bioRxiv directory

Smith, B.; Feinstein, Y.; Clark, M.; Baltrus, D.

10.1101/537589 — microbiology — Posted on 2019-01-31

3 Protein stability engineering insights revealed by domain-wide comprehensive mutagenesis

Nisthal, A.; Wang, C. Y.; Ary, M. L.; Mayo, S. L.

10.1101/484949 — biochemistry — Posted on 2019-01-31

4 Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks

Hodzic, E.; Shrestha, R.; Zhu, K.; Cheng, K.; Collins, C. C.; Sahinalp, S. C.

10.1101/369850 — systems biology — Posted on 2019-01-31

5 Laboratory Methods Supporting Measles surveillance in Queensland, Australia, 2010-2017

McMahon, J. L.; Northill, J. A.; Finger, M.; Lyon, M.; Lambert, S. B.; Mackay, I. M.

10.1101/472175 — microbiology — Posted on 2019-01-31

6 Species abundance distributions should underpin ordinal cover-abundance transformations

McNellie, M. J.; Dorrough, J.; Oliver, I.

10.1101/535948 — ecology — Posted on 2019-01-31

7 Hydrogen Bond Donors and Acceptors are Generally Depolarized in α-Helices as Revealed by a Molecular Tailoring Approach

Kondo, H. X.; Kusaka, A.; Kitakawa, C. K.; Onari, J.; Yamanaka, S.; Nakamura, H.; Takano, Y.

10.1101/536755 — biophysics — Posted on 2019-01-31

8 Metastable brain waves

Roberts, J. A.; Gollo, L. L.; Abeysuriya, R.; Roberts, G.; Mitchell, P. B.; Woolrich, M. W.; Breakspear, M.

10.1101/347054 — neuroscience — Posted on 2019-01-31

9 KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria.

Hortle, E.; Starrs, L.; Brown, F.; Stephen, J.; Curtis, D.; McMorran, B.; Foote, S.; Burgio, G.

10.1101/186262 — microbiology — Posted on 2019-01-31

10 Effectiveness of Genomic Selection by Response to Selection for Winter Wheat Variety Improvement

Hu, X.; Carver, B.; Powers, C.; Yan, L.; Zhu, L.; Chen, C.

10.1101/537167 — plant biology — Posted on 2019-01-31

11 Y-Family DNA Polymerases Have Three Structural Elements That Promote Accurate dCTP Insertion And Minimize dATP/dGTP/dTTP Misinsertion Opposite a N2-dG Adduct of Benzopyrene

Sholder, G.; Tonzi, P.; Chandani, S.; Loechler, E.

10.1101/536987 — molecular biology — Posted on 2019-01-31

12 Multiple human adipocyte subtypes and mechanisms of their development

Min, S. Y.; Desai, A.; Yang, Z.; Sharma, A.; Genga, R. M. J.; Kucukural, A.; Lifshitz, L.; Maehr, R.; Garber, M.; Corvera, S.

10.1101/537464 — physiology — Posted on 2019-01-31

13 A real-time multiplexed microbial growth intervalometer for capturing high resolution growth curves

Vuono, D.; Lipp, B.; Staub, C.; Loney, E.; Grzymski, J.

10.1101/533356 — microbiology — Posted on 2019-01-31

14 Convergent gain and loss of genomic islands drives lifestyle changes in plant-associated Pseudomonas

Melnyk, R. A.; Hossain, S. S.; Haney, C. H.

10.1101/345488 — microbiology — Posted on 2019-01-31

15 SPDI: Data Model for Variants and Applications at NCBI

Holmes, J. B.; Moyer, E.; Phan, L.; Maglott, D.; Kattman, B. L.

10.1101/537449 — genomics — Posted on 2019-01-31

16 Increasing molar activity by HPLC purification improves 68Ga-DOTA-NAPamide tumor accumulation in a B16/F1 melanoma xenograft model

von Hacht, J. L.; Erdmann, S.; Niederstadt, L.; Prasad, S.; Wagener, A.; Exner, S.; Beindorff, N.; Brenner, W.; Groetzinger, C.

10.1101/537258 — cancer biology — Posted on 2019-01-31

17 Coordinate-based mapping of tabular data enables fast and scalable queries

Piccolo, S. R.; Ence, Z. E.; Hill, K.; Tatlow, P.; Fry, B. J.; Dayton, J. B.

10.1101/536979 — bioinformatics — Posted on 2019-01-31

18 Pyrethroid exposure alters Anopheles albimanus microbiota and resistant mosquitoes harbor more insecticide-metabolizing bacteria

Dada, N.; Lol, J. C.; Benedict, A. C.; Lopez, F.; Sheth, M.; Dzuris, N.; Padilla, N.; Lenhart, A.

10.1101/537480 — microbiology — Posted on 2019-01-31

19 Central spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B

Yu, C.-H.; Redemann, S.; Wu, H.-Y.; Kiewisz, R.; Yoo, T. Y.; Farhadifar, R.; Muller-Reichert, T.; Needleman, D.

10.1101/537290 — cell biology — Posted on 2019-01-31

20 Geometric Sketching Compactly Summarizes the Single-Cell Transcriptomic Landscape

Hie, B.; Cho, H.; DeMeo, B.; Bryson, B.; Berger, B.

10.1101/536730 — bioinformatics — Posted on 2019-01-31

21 Using pan RNA-seq analysis to reveal the ubiquitous existence of 5' and 3' end small RNAs

Xu, X.; Ji, H.; Cheng, Z.; Jin, X.; Yao, X.; Liu, Y.; Zhao, Q.; Zhang, T.; Ruan, J.; Bu, W.; Chen, Z.; Shan, G.

10.1101/444117 — bioinformatics — Posted on 2019-01-31

22 Hypertrophic cardiomyopathy mutations at the folded-back sequestered β-cardiac myosin S1-S2 and S1-S1 interfaces release sequestered heads and increase myosin enzymatic activity

Adhikari, A. S.; Trivedi, D. V.; Sarkar, S. S.; Song, D.; Kooiker, K. B.; Bernstein, D.; Spudich, J. A.; Ruppel, K. M.

10.1101/537159 — biochemistry — Posted on 2019-01-31

23 Sex differences in the neural correlates of age-related episodic memory decline

Subramaniapillai, S.; Rajagopal, S.; Elshiekh, A.; Pasvanis, S.; Ankudowich, E.; Rajah, M. N.

10.1101/535617 — neuroscience — Posted on 2019-01-31

24 A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

Gittens, W.; Johnson, D. J.; Allison, R. M.; Cooper, T. J.; Thomas, H.; Neale, M. J.

10.1101/530667 — molecular biology — Posted on 2019-01-31

25 Spontaneous retrotranspositions in normal tissues are rare and associated with cell-type-specific differentiation

Dong, X.; Zhang, L.; Brazhnik, K.; Lee, M.; Hao, X.; Maslov, A. Y.; Zhang, Z.; Wang, T.; Vijg, J.

10.1101/536896 — genomics — Posted on 2019-01-31

26 The scaling of expansive energy under the Red Queen predicts Cope's Rule

Zliobaite, I.; Fortelius, M.

10.1101/536920 — evolutionary biology — Posted on 2019-01-31

27 Species abundance distributions should underpin ordinal cover-abundance transformations

McNellie, M. J.; Dorrough, J.; Oliver, I.

10.1101/535948 — ecology — Posted on 2019-01-31

28 Low dimensional dynamics for working memory and time encoding

Cueva, C. J.; Marcos, E.; Saez, A.; Genovesio, A.; Jazayeri, M.; Romo, R.; Salzman, C. D.; Shadlen, M. N.; Fusi, S.

10.1101/504936 — neuroscience — Posted on 2019-01-31

29 Impact of population structure in the design of RNA-based diagnostics for antibiotic resistance in Neisseria gonorrhoeae

Wadsworth, C. B.; Sater, M. R. A.; Bhattacharyya, R. P.; Grad, Y. H.

10.1101/537175 — microbiology — Posted on 2019-01-31

30 Increasing Synaptic GluN2B levels within the Basal and Lateral Amygdala Enables the Modification of Strong Reconsolidation Resistant Fear Memories

de Solis, C. A.; Gonzalez, C. U.; Galdamez, M. A.; Perish, J. M.; Woodard, S. W.; Salinas, C. E.; Miller, J. N.; Elahi, H.; Pineda, O. H.; Oad, S.; Gatica de las Fuentes, S.; Owen, M. S.; Sandoval, A.; Holehonnur, R.; Ploski, J. E.

10.1101/537142 — neuroscience — Posted on 2019-01-31

31 BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology

Taga, M.; Petyuk, V. A.; White, C.; Marsh, G.; Ma, Y.; Klein, H.-U.; Connor, S. M.; Khairallah, A.; Olah, M.; Schneider, J.; Ransohoff, R.; Bennett, D. A.; Crotti, A.; Bradshaw, E. M.; De Jager, P. L.

10.1101/535682 — cell biology — Posted on 2019-01-31

32 Hydrogen Bond Donors and Acceptors are Generally Depolarized in α-Helices as Revealed by a Molecular Tailoring Approach

Kondo, H. X.; Kusaka, A.; Kitakawa, C. K.; Onari, J.; Yamanaka, S.; Nakamura, H.; Takano, Y.

10.1101/536755 — biophysics — Posted on 2019-01-31

33 A genome-based species taxonomy of the Lactobacillus Genus Complex

Wittouck, S.; Wuyts, S.; Meehan, C. J.; van Noort, V.; Lebeer, S.

10.1101/537084 — bioinformatics — Posted on 2019-01-31

34 Do damaging variants of SLC6A9, the gene for the glycine transporter 1 (GlyT-1), protect against schizophrenia?

Curtis, D.

10.1101/536904 — genetics — Posted on 2019-01-31

35 Influence of light on particulate organic matter utilization by attached and free-living marine bacteria

Gomez-Consarnau, L.; Needham, D. M.; Weber, P. K.; Fuhrman, J. A.; Mayali, X.

10.1101/537415 — ecology — Posted on 2019-01-31

36 Fetal stage melanopsin (OPN4) and GNAQ (Gαq) signaling regulates vascular development of the eye

Vemaraju, S.; Nayak, G.; Miller, W. E.; Copenhagen, D. R.; Lang, R. A.

10.1101/537225 — developmental biology — Posted on 2019-01-31

37 Chk1 Phosphorylates Cdh1 to Promote SCFβTRCP-Dependent Degradation of Cdh1 During S-Phase

Pal, D.; Torres, A. E.; Messina, A. L.; Dickson, A.; De, K.; Willard, B.; Venere, M.; Summers, M. K.

10.1101/535799 — cell biology — Posted on 2019-01-31

38 A glucose-dependent spatial patterning of exocytosis inhuman β-cells is disrupted in type 2 diabetes

Fu, J.; Githaka, J. M.; Dai, X.; Plummer, G.; Suzuki, K.; Spigelman, A. F.; Bautista, A.; Kim, R.; Greitzer-Antes, D.; Manning Fox, J. E.; Gaisano, H. Y.; MacDonald, P. E.

10.1101/534669 — cell biology — Posted on 2019-01-31

39 Two polybasic domains of septin9 control septin filaments assembly and Golgi integrity

Omrane, M.; Camara, A. S.; Taveneau, C.; Benzoubir, N.; Tubiana, T.; Yu, J.; Guerois, R.; Samuel, D.; Goud, B.; Pous, C.; Bressanelli, S.; Garratt, R. C.; Thiam, A. R.; Gassama-Diagne, A.

10.1101/535039 — cell biology — Posted on 2019-01-31

40 IRE1-UBE2D3 signaling controls the recruitment of myeloid cells to glioblastoma.

Obacz, J.; Archambeau, J.; Le Reste, P. J.; Pineau, R.; Jouan, F.; Barroso, K.; Vlachavas, E.; Voutetakis, K.; Fainsod-Levi, T.; Obiedat, A.; Granot, Z.; Tirosh, B.; Samal, J.; Pandit, A.; Patterson, J.; Zheng, Q.; Negroni, L.; Chatziioannou, A.; Quillien, V.; Avril, T.; chevet, e.

10.1101/533018 — cancer biology — Posted on 2019-01-31

41 Conformational and dynamical plasticity in substrate-binding proteins underlies selective transport in ABC importers

de Boer, M.; Gouridis, G.; Vietrov, R.; Begg, S. L.; Schuurman-Wolters, G. K.; Husada, F.; Eleftheriadis, N.; Poolman, B.; McDevitt, C. A.; Cordes, T.

10.1101/537308 — biophysics — Posted on 2019-01-31

42 A human photoacoustic imaging reporter gene using the clinical dye indocyanine green.

Nystrom, N. N.; Yip, L. C.; Carson, J. J.; Scholl, T. J.; Ronald, J. A.

10.1101/537100 — bioengineering — Posted on 2019-01-31

43 Semi-synthetic Cinnamodial Analogues: Structural Insights into the Insecticidal and Antifeedant Activities of Drimane Sesquiterpenes Against the Mosquito Aedes aegypti

Manwill, P.; Kalsi, M.; Wu, S.; Cheng, X.; Piermarini, P.; Rakotondraibe, H. L.

10.1101/536961 — pharmacology and toxicology — Posted on 2019-01-31

44 Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven AAVs

Graybuck, L. T.; Sedeno-Cortes, A.; Nguyen, T. N.; Walker, M.; Szelenyi, E.; Lenz, G.; Sieverts, L.; Kim, T. K.; Garren, E.; Kalmbach, B.; Yao, S.; Mortrud, M.; Mich, J.; Goldy, J.; Smith, K. A.; Dee, N.; Yao, Z.; Cetin, A.; Levi, B. P.; Lein, E.; Ting, J.; Zeng, H.; Daigle, T.; Tasic, B.

10.1101/525014 — neuroscience — Posted on 2019-01-31

45 Free water in white matter differentiates MCI and AD from control subjects

Dumont, M.; Roy, M.; Jodoin, P.-M.; Morency, F. C.; Houde, J.-C.; Xie, Z.; Bauer, C.; Samad, T. A.; Van Dijk, K. R. A.; Goodman, J.; Descoteaux, M.

10.1101/537092 — neuroscience — Posted on 2019-01-31

46 The development of spatiotemporal organization of episodic memory in children and its disruption in Williams Syndrome

Mastrogiuseppe, M.; Bertelsen, N.; Bedeschi, M. F.; Lee, S. A.

10.1101/534743 — neuroscience — Posted on 2019-01-31

47 The genomic architecture of competitive response of Arabidopsis thaliana is highly flexible between monospecific and plurispecific neighborhoods.

Libourel, C.; Baron, E.; Lenglet, J.; Amsellem, L.; Roby, D.; Fabrice, R.

10.1101/536953 — genetics — Posted on 2019-01-31

48 DeePaC: Predicting pathogenic potential of novel DNA with a universal framework for reverse-complement neural networks

Bartoszewicz, J. M.; Seidel, A.; Rentzsch, R.; Renard, B. Y.

10.1101/535286 — bioinformatics — Posted on 2019-01-31

49 Leveraging breeding values obtained from random regression models for genetic inference of longitudinal traits

Campbell, M. T.; Momen, M.; Walia, H.; Morota, G.

10.1101/435685 — genetics — Posted on 2019-01-31

50 Sulcal organization in the medial frontal cortex reveals insights into primate brain evolution

AMIEZ, C.; Sallet, J.; Hopkins, W. D.; Meguerditchian, A.; Hadj-Bouziane, F.; BenHamed, S.; Wilson, C. R. E.; Procyk, E.; Petrides, M.

10.1101/527374 — neuroscience — Posted on 2019-01-31

51 The idiosyncratic drivers of correlated evolution

Dench, J.; Hinz, A.; Aris-Brosou, S.; Kassen, R.

10.1101/474536 — evolutionary biology — Posted on 2019-01-31

52 Computational modeling of anthocyanin pathway evolution: Biases, hotspots, and trade-offs

Wheeler, L. C.; Smith, S. D.

10.1101/511089 — evolutionary biology — Posted on 2019-01-31

53 The effect of ocean warming on black sea bass (Centropristis striata) aerobic scope and hypoxia tolerance

Slesinger, E.; Andres, A.; Young, R.; Seibel, B.; Saba, V.; Phelan, B.; Rosendale, J.; Wieczorek, D.; Saba, G.

10.1101/507368 — physiology — Posted on 2019-01-31

54 A fast and general method to empirically estimate the complexity of brain responses to transcranial and intracranial stimulations

Comolatti, R.; Pigorini, A.; Casarotto, S.; Fecchio, M.; Faria, G.; Sarasso, S.; Rosanova, M.; Gosseries, O.; Boly, M.; Bodart, O.; Ledoux, D.; Brichant, J.-F.; Nobili, L.; Laureys, S.; Tononi, G.; Massimini, M.; Casali, A. G.

10.1101/445882 — neuroscience — Posted on 2019-01-31

55 Explore or reset? Pupil diameter transiently increases in self-chosen switches between cognitive labor and leisure in either direction

Algermissen, J.; Bijleveld, E.; Jostmann, N. B.; Holland, R. W.

10.1101/379214 — neuroscience — Posted on 2019-01-31

56 DART-ID increases single-cell proteome coverage

Chen, A. T.; Franks, A.; Slavov, N.

10.1101/399121 — bioinformatics — Posted on 2019-01-31

57 scID: Identification of equivalent transcriptional cell populations across single cell RNA-seq data using discriminant analysis

Boufea, K.; Seth, S.; Batada, N. N.

10.1101/470203 — bioinformatics — Posted on 2019-01-31

58 An efficient and robust laboratory workflow and tetrapod database for larger scale eDNA studies

Axtner, J.; Crampton-Platt, A.; Hoerig, L. A.; Mohamed, A.; Xu, C. C. Y.; Yu, D. W.; Wilting, A.

10.1101/345082 — molecular biology — Posted on 2019-01-31

59 The phylogenetically distinct early human embryo

Singh, M.; Widmann, T. J.; Bansal, V.; Cortes, J. L.; Schumann, G. G.; Wunderlich, S.; Martin, U.; Garcia-Perez, J. L.; Hurst, L. D.; Izsvak, Z.

10.1101/318329 — developmental biology — Posted on 2019-01-31

60 Male clients of male sex workers in West Africa: A neglected high risk population

KOUNTA, C. H.; Sagaon-Teyssier, L.; Coulaud, P.-J.; Mora, M.; Maradan, G.; Bourrelly, M.; keita, A. A.; Yoro, S. A. B.; Anoma, C.; Coulibaly, C.; Dah, E. T. T.; Agbomadji, S.; Mensah, E.; Bernier, A.; Couderc, C.; Dembele Keita, B.; Laurent, C.; Spire, B.

10.1101/536482 — epidemiology — Posted on 2019-01-31

61 Cortical tracking of speech reveals top-down reconstructive processes

Mukherjee, S.; Tomassini, A.; Badino, L.; Pastore, A.; Fadiga, L.; D'Ausilio, A.

10.1101/536946 — neuroscience — Posted on 2019-01-31

62 Addressing reverse inference in structural brain alterations

Cauda, F.; Nani, A.; Liloia, D.; Manuello, J.; Premi, E.; Duca, S.; Fox, P.; Costa, T.

10.1101/536847 — neuroscience — Posted on 2019-01-31

63 Information recovery following a retrospective cue decreases with time.

Nouri, A.; Ester, E.

10.1101/537076 — neuroscience — Posted on 2019-01-31

64 Insights into the mysterious genetic variation profile of tprK inTreponema pallidum under the development of natural human syphilis infection

Liu, D.; Tong, M.-L.; Lin, Y.; Liu, L.-L.; Lin, L.-R.; Yang, T.-C.

10.1101/536573 — microbiology — Posted on 2019-01-31

65 Comparative genome analysis indicates rapid evolution of pathogenicity genes in Colletotrichum tanaceti

Lelwala, R. V.; Korhonen, P. K.; Young, N. D.; Scott, J. B.; Ades, P. K.; Gasser, R. B.; Taylor, P. W. J.

10.1101/536516 — genomics — Posted on 2019-01-31

66 Multilevel regulation of the glass locus during Drosophila eye development

Fritsch, C.; Bernardo-Garcia, F. J.; Humberg, T.; Miellet, S.; Almeida, S.; Huber, A.; Sprecher, S.

10.1101/537118 — developmental biology — Posted on 2019-01-31

67 Molecular Dynamics simulations of Alzheimer's variants, R47H and R62H, in TREM2 provide evidence for structural alterations behind functional changes

Menzies, G. E.; Sims, R.; Williams, J.

10.1101/536540 — systems biology — Posted on 2019-01-31

68 Label-free Method for Classification of T cell Activation

Walsh, A.; Mueller, K.; Jones, I.; Walsh, C. M.; Piscopo, N.; Niemi, N. N.; Pagliarini, D. J.; Saha, K.; Skala, M. C.

10.1101/536813 — bioengineering — Posted on 2019-01-31

69 Protein Condensates with Appropriate Material Properties Regulate Tumorigenesis

Li, W.; Hu, J.; Shi, B.; Jiang, H.

10.1101/536839 — biochemistry — Posted on 2019-01-31

70 Curriculum-based outdoor learning for children aged 9-11: A qualitative analysis of pupils' and teachers' views.

Marchant, E.; Todd, C.; Cooksey, R.; Dredge, S.; Jones, H.; Reynolds, D.; Stratton, G.; Dwyer, R.; Lyons, R.; Brophy, S.

10.1101/536441 — scientific communication and education — Posted on 2019-01-31

71 Cooperative population coding facilitates efficient sound source separability by adaptation to spatial statistics

Gleiss, H.; Encke, J.; Lingner, A.; Jennings, T. R.; Brosel, S.; Kunz, L.; Grothe, B.; Pecka, M.

10.1101/536524 — neuroscience — Posted on 2019-01-31

72 The nature of the perceptual representation for decision making

Yeon, J.; Rahnev, D.

10.1101/537068 — neuroscience — Posted on 2019-01-31

73 Escherichia coli O157:H7 responds to phosphate starvation by modifying LPS involved in biofilm formation

Vogeleer, P.; Vincent, A. T.; Chekabab, S. M.; Charette, S. J.; Novikov, A.; Caroff, M.; Beaudry, F.; Jacques, M.; Harel, J.

10.1101/536201 — microbiology — Posted on 2019-01-31

74 Mapping the lineage relationship between CXCR5+ and CXCR5- CD4+ T cells in HIV infected human lymph nodes

del Alcazar, D.; Wang, Y.; He, C.; Wendel, B. S.; Del Rio-Estrada, P. M.; Lin, J.; Ablanedo-Terrazas, Y.; Malone, M. J.; Hernande, S. M.; Frank, I.; Naji, A.; Reyes-Teran, G.; Jiang, N.; Su, L. F.

10.1101/537050 — immunology — Posted on 2019-01-31

75 Bayesian Active Learning for Optimization and Uncertainty Quantification in Protein Docking

Cao, Y.; Shen, Y.

10.1101/537035 — bioinformatics — Posted on 2019-01-31

76 Sex differences in the effects of gonadal hormones on white matter microstructure development in adolescence

Ho, T. C.; Oskirko, K.; Colich, N. L.; Sisk, L.; Gotlib, I.

10.1101/536003 — neuroscience — Posted on 2019-01-31

77 Cortical and subcortical T1 white/gray contrast, chronological age, and cognitive performance

Lewis, J. D.; Fonov, V. S.; Collins, D. L.; Evans, A. C.; Tohka, J.

10.1101/537043 — neuroscience — Posted on 2019-01-31

78 Regulation of CHD2 expression by the Chaserr long noncoding RNA is essential for viability

Rom, A.; Melamed, L.; Goldrich, M. J.; Kadir, R.; Golan, M.; Biton, I.; Ben-Tov Perry, R.; Ulitsky, I.

10.1101/536771 — molecular biology — Posted on 2019-01-31

79 Evolutionary dynamics of neoantigens in growing tumours

Lakatos, E.; Williams, M. J.; Schenck, R. O.; Cross, W. C. H.; Househam, J.; Werner, B.; Gatenbee, C.; Robertson-Tessi, M.; Barnes, C. P.; Anderson, A. R. A.; Sottoriva, A.; Graham, T. A.

10.1101/536433 — cancer biology — Posted on 2019-01-31

80 Prey capturing and feeding apparatus of dragonfly nymph

Kundanati, L.; Das, P.; Pugno, N. M.

10.1101/536805 — bioengineering — Posted on 2019-01-31

81 The Arabidopsis thaliana pan-NLRome

Van de Weyer, A.-L.; Monteiro, F.; Furzer, O. J.; Nishimura, M. T.; Cevik, V.; Witek, K.; Jones, J. D. G.; Dangl, J. L.; Weigel, D.; Bemm, F.

10.1101/537001 — plant biology — Posted on 2019-01-31

82 Horizontal transmission of the entomopathogenic fungal isolate INRS-242 of Beauveria bassiana in emerald ash borer, Agrilus planipennis Fairmaire

Srei, N.; Lavallee, R.; Guertin, C.

10.1101/532838 — microbiology — Posted on 2019-01-31

83 A Polygenic Score for Body Mass Index is Associated with Depressive Symptoms via Early Life Stress: Evidence for Gene-Environment Correlation

Avinun, R.; Hariri, A. R.

10.1101/536938 — genetics — Posted on 2019-01-31

84 Environmental Niche Adaptation Revealed Through Fine Scale Phenological Niche Modeling

Van Dam, M. H.; Rominger, A. J.; Brewer, M. S.

10.1101/534636 — evolutionary biology — Posted on 2019-01-31

85 Adaptations of Atribacteria to life in methane hydrates: hot traits for cold life

Glass, J. B.; Ranjan, P.; Kretz, C. B.; Nunn, B. L.; Johnson, A. M.; McManus, J.; Stewart, F. J.

10.1101/536078 — microbiology — Posted on 2019-01-31

86 Mouse Norovirus infection arrests host cell translation uncoupled from the stress granule-PKR-eIF2α axis

Fritzlar, S.; Aktepe, T.; Chao, Y.-W.; McAllaster, M.; Wilen, C.; White, P.; Mackenzie, J.

10.1101/536052 — microbiology — Posted on 2019-01-31

87 Water quality assessments and metagenomic analysis of the polluted river Apatlaco, Mexico

Breton-Deval, L.; Juarez, k.; Sanchez-Flores, A.; Vera-Estrella, R.

10.1101/536128 — ecology — Posted on 2019-01-31

88 Formulas for Determining the Recovery Times for Optimal Two-Point Saturation-Recovery Measurement of the MR Longitudinal Relaxation Rate

Hsu, J.-J.

10.1101/534891 — bioengineering — Posted on 2019-01-31

89 Testing the exteroceptive function of nociception: the role of visual experience in shaping the spatial representations of nociceptive inputs.

Vanderclausen, C.; Bourgois, M.; De Volder, A.; Legrain, V.

10.1101/536367 — neuroscience — Posted on 2019-01-31

90 Disease and phenotype relevant genetic variants identified from histone acetylomes in human hearts

Lek Wen, T. W.; Anene, G.; Wong, E.; Tan, H. S.; Pan, B.; Lee, M.; Autio, M.; Morley, M.; Margulies, K.; Cappola, T.; Loh, M.; Chambers, J.; Prabhakar, S.; Foo, R.

10.1101/536763 — genomics — Posted on 2019-01-31

91 Molecular dating for phylogenies containing a mix of populations and species

Mello, B.; Tao, Q.; Kumar, S.

10.1101/536656 — ecology — Posted on 2019-01-31

92 Phase dependence of response curves to stimulation and their relationship: from a Wilson-Cowan model to essential tremor patient data

Duchet, B.; Weerasinghe, G.; Cagnan, H.; Brown, P.; Bick, C.; Bogacz, R.

10.1101/535880 — neuroscience — Posted on 2019-01-31

93 High-throughput task to study memory recall during spatial navigation in rodents

Morales, L.; Tomas, D. P.; Dalmau, J.; de la Rocha, J.; Jercog, P. E.

10.1101/534313 — neuroscience — Posted on 2019-01-31

94 Hemocyte subpopulation changes in Bithynia snails infected with Opisthorchis viverrini in Thailand.

Suwannatrai, K.; Thinkhamrop Suwannatrai, A. T.; Donthaisong, C.; Arunsan, P.; Thinkhamrop, K.; Tabsripair, P.; Welbat, J. U.; Tangkawattana, S.; Sotillo, J.; Tesana, S.

10.1101/536292 — immunology — Posted on 2019-01-31

95 Geometric Sketching Compactly Summarizes the Single-Cell Transcriptomic Landscape

Hie, B.; Cho, H.; DeMeo, B.; Bryson, B.; Berger, B.

10.1101/536730 — bioinformatics — Posted on 2019-01-31

96 Multi-omics profiling of CHO parental hosts reveals cell line-specific variations in bioprocessing traits

Lakshmanan, M.; Kok, Y. J.; Lee, A. P.; Kyriakopoulos, S.; Lim, H. L.; Teo, G.; Poh, S. L.; Tang, W. Q.; Hong, J.; Tan, A. H.-M.; Bi, X.; Ho, Y. S.; Zhang, P.; Ng, S. K.; Lee, D.-Y.

10.1101/532150 — systems biology — Posted on 2019-01-31

97 Highly efficient genome editing in primary bronchial epithelial cells establishes FOXJ1 as essential for ciliation in human airways

Rapiteanu, R.; Karagyozova, T.; Zimmermann, N.; Wayne, G.; Martufi, M.; Belyaev, N. N.; Singh, K.; Betts, J.; Beinke, S.; Maratou, K.

10.1101/533869 — molecular biology — Posted on 2019-01-31

98 Tissue shape determines actin-dependent nuclear migration mechanisms in neuroepithelia

Yanakieva, I.; Erzberger, A.; Matejcic, M.; Modes, C. D.; Norden, C.

10.1101/536698 — cell biology — Posted on 2019-01-31

99 Hydrogen Bond Donors and Acceptors are Generally Depolarizedin α-Helices as Revealed by a Molecular Tailoring Approach

Kondo, H. X. X.; Kusaka, A.; Kitakawa, C. K.; Onari, J.; Yamanaka, S.; Nakamura, H.; Takano, Y.

10.1101/536755 — biophysics — Posted on 2019-01-31

100 Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/Calmodulin-dependent protein kinase II

McSpadden, E. D.; Xia, Z.; Chi, C. C.; Susa, A. C.; Shah, N. H.; Gee, C. L.; Williams, E. R.; Kuriyan, J.

10.1101/536094 — biochemistry — Posted on 2019-01-31

101 Re-curation and Rational Enrichment of Knowledge Graphs in Biological Expression Language

Hoyt, C.; Domingo-Fernandez, D.; Aldisi, R.; Xu, L.; Kolpeja, K.; Spalek, S.; Wollert, E.; Bachman, J.; Gyori, B.; Greene, P.; Hofmann-Apitius, M.

10.1101/536409 — systems biology — Posted on 2019-01-31

102 PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury

Southern, W. M.; Nichenko, A. S.; Tehrani, K. F.; McGranahan, M. J.; Krishnan, L.; Qualls, A. E.; Jenkins, N. J.; Mortensen, L. J.; Yin, H.; Yin, A.; Guldberg, R. E.; Greising, S. M.; Call, J. A.

10.1101/535328 — physiology — Posted on 2019-01-31

103 Retrovirus insertion site analysis of LGL leukemia patient genomes

Li, W.; Yang, L.; Harris, R. S.; Lin, L.; Olson, T. L.; Hamele, C. E.; Feith, D. J.; Loughran, T. P.; Poss, M.

10.1101/535997 — genomics — Posted on 2019-01-31

104 Whole genome sequencing and comparative genomic analysis reveal novel allelic variations unique to a purple colored rice landrace (Oryza sativa ssp. indica cv. Purpleputtu)

Lachagari, V. B. R.; Gupta, R.; Lekkala, S. P.; Mahadevan, L.; Kuriakose, B.; Chakravartty, N.; Katta, A. V. S. K. M.; Santhosh, S.; Reddy, A. R.; Thomas, G.

10.1101/536326 — genomics — Posted on 2019-01-31

105 Silver-spoon upbringing improves early-life fitness but promotes reproductive ageing in a wild bird

Spagopoulou, F.; Teplitsky, C.; Lind, M. I.; Gustafsson, L.; Maklakov, A.

10.1101/535625 — evolutionary biology — Posted on 2019-01-31

106 TEX-FBA: A constraint-based method for integrating gene expression, thermodynamics, and metabolomics data into genome-scale metabolic models

Pandey, V.; Hernandez Gardiol, D.; Chiappino Pepe, A.; Hatzimanikatis, V.

10.1101/536235 — systems biology — Posted on 2019-01-31

107 Turning a green alga red: engineering astaxanthin biosynthesis by intragenic pseudogene revival in Chlamydomonas reinhardtii.

Perozeni, F.; Cazzaniga, S.; Baier, T.; Zanoni, F.; Zoccatelli, G.; Lauersen, K. J.; Wobbe, L.; Ballottari, M.

10.1101/535989 — plant biology — Posted on 2019-01-31

108 The network underlying human higher-order motor control: Insights from machine learning-based lesion-behaviour mapping in apraxia

Sperber, C.; Wiesen, D.; Goldenberg, G.; Karnath, H.-O.

10.1101/536391 — neuroscience — Posted on 2019-01-31

109 Extrachromosomal circular DNA, microDNA, without canonical promoters produce short regulatory RNAs that suppress gene expression

Paulsen, T.; Shibata, Y.; Kumar, P.; Dillon, L.; Dutta, A.

10.1101/535831 — molecular biology — Posted on 2019-01-31

110 Characterization of Sex Differences in Ocular HSV-1 Infection and Herpes Stromal Keratitis Pathogenesis of Wild Type and Herpesvirus Entry Mediator Knockout Mice

Riccio, R. E.; Park, S. J.; Longnecker, R.; Kopp, S. J.

10.1101/536185 — microbiology — Posted on 2019-01-31

111 Geographic Patterns of Bacterioplankton among Lakes of the Middle and Lower Reaches of the Yangtze River Basin, China

Bai, C.; Cai, J.; Zhou, L.; Jiang, X.; Hu, Y.; Dai, J.; Shao, K.; Tang, X.; Yang, X.; Gao, G.

10.1101/536219 — microbiology — Posted on 2019-01-31

112 Non-Invasive Detection of Viral Antibodies Using Oral Flocked Swabs

Speicher, D. J.; Luinstra, K.; Smith, E. J.; Castriciano, S.; Smieja, M.

10.1101/536227 — microbiology — Posted on 2019-01-31

113 The enigmatic role of fungal annexins: the case of Cryptococcus neoformans

Maryam, M.; Fu, M. S.; Alanio, A.; Camacho, E.; Diego, G.; Faneuff, E. E.; Grossman, N. T.; Casadevall, A.; Coelho, C.

10.1101/536193 — microbiology — Posted on 2019-01-31

114 Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

Zhang, L.; Dong, X.; Lee, M.; Maslov, A. Y.; Wang, T.; Vijg, J.

10.1101/535906 — genomics — Posted on 2019-01-31

115 Imprinted gene expression at the Dlk1-Dio3 cluster is controlled by both maternal and paternal IG-DMRs in a tissue-specific fashion.

Alexander, K. A.; Garcia-Garcia, M. J.

10.1101/536102 — genetics — Posted on 2019-01-31

116 Variation in space and time: a long-term examination of density-dependent dispersal in a woodland rodent

Denomme-Brown, S. T.; Cottenie, K.; Falls, J. B.; Falls, E. A.; Brooks, R. J.; McAdam, A. G.

10.1101/536144 — ecology — Posted on 2019-01-31

117 DnaJB6 is a RanGTPdependent microtubule Organization during mitosis

Rosas-Salvans, M.; Vernos, I.

10.1101/536045 — cell biology — Posted on 2019-01-31

118 Towards creating an extended metabolic model (EMM) for E. coli using enzyme promiscuity prediction and metabolomics data

Amin, S. A.; Chavez, E.; Nair, N. U.; Hassoun, S.

10.1101/536060 — systems biology — Posted on 2019-01-31

119 DypFISH: Dynamic Patterned FISH to Interrogate RNA and Protein Spatial and Temporal Subcellular Distribution

Savulescu, A. F.; Brackin, R.; Bouilhol, E.; Dartigues, B.; Warrell, J. H.; Pimentel, M. R.; Dallongeville, S.; Schmoranzer, J.; Olivo-Marin, J.-C.; Gomes, E. R.; Nikolski, M.; Mhlanga, M. M.

10.1101/536383 — systems biology — Posted on 2019-01-31

120 Suppressed Osteocyte Perilacunar / Canalicular RemodelingPlays a Causal Role in Osteoarthritis

Mazur, C. M.; Woo, J. J.; Yee, C. S.; Fields, A. J.; Acevedo, C.; Bailey, K. N.; Fowler, T. W.; Lotz, J. C.; Dang, A.; Kuo, A.; Vail, T. P.; Alliston, T.

10.1101/534768 — physiology — Posted on 2019-01-31

121 Bright near-infrared genetically encoded voltage indicator for all-optical electrophysiology

Monakhov, M.; Matlashov, M.; Colavita, M.; Song, C.; SHCHERBAKOVA, D. M.; ANTIC, S. D.; Verkhusha, V.; Knopfel, T.

10.1101/536359 — neuroscience — Posted on 2019-01-31

122 mTOR suppresses macroautophagy during postnatal development of the striatum.

Lieberman, O.; Pigulevskiy, I.; Post, M.; Sulzer, D.; Santini, E.

10.1101/536680 — neuroscience — Posted on 2019-01-31

123 Prophylactic TLR9 stimulation reduces brain metastasis through microglia activation

Benbenishty, A.; Gadrich, M.; Cottarelli, A.; Lubart, A.; Kain, D.; Amer, M.; Shaashua, L.; Glasner, A.; Erez, N.; Agalliu, D.; Mayo, L.; Ben-Eliyahu, S.; Blinder, P.

10.1101/533927 — neuroscience — Posted on 2019-01-31

124 Acute ethanol intoxication induces preferred loss of presynaptic boutons devoid of mitochondria in vivo

Protzmann, J.; Jaiswal, A.; Rohr, K.; Kuner, T.; Cambridge, S.; Knabbe, J.

10.1101/536334 — neuroscience — Posted on 2019-01-31

125 Ensuring meiotic DNA break formation in the mouse pseudoautosomal region

Acquaviva, L.; Boekhout, M.; Karasu, M. E.; Brick, K.; Pratto, F.; van Overbeek, M.; Kauppi, L.; Camerini-Otero, R. D.; Jasin, M.; Keeney, S.

10.1101/536136 — molecular biology — Posted on 2019-01-31

126 Coarse-grain simulations on NMR conformational ensembles highlight non catalytic functional residues in proteins

Sacquin-Mora, S.

10.1101/532507 — molecular biology — Posted on 2019-01-31

127 Identification of a Type IV CRISPR-Cas system located exclusively on IncHI1B/ IncFIB plasmids in Enterobacteriaceae

Newire, E.; Aydin, A.; Juma, S.; Enne, V.; Roberts, A.

10.1101/536375 — microbiology — Posted on 2019-01-31

128 HBEGF+ macrophages identified in rheumatoid arthritis promote joint tissue invasiveness and are reshaped differentially by medications

Kuo, D.; Ding, J.; Cohn, I.; Zhang, F.; Wei, K.; Rao, D.; Rozo, C.; Sokhi, U. K.; Accelerating Medicines Partnership RA/SLE Network, ; DiCarlo, E. F.; Brenner, M. B.; Bykerk, V. P.; Goodman, S. M.; Raychaudhuri, S.; Rätsch, G.; Ivashkiv, L. B.; Donlin, L. T.

10.1101/525758 — immunology — Posted on 2019-01-31

129 Genotype-phenotype relationships in children with copy number variants associated with high neuropsychiatric risk: Findings from the Intellectual Disability & Mental Health: Assessing the Genomic Impact on Neurodevelopment (IMAGINE-ID) study

Chawner, S.; Owen, M.; Holmans, P.; Raymond, L.; Skuse, D.; Hall, J.; van den Bree, M.; IMAGINE-ID Consortium,

10.1101/535708 — genomics — Posted on 2019-01-31

130 A novel mesocosm set-up reveals strong methane emission reduction in submerged peat moss Sphagnum cuspidatum by tightly associated methanotrophs.

Kox, M. A. R.; Smolders, A. J. P.; Speth, D. R.; Lamers, L. P. M.; Op den Camp, H. J. M.; Jetten, M. S. M.; Van Kessel, M. A. H. J.

10.1101/536268 — ecology — Posted on 2019-01-31

131 Neuronal differentiation affects tissue mechanics and progenitor arrangement in the vertebrate neuroepithelium

Guerrero, P.; Perez-Carrasco, R.; Zagorski, M.; Page, D.; Kicheva, A.; Briscoe, J.; Page, K.

10.1101/536342 — developmental biology — Posted on 2019-01-31

132 Chk1 Phosphorylates Cdh1 to Promote SCFβTRCP-Dependent Degradation of Cdh1 During S-Phase

Pal, D.; Torres, A. E.; Messina, A. L.; Dickson, A.; De, K.; Willard, B.; Venere, M.; Summers, M. K.

10.1101/535799 — cell biology — Posted on 2019-01-31

133 Mutational analysis of field cancerization in bladder cancer

Strandgaard, T.; Nordentoft, I.; Lamy, P.; Christensen, E.; Borg Houlberg Thomsen, M.; Bjerggaard Jensen, J.; Dyrskjot, L.

10.1101/536466 — cancer biology — Posted on 2019-01-31

134 Comparative analyses of metabolic pathways in mycobacteria: Insights into the identification and characterisation of new drug targets in M. tuberculosis, M. leprae and M. abscessus

Bannerman, B. P.; Vedithi, S. C.; Julvez, J.; Torres, P.; Waman, V. P.; Munir, A.; Mendes, V.; Malhotra, S.; Skwark, M. J.; Oliver, S. G.; Blundell, T. L.

10.1101/535856 — bioinformatics — Posted on 2019-01-31

135 Genome-Scale reconstruction of Paenarthrobacter aurescens TC1 metabolic model towards the study of atrazine bioremediation

Ofaim, S.; Zarecki, R.; Porob, S.; Gat, D.; Lahav, T.; Xu, X.; Kashi, Y.; Aly, R.; Jiandong, J.; Eizenberg, H.; Ronen, Z.; Freilich, S.

10.1101/536011 — bioinformatics — Posted on 2019-01-31

136 SCCNV: a software tool for identifying copy number variation from single-cell whole-genome sequencing

Dong, X.; Zhang, L.; Hao, X.; Wang, T.; Vijg, J.

10.1101/535807 — bioinformatics — Posted on 2019-01-31

137 DeePaC: Predicting pathogenic potential of novel DNA with a universal framework for reverse-complement neural networks

Bartoszewicz, J. M.; Seidel, A.; Rentzsch, R.; Renard, B. Y.

10.1101/535286 — bioinformatics — Posted on 2019-01-31

138 Visual interference can help and hinder memory: Measuring memory fidelity using a novel circular shape space

Li, A. Y.; Liang, J.; Lee, A. C. H.; Barense, M. D.

10.1101/535922 — neuroscience — Posted on 2019-01-31

139 Global proteomic profiling of primary macrophages during M. tuberculosis infection identifies TAX1BP1 as a mediator of autophagy targeting

Budzik, J. M.; Garelis, N. E.; Repasy, T.; Roberts, A. W.; Popov, L.; Parry, T. J.; Jiminez-Morales, D.; Swaney, D.; Johnson, J. R.; Krogan, N. J.; Cox, J. S.

10.1101/534917 — microbiology — Posted on 2019-01-31

140 Focused natural product elucidation by prioritizing high-throughput metabolomic studies with machine learning

Tobias, N.; Parra-Rojas, C.; Shi, Y.-N.; Shi, Y.-M.; Simonyi, S.; Thanwisai, A.; Vitta, A.; Chantratita, N.; Hernandez-Vargas, E. A.; Bode, H. B.

10.1101/535781 — microbiology — Posted on 2019-01-31

141 Transcranial photobiomodulation with infrared laser increases power of brain oscillations

Wang, X.; Dmochowski, J.; Zeng, L.; Kallioniemi, E.; Husain, M.; Gonzalez-Lima, F.; Liu, H.

10.1101/535757 — bioengineering — Posted on 2019-01-31

142 Network analysis to evaluate the impact of research funding on research community consolidation

Hicks, D. J.; Coil, D. A.; Stahmer, C. G.; Eisen, J. A.

10.1101/534495 — scientific communication and education — Posted on 2019-01-31

143 Transgeneratonal inheritance of ethanol preference is caused by maternal NPF repression

Bozler, J.; Kacsoh, B. Z.; Bosco, G.

10.1101/536599 — molecular biology — Posted on 2019-01-31

144 Species abundance distributions should underpin ordinal cover-abundance transformations

McNellie, M. J.; Dorrough, J.; Oliver, I.

10.1101/535948 — ecology — Posted on 2019-01-31

145 Doc2b Ca2+-binding site mutants act as a gain of function at rest and loss of function during neuronal activity

Bourgeois-Jaarsma, Q.; Verhage, M.; Groffen, A. J.

10.1101/536581 — cell biology — Posted on 2019-01-31

146 Fourier ring correlation simplifies image restoration in fluorescence microscopy

Koho, S. V.; Tortarolo, G.; Castello, M.; Deguchi, T.; Diaspro, A.; Vicidomini, G.

10.1101/535583 — bioinformatics — Posted on 2019-01-31

147 Comparison of expression profiling through microarray and RNA-seq analysis for Nipah virus

Rajput, A.; Kumar, M.

10.1101/536284 — bioinformatics — Posted on 2019-01-31

148 A 7-channel high-Tc SQUID-based on-scalp MEG system

Pfeiffer, C.; Ruffieux, S.; Jönsson, L.; Chukharkin, M. L.; Kalaboukhov, A.; Xie, M.; Winkler, D.; Schneiderman, J. F.

10.1101/534107 — neuroscience — Posted on 2019-01-31

149 Human Myosin 1e tail but not motor domain replaces fission yeast Myo1 domains to support myosin-I function during endocytosis

Barger, S. R.; James, M. L.; Pellenz, C. D.; Krendel, M.; Sirotkin, V.

10.1101/535765 — cell biology — Posted on 2019-01-31

150 The Role of Orexin-1 Receptor Signaling in Demand for the Opioid Fentanyl

Fragale, J. E.; Pantazis, C. B.; James, M. H.; Aston-Jones, G.

10.1101/533059 — animal behavior and cognition — Posted on 2019-01-31

151 Microcolonies: a novel morphological form of pathogenic Mycoplasma spp

Rakovskaya, I. V.; Ermolaeva, S. A.; Levina, G. A.; Barkhatova, O. I.; Mukhachev, A. Y.; Andrievskaya, S. G.; Zhukhovitsky, V. G.; Gorina, L. G.; Miller, G. G.; Sysolyatina, E. V.

10.1101/535559 — microbiology — Posted on 2019-01-31

152 \"Low-cost\" initial burst of root development in whole Fagus crenata seedlings: The key to survival?

Kurosawa, Y.; Mori, S.; Wang, M.; Ferrio, J. P.; Yamaji, K.; Yoshimura, K.; Qur'ani, C. G.

10.1101/535500 — plant biology — Posted on 2019-01-31

153 Hepatotoxicity during 6-thioguanine treatment in inflammatory bowel disease and childhood acute lymphoblastic leukaemia: a systematic review

Toksvang, L. N.; Schmiegelow, K.; Schmidt, M. S.; Arup, S.; Larsen, R. H.; Frandsen, T. L.; Rank, C. U.

10.1101/535518 — pharmacology and toxicology — Posted on 2019-01-31

154 Implication of HisF from Acinetobacter baumannii in persistence during a pneumonia infection

Martinez-Guitian, M.; Vazquez-Ucha, J. C.; Alvarez-Fraga, L.; Conde-Perez, K.; Vallejo, J. A.; Bou, G.; Poza, M.; Beceiro, A.

10.1101/534966 — microbiology — Posted on 2019-01-31

155 Higher seroprevalence of Entamoeba histolytica than that of HIV-1 at a voluntary counselling and testing centre in Tokyo

Yanagawa, Y.; Nagashima, M.; Gatanaga, H.; Kikuchi, Y.; Oka, S.; Yokoyama, K.; Shinkai, T.; Sadamasu, K.; Watanabe, K.

10.1101/536565 — microbiology — Posted on 2019-01-31

156 Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes

Shafquat, A.; Crystal, R. G.; Mezey, J.

10.1101/536532 — genetics — Posted on 2019-01-31

157 Cases of Cutaneous Leishmaniasis in a peri-urban settlement in Kenya, 2016

Ngere, I. A.; Boru, W.; Isack, A.; Muiruri, J.; Obonyo, M.; Matendechero, S.; Gura, Z.

10.1101/536557 — epidemiology — Posted on 2019-01-31

158 Temperament profile and its association with the vulnerability to smartphone addiction of medical students in Indonesia

Hanafi, E.; Siste, K.; Wiguna, T.; Kusumadewi, I.; Nasrun, M. W.

10.1101/536474 — scientific communication and education — Posted on 2019-01-31

159 The synergistic antitumor effect of combined Anti-Human Epidermal Growth Factor Receptor 2 (HER2) antibody and Gamma Interferon therapy to Ab resistant breast cancer cells

Gocho, T.; Tsuchiya, H.

10.1101/536490 — cancer biology — Posted on 2019-01-31

160 Dual pathway for metabolic engineering of E. coli metabolism to produce the highly valuable hydroxytyrosol

Trantas, E.; Navakoudis, E.; Pavlidis, T.; Nikou, T.; Halabalaki, M.; Skaltsounis, L.; Ververidis, F.

10.1101/536458 — synthetic biology — Posted on 2019-01-31

161 The evolution of stage-specific virulence: differential selection of parasites in juveniles

Iritani, R.; Visher, E.; Boots, M.

10.1101/324632 — ecology — Posted on 2019-01-30

162 Afferent connections of the primary somatosensory cortex of the mouse for contextual and multisensory processing

Masse, I. O.; Blanchet-Godbout, S.; Bronchti, G.; Boire, D.

10.1101/514414 — neuroscience — Posted on 2019-01-30

163 Cross-disorder analysis of schizophrenia and 19 immune diseases reveals genetic correlation

Pouget, J. G.; Schizophrenia Working Group of the PGC, ; Han, B.; Wu, Y.; Mignot, E.; Ollila, H. M.; Barker, J.; Spain, S.; Dand, N.; Trembath, R.; Martin, J.; Mayes, M. D.; Bossini-Castillo, L.; Lopez-Isac, E.; Jin, Y.; Santorico, S.; Spritz, R. A.; Raychaudhuri, S.; Knight, J.

10.1101/068684 — genetics — Posted on 2019-01-30

164 Lobule-specific dosage considerations for cerebellar transcranial direct current stimulation during healthy aging - a computational modeling study using age-specific MRI templates

Rezaee, Z.; Dutta, A.

10.1101/535658 — neuroscience — Posted on 2019-01-30

165 Seasonal plasticity in anti-predatory strategies: matching of color and color preference for effective crypsis

van Bergen, E.; Beldade, P.

10.1101/253906 — evolutionary biology — Posted on 2019-01-30

166 Spectral tuning of adaptation supports coding of sensory context in auditory cortex

Lopez Espejo, M.; Schwartz, Z. P.; David, S. V.

10.1101/534537 — neuroscience — Posted on 2019-01-30

167 Structuring Time in Human Lateral Entorhinal Cortex

Bellmund, J. L. S.; Deuker, L.; Doeller, C. F.

10.1101/458133 — neuroscience — Posted on 2019-01-30

168 CO2 conversion to methane and biomass in obligate methylotrophic methanogens in marine sediments

Yin, X.; Wu, W.; Maeke, M.; Richter-Heitmann, T.; Kulkarni, A.; Oni, O. E.; Wendt, J.; Elvert, M.; Friedrich, M. W.

10.1101/528562 — microbiology — Posted on 2019-01-30

169 Biased visibility in HiC datasets marks dynamically regulated condensed and decondensed chromatin states genome-wide.

Chandradoss, K. R.; Guthikonda, P. K.; Kethavath, S.; Dass, M.; Singh, H.; Nayak, R.; Kurukuti, S.; Sandhu, K. S.

10.1101/498006 — genomics — Posted on 2019-01-30

170 Lipid unsaturation properties govern the sensitivity of membranes to photo-induced oxidative stress

Bour, A.; Kruglik, S. G.; Chabanon, M.; Rangamani, P.; Puff, N.; Bonneau, S.

10.1101/451591 — biophysics — Posted on 2019-01-30

171 Distinct characteristics of genes associated with phenome-wide variation in maize (Zea mays)

Liang, Z.; Qiu, Y.; Schnable, J.

10.1101/534503 — bioinformatics — Posted on 2019-01-30

172 The inhibition of automatic imitation: a meta-analysis and synthesis of fMRI studies

Darda, K. M.; Ramsey, R.

10.1101/334938 — neuroscience — Posted on 2019-01-30

173 Multimodal cell type correspondence by intersectional mFISH in intact tissues

Nicovich, P. R.; Taormina, M. J.; Baker, C. A.; Nguyen, T. N.; Thomsen, E. R.; Garren, E.; Long, B.; Gorham, M.; Miller, J.; Hage, T.; Bosma-Moody, A.; Murphy, G. J.; Levi, B. P.; Close, J. L.; Tasic, B.; Lein, E. S.; Zeng, H.

10.1101/525451 — neuroscience — Posted on 2019-01-30

174 Horizontal gene transfer as an indispensible driver for Neocallimastigomycota evolution into a distinct gut-dwelling fungal lineage

Murphy, C.; Youssef, N.; Hanafy, R. A.; Couger, M.; Stajich, J. E.; Wang, Y.; Baker, K.; Dagar, S.; Griffith, G.; Farag, I.; Callaghan, T.; Elshahed, M. S.

10.1101/487215 — microbiology — Posted on 2019-01-30

175 The Atypical Cyclin-Like Protein Spy1 Overrides p53-Mediated Tumour Suppression and Promotes Susceptibility to Breast Tumorigenesis

Fifield, B.-A.; Qemo, I.; Kirou, E.; Cardiff, R. D.; Porter, L. A.

10.1101/535310 — cancer biology — Posted on 2019-01-30

176 Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail

Raasakka, A.; Ruskamo, S.; Barker, R.; Krokengen, O. C.; Vatne, G. H.; Kristiansen, C. K.; Hallin, E. I.; Skoda, M. W.; Bergmann, U.; Wacklin-Knecht, H.; Jones, N. C.; Hoffmann, S. V.; Kursula, P.

10.1101/535013 — biophysics — Posted on 2019-01-30

177 Magnetic Ultrathin Tissue Sections for Ease of Light and Electron Microscopy

Koestinger, G.; During, D.; Rickauer, S.; Leite, V.; Yamahachi, H.; Csucs, G.; Hahnloser, R. H.

10.1101/532549 — neuroscience — Posted on 2019-01-30

178 Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes

Karczewski, K. J.; Francioli, L. C.; Tiao, G.; Cummings, B. B.; Alföldi, J.; Wang, Q.; Collins, R. L.; Laricchia, K. M.; Ganna, A.; Birnbaum, D. P.; Gauthier, L. D.; Brand, H.; Solomonson, M.; Watts, N. A.; Rhodes, D.; Singer-Berk, M.; Seaby, E. G.; Kosmicki, J. A.; Walters, R. K.; Tashman, K.; Farjoun, Y.; Banks, E.; Poterba, T.; Wang, A.; Seed, C.; Whiffin, N.; Chong, J. X.; Samocha, K. E.; Pierce-Hoffman, E.; Zappala, Z.; O'Donnell-Luria, A. H.; Vallabh Minikel, E.; Weisburd, B.; Lek, M.; Ware, J. S.; Vittal, C.; Armean, I. M.; Bergelson, L.; Cibulskis, K.; Connolly, K. M.; Covarrubias, M

10.1101/531210 — genomics — Posted on 2019-01-30

179 BELLA: Berkeley Efficient Long-Read to Long-Read Aligner and Overlapper

Guidi, G.; Ellis, M.; Rokhsar, D.; Yelick, K.; Buluc, A.

10.1101/464420 — bioinformatics — Posted on 2019-01-30

180 PGxCorpus: a Manually Annotated Corpus for Pharmacogenomics

Legrand, J.; Gogdemir, R.; Bousquet, C.; Dalleau, K.; Devignes, M.-D.; Digan, W.; Lee, C.-J.; Ndiaye, N.-C.; Petitpain, N.; Ringot, P.; Smail-Tabbone, M.; Toussaint, Y.; Coulet, A.

10.1101/534388 — bioinformatics — Posted on 2019-01-30

181 Saccade countermanding reflects automatic inhibition as well as top-down cognitive control

Bompas, A.; Campbell, A. E.; Sumner, P.

