin, C.; Xiang, G.; Kim, J.; Srivastava, I.; Fall, A. B.; Gerhard, D. M.; Kohtala, P.; Kim, D.; Song, M.; Garcia-Marcos, M.; Levitz, J.; Lee, F. S.
10.1101/2023.08.28.555210 — cell biology — Posted on 2023-08-28
467 The human AMPKgamma3 R225W mutation does neither enhance basal AMPKgamma3-associated activity nor glycogen in human or mouse skeletal muscle
Eskesen, N. O.; Kjoebsted, R.; Birk, J. B.; Andersen, N. R.; Ringholm, S.; Pilegaard, H.; Pehmoeller, C. K.; Wojtaszewski, J. F. P.
10.1101/2023.08.28.555048 — molecular biology — Posted on 2023-08-28
471 Comparative transcriptional analysis of Candida auris biofilms following farnesol and tyrosol treatment
Jakab, A.; Kovacs, F.; Balla, N.; Nagy-Koteles, C.; Ragyak, A.; Nagy, F.; Borman, A. M.; Majoros, L.; Kovacs, R.
10.1101/2023.08.28.555140 — microbiology — Posted on 2023-08-28
473 Cholecystokinin-A Signaling Regulates Automaticity of Pacemaker Cardiomyocytes
Ruan, H.; Mandla, R.; Ravi, N.; Galang, G.; Soe, A. W.; Olgin, J. E.; Lang, D.; Vedantham, V.
10.1101/2023.01.24.525392 — physiology — Posted on 2023-08-28
474 TRβ Agonism Induces Tumor Suppression and Enhances Drug Efficacy in Anaplastic Thyroid Cancer in Female Mice
Gillis, N. E.; Cozzens, L. M.; Wilson, E. R.; Smith, N. M.; Tomczak, J. A.; Bolf, E. L.; Carr, F. E.
10.1101/2021.06.09.447689 — cancer biology — Posted on 2023-08-28
477 Sandy: A user-friendly and versatile NGS simulator to facilitate sequencing assay design and optimization
Miller, T. L. A.; Conceicao, H. B.; Mercuri, R. L.; Santos, F. R. C.; Barreiro, R.; Buzzo, J. L.; Rego, F. O.; Guardia, G. D. A.; Galante, P. A. F.
10.1101/2023.08.25.554791 — bioinformatics — Posted on 2023-08-28
480 Self-assembly vascularized human cardiac organoids model cardiac diseases in petri dishes and in mice
Zhong, Q.; He, Y.; Teng, L.; Zhang, Y.; Zhang, T.; Zhang, Y.; Li, Q.; Zhao, B.; Chen, D.; Zhong, Z.
10.1101/2023.08.26.554935 — cell biology — Posted on 2023-08-28
482 The cGAS-STING pathway is dispensable in a mouse model of LMNA-cardiomyopathy despite nuclear envelope rupture
En, A.; Bogireddi, H.; Thomas, B.; Stutzman, A.; Ikegami, S.; LaForest, B.; Almakki, O.; Pytel, P.; Moskowitz, I. P.; Ikegami, K.
10.1101/2023.08.28.555134 — molecular biology — Posted on 2023-08-28
485 Influenza A Virus Infections Sense Host Membrane Tension to Dynamically Tune Assembly
Partlow, E. A.; Jaeggi-Wong, A.; Planitzer, S. D.; Berg, N.; Li, Z.; Ivanovic, T.
10.1101/2023.08.28.555166 — microbiology — Posted on 2023-08-28
486 Cool temperature acclimation in toxigenic Microcystis aeruginosa PCC 7806 and its non-toxigenic mutant
Stark, G. F.; Martin, R. M.; Smith, L. F.; Wei, B.; Hellweger, F. L.; Bullerjahn, G. S.; McKay, R. M. L.; Boyer, G.; Wilhelm, S. W.
10.1101/2023.08.28.555099 — microbiology — Posted on 2023-08-28
491 Dissecting the neurotropism and neurovirulence of MPXV using human stem cell-based models
Bauer, L.; Giussani, S.; Palazzi, N.; Zare, F.; Colombo, E.; Pinci, F.; Leijten, L.; Smeenk, H.; Embregts, C. W. E.; Silva, M.; Spoor, J. K. H.; Dirven, C.; Gao, Z.; Bolleboom, A.; Verstrepen, B. E.; Schuele, L.; de Vrij, F. M. S.; Kushner, S. A.; Oude Munnink, B. B.; Davila-Velderrain, J.; van Riel, D.; Harschnitz, O.
10.1101/2023.08.25.554849 — microbiology — Posted on 2023-08-28
492 Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria
van den Biggelaar, R. H. G. A.; Walburg, K. V.; van den Eeden, S.; van Doorn, C. L. R.; Meiler, E.; de Ries, A. S.; Fusco, M. C.; Meijer, A. H.; Ottenhoff, T. H. M.; Saris, A.
10.1101/2023.08.28.555045 — microbiology — Posted on 2023-08-28
493 The beta 6 Integrin Negatively Regulates TLR7-Mediated Epithelial Immunity via Autophagy During Influenza A Virus Infection
Smith, M.; Meliopoulos, V. A.; Tan, S.; Bub, T.; Brigleb, P. H.; Sharp, B.; Crawford, J. C.; Prater, M. S.; Pruett-Miller, S. M.; Schultz-Cherry, S.
10.1101/2023.08.28.555098 — immunology — Posted on 2023-08-28
497 Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors
Ma, W.; del Rio, C. L.; Qi, L.; Prodanovic, M.; Mijailovich, S.; Zambataro, C.; Gong, H.; Shimkunas, R.; Gollapudi, S.; Nag, S.; Irving, T.
10.1101/2023.04.10.536292 — physiology — Posted on 2023-08-28
498 Sedentary behavior may accelerate aging through impact on epigenome and transcriptome: lessons from muscle inactivation in Drosophila larvae
Brener, A.; Lorber, D.; Reuveny, A.; Toledano, H.; Porat-Kuperstein, L.; Lebenthal, Y.; Weizman, E.; Olender, T.; Volk, T.
10.1101/2023.08.28.555053 — physiology — Posted on 2023-08-28
501 MAGinator enables strain-level quantification of de novo MAGs
Zachariasen, T.; Russel, J.; Petersen, C.; Vestergaard, G. A.; Shah, S.; Turvey, S.; Sorensen, S. J.; Lund, O.; Stokholm, J.; Brejnrod, A.; Thorsen, J.
10.1101/2023.08.28.555054 — bioinformatics — Posted on 2023-08-28
502 A simple method for developing lysine targeted covalent protein reagents
Gabizon, R.; Tivon, B.; Reddi, R. N.; Van Den Oetelaar, M.; Amartely, H.; Cossar, P. J.; Ottmann, C.; London, N.
10.1101/2023.08.28.553348 — biochemistry — Posted on 2023-08-28
503 Discovery and engineering of AiEvo2, a novel Cas12a nuclease for human gene editing applications
Sharrar, A.; Arake de Tacca, L.; Meacham, Z.; Staples-Ager, J.; Collingwood, T.; Rabuka, D.; Schelle, M.
10.1101/2023.08.28.554880 — biochemistry — Posted on 2023-08-28
506 Population interconnectivity shapes the distribution and complexity of chimpanzee cumulative culture
Gunasekaram, C.; Battiston, F.; Padilla-Iglesias, C.; van Noordwiijk, M. A.; Manica, A.; Bertranpetit, J.; Whiten, A.; van Schaik, C.; Vinicius, L.; Migliano, A. B.
10.1101/2023.08.14.553272 — evolutionary biology — Posted on 2023-08-28
509 Smart Leginon enables cryoEM screening automation across multiple grids
Sawh-Gopal, A.; Ishemgulova, A.; Chua, E. Y. D.; Aragon, M. F.; Mendez, J. H.; Eng, E. T.; Noble, A. J.
10.1101/2023.07.24.550406 — molecular biology — Posted on 2023-08-28
510 Oral Streptococci S. anginosus and S. mitis induce distinct morphological, inflammatory, and metabolic signatures in macrophages
Johnson, M. D. L.; Senthilkumar, S.; Gunda, V.; Reinartz, D.; Pond, K.; Santiago Raj, P. V.; Wilson, J. E.
10.1101/2023.08.28.555100 — microbiology — Posted on 2023-08-28
512 Structural and functional analyses of viral H2 protein of the vaccinia virus entry fusion complex
Kao, C.-F.; Liu, C.-Y.; Hsieh, C.-L.; Carillo, K. J. D.; Tzou, D.-L. M.; Wang, H.-C.; Chang, W.
10.1101/2023.08.28.555102 — microbiology — Posted on 2023-08-28
513 Sindbis Virus in Wild Pigeons, Thailand
Yodjan, N.; Wongwatthanacharat, S.; Khamsri, B.
10.1101/2023.08.28.555082 — microbiology — Posted on 2023-08-28
514 Inactivation of lmo0946 (sif) induces the SOS response and MGEs mobilization and silences the general stress response and virulence program in Listeria monocytogenes
Ladziak, M.; Prochwicz, E.; Gut, K.; Gomza, P.; Jaworska, K.; Scibek, K.; Mlynska-Witek, M.; Kadej-Zajaczkowska, K.; Lillebaek, E. M. S.; Kallipolitis, B. H.; Krawczyk-Balska, A.
10.1101/2023.08.28.555070 — microbiology — Posted on 2023-08-28
515 In Vivo Antiviral Efficacy of LCTG-002, a Pooled, Purified Human Milk Secretory IgA product, Against SARS-CoV-2 in a Murine Model of COVID-19
Mane, V.; Mehta, R.; Alvarez, N.; Sharma, V.; Park, S.; Fox, A.; DeCarlo, C.; Yang, X.; Perlin, D. S.; Powell, R. L.
10.1101/2023.08.25.554813 — immunology — Posted on 2023-08-28
516 Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females
Babey, M. E.; Krause, W. C.; Herber, C. B.; Chen, K.; Nikkannen, J.; Rodriquez, R.; Zhang, X.; Castro-Navarro, F.; Wang, Y.; Villeda, S.; Lance, N. E.; Scheller, E. L.; Chan, C. K. F.; Ambrosi, T. H.; Ingraham, H. A.
10.1101/2023.08.28.554707 — neuroscience — Posted on 2023-08-28
517 Decoding Fear or Safety and Approach or Avoidance by Brain-Wide Network Dynamics
Marques, D. B.; Rossignoli, M. T.; Mesquita, B. d. A.; Prizon, T.; Zacharias, L. R.; Ruggiero, R. N.; Leite, J. P.
10.1101/2022.10.13.511989 — neuroscience — Posted on 2023-08-28
520 Functional annotation of a divergent genome using sequence and structure-based homology.
Svedberg, D.; Winiger, R. R.; Berg, A.; Sharma, H.; Debrunner-Vossbrinck, B. A.; Vossbrinck, C. R.; Barandun, J.
10.1101/2023.08.27.554996 — genomics — Posted on 2023-08-28
522 Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
Vonada, A.; Wakefield, L.; Martinez, M.; Harding, C. O.; Grompe, M.; Tiyaboonchai, A.
10.1101/2023.08.27.554228 — genetics — Posted on 2023-08-28
525 Developmentally distinct architectures in top-down circuits
Klune, C. B.; Goodpaster, C. M.; Gongwer, M. W.; Gabriel, C. J.; Chen, R.; Jones, N. S.; Schwarz, L. A.; DeNardo, L. A.
10.1101/2023.08.27.555010 — neuroscience — Posted on 2023-08-28
528 Brain mechanisms underlying the emotion processing bias in treatment-resistant depression
Fan, X.; Mocchi, M.; Pascuzzi, B.; Xiao, J.; Metzger, B. A.; Mathura, R. K.; Hacker, C.; Adkinson, J. A.; Bartoli, E.; Elhassa, S.; Watrous, A. J.; Zhang, Y.; Goodman, W.; Pouratian, N.; Bijanki, K. R.
10.1101/2023.08.26.554837 — neuroscience — Posted on 2023-08-28
529 Identifying critical language planning regions with direct electrical brain stimulation
Castellucci, G. A.; Kovach, C. K.; Tabasi, F.; Christianson, D.; Greenlee, J. D.; Long, M. A.
10.1101/2023.08.26.554639 — neuroscience — Posted on 2023-08-28
531 Cell competition for cancer treatment with Urine Progenitor Cells
Bago, J. R.; Radhakrishnan, D.; Hrdinka, M.; Cichon, T.; Smolarczyk, R.; Charvatova, S.; Motais, B.; Giebel, S.; Hajek, R.
10.1101/2023.08.27.554858 — cancer biology — Posted on 2023-08-28
533 pyScoMotif: Discovery of similar 3D structural motifs across proteins
Cia, G.; Kwasigroch, J. M.; Stamatopoulos, B.; Rooman, M.; Pucci, F.
10.1101/2023.08.27.554982 — bioinformatics — Posted on 2023-08-28
536 A novel, N2-fixing cyanobacterium present and active in the global oceans
Cleveland, C. S.; Turk-Kubo, K. A.; Zhao, Y.; Zehr, J. P.; Webb, E. A.
10.1101/2023.08.27.555023 — genomics — Posted on 2023-08-28
537 Temporal dynamics and genomic programming of plasma cell fates
Vijay, G. K. M.; Zhou, M.; Thakkar, K.; Rothrauff, A.; Chawla, A.; Chen, D.; Lau, L.; Habib, P.; Chetal, K.; Chhibbar, P.; Fan, J.; Das, J.; Joglekar, A. V.; Borghesi, L.; Salomonis, N.; Xu, H.; Singh, H.
10.1101/2023.08.27.555004 — immunology — Posted on 2023-08-28
542 Prior Uncertainty Impedes Discrete Locomotor Adaptation
Jiang, A.; Grover, F.; Bucklin, M.; Deol, J.; Shafer, A.; Gordon, K. E.
10.1101/2023.08.27.554999 — neuroscience — Posted on 2023-08-28
544 Single-cell analysis of Rohon-Beard neurons implicates Fgf signaling in axon maintenance and cell survival
nechiporuk, a.; Tuttle, A. M.; Royer, L. J.; Kelly, J. J.; Wen, H.; Calistri, N.; Heiser, L. M.
10.1101/2023.08.26.554953 — neuroscience — Posted on 2023-08-28
545 Interrogating basal ganglia circuit function in Parkinson's disease and dystonia
Sumarac, S.; Spencer, K. A.; Steiner, L. A.; Fearon, C.; Haniff, E.; Kuhn, A. A.; Hodaie, M.; Kalia, S. K.; Lozano, A. M.; Fasano, A.; Hutchison, W. D.; Milosevic, L.
10.1101/2023.08.26.554666 — neuroscience — Posted on 2023-08-28
546 Reference genome sequence of the solitary bee Camptopoeum friesei Mocsary, 1894 (Hymenoptera, Andrenidae)
Stolle, E.; Guiglielmoni, N.; Kirangwa, J.; Kukowka, S.; Meitzel, T.; Mc Cartney, A.; Heilmann-Heimbach, S.; Becker, K.; Köhrer, K.; Böhne, A.
10.1101/2023.08.27.555015 — zoology — Posted on 2023-08-28
547 Structural and functional vascular dysfunction within brain metastases is linked to pembrolizumab inefficacy
Kim, A. E.; Lou, K. W.; Giobbie-Hurder, A.; Chang, K.; Gidwani, M.; Hoebel, K.; Patel, J.; Cleveland, M.; Singh, P.; Bridge, C.; Ahmed, S. R.; Bearce, B.; Liu, W.; Fuster-Garcia, E.; Lee, E.; Lin, N. U.; Overmoyer, B.; Wen, P. Y.; Nayak, L.; Cohen, J.; Dietrich, J.; Eichler, A.; Heist, R.; Krop, I.; Lawrence, D.; Ligibel, J.; Tolaney, S.; Mayer, E.; Winer, E.; Perrino, C. M.; Summers, E. J.; Mahar, M.; Oh, K.; Shih, H.; Cahill, D.; Rosen, B. R.; Yen, Y.-F.; Kalpathy-Cramer, J.; Martinez-Lage, M.; Sullivan, R. J.; Brastianos, P. K.; Emblem, K.; Gerstner, E. R.
10.1101/2023.08.25.554868 — cancer biology — Posted on 2023-08-28
555 An amplicon panel for high-throughput and low-cost genotyping of Pacific oyster
Sutherland, B. J. G.; Thompson, N. F.; Gujjula, K. R.; Carrasco, C. D.; Chadaram, S.; Chan, A. M.; Suttle, C. A.; Green, T. J.
10.1101/2023.08.26.554329 — genetics — Posted on 2023-08-28
556 Conservation value of low-elevation forests for birds in agroforestry-dominated landscapes in a biodiversity hotspot
Biswas, N.; Biniwale, S.; Sadekar, V.; Taneja, Y. V.; Suryawanshi, K.; Osuri, A. M.; Naniwadekar, R.
10.1101/2023.08.26.554947 — ecology — Posted on 2023-08-28
561 Evidence of virulence and antimicrobial resistance in Streptococcus pneumoniae serotype 16F lineages
Mokaya, J.; Mellor, K. C.; Murray, G. G.; Kalizangoma, A.; Lekhuleni, C.; Zar, H. J.; Nicol, M. P.; McGee, L.; Bentley, S. D.; Lo, S. W.; Dube, F.
10.1101/2023.08.25.554804 — genomics — Posted on 2023-08-28
562 Tick-borne zoonotic flaviviruses and Borrelia infections in wildlife hosts: what have field studies contributed?
Poisson, A.; Boulinier, T.; Bournez, L.; Gonzalez, G.; Migne, C. V.; Moutailler, S.; Faivre, B.; Metras, R.
10.1101/2023.08.25.554822 — ecology — Posted on 2023-08-28
563 Cell arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms
Dayton, H.; Kiss, J.; Wei, M.; Chauhan, S.; LaMarre, E.; Cornell, W. C.; Morgan, C. J.; Janakiraman, A.; Min, W.; Tomer, R.; Price-Whelan, A.; Nirody, J. A.; Dietrich, L. E.
10.1101/2023.06.20.545666 — microbiology — Posted on 2023-08-28
564 Differential cross-reactivity to the influenza B virus haemagglutinin underpins lineage-specific susceptibility between birth cohorts
Edler, P.; Schwab, L. S. U.; Aban, M.; Wille, M.; Spirason, N.; Deng, Y.-M.; Carlock, M. A.; Ross, T.; Juno, J. A.; Rockman, S.; Wheatley, A. K.; Kent, S. J.; Barr, I.; Price, D. J.; Koutsakos, M.
10.1101/2023.08.25.554879 — immunology — Posted on 2023-08-28
565 Global signal topography in the human brain differs systematically across the lifespan
Nomi, J.; Bzdok, D.; Li, J.; Bolt, T.; Chang, C.; Kornfeld, S.; Goodman, Z.; Yeo, B. T. T.; Spreng, R. N.; Uddin, L.
10.1101/2022.07.27.501804 — neuroscience — Posted on 2023-08-28
566 A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia
Kaurani, L.; Islam, M. R.; Heilbronner, U.; Krüger, D. M.; Zhou, J.; Methi, A.; Strauss, J.; Pradhan, R.; Burkhardt, S.; Pena, T.; Erlebach, L.; Bühler, A.; Budde, M.; Senner, F.; Kohshour, M. O.; Schulte, E. C.; Schmauss, M.; Reininghaus, E. Z.; Juckel, G.; Kronenberg-Versteeg, D.; Delalle, I.; Odoardi, F.; Flügel, A.; Schulze, T. G.; Falkai, P.; Sananbenesi, F.; Fischer, A.
10.1101/2023.03.21.533602 — neuroscience — Posted on 2023-08-28
567 FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Parekh, P.; Fan, C. C.; Frei, O.; Palmer, C. E.; Smith, D. M.; Makowski, C.; Iverson, J.; Pecheva, D.; Holland, D.; Loughnan, R.; Nedelec, P.; Thompson, W. K.; Hagler, D. J.; Andreassen, O. A.; Jernigan, T. L.; Nichols, T.; Dale, A. M.
10.1101/2021.10.27.466202 — neuroscience — Posted on 2023-08-28
570 iSanXoT: a Standalone Application for the Integrative Analysis of Mass Spectrometry-Based Quantitative Proteomics Data
Rodriguez, J. M.; Jorge, I.; Barrero-Rodriguez, R.; Magni, R.; Nunez, E.; Laguillo, A.; Devesa, C. A.; Lopez, J. A.; Camafeita, E.; Vazquez, J.
10.1101/2023.08.25.554773 — bioinformatics — Posted on 2023-08-28
571 ASTK: a machine learning-based integrative software for alternative splicing analysis
Huang, S.; He, J.; Yu, L.; Guo, J.; Jiang, S.; Sun, Z.; Cheng, L.; Chen, X.; Ji, X.; Zhang, Y.
10.1101/2023.01.03.522470 — bioinformatics — Posted on 2023-08-28
579 Mechanical signalling via membrane tension drives saltatory neuronal migration
Minegishi, T.; Hasebe, H.; Aoyama, T.; Naruse, K.; Takahashi, Y.; Inagaki, N.
10.1101/2023.08.28.555042 — cell biology — Posted on 2023-08-28
581 Epigenetic Reshaping through Damage: Promoting Cell Fate Transition by BrdU and IdU Incorporation
Li, C.; Chen, S.; Xu, X.; Guan, T.; Xu, A.; Li, C.; Yu, S.; Wu, H.; Pei, D.; Jing, L.
10.1101/2023.08.28.555083 — cell biology — Posted on 2023-08-28
582 The glucocorticoid receptor is a critical regulator of muscle satellite cell quiescence.
Rajgara, R.; AlSudais, H.; Saleh, A.; Brown, A.; Barrakad, I.; Blais, A.; Wiper-Bergeron, N.
10.1101/2023.08.27.555012 — cell biology — Posted on 2023-08-28
583 Absence of Lipopolysccharide (LPS) expression in Breast Cancer Cells
de Miranda, N. F.; Smit, V. T.; van der Ploeg, M.; Wesseling, J.; Neefjes, J.
10.1101/2023.08.28.555057 — pathology — Posted on 2023-08-28
586 A quantitative, genome-wide analysis in Drosophila reveals transposable elements' influence on gene expression is species-specific
Fablet, M.; Salces-Ortiz, J.; Jacquet, A.; Menezes, B. F.; Dechaud, C.; Veber, P.; Nous, C.; Rebollo, R.; Vieira, C.
10.1101/2022.01.20.477049 — genomics — Posted on 2023-08-28
587 Fitting individual-based models of spatial population dynamics to long-term monitoring data
Malchow, A.-K.; Fandos, G.; Kormann, U.; Grüebler, M. U.; Kery, M.; Hartig, F.; Zurell, D.
10.1101/2022.09.26.509574 — ecology — Posted on 2023-08-28
589 Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53
Godthi, A.; Min, S.; Srijit, D.; Cruz-Corchado, J.; Deonarine, A.; Misel-Wuchter, K.; Issuree, P. D.; Prahlad, V.
10.1101/2022.11.22.517560 — developmental biology — Posted on 2023-08-28
591 kCSD-python, reliable current source density estimation with quality control
Chintaluri, H. C.; Kowalska, M.; Sredniawa, W.; Czerwinski, M. B.; Dzik, J. M.; Jedrzejewska-Szmek, J.; Wojcik, D. K.
10.1101/708511 — neuroscience — Posted on 2023-08-28
593 3D Reconstruction of Murine Mitochondria Exhibits Changes in Structure Across Aging Linked to the MICOS Complex
Vue, Z.; Garza-Lopez, E.; Neikirk, K.; Katti, P.; Vang, L.; Beasley, H. K.; Shao, J.-q.; Marshall, A. G.; Crabtree, A.; Murphy, A. C.; Jenkins, B. C.; Prasad, P.; Evans, C. S.; Taylor, B. T.; Mungai, M.; Killion, M.; Stephens, D. C.; Christensen, T. A.; Lam, J.; Rodriguez, B.; Phillips, M. A.; Daneshgar, N.; Koh, H.-J.; Koh, A.; Davis, J.; Devine, N.; Muhammod, S.; Scudese, E.; Arnold, K.; Vanessa Chavarin, V.; Daniel Robinson, R.; Chakraborty, M.; Gaddy, J. A.; Wilson, G.; Zaganjor, E.; Kezos, J.; Dondi, C.; Reddy, A. K.; Glancy, B.; Kirabo, A.; Quintana, A. M.; Dai, D.-F.; Oncorr, K.; Murray
10.1101/2022.03.22.485341 — biophysics — Posted on 2023-08-28
594 Water fluxes contribute to growth patterning in shoot meristems
Alons-Serra, J.; Cheddadi, I.; Kiss, A.; Cerutti, G.; Lionnet, C.; Godin, C.; Hamant, O.
10.1101/2023.08.27.554993 — plant biology — Posted on 2023-08-28
595 WITHDRAWN: Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates
Greyling, N.; van der Watt, M.; Gwarinda, H.; van Heerden, A.; Greenhouse, B.; Leroy, D.; Niemand, J.; Birkholtz, L.-M.
10.1101/2023.07.20.549807 — biochemistry — Posted on 2023-08-28
596 SNP discovery by exome capture and resequencing in a pea genetic resource collection
Aubert, G.; Kreplak, J.; Leveugle, M.; Duborjal, H.; Klein, A.; Boucherot, K.; Vieille, E.; Chabert-Martinello, M.; Cruaud, C.; Bourion, V.; Lejeune-Henaut, I.; Pilet-Nayel, M.-L.; Bouchenak-Khelladi, Y.; Francillonne, N.; Tayeh, N.; Pichon, J.-P.; Riviere, N.; Burstin, J.
10.1101/2022.08.03.502586 — genomics — Posted on 2023-08-28
599 Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination
Zhao, X.; Qiu, T.; Huang, X.; Mao, Q.; Wang, Y.; Qiao, R.; Mao, T.; Wang, Y.; Li, J.; Luo, C.; Yoon, C.; Wang, X.; Li, C.; Cui, Y.; Zhao, C.; Li, M.; Chen, Y.; Cai, G.; Geng, W.; Hu, Z.; Cao, J.; Zhang, W.; Cao, Z.; Chu, H.; Sun, L.; Wang, P.
10.1101/2023.08.22.554373 — immunology — Posted on 2023-08-28
605 Abstract, modality-specific and experience-dependent coding of affect in the human brain
Lettieri, G.; Handjaras, G.; Cappello, E. M.; Setti, F.; Bottari, D.; Bruno, V.; Diano, M.; Leo, A.; Tinti, C.; Garbarini, F.; Pietrini, P.; Ricciardi, E.; Cecchetti, L.
10.1101/2023.08.25.554755 — neuroscience — Posted on 2023-08-28
612 Rapid in-situ diversification rates in Rhamnaceae explain the parallel evolution of high diversity in temperate biomes from global to local scales
Tian, Q.; Stull, G. W.; Kellermann, J.; Medan, D.; Nge, F. J.; Liu, S.; Kates, H. R.; Soltis, D. E.; Soltis, P. S.; Guralnick, R. P.; Folk, R. A.; Onstein, R. E.; Yi, T.-s.
10.1101/2023.08.26.554607 — evolutionary biology — Posted on 2023-08-28
613 CNTN4 modulates neural elongation through interplay with APP
Bamford, R. A.; Zuko, A.; Sprengers, J. J.; Post, H.; Taggenbrock, R. L. R. E.; Mehr, A.; Jones, O. J. R.; Kudzinskas, A.; Gandawijaya, J.; Eve, M.; Muller, U. C.; Kas, M. J.; Burbach, J. P. H.; Oguro-Ando, A.
10.1101/2023.08.25.554833 — neuroscience — Posted on 2023-08-28
614 NRF2 Regulates Contractile Vascular Smooth Muscle Cells Phenotypic Switching In Abdominal Aortic Aneurysm
Li, X.; Xiao, X.; Huang, X.; Song, F.; Chen, G.; Zhang, Y.; Liu, X.; Zhou, X.; Hong, Y.; He, H.; Meng, J.; Huang, X.; Zhong, L.
10.1101/2023.08.25.554907 — bioinformatics — Posted on 2023-08-28
616 Frailty is related to serum inflammageing markers: results from the VITAL study
van Sleen, Y.; Shetty, S. A.; van der Heiden, M.; Venema, M. C.; Gutierrez-Melo, N.; Toonen, E. J.; van Beek, J.; Buisman, A.-M.; van Baarle, D.; Sauce, D.
10.1101/2023.08.24.554610 — immunology — Posted on 2023-08-28
617 Altered Fhod3 Expression Involved in Progressive High-Frequency Hearing Loss via Dysregulation of Actin Polymerization Stoichiometry in The Cuticular Plate
Boussaty, E. C.; Ninoyu, Y.; Andrade, L.; Li, Q.; Takeya, R.; Sumimoto, H.; Ohyama, T.; Wahlin, K. J.; Manor, U.; Friedman, R. A.
10.1101/2023.07.20.549974 — neuroscience — Posted on 2023-08-28
618 Sequential breakdown of the complex Cf-9 leaf mould resistance locus in tomato by Fulvia fulva
de la Rosa, S.; Schol, C. R.; Peregrina, A. R.; Winter, D. J.; Hilgers, A. M.; Maeda, K.; Iida, Y.; Tarallo, M.; Jia, R.; Beenen, H. G.; Rocafort, M.; de Wit, P. J. G. M.; Bowen, J. K.; Bradshaw, R. E.; Joosten, M. H. A. J.; Bai, Y.; Mesarich, C. H.
10.1101/2023.08.27.554972 — microbiology — Posted on 2023-08-27
619 SNAP-25, but not SNAP-23, is essential for photoreceptor function and survival in mice
Huang, M.; Chow, C. H.; Gurdita, A.; Harada, H.; Pham Truong, V. Q. B.; Eide, S.; Sun, H.-S.; Feng, Z.-P.; Monnier, P. P.; Wallace, V. A.; Sugita, S.
10.1101/2023.08.25.554878 — neuroscience — Posted on 2023-08-27
624 A low-cost and open-source imaging platform reveals spatiotemporal insight into Arabidopsis leaf elongation and movement
Oskam, L.; Snoek, B. L.; Pantazopoulou, C. K.; van Veen, H.; Matton, S. E. A.; Dijkhuizen, R. F.; Pierik, R.
10.1101/2023.08.25.554752 — plant biology — Posted on 2023-08-27
625 The genetic basis of apple shape and size unraveled by digital phenotyping
Keller, B.; Jung, M.; Bühlmann-Schütz, S.; Hodel, M.; Studer, B.; Broggini, G. A.; Patocchi, A.
10.1101/2023.08.25.554767 — plant biology — Posted on 2023-08-27
626 Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery
Sedovy, M. W.; Leng, X.; Iqbal, F.; Renton, M. C.; Leaf, M.; Roberts, K.; Malek, A.; Arnold, W. S.; Wyatt, D. A.; Choate, C. W.; Rowe, J. F.; Baker, J. W.; Johnstone, S. R.; Joseph, M.
10.1101/2023.08.25.554690 — physiology — Posted on 2023-08-27
628 Sandy: A user-friendly and versatile NGS simulator to facilitate sequencing assay design and optimization
Miller, T. L. A.; Conceicao, H. B.; Mercuri, R. L.; Santos, F. R. C.; Barreiro, R.; Buzzo, J. L.; Rego, F. O.; Guardia, G. D. A.; Galante, P. A. F. F.
10.1101/2023.08.25.554791 — bioinformatics — Posted on 2023-08-27
629 Chloride intracellular channel (CLIC) proteins function as fusogens
Manori, B.; Vaknin, A.; Vankova, P.; Nitzan, A.; Zaidel-Bar, R.; Man, P.; Giladi, M.; Haitin, Y.
10.1101/2023.08.27.554981 — biochemistry — Posted on 2023-08-27
631 A Pooled Cell Painting CRISPR Screening Platform Enables de novo Inference of Gene Function by Self-supervised Deep Learning
Sivanandan, S.; Leitmann, B.; Lubeck, E.; Sultan, M. M.; Stanitsas, P.; Ranu, N.; Ewer, A.; Mancuso, J. E.; Phillips, Z. F.; Kim, A.; Bisognano, J. W.; Cesarek, J.; Ruggiu, F.; Feldman, D.; Koller, D.; Sharon, E.; Kaykas, A.; Salick, M. R.; Chu, C.
10.1101/2023.08.13.553051 — genomics — Posted on 2023-08-27
632 Identification of genetic drivers of plasma lipoproteins in the Diversity Outbred mouse population
Price, T. R.; Emfinger, C. H.; Schueler, K. L.; King, S.; Nicholson, R.; Beck, T.; Yandell, B. S.; Summers, S.; Holland, W. L.; Krauss, R. M.; Keller, M. P.; Attie, A. D.
10.1101/2023.08.26.554969 — genetics — Posted on 2023-08-27
633 ZFP57 is a regulator of postnatal growth and life-long health
Hanin, G.; Alsulaiti, B.; Costello, K. R.; Tavares, H.; Takahashi, N.; Mikheeva, L. A.; Freeman, A. K.; Patel, S.; Jenkins, B.; Koulman, A.; Ferguson-Smith, A. C.
10.1101/2023.08.27.554997 — developmental biology — Posted on 2023-08-27
634 LincRNAs enable germ cells differentiation by promoting PUF proteins condensation
Falk, R.; Gilad, N.; Achache, H.; Rappaport, Y.; Shabtai, R.; Ishtayeh, H.; Laura, W.; Tzur, Y. B.
10.1101/2023.08.27.554978 — developmental biology — Posted on 2023-08-27
635 Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines
del Moral-Sanchez, I.; Wee, E. G.; Xian, Y.; Lee, W.-H.; Allen, J. D.; Torrents de la Pena, A.; Rocha, R. d. P. F.; Ferguson, J.; Leon, A. N.; Koekkoek, S.; Schermer, E. E.; Burger, J. A.; Kumar, S.; Zwolsman, R.; Brinkkemper, M.; Aartse, A.; Eggink, D.; Han, J.; Yuan, M.; Crispin, M.; Ozorowski, G.; Ward, A. B.; Wilson, I. A.; Hanke, T.; Sliepen, K.; Sanders, R. W.
10.1101/2023.08.27.554987 — microbiology — Posted on 2023-08-27
636 Glymphatic Inhibition Exacerbates Tau Propagation in an Alzheimers Disease Model
Lopes, D. M.; Wells, J. A.; Ma, D.; Wallis, L.; Park, D.; Llewellyn, S. K.; Ahmed, Z.; Lythgoe, M. F.; Harrison, I. F.
10.1101/2023.08.25.554601 — neuroscience — Posted on 2023-08-27
637 Arrest of movement induced by Pedunculopontine-stimulation obstructs hippocampal theta rhythm
Kaur, J.; Komi, S. A.; Dmytriyeva, O.; Houser, G. A.; Bonfils, M. C. A.; Berg, R. W.
10.1101/2023.08.26.554923 — neuroscience — Posted on 2023-08-27
638 In vivo mapping of the deep and superficial whitematter connectivity in the chimpanzee brain
Chauvel, M.; Uszynski, I.; Herlin, B.; Popov, A.; Leprince, Y.; Mangin, J. F.; Hopkins, W. D.; Poupon, C.
10.1101/2023.08.25.554775 — neuroscience — Posted on 2023-08-27
640 A general exposome factor explains individual differences in functional brain network topography and cognition in youth
Keller, A. S.; Moore, T. M.; Luo, A.; Visoki, E.; Gatavins, M. M.; Shetty, A.; Cui, Z.; Fan, Y.; Feczko, E.; Houghton, A.; Li, H.; Mackey, A. P.; Miranda-Dominguez, O.; Pines, A.; Shinohara, R. T.; Sun, K. Y.; Fair, D. A.; Satterthwaite, T. D.; Barzilay, R.
10.1101/2023.08.25.554893 — neuroscience — Posted on 2023-08-27
641 Border-forming wound repair astrocytes
O'Shea, T. M.; Ao, Y.; Wang, S.; Ren, Y.; Cheng, A.; Kawaguchi, R.; Swarup, V.; Sofroniew, M. V.
10.1101/2023.08.25.554857 — neuroscience — Posted on 2023-08-27
642 Schisandrin B suppresses colon cancer growth by inducing cell cycle arrest and apoptosis via the CHOP signalling pathway
Co, V. A.; El-Nezami, H.; Liu, Y.; Twum, B.; Dey, P.; Cox, P. A.; Joseph, S.; Agbodjan, R.; Sabzichi, M.; Draheim, R.; Wan, M. L. Y.
10.1101/2023.08.27.554980 — pharmacology and toxicology — Posted on 2023-08-27
644 Von Willebrand Factor Synergizes with Tumor-Derived Extracellular Vesicles to Promote Gastric Cancer Metastasis
Wang, C.; Wang, M.; Cai, W.; Zhao, C.; Zhou, Q.; Zhang, X.-y.; Li, F.-x.; Zhang, C.-l.; Dang, Y.; Yang, A.-j.; Dong, J.; Li, M.
10.1101/2023.08.25.554906 — cancer biology — Posted on 2023-08-27
647 4D Single-Particle Tracking with Asynchronous Read-Out SPAD-Array Detector
Bucci, A.; Tortarolo, G.; Held, M. O.; Bega, L.; Perego, E.; Castagnetti, F.; Bozzoni, I.; Slenders, E.; Vicidomini, G.
10.1101/2023.08.25.554867 — biophysics — Posted on 2023-08-27
650 iSanXoT: a Standalone Application for the Integrative Analysis of Mass Spectrometry-Based Quantitative Proteomics Data
Rodriguez, J. M.; Jorge, I.; Barrero-Rodriguez, R.; Magni, R.; Nunez, E.; Laguillo, A.; Devesa, C. A.; Lopez, J. A.; Camafeita, E.; Vazquez, J.
10.1101/2023.08.25.554773 — bioinformatics — Posted on 2023-08-27
651 Structural Determinants of Tendon Function During Development and Their Sensitivity to Mechanical Stimulation
Peterson, B. E.; Canonicco Castro, M. L.; McCarthy, H.; Buckley, N.; Dunne, N.; Rolfe, R. A.; Murphy, P.; Szczesny, S.
10.1101/2023.08.25.554314 — bioengineering — Posted on 2023-08-27
652 Immune Response of Transplanted Kidney Tissues Assembled from Organoid Building Blocks
Borges, T. J.; Ganchiku, Y.; Aceves, J. O.; van Gaal, R.; Uzel, S. G. M.; Rubins, J. E.; Kobayashi, K.; Hiratsuka, K.; Tekguc, M.; Rosales, I. A.; Ribas, G. T.; Lima, K.; Gassen, R. B.; Morizane, R.; Lewis, J. A.; Riella, L. V.
10.1101/2023.08.26.551822 — bioengineering — Posted on 2023-08-27
653 Estimating the number of breeders from helminth larvae with genomic data.
Dennis, T. P. W.; Sands, W.; Opoku, M.; Debrah, A.; Debrah, L. B.; Pfarr, K.; Klarmann-Schulz, U.; Hoerauf, A.; Specht, S.; Scandale, I.; Ranford-Cartwright, L. C.; Lamberton, P. H. L.
10.1101/2023.08.25.554821 — genomics — Posted on 2023-08-27
654 MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations
Vermulst, M.; Paskvan, S.; Chung, C.; Franke, K.; Clegg, N.; Madeoy, J.; Long, A. N.; Gout, J.-F.; Bielas, J. H.
10.1101/2023.08.27.555013 — genetics — Posted on 2023-08-27
656 Competition and the century-long decline of a once common lizard, Sceloporus consobrinus
Murray, A.; Folfas, E. O.; Page, M. A.; Lange, Z. K.; Mruzek, J. L.; Frishkoff, L. O.
10.1101/2023.08.25.554877 — ecology — Posted on 2023-08-27
657 Mapping threatened Thai bovids provides opportunities for improved conservation outcomes in Asia
Horpiencharoen, W.; Hayman, D.; Marshall, J.; Lynam, A.; Muylaert, R.; John, R. S.; Ngoprasert, D.; Godfrey, A.; Riggio, A.; Gale, G. A.; Ash, E.; Bisi, F.; Cremonesi, G.; Clements, G. R.; Yindee, M.; Shwe, N. M.; Pin, C.; Gray, T. N. E.; Aung, S. S.; Nakbun, S.; Schuttler, S. G.; Steinmetz, R.; Phoonjampa, R.; Seuaturien, N.; Phumanee, W.
10.1101/2023.08.25.554763 — ecology — Posted on 2023-08-27
659 Energy flux couples sulfur isotope fractionation to proteomic and metabolite profiles in Desulfovibrio vulgaris
Leavitt, W. D.; Waldbauer, J.; Venceslau, S. S.; Sim, M. S.; Zhang, L.; Boidi, F. J.; Plummer, S.; Diaz, J. M.; Pereira, I. A. C.; Bradley, A. S.
10.1101/2023.08.27.555018 — microbiology — Posted on 2023-08-27
662 Histone Lactylation Drives CD8 T Cell Metabolism and Function
Raychaudhuri, D.; Singh, P.; Hennessey, M.; Tannir, A. J.; Chakraborty, B.; Natarajan, S. M.; Goswami, S.
10.1101/2023.08.25.554830 — immunology — Posted on 2023-08-27
664 Single-cell-resolved interspecies comparison identifies a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19
Peidli, S.; Nouailles, G.; Wyler, E.; Adler, J. M.; Kunder, S.; Voss, A.; Kazmierski, J.; Pott, F.; Pennitz, P.; Postmus, D.; Teixeira Alves, L. G.; Goffinet, C.; Gruber, A. D.; Bluethgen, N.; Witzenrath, M.; Trimpert, J.; Landthaler, M.; Praktiknjo, S. D.
10.1101/2023.08.25.551434 — immunology — Posted on 2023-08-27
665 Mesoscale functional architecture in medial posterior parietal cortex
Hira, R.; Townsend, L. B.; Smith, I. T.; Yu, C.-H.; Stirman, J. N.; Yu, Y.; Smith, S. L.
10.1101/2023.08.27.555017 — neuroscience — Posted on 2023-08-27
668 GDF15 is a dynamic biomarker of the Integrated Stress Response in the central nervous system
Asundi, J. S.; Zhang, C.; Donnelly-Roberts, D.; Solorio, J. Z.; Challagundla, M.; Connelly, C.; Boch, C.; Chen, J.; Richter, M.; Maneshi, M. M.; Swensen, A. M.; Lebon, L.; Schiffmann, R.; Sanyal, S.; Sidrauski, C.; Kolumam, G.; Baruch, A.
10.1101/2023.08.25.554842 — neuroscience — Posted on 2023-08-27
671 Neuronal tuning and population representations of shape and category in human visual cortex.
Bougou, V.; Vanhoyland, M.; Bertrand, A.; Van Paesschen, W.; Op de Beeck, H.; Janssen, P.; Theys, T.
10.1101/2023.08.25.554796 — neuroscience — Posted on 2023-08-27
672 Uncovering the Infection Strategy of Phyllachora maydis during Maize Colonization: A Comprehensive Analysis
Caldwell, D. L.; Da Silva, C. R.; McCoy, A. G.; Avila, H.; Bonkowski, J. C.; Chilvers, M.; Helm, M.; Telenko, D. E.; Iyer-Pascuzzi, A. S.
10.1101/2023.08.26.554799 — plant biology — Posted on 2023-08-27
674 Mutational order and epistasis determine the consequences of FBXW7 mutations during colorectal cancer evolution
Chan, D. K. H.; Mandal, A.; Collins, S. D.; Zhou, Y.; Owen, R.; Bundred, J.; Househam, J.; Graham, T. A.; Lu, X.; Buczacki, S. J. A.
10.1101/2023.08.25.554836 — cancer biology — Posted on 2023-08-27
675 HER2 overexpression initiates breast tumorigenesis non-cell-autonomously by inducing oxidative stress in the tissue microenvironment
Gurler, S. B.; Wagstaff, O.; Dimitrova, L.; Chen, F.; Pedley, R.; Weston, W.; Donaldson, I.; Telfer, B. A.; Novo, D.; Pavlou, K.; Taylor, G.; Ou, Y.; Williams, K. J.; Gilmore, A. P.; Brennan, K.; Ucar, A.
10.1101/2023.08.25.554770 — cancer biology — Posted on 2023-08-27
676 Long-term breast cancer response to CDK4/6 inhibition defined by TP53-mediated geroconversion
Kudo, R.; Safonov, A.; da Silva, E. M.; Li, Q.; Shao, H.; Will, M.; Fushimi, A.; Nakshatri, H.; Reis-Filho, J. S.; Goel, S.; Koff, A.; Weigelt, B.; Khan, Q. J.; Razavi, P.; Chandarlapaty, S.
10.1101/2023.08.25.554716 — cancer biology — Posted on 2023-08-27
677 Harnessing extracellular vesicles for efficient siRNA delivery in vitro and in vivo
Qiu, T.; Zhai, Y.; Yi, Y.; Wang, X.; Hu, R.; Niu, S.; Wang, C.; Cui, C.; Xu, K.; He, X.
10.1101/2023.08.26.554924 — cancer biology — Posted on 2023-08-27
683 Uncovering the molecular signatures of russet skin formation in Niagara grapevine (Vitis vinifera x Vitis labrusca)
Niederauer, G. F.; de Oliveira, G. L.; Aono, A. H.; Graciano, D. d. S. G.; Guerreiro, S. M. C.; Moura, M. F.; de Souza, A. P.
10.1101/2023.08.25.554330 — bioinformatics — Posted on 2023-08-27
686 Reengineering of a flavin-binding fluorescent protein using ProteinMPNN
Nikolaev, A.; Kuzmin, A.; Markeeva, E.; Kuznetsova, E.; Semenov, O.; Anuchina, A.; Remeeva, A.; Gushchin, I.
10.1101/2023.08.25.554855 — bioengineering — Posted on 2023-08-27
687 Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport
Watanabe, S.; Kise, Y.; Yonezawa, K.; Inoue, M.; Shimizu, N.; Nureki, O.; Inaba, K.
10.1101/2023.08.27.554937 — biochemistry — Posted on 2023-08-27
688 African elephants address one another with individually specific calls
Pardo, M. A.; Fristrup, K.; Lolchuragi, D. S.; Poole, J.; Granli, P.; Moss, C.; Douglas-Hamilton, I.; Wittemyer, G.
10.1101/2023.08.25.554872 — animal behavior and cognition — Posted on 2023-08-27
689 The genome of the colonial hydroid Hydractinia reveals their stem cells use a toolkit of genes shared with all animals
Schnitzler, C. E.; Chang, E. S.; Waletich, J.; Wong, W. Y.; Nguyen, A.-D.; Barreira, S.; Doonan, L.; Gonzalez, P.; Koren, S.; Gahan, J.; Quiroga-Artigas, G.; Sanders, S.; Bradshaw, B.; DuBuc, T.; Febrimarsa, F.; de Jong, D.; Nawrocki, E.; Larson, A.; Klasfeld, S.; Gornik, S.; Moreland, R. T.; Wolfsberg, T.; Phillippy, A. M.; Mullikin, J.; Simakov, O.; Cartwright, P.; Nicotra, M.; Frank, U.; Baxevanis, A. D.
10.1101/2023.08.25.554815 — genomics — Posted on 2023-08-27
690 Genomic insights into post-domestication expansion and selection of body size in ponies
Li, X.; Wang, Z.; Zhu, M.; Wang, B.; Teng, S.; Yan, J.; Yuan, P.; Cao, S.; Qu, X.; Wang, Z.; Choudhury, M. P.; Yang, X.; Bao, Q.; He, S.; Liu, L.; Zhao, P.; Jiang, J.; Xiang, H.; Fang, L.; Tang, Z.; Liao, Y.; Yi, G.
10.1101/2023.08.25.554910 — genomics — Posted on 2023-08-27
691 Decreased accuracy of forensic DNA mixture analysis for groups with lower genetic diversity
Flores, M.; Ly, C.; Ho, E.; Ceberio, N.; Felix, K.; Thorner, H. M.; Guardado, M.; Paunovich, M.; Godek, C.; Kalaydjian, C.; Rohlfs, R.
10.1101/2023.08.25.554311 — genetics — Posted on 2023-08-27
696 Coastal marine mammal conservation using thermal imaging-based detection systems
Richter, S.; Yurk, H.; Winterl, A.; Chmelnitsky, E.; Serra-Sogas, N.; O'Hara, P. D.; Zitterbart, D. P.
10.1101/2023.08.25.554754 — ecology — Posted on 2023-08-27
699 Social network centrality predicts dietary decisions in a wild bird population
McMahon, K.; Marples, N. M.; Spurgin, L. G.; Rowland, H. M.; Sheldon, B. S.; Firth, J. A.
10.1101/2023.08.25.554636 — ecology — Posted on 2023-08-27
701 Long-term impacts on estuarine benthic assemblages 4.2 years after a mine tailing spill in SE Brazil
Coppo, G. C.; Gabriel, F. A.; Mazzuco, A. C. A.; Queiroz, H. M.; Barcellos, D.; Ferreira, T. O.; Bernardino, A. F.
10.1101/2023.08.25.554820 — ecology — Posted on 2023-08-27
702 Using a multiscale lidar approach to determine variation in canopy structure from African forest elephant trails.
Keany, J. M.; Burns, P.; Abraham, A.; Jantz, P.; Makaga, L.; Saatchi, S.; Maisels, F.; Abernethy, K.; Doughty, C.
10.1101/2023.08.25.554381 — ecology — Posted on 2023-08-27
706 Spatiotemporal development of growth and death zones in expanding bacterial colonies driven by emergent nutrient dynamics
Kannan, H.; Sun, P.; Caglar, T.; Yao, P.; Taylor, B. R.; Sahu, K.; Ge, D.; Mori, M.; Warren, M.; Kleinfeld, D.; Dong, J.; Li, B.; Hwa, T.
10.1101/2023.08.27.554977 — microbiology — Posted on 2023-08-27
707 Tryptophan wasting and disease activity as a systems phenomenon in inflammation - an analysis across 13 chronic inflammatory diseases.
Harris, D. M.; Szymczak, S.; Schuchardt, S.; Labrenz, J.; Tran, F.; Welz, L.; Grasshoff, H.; Zirpel, H.; Suembuel, M.; Oumari, M.; Engelbogen, N.; Junker, R.; Conrad, C.; Thaci, D.; Frey, N.; Franke, A.; Weidinger, S.; Hoyer, B.; Rosenstiel, P.; Waschina, S.; Schreiber, S.; Aden, K.
10.1101/2023.08.25.554383 — immunology — Posted on 2023-08-27
708 Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population
Wang, A. Z.; Mashimo, B. L.; Schaettler, M. O.; Sherpa, N. D.; Leavitt, L. A.; Livingstone, A. J.; Khan, S. M.; Li, M.; Anzaldua-Campos, M.; Bradley, J. D.; Leuthardt, E. C.; Kim, A. H.; Dowling, J. L.; Chicoine, M. R.; Jones, P. S.; Choi, B. D.; Cahill, D. P.; Carter, B. S.; Petti, A. A.; Johanns, T. M.; Dunn, G. P.
10.1101/2023.08.25.554678 — immunology — Posted on 2023-08-27
709 Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy
Joers, V.; Murray, B. C.; McLaughlin, C.; Oliver, D.; Staley, H.; Coronado, J. E.; Achat-Mendes, C.; Golshani, S.; Kelly, S. D.; Goodson, M.; Lee, D.; Manfredsson, F. P.; Moore, B. M.; Tansey, M. G.
10.1101/2023.08.25.554814 — immunology — Posted on 2023-08-27
711 Abstract, modality-specific and experience-dependent coding of affect in the human brain
Lettieri, G.; Handjaras, G.; Cappello, E. M.; Setti, F.; Bottari, D.; Bruno, V.; Diano, M.; Leo, A.; Tinti, C.; Garbarini, F.; Pietrini, P.; Ricciardi, E.
10.1101/2023.08.25.554755 — neuroscience — Posted on 2023-08-27
712 NMDA receptors regulate neural progenitor cell proliferation and maturation in the zebrafish forebrain.
Napoli, A. J.; Laderwager, S.; Zoodsma, J. D.; Biju, B.; Mucollari, O.; Schubel, S. K.; Aprea, C.; Sayed, A.; Morgan, K.; Napoli, A.; Flanagan, S.; Wollmuth, L.; Sirotkin, H. I.
10.1101/2023.08.25.554812 — neuroscience — Posted on 2023-08-27
713 Optimizing learning via real-time neural decoding
Rudoler, J. H.; Bruska, J. P.; Chang, W.; Dougherty, M. R.; Katerman, B. S.; Halpern, D.; Diamond, N. B.; Kahana, M. J.
10.1101/2023.08.25.553563 — neuroscience — Posted on 2023-08-27
714 Beyond Lux: Methods for Species and Photoreceptor-Specific Quantification of Ambient Light for Mammals
McDowell, R. J.; Didikoglu, A.; Woelders, T.; Gatt, M. J.; Hut, R. A.; Brown, T. M.; Lucas, R. J.
10.1101/2023.08.25.554794 — neuroscience — Posted on 2023-08-27
717 S-Nitrosylation of CRTC1 in Alzheimer's disease impairs CREB-dependent gene expression induced by neuronal activity
Zhang, X.; Vlkolinsky, R.; Wu, C.; Dolatabadi, N.; Scott, H.; Prikhodko, O.; Blanco, M.; Lang, N.; Pina-Crespo, J.; Nakamura, T.; Roberto, M.; Lipton, S. A.
10.1101/2023.08.25.554320 — neuroscience — Posted on 2023-08-27
719 Muscle fibre size and myonuclear positioning in trained and aged humans
Battey, E.; Levy, Y.; Pollock, R. D.; Pugh, J. N.; Close, G. L.; Kalakoutis, M.; Lazarus, N. R.; Harridge, S. R.; Ochala, J.; Stroud, M. J.
10.1101/2023.08.25.551292 — physiology — Posted on 2023-08-27
721 Niche-specific macrophage loss promotes skin capillary aging
Mesa, K. R.; O'Connor, K. A.; Ng, C.; Salvatore, S.; Littman, D. R.
10.1101/2023.08.25.554832 — immunology — Posted on 2023-08-27
722 Contributions of individual satellite cells to muscle regeneration assessed using a confetti mouse model
Heemskerk, H.; Jagannathan, N. S.; Nasir, N. J. M.; Nguyen, B. P.; Sacadevan, K.; Matsudaira, P.; So, P. T.; Tucker-Kellogg, L.
10.1101/2023.08.25.554761 — physiology — Posted on 2023-08-27
723 The translation of a short open reading frame product within the human TUBA1B gene regulates cancer cell proliferation by importin-β
Tao, Y.; Bai, X.; Zhou, Y.; Zhao, Y.; Yang, L.; Zhang, S.; Yan, S.; Huang, X.; Schneider, E.; Zampetaki, A.; Margariti, A.; Giacca, M.; Arnold, J. N.; Zeng, L.; Cai, T.
10.1101/2023.08.26.554759 — cancer biology — Posted on 2023-08-27
725 Introducing π-HelixNovo for practical large-scale de novo peptide sequencing
Yang, T.; Ling, T.; Sun, B.; Liang, Z.; Xu, F.; Huang, X.; Xie, L.; He, Y.; Li, L.; He, F.; Wang, Y.; Chang, C.
10.1101/2023.07.15.549133 — bioinformatics — Posted on 2023-08-27
732 Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism
Anandachar, M. S.; Roy, S.; Sinha, S.; Agyekum, B.; Ibeawuchi, S.-R.; Gementera, H.; Amamoto, A.; Katkar, G. D.; Ghosh, P.
10.1101/2023.04.09.536168 — immunology — Posted on 2023-08-27
737 Human plasma cells engineered to secrete bispecifics drive effective in vivo leukemia killing
Hill, T. F.; Narvekar, P.; Asher, G.; Camp, N.; Thomas, K. R.; Tasian, S. K.; Rawlings, D. J.; James, R. G.
10.1101/2023.08.24.554523 — bioengineering — Posted on 2023-08-27
739 Divergent Pairwise Epistasis in the Context of Unstable Membrane Protein Variants
Chamness, L. M.; Kuntz, C. P.; McKee, A. G.; Penn, W. D.; Hemmerich, C. M.; Rusch, D. B.; Woods, H.; Dyotima, ; Meiler, J.; Schlebach, J. P.
10.1101/2023.08.25.554866 — biochemistry — Posted on 2023-08-27
743 Molecular fingerprints in the hippocampus of alcohol seeking during withdrawal
Pagano, R.; Salamian, A.; Skonieczna, E.; Wojtas, B.; Gielniewski, B.; Harda, Z.; Cały, A.; Havekes, R.; Abel, T.; Radwaska, K.
10.1101/2023.08.24.554622 — animal behavior and cognition — Posted on 2023-08-27
745 Phylogenetically diverse wild plant species use common biochemical strategies to thrive in the Atacama Desert
Dussarrat, T.; Nilo-Poyanco, R.; Moyano, T. C.; Prigent, S.; Jeffers, T. L.; Diaz, F. P.; Decros, G.; Audi, L.; Sondervan, V. M.; Shen, B.; Araus, V.; Rolin, D.; Shasha, D.; Coruzzi, G. M.; Gibon, Y.; Latorre, C.; Petriacq, P.; Gutierrez, R. A.
10.1101/2023.08.25.554423 — plant biology — Posted on 2023-08-27
747 Regulation of Non-Canonical Proteins Encoded by Small Open Reading Frames via the Nonsense-Mediated Decay Pathway.
PERIASAMY, P.; JOSEPH, C.; CAMPOS, A.; RAJANDRAN, S.; Batho, C.; Hudson, J. E.; Sivakumaran, H.; Kore, H.; Datta, K.; Yeong, J.; Gowda, H.
10.1101/2023.08.26.554966 — cell biology — Posted on 2023-08-26
748 Fe-TAMLs as a new class of small molecule peroxidase probes for correlated light and electron microscopy
Adams, S. R.; Mackey, M. R.; Ramachandra, R.; Deerinck, T. J.; Castillon, G. A.; Phan, S.; Hu, J.; Boassa, D.; Ngo, J. T.; Ellisman, M. H.
10.1101/2023.08.25.554352 — cell biology — Posted on 2023-08-26
754 Glycolytic Metabolon Assembly on Mitochondria via Hexokinase O-GlcNAcylation Promotes Metabolic Efficiency
Wang, H.; Vant, J.; Wu, Y.; Sanchez, R.; Micou, M. L.; Zhang, A.; Luczak, V.; Yu, S. B.; Jabbo, M.; Yoon, S.; Abushawish, A. A.; Ghassemian, M.; Griffis, E.; Hammarlund, M.; Singharoy, A.; Pekkurnaz, G.
10.1101/2023.08.26.554955 — cell biology — Posted on 2023-08-27
755 The cGAS-STING pathway regulates microglial chemotaxis in genome instability
Talbot, E. J.; Joshi, L.; Thornton, P.; Dezfouli, M.; Tsafou, K.; Perkinton, M.; Khoronenkova, S. V.
10.1101/2023.08.25.554654 — cell biology — Posted on 2023-08-27
762 α-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2
Wang, Y. J.; Yemelyanov, A.; Go, C. D.; Kim, S.; Quinn, J. M.; Flozak, A. S.; Le, P. M.; Liang, S.; Gingras, A.-C.; Ikura, M.; Ishiyama, N.; Gottardi, C. J.
10.1101/2023.08.25.554884 — cell biology — Posted on 2023-08-26
763 Control of microtubules in neuronal processes by profilin 1 and actomyosin
Cisterna, B. A.; Skruber, K.; Jane, M. L.; Camesi, C. I.; Nguyen, I. D.; Warp, P. V.; Black, J. B.; Butler, M. T.; Bear, J. E.; Read, T.-A.; Vitriol, E. A.
10.1101/2023.08.25.554891 — cell biology — Posted on 2023-08-26
764 4D intravital imaging studies iden1fy platelets as the predominant cellular procoagulant surface in a mouse model of hemostasis
Ballard-Kordeliski, A.; Lee, R. H.; O'Shaughnessy, E. C.; Kim, P. Y.; Jones, S. R.; Mackman, N.; Flick, M. J.; Paul, D. S.; Adalsteinsson, D.; Bergmeier, W.
10.1101/2023.08.25.554449 — cell biology — Posted on 2023-08-26
767 Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors
Chu, C.-W.; Caval, T.; Alisson-Silva, F.; Tankasala, A.; Guerrier, C.; Czerwieniec, G.; Laeubli, H.; Schwarz, F.
10.1101/2023.08.25.554811 — immunology — Posted on 2023-08-26
768 Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism
Anandachar, M. S.; Roy, S.; Sinha, S.; Agyekum, B.; Ibeawuchi, S.-R.; Gementera, H.; Amamoto, A.; Katkar, G. D.; Ghosh, P.
10.1101/2023.04.09.536168 — immunology — Posted on 2023-08-26
769 Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo
Busey, G. W.; Manjegowda, M. C.; Huang, T.; Iobst, W. H.; Naphade, S. S.; Kennedy, J. A.; Doyle, C. A.; Seegren, P. V.; Lynch, K. R.; Desai, B. N.
10.1101/2023.05.22.541802 — immunology — Posted on 2023-08-26
770 Unravelling ATP processing by the AAA+ protein p97 at the atomic level
Shein, M.; Hitzenberger, M.; Cheng, T.; Rout, S.; Leitl, K.; Sato, Y.; Zacharias, M.; Sakata, E.; Schuetz, A.
10.1101/2023.08.26.554927 — biophysics — Posted on 2023-08-26
774 CryoEM architecture of a native stretch-sensitive membrane microdomain
Kefauver, J. M.; Hakala, M.; Zou, L.; Alba, J.; Espadas Moreno, J.; Tettamanti, M. G.; Estrozi, L. F.; Vanni, S.; Roux, A.; Desfosses, A.; Loewith, R.
10.1101/2023.08.25.554800 — biophysics — Posted on 2023-08-26
778 An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin.
Hill, J. A.; Nyathi, Y. R.; Horrell, S.; von Stetten, D.; Axford, D.; Owen, R. L.; Beddard, G. S.; Pearson, A. R.; Ginn, H. M.; Yorke, B. A.
10.1101/2023.08.25.554810 — biochemistry — Posted on 2023-08-26
779 Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology
Filandr, F.; Sarpe, V.; Raval, S.; Crowder, D. A.; Khan, M. F.; Douglas, P.; Coales, S.; Viner, R.; Syed, A.; Tainer, J. A.; Lees-MIller, S. P.; Schriemer, D. C.
10.1101/2023.08.25.554852 — biochemistry — Posted on 2023-08-26
780 RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as platforms for viral replication
Kaundal, S.; Ramakrishnan, A.; Ayyar, B. V.; Shanker, S.; Kaur, G.; Crawford, S. E.; Pollet, J.; Stossi, F.; Estes, M. K.; Prasad, B. V. V.
10.1101/2023.08.24.554692 — biochemistry — Posted on 2023-08-26
784 Network-based prioritisation and validation of novel regulators of vascular smooth muscle cell proliferation in disease
Lambert, J.; Oc, S.; Worssam, M. D.; Häussler, D.; Figg, N. L.; Baxter, R.; Foote, K.; Finigan, A.; Mahbubani, K. T.; Bennett, M. R.; Krüger, A.; Spivakov, M.; Jorgensen, H. F.
10.1101/2023.08.25.554834 — molecular biology — Posted on 2023-08-26
785 Unravelling Genomic Origin of Lumpy Skin Disease Virus in Recent Outbreaks
Yadav, P.; Kumar, A.; Nath, S. S.; Shashidhar, G.; Joshi, M.; Puvar, A.; Sharma, S.; Raval, J.; Pandit, R.; Chavada, P.; Nagaraj, S.; Revanaiah, Y.; Patil, D.; K, R. S.; Raval, J.; Kanani, A.; Thakar, F.; Kumar, N.; Reddy, G. B. M.; Joshi, C.; Gulati, B. R.; Tatu, U. S.
10.1101/2023.08.25.554819 — microbiology — Posted on 2023-08-26
787 Tribbles1 and Cop1 cooperate to protect the host during in vivo mycobacterial infection
Hammond, F. R.; Lewis, A.; Pollara, G.; Tomlinson, G. S.; Noursadeghi, M.; Kiss-Toth, E.; Elks, P. M.
10.1101/2023.08.25.553505 — immunology — Posted on 2023-08-26
788 TRPM7-dependent electrical signals drive phagocytic clearance for effective anti-fungal defense
Stremska, M. E.; Stipes, E. J.; Jang, J. J.; Busey, G. W.; Iobst, W. H.; Seegren, P. V.; Kennedy, J.; Desai, B. N.
10.1101/2023.08.26.554944 — immunology — Posted on 2023-08-26
797 Tools for Genetic Engineering and Gene Expression Control in Novosphingobium aromaticivorans and Rhodobacter sphaeroides
Hall, A. N.; Hall, B. W.; Kinney, K. J.; Olsen, G. G.; Banta, A. B.; Noguera, D. R.; Donohue, T. J.; Peters, J. M.
10.1101/2023.08.25.554875 — microbiology — Posted on 2023-08-26
799 Local and dynamic regulation of neuronal glycolysis in vivo
Wolfe, A. D.; Koberstein, J. N.; Smith, C. B.; Stewart, M. L.; Hammarlund, M.; Hyman, A. A.; Stork, P. J. S.; Goodman, R. H.; Colon-Ramos, D. A.
10.1101/2023.08.25.554774 — neuroscience — Posted on 2023-08-26
801 CaMKII autophosphorylation but not downstream kinase activity is required for synaptic memory
CHEN, X.; Cai, Q.; zhou, j.; Pleasure, S. J.; Schulman, H.; Zhang, M.; Nicoll, R. A.
10.1101/2023.08.25.554912 — neuroscience — Posted on 2023-08-26
803 A hybrid machine learning and regression method for cell type deconvolution of spatial barcoding-based transcriptomic data
Liu, Y.; Li, N.; Qi, J.; Xu, G.; Zhao, J.; Wang, N.; Huang, X.; Jiang, W.; Justet, A.; Adams, T. S.; Homer, R.; Amei, A.; Rosas, I.; Kaminski, N.; Wang, Z.; Yan, X.
10.1101/2023.08.24.554722 — bioinformatics — Posted on 2023-08-26
806 Cellular and Molecular Basis of Leptin Resistance
Tan, B.; Hedbacker, K.; Kelly, L.; Zhang, Z.; Luo, J.-D.; Rabinowitz, J. D.; Friedman, J. M.
10.1101/2023.08.24.554526 — neuroscience — Posted on 2023-08-26
813 Do working forest easements work for conservation?
Thompson, J. R.; Kalinin, A.; Lee, L.; Pasquarella, V.; Plisinski, J.; Sims, K.
10.1101/2023.08.24.554638 — ecology — Posted on 2023-08-26
815 CAR T-cell therapy- Paving the way for sensitized kidney transplant patients.
Jarmi, T.; Luo, Y.; Attieh, R. M.; Qie, Y.; Gadd, M. E.; Hundal, T.; Mao, S.; Murthy, H. S.; Taner, B. C.; Kharfan-Dabaja, M.; Qin, H.
10.1101/2023.08.24.554644 — immunology — Posted on 2023-08-26
816 The association between brain serotonin 2A receptor binding and neuroticism in healthy individuals: A Cimbi database independent replication study
Hogsted, E. S.; Beliveau, V.; Ozenne, B.; Madsen, M. K.; Svarer, C.; Dam, V. N. H.; Johansen, A.; Fisher, P. M.; Knudsen, G. M.; Frokjaer, V. G.; Sankar, A.
10.1101/2023.08.24.554575 — neuroscience — Posted on 2023-08-26
820 Lung-innervating neurons expressing Tmc3 can induce broncho-constriction and dilation with direct consequences for the respiratory cycle
Kortmann, J.; Huang, K.; Tsai, M.-C.; Barck, K.; Jacobson, A.; Austin, C.; Dunlap, D.; Chalouni, C.; Jeet, S.; Balestrini, A.; Storm, E.; Wilson, M.; Deng, L.; Dourado, M.; Hackos, D.; Riol-Blanco, L.; Kaminker, J.; Turley, S.
10.1101/2023.08.24.554567 — neuroscience — Posted on 2023-08-26
821 Disentangling the spinal mechanisms of illusory heat and burning sensations in the Thermal Grill Illusion
Mitchell, A. G.; Fischer Ehmsen, J.; Elmstrom Christensen, D.; Stuckert, A.; Haggard, P.; Fardo, F.
10.1101/2023.08.24.554485 — neuroscience — Posted on 2023-08-26
823 Specialized structure of neural population codes in parietal cortex outputs
Safaai, H.; Wang, A. Y.; Kira, S.; Malerba, S. B.; Panzeri, S.; Harvey, C. D.
10.1101/2023.08.24.554635 — neuroscience — Posted on 2023-08-26
824 Lymphatic muscle cells are the innate pacemaker cells regulating mouse lymphatic collecting vessel contractions
Zawieja, S. D.; Pea, G. A.; Broyhill, S. E.; Bromert, K. H.; Norton, C. E.; Kim, H. J.; Li, M.; Castorena-Gonzalez, J. A.; Drumm, B. T.; Davis, M. J.
10.1101/2023.08.24.554619 — physiology — Posted on 2023-08-26
826 Spatial landmark detection and tissue registration with deep learning
Ekvall, M. N.; Bergenstrahle, L.; Andersson, A.; Olegard, J.; Czarnewski, P.; Kall, L.; Lundeberg, J.
10.1101/2023.08.24.554614 — bioinformatics — Posted on 2023-08-26
829 TCCIA: A Comprehensive Resource for Exploring CircRNA in Cancer Immunotherapy
Wang, S.; Xiong, Y.; Zhang, Y.; Wang, H.; Chen, M.; Li, J.; Luo, P.; Luo, Y.-H.; Hecht, M.; Frey, B.; Gaipl, U. S.; Li, X.; Zhao, Q.; Ma, H.; Zhou, J.-G.
10.1101/2023.08.24.554049 — bioinformatics — Posted on 2023-08-26
833 Both phenotypic and genotypic sex influence sex chromosome dosage compensation in a sex reversing lizard
Hanrahan, B. J.; Chang, J. K.; Lister, N. C.; Dissanayake, D. S. B.; Hammond, J. M.; Reis, A. L. M.; Deveson, I. W.; Ruiz-Herrera, A.; Patel, H. R.; Marshall Graves, J. A.; Georges, A.; Waters, P. D.
10.1101/2023.08.24.554710 — genomics — Posted on 2023-08-26
837 The role of microRNAs to understand sex-based differences in Alzheimer's disease
Llera-Oyola, J.; Carceller, H.; Andreu, Z.; Hidalgo, M. R.; Soler-Saez, I.; Gordillo, F.; Roson, B.; de la Iglesia, M.; Mancuso, R.; Guerini, F. R.; Mizokami, A.; Garcia-Garcia, F.
10.1101/2023.08.24.554586 — neuroscience — Posted on 2023-08-26
838 Mouse model of multiple sclerosis induced by disrupting vesicular transport in oligodendrocytes
Chow, C. H.; Huang, M.; Rai, J.; Harada, H.; Eide, S.; Sun, H.-S.; Feng, Z.-P.; Monnier, P. P.; Okamoto, K.; Zhang, L.; Sugita, S.
10.1101/2023.08.24.554669 — neuroscience — Posted on 2023-08-26
840 Cognitive effort increases the intensity of rewards
Wahab, M.; Mead, N.; Desmercieres, S.; Lardeux, V.; Dugast, E.; Baumeister, R. F.; Solinas, M.
10.1101/2023.08.24.554617 — neuroscience — Posted on 2023-08-26
841 Developmental adaptation of rod photoreceptor number via photoreception in melanopsin (OPN4) retinal ganglion cells
D'Souza, S. P.; Upton, B. A.; Eldred, K. C.; Glass, I.; Grover, K.; Ahmed, A.; Ngyuen, M.-T.; Gamlin, P.; Lang, R. A.
10.1101/2023.08.24.554675 — neuroscience — Posted on 2023-08-26
842 Evaluating models of the ageing BOLD response
Henson, R. N.; Olszowy, W.; Tsvetanov, K. A.; CamCAN, ; Zeidman, P.
10.1101/2023.08.24.554634 — neuroscience — Posted on 2023-08-26
844 Where's Whaledo: A software toolkit for array localization of animal vocalizations.
Snyder, E. R.; Solsona-Berga, A.; Baumann-Pickering, S.; Frasier, K. E.; Wiggins, S. M.; Hildebrand, J. A.
10.1101/2023.08.24.554565 — animal behavior and cognition — Posted on 2023-08-26
845 Source tracing of Leishmania donovani in emerging foci of visceral leishmaniasis in West Nepal
Monsieurs, P.; Cloots, K.; Uranw, S.; Banjara, M. R.; Ghimire, P.; Burza, S.; Hasker, E.; Dujardin, J.-C.; Domagalska, M. A.
10.1101/2023.08.22.554278 — microbiology — Posted on 2023-08-26
847 A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis
Valero, C.; Pinzan, C. F.; de Castro, P. A.; van Rhijn, N.; Earle, K.; Liu, H.; Horta, M. A. C.; Kniemeyer, O.; Krüger, T.; Pschibul, A.; Coemert, D. N.; Heinekamp, T.; Brakhage, A. A.; Steenwyk, J. L.; Mead, M. E.; Rokas, A.; Filler, S. G.; da Rosa-Garzon, N. G.; Cabral, H.; Deljabe, E.; Bromley, M. J.; Angeli, C. B.; Palmisano, G.; Ibrahim, A. S.; Gago, S.; dos Reis, T. F.; Goldman, G. H.
10.1101/2023.08.22.553365 — microbiology — Posted on 2023-08-26
849 Exploiting the Affimer platform against influenza A virus
Debski-Antoniak, O.; Flynn, A.; Klebl, D. P.; Tiede, C.; Wilson, I. A.; Muench, S. P.; Tomlinson, D.; Fontana, J.
10.1101/2023.08.22.554342 — microbiology — Posted on 2023-08-26
850 Contribution of bacterial and host factors to pathogen "blooming" in a gnotobiotic mouse model for Salmonella enterica serovar Typhimurium-induced enterocolitis
Beutler, M.; Eberl, C.; Garzetti, D.; Herp, S.; Münch, P.; Ring, D.; Dolowschiak, T.; Brugiroux, S.; Schiller, P.; Hussain, S.; Basic, M.; Bleich, A.; Stecher, B.
10.1101/2023.08.21.554185 — microbiology — Posted on 2023-08-26
851 Fecal microbiomics biomarkers for Chronic Wasting Disease
Didier, A.; Bourner, M.; Kleks, G.; Zolty, A.; Kumar, B.; Nichols, T.; Durynski, K.; Bender, S.; Gibison, M.; Murphy, L.; Ellis, J. C.; Dong, D. W.; Kashina, A.
10.1101/2023.08.21.554213 — microbiology — Posted on 2023-08-26
852 Connecting Thiamine Availability to the Microbial Community Composition in Chinook Salmon Spawning Habitats of the Sacramento River Basin
Suffridge, C. P.; Shannon, K. C.; Matthews, H.; Johnson, R.; Jeffres, C.; Mantua, N.; Ward, A. E.; Holmes, E.; Kindopp, J.; Aidoo, M.; Colwell, F.
10.1101/2023.08.22.554313 — microbiology — Posted on 2023-08-26
855 Long-term history dependence of growth rates of E. coli after nutrient shifts
Christodoulou, D.; Mukherjee, A.; Wegmann, R.; Pagano, A.; Sharma, V.; Linker, S. M.; Chang, Y.-F.; Palme, J. S.; Sauer, U.; Basan, M.
10.1101/2023.08.22.554350 — microbiology — Posted on 2023-08-26
856 The nutritional supplement taurine activates p53-dependent and independent tumor suppressor mechanisms in various cellular models of ovarian cancer
Centeno, D.; Farsinejad, S.; Kochetkova, E.; Volpari, T.; Klupczynska - Gabryszak, A.; Kung, D.; Polotaye, T.; Hyde, E.; Greenberg, M.; Pavlovic, T.; Alshehri, S.; Sullivan, W.; Plewa, S.; Vakifahmetoglu-Norberg, H.; Monsma, F. J.; Muller, P. A. J.; Matysiak, J.; Zaborowski, M.; DiFeo, A.; Andres-Martin, L.; Norberg, E.; Iwanicki, M.
10.1101/2023.02.24.529893 — cancer biology — Posted on 2023-08-26
863 cellsnake: a user-friendly tool for single-cell RNA sequencing analysis
Umu, S. U.; Rapp Vander-Elst, K.; Karlsen, V. T.; Chouliara, M.; Baekkevold, E. S.; Jahnsen, F. L.; Domanska, D.
10.1101/2023.05.03.539204 — bioinformatics — Posted on 2023-08-26
864 Segment Anything for Microscopy
Archit, A.; Nair, S.; Khalid, N.; Hilt, P.; Rajashekar, V.; Freitag, M.; Gupta, S.; Dengel, A.; Ahmed, S.; Pape, C.
10.1101/2023.08.21.554208 — bioinformatics — Posted on 2023-08-26
868 Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition
Gerrick, E. R.; Zlitni, S.; West, P. T.; Carter, M. M.; Mechler, C. M.; Olm, M. R.; Caffrey, E. B.; Li, J. A.; Higginbottom, S. K.; Severyn, C. J.; Kracke, F.; Spormann, A. M.; Sonnenburg, J. L.; Bhatt, A. S.; Howitt, M. R.
10.1101/2022.08.26.505490 — microbiology — Posted on 2023-08-26
869 Disruption of Aldehyde Dehydrogenase 2 protects against bacterial infection
Berry, S.; Espich, S.; Thuong, N. T. T.; Chang, X.; Dorajoo, R.; Khor, C. C.; Heng, C. K.; Yuan, J.-M.; Fox, D.; Anaya-Sanchez, A.; Tenney, L.; Chang, C. J.; Kotov, D. I.; Vance, R. E.; Dunstan, S. J.; Darwin, K. H.; Stanley, S. A.
10.1101/2023.08.24.554661 — microbiology — Posted on 2023-08-26
872 Association of NOTCH3 with Elastic Fiber Dispersion in the Infrarenal Abdominal Aorta of Cynomolgus Monkeys
Ito, S.; Amioka, N.; Franklin, M.; Wang, P.; Liang, C.-L.; Katsumata, Y.; Cai, L.; Temel, R. E.; Daugherty, A.; Lu, H. S.; Sawada, H.
10.1101/2023.03.04.530901 — pathology — Posted on 2023-08-26
874 Introducing π-HelixNovo for practical large-scale de novo peptide sequencing
Yang, T.; Ling, T.; Sun, B.; Liang, Z.; Xu, F.; Huang, X.; Xie, L.; He, Y.; Li, L.; He, F.; Wang, Y.; Chang, C.
10.1101/2023.07.15.549133 — bioinformatics — Posted on 2023-08-26
878 Spatio-temporal modeling of high-throughput multi-spectral aerial images improves agronomic trait genomic prediction in hybrid maize
Morales, N.; Anche, M. T.; Kaczmar, N. S.; Lepak, N.; Ni, P.; Romay, M. C.; Santantonio, N.; Buckler, E. S.; Gore, M. A.; Mueller, L. A.; Robbins, K. R.
10.1101/2022.10.18.512728 — genetics — Posted on 2023-08-26
879 A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes
Ellis, N. A.; Myers, K. S.; Tung, J.; Davidson Ward, A.; Johnston, K.; Bonnington, K. E.; Donohue, T. J.; Machner, M. P.
10.1101/2023.02.03.527066 — genetics — Posted on 2023-08-26
881 Two functionally distinct HEATR5 protein complexes are defined by fast-evolving co-factors in yeast
Marmorale, L. J.; Jin, H.; Reidy, T. G.; Palomino-Alonso, B.; Zysnarski, C.; Jordan-Javed, F.; Lahiri, S.; Duncan, M. C.
10.1101/2023.08.24.554671 — cell biology — Posted on 2023-08-26
883 Membrane remodeling properties of the Parkinson's disease protein LRRK2
Wang, X.; Espadas, J.; Wu, Y.; Cai, S.; Ge, J.; Shao, L.; Roux, A.; De Camilli, P.
10.1101/2022.08.10.503505 — cell biology — Posted on 2023-08-26
890 Paying attention to natural scenes in area V1
Lazar, A.; Klein, L.; Klon-Lipok, J.; Banyai, M.; Orban, G.; Singer, W.
10.1101/2023.03.21.533636 — neuroscience — Posted on 2023-08-26
891 Neural instructive signals for associative cerebellar learning
Silva, N. T.; Ramirez-Buritica, J.; Pritchett, D. L.; Carey, M. R.
10.1101/2022.04.18.488634 — neuroscience — Posted on 2023-08-26
893 SPIRO - the automated Petri plate imaging platform designed by biologists, for biologists
Ohlsson, J. A.; Leong, J. X.; Elander, P. H.; Ballhaus, F.; Holla, S.; Dauphinee, A. N.; Johansson, J.; Lommel, M.; Hofmann, G.; Betner, S.; Sandgren, M.; Schumacher, K.; Bozhkov, P. V.; Minina, E. A.
10.1101/2021.03.15.435343 — plant biology — Posted on 2023-08-26
896 Inhibition of autophagy as a novel therapy for the treatment of neurofibromatosis type 1 tumors
Stevens, M.; Wang, Y.; Bouley, S. J.; Mandigo, T. R.; Sharma, A.; Sengupta, S.; Housden, A. E.; Oltean, S.; Perrimon, N.; Walker, J. A.; Housden, B. E.
10.1101/2021.12.20.473481 — cancer biology — Posted on 2023-08-26
897 Caspase-2 protects against ferroptotic cell death
Dawar, S.; Benitez, M. C.; Lim, Y.; Dite, T. A.; Yousef, J. M.; Thio, N.; Garciaz, S.; Jackson, T. D.; Milne, J. V.; Dagley, L. F.; Phillips, W. A.; Kumar, S.; Clemons, N. J.
10.1101/2023.08.22.553791 — cancer biology — Posted on 2023-08-26
898 Cellular dynamics under time-varying conditions
Joshi, K.; Roy, S.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.03.07.531540 — biophysics — Posted on 2023-08-26
901 Scalable querying of human cell atlases via a foundational model reveals commonalities across fibrosis-associated macrophages
Heimberg, G.; Kuo, T. C.; DePianto, D.; Heigl, T.; Diamant, N.; Salem, O.; Scalia, G.; Biancalani, T.; Rock, J.; Turley, S.; Corrada Bravo, H.; Kaminker, J.; Vander Heiden, J. A.; Regev, A.
10.1101/2023.07.18.549537 — bioinformatics — Posted on 2023-08-26
903 Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins
Zeballos C., M. A.; Moore, H. J.; Smith, T. J.; Powell, J. E.; Ahsan, N. S.; Zhang, S.; Gaj, T.
10.1101/2023.04.07.536072 — bioengineering — Posted on 2023-08-26
904 Structure and design of Langya virus glycoprotein antigens
Wang, Z.; McCallum, M.; Yan, L.; Sharkey, W.; Park, Y.-J.; Dang, H. V.; Amaya, M.; Person, A.; Broder, C. C.; Veesler, D. J.
10.1101/2023.08.20.554025 — biochemistry — Posted on 2023-08-26
907 Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human
Schneider, S.; Kovacevic, A.; Mayer, M.; Dicke, A.-K.; Arevalo, L.; Koser, S. A.; Hansen, J. N.; Young, S.; Brenker, C.; Kliesch, S.; Wachten, D.; Kirfel, G.; Struenker, T.; Tuettelmann, F.; Schorle, H.
10.1101/2022.12.20.521208 — developmental biology — Posted on 2023-08-26
908 A stable microtubule bundle formed through an orchestrated multistep process controls quiescence exit
Laporte, D.; Massoni-Laporte, A.; LEfranc, C.; Dompierre, J.; Mauboules, D.; Nsamba, E. T.; Royou, A.; Gal, L.; Schuldiner, M.; Gupta, M.; Sagot, I.
10.1101/2023.05.02.539064 — cell biology — Posted on 2023-08-26
909 Novel function of U7 snRNA in the repression of HERV1/LTR12s and lincRNAs in human cells
Plewka, P.; Szczesniak, M. W.; Pasieka, R.; Stepien, A.; Wanowska, E.; Makalowska, I.; Raczynska, K. D.
10.1101/2023.08.25.554787 — molecular biology — Posted on 2023-08-26
911 Network-based prioritisation and validation of novel regulators of vascular smooth muscle cell proliferation in disease
Lambert, J.; Oc, S.; Worssam, M. D.; Häussler, D.; Figg, N. L.; Baxter, R.; Foote, K.; Finigan, A.; Bennett, M. R.; Krüger, A.; Spivakov, M.; Jorgensen, H. F.
10.1101/2023.08.25.554834 — molecular biology — Posted on 2023-08-26
913 A ubiquitous mobile genetic element disarms a bacterial antagonist of the gut microbiota
Sheahan, M. L.; Coyne, M. J.; Flores, K.; Garcia-Bayona, L.; Chatzidaki-Livanis, M.; Sundararajan, A.; Holst, A. Q.; Barquera, B.; Comstock, L. E.
10.1101/2023.08.25.553775 — microbiology — Posted on 2023-08-26
914 Anaerobic fungi in the tortoise alimentary tract illuminate early stages of host-fungal symbiosis and Neocallimastigomycota evolution
Pratt, C.; Meili, C.; Jones, A. L.; Jackson, D. K.; England, E. E.; Wang, Y.; Hartson, S.; Rogers, J.; Elshahed, M.; Youssef, N. H.
10.1101/2023.08.25.554870 — microbiology — Posted on 2023-08-26
915 Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in Pseudomonas aeruginosa
Schwartzkopf, C. M.; Taylor, V. L.; Groleau, M.-C.; Faith, D. R.; Schmidt, A. K.; Lamma, T. L.; Brooks, D. M.; Deziel, E.; Maxwell, K. L.; Secor, P. R.
10.1101/2023.08.25.554831 — microbiology — Posted on 2023-08-26
918 Rationally seeded computational protein design
Albanese, K. I.; Petrenas, R.; Pirro, F.; Naudin, E. A.; Borucu, U.; Dawson, W. M.; Scott, D. A.; Leggett, G. J.; Weiner, O. D.; Oliver, T.; Woolfson, D.
10.1101/2023.08.25.554789 — synthetic biology — Posted on 2023-08-26
920 High-Fidelity, Hyper-Accurate, and Evolved Mutants Rewire Atomic Level Communication in CRISPR-Cas9
Skeens, E.; Sinha, S.; Ahsan, M.; D'Ordine, A. M.; Jogl, G.; Palermo, G.; Lisi, G. P.
10.1101/2023.08.25.554853 — biophysics — Posted on 2023-08-26
921 RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as platforms for viral replication
PRASAD, B.; KAUNDAL, S.; Thachangattuthodi, A.; Ayyar, B. V.; Shanker, S.; Kaur, G.; Crawford, S.; Pollet, J.; Stossi, F.; Estes, M.
10.1101/2023.08.24.554692 — biochemistry — Posted on 2023-08-25
922 Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria
Alonso-del Valle, A.; Toribio-Celestino, L.; Quirant, A.; Tardio Pi, C.; DelaFuente, J.; Canton, R.; Rocha, E.; Ubeda, C.; Pena-Miller, R.; San Millan, A.
10.1101/2023.04.03.535338 — microbiology — Posted on 2023-08-25
926 Nitrate-driven anaerobic oxidation of ethane and butane by bacteria
Wu, M.; Li, J.; Lai, C.; Leu, A. O.; Sun, S.; Gu, R.; Erler, D. V.; Liu, L.; Li, L.; Tyson, G. W.; Yuan, Z.; McIlroy, S. J.; Guo, J.
10.1101/2023.08.24.554723 — microbiology — Posted on 2023-08-25
928 CD4 T cell Responses in the CNS during SIV infection
Elizaldi, S. R.; Verma, A.; Ma, Z.-M.; Ott, S.; Rajasundaram, D.; Cottrell, M. L.; Kashuba, A. D. M.; Ambrose, Z.; Lifson, J. D.; Morrison, J. H.; Iyer, S. S.
10.1101/2023.08.24.554055 — neuroscience — Posted on 2023-08-25
929 KCC2 as a novel biomarker and therapeutic target for motoneuron degenerative disease
Khademullah, C. S.; Bourbonnais, J.; Chaineau, M. M.; Castellanos Montiel, M. J.; Keramidis, I.; Legault, A.; Paquet, M.-E.; Abrahao, A.; Zinman, L.; Robertson, J.; Durcan, T.; Woodin, M. A.; Godin, A. G.; De Koninck, Y.
10.1101/2023.08.24.554410 — neuroscience — Posted on 2023-08-25
930 Dynamics of bacterial operons during genome-wide stresses
Jagadeesan, R.; Dash, S.; Palma, C.; Baptista, I. S. C.; Chauhan, V.; Makela, J.; Ribeiro, A. S.
10.1101/2023.08.24.554578 — systems biology — Posted on 2023-08-25
934 Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2
Rajasekaran, V.; Harris, B. T.; Osborn, R. T.; Smillie, C.; Donnelly, K.; Bacou, M.; Esiri-Bloom, E.; Ooi, L. Y.; Allan, M.; Walker, M.; Reid, S.; Meynert, A.; Grimes, G.; Blackmur, J. P.; Vaughan-Shaw, P. G.; Law, P. J.; Fernandez-Rozadilla, C.; Tomlinson, I. P.; Houlston, R.; Myant, K. B.; Din, F. V. N.; Dunlop, M. G.; Farrington, S. M.
10.1101/2023.08.24.554659 — genetics — Posted on 2023-08-25
937 Spatiotemporal dynamics of cytokines expression dictate fetal liver hematopoiesis.
Peixoto, M. M.; Soares-da-Silva, F.; Bonnet, V.; Ronteix, G.; Santos, R. F.; Mailhe, M.-P.; Feng, X.; Pereira, J.; Azzoni, E.; Anselmi, G.; de Bruijn, M.; Baroud, C.; Pinto-do-O, P.; Cumano, A.
10.1101/2023.08.24.554612 — developmental biology — Posted on 2023-08-25
940 Mucosal antibody responses to SARS-CoV-2 booster vaccination and breakthrough infection
Bhavsar, D.; Singh, G.; Sano, K.; Gleason, C.; Srivastava, K.; Carreno, J. M.; Simon, V.; Krammer, F.
10.1101/2023.08.24.554732 — immunology — Posted on 2023-08-25
941 Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice
Pan, A. L.; Audrain, M.; Sakakibara, E.; Joshi, R.; Zhu, X.; Wang, Q.; Wang, M.; Beckmann, N. D.; Schadt, E. E.; Gandy, S. E.; Zhang, B.; Ehrlich, M. E.; Salton, S. R.
10.1101/2023.08.24.554335 — neuroscience — Posted on 2023-08-25
945 Rise in frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021
Shanks, R. M. Q.; Atta, S.; Stella, N. A.; Sundar-Raj, C. V.; Romanowski, J. E.; Grewel, A. S.; Shanks, H. Q.; Mumper, S. M.; Dhaliwal, D. K.; Mammen, A.; Callaghan, J. D.; Calvario, R. C.; Romanowski, E. G.; Kowalski, R. P.; Zegans, M. E.; Jhanji, V.
10.1101/2023.08.22.554354 — microbiology — Posted on 2023-08-25
948 Identification of human skin microbiome odorants that manipulate mosquito landing behavior
Coutinho-Abreu, I. V.; Jamshidi, O.; Raban, R.; Atabakhsh, K.; Merriman, J. A.; Fischbach, M. A.; Akbari, O. S.
10.1101/2023.08.19.553996 — zoology — Posted on 2023-08-22
952 Identification of human skin microbiome odorants that manipulate mosquito landing behavior
Coutinho-Abreu, I. V.; Jamshidi, O.; Raban, R.; Atabakhsh, K.; Merriman, J. A.; Fischbach, M. A.; Akbari, O. S.
10.1101/2023.08.19.553996 — zoology — Posted on 2023-08-25
953 NYUS.2: an Automated Machine Learning Prediction Model for the Large-scale Real-time Simulation of Grapevine Freezing Tolerance in North America
Wang, H.; Moghe, G. D.; Kovaleski, A. P.; Keller, M.; Martinson, T. E.; Wright, A. H.; Franklin, J. L.; Hebert-Hache, A.; Provost, C.; Reinke, M.; Atucha, A.; North, M. G.; Helwi, P.; Centinari, M.; Londo, J. P.
10.1101/2023.08.21.553868 — plant biology — Posted on 2023-08-22
954 Parallel, Continuous Monitoring and Quantification of Programmed Cell Death in Plant Tissue
Silva Pinto Collins, A.; Kurt, H.; Duggan, C.; Cotur, Y.; Coatsworth, P.; Naik, A.; Kaisti, M.; Bozkurt, T. O.; Guder, F.
10.1101/2023.08.22.554256 — plant biology — Posted on 2023-08-22
956 A pectin-binding peptide with a structural and signaling role in the assembly of the plant cell wall
Schoenaers, S.; Lee, H. K.; Gonneau, M.; Faucher, E.; Levasseur, T.; Akary, E.; Claeijs, N.; Moussu, S.; Broyart, C.; Balcerowicz, D.; AbdElgawad, H.; Bassi, A.; Santa Cruz Damineli, D.; Costa, A.; Feijo, J. A.; Moreau, C.; Bonnin, E.; Cathala, B.; Santiago, J.; Hofte, H.; Vissenberg, K.
10.1101/2023.08.23.554416 — plant biology — Posted on 2023-08-23
958 Plant immunity activated and suppressed by a conserved effector protein family in mirid bug Riptortus pedestris
Zhou, J.; Yin, Z.; Shen, D.; Dong, Y.; Yang, Y.; Zhang, Q.; Ma, Y.; Pei, Y.; Lu, W.; Zhang, Y.; Ai, G.; Yang, D.-L.; Wang, Y.; Dou, D.; Xia, A.
10.1101/2023.08.22.554304 — plant biology — Posted on 2023-08-23
959 A New Feature of the Laboratory Model Plant Nicotiana benthamiana: Dead-End Trap for Sustainable Field Pest Control
Han, W.-H.; Wang, J.-X.; Zhang, F.-B.; Ji, S.-X.; Zhong, Y.-W.; Liu, Y.-Q.; Liu, S.-S.; Wang, X.-W.
10.1101/2023.08.23.554404 — plant biology — Posted on 2023-08-24
960 ATG8 delipidation is dispensable for plant autophagy
Holla, S.; Zou, Y.; Sabljic, I.; Ohlsson, J. A.; Leong, J. X.; Ballhaus, F.; Krebs, M.; Schumacher, K.; Bozhkov, P.; Minina, E. A.
10.1101/2023.08.23.554513 — plant biology — Posted on 2023-08-24
961 Germination responses to changing rainfall timing reveal potential climate vulnerability in a clade of wildflowers
Worthy, S. J.; Miller, A.; Ashlock, S. R.; Ceviker, E.; Maloof, J. N.; Strauss, S. Y.; Schmitt, J.; Gremer, J. R.
10.1101/2023.03.22.533835 — plant biology — Posted on 2023-08-25
962 Histone mark age of human tissues and cells
de Lima Camillo, L. P.; Asif, M. H.; Horvath, S.; Larshan, E.; Singh, R.
10.1101/2023.08.21.554165 — systems biology — Posted on 2023-08-22
964 Histone mark age of human tissues and cells
de Lima Camillo, L. P.; Asif, M. H.; Horvath, S.; Larschan, E.; Singh, R.
10.1101/2023.08.21.554165 — systems biology — Posted on 2023-08-23
973 Making Proteomics Accessible: RokaiXplorer for interactive analysis of phospho-proteomic data
Yılmaz, S.; Lopes, F. B. T. P.; Schlatzer, D.; Ayati, M.; Chance, M. R.; Koyutürk, M.
10.1101/2023.08.22.553639 — systems biology — Posted on 2023-08-25
975 Redox-enabled Electronic Interrogation and Feedback Control of Hierarchical and Networked Biological Systems
Wang, S.; Chen, C.-Y.; Rzasa, J. R.; Tsao, C.-Y.; Li, J.; VanArsdale, E.; Kim, E.; Zakaria, F. R.; Payne, G. F.; Bentley, W. E.
10.1101/2023.08.22.554301 — synthetic biology — Posted on 2023-08-22
976 Cell free expression in proteinosomes prepared from native protein-PNIPAAm conjugates
Gao, M.; Wang, D.; Wilsch-Brauninger, M.; Leng, W.; Schulte, J.; Morgner, N.; Appelhans, D.; Tang, T.-Y. D.
10.1101/2023.08.23.554401 — synthetic biology — Posted on 2023-08-23
981 Cell-extrinsic effects of Irf2 on cDC2 development
O'Connor, K. W.; Liu, T.; Kim, S.; Murphy, T.; Murphy, K. M.
10.1101/2023.08.24.554658 — immunology — Posted on 2023-08-25
984 Stratification of enterochromaffin cells by single-cell expression analysis
Song, Y.; Fothergill, L. J.; Lee, K. S.; Liu, B. Y.; Koo, A.; Perelis, M.; Diwakarla, S.; Callaghan, B.; Huang, J.; Wykosky, J.; Furness, J. B.; Yeo, G. W.
10.1101/2023.08.24.554649 — cell biology — Posted on 2023-08-25
986 Astroglia proliferate upon biogenesis of tunneling nanotubes and clearance of α-synuclein toxicities
Raghavan, A.; Kashyap, R.; P, S.; Jos, S.; Chatterjee, S.; Alex, A.; D' Souza, M. N.; Giridharan, M.; Muddashetty, R.; Manjithaya, R.; Padavattan, S.; Nath, S.
10.1101/2023.08.24.554645 — cell biology — Posted on 2023-08-25
988 Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma
Augustin, R. C.; Newman, S.; Li, A.; Joy, M.; Lyons, M.; Pham, M.; Lucas, P. C.; Smith, K.; Sander, C.; Isett, B.; Davar, D.; Najjar, Y. G.; Zarour, H. M.; Kirkwood, J. M.; Luke, J. J.; Bao, R.
10.1101/2023.08.24.554717 — cell biology — Posted on 2023-08-25
991 Antibody Neutralization of Emerging SARS-CoV-2: EG.5.1 and XBC.1.6
Wang, Q.; Guo, Y.; Zhang, R. M.; Ho, J.; Mohri, H.; Valdez, R.; Manthei, D. M.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2023.08.21.553968 — microbiology — Posted on 2023-08-25
992 Hypothetical gene Rv0495c regulates redox homeostasis in Mycobacterium tuberculosis
Pal, R.; Talwar, S.; Pandey, M.; Nain, V.; Sharma, T.; Tyagi, S.; Barik, V.; Chaudhary, S.; Gupta, S. K.; Kumar, Y.; Nanda, R.; Singhal, A.; Pandey, A. K.
10.1101/2023.08.22.554105 — microbiology — Posted on 2023-08-25
993 Long-term history dependence of growth rates of E. coli after nutrient shifts
Christodoulou, D.; Mukherjee, A.; Wegmann, R.; Pagano, A.; Sharma, V.; Linker, S. M.; Chang, Y.-F.; Palme, J. S.; Sauer, U.; Basan, M.
10.1101/2023.08.22.554350 — microbiology — Posted on 2023-08-25
994 Regulation of Lung Immune Tone by the Gut-Lung Axis via Dietary Fiber, Gut Microbiota, and Short-Chain Fatty Acids
Maruyama, D.; Liao, W.-I.; Tian, X.; Bredon, M.; Knapp, J.; Doan, T.; Tat, C.; Chassaing, B.; Bhargava, A.; Sokol, H.; Prakash, A.
10.1101/2023.08.24.552964 — immunology — Posted on 2023-08-25
995 Elephants develop wrinkles through both form & function
Schulz, A. K.; Kaufmann, L.; Reveyaz, N.; Ritter, C.; Hildebrandt, T.; Brecht, M. K.
10.1101/2023.08.24.554618 — physiology — Posted on 2023-08-25
997 Differential regulation of the proteome and phosphosproteome along the dorso-ventral axis of the early Drosophila embryo
Gomez, J. M.; Nolte, H.; Vogelsang, E.; Dey, B.; Takeda, M.; Giudice, G.; Faxel, M.; Cepraga, A.; Zinzen, R. P.; Krueger, M.; Petsalaki, E.; Wang, Y.-C.; Leptin, M.
10.1101/2023.08.24.554590 — developmental biology — Posted on 2023-08-25
1004 How do conservationists choose where to publish?
Yoh, N.; Holle, M. J. M.; Willis, J.; Rudd, L. F.; Fraser, I. M.; Verissimo, D.
10.1101/2023.08.24.554591 — scientific communication and education — Posted on 2023-08-25
1009 Remote sensing of emperor penguin abundance and breeding success
Winterl, A.; Richter, S.; Houstin, A.; Barracho, T.; Boureau, M.; Cornec, C.; Couet, D.; Cristofari, R.; Eiselt, C.; Fabry, B.; Krellenstein, A.; Mark, C.; Mainka, A.; Menard, D.; Morinay, J.; Pottier, S.; Schloesing, E.; Le Bohec, C.; Zitterbart, D. P.
10.1101/2023.08.24.554580 — ecology — Posted on 2023-08-25
1011 Prebiotic proanthocyanidins inhibit bile reflux-induced esophageal adenocarcinoma through reshaping the gut microbiome and esophageal metabolome
Weh, K. M.; Howard, C. L.; Zhang, Y.; Tripp, B. A.; Clarke, J.; Howell, A. B.; Rubenstein, J. H.; Abrams, J.; Westerhoff, M.; Kresty, L. A.
10.1101/2023.08.22.554315 — cancer biology — Posted on 2023-08-23
1014 Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR
Herlinger, A. L.; Michaelsen, G. L.; Sinigaglia, M.; Fratini, L.; Debom, G. N.; Braganhol, E.; de Farias, C. B.; Brunetto, A. L.; Brunetto, A. T.; Jaeger, M. d. C.; Roesler, R.
10.1101/2023.08.10.552840 — cancer biology — Posted on 2023-08-24
1015 Caspase-2 protects against ferroptotic cell death
Dawar, S.; Benitez, M. C.; Lim, Y.; Dite, T. A.; Yousef, J. M.; Thio, N.; Garciaz, S.; Jackson, T. D.; Milne, J. V.; Dagley, L. F.; Phillips, W. A.; Kumar, S.; Clemons, N. J.
10.1101/2023.08.22.553791 — cancer biology — Posted on 2023-08-24
1016 BIRC3: A Prognostic Predictor and Novel Therapeutic Target in TMZ-Resistant Glioblastoma Tumors
Morelli, M.; Franceschi, S.; Lessi, F.; Aretini, P.; Pastore, A.; Corradi, E.; Marranci, A.; Gambacciani, C.; Pieri, F.; Grimod, G.; Montemurro, N.; Giacomarra, M.; Menicagli, M.; Ferri, G.; Pasqualetti, F.; Sanson, M.; Picca, A.; Di Stefano, A. L.; Santonocito, O. S.; Mazzanti, C. M.
10.1101/2023.08.23.554432 — cancer biology — Posted on 2023-08-24
1018 AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis
McRee, S. K.; Bayer, A. L.; Pietruska, J.; Tsichlis, P.; Hinds, P. W.
10.1101/2023.08.24.554685 — cancer biology — Posted on 2023-08-24
1019 A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
Uo, T.; Ojo, K. K.; Sprenger, C. C.; Epilepsia, K. S.; Perera, B. G. K.; Damodarasamy, M.; Sun, S.; Kim, S.; Hogan, H. H.; Hulverson, M. A.; Choi, R.; Whitman, G. R.; Barrett, L. K.; Michaels, S. A.; Xu, L. H.; Sun, V. L.; Arnold, S. L. M.; Pang, H. J.; Nguyen, M. M.; Vigil, A.-L. B. G.; Kamat, V.; Sullivan, L. B.; Sweet, I. R.; Vidadala, R.; Maly, D. J.; Van Voorhis, W. C.; Plymate, S. R.
10.1101/2023.07.01.547355 — cancer biology — Posted on 2023-08-24
1020 Prolonging the Delivery of Influenza Virus Vaccine Improves the Quantity and Quality of the Induced Immune Responses in Mice
Beukema, M.; Gong, S.; Al-Jaawni, K.; de Vries-Idema, J. J.; Krammer, F.; Zhou, F.; Cox, R. J.; Huckriede, A. L. W.
10.1101/2023.08.24.554608 — immunology — Posted on 2023-08-25
1024 Dysregulation of chromatin via H3K27 methylation underpins differentiation arrest in Isocitrate dehydrogenase-mutant Acute Myeloid Leukaemia.
Silveira, D. R.; Chatzikyriakou, P.; Casares Alaez, P.; Mackie, S.; Hulks, R.; Yavorska, O.; Siejka-Zielinska, P.; Smith, A.; Metzner, M.; Usukhbayar, B.; Penard-Lacronique, V.; Song, C.-X.; Gandhi, A. K.; Vyas, P.; Milne, T.; Kriaucionis, S.; Hasan, M.; Quek, L.
10.1101/2023.08.24.554641 — cancer biology — Posted on 2023-08-25
1025 Improved dual-color GRAB sensors for monitoring dopaminergic activity in vivo
Zhuo, Y.; Luo, B.; Yi, X.; Dong, H.; Wan, J.; Cai, R.; Williams, J. T.; Qian, T.; Campbell, M. G.; Miao, X.; Li, B.; Wei, Y.; Li, G.; Wang, H.; Zheng, Y.; Watabe-Uchida, M.; Li, Y.
10.1101/2023.08.24.554559 — neuroscience — Posted on 2023-08-25
1028 Loss-of-function cancer-associated mutations in the EIF4G2 non-canonical translation initiation factor
Meril, S.; Bahlsen, M.; Eisenstein, M.; Savidor, A.; Levin, Y.; Bialik, S.; Pietrokovski, S.; Kimchi, A.
10.1101/2023.08.22.554280 — cancer biology — Posted on 2023-08-25
1029 Mechanics of biomimetic free-standing lipid membranes: Insights on lipid chemistry and bilayer elasticity
Griffo, A.; Sparn, C.; Lolicato, F.; Nolle, F.; Khangholi, N.; Seemann, R.; Fleury, J.-B.; Brinkmann, M.; Nickel, W.; Hahl, H.
10.1101/2023.08.21.554126 — biophysics — Posted on 2023-08-22
1036 Sub-membrane actin rings compartmentalize the plasma membrane
Rentsch, J.; Bandstra, S.; Sezen, B.; Sigrist, P. S.; Bottanelli, F.; Schmerl, B.; Shoichet, S. A.; Noe, F.; Sadeghi, M.; Ewers, H.
10.1101/2023.08.22.554239 — biophysics — Posted on 2023-08-23
1038 Cucurbituril Enhances Distance Measurements of Spin-Labeled Proteins
Yang, Z.; Stein, R. A.; Pink, M.; Madzelan, P.; Ngendahimana, T.; Rajca, S.; Wilson, M. A.; Eaton, S. S.; Eaton, G. R.; Mchaourab, H. S.; Rajca, A.
10.1101/2023.08.22.554361 — biophysics — Posted on 2023-08-23
1041 Dynamic traction force measurements of migrating immune cells in 3D matrices
Boehringer, D.; Condor, M.; Bischof, L.; Czerwinski, T.; Gampl, N.; Ngo, P. A.; Bauer, A.; Lopez-Posadas, R.; Franze, K.; Voskens, C.; Budday, S.; Mark, C.; Fabry, B.; Gerum, R.
10.1101/2022.11.16.516758 — biophysics — Posted on 2023-08-24
1043 Doubling the resolution of single-molecule localization microscopy with image scanning microscopy
Radmacher, N.; Nevskyi, O.; Gallea, J. I.; Thiele, J. C.; Gregor, I.; Rizzoli, S. O.; Enderlein, J.
10.1101/2023.08.23.554438 — biophysics — Posted on 2023-08-24
1045 Thermodynamic profiles for co-translational trigger factor function
Herling, T. W.; Cassaignau, A. M. E.; Wentink, A. S.; Peter, Q. A. E.; Kumar, P. C.; Kartanas, T.; Schneider, M. M.; Cabrita, L. D.; Christodoulou, J.; Knowles, T. P. J.
10.1101/2023.08.23.554456 — biophysics — Posted on 2023-08-24
1058 The floral development of the allotetraploid Coffea arabica L. correlates with a small RNA dynamic reprogramming.
Ribeiro, T. H. C.; Baldrich, P.; de Oliveira, R. R.; Fernandes-Brum, C. N.; Mathioni, S.; Cardoso, T. C. d. S.; Gomes, M. S.; Amaral, L. R.; de Oliveira, K. K. P.; dos Reis, G. L.; Meyers, B. C.; Chalfun-Junior, A.
10.1101/2023.08.23.554532 — plant biology — Posted on 2023-08-24
1060 Inference of gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations
Ishikawa, M.; Sugino, S.; Masuda, Y.; Tarumoto, Y.; Seto, Y.; Taniyama, N.; Wagai, F.; Yamauchi, Y.; Kojima, Y.; Kiryu, H.; Yusa, K.; Eiraku, M.; Mochizuki, A.
10.1101/2023.08.23.554254 — bioinformatics — Posted on 2023-08-23
1061 DiffDomain enables identification of structurally reorganized topologically associating domains
Hua, D.; Gu, M.; Zhang, X.; Du, Y.; Xie, H.; Qi, L.; Du, X.; Bai, Z.; Zhu, X.; Tian, D.
10.1101/2022.12.05.519135 — bioinformatics — Posted on 2023-08-23
1063 SC2Spa: a deep learning based approach to map transcriptome to spatial origins at cellular resolution
Liao, L.; Madan, E.; Palma, A.; Kim, H.; Kumar, A.; Bhoopathi, P.; Winn, R.; Trevino, J.; Brakebusch, C.; Gogna, R.; Won, K. J.
10.1101/2023.08.22.554277 — bioinformatics — Posted on 2023-08-23
1075 Multi-omics Analysis of Aging Liver Reveals Changes in Endoplasmic Stress and Degradation Pathways in Female Nonhuman Primates
Puppala, S.; Chan, J.; Zimmerman, K. D.; Hamid, Z.; Ampong, I.; Huber, H. F.; Li, G.; Jadhav, A. Y. L.; Li, C.; Nathanielsz, P. W.; Olivier, M.; Cox, L. A.
10.1101/2023.08.21.554149 — molecular biology — Posted on 2023-08-22
1077 The nasopharyngeal virome in adults with acute respiratory infection
Sandybayev, N.; Beloussov, V.; Strochkov, V.; Solomadin, M.; Granica, J.; Yegorov, S.
10.1101/2023.08.21.554191 — molecular biology — Posted on 2023-08-22
1078 Proportionality-based association metrics in count compositional data
McGregor, K.; Okaeme, N.; Khorasaniha, R.; Veniamin, S.; Jovel, J.; Miller, R.; Mahmood, R.; Graham, M.; Bonner, C.; Bernstein, C. N.; Arnold, D. L.; Bar-Or, A.; Hart, J.; Marrie, R. A.; O'Mahony, J.; Yeh, E. A.; Zhao, Y.; Banwell, B.; Waubant, E.; Knox, N.; Van Domselaar, G.; Zhu, F.; Mirza, A. I.; Tremlett, H.; Armstrong, H.
10.1101/2023.08.23.554468 — bioinformatics — Posted on 2023-08-24
1080 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus
Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.
10.1101/2023.08.22.554078 — molecular biology — Posted on 2023-08-22
1083 Structural insights into DNA Topoisomerase II of African Swine Fever Virus
Cong, J.; Xin, Y.; Kang, H.; Yang, Y.; Wang, C.; Li, X.; Rao, Z.; Chen, Y.
10.1101/2023.08.21.554066 — molecular biology — Posted on 2023-08-22
1085 Gate keeping the sebaceous gland.
Sachdeva, S.; Ahmed, A.; Proctor, G. B.; Miletich, I.
10.1101/2023.08.22.554243 — molecular biology — Posted on 2023-08-22
1086 Critical importance of DNA binding for CSL protein functions in fission yeast
Maresova, A.; Oravcova, M.; Hradilova, M.; Zemlianski, V.; Häsler, R.; Prevorovsky, M.
10.1101/2023.08.22.554308 — molecular biology — Posted on 2023-08-22
1090 Canonical and non-canonical contributions of human Dicer helicase domain in antiviral defense
Baldaccini, M.; Gaucherand, L.; Chane-Woon-Ming, B.; Messmer, M.; Gucciardi, F.; Pfeffer, S.
10.1101/2023.08.23.554407 — molecular biology — Posted on 2023-08-23
1097 Determining how MAFA and MAFB transcription factors activity is influenced by structural differences predicted by AlphaFold2
Tong, X.; Cha, J.; Guo, M.; Liu, J.-H.; Reynolds, G.; Loyd, Z.; Walker, E. M.; Soleimanpour, S. A.; Stein, R. A.; Mchaourab, H.; Stein, R.
10.1101/2023.08.23.554429 — molecular biology — Posted on 2023-08-23
1099 Oct4 redox sensitivity potentiates reprogramming and differentiation
Shen, Z.; Wu, Y.; Mana, A.; Evason, K. J.; Chandrasekharan, M. B.; Tantin, D.
10.1101/2023.02.21.529404 — molecular biology — Posted on 2023-08-24
1103 A fluorescence viewer for rapid molecular assay readout in space and low-resource terrestrial environments
Misquitta, K.; Miller, B. M.; Malecek, K.; Gleason, E.; Martin, K.; Walesky, C. M.; Foley, K.; Copeland, D. S.; Saavedra, E. A.; Kraves, S.
10.1101/2023.08.23.554556 — molecular biology — Posted on 2023-08-24
1104 Pioneer factor Pax7 initiates two-step cell-cycle dependent chromatin opening
Gouhier, A.; Dumoulin-Gagnon, J.; Lapointe-Roberge, V.; Harris, J.; Balsalobre, A.; DROUIN, J.
10.1101/2022.11.16.516735 — molecular biology — Posted on 2023-08-24
1107 Conservation of affinity rather than sequence underlies a dynamic evolution of the motif-mediated p53/MDM2 interaction in teleosts
Mihalic, F.; Arcila, D.; Pettersson, M. E.; Farkhondehkish, P.; Andersson, E.; Andersson, L.; Betancur-R, R.; Jemth, P.
10.1101/2023.08.24.554616 — molecular biology — Posted on 2023-08-24
1109 Beyond microRNAs: Analysis of chimeric reads characterises the diverse targetome of AGO2-mediated regulation.
Hejret, V.; Varadarajan, N. M.; Klimentova, E.; Gresova, K.; Giassa, I.-C.; Vanacova, S.; Alexiou, P.
10.1101/2023.08.24.554582 — molecular biology — Posted on 2023-08-24
1113 N4-Hydroxycytidine/Molnupiravir Inhibits RNA-Virus Induced Encephalitis by Producing Mutated Viruses with Reduced Fitness
Ojha, D.; Hill, C. S.; Zhou, S.; Evans, A. B.; Leung, J. M.; Lewis, C. S.; Amblard, F.; Schinazi, R. F.; Baric, R. S.; Peterson, K. E.; Swanstrom, R.
10.1101/2023.08.22.554316 — microbiology — Posted on 2023-08-23
1115 Effects of biological and environmental factors on filovirus serology in bats in Guinea
Champagne, M.; Cappelle, J.; Caron, A.; Pouliquen, T.; Samoura, A.; Doumbouya, M. I.; Thaurignac, G.; Ayouba, A.; Keita, A. K.; Peeters, M.; Bourgarel, M.; De Nys, H. M.
10.1101/2023.08.23.554395 — microbiology — Posted on 2023-08-23
1117 Innate immune control of influenza virus interspecies adaptation
Denz, P. J.; Speaks, S.; Kenney, A. D.; Eddy, A. C.; Papa, J. L.; Roettger, J.; Scace, S. C.; Hemann, E. A.; Forero, A.; Webby, R. J.; Bowman, A. S.; Yount, J. S.
10.1101/2023.08.23.554491 — microbiology — Posted on 2023-08-23
1125 Absolute Quantification of Microbiota in Shotgun Sequencing Using Host Cells or Spike-Ins
Wallace, A.; Ling, H.; Gatenby, S.; Pruden, S.; Neeley, C.; Harland, C.; Couldrey, C.
10.1101/2023.08.23.554046 — microbiology — Posted on 2023-08-24
1126 Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites
Dirkx, L.; Van Acker, S.; Nicolaes, Y.; Cunha, J. L. R.; Ahmad, R.; Caljon, B.; Imamura, H.; Ebo, D. G.; Jeffares, D.; Sterckx, Y. G.-J.; Maes, L.; Hendrickx, S.; Caljon, G.
10.1101/2023.08.23.554403 — microbiology — Posted on 2023-08-24
1131 The histidine kinase NahK regulates pyocyanin production through the PQS system
Mendoza, A. G.; Guercio, D.; Smiley, M. K.; Sharma, G. K.; Withorn, J. M.; Hudson-Smith, N. V.; Ndukwe, C.; Dietrich, L. E. P.; Boon, E.
10.1101/2023.08.23.554518 — microbiology — Posted on 2023-08-24
1133 Comparison of SARS-CoV-2 variants in primary human nasal cultures indicates Delta as most cytopathic and Omicron as fastest replicating
Tanneti, N. S.; Patel, A. K.; Tan, L. H.; Marques, A. D.; Perera, R. A.; Sherrill-Mix, S.; Kelly, B. J.; Collman, R. G.; Rodino, K.; Lee, C.; Bushman, F. D.; Cohen, N. A.; Weiss, S. R.
10.1101/2023.08.24.553565 — microbiology — Posted on 2023-08-24
1134 Disruption of Aldehyde Dehydrogenase 2 protects against 1 bacterial infection
Berry, S.; Espich, S.; Thuong, N. T. T.; Chang, X.; Dorajoo, R.; Khor, C. C.; Heng, C. K.; Yuan, J.-M.; Fox, D.; Anaya-Sanchez, A.; Tenney, L.; Chang, C. J.; Kotov, D. I.; Vance, R. E.; Dunstan, S. J.; Darwin, K. H.; Stanley, S. A.
10.1101/2023.08.24.554661 — microbiology — Posted on 2023-08-24
1136 Targeted lipid A modification of Shigella vaccine strains reduced endotoxicity without compromising immunogenicity or invasiveness
Sherman, M. E.; Michalski, J.; Das, S.; Yang, H.; Barnoy, S.; Chandrasekaran, L.; Venkatesan, M.; Ernst, R. K.
10.1101/2023.08.24.554604 — microbiology — Posted on 2023-08-24
1139 Gut microbiome remains stable following COVID-19 vaccination in healthy and immuno-compromised individuals
Boston, R. H.; Guan, R.; Baier, S.; Kalmar, L.; Horner, E. C.; Beristain-Covarrubias, N.; Yam-Puc, J. C.; Gerber, P. P.; Faria, L.; Kuroshchenkova, A.; Lindell, A. E.; Blasche, S.; Correa-Noguera, A.; Elmer, A.; Saunders, C.; Bermperi, A.; Jose, S.; Kingston, N.; COVID-19 BioResource Collaboration, ; Grigoriadou, S.; Staples, E.; Buckland, M.; Parkinson, C.; Lear, S.; Matheson, N. J.; Benes, V.; Thaventhiran, J. E.; Patil, K. R.
10.1101/2023.08.23.554506 — microbiology — Posted on 2023-08-24
1140 Diversity of Bathyarchaeia viruses in metagenomes and virus-encoded CRISPR system components
DUAN, C.; Liu, Y.; Liu, Y.; Liu, L.; Cai, M.; Zeng, Q.; Koonin, E. V.; Krupovic, M.; Li, M.
10.1101/2023.08.24.554615 — microbiology — Posted on 2023-08-24
1141 MiDAS 5: Global diversity of bacteria and archaea in anaerobic digesters
Dueholm, M. K. D.; Andersen, K. S.; Petersen, A.-K. C.; Rudkjoebing, V.; MiDAS Global Consortium for Anaerobic Digesters, ; Nielsen, P. H.
10.1101/2023.08.24.554448 — microbiology — Posted on 2023-08-24
1142 VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection
Tyagi, S.; Sadhu, S.; Sharma, T.; Paul, A.; Pandey, M.; Nain, V.; Rathore, D.; Chatterjee, S.; Awasthi, A.; Pandey, A. K.
10.1101/2023.08.24.554572 — microbiology — Posted on 2023-08-25
1143 A chromosome-level genome assembly of Zasmidium syzygii isolated from banana leaves
van Westerhoven, A.; Mehrabi, R.; Talebi, R.; Steentjes, M.; Corcolon, B.; Chong, P.; Kema, G.; Seidl, M. F.
10.1101/2023.08.24.554682 — microbiology — Posted on 2023-08-25
1144 A simple solid media assay for detection of synergy between bacteriophages and antibiotics
Khong, E.; Oh, J.; Jiminez, J. M.; Liu, R.; Dunham, S. J. B.; Monsibais, A.; Rhoads, A.; Ghatbale, P.; Garcia, A.; Cobian-Güemes, A. G.; Blanc, A.; Chiu, M.; Kuo, P.; Proost, M.; Kline, A.; Aslam, S.; Schooley, R.; Whiteson, K.; Fraley, S.; Pride, D. T.
10.1101/2023.08.23.554535 — microbiology — Posted on 2023-08-25
1145 Phage transcriptional regulator X (PtrX)-mediated augmentation of toxin production and virulence in Clostridioides difficile strain R20291
Gong, J.-J.; Huang, I.-H.; Su, S.-W.; Xie, S.-X.; Liu, W.-Y.; Huang, C.-R.; Hung, Y. P.; Wu, S.-R.; Tsai, P. J.; Ko, W. C.; Chen, J.-W.
10.1101/2023.08.24.554564 — microbiology — Posted on 2023-08-25
1147 Olfactomedin-4+ neutrophils exacerbate intestinal epithelial damage and worsen host survival after Clostridioides difficile infection.
Huber, A. D.; Jose, S.; Kassam, A.-F.; Weghorn, K.; Powers-Fletcher, M.; Sharma, D.; Mukherjee, A.; Mathew, A.; Kulkarni, N.; Chandramouli, S.; Alder, M.; Madan, R.
10.1101/2023.08.21.553751 — immunology — Posted on 2023-08-22
1148 Heterologous sarbecovirus receptor binding domains as scaffolds for SARS-CoV-2 receptor binding motif presentation
Hauser, B. M.; Sangesland, M.; Lam, E. C.; St. Denis, K. J.; Sheehan, M. L.; Vu, M. L.; Cheng, A. H.; Balazs, A. B.; Lingwood, D.; Schmidt, A.
10.1101/2023.08.21.554179 — immunology — Posted on 2023-08-22
1149 AI-based antibody discovery platform identifies novel, diverse and pharmacologically active therapeutic antibodies against multiple SARS-CoV-2 strains
Moldovan Loomis, C.; Lahlali, T.; Van Citters, D.; Sprague, M.; Neveu, G.; Somody, L.; Siska, C. C.; Deming, D.; Asakawa, A. J.; Amimeur, T.; Shaver, J. M.; Carbonelle, C.; Ketchem, R. R.; Alam, A.; Clark, R. H.
10.1101/2023.08.21.554197 — immunology — Posted on 2023-08-22
1151 Fatty acid desaturation and lipoxygenase pathways support trained immunity
Ferreira, A. V.; Alarcon-Barrera, J. C.; Dominguez-Andres, J.; Bulut, O.; Kilic, G.; Debisarun, P. A.; Röring, R. J.; Özhan, H. N.; Terschlüsen, E.; Ziogas, A.; Kostidis, S.; Mohammed, Y.; Matzaraki, V.; Renieris, G.; Giamarellos-Bourboulis, E. J.; Netea, M. G.; Giera, M.
10.1101/2023.08.22.554295 — immunology — Posted on 2023-08-22
1152 optiPRM: A targeted immunopeptidomics LC-MS workflow with ultra-high sensitivity for the detection of mutation-derived tumor neoepitopes from limited input material
Salek, M.; Forster, J. D.; Becker, J. P.; Meyer, M.; Charoentong, P.; Lyu, Y.; Lindner, K.; Lotsch, C.; Volkmar, M.; Momburg, F.; Poschke, I.; Frohling, S.; Schmitz, M.; Offringa, R.; Platten, M.; Jager, D.; Zornig, I.; Riemer, A. B.
10.1101/2023.08.22.554248 — immunology — Posted on 2023-08-23
1154 Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
Truex, N. L.; Mohapatra, S.; Melo, M.; Rodriguez, J.; Li, N.; Abraham, W.; Sementa, D.; Touti, F.; Keskin, D. B.; Wu, C. J.; Irvine, D. J.; Gomez-Bombarelli, R.; Pentelute, B. L.
10.1101/2023.08.22.554289 — immunology — Posted on 2023-08-23
1157 Cystic fibrosis systemic immune profile is associated with lung microbes and characterized by widespread alterations in the innate and adaptive immune compartments
Rossi, E.; Lausen Nielsen, M.; Friesgaard Obro, N.; Colque, C. A.; Nielsen, B. U.; Moller, R.; De Gier, C.; Hald, A.; Skov, M.; Pressler, T.; Molin, S.; Ostrowski, S. R.; Marquart, H. V.; Johansen, H. K.
10.1101/2023.08.23.553085 — immunology — Posted on 2023-08-23
1158 Quantitative analyses of T cell motion in tissue reveals factors driving T cell search in tissues
Torres, D. J.; Mrass, P.; Byrum, J.; Gonzales, A.; Martinez, D.; Juarez, M. E.; Thompson, E.; Vezys, V.; Cannon, J. L.
10.1101/2022.11.17.516891 — immunology — Posted on 2023-08-24
1159 Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans
Araujo, A.; Dekker, J. D.; Garrison, K.; Su, Z.; Rhee, C.; Hu, Z.; Lee, B.-K.; Osorio, D.; Lee, J.; Iyer, V. R.; Ehrlich, L. I. R.; Georgiou, G.; Ippolito, G. C.; Yi, S.; Tucker, H. O.
10.1101/310680 — immunology — Posted on 2023-08-24
1162 Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering
Li, F.; Roy, S.; Niculcea, J.; Gould, K.; Adams, E. J.; van der Merwe, P. A.; Choudhuri, K.
10.1101/2023.08.23.554524 — immunology — Posted on 2023-08-24
1163 Immune memory shapes human polyclonal antibody responses to H2N2 vaccination
Yang, Y. R.; Han, J.; Perrett, H. R.; Richey, S. T.; Jackson, A. M.; Rodriguez, A. J.; Gillespie, R. A.; O'Connell, S.; Raab, J. E.; Cominsky, L. Y.; Chopde, A.; Kanekiyo, M.; Houser, K. V.; Chen, G. L.; McDermott, A. B.; Andrews, S. F.; Ward, A. B.
10.1101/2023.08.23.554525 — immunology — Posted on 2023-08-24
1165 Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis
Maio, M.; Joly, M.; Vahlas, Z.; Barros, J.; Marin Franco, J. L.; Genoula, M.; Monard, S.; Vecchione, M. B.; Fuentes, F.; Gonzalez Polo, V.; Quiroga, M. F.; Vermeulen, M.; Argüello, R. J.; Inwentarz, S.; Musella, R.; Ciallella, L.; Gonzalez Montaner, P.; Palmero, D.; Lugo Villarino, G.; Sasiain, M. d. C.; Neyrolles, O.; Verollet, C.; Balboa, L.
10.1101/2023.04.03.535400 — immunology — Posted on 2023-08-24
1167 SARS-CoV-2 Nsp13 is a viral RHIM protein promoting cell death linked to Z-RNA sensing and ZBP1-RIPK3 signaling
Mishra, S.; Jain, D.; Dey, A. A.; Nagaraja, S.; Srivastava, M.; Khatun, O.; Balamurugan, K.; Anand, M.; Tripathi, S.; Ganji, M.; Kesavardhana, S.
10.1101/2023.08.23.554434 — immunology — Posted on 2023-08-24
1168 Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity
Moreno, A.; Manning, K.; Azeem, M. I.; Nooka, A. K.; Ellis, M.; Manalo, R. J.; Switchenko, J. M.; Wali, B.; Kaufman, J. L.; Hofmeister, C. C.; Joseph, N. S.; Lonial, S.; Dhodapkar, K. M.; Dhodapkar, M. V.; Suthar, M. S.
10.1101/2023.08.17.553767 — immunology — Posted on 2023-08-25
1169 Analysis of SARS-CoV-2 Omicron Neutralization Data up to 2022-01-28
Netzl, A.; Tureli, S.; LeGresley, E.; Mühlemann, B.; Wilks, S. H.; Smith, D. J.
10.1101/2021.12.31.474032 — immunology — Posted on 2023-08-25
1179 Inducible genetic ablation of Immt induces a lethal disruption of the MICOS complex
Rockfield, S. M.; Turnis, M. E.; Rodriguez-Enriquez, R.; Bathina, M.; Ng, S. K.; Pelletier, S.; Vogel, P.; Opferman, J. T.
10.1101/2023.08.22.554261 — physiology — Posted on 2023-08-23
1180 Disruption of Hepatic Mitochondrial Pyruvate and Amino Acid Metabolism Impairs Gluconeogenesis and Endurance Exercise Capacity in Mice
Martino, M. R.; Habibi, M.; Ferguson, D.; Brookheart, R. T.; Thyfault, J. P.; Meyer, G.; Lantier, L.; Hughey, C. C.; Finck, B. N.
10.1101/2023.08.22.554345 — physiology — Posted on 2023-08-23
1182 Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice
Yiew, N. K. H.; Ferguson, D.; Cho, K.; Deja, S.; Jarasvaraparn, C.; Jacome-Sosa, M.; Lutkewitte, A. J.; Mukherjee, S.; Fu, X.; Singer, J. M.; Patti, G. J.; Burgess, S. C.; Finck, B. N.
10.1101/2023.02.17.528992 — physiology — Posted on 2023-08-24
1183 Mitochondrial Pyruvate Carrier Inhibition Attenuates Hepatic Stellate Cell Activation and Liver Injury in a Mouse Model of Metabolic Dysfunction-associated Steatotic Liver Disease
Habibi, M.; Ferguson, D.; Eichler, S. J.; Chan, M. M.; LaPoint, A.; Shew, T. M.; He, M.; Lutkewitte, A. J.; Schilling, J. D.; Cho, K. Y.; Patti, G.; Finck, B. N.
10.1101/2023.02.13.528384 — physiology — Posted on 2023-08-25
1184 Nitric Oxide modulates spontaneous Ca2+ release and ventricular arrhythmias during β adrenergic signalling through S-nitrosylation of Calcium/Calmodulin dependent kinase II
Power, A. S.; Asamudo, E.; Worthington, L. P.; Alim, C. C.; Parackal, R.; Wallace, R. S.; Ebenebe, O. V.; Heller Brown, J.; Kohr, M. J.; Bers, D. M.; Erickson, J.
10.1101/2023.08.23.554546 — physiology — Posted on 2023-08-25
1188 Scalable querying of human cell atlases via a foundational model reveals commonalities across fibrosis-associated macrophages
Heimberg, G.; Kuo, T. C.; DePianto, D.; Heigl, T.; Diamant, N.; Salem, O.; Scalia, G.; Biancalani, T.; Rock, J.; Turley, S.; Bravo, H. C.; Kaminker, J.; Vander Heiden, J. A.; Regev, A.
10.1101/2023.07.18.549537 — bioinformatics — Posted on 2023-08-24
1189 Antibodies Expand the Scope of Angiotensin Receptor Pharmacology
Skiba, M. A.; Sterling, S. M.; Rawson, S.; Gilman, M. S. A.; Xu, H.; Nemeth, G. R.; Hurley, J. D.; Shen, P.; Staus, D. P.; Kim, J.; McMahon, C.; Lehtinen, M. K.; Wingler, L. M.; Kruse, A. C.
10.1101/2023.08.23.554128 — pharmacology and toxicology — Posted on 2023-08-24
1190 Benchmarking single-cell hashtag oligo demultiplexing methods
Howitt, G.; Feng, Y.; Tobar, L.; Vassiliadis, D.; Hickey, P.; Dawson, M. A.; Ranganathan, S.; Shanthikumar, S.; Neeland, M.; Maksimovic, J.; Oshlack, A.
10.1101/2022.12.20.521313 — bioinformatics — Posted on 2023-08-25
1192 MAVISp: Multi-layered Assessment of VarIants by Structure for proteins
Arnaudi, M.; Beltrame, L.; Degn, K.; Utichi, M.; Scrima, S.; Sanchez-Izquierdo, P.; Maselli, F.; Krzesinska, K.; Dorcakova, T.; Safer, J.; Meldgard, K.; Becker, P.; Pettenella, A.; Brockhoff, J. B.; Nielsen, A. D.; Vinhas, J.; Sackett, P. W.; Cava, C.; Rohlin, A.; Nilbert, M.; Iqbal, S.; Lambrughi, M.; Tiberti, M.; Papaleo, E.
10.1101/2022.10.22.513328 — bioinformatics — Posted on 2023-08-25
1193 A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ
Tao, A. J.; Jiang, J.; Gadbois, G. E.; Goyal, P.; Boyle, B. T.; Mumby, E. J.; Myers, S. A.; English, J. G.; Ferguson, F. M.
10.1101/2023.08.21.554211 — pharmacology and toxicology — Posted on 2023-08-25
1194 Nanoprojectile Secondary Ion Mass Spectrometry Enables Multiplexed Analysis of Individual Hepatic Extracellular Vesicles
Lee, S.; Verkhoturov, D. S.; Eller, M. J.; Verkhoturov, S. V.; Shaw, M.; Gwon, K.; Kim, Y.; Lucien, F.; Malhi, H.; Revzin, A.; Schweikert, E. A.
10.1101/2023.08.21.554053 — bioengineering — Posted on 2023-08-22
1195 Macrophage-targeted DNA methyltransferase inhibitor SGI-1027 decreases atherosclerosis in ApoE-null mice
Marquez-Sanchez, A. C.; Manzanares-Guzman, A.; Carriles-Jaimes, R.; Sanchez-Segura, L.; Colin-Castelan, D.; Kamen, D.; Koltsova, E. K.; Maritnez-Antonio, A.; Rodriguez-Rios, D.; Romo-Morales, G. d. C.; Lund, G.; Zaina, S.
10.1101/2023.08.22.554347 — pathology — Posted on 2023-08-22
1196 Engineering of a graphene oxide-based two-dimensional platform for immune activation and modulation
Despotopoulou, D.; Stylianou, M.; Arellano, L. M.; Kisby, T.; Lozano, N.; Kostarelos, K.
10.1101/2023.08.22.553542 — bioengineering — Posted on 2023-08-22
1197 Antisense Oligonucleotide Targeting Hepatic Serum Amyloid A Limits the Progression of Angiotensin II-Induced Abdominal Aortic Aneurysm Formation
Shridas, P.; Ji, A.; Trumbauer, A. C.; Noffsinger, V. P.; Meredith, L. W.; de Beer, F. C.; Mullick, A. E.; Webb, N. R.; Karounos, D. G.; Tannock, L. R.
10.1101/2023.08.22.554377 — pathology — Posted on 2023-08-23
1198 Assessment of bovine cortical bone fracture behavior using impact microindentation as a surrogate of fracture toughness
Vaidya, R.; Jahani, B.; Jin, J.; Broz, K.; Aboytes, D.; Pujari, B.; Krothapalli, S.; Baig, W. M.; Tang, S. Y.
10.1101/2023.08.07.552351 — bioengineering — Posted on 2023-08-22
1199 Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells
Cloarec-Ung, F.-M.; Beaulieu, J.; Suthananthan, A.; Lehnertz, B.; Sauvageau, G.; Sheppard, H. M.; Knapp, D. J.
10.1101/2023.05.26.542436 — bioengineering — Posted on 2023-08-22
1200 Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis
Rachagani, S.; Jean Wilson, E.; Sirpu Natesh, N.; Ghadermazi, P.; Pothuraju, R.; Shanmugam, M.; R. Prajapati, D.; Pandey, S.; T. Kaifi, J.; R. Dodam, J.; Bryan, J.; L. Lorson, C.; A. Watrelot, A.; M. Foster, J.; J. Mansel, T.; Joshua Chan, S. H.; Batra, S. K.; Subbiah, J.
10.1101/2023.08.23.554560 — pathology — Posted on 2023-08-24
1201 PRO-LDM: Protein Sequence Generation with Conditional Latent Diffusion Models
Jiang, Z.; Zhang, S.; Huang, R.; Mo, S.; Zhu, L.; Li, P.; Zhang, Z.; Chen, X.; Long, Y.; Xu, R.; Qing, R.
10.1101/2023.08.22.554145 — bioengineering — Posted on 2023-08-23
1207 Development and application of an uncapped mRNA platform
Zheng, X.; Liu, B.; Ni, P.; Cai, L.; Shi, X.; Ke, Z.; Zhang, S.; Hu, B.; Yang, B.; Xu, Y.; Long, W.; Fang, Z.; Wang, Y.; Zhang, W.; Xu, Y.; Wang, Z.; Pan, K.; Zhou, K.; Wang, H.; Geng, H.; Hu, H.; Liu, B.
10.1101/2022.06.05.494796 — bioengineering — Posted on 2023-08-24
1210 Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase
Casadevall, G.; Pierce, C. T.; Guan, B.; Iglesias-Fernandez, J.; Lim, H.-Y.; Greenberg, L. R.; Walsh, M. E.; Shi, K.; Gordon, W. R.; Aihara, H.; Evans, R. L.; Kazlauskas, R. J.; Osuna, S.
10.1101/2023.08.23.554512 — bioengineering — Posted on 2023-08-24
1211 Efficient and multiplexed tracking of single cells using whole-body PET/CT
Nguyen, H. T. M.; Das, N.; Wang, Y.; Ruvalcaba, C.; Mehadji, B.; Roncali, E.; Chan, C. K. F.; Pratx, G. J.
10.1101/2023.08.23.554536 — bioengineering — Posted on 2023-08-24
1212 Rationally designed multimeric nanovaccines using icosahedral DNA origami for molecularly controlled display of SARS-CoV-2 receptor binding domain
Feng, Q.; Cheng, K.; Zhang, L.; Gao, X.; Liang, J.; Liu, G.; Ma, N.; Xu, C.; Tang, M.; Chen, L.; Wang, X.; Ma, X.; Zou, J.; Shi, Q.; Du, P.; Wang, Q.; Nie, G.; Zhao, X.
10.1101/2023.08.24.554561 — bioengineering — Posted on 2023-08-24
1213 Systematic evaluation of protein-small molecule hybrids on the yeast surface
Huang, M.; Rueda-Garcia, M.; Harthorn, A.; Hackel, B. J.; Van Deventer, J. A.
10.1101/2023.05.12.540568 — bioengineering — Posted on 2023-08-24
1215 Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 ℃
Hansen, T.; Lee, J. C.; Reicher, N.; Ovadia, G.; Guo, S.; Guo, W.; Liu, J.; Braslavsky, I.; Rudich, Y.; Davies, P. L.
10.1101/2023.08.03.551873 — biochemistry — Posted on 2023-08-22
1217 The resting state of the human T-cell receptor
Notti, R. Q.; Yi, F.; Heissel, S.; Molina, H.; Klebanoff, C. A.; Walz, T.
10.1101/2023.08.22.554360 — biochemistry — Posted on 2023-08-22
1219 Microbial strong organic ligand production is tightly coupled to iron in hydrothermal plumes
Hoffman, C. L.; Monreal, P. J.; Albers, J. B.; Lough, A. J. M.; Santoro, A. E.; Mellett, T.; Buck, K. N.; Tagliabue, A.; Lohan, M. C.; Resing, J. A.; Bundy, R. M.
10.1101/2023.01.05.522639 — biochemistry — Posted on 2023-08-22
1222 De novo design of buttressed loops for sculpting protein functions
Jiang, H.; Jude, K. M.; Wu, K.; Fallas, J.; Ueda, G.; Brunette, T.; Hicks, D.; Pyles, H.; Yang, A.; Carter, L.; Lamb, M.; Li, X.; Levine, P. M.; Stewart, L. J.; Garcia, K. C.; Baker, D.
10.1101/2023.08.22.554384 — biochemistry — Posted on 2023-08-23
1223 An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
Kaya, P.; Schaffner-Reckinger, E.; Manoharan, G. B.; Vukic, V.; Kiriazis, A.; Ledda, M.; Burgos, M.; Pavic, K.; Gaigneaux, A.; Glaab, E.; Abankwa, D. K.
10.1101/2023.08.23.554263 — biochemistry — Posted on 2023-08-23
1226 Spatial lipidomics of fresh-frozen spines
Bender, K. J.; Wang, Y.; Zhai, C. Y.; Saenz, Z.; Wang, A.; Neumann, E. K.
10.1101/2023.08.23.554488 — biochemistry — Posted on 2023-08-24
1227 iATPSnFR2: a high dynamic range fluorescent sensor for monitoring intracellular ATP
Marvin, J. S.; Kokotos, A. C.; Kumar, M.; Pulido, C.; Tkachuk, A. N.; Yao, J. S.; Brown, T. A.; Ryan, T. A.
10.1101/2023.08.24.554624 — biochemistry — Posted on 2023-08-24
1230 Biophysical analysis reveals autophosphorylation as an important negative regulator of LRRK2 dimerization
Guaitoli, G.; Zhang, X.; Saitta, F.; Miglionico, P.; Silbermann, L. M.; Ho, F. Y.; von Zweydorf, F.; Signorelli, M.; Tych, K.; Fessas, D.; Raimondi, F.; Kortholt, A.; Gloeckner, C. J.
10.1101/2023.08.11.549911 — biochemistry — Posted on 2023-08-24
1231 Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase
Blomgren, L. K. M.; Huber, M.; Mackinnon, S. R.; Burer, C.; Basle, A.; Froese, D. S.; Yue, W. W.; McCorvie, T. J.
10.1101/2023.08.02.551630 — biochemistry — Posted on 2023-08-24
1232 Structure of Orthoreovirus RNA Chaperone σNS, a Component of Viral Replication Factories
Zhao, B.; Hu, L.; Kuandal, S.; Neetu, N.; Lee, C.; Somoulay, X.; Sankaran, B.; Taylor, G. M.; Dermody, T. S.; Prasad, B. V. V.
10.1101/2023.07.31.551319 — biochemistry — Posted on 2023-08-24
1235 A Spatiotemporal Molecular Atlas of the Ovulating Mouse Ovary
Mantri, M.; Zhang, H. H.; Spanos, E.; Ren, Y. A.; De Vlaminck, I.
10.1101/2023.08.21.554210 — genomics — Posted on 2023-08-22
1236 Transposable element expression with variation in sex chromosome number supports a toxic Y effect on human longevity
Teoli, J.; Fablet, M.; Bardel, C.; Necsulea, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2023-08-22
1237 A Spatiotemporal Molecular Atlas of the Ovulating Mouse Ovary
Mantri, M.; Zhang, H. H.; Spanos, E.; Ren, Y. A.; De Vlaminck, I.
10.1101/2023.08.21.554210 — genomics — Posted on 2023-08-22
1238 Allelic bias when performing in-solution enrichment of ancient human DNA
Davidson, R.; Williams, M. P.; Roca-Rada, X.; Kassadjikova, K.; Tobler, R.; Fehren-Schmitz, L.; Llamas, B.
10.1101/2023.07.04.547445 — genomics — Posted on 2023-08-22
1239 Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles
Leal, J. L.; Milesi, P.; Hodkova, E.; Zhou, Q.; James, J.; Eklund, D. M.; Pyhajarvi, T.; Salojarvi, J.; Lascoux, M.
10.1101/2023.08.23.553805 — genomics — Posted on 2023-08-23
1240 Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles
Leal, J. L.; Milesi, P.; Hodkova, E.; Zhou, Q.; James, J.; Eklund, D. M.; Pyhajarvi, T.; Salojarvi, J.; Lascoux, M.
10.1101/2023.08.23.553805 — genomics — Posted on 2023-08-23
1241 Metastable Intermediates Identified in Epithelial to Mesenchymal Transition are Regulated by G-Quadruplex DNA Structures
King, J. J.; Evans, C. W.; Kadolsky, U. D.; Norret, M.; Iqbal, M.; Merce, C.; Bhatia, S.; Gregory, P. A.; Thompson, E. W.; Saxena, A.; Swaminathan Iyer, K.; Smith, N. M.
10.1101/2023.08.21.554220 — genomics — Posted on 2023-08-23
1243 A chromosome-scale assembly for dAnjou pear
Yocca, A. E.; Akinyuwa, M.; Bailey, N.; Cliver, B.; Estes, H.; Guillemette, A.; Hasannin, O.; Hutchison, J.; Jenkins, W.; Kaur, I.; Rahul Khanna, R.; Loftin, M.; Lopes, L.; Moore-Pollard, E.; Olofintila, O.; Oluwaseye Oyebode, G.; Patel, J.; Thapa, P.; Waldinger, M.; Zhang, J.; Zhang, Q.; Goertzen, L. R.; Carey, S. B.; Hargarten, H.; Mattheis, J.; Zhang, H.; Jones, T.; Boston, L.; Grimwood, J.; Ficklin, S.; Honaas, L.; Harkess, A. E.
10.1101/2023.08.22.554305 — genomics — Posted on 2023-08-23
1245 Transcription-Replication Conflict Shapes DNA Break Dynamics
Ionasz, V.; Corazzi, L.; Andrejev, S.; Vouzas, A.; Wang, L.-C.; Giaisi, M.; Di Muzio, G.; Ding, B.; Fu, J.; Abdelbaki, A.; Gilbert, D. M.; Wei, P.-C.
10.1101/2023.08.22.554340 — genomics — Posted on 2023-08-23
1246 Genome-wide assays to characterize rAAV integration into human genomic DNA in vivo
Prout, J.; Von Stetina, J.; Cerqueira, G.; Chasse, M.; Chen, H.-M.; Pla, A.; Resendes, R.; Sookiassian, D.; Tazearslan, C.; Wright, J.; Thompson, J. F.
10.1101/2023.08.22.554338 — genomics — Posted on 2023-08-23
1247 The genome of a globally invasive passerine, the common myna (Acridotheres tristis)
Stuart, K. C.; Johnson, R. N.; Major, R.; Atsawawaranunt, K.; Ewart, K. M.; Rollins, L. A.; Santure, A. W.; Whibley, A.
10.1101/2023.08.22.554353 — genomics — Posted on 2023-08-23
1248 Harnessing the pangenome for genomic surveillance: Salmonella enterica serotype Typhi as a paradigm
Penil-Celis, A.; Tagg, K. A.; Webb, H. E.; Redondo-Salvo, S.; Watkins, L. F.; Vielva, L.; Griffin, C.; Kim, J. Y.; Folster, J. P.; Garcillan-Barcia, M. P.; de la Cruz, F.
10.1101/2023.08.23.554479 — genomics — Posted on 2023-08-23
1249 CRISPR-based Genome Editing of a Diurnal Rodent, Nile Grass Rat (Arvicanthis niloticus)
Xie, H.; Linning-Duffy, K.; Demireva, E. Y.; Toh, H.; Abolibdeh, B.; Shi, J.; Zhou, B.; Iwase, S.; Yan, L.
10.1101/2023.08.23.553600 — genomics — Posted on 2023-08-23
1250 Comparison of gene clustering criteria reveals intrinsic uncertainty in pangenome analyses
Manzano-Morales, S.; Liu, Y.; Gonzalez-Bodi, S.; Huerta-Cepas, J.; Iranzo, J.
10.1101/2022.09.25.509376 — genomics — Posted on 2023-08-24
1251 Molecular and functional characterization of the Drosophila melanogaster conserved smORFome
Bosch, J. A.; Keith, N.; Escobedo, F.; Fisher, W. W.; LaGraff, J. T.; Rabasco, J.; Wan, K.; Weiszmann, R.; Hu, Y.; Kondo, S.; Brown, J. B.; Perrimon, N.; Celniker, S. E.
10.1101/2022.04.24.489283 — genomics — Posted on 2023-08-24
1252 Genetic and Structural Basis of Colistin Resistance in Klebsiella pneumoniae: Unraveling the Molecular Mechanisms
Alousi, S.; Saad, J.; Panossian, B.; Makhlouf, R.; Al Khoury, C.; Rahy, K.; Thoumi, S.; ARAJ, G. F.; Khnayzer, R.; Tokajian, S.
10.1101/2023.08.23.554495 — genomics — Posted on 2023-08-24
1253 The genome of the Wollemi pine, a critically endangered living fossil unchanged since the Cretaceous, reveals extensive ancient transposon activity.
Stevenson, D. W.; Ramakrishnan, S.; Alves, C. d. S.; Coelho, L. A.; Kramer, M.; Goodwin, S.; Ramos, O. M.; Eshel, G.; Sondervan, V. M.; Frangos, S.; Zumajo-Cardona, C.; Jenike, K.; Ou, S.; Wang, X.; Lee, Y. P.; Loke, S.; Rossetto, M.; McPherson, H.; Nigris, S.; Moschin, S.; Little, D. P.; Katari, M. S.; Varala, K.; Kolokotronis, S.-O.; Ambrose, B.; Croft, L. J.; Coruzzi, G. M.; Schatz, M.; McCombie, W. R.; Martienssen, R. A.
10.1101/2023.08.24.554647 — genomics — Posted on 2023-08-24
1254 First clinical validation of whole genome screening on standard trophectoderm biopsies of preimplantation embryos
Xia, Y.; Chertman, W.; Chandramohan, D.; Katz, M.; Bechor, E.; Podgursky, B.; Hoxie, M.; Zhang, Q.; Kang, J.; Blue, E.; Chen, J.; Schleede, J.; Slotnick, N.; Du, X.; Kort, J.; Boostanfar, R.; Urcia, E.; Behr, B.; Siddiqui, N.
10.1101/2022.04.14.488421 — genomics — Posted on 2023-08-24
1255 Genome-wide assays to characterize rAAV integration into human genomic DNA in vivo
Prout, J.; Von Stetina, J.; Cerqueira, G.; Chasse, M.; Chen, H.-M.; Pla, A.; Resendes, R.; Sookiasian, D.; Tazearslan, C.; Wright, J.; Thompson, J. F.
10.1101/2023.08.22.554338 — genomics — Posted on 2023-08-24
1258 Striatal dopamine release reflects a domain-general prediction error
Costa, K. M.; Raheja, N.; Mirani, J.; Sercander, C.; Schoenbaum, G.
10.1101/2023.08.19.553959 — neuroscience — Posted on 2023-08-25
1260 Methods and techniques enabling multi-kilobase long-range genomic rewrite/replace editing
Piggott, C. A.; Tjang, L. V.; Chen, S.; Tatu, U.; Hirou, H.; Jaroszewska, A.; McIntyre, E.; Chen, J.; Faybishenko, J. V.; Gavan, R.; Hackley, C.
10.1101/2023.08.05.551844 — genetics — Posted on 2023-08-22
1261 Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and non-human primates
Longlong, Z.; Wang, H.; Xun, M.; Tang, H.; Wang, J.; Lv, J.; Zhu, B.; Chen, Y.; Wang, D.; Hu, S.; Gao, Z.; Liu, J.; Chen, Z.-Y.; Chen, B.; Li, H.; Shu, Y.
10.1101/2023.08.22.554252 — genetics — Posted on 2023-08-23
1263 Admixture as a source for HLA variation in Neolithic European farming communities
da Silva, N. A.; Ozer, O.; Haller, M.; Chen, Y.-R.; Kolbe, D.; Schade-Linding, S.; Wahl, J.; Berszin, C.; Francken, M.; Gorner, I.; Schierhold, K.; Pechtl, J.; Grupe, G.; Rinne, C.; Muller, J.; Lenz, T. L.; Nebel, A.; Krause-Kyora, B.
10.1101/2023.08.23.554285 — genetics — Posted on 2023-08-23
1265 The influence of prenatal alcohol exposure and maternal diet on offspring DNA methylation: a cross-species study
Bestry, M.; Larcombe, A. N.; Kresoje, N.; Chivers, E. K.; Bakker, C.; Fitzpatrick, J. P.; Elliott, E. J.; Craig, J. M.; Muggli, E.; Halliday, J.; Hutchinson, D.; Buckberry, S.; Lister, R.; Symons, M.; Martino, D.
10.1101/2023.06.15.544516 — genetics — Posted on 2023-08-24
1266 Copy number variation and population-specific immune genes in the model vertebrate zebrafish
Schäfer, Y.; Palitzsch, K.; Leptin, M.; Whiteley, A. R.; Wiehe, T.; Suurväli, J.
10.1101/2023.08.23.554498 — genetics — Posted on 2023-08-24
1267 Functional Plasticity in Chromosome-Microtubule Coupling on the Evolutionary Time Scale
Sankaranarayanan, S. R.; Polisetty, S. D.; Das, K.; Dumbrepatil, A.; Medina-Pritchard, B.; Singleton, M.; Jeyaprakash, A. A.; Sanyal, K.
10.1101/2022.02.25.481917 — genetics — Posted on 2023-08-25
1272 Extreme high-elevation mammal surveys reveal unexpectedly high upper range limits of Andean mice
Storz, J.; Quiroga-Carmona, M.; Liphardt, S.; Bautista, N. M.; Opazo, J. C.; Rico, A.; Salazar-Bravo, J.; Good, J.; D'Elia, G.
10.1101/2023.08.22.554215 — evolutionary biology — Posted on 2023-08-23
1277 Rapid turnover of centromeric DNA reveals signatures of genetic conflict in Drosophila
Courret, C.; Hemmer, L.; Wei, X.; Patel, P. D.; Santinello, B.; Geng, X.; Chang, C.-H.; Mellone, B.; Larracuente, A. M.
10.1101/2023.08.22.554357 — evolutionary biology — Posted on 2023-08-23
1278 Intra- and interspecific variations in genome sizes of Agaricia corals from Curacao
Ranises, D. M. L.; Gonzalez, M. J. V.; Tawfeeq, M. M.; Gaudray, F. R.; Malay, M. C. D.; Vermeij, M.; Flot, J.-F.
10.1101/2023.08.23.554453 — evolutionary biology — Posted on 2023-08-23
1279 A Lethal Genetic Incompatibility between Naturally Hybridizing Species in Mitochondrial Complex I
Moran, B. M.; Payne, C. Y.; Powell, D. L.; Iverson, E. N.; Donny, A. E.; Banerjee, S. M.; Langdon, Q. K.; Gunn, T. R.; Rodriguez-Soto, R. A.; Madero, A.; Baczenas, J. J.; Kleczko, K. M.; Liu, F.; Matney, R.; Singhal, K.; Leib, R. D.; Hernandez-Perez, O.; Corbett-Detig, R.; Frydman, J.; Gifford, C.; Schartl, M.; Havird, J. C.; Schumer, M.
10.1101/2021.07.13.452279 — evolutionary biology — Posted on 2023-08-24
1283 African bush pigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival
Balboa, R. F.; Bertola, L. D.; Bruniche-Olsen, A.; Rasmussen, M. S.; Liu, X.; Besnard, G.; Salmona, J.; Santander, C. G.; He, S.; Zinner, D.; Pedrono, M.; Muwanika, V.; Masembe, C.; Schubert, M.; Kuja, J.; Quinn, L.; Garcia-Erill, G.; Rakotoarivony, R.; Henrique, M.; Lin, L.; Wang, X.; Heaton, M. P.; Smith, T. P. L.; Hanghoj, K.; Sinding, M.-H. S.; Atickem, A.; Chikhi, L.; Roos, C.; Gaubert, P.; Siegismund, H. R.; Moltke, I.; Albrechtsen, A.; Heller, R.
10.1101/2023.08.23.553838 — evolutionary biology — Posted on 2023-08-24
1284 Genetic differentiation and host specialization among OsHV-1 infecting two oyster species in France
Pelletier, C.; Chevignon, G.; Faury, N.; Arzul, I.; Garcia, C.; Chollet, B.; Renault, T.; Morga, B.; Jacquot, M.
10.1101/2023.08.23.554398 — evolutionary biology — Posted on 2023-08-24
1287 Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations
Lou, J.; Liang, W.; Cao, L.; Zhao, S.; Chen, Z.; Chan, R. W.; Cheung, P. P. H.; Zheng, H.; Liu, C.; Li, Q.; Chong, M.; Zhang, Y.; Yeoh, E.-k.; Chan, P. K.; Zee, B.; Mok, C. K.-P.; Wang, M. H.
10.1101/2023.08.23.554557 — evolutionary biology — Posted on 2023-08-24
1291 Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo
Ichimura, T.; Kakizuka, T.; Sato, Y.; Itano, K.; Seiriki, K.; Hashimoto, H.; Itoga, H.; Onami, S.; Nagai, T.
10.1101/2023.08.21.553997 — developmental biology — Posted on 2023-08-22
1292 Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans
Kohlbrenner, T.; Berger, S.; Aegerter-Wilmsen, T.; Laranjeira, A.; deMello, A.; Hajnal, A.
10.1101/2023.08.22.554140 — developmental biology — Posted on 2023-08-22
1293 Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds
Panara, V.; Yu, H.; Peng, D.; Staxang, K.; Hodik, M.; Filipek-Gorniok, B.; Kazenwadel, J.; Skoczylas, R.; Mason, E. A.; Allalou, A.; Harvey, N. L.; Haitina, T.; Hogan, B.; Koltowska, K.
10.1101/2023.08.21.550483 — developmental biology — Posted on 2023-08-22
1294 Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease
Smits, J.; Cunha, D. L.; Qu, J.; Owen, N.; Latta, L.; Szentmary, N.; Seitz, B.; Roux, L. N.; Moosajee, M.; Aberdam, D.; van Heeringen, S. J.; Zhou, H.
10.1101/2022.07.13.499857 — developmental biology — Posted on 2023-08-23
1296 Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition
Lozovska, A.; Nóvoa, A.; Kuo, Y.-Y.; Jurberg, A. D.; Martins, G. G.; Hadjantonakis, A.-K.; Mallo, M.
10.1101/2023.08.22.554351 — developmental biology — Posted on 2023-08-23
1297 Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.
Russell, N.; Burra, K.; Shah, R.; Bottasso-Arias, N.; Mohanakrishnan, M.; Snowball, J.; Ediga, H.; Madala, S. K.; Sinner, D. I.
10.1101/2023.01.10.523309 — developmental biology — Posted on 2023-08-24
1298 FOXL2 interaction with different binding partners regulates the dynamics of ovarian development
Migale, R.; Neumann, M.; Mitter, R.; Rafiee, M.-R.; Wood, S.; Olsen, J.; Lovell-Badge, R.
10.1101/2023.04.14.536403 — developmental biology — Posted on 2023-08-24
1302 SIN-3 transcriptional coregulator maintains mitochondrial homeostasis and polyamine flux
Giovannetti, M.; Fabrizio, P.; Nicolle, O.; Bedet, C.; Rodriguez-Palero, M.; Michaux, G.; Artal-Sanz, M.; Witting, M.; Palladino, F.
10.1101/2023.08.07.552272 — developmental biology — Posted on 2023-08-24
1303 Primate-expressed EPIREGULIN promotes basal progenitor proliferation in the developing neocortex
Cubillos, P.; Ditzer, N.; Kolodziejczyk, A.; Schwenk, G.; Hoffmann, J.; Schütze, T. M.; Derihaci, R. P.; Birdir, C.; Köllner, J. E. M.; Petzold, A.; Sarov, M.; Martin, U.; Long, K. R.; Wimberger, P.; Albert, M.
10.1101/2023.08.23.554446 — developmental biology — Posted on 2023-08-24
1306 Improved Estimation of Bird Abundance and Energy Consumption by Combining Point and Transect Observations
Thron, C.; Santillan, V.; Quitian, M.; Neuschulz, E. L.; Schleuning, M.; Boehning-Gaese, K.; Brothers, A.; Bolagay, M. J. A.; Alvarez, O.
10.1101/2023.08.21.554181 — ecology — Posted on 2023-08-22
1309 Controlling biases in targeted plant removal experiments
Monteux, S.; Blume-Werry, G.; Gavazov, K.; Kirchhoff, L. K.; Krab, E. J.; Lett, S.; Pedersen, E. P.; Vaisanen, M.
10.1101/2023.08.22.554120 — ecology — Posted on 2023-08-22
1310 Turning Ecology Against Pesticide Resistance: Exploiting Competition in Pest Populations Through Pesticide Use
Guariento, R. D.; Almeida-Gomes, M.; Oliveira-Santos, L. G. R.; Pires, A. P. F.; Roque, F. d. O.
10.1101/2023.06.16.545263 — ecology — Posted on 2023-08-22
1311 Turning Ecology Against Pesticide Resistance: Exploiting Competition in Pest Populations Through Pesticide Use
Guariento, R. D.; Almeida-Gomes, M.; Oliveira-Santos, L. G. R.; Pires, A. P. F.; Roque, F. d. O.
10.1101/2023.06.16.545263 — ecology — Posted on 2023-08-22
1316 Understanding spatiotemporal effects of food supplementation on host-parasite interactions using community-based science
Knutie, S. A.; Bahouth, R.; Bertone, M. A.; Webb, C.; Mehta, M.; Nahom, M.; Barta, R. M.; Ghai, S.; Love, A. C.; Horan, S.; Soldo, A.; Cochrane, E.; Bartholomew, J.; Cowan, E.; Bjerke, H.; Balenger, S. L.; Butler, M. W.; Cornell, A.; Kennedy, A. C.; Rolland, V.; Schultz, E. M.; Stanback, M.; Taff, C. C.; Albery, G. F.
10.1101/2022.06.02.494595 — ecology — Posted on 2023-08-23
1317 Understanding spatiotemporal effects of food supplementation on host-parasite interactions using community-based science
Knutie, S. A.; Bahouth, R.; Bertone, M. A.; Webb, C.; Mehta, M.; Nahom, M.; Barta, R. M.; Ghai, S.; Love, A. C.; Horan, S.; Soldo, A.; Cochrane, E.; Bartholomew, J.; Cowan, E.; Bjerke, H.; Balenger, S. L.; Butler, M. W.; Cornell, A.; Kennedy, A. C.; Rolland, V.; Schultz, E. M.; Stanback, M.; Taff, C. C.; Albery, G. F.
10.1101/2022.06.02.494595 — ecology — Posted on 2023-08-23
1319 The effects of human population density on trophic interactions are contingent upon latitude
Hernandez-Aguero, J. A.; Ruiz-Tapiador, I.; Garibaldi, L. A.; Kozlov, M. V.; Mantyla, E.; Nacif, M. E.; Salinas, N.; Cayuela, L.
10.1101/2023.08.22.554272 — ecology — Posted on 2023-08-23
1320 Integrating habitat suitability modeling with gene flow improves delineation of landscape connections among African savanna elephants
de Flamingh, A.; Alexander, N.; Perrin-Stowe, T.; Donnelly, C.; Guldemondt, R.; Schooley, R.; van Aarde, R.; Roca, A.
10.1101/2023.08.22.554325 — ecology — Posted on 2023-08-23
1323 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats
Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.
10.1101/2023.08.10.552777 — ecology — Posted on 2023-08-24
1324 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats
Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.
10.1101/2023.08.10.552777 — ecology — Posted on 2023-08-24
1328 Drivers of species knowledge across the Tree of Life
Mammola, S.; Adamo, M.; Antic, D.; Calevo, J.; Cancellario, T.; Cardoso, P.; Chamberlain, D.; Chialva, M.; Durucan, F.; Fontaneto, D.; Goncalves, D.; Martinez, A.; Santini, L.; Rubio-Lopez, I.; Sousa, R.; Villegas-Rios, D.; Verdes, A.; Correia, R. A.
10.1101/2023.03.27.534304 — ecology — Posted on 2023-08-24
1329 Drivers of species knowledge across the Tree of Life
Mammola, S.; Adamo, M.; Antic, D.; Calevo, J.; Cancellario, T.; Cardoso, P.; Chamberlain, D.; Chialva, M.; Durucan, F.; Fontaneto, D.; Goncalves, D.; Martinez, A.; Santini, L.; Rubio-Lopez, I.; Sousa, R.; Villegas-Rios, D.; Verdes, A.; Correia, R. A.
10.1101/2023.03.27.534304 — ecology — Posted on 2023-08-24
1332 The demographic history of the wild crop relative Brachypodium distachyon is shaped by distinct past and present ecological niches.
Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.
10.1101/2023.06.01.543285 — ecology — Posted on 2023-08-24
1333 The demographic history of the wild crop relative Brachypodium distachyon is shaped by distinct past and present ecological niches.
Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.
10.1101/2023.06.01.543285 — ecology — Posted on 2023-08-24
1334 Herptile gut microbiomes: a natural system to study multi-kingdom interactions between filamentous fungi and bacteria
Vargas-Gastelum, L. B.; Romer, A. S.; Alexander, N. R.; Ghotbi, M.; Moe, K. C.; McPhail, K. L.; Neuhaus, G. F.; Shadmani, L.; Spatafora, J. W.; Stajich, J. E.; Tabima, J. F.; Walker, D.
10.1101/2023.08.23.554450 — ecology — Posted on 2023-08-25
1335 Protection of β2GPI Deficient Mice from Thrombosis Reflects a Defect in PAR3-facilitated Platelet Activation
Kulkarni, P. P.; Alluri, R. K.; Godwin, M.; Forbes, G. L.; Merkulova, A.; Vijay, A.; Palihati, M.; Kundu, S.; Shim, Y. J.; Schmaier, A. H.; Holinstat, M.; Cameron, S. J.; McCrae, K. R.
10.1101/2023.08.23.554547 — cell biology — Posted on 2023-08-25
1336 Reorganization of Septin structures regulates early myogenesis
Knaus, P.; Ugorets, V.; Mendez, P.; Zagrebin, D.; Russo, G.; Kerkhoff, Y.; Herpelinck, T.; Kotsaris, G.; Jatzlau, J.; Stricker, S.
10.1101/2023.08.24.554594 — cell biology — Posted on 2023-08-25
1337 Ultra-high density electrodes improve detection, yield, and cell type specificity of brain recordings
Ye, Z.; Shelton, A. M.; Shaker, J. R.; Boussard, J. M.; Colonell, J.; Minavi, S.; Chen, S.; Windolf, C.; Hurwitz, C.; Namima, T.; Pedraja, F.; Weiss, S.; Raducanu, B.; Ness, T.; Einevoll, G. T.; Laurent, G.; Sawtell, N. B.; Bair, W.; Pasupathy, A.; Mora-Lopez, C.; Dutta, B.; Paninski, L.; Siegle, J. H.; Koch, C.; Olsen, S. R.; Harris, T. D.; Steinmetz, N. A.
10.1101/2023.08.23.554527 — neuroscience — Posted on 2023-08-25
1338 Transcriptomic analysis identifies synapse-enriched lncRNAs required for glutamatergic synapse development and fear memory consolidation.
Samaddar, S.; Srinivasan, B.; Garg, K.; Raj, N.; Sultana, S.; Mukherjee, U.; Banerjee, D.; Liau, W.-S.; Palakodeti, D.; Bredy, T. W.; Banerjee, S.
10.1101/2023.07.14.549055 — neuroscience — Posted on 2023-08-25
1340 Using synchronized brain rhythms to bias memory-guided decisions
Stout, J. J.; George, A. E.; Kim, S.; Hallock, H. L.; Griffin, A. L.
10.1101/2023.04.02.535279 — neuroscience — Posted on 2023-08-24
1342 Effort Foraging Task reveals positive correlation between individual differences in the cost of cognitive and physical effort in humans
Bustamante, L. A.; Oshinowo, T.; Lee, J. R.; Tong, E.; Burton, A. R.; Shenhav, A. S.; Cohen, J. D.; Daw, N. D.
10.1101/2022.11.21.517394 — neuroscience — Posted on 2023-08-24
1344 Two functionally distinct HEATR5 protein complexes are defined by fast-evolving co-factors in yeast
Marmorale, L. J.; Jin, H.; Reidy, T. G.; Palomino-Alonso, B.; Zysnarski, C.; Jordan-Javed, F.; Lahiri, S.; Duncan, M. C.
10.1101/2023.08.24.554671 — cell biology — Posted on 2023-08-24
1345 Separating cognitive and motor processes in the behaving mouse
Hasnain, M. A.; Birnbaum, J. E.; Nunez, J. L. U.; Hartman, E.; Chandrasekaran, C.; Economo, M. N.
10.1101/2023.08.23.554474 — neuroscience — Posted on 2023-08-24
1350 Neuromuscular Basis of Drosophila larval rolling escape behavior
Cooney, P. C.; Huang, Y.; Li, W.; Perera, D. M.; Hormigo, R.; Tabachnik, T.; Godage, I.; Hillman, E. M. C.; Grueber, W. B.; Zarin, A. A.
10.1101/2023.02.01.526733 — neuroscience — Posted on 2023-08-24
1352 Ultra-high density electrodes improve detection, yield, and cell type specificity of brain recordings
Ye, Z.; Shelton, A. M.; Shaker, J. R.; Boussard, J. M.; Colonell, J.; Minavi, S.; Chen, S.; Windolf, C.; Hurwitz, C.; Namima, T.; Pedraja, F.; Weiss, S.; Raducanu, B.; Ness, T.; Einevoll, G. T.; Laurent, G.; Sawtell, N. B.; Bair, W.; Pasupathy, A.; Mora-Lopez, C.; Dutta, B.; Paninski, L.; Siegle, J. H.; Koch, C.; Olsen, S. r.; Harris, T. D.; Steinmetz, N. A.
10.1101/2023.08.23.554527 — neuroscience — Posted on 2023-08-24
1354 Comparative neuroimaging of sex differences in human and mouse brain anatomy
Guma, E.; Beauchamp, A.; Liu, S.; Levitis, E.; Ellegood, J.; Pham, L.; Mars, R. B.; Raznahan, A.; Lerch, J. P.
10.1101/2023.08.23.554334 — neuroscience — Posted on 2023-08-24
1355 Enhanced Aversive Signals During Classical Conditioning in Dopamine Axons in Medial Prefrontal Cortex
Abe, K.; Kambe, Y.; Majima, K.; Hu, Z.; Ohtake, M.; Momennezhad, A.; Izumi, H.; Tanaka, T.; Matunis, A.; Stacy, E.; Itokazu, T.; Sato, T. R.; Sato, T. K.
10.1101/2023.08.23.554475 — neuroscience — Posted on 2023-08-24
1360 Using network control theory to study the dynamics of the structural connectome
Parkes, L.; Kim, J. Z.; Stiso, J.; Brynildsen, J. K.; Cieslak, M.; Covitz, S.; Gur, R. E.; Gur, R. C.; Pasqualetti, F.; Shinohara, R. T.; Zhou, D.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2023.08.23.554519 — neuroscience — Posted on 2023-08-24
1362 Off-targets of BRAF inhibitors disrupt endothelial signaling and differentially affect vascular barrier function
Bromberger, S.; Zadorozhna, Y.; Ressler, J. M.; Holzner, S.; Nawrocki, A.; Zila, N.; Springer, A.; Larsen, M. R.; Schossleitner, K.
10.1101/2023.08.24.554606 — cell biology — Posted on 2023-08-24
1363 ACD15, ACD21, and SLN regulate accumulation and mobility of MBD6 to silence genes and transposable elements.
Boone, B. A.; Ichino, L.; Wang, S.; Gardiner, J.; Yun, J.; Jami-Alahmadi, Y.; Sha, J.; Mendoza, C. P.; Steelman, B. J.; Aardenne, A. v.; Kira-Lucas, S.; Trentchev, I.; Wohlschlegel, J.; Jacobsen, S. E.
10.1101/2023.08.23.554494 — cell biology — Posted on 2023-08-24
1366 Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.
Santos, C. d.; Shrestha, S.; Cottam, M. A.; Perkins, G.; Lev-Ram, V.; Roy, B.; Acree, C.; Kim, K.-Y.; Deerinck, T.; Cutler, M.; Dean, D.; Cartailler, J. P.; MacDonald, P. E.; Hetzer, M. W.; Ellisman, M. H.; Arrojo e Drigo, R.
10.1101/2023.08.23.554369 — cell biology — Posted on 2023-08-24
1368 Polybacterial intracellular coinfection of epithelial stem cells in periodontitis
Easter, Q. T.; Matuck, B. F.; Stark, G. B.; Worth, C. L.; Predeus, A. V.; Fremin, B.; Huynh, K. T.; Ranganathan, V.; Pereira, D.; Weaver, T.; Miller, K.; Perez, P.; Hasuike, A.; Chen, Z.; Bush, M.; Qu, X.; Warner, B. M.; Lee, J.; Wallet, S. M.; Sequeira, I.; Tyc, K. M.; Liu, J.; Ko, K. I.; Teichmann, S. A.; Byrd, K. M.
10.1101/2023.08.23.554343 — cell biology — Posted on 2023-08-24
1370 D--hydroxybutyrate stabilizes the hippocampal CA3-CA1 circuit during acute insulin resistance.
Kula, B.; Antal, B.; Weistuch, C.; Gackiere, F.; Barre, A.; Velado, V.; Hubbard, J. M.; Kukley, M.; Mujica-Parodi, L. R.; Smith, N. A.
10.1101/2023.08.23.554428 — neuroscience — Posted on 2023-08-24
1374 Age-dependent extinction and the neutral theory of biodiversity
Saulsbury, J. G.; Parins-Fukuchi, C. T.; Wilson, C. J.; Reitan, T.; Liow, L. H.
10.1101/2023.08.23.554417 — paleontology — Posted on 2023-08-24
1375 Active synthesis of type I collagen homotrimer in Dupuytren's fibrosis is unaffected by anti-TNF-α treatment
Williamson, K.; Lee, K. J.; Beamish, E. L.; Carter, A.; Gumbs, J. A.; Cooper, G.; Cheung, G.; Brown, D.; Pettitt, R.; Comerford, E. J.; Clegg, P. D.; Canty-Laird, E. G.
10.1101/2020.07.13.195107 — cell biology — Posted on 2023-08-24
1378 Neurodevelopmental defects in a mouse model of O-GlcNAc transferase intellectual disability
Authier, F.; Ondruskova, N.; Ferenbach, A. T.; McNeilly, A.; van Aalten, D. M. F.
10.1101/2023.08.23.554427 — neuroscience — Posted on 2023-08-24
1380 Temporal Contrast Enhancement in Thermosensation: A Framework for Understanding Paradoxical Heat Sensation
Mitchell, A. G.; Fischer Ehmsen, J.; Basinska, M.; Courtin, A. S.; Bohme, R. A.; Sardeto Deolindo, C.; Allen, M. G.; Sandberg, K.; Fardo, F.
10.1101/2023.08.23.554435 — neuroscience — Posted on 2023-08-24
1381 Altered metabolic function induced by amyloid-beta oligomers and PSEN1-mutations in iPSC-derived astrocytes.
Hill, E. J.; Elsworthy, R. J.; Finelli, M.; Alqattan, S.; Dunleavy, C.; King, M.; Ludlam, A.; Allen, S. L.; Prosser, S. P.; Chen, R.; Martinez Jarquin, S.; Kim, D.-H.; Brown, J. E.; Parri, H.; Aldred, S.
10.1101/2023.08.23.554346 — neuroscience — Posted on 2023-08-24
1382 Engineered Wnt7a ligands rescue blood brain barrier and neurobehavioral deficits in a mouse model of COVID-19
Trevino, T. N.; Fogel, A. B.; Class, J.; Sanborn, M. A.; Vanhollebeke, B.; Rehman, J.; Tai, L. M.; Richner, J. M.; Lutz, S. E.
10.1101/2022.06.02.494552 — neuroscience — Posted on 2023-08-24
1385 Cerebral perfusion alterations in temporal lobe epilepsy: Structural underpinnings and network disruptions
Ngo, A.; Royer, J.; Rodriguez-Cruces, R.; Xie, K.; DeKraker, J.; Auer, H.; Tavakol, S.; Lam, J.; Schrader, D.; Dudley, R. W. R.; Bernasconi, A.; Ladbon-Bernasconi, N.; Frauscher, B.; Lariviere, S.; Bernhardt, B. C.
10.1101/2023.08.22.553552 — neuroscience — Posted on 2023-08-24
1386 Morphology and ultrastructure of external sense organsof Drosophila larvae
Richter, V.; Rist, A.; Kislinger, G.; Laumann, M.; Schoofs, A.; Miroschnikow, A.; Pankratz, M.; Cardona, A.; Thum, A. S.
10.1101/2023.08.23.554405 — neuroscience — Posted on 2023-08-24
1390 Urolithin A induces cardioprotection and enhanced mitochondrial quality during natural aging and heart failure
Liu, S.; Faitg, J.; Tissot, C.; Konstantopoulos, D.; Laws, R.; Bourdier, G.; Andreux, P. A.; Davey, T.; Singh, A.; Rinsch, C.; Marcinek, D. J.; D'Amico, D.
10.1101/2023.08.22.554375 — cell biology — Posted on 2023-08-24
1392 Mild uncoupling of mitochondria synergistically enhances senolytic specificity and sensitivity of BH3 mimetics
Fielder, E.; Ishaq, A.; Low, E.; Laws, J.; Calista, A.; Castle, J.; von Zglinicki, T.; Miwa, S.
10.1101/2023.08.23.554476 — cell biology — Posted on 2023-08-23
1393 Separating cognitive and motor processes in the behaving mouse
Hasnain, M. A.; Birnbaum, J. E.; Nunez, J. L. U.; Hartman, E.; Chandrasekaran, C.; Economo, M. N.
10.1101/2023.08.23.554474 — neuroscience — Posted on 2023-08-24
1394 Supporting materials: Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of Port Wine Birthmark
Nguyen, V.; Gao, C.; Hochman, M.; Kravitz, J.; Chen, E.; Friedman, H.; Wenceslau, C.; Chen, D.; Wang, Y.; Nelson, J. S.; Jegga, A. G.; Tan, W.
10.1101/2023.07.02.547408 — cell biology — Posted on 2023-08-24
1395 Circadian rhythm disruptions associated with opioid use disorder in the synaptic proteomes of the human dorsolateral prefrontal cortex and nucleus accumbens
Puig, S.; Xue, X.; Salisbury, R.; Shelton, M. A.; Kim, S.-M.; Hildebrand, M. A.; Glausier, J. R.; Freyberg, Z.; Tseng, G. C.; Yocum, A. K.; Lewis, D. A.; Seney, M. L.; MacDonald, M. L.; Logan, R. W.
10.1101/2023.04.07.536056 — neuroscience — Posted on 2023-08-24
1396 Microglial TNFα controls GABAAR plasticity, sleep slow waves and memory consolidation
Pinto, M. J.; Bizien, L.; Fabre, J. M.; Thukanovic, N.; Cottin, L.; Lepetz, V.; Henderson, F.; Pujol, M.; Sala, R. W.; Tarpin, T.; Popa, D.; Triller, A.; Lena, C.; Fabre, V.; Bessis, A.
10.1101/2022.02.21.481254 — neuroscience — Posted on 2023-08-24
1397 Dentate Neurogenesis Modulates Dorsal Hippocampal Excitation/Inhibition Balance Crucial for Cognitive Flexibility
Li, H.; Tamura, R.; Hayashi, D.; Asai, H.; Koga, J.; Ando, S.; Yokota, S.; Kaneko, J.; Sakurai, K.; Sumiyoshi, A.; Yamamoto, T.; Hikishima, K.; Tanaka, K. Z.; McHugh, T.; Hisatsune, T.
10.1101/2023.02.22.529526 — neuroscience — Posted on 2023-08-24
1400 Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses
Inglebert, Y.; Wu, P. Y.; Tourbina-Kolomiets, J.; Dang, C. L.; McKinney, R. A.
10.1101/2023.08.21.554176 — neuroscience — Posted on 2023-08-24
1402 FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Parekh, P.; Fan, C. C.; Frei, O.; Palmer, C. E.; Smith, D. M.; Makowski, C.; Iverson, J.; Pecheva, D.; Holland, D.; Loughnan, R.; Nedelec, P.; Thompson, W. K.; Hagler, D. J.; Andreassen, O. A.; Jernigan, T. L.; Nichols, T.; Dale, A. M.
10.1101/2021.10.27.466202 — neuroscience — Posted on 2023-08-24
1403 Zona incerta distributes a broad movement signal that modulates behavior
Hormigo, S.; Zhou, J.; Chabbert, D.; sajid, M.; Busel, N.; Castro-Alamancos, M. A.
10.1101/2023.06.21.545874 — neuroscience — Posted on 2023-08-24
1404 Homeostatic regulation of REM sleep by the preoptic area of the hypothalamus
Maurer, J. J.; Lin, A.; Jin, X.; Hong, J.; Sathi, N.; Cardis, R.; Osorio-Forero, A.; Lüthi, A.; Weber, F.; Chung, S.
10.1101/2023.08.22.554341 — neuroscience — Posted on 2023-08-23
1405 REVEALS: An Open Source Multi Camera GUI For Rodent Behavior Acquisition
Phadke, R. A.; Wetzel, A. M.; Fournier, L. A.; Sha, M.; Padro-Luna, N. M.; Cruz-Martin, A.
10.1101/2023.08.22.554365 — neuroscience — Posted on 2023-08-23
1408 HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in familial and sporadic amyotrophic lateral sclerosis models
Silvestri, B.; Mochi, M.; Mawrie, D.; de Turris, V.; Colantoni, A.; Borhy, B.; Garone, M. G.; Zammerilla, C. P.; Pandey, U. B.; Rosa, A.
10.1101/2023.08.22.554258 — neuroscience — Posted on 2023-08-23
1410 Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis
Drexhage, L. Z.; Zhang, S.; DuPont, M.; Ragaller, F.; Sjule, E.; Caballero, J. C.; Deimel, L. P.; Robertson, H.; Russell, R. A.; Dushek, O.; Sezgin, E.; Karaji, N.; Sattentau, Q. J.
10.1101/2023.08.22.554267 — cell biology — Posted on 2023-08-23
1415 Intersectin and Endophilin condensates prime synaptic vesicles for release site replenishment
Ogunmowo, T.; Hoffmann, C.; Pepper, R.; Wang, H.; Gowrisankaran, S.; Ho, A.; Raychaudhuri, S.; Cooper, B. H.; Milosevic, I.; Milovanovic, D.; Watanabe, S.
10.1101/2023.08.22.554276 — neuroscience — Posted on 2023-08-23
1417 Correlating stress reduction and eye movement patterns in a world famous Kyoto Japanese garden
Goto, S.; Takase, H.; Yamaguchi, K.; Tamoki, K.; Sun, M.; Koga, A.; Tiankai, L.; Poy, I.; Herrup, K.
10.1101/2023.08.21.554170 — neuroscience — Posted on 2023-08-23
1420 The three-dimensionally articulated oral apparatus of a Devonian heterostracan sheds light on feeding in Palaeozoic jawless fishes
Dearden, R. P.; Jones, A.; Giles, S.; Lanzetti, A.; Grohganz, M.; Johanson, Z.; Lautenschlager, S.; Randle, E.; Donoghue, P.; Sansom, I. J.
10.1101/2023.08.22.554283 — paleontology — Posted on 2023-08-23
1422 Role of a Pdlim5:PalmD complex in directing dendrite morphology
Srivastava, Y.; Donta, M.; Mireles, L. L.; Paulucci-Holthauzen, A.; Waxham, M. N.; McCrea, P. D.
10.1101/2023.08.22.553334 — neuroscience — Posted on 2023-08-23
1424 Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases
Endo, H.; Ono, M.; Takado, Y.; Matsuoka, K.; Takahashi, M.; Tagai, K.; Kataoka, Y.; Hirata, K.; Takahata, K.; Seki, C.; Kokubo, N.; Fujinaga, M.; Mori, W.; Nagai, Y.; Mimura, K.; Kumata, K.; Kikuchi, T.; Shimozawa, A.; Mishra, S. K.; Yamaguchi, Y.; Shimizu, H.; Kakita, A.; Takuwa, H.; Shinotoh, H.; Shimada, H.; Kimura, Y.; Ichise, M.; Suhara, T.; Minamimoto, T.; Sahara, N.; Kawamura, K.; Zhang, M.-R.; Hasegawa, M.; Higuchi, M.
10.1101/2020.10.23.349860 — neuroscience — Posted on 2023-08-23
1426 Mitochondrial protein FKBP8 captures PDZD8 to form mitochondria-ER contacts
Nakamura, K.; Aoyama-Ishiwatari, S.; Nagao, T.; Paaran, M.; Obara, C. J.; Sakurai-Saito, Y.; Johnston, J.; Du, Y.; Suga, S.; Tsuboi, M.; Nakakido, M.; Tsumoto, K.; Kishi, Y.; Gotoh, Y.; Kwak, C.; Rhee, H.-W.; Seo, J. K.; Kosako, H.; Potter, C.; Carragher, B.; Lippincott-Schwartz, J.; Polleux, F.; Hirabayashi, Y.
10.1101/2023.08.22.554218 — cell biology — Posted on 2023-08-22
1427 C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer's model
Schartz, N. D.; Liang, H. Y.; Carvalho, K.; Chu, S.-H.; Mendoza-Arvilla, A.; Petrisko, T. J.; Gomez-Arboledas, A.; Mortazavi, A.; Tenner, A.
10.1101/2023.08.22.554306 — neuroscience — Posted on 2023-08-22
1428 Neuroticism/negative emotionality is associated with increased reactivity to uncertain threat in the bed nucleus of the stria terminalis, not the amygdala
Grogans, S. E.; Hur, J.; Barstead, M. G.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Fox, A. S.; Smith, J. F.; DeYoung, K. A.; Shackman, A. J.
10.1101/2023.02.09.527767 — neuroscience — Posted on 2023-08-22
1429 CuticleTrace: A toolkit for capturing cell outlines of leaf cuticle with implications for paleoecology and paleoclimatology
Lloyd, B. A.; Barclay, R. S.; Dunn, R. E.; Currano, E. D.; Mohamaad, A. I.; Skersies, K.; Punyasena, S. W.
10.1101/2023.07.23.550217 — paleontology — Posted on 2023-08-22
1430 Neural correlates of individual odor preference in Drosophila
Churgin, M.; Lavrentovich, D.; Smith, M. A.-Y.; Gao, R.; Boyden, E. S.; de Bivort, B. L.
10.1101/2021.12.24.474127 — neuroscience — Posted on 2023-08-22
1432 Profound seizure suppression and disease modification by targeting JAK1, a key driver of a pro-epileptogenic gene network.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A. S.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-08-22
1437 DNL343 is an investigational CNS penetrant eIF2B activator that prevents and reverses the effects of neurodegeneration caused by the Integrated Stress Response
Yulyaningsih, E.; Suh, J. H.; Fanok, M. H.; Chau, R.; Solanoy, H.; Takahashi, R.; Bakardjiev, A. I.; Becerra, I.; Benitez, N. B.; Chiu, C.-L.; Davis, S. S.; Dowdle, W. E.; Earr, T.; Estrada, A. E.; Gill, A.; Ha, C.; Haddick, P. C. G.; Henne, K. R.; Larhammar, M.; Leung, A. W.; Maciuca, R.; Memarzadeh, B.; Nguyen, H. N.; Nugent, A.; Osipov, M.; Ran, Y.; Rebadulla, K.; Roche, E.; Sandmann, T.; Wang, J.; Lewcock, J. W.; Scearce-Levie, K.; Kane, L. A.; Sanchez, P. E.
10.1101/2023.08.21.554203 — neuroscience — Posted on 2023-08-22
1442 A non-genetic model of vascular shunts informs on the cellular mechanisms of formation and resolution of arteriovenous malformations
Ouarne, M.; Pena, A.; Ramalho, D.; Conchinha, N.; Costa, T.; Figueiredo, A.; Saraiva, M.; Carvalho, Y.; Misikova, L.; Oh, P.; Franco, C.
10.1101/2023.08.21.554159 — cell biology — Posted on 2023-08-22
1444 Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution
Caporale, N.; Castaldi, D.; Rigoli, M. T.; Cheroni, C.; Trattaro, S.; Valenti, A.; Bonfanti, M.; Stucchi, S.; Tobon, A. L.; Ricca, D.; Lessi, M.; Pezzali, M.; Vitriolo, A.; Schmid, K.; Heinig, M.; Theis, F. J.; Villa, C. E.; Testa, G.
10.1101/2023.08.21.553507 — neuroscience — Posted on 2023-08-22
1446 Single nuclei transcriptomics of human and monkey striatum implicates DNA damage and neuroinflammation in opioid use disorder
Phan, B. N.; Ray, M. H.; Xue, X.; Fu, C.; Fenster, R. J.; Kohut, S. J.; Bergman, J.; Haber, S. N.; Mccullough, K. M.; Kuppe-Fish, M. K.; Glausier, J. R.; Su, Q.; Tipton, A. E.; Lewis, D. A.; Freyberg, Z.; Tseng, G. C.; Ressler, K. J.; Russek, S. J.; Alekseyev, Y.; Seney, M. L.; Pfenning, A. R.; Logan, R. W.
10.1101/2023.05.17.541145 — neuroscience — Posted on 2023-08-22
1451 WWP2 MEDIATES THE METABOLIC REPROGRAMMING OF RENAL MYOFIBROBLASTS TO PROMOTE KIDNEY FIBROSIS
Chen, H.; You, R.; Guo, J.; Zhou, W.; Chew, G.; Devapragash, N.; Loh, J. Z.; Gesualdo, L.; Li, Y.; Jiang, Y.; Tan, E. L. S.; Chen, S.; Pontrelli, P.; Pesce, F.; Behmoaras, J.; Zhang, A.; Petretto, E. G.
10.1101/2023.08.22.554242 — cell biology — Posted on 2023-08-22
1453 Mitochondrial protein FKBP8 captures PDZD8 to form mitochondria-ER contacts
Nakamura, K.; Aoyama-Ishiwatari, S.; Nagao, T.; Paaran, M.; Obara, C. J.; Sakurai-Saito, Y.; Johnston, J.; Du, Y.; Suga, S.; Tsuboi, M.; Nakakido, M.; Tsumoto, K.; Kishi, Y.; Gotoh, Y.; Kwak, C.; Rhee, H.-W.; Seo, J. K.; Kosako, H.; Potter, C.; Carragher, B.; Lippincott-Schwartz, J.; Polleux, F.; Hirabayashi, Y.
10.1101/2023.08.22.554218 — cell biology — Posted on 2023-08-22
1454 Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses
Inglebert, Y.; Wu, P. Y.; Tourbina-Kolomiets, J.; Dang, C. L.; McKinney, R. A.
10.1101/2023.08.21.554176 — neuroscience — Posted on 2023-08-22
1455 Relationship between reactive astrocytes, by SMBT-1 imaging, with amyloid-beta, tau, glucose metabolism, and microgliosis in mouse models of Alzheimer's disease
Kong, Y.; Maschio, C.; Shi, X.; Yao, B.; Xie, F.; Zuo, C.; Konietzko, U.; Shi, K.; Rominger, A.; Xiao, J.; Huang, Q.; Nitsch, R. M.; Guan, Y.; Ni, R.
10.1101/2023.08.21.554163 — neuroscience — Posted on 2023-08-22
1458 Ubiquitin-driven protein condensation promotes clathrin-mediated endocytosis
Yuan, F.; Gollapudi, S.; Day, K.; Ashby, G.; Sangani, A.; Malady, B.; Wang, L.; Lafer, E. M.; Huibregtse, J.; Stachowiak, J.
10.1101/2023.08.21.554139 — cell biology — Posted on 2023-08-22
1459 Cell therapy with IL-10-producing group 2 innate lymphoid cells suppresses Graft-versus-Host disease
Reid, K. T.; Colpitts, S. J.; Mathews, J. A.; Carreira, A. S.; Murphy, J. M.; Borovsky, D. T.; Cui, W.; Moya, T. A.; Sachewsky, N.; An, J.; Xia, Y.; Mortha, A.; Lee, J. B.; Zhang, L.; Novitzky-Basso, I.; Mattsson, J.; Crome, S. Q.
10.1101/2023.08.21.554158 — immunology — Posted on 2023-08-22
1460 Olfaction regulates peripheral mitophagy and mitochondrial function
Dishart, J. G.; Pender, C.; Shen, K.; Zhang, H.; Ly, M.; Webb, M.; Dillin, A. G.
10.1101/2023.08.21.554156 — neuroscience — Posted on 2023-08-22
1462 Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer
Bahnassy, S.; Stires, H.; Jin, L.; Tam, S.; Mobin, D.; Balachandran, M.; Podar, M. B.; McCoy, M. D.; Beckman, R. A.; Riggins, R. B.
10.1101/2023.08.21.554116 — cancer biology — Posted on 2023-08-22
1466 Joint representation learning for retrieval and annotation of genomic interval sets
Gharavi, E.; LeRoy, N. J.; Zheng, G.; Zhang, A.; Brown, D. E.; Sheffield, N. C.
10.1101/2023.08.21.554131 — bioinformatics — Posted on 2023-08-22
1468 Discovery of Novel Allosteric Sites of SARS-CoV-2 Papain-Like Protease (PLpro)
Ferreira, J. C.; Al Adem, K.; Fadl, S.; Villanueva, A. J.; Alzyoud, L.; Ghattas, M. A.; Rabeh, W. M.
10.1101/2023.05.16.540953 — biochemistry — Posted on 2023-08-22
1470 Active learning of enhancer and silencer regulatory grammar in photoreceptors
Friedman, R. Z.; Ramu, A.; Lichtarge, S.; Myers, C. A.; Granas, D. M.; Gause, M.; Corbo, J. C.; Cohen, B. A.; White, M. A.
10.1101/2023.08.21.554146 — genomics — Posted on 2023-08-22
1472 Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2
Littleton, S. H.; Trang, K. B.; Volpe, C. M.; Cook, K.; DeBruyne, N.; Maguire, J. A.; Weidekamp, M. A.; Boehm, K.; Chesi, A.; Pippin, J. A.; Anderson, S. A.; Wells, A. D.; Pahl, M. C.; Grant, S. F.
10.1101/2023.08.21.553157 — genetics — Posted on 2023-08-22
1474 Epiphytic and endophytic microbiome of the seagrass Zostera marina: Do they contribute to pathogen reduction in seawater?
Tasdemir, D.; Scarpato, S.; Utermann-Thuesing, C.; Jensen, T.; Bluemel, M.; Wenzel-Storjohann, A.; Welsch, C.; Echelmeyer, V. A.
10.1101/2023.08.21.554113 — ecology — Posted on 2023-08-22
1475 Maintaining intact parathyroid glands throughout life requires Dicer and microRNA-mediated mTORC1 signaling
Hassan, A.; Khalaily, N.; Kilav-Levin, R.; Del Castello, B.; Manley, N. R.; Ben-Dov, I. Z.; Naveh-Many, T.
10.1101/2023.08.21.554016 — developmental biology — Posted on 2023-08-22
1476 Morphodynamics of human early brain organoid development
Jain, A.; Gut, G.; Sanchis Calleja, F.; Okamoto, R.; Streib, S.; He, Z.; Zenk, F.; Santel, M.; Seimiya, M.; Holtackers, R.; Jansen, S. M. J.; Camp, J. G.; Treutlein, B.
10.1101/2023.08.21.553827 — developmental biology — Posted on 2023-08-22
1478 Mis-regulation of Zn and Mn homeostasis is a key phenotype of Cu stress in Streptococcus pyogenes.
Hong, Y.; Mackenzie, E. S.; Firth, S. J.; Bolton, J. F.; Stewart, L. J.; Waldron, K. J.; Djoko, K. Y.
10.1101/2022.09.28.509676 — microbiology — Posted on 2023-08-22
1479 Epigenetic mediated functional reprogramming of immune cells leads to HBsAg seroconversion in Hepatitis B Virus Reactivation patients
Sevak, J. K.; Islam, M.; Verma, G.; Saxena, A.; Babu E, P.; Parveen, S.; Jindal, A.; Sharma, M. K.; Ramakrishna, G.; Sarin, S. K.; Trehanpati, N.
10.1101/2023.08.21.554133 — immunology — Posted on 2023-08-22
1480 `Mind in Vitro' platforms: Versatile, scalable, robust and open solutions to interfacing with living neurons
Zhang, X.; Dou, Z.; Kim, S.-H.; Upadhyay, G.; Havert, D.; Kang, S.; Kazemi, K.; Huang, K.-Y.; Aydin, O.; Huang, R.; Rahman, S.; Ellis-Mohr, A.; Noblet, H. A.; Lim, K. H.; Chung, H. J.; Gritton, H. J.; Saif, M. T. A.; Kong, H. J.; Beggs, J. M.; Gazzola, M.
10.1101/2023.08.21.554033 — neuroscience — Posted on 2023-08-22
1484 Ocular TRPV1 deficiency protects from dry eye-induced corneal nerve damage
Pizzano, M.; Vereertbrugghen, A.; Cernutto, A.; Sabbione, F.; Keitelman, I. A.; Shiromizu, C. M.; Aguilar, D. V.; Fuentes, F.; Giordano, M. N.; Trevani, A. S.; Galletti, J. G.
10.1101/2023.08.21.554143 — neuroscience — Posted on 2023-08-22
1492 EZH2 specifically regulates ISL1 during embryonic urinary tract formation
Mingrado, E.; Kalanithy, J.; Dworschak, G.; Ishorst, N.; Yilmaz, O.; Lindenberg, T.; Hollstein, R.; Felger, T.; Angrand, P.-O.; Reutter, H.; Odermatt, B.
10.1101/2023.08.21.554100 — genetics — Posted on 2023-08-22
1493 Spatial patterns in the diet of Gyps vultures in India and their implications for conservation
Ghosh-Harihar, M.; Yadav, N.; Gurung, N.; C.S., D.; B., S.; C.K., V.; Prakash, V.; Green, R. E.; Ramakrishnan, U.
10.1101/2023.08.21.554114 — ecology — Posted on 2023-08-22
1494 Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI.
Kapustin, A. N.; Tsakali, S. S.; Whitehead, M.; Chennell, G.; Wu, M.-Y.; Molenaar, C.; Kutikhin, A.; Bogdanov, L.; Sinitsky, M.; Rubina, K.; Clayton, A.; Verweij, F. J.; Pegtel, D. M.; Zingaro, S.; Lobov, A.; Zainullina, B.; Owen, D.; Parsons, M.; Cheney, R. E.; Warren, D.; Humphries, M. J.; Iskratsch, T.; Holt, M.; Shanahan, C. M.
10.1101/2023.08.17.551257 — cell biology — Posted on 2023-08-22
1495 CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β
Prise, I. E.; Jayaraman, V.; Kästele, V.; Daw, R. H.; Wemyss, K.; Bridgeman, H.; Tamburrano, S.; Strangward, P.; Chew, C.; Martens, L.; Scott, C. L.; Guilliams, M.; Adamson, A. D.; Konkel, J. E.; Shaw, T. N.; Grainger, J. R.
10.1101/2023.08.21.553672 — immunology — Posted on 2023-08-22
1496 Regional Differences in Progenitor Consumption Dynamics Shape Brain Growth during Development
Baumann, N.; Wagener, R.; Javed, A.; Abe, P.; Lopes, A.; Lavalley, A.; Fuciec, D.; Magrinelli, E.; Fievre, S.; Jabaudon, D.
10.1101/2023.08.21.553891 — neuroscience — Posted on 2023-08-22
1498 PI3Kα activity in PHGDH-low pancreatic epithelial cells limits tissue proliferative regeneration in cancer promoting conditions
Cayron, C.; Bozoglou, D.; Villard, A. V.; Reyes-Castellanos, G.; Therville, N.; Baer, R.; Arcucci, S.; Naud, N.; Tosolini, M.; Pont, F.; Ferreira Da Mota, D.; Gueraud, F.; Basset, C.; Carrier, A.; Pierre, F.; Thibault, B.; Dufresne, M.; Guillermet-Guibert, J.
10.1101/2023.08.22.554245 — pathology — Posted on 2023-08-22
1502 Screening for novel RyR2 inhibitors by ER Ca2+ monitoring
Takenaka, M.; Kodama, M.; Murayama, T.; Ishigami-Yuasa, M.; Mori, S.; Ishida, R.; Suzuki, J.; Kanemaru, K.; Sugihara, M.; Iino, M.; Miura, A.; Nishio, H.; Morimoto, S.; Kagechika, H.; Sakurai, T.; Kurebayashi, N.
10.1101/2023.08.21.553510 — pharmacology and toxicology — Posted on 2023-08-22
1504 Thermoplasmonic modulation of cardiomyocytes activity with local temperature read-out
Guo, F.; Yu, W.; Deschaume, O.; Jooken, S.; Liu, L.; Wei, Q.; Thielemans, W.; Bartic, C.
10.1101/2023.08.21.554091 — bioengineering — Posted on 2023-08-22
1506 Sphingosine 1-phosphate receptor 1 inhibition induces a pro-apoptotic signaling cascade in T cells
Dixit, D.; Hallisey, V. M.; Zhu, E. Y. S.; Okuniewska, M.; Cadwell, K.; Chipuk, J. E.; Axelrad, J.; Schwab, S. R.
10.1101/2023.08.21.554104 — immunology — Posted on 2023-08-22
1510 Brain asymmetries from midlife to old adulthood and hemispheric brain age
Korbmacher, M.; van der Meer, D.; Beck, D.; de Lange, A.-M. G.; Eikefjord, E.; Lundervold, A.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2023.08.21.554103 — neuroscience — Posted on 2023-08-22
1511 Just a phase? Causal probing reveals spurious phasic dependence of sensory perception
Vinao-Carl, M. L.; Gal-Shohet, Y. R.; Rhodes, E.; Li, J.; Hampshire, A.; Sharp, D. J.; Grossman, N.
10.1101/2023.08.21.554096 — neuroscience — Posted on 2023-08-22
1512 Gaming expertise induces meso-scale brain plasticity and efficiency mechanisms as revealed by whole-brain modeling
Coronel-Oliveros, C.; Medel, V.; Orellana, S.; Rodino, J.; Lehue, F.; Cruzat, J.; Tagliazucchi, E.; Brzezicka, A.; Orio, P.; Kowalczyk-Grebska, N.; Ibanez, A.
10.1101/2023.08.21.554072 — neuroscience — Posted on 2023-08-22
1513 Improving fine-mapping by modeling infinitesimal effects
Cui, R.; Elzur, R. A.; Kanai, M.; Ulirsch, J. C.; Weissbrod, O.; Daly, M.; Neale, B.; Fan, Z.; Finucane, H. K.
10.1101/2022.10.21.513123 — bioinformatics — Posted on 2023-08-22
1519 Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
Liu, C. S. C.; Mandal, T.; Biswas, P.; Hoque, M. A.; Bandopadhyay, P.; Sinha, B. P.; Sarif, J.; D'Rozario, R.; Sinha, D. K.; Sinha, B.; Ganguly, D.