10.1101/535104 — animal behavior and cognition — Posted on 2019-01-30

182 Sex differences in the neural correlates of age-related episodic memory decline

Subramaniapillai, S.; Rajagopal, S.; Elshiekh, A.; Pasvanis, S.; Ankudowich, E.; Rajah, M. N.

10.1101/535617 — neuroscience — Posted on 2019-01-30

183 Heritable variation in bleaching responses and its functional genomic basis in reef-building corals (Orbicella faveolata)

Dziedzic, K.; Elder, H.; Tavalire, H. F.; Meyer, E.

10.1101/185595 — evolutionary biology — Posted on 2019-01-30

184 On estimating evolutionary probabilities of population variants

Kumar, S.; Patel, R.

10.1101/475475 — evolutionary biology — Posted on 2019-01-30

185 Long-term Brillouin imaging of live cells with reduced absorption-mediated damage at 660nm wavelength

Nikolic, M.; Scarcelli, G.

10.1101/535419 — biophysics — Posted on 2019-01-30

186 Monkey EEG links neuronal color and motion information across species and scales

Sandhaeger, F.; von Nicolai, C.; Miller, E. K.; Siegel, M.

10.1101/534990 — neuroscience — Posted on 2019-01-30

187 Differential expression feature extraction (DEFE) and its application in RNA-seq data analysis

Pan, Y.; Li, Y.; Liu, Z.; Surendra, A.; Wang, L.; Foroud, N. A.; Goyal, R. K.; Ouellet, T.; Fobert, P. R.

10.1101/511188 — genomics — Posted on 2019-01-30

188 Genetic variants of calcium and vitamin D metabolism in kidney stone disease

Howles, S. A.; Wiberg, A.; Goldsworthy, M.; Bayliss, A. L.; Grout, E.; Tanikawa, C.; Kamatani, Y.; Terao, C.; Takahashi, A.; Kubo, M.; Matsuda, K.; Thakker, R. V.; Turney, B. W.; Furniss, D.

10.1101/515882 — genomics — Posted on 2019-01-30

189 An empirical test of the role of small-scale transmission in large-scale disease dynamics

Mihaljevic, J. R.; Polivka, C. M.; Mehmel, C. J.; Li, C.; Dukic, V.; Dwyer, G.

10.1101/285080 — ecology — Posted on 2019-01-30

190 Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

Booth, A. J.; Yue, Z.; Eykelenboom, J. K.; Stiff, T.; Luxton, G. G.; Hochegger, H.; Tanaka, T. U.

10.1101/459750 — cell biology — Posted on 2019-01-30

191 BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology

10.1101/535682 — cell biology — Posted on 2019-01-30

192 Gene Info: A tool for facile retrieval of gene product information on any website

Knight, J. D. R.; Samavarchi-Tehrani, P.; Tyers, M.; Gingras, A.-C.

10.1101/532523 — bioinformatics — Posted on 2019-01-30

193 Inference of clonal selection in cancer populations using single-cell sequencing data

Skums, P.; Tsyvina, V.; Zelikovsky, A.

10.1101/465211 — bioinformatics — Posted on 2019-01-30

194 EEG signal diversity during propofol sedation: an increase in sedated but responsive, a decrease in sedated and unresponsive subjects

Bola, M.; Orlowski, P.; Plomecka, M.; Marchewka, A.

10.1101/444281 — neuroscience — Posted on 2019-01-30

195 Do Brucella Antibody Titers Correlate with Clinical Outcomes and Culture Positivity of Brucellosis?

Alsubaie, S. A.; Turkistani, S. A.; Zeaiter, A. A.; Thabit, A. K.

10.1101/534941 — immunology — Posted on 2019-01-30

196 Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single, Candida albicans infected macrophages

Munoz, J. F.; Delorey, T.; Ford, C. B.; Li, B. Y.; Thompson, D. A.; Rao, R. P.; Cuomo, C.

10.1101/350322 — genomics — Posted on 2019-01-30

197 Individual- versus group-optimality in the production of secreted bacterial compounds

Schiessl, K.; Ross-Gillespie, A.; Cornforth, D. M.; Weigert, M.; Bigosch, C.; Brown, S. P.; Ackermann, M.; Kummerli, R.

10.1101/094086 — evolutionary biology — Posted on 2019-01-30

198 Sulfur reduction coupling with anaerobic ammonium oxidation drives proto-anabolic networks

Bao, P.; Li, G.-X.; Li, H.

10.1101/461707 — biochemistry — Posted on 2019-01-30

199 Reliability and correlates of intra-individual variability in the oculomotor system

Perquin, M.; Bompas, A.

10.1101/535344 — neuroscience — Posted on 2019-01-30

200 The development, recognition, and learning mechanisms of animal-like neural network

Qi, F.

10.1101/535724 — neuroscience — Posted on 2019-01-30

201 A neural correlate of image memorability

Jaegle, A.; Mehrpour, V.; Mohsenzadeh, Y.; Meyer, T.; Oliva, A.; Rust, N. C.

10.1101/535468 — neuroscience — Posted on 2019-01-30

202 The simulation extrapolation technique meets ecology and evolution: A general and intuitive method to account for measurement error

Ponzi, E.; Keller, L. F.; Muff, S.

10.1101/535054 — evolutionary biology — Posted on 2019-01-30

203 Stable transgenesis in Astyanax mexicanus using the Tol2 transposase system.

Stahl, B. A.; Peuss, R.; McDole, B.; Kenzior, A.; Jaggard, J. B.; Gaudenz, K.; Krishnan, J.; McGaugh, S. E.; Duboue, E. R.; Keene, A. C.; Rohner, N.

10.1101/535740 — developmental biology — Posted on 2019-01-30

204 Genome-Wide Association Study and Pathway-Level Analysis of Kernel Color in Maize

Owens, B. F.; Mathew, D.; Diepenbrock, C.; Tiede, T.; Wu, D.; Mateos-Hernandez, M.; Gore, M. A.; Rocheford, T.

10.1101/535872 — plant biology — Posted on 2019-01-30

205 Age- and reserve-related increases in fronto-parietal and anterior hippocampal activity during episodic encoding predict subsequent memory

Elshiekh, A.; Subramaniapillai, S.; Rajagopal, S.; Pasvanis, S.; Ankudowich, E.; Rajah, M.

10.1101/535674 — neuroscience — Posted on 2019-01-30

206 Temporal control of inhibition via muscarinic acetylcholine receptor signaling generates ON and OFF selectivity in a simple visual circuit

Bo, Q.; Humberg, T.-H.; Kim, A.; Kim, H.; Short, J.; Diao, F.; White, B. H.; Sprecher, S. G.; Yuan, Q.

10.1101/535427 — neuroscience — Posted on 2019-01-30

207 The lymphoid-associated interleukin 7 receptor (IL-7R) regulates tissue resident macrophage development

Leung, G.; Cool, T.; Valencia, C.; Worthington, A.; Beaudin, A.; Forsberg, C.

10.1101/534859 — immunology — Posted on 2019-01-30

208 Thymosin β4 mediates vascular protection via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)

Munshaw, S.; Bruche, S.; Patel, J.; Redpath, A. N.; Dube, K. N.; Davies, R.; Neal, G.; Lee, R.; Handa, A.; Channon, K. M.; Smart, N.

10.1101/535351 — cell biology — Posted on 2019-01-30

209 Contextual fear learning and memory differ between stress coping styles in zebrafish

Baker, M. R.; Wong, R. Y.

10.1101/535294 — animal behavior and cognition — Posted on 2019-01-30

210 The striking flower-in-flower phenotype of Arabidopsis thaliana Nossen (No-0) is caused by a novel LEAFY allele

Mohrholz, A.; Sun, H.; Gloeckner, N.; Hummel, S.; Kolukisaoglu, U.; Schneeberger, K.; Harter, K.

10.1101/535120 — plant biology — Posted on 2019-01-30

211 Stimulation of the vagus nerve reduces learning in a go/no-go reinforcement learning task

Kuehnel, A.; Teckentrup, V.; Neuser, M. P.; Huys, Q. J. M.; Burrasch, C.; Walter, M.; Kroemer, N. B.

10.1101/535260 — neuroscience — Posted on 2019-01-30

212 Perfect adaptation of CD8+ T cell responses to constant antigen input over a wide range of affinity is overcome by costimulation

Trendel, N. C.; Kruger, P.; Nguyen, J.; Gaglione, S.; Dushek, O.

10.1101/535385 — immunology — Posted on 2019-01-30

213 HSB-1 inhibition and HSF-1 overexpression trigger overlapping transcriptional changes to promote longevity in Caenorhabditis elegans

Sural, S.; Lu, T.-C.; Jung, S. A.; Hsu, A.-L.

10.1101/535864 — genetics — Posted on 2019-01-30

214 Predator-prey nutrient competition undermines predator coexistence

Klauschies, T.; Gaedke, U.

10.1101/535195 — ecology — Posted on 2019-01-30

215 Invasive Siberian chipmunks Eutamias sibiricus in Italy: a socio-ecological analysis indicates that they could, and should, be removed

Cerri, J.; Mori, E.; Zozzoli, R.; Gigliotti, A.; Chirco, A.; Bertolino, S.

10.1101/535088 — ecology — Posted on 2019-01-30

216 PRINCIPAL COMPONENT ANALYSIS AND ITS GENERALIZATIONSFOR ANY TYPE SEQUENCE (PCA-SEQ)

Efimov, V. M.; Efimov, K. V.; Kovaleva, V. Y.

10.1101/535112 — bioinformatics — Posted on 2019-01-30

217 Effect of nitrite on neural activity in the healthy brain

Franko, E.; Ezra, M.; Crockett, D.; Joly, O.; Pattinson, K.

10.1101/535336 — neuroscience — Posted on 2019-01-30

218 Dissociating neural activity associated with the subjective phenomenology of monocular stereopsis: an EEG study

Uji, M.; Jentzsch, I.; Redburn, J.; Vishwanath, D.

10.1101/535203 — neuroscience — Posted on 2019-01-30

219 Interspecies bacterial competition determines community assembly in the C. elegans intestine

Ortiz Lopez, A.; Vega, N. M.; Gore, J.

10.1101/535633 — microbiology — Posted on 2019-01-30

220 Macrophage-specific NF-kappa B activation dynamics can segregate inflammatory bowel disease patients

Papoutsopoulou, S.; Burkitt, M. D.; Bergey, F.; England, H.; Hough, R.; Schmidt, L.; Spiller, D. G.; White, M. H.; Paszek, P.; Jackson, D. A.; Martins Dos Santos, V. A.; Sellge, G.; Pritchard, D. M.; Campbell, B. J.; Muller, W.; Probert, C.

10.1101/535096 — immunology — Posted on 2019-01-30

221 A blood-based prognostic biomarker in inflammatory bowel disease

Biasci, D.; Lee, J. C.; Noor, N. M.; Pombal, D. R.; Lewis, N.; Ahmad, T.; Hart, A.; Parkes, M.; McKinney, E. F.; Lyons, P. A.; Smith, K. G.

10.1101/535153 — genomics — Posted on 2019-01-30

222 The genetic structure of the European black pine (Pinus nigra Arnold) is shaped by its recent Holocene demographic history.

Giovannelli, G.; Scotti-Saintagne, C.; Scotti, I.; Roig, A.; Spanu, I.; Vendramin, G. G.; Guibal, F.; Fady, B.

10.1101/535591 — ecology — Posted on 2019-01-30

223 Argonaute bypasses cellular obstacles without hindrance during target search

Cui, T. J.; Klein, M.; Hegge, J.; Chandradoss, S. D.; van der Oost, J.; Depken, M.; Joo, C.

10.1101/535575 — biophysics — Posted on 2019-01-30

224 A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery

Choi, Y.-R.; Collins, K.; Springer, L.; Pferdehirt, L.; Ross, A.; Wu, C.-L.; Moutos, F.; Harasymowicz, N.; Brunger, J.; Pham, C.; Guilak, F.

10.1101/535609 — synthetic biology — Posted on 2019-01-30

225 Inability to improve performance with control shows limited access to inner states

Perquin, M.; Yang, J.; Teufel, C.; Sumner, P.; Hedge, C.; Bompas, A.

10.1101/535187 — neuroscience — Posted on 2019-01-30

226 Biological Impact of a Large Scale Genomic Inversion that Grossly Disrupts the Relative Positions of the Origin and Terminus Loci of the Streptococcus pyogenes Chromosome

Savic, D. J.; Nguyen, S. V.; McCullor, K. A.; McShan, W. M.

10.1101/534933 — microbiology — Posted on 2019-01-30

227 Energy Landscape of the Domain Movement in Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase

de Azevedo, E. C.; Nascimento, A. S.

10.1101/535138 — biophysics — Posted on 2019-01-30

228 Inoculum size effects in blaIMP-6 and plasmid-mediated quinolone resistance gene-positive Enterobacteriaceae in Japan

Ogawa, Y.; Nakano, R.; Kasahara, K.; Mizuno, T.; Hirai, N.; Nakano, A.; Suzuki, Y.; Kakuta, N.; Masui, T.; Yano, H.; Mikasa, K.

10.1101/534958 — microbiology — Posted on 2019-01-30

229 Comparison of the bacterial and methanotrophic diversities between an Italian paddy field and its neighboring meadow

Ghashghavi, M.; Hester, E. R.; Oliver, V.; Luke, C.; Jetten, M. S. M.; Lucker, S.

10.1101/535229 — microbiology — Posted on 2019-01-30

230 Towards a low CO2 emission building material employing bacterial metabolism in a two-step process of limestone dissolution and recrystallization: The bacterial system and prototype production

Royne, A.; Phua, Y. J.; Le, S. B.; Eikjeland, I. G.; Josefsen, K. D.; Markussen, S.; Myhr, A.; Throne-Holst, H.; Sikorski, P.; Wentzel, A.

10.1101/535161 — microbiology — Posted on 2019-01-30

231 Extremely Drug-Resistant Pseudomonas aeruginosa ST309 Harboring Tandem GES Enzymes: A Newly Emerging Threat in the United States

Khan, A.; Tran, T. T.; Rios, R.; Hanson, B.; Shropshire, W. C.; Sun, Z.; Diaz, L.; Dinh, A. Q.; Wanger, A.; Ostrosky-Zeichner, L.; Palzkill, T.; Arias, C. A.; Miller, W. R.

10.1101/535302 — microbiology — Posted on 2019-01-30

232 Population history and gene divergence in Native Mexicans inferred from 76 human exomes

Avila-Arcos, M. C.; McManus, K. F.; Sandoval, K.; Rodriguez-Rodriguez, J. E.; Martin, A. R.; Luisi, P.; Villa-Islas, V.; Penaloza-Espinosa, R. I.; Eng, C.; Huntsman, S.; Burchard, E. G.; Gignoux, C. R.; Bustamante, C. D.; Moreno-Estrada, A.

10.1101/534818 — genomics — Posted on 2019-01-30

233 Localizing the chaperone activity of erythroid spectrin

Bose, D.; Chakrabarti, A.

10.1101/534982 — biochemistry — Posted on 2019-01-30

234 Porthole and Stormcloud: Tools for visualisation of spatiotemporal M/EEG statistics

Taylor, J. A.; Garrido, M. I.

10.1101/534784 — neuroscience — Posted on 2019-01-30

235 The development of spatiotemporal organization of episodic memory in children and its disruption in Williams Syndrome

Mastrogiuseppe, M.; Bertelsen, N.; Bedeschi, M. F.; Lee, S. A.

10.1101/534743 — neuroscience — Posted on 2019-01-30

236 The vagino-cervical microbiome as a woman's life history

Jie, Z.; Chen, C.; Hao, L.; Li, F.; Tian, L.; Tong, X.; Song, L.; Cai, K.; Yu, X.; Li, Y.; Rao, W.; Liao, Y.; Zhou, D.; Qiu, X.; Chen, X.; Zi, J.; Liu, N.; Zhang, W.; Liu, X.; Xiao, L.; Xu, X.; Yang, H.; Wang, J.; Hou, Y.; Kristiansen, K.; Jia, H.

10.1101/533588 — microbiology — Posted on 2019-01-30

237 Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding.

Lee, W.; Windley, M. J.; Perry, M. D.; Vandenberg, J. I.; Hill, A. P.

10.1101/534867 — pharmacology and toxicology — Posted on 2019-01-30

238 Dual forms of aging-related NADPH diaphorase neurodegeneration in the sacral spinal cord of aged non-human primates

Li, Y.; Wei, Z.; Jia, Y.; Hou, W.; Wang, Y.; Yu, S.; Shi, G.; Du, G.; Tan, H.

10.1101/527358 — neuroscience — Posted on 2019-01-30

239 Increased Replication Rates of Dissimilatory Nitrogen-Reducing Bacteria Leads to Decreased Anammox Reactor Performance

Keren, R.; Lawrence, J.; Zhuang, W.-Q.; Jenkins, D.; Banfield, J. F.; Alvarez-Cohen, L.; Zhou, L.; Yu, K.

10.1101/534925 — microbiology — Posted on 2019-01-30

240 Genome-wide copy number variation-, validation- and screening study implicates a novel copy number polymorphism associated with suicide attempts in major depressive disorder

Rao, S.; Shi, M.; Han, X.; Lam, M. H. B.; Liu, G.; Wing, Y. K.; So, H.-C.; Waye, M. M. Y.

10.1101/534909 — genetics — Posted on 2019-01-30

241 A Gradient of Hippocampal Inputs to the Medial Mesocortex

Ferreira-Fernandes, E.; Quintino, C.; Remondes, M.

10.1101/535047 — neuroscience — Posted on 2019-01-30

242 Multi-Neuromodulator Measurements across Fronto-Striatal Network Areas of the Behaving Macaque using Solid-Phase Microextraction

Hassani, S.-A.; Lendor, S.; Boyaci, E.; Pawliszyn, J.; Womelsdorf, T.

10.1101/534651 — neuroscience — Posted on 2019-01-30

243 Yellow strawberries and red bananas: The influence of object-colour knowledge on emerging object representations in the brain

Teichmann, L.; Quek, G. L.; Robinson, A.; Grootswagers, T.; Carlson, T.; Rich, A.

10.1101/533513 — neuroscience — Posted on 2019-01-30

244 Cerebellar climbing fibers encode expected reward size

Larry, N.; Yarkoni, M.; Lixenberg, A.; Joshua, M.

10.1101/533653 — neuroscience — Posted on 2019-01-30

245 Multiple sources of Shh are critical for the generation and scaling of ventral spinal cord oligodendrocyte precursor populations.

Starikov, L.; Kottmann, A. H.

10.1101/534750 — developmental biology — Posted on 2019-01-30

246 The Metabolites NADP+ and NADPH are the Targets of the Circadian Protein Nocturnin (Curled)

Estrella, M. A.; Du, J.; Chen, L.; Rath, S.; Prangley, E.; Chitrakar, A.; Aoki, T.; Schedl, P.; Rabinowitz, J.; Korennykh, A.

10.1101/534560 — biophysics — Posted on 2019-01-30

247 Design and Synthesis of Pleated DNA Origami Nanotubes with Adjustable Diameters

Berengut, J. F.; Ruan, J.; Kawamoto, A.; Lee, L. K.

10.1101/534792 — synthetic biology — Posted on 2019-01-30

248 Capturing cell type-specific chromatin structural patterns by applying topic modeling to single-cell Hi-C data

Kim, H.-J.; Yardimici, G. G.; Bonora, G.; Ramani, V.; Liu, J.; Qiu, R.; Lee, C.; Hesson, J.; Ware, C. B.; Shendure, J.; Duan, Z.; Noble, W. S.

10.1101/534800 — genomics — Posted on 2019-01-30

249 The systemin signaling cascade as derived from phosphorylation time courses under stimulation by systemin and its inactive Thr17Ala (A17) analog

Hai Ahmad, F.; Wu, X. N.; Stintzi, A.; Schaller, A.; Schulze, W. X.

10.1101/535070 — plant biology — Posted on 2019-01-30

250 Translational landscape in tomato revealed by transcriptome assembly and ribosome profiling

Wu, H.-Y. L.; Song, G.; Walley, J. W.; Hsu, P. Y.

10.1101/534677 — plant biology — Posted on 2019-01-30

251 Genomics, evolutionary history and diagnostics of the Alternaria alternata species group including apple and Asian pear pathotypes

Armitage, A. D.; Cockerton, H. M.; Sreenivasaprasad, S.; Woodhall, J.; Lane, C.; Harrison, R. J.; Clarkson, J. P.

10.1101/534685 — microbiology — Posted on 2019-01-30

252 Selection, succession and stabilization of soil microbial consortia

Zegeye, E. K.; Brislawn, C. J.; Farris, Y.; Fansler, S. J.; Hofmockel, K. S.; Jansson, J. K.; Wright, A. T.; Graham, E. B.; Naylor, D.; McClure, R. S.; Bernstein, H. C.

10.1101/533604 — microbiology — Posted on 2019-01-30

253 Network Inference with Granger Causality Ensembles on Single-Cell Transcriptomic Data

Deshpande, A.; Chu, L.-F.; Stewart, R.; Gitter, A.

10.1101/534834 — bioinformatics — Posted on 2019-01-30

254 PerMemDB: a database for eukaryotic peripheral membrane proteins

Nastou, K. C.; Tsaousis, G. N.; Hamodrakas, S. J.; Iconomidou, V. A.

10.1101/531541 — bioinformatics — Posted on 2019-01-30

255 Illuminating the dark depths inside coral

Liu, C.; Cheng, S. H.; Lin, S.

10.1101/534842 — microbiology — Posted on 2019-01-30

256 Structural basis for transcription initiation by bacterial ECF σ factors

Li, L.; Fang, c.; Zhuang, N.; Wang, T.; Zhang, Y.

10.1101/534826 — microbiology — Posted on 2019-01-30

257 Characterizing and comparing missense variants in monogenic disease and in cancer

Yin, Y.; Moult, J.

10.1101/534693 — genomics — Posted on 2019-01-30

258 lncRNA Neat1 drives neuronal histone methylation and age-related memory impairments

Butler, A. A.; Johnston, D. R.; Kaur, S.; Lubin, F. D.

10.1101/531707 — neuroscience — Posted on 2019-01-30

259 Septin 9-containging filaments and Golgi assembly depend on two polybasic domains

Omrane, M.; Camara, A. S.; Taveneau, C.; Benzoubir, N.; Tubiana, T.; Yua, J.; Guerois, R.; Samuel, D.; Goud, B.; Pous, C.; Bressanelli, S.; Garratt, R. C.; Thiam, A. R.; Gassama-Diagne, A.

10.1101/535039 — cell biology — Posted on 2019-01-30

260 Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail

Raasakka, A.; Ruskamo, S.; Barker, R.; Krokengen, O. C.; Vatne, G. H.; Kristiansen, C. K.; Hallin, E. I.; Skoda, M. W.; Bergmann, U.; Wacklin-Knecht, H.; Jones, N. C.; Hoffmann, S. V.; Kursula, P.

10.1101/535013 — biophysics — Posted on 2019-01-30

261 Is Drosophila melanogaster Stress Odorant (dSO) really an alarm pheromone?

Yost, R. T.; Liang, E.; Stewart, M. P.; Chui, S.; Greco, A. F.; Long, S. Q.; McDonald, I. S.; McNeil, J. N.; Simon, A. F.

10.1101/534719 — animal behavior and cognition — Posted on 2019-01-30

262 Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

Giusti-Rodriguez, P. M.; Sullivan, P. F.

10.1101/406330 — genetics — Posted on 2019-01-30

263 Toward Health Management of Major Labour Force Generation by Using Infection Control Countermeasures for Haematobium Schistosomiasis -assumed to be related to occupational risk- in the Republic of Malawi

Mishima, N.; Nishiyama, T.; Amano, H.; Maeba, H.; Komai, Y.; Ng'ambi, S.; Kanda, S.; Miyake, M.; Lamaningao, P.; Shimono, T.; Darcy, A. W.; Tabuchi, K.; Kuroda, T.; Jemu, S. K.

10.1101/535542 — microbiology — Posted on 2019-01-30

264 Epigenetic Profiling Provides Insights into AIDS Resistance in African Green Monkey

Yuan, Z.; Zhou, X.

10.1101/535567 — microbiology — Posted on 2019-01-30

265 Dosimetric Study of Breast Scar Marker in Different Radiotherapy Dose Calculation Algorithms

Mohammed, A. A. A.; Abdullah, S. S.; Sulieman, A. A.; Mattar, I. H.; Ying, C. K.; Appalanaido, G. K.; Azahari, A. N.; Abdul Aziz, M. Z.

10.1101/535476 — cell biology — Posted on 2019-01-30

266 TRPV4 inhibition prevents increased water diffusion and blood-retina barrier breakdown in the retina of streptozotocin-induced diabetic mice.

thebault, s.; Orduna Rios, M.; Noguez Imm, R.; Hernandez Godinez, N. M.; Bautista Cortes, A. M.; Liedtke, W.; Martinez Torres, A.; Concha, L.

10.1101/535526 — physiology — Posted on 2019-01-30

267 A cross-sectional study to assess the magnitude of Hypertension and Type 2 Diabetes Mellitus in Hatcliffe, Harare

Gonde, L. L.; Chimbari, M. J. J.; Manyangadze, T.

10.1101/535450 — epidemiology — Posted on 2019-01-30

268 Convolutional and Recurrent Neural Network for Human Action Recognition: application on American Sign Language

Hernandez, V.; Suzuki, T.; Venture, G.

10.1101/535492 — bioengineering — Posted on 2019-01-30

269 Adherence rate to iron folic acid supplementation among pregnant women

Asmare, W. N.; Asmare, W. N.

10.1101/535534 — animal behavior and cognition — Posted on 2019-01-30

270 Maturity2, a novel regulator of flowering time in Sorghum bicolor, increases expression of SbPRR37 and SbCO in long days delaying flowering

Casto, A.; Mattison, A. J.; Olson, S. N.; Thakran, M.; Rooney, W. L.; Mullet, J. L.

10.1101/535484 — plant biology — Posted on 2019-01-30

271 Minimal effects of spargel (PGC-1α) overexpression in a Drosophila mitochondrial disease model

George, J.; Jacobs, H. T.

10.1101/529545 — molecular biology — Posted on 2019-01-30

272 Saccharomyces cerevisiae strains display robust phenotypes in the presence of Dyskeratosis congenita mutations in the Cbf5 gene

Kothe, U.; Ogailan, A. A.; Rintala-Dempsey, A. C.

10.1101/535443 — molecular biology — Posted on 2019-01-30

273 The molecular clock of Mycobacterium tuberculosis

Menardo, F.; Duchene, S.; Brites, D.; Gagneux, S.

10.1101/532390 — evolutionary biology — Posted on 2019-01-30

274 The Impact of Uremia and Intestinal Dysbiosis on Hepatic Drug Metabolism in a Rat Model of Progressive Chronic Kidney Disease

Hartjes, E. D.; Lim, Y. J.; Velenosi, T. J.; Al, K. F.; Macklaim, J. M.; Kucey, A. S.; Reid, G.; Burton, J. P.; Gloor, G. B.; Urquhart, B. L.

10.1101/531939 — pharmacology and toxicology — Posted on 2019-01-29

275 Intra-bin structural variant segmentation for whole-genome sequencing data using U-net

Zhang, Y.-z.; Imoto, S.; Miyano, S.; Yamaguchi, R.

10.1101/503649 — bioinformatics — Posted on 2019-01-29

276 Complementary roles for ventral pallidum cell types and their projections in relapse

Prasad, A. A.; Xie, C.; Chaichim, C.; Killcross, S.; Power, J. M.; McNally, G. P.

10.1101/533554 — neuroscience — Posted on 2019-01-29

277 Opioids for breathlessness: Psychological and neural factors influencing response variability

Abdallah, S. J.; Faull, O. K.; Wanigasekera, V.; Finnegan, S. L.; Jensen, D.; Pattinson, K.

10.1101/344523 — neuroscience — Posted on 2019-01-29

278 CRISPR/Cas9-mediated gene deletion of the ompA gene in an Enterobacter gut symbiont impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

Hegde, S.; Nilyanimit, P.; Kozlova, E.; Narra, H. P.; Sahni, S. K.; Hughes, G. L.

10.1101/389957 — microbiology — Posted on 2019-01-29

279 3D super-resolution imaging using a generalized and scalable progressive refinement method on sparse recovery (PRIS)

Yi, X.; Piestun, R.; Weiss, S.

10.1101/532143 — bioengineering — Posted on 2019-01-29

280 Stochastic modelling reveals mechanisms of metabolic heterogeneity

Tonn, M. K.; Thomas, P.; Barahona, M.; Oyarzun, D. A.

10.1101/522425 — systems biology — Posted on 2019-01-29

281 Facilitating open-science with realistic fMRI simulation: validation and application

Ellis, C.; Baldassano, C.; Schapiro, A. C.; Cai, M. B.; Cohen, J. D.

10.1101/532424 — neuroscience — Posted on 2019-01-29

282 Parasite dispersal influences introgression rate

Dona, J.; Sweet, A.; Johnson, K.

10.1101/527226 — evolutionary biology — Posted on 2019-01-29

283 Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities

Nichols, C. A.; Gibson, W. J.; Brown, M. S.; Kosmicki, J. A.; Busanovich, J. P.; Wei, H.; Urbanski, L. M.; Curimjee, N.; Berger, A. C.; Gao, G. F.; Cherniack, A. D.; Dhe-Paganon, S.; Paolella, B. R.; Beroukhim, R.

10.1101/534529 — cancer biology — Posted on 2019-01-29

284 BELLA: Berkeley Efficient Long-Read to Long-Read Aligner and Overlapper

Guidi, G.; Ellis, M.; Rokhsar, D.; Yelick, K.; Buluc, A.

10.1101/464420 — bioinformatics — Posted on 2019-01-29

285 Antero-posterior versus lateral vestibular input processing in human visual cortex

Aedo-Jury, F.; Cottereau, B. R.; Celebrini, S.; Severac Cauquil, A.

10.1101/530808 — neuroscience — Posted on 2019-01-29

286 Perturbations of a Kinase-Pseudokinase Module Activate Plant Immunity

Bastedo, D. P.; Seto, D.; Martel, A.; Khan, M.; Kireeva, I.; Zhang, J.; Masud, W.; Millar, D.; Lee, J. Y.; Lee, A. H.-Y.; Gong, Y.; Santos-Severino, A.; Guttman, D. S.; Desveaux, D.

10.1101/531665 — molecular biology — Posted on 2019-01-29

287 iDamage: a method to integrate modified DNA into the yeast genome

Maslowska, K.; Laureti, L.; Pages, V.

10.1101/510966 — molecular biology — Posted on 2019-01-29

288 The SUMO ligase Su(var)2-10 links piRNA-guided target recognition to chromatin silencing

Ninova, M.; Chen, Y.-C. A.; Godneeva, B.; Rogers, A. K.; Luo, Y.; Aravin, A. A.; Fejes Toth, K.

10.1101/533091 — molecular biology — Posted on 2019-01-29

289 Stochastic transcriptional pulses orchestrate flagellum biosynthesis in E. coli

Kim, J. M.; Alcala-Garcia, M.; Balleza, E.; Cluzel, P.

10.1101/508580 — microbiology — Posted on 2019-01-29

290 Prediction of Algal Blooms in the Great Lakes through a Convolution Neural Network of Remote Sensing Data

Srinivasan, K.; Duvvur, V.; Hess, D.

10.1101/450551 — ecology — Posted on 2019-01-29

291 Transection of the ventral hippocampal commissure impairs spatial but not contextual memory in split-brain mice

Jordan, J.; Tong, Y.; Pytte, C.

10.1101/437491 — neuroscience — Posted on 2019-01-29

292 Sex differences in brain correlates of STEM anxiety

Gonzalez, A. A.; Bottenhorn, K. L.; Bartley, J. E.; Hayes, T.; Riedel, M. C.; Salo, T.; Bravo, E.; Odean, R.; Nazareth, A.; Laird, R. W.; Sutherland, M. T.; Brewe, E.; Pruden, S. M.; Laird, A. R.

10.1101/528075 — neuroscience — Posted on 2019-01-29

293 Probabilities of tree topologies with temporal constraints and diversification shifts

Didier, G.

10.1101/376756 — evolutionary biology — Posted on 2019-01-29

294 Community-level impacts of spatial repellents for control of diseases vectored by Aedes aegypti mosquitoes

ten Bosch, Q. A.; Wagman, J. M.; Castro-Llanos, F.; Achee, N. L.; Grieco, J. P.; Perkins, A.

10.1101/501700 — epidemiology — Posted on 2019-01-29

295 The regulation of HAD-like phosphatases by signaling pathways modulates cellular resistance to the metabolic inhibitor, 2-deoxyglucose

Defenouillere, Q.; Verraes, A.; Laussel, C.; Friedrich, A.; Schacherer, J.; Leon, S.

10.1101/504134 — cell biology — Posted on 2019-01-29

296 Experimentally reduced insulin/IGF-1 signalling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring

Lind, M. I.; Ravindran, S.; Sekajova, Z.; Carlsson, H.; Hinas, A.; Maklakov, A. A.

10.1101/405019 — evolutionary biology — Posted on 2019-01-29

297 Sexual selection affects the evolution of contact pheromones in Drosophila melanogaster populations isolated by differential sexual conflict

Dutta, R.; Chechi, T. S.; Prasad, N. G.

10.1101/351718 — evolutionary biology — Posted on 2019-01-29

298 Eco-evolutionary processes underlying early warning signals of population declines

Baruah, G.; Clements, C. F.; Ozgul, A.

10.1101/422915 — ecology — Posted on 2019-01-29

299 Primary Cilium Disassembly in Mammalian Cells Occurs Predominantly by Whole-Cilium Shedding

Mirvis, M.; Siemers, K. A.; Nelson, W. J.; Stearns, T.

10.1101/433144 — cell biology — Posted on 2019-01-29

300 Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments

Clarke, E. L.; Taylor, L. J.; Zhao, C.; Connell, J.; Lee, J.-J.; Fett, B.; Bushman, F. D.; Bittinger, K.

10.1101/326363 — bioinformatics — Posted on 2019-01-29

301 Topological Reinforcement as a Principle of Modularity Emergence in Brain Networks

Damicelli, F.; Hilgetag, C. C.; Hütt, M.-T.; Messe, A.

10.1101/408278 — neuroscience — Posted on 2019-01-29

302 Empowering conservation practice with efficient and economical genotyping from poor quality samples

Natesh, M.; Taylor, R.; Truelove, N.; Hadly, E.; Palumbi, S.; Petrov, D.; Ramakrishnan, U.

10.1101/349472 — genomics — Posted on 2019-01-29

303 Efficient Merging of Genome Profile Alignments

Hennig, A.; Nieselt, K.

10.1101/309047 — bioinformatics — Posted on 2019-01-29

304 Characteristics of Beta Waveform Shape in Parkinson's Disease Detected with Scalp Electroencephalography

Jackson, N.; Cole, S. R.; Voytek, B.; Swann, N. C.

10.1101/534396 — neuroscience — Posted on 2019-01-29

305 Testing hypotheses about the microbiome using the linear decomposition model

Hu, Y.; Satten, G. A.

10.1101/229831 — bioinformatics — Posted on 2019-01-29

306 Towards building an automated bioinformatician: more accurate transcript assembly via parameter advising

DeBlasio, D.; Kim, K.; Kingsford, C.

10.1101/342865 — bioinformatics — Posted on 2019-01-29

307 Fear in dreams and in wakefulness: evidence for day/night affective homeostasis

Sterpenich, V.; Perogamvros, L.; Tononi, G.; Schwartz, S.

10.1101/534099 — neuroscience — Posted on 2019-01-29

308 A novel plasmid-transcribed regulatory sRNA, QfsR, controls chromosomal polycistronic mRNAs in Agrobacterium tumefaciens

Diel, B.; Dequivre, M.; Wisniewski-Dye, F.; Vial, L.; Hommais, F.

10.1101/533729 — genomics — Posted on 2019-01-29

309 PGxCorpus: a Manually Annotated Corpus for Pharmacogenomics

Legrand, J.; Gogdemir, R.; Bousquet, C.; Dalleau, K.; Devignes, M.-D.; Digan, W.; Lee, C.-J.; Ndiaye, N.-C.; Petitpain, N.; Ringot, P.; Smail-Tabbone, M.; Toussaint, Y.; Coulet, A.

10.1101/534388 — bioinformatics — Posted on 2019-01-29

310 Soybean Haplotype Map (GmHapMap): A Universal Resource for Soybean Translational and Functional Genomics

Torkamaneh, D.; Laroche, J.; Valliyodan, B.; O'Donoughue, L.; Cober, E.; Rajcan, I.; Vilela Abdelnoor, R.; Sreedasyam, A.; Schmutz, J.; Nguyen, H. T.; Belzile, F.

10.1101/534578 — plant biology — Posted on 2019-01-29

311 Distinct ROPGEFs successively drive polarization and outgrowth of root hairs

Philipp, D.; Reichelt, A.; Schmidt, V. A. F.; Mehlhorn, D. G.; Asseck, L. Y.; Stanley, C. E.; Keinath, N. F.; Evers, J. F.; Grefen, C.; Grossmann, G.

10.1101/534545 — cell biology — Posted on 2019-01-29

312 BlastPhyMe: A toolkit for rapid generation and analysis of protein-coding sequence datasets

Schott, R. K.; Gow, D.; Chang, B. S.

10.1101/059881 — bioinformatics — Posted on 2019-01-29

313 Imaging single-cell blood flow in the smallest to largest vessels in the living retina

Schallek, J.; Guevara-Torres, A.; Joseph, A.

10.1101/533919 — bioinformatics — Posted on 2019-01-29

314 Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction

Talkish, J.; Igel, H.; Hunter, O.; Horner, S. W.; Jeffrey, N. N.; Leach, J. R.; Jenkins, J. L.; Kielkopf, C. L.; Ares, M.

10.1101/534347 — molecular biology — Posted on 2019-01-29

315 SPIKEPIPE: A metagenomic pipeline for the accurate quantification of eukaryotic species occurrences and abundances using DNA barcodes or mitogenomes

Ji, Y.; Huotari, T.; Roslin, T.; Martin-Schmidt, N.; Wang, J.; Yu, D.; Ovaskainen, O.

10.1101/533737 — ecology — Posted on 2019-01-29

316 Three stages in the development of the cyst wall of the eye pathogen Acanthamoeba castellanii

Magistrado-Coxen, P.; Aqeel, Y.; Samuelson, J.

10.1101/534487 — cell biology — Posted on 2019-01-29

317 Spectral tuning of adaptation supports coding of sensory context in auditory cortex

Lopez Espejo, M.; Schwartz, Z. P.; David, S. V.

10.1101/534537 — neuroscience — Posted on 2019-01-29

318 An allele-specific functional SNP associated with two autoimmune diseases modulates IRF5 expression by long-range chromatin loop formation

Thynn, H. N.; Chen, X.-F.; Hu, W.-X.; Duan, Y.-Y.; Zhu, D.-L.; Chen, H.; Wang, N.-N.; Chen, H.-H.; Rong, Y.; Lu, B.-J.; Yang, M.; Jiang, F.; Dong, S.-S.; Guo, Y.; Yang, T.-L.

10.1101/533661 — genetics — Posted on 2019-01-29

319 Distinct characteristics of genes associated with phenome-wide variation in maize (Zea mays)

Liang, Z.; Qiu, Y.; Schnable, J.

10.1101/534503 — bioinformatics — Posted on 2019-01-29

320 A tunable microfluidic device enables cargo encapsulation by cell- or organelle-sized lipid vesicles comprising asymmetric lipid monolayers

Romanov, V.; McCullough, J.; Sharma, A.; Vershinin, M.; Gale, B. K.; Frost, A.

10.1101/534586 — bioengineering — Posted on 2019-01-29

321 Reevaluating the Fusobacterium Virulence Factor Landscape

Umana, A.; Sanders, B. E.; Yoo, C. C.; Casasanta, M. A.; Udayasuryan, B.; Verbridge, S. S.; Slade, D. J.

10.1101/534297 — microbiology — Posted on 2019-01-29

322 Length of uninterrupted CAG repeats, independent of polyglutamine size, results in increased somatic instability and hastened age of onset in Huntington disease

Wright, G. E. B.; Collins, J. A.; Kay, C.; McDonald, C.; Dolzhenko, E.; Xia, Q.; Becanovic, K.; Semaka, A.; Nguyen, C. M.; Trost, B.; Richards, F.; Bijlsma, E. K.; Squitieri, F.; Scherer, S. W.; Eberle, M. A.; Yuen, R. K. C.; Hayden, M. R.

10.1101/533414 — genetics — Posted on 2019-01-29

323 Loss of CIC promotes mitotic dysregulation and chromosome segregation defects

Chittaranjan, S.; Song, J.; Chan, S. Y.; Lee, S. D.; Ahmad, S. T.; Brothers, W.; Corbett, R. D.; Gagliardi, A.; Lum, A.; Moradian, A.; Pleasance, S.; Coope, R.; Cairncross, J. G.; Yip, S.; Laks, E.; Aparicio, S. A.; Chan, J. A.; Hughes, C. S.; Morin, G. B.; LeBlanc, V. G.; Marra, M. A.

10.1101/533323 — cancer biology — Posted on 2019-01-29

324 Personalized Annotation-based Networks (PAN) for the Prediction of Breast Cancer Relapse

Nguyen, T.; Lee, S. C.; Quinn, T. P.; Truong, B.; Li, X.; Tran, T.; Venkatesh, S.; Le, T. D.

10.1101/534628 — bioinformatics — Posted on 2019-01-29

325 GIGI2: A Fast Approach for Parallel Genotype Imputation in Large Pedigrees

Ullah, E.; Kunji, K.; Wijsman, E. M.; Saad, M.

10.1101/533687 — bioinformatics — Posted on 2019-01-29

326 Locality sensitive hashing for the edit distance

Marcais, G.; DeBlasio, D.; Pandey, P.; Kingsford, C.

10.1101/534446 — bioinformatics — Posted on 2019-01-29

327 Interplay of pericentromeric genome organization and chromatin landscape regulates the expression of Drosophila melanogaster heterochromatic genes

Saha, P.; Sowpati, D. T.; Srivastava, I.; Mishra, R.

10.1101/534065 — genomics — Posted on 2019-01-29

328 A sensory ecological perspective on mate sampling strategies: simulation models and an empirical test

Nandi, D.; Suswaram, M.; Balakrishnan, R.

10.1101/533489 — evolutionary biology — Posted on 2019-01-29

329 Neanderthal introgression reintroduced functional alleles lost in the human out of Africa bottleneck

Rinker, D. C.; Simonti, C.; McArthur, E.; Shaw, D.; Hodges, E.; Capra, J. A.

10.1101/533257 — evolutionary biology — Posted on 2019-01-29

330 The hidden costs of dietary restriction: implications for its evolutionary and mechanistic origins

McCracken, A. W.; Adams, G.; Hartshorne, L.; Simons, M. J. P.

10.1101/533711 — evolutionary biology — Posted on 2019-01-29

331 Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities

10.1101/534529 — cancer biology — Posted on 2019-01-29

332 Flexible Experimental Designs for Valid Single-cell RNA-sequencing Experiments Allowing Batch Effects Correction

Song, F.; Chan, G. M.; Wei, Y.

10.1101/533372 — bioinformatics — Posted on 2019-01-29

333 Towards a Gamete Matching Platform: Using Immunogenetics and Artificial Intelligence to Predict Recurrent Miscarriage

Mora-Sanchez, A.; Aguilar Salvador, D. I.; Nowak, I.

10.1101/534594 — bioinformatics — Posted on 2019-01-29

334 Cell Type Classification and Unsupervised MorphologicalPhenotype Identification from Low-Res Images with DeepLearning

Yao, K.; Rochman, N.; Sun, S.

10.1101/533216 — bioengineering — Posted on 2019-01-29

335 Sample preparation protocol enabling nano-to-mesoscopic mapping of cellular connectomes and their habitats in human tissues and organs

Ngo, L.; Nathanson, A.; Garbowski, T.; Knothe, U.; Zeidler, D.; Tate, M. L. K.

10.1101/533448 — systems biology — Posted on 2019-01-29

336 ClinGen Expert Clinical Validity Curation of 164 Hearing Loss Gene-Disease Pairs

DiStefano, M. T.; Hemphill, S. E.; Oza, A. M.; Siegert, R. K.; Gant, A. R.; Hughes, M. Y.; Cushman, B. J.; Azaiez, H.; Booth, K. T.; Chapin, A.; Duzkale, H.; Matsunaga, T.; Shen, J.; Zhang, W.; Kenna, M.; Schimmenti, L.; Tekin, M.; Rehm, H. L.; Abou Tayoun, A. N.; Amr, S. S.; ClinGen Hearing Loss Clinical Domain Working Group,

10.1101/534040 — genomics — Posted on 2019-01-29

337 Interacting cells driving the evolution of multicellular life cycles

Gao, Y.; Traulsen, A.; Pichugin, Y.

10.1101/533745 — evolutionary biology — Posted on 2019-01-29

338 Erosion of phylogenetic diversity in Neotropical bat assemblages: findings from a whole-ecosystem fragmentation experiment

Aninta, S. G.; Rocha, R.; Lopez-Baucells, A.; Meyer, C. F. J.

10.1101/534057 — ecology — Posted on 2019-01-29

339 Stool-derived eukaryotic RNA biomarkers for detection of high-risk adenomas

Barnell, E. K.; Kang, Y.; Barnell, A. R.; Campbell, K. M.; Kruse, K. R.; Wurtzler, E. M.; Griffith, M.; Chaudhuri, A. A.; Griffith, O. L.

10.1101/534412 — cancer biology — Posted on 2019-01-29

340 Completing the ENCODE3 compendium yields accurate imputations across a variety of assays and human biosamples

Schreiber, J.; Bilmes, J.; Noble, W.

10.1101/533273 — bioinformatics — Posted on 2019-01-29

341 Heterologous expression of Stlac2, a laccase isozyme of Setosphearia turcica, and the ability of decolorization of malachite green

Liu, N.; Shen, S.; Jia, H.; Yang, B.; Guo, X.; Si, H.; Cao, Z.; Dong, J.

10.1101/533562 — bioengineering — Posted on 2019-01-29

342 Water and ion transport across the eversible vesicles in the collophore of a springtail Orchesella cincta

Konopova, B.; Kolosov, D.; O'Donnell, M. J.

10.1101/534164 — physiology — Posted on 2019-01-29

343 Multicenter Analysis of Dosing Protocols for Sotalol Initiation

Biswas, M.; Levy, A. E.; Weber, R.; Tarakji, K.; Chung, M.; Noseworthy, P. A.; Newton-Cheh, C.; Rosenberg, M. A.

10.1101/531301 — pharmacology and toxicology — Posted on 2019-01-29

344 Bayesian Tip-dated Phylogenetics: Topological Effects, Stratigraphic Fit and the Early Evolution of Mammals

King, B.; Beck, R. M. D.

10.1101/533885 — paleontology — Posted on 2019-01-29

345 Characteristics of Beta Waveform Shape in Parkinson's Disease Detected with Scalp Electroencephalography

Jackson, N.; Cole, S. C.; Voytek, B.; Swann, N. C.

10.1101/534396 — neuroscience — Posted on 2019-01-29

346 Centromere-mediated chromosome break drives karyotype evolution in closely related Malassezia species

Sankaranarayanan, S. R.; Ianiri, G.; Reza, M. H.; Thimmappa, B. C.; Ganguly, P.; Coelho, M. A.; Sun, S.; Siddharthan, R.; Tellgren-Roth, C.; Dawson, T. L.; Heitman, J.; Sanyal, K.

10.1101/533794 — genomics — Posted on 2019-01-29

347 Spatial Regulation of Polo-like Kinase Activity during C. elegans Meiosis by the Nucleoplasmic HAL-2/HAL-3 Complex

Roelens, B.; Barroso, C.; Montoya, A.; Cutillas, P.; Zhang, W.; Woglar, A.; Girard, C.; Martinez-Perez, E.; Villeneuve, A.

10.1101/534339 — genetics — Posted on 2019-01-29

348 Controlling gene activation by enhancers through a drug-inducible topological insulator

Tsujimura, T.; Takase, O.; Yoshikawa, M.; Sano, E.; Hayashi, M.; Hoshi, K.; Takato, T.; Toyoda, A.; Okano, H.; Hishikawa, K.

10.1101/534073 — genetics — Posted on 2019-01-29

349 Signatures of recent positive selection in enhancers across 41 human tissues

Moon, J. M.; Capra, J. A.; Abbot, P.; Rokas, A.

10.1101/534461 — evolutionary biology — Posted on 2019-01-29

350 The determinants of genetic diversity in butterflies - Lewontin's paradox revisited

Mackintosh, A.; Laetsch, D. R.; Hayward, A.; Waterfall, M.; Vila, R.; Lohse, K.

10.1101/534123 — evolutionary biology — Posted on 2019-01-29

351 MTF1, a classic metal sensing transcription factor, promotes myogenesis in response to copper.

Tavera-Montanez, C.; Hainer, S. J.; Cangussu, D.; Gordon, S. J. V.; Xiao, Y.; Reyes-Gutierrez, P.; Imbalzano, A. N.; Navea, J. G.; Fazzio, T. G.; PADILLA-BENAVIDES, T.

10.1101/534271 — cell biology — Posted on 2019-01-29

352 Computational vaccinology approach: Designing an efficient multi-epitope peptide vaccine against Cryptococcus neoformans var. grubii heat shock 70KDa protein

Elhassan, R. M.; Alsony, N. M.; Othman, K. M.; Izz-Aldin, D. T.; Alhaj, T. A.; Ali, A. A.; Abashir, L. A.; Ahmed, O. H.; Hassan, M. A.

10.1101/534008 — bioinformatics — Posted on 2019-01-29

353 GAMer 2: A System for 3D Mesh Processing of Cellular Electron Micrographs

Lee, C. T.; Laughlin, J. G.; Angliviel de La Beaumelle, N.; Amaro, R.; McCammon, J. A.; Ramamoorthi, R.; Holst, M. J.; Rangamani, P.

10.1101/534479 — systems biology — Posted on 2019-01-29

354 DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute

Hegge, J. W.; Swarts, D. C.; Chandradoss, S. D.; Cui, T. J.; Kneppers, J.; Jinek, M.; Joo, C.; van der Oost, J.

10.1101/534206 — molecular biology — Posted on 2019-01-29

355 Emergent microscale gradients give rise to metabolic cross-feeding and antibiotic tolerance in clonal bacterial populations

Dal Co, A.; van Vliet, S.; Ackermann, M.

10.1101/534149 — microbiology — Posted on 2019-01-29

356 Genome-wide assessment of Mycobacterium tuberculosis conditionally essential metabolic pathways

Minato, Y.; Gohl, D. M.; Thiede, J. M.; Chacon, J. M.; Harcombe, W. R.; Maruyama, F.; Baughn, A. D.

10.1101/534289 — microbiology — Posted on 2019-01-29

357 Accumulation of Rare Coding Variants in Genes Implicated in Risk of Human Cleft Lip with or without Cleft Palate

Marini, N.; Asrani, K.; Yang, W.; Rine, J.; Shaw, G.

10.1101/533208 — genetics — Posted on 2019-01-29

358 Evolutionary Implications of Anoxygenic Phototrophy in the Bacterial Phylum Candidatus Palusbacterota (WPS-2)

Ward, L. M.; Cardona, T.; Holland-Moritz, H.

10.1101/534180 — evolutionary biology — Posted on 2019-01-29

359 HOPS: Automated detection and authentication of pathogen DNA in archaeological remains

Huebler, R.; Key, F. M. M.; Warinner, C.; Bos, K. I.; Krause, J.; Herbig, A.

10.1101/534198 — bioinformatics — Posted on 2019-01-29

360 Development of new food-sharing relationships among nonkin vampire bats

Carter, G. G.; Farine, D. R.; Crisp, R. J.; Vrtilek, J. K.; Ripperger, S.; Page, R.

10.1101/534321 — animal behavior and cognition — Posted on 2019-01-29

361 A GenoChemetic strategy for derivatization of the violacein natural product scaffold

Lai, H.-E.; Obled, A. M.; Chee, S. M.; Morgan, R. M.; Sharma, S. V.; Moore, S. J.; Polizzi, K. M.; Goss, R. J.; Freemont, P. S.

10.1101/202523 — synthetic biology — Posted on 2019-01-29

362 Pharmacological inhibition of GPR4 remediates intestinal inflammation in a mouse colitis model

Sanderlin, E. J.; Marie, M.; Velcicky, J.; Loetscher, P.; Yang, L. V.

10.1101/533174 — pharmacology and toxicology — Posted on 2019-01-29

363 Galton-Watson Process And Bayesian Inference: A Turnkey Method For The Viability Study Of Small Populations

Bertrand, C.; Daufresne, T.; Kerioui, M.; Fontez, B.

10.1101/530923 — ecology — Posted on 2019-01-29

364 Identifying and ranking potential driver genes of Alzheimer's Disease using multi-view evidence aggregation

Mukherjee, S.; Perumal, T.; Daily, K.; Sieberts, S.; Omberg, L.; Preuss, C.; Carter, G.; Mangravite, L.; Logsdon, B.

10.1101/534305 — bioinformatics — Posted on 2019-01-29

365 Gene sharing networks to automate genome-based prokaryotic viral taxonomy

Jang, H. B.; Bolduc, B.; Zablocki, O.; Kuhn, J.; Roux, S.; Adriaenssens, E.; Brister, J. R.; Kropinski, A.; Krupovic, M.; Turner, D.; Sullivan, M.

10.1101/533240 — bioinformatics — Posted on 2019-01-29

366 Reallocation to lateral and early-emerging axial roots allows maize (Zea mays L.) with reduced nodal root number to more efficiently forage for nitrate

Guo, H.; York, L. M.

10.1101/533042 — plant biology — Posted on 2019-01-29

367 Higher frequency of extra-pair offspring in urban than forest broods of great tits (Parus major)

Pipoly, I.; Szabo, K.; Bokony, V.; Preiszner, B.; Seress, G.; Vincze, E.; Schroeder, J.; Liker, A.

10.1101/526194 — ecology — Posted on 2019-01-29

368 Single-molecule long-read sequencing reveals the chromatin basis of gene expression

Wang, Y.; Wang, A.; Liu, Z.; Thurman, A.; Powers, L. S.; Zou, M.; Hefel, A.; Li, Y.; Zabner, J.; Au, K. F.

10.1101/533158 — bioinformatics — Posted on 2019-01-29

369 Is it time to change the reference genome?

Ballouz, S.; Dobin, A.; Gillis, J.

10.1101/533166 — genomics — Posted on 2019-01-29

370 Experimental design for large scale omic studies

Ogut, F.; Newman, J.; Bacher, R.; Concannon, P.; Verhoeven, K.; McIntyre, L.

10.1101/532580 — genetics — Posted on 2019-01-29

371 Distinct functional classes of excitatory neurons in mouse V1 are differentially modulated by learning and task engagement

Weskelblatt, J. B.; Niell, C. M.

10.1101/533463 — neuroscience — Posted on 2019-01-29

372 CAMITAX: Taxon labels for microbial genomes

Bremges, A.; Fritz, A.; McHardy, A. C.

10.1101/532473 — bioinformatics — Posted on 2019-01-29

373 Differential effects of open- and closed-loop intracortical microstimulation on firing patterns of neurons in distant cortical areas

Averna, A.; Pasquale, V.; Murphy, M.; Rogantin, M. P.; Van Acker, G.; Nudo, R.; Chiappalone, M.; Guggenmos, D.

10.1101/534032 — neuroscience — Posted on 2019-01-29

374 Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

Bernatchez, J. A.; Coste, M.; Beck, S.; Wells, G. A.; Luna, L. A.; Clark, A. E.; Zhu, Z.; Sohl, C. D.; Purse, B. W.; Siqueira-Neto, J. L.

10.1101/533497 — microbiology — Posted on 2019-01-29

375 Meta-analysis of massive parallel reporter assay enables functional regulatory elements prediction

Kreimer, A.; Yan, Z.; Ahituv, N.; Yosef, N.

10.1101/202002 — genomics — Posted on 2019-01-29

376 Genotypic frequencies at equilibrium for polysomic inheritance under double-reduction

Huang, K.; Wang, T.; Dunn, D. W.; Zhang, P.; Liu, R.; Cao, X.; Li, B.

10.1101/532861 — genetics — Posted on 2019-01-29

377 3D Ultrastructure of the Cochlear Outer Hair Cell Lateral Wall Revealed By Electron Tomography

Triffo, W.; Palsdottir, H.; Morgan, D. G.; MacDonald, K.; Raphael, R. M.; Auer, M.

10.1101/534222 — biophysics — Posted on 2019-01-29

378 Integrating multi-network topology for gene function prediction using deep neural networks

Xue, H.; Peng, J.; Shang, X.