10.1101/2022.08.16.504114 — immunology — Posted on 2023-08-22
1523 Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane
Morel, C.; Lemerle, E.; Tsai, F.-C.; Obadia, T.; Srivastava, N.; Marechal, M.; Salles, A.; Albert, M.; Stefani, C.; Benito, Y.; Vandenesch, F.; Lamaze, C.; Vassilopoulos, S.; Piel, M.; Bassereau, P.; Gonzalez-Rodriguez, D.; Leduc, C.; Lemichez, E.
10.1101/2022.09.27.509635 — biophysics — Posted on 2023-08-22
1525 Phosphorylation-controlled cohesion of a nuclear condensate regulates mRNA retention
McIntyre, A. B. R.; Tschan, A.; Meyer, K.; Walser, S.; Rai, A. K.; Fujita, K.; Pelkmans, L.
10.1101/2023.08.21.554101 — cell biology — Posted on 2023-08-22
1527 Non-antibiotic pharmaceuticals exhibit toxicity against Escherichia coli at environmentallyrelevant concentrations with no evolution of cross-resistance to antibiotics
Hall, R. J.; Snaith, A. E.; Element, S.; Moran, R. A.; Smith, H.; Cummins, E. A.; Bottery, M. J.; Chowdhury, K. F.; Sareen, D.; Ahmad, I.; Blair, J. M. A.; Carter, L. J.; McNally, A.
10.1101/2023.08.21.554069 — microbiology — Posted on 2023-08-22
1528 The pathogenesis of experimental Emergomycosis in mice.
Hoft, M. A.; Duvenage, L.; Salie, S.; Keeton, R.; Botha, A.; Schwartz, I. S.; Govender, N. P.; Brown, G. D.; Hoving, J. C.
10.1101/2023.08.21.554076 — immunology — Posted on 2023-08-22
1529 A simplified mesoscale 3D model for characterizing fibrinolysis under flow conditions
Petkantchin, R.; Rousseau, A.; Eker, O.; Boudjeltia, K. Z.; Raynaud, F.; Chopard, B.
10.1101/2023.05.09.539942 — biophysics — Posted on 2023-08-22
1530 Emergent Simplicities in Stochastic Intergenerational Homeostasis
Joshi, K.; Wright, C. S.; Ziegler, K. F.; Spiers, E. M.; Crosser, J. T.; Eschker, S.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.01.18.524627 — biophysics — Posted on 2023-08-22
1531 LRTK: A platform agnostic toolkit for linked-read analysis of both human genomes and metagenomes
Yang, C.; Zhang, Z.; Huang, Y.; Liao, X.; Liao, H.; Xiao, J.; Veldsman, W. P.; Yin, K.; Fang, X.; Zhang, L.
10.1101/2022.08.10.503458 — bioinformatics — Posted on 2023-08-22
1532 A dynamic in vitro model of Down Syndrome neurogenesis with Trisomy 21 gene dosage correction
Bansal, P.; Banda, E. C.; Glatt-Deeley, H. R.; Stoddard, C.; Linsley, J. W.; Arora, N.; Ahern, D. T.; Kondaveeti, Y.; Nicouleau, M.; Sabariego-Navarro, M.; Dierssen, M.; Finkbeiner, S.; Pinter, S. F.
10.1101/2022.05.11.491519 — developmental biology — Posted on 2023-08-22
1533 Discovery of embryonically derived bipotent endothelial-macrophage progenitor cells in postnatal aorta
Williamson, A. E.; Liyanage, S.; Hassanshahi, M.; Dona, M. S. I.; Toledo-Flores, D.; Tran, D. X. A.; Dimasi, C.; Schwarz, N.; Fernando, S.; Salagaras, T.; Long, A.; Kazenwadel, J.; Harvey, N. L.; Drummond, G. R.; Vinh, A.; Chandrakanthan, V.; Misra, A.; Neufeld, Z.; Tan, J. T. M.; Martelotto, L. G.; Polo, J. M.; Bonder, C. S.; Pinto, A. R.; Sharma, S.; Nicholls, S. J.; Bursill, C. A.; Psaltis, P. J.
10.1101/2021.10.18.464001 — cell biology — Posted on 2023-08-22
1534 Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases
Dhawka, L.; Palfini, V.; Hambright, E.; Blanco, I.; Poon, C.; Kahl, A.; Resch, U.; Bhawal, R.; Benakis, C.; Balachandran, V.; Zhang, S.; Iadecola, C.; Hochrainer, K.
10.1101/2023.08.21.552860 — neuroscience — Posted on 2023-08-21
1535 Spatial summation of pain is associated with pain expectations: Results from home-based paradigm
Nastaj, J.; Skalski, J.; Budzisz, A.; Szikszay, T. M.; Swoboda, S.; Kowalska, W.; Nowak, D.; Zbroja, E.; Kruszyna, N.; Jakubinska, M.; Grygny, D.; Polczyk, R.; Malecki, A.; Luedtke, K.; Adamczyk, W. M.
10.1101/2022.09.30.510274 — physiology — Posted on 2023-08-21
1538 Inferring compound heterozygosity from large-scale exome sequencing data
Guo, M. H.; Francioli, L. C.; Stenton, S. L.; Goodrich, J. K.; Watts, N. A.; Singer-Berk, M.; Groopman, E.; Darnowsky, P. W.; Solomonson, M.; Baxter, S.; gnomAD Project Consortium, ; Tiao, G.; Neale, B. M.; Hirschhorn, J. N.; Rehm, H. L.; Daly, M. J.; O'Donnell-Luria, A.; Karczewski, K. J.; MacArthur, D. G.; Samocha, K. E.
10.1101/2023.03.19.533370 — genomics — Posted on 2023-08-21
1539 Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells
Liu, S.; Yu, Y.; Ren, B.-G.; Yehezkel, T.; Obert, C.; Smith, M.; Wang, W.; Ostrowska, A.; Soto-Gutierrez, A.; Luo, J.
10.1101/2023.03.16.532991 — genomics — Posted on 2023-08-21
1540 Egg size variation in the context of polyandry: a case study using long-term field data from snowy plovers
Eberhart-Hertel, L. J.; Falcao Rodrigues, L.; Krietsch, J.; Eberhart-Hertel, A. G.; Cruz-Lopez, M.; Vazquez-Rojas, K. A.; Gonzalez-Medina, E.; Schroeder, J.; Küpper, C.
10.1101/2020.08.07.240150 — evolutionary biology — Posted on 2023-08-21
1542 Dynamics of chromatin accessibility during human first-trimester neurodevelopment
Mannens, C. C. A.; Hu, L.; Lonnerberg, P.; Schipper, M.; Reagor, C.; Li, X.; He, X.; Barker, R. A.; Sundstrom, E.; Posthuma, D.; Linnarsson, S.
10.1101/2023.08.18.553878 — developmental biology — Posted on 2023-08-21
1545 Transcriptomic Evaluation of Stress Vulnerability Network using Single Cell RNA-Seq in mouse Prefrontal Cortex
Hing, B.; Mitchell, S. B.; Eberle, M.; Filali, Y.; Hultman, I.; Matkovich, M.; Kasturirangan, M.; Wyche, W.; Jimenez, A.; Velamuri, R.; Johnson, M.; Srivastava, S.; Hultman, R.
10.1101/2023.05.14.540705 — neuroscience — Posted on 2023-08-21
1546 Chitosan stimulates root hair callose deposition and inhibits root hair growth
Drs, M.; Haluska, S.; Skrabalkova, E.; Krupar, P.; Potocka, A.; Brejskova, L.; Muller, K.; Serrano, N.; Voxeur, A.; Vernhettes, S.; Ortmannova, J.; Caldarescu, G.; Fendrych, M.; Potocky, M.; Zarsky, V.; Pecenkova, T.
10.1101/2023.07.30.551171 — plant biology — Posted on 2023-08-21
1547 Multiplex imaging of localized prostate tumors reveals changes in mast cell type composition and spatial organization of AR-positive cells in the tumor microenvironment
Ak, C.; Sayar, Z.; Thibault, G.; Burlingame, E.; Eng, J.; Chitsazan, A.; Adey, A.; Boniface, C.; Spellman, P. T.; Thomas, G. V.; Kopp, R.; Demir, E.; Chang, Y. H.; Stavrinides, V.; Eksi, S. E.
10.1101/2023.08.18.553854 — cancer biology — Posted on 2023-08-21
1550 Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease
Huang, Y.; Wang, J.; Chin, D.; Mancino, V.; Pham, J.; Li, H.; Jiang, K.; Ram, A.; Poon, C.; Ho, P.-Y.; Peti-Peterdi, J.; Gyarmati, G.; Hallows, K. R.; Chung, E. J.
10.1101/2022.10.18.512444 — bioengineering — Posted on 2023-08-21
1553 Understanding inter-individual social networks in mixed-species bird flocks
Bharadwaj, A.; Thapa, A.; Bhat, A.; Biswakarma, A.; Tamang, B.; Munda, B.; Biswakarma, B.; Pradhan, D. K.; Tamang, D.; Pradhan, K.; K Rai, M.; Chamling Rai, P.; Rai, R.; Rai, S.; Srinivasan, U.
10.1101/2023.04.13.536662 — ecology — Posted on 2023-08-21
1555 Deep screening of proximal and distal splicing-regulatory elements in a native sequence context
Recinos, Y.; Ustianenko, D.; Yeh, Y.-T.; Wang, X.; Jacko, M.; Yesantharao, L. V.; Wu, Q.; Zhang, C.
10.1101/2023.08.21.554109 — molecular biology — Posted on 2023-08-21
1556 Discovery of a first-in-class small molecule ligand for WDR91 using DNA-encoded chemical library selection followed by machine learning
Ahmad, S.; Xu, J.; Feng, J. A.; Hutchinson, A.; Zeng, H.; Ghiabi, P.; Dong, A.; Centrella, P. A.; Clark, M. A.; Guie, M.-A.; Guilinger, J. P.; Keefe, A. D.; Zhang, Y.; Cerruti, T.; Cuozzo, J. W.; Rechenberg, M. v.; Bolotokova, A.; Li, Y.; Loppnau, P.; Seitova, A.; Li, Y.-Y.; Santhakumar, V.; Brown, P.; Ackloo, S.; Halabelian, L.
10.1101/2023.08.21.552681 — molecular biology — Posted on 2023-08-21
1559 Human Saliva Modifies Growth, Biofilm Architecture and Competitive Behaviors of Oral Streptococci
Choi, A.; Dong, K.; Williams, E.; Pia, L.; Batagower, J.; Bending, P.; Shin, I.; Peters, D. I.; Kaspar, J. R.
10.1101/2023.08.21.554151 — microbiology — Posted on 2023-08-21
1561 Non-antibiotic pharmaceuticals exhibit toxicity against Escherichia coli at environmentallyrelevant concentrations with no evolution of cross-resistance to antibiotics
Hall, R. J.; Snaith, A. E.; Element, S.; Moran, R. A.; Cummins, E. A.; Bottery, M. J.; Chowdhury, K. F.; Sareen, D.; Ahmad, I.; Blair, J. M. A.; Carter, L. J.; McNally, A.
10.1101/2023.08.21.554069 — microbiology — Posted on 2023-08-21
1568 ATUM-Tomo: A multi-scale approach to cellular ultrastructure by combined volume scanning electron microscopy and electron tomography
Kislinger, G.; Fabig, G.; Wehn, A. C.; Rodriguez, L.; Jiang, H.; Niemann, C.; Klymchenko, A. S.; Plesnila, N.; Misgeld, T.; Mueller-Reichert, T.; Khalin, I.; Schifferer, M.
10.1101/2023.07.12.547497 — neuroscience — Posted on 2023-08-21
1569 Brain-wide oscillatory network encodes an aggressive internal state
Grossman, Y. S.; Talbot, A.; Gallagher, N. M.; Thomas, G.; Fink, A. J.; Walder-Christensen, K. K.; Russo, S.; Carlson, D. E.; Dzirasa, K.
10.1101/2022.12.07.519272 — neuroscience — Posted on 2023-08-21
1570 Generalizable links between symptoms of borderline personality disorder and functional connectivity
Shafiei, G.; Keller, A. S.; Bertolero, M.; Shanmugan, S.; Bassett, D. S.; Chen, A. A.; Covitz, S.; Houghton, A.; Luo, A.; Mehta, K.; Salo, T.; Shinohara, R. T.; Fair, D.; Hallquist, M. N.; Satterthwaite, T. D.
10.1101/2023.08.03.551534 — neuroscience — Posted on 2023-08-21
1575 Regulatory variation controlling architectural pleiotropy in maize
Bertolini, E.; Rice, B. R.; Braud, M.; Yang, J.; Hake, S.; Strable, J.; Lipka, A. E.; Eveland, A. L.
10.1101/2023.08.19.553731 — plant biology — Posted on 2023-08-21
1577 Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections
Schupp, P. G.; Shelton, S. J.; Brody, D. J.; Eliscu, R.; Johnson, B. E.; Mazor, T.; Kelley, K. W.; Potts, M. B.; McDermott, M. W.; Huang, E. J.; Lim, D. A.; Pieper, R. O.; Berger, M. S.; Costello, J. F.; Phillips, J. J.; Oldham, M. C.
10.1101/2023.06.21.545365 — cancer biology — Posted on 2023-08-21
1579 Flexiplex: A versatile demultiplexer and search tool for omics data
Davidson, N. M.; Amin, N.; Min Hao, L.; Wang, C.; Cheng, O.; Goeke, J. M.; Ritchie, M. E.; Wu, S.
10.1101/2023.08.21.554084 — bioinformatics — Posted on 2023-08-21
1582 Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery
Russell, C. N.; Carter, J. L.; Borgia, J. M.; Bush, J.; Calderon, F.; Gabarro, R.; Conway, S. J.; Mottram, J. C.; Wilkinson, A. J.; Jones, N. G.
10.1101/2023.08.21.554125 — biochemistry — Posted on 2023-08-21
1583 An Integrated Platform for in vivo Electrophysiology in Spatial Cognition Experiments
Brea Guerrero, A.; Oijala, M.; Moseley, S. C.; Tang, T.; Fletcher, F.; Zheng, Y.; Sanchez, L. M.; Clark, B.; Mcnaughton, B.; Wilber, A. A.
10.1101/2023.08.02.551691 — animal behavior and cognition — Posted on 2023-08-21
1586 Predictive microbial community changes across a temperature gradient
Sun, X.; Folmar, J.; Favier, A.; Pyenson, N.; Sanchez, A.; Rebolleda-Gomez, M.
10.1101/2023.07.28.550899 — ecology — Posted on 2023-08-21
1587 Yeast TLDc domain-containing proteins control assembly and subcellular localization of the V-ATPase
Klossel, S.; Zhu, Y.; Amado, L.; Bisinski, D. D.; Ruta, J.; Liu, F.; Gonzalez Montoro, A.
10.1101/2023.08.21.554079 — cell biology — Posted on 2023-08-21
1588 UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope
LIAO, Y.; Andronov, L.; Liu, X.; Lin, J.; Guerber, L.; Lu, L.; Agote-Aran, A.; Pangou, E.; Ran, L.; Kleiss, C.; Qu, M.; Schmucker, S.; Cirillo, L.; ZHANG, Z.; Riveline, D.; Gotta, M.; Klaholz, B.; Sumara, I.
10.1101/2023.08.21.554160 — cell biology — Posted on 2023-08-21
1589 Mutual homeostasis of charged proteins
Faraway, R.; Heaven, N. C.; Digby, H.; Wilkins, O. G.; Chakrabarti, A. M.; Iosub, I. A.; Knez, L.; Ameres, S. L.; Plaschka, C.; Ule, J.
10.1101/2023.08.21.554177 — molecular biology — Posted on 2023-08-21
1590 Functional characterization of ATP13A2 variants associated with distinct neurodegenerative disorders
Vrijsen, S.; El Asrar, R. A.; Houdou, M. C.; Van den Haute, C.; Baekelandt, V.; Lyons, J. A.; Eggermont, J.; Vangheluwe, P.
10.1101/2023.08.21.552829 — molecular biology — Posted on 2023-08-21
1592 Improved taxonomic annotation of Archaea communities using LotuS2, the Genome Taxonomy Database and RNAseq data
Grant, A.; Aleidan, A.; Davies, C. S.; Udochi, S. C.; Fritscher, J.; Bahram, M.; Hildebrand, F.
10.1101/2023.08.21.554127 — microbiology — Posted on 2023-08-21
1595 A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence
Hennart, M.; Crestani, C.; Bridel, S.; Armatys, N.; Bremont, S.; Carmi-Leroy, A.; Landier, A.; Passet, V.; Fonteneau, L.; Vaux, S.; Toubiana, J.; Badell-Ocando, E.; Brisse, S.
10.1101/2023.02.20.529124 — microbiology — Posted on 2023-08-21
1597 Mother-Infant Gut Viruses and their Bacterial Hosts: Transmission Patterns and Dynamics during Pregnancy and Early Life
Garmaeva, S.; Sinha, T.; Gulyaeva, A.; Kuzub, N.; Spreckels, J. E.; Andreu-Sanchez, S.; Gacesa, R.; Vich Vila, A.; Brushett, S.; Kruk, M.; Dekens, J.; Sikkema, J.; Kuipers, F.; Shkoporov, A.; Hill, C.; Scherjon, S.; Wijmenga, C.; Fu, J.; Kurilshikov, A.; Zhernakova, A.
10.1101/2023.08.21.554108 — microbiology — Posted on 2023-08-21
1599 Multi-omics analyses reveal rumen microbes and secondary metabolites that are unique to livestock species
Omondi, V. V.; Bosire, G. O.; Onyari, J. M.; Kibet, C.; Mwasya, S.; Onyonyi, V. N.; Getahun, M. N.
10.1101/2023.08.21.554168 — microbiology — Posted on 2023-08-21
1601 A patient-derived blood-brain barrier model for screening copper bis(thiosemicarbazone) complexes as potential therapeutics in Alzheimer's disease
Wasielewska, J. M.; Szostak, K.; McInnes, L. E.; Quek, H.; Chaves, J. C. S.; Liddell, J. R.; Koistinaho, J.; Oikari, L. E.; Donnelly, P. S.; White, A. R.
10.1101/2023.08.20.554047 — neuroscience — Posted on 2023-08-21
1603 LIANA+: an all-in-one cell-cell communication framework
Dimitrov, D.; Schäfer, P. S. L.; Farr, E.; Rodriguez Mier, P.; Lobentanzer, S.; Dugourd, A.; Tanevski, J.; Ramirez Flores, R. O.; Saez-Rodriguez, J.
10.1101/2023.08.19.553863 — systems biology — Posted on 2023-08-21
1604 Structural basis for the ligand recognition and signaling of free fatty acid receptors
Zhang, X.; Guseinov, A. A.; Jenkins, L.; Li, K.; Tikhonova, I.; Milligan, G.; Zhang, C.
10.1101/2023.08.20.553924 — pharmacology and toxicology — Posted on 2023-08-21
1610 Identification and functional characterisation of a locus for target site integration in Fusarium graminearum
Darino, M.; Urban, M.; Kaur, N.; Machado-Wood, A.; Grimwade-Mann, M.; Smith, D.; Beacham, A.; Hammond-kosack, K.
10.1101/2023.08.20.553861 — genetics — Posted on 2023-08-21
1611 Plasticity drives geographic variation and trait coordination in blue oak drought physiology
Anderegg, L. D. L.; Skelton, R. P.; Diaz, J.; Papper, P.; Ackerly, D. D.; Dawson, T. D. L.
10.1101/2023.08.20.553748 — ecology — Posted on 2023-08-21
1614 Connection between drug-mediated neurotransmission and salivary microbiome
Hisamatsu, D.; Ogata, Y.; Takeshige-Amano, H.; Suda, W.; Hatano, T.; Asaoka, D.; Mabuchi, Y.; Naraoka, Y.; Sato, N.; Asada, T.; Hattori, N.; Hattori, M.; Akazawa, C.
10.1101/2023.08.20.553896 — microbiology — Posted on 2023-08-21
1619 Structural and connectivity parameters reveal compensation patterns in young patients with non-progressive and slow-progressive cerebellar ataxia
Marchese, S. M.; Palesi, F.; Nigri, A.; Bruzzone, M. G.; Pantaleoni, C.; Wheeler-Kingshott, C. A. M. G.; D'Arrigo, S.; D'Angelo, E.; Cavallari, P.
10.1101/2023.08.20.554032 — neuroscience — Posted on 2023-08-21
1622 High-throughput Extracellular Matrix Proteomics of Human Lungs Enabled by Photocleavable Surfactant and diaPASEF
Bayne, E. F.; Buck, K. M.; Towler, A. G.; Zhu, Y.; Pergande, M. R.; Zhou, T.; Price, S. J.; Rossler, K. J.; Morales-Tirado, V.; Lloyd, S.; Wang, F.; He, Y.; Tian, Y.; Ge, Y.
10.1101/2023.08.17.553758 — systems biology — Posted on 2023-08-21
1624 Development and Validation of the Mentoring in Undergraduate Research Survey
Limeri, L. B.; Carter, N. T.; Hess, R. A.; Tuma, T. T.; Koscik, I.; Morrison, A. J.; Outlaw, B.; Royston, K. S.; Bridges, B. H. T.; Dolan, E. L.
10.1101/2023.08.19.553952 — scientific communication and education — Posted on 2023-08-21
1626 H3-OPT: Accurate prediction of CDR-H3 loop structures of antibodies with deep learning
Tian, B.; Chen, H.; Fan, X.; Zhu, S.; Pei, Y.; Zhang, X.; Zhang, X.; Liu, L.; Qian, F.
10.1101/2023.08.19.553933 — bioinformatics — Posted on 2023-08-21
1627 Injectable butyrate-prodrug micelles induce long-acting immune modulation and suppress autoimmune arthritis in mice
Cao, S.; Budina, E.; Wang, R.; Sabados, M.; Solanki, A.; Nguyen, M.; Hultgren, K.; Dhar, A.; Hubbell, J.
10.1101/2023.08.20.554028 — bioengineering — Posted on 2023-08-21
1628 Cross-tissue comparison of telomere length and quality metrics of DNA among individuals aged 8 to 70 years
Wolf, S. E.; Hastings, W. J.; Ye, Q.; Etzel, L.; Apsley, A. T.; Chiaro, C.; Heim, C. C.; Heller, T.; Noll, J. G.; Schreier, H. M. C.; Shenk, C. E.; Shalev, I.
10.1101/2023.08.19.553973 — genomics — Posted on 2023-08-21
1632 Harmonic decomposition of spacetime (HADES) framework characterises the spacetime hierarchy of the DMT brain state
Vohryzek, J.; Cabral, J.; Timmermann, C.; Atasoy, S.; Roseman, L.; Nutt, D.; Carhart-Harris, R.; Deco, G.; Kringelbach, M. L.
10.1101/2023.08.20.554019 — neuroscience — Posted on 2023-08-21
1633 Blunted glucocorticoid responsiveness to stress causes behavioral and biological alterations that lead to posttraumatic stress disorder vulnerability
Monari, S.; Guillot de Suduiraut, I.; Grosse, J.; Zanoletti, O.; Walker, S. E.; Mesquita, M.; Wood, T.; Cash, D.; Astori, S.; Sandi, C.
10.1101/2023.08.20.554001 — neuroscience — Posted on 2023-08-21
1636 Regulatory variation controlling architectural pleiotropy in maize
Bertolini, E.; Rice, B. R.; Braud, M.; Yang, J.; Hake, S.; Strable, J.; Lipka, A. E.; Eveland, A. L.
10.1101/2023.08.19.553731 — plant biology — Posted on 2023-08-21
1639 14K Prolactin Derived 14-Mer Antiangiogenic Peptide Targets Bradykinin-/Nitric Oxide-cGMP-Dependent Angiogenesis
Lee, J.; Kumar, P.; Natarajan, S.; Park, S. H.; Majumder, S.; Sundaresan, L.; Muralidhar, K.; Choi, J.-S.; Lee, H. J.; Chatterjee, S.
10.1101/2023.08.21.554080 — cancer biology — Posted on 2023-08-21
1641 Cell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone
Norton, E. S.; Whaley, L. A.; Jones, V. K.; Brooks, M. M.; Russo, M. N.; Morderer, D.; Jessen, E.; Schiapparelli, P.; Ramos-Fresnedo, A.; Zarco, N.; Carrano, A.; Rossoll, W.; Asmann, Y. W.; Lam, T. T.; Chaichana, K. L.; Anastasiadis, P. Z.; Quinones-Hinojosa, A.; Guerrero-Cazares, H.
10.1101/2023.08.19.553966 — cancer biology — Posted on 2023-08-21
1644 Consensus prediction of cell type labels with popV
Ergen, C.; Xing, G.; Xu, C.; Jayasuriya, M.; McGeever, E.; Pisco, A. O.; Streets, A. M.; Yosef, N.
10.1101/2023.08.18.553912 — bioinformatics — Posted on 2023-08-21
1645 mosaicMPI: a framework for modular data integration across cohorts and -omics modalities
Verhey, T. B.; Seo, H.; Gillmor, A.; Thoppey Manoharan, V.; Schriemer, D. C.; Morrissy, S.
10.1101/2023.08.18.553919 — bioinformatics — Posted on 2023-08-21
1646 Spatially resolved molecular analysis of host response to medical device implantation using the 3D OrbiSIMS
Suvannapruk, W.; Fisher, L. E.; Luckett, J. C.; Edney, M. K.; Kotowska, A. M.; Kim, D.-H.; Scurr, D. J.; Ghaemmaghami, A.; Alexander, M. R.
10.1101/2023.08.18.553860 — bioengineering — Posted on 2023-08-21
1647 No evidence for enhanced disease with polyclonal SARS-CoV-2 antibody in the ferret model.
Reed, D. S.; McElroy, A.; Barbeau, D.; McMillen, C.; Tilston-Lunel, N.; Nambulli, S.; Cottle, E.; Gilliland, T.; Rannulu, H.; Lundy, J.; Olsen, E.; O'Malley, K.; Xia, M.; Hartman, A.; Luke, T.; Egland, K.; Bausch, C.; Wu, H.; Sullivan, E.; Klimstra, W.; Duprex, P.
10.1101/2023.08.19.553970 — microbiology — Posted on 2023-08-21
1648 The pathogenesis of experimental Emergomycosis in mice.
Hoving, J. C.; Hoft, M. A.; Duvenage, L.; Salie, S.; Keeton, R.; Botha, A.; Schwartz, I. S.; Govender, N. P.; Brown, G. D.
10.1101/2023.08.21.554076 — immunology — Posted on 2023-08-21
1650 Prenatal environment is associated with the pace of cortical network development over the first three years of life
Tooley, U.; Latham, A.; Kenley, J. K.; Alexopoulos, D.; Smyser, T.; Warner, B. B.; Shimony, J. S.; Neil, J. J.; Luby, J. L.; Barch, D. M.; Rogers, C. E.; Smyser, C. D.
10.1101/2023.08.18.552639 — neuroscience — Posted on 2023-08-21
1651 Linking cognitive integrity to working memory dynamics in the aging human brain
Monov, G.; Stein, H.; Klock, L.; Gallinat, J.; Kuehn, S.; Lincoln, T.; Krkovic, K.; Murphy, P. R.; Donner, T. H.
10.1101/2023.08.18.553840 — neuroscience — Posted on 2023-08-21
1655 Progressive plasticity during colorectal cancer metastasis
Moorman, A.; Cambuli, F.; Benitez, E.; Jiang, Q.; Xie, Y.; Mahmoud, A.; Lumish, M.; Hartner, S.; Balkaran, S.; Bermeo, J.; Asawa, S.; Firat, C.; Saxena, A.; Luthra, A.; Sgambati, V.; Luckett, K.; Wu, F.; Li, Y.; Yi, Z.; Masilionis, I.; Soares, K.; Pappou, E.; Yaeger, R.; Kingham, P.; Jarnagin, W.; Paty, P.; Weiser, M. R.; Mazutis, L.; D'Angelica, M.; Shia, J.; Garcia-Aguilar, J.; Nawy, T.; Hollman, T.; Chaligne, R.; Sanchez-Vega, F.; Sharma, R.; Pe'er, D.; Ganesh, K.
10.1101/2023.08.18.553925 — cancer biology — Posted on 2023-08-21
1656 Multiplex imaging of localized prostate tumors reveals changes in mast cell type composition and spatial organization of AR-positive cells in the tumor microenvironment
Eksi, S. E.; Ak, C.; Sayar, Z.; Thibault, G.; Burlingame, E.; Eng, J.; Chitsazan, A.; Adey, A.; Boniface, C.; Spellman, P. T.; Thomas, G. V.; Kopp, R.; Demir, E.; Chang, Y. H.; Stavrinides, V.
10.1101/2023.08.18.553854 — cancer biology — Posted on 2023-08-21
1660 Chemokine receptor 5 signaling in PFC mediates stress susceptibility in female mice
Lin, H.-Y.; Cathomas, F.; Li, L.; Cuttoli, R. D.-d.; Guevara, C.; Sevim Bayrak, C.; Wang, Q.; Gupta, S.; Chan, K. L.; Shimo, Y.; Parise, L. F.; Yuan, C.; Aubry, A.; Chen, F.; Wong, J.; Morel, C.; Huntley, G. W.; Zhang, B.; Russo, S.; Wang, J.
10.1101/2023.08.18.553789 — animal behavior and cognition — Posted on 2023-08-21
1666 An extracellular vesicle delivery platform based on the PTTG1IP protein
Martin Perez, C.; Liang, X.; Gupta, D.; Conceicao, M.; Mäger, I.; EL Andaloussi, S.; Wood, M. J. A.; Roberts, T. C.
10.1101/2023.08.18.553853 — molecular biology — Posted on 2023-08-21
1671 Digging deeper into pain - an ethological behavior assay correlating well-being in mice with human pain experience.
Pattison, L. A.; Cloake, A.; Chakrabarti, S.; Hilton, H.; Rickman, R. H.; Higham, J. P.; Meng, M. Y.; Paine, L. W.; Qiu, L.; Ritoux, A.; Bulmer, D. C.; Callejo, G.; Smith, E. S. J.
10.1101/2023.08.18.553862 — neuroscience — Posted on 2023-08-21
1672 Central and peripheral tau retention modulated by an anti-tau antibody.
Solorzano, A.; Brady, M.; Bhatt, N.; Peterson, A.; Burgess, B.; Leyva, H.; Puangmalai, N.; Jerez, C.; Wood, R.; Kayed, R.; Deane, R.
10.1101/2023.08.17.553682 — physiology — Posted on 2023-08-21
1674 Noncoding genetic variation in ISPD distinguishes gamecocks from nongame chickens
Bendesky, A.; Brew, J.; Francis, K. X.; Tello Corbetto, E. F.; Gonzalez Ariza, A.; Nogales Baena, S.; Shimmura, T.
10.1101/2023.08.16.553562 — evolutionary biology — Posted on 2023-08-21
1677 KDM6A facilitates Xist upregulation at the onset of X inactivation
Lin, J.; Zhang, J.; Ma, L.; Fang, H.; Groneck, C.; Filippova, G. N.; Deng, X.; Ma, W.; Disteche, C. M.; Berletch, J. B.
10.1101/2023.08.16.553617 — molecular biology — Posted on 2023-08-21
1678 The role of neutrophil typing in homeostatic resilience protective model of inflammatory preconditioning
Li, L.; Zhang, X.; Yu, H.; Yan, C.; Sun, J.; Qi, Y.; Gou, Y.; Zhang, M.; Wang, S.; Li, H.; Nie, W.; Wang, R.; Jiang, J.; Gao, F.; Li, X.; Shi, Q.; Song, L.; Wang, F.; Xu, X.; Sun, W.
10.1101/2023.08.17.553795 — immunology — Posted on 2023-08-21
1679 Antimicrobial Activity of NK Cells to Trypanosoma cruzi Infected Human Primary Keratinocytes
Kroh, K.; Barton, J.; Fehling, H.; Lotter, H.; Volkmer, B.; Greinert, R.; Mhamdi-Ghodbani, M.; Vanegas Ramirez, A.; Jacobs, T.; Galvez, R.
10.1101/2023.08.17.553656 — immunology — Posted on 2023-08-21
1682 Magnetic voluntary head-fixation in transgenic rats enables lifetime imaging of hippocampal neurons
Rich, P. D.; Thiberge, S. Y.; Scott, B. B.; Guo, C.; Tervo, D. G.; Brody, C.; Karpova, A. Y.; Daw, N. D.; Tank, D. W.
10.1101/2023.08.17.553594 — neuroscience — Posted on 2023-08-21
1684 Genetic and brain similarity independently predict childhood anthropometrics and socioeconomic markers
Dahl, A.; Eilertsen, E. M.; Rodriguez-Cabello, S. F.; Norbom, L.; Tandberg, A. D.; Leonardsen, E.; Lee, S. H.; Ystrom, E.; Tamnes, C. K.; Alnaes, D.; Westlye, L. T.
10.1101/2023.08.18.553837 — neuroscience — Posted on 2023-08-21
1686 Validation of the sleep EEG headband ZMax
Jafarzadeh Esfahani, M.; D. Weber, F.; Boon, M.; Anthes, S.; Almazova, T.; van Hal, M.; Keuren, Y.; Heuvelmans, C.; Simo, E.; Bovy, L.; Adelhofer, N.; ter Avest, M. M.; Perslev, M.; ter Horst, R.; Harous, C.; Sundelin, T.; Axelsson, J.; Dresler, M.
10.1101/2023.08.18.553744 — neuroscience — Posted on 2023-08-21
1687 Multi-Site Statistical Mapping of Along-Tract Microstructural Abnormalities in Bipolar Disorder with Diffusion MRI Tractometry
Nabulsi, L.; Qamar, B.; McPhilemy, G.; Martyn, F. M.; Roberts, G.; Hallahan, B.; Dannlowski, U.; Kircher, T.; Haarman, B.; Mitchell, P. B.; McDonald, C.; Cannon, D. M.; Andreassen, O. A.; Ching, C. R. K.; Thompson, P. M.
10.1101/2023.08.17.553762 — neuroscience — Posted on 2023-08-21
1689 The isoflavonoid brazilin inhibits viability and cell migration in breast cancer cells
Hernandez-Moreno, A.; Nava-Tapia, D. A.; Bello-Martinez, J.; Olea-Flores, M.; Hernandez-Moreno, T.; Zuniga-Eulogio, M. D.; Navarro-Tito, N.
10.1101/2023.08.17.553723 — cancer biology — Posted on 2023-08-21
1690 An integrative framework of stochastic variational variable selection for joint analysis of multi-omics microbiome data
Dang, T.; Fuji, Y.; Kumaishi, K.; Usui, E.; Kobori, S.; Sato, T.; Toda, Y.; Sakurai, K.; Yamasaki, Y.; Tsujimoto, H.; Hirai, M. Y.; Ichihashi, Y.; Iwata, H.
10.1101/2023.08.18.553796 — bioinformatics — Posted on 2023-08-21
1692 Proteome-Wide Association Studies for Blood Lipids and Comparison with Transcriptome-Wide Association Studies
Zhang, D.; Gao, B.; Feng, Q.; Manichaikul, A. W.; Peloso, G. M.; Tracy, R.; Durda, P.; Taylor, K.; Liu, Y.; Johnson, W. C.; Gabriel, S.; Gupta, N.; Smith, J. D.; Aguet, F.; Ardlie, K. G.; Blackwell, T. W.; Gerszten, R. E.; Rich, S. S.; Rotter, J. I.; Scott, L.; Zhou, X.; Lee, S.
10.1101/2023.08.17.553749 — genomics — Posted on 2023-08-21
1694 Identification of human skin microbiome odorants that manipulate mosquito landing behavior - towards engineering a repellent skin flora
Coutinho-Abreu, I. V.; Jamshidi, O.; Raban, R.; Atabakhsh, K.; Merriman, J. A.; Fischbach, M. A.; Akbari, O. S.
10.1101/2023.08.19.553996 — zoology — Posted on 2023-08-21
1696 Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling
Huang, B.; Abedi, M.; Ahn, G.; Coventry, B.; Sappington, I.; Wang, R.; Schlichthaerle, T.; Zhang, J. Z.; Wang, Y.; Goreshnik, I.; Chiu, C. W.; Chazin-Gray, A.; Chan, S.; Gerben, S.; Murray, A.; Wang, S.; O'Neill, J.; Yeh, R.; Misquith, A.; Wolf, A.; Tomasovic, L. M.; Piraner, D. I.; Gonzalez, M. J. D.; Bennett, N. R.; Venkatesh, P.; Ahlrichs, M.; Dobbins, C.; Yang, W.; Wang, X.; Vafeados, D.; Mout, R.; Shivaei, S.; Cao, L.; Carter, L.; Stewart, L.; Spangler, J. B.; Bernardes, G. J. L.; Roybal, K. T.; Greisen, P. J.; Li, X.; Bertozzi, C.; Baker, D.
10.1101/2023.08.19.553321 — synthetic biology — Posted on 2023-08-21
1697 Longevity Bottlenecks
Florea, M.; Hamalainen, M.; Seebold, P.; Cheng, N.; Murray, P.; Colville, A. J.; Zheng, S.; Ingham, D.; Kantelal, R.; De Sicilia, R.
10.1101/2023.08.18.553936 — scientific communication and education — Posted on 2023-08-21
1698 Characterization of Tryptophan Oxidation Affecting D1 Degradation by FtsH in the Photosystem II Quality Control of Chloroplasts
Kato, Y.; Kuroda, H.; Ozawa, S.-I.; Saito, K.; Dogra, V.; Scholz, M.; Zhang, G.; de Vitry, C.; Ishikita, H.; Kim, C.; Hippler, M.; Takahashi, Y.; Sakamoto, W.
10.1101/2023.04.20.537607 — plant biology — Posted on 2023-08-20
1700 The phosphorylation landscape of infection-related development by the rice blast fungus
Cruz-Mireles, N.; Oses-Ruiz, M.; Derbyshire, P.; Jegousse, C.; Ryder, L. S.; Bautista, M.-J.; Eseola, A. B.; Tang, B.; Yan, X.; Ma, W.; Findlay, K. C.; Were, V.; MacLean, D.; Talbot, N. J.; Menke, F. L. H.
10.1101/2023.08.19.553964 — plant biology — Posted on 2023-08-20
1705 Host factor PLAC8 is required for pancreas infection by SARS-CoV-2
Ibarguen Gonzalez, L.; Heller, S.; DeDiego, M. L.; Lopez-Garcia, D.; Gomez-Valero, A. M.; Barth, T. F.; Gallego, P.; Fernandez-Cardenas, I.; Alzate-Pinol, S.; Crespi, C.; Mena-Guerrero, J. A.; Cisneros-Barroso, M. E.; Ugalde, A. P.; Bretones, G.; Steenblock, C.; Kleger, A.; Barcelo, C.
10.1101/2023.08.18.553908 — cell biology — Posted on 2023-08-21
1707 Tracing back primed resistance in cancer via sister cells
Dai, J.; Zheng, S.; Falco, M. M.; Bao, J.; Eriksson, J.; Pikkusaari, S.; Forsten, S.; Jiang, J.; Wang, W.; Gao, L.; Perez-Villatoro, F.; Dufva, O.; Saeed, K.; Wang, Y.; Amiryousefi, A.; Färkkilä, A.; Mustjoki, S.; Kauppi, L.; Tang, J.; Vähärautio, A.
10.1101/2022.07.06.498926 — cancer biology — Posted on 2023-08-21
1709 β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor
Daly, C.; Guseinov, A. A.; Hahn, H.; Wright, A.; Tikhonova, I.; Thomsen, A. R. B.; Plouffe, B.
10.1101/2023.04.01.535208 — cell biology — Posted on 2023-08-21
1710 Synaptic mechanisms for associative learning in the cerebellar nuclei
Broersen, R.; Albergaria, C.; Carulli, D.; Carey, M. R.; Canto, C. B.; De Zeeuw, C. I.
10.1101/2022.10.28.514163 — neuroscience — Posted on 2023-08-21
1711 A high-resolution gene expression atlas of the medial and lateral domains of the gynoecium of Arabidopsis
Luna-Garcia, V.; Bernal-Gallardo, J. J.; Rethoret-Pasty, M.; Pasha, A.; Provart, N. J.; de Folter, S.
10.1101/2023.08.19.553994 — plant biology — Posted on 2023-08-21
1714 Evidence for increased fitness of a plant pathogen conferred by epigenetic variation
Gopalan-Nair, R.; Coissac, A.; Legrand, L.; Lopez-Roques, C.; Pecrix, Y.; Vandecasteele, C.; BOUCHEZ, O.; Barlet, X.; Lanois, A.; Givaudan, A.; Brillard, J.; Genin, S.; GUIDOT, A.
10.1101/2023.08.16.553519 — evolutionary biology — Posted on 2023-08-21
1715 A data-driven evaluation of Arabidopsis-centric research and the model species concept
Palande, S.; Arsenault, J.; Basurto-Lozada, P.; Bleich, A.; Brown, B. N. I.; Buysse, S. F.; Connors, N. A.; Das Adhikari, S.; Dobson, K. C.; Guerra-Castillo, F. X.; Guerrero-Carrillo, M. F.; Harlow, S.; Herrera-Orozco, H.; Hightower, A. T.; Izquierdo, P.; Jacobs, M.; Johnson, N. A.; Leuenberger, W.; Lopez-Hernandez, A.; Luckie-Duque, A.; Martinez-Avila, C.; Mendoza-Galindo, E.; Plancarte, D.; Schuster, J. M.; Shomer, H.; Sitar, S. C.; Steensma, A. K.; Thomson, J. E.; Villasenor-Amador, D.; Waterman, R.; Webster, B. M.; Whyte, M.; Zorrilla-Azcue, S.; Montgomery, B. L.; Husbands, A. Y.; Krishnan
10.1101/2023.08.20.554029 — plant biology — Posted on 2023-08-21
1716 Combined Mek inhibition and Pparg activation Eradicates Muscle Invasive Bladder cancer in a Mouse Model of BBN-induced Carcinogenesis
Tate, T.; Plumber, S. A.; Al-Ahmadie, H.; Chen, X.; Choi, W.; Lu, C.; Viny, A. D.; Batourina, E.; Gretarsson, K.; Alija, B.; Molotkov, A.; Wiessner, G.; Mckiernan, J. M.; McConkey, D. J.; Dinney, C.; Czerniak, B.; Mendelsohn, C. L.
10.1101/2023.08.19.553961 — cancer biology — Posted on 2023-08-21
1717 SAW: An efficient and accurate data analysis workflow for Stereo-seq spatial transcriptomics
Gong, C.; Li, S.; Wang, L.; Zhao, F.; Fang, S.; Yuan, D.; Zhao, Z.; He, Q.; Li, M.; Liu, W.; Li, Z.; Xie, H.; Liao, S.; Chen, A.; Zhang, Y.; Li, Y.; Xu, X.
10.1101/2023.08.20.554064 — bioinformatics — Posted on 2023-08-21
1721 Acquired stress resilience through bacteria-to-nematode horizontal gene transfer
Pandey, T.; Kalluraya, C.; Wang, B.; Xu, T.; Huang, X.; Guang, S.; Daugherty, M. D.; Ma, D. K.
10.1101/2023.08.20.554039 — genetics — Posted on 2023-08-21
1728 Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses
Vecchio, F.; Carre, A.; Korenkov, D.; Zhou, Z.; Apaolaza, P.; Tuomela, S.; Burgos-Morales, O.; Snowhite, I.; Perez-Hernandez, J.; Brandao, B.; Afonso, G.; Halliez, C.; Kaddis, J.; Kent, S. C.; Nakayama, M.; Richardson, S. J.; Vinh, J.; Verdier, Y.; Laiho, J.; Scharfmann, R.; Solimena, M.; Marinicova, Z.; Bismuth, E.; Lucidarme, N.; Sanchez, J.; Bustamante, C.; Gomez, P.; Buus, S.; the nPOD-Virus Working Group, ; You, S.; Pugliese, A.; Hyoty, H.; Rodriguez-Calvo, T.; Flodstrom-Tullberg, M.; Mallone, R.
10.1101/2023.08.19.553954 — immunology — Posted on 2023-08-21
1730 Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons
Bell, A. M.; Utting, C.; Hachisuka, J.; Dickie, A. C.; Kucharczyk, M. W.; Quillet, R.; Gutierrez-Mecinas, M.; Razlan, A. N. B.; Cooper, A. H.; Lan, Y.; Weir, G. A.; Bannister, K.; Watanabe, M.; Hoon, M. A.; Macaulay, I. C.; Denk, F.; Todd, A.
10.1101/2023.08.20.553715 — neuroscience — Posted on 2023-08-21
1731 Striatal dopamine release reflects a multi-factorial prediction error
Costa, K. M.; Raheja, N.; Mirani, J.; Sercander, C.; Schoenbaum, G.
10.1101/2023.08.19.553959 — neuroscience — Posted on 2023-08-21
1732 Local activation of CA1 pyramidal cells induces theta phase precession
Sloin, H.; Spivak, L.; Levi, A.; Gattegno, R.; Someck, S.; Stark, E.
10.1101/2023.08.19.553985 — neuroscience — Posted on 2023-08-21
1733 BundleCleaner: Unsupervised Denoising and Subsampling of Diffusion MRI-Derived Tractography Data
Feng, Y.; Chandio, B. Q.; Villalon-Reina, J. E.; Thomopoulos, S. I.; Joshi, H.; Nair, G.; Joshi, A. A.; Venkatasubramanian, G.; John, J. P.; Thompson, P. M.
10.1101/2023.08.19.553990 — neuroscience — Posted on 2023-08-21
1734 Software Package for Transcranial Magnetic Stimulation Coil and Coil Array Analysis and Design
Morales, L.; Wartman, W. A.; Ferreira, J.; Miles, A.; Daneshzand, M.; Lu, H. A.; Nummenmaa, A.; Deng, Z.-D.; Makaroff, S. N.
10.1101/2023.08.20.554037 — neuroscience — Posted on 2023-08-21
1736 An ancient role for the CYP73 gene family in t-cinnamic acid 4-hydroxylation, phenylpropanoid biosynthesis and embryophyte development
Knosp, S.; Kriegshauser, L.; Tatsumi, K.; Malherbe, L.; Wiedemann, G.; Bakan, B.; Kohchi, T.; Reski, R.; Renault, H.
10.1101/2023.08.20.551634 — plant biology — Posted on 2023-08-21
1737 A thrombus is formed by a gradient of platelet activation and procoagulant endothelium
CARMINITA, E.; TOURN, J.; CRESCENCE, L.; BROUILLY, N.; MERRILL-SKOLOFF, G.; MAZHARIAN, A.; DUBOIS, C.; Panicot-Dubois, L.
10.1101/2023.08.19.550692 — physiology — Posted on 2023-08-20
1739 Toxicokinetic Characterization of the Inter-Species Differences in 6PPD-Quinone Toxicity Across Seven Fish Species: Metabolite Identification and Semi-Quantification
Montgomery, D. J.; Ji, X.; Cantin, J.; Philibert, D.; Foster, G.; Selinger, S.; Jain, N.; Miller, J.; McIntyre, J.; de Jourdan, B.; Wiseman, S.; Hecker, M.; Brinkmann, M.
10.1101/2023.08.18.553920 — pharmacology and toxicology — Posted on 2023-08-20
1744 Neuronal SNCA transcription during Lewy body formation
Kon, T.; Forrest, S. L.; Lee, S.; Martinez Valbuena, I.; Li, J.; Nassir, N.; Uddin, M. J.; Lang, A. E.; Kovacs, G. G.
10.1101/2023.08.19.553427 — pathology — Posted on 2023-08-20
1745 T Cell-to-Stroma Enrichment (TSE) score: a gene expression metric that predicts response to immune checkpoint inhibitors in patients with urothelial cancer
Rijnders, M. M.; Nakauma-Gonzalez, J. A.; Robbrecht, D. G. J.; Gil-Jimenez, A.; Balcioglu, H. E.; Oostvogels, A. A. M.; Aarts, M. J. B.; Boormans, J. L.; Hamberg, P.; van der Heijden, M. S.; Szabados, B. E.; van Leenders, G. J. L. H.; Mehra, N.; Voortman, J.; Westgeest, H. M.; de Wit, R.; van der Veldt, A. A. M.; Debets, R.; Lolkema, M. P.
10.1101/2022.05.30.493997 — cancer biology — Posted on 2023-08-20
1751 Additively manufactured multiplexed electrochemical device (AMMED) for portable sample-to-answer detection
Khorrami Jahromi, A.; Siavash Moakhar, R.; Yedire, S. G.; Shieh, H.; Rosenflanz, K.; Bricks, A.; de Vries, J.; Lu, Y.; Shafique, H.; Strauss, J.; Mahshid, S.
10.1101/2023.08.17.553741 — bioengineering — Posted on 2023-08-20
1752 Acylation of MLKL impacts its function in necroptosis
Pradhan, A. J.; Chitkara, S.; Ramirez, R.; Monje-Galvan, V.; Sancak, Y.; Atilla-Gokcumen, G. E.
10.1101/2023.08.19.553906 — biochemistry — Posted on 2023-08-20
1753 Glucose intolerance induces anxiety-like behaviors independent of obesity and insulin resistance in a novel model of nutritional metabolic stress
Al-Onaizi, M.; Braysh, K.; Alkefeef, S.; Altarrah, D.; Dannoon, S.; Alasousi, D.; Adel, H.; Al-Ajmi, M.; Kandari, A.; Najem, R.; Nizam, R.; Williams, M. R.; John, S.; Thanaraj, T. A.; Ahmad, R.; Al-Hussaini, H.; Al-Mulla, F.; Alzaid, F.
10.1101/2023.08.17.553760 — animal behavior and cognition — Posted on 2023-08-20
1756 Insights into RAG evolution from the identification of "missing link" family A RAGL transposons
Martin, E. C.; Le Targa, L.; Tsakou-Ngouafo, L.; Fan, T.-P.; Lin, C.-Y.; Xiao, J.; Su, Y.-H.; Petrescu, A.-J.; Pontarotti, P.; Schatz, D. G.
10.1101/2023.08.20.553239 — evolutionary biology — Posted on 2023-08-20
1761 Targeting mosquito X-chromosomes reveals complex transmission dynamics of sex ratio distorting gene drives
Haber, D. A.; Arien, Y.; Lamdan, L. B.; Alcalay, Y.; Zecharia, C.; Krsticevic, F.; Yonah, E. S.; Avraham, R. D.; Windbichler, N.; Papathanos, P. A.
10.1101/2023.08.20.554004 — synthetic biology — Posted on 2023-08-20
1762 One-pot chemo-enzymatic synthesis and one-step recovery of homogeneous long-chain polyphosphates from microalgal biomass
Lin, Y.-H.; Nishikawa, S.; Jia, T. Z.; Yeh, F.-I.; Khusnutdinova, A.; Yakunin, A. F.; Fujishima, K.; Wang, P.-H.
10.1101/2023.08.19.553819 — synthetic biology — Posted on 2023-08-20
1768 Molecular blueprints of the Langya virus attachment and fusion glycoproteins
Wang, Z.; McCallum, M.; Yan, L.; Sharkey, W.; Park, Y.-J.; Dang, H. V.; Amaya, M.; Person, A.; Broder, C. C.; Veesler, D. J.
10.1101/2023.08.20.554025 — biochemistry — Posted on 2023-08-20
1770 Structural framework for the understanding spectroscopic and functional signatures of the cyanobacterial Orange Carotenoid Protein families
Sluchanko, N. N.; Maksimov, E. G.; Slonimskiy, Y. B.; Varfolomeeva, L. A.; Bukhanko, A. Y.; Egorkin, N. A.; Tsoraev, G. V.; Khrenova, M. G.; Ge, B.; Qin, S.; Boyko, K. M.; Popov, V. O.
10.1101/2023.08.20.554024 — biochemistry — Posted on 2023-08-20
1778 Artificial Intelligence Helps to Predict Recurrence and Mortality for Prostate Cancer using Histology Images
Eminaga, O.; Saad, F.; Tian, Z.; Wolffgang, U.; Karakiewicz, P. I.; Ouellet, V.; Azzi, F.; Spieker, T.; Helmke, B. M.; Graefen, M.; Jiang, X.; Xing, L.; Witt, J. H.; Trudel, D.; Leyh-Bannurah, S.-R.
10.1101/2023.07.27.550781 — pathology — Posted on 2023-08-20
1780 Differences in Oligomerization of the SARS-CoV-2 Envelope Protein, Poliovirus VP4, and HIV Vpu
Townsend, J. A.; Fapohunda, O.; Wang, Z.; Pham, H.; Taylor, M. T.; Kloss, B.; Park, S. H.; Opella, S. J.; Aspinwall, C. A.; Marty, M. T.
10.1101/2023.08.18.553902 — biophysics — Posted on 2023-08-20
1781 Characterization and super-resolution imaging of small tau aggregates in human samples.
Boken, D.; Cox, D.; Burke, M.; Lam, J. Y. L.; Katsinelos, T.; Danial, J. S. H.; McEwan, W. A.; Rowe, J.; Klenerman, D.
10.1101/2023.06.12.544575 — biochemistry — Posted on 2023-08-20
1782 Genetic architectures of floral pigment and patterning in hybrid monkeyflowers
Cooley, A. M.; Schlutius, C.; Matthews, M.; Zheng, X.; Thomas, D.; Edger, P.; Platts, A.; George, L.; Williams, A.; LaFountain, A.; Hundley, D.; Yuan, Y.-w.; Twyford, A. D.; Puzey, J. D.
10.1101/2022.04.29.490035 — genetics — Posted on 2023-08-20
1785 Expanded diversity of novel hemoplasmas in rare and undersampled Neotropical bats
Volokhov, D.; Lock, L.; Dyer, K.; DeAnglis, I.; Andrews, B.; Simonis, M.; Stockmaier, S.; Carter, G.; Downs, C.; Fenton, B.; Simmons, N. B.; Becker, D.
10.1101/2023.06.05.543748 — microbiology — Posted on 2023-08-20
1787 Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations
Solis, E. M.; Good, L. B.; Vazquez, R. G.; Patnaik, S.; Hernandez-Reynoso, A. G.; Ma, Q.; Angulo, G.; Dobariya, A.; Cogan, S. F.; Pancrazio, J. J.; Pascual, J. M.; Jakkamsetti, V.
10.1101/2023.06.05.543611 — neuroscience — Posted on 2023-08-20
1788 The Selenoproteome as a dynamic response mechanism to oxidative stress in methanogenic communities
Kleikamp, H. B. C.; Jaramillo, P. A. P.; Kofoed, M. V. W.; Papacharalampos, G.; Bentien, A.; Nielsen, J. L.
10.1101/2023.08.14.549203 — microbiology — Posted on 2023-08-20
1792 Clonal and Scalable Endothelial Progenitor Cell Lines from Human Pluripotent Stem Cells
Lee, J.; Sterberg, H.; Bignone, P. A.; Murai, J.; Malik, N. N.; West, M. D.; Larocca, D.
10.1101/2023.08.19.553753 — cell biology — Posted on 2023-08-20
1793 Acto3D: user- and budget-friendly software for multichannel high-resolution three-dimensional imaging
Takeshita, N.; Sakaki, S.; Saba, R.; Inoue, S.; Nishikawa, K.; Ueyama, A.; Matsuo, K.; Shigeta, M.; Nakajima, Y.; Kobayashi, D.; Yamazaki, H.; Yamada, K.; Iehara, T.; Yashiro, K.
10.1101/2023.08.18.553473 — developmental biology — Posted on 2023-08-20
1794 Exploring high-quality microbial genomes by assembling short-reads with long-range connectivity
Zhang, Z.; Xiao, J.; Wang, H.; Yang, C.; Yufen, H.; Yue, Z.; Chen, Y.; Han, L.; Ying, K.; Lu, A.; Fang, X.; Zhang, L.
10.1101/2022.09.07.506963 — genomics — Posted on 2023-08-20
1795 Dynamics of chromatin accessibility during human first-trimester neurodevelopment
Mannens, C. C. A.; Hu, L.; Lonnerberg, P.; Schipper, M.; Reagor, C.; Li, X.; He, X.; Barker, R. A.; Sundstrom, E.; Posthuma, D.; Linnarsson, S.
10.1101/2023.08.18.553878 — developmental biology — Posted on 2023-08-20
1797 Protein Kinase A is Functional Component of Focal Adhesions
Kang, M.; Senatore, A. J.; Naughton, H.; Beltman, R. J.; Herppich, A. A.; Pflum, M. K. H.; Howe, A. K.
10.1101/2023.08.18.553932 — cell biology — Posted on 2023-08-20
1798 Neuroendocrine control of synaptic transmission by PHAC-1 in C. elegans.
Stratigi, A.; Soler-Garcia, M.; Krout, M.; Shukla, S.; de Bono, M.; Richmond, J. E.; laurent, p.
10.1101/2023.08.19.553960 — neuroscience — Posted on 2023-08-20
1800 Local translation is required for sustained circuit integrity in impaired Wallerian degeneration
Paglione, M.; Restivo, L.; Zakhia, S.; Llobet Rosell, A.; Terenzio, M.; Neukomm, L. J.
10.1101/2023.08.18.553870 — neuroscience — Posted on 2023-08-20
1801 Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs
Lyu, H.; Yuan, G.; Liu, X.; Wang, X.; Geng, S.; Xia, T.; Zhou, X.; Li, Y.; Hu, X.; Shi, Y.
10.1101/2023.06.04.543629 — immunology — Posted on 2023-08-20
1803 Non-Markovian memory in a bacterium
Joshi, K.; Ziegler, K. F.; Roy, S.; Wright, C. S.; Gandhi, R.; Stonecipher, J.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.05.27.542601 — biophysics — Posted on 2023-08-20
1805 IST1 regulates select endosomal recycling pathways
Clippinger, A. K.; Naismith, T. V.; Yoo, W.; Jansen, S.; Kast, D.; Hanson, P. I.
10.1101/2023.07.31.551359 — cell biology — Posted on 2023-08-20
1808 Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and psychiatric disease
Herborg, F.; Konrad, L. K.; Pugh, C. F.; Delignat-Lavaud, B.; Ratner, C.; Awadallah, N.; Pino, J. A.; Berlin, F.; Rickhag, M.; Holst, B.; Woldbye, D.; Torres, G.; Trudeau, L.-E.; Gether, U.
10.1101/2023.08.17.553695 — neuroscience — Posted on 2023-08-20
1813 Voyager: exploratory single-cell genomics data analysis with geospatial statistics
Moses, L.; Einarsson, P. H.; Jackson, K. C.; Luebbert, L.; Booeshaghi, A. S.; Antonsson, S. E.; Bray, N.; Melsted, P.; Pachter, L.
10.1101/2023.07.20.549945 — bioinformatics — Posted on 2023-08-20
1814 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting
Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.
10.1101/2022.06.23.497372 — bioengineering — Posted on 2023-08-20
1815 Mapping Human Tissues with Highly Multiplexed RNA in situ Hybridization
Kalhor, K.; Chen, C.-j.; Lee, H. S.; Cai, M.; Nafisi, M.; Que, R.; Palmer, C.; Yuan, Y.; Zhang, Y.; Song, J.; Knoten, A.; Lake, B.; Gaut, J.; Keene, D.; Lein, E.; Kharchenko, P.; Chun, J.; Jain, S.; Fan, J.-B.; Zhang, K.
10.1101/2023.08.16.553610 — genomics — Posted on 2023-08-19
1817 Foraging on host synthesized metabolites enables the bacterial symbiont Snodgrassella alvi to colonize the honey bee gut
Quinn, A.; El Chazli, Y.; Escrig, S.; Daraspe, J.; Neuschwander, N.; McNally, A.; Genoud, C.; Meibom, A.; Engel, P.
10.1101/2023.01.23.524906 — microbiology — Posted on 2023-08-20
1821 Difference in Kernel Shape and Endocarp Anatomy Promote Dehiscence in Pistachio Endocarp
Zhang, S.; WANG, M.; Chernikova, A.; Eagle, S.; Bedell, K. M.; Nguyen, K.; Blanco-Ulate, B.; Jernstedt, J.; Drakakaki, G.
10.1101/2023.08.18.553428 — plant biology — Posted on 2023-08-19
1823 Enriched atlas of lncRNA and protein-coding genes for the GRCg7b chicken assembly and its functional annotation across 47 tissues.
Degalez, F.; Charles, M.; Foissac, S.; Zhou, H.; Guan, D.; Fang, L.; Klopp, C.; Allain, C.; Lagoutte, L.; Lecerf, F.; Acloque, H.; Giuffra, E.; Pitel, F.; Lagarrigue, S.
10.1101/2023.08.18.553750 — genomics — Posted on 2023-08-19
1826 Double open syntaxin and UNC-18 P334A mutation leads to excitatory-inhibitory imbalance and impairs multiple aspects of C. elegans behavior
Huang, M.; Wang, Y.; Chow, C. H.; Stepien, K.; Indrawinata, K.; Argiropoulos, P.; Xie, X.; Sugita, K.; Tien, C.-W.; Lee, S.; Monnier, P. P.; Rizo, J.; Gao, S.; Sugita, S.
10.1101/2023.08.18.553709 — neuroscience — Posted on 2023-08-19
1827 Transcriptional Profiles of Non-neuronal and Immune Cells in Mouse Trigeminal Ganglia
Mecklenburg, J.; Shein, S. A.; Hovhannisyan, A. H.; Zou, Y.; Lai, Z.; Ruparel, S.; Tumanov, A. V.; Akopian, A. N.
10.1101/2023.08.18.553897 — neuroscience — Posted on 2023-08-19
1830 Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice
Matalon, S.; Yu, Z.; Dubey, S.; Ahmad, I.; Stephens, E. M.; Alishlash, A. S.; Meyers, A.; Cossar, D.; Stewart, D.; Acosta, E. P.; Kojima, K.; Jilling, T.; Mobley, J. A.
10.1101/2023.08.17.553717 — physiology — Posted on 2023-08-19
1831 Air Pollution Aggravates Renal Ischemia-Reperfusion-Induced Acute Kidney Injury
Sanches, T. R.; Parra, A. C.; Sun, P.; Graner, M.; Itto, L. Y. U.; Butter, L.; Claessen, N.; Roelofs, J. J. T. H.; Florquin, S.; Veras, M. M.; Andrade, M. d. F.; Saldiva, P. H. N.; Kers, J.; Andrade, L.; Tammaro, A.
10.1101/2023.08.17.553734 — pathology — Posted on 2023-08-19
1838 Trigeminal innervation and tactile responses in mouse tongue
Zhang, L.; Nagel, M.; Olson, W. P.; Chesler, A. T.; O'Connor, D. H.
10.1101/2023.08.17.553449 — neuroscience — Posted on 2023-08-19
1844 Local CpG-Stat3 siRNA treatment improves antitumor effects of checkpoint inhibitors
Yu, H.; Zhang, C.; Huang, R.; Ren, L.; Zhang, J.; Kortylewski, M.; Swiderski, P.; Forman, S.
10.1101/2023.08.17.553571 — immunology — Posted on 2023-08-19
1845 A slc38a8 mouse model of FHONDA syndrome faithfully recapitulates the visual deficits of albinism without pigmentation defects
Guardia, A.; Fernandez, A.; Seruggia, D.; Chotard, V.; Sanchez-Castillo, C.; Kutsyr, O.; Sanchez-Saez, X.; Zurita, E.; Cantero, M.; Rebsam, A.; Cuenca, N.; Montoliu, L.
10.1101/2023.08.19.553949 — neuroscience — Posted on 2023-08-19
1846 Enlarged Perivascular Spaces are Associated with White Matter Injury, Brain Atrophy, Cognitive Decline and Markers of Inflammation in an Autosomal Dominant Vascular Neurodegenerative Disease (CADASIL)
Karvelas, N.; Oh, B.; Wang, E.; Cobigo, Y.; Tsuei, T.; Fitzsimons, S.; Ehrenberg, A.; Geschwind, M.; Schwartz, D.; Kramer, J.; Ferguson, A. R.; Miller, B. L.; Silbert, L.; Rosen, H.; Elahi, F. M.
10.1101/2023.08.17.553732 — neuroscience — Posted on 2023-08-19
1847 Bioengineering of a human innervated cardiac muscle model
Schneider, L. V.; Bao, G.; Methi, A.; Jensen, O.; Schmoll, K. A.; Setya, M. G.; Sakib, M. S.; Fahud, A. L.; Brockmoeller, J.; Fischer, A.; Liaw, N. Y.; Zimmermann, W.-H.; Zafeiriou, M.-P.
10.1101/2023.08.18.552653 — bioengineering — Posted on 2023-08-19
1849 Tip60-mediated Rheb acetylation links palmitic acid with mTORC1 activation and insulin resistance
Zhao, Z.; Chen, Q.; Xiang, X.; Dai, W.; Fang, W.; Cui, K.; Li, B.; Liu, Q.; Liu, Y.; Shen, Y.; Li, Y.; Xu, W.; Mai, K.; Ai, Q.
10.1101/2023.08.18.553816 — cell biology — Posted on 2023-08-19
1851 Comprehensive Interrogation of Synthetic Relationships in the Human DNA Damage Response
Fielden, J.; Siegner, S. M.; Gallagher, D. N.; Schroeder, M.; Dello Stritto, M. R.; Kobel, L.; Schlapansky, M.; Cejka, P.; Jost, M.; Corn, J. E.
10.1101/2023.08.18.553865 — cell biology — Posted on 2023-08-19
1852 Development of Polarity-Reversed Endometrial Epithelial Organoids
Ahmad, V.; Yeddulaa, S. G. R.; Teluga, B. P.; Spencer, T. E.; Kelleher, A. M.
10.1101/2023.08.18.553918 — cell biology — Posted on 2023-08-19
1853 BioE3 enables the identification of bona fide targets of E3 ligases
Barroso-Gomila, O.; Merino-Cacho, L.; Muratore, V.; Perez, C.; Taibi, V.; Maspero, E.; Azkargorta, M.; Iloro, I.; Trulsson, F.; Vertegaal, A. C. O.; Mayor, U.; Elortza, F.; Polo, S.; Barrio, R.; Sutherland, J. D.
10.1101/2023.08.18.553883 — cell biology — Posted on 2023-08-19
1855 Nanopores reveal the stoichiometry of single oligo-adenylates produced by type III CRISPR-Cas
Fuentenebro-Navas, D.; Steens, J. A.; De Lannoy, C.; Noordijk, B.; de Ridder, D.; Staals, R. H. J.; Schmid, S.
10.1101/2023.08.18.553839 — biophysics — Posted on 2023-08-19
1856 2D cell culture on soft hydrogel drives an endoplasmic reticulum stress-dependent S quiescence underlying molecular traits of pulmonary basal cells
Laval, P.-A.; Piecyk, M.; Le Guen, P.; Ilie, M.; Fauvre, J.; Coste, I.; Renno, T.; Aznar, N.; Ansieau, S.; Hadji, C.; Migdal, C.; Duret, C.; Bertolino, P.; Ferraro-Peyret, C.; Nicolas, A.; Chaveroux, C.
10.1101/2023.08.18.552093 — cell biology — Posted on 2023-08-19
1857 Thrombospondin-1 promotes fibro-adipogenic stromal expansion and contractile dysfunction of the diaphragm in obesity
Buras, E. D.; Woo, M.-S.; Verma, R. K.; Kondisetti, S. H.; Davis, C. S.; Claflin, D. R.; Converso-Baran, K.; Michele, D. E.; Brooks, S. V.; Chun, T.-H.
10.1101/2023.08.17.553733 — cell biology — Posted on 2023-08-19
1858 Multi-omics map revealed PPARalpha activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis
Gao, Y.; Huang, F.; Ruan, F.; Lai, D.; Zhang, Z.; Zhang, Y.; Zhu, J.; Lu, Y.; Shen, L.; He, J.; Liu, Y.; Fu, G.; Zhu, Y.; Shen, L.; Zhuang, L.
10.1101/2023.08.17.551936 — cell biology — Posted on 2023-08-19
1859 Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells
Dellorusso, P. V.; Proven, M. A.; Calero-Nieto, F. J.; Wang, X.; Mitchell, C. A.; Hartmann, F.; Amouzgar, M.; Favaro, P.; DeVilbiss, A. W.; Swann, J. W.; Ho, T. T.; Zhao, Z. W.; Bendall, S. C.; Morrison, S. J.; Gottgens, B.; Passegue, E.
10.1101/2023.08.17.553736 — cell biology — Posted on 2023-08-19
1860 The apoptotic, inflammatory, and fibrinolytic actions of vasoinhibin are in a motif different from its antiangiogenic HGR motif
Robles, J. P.; Zamora, M.; Garcia-Rodrigo, J. F.; Perez, A. L.; Bertsch, T.; Martinez de la Escalera, G.; Triebel, J.; Clapp, C.
10.1101/2023.08.18.553934 — cell biology — Posted on 2023-08-19
1861 Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria
Schweighofer, S. V.; Jans, D. C.; Keller-Findeisen, J.; Folmeg, A.; Bates, M.; Jakobs, S.
10.1101/2023.08.18.553869 — cell biology — Posted on 2023-08-19
1863 Identification and mapping of human lymph node stromal cell subsets by combining single-cell RNA sequencing with spatial transcriptomics.
Grasso, C.; Roet, J.; Gago de Graca, C.; Semmelink, J. F.; Remmerswaal, E.; Jongejan, A.; Moerland, P. D.; Mebius, R. E.; van Baarsen, L. G. M.
10.1101/2023.08.18.553530 — cell biology — Posted on 2023-08-19
1864 Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment
Sekar, T. V.; Elghonaimy, E.; Swancutt, K. L.; Diegeler, S.; Gonzalez, I.; Hamilton, C.; Leung, P. Q.; Meiler, J.; Martina, C. E.; Whitney, M.; Aguilera, T. A.
10.1101/2021.05.26.445719 — bioengineering — Posted on 2023-08-19
1865 Morphometry and mechanical instability at the onset of epithelial bladder cancer
Lampart, F. L.; Vetter, R.; Wang, Y.; Yamauchi, K. A.; Strohmeyer, N.; Meer, F.; Hussherr, M.-D.; Camenisch, G.; Seifert, H.-H.; Rentsch, C. A.; Le Magnen, C.; Mueller, D. J.; Bubendorf, L.; Iber, D.
10.1101/2023.08.17.553533 — cancer biology — Posted on 2023-08-19
1866 Alignment of spatial transcriptomics data using diffeomorphic metric mapping
Clifton, K.; Anant, M.; Aihara, G.; Atta, L.; Aimiuwu, O. K.; Kebschull, J. M.; Miller, M. I.; Tward, D.; Fan, J.
10.1101/2023.04.11.534630 — bioinformatics — Posted on 2023-08-19
1867 Molecular mechanism of dynein-dynactin activation by JIP3 and LIS1
Singh, K.; Lau, C.; Manigrasso, G.; Gama, J. B.; Gassmann, R.; Carter, A. P.
10.1101/2022.08.17.504273 — molecular biology — Posted on 2023-08-19
1868 Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
Moris, V. C.; Bruneau, L.; Berthe, J.; Heuskin, A.-C.; Penninckx, S.; Ritter, S.; Weber, U.; Durante, M.; Danchin, E. G. J.; Hespeels, B.; Van Doninck, K.
10.1101/2023.06.16.545282 — molecular biology — Posted on 2023-08-19
1869 Non-invasive Analysis of Peptidoglycan from Living Animals
Ocius, K. L.; Kolli, S. H.; Chorida, M. D.; Rutkowski, M. R.; Pires, M.
10.1101/2023.07.21.549941 — microbiology — Posted on 2023-08-19
1871 Metabolism of glucose and trehalose by cyclic pentose phosphate pathway is essential for effective immune response in Drosophila
Kazek, M.; Chodakova, L.; Lehr, K.; Strych, L.; Nedbalova, P.; McMullen, E.; Bajgar, A.; Simek, P.; Moos, M.; Dolezal, T.
10.1101/2023.08.17.553657 — immunology — Posted on 2023-08-19
1872 Aversive experience drives offline ensemble reactivation to link memories across days
Zaki, Y.; Pennington, Z. T.; Morales-Rodriguez, D.; Francisco, T. R.; LaBanca, A. R.; Dong, Z.; Lamsifer, S.; Segura, S. C.; Chen, H.-t.; Christenson Wick, Z.; Silva, A. J.; van der Meer, M.; Shuman, T.; Fenton, A.; Rajan, K.; Cai, D. J.
10.1101/2023.03.13.532469 — neuroscience — Posted on 2023-08-19
1878 Interface resistance of biomolecular condensates
Zhang, Y.; Pyo, A. G. T.; Jiang, Y.; Brangwynne, C. P.; Stone, H. A.; Wingreen, N. S.
10.1101/2022.03.16.484641 — biophysics — Posted on 2023-08-19
1883 A chromosome-level reference genome for the common octopus, Octopus vulgaris (Cuvier, 1797)
Destanovic, D.; Schultz, D. T.; Styfhals, R.; Cruz, F.; Gomez-Garrido, J.; Gut, M.; Gut, I.; Fiorito, G.; Simakov, O.; Alioto, T. S.; Ponte, G.; Seuntjens, E.
10.1101/2023.05.16.540928 — genomics — Posted on 2023-08-19
1884 Transposable element expression with variation in sex chromosome number supports a toxic Y effect on human longevity
Teoli, J.; Fablet, M.; Bardel, C.; Necsulea, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2023-08-19
1886 Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
Tissink, E.; Shadrin, A. A.; van der Meer, D.; Parker, N.; Hindley, G.; Roelfs, D.; Frei, O.; Fan, C. C.; Nagel, M.; Naerland, T.; Budisteanu, M.; Djurovic, S.; Westlye, L. T.; van den Heuvel, M.; Posthuma, D.; Kaufmann, T.; Dale, A. M.; Andreassen, O.
10.1101/2022.12.20.521181 — genetics — Posted on 2023-08-19
1888 The demographic history of the wild crop relative Brachypodium distachyon is shaped by distinct past and present ecological niches.
Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.
10.1101/2023.06.01.543285 — ecology — Posted on 2023-08-19
1890 Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation
Tundidor, I.; Seijo-Vila, M.; Blasco-Benito, S.; Rubert-Hernandez, M.; Moreno-Bueno, G.; Bindila, L.; Fernandez de la Rosa, R.; Guzman, M.; Sanchez-Garcia, C.; Perez-Gomez, E.
10.1101/2023.04.03.535417 — developmental biology — Posted on 2023-08-19
1891 Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells
Stephens, D. C.; Crabtree, A.; Beasley, H. K.; Garza-Lopez, E.; Neikirk, K.; Mungai, M.; Vang, L.; Vue, Z.; Vue, N.; Marshall, A. G.; Turner, K.; Shao, J.-q.; Murray, S. A.; Gaddy, J. A.; Wanjalla, C.; Davis, J.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541599 — cell biology — Posted on 2023-08-19
1892 Components of Isolated Skeletal Muscle Differentiated Through Antibody Validation
Stephens, D. C.; Mungai, M.; Crabtree, A.; Beasley, H. K.; Garza-Lopez, E.; Vang, L.; Neikirk, K.; Vue, Z.; Vue, N.; Marshall, A. G.; Turner, K.; Shao, J.-q.; Sarker, B.; Murray, S. A.; Gaddy, J. A.; Davis, J.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541600 — cell biology — Posted on 2023-08-19
1894 Creating Optimal Conditions for OPA1 isoforms by Western Blot in Muscle Tissue
Stephens, D. C.; Crabtree, A.; Beasley, H. K.; Garza-Lopez, E.; Mungai, M.; Neikirk, K.; Vang, L.; Vue, Z.; Vue, N.; Marshall, A. G.; Turner, K.; Shao, J.-q.; Murray, S. A.; Gaddy, J. A.; Wanjalla, C.; Davis, J.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541601 — cell biology — Posted on 2023-08-19
1896 Genetic validation of PfFKBP35 as an antimalarial drug target
Thommen, B. T.; Dziekan, J. M.; Achcar, F.; Tjia, S.; Passecker, A.; Buczak, K.; Gumpp, C.; Schmidt, A.; Rottmann, M.; Gruering, C.; Marti, M.; Bozdech, Z.; Brancucci, N. M. B.
10.1101/2022.12.09.519720 — molecular biology — Posted on 2023-08-19
1898 Development of genomic resources for cattails (Typha), a globally important macrophyte genus
Aleman, J. A.; Dorken, M. E.; Shafer, A.; Patel, T.; Volkova, P. A.; Freeland, J. R.
10.1101/2023.04.21.537876 — molecular biology — Posted on 2023-08-19
1899 Whole Genome Sequencing based Identification of Human Tuberculosis caused by Animal-lineage Mycobacterium orygis
Islam, M. R.; Sharma, M. K.; KhunKhun, R.; Shandro, C.; Sekirov, I.; Tyrell, G. J.; Soualhine, H.
10.1101/2023.02.27.530375 — microbiology — Posted on 2023-08-19
1900 Apoptotic signaling clears engineered Salmonella in an organ-specific manner
Abele, T. J.; Billman, Z. P.; Li, L.; Harvest, C. K.; Bryan, A. K.; Magalski, G. R.; Lopez, J. P.; Larson, H. N.; Yin, X.-M.; Miao, E. A.
10.1101/2023.05.06.539681 — immunology — Posted on 2023-08-19
1903 Causal role of the angular gyrus in insight-driven memory reconfiguration
Grob, A.-M.; Heinbockel, H.; Milivojevic, B.; Doeller, C.; Schwabe, L.
10.1101/2023.08.18.553803 — neuroscience — Posted on 2023-08-18
1904 Temporal regularities shape perceptual decisions and striatal dopamine signals
Fritsche, M.; Majumdar, A.; Strickland, L.; Liebana Garcia, S.; Bogacz, R.; Lak, A.
10.1101/2023.08.18.553829 — neuroscience — Posted on 2023-08-18
1905 A competitive disinhibitory network for robust optic flow processing in Drosophila
Erginkaya, M.; Cruz, T. L.; Brotas, M.; Steck, K.; Nern, A.; Torrao, F.; Varela, N.; Bock, D.; Reiser, M. B.; Chiappe, M. E.
10.1101/2023.08.06.552150 — neuroscience — Posted on 2023-08-19
1910 Proteomic and functional comparison between human induced and embryonic stem cells
Brenes, A. J.; Griesser, E.; Sinclair, L. V.; Davidson, L.; Prescott, A. R.; Singh, F.; Hogg, E. K. J.; Espejo-Serrano, C.; Jiang, H.; Yoshikawa, H.; Platani, M.; Swedlow, J.; Cantrell, D. A.; Lamond, A. I.
10.1101/2021.10.20.464767 — systems biology — Posted on 2023-08-19
1911 Cis-regulatory modes of Ultrabithorax inactivation in butterfly forewings
Tendolkar, A.; Mazo-Vargas, A.; Livraghi, L.; Hanly, J. J.; Van Horne, K. C.; Gilbert, L. E.; Martin, A.
10.1101/2023.08.18.553910 — genomics — Posted on 2023-08-18
1912 eQTL mapping in transgenic alpha-synuclein carrying Caenorhabditis elegans recombinant inbred line
Huang, Y.; Wang, Y. A.; van Sluijs, L.; Chen, Y.; Schoonerwoerd, S.; Tegelbeckers, V. I. P.; Vogels, D. H. J.; Riksen, J.; Kammenga, J. E.; Harvey, S. C.; Sterken, M. G.
10.1101/2023.08.18.553811 — genomics — Posted on 2023-08-18
1913 Massively Parallel Reporter Assay Confirms Regulatory Potential of hQTLs and Reveals Important Variants in Lupus and Other Autoimmune Diseases
Fu, Y.; Kelly, J. A.; Gopalakrishnan, J.; Pelikan, R. C.; Tessneer, K. L.; Pasula, S.; Grundahl, K.; Murphy, D. A.; Gaffney, P. M.
10.1101/2023.08.17.553722 — genomics — Posted on 2023-08-18
1914 Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q
SONTI, S.; Littleton, S. H.; Pahl, M. C.; Zimmerman, A. J.; Chesi, A.; Palermo, J.; Lasconi, C.; Brown, E. B.; Pippin, J. A.; Wells, A. D.; Balli, F. D.; Pack, A. I.; Gehrman, P. R.; Keen, A. C.; Grant, S. F.
10.1101/2023.08.17.553739 — genomics — Posted on 2023-08-18
1915 CryptoCEN: A Co-Expression Network for Cryptococcus neoformans reveals novel proteins involved in DNA damage repair
O'Meara, M. J.; Rapala, J. R.; Nichols, C. B.; Alexandre, C.; Billmyre, R. B.; Steenwyk, J. L.; Alspaugh, J. A.; O'Meara, T. R.
10.1101/2023.08.17.553567 — genetics — Posted on 2023-08-18
1916 Cooperation between bacteriocytes and endosymbionts drives function and development of symbiotic cells in mussel holobionts
Chen, H.; Li, M.; Zhong, Z.; Wang, M.; Lian, C.; Han, G.; Wang, H.; Zhou, L.; Zhang, H.; Cao, L.; LI, C.
10.1101/2023.08.18.553804 — ecology — Posted on 2023-08-18
1918 Purine biosynthesis pathways are required for myogenesisin Xenopus laevis
Dupperay, M.; Henriet, E.; Saint-Marc, C.; Boue-Grabot, E.; Daignan-Fornier, B.; Masse, K.; Pinson, B.
10.1101/2023.08.17.553788 — developmental biology — Posted on 2023-08-18
1920 Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI.
Kapustin, A. N.; Tsakali, S. S.; Whitehead, M.; Chennell, G.; Wu, M.-Y.; Molenaar, C.; Kutikhin, A.; Bogdanov, L.; Sinitsky, M.; Rubina, K.; Clayton, A.; Verweij, F. J.; Pegtel, D. M.; Zingaro, S.; Lobov, A.; Zainullina, B.; Owen, D.; Parsons, M.; Cheney, R. E.; Warren, D.; Humphries, M. J.; Iskratsch, T.; Holt, M.; Shanahan, C. M.
10.1101/2023.08.17.551257 — cell biology — Posted on 2023-08-18
1921 Integrative assessment of total and intact HIV-1 reservoir by a five-region multiplexed Rainbow digital PCR assay
Delporte, M.; van Snippenberg, W.; Blomme, E. E.; Rutsaert, S.; Verschoore, M.; De Smet, E.; De Scheerder, M.-A.; Gerlo, S.; Vandekerckhove, L.; Trypsteen, W.
10.1101/2023.08.18.553846 — molecular biology — Posted on 2023-08-18
1922 Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells
Long, Y.; Hwang, T.; Gooding, A. R.; Goodrich, K. J.; Vallery, T. K.; Rinn, J. L.; Cech, T. R.
10.1101/2023.08.17.553776 — molecular biology — Posted on 2023-08-18
1924 SPTF-3/SP1 orchestrates mitochondrial biogenesis upon ribosomal stress and acute starvation
Hermeling, J.; Pavlenko, V.; Herholz, M.; Baumaann, L.; Zecic, A.; Kukat, A.; Popovic, M.; Szczepanowska, K.; Cepeda Cores, E.; Vilchez, D.; Kurian, L.; Trifunovic, A.
10.1101/2023.08.18.553493 — molecular biology — Posted on 2023-08-18
1925 Temperate gut phages are prevalent, diverse, and predominantly inactive
Dahlman, S.; Avellaneda-Franco, L.; Kett, C.; Subedi, D.; Young, R. B.; Gould, J. A.; Rutten, E. L.; Gilliver, E. L.; Turkington, C. J.; Nezam-Abadi, N.; Grasis, J. A.; Lyras, D.; Edwards, R. A.; Forster, S. C.; Barr, J. J.
10.1101/2023.08.17.553642 — microbiology — Posted on 2023-08-18
1926 Co-Occurrence Network Analysis Reveals The Alterations Of The Skin Microbiome And Metabolome In Atopic Dermatitis Patients
Portal Gomes, P. W.; Mannochio-Russo, H.; Mao, J.; Zhao, H. N.; Tipton, C. D.; Ancira, J.; Dorrestein, P. C.; Li, M.
10.1101/2023.08.17.553735 — microbiology — Posted on 2023-08-18
1927 LiaX is a surrogate marker for cell-envelope stress and daptomycin non-susceptibility in Enterococcus faecium
Axell-House, D. B.; Simar, S. R.; Panesso, D.; Rincon, S.; Miller, W. R.; Khan, A.; Pemberton, O. A.; Valdez, L.; Nguyen, A. H.; Hood, K. S.; Rydell, K.; DeTranaltes, A. M.; Jones, M. N.; Atterstrom, R. L.; Reyes, J.; Sahasrabhojanec, P.; Suleyman, G.; Zervos, M. J.; Shelburne, S. A.; Singh, K. V.; Shamoo, Y.; Hanson, B. M.; Tran, T. T.; Arias, C. A.
10.1101/2023.08.18.553907 — microbiology — Posted on 2023-08-18
1928 Transcription termination factor {rho} polymerizes under stress
Wang, B.; Said, N.; Hilal, T.; Finazzo, M.; Wahl, M. C.; Artsimovitch, I.
10.1101/2023.08.18.553922 — microbiology — Posted on 2023-08-18
1932 Cell-Free Protein Expression in Polymer Materials
Lee, M. F. S.; Lee, J. A.; Biondo, J. R.; Lux, J. E.; Raig, R. M.; Berger, P. N.; Bernhards, C. B.; Kuhn, D. L.; Gupta, M. K.; Lux, M. W.
10.1101/2023.08.18.553881 — synthetic biology — Posted on 2023-08-18
1933 Endosomal activation of the Clostridioides difficile binary toxin is Ca2+-dependent
Abeyawardhane, D. L.; Adipietro, K. A.; Godoy-Ruiz, R.; Varney, K. M.; Sevdalis, S. E.; Nawaz, I. F.; Spittel, A. X.; Rustandi, R. R.; Silin, V. I.; des Georges, A.; Pozharski, E.; Weber, D. J.
10.1101/2023.08.18.553786 — biophysics — Posted on 2023-08-18
1934 Structural polymorphism of the nucleic acids in pentanucleotide repeats associated with CANVAS
Kudo, K.; Hori, K.; Asamitsu, S.; Maeda, K.; Aida, Y.; Hokimoto, M.; Matsuo, K.; Yabuki, Y.; Shioda, N.
10.1101/2023.08.17.553768 — biophysics — Posted on 2023-08-18
1937 Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer cells
Buglakova, E.; Snaebjörnsson, M.; Ekelöf, M.; Schlicker, L.; Molenaar, M. R.; Mohammed, S.; Stuart, L.; Eisenbarth, A.; Hilsenstein, V.; Schulze, A.; Alexandrov, T.
10.1101/2023.08.18.553810 — biochemistry — Posted on 2023-08-18
1939 CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan
Heilg, L.; Natasha, F.; Trinks, N.; AIMANIANDA BOPAIAH, V. K.; Sze Wah Wong, S.; Fontaine, T.; Terpitz, U.; Strobel, L.; Le Mauff, F.; Sheppard, D.; Schaeuble, S.; Kurzai, O.; Huenniger, K.; Weiss, E.; Vargas, M.; Howell, P. L.; Panagiotou, G.; Wurster, S.; Einsele, H.; Loeffler, J.
10.1101/2023.08.18.553508 — microbiology — Posted on 2023-08-18
1940 On standardization of controls in lifespan studies
Spiridonova, O.; Kriukov, D.; Nemirovich-Danchenko, N.; Peshkin, L.
10.1101/2023.08.17.552381 — systems biology — Posted on 2023-08-18
1942 Targeting CD19-positive lymphomas with the antibody-drug conjugate (ADC) loncastuximab tesirine: preclinical evidence as single agent and as combinatorial approach
Tarantelli, C.; Wald, D.; Munz, N.; Spriano, F.; Bruscaggin, A.; Cannas, E.; Cascione, L.; Gaudio, E.; Arribas, A. J.; Manjappa, S.; Golino, G.; Scalise, L.; Zucca, E.; Stathis, A.; Van Berkel, P. H.; Rossi, D.; Caimi, P. F.; Zammarchi, F.; Bertoni, F.
10.1101/2023.08.17.553668 — cancer biology — Posted on 2023-08-18
1944 Comparative transcriptome in rhesus macaques and crab-eating macaques
Mao, Y.; Li, Y.; Yang, Z.; Xu, N.; Zhang, S.; Wang, X.; Yang, X.; Sun, Q.; Mao, Y.
10.1101/2023.08.17.553631 — bioinformatics — Posted on 2023-08-18
1945 Programmable multi-kilobase RNA editing using CRISPR-mediated trans-splicing
Borrajo, J.; Javanmardi, K.; Griffin, J.; St. Martin, S. J.; Yao, D.; Hill, K.; Blainey, P.; Al-Shayeb, B.
10.1101/2023.08.18.553620 — genomics — Posted on 2023-08-18
1948 Effect of analytical variability in estimating EEG-based functional connectivity
Allouch, S.; Kabbara, A.; Duprez, J.; Paban, V.; Khalil, M.; Modolo, J.; HASSAN, M.
10.1101/2023.08.17.553675 — neuroscience — Posted on 2023-08-18
1950 A fluorescence-based sensor screen identifies MED12 as a potential microsatellite instability regulator in colon cancer
Fernandes Neto, J. M.; Venkatesan, S.; Dias, M.; Lieftink, C.; Morris, B.; Bresser, K.; Vecchione, L.; Evers, B.; Scheeren, F.; Shumacher, T.; Beijersbergen, R.; Bernards, R.
10.1101/2023.08.17.553681 — cancer biology — Posted on 2023-08-18
1952 A model of sediment retention by vegetation for Great Britain: new methodologies & validation
Hooftman, D.; Bullock, J.; Evans, P.; Redhead, J.; Ridding, L.; Varma, V.; Pywell, R.
10.1101/2023.08.17.553678 — bioinformatics — Posted on 2023-08-18
1954 Biocompatible hydrogel electrodeposition enables the simultaneous preparation of multi-microinterfaces for ligand bioconjugation and multiplexed electrochemical detection
Juska, V. B.; Moukri, N.; Estrela, P.; Maxwell, G. D.; Hendricks, S.; Santillan-Urquiza, E.; O'Brien, B.; Patella, B.; Inguanta, R.; O'riordan, A.
10.1101/2023.08.17.553669 — bioengineering — Posted on 2023-08-18
1957 Metabolism of glucose and trehalose by cyclic pentose phosphate pathway is essential for effective immune response in Drosophila
Kazek, M.; Chodakova, L.; Lehr, K.; Strych, L.; Nedbalova, P.; McMullen, E.; Bajgar, A.; Simek, P.; Moos, M.; Dolezal, T.
10.1101/2023.08.17.553657 — immunology — Posted on 2023-08-18
1958 Tertiary lymphoid structures are associated with enhanced macrophage and dendritic cell activation and proximity to CD8+ T cells, which better predict the clinical outcome of cervical cancer patients
Gorvel, L.; Panouillot, M.; Rouviere, M.-S.; Sonongbua, J.; Fattori, S.; Boucherit, N.; Ben Amara, A.; Quilichini, O.; GRANJEAUD, S.; Degos, C.; Carcopino, X.; Lambaudie, E.; Chretien, A.-S.; Sabatier, R.; Dieu-Nosjean, M.-C.; Olive, D.
10.1101/2023.08.17.552583 — immunology — Posted on 2023-08-18
1961 All-night spectral and microstate EEG analysis in patients with Recurrent Isolated Sleep Paralysis (RISP)
Cerny, F.; Piorecka, V. V.; Klikova, M. M.; Koprivova, J. J.; Buskova, J. J.; Piorecky, M. M.
10.1101/2023.08.17.551215 — neuroscience — Posted on 2023-08-18
1964 Calcium regulation of the Arabidopsis Na+/K+ transporter HKT1;1 improves seed germination under salt stress
Chandran, A. E. J.; Finkler, A.; Hait, T. A.; Kiere, Y.; David, S.; Pasmanik-Chor, M.; Shkolnik, D.
10.1101/2023.08.17.553671 — plant biology — Posted on 2023-08-18
1965 Loss of Carnitine Palmitoyltransferase 1a Reduces Docosahexaenoic Acid-Containing Phospholipids and Drives Sexually Dimorphic Liver Disease in Mice
Zelows, M. M.; Cady, C.; Dharanipragada, N.; Mead, A. E.; Kipp, Z. A.; Bates, E. A.; Venkateshwari, V.; Banerjee, R.; Park, S.-H.; Shelman, N. R.; Clarke, H. A.; Hawkinson, T. R.; Medina, T.; Sun, R. C.; Lydic, T. A.; Hinds, T. D.; Brown, J. M.; Softic, S.; Graf, G. A.; Helsley, R. N.
10.1101/2023.08.17.553705 — physiology — Posted on 2023-08-18
1966 Morphometry and mechanical instability at the onset of epithelial bladder cancer
Lampart, F. L.; Vetter, R.; Wang, Y.; Yamauchi, K. A.; Strohmeyer, N.; Meer, F.; Hussherr, M.-D.; Camenisch, G.; Rentsch, C. A.; Le Magnen, C.; Mueller, D. J.; Bubendorf, L.; Iber, D.
10.1101/2023.08.17.553533 — cancer biology — Posted on 2023-08-18
1967 The effects of skin tone on photoacoustic imaging and oximetry
Else, T. R.; Hacker, L.; Gröhl, J.; Bunce, E. V.; Tao, R.; Bohndiek, S.
10.1101/2023.08.17.553653 — bioengineering — Posted on 2023-08-18
1968 The interplay between lumen pressure and cell proliferation determines organoid morphology in a multicellular phase field model
Tanida, S.; Fuji, K.; Lu, L.; Guyomar, T.; Lee, B. H.; Honigmann, A.; Grapin-Botton, A.; Riveline, D.; Nonomura, M.; Sano, M.; Hiraiwa, T.
10.1101/2023.08.17.553655 — systems biology — Posted on 2023-08-18
1969 Deep reconstructing generative networks for visualizing dynamic biomolecules inside cells
Rangan, R.; Khavnekar, S.; Lerer, A.; Johnston, J.; Kelley, R.; Obr, M.; Kotecha, A.; Zhong, E. D.
10.1101/2023.08.18.553799 — biophysics — Posted on 2023-08-18
1973 Broadening the scope: Multiple functional connectivity networks underlying threat and safety signaling
Cushing, C. A.; Peng, Y.; Anderson, Z.; Young, K. S.; Bookheimer, S. Y.; Zinbarg, R. E.; Nusslock, R.; Craske, M. G.
10.1101/2023.08.16.553609 — neuroscience — Posted on 2023-08-18
1975 Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability
Takechi-Haraya, Y.; Ohgita, T.; Usui, A.; Nishitsuji, K.; Uchimura, K.; Abe, Y.; Kawano, R.; Konaklieva, M. I.; Reimund, M.; Remaley, A. T.; Sato, Y.; Izutsu, K.-i.; Saito, H.
10.1101/2023.08.16.553537 — biophysics — Posted on 2023-08-18
1976 Inferring the Hoxa1 Gene Regulatory Network in Mouse Embryonic Stem Cells: Time-Series RNA-seq Data and Computational Modeling Approach
Emelogu, U.; Rogers, B. T.; Banad, Y.; Cavalier, C.; Wilson, A.; Yi, X.; D'Auvergne, O.; Almeida de Oliveira, S.; Akwaboa, N.; Martinez-Ceballos, E.
10.1101/2023.08.16.553596 — bioinformatics — Posted on 2023-08-18
1977 Distinct Microstructural Heterogeneities Underpin Specific Micromechanical Properties in Human ACL Femoral and Tibial Entheses
Fang, J.; Wang, X.; Lai, H.; Li, W.; pan, z.; Mao, R.; Yan, Y.; Xie, C.; Lin, J.; Sun, W.; Li, R.; Wang, J.; Dai, J.; Xu, K.; Yu, X.; Xu, T.; Duan, W.; Qian, J.; Hongwei, O.; Dai, X.
10.1101/2023.08.16.553628 — bioengineering — Posted on 2023-08-18
1978 A Hybrid Transistor with Transcriptionally Controlled Computation and Plasticity
Gao, Y.; Zhou, Y.; Ji, X.; Graham, A. J.; Dundas, C. M.; Mahfoud, I. E. M.; Tibbett, B. M.; Tan, B.; Partipilo, G.; Dodabalapur, A.; Rivnay, J.; Keitz, B. K.
10.1101/2023.08.16.553547 — bioengineering — Posted on 2023-08-18
1979 Trans-Omics analysis of post injury thrombo-inflammation identifies endotypes and trajectories in trauma patients.
Cohen, M. J.; Erickson, C. B.; Lacroix, I. S.; Debot, M.; Dzieciatkowska, M.; Schaid, T. R.; Hallas, M. W.; Thielen, O. N.; Cralley, A. L.; Banerjee, A.; Moore, E. E.; Silliman, C. C.; D'Alessandro, A.; Hansen, K. C.
10.1101/2023.08.16.553446 — biochemistry — Posted on 2023-08-18
1980 Mapping Human Tissues with Highly Multiplexed RNA in situ Hybridization
Kalhor, K.; Chen, C.-j.; Lee, H. S.; Cai, M.; Nafisi, M.; Que, R.; Yuan, Y.; Song, J.; Lake, B.; Zhang, K.; Kharchenko, P.; Zhang, Y.; Palmer, C.; Chun, J.; Jain, S.; Knoten, A.; Gaut, J.; Keene, D.; Lein, E.; Fan, J.-B.
10.1101/2023.08.16.553610 — genomics — Posted on 2023-08-18
1984 Piezo regulates epithelial topology and promotes precision in organ size control
Kumar, N.; Mim, M. S.; Levis, M.; Unger, M.; Miranda, G.; Robinett, T.; Zartman, J. J.
10.1101/2023.08.16.553584 — developmental biology — Posted on 2023-08-18
1985 Human intestinal organoid-derived PDGFRα+ mesenchymal stroma empowers LGR4+ epithelial stem cells
JunLong, C.; Horiuchi, S.; Kuramochi, S.; Kawasaki, T.; Kawasumi, H.; Akiyama, S.; Arai, T.; Morinaga, K.; Kimura, T.; Kiyono, T.; Akutsu, H.; Ishida, S.; UMEZAWA, A.
10.1101/2023.08.16.553630 — cell biology — Posted on 2023-08-18
1986 TAX1BP1 recruits ATG9 vesicles through SCAMP3 binding
Hama, Y.; Kurikawa, Y.; Matsui, T.; Mizushima, N.; Yamamoto, H.
10.1101/2023.08.18.553817 — molecular biology — Posted on 2023-08-18
1988 Dendritic cell-mediated responses to secreted Cryptosporidium effectors are required for parasite-specific CD8+ T cell responses
Haskins, B. E.; Gullicksrud, J. A.; Wallbank, B. A.; Dumaine, J. E.; Guerin, A.; Cohn, I. S.; O'Dea, K. M.; Pardy, R. D.; Merolle, M. I.; Shallberg, L. A.; Hunter, E. N.; Byerly, J. H.; Smith, E. J.; Buenconsejo, G. Y.; McLeod, B. I.; Christian, D. A.; Striepen, B.; Hunter, C. A.
10.1101/2023.08.16.553566 — immunology — Posted on 2023-08-18
1989 A tryptophan metabolite modulates the host response to bacterial infection via kainate receptors
Parada-Kusz, M.; Clatworthy, A. E.; Goering, E. R.; Blackwood, S. M.; Salm, E. J.; Choi, C.; Combs, S.; Lee, J. S.; Rodriguez-Osorio, C.; Tomita, S.; Hung, D. T.
10.1101/2023.08.16.553532 — immunology — Posted on 2023-08-18
1998 Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response
Warfvinge, R.; Geironson Ulfsson, L.; Dhapola, P.; Safi, F.; Sommarin, M. N. E.; Soneji, S.; Hjorth-Hansen, H.; Mustjoki, S.; Richter, J.; Krishna Thakur, R.; Karlsson, G.
10.1101/2023.08.16.553504 — cancer biology — Posted on 2023-08-18
2001 Automated, high-throughput quantification of EGFP-expressing neutrophils in zebrafish by machine learning and a highly-parallelized microscope
Efromson, J.; Ferrero, G.; Begue, A.; Doman, T. J. J.; Dugo, C.; Barker, A.; Saliu, V.; Reamey, P.; Kim, K.; Harfouche, M.; Yoder, J. A.
10.1101/2023.08.16.553550 — bioinformatics — Posted on 2023-08-18
2005 Identification and functional analysis of extrachromosomal circular DNA in plasma extracellular vesicles of liver failure patients
Xiang, X.; Hong, X.; Yu, Y.; Li, J.; Yu, J.; Xiao, W.; Chen, C.; Huang, D.; Zhong, T.; Li, J.; Qian, Y.; Li, Z.
10.1101/2023.08.16.553522 — genomics — Posted on 2023-08-18
2010 Replication and Refinement of Brain Age Model for adolescent development.
Ray, B.; Chen, J.; Fu, Z.; Suresh, P.; Thapaliya, B.; Farahdel, B.; Calhoun, V. D.; Liu, J.
10.1101/2023.08.16.553472 — neuroscience — Posted on 2023-08-18
2011 A reproducible and generalizable software workflow for analysis of large-scale neuroimaging data collections using BIDS Apps
Zhao, C.; Jarecka, D.; Covitz, S.; Chen, Y.; Eickhoff, S. B.; Fair, D. A.; Franco, A. R.; Halchenko, Y. O.; Hendrickson, T. J.; Hoffstaedter, F.; Houghton, A.; Kiar, G.; Macdonald, A.; Mehta, K.; Milham, M. P.; Salo, T.; Hanke, M.; Ghosh, S. S.; Cieslak, M.; Satterthwaite, T. D.
10.1101/2023.08.16.552472 — neuroscience — Posted on 2023-08-18
2012 Colibactin-induced genotoxicity and colorectal cancer exacerbation critically depends on adhesin-mediated epithelial binding
Jans, M.; Kolata, M.; Blancke, G.; Ciers, M.; Dohlman, A. B.; Kusakabe, T.; Sze, M.; Thiran, A.; Berx, G.; Tejpar, S.; van Loo, G.; Iliev, I. D.; Remaut, H.; Vereecke, L.
10.1101/2023.08.16.553526 — cancer biology — Posted on 2023-08-18
2018 Pure wild forest reindeer (Rangifer tarandus fennicus) or hybrids? A whole-genome sequencing approach to solve the taxonomical status
Weldenegodguad, M.; Niemi, M.; Mykra-Pohja, S.; Pokharel, K.; Hamama, T.-M.; Paasivaara, A.; Kantanen, J.
10.1101/2023.08.16.553517 — genomics — Posted on 2023-08-18
2020 Inferring genetic structure of European beech from observations of spectral phenotypes
Czyz, E. A.; Schmid, B.; Eppinga, M. B.; de La Harpe, M.; Moradi, A.; Li, C.; Schaepman, M. E.; Schuman, M. C.
10.1101/2023.08.16.553487 — plant biology — Posted on 2023-08-18
2022 The genome regulatory landscape of Atlantic salmon liver through smoltification
Harvey, T.; Gillard, G. B.; Rosaeg, L. L.; Grammes, F.; Monsen, O.; Vik, J. O.; Hvidsten, T. R.; Sandve, S. R.
10.1101/2023.08.16.553484 — genomics — Posted on 2023-08-18
2023 Long-insert sequence capture detects high copy numbers in a defence-related beta-glucosidase gene Betaglu-1 with large variations in white spruce but not Norway spruce
Hung, T. H.; Wu, E. T. Y.; Zeltins, P.; Jansons, A.; Ullah, A.; Erbilgin, N.; Bohlmann, J.; Bousquet, J.; Birol, I.; Clegg, S.; MacKay, J.
10.1101/2023.08.18.551884 — evolutionary biology — Posted on 2023-08-18
2028 An effector deletion leads to the breakdown of partial grapevine resistance to downy mildew
Paineau, M.; Minio, A.; Mestre, P.; Fabre, F.; Mazet, I. D.; Couture, C.; Legeai, F.; Dumartinet, T.; Cantu, D.; Delmotte, F.
10.1101/2023.08.17.553663 — evolutionary biology — Posted on 2023-08-18
2031 A universal preservation protocol for multi-omic and histological analysis of kidney tissue
Gies, S. E.; Hänzelmann, S.; Kylies, D.; Lagies, S.; Lasse, M.; Hausmann, F.; Khatri, R.; Poets, M.; Zhang, T.; Lu, S.; Liu, S.; Chilla, S.; Edenhofer, I.; Czogalla, J.; Braun, F.; Kammerer, B.; Rinschen, M. M.; Puelles, V. G.; Bonn, S.; Lindenmeyer, M.; Huber, T. B.
10.1101/2023.08.16.553482 — genomics — Posted on 2023-08-17
2033 Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and psychiatric disease
Herborg, F. H.; Konrad, L. K.; Pugh, C. F.; Delignat-Lavaud, B.; Ratner, C.; Awadallah, N.; Pino, J. A.; Berlin, F.; Rickhag, M.; Holst, B.; Woldbye, D.; Torres, G.; Trudeau, L.-E.; Gether, U.
10.1101/2023.08.17.553695 — neuroscience — Posted on 2023-08-17
2036 Direct RNA-binding by MYCN mediates feedback from RNA processing to transcription control
Papadopoulos, D.; Ha, S. A.; Fleischhauer, D.; Uhl, L.; Schneider, K.; Mikicic, I.; Russell, T. J.; Brem, A.; Valanju, O. R.; Gallant, P.; Schuelein-Voelk, C.; Maric, H. M.; Beli, P.; Buechel, G.; Vos, S. M.; Eilers, M.
10.1101/2023.08.16.553474 — cancer biology — Posted on 2023-08-17
2037 Water migration through enzyme tunnels is sensitive to choice of explicit water model
Thirunavukarasu, A. S.; Szleper, K.; Tanriver, G.; Mitusinska, K.; Gora, A.; Brezovsky, J.
10.1101/2023.08.14.553223 — bioinformatics — Posted on 2023-08-17
2041 Complete genome-centric analysis reveals functional divergence and adaptive evolution of uncultured bacteria in anammox community
Wang, Y.-C.; Mao, Y.; Fu, H.-M.; Wang, J.; Weng, X.; Liu, Z.-H.; Xu, X.-W.; Yan, P.; Fang, F.; Guo, J.-S.; Shen, Y.; Chen, Y.-P.
10.1101/2023.08.15.553441 — microbiology — Posted on 2023-08-17
2043 Molecular dynamics analyses of CLDN15 pore size and charge selectivity
McGuinness, S.; Li, P.; Li, Y.; Fuladi, S.; Konar, S.; Bafghi, S. S.; Sidahmed, M.; Li, Y.; Shen, L.; Khalili-Araghi, F.; Weber, C. R.
10.1101/2023.08.16.553400 — physiology — Posted on 2023-08-17
2046 Altering the substitution and crosslinking of glucuronoarabinoxylans affects cell wall porosity and assembly in Brachypodium distachyon.
Tryfona, T.; Pankratova, Y.; Patrik, D.; Rebaque Moran, D.; Wightman, R.; Echevarria Poza, A.; Yu, X.; Deralia, P. K.; Vilaplana, F.; Anderson, C. T.; Hong, M.; Dupree, P.
10.1101/2023.08.17.553603 — biochemistry — Posted on 2023-08-17
2047 Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar
Esser, T. K.; Boehning, J.; Onur, A.; Chinthapalli, D. K.; Eriksson, L.; Grabarics, M.; Fremdling, P.; Konijnenberg, A.; Makarov, A. A.; Botman, A.; Peter, C.; Benesch, J. L. P.; Robinson, C. V.; Gault, J.; Baker, L.; Bharat, T. A. M.; Rauschenbach, S.
10.1101/2023.08.17.553673 — biochemistry — Posted on 2023-08-17
2050 Triaging of -helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
Muthukumar, G.; Stevens, T. A.; Inglis, A. J.; Esantsi, T. K.; Saunders, R. A.; Schulte, F.; Voorhees, R. M.; Guna, A.; Weissman, J. S.
10.1101/2023.08.16.553624 — cell biology — Posted on 2023-08-17
2051 Herpes zoster mRNA vaccine induces superior vaccine immunity over licensed vaccine in mice and rhesus macaques
Huang, L.; Zhao, T.; Zhao, W.; Zhao, H.; Zhang, L.; Gong, Y.; Zeng, X.; Weng, C.; Di, Z.; Sun, S.; Ma, W.; Wang, L.; Liu, Z.; Shi, L.; Hu, J.; Fang, S.; Zhang, C.; Zhang, J.; Wang, G.; Lore, K.; Yang, Y.; Lin, A.
10.1101/2023.08.16.553640 — immunology — Posted on 2023-08-17
2053 Decoding reveals the neural representation of held and manipulated musical thoughts
Quiroga-Martinez, D. R.; Fernandez-Rubio, G.; Bonetti, L.; Achyutuni, K. G.; Tzovara, A.; Knight, R. T.; Vuust, P.
10.1101/2023.08.15.553456 — neuroscience — Posted on 2023-08-17
2055 Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors
Silhan, J.; Fajtova, P.; Bartosova, J.; Hurysz, B.; Almaliti, J.; Miyamoto, Y.; Eckmann, L.; Gerwick, W.; O Donoghue, A.; Boura, E.
10.1101/2023.08.17.553660 — biophysics — Posted on 2023-08-17
2059 The Genetic Landscape of a Metabolic Interaction
Nguyen, T. N.; Ingle, C.; Thompson, S.; Reynolds, K. A.
10.1101/2023.05.28.542639 — biochemistry — Posted on 2023-08-17
2060 Thermodynamic Coupling of the tandem RRM domains of hnRNP A1 underlie its Pleiotropic RNA Binding Functions
Levengood, J. D.; Potoyan, D.; Penumutchu, S.; Kumar, A.; Wang, Y.; Hansen, A. L.; Kutluay, S.; Roche, J.; Tolbert, B. S.
10.1101/2023.08.17.553700 — biochemistry — Posted on 2023-08-17
2061 Nucleoporin Elys attaches peripheral chromatin to the nuclear pores in interphase nuclei
Doronin, S. A.; Ilyin, A. A.; Kononkova, A. D.; Solovyov, M. A.; Olenkina, O. M.; Nenasheva, V. V.; Mikhaleva, E. A.; Lavrov, S. A.; Ivannikova, A. Y.; Fedotova, A. A.; Khrameeva, E. E.; Ulianov, S. V.; Razin, S. V.; Shevelyov, Y. Y.
10.1101/2023.08.16.553518 — genomics — Posted on 2023-08-17
2062 Multi-omics analysis reveals critical cis-regulatory roles of transposable elements in livestock genomes
Wang, C.; Lei, B.; Bao, Y.; Wang, Z.; Chen, C.; Zhang, Y.; Qin, S.; Sun, T.; Tang, Z.; Liu, Y.
10.1101/2023.08.17.553652 — genomics — Posted on 2023-08-17
2063 A new method for multi-ancestry polygenic prediction improves performance across diverse populations
Zhang, H.; Zhan, J.; Jin, J.; Zhang, J.; Lu, W.; Zhao, R.; Ahearn, T. U.; Yu, Z.; O'Connell, J.; Jiang, Y.; Chen, T.; Okuhara, D.; 23andMe Research Team, ; Garcia-Closas, M.; Lin, X.; Koelsch, B. L.; Chatterjee, N.
10.1101/2022.03.24.485519 — genetics — Posted on 2023-08-17
2064 CRIMP: A CRISPR/Cas9 Insertional Mutagenesis Protocol and the CRIMP Toolkit
Miles, L. B.; Calcinotto, V.; Sonntag, C.; Lee, C.; Bryson-Richardson, R. J.
10.1101/2023.07.13.548929 — genetics — Posted on 2023-08-17
2068 Evolution of E. coli in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevance
Unni, R.; Andreani, N. A.; Vallier, M.; Heinzmann, S.; Taubenheim, J.; Guggeis, M. A.; Tran, F.; Vogler, O.; Hövener, J.-B.; Rosenstiel, P.; Kaleta, C.; Dempfle, A.; Unterweger, D.; Baines, J. F.
10.1101/2023.08.16.553450 — evolutionary biology — Posted on 2023-08-17
2069 Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems
Rydhmer, K.; Eckberg, J. O.; Lundgren, J. G.; Jansson, S.; Still, L.; Quinn, J. E.; Washington, R.; Lemmich, J.; Nikolajsen, T.; Sheller, N.; Michels, A. M.; Bredeson, M. M.; Rosenzweig, S. T.; Bick, E. N.
10.1101/2023.08.15.553397 — ecology — Posted on 2023-08-17
2070 BMP7 promotes cardiomyocyte regeneration
Bongiovanni, C.; Bueno-Levy, H.; Posadas Pena, S. D.; Del Bono, I.; Redaelli, S.; Bergen, M.; Da Pra, S.; Sacchi, F.; Miano, C.; Boriati, S.; Pontis, F.; Romaniello, D.; Mazzeschi, M.; Petraroia, I.; Tassinari, R.; Kellerer, L.; Lauriola, M.; Ventura, C.; Heermann, S.; Weidinger, G.; Tzahor, E.; D'Uva, G.
10.1101/2023.08.17.553475 — molecular biology — Posted on 2023-08-17
2071 Live-cell Fluorescence Microscopy of HSV-1 Cellular Egress by Exocytosis
Bergeman, M. H.; Hernandez, M. Q.; Diefenderfer, J.; Drewes, J. A.; Velarde, K.; Tierney, W. M.; Enow, J. A.; Glenn, H. L.; Rahman, M. M.; Hogue, I. B.
10.1101/2023.02.27.530373 — microbiology — Posted on 2023-08-17
2072 Prevotella copri-linked effects of a therapeutic food for malnutrition
Wang, Y.; Chang, H.-W.; Lee, E. M.; Zhou, C.; Pruss, K. M.; Henrissat, S.; Chen, R. Y.; Kao, C.; Hibberd, M. C.; Lynn, H. M.; Webber, D. M.; Crane, M.; Cheng, J.; Rodionov, D. A.; Arzamasov, A. A.; Castillo, J. J.; Couture, G.; Chen, Y.; Balcazo, N. P.; Lebrilla, C. B.; Terrapon, N.; Henrissat, B.; Ilkayeva, O.; Muehlbauer, M. J.; Newgard, C.; Mostafa, I.; Das, S.; Mahfuz, M.; Osterman, A.; Barratt, M. J.; Ahmed, T.; Gordon, J.
10.1101/2023.08.11.553030 — microbiology — Posted on 2023-08-17
2074 Iron regulatory proteins 1 and 2 have opposing roles in regulating inflammation in bacterial orchitis
Ghatpande, N.; Harrer, A.; Azoulay, B.; Guttmann-Raviv, N.; Bhushan, S.; Meinhardt, A.; Meyron-Holtz, E. G.
10.1101/2023.08.16.553579 — immunology — Posted on 2023-08-17
2078 A neurogenetic toolkit to decode Anopheles gambiae olfaction
Giraldo, D.; Hammond, A. M.; Wu, J.; Feole, B.; Al-Saloum, N.; McMeniman, C. J.
10.1101/2023.08.16.553590 — neuroscience — Posted on 2023-08-17
2080 Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata
Meccariello, A.; Hou, S.; Davydova, S.; Fawcett, J.; Siddall, A.; Leftwich, P. T.; Krsticevic, F.; Papathanos, P. A.; Windbichler, N.
10.1101/2023.08.16.553191 — synthetic biology — Posted on 2023-08-17
2086 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting
Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.
10.1101/2022.06.23.497372 — bioengineering — Posted on 2023-08-17
2087 The Metabolic Usage and Glycan Destinations of GlcNAz in E. coli
Eddenden, A.; Dooda, M. K.; Morrison, Z. A.; Subramanian, A. S.; Howell, P. L.; Troutman, J. M.; Nitz, M.
10.1101/2023.08.17.553294 — biochemistry — Posted on 2023-08-17
2088 Structural Basis for Hyperpolarization-dependent Opening of the Human HCN1 Channel
Burtscher, V.; Mount, J.; Cowgill, J.; Chang, Y.; Bickel, K.; Yuan, P.; Chanda, B.
10.1101/2023.08.17.553623 — biochemistry — Posted on 2023-08-17
2089 ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages
Bates, T. A.; Trank-Greene, M.; Nguyenla, X.; Anastas, A.; Merutka, I. R.; Dixon, S. D.; Shumate, A.; Groncki, A. R.; Parson, M. A.; Barklis, E.; Burke, J. E.; Shinde, U.; Ploegh, H. L.; Tafesse, F. G.
10.1101/2023.08.16.553641 — biochemistry — Posted on 2023-08-17
2090 Novel sterol binding domains in bacteria
Zhai, L.; Bonds, A.; Smith, C. A.; Oo, H.; Chou, J. C.-C.; Welander, P. V.; Dassama, L. M. K.
10.1101/2022.05.15.491920 — biochemistry — Posted on 2023-08-17
2092 Climate change should drive mammal defaunation in tropical dry forests
Moura, M. R.; Silva, G. A. O.; Paglia, A.; Pires, M. M.; Santos, B. A.
10.1101/2023.08.17.553094 — ecology — Posted on 2023-08-17
2094 Generation of OP7 chimera defective interfering particle preparations free of infectious influenza A virus that shows antiviral efficacy in mice
Dogra, T.; Pelz, L.; Boehme, J. D.; Kuchler, J.; Kershaw, O.; Marichal-Gallardo, P.; Baelkner, M.; Hein, M. D.; Gruber, A. D.; Benndorf, D.; Genzel, Y.; Bruder, D.; Kupke, S. Y.; Reichl, U.
10.1101/2023.08.16.553516 — molecular biology — Posted on 2023-08-17
2097 Development of an optimized, non-stem cell line for intranasal delivery of therapeutic cargo to the central nervous system
El-Ayoubi, A.; Arakelyan, A.; Klawitter, M.; Merk, L.; Hakobyan, S.; Gonzalez-Menendez, I.; Quintanilla-Fend, L.; Holm, P. S.; Mikulits, W.; Schwab, M.; Danielyan, L.; Naumann, U.
10.1101/2023.08.16.553513 — molecular biology — Posted on 2023-08-17
2098 Virological characteristics of the SARS-CoV-2 XBB.1.5 variant
Tamura, T.; Irie, T.; Deguchi, S.; Yajima, H.; Tsuda, M.; Nasser, H.; Mizuma, K.; Plianchaisuk, A.; Suzuki, S.; Uriu, K.; Begum, M. M.; Shimizu, R.; Jonathan, M.; Suzuki, R.; Kondo, T.; Ito, H.; Kamiyama, A.; Yoshimatsu, K.; Shofa, M.; Hashimoto, R.; Anraku, Y.; Kimura, K. T.; Kita, S.; Sasaki, J.; Sasaki-Tabata, K.; Maenaka, K.; Nao, N.; Wang, L.; Oda, Y.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ikeda, T.; Saito, A.; Matsuno, K.; Ito, J.; Tanaka, S.; Sato, K.; Hashiguchi, T.; Takayama, K.; Fukuhara, T.
10.1101/2023.08.16.553332 — microbiology — Posted on 2023-08-17
2099 Assembly of SARS-CoV-2 ribonucleosomes by truncated N* variant of the nucleocapsid protein
Adly, A.; Bi, M.; Carlson, C.; Syed, A. M.; Ciling, A.; Doudna, J.; Cheng, Y.; Morgan, D. O.
10.1101/2023.08.16.553581 — microbiology — Posted on 2023-08-17
2104 Intracellular Pseudomonas aeruginosa within the airway epithelium of Cystic Fibrosis lung tissues
Malet, J. K.; Faure, E.; Adam, D.; Donner, J.; Liu, L.; Pilon, S.-J.; Fraser, R.; Jorth, P.; Newman, D. K.; Brochiero, E.; Rousseau, S.; Nguyen, D.
10.1101/2023.08.17.552973 — microbiology — Posted on 2023-08-17
2105 Determinants of Gastrointestinal Group B Streptococcus Carriage in Adults
Cowley, E. S.; Chaves, I. Z.; Osman, F.; Suen, G.; Anantharaman, K.; Hryckowian, A.
10.1101/2023.08.17.553755 — microbiology — Posted on 2023-08-17
2106 Granulomatous inflammatory responses are elicited in the liver of PD-1 knockout mice by de novo genome mutagenesis
Nagaretnam, I.; Yoneshige, A.; Takeuchi, F.; Ozaki, A.; Tamura, M.; Suzuki, S.; Shigeoka, T.; Ito, A.; Ishida, Y.
10.1101/2023.08.17.553694 — immunology — Posted on 2023-08-17
2109 Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections
Schupp, P. G.; Shelton, S. J.; Brody, D. J.; Eliscu, R.; Johnson, B. E.; Mazor, T.; Kelley, K. W.; Potts, M. B.; McDermott, M. W.; Huang, E. J.; Lim, D. A.; Pieper, R. O.; Berger, M. S.; Costello, J. F.; Phillips, J. J.; Oldham, M. C.
10.1101/2023.06.21.545365 — cancer biology — Posted on 2023-08-17
2111 In silico mechanics and TGF-β expression of stem cells intramyocardially transplanted with a biomaterial injectate for treatment of myocardial infarction
Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Nchejane, N. J.; Abdalrahman, T.; Nagawa, J.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.
10.1101/2023.05.10.540185 — bioengineering — Posted on 2023-08-17
2112 Signaling mechanisms and agricultural applications of (Z)-3-Hexenyl Butyrate-mediated stomatal closure
Paya, C.; Belda-Palazon, B.; Vera-Sirera, F.; Perez-Perez, J.; Jorda, L.; Rodrigo, I.; Belles, J.; Lopez-Gresa, M. P.; Lison, P.
10.1101/2023.05.26.542418 — molecular biology — Posted on 2023-08-17
2113 Adaptor protein complex 2 in the orbitofrontal cortexpredicts alcohol use disorder
Mulholland, P. J.; Berto, S.; Wilmarth, P.; McMahan, C.; Ball, L.; Woodward, J.
10.1101/2023.05.28.542637 — neuroscience — Posted on 2023-08-17
2114 ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice
Schuster, K. H.; Zalon, A. J.; DiFranco, D. M.; Putka, A. F.; Stec, N.; Jarrah, S.; Naeem, A.; Haque, Z.; Zhang, H.; Guan, Y.; McLoughlin, H. S.
10.1101/2022.07.18.500473 — neuroscience — Posted on 2023-08-17
2117 A novel patient-derived cellular platform for validating microglia-targeted therapeutics for Alzheimer's disease
Cuni-Lopez, C.; Stewart, R.; Okano, S.; Redlich, G. L.; Appleby, M. W.; White, A. R.; Quek, H.
10.1101/2023.08.17.552618 — cell biology — Posted on 2023-08-17
2118 Neural network emulation of the human ventricular cardiomyocyte action potential: a tool for more efficient computation in pharmacological studies
Grandits, T.; Augustin, C. M.; Haase, G.; Jost, N.; Mirams, G. R.; Niederer, S. A.; Plank, G.; Varro, A.; Virag, L.; Jung, A.
10.1101/2023.08.16.553497 — cell biology — Posted on 2023-08-17
2120 Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
Ayoubi, R.; Ryan, J.; Biddle, M. S.; Alshafie, W.; Fotouhi, M.; Bolivar, S. G.; Moleon, V. R.; Eckmann, P.; Worrall, D.; McDowell, I.; Southern, K.; Reintsch, W.; Durcan, T. M.; Brown, C. M.; Bandrowski, A. E.; Virk, H. S.; Edwards, A. M.; McPherson, P. S.; Laflamme, C.
10.1101/2023.06.01.543292 — molecular biology — Posted on 2023-08-17
2125 Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains
Mancinelli, C.; Marx, D. C.; Gonzalez-Hernandez, A. J.; Mancinelli, L.; Khelashvili, G.; Levitz, J.; Eliezer, D.
10.1101/2023.08.16.553551 — biophysics — Posted on 2023-08-17
2127 DONSON is required for CMG helicase assembly in the mammalian cell cycle
Labib, K.; Evrin, C.; Alvarez, V.; Ainsworth, J.; Fujisawa, R.; Alabert, C.
10.1101/2023.08.16.553614 — biochemistry — Posted on 2023-08-17
2129 Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein
Mooren, O. L.; Stuchell-Brereton, M. D.; McConnell, P.; Yan, C.; Wilkerson, E. M.; Goldfarb, D.; Cooper, J. A.; Sept, D.; Soranno, A.
10.1101/2023.08.16.553570 — biochemistry — Posted on 2023-08-17
2130 Optimal transport for mapping senescent cells in spatial transcriptomics
Nguyen, N. D.; Rosas, L.; Khaliullin, T.; Jiang, P.; Hasanaj, E.; Ovando, J. A.; Bueno, M.; Konigshoff, M.; Eickelberg, O.; Rojas, M.; Mora, A. L.; Lugo-Martinez, J.; Bar-Joseph, Z.
10.1101/2023.08.16.553591 — cell biology — Posted on 2023-08-17
2131 Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation
Urbauer, E.; Aguanno, D.; Mindermann, N.; Omer, H.; Metwaly, A.; Khaloian, S.; Reitmeier, S.; Remke, M.; Jarosch, S.; Huber, S.; Busch, D. H.; Stecher, B.; Allez, M.; Steiger, K.; Rath, E.; Haller, D.
10.1101/2023.07.27.549844 — microbiology — Posted on 2023-08-17
2133 Acetylcholine Modulates the Precision of Prediction Error in the Auditory Cortex
Perez-Gonzalez, D.; Lao Rodriguez, A. B.; Aedo-Sanchez, C.; Malmierca, M. S.
10.1101/2023.08.17.553683 — neuroscience — Posted on 2023-08-17
2135 Deciphering Salt Stress Responses in Solanum pimpinellifolium through High-Throughput Phenotyping.
Morton, M. M.; Fiene, G.; Ahmed, H. I.; Rey, E.; Abrouk, M.; Angel, Y.; Johansen, K.; Saber, N. O.; Malbeteau, Y.; Al-Mashharawi, S.; Ziliani, M. G.; Aragon, B.; Oakey, H.; Berger, B.; Brien, C.; Krattinger, S.; Mousa, M.; McCabe, M. F.; Negrao, S.; Tester, M. A.; Julkowska, M. M.
10.1101/2023.08.15.553433 — plant biology — Posted on 2023-08-17
2136 Oxytocin alleviated colitis and colitis-associated colorectal tumorigenesis by targeting fucosylated MUC2
Wang, X.; Chen, D.; Guo, M.; Ning, Y.; Guo, J.; Gao, J.; Xie, X.; Zhao, D.; Li, L.; Li, S.; Li, Y.; Zuo, X.; Li, J.
10.1101/2023.08.17.553684 — physiology — Posted on 2023-08-17
2137 Novel Insights into the Aortic Mechanical Properties of Mice Modeling Hereditary Aortic Diseases
Dubacher, N.; Sugiyama, K.; Smith, J. D.; Nussbaumer, V.; Csonka, M.; Ferenczi, S.; Kovacs, K. J.; Caspar, S. M.; Lamberti, L.; Meienberg, J.; Yanagisawa, H.; Sheppard, M. B.; Matyas, G.
10.1101/2023.08.15.553452 — pathology — Posted on 2023-08-17
2138 Combined PI3K and MAPK inhibition synergizes to suppress PDAC
Bye, B.; Jack, J.; Pierce, A.; Walsh, R. M.; Eades, A.; Olou, A.; Chalise, P.; VanSaun, M.
10.1101/2023.08.15.553438 — cancer biology — Posted on 2023-08-17
2144 DifferentialRegulation: a Bayesian hierarchical approach to identify differentially regulated genes
Tiberi, S.; Meili, J.; Cai, P.; Soneson, C.; He, D.; Sarkar, H.; Avalos-Pacheco, A.; Patro, R.; Robinson, M. D.
10.1101/2023.08.17.553679 — bioinformatics — Posted on 2023-08-17
2145 Non-invasive Imaging Techniques for Monitoring Cellular Response to Treatment in Stable Vitiligo
Shiu, J.; Lentsch, G.; Polleys, C. M.; Mobasher, P.; Ericson, M.; Georgakoudi, I.; Ganesan, A. K.; Balu, M.
10.1101/2023.08.15.553419 — bioengineering — Posted on 2023-08-17
2146 Impact of Yaq-001, a non-absorbable, engineered carbon bead of controlled porosity in rodent models of cirrhosis and acute on chronic liver failure
Liu, J.; Macnaughtan, J.; Jin, Y.; Clasen, F.; Habtesion, A.; Phillips, A.; De Chiara, F.; Ingavle, G.; Cordero-Sanchez, P.; Soeda, J.; Oben, J. A.; Li, J.; Wu, H.; Ann Edwards, L.; Cox, I. J.; Sandeman, S.; Davies, N.; Mookerjee, R.; Mehta, G.; Shoaie, S.; Marchesi, J. R.; Andreola, F.; Jalan, R.
10.1101/2023.08.15.553396 — animal behavior and cognition — Posted on 2023-08-17
2151 Splenocytes and thymocytes migration patterns between lymphoid organs in pregnancy
Cruz-Cureno, G. T.; Rosales-Tarteaut, M. C.; Arriaga-Pizano, L. A.; Sanchez-Torres, L. E.; Castro-Eguiluz, D.; Prieto-Chavez, J. L.; Pastelin-Palacios, R.; Flisser, A.; Cerbulo-Vazquez, A.
10.1101/2023.08.15.553414 — immunology — Posted on 2023-08-17
2154 Exploring Temporal and Sex-Linked Dysregulation in Alzheimer's Disease Phospho-Proteome
Yilmaz, S.; Lopes, F. B. T. P.; Schlatzer, D.; Wang, R.; Qi, X.; Koyuturk, M.; Chance, M.
10.1101/2023.08.15.553056 — neuroscience — Posted on 2023-08-17
2156 Engineered 3D Immuno-Glial-Neurovascular Human Brain Model
Stanton, A. E.; Bubnys, A.; Agbas, E.; James, B.; Park, D. S.; Jiang, A.; Pinals, R. L.; Truong, N.; Loon, A.; Staab, C.; Liu, L.; Cerit, O.; Wen, H.-L.; Kellis, M.; Blanchard, J. W.; Langer, R. S.; Tsai, L.-H.
10.1101/2023.08.15.553453 — neuroscience — Posted on 2023-08-17
2164 Physics-informed deep generative learning for quantitative assessment of the retina
Brown, E.; Guy, A.; Holroyd, N.; Sweeney, P.; Gourmet, L.; Coleman, H.; Walsh, C.; Markaki, A.; Shipley, R.; Rajendram, R.; Walker-Samuel, S.
10.1101/2023.07.10.548427 — biophysics — Posted on 2023-08-17
2166 Identifying signals of memory from observations of animal movements in Plato's cave
Kim, D.; Thompson, P.; Wolfson, D.; Merkle, J.; Oliveira-Santos, L. G. R.; Forester, J.; Avgar, T.; Lewis, M.; Fieberg, J.
10.1101/2023.08.15.553411 — ecology — Posted on 2023-08-17
2168 Spatio-temporal dynamics of microglia phenotype in human and murine cSVD: impact of acute and chronic hypertensive states
Morton, L.; Arndt, P.; Garza, A. P.; Henneicke, S.; Mattern, H.; Gonzalez, M.; Dityatev, A.; Yilmazer-Hanke, D.; Schreiber, S.; Dunay, I. R.
10.1101/2023.08.15.553403 — neuroscience — Posted on 2023-08-17
2169 Neural geometrodynamics: a psychedelic perspective
Ruffini, G.; Lopez-Sola, E.; Vohryzek, J.; Sanchez-Todo, R.
10.1101/2023.08.14.553258 — neuroscience — Posted on 2023-08-17
2174 Increasing the accuracy of single-molecule data analysis using tMAVEN
Verma, A. R.; Ray, K. K.; Bodick, M. E.; Kinz-Thompson, C. D.; Gonzalez, R. L.
10.1101/2023.08.15.553409 — biophysics — Posted on 2023-08-17
2178 Conserved and tissue-specific immune responses to biologic scaffold implantation
DeStefano, S.; Josyula, A.; Faust, M.; Fertil, D.; Lokwani, R.; Ngo, T. B.; Sadtler, K.
10.1101/2023.08.15.553390 — bioengineering — Posted on 2023-08-17
2180 Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems
Rydhmer, K.; Eckberg, J. O.; Lundgren, J. G.; Jansson, S.; Still, L.; Quinn, J. E.; Washington, R.; Lemmich, J.; Nikolajsen, T.; Sheller, N.; Michels, A. M.; Bredeson, M. M.; Bick, E. N.; Rosenzweig, S. T.
10.1101/2023.08.15.553397 — ecology — Posted on 2023-08-17
2184 Distinct clades of TELOMERE REPEAT BINDING transcriptional regulators interplay to regulate plant development
Amiard, S.; Feit, L.; Simon, L.; Le Goff, S.; loizeau, l.; Wolff, L.; Butter, F.; Bourbousse, C.; Barneche, F.; Tatout, C.; Probst, A.
10.1101/2023.08.16.553498 — plant biology — Posted on 2023-08-17
2185 A versatile framework for drug-target interaction prediction by considering domain specific features
Liu, S.; Yu, J.; Ni, N.; Wang, Z.; Chen, M.; Li, Y.; Xu, C.; Ding, Y.; Zhang, J.; Yao, X.; Liu, H.
10.1101/2023.08.01.551396 — bioinformatics — Posted on 2023-08-17
2186 Highly multiplexed mRNA quantitation with CRISPR-Cas13
Kang, B.; Zhang, J.; Schwoerer, M. P.; Nelson, A. N.; Schoeman, E.; Ploss, A.; Myhrvold, C.
10.1101/2023.08.16.553527 — molecular biology — Posted on 2023-08-17
2188 CRISPR/Cas9 screen identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer
Boumelha, J.; de Castro, A.; Bah, N.; Cha, H.; de Carne Trecesson, S.; Rana, S.; Anastasiou, P.; Mugarza, E.; Moore, C.; Goldstone, R.; East, P.; Litchfield, K.; Lee, S.-H.; Molina-Arcas, M.; Downward, J.
10.1101/2023.04.13.536740 — cancer biology — Posted on 2023-08-17
2190 Imaging Microglia Surveillance during Sleep-wake Cycles in Freely Behaving Mice
Gu, X.; Zhao, Z.; Chen, X.; Zhang, L.; Fang, H.; Zhao, T.; Ju, S.; Gao, W.; Qian, X.; Wang, X.; Zhang, J.; Cheng, H.
10.1101/2023.02.03.527083 — neuroscience — Posted on 2023-08-17
2193 Dopamine Release Plateau and Outcome Signals in Dorsal Striatum Contrast with Classic Reinforcement Learning Formulations
Kim, M. J.; Gibson, D. J.; Hu, D.; Mahar, A.; Schofield, C. J.; Sompolpong, P.; Yoshida, T.; Tran, K. T.; Graybiel, A. M.
10.1101/2023.08.15.553421 — neuroscience — Posted on 2023-08-17
2195 Decoding reveals the neural representation of held and manipulate musical thoughts
Quiroga-Martinez, D. R.; Fernandez-Rubio, G.; Bonetti, L.; Achyutuni, K. G.; Tzovara, A.; Knight, R. T.; Vuust, P.
10.1101/2023.08.15.553456 — neuroscience — Posted on 2023-08-17
2198 Situating the parietal memory network in the context of multiple parallel distributed networks using high-resolution functional connectivity
Kwon, Y. H.; Salvo, J. J.; Anderson, N.; Holubecki, A. M.; Lakshman, M.; Yoo, K.; Kay, K.; Gratton, C.; Braga, R. M.
10.1101/2023.08.16.553585 — neuroscience — Posted on 2023-08-17
2199 The Role of Potassium and Calcium Currents in the Bistable Firing Transition
Borges, F. d. S.; Protachevicz, P. R.; Souza, D. L. M.; Bittencourt, C. F.; Gabrick, E. C.; Bentivoglio, L. E.; Szezech, J. D.; Batista, A. M.; Caldas, I. L.; Dura-Bernal, S.; Pena, R. F.
10.1101/2023.08.16.553625 — neuroscience — Posted on 2023-08-17
2202 Activation of the TRIF pathway and downstream targets results in the development of precancerous lesions during infection with Helicobacter.
Bali, P.; Lozano-Pope, I.; Hernandez, J.; Estrada, M. V.; Corr, M.; Turner, M. A.; Bouvet, M.; Benner, C.; Obonyo, M.
10.1101/2023.06.04.543598 — cancer biology — Posted on 2023-08-16
2206 The genomics and physiology of abiotic stressors associated with global elevation gradients in Arabidopsis thaliana
Gamba, D.; Lorts, C.; Haile, A.; Sahay, S.; Lopez, L.; Xia, T.; Takou, M.; Kulesza, E.; Elango, D.; Kerby, J.; Yifru, M.; Bulafu, C. E.; Wondimu, T.; Glowacka, K.; Lasky, J.
10.1101/2022.03.22.485410 — evolutionary biology — Posted on 2023-08-16
2209 Modeling the Effects of Transcranial Magnetic Stimulation on Spatial Attention
Jing, Y.; Numssen, O.; Weise, K.; Kalloch, B.; Buchberger, L.; Haueisen, J.; Hartwigsen, G.; Knoesche, T.
10.1101/2023.01.11.523548 — neuroscience — Posted on 2023-08-16
2211 Ageing attenuates exercise-enhanced motor cortical plasticity
Curtin, D.; Cadwallader, C. J.; Taylor, E. M.; Andrews, S. C.; Stout, J. C.; Hendrikse, J. J.; Chong, T. T.-J.; Coxon, J. P.
10.1101/2023.08.14.553314 — neuroscience — Posted on 2023-08-16
2214 TCGEx: A visual interface for multifaceted analyses of The Cancer Genome Atlas gene expression data
Kus, M. E.; Sahin, C.; Kilic, E.; Askin, A.; Ozgur, M. M.; Karahanogullari, G.; Aksit, A.; O'Connell, R. M.; Ekiz, H. A.
10.1101/2023.08.14.553075 — bioinformatics — Posted on 2023-08-16
2215 A Weights-based variant ranking pipeline for familial complex disorders
Ralli, S.; Vira, T.; Robles-Espinoza, C. D.; Adams, D. J.; Brooks-Wilson, A. R.
10.1101/2023.08.14.553248 — genomics — Posted on 2023-08-16
2216 Long-term combination therapy with Metformin and Oxymetholone in a Fanconi Anemia mouse model
Grompe, M.; Dorrell, C. S.; Peters, A. M.; Zhang, Q.; Balaji, N.; Mochizuki-Kashio, M.; Major, A.; Finegold, M. J.; Liu, C.; Lu, K.
10.1101/2023.08.16.553572 — genetics — Posted on 2023-08-16
2217 Hypoxia regulate developmental coronary angiogenesis potentially through VEGFR2- and SOX17-mediated signaling
Vitali, H. E.; Kuschel, B.; Sherpa, C.; Jones, B. W.; Jacob, N. S.; Madiha, S. A.; Elliott, S.; Dziennik, E.; Kreun, L.; Conatser, C.; Bhetwal, B. P.; Sharma, B.
10.1101/2023.08.16.553531 — developmental biology — Posted on 2023-08-16
2218 CDK activity at the centrosome regulates the cell cycle
Roberts, E. L.; Kapadia, N.; Auchynnikava, T.; Basu, S.; Nurse, P.
10.1101/2023.08.16.553560 — cell biology — Posted on 2023-08-16
2219 Origin and modern microbial ecology of secondary mineral deposits in Lehman Caves, Great Basin National Park, NV, USA
Havlena, Z. E.; Hose, L. D.; DuChene, H. R.; Baker, G. M.; Powell, D.; Labrado, A. L.; Brunner, B.; Jones, D. S.
10.1101/2023.08.15.553329 — microbiology — Posted on 2023-08-16
2220 Characteristics of vaginal microbes and classification of the vaginal microbiome
Zhu, B.; Spaine, K. M.; Edupuganti, L.; Matveyev, A.; Serrano, M. G.; Buck, G. A.
10.1101/2023.08.16.553525 — microbiology — Posted on 2023-08-16
2222 Population coding of time-varying sounds in the non-lemniscal Inferior Colliculus
Shi, K.; Quass, G. L.; Rogalla, M. M.; Ford, A. N.; Czarny, J. E.; Apostolides, P. F.
10.1101/2023.08.14.553263 — neuroscience — Posted on 2023-08-16
2227 Quercetin alleviates intestinal oxidative stress in Jilin White geese
Liu, L. Y.; Guo, G. W.; Jia, J. F.; Wang, W. K.; Li, L. Z.; Zhang, Z. T.; Liu, L. M.; zhou, h.
10.1101/2023.08.14.553261 — zoology — Posted on 2023-08-16
2228 Estimation of in-vivo cerebrospinal fluid velocity using fMRI inflow effect
Diorio, T. C.; Vijayakrishnan Nair, V.; Hedges, L. E.; Rayz, V. L.; Tong, Y.
10.1101/2023.08.14.553250 — physiology — Posted on 2023-08-16
2229 A Novel, Uniquely Efficacious Type of CFTR Corrector with Complementary Mode of Action
Marchesin, V.; Monnier, L.; Blattmann, P.; Chevillard, F.; Kuntz, C.; Forny, C.; Kamper, J.; Studer, R.; Bossu, A.; Ertel, E.; Nayler, O.; Brotschi, C.; Williams, J. T.; Gatfield, J.
10.1101/2023.08.15.552928 — pharmacology and toxicology — Posted on 2023-08-16
2231 Osteoclast-Cancer Cell Metabolic Symbiosis Renders PARP Inhibitor Therapy Resistance in Bone Metastasis
Fan, H.; Xu, Z.; Yao, K.; Zheng, B.; Zhang, Y.; Wang, X.; Zhang, T.; Li, X.; Hu, H.; Yue, B.; Hu, Z.; Zheng, H.
10.1101/2023.08.15.553338 — cancer biology — Posted on 2023-08-16
2232 Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
Kulkarni, A.; Mohan, V.; Tang, T.; Post, L.; Manning, M.; Thio, N.; Parker, B. L.; Rosenbluh, J.; Vissers, J. H. A.; Harvey, K. F.
10.1101/2023.08.16.553491 — cancer biology — Posted on 2023-08-16
2233 The eIF4A2 negative regulator of mRNA translation promotes extracellular matrix deposition to accelerate hepatocellular carcinoma initiation
Moore, M.; Pardo, L.; Mitchell, L.; Schmidt, T.; May, S.; Mueller, M.; Strathdee, D.; Bryson, S.; Hodge, K.; Lilla, S.; Zanivan, S.; Waldron, J.; McGarry, L.; Peter-Durairaj, R.; Kanellos, G.; Nixon, C.; Ballantyne, F.; LeQuesne, J.; Sansom, O. J.; Bird, T.; Bushell, M.; Norman, J. C.
10.1101/2023.08.16.553544 — cancer biology — Posted on 2023-08-16
2234 EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes
Huang, Y.; Durall, R. T.; Luong, N. M.; Hertzler, H. J.; Huang, J.; Gokhale, P. C.; Leeper, B. A.; Persky, N. S.; Root, D. E.; Anekal, P. V.; Montero Llopis, P. D.; David, C. N.; Kutok, J. L.; Raimondi, A.; Saluja, K.; Luo, J.; Zahnow, C. A.; Adane, B.; Stegmaier, K.; Hawkins, C. E.; Ponne, C.; Le, Q.; Shapiro, G. I.; Lemieux, M. E.; Eagen, K. P.; French, C. A.
10.1101/2023.08.15.553204 — cancer biology — Posted on 2023-08-16
2235 Robust and resource-optimal dynamic pattern formation of Min proteins in vivo
ren, z.; Weyer, H.; Wurthner, L.; Li, D.; Sou, C.; Villarreal, D.; Frey, E.; Jun, S.
10.1101/2023.08.15.553443 — biophysics — Posted on 2023-08-16
2239 Bacteriophage P22 SieA mediated superinfection exclusion
Leavitt, J. C.; Woodbury, B. M.; Gilcrease, E. B.; Bridges, C. M.; Teschke, C. M.; Casjens, S. R.
10.1101/2023.08.15.553423 — biochemistry — Posted on 2023-08-16
2240 Sulfasalazine promotes myogenic differentiation via increasing of fast myosin heavy chain isoforms
Cho, S.; Choi, S.; Chang, H.; Tran, N. K.; Lee, H.; Ryu, S.; Park, M.; Choi, S.; Park, J.; Park, J.
10.1101/2023.08.15.553466 — biochemistry — Posted on 2023-08-16
2241 Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP
Nadel, C. M.; Wucherer, K.; Oehler, A.; Thwin, A. C.; Basu, K.; Callahan, M. D.; Southworth, D. R.; Mordes, D. A.; Craik, C. S.; Gestwicki, J. E.
10.1101/2023.08.16.553575 — biochemistry — Posted on 2023-08-16
2243 Detecting altered hepatic lipid oxidation by MRI in an animal model of NAFLD
McLeod, M. A.; Ragavan, M.; Chang, M.; Mahar, R.; Giacalone, A.; Rushin, A.; Glanz, M.; Malut, V.; Graham, D.; Sunny, N.; Merritt, M.
10.1101/2023.08.16.553555 — biochemistry — Posted on 2023-08-16
2244 Probing the DCAF12 interactions with MAGEA3 and CCT5 C-terminal degrons
Righetto, G. L.; Yin, Y.; Vu, V.; Duda, D.; Szewczyk, M.; Zeng, H.; Li, Y.; Loppnau, P.; Mei, T.; Li, Y.-Y.; Seitova, A.; Brazeau, J.-F.; Barsyte-Lovejoy, D.; Santhakumar, V.; Chaudhry, C.; Halabelian, L.
10.1101/2023.08.15.553295 — biochemistry — Posted on 2023-08-16
2247 Hemin decreases cellular aging and enhances healthspan and lifespan through the AMPK pathway
Zhang, Y.; Naaz, A.; Faidzinn, N. A.; Yogasundaram, S.; Cheng, T. Y. N.; Jing, J. L.; Morel Gan, I. W.-H. J.; Junqi, C.; Alfatah, M.
10.1101/2023.08.15.553367 — genetics — Posted on 2023-08-16
2248 High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus
Nigrovic, P. A.; Wang, Q.; Kim, T.; Martinez-Bonet, M.; Sim, S.; Aguiar, V.; Cui, J.; Sparks, J. A.; Chen, X.; Todd, M.; Wauford, B.; Weirauch, M. T.; Gutierrez-Arcelus, M.
10.1101/2023.08.16.553538 — genetics — Posted on 2023-08-16
2250 Individual genotype but not phenotype predicts river migration success in Atlantic salmon
Moccetti, P.; Bolland, J. D.; Adams, C. E.; Rodger, J. R.; Honkanen, H. M.; Newton, M.; Lothian, A. J.; Nunn, A. D.; Joyce, D. A.
10.1101/2023.08.15.553252 — evolutionary biology — Posted on 2023-08-16
2252 The apparent loss of PRC2 chromatin occupancy as an artefact of RNA depletion
Healy, E.; Zhang, Q.; Gail, E. H.; Agius, S. C.; Sun, G.; Bullen, M.; Pandey, V.; Das, P. P.; Polo, J. M.; Davidovich, C.
10.1101/2023.08.16.553488 — molecular biology — Posted on 2023-08-16
2253 Achatina fulica Haemocyanin-Derived Peptides as Novel Antimicrobial Agents
Pereira Patino, A. E.; Suarez Largo, L. A.; Roman, T.; Guzman Quimbayo, F.; Rincon-Orozco, B.; Sierra Guevara, L. T.; Hidalgo Bucheli, W. F.
10.1101/2023.08.15.553437 — microbiology — Posted on 2023-08-16
2254 Complete genome-centric analysis reveals functional divergence and adaptive evolution of uncultured bacteria in anammox community
Wang, Y.; Mao, Y.; Fu, H.-M.; Wang, J.; Weng, X.; Liu, Z.-H.; Xu, X.-W.; Yan, P.; Fang, F.; Guo, J.-S.; Shen, Y.; Chen, Y.-P.
10.1101/2023.08.15.553441 — microbiology — Posted on 2023-08-16
2257 TroR is the primary regulator of the iron homeostasis transcription network in the halophilic archaeon Haloferax volcanii
Martinez-Pastor, M.; Sakrikar, S.; Hwang, S.; Hackley, R. K.; Soborowski, A.; Maupin-Furlow, J. A.; Schmid, A. K.
10.1101/2023.08.16.553580 — microbiology — Posted on 2023-08-16
2258 Defense mechanism of a bacterial retron supramolecular assembly
Wang, Y.; Wang, C.; Guan, Z.; Cao, J.; Xu, J.; Wang, S.; Cui, Y.; Wang, Q.; Chen, Y.; Zhang, D.; Sun, M.; Tao, P.; Zou, T.
10.1101/2023.08.16.553469 — microbiology — Posted on 2023-08-16
2260 TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling.
Xiong, L.; Zhevlakova, I.; West, X. Z.; Gao, D.; Murtazina, R.; Horak, A.; Brown, J. M.; Molokotina, I.; Podrez, E. A.; Byzova, T. V.
10.1101/2023.08.14.553236 — immunology — Posted on 2023-08-16
2262 Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis
Gudd, C. L. C.; Atkinson, S. R.; Mitchell, E.; Mawhin, M.-A.; Turajlic, S.; Larkin, J.; Thursz, M. R.; Goldin, R. D.; Powell, N.; Antoniades, C. G.; Woollard, K. J.; Possamai, L. A.; Triantafyllou, E.
10.1101/2023.08.14.553197 — immunology — Posted on 2023-08-16
2264 Temperature sensitivity of bat antibodies links metabolic state with antigen-recognition diversity
Toshkova, N.; Zhelyzkova, V.; Reyes-Ruiz, A.; de Castro Deus, M.; Lacombe, R. V.; Lecerf, M.; Planchais, C.; Dimitrov, J. D.
10.1101/2023.08.14.553222 — immunology — Posted on 2023-08-16
2266 Sex Dependent Regional Differences in Dopamine Release Determined by Chronic Fast-Scan Cyclic Voltammetry in Nucleus Accumbens and Dorsal Striatum
Gonzalez, I. L.; Turner, C. A.; Patel, P. R.; Leonardo, N. B.; Luma, B. D.; Richie, J. M.; Cai, D.; Chestek, C. A.; Becker, J. B.
10.1101/2023.08.14.553278 — neuroscience — Posted on 2023-08-16
2267 Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target
Caldi Gomes, L.; Hänzelmann, S.; Oller, S.; Parvaz, M.; Hausmann, F.; Khatri, R.; Ebbing, M.; Holzapfel, C.; Pasetto, L.; Fabrizio Columbro, S.; Scozzari, S.; Gebelin, M.; Knöferle, J.; Cordts, I.; Demleitner, A. F.; Tzeplaeff, L.; Deschauer, M.; Dufke, C.; Sturm, M.; Zhou, Q.; Zelina, P.; Sudria-Lopez, E.; Haack, T. B.; Streb, S.; Kuzma-Kozakiewicz, M.; Edbauer, D.; Pasterkamp, R. J.; Laczko, E.; Rehrauer, H.; Schlapbach, R.; Carapito, C.; Bonetto, V.; Bonn, S.; Lingor, P.
10.1101/2023.08.14.553180 — neuroscience — Posted on 2023-08-16
2268 APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease
Jackson, R. J.; Keiser, M. S.; Meltzer, J. C.; Fykstra, D. P.; Dierksmeier, S. E.; Melloni, A.; Nakajima, T.; Tecedor, L.; Ranum, P. T.; Carrell, E.; Chen, Y.; Holtzman, D. M.; Davidson, B. L.; Hyman, B. T.
10.1101/2023.08.14.552850 — neuroscience — Posted on 2023-08-16
2269 Action monitoring boosts perceptual confidence
Sanchez, R.; Davranche, K.; Gajdos, T.; Desantis, A.
10.1101/2023.08.14.553210 — neuroscience — Posted on 2023-08-16
2271 TgF344-AD rat model of Alzheimer's disease: spatial disorientation and asymmetry in hemispheric neurodegeneration
Sagalajev, B.; Lennartz, L.; Vieth, L.; Gunawan, C. T.; Neumaier, B.; Drzezga, A.; Visser-Vandewalle, V.; Endepols, H.; Sesia, T.
10.1101/2023.08.14.553199 — neuroscience — Posted on 2023-08-16
2273 IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination
Montilla, A.; Zabala, A.; Calvo, I.; Mata, P.; Tome, I.; Koster, M.; Sierra, A.; Kooistra, S. M.; Soria, F. N.; Eggen, B. J. L.; Fresnedo, O.; Fernandez, J. A.; Tepavcevic, V.; Matute, C.; Domercq, M.
10.1101/2023.08.14.553274 — neuroscience — Posted on 2023-08-16
2274 Reduced PIN1 gene expression in neocortical and limbic brain regions in female Alzheimer's patients correlates with cognitive and neuropathological phenotypes
de Avila Dal Bo, C.; Suazo, C.; Nolz, J.; Cochran, J. N.; WANG, Q.; Velazquez, R.; Dammer, E. B.; Readhead, B.; mastroeni, d.
10.1101/2023.08.14.553279 — neuroscience — Posted on 2023-08-16
2276 Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation
Mainali, R.; Buechler, N.; Ortero, C.; Edwards, L.; Key, C.-C.; Furdui, C.; Quinn, M. A.
10.1101/2023.08.14.553243 — physiology — Posted on 2023-08-16
2278 Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography
Smith, N.; Dasgupta, M.; Wych, D. C.; Dolamore, C.; Sierra, R. G.; Lisova, S.; Marchany-Rivera, D.; Cohen, A. E.; Boutet, S.; Hunter, M. S.; Kupitz, C.; Poitevin, F.; Moss, F. R.; Brewster, A. S.; Sauter, N. K.; Young, I. D.; Wolff, A. M.; Tiwari, V. K.; Kumar, N.; Berkowitz, D. B.; Hadt, R. G.; Thompson, M. C.; Follmer, A. H.; Wall, M. E.; Wilson, M. A.
10.1101/2023.08.15.553460 — biochemistry — Posted on 2023-08-16
2279 The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis
Acevedo, A.; Jones, A. E.; Danna, B. T.; Turner, R.; Montales, K. P.; Beninca, C.; Reue, K.; Shirihai, O. S.; Stiles, L.; Wallace, M.; Wang, Y.; Bertholet, A. M.; Divakaruni, A. S.
10.1101/2023.08.15.553413 — biochemistry — Posted on 2023-08-16
2282 Integration of Thermal Proteome Profiling with phosphoproteomic and transcriptomic data via mechanistic network models decodes the molecular response to PARP inhibition
Burtscher, M. L.; Gade, S.; Garrido-Rodriguez, M.; Rutkowska, A.; Werner, T.; Eberl, H. C.; Petretich, M.; Knopf, N.; Zirngibl, K.; Grandi, P.; Bergamini, G.; Bantscheff, M.; Faelth-Savitski, M.; Saez-Rodriguez, J.
10.1101/2023.08.15.553354 — systems biology — Posted on 2023-08-16
2284 Predicting host-based, synthetic lethal antiviral targets from omics data
Staheli, J. P.; Neal, M. L.; Navare, A.; Mast, F. D.; Aitchison, J. D.
10.1101/2023.08.15.553430 — bioinformatics — Posted on 2023-08-16
2286 Higher social tolerance is associated with more complex facial behavior in macaques
Rincon, A. V.; Waller, B. M.; Duboscq, J.; Mielke, A.; Perez, C.; Clark, P. R.; Micheletta, J.
10.1101/2022.12.07.519469 — animal behavior and cognition — Posted on 2023-08-16
2287 Whole genome sequencing provides novel insights into the evolutionary history and genetic adaptations of reindeer populations in northern Eurasia
Pokharel, K.; Weldenegodguad, M.; Dudeck, S.; Honkatukia, M.; Lindeberg, H.; Mazzullo, N.; Paasivaara, A.; Peippo, J.; Soppela, P.; Stammler, F.; Kantanen, J.
10.1101/2023.08.16.553162 — genomics — Posted on 2023-08-16
2288 Expanding the Drosophila toolkit for dual control of gene expression
Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J.; Villalta, C.; Forman, C.; Hu, Y.; Mohr, S.; Perrimon, N.
10.1101/2023.08.15.553399 — genetics — Posted on 2023-08-16
2292 The actin binding protein profilin 1 is critical for mitochondria function
Read, T.-A.; Cisterna, B. A.; Skruber, K.; Ahmadieh, S.; Lindamood, H. L.; Vitriol, J. A.; Shi, Y.; Lefebvre, A. E. Y. T.; Black, J. B.; Butler, M. T.; Bear, J. E.; Cherezova, A.; Ilatovskaya, D. V.; Weintraub, N. L.; Vitriol, E. A.
10.1101/2023.08.07.552354 — cell biology — Posted on 2023-08-16
2294 Auxin Exposure Disrupts Feeding Behavior and Fatty Acid Metabolism in Adult Drosophila
Fleck, S. A.; Knuteson, R. L.; Dewitt, E. D.; Eisman, R. C.; Nemkov, T.; D'Alessandro, A.; Tennessen, J. M.; Weaver, L. N.
10.1101/2023.08.15.553385 — physiology — Posted on 2023-08-16
2295 Longer mandible or nose? Co-evolution of feeding organs in early elephantiforms
Li, C.; Deng, T.; Wang, Y.; Sun, F.; Wolff, B.; Jiangzuo, Q.; Ma, J.; Xing, L.; Fu, J.; Zhang, J.; Wang, S.
10.1101/2023.08.15.553347 — paleontology — Posted on 2023-08-16
2298 Modeling individual variability in habitat selection and movement using integrated step-selection analyses
Chatterjee, N.; Wolfson, D.; Kim, D.; Gomez, J. V.; Freeman, S.; Bacheler, N. M.; Shertzer, K.; Taylor, C.; Fieberg, J.
10.1101/2023.07.31.551213 — ecology — Posted on 2023-08-16
2299 Diet influences resource allocation in chemical defence but not melanin synthesis in an aposematic moth
Ottocento, C.; Rojas, B.; Burdfield-Steel, E.; Furlanetto, M.; Nokelainen, O.; Winters, S.; Mappes, J.
10.1101/2023.02.24.529866 — ecology — Posted on 2023-08-16
2301 Cataloging Viral Diversity from Nonaxenic Terrestrial Cyanobacteria Cultures
Ettinger, C. L.; Paul, S. R.; Flores, N.; Ward, R. D.; Pietrasiak, N.; Stajich, J. E.
10.1101/2022.12.14.520320 — microbiology — Posted on 2023-08-16
2302 Dabrafenib alters MDSC differentiation and function by activation of GCN2
Ciudad, M. T.; Quevedo, R.; Lamorte, S.; Jin, R.; Nzirorera, N.; Koritzinsky, M.; McGaha, T. L.
10.1101/2023.08.09.552588 — immunology — Posted on 2023-08-16
2304 Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits
Bian, C.; Demirer, G. S.; Oz, M. T.; Cai, Y.; Witham, S.; Mason, G. A.; Shen, R.; Gaudinier, A.; Brady, S.; Patron, N.
10.1101/2023.07.17.549299 — plant biology — Posted on 2023-08-16
2305 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting
Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.
10.1101/2022.06.23.497372 — bioengineering — Posted on 2023-08-16
2306 The spreading of facultative H3K9me3-heterochromatin drives congenital disease
Chen, W.; Wei, Z.; Xue-Lin, C.; Wen-Fei, W.; Yong-Hao, L.; Jian-Feng, C.; Xiao-Bo, G.; Yuan-Ya, J.; Ya-Bin, L.; Xin-YI, L.; Yu-Tong, L.; Kai, L.; Jian-Quan, N.; Fang-Lin, S.
10.1101/2023.08.11.552907 — genetics — Posted on 2023-08-16
2309 Diatoms exhibit dynamic chloroplast calcium signals in response to high light and oxidative stress
flori, s.; Dickenson, J.; Gaikwad, T.; Cole, I.; Smirnoff, N.; Helliwell, K. E.; Brownlee, C.; Wheeler, G. L.
10.1101/2023.08.15.553405 — plant biology — Posted on 2023-08-16
2310 The Auxin Response Factor ARF27 is required for maize root morphogenesis
Dash, L.; McReynolds, M. R.; Draves, M. A.; Khangura, R. S.; Muench, R. L.; Khor, J.; Cowling, C. L.; Callwood, J. B.; Mejia, L.; Lang, M.; Dilkes, B. P.; Walley, J. W.; Kelley, D. R.
10.1101/2023.08.15.553439 — plant biology — Posted on 2023-08-16
2311 Integrative phenotypic-transcriptomic analysis of soybean plants subjected to multifactorial stress combination
Pelaez-Vico, M. A.; Sinha, R.; Induri, S. P.; Lyu, Z.; Venigalla, S. D.; Vasireddy, D.; Singh, P.; Immadi, M. S.; Pascual, L. S.; Shostak, B.; Mendoza, D. G.; Joshi, T.; Fritschi, F. B.; Zandalinas, S. I.; Mittler, R.
10.1101/2023.08.15.553447 — plant biology — Posted on 2023-08-16
2312 A Pooled Cell Painting CRISPR Screening Platform Enables de novo Inference of Gene Function by Self-supervised Deep Learning
Sivanandan, S.; Leitmann, B.; Lubeck, E.; Sultan, M. M.; Stanitsas, P.; Ranu, N.; Ewer, A.; Mancuso, J. E.; Phillips, Z. F.; Kim, A.; Bisognano, J. W.; Cesarek, J.; Ruggiu, F.; Feldman, D.; Koller, D.; Sharon, E.; Kaykas, A.; Salick, M. R.; Chu, C.
10.1101/2023.08.13.553051 — genomics — Posted on 2023-08-16
2318 The longitudinal single-cell panorama of cynomolgus monkey ovary throughout lifespan revealed a conserved ovarian clock between primates
Yan, L.; Long, X.; Zhao, Y.; Zhao, F.; Tu, W.; Yang, Q.; Qian, J.; Zhai, J.; Wang, M.; Hu, Y.; He, B.; Su, Y.; Jiang, X.; Gao, F.; Wang, H.; Guo, F.
10.1101/2023.08.14.553309 — developmental biology — Posted on 2023-08-16
2319 Nucleotide sharing through gap junctions buffers replication stress
Boumard, B.; Le Meur, G.; Maalouf, T.; El-Hajj, M.; Bauer, R.; Bardin, A. J.
10.1101/2023.08.15.553366 — developmental biology — Posted on 2023-08-16
2320 Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish
Morooka, N.; Gui, N.; Ando, K.; Sako, K.; Fukumoto, M.; Hussmann, M.; Schulte-Merker, S.; Mochizuki, N.; Nakajima, H.
10.1101/2023.08.16.553481 — developmental biology — Posted on 2023-08-16
2322 Lymphotoxin-β Promotes Bone Colonization and Osteolytic Outgrowth of Indolent Bone Metastatic cells of Breast Cancer
Wang, X.; Zhang, T.; Zheng, B.; Lu, Y.; Liang, Y.; Xu, G.; Zhao, L.; Tao, Y.; Song, Q.; You, H.; Hu, H.; Li, X.; Sun, K.; Li, T.; Zhang, Z.; Wang, J.; Lan, X.; Pan, D.; Fu, Y.-X.; Yue, B.; Zheng, H.
10.1101/2023.08.15.553179 — cell biology — Posted on 2023-08-16
2323 Wiskott-Aldrich Syndrome Protein Regulates Nucleolar Organization and Function in Innate Immune Response
Zhou, X.; Yuan, B.; Tian, Y.; Zhou, J.; Wang, M.; shakir, I.; Zhang, Y.; Bi, C.; Aljamal, B. M.; Hashem, M. O.; Abuyousef, O. I.; Abdulwahab, F. M.; Ali, A.; Dunn, S.; Moresco, J.; Yates, J. R.; Frassoni, F.; Gao, X.; Alkuraya, F.; Belmonte, J. C. I.; Li, M.
10.1101/2023.08.15.553387 — cell biology — Posted on 2023-08-16
2325 Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton
Yamamoto, T.; Ishibashi, T.; Mimori-Kiyosue, Y.; Hiver, S.; Tokushige, N.; Tarama, M.; Takeichi, M.; Shibata, T.
10.1101/2023.08.16.553476 — cell biology — Posted on 2023-08-16
2326 EWSR1's visual modalities are defined by its association with nucleic acids and RNA polymerase II
Sundara Rajan, S.; Ebegboni, V. J.; Pichling, P.; Ludwig, K. R.; Jones, T. L.; Chari, R.; Tran, A. D.; Kruhlak, M. J.; Loncarek, J.; Caplen, N. J.
10.1101/2023.08.16.553246 — cell biology — Posted on 2023-08-16
2328 Landscape drives zoonotic malaria prevalence in non-human primates
Johnson, E.; Sunil Kumar Sharma, R.; Ruiz Cuenca, P.; Byrne, I.; Salgado-Lynn, M.; Suraya Shahar, Z.; Col Lin, L.; Zulkifli, N.; Dilaila Mohd Saidi, N.; Drakeley, C.; Matthiopoulos, J.; Nelli, L.; Fornace, K.
10.1101/2022.06.17.496284 — ecology — Posted on 2023-08-16
2330 Designer small molecule control system based on Minocycline induced disruption of protein-protein interaction.
Jha, R.; Kinna, A.; Hotblack, A.; Bughda, R.; Bulek, A.; Gannon, I.; Ilca, T.; Allen, C.; Lamb, K.; Dolor, A.; Parekh, F.; Sillibourne, J.; Cordoba, S. P.; Onuoha, S. C.; Thomas, S.; Ferrari, M.; Pule, M.
10.1101/2023.08.15.553207 — molecular biology — Posted on 2023-08-16
2331 Iron Regulatory Protein 1 is Required for the Propagation of Inflammation in Inflammatory Bowel Disease
Fahoum, L.; Belizowsky, S.; Ghatpande, N.; Guttmann-Raviv, N.; Zhang, W.; Kuanyu, L.; Wing-Hang, T.; Nyska, A.; Waterman, M.; Weisshof, R.; Zukirman, A.; Meyron-Holtz, E.
10.1101/2023.01.27.525690 — immunology — Posted on 2023-08-16
2332 Neonatal brain dynamic functional connectivity: impact of preterm birth and association with early childhood neurodevelopment
Franca, L. G. S.; Ciarrusta, J.; Gale-Grant, O.; Fenn-Moltu, S.; Fitzgibbon, S. P.; Chew, A.; Falconer, S.; Dimitrova, R.; Cordero-Grande, L.; Price, A. N.; Hughes, E.; O'Muircheartaigh, J.; Duff, E.; Tuulari, J. J.; Deco, G.; Counsell, S. J.; Hajnal, J. V.; Nosarti, C.; Arichi, T.; Edwards, D.; McAlonan, G.; Batalle, D.
10.1101/2022.11.16.516610 — neuroscience — Posted on 2023-08-16
2333 Meningeal IL-17 producing T cells mediate cognitive impairment in salt-sensitive hypertension
Santisteban, M. M.; Schaeffer, S.; Anfray, A.; Faraco, G.; Brea Lopez, D.; Wang, G.; Sobanko, M. J.; Sciortino, R.; Racchumi, G.; Waisman, A.; Park, L.; Anrather, J.; Iadecola, C.
10.1101/2022.09.05.506398 — neuroscience — Posted on 2023-08-16
2337 FCS-Like Zinc finger 14 (FLZ14) mediates the crosstalk between TORC and SnRK1 in response to sugar availability.
Artins, A.; Urrea Castellanos, R.; Martin-Sanchez, M.; Alexandre Moraes, T.; Fernie, A. R.; Satake, A.; Caldana, C.
10.1101/2023.08.14.553285 — plant biology — Posted on 2023-08-16
2338 Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer
Zhao, G.; Forn-Cuni, G.; Scheers, M.; Lindenbergh, P. P.; Yin, J.; van Loosen, Q.; Passarini, L.; Chen, L.; Snaar, E. B.
10.1101/2023.08.14.553275 — cancer biology — Posted on 2023-08-16
2341 Robust collection and processing for label-free single voxel proteomics
Kitata, R.; Velickovic, M.; Xu, Z.; Zhao, R.; Scholten, D.; Chu, R.; Orton, D.; Chrisler, W.; Mathews, J.; Piehowski, P. D.; Liu, T.; Smith, R.; liu, H.; Wasserfall, C.; Tsai, C.-F.; Shi, T.
10.1101/2023.08.14.553333 — molecular biology — Posted on 2023-08-16
2343 Adipose contributes to CXCL5 regulated immune evasion in pancreatic cancer
Walsh, R. M.; Ambrose, J.; Messaggio, F.; Bye, B.; Eades, A.; Jack, J.; Ruckert, M.; Olou, A.; Chalise, P.; Pei, D.; VanSaun, M.
10.1101/2023.08.15.553432 — cancer biology — Posted on 2023-08-16
2345 Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer
Pan, J.-W.; Tan, Z.-C.; Ng, P.-S.; Zabidi, M. M. A.; Nur Fatin, P.; Teo, J.-Y.; Hasan, S. N.; Islam, T.; Teoh, L.-Y.; Jamaris, S.; See, M.-H.; Yip, C.-H.; Rajadurai, P.; Looi, L.-M.; Taib, A. M.; Rueda, O. M.; Caldas, C.; Chin, S.-F.; Lim, J. M. C.; Teo, S.-H.
10.1101/2022.06.08.495296 — cancer biology — Posted on 2023-08-16
2347 Network shape intelligence outperforms AlphaFold2 intelligence in vanilla protein interaction prediction.
Abdelhamid, I.; Muscoloni, A.; Rotscher, D. M.; Lieber, M.; Markwardt, U.; Cannistraci, C. V.
10.1101/2023.08.10.552825 — bioinformatics — Posted on 2023-08-16
2350 Quantifying collective interactions in biomolecular phase separation
Ausserwoeger, H.; Qian, D.; Krainer, G.; de Csillery, E.; Welsh, T. J.; Sneideris, T.; Franzmann, T. M.; Qamar, S. S.; Erkamp, N. A.; Nixon-Abell, J.; Kar, M.; St George-Hyslop, P.; Hyman, A. A.; Alberti, S.; Pappu, R. V.; Knowles, T. P. J.
10.1101/2023.05.31.543137 — biophysics — Posted on 2023-08-16
2351 Mechanism of substrate binding and transport in BASS transporters
Becker, P.; Naughton, F. B.; Brotherton, D. H.; Pacheco-Gomez, R.; Beckstein, O.; Cameron, A. D.
10.1101/2023.06.02.543391 — biochemistry — Posted on 2023-08-16
2352 Spring reproductive success influences autumnal malarial load in a passerine bird
Pigeault, R.; Cozzarolo, C.-S.; Wassef, J.; Gremion, J.; Bastardot, M.; Glaizot, O.; Christe, P.
10.1101/2023.07.28.550923 — ecology — Posted on 2023-08-16
2354 Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
Ang, Z.; Paruzzo, L.; Hayer, K. E.; Schmidt, C.; Torres Diz, M.; Xu, F.; Zankharia, U.; Zhang, Y.; Soldan, S.; Zheng, S.; Falkenstein, C. D.; Loftus, J. P.; Yang, S. Y.; Asnani, M.; King Sainos, P.; Pillai, V.; Chong, E.; Li, M. M.; Tasian, S. K.; Barash, Y.; Lieberman, P. M.; Ruella, M.; Schuster, S. J.; Thomas-Tikhonenko, A.
10.1101/2023.02.19.529123 — immunology — Posted on 2023-08-16
2360 Comparison of colorimetric, fluorometric, and liquid chromatography-mass spectrometry assays for acetyl-coenzyme A
Kantner, D. S.; Megill, E.; Bostwick, A.; Yang, V.; Bekeova, C.; Van Scoyk, A.; Seifert, E.; Deininger, M. W.; Snyder, N. W.
10.1101/2023.06.01.543311 — biochemistry — Posted on 2023-08-16
2361 Genomic DNA extraction optimization and validation for genome sequencing using the marine gastropod Kellet's whelk
Daniels, B. N.; Nurge, J.; Sleeper, O.; Lee, A.; Lopez, C.; Christie, M.; Toonen, R. J.; Davidson, J.; White, C.
10.1101/2023.07.31.551321 — genomics — Posted on 2023-08-16
2363 Subcytoplasmic location of translation controls protein output
Horste, E. L.; Fansler, M. M.; Cai, T.; Chen, X.; Mitschka, S.; Zhen, G.; Lee, F. C. Y.; Ule, J.; Mayr, C.
10.1101/2022.11.04.515216 — molecular biology — Posted on 2023-08-16
2365 Early life high fructose exposure disrupts microglia function and impedes neurodevelopment
Wang, Z.; Lipschutz, A.; Liu, Z.-L.; Trzeciak, A.; Miranda, I.; Martinez de la Torre, C.; Schild, T.; Lazarov, T.; Rojas, W. S.; Saavedra, P.; Romero-Pichardo, J.; Baako, A.; Geissmann, F.; Faraco, G.; Gan, L.; Etchegaray, J. I.; Lucas, C.; Parkhurst, C.; Zeng, M.; Keshari, K.; Perry, J.
10.1101/2023.08.14.553242 — immunology — Posted on 2023-08-16
2366 Maternal obesity programs hypothalamic miR-505-5p expression in mouse offspring and impacts hypothalamic fatty acid sensing
Furigo, I. C.; Pantaleao, L. C.; de Almeida-Faria, J.; Kentistou, K. A.; Wong, L. W.-P.; Carreira, M. V.; Bidault, G.; Vidal-Puig, A.; Ong, K. K.; Perry, J. R.; Donato, J.; Dearden, L.; Ozanne, S. E.
10.1101/2022.06.01.494310 — neuroscience — Posted on 2023-08-16
2367 Does phasic dopamine release cause policy updates?
Carter, F.; Cossette, M.-P.; Trujillo-Pisanty, I.; Pallikaras, V.; Breton, Y.-A.; Conover, K.; Caplan, J.; Solis, P.; Voisard, J.; Yaksich, A.; Shizgal, P.
10.1101/2022.08.08.502043 — neuroscience — Posted on 2023-08-16
2368 Dissociation of direct and peripheral transcranial magnetic stimulation effects in nonhuman primates
Perera, N. D.; Alekseichuk, I.; Shirinpour, S.; Wischnewski, M.; Linn, G.; Masiello, K.; Butler, B.; Russ, B. E.; Schroeder, C. E.; Falchier, A.; Opitz, A.
10.1101/2022.12.26.521973 — neuroscience — Posted on 2023-08-16
2369 Spatial extent of within-thalamus cortical connections varies across the cortical hierarchy in humans and macaques
Howell, A. M.; Warrington, S.; Fonteneau, C.; Cho, Y.; Sotiropoulos, S.; Murray, J. D.; Anticevic, A.
10.1101/2023.07.22.550168 — neuroscience — Posted on 2023-08-16
2370 Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
Dolcemascolo, R.; Heras-Herandez, M.; Goiriz, L.; Montagud-Martinez, R.; Requena-Menendez, A.; Ruiz, R.; Perez-Rafols, A.; Higuera-Rodriguez, R. A.; Perez-Ropero, G.; Vranken, W. F.; Martelli, T.; Kaiser, W.; Buijs, J.; Rodrigo, G.
10.1101/2022.11.22.516435 — synthetic biology — Posted on 2023-08-16
2372 The CB1 Negative Allosteric Modulator PSNCBAM-1 Reduces Ethanol Self-Administration via a Nonspecific Hypophagic Effect
Buechler, H. M.; Sumi, M.; Madhurathakam, I. M.; Donegan, C.; DiGiorgio, F.; Acosta, A.; Uribe, S.; Rahman, M. A.; Sorbello, A.; Fischer, B. D.; Keck, T. M.
10.1101/2023.06.30.547272 — pharmacology and toxicology — Posted on 2023-08-16
2373 Robust somatic copy number estimation using coarse-to-fine segmentation
Culibrk, L.; Grewal, J. K.; Pleasance, E. D.; Williamson, L.; Mungall, K.; Laskin, J.; Marra, M. A.; Jones, S. J.
10.1101/2021.08.06.455329 — cancer biology — Posted on 2023-08-15
2374 MousiPLIER: A Mouse Pathway-Level Information Extractor Model
Zhang, S.; Heil, B. J.; Mao, W.; Chikina, M.; Greene, C. S.; Heller, E. A.
10.1101/2023.07.31.551386 — bioinformatics — Posted on 2023-08-15
2376 Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration
Offeddu, G. S.; Cambria, E.; Shelton, S. E.; Wan, Z.; Haase, K.; Possenti, L.; Nguyen, H. T.; Gillrie, M. R.; Hickman, D.; Knutson, C. G.; Kamm, R. D.
10.1101/2021.12.12.472296 — bioengineering — Posted on 2023-08-16
2377 Characterization of TGFβ-induced tendon-like structure in scaffold-free three-dimensional tendon cell culture
Koo, B.-h.; Lee, Y.; Park, N. R.; Heo, S.-J.; Hudson, D. M.; Fernandes, A. A.; Friday, C. S.; Hast, M. W.; Corr, D. T.; Keene, D. R.; Tufa, S. F.; Dyment, N. A.; Joeng, K. S.
10.1101/2022.06.08.495368 — bioengineering — Posted on 2023-08-16
2378 Patterning and folding of intestinal villi by active mesenchymal dewetting
Huycke, T. R.; Miyazaki, H.; Häkkinen, T.; Srivastava, V.; Barruet, E.; McGinnis, C. S.; Kalantari, A.; Cornwall-Scoones, J.; Vaka, D.; Zhu, Q.; Jo, H.; DeGrado, W. F.; Thomson, M.; Garikipati, K.; Boffelli, D.; Klein, O. D.; Gartner, Z. J.
10.1101/2023.06.25.546328 — developmental biology — Posted on 2023-08-15
2384 Tazobactam selects for multidrug resistance
Holden, E. R.; Yasir, M.; Turner, A. K.; Charles, I. G.; Webber, M. A.
10.1101/2023.08.15.553388 — molecular biology — Posted on 2023-08-15
2388 Enhancing CRISPR prime editing by reducing misfolded pegRNA interactions
Zhang, W.; Petri, K.; Ma, J.; Lee, H.; Tsai, C.-L.; Joung, J. K.; Yeh, J.-R. J.
10.1101/2023.08.14.553324 — genomics — Posted on 2023-08-15
2389 Deletion of Xist upstream sequences alters TAD interactions and leads to defects in Xist coating and expression
Majumdar, S.; Bammidi, L. S.; Naik, H.; M, A.; Baro, R.; Kalita, A.; Sundarraj, N.; Bariha, G.; Notani, D.; GAYEN, S.
10.1101/2023.08.14.553118 — genetics — Posted on 2023-08-15
2390 Epithelial Ca2+ waves triggered by enteric neurons heal the gut
Petsakou, A.; Liu, Y.; Liu, Y.; Comjean, A.; Hu, Y.; Perrimon, N.
10.1101/2023.08.14.553227 — genetics — Posted on 2023-08-15
2392 Palaeoproteomic investigation of an ancient human skeleton with abnormal deposition of dental calculus
Uchida-Fukuhara, Y.; Shimamura, S.; Sawafuji, R.; Nishiuchi, T.; Yoneda, M.; Ishida, H.; Matsumura, H.; Tsutaya, T.
10.1101/2023.08.15.553159 — evolutionary biology — Posted on 2023-08-15
2393 An atypical basement membrane forms a midline barrier in left-right asymmetric gut development
Demler, C. A.; Lawlor, J. C.; Yelin, R.; Llivichuzcha-Loja, D.; Shaulov, L.; Kim, D. S.; Stewart, M. A.; Lee, F.; Schultheiss, T. M.; Kurpios, N. A.
10.1101/2023.08.15.553395 — developmental biology — Posted on 2023-08-15
2395 TGF-β1 inhibits cholesterol metabolism in hepatocytes to facilitate cell death, EMT and signals for HSC activation.
Wang, S.; Link, F.; Han, M.; Liebe, R.; Yao, Y.; Hammad, S.; Dropmann, A.; Chaudhary, R.; Asimakopoulos, A.; Krizanac, M.; Weiskirchen, R.; Henis, Y. I.; Ehrlich, M.; Ebert, M.; Dooley, S.
10.1101/2023.08.14.552900 — cell biology — Posted on 2023-08-15
2396 Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex
Guo, Q.; Chen, K.-E.; Gimenez-Andres, M.; Jellett, A.; Gao, Y.; Simonetti, B.; Liu, M.; Danson, C.; Heesom, K. J.; Cullen, P. J.; Collins, B. M.
10.1101/2023.08.15.553351 — cell biology — Posted on 2023-08-15
2398 An anciently diverged family of RNA binding proteins maintain correct splicing of ultra-long exons through cryptic splice site repression.
Siachisumo, C.; Luzzi, S.; Aldalaqan, S.; Hysenaj, G.; Dalgliesh, C.; Cheung, K.; Gazzara, M. R.; Yonchev, I. D.; James, K.; Kheirollahi Chadegani, M.; Ehrmann, I. E.; Smith, G. R.; Cockell, S. J.; Munkley, J.; wilson, s. a.; Barash, Y.; Elliott, D.
10.1101/2023.08.15.553384 — molecular biology — Posted on 2023-08-15
2399 A non-canonical mechanism of GPCR activation
Powers, A. S.; Khan, A.; Paggi, J. M.; Latorraca, N. R.; Souza, S.; Di Salvo, J.; Lu, J.; Soisson, S. M.; Johnston, J. M.; Weinglass, A. B.; Dror, R. O.
10.1101/2023.08.14.553154 — molecular biology — Posted on 2023-08-15
2401 SARS-CoV-2 infection triggers pro-atherogenic inflammatory 1 responses in human coronary vessels
Eberhardt, N.; Noval, M. G.; Kaur, R.; Sajja, S.; Amadori, L.; Das, D.; Cilhoroz, B.; Stewart, O. J.; Fernandez, D. M.; Shamailova, R.; Guillen, A. V.; Jangra, S.; Schotsaert, M.; Gildea, M.; Newman, J. D.; Faries, P.; Maldonado, T.; Rockman, C.; Rapkiewicz, A.; Stapleford, K. A.; Narula, N.; Moore, K. J.; Giannarelli, C.
10.1101/2023.08.14.553245 — immunology — Posted on 2023-08-15
2402 HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent
Wang, L.; Unterreiner, A.; Kapetanovic, R.; Aslani, S.; Xiong, Y.; Donovand, K. A.; Farady, C. J.; Fischer, E. S.; Bornancinc, F.; Matthias, P.
10.1101/2023.08.15.553363 — immunology — Posted on 2023-08-15
2403 High-throughput generic single-entity sequencing using droplet microfluidics
Wang, G.; Zhao, L.; Shi, Y.; Qu, F.; Ding, Y.; Liu, W.; Liu, C.; Luo, G.; Li, M.; Bai, X.; Li, L.; Ho, Y.-P.; Yu, J.
10.1101/2023.08.15.549386 — bioengineering — Posted on 2023-08-15
2405 Integrated spatial transcriptomics and lipidomics of precursor lesions of pancreatic cancer identifies enrichment of long chain sulfatide biosynthesis as an early metabolic alteration
Sans, M.; Chen, Y.; Thege, F. I.; Dou, R.; Min, J.; Yip-Schneider, M.; Zhang, J.; Wu, R.; Irajizad, E.; Makino, Y.; Rajapakshe, K. I.; Hurd, M. W.; Leon, R. A.; Vykoukal, J.; Dennison, J. B.; Do, K.-a.; Wolff, R. A.; Guerrero, P. A.; Kim, M. P.; Schmidt, C. M.; Maitra, A.; Hanash, S.; Fahrmann, J. F.
10.1101/2023.08.14.553002 — cancer biology — Posted on 2023-08-15
2406 Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life
Lazar-Contes, I.; Tanwar, D. K.; Arzate-Mejia, R.; Steg, L.; Crespo, M.; Feudjio, O.; Germain, P.-L.; Mansuy, I. M.
10.1101/2020.08.20.259374 — developmental biology — Posted on 2023-08-15
2407 Within-species variation in the gut microbiome of medaka (Oryzias latipes) is driven by the interaction of light intensity and genetic background
Evangelista, C.; Kamenova, S.; Diaz Pauli, B.; Sandkjenn, J.; Vollestad, A.; Edeline, E.; Trosvik, P.; de Muinck, E.
10.1101/2023.02.17.528956 — ecology — Posted on 2023-08-15
2409 Mutagenic-end joining results in smaller deletions in heterochromatin relative to euchromatin
Miller, J. M.; Prange, S.; Ji, H.; Rau, A. R.; Khodaverdian, V. Y.; Li, X.; Patel, A.; Butova, N. L.; Lutter, A.; Chung, H.; Merigliano, C.; Rawal, C. C.; Hanscom, T.; McVey, M.; Chiolo, I.
10.1101/2023.03.03.531058 — cell biology — Posted on 2023-08-15
2410 Gene editing in the Chagas disease vector Rhodnius prolixus by Cas9-mediated ReMOT Control
Lima, L.; Berni, M.; Mota, J.; Bressan, D.; Julio, A.; Cavalcante, R.; Macias, V.; Li, Z.; Rasgon, J. L.; Bier, E.; Araujo, H. M.
10.1101/2023.08.14.553172 — molecular biology — Posted on 2023-08-15
2413 FAVA: High-quality functional association networks inferred from scRNA-seq and proteomics data
Koutrouli, M.; Lindez, P. P.; Nastou, K.; Bouwmeester, R.; Rasmussen, S.; Martens, L.; Jensen, L. J.
10.1101/2022.07.06.499022 — bioinformatics — Posted on 2023-08-15
2416 Linking metabolic scaling and coexistence theories
Saavedra, S.; Arroyo, J. I.; Marquet, P.; Kempes, C.
10.1101/2023.02.28.530509 — ecology — Posted on 2023-08-15
2418 Network structure influences the strength of learned neural representations
Kahn, A. E.; Szymula, K.; Loman, S.; Nyema, N.; Haggerty, E. B.; Aguirre, G. K.; Bassett, D. S.
10.1101/2023.01.23.525254 — neuroscience — Posted on 2023-08-15
2419 Synaptotagmin 7 transiently docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release
Wu, Z.; Kusick, G. F.; Berns, M. M. M.; Raychaudhuri, S.; Itoh, K.; Walter, A. M.; Chapman, E. R.; Watanabe, S.
10.1101/2022.04.21.489101 — neuroscience — Posted on 2023-08-15
2420 Characterizing the diversity of enteric neurons using Dopamine Transporter (DAT)-Cre reporter mice
Recinto, S.; Premachandran, S.; Mukherjee, S.; McDonald, A.; Gruenheid, S.; Trudeau, L. E.; Stratton, J. A.
10.1101/2023.06.16.545271 — neuroscience — Posted on 2023-08-15
2422 A Pooled Cell Painting CRISPR Screening Platform Enables de novo Inference of Gene Function by Self-supervised Deep Learning
Sivanandan, S.; Leitmann, B.; Lubeck, E.; Sultan, M. M.; Stanitsas, P.; Ranu, N.; Ewer, A.; Mancuso, J. E.; Phillips, Z. F.; Kim, A.; Bisognano, J. W.; Cesarek, J.; Ruggiu, F.; Feldman, D.; Koller, D.; Sharon, E.; Kaykas, A.; Salick, M. R.; Chu, C.
10.1101/2023.08.13.553051 — genomics — Posted on 2023-08-15
2423 Early life high fructose exposure disrupts microglia function and impedes neurodevelopment
Perry, J.; Wang, Z.; Lipschutz, A.; Liu, Z.-L.; Trzeciak, A.; Miranda, I.; Martinez de la Torre, C.; Schild, T.; Lazarov, T.; Rojas, W. S.; Saavedra, P.; Romero-Pichardo, J.; Baako, A.; Geissmann, F.; Faraco, G.; Gan, L.; Etchegaray, J. I.; Lucas, C.; Parkhurst, C.; Zeng, M.; Keshari, K.
10.1101/2023.08.14.553242 — immunology — Posted on 2023-08-15
2424 Mechanical force regulates ligand binding and function of PD-1
Li, K.; Cardenas-Lizana, P.; Kellner, A. V.; Yuan, Z.; Ahn, E.; Lyu, J.; Li, Z.; Salaita, K.; Ahmed, R.; Zhu, C.
10.1101/2023.08.13.553152 — immunology — Posted on 2023-08-15
2427 The Spatial Patterns and Determinants of Cerebrospinal Fluid Circulation in the Human Brain
Nazeri, A.; Dehkharghanian, T.; Lindsay, K. E.; LaMontagne, P. J.; Shimony, J. S.; Benzinger, T. L. S.; Sotiras, A.
10.1101/2023.08.13.553149 — neuroscience — Posted on 2023-08-15
2429 CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism
Xu, M.; Neelands, T.; Powers, A. S.; Liu, Y.; Miller, S. D.; Pintilie, G.; Du Bois, J.; Dror, R. O.; Chiu, W.; Maduke, M.
10.1101/2023.08.13.553136 — biophysics — Posted on 2023-08-15
2435 Meteora sporadica, a protist with incredible cell architecture, is related to Hemimastigophora.
Eglit, Y.; Shiratori, T.; Jerlström-Hultqvist, J.; Williamson, K.; Roger, A. J.; Ishida, K.-I.; Simpson, A. G. B.
10.1101/2023.08.13.553137 — evolutionary biology — Posted on 2023-08-15
2437 Lymphatic vessel development in human embryos
Yamaguchi, S.; Minamide, N.; Imai, H.; Ikeda, T.; Watanabe, M.; Imanaka-Yoshida, K.; Maruyama, K.
10.1101/2023.08.12.553102 — developmental biology — Posted on 2023-08-15
2439 F-box protein FBXB-65 regulates anterograde transport of UNC-104 through modification near the PH domain
Sabharwal, V.; Boyanapalli, S. P. P.; Shee, A.; Nonet, M. L.; Nandi, A.; Chaudhuri, D.; Koushika, S. P.
10.1101/2023.08.13.553108 — cell biology — Posted on 2023-08-15
2440 A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint
Heieis, G. A.; Everts, B.; Roberts, C. W.; Maizels, R. M.; Perona-Wright, G.
10.1101/2023.08.13.553117 — immunology — Posted on 2023-08-15
2441 MidRISH: Unbiased harmonization of rotationally invariant harmonics of the diffusion signal
Newlin, N. R.; Kim, M. E.; Kanakaraj, P.; Yao, T.; Hohman, T.; Pechman, K. R.; Beason-Held, L.; Resnick, S. M.; Archer, D. B.; Jefferson, A.; Landman, B. A.; Moyer, D.
10.1101/2023.08.12.553099 — neuroscience — Posted on 2023-08-15
2442 Neural correlates of confidence during decision formation in a perceptual judgment task
Ko, Y. H.; Zhou, A.; Niessen, E.; Stahl, J.; Weiss, P. H.; Hester, R.; Bode, S.; Feuerriegel, D. C.
10.1101/2023.08.13.553156 — neuroscience — Posted on 2023-08-15
2443 The interplay between focus of attention, respiratory phases, and the Heartbeat Evoked Potential
Zaccaro, A.; della Penna, F.; Mussini, E.; Parrotta, E.; Perrucci, M. G.; Costantini, M.; Ferri, F.
10.1101/2023.08.13.553126 — neuroscience — Posted on 2023-08-15
2445 Reduced brain glutathione levels during normal aging are associated with visuospatial memory
Hu, X.; Pan, K.; Zhao, M.; Lv, J.; Wang, J.; Zhang, X.; Liu, Y.; Song, y.; Gudmundson, A. T.; Edden, R. A. E.; Ren, F.; Zhang, T.; gao, f.
10.1101/2023.08.13.553100 — neuroscience — Posted on 2023-08-15
2446 Parental effects provide an opportunity for coral resilience following major bleaching events
Lenz, E.; Donahue, M. J.; van der Steeg, E.; Gates, R.; Putnam, H.; Padilla-Gamino, J.
10.1101/2023.08.09.552721 — zoology — Posted on 2023-08-15
2451 TIGIT drives the immunosuppressive environment by downregulation of metalloproteinases MMP2 and MMP14 in perihilar cholangiocarcinoma.
Heij, L.; Reichel, K.; de Koning, W.; Bednarsch, J.; Tan, X.; Campello Deierl, J.; Clahsen-van Groningen, M.; Al-Masri, T.; van Dam, R.; Garcia Vallejo, J.; Ulmer, F.; Lang, S.; Luedde, T.; Rocha, F.; Dahl, E.; Jonigk, D.; Kuehnel, M.; Sivakumar, S.; Neumann, U.
10.1101/2023.08.14.553195 — cancer biology — Posted on 2023-08-15
2452 PARG inhibition induces nuclear aggregation of PARylated PARP1
Paradkar, S.; Purcell, J.; Cui, A.; Friedman, S.; Sundaram, R.; Jensen, R. B.; Bindra, R. S.
10.1101/2023.08.12.553088 — cancer biology — Posted on 2023-08-15
2453 Germline mutation rate predicts cancer mortality across 37 vertebrate species
Kapsetaki, S. E.; Compton, Z. T.; Mellon, W.; Vincze, O.; Giraudeau, M. T.; Harrison, T.; Abegglen, L.; Boddy, A.; Maley, C. C.; Schiffman, J.
10.1101/2023.08.13.553123 — cancer biology — Posted on 2023-08-15
2464 Global and local adaptation to aridity in a desert plant Gymnocarpos przewalskii
Fu, R.; Zhu, Y.; Liu, Y.; Yang, Z.; Lu, R.; Qiu, Y.; Lascoux, M.; Li, P.; Chen, J.
10.1101/2023.08.13.553124 — evolutionary biology — Posted on 2023-08-15
2466 Global nuclear reorganization during heterochromatin replication in the giant-genome plant Nigella damascena L.
Arifulin, E.; Sorokin, D.; Anoshina, N.; Kuznetsova, M.; Valyaeva, A.; Fedotova, A.; Schubert, V.; Kolesnikova, T.; Sheval, E.
10.1101/2023.08.15.552960 — cell biology — Posted on 2023-08-15
2467 ORF3c is expressed in SARS-CoV-2 infected cells and suppresses immune activation by inhibiting innate sensing
Mueller, M.; Herrmann, A.; Fujita, S.; Kolberg, J. E.; Kruth, C.; Strange, A.; Schneider, M.; Ito, J.; Ensser, A.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Sato, K.; Sauter, D.
10.1101/2023.02.27.530232 — microbiology — Posted on 2023-08-15
2469 Pseudomonas aeruginosa MipA-MipB envelope proteins act as new sensors of polymyxin
Janet-Maitre, M.; Job, V.; Bour, M.; Brugiere, S. M.; Robert-Genthon, M.; Cobessi, D.; Coute, Y.; Jeannot, K.; Attree, I.
10.1101/2023.08.14.553335 — microbiology — Posted on 2023-08-15
2470 A scalable, low-cost phenotyping strategy to assess tuber size, shape, and the colorimetric features of tuber skin and flesh in potato breeding populations
Feldman, M. J.; Park, J.; Miller, N.; Wakholi, C.; Greene, K.; Abbasi, A.; Rippner, D. A.; Navarre, D.; Carley, C. S.; Shannon, L. M.; Novy, R.
10.1101/2023.08.14.553050 — plant biology — Posted on 2023-08-15
2473 Non-Hebbian plasticity transforms transient experiences into lasting memories
Faress, I.; Khalil, V.; Hou, W.-H.; Moreno, A.; Andersen, N.; Fonseca, R.; Piriz, J.; Capogna, M.; Nabavi, S.
10.1101/2023.04.06.535862 — neuroscience — Posted on 2023-08-15
2475 VISTA: An integrated framework for structural variant discovery
Sarwal, V.; Lee, S.; Yang, J.; Sankararaman, S.; Chaisson, M.; Eskin, E.; Mangul, S.
10.1101/2023.08.11.553053 — bioinformatics — Posted on 2023-08-15
2477 Maternal allergic sensitization affects the T cell modulatory capacity and molecular cargo of milk derived extracellular vesicles
van Herwijnen, M. J. C.; Giovanazzi, A.; Zonneveld, M. I.; Maqueda, J. J.; Kleinjan, M.; Goerdayal, S.; Vollmy, F.; van Bruggen - de Haan, A.; Driedonks, T. A. P.; Arkesteijn, G. J. A.; van Elburg, R. M.; van der Meulen, G. N.; Garssen, J.; Oliveira, C.; Altelaar, A. F. M.; 't Hoen, P. A. C.; Redegeld, F. A.; Nolte- 't Hoen, E. N. M.; Wauben, M. H. M.
10.1101/2023.08.11.553032 — immunology — Posted on 2023-08-15
2479 Selective medial septum lesions in healthy rats induce longitudinal changes in microstructure of limbic regions, behavioral alterations, and increased susceptibility to status epilepticus
Luna-Munguia, H.; Gasca-Martinez, D.; Garay, B. A.; Coutino, D.; Regalado, M.; de los Rios, E.; Villasenor, P.; Hidalgo-Flores, F.; Flores-Guapo, K.; Benito, B. Y.; Concha, L.
10.1101/2023.08.11.553036 — neuroscience — Posted on 2023-08-15
2480 I feel your pain: Higher empathy is associated with higher posterior default mode network activity
Oliva, V.; Riegner, G.; Dean, J.; Khatib, L.; Barrows, D.; Chen, C.; Mosbey, D.; Lopez, C.; Uvarova, A.; Allen, A.; Reyes, M.; Fuentes, R.; Jacobson, A.; Liu, T.; Zeidan, F.
10.1101/2023.08.11.553004 — neuroscience — Posted on 2023-08-15
2481 A neuronal relay mediates muscle-adipose communication that drives systemic metabolic adaptation to high-sugar diets
Kubrak, O.; Joergensen, A. F.; Koyama, T.; Nagy, S.; Lassen, M.; Hald, J.; Madsen, D.; Halberg, K. V.; Texada, M. J.; Hansen, J. L.; Rewitz, K.
10.1101/2023.08.15.553340 — physiology — Posted on 2023-08-15
2482 Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial
Zhang, S.; Deshpande, A.; Verma, B. K.; Wang, H.; Mi, H.; Yuan, L.; Ho, W. J.; Jaffee, E. M.; Zhu, Q.; Anders, R. A.; Yarchoan, M.; Kagohara, L. T.; Fertig, E. J.; Popel, A. S.
10.1101/2023.08.11.553000 — bioengineering — Posted on 2023-08-15
2483 Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Kamei, S.; Mayooramurugan, S.; Abbott, L. R.; Hasan, A.; Bueno-Alejo, C.; Sukegawa, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2023-08-15
2485 Integrative multi-omics increases resolution of the sea urchin posterior hindgut at cell type resolution
Voronov, D.; Paganos, P.; Magri, M. S.; Cuomo, C.; Maeso, I.; Gomez-Skarmeta, J. L.; Arnone, M. I.
10.1101/2023.05.12.540495 — developmental biology — Posted on 2023-08-15
2486 The dynamics of hinge flexibility in receptor bound immunoglobulin E revealed by electron microscopy
Jensen, R. K.; Miehe, M.; Gandini, R.; Joergensen, M. H.; Spillner, E.; Andersen, G. R.
10.1101/2023.02.17.528943 — immunology — Posted on 2023-08-15
2487 Percutaneous Intramyocardial Septal Cryoablation: A Canine Model with 6 months Follow-up
Lu, X.; Li, J.; Hsi, D. H.; Zhang, J.; Han, Y.; Tuo, S.; Wang, J.; He, J.; Zhao, J.; Han, C.; Yao, L.; Ou, X.; Shan, B.; Wang, B.; Zhao, X.; Hu, R.; Liu, L.-W.
10.1101/2023.08.08.552550 — zoology — Posted on 2023-08-15
2490 Prevotella copri-linked effects of a therapeutic food for malnutrition
Gordon, J.; Wang, Y.; Chang, H.-W.; Lee, E. M.; Zhou, C.; Pruss, K. M.; Henrissat, S.; Chen, R. Y.; Kao, C.; Hibberd, M. C.; Lynn, H. M.; Webber, D. M.; Crane, M.; Cheng, J.; Rodionov, D. A.; Arzamasov, A. A.; Castillo, J. J.; Couture, G.; Chen, Y.; Balcazo, N. P.; Lebrilla, C. B.; Terrapon, N.; Henrissat, B.; Ilkayeva, O.; Muehlbauer, M. J.; Newgard, C.; Mostafa, I.; Das, S.; Mahfuz, M.; Osterman, A.; Barratt, M. J.; Ahmed, T.
10.1101/2023.08.11.553030 — microbiology — Posted on 2023-08-15
2491 WOX11-mediated adventitious lateral root formation modulates tolerance of Arabidopsis to cyst nematode infections
Willig, J.-J.; Guarneri, N.; van Loon, T.; Wahyuni, S.; Astudillo-Estevez, I. E.; Xu, L.; Willemsen, V.; Goverse, A.; Sterken, M. G.; Lozano-Torres, J. L.; Bakker, J.; Smant, G.
10.1101/2023.08.11.553027 — plant biology — Posted on 2023-08-15
2498 Shared and distinct molecular effects of regulatory genomic variants provide insight into mechanisms of distal enhancer-promoter communication
Ray-Jones, H.; Song, Z.; Haglund, A.; Artemov, P.; Della Rosa, M.; Burden, F.; Kreuzhuber, R.; Litovskikh, A.; Tan, V. X. H.; Chan, L. T.; Frontini, M.; Wallace, C.; Malysheva, V.; Bottolo, L.; Vigorito, E.; Spivakov, M.
10.1101/2023.08.04.551251 — genetics — Posted on 2023-08-15
2502 Structure and function of the human mitochondrial MRS2 channel
He, Z.; Tu, Y.-C.; Tsai, C.-W.; Mount, J.; Zhang, J.; Tsai, M.-F.; Yuan, P.
10.1101/2023.08.12.553106 — biophysics — Posted on 2023-08-15
2503 Structural basis of allosteric modulation ofmetabotropic glutamate receptor activation and desensitization
Strauss, A.; Gonzalez-Hernandez, A. J.; Lee, J.; Abreu, N.; Selvakumar, P.; Salas-Estrada, L.; Kristt, M.; Marx, D.; Gilliland, K.; Melancon, B.; Filizola, M.; Meyerson, J.; Levitz, J.
10.1101/2023.08.13.552748 — biophysics — Posted on 2023-08-15
2505 Second Harmonic Generation Imaging Reveals Entanglement of Collagen Fibers in the Elephant Trunk Skin Dermis
Schulz, A.; Plotczyk, M.; Sordilla, S.; Boyle, M.; Singal, K.; Reidenberg, J.; Hu, D.; Higgins, C.