10.1101/532408 — bioinformatics — Posted on 2019-01-29

379 Chemogenetic inhibition of the amygdala modulates emotional behavior expression in infant rhesus monkeys

Raper, J.; Murphy, L.; Richardson, R.; Romm, Z.; Kovacs-Balint, Z.; Payne, C.; Galvan, A.

10.1101/534214 — neuroscience — Posted on 2019-01-29

380 Complementary roles for ventral pallidum cell types and their projections in relapse

Prasad, A. A.; Xie, C.; Chaichim, C.; Killcross, S.; Power, J. M.; McNally, G. P.

10.1101/533554 — neuroscience — Posted on 2019-01-29

381 Interactions between cardiac activity and conscious somatosensory perception

Motyka, P.; Grund, M.; Forschack, N.; Al, E.; Villringer, A.; Gaebler, M.

10.1101/529636 — neuroscience — Posted on 2019-01-29

382 Comparative ChIP-seq (Comp-ChIP-seq): a practical guideline for experimental design and a novel computational methodology

Blanco, E.; Di Croce, L.; Aranda, S.

10.1101/532622 — genomics — Posted on 2019-01-29

383 Physicochemical Properties of Chromosomes in Live Cells Characterized by Label-Free Imaging and Fluorescence Correlation Spectroscopy

Kim, T.-K.; Lee, B.-W.; Fujii, F.; Lee, K.-H.; Park, Y.; Kim, J. K.; Pack, C.-G.

10.1101/533596 — biophysics — Posted on 2019-01-29

384 Process noise distinguishes between indistinguishable population dynamics

Simpson, M.; Ryan, J.; McGree, J.; Baker, R. E.

10.1101/533182 — synthetic biology — Posted on 2019-01-29

385 Identification of transgene-free CRISPR edited plants of rice and tomato by monitoring DsRED fluorescence in dry seeds

Aliaga Franco, N.; Zhang, C.; Presa, S.; Granell, A.; Alabadi, D.; Sadanandom, A.; Blazquez, M. A.; Minguet, E. G.

10.1101/533034 — plant biology — Posted on 2019-01-29

386 Magnetic Ultrathin Tissue Sections for Ease of Light and Electron Microscopy

Koestinger, G.; During, D.; Rickauer, S.; Leite, V.; Yamahachi, H.; Csucs, G.; Hahnloser, R. H.

10.1101/532549 — neuroscience — Posted on 2019-01-29

387 Defining tissue- and disease-associated macrophages using a transcriptome-based classification model

Chen, H.-J.; Li Yim, A. Y. F.; Griffith, G. R.; de Jonge, W. J.; Mannens, M. M. A. M.; Ferrero, E.; Henneman, P.; de Winther, M. P. J.

10.1101/532986 — immunology — Posted on 2019-01-29

388 Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Khandaker, G. M.; Zuber, V.; Rees, J. M.; Carvalho, L.; Mason, A. M.; Foley, C. N.; Gkatzionis, A.; Jones, P. B.; Burgess, S.

10.1101/533828 — genetics — Posted on 2019-01-29

389 Virome heterogeneity and connectivity in waterfowl and shorebird communities

Wille, M.; Shi, M.; Klaassen, M.; Hurt, A.; Holmes, E.

10.1101/528174 — ecology — Posted on 2019-01-29

390 G4-iM Grinder: DNA and RNA G-Quadruplex, i-Motif and higher order structure search and analyser tool

Belmonte Reche, E.; Morales, J. C.

10.1101/532382 — bioinformatics — Posted on 2019-01-29

391 Curated BLAST for Genomes

Price, M.; Arkin, A.

10.1101/533430 — bioinformatics — Posted on 2019-01-29

392 Dedifferentiation orchestrated through remodeling of the chromatin landscape defines PSEN1 mutation-induced Alzheimer's Disease

Caldwell, A. B.; Liu, Q.; Schroth, G. P.; Tanzi, R. E.; Galasko, D. R.; Yuan, S. H.; Wagner, S. L.; Subramaniam, S.

10.1101/531202 — neuroscience — Posted on 2019-01-29

393 The International Space Station selects for microorganisms adapted to the extreme environment, but does not induce genomic and physiological changes relevant for human health

Mora, M.; Wink, L.; Koegler, I.; Mahnert, A.; Rettberg, P.; Schwendner, P.; Demets, R.; Cockell, C.; Alekhova, T.; Klingl, A.; Alexandrova, A.; Moissl-Eichinger, C.

10.1101/533752 — microbiology — Posted on 2019-01-29

394 Deciphering tea tree chloroplast and mitochondrial genomes of Camellia sinensis var. assamica

Gao, L.; Zhang, F.; Li, W.; Gao, C.

10.1101/532853 — genomics — Posted on 2019-01-29

395 Using the structure of genome data in the design of deep neural networks for predicting amyotrophic lateral sclerosis from genotype

Yin, B.; Balvert, M.; van der Spek, R. A. A.; Dutilh, B. E.; Bohte, S.; Veldink, J.; Schoenhuth, A.

10.1101/533679 — genetics — Posted on 2019-01-29

396 The Piezo channel is used by migrating cells to sense compressive load

Srivastava, N.; Traynor, D.; Kabla, A.; Kay, R.

10.1101/534172 — biophysics — Posted on 2019-01-29

397 Harmonization and Annotation of Single-cell Transcriptomics data with Deep Generative Models

Xu, C.; Lopez, R.; Mehlman, E.; Regier, J.; Jordan, M. I.; Yosef, N.

10.1101/532895 — bioinformatics — Posted on 2019-01-29

398 Transfer of regulatory knowledge from human to mouse for functional genomic analysis

Holland, C. H.; Szalai, B.; Saez-Rodriguez, J.

10.1101/532739 — systems biology — Posted on 2019-01-29

399 Network based statistics reveals trophic and neuroprotective effect of early high dose erythropoetin on brain connectivity in very preterm infants

Jakab, A.; Ruegger, C.; Bucher, H. U.; Huppi, P.; Makki, M.; Tuura, R.; Hagmann, C.

10.1101/533901 — neuroscience — Posted on 2019-01-29

400 Translational regulation of non-autonomous mitochondrial stress response promotes longevity

Lan, J.; Rollins, J.; Wu, D.; Zang, X.; Zou, L.; Wang, Z.; Ye, C.; Wu, Z.; Kapahi, P.; Rogers, A. N.; Chen, D.

10.1101/533695 — developmental biology — Posted on 2019-01-29

401 Gene Info: Easy retrieval of gene product information on any website

Knight, J. D. R.; Samavarchi-Tehrani, P.; Gingras, A.-C.

10.1101/532523 — bioinformatics — Posted on 2019-01-29

402 A plant protein NbP3IP induces autophagy and mediates the autophagic degradation of RSV p3 to inhibit viral infection

Jiang, L. l.; Lu, Y. w.; Zheng, X.; Yang, X.; Chen, Y.; Zhang, T. h.; Zhao, X.; Wang, S.; Zhao, X.; Song, X. j.; Zhang, X. x.; Peng, J. j.; Zheng, H. y.; Lin, L.; MacFarlane, S.; Chen, J. p.; Liu, Y.; Yan, F.

10.1101/532275 — plant biology — Posted on 2019-01-29

403 Thioridazine as an Anticancer Therapeutic: Interplay with the Isoprenoid Biosynthetic Pathway

Weissenrieder, J. S.; Reed, J. L.; Neighbors, J. D.; Hohl, R. J.

10.1101/532788 — pharmacology and toxicology — Posted on 2019-01-29

404 Plant growth regulators interact with elevated temperature to alter heat stress signaling via the Unfolded Protein Response

Neill, E. M.; Byrd, M. C. R.; Billman, T.; Brandizzi, F.; Stapleton, A. E.

10.1101/532796 — plant biology — Posted on 2019-01-29

405 Heterogeneity in surface sensing produces a division of labor in Pseudomonas aeruginosa populations

Armbruster, C. R.; Lee, C. K.; Parker-Gilham, J.; de Anda, J.; Xia, A.; Tseng, B. S.; Hoffman, L. R.; Jin, F.; Harwood, C.; Wong, G. C. L.; Parsek, M. R.

10.1101/532598 — microbiology — Posted on 2019-01-29

406 Consecutive signaling pathways are activated in progression of Duchenne muscular dystrophy in C. elegans

Geissel, H.; Steber, H.; Newbern, J.; Rawls, A.; Mangone, M.

10.1101/532465 — genetics — Posted on 2019-01-29

407 A fruitful endeavor: scent cues and echolocation behavior used by Carollia castanea to find fruit

Leiser-Miller, L. B.; Kaliszewska, Z. A.; Lauterbur, M. E.; Mann, B.; Riffel, J. A.; Santana, S. E.

10.1101/532614 — ecology — Posted on 2019-01-29

408 How lucky was the genetic investigation in the Golden State Killer case?

Edge, M.; Coop, G.

10.1101/531384 — genomics — Posted on 2019-01-29

409 ABCDE approach to victims by lifeguards: how do they manage a critical patient? A cross sectional simulation study

Fernandez-Mendez, F.; Otero-Agra, M.; Abelairas-Gomez, C.; Saez-Gallego, N.; Rodriguez-Nunez, A.; Barcala-Furelos, R.

10.1101/533943 — physiology — Posted on 2019-01-29

410 Mating Induces Switch From Hormone-Dependent to -Independent Steroid Receptor-Mediated Growth in Drosophila Prostate-Like Cells

Wilson, C.; Leiblich, A.; Hellberg, J.; Sekar, A.; Gandy, C.; Redhai, S.; Wainwright, M.; Marie, P.; Goberdhan, D.; Hamdy, F.

10.1101/533976 — cell biology — Posted on 2019-01-29

411 SIMNETS: a computationally efficient and scalable framework for identifying sub-networks of functionally similar neurons

Hynes, J. B.; Brandman, D. M.; Zimmerman, J. B.; Donoghue, J. P.; Vargas-Irwin, C. E.

10.1101/463364 — neuroscience — Posted on 2019-01-29

412 Constitutively active RAS in S. pombe causes persistent Cdc42 signalling but only transient MAPK activation

Kelsall, E. J.; Vertesy, A.; Straatman, K.; Tariq, M.; Gadea, R.; Parmar, C.; Schreiber, G.; Randhawa, S.; Dominguez, C.; Klipp, E.; Tanaka, K.

10.1101/380220 — molecular biology — Posted on 2019-01-29

413 Nothing else matters? Tree characteristics have more effects than biogeoclimatic context on microhabitat diversity and occurrence: a nationwide analysis.

Paillet, Y.; Debaive, N.; Archaux, F.; Cateau, E.; Gilg, O.; Guilbert, E.

10.1101/335836 — ecology — Posted on 2019-01-29

414 The metastable XBP1u transmembrane domain defines determinants for intramembrane proteolysis by signal peptide peptidase

Yucel, S. S.; Stelzer, W.; Lorenzoni, A.; Wozny, M.; Langosch, D.; Lemberg, M. K.

10.1101/322107 — cell biology — Posted on 2019-01-29

415 Emergence and suppression of cooperation by action visibility in transparent games

Unakafov, A. M.; Schultze, T.; Kagan, I.; Moeller, S.; Eule, S.; Wolf, F.

10.1101/314500 — evolutionary biology — Posted on 2019-01-29

416 Neural correlates of learning pure tones versus natural sounds in the auditory cortex

Maor, I.; Shwartz-Ziv, R.; Feigin, L.; Elyada, Y.; Sompolinsky, H.; Mizrahi, A.

10.1101/273342 — neuroscience — Posted on 2019-01-29

417 The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

Pervolaraki, E.; Tyson, A. L.; Pibiri, F.; Poulter, S. L.; Reichelt, A. C.; Rodgers, R. J.; Clapcote, S. J.; Lever, C.; Andreae, L. C.; Dachtler, J.

10.1101/300806 — neuroscience — Posted on 2019-01-29

418 DNA methylation and histone H1 cooperatively repress transposable elements and aberrant intragenic transcripts

Choi, J.; Lyons, D. B.; Kim, Y.; Moore, J. D.; Zilberman, D.

10.1101/527523 — genetics — Posted on 2019-01-29

419 Accounting for individual-specific variation in habitat-selection studies: Efficient estimation of mixed-effects models using Bayesian or frequentist computation

Muff, S.; Signer, J.; Fieberg, J.

10.1101/411801 — ecology — Posted on 2019-01-29

420 Biological Sequence Modeling with Convolutional Kernel Networks

Chen, D.; Jacob, L.; Mairal, J.

10.1101/217257 — bioinformatics — Posted on 2019-01-29

421 Impoverished auditory cues fail to engage brain networks controlling spatial selective attention

Deng, Y.; Choi, I.; Shinn-Cunningham, B. G.; Baumgartner, R.

10.1101/533117 — neuroscience — Posted on 2019-01-29

422 Tubulin as a sensitive target of nanosecond-scale intense electric field: quantitative insights from molecular dynamics simulations

Marracino, P.; Havelka, D.; Prusa, J.; Liberti, M.; Tuszynski, J. A.; Ayoub, A. T.; Apollonio, F.; Cifra, M.

10.1101/533984 — biophysics — Posted on 2019-01-29

423 Community-based Sero-prevalence of Hepatitis B and C Infections in South Omo Zone, Southern Ethiopia

WOLDEGIORGIS, A. E.; Erku, W.; Medhin, G.; Berhe, N.; Legesse, M.

10.1101/533968 — epidemiology — Posted on 2019-01-29

424 Effects of Lactobacillus plantarum 15-1 and fructooligosaccharide on the response of broilers to pathogenic Escherichia coli O78 challenge

Ding, S.; Wang, Y.; Yan, W.; Li, A.; Jiang, H.; Fang, J.

10.1101/533935 — zoology — Posted on 2019-01-29

425 Maximum Parsimony Interpretation of Chromatin Capture Experiments

Homouz, D.; Kudlicki, A. S.

10.1101/533992 — genomics — Posted on 2019-01-29

426 Effectiveness of a mobile antiretroviral pharmacy and HIV care intervention on the continuum of HIV care in rural Uganda

Bajunirwe, F.; Ayebazibwe, N.; Mulogo, E.; Eng, M.; McGrath, J.; Kaawa-Mafigiri, D.; Mugyenyi, P.; Sethi, A. K.

10.1101/533950 — epidemiology — Posted on 2019-01-29

427 k-BOOM: A Bayesian approach to ontology structure inference, with applications in disease ontology construction

Mungall, C. J.; Koehler, S.; Robinson, P.; Holmes, I.; Haendel, M.

10.1101/048843 — bioinformatics — Posted on 2019-01-29

428 Evaluating potential drug targets through human loss-of-function genetic variation

Minikel, E. V.; Karczewski, K. J.; Martin, H. C.; Cummings, B. B.; Whiffin, N.; Alfoldi, J.; Trembath, R. C.; van Heel, D. A.; Daly, M. J.; Genome Aggregation Database Production Team, ; Genome Aggregation Database Consortium, ; Schreiber, S. L.; MacArthur, D. G.

10.1101/530881 — genomics — Posted on 2019-01-29

429 DNA double-strand breaks induced by reactive oxygenspecies promote DNA polymerase IV activity in Escherichia coli

Henrikus, S. S.; Henry, C.; McDonald, J. P.; Hellmich, Y.; Wood, E. A.; Woodgate, R.; Cox, M. M.; van Oijen, A. M.; Ghodke, H.; Robinson, A.

10.1101/533422 — molecular biology — Posted on 2019-01-29

430 High-speed device synchronization in optical microscopy with an open-source hardware control platform

Colville, M. J.; Park, S.; Zipfel, W. R.; Paszek, M. J.

10.1101/533349 — biophysics — Posted on 2019-01-29

431 N-terminal 45 amino acids of DEF6 are necessary and sufficient to spontaneously colocalise with DCP1 in P-bodies

Cheng, H.; Alsayegh, M.; Sablitzky, F.

10.1101/533109 — molecular biology — Posted on 2019-01-29

432 CADHERIN-11 BLOCKADE REDUCES INFLAMMATION DRIVEN FIBROTIC REMODELING AND IMPROVES OUTCOMES AFTER MYOCARDIAL INFARCTION

Schroer, A.; Bersi, M.; Clark, C.; Zhang, Q.; Sanders, L.; Hatzopoulos, A.; Force, T.; Majka, S.; Lal, H.; Merryman, W. D.

10.1101/533000 — molecular biology — Posted on 2019-01-29

433 Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells.

Alharbi, Y. M.; Kapur, A.; Felder, M. S.; Barroilhet, L. S.; Stein, T.; Pattnaik, B.; Patankar, M. S.

10.1101/532812 — cancer biology — Posted on 2019-01-29

434 Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13

Liu, Z.; Dong, X.; Yi, H.-W.; Yang, J.; Gong, Z.; Wang, Y.; Liu, K.; Zhang, W.-P.; Tang, C.

10.1101/533331 — biophysics — Posted on 2019-01-29

435 Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues

Gasic, I.; Boswell, S. A.; Mitchison, T. J.

10.1101/533224 — cell biology — Posted on 2019-01-29

436 IRE1-UBE2D3 signaling controls the recruitment of myeloid cells to glioblastoma.

chevet, e.; Obacz, J.; Archambeau, J.; Le Reste, P. J.; Pineau, R.; Jouan, F.; Barroso, K.; Vlachavas, E.; Voutetakis, K.; Fainsod-Levi, T.; Obiedat, A.; Granot, Z.; Tirosh, B.; Samal, J.; Pandit, A.; Patterson, J.; Zheng, Q.; Negroni, L.; Chatziioannou, A.; Quillien, V.; Avril, T.

10.1101/533018 — cancer biology — Posted on 2019-01-29

437 A Minimal Self-Organization model of the Golgi Apparatus

Vagne, Q.; Vrel, J.-P.; Sens, P.

10.1101/532556 — biophysics — Posted on 2019-01-29

438 DeepTRIAGE: Interpretable and Individualised BiomarkerScores using Attention Mechanism for the Classification of Breast Cancer Sub-types

Beykikhoshk, A.; Quinn, T. P.; Lee, S. C.; Tran, T.; Venkatesh, S.

10.1101/533406 — biophysics — Posted on 2019-01-29

439 Phosphatidylinositol 3,5-Bisphosphate regulates Ca2+ Transport During Yeast Vacuolar Fusion through Activation of the Ca2+ ATPase Pmc1

Fratti, R. A.; Miner, G. E.; Sullivan, K. D.; Guo, A.; Starr, M. L.; Ellis, E.; Jones, B.

10.1101/533067 — biochemistry — Posted on 2019-01-29

440 Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency

Garcia-Tunon, I.; Alonso-Perez, V.; Vuelta, E.; Perez- Ramos, S.; Herrero, M.; Mendez, L.; Hernandez-Sanchez, J. M.; Martin-Izquierdo, M.; Saldana, R.; Sevilla, J.; Sanchez-Guijo, F.; Hernandez-Rivas, J. M.; Sanchez-Martin, M. A.

10.1101/532820 — molecular biology — Posted on 2019-01-29

441 The SUMO ligase Su(var)2-10 links piRNA-guided target recognition to chromatin silencing

Ninova, M.; Chen, Y.-C. A.; Godneeva, B.; Rogers, A. K.; Luo, Y.; Aravin, A. A.; Fejes Toth, K.

10.1101/533091 — molecular biology — Posted on 2019-01-29

442 The SUMO ligase Su(var)2-10 controls eu- and heterochromatic gene expression via establishment of H3K9 trimethylation and negative feedback regulation

Ninova, M.; Godneeva, B.; Chen, Y.-C. A.; Luo, Y.; Prakash, S. J.; Jankovics, F.; Erdelyi, M.; Fejes Toth, K.; Aravin, A. A.

10.1101/533232 — molecular biology — Posted on 2019-01-29

443 Intra-bin structural variant segmentation for whole-genome sequencing data using U-net

Zhang, Y.-z.; Imoto, S.; Miyano, S.; Yamaguchi, R.

10.1101/503649 — bioinformatics — Posted on 2019-01-28

444 Centering based on active diffusion in mouse oocytes is non-specific

Colin, A.; Ratzin, N.; Almonacid, M.; Ahmed, W.; Betz, T.; Terret, M.-E.; Gov, N.; Voituriez, R.; Gueroui, Z.; VERLHAC, M.-H.

10.1101/531657 — cell biology — Posted on 2019-01-28

445 Sex Differences in Oncogenic Mutational Processes

Li, C. H.; Prokopec, S. D.; Sun, R. X.; Yousif, F.; Schmitz, N.; Boutros, P. C.; PCAWG Molecular Subtypes and Clinical Correlates Working Group, ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network,

10.1101/528968 — cancer biology — Posted on 2019-01-28

446 Inter-individual Variability of Functional Connectivity in Awake and Anesthetized Rhesus Monkeys

Xu, T.; Sturgeon, D.; Ramirez, J. S. B.; Froudist-Walsh, S.; Margulies, D. S.; Schroeder, C. E.; Fair, D. A.; Milham, M.

10.1101/531293 — neuroscience — Posted on 2019-01-28

447 Neurocomputational mechanisms underlying motivated seeing

Leong, Y. C.; Hughes, B. L.; Wang, Y.; Zaki, J.

10.1101/364836 — neuroscience — Posted on 2019-01-28

448 Commonly used insect repellents hide human odors from Anopheles mosquitoes

Afify, A.; Betz, J. F.; Riabinina, O.; Potter, C. J.

10.1101/530964 — neuroscience — Posted on 2019-01-28

449 The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membrane-less granular phase-separation

Lyonnais, S.; Sadiq, S. K.; Lorca-Oro, C.; Dufau, L.; Nieto-Marquez, S.; Escriba, T.; Gabrielli, N.; Tan, X.; Ouizougun-Oubari, M.; Okoronkwo, J.; Reboud-Ravaux, M.; Gatell, J. M.; Marquet, R.; Paillart, J.-C.; Meyerhans, A.; Tisne, C.; Gorelick, R. J.; Mirambeau, G.

10.1101/528638 — molecular biology — Posted on 2019-01-28

450 Comammox bacteria are dominant ammonia oxidizers in rotating biological contactors of a municipal wastewater treatment plant

Spasov, E.; Tsuji, J. M.; Hug, L. A.; Doxey, A. C.; Sauder, L. A.; Parker, W. J.; Neufeld, J. D.

10.1101/529826 — microbiology — Posted on 2019-01-28

451 Exploiting selection at linked sites to infer the rate and strength of adaptation

Uricchio, L. H.; Petrov, D. A.; Enard, D.

10.1101/427633 — evolutionary biology — Posted on 2019-01-28

452 The Minimum Environmental Perturbation Principle: A New Perspective on Niche Theory

Marsland, R.; Cui, W.; Mehta, P.

10.1101/531640 — ecology — Posted on 2019-01-28

453 Flexible pivoting of the pleckstrin homology domain in dynamin catalyzes fission by affecting membrane properties: Insights into the molecular degrees of freedom

Jha, K.; Baratam, K.; Dubey, V.; Pucadyil, T.; Srivastava, A.

10.1101/531814 — biophysics — Posted on 2019-01-28

454 Mechanistic interpretation of non-coding variants helps discover transcriptional regulators of drug response

Xie, X.; Hanson, C.; Sinha, S.

10.1101/503458 — bioinformatics — Posted on 2019-01-28

455 Social tolerance in Octopus laqueus - a maximal entropy model

Edsinger, E.; Pnini, R.; Ono, N.; Yanagisawa, R.; Dever, K.; Miller, J.

10.1101/526905 — animal behavior and cognition — Posted on 2019-01-28

456 Skyhawk: An Artificial Neural Network-based discriminator for reviewing clinically significant genomic variants

Luo, R.; Lam, T.-W.; Schatz, M.

10.1101/311985 — bioinformatics — Posted on 2019-01-28

457 The Project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public

van der Spek, R. A. A.; van Rheenen, W.; Pulit, S. L.; Kenna, K. P.; McLaughlin, R. L.; Moisse, M.; Dekker, A. M.; Tazelaar, G. H. P.; Kenna, B.; van Eijk, K. R.; van Vugt, J. J. F. A.; van Doormaal, P. T. C.; Middelkoop, B.; Schellevis, R. D.; Brands, W. J.; Byrne, R.; Cooper-Knock, J.; Al Khleifat, A.; Campos, Y.; Vural, A.; Glass, J. D.; Iacoangeli, A.; Shatunov, A.; Sproviero, W.; Kavak, E.; Seker, T.; Akcimen, F.; Kocoglu, C.; Tunca, C.; Ticozzi, N.; Kooyman, M.; Redondo, A. G.; Blair, I.; Wray, N. R.; Kiernan, M. C.; de Carvalho, M.; Drory, V.; Gotkine, M.; Andersen, P. M.; Corcia, P.; C

10.1101/377911 — genomics — Posted on 2019-01-28

458 Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes

De Maio, N.; Shaw, L. P.; Hubbard, A.; George, S.; Sanderson, N.; Swann, J.; Wick, R.; AbuOun, M.; Stubberfield, E.; Hoosdally, S. J.; Crook, D. W.; Peto, T. E. A.; Sheppard, A. E.; Bailey, M. J.; Read, D. S.; Anjum, M. F.; Walker, A. S.; Stoesser, N.; The REHAB consortium,

10.1101/530824 — bioinformatics — Posted on 2019-01-28

459 Genomes of a major nosocomial pathogen Enterococcus faecium are shaped by adaptive evolution of the chromosome and plasmidome

Arredondo-Alonso, S.; Top, J.; Schürch, A. C.; McNally, A.; Puranen, S.; Pesonen, M.; Pensar, J.; Marttinen, P.; Braat, J. C.; Rogers, M. R.; van Schaik, W.; Kaski, S.; Corander, J.; Willems, R. J.

10.1101/530725 — genomics — Posted on 2019-01-28

460 Cytokinetic furrowing and abscission dynamics during brain development revealed by live imaging

McNeely, K. C.; Little, J. N.; Dwyer, N. D.

10.1101/529164 — developmental biology — Posted on 2019-01-28

461 Translationally Controlled Tumor Protein TCTP as Peptide Vaccine against Schistosoma japonicum: an Immunoinformatics Approach

Abdalrahman, R. A.; Ahmed, S. S.; Elnaeem, M. A.; Mohammed, M. S.; Jammie, N. M.; Yousif, I. A.; Mohamed, W. H.; Nasr, S. Y.; Awad-Elkareem, M. A.; Hassan, M. A.

10.1101/466847 — bioinformatics — Posted on 2019-01-28

462 Myocardin ablation in a cardiac-renal rat model

Mittal, A.; Rana, S.; Sharma, R.; Kumar, A.; Prasad, R.; Raut, S. K.; Sarkar, S.; Nahar, U.; Bahl, A.; Dhandapany, P. S.; Khullar, M.

10.1101/470708 — molecular biology — Posted on 2019-01-28

463 Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, L. R.; Zeng, J.; Sidorenko, J.; Yengo, L.; Moser, G.; Kemper, K. E.; Wang, H.; Zheng, Z.; Magi, R.; Esko, T.; Metspalu, A.; Wray, N. R.; Goddard, M. E.; Yang, J.; Visscher, P. M.

10.1101/522961 — genetics — Posted on 2019-01-28

464 The quiescent X, the replicative Y and the Autosomes

Achaz, G.; Gangloff, S.; Arcangioli, B.

10.1101/351288 — evolutionary biology — Posted on 2019-01-28

465 Prediction of Algal Blooms in the Great Lakes through a Convolution Neural Network of Remote Sensing Data

Srinivasan, K.; Duvvur, V.; Hess, D.

10.1101/450551 — ecology — Posted on 2019-01-28

466 The effects of a TMS double lesion to a cortical network

Cameron, I.; Cretu, A.; Struik, F.; Toni, I.

10.1101/517128 — neuroscience — Posted on 2019-01-28

467 Orientation-selective adaptation improves perceptual grouping

Pinchuk-Yacobi, N.; Sagi, D.

10.1101/519561 — neuroscience — Posted on 2019-01-28

468 Conduit integrity is compromised during acute lymph node expansion

Martinez, V. G.; Pankova, V.; Krasny, L.; Singh, T.; White, I. J.; Benjamin, A. C.; Dertschnig, S.; Horsnell, H. L.; Kristin-Vizi, J.; Burden, J. J.; Huang, P. H.; Tape, C. J.; Acton, S. E.

10.1101/527481 — immunology — Posted on 2019-01-28

469 Glial response to hypoxia in trachealess mutants induces synapse remodeling.

Chen, P.-Y.; Tsai, Y.-W.; Giangrande, A.; Chien, C.-T.

10.1101/527671 — genetics — Posted on 2019-01-28

470 Is it impossible to acquire absolute pitch in adulthood?

Wong, Y. K.; Lui, K. F. H.; Yip, K. H. M.; Wong, A. C.- N.

10.1101/355933 — animal behavior and cognition — Posted on 2019-01-28

471 Determining targeting specificity of nuclear-encoded organelle proteins with the self-assembling split fluorescent protein toolkit

Sharma, M.; Kretschmer, C.; Lampe, C.; Stuttmann, J.; Klosgen, R. B.

10.1101/480962 — plant biology — Posted on 2019-01-28

472 Metabolic potential of uncultured bacteria and archaea associated with petroleum seepage in deep-sea sediments

DONG, X.; Greening, C.; Rattray, J. E.; Chakraborty, A.; Chuvochina, M.; Mayumi, D.; Dolfing, J.; Li, C.; Brooks, J. M.; Bernard, B. B.; Groves, R. A.; Lewis, I. A.; Hubert, C. R. J.

10.1101/400804 — microbiology — Posted on 2019-01-28

473 Platelet-neutrophil aggregates promote skin pathology in psoriasis

Herster, F.; Bittner, Z.; Codrea, M. C.; Archer, N.; Heister, M.; Loeffler, M. W.; Heumos, S.; Wegner, J.; Businger, R.; Schindler, M.; Stegner, D.; Schaekel, K.; Grabbe, S.; Ghoreschi, K.; Miller, L.; Weber, A. N. R.

10.1101/526236 — immunology — Posted on 2019-01-28

474 Enteropathogen seroepidemiology among children in low-resource settings

Arnold, B. F.; Martin, D. L.; Juma, J.; Mkocha, H.; Ochieng, J. B.; Cooley, G. M.; Omore, R.; Goodhew, E. B.; Morris, J. F.; Costantini, V.; Vinje, J.; Lammie, P. J.; Priest, J. W.

10.1101/522920 — epidemiology — Posted on 2019-01-28

475 Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy

Ross, J. A.; Levy, Y.; Ripolone, M.; Kolb, J. S.; Turmaine, M.; Holt, M.; Moggio, M.; Fiorillo, C.; Lindqvist, J.; Figeac, N.; Zammit, P.; Jungbluth, H.; Vissing, J.; Witting, N.; Granzier, H.; Zanoteli, E.; Hardeman, E. C.; Wallgren-Pettersson, C.; Ochala, J.

10.1101/518522 — cell biology — Posted on 2019-01-28

476 Pancreatic tumor organoids for modeling in vivo drug response and discovering clinically-actionable biomarkers

huang, l.; Bockorny, B.; Paul, I.; Akshinthala, D.; Gandarilla, O.; Bose, A.; Sanchez-Gonzalez, V.; Rouse, E.; Lehoux, S.; Pandell, N.; Clohessy, J.; Grossman, J.; Gonzalez, R.; Perea del Pino, S.; Daaboul, G.; Sawhney, M.; Freedman, S.; Cummings, R.; Emili, A.; Muthuswamy, L.; Hidalgo, M.; Muthuswamy, S.

10.1101/513267 — cancer biology — Posted on 2019-01-28

477 A hierarchical watershed model of fluid intelligence in childhood and adolescence

Fuhrmann, D.; Simpson-Kent, I. L.; Bathelt, J.; the CALM team, ; Kievit, R. A.

10.1101/435719 — neuroscience — Posted on 2019-01-28

478 Constrained mutational sampling of amino acids in HIV-1 protease evolution

Boucher, J. I.; Whitfield, T. W.; Dauphin, A.; Nauchum, G.; Zeldovich, K. B.; Swanstrom, R.; Schiffer, C. A.; Luban, J.; Bolon, D. N. A.

10.1101/354597 — evolutionary biology — Posted on 2019-01-28

479 Assessment of Menstrual Health Status and Evolution through Mobile Apps for Fertility Awareness

Symul, L.; Wac, K.; Hillard, P.; Salathe, M.

10.1101/385054 — epidemiology — Posted on 2019-01-28

480 A deep learning approach to pattern recognition for short DNA sequences

Busia, A.; Dahl, G. E.; Fannjiang, C.; Alexander, D. H.; Dorfman, E.; Poplin, R.; McLean, C. Y.; Chang, P.-C.; DePristo, M.

10.1101/353474 — bioinformatics — Posted on 2019-01-28

481 Phenotypic, functional and taxonomic features predict host-pathogen interactions

Liu-Wei, W.; Kafkas, S.; Hoehndorf, R.

10.1101/508762 — bioinformatics — Posted on 2019-01-28

482 From Synchrony to Asynchrony: Cerebellar-Basal Ganglia Functional Circuits in Young and Older Adults

Hausman, H. K.; Jackson, T. B.; Goen, J. R.; Bernard, J.

10.1101/309344 — neuroscience — Posted on 2019-01-28

483 Antibiotic inhibition of bacteria growth in droplets reveals heteroresistance pattern at the single cell level

Scheler, O.; Makuch, K.; Debski, P. R.; Horka, M.; Ruszczak, A.; Pacocha, N.; Sozanski, K.; Smolander, O.-P.; Postek, W.; Garstecki, P.

10.1101/328393 — microbiology — Posted on 2019-01-28

484 RNA-antimicrobial peptide LL-37 complexes activate a self-sustaining TLR- and NET-mediated cycle of neutrophil activation

Herster, F.; Bittner, Z.; Dickhoefer, S.; Eisel, D.; Eigenbrod, T.; Knorpp, T.; Schneiderhan-Marra, N.; Loeffler, M. W.; Kalbacher, H.; Hartl, D.; Freund, L.; Schaekel, K.; Heiser, M.; Ghoreschi, K.; Weber, A. N. R.

10.1101/324814 — immunology — Posted on 2019-01-28

485 PDE5 inhibition improves symptom-free survival and restores transverse tubule loss and catecholamine responsiveness in heart failure

Lawless, M.; Caldwell, J. L.; Smith, C. E. R.; Radcliffe, E. J.; Madders, G. W.; Huthchings, D. C.; Woods, L. S.; Church, S. J.; Unwin, R. D.; Kirkwood, G. J.; Becker, L. K.; Pearman, C. M.; Taylor, R. F.; Eisner, D. A.; Dibb, K. M.; Trafford, A. W.

10.1101/248187 — physiology — Posted on 2019-01-28

486 Necrotizing Soft-Tissue Infections-Staphylococcus aureus -but not Streptococcus pyogenes- isolates display high rate of internalization and cytotoxicity toward human myoblasts

Baude, J.; Bastien, S.; GILLET, Y.; Leblanc, P.; Itzek, A.; Tristan, A.; Bes, M.; Duguez, S.; Moreau, K.; Diep, B. A.; Norrby-Teglund, A.; Henry, T.; Vandenesch, F.

10.1101/530493 — molecular biology — Posted on 2019-01-28

487 RE-EVALUATION OF MEFV GENE VARIANTS: UTILITY OF A GENE SPECIFIC THRESHOLD IN REDUCING THE NUMBER OF VARIANTS OF UNKNOWN SIGNIFICANCE

Accetturo, M.; DUggento, A. M.; Portincasa, P.; Stella, A.

10.1101/532804 — bioinformatics — Posted on 2019-01-28

488 CoPhosK: A Method for Comprehensive Kinase Substrate Annotation Using Co-phosphorylation Analysis

Ayati, M.; Wiredja, D.; Schlatzer, D.; Maxwell, S.; Li, M.; Koyuturk, M.; Chance, M.

10.1101/251009 — bioinformatics — Posted on 2019-01-28

489 Stability of dynamic functional architecture differs between brain networks and states

Li, L.; Lu, B.; Yan, C.-G.

10.1101/533307 — neuroscience — Posted on 2019-01-28

490 Dynamic CRMP2 regulation of CaV2.2 in the prefrontal cortex contributes to the reinstatementof cocaine seeking

Buchta, W. C.; Moutal, A.; Hines, B.; Garcia-Keller, C.; Smith, A. C. W.; Kalivas, P.; Khanna, R.; Riegel, A.

10.1101/533083 — neuroscience — Posted on 2019-01-28

491 Cost of preterm birth during initial hospitalization: A care providers perspective

Zainal, H.; Dahlui, M.; Soelar, S. A.; Su, T. T.

10.1101/532713 — epidemiology — Posted on 2019-01-28

492 Sequence-dependent trafficking of GDE2, a GPI-specific phospholipase promoting neuronal differentiation

Salgado-Polo, F.; van Veen, M.; van den Broek, B.; Leyton Puig, D.; Baas, R.; Perrakis, A.; Moolenaar, W. H.; Matas-Rico, E.

10.1101/532499 — neuroscience — Posted on 2019-01-28

493 Extinction-resistant attention to long-term conditioned threat is indexed by selective visuocortical alpha suppression in humans

Panitz, C.; Keil, A.; Mueller, E. M.

10.1101/533141 — neuroscience — Posted on 2019-01-28

494 Financial implications of preterm birth during initial hospitalization: The extent and predictors of catastrophic health expenditure

Zainal, H.; Dahlui, M.; Su, T. T.

10.1101/532697 — epidemiology — Posted on 2019-01-28

495 Molecular Dynamics Simulations of the Interaction of Mouse and Torpedo Acetylcholinesterase with Covalent Inhibitors Explain Their Differential Reactivity: Implications for Drug Design

Chandar, N. B.; Efremenko, I.; Silman, I.; Martin, J. M. L.; Sussman, J. L.

10.1101/532754 — biophysics — Posted on 2019-01-28

496 Spatio-temporal structure of single neuron subthalamic activity in Tourette Syndrome explored during DBS procedures

Vissani, M.; Cordella, R.; Micera, S.; Romito, L. M.; Mazzoni, A.

10.1101/532200 — neuroscience — Posted on 2019-01-28

497 Perturbations of a Kinase-Pseudokinase Module Activate Plant Immunity

Bastedo, D. P. P.; Seto, D.; Martel, A.; Khan, M.; Kireeva, I.; Zhang, J.; Masud, W.; Millar, D.; Lee, J. Y.; Lee, A. H.-Y.; Gong, Y.; Santos-Severino, A.; Guttman, D. S.; Desveaux, D.

10.1101/531665 — molecular biology — Posted on 2019-01-28

498 Accelerating surveillance and research of antimicrobial resistance - an online repository for sharing of antimicrobial susceptibility data associated with whole genome sequences

Matamoros, S.; Hendriksen, R.; Pataki, B.; Pakseresht, N.; Rossello, M.; Silvester, N.; Amid, C.; COMPARE ML-AMR group, ; Cochrane, G.; Csabai, I.; Lund, O.; Schultsz, C.

10.1101/532267 — microbiology — Posted on 2019-01-28

499 Yorkie controls tube length and apical barrier integrity in the developing Drosophila airways

Papadopoulos, D. K.; Tomancak, P.; Tsarouhas, V.; Samakovlis, C.; Knust, E.; Skouloudaki, K.

10.1101/532325 — developmental biology — Posted on 2019-01-28

500 catch22: CAnonical Time-series CHaracteristics

Lubba, C. H.; Sethi, S. S.; Knaute, P.; Schultz, S. R.; Fulcher, B. D.; Jones, N. S.

10.1101/532259 — bioinformatics — Posted on 2019-01-28

501 VarSight: Prioritizing Clinically Reported Variants with Binary Classification Algorithms

Holt, J. M.; Wilk, B.; Birch, C. L.; Brown, D. M.; Gajapathy, M.; Moss, A. C.; Sosonkina, N.; Wilk, M. A.; Anderson, J. A.; Harris, J. M.; Kelly, J. M.; Shaterferdosian, F.; Uno-Antonison, A. E.; Weborg, A.; Undiagnosed Diseases Network, ; Worthey, E. A.

10.1101/532440 — bioinformatics — Posted on 2019-01-28

502 Visual imagery and visual perception induce similar changes in occipital slow waves of sleep

Bernardi, G.; Betta, M.; Cataldi, J.; Leo, A.; Haba-Rubio, J.; Heinzer, R.; Cirelli, C.; Tononi, G.; Pietrini, P.; Ricciardi, E.; Siclari, F.

10.1101/532317 — neuroscience — Posted on 2019-01-28

503 Prevalence of near-death experiences and REM sleep intrusion in 1034 adults from 35 countries

Kondziella, D.; Olsen, M. H.

10.1101/532341 — neuroscience — Posted on 2019-01-28

504 Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer.

Guerrero Llobet, S.; van der Vegt, B.; Jongeneel, E.; Bense, R.; Schroder, C.; Everts, M.; de Bock, G.; van Vugt, M.

10.1101/532283 — cancer biology — Posted on 2019-01-28

505 Impact and evolutionary determinants of Neanderthal introgression on transcriptional and post-transcriptional regulation

Silvert, M.; Quintana-Murci, L.; Rotival, M.

10.1101/532366 — evolutionary biology — Posted on 2019-01-28

506 Phytoremediation of heavy metals in spent engine oil-polluted soil by Senna alata L.

Ugwu, E. C.; Nwadinigwe, A. O.; Agbo, B. C.

10.1101/532887 — ecology — Posted on 2019-01-28

507 Structural basis of glycerophosphodiester recognition by the Mycobacterium tuberculosis substrate-binding protein UgpB

Fenn, J.; Nepravishta, R.; Guy, C. S.; Harrison, J.; Angulo, J.; Cameron, A. D.; Fullam, E.

10.1101/529602 — biochemistry — Posted on 2019-01-28

508 Facilitating open-science with realistic fMRI simulation: validation and application

Ellis, C.; Baldassano, C.; Schapiro, A. C.; Cai, M. B.; Cohen, J.

10.1101/532424 — neuroscience — Posted on 2019-01-28

509 Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits

Zhang, W.; Voloudakis, G.; Rajagopal, V. M.; Reahead, B.; Dudley, J. T.; Schadt, E. E.; Bjorkegren, J. L.; Kim, Y.; Fullard, J. F.; Hoffman, G. E.; Roussos, P.

10.1101/532929 — genetics — Posted on 2019-01-28

510 The molecular clock of Mycobacterium tuberculosis

Menardo, F.; Duchene, S.; Brites, D.; Gagneux, S.

10.1101/532390 — evolutionary biology — Posted on 2019-01-28

511 How many cubs can a mum raise? Maternal age and size influence litter size in polar bears

Folio, D. M.; Aars, J.; Gimenez, O.; Derocher, A. E.; Wiig, O.; Cubaynes, S.

10.1101/532945 — ecology — Posted on 2019-01-28

512 Inhibiting IFT dynein with ciliobrevin in C. elegans chemosensory cilia

Mijalkovic, J.; Peterman, E.

10.1101/531848 — biophysics — Posted on 2019-01-28

513 A causal inference framework for estimating genetic variance and pleiotropy from GWAS summary data

Park, Y.; He, L.; Kellis, M.

10.1101/531673 — bioinformatics — Posted on 2019-01-28

514 Block HSIC Lasso: model-free biomarker detection for ultra-high dimensional data

Climente-Gonzalez, H.; Azencott, C.-A.; Kaski, S.; Yamada, M.

10.1101/532192 — bioinformatics — Posted on 2019-01-28

515 Geometric probability, psychophysics and invariance

Hart, Y.; Mahadevan, L.

10.1101/531889 — neuroscience — Posted on 2019-01-28

516 Regular cycling between representations of alternatives in the hippocampus

Kay, K.; Chung, J. E.; Sosa, M.; Schor, J. S.; Karlsson, M. P.; Larkin, M. C.; Liu, D. F.; Frank, L. M.

10.1101/528976 — neuroscience — Posted on 2019-01-28

517 Individual tree-crown detection in RGB imagery using self-supervised deep learning neural networks

Weinstein, B.; Marconi, S.; Bohlman, S.; Zare, A.; White, E.

10.1101/532952 — ecology — Posted on 2019-01-28

518 Applying stochastic spike train theory for high-accuracy MEG/EEG

Haumann, N. T.; Huotilainen, M.; Vuust, P.; Brattico, E.

10.1101/532879 — neuroscience — Posted on 2019-01-28

519 Neuroinflammation and functional connectivity in Alzheimer's disease: interactive influences on cognitive performance

Passamonti, L.; Tsvetanov, K.; Jones, P. S.; Bevan-Jones, W. R.; Arnold, R.; Borchert, R. J.; Mak, F. K.; Su, L.; O'Brien, J. T.; Rowe, J. B.

10.1101/532291 — neuroscience — Posted on 2019-01-28

520 Disease-associated scaffold protein CNK2 modulates PSD size and influences trafficking of new synaptic binding partner TNIK

Zieger, H.; Kunde, S.-A.; Rademacher, N.; Schmerl, B.; Shoichet, S.

10.1101/532374 — neuroscience — Posted on 2019-01-28

521 Investigating the role of exudates in recruiting Streptomyces bacteria to the Arabidopsis thaliana root microbiome

Worsley, S. F.; Macey, M. C.; Newitt, J. T.; Patrick, E.; Yu, D. W.; Wilkinson, B.; Murrell, C.; Hutchings, M. I.

10.1101/532309 — microbiology — Posted on 2019-01-28

522 Systems Analysis of Subjects Acutely Infected with Chikungunya Virus

Soares-Schanoski, A.; Baptista-Cruz, N.; Castro-Jorge, L. A.; Carvalho, R. V.; Santos, C. A.; Ros, N.; Oliveira, U.; Costa, D. D.; Santos, C. L.; Cunha, M. P.; Oliveira, M. L.; Alves, J. C.; Ocea, R. A.; Ribeiro, D. R.; Goncalves, A. N.; Gonzalez, P.; Suhrbier, A.; Zanotto, P. M.; Azevedo, I. J.; Zamboni, D. S.; Almeida, R. P.; Ho, P. L.; Kalil, J.; Nishiyama-Jr, M. Y.; Nakaya, H. I.

10.1101/531921 — immunology — Posted on 2019-01-28

523 3D super-resolution imaging using a generalized and scalable progressive refinement method on sparse recovery (PRIS)

Yi, X.; Piestun, R.; Weiss, S.

10.1101/532143 — bioinformatics — Posted on 2019-01-28

524 Enhancing experimental signals in single-cell RNA-sequencing data using graph signal processing

Burkhardt, D. B.; Stanley, J. S.; Perdigoto, A. L.; Gigante, S. A.; Herold, K. C.; Wolf, G.; Giraldez, A.; van Dijk, D.; Krishnaswamy, S.

10.1101/532846 — bioinformatics — Posted on 2019-01-28

525 Investigating metabolic interactions in a microbial co-culture through integrated modelling and experiments

Ravikrishnan, A.; Blank, L. M.; Srivastava, S.; Raman, K.

10.1101/532184 — systems biology — Posted on 2019-01-28

526 LSD impairs working memory, executive functions, and cognitive flexibility, but not risk-based decision making

Pokorny, T.; Duerler, P.; Seifritz, E.; Vollenweider, F. X.; Preller, K. H.

10.1101/532234 — pharmacology and toxicology — Posted on 2019-01-28

527 A Single-Molecule Long-Read Survey of Human Transcriptomes using LoopSeq Synthetic Long Read Sequencing

Wu, I.; Ben-Yehezkel, T.

10.1101/532135 — genomics — Posted on 2019-01-28

528 Inference and analysis of population-specific fine-scale recombination maps across 26 diverse human populations

Spence, J. P.; Song, Y. S.

10.1101/532168 — evolutionary biology — Posted on 2019-01-28

529 Overcoming ibrutinib resistance by targeting phosphatidylinositol-3-kinase signaling in diffuse large B-cell lymphoma

Jain, N.; Havranek, O.; Singh, R. K.; Khashab, T.; Shirazi, F.; Samaniego, F.; Sehgal, L.

10.1101/523761 — cancer biology — Posted on 2019-01-28

530 Evaluating potential drug targets through human loss-of-function genetic variation

10.1101/530881 — genomics — Posted on 2019-01-28

531 Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes

10.1101/531210 — genomics — Posted on 2019-01-28

532 Long-distance dispersal shaped the diversity of tribe Dorstenieae (Moraceae)

Zhang, Q.; Gardner, E.; Zerega, N.; Sauquet, H.

10.1101/531855 — evolutionary biology — Posted on 2019-01-28

533 PGCN: Disease gene prioritization by disease and gene embedding through graph convolutional neural networks

Li, Y.; Kuwahara, H.; Yang, P.; Song, L.; Gao, X.

10.1101/532226 — bioinformatics — Posted on 2019-01-28

534 Association between ApoE polymorphism and type 2 diabetes: A meta-analysis of 59 studies

Ren, S.; Chen, D.; Shi, J.; Li, Y.; Yang, Y.; Yang, H.

10.1101/530899 — genetics — Posted on 2019-01-28

535 Resting-state fMRI Signals of Intelligent People Wander in a Larger Space

Dizaji, A. S.; Khodaei, M.-R.; Soltanian-Zadeh, H.

10.1101/529362 — neuroscience — Posted on 2019-01-28

536 Redating of the To’aga site (Ofu Island, Manu'a) and a revised chronology for the Lapita to Polynesian Plainware transition in Tonga and Samoa

Petchey, F.; Kirch, P. V.

10.1101/532648 — biochemistry — Posted on 2019-01-28

537 Link clustering explains non-central essential genes in protein interaction networks

Kim, I.; Lee, H.; Han, S. K.; Lee, K.; Kim, S.

10.1101/532770 — systems biology — Posted on 2019-01-28

538 High prevalence of class 1 integrase and characterization of class 1 integron gene cassettes in multiresistant bacteria isolated from the gut microbiota of extended antibiotic treated Salmo salar fish farms

Vasquez Ponce, F.; Higuera Llanten, S.; Cortes Salinas, J.; Zimin Veselkoff, N.; Marshall Gonzalez, S. H.; Mardones, F. O.; Olivares-Pacheco, J.

10.1101/532663 — microbiology — Posted on 2019-01-28

539 How to fit in: The learning principles of cell differentiation

Brun-Usan, M.; Watson, R.

10.1101/532747 — evolutionary biology — Posted on 2019-01-28

540 Predicting kinase inhibitors using bioactivity matrix derived informer sets

Zhang, H.; Ericksen, S. S.; Lee, C.-p.; Ananiev, G. E.; Wlodarchak, N.; Mitchell, J. C.; Gitter, A.; Wright, S. J.; Hoffmann, F. M.; Wildman, S. A.; Newton, M. A.

10.1101/532762 — pharmacology and toxicology — Posted on 2019-01-28

541 Quality of Whole Genome Sequencing from Blood versus Saliva Derived DNA in Cardiac Patients

Yao, R.; Akinrinade, O.; Chaix, M.; Mital, S.

10.1101/532564 — genomics — Posted on 2019-01-28

542 Diagnosed and undiagnosed Diabetes mellitus among urban adults: a population based cross-sectional study

Ayele, B. H.; Shore, H.; Shunu, A.; Mengesha, M. M.

10.1101/532705 — epidemiology — Posted on 2019-01-28

543 Rosiglitazone in the thawing medium improves mitochondrial function in stallion spermatozoa through Akt phosphorylation and reduction of caspase 3

Ortiz Rodriguez, J. M.; BALAO DA SILVA, C.; MASOT, J.; REDONDO, E.; GAZQUEZ, A.; GIL, C.; ORTEGA, C.; Pena, F. J.

10.1101/532689 — cell biology — Posted on 2019-01-28

544 Accurate prediction of bacterial two-component signaling with a deep recurrent neural network ORAKLE

Balewski, J.; Hallberg, Z.

10.1101/532721 — bioinformatics — Posted on 2019-01-28

545 Epidemiology of Childhood Blindness: a Community based study in Bangladesh

Hussain, A. E.; Ferdoush, J.; Mashreky, S. R.; Rahman, A. F.; Ferdausi, N.; Dalal, K.

10.1101/532655 — epidemiology — Posted on 2019-01-28

546 Primary Studies on the Effect of Microbially Coalbed Methane Enhancement in Suit in the Qinshui Basin

Xiao, D.; Zhang, C.; Wang, E.; He, H.; Zhang, Y.; Wu, J.; Deng, L.; Wang, M.

10.1101/532671 — bioengineering — Posted on 2019-01-28

547 A rationally designed mimotope library for profiling of the human IgM repertoire

Pashov, A. D.; Shivarov, V.; Hadzhieva, M.; Kostov, V.; Ferdinandov, D.; Heinz, K.-M.; Pashova, S.; Todorova, M.; Vassilev, T. L.; Kieber-Emmons, T.; Meza-Zepeda, L. A.; Hovig, E.

10.1101/308973 — immunology — Posted on 2019-01-28

548 Cyclical environments drive variation in life history strategies: a general theory of cyclical phenology

Park, J. S.

10.1101/450387 — ecology — Posted on 2019-01-28

549 GUN1 regulates tetrapyrrole biosynthesis

Shimizu, T.; Mochizuki, N.; Nagatani, A.; Watanabe, S.; Shimada, T.; Tanaka, K.; Hayashi, Y.; Arai, M.; Kacprzak, S. M.; Leister, D.; Okamoto, H.; Terry, M.; Masuda, T.

10.1101/532036 — plant biology — Posted on 2019-01-28

550 Multivariate Pattern Classification of Primary Insomnia Using Three Types of Functional Connectivity Features

Dong, M.; Li, C.; Yin, Y.; Hua, K.; Fu, S.; Wu, Y.; Jiang, G.

10.1101/532127 — neuroscience — Posted on 2019-01-28

551 Open Community Challenge Reveals Molecular Network Modules with Key Roles in Diseases

Choobdar, S.; Ahsen, M. E.; Crawford, J.; Tomasoni, M.; Fang, T.; Lamparter, D.; Lin, J.; Hescott, B.; Hu, X.; Mercer, J.; Natoli, T.; Narayan, R.; The DREAM Module Identification Challenge Consortium, ; Subramanian, A.; Zhang, J. D.; Stolovitzky, G.; Kutalik, Z.; Lage, K.; Slonim, D. K.; Saez-Rodriguez, J.; Cowen, L. J.; Bergmann, S.; Marbach, D.

10.1101/265553 — bioinformatics — Posted on 2019-01-28

552 Draft genome sequence of the Solanum aethiopicum provides insights into disease resistance, drought tolerance and the evolution of the genome

Song, B.; Song, Y.; Fu, Y.; Kizito, E. B.; Kabod, P. N.; Liu, H.; Kamenya, S. N.; Muthemba, S.; Kariba, R.; Li, X.; Wang, S.; Cheng, S.; Muchugi, A.; Jamnadass, R.; Shapiro, H.-Y.; Deynze, A. V.; Yang, H.; Wang, J.; Xu, X.; Odeny, D. A.; Liu, X.

10.1101/532077 — genomics — Posted on 2019-01-28

553 Automated identification of Cell Types in Single Cell RNA Sequencing

Ma, F.; Pellegrini, M.

10.1101/532093 — bioinformatics — Posted on 2019-01-28

554 Searching for sympatric speciation in the genomic era

Richards, E.; Servedio, M.; Martin, C.

10.1101/367623 — evolutionary biology — Posted on 2019-01-28

555 Divergent mutational processes distinguish hypoxic and normoxic tumours

Bhandari, V.; Li, C. H.; Bristow, R. G.; Boutros, P. C.; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network,

10.1101/531996 — cancer biology — Posted on 2019-01-28

556 The fitness cost of a congenital heart defect shapes its genetic architecture

Akhirome, E. O.; Regmi, S. D.; Magnan, R.; Ugwu, N.; Qin, Y.; Schulkey, C. E.; Cheverud, J. M.; Jay, P. Y.

10.1101/531988 — genetics — Posted on 2019-01-27

557 Depletion of hemoglobin transcripts and long read sequencing improves the transcriptome annotation of the polar bear (Ursus maritimus)

Byrne, A.; Supple, M. A.; Volden, R.; Laidre, K. L.; Shapiro, B.; Vollmers, C.

10.1101/527978 — genomics — Posted on 2019-01-27

558 The Glossina Genome Cluster: Comparative Genomic Analysis of the Vectors of African Trypanosomes

Attardo, G. M.; Abd-Alla, A. M. M.; Acosta-Serrano, A.; Allen, J. E.; Bateta, R.; Benoit, J.; Bourtzis, K.; Caers, J.; Caljon, G.; Christensen, M. B.; Farrow, D. W.; Friedrich, M.; Hua-Van, A.; Jennings, E. C.; Larkin, D. M.; Lawson, D.; Lehane, M. J.; Lenis, V. P.; Lowy-Gallego, E.; Macharia, R. W.; Malacrida, A. R.; Marco, H. G.; Masiga, D.; Maslen, G. L.; Matetovici, I.; Meisel, R. P.; Meki, I.; Michalkova, V.; Miller, W. J.; Minx, P.; Mireji, P. O.; Ometto, L.; Parker, A. G.; Rio, R.; Rose, C.; Rosendale, A. J.; Rota Stabelli, O.; Savini, G.; Schoofs, L.; Scolari, F.; Swain, M. T.; Takac,

10.1101/531749 — genomics — Posted on 2019-01-27

559 Summary statistic analyses do not correct confounding bias

Holmes, J. B.; Speed, D.; Balding, D. J.