10.1101/2023.08.11.553031 — bioengineering — Posted on 2023-08-15
2507 Population interconnectivity shapes the distribution and complexity of chimpanzee cumulative culture
Gunasekaram, C.; Kuhlwilm, M.; Battiston, F.; Fontsere, C.; Padilla-Iglesias, C.; Kalan, A. K.; van Noordwiijk, M. A.; Manica, A.; Carvalho, S.; Bertranpetit, J.; Marques-Bonet, T.; Whiten, A.; van Schaik, C.; Vinicius, L.; Migliano, A. B.
10.1101/2023.08.14.553272 — evolutionary biology — Posted on 2023-08-15
2509 Single nucleotide polymorphisms and Zn transport by nuclear ZIP11 shape cancer phenotypes in HeLa cells
Kim, E. Y.; Verdejo-Torres, O.; Diaz-Rodriguez, K.; Hasanain, F.; Caromile, L. A.; PADILLA-BENAVIDES, T.
10.1101/2023.08.12.553076 — cell biology — Posted on 2023-08-15
2510 ATM-deficiency induced microglial activation promotes neurodegeneration in Ataxia-Telangiectasia
Lai, J.; Demirbas, D.; Kim, J.; Jeffries, A. M.; Tolles, A.; Park, J.; Chittenden, T. W.; Buckley, P. G.; Yu, T. W.; Lodato, M. A.; Lee, E. A.
10.1101/2021.09.09.459619 — neuroscience — Posted on 2023-08-15
2513 Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila
Anthoney, N.; Tainton-Heap, L.; Luong, H.; Notaras, E.; Kewin, A. B.; Zhao, Q.; Perry, T.; Batterham, P.; Shaw, P.; van Swinderen, B.
10.1101/2023.04.03.535331 — neuroscience — Posted on 2023-08-15
2516 The Influence of Leaf Anatomical Traits on Photosynthetic in Coffee Leaves
Xiao, Z.; Ma, G.; Bai, X.; Li, J.; Su, L.; Zhao, M.; Ma, H.; Zhou, H.
10.1101/2022.02.18.481015 — biophysics — Posted on 2023-08-15
2520 An actor-model framework for visual sensory encoding
Leong, F.; Rahmani, B.; Psaltis, D.; Moser, C.; Ghezzi, D.
10.1101/2023.08.14.553166 — bioengineering — Posted on 2023-08-15
2526 Protective concentric cardiac proteostasis adaptations to chronic cAMP-stress at young ages wanes in advanced age leading to accelerated cardiac aging
Perino, M. G.; Calvo-Rubio Barrera, M.; Agnetti, G.; Ranek, M.; Riordon, D.; Morrell, C.; Chakir, K.; Qu, J.; Tarasov, K.; Lakatta, E.
10.1101/2023.08.13.553128 — cell biology — Posted on 2023-08-14
2527 ATG2A-mediated bridge-like lipid transport regulates lipid droplet accumulation
Korfhage, J. L.; Wan, N.; Elhan, H.; Kauffman, L.; Pineda, M. J.; Fuller, D. M.; Thiam, A. R.; Reinisch, K.; Melia, T.
10.1101/2023.08.14.553257 — cell biology — Posted on 2023-08-14
2528 The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program
Burton, O.; Bricard, O.; Tareen, S.; Gergelits, V.; Andrews, S.; Roca, C. P.; Whyte, C.; Junius, S.; Brajic, A.; Pasciuto, E.; Ali, M.; Lemaitre, P.; Schlenner, S. M.; Ishigame, H.; Brown, B.; Dooley, J.; Liston, A.
10.1101/2023.08.14.553196 — immunology — Posted on 2023-08-14
2531 Neutron crystallographic refinement with REFMAC5 of the CCP4 suite
Catapano, L.; Long, F.; Yamashita, K.; Nicholls, R. A.; Steiner, R. A.; Murshudov, G. N.
10.1101/2023.08.13.552925 — bioinformatics — Posted on 2023-08-14
2532 SuperCellCyto: enabling efficient analysis of large scale cytometry datasets
Putri, G. H.; Howitt, G.; Marsh-Wakefield, F.; Ashhurst, T. M.; Phipson, B.
10.1101/2023.08.14.553168 — bioinformatics — Posted on 2023-08-14
2534 Relative importance of MCL-1's Anti-Apoptotic versus Non-Apoptotic Functions in vivo
Brinkmann, K.; McArthur, K.; Tee, A.; Kueh, A. J.; Malelang, S.; Wimmer, V.; Gibson, L.; Rowe, C. L.; Arandjelovic, P.; Dewson, G.; Putoczki, T.; Bouillet, P.; Fu, N.; Thomas, T.; Herold, M. J.; Voss, A. K.; Strasser, A.
10.1101/2023.08.14.553217 — cell biology — Posted on 2023-08-14
2535 A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
Guna, A.; Page, K. R.; Replogle, J. R.; Esantsi, T. K.; Wang, M. L.; Weissman, J. S.; Voorhees, R. M.
10.1101/2023.01.22.525086 — genomics — Posted on 2023-08-14
2536 GalNAc-siRNA Mediated Knockdown of Ketohexokinase Versus Systemic, Small Molecule Inhibition of its Kinase Activity Exert Divergent Effects on Hepatic Metabolism in Mice on a HFD
Softic, S.; Park, S.-H.; Fadhul, T.; Conroy, L. R.; Clarke, H.; Sun, R. C.; Wallenius, K.; Boucher, J.; O'Mahony, G.; Boianelli, A.; Persson, M.; Martinez, G. J.; Hinds, T. D.; Divanovic, S.
10.1101/2023.08.14.553218 — molecular biology — Posted on 2023-08-14
2537 XIST ribonucleoproteins promote female sex-biased autoimmunity
Dou, D. R.; Zhao, Y.; Belk, J. A.; Zhao, Y.; Casey, K. M.; Chen, D. C.; Li, R.; Yu, B.; Srinivasan, S.; Abe, B. T.; Kraft, K.; Hellstrom, C.; Sjoberg, R.; Chang, S. E.; Feng, A.; Goldman, D. W.; Shah, A. A.; Petri, M.; Chung, L. S.; Fiorentino, D. F.; Lundberg, E. K.; Wutz, A.; Utz, P. J.; Chang, H.
10.1101/2022.11.05.515306 — molecular biology — Posted on 2023-08-14
2538 NAD+ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages
Iske, J.; EL Fatimy, R.; Nian, Y.; Ghouzlani, A.; Eskandari, S.; Cetina Biefer, H. R.; Vasudevan, A.; Elkhal, A.
10.1101/2020.03.29.013649 — immunology — Posted on 2023-08-14
2539 Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis
Kelly, P.; McHugo, G. P.; Scaife, C.; Peters, S.; Stevenson, M. L.; McKay, J. S.; MacHugh, D. E.; Lara-Saez, I.; Breathnach, R.
10.1101/2023.08.11.552979 — immunology — Posted on 2023-08-14
2541 Gut mucosal cells transfer α-synuclein to the vagus nerve
Chandra, R.; Sokratian, A.; Chavez, K. R.; King, S.; Swain, S. M.; Snyder, J. C.; West, A. B.; Liddle, R. A.
10.1101/2023.08.14.553305 — neuroscience — Posted on 2023-08-14
2545 Stabilisation of the productive charge transfer states of coenzyme B12 in the photoreceptor protein, CarH
Camacho, I. S.; Wall, E.; Sazanovich, I. V.; Gozzard, E.; Towrie, M.; Hunt, N. T.; Hay, S.; Jones, A. R.
10.1101/2023.08.11.552799 — biophysics — Posted on 2023-08-14
2547 Variable Gain DNA Nanostructure Charge Amplifiers for Biosensing
Majikes, J. M.; Cho, S.; Cleveland, T. E.; Liddle, J. A.; Balijepalli, A.
10.1101/2023.08.11.552535 — bioengineering — Posted on 2023-08-14
2552 The Selenoproteome as a dynamic response mechanism to oxidative stress in methanogenic communities
Kleikamp, H. B. C.; Jaramillo, P. A. P.; Kofoed, M. V. W.; Papacharalampos, G.; Bentien, A.; Nielsen, J. L.
10.1101/2023.08.14.549203 — microbiology — Posted on 2023-08-14
2553 A vast repertoire of secondary metabolites influences community dynamics and biogeochemical processes in cold seeps
Dong, X.; Zhang, T.; Wu, W.; Peng, Y.; Liu, X.; Han, Y.; Chen, X.; Gao, Z.; Xia, J.; Shao, Z.; Greening, C.
10.1101/2023.08.12.552926 — microbiology — Posted on 2023-08-14
2554 Electrically controlled interaction between cable bacteria and carbon electrodes
Bonne, R.; Marshall, I. P. G.; Bjerg, J.; Marzocchi, U.; Manca, J.; Nielsen, L. P.; Aiyer, K.
10.1101/2023.08.14.553267 — microbiology — Posted on 2023-08-14
2555 Ikzf1 association with Foxp3 for Foxp3-dependent gene repression in Treg cells: induction of autoimmunity and tumor immunity by disrupting the association
Ichiyama, K.; Long, J.; Kobayashi, Y.; Horita, Y.; Kinoshita, T.; Nakamura, Y.; Kominami, C.; Georgopoulos, K.; Sakaguchi, S.
10.1101/2023.08.12.553084 — immunology — Posted on 2023-08-14
2559 DARTsort: A modular drift tracking spike sorter for high-density multi-electrode probes
Boussard, J.; Windolf, C.; Hurwitz, C.; Lee, H. D.; Yu, H.; Winter, O.; Paninski, L.
10.1101/2023.08.11.553023 — neuroscience — Posted on 2023-08-14
2563 Intern-based thermoregulated meganucleases for biocontainment of genetic material
Foo, G. W.; Leichthammer, C. D.; Saita, I. M.; Lukas, N. D.; Batko, I. Z.; Heinrichs, D. E.; Edgell, D.
10.1101/2023.08.14.553307 — synthetic biology — Posted on 2023-08-14
2565 Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong, L.; Braden, d. C.; Zhao, Y.; Skoko, J. J.; Chang, F.; Woodcock, S. R.; Uvale, C.; Casey, A.; Wood, K.; Salavatore, S.; Alp, A.; Harkness, T.; Fagunloye, A.; Razzaghi, M.; Straub, A. C.; Spies, M.; Brown, D. D.; LEE, A. V.; Schopfer, F. J.; Freeman, B. A.; Carola, C. A.
10.1101/2023.08.11.552990 — pharmacology and toxicology — Posted on 2023-08-14
2566 Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression
Gamage, H. E. V.; Shahoei, S. H.; Albright, S. T.; Wang, Y.; Smith, A. J.; Farmer, R.; Fink, E. C.; Jacquin, E.; Weisser, E.; Bautista, R. O.; Henn, M. A.; Schane, C. P.; Nelczyk, A. T.; Ma, L.; Das Gupta, A.; Bendre, S. V.; Nguyen, T.; Tiwari, S.; Krawczynska, N.; He, S.; Tjoanda, E.; Chen, H.; Sverdlov, M.; Gann, P. H.; Boidot, R.; Vegran, F.; Fanning, S. W.; Apetoh, L.; Hergenrother, P. J.; Nelson, E. R.
10.1101/2023.08.14.553229 — cancer biology — Posted on 2023-08-14
2570 Crowdsourcing and phylogenetic modelling reveal parrot tool use is not rare
Bastos, A. P.; Claessens, S.; Nelson, X. J.; Welch, D.; Atkinson, Q. D.; Taylor, A. H.
10.1101/2023.08.14.553302 — animal behavior and cognition — Posted on 2023-08-14
2574 MYC and MAX drive the reactivation of the genome after mitosis
Gonzalez, I.; Chervova, A.; Escoll Guerrero, P.; Altamirano-Pacheco, L.; Mueller, F.; Dubois, A.; Navarro, P.
10.1101/2023.08.13.553120 — molecular biology — Posted on 2023-08-14
2577 SAMD1 suppresses epithelial-mesenchymal transition (EMT) pathways in pancreatic ductal adenocarcinoma
Simon, C.; Brunke, I. D.; Stielow, B.; Forne, I.; Steitz, A. M.; Geller, M.; Rohner, I.; Jeude, L. M.; Weber, L. M.; Fischer, S.; Nist, A.; Stiewe, T.; Huber, M.; Buchholz, M.; Liefke, R.
10.1101/2023.08.14.553183 — molecular biology — Posted on 2023-08-14
2578 Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow
Huang, T.; Lu, Z.; Wang, Z.; Cheng, L.; Gao, L.; Gao, J.; Zhang, N.; Geng, C.-A.; Zhao, X.; Wang, H.; Wong, C.-W.; Yeung, K. W. K.; Pan, H.; Lu, W. W.; Guan, M.
10.1101/2023.08.14.552932 — molecular biology — Posted on 2023-08-14
2579 Bacterial degradation of ctenophore Mnemiopsis leidyi organic matter
Fadeev, E.; Hennenfeind, J. H.; Amano-Sato, C.; Zhao, Z.; Klun, K.; Herndl, G. J.; Tinta, T.
10.1101/2023.08.14.553244 — microbiology — Posted on 2023-08-14
2580 Cigarette smoking promotes the spread of antimicrobial resistance in the human lung and the environment
Fang, P.; Konyali, D.; Fischer, E.; Mayer, R. P.; Huang, J.; Elena, A. X.; Orzechowski, G. H.; Tony-Odigie, A.; Kneis, D.; Dalpke, A. H.; Krebs, P.; Li, B.; Berendonk, T. U.; Klümper, U.
10.1101/2023.08.14.553211 — microbiology — Posted on 2023-08-14
2583 Goblet cell invasion promotes breaching of respiratory epithelia by an opportunistic human pathogen
Swart, A. L.; Laventie, B. J.; Suetterlin, R.; Junne, T.; Yu, X.; Karagkiozi, E.; Okujava, R.; Jenal, U.
10.1101/2023.08.13.553119 — microbiology — Posted on 2023-08-14
2584 Mucus physically restricts influenza A viral particle access to the epithelium
Kaler, L.; Engle, E. M.; Iverson, E.; Boboltz, A.; Ignacio, M. A.; Rife, M.; Scull, M. A.; Duncan, G.
10.1101/2023.08.14.553271 — microbiology — Posted on 2023-08-14
2585 Combination Treatment to Improve Mucociliary Transport of Pseudomonas aeruginosa Biofilms
Rouillard, K. R.; Esther, C. P.; Kissner, W.; Plott, L. M.; Bowman, D. W.; Markovetz, M. R.; Hill, D. B.
10.1101/2023.08.14.553173 — microbiology — Posted on 2023-08-14
2587 Linking spontaneous and stimulated spine dynamics
Eggl, M.; Chater, T.; Petkovic, J.; Goda, Y.; Tchumatchenko, T.
10.1101/2023.08.11.552933 — neuroscience — Posted on 2023-08-14
2588 Neural Domains Associated with Substance Use Disorders: A Systematic Review of Neuroimaging Studies
Hinojosa, C. A.; Sitar, S. I.; Zhao, J. C.; Barbosa, J. D.; Hien, D. A.; Welsh, J. W.; Fani, N.; van Rooij, S. J. H.
10.1101/2023.08.11.552870 — neuroscience — Posted on 2023-08-14
2592 Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe
Ouasti, F.; Audin, M.; Freon, K.; Quivy, J.-P.; Tachekort, M.; Cesard, E.; Thureau, A.; Ropars, V.; Varela, P. F.; Moal, G.; Soumana-Amadou, I.; Uryga, A.; Legrand, P.; Andreani, J.; Guerois, R.; Almouzni, G.; Lambert, S. A.; Ochsenbein, F.
10.1101/2023.06.02.543505 — biochemistry — Posted on 2023-08-14
2594 Multi-omic stratification of the missense variant cysteinome
Desai, H. S.; Ofori, S.; Boatner, L. M.; Yu, F.; Villaneuva, M.; Ung, N.; Nesvizhskii, A.; Backus, K. M.
10.1101/2023.08.12.553095 — biochemistry — Posted on 2023-08-14
2595 A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in the human and mouse brains
Sziraki, A.; Lu, Z.; Lee, J.; Banyai, G.; Anderson, S.; Abdulraouf, A.; Metzner, E.; Liao, A.; Banfelder, J.; Epstein, A.; Schaefer, C.; Xu, Z.; Zhang, Z.; Gan, L.; Nelson, P. T.; Zhou, W.; Cao, J.
10.1101/2022.09.28.509825 — genomics — Posted on 2023-08-14
2599 Soft rot pathogen Dickeya dadantii 3937 produces tailocins resembling the tails of Enterobacteria bacteriophage P2
Borowicz, M.; Krzyzanowska, D. M.; Narajczyk, M.; Sobolewska, M.; Rajewska, M.; Czaplewska, P.; Wegrzyn, K.; Czajkowski, R.
10.1101/2023.08.14.553165 — microbiology — Posted on 2023-08-14
2604 SARS-CoV-2 Neutralizing Antibodies Following a Second BA.5 Bivalent Booster
Wang, Q.; Bowen, A.; Ho, J.; Zhang, R.; Valdez, R.; Stoneman, E.; Gordon, A.; Lihong, L.; Ho, D. D.
10.1101/2023.08.13.553148 — microbiology — Posted on 2023-08-14
2606 Phylogenomic analyses support a new infrageneric classification of Pourthiaea (Maleae, Rosaceae) using multiple inference methods and extensive taxon sampling
Liu, G.-N.; Ma, D.-K.; Zhang, Y.; Hodel, R. G. J.; Xie, S.-Y.; Wang, H.; Jin, Z.-T.; Li, F.-X.; Jin, S.-H.; Zhao, L.; Xu, C.; Wei, Y.; Liu, B.-B.
10.1101/2023.08.13.552906 — plant biology — Posted on 2023-08-14
2607 Photolipid excitation triggers depolarizing optocapacitive currents and action potentials
Bassetto, C. A. Z.; Pfeffermann, J.; Yadav, R.; Strassgschwandtner, S.; Glasnov, T.; Bezanilla, F.; Pohl, P.
10.1101/2023.08.11.552849 — biophysics — Posted on 2023-08-14
2611 A frog adaptive radiation: Ecomorphological evolution in Old-World shrub frogs (Rhacophoridae: Pseudophilautus)
Meegaskumbura, M.; Ellepola, G.; Senevirathne, G.; Manamendra-Arachchi, K.; Wijayathilaka, N.; Pie, M. R.; Sun, D.; Pethiyagoda, R.; Schneider, C. J.
10.1101/2023.08.12.549244 — evolutionary biology — Posted on 2023-08-14
2612 Impact of age and sex on neuroinflammation following SARS-CoV-2 infection in a murine model
D Krishna, V.; Chang, A.; Korthas, H.; Var, S. R.; Low, W. C.; Li, L.; Cheeran, M. C.-J.
10.1101/2023.08.11.552998 — microbiology — Posted on 2023-08-14
2613 Artemisitene protected against murine schistosomiasis japonica through anti-parasite activity and immune regulation
Liu, M.-k.; Chen, X.-y.; Tang, J.; Liu, Z.-p.; Lin, G.-y.; Cai, J.-l.; Chen, Z.-m.; Yan, Y.; ji, X.; Yang, Z.-j.; Li, Z.
10.1101/2023.08.11.552909 — immunology — Posted on 2023-08-14
2614 Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency
Millard, S. K.; Chiang, A. K.; Humburg, P.; Chowdhury, N.; Rehan, R.; Furman, A. J.; Mazaheri, A.; Schabrun, S. M.; Seminowicz, D. A.
10.1101/2023.08.11.552723 — neuroscience — Posted on 2023-08-14
2615 Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina
Wu, E. G.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Gogliettino, A. R.; Shah, N. P.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.
10.1101/2023.08.12.552902 — neuroscience — Posted on 2023-08-14
2616 Pantothenate Kinase 4 controls efficient skeletal muscle energy substrate metabolism via acetyl-CoA
Miranda-Cervantes, A.; Fritzen, A. M.; Raun, S. H.; Hodek, O.; Moller, L. L. V.; Johann, K.; Deisen, L.; Gregorevic, P.; Gudiksen, A.; Artati, A.; Adamski, J.; Andersen, N. R.; Schjerling, P.; Cebrian-Serrano, A.; Jaehnert, M.; Gottmann, P.; Burtscher, I.; Lickert, H.; Pilegaard, H.; Schuermann, A.; Tschoep, M. H.; Moritz, T.; Mueller, T. D.; Sylow, L.; Kiens, B.; Richter, E.; Kleinert, M.
10.1101/2023.08.14.551603 — physiology — Posted on 2023-08-14
2617 Identification of inter- and intra-tumoral molecular phenotypes steering temozolomide resistance in patient-derived glioblastoma cells.
Fabro, F.; Kers, T. V.; Feller, K. J.; Beerens, C.; Ntafoulis, I.; Idbaih, A.; Verrault, M.; Connor, K.; Biswas, A.; Salvucci, M.; Prehn, J. H. M.; Byrne, A. T.; O'Farrell, A. C.; Lambrechts, D.; Dilcan, G.; Lodi, F.; Arijs, I.; Kremer, A.; Tching Chi Yen, R.; Chien, M.-P.; Lamfers, M. L. M.; Leenstra, S.
10.1101/2023.08.11.552418 — cancer biology — Posted on 2023-08-14
2622 An ancestral dual function of OmpM as outer membrane tether and nutrient uptake channel in diderm Firmicutes
Silale, A.; Zhu, Y.; Witwinowski, J.; Smith, R. E.; Newman, K. E.; Bhamidimarri, S. P.; Basle, A.; Khalid, S.; BELOIN, C.; Gribaldo, S.; van den Berg, B.
10.1101/2023.08.14.552755 — biochemistry — Posted on 2023-08-14
2623 Fawn bedsite selection by a large ungulate living in a peri-urban area
Conteddu, K.; Wilson, K.; Amin, B.; Chari, S.; Haigh, A.; Griffin, L. L.; Quinn, M.; Ryan, A.; Smith, A. F.; Ciuti, S.
10.1101/2023.08.11.552922 — animal behavior and cognition — Posted on 2023-08-14
2626 GetPrimers: a generalized PCR-based genetic targeting primer designer enabling easy and standardized targeted gene modification across multiple systems
Miao, Z.; Wang, H.; Tu, X.; Huang, Z.; Huang, S.; Zhang, X.; Wang, F.; Huang, Z.; Li, H.; Jiao, Y.; Gao, S.; Zhou, Z.; Shan, C.-M.; Li, J.; Yue, J.-X.
10.1101/2023.08.12.552711 — genetics — Posted on 2023-08-14
2631 Does urbanization lead to parallel demographic shifts across the world in a cosmopolitan plant?
Caizergues, A. E.; Santangelo, J. S.; Ness, R. W.; Angeoletto, F.; Anstett, D. N.; Anstett, J.; Baena-Diaz, F.; Carlen, E. J.; Chaves, J. A.; Comerford, M. S.; Dyson, K.; Falahati-Anbaran, M.; Fellowes, M. D. E.; Hodgins, K. A.; Hood, G. R.; Iniguez-Armijos, C.; Kooyers, N. J.; Lazaro-Lobo, A.; Moles, A. T.; Munshi-South, J.; Paule, J.; Porth, I. M.; Santiago-Rosario, L. Y.; Stack Whitney, K.; Tack, A. J. M.; Johnson, M. T. J.
10.1101/2023.08.14.552623 — evolutionary biology — Posted on 2023-08-14
2632 Genetic and Geographic Patterns of Woody Plant Biosynthesis
Fahmi, M.; Takanashi, K.; Kakei, Y.; Kubota, Y.; Kanemoto, K.
10.1101/2023.08.12.553062 — ecology — Posted on 2023-08-14
2633 Deficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice
Norris, A. C.; Yazlovitskaya, E. M.; Zhu, L.; Rose, B. S.; Gibson-Corley, K. N.; May, J. C.; McLean, J. A.; Stafford, J. M.; Graham, T. R.
10.1101/2023.06.16.545392 — molecular biology — Posted on 2023-08-14
2635 Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors
Waibl Polania, J.; Hoyt-Miggelbrink, A. M.; Tomaszewski, W. H.; Wachsmuth, L. P.; Lorrey, S. J.; Wilkinson, D. S.; Lerner, E. C.; Woroniecka, K.; Finlay, J. B.; Fecci, P. E.
10.1101/2023.08.11.553007 — immunology — Posted on 2023-08-14
2636 Cryopreservation of cerebrospinal fluid cells preserves transcriptomics integrity for single-cell analysis
Kodali, M. C.; Antone, J.; Alsop, E.; Jayakuymar, R.; Parikh, K.; Sanchez-Molina, P.; Ajami, B.; Arnold, S. E.; Van Keuren-Jensen, K.; Das, S.; Weinberg, M. S.
10.1101/2023.08.10.552735 — neuroscience — Posted on 2023-08-14
2637 Mitochondrial complex I as a diagnostic and therapeutic target in a mouse model of tauopathy
Wong, J. H.; Vincent, A.; Khanapur, S.; Rong, T. J.; Ramasamy, B.; Hartimath, S.; Cheng, P.; Tsukada, H.; Robins, E. G.; Goggi, J. L.; Barron, A. M.
10.1101/2023.08.13.552232 — neuroscience — Posted on 2023-08-14
2639 Machine Learning-Driven Phenotype Predictions based on Genome Annotations
Edirisinghe, J. N.; Goyal, S.; Brace, A.; Colasanti, R.; Gu, T.; Sadhkin, B.; Zhang, Q.; Kamimura, R.; Henry, C. S.
10.1101/2023.08.11.552879 — systems biology — Posted on 2023-08-14
2640 Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring
Correa Pinto, D.; Canal Delgado, I.; Yang, H.; Clemenceau, A.; Corvelo, A.; Narzisi, G.; Musunuri, R.; Berger, J.; Hendricks, L.; Tokumura, K.; Luo, N.; Li, H.; Oury, F.; Ducy, P.; Yadav, V. K.; Li, X.; Karsenty, G.
10.1101/2023.08.11.552969 — physiology — Posted on 2023-08-14
2641 Age-linked lung pathology is reduced by immunotherapeutic targeting of isoDGR protein damage
Kalailingam, P.; Mohd-Kahliab, K.-H.; SoFong Cam Ngan, S. C. N.; Iyappan, R.; Lee, B. S. T.; Bhargy Sharma, B. S.; Machan, R.; Bo, S. T.; Chambers, E. S.; Fajardo, V. A.; Macpherson, R. E. K.; Liu, J.; Klentrou, P.; Tsiani, E. L.; Lim, K. L.; Su, I. H.; Gao, Y.-G.; Richard, A. M.; Kalaria, R. N.; Chen, C. P.; McCarthy, N. E.; Sze, S. K.
10.1101/2023.08.11.552994 — pathology — Posted on 2023-08-14
2644 NanoPyx: super-fast bioimage analysis powered by adaptive machine learning
Saraiva, B. M.; Cunha, I. M.; Brito, A. D.; Follain, G.; Portela, R.; Haase, R.; Pereira, P. M.; Jacquemet, G.; Henriques, R.
10.1101/2023.08.13.553080 — bioinformatics — Posted on 2023-08-14
2645 Accurate human genome analysis with Element Avidity sequencing
Carroll, A.; Kolesnikov, A.; Cook, D. E.; Brambrink, L.; Wiseman, K. N.; Billings, S. M.; Kruglyak, S.; Lajoie, B. R.; Zhao, J.; Levy, S. E.; McLean, C. Y.; Shafin, K.; Nattestad, M.; Chang, P.-C.
10.1101/2023.08.11.553043 — bioinformatics — Posted on 2023-08-14
2647 Structural elucidation and antiviral activity of cathepsin L inhibitors with carbonyl and epoxide warheads
Falke, S.; Lieske, J.; Herrmann, A.; Loboda, J.; Gunther, S.; Reinke, P. Y. A.; Ewert, W.; Karnicar, K.; Usenik, A.; Lindic, N.; Sekirnik, A.; Tsuge, H.; Turk, V.; Chapman, H. N.; Hinrichs, W.; Ebert, G.; Turk, D.; Meents, A.
10.1101/2023.08.11.552671 — biochemistry — Posted on 2023-08-14
2648 The spreading of facultative H3K9me3-heterochromatin drives congenital disease
Fang-Lin, S.; Chen, W.; Jian-Quan, N.; Wei, Z.; Xue-Lin, C.; Wen-Fei, W.; Yong-Hao, L.; Jian-Feng, C.; Xiao-Bo, G.; Yuan-Ya, J.; Ya-Bin, L.; Xin-YI, L.; Yu-Tong, L.; Kai, L.
10.1101/2023.08.11.552907 — genetics — Posted on 2023-08-14
2650 Specification and survival of post-metamorphic branchiomeric neurons in the hindbrain of a non-vertebrate chordate.
Gigante, E. D.; Piekarz, K. M.; Gurgis, A.; Cohen, L.; Razy-Krajka, F.; Popsuj, S.; Ali, H. S.; Mohana Sundaram, S.; Stolfi, A.
10.1101/2023.06.16.545305 — developmental biology — Posted on 2023-08-14
2651 Persistence of intact HIV-1 proviruses in the brain during antiretroviral therapy
Sun, W.; Rassadkina, Y.; Gao, C.; Collens, S. I.; Lian, X.; Solomon, I. H.; Mukerji, S. S.; Yu, X. G.; Lichterfeld, M.
10.1101/2023.06.26.546135 — microbiology — Posted on 2023-08-14
2654 Ascending vaginal infection in mice induces preterm birth and neonatal morbidity
Boyle, A. K.; Tetorou, K.; Suff, N.; Beecroft, L.; Mazzaschi, M.; Hristova, M.; Waddington, S. N.; Peebles, D.
10.1101/2023.08.14.553220 — neuroscience — Posted on 2023-08-14
2657 Marine heatwaves disrupt ecosystem structure and function via altered food webs and energy flux
Gomes, D. G. E.; Ruzicka, J. J.; Crozier, L. G.; Huff, D. D.; Brodeur, R. D.; Stewart, J. D.
10.1101/2023.08.11.553012 — systems biology — Posted on 2023-08-14
2658 ToxinPred 3.0: An improved method for predicting the toxicity of peptides
Rathore, A. S.; Arora, A.; Choudhury, S. P. S.; Tijare, P.; Raghava, G. P. S.
10.1101/2023.08.11.552911 — bioinformatics — Posted on 2023-08-14
2663 Coupled carbon and nitrogen cycling regulates the cnidarian-algal symbiosis
Radecker, N.; Escrig, S.; Spangenberg, J. E.; Voolstra, C. R.; Meibom, A.
10.1101/2022.12.06.519281 — ecology — Posted on 2023-08-14
2664 BBSome-deficient cells activate intraciliary CDC42 to trigger actin-dependent ciliary ectocytosis
Prasai, A.; Ivashchenko, O.; Maskova, K.; Cernohorska, M. S.; Stepanek, O.; Huranova, M.
10.1101/2023.08.13.553141 — cell biology — Posted on 2023-08-14
2666 Serpine1 negatively regulates Th1 cell responses in experimental autoimmune encephalomyelitis.
Akbar, I.; Tang, R.; Baillargeon, J.; Roy, A.-P.; Doss, P. M. I. A.; Zhu, C.; Kuchroo, V. K.; Rangachari, M.
10.1101/2023.07.13.548887 — immunology — Posted on 2023-08-14
2667 Mammalian olfactory cortex neurons retain molecular signatures of ancestral cell types
Zeppilli, S.; Gurrola, A. O.; Demetci, P.; Brann, D.; Attey, R.; Zilkha, N.; Kimchi, T.; Datta, S. R.; Singh, R.; Tosches, M. A.; Crombach, A.; Fleischmann, A.
10.1101/2023.08.13.553130 — neuroscience — Posted on 2023-08-14
2670 Cell-type-specific plasticity shapes neocortical dynamics for motor learning
Majumder, S.; Hirokawa, K.; Yang, Z.; Paletzki, R.; Gerfen, C. R.; Fontolan, L.; Romani, S.; Jain, A.; Yasuda, R.; Inagaki, H. K.
10.1101/2023.08.09.552699 — neuroscience — Posted on 2023-08-14
2672 Data-driven trait heritability-based extraction ofhuman facial phenotypes
Yuan, M.; Goovaerts, S.; Hoskens, H.; Richmond, S.; Walsh, S.; Shriver, M. D.; Shaffer, J. R.; Marazita, M. L.; Weinberg, S. M.; Peeters, H.; Claes, P.
10.1101/2023.08.13.553129 — bioinformatics — Posted on 2023-08-14
2674 Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids
Capauto, D.; Wang, Y.; Wu, F.; Norton, S.; Mariani, J.; Inoue, F.; Crawford, G. E.; Ahituv, N.; Abyzov, A.; Vaccarino, F. M.
10.1101/2023.08.14.553170 — genomics — Posted on 2023-08-14
2676 A developmental increase of inhibition promotes the emergence of hippocampal ripples
Pochinok, I.; Stöber, T. M.; Triesch, J.; Chini, M.; Hanganu-Opatz, I. L.
10.1101/2023.08.11.552951 — neuroscience — Posted on 2023-08-14
2679 Impaired extinction of cocaine seeking in HIV-infected mice is accompanied by peripheral and central immune dysregulation
Buck, L. A.; Xie, Q.; Willis, M.; Side, C. M.; Giacometti, L. L.; Gaskill, P. J.; Park, K.; Shaheen, F.; Guo, L.; Gorantla, S.; Barker, J. M.
10.1101/2023.08.11.552858 — neuroscience — Posted on 2023-08-14
2680 Video gaming, but not reliance on GPS, is associated with spatial navigation performance
Yavuz, E.; He, C.; Goodroe, S.; Gahnstrom, C.; Coutrot, A.; Hornberger, M.; Hegarty, M.; Spiers, H. J.
10.1101/2023.08.10.552365 — neuroscience — Posted on 2023-08-14
2695 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats
Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.
10.1101/2023.08.10.552777 — ecology — Posted on 2023-08-14
2696 Simulating animal space use from fitted integrated Step-Selection Functions (iSSF)
Signer, J.; Fieberg, J.; Reineking, B.; Schlaegel, U.; Smith, B. J.; Balkenhol, N.; Avgar, T.
10.1101/2023.08.10.552754 — ecology — Posted on 2023-08-14
2698 Colorful Lizards and the Conflict of Collection
Goodman, C.; Claunch, N.; Steele, Z.; Episcopio-Sturgeon, D.; Romagosa, C.
10.1101/2023.08.10.552819 — ecology — Posted on 2023-08-14
2700 A multi-channel TMS system enabling accurate stimulus orientation control during concurrent ultra-high-field MRI for preclinical applications
Souza, V. H.; Sinisalo, H.; Korhonen, J. T.; Paasonen, J.; Nyrhinen, M.; Nieminen, J. O.; Koponen, M. A.; Kettunen, M.; Grohn, O.; Ilmoniemi, R. J.
10.1101/2023.08.10.552401 — neuroscience — Posted on 2023-08-14
2701 Elevated serotonin in mouse spinal dorsal horn is pronociceptive
Cramer, N.; Ji, Y.; Kane, M. A.; Pilli, N.; Posa, L.; Van Patten, G.; Masri, R.; Keller, A.
10.1101/2023.08.10.552838 — neuroscience — Posted on 2023-08-14
2703 Studies on the International Space Station to assess the effects of microgravity on iPSC-derived neural organoids
Marotta, D.; Ijaz, L.; Barbar, L.; Nijsure, M.; Stein, J.; Clements, T.; Stoudemire, J.; Grisanti, P.; Noggle, S. A.; Loring, J. F.; Fossati, V.
10.1101/2023.08.10.552814 — neuroscience — Posted on 2023-08-14
2704 A convolutional neural network estimation of brain age is sensitive to cognitive impairment and decline
Yang, Y.; Sathe, A.; Schilling, K.; Shashikumar, N.; Moore, E.; Dumitrescu, L.; Pechman, K. R.; Landman, B. A.; Gifford, K. A.; Hohman, T. J.; Jefferson, A. L.; Archer, D. B.
10.1101/2023.08.10.552494 — neuroscience — Posted on 2023-08-14
2706 Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2
Spears, E.; Stanley, J. E.; Shou, M.; Dai, C.; Bradley, A.; Yin, L.; Li, X.; Sellick, K.; Poffenberger, G.; Coate, K. C.; Shrestha, S. D.; Jenkins, R.; Sloop, K.; Wilson, K. T.; Attie, A. D.; Keller, M. P.; Chen, W.; Powers, A. C.; Dean, E. D.
10.1101/2023.08.10.552656 — physiology — Posted on 2023-08-14
2707 Short-term fasting of a single amino acid extends lifespan.
Fulton, T. L.; Wansbrough, M. R.; Mirth, C. K.; Piper, M. D. W.
10.1101/2023.08.10.552880 — physiology — Posted on 2023-08-14
2708 L-Carnitine on contrast-induced nephropathy in diabetic rats
Oliveira, N. A.; Couto, S. M. F.; Borges, F. T.; Vattimo, M. d. F. F.; DA FONSECA, C. D.
10.1101/2023.08.10.552846 — pharmacology and toxicology — Posted on 2023-08-14
2709 Ovariectomy-Induced Arterial Stiffening Differs from Vascular Aging and is Reversed by GPER Activation
Kilanowski-Doroh, I.; McNally, A. B.; Wong, T. J.; Visniauskas, B.; Blessinger, S. A.; Imulinde Sugi, A.; Richard, C.; Diaz, Z.; Horton, A.; Natale, C. A.; Ogola, B. O.; Lindsey, S. H.
10.1101/2023.08.10.552881 — pharmacology and toxicology — Posted on 2023-08-14
2710 Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR
Herlinger, A. L.; Michaelsen, G. L.; Sinigaglia, M.; Fratini, L.; Debom, G. N.; Braganhol, E.; de Farias, C. B.; Brunetto, A. L.; Brunetto, A. T.; Jaeger, M. d. C.; Roesler, R.
10.1101/2023.08.10.552840 — cancer biology — Posted on 2023-08-14
2715 A new experimental evidence-weighted signaling pathway resource in FlyBase.
Attrill, H.; Antonazzo, G.; Goodman, J. L.; Thurmond, J.; Strelets, V. B.; Brown, N. H.
10.1101/2023.08.10.552786 — bioinformatics — Posted on 2023-08-14
2718 Network shape intelligence outperforms AlphaFold2 intelligence in vanilla protein interaction prediction.
Abdelhamid, I.; Muscoloni, A.; Rotscher, D. M.; Lieber, M.; Markwardt, U.; Cannistraci, C. V.
10.1101/2023.08.10.552825 — bioinformatics — Posted on 2023-08-14
2719 Bioluminescence Assay of Lysine Deacylase Sirtuin Activity
Van Scoyk, A. N.; Antelope, O.; Franzini, A.; Ayer, D. E.; Peterson, R. T.; Pomicter, A.; Owen, S. C.; Deininger, M. W.
10.1101/2023.08.10.552871 — bioengineering — Posted on 2023-08-14
2720 Comparative Analysis of Cameras and Software Tools for Skeleton Tracking
Aharony, N.; Meshurer, A.; Krakovski, M.; Parmet, Y.; Melzer, I.; Edan, Y.
10.1101/2023.08.10.552434 — bioengineering — Posted on 2023-08-14
2724 Persistence-colonization trade-off and niche differentiation enable the coexistence of E. coli phylogroups
Morel-Journel, T.; Lehtinen, S.; Cotto, O.; Martinson, J.; Clermont, O.; Walk, S.; Denamur, E.; Blanquart, F.
10.1101/2023.08.10.552787 — evolutionary biology — Posted on 2023-08-14
2727 Distribution and extent of suitable habitat for geladas (Theropithecus gelada) in the Anthropocene
AHMED, A. S.; Chala, D.; Kufa, C. A.; Atickem, A.; Simegn, A. B.; Svenning, J.-C.; Zinner, D.
10.1101/2023.08.10.552774 — ecology — Posted on 2023-08-14
2728 MICROGLIAL CELL EXPRESSION OF THE TYPE 2 CANNABINOID RECEPTOR REGULATES IMMUNE-MEDIATED NEUROINFLAMMATION
Moe, A.; Rayasam, A.; Sauber, G.; Shah, R.; Yuan, C. Y.; Szabo, A.; Moore, B.; Colonna, M.; Cui, W.; Romero, J.; Zamora, A.; Hillard, C.; Drobyski, W.
10.1101/2023.08.10.552854 — immunology — Posted on 2023-08-14
2729 Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers
Dean, I. W.; Lee, C. Y.; Tuong, Z. K.; Li, Z.; Tibbitt, C. A.; Willis, C.; Gaspal, F.; Kennedy, B. C.; Matei-Rascu, V.; Fiancette, R.; Nordenvall, C.; Lindforss, U.; Baker, S. M.; Stockmann, C.; Sexl, V.; Carlesso, G.; Hammond, S. A.; Dovedi, S.; Mjosberg, J.; Hepworth, M. R.; Clatworthy, M. R.; Withers, D. R.
10.1101/2023.08.10.552797 — immunology — Posted on 2023-08-14
2731 Cryopreservation of cerebrospinal fluid cells preserves transcriptomics integrity for single-cell analysis
Kodali, M. C.; Antone, J.; Alsop, E.; Jayakuymar, R.; Parikh, K.; Sanchez-Molina, P.; Ajami, B.; Arnold, S. E.; Van Keuren-Jensen, K.; Das, S.; Weinberg, M. S.
10.1101/2023.08.10.552735 — neuroscience — Posted on 2023-08-14
2732 Meningeal CSF transport is primarily mediated by the arachnoid and pia maters during development
Pan, S.; Koleske, J.; Koller, G. M.; Halupnik, G. L.; Alli, A.-H. O.; Koneru, S.; DeFreitas, D.; Ramagiri, S.; Strahle, J. M.
10.1101/2023.08.10.552826 — neuroscience — Posted on 2023-08-14
2733 Sex differences in seizure presentation in Dravet syndrome model mice, Scn1a+/-
Vermudez, S. A. D.; Lin, R.; McGinty, G.; Liebhardt, A.; Choe, Y.; Hui, B.; Lubbers, E.; Dhamne, S. C.; Hameed, M. Q.; Rotenberg, A.
10.1101/2023.08.10.552872 — neuroscience — Posted on 2023-08-14
2735 Chemotherapeutic regulation of the ROS/MondoA-dependent TXNIP/GDF15 axis; and derivation of a new organoid metric as a predictive biomarker
Deng, J.; Pan, T.; Hong, Y.; Liu, Z.; Zhou, X.; An, Z.; Li, L.; Alfano, G.; Li, G.; Dolcetti, L.; Evans, R.; Vicencio, J. M.; Vlckova, P.; Chen, Y.; Monypenny, J.; Gomes, C.; Ng, K.; McCarthy, C.; Yang, X.; Hu, Z.; Porter, J. C.; Tape, C.; Yin, M.; Rodriguez-Justo, M.; Tejpar, S.; Beatson, R.; Ng, T.
10.1101/2023.08.10.552749 — cancer biology — Posted on 2023-08-14
2736 Exploiting Epigenetic Targets to Overcome Taxane Resistance in Prostate Cancer
Cevatemre, B.; Bulut, I.; Dedeoglu, B.; Isiklar, A.; Syed, H.; Yedier Bayram, O.; Bagci-Onder, T.; Acilan Ayhan, C.
10.1101/2023.08.10.552560 — cancer biology — Posted on 2023-08-14
2738 weIMPUTE: A User-Friendly Web-Based Genotype Imputation Platform
Tang, Y.; Li, M. L.; Li, Z.; Li, Q.; Hu, X. D.; Yu, J.; Lin, J.; Bi, C. G.; Yu, H. L.; Huang, M.
10.1101/2023.08.10.552759 — bioinformatics — Posted on 2023-08-14
2739 Single-cell profiling uncovers regulatory programs of pathogenic Th2 cells in allergic asthma
Khan, M.; Alteneder, M.; Reiter, W.; Krausgruber, T.; Dobnikar, L.; Madern, M.; Waldherr, M.; Bock, C.; Hartl, M.; Ellmeier, W.; Henriksson, J.; Boucheron, N.
10.1101/2023.08.10.552772 — immunology — Posted on 2023-08-14
2740 TMS provokes target-dependent intracranial rhythms across human cortical and subcortical sites
Solomon, E. A.; Wang, J. B.; Oya, H.; Howard, M. A.; Trapp, N. T.; Uitermarkt, B. D.; Boes, A. D.; Keller, C. J.
10.1101/2023.08.09.552524 — neuroscience — Posted on 2023-08-14
2741 Expansion of a frontostriatal salience network in individuals with depression
Lynch, C. J.; Elbau, I.; Ng, T.; Ayaz, A.; Zhu, S.; Manfredi, N.; Johnson, M.; Wolk, D.; Power, J. D.; Gordon, E. M.; Kay, K.; Aloysi, A.; Moia, S.; Gaudes, C. C.; Victoria, L. W.; Solomonov, N.; Goldwaser, E.; Zebley, B.; Grosenick, L.; Downar, J.; Vila-Rodriguez, F.; Daskalakis, Z. J.; Blumberger, D. M.; Williams, N.; Gunning, F.; Liston, C.
10.1101/2023.08.09.551651 — neuroscience — Posted on 2023-08-14
2744 Vitamin D deficiency induces erectile dysfunction: role of superoxide
Olivencia, M. A.; Climent, B.; Barreira, B.; Morales-Cano, D.; Sanchez, A.; Fernandez, A.; Garcia-Gomez, B.; Romero-Otero, J.; Rodriguez, C.; Moreno, L.; Prieto, D.; Larriba, M. J.; Cogolludo, A.; Angulo, J.; Perez-Vizcaino, F.
10.1101/2023.08.09.552595 — pharmacology and toxicology — Posted on 2023-08-14
2749 Complete Suspension Differentiation of Human Pluripotent Stem Cells into Pancreatic Islets Using Vertical-Wheel Bioreactors
Dadheech, N.; Bermudez de Leon, M.; Cuesta-Gomez, N.; Jasra, I. T.; Pawlick, R.; Marfil-Garza, B.; Verhoeff, K.; Sapkota, S.; Razavy, H.; Anwar, P.; Lyon, J.; Macdonald, P. E.; O' Gorman, D.; Jickling, G.; Shapiro, A. J.
10.1101/2023.08.09.552676 — bioengineering — Posted on 2023-08-14
2752 Dabrafenib alters MDSC differentiation and function by activation of GCN2
Ciudad, M. T.; Quevedo, R.; Lamorte, S.; Jin, R.; Nzirorera, N.; Koritzinsky, M.; McGaha, T. L.
10.1101/2023.08.09.552588 — immunology — Posted on 2023-08-14
2753 Napping and circadian sleep-wake regulation during healthy aging.
Deantoni, M.; Reyt, M.; Baillet, M.; Dourte, M.; de Haan, S.; Lesoinne, A.; Vandewalle, G.; Maquet, P.; Berthomier, C.; Muto, V.; Hammad, G.; Schmidt, C.
10.1101/2023.08.09.552270 — neuroscience — Posted on 2023-08-14
2759 A mean-field theory for predicting single polymer collapse induced by neutral crowders
Chaboche, Q.; Campos-Villalobos, G.; Giunta, G.; Dijkstra, M.; Cosentino Lagomarsino, M.; Scolari, V. F.
10.1101/2023.07.12.548683 — biophysics — Posted on 2023-08-14
2761 Profiling novel lateral gene transfer events in the human microbiome
Hsu, T. Y.; Nzabarushimana, E.; Wong, D.; Luo, C.; Beiko, R. G.; Langille, M.; Huttenhower, C.; Nguyen, L. H.; Franzosa, E. A.
10.1101/2023.08.08.552500 — bioinformatics — Posted on 2023-08-14
2768 Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
Bilgic, M.; Wu, Q.; Suetsugu, T.; Tsunekawa, Y.; Shitamukai, A.; Kadota, M.; Nishimura, O.; Kuraku, S.; Shimogori, T.; Kiyonari, H.; Matsuzaki, F.
10.1101/2022.05.05.490846 — developmental biology — Posted on 2023-08-14
2769 Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia
Monzel, M.; Leelaarporn, P.; Lutz, T.; Schultz, J.; Brunheim, S.; Reuter, M.; McCormick, C.
10.1101/2023.08.11.552915 — neuroscience — Posted on 2023-08-13
2773 Portable X-ray Fluorescence for Measuring Lead in the Hair of Wild Mammals
Jones, E. M.; Bengsen, A. J.; Specht, A. J.; Koch, A. J.; Hamede, R. K.; Jones, M. E.; Hampton, J. O.
10.1101/2023.03.13.531209 — ecology — Posted on 2023-08-13
2775 Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis
Xie, O.; Morris, J. M.; Hayes, A. J.; Towers, R. J.; Jespersen, M. G.; Lees, J. A.; Ben Zakour, N. L.; Berking, O.; Baines, S. L.; Carter, G. P.; Tonkin-Hill, G.; Schrieber, L.; McIntyre, L.; Lacey, J. L.; James, T. B.; Sriprakash, K. S.; Beatson, S. A.; Hasegawa, T.; Giffard, P.; Steer, A. C.; Batzloff, M. R.; Beall, B. W.; Pinho, M. D.; Ramirez, M.; Bessen, D. E.; Dougan, G.; Bentley, S. D.; Walker, M. J.; Currie, B. J.; Tong, S. Y.; McMillan, D. J.; Davies, M. R.
10.1101/2023.08.10.552873 — microbiology — Posted on 2023-08-13
2776 Brain Specific Estrogen Ameliorates Cognitive Effects of Surgical Menopause in Mice
Salinero, A. E.; Abi-Ghanem, C.; Venkataganesh, H.; Sura, A.; Smith, R. M.; Thrasher, C. A.; Kelly, R. D.; Hatcher, K. M.; Nyblom, V.; Shamlian, V.; Kyaw, N.-R.; Belanger, K. M.; Gannon, O. J.; Stephens, S. B.; Zuloaga, D. G.; Zuloaga, K. L.
10.1101/2023.08.09.552687 — neuroscience — Posted on 2023-08-13
2778 Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism
Bridi, M.; Luo, N.; Kim, G.; O'Ferrall, C.; Oatel, R.; Bertrand, S.; Kannan, S.; Kirkwood, A.
10.1101/2021.07.05.451213 — neuroscience — Posted on 2023-08-13
2780 Shifting KRAS hotspot mutations inhibition paradigm in colorectal cancer
Bras, A. R.; Lopes, A.; Mendes, N.; Costa, P. J.; Ferreira, A.; Granja, S.; Silva, A. P.; Tortosa, F.; Baltazar, F.; Gartner, F.; Sousa, M. J.; Valente, A.; Preto, A.
10.1101/2023.08.09.552513 — pharmacology and toxicology — Posted on 2023-08-13
2781 Role of Adenosine Deaminase in Prostate Cancer Progression
Charles, C.; Lloyd, S. M.; Piyarathna, D. W. B.; Gohlke, J.; Rasaily, U.; Putluri, V.; Simons, B. W.; Zaslavsky, A.; Nallandhighal, S.; Palanisamy, N.; Navone, N.; Jones, J. A.; Ittmann, M. M.; Putluri, N.; Rowley, D. R.; Salami, S. S.; Palapattu, G.; Sreekumar, A.
10.1101/2023.08.09.552704 — cancer biology — Posted on 2023-08-13
2782 Single-cell transcriptional profiling of clear cell renal cell carcinoma reveals an invasive tumor vasculature phenotype
Zvirblyte, J.; Nainys, J.; Juzenas, S.; Kubiliute, R.; Kincius, M.; Ulys, A.; Jarmalaite, S.; Mazutis, L.
10.1101/2023.08.09.552568 — cancer biology — Posted on 2023-08-13
2783 Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy
Wang, L.; Xiao, Y.; Luo, Y.; Master, R. P.; Mo, J.; Kim, M.-C.; Liu, Y.; Patel, U. M.; Li, X.; Shaffer, D.; Guertin, K. R.; Moser, E.; Smalley, K.; Zhou, D.; Zheng, G.; Zhang, W.
10.1101/2023.08.09.552650 — cancer biology — Posted on 2023-08-13
2784 Multiplexed Digital Characterisation of Misfolded Protein Oligomers via Solid-State Nanopores
Sandler, S. E.; Horne, R. I.; Rocchetti, S.; Novak, R.; Hsu, N.-S.; Cruz, M. C.; Brotzakis, Z. F.; Gregory, R. C.; Chia, S.; Bernardes, G. J. L.; Keyser, U. F.; Vendruscolo, M.
10.1101/2023.08.09.552642 — biophysics — Posted on 2023-08-13
2787 YiNet: An Integrated Traditional Chinese and Western Medicine Platform for Viral Infectious Diseases
Dong, F.; Guo, J.; Liu, L.; Han, A.; Zhang, J.; He, Z.; Qu, X.; Lei, S.; Wang, Z.; Zhou, L.; Wang, Y.; He, H.; Bu, D.; Zhao, Y.; Gu, X.
10.1101/2023.08.09.552248 — bioinformatics — Posted on 2023-08-13
2789 Blood-based Nano-QuIC: Accelerated and Inhibitor-resistant Detection of Misfolded Alpha-synuclein
Christenson, P. R.; Jeong, H.; Li, M.; Ahn, H.; Li, D.; Larsen, P. A.; Park, H. Y.; Oh, S.-H.
10.1101/2023.08.09.552630 — bioengineering — Posted on 2023-08-13
2790 Improved chromosome-level genome assembly for marigold (Tagetes erecta)
Jiang, F.; Yuan, L.; Wang, S.; Wang, H.; Xu, D.; Wang, A.; Fan, W.
10.1101/2023.07.25.550479 — genomics — Posted on 2023-08-13
2792 Environment predicts the maintenance of reproductive isolation in a mosaic hybrid zone of rubber rabbitbrush
Faske, T. M.; Agneray, A. C.; Jahner, J. P.; Osuna-Mascaro, C.; Sheta, L. M.; Richardson, B. A.; Leger, E. A.; Parchman, T. L.
10.1101/2023.08.09.552705 — evolutionary biology — Posted on 2023-08-13
2794 From microbial communities to regional biogeography: Unraveling patterns, determinants and the influence of bottom trawling in benthic microbiota
Bonthond, G.; Beermann, J.; Gutow, L.; Neumann, A.; Barboza, F. R.; Desiderato, A.; Fofonova, V.; Helber, S.; Khodami, S.; Kraan, C.; Neumann, H.; Rohde, S.; Schupp, P. J.
10.1101/2023.08.09.552457 — ecology — Posted on 2023-08-13
2795 Diverse Epithelial Lymphocytes in Zebrafish Revealed Using a Novel Scale Biopsy Method
Park, G.; Foster, C. A.; Malone-Perez, M.; Hasan, A.; Macias, J. J.; Frazer, J. K.
10.1101/2023.08.09.552511 — immunology — Posted on 2023-08-13
2796 Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson's disease revealed by in vivo PET imaging
Delgado-Goni, T.; Connor-Robson, N.; Cioroch, M.; Paisey, S.; Marshall, C.; Lane, E. L.; Hauton, D.; McCullagh, J.; Magill, P. J.; Cragg, S. J.; Mackay, C. E.; Wade-Martins, R.; Klein, J. C.
10.1101/2023.08.09.550512 — neuroscience — Posted on 2023-08-13
2797 Small fibre neuropathy in Fabry disease: a human-derived neuronal in vitro disease model
Klein, T.; Gruener, J.; Breyer, M.; Schlegel, J.; Schottmann, N. M.; Hofmann, L.; Gauss, K.; Mease, R.; Erbacher, C.; Finke, L.; Klein, A.; Klug, K.; Karl-Schoeller, F.; Vignolo, B.; Reinhard, S.; Schneider, T.; Guenther, K.; Fink, J.; Dudek, J.; Maack, C.; Klopocki, E.; Seibel, J.; Edenhofer, F.; Wischmeyer, E.; Sauer, M.; Uceyler, N.
10.1101/2023.08.09.552621 — neuroscience — Posted on 2023-08-13
2798 Actomyosin-II Proactively Shields Axons of the Central Nervous System from Mild Mechanical Stress
Pan, X.; Lei, G.; Li, J.; Luan, T.; Hu, Y.; Chu, Y.; Feng, Y.; Zhan, W.; Zhao, C.-x.; Meunier, F. A.; Liu, Y.; LI, Y.; Wang, T.
10.1101/2023.08.09.552549 — neuroscience — Posted on 2023-08-13
2801 Design of a Biohybrid Materials Circuit with Binary Decoder Functionality
Mohsenin, H.; Wagner, H.; Rosenblatt, M.; Kemmer, S.; Timmer, J.; Weber, W.
10.1101/2023.08.10.552766 — synthetic biology — Posted on 2023-08-13
2803 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E.; Baker, T. M.; Lesluyes, T.; Monlong, J.; Abe, K. T.; Coelho, P. P.; Schwartz, M.; Zou, D.; Morin, G.; Pacis, A.; Yang, Y.; Martinez, C.; Barber, J.; Kuasne, H.; Li, R.; Bourgey, M.; Fortier, A.-M.; Davison, P. G.; Omeroglu, A.; Guiot, M. C.; Morris, Q.; Kleinman, C. L.; Huang, S.; Gingras, A.-C.; Ragoussis, I.; Bourque, G.; Van Loo, P.; Park, M.
10.1101/2023.06.10.544434 — genomics — Posted on 2023-08-13
2804 Three Accessory Gene Clusters Drive Host-Adaptation in Group B Streptococcus
Crestani, C.; Forde, T. L.; Bell, J.; Lycett, S. J.; Oliveira, L. M.; Pinto, T. C.; Cobo-Angel, C. G.; Ceballos-Marquez, A.; Phuoc, N. N.; Sirimanapong, W.; Chen, S. L.; Jamrozy, D.; Bentley, S. D.; Fontaine, M.; Zadoks, R. N.
10.1101/2023.08.10.552778 — genomics — Posted on 2023-08-13
2805 Comprehensive analyses of 1771 transcriptome from seven tissues enhance genetic and biological interpretations of maize complex traits
Lei, M.; Si, H.; Zhu, M.; Han, Y.; Liu, W.; Dai, Y.; Ji, Y.; Liu, Z.; Hao, F.; Hao, R.; Zhao, J.; Ye, G.; Zan, Y.
10.1101/2023.08.09.552713 — genetics — Posted on 2023-08-13
2806 Genetic and karyotype divergence between parents affect clonality and sterility in hybrids
Marta, A.; Tichopad, T.; Bartos, O.; Klima, J.; shah, M.; Bohlen, V. S.; Bohlen, J.; Halacka, K.; Choleva, L.; Stöck, M.; Dedukh, D.; Janko, K.
10.1101/2023.04.11.536494 — evolutionary biology — Posted on 2023-08-13
2809 Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development
Shafaattalab, S.; LI, A. Y.; Maaref, Y.; Jayousi, F.; Dababneh, S.; Hamledari, H.; Baygi, D. H.; Barszczewski, T.; Rupai, B.; Jannati, S.; Nagalingam, R.; Cool, A. M.; Langa, P.; Chiao, M.; Roston, T.; Solaro, R. J.; Sanatani, S.; Toepfer, C.; Lindert, S.; Lange, P. F.; Tibbits, G. F.
10.1101/2023.06.06.542948 — cell biology — Posted on 2023-08-13
2810 ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes
Bunch, H.; Kim, D.; Naganuma, M.; Nakagawa, R.; Cong, A.; Jeong, J.; Ehara, H.; Vu, H.; Chang, J. H.; Schellenberg, M.; Sekine, S.-i.
10.1101/2022.08.09.503353 — molecular biology — Posted on 2023-08-13
2813 Comodulation reduces interindividual variability of circuit output
Schneider, A. C.; Itani, O.; Cronin, E.; Daur, N.; Bucher, D.; Nadim, F.
10.1101/2023.06.03.543573 — neuroscience — Posted on 2023-08-13
2814 Overexpression of tomato SlBBX16 and SlBBX17 impacts fruit development and GA biosynthesis
Dusi, V.; Pennisi, F.; Fortini, D.; Atares, A.; Wenkel, S.; Molesini, B.; Pandolfini, T.
10.1101/2023.08.12.553068 — plant biology — Posted on 2023-08-13
2818 Synergistic control of chloroplast biogenesis by MYB-related and Golden2-like transcription factors
Frangedakis, E.; Yelina, N.; Billakurthi, K.; Schreier, T. B.; Dickinson, P. J.; Tomaselli, M.; Haseloff, J.; Hibberd, J. M.
10.1101/2023.08.11.552970 — plant biology — Posted on 2023-08-13
2819 Non-Stationary Dynamic Mode Decomposition
Ferre, J.; Rokem, A.; Buffalo, E. A.; Kutz, J. N.; Fairhall, A.
10.1101/2023.08.08.552333 — neuroscience — Posted on 2023-08-13
2822 Early Deprivation Impairs Perforant Pathway Connectivity and Contextual Memory in Adolescent Male Mice
Islam, R.; White, J. D.; Arefin, T. M.; Mehta, S.; Liu, X.; Polis, B.; Giuliano, L.; Ahmed, S.; Bowers, C.; Zhang, J.; Kaffman, A.
10.1101/2023.08.08.552517 — neuroscience — Posted on 2023-08-13
2829 Ton Motor Conformational Switch and Peptidoglycan Role in Bacterial Nutrient Uptake
Zinke, M.; Lejeune, M.; Mechaly, A.; Bardiaux, B.; Boneca, I.; Delepelaire, P.; Izadi-Pruneyre, N.
10.1101/2023.08.11.552980 — microbiology — Posted on 2023-08-13
2835 Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions
Kar, M.; Vogel, L. T.; Chauhan, G.; Ausserwoger, H.; Welsh, T. J.; Kamath, A. R.; Knowles, T. P. J.; Hyman, A. A.; Seidel, C. A. M.; Pappu, R. V.
10.1101/2023.08.11.552963 — biophysics — Posted on 2023-08-13
2838 Transferrin Receptor Targeting Chimeras (TransTACs) for Membrane Protein Degradation
Zhang, D.; Duque-Jimenez, J.; Brixi, G.; Facchinetti, F.; Rhee, K.; Feng, W. W.; Jänne, P. A.; Zhou, X.
10.1101/2023.08.10.552782 — bioengineering — Posted on 2023-08-13
2840 Whole-Brain Causal Discovery Using fMRI
Arab, F.; Ghassami, A.; Jamalabadai, H.; Peters, M. A. K.; Nozari, E.
10.1101/2023.08.12.553067 — neuroscience — Posted on 2023-08-13
2841 PRDM16 co-operates with LHX2 to shape the human brain
Suresh, V.; Bhattacharya, B.; Tshuva, R. Y.; Danan Gotthold, M.; Olender, T.; Bose, M.; Ben Zeev, B.; Smith, R. S.; Pradhan, S. J.; Tole, S.; Galande, S.; Harwell, C.; Baizabal, M.; Reiner, O.
10.1101/2023.08.12.553065 — developmental biology — Posted on 2023-08-12
2842 BRAND: A platform for closed-loop experiments with deep network models
Ali, Y. H.; Bodkin, K.; Rigotti-Thompson, M.; Patel, K.; Card, N. S.; Bhaduri, B.; Nason-Tomaszewski, S. R.; Mifsud, D. M.; Hou, X.; Nicolas, C.; Allcroft, S.; Hochberg, L. R.; Yong, N. A.; Stavisky, S. D.; Miller, L. E.; Brandman, D. M.; Pandarinath, C.
10.1101/2023.08.08.552473 — neuroscience — Posted on 2023-08-12
2843 Stimulus invariant aspects of the retinal code drive discriminability of natural scenes
Hoshal, B.; Holmes, C. M.; Bojanek, K.; Salisbury, J. M.; Berry, M. J.; Marre, O.; Palmer, S.
10.1101/2023.08.08.552526 — neuroscience — Posted on 2023-08-12
2847 The entropy of resting-state neural dynamics is a marker of general cognitive ability in childhood
Zdorovtsova, N.; Young, E. J.; Akarca, D.; Anwyl-Irvine, A.; The RED Team, ; The CALM Team, ; Astle, D. E.
10.1101/2023.08.08.552448 — neuroscience — Posted on 2023-08-12
2848 The Dynamic Response of Human Lungs Due to Underwater Shock Wave Exposure
Bar-Kochba, E.; Iwaskiw, A. S.; Dunn, J. M.; Ott, K. A.; Harrigan, T. P.; Demetropoulos, C. K.
10.1101/2023.08.08.552452 — biophysics — Posted on 2023-08-12
2849 Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling
Nguyen, J.; Wang, L.; Lei, W.; Hu, Y.; Gulati, N.; Chavez-Madero, C.; Brandt, M.; Betz, T.; Gilbert, P. M.
10.1101/2023.08.08.552533 — bioengineering — Posted on 2023-08-12
2850 Land use change drives major loss of Southeast Asian biodiversity
Botterill-James, T.; Yates, L. A.; Buettel, J. C.; Aandahl, Z.; Brook, B. W.
10.1101/2023.08.08.552370 — ecology — Posted on 2023-08-12
2853 Implementation and testing of a biohybrid transitionmicroelectrode array for neural recording and modulation
Ahmed, B.; Binder, S.; Boroomand, S.; Strathman, H. J.; Hantak, M.; Shepherd, T.; Ehrenhofer, A.; Zhang, H.; Shepherd, J.; Solzbacher, F.; Tresco, P. A.; Blair, S.; Reiche, C. F.; Fan, Y.
10.1101/2023.08.08.552362 — neuroscience — Posted on 2023-08-12
2860 Tail length in male versus female fox squirrels (Sciurus niger)
Nichols, H. K.; Smith, S. K.; Eddington, V. M.; Calistri-Yeh, A.; Kloepper, L. N.; Young, V. K. H.
10.1101/2023.08.08.552536 — zoology — Posted on 2023-08-12
2862 An Unsupervised Contrastive Learning Model for Data Integration of Spatially Resolved Transcriptomics
Zhang, C.; Liu, L.; Zhang, Y.; Li, M.; Fang, S.; Kang, Q.; Chen, A.; Xu, X.; Zhang, Y.; Li, Y.
10.1101/2023.08.08.552402 — bioinformatics — Posted on 2023-08-12
2863 Profiling novel lateral gene transfer events in the human microbiome
Hsu, T. Y.; Nzabarushimana, E.; Wong, D.; Luo, C.; Beiko, R. G.; Langille, M.; Huttenhower, C.; Nguyen, L. H.; Franzosa, E. A.
10.1101/2023.08.08.552500 — bioinformatics — Posted on 2023-08-12
2866 Blocking oligomerization is the most viable strategy to inhibit STING
Chan, R. J. M.; Cao, X.; Ergun, S. L.; Njomen, E.; Lynch, S. R.; Cravatt, B. F.; Li, L.
10.1101/2023.08.11.553045 — biochemistry — Posted on 2023-08-12
2869 The defensome of complex bacterial communities
Beavogui, A.; Lacroix, A.; Wiart, N.; Poulain, J.; Delmont, T. O.; Paoli, L.; Wincker, P.; Oliveira, P. H.
10.1101/2023.08.12.553040 — genomics — Posted on 2023-08-12
2870 Comprehensive Assessment of the Intrinsic Pancreatic Microbiome
Eckhoff, A. M.; Fletcher, A. A.; Kelly, M. S.; Dohlman, A.; McIntyre, C. A.; Shen, X.; Iyer, M. K.; Nussbaum, D. P.; Allen, P. J.
10.1101/2023.08.12.553074 — microbiology — Posted on 2023-08-12
2877 Label-Free Composition Analysis of Supramolecular Polymer - Nanoparticle Hydrogels by Reversed-Phase Liquid Chromatography Coupled with a Charged Aerosol Detector
Tang, S.; Pederson, Z.; Meany, E. L.; Yen, C.-W.; Swansiger, A. K.; Prell, J. S.; Chen, B.; Grosskopf, A. K.; Eckman, N.; Jiang, G.; Baillet, J.; Pellett, J. D.; Appel, E. A.
10.1101/2023.08.11.553055 — biochemistry — Posted on 2023-08-12
2880 The aryl hydrocarbon receptor in beta-cells mediates the effects of TCDD on glucose homeostasis in mice
Hoyeck, M. P.; Ching, M. E. A.; Basu, L.; van Allen, K.; Palaniyandi, J.; Perera, I.; Poleo-Giorgani, E.; Hanson, A. A.; Bruin, J. E.
10.1101/2023.08.10.552760 — molecular biology — Posted on 2023-08-12
2881 Interkingdom interactions shape the fungal microbiome of mosquitoes
Hegde, S.; Khanipov, K.; Hornett, E. A.; Nilyanimit, P.; Pimenova, M.; Saldana, M. A.; Becker, C. d.; Golovko, G.; Hughes, G.
10.1101/2023.08.11.552965 — microbiology — Posted on 2023-08-12
2882 Toxinome - The Bacterial Protein Toxin Database
Danov, A.; Segev, O.; Bograd, A.; Ben Eliyahu, Y.; Dotan, N.; Kaplan, T.; Levy, A.
10.1101/2023.08.12.553073 — microbiology — Posted on 2023-08-12
2888 Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates
Yee, S. W.; Ferrandez-Peral, L.; Alentorn, P.; Fontsere, C.; Ceylan, M.; Koleske, M. L.; Handin, N.; Artegoitia, V. M.; Lara, G.; Chien, H.-C.; Zhou, X.; Dainat, J.; Zalevsky, A.; Sali, A.; Brand, C. M.; Capra, J. A.; Artursson, P.; Newman, J. W.; Marques-Bonet, T.; Giacomini, K. M.
10.1101/2023.08.08.552553 — pharmacology and toxicology — Posted on 2023-08-12
2890 Structural Remodeling of Fungal Cell Wall Promotes Resistance to Echinocandins
Dickwella Widanage, M. C.; Gautam, I.; Sarkar, D.; Mentink-Vigier, F.; Vermaas, J. V.; Fontaine, T.; Latge, J.-P.; Wang, P.; Wang, T.
10.1101/2023.08.09.552708 — biophysics — Posted on 2023-08-12
2894 A taxon-restricted duplicate of Iroquois3 is required for patterning the spider waist
Setton, E. V.; Ballesteros, J. A.; Blaszczyk, P. O.; Klementz, B. C.; Sharma, P. P.
10.1101/2023.08.08.552527 — evolutionary biology — Posted on 2023-08-12
2897 Assessing the global prevalence of wild birds in trade
Donald, P. F.; Fernando, E.; Brown, L.; Busana, M.; Butchart, S. H.; Chng, S.; de la Colina, A.; Machado Ferreira, J.; Jain, A.; Jones, V. R.; Lapido, R.; Malsch, K.; McDougall, A.; Muccio, C.; Nguyen, D.; Outhwaite, W.; Petrovan, S. O.; Sutherland, W. J.; Stafford, C.; Tallowin, O.; Safford, R.
10.1101/2023.08.09.552606 — ecology — Posted on 2023-08-12
2904 Scaling laws of human transcriptional activity
Hong, J.; Cavga, A. D.; Shah, D.; Laue, E. D.; Taipale, J.
10.1101/2023.08.10.551625 — genetics — Posted on 2023-08-12
2906 GIS-FA: An approach to integrate thematic maps, factor-analytic and envirotyping for cultivar targeting
Araujo, M. S.; Chaves, S. F. S.; Dias, L. A. S.; Ferreira, F. M.; Pereira, G. R.; Bezerra, A. R. G.; Alves, R. S.; Heinemann, A. B.; Breseghello, F.; Carneiro, P. C. S.; Krause, M. D.; Costa-Neto, G.; Dias, K. O. G.
10.1101/2023.07.15.549137 — genetics — Posted on 2023-08-12
2911 COUP-TFII regulates early bipotential gonad signaling and commitment to ovarian progenitors
Ferreira, L. G. A.; Kizys, M. M. L.; Gama, G. A. C.; Pachernegg, S.; Robevska, G.; Sinclair, A.; Ayers, K. L.; Dias da Silva, M. R.
10.1101/2023.08.09.552582 — developmental biology — Posted on 2023-08-12
2912 Spatiotemporal optical control of Gαq-PLCβ interactions
Ubeysinghe, S.; Kankanamge, D.; Thotamune, W.; Wijayaratna, D.; Mohan, T. M.; Karunarathne, A.
10.1101/2023.08.10.552801 — molecular biology — Posted on 2023-08-12
2917 Development of neonatal connectome dynamics and its prediction for cognitive and language outcomes at age 2
Xu, Y.; Liao, X.; Lei, T.; Cao, M.; Zhao, J.; Zhang, J.; Zhao, T.; Li, Q.; Jeon, T.; Ouyang, M.; Chalak, L.; Rollins, N.; Huang, H.; He, Y.
10.1101/2023.08.07.552267 — neuroscience — Posted on 2023-08-12
2918 Strong and localized recurrence controls dimensionality of neural activity across brain areas
Dahmen, D.; Recanatesi, S.; Jia, X.; Ocker, G. K.; Campagnola, L.; Seeman, S.; Jarsky, T.; Helias, M.; Shea-Brown, E.
10.1101/2020.11.02.365072 — neuroscience — Posted on 2023-08-12
2921 Mesoscopic Oblique Plane Microscopy via Light-sheet Mirroring
Daetwyler, S.; Chang, B.-J.; Chen, B.; Zhou, F. Y.; Fiolka, R. P.
10.1101/2023.08.10.552834 — biophysics — Posted on 2023-08-12
2922 OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Ahdritz, G.; Bouatta, N.; Floristean, C.; Kadyan, S.; Xia, Q.; Gerecke, W.; O'Donnell, T. J.; Berenberg, D.; Fisk, I.; Zanichelli, N.; Zhang, B.; Nowaczynski, A.; Wang, B.; Stepniewska-Dziubinska, M. M.; Zhang, S.; Ojewole, A.; Guney, M. E.; Biderman, S.; Watkins, A. M.; Ra, S.; Lorenzo, P. R.; Nivon, L.; Weitzner, B.; Ban, Y.-E. A.; Sorger, P. K.; Mostaque, E.; Zhang, Z.; Bonneau, R.; AlQuraishi, M.
10.1101/2022.11.20.517210 — bioinformatics — Posted on 2023-08-12
2923 Costs of being a diet generalist in the super-generalist protist predator Dictyostelium discoideum
Shreenidhi, P. M.; Brock, D. A.; McCabe, R. I.; Strassmann, J. E.; Queller, D. C.
10.1101/2023.08.05.552129 — ecology — Posted on 2023-08-12
2925 Aging and senescence-associated analysis of the aged kidney glomerulus highlights the role of mesangial cells in renal aging
Korin, B.; Avraham, S.; McKay, A.; Durinck, S.; Moncada, R.; Menon, H.; Darmanis, S.; Liang, Y.; Modrusan, Z.; Webster, J. D.; Shaw, A. S.
10.1101/2023.08.10.552883 — cell biology — Posted on 2023-08-12
2927 Cyclin B3 is a dominant fast-acting cyclin that drives rapid early embryonic mitoses
Lara-Gonzalez, P.; Variyar, S.; Budrewicz, J.; Schlientz, A.; Varshney, N.; Bellaart, A.; Moghareh, S.; Nguyen, A. C. N.; Oegema, K.; Desai, A.
10.1101/2023.08.11.553011 — cell biology — Posted on 2023-08-12
2928 An adult clock component links circadian rhythms to pancreatic β-cell maturation
Montalvo, A. P.; Gruskin, Z. L.; Leduc, A.; Liu, M.; Gao, Z.; Ahn, J. H.; Straubhaar, J. R.; Slavov, N.; Alvarez-Dominguez, J. R.
10.1101/2023.08.11.552890 — cell biology — Posted on 2023-08-12
2929 Atlas of DES (desmin) variants: Impact of variants located within the head domain on filament assembly
Voss, S.; Walhorn, V.; Holler, S.; Gaertner, A.; Pohl, G.; Gummert, J.; Anselmetti, D.; Milting, H.; Brodehl, A.
10.1101/2023.08.11.552974 — cell biology — Posted on 2023-08-12
2932 The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells
Gonzales, G. A.; Huang, S.; Rajwani, J.; Wilkinson, L.; Nguyen, J. A.; Wood, C. M.; Moore, M.; Cedeno, E.; Sikdar, S.; McKenna, N.; Ebacher, V.; Rosin, N. L.; Carneiro, M. B.; Surewaard, B.; Peters, N. C.; Biernaskie, J.; Mahoney, D. J.; Yates, R. M.; Canton, J.
10.1101/2023.08.11.553042 — cell biology — Posted on 2023-08-12
2933 Heterogeneity of radial spokes structural components and associated enzymes in Tetrahymena cilia
Bicka, M.; Black, C.; Ghanaeian, A.; Joachimiak, E.; Osinka, A.; Majhi, S.; Konopka, A.; Bulska, E.; Bui, K. H.; Wloga, D.
10.1101/2023.08.11.551218 — cell biology — Posted on 2023-08-12
2942 Neuronal Connectivity as a Determinant of Cell Types and Subtypes
Liu, L.; Yun, Z.; Manubens-Gil, L.; Chen, H.; Xiong, F.; Dong, H.; Zeng, H.; Hawrylycz, M.; Ascoli, G. A.; Peng, H.
10.1101/2023.08.09.552547 — neuroscience — Posted on 2023-08-12
2943 Neurons in the human entorhinal cortex map abstract emotion space
Qasim, S. E.; Reinacher, P. C.; Brandt, A.; Schulze-Bonhage, A.; Kunz, L.
10.1101/2023.08.10.552884 — neuroscience — Posted on 2023-08-12
2946 Manipulating the 3D organization of the largest synthetic yeast chromosome
Zhang, W.; Stefanita, L. L.; Yamashita, H.; Shen, M. J.; Mitchell, L. A.; Kurasawa, H.; Lobzaev, E.; Fanfani, V.; Haase, M. A. B.; Sun, X.; Jiang, Q.; Goldberg, G. W.; Ichikawa, D.; Lauer, S. L.; McCulloch, L. H.; Easo, N.; Lin, S. J.; Camellato, B. R.; Zhu, Y.; Cai, J.; Xu, Z.; Zhao, Y.; Sacasa, M.; Accardo, R.; Ahn, J. Y.; Annadanam, S.; Brammer Basta, L. A.; Bello, N.; Cai, L.; Cerritos, S.; Cornwell, M.; D'Amato, A.; Hacker, M.; Hersey, K.; Kennedy, E.; Kianercy, A.; Kim, D.; Lim, H. S.; McCutcheon, G.; McGirr, K.; Meaney, N.; Meyer, L.; Moyer, A.; Nimer, M.; Sabbatini, C.; Shores, L.; Sil
10.1101/2022.04.09.487066 — synthetic biology — Posted on 2023-08-12
2947 Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity
Brodeur, M. N.; Dopeso, H.; Zhu, Y.; Longhini, A. L. F.; Gazzo, A.; Sun, S.; Koche, R.; Qu, R.; Hamard, P.-J.; Bykov, Y.; Green, H.; Chiappinelli, K. B.; Ozsoy, M. A.; Basili, T.; Gardner, R.; Walderich, S.; De Stanchina, E.; Greenbaum, B. D.; Gonen, M.; Weigelt, B.; Zamarin, D.
10.1101/2023.08.08.552544 — cancer biology — Posted on 2023-08-12
2951 Genetic variation in Loudetia simplex supports the presence of ancient grasslands in Madagascar
Tiley, G. P.; Crowl, A. A.; Almary, T. O.; Luke, W. R.; Solofondranohatra, C. L.; Besnard, G.; Lehmann, C. E.; Yoder, A. D.; Vorontsova, M. S.
10.1101/2023.04.07.536094 — evolutionary biology — Posted on 2023-08-11
2952 Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors
Hu, Q.; Espejo Valle-Inclan, J.; Dahiya, R.; Guyer, A.; Mazzagatti, A.; Maurais, E. G.; Engel, J. L.; Cortes-Ciriano, I.; Ly, P.
10.1101/2023.08.10.552800 — cell biology — Posted on 2023-08-11
2955 Ubiquitin phosphorylation accelerates protein aggregation and promotes neurodegeneration in the aging brain
Chen, C.; Yi, H.-W.; Zhang, Y.; Wang, T.; Gao, T.-Y.; Lou, Z.-L.; Wei, T.-F.; Lu, Y.-B.; Li, T.-T.; Zhang, W.-P.; Tang, C.
10.1101/2023.08.10.552882 — cell biology — Posted on 2023-08-12
2956 Aurora A mediated new phosphorylation of RAD51 is observed in Nuclear Speckles
Alaouid, M.; Kenfack Ymbe, P.; Philippot-Menil, V.; Cueff, G.; Demeyer, A.; Marquis, D.; Ayadi, N.; Fleury, F.; Benhelli-Mokrani, H.
10.1101/2023.08.11.552966 — cell biology — Posted on 2023-08-12
2958 Flow cytometry methods for targeted isolation of ctenophore cells
Dieter, A. C.; True, A. B.; Gilbertson, E. A.; Snyder, G.; Lacy-Hulbert, A.; Traylor-Knowles, N.; Browne, W. E.; Vandepas, L. E.
10.1101/2023.08.10.552885 — cell biology — Posted on 2023-08-12
2959 N-glycosylation as a eukaryotic protective mechanism against protein aggregation
Duran-Romana, R.; Houben, B.; De Vleeschouwer, M.; Louros, N.; Wilson, M. P.; Matthijs, G.; Schymkowitz, J.; Rousseau, F.
10.1101/2023.08.11.552904 — molecular biology — Posted on 2023-08-11
2960 Brain-wide representations of prior information in mouse decision-making
Findling, C.; Hubert, F.; International Brain Laboratory, ; Acerbi, L.; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Latham, P. E.; Lau, P. Y. P.; Mainen, Z.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Pan-Vazquez, A.; Paninski, L.; Pillow, J.; Rossant, C.; Roth, N.; Schaeffer,
10.1101/2023.07.04.547684 — neuroscience — Posted on 2023-08-11
2961 Generalization of procedural motor sequence learning after a single practice trial
Johnson, B. P.; Iturrate, I.; Fakhreddine, R. Y.; Bonstrup, M.; Buch, E. R.; Robertson, E. M.; Cohen, L. G.
10.1101/2023.08.08.552542 — neuroscience — Posted on 2023-08-11
2963 Oligodendrocyte precursor cells stop sensory axons regenerating into the spinal cord
Kim, H.; Skuba, A.; Xia, J.; Han, S. B.; Zhai, J.; Hu, H.; Kang, S. H.; Son, Y.-J.
10.1101/2022.09.28.509944 — neuroscience — Posted on 2023-08-11
2964 Spontaneous Mutation in 2310061I04Rik Results in Reduced Expression of Mitochondrial Genes and Impaired Brain Myelination
Tsiitsikov, E. N.; Phan, K.; Liu, Y.; Tsytsykova, A.; Paterno, R.; Sherry, D.; Johnson, A.; Dunn, I.
10.1101/2023.08.10.552737 — neuroscience — Posted on 2023-08-11
2967 Efficient hybrid strategies for assembling the plastome, mitochondriome, and large nuclear genome of diploid Ranunculus cassubicifolius (Ranunculaceae)
Karbstein, K.; Tomasello, S.; Wagner, N. D.; Barke, B. H.; Paetzold, C.; Bradican, J. P.; Preick, M.; Irisarri, I.; de Vries, J.; Hoerandl, E.
10.1101/2023.08.08.552429 — genomics — Posted on 2023-08-11
2969 Stiffness anisotropy coordinates supracellular contractility driving long-range myotube-ECM alignment
Skillin, N. P.; Kirkpatrick, B. E.; Herbert, K. M.; Nelson, B. R.; Hach, G. K.; Gunay, K. A.; Khan, R. M.; DelRio, F. W.; White, T. J.; Anseth, K. S.
10.1101/2023.08.08.552197 — bioengineering — Posted on 2023-08-11
2973 BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
Huchede, P.; Meyer, S.; Berthelot, C.; Hamadou, M.; Bertrand-Chapel, A.; Rakotomalala, A.; MANCEAU, L.; Tomine, J.; Lespinasse, N.; Lewandowski, P.; Cordier-Bussat, M.; Broutier, L.; Dutour, A.; Rochet, I.; Blay, J.-Y.; Degletagne, C.; Attignon, V.; Montero-Carcaboso, A.; Le Grand, M.; Pasquier, E.; Vasiljevic, A.; GILARDI-HEBENSTREIT, P.; Meignan, S.; Leblond, P.; RIBES, V.; Cosset, E.; MARIE, C.
10.1101/2023.08.09.552628 — cancer biology — Posted on 2023-08-11
2974 CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
Li, J.; Hilimire, T. A.; Liu, Y.; Wang, L.; Liang, J.; Gyorffy, B.; Sikirzhytski, V.; Ji, H.; Zhang, L.; Cheng, C.; Ding, X.; Kerr, K. R.; Dowling, C. E.; Chumanevich, A. A.; Schools, G. P.; Lim, C.-u.; Zi, X.; Porter, D. C.; Broude, E. V.; McInnes, C.; Wilding, G.; Lilly, M. B.; Roninson, I. B.; Chen, M.
10.1101/2023.08.08.552491 — cancer biology — Posted on 2023-08-11
2977 Transthyretin has conformation-selective proteolytic activity against α-synuclein
Sarkany, Z.; Giao, T.; Liz, M. A.; Planas, A.; Macedo-Ribeiro, S.; Cardoso, I.; Arsequell, G.; Martins, P. M.
10.1101/2023.08.10.552896 — biochemistry — Posted on 2023-08-11
2980 Molecular basis for short-chain thioester hydrolysis by acyl hydrolase domains in trans-acyltransferase polyketide synthases
Fage, C. D.; Passmore, M.; Tatman, B. P.; Smith, H. G.; Jian, X.; Dissanayake, U. C.; Cisneros, G. A.; Challis, G. L.; Lewandowski, J. R.; Jenner, M.
10.1101/2023.08.11.552765 — biochemistry — Posted on 2023-08-11
2982 Sphingolipid metabolism is spatially regulated in the developing embryo by SOXE genes
Piacentino, M. L.; Fasse, A. J.; Camacho-Avila, A.; Grabylnikov, I.; Bronner, M. E.
10.1101/2023.08.10.552770 — developmental biology — Posted on 2023-08-11
2984 AePUb promoter length modulates gene expression in Aedes aegypti
Anderson, M. A. E.; Leftwich, P. T.; Wilson, R.; Carabajal Paladino, L. Z.; Basu, S.; Rooney, S.; Adelman, Z.; Alphey, L.
10.1101/2023.08.11.553001 — molecular biology — Posted on 2023-08-11
2988 Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes
Zhao, Q.; Duck, L. W.; Killian, J. T.; Rosenberg, A. F.; Mannon, P. J.; King, R. G.; Denson, L. A.; Kugathasan, S.; Janoff, E. N.; Jenmalm, M. C.; Elson, C. O.
10.1101/2023.08.08.552496 — immunology — Posted on 2023-08-11
2991 Non-ablative disease-modifying effects of magnetic resonance-guided focused ultrasound in neuromelanin-producing parkinsonian rodents
Compte, J.; Tible, M.; Cuadros, T.; Romero-Jimenez, J.; Laguna, A.; Aubry, J.-F.; Dumont, E.; Constans, C.; Tiennot, T.; Santin, M. D.; Lehericy, S.; Vila, M.
10.1101/2023.08.08.552410 — neuroscience — Posted on 2023-08-11
2992 Neolactotetraosylceramide: A novel non-invasive urinary biomarker for bladder cancer
Moreira, I. B.; Rossdam, C.; Beimdiek, J.; Vicente, M. M.; Schmitz, J.; Oberbeck, A.; Braesen, J. H.; Tezval, H.; Buettner, F. F. R.
10.1101/2023.08.08.552442 — cancer biology — Posted on 2023-08-11
2995 Biophysical analysis reveals autophosphorylation as an important negative regulator of LRRK2 dimerization
Guaitoli, G.; Zhang, X.; Saitta, F.; Miglionico, P.; Silbermann, L. M.; Ho, F. Y.; von Zweydorf, F.; Signorelli, M.; Tych, K.; Fessas, D.; Raimondi, F.; Kortholt, A.; Gloeckner, C. J.
10.1101/2023.08.11.549911 — biochemistry — Posted on 2023-08-11
2998 One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes
Ye, Z.; Sabatier, P.; Martin-Gonzalez, J.; Eguchi, A.; Bekker-Jensen, D. B.; Bache, N.; Olsen, J. V.
10.1101/2023.08.10.552756 — biochemistry — Posted on 2023-08-11
2999 Bifunctional Monosaccharides Preferentially Localize to Nuclear Subcompartments
Barahtjan, P.; Iglesias-Artola, J. M.; Boehlig, K.; Lohmann, A.; Nadler, A.
10.1101/2023.08.11.552905 — biochemistry — Posted on 2023-08-11
3000 Metal Ions Guide the Production of Silkworm Fibers
Brookstein, O.; Shimoni, E.; Eliaz, D.; Kaplan-Ashiri, I.; Carmel, I.; Shimanovich, U.
10.1101/2023.08.10.552775 — biochemistry — Posted on 2023-08-11
3002 An evolutionary timescale for Bacteria calibrated using the Great Oxidation Event
Davin, A. A.; Woodcroft, B. J.; Soo, R. M.; Murali, R.; Schrempf, D.; Clark, J.; Boussau, B.; Moody, E. R. R.; Szantho, L. L.; Richy, E.; Pisani, D.; Hemp, J.; Fischer, W. W.; Donoghue, P.; Spang, A.; Hugenholtz, P.; Williams, T. A.; Szöllosi, G. J.
10.1101/2023.08.08.552427 — evolutionary biology — Posted on 2023-08-11
3003 Short oligomers rather than rings of human RAD52 promote single-strand annealing
Kharlamova, M. A.; Kushwah, M. S.; Jachowski, T. J.; Subramaniam, S.; Stewart, A. F.; Kukura, P.; Schäffer, E.
10.1101/2023.08.11.553006 — molecular biology — Posted on 2023-08-11
3004 Dietary cystine restriction increases the proliferative capacity of the small intestine of mice
de Jong, J.; Ijssennagger, N.; van Rooijen, K.; Stigter, E.; Gülersönmez, C.; de Zoete, M.; Top, J.; Baars, M.; Vercoulen, Y.; Kuipers, F.; van Mil, S.
10.1101/2023.08.10.552836 — molecular biology — Posted on 2023-08-11
3005 Microbial eukaryotic predation pressure and biomass at deep-sea hydrothermal vents: Implications for deep-sea carbon cycling
Hu, S. K.; Anderson, R. E.; Pachiadaki, M. G.; Edgcomb, V. P.; Serres, M. H.; Sylva, S. P.; German, C. R.; Seewald, J. S.; Lang, S. Q.; Huber, J. A.
10.1101/2023.08.11.552852 — microbiology — Posted on 2023-08-11
3006 The PP1 phosphatase exhibits pleiotropic roles controlling both the tachyzoite cell cycle and amylopectin-steady state levels in Toxoplasma gondii.
Khelifa, A. S.; Boissavy, T.; Mouveaux, T.; Araujo Silva, T.; Chhuon, C.; Attias, M.; Guerrera, I. C.; De Souza, W.; Dauvillee, D.; Roger, E.; GISSOT, M.
10.1101/2023.08.10.552784 — microbiology — Posted on 2023-08-11
3008 Additive Manufacturing Leveraged Microfluidic Setup for Sample to Answer Colorimetric Detection of Pathogens
Yedire, S. G.; Hosseini, I. I.; Shieh, H.; Jahromi, A. K.; Fatah, T. A.; Jalali, M.; Mahshid, S.
10.1101/2023.08.10.552726 — bioengineering — Posted on 2023-08-11
3010 NUCLEOPORIN1 mediates proteasome-based degradation of ABI5 to regulate Arabidopsis seed germination
Thapa, R. K.; Tian, G.; Lu, Q. S. M.; Yu, Y.; Shu, J.; Chen, C.; Song, J.; Xie, X.; Shan, B.; Nguyen, V.; Li, C.; Bian, S.; Liu, J.; Kohalmi, S. E.; Cui, Y.
10.1101/2023.08.10.552853 — plant biology — Posted on 2023-08-11
3014 Profound disease modification and seizure suppression by targeting JAK1, a key driver of a pro-epileptogenic gene network
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A. S.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-08-11
3017 GreenMemTraX: A User-Friendly Software for Super-Resolution Analysis of Membrane Protein Dynamics and Nanoscale Organization in Plants
Rohr, L.; Ehinger, A.; Rausch, L.; Burmeister, N. G.; Meixner, A. J.; Harter, K.; Kemmerling, B.; zur Oven-Krockhaus, S.
10.1101/2023.08.10.552827 — plant biology — Posted on 2023-08-11
3019 Bronchoconstriction damages airway epithelia by excess crowding-induced extrusion
Bagley, D. C.; Russell, T.; Ortiz-Zapater, E.; Fox, K.; Redd, P. F.; Joseph, M.; Rice, C. D.; Reilly, C. A.; Parsons, M.; Rosenblatt, J.
10.1101/2023.08.04.551943 — cell biology — Posted on 2023-08-11
3021 Pynapple, a toolbox for data analysis in neuroscience.
Viejo, G.; Levenstein, D.; Carrasco, S. S.; Mehrotra, D.; Mahallati, S.; Vite, G. R.; Denny, H.; Sjulson, L.; Battaglia, F. P.; Peyrache, A.
10.1101/2022.12.06.519376 — neuroscience — Posted on 2023-08-11
3024 Divergent roles of IREG/Ferroportin transporters from the nickel hyperaccumulator Leucocroton havanensis
Alfonso Gonzalez, D.; Sanchez Garcia de laTorre, V.; Reyes Fernandez, R.; Barreau, L.; MERLOT, S.
10.1101/2023.08.11.552958 — plant biology — Posted on 2023-08-11
3025 Isoform-specific aPKC renders primary cilia dispensable for Hedgehog signaling and basal cell carcinoma growth
Nguyen, T. T.; Wong, K.; Jeon, U. S.; Jhumkhawala, V.; Luy, D.; Tan, K. C.; Wickramatunga, I.; Kumar, V.; England, W. E.; Doan, L. T.; Spitale, R. C.; Atwood, S. X.
10.1101/2020.06.08.137216 — cancer biology — Posted on 2023-08-11
3026 Reconstructing stochastic cell population trajectories reveals regulators and heterogeneity of endothelial flow-migration coupling driving vascular remodelling
Giese, W.; Rosa, A.; Baumann, E.; Oppenheim, O.; Akmeric, E. B.; Andrade, S.; Hollfinger, I.; Bartels-Klein, E.; Alt, S.; Gerhardt, H.
10.1101/2023.05.30.542799 — developmental biology — Posted on 2023-08-11
3028 MiR-155 epigenetically counteracts hypoxia for mitochondrial fitness during germinal center positive selection
Nakagawa, R.; Llorian, M.; Varsani-brown, S.; Chakravarty, P.; Camarillo, J. M.; Barry, D.; George, R.; Blackledge, N. P.; Duddy, G.; Kelleher, N. L.; Klose, R. J.; Turner, M.; Calado, D. P.
10.1101/2023.07.31.551250 — immunology — Posted on 2023-08-11
3029 EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS
Urban, M. W.; Charsar, B. A.; Heinsinger, N. M.; Markandaiah, S. S.; Sprimont, L.; Zhou, W.; Brown, E. V.; Henderson, N. T.; Thomas, S. J.; Ghosh, B.; Cain, R. E.; Trotti, D.; Pasinelli, P.; Wright, M. C.; Dalva, M. B.; Lepore, A. C.
10.1101/2023.05.10.538887 — neuroscience — Posted on 2023-08-11
3032 Functional and anatomical connectivity predict brain stimulation's mnemonic effects
Ezzyat, Y.; Kragel, J. E.; Solomon, E. A.; Lega, B. C.; Aronson, J. P.; Jobst, B. C.; Gross, R. E.; Sperling, M. R.; Worrell, G. A.; Sheth, S. A.; Wanda, P. A.; Rizzuto, D. S.; Kahana, M. J.
10.1101/2023.07.27.550851 — neuroscience — Posted on 2023-08-11
3033 MC1R reduces scarring and rescues stalled healing in a novel preclinical chronic wound model
Rocliffe, H. R.; Austin-Williams, S.; Krilis, G.; Nawilaijaroen, Y.; Pellicoro, A.; Zhou, K.; Ji, Y.; Bain, C.; Zhou, T.; Crichton, M.; Huang, Z.; Caporali, A.; Cash, J. L.
10.1101/2022.11.30.518516 — pathology — Posted on 2023-08-11
3035 T:B cell cooperation in ectopic lymphoid follicles propagates CNS autoimmunity
Kolz, A.; Bauer, I. J.; de la Rosa, C.; Kavaka, V.; Thomann, A. S.; Schmitz, R.; Kerschensteiner, M.; Beltran, E.; Kawakami, N.; Peters, A.
10.1101/2023.06.01.543004 — immunology — Posted on 2023-08-11
3037 SMB controls decompartmentalization in Arabidopsis root cap cells to execute programmed cell death
Wang, J.; BOLLIER, N.; Andrade Buono, R.; Vahldick, H.; Lin, Z.; Feng, Q.; Hudecek, R.; JIANG, Q.; Mylle, E.; Van Damme, D.; Nowack, M. K.
10.1101/2023.08.10.552584 — plant biology — Posted on 2023-08-11
3039 Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis
Daum, A.-K.; Schlicker, L.; Schneider, M. A.; Muley, T.; Klingmüller, U.; Schulze, A.; Thomas, M.; Christopoulos, P.; Sültmann, H.
10.1101/2023.08.08.552439 — cancer biology — Posted on 2023-08-11
3043 Mesothelial cells exhibit characteristics of perivascular cells in an in vitro angiogenesis assay
Koukorava, C.; Ward, K.; Ahmed, K.; Dauleh, S.; Pereira, S.; Taylor, A.; Haddrick, M.; Cross, M.; Wilm, B.
10.1101/2023.08.11.552910 — cell biology — Posted on 2023-08-11
3047 Transcriptional suppression of sphingolipid catabolism controls pathogen resistance in C. elegans
Nasrallah, M. A.; Peterson, N. D.; Salisbury, J. E.; Liu, P.; Page, A. L.; Tse, S. Y.; Wani, K. A.; Tocheny, C. E.; Pukkila-Worley, R.
10.1101/2023.08.10.552843 — immunology — Posted on 2023-08-11
3056 ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid condensates
Vale-Costa, S.; Etibor, T. A.; Bras, D.; Sousa, A. L.; Ferreira, M.; Martins, G. G.; Mello, V. H.; Amorim, M. J.
10.1101/2022.12.21.521536 — cell biology — Posted on 2023-08-11
3059 Somatic mutation rates scale with time not growth rate in long-lived tropical trees
Satake, A.; Imai, R.; Fujino, T.; Tomimoto, S.; Ohta, K.; Na'iem, M.; Indrioko, S.; Widiyatno, W.; Purnomo, S.; Morales, A. M.; Nizhynska, V.; Tani, N.; Suyama, Y.; Sasaki, E.; Kasahara, M.
10.1101/2023.01.26.525665 — evolutionary biology — Posted on 2023-08-11
3060 An open-source FACS automation system for high-throughput cell biology
Wiener, D. M.; Huynh, E.; Jeyakumar, I.; Bax, S.; Sama, S.; Cabrera, J. P.; Todorova, V.; Vangipuram, M.; Vaid, S.; Otsuka, F.; Sakai, Y.; Leonetti, M. D.; Gomez-Sjoberg, R.
10.1101/2023.03.24.534165 — bioengineering — Posted on 2023-08-11
3062 Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α
Molinaro, G.; Bowles, J. E.; Croom, K.; Gonzalez, D.; Mirjafary, S.; Birnbaum, S.; Razak, K. A.; Gibson, J. R.; Huber, K. M.
10.1101/2023.08.10.552857 — neuroscience — Posted on 2023-08-10
3063 Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive
Hochbaum, D. R.; Dubinsky, A. C.; Farnsworth, H. C.; Hulshof, L.; Kleinberg, G.; Urke, A.; Wang, W.; Hakim, R.; Robertson, K.; Park, C.; Solberg, A.; Yang, Y.; Baynard, C.; Nadaf, N. M.; Beron, C.; Girasole, A.; Chantranupong, L.; Cortopassi, M.; Prouty, S.; Geistlinger, L.; Banks, A.; Scanlan, T.; Greenberg, M.; Boulting, G. L.; Macosko, E.; Sabatini, B. L.
10.1101/2023.08.10.552874 — neuroscience — Posted on 2023-08-10
3064 BRAT1 associates with INTS11/INTS9 heterodimer to regulate key neurodevelopmental genes
Dokaneheifard, S.; Shiekhattar, R.; Gomes Dos Santos, H.; Valencia, M. G.; Arigela, H.
10.1101/2023.08.10.552743 — biochemistry — Posted on 2023-08-10
3065 Ancient Mongolian aurochs genomes reveal sustained introgression and management in East Asia
Brunson, K.; Witt, K. E.; Monge, S.; Williams, S.; Peede, D.; Odsuren, D.; Bukhchuluun, D.; Cameron, A.; Szpak, P.; Amartuvshin, C.; Honeychurch, W.; Wright, J.; Pleuger, S.; Erdene, M.; Tumen, D.; Rogers, L.; Khatanbaatar, D.; Batdalai, B.; Galdan, G.; Janz, L.