10.1101/532069 — genetics — Posted on 2019-01-27

560 Environmental selection and spatiotemporal structure of a major group of soil protists (Rhizaria: Cercozoa) in a temperate grassland

Fiore-Donno, A. M.; Richter-Heitmann, T.; Degrune, F.; Dumack, K.; Regan, K.; Mahran, S.; Boeddinghaus, R.; Rillig, M.; Friedrich, M. W.; Kandeler, E.; Bonkowski, M.

10.1101/531970 — ecology — Posted on 2019-01-27

561 Bone marrow stromal cells from a GDF5 origin produce zonal tendon-to-bone attachments following anterior cruciate ligament reconstruction

Hagiwara, Y.; Dyrna, F.; Kuntz, A. F.; Adams, D. J.; Dyment, N. A.

10.1101/532002 — bioengineering — Posted on 2019-01-27

562 Exosome labeling by lipophilic dye PKH26 results in significant increase in vesicle size

Dehghani, M.; Gulvin, S. M.; Flax, J.; Gaborski, T. R.

10.1101/532028 — biochemistry — Posted on 2019-01-27

563 Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

Edgar, R. J.; van Hensbergen, V. P.; Ruda, A.; Turner, A. G.; Deng, P.; Le Breton, Y.; El-Sayed, N. M.; Belew, A. T.; McIver, K. S.; McEwan, A. G.; Morris, A. J.; Lambeau, G.; Walker, M. J.; Rush, J. S.; Korotkov, K. V.; Widmalm, G.; van Sorge, N. M.; Korotkova, N.

10.1101/337519 — microbiology — Posted on 2019-01-27

564 A spike-timing-dependent plasticity rule for single, clustered and distributed dendritic spines

Tazerart, S.; Mitchell, D. E.; Miranda-Rottmann, S.; Araya, R.

10.1101/397323 — neuroscience — Posted on 2019-01-27

565 Centering based on active diffusion in mouse oocytes is non-specific

Verlhac, M.-H.; Colin, A.; Ratzin, N.; Almonacid, M.; Ahmed, W.; Betz, T.; Terret, M.-E.; Gov, N.; Voituriez, R.; Gueroui, Z.

10.1101/531657 — cell biology — Posted on 2019-01-27

566 Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma

Mondello, P.; Tadros, S.; Teater, M.; Fontan, L.; Chang, A.; Jain, N.; Singh, S.; Ma, M. C. J.; Yang, H.; Toska, E.; Alig, S.; Durant, M.; de Stanchina, E.; Mottok, A.; Nastoupil, L.; Neelapu, S.; Weigert, O.; Inghirami, G.; Baselga, J.; Dhogan, A.; Younes, A.; Yee, C.; Scheinberg, D.; Melnick, A.; Green, M.

10.1101/531954 — cancer biology — Posted on 2019-01-27

567 Applying CRISPR-based genetic screens to identify drivers of tumor-cell sensitivity towards NK-cell attack

Klein, K.; Wang, T.; Lander, E. S.; Altfeld, M.; Garcia-Beltran, W. F.

10.1101/531962 — immunology — Posted on 2019-01-27

568 Long-term synaptic plasticity in hippocampal neurogliaform interneurons

Mercier, M. S.; Magloire, V.; Cornford, J. H.; Kullmann, D. M.

10.1101/531822 — neuroscience — Posted on 2019-01-27

569 Early Life Adversity, but not suicide, is associated with less prefrontal cortex gray matter in adulthood

Underwood, M. D.; Bakalian, M.; Escobar, T.; Kassir, S.; Mann, J. J.; Arango, V.

10.1101/531871 — neuroscience — Posted on 2019-01-27

570 MOU-EC: model-based whole-brain effective connectivity to extract biomarkers for brain dynamics from fMRI data and study distributed cognition

Gilson, M.; Zamora-Lopez, G.; Pallares, V.; Adhikari, M. H.; Senden, M.; Tauste Campo, A.; Mantini, D.; Corbetta, M.; Deco, G.; Insabato, A.

10.1101/531830 — neuroscience — Posted on 2019-01-27

571 Testing for batch effect through age predictors

Mamoshina, P.; Kochetov, K.; Putin, E.; Aliper, A.; Zhavoronkov, A.

10.1101/531863 — bioinformatics — Posted on 2019-01-27

572 Applications of Machine Learning in Decision Analysis for Dose Management for Dofetilide

Levy, A. E.; Biswas, M.; Weber, R.; Tarakji, K.; Chung, M.; Noseworthy, P. A.; Newton-Cheh, C.; Rosenberg, M. A.

10.1101/531285 — pharmacology and toxicology — Posted on 2019-01-27

573 The Impact of Uremia and Intestinal Dysbiosis on Hepatic Drug Metabolism in a Rat Model of Progressive Chronic Kidney Disease

Hartjes, E. D.; Lim, Y. J.; Velenosi, T. J.; Al, K. F.; Macklaim, J. M.; Kucey, A. S.; Reid, G.; Burton, J. P.; Gloor, G. B.; Urquhart, B. L.

10.1101/531939 — pharmacology and toxicology — Posted on 2019-01-27

574 Developmental Changes in Movement Related Brain Activity in Early Childhood

Johnson, B.; Jobst, C.; Al-Loos, R.; He, W.; Cheyne, D.

10.1101/531905 — neuroscience — Posted on 2019-01-27

575 Positive effects of low LDL-C and statins on bone mineral density: an integrated epidemiological observation analysis and Mendelian Randomization study

Li, G. H.-Y.; Cheung, C.-L.; Au, P. C.-M.; Tan, K. C.-B.; Wong, I. C.-K.; Sham, P.-C.

10.1101/531137 — epidemiology — Posted on 2019-01-27

576 Effects of variations in adaptation potential on invasion speeds and species ranges

Mendez-Vera, J.; Raoul, G.; Massol, F.; Loeuille, N.

10.1101/529735 — ecology — Posted on 2019-01-27

577 Extinctions in marine plankton preceded by stabilizing selection

Weinkauf, M. F. G.; Bonitz, F. G. W.; Martini, R.; Kucera, M.

10.1101/531947 — ecology — Posted on 2019-01-27

578 Force-profile analysis of the cotranslational folding of HemK and filamin domains: Comparison of biochemical and biophysical folding assays

Kemp, G.; Kudva, R.; de la Rosa, A.; von Heijne, G.

10.1101/470831 — molecular biology — Posted on 2019-01-27

579 Geochemical and metagenomic characterization of Jinata Onsen, a Proterozoic-analog hot spring, reveals novel microbial diversity including iron-tolerant phototrophs and thermophilic lithotrophs

Ward, L. M.; Idei, A.; Nakagawa, M.; Ueno, Y.; Fischer, W. W.; McGlynn, S. E.

10.1101/428698 — microbiology — Posted on 2019-01-27

580 Erroneous inference based on a lack of preference within one group: autism, mice, and the Social Approach Task.

Nygaard, K. R.; Maloney, S. E.; Dougherty, J. D.

10.1101/530279 — animal behavior and cognition — Posted on 2019-01-27

581 To integrate or not to integrate: Temporal dynamics of hierarchical Bayesian Causal Inference

Aller, M.; Noppeney, U.

10.1101/504118 — neuroscience — Posted on 2019-01-27

582 Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer disease: meta-analysis of 11 cohort studies

Creese, B.; Vassos, E.; Bergh, S.; Athanasiu, L.; Johar, I.; Rongve, A.; Tondel Medboen, I.; Vasconcelos Da Silva, M.; Aakhus, E.; Andersen, F.; Battella, F.; Braekhus, A.; Djurovic, S.; Paroni, G.; Proitsi, P.; Saltvedt, I.; Seripa, D.; Stordal, E.; Fladby, T.; Aarsland, D.; Andreassen, O. A.; Ballard, C.; Selbaek, G.

10.1101/528802 — genomics — Posted on 2019-01-27

583 Prion-like spreading of Alzheimer's disease within the brain's connectome

Fornari, S.; Schafer, A.; Jucker, M.; Goriely, A.; Kuhl, E.

10.1101/529438 — neuroscience — Posted on 2019-01-27

584 Modelling conduction delays in the corpus callosum using MRI-measured g-ratio

Berman, S.; Filo, S.; Mezer, A. A.

10.1101/479881 — neuroscience — Posted on 2019-01-27

585 The proteome of Tetrasphaera elongata is adapted to changing conditions in wastewater treatment plants

Herbst, F.-A.; Dueholm, M. S.; Wimmer, R.; Nielsen, P. H.

10.1101/513143 — microbiology — Posted on 2019-01-27

586 Mangrove leaf and root traits and their relation to urbanization

Branoff, B.

10.1101/506196 — ecology — Posted on 2019-01-27

587 Comprehensive evaluation of computational cell-type quantification methods for immuno-oncology

Sturm, G.; Finotello, F.; Petitprez, F.; Zhang, J. D.; Baumbach, J.; Fridman, W. H.; List, M.; Aneichyk, T.

10.1101/463828 — bioinformatics — Posted on 2019-01-27

588 Is the LAN effect in morphosyntactic processing an ERP artifact?

Caffarra, S.; Mendoza, M.; Davidson, D.

10.1101/218594 — neuroscience — Posted on 2019-01-27

589 Network analysis of whole-brain fMRI dynamics: A newframework based on dynamic communicability

Gilson, M.; Kouvaris, N. E.; Deco, G.; Mangin, J.-F.; Poupon, C.; Lefranc, S.; Riviere, D.; Zamora-Lopez, G.

10.1101/421883 — neuroscience — Posted on 2019-01-27

590 Cell-projection pumping: A hydrodynamic cell-stiffness dependent mechanism for cytoplasmic transfer between mammalian cells

Zoellner, H.; Paknejad, N.; Cornwell, J.; Chami, B.; Romin, Y.; Boykov, V.; Fujisawa, S.; Kelly, E.; Lynch, G. W.; Rogers, G.; Manova, K.; Moore, M. A.

10.1101/531798 — cell biology — Posted on 2019-01-27

591 DNA methylation and histone H1 cooperatively repress transposable elements and aberrant intragenic transcripts

Choi, J.; Lyons, D. B.; Kim, Y.; Moore, J. D.; Zilberman, D.

10.1101/527523 — genetics — Posted on 2019-01-27

592 Dual airway and alveolar contributions to adult lung homeostasis and carcinogenesis

Spella, M.; Lilis, I.; Pepe, M. A.; Chen, Y.; Armaka, M.; Lamort, A.-S.; Zazara, D. E.; Roumelioti, F.; Vreka, M.; Kanellakis, N. I.; Wagner, D. E.; Giannou, A. D.; Armenis, V.; Arendt, K. A. M.; Klotz, L. V.; Toumpanakis, D.; Karavana, V.; Zakynthinos, S. G.; Giopanou, I.; Marazioti, A.; Aidinis, V.; Sotillo, R.; Stathopoulos, G. T.

10.1101/531780 — cancer biology — Posted on 2019-01-27

593 Flexible pivoting of the pleckstrin domain domain in dynamin catalyzes fission by affecting membrane properties: Insights into the molecular degrees of freedom

Jha, K.; Baratam, K.; Dubey, V.; Pucadyil, T.; Srivastava, A.

10.1101/531814 — biophysics — Posted on 2019-01-27

594 Discovery of biased orientation of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2019-01-27

595 MISSED OPPORTUNITIES OF CHLAMYDIA AND GONORRHEA DETECTION WHEN NOT USING EXTRA GENITAL SCREENING AMONG MALES

Schafer, C. A.; Prado, B.; Barin, N.; Gama, L.

10.1101/428706 — epidemiology — Posted on 2019-01-27

596 A computational pipeline to determine lobular electric field distribution during cerebellar transcranial direct current stimulation

Rezaee, Z.; Dutta, A.

10.1101/531699 — neuroscience — Posted on 2019-01-27

597 Phylogenetic systematics and evolution of the spider infraorder Mygalomorphae using genomic scale data

Opatova, V.; Hamilton, C. A.; Hedin, M.; Montes de Oca, L.; Kral, J.; Bond, J. E.

10.1101/531756 — evolutionary biology — Posted on 2019-01-27

598 The Minimum Environmental Perturbation Principle: A New Perspective on Niche Theory

Marsland, R.; Cui, W.; Mehta, P.

10.1101/531640 — ecology — Posted on 2019-01-27

599 Regulation and dynamics of force transmission at individual cell-matrix adhesion bonds

Tan, S. J.; Chang, A. C.; Miller, C. M.; Anderson, S. M.; Prahl, L. S.; Odde, D. J.; Dunn, A. R.

10.1101/530469 — cell biology — Posted on 2019-01-27

600 Tumor-Intrinsic Response to IFNgamma Shapes the Tumor Microenvironment and Anti-PD-1 Response in NSCLC

Bullock, B. L.; Kimball, A. K.; Poczobutt, J. M.; Li, H. Y.; Kwak, J. W.; Neuwelt, A. J.; Johnson, A. M.; Kleczko, E.; Kaspar, R.; Hopp, K.; Schenk, E.; Weiser-Evans, M. C.; Clambey, E. T.; Nemenoff, R. A.

10.1101/531236 — cancer biology — Posted on 2019-01-27

601 SLM-Transform: A Method for Memory-Efficient Indexing of Spectra for Database Search in LC-MS/MS Proteomics

Haseeb, M.; Awan, M. G.; Cadigan, A.; Saeed, F.

10.1101/531681 — bioinformatics — Posted on 2019-01-27

602 Assessing metadata and curation quality: a case study from the development of a third-party curation service at Springer Nature

Grant, R.; Smith, G.; Hrynaszkiewicz, I.

10.1101/530691 — scientific communication and education — Posted on 2019-01-27

603 Computational geometric tools for modeling inherent variability in animal behavior

Stamps, M. T.; Go, S. H.; Mathuru, A. S.

10.1101/531392 — neuroscience — Posted on 2019-01-26

604 Prefrontal oscillations modulate the propagation of neuronal activity required for working memory

Sherfey, J. S.; Ardid, S.; Miller, E. K.; Hasselmo, M. E.; Kopell, N. J.

10.1101/531574 — neuroscience — Posted on 2019-01-26

605 Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

Edwards, R.; Vega, A.; Norman, H.; Ohaeri, M. C.; Levi, K.; Dinsdale, E.; Cinek, O.; Aziz, R.; McNair, K.; Barr, J.; Bibby, K.; Brouns, S.; Cazares, A.; de Jonge, P. A.; Desnues, C.; Diaz-Munoz, S.; Fineran, P.; Kurilshikov, A.; Lavigne, R.; Mazankova, K.; McCarthy, D.; Nobrega, F.; Reyes, A.; Tapia, G.; Trefault, N.; Tyakht, A.; Vinuesa, P.; Wagemans, J.; Zhernakova, A.; Aarestrup, F.; Ahmadov, G.; Alassaf, A.; Anton, J.; Asangba, A.; Billings, E.; Cantu, A.; Carlton, J.; Cazares Lopez, D.; Cho, G.-S.; Condeff, T.; Cortes, P.; Cranfield, M.; Cuevas, D.; De la Iglesia, R.; Decewicz, P.; Doane,

10.1101/527796 — microbiology — Posted on 2019-01-26

606 De novo assembly, delivery and expression of a 101 kb human gene in mouse cells

Mitchell, L. A.; McCulloch, L. H.; Pinglay, S.; Berger, H.; Bosco, N.; Brosh, R.; Bulajic, M.; Huang, E.; Martin, J. A.; Hogan, M. S.; Mazzoni, E.; Davoli, T.; Maurano, M. T.; Boeke, J. D.

10.1101/423426 — genetics — Posted on 2019-01-26

607 Relation between prescribing of different antibiotics and rates of bacteremia/septicemia and associated mortality in the US and England

Goldstein, E.

10.1101/527101 — epidemiology — Posted on 2019-01-26

608 Phase-amplitude coupling of neural oscillations can be effectively probed with concurrent TMS-EEG

Glim, S.; Okazaki, Y. O.; Nakagawa, Y.; Mizuno, Y.; Hanakawa, T.; Kitajo, K.

10.1101/273482 — neuroscience — Posted on 2019-01-26

609 A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

Gittens, W.; Johnson, D. J.; Allison, R. M.; Cooper, T. J.; Thomas, H.; Neale, M. J.

10.1101/530667 — molecular biology — Posted on 2019-01-26

610 Antitumor effects of Tv1 venom peptide in liver cancer

Anand, P.; Filipenko, P.; Huaman, J.; Lyudmer, M.; Hossain, M.; Santamaria, C.; Huang, K.; Ogunwobi, O.; Holford, M.

10.1101/518340 — cancer biology — Posted on 2019-01-26

611 Available energy fluxes drive a transition in the diversity, stability, and functional structure of microbial communities

Marsland, R.; Cui, W.; Goldford, J. E.; Sanchez, A.; Korolev, K.; Mehta, P.

10.1101/335893 — biophysics — Posted on 2019-01-26

612 Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococci

Chatterjee, A.; Johnson, C. N.; Luong, P.; Hullahalli, K.; McBride, S. W.; Schubert, A. M.; Palmer, K. L.; Carlson, P. E.; Duerkop, B. A.

10.1101/531442 — microbiology — Posted on 2019-01-26

613 PolyCRACKER, a robust method for the unsupervised partitioning of polyploid subgenomes by signatures of repetitive DNA evolution

Gordon, S. P.; Levy, J. J.; Vogel, J. P.

10.1101/484832 — genomics — Posted on 2019-01-26

614 Minimal effects of spargel (PGC-1α) overexpression in a Drosophila mitochondrial disease model

George, J.; Jacobs, H. T.

10.1101/529545 — molecular biology — Posted on 2019-01-26

615 Analysis of Brevundimonas subvibrioides developmental signaling systems reveals unexpected differences between phenotypes and c-di-GMP levels

Sperling, L.; Kaever, V.; Curtis, P. D.

10.1101/531418 — microbiology — Posted on 2019-01-26

616 ATAC-seq signal processing and recurrent neural networks can identify RNA polymerase activity

Tripodi, I. J.; Chowdhury, M.; Dowell, R. D.

10.1101/531517 — bioinformatics — Posted on 2019-01-26

617 Targeted Cleavage and Polyadenylation of RNA by CRISPR-Cas13

Anderson, K. M.; Poosala, P.; Lindley, S. R.; Anderson, D. M.

10.1101/531111 — molecular biology — Posted on 2019-01-26

618 Graphene oxide affects soil bacterial and fungal diversity even at parts-per-trillion concentrations

Forstner, C.; Orton, T. G.; Skarshewski, A.; Wang, P.; Kopittke, P. M.; Dennis, P. G.

10.1101/530485 — microbiology — Posted on 2019-01-26

619 Distribution Pattern and Diversity Maintenance Mechanism of the Denitrifier Community in Alkaline Copper Mine Drainage

Liu, J.; Li, C.; Luo, Z.; Wang, X.; Bao, J.; Chai, B.

10.1101/531434 — microbiology — Posted on 2019-01-26

620 IFN-alpha and 5-Aza-2-deoxycytidine enhance the anti-tumor efficacy of a dendritic-cell targeting MIP3alpha-Gp100-Trp2 DNA vaccine by affecting T-cell recruitment and tumor microenvironment gene expression

Gordy, J.; Luo, K.; Markham, R.

10.1101/531616 — immunology — Posted on 2019-01-26

621 Mucoromycotina fine root endophyte fungi form nutritional mutualisms with vascular plants.

Hoysted, G. A.; Jacob, A. S.; Kowal, J.; Gieseman, P.; Bidartondo, M. I.; Duckett, J. G.; Gebauer, G.; Rimington, W. R.; Schornack, S.; Pressel, S.; Field, K. J.

10.1101/531103 — plant biology — Posted on 2019-01-26

622 Analysis of Vibrio cholerae genomes using a novel bioinformatic tool identifies new, active Type VI Secretion System gene clusters

Crisan, C. V.; Chande, A. T.; Williams, K.; Raghuram, V.; Rishishwar, L.; Steinbach, G.; Yunker, P.; Jordan, K. I.; Hammer, B. K.

10.1101/526723 — microbiology — Posted on 2019-01-26

623 Werner syndrome helicase is a selective vulnerability of microsatellite instability high tumor cells

Lieb, S.; Blaha-Ostermann, S.; Kamper, E.; Ehrenhoefer-Woelfer, K.; Schlattl, A.; Wernitznig, A.; Lipp, J. J.; Nagasaka, K.; Bader, G.; Neumueller, R. A.; Kraut, N.; Pearson, M. A.; Petronczki, M.; Woehrle, S.

10.1101/530659 — cancer biology — Posted on 2019-01-26

624 Active information sampling varies across the cardiac cycle

Kunzendorf, S.; Klotzsche, F.; Akbal, M.; Villringer, A.; Ohl, S.; Gaebler, M.

10.1101/283838 — neuroscience — Posted on 2019-01-26

625 Optimal sparse olfactory representations persist in a plastic network

Assisi, C.; Stopfer, M.; Bazhenov, M.

10.1101/528125 — neuroscience — Posted on 2019-01-26

626 Evolution of life cycles and reproductive traits: insights from 1 the brown algae

Heesch, S.; Serrano-Serrano, M.; Luthringer, R.; Peters, A. F.; Destombe, C.; Cock, J. M.; Valero, M.; Roze, D.; Salamin, N.; coelho, s. m.

10.1101/530477 — evolutionary biology — Posted on 2019-01-26

627 ADAMDEC1 maintains a novel growth factor signaling loop in cancer stem cells

Hale, J. S.; Jimenez-Pascual, A.; Kordowski, A.; Pugh, J.; Rao, S.; Silver, D. J.; Alban, T.; Watson, D. B.; Chen, R.; McIntyre, T. M.; Colombo, G.; Taraboletti, G.; Holmberg, K. O.; Forsberg-Nilsson, K.; Lathia, J. D.; Siebzehnrubl, F.

10.1101/531509 — cancer biology — Posted on 2019-01-26

628 Ncl1 mediated metabolic rewiring is critical during metabolic stress

Bhat, A.; Chakraborty, R.; Adlakha, K.; Agam, G.; Chakraborty, K.; Sengupta, S.

10.1101/529578 — biochemistry — Posted on 2019-01-26

629 Tempo of gene regulation in wild and cultivated Vitis species shows coordination between cold deacclimation and budbreak

Pacheco Kovaleski, A.; Londo, J. P.

10.1101/528828 — plant biology — Posted on 2019-01-26

630 Corrective muscle activity reveals subject-specific sensorimotor recalibration.

Iturralde, P. A.; Torres-Oviedo, G.

10.1101/372359 — neuroscience — Posted on 2019-01-26

631 Using environmental DNA for the detection of Schistosoma mansoni: toward improved environmental surveillance of schistosomiasis

Sengupta, M. E.; Hellstrom, M.; Kariuki, H. C.; Olsen, A.; Thomsen, P. F.; Mejer, H.; Willerslev, E.; Mwanje, M.; Madsen, H.; Kristensen, T. K.; Stensgaard, A.-S.; Vennervald, B. J.

10.1101/530592 — microbiology — Posted on 2019-01-26

632 Pacific geoduck (Panopea generosa) resilience to natural pH variation

Spencer, L. H.; Horwith, M.; Lowe, A. T.; Venkataraman, Y. R.; Timmins-Schiffman, E.; Nunn, B. L.; Roberts, S. B.

10.1101/432542 — physiology — Posted on 2019-01-26

633 E-cadherin endocytosis is modulated by p120-catenin through the opposing actions of RhoA and Arf1

Greig, J.; Bulgakova, N. A.

10.1101/477760 — cell biology — Posted on 2019-01-26

634 Collective excitations in alpha-helical protein structures interacting with environment

Kadantsev, V. N.; Goltsov, A.

10.1101/457580 — biophysics — Posted on 2019-01-26

635 Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes

10.1101/530824 — bioinformatics — Posted on 2019-01-26

636 Same-Species Contamination Detection with Variant Calling Information from Next Generation Sequencing

Jiang, T.; Buchkovich, M.; Motsinger-Reif, A.

10.1101/531558 — bioinformatics — Posted on 2019-01-26

637 Prefrontal oscillations modulate the propagation of neuronal activity required for working memory

Sherfey, J. S.; Ardid, S.; Miller, E. K.; Hasselmo, M. E.; Kopell, N. J.

10.1101/531574 — neuroscience — Posted on 2019-01-26

638 Optimisation and validation of hydrogel-based brain tissue clearing shows uniform expansion across anatomical regions and spatial scales

Tyson, A. L.; Akhtar, A.; Andreae, L. C.

10.1101/423848 — neuroscience — Posted on 2019-01-26

639 The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membrane-less granular phase-separation

10.1101/528638 — molecular biology — Posted on 2019-01-26

640 Diversity matters: Deep-sea mussels harbor multiple symbiont strains

Ansorge, R.; Romano, S.; Sayavedra, L.; Kupczok, A.; Tegetmeyer, H. E.; Dubilier, N.; Petersen, J.

10.1101/531459 — microbiology — Posted on 2019-01-26

641 Multi-CD: Multi-scale discovery of Chromatin Domains

Kim, M. H.; Bak, J. H.; Liu, L.; Hyeon, C.

10.1101/530519 — biophysics — Posted on 2019-01-26

642 MOLI: Multi-Omics Late Integration with deep neural networks for drug response prediction

Sharifi-Noghabi, H.; Zolotareva, O.; Collins, C. C.; Ester, M.

10.1101/531327 — bioinformatics — Posted on 2019-01-26

643 MagC, magnetic collection of ultrathin sections for volumetric correlative light and electron microscopy

Templier, T.

10.1101/526137 — neuroscience — Posted on 2019-01-26

644 Planning Face, Hand, and Leg Movements: Anatomical Constraints on Preparatory Inhibition.

Labruna, L.; Tischler, C.; Cazares, C.; Greenhouse, I.; Duque, J.; Lebon, F.; Ivry, R. B.

10.1101/529107 — neuroscience — Posted on 2019-01-26

645 Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

Cross-Disorder Group of the Psychiatric Genomics Consortium, ; Lee, P. H.; Anttila, V.; Won, H.; Feng, Y.-C. A.; Rosenthal, J.; Zhu, Z.; Tucker-Drob, E. M.; Nivard, M. G.; Grotzinger, A. D.; Posthuma, D.; Wang, M. M.- J.; Yu, D.; Stahl, E.; Walters, R. K.; Anney, R. J. L.; Duncan, L. E.; Belangero, S.; Luykx, J.; Kranzler, H.; Keski-Rahkonen, A.; Cook, E. H.; Kirov, G.; Coppola, G.; Kaprio, J.; Zai, C. C.; Hoekstra, P. J.; Banaschewski, T.; Rohde, L. A.; PGC Attention Deficit Hyperactivity Disorder Group, ; PGC Autism Spectrum Disorder Group, ; PGC Bipolar Disorder Group, ; PGC Eating Diso

10.1101/528117 — genomics — Posted on 2019-01-26

646 Requirement for TRanslocon-Associated Protein (TRAP) α in insulin biogenesis

Li, X.; Itani, O. A.; Haataja, L.; Dumas, K. J.; Yang, J.; Cha, J.; Flibotte, S.; Shih, H.-J.; Xu, J.; Qi, L.; Arvan, P.; Liu, M.; Hu, P. J.

10.1101/531491 — genetics — Posted on 2019-01-26

647 Activity-by-Contact model of enhancer specificity from thousands of CRISPR perturbations

Fulco, C. P.; Nasser, J.; Jones, T. R.; Munson, G.; Bergman, D. T.; Subramanian, V.; Grossman, S. R.; Anyoha, R.; Patwardhan, T. A.; Nguyen, T. H.; Kane, M.; Doughty, B.; Perez, E. M.; Durand, N. C.; Stamenova, E. K.; Lieberman Aiden, E.; Lander, E. S.; Engreitz, J. M.

10.1101/529990 — genetics — Posted on 2019-01-26

648 Ecological niche differentiation in soil cyanobacterial communities across the globe

Cano-Diaz, C.; Maestre, F. T.; Eldridge, D. J.; Singh, B. K.; Bardgett, R. D.; Fierer, N.; Delgado-Baquerizo, M.

10.1101/531145 — ecology — Posted on 2019-01-26

649 Lineage tracing analysis of cone photoreceptor-associated cis-regulatory elements in the developing chicken retina.

Schick, E.; McCaffery, S.; Keblish, E.; Thakurdin, C.; Emerson, M.

10.1101/531475 — developmental biology — Posted on 2019-01-26

650 Short-range interactions govern cellular dynamics in microbial multi-genotype systems

Dal Co, A.; van Vliet, S.; Kiviet, D. J.; Schlegel, S.; Ackermann, M.

10.1101/530584 — systems biology — Posted on 2019-01-26

651 Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice

Mukai, J.; Cannavo, E.; Sun, Z.; Crabtree, G.; Diamantopoulou, A.; Thakur, P.; Chang, C.-Y.; Cai, Y.; Lomvardas, S.; Takata, A.; Xu, B.; Gogos, J.

10.1101/529701 — neuroscience — Posted on 2019-01-26

652 CO2 conversion to methane and biomass in obligate methylotrophic methanogens in marine sediments

Yin, X.; Wu, W.; Maeke, M.; Richter-Heitmann, T.; Kulkarni, A.; Oni, O. E.; Wendt, J.; Elvert, M.; Friedrich, M. W.

10.1101/528562 — microbiology — Posted on 2019-01-26

653 Crosslinking Proteomics Indicates Effects of Simvastatin on the TLR2 interactome and Reveals ACTR1A as a Novel Regulator of the TLR2 Signal Cascade

Kamal, A. H. M.; Aloor, J. J.; Fessler, M. B.; Chowdhury, S.

10.1101/530402 — immunology — Posted on 2019-01-26

654 DPAC: a tool for Differential Poly(A) Site usage from poly(A) targeted RNAseq data

Routh, A. L.

10.1101/531590 — bioinformatics — Posted on 2019-01-26

655 Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole

Yesbolatova, A.; Natsume, T.; Hayashi, K.-i.; Kanemaki, M. T.

10.1101/530410 — bioengineering — Posted on 2019-01-26

656 Spatial sorting enables comprehensive characterization of liver zonation

Ben-Moshe, S.; Shapira, Y.; Moor, A. E.; Bahar Halpern, K.; Itzkovitz, S.

10.1101/529784 — systems biology — Posted on 2019-01-26

657 Loss of one Engrailed1 allele enhances induced α-synucleinopathy

Chatterjee, D.; Saiz Sanchez, D.; Quansah, E.; Rey, N. L.; George, S.; Becker, K.; Madaj, Z.; Steiner, J. A.; Ma, J.; Escobar Galvis, M. L.; Kordower, J. H.; Brundin, P.

10.1101/530915 — neuroscience — Posted on 2019-01-26

658 A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

Gittens, W.; Johnson, D. J.; Allison, R. M.; Cooper, T. J.; Thomas, H.; Neale, M. J.

10.1101/530667 — molecular biology — Posted on 2019-01-26

659 Benzoate-Tolerant Escherichia coli Strains from Experimental Evolution Lose the Gad Regulon, Multi-Drug Efflux Pumps, and Hydrogenases

Moore, J. P.; Li, H.; Engmann, M. L.; Bischof, K. M.; Kunka, K. S.; Harris, M. E.; Tancredi, A. C.; Ditmars, F. S.; Basting, P. J.; George, N. S.; Bhagwat, A. A.; Slonczewski, J. L.

10.1101/531178 — microbiology — Posted on 2019-01-26

660 Phototrophic Methane Oxidation in a Member of the Chloroflexi Phylum

Ward, L.; Shih, P. M.; Hemp, J.; Kakegawa, T.; Fischer, W. W.; McGlynn, S. E.

10.1101/531582 — microbiology — Posted on 2019-01-26

661 A Vaccine Composed of Antigen Fused to a Ligand for a Receptor on Immature Dendritic Cells Elicits Protective Antibody Responses to Malaria Sporozoites in Infant Macaques

Markham, R. B.; Luo, K.; Gordy, J.; Zavala, F.

10.1101/530840 — immunology — Posted on 2019-01-26

662 Identification of anonymous DNA using genealogical triangulation

Ellenbogen, P. M.; Narayanan, A.

10.1101/531269 — genomics — Posted on 2019-01-26

663 Genomic analysis of the four ecologically distinct cactus host populations of Drosophila mojavensis

Allan, C. W.; Matzkin, L. M.

10.1101/530154 — genomics — Posted on 2019-01-26

664 Coupling adaptive molecular evolution to phylodynamics using fitness-dependent birth-death models

Rasmussen, D. A.; Stadler, T.

10.1101/531525 — evolutionary biology — Posted on 2019-01-26

665 Phylogeny of Holarctic gall wasps of the genera Diplolepis and Periclistus (Hymenoptera: Cynipidae) based on DNA barcodes

Zhang, Y. M.; Laszlo, Z.; Looney, C.; Denes, A.-L.; Hanner, R. H.; Shorthouse, J. D.

10.1101/530949 — zoology — Posted on 2019-01-26

666 Towards an ″assayome″ for binary interactome mapping

Choi, S. G.; Olivet, J.; Cassonnet, P.; Vidalain, P.-O.; Luck, K.; Lambourne, L.; Spirohn, K.; Lemmens, I.; Dos Santos, M.; Demeret, C.; Jones, L.; Rangarajan, S.; Bian, W.; Coutant, E. P.; Janin, Y. L.; van der Werf, S.; De Las Rivas, J.; Tavernier, J.; Twizere, J.-C.; Hao, T.; Hill, D. E.; Vidal, M.; Calderwood, M. A.; Jacob, Y.

10.1101/530790 — systems biology — Posted on 2019-01-26

667 Is removal of weak connections necessary for graph-theoretical analysis of dense weighted structural connectomes?

Civier, O.; Smith, R. E.; Yeh, C.-H.; Connelly, A.; Calamante, F.

10.1101/531350 — neuroscience — Posted on 2019-01-26

668 Antero-posterior versus lateral vestibular input processing in human visual cortex

Aedo-Jury, F.; Cottereau, B. R.; Celebrini, S.; Severac Cauquil, A.

10.1101/530808 — neuroscience — Posted on 2019-01-26

669 Computational geometric tools for modeling inherent variability in animal behavior

Stamps, M. T.; Go, S. H.; Mathuru, A. S. S.

10.1101/531392 — neuroscience — Posted on 2019-01-26

670 BOLD signatures of sleep

Song, C.; Boly, M.; Tagliazucchi, E.; Laufs, H.; Tononi, G.

10.1101/531186 — neuroscience — Posted on 2019-01-26

671 Quantifying the Confidence in fMRI-based Language Lateralisation through Laterality Index Deconstruction

Wegrzyn, M.; Mertens, M.; Bien, C. G.; Woermann, F. G.; Labudda, K.

10.1101/530626 — neuroscience — Posted on 2019-01-26

672 Tracing the evolution of the plastome and mitogenome in the Chloropicophyceae uncovered convergent tRNA gene losses and a variant plastid genetic code

Turmel, M.; Lopes dos Santos, A.; Otis, C.; Sergerie, R.; Lemieux, C.

10.1101/530998 — genomics — Posted on 2019-01-26

673 Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer disease: meta-analysis of 10 cohort studies

10.1101/528802 — genomics — Posted on 2019-01-26

674 Asthma and affective traits in adults: a genetically informative study

Lehto, K.; Pedersen, N. L.; Almqvist, C.; Lu, Y.; Brew, B. K.

10.1101/530865 — genetics — Posted on 2019-01-26

675 Estimating virulence from relative survival

Agnew, P.

10.1101/530709 — evolutionary biology — Posted on 2019-01-26

676 Hera-T: an efficient and accurate approach for quantifying gene abundances from 10X-Chromium data with high rates of non-exonic reads.

Tran, T.; Truong, T.; Vuong, H.; Pham, S.

10.1101/530501 — bioinformatics — Posted on 2019-01-26

677 Engineered reversal of function in glycolytic yeast promoters

Rajkumar, A. S.; Oezdemir, E.; Lis, A. V.; Schneider, K.; Jensen, M. K. K.; Keasling, J. D.

10.1101/530717 — bioengineering — Posted on 2019-01-26

678 Lupin (Lupinus sp.) seeds exert anthelmintic activity associated with their alkaloid content

Dubois, O.; Allanic, C.; Charvet, C. L.; Guegnard, F.; Fevrier, H.; Thery-Kone, I.; Cortet, J.; Koch, C.; Bouvier, F.; Fassier, T.; Marcon, D.; Magnin-Robert, J.-B.; Peineau, N.; Courtot, E.; Huau, C.; Meynadier, A.; Enguehard-Gueiffier, C.; Neveu, C.; Boudesocque-Delaye, L.; Salle, G.

10.1101/530956 — pharmacology and toxicology — Posted on 2019-01-26

679 Proteolytic program-dependent functions are impaired in INF2-mediated focal segmental glomerulosclerosis.

Subramanian, B. K.; Chun, J.; Perez, C.; Yan, P.; Stillman, I.; Higgs, H.; Alper, S.; Schlondorff, J.; Pollak, M.

10.1101/530642 — pathology — Posted on 2019-01-26

680 Earliest-known intentionally deformed human cranial fossil from Asia and the initiation of hereditary hierarchy in the early Holocene

Ni, X.; Li, Q.; Stidham, T. A.; Yang, Y.; Ji, Q.; Jin, C.; Samiullah, K.

10.1101/530907 — paleontology — Posted on 2019-01-26

681 Large scale analysis of the diversity and complexity of the adult spinal cord neurotransmitter typology

Pedroni, A.; Ampatzis, K.

10.1101/518845 — neuroscience — Posted on 2019-01-26

682 High-pass filtering artifacts in multivariate classification of neural time series data

van Driel, J.; Olivers, C. N. L.; Fahrenfort, J. J.

10.1101/530220 — neuroscience — Posted on 2019-01-26

683 Comparative Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans

Celen, I.; Jayasinghe, A.; Doh, J.; Sabanayagam, C. R.

10.1101/531335 — genomics — Posted on 2019-01-26

684 Modelling structural constraints on protein evolution via side-chain conformational states

Perron, U.; Kozlov, A. M.; Stamatakis, A.; Goldman, N.; Moal, I.

10.1101/530634 — evolutionary biology — Posted on 2019-01-26

685 Seascape genetics at its finest: dispersal patchiness within a well-connected population

Schunter, C.; Pascual, M.; Raventos, N.; Garriga, J.; Garza, J. C.; Bartumeus, F.; Macpherson, E.

10.1101/530451 — ecology — Posted on 2019-01-26

686 A Short Bout of High-intensity Exercise Alters Ipsilesional Motor Cortical Excitability Post-stroke

Li, X.; Charalambous, C.; Reisman, D.; Morton, S.

10.1101/530857 — physiology — Posted on 2019-01-26

687 Antigen-specific humoral immune responses by CRISPR/Cas9-edited B cells

Hartweger, H.; McGuire, A. T.; Horning, M.; Taylor, J. J.; Dosenovic, P.; Yost, D.; Gazumyan, A.; Seaman, M. S.; Stamatatos, L.; Jankovic, M.; Nussenzweig, M. C.

10.1101/530832 — immunology — Posted on 2019-01-26

688 Genomes of a major nosocomial pathogen Enterococcus faecium are shaped by adaptive evolution of the chromosome and plasmidome

Arredondo-Alonso, S.; Top, J.; Schürch, A. C.; McNally, A.; Puranen, S.; Pesonen, M.; Pensar, J.; Marttinen, P.; Braat, J. C.; Rogers, M. R.; van Schaik, W.; Kaski, S.; Corander, J.; Willems, R. J.

10.1101/530725 — genomics — Posted on 2019-01-26

689 Genomic, Ancestral and Networking Analyses of a High-Altitude Native American Ecuadorian Patient with Congenital Insensitivity to Pain with Anhidrosis

Lopez-Cortes, A.; Zambrano, A. K.; Guevara-Ramirez, P.; Albuja Echeverria, B.; Guerrero, S.; Cabascango, E.; Perez-Villa, A.; Armendariz-Castillo, I.; Garcia-Cardenas, J.; Yumiceba, V.; Perez-M, G.; Leone, P. E.; Paz-y-Mino, C.

10.1101/529263 — genetics — Posted on 2019-01-26

690 Exploring Environmental Coverages of Species: A New Variable Selection Methodology for Rulesets from the Genetic Algorithm for Ruleset Prediction

Yang, A.; Gomez, J. P.; Blackburn, J.

10.1101/531079 — ecology — Posted on 2019-01-26

691 Computed Tomography Measures of Inter-site tumor Heterogeneity for Classifying Outcomes in High-Grade Serous Ovarian Carcinoma: a Retrospective Study

Veeraraghavan, H.; Vargas, H. A.; Sanchez, A. J.; Micco, M.; Mema, E.; Capanu, M.; Zheng, J.; Lakhman, Y.; Crispin-Ortuzar, M.; Huang, E.; Levine, D. A.; Deasy, J. O.; Snyder, A.; Miller, M. L.; Brenton, J. D.; Sala, E.

10.1101/531046 — bioinformatics — Posted on 2019-01-26

692 Fast and accurate long-read assembly with wtdbg2

Ruan, J.; Li, H.

10.1101/530972 — bioinformatics — Posted on 2019-01-26

693 Factorial Mendelian randomization: using genetic variants to assess interactions

Rees, J. M.; Foley, C. N.; Burgess, S.

10.1101/531228 — epidemiology — Posted on 2019-01-26

694 Causal relevance of obesity on the leading causes of death in women and men: A Mendelian randomization study

Censin, J. C.; Bovijn, J.; Ferreira, T.; Pulit, S. L.; Magi, R.; Mahajan, A.; Holmes, M. V.; Lindgren, C. M.

10.1101/523217 — epidemiology — Posted on 2019-01-26

695 Relation between prescribing of different antibiotics and rates of bacteremia/septicemia and associated mortality in the US and England

Goldstein, E.

10.1101/527101 — epidemiology — Posted on 2019-01-26

696 An evaluation of the Air Quality Health Index Program on respiratory diseases in Hong Kong: an interrupted time series analysis

Mason, T. G.; Linwei, T.; Schooling, C. M.; King Pan, C.

10.1101/529313 — epidemiology — Posted on 2019-01-26

697 Positive effects of low LDL-C and statins on bone mineral density: an integrated epidemiological observation analysis and Mendelian Randomization study

Li, G. H.-Y.; Cheung, C.-L.; Au, P. C.-M.; Tan, K. C.-B.; Wong, I. C.-K.; Sham, P.-C.

10.1101/531137 — epidemiology — Posted on 2019-01-26

698 Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging

Teo, J. X.; Davila, S.; Yang, C.; Pua, C. J.; Yap, J.; Tan, S. Y.; Sahlen, A.; Chin, C. W.-L.; Teh, B. T.; Rozen, S.; Cook, S.; Yeo, K. K.; Tan, P.; Lim, W. K.

10.1101/527077 — epidemiology — Posted on 2019-01-26

699 Do clinical investigations predict long-term outcome? A follow-up of paediatric respiratory outpatients

de Jong, C. C.; Pedersen, E. S.; Goutaki, M.; Trachsel, D.; Barben, J.; Kuehni, C. E.

10.1101/529537 — epidemiology — Posted on 2019-01-26

700 Identifying Severe Stroke Patients Likely to Benefit From Intervention Despite a Delay of a Day

Gonzalez, R. G.; Silva, G. S.; He, J.; Sadaghiani, S.; Wu, O.; Singhal, A. B.

10.1101/526947 — clinical trials — Posted on 2019-01-26

701 Neuroticism as a predictor of frailty in old age: a genetically informative approach

Danielsdottir, H. B.; Jylhava, J.; Hagg, S.; Lu, Y.; Colodro-Conde, L.; Martin, N. G.; Pedersen, N. L.; Mosing, M. A.; Lehto, K.

10.1101/527135 — epidemiology — Posted on 2019-01-26

702 Elevated serum aspartate aminotransferase levels concomitant with normal alanine aminotransferase levels in older low body weight people: Preliminary findings from a community-based epidemiological study

Shibata, M.; Nakajima, K.

10.1101/528034 — epidemiology — Posted on 2019-01-26

703 The native European Aedes geniculatus mosquito species can transmit Chikungunya virus

Prudhomme, J.; Fontaine, A.; LACOUR, G.; GANTIER, J.-C.; Diancourt, L.; Velo, E.; Bino, S.; Reiter, P.; Mercier, A.

10.1101/527382 — epidemiology — Posted on 2019-01-26

704 H7N6 Low Pathogenic Avian Influenza outbreak in commercial turkey farms in Chile caused by a native South American Lineage

Mathieu, C.; Gonzalez, A.; Garcia, A.; Johow, M.; Badia, C.; Jara, C.; Nunez, P.; Neira, V.; Montiel, N.; Killian, M. L.; Brito, B.

10.1101/527069 — epidemiology — Posted on 2019-01-26

705 Dietary intake and diet quality of Swiss adult survivors of childhood cancer compared to the general population

Belle, F. N.; Chatelan, A.; Kasteler, R.; Guessous, I.; Beck Popovic, M.; Ansari, M.; Kuehni, C.; Bochud, M.

10.1101/527424 — epidemiology — Posted on 2019-01-26

706 The pattern of Comorbidities and Associated Risk Factors among Colorectal Cancer Patients in Spain: CoMCoR study

LUQUE-FERNANDEZ, M. A.; Redondo-Sanchez, D.; RODRIGUEZ-BARRANCO, M.; Carmona Garcia, M. C.; Marcos-Gragera, R.; SANCHEZ-PEREZ, M. J.

10.1101/526673 — epidemiology — Posted on 2019-01-26

707 An inhomogeneous Poisson model of the spatial intensity of opioid overdoses, as represented by EMS naloxone use

Ryan, C.

10.1101/529206 — epidemiology — Posted on 2019-01-26

708 Hand-hygiene mitigation strategies against globaldisease spreading through the air transportationnetwork

Nicolaides, C.; Avraam, D.; Cueto-Felgueroso, L.; Gonzalez, M. C.; Juanes, R.

10.1101/530618 — epidemiology — Posted on 2019-01-26

709 Polygenic Risk for Alcohol Misuse is Moderated by Romantic Partnerships: Primarily in Men

Barr, P. B.; Kuo, S.; Aliev, F.; Latvala, A.; Viken, R.; Rose, R. J.; Kaprio, J.; Salvatore, J.; Dick, D.

10.1101/528844 — epidemiology — Posted on 2019-01-26

710 Effects of Large-Scale Oceanic Phenomena on Non-Cholera Vibriosis Incidence in the United States: Implications for Climate Change

Logar-Henderson, C.; Ling, R.; Tuite, A. R.; Fisman, D.

10.1101/528893 — epidemiology — Posted on 2019-01-26

711 Cassava planting material movement and grower behaviour in Zambia: implications for disease management

Szyniszewska, A. M.; Chikoti, P. C.; Tembo, M.; Mulenga, R.; van den Bosch, F.; McQuaid, C. F.

10.1101/528851 — epidemiology — Posted on 2019-01-26

712 Rice bran supplementation modulates growth, microbiome and metabolome in weaning infants: a clinical trial in Nicaragua and Mali

Zambrana, L. E.; McKeen, S. A.; Ibrahim, H. M.; Zarei, I.; Borreson, E. C.; Doumbia, L.; Bore, A.; Cissoko, A.; Douyon, S.; Kone, K.; Perez, J.; Perez, C.; Hess, A.; Abdo, Z.; Sangare, L.; Maiga, A.; Becker-Dreps, S.; Yuan, L.; Koita, O.; Vichez, S.; Ryan, E. P.

10.1101/530089 — clinical trials — Posted on 2019-01-26

713 Glycosylation of gigaxonin regulates intermediate filaments: Novel molecular insights into giant axonal neuropathy

CHEN, P.-H.; Smith, T.; Hu, J.; Pan, S.; Smith, A.; Lu, A.; Chi, J.-T.; Boyce, M.

10.1101/530303 — cell biology — Posted on 2019-01-26

714 A stochastic model of adult neurogenesis coupling cell cycle progression and differentiation

Stopka, A.; Boareto, M.

10.1101/530543 — neuroscience — Posted on 2019-01-26

715 Pure tones modulate the representation of orientation and direction in the primary visual cortex

McClure, J. P.; Polack, P.-O.

10.1101/531194 — neuroscience — Posted on 2019-01-26

716 Bayesian Multiple Emitter Fitting using Reversible Jump Markov Chain Monte Carlo

Fazel, M.; Wester, M. J.; Mazloom-Farsibaf, H.; Meddens, M. B. M.; Eklund, A.; Schlichthaerle, T.; Schueder, F.; Jungmann, R.; Lidke, K. A.

10.1101/530261 — biophysics — Posted on 2019-01-26

717 Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development

Krieger, T. G.; Moran, C. M.; Frangini, A.; Visser, W. E.; Schoenmakers, E.; Muntoni, F.; Clark, C.; Gadian, D.; Chong, W. K.; Kuczynski, A.; Dattani, M.; Lyons, G.; Efthymiadou, A.; Varga-Khadem, F.; Simons, B. D.; Chatterjee, K.; Livesey, F. J.

10.1101/529677 — developmental biology — Posted on 2019-01-26

718 Structural Determinants of Coiled Coil Mechanics

Lopez-Garcia, P.; Goktas, M.; Bergues-Pupo, A. E.; Koksch, B.; Varon Silva, D.; Blank, K. G.

10.1101/530873 — biophysics — Posted on 2019-01-26

719 Ncl1 mediated metabolic rewiring is critical during metabolic stress

Bhat, A.; Chakraborty, R.; Adlakha, K.; Agam, G.; Chakraborty, K.; Sengupta, S.

10.1101/529578 — biochemistry — Posted on 2019-01-26

720 MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine

Su, C.-C.; Klenotic, P.; Bolla, J. R.; Purdy, G.; Robinson, C.; Yu, E.

10.1101/531160 — biochemistry — Posted on 2019-01-26

721 Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry

Bishop, S. C.; Winefield, R.; Anbanandam, A.; Lampe, J. N.

10.1101/531087 — biochemistry — Posted on 2019-01-26

722 Precision Brain Morphometry: Feasibility and Opportunities of Extreme Rapid Scans

Nielsen, J. A.; Mair, R. W.; Baker, J. T.; Buckner, R. L.

10.1101/530436 — neuroscience — Posted on 2019-01-26

723 Inter-individual Variability of Functional Connectivity in Awake and Anesthetized Rhesus Monkeys

Xu, T.; Sturgeon, D.; Ramirez, J. S. B.; Froudist-Walsh, S.; Margulies, D. S.; Schroeder, C. E.; Fair, D. A.; Milham, M.

10.1101/531293 — neuroscience — Posted on 2019-01-26

724 Defining reprogramming checkpoints from single-cell analysis of induced pluripotency

Tran, K. A.; Pietrzak, S. J.; Zaidan, N. Z.; Siahpirani, A.; McCalla, S. G.; Iyer, G.; Roy, S.; Sridharan, R.

10.1101/531244 — developmental biology — Posted on 2019-01-26

725 Seeded propagation of alpha-synuclein aggregation in mouse brain using protein misfolding cyclic amplification

Nicot, S.; Verchere, J.; Belondrade, M.; Mayran, C.; Betemps, D.; Bougard, D.; Baron, T.

10.1101/530535 — neuroscience — Posted on 2019-01-26

726 Mechanistic insights into Zika virus NS3 helicase inhibition by Epigallocatechin-3-gallate

Kumar, D.; Sharma, N.; Aarthy, M.; Singh, S.; Giri, R.

10.1101/530600 — biochemistry — Posted on 2019-01-26

727 Sex and Estrous Cycle Effects on Anxiety- and Depression-related Phenotypes in Two-hit Developmental Stress Model

Jaric, I.; Rocks, D.; Cham, H.; Herchek, A.; Kundakovic, M.

10.1101/530311 — neuroscience — Posted on 2019-01-25

728 Prospective hippocampus and putamen activations support conditional memory-guided behavior

Hamm, A. G.; Mattfeld, A. T.

10.1101/530428 — neuroscience — Posted on 2019-01-25

729 Effects of transcranial alternating-current stimulation to secondary motor areas on cortical oscillations in stroke patients

Krawinkel, L. A.; Boenstrup, M.; Feldheim, J. F.; Schulz, R.; Backhaus, W.; Schneider, T. R.; Misselhorn, J.; Cheng, B.; Gerloff, C.

10.1101/529818 — neuroscience — Posted on 2019-01-25

730 Characterizing the dynamical complexity underlying meditation

Escrichs, A.; Sanjuan, A.; Atasoy, S.; Lopez-Gonzalez, A.; Garrido, C.; Camara, E.; Deco, G.

10.1101/521963 — neuroscience — Posted on 2019-01-25

731 Dissociation of broadband high-frequency activity and neuronal firing in the neocortex

Leszczynski, M.; Barczak, A.; Kajikawa, Y.; Ulbert, I.; Falchier, A.; Tal, I.; Haegens, S.; Melloni, L.; Knight, R.; Schroeder, C.

10.1101/531368 — neuroscience — Posted on 2019-01-25

732 Neural Coding of Gustatory Information in the Nucleus of the Solitary Tract in Lean and Obese Awake Freely-licking Rats

Weiss, M. S.; Hajnal, A.; Czaja, K.; Di Lorenzo, P. M.

10.1101/529792 — neuroscience — Posted on 2019-01-25

733 Fundamental contribution and host range determination of ANP32 protein family in influenza A virus polymerase activity

Zhang, H.; Zhang, Z.; Wang, Y.; Wang, M.; Wang, X.; Zhang, X.; Ji, S.; Du, C.; Chen, H.; Wang, X.

10.1101/529412 — microbiology — Posted on 2019-01-25

734 Novel Structural Features of Human Norovirus Capsid

Devant, J.; Hofhaus, G.; Hansman, G.

10.1101/528240 — microbiology — Posted on 2019-01-25

735 The two chemotaxis in Caulobacter crescentus operons play different roles in chemotaxis and biofilm regulation

Berne, C.; Brun, Y. V.

10.1101/528224 — microbiology — Posted on 2019-01-25

736 Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)

Kranzler, H.; Zhou, H.; Kember, R.; Smith, R. V.; Justice, A.; Damrauer, S.; Tsao, P. S.; Klarin, D.; Rader, D. J.; Cheng, Z.; Tate, J. P.; Becker, W. C.; Concato, J.; Xu, K.; Polimanti, R.; Zhao, H.; Gelernter, J.

10.1101/527929 — genetics — Posted on 2019-01-25

737 A multidisciplinary approach to a unique Palaeolithic human ichnological record from Italy (Basura Cave)

Romano, M.; CItton, P.; Salvador, I.; Arobba, D.; Rellini, I.; Firpo, M.; Negrino, F.; Zunino, M.; Starnini, E.; Avanzini, M.

10.1101/529404 — evolutionary biology — Posted on 2019-01-25

738 The cytoprotective role of antioxidants in mammalian cells under rapidly varying temperature, pressure and UV conditions during stratospheric balloon campaign

Kulbacka, J.; Przystupski, D.; Gorska, A.; Rozborska, P.; Bartosik, W.; Michel, O.; Rossowska, J.; Szewczyk, A.; Drag-Zalesinska, M.; Kasperkiewicz, P.; Gorski, J.

10.1101/526376 — cell biology — Posted on 2019-01-25

739 Regional fat depot masses are influenced by protein-coding gene variants

Neville, M. J.; Wittemans, L. B.; Pinnick, K. E.; Todorcevic, M.; Kaksonen, R.; Pietiläinen, K. H.; Luan, J.; Scott, R. A.; Wareham, N. J.; Langenberg, C.; Karpe, F.

10.1101/526434 — genomics — Posted on 2019-01-25

740 USP9X regulates DVL2 ubiquitylation to determine WNT pathway specification

Nielsen, C. P.; Jernigan, K. K.; Diggins, N.; Webb, D.; MacGurn, J. A.

10.1101/289595 — cell biology — Posted on 2019-01-25

741 Commonly used insect repellents hide human odors from Anopheles mosquitoes

Afify, A. J.; Betz, J. F.; Riabinina, O.; Potter, C. J.

10.1101/530964 — neuroscience — Posted on 2019-01-25

742 Sparse Binary Relation Representations for Genome Graph Annotation

Karasikov, M.; Mustafa, H.; Joudaki, A.; Javadzadeh-No, S.; Rätsch, G.; Kahles, A.

10.1101/468512 — bioinformatics — Posted on 2019-01-25

743 Meta-analysis of Alzheimer's disease brain transcriptomic data

Patel, H.; Dobson, R. J. B.; Newhouse, S. J.

10.1101/480459 — genetics — Posted on 2019-01-25

744 Genome-scale model of Rhodotorula toruloides metabolism

Tiukova, I. A.; Prigent, S.; Sandgren, M.; Nielsen, J.; Kerkhoven, E. J.

10.1101/528489 — systems biology — Posted on 2019-01-25

745 Sensory and auditory evoked responses mimic synchronization of cortical oscillations induced by Transcranial Magnetic Stimulation

Krawinkel, L. A.; Forisch, J.; Feldheim, J. F.; Backhaus, W.; Quandt, F.; Gerloff, C.

10.1101/525584 — neuroscience — Posted on 2019-01-25

746 miRNA activity contributes to accurate RNA splicing in C. elegans intestine and body muscle tissues.

Kotagama, K.; Schorr, A. L.; Steber, H. S.; Mangone, M.

10.1101/479832 — molecular biology — Posted on 2019-01-25

747 The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A)-translation

Hildebrandt, A.; Brüggemann, M.; Boerner, S.; Rückle, C.; Heidelberger, J. B.; Dold, A.; Busch, A.; Hänel, H.; Voigt, A.; Ebersberger, S.; Ebersberger, I.; Roignant, J.-Y.; Zarnack, K.; König, J.; Beli, P.

10.1101/516005 — molecular biology — Posted on 2019-01-25

748 \"Risk Factors for Visceral Leishmaniasis in Selected High Endemic Areas of Morang District, Nepal\": A case control Study

Mandal, P.; Wagle, R. R.; Thakur, A. K.; Uranw, S.; Ms.Punam Kumari Mandal,Dr.Rajendra Raj Wagle, Ms. Ajoy Kumar Thakur,Dr. Surendra Uranw,

10.1101/530741 — epidemiology — Posted on 2019-01-25

749 Meta-analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics

Lee, H.-J.; Kremer, D. M.; Sajjakulnukit, P.; Zhang, L.; Lyssiotis, C. A.

10.1101/509372 — bioinformatics — Posted on 2019-01-25

750 Neural circuitry of dialects through social learning in Drosophila.

Kacsoh, B. Z.; Bozler, J.; Hodge, S.; Bosco, G.

10.1101/511857 — neuroscience — Posted on 2019-01-25

751 Critical-Period Visual Deprivation Disrupts Binocular Integration but Spares Spatial Acuity in the Geniculocortical Pathway

Huh, C. Y. L.; Abdelaal, K.; Salinas, K. J.; Gu, D.; Zeitoun, J.; Figueroa Velez, D. X.; Peach, J. P.; Fowlkes, C. C.; Gandhi, S. P.

10.1101/484774 — neuroscience — Posted on 2019-01-25

752 Multi-trait meta-analyses reveal 25 quantitative trait loci for economically important traits in Brown Swiss cattle

Fang, Z.-H.; Pausch, H.

10.1101/517276 — genomics — Posted on 2019-01-25

753 Intra-species diversity ensures the maintenance of functional microbial communities under changing environmental conditions

Garcia-Garcia, N.; Tamames, J.; Linz, A. M.; Pedros-Alio, C.; Puente-Sanchez, F.

10.1101/530022 — ecology — Posted on 2019-01-25

754 Chronic, Low-Level Oral Exposure to Marine Toxin, Domoic Acid, Alters Whole Brain Morphometry in Nonhuman Primates

Petroff, R.; Richards, T.; Crouthamel, B.; McKain, N.; Stanley, C.; Grant, K. S.; Shum, S.; Jing, J.; Isoherranen, N.; Burbacher, T. M.

10.1101/439109 — pharmacology and toxicology — Posted on 2019-01-25

755 Subcortical Anatomy of the Default Mode Network: a functional and structural connectivity study

Alves, P. N.; Foulon, C.; Karolis, V.; Bzdok, D.; Margulies, D. S.; Volle, E.; Thiebaut de Schotten, M.

10.1101/528679 — neuroscience — Posted on 2019-01-25

756 Synchronization of sensory gamma oscillations promotes multisensory communication

Misselhorn, J.; Schwab, B. C.; Schneider, T. R.; Engel, A. K.

10.1101/523688 — neuroscience — Posted on 2019-01-25

757 Behavioral state-dependent lateralization of dorsal dentate gyrus c-Fos expression in mice

Jordan, J. T.; Shanley, M. R.; Pytte, C. L.

10.1101/214239 — neuroscience — Posted on 2019-01-25

758 Spatial and feature-selective attention have distinct effects on population-level tuning.

Goddard, E.; Carlson, T. A.; Woolgar, A.

10.1101/530352 — neuroscience — Posted on 2019-01-25

759 Biomedical Concept Recognition Using Deep Neural Sequence Models

Hailu, N. D.; Bada, M.; Hadgu, A. T.; Hunter, L. E.

10.1101/530337 — bioinformatics — Posted on 2019-01-25

760 Baltic Methanosarcina and Clostridium compete for electrons from metallic iron

Jaramillo, P. A. P.; Snoeyenbos-West, O.; Loescher, C.; Thamdrup, B.; Rotaru, A.-E.

10.1101/530386 — microbiology — Posted on 2019-01-25

761 Visualization and analysis of high-throughput in vitro dose-response datasets with Thunor

Lubbock, A. L. R.; Harris, L. A.; Quaranta, V.; Tyson, D. R.; Lopez, C. F.

10.1101/530329 — pharmacology and toxicology — Posted on 2019-01-25

762 3.5KJPNv2, An allele frequency panel of 3,552 Japanese Individuals

Tadaka, S.; Katsuoka, F.; Ueki, M.; Kojima, K.; Makino, S.; Saito, S.; Otsuki, A.; Gocho, C.; Sakurai-Yageta, M.; Danjo, I.; Motoike, I. N.; Yamaguchi-Kabata, Y.; Shirota, M.; Koshiba, S.; Nagasaki, M.; Minegishi, N.; Hozawa, A.; Kuriyama, S.; Shimizu, A.; Yasuda, J.; Fuse, N.; The Tohoku Medical Megabank Project Study Group, ; Tamiya, G.; Yamamoto, M.; Kinoshita, K.

10.1101/529529 — genomics — Posted on 2019-01-25

763 Erroneous inference based on a lack of preference within one group: autism, mice, and the Social Approach Task.

Nygaard, K. R. R.; Maloney, S. E. E.; Dougherty, J. D.

10.1101/530279 — animal behavior and cognition — Posted on 2019-01-25

764 Cross-reactivity of a rice NLR immune receptor to distinct effectors from the blast pathogen leads to partial disease resistance

Varden, F. A.; Saitoh, H.; YOSHINO, K.; Franceschetti, M.; Kamoun, S.; Terauchi, R.; Banfield, M. J.

10.1101/530675 — plant biology — Posted on 2019-01-25

765 Identification of frequent activating HER2 mutations in primary canine pulmonary adenocarcinoma

Lorch, G.; Sivaprakasam, K.; Zismann, V.; Perdigones, N.; Contente-Cuomo, T.; Nazareno, A.; Facista, S.; Wong, S.; Liang, W. S.; Amann, J. M.; Sinicropi-Yao, S. L.; Koenig, M. J.; La Perle, K.; Whitsett, T. G.; Murtaza, M.; Trent, J.; Carbone, D. P.; Hendricks, W. P. D.

10.1101/528182 — cancer biology — Posted on 2019-01-25

766 On the innovation and evolution of predatory tactics

Gokhale, C. S.; Wignall, A. E.

10.1101/530238 — animal behavior and cognition — Posted on 2019-01-25

767 Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community

Hart, S. F.; Pineda, J. M. B.; Chen, C.-C.; Green, R.; Shou, W.

10.1101/530287 — microbiology — Posted on 2019-01-25

768 Identification and characterization of a novel pic gene cluster responsible for picolinic acid degradation in Alcaligenes faecalis JQ135

Qiu, J.; Zhao, L.; Xu, S.; Chen, Q.; Chen, L.; Liu, B.; Hong, Q.; Lu, Z.; He, J.

10.1101/530550 — microbiology — Posted on 2019-01-25

769 mtDNA recombination indicative of hybridization suggests a role of the mitogenome in the adaptation of reef building corals to extreme environments

Banguera-Hinestroza, E.; Sawall, Y.; Al-Sofyani, A.; Mardulyn, P.; Fuertes-Aguilar, J.; Cardenas-Henao, H.; Jimenez-Infante, F.; Voolstra, C. R.; Flot., J.-F.

10.1101/462069 — evolutionary biology — Posted on 2019-01-25

770 The microstructure of laminin-111 compensates for dystroglycan loss in functional differentiation of mammary epithelial cells

Kent, A. J.; Mayer, N.; Inman, J. L.; Hochman-Mendez, C.; Bissell, M. J.; Robertson, C.

10.1101/531053 — bioengineering — Posted on 2019-01-25

771 Classifying Non-Small Cell Lung Cancer Histopathology Types and Transcriptomic Subtypes using Convolutional Neural Networks

Yu, K.-H.; Wang, F.; Berry, G. J.; Re, C.; Altman, R. B.; Snyder, M.; Kohane, I. S.

10.1101/530360 — pathology — Posted on 2019-01-25

772 Surprising threats accelerate evidence accumulation for conscious perception

McFadyen, J.; Smout, C.; Tsuchiya, N.; Mattingley, J. B.; Garrido, M. I.

10.1101/525519 — neuroscience — Posted on 2019-01-25

773 Elevation of FAM129A in neutrophils exposed to serum of patients with severe sepsis: in silico investigations during a hands on training workshop and follow on validation of protein expression in neutrophils

Roelands, J.; Chiche, L.; Marches, R.; Toufiq, M.; Kabeer, B. A.; Alfaki, M. A. I.; Saadaoui, M.; Lakshmanan, A. P.; Bangarusamy, D. K.; Murugesan, S.; Bedognetti, D.; Hendrickx, W.; Khodor, S. A.; Terranegra, A.; Banchereau, J.; Garand, M.; Chaussabel, D.; Rinchai, D.

10.1101/529446 — immunology — Posted on 2019-01-25

774 Deep learning enables accurate clustering and batch effect removal in single-cell RNA-seq analysis

Li, X.; Lyu, Y.; Park, J.; Zhang, J.; Stambolian, D.; Susztak, K.; Hu, G.; Li, M.

10.1101/530378 — genomics — Posted on 2019-01-25

775 Mitochondrial volume fraction controls translation of nuclear-encoded mitochondrial proteins

Tsuboi, T.; Viana, M. P.; Xu, F.; Yu, J.; Chanchani, R.; Arceo, X. G.; Tutucci, E.; Choi, J.; Chen, Y. S.; Singer, R. H.; Rafelski, S. M.; Zid, B. M.

10.1101/529289 — cell biology — Posted on 2019-01-25

776 Behavioral state-dependent lateralization of dorsal dentate gyrus c-Fos expression in mice

Jordan, J. T.; Shanley, M. R.; Pytte, C. L.

10.1101/214239 — neuroscience — Posted on 2019-01-25

777 Adaption of artificial microvascular networks

Fredrich, T.; Welter, M.; Rieger, H.

10.1101/429027 — cancer biology — Posted on 2019-01-25

778 RadiationGeneSigDB: A database of oxic and hypoxic radiation response gene signatures and their utility in identification of hypoxia-regulated MicroRNA

Manem, V.; Dhawan, A.

10.1101/455345 — bioinformatics — Posted on 2019-01-25

779 Codon clusters with biased synonymous codon usage represent hidden functional domains in protein-coding DNA sequences

Peng, Z.; Ben-Shahar, Y.

10.1101/530345 — bioinformatics — Posted on 2019-01-25

780 Hydrophobic organic contaminants are not linked to microplastic uptake in Baltic Sea herring

Ogonowski, M.; Wenman, V.; Barth, A.; Hamacher-Barth, E.; Danielsson, S.; Gorokhova, E.

10.1101/363127 — pharmacology and toxicology — Posted on 2019-01-25

781 Anticipated ITD statistics are built into human sound localization

Pavao, R.; Sussman, E.; Fischer, B.; Pena, J.

10.1101/303347 — neuroscience — Posted on 2019-01-25

782 Imperfect Bayesian inference in visual perception

Stengard, E.; van den Berg, R.

10.1101/402776 — neuroscience — Posted on 2019-01-25

783 Potential involvement of root auxins in drought tolerance by modulating nocturnal and daytime water use in wheat

Sadok, W.; Schoppach, R.

10.1101/530246 — plant biology — Posted on 2019-01-25

784 Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia

Tkatchenko, T. V.; Shah, R. L.; Nagasaki, T.; Tkatchenko, A. V.

10.1101/530766 — genetics — Posted on 2019-01-25

785 Novel Insights into Malaria Vector Surveillance in Madagascar Using a Quadrant Enabled Screen Trap (QUEST) and Bloodmeal Detection Assay for Regional Transmission (BLOODART)

Tedrow, R. E.; Rakotomanga, T.; Nepomichene, T.; Ratovonjato, J.; Ratsimbasoa, A.; Svenson, G. J.; Zimmerman, P.

10.1101/530758 — ecology — Posted on 2019-01-25

786 A novel statistical method to mining the suspicious lethal genes and mutation sites by abnormal distributions of SNP patterns

ding, x.

10.1101/530733 — bioinformatics — Posted on 2019-01-25

787 Gametic specialization of centromeric histone paralogs in Drosophila virilis

Kursel, L. E.; Malik, H. S.

10.1101/530295 — cell biology — Posted on 2019-01-25

788 Leveraging tissue specific gene expression regulation to identify genes associated with complex diseases

Liu, W.; Li, M.; Zhang, W.; Zhou, G.; Wu, X.; Wang, J.; Zhao, H.

10.1101/529297 — genetics — Posted on 2019-01-25

789 Single-cell transcriptome provides novel insights into antler stem cells, a cell type capable of mammalian organ regeneration

Ba, H.; Wang, D.; Wu, W.; Sun, H.; Li, C.

10.1101/263798 — cell biology — Posted on 2019-01-25

790 Beyond synthetic lethality: charting the landscape of clinically relevant genetic interactions in cancer

Magen, A.; Das, A.; Sang Lee, J.; Sharmin, M.; Lugo, A.; Gutkind, J. S.; Schaffer, A. A.; Ruppin, E.; Hannenhalli, S.

10.1101/253120 — systems biology — Posted on 2019-01-24

791 Euchromatic histone methyltransferases regulate peripheral heterochromatin tethering via histone and non-histone protein methylations

Rao, R. A.; Ketkar, A. A.; Kedia, N.; Krishnamoorthy, V. K.; Lakshmanan, V.; Kumar, P.; Mohanty, A.; Kumar, S.; Raja, S. O.; Gulyani, A.; Chaturvedi, C.; Brand, M.; Palakodeti, D.; Rampalli, S.

10.1101/240952 — molecular biology — Posted on 2019-01-24

792 Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage

Li, Z.-R.; Li, J.; Cai, W.; Lai, J.; McKinnie, S.; Zhang, W.-P.; Moore, B.; Zhang, W.; Qian, P.-Y.

10.1101/530204 — microbiology — Posted on 2019-01-24

793 Subcortical Anatomy of the Default Mode Network: a functional and structural connectivity study

Alves, P. N.; Foulon, C.; Karolis, V.; Bzdok, D.; Margulies, D. S.; Volle, E.; Thiebaut de Schotten, M.

10.1101/528679 — neuroscience — Posted on 2019-01-24

794 De novo assembly of the Mongolian gerbil genome and transcriptome

Cheng, S.; Fu, Y.; Zhang, Y.; Xian, W.; Wang, H.; Grothe, B.; Lu, X.; Xu, X.; Klug, A.; McCullagh, E. A.

10.1101/522516 — genomics — Posted on 2019-01-24

795 Endogenous insulin contributes to pancreatic cancer development

Zhang, A. M.; Magrill, J.; de Winter, T. J. J.; Hu, X.; Skovso, S.; Schaeffer, D. F.; Kopp, J. L.; Johnson, J. D.

10.1101/530097 — cancer biology — Posted on 2019-01-24

796 Worldwide impacts of humans on animal genetic diversity

Millette, K. L.; Fugere, V.; Debyser, C.; Greiner, A.; Chain, F. J. J.; Gonzalez, A.

10.1101/527739 — evolutionary biology — Posted on 2019-01-24

797 Computational Analysis Revealed Five Novel Mutations in Human IL2RG gene Related to X-SCID

Abbas, T. B.; Hassan, A. A.; Abdelgadir, A. E.; Mohammed, W. O.; Abdelhameed, T. A.; Hassan, M. A.

10.1101/528349 — bioinformatics — Posted on 2019-01-24

798 Velocity estimation in reinforcement learning

Velazquez, C.; Villarreal, M.; Bouzas, A.

10.1101/432492 — animal behavior and cognition — Posted on 2019-01-24

799 A rapid method for DNA extraction of cotton mature fiber suitable for PCR fingerprinting

Ibrahim, S. D.; Alsamman, A. M.; Kahlifa, K.

10.1101/529305 — genomics — Posted on 2019-01-24

800 Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, L. R.; Zeng, J.; Sidorenko, J.; Yengo, L.; Moser, G.; Kemper, K. E.; Wang, H.; Zheng, Z.; Magi, R.; Esko, T.; Metspalu, A.; Wray, N. R.; Goddard, M. E.; Yang, J.; Visscher, P. M.

10.1101/522961 — genetics — Posted on 2019-01-24

801 C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

Sowamber, R.; Chehade, R.; Bitar, M.; Dodds, L.; Milea, A.; Shaw, P.; George, S. H.

10.1101/528885 — cancer biology — Posted on 2019-01-24

802 Limits on visual awareness of object targets in the context of other object category masks: Investigating bottlenecks in the continuous flash suppression paradigm with hand and tool stimuli

Zopf, R.; Schweinberger, S. R.; Rich, A. N.

10.1101/363515 — neuroscience — Posted on 2019-01-24

803 Single-cell transcriptome provides novel insights into antler stem cells, a cell type capable of mammalian organ regeneration

Ba, H.; Wang, D.; Wu, W.; Sun, H.; Li, C.

10.1101/263798 — cell biology — Posted on 2019-01-24

804 Empirical and Computational Comparison of Alternative Therapeutic Exon Skip Repairs for Duchenne Muscular Dystrophy

Ma, K. M.; Thomas, E. S.; Wereszczynski, J.; Menhart, N.

10.1101/527705 — biophysics — Posted on 2019-01-24

805 Excess neuronal branching allows for innervation of specific dendritic compartments in cortex

Bird, A. D.; Deters, L. H.; Cuntz, H.

10.1101/529875 — neuroscience — Posted on 2019-01-24

806 New Asgard archaea capable of anaerobic hydrocarbon cycling

Seitz, K. W.; Dombrowski, N.; Eme, L.; Spang, A.; Lombard, J.; Sieber, J. R.; Teske, A. P.; Ettema, T. J. G.; Baker, B. J.

10.1101/527697 — microbiology — Posted on 2019-01-24

807 Molecular Biology Information Service: An innovative medical library-based bioinformatics support service for biomedical researchers

Chattopadhyay, A.; Iwema, C. L.; Epstein, B. A.; Lee, A. V.; Levine, A. S.

10.1101/530071 — bioinformatics — Posted on 2019-01-24

808 Overcoming insecticide resistance through computational inhibitor design

Correy, G.; Zaidman, D.; Harmelin, A.; Carvalho, S.; Mabbitt, P. D.; Calaora, V.; James, P. J.; Kotze, A. C.; London, N.; Jackson, C. J.

10.1101/161430 — biochemistry — Posted on 2019-01-24

809 Comammox bacteria are dominant ammonia oxidizers in tertiary rotating biological contactors of a municipal wastewater treatment plant

Spasov, E.; Tsuji, J. M.; Hug, L. A.; Doxey, A. C.; Sauder, L. A.; Parker, W. J.; Neufeld, J. D.

10.1101/529826 — microbiology — Posted on 2019-01-24

810 Oscillatory Mechanisms of Successful Memory Formation in Younger and Older Adults Are Related to Structural Integrity

Sander, M. C.; Fandakova, Y.; Grandy, T. H.; Shing, Y. L.; Werkle-Bergner, M.

10.1101/530121 — neuroscience — Posted on 2019-01-24

811 Functional potential of bacterial strains in the premature infant gut microbiome is associated with gestational age

Rahman, S. F.; Olm, M. R.; Morowitz, M. J.; Banfield, J. F.

10.1101/530139 — microbiology — Posted on 2019-01-24

812 Huntington's disease onset is determined by length of uninterrupted CAG, not encoded polyglutamine, and is modified by DNA maintenance mechanisms

Genetic Modifiers of Huntington's Disease (GeM-HD) Consortium, ; Lee, J.-M.; Correia, K.; Loupe, J.; Kim, K.-H.; Barker, D.; Hong, E. P.; Chao, M. J.; Long, J. D.; Lucente, D.; Vonsattel, J.-P.; Mouro Pinto, R.; Abu Elneel, K.; Ramos, E. M.; Mysore, J. S.; Gillis, T.; Wheeler, V. C.; MacDonald, M. E.; Gusella, J. F.; Massey, T.; McAllister, B.; Medway, C.; Stone, T. C.; Hall, L.; Jones, L.; Holmans, P.; Kwak, S.; Ehrhardt, A.; Sampaio, C.; Ciosi, M.; Maxwell, A.; Chatzi, A.; Monckton, D. G.; Orth, M.; Landwehrmeyer, G. B.; Paulsen, J. S.; Dorsey, E. R.; Shoulson, I.; Myers, R. H.

10.1101/529768 — genetics — Posted on 2019-01-24

813 BioID based proteomic screen identifies VDAC2 as a coordinator of Bid dependent apoptotic priming during mitosis.

Pedley, R.; King, L.; Mallikarjun, V.; Wang, P.; Swift, J.; Brennan, K.; Gilmore, A. P.

10.1101/529685 — cell biology — Posted on 2019-01-24

814 Preliminary evidence for altered interoceptive processing in smokers.

Todd, J.; Hina, F.; Aspell, J.

10.1101/529842 — physiology — Posted on 2019-01-24

815 PSMC3 is required for spermatogonia niche establishment in mouse spermatogenesis

Pranchevicius, M. C.; Previato, L.; O. de Castro, R.; Pezza, R. J.

10.1101/529149 — developmental biology — Posted on 2019-01-24

816 FISIK: Framework for the Inference of in Situ Interaction Kinetics from single-molecule imaging data

de Oliveira, L. R.; Jaqaman, K.

10.1101/530063 — biophysics — Posted on 2019-01-24

817 Transfer Learning From Nucleus Detection To Classification In Histopathology Images

Yousefi, S.; Nie, Y.

10.1101/530113 — bioinformatics — Posted on 2019-01-24

818 Sensory and auditory evoked responses mimic synchronization of cortical oscillations induced by Transcranial Magnetic Stimulation

Krawinkel, L. A.; Forisch, J.; Feldheim, J. F.; Backhaus, W.; Quandt, F.; Gerloff, C.

10.1101/525584 — neuroscience — Posted on 2019-01-24

819 Chemogenetic inhibition of a monosynaptic projection from the basolateral amygdala to the ventral hippocampus reduces appetitive and consummatory alcohol drinking behaviors

Ewin, S. E.; Almonte, A. G.; Heaney, C. F.; Chappell, A. M.; Raab-Graham, K. F.; Weiner, J. L.

10.1101/529719 — neuroscience — Posted on 2019-01-24

820 Spread of pathological α-synuclein from urogenital nerves initiates multiple system atrophy-like symptoms

Ding, X.; Wang, X.; Ma, M.; Wu, E.; Teng, D.; Yuan, X.; Zhou, L.; Zhang, R.; Yao, J.; Chen, Y.; Xia, D.; Teng, R. K. F.; Wang, F.; Huang, J. H.; Yue, Z.; Zhang, Z.; Teng, J.; Tang, B.

10.1101/529594 — neuroscience — Posted on 2019-01-24

821 Spatial proximity determines post-speciation introgression in Solanum

Hamlin, J.; Moyle, L. C.

10.1101/529115 — evolutionary biology — Posted on 2019-01-24

822 LAmbDA: Label Ambiguous Domain Adaption Dataset Integration Reduces Batch Effects and Improves Subtype Detection

Johnson, T.; Huang, Z.; Yu, C.; Wang, T.; Wu, Y.; Han, Y.; Huang, K.; Zhang, J.

10.1101/522474 — bioinformatics — Posted on 2019-01-24

823 Anomalous Perception Of Biological Motion In Autism: A Conceptual Review And Meta-Analysis

Federici, A.; Parma, V.; Vicovaro, M.; Radassao, L.; Casartelli, L.; Ronconi, L.

10.1101/530030 — neuroscience — Posted on 2019-01-24

824 RNA interactions with CTCF are essential for its proper function

Saldana-Meyer, R.; Rodriguez-Hernaez, J.; Nishana, M.; Jacome-Lopez, K.; Nora, E. P.; Bruneau, B. G.; Furlan-Magaril, M.; Skok, J.; Reinberg, D.

10.1101/530014 — molecular biology — Posted on 2019-01-24

825 Genome-scale model of Rhodotorula toruloides metabolism

Tiukova, I. A.; Prigent, S.; Sandgren, M.; Nielsen, J.; Kerkhoven, E. J.

10.1101/528489 — systems biology — Posted on 2019-01-24

826 Social context and dominance status contribute to sleep patterns and quality in groups of freely-moving mice

Karamihalev, S.; Flachskamm, C.; Kimura, M.; Chen, A.

10.1101/529669 — neuroscience — Posted on 2019-01-24

827 Removal of Spo11 from meiotic DNA breaks in vitro but not in vivo by Tyrosyl DNA Phosphodiesterase 2

Johnson, D.; Allison, R. M.; Cannavo, E.; Cejka, P.; Neale, M. J.

10.1101/527333 — molecular biology — Posted on 2019-01-24

828 Intra-species diversity ensures the maintenance of functional microbial communities under changing environmental conditions

Garcia-Garcia, N.; Tamames, J. M.; Linz, A.; Pedros-Alio, C.; Puente-Sanchez, F.

10.1101/530022 — ecology — Posted on 2019-01-24

829 Bioshake: a Haskell EDSL for bioinformatics pipelines

Bedo, J.

10.1101/529479 — bioinformatics — Posted on 2019-01-24

830 ApicoTFdb: The comprehensive web repository of apicomplexan transcription factors and regulators.

Sardar, R.; Kaushik, A.; Pandey, R.; Mohmmed, A.; Ali, S.; Gupta, D.

10.1101/530006 — bioinformatics — Posted on 2019-01-24

831 Robust taxonomic classification of uncharted microbial sequences and bins with CAT and BAT

von Meijenfeldt, F. A. B.; Arkhipova, K.; Cambuy, D. D.; Coutinho, F. H.; Dutilh, B. E.

10.1101/530188 — bioinformatics — Posted on 2019-01-24

832 Ionic strength and calcium regulate the membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero

Raasakka, A.; Jones, N. C.; Hoffmann, S. V.; Kursula, P.

10.1101/529586 — biochemistry — Posted on 2019-01-24

833 Targeting extracellular glycans: Tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

Guy, C. S.; Gibson, M. I.; Fullam, E.

10.1101/529743 — biochemistry — Posted on 2019-01-24

834 Measuring directed functional connectivity in neural data using Non-Parametric Directionality Analysis: validation and comparison with Non-Parametric Granger Causality

West, T. O.; Halliday, D. M.; Bressler, S.; Farmer, S. F.; Litvak, V.

10.1101/526566 — neuroscience — Posted on 2019-01-24

835 PPARβ/δ controls Mediator recruitment and transcription initiation

Legrand, N.; Bretscher, C. L.; Zielke, S.; Wilke, B.; Daude, M.; Fritz, B.; Diederich, W. E.; Adhikary, T.

10.1101/525576 — molecular biology — Posted on 2019-01-24

836 Frequency dependent responses of neuronal models to oscillatory inputs in current versus voltage clamp

Rotstein, H. G.; Nadim, F.

10.1101/515510 — neuroscience — Posted on 2019-01-24

837 Modulation of large-scale cortical coupling by transcranial alternating current stimulation

Schwab, B. C.; Misselhorn, J.; Engel, A. K.

10.1101/484014 — neuroscience — Posted on 2019-01-24

838 Discovering human transcription factor interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays

Shrestha, S.; Sewell, J. A.; Santoso, C. S.; Forchielli, E.; Carrasco Pro, S.; Martinez, M.; Fuxman Bass, J. I.

10.1101/459305 — genomics — Posted on 2019-01-24

839 Individual variability in behavior and functional networks predicts vulnerability using a predator scent model of PTSD

Dopfel, D.; Perez, P. D.; Verbitsky, A.; Bravo-Rivera, H.; Ma, Y.; Quirk, G. J.; Zhang, N.

10.1101/438952 — neuroscience — Posted on 2019-01-24

840 Context-based facilitation in visual word recognition: Evidence for visual and lexical but not pre-lexical contributions

Eisenhauer, S.; Fiebach, C. J.; Gagl, B.

10.1101/410795 — neuroscience — Posted on 2019-01-24

841 Genome plasticity in Papillomaviruses and de novo emergence of E5 oncogenes

Felez-Sanchez, M.; Willemsen, A.; Bravo, I. G.

10.1101/337477 — evolutionary biology — Posted on 2019-01-24

842 Learning the sequence of influenza A genome assembly during viral replication using point process models and fluorescence in situ hybridization

Majarian, T. D.; Murphy, R. F.; Lakdawala, S.

10.1101/322966 — bioinformatics — Posted on 2019-01-24

843 Acute physical exercise of moderate intensity improves memory consolidation in humans via BDNF and endocannabinoid signaling

Marin Bosch, B.; Bringard, A.; Logrieco, M. G.; Lauer, E.; Imobersteg, N. M.; Ferretti, G.; Thomas, A.; Schwartz, S.; Igloi, K.

10.1101/211227 — neuroscience — Posted on 2019-01-24

844 Medial orbitofrontal cortex, dorsolateral prefrontal cortex, and hippocampus differentially represent the event saliency

Jafarpour, A.; Griffin, S.; Lin, J. J.; Knight, R. T.

10.1101/285718 — neuroscience — Posted on 2019-01-24

845 VSIM: Visualization and simulation of variants in personal genomes with an application to premarital testing

Althagafi, A. T.; Hoehndorf, R.

10.1101/529461 — bioinformatics — Posted on 2019-01-24

846 Buffer Therapy in Acute Metabolic Acidosis: Effects on Acid-Base Status and Glomerular Permeability

Schnapauff, J.; Piros, D.; Rippe, A.; Bentzer, P.; Clyne, N.; Oberg, C. M.

10.1101/528521 — physiology — Posted on 2019-01-24

847 FabriEVEs: A dedicated platform for endogenous viral elements in fishes, amphibians, birds, reptiles and invertebrates

Zhong, J.; Zhu, J.; Xu, Z.; Zou, G.; Zhao, J.; Jiang, S.; Zhang, W.; Xia, J.; Yang, L.; Li, F.; Gao, Y.; Chen, F.; Wu, Y.; Chen, D.

10.1101/529354 — evolutionary biology — Posted on 2019-01-24

848 Nanoparticle Mediated NADPH Regeneration for Enhanced Ethanol Production by Engineered Synechocystis sp. PCC 6803

Velmurugan, R.; Incharoensakdi, A.

10.1101/529420 — bioengineering — Posted on 2019-01-24

849 Fundamental contribution and host range determination of ANP32 protein family in influenza A virus polymerase activity

Zhang, H.; Zhang, Z.; Wang, Y.; Wang, M.; Wang, X.; Zhang, X.; Ji, S.; Du, C.; Chen, H.; Wang, X.

10.1101/529412 — microbiology — Posted on 2019-01-24

850 Asymmetry in marginal population performance foreshadows widespread species range shifts

Pulido, F.; Castagneyrol, B.; Rodriguez-Sanchez, F.; Caceres, Y.; Pardo, A.; Moracho, E.; Kollmann, J.; Valladares, F.; Ehrlen, J.; Jump, A. S.; Svenning, J.-C.; Hampe, A.

10.1101/529560 — ecology — Posted on 2019-01-24

851 On measuring selection in cancer from subclonal mutation frequencies

Bozic, I.; Paterson, C.; Waclaw, B.

10.1101/529396 — cancer biology — Posted on 2019-01-24

852 tealeaves: an R package for modelling leaf temperature using energy budgets

Muir, C. D.

10.1101/529487 — plant biology — Posted on 2019-01-24

853 Cranial Bone Growth in Isolated Sagittal Craniosynostosis Compared to Normal Growth in the First Six Months of Age

Mercan, E.; Hopper, R.; Maga, A. M.

10.1101/528869 — physiology — Posted on 2019-01-24

854 Prion-like spreading of Alzheimer's disease within the brain's connectome

Fornari, S.; Schafer, A.; Jucker, M.; Goriely, A.; Kuhl, E.

10.1101/529438 — neuroscience — Posted on 2019-01-24

855 Simultaneous quantification of protein-DNA contacts and transcriptomes in single cells

Rooijers, K.; Markodimitraki, C.; Rang, F.; de Vries, S.; Chialastri, A.; de Luca, K.; Mooijman, D.; Dey, S.; kind, j.

10.1101/529388 — molecular biology — Posted on 2019-01-24

856 The genomic architecture of introgression amongsibling species of bacteria

Cavassim, M. I. A.; Moeskjaer, S.; Moslemi, C.; Fields, B.; Bachmann, A.; Vilhjalmsson, B.; Schierup, M. H.; Young, J. P. W.; Andersen, S. U.

10.1101/526707 — genomics — Posted on 2019-01-24

857 Identification of 12 cancer types through genome deep learning

Sun, Y.; Zhu, S.; Ma, K.; Liu, W.; Yue, Y.; Hu, G.; Lu, H.; Chen, W.

10.1101/528216 — bioinformatics — Posted on 2019-01-24

858 Resting state fMRI reveals differential effects of glucose administration on central appetite signalling in young and old adults

Peters, R.; White, D. J.; Scholey, A.

10.1101/529552 — neuroscience — Posted on 2019-01-24

859 Diffusional and chemical control in the tyrosine kinase network of platelet CLEC-2 signalling

Martyanov, A.; Balabin, F. A.; Dunster, J. L.; Panteleev, M. A.; Gibbins, J.; Sveshnikova, A. N.

10.1101/529859 — systems biology — Posted on 2019-01-24

860 P-glycoprotein Detoxification by the Malpighian Tubules of the Desert Locust

Rossi, M.; De Battisti, D.; Niven, J. E.

10.1101/529750 — physiology — Posted on 2019-01-24

861 Redefining the medicago sativa alphapartitivirus genome sequences

Bejerman, N.; Debat, H.; Trucco, V.; de Breuil, S.; Lenardon, S.; Giolitti, F.

10.1101/529610 — microbiology — Posted on 2019-01-24

862 Selection for antibiotic resistance is reduced when embedded in a natural microbial community

Klümper, U.; Recker, M.; Zhang, L.; Yin, X.; Zhang, T.; Buckling, A.; Gaze, W.

10.1101/529651 — microbiology — Posted on 2019-01-24

863 Carbs versus fat: does it really matter for maintaining lost weight?

Hall, K. D.; Guo, J.

10.1101/476655 — physiology — Posted on 2019-01-24

864 Intracortical neural activity distal to seizure-onset-areas predicts human focal seizures

Proix, T.; Aghagolzadeh, M.; Madsen, J. R.; Cosgrove, R.; Eskandar, E.; Hochberg, L. R.; Cash, S. S.; Truccolo, W.

10.1101/529966 — neuroscience — Posted on 2019-01-24

865 Using long-read sequencing to detect imprinted DNA methylation

Gigante, S.; Gouil, Q.; Lucattini, A.; Keniry, A.; Beck, T.; Tinning, M.; Gordon, L.; Woodruff, C.; Speed, T. P.; Blewitt, M.; Ritchie, M.

10.1101/445924 — genomics — Posted on 2019-01-24

866 Predicting diabetes second-line therapy initiation in the Australian population via timespan-guided neural attention network

Fiorini, S.; Hajati, F.; Barla, A.; Girosi, F.

10.1101/529933 — bioengineering — Posted on 2019-01-24

867 Oscillations, criticality and responsiveness in complex brain networks

Kim, M.; Lee, U.

10.1101/529982 — neuroscience — Posted on 2019-01-24

868 Effects of 7,8-dihydroxycoumarin on the Myelin Morphological Changes and PSD-95 Protein Expression in Balb/c Mice after Sciatic Nerve Injury

Cao, J.; Zhang, L.; Li, J.; Leng, H.

10.1101/529917 — neuroscience — Posted on 2019-01-24

869 Cold Shock Fail to Restrain Pre-formed Vibrio parahaemolyticus Biofilm

Zhao, Y.; Yu, W.; Han, Q.; Song, X.; Fu, J.; Liu, H.; Guo, Z.; Malakar, P. K.; Pan, Y.

10.1101/529925 — microbiology — Posted on 2019-01-24

870 Epidemiology of Staphylococcus aureus in Neonates on Admission to a Chinese Neonatal Intensive Care Unit

Geng, W.; Qi, Y.; Li, W.; McConvillle, T. H.; Ricciuti, A. H.; Grohs, E.; Saiman, L.; Uhlemann, A.-C.

10.1101/529941 — microbiology — Posted on 2019-01-24

871 Effects of flavorless electronic cigarette aerosol on the survival and growth of common oral commensal streptococci

Cuadra, G.; Smith, M.; Nelson, J. M.; Loh, E.; Palazzolo, D.

10.1101/529909 — microbiology — Posted on 2019-01-24

872 Bacterial and Archaeal Communities in Recycling Effluents from a Bauxite Flotation Plant

LIU, X. x.; Wu, Y.; Liu, X.; Wu, H.; Xie, J.; Wang, G.; Qiu, G.; Huo, Q.

10.1101/529958 — microbiology — Posted on 2019-01-24

873 Long-term fish assemblages of the Ohio River: altered trophic and life history strategies with hydrologic alterations and landuse modifications

Pyron, M.; Mims, M.; Minder, M. M.; Shields, R. C.; Chodkowski, N.; Artz, C. C.

10.1101/529974 — ecology — Posted on 2019-01-24

874 The impact of coregistration of gradient recalled echo images on quantitative susceptibility and R2* mapping at 7T

Choi, S.; Li, X.; Harrison, D.

10.1101/529891 — bioengineering — Posted on 2019-01-24

875 Analysing linear multivariate pattern transformations in neuroimaging data

Basti, A.; Mur, M.; Kriegeskorte, N.; Pizzella, V.; Marzetti, L.; Hauk, O.

10.1101/497180 — neuroscience — Posted on 2019-01-24

876 A computational approach for characterizing the structural basis of intrinsic coupling modes of the cerebral cortex

Messe, A.; Meinert, L. J.; Hollensteiner, K. J.; Delettre, C.; Dell, L.-A.; Pieper, F.; Galindo-Leon, E. E.; Larrat, B.; Meriaux, S.; Mangin, J.-F.; Reillo, I.; de Juan Romero, C.; Borrell, V.; Toro, R.; Engler, G.; Engel, A. K.; Hilgetag, C. C.

10.1101/500009 — neuroscience — Posted on 2019-01-24

877 IsoSense: frequency enhanced sensorless adaptive optics through structured illumination

Zurauskas, M.; Dobbie, I. M.; Parton, R. M.; Phillips, M. A.; Gohler, A.; Davis, I.; Booth, M.

10.1101/448613 — bioengineering — Posted on 2019-01-24

878 SIMNETS: a computationally efficient and scalable framework for identifying sub-networks of functionally similar neurons

Hynes, J. B.; Brandman, D. M.; Zimmerman, J. B.; Donoghue, J. P.; Vargas-Irwin, C. E.

10.1101/463364 — neuroscience — Posted on 2019-01-24

879 Direct and transgenerational effects of an experimental heat wave on early life stages in a freshwater snail

Leicht, K.; Seppala, O.

10.1101/449777 — ecology — Posted on 2019-01-24

880 Harnessing natural diversity to identify key amino acid residues in prolidase

Schilbert, H. M.; Pellegrinelli, V.; Rodriguez-Cuenca, S.; Vidal-Puig, A.; Pucker, B.

10.1101/423475 — evolutionary biology — Posted on 2019-01-24

881 Genome-wide disruption of DNA methylation by 5-aza-2' deoxycytidine in the parasitoid wasp Nasonia vitripennis

Cook, N.; Parker, D. J.; Turner, F.; Tauber, E.; Pannebakker, B. A.; Shuker, D. M.

10.1101/437202 — evolutionary biology — Posted on 2019-01-24

882 Simultaneous multi-area recordings suggest a novel hypothesis about how attention improves performance

Ruff, D. A.; Cohen, M. R.

10.1101/372888 — neuroscience — Posted on 2019-01-24

883 Implicit temporal predictability biases slow oscillatory phase in auditory cortex and enhances pitch discrimination sensitivity

Herbst, S. K.; Obleser, J.

10.1101/410274 — neuroscience — Posted on 2019-01-24

884 Antibiotic inhibition of bacteria growth in droplets reveals heteroresistance pattern at the single cell level

Scheler, O.; Makuch, K.; Debski, P. R.; Horka, M.; Ruszczak, A.; Pacocha, N.; Sozanski, K.; Smolander, O.-P.; Postek, W.; Garstecki, P.

10.1101/328393 — microbiology — Posted on 2019-01-24

885 Mice adaptively generate choice variability in a deterministic task

Belkaid, M.; Bousseyrol, E.; Durand-de Cuttoli, R.; Dongelmans, M.; Durante, E. K.; Yahia, T. A.; Didienne, S.; Hannesse, B.; Come, M.; Mourot, A.; Naude, J.; Sigaud, O.; Faure, P.

10.1101/527580 — neuroscience — Posted on 2019-01-24

886 Electron microscopy reveals unique spore-like nano forms of Bacillus cereus

Ghosh, S.; Chakraborty, B.; Dey, S.; Biswas, C.; Chowdhury, R.; Chattopadhyay, K.; Sengupta, J.

10.1101/228833 — microbiology — Posted on 2019-01-24

887 TAF-ChIP: An ultra-low input approach for genome wide chromatin immunoprecipitation assay

Akhtar, J.; More, P.; Albrecht, S.; Marini, F.; Kulkarni, A.; Kaiser, W.; Wojnowski, L.; Fontaine, J.-F.; Andrade-Navarro, M. A.; Silies, M.; Berger, C.

10.1101/299727 — genomics — Posted on 2019-01-24

888 Comparative analysis of sfRNA in the genome of pre-epidemic and epidemic Zika viruses for host interacting proteins potentially related to the recent epidemic

Desingu, P. A.

10.1101/529370 — microbiology — Posted on 2019-01-24

889 The complete mitochondrial genome of the Golden Birdwing butterfly Troides aeacus: insights into phylogeny and divergence times of the superfamily Papilionoidea

Dong, S.-Y.; Jiang, G.-F.; Liu, G.; Hong, F.; Xu, Y.-F.

10.1101/529347 — evolutionary biology — Posted on 2019-01-24

890 C-terminal HSP90 Inhibitors Block the HSP90:HIF-1a Interaction and Inhibit the Cellular Hypoxic Response

Kataria, N.; Kerr, B.; Zaiter, S.; McAlpine, S. R.; Cook, K. M.

10.1101/521989 — cancer biology — Posted on 2019-01-24

891 Rapid Reconfiguration of the Functional Connectome after Chemogenetic Locus Coeruleus Activation

Zerbi, V.; Floriou-Servou, A.; Markicevic, M.; Vermeiren, Y.; Sturman, O.; Privitera, M.; von Ziegler, L.; Ferrari, K. D.; Weber, B.; De Deyn, P. P.; Wenderoth, N.; Bohacek, J.

10.1101/527457 — neuroscience — Posted on 2019-01-23

892 Posttraumatic Stress Disorder and the Social Brain: Affect-Related Disruption of the Default and Mirror Networks

Tan, K. M.; Burklund, L. J.; Craske, M. G.; Lieberman, M. D.

10.1101/527176 — neuroscience — Posted on 2019-01-23

893 Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson's Disease

Bryois, J.; Skene, N. G.; Folkmann Hansen, T.; Kogelman, L. J. A.; Watson, H. J.; Eating Disorders Working Group of the Psychiatric Genomics Consortium, ; International Headache Genetics Consortium, ; The 23andMe Research Team, ; Brueggeman, L.; Breen, G.; Bulik, C. M.; Arenas, E.; Hjerling-Leffler, J.; Sullivan, P. F.

10.1101/528463 — genomics — Posted on 2019-01-23

894 Tempo of gene regulation in wild and cultivated Vitis species shows coordination between cold deacclimation and budbreak

Pacheco Kovaleski, A.; Londo, J. P.

10.1101/528828 — plant biology — Posted on 2019-01-23

895 Sex differences in brain correlates of STEM anxiety

Gonzalez, A. A.; Bottenhorn, K. L.; Bartley, J. E.; Hayes, T.; Riedel, M. C.; Salo, T.; Bravo, E.; Odean, R.; Nazareth, A.; Laird, R. W.; Sutherland, M. T.; Brewe, E.; Pruden, S. M.; Laird, A. R.

10.1101/528075 — neuroscience — Posted on 2019-01-23

896 The symmetrical pattern of base-pair substitutions rates across the chromosome in Escherichia coli has multiple causes

Niccum, B. A.; Lee, H.; MohammedIsmail, W.; Tang, H.; Foster, P. L.

10.1101/523696 — microbiology — Posted on 2019-01-23

897 Inferring phenotypic plasticity and local adaptation to climate across tree species ranges using forest inventory data

Frejaville, T.; Fady, B.; Kremer, A.; Ducousso, A.; Benito Garzon, M.

10.1101/527390 — ecology — Posted on 2019-01-23

898 Parallel control of mechanosensory hair cell orientation by the PCP and Wnt pathways

Navajas Acedo, J.; Voas, M. G.; Alexander, R. L.; Woolley, T.; Unruh, J.; Li, H.; Moens, C.; Piotrowski, T.

10.1101/527937 — developmental biology — Posted on 2019-01-23

899 Cell-free gene regulatory network engineering with synthetic transcription factors

Swank, Z.; Laohakunakorn, N.; Maerkl, S. J.

10.1101/407999 — synthetic biology — Posted on 2019-01-23

900 Species Tree Inference under the Multispecies Coalescent on Data with Paralogs is Accurate

Du, P.; Hahn, M. W.; Nakhleh, L.

10.1101/498378 — evolutionary biology — Posted on 2019-01-23

901 Mapping of transgenic alleles in plants using a Nanopore-based sequencing strategy

Li, S.; Jia, S.; Hou, L.; Nguyen, H.; Sato, S.; Holding, D.; Cahoon, E.; Zhang, C.; Clemente, T.; Yu, B.

10.1101/529230 — plant biology — Posted on 2019-01-23

902 Imaging the spontaneous flow of thought: Distinct periods of cognition contribute to dynamic functional connectivity during rest

Gonzalez-Castillo, J.; Caballero-Gaudes, C.; Topolski, N.; Handwerker, D.; Pereira, F.; Bandettini, P.

10.1101/527804 — neuroscience — Posted on 2019-01-23

903 Phenotypic evolution is more constrained in simpler food webs

Barbour, M. A.; Greyson-Gaito, C. J.; Sootodeh, A.; Locke, B.; Bascompte, J.

10.1101/527416 — evolutionary biology — Posted on 2019-01-23

904 Mechanical feedback enables catch bonds to selectively stabilize scanning microvilli at T-cell surfaces

Pullen, R. H.; Abel, S. M.

10.1101/527903 — biophysics — Posted on 2019-01-23

905 Delayed start of first-time breeding and non-breeders surplus in the Western Siberian population of the European Pied Flycatcher

Grinkov, V. G.; Sternberg, H.

10.1101/387829 — zoology — Posted on 2019-01-23

906 New Asgard archaea capable of anaerobic hydrocarbon cycling

Seitz, K. W.; Dombrowski, N.; Eme, L.; Spang, A.; Lombard, J.; Sieber, J. R.; Teske, A. P.; Ettma, T. J. G.; Baker, B. J.

10.1101/527697 — microbiology — Posted on 2019-01-23

907 Expression kinetics and innate immune response after electroporation and lipid nanoparticle mediated delivery of a self-amplifying mRNA in the skin of mice

Huysmans, H.; Zhong, Z.; De Temmerman, J.; Mui, B. L.; Tam, Y. K.; Mc Cafferty, S.; Gitsels, A.; Vanrompay, D.; Sanders, N.

10.1101/528612 — immunology — Posted on 2019-01-23

908 A rapid method for DNA extraction of cotton mature fiber suitable for PCR fingerprinting

Ibrahim, S. D.; Alsamman, A. M.; Kahlifa, K.

10.1101/529305 — genomics — Posted on 2019-01-23

909 Character displacement within the breeding area questions reinforcement in Ficedula flycatchers

Grinkov, V. G.; Palko, I. V.; Sternberg, H.

10.1101/515916 — evolutionary biology — Posted on 2019-01-23

910 A Matched-filter Based Algorithm for Subcellular Classification of T-system in Cardiac Tissues

Colli, D. F.; Blood, R.; Sankarankutty, A. C.; Sachse, F. B.; Frisk, M.; Louch, W. E.; Kekenes-Huskey, P. M.

10.1101/371328 — biophysics — Posted on 2019-01-23

911 Comparison between diffusion MRI tractography and histological tract-tracing of cortico-cortical structural connectivity in the ferret brain

Delettre, C.; Messe, A.; Dell, L.-A.; Foubet, O.; Heuer, K.; Larrat, B.; Meriaux, S.; Mangin, J.-F.; Reillo, I.; de Juan Romero, C.; Borrell, V.; Toro, R.; Hilgetag, C. C.

10.1101/517136 — neuroscience — Posted on 2019-01-23

912 Characterization of Spontaneously Arising Chlorhexidine-Tolerant Variants in Streptococcus mutans

Kaspar, J. R.; Godwin, M. J.; Velsko, I. M.; Richards, V. P.; Burne, R. A.

10.1101/528471 — microbiology — Posted on 2019-01-23

913 Highly-accurate long-read sequencing improves variant detection and assembly of a human genome

Wenger, A. M.; Peluso, P.; Rowell, W. J.; Chang, P.-C.; Hall, R. J.; Concepcion, G. T.; Ebler, J.; Fungtammasan, A.; Kolesnikov, A.; Olson, N. D.; Toepfer, A.; Alonge, M.; Mahmoud, M.; Qian, Y.; Chin, C.-S.; Phillippy, A. M.; Schatz, M. C.; Myers, G.; DePristo, M. A.; Ruan, J.; Marschall, T.; Sedlazeck, F. J.; Zook, J. M.; Li, H.; Koren, S.; Carroll, A.; Rank, D. R.; Hunkapiller, M. W.

10.1101/519025 — genomics — Posted on 2019-01-23

914 Widespread selection for high and low secondary structure in coding sequences across all domains of life

Gebert, D.; Jehn, J.; Rosenkranz, D.

10.1101/524538 — evolutionary biology — Posted on 2019-01-23

915 The impact of isoniazid preventive therapy on tuberculosis among household contacts of isoniazid-resistant patients.

Huang, C.-C.; Becerra, M. C.; Calderon, R.; Contreras, C.; Galea, J.; Grandjean, L.; Lecca, L.; Yataco, R.; Zhang, Z.; Murray, M.

10.1101/479865 — epidemiology — Posted on 2019-01-23

916 Gastrocnemius fascicles are shorter and more pennate throughout the first month following acute Achilles tendon rupture

Hullfish, T. J.; O'Connor, K. M.; Baxter, J. R.

10.1101/445569 — bioengineering — Posted on 2019-01-23

917 Grouping effects in numerosity perception under prolonged viewing conditions

Poom, L.; Lindskog, M.; Winman, A.; van den Berg, R.

10.1101/460741 — animal behavior and cognition — Posted on 2019-01-23

918 Waterborne, abiotic and other indirectly transmitted (W.A.I.T.) infections are defined by the dynamics of free-living pathogens and environmental reservoirs

Miller-Dickson, M.; Meszaros, V. A.; Baffour-Awuah Junior, F.; Almagro-Moreno, S.; Ogbunugafor, C. B.

10.1101/525089 — systems biology — Posted on 2019-01-23

919 Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Preserves HDL Atheroprotective Functions

Huang, J.; Yancey, P. G.; Tao, H.; Borja, M.; Loren, S. E.; Kon, V.; Davies, S. S.; Linton, M. F.

10.1101/528026 — pharmacology and toxicology — Posted on 2019-01-23

920 Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals

Ulyanova, A. V.; Cottone, C.; Adam, C. D.; Gagnon, K. G.; Cullen, D. K.; Holtzman, T.; Jameison, B.; Koch, P. F.; Chen, H. I.; Johnson, V. E.; Wolf, J. A.

10.1101/400812 — neuroscience — Posted on 2019-01-23

921 Removal of behavioural and electrophysiological signs of chronic pain by in vivo microsections of rat somatosensory cortex with parallel X-ray microbeams

Zippo, A. G.; Bertoli, G. R.; Riccardi, M. P.; Valente, M.; Brauer-Krisch, E.; Caramenti, G. C.; Requardt, H.; Del Grosso, V.; Coan, P.; Bravin, A.; Biella, G. E. M.

10.1101/528539 — neuroscience — Posted on 2019-01-23

922 Investigating causal pathways between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.

Treur, J. L.; Demontis, D.; Smith, G. D.; Sallis, H.; ADHD working group of the Psychiatric Genomics Consortium, ; Richardson, T. G.; Wiers, R. W.; Borglum, A. D.; Verweij, K. J.; Munafo, M. R.

10.1101/524769 — genetics — Posted on 2019-01-23

923 The role of genetic diversity in the evolution and maintenance of environmentally-cued, male alternative reproductive tactics

Stewart, K.; Draaijer, R.; Kolasa, M.; Smallegange, I.

10.1101/528703 — evolutionary biology — Posted on 2019-01-23

924 Scale dependent patterns in interaction diversity maintain resiliency in a frequently disturbed ecosystem

Dell, J.; Salcido, D.; Lumpkin, W.; Richards, L.; Pokswinski, S.; Loudermilk, E. L.; O'Brien, J.; Dyer, L.

10.1101/528745 — ecology — Posted on 2019-01-23

925 Distinguishing the signatures of local environmental filtering and regional trait range limits in the study of trait-environment relationships

DENELLE, P.; Violle, C.; Munoz, F.

10.1101/528836 — ecology — Posted on 2019-01-23

926 MPRAnalyze - A statistical framework for Massively Parallel Reporter Assays

Ashuach, T.; Fischer, D. S.; Kreimer, A.; Ahituv, N.; Theis, F. J.; Yosef, N.

10.1101/527887 — bioinformatics — Posted on 2019-01-23

927 Proteome and Secretome Dynamics of Stem Cell-Derived Retinal Pigmented Epithelium in Response to Acute and Chronic ROS

Meyer, J. G.; Garcia, T. Y.; Schilling, B.; Gibson, B. W.; Lamba, D. A.

10.1101/529271 — systems biology — Posted on 2019-01-23

928 Metabolic landscape of the tumor microenvironment

Xiao, Z.; Dai, Z.; Locasale, J. W.

10.1101/527952 — systems biology — Posted on 2019-01-23

929 Multiple quantitative trait loci contribute tolerance to bacterial canker incited by Pseudomonas syringae pv. actinidiae in kiwifruit (Actinidia chinensis)

Tahir, J.; Gardiner, S. E.; Hoyte, S.; Bassett, H.; Brendolise, C.; Chatterjee, A.; Templeton, K.; Deng, C.; Crowhurst, R.; Montefiori, M.; Morgan, E.; Wotton, A.; Funnell, K.; Wiedow, C.; Knaebel, M.; Hedderley, D.; Vanneste, J.; McCallum, J.; Hoeata, K.; Chagne, D.; Gea, L.

10.1101/526798 — plant biology — Posted on 2019-01-23

930 Mitohormetic effects of rotenone drastically depend on age

Baumgart, M.; Ugolini, M.; Groth, M.; Platzer, M.; Cellerino, A.

10.1101/528547 — pharmacology and toxicology — Posted on 2019-01-23

931 Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats

Javadi-Paydar, M.; Kerr, T. M.; Harvey, E. L.; Cole, M.; Taffe, M. A.

10.1101/418699 — pharmacology and toxicology — Posted on 2019-01-23

932 Sulcal organization in the medial frontal cortex reveals insights into primate brain evolution

AMIEZ, C.; Sallet, J.; Hopkins, W. D.; Meguerditchian, A.; Hadj-Bouziane, F.; BenHamed, S.; Wilson, C. R. E.; Procyk, E.; Petrides, M.