10.1101/2023.08.10.552443 — genomics — Posted on 2023-08-10
3068 Within-Individual Organization of the Human Cerebral Cortex: Networks, Global Topography, and Function
Du, J.; DiNicola, L. M.; Angeli, P. A.; Saadon-Grosman, N.; Sun, W.; Kaiser, S.; Ladopoulou, J.; Xue, A.; Yeo, B. T. T.; Eldaief, M. C.; Buckner, R. L.
10.1101/2023.08.08.552437 — neuroscience — Posted on 2023-08-10
3069 A novel quantification method for RPE phagocytosis using a VLC-PUFA-based strategy
Gao, F.; Tom, E.; Lieffrig, S. A.; Finnemann, S. C.; Skowronska-Krawczyk, D.
10.1101/2022.07.02.498584 — biochemistry — Posted on 2023-08-10
3070 The heme exporter FLVCR regulates mitochondrial biogenesis and redox balance in the hematophagous insect Rhodnius prolixus
Walter-Nuno, A. B.; Taracena-Agarwal, M.; Oliveira, M. P.; Oliveira, M.; Oliveira, P. L.; Paiva-SIlva, G. O.
10.1101/2023.08.07.552335 — biochemistry — Posted on 2023-08-10
3071 A harmonized public resource of deeply sequenced diverse human genomes
Koenig, Z.; Yohannes, M. T.; Nkambule, L. L.; Goodrich, J. K.; Kim, H. A.; Zhao, X.; Wilson, M. W.; Tiao, G.; Hao, S. P.; Sahakian, N.; Chao, K. R.; gnomAD Project Consortium, ; Rehm, H.; Neale, B.; Talkowski, M. E.; Daly, M. J.; Brand, H.; Karczewski, K.; Atkinson, E. G.; Martin, A.
10.1101/2023.01.23.525248 — genomics — Posted on 2023-08-10
3073 The effects of reference panel perturbations on the accuracy of genotype imputation
Li, J. H.; Liu, A.; Buerkle, C. A.; Palmer, W.; Belbin, G. M.; Ahangari, M.; Gibson, M. J.; Flagel, L.
10.1101/2023.08.10.552684 — genomics — Posted on 2023-08-10
3076 A dynamic in vitro model of Down Syndrome neurogenesis with Trisomy 21 gene dosage correction
Bansal, P.; Banda, E. C.; Glatt-Deeley, H. R.; Stoddard, C.; Linsley, J. W.; Arora, N.; Ahern, D. T.; Kondaveeti, Y.; Nicouleau, M.; Sabariego-Navarro, M.; Dierssen, M.; Finkbeiner, S.; Pinter, S. F.
10.1101/2022.05.11.491519 — developmental biology — Posted on 2023-08-10
3078 Validation of an antigenic site targeted by monoclonal antibodies against Puumala virus
Plyusnin, A.; Kedari, A.; Rissanen, I.; Iheozor-Ejiofor, R. P.; Lundkvist, A.; Vapalahti, O.; Levanov, L.
10.1101/2023.08.10.552746 — molecular biology — Posted on 2023-08-10
3079 Pisces: A multi-modal data augmentation approach for drug combination synergy prediction
Xu, H.; Lin, J.; Woicik, A.; Liu, Z.; Ma, J.; Zhang, S.; Poon, H.; Wang, L.; Wang, S.
10.1101/2022.11.21.517439 — molecular biology — Posted on 2023-08-10
3080 Structural basis of archaeal FttA-dependent transcription termination
Wang, C.; Molodtsov, V.; Sanders, T. J.; Marshall, C. J.; Firlar, E.; Kaelber, J. T.; Santangelo, T. J.; Ebright, R. H.
10.1101/2023.08.09.552649 — molecular biology — Posted on 2023-08-10
3082 Metabolic changes to host cells with Toxoplasma gondii infection
Gallego-Lopez, G. M.; Contreras Guzman, E.; Knoll, L.; Skala, M. C.
10.1101/2023.08.10.552811 — microbiology — Posted on 2023-08-10
3084 PII signal transduction superfamily acts as a valve plug to control bicarbonate and ammonia homeostasis among different bacterial phyla
Haffner, M.; Hou, W.-T.; Mantovani, O.; Walke, P. R.; Hauf, K.; Borisova, M.; Hagemann, M.; Zhou, C.-Z.; Forchhammer, K.; Selim, K. A.
10.1101/2023.08.10.552651 — microbiology — Posted on 2023-08-10
3086 De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
Koh, J.; Woo, Y. D.; Yoo, H. J.; Choi, J.-P.; Kim, S. H.; Chang, Y.-S.; Jung, K. C.; Kim, J. H.; Jeon, Y. K.; Kim, H. Y.; Chung, D. H.
10.1101/2023.02.15.528598 — immunology — Posted on 2023-08-10
3088 VMHdm/cSF-1 Neuronal Circuits Regulate Skeletal Muscle PGC1-α via the Sympathoadrenal Drive
Takuya, T.; Fujitani, M.; Farmer, S.; Harada, A.; Shi, Z.; Lee, J. J.; Tinajero, A.; Singha, A. K.; Fujikawa, T.
10.1101/2022.04.01.486756 — neuroscience — Posted on 2023-08-10
3089 Thiazolidinediones are partially effective bitter blockers
Nguyen, H.; Lin, C.; Sasimovich, I.; Bell, K.; Huang, A.; Leszkowicz, E.; Rawson, N.; Reed, D. R.
10.1101/2023.08.08.552460 — physiology — Posted on 2023-08-10
3091 In vivo Mapping of Cellular Resolution Neuropathology in Brain Ischemia by Diffusion MRI
Wu, D.; Turnbill, V.; Lee, H.-H.; Wang, X.; Ba, R.; Walczak, P.; Martin, L. J.; Fieremans, E.; Novikov, D. S.; Northington, F. J.; Zhang, J.
10.1101/2023.08.08.552374 — bioengineering — Posted on 2023-08-10
3092 Defective Function of α-Ketoglutarate Dehydrogenase Exacerbates Mitochondrial ATP Deficits during Complex I Deficiency
Piroli, G. G.; Manuel, A. M.; McCain, R. S.; Smith, H. H.; Ozohanics, O.; Mellid, S.; Cotham, W. E.; Walla, M. D.; Cascon, A.; Ambrus, A.; Frizzell, N.
10.1101/2020.01.09.900514 — biochemistry — Posted on 2023-08-10
3094 The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products
Garb, J.; Amitai, G.; Lu, A.; Ofir, G.; Brandis, A.; Mehlman, T.; Kranzusch, P.; Sorek, R.
10.1101/2023.08.10.552750 — molecular biology — Posted on 2023-08-10
3095 Mycobacterial formation of intracellular lipid inclusions is a dynamic process associated with rapid replication
Fines, D. M.; Schichnes, D.; Knight, M.; Anaya-Sanchez, A.; Thuong, N. T. T.; Cox, J. S.; Stanley, S.
10.1101/2023.08.10.552809 — microbiology — Posted on 2023-08-10
3096 Sub-nucleolar trafficking of Hendra virus matrix protein is regulated by ubiquitination and oligomerisation
Rawlinson, S. M.; Zhao, T.; David, C. T.; Veuglers, P. F.; Rozario, A. M.; Bell, T. D. M.; Moseley, G. W.
10.1101/2023.08.10.552741 — microbiology — Posted on 2023-08-10
3097 Plasma Glycomic Markers of Accelerated Biological Aging During Chronic HIV Infection
Giron, L. B.; Liu, Q.; Adeniji, O. S.; Yin, X.; Kannan, T.; Ding, J.; Lu, D. Y.; Langan, S.; Zhang, J.; Azevedo, J. L. L. C.; Hanna, D. B.; Ofotokun, I.; Lazar, J.; Fischl, M. A.; Haberlen, S.; Macatangay, B.; Adimora, A. A.; Jamieson, B. D.; Rinaldo, C.; Merenstein, D.; Roan, N. R.; Kutsch, O.; Gange, S.; Wolinsky, S.; Witt, M.; Post, W. S.; Kossenkov, A.; Landay, A.; Frank, I.; Tien, P. C.; Gross, R.; Brown, T. T.; Mohsen, M. A.
10.1101/2023.08.09.551369 — microbiology — Posted on 2023-08-10
3098 The Toxoplasma subpellicular network is highly interconnected and defines parasite shape for efficient motility and replication
Back, P. S.; Senthilkumar, V.; Choi, C. P.; Ly, A. M.; Snyder, A. K.; Lau, J. G.; Ward, G. E.; Bradley, P. J.
10.1101/2023.08.10.552545 — microbiology — Posted on 2023-08-10
3099 HIV-Tocky system to visualize proviral expression dynamics
Reda, O.; Monde, K.; Sugata, K.; Rahman, A.; Sakhor, W.; Rajib, S. A.; Sithi, S. N.; Tan, B. J. Y.; Niimura, K.; Motozono, C.; Maeda, K.; Ono, M.; Takeuchi, H.; Satou, Y.
10.1101/2023.08.10.552733 — microbiology — Posted on 2023-08-10
3100 Parametric information about eye movements is sent to the ears
Lovich, S. N.; King, C. D.; Murphy, D. L. K.; Landrum, R.; Shera, C. A.; Groh, J. M.
10.1101/2022.11.27.518089 — neuroscience — Posted on 2023-08-10
3101 Profound disease modification and seizure suppression by targeting JAK1, a key driver of a pro-epileptogenic gene network
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-08-10
3105 Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes
Yoon, P. H.; Skopintsev, P.; Shi, H.; Chen, L.-X.; Adler, B. A.; Al-Shimary, M.; Craig, R. J.; Li, Z.; Amerasekera, J.; Trinidad, M.; Nisonoff, H.; Chen, K.; Lahiri, A.; Boger, R.; Jacobsen, S.; Banfield, J. F.; Doudna, J. A.
10.1101/2023.08.09.552727 — molecular biology — Posted on 2023-08-10
3106 Concurrent D-loop cleavage by Mus81 and Yen1 yields half-crossover precursors
Carreira, R.; Aguado, F. J.; Crugeiras, M.; Sebesta, M.; Krejci, L.; Blanco, M. G.
10.1101/2023.08.10.552596 — molecular biology — Posted on 2023-08-10
3108 Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis
Xie, O.; Morris, J. M.; Hayes, A. J.; Towers, R. J.; Jespersen, M. G.; Lees, J. A.; Ben Zakour, N. L.; Berking, O.; Baines, S. L.; Carter, G. P.; Tonkin-Hill, G.; Schrieber, L.; McIntyre, L.; Lacey, J. L.; James, T. B.; Sriprakash, K. S.; Beatson, S. A.; Hasegawa, T.; Giffard, P.; Steer, A. C.; Batzloff, M. R.; Beall, B. W.; Pinho, M. D.; Ramirez, M.; Bessen, D. E.; Dougan, G.; Bentley, S. D.; Walker, M. J.; Currie, B. J.; Tong, S. Y.; McMillan, D. J.; Davies, M. R.
10.1101/2023.08.10.552873 — microbiology — Posted on 2023-08-10
3113 Mode of carbon and energy metabolism shifts lipid composition in the thermoacidophile Acidianus
Rhim, J. H.; Zhou, A.; Amenabar, M. J.; Elling, F. J.; Weber, Y.; Pearson, A.; Boyd, E.; Leavitt, W. D.
10.1101/2023.08.10.552821 — microbiology — Posted on 2023-08-10
3115 Unravelling the landscape of antibiotic resistance determinants in the nasopharynx and the impact of antibiotics: a longitudinal study of preterm infants
Dhariwal, A.; Rajar, P.; Salvadori, G.; Amdal, H. A.; Berild, D.; Saugstad, O. D.; Fugelseth, D.; Greisen, G.; Dahle, U.; Haaland, K.; Petersen, F. C.
10.1101/2023.08.09.552435 — microbiology — Posted on 2023-08-10
3116 Microbiome Analysis of the Eastern Oyster As a Function of Ploidy and Seasons
Pathak, A.; Marquez, M.; Stothard, P.; Chukwujindu, C.; Su, J.-Q.; Zhou, Y.; Zhou, X.-Y.; Jagoe, C. H.; Chauhan, A.
10.1101/2023.08.10.552804 — microbiology — Posted on 2023-08-10
3119 Cell division machinery drives cell-specific gene activation during bacterial differentiation
Chareyre, S.; Li, X.; Anjuwon-Foster, B. R.; Clifford, S.; Brogan, A.; Su, Y.; Shroff, H.; Ramamurthi, K. S.
10.1101/2023.08.10.552768 — microbiology — Posted on 2023-08-10
3121 Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization
Ringe, R. P.; Colin, P.; Ozorowski, G.; Allen, J.; Yasmeen, A.; Seabright, G.; Lee, J. H.; Antanasijevic, A.; Rantalainen, K.; Ketas, T.; Moore, J.; Ward, A.; Crispin, M.; Klasse, P. J.
10.1101/2023.08.08.552396 — immunology — Posted on 2023-08-10
3122 Systems-ecology designed bacterial consortium protects from severe Clostridioides difficile infection
Jenior, M. L.; Leslie, J. L.; Kolling, G. L.; Archbald-Pannone, L.; Powers, D. A.; Petri, W. A.; Papin, J. A.
10.1101/2023.08.08.552483 — systems biology — Posted on 2023-08-10
3125 The reference genome of the paradise fish (Macropodus opercularis)
Fodor, E.; Okendo, J.; Szabo, N.; Szabo, K.; Czimer, D.; Tarjan-Racz, A.; Szeverenyi, I.; Low, B. W.; Liew, J. H.; Koren, S.; Rhie, A.; Orban, L.; Miklosi, A.; Varga, M.; Burgess, S. M.
10.1101/2023.08.10.552018 — genomics — Posted on 2023-08-10
3127 The effects of reference panel perturbations on the accuracy of genotype imputation
Li, J. H.; Liu, A.; Buerkle, C. A.; Palmer, W.; Belbin, G. M.; Ahangari, M.; Gibson, M. J.; Flagel, L.
10.1101/2023.08.10.552684 — genomics — Posted on 2023-08-10
3129 GenomeMUSter mouse genetic variation service enables multi-trait, multi-population data integration and analyses
Ball, R. L.; Bogue, M. A.; Liang, H.; Srivastava, A.; Ashbrook, D. G.; Lamoureux, A.; Gerring, M. W.; Hatoum, A. S.; Kim, M. J.; He, H.; Emerson, J.; Berger, A. K.; Walton, D. O.; Sheppard, K.; El Kassaby, B.; Castellanos, F.; Ramamoorthy, G.; Lu, L.; Bluis, J.; Desai, S.; Sundberg, B. A.; Peltz, G.; Fang, Z.; Churchill, G. A.; Williams, R. W.; Agrawal, A.; Bult, C. J.; Philip, V. M.; Chesler, E. J.
10.1101/2023.08.08.552506 — genetics — Posted on 2023-08-10
3130 Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model
Blaeser, A. S.; Zhao, J.; Sugden, A. U.; Carneiro-Nascimento, S.; Andermann, M. L.; Levy, D.
10.1101/2023.07.31.549838 — neuroscience — Posted on 2023-08-10
3134 Microbiome single cell atlases generated with a commercial instrument
Li, X.; Xu, L.; Demaree, B.; Noecker, C.; Bisanz, J. E.; Weisgerber, D. W.; Modavi, C.; Turnbaugh, P. J.; Abate, A. R.
10.1101/2023.08.08.551713 — bioengineering — Posted on 2023-08-10
3135 Development and Analytical Evaluation of a Point-of-Care Electrochemical Biosensor for Rapid and Accurate SARS-CoV-2 Detection
Meshesha, M.; Sardar, A.; Supekar, R.; Bhattacharjee, L.; Chatterjee, S.; Halder, N.; Mohanta, K.; Pal, B.
10.1101/2023.08.08.552470 — bioengineering — Posted on 2023-08-10
3136 Open-source milligram-scale, four channel, automated protein purification system
Puccinelli, R. R.; Sama, S. S.; Worthington, C. M.; Puschnik, A. S.; Pak, J. E.; Gomez-Sjoberg, R.
10.1101/2023.08.09.552685 — bioengineering — Posted on 2023-08-10
3141 Innovation and elaboration on the avian tree of life
Guillerme, T.; Bright, J.; Cooney, C.; Hughes, E. C.; Varley, Z.; Cooper, N.; Beckerman, A. P.; Thomas, G. H.
10.1101/2022.08.12.503188 — evolutionary biology — Posted on 2023-08-10
3143 DHA shortage causes the early degeneration of photoreceptors and RPE in mice with peroxisomal β-oxidation deficiency
Swinkels, D.; Kocherlakota, S.; Das, Y.; Dane, A. D.; Wever, E. J. M.; Vaz, F. M.; Bazan, N. G.; Van Veldhoven, P. P.; Baes, M.
10.1101/2023.08.09.552578 — cell biology — Posted on 2023-08-10
3146 Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex
Murphy, K. E.; Duncan, B. W.; Sperringer, J. E.; Zhang, E. Y.; Haberman, V. A.; Wyatt, E. V.; Maness, P. F.
10.1101/2023.07.11.548527 — neuroscience — Posted on 2023-08-10
3147 Synthetic chromosome fusion: effects on genome structure and function
Luo, J.; Vale-Silva, L. A.; Raghavan, A. R.; Mercy, G.; Heldrich, J.; Sun, X.; Li, M.; Zhang, W.; Agmon, N.; Yang, K.; Cai, J.; Stracquadanio, G.; Thierry, A.; Zhao, Y.; Coelho, C.; Lauer, S.; Ahn, J. Y.; Adoff, G.; D'Avino, A.; Berger, H.; Chen, Y.; Chickering, M.; Fishman, O.; Greeno, R. V.; Kim, S.; Kim, S.; Lim, H. S.; Im, J.; Meyer, L.; Moyer, A.; Annadanam, S.; Murphy, N. A.; Natov, P.; Nimer, M.; Radley, A.; Tripathy, A.; Wang, T.; Wilkerson, N.; Zheng, T.; Zhou, V.; Zeller, K.; Kaback, D. B.; Bader, J. S.; Mitchell, L. A.; Mozziconacci, J.; Koszul, R.; Hochwagen, A.; Boeke, J. D.
10.1101/381137 — synthetic biology — Posted on 2023-08-10
3151 MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins
Seo, T.; Lowery, A. M.; Xu, H.; Giang, W.; Troyanovsky, S. M.; Vincent, P. A.; Kowalczyk, A. P.
10.1101/2023.08.10.552739 — cell biology — Posted on 2023-08-10
3152 Golgi membrane proteins YIPF3 and YIPF4 regulate turnover of the Golgi apparatus through autophagy
Kitta, S.; Kaminishi, T.; Higashi, M.; Shima, T.; Kosako, H.; Yoshimori, T.; Kuma, A.
10.1101/2023.08.09.552599 — cell biology — Posted on 2023-08-10
3156 Uranium-bearing dust induces differentiation and expansion of enteroendocrine cells in human colonoids
Atanga, R.; Appell, L. L.; Lauer, F. T.; Brearley, A.; Campen, M. J.; Castillo, E. F.; In, J. G.
10.1101/2023.08.10.552796 — cell biology — Posted on 2023-08-10
3157 Ablation of oligodendrogenesis in adult mice alters brain microstructure and activity independently of behavioural deficits
Kaller, M. S.; Lazari, A.; Feng, Y.; van der Toorn, A.; Ruehling, S.; Thomas, C. W.; Shimizu, T.; Bannerman, D. M.; Vyazovskiy, V.; Richardson, W. D.; Sampaio-Baptista, C.; Johansen-Berg, H.
10.1101/2023.07.06.547854 — neuroscience — Posted on 2023-08-10
3159 Identification of novel myeloid-derived cell states with implication in cancer outcome
Guimaraes, G. R.; Maklouf, G. R.; Teixeira, C. E.; de Oliveira Santos, L.; Tessarollo, N. G.; Pretti, M. A. M.; Toledo, N. E.; da Cruz, J. G. V.; Falchetti, M.; Dimas, M. M.; Serain, A. F.; de Macedo, F. C.; Rodrigues, F. R.; Bastos, N. C.; da Silva, J. L.; Lummertz-Rocha, E.; Chaves, C. B. P.; de Melo, A. C.; Moraes-Vieira, P. M. M.; Mori, M. A.; Boroni, M.
10.1101/2023.01.04.522727 — cancer biology — Posted on 2023-08-10
3162 Exogenous corticosterone administration during pregnancy alters placental and fetal thyroid hormone availability in females.
Paul, E. N.; Shubitidze, S.; Rahim, R.; Rucker, I.; Valin, L.; Apostle, S.; Pospisilik, J. A.; Racicot, K. E.; Smith, A. L.
10.1101/2023.07.05.547278 — developmental biology — Posted on 2023-08-10
3163 Mobile version of the Battery for the Assessment of Auditory Sensorimotor and Timing Abilities (BAASTA): Implementation and adult norms
Dalla Bella, S.; Foster, N.; Laflamme, H.; Zagala, A.; Kadi, M.; Komeilipoor, N.; Blais, M.; Rigoulot, S.; Kotz, S. A.
10.1101/2023.07.21.550031 — neuroscience — Posted on 2023-08-10
3165 The Mediterranean mussel, Mytilus galloprovincialis, a novel model for developmental studies of mollusks
Miglioli, A.; Tredez, M.; Boosten, M.; Sant, C.; Carvalho, J. E.; Dru, P.; Canesi, L.; Schubert, M.; Dumollard, R.
10.1101/2023.07.27.550798 — developmental biology — Posted on 2023-08-10
3166 Microtomographic investigation of a large corpus of cichlids
Haberthür, D.; Law, M.; Ford, K.; Häsler, M.; Seehausen, O.; Hlushchuk, R.
10.1101/2023.03.30.534917 — ecology — Posted on 2023-08-10
3169 The endosomal sorting complex Retromer has a central role insystemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
Vos, D. Y.; Barbosa, M. G.; Heida, A. H.; Rios-Ocampo, W. A.; Tissink, J. J.; Koster, M. H.; Smit, M.; Huijkman, N.; Kloosterhuis, N. J.; Havinga, R.; Fuh, M. M.; Jonker, J. W.; Reggiori, F.; Mari, M.; Scheja, L.; Heeren, J.; Kuipers, F.; de Boer, J. F.; Wolters, J. C.; Kuivenhoven, J. A.; van de Sluis, B.
10.1101/2023.08.09.552611 — molecular biology — Posted on 2023-08-10
3177 ccTCM: a quantitative component and compound platform for promoting the research of traditional Chinese medicine
Yang, D.; Zhu, Z.; Yao, Q.; Chen, C.; Chen, F.; Gu, L.; Jiang, Y.; Chen, L.; Zhang, J.; Wu, J.; Gao, X.; Wang, J.; Li, G.; Zhao, Y.
10.1101/2023.08.04.551143 — bioinformatics — Posted on 2023-08-10
3178 Wistar rats raised in an affectionate environment display lifesaving-like behaviors while distinguishing life from death
Mikami, K.; Kigami, Y.; Doi, T.; Choudhury, M. E.; Nishikawa, Y.; Takahashi, R.; Wada, Y.; Kakine, H.; Kawase, M.; Hiyama, N.; Yano, H.; Abe, N.; Yorozuya, T.; Nishihara, T.; Tanaka, J.
10.1101/2023.08.08.552239 — animal behavior and cognition — Posted on 2023-08-09
3181 Three dimensional fibrotic extracellular matrix directs microenvironment fiber remodeling by fibroblasts
Nizamoglu, M.; Alleblas, F.; Koster, T.; Borghuis, T.; Vonk, J. M.; Thomas, M. J.; White, E. S.; Kirstin Watson, C.; Timens, W.; El Kasmi, K. C.; Melgert, B. N.; Heijink, I. H.; Burgess, J. K.
10.1101/2023.08.09.552411 — pathology — Posted on 2023-08-09
3184 Molecular dissection of the soluble photosynthetic antenna from a cryptophyte alga
Rathbone, H. W.; Laos, A. J.; Michie, K. A.; Iranmanesh, H.; Biazik, J.; Goodchild, S.; Thordarson, P.; Green, B. R.; Curmi, P. M.
10.1101/2023.08.08.552318 — molecular biology — Posted on 2023-08-09
3185 MET functions in tumour progression and therapy resistance are repressed by intronic polyadenylation
Boldina, G.; Vallejos, M.; Allard, D.; Cadix, M.; Labbe, C.; Vacher, S.; Hemmingsson, O.; Gestraud, P.; Teissandier, A.; Martineau, S.; Auboeuf, D.; Andre, F.; Kamal, M.; Servant, N.; Bieche, I.; Dutertre, M.; Robert, C.; Vagner, S.
10.1101/2023.08.09.552237 — molecular biology — Posted on 2023-08-09
3186 Prosaposin maintains adult neural stem cells in a state associated with deep quiescence
Labusch, M.; Thetiot, M.; Than-Trong, E.; Morizet, D.; Coolen, M.; Varet, H.; Legendre, R.; Ortica, S.; Mancini, L.; Bally-Cuif, L.
10.1101/2023.08.08.552453 — neuroscience — Posted on 2023-08-09
3187 Cell-type-specific plasticity shapes neocortical dynamics for motor learning
Majumder, S.; Hirokawa, K.; Yang, Z.; Gerfen, C. R.; Fontolan, L.; Romani, S.; Jain, A.; Yasuda, R.; Inagaki, H. K.
10.1101/2023.08.09.552699 — neuroscience — Posted on 2023-08-09
3194 Genomic and epidemiological evidence for the emergence of a putative L. donovani/L. infantum hybrid with unusual epidemiology in Northern Italy
Bruno, F.; Castelli, G.; Li, B.; Reale, S.; Carra, E.; Vitale, F.; Scibetta, S.; Calzolari, M.; Varani, S.; Ortalli, M.; Franceschini, E.; Gennari, W.; Rugna, G.; Spaeth, G. F.
10.1101/2023.08.09.552585 — genomics — Posted on 2023-08-09
3195 BirT: a novel primer pair for avian environmental DNA metabarcoding
Thalinger, B.; Empey, R.; Cowperthwaite, M.; Coveny, K.; Steinke, D.
10.1101/2023.08.08.552521 — molecular biology — Posted on 2023-08-09
3196 Synthetic rescue of XPC phenotype via PIK3C3 downregulation
KOBAISI, F.; SULPICE, E.; NASRALLAH, A.; FAYYAD-KAZAN, H.; RACHIDI, W.; GIDROL, X.
10.1101/2023.08.08.552431 — molecular biology — Posted on 2023-08-09
3198 ISWI1 complex proteins facilitate developmental genome editing in Paramecium
Singh, A.; Häussermann, L.; Emmerich, C.; Nischwitz, E.; Seah, B. K.; Butter, F. K. B.; Nowacki, M.; Swart, E. C.
10.1101/2023.08.09.552620 — molecular biology — Posted on 2023-08-09
3199 The endosomal sorting complex Retromer has a central role insystemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
van de Sluis, B.; Barbosa, M. G.; Heida, A. H.; Rios-Ocampo, W. A.; Tissink, J. J.; Koster, M. H.; Smit, M.; Huijkman, N.; Kloosterhuis, N. J.; Havinga, R.; Fuh, M. M.; Jonker, J. W.; Reggiori, F.; Mari, M.; Scheja, L.; Heeren, J.; Kuipers, F.; de Boer, J. F.; Wolters, J. C.; Kuivenhoven, J. A.; Vos, D. Y.
10.1101/2023.08.09.552611 — molecular biology — Posted on 2023-08-09
3200 ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease
Yanagi, T.; Kikuchi, H.; Takeuchi, K.; Susa, K.; Mori, T.; Takahashi, N.; Suzuki, T.; Nakano, Y.; Fujiki, T.; Hara, Y.; Suzuki, S.; Mori, Y.; Ando, F.; Mandai, S.; Honda, S.; Torii, S.; Shimizu, S.; Rai, T.; Uchida, S.; Sohara, E.
10.1101/2023.08.09.552390 — molecular biology — Posted on 2023-08-09
3202 CrWRKY42 positively regulates chlorophyll degradation and carotenoid biosynthesis in citrus
Chen, H.; Ji, H.; Huang, W.; Zhang, Z.; Zhu, K.; Zhu, S.; Chai, L.; Ye, J.; Deng, X.
10.1101/2023.08.09.552702 — molecular biology — Posted on 2023-08-09
3204 Folded alpha helical putative new proteins from Apilactobacillus kunkeei
Ye, W.; Behra, P. R. K.; Dyrhage, K.; Seeger, C.; Joiner, J. D.; Karlsson, E.; Andersson, E.; Chi, C.; Andersson, S. G.; Jemth, P.
10.1101/2023.08.08.552426 — molecular biology — Posted on 2023-08-09
3207 Hyphal exploration strategies and habitat modification of an arbuscular mycorrhizal fungus in microengineered soil chips
Hammer, E. C.; Arellano-Caicedo, C. G.; Mafla-Endara, P. M.; Kiers, E. T.; Shimizu, T.; Ohlsson, P.; Kadish, K. A.
10.1101/2023.08.09.552683 — microbiology — Posted on 2023-08-09
3208 Fecal microbiomes of laboratory beagles receiving antiparasitic formulations in an experimental setting
Ottesen, A.; Kocurek, B. J.; Deaver, C.; Chiesa, O.; Cohen, R.; Mammel, M. K.; Reed, E.; McDermott, P. F.; Strain, E. A.; Myers, M.
10.1101/2023.08.08.552529 — microbiology — Posted on 2023-08-09
3209 Phagocyte-expressed glycosaminoglycans promote capture of alphaviruses from the blood circulation in a host species-specific manner.
Ander, S. E.; Parks, M. G.; Davenport, B. J.; Li, F. S.; Bosco-Lauth, A.; Carpentier, K. S.; Sun, C.; Lucas, C. J.; Klimstra, W. B.; Ebel, G. D.; Morrison, T. E.
10.1101/2023.08.09.552690 — microbiology — Posted on 2023-08-09
3210 The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model
Ruelas Castillo, J.; Neupane, P.; Karanika, S.; Krug, S.; Quijada, D.; Garcia, A.; Ayeh, S.; Costa, D. L.; Sher, A.; Fotouhi, N.; Serbina, N.; Karakousis, P. C.
10.1101/2023.08.09.552716 — microbiology — Posted on 2023-08-09
3211 Machine-guided design of synthetic cell type-specific cis-regulatory elements
Gosai, S. J.; Castro, R. I.; Fuentes, N.; Butts, J. C.; Kales, S.; Noche, R. R.; Mouri, K.; Sabeti, P. C.; Reilly, S. K.; Tewhey, R.
10.1101/2023.08.08.552077 — synthetic biology — Posted on 2023-08-09
3212 Sex Differences in Human Music Perception are Negligible
Bertolo, M.; Müllensiefen, D.; Peretz, I.; Woolley, S. C.; Sakata, J.; Mehr, S.
10.1101/2023.05.23.541970 — animal behavior and cognition — Posted on 2023-08-09
3216 Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation
Fuchs Whightman, F.; Lukin, J.; Giusti, S.; Soutschek, M.; Bragado, L.; Pozzi, B.; Gonzalez, P.; Fededa, J. P.; Schratt, G.; Fujiwara, R.; Wilusz, J. E.; Refojo, D.; de la Mata, M.
10.1101/2022.04.11.487822 — molecular biology — Posted on 2023-08-09
3217 High-efficiency transformation and expression of genomic libraries in yeast
Loock, M.; Antunes, L. B.; Heslop, R. T.; De Lauri, A. A.; Lira, A. B.; Cestari, I.
10.1101/2023.08.07.552314 — molecular biology — Posted on 2023-08-09
3219 Neurophysiological trajectories in Alzheimer's disease progression
Kudo, K.; Ranasinghe, K. G.; Morise, H.; Syed, F.; Sekihara, K.; Rankin, K. P.; Miller, B. L.; Kramer, J.; Rabinovici, G.; Vossel, K.; Kirsch, H. E.; Nagarajan, S.
10.1101/2023.05.18.541379 — neuroscience — Posted on 2023-08-09
3221 TGF-β Ligand Cross-Subfamily Interactions in the Response of Caenorhabditis elegans to Bacterial Pathogens
Ciccarelli, E. J.; Wing, Z.; Bendelstein, M.; Johal, R. K.; Singh, G.; Monas, A.; Savage-Dunn, C.
10.1101/2023.05.05.539606 — physiology — Posted on 2023-08-09
3222 Saliva proteome-wide structural changes are associated with oral cancer aggressiveness
Granato, D. C.; Normando, A. G. C.; Carnielli, C. M.; Trino, L. D.; Busso-Lopes, A. F.; Camara, G. A.; Filho, H. V.; Domingues, R. R.; Yokoo, S.; Pauletti, B. A.; Patroni, F. M.; Santos-Silva, A. R.; Lopes, M. A.; Brandao, T.; Prado-Ribeiro, A. C.; de Oliveira, P. S.; Telles, G. P.; Paes Leme, A. F.
10.1101/2023.08.04.552034 — cancer biology — Posted on 2023-08-09
3223 Characterization of m6A modifiers and RNA modifications in uterine fibroids
George, J. W.; Cancino, R.; Miller, J. L. G.; Qiu, F.; Lin, Q.; Rowley, J.; Chennathukuzhi, V.; Davis, J. S.
10.1101/2023.08.07.552278 — cancer biology — Posted on 2023-08-09
3225 Comprehensive Structural Variant Detection: From Mosaic to Population-Level
Smolka, M.; Paulin, L. F.; Grochowski, C. M.; Horner, D. W.; Mahmoud, M.; Behera, S.; Kalef-Ezra, E.; Gandhi, M.; Hong, K.; Pehlivan, D.; Scholz, S. W.; Carvalho, C. M.; Proukakis, C.; Sedlazeck, F. J.
10.1101/2022.04.04.487055 — bioinformatics — Posted on 2023-08-09
3226 Environment and taxonomy shape the genomic signature of prokaryotic extremophiles
Millan Arias, P.; Butler, J.; Randhawa, G. S.; Soltysiak, M. P. M.; Hill, K. A.; Kari, L.
10.1101/2023.05.24.542097 — bioinformatics — Posted on 2023-08-09
3227 ccTCM: a quantitative component and compound platform for promoting the research of traditional Chinese medicine
Yang, D.; Zhu, Z.; Yao, Q.; Chen, C.; Chen, F.; Gu, L.; Jiang, Y.; Chen, L.; Zhang, J.; Wu, J.; Gao, X.; Wang, J.; Li, G.; Zhao, Y.
10.1101/2023.08.04.551143 — bioinformatics — Posted on 2023-08-09
3229 An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants
Nmezi, B.; Bey, G. R.; Oranburg, T. D.; Dudnyk, K.; Lardo, S. M.; Herdman, N.; Jacko, A.; Rubio, S.; Alcocer, E. L.; Kofler, J.; Kim, D.; Rankin, J.; Kivuva, E.; Gutowski, N.; Schon, K.; van den Ameele, J.; Chinnery, P. F.; Sousa, S. B.; Palavra, F.; Toro, C.; Pinto e Vairo, F.; Saute, J.; Pan, L.; Alturkustani, M.; Hammond, R.; Gros-Louis, F.; Gold, M.; Park, Y.; Bernard, G.; Raininko, R.; Zhou, J.; Hainer, S. J.; Padiath, Q.
10.1101/2023.08.03.551473 — genetics — Posted on 2023-08-09
3230 Positive selection in gamete interaction proteins in Carnivora
Pisciottano, F.; Campos, M. C.; Penna, C.; Bruque, C. D.; Gabaldon, T.; Saragueta, P.
10.1101/2022.03.22.485370 — evolutionary biology — Posted on 2023-08-09
3231 Human induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation
Piechota, S.; Marchante, M.; Giovannini, A.; Paulsen, B.; Potts, K. S.; Rockwell, G.; Aschenberger, C.; Noblett, A. D.; Figueroa, A. B.; Sanchez, M.; Barrachina, F.; Wiemer, K.; Guzman, L.; Belchin, P.; Pierson Smela, M.; Fortuna, P. R.; Chatterjee, P.; Tran, N. D.; Kelk, D. A.; Forti, M.; Marcinyshyn, S.; Smith, T.; McCulloh, D. H.; Fernandez-Gonzalez, M.-J.; Ortiz, S.; Klein, J.; Klatsky, P.; Ordonez-Perez, D.; Kramme, C. C.
10.1101/2023.03.27.534479 — developmental biology — Posted on 2023-08-09
3233 Delivery of loaded MR1 Monomer Results in Efficient Ligand Exchange to Host MR1 and Subsequent MR1T cell activation
Kulicke, C. A.; Swarbrick, G. M.; Ladd, N. A.; Cansler, M.; Null, M.; Worley, A.; Lemon, C.; Ahmed, T.; Bennett, J.; Lust, T. N.; Heisler, C. M.; Huber, M. E.; Krawic, J. R.; Ankley, L. M.; McBride, S. K.; Tafesse, F. G.; Olive, A.; Hildebrand, W. H.; Lewinsohn, D. A.; Adams, E. J.; Lewinsohn, D. M.; Harriff, M. J.
10.1101/2022.07.11.499573 — immunology — Posted on 2023-08-09
3235 Inflammation causes insulin resistance via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels
Yan, S.; Santoro, A.; Niphakis, M. J.; Pinto, A. M.; Jacobs, C. L.; Ahmad, R.; Suciu, R. M.; Fonslow, B. R.; Herbst-Graham, R. B.; Ngo, N.; Henry, C. L.; Herbst, D. M.; Saghatelian, A.; Kahn, B. B.; Rosen, E. D.
10.1101/2023.08.08.552481 — physiology — Posted on 2023-08-09
3237 Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure
Bullert, A.; Li, X.; Zhang, C.; Lee, K.; Pulliam, C. F.; Cagle, B. S.; Doorn, J. A.; Klingelhutz, A. J.; Robertson, L. W.; Lehmler, H.-J.
10.1101/2023.06.19.544952 — pharmacology and toxicology — Posted on 2023-08-09
3245 Mu-opioid receptor-dependent changes in social reward across adolescence in mice
Harda, Z.; Klimczak, M.; Misiolek, K.; Chroszcz, M.; Szumiec, L.; Jarosz, M. K.; Rygula, R.; Ziolkowska, B.; Parkitna, J. R.
10.1101/2023.07.19.549691 — neuroscience — Posted on 2023-08-09
3246 Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation
Elkholi, I. E.; Robert, A.; Kuasne, H.; Drapela, S.; Macleod, G.; Hebert, S.; Pacis, A.; Calderon, V.; Kleinman, C. L.; Gomes, A. P.; Aguirre-Ghiso, J. A.; Park, M.; Angers, S.; Cote, J.-F.
10.1101/2023.08.02.551681 — cancer biology — Posted on 2023-08-09
3248 Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the involvement of free mitochondrial DNA and therapeutic effects of endothelial exosomes
Lu, X. Z.; Rafatian, N.; Zhao, Y.; Wagner, K. T.; Beroncal, E. L.; Li, B.; Lee, C.; Chen, J.; Churcher, E.; Vosoughi, D.; Wang, Y.; Baker, A.; Trahtemberg, U.; Li, B.; Pierro, A.; Andreazza, A.; dos Santos, C. C.; Radisic, M.
10.1101/2023.08.09.552495 — bioengineering — Posted on 2023-08-09
3251 A conserved ribosomal protein has entirely dissimilar structures in different organisms
Schierholz, L.; Brown, C. R.; Helena-Bueno, K.; Uversky, V. N.; Hirt, R.; Barandun, J.; Melnikov, S. V.
10.1101/2022.09.21.508910 — evolutionary biology — Posted on 2023-08-09
3252 pADP-ribosylation Regulates the Cytoplasmic Localization, Cleavage and Pro-apoptotic Function of HuR
Ashour, K.; Hall, D. T.; Mubaid, S.; Bousque, S.; Lian, X.; Gagne, J.-P.; Khattak, S.; Di Marco, S.; Poirier, G.; Gallouzi, I. E.
10.1101/2023.08.07.552262 — cell biology — Posted on 2023-08-09
3253 Microglial cGAS deletion protects against amyloid-β induced Alzheimer's disease pathogenesis
He, S.; Li, X.; Mittra, N.; Bhattacharjee, A.; Wang, H.; Zhao, S.; Liu, F.; Han, X.
10.1101/2023.08.07.552300 — neuroscience — Posted on 2023-08-09
3254 Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation
Lee, C. Y.; Hubrich, D.; Varga, J. K.; Schäfer, C.; Welzel, M.; Schumbera, E.; Đokic, M.; Strom, J. M.; Schönfeld, J.; Geist, J. L.; Polat, F.; Gibson, T. J.; Keller Valsecchi, C. I.; Kumar, M.; Schueler-Furman, O.; Luck, K.
10.1101/2023.08.07.552219 — systems biology — Posted on 2023-08-09
3255 DeltaAI: Semi-Autonomous Tissue Grossing Measurements and Recommendations using Neural Radiance Fields for Rapid, Complete Intraoperative Histological Assessment of Tumor Margins
Suvarna, A.; Vempati, R.; Chacko, R.; Srinivasan, G.; Lu, Y.; Hunt, B.; Torres, V.; Samkoe, K.; Davis, M.; Fu, L.; Christensen, B.; Vaickus, L.; LeBoeuf, M.; Levy, J.
10.1101/2023.08.07.552349 — pathology — Posted on 2023-08-09
3257 iMOUSE - Reforming the Strategy of Refinement and Reduction for indispensable laboratory animal-based studies in translational research
Łaz, M.; Lampe, M.; Connor, I.; Shestachuk, D.; Ludwig, M.; Suendermann, N.; Mueller, U.; Strauch, O.; Lüth, S.; Kah, J.
10.1101/2023.08.06.552188 — animal behavior and cognition — Posted on 2023-08-09
3258 Cellular hnRNPA0 limits HIV-1 production by interference with LTR-activity and programmed ribosomal frame-shifting
Roesmann, F.; Sertznig, H.; Klaassen, K.; Wilhelm, A.; Heininger, D.; Elsner, C.; Santiago, M. L.; Esser, S.; Sutter, K.; Dittmer, U.; Widera, M.
10.1101/2023.08.08.552510 — microbiology — Posted on 2023-08-09
3259 The stromal side of cytochrome b6f complex regulates state transitions
Riche, A.; Dumas, L.; Malesinski, S.; Bossan, G.; Madigou, C.; Zito, F.; Alric, J.
10.1101/2023.08.08.552398 — plant biology — Posted on 2023-08-09
3260 Molecular portraits of colorectal cancer morphological regions
Budinska, E.; Hrivnakova, M.; Catela Ivkovic, T.; Madrzyk, M.; Nenutil, R.; Bencsikova, B.; Al Tukmachi, D.; Ruckova, M.; Zdrazilova Dubska, L.; Slaby, O.; Feit, J.; Dragomir, M.-P.; Borilova Linhartova, P.; Tejpar, S.; Popovici, V.
10.1101/2023.01.24.525310 — cancer biology — Posted on 2023-08-09
3265 Crystal ribcage: a platform for probing real-time lung function at cellular resolution in health and disease
Banerji, R.; Grifno, G. N.; Shi, L.; Smolen, D.; LeBourdais, R.; Muhvich, J.; Eberman, C.; Hiller, B.; Lee, J.; Regan, K.; Zheng, S.; Zhang, S. S.; Jiang, J.; Raslan, A. A.; Breda, J. C.; Pihl, R.; Traber, K.; Mazzilli, S.; Ligresti, G.; Mizgerd, J. P.; Suki, B.; Nia, H. T.
10.1101/2022.10.28.514251 — bioengineering — Posted on 2023-08-09
3266 A strict requirement in proteasome substrates for spacing between ubiquitin tag and degradation initiation elements
Davis, C.; Spaller, B. L.; Choi, E.; Kurrasch, J. B.; Chong, H.; Elsasser, S.; Finley, D.; Matouschek, A.
10.1101/2023.08.08.552540 — biochemistry — Posted on 2023-08-09
3270 TMEM165 acts as a proton-activated Ca2+ importer in lysosomes
Zajac, M.; Mukherjee, S.; Anees, P.; Oettinger, D.; Henn, K.; Srikumar, J.; Zou, J.; Saminathan, A.; Krishnan, Y.
10.1101/2023.08.08.552438 — cell biology — Posted on 2023-08-09
3271 A bacterial sialidase mediates early life colonization by a pioneering gut commensal
Buzun, E.; Hsu, C.-Y.; Sejane, K.; Oles, R. E.; Ayala, A. V.; Loomis, L. R.; Zhao, J.; Rossitto, L.-A.; McGrosso, D.; Gonzalez, D. J.; Bode, L.; Chu, H.
10.1101/2023.08.08.552477 — microbiology — Posted on 2023-08-09
3272 Algal CO2 capture is powered by alternative electron pathways of photosynthesis
Peltier, G.; Stoffel, C.; Findinier, J.; Madireddi, S. K.; Dao, O.; Epting, V.; Grossman, A.; Li-Beisson, Y.; Burlacot, A.
10.1101/2023.08.08.552514 — plant biology — Posted on 2023-08-09
3274 dGAE(297-391) tau fragment promotes formation of CTE-like full-length tau filaments
Kitoka, K.; Lends, A.; Kucinskas, G.; Bula, A. L.; Krasauskas, L.; Smirnovas, V.; Zilkova, M.; Kovacech, B.; Skrabana, R.; Hritz, J.; Jaudzems, K.
10.1101/2023.02.01.526268 — biophysics — Posted on 2023-08-09
3276 The Hedgehog receptors PTCH1 and PTCH2 exist as active homomeric and heteromeric complexes
Timmis, A. J.; Cross, F.; Gkotsi, D. S.; Ollerton, H.; Johnson, C. A.; Riobo-Del Galdo, N. A.
10.1101/2023.08.08.549832 — biochemistry — Posted on 2023-08-09
3278 Akr1b7 functions as a master regulator in ovarian aging
Isayama, K.; Watanabe, K.; Ohtsuka, M.; Kimura, S.; Murata, T.; Honda, T.; Asagiri, M.; Sato, S.; Tamura, H.; Sugino, N.; Mizukami, Y.
10.1101/2023.08.09.552567 — molecular biology — Posted on 2023-08-09
3279 Interaction of PINK1 with nucleotides and kinetin
Gan, Z. Y.; Callegari, S.; Nguyen, T. N.; Kirk, N. S.; Leis, A.; Lazarou, M.; Dewson, G.; Komander, D.
10.1101/2023.08.08.552531 — molecular biology — Posted on 2023-08-09
3281 Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases
Betancurt-Anzola, L.; Martinez-Carranza, M.; Delarue, M.; Zatopek, K.; Gardner, A.; Sauguet, L.
10.1101/2023.08.09.552591 — molecular biology — Posted on 2023-08-09
3283 The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species.
Xie, J.; Rybak, J.; Martin-Vicente, A.; Guruceaga, X.; Thorn, H.; Nywening, A.; Ge, W.; Parker, J.; Kelly, S. L.; Rogers, D.; Fortwendel, J.
10.1101/2023.08.08.552489 — microbiology — Posted on 2023-08-09
3284 Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
Corrales, J.; Ramos-Alonso, L.; Gonzalez-Sabin, J.; Rios-Lombardia, N.; Trevijano-Contador, N.; Engen Berg, H.; Sved Skottvoll, F.; Moris, F.; Zaragoza, O.; Chymkowitch, P.; Garcia, I.; Enserink, J.
10.1101/2023.08.09.552590 — microbiology — Posted on 2023-08-09
3285 Deep learning-based image analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra.
Burkert, N.; Roy, S.; Haeusler, M.; Wuttke, D.; Mueller, S.; Wiemer, J.; Hollmann, H.; Oldrati, M.; Ramirez-Franco, J.; Benkert, J.; Fauler, M.; Duda, J.; Goaillard, J.-M.; Poetschke, C.; Muenchmeyer, M.; Parlato, R.; Liss, B.
10.1101/2022.12.14.520432 — neuroscience — Posted on 2023-08-09
3286 Xylem sap residue in cut-open conduits can affect gas discharge in pneumatic experiments
Miranda, M. T.; Pereira, L.; Pires, G. S.; Guan, X.; Silva, L. M.; Kreinert, S.; Machado, E. C.; Jansen, S.; Ribeiro, R.
10.1101/2023.08.08.552466 — plant biology — Posted on 2023-08-09
3288 The HuMet Repository: Watching human metabolism at work
Weinisch, P.; Raffler, J.; Römisch-Margl, W.; Arnold, M.; Mohney, R. P.; Rist, M. J.; Prehn, C.; Skurk, T.; Hauner, H.; Daniel, H.; Suhre, K.; Kastenmüller, G.
10.1101/2023.08.08.550079 — biochemistry — Posted on 2023-08-09
3290 A novel PEX14/PEX5 interface links peroxisomal protein import and receptor recycling
Emmanouilidies, L.; Sehr, J.; Reglinski, K.; Gaussmann, S.; Goricanec, D.; Kordon, J.; Menezes, F.; Waithe, D.; Hublitz, P.; Bader, V.; Winklhofer, K. F.; Jung, M.; Schliebs, W.; Eggeling, C.; Erdmann, R.; Sattler, M.
10.1101/2023.08.08.552478 — biochemistry — Posted on 2023-08-09
3291 Phenotypic variation in maize can be largely explained by genetic variation at transcription factor binding sites
Engelhorn, J.; Snodgrass, S. J.; Kok, A.; Seetharam, A. S.; Schneider, M.; Kiwit, T.; Singh, A.; Banf, M.; Khaipho-Burch, M.; Runcie, D. E.; Camargo, V. S.; Torres-Rodriguez, J. V.; Sun, G.; Stam, M.; Fiorani, F.; Schnable, J. C.; Bass, H. W.; Hufford, M. B.; Stich, B.; Frommer, W. B.; Ross-Ibarra, J.; Hartwig, T.
10.1101/2023.08.08.551183 — genomics — Posted on 2023-08-09
3293 North American Powassan virus encompasses diverse in vitro phenotypes.
McMinn, R. J.; Langsjoen, R. M.; Normandin, E. J.; Stampfer, S. D.; Sabeti, P. C.; Piantadosi, A.; Ebel, G. D.
10.1101/2023.08.08.552515 — microbiology — Posted on 2023-08-09
3297 Comparative Analysis, Diversification and Functional Validation of Plant Nucleotide-Binding Site Domain Genes
Hussain, A.; Khan, A. A.; Aslam, M. Q.; Nazar, A.; Zaman, N.; Amin, A.; Mahmood, M. A.; Mukhtar, M. S.; Rahman, H. U. U.; Farooq, M.; Saeed, M.; Amin, I.; Mansoor, S.
10.1101/2023.08.09.552572 — plant biology — Posted on 2023-08-09
3299 Molecular mechanisms of microbiome modulation by the eukaryotic secondary metabolite azelaic acid
Shibl, A. A.; Ochsenkuhn, M. A.; Mohamed, A. R.; Isaac, A.; Coe, L. S. Y.; Yun, Y.; Skrzypek, G.; Raina, J.-B.; Seymour, J. R.; Afzal, A. J.; Amin, S. A.
10.1101/2022.04.08.487398 — ecology — Posted on 2023-08-09
3301 Two gustatory receptors involved in host plant recognition of silkworm larvae
Endo, H.; Tsuneto, K.; Yamagishi, T.; Dingze, M.; Ito, K.; Nagata, S.; Sato, R.
10.1101/2022.09.12.507514 — neuroscience — Posted on 2023-08-09
3306 PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES
Noto, A.; Valenzisi, P.; Fratini, F.; Kulikowicz, T.; Sommers, J. A.; Di Feo, F.; Palermo, V.; Semproni, M.; Crescenzi, M.; Brosh, R. M.; Franchitto, A.; Pichierri, P.
10.1101/2023.08.08.552428 — cell biology — Posted on 2023-08-09
3307 Autophagy preferentially degrades non-fibrillar polyQ aggregates
Zhao, D. Y.; Bauerlein, F. J.; Saha, I.; Hartl, F.-U.; Baumeister, W.; Wilfling, F.
10.1101/2023.08.08.552291 — cell biology — Posted on 2023-08-09
3312 The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in atrophic AMD
Ghosh, S.; Sharma, R.; Bammidi, S.; Koontz, V.; Nemani, M.; Yazdankhah, M.; Kedziora, K. M.; Wallace, C. T.; Yu-Wei, C.; Franks, J.; Bose, D.; Rajasundaram, D.; Hose, S.; Sahel, J.-A.; Puertollano, R.; Finkel, T.; Zigler, J. S.; Sergeev, Y.; Watkins, S. C.; Goetzman, E. S.; Flores-Bellver, M.; Kaarniranta, K.; Sodhi, A.; Bharti, K.; Handa, J. T.; Sinha, D.
10.1101/2023.08.08.552343 — cell biology — Posted on 2023-08-09
3313 Multi-scale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma
Ganier, C.; Mazin, P.; Herrera-Oropeza, G.; Du-Harpur, X.; Blakeley, M.; Gabriel, J.; Predeus, A.; Cakir, B.; Prete, M.; Harun, N.; Darrigrand, J.-F.; Haiser, A.; Wyles, S.; Shaw, T. J.; Teichmann, S. A.; Haniffa, M.; Watt, F. M.; Lynch, M. D.
10.1101/2023.08.08.551504 — cell biology — Posted on 2023-08-09
3314 TMEM165 acts as a proton-activated Ca2+ importer in lysosomes
Zajac, M.; Mukherjee, S.; Anees, P.; Oettinger, D.; Henn, K.; Srikumar, J.; Zou, J.; Saminathan, A.; Krishnan, Y.
10.1101/2023.08.08.552438 — cell biology — Posted on 2023-08-09
3315 Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets
Somuncular, E.; Hauenstein, J.; Su, T.-Y.; Dumral, O.; Gustafsson, C.; Tzortzis, E.; Forlani, A.; Johansson, A.-S.; Mansson, R.; Luc, S.
10.1101/2023.08.08.552444 — cell biology — Posted on 2023-08-09
3319 Lateral Septal Circuits Govern Schizophrenic-Like Effects of Ketamine on Social Behavior
Wang, R.; Peterson, Z. J.; Balasubramanian, N.; Khan, K. M.; Chimenti, M. S.; Thedens, D.; Nickl-Jockschat, T.; Marcinkiewcz, C.
10.1101/2023.08.08.552372 — neuroscience — Posted on 2023-08-08
3320 Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina.
Lyu, P.; Iribarne, M.; Serjanov, D.; Zhai, Y.; Hoang, T.; Campbell, L.; Boyd, P.; Palazzo, I.; Nagashima, M.; Silva, N. J.; Hitchcock, P.; Qian, J.; Hyde, D.; Blackshaw, S.
10.1101/2023.08.08.552451 — neuroscience — Posted on 2023-08-08
3321 ERK signaling drives evolutionary expansion of the mammalian cerebral cortex
Sun, M.; Gao, Y.; Li, Z.; Yang, L.; Liu, G.; Xu, Z.; Guo, R.; You, Y.; Yang, Z.
10.1101/2023.08.08.552393 — neuroscience — Posted on 2023-08-08
3322 Performing highly parallelized and reproducible GWAS analysis on biobank-scale data
Schoenherr, S.; Schachtl-Riess, J.; Di Maio, S.; Filosi, M.; Mark, M.; Lamina, C.; Fuchsberger, C.; Kronenberg, F.; Forer, L.
10.1101/2023.08.08.552417 — bioinformatics — Posted on 2023-08-08
3324 ATRX guards against aberrant differentiation in mesenchymal progenitor cells
Fang, Y.; Barrows, D.; Dabas, Y.; Carroll, T. S.; Tap, W. D.; Nacev, B.
10.1101/2023.08.08.552433 — genetics — Posted on 2023-08-08
3326 NVX-CoV2373 ancestral and NVX-CoV2540 BA.5 protein nanoparticle vaccines protect against Omicron BA.5 variant in Syrian hamsters
Bricker, T. L.; Joshi, A.; Soudani, N.; Scheaffer, S.; Patel, N.; Xabier, M. G.; Smith, G.; Diamond, M.; Boon, A. C.
10.1101/2023.08.07.552330 — microbiology — Posted on 2023-08-08
3328 Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity
Zheng, Q.; Bastle, R. M.; Zhao, S.; Kong, L.; Vostal, L.; Ramakrishnan, A.; Shen, L.; Fulton, S. L.; Wang, H.; Zhang, B.; Upad, A.; Dierdorff, L.; Thompson, R. E.; Molina, H.; Stransky, S.; Sidoli, S.; Muir, T. W.; Li, H.; David, Y.; Maze, I.
10.1101/2022.12.06.519310 — molecular biology — Posted on 2023-08-08
3329 Antiviral efficacy of the SARS-CoV-2 XBB breakthrough infection sera against Omicron subvariants including EG.5
Kaku, Y.; Kosugi, Y.; Uriu, K.; Ito, J.; Kuramochi, J.; Sadamasu, K.; Yoshimura, K.; Asakura, H.; Nagashima, M.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Sato, K.
10.1101/2023.08.08.552415 — microbiology — Posted on 2023-08-08
3331 Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-headed tortoise (Indotestudo elongata (Blyth, 1854))
Bochaton, C.; Chantasri, S.; Maneechote, M.; Claude, J.; Griggo, C.; Naksri, W.; Forestier, H.; Sophady, H.; Auertrakulvit, P.; Bowonsachoti, J.; Zeitoun, V.
10.1101/2023.04.27.538552 — paleontology — Posted on 2023-08-08
3332 MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis
Cazarin, J.; DeRollo, R. E.; Ahmad Shahidan, S. N. A. B.; Burchett, J. B.; Mwangi, D.; Krishnaiah, S.; Hsieh, A. L.; Walton, Z. E.; Brooks, R.; Mello, S. S.; Weljie, A. M.; Dang, C. V.; Altman, B. J.
10.1101/2023.01.03.522637 — cancer biology — Posted on 2023-08-08
3333 The landscape of drug sensitivity and resistance in sarcoma
Al Shihabi, A.; Tebon, P. J.; Nguyen, H. T. L.; Chantharasamee, J.; Sartini, S.; Davarifar, A.; Jensen, A. Y.; Diaz-Infante, M.; Cox, H.; Enrique-Gonzalez, A.; Swearingen, S.; Tavanaie, N.; Dry, S.; Singh, A.; Chmielowski, B.; Crompton, J. G.; Kalbasi, A.; Eilber, F. C.; Hornicek, F.; Bernthal, N.; Nelson, S. D.; Boutros, P. C.; Federman, N.; Yanagawa, J.; Soragni, A.
10.1101/2023.05.25.542375 — cancer biology — Posted on 2023-08-08
3337 Detecting co-selection through excess linkage disequilibrium in bacterial genomes
Mallawaarachchi, S.; Tonkin-Hill, G.; Pöntinen, A. K.; Calland, J. K.; Gladstone, R. A.; Arredondo-Alonso, S.; MacAlasdair, N.; Thorpe, H. A.; Top, J.; Sheppard, S. K.; Balding, D.; Croucher, N. J.; Corander, J.
10.1101/2023.08.04.551407 — bioinformatics — Posted on 2023-08-08
3340 Glial-derived mitochondrial signals impact neuronal proteostasis and aging.
Bar-Ziv, R.; Dutta, N.; Hruby, A.; Sukarto, E.; Henderson, H. R.; Durieux, J.; Tronnes, S. U.; Averbukh, M.; Alcala, A.; Ahmad, Q.; Bolas, T.; Perez, J.; Dishart, J. G.; Vega, M.; Garcia, G.; Higuchi-Sanabria, R.; Dillin, A.
10.1101/2023.07.20.549924 — genetics — Posted on 2023-08-08
3341 Genomic data suggest parallel dental vestigialization within the xenarthran radiation
Emerling, C. A.; Gibb, G. C.; Tilak, M.-K.; Hughes, J. J.; Kuch, M.; Duggan, A. T.; Poinar, H. N.; Nachman, M. W.; Delsuc, F.
10.1101/2022.12.09.519446 — evolutionary biology — Posted on 2023-08-08
3342 Modeling individual variability in habitat selection and movement using integrated step-selection analyses
Chatterjee, N.; Wolfson, D.; Kim, D.; Gomez, J. V.; Freeman, S.; Bacheler, N. M.; Shertzer, K.; Taylor, C.; Fieberg, J.
10.1101/2023.07.31.551213 — ecology — Posted on 2023-08-08
3344 Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping
McCormack, N. M.; Calabrese, K. A.; Sun, C. M.; Tully, C. B.; Heier, C. R.; Fiorillo, A. A.
10.1101/2023.05.09.540042 — molecular biology — Posted on 2023-08-08
3346 Impact of Streptococcus pneumoniae biosynthesis gene mutations on epithelial microinvasion and cellular responses
Weight, C. M.; Pollara, G. M.; Betts, M.; Ragazzini, R.; Connor, M.; Ramos-Sevillano, E.; Reine, J.; Whelan, M.; Guerra-Assuncao, J. A.; Bonfanti, P.; Jolly, C.; Noursadeghi, M.; Ferreira, D.; Brown, J.; Heyderman, R. S.
10.1101/2023.06.15.545009 — microbiology — Posted on 2023-08-08
3348 Vimo: Visual Analysis of Neuronal Connectivity Motifs
Troidl, J.; Warchol, S.; Choi, J.; Matelsky, J.; Dhanysai, N.; Wang, X.; Wester, B.; Wei, D.; Lichtman, J. W.; Pfister, H.; Beyer, J.
10.1101/2022.12.09.519772 — neuroscience — Posted on 2023-08-08
3354 ProteoMixture: A Cell Type Deconvolution Tool for Bulk Tissue Proteomics Data
Teng, P.-n.; Schaaf, J. P.; Abulez, T.; Hood, B. L.; Wilson, K. N.; Litzi, T. J.; Conrads, K. A.; Hunt, A. L.; Olowu, V.; Oliver, J.; Park, F. S.; Edwards, M.; Chiang, A.; Raj-Kumar, P.-K.; Tarney, C. M.; Darcy, K. M.; Phippen, N. T.; Maxwell, G. L.; Conrads, T. P.; Bateman, N. W.
10.1101/2023.07.27.550810 — bioinformatics — Posted on 2023-08-08
3356 The shared ancestry between the C9orf72 hexanucleotide repeat expansion and intermediate-length alleles using haplotype sharing trees and HAPTK
Rautila, O. S.; Kaivola, K.; Rautila, H.; Hokkanen, L.; Launes, J.; Strandberg, T. E.; Laaksovirta, H.; Palmio, J.; Tienari, P. J.
10.1101/2023.07.28.550820 — genetics — Posted on 2023-08-08
3357 Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae
Le Naour--Vernet, M.; Charriat, F.; Gracy, J.; Cros-Arteil, S.; Ravel, S.; Veillet, F.; Meusnier, I.; Padilla, A.; Kroj, T.; Cesari, S.; Gladieux, P.
10.1101/2023.03.16.532886 — evolutionary biology — Posted on 2023-08-08
3359 Ablation of oligodendrogenesis in adult mice alters brain microstructure and activity independently of behavioural deficits
Kaller, M. S.; Lazari, A.; Feng, Y.; van der Toorn, A.; Ruehling, S.; Thomas, C. W.; Shimizu, T.; Bannerman, D. M.; Vyazovskiy, V.; Richardson, W. D.; Sampaio-Baptista, C.; Johansen-Berg, H.
10.1101/2023.07.06.547854 — neuroscience — Posted on 2023-08-08
3360 Pathogenic entero- and salivatypes harbour changes in microbiome virulence and antimicrobial resistance genes with increasing chronic liver disease severity
Lee, S.; Arefaine, B.; Begum, N.; Stamouli, M.; Witherden, E.; Mohamad, M.; Harzandi, A.; Zamalloa, A.; Cai, H.; Edwards, L. A.; Williams, R.; Chokshi, S.; Mardinoglu, A.; Proctor, G.; Shawcross, D. L.; Moyes, D.; Uhlen, M.; Shoaie, S.; Patel, V. C.
10.1101/2023.08.06.552152 — physiology — Posted on 2023-08-08
3361 Modelling human brain-wide pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits
Laguna, A.; Penuelas, N.; Gonzalez-Sepulveda, M.; Nicolau, A.; Arthaud, S.; Guilliard.Sirieix, C.; Lorente-Picon, M.; Compte, J.; Miquel-Rio, L.; Xicoy, H.; Liu, J.; Parent, A.; Cuadros, T.; Romero-Gimenez, J.; Pujol, G.; Gimenez-Llort, L.; Fort, P.; Bortolozzi, A.; Carballo-Carbajal, I.; Vila, M.
10.1101/2023.08.08.552400 — neuroscience — Posted on 2023-08-08
3362 Gene expression is the main driver of purifying selection in large penguin populations
Trucchi, E.; Massa, P.; Giannelli, F.; Fernandes, F. A. N.; Ancona, L.; Stenseth, N. C.; Ferrer Obiol, J.; Paris, J.; Bertorelle, G.; Le Bohec, C.
10.1101/2023.08.08.552445 — evolutionary biology — Posted on 2023-08-08
3363 The X-Linked Intellectual Disability gene, ZDHHC9, is important for oligodendrocyte maturation and myelin formation
Hollman, R. B.; Wild, A. R.; O'Leary, T. P.; Thompson, A. J.; Flibotte, S.; Poblete, T. O.; Peng, A.; Rogalski, J. C.; Gill, G.; Bamji, S. X.
10.1101/2023.08.08.552342 — neuroscience — Posted on 2023-08-08
3365 High-efficiency transformation and expression of genomic libraries in yeast
Loock, M.; Antunes, L. B.; Heslop, R. T.; De Lauri, A. A.; Lira, A. B.; Cestari, I.
10.1101/2023.08.07.552314 — molecular biology — Posted on 2023-08-08
3366 Unilateral ephaptic program underlying sweetness dominance
Lee, M.; Kim, S. Y.; Park, T.; Joo, K. M.; Kwon, J. Y.; Kim, K.; Kang, K.
10.1101/2023.08.04.551918 — neuroscience — Posted on 2023-08-08
3368 Mapping functional traces of opioid memories in the rat brain
Gomes-Ribeiro, J.; Martins, J.; Sereno, J.; Deslauriers, S.; Summavielle, T.; Coelho, J. E.; Remondes, M.; Castelo-Branco, M.; Lopes, L. V.
10.1101/2023.08.07.552221 — neuroscience — Posted on 2023-08-08
3370 Discovery of an isoflavone oxidative catabolic pathway in legume root microbiota
Aoki, N.; Shimasaki, T.; Yazaki, W.; Sato, T.; Nakayasu, M.; Ando, A.; Kishino, S.; Ogawa, J.; Masuda, S.; Shibata, A.; Shirasu, K.; Yazaki, K.; Sugiyama, A.
10.1101/2023.08.07.552369 — plant biology — Posted on 2023-08-08
3373 Crowdsourcing Temporal Transcriptomic Coronavirus Host Infection Data: resources, guide, and novel insights.
Flynn, J.; Ahmadi, M. M.; McFarland, C. T.; Kubal, M. D.; Taylor, M. A.; Cheng, Z.; Torchia, E. C.; Edwards, M. G.
10.1101/2022.12.14.520483 — bioinformatics — Posted on 2023-08-08
3374 Material Properties of Nonpregnant and Pregnant Human Uterine Layers
Fodera, D. M.; Russell, S. R.; Lund-Jackson, J. L.; Fang, S.; Vink, J.-S. Y.; Oyen, M. L.; Myers, K. M.
10.1101/2023.08.07.551726 — bioengineering — Posted on 2023-08-08
3383 Comparison of metabarcoding taxonomic markers to describe fungal communities in fermented foods
Rue, O.; Cotton, M.; Dugat-Bony, E.; Howell, K.; Irlinger, F.; Legras, J.-L.; Loux, V.; Michel, E.; Mounier, J.; Neuveglise, C.; Sicard, D.
10.1101/2023.01.13.523754 — microbiology — Posted on 2023-08-08
3386 Long-term plasticity induces sparse and specific synaptic changes in a biophysically detailed cortical model
Ecker, A.; Egas Santander, D.; Abdellah, M.; Blanco Alonso, J.; Bolanos-Puchet, S.; Chindemi, G.; Isbister, J. B.; King, J. G.; Kumbhar, P.; Magkanaris, I.; Muller, E. B.; Reimann, M. W.
10.1101/2023.08.07.552264 — neuroscience — Posted on 2023-08-08
3389 microRNA profile of endometrial cancer from Indian patients-Identification of potential biomarkers for prognosis
Hegde, S.; Wagh, K. A.; Abikar, A.; Nambiar, S.; Ananthamurthy, S.; Narayana, N. H.; Reddihalli, P. V.; Chandraiah, S.; Narayana, S. M.; Ranganathan, P.
10.1101/2023.08.07.552324 — cancer biology — Posted on 2023-08-08
3390 Vascularized tumor on a microfluidic chip to study mechanisms promoting tumor neovascularization and vascular targeted therapies
Skubal, M.; Mc Larney, B. E.; Phung, N. B.; Desmaras, J. C.; Dozic, A.-V.; Volpe, A.; Ogirala, A.; Machado, C. M. L.; Djibankov, J.; Ponomarev, V.; Grimm, J.
10.1101/2023.08.07.552309 — cancer biology — Posted on 2023-08-08
3391 A novel lncRNA PROCA11 regulates cell plasticity in response to androgen deprivation of prostate cancer cells
Cipolla, R.; Gabriel, M.; Regin, G. I.; Piemontese, M.; Szachnowski, U.; Firlej, V.; Pinskaya, M.; Morillon, A.
10.1101/2023.08.07.552355 — cancer biology — Posted on 2023-08-08
3392 Deep learning reduces data requirements and allows real-time measurements in Imaging Fluorescence Correlation Spectroscopy
Wohland, T.; Tang, W. H.; Sim, S. R.; Aik, D. Y. K.; Nelanuthala, A. V. S.; Athilingam, T.; Röllin, A.
10.1101/2023.08.07.552352 — biophysics — Posted on 2023-08-08
3393 Per-pixel unmixing of spectrally overlapping fluorophores using intra-exposure excitation modulation
Valenta, H.; Bierbuesse, F.; Vitale, R.; Ruckebusch, C.; Vandenberg, W.; Dedecker, P.
10.1101/2023.04.29.538742 — biophysics — Posted on 2023-08-08
3394 CASP15 cryoEM protein and RNA targets: refinement and analysis using experimental maps
Mulvaney, T.; Kretsch, R. C.; Elliott, L.; Beton, J. G.; Kryshtafovych, A.; Rigden, D.; Das, R.; Topf, M.
10.1101/2023.08.07.552287 — bioinformatics — Posted on 2023-08-08
3395 PhyloMatcher: a tool for resolving conflicts in taxonomic nomenclature
Rader, J. A.; Pivovarnik, M. A.; Vantilburg, M. E.; Whitehouse, L. S.
10.1101/2023.08.07.552263 — bioinformatics — Posted on 2023-08-08
3396 OPTIMAL: An OPTimsed Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration
Hunter, B.; Nicorescu, I.; Foster, E.; McDonald, D.; Hulme, G.; Fuller, A.; Thomson, A.; Goldsborough, T.; Hilkens, C.; Majo, J.; Milross, L.; Fisher, A. J.; Bankhead, P.; Wills, J. W.; Rees, P.; Filby, A.; Merces, G.
10.1101/2023.02.21.526083 — bioinformatics — Posted on 2023-08-08
3397 Rechargeable Biomineral Induced by Sulfate Reducing Bacterium Cupidesulfovibrio sp. HK-II
Arashi, Y.; Mochihara, H.; Kubota, H.; Suzuki, K.; Chiba, Y.; Kato, Y.; Kogure, T.; Moriuchi, R.; Dohra, H.; Tashiro, Y.; Futamata, H.
10.1101/2023.08.07.552368 — bioengineering — Posted on 2023-08-08
3402 Presence of Aedes aegypti in a high-altitude area in Bolivia
Rios-Escalier, C.; Rosas, N.; Delgadillo-Iglesias, M.; Solis-Soto, M. T.
10.1101/2023.08.07.552199 — evolutionary biology — Posted on 2023-08-08
3403 Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humans
Lardenois, A.; Suglia, A.; Moore, C. L.; Evrard, B.; Noel, L.; Rivaud, P.; Besson, A.; Toupin, M.; Leonard, S.; Lesne, L.; Coiffec, I.; Nef, s.; Lavoue, V.; Collin, O.; Chedotal, A.; Mazaud-Guittot, S.; Chalmel, F.; Rolland, A. D.
10.1101/2023.08.07.552336 — developmental biology — Posted on 2023-08-08
3404 Single-molecule analysis of transcription activation: Dynamics of SAGA co-activator recruitment
Jeon, J.; Friedman, L. J.; Seo, H. D.; Adeleke, A.; Graham, B.; Patteson, E.; Gelles, J.; Buratowski, S.
10.1101/2023.08.07.552353 — molecular biology — Posted on 2023-08-08
3405 A New World begomovirus infecting Cotton in Argentina
Delfosse, V.; Debat, H.; Zavallo, D.; Moyano, S.; Luna, F.; Bonacic Kresic, I.; Asurmendi, S.; Gomez-Talquenca, S.; Distefano, A. J.
10.1101/2020.02.20.957548 — microbiology — Posted on 2023-08-08
3406 Infant gut bacteriophage strain persistence during the first three years of life
Lou, Y. C.; Chen, L.; Borges, A. L.; West-Roberts, J. A.; Firek, B. A.; Morowitz, M.; Banfield, J.
10.1101/2023.08.07.552389 — microbiology — Posted on 2023-08-08
3407 Single-cell somatic copy number variants in brain using different amplification methods and reference genomes
Kalef-Ezra, E.; Turan, Z. G.; Perez-Rodriguez, D.; Bomann, I.; Behera, S.; Morley, C.; Scholz, S. W.; Jaunmuktane, Z.; Demeulemeester, J.; Sedlazeck, F.; Proukakis, C.
10.1101/2023.08.07.552289 — neuroscience — Posted on 2023-08-08
3408 A collaboration between immune cells and the choroid plexus epithelium in brain inflammation
Xu, H.; Lotfy, P.; Gelb, S.; Pragana, A.; Hehnly, C.; Shipley, F. B.; Zawadzki, M. E.; Cui, J.; Deng, L.; Taylor, M.; Webb, M.; Lidov, H. G. W.; Andermann, M. L.; Chiu, I. M.; Ordovas-Montanes, J.; Lehtinen, M. K.
10.1101/2023.08.07.552298 — neuroscience — Posted on 2023-08-08
3409 osl-dynamics: A toolbox for modelling fast dynamic brain activity
Gohil, C.; Huang, R.; Roberts, E.; van Es, M. W. J.; Quinn, A. J.; Vidaurre, D.; Woolrich, M. W.
10.1101/2023.08.07.549346 — neuroscience — Posted on 2023-08-08
3412 Learning induces unique transcriptional landscapes in the auditory cortex
Graham, G.-E.; Chimenti, M. S.; Knudtson, K.; Grenard, D. N.; Co, L.; Sumner, M.; Tchou, T.; Bieszczad, K. M.
10.1101/2023.04.15.536914 — neuroscience — Posted on 2023-08-08
3413 Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine
Jain, S.; Yee, A. G.; Maas, J.; Gierok, S.; Xu, H.; Stansil, J.; Eriksen, J.; Nelson, A.; Silm, K.; Ford, C. P.; Edwards, R. H.
10.1101/2023.08.07.552338 — neuroscience — Posted on 2023-08-08
3415 Tofacitinib effects profound seizure suppression through mimicking EZH2 antagonism of a pro-inflammatory gene network in epilepsy.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-08-08
3417 The synapsin-dependent vesicle cluster is crucial for presynaptic plasticity at a glutamatergic synapse in male mice
Bruentgens, F.; Moreno-Velasquez, L.; Stumpf, A.; Parthier, D.; Breustedt, J. M.; Benfenati, F.; Milovanovic, D.; Schmitz, D.; Orlando, M.
10.1101/2023.08.08.549335 — neuroscience — Posted on 2023-08-08
3418 AI in Paleontology
Yu, C.; Qin, F.; Watanabe, A.; Yao, W.; Li, Y.; Qin, Z.; Liu, Y.; Wang, H.; Jiangzuo, Q.; Hsiang, A. Y.; Ma, C.; Rayfield, E.; Benton, M. J.; Xu, X.
10.1101/2023.08.07.552217 — paleontology — Posted on 2023-08-08
3419 Novel Biomarkers and Distinct Transcriptomic Profile of Barrett's Esophagus Epithelial Stem Cells
Alexander, K. L.; Smythies, L. E.; Kyanam-Kabir-Baig, K. R.; Poovey, E.; Crossman, D. K.; Smith, P. D.; Peter, S.
10.1101/2023.08.07.552218 — cancer biology — Posted on 2023-08-08
3422 Benchmarking combined informatics approaches for virus discovery: Caution is needed when combining in silico identification methods
Hegarty, B.; Riddell, J.; Bastien, G. E.; Langenfeld, K.; Lindback, M.; Saini, J. S.; Wing, A.; Zhang, J.; Duhaime, M.
10.1101/2023.08.07.552334 — bioinformatics — Posted on 2023-08-08
3427 The actin binding protein profilin 1 is critical for mitochondria function
Read, T.-A.; Cisterna, B. A.; Skruber, K.; Ahmadieh, S.; Lindamood, H. L.; Vitriol, J.; Shi, Y.; Lefebvre, A. E. Y. T.; Black, J. B.; Butler, M. T.; Bear, J. E.; Cherezova, A.; Ilatovskaya, D. V.; Weintraub, N. L.; Vitriol, E. A.
10.1101/2023.08.07.552354 — cell biology — Posted on 2023-08-08
3431 Development of neonatal connectome dynamics and its prediction for cognitive and language outcomes at age 2
Xu, Y.; Liao, X.; Lei, T.; Zhao, J.; Zhao, T.; Li, Q.; Jeon, T.; Ouyang, M.; Chalak, L.; Rollins, N.; Huang, H.; He, Y.
10.1101/2023.08.07.552267 — neuroscience — Posted on 2023-08-08
3433 36-year study reveals stability of a wild wheat population across microhabitats
Dahan-Meir, T.; Ellis, T. J.; Mafessoni, F.; Sela, H.; Rudich, O.; Manisterski, J.; Avivi-Ragolsky, N.; Raz, A.; Feldman, M.; Anikster, Y.; Nordborg, M.; Levy, A. A.
10.1101/2022.01.10.475641 — evolutionary biology — Posted on 2023-08-08
3435 Development of connectome dynamics at birth predicts neurocognitive outcomes at age 2
Xu, Y.; Liao, X.; Lei, T.; Zhao, J.; Zhao, T.; Li, Q.; Jeon, T.; Ouyang, M.; Chalak, L.; Rollins, N.; Huang, H.; He, Y.
10.1101/2023.08.07.552267 — neuroscience — Posted on 2023-08-07
3437 The scale-invariant covariance spectrum of brain-wide activity
Wang, Z.; Mai, W.; Chai, Y.; Qi, K.; Ren, H.; Shen, C.; Zhang, S.; Tan, G.; Hu, Y.; Wen, Q.
10.1101/2023.02.23.529673 — neuroscience — Posted on 2023-08-08
3439 Many morphs: parsing gesture signals from the noise
Mielke, A.; Badihi, G.; Graham, K. E.; Grund, C.; Hashimoto, C.; Piel, A. K.; Safryghin, A.; Slocombe, K. E.; Stewart, F.; Wilke, C.; Zuberbühler, K.; Hobaiter, C.
10.1101/2023.08.07.551967 — animal behavior and cognition — Posted on 2023-08-07
3440 Multi-organ single-cell RNA-sequencing reveals early hyperglycaemia responses that converge on fibroblast dysregulation
Braithwaite, A. T.; Akbar, N.; Pezzolla, D.; Paget, D.; Krausgruber, T.; Bock, C.; Carnicer, R.; Choudhury, R. P.
10.1101/2023.08.07.552307 — cell biology — Posted on 2023-08-07
3441 The actin binding protein profilin 1 is critical for mitochondria function
Read, T.-A.; Cisterna, B. A.; Skruber, K.; Ahmadieh, S.; Lindamood, H. L.; Vitriol, J.; Shi, Y.; Lefebvre, A. E. Y. T.; Black, J. B.; Butler, M. T.; Bear, J. E.; Cherezova, A.; Ilatovskaya, D. V.; Weintraub, N. L.; Vitriol, E. A.
10.1101/2023.08.07.552354 — cell biology — Posted on 2023-08-07
3442 Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network
Polley, S.; Raisch, T.; Koerner, M.; Terbeck, M.; Graeter, F.; Raunser, S.; Aponte-Santamaria, C.; Vetter, I. R.; Musacchio, A.
10.1101/2023.08.07.552315 — molecular biology — Posted on 2023-08-07
3446 Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
Li, W.; Sparks, R. P.; Sun, C.; Yang, Y.; Pantano, L.; Kirchner, R.; Chen, J. Y.; Moran, S. P.; Barrera, V.; Wrobel, D.; Sui, S. J. H.; Aspnes, G.; Schuler, M.; Smith, J.; Medoff, B. D.; Boustany-Kari, C. M.; Rippmann, J. F.; Santos, D. M.; Doerner, J. F.; Mullen, A. C.
10.1101/2023.08.07.551744 — cell biology — Posted on 2023-08-07
3447 Recombinant SARS-CoV-2 lacking initiating and internal methionine codons within ORF10 is attenuated in vivo
Gu, S.; Bentley, E. G.; Milligan, R. I.; Almuqrin, A. M.; Sharma, P.; Kirby, A.; Mega, D. F.; Kipar, A.; Erdmann, M.; Bazire, J.; Heesom, K. J.; Lewis, P. A.; Donovan-Banfield, I.; Reston, C.; Webb, I.; de Neck, S.; Dong, X.; Hiscox, J. A.; Davidson, A. D.; Stewart, J. P.; Matthews, D. A.
10.1101/2023.08.04.551973 — microbiology — Posted on 2023-08-07
3450 Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors
Xiao, Z.; Tood, L.; Huang, L.; Noguera-Ortega, E.; Lu, Z.; Huang, L.; Kopp, M.; Li, Y.; Pattada, N. B.; Zhong, W.; Guo, W.; Schollor, J.; Liousia, M.; Assenmacher, C.-A.; June, C. H.; Albelda, S. M.; Pure, E.
10.1101/2023.04.13.536777 — immunology — Posted on 2023-08-07
3451 AAV-HBV mouse model replicates immune exhaustion patterns of chronic HBV patients at single-cell level
Conceicao-Neto, N.; Han, Q.; Yao, Z.; Pierson, W.; Wu, Q.; Dockx, K.; Aerts, L.; De Maeyer, D.; Van den Berge, K.; Li, C.; Kukolj, G.; Zhu, R.; Podlaha, O.; Najera, I.; Van Gulck, E.
10.1101/2023.08.07.552328 — immunology — Posted on 2023-08-07
3452 Mucosal and systemic immune dynamics associated with COVID-19 outcomes: a longitudinal prospective clinical study
Agrawal, M.; Flores-Torres, A. S.; Franks, J. S.; Lang, S. Y.; Fabrizio, T. P.; McNair, K. E.; Boywid, L. V.; Blair, A. J.; Hundman, C. N.; Hysmith, N. D.; Whitt, M. A.; Keating, R.; Thomas, P. G.; Webby, R. J.; Green, A. M.; Smallwood, H. S.
10.1101/2023.08.04.551867 — immunology — Posted on 2023-08-07
3454 Characterization of m6A modifiers and RNA modifications in uterine fibroids
George, J. W.; Cancino, R.; Miller, J. L. G.; Qiu, F.; Lin, Q.; Rowley, J.; Chennathukuzhi, V.; Davis, J. S.
10.1101/2023.08.07.552278 — cancer biology — Posted on 2023-08-07
3455 FRET-guided modeling of nucleic acids
Steffen, F. D.; Cunha, R. A.; Sigel, R. K. O.; Borner, R.
10.1101/2023.08.07.552238 — biophysics — Posted on 2023-08-07
3457 DNA Nanostructure-Guided Assembly of Proteins into Programmable Shapes
Lu, Q.; Xu, Y.; Poppleton, E.; Zhou, K.; Sulc, P.; Stephanopoulos, N.; Ke, Y.
10.1101/2023.08.07.552347 — bioengineering — Posted on 2023-08-07
3458 Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase
Jahn, H.; Bartos, L.; Dearden, G. I.; Dittman, J. S.; Holthuis, J. C. M.; Vacha, R.; Menon, A. K.
10.1101/2022.10.17.512472 — biochemistry — Posted on 2023-08-07
3459 Heme exporter FLVCR regulates mitochondrial biogenesis and redox balance in the hematophagous insect Rhodnius prolixus
Walter-Nuno, A. B.; Taracena-Agarwal, M.; Oliveira, M. P.; Oliveira, M.; Oliveira, P. L.; Paiva-SIlva, G. O.
10.1101/2023.08.07.552335 — biochemistry — Posted on 2023-08-07
3460 Purifying selection and adaptive evolution proximate to the zoonosis of SARS-CoV-1 and SARS-CoV-2
Townsend, J. P.; Gaughran, S.; Hassler, H. B.; Fisk, J. N.; Nagib, M.; Wu, Y.; Wang, Y.; Wang, Z.; Galvani, A. P.; Dornburg, A.
10.1101/2023.08.07.552269 — evolutionary biology — Posted on 2023-08-07
3462 c-Src-dependent phosphorylation of Mfn2 regulates endoplasmic reticulum-mitochondria tethering
Zhang, P.; Ford, K.; Sung, J. H.; Suzuki, Y.; Landherr, M.; Moeller, J.; Chaput, I.; Polina, I.; Kelly, M.; Nieto, B.; Tachibana, T.; Kusakari, Y.; Cypress, M. W.; Drenkova, K.; Adaniya, S. M.; Mishra, J.; Mende, U.; Jhun, B. S.; O-Uchi, J.
10.1101/2022.02.21.481295 — cell biology — Posted on 2023-08-07
3466 CD4+ T cell senescence is associated with reduced reactogenicity in severe/critical COVID-19
Zhang, J.; Chang, C.; Liang, Z.; Hu, T.; Yin, Z.; Liang, Y.; Zhang, T.; Ding, Y.; Li, X.; Gai, X.; Yang, X.; Li, X.; Dong, X.; Ren, J.; Rao, Y.; Wang, J.; Yang, J.; Sun, Y.; Xue, L.
10.1101/2023.08.04.551565 — immunology — Posted on 2023-08-07
3468 A competitive disinhibitory network for robust optic flow processing in Drosophila
Erginkaya, M.; Cruz, T. L.; Brotas, M.; Steck, K.; Nern, A.; Torrao, F.; Varela, N.; Bock, D.; Reiser, M. B.; Chiappe, M. E.
10.1101/2023.08.06.552150 — neuroscience — Posted on 2023-08-07
3469 Rastermap: a discovery method for neural population recordings
Stringer, C.; Zhong, L.; Syeda, A.; Du, F.; Kesa, M.; Pachitariu, M.
10.1101/2023.07.25.550571 — neuroscience — Posted on 2023-08-07
3472 Analytical code sharing practices in biomedical research
Sharma, N. K.; Ayyala, R.; Deshpande, D.; Patel, Y. M.; Munteanu, V.; Ciorba, D.; Fiscutean, A.; Vahed, M.; Sarkar, A.; Guo, R.; Moore, A.; Darci-Maher, N.; Nogoy, N. A.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2023.07.31.551384 — scientific communication and education — Posted on 2023-08-07
3473 Spatial Co-transcriptomics Reveals Discrete Stages of the Arbuscular Mycorrhizal Symbiosis
Serrano, K.; Bezrutczyk, M.; Goudeau, D.; Dao, T.; O'Malley, R. C.; Malmstrom, R. R.; Visel, A.; Scheller, H. V.; Cole, B.
10.1101/2023.08.02.551648 — plant biology — Posted on 2023-08-07
3475 Pathogenic entero- and salivatypes harbour changes in microbiome virulence and antimicrobial resistance genes with increasing chronic liver disease severity
Lee, S.; Arefaine, B.; Begum, N.; Stamouli, M.; Witherden, E.; Mohamad, M.; Harzandi, A.; Zamalloa, A.; Cai, H.; Edwards, L. A.; Williams, R.; Chokshi, S.; Mardinoglu, A.; Proctor, G.; Shawcross, D. L.; Moyes, D.; Uhlen, M.; Shoaie, S.; Patel, V. C.
10.1101/2023.08.06.552152 — physiology — Posted on 2023-08-07
3476 Carcinogen induced expansion of atypical B cells and pre-treatment tumor adjacent tertiary lymphoid structures associate with poor response to BCG in non-muscle invasive bladder cancer
Yolmo, P.; Rahimi, S.; Chenard, S.; Conseil, G.; Jenkins, D.; Emon, I.; Hamilton, J.; Xu, M.; Rangachari, M.; Michaud, E.; Mansure, J.; Berman, D. M.; Siemens, D. R.; Koti, M.
10.1101/2022.12.30.522127 — cancer biology — Posted on 2023-08-07
3478 Smoother: A Unified and Modular Framework for Incorporating Structural Dependency in Spatial Omics Data
Su, J.; Reynier, J.-B.; Fu, X.; Zhong, G.; Jiang, J.; Supo Escalante, R.; Wang, Y.; Aparicio, L.; Izar, B.; Knowles, D. A.; Rabadan, R.
10.1101/2022.10.25.513785 — bioinformatics — Posted on 2023-08-07
3480 Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition
Heil, L. R.; Damoc, N. E.; Arrey, T. N.; Pashkova, A.; Denisov, E.; Petzoldt, J.; Peterson, A.; Hsu, C.; Searle, B. C.; Shulman, N.; Riffle, M.; Connolly, B.; MacLean, B. X.; Remes, P. M.; Senko, M.; Stewart, H.; Hock, C.; Makarov, A.; Hermanson, D.; Zabrouskov, V.; Wu, C. C.; MacCoss, M. J.
10.1101/2023.06.03.543570 — biochemistry — Posted on 2023-08-07
3482 Gas tunnel engineering of an iron-based oxygen sensor reprograms cellular hypoxia signaling
Windsor, P.; Ouyang, H.; da Costa, J. A. G.; Damodaran, A. R.; Chen, Y.; Bhagi-Damodaran, A.
10.1101/2023.08.07.552357 — biochemistry — Posted on 2023-08-07
3485 Transposable element expression with variation in gonosome number supports a toxic Y effect on human longevity
Teoli, J.; Fablet, M.; Bardel, C.; Necsulea, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2023-08-07
3486 Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes
Yan, D.; Hu, B.; Darst, B. F.; Mukherjee, S.; Kunkle, B. W.; Deming, Y.; Dumitrescu, L.; Wang, Y.; Naj, A.; Kuzma, A.; Zhao, Y.; Kang, H.; Johnson, S. C.; Cruchaga, C.; Hohman, T. J.; Crane, P.; Engelman, C. D.; Alzheimer's Disease Genetics Consortium, ; Lu, Q.
10.1101/468306 — genetics — Posted on 2023-08-07
3490 Bloodmeal metabarcoding of the argasid tick (Ornithodoros turicata Duges) reveals extensive vector-host associations
Balasubramanian, S.; Busselman, R. E.; Santos, N. F.; Grunwald, A.; Wolff, N.; Hathaway, N.; Hillhouse, A.; Bailey, J. A.; Teel, P. D.; Ferreira, F. C.; Hamer, S. A.; Hamer, G. L.
10.1101/2023.08.07.552345 — ecology — Posted on 2023-08-07
3491 The mitophagy receptor Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Field, J. T.; Chapman, D.; Ghavami, S.; West, A. R.; Saleem, A.; Kindrachuk, J.; Triggs-Raine, B.; Gordon, J. W.
10.1101/2023.03.18.532760 — cell biology — Posted on 2023-08-07
3492 Reducing brain kynurenic acid synthesis precludes kynurenine-induced sleep disturbances
Rentschler, K. M.; Milosavljevic, S.; Baratta, A. M.; Wright, C. J.; Piroli, M. V.; Tentor, Z.; Valafar, H.; O'Reilly, C.; Pocivavsek, A.
10.1101/2022.11.21.517377 — neuroscience — Posted on 2023-08-07
3493 Directional uncertainty in chase and escape dynamics
Trevino, M.; Medina-Coss y Leon, R.; Tamez, S.; Beltran-Navarro, B.; Verdugo Molina, J.
10.1101/2023.08.06.552194 — neuroscience — Posted on 2023-08-07
3495 Habitat use of loggerhead (Caretta caretta) and green (Chelonia mydas) turtles in the Northwest Pacific Ocean, the northern limit of their distribution range
Kim, I.-H.; Park, I.-K.; Park, D.; Kim, M.-S.; Cho, I.-Y.; Yang, D.; Han, D.-J.; Cho, E.; Shim, W. J.; Hong, S. H.; An, Y.-R.
10.1101/2023.08.06.552178 — zoology — Posted on 2023-08-07
3496 Molecular pharmacology of selective NaV1.6 and dual NaV1.6 and NaV1.2 channel inhibitors that suppress excitatory neuronal activity ex vivo
Goodchild, S. J.; Shuart, N. G.; Williams, A. D.; Ye, W.; Parrish, R. R.; Soriano, M.; Thouta, S.; Mezeyova, J.; Waldbrook, M.; Dean, R. A.; Focken, T.; Ghovanloo, M.-R.; Ruben, P. C.; Scott, F.; Cohen, C. J.; Empfield, J. R.; Johnson, J.
10.1101/2023.08.03.551643 — pharmacology and toxicology — Posted on 2023-08-07
3497 NaV1.6 inhibition drives the efficacy of voltage-gated sodium channel inhibitors to prevent electrically induced seizures in both wild type and Scn8aN1768D/+ gain-of-function mice
Johnson, J.; Focken, T.; Tari, P. K.; Dube, C.; Goodchild, S. J.; Andrez, J.-C.; Bankar, G.; Burford, K.; Chang, E.; Chowdhury, S.; Christabel, J.; Dean, R. A.; de Boer, G.; Dehnhardt, C.; Gong, W.; Grimwood, M.; Hussainkhel, A.; Jia, Q.; Khakh, K.; Lee, S.; Li, J.; Lin, S.; Lindgren, A.; Lofstrand, V.; Mezeyova, J.; Nelkenbrecher, K.; Shuart, N. G.; Sojo, L.; Sun, S.; Waldbrook, M.; Wesolowski, S.; Wilson, M.; Xie, Z.; Zenova, A.; Zhang, W.; Scott, F.; Cutts, A. J.; Sherrington, R. P.; Winquist, R.; Cohen, C. J.; Empfield, J. R.
10.1101/2023.08.03.551823 — pharmacology and toxicology — Posted on 2023-08-07
3498 Long-term selection on mitocoding genes buried in mammalian and avian nuclear genomes
Chen, Y.-C.; Vendrami, D. L.; Huber, M. L.; Handel, L. E.; Cooney, C. R.; Hoffman, J.; Gossmann, T.
10.1101/2023.08.07.552327 — evolutionary biology — Posted on 2023-08-07
3499 The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling
Pelz, L.; Dossou, L.; Kompier, N.; Juttner, R.; Siemonsmeier, G.; Meyer, N.; Lowenstein, E. D.; Lahmann, I.; Kettenmann, H.; Birchmeier, C.; Rathjen, F. G.
10.1101/2022.06.17.496568 — cell biology — Posted on 2023-08-07
3500 A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling
Raynaud, P.; Jugnarain, V.; Vaugrente, O.; Vallet, A.; Boulo, T.; Gauthier, C.; Gauthier, C.; Jean-Alphonse, F.; Reiter, E.; Crepieux, P.; Bruneau, G.
10.1101/2023.08.07.552286 — pharmacology and toxicology — Posted on 2023-08-07
3503 Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids
Haloi, N.; Huang, S.; Nichols, A. L.; Fine, E. J.; Friesenhahn, N. J.; Marotta, C. B.; Dougherty, D. A.; Lindahl, E.; Howard, R. J.; Mayo, S. L.; Lester, H. A.
10.1101/2023.01.16.524298 — bioengineering — Posted on 2023-08-07
3505 Two dramatically distinct archaeal type IV pili structures formed by the same pilin
Liu, J.; Eastep, G. N.; Cvirkaite-Krupovic, V.; Rich-New, S. T.; Kreutzberger, M. A. B.; Egelman, E. H.; Krupovic, M.; Wang, F.
10.1101/2023.08.07.552285 — microbiology — Posted on 2023-08-07
3508 A pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin 1 axis
Li, R.; Colombo, M.; Wang, G.; Rodriguez-Romera, A.; O'Sullivan, J.; Clark, S.-A.; Perez Saez, J.; Meng, Y.; Khan, A.; Wen, S.; Dong, P.; Zhou, W.; Sousos, N.; Murphy, L.; Clarke, M.; Jooss, N.; Olijnik, A.-A.; Wong, Z.; Sirinukunwattana, K.; Ryou, H.; Norfo, R.; Cheng, Q.; Brierley, C.; Carrelha, J.; Ren, Z.; Thongjuea, S.; Rathinam, V.; Krishnan, A. K.; Royston, D.; Rabinovich, G.; Mead, A.; Psaila, B.
10.1101/2023.08.05.550630 — cancer biology — Posted on 2023-08-07
3509 Stress response of fire salamander larvae differs between habitat types
Schulte, L.; Oswald, P.; Muehlenhaupt, M.; Ossendorf, E.; Kruse, S.; Kaiser, S.; Caspers, B. A.
10.1101/2023.08.07.552279 — ecology — Posted on 2023-08-07
3511 CryoEM reveals the structure of an archaeal pilus involved in twitching motility
Gaines, M. C.; Sivabalasarma, S.; Isupov, M. N.; Haque, R. U.; McLaren, M.; Hanus, C.; Gold, V. A. M.; Albers, S.-V.; Daum, B.
10.1101/2023.08.07.552258 — microbiology — Posted on 2023-08-07
3512 Low prevalence of HLA-G antibodies in lung transplant patients detected by MAIPA adapted protocol
PEDINI, P.; HUBERT, L.; Carlini, F.; Baudey, J. B.; TOUS, A.; Jordier, F.; Basire, A.; Bagnis, C.; Reynaud-Gaubert, M.; Coiffard, B.; Chiaroni, J.; Silvy, M.; Picard, C.
10.1101/2023.08.04.551968 — immunology — Posted on 2023-08-07
3513 VmPFC supports persistence during goal pursuit through selective attention
Holton, E. R.; Grohn, J. R.; Ward, H.; Manohar, S. G.; O'Reilly, J. X.; Kolling, N.
10.1101/2023.08.07.552276 — neuroscience — Posted on 2023-08-07
3514 Decoding auditory working memory content from intracranial high frequency activity in humans
Uluc, I.; Peled, N.; Paulk, A. C.; Bush, A.; Gumenyuk, V.; Kotlarz, P. L.; Lankinen, K.; Mamashli, F.; Matsuda, N.; Richardson, M.; Stufflebeam, S. M.; Cash, S. S.; Ahveninen, J.
10.1101/2023.08.04.552073 — neuroscience — Posted on 2023-08-07
3515 Nutrient levels control root growth responses to high ambient temperature in plants
Lee, S.; Showalter, J.; Zhang, L.; Cassin-Ross, G.; Rouached, H.; Busch, W.
10.1101/2023.08.04.552051 — plant biology — Posted on 2023-08-07
3517 An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants
Nmezi, B.; Bey, G. R.; Oranburg, T. D.; Dudnyk, K.; Morgan, S.; Herdman, N.; Jacko, A.; Rubio, S.; Alcocer, E. L.; Kofler, J.; Kim, D.; Rankin, J.; Kivuva, E.; Gutowski, N.; Schon, K.; van den Ameele, J.; Chinnery, P. F.; Sousa, S. B.; Palavra, F.; Toro, C.; Pinto e Vairo, F.; Saute, J.; Pan, L.; Alturkustani, M.; Hammond, R.; Gros-Louis, F.; Gold, M.; Park, Y.; Bernard, G.; Raininko, R.; Zhou, J.; Hainer, S.; Padiath, Q.
10.1101/2023.08.03.551473 — genetics — Posted on 2023-08-07
3518 Shared and distinct molecular effects of regulatory genomic variants provide insight into mechanisms of distal enhancer-promoter communication
Ray-Jones, H.; Song, Z.; Haglund, A.; Artemov, P.; Della Rosa, M.; Burden, F.; Kreuzhuber, R.; Litovskikh, A.; Tan, V. X. H.; Chan, L. T.; Frontini, M.; Wallace, C.; Malysheva, V.; Bottolo, L.; Vigorito, E.; Spivakov, M.
10.1101/2023.08.04.551251 — genetics — Posted on 2023-08-07
3519 RNA-mediated ribonucleoprotein assembly controls TDP-43 nuclear retention
dos Passos, P. M.; Hemamali, E. H.; Mamede, L. D.; Hayes, L. R.; Ayala, Y. M.
10.1101/2023.08.06.552215 — cell biology — Posted on 2023-08-07
3520 Gene-to-Gene Coordinated Regulation of Transcription and Alternative splicing by 3D Chromatin Remodeling upon NF-κB activation
Marie, P.; Ladet, J.; Bazire, M.; Ameur, L. B.; Chahar, S.; Fontrodona, N.; Sexton, T.; Auboeuf, D.; Bourgeois, C.; Mortreux, F.
10.1101/2023.08.07.552259 — molecular biology — Posted on 2023-08-07
3521 The Shape of Cannabis sativa L. Seeds for the Differentiation of Commercial Medicinal Cultivars from Argentina.
Fernandez Torne, F.; Bosco, T.; Idaszkin, Y. L.; Garces, N.; Lozada, M.; Gonzalez, J. R.; Marquez, F.