10.1101/527374 — neuroscience — Posted on 2019-01-23

933 Environmental Consistency Modulation of Error Sensitivity During Motor Adaptation is Explicitly Controlled

Avraham, G.; Keizman, M.; Shmuelof, L.

10.1101/528752 — neuroscience — Posted on 2019-01-23

934 Neural pattern similarity differentially affects memory performance of younger and older adults

Sommer, V. R.; Fandakova, Y.; Grandy, T. H.; Shing, Y. L.; Werkle-Bergner, M.; Sander, M. C.

10.1101/528620 — neuroscience — Posted on 2019-01-23

935 Removal of Spo11 from meiotic DNA breaks in vitro but not in vivo by Tyrosyl DNA Phosphodiesterase 2

Neale, M.; Johnson, D.; Allison, R. M.; Cannavo, E.; Cejka, P.

10.1101/527333 — molecular biology — Posted on 2019-01-23

936 A novel thermostable aspartic protease from Talaromyces leycettanus and its specific autocatalytic activation through an intermediate transition state

Guo, Y.; Tu, T.; Ren, Y.; Wang, Y.; Bai, Y. G.; Su, X.; Wang, Y.; Yao, B.; Huang, H.; Luo, H.

10.1101/528265 — molecular biology — Posted on 2019-01-23

937 Mobile genetic element insertions drive antibiotic resistance across pathogens

Durrant, M.; Li, M. M.; Siranosian, B.; Bhatt, A. S.

10.1101/527788 — microbiology — Posted on 2019-01-23

938 DNA-foraging bacteria in the seafloor

Wasmund, K.; Pelikan, C.; Watzka, M.; Richter, A.; Noel, A. C.; Hubert, C. R. J.; Rattei, T.; Hofmann, T.; Herbold, C. W.; Loy, A.

10.1101/528695 — microbiology — Posted on 2019-01-23

939 Characterization of a thaumarchaeal symbiont that drives incomplete nitrification in the tropical sponge Ianthella basta

Moeller, F. U.; Webster, N. S.; Herbold, C. W.; Behnam, F.; Domman, D.; Albertsen, M.; Mooshammer, M.; Markert, S.; Turaev, D.; Becher, D.; Rattei, T.; Schweder, T.; Richter, A.; Watzka, M.; Nielsen, P. H.; Wagner, M.

10.1101/527234 — microbiology — Posted on 2019-01-23

940 A metabolic dependency for host isoprenoids in the obligate intracellular pathogen Rickettsia parkeri underlies a sensitivity for the statin class of host-targeted therapeutics

Ahyong, V.; Berdan, C. A.; Nomura, D. K.; Welch, M. D.

10.1101/528018 — microbiology — Posted on 2019-01-23

941 Microbial regulation of enteric eosinophils and its impact on tissue remodeling and Th2 immunity

Jimenez-Saiz, R.; Anipindi, V. C.; Galipeau, H.; Ellenbogen, Y.; Chaudhary, R.; Koenig, J. F.; Gordon, M. E.; Walker, T. D.; Mandur, T. S.; Abed, S.; Humbles, A.; Chu, D. K.; Ask, K.; Verdu, E. F.; Jordana, M.

10.1101/527473 — immunology — Posted on 2019-01-23

942 IL-5Rα marks nasal polyp IgG4 and IgE-secreting cells in aspirin-exacerbated respiratory disease

Buchheit, K. M.; Dwyer, D. F.; Ordovas-Montanes, J.; Katz, H. R.; Lewis, E.; Bhattacharyya, N.; Shalek, A. K.; Barrett, N. A.; Boyce, J. A.; Laidlaw, T. M.

10.1101/527762 — immunology — Posted on 2019-01-23

943 A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I

Toledo, M.; Sun, X.; Brieno-Enriquez, M. A.; Raghavan, V.; Gray, S.; Pea, J.; Venkatesh, A.; Patel, L.; Borst, P. L.; Alani, E.; Cohen, P. E.

10.1101/517748 — genetics — Posted on 2019-01-23

944 Identification of the best index case significantly improves mutation detection rates in families with hereditary breast and ovarian cancer

Wyrwoll, M.; Fuchs, L.; Waschk, D. E. J.

10.1101/527168 — genetics — Posted on 2019-01-23

945 Local adaptation under gene flow: Recombination, conditional neutrality and genetic trade-offs shape genomic patterns in Arabidopsis lyrata

Hämälä, T.; Savolainen, O.

10.1101/374900 — evolutionary biology — Posted on 2019-01-23

946 Vitamin D status and risk of incident tuberculosis disease: a systematic review and individual participant data meta-analysis

Aibana, O.; Huang, C.-C.; Aboud, S.; Arnedo-Pena, A.; Becerra, M. C.; Bellido-Blasco, J. B.; Bhosale, R.; Calderon, R.; Chiang, S.; Contreras, C.; Fawzi, W. W.; Franke, M. F.; Galea, J. T.; Garcia-Ferrer, D.; Gil-Fortuno, M.; Gomila-Sard, B.; Gupta, A.; Gupte, N.; Hussain, R.; Iborra-Millet, J.; Iqbal, N. T.; Juan-Cerdan, J. V.; Kinikar, A.; Lecca, L.; Mave, V.; Meseguer-Ferrer, N.; Montepiedra, G.; Mugusi, F. M.; Owolabi, O. A.; Parsonnet, J.; Roach-Poblete, F.; Romeu-Garcia, M. A.; Spector, S. A.; Sudfeld, C. R.; Tenforde, M. W.; Togun, T. O.; Yataco, R.; Zhang, Z.; Murray, M. B.

10.1101/481739 — epidemiology — Posted on 2019-01-23

947 Preformed Chromatin Topology Assists TranscriptionalRobustness of Shh during Limb Development

Paliou, C.; Guckelberger, P.; Schöpflin, R.; Heinrich, V.; Esposito, A.; Chiariello, A. M. M.; Bianco, S.; Annunziatella, C.; Helmuth, J.; Haas, S.; Jerkovic, I.; Brieske, N.; Wittler, L.; Timmermann, B.; Nicodemi, M.; Vingron, M.; Mundlos, S.; Andrey, G.

10.1101/528877 — developmental biology — Posted on 2019-01-23

948 The TRAPP complex mediates secretion arrest induced by stress granule assembly

Zappa, F.; Wilson, C.; Di Tullio, G.; Santoro, M.; Pucci, P.; Monti, M.; D'Amico, D.; Pisonero Vaquero, S.; De Cegli, R.; Romano, A.; Saleem, M.; Polishchuk, E.; Failli, M.; Giaquinto, L.; De Matteis, M. A.

10.1101/528380 — cell biology — Posted on 2019-01-23

949 A simple linearization method unveils hidden enzymatic assay interferences

Pinto, M. F.; Ripoll-Rozada, J.; Ramos, H.; Watson, E. E.; Franck, C.; Payne, R. J.; Saraiva, L.; Pereira, P. J. B.; Pastore, A.; Rocha, F.; Martins, P. M.

10.1101/528596 — biophysics — Posted on 2019-01-23

950 Empirical and Computational Comparison of Alternative Therapeutic Exon Skip Repairs for Duchenne Muscular Dystrophy

Ma, K. M.; Thomas, E. S.; Weresczczynski, J.; Menhart, N.

10.1101/527705 — biophysics — Posted on 2019-01-23

951 Cryo-EM structures reveal a conformational change of SOPA1 during mitochondrial inner membrane fusion

Zhang, D.; Zhang, Y.; Ma, J.; Niu, T.; Chen, W.; Pang, X.; Zhai, Y.; Sun, F.

10.1101/528042 — biophysics — Posted on 2019-01-23

952 Role of Disulfide Bonds and Topological Frustration in the Kinetic Partitioning of Lysozyme Folding Pathways

Muttathukattil, A. N.; Singh, P. C. N.; Reddy, G.

10.1101/528000 — biophysics — Posted on 2019-01-23

953 Comparative identification of microRNAs in Apis cerana cerana workers'midguts responding to Nosema ceranae invasion

Guo, R.; Chen, D.; Du, Y.; Chen, H.; Wang, H.; Xiong, C.; Zheng, Y.; Hou, C.; Diao, Q.

10.1101/528166 — bioinformatics — Posted on 2019-01-23

954 scAlign: a tool for alignment, integration and rare cell identification from scRNA-seq data

Johansen, N.; Quon, G.

10.1101/504944 — bioinformatics — Posted on 2019-01-23

955 Wikipedia network analysis of cancer interactions and world influence

Rollin, G.; Lages, J.; Shepelyansky, D.

10.1101/527879 — bioinformatics — Posted on 2019-01-23

956 Anhedonia following mild traumatic brain injury in rats: A behavioral economic analysis of positive and negative reinforcement

Avcu, P.; Fortress, A. M.; Fragale, J. E.; Spiegler, K.; Pang, K.

10.1101/527895 — animal behavior and cognition — Posted on 2019-01-23

957 Predicting correct serotypes using machine-learning models based on codon usage patterns of influenza A viruses

Yang, H.

10.1101/528083 — bioinformatics — Posted on 2019-01-23

958 Split Selectable Markers

Jillette, N.; Du, M.; Cheng, A. W.

10.1101/452979 — bioengineering — Posted on 2019-01-23

959 Postdoc X-ray in Europe 2017: work conditions, productivity, institutional support and career outlooks

Ribeiro, M. J.; Fonseca, A.; Moura-Ramos, M.; Costa, M.; Kilteni, K.; Andersen, L. M.; Harber-Aschan, L.; Moscoso, J. A.; Bagchi, S.; European Network of Postdoctoral Associations (ENPA),

10.1101/523621 — scientific communication and education — Posted on 2019-01-23

960 Intraoperative contrast-enhanced ultrasound for cerebral glioma resection and the relationship with microvessel density

Wang, J.; Liu, X.; Yang, Y.; Duan, Y.

10.1101/528281 — neuroscience — Posted on 2019-01-23

961 Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank

Warland, A.; Kendall, K.; Rees, E.; Kirov, G.; Caseras, X.

10.1101/374678 — neuroscience — Posted on 2019-01-23

962 Large-scale proteomic analysis of human prefrontal cortex identifies proteins associated with cognitive trajectory in advanced age

Wingo, A. P.; Dammer, E. B.; Breen, M. S.; Logsdon, B. A.; Duong, D. M.; Troncosco, J. C.; Thambisetty, M.; Beach, T. G.; Serrano, G. E.; Reiman, E. M.; Caselli, R. J.; Lah, J. J.; Seyfried, N. T.; Levey, A. I.; Wingo, T. S.

10.1101/526988 — neuroscience — Posted on 2019-01-23

963 Candida auris: multi-omics signature of an emerging and multidrug-resistant pathogen

Zamith-Miranda, D.; Heyman, H. M.; Cleare, L. G.; Couvillion, S. P.; Clair, G. C.; Bredeweg, E. L.; Gacser, A.; Nimrichter, L.; Nakayasu, E. S.; Nosanchuk, J. D.

10.1101/528232 — microbiology — Posted on 2019-01-23

964 UniProt Genomic Mapping for Deciphering Functional Effects of Missense Variants

McGarvey, P.; Nightingale, A.; Luo, J.; Huang, H.; Martin, M.-J.; Wu, C.; UniProt Consortium,

10.1101/192914 — genomics — Posted on 2019-01-23

965 Dosage-sensitivity of human transcription factor genes

Ni, Z.; Zhou, X.-Y.; Aslam, S.; Niu, D.-K.

10.1101/528554 — genetics — Posted on 2019-01-23

966 High-throughput phenotyping with deep learning gives insight into the genetic architecture of flowering time in wheat

Wang, X.; Xuan, H.; Evers, B.; Shrestha, S.; Pless, R.; Poland, J.

10.1101/527911 — genetics — Posted on 2019-01-23

967 Maternal age alters offspring lifespan, fitness, and lifespan extension under caloric restriction

Bock, M. J.; Jarvis, G. C.; Corey, E. L.; Stone, E. E.; Gribble, K. E.

10.1101/527770 — evolutionary biology — Posted on 2019-01-23

968 Continent-wide structure of bacterial microbiomes of European Drosophila melanogaster suggests host-control

Wang, Y.; Kapun, M.; Waidele, L.; Kuenzel, S.; Bergland, A.; Staubach, F.

10.1101/527531 — evolutionary biology — Posted on 2019-01-23

969 Worldwide impacts of human on animal genetic diversity

Millette, K. L.; Fugere, V.; Debyser, C.; Greiner, A.; Chain, F. J. J.; Gonzalez, A.

10.1101/527739 — evolutionary biology — Posted on 2019-01-23

970 A bird's white-eye view on avian sex chromosome evolution

Leroy, T.; Anselmetti, Y.; Tilak, M.-K.; Berard, S.; Csukonyi, L.; Gabrielli, M.; Scornavacca, C.; Mila, B.; Thebaud, C.; Nabholz, B.

10.1101/505610 — evolutionary biology — Posted on 2019-01-23

971 Individuals' expected genetic contributions to future generations, reproductive value, and short-term metrics of fitness in free-living song sparrows (Melospiza melodia)

Reid, J.; Nietlisbach, P.; Wolak, M.; Keller, L.; Arcese, P.

10.1101/528513 — evolutionary biology — Posted on 2019-01-23

972 A pair of E3 ubiquitin ligases compete to regulate axon guidance and filopodial dynamics

Boyer, N. P.; McCormick, L. E.; Urbina, F. L.; Gupton, S.

10.1101/529222 — cell biology — Posted on 2019-01-23

973 Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry

Sogin, E. M.; Puskas, E.; Dubilier, N.; Liebeke, M.

10.1101/528307 — biochemistry — Posted on 2019-01-23

974 The visual system of the genetically tractable crustacean Parhyale hawaiensis: diversification of eyes and visual circuits associated with low-resolution vision

Ramos, A. P.; Gustafsson, O.; Labert, N.; Salecker, I.; Nilsson, D. E.; Averof, M.

10.1101/527564 — zoology — Posted on 2019-01-23

975 Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell lines

Buiga, P.; Elson, A.; Tabernero, L.; Schwartz, J.-M.

10.1101/528315 — systems biology — Posted on 2019-01-23

976 MaXLinker: proteome-wide cross-link identifications with high specificity and sensitivity

Yugandhar, K.; Wang, T.-Y.; Leung, A. K.-Y.; Lanz, M. C.; Motorykin, I.; Liang, J.; Shayhidin, E. E.; Smolka, M. B.; Zhang, S.; Yu, H.

10.1101/526897 — systems biology — Posted on 2019-01-23

977 Partitioning stable and unstable expression level variation in cell populations: a theoretical framework with application to the T cell receptor

Guzella, T. S.; Barreto, V. M.; Carneiro, J.

10.1101/527663 — systems biology — Posted on 2019-01-23

978 Members of the Arabidopsis auxin receptor gene family are essential early in embryogenesis and have broadly overlapping functions

Prigge, M. J.; Kadakia, N.; Greenham, K.; Estelle, M.

10.1101/529248 — plant biology — Posted on 2019-01-23

979 What do I do now? Intolerance of uncertainty is associated with discrete patterns of anticipatory physiological responding to different uncertain contexts

Morriss, J.

10.1101/527317 — neuroscience — Posted on 2019-01-23

980 Quantification and Isolation of Bacillus subtilis Spores using Cell Sorting and automated Gating.

Karava, M.; Bracharz, F.; Kabisch, J.

10.1101/528257 — microbiology — Posted on 2019-01-23

981 Honey bee trypanosomatid parasite dynamically changes the transcriptome during the infection of honey bee and modifies the host physiology

Liu, Q.; Lei, J.; Darby, A. C.; Kadowaki, T.

10.1101/529321 — microbiology — Posted on 2019-01-23

982 15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

Evans, R. J.; Pline, K.; Loynes, C.; Needs, S.; Aldrovandi, M.; Tifenbach, J.; Bielska, E.; Rubino, R.; Nicol, C.; May, R. C.; Krause, H.; O'Donnell, V.; Renshaw, S.; Johnston, S.

10.1101/113167 — microbiology — Posted on 2019-01-23

983 Conduit integrity is compromised during acute lymph node expansion

Martinez, V. G.; Pankova, V.; Krasny, L.; Singh, T.; White, I.; Benjamin, A.; Dertschnig, S.; Horsnell, H.; Kristin-Vizi, J.; Burden, J.; Huang, P.; Tape, C.; Acton, S. E.

10.1101/527481 — immunology — Posted on 2019-01-23

984 A cellular census of healthy lung and asthmatic airway wall identifies novel cell states in health and disease

Vieira Braga, F. A.; Kar, G.; Berg, M.; Carpaij, O. A.; Polanski, K.; Simon, L. M.; Brouwer, S.; Gomes, T.; Hesse, L.; Jiang, J.; Fasouli, E. S.; Efremova, M.; Vento-Tormo, R.; Affleck, K.; Palit, S.; Strzelecka, P.; Firth, H. V.; Mahbubani, K. T.; Cvejic, A.; Meyer, K. B.; Saeb-Parsy, K.; Luinge, M.; Brandsma, C.-A.; Timens, W.; Angelidis, I.; Strunz, M.; Koppelman, G. H.; van Oosterhout, A. J.; Schiller, H. B.; Theis, F. J.; van den Berge, M.; Nawijn, M. C.; Teichmann, S. A.

10.1101/527408 — immunology — Posted on 2019-01-23

985 Leveraging tissue specific gene expression regulation to identify genes associated with complex diseases

Liu, W.; Li, M.; Zhang, W.; Zhou, G.; Wu, X.; Wang, J.; Zhao, H.

10.1101/529297 — genetics — Posted on 2019-01-23

986 Mutational Landscape of Spontaneous Base Substitutions and Small Indels in Experimental Caenorhabditis elegans Populations of Differing Size

Konrad, A.; Brady, M. J.; Bergthorsson, U.; Katju, V.

10.1101/529214 — evolutionary biology — Posted on 2019-01-23

987 Estimating seed dispersal distance: a comparison of methods using animal movement and plant genetic data on two primate-dispersed Neotropical plant species

Gelmi-Candusso, T. A.; Bialozyt, R.; Slana, D.; Zarate-Gomez, R.; Heymann, E. W.; Heer, K.

10.1101/528448 — ecology — Posted on 2019-01-23

988 C/EBPδ demonstrates dichotomous tumor initiation and promotion in high grade serous ovarian carcinogenesis

Sowamber, R.; Chehade, R.; Bitar, M.; Dodds, L.; Milea, A.; Shaw, P.; George, S. H.

10.1101/528885 — cancer biology — Posted on 2019-01-23

989 The Evolution of Placental Invasion and Cancer Metastasis are Causally Linked

Gupta, K.; Afzal, J.; Maziarz, J. D.; Hamidzadeh, A.; Liang, C.; Erkenbrack, E. M.; Nam, H.; Haeger, J.-D.; Pfarrer, C.; Hoang, T.; Ott, T.; Spencer, T.; Pavlicev, M.; Antczak, D.; Levchenko, A.; Wagner, G. P.

10.1101/528646 — cancer biology — Posted on 2019-01-23

990 RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma

Naert, T.; Dimitrakopoulou, D.; Tulkens, D.; Demuynck, S.; Noelanders, R.; Eeckhout, L.; Van Isterdael, G.; Deforce, D.; Vanhove, C.; Van Dorpe, J.; Creytens, D.; Vleminckx, K.

10.1101/528299 — cancer biology — Posted on 2019-01-23

991 DisCVR: Rapid viral diagnosis from high-throughput sequencing data

Maabar, M.; Davison, A. J.; Palmarini, M.; Hughes, J.

10.1101/527127 — bioinformatics — Posted on 2019-01-23

992 NORTH: a highly accurate and scalable Naive Bayes based ORTHologous gene clustering algorithm

Ibtehaz, N.; Ahmed, S.; Saha, B.; Rahman, M. S.; Bayzid, M. S.

10.1101/528323 — bioinformatics — Posted on 2019-01-23

993 The number of spaced-word matches between two DNA sequences as a function of the underlying pattern weight

Röhling, S.; Morgenstern, B.

10.1101/527515 — bioinformatics — Posted on 2019-01-23

994 Verticillium dahliae strains that infect the same host plant display highly divergent effector catalogs

Gibriel, H.; Li, J.; Zhu, L.; Seidl, M.; Thomma, B.

10.1101/528729 — plant biology — Posted on 2019-01-23

995 Mitigative effects of Alpha-lipoic acid for the toxicity of Dimethoate in male rats

Abdelsalam, H.

10.1101/527283 — physiology — Posted on 2019-01-23

996 Cortical and subcortical neurons discriminate sounds in noise on the sole basis of acoustic amplitude modulations

Souffi, S.; Lorenzi, C.; Huetz, C.; Edeline, J.-M.

10.1101/528653 — neuroscience — Posted on 2019-01-23

997 Ketamine Affects Prediction Errors About Statistical Regularities: A Computational Single-Trial Analysis of the Mismatch Negativity

Weber, L.; Diaconescu, A. O.; Mathys, C.; Schmidt, A.; Kometer, M.; Vollenweider, F.; Stephan, K. E.

10.1101/528372 — neuroscience — Posted on 2019-01-23

998 Subcortical Anatomy of the Default Mode Network: a functional and structural connectivity study

Alves, P. N.; Foulon, C.; Karolis, V.; Bzdok, D.; Margulies, D. S.; Volle, E.; Thiebaut de Schotten, M.

10.1101/528679 — neuroscience — Posted on 2019-01-23

999 A robust human norovirus replication model in zebrafish larvae

Van Dycke, J.; Ny, A.; Conceicao-Neto, N.; Maes, J.; Hosmillo, M.; Cuvry, A.; Goodfellow, I.; de Araujo Nogueira, T. C.; Verbeken, E.; Matthijnssens, J.; de Witte, P.; Neyts, J.; Rocha-Pereira, J.

10.1101/528364 — microbiology — Posted on 2019-01-23

1000 An integrated metagenome catalog reveals novel insights into the murine gut microbiome

Lesker, T. R.; Chakravarthy, A.; Galvez, E. J. C.; Lagkouvardos, I.; Baines, J. F.; Clavel, T.; Sczyrba, A.; McHardy, A.; Strowig, T.

10.1101/528737 — microbiology — Posted on 2019-01-23

1001 Investigating Genetic Heterogeneity in Major Depression Through Item-level Genetic Analyses of the PHQ-9

Thorp, J. G.; Marees, A.; Ong, J.-S.; An, J.; MacGregor, S.; Derks, E.

10.1101/528067 — genetics — Posted on 2019-01-23

1002 Adaptation and the Parliament of Genes

Scott, T. W.; West, S. A.

10.1101/526970 — evolutionary biology — Posted on 2019-01-23

1003 Habitat loss does not always entail negative genetic consequences

Carvalho, C. d. S.; Lanes, E. C.; Silva, A. R.; Caldeira, C. F.; Carvalho-Filho, N.; Gastauer, M.; Imperatriz-Fonseca, V. L.; Nascimento, W.; Oliveira, G.; Siqueira, J. O.; Viana, P. L.; Jaffe, R.

10.1101/528430 — ecology — Posted on 2019-01-23

1004 AirSurf-Lettuce: an aerial image analysis platform for ultra-scale field phenotyping and precision agriculture using computer vision and deep learning

Bauer, A.; Bostrom, A.; Ball, J.; Applegate, C.; Cheng, T.; Laycock, S.; Moreno Rojas, S.; Kirwan, J.; Zhou, J.

10.1101/527184 — bioinformatics — Posted on 2019-01-23

1005 Computational Analysis Revealed Five Novel Mutations in Human IL2RG gene Related to X-SCID

Abbas, T. B.; Ali Hassan, A. A.; Abdelgadir, A. E.; Mohammed, W. O.; Abdelhameed, T. A.; Hassan, M. A.

10.1101/528349 — bioinformatics — Posted on 2019-01-23

1006 High-affinity free ubiquitin sensors as quantitative probes of ubiquitin homeostasis and deubiquitination

Choi, Y.-S.; Bollinger, S. A.; Prada, L. F.; Scavone, F.; Yao, T.; Cohen, R. E.

10.1101/528711 — biochemistry — Posted on 2019-01-23

1007 Can grid cell ensembles represent multiple spaces?

Spalla, D.; Dubreuil, A.; Rosay, S.; Monasson, R.; Treves, A.

10.1101/527192 — neuroscience — Posted on 2019-01-23

1008 Tanycyte-independent control of hypothalamic leptin signaling

Yoo, S.; Cha, D.; Kim, D. W.; Hoang, T.; Blackshaw, S.

10.1101/528794 — neuroscience — Posted on 2019-01-23

1009 An MRI Atrophy Biomarker Predicts Global Prognosis in Early De Novo Parkinson's Disease

Zeighami, Y.; Fereshtehnejad, S.-M.; Dadar, M.; Collins, D. L.; Postuma, R. B.; Dagher, A.

10.1101/528810 — neuroscience — Posted on 2019-01-23

1010 CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis

Zhu, Q.; Liu, N.; Orkin, S. H.; Yuan, G.-c.

10.1101/529081 — genomics — Posted on 2019-01-23

1011 Intra-familial phenotypic heterogeneity and telomere abnormality in von Hippel-Lindau disease

Wang, J.; Peng, X.; Chen, C.; Ning, X.; Peng, S.; Li, T.; Liu, S.; Hong, B.; Zhou, J.; Ma, K.; Cai, L.; Gong, K.

10.1101/526913 — genetics — Posted on 2019-01-23

1012 Parasite dispersal influences introgression rate

Doña, J.; Sweet, A.; Johnson, K.

10.1101/527226 — evolutionary biology — Posted on 2019-01-23

1013 Piezo1 is required for outflow tract and aortic valve development.

Faucherre, A.; Moha ou Maati, H.; Nasr, N.; Pinard, A.; Theron, A.; Odelin, G.; Desvignes, J. P.; Salgado, D.; Collod Beroud, G.; Avierinos, J. F.; Lebon, G.; Zaffran, S.; Jopling, C.

10.1101/528588 — developmental biology — Posted on 2019-01-23

1014 CHAP: a versatile tool for the structural and functional annotation of ion channel pores

Klesse, G.; Rao, S.; Sansom, M. S.; Tucker, S. J.

10.1101/527275 — biophysics — Posted on 2019-01-23

1015 Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Alves Faria Diniz, C. R.; Biojone, C.; Joca, S.; Rantamaki, T.; Castren, E.; Guimaraes, F.; Casarotto, P.

10.1101/427153 — neuroscience — Posted on 2019-01-23

1016 The association of plasma lipids with white blood cell counts: Results from the Multi-Ethnic Study of Atherosclerosis

Lai, Y. C.; Woollard, K.; McClelland, R.; Allison, M.; Rye, K.-A.; Ong, K. L.; Cochran, B. J.

10.1101/488023 — epidemiology — Posted on 2019-01-23

1017 Temporal inhibition of autophagy reveals segmental reversal of aging with increased cancer risk

Cassidy, L.; Young, A. R.; Young, C. N.; Soilleux, E. J.; Fielder, E.; Weigand, B. M.; Brais, R.; Wiggins, K. A.; Clarke, M. C.; Jurk, D.; Passos, J. F.; Narita, M.

10.1101/528984 — cancer biology — Posted on 2019-01-23

1018 A High-Throughput Screen of a Library of Therapeutics Identifies Substrates of P-glycoprotein

Lee, T. D.; Lee, O. W.; Brimacombe, K. R.; Chen, L.; Guha, R.; Lusvarghi, S.; Tebase, B. G.; Klumpp-Thomas, C.; Robey, R. W.; Ambudkar, S. V.; Shen, M.; Gottesman, M. M.; Hall, M. D.

10.1101/528992 — pharmacology and toxicology — Posted on 2019-01-23

1019 A multi-scale model reveals cellular and physiological mechanisms underlying hyperpolarisation-gated synaptic plasticity

Xie, Y.; Kazmierczyk, M.; Graham, B. P.; Dutia, M. B.; Stefan, M. I.

10.1101/418228 — neuroscience — Posted on 2019-01-23

1020 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer disease and three causality networks of AD: the GR@ACE project.

Moreno-Grau, S.; de Rojas, I.; Hernandez, I.; Quintela, I.; Montrreal, L.; Alegret, M.; Olasagarre, B.; Madrid, L.; Gonzalez, A.; Marona, O.; Rosende-Roca, M.; Mauleon, A.; Vargas, L.; Lafuente, A.; Abdelnour, C.; Rodriguez-Gonzalez, O.; Gil, S.; Santos-Santos, M. A.; Espinosa, A.; Ortega, G.; Sanabria, A.; Perez-Cordon, A.; Ruiz, S.; Aguilera, N.; Pineda, J. A.; Macias, J.; Alarcon-Martin, E.; Sotolongo-Grau, O.; GR@ACE consortium, ; DEGESCO consortium, ; Alzheimer Disease Neuroimaging Initiative, ; Marquie, M.; Monte-Rubio, G.; Valero, S.; Clarimon, J.; Bullido, M. J.; Garcia-Ribas, G.; P

10.1101/528901 — neuroscience — Posted on 2019-01-23

1021 A Silk-Expressed Pectin Methylesterase Confers Cross-Incompatibility Between Wild and Domesticated Strains of Zea mays

Lu, Y.; Hokin, S. A.; Kermicle, J. L.; Evans, M. M. S.

10.1101/529032 — evolutionary biology — Posted on 2019-01-23

1022 Selective enrichment of A-to-I edited transcripts from cellular RNA using Endonuclease V

Knutson, S. D.; Heemstra, J. M.

10.1101/522029 — molecular biology — Posted on 2019-01-23

1023 Microbial phenotypic heterogeneity in response to a metabolic toxin: continuous, dynamically shifting distribution of formaldehyde tolerance in Methylobacterium extorquens populations

Lee, J. A.; Riazi, S.; Nemati, S. H.; Vasdekis, A. E.; Ridenhour, B. J.; Remien, C. H.; Marx, C. J.

10.1101/529156 — microbiology — Posted on 2019-01-23

1024 Incomplete influenza A virus genomes are abundant but readily complemented during spatially structured viral spread

Jacobs, N. T.; Onuoha, N. O.; Antia, A.; Antia, R.; Steel, J.; Lowen, A. C.

10.1101/529065 — microbiology — Posted on 2019-01-23

1025 Hybrid optical gating for long-term 3D time-lapse imaging of the beating embryonic zebrafish heart

Taylor, J. M.; Nelson, C. J.; Bruton, F. A.; Baghbadrani, A. K.; Buckley, C.; Tucker, C. S.; Mullins, J. J.; Denvir, M. A.

10.1101/526830 — bioinformatics — Posted on 2019-01-23

1026 Deletion of Lats 1 and 2 in mouse pancreatic acinar cells induces pancreatic fibrosis and inflammation

Gao, M.; Liu, J.; Nipper, M.; Sharkey, F. E.; Johnson, R. L.; Crawford, H. C.; Chen, Y. D.; Wang, P.

10.1101/522938 — molecular biology — Posted on 2019-01-23

1027 Identification of sample mix-ups and mixtures in microbiome data in Diversity Outbred mice

Lobo, A. K.; Traeger, L. L.; Keller, M. P.; Attie, A. D.; Rey, F. E.; Broman, K. W.

10.1101/529040 — genetics — Posted on 2019-01-23

1028 Behavior influences range limits and patterns of coexistence across an elevational gradient in tropical bird diversity

Freeman, B. G.; Tobias, J.; Schluter, D.

10.1101/528950 — ecology — Posted on 2019-01-23

1029 Temporal changes in species composition affect a ubiquitous species views of patch quality

Bledsoe, E. K.; Ernest, S. M.

10.1101/528935 — ecology — Posted on 2019-01-23

1030 A flow extension tethered particle motion assay for single-molecule proteolysis

Drabek, A. A.; Loparo, J. J.; Blacklow, S. C.

10.1101/528919 — biophysics — Posted on 2019-01-23

1031 Semi-blind sparse affine spectral unmixing of autofluorescence-contaminated micrographs

Rossetti, B. J.; Wilbert, S. A.; Mark Welch, J. L.; Borisy, G. G.; Nagy, J. G.

10.1101/529008 — bioinformatics — Posted on 2019-01-23

1032 Social hierarchy position in female mice is associated with plasma corticosterone levels and hypothalamic gene expression

Williamson, C. M.; Lee, W.; Decasien, A. R.; Lanham, A.; Romeo, R. D.; Curley, J. P.

10.1101/529131 — animal behavior and cognition — Posted on 2019-01-23

1033 Dynamic control of pathway expression with riboregulated switchable feedback promoters

Glasscock, C. J.; Lazar, J. T.; Biggs, B. W.; Arnold, J. H.; Kang, M.-K.; Tullman-Ercek, D.; Tyo, K. E. J.; Lucks, J. B.

10.1101/529180 — synthetic biology — Posted on 2019-01-23

1034 White matter regions with low microstructure in young adults are associated with white matter hyperintensities in late life

Lao, P.; Vorberger, R.; Narkhede, A.; Gazes, Y.; Igwe, K.; Guzman, V.; Last, B.; Habeck, C.; Stern, Y.; Brickman, A.

10.1101/517763 — neuroscience — Posted on 2019-01-23

1035 Mechanically activated Piezo channels control outflow tract valve development through Yap1 and Klf2-Notch signaling axis

Duchemin, A. L.; Vignes, H.; Vermot, J.

10.1101/529016 — developmental biology — Posted on 2019-01-23

1036 Microbial networks in SPRING - Semi-parametric rank-based correlation and partial correlation estimation for quantitative microbiome data

Yoon, G.; Gaynanova, I.; Müller, C. L.

10.1101/526871 — bioinformatics — Posted on 2019-01-23

1037 Mai1 protein acts between host recognition of pathogen effectors and MAPK signaling

Hind, S. R.; Roberts, R.; Pedley, K. F.; Diner, B. A.; Szarzanowicz, M. J.; Luciano-Rosario, D.; Majhi, B. B.; Popov, G.; Sessa, G.; Oh, C.-S.; Martin, G. B.

10.1101/529172 — plant biology — Posted on 2019-01-23

1038 Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

Dubois, V.; Pawlik, A.; Bories, A.; Le Moigne, V.; Sismeiro, O.; Legendre, R.; Varet, H.; Rodriguez, P.; Gaillard, J.-L.; Copee, J.-Y.; Brosch, R.; Herrmann, J.-L.; Girard-misguich, F.

10.1101/529057 — microbiology — Posted on 2019-01-23

1039 IL-10-producing B cells are enriched in murine pericardial adipose tissues and ameliorate the outcome of acute myocardial infarction

Van Kaer, L.; Wu, L.; Dalal, R.; Cao, C.; Postoack, J. L.; Zhang, Q.; Wang, Z.; Lal, H.

10.1101/520742 — immunology — Posted on 2019-01-23

1040 Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

Hou, K.; Burch, K. S.; Majumdar, A.; Shi, H.; Mancuso, N.; Wu, Y.; Sankararaman, S.; Pasaniuc, B.

10.1101/526855 — genomics — Posted on 2019-01-23

1041 Cytokinetic furrowing and abscission dynamics during brain development revealed by live imaging

McNeely, K. C.; Little, J. N.; Dwyer, N.

10.1101/529164 — developmental biology — Posted on 2019-01-23

1042 Sex Differences in Mutational Processes

10.1101/528968 — cancer biology — Posted on 2019-01-23

1043 Cortico-hippocampal network connections support the multidimensional quality of episodic memory

Cooper, R. A.; Ritchey, M.

10.1101/526657 — neuroscience — Posted on 2019-01-23

1044 Cell type composition and circuit organization of neocortical radial clones

Cadwell, C. R.; Scala, F.; Fahey, P. G.; Kobak, D.; Sinz, F. H.; Johnsson, P.; Li, S.; Cotton, R. J.; Sandberg, R.; Berens, P.; Jiang, X.; Tolias, A. S.

10.1101/526681 — neuroscience — Posted on 2019-01-23

1045 A Novel Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Sixteen Disease and Physiological States

Altman, M. C.; Rinchai, D.; Baldwin, N.; Whalen, E.; Garand, M.; Kabeer, B. A.; Toufiq, M.; Presnell, S.; Chiche, L.; Jourde-Chiche, N.; Phillips, T.; Klintmalm, G.; O'Garra, A.; Berry, M.; Bloom, C.; Wilkinson, R. J.; Graham, C. M.; Lipman, M.; Lertmemongkolchai, G.; Bedognetti, D.; Kheradmand, F.; Mejias, A.; Ramilo, O.; Palucka, K.; Pascual, V.; Banchereau, J.; Chaussabel, D.

10.1101/525709 — immunology — Posted on 2019-01-23

1046 Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity

Thakkar, N.; Bailey-Kellogg, C.

10.1101/526467 — bioinformatics — Posted on 2019-01-23

1047 Brain Abnormalities Associated with Self-Injurious Thoughts and Behaviors: A Meta-Analysis of Neuroimaging Studies

Huang, X.; Rootes-Murdy, K.; Bastidas, D. M.; Nee, D. E.; Franklin, J. C.

10.1101/526525 — neuroscience — Posted on 2019-01-23

1048 Adapting genotyping-by-sequencing and variant calling for heterogeneous stock rats

Gao, J.; Gileta, A. F.; Bimschleger, H. V.; St. Pierre, C. L.; Gopalakrishnan, S.; Palmer, A. A.

10.1101/523043 — genetics — Posted on 2019-01-23

1049 Induction of the HIF pathway: Differential regulation by chemical hypoxia and oxygen glucose deprivation

Novak, A. E.; Jones, S. M.; Elliott, J. P.

10.1101/525006 — neuroscience — Posted on 2019-01-23

1050 Brain activity links performance in science reasoning with conceptual approach

Bartley, J. E.; Riedel, M. C.; Salo, T.; Boeving, E. R.; Bottenhorn, K. L.; Bravo, E. I.; Odean, R.; Nazareth, A.; Laird, R. W.; Sutherland, M. T.; Pruden, S. M.; Brewe, E.; Laird, A. R.

10.1101/526574 — neuroscience — Posted on 2019-01-23

1051 Trophic complexity alters the diversity-multifunctionality relationship in experimental grassland mesocosms

Anujan, K.; Heilpern, S. A.; Prager, C. M.; Naeem, S.

10.1101/525881 — ecology — Posted on 2019-01-23

1052 Synchronization of sensory gamma oscillations promotes multisensory communication

Misselhorn, J.; Schwab, B. C.; Schneider, T. R.; Engel, A. K.

10.1101/523688 — neuroscience — Posted on 2019-01-23

1053 Absolute and relative pitch processing in the human brain: Neural and behavioral evidence

Leipold, S.; Brauchli, C.; Greber, M.; Jaencke, L.

10.1101/526541 — neuroscience — Posted on 2019-01-23

1054 Relevance of the iron-responsive element (IRE) pseudotriloop structure for IRP1/2 binding and validation of IRE-like structures using the yeast three-hybrid system

Chen, S.-C.; Olsthoorn, R. C. L.

10.1101/524991 — molecular biology — Posted on 2019-01-23

1055 Interspecies metabolite transfer in a co-culture of Dehalococcoides and Sulfurospirillum leads to rapid and complete tetrachloroethene dechlorination

Kruse, S.; Tuerkowsky, D.; Birkigt, J.; Matturro, B.; Franke, S.; Jehmlich, N.; von Bergen, M.; Westermann, M.; Rossetti, S.; Nijenhuis, I.; Adrian, L.; Diekert, G.; Goris, T.

10.1101/526210 — microbiology — Posted on 2019-01-23

1056 Human discrimination and categorization of emotions in voices: a functional Near-Infrared Spectroscopy (fNIRS) study

Gruber, T.; Debracque, C.; Ceravolo, L.; Igloi, K.; Marin Bosch, B.; Fruehholz, S.; Grandjean, D.

10.1101/526558 — neuroscience — Posted on 2019-01-23

1057 Multi-trait meta-analyses reveal 25 quantitative trait loci for economically important traits in Brown Swiss cattle

Fang, Z.-H.; Pausch, H.

10.1101/517276 — genomics — Posted on 2019-01-23

1058 SHORT COMMUNICATION: Validation of a novel milk progesterone based tool to monitor luteolysis in dairy cows. Performance on cost-effective, on-farm measured data

Adriaens, I.; Saeys, W.; Geerinckx, K.; De Ketelaere, B.; Aernouts, B.

10.1101/526061 — bioengineering — Posted on 2019-01-23

1059 Incorporating prior information into signal-detection analyses across biologically informed gene-sets

Zhang, M.; Gelfman, S.; McCarthy, J.; Goldstein, D. B.; Allen, A. S.

10.1101/525840 — genetics — Posted on 2019-01-23

1060 Cis-epistasis at the LPA locus and risk of coronary artery disease

Zeng, L.; Mirza-Schreiber, N.; Lamina, C.; Coassin, S.; Nelson, C. P.; Franzen, O.; Kleber, M. E.; Friedel, S.; Andlauer, T. F. M.; Jiang, B.; Stiller, B.; Li, L.; Willenborg, C.; Munz, M.; Kessler, T.; Kastrati, A.; Laugwitz, K.-L.; Erdmann, J.; Moebus, S.; Noethen, M. M.; Peters, A.; Strauch, K.; Mueller-Nurasyid, M.; Gieger, C.; Meitinger, T.; Steinhagen-Thiessen, E.; Maerz, W.; Bjorkegren, J. L. M.; Samani, N. J.; Kronenberg, F.; Mueller-Myhsok, B.; Schunkert, H.

10.1101/518290 — genetics — Posted on 2019-01-23

1061 Life history parameters in acellular extrinsic fiber cementum microstructure

Edinborough, M.; Fearn, S.; Pilgrim, M.; Cvetkovic, A.; Mihailovic, B.; Grbic, R.; Edinborough, K.

10.1101/528760 — developmental biology — Posted on 2019-01-23

1062 Cryopreservation of Paramecium bursaria Chlorella Virus-1 during an active infection cycle of its host

Coy, S. R.; Alsante, A. N.; Van Etten, J. L.; Wilhelm, S. W.

10.1101/528786 — microbiology — Posted on 2019-01-23

1063 DNA aptamers for the recognition of HMGB1 from Plasmodium falciparum

Joseph, D. F.; Nakamoto, J. A.; Garcia Ruiz, O. A.; Penaranda, K.; Sanchez-Castro, A. E.; Castillo, P. S.; Milon, P.

10.1101/528778 — bioengineering — Posted on 2019-01-23

1064 Multiple quantitative trait loci contribute tolerance to bacterial canker incited by Pseudomonas syringae pv. actinidiae in kiwifruit (Actinidia chinensis)

Tahir, J.; Gardiner, S.; Hoyte, S.; Bassett, H.; Brendolise, C.; Chatterjee, A.; Templeton, K.; Deng, C.; Crowhurst, R.; Montefiori, M.; Morgan, E.; Wotton, A.; Funnell, K.; Wiedow, C.; Knaebel, M.; Hedderley, D.; Vanneste, J.; McCallum, J.; Hoeata, K.; Chagne, D.; Gea, L.

10.1101/526798 — plant biology — Posted on 2019-01-23

1065 A cis-carotene derived apocarotenoid regulates etioplast and chloroplast development

Cazzonelli, C. I.; Hou, X.; Alagoz, Y.; Rivers, J.; Dhami, N.; Lee, J.; Marri, S.; Pogson, B. J.

10.1101/528331 — plant biology — Posted on 2019-01-23

1066 Phosphorylation-dependent routing of RLP44 towards brassinosteroid or phytosulfokine signalling

Garnelo Gomez, B.; Lozano-Duran, R.; Wolf, S.

10.1101/527754 — plant biology — Posted on 2019-01-23

1067 N6-methyladenosine dynamics during early vertebrate embryogenesis

Aanes, H.; Engelsen, D.; Manaf, A.; Alemu, E. A.; Vagbo, C. B.; Martin, L.; Lerdrup, M.; Hansen, K.; Mathavan, S.; Winata, C.; Darnell, R. B.; Alestrom, P.; Klungland, A.

10.1101/528422 — developmental biology — Posted on 2019-01-23

1068 YAP/TAZ as a Novel Regulator of cell volume

Perez Gonzalez, N. A.; Rochman, N. D.; Yao, K.; Tao, J.; Tran Le, M.-T.; Flanary, S.; Sablich, L.; Toler, B.; Crentsil, E.; Takaesu, F.; Lambrus, B.; Huang, J.; Fu, V.; Holland, A.; An, S.; Wirtz, D.; Guan, K.-L.; Sun, S.

10.1101/528133 — bioengineering — Posted on 2019-01-23

1069 New modular assays for the quantitative study of skylight navigation in flying flies

Mathejczyk, T. F.; Wernet, M. F.

10.1101/527945 — neuroscience — Posted on 2019-01-23

1070 Temporal gating of synaptic competition in the lateral amygdala by cannabinoid receptor modulation of the thalamic input

Drumond, A.; Madeira, N.; Fonseca, R.

10.1101/526624 — neuroscience — Posted on 2019-01-23

1071 Optimal sparse olfactory representations persist in a plastic network

Assisi, C.; Stopfer, M.; Bazhenov, M.

10.1101/528125 — neuroscience — Posted on 2019-01-23

1072 Alpha Neurofeedback Training with a portable Low-Priced and Commercially Available EEG Device Leads to Faster Alpha Enhancement.A Single-blind, Sham-feedback Controlled Study & Methodological Review

Naas, A.; Rodrigues, J.; Knirsch, J.-P.; Sonderegger, A.

10.1101/527598 — neuroscience — Posted on 2019-01-23

1073 Colocalization of IQGAP1 with DLC-1 and PLC-δ1; Its potential role in coronary spasm

Tanaka, M.; Tomita, H.; Hanada, K.; Osanai, T.; Homma, Y.; Okumura, K.

10.1101/526152 — molecular biology — Posted on 2019-01-23

1074 The genomes of polyextremophilic Cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions

Rossoni, A. W.; Price, D. C.; Seger, M.; Lyska, D.; Lammers, P.; Bhattacharya, D.; Weber, A. P. M.

10.1101/526111 — evolutionary biology — Posted on 2019-01-23

1075 Constrained actin dynamics emerges from variable compositions of actin regulatory protein complexes

Dobramysl, U.; Jarsch, I. K.; Shimo, H.; Inoue, Y.; Richier, B.; Gadsby, J. R.; Mason, J.; Walrant, A.; Butler, R.; Hannezo, E.; Simons, B. D.; Gallop, J.

10.1101/525725 — cell biology — Posted on 2019-01-23

1076 Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline

Overacker, R. D.; Banerjee, S.; Neuhaus, G. F.; Milicevic Sephton, S.; Herrmann, A.; Strother, J. A.; Brack-Werner, R.; Blakemore, P. R.; Loesgen, S.

10.1101/525105 — pharmacology and toxicology — Posted on 2019-01-23

1077 Individualised MRI training for paediatric neuroimaging in autism spectrum disorders: A child-focused approach

Pua, E. P. K.; Barton, S.; Williams, K.; Craig, J. M.; Seal, M.

10.1101/462234 — neuroscience — Posted on 2019-01-22

1078 Real-time assembly of an artificial virus elucidated at the single-particle level

Marchetti, M.; Kamsma, D.; Cazares Vargas, E.; Hernandez Garcia, A.; van der Schoot, P.; de Vries, R.; Wuite, G. J. L.; Roos, W. H.

10.1101/526046 — biophysics — Posted on 2019-01-22

1079 The impact of isoniazid preventive therapy on tuberculosis among household contacts of isoniazid-resistant patients.

Huang, C.-C.; Becerra, M. C.; Calderon, R.; Contreras, C.; Galea, J.; Grandjean, L.; Lecca, L.; Yataco, R.; Zhang, Z.; Murray, M.

10.1101/479865 — epidemiology — Posted on 2019-01-22

1080 Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques

Petrovic, J.; Zhou, Y.; Fasolino, M.; Goldman, N.; Schwartz, G.; Mumbach, M.; Nguyen, S.; Rome, K.; Sela, Y.; Zapataro, Z.; Blacklow, S.; Kruhlak, M.; Aster, J.; Shi, J.; Joyce, E.; Little, S.; Vahedi, G.; Pear, W. S.; Faryabi, R. B.

10.1101/527325 — cancer biology — Posted on 2019-01-22

1081 SGK1.1 activation causes early seizure termination via effects on M-current

Armas-Capote, N.; Maglio, L. E.; Perez-Atencio, L.; Martin-Batista, E.; Reboreda, A.; Barios, J. A.; Hernandez, G.; Alvarez de la Rosa, D.; Lamas, J. A.; Barrio, L. C.; Giraldez, T.

10.1101/520775 — neuroscience — Posted on 2019-01-22

1082 Distinct neural mechanisms meet challenges in dynamic visual attention due to either load or spatial interference

Maki-Marttunen, V.; Hagen, T.; Laeng, B.; Espeseth, T.

10.1101/472209 — neuroscience — Posted on 2019-01-22

1083 Distinctions among electroconvulsion- and proconvulsant-induced seizure discharges and native motor patterns during flight and grooming: Quantitative spike pattern analysis in Drosophila flight muscles

Lee, J.; Iyengar, A.; Wu, C.-F.

10.1101/481234 — neuroscience — Posted on 2019-01-22

1084 Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data

Cairns, J.; Orchard, W. R.; Malysheva, V.; Spivakov, M.

10.1101/526269 — bioinformatics — Posted on 2019-01-22

1085 Increased Interactivity and Improvements to the GigaScience Database, GigaDB.

Xiao, S. Z.; Armit, C.; Edmunds, S.; Goodman, L.; Li, P.; Tuli, M. A.; Hunter, C.

10.1101/465666 — scientific communication and education — Posted on 2019-01-22

1086 Coding of whisker motion across the mouse face

Severson, K. S.; Xu, D.; Yang, H.; O'Connor, D.

10.1101/402883 — neuroscience — Posted on 2019-01-22

1087 Iodine-enhanced micro-CT imaging of soft tissue on the example of peripheral nerve regeneration

Heimel, P.; Swiadek, N. V.; Slezak, P.; Kerbl, M.; Schneider, C.; Nuernberger, S.; Redl, H.; Teuschl, A. H.; Hercher, D.

10.1101/477539 — neuroscience — Posted on 2019-01-22

1088 Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome

Koehler, F.; Bormann, F.; Raddatz, G.; Gutekunst, J.; Musch, T.; Lyko, F.; Rodriguez-Paredes, M.

10.1101/520403 — cell biology — Posted on 2019-01-22

1089 Microhabitat predicts species differences in exploratory behavior in Lake Malawi cichlids

Johnson, Z. V.; Moore, E. C.; Wong, R. Y.; Godwin, J. R.; Streelman, J. T.; Roberts, R. B.

10.1101/525378 — animal behavior and cognition — Posted on 2019-01-22

1090 MultiFRAGing: Rapid and Simultaneous Genotyping of Multiple Alleles in a Single Reaction

Petree, C.; Varshney, G. K.

10.1101/523837 — molecular biology — Posted on 2019-01-22

1091 Genome rearrangements induce biofilm formation in Escherichia coli C, an old model organism with a new application in biofilm research

Krol, J. E. E.; Hall, D. C.; Balashov, S.; Pastor, S.; Siebert, J.; McCaffrey, J.; Lang, S.; Ehrlich, R.; Earl, J.; Mell, J. C.; Xiao, M.; Ehrlich, G. D.

10.1101/523134 — microbiology — Posted on 2019-01-22

1092 Host evolutionary history predicts virus prevalence across bumblebee species

Pascall, D. J.; Tinsley, M. C.; Obbard, D. J.; Wilfert, L.

10.1101/498717 — evolutionary biology — Posted on 2019-01-22

1093 Identification of Factors Complicating Bioluminescence Imaging

Yeh, H.-W.; Wu, T.; Chen, M.; Ai, H.

10.1101/511501 — biochemistry — Posted on 2019-01-22

1094 TMS-evoked EEG potentials from prefrontal and parietal cortex: reliability, site specificity, and effects of NMDA receptor blockade

Rogasch, N.; Zipser, C.; Darmani, G.; Mutanen, T. P.; Biabani, M.; Zrenner, C.; Desideri, D.; Belardinelli, P.; Müller-Dahlhaus, F.; Ziemann, U.

10.1101/480111 — neuroscience — Posted on 2019-01-22

1095 Pioneer and nonpioneer cooperation drives lineage specific chromatin opening

Mayran, A.; Sochodolsky, K.; Khetchoumian, K.; Harris, J.; Gauthier, Y.; Bemmo, A.; Balsalobre, A.; Drouin, J.

10.1101/472647 — genomics — Posted on 2019-01-22

1096 Quantifying the mechanics and growth of cells and tissues in 3D using high resolution computational models.

Van Liedekerke, P.; Neitsch, J.; Johann, T.; Warmt, E.; Gonzales Valverde, I.; Grosser, S.; Hoehme, S.; Kaes, J.; Drasdo, D.

10.1101/470559 — bioengineering — Posted on 2019-01-22

1097 Computational drug repositioning of bortezomib to reverse metastatic effect of GALNT14 in lung cancer

Kwon, O.-S.; Lee, H.; Kong, H.-J.; Park, J. E.; Lee, W.; Kang, S.; Kim, M.; Kim, W.; Cha, H.-J.

10.1101/394163 — pharmacology and toxicology — Posted on 2019-01-22

1098 The primary afferent activity cannot capture the dynamical features of muscle activity during reaching movements.

Hardesty, R. L.; Boots, M. T.; Yakovenko, S.; Gritsenko, V.

10.1101/138859 — neuroscience — Posted on 2019-01-22

1099 Competing evolutionary paths in growing populations with applications to multidrug resistance

Nicholson, M. D.; Antal, T.

10.1101/415208 — evolutionary biology — Posted on 2019-01-22

1100 Aberrant Clonal Hematopoiesis Following Lentiviral Transduction of HSPC in a Rhesus Macaque

Espinoza, D. A.; Fan, X.; Yang, D.; Cordes, S. F.; Truitt, L. L.; Calvo, K. R.; Yabe, I. M.; Demirci, S.; Hope, K. J.; Hong, S. G.; Krouse, A.; Metzger, M.; Bonifacino, A.; Lu, R.; Uchida, N.; Tisdale, J. F.; Wu, X.; DeRavin, S. S.; Malech, H. L.; Donahue, R. E.; Wu, C.; Dunbar, C. E.

10.1101/525691 — molecular biology — Posted on 2019-01-22

1101 Towards reliable named entity recognition in the biomedical domain

Giorgi, J.; Bader, G.

10.1101/526244 — bioinformatics — Posted on 2019-01-22

1102 Splicing buffers suboptimal codon usage in human cells

Mordstein, C.; Savisaar, R.; Young, R. S.; Bazile, J.; Talmane, L.; Luft, J.; Liss, M.; Taylor, M. S.; Hurst, L. D.; Kudla, G.

10.1101/527440 — synthetic biology — Posted on 2019-01-22

1103 Paternally-acting canonical RNA-directed DNA methylation pathway genes sensitize Arabidopsis endosperm to paternal dosage

Satyaki, R. P.; Gehring, M.

10.1101/527853 — plant biology — Posted on 2019-01-22

1104 Cell aggregation and aerobic respiration facilitate survival of Zymomonas mobilis ZM4 in an aerobic minimal medium

Jones-Burrage, S. E.; Kremer, T. A.; McKinlay, J. B.

10.1101/526699 — microbiology — Posted on 2019-01-22

1105 The response to the DNA damaging agent methyl methanesulfonate in a fungal plant pathogen

Milo, S.; Pareek, M.; Delulio, G.; Almog, Y.; Anand, G.; Ma, L.-J.; Covo, S.

10.1101/527218 — microbiology — Posted on 2019-01-22

1106 Direct conversion of human fibroblasts to liver cancer cells

Sahu, B.; Pihlajamaa, P.; Zhang, K.; Cervera, A.; Hautaniemi, S.; Taipale, J.

10.1101/525600 — cancer biology — Posted on 2019-01-22

1107 Genetic instability as a driver for immune surveillance

Aguade, G.; Sole, R.

10.1101/527689 — systems biology — Posted on 2019-01-22

1108 Gibbs Free Energy, a thermodynamic measure of protein-protein interactions, correlates with neurologic disability

Keegan, M.; Siegelmann, H. T.; Rietman, E. A.; Klement, G. L.

10.1101/527820 — biophysics — Posted on 2019-01-22

1109 Integration of Mouse and Human Single-cell RNA Sequencing Infers Spatial Cell-type Composition in Human Brains

Johnson, T. S.; Abrams, Z. B.; Helm, B. R.; Neidecker, P.; Machiraju, R.; Zhang, Y.; Huang, K.; Zhang, J.

10.1101/527499 — bioinformatics — Posted on 2019-01-22

1110 Attentional amplification of neural codes for number independent of other quantities along the dorsal visual stream

Castaldi, E.; Piazza, M.; Dehaene, S.; Vignaud, A.; Eger, E.

10.1101/527119 — neuroscience — Posted on 2019-01-22

1111 Characterizing blood modular transcriptional repertoire perturbations in patients with RSV infection: a hands-on workshop using public datasets as a source of training material

Rinchai, D.; Konza, O.; Hassler, S.; Martina, F.; Mejias, A.; Ramilo, O.; Bedognetti, D.; Mariotti-Ferrandiz, E.; Klatzmann, D.; Chaussabel, D.

10.1101/527812 — immunology — Posted on 2019-01-22

1112 Placental effects on maternal brain revealed by disrupted placental gene expression in mouse hybrids

Arevalo, L.; Campbell, P.

10.1101/527143 — evolutionary biology — Posted on 2019-01-22

1113 Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models

Waaler, J.; Mygland, L.; Tveita, A.; Strand, M. F.; Solberg, N. T.; Angell Olsen, P.; Lund, K.; Alam Brinch, S.; Lycke, M.; Dybing, E.; Nygaard, V.; Boe, S. L.; Heintz, K.-M.; Hovig, E.; Hammarstrom, C.; Corthay, A.; Krauss, S.

10.1101/526343 — cancer biology — Posted on 2019-01-22

1114 Social tolerance in Octopus laqueus - a maximal entropy model

Edsinger, E.; Pnini, R.; Ono, N.; Yanagisawa, R.; Dever, K.; Miller, J.

10.1101/526905 — animal behavior and cognition — Posted on 2019-01-22

1115 Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock

Ray, J.; Munn, P. R.; Vihervaara, A.; Ozer, A.; Danko, C. G.; Lis, J. T.

10.1101/527838 — molecular biology — Posted on 2019-01-22

1116 A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

He, Y.; Chang, Y.; Bao, L.; Yu, M.; Li, R.; Niu, J.; Fan, G.; Song, W.; Seim, I.; Qin, Y.; Li, X.; Liu, J.; Kong, X.; Peng, M.; Sun, M.; Wang, M.; Qu, J.; Wang, X.; Liu, X.; Wu, X.; Zhao, X.; Wang, X.; Zhao, Y.; Guo, J.; Liu, Y.; Liu, K.; Wang, Y.; Zhang, H.; Liu, L.; Wang, M.; Yu, H.; Wang, X.; Cheng, J.; Wang, Z.; Xu, X.; Wang, J.; Yang, H.; Lee, S. M.-Y.; Liu, X.; Zhang, Q.; Qi, J.

10.1101/527036 — genomics — Posted on 2019-01-22

1117 Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions

Schotanus, K.; Heitman, J.

10.1101/526962 — genetics — Posted on 2019-01-22

1118 DNA methylation directs polycomb-dependent 3D genome re- organisation in naive pluripotency

McLaughlin, K. A.; Flyamer, I. M.; Thomson, J. P.; Mjoseng, H. K.; Shukla, R.; Williamson, I.; Grimes, G. R.; Illingworth, R. S.; Adams, I. R.; Pennings, S.; Meehan, R. R.; Bickmore, W. A.

10.1101/527309 — cell biology — Posted on 2019-01-22

1119 Individualised MRI training for paediatric neuroimaging in autism spectrum disorders: A child-focused approach

Pua, E. P. K.; Barton, S.; Williams, K.; Craig, J. M.; Seal, M.

10.1101/462234 — neuroscience — Posted on 2019-01-22

1120 The Malaria Cell Atlas: a comprehensive reference of single parasite transcriptomes across the complete Plasmodium life cycle

Howick, V. M.; Russell, A.; Andrews, T.; Heaton, H.; Reid, A. J.; Natarajan, K. N.; Butungi, H.; Metcalf, T.; Verzier, L. H.; Rayner, J.; Berriman, M.; Herren, J.; Billker, O.; Hemberg, M.; Talman, A.; Lawniczak, M.

10.1101/527556 — genomics — Posted on 2019-01-22

1121 A potential role for the gut microbiota in the specialisation of Drosophila sechellia to its toxic host noni (Morinda citrifolia)

Heys, C.; Fisher, A. M.; Dewhurst, A. D.; Lewis, Z.; Lize, A.

10.1101/526517 — evolutionary biology — Posted on 2019-01-22

1122 Emergence of metabolic landscapes in yeast monolayer colonies

Marinkovic, Z. S.; Vulin, C.; Acman, M.; Song, X.; Di Meglio, J. M.; Lindner, A.; Hersen, P.

10.1101/527846 — biophysics — Posted on 2019-01-22

1123 Dynamical reorganization of transcriptional events governs robust Nanog heterogeneity

Samanta, T.; Kar, S.

10.1101/527747 — bioinformatics — Posted on 2019-01-22

1124 Microhabitat predicts species differences in exploratory behavior in Lake Malawi cichlids

Johnson, Z. V.; Moore, E. C.; Wong, R. Y.; Godwin, J. R.; Streelman, J. T.; Roberts, R. B.

10.1101/525378 — animal behavior and cognition — Posted on 2019-01-22

1125 Organ-wide and ploidy-dependent regulations both contribute to cell size determination: evidence from a computational model of tomato fruit

Baldazzi, V.; Valsesia, P.; Genard, M.; Bertin, N.

10.1101/450916 — plant biology — Posted on 2019-01-22

1126 Glial Ca2+ Signaling Links Endocytosis to K+ Buffering around Neuronal Somas to Regulate Excitability

Weiss, S.; Melom, J. E.; Ormerod, K. G.; Zhang, Y. V.; Littleton, J. T.

10.1101/426130 — neuroscience — Posted on 2019-01-22

1127 Macroevolutionary diversification rates show time-dependency

Henao Diaz, L. F.; Harmon, L. J.; Sugawara, M. T. C.; Miller, E. I.; Pennell, M. W.

10.1101/396598 — evolutionary biology — Posted on 2019-01-22

1128 Geography, not food availability, reflects compositional differences in the bacterial communities associated with larval sea urchins

Carrier, T.; Dupont, S.; Reitzel, A.

10.1101/394486 — ecology — Posted on 2019-01-22

1129 Widespread transcriptional scanning in the testis modulates gene evolution rates

Xia, B.; Yan, Y.; Baron, M.; Wagner, F.; Barkley, D.; Chiodin, M.; Kim, S. Y.; Keefe, D. L.; Alukal, J. P.; Boeke, J. D.; Yanai, I.

10.1101/282129 — evolutionary biology — Posted on 2019-01-22

1130 Towards a human ecology of olfaction in the built environment

Hoover, K. C.; Roberts, J.; Fedurek, P.; Botescu, D.; Berbesque, J. C.

10.1101/270744 — ecology — Posted on 2019-01-22

1131 Adaptation of olfactory receptor abundances for efficient coding

Tesileanu, T.; Cocco, S.; Monasson, R.; Balasubramanian, V.

10.1101/255547 — neuroscience — Posted on 2019-01-22

1132 A deep learning system can accurately classify primary and metastatic cancers based on patterns of passenger mutations

Jiao, W.; Atwal, G.; Polak, P.; Karlic, R.; Cuppen, E.; Danyi, A.; de Ridder, J.; van Herpen, C.; Lolkema, M. P.; Steeghs, N.; Getz, G.; Morris, Q. D.; Stein, L. D.; PCAWG Pathology & Clinical Correlates Working Grp, ; ICGC/TCGA Pan-cancer Analysis of Whole Genomes Net,

10.1101/214494 — cancer biology — Posted on 2019-01-22

1133 Super-resolving light fields in microscopy: depth from disparity

Sims, R. R.; Abdul Rehman, S.; Lenz, M. O.; Muresan, L.; O'Holleran, K.

10.1101/527432 — bioengineering — Posted on 2019-01-22

1134 Thyroid hormone regulates distinct paths to maturation in pigment cell lineages

Saunders, L.; Mishra, A.; Aman, A. J.; Lewis, V.; Toomey, M. B.; Packer, J.; McFaline-Figueroa, J.; Qiu, X.; Corbo, J. C.; Trapnell, C.; Parichy, D. M.

10.1101/527341 — developmental biology — Posted on 2019-01-22

1135 Mechanical and thermodynamic properties of Aβ42, Aβ40 and α-synuclein fibrils: A coarse-grained method to complement experimental studies

Poma, A.; Vargas Guzman, H. A.; Li, M. S.; Theodorakis, P.

10.1101/527242 — biophysics — Posted on 2019-01-22

1136 Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes

Yeo, W. L.; Heng, E.; Tan, L. L.; Lim, Y. W.; Lim, Y. H.; Hoon, S.; Zhao, H.; Zhang, M. M.; Wong, F. T.

10.1101/526996 — synthetic biology — Posted on 2019-01-22

1137 C99, not beta-amyloid, is associated with selective death of vulnerable neurons in Alzheimer's disease.

Pulina, M.; Hopkins, M.; Haroutunian, V.; Greengard, P.; Bustos, V.

10.1101/527572 — neuroscience — Posted on 2019-01-22

1138 The variability of expression of many genes and most functional pathways is observed to increase with age in brain transcriptome data

Kedlian, V. R.; Donertas, H. M.; Thornton, J. M.

10.1101/526491 — genomics — Posted on 2019-01-22

1139 Maximum entropy models elucidate the contribution of metabolic traits to patterns of community assembly

Bertram, J.; Newman, E. A.; Dewar, R.

10.1101/526764 — ecology — Posted on 2019-01-22

1140 Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques

Petrovix, J.; Zhou, Y.; Fasolino, M.; Goldman, N.; Schwartz, G.; Mumbach, M.; Nguyen, S.; Rome, K.; Sela, Y.; Zapataro, Z.; Blacklow, S.; Kruhlak, M.; Aster, J.; Shi, J.; Joyce, E.; Little, S.; Vahedi, G.; Pear, W. S.; Faryabi, R. B.

10.1101/527325 — cancer biology — Posted on 2019-01-22

1141 Linking lineage and population observables in biological branching processes

Garcia-Garcia, R.; Genthon, A.; Lacoste, D.

10.1101/527291 — biophysics — Posted on 2019-01-22

1142 Characterisation of type 2 diabetes progression with regulatory network

Barrera, M.; Hiriart, M.; Cocho, G.; Villarreal, C.

10.1101/526954 — systems biology — Posted on 2019-01-22

1143 ABC transporters alter plant-microbe-parasite interactions in the rhizosphere

Cox, D.; Dyer, S.; Weir, R.; Cheseto, X.; Sturrock, M.; Coyne, D.; Torto, B.; Maule, A. G.; Dalzell, J. J.

10.1101/526582 — plant biology — Posted on 2019-01-22

1144 Antarctica's wilderness has declined to the exclusion of biodiversity

Leihy, R. I.; Coetzee, B. W. T.; Morgan, F.; Raymond, B.; Shaw, J. D.; Terauds, A.; Chown, S. L.

10.1101/527010 — ecology — Posted on 2019-01-22

1145 The biofilm matrix scaffold of Pseudomonas species consists of non-canonically base paired extracellular DNA and RNA

Seviour, T. W.; Winnerdy, F. R.; Lan Li, W.; Xiangyan, S.; Mugunthan, S.; Kohli, G. S.; Shewan, H. M.; Stokes, J.; Rice, S. A.; Phan, A.-T.; Kjelleberg, S.

10.1101/527267 — biochemistry — Posted on 2019-01-22

1146 Phase separation provides a mechanism to reduce noise in cells

Oltsch, F.; Klosin, A.; Julicher, F.; Hyman, A. A.; Zechner, C.

10.1101/524231 — biophysics — Posted on 2019-01-22

1147 E2M: A Deep Learning Framework for Associating Combinatorial Methylation Patterns with Gene Expression

Peng, J.; Ochoa, I.; Milenkovic, O.

10.1101/527044 — bioinformatics — Posted on 2019-01-22

1148 Inferring tumor evolution from longitudinal samples

Myers, M. A.; Satas, G.; Raphael, B. J.

10.1101/526814 — bioinformatics — Posted on 2019-01-22

1149 Vibrio cholerae MARTX toxin multifunctionality silences inflammatory response to toxin mediated cytoskeletal collapse

Woida, P. J.; Satchell, K. J. F.

10.1101/526616 — microbiology — Posted on 2019-01-22

1150 Transmission bias's fundamental role in biodiversity change

Godsoe, W.; Eisen, K.; Stanton, D.

10.1101/527028 — ecology — Posted on 2019-01-22

1151 Folding landscape of a parallel G-quadruplex

Gray, R. D.; Trent, J. O.; Arumugam, S.; Chaires, J.

10.1101/526780 — biophysics — Posted on 2019-01-22

1152 Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data

Cairns, J.; Orchard, W. R.; Malysheva, V.; Spivakov, M.

10.1101/526269 — bioinformatics — Posted on 2019-01-22

1153 Human Cytomegalovirus Remodeling of Lipid Metabolism Requires pUL37x1

Purdy, J. G.; Xi, Y.; Harwood, S.; Wise, L.

10.1101/526228 — microbiology — Posted on 2019-01-22

1154 Disease-causing mutations in subunits of OXPHOS complex I affect their physical interactions

Barshad, G.; Zlotinkov-Poznianski, N.; Gal, L.; Schuldiner, M.; Mishmar, D.

10.1101/526020 — genomics — Posted on 2019-01-22

1155 Glial response to hypoxia in trachealess mutants induces synapse remodeling.

Chien, C.-T.; Chen, P.-Y.; Tsai, Y.-W.; Giangrande, A.

10.1101/527671 — genetics — Posted on 2019-01-22

1156 Ecological specificity of the metagenome in a set of lower termite species supports contribution of the microbiome to adaptation of the host

Waidele, L.; Korb, J.; Voolstra, C. R.; Dedeine, F.; Staubach, F.

10.1101/526038 — evolutionary biology — Posted on 2019-01-22

1157 Mismatches between niches and geographic ranges of plants depend on life history traits

Pagel, J.; Treurnicht, M.; Bond, W. J.; Kraaij, T.; Nottebrock, H.; Schutte-Vlok, A.; Tonnabel, J.; Esler, K. J.; Schurr, F. M.

10.1101/526251 — ecology — Posted on 2019-01-22

1158 Fate plasticity and reprogramming in genetically distinct populations of Danio leucophores

Lewis, V.; Saunders, L.; Larson, T. A.; Bain, E.; Sturiale, S.; Gur, D.; Chowdhury, S.; Flynn, J.; Allen, M.; Deheyn, D.; Lee, J.; Simon, J.; Lippincott-Schwartz, J.; Raible, D.; Parichy, D.

10.1101/526475 — developmental biology — Posted on 2019-01-22

1159 A Bayesian approach for correcting Tn5 transposition bias in ATAC-seq footprinting

Viswanadham, V. V.; Mahajan, V. S.; Pillai, S.

10.1101/525808 — bioinformatics — Posted on 2019-01-22

1160 Unsupervised Machine Learning for Analysis of Coexisting Lipid Phases and Domain Growth in Biological Membranes

Lopez, C. A.; Vesselinov, V. V.; Gnanakaran, S.; Alexandrov, B. S.

10.1101/527630 — bioinformatics — Posted on 2019-01-22

1161 Validation of a novel milk progesterone-based tool to monitor luteolysis in dairy cows. Timing of the alerts and robustness against missing values

Adriaens, I.; Martin, O.; Saeys, W.; De Ketelaere, B.; Friggens, N. C.; Aernouts, B.

10.1101/526095 — bioengineering — Posted on 2019-01-22

1162 Multi-frequency tACS has lasting effects on neural synchrony and audiovisual responses

Bockhorst, T.; Ahlbeck, J.; Pieper, F.; Engler, G.; Engel, A. K.

10.1101/526087 — neuroscience — Posted on 2019-01-22

1163 Association between premorbid body mass index and amyotrophic lateral sclerosis: causal inference through genetic approaches

Zeng, P.; Yu, X.; Xu, H.

10.1101/526186 — neuroscience — Posted on 2019-01-22

1164 Platelet-neutrophil aggregates promote skin pathology in psoriasis

10.1101/526236 — immunology — Posted on 2019-01-22

1165 Surprising impacts of crossover interference and sex-specific genetic maps on identical by descent distributions

Caballero, M.; Seidman, D. N.; Dyer, T. D.; Lehman, D. M.; Curran, J. E.; Duggirala, R.; Blangero, J.; Williams, A. L.

10.1101/527655 — genetics — Posted on 2019-01-22

1166 Convergent inactivation of the skin-specific C-C motif chemokine ligand 27 in mammalian evolution

Lopes-Marques, M.; Alves, L. Q.; Fonseca, M.; Secci-Petretto, G.; Machado, A. M.; Ruivo, R.; Castro, F.

10.1101/526145 — evolutionary biology — Posted on 2019-01-22

1167 Discoidan Domain Receptor 1 (DDR1) Tyrosine Kinase is Upregulated in PKD Kidneys But Does Not Play a Role in the Pathogenesis of Polycystic Kidney Disease

Skolnik, E. Y.; Soomro, I.; Hong, A.; Li, Z.; Duncan, J.; ALL ON MAIN LIST,

10.1101/527614 — cell biology — Posted on 2019-01-22

1168 Comprehensive identification of survival-associated genes for cancers

Liu, H.; Luo, K.; Li, H.; Sun, X.

10.1101/526285 — cancer biology — Posted on 2019-01-22

1169 Chromatin maturation of the HIV-1 provirus in primary resting CD4+ T cells

Lindqvist, B.; Svensson Akusjarvi, S.; Sonnerborg, A.; Dimitriou, M.; Svensson, J. P.

10.1101/526053 — microbiology — Posted on 2019-01-22

1170 Assessing chromatin accessibility in maize using ATAC-seq

Lee, Y.-J.; Chang, P.; Lu, J.-H.; Chen, P.-Y.; Wang, C.-J. R.

10.1101/526079 — genomics — Posted on 2019-01-22

1171 Phenotypic determinism and contingency in the evolution of hypothetical tree-like organisms

Nonoyama, T.; Chiba, S.

10.1101/527622 — evolutionary biology — Posted on 2019-01-22

1172 Single-cell analysis reveals the KIT D816V mutation in hematopoietic stem and progenitor cells in systemic mastocytosis

Grootens, J.; Ungerstedt, J. S.; Ekoff, M.; Rönnberg, E.; Klimkowska, M.; Amini, R.-M.; Arock, M.; Söderlund, S.; Mattsson, M.; Nilsson, G.; Dahlin, J. S.

10.1101/394304 — immunology — Posted on 2019-01-22

1173 Ancestral admixture is the main determinant of global biodiversity in fission yeast

Tusso, S.; Nieuwenhuis, B. P. S.; Sedlazeck, F. J.; Davey, J. W.; Jeffares, D.; Wolf, J. B. W.

10.1101/415091 — evolutionary biology — Posted on 2019-01-22

1174 Handling noise in protein interaction networks

Brito Correia, F.; Coelho, E. D.; Oliveira, J. L.; Arrais, J. P.

10.1101/527606 — bioinformatics — Posted on 2019-01-22

1175 A divergent CheW confers plasticity to nucleoid-associated chemosensory arrays

Guiseppi, A.; Vicente, J.-J.; Barneoud, A.; Moine, A.; Espinosa, L.; Basse, M.-J.; Molle, V.; Mignot, T.; Roche, P.; Mauriello, E.

10.1101/239202 — microbiology — Posted on 2019-01-22

1176 Krüppel-like factor gene function in the ctenophore Mnemiopsis suggests an ancient role in promoting cell proliferation in metazoan stem cell niches

Presnell, J. S.; Browne, W. E.

10.1101/527002 — developmental biology — Posted on 2019-01-21

1177 Spatial Asymmetries of the Prophase Nucleus Regulate Dynein Recruitment to Ensure Mitotic Fidelity

Nunes, V.; Dantas, M.; Vitiello, E.; Wang, I.; Carpi, N.; Balland, M.; Piel, M.; Aguiar, P.; Maiato, H.; Ferreira, J. G.

10.1101/526939 — cell biology — Posted on 2019-01-21

1178 Advances in Geometric Techniques for Analyzing Blebbing in Chemotaxing Dictyostelium Cells

Santiago, Z.; Loustau, J.; Meretzky, D.; Rawal, D.; Brazill, D.

10.1101/526608 — cell biology — Posted on 2019-01-21

1179 Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells

Baudoin, N. C.; Soto, K.; Martin, O.; Nicholson, J. M.; Chen, J.; Cimini, D.

10.1101/526731 — cell biology — Posted on 2019-01-21

1180 Multimodal gradients across mouse cortex

Fulcher, B. D.; Murray, J. D.; Zerbi, V.; Wang, X.-J.

10.1101/393215 — neuroscience — Posted on 2019-01-21

1181 Real-time assembly of an artificial virus elucidated at the single-particle level

Marchetti, M.; Kamsma, D.; Cazares Vargas, E.; Hernandez Garcia, A.; van der Schoot, P.; de Vries, R.; Wuite, G. J. L.; Roos, W. H.

10.1101/526046 — biophysics — Posted on 2019-01-21

1182 MYOSIN VA TRANSPORT OF LIPOSOMES IN THREE-DIMENSIONAL ACTIN NETWORKS IS MODULATED BY ACTIN FILAMENT DENSITY, POSITION, AND POLARITY

Lombardo, A. T.; Nelson, S. R.; Kennedy, G. G.; Trybus, K. M.; Walcott, S.; Warshaw, D. M.

10.1101/526640 — biophysics — Posted on 2019-01-21

1183 Hippocampal transcriptomic responses to cellular dissociation

Harris, R. M.; Kao, H.-Y.; Alarcon, J. M.; Hofmann, H. A.; Fenton, A.

10.1101/153585 — neuroscience — Posted on 2019-01-21

1184 Epigenetic suppression of interferon lambda receptor expression leads to enhanced HuNoV replication in vitro

Arthur, S. E.; Sorgeloos, F.; Hosmillo, M.; Goodfellow, I.

10.1101/523282 — microbiology — Posted on 2019-01-21

1185 Visual modelling supports the potential for prey detection by means of diurnal active photolocation in a small cryptobenthic fish

Bitton, P.-P.; Yun Christmann, S. A.; Santon, M.; Harant, U. K.; Michiels, N. K.

10.1101/338640 — zoology — Posted on 2019-01-21

1186 Penalized matrix decomposition for denoising, compression, and improved demixing of functional imaging data

Buchanan, E. K.; Kinsella, I.; Zhou, D.; Zhu, R.; Zhou, P.; Gerhard, F.; Ferrante, J.; Ma, Y.; Kim, S.; Shaik, M.; Liang, Y.; Lu, R.; Reimer, J.; Fahey, P.; Muhammad, T.; Dempsey, G.; Hillman, E.; Ji, N.; Tolias, A.; Paninski, L.

10.1101/334706 — neuroscience — Posted on 2019-01-21

1187 Loss of EPAC2 results in altered synaptic composition of dendritic spines and excitatory and inhibitory balance

Jones, K. A.; Sumiya, M.; Woolfrey, K. M.; Srivastava, D. P.; Penzes, P.

10.1101/526772 — neuroscience — Posted on 2019-01-21

1188 Natural selection subsumes and unites multiple theories of perceptual compression

Quintanar-Zilinskas, V.

10.1101/507459 — neuroscience — Posted on 2019-01-21

1189 Active membrane conductances and morphology of a collision detection neuron broaden its impedance profile and improve membrane synchrony

Dewell, R.; Gabbiani, F.

10.1101/454702 — neuroscience — Posted on 2019-01-21

1190 Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking

Lorenz-Guertin, J. M.; Bambino, M. J.; Das, S.; Weintraub, S. T.; Jacob, T. C.

10.1101/514133 — neuroscience — Posted on 2019-01-21

1191 Caveolae and scaffold detection from single molecule localization microscopy data using deep learning

Khater, I. M.; Aroca-Ouellette, S. T.; Meng, F.; Nabi, I. R.; Hamarneh, G.

10.1101/526327 — molecular biology — Posted on 2019-01-21

1192 ICA512 RESP18 homology domain is a protein condensing factor and insulin fibrillation inhibitor

Toledo, P. L.; Torkko, J. M.; Müller, A.; Wegbrod, C.; Sönmez, A.; Solimena, M.; Ermacora, M. R.

10.1101/521351 — biophysics — Posted on 2019-01-21

1193 Transcranial ultrasound selectively biases decision-making in primates

Kubanek, J.; Brown, J.; Ye, P.; Pauly, K. B.; Moore, T.; Newsome, W.

10.1101/486134 — neuroscience — Posted on 2019-01-21

1194 A non-Lamarckian model for the inheritance of the epigenetically-coded phenotypic characteristics: a new paradigm for Genetics, Genomics and, above all, Ageing studies

Marsellach, X.

10.1101/492280 — genetics — Posted on 2019-01-21

1195 Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome

Koehler, F.; Bormann, F.; Raddatz, G.; Gutekunst, J.; Musch, T.; Lyko, F.; Rodriguez-Paredes, M.

10.1101/520403 — cell biology — Posted on 2019-01-21

1196 A de novo peroxidase is also a promiscuous yet stereoselective carbene transferase

Stenner, R.; Steventon, J.; Seddon, A.; Anderson, J. L. R.

10.1101/328484 — synthetic biology — Posted on 2019-01-21

1197 A voltage-dependent depolarization induced by low external glucose in neurons of the nucleus of the tractus solitarius of rats: interaction with KATP channels regulated by external glucose.

Murat, C. d. B.; Leao, R.

10.1101/328658 — physiology — Posted on 2019-01-21

1198 Smoking and the risk for bipolar disorder: causal evidence from a bidirectional Mendelian randomization study

Vermeulen, J.; Wootton, R.; Treur, J.; Sallis, H.; Jones, H.; Zammit, S.; van den Brink, W.; Goodwin, G.; de Haan, L.; Munafo, M.

10.1101/522268 — neuroscience — Posted on 2019-01-21

1199 Theory of mechano-chemical patterning in biphasic biological tissues

Recho, P.; Hallou, A.; Hannezo, E.

10.1101/484345 — biophysics — Posted on 2019-01-21

1200 A new actin depolymerase: a catch bond Myosin 1 motor

Pernier, J.; Kusters, R.; Bousquet, H.; Lagny, T.; Morchain, A.; Joanny, J.-F.; Bassereau, P.; Coudrier, E.

10.1101/375923 — biophysics — Posted on 2019-01-21

1201 Evolutionary constraints on the complexity of genetic regulatory networks allow predictions of the total number of genetic interactions

Campos-Gonzalez, A. I.; Freyre-Gonzalez, J. A.

10.1101/486647 — systems biology — Posted on 2019-01-21

1202 Widespread selection for high and low secondary structure in coding sequences across all domains of life

Gebert, D.; Jehn, J.; Rosenkranz, D.

10.1101/524538 — evolutionary biology — Posted on 2019-01-21

1203 Different molecular signatures in lung cancer types from integrative bioinformatic analyses of RNASeq data

Lucchetta, M.; da Piedade, I.; Mounir, M.; Vabistsevits, M.; Terkelsen, T.; Papaleo, E.

10.1101/501569 — bioinformatics — Posted on 2019-01-21

1204 Representations of evidence for a perceptual decision in the human brain

Bitzer, S.; Park, H.; Maess, B.; von Kriegstein, K.; Kiebel, S.

10.1101/350876 — neuroscience — Posted on 2019-01-21

1205 Tracing the Ancestry of Operons in Bacteria

Nguyen, H. N.; Jain, A.; Eulenstein, O.; Friedberg, I.

10.1101/212886 — evolutionary biology — Posted on 2019-01-21

1206 Hedgehog signaling controls progenitor differentiation timing

Rowton, M.; Hoffmann, A. D.; Steimle, J. D.; Hur, S.; Yang, X. H.; Guzzetta, A.; Lazarevic, S.; Kim, C.; Deng, N.; Lu, E.; Jacobs-Li, J.; Yu, S.; Koska, M.; Hanson, E.; Perez-Cervantes, C.; Chan, S. S.-K.; Ikegami, K.; Garry, D. J.; Kyba, M.; Moskowitz, I. P.

10.1101/270751 — developmental biology — Posted on 2019-01-21

1207 Microscopy-based chromosome conformation capture enables simultaneous visualization of genome organization and transcription in intact organisms

Cardozo Gizzi, A. M.; Cattoni, D. I.; Fiche, J.-B.; Espinola, S.; Gurgo, J.; Messina, O.; Houbron, C.; Ogiyama, Y.; Papadopoulos, G.-L.; Cavalli, G.; Lagha, M.; Nollmann, M.

10.1101/434266 — cell biology — Posted on 2019-01-21

1208 MutliFRAGing: Rapid and Simultaneous Genotyping of Multiple Alleles in a Single Reaction

Petree, C.; Varshney, G. K.

10.1101/523837 — molecular biology — Posted on 2019-01-21

1209 Comparative architectures of direct and social genetic effects from the genome-wide association study of 170 phenotypes in outbred laboratory mice

Baud, A.; Casale, F. P.; Nicod, J.; Stegle, O.

10.1101/302349 — genetics — Posted on 2019-01-21

1210 In vivo optochemical control of cell contractility at single cell resolution by Ca2+ induced myosin activation

Kong, D.; Lv, Z.; Häring, M.; Wolf, F.; Grosshans, J.

10.1101/255372 — developmental biology — Posted on 2019-01-21

1211 scVAE: Variational auto-encoders for single-cell gene expression data

Gronbech, C. H.; Vording, M. F.; Timshel, P. N.; Sonderby, C. K.; Pers, T. H.; Winther, O.

10.1101/318295 — bioinformatics — Posted on 2019-01-21

1212 Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides

Chang, Z.; Billmyre, R. B.; Lee, S. C.; Heitman, J.

10.1101/526459 — microbiology — Posted on 2019-01-21

1213 Kinase-independent inhibition of cyclophosphamide-induced pathways protects the ovarian reserve and prolongs fertility

Bellusci, G.; Iannizzotto, V.; Ciccone, S.; Mattiello, L.; Maiani, E.; Villani, V.; Diederich, M.; Gonfloni, S.

10.1101/526103 — cell biology — Posted on 2019-01-21

1214 Stoichiometric quantification of spatially dense assemblies with qPAINT

Baker, M.; Nieves, D. J.; Hilzenrat, G.; Berengut, J. F.; Gaus, K.; Lee, L. K.

10.1101/525345 — biophysics — Posted on 2019-01-21

1215 Modeling enamel matrix secretion in mammalian teeth

Hakkinen, T. J.; Sova, S. S.; Corfe, I. J.; Tjaderhane, L.; Hannukainen, A.; Jernvall, J.

10.1101/525162 — biophysics — Posted on 2019-01-21

1216 Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion

Chang, W. H.; Lai, A. G.

10.1101/526202 — cancer biology — Posted on 2019-01-21

1217 Intrinsic spine dynamics are critical for recurrent network learning in models with and without autism spectrum disorder

Humble, J.; Hiratsuka, K.; Kasai, H.; Toyoizumi, T.

10.1101/525980 — neuroscience — Posted on 2019-01-21

1218 Characterization of neuronal synaptopodin reveals a myosin V-dependent mechanism of synaptopodin clustering at the post-synaptic sites

Gonzalez-Gallego, J.; Konietzny, A.; Perez-Alvarez, A.; Baer, J.; Maier, U.; Drakew, A.; Hammer, J. A.; Demmers, J. A. A.; Dekkers, D. H. W.; Frotscher, M.; Kneussel, M.; Oertner, T.; Wagner, W.; Mikhaylova, M.

10.1101/526509 — neuroscience — Posted on 2019-01-21

1219 Multi-Cell ECM compaction is predictable via superposition of nonlinear cell dynamics linearized in augmented state space

Mayalu, M. N.; Kim, M.; Asada, H. H.

10.1101/526426 — systems biology — Posted on 2019-01-21

1220 Accelerated loss of hypoxia response and biased allele expression in zebrafish with Alzheimer’s disease-like mutations

Newman, M.; Moussavi Nik, H.; Sutherland, G.; Kim, W.; Halliday, G.; Jayadev, S.; Smith, C.; Kittipassorn, T.; Peet, D.; Lardelli, M.

10.1101/526277 — genomics — Posted on 2019-01-21

1221 Whole Aegilops tauschii transcriptome investigation revealed nine novel miRNAs involved in stress response

Bakhshi, B.; Mohseni Fard, E.

10.1101/525972 — molecular biology — Posted on 2019-01-21

1222 Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

Epi25 Collaborative, ; Feng, Y.-C. A.; Howrigan, D. P.; Abbott, L. E.; Tashman, K.; Cerrato, F.; Singh, T.; Heyne, H.; Byrnes, A.; Churchhouse, C.; Lal, D.; Heinzen, E. L.; Cavalleri, G. L.; Hakonarson, H.; Helbig, I.; Krause, R.; May, P.; Weckhuysen, S.; Petrovski, S.; Kamalakaran, S.; Sisodiya, S. M.; Cossette, P.; Cotsapas, C.; De Jonghe, P.; Dixon-Salazar, T.; Guerrini, R.; Kwan, P.; Marson, A. G.; Stewart, R.; Depondt, C.; Dlugos, D. J.; Scheffer, I. E.; Striano, P.; Freyer, C.; McKenna, K.; Regan, B. M.; Bellows, S. T.; Leu, C.; Bennett, C. A.; Johns, E. M. C.; Macdonald, A.; Shilling,

10.1101/525683 — genetics — Posted on 2019-01-21

1223 Elucidating small RNA pathways in Arabidopsis thaliana egg cells

Sprunck, S.; Urban, M.; Strieder, N.; Lindemeier, M.; Bleckmann, A.; Evers, M.; Hackenberg, T.; Moehle, C.; Dresselhaus, T.; Engelmann, J. C.

10.1101/525956 — plant biology — Posted on 2019-01-21

1224 Knockdown of PTOV1 and PIN1 Exhibit Common Phenotypic Anti-Cancer Effects in MDA-MB-231 Cells

Pokharel, Y. R.; Karna, S. K. L.; Ahmad, F.; Lone, B. A.

10.1101/526319 — cell biology — Posted on 2019-01-21

1225 DSNetwork: An integrative approach to visualize predictions of variants’ deleteriousness

Lemacon, A.; Scott-Boyer, M.-P.; Soucy, P.; Ongaro-Carcy, R.; Simard, J.; Droit, A.

10.1101/526335 — bioinformatics — Posted on 2019-01-21

1226 A sustained small increase in NOD1 expression promotes ligand-independent oncogenic activity

Rommereim, L. M.; Akhade, A. S.; Dutta, B.; Hutcheon, C.; Lounsbury, N. W.; Rostomily, C. C.; Savan, R.; Fraser, I. D. C.; Germain, R. N.; Subramanian, N.

10.1101/518886 — systems biology — Posted on 2019-01-21

1227 A High-Throughput Physiological Functional Phenotyping System for Time- and Cost-Effective Screening of Potential Biostimulants

Dalal, A.; Bourstein, R.; Haish, N.; Shenhar, I.; Wallach, R.; Moshelion, M.

10.1101/525592 — plant biology — Posted on 2019-01-21

1228 Observing the origins of human brain development: Automated processing of fetal fMRI

Rutherford, S.; Sturmfels, P.; Angstadt, M.; Hect, J.; Wiens, J.; van den Heuval, M. I.; Scheinost, D.; Thomason, M.; Sripada, C.

10.1101/525386 — neuroscience — Posted on 2019-01-21

1229 The diversity, evolution and ecology of Salmonella in venomous snakes

Pulford, C. V.; Wenner, N.; Redway, M. L.; Rodwell, E. V.; Webster, H. J.; Escudero, R.; Kröger, C.; Canals, R.; Rowe, W.; Lopez, J.; Hall, N.; Rowley, P. D.; Timofte, D.; Harrison, R. A.; Baker, K. S.; Hinton, J. C. D.

10.1101/526442 — microbiology — Posted on 2019-01-21

1230 Data driven analysis reveals shared transcriptome response and immune cell composition across aetiologies of critical illness.

Zador, Z.; Landry, A.; Balas, M.; Marshall, J. C.; Cusimano, M. D.

10.1101/525865 — immunology — Posted on 2019-01-21

1231 Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition

Sanghera, D. K.; Hopkins, R.; Malone-Perez, M. W.; Bejar, C.; Tan, C.; Mussa, H.; Whitby, P.; Rao, C. V.; Fung, K. A.; Lightfoot, S.; Frazer, J. K.

10.1101/526350 — genetics — Posted on 2019-01-21

1232 The response of genes and pathways of immunological system induced by irradiation

Ribeiro, F. M.; Silveira, D. A.; De Mattos, V. L. D.; Simao, E. M.; Goes, E. G.

10.1101/526384 — biophysics — Posted on 2019-01-21

1233 Registration for Image-Based Transcriptomics: Parametric Signal Features and Multivariate Information Measures

Chen, R.; Das, A. B.; Varshney, L. R.

10.1101/521898 — bioinformatics — Posted on 2019-01-21

1234 Why Pacing Frequency Affects the Production of Early Afterdepolarizations in Cardiomyocytes: An Explanation Revealed by Slow/Fast Analysis of a Minimal Model

Vo, T.; Bertram, R.

10.1101/526418 — systems biology — Posted on 2019-01-21

1235 Synapse-specific Opioid Modulation of Thalamo-cortico-striatal Circuits

Birdsong, W. T.; Jongbloets, B. C.; Engeln, K. A.; Wang, D.; Scherrer, G.; Mao, T.

10.1101/525782 — neuroscience — Posted on 2019-01-21

1236 Learning in visual regions as support for the bias in future value-driven choice

Jahfari, S.; Theeuwes, J.; Knapen, T.

10.1101/523340 — neuroscience — Posted on 2019-01-21

1237 Genetic diversity analysis of an isolate of microsporidia infesting Athetis lepigone

Zhang, H.; Song, J.; Yang, Y.; An, J.; Ma, H.; li, y.

10.1101/526368 — microbiology — Posted on 2019-01-21

1238 Tad pili play a dynamic role in Caulobacter crescentus surface colonization

Jenal, U.; Sangermani, M.; Hug, I.; Sauter, N.; Pfohl, T.

10.1101/526160 — microbiology — Posted on 2019-01-21

1239 EVALUATION OF FEMALE SEXUAL FUNCTION IN PERSONS WITH TYPE 2 DIABETES MELLITUS SEEN IN A TERTIARY HOSPITAL IN SOUTH EAST NIGERIA WITH EMPHASIS ON ITS FREQUENCY AND PREDICTORS

Ezeani, I.; Onyeonoro, U.; Ugwu, E.

10.1101/526301 — immunology — Posted on 2019-01-21

1240 Detection of cross-contamination and strong mitonuclear discordance in two species groups of sawfly genus Empria (Hymenoptera, Tenthredinidae)

Prous, M.; Lee, K. M.; Mutanen, M.

10.1101/525626 — evolutionary biology — Posted on 2019-01-21

1241 Tissue nonspecific alkaline phosphatase improves bone quality but does not alleviate craniosynostosis in the FGFR2C342Y/+ mouse model of Crouzon syndrome

Nam, H. K.; Schutte, S. D.; Hatch, N.

10.1101/526400 — developmental biology — Posted on 2019-01-21

1242 Lipid rafts increase to facilitate ectoderm lineage specification of differentiating embryonic stem cells

Xu, C.; Cao, B.; Huo, Y.-d.; Niu, G.; Zhang, M. Q.; Mai, Z.-l.; Lu, X.-b.; Niu, H.-b.; Chen, D.-n.; Ni, Y.-x.

10.1101/520106 — cell biology — Posted on 2019-01-21

1243 Visual processing and attention rather than face and emotion processing play a distinct role in ASD: an EEG study

Khuntia, A. T.; Divakar, R.; Apicella, F.; Muratori, F.; Das, K.

10.1101/517664 — animal behavior and cognition — Posted on 2019-01-21

1244 Regionally diffuse muscle pain-hypersensitivity in humans during acute muscle pain

Dunn, J. S.; Nagi, S. S.; Mahns, D. A.

10.1101/525832 — neuroscience — Posted on 2019-01-21

1245 Longitudinal Trajectory of Early Functional Recovery in Patients with First Episode Psychosis

Hall, M.-H.; Holton, K. M.; Ongur, D.; Montrose, D.; Keshavan, M. S.

10.1101/525824 — neuroscience — Posted on 2019-01-21

1246 Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum.

Bevan-Jones, W. R.; Cope, T. E.; Jones, P. S.; Passamonti, L.; Hong, Y.; Fryer, T.; Arnold, R.; Coles, J.; Aigbirhio, F.; Larner, A.; Patterson, K.; O'Brien, J.; Rowe, J.

10.1101/525642 — neuroscience — Posted on 2019-01-21

1247 Caveolae and scaffold detection from single molecule localization microscopy data using deep learning

Khater, I. M.; Aroca-Ouellette, S. T.; Meng, F.; Nabi, I. R.; Hamarneh, G.

10.1101/526327 — molecular biology — Posted on 2019-01-21

1248 Expected Genotype Quality and Diploidized Marker Data from Genotyping-by-Sequencing of Urochloa spp. Tetraploids

Matias, F.; Meireles, K.; Nagamatsu, S.; Barrios, S.; do Valle, C.; Carazzolle, M.; Fritsche-Neto, R.; Endelman, J.

10.1101/525618 — genomics — Posted on 2019-01-21

1249 scSLAM-seq reveals core features of transcription dynamics in single cells

Erhard, F.; Baptista, M. A.; Krammer, T.; Hennig, T.; Lange, M.; Arampatzi, P.; Juerges, C.; Theis, F. J.; Saliba, A.-E.; Doelken, L.

10.1101/486852 — genomics — Posted on 2019-01-21

1250 Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacteria via Dynamic RNA Nanotechnology

Hanewich-Hollatz, M. H.; Chen, Z.; Huang, J.; Hochrein, L. M.; Pierce, N. A.

10.1101/525857 — synthetic biology — Posted on 2019-01-21

1251 Distribution and characterization of Aegilops cylindrica species from Iran

Bakhshi, B.; Jaffar Aghaei, M.; Zarifi, E.; Bihamta, M. R.; MohseniFard, E.

10.1101/525964 — plant biology — Posted on 2019-01-21

1252 Automated Pupillometry to Detect Command Following in Neurological Patients: A Proof-of-Concept Study

Vassilieva, A.; Olsen, M. H.; Peinkhofer, C.; Knudsen, G. M.; Kondziella, D.

10.1101/525212 — neuroscience — Posted on 2019-01-21

1253 Enabling MHC-mismatched hematopoietic stem cell transplants and organ graft tolerance without chemotherapy or radiation

George, B.; Kao, K. S.; Chen, A.; Le, A. C.; Chhabra, A.; Burnett, C.; Loh, K. M.; Shizuru, J. A.; Weissman, I.

10.1101/525899 — immunology — Posted on 2019-01-21

1254 Ends and middle: global force balance determines septum location in fission yeast

Le Goff, X.; Comelles, J.; Kervrann, C.; Riveline, D.

10.1101/520007 — cell biology — Posted on 2019-01-21

1255 Analysis of Risk Factor Domains in Psychosis Patient Health Records

Holderness, E.; Miller, N.; Cawkwell, P.; Bolton, K.; Pustejovsky, J.; Meteer, M.; Hall, M.-H.

10.1101/525816 — bioinformatics — Posted on 2019-01-21

1256 A variant of the student’s t-test for data of varying reliability

Sheth, S. B.; Sheth, B. R.

10.1101/525774 — bioinformatics — Posted on 2019-01-21

1257 Clustering and rapid long-range motility behavior of bacteria by type IV pili

Madukoma, C. S.; Morales-Soto, N.; Mattingly, A. E.; Lee, S. W.; Shrout, J. D.

10.1101/525790 — microbiology — Posted on 2019-01-21

1258 Differential effects of emerging broad-spectrum streetlight technologies on landscape-scale bat activity

Williams, R.; Walters, C.; Gibb, R.; Browning, E.; Tipping, D.; Jones, K.

10.1101/525568 — ecology — Posted on 2019-01-21

1259 Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2/3 islands located in euchromatic genome

Lee, Y. C. G.; Ogiyama, Y.; Martins, N. M. C.; Beliveau, B. J.; Acevedo, D.; Wu, C.- t.; Cavalli, G.; Karpen, G. H.

10.1101/525873 — genomics — Posted on 2019-01-21

1260 Simplified Molecular Classification of Lung Adenocarcinomas Based on EGFR, KRAS, and TP53 Mutations

Ruiz-Cordero, R.; Ma, J.; Khanna, A.; Lyons, G.; Rinsurongkawong, W.; Bassett, R.; Guo, M.; Routbort, M. J.; Zhang, J.; Sloulidis, F.; Heymach, J. V.; Roarty, E. B.; Tang, Z.; Medeiros, L. J.; Patel, K. P.; Luthra, R.; Roy-Chowdhuri, S.

10.1101/525949 — cancer biology — Posted on 2019-01-21

1261 Accurate detection of m6A RNA modifications in native RNA sequences

Liu, H.; Begik, O.; Lucas, M. C.; Mason, C. E.; Schwartz, S.; Mattick, J. S.; Smith, M. A.; Novoa, E. M.

10.1101/525741 — molecular biology — Posted on 2019-01-21

1262 Local inhibition of PRC2 activity by H3.3K27M drives DNA replication defects through misregulation of the JNK pathway

Delaney, K.; Strobino, M.; Wenda, J. M.; Pankowski, A.; Steiner, F. A.

10.1101/525766 — molecular biology — Posted on 2019-01-21

1263 p63 cooperates with CTCF to modulate chromatin architecture in skin keratinocytes

Qu, J.; Yi, G.; Zhou, J. H.

10.1101/525667 — genomics — Posted on 2019-01-21

1264 CTCF-mediated Chromatin Structures Dictate the Spatio-temporal Propagation of Replication Foci

Su, Q. P.; Zhao, Z. W.; Meng, L.; Ding, M.; Zhang, W.; Li, Y.; Liu, M.; Li, R.; Gao, Y.-Q.; Xie, X. S.; Sun, Y.

10.1101/525915 — cell biology — Posted on 2019-01-21

1265 A dynamic control of human telomerase holoenzyme

Sayed, M.; Cheng, A.; Yadav, G.; Ludlow, A.; Shay, J. W.; Wright, W. E.; Jiang, Q.-X.

10.1101/525733 — cell biology — Posted on 2019-01-21

1266 Alpha-Synuclein is a Target of Fic-mediated Adenylylation/AMPylation: Implications for Parkinson’s Disease

Mattoo, S.; Sanyal, A.; Dutta, S.; Chandran, A.; Koller, A.; Camara, A.; Watson, B. G.; Sengupta, R.; Ysselstein, D.; Montenegro, P.; Cannon, J. R.; Rochet, C.

10.1101/525659 — biochemistry — Posted on 2019-01-21

1267 Motion direction representation in multivariate electroencephalography activity for smooth pursuit eye movements

Lee, J.; Jeong, W.; Kim, S.; Kim, Y.-J.

10.1101/519074 — neuroscience — Posted on 2019-01-20

1268 Extensive splicing across the Saccharomyces cerevisiae genome

Douglass, S.; Leung, C. S.; Johnson, T. L.

10.1101/515163 — molecular biology — Posted on 2019-01-20

1269 Human DNA polymerase delta is a pentameric complex with dimeric p12 subunit: Implications in enzyme architecture and PCNA interaction

Khandagale, P.; Peroumal, D.; Manohar, K.; Acharya, N.

10.1101/525485 — biochemistry — Posted on 2019-01-20

1270 Cellular Dynamics and Genomic Identity of Centromeres in the Cereal Blast Fungus

Yadav, V.; Yang, F.; Reza, M. H.; Liu, S.; Valent, B.; Sanyal, K.; Naqvi, N. I.

10.1101/475574 — genetics — Posted on 2019-01-20

1271 Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors

Zhu, L.; Narloch, J. L.; Onkar, S.; Joy, M.; Luedke, C.; Hall, A.; Kim, R.; Pogue-Geile, K.; Sammons, S.; Nayyar, N.; Chukwueke, U.; Brastianos, P. K.; Anders, C. K.; Soloff, A. C.; Vignali, D. A.; Tseng, G.; Emens, L. A.; Lucas, P. C.; Blackwell, K. L.; Oesterreich, S.; Lee, A. V.

10.1101/525071 — immunology — Posted on 2019-01-20

1272 Distributed representations of protein domains and genomes and their compositionality

Viehweger, A.; Krautwurst, S.; Koenig, B.; Marz, M.

10.1101/524280 — genomics — Posted on 2019-01-20

1273 A genetic system for biasing the sex ratio in mice

Yosef, I.; Edry-Botzer, L.; Globus, R.; Shlomovitz, I.; Munitz, A.; Gerlic, M.; Qimron, U.

10.1101/515064 — developmental biology — Posted on 2019-01-20

1274 Frequency and power of human alpha oscillations drift systematically with time-on-task

Benwell, C. S.; London, R. E.; Tagliabue, C. F.; Veniero, D.; Gross, J.; Keitel, C.; Thut, G.

10.1101/263103 — neuroscience — Posted on 2019-01-20

1275 Single-cell RNA-seq identifies a reversible epithelial-mesenchymal transition in abnormally specified epithelia of p63 EEC syndrome

Soares, E.; Xu, Q.; Li, Q.; Qu, J.; Zheng, Y.; Raeven, H. H. M.; Brandao, K.; Petit, I.; van den Akker, W. M. R.; Aberdam, D.; Tang, F.; Zhou, H.

10.1101/437632 — developmental biology — Posted on 2019-01-20

1276 StormGraph: An automated graph-based algorithm for quantitative clustering analysis of single-molecule localization microscopy data

Scurll, J.; Abraham, L.; Zheng, D. W.; Tafteh, R.; Chou, K.; Gold, M. R.; Coombs, D.

10.1101/515627 — biophysics — Posted on 2019-01-20

1277 Distinct role of flexible and stable encoding in sequential working memory

Lee, H.; Choi, W.; Park, Y.; Paik, S.-B.

10.1101/525220 — neuroscience — Posted on 2019-01-20

1278 A role for ATP Citrate Lyase in cell cycle regulation during myeloid differentiation

Rhee, J.; Solomon, L. A.; DeKoter, R. P.

10.1101/525303 — immunology — Posted on 2019-01-20

1279 Genome-wide association study, replication, and mega-analysis using a dense marker panel in a multi-generational mouse advanced intercross line

Zhou, X.; St. Pierre, C. L.; Gonzales, N. M.; Cheng, R.; Chitre, A. S.; Sokoloff, G.; Palmer, A. A.

10.1101/387613 — genetics — Posted on 2019-01-20

1280 Vocal Transmission of Breeding Status May Facilitate Dispersal in a Cooperative Breeding Primate

Robakis, E.; Erkenswick, G.; Watsa, M.

10.1101/525121 — animal behavior and cognition — Posted on 2019-01-20

1281 The transferability of lipid-associated loci across African, Asian and European cohorts

Telkar, N.; Reiker, T.; Walters, R. G.; Lin, K.; Gurdasani, D.; Gilly, A.; Southam, L.; Tsafantakis, E.; Karaleftheri, M.; Seeley, J.; Kamali, A.; Asiki, G.; Millwood, I. Y.; Du, H.; Guo, Y.; Understanding Society Scientific Group, ; Kumari, M.; Dedoussis, G.; Li, L.; Chen, Z.; Sandhu, M.; Zeggini, E.; Kuchenbaecker, K.

10.1101/525170 — genetics — Posted on 2019-01-20

1282 Positively twisted: The complex evolutionary history of Reverse Gyrase suggests a non-hyperthermophilic Last Universal Common Ancestor

Catchpole, R.; Forterre, P.

10.1101/524215 — evolutionary biology — Posted on 2019-01-20

1283 A review of the relation between species traits and extinction risk

Chichorro, F.; Juslen, A.; Cardoso, P.

10.1101/408096 — ecology — Posted on 2019-01-20

1284 The large loop-8 insert in Saccharomyces cerevisiae kinesin-5 Cin8 is necessary and sufficient to promote noncanonical microtubule interactions

Bell, K. M.; Cochran, J. C.

10.1101/525329 — biochemistry — Posted on 2019-01-20

1285 Population coupling predicts the plasticity of stimulus responses in cortical circuits

Sweeney, Y.; Clopath, C.

10.1101/265041 — neuroscience — Posted on 2019-01-20

1286 Moraxellaceae and Moraxella interact with the altered airway mycobiome in asthma

Liu, H.; Li, C.; Liang, Z.; Zhang, S.; Yang, W.; Ye, Y.; Lin, Y.; Chen, R.; Zhou, H.-W.; Su, J.

10.1101/525113 — microbiology — Posted on 2019-01-20

1287 A catalog of single nucleotide changes distinguishing modern humans from archaic hominins

Kuhlwilm, M.; Boeckx, C.

10.1101/298950 — evolutionary biology — Posted on 2019-01-20

1288 The statistics of noisy growth with mechanical feedback in elastic tissues

Khatib Damavandi, O.; Lubensky, D. K.

10.1101/426361 — biophysics — Posted on 2019-01-20

1289 Waterborne, abiotic and other indirectly transmitted (W.A.I.T.) infections are defined by the dynamics of free-living pathogens and environmental reservoirs

Miller-Dickson, M.; Meszaros, V. A.; Baffour-Awuah Junior, F.; Almagro-Moreno, S.; Ogbunugafor, C. B.

10.1101/525089 — systems biology — Posted on 2019-01-20

1290 Modular structure of human olfactory receptor codes reflects the bases of odor perception

Bak, J. H.; Jang, S.; Hyeon, C.

10.1101/525287 — neuroscience — Posted on 2019-01-20

1291 Validity and internal consistency of EQ-5D-3L quality of life tool among pre-dialysis patients with chronic kidney disease in Sri Lanka, a lower middle-income country

Senanayake, S.; Mahesh, P.; Gunawardena, N.; Graves, N.; Kularatna, S.

10.1101/524603 — epidemiology — Posted on 2019-01-20

1292 DISPOT: A simple knowledge-based protein domain interaction statistical potential

Narykov, O.; Korkin, D.

10.1101/525535 — bioinformatics — Posted on 2019-01-20

1293 Human DNA polymerase delta is a pentameric complex with dimeric p12 subunit: Implications in enzyme architecture and PCNA interaction

Khandagale, P.; Peroumal, D.; Manohar, K.; Acharya, N.

10.1101/525485 — molecular biology — Posted on 2019-01-20

1294 Role of Era in Assembly and Homeostasis of the Ribosomal Small Subunit

Razi, A.; Davis, J. H.; Hao, Y.; Jahagirdar, D.; Thurlow, B.; Basu, K.; Jain, N.; Gomez-Blanco, J.; Britton, R. A.; Vargas, J.; Guarne, A.; Woodson, S.; Williamson, J.; Ortega, J.

10.1101/525360 — molecular biology — Posted on 2019-01-20

1295 Genomewide Analyses of Psychological Resilience in US Army Soldiers

Stein, M.; Choi, K. W.; Jain, S.; Campbell-Sills, L.; Chen, C.-Y.; Gelernter, J.; He, F.; Heeringa, S. G.; Maihofer, A. X.; Nievergelt, C. M.; Nock, M. K.; Ripke, S.; Sun, X.; Kessler, R. C.; Smoller, J. W.; Ursano, R. J.

10.1101/516716 — genetics — Posted on 2019-01-20

1296 Multiple selection signatures in farmed Atlantic salmon adapted to different environments across Hemispheres

Lopez, M.-E.; Linderoth, T.; Norris, A.; Lhorente, J.-P.; Neira, R.; Yanez, J. M.

10.1101/525550 — genetics — Posted on 2019-01-20

1297 Neither global nor consistent: a technical comment on the tree diversity-productivity analysis of Liang et al. (2016)

Dormann, C. F.; Schneider, H.; Gorges, J.

10.1101/524363 — ecology — Posted on 2019-01-20

1298 ya||a: GPU-powered Spheroid Models for Mesenchyme and Epithelium

Germann, P.; Marin-Riera, M.; Sharpe, J.

10.1101/525352 — systems biology — Posted on 2019-01-20

1299 In vitro implementation of robust gene regulation in a synthetic biomolecular integral controller

Agrawal, D. K.; Marshall, R.; Noireaux, V.; Sontag, E. D.

10.1101/525279 — synthetic biology — Posted on 2019-01-20

1300 Feeling left out or just surprised? Neural correlates of social exclusion and expectancy violations in adolescence

Cheng, T.; Vijayakumar, N.; Flournoy, J. C.; Op de Macks, Z.; Peake, S. J.; Flannery, J. E.; Mobasser, A.; Alberti, S. L.; Fisher, P. A.; Pfeifer, J. H.

10.1101/524934 — neuroscience — Posted on 2019-01-20

1301 Tandem Directional CTCF Sites Balance Protocadherin Promoter Usage

Wu, Q.; Guo, Y.; Lu, Y.; Li, J.; Wu, Y.; Jia, Z.