10.1101/2023.08.07.552192 — plant biology — Posted on 2023-08-07
3522 Enhancement of High-Density Lipoprotein-Associated Protease Inhibitor Activity Prevents Atherosclerosis Progression
Mobilia, M.; Karakashian, A.; Whitus, C.; Neupane, K. R.; Johnson, L. A.; Graf, G. A.; Gordon, S. M.
10.1101/2023.08.07.551670 — physiology — Posted on 2023-08-07
3525 Large-scale lensless microscopy with fast acquisition and region-wise focusing
Zhou, Y.; Song, W.; Wu, L.; Fan, L.; Wang, J.; Jiang, S.; Ma, Z.; Xiong, B.; Cao, X.
10.1101/2023.08.05.551428 — bioengineering — Posted on 2023-08-07
3526 Large-scale population genomics of Malayan pangolins reveals deep diversification and a new species
Li, B.; Lan, T.; Wang, Q.; Shi, M.; Guo, C.; Li, H.; Liu, B.; Liu, S.; Finch, K.; Wang, S.; Yang, S.; Cui, L.; Li, J.; Zhao, X.; Wang, J.; Deng, Z.; Wang, X.; Ma, Y.; Kim, H. J.; Wasser, S. K.; Wang, K.; Lu, H.; Yang, D.; Chen, J.; Guo, H.; Yao, Y.; Xie, H.; Wang, Y.; Fan, J.; Li, W.; Niu, X.; Hou, Y.; Yu, J.; Lu, J.; Li, S.; Qiu, Z.; Zhang, W.; Bai, S.; Han, L.; Wu, Y.; Cai, X.; Huang, Y.; Wang, Z.; Wang, C.; Li, J.; Jiang, Y.; Liu, S.; Wang, J.; Li, L.; Hua, Y.; Liu, H.; Xu, Y.
10.1101/2023.08.07.548787 — genomics — Posted on 2023-08-07
3528 Mitochondrial DNA released by senescent cells triggers immunosuppression in cancer
Lai, P.; Liu, L.; Bancaro, N.; Troiani, M.; Cali, B.; Chen, J.; Singh, P. K.; Arzola, R. A.; Attanasio, G.; Pernigoni, N.; Pasquini, E.; Mosole, S.; Rinaldi, A.; Sgrignani, J.; Li, Y.; Qiu, S.; Song, P.; Li, Y.; Desbats, M. A.; Angel, A. R.; Mestre, R. P.; Barile, L.; Cavalli, A.; Bono, J. d.; Alimonti, A.
10.1101/2023.08.06.551763 — cell biology — Posted on 2023-08-07
3529 Loss of HSC stemness identity is associated with exhaustion and hyporesponsiveness in GATA2 deficiency syndrome
Largeaud, L.; Fregona, V.; Jamrog, L.; Hamelle, C.; Dufrechou, S.; Prade, N.; Sellam, E.; Enfedaque, P.; Bayet, M.; Hebrard, S.; Bouttier, M.; Didier, C.; Delabesse, E.; Gerby, B.; Pasquet, M.; Broccardo, C.
10.1101/2023.08.07.551811 — cell biology — Posted on 2023-08-07
3530 Structure of the human outer kinetochore KMN network complex
Yatskevich, S.; Yang, J.; Bellini, D.; Zhang, Z.; Barford, D.
10.1101/2023.08.07.552234 — cell biology — Posted on 2023-08-07
3534 Machine learning models for prediction of xenobiotic chemicals with high propensity to transfer into human milk
Vijayaraghavan, S.; Lakshminarayanan, A.; Bhargava, N.; Ravichandran, J.; Vivek-Ananth, R. P.; Samal, A.
10.1101/2023.08.06.552173 — pharmacology and toxicology — Posted on 2023-08-07
3539 The impact of ZIKV infection on gene expression in neural cells over time
Rodrigues, M. d. S.; Junior, A. M. P.; Fukutani, E. R.; Pereira, M. A.; Salgado, V. R.; Queiroz, A. T. L.
10.1101/2023.08.06.552183 — bioinformatics — Posted on 2023-08-07
3542 Variant annotation across homologous proteins (Paralogue Annotation) identifies disease-causing missense variants with high precision, and is widely applicable across protein families
Li, N.; Mazaika, E.; Theotokis, P.; Zhang, X.; Jang, M.; Ahmad, M.; Powell, G.; Heyne, H. O.; Lal, D.; Barton, P. J.; Walsh, R.; Whiffin, N.; Ware, J. S.
10.1101/2023.08.07.552236 — bioinformatics — Posted on 2023-08-07
3550 Using deep long-read RNAseq in Alzheimer's disease brain to assess clinical relevance of RNA isoform diversity
Aguzzoli Heberle, B.; Brandon, J. A.; Page, M. L.; Nations, K. A.; Dikobe, K. I.; White, B. J.; Gordon, L. A.; Fox, G. A.; Wadsworth, M. E.; Doyle, P. H.; Fox, E. J.; Shantaraman, A.; Ryten, M.; Goodwin, S.; Ghiban, E.; Wappel, R.; Mavruk-Eskpelivan, S.; Miller, J. B.; Seyfried, N.; Nelson, P. T.; Fryer, J. D.; Ebbert, M. T. W.
10.1101/2023.08.06.552162 — genomics — Posted on 2023-08-07
3551 Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation
Cheng, K. C. L.; Frost, J. M.; Sanchez-Luque, F. J.; Garcia-Canadas, M.; Taylor, D.; Yang, W. R.; Irayanar, B.; Sampath, S.; Patani, H.; Agger, K.; Helin, K.; Ficz, G.; Burns, K. H.; Ewing, A. D.; Garcia-Perez, J. L.; Branco, M. R.
10.1101/2023.08.07.552254 — genetics — Posted on 2023-08-07
3554 Environmental effects on reproductive performance in preindustrial women
Colejo Duran, L.; Pelletier, F.; Dillon, L.; Gagnon, A.; Bergeron, P.
10.1101/2023.08.06.552185 — ecology — Posted on 2023-08-07
3558 The two plant-specific DREAM components FLIC and FLAC repress floral transition in Arabidopsis
Lang, L.; Boewer, F.; Tuncay-Elbasi, H.; Eeckhout, D.; Marschlich, N.; de Jaeger, G.; Heese, M.; Schnittger, A.
10.1101/2023.08.07.552284 — developmental biology — Posted on 2023-08-07
3559 SIN-3 transcriptional coregulator maintains mitochondrial hormesis and polyamine flux
Palladino, F.; Giovannetti, M.; Fabrizio, P.; Nicolle, O.; Bedet, C.; Rodriguez-Palero, M.; Michaux, G.; Artal-Sanz, M.; Witting, M.
10.1101/2023.08.07.552272 — developmental biology — Posted on 2023-08-07
3562 Single Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells
Surve, M. V.; Lin, B.; Reedy, J. L.; Crossen, A. J.; Xu, A.; Klein, B. S.; Vyas, J. M.; Rajagopal, J.
10.1101/2023.08.06.552176 — cell biology — Posted on 2023-08-07
3569 Cell-free chromatin from dying cells trigger an immune response via the cGAS-STING pathway
Shabrish, S.; Raphel, N.; Narayanan, R.; Lopes, R.; Kondhalkar, D.; Khare, N. K.; Raghuram, G. V.; Mittra, I.
10.1101/2023.08.07.551233 — immunology — Posted on 2023-08-07
3570 The circadian clock is a pacemaker of the axonal regenerative ability
De Virgiliis, F.; Mueller, F.; Palmisano, I.; Chadwick, J. S.; Luengo Gutierrez, L.; Giarrizzo, A.; Yan, Y.; Danzi, M. C.; Picon Munoz, C.; Zhou, L.; Kong, G.; Serger, E.; Hutson, T. H.; Scheiermann, C.; Brancaccio, M.; Di Giovanni, S.
10.1101/2023.08.07.552230 — neuroscience — Posted on 2023-08-07
3571 A competitive disinhibitory network for robust optic flow processing in Drosophila
Erginkaya, M.; Cruz, T. L.; Brotas, M.; Steck, K.; Nern, A.; Torrao, F.; Varela, N.; Bock, D.; Reiser, M. B.; Chiappe, M. E.
10.1101/2023.08.06.552150 — neuroscience — Posted on 2023-08-07
3573 Directional uncertainty in chase and escape dynamics
Trevino, M.; Medina-Coss y Leon, R.; Beltran-Navarro, B.; Tamez, S.
10.1101/2023.08.06.552194 — neuroscience — Posted on 2023-08-07
3574 Bayesian modeling disentangles language versus executive control disruption in stroke
Hartwigsen, G.; Lim, J.-S.; Bae, H.-J.; Yu, K.-H.; Kuijf, H. J.; Weaver, N. A.; Biesbroek, J. M.; Kopal, J.; Bzdok, D.
10.1101/2023.08.06.552147 — neuroscience — Posted on 2023-08-07
3575 Insights into stereoselective ring formation in canonical strigolactone: Discovery of a dirigent domain-containing enzyme catalyzing orobanchol synthesis
Homma, M.; Wakabayashi, T.; Moriwaki, Y.; Shiotani, N.; Shigeta, T.; Isobe, K.; Okazawa, A.; Ohta, D.; Terada, T.; Shimizu, K.; Mizutani, M.; Takikawa, H.; Sugimoto, Y.
10.1101/2023.08.07.552212 — plant biology — Posted on 2023-08-07
3578 Conditional deletion of Ccl2 in smooth muscle cells does not reduce early atherosclerosis in mice
Gunnersen, S.; Shim, J. T.; Liu, F.; Tietge, U. J. F.; Sorensen, C. B.; Bentzon, J. F.
10.1101/2023.08.06.552177 — pathology — Posted on 2023-08-07
3579 A kinome-wide synthetic lethal CRISPR/Cas9 screen reveals that mTOR inhibition prevents adaptive resistance to CDK4/CDK6 blockade in HNSCC
Goto, Y.; Koshizuka, K.; Ando, T.; Izumi, H.; Wu, X.; Ford, K.; Feng, X.; Wang, Z.; Arang, N.; Allevato, M. M.; Kishore, A.; Mali, P.; Gutkind, J. S.
10.1101/2023.08.07.552216 — cancer biology — Posted on 2023-08-07
3580 RACER-m Leverages Structural Features for Sparse T Cell Specificity Prediction
Wang, A. T.; Lin, X.; Chau, K. N.; Onuchic, J. N.; Levine, H.; George, J. T.
10.1101/2023.08.06.552190 — biophysics — Posted on 2023-08-07
3584 TOM20 Gates PINK1 Activity And Mediates Its Tethering Of The TOM And TIM23 Translocases Upon Mitochondrial Stress
Eldeeb, M.; Bayne, A.; Fallahi, A.; Goiran, T.; McDougall, E.; Soumbasis, A.; Zorca, C.; Tabah, J.-J.; Thomas, R.; Karpilovsky, N.; Mathur, M.; Durcan, T.; Trempe, J.-F.; Fon, E.
10.1101/2023.08.07.552252 — biochemistry — Posted on 2023-08-07
3586 Microplastics reach the brain and interfere with honey bee cognition
Pasquini, E.; Ferrante, F.; Passaponti, L.; Pavone, F. S.; Costantini, I.; Baracchi, D.
10.1101/2023.08.05.552092 — animal behavior and cognition — Posted on 2023-08-07
3587 Do Goats Recognise Humans Cross-Modally?
Mason, M. A.; Semple, S.; Marshall, H. H.; McElligott, A. G.
10.1101/2023.08.04.551944 — animal behavior and cognition — Posted on 2023-08-07
3589 Epiboly in zebrafish requires the coordinated activity of NADPH oxidases and dynamin.
Mendez-Cruz, F. J.; Ramirez-Corona, A.; Reza-Medina, B.; Mendieta-Serrano, M. A.; Schnabel, D.; Lomeli, H.; Salas-Vidal, E.
10.1101/2023.06.30.547135 — developmental biology — Posted on 2023-08-07
3590 Reversal of Biological Age in Multiple Rat Organs by Young Porcine Plasma Fraction
Horvath, S.; Singh, K.; Raj, K.; Khairnar, S.; Sanghavi, A.; Shrivastava, A.; Zoller, J. A.; Li, C. Z.; Herenu, C. B.; Canatelli-Mallat, M.; Lehmann, M.; Habazin, S.; Vuckovic, F.; Solberg-Woods, L.; Garcia Martinez, A.; Wang, T.; Chiavellini, P.; Levine, A. J.; Chen, H.; Brooke, R. T.; Gordevicius, J.; Lauc, G.; Goya, R. G.; Katcher, H. L.
10.1101/2023.08.06.552148 — developmental biology — Posted on 2023-08-07
3592 Effects of ageing and frailty on circulating monocyte and dendritic cell subsets
Reitsema, R. D.; Kumawat, A. K.; Hesselink, B.-C.; van Baarle, D.; van Sleen, Y.
10.1101/2023.08.07.552240 — immunology — Posted on 2023-08-07
3594 Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability
Drexler, R.; Khatri, R.; Sauvigny, T.; Mohme, M.; Maire, C.; Ryba, A.; Zghaibeh, Y.; Duhrsen, L.; Salviano-Silva, A.; Lamszus, K.; Westphal, M.; Gempt, J.; Wefers, A. K.; Neumann, J.; Bode, H.; Hausmann, F.; Huber, T. B.; Bonn, S.; Jutten, K.; Delev, D.; Weber, K. J.; Harter, P. N.; Onken, J.; Vajkoczy, P.; Capper, D.; Wiestler, B.; Weller, M.; Snijder, B.; Buck, A.; Weiss, T.; Keough, M. B.; Ni, L.; Monje, M.; Silverbush, D.; Hovestadt, V.; Suva, M. L.; Krishna, S.; Hervey-Jumper, S.; Schueller, U.; Heiland, H. D.; Haenzelmann, S.; Ricklefs, F. L.
10.1101/2023.08.04.552017 — neuroscience — Posted on 2023-08-07
3597 Sparse and specific long-term plasticity emerge without homeostasis in a biophysically detailed cortical model
Ecker, A.; Egas Santander, D.; Abdellah, M.; Blanco Alonso, J.; Bolanos-Puchet, S.; Chindemi, G.; Isbister, J. B.; King, J. G.; Kumbhar, P.; Magkanaris, I.; Muller, E. B.; Reimann, M. W.
10.1101/2023.08.07.552264 — neuroscience — Posted on 2023-08-07
3598 The Therapeutic Effects of Long-term Photobiomodulation on Aging in Mice
Ahmet, I.; Syed, S. B.; Chakir, K.; Morrell, C.; Arany, P.; Lakatta, E. G.
10.1101/2023.08.05.552116 — physiology — Posted on 2023-08-07
3599 Antigen Geometry Tunes Mast Cell Signaling Through Distinct FcϵRI Aggregation andStructural Changes
Rinaldi, D. A.; Kanagy, W. K.; Kaye, H. C.; Grattan, R. M.; Lucero, S. R.; Perez, M. P.; Wester, M. J.; Lidke, K. A.; Wilson, B. S.; Lidke, D. S.
10.1101/2023.08.04.552060 — biophysics — Posted on 2023-08-07
3606 An engineered culture vessel and flow system to improve the in vitro analysis of volatile organic compounds
Eshima, J.; Pennington, T. R.; Abdellatif, Y.; Ponce Olea, A.; Lusk, J. F.; Ambrose, B. D.; Marschall, E.; Miranda, C.; Phan, P.; Aridi, C.; Smith, B. S.
10.1101/2023.08.05.552027 — bioengineering — Posted on 2023-08-07
3607 Extensive long-range polycomb interactions and weak compartmentalization are hallmarks of human neuronal 3D genome
Pletenev, I. A.; Bazarevich, M.; Zagirova, D. R.; Kononkova, A. D.; Cherkasov, A. V.; Efimova, O. I.; Tiukacheva, E. A.; Morozov, K. V.; Ulianov, K. A.; Komkov, D.; Tvorogova, A. V.; Golimbet, V. E.; Kondratyev, N. V.; Razin, S. V.; Khaitovich, P.; Ulianov, S. V.; Khrameeva, E. A.
10.1101/2023.08.04.551939 — genomics — Posted on 2023-08-07
3608 Costs of being a diet generalist in the super-generalist protist predator Dictyostelium discoideum
Shreenidhi, P. M.; Brock, D. A.; McCabe, R. I.; Strassmann, J. E.; Queller, D. C.
10.1101/2023.08.05.552129 — ecology — Posted on 2023-08-07
3610 Ontogeny of the organized nasopharynx-associated lymphoid tissue in rainbow trout
Garcia, B. J.; Reyes, A.; Martinez, C.; Serra dos Santos, Y.; Salinas, I.
10.1101/2023.08.04.552019 — immunology — Posted on 2023-08-07
3611 Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice
Borrelli, K. N.; Wingfield, K. K.; Yao, E. J.; Zamorano, C. A.; Sena, K. D.; Beierle, J. A.; Roos, M. A.; Zhang, H.; Wachman, E. M.; Bryant, C. D.
10.1101/2023.08.04.552033 — neuroscience — Posted on 2023-08-07
3615 MRIO: The Magnetic Resonance Imaging Acquisition and Analysis Ontology
Bartnik, A.; Serra, L. M.; Smith, M.; Duncan, W. D.; Wishnie, L.; Ruttenbern, A.; Dwyer, M. G.; Diehl, A. D.
10.1101/2023.08.04.552020 — bioinformatics — Posted on 2023-08-07
3618 Dynamic clustering of genomics cohorts beyond race, ethnicity--and ancestry
Mohsen, H.; Blenman, K.; Emani, P. S.; Morris, Q.; Carrot-Zhang, J.; Pusztai, L.
10.1101/2023.08.04.552035 — genomics — Posted on 2023-08-07
3621 Induction of antiviral Interferon-Stimulated Genes (ISGs) by neuronal STING promotes the resolution of pain
Defaye, M.; Bradaia, A.; Abdullah, N.; Agosti, F.; Iftinca, M.; Soubeyre, V.; Svendsen, K.; Gill, G.; Cumenal, M.; Gheziel, N.; Martin, J.; Basso, L.; Bourinet, E.; Chiu, I.; Altier, C.
10.1101/2023.08.04.551993 — neuroscience — Posted on 2023-08-07
3625 Discovery of an APP-Selective BACE1 Inhibitor for Alzheimer's Disease
Campagna, J.; Jagodzinska, B.; Wi, D.; Zhu, C.; Lee, J. T.; Cohn, W.; Jun, M.; Elias, C. J.; Descamps, O.; Zhang, Q.; Gorostiza, O.; Poksay, K.; Spilman, P.; Bredesen, D. E.; John, V.
10.1101/2023.08.04.552030 — neuroscience — Posted on 2023-08-07
3628 PDBe CCDUtils: an RDKit-based toolkit for handling and analysing small molecules in the Protein Data Bank
Kunnakkattu, I. R.; Choudhary, P.; Pravda, L.; Nadzirin, N.; Smart, O. S.; Yuan, Q.; Anyango, S.; Nair, S.; Varadi, M.; Velankar, S.
10.1101/2023.08.04.552003 — bioinformatics — Posted on 2023-08-07
3631 BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice
Lee, C. Y. D.; De La Rocha, A. J.; Inouye, K.; Langfelder, P.; Daggett, A.; Gu, X.; Jiang, L.-L.; Pamonag, Z.; Vaca, R. G.; Richman, J.; Kawaguchi, R.; Gao, F.; Xu, H.; Yang, X. W.
10.1101/2023.08.03.551881 — neuroscience — Posted on 2023-08-07
3634 Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions
Edwards, F.; Fantozzi, G.; Simon, A. Y.; Morretton, J.-P.; Herbette, A.; Tijhuis, A. E.; Wardenaar, R.; Foulane, S.; Gemble, S.; Spierings, D. C. J.; Foijer, F.; Mariani, O.; Vincent-Salomon, A.; Roman-Roman, S.; Sastre-Garau, X.; Goundiam, O.; Basto, R.
10.1101/2023.07.28.550973 — cell biology — Posted on 2023-08-07
3635 Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine
Sun, W.; Winnubst, J.; Natrajan, M.; Lai, C.; Kajikawa, K.; Michaelos, M.; Gattoni, R.; Fitzgerald, J. E.; Spruston, N.
10.1101/2023.08.03.551900 — neuroscience — Posted on 2023-08-07
3636 Sorting of secretory proteins at the trans-Golgi network by TGN46
Lujan, P.; Garcia-Cabau, C.; Wakana, Y.; Vera Lillo, J.; Rodilla-Ramirez, C.; Malhotra, V.; Salvatella, X.; Garcia-Parajo, M. F.; Campelo, F.
10.1101/2022.04.20.488883 — cell biology — Posted on 2023-08-07
3639 ECOLE: Learning to call copy number variants on whole exome sequencing data
Mandiracioglu, B.; Ozden, F.; Kaynar, G.; Yilmaz, M. A.; Alkan, C.; Cicek, A. E.
10.1101/2022.11.17.516880 — bioinformatics — Posted on 2023-08-07
3640 Terraces in Species Tree Inference from Gene Trees
Habib, M.; Roy, K.; Hasan, S.; Rahman, A. H.; Bayzid, M. S.
10.1101/2022.11.21.517454 — bioinformatics — Posted on 2023-08-07
3642 A genome-wide atlas of human cell morphology
Ramezani, M.; Bauman, J.; Singh, A.; Weisbart, E.; Yong, J.; Lozada, M. E.; Way, G. P.; Kavari, S. L.; Diaz, C.; Haghighi, M.; Perez-Schindler, J.; Batista, T. M.; Claussnitzer, M.; Singh, S.; Cimini, B. A.; Blainey, P. C.; Carpenter, A. E.; Jan, C. H.; Neal, J. T.
10.1101/2023.08.06.552164 — genomics — Posted on 2023-08-07
3648 Machine learning identification of Pseudomonas aeruginosa strains from colony image data
Rattray, J. B.; Lowhorn, R. J.; Walden, R.; Marquez Zacarias, P.; Molotkova, E.; Perron, G.; Solis-Lemus, C.; Pimentel-Alarcon, D.; Brown, S. P.
10.1101/2022.09.02.506375 — microbiology — Posted on 2023-08-07
3651 Representational similarity learning reveals a graded multi-dimensional semantic space in the human anterior temporal cortex
Cox, C. R.; Rogers, T. T.; Shimotake, A.; Kikuchi, T.; Kunieda, T.; Miyamoto, S.; Takahashi, R.; Matsumoto, R.; Ikeda, A.; Ralph, M. A. L.
10.1101/2022.10.27.514039 — neuroscience — Posted on 2023-08-07
3652 Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA
Reddy, N. A.; Zvolanek, K. M.; Moia, S.; Caballero-Gaudes, C.; Bright, M. G.
10.1101/2023.07.19.549746 — neuroscience — Posted on 2023-08-07
3653 Individual similarities and differences in eye-movement-related eardrum oscillations (EMREOs)
King, C. D.; Lovich, S. N.; Murphy, D. L. K.; Landrum, R.; Kaylie, D.; Shera, C. A.; Groh, J. M.
10.1101/2023.03.09.531896 — neuroscience — Posted on 2023-08-07
3656 Alterations in cortical excitability during pain: A combined TMS-EEG Study
Chowdhury, N. S.; Chiang, A. K.; Millard, S. K.; Skippen, P.; Chang, W.-J.; Seminowicz, D. A.; Schabrun, S. M.
10.1101/2023.04.20.537735 — neuroscience — Posted on 2023-08-07
3658 A single-cell transcriptomic analysis of the mouse hippocampus after voluntary exercise
Methi, A.; Islam, M. R.; Kaurani, L.; Sakib, M. S.; Krüger, D. M.; Burkhardt, S.; Liebetanz, D.; Fischer, A.
10.1101/2023.08.03.551761 — neuroscience — Posted on 2023-08-07
3662 Engineering the highly productive cyanobacterium Synechococcus sp. PCC 11901
Victoria, A. J.; Selao, T. T.; Moreno-Cabezuelo, J. A.; Mills, L. A.; Gale, G. A.; Lea-Smith, D. J.; McCormick, A. J.
10.1101/2023.08.04.552009 — synthetic biology — Posted on 2023-08-07
3665 Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes
Yan, D.; Hu, B.; Darst, B. F.; Mukherjee, S.; Kunkle, B. W.; Deming, Y.; Dumitrescu, L.; Wang, Y.; Naj, A.; Kuzma, A.; Zhao, Y.; Kang, H.; Johnson, S. C.; Cruchaga, C.; Hohman, T. J.; Crane, P.; Engelman, C. D.; Alzheimer's Disease Genetics Consortium, ; Lu, Q.
10.1101/468306 — genetics — Posted on 2023-08-07
3672 A chromosome-level genome for the nudibranch gastropod Berghia stephanieae helps parse clade-specific gene expression in novel and conserved phenotypes
Goodheart, J. A.; Rio, R. A.; Taraporevala, N. F.; Fiorenza, R. A.; Barnes, S. R.; Morrill, K.; Jacob, M. A. C.; Whitesel, C.; Masterson, P.; Batzel, G. O.; Johnston, H. T.; Ramirez, M. D.; Katz, P. S.; Lyons, D.
10.1101/2023.08.04.552006 — genomics — Posted on 2023-08-06
3673 Matching or genetic engineering of HLA Class I and II facilitates successful allogeneic 'off-the-shelf' regulatory T cell therapy
McCallion, O.; Du, W.; Glaser, V.; Milward, K.; Franke, C.; Kath, J.; Valkov, M.; Yang, M.; Künkele, A.; Polansky, J. K.; Schmueck-Henneresse, M.; Volk, H.-D.; Reinke, P.; Wagner, D. L.; Hester, J.; Issa, F.
10.1101/2023.08.06.551956 — immunology — Posted on 2023-08-06
3674 SynGAP regulates synaptic plasticity and cognition independent of its catalytic activity
Araki, Y.; Rajkovich, K. E.; Gerber, E. E.; Gamache, T. R.; Johnson, R. C.; Tran, T. H.; Liu, B.; Hong, I.; Kirkwood, A.; Huganir, R. L.
10.1101/2023.08.06.552111 — neuroscience — Posted on 2023-08-06
3675 Mucilage produced by sorghum (Sorghum bicolor) aerial roots supports a nitrogen-fixing community
Venado, R. E.; Wilker, J.; Pankievicz, V.; Infante, V.; MacIntyre, A.; Wolf, E.; Vela, S.; Robbins, F. A.; Fernandes-Junior, P. I.; Vermerris, W.; Ane, J.-M.
10.1101/2023.08.05.552127 — plant biology — Posted on 2023-08-06
3676 Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction
Wohlwend, M.; Laurila, P.-P.; Goeminne, L.; Lima, T.; Lalou, A.; Li, X.; von Alvensleben, G.; Crisol, B.; Mangione, R.; Gallart-Ayala, H.; Burri, O.; Butler, S.; Morris, J.; Turner, N.; Ivanisevic, J.; Auwerx, J.
10.1101/2023.08.05.552113 — physiology — Posted on 2023-08-06
3677 Detecting co-selection through excess linkage disequilibrium in bacterial genomes
Mallawaarachchi, S.; Tonkin-Hill, G.; Pöntinen, A. K.; Calland, J. K.; Gladstone, R. A.; Arredondo-Alonso, S.; MacAlasdair, N.; Thorpe, H. A.; Top, J.; Sheppard, S. K.; Balding, D.; Croucher, N. J.; Corander, J.
10.1101/2023.08.04.551407 — bioinformatics — Posted on 2023-08-06
3679 Methods and techniques enabling multi-kilobase long-range genomic rewrite/replace editing
Piggott, C. A.; Tjang, L. V.; Chen, S.; Tatu, U.; Hirou, H.; Jaroszewska, A.; McIntyre, E.; Chen, J.; Faybishenko, J. V.; Gavan, R.; Hackley, C.
10.1101/2023.08.05.551844 — genetics — Posted on 2023-08-06
3685 Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates
Chocarro, J.; Rico, A. J.; Ariznabarreta, G.; Roda, E.; Honrubia, A.; Collantes, M.; Penuelas, I.; Vazquez, A.; Rodriguez-Perez, A. I.; Labandeira-Garcia, J. L.; Vila Bover, M.; Lanciego, J. L.
10.1101/2023.08.04.551615 — neuroscience — Posted on 2023-08-06
3686 YAEL: Your Advanced Electrode Localizer
Wang, Z.; Magnotti, J.; Zhang, X.; Beauchamp, M. S.
10.1101/2023.08.04.552023 — neuroscience — Posted on 2023-08-06
3687 Sex-Specific Developmental Gene Expression Atlas Unveils Dimorphic Gene Networks in C. elegans
Haque, R.; Peedikayil-Kurien, S.; Setty, H.; Salzberg, Y.; Stelzer, G.; Litvak, E.; Gingold, H.; Rechavi, O.; Oren-Suissa, M.
10.1101/2023.08.05.552096 — neuroscience — Posted on 2023-08-06
3689 Tomato Response Evaluation through Fertilization and PGRs application Under Temperature Differentiation in late Winter
Gomasta, J.; Hassan, J.; Sultana, H.; Ozaki, Y.; Alamri, S. A.; Alfagham, A. T.; AL-Humaid, L. A.
10.1101/2023.08.04.552040 — physiology — Posted on 2023-08-06
3693 Unlocking Predictive Power: A Machine Learning Tool Derived from In-Depth Analysis to Forecast the Impact of Missense Variants in Human Filamin C
Nagy, M.; Mlynek, G.; Kostan, J.; Smith, L.; Puehringe, D.; Charron, P.; Rasmussen, T. B.; Bilinska, Z.; Akhtar, M. M.; Syrris, P.; Lopes, L. R.; Elliott, P. M.; Gautel, M.; Carugo, O.; Djinovic-Carugo, K.
10.1101/2023.08.05.552086 — biophysics — Posted on 2023-08-06
3694 Targeted decontamination of sequencing data with CLEAN
Lataretu, M.; Krautwurst, S.; Viehweger, A.; Brandt, C.; Hölzer, M.
10.1101/2023.08.05.552089 — bioinformatics — Posted on 2023-08-06
3697 Phonic Tics in a Rat Model of Tourette Syndrome Enable Research on Symptom-Based DBS
Sagalajev, B.; Lennartz, L.; Mokhtari, N.; Szpak, M.; Schüller, T.; Baldermann, J. C.; Andrade, P.; Visser-Vandewalle, V.; Sesia, T.
10.1101/2023.08.06.551271 — animal behavior and cognition — Posted on 2023-08-06
3698 Leach's Storm-Petrels fledge on the full moon and throughout the lunar cycle
Collins, S. M.; Hedd, A.; Montevecchi, W. A.; Burt, T. V.; Wilson, D. R.; Fifield, D. A.
10.1101/2023.08.04.552000 — animal behavior and cognition — Posted on 2023-08-06
3699 Divergent warning patterns influence male and female mating behaviours in a tropical butterfly
Kuo, C.-Y.; Melo-Flores, L.; Aragon, A.; Oberweiser, M. M.; McMillan, W. O.; Pardo-Diaz, C.; Salazar, C.; Merrill, R. M.
10.1101/2023.08.05.552099 — animal behavior and cognition — Posted on 2023-08-06
3701 Woody plant taxonomic, functional, and phylogenetic diversity decrease along elevational gradients in Andean tropical montane forests: environmental filtering and arrival of temperate taxa
Banares-de-Dios, G.; Macia, M. J.; Arellano, G.; Granzow-de la Cerda, I.; Vega-Alvarez, J.; Arnelas, I.; Espinosa, C. I.; Salinas, N.; Cayuela, L.
10.1101/2023.08.05.551864 — ecology — Posted on 2023-08-06
3705 Glioma-neuronal circuit remodeling induces regional immunosuppression
Nejo, T.; Krishna, S.; Jimenez, C.; Yamamichi, A.; Young, J. S.; Lakshmanachetty, S.; Chen, T.; Phyu, S. S. S.; Ogino, H.; Watchmaker, P.; Diebold, D.; Choudhury, A.; Daniel, A. G. S.; Raleigh, D. R.; Hervey-Jumper, S. L.; Okada, H.
10.1101/2023.08.04.548295 — cancer biology — Posted on 2023-08-06
3706 A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma
Achom, M.; Sadagopan, A.; Bao, C.; McBride, F.; Xu, Q.; Konda, P.; Tourdot, R. W.; Li, J.; Nakhoul, M.; Gallant, D.; Ahmed, U. A.; O'Toole, J.; Freeman, D.; Lee, G.-S. M.; Hecht, J.; Kauffman, E.; Einstein, D. J.; Choueiri, T. K.; Zhang, C.-Z.; Viswanathan, S. R.
10.1101/2023.08.04.552029 — cancer biology — Posted on 2023-08-06
3712 Selective ablation of thymic and peripheral Foxp3+ regulatory T cell development
Yilmazer, A.; Zevla, D. M.; Malmkvist, R.; Bello Rodriguez, C. A.; Undurraga, P.; Kirgin, E.; Boernert, M.; Voehringer, D.; Kershaw, O.; Schlenner, S.; Kretschmer, K.
10.1101/2023.08.04.551974 — immunology — Posted on 2023-08-06
3715 Comprehensive Assessment of Isoform Detection Methods for Third-Generation Sequencing Data
Su, Y.; Yu, Z.; Jin, S.; Ai, Z.; Yuan, R.; Chen, X.; Xue, Z.; Guo, Y.; Chen, D.; Liang, H.; Liu, Z.; Liu, W.
10.1101/2023.08.03.551905 — bioinformatics — Posted on 2023-08-06
3720 Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine
Sun, W.; Winnubst, J.; Natrajan, M.; Lai, C.; Kajikawa, K.; Michaelos, M.; Gattoni, R.; Fitzgerald, J. E.; Spruston, N.
10.1101/2023.08.03.551900 — neuroscience — Posted on 2023-08-06
3721 Reusable, flexible, and lightweight chronic implants for Neuropixels probes
Bimbard, C.; Takacs, F.; Fabre, J. M.; Melin, M. D.; O'Neill, N.; Robacha, M.; Street, J. S.; van Beest, E. H.; Churchland, A. K.; Harris, K. D.; Kullmann, D. M.; Lignani, G.; Carandini, M.; Coen, P.
10.1101/2023.08.03.551752 — neuroscience — Posted on 2023-08-06
3723 Revealing Shared Proteins and Pathways in Cardiovascular and Cognitive Diseases Using Protein Interaction Network Analysis
Zeylan, M. E.; Senyuz, S.; Picon-Pages, P.; Garcia-Elias, A.; Tajes, M.; Munoz, F.; Oliva, B.; Garcia-Ojalvo, J.; Barbu, E.; Vicente, R.; Nattel, S.; Ois-Santiago, A.; Puig-Pijoan, A.; Keskin, O.; Gursoy, A.
10.1101/2023.08.03.551914 — systems biology — Posted on 2023-08-06
3724 Engineering the highly productive cyanobacterium Synechococcus sp. PCC 11901
Victoria, A. J.; Selao, T. T.; Moreno-Cabezuelo, J. A.; Mills, L. A.; Gale, G. A.; Lea-Smith, D. J.; McCormick, A. J.
10.1101/2023.08.04.552009 — synthetic biology — Posted on 2023-08-06
3725 Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice
WADA, I.; Mori, K.; Sreekumar, P. G.; Ji, R.; Spee, C.; Hone, E.; Ishikawa, K.; Sonoda, K.-H.; Kannan, R.
10.1101/2023.08.04.552052 — pathology — Posted on 2023-08-06
3726 Ultrasound Imaging Enables Longitudinal Tracking of Vascular Changes that Correlate with Immune Cell Infiltration After Radiotherapy
Martello, S. E.; Xia, J.; Kusunose, J.; Hacker, B. C.; Mayeaux, M. A.; Lin, E. J.; Hawkes, A.; Singh, A.; Caskey, C. F.; Rafat, M.
10.1101/2023.08.04.552076 — cancer biology — Posted on 2023-08-06
3727 Loss of Polycomb Repressive Complex 2 function causes asparaginase resistance in T-acute lymphoblastic leukemia through decreased WNT pathway activity
Lefeivre, T.; Tudose, C.; Grosu, T.-I.; Jones, L.; Leon, T.; Wynne, K.; Oliviero, G.; Smith, O.; Trinquand, A.; Mansour, M.; Ryan, C.; Bond, J.
10.1101/2023.08.04.552014 — cancer biology — Posted on 2023-08-06
3729 Bulky glycocalyx drives cancer invasiveness by modulating substrate-specific adhesion
Barai, A.; Piplani, N.; Gomathi, V.; Ghogale, M. M.; Kumar, S.; Kulkarni, M.; Sen, S.
10.1101/2023.08.03.551677 — cancer biology — Posted on 2023-08-06
3733 Allergic inflammation triggers dyslipidemia via IgG signalling
Fernandez-Gallego, N.; Castillo-Gonzalez, R.; Moreno-Serna, L.; Garcia-Civico, A. J.; Sanchez-Martinez, E.; Lopez-Sanz, C.; Fontes, A. L.; Pimentel, L. L.; Gradillas, A.; Obeso, D.; Ramirez-Huesca, M.; Ruiz-Fernandez, I.; Nunez-Borque, E.; Carrasco, Y. R.; Ibanez, B.; Martin, P.; Blanco, C.; Barbas, C.; Barber, D.; Rodriguez-Alcala, L. M.; Villasenor, A.; Esteban, V.; Sanchez-Madrid, F.; Jimenez-Saiz, R.
10.1101/2023.08.04.551996 — immunology — Posted on 2023-08-06
3734 A special role for Anterior Cingulate Cortex, but not Orbitofrontal Cortex or Basolateral Amygdala, in choices involving information
Gonzalez, V. V.; Ashikyan, S. A.; Zhang, Y.; Rickard, A.; Yassine, I.; Romero-Sosa, J. L.; Blaisdell, A. P.; Izquierdo, A.
10.1101/2023.08.03.551514 — neuroscience — Posted on 2023-08-06
3735 Restoration of locomotor function following stimulation of the A13 region in Parkinson's mouse models
Kim, L. H.; Lognon, A.; Sharma, S. S.; Tran, M. A.; Chomiak, T.; Tam, S.; McPherson, C.; Eaton, S. E.; Kiss, Z. H.; Whelan, P.
10.1101/2023.08.03.551564 — neuroscience — Posted on 2023-08-06
3736 Impacts of early exposure to ethanol on adenosine functioning in zebrafish
Couto, G. T.; Silva, G. P.; Rockenbach, L.; Silva, J. S.; Vianna, M. R.; Da Silva, R. S.
10.1101/2023.08.03.551856 — neuroscience — Posted on 2023-08-06
3738 A semi-automated method for quantifying optokinetic reflex tracking acuity
Kiraly, J. K.; Harris, S. C.; Al-Khindi, T.; Dunn, F.; Kolodkin, A. L.
10.1101/2023.08.03.551461 — neuroscience — Posted on 2023-08-06
3741 An end-to-end workflow for non-destructive 3D pathology
Bishop, K. W.; Barner, L. A. E.; Han, Q.; Baraznenok, E.; Lan, L.; Poudel, C.; Gao, G.; Serafin, R. B.; Chow, S. S. L.; Glaser, A. K.; Janowczyk, A.; Brenes, D.; Huang, H.; Miyasato, D.; True, L. D.; Kang, S.; Vaughan, J. C.; Liu, J. T. C.
10.1101/2023.08.03.551845 — pathology — Posted on 2023-08-06
3742 Compound activity prediction with dose-dependent transcriptomic profiles and deep learning
Godinez, W. J.; Trifonov, V.; Fang, B.; Kuzu, G.; Pei, L.; Guiguemde, W. A.; Martin, E. J.; King, F. J.; Jenkins, J. L.; Skewes-Cox, P.
10.1101/2023.08.03.551883 — bioinformatics — Posted on 2023-08-06
3748 Non-target Analysis of Wastewater Treatment Plant Effluents: Chemical Fingerprinting as a Monitoring Tool.
Aggerbeck, M. R.; Froekjaer, E. E.; Johansen, A.; Ellegaard-Jensen, L.; Hansen, L. H.; Hansen, M.
10.1101/2023.08.03.551870 — ecology — Posted on 2023-08-06
3751 Decrease in reaction time for volleyball athletes during saccadic eye movement task: An associative analysis with evoked potentials
Costa, E.; Gongora, M.; Bittencourt, J.; Marinho, V.; Cagy, M.; Teixeira, S.; Nicoliche, E.; Fernandes, I.; Wienecke, J.; Ribeiro, P.; Gupta, D.; Velasques, B.; Budde, H.
10.1101/2023.08.03.551793 — neuroscience — Posted on 2023-08-06
3754 DISCOVER-EEG: an open, fully automated EEG pipeline for biomarker discovery in clinical neuroscience
Gil Avila, C.; Bott, F. S.; Tiemann, L.; Hohn, V. D.; May, E. S.; Nickel, M. M.; Zebhauser, P. T.; Gross, J.; Ploner, M.
10.1101/2023.01.20.524897 — neuroscience — Posted on 2023-08-06
3755 NaV1.6 inhibition drives the efficacy of voltage-gated sodium channel inhibitors to prevent electrically induced seizures in both wild type and Scn8aN1768D/+ gain-of-function mice
Johnson, J.; Focken, T.; Tari, P. K.; Dube, C.; Goodchild, S. J.; Andrez, J.-C.; Bankar, G.; Burford, K.; Chang, E.; Chowdhury, S.; Christabel, J.; Dean, R. A.; de Boer, G.; Dehnhardt, C.; Gong, W.; Grimwood, M.; Hussainkhel, A.; Jia, Q.; Khakh, K.; Lee, S.; Li, J.; Lin, S.; Lindgren, A.; Lofstrand, V.; Mezeyova, J.; Nelkenbrecher, K.; Shuart, N. G.; Sojo, L.; Sun, S.; Waldbrook, M.; Wesolowski, S.; Wilson, M.; Xie, Z.; Zenova, A.; Zhang, W.; Scott, F.; Cutts, A. J.; Sherrington, R. P.; Winquist, R.; Cohen, C. J.; Empfield, J. R.
10.1101/2023.08.03.551823 — pharmacology and toxicology — Posted on 2023-08-06
3759 Ribosomal DNA copy number is associated with body mass in humans and other mammals
Law, P. P.; Rodriguez-Algarra, F.; Asenius, F.; Gregori, M.; Seabourne, R. A.; Yildizoglu, S.; Miller, J. R.; Mesnage, R.; Antoniou, M.; Li, W.; Tan, Q.; Hillman, S.; Rakyan, V. K.; Williams, D. J.; Holland, M. L.
10.1101/2023.08.03.551775 — genomics — Posted on 2023-08-06
3760 A transmission bottleneck for malaria? Quantification of sporozoite expelling from laboratory and natural P. falciparum infections
Andolina, C.; Graumans, W.; Guelbeogo, M.; Gemert, G.-J. v.; Ramjith, J.; Harouna, S.; Soumanaba, Z.; Stoter, R.; van de Vegte-Bolmer, M.; Pangos, M.; Sinnis, P.; Collins, K.; Staedke, S.; Tiono, A.; Drakeley, C.; Lanke, K.; Bousema, T.
10.1101/2023.08.03.551751 — microbiology — Posted on 2023-08-06
3761 Lack of p38 activation in T cells increases IL-35 production and protects against obesity by promoting thermogenesis
Nikolic, I.; Ruiz-Garrido, I.; Crespo, M.; Romero-Becerra, R.; Leiva-Vega, L.; Mora, A.; Leon, M.; Rodriguez, E.; Leiva, M.; Plata-Gomez, A. B.; Alvarez, M. B.; Torres, J. L.; Hernandez-Cosido, L.; Lopez, J. A.; Vazquez, J.; Efeyan, A.; Martin, P.; Marcos, M.; Sabio, G.
10.1101/2023.08.04.551982 — immunology — Posted on 2023-08-06
3763 MEK inhibition enhances the antitumor effect of radiation therapy in NF1-deficient glioblastoma
Ioannou, M.; Lalwani, K.; Ayanlaja, A. A.; Chinnasamy, V.; Pratilas, C. A.; Schreck, K. C.
10.1101/2023.08.04.552061 — cancer biology — Posted on 2023-08-06
3768 Topological stress triggers difficult-to-repair DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment
Hornofova, T.; Urbancokova, A.; Novak, J.; Salajkova, S.; Stemberkova Hubackova, S.; Uvizl, A.; Mac Stay, B.; Hodny, Z.; Bartek, J.; Vasicova, P.
10.1101/2023.08.05.552131 — cell biology — Posted on 2023-08-06
3771 Enterovirus-A71 exploits Rab11 to recruit chaperones for virus morphogenesis
NG, Q. Y.; MAHENDRAN, V.; LIM, Z. Q.; Chu, J. J.-H.; Chow, V. T. K.; Sze, N.; Alonso, S.
10.1101/2023.08.05.552141 — microbiology — Posted on 2023-08-06
3773 Accelerated social representational drift in the nucleus accumbens in a model of autism
Zhao, P.; Chen, X.; Bellafard, A.; Murugesan, A.; Quan, J.; Aharoni, D.; Golshani, P.
10.1101/2023.08.05.552133 — neuroscience — Posted on 2023-08-06
3774 Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders
Hiramoto, T.; Sumiyoshi, A.; Kato, R.; Yamauchi, T.; Kang, G.; Matsumura, B.; Stevens, L. J.; Ryoke, R.; Nonaka, H.; Machida, A.; Nomoto, K.; Mogi, K.; Hiroi, Y. J.; Kikusui, T.; Kawashima, R.; Hiroi, N.
10.1101/2023.06.14.545013 — neuroscience — Posted on 2023-08-06
3775 Determining the shelf life of an erythropoietin alfa biosimilar GBPD002 through stability study
Nag, K.; Mohiuddin, M.; Kumar, S.; Khan, M. M. R.; Sarker, M. E. H.; Biswas, B. K.; Roy, R.; Molla, M. T.; Roy, R.; Bappi, M. E. H.; Rahman, A.; Haq, S. R.; Sarker, M. S.; Popy, P. M.; Mumu, R. F.; Barman, U.; Oli, M. S. K.; Khoka, M. S. H.; Sarker, S.; Alam, M. F.; Sultana, N.
10.1101/2023.08.05.552105 — pharmacology and toxicology — Posted on 2023-08-06
3778 Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks
Magnard, R.; Fouyssac, M.; Vachez, Y. M.; Cheng, Y.; Dufourd, T.; Carcenac, C.; Boulet, s.; Janak, P. H.; Savasta, M.; Belin, D.; Carnicella, S.
10.1101/2023.02.05.527198 — neuroscience — Posted on 2023-08-05
3780 Generalizable links between symptoms of borderline personality disorder and functional connectivity
Shafiei, G.; Keller, A. S.; Bertolero, M.; Shanmugan, S.; Bassett, D. S.; Chen, A. A.; Covitz, S.; Houghton, A.; Luo, A.; Mehta, K.; Salo, T.; Shinohara, R. T.; Fair, D.; Hallquist, M. N.; Satterthwaite, T. D.
10.1101/2023.08.03.551534 — neuroscience — Posted on 2023-08-06
3783 Disorganization of basement membrane zone architecture causes impaired melanocyte inhabitation in vitiligo
Yang, F.; Yang, L.; Kuroda, Y.; Lai, S.; Takahashi, Y.; Sayo, T.; Namiki, T.; Nakajima, K.; Sano, S.; Inoue, S.; Tsuruta, D.; Katayama, I.
10.1101/2022.12.18.520911 — pathology — Posted on 2023-08-05
3784 Social attention across development in common ravens and carrion crows
Miller (Harrison), R.; Boeckle, M.; Ridgway, S.; Richardson, J.; Uhl, F.; Bugnyar, T.; Schwab, C.
10.1101/2023.08.03.551806 — animal behavior and cognition — Posted on 2023-08-05
3785 Model-based inference of RNA velocity modules improves cell fate prediction
Aivazidis, A.; Memi, F.; Kleshchevnikov, V.; Clarke, B.; Stegle, O.; Bayraktar, O.
10.1101/2023.08.03.551650 — genomics — Posted on 2023-08-05
3788 A genome-wide cytotoxicity screen of Cluster F1 mycobacteriophage Girr reveals novel inhibitors of Mycobacterium smegmatis growth
Pollenz, R. S.; Barhnhill, K.; Biggs, A.; Bland, J.; Carter, V.; Chase, M.; Clark, H.; Coleman, C.; Daffner, M.; Deam, C.; Finocchiaro, A.; Franco, V.; Fuller, T.; Pinera, J. G.; Horne, M.; Howard, Z.; Kanahan, O.; Miklaszewski, C.; Miller, S.; Morgan, R.; Onalaja, O.; Otero, L.; Padhye, S.; Rainey, E.; Rasul, F.; Robichaux, K.; Rodier, A.; Schlosser, S.; Sciacchitano, A.; Stewart, E.; Thakkar, R.; Heller, D.
10.1101/2023.08.04.552056 — microbiology — Posted on 2023-08-05
3792 Molecular pharmacology of selective NaV1.6 and dual NaV1.6 and NaV1.2 channel inhibitors that suppress excitatory neuronal activity ex vivo
Goodchild, S. J.; Shuart, N. G.; Williams, A. D.; Ye, W.; Parrish, R. R.; Soriano, M.; Thouta, S.; Mezeyova, J.; Waldbrook, M.; Dean, R. A.; Focken, T.; Ghovanloo, M.-R.; Ruben, P. C.; Scott, F.; Cohen, C. J.; Empfield, J. R.; Johnson, J.
10.1101/2023.08.03.551643 — pharmacology and toxicology — Posted on 2023-08-05
3796 Methods for constructing and evaluating consensus genomic interval sets
Rymuza, J.; Sun, Y.; Zheng, G.; LeRoy, N. J.; Murach, M.; Phan, N.; Zhang, A.; Sheffield, N. C.
10.1101/2023.08.03.551899 — genomics — Posted on 2023-08-05
3797 EpiVar Browser: advanced exploration of epigenomics data under controlled access
Lougheed, D. R.; Liu, H.; Aracena, K. A.; Gregoire, R.; Pacis, A.; Pastinen, T.; Barreiro, L. B.; Joly, Y.; Bujold, D.; Bourque, G.
10.1101/2023.08.03.551309 — genomics — Posted on 2023-08-05
3798 KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster
Singh, M.; Spendlove, S.; Wei, A.; Nava, A. A.; Bondhus, l. A.; N. de L. Vitorino, F.; Gomez, D.; Lee, J.; Echeverria, G.; Amano, S.; Garcia, B.; Arboleda, V. A.
10.1101/2023.08.03.550595 — genomics — Posted on 2023-08-05
3802 Investigating the phylogenetic history of toxin tolerance in mushroom-feeding Drosophila
Erlenbach, T.; Haynes, L.; Fish, O.; Beveridge, J.; Bingolo, E.; Giambrone, S.-A.; Kropelin, G.; Rudisill, S.; Chialvo, P.; Reed, L.; Dyer, K.; Chialvo, C. S.
10.1101/2023.08.03.551872 — evolutionary biology — Posted on 2023-08-05
3805 Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses
Jeyachandran, A. V.; Irudayam, J. I.; Dubey, S.; Chakravarty, N.; Konda, B.; Shah, A.; Su, B.; Wang, C.; Cui, Q.; Williams, K. J.; Srikanth, S.; Shi, Y.; Deb, A.; Damoiseaux, R.; Stripp, B.; Ramaiah, A.; Arumugaswami, V.
10.1101/2023.08.04.552083 — microbiology — Posted on 2023-08-05
3806 Nitrite secretion by cyanobacteria is controlled by the small protein NirP1
Kraus, A.; Spaet, P.; Timm, S.; Wilson, A.; Schumann, R.; Hagemann, M.; Macek, B.; Hess, W. R.
10.1101/2023.08.04.552085 — microbiology — Posted on 2023-08-05
3807 Solution structure and synaptic analyses reveal molecular mechanisms of bispecific T cell engagers
Staufer, O.; Leithner, A.; Liberta, F.; Zhou, S.; Schiele, F.; Reindl, S.; Nar, H.; Hoerer, S.; Crames, M.; Comeau, S.; Young, D.; Low, S.; Jenkins, E.; Davis, S. J.; Klenerman, D.; Nixon, A.; Pefaur, N.; Wyatt, D.; Kasturirangan, S.; Dustin, M. L.
10.1101/2022.06.15.496334 — immunology — Posted on 2023-08-05
3809 Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus
Wilmot, J. H.; Diniz, C. R. A. F.; Crestani, A. P.; Puhger, K.; Roshgadol, J.; Tian, L.; Wiltgen, B. J.
10.1101/2022.10.17.512590 — neuroscience — Posted on 2023-08-05
3813 Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions
Edwards, F.; Fantozzi, G.; Simon, A. Y.; Morretton, J.-P.; Herbette, A.; Tijhuis, A. E.; Wardenaar, R.; Foulane, S.; Gemble, S.; Spierings, D. C. J.; Foijer, F.; Mariani, O.; Vincent-Salomon, A.; Roman-Roman, S.; Sastre-Garau, X.; Goundiam, O.; Basto, R.
10.1101/2023.07.28.550973 — cell biology — Posted on 2023-08-05
3817 Genetic Dependence and Genetic Diseases
Li, B.; Bian, W.-J.; Zhou, P.; Wang, J.; Fan, C.-X.; Xu, H.-Q.; Yu, L.; He, N.; Shi, Y.-W.; Su, T.; Yi, Y.-H.; Liao, W.-P.
10.1101/2023.08.02.551736 — genetics — Posted on 2023-08-05
3820 A single-cell transcriptomic analysis of the mouse hippocampus after voluntary exercise
Methi, A.; Islam, M. R.; Kaurani, L.; Sakib, M. S.; Krueger, D. M.; Burkhardt, S.; Liebetanz, D.; Fischer, A.
10.1101/2023.08.03.551761 — neuroscience — Posted on 2023-08-05
3822 Single-cell analysis characterizes PLK1 as a promoter of immunosuppressive tumor microenvironment in LUAD
Kong, Y.; Li, C.; Liu, J.; Zhang, M.; Allison, D. B.; Hassan, F.; He, D.; Wang, X.; Mao, F.; Zhang, Q.; Zhang, Y.; Li, Z.; Wu, S.; Wang, C.; Liu, X.
10.1101/2023.08.02.551692 — cancer biology — Posted on 2023-08-05
3823 Selective elimination of CD169+ macrophages in lymph nodes invaded by breast cancers
Maeshima, Y.; Kataoka, T. R.; Vandenbon, A.; Hirata, M.; Takeuchi, Y.; Suzuki, Y.; Fukui, Y.; Ibi, Y.; Haga, H.; Morita, S.; Toi, M.; Kawaoka, S.; Kawaguchi, K.
10.1101/2023.08.02.551659 — cancer biology — Posted on 2023-08-05
3824 Forward genetic screening in engineered colorectal cancer organoids identifies novel regulators of metastasis
Cramer, Z.; Wang, X.; Leu, N. A.; Monaghan, K.; Rhoades, J. H.; Tian, Y.; Rico, J.; Mendez, D.; Petroni, R.; Kim, M. S.; Matsuda, R.; Carrera, M. F.; Brodsky, I. E.; Li, N.; Lengner, C. J.; Blanco, M. A.
10.1101/2023.08.03.551805 — cancer biology — Posted on 2023-08-05
3826 Estimating the reproduction number, R0, from agent-based models of tree disease spread
Wadkin, L. E.; Holden, J.; Ettelaie, R.; Holmes, M. J.; Smith, J.; Golightly, A.; Parker, N. G.; Baggaley, A. W.
10.1101/2023.08.03.551748 — ecology — Posted on 2023-08-05
3827 TRAFfic signals: High-throughput CAR discovery in NK cells reveals novel TRAF-binding endodomains that drive enhanced persistence and cytotoxicity
Williams, M. D.; Chen, A. T.; Stone, M. R.; Guo, L.; Belmont, B. J.; Turk, R.; Bogard, N.; Kearns, N.; Young, M.; Daines, B.; Darnell, M.
10.1101/2023.08.02.551530 — immunology — Posted on 2023-08-05
3828 TIM3 is a context-dependent co-regulator of cytotoxic T cell function
Alamir, H.; Wong, C. W. C.; Alsubaiti, A.; Edmunds, G. L.; Grant, T.; Alsulaimani, S.; Boyd, J.; Holland, C. J.; Morgan, D. J.; Gallimore, A. M.; Wuelfing, C.
10.1101/2023.08.03.551797 — immunology — Posted on 2023-08-05
3830 The genomes and epigenomes of aquatic plants (Lemnaceae) promote triploid hybridization and clonal reproduction
Ernst, E.; Abramson, B.; Acosta, K.; Hoang, P. T.; Mateo-Elizalde, C.; Schubert, V.; Pasaribu, B.; Hartwick, N.; Colt, K.; Aylward, A. J.; Ramu, U.; Birchler, J. A.; Schubert, I.; Lam, E.; Michael, T. P.; Martienssen, R. A.
10.1101/2023.08.02.551673 — plant biology — Posted on 2023-08-05
3831 An Integrated Platform for in vivo Electrophysiology in Spatial Cognition Experiments
Brea Guerrero, A.; Oijala, M.; Moseley, S. C.; Tang, T.; Fletcher, F.; Zheng, Y.; Sanchez, L. M.; Clark, B.; Mcnaughton, B.; Wilber, A. A.
10.1101/2023.08.02.551691 — animal behavior and cognition — Posted on 2023-08-05
3835 CONDITIONALLY MUTANT ANIMAL MODEL FOR INVESTIGATING THE INVASIVE TROPHOBLAST CELL LINEAGE
Iqbal, K.; Nixon, B.; Crnkovich, B.; Dominguez, E. M.; Moreno Irusta, A.; Scott, R. L.; vu, h.; Tuteja, G.; Vivian, J. L.; Soares, M.
10.1101/2023.08.02.551740 — developmental biology — Posted on 2023-08-05
3836 Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons
Perez, C. I.; Luis-Islas, J.; Lopez, A.; Diaz, X.; Molina, O.; Arroyo, B.; Moreno, M. G.; Lievana, E. G.; Fonseca, E.; Castaneda-Hernandez, G.; Gutierrez, R.
10.1101/2023.08.02.551706 — neuroscience — Posted on 2023-08-05
3838 Improving rigor and reproducibility in western blot experiments with the blotRig analysis software
Omondi, C.; Chou, A.; Fond, K. A.; Morioka, K.; Joseph, N. R.; Sacramento, J. A.; Lorio, E.; Torres-Espin, A.; Radabaugh, H. L.; Davis, J. A.; Gumbel, J. H.; Huie, J. R.; Ferguson, A. R.
10.1101/2023.08.02.551674 — neuroscience — Posted on 2023-08-05
3839 Prevalence of mango postharvest Stem-end rot disease in Cote d'Ivoire and identification of fungal pathogens associated
Yeo, Y. S.; KONE, Y.; DEMBELE, D. D.; Amari, G. E.; Rey, J.-Y.; Del Ponte, E. M.; Fernandez, D.; KONE, D.
10.1101/2023.08.02.551668 — plant biology — Posted on 2023-08-05
3840 Direct photoreception of a pituitary endocrine cell, melanotroph, induces a hormone release
Fukuda, A.; Sato, K.; Fujimori, C.; Yamashita, T.; Takeuchi, A.; Ohuchi, H.; Umatani, C.; Kanda, S.
10.1101/2023.08.02.551597 — physiology — Posted on 2023-08-05
3843 Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts
Sychev, Z. E.; Day, A.; Bergom, H. E.; Larson, G.; Ali, A.; Ludwig, M.; Boytim, E.; Ilsa, C.; Corey, E.; Plymate, S. R.; Nelson, P. S.; Hwang, J. H.; Drake, J. M.
10.1101/2023.08.02.551697 — cancer biology — Posted on 2023-08-05
3849 Declines in ice cover induce light limitation in freshwater diatoms
Zepernick, B. N.; Chase, E. E.; Denison, E. R.; Gilbert, N. E.; Martin, R. M.; Truchon, A. R.; Frenken, T.; Cody, W. R.; Chaffin, J. D.; Bullerjahn, G. S.; McKay, R. M.; Wilhelm, S. W.
10.1101/2023.08.02.551672 — ecology — Posted on 2023-08-05
3850 High-temporal resolution functional PET/MRI reveals coupling between human metabolic and hemodynamic brain response
Hahn, A.; Reed, M. B.; Vraka, C.; Godbersen, G. M.; Klug, S.; Komorowski, A.; Falb, P.; Nics, L.; Traub-Weidinger, T.; Hacker, M.; Lanzenberger, R.
10.1101/2023.08.02.551631 — neuroscience — Posted on 2023-08-05
3852 Self-regulation of attention in children in a virtual classroom environment: a feasibility study
Guedj, C.; Tyrand, R.; Badier, E.; Planchamp, L.; Stringer, M.; Zimmermann, M. O.; Ferat, V.; Ha-Vinh Leuchter, R.; Grouiller, F.
10.1101/2023.08.02.551583 — neuroscience — Posted on 2023-08-05
3856 Multi-representation DeepInsight: an improvement on tabular data analysis
Sharma, A.; Lopez, Y.; JIA, S.; Lysenko, A.; Boroevich, K.; Tsunoda, T.
10.1101/2023.08.02.551620 — bioinformatics — Posted on 2023-08-05
3859 Chrombus-XMBD: A Graph Generative Model Predicting 3D-Genome, ab initio from Chromatin Features
Zeng, Y.; You, Z.; Guo, J.; Zhao, J.; Zhou, Y.; Huang, J.; Lyu, X.; Chen, L.; Li, Q.
10.1101/2023.08.02.551072 — bioinformatics — Posted on 2023-08-05
3862 Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling
Nguyen, H. T. H.; Rissanen, S.-L.; Peltokangas, M.; Laakkonen, T.; Kettunen, J.; Barthod, L.; Sivakumar, R.; Palojarvi, A.; Junttila, P.; Talvitie, J.; Bassis, M.; Nickels, S. L.; Schwamborn, J. C.; Mosser, S.; Singh, P.
10.1101/2023.08.02.551612 — bioengineering — Posted on 2023-08-05
3864 A major endogenous glycosidase mediating quercetin uptake in Bombyx mori
Waizumi, R.; Hirayama, C.; Tomita, S.; Iizuka, T.; Kuwazaki, S.; Jouraku, A.; Tsubota, T.; Yokoi, K.; Yamamoto, K.; Sezutsu, H.
10.1101/2023.08.02.551622 — genetics — Posted on 2023-08-05
3868 Analytical code sharing practices in biomedical research
Sharma, N. K.; Ayyala, R.; Deshpande, D.; Patel, Y. M.; Munteanu, V.; Ciorba, D.; Fiscutean, A.; Vahed, M.; Sarkar, A.; Guo, R.; Moore, A.; Darci-Maher, N.; Nogoy, N. A.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2023.07.31.551384 — scientific communication and education — Posted on 2023-08-05
3869 Resident memory T cell precursors in tumor draining lymph nodes require type-1 IFN for optimal differentiation
Khatwani, N.; Searles, T.; Han, J.; Messier, C.; Mittal, N.; Molodtsov, A.; Ramirez, D.; Hawkes, A.; Williams, O. M.; Huang, Y. H.; Kolling, F. W.; Rosato, P.; Turk, M. J.
10.1101/2023.08.02.551658 — immunology — Posted on 2023-08-05
3870 Ablation of carotid body activity reverses diabesity by improving white and brown adipose tissue sympathetic innervation and metabolism
Melo, B. F.; Sacramento, J. F.; Lavergne, J.; Martins, F. O.; Rosendo-Silva, D.; Panzolini, C.; Melo, G. M.; Prego, C. S.; Falvey, A.; Olea, E.; Matafome, P.; Rocher, A.; Prieto-Lloret, J.; Correia, M. C.; Blancou, P.; Conde, S. V.
10.1101/2023.08.04.552063 — physiology — Posted on 2023-08-05
3872 Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation
Elkholi, I. E.; Robert, A.; Kuasne, H.; Drapela, S.; Macleod, G.; Hebert, S.; Pacis, A.; Calderon, V.; Kleinman, C. L.; Gomes, A. P.; Aguirre-Ghiso, J. A.; Park, M.; Angers, S.; Cote, J.-F.
10.1101/2023.08.02.551681 — cancer biology — Posted on 2023-08-05
3873 SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy
Dembitz, V.; Lawson, H.; Burt, R.; Philippe, C.; James, S. C.; Atkinson, S.; Durko, J.; Wang, L. M.; Campos, J.; Magee, A. M.; Woodley, K.; Austin, M. J.; Rio-Machin, A.; Casado-Izquierdo, P.; Bewicke-Copley, F.; Rodriguez, G.; Pereira, D.; Oudejans, L.; Boet, E.; von Kriegsheim, A.; Schwaller, J.; Finch, A. J.; Pate, B.; Sarry, J.-E.; Tamburini, J.; Schuringa, J. J.; Hazlehurst, L.; Copland, J. A.; Yuneva, M.; Peck, B.; Cutillas, P.; Fitzgibbon, J.; Rouault-Pierre, K.; Kranc, K.; Gallipoli, P.
10.1101/2023.08.02.551656 — cancer biology — Posted on 2023-08-05
3874 Solution structure and synaptic analyses reveal molecular mechanisms of T cell specific engagers
Staufer, O.; Leithner, A.; Liberta, F.; Zhou, S.; Schiele, F.; Reindl, S.; Nar, H.; Hoerer, S.; Crames, M.; Comeau, S.; Young, D.; Low, S.; Jenkins, E.; Davis, S. J.; Klenerman, D.; Nixon, A.; Pefaur, N.; Wyatt, D.; Kasturirangan, S.; Dustin, M. L.
10.1101/2022.06.15.496334 — immunology — Posted on 2023-08-05
3875 Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation.
Hadebe, S.; Savulescu, A. F.; Khumalo, J.; Jones, K.; Mangali, S.; Mthembu, N.; Musaigwa, F.; Maepa, W.; Ndlovu, H.; Ngomti, A.; Scibiorek, M.; Okendo, J.; Brombacher, F.
10.1101/2023.08.02.551636 — immunology — Posted on 2023-08-05
3876 Cellular Senescence Affects ECM Regulation in COPD Lung Tissue
Woldhuis, R. R.; Bekker, N. J.; Nijnatten, J. L. L.; Meuleman, R. A.; Kooistra, W.; Wolters, K. J. C.; Horvatovich, P. L.; Guryev, V.; van den Berge, M.; Timens, W.; Brandsma, C.-A.
10.1101/2023.08.02.551614 — pathology — Posted on 2023-08-05
3879 A hypothalamic node for the cyclical control of female sexual rejection
Gutierrez, N.; Husain, B. F. A.; Dias, I. C.; Nomoto, K.; Duarte, M. A.; Ferreira, L.; Lacoste, B.; Lima, S. Q.
10.1101/2023.01.30.526259 — neuroscience — Posted on 2023-08-05
3880 Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia.
Caiaffa, C. D.; AMBEKAR, Y. S.; Singh, M.; Lin, Y. L.; Wlodarczyk, B.; Aglyamov, S. R.; Scarcelli, G.; Larin, K. V.; Finnell, R.
10.1101/2023.08.04.552068 — developmental biology — Posted on 2023-08-04
3881 Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells
Yao, Y.; Lou, X.; Du, G.; Jin, L.; Li, J.; Liu, J.; Chen, Y.; Cheng, S.; Zhao, T.; Ke, S.; Zhang, L.; Zhang, P.; Xu, Y.; He, L.; Li, H.
10.1101/2023.08.03.551799 — cell biology — Posted on 2023-08-04
3883 hGRAD - a versatile 'one-fits-all' system for the acute depletion of RNA binding proteins in nuclear condensates
Muller-McNicoll, M.; Zarnack, K.; McNicoll, F.; Keller, M.; Sliskovic, I.; Okuda, E. K.; Riegger, R. J.; Arnold, B.
10.1101/2023.08.04.551933 — cell biology — Posted on 2023-08-04
3885 Discovery of a multipotent cell type from the term human placenta
Vadakke-Madathil, S.; Wang, B.; Oniskey, M.; Dekio, F.; Brody, R.; Gelber, S.; Sperling, R.; Chaudhry, H. W.
10.1101/2023.08.02.551028 — cell biology — Posted on 2023-08-04
3886 Correlative single-cell X-ray tomography and X-ray fluorescence imaging
Lin, Z.; Zhang, X.; Nandi, P.; Lin, Y.; Wang, L.; Chu, Y.; Paape, T.; Yang, Y.; Xiao, X.; Liu, Q.
10.1101/2023.08.03.551868 — cell biology — Posted on 2023-08-04
3891 A fibroblast-derived TGFβ/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis
Cohen, M. L.; Brumwell, A. N.; Ho, T. C.; Montas, G.; Golden, J. A.; Jones, K. D.; Wolters, P. J.; Wei, Y.; Chapman, H. A.; Le Saux, C. J.
10.1101/2023.08.02.551383 — cell biology — Posted on 2023-08-05
3898 Ciliary ARL13B prevents obesity in mice
Terry, T. T.; Gigante, E. D.; Alexandre, C. M.; Brewer, K. M.; Engle, S. E.; Yue, X.; Berbari, N. F.; Vaisse, C.; Caspary, T.
10.1101/2023.08.02.551695 — genetics — Posted on 2023-08-04
3900 Resistance and resiliency of soil microbiomes under climate change
Boyle, J. A.; Murphy, B. K.; Ensminger, I.; Stinchcombe, J. R.; Frederickson, M. E.
10.1101/2023.08.04.551981 — ecology — Posted on 2023-08-04
3903 Comprehensive genome editing confers "off-the-shelf" CAR-T cells superior efficacy against solid tumors
Murray, R.; Navarrete, N. R. R.; Desai, K.; Chowdhury, M. R.; Chilakapati, S. R.; Chong, B.; Messana, A.; Sobon, H.; Rocha, J.; Musenge, F.; Camblin, A.; Ciaramella, G.; Sitkovsky, M.; Maldini, C.; Hatfield, S.
10.1101/2023.08.03.551705 — cell biology — Posted on 2023-08-04
3907 Retinoid X Receptor activation prevents diabetic retinopathy in murine models.
Dorofeeva, I.; Zhylkibayev, A.; Saltykova, I. V.; Atigadda, V.; Adhikari, B.; Gorbatyuk, O.; Grant, M. B.; Gorbatyuk, M. S.
10.1101/2023.08.03.551887 — molecular biology — Posted on 2023-08-04
3912 Differential substrate affinity and catabolite repression enable preferential use of urea by ammonia-oxidizing bacteria
Qin, W.; Wei, S. P.; Zheng, Y.; Choi, E.; Li, X.; Johnston, J.; Wan, X.; Abrahamson, B.; Flinkstrom, Z.; Wang, B.; Li, H.; Hou, L.; Tao, Q.; Chlouber, W. W.; Sun, X.; Wells, M.; Ngo, L.; Hunt, K. A.; Urakawa, H.; Tao, X.; Wang, D.; Pan, C.; Weber, P. K.; Jiang, J.; Zhou, J.; Zhang, Y.; Stahl, D. A.; Ward, B. B.; Mayali, X.; Martens-Habbena, W.; Winkler, M.
10.1101/2023.08.04.551995 — microbiology — Posted on 2023-08-04
3917 Pathogen lifestyle defines host genetic signature of quantitative disease resistance in oilseed rape (Brassica napus)
Jacott, C. N.; Schoonbeek, H.-j.; Steuernagel, B.; Kirby, R.; Zheng, X.; von Tiedermann, A.; Macioszek, V. K.; Kononowicz, A. K.; Fell, H.; Fitt, B. D. L.; Mitrousia, G. K.; Stotz, H. U.; Ridout, C. J.; Wells, R.
10.1101/2023.08.02.551671 — plant biology — Posted on 2023-08-04
3918 A Titratable Necrotizing Enterocolitis Mouse Model
Sha, C.; VanBrunt, T.; Kudria, J.; Schmidt, D.; Singh, A.; Bandovic, J.; Giarrizzo, M.; Bialkowska, A. B.; Wollmuth, L.; Speer, E.; Hsieh, H.
10.1101/2023.08.03.551849 — physiology — Posted on 2023-08-04
3919 Interface-guided phenotyping of coding variants in the transcription factor RUNX1 with SEUSS
Ozturk, K.; Panwala, R.; Sheen, J.; Ford, K.; Payne, N.; Zhang, D.-E.; Hutter, S.; Haferlach, T.; Ideker, T.; Mali, P.; Carter, H.
10.1101/2023.08.03.551876 — bioinformatics — Posted on 2023-08-04
3922 Time-resolved X-ray solution scattering unveils the sequence of events leading to human Hb heme capture by Staphylococcus aureus IsdB
De Bei, O.; Marchetti, M.; Guglielmo, S.; Gianquinto, E.; Spyrakis, F.; Campanini, B.; Bettati, S.; Levantino, M.; Ronda, L.
10.1101/2023.08.04.551941 — biochemistry — Posted on 2023-08-04
3923 Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
de Haas, R. J.; Brunette, N.; Goodson, A.; Dauparas, J.; Yi, S. Y.; Yang, E. C.; Dowling, Q.; Nguyen, H.; Kang, A.; Bera, A. K.; Sankaran, B.; de Vries, R.; Baker, D.; King, N. P.
10.1101/2023.08.04.551935 — biochemistry — Posted on 2023-08-04
3924 Using human genetics to develop strategies to increase erythropoietic output from genome-edited hematopoietic stem and progenitor cells
Camarena, J.; Luna, S. E.; Hampton, J. P.; Majeti, K. R.; Charlesworth, C. T.; Soupene, E.; Sheehan, V. A.; Cromer, M. K.; Porteus, M. H.
10.1101/2023.08.04.552064 — genetics — Posted on 2023-08-04
3925 Clr4SUV39H1 ubiquitination and non-coding RNA mediate transcriptional silencing via heterochromatic phase transitions
Kim, H.-S.; Roche, B.; Bhattacharjee, S.; Todeschini, L.; Chang, A.-Y.; Hammell, C.; Verdel, A.; Martienssen, R. A.
10.1101/2021.01.08.425919 — molecular biology — Posted on 2023-08-04
3926 The essential genome of Xanthomonas citri
Wang, X.; Wu, M.; Ge, Y.; Lv, W.; Liu, C.; Ding, X.; Zhang, Y.; Wang, J.; Zhang, Y.; Li, L.; Zhou, X.
10.1101/2023.08.03.551896 — microbiology — Posted on 2023-08-04
3928 Seed or soil: tracing back the plant mycobiota primary sources.
Laurent-Webb, L.; Maurice, K.; Benoit, P.-L.; Amelia, B.; Ducousso, M.; Selosse, M.-A.
10.1101/2023.08.04.551828 — microbiology — Posted on 2023-08-04
3930 Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
Kumar, S.; Singh, S.; Chatterjee, A.; Bajpai, P.; Sharma, S.; Katpara, S.; Lodha, R.; Dutta, S.; Luthra, K.
10.1101/2023.01.19.524673 — immunology — Posted on 2023-08-04
3932 Balance of Activity during a Critical Period Tunes a Developing Network
Hunter, I.; Coulson, B.; Pettini, T.; Davies, J. J.; Parkin, J.; Landgraf, M.; Baines, R. A.
10.1101/2023.08.04.551972 — neuroscience — Posted on 2023-08-04
3933 Sex differences in prenatal development of neural complexity in the human brain
Frohlich, J.; Moser, J.; Sippel, K.; Mediano, P. A. M.; Preissl, H.; Gharabaghi, A.
10.1101/2022.11.21.517302 — neuroscience — Posted on 2023-08-04
3938 Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts
Chapman, N.; Navas, P.; Dorschner, M.; Mehaffey, M.; Wigg, K.; Price, K.; Naumova, O.; Elizabeth, K.; Guger, S.; Lovett, M.; Grigorenko, E.; Berninger, V.; Barr, C.; Wijsman, E.; Raskind, W.
10.1101/2023.08.01.551585 — genetics — Posted on 2023-08-04
3942 Salmonella impairs macrophage immunity through effector-independent rapid translational induction in response to membrane puncture by the SPI-1 injectisome
Wood, G.; Powell, J.; Johnson, R.; Lastovka, F.; Bryant, O.; Brember, M.; Tourlomousis, P.; Carr, J.; Bryant, C.; Chung, B. Y.
10.1101/2023.07.21.550113 — molecular biology — Posted on 2023-08-04
3943 Two circadian oscillators in one cyanobacterium
Koebler, C.; Schmelling, N. M.; Pawlowski, A.; Spaet, P.; Scheurer, N. M.; Sebastian, K.; Berwanger, L.; Macek, B.; Wiegard, A.; Axmann, I. M.; Wilde, A.
10.1101/2021.07.20.453058 — microbiology — Posted on 2023-08-04
3944 Evolution of a Functionally Intact but Antigenically Distinct DENV Fusion Loop
Meganck, R. M.; Zhu, D.; Dong, S.; Snoderly-Foster, L. J.; Dalben, Y. R.; Thiono, D. J.; White, L. J.; DeSilva, A. M.; Baric, R.; Tse, L. V.
10.1101/2023.03.22.533803 — microbiology — Posted on 2023-08-04
3949 Binding of cortical functional modules by synchronous high frequency oscillations
Garrett, J. C.; Verzhbinsky, I. A.; Kaestner, E.; Carlson, C.; Doyle, W. K.; Devinsky, O.; Thesen, T.; Halgren, E.
10.1101/2023.05.20.541597 — neuroscience — Posted on 2023-08-04
3950 CAAStools, a toolbox to identify and test Convergent Amino Acid Substitutions.
Barteri, F.; Valenzuela, A.; Farre, X.; Juan, D.; Muntane, G.; Esteve-Altava, B.; Navarro, A.
10.1101/2022.12.14.520422 — bioinformatics — Posted on 2023-08-04
3951 The effect of information content distributions on word recollection and familiarity
Wallenberg, J. C.; Hinton, T. D.; Smulders, T. V.; Read, J. C. A.; Cuskley, C.; Fadhilah, S. N.
10.1101/2023.08.02.551617 — animal behavior and cognition — Posted on 2023-08-04
3952 Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates axon guidance genes in Drosophila
Singh, B. N.; Tran, H.; Kramer, J.; Kirichenko, E.; Changela, N.; Wang, F.; Feng, Y.; Kumar, D.; Tu, M.; Lan, J.; Bizet, M.; Fuks, F.; Steward, R.
10.1101/2023.01.03.522592 — genomics — Posted on 2023-08-04
3955 The structure of immature tick-borne encephalitis virus
Anastasina, M.; Fuzik, T.; Domanska, A.; Pulkkinen, L. I. A.; Smerdova, L.; Formanova, P. P.; Strakova, P.; Novacek, J.; Ruzek, D.; Plevka, P.; Butcher, S. J.
10.1101/2023.08.04.551633 — microbiology — Posted on 2023-08-04
3959 A comprehensive workflow and its validation for simulating diffuse speckle statistics for optical blood flow measurements
Kobayashi Frisk, L. C.; Verma, M.; Beslija, F.; Lin, C.-H. P.; Patil, N.; Chetia, S.; Trobaugh, J.; Culver, J. P.; Durduran, T.
10.1101/2023.08.03.551830 — bioengineering — Posted on 2023-08-04
3963 Aberrant tissue stiffness impairs neural tube development in Mthfd1l mutant mouse embryos
Ambekar, Y. S.; CAIAFFA, C. D.; Wlodarczyk, B.; Singh, M.; Schill, A. W.; Steele, J.; Aglyamov, S. R.; Scarcelli, G.; Finnell, R. H.; Larin, K. V.
10.1101/2023.08.04.552024 — developmental biology — Posted on 2023-08-04
3964 Optogenetic control of lysosome function
Ilyinsky, N. S.; Bukhalovich, S. M.; Bagaeva, D. F.; Nesterov, S. V.; Alekseev, A. A.; Tsybrov, F. M.; Bogorodskiy, A. O.; Moiseeva, O. V.; Vlasova, A. D.; Kovalev, K. V.; Mikhailov, A. E.; Rogachev, A. V.; Bamberg, E.; Ivanovich, V.; Borshchevskiy, V. I.
10.1101/2023.08.02.551716 — cell biology — Posted on 2023-08-04
3966 The mechanics of bronchoconstriction cause airway epithelial damage and inflammation by excess crowding-induced extrusion
Bagley, D. C.; Russell, T.; Ortiz-Zapater, E.; Fox, K.; Redd, P. F.; Joseph, M.; Rice, C. D.; Reilly, C. A.; Parsons, M.; Rosenblatt, J.
10.1101/2023.08.04.551943 — cell biology — Posted on 2023-08-04
3967 Tight junction membrane proteins regulate the mechanical resistance of the apical junctional complex
Nguyen, T. P.; Otani, T.; Tsutsumi, M.; Fujiwara, S.; Nemoto, T.; Fujimori, T.; Furuse, M.
10.1101/2023.08.02.551232 — cell biology — Posted on 2023-08-04
3968 Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast
Talavera, R. A.; Prichard, B. E.; Sommer, R. A.; Leitao, R. M.; Sarabia, C. J.; Hazir, S.; Paulo, J. A.; Gygi, S.; Kellogg, D.
10.1101/2023.08.04.552008 — cell biology — Posted on 2023-08-04
3970 Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2
Yin, K.; Peluso, M. J.; Luo, X.; Thomas, R.; Shin, M.-G.; Neidleman, J.; Andrew, A.; Young, K.; Ma, T.; Hoh, R.; Anglin, K.; Huang, B.; Argueta, U.; Lopez, M.; Valdivieso, D.; Asare, K.; Deveau, T.-M.; Munter, S. E.; Ibrahim, R.; Standker, L.; Lu, S.; Goldberg, S. A.; Lee, S. A.; Lynch, K. L.; Kelly, J. D.; Martin, J. N.; Muench, J.; Deeks, S. G.; Henrich, T. J.; Roan, N. R.
10.1101/2023.02.09.527892 — immunology — Posted on 2023-08-04
3975 Methanolobus use unspecific methyltransferases to produce methane from dimethylsulfide
Tsola, S. L.; Chen, Y.; Sanders, I. A.; Economou, C. K.; Bruchert, V.; Eyice, O.
10.1101/2023.08.04.551946 — microbiology — Posted on 2023-08-04
3976 Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana
Eger, E.; Homeier-Bachmann, T.; Adade, E.; Dreyer, S.; Heiden, S. E.; Tawiah, P. O.; Sylverken, A. A.; Knauf, S.; Schaufler, K.
10.1101/2023.08.04.551947 — microbiology — Posted on 2023-08-04
3977 Anti-PD-1-iRGD Peptide Conjugate Boosts Antitumor Efficacy via Engagement Augmentation and Penetration Enhancement of T cells
Pan, Y.; Xue, Q.; Yang, Y.; Shi, T.; Wang, H.; Song, X.; Luo, Y.; Liu, B.; Song, Z.; Li, J. P.; Wei, J.
10.1101/2023.08.04.551949 — immunology — Posted on 2023-08-04
3979 Performance and allocation can simultaneously shape behaviour in fire-disturbed populations of root vole
Boratynski, J. S.; Iwinska, K.; Wirowska, M.; Borowski, Z.; Solecki, P.; Ciesielski, M.; Boratynski, Z.
10.1101/2023.08.04.551962 — zoology — Posted on 2023-08-04
3980 Multi-color live-cell optical nanoscopy using phasor analysis
Zhang, Z.; Huang, Y.; Tao, W.; Wei, Y.; Xu, L.; Gong, W.; Zhang, Y.; Han, Y.; Kuang, C.; Liu, X.
10.1101/2023.08.04.551988 — cell biology — Posted on 2023-08-04
3981 Novel mechanisms of MITF regulation and melanoma predisposition identified in a mouse suppressor screen
Vu, H. N.; Valdimarsson, M. M.; Sigurbjornsdottir, S.; Bergsteinsdottir, K.; Debbache, J.; Bismuth, K.; Swing, D. A.; Hallsson, J. H.; Larue, L.; Arnheiter, H.; Copeland, N. G.; Jenkins, N. A.; Heidarsson, P. O.; Steingrimsson, E.
10.1101/2023.08.04.551952 — molecular biology — Posted on 2023-08-04
3982 Genetic crosses within and between species of Cryptosporidium
Shaw, S.; Cohn, I. S.; de Paula Baptista, R.; Xia, G.; Melillo, B.; Agyabeng-Dadzie, F.; Kissinger, J. C.; Striepen, B.
10.1101/2023.08.04.551960 — microbiology — Posted on 2023-08-04
3983 Balance of Activity during a Critical Period Tunes a Developing Network
Hunter, I.; Coulson, B.; Pettini, T.; Davies, J. J.; Parkin, J.; Landgraf, M.; Baines, R. A.
10.1101/2023.08.04.551972 — neuroscience — Posted on 2023-08-04
3985 Is Inappropriate Pulse Timing Responsible for Poor Binaural Hearing with Cochlear Implants?
Schnupp, J. W.; Buchholz, S.; Buck, A. N.; Budig, H. K.; Khurana, L.; Rosskothen-Kuhl, N.
10.1101/2023.08.04.551983 — neuroscience — Posted on 2023-08-04
3988 Gbx2 controls amacrine cell dendrite stratification through Robo1/2 receptors
Kerstein, P. C.; Santana Agreda, Y.; Curran, B. M.; Ma, L.; Wright, K. M.
10.1101/2023.08.03.551861 — neuroscience — Posted on 2023-08-04
3989 Human iPSC-derived neural stem cells display a radial glia-like signature in vitro and favorable long-term safety in transplanted mice
Luciani, M.; Garsia, C.; Beretta, S.; Petiti, L.; Peano, C.; Merelli, I.; Cifola, I.; Miccio, A.; Meneghini, V.; Gritti, A.
10.1101/2023.08.04.551937 — neuroscience — Posted on 2023-08-04
3990 Muscle-restricted Nox4 knockout partially corrects muscle contractility following spinal cord injury in mice
Toro, C. A.; De Gasperi, R.; Aslan, A.; Johnson, N.; Siddiq, M. M.; Chow, C.; Zhao, W.; Harlow, L.; Graham, Z. A.; Liu, X.-H.; Sadoshima, J.; Iyengar, R.; Cardozo, C. P.
10.1101/2023.08.04.551985 — physiology — Posted on 2023-08-04
3992 On Casein Kinase-2 (CK2) deregulation in NSCLC: an enzyme subunit-centered approach
Perez, G. V.; Chen, L.; Chenyi, D.; Ying, Y.; Qiang, Z.; Zhiwei, Z.; Ke, Y.; Perea, S. E.; Perera, Y.
10.1101/2023.08.04.551954 — cancer biology — Posted on 2023-08-04
3993 Neo-epitope identification by weakly-supervised peptide-TCR binding prediction
Gao, Y.; Gao, Y.; Li, W.; Wu, S.; Xing, F.; Zhou, C.; Fu, S.; Chuai, G.; Chen, Q.; Zhang, H.; Liu, Q.
10.1101/2023.08.02.550128 — bioinformatics — Posted on 2023-08-04
3995 Rapid and unbiased enrichment of extracellular vesicles via meticulously engineered peptide
Wang, L.; Gong, Z.; Wang, M.; Liang, Y.-Z.; Zhao, J.; Xie, Q.; Wu, X.-W.; Li, Q.-Y.; Zhang, C.; Ma, L.-Y.; Zheng, S.-Y.; Yu, X.; Xu, L.
10.1101/2023.08.04.551951 — bioengineering — Posted on 2023-08-04
3997 ArreSTick Motif is Responsible for GPCR-beta-Arrestin Binding Stability and Extends Phosphorylation-Dependent beta-arrestin Interactions to Non-Receptor Proteins
Toth, A. D.; Soltesz-Katona, E.; Kis, K.; Guti, V.; Gilzer, S.; Prokop, S.; Boros, R.; Misak, A.; Balla, A.; Varnai, P.; Turiak, L.; Acs, A.; Drahos, L.; Inoue, A.; Hunyady, L.; Turu, G.
10.1101/2023.08.04.551955 — biochemistry — Posted on 2023-08-04
4002 Thymus formation in uncharted embryonic territories.
Alcobia, I.; Gama-Carvalho, M.; Magalhaes, L.; Proa, V.; Henrique, D.; Neves, H.
10.1101/2022.03.09.483697 — developmental biology — Posted on 2023-08-04
4004 Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
Ayoubi, R.; Ryan, J.; Biddle, M. S.; Alshafie, W.; Fotouhi, M.; Bolivar, S. G.; Moleon, V. R.; Eckmann, P.; Worrall, D.; McDowell, I.; Southern, K.; Reintsch, W.; Durcan, T. M.; Brown, C. M.; Bandrowski, A. E.; Virk, H. S.; Edwards, A. M.; McPherson, P. S.; Laflamme, C.
10.1101/2023.06.01.543292 — molecular biology — Posted on 2023-08-04
4005 Epiphenomenal neural activity in the primate cortex
Tremblay, S.; Testard, C.; Inchauspe, J.; Petrides, M.
10.1101/2022.09.12.506984 — neuroscience — Posted on 2023-08-04
4012 Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum
Li, J.; Sharma, M.; Meek, R. W.; Alhifthi, A.; Armstrong, Z.; Madiedo Soler, N.; Lee, M.; Goddard-Borger, E. D.; Blaza, J. N.; Davies, G. J.; Williams, S. J.
10.1101/2023.03.13.532361 — biochemistry — Posted on 2023-08-04
4013 A broad-spectrum α-glucosidase of glycoside hydrolase family 13 from Marinovum sp., a member of the Roseobacter clade
Li, J.; Mui, J. W.- Y.; da Silva, B. M.; Pires, D. E. V.; Ascher, D. B.; Madiedo Soler, N.; Goddard-Borger, E. D.; Williams, S. J.
10.1101/2023.03.31.535182 — biochemistry — Posted on 2023-08-04
4015 Genetic similarity between relatives provides evidence on the presence and history of assortative mating
Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.
10.1101/2023.06.27.546663 — genetics — Posted on 2023-08-04
4017 Nitric oxide feedback to ciliary photoreceptor cells gates a UV avoidance circuit
Jokura, K.; Ueda, N.; Guehmann, M.; Yanez-Guerra, L. A.; Slowinski, P.; Wedgwood, K. C.; Jekely, G.
10.1101/2023.08.02.551600 — neuroscience — Posted on 2023-08-04
4018 Spindle-locked ripples mediate memory reactivation during human NREM sleep.
Schreiner, T.; Griffiths, B. J.; Kutlu, M.; Vollmar, C.; Kaufmann, E.; Quach, S.; Remi, J.; Noachtar, S.; Staudigl, T.
10.1101/2023.01.27.525854 — neuroscience — Posted on 2023-08-04
4019 Analyzing postprandial metabolomics data using multiway models: A simulation study
Li, L.; Yan, S.; Bakker, B. M.; Hoefsloot, H.; Chawes, B.; Horner, D.; Rasmussen, M. A.; Smilde, A. K.; Acar, E.
10.1101/2022.12.19.521154 — systems biology — Posted on 2023-08-04
4020 The NPH3-domain protein NRL5 is a plant specific type of GTPase essential for drought resistance
UPADHYAY-TIWARI, N.; Huang, X.-J.; Lee, Y.-C.; Singh, S. K.; Hsu, C.-C.; Huang, S.-S.; Verslues, P. E.
10.1101/2023.05.10.540297 — plant biology — Posted on 2023-08-04
4021 The PALB2 DNA-binding domain is an intrinsically disordered recombinase
Kyriukha, Y.; Watkins, M. B.; Redington, J. M.; Dastvan, R.; Uversky, V. N.; Hopkins, J. B.; Pozzi, N.; Korolev, S.
10.1101/2023.06.01.543259 — biophysics — Posted on 2023-08-04
4023 A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression
Salvador-Garcia, D.; Jin, L.; Hensley, A.; Golcuk, M.; Gallaud, E.; Chaaban, S.; Port, F.; Vagnoni, A.; Planelles-Herrero, V. J.; McClintock, M. A.; Derivery, E.; Carter, A. P.; Giet, R.; Gur, M.; Yildiz, A.; Bullock, S. L.
10.1101/2023.08.03.551815 — cell biology — Posted on 2023-08-04
4024 Size dependent steady-state saturation limit in biomolecular transport through nuclear membranes
Padinhare kandiyil, S.; Meethale Mangalassery, B.; J, H.; Joseph, T.; Patincharath, N.; Varier, G. K.
10.1101/2023.08.02.551582 — biophysics — Posted on 2023-08-04
4025 Molecular Studies of Phages-Klebsiella pneumoniae in a Mucoid Environment: Innovative use of mucolytic agents prior to the administration of lytic phages
Pacios, O.; Blasco, L.; Ortiz-Cartagena, C.; Bleriot, I.; Fernandez-Garcia, L.; Lopez, M.; Barrio-Pujante, A.; Pascual, A.; Fernandez-Cuenca, F.; Martinez-Martinez, L.; Aracil, B.; Oteo-Iglesias, J.; Tomas, M.
10.1101/2023.08.02.551690 — microbiology — Posted on 2023-08-04
4026 GreenGate 2.0: backwards compatible addons for assembly of complex transcriptional units and their stacking with GreenGate
Piepers, M.; Erbstein, K.; Reyes-Hernandez, J.; Song, C.; Tessi, T.; Petrasiunaite, V.; Faerber, N.; Distel, K.; Maizel, A.
10.1101/2023.08.02.551719 — plant biology — Posted on 2023-08-04
4032 Principal and Independent Genomic Components of Brain Structure and Function
Oblong, L. M.; Soheili-Nezhad, S.; Trevisan, N.; Shi, Y.; Beckmann, C. F.; Sprooten, E.
10.1101/2022.07.13.499912 — neuroscience — Posted on 2023-08-04
4033 Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation
Isbister, J. B.; Ecker, A.; Pokorny, C.; Bolanos-Puchet, S.; Egas Santander, D.; Arnaudon, A.; Awile, O.; Barros-Zulaica, N.; Blanco Alonso, J.; Boci, E.; Chindemi, G.; Courcol, J.-D.; Damart, T.; Delemontex, T.; Dietz, A.; Ficarelli, G.; Gevaert, M.; Herttuainen, J.; Ivaska, G.; Ji, W.; Keller, D.; King, J.; Kumbhar, P.; Lapere, S.; Litvak, P.; Mandge, D.; Muller, E. B.; Pereira, F.; Planas, J.; Ranjan, R.; Reva, M.; Romani, A.; Rössert, C.; Schürmann, F.; Sood, V.; Teska, A.; Tuncel, A.; Van Geit, W.; Wolf, M.; Markram, H.; Ramaswamy, S.; Reimann, M. W.
10.1101/2023.05.17.541168 — neuroscience — Posted on 2023-08-04
4036 The evolution of borneol repellency in culicine mosquitoes
Vainer, Y.; Wang, Y.; Huff, R. M.; Ghaninia, M.; Coutinho-Abreu, I. V.; Sar-Shalom, E.; Ruiz, C.; Perets, D.; Yakir, E.; Rajamanickam, D.; Warburg, A.; Papathanos, P. A.; Akbari, O.; Ignell, R.; Riffell, J. A.; Pitts, J.; Bohbot, J. D.
10.1101/2023.08.01.548337 — evolutionary biology — Posted on 2023-08-04
4037 Spatio-temporal patterns of whiting (Merlangius merlangus) in the Adriatic Sea under environmental forcing
Asciutto, E.; Maioli, F.; Manfredi, C.; Anibaldi, A.; Cimini, J.; Isailovic, I.; Marceta, B.; Casini, M.
10.1101/2023.08.01.551447 — ecology — Posted on 2023-08-04
4038 Host lifestyle and parasite interspecific facilitation mediate co-infection in a species-poor host-parasite system
Kmentova, N.; Cruz-Laufer, A. J.; Milec, L.; Moons, T.; Heeren, S.; van den Hoorn, E.; Thys, K. J. M.; Makasa, L.; Chocha Manda, A.; Masilya Mulungula, P.; Van Steenberge, M.; Jorissen, M.; Vanhove, M. P. M.
10.1101/2023.01.03.522369 — ecology — Posted on 2023-08-04
4039 Spatio-temporal patterns of whiting (Merlangius merlangus) in the Adriatic Sea under environmental forcing
Asciutto, E.; Maioli, F.; Manfredi, C.; Anibaldi, A.; Cimini, J.; Isailovic, I.; Marceta, B.; Casini, M.
10.1101/2023.08.01.551447 — ecology — Posted on 2023-08-04
4051 Human Intelligence and the Connectome are Driven by Structural Brain Network Control
Anderson, E. D.; Varshney, L. R.; Hemmatian, B.; Robles-Granda, P. D.; Nayak, A. K.; Wilcox, R. R.; Zwilling, C. E.; Kim, B.; Barbey, A. K.
10.1101/2023.08.02.551642 — neuroscience — Posted on 2023-08-03
4054 Endocytosis gated by emergent properties of membrane-clathrin interactions
Wang, X.; Li, Y.; Liu, A.; Padilla, R.; Lee, D. M.; Kim, D.; Mettlen, M.; Chen, Z.; Schmid, S. L.; Danuser, G.
10.1101/2023.08.02.551737 — biophysics — Posted on 2023-08-03
4055 Time-deterministic cryo-optical microscopy
Yamanaka, M.; Tsuji, K.; Kumamoto, Y.; Tamura, S.; Miyamura, W.; Kubo, T.; Mizushima, K.; Kono, K.; Hirano, H.; Sugiura, K.; Fukushima, S.-i.; Kunimoto, T.; Nishida, K.; Mochizuki, K.; Harada, Y.; Smith, N. I.; Heintzmann, R.; Nagai, T.; Tanaka, H.; Fujita, K.
10.1101/2023.08.01.551103 — biophysics — Posted on 2023-08-03
4057 Assessment of tobacco and N. benthamiana as biofactories of irregular monoterpenes for sustainable crop protection.
Mateos-Fernandez, R.; Vacas, S.; Navarro-Fuertes, I.; Navarro-Llopis, V.; Orzaez, D.; Gianoglio, S.
10.1101/2023.08.02.551635 — molecular biology — Posted on 2023-08-03
4058 Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.
Estevam, G. O.; Linossi, E. M.; Macdonald, C. B.; Espinoza, C. A.; Michaud, J. M.; Coyote-Maestas, W.; Collisson, E. A.; Jura, N.; Fraser, J. S.
10.1101/2023.08.03.551866 — molecular biology — Posted on 2023-08-03
4059 Different low-complexity regions of SFPQ play distinct roles in the formation of biomolecular condensates
Marshall, A. C.; Cummins, J.; Kobelke, S.; Zhu, T.; Widagdo, J.; Anggono, V.; Hyman, A.; Fox, A. H.; Bond, C. S.; Lee, M.
10.1101/2022.11.30.518278 — molecular biology — Posted on 2023-08-03
4060 An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes
Caielli, S.; Balasubramanian, P.; Rodriguez-Alcazar, J.; Balaji, U.; Wan, Z.; Baisch, J.; Smitherman, C.; Walters, L.; Sparagana, P.; Nehar-Belaid, D.; Marches, R.; Nassi, L.; Stewart, K.; Fuller, J.; Banchereau, J. F.; Gu, J.; Wright, T.; Pascual, V.
10.1101/2023.08.03.551696 — immunology — Posted on 2023-08-03
4061 Unique T cell signatures are associated with reduced Chlamydia trachomatis reinfection in a highly exposed cohort
Yount, K. S.; Kollipara, A.; Liu, C.; Zheng, X.; O'Connell, C. M.; Bagwell, B.; Wiesenfeld, H. C.; Hillier, S. L.; Darville, T.
10.1101/2023.08.02.551709 — immunology — Posted on 2023-08-03
4066 Highly conserved, positively charged tandem repeats mediate multimerization of ice nucleation proteins
Hansen, T.; Lee, J. C.; Reicher, N.; Ovadia, G.; Guo, S.; Guo, W.; Liu, J.; Braslavsky, I.; Rudich, Y.; Davies, P. L.
10.1101/2023.08.03.551873 — biochemistry — Posted on 2023-08-03
4067 Hotspot propensity across mutational processes
Arnedo, C.; Muinos, F.; Gonzalez-Perez, A.; Lopez-Bigas, N.
10.1101/2022.09.14.507952 — genomics — Posted on 2023-08-03
4069 A protein hydroxylase couples epithelial membrane biology to nucleolar ribosome biogenesis
Hendrix, E.; Andrijes, R.; Boora, U.; Kaur, A.; Bundred, J. R.; Officer-Jones, L.; pennie, r.; Powley, I.; Zayer, A.; Heilig, R.; Westrip, C. A. E.; Fletcher, S. F.; Eaton, C. D.; Kennedy, T. J.; Piasecka, S.; Fischer, R.; Smerdon, S. J.; Le Quesne, J.; Coleman, M. L.
10.1101/2023.03.15.532818 — cell biology — Posted on 2023-08-03
4070 Revisiting chromatin packaging in mouse sperm
Yin, Q.; Yang, C.-H.; Strelkova, O.; Wu, J.; Sun, Y. H.; Gopalan, S.; Yang, L.; Dekker, J.; Fazzio, T. G.; Li, X. G.; Gibcus, J.; Rando, O.
10.1101/2022.12.26.521943 — molecular biology — Posted on 2023-08-03
4073 Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila
Steinbach, A. M.; Bhadkamkar, V. L.; Jimenez-Morales, D.; Stevenson, E.; Jang, G. M.; Krogan, N. J.; Swaney, D. L.; Mukherjee, S.
10.1101/2023.08.03.551750 — microbiology — Posted on 2023-08-03
4075 Teosinte Pollen Drive guides maize domestication and evolution by RNAi
Berube, B.; Ernst, E.; Cahn, J.; Roche, B.; de Santis Alves, C.; Lynn, J.; Scheben, A.; Siepel, A.; Ross-Ibarra, J.; Kermicle, J.; Martienssen, R. A.
10.1101/2023.07.12.548689 — plant biology — Posted on 2023-08-03
4080 Fucosylated glycoproteins and fucosylated glycolipids play opposing roles in cholera intoxication
Ghorashi, A. C.; Boucher, A.; Archer-hartmann, S. A.; Murray, N. B.; Konada, R. S. R.; Zhang, X.; Xing, C.; Azadi, P.; Yrlid, U.; Kohler, J. J.
10.1101/2023.08.02.551727 — biochemistry — Posted on 2023-08-03
4083 Enhancing grapevine breeding efficiency through genomic prediction and selection index
Brault, C.; Segura, V.; Roques, M.; Lamblin, P.; Bouckenooghe, V.; Pouzalgues, N.; Cunty, C.; Breil, M.; Frouin, M.; Garcin, L.; Camps, L.; Ducasse, M.-A.; Romieu, C.; Masson, G.; Juillard, S.; Flutre, T.; Le Cunff, L.
10.1101/2023.07.31.551371 — genetics — Posted on 2023-08-03
4084 Effects of ancient anthropogenic clam gardens on the growth, survival, and transcriptome of Pacific littleneck clams (Leukoma staminea)
Raap, M. R.; Gurney-Smith, H. J.; Dudas, S. E.; Pearce, C. M.; Leong, J. S.; Sutherland, B. J. G.; Koop, B. F.
10.1101/2022.09.09.507365 — ecology — Posted on 2023-08-03
4085 m6A mRNA Methylation Regulates Early Pancreatic β-Cell Differentiation
Kahraman, S.; De Jesus, D. F.; Wei, J.; Brown, N. K.; Zou, Z.; Hu, J.; He, C.; Kulkarni, R. N.
10.1101/2023.08.03.551675 — developmental biology — Posted on 2023-08-03
4086 Improved rescue of immature oocytes obtained from conventional gonadotropin stimulation cycles via human induced pluripotent stem cell-derived ovarian support cell co-culture
Giovannini, A.; Piechota, S.; Marchante, M.; Potts, K. S.; Rockwell, G.; Paulsen, B.; Noblett, A. D.; Figueroa, A. B.; Aschenberger, C.; Kelk, D. A.; Forti, M.; Marcinyshyn, S.; Barrachina, F.; Wiemer, K.; Sanchez, M.; Belchin, P.; Pierson Smela, M.; Fortuna, P. R.; Chatterjee, P.; McCulloh, D. H.; Ordonez-Perez, D.; Klein, J. U.; Kramme, C. C.
10.1101/2023.03.27.534477 — developmental biology — Posted on 2023-08-03
4087 ATAC and SAGA coactivator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
Yayli, G.; Bernardini, A.; Mendoza Sanchez, P. K.; Scheer, E.; Damilot, M.; Essabri, K.; Morlet, B.; Negroni, L.; Vincent, S. D.; Timmers, H. T. M.; Tora, L.
10.1101/2023.08.03.551787 — molecular biology — Posted on 2023-08-03
4088 Retrotransposon addiction promotes centromere function via epigenetically activated small RNAs
Shimada, A.; Cahn, J.; Ernst, E.; Lynn, J.; Grimanelli, D.; Henderson, I. R.; Kakutani, T.; Martienssen, R. A.
10.1101/2023.08.02.551486 — molecular biology — Posted on 2023-08-03
4089 Evaluation of Loop-Mediated Isothermal Amplification (LAMP) for Rapid Detection of Campylobacter jejuni
Caro-Castro, J.; Orellana-Peralta, F.; Flores-Leon, D.; Cucho-Meza, E.; Gavilan, R. G.; Quino Sifuentes, W.
10.1101/2023.08.03.551860 — molecular biology — Posted on 2023-08-03
4092 Trichinella spiralis secretes stage-specific extracellular vesicles for modulating host microenvironment for parasitism.
KhueangchiangKhwang, S.; Wu, Z.; Hosoda-Yabe, R.; Yabe, T.; Okamoto, T.; Takada, C.; Okada, H.; Ogura, S.; MAEKAWA, Y.
10.1101/2023.08.02.551739 — microbiology — Posted on 2023-08-03
4093 In vitro impact of fluconazole on oral microbial communities, bacterial growth and biofilm formation
Dornelas, L. M.; Ricomini Filho, A. P.; Junges, R.; Amdal, H. A.; Cury, A. D. B.; Petersen, F. C.
10.1101/2023.08.03.551749 — microbiology — Posted on 2023-08-03
4094 Metabolic reprogramming during Candida albicans planktonic-biofilm transition is modulated by the ZCF15 and ZCF26 paralogs
Rai, L. S.; Chauvel, M.; Sanchez, H.; van Wijlick, L.; Maufrais, C.; Cokelaer, T.; Sertour, N.; Legrand, M.; Andes, D. R.; Bachellier-Bassi, S.; d'Enfert, C.
10.1101/2023.08.03.551767 — microbiology — Posted on 2023-08-03
4096 DOCK2-deficiency causes defects in anti-viral T cell responses and poor control of herpes simplex virus infection
Randall, K. L.; Flesch, I. E. A.; Mei, Y.; Miosge, L. A.; Aye, R.; Aye, R.; Yu, Z.; Domaschenz, H.; Hollett, N.; Russell, T.; Stefanovic, T.; Wong, Y. C.; Goodnow, C. C.; Bertram, E.; Enders, A.; Tscharke, D.
10.1101/2023.08.02.551154 — immunology — Posted on 2023-08-03
4098 Excitation creates a distributed pattern of cortical suppression due to varied recurrent input
O'Rawe, J. F.; Zhou, Z.; Li, A. J.; LaFosse, P. K.; Goldbach, H. C.; Histed, M. H.
10.1101/2022.08.31.505844 — neuroscience — Posted on 2023-08-03
4099 Molecular tuning of sea anemone stinging
He, L. S.; Qi, Y.; Allard, C. A.; Valencia-Montoya, W. A.; Krueger, S. P.; Weir, K.; Seminara, A.; Bellono, N. W.
10.1101/2023.06.15.545144 — physiology — Posted on 2023-08-03
4104 Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme
Adak, S.; Ye, N.; Calderone, L. A.; Schafer, R. J. B.; Lukowski, A. L.; Pandelia, M.-E.; Drennan, C. L.; Moore, B. S.
10.1101/2023.08.03.551874 — biochemistry — Posted on 2023-08-03
4107 Human induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation
Piechota, S.; Marchante, M.; Giovannini, A.; Paulsen, B.; Potts, K. S.; Rockwell, G.; Aschenberger, C.; Noblett, A. D.; Figueroa, A. B.; Sanchez, M.; Barrachina, F.; Wiemer, K.; Guzman, L.; Belchin, P.; Pierson Smela, M.; Fortuna, P. R.; Chatterjee, P.; Tran, N. D.; Kelk, D. A.; Forti, M.; Marcinyshyn, S.; Smith, T.; McCulloh, D. H.; Ortiz, S.; Klein, J.; Klatsky, P.; Ordonez-Perez, D.; Kramme, C. C.
10.1101/2023.03.27.534479 — developmental biology — Posted on 2023-08-03
4108 The cortical microtubules of Toxoplasma gondii underlie the helicity of parasite movement
Tengganu, I. F.; Arias Padilla, L. F.; Munera Lopez, J.; Liu, J.; Brown, P. T.; Murray, J. M.; Hu, K.
10.1101/2023.04.23.538011 — cell biology — Posted on 2023-08-03
4111 Exposure to mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection
Mai, D.; Jahn, A.; Murray, T.; Morikubo, M.; Lim, P. N.; Cervantes, M. M.; Pham, L. K.; Nemeth, J. C.; Urdahl, K. B.; Diercks, A. H.; Aderem, A.; Rothchild, A. C.
10.1101/2022.09.19.507309 — immunology — Posted on 2023-08-03
4114 Direct observation of the neural computations underlying a single decision
Steinemann, N. A.; Stine, G. M.; Trautmann, E. M.; Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.
10.1101/2022.05.02.490321 — neuroscience — Posted on 2023-08-03
4115 Primacy of vision shapes behavioral strategies and neural substrates of spatial navigation in the hippocampus of the common marmoset
Piza, D. B.; Corrigan, B. W.; Gulli, R. A.; Do Carmo, S.; Cuello, A. C.; Muller, L.; Martinez-Trujillo, J. C.
10.1101/2023.05.24.542209 — neuroscience — Posted on 2023-08-03
4118 Predictors of Population Estimates in a Critically Endangered Species of Black-and-White Colobus Monkeys
Wikberg, E.; Glotfelty, E.; Yeboah Adu, B.; Koranteng, R.; Kodom, C.; Owusu Anfwi, B.; Boahen, A.
10.1101/2023.08.01.551493 — zoology — Posted on 2023-08-03
4120 Pathogenic mutations of human phosphorylation sites affect protein-protein interactions
Rrustemi, T.; Meyer, K.; Roske, Y.; Uyar, B.; Akalin, A.; Imami, K.; Ishihama, Y.; Daumke, O.; Selbach, M.
10.1101/2023.08.01.551433 — systems biology — Posted on 2023-08-03
4121 Metabolic slowdown as the proximal cause of ageing and death
Wordsworth, J.; Yde Nielsen, P.; Fielder, E.; Chandrasegaran, S.; Shanley, D.
10.1101/2023.08.01.551537 — systems biology — Posted on 2023-08-03
4123 A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks
Feng, S.; Sanford, J. A.; Weber, T. J.; Hutchinson-Bunch, C. M.; Dakup, P. P.; Paurus, V. L.; Attah, K.; Sauro, H. A.; Qian, W.-J.; Wiley, H. S.
10.1101/2023.08.03.551714 — systems biology — Posted on 2023-08-03
4124 Effect of percutaneous ventricular assisted device on post-cardiac arrest myocardial dysfunction in swine model with prolonged cardiac arrest
Nakashima, T.; Tiba, M. H.; Hsu, C. H.; Gottula, A. L.; McCracken, B. M.; Greer, N. L.; Cramer, T. A.; Sutton, N. R.; Ward, K. R.; Neumar, R. W.
10.1101/2023.08.01.551568 — physiology — Posted on 2023-08-03
4127 Systematic characterization of therapeutic vulnerabilities in Multiple Myeloma with Amp1q reveals increased sensitivity to the combination of MCL1 and PI3K inhibitors
Sklavenitis-Pistofidis, R.; Lightbody, E. D.; Reidy, M.; Tsuji, J.; Aranha, M. P.; Heilpern-Mallory, D.; Huynh, D.; Chong, S. J. F.; Hackett, L.; Haradhvala, N. J.; Wu, T.; Su, N. K.; Berrios, B.; Alberge, J.-B.; Dutta, A.; Davids, M. S.; Papaioannou, M.; Getz, G.; Ghobrial, I. M.; Manier, S.
10.1101/2023.08.01.551480 — cancer biology — Posted on 2023-08-03
4128 Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons
Lin, W.; Wall, J.; Li, G.; Newman, D.; VandeBerg, J.; Yang, Y.; Abney, M.; Olivier, M.; Gilad, Y.; Cox, L. A.
10.1101/2023.08.01.551489 — genomics — Posted on 2023-08-03
4130 Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts
Raskind, W.; Chapman, N.; Navas, P.; Dorschner, M.; Mehaffey, M.; Wigg, K.; Price, K.; Naumova, O.; Elizabeth, K.; Guger, S.; Lovett, M.; Grigorenko, E.; Berninger, V.; Barr, C.; Wijsman, E.
10.1101/2023.08.01.551585 — genetics — Posted on 2023-08-03
4132 REPRODUCTIVE COMPATIBILITY OF TWO LINES OF DELIA PLATURA (DIPTERA: ANTHOMYIIDAE)
Bush-Beaupre, A.; Belisle, M.; Fortier, A.-M.; Fournier, F.; MacDonald, A.; Savage, J.
10.1101/2023.08.01.551352 — ecology — Posted on 2023-08-03
4133 Antibody gene features associated with binding and functional activity in vaccine-derived human mAbs targeting malaria parasites
Coelho, C.; Marquez, S.; Tentokam, B. T.; Berhe, A.; Miura, k.; Long, C.; Healy, S.; Sagara, I.; Kleinstein, S.; Duffy, P.
10.1101/2023.08.01.551554 — immunology — Posted on 2023-08-03
4134 A unique human cord blood CD8+CD45RA+CD27+CD161+ T cell subset identified by flow cytometric data analysis using Seurat
Reyes, J. G. A.; Ni, D.; Santner-Nanan, B.; Pinget, G. V.; Kraftova, L.; Ashhurst, T. M.; Marsh-Wakefield, F.; Wishart, C.; Tan, J.; Hsu, P.; King, N. J. C.; Macia, L.; Nanan, R.
10.1101/2023.08.01.549954 — immunology — Posted on 2023-08-03
4135 CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma
Torres, G. M.; Jarnagin, H. C.; Park, C.; Yang, H.; Kosarek, N. N.; Bhandari, R.; Wang, C.-Y.; Kolling, F. W.; Whitfield, M. L.; Turk, M. J.; Liby, K. T.; Pioli, P. A.
10.1101/2023.08.01.551524 — immunology — Posted on 2023-08-03
4137 Meta-analytic decoding of the cortical gradient of functional connectivity
Peraza, J. A.; Salo, T.; Riedel, M. C.; Bottenhorn, K. L.; Poline, J.-B.; Dockes, J.; Kent, J. D.; Bartley, J. E.; Flannery, J. S.; Hill-Bowen, L. D.; Lobo, R. P.; Poudel, R.; Ray, K. L.; Robinson, J. L.; Laird, R. W.; Sutherland, M. T.; de la Vega, A.; Laird, A. R.
10.1101/2023.08.01.551505 — neuroscience — Posted on 2023-08-03
4138 Specific configurations of electrical synapses filter sensory information to drive choices in behavior
Almoril-Porras, A.; Calvo, A.; Niu, L.-G.; Beagan, J.; Hawk, J. D.; Aljobeh, A.; Wisdom, E.; Ren, I.; Diaz-Garcia, M.; Wang, Z.-W.; Colon-Ramos, D.
10.1101/2023.08.01.551556 — neuroscience — Posted on 2023-08-03
4140 Autoimmune inflammation triggers aberrant astrocytic calcium signaling to impair synaptic plasticity
Baraibar, A. M.; Colomer, T.; Moreno-Garcia, A.; Bernal-Chico, A.; Sanchez, E.; Utrilla, C.; Serrat, R.; Soria-Gomez, E.; Rodriguez-Antiguedad, A.; Araque, A.; Matute, C.; Marsicano, G.; Mato, S.
10.1101/2023.08.01.551248 — neuroscience — Posted on 2023-08-03
4141 Data-driven signal analysis of sensory cortical processing using high-resolution fMRI across different studies
Plagwitz, L.; Choi, S.; Yu, X.; Segelcke, D.; Pogatzki-Zahn, E. M.; Varghese, J.; Faber, C.; Pradier, B.
10.1101/2023.08.01.551587 — neuroscience — Posted on 2023-08-03
4142 Heterologous expression of influenza hemagglutinin leads to early and transient activation of the unfolded protein response in Nicotiana benthamiana
Hamel, L.-P.; Comeau, M.-A.; Tardif, R.; Poirier-Gravel, F.; Pare, M.-E.; Lavoie, P.-O.; Goulet, M.-C.; Michaud, D.; D Aoust, M.-A.
10.1101/2023.08.03.550084 — plant biology — Posted on 2023-08-03
4143 Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases
Evoli, S.; Kariyawasam, N. L.; Nitiss, K. C.; Nitiss, J. L.; Wereszczynski, J.
10.1101/2023.08.02.551689 — biophysics — Posted on 2023-08-03
4144 Dissecting Mechanisms of Ligand Binding and Conformational Changes in the Glutamine-Binding Protein
Han, Z.; Panhans, S.; Brameyer, S.; Bilgen, E.; Ram, M.; Herr, A.; Narducci, A.; Isselstein, M.; Harris, P.; Brix, O.; Jung, K.; Lamb, D. C.; Lerner, E.; Griffith, D.; Weikl, T.; Zijlstra, N.; Cordes, T.
10.1101/2023.08.02.551720 — biophysics — Posted on 2023-08-03
4145 Time-deterministic cryo-optical microscopy
Yamanaka, M.; Tsuji, K.; Kumamoto, Y.; Tamura, S.; Miyamura, W.; Kubo, T.; Mizushima, K.; Kono, K.; Hirano, H.; Sugiura, K.; Fukushima, S.-i.; Kunimoto, T.; Nishida, K.; Mochizuki, K.; Harada, Y.; Smith, N. I.; Heintzmann, R.; Nagai, T.; Tanaka, H.; Fujita, K.
10.1101/2023.08.01.551103 — biophysics — Posted on 2023-08-03
4151 Evolutionary genomics identifies host-directed therapeutics to treat intracellular bacterial infections
Medicielo, J.; Waltari, E.; Glascock, A. L.; Dudas, G.; DeFelice, B.; Gray, I.; Tato, C. M.; Wong, J.; Ahyong, V.
10.1101/2023.08.01.551011 — genomics — Posted on 2023-08-03
4152 PharaohFUN: PHylogenomic Analysis foR plAnt prOtein History and FUNction elucidation
Ramos-Gonzalez, M.; Ramos-Gonzalez, V.; Arvanitidou, C.; Hernandez-Garcia, J.; Garcia-Gonzalez, M.; Romero-Campero, F. J.
10.1101/2023.08.01.551440 — evolutionary biology — Posted on 2023-08-03
4153 Meta-analysis of herbicide non-target effects on pest natural enemies
Zilnik, G.; Bergeron, P. E.; Chuang, A.; Diepenbrock, L.; Hanel, A.; Middleton, E.; Moretti, E.; Schmidt-Jeffris, R.
10.1101/2023.08.01.551535 — ecology — Posted on 2023-08-03
4154 Phenological mismatch between trees and wildflowers: Reconciling divergent findings in two recent analyses
Lee, B. R.; Alecrim, E. F.; Forrest, J. R. K.; Heberling, J. M.; Primack, R. B.; Sargent, R. D.
10.1101/2023.08.01.551551 — ecology — Posted on 2023-08-03
4155 Plant-mediated effects of fire and fragmentation drive plant-pollinator interaction β-diversity in fire-dependent pine savannas
Moreno-Garcia, P.; Freeman, J. E.; Campbell, J. W.; Broadbent, E. N.; Almeyda Zambrano, A. M.; Prata, G.; de Almeida, D. R. A.; Gilb, S.; Baiser, B.
10.1101/2023.08.01.551484 — ecology — Posted on 2023-08-03
4156 Isolation and genomic characterization of the tick-borne relapsing fever spirochete, Borrelia turicatae, from ticks collected in a peridomestic setting of Camayeca, Mexico
Vasquez-Guerrero, E.; Kneubehl, A. R.; Pellegrini-Hernandez, P.; Gonzales-Quiroz, J. L.; Dominguez-Lopez, M. L.; Krishnavajhala, A.; Estrada-de los Santos, P.; Ibarra, J. A.; Lopez, J. E.
10.1101/2023.08.01.551332 — ecology — Posted on 2023-08-03
4157 Identification of Core Yeast Species and Microbe-Microbe Interactions Impacting Larval Growth of Drosophila in the Wild
Mure, A.; Sugiura, Y.; Maeda, R.; Honda, K.; Sakurai, N.; Takahashi, Y.; Watada, M.; Katoh, T.; Gotoh, A.; Gotoh, Y.; Taniguchi, I.; Nakamura, K.; Hayashi, T.; Katayama, T.; Uemura, T.; Hattori, Y.
10.1101/2023.08.01.551563 — developmental biology — Posted on 2023-08-03
4158 SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation
Xu, H.; Dugue, G.; Cantaut-Belarif, Y.; Lejeune, F.-X.; Gupta, S.; Wyart, C.; Lehtinen, M. K.
10.1101/2023.08.01.551512 — neuroscience — Posted on 2023-08-03
4159 Monorhinal and Birhinal Odor Processing in Humans: an fMRI investigation
Ekanayake, A.; Yang, Q.; Kanekar, S.; Ahmed, B.; McCaslin, S.; Kalra, D.; Eslinger, P.; Karunanayaka, P.
10.1101/2023.08.01.551475 — neuroscience — Posted on 2023-08-03
4160 Combining video telemetry and wearable MEG for naturalistic imaging
O'Neill, G. C.; Seymour, R. A.; Mellor, S.; Alexander, N.; Tierney, T. M.; Bernachot, L.; Fahimi Hnazee, M.; Spedden, M. E.; Timms, R. C.; Bestmann, S.; Brookes, M. J.; Barnes, G. R.
10.1101/2023.08.01.551482 — neuroscience — Posted on 2023-08-03
4164 Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies
Joisa, C. U.; Chen, K. A.; Berginski, M.; Beville, S.; Stuhlmiller, T.; Okumu, D.; Golitz, B. T.; Johnson, G. L.; Gomez, S. M.
10.1101/2023.08.01.551346 — systems biology — Posted on 2023-08-03
4166 Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3
Hall, J.; Zhang, Z.; Wang, D.; Bhattacharya, S.; Alcantara, M.; Liang, Y.; Swiderski, P.; Forman, S.; Kwak, L.; Vaidehi, N.; Kortylewski, M.
10.1101/2023.08.01.551552 — cancer biology — Posted on 2023-08-03
4167 XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells
Zou, T.; Zhou, M.; Gupta, A.; Zhuang, P.; Fishbein, A. R.; Wei, H. Y.; Zhang, Z.; Cherniack, A. D.; Meyerson, M.
10.1101/2023.08.01.551488 — cancer biology — Posted on 2023-08-03
4175 Conductive microgel annealed scaffolds enhance myogenic potential of myoblastic cells
Casella, A.; Lowen, J.; Shimamoto, N.; Griffin, K. H.; Filler, A. C.; Panitch, A.; Leach, K.
10.1101/2023.08.01.551533 — bioengineering — Posted on 2023-08-03
4176 Fast clustering and cell-type annotation of scATAC data using pre-trained embeddings
LeRoy, N. J.; Smith, J. P.; Zheng, G.; Rymuza, J.; Gharavi, E.; Brown, D. E.; Zhang, A.; Sheffield, N. C.
10.1101/2023.08.01.551452 — genomics — Posted on 2023-08-03
4177 Island demographics and trait associations in white-tailed deer
Cars, B. S.; Kessler, C.; Hoffman, E. A.; Cote, S. D.; Koelsch, D.; Shafer, A. B.
10.1101/2023.08.01.551454 — genomics — Posted on 2023-08-03
4178 Mis-splicing Drives Loss of Function of p53E224D Point Mutation
Lock, I. C.; Leisenring, N. H.; Floyd, W.; Xu, E. S.; Luo, L.; Ma, Y.; Mansell, E. C.; Cardona, D. M.; Lee, C.-L.; Kirsch, D. G.
10.1101/2023.08.01.551439 — genomics — Posted on 2023-08-03
4179 Genetic differentiation at extreme latitudes in the socially plastic sweat bee Halictus rubicundus
Michels, B.; Beekman, M. M.; Field, J.; Gruber, J.; Pannebakker, B. A.; Savil, C.; Boulton, R. A.
10.1101/2023.08.01.551501 — genetics — Posted on 2023-08-03
4181 The genome of Litomosoides sigmodontis illuminates the origins of Y chromosomes in filarial nematodes
Stevens, L.; Kieninger, M.; Chan, B.; Wood, J. M. D.; Gonzalez de la Rosa, P.; Allen, J.; Blaxter, M.
10.1101/2023.08.02.550553 — evolutionary biology — Posted on 2023-08-03
4182 Spatio-temporal patterns of whiting (Merlangius merlangus) in the Adriatic Sea under environmental forcing
Asciutto, E.; Maioli, F.; Manfredi, C.; Anibaldi, A.; Cimini, J.; Isailovic, I.; Marceta, B.; Casini, M.
10.1101/2023.08.01.551447 — ecology — Posted on 2023-08-03
4185 Transposable element expression with variation in gonosome number supports a toxic Y effect on human longevity
Teoli, J.; Fablet, M.; Bardel, C.; Necsulea, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — molecular biology — Posted on 2023-08-03
4190 Smart Slides for Optical Monitoring of Cellular Processes
Ackermann, J.; Reger, E.; Jung, S.; Mohr, J.; Herbertz, S.; Seidl, K.; Kruss, S.
10.1101/2023.08.03.549853 — biochemistry — Posted on 2023-08-03
4192 The evolution of borneol repellency in culicine mosquitoes
Vainer, Y.; Wang, Y.; Huff, R. M.; Ghaninia, M.; Coutinho-Abreu, I.; Sar-Shalom, E.; Perets, D.; Yakir, E.; Rajamanickam, D.; Warburg, A.; Papathanos, P. A.; Ignell, R.; Riffell, J. A.; Pitts, J.; Bohbot, J. D.
10.1101/2023.08.01.548337 — evolutionary biology — Posted on 2023-08-03
4194 Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae
Ramos Sevillano, E.; Ercoli, G.; Betts, M.; Guerra-Assuncao, J. A.; Partridge, F.; Silva Entrudo Fernandes, V.; Wall, E.; Gordon, S.; Ferreira, D. S.; Heyderman, R.; Brown, J. S.
10.1101/2023.08.03.550501 — microbiology — Posted on 2023-08-03
4198 Adaptation of the Spalax galili transcriptome to life under hypoxia may hold a key to a complex phenotype including longevity and cancer resistance
Poetzsch, G.; Jelacic, L.; Bicker, A.; Balling, M.; Hellmann, L.; Dammer, L.; Andrade, M.; Shams, I.; Avivi, A.; Hankeln, T.
10.1101/2023.08.01.551427 — evolutionary biology — Posted on 2023-08-03
4200 Tremors in Time: Mechanically Induced Motor Tremors Influence
Gladhill, K.; De Kock, R.; Zhou, W.; Joiner, W. M.; Wiener, M.
10.1101/2023.08.01.551412 — neuroscience — Posted on 2023-08-03
4201 C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types
Broce, I.; Sirkis, D.; Nillo, R. M.; Bonham, L. W.; Lee, S. E.; Miller, B. L.; Sturm, V.; Sugrue, L. S.; Desikan, R.; Yokoyama, J. S.
10.1101/2023.07.17.549377 — neuroscience — Posted on 2023-08-03
4206 A versatile framework for drug-target interaction prediction by considering domain specific features
Liu, S.; Yu, J.; Ni, N.; Wang, Z.; Chen, M.; Li, Y.; Xu, C.; Bai, Q.; Ding, Y.; Wang, C.; Zhang, J.; Yao, X.; Liu, H.
10.1101/2023.08.01.551396 — bioinformatics — Posted on 2023-08-03
4208 Probing efficient microbial CO2 utilizationthrough metabolic and process modeling
Gorter de Vries, P. J.; Mol, V.; Sonnenschein, N. J.; Jensen, T. O.; Nielsen, A. T.
10.1101/2023.08.01.547650 — bioengineering — Posted on 2023-08-03
4209 An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Aguirre, T.; Dornan, G. L.; Hostachy, S.; Neuenschwander, M.; Seyffarth, C.; Haucke, V.; Schuetz, A.; von Kries, J. P.; Fiedler, D.
10.1101/2023.04.26.538378 — biochemistry — Posted on 2023-08-03
4210 Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius erato
Pinheiro de Castro, E. C.; McPherson, J.; Julian, G.; Mattila, A.; Bak, S.; Montgomery, S.; Jiggins, C.
10.1101/2023.01.13.523799 — evolutionary biology — Posted on 2023-08-03
4216 Regulation of the trade-off between cold stress and growth by BcGSTF10
Shen, Y. l.; Wang, G. p.; Ran, J. j.; Li, Y. r.; Wang, H. y.; Qiang, D.; Li, Y.; Hou, X. l.
10.1101/2023.08.03.551777 — plant biology — Posted on 2023-08-03
4217 Cryo-EM structure and functional landscape of an RNA polymerase ribozyme
McRae, E. K. S.; Wan, C. J. K.; Kristoffersen, E. L.; Hansen, K.; Gianni, E.; Gallego, I.; Curran, J. F.; Attwater, J.; Holliger, P.; Andersen, E. S.
10.1101/2022.08.23.504927 — biochemistry — Posted on 2023-08-03
4218 Pseudouridine guides germline small RNA transport and epigenetic inheritance
Herridge, R. P.; Dolata, J.; Migliori, V.; de Santis Alves, C.; Borges, F.; Van Ex, F.; Lin, A.; Bajczyk, M.; Leonardi, T.; Hendrick, A.; Schorn, A. J.; Kouzarides, T.; Martienssen, R. A.
10.1101/2023.05.27.542553 — genetics — Posted on 2023-08-03
4219 Harnessing Nature's nanoSecrets: biocompatibility, biodistribution and bioactivity of extracellular vesicles derived from microalgae
Adamo, G.; Santonicola, P.; Picciotto, S.; Gargano, P.; Nicosia, A.; Longo, V.; Aloi, N.; Romancino, D. P.; Paterna, A.; Rao, E.; Raccosta, S.; Noto, R.; Salamone, M.; Deidda, I.; Costa, S.; Di Sano, C.; Zampi, G.; Morsbach, S.; Landfester, K.; Colombo, P.; Wei, M.; Bergese, P.; Touzet, N.; Manno, M.; Di Schiavi, E.; Bongiovanni, A.
10.1101/2023.04.04.535547 — cell biology — Posted on 2023-08-03
4221 Cell-specialized chloroplast signaling orchestrates photosynthetic and extracellular reactive oxygen species for stress responses
Tee, E. E.; Fairweather, S. J.; Vo, H. M.; Zhao, C.; Breakspear, A.; Kimura, S.; Carmody, M.; Wrzaczek, M.; Broer, S.; Faulkner, C.; Kangasjarvi, J.; Chen, Z.-H.; Pogson, B. J.; Chan, K. X.
10.1101/2023.08.02.551742 — plant biology — Posted on 2023-08-03
4222 Immune cells employ intermittent integrin-mediated traction forces for 3D migration
Czerwinski, T.; Bischof, L.; Böhringer, D.; Kara, S.; Wittmann, E.; Winterl, A.; Gerum, R.; Nusser, G.; Wiesinger, M.; Budday, S.; Lux, A.; Voskens, C.; Fabry, B.; Mark, C.
10.1101/2023.04.20.537658 — biophysics — Posted on 2023-08-03
4224 Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery
Hanssen, F.; Garcia, M. U.; Folkersen, L.; Pedersen, A. S.; Lescai, F.; Jodoin, S.; Miller, E.; Wacker, O.; Smith, N.; nf-core community, ; Gabernet, G.; Nahnsen, S.
10.1101/2023.07.19.549462 — bioinformatics — Posted on 2023-08-03
4228 Polyadenylation of mRNAs encoding secreted proteins by TENT5 family of enzymes is essential for gametogenesis in mice.
Brouze, M.; Cieciura, A. C.; Gewartowska, O.; Kusio-Kobialka, M.; Jachacy, K.; Szpila, M.; Tarkowski, B.; Gruchota, J.; Krawczyk, P.; Mroczek, S.; Borsuk, E.; Dziembowski, A.
10.1101/2023.08.01.551432 — developmental biology — Posted on 2023-08-03
4233 Experience-dependent information routing through the basolateral amygdala
Antonoudiou, P.; Stone, B.; Colmers, P.; Evans-Strong, A.; Walton, N.; Weiss, G.; Maguire, J.
10.1101/2023.08.02.551710 — neuroscience — Posted on 2023-08-03
4235 Stimulation of mRNA translation rescues hippocampal synaptic plasticity and memory in mouse models of Alzheimer's disease
Ribeiro, F. C.; Cozachenco, D.; Argyrousi, E. K.; Staniszewski, A.; Wiebe, S.; Calixtro, J. D.; Soares-Neto, R.; Al-Chami, A.; El Sayegh, F.; Bermudez, S.; Arsenault, E.; Cossenza, M.; Lacaille, J.-C.; Nader, K.; Sun, H.; De Felice, F. G.; Lourenco, M. V.; Arancio, O.; Aguilar-Valles, A.; Sonenberg, N.; Ferreira, S. T.
10.1101/2023.08.03.551808 — neuroscience — Posted on 2023-08-03
4236 NAC1 directs CEP1-CEP3 peptidase expression and modulates root hair growth in Arabidopsis
Rodriguez-Garcia, D. R.; Rondon Guerrero, Y. d. C.; Ferrero, L. V.; Rossi, A. H.; Miglietta, E. A.; Aptekmann, A. A.; Marzol, E.; Martinez Pacheco, J.; Carignani, M.; Berdion Gabarain, V.; Lopez, L. E.; Diaz Dominguez, G.; Sanchez-Serrano, J. J.; Borassi, C.; Xu, L.; Nadra, A. D.; Rojo, E.; Ariel, F. D.; Estevez, J.
10.1101/2023.03.15.532802 — plant biology — Posted on 2023-08-03
4238 Enhancing grapevine breeding efficiency through genomic prediction and selection index
Brault, C.; Segura, V.; Roques, M.; Lamblin, P.; Bouckenooghe, V.; Pouzalgues, N.; Cunty, C.; Breil, M.; Frouin, M.; Garcin, L.; Camps, L.; Ducasse, M.-A.; Romieu, C.; Masson, G.; Juillard, S.; Flutre, T.; Le Cunff, L.
10.1101/2023.07.31.551371 — genetics — Posted on 2023-08-03
4239 Quantifying microbial guilds
Rivas-Santisteban, J.; Yubero, P.; Robaina-Estevez, S.; Gonzalez, J. M.; Tamames, J.; Pedros-Alio, C.
10.1101/2023.07.23.550202 — ecology — Posted on 2023-08-03
4240 Combined effects of climate warming and pharmaceuticals on a tri-trophic freshwater food web
Duchet, C.; Grabicova, K.; Kolar, V.; Lepsova, O.; Svecova, H.; Csercsa, A.; Zdvihalova, B.; Randak, T.; Boukal, D.
10.1101/2023.03.31.535078 — ecology — Posted on 2023-08-03
4241 Vertical transmission of maternal DNA through extracellular vesicles modulates embryo bioenergetics during the periconceptional period
Bolumar, D.; Moncayo-Arlandi, J.; Gonzalez-Fernandez, J.; Ochando, A.; Moreno, I.; Monteagudo-Sanchez, A.; Marin, C.; Diez, A.; Fabra, P.; Checa, M. A.; Espinos, J. J.; Gardner, D. K.; Simon, C.; Vilella, F.
10.1101/2023.04.21.537765 — developmental biology — Posted on 2023-08-03
4242 Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension
Fernandez-Gonzalez, A.; Mukhia, A.; Nadkarni, J.; Willis, G.; Reis, M.; Zhumka, K.; Vitali, S.; Liu, X.; Galls, A.; Mitsialis, S. A.; Kourembanas, S.
10.1101/2023.07.31.551394 — cell biology — Posted on 2023-08-03
4243 Tetherin restricts SARS-CoV-2 replication despite antagonistic effects of Spike and ORF7a
Hagelauer, E.; Lotke, R.; Kmiec, D.; Hu, D.; Hohner, M.; Stopper, S.; Layer, M.; Nchioua, R.; Kirchhoff, F.; Sauter, D.; Schindler, M.
10.1101/2023.07.28.550997 — microbiology — Posted on 2023-08-03
4244 Phages prevent biofilm formation on catheters under flow
Bseikri, H.; Michniewski, S.; Serrano, E. G.; Jameson, E.
10.1101/2023.07.26.550655 — microbiology — Posted on 2023-08-03
4247 Elucidating the activation mechanism for GBP1 oligomerization
Daumke, O.; Weismehl, M.; Chu, X.; Kutsch, M.; Lauterjung, P.; Herrmann, C.; Kudryashev, M.
10.1101/2023.08.01.551421 — biochemistry — Posted on 2023-08-03
4248 The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming
Barrero, M.; Lopez-Rubio, A. V.; Lazarenkov, A.; Blanco, E.; Bauer, M.; Palma, L. G.; Bigas, A.; Di Croce, L.; Sardina, J. L.; Payer, B.
10.1101/2023.07.31.551297 — genetics — Posted on 2023-08-03
4256 Antagonism of kappa opioid receptors worsens the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion
Flores, A. J.; Bartlett, M. J.; Seaton, B. T.; Samtani, G.; Sexauer, M. R.; Weintraub, N. C.; Siegenthaler, J. R.; Lu, D.; Heien, M. L.; Porreca, F.; Sherman, S. J.; Falk, T.
10.1101/2023.07.31.551112 — neuroscience — Posted on 2023-08-03
4258 Batch Effects are Causal Effects: Applications in Human Connectomics
Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2023-08-02
4264 Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γsecretase impairing downstream cell signaling
Zoltowska, K. M.; Utpal, D.; Lismont, S.; Enzlein, T.; Maesako, M.; Houser, M. C.; Gomes Moreira, D.; Franco, M. L.; Karachentsev, D.; Becker, A.; Hopf, C.; Vilar, M.; Berezovska, O.; Mobley, W.; Chavez-Gutierrez, L.
10.1101/2023.08.02.551596 — biochemistry — Posted on 2023-08-02
4266 Characterization of N-glycosylation and its Functional Role in SIDT1-Mediated RNA Uptake
Yang, T.; Xiao, H.; Chen, X.; Zheng, L.; Guo, H.; Wang, J.; Jiang, X.; Zhang, C.-Y.; Yang, F.; Ji, X.
10.1101/2023.08.01.551569 — biochemistry — Posted on 2023-08-02
4271 Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope
Wallace, M.; Zahr, H.; Perati, S.; Morsink, C. D.; Johnson, L. E.; Gacita, A. M.; Lai, S.; Wallrath, L. L.; Benjamin, I. J.; McNally, E.; Kirby, T. J.; Lammerding, J.
10.1101/2021.10.30.466591 — cell biology — Posted on 2023-08-02
4272 Mosquito midgut stem cell cellular defense response limits Plasmodium parasite infection
Ferreira Barletta, A. B.; Smith, J.; Burkart, E.; Bondarenko, S.; Sharakhov, I. V.; Criscione, F.; O'Brochta, D.; Barillas-Mury, C.
10.1101/2023.08.02.551669 — immunology — Posted on 2023-08-02
4275 Chromatin structure from high resolution microscopy: scaling laws and microphase separation
Remini, L.; Segers, M.; Palmeri, J.; Walter, J.-C.; Parmeggiani, A.; Carlon, E.
10.1101/2023.08.01.551471 — biophysics — Posted on 2023-08-02
4276 Mesoscale DNA Features Impact APOBEC3A and APOBEC3B Deaminase Activity and Shape Tumor Mutational Landscapes
Sanchez, A.; Ortega, P.; Sakhtemani, R.; Manjunath, L.; Oh, S.; Bournique, E.; Becker, A.; Kim, K.; Durfee, C.; Temiz, N. A.; Chen, X.; Harris, R.; Lawrence, M.; Buisson, R.
10.1101/2023.08.02.551499 — biochemistry — Posted on 2023-08-02
4277 Strategic engineering unlocks in vitro type II polyketide biosynthesis
Li, K. K.; Cho, Y. I.; Tran, M. A.; Wiedemann, C.; Koweek, R. S.; Hoang, N. K.; Hamrick, G.; Bowen, M.; Kokona, B.; Beld, J.; Hellmich, U.; Charkoudian, L. K.
10.1101/2023.08.02.551649 — biochemistry — Posted on 2023-08-02
4278 Anopheles gambiae mosGILT regulates innate immune genes and zpg expression
Arora, G.; Tang, X.; Cui, Y.; Yang, J.; Chuang, Y.-M.; Joshi, J.; Sajid, A.; Dong, Y.; Cresswell, P.; Dimopoulos, G.; Fikrig, E.
10.1101/2023.08.01.551536 — genomics — Posted on 2023-08-02
4279 High-throughput and genome-scale targeted mutagenesis using CRISPR in a non-model multicellular organism, Bombyx mori
Ma, S.; Zhang, T.; Wang, R.; Wang, P.; Liu, Y.; Chang, J.; Wang, A.; Lan, X.; Sun, L.; Sun, H.; Shi, R.; Lu, W.; Liu, D.; Zhang, N.; Hu, W.; Wang, X.; Xing, W.; Jia, L.; Xia, Q.
10.1101/2023.08.02.551621 — genomics — Posted on 2023-08-02
4281 Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory multi-omics study to identify composite biomarkers
Clarke, E. J.; Varela, L.; Jenkins, R. E.; Lozano-Andres, E.; Cywinska, A.; Przewozny, M.; van Weeren, R.; Lest, C. H. A. V. d.; Peffers, M. J.; Wauben, M.
10.1101/2023.08.02.551609 — molecular biology — Posted on 2023-08-02
4282 A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury
Boikova, A.; Quaife-Ryan, G. A.; Batho, C. A.; Lawrence, E.; Robinson, H.; Ascanelli, C.; Jennbacken, K.; Wang, Q.-D.; Hansson, K. M.; Seaton, A.; Rodriguez Noci, V.; Bywater, M.; Straube, J.; Sokolowski, K. A.; Tse, B. W.; Krieg, T.; Vujic, A.; Porrello, E. R.; Sinha, S.; Hudson, J. E.; Wilson, C. H.
10.1101/2023.08.02.551469 — molecular biology — Posted on 2023-08-02
4283 Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response
Ruperti, F.; Becher, I.; Stokkermans, A.; Wang, L.; Marschlich, N.; Potel, C.; Maus, E.; Stein, F.; Drotleff, B.; Schippers, K. J.; Nickel, M.; Prevedel, R.; Musser, J. M.; Savitski, M. M.; Arendt, D.
10.1101/2023.08.02.551666 — molecular biology — Posted on 2023-08-02
4284 Methanotrophic Methanoperedens archaea host diverse and interacting extrachromosomal elements
Shi, L.-D.; West-Roberts, J.; Schoelmerich, M. C.; Penev, P. I.; Chen, L.; Amano, Y.; Lei, S.; Sachdeva, R.; Banfield, J. F.
10.1101/2023.08.02.551345 — microbiology — Posted on 2023-08-02
4285 Molecular Basis of Cell Membrane Adaptation in Daptomycin-Resistant Enterococcus faecalis
Nguyen, A.; Tran, T.; Panesso, D.; Hood, K.; Polamraju, V.; Zhang, R.; Khan, A.; Miller, W. R.; Mileykovskaya, E.; Shamoo, Y.; Xu, L.; Vitrac, H.; Arias, C. A.
10.1101/2023.08.02.551704 — microbiology — Posted on 2023-08-02
4288 An In Vitro Medium for Modeling Gut Dysbiosis Associated with Cystic Fibrosis
Barrack, K.; Hampton, T. H.; Valls, R.; Surve, S.; Gardner, T.; Sanville, J.; Madan, J.; O'Toole, G.
10.1101/2023.08.01.551570 — microbiology — Posted on 2023-08-02
4289 A patchwork pathway for catabolism of the sulfosugar sulfofucose
Li, J.; Lee, M.; Yang, S.; Lewis, J. M.; Herisse, M.; Pidot, S. J.; Scott, N. E.; Williams, S. J.
10.1101/2023.08.01.551581 — microbiology — Posted on 2023-08-02
4290 Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance
Lu, B.; Wang, Y.; Wurihan, W.; Cheng, A.; Yeung, S.; Fondell, J. D.; Lai, Z.; Wan, D.; wu, x.; Li, V. W.; Fan, H.
10.1101/2023.08.02.551707 — microbiology — Posted on 2023-08-02
4291 Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis
Kaderabkova, N.; Furniss, R. C. D.; Maslova, E.; Eisaiankhongi, L.; Bernal, P.; Filloux, A.; Landeta, C.; Gonzalez, D.; McCarthy, R. R.; Mavridou, D.
10.1101/2023.08.02.551661 — microbiology — Posted on 2023-08-02
4292 The Human Microglia Atlas (HuMicA) Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative Conditions
Martins-Ferreira, R.; Calafell-Segura, J.; Leal, B.; Rodriguez-Ubreva, J.; Mereu, E.; Pinho e Costa, P.; Ballestar, E.
10.1101/2023.08.01.550767 — neuroscience — Posted on 2023-08-02
4299 Analytical code sharing practices in biomedical research
Sharma, N. K.; Ayyala, R.; Deshpande, D.; Patel, Y. M.; Munteanu, V.; Ciorba, D.; Fiscutean, A.; Vahed, M.; Sarkar, A.; Guo, R.; Moore, A.; Darci-Maher, N.; Nogoy, N. A.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2023.07.31.551384 — scientific communication and education — Posted on 2023-08-02
4300 Activation of the TRIF pathway and downstream targets results in the development of precancerous lesions during infection with Helicobacter.
Bali, P.; Lozano-Pope, I.; Hernandez, J.; Estrada, M. V.; Corr, M.; Turner, M. A.; Bouvet, M.; Benner, C.; Obonyo, M.
10.1101/2023.06.04.543598 — cancer biology — Posted on 2023-08-02
4302 The Interferon gamma Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming
Barrero, M.; Lopez-Rubio, A. V.; Lazarenkov, A.; Blanco, E.; Bauer, M.; Palma, L. G.; Bigas, A.; Di Croce, L.; Sardina, J. L.; Payer, B.
10.1101/2023.07.31.551297 — genetics — Posted on 2023-08-02
4305 Chromatin remodeling of histone H3 variants underlies epigenetic inheritance of DNA methylation
Lee, S. C.; Adams, D. W.; Ipsaro, J. J.; Cahn, J.; Lynn, J.; Kim, H.-S.; Berube, B.; Major, V.; Calarco, J. P.; LeBlanc, C.; Bhattacharjee, S.; Ramu, U.; Grimanelli, D.; Jacob, Y.; Voigt, P.; Joshua-Tor, L.; Martienssen, R. A.
10.1101/2023.07.11.548598 — molecular biology — Posted on 2023-08-02
4307 The inter-continental population dynamics of Neisseria gonorrhoeae
Osnes, M. N.; Brynildsrud, O. B.; Alfsnes, K.; van Dorp, L.; McKeand, S. A.; Ross, J.; Town, K.; De Korne-Elenbaas, J.; van Dam, A.; Bruisten, S.; de Blasio, B. F.; Caugant, D. A.; Grad, Y. H.; Williamson, D. A.; Balloux, F.; Didelot, X.; Eldholm, V.
10.1101/2023.08.02.551601 — microbiology — Posted on 2023-08-02
4310 Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress
Mikati, M. O.; Erdmann-Gilmore, P.; Connors, R.; Conway, S. M.; Malone, J.; Woods, J.; Sprung, R. W.; Townsend, R. R.; Al-Hasani, R.
10.1101/2023.02.15.528745 — neuroscience — Posted on 2023-08-02
4312 ZmPILS6 is an auxin efflux carrier required for maize root morphogenesis
Cowling, C. L.; Homayouni, A.; Callwood, J. B.; McReynolds, M. R.; Khor, J.; Ke, H.; Draves, M. A.; Dehesh, K.; Walley, J. W.; Strader, L. C.; Kelley, D. R.
10.1101/2023.08.01.551510 — plant biology — Posted on 2023-08-02
4315 PHOTOSYNTHESIS DRIVES RETENTION OF BACTERIAL-LIKE TRNA METABOLISM IN PLANT ORGANELLES
DeTar, R. A.; Chustecki, J.; Martinez-Hottovy, A.; Cerrioti, L. F.; Broz, A. K.; Sanchez-Puerta, M. V.; Elowsky, C.; Christensen, A. C.; Sloan, D. B.
10.1101/2023.08.01.551541 — plant biology — Posted on 2023-08-02
4317 Single-cell RNA sequencing reveals characteristics of myeloid cells in pulmonary post-acute sequelae of SARS-CoV-2
Yoon, H.; Dean, L. S.; Jiyarom, B.; Khadka, V.; Deng, Y.; Nerurkar, V. R.; Chow, D.; Shikuma, C.; Devendra, G.; Koh, Y.; Park, J.
10.1101/2023.07.31.551349 — microbiology — Posted on 2023-08-02
4318 Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses
Lee, A.; Floyd, K.; Wu, S.-Y.; Fang, Z.; Tan, T. K.; Li, C.; Hui, H.; Scoville, D.; Ruggiero, A.; Liang, Y.; Pavenko, A.; Lujan, V.; Nolan, G. P.; Arunachalam, P.; Suthar, M.; Pulendran, B.
10.1101/2023.07.31.551354 — immunology — Posted on 2023-08-02
4319 Strong immunogenicity & protection in mice with PlaCCine: A COVID-19 DNA vaccine formulated with a functional polymer
Sood, S.; Matar, M.; Kim, J.; Kinsella, M.; Rayavara, K.; Signer, O.; Henderson, J.; Smith, A.; Rogers, J.; Chawla, B.; Van Ry, A.; Narvaez, B.; Kar, S.; Arnold, A.; Su, D.; Rice, J.; Sparks, J.; Le Goff, C.; Boyer, J. D.; Anwer, K.
10.1101/2023.08.01.551509 — immunology — Posted on 2023-08-02
4320 Gonadal androgens are associated with decreased type I interferon production by pDCs and increased IgG titres to BNT162b2 following co-vaccination with live attenuated influenza vaccine in adolescents
Sampson, O. L.; Jay, C.; Adland, E.; Csala, A.; Lim, N.; Ebbrecht, S. M.; Gilligan, L. C.; Taylor, A. E.; George, S. S.; Longet, S.; Jones, L. C.; Barnes, E.; Frater, J.; Klenerman, P.; Dunachie, S.; Carroll, M. W.; Hawley, J.; Arlt, W.; Groll, A.; Goulder, P.
10.1101/2023.08.01.551423 — immunology — Posted on 2023-08-02
4325 Foveated metamers of the early visual system
Broderick, W. F.; Rufo, G.; Winawer, J.; Simoncelli, E.
10.1101/2023.05.18.541306 — neuroscience — Posted on 2023-08-02
4326 Temporal Dynamics of Normalization Reweighting
Baker, D. H.; Marinova, D.; Aveyard, R.; Hargreaves, L. J.; Renton, A.; Castellani, R.; Hall, P.; Harmens, M.; Holroyd, G.; Nicholson, B.; Williams, E. L.; Hobson, H. M.; Wade, A. R.
10.1101/2023.02.10.527994 — neuroscience — Posted on 2023-08-02
4328 Spatial Co-transcriptomics Reveals Discrete Stages of the Arbuscular Mycorrhizal Symbiosis
Serrano, K.; Bezrutczyk, M.; Goudeau, D.; Dao, T.; O'Malley, R. C.; Malmstrom, R. R.; Visel, A.; Scheller, H. V.; Cole, B.
10.1101/2023.08.02.551648 — plant biology — Posted on 2023-08-02
4332 Sex-specific adaptations to VTA circuits following subchronic stress
Bouarab, C.; Wynalda, M.; Thompson, B. V.; Khurana, A.; Cody, C. R.; Kisner, A.; Polter, A. M.
10.1101/2023.08.02.551665 — neuroscience — Posted on 2023-08-02
4334 The relationship between diet, plasma glucose, and cancer prevalence across vertebrates
Kapsetaki, S. E.; Basile, A. J.; Compton, Z. T.; Rupp, S. M.; Duke, E. G.; Boddy, A. M.; Harrison, T. M.; Sweazea, K. L.; Maley, C. C.
10.1101/2023.07.31.551378 — cancer biology — Posted on 2023-08-02
4336 MousiPLIER: A Mouse Pathway-Level Information Extractor Model
Zhang, S.; Heil, B. J.; Mao, W.; Greene, C. S.; Heller, E. A.
10.1101/2023.07.31.551386 — bioinformatics — Posted on 2023-08-02
4338 Blueberry and cranberry pangenomes as a resource for future genetic studies and breeding efforts
Yocca, A. E.; Platts, A.; Alger, E.; Teresi, S.; Mengist, M. F.; Benevenuto, J.; Felipe V. Ferrao, L.; Jacobs, M.; Babinski, M.; Magallanes-Lundback, M.; Bayer, P.; Golicz, A.; Humann, J. L.; Main, D.; Espley, R. V.; Chagne, D.; Albert, N. W.; Montanari, S.; Vorsa, N.; Polashock, J.; Diaz-Garcia, L.; Zalapa, J.; Bassil, N. V.; Munoz, P. R.; Iorizzo, M.; Edger, P. P.
10.1101/2023.07.31.551392 — genomics — Posted on 2023-08-02
4340 Clearwing butterflies challenge the thermal melanism hypothesis
Ossola, V.; Pottier, F.; Pinna, C.; Bougiouri, K.; Tournie, A.; Michelin, A.; Andraud, C.; Gomez, D.; Elias, M.
10.1101/2023.07.31.550889 — evolutionary biology — Posted on 2023-08-02
4342 Genomic analysis supports Cape Lion population connectivity prior to colonial eradication and extinction
de Flamingh, A.; Gnoske, T. P.; Rivera-Colon, A. G.; Simeonovski, V. A.; Kerbis Peterhans, J. C.; Yamaguchi, N.; Witt, K. E.; Catchen, J. M.; Roca, A.; Malhi, R. S.
10.1101/2023.07.31.551389 — evolutionary biology — Posted on 2023-08-02
4345 Myogenetic oligodeoxynucleotide induces myocardial differentiation of murine pluripotent stem cells
Ishioka, M.; Nihashi, Y.; Sunagawa, Y.; Umezawa, K.; Shimosato, T.; Kagami, H.; Morimoto, T.; Takaya, T.
10.1101/2023.07.31.551374 — cell biology — Posted on 2023-08-02
4346 The Crk4-Cyc4 complex regulates G2 phase of apicomplexan endodyogeny
Hawkins, L. M.; Wang, C.; Chaput, D.; Batra, M.; Marsilia, C.; Awshah, D.; Suvorova, E.
10.1101/2023.07.31.551351 — cell biology — Posted on 2023-08-02
4347 The ciliary MBO2 complex targets assembly of inner arm dynein b and reveals additional doublet microtubule asymmetries
Fu, G.; Augspurger, K.; Sakizadeh, J.; Reck, J.; Bower, R.; Tritschler, D.; Gui, L.; Nicastro, D.; Porter, M. E.
10.1101/2023.07.31.551375 — cell biology — Posted on 2023-08-02
4348 IST1 regulates select endosomal recycling pathways
Clippinger, A. K.; Naismith, T. V.; Yoo, W.; Jansen, S.; Kast, D.; Hanson, P. I.
10.1101/2023.07.31.551359 — cell biology — Posted on 2023-08-02
4349 Fatty links between multisystem proteinopathy and Small VCP-Interacting Protein
Ramzan, F.; Abrar, F.; Kumar, A.; Liao, L. M. Q.; Campbell, Z. E.; Gray, R. V.; Akanni, O.; Guyn, C. M.; Martin, D. D. O.
10.1101/2023.03.31.531359 — cell biology — Posted on 2023-08-02
4350 Retrotransposon addiction promotes centromere function via epigenetically activated small RNAs
Shimada, A.; Cahn, J.; Ernst, E.; Lynn, J.; Grimanelli, D.; Henderson, I. R.; Kakutani, T.; Martienssen, R. A.
10.1101/2023.08.02.551486 — molecular biology — Posted on 2023-08-02
4352 Where top-down meets bottom-up: Cell-type specific connectivity map of the whisker system
Rault, N.; Bergmans, T.; Delfstra, N.; Kleijnen, B. J.; Zeldenrust, F.; Celikel, T.
10.1101/2023.07.31.551377 — neuroscience — Posted on 2023-08-02
4354 Psychopathic traits predict neural responses to emotional movies in the general population
Aksiuto, A. K.; Lahnakoski, J.; Kauttonen, J.; Saarimaki, H. K.; Volynets, S.; Nummenmaa, L.; Sams, M.; Jaaskelainen, I.
10.1101/2023.07.31.551268 — neuroscience — Posted on 2023-08-02
4355 Eelbrain: A Python toolkit for time-continuous analysis with temporal response functions
Brodbeck, C.; Das, P.; Gillis, M.; Kulasingham, J. P.; Bhattasali, S.; Gaston, P.; Resnik, P.; Simon, J. Z.
10.1101/2021.08.01.454687 — neuroscience — Posted on 2023-08-02
4357 Electrical Brain Activity during Human Walking with Parametric Variations in Terrain Unevenness and Walking Speed
Liu, C.; Downey, R. J.; Salminen, J. S.; Rojas, S. A.; Richer, N.; Pliner, E. M.; Hwang, J.; Cruz-Almeida, Y.; Manini, T. M.; Hass, C. J.; Seidler, R. D.; Clark, D. J.; Ferris, D. P.
10.1101/2023.07.31.551289 — neuroscience — Posted on 2023-08-02
4358 In vivo characterization of a secologanin transporter from Catharanthus roseus
Li, F.; Shahsavarani, M.; Handy-Hart, C.-J.; Montgomery, V.; Beech, R. N.; Liu, L.; Bayen, S.; Qu, Y.; De Luca, V.; Dastmalchi, M.
10.1101/2023.08.01.551495 — plant biology — Posted on 2023-08-02
4359 DePARylation is critical for S phase progression and cell survival
Nie, L.; Wang, C.; Liu, X.; Huang, M.; Feng, X.; Tang, M.; Li, S.; Hang, Q.; Teng, H.; Shen, X.; Ma, L.; Gan, B.; Chen, J.
10.1101/2023.07.31.551317 — cancer biology — Posted on 2023-08-02
4360 EZH2 inhibition sensitizes IDH1R132H mutant gliomas to histone deacetylase inhibitor.
Sprinzen, L.; Garcia, F. G.; Mela, A.; Lei, L.; Upadhyayula, P.; Mahajan, A.; Humala, N.; Manier, L.; Caprioli, R. M.; Quinones-Hinojosa, A.; Casaccia, P.; Canoll, P.
10.1101/2023.07.31.551045 — cancer biology — Posted on 2023-08-02
4362 Autoinhibition in the Signal Transducer CIN85 Modulates B Cell Activation
Sieme, D.; Engelke, M.; Rezaei-Ghaleh, N.; Becker, S.; Wienands, J.; Griesinger, C.
10.1101/2023.07.31.551229 — biophysics — Posted on 2023-08-02
4364 Thinner is not always better: Optimising cryo lamellae for subtomogram averaging
Tuijtel, M. W.; Kreysing, J. P.; Welsch, S.; Hummer, G.; Beck, M.; Turonova, B.
10.1101/2023.07.31.551274 — biophysics — Posted on 2023-08-02
4365 Niclosamide potentiates TMEM16A and induces vasoconstriction
Liang, P.; Wan, Y. C. S.; Yu, K.; Hartzell, H. C.; Yang, H.
10.1101/2023.07.31.551400 — biophysics — Posted on 2023-08-02
4368 Genomic DNA extraction optimization and validation for genome sequencing using the marine gastropod Kellet's whelk
Daniels, B. N.; Nurge, J.; Sleeper, O.; Lee, A.; Lopez, C.; Christie, M.; Toonen, R. J.; Davidson, J.; White, C.
10.1101/2023.07.31.551321 — genomics — Posted on 2023-08-02
4369 The Interferon gamma Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming
Barrero, M.; Lopez-Rubio, A. V.; Lazarenkov, A.; Blanco, E.; Bauer, M.; Palma, L. G.; Bigas, A.; Di Croce, L.; Sardina, J. L.; Payer, B.
10.1101/2023.07.31.551297 — genetics — Posted on 2023-08-02
4371 Prions in carnivore feces: recovery from spiking experiments and detection in free-ranging carnivores
Inzalaco, H. N.; Brandell, E. E.; Wilson, S. P.; Hunsaker, M.; Stahler, D. R.; Woelfel, K.; Walsh, D. P.; Nordeen, T.; Storm, D. J.; Lichtenberg, S. S.; Turner, W. C.
10.1101/2023.07.31.551307 — ecology — Posted on 2023-08-02
4372 Dynamic proximity interaction profiling suggests that YPEL2 is involved in cellular stress surveillance
Turan, G.; Olgun, C. E.; Ayten, H.; Toker, P.; Ashyralyyev, A.; Savas, B.; Karaca, E.; Muyan, M.
10.1101/2023.07.31.551286 — cell biology — Posted on 2023-08-02
4374 Intra-host variation in the spike S1/S2 region of a feline coronavirus type-1 in a cat with persistent infection
Olarte-Castillo, X. A.; Licitra, B. N.; Andre, N. M.; Sierra, M. A.; Mason, C. E.; Goodman, L. B.; Whittaker, G.
10.1101/2023.07.31.551356 — molecular biology — Posted on 2023-08-02
4375 Comparative Analysis of Methods to Reduce Activation Signature Gene Expression in PBMCs
Andriamboavonjy, L.; MacDonald, A.; Hamilton, L. K.; Labrecque, M.; Boivin, M.-N.; Karamchandani, J.; Stratton, J. A.; Tetreault, M.
10.1101/2023.07.31.549036 — immunology — Posted on 2023-08-02
4376 Resolvin E1 improves efferocytosis and rescues severe aplastic anemia in mice
Grazda, R.; Seyfried, A. N.; Maddipatti, K. R.; Fredman, G.; MacNamara, K. C.
10.1101/2023.02.15.528688 — immunology — Posted on 2023-08-02
4377 Supervised White Matter Bundle Segmentation in Glioma Patients with Transfer Learning
Riccardi, C.; Ghezzi, S.; Amorosino, G.; Zigiotto, L.; Sarubbo, S.; Jovicich, J.; Avesani, P.
10.1101/2023.07.31.551318 — neuroscience — Posted on 2023-08-02
4379 The pelvic organs receive no parasympathetic innervation
Sivori, M.; Dempsey, B.; Chettouh, Z.; Boismoreau, F.; Ayerdi, M.; Eymael, A.; Baulande, S.; Lameiras, S.; Coulpier, F.; Delattre, O.; Rohrer, H.; Mirabeau, O.; Brunet, J.-F.
10.1101/2023.07.11.548500 — neuroscience — Posted on 2023-08-02
4383 Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancerous traits and oncogenic pathways shared among bilaterians
Burioli, E. A. V.; HAMMEL, M.; Vignal, E.; Vidal-Dupiol, J.; Mitta, G.; Thomas, F.; Bierne, N.; Destoumieux-Garzon, D.; Charriere, G. M.
10.1101/2023.01.03.522559 — cancer biology — Posted on 2023-08-02
4384 Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling
Li, C.; Allison, D. B.; He, D.; Mao, F.; Wang, X.; Rychahou, P.; Imam, I. A.; Kong, Y.; Zhang, Q.; Zhang, Y.; Liu, J.; Wang, R.; Rao, X.; Wu, S.; Shao, Q.; Wang, C.; Li, Z.; Liu, X.
10.1101/2023.07.31.551298 — cancer biology — Posted on 2023-08-02
4386 Elucidating the role of water in collagen self assembly by isotopically modulating collagen hydration
Giubertoni, G.; Feng, L.; Klein, K.; Giannetti, G.; Choi, Y.; van der Net, A.; Castro-Linares, G.; Caporaletti, F.; Micha, D.; Hunger, J.; Deblais, A.; Bonn, D.; Saric, A.; Ilie, I. M.; Koenderink, G. H.; Woutersen, S.
10.1101/2023.07.31.551300 — biophysics — Posted on 2023-08-02
4387 Local population structure in Cambridgeshire during the Roman occupation
Scheib, C. L.; Hui, R.; Rose, A. K.; Solnik, A.; D'Atanasio, E.; Inskip, S. A.; Cessford, C.; Griffith, S. J.; Wiseman, R.; Neil, B.; Biers, T.; Harknett, S.-J.; Sasso, S.; Biagini, S. A.; Runfeldt, G.; Duhig, C.; Evans, C.; O'Connell, T. C.; Metspalu, M.; Millett, M. J.; Robb, J. E.; Kivisild, T.
10.1101/2023.07.31.551265 — genetics — Posted on 2023-08-02
4391 Evolution of transient RNA structure-RNA polymerase interactions in respiratory RNA virus genomes
Rigby, C. V.; Sabsay, K. R.; Bisht, K.; Eggink, D.; Jalal, H.; te Velthuis, A. J. W.
10.1101/2023.05.25.542331 — microbiology — Posted on 2023-08-02
4392 Humoral correlates of protection against Mycobacterium tuberculosis following intravenous Bacille Calmette-Guerin vaccination in rhesus macaques
Irvine, E. B.; Darrah, P. A.; Wang, S.; Wang, C.; McNamara, R.; Roederer, M.; Seder, R. A.; Lauffenburger, D. A.; Flynn, J. L.; Fortune, S. M.; Alter, G.
10.1101/2023.07.31.551245 — immunology — Posted on 2023-08-02
4393 Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes
Starck, L.; Sarem, M.; Heimrich, B.; Sawarkar, R.; Ritz, M.-F.; Hutter, G.; Shastri, V. P.
10.1101/2023.07.31.551259 — neuroscience — Posted on 2023-08-02
4394 Reactivation strength during cued recall is modulated by graph distance within cognitive maps
Kern, S.; Nagel, J.; Gerchen, M. F.; Gürsoy, C.; Meyer-Lindenberg, A.; Kirsch, P.; Dolan, R. J.; Gais, S.; Feld, G. B.
10.1101/2023.07.31.551234 — neuroscience — Posted on 2023-08-02
4397 Propagation of neuronal micronuclei regulates microglial states
Yano, S.; Asami, N.; Kishi, Y.; Kubotani, H.; Hattori, Y.; Kitazawa, A.; Hayashi, K.; Kubo, K.-i.; Saeki, M.; Maeda, C.; Akiyama, K.; Okajima-Takahashi, T.; Sato, B.; Gotoh, Y.; Nakajima, K.; Ichinohe, T.; Nagata, T.; Chiba, T.; Tsuruta, F.
10.1101/2023.07.31.551211 — neuroscience — Posted on 2023-08-02
4398 CCT and Cullin1 regulate the TORC1 pathway to promote dendritic arborization in health and disease.
Lottes, E. N.; Ciger, F. H.; Bhattacharjee, S.; Timmins-Wilde, E. A.; Tete, B.; Tran, T.; Matta, J.; Patel, A. A.; Cox, D. N.
10.1101/2023.07.31.551324 — neuroscience — Posted on 2023-08-02
4400 IN VIVO ISOLATION OF A QUIESCENT MELANOMA POPULATION WITH INVASIVE PROPERTIES UNVEILS A TRANSCRIPTIONAL REPROGRAMMING DRIVEN BY THE TUMOR NICHE
Lanfrancone, L.; Lotti, F.; Meliksetyan, M.; Malferrari, M.; Quaresima, N.; Rapino, S.; Mollo, V.; Ferrarotto, I.; Vlachou, T.; Bossi, D.; Pelicci, P. G.; Luzi, L.
10.1101/2023.07.31.551214 — cancer biology — Posted on 2023-08-02
4401 Quantitative description of the phase separation behavior of the multivalent SLP65-CIN85 complex
Maier, J.; Sieme, D.; Wong, L. E.; Dar, F.; Wienands, J.; Becker, S.; Griesinger, C.
10.1101/2023.07.31.551239 — biophysics — Posted on 2023-08-02
4405 Childhood-onset asthma is characterized by airway epithelial hillock-to-squamous differentiation in early life
Kersten, E. T. G.; Pett, J. P.; Malmstrom, K.; Chun, Y.; Jonker, M. R.; Wilbrey-Clark, A. L.; Worlock, K. B.; van den Berge, M.; Vermeulen, R. C. H.; Vonk, J. M.; Sebire, N.; Lohi, J.; Timens, W.; Teichmann, S.; Bunyavanich, S.; Nikolic, M. Z.; Nawijn, M. C.; Makela, M.; Meyer, K. B.; Koppelman, G. H.
10.1101/2023.07.31.549680 — genomics — Posted on 2023-08-02
4407 Evolution of alternative reproductive systems in Bacillus stick insects
Lavanchy, G.; Brandt, A.; Bastardot, M.; Dumas, Z.; Labedan, M.; Massy, M.; Toubiana, W.; TranVan, P.; Luchetti, A.; Scali, V.; Mantovani, B.; Schwander, T.
10.1101/2023.07.31.550487 — evolutionary biology — Posted on 2023-08-02
4410 Modeling individual variability in habitat selection and movement using integrated step-selection analyses
Chatterjee, N.; Wolfson, D.; Kim, D.; Gomez, J. V.; Freeman, S.; Bacheler, N. M.; Shertzer, K.; Fieberg, J.
10.1101/2023.07.31.551213 — ecology — Posted on 2023-08-02
4411 Sequencing and chromosome-scale assembly of the giant Pleurodeles waltl genome
Brown, T.; Elewa, A.; Iarovenko, S.; Subramanian, E.; Joven Araus, A.; Petzold, A.; Suzuki, M.; Suzuki, K.-i.; Hayashi, T.; Toyoda, A.; Oliveira, C.; Osipova, E.; Leigh, N.; Simon, A.; Yun, M.
10.1101/2022.10.19.512763 — developmental biology — Posted on 2023-08-02
4412 Induced pluripotent stem cell-derived human macrophages as an infection model for Leishmania donovani
Baert, L.; Rudy, S.; Pellisson, M.; Doll, T.; Rocchetti, R.; Kaiser, M.; Mäser, P.; Müller, M.
10.1101/2023.07.31.551225 — cell biology — Posted on 2023-08-02
4413 NK cell-induced damage to P. falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG
Sekar, P.; Rajagopalan, S.; Shabani, E.; Kanjee, U.; Schurek, M.; Arora, G.; Peterson, M. E.; Traore, B.; Crompton, P. D.; Duraisingh, M. T.; Desai, S. A.; Long, E. O.
10.1101/2023.07.31.551226 — immunology — Posted on 2023-08-02
4414 MiR-155 epigenetically counteracts hypoxia for mitochondrial fitness during germinal center positive selection
Nakagawa, R.; Llorian-Sopena, M.; Varsani-brown, S.; Chakravarty, P.; Camarillo, J. M.; Barry, D.; George, R.; Blackledge, N. P.; Duddy, G.; Klose, R.; Turner, M.; Calado, D. P.
10.1101/2023.07.31.551250 — immunology — Posted on 2023-08-02
4418 Multiscale Rheology of Aging Cancer Spheroids
Gnanachandran, K.; Berardi, M.; Skar, A.; Pyka-Fosciak, G.; Pabijan, J.; Lopez Alonso, J.; B. Akca, I.; Lekka, M.
10.1101/2023.07.31.550652 — biophysics — Posted on 2023-08-02
4420 Sale of critically endangered sharks in the United States
Ryburn, S. J.; Yu, T.; Ong, K. J.-W.; Alston, M. A.; Howie, E.; LeRoy, P.; Giang, S. E.; Ball, W.; Benton, J.; Calhoun, R.; Favreau, I.; Gutierrez, A.; Hallac, K.; Hanson, D.; Hibbard, T.; Loflin, B.; Lopez, J.; Mock, G.; Myers, K.; Pinos-Sanchez, A.; Suarez Garcia, A. M.; Romero, A. R.; Thomas, A.; Williams, R.; Zaldivar, A.; Bruno, J. F.
10.1101/2023.07.30.551124 — genetics — Posted on 2023-08-02
4422 Mitochondrial Ca2+ uniporter (MCU) variants form plasma-membrane channels
Polina, I.; Mishra, J.; Cypress, M. W.; Landherr, M.; Valkov, N.; Chaput, I.; Nieto, B.; Mende, U.; Zhang, P.; Jhun, B. S.; O-Uchi, J.
10.1101/2023.07.31.551242 — cell biology — Posted on 2023-08-02
4423 The infectivity of SARS-CoV-2 progeny virions requires the activity of host cell N-myristoyltransferases and it is severely compromised by their inhibition
Saber, S. H.; Ojha, R.; Quirin, T.; Ruuska, J.; Strandin, T.; Yak, N.; Kant, R.; Kareinen, L.; Sironen, T.; Vapalahti, O.; Balistreri, G.; Joensuu, M.
10.1101/2023.03.03.530798 — microbiology — Posted on 2023-08-02
4425 Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.
Langer, H. T.; Ramsamooj, S.; Dantas, E.; Murthy, A.; Ahmed, M.; Hwang, S.-K.; Grover, R.; Pozovskiy, R.; Liang, R. J.; Queiroz, A. L.; Brown, J. C.; White, E. P.; Janowitz, T.; Goncalves, M. D.
10.1101/2023.07.31.551241 — cancer biology — Posted on 2023-08-02
4427 Screening for variable drug responses using human iPSC cohorts
Platani, M.; Jiang, H.; Davidson, L.; Hariharan, S.; Doyonnas, R.; Lamond, A. I.; Swedlow, J. R.
10.1101/2023.06.16.545161 — cell biology — Posted on 2023-08-02
4430 Three-Dimensional Mitochondria Reconstructions of Murine Cardiac Muscle Changes in Size Across Aging
Vue, Z.; Neikirk, K.; Vang, L.; Garza-Lopez, E.; Christensen, T. A.; Shao, J.-q.; Lam, J.; Beasley, H. K.; Marshall, A. G.; Crabtree, A.; Anudokem, J.; Rodriguez, B.; Kirk, B.; Bacevac, S.; Barongan, T.; Shao, B.; Stephens, D. C.; Kabugi, K.; Koh, H.-J.; Koh, A.; Evans, C. S.; Taylor, B. T.; Reddy, A. K.; Miller-Fleming, T.; Actkins, K. V.; Zaganjor, E.; Daneshgar, N.; Murray, S. A.; Mobley, B. C.; Damo, S. M.; Gaddy, J. A.; Riggs, B.; Wanjalla, C.; Kirabo, A.; McReynolds, M.; Gomez, J. A.; Phillips, M. A.; Exil, V.; Dai, D.-F.; Hinton, A.
10.1101/2022.04.23.489291 — biophysics — Posted on 2023-08-02
4431 ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota
Cheng, M.-y.; Xu, B.; Sun, Y.; Wang, J.; Lu, Y.; Shi, C.; Pan, T.; Zhao, W.; Li, X.; Song, X.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Yang, D.; Wang, C.; Cao, X.
10.1101/2023.07.30.551192 — immunology — Posted on 2023-08-02
4433 Multiomics responses to seasonal variations in diel cycles in the marine phytoplanktonic picoeukaryote Ostreococcus tauri
Romero-Losada, A. B.; Arvanitidou, C.; Garcia-Gomez, M. E.; Morales-Pineda, M.; Castro-Perez, M. J.; Garcia-Gonzalez, M.; Romero-Campero, F. J.
10.1101/2023.07.31.551326 — plant biology — Posted on 2023-08-02
4435 Detection of a reservoir of bedaquiline / clofazimine resistance associated variants in Mycobacterium tuberculosis predating the antibiotic era
van Dorp, L.; Nimmo, C.; Torres Ortiz, A.; Pang, J.; Acman, M.; Tan, C. C.; Millard, J.; Padayatchi, N.; Grant, A.; O'Donnell, M. R.; Pym, A.; Brynildsrud, O. B.; Eldholm, V.; Grandjean, L.; Didelot, X.; Balloux, F.
10.1101/2020.10.06.328799 — genomics — Posted on 2023-08-02
4436 Changes driven by the evolution of higher group polarization in the guppy are consistent across different predation pressures and associated with neuroanatomical changes
Corral-Lopez, A.; Kotrschal, A.; Szorkovszky, A.; Garate-Olaizola, M.; Herbert-Read, J.; van der Bijl, W.; Romenskyy, M.; Zeng, H.-L.; Buechel, S. D.; Fontrodona-Eslava, A.; Pelckmans, K.; Mank, J. E.; Kolm, N.
10.1101/2022.09.07.506928 — evolutionary biology — Posted on 2023-08-02
4437 Circadian ribosome profiling reveals a role for the Period2 upstream open reading frame in sleep
Millius, A.; Yamada, R.; Fujishima, H.; Maeda, K.; Standley, D. M.; Sumiyama, K.; Perrin, D.; Ueda, H. R.
10.1101/2022.08.09.503391 — cell biology — Posted on 2023-08-02
4438 Epigenetic modifications driving ground state pluripotency exit require an NF-κB-independent chromatin IκBα function
Galan, L.; Alvarez-Villanueva, D.; Maqueda, M.; Barrero, M.; IGLESIAS, A.; Bertran, j.; ALVAREZ, D.; GARCIA-PRIETO, C.; BALLARE, C.; RODRIGUEZ-CORTEZ, V.; BUENO, C.; VIDAL, A.; Villanueva, A.; Menendez, P.; Di Croce, L.; Payer, B.; Esteller, M.; Espinosa, L.; Bigas, A.
10.1101/2023.07.28.550934 — cell biology — Posted on 2023-08-02
4439 Recruitment of TRiC chaperonin in rotavirus viroplasms directly associates with virus replication.
Vetter, J.; Papa, G.; Tobler, K.; Kley, M.; Myers, M.; Wiesendanger, M.; Schraner, E. M.; Burrone, O. R.; Fraefel, C.; Eichwald, C.
10.1101/2022.12.13.520363 — microbiology — Posted on 2023-08-02
4440 High arousal disrupts the neural signatures of conflict processing but not behavioural performance
Avancini, C.; Ciria, L. F.; Alameda, C.; Palenciano, A. F.; Canales-Johnson, A.; Bekinschtein, T. A.; Sanabria, D.
10.1101/2023.07.31.550835 — neuroscience — Posted on 2023-08-02
4441 ddRAD-seq-derived SNPs reveal novel association signatures for fruit-related traits in peach
Ksouri, N.; Sanchez, G.; Font i Forcada, C.; Contreras-Moreira, B.; Gogorcena, Y.
10.1101/2023.07.31.551252 — plant biology — Posted on 2023-08-02
4442 Defining Mitochondrial Cristae Morphology Changes Induced by Aging in Brown Adipose Tissue
Crabtree, A.; Neikirk, K.; Marshall, A.; Vang, L.; Stephens, D.; Shao, B.; Garza-Lopez, E.; Lam, J.; Rodriguez, B.; Mungai, M.; Stanley, J.; Dean, D.; Gaddy, J.; Scudese, E.; Sweetwyne, M.; Davis, J.; Zaganjor, E.; Murray, S.; Katti, P.; Damo, S.; Vue, Z.; Hinton, A.
10.1101/2023.05.12.540609 — biophysics — Posted on 2023-08-02
4445 Long-term impact of early life stress on serotonin connectivity
Ramkumar, R.; Edge-Partington, M.; Adigun, K.; Ren, Y.; Terstege, D. J.; Khan, N. S.; Rouhi, N.; Jamani, N. F.; Tsutsui, M.; Epp, J. R.; Sargin, D.
10.1101/2023.08.01.551573 — neuroscience — Posted on 2023-08-02
4446 Recognition of Necrosis and Ethylene-inducing like peptides confers disease resistance in Brassica napus and is modulated by BSK1 in Arabidopsis
Yalcin, H. A.; Ramirez Gonzalez, R. H.; Jacott, C. N.; Steuernagel, B.; Sidhu, G. S.; Kirby, R.; Verbeek, E.; Schoonbeek, H.-j.; Ridout, C.; Wells, R.
10.1101/2023.08.01.551450 — plant biology — Posted on 2023-08-02
4448 Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis
Clayton, B. L. L.; Barbar, L.; Sapar, M.; Rusielewicz, T.; Kalpana, K.; Migliori, B.; The NYSCF Global Stem Cell Array, ; Paull, D.; Brenner, K.; Moroziewicz, D.; Sand, I. K.; Casaccia, P.; Tesar, P. J.; Fossati, V.
10.1101/2023.08.01.551553 — neuroscience — Posted on 2023-08-02
4452 A feedback control mechanism governs the synthesis of lipid-linked precursors of the bacterial cell wall
Marmont, L. S.; Orta, A. K.; Corey, R. A.; Sychantha, D.; Fernandez-Galliano, A.; Li, Y. E.; Baileeves, B. W.; Greene, N. G.; Stansfeld, P. J.; Clemons, W. M.; Bernhardt, T. G.
10.1101/2023.08.01.551478 — microbiology — Posted on 2023-08-01
4454 Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
Chew, B. L. A.; Ngoh, A. Q.; Phoo, W. W.; Chan, W. K. K.; Zheng, S.; Tulsian, N. K.; Lim, S. S.; Weng, M. J. G.; Watanabe, S.; Choy, M. M.; Low, G. H. J.; Ooi, E. E.; Ruedl, C.; SOBOTA, R. M.; Vasudevan, S. G.; Luo, D.
10.1101/2022.04.06.487425 — microbiology — Posted on 2023-08-01
4457 One-Step Selective Labeling of Native Cell-Surface Sialoglycans by Exogenous α2,8-Sialylation
Babulic, J. L.; Kofsky, J. M.; Boddington, M. E.; Kim, Y.; Leblanc, E. V.; Emberley-Korkmaz, S.; Colpitts, C. C.; Capicciotti, C. J.
10.1101/2023.08.01.551455 — biochemistry — Posted on 2023-08-01
4461 De novo Protein Sequence Design Based on Deep Learning and Validation on CalB Hydrolase
Mu, J.; Li, Z.; Zhang, B.; Zhang, Q.; Iqbal, J.; Wadood, A.; Wei, T.; Feng, Y.; Chen, H.
10.1101/2023.08.01.551444 — biochemistry — Posted on 2023-08-01
4462 Multi-omic temporal landscape of plasma and synovial fluid-derived extracellular vesicles using an experimental model of equine osteoarthritis
Anderson, J. R.; Johnson, E.; Jenkins, R.; Jacobsen, S.; Green, D.; Walters, M.; Bundgaard, L.; Hausmans, B. A.; van den Akker, G.; Welting, T. J.; Chabronova, A.; Kharaz, Y. A.; Clarke, E. J.; James, V.; Peffers, M. J.
10.1101/2023.08.01.551464 — molecular biology — Posted on 2023-08-01
4464 Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
Lang, M.; Renard, S.; El-Meouche, I.; Amoura, A.; Denamur, E.; Brosschot, T.; Ingersoll, M.; Bacque, E.; Mazel, D.; Baharoglu, Z.
10.1101/2023.07.31.551273 — microbiology — Posted on 2023-08-01
4465 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome
Krischuns, T.; Arragain, B.; Isel, C.; Paisant, S.; Budt, M.; Wolff, T.; Cusack, S.; Naffakh, N.
10.1101/2023.08.01.551436 — microbiology — Posted on 2023-08-01
4468 Borg extrachromosomal elements of methane-oxidizing archaea have conserved and expressed genetic repertoires
Schoelmerich, M. C.; Ly, L.; West-Roberts, J.; Shi, L.-D.; Shen, C.; Malvankar, N.; Taib, N.; Gribaldo, S.; Woodcroft, B. J.; Al-Shayeb, B.; Dai, X.; Mozsary, C.; Hickey, S.; He, C.; Beaulaurier, J. A.; Juul, S.; Sachdeva, R.; Banfield, J.
10.1101/2023.08.01.549754 — microbiology — Posted on 2023-08-01
4469 Pan-species transcriptomic analysis reveals a constitutive adaptation against oxidative stress for the highly virulent Leptospira species.
Giraud Gatineau, A.; Ayachit, G.; Nieves, C.; Dagbo, C.; Bourhy, K.; Pulido, F.; Huete, S.; Benaroudj, N.; Picardeau, M.; Veyrier, F. J.
10.1101/2023.08.01.551416 — microbiology — Posted on 2023-08-01
4470 Serpine1 negatively regulates Th1 cell responses in experimental autoimmune encephalomyelitis.
Akbar, I.; Tang, R.; Baillargeon, J.; Roy, A.-P.; Doss, P. M. I. A.; Zhu, C.; Kuchroo, V. K.; Rangachari, M.
10.1101/2023.07.13.548887 — immunology — Posted on 2023-08-01
4478 Targeted Amplification and Genetic Sequencing of the Severe Acute Respiratory Syndrome Coronavirus 2 Surface Glycoprotein
Keller, M. W.; Keong, L. M.; Rambo-Martin, B. L.; Hassell, N.; Lacek, K.; Wilson, M. M.; Kirby, M. K.; Liddell, J.; Owuor, D. C.; Sheth, M.; Madden, J.; Lee, J. S.; Kondor, R. J.; Wentworth, D. E.; Barnes, J. R.
10.1101/2023.07.28.551051 — genomics — Posted on 2023-08-01
4480 Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning
Meehan, G. R.; Herder, V.; Allan, J.; Huang, X.; Kerr, K.; Mendonca, D. C.; Ilia, G.; Wright, D.; Nomikou, K.; Gu, Q.; Arias, S. M.; De Lorenzo, G.; Cowton, V.; Upfold, N.; Palmalux, N.; Brown, J. C.; Barclay, W.; Filipe, A. D. S.; Furnon, W.; Patel, A.; Palmarini, M.
10.1101/2023.08.01.551417 — microbiology — Posted on 2023-08-01
4481 Epigenetic liquid biopsies reveal elevated vascular endothelial cell turnover and erythropoiesis in asymptomatic COVID-19 patients
Ben Ami, R.; Loyfer, N.; Cohn, E.; Fialkoff, G.; Sharkia, I.; Bogot, N.; Kochan, D.; Kalak, G.; Jarjoui, A.; Chen-Shuali, C.; Azulai, H.; Barhoum, H.; Arish, N.; Greenberger, M. M.; Velleman, D.; Kurd, R.; Chetrit, E. B.; Bohm, D.; Wolak, T.; Quteineh, A.; Cann, G.; Glaser, B.; Friedman, N.; Kaplan, T.; Shemer, R.; Rokach, A.; Dor, Y.
10.1101/2023.07.28.550957 — microbiology — Posted on 2023-08-01
4484 Klebsiella pneumoniae Co-infection Leads to Fatal Pneumonia in SARS-CoV-2-infected Mice
Villalva, C.; Patil, G.; Narayanan, S.; Chanda, D.; Ghimire, R.; Snider, T.; Ramachandran, A.; Channappanavar, R.; More, S.
10.1101/2023.07.28.551035 — immunology — Posted on 2023-08-01
4485 Driving and suppressing the human language network using large language models
Tuckute, G.; Sathe, A.; Srikant, S.; Taliaferro, M.; Wang, M.; Schrimpf, M.; Kay, K.; Fedorenko, E.
10.1101/2023.04.16.537080 — neuroscience — Posted on 2023-08-01
4487 DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale
Firsanov, D.; Zacher, M.; Tian, X.; Zhao, Y.; George, J. C.; Sformo, T. L.; Tombline, G.; Biashad, S. A.; Gilman, A.; Hamilton, N.; Patel, A.; Straight, M.; Lee, M.; Lu, J. Y.; Haseljic, E.; Williams, A.; Miller, N.; Gladyshev, V. N.; Zhang, Z.; Vijg, J.; Seluanov, A.; Gorbunova, V.
10.1101/2023.05.07.539748 — cancer biology — Posted on 2023-08-01
4488 LipidSIM: inferring mechanistic lipid biosynthesis perturbations from lipidomics with a flexible, low-parameter, systematic Markov Modeling framework
Liang, C.; Murray, S.; Li, Y.; Lee, R.; Low, A.; Sasaki, S.; Chiang, W.-T.; Lin, W.-J.; Mathews, J.; Barnes, W.; Lewis, N. E.
10.1101/2023.07.26.550768 — bioinformatics — Posted on 2023-08-01
4489 Degenerative changes are associated with severity of anterior cruciate ligament injury within the skeletally immature joint
Howe, D.; Thompson, J. D.; Teeter, S. D.; Easson, M.; Barlow, O.; Griffith, E. H.; Schnabel, L. V.; Spang, J. T.; Fisher, M. B.
10.1101/2022.11.12.516262 — bioengineering — Posted on 2023-08-01
4491 Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats
Ishiwari, K.; King, C. P.; Martin, C. D.; Tripi, J. A.; George, A. M.; Lamparelli, A. C.; Chitre, A.; Polesskaya, O.; Richards, J. B.; Solberg Woods, L. C.; Gancarz, A.; Palmer, A. A.; Dietz, D. M.; Mitchell, S. H.; Meyer, P. J.
10.1101/2023.06.30.547228 — animal behavior and cognition — Posted on 2023-08-01
4492 Conserving a threatened North American walnut: a chromosome-scale reference genome for butternut (Juglans cinerea)
Guzman-Torres, C. R.; Trybulec, E.; LeVasseur, H.; Akella, H.; Amee, M.; Strickland, E.; Pauloski, N.; Williams, M.; Romero-Severson, J.; Hoban, S.; Woeste, K.; Pike, C.; Fetter, K. C.; Webster, C. N.; Neitzey, M. L.; O'Neill, R.; Wegrzyn, J. L.
10.1101/2023.05.12.539246 — genomics — Posted on 2023-08-01
4495 Growth directions and stiffness across cell layers determine whether tissues stay smooth or buckle
Yadav, A. S.; Hong, L.; Klees, P. M.; Kiss, A.; He, X.; Barrios, I. M.; Heeney, M.; Galang, A. M. D.; Smith, R. S.; Boudaoud, A.; Roeder, A. H. K.
10.1101/2023.07.22.549953 — developmental biology — Posted on 2023-08-01
4496 Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal
Pearson, M.; Haslam, C.; Fosberry, A.; Jones, E. J.; Reglinski, M.; Edwards, R. J.; Lawrenson, R. A.; Brown, J. C.; Mossakowska, D.; Pease, J. E.; Sriskandan, S.
10.1101/2021.11.14.468564 — microbiology — Posted on 2023-08-01
4501 ScreenDMT reveals linoleic acid diols replicably associate with BMI and stimulate adipocyte calcium fluxes
Dreyfuss, J. M.; Djordjilovic, V.; Pan, H.; Bussberg, V.; MacDonald, A. M.; Narain, N. R.; Kiebish, M. A.; Bluher, M.; Tseng, Y.-H.; Lynes, M. D.
10.1101/2023.07.12.548737 — bioinformatics — Posted on 2023-08-01
4502 Structure of Orthoreovirus RNA Chaperone σNS, a Component of Viral Replication Factories
Zhao, B.; Hu, L.; Kuandal, S.; Lee, C.; Somoulay, X.; Sankaran, B.; Taylor, G. M.; Dermody, T. S.; Prasad, B. V. V.
10.1101/2023.07.31.551319 — biochemistry — Posted on 2023-08-01
4504 Dendritic, delayed, and stochastic CaMKII activation underlies behavioral time scale plasticity in CA1 synapses
Jain, A.; Nakahata, Y.; Watabe, T.; Rusina, P.; South, K. E.; Adachi, K.; Yan, L.; Simorowski, N.; Furukawa, H.; Yasuda, R.
10.1101/2023.08.01.549180 — neuroscience — Posted on 2023-08-01
4505 Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model
Llambrich, S.; Tielemans, B.; Saliën, E.; Atzori, M.; Wouters, K.; Van Bulck, V.; Platt, M.; Vanherp, L.; Gallego Fernandez, N.; Grau de la Fuente, L.; Poptani, H.; Verlinden, L.; Himmelreich, U.; Croitor, A.; Attanasio, C.; Callaerts-Vegh, Z.; Gsell, W.; Martinez-Abadias, N.; Vande Velde, G.
10.1101/2023.07.31.551282 — systems biology — Posted on 2023-08-01
4507 Interdependence of a kinase and its cognate substrate plasma membrane nanoscale dynamics underlies Arabidopsis response to viral infection
JOLIVET, M.-D.; Deroubaix, A.-F.; Boudsocq, M.; Abel, N. B.; Rocher, M.; Robbe, T.; Wattelet, V.; Huard, J.; Lefebvre, D.; Lu, Y.-J.; Day, B.; Saias, G.; Ahmed, J.; Cotelle, V.; Giovinazzo, N.; Gallois, J.-L.; Yamaji, Y.; German-Retana, S.; Gronnier, J.; Ott, T.; MONGRAND, S.; Germain, V.
10.1101/2023.07.31.551174 — plant biology — Posted on 2023-08-01
4509 Multimodal sensory control of motor performance by glycinergic interneurons of the spinal cord deep dorsal horn.
Gradwell, M. A.; Ozeri-Engelhard, N.; Eisdorfer, J. T.; Laflamme, O. D.; Gonzalez, M.; Upadhyay, A.; Aoki, A.; Shrier, T.; Gandhi, M.; Abbas- Zadeh, G.; Oputa, O.; Thackray, J.; Ricci, M.; Yusuf, N.; Keating, J.; Bohic, M.; Imtiaz, Z.; Alomary, S. A.; Katz, J.; Haas, M.; Hernandez, Y.; Akay, T.; Abraira, V. E.
10.1101/2022.05.21.492933 — neuroscience — Posted on 2023-08-01
4512 Ligand bias underlies differential signaling of multiple FGFs via FGFR1
Karl, K. A.; Hristova, K.; Krejci, P.; Del Piccolo, N.; Light, T.; Roy, T.; Dudeja, P.; Ursachi, V.-C.; Fafilek, B.
10.1101/2022.01.06.475273 — biophysics — Posted on 2023-08-01
4514 Msh2-Msh3 interferes with DNA metabolism in vivo
Medina-Rivera, M.; Phelps, S.; Sridharan, M.; Becker, J.; Lamb, N. A.; Kumar, C.; Sutton, M. D.; Bielinsky, A. K.; Balakrishnan, L.; Surtees, J. A.
10.1101/2022.09.06.506750 — genetics — Posted on 2023-08-01
4516 Defining transcription factor nucleosome binding with Pioneer-seq
Tsompana, M.; Wilson, P.; Murugaiyan, V.; Handelmann, C.; Buck, M. J.
10.1101/2022.11.11.516133 — molecular biology — Posted on 2023-08-01
4518 Iron rescues glucose-mediated photosynthesis repression during lipid accumulation in the green alga Chromochloris zofingiensis
Jeffers, T. L.; Purvine, S. O.; Nicora, C. D.; McCombs, R. M.; Upadhyaya, S. L.; Stroumza, A.; Whang, K.; Gallaher, S. D.; Dohnalkova, A.; Merchant, S.; Lipton, M.; Niyogi, K. K.; Roth, M. S.
10.1101/2023.07.31.551119 — plant biology — Posted on 2023-08-01
4519 SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status
Daley, B.; Vieira, H. M.; Rao, C.; Hughes, J. M.; Beckley, Z. M.; Huisman, D. H.; Chatterjee, D.; Sealover, N. E.; Cox, K.; Askew, J. W.; Svoboda, R. A.; Fisher, K. W.; Lewis, R. E.; Kortum, R. L.
10.1101/2022.12.06.519395 — cancer biology — Posted on 2023-08-01
4524 Spatiotemporal resonance in mouse primary visual cortex
Gulbinaite, R.; Nazari, M.; Rule, M. E.; Bermudez Contreras, E. J.; Cohen, M. X.; Heimel, J. A.; Mohajerani, M. H.
10.1101/2023.07.31.551212 — neuroscience — Posted on 2023-08-01
4525 Antagonism of kappa opioid receptors worsens the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion
Flores, A. J.; Bartlett, M. J.; Seaton, B. T.; Samtani, G.; Sexauer, M. R.; Weintraub, N. C.; Siegenthaler, J. R.; Lu, D.; Heien, M. L.; Porreca, F.; Sherman, S. J.; Falk, T.
10.1101/2023.07.31.551112 — neuroscience — Posted on 2023-08-01
4526 Oryza genera-specific novel Histone H4 variant predisposes H4 Lysine5 Acetylation marks to modulate salt stress responses
G, V. H. S.; Sotelo-Parrilla, P.; Raju, S.; Jha, S.; Gireesh, A.; Gut, F.; Kutti, V. R.; Berger, F.; Jeyaprakash, A. A.; Shivaprasad, P. V.
10.1101/2023.07.31.551207 — plant biology — Posted on 2023-08-01
4530 Functional convergence of genomic and transcriptomic genetic architecture underlying sociability in a live-bearing fish
Corral-Lopez, A.; Bloch, N. I.; van der Bijl, W.; Cortazar-Chinarro, M.; Szorkovszky, A.; Kotrschal, A.; Darolti, I.; Buechel, S. D.; Romenskyy, M.; Kolm, N.; Mank, J. E.
10.1101/2023.02.13.528353 — evolutionary biology — Posted on 2023-08-01
4532 Assessing The Impact Of Autologous Neutralizing Antibodies On Viral Rebound In Postnatally SHIV-Infected ART-Treated Infant Rhesus Macaques
Mainou, E.; Berendam, S. J.; Obregon-Perko, V.; Uffman, E. A.; Phan, C. T.; Shaw, G. M.; Bar, K. J.; Conway, J. M.; Chan, C.; Chahroudi, A. M.; McCarthy, J.; Permar, S. R.; Silvestri, G.; Siliciano, R. F.; Silicano, J.; Fouda, G. J.; Fray, E. J.; Kumar, M. R.
10.1101/2023.07.22.550159 — immunology — Posted on 2023-08-01
4536 Potential to Enhance Large Scale Molecular Assessments of Skin Photoaging through Virtual Inference of Spatial Transcriptomics from Routine Staining
Srinivasan, G.; Davis, M.; LeBoeuf, M.; Fatemi, M.; Azher, Z.; Lu, Y.; Diallo, A.; Montivero, M.; Kolling, F.; Perrard, L.; Salas, L.; Christensen, B.; Palisoul, S.; Tsongalis, G.; Vaickus, L.; Preum, S.; Levy, J.
10.1101/2023.07.30.551188 — pathology — Posted on 2023-08-01
4537 Clade-Specific MPXV PCR Assays
Negron, D. A.; Tolli, N.; Guertin, S.; Wollen-Roberts, S.; Mitchell, S.; Haas, J.; Pratt, C.; Jennings, K.; Abramson, B.; Brinkac, L.; Ashford, D.
10.1101/2023.04.24.538151 — bioinformatics — Posted on 2023-08-01
4538 Structure of Orthoreovirus RNA Chaperone σNS, a Component of Viral Replication Factories
Zhou, B.; Hu, L.; Kuandal, S.; Lee, C.; Somoulay, X.; Sankaran, B.; Taylor, G. M.; Dermody, T. S.; Prasad, B. V.
10.1101/2023.07.31.551319 — biochemistry — Posted on 2023-08-01
4540 Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSC.
Andrews, T. S.; Nakib, D.; Perciani, C.; Ma, X. Z.; Liu, L.; Winter, E.; Camat, D.; Chung, S.; Manuel, J.; Mangroo, S.; Hansen, B.; Arpinder, B.; Thoeni, C.; Sayed, B.; Feld, J.; Gehring, A.; Gulamhusein, A.; Hirschfield, G. M.; Rciutto, A.; Bader, G. D.; McGilvray, I. D.; MacParland, S. A.
10.1101/2023.07.28.550550 — cell biology — Posted on 2023-08-01
4542 Monitoring of drought stress and transpiration rate using proximal thermal and hyperspectral imaging in an indoor automated plant phenotyping platform
Mertens, S.; Verbraeken, L.; Sprenger, H.; De Meyer, S.; Demuynck, K.; Cannoot, B.; Merchie, J.; De Block, J.; Vogel, J. T.; Bruce, W.; Nelissen, H.; Maere, S. G.; Inze, D.; Wuyts, N.
10.1101/2023.08.01.551261 — plant biology — Posted on 2023-08-01
4545 Comparative abundance and diversity of populations of the Pseudomonas syringae and Soft Rot Pectobacteriaceae species complexes throughout the Durance River catchment from its French Alps sources to its delta
Morris, C. E.; Lacroix, C.; Chandeysson, C.; Guilbaud, C.; Monteil, C.; Piry, S.; Rochelle-Newall, E.; Fiorini, S.; Van Gijsegem, F.; Barny, M.-A.; Berge, O.
10.1101/2022.09.06.506731 — ecology — Posted on 2023-08-01
4554 hadge: a comprehensive pipeline for donor deconvolution in single cell
Curion, F.; Wu, X.; Heumos, L.; Andre, M. G.; Halle, L.; Grant-Peters, M.; Rich-Griffin, C.; Yeung, H.-Y.; Dendrou, C. A.; Schiller, H. B.; Theis, F. J.
10.1101/2023.07.23.550061 — bioinformatics — Posted on 2023-08-01
4556 Loss of PAX6 alters the excitatory/inhibitory neuronal ratio in human cerebral organoids
Chan, W. K.; Negro, D.; Munro, V. M.; Marshall, H. L.; Kozic, Z.; Brown, M.; Beltran, M.; Henderson, N.; Price, D. J.; Mason, J. O.
10.1101/2023.07.31.551262 — developmental biology — Posted on 2023-08-01
4557 Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to study T cell antigen sensitivity by TCRs, CARs, and BiTEs
Patel, A.; Andre, V.; Bustamante Eguiguren, S.; Barton, M. I.; Burton, J.; Denham, E. M.; Pettmann, J.; Morch, A. M.; Kutuzov, M.; Siller-Farfan, J. A.; Dustin, M. L.; van der Merwe, P. A.; Dushek, O.
10.1101/2023.06.15.545075 — immunology — Posted on 2023-08-01
4559 Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease
Duffy, M.; Ding, J.; Langston, R. G.; Shah, S. I.; Nalls, M. A.; Scholz, S. W.; Whitaker, D. T.; Auluck, P. K.; Gibbs, J. R.; Marenco, S.; Cookson, M. R.
10.1101/2023.07.31.551097 — neuroscience — Posted on 2023-08-01