10.1101/525543 — molecular biology — Posted on 2019-01-20

1302 A genome-wide association study identifies that the GDF5 and COL27A1 genes are associated with knee pain in UK Biobank (N = 171, 516)

Meng, W.; Adams, M.; Palmer, C.; Shi, J.; Auton, A.; Ryan, K.; Jordan, J.; Mitchell, B.; Jackson, R.; Yau, M.; McIntosh, A. M.; Smith, B.

10.1101/525147 — genetics — Posted on 2019-01-20

1303 Interdependent photo- and chemosensory systems regulate larval settlement in a marine sponge

Say, T. E.; Degnan, S. M.

10.1101/519512 — developmental biology — Posted on 2019-01-20

1304 Identifying Genomic Islands with Deep Neural Networks

Assaf, R.; Xia, F.; Stevens, R.

10.1101/525030 — bioinformatics — Posted on 2019-01-20

1305 Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis

Riley, N. M.; Hebert, A. S.; Westphall, M. S.; Coon, J. J.

10.1101/524983 — systems biology — Posted on 2019-01-20

1306 Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven AAVs

10.1101/525014 — neuroscience — Posted on 2019-01-20

1307 Multimodal cell type correspondence by intersectional mFISH in intact tissues

10.1101/525451 — neuroscience — Posted on 2019-01-20

1308 A curated collection of transcriptome datasets to investigate the molecular mechanisms of immunoglobulin E-mediated atopic diseases

Huang, S.; Al Ali, F.; Boughorbel, S.; Toufiq, M.; Chaussabel, D.; Garand, M.

10.1101/525477 — immunology — Posted on 2019-01-20

1309 Fast and robust method for drug response biomarker identification and sample stratification.

Das, A.; Bhattacharya, S.

10.1101/525337 — bioinformatics — Posted on 2019-01-20

1310 Fast estimation of genetic correlation for Biobank-scale data

Wu, Y.; Yaschenko, A.; Heydary, M. H.; Sankararaman, S.

10.1101/525055 — bioinformatics — Posted on 2019-01-20

1311 Isoniazid resistance in Mycobacterium tuberculosis is a heterogeneous phenotype comprised of overlapping MIC distributions with different underlying resistance mechanisms

Ghodousi, A.; Tagliani, E.; Karunaratne, E.; Niemann, S.; Perera, J.; Köser, C. U.; Cirillo, D. M.

10.1101/524157 — microbiology — Posted on 2019-01-20

1312 AGO1 in association with NEAT1 lncRNA contributes to nuclear and 3D chromatin architecture in human cells

Shuaib, M.; Parsi, K. M.; Kawaji, H.; Thimma, M.; Adroub, S. A.; Fort, A.; Ghosheh, Y.; Yamazaki, T.; Mannen, T.; Seridi, L.; Fallatah, B.; Albawardi, W.; Ravasi, T.; Carninci, P.; Hirose, T.; Orlando, V.

10.1101/525527 — genomics — Posted on 2019-01-20

1313 Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

Lam, M.; Hill, W. D.; Trampush, J. W.; Yu, J.; Knowles, E.; Davies, G.; Stahl, E.; Huckins, L.; Liewald, D. C.; Djurovic, S.; Melle, I.; Sundet, K.; Christoforou, A.; Reinvang, I.; DeRosse, P.; Lundervold, A.; Steen, V. M.; Espeseth, T.; Raikkonen, K.; Widen, E.; Palotie, A.; Eriksson, J. G.; Giegling, I.; Konte, B.; Hartmann, A. M.; Roussos, P.; Giakoumaki, S.; Burdick, K. E.; Payton, A.; Ollier, W.; Chiba-Falek, O.; Attix, D. K.; Need, A. C.; Cirulli, E. T.; Voineskos, A. N.; Stefanis, N.; Avramopoulos, D.; Hatzimanolis, A.; Arking, D. E.; Smyrnis, N.; Bilder, R. M.; Freimer, N. A.; Cannon,

10.1101/519967 — genetics — Posted on 2019-01-20

1314 Skull base meningiomas have a distinct immune landscape.

Zador, Z.; Landry, A.; Balas, M.; Cusimano, M.

10.1101/525444 — cancer biology — Posted on 2019-01-20

1315 De Novo Peptide Sequencing Reveals a Vast Cyclopeptidome in Human Gut and Other Environments

Behsaz, B.; Mohimani, H.; Gurevich, A.; Prjibelski, A.; Fisher, M. F.; Smarr, L.; Dorrestein, P. C.; Mylne, J. S.; Pevzner, P. A.

10.1101/521872 — bioinformatics — Posted on 2019-01-20

1316 De novo assembly of the Mongolian gerbil genome and transcriptome

Cheng, S.; Fu, Y.; Zhang, Y.; Xian, W.; Wang, H.; Grothe, B.; Lu, X.; Xu, X.; Klug, A.; McCullagh, E. A.

10.1101/522516 — genomics — Posted on 2019-01-19

1317 Why panmictic bacteria are rare

Yang, C.; Cui, Y.; Didelot, X.; Yang, R.; Falush, D.

10.1101/385336 — microbiology — Posted on 2019-01-19

1318 Comparison of HSV-1 strains circulating in Finland demonstrates the uncoupling of whole-genome relatedness and phenotypic outcomes of viral infection

Bowen, C. D.; Paavilainen, H.; Renner, D. W.; Palomäki, J.; Lehtinen, J.; Vuorinen, T.; Norberg, P.; Hukkanen, V.; Szpara, M.

10.1101/424408 — microbiology — Posted on 2019-01-19

1319 The antimicrobial peptide Defensin cooperates with Tumour Necrosis Factor to drive tumour cell death in Drosophila

Parvy, J.-P.; Yu, Y.; Dostalova, A.; Kondo, S.; Kurjan, A.; Bulet, P.; Lemaitre, B.; Vidal, M.; Cordero, J.

10.1101/513747 — cancer biology — Posted on 2019-01-19

1320 Structural Insights into GluK3-kainate Receptor Desensitization and Recovery

Kumari, J.; Vinnakota, R.; Kumar, J.

10.1101/525154 — biochemistry — Posted on 2019-01-19

1321 The landscape of coadaptation in Vibrio parahaemolyticus

Cui, Y.; Yang, C.; Qiu, H.; Wang, H.; Yang, R.; Falush, D.

10.1101/373936 — microbiology — Posted on 2019-01-19

1322 Recent mixing of Vibrio parahaemolyticus populations

Yang, C.; Pei, X.; Wu, Y.; Yan, L.; Yan, Y.; Song, Y.; Coyle, N.; Martinez-Urtaza, J.; Quince, C.; Hu, Q.; Jiang, M.; Feil, E.; Yang, D.; Song, Y.; Zhou, D.; Yang, R.; Falush, D.; Cui, Y.

10.1101/354761 — microbiology — Posted on 2019-01-19

1323 Exaggerated in vivo IL-17 responses discriminate recall responses in active TB

Pollara, G.; Turner, C. T.; Tomlinson, G. S.; Bell, L. C.; Khan, A.; Peralta, L. F.; Folino, A.; Akarca, A.; Venturini, C.; Baker, T.; Ricciardolo, F. L.; Marafioti, T.; Ugarte-Gil, C.; Moore, D. A.; Chain, B. M.; Noursadeghi, M.

10.1101/516690 — immunology — Posted on 2019-01-19

1324 Implementation of an antibody characterization process: Application to the major ALS/FTD disease gene C9ORF72

Laflamme, C.; McKeever, P.; Kumar, R.; Schwartz, J.; Chen, C. X.- Q.; You, Z.; Xiao, S.; Benaliouad, F.; Gileadi, O.; McBride, H. M.; Durcan, T. M.; Edwards, A.; Robertson, J.; McPherson, P.

10.1101/499350 — molecular biology — Posted on 2019-01-19

1325 Mechanisms of a locally adaptive shift in allocation among growth, reproduction, and herbivore resistance in Mimulus guttatus

Lowry, D.; Popovic, D.; Brennan, D. J.; Holeski, L. M.

10.1101/400523 — evolutionary biology — Posted on 2019-01-19

1326 Non-proliferative adult neurogenesis in neural crest-derived stem cells isolated from human periodontal ligament.

Bueno, C.; Martinez-Morga, M.; Martinez, S.

10.1101/325613 — neuroscience — Posted on 2019-01-19

1327 GHOST: Recovering Historical Signal from Heterotachously-evolved Sequence Alignments

Crotty, S. M.; Minh, B. Q.; Bean, N. G.; Holland, B. R.; Tuke, J.; Jermiin, L. S.; von Haeseler, A.

10.1101/174789 — evolutionary biology — Posted on 2019-01-19

1328 sFlt-1 commutes unfolded protein response into endoplasmic reticulum stress in trophoblast cells in preeclamptic pregnancies

Mochan, S.; Dhingra, M. K.; Gupta, S. K.; Saxena, S.; Arora, P.; Rani, N.; Sharma, A.; Luthra, K.; Dwivedi, S. N.; Bhatla, N.; Kumar, R.; Dhingra, R.

10.1101/297374 — developmental biology — Posted on 2019-01-19

1329 Cortical tethering of mitochondria by the dynein anchor Mcp5 enables uniparental mitochondrial inheritance during fission yeast meiosis

Mehta, K.; Ananthanarayanan, V.

10.1101/525196 — cell biology — Posted on 2019-01-19

1330 In-field metagenome and 16S rRNA gene amplicon nanopore sequencing robustly characterize glacier microbiota

Edwards, A.; Debbonaire, A. R.; Nicholls, S. M.; Rassner, S. M.; Sattler, B.; Cook, J. M.; Davy, T.; Soares, A. R.; Mur, L. A.; Hodson, A. J.

10.1101/073965 — microbiology — Posted on 2019-01-19

1331 Chaperone-mediated ordered assembly of the SAGA transcription complex

Elias-Villalobos, A.; Toullec, D.; Faux, C.; Lledo, G.; Seveno, M.; Helmlinger, D.

10.1101/524959 — biochemistry — Posted on 2019-01-19

1332 Combinatorial Treatment Increases IKAP Levels in Human Cells Generated from Familial Dysautonomia Patients

Ast, G.; Yanai, S.; Zonszain, J.; Donyo, M.

10.1101/524587 — molecular biology — Posted on 2019-01-19

1333 A Simple Cross-Linking/Mass Spectrometry Workflow to Study System-Wide Protein Interactions

Goetze, M.; Iacobucci, C.; Ihling, C.; Sinz, A.

10.1101/524314 — molecular biology — Posted on 2019-01-19

1334 China’s Development Assistance for Health on Key Tropical Diseases: A SWOT Analysis

Li, H.-M.; Ding, W.; Huang, L.-L.; Ma, X.; Qian, Y.-J.; Wang, D.-Q.; Xiao, N.; Guan, Y.-Y.; Zhou, X.-N.

10.1101/524678 — epidemiology — Posted on 2019-01-19

1335 Transcriptome analysis of the Molecular Mechanism underlying Immunity- and Reproduction trade-off in Locusta migratoria Infected by Micrococcus luteus

Wang, S.; Wang, S.; Liu, X.; Xia, Z.; Xie, G.; Tang, B.

10.1101/524611 — animal behavior and cognition — Posted on 2019-01-19

1336 In vivo structure of the Legionella type II secretion system by electron cryotomography

Ghosal, D.; Kim, K. W.; Zheng, H.; Kaplan, M.; Vogel, J. P.; Cianciotto, N. P.; Jensen, G. J.

10.1101/525063 — microbiology — Posted on 2019-01-19

1337 The KZFP/KAP1 system controls transposable elements-embedded regulatory sequences in adult T cells

Trono, D.; Marzetta, F.; Simo-Riudalbas, L.; Duc, J.; Planet, E.; Verp, S.; Turelli, P.

10.1101/523597 — genomics — Posted on 2019-01-19

1338 Survival Analysis and Prognostic Factors of Time to First Domestic Violence after Marriage among Married Women in Africa

Fagbamigbe, A. F.; AKINTAYO, A. O.; OSHODI, O. C.; MAKINDE, F. T.; BABALOLA, M.; ARAOYE, D.; ENABOR, C.

10.1101/524637 — epidemiology — Posted on 2019-01-19

1339 Direct binding of the flexible C-terminal segment of periaxin to β4 integrin suggests a molecular basis for CMT4F

Raasakka, A.; Linxweiler, H.; Brophy, P. J.; Sherman, D. L.; Kursula, P.

10.1101/524793 — neuroscience — Posted on 2019-01-19

1340 Mutations close to the peptidoglycan-binding region of the stators of the bacterial flagellar motor influence phenamil resistance

Ishida, T.; Ito, R.; Clark, J.; Matzke, N. J.; Sowa, Y.; Baker, M. A.

10.1101/507533 — microbiology — Posted on 2019-01-19

1341 Understanding the variation in wood densities of trees and its implications for carbon assessments

Teegalapalli, K.; Pandey, C. K.; Osuri, A.; Ratnam, J.; Sankaran, M.

10.1101/523480 — ecology — Posted on 2019-01-19

1342 A large-scale multivariate pQTL study sheds light on the genetic architecture of obesity

Ruffieux, H.; Carayol, J.; Harper, M. E.; Dent, R.; Saris, W.; Astrup, A.; Davison, A.; Hager, J.; Valsesia, A.

10.1101/524405 — genetics — Posted on 2019-01-18

1343 Risks to pollinators from different land-use transitions: bee species’ responses to agricultural expansion show strong phylogenetic signal

De Palma, A.; Kuhlmann, M.; Pearse, W. D.; Flynn, E.; Roberts, S. P. M.; Potts, S. G.; Purvis, A.

10.1101/524546 — ecology — Posted on 2019-01-18

1344 Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr-/- mice

Tao, H.; Huang, J.; Yancey, P. G.; Ding, L.; Zhang, Y.; Blakemore, J. L.; Amarnath, V.; Oates, J. A.; Roberts, L. J.; Davies, S. S.; Linton, M. F.

10.1101/524884 — pharmacology and toxicology — Posted on 2019-01-18

1345 Direct binding of the flexible C-terminal segment of periaxin to β4 integrin suggests a molecular basis for CMT4F

Raasakka, A.; Linxweiler, H.; Brophy, P. J.; Sherman, D. L.; Kursula, P.

10.1101/524793 — neuroscience — Posted on 2019-01-18

1346 Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression

Sasse, S. K.; Gruca, M.; Allen, M. A.; Kadiyala, V.; Song, T.; Gally, F.; Gupta, A.; Pufall, M. A.; Dowell, R. D.; Gerber, A. N.

10.1101/524975 — molecular biology — Posted on 2019-01-18

1347 Sequence based mapping identifies AWNS1, a candidate transcription repressor underlying awn suppression at the B1 locus in wheat

DeWitt, N.; Guedira, M.; Lauer, E.; Sarinelli, M.; Tyagi, P.; Hao, Q.; Fu, D.; Murphy, J. P.; Marshall, D.; Akhunova, A.; Jordan, K.; Akhunov, E.; Brown-Guedira, G.

10.1101/519264 — genetics — Posted on 2019-01-18

1348 Accounting for imperfect detection in species with sessile life cycle stages: a case study of bumble bee colonies

Iles, D.; Pugesek, G.; Kerr, N. Z.; Dorian, N. N.; Crone, E. E.

10.1101/518407 — ecology — Posted on 2019-01-18

1349 Characterization of the interactive effects of labile and recalcitrant organic matter on microbial growth and metabolism

Quigley, L. N. M.; Edwards, A.; Steen, A. D.; Buchan, A.

10.1101/524777 — microbiology — Posted on 2019-01-18

1350 Accuracy of gene expression prediction from genotype data with PrediXcan varies across diverse populations

Mikhaylova, A. V.; Thornton, T. A.

10.1101/524728 — genomics — Posted on 2019-01-18

1351 Deep phenotyping of a healthy human HAO1 knockout informs therapeutic development for primary hyperoxaluria type 1.

McGregor, T. L.; Hunt, K. A.; Nioi, P.; Mason, D.; Ticau, S.; Pelosi, M.; Perry, L.; Finer, S.; Griffiths, C.; MacArthur, D.; Trembath, R. C.; Oglesbee, D.; Lieske, J.; Wright, J.; Erbe, D.; van Heel, D.

10.1101/524256 — genetics — Posted on 2019-01-18

1352 Isogenic human iPSC pairs reveal a neuronal subtype-specific and genetic background-independent mechanism of SCN1A epilepsy

Xie, Y.; Ng, N. N.; Safrina, O. S.; Ramos, C. M.; Ess, K. C.; Schwartz, P. H.; Smith, M. A.; O'Dowd, D. K.

10.1101/524835 — neuroscience — Posted on 2019-01-18

1353 Domain-specific working memory, but not dopamine-related genetic variability, shapes reward-based motor learning

Codol, O.; Holland, P. J.; Oxley, E.; Taylor, M.; Hamshere, E.; Joseph, S.; Huffer, L.; Galea, J. M.

10.1101/524900 — neuroscience — Posted on 2019-01-18

1354 Global and regional white matter development in early childhood

Reynolds, J. E.; Grohs, M. N.; Dewey, D.; Lebel, C.

10.1101/524785 — neuroscience — Posted on 2019-01-18

1355 Nanoscopic Stoichiometry and Single-Molecule Counting

Nino, D.; Djayakarsana, D.; Milstein, J. N.

10.1101/524801 — biophysics — Posted on 2019-01-18

1356 Effects of Standing on Spinal Alignment and Lumbar Intervertebral Discs in Young, Healthy Individuals Determined by Positional Magnetic Resonance Imaging

Weber, C. I.; Hwang, C.-T.; Van Dillen, L. R.; Tang, S. Y.

10.1101/522565 — physiology — Posted on 2019-01-18

1357 Transcriptomic correlates of electrophysiological and morphological diversity within and across neuron types

Bomkamp, C.; Tripathy, S.; Bengtsson Gonzales, C.; Hjerling Leffler, J.; Craig, A. M.; Pavlidis, P.

10.1101/524561 — neuroscience — Posted on 2019-01-18

1358 Individual differences in the effects of priors on perception: a multi-paradigm approach

Tulver, K.; Aru, J.; Rutiku, R.; Bachmann, T.

10.1101/523324 — neuroscience — Posted on 2019-01-18

1359 Landscape-scale simulations as a tool in multi-criteria decision making for agri-environment schemes

Topping, C.; Dalby, L.; Valdez, J.

10.1101/524181 — ecology — Posted on 2019-01-18

1360 Reproducibility of functional brain alterations in major depressive disorder: evidence from a multisite resting-state functional MRI study with 1,434 individuals

Xia, M.; Si, T.; Sun, X.; Ma, Q.; Liu, B.; Wang, L.; Meng, J.; Chang, M.; Huang, X.; Chen, Z.; Tang, Y.; Xu, K.; Gong, Q.; Wang, F.; Qiu, J.; Xie, P.; Li, L.; He, Y.; DIDA-Major Depressive Disorder Working Group,

10.1101/524496 — neuroscience — Posted on 2019-01-18

1361 Investigating causal pathways between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.

Treur, J.; Demontis, D.; Sallis, H.; ADHD working group of the Psychiatric Genomics Consortium, ; Richardson, T.; Wiers, R.; Borglum, A.; Verweij, K.; Munafo, M.

10.1101/524769 — genetics — Posted on 2019-01-18

1362 Comparative analyses of chromatin landscape in white adipose tissue suggest humans may have less beigeing potential than other primates

Swain Lenz, D. S.; Berrio, A.; Saffi, A.; Crawford, G. E.; Wray, G.

10.1101/524868 — evolutionary biology — Posted on 2019-01-18

1363 Widespread selection for high and low secondary structure in coding sequences across all domains of life

Gebert, D.; Jehn, J.; Rosenkranz, D.

10.1101/524538 — evolutionary biology — Posted on 2019-01-18

1364 Cysteine modification can gate non-equilibrium conformational dynamics during enzyme catalysis

DasGupta, M.; Budday, D.; Madzelan, P.; Seravalli, J.; Hayes, B.; Sierra, R. G.; Alonso-Mori, R.; Brewster, A. S.; Sauter, N. K.; Applegate, G. A.; Tiwari, V.; Berkowitz, D. B.; Thompson, M. C.; Fraser, J. S.; Wall, M. E.; van den Bedem, H.; Wilson, M. A.

10.1101/524751 — biochemistry — Posted on 2019-01-18

1365 Ontological Dimensions of Cognitive-Neural Mappings

Bolt, T.; Nomi, J. S.; Arens, R.; Vij, S. G.; Riedel, M.; Salo, T.; Laird, A. R.; Eickhoff, S. B.; Uddin, L. Q.

10.1101/524520 — neuroscience — Posted on 2019-01-18

1366 The reconstitution of body mass index in HIV positive subjects under antiretroviral treatment in Kinshasa

Tshima, G. K.

10.1101/524462 — microbiology — Posted on 2019-01-18

1367 Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements

Tycko, J.; Wainberg, M.; Marinov, G. K.; Ursu, O.; Hess, G. T.; Ego, B. K.; Aradhana, ; Li, A.; Truong, A.; Trevino, A. E.; Spees, K.; Yao, D.; Kaplow, I. M.; Greenside, P. G.; Morgens, D. W.; Phanstiel, D. H.; Snyder, M. P.; Bintu, L.; Greenleaf, W. J.; Kundaje, A.; Bassik, M. C.

10.1101/520569 — genomics — Posted on 2019-01-18

1368 The landscape of SNCA transcripts across synucleinopathies: New insights from long reads sequencing analysis

Tseng, E.; Rowell, W. J.; Omolara-Chinue, G.; Hon, T.; Barrera, J.; Kujawa, S.; Chiba-Falek, O.

10.1101/524827 — genetics — Posted on 2019-01-18

1369 Rapidly processed stool swabs approximate stool microbiota profiles

Bokulich, N. A.; Maldonado, J.; Kang, D.; Krajmalnik-Brown, R.; Caporaso, J. G.

10.1101/524512 — microbiology — Posted on 2019-01-18

Mukaremera, L.; McDonald, T. R.; Nielsen, J. N.; Akampulira, A.; Schutz, C.; Tazeera, K.; Muzoora, C.; Meintjes, G. A.; Meya, D. B.; Boulware, D.; Nielsen, K.

10.1101/524165 — microbiology — Posted on 2019-01-18

1371 Comprehensive analysis of RNA-seq kits for standard, low and ultra-low quantity samples

Palomares, M.-A.; Dalmasso, C.; Bonnet, E.; Derbois, C.; Brohard-Julien, S.; Ambroise, C.; Battail, C.; Deleuze, J.-F.; Olaso, R.

10.1101/524439 — genomics — Posted on 2019-01-18

1372 Genetic Nature or Genetic Nurture? Quantifying Bias in Analyses Using Polygenic Scores

Trejo, S.; Domingue, B. W.

10.1101/524850 — genomics — Posted on 2019-01-18

1373 Eco-Evolutionary Feedbacks Between Predator’s Linkage Disequilibrium and Prey Densities Maintain Diversity

Patel, S.; Buerger, R.

10.1101/523720 — evolutionary biology — Posted on 2019-01-18

1374 The evolution of collective infectious units in viruses

Leeks, A.; Sanjuan, R.; West, S. A.

10.1101/524694 — evolutionary biology — Posted on 2019-01-18

1375 Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Regnier, M.; Polizzi, A.; Smati, S.; Lukowicz, C.; Fougerat, A.; Lippi, Y.; Fouche, E.; Lasserre, F.; Naylies, C.; Betoulieres, C.; Barquissau, V.; Mouisel, E.; Bertrand-Michel, J.; Batut, A.; Al Saati, T.; Canlet, C.; Tremblay-Franco, M.; Ellero-Simatos, S.; Langin, D.; Postic, C.; Wahli, W.; Loiseau, N.; Guillou, H.; Montagner, A.

10.1101/488031 — pathology — Posted on 2019-01-18

1376 Border-ownership-dependent tilt aftereffect for shape defined by binocular disparity and motion parallax

Rideaux, R.; Harrison, W.

10.1101/472076 — neuroscience — Posted on 2019-01-18

1377 Reconstruction of Par polarity in apolar cells reveals a dynamic process of cortical polarization

Kono, K.; Yoshiura, S.; Fujita, I.; Okada, Y.; Shitamukai, A.; Shibata, T.; Matsuzaki, F.

10.1101/523589 — cell biology — Posted on 2019-01-18

1378 Does testosterone impair men’s cognitive empathy? Evidence from two large-scale randomized controlled trials

Nadler, A.; Zava, D.; Ortiz, T.; Watson, N.; Carre, J.; Camerer, C.; Nave, G.

10.1101/516344 — neuroscience — Posted on 2019-01-18

1379 A brainstem-central amygdala circuit underlies defensive responses to learned threats

Gu, Y.; Vazey, E. M.; Aston-Jones, G.; Lin, L.; LeDoux, J. E.; Sears, R. M.

10.1101/519249 — neuroscience — Posted on 2019-01-18

1380 Non-apoptotic pioneer neutrophils initiate an endogenous swarming response in a zebrafish tissue injury model

Isles, H. M.; Muir, C. F.; Hamilton, N.; Kadochnikova, A.; Loynes, C. A.; Kadirkamanathan, V.; Elks, P. M.; Renshaw, S. A.

10.1101/521450 — immunology — Posted on 2019-01-18

1381 Scarless Enriched selection of Genome edited Human Pluripotent Stem Cells Using Induced Drug Resistance

Kim, K.-T.; Park, J.-C.; Lee, H.; Jang, H.-K.; Jin, Y.; Kim, W.; Lee, J.; Kim, H. H.; Bae, S.; Cha, H.-J.

10.1101/522383 — genetics — Posted on 2019-01-18

1382 Phylogenetic Clustering by Linear Integer Programming (PhyCLIP)

Han, A. X.; Parker, E.; Scholer, F.; Maurer-Stroh, S.; Russell, C. A.

10.1101/446716 — bioinformatics — Posted on 2019-01-18

1383 Spatial control of oxygen delivery to 3D cultures alters cancer cell growth and gene expression

Wulftange, W. J.; Rose, M. A.; Garmendia-Cedillos, M.; da Silva, D.; Poprawski, J. E.; Srinivasachar, D.; Sullivan, T.; Lim, L.; Bliskovsky, V. V.; Hall, M. D.; Pohida, T. J.; Robey, R. W.; Morgan, N. Y.; Gottesman, M. M.

10.1101/522656 — bioengineering — Posted on 2019-01-18

1384 Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspired Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents

Perov, S.; Lidor, O.; Salinas, N.; Golan, N.; Tayeb-Fligelman, E.; Deshmukh, M.; Willbold, D.; Landau, M.

10.1101/493668 — biochemistry — Posted on 2019-01-18

1385 Computational Intractability Law Molds the Topology of Biological Networks

Atiia, A. A.; Hopper, C.; Inoue, K.; Vidal, S.; Waldispuhl, J.

10.1101/510495 — systems biology — Posted on 2019-01-18

1386 Miltefosine increases macrophage cholesterol efflux and inhibits NLRP3-inflammasome assembly and IL-1beta release.

Iacano, A. J.; Lewis, H.; Hazen, J. E.; Andro, H.; Smith, J. D.; Gulshan, K.

10.1101/430769 — cell biology — Posted on 2019-01-18

1387 Transcriptome landscape of a thermal-tolerant coral endosymbiont reveals molecular signatures of symbiosis and dysbiosis

Bellantuono, A. J.; Dougan, K. E.; Granados-Cifuentes, C.; Rodriguez-Lanetty, M.

10.1101/508184 — genomics — Posted on 2019-01-18

1388 Statistically consistent divide-and-conquer pipelines for phylogeny estimation using NJMerge

Molloy, E. K.; Warnow, T.

10.1101/469130 — evolutionary biology — Posted on 2019-01-18

1389 Dominant coral bacterium Endozoicomonas acroporae metabolizes DMSP

Tandon, K.; Chiang, P.-W.; Lu, C.-Y.; Yang, S.-H.; Chan, Y.-F.; Wada, N.; Chen, P.-Y.; Chang, H.-Y.; Chou, M.-S.; Chen, W.-M.; Tang, S.-L.

10.1101/519546 — ecology — Posted on 2019-01-18

1390 PhyloPi: an affordable, purpose built phylogenetic pipeline for the HIV drug resistance testing facility

Bester, P. A.; De Vries, A.; Riekert, S. J.; Steegen, K.; van Zyl, G.; Goedhals, D.

10.1101/367946 — bioinformatics — Posted on 2019-01-18

1391 The Landscape of Parkin Variants Reveals Pathogenic Mechanisms and Therapeutic Targets in Parkinson’s Disease

Yi, W.; MacDougall, E. J.; Tang, M.; Roldan, A. K.; Gan-Or, Z.; Trempe, J.-F.; Fon, E. A.

10.1101/445551 — neuroscience — Posted on 2019-01-18

1392 The effects on neutral variability of recurrent selective sweeps and background selection

Campos Parada, J. L.; Charlesworth, B.

10.1101/358309 — evolutionary biology — Posted on 2019-01-18

1393 Increased frequency of travel in the presence of cross-immunity may act to decrease the chance of a global pandemic

Thompson, R.; Thompson, C.; Pelerman, O.; Gupta, S.; Obolski, U.

10.1101/404871 — epidemiology — Posted on 2019-01-18

1394 Crowdsourced MRI quality metrics and expert quality annotations for training of humans and machines

Esteban, O.; Blair, R. W.; Nielson, D. M.; Varada, J. C.; Marrett, S.; Thomas, A.; Poldrack, R.; Gorgolewski, K. J.

10.1101/420984 — bioengineering — Posted on 2019-01-18

1395 IMPROVING THE PERFORMANCE OF THE AMBER RNA FORCE FIELD BY TUNING THE HYDROGEN-BONDING INTERACTIONS

Kuhrova, P.; Mlynsky, V.; Zgarbova, M.; Krepl, M.; Bussi, G.; Best, R. B.; Otyepka, M.; Sponer, J.; Banas, P.

10.1101/410993 — biochemistry — Posted on 2019-01-18

1396 Viral Invasion Fitness Across a Continuum from Lysis to Latency

Weitz, J. S.; Li, G.; Gulbudak, H.; Cortez, M. H.; Whitaker, R. J.

10.1101/296897 — ecology — Posted on 2019-01-18

1397 Current Models of Speech Motor Control: A Control-Theoretic Overview of Architectures & Properties

Parrell, B.; Lammert, A. C.; Ciccarelli, G.; Quatieri, T. F.

10.1101/197285 — neuroscience — Posted on 2019-01-18

1398 Sound induces change in orientation preference of V1 neurons: Audio-visual cross-influence

Chanauria, N.; Bharmauria, V.; Bachatene, L.; Cattan, S.; Rouat, J.; Molotchnikoff, S.

10.1101/269589 — neuroscience — Posted on 2019-01-18

1399 Cerebellar grey matter volume is associated with cognitive function and psychopathology in adolescence

Moberget, T.; Alnaes, D.; Kaufmann, T.; Doan, N. T.; Cordova-Palomera, A.; Norbom, L. B.; Rokicki, J.; van der Meer, D.; Andreassen, O. A.; Westlye, L. T.

10.1101/288134 — neuroscience — Posted on 2019-01-18

1400 Hellbender Salamanders (Cryptobranchus alleganiensis) Exhibit An Ontogenetic Shift In Microhabitat Use In A Blue Ridge Physiographic Region Stream

Hecht, K. A.; Freake, M. J.; Nickerson, M. A.; Colclough, P.

10.1101/139766 — ecology — Posted on 2019-01-18

1401 Human extinction learning is accelerated by an angiotensin antagonist via ventromedial prefrontal cortex and its connections with basolateral amygdala

Zhou, F.; Geng, Y.; Li, J.; Feng, P.; Liu, C.; Zhao, W.; Feng, T.; Guastella, A.; Kendrick, K.; Becker, B.

10.1101/512657 — clinical trials — Posted on 2019-01-18

1402 Line drawings reveal the structure of internal visual models conveyed by cortical feedback.

Morgan, A. T.; Petro, L. S.; Muckli, L.

10.1101/041186 — neuroscience — Posted on 2019-01-18

1403 Acute Myeloid Leukemia Driven by the CALM-AF10 Fusion Gene is Dependent on BMI1

Barbosa, K.; Ghosh, A.; Deshpande, A.; Chen, B.-R.; Sun, Y.; Weetall, M.; Armstrong, S. A.; Bohlander, S. K.; Deshpande, A. J.

10.1101/524066 — cancer biology — Posted on 2019-01-18

1404 RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling

Garay, P. M.; Chen, A.; Tsukahara, T.; Kohen, R.; Althaus, J. C.; Wallner, M. A.; Giger, R. J.; Sutton, M. A.; Iwase, S.

10.1101/523456 — neuroscience — Posted on 2019-01-18

1405 Development of a Prediction Model for Incident Atrial Fibrillation using Machine Learning Applied to Harmonized Electronic Health Record Data

Tiwari, P.; Colborn, K. L.; Smith, D. E.; Xing, F.; Ghosh, D.; Rosenberg, M. A.

10.1101/520866 — epidemiology — Posted on 2019-01-18

1406 Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank

Howe, L. D.; Kanayalal, R.; Beaumont, R.; Davies, A. R.; Frayling, T. M.; Harrison, S.; Jones, S. E.; Sassi, F.; Wood, A. R.; Tyrrell, J.

10.1101/524488 — epidemiology — Posted on 2019-01-18

1407 Knowledge, attitude and practices on dengue fever among paediatric and adult in-patients in Metro Manila, Philippines

Herbuela, V. R. D. M.; de Guzman, F. S.; Sobrepena, G. D.; Claudio, A. B. F.; Tomas, A. C. V.; Arriola-delos Reyes, C. M.; Regalado, R. A.; Teodoro, M. M.; Watanabe, K.

10.1101/520981 — epidemiology — Posted on 2019-01-18

1408 Emergence of the Zika virus Asian lineage in Angola

Hill, S. C.; Vasconcelos, J.; Neto, Z.; Jandondo, D.; Ze-Ze, L.; Santana Aguiar, R.; Xavier, J.; Theze, J.; Mirandela, M.; Micolo Candido, A. L.; Vaz, F.; dos Santos Sebastiao, C.; Wu, C.-H.; Kraemer, M.; Melo, A.; Schamber-Reis, B. L.; de Azevedo, G. S.; Tanuri, A.; Higa, L. M.; Clemente, C.; Pereira da Silva, S.; da Silva Candido, D.; Claro, I. M.; Quibuco, D.; Domingos, C.; Pocongo, B.; Watts, A. G.; Khan, K.; Alcantara, L. C.; Sabino, E.; Lackritz, E.; Pybus, O. G.; Alves, M.-J.; Afonso, J.; Faria, N. R.

10.1101/520437 — epidemiology — Posted on 2019-01-18

1409 The effectiveness and cost effectiveness of a hospital avoidance program in a residential aged care facility

Carter, H.; Lee, X.; Dwyer, T.; Jeffrey, D.; O'Neill, B.; Doran, C.; Parkinson, L.; Osborne, S.; Reid-Searl, K.; Graves, N.

10.1101/523969 — epidemiology — Posted on 2019-01-18

1410 Benefits of improved air quality on aging lungs. Impacts of genetics and obesity

Huels, A.; Sugiri, D.; Abramson, M. J.; Hoffmann, B.; Schwender, H.; Ickstadt, K.; Kraemer, U.; Schikowski, T.

10.1101/521328 — epidemiology — Posted on 2019-01-18

1411 Enteropathogen seroepidemiology among children in low-resource settings

Arnold, B. F.; Martin, D. L.; Juma, J.; Mkocha, H.; Ochieng, J. B.; Cooley, G. M.; Omore, R.; Goodhew, E. B.; Morris, J. F.; Costantini, V.; Vinje, J.; Lammie, P. J.; Priest, J. W.

10.1101/522920 — epidemiology — Posted on 2019-01-18

1412 Capturing multiple-type interactions into practical predictors of type replacement following HPV vaccination

Man, I.; Auranen, K.; Wallinga, J. A.; Bogaards, J. A.

10.1101/523472 — epidemiology — Posted on 2019-01-18

1413 Use of a pandemic H1N1 strain with updated haemagglutinin and neuraminidase results in increased nasopharyngeal shedding and improved immunogenicity to Russian-backbone live attenuated influenza vaccine among children aged 2 - 4 years old: an open label, prospective, observational, phase 4 study in The Gambia.

Lindsey, B. B.; Jagne, Y. J.; Armitage, E. P.; Singanayagam, A.; Sallah, H. J.; Drammeh, S.; Senghore, E.; Mohammed, N. I.; Jeffries, D.; Hoschler, K.; Tregoning, J. S.; Meijer, A.; Clarke, E.; Dong, T.; Barclay, W.; Kampmann, B.; de Silva, T. I.

10.1101/519256 — clinical trials — Posted on 2019-01-18

1414 Healthcare related activity following kidney transplantation: an observational cohort study.

Murray, E. C.; Traynor, J.; Mark, P.; Geddes, C.; Kingsmore, D.; Stevenson, K.; Clancy, M.; Thomson, P.

10.1101/524421 — epidemiology — Posted on 2019-01-18

1415 A new image segmentation algorithm with applications in confocal microscopy analysis

Sanchez-Aragon, M.; Casares, F.

10.1101/524389 — systems biology — Posted on 2019-01-18

1416 The Prrx1 limb enhancer marks an adult population of injury-responsive, multipotent dermal fibroblasts

Currie, J. D.; Grosser, L.; Murawala, P.; Schuez, M.; Michel, M.; Tanaka, E. M.; Sandoval-Guzman, T.

10.1101/524124 — developmental biology — Posted on 2019-01-18

1417 Tau pathology in early Alzheimer’s disease disrupts selective neurophysiological networks dynamics

Kocagoncu, E.; Quinn, A.; Firouzian, A.; Cooper, E.; Greve, A.; Gunn, R.; Green, G.; Woolrich, M. W.; Henson, R. N.; Lovestone, S.; Deep and Frequent Phenotyping study team, ; Rowe, J. B.

10.1101/524355 — neuroscience — Posted on 2019-01-18

1418 Reproductive success in the barn owl is linked to partner compatibility in glucocorticoid levels

Beziers, P.; Jenni, L.; Roulin, A.; Almasi, B.

10.1101/517227 — evolutionary biology — Posted on 2019-01-18

1419 Portion size does not influence food consumption in rats

Naneix, F.; Pinder, S. C.; Summers, M. Y.; Rouleau, R. M.; Robinson, E.; Myers, K. P.; McCutcheon, J. E.

10.1101/524272 — animal behavior and cognition — Posted on 2019-01-18

1420 Distinct genetic signatures of cortical and subcortical regions associated with human memory

Tan, P. K.; Ananyev, E.; Hsieh, P.-J.

10.1101/524116 — neuroscience — Posted on 2019-01-18

1421 Thalamus drives two complementary input strata of the neocortex in parallel

Egger, R.; Narayanan, R. T.; Udvary, D.; Bast, A.; Guest, J. M.; Das, S.; de Kock, C. P. J.; Oberlaender, M.

10.1101/524298 — neuroscience — Posted on 2019-01-18

1422 Survival of adult barn owls is linked to corticosterone levels

Beziers, P.; Korner, F.; Jenni, L.; Roulin, A.; Almasi, B.

10.1101/517201 — evolutionary biology — Posted on 2019-01-18

1423 Metabolic rates of prokaryotic microbes may inevitably rise with global warming

Smith, T. P.; Thomas, T. J. H.; Garcia-Carreras, B.; Sal, S.; Yvon-Durocher, G.; Bell, T.; Pawar, S.

10.1101/524264 — ecology — Posted on 2019-01-18

1424 Measuring amber initiator tRNA orthogonality in a genomically recoded organism

Vincent, R. M.; Wright, B. W.; Jaschke, P. R.

10.1101/524249 — synthetic biology — Posted on 2019-01-18

1425 Microbial predictors of environmental perturbations in coral reef ecosystems

Glasl, B.; Bourne, D. G.; Frade, P.; Thomas, T.; Schaffelke, B.; Webster, N. S.

10.1101/524173 — microbiology — Posted on 2019-01-18

1426 Distributed representations of protein domains and genomes and their compositionality

Viehweger, A.; Krautwurst, S.; Koenig, B.; Marz, M.

10.1101/524280 — genomics — Posted on 2019-01-18

1427 S. cerevisiae Srs2 helicase ensures normal recombination intermediate metabolism during meiosis and prevents accumulation of Rad51 aggregates

Hunt, L. J.; Ahmed, E.; Kaur, H.; Ahuja, J.; Hulme, L.; Chou, T.-C.; Lichten, M.; Goldman, A. S. H.

10.1101/524413 — genetics — Posted on 2019-01-18

1428 LipoGlo: A sensitive and specific reporter of atherogenic lipoproteins

Thierer, J. H.; Farber, S.; Ekker, S.

10.1101/522615 — genetics — Posted on 2019-01-18

1429 Modelling the evolution of viral oncogenesis

Murall, C. L.; Alizon, S.

10.1101/523373 — evolutionary biology — Posted on 2019-01-18

1430 Changes in fungal communities across a forest disturbance gradient

Shi, L.; Gbadamassi, D. G. O.; Ekananda, P.; Zang, H.; Xu, J.; Harrison, R. D.

10.1101/524132 — ecology — Posted on 2019-01-18

1431 Ethanol-induced conditioned place preference and aversion differentially alter plasticity in the bed nucleus of stria terminalis

Pati, D.; Pina, M. M.; Kash, T. L.

10.1101/519371 — neuroscience — Posted on 2019-01-18

1432 SWI/SNF component BAF250a coordinates OCT4 and WNT signaling pathway to control cardiac lineage differentiation

Lei, I.; Tian, S.; Chen, V.; Zhao, Y.; Wang, Z.

10.1101/524454 — developmental biology — Posted on 2019-01-18

1433 Integrin cytoplasmic domain and pITAM compete for spleen tyrosine kinase binding

Antenucci, L.; Hellman, M.; Hytonen, V. P.; Permi, P.; Ylanne, J.

10.1101/524447 — biochemistry — Posted on 2019-01-18

1434 Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

Kumar, V.; Doharey, P. K.; Gulati, S.; Meehan, J.; Martinez, M. G.; Hughes, K.; Mooers, B. H. M.; Cruz-Reyes, J.

10.1101/524702 — molecular biology — Posted on 2019-01-18

1435 Ponds, puddles, floodplains and dams in the Upper Xingu Basin: could we be witnessing the ‘lentification’ of deforested Amazonia?

Schiesari, L. C.; Ilha, P. R.; Negri, D. D. B.; Prado, P. I.; Grillitsch, B.

10.1101/524652 — ecology — Posted on 2019-01-18

1436 Managing genomic variant calling workflows with Swift/T

Ahmed, A.; Heldenbrand, J.; Asmann, Y.; Fadlelmola, F.; Katz, D.; Kendig, K.; Kendzior, M.; Li, T.; Ren, Y.; Rodriguez, E.; Weber, M.; Zermeno, J.; Wozniak, J.; Mainzer, L. S.

10.1101/524645 — bioinformatics — Posted on 2019-01-18

1437 Conformational coupling by trans-phosphorylation in calcium calmodulin dependent kinase II

Pandini, A.; Schulman, H.; Khan, S.

10.1101/524660 — neuroscience — Posted on 2019-01-18

1438 Direct visualization of membrane-spanning pores formed by a Leishmania amazonensis pore-forming cytolysin, as probed by atomic force microscopy

Castro-Gomes, T.; Vilela, J. M.; Andrade, M. S.; Beirao, P. S.; Frezard, F.; Horta, M. F.

10.1101/524686 — microbiology — Posted on 2019-01-18

1439 MicroRNA-222 regulates fluid shear stress-induced human nucleus pulposus cells degeneration through affecting c-Fos expression

Miao, G.; Yao, Y.; Ye, B.; Dai, L.; Liang, G.; Haixiong Miao , Yicun Yao , Baoqing Ye,

10.1101/524595 — cell biology — Posted on 2019-01-18

1440 Postnatal development of skeletal muscle in IUGR pigs: morphofunctional phenotype and molecular mechanisms

Almeida, F.; Pereira, A.; Felicioni, F.; Caldeira-Brant, A.; Magnabosco, D.; Bortolozzo, F.; Tsoi, S.; Dyck, M.; Dixon, W.; Martinelli, P.; Jorge, E.; Chiarini-Garcia, H.

10.1101/524629 — cell biology — Posted on 2019-01-18

1441 LINE-1 retrotransposition impacts the genome of human pre implantation embryos and extraembryonic tissues

Munoz-Lopez, M.; Vilar, R.; Philippe, C.; Rahbari, R.; Richardson, S. R.; Andres-Anton, M.; Widmann, T.; Cano, D.; Cortes, J. L.; Rubio-Roldan, A.; Guichard, E.; R. Heras, S.; Sanchez-Luque, F. J.; Morell, M.; Aguilar, E.; Garcia-Canadas, M.; Sanchez, L.; Macia, A.; Vilches, P.; Nieto-Perez, M. C.; Gomez-Martin, A.; Gonzalez-Alzaga, B.; Aguilar- Garduno, C.; Ewing, A. D.; Lacasana, M.; Alvarez, I. S.; Badge, R.; Faulkner, G. J.; Cristofari, G.; Garcia-Perez, J. L.

10.1101/522623 — genomics — Posted on 2019-01-18

1442 Effect of ceftiofur cessation and substitution with lincomycin-spectinomycin on extended-spectrum-beta-lactamase/AmpC genes and multidrug resistance in E. coli from a Canadian broiler production pyramid

Verrette, L.; Fairbrother, J. M.; Boulianne, M.

10.1101/521120 — microbiology — Posted on 2019-01-18

1443 Raman Spectroscopic comparative study of Oxytocin and Freeze-dried Extract of Uvariodendron anisatum Verdeck (Annonaceae) and their influence on diet induced obesity in Sprague Dawley rats

Birech, Z.; Mwangi, P. W.; Sehmi, P. K.; Nyaga, N. M.

10.1101/523555 — physiology — Posted on 2019-01-18

1444 Health workers’ perspectives on the outcomes, enablers, and barriers to the implementation of HIV “Treat All” guidelines in Abuja Nigeria

Odafe, S.; Stafford, K. A.; Gambo, A.; Onotu, D.; Swaminathan, M.; Dalhatu, I.; Ene, U.; Oladipo, A.; Mukhtar, A.; Ibrahim, R.; Ehoche, A.; Debem, H.; Boyd, A. T.; Aboje, S.; Gobir, B.; Charurat, M.

10.1101/523548 — epidemiology — Posted on 2019-01-18

1445 HIV-1 subtype C with PYxE insertion has enhanced binding of Gag-p6 to host cell protein ALIX and increased replication fitness

van Domselaar, R.; Njenda, D. T.; Rao, R. K.; Sönnerborg, A.; Singh, K.; Neogi, U.

10.1101/459156 — microbiology — Posted on 2019-01-18

1446 Comparative analysis of ionic strength tolerance between freshwater and marine Caulobacterales adhesins

Chepkwony, N. K.; Berne, C.; Brun, Y. V.

10.1101/523142 — microbiology — Posted on 2019-01-18

1447 Affective reactivity during adolescence: Associations with age, puberty and testosterone

Vijayakumar, N.; Pfeifer, J. H.; Flournoy, J. C.; Hernandez, L. M.; Dapretto, M.

10.1101/524033 — neuroscience — Posted on 2019-01-18

1448 The role of Caulobacter cell surface structures in colonization of the air-liquid interface

Fiebig, A.

10.1101/524058 — microbiology — Posted on 2019-01-18

1449 Ethanol stimulates trehalose production through a SpoT-DksA-AlgU dependent pathway in Pseudomonas aeruginosa

Harty, C. E.; Martins, D.; Doing, G.; Mould, D. L.; Clay, M. E.; Nguyen, D.; Hogan, D. A.

10.1101/523126 — microbiology — Posted on 2019-01-18

1450 Replicating Arabidopsis Model Leaf Surfaces for Phyllosphere Microbiology

Soffe, R.; Bernach, M.; Remus-Emsermann, M.; Nock, V.

10.1101/523985 — microbiology — Posted on 2019-01-18

1451 ESUCA: a pipeline for genome-wide identification of upstream open reading frames with evolutionarily conserved sequences and determination of the taxonomic range of their conservation

Takahashi, H.; Hayashi, N.; Yamashita, Y.; Naito, S.; Takahashi, A.; Fuse, K.; Endo, T.; Kojima, S.; Onouchi, H.

10.1101/524090 — bioinformatics — Posted on 2019-01-18

1452 Systemic signalling through TCTP1 controls lateral root formation in Arabidopsis

Branco, R.; Masle, J.

10.1101/523092 — plant biology — Posted on 2019-01-18

1453 Heartbeat evokes a dynamically changing cortical theta-synchronized network in the resting state

Kim, J.; Jeong, B.

10.1101/524108 — neuroscience — Posted on 2019-01-18

1454 Seasonal microbial dynamics on grapevine leaves under biocontrol and copper fungicide treatments

Gobbi, A.; Kyrkou, I.; Filippi, E.; Ellegaard-Jensen, L.; Hansen, L. H.

10.1101/523977 — microbiology — Posted on 2019-01-18

1455 Identification of flavone and its derivatives as potential inhibitors of transcriptional regulator LasR of Pseudomonas aeruginosa using virtual screening

Abelyan, N. N.; Grabski, H.; Tiratsuyan, S.

10.1101/523381 — bioinformatics — Posted on 2019-01-18

1456 A Spiking Neuron and Population Model based on the Growth Transform Dynamical System

Gangopadhyay, A.; Mehta, D.; Chakrabartty, S.

10.1101/523944 — neuroscience — Posted on 2019-01-18

1457 VPAC: Variational projection for accurate clustering of single-cell transcriptomic data

Chen, S.; Hua, K.; Cui, H.; Jiang, R.

10.1101/523993 — bioinformatics — Posted on 2019-01-18

1458 PRISM: a comprehensive 3D structure database for post-translational modifications and mutations with functional impact

Li, F.; Fan, C.; Marquez-Lago, T. T.; Leier, A.; Revote, J.; Jia, C.; Zhu, Y.; Smith, A. I.; Chou, K.-C.; Webb, G. I.; Liu, Q.; Wei, L.; Li, J.; Song, J.

10.1101/523308 — bioinformatics — Posted on 2019-01-18

1459 Environmental and epigenetic regulation of Rider retrotransposons in tomato

Benoit, M.; Drost, H.-G.; Catoni, M.; Gouil, Q.; Lopez-Gomollon, S.; Baulcombe, D. C.; Paszkowski, J.

10.1101/517508 — plant biology — Posted on 2019-01-18

1460 Development of Human Neuroblastomas in Mouse-Human Neural Crest Chimeras

Cohen, M. A.; Zhang, S.; Sengupta, S.; Ma, H.; Horton, B.; Bell, G. W.; George, R. E.; Spranger, S.; Jaenisch, R.

10.1101/523795 — cancer biology — Posted on 2019-01-18

1461 Usiigaci: Instance-aware cell tracking in stain-free phase contrast microscopy enabled by machine learning

Tsai, H.-F.; Gajda, J.; Sloan, T. F. W.; Rares, A.; Shen, A. Q.

10.1101/524041 — bioinformatics — Posted on 2019-01-18

1462 Organization and Regulation of Chromatin by Liquid-Liquid Phase Separation

Gibson, B. A.; Doolittle, L. K.; Jensen, L. E.; Gamarra, N.; Redding, S.; Rosen, M. K.

10.1101/523662 — biophysics — Posted on 2019-01-18

1463 Compartmentalized Biosynthesis of Mycophenolic Acid

Zhang, W.; Du, L.; Qu, Z.; Zhang, X.; Li, F.; Li, Z.; Qi, F.; Wang, X.; Jiang, Y.; Men, P.; Sun, J.; Cao, S.; Geng, C.; Qi, F.; Wan, X.; Liu, C.; Li, S.

10.1101/524025 — biochemistry — Posted on 2019-01-18

1464 Synaptonemal complex proteins direct and constrain the localization of crossover-promoting proteins during Caenorhabditis elegans meiosis

Cahoon, C. K.; Helm, J. M.; Libuda, D. E.

10.1101/523605 — genetics — Posted on 2019-01-17

1465 The Evolution of Genetic Bandwagoning

Solon, I.

10.1101/064493 — evolutionary biology — Posted on 2019-01-17

1466 β-catenin has an ancestral role in cell fate specification but not cell adhesion

Salinas-Saavedra, M.; Wikramanayake, A.; martindale, m. Q.

10.1101/520957 — developmental biology — Posted on 2019-01-17

1467 Active and repressed chromatin domains exhibit distinct nucleosome segregation during DNA replication

Escobar, T.; Oksuz, O.; Descostes, N.; Bonasio, R.; Reinberg, D.

10.1101/418707 — biochemistry — Posted on 2019-01-17

1468 De novo assembly of the Mongolian gerbil genome and transcriptome

Cheng, S.; Fu, Y.; Zhang, Y.; Xian, W.; Wang, H.; Grothe, B.; Lu, X.; Xu, X.; Klug, A.; McCullagh, E. A.

10.1101/522516 — genomics — Posted on 2019-01-17

1469 Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns

Kwasnieski, J. C.; Orr-Weaver, T. L.; Bartel, D. P.

10.1101/375204 — developmental biology — Posted on 2019-01-17

1470 Neural correlates of the effects of tDCS stimulation over the LIFG for phonological processing in dyslexia

Rodrigues de Almeida, L.; Hansen, P. C.

10.1101/522847 — neuroscience — Posted on 2019-01-17

1471 Artificial Dendritic Neurons Enable Self-Supervised Temporal Feature Extraction

Asabuki, T.; Fukai, T.

10.1101/517888 — neuroscience — Posted on 2019-01-17

1472 A biologically-informed polygenic score identifiesendophenotypes and clinical conditions associated with the insulinreceptor function on specific brain regions

Hari Dass, S. A.; McCracken, K.; Pokhvisneva, I.; Chen, L. M.; Garg, E.; Nguyen, T. T.; Wang, Z.; Barth, B.; Yaqubi, M.; McEwen, L. M.; MacIsaac, J. L.; Diorio, J.; Kobor, M. S.; O'Donnell, K. J.; Meaney, M. J.; Silveira, P.

10.1101/289983 — neuroscience — Posted on 2019-01-17

1473 Velocity estimation in reinforcement learning

Velazquez, C.; Villarreal, M.; Bouzas, A.

10.1101/432492 — animal behavior and cognition — Posted on 2019-01-17

1474 Dominant coral bacterium Endozoicomonas acroporae metabolizes DMSP

Tandon, K.; Chiang, P.-W.; Lu, C.-Y.; Yang, S.-H.; Chen, Y.-F.; Wada, N.; Chen, P.-Y.; Chang, H.-Y.; Chou, M.-S.; Chen, W.-M.; Tang, S.-L.

10.1101/519546 — ecology — Posted on 2019-01-17

1475 An ESCRT-LEM domain inner nuclear membrane protein surveillance system is poised to directly monitor the integrity of the nuclear envelope barrier and nuclear transport system

Thaller, D.; Allegretti, M.; Borah, S.; Ronchi, P.; Beck, M.; Lusk, C. P.

10.1101/523670 — cell biology — Posted on 2019-01-17

1476 Stable biphasic interfaces for open microfluidic platforms

Lee, U. N.; Berthier, J.; Yu, J.; Berthier, E.; Theberge, A. B.

10.1101/392258 — bioengineering — Posted on 2019-01-17

1477 A Pipeline for Fecal Host DNA Analysis by Absolute Quantification of LINE-1 and Mitochondrial Genomic Elements Using ddPCR

He, K.; Fujiwara, H.; Zajac, C.; Sandford, E.; Reddy, P.; Choi, S. W.; Tewari, M.

10.1101/522862 — molecular biology — Posted on 2019-01-17

1478 The symmetrical pattern of base-pair substitutions rates across the chromosome in Escherichia coli has multiple causes

Niccum, B. A.; Lee, H.; MohammedIsmail, W.; Tang, H.; Foster, P. L.

10.1101/523696 — microbiology — Posted on 2019-01-17

1479 Targeted Long-Read RNA Sequencing Demonstrates Transcriptional Diversity Driven by Splice-Site Variation in MYBPC3

Dainis, A.; Tseng, E.; Clark, T. A.; Hon, T.; Wheeler, M.; Ashley, E.

10.1101/522698 — genetics — Posted on 2019-01-17

1480 On the Complexity of Sequence to Graph Alignment

Jain, C.; Zhang, H.; Gao, Y.; Aluru, S.

10.1101/522912 — bioinformatics — Posted on 2019-01-17

1481 Submicron Crystals of the Parkinson’s Disease Substantia nigra: Calcium Oxalate, Titanium Dioxide and Iron Oxide

Heller, A.; Coffman, S. S.

10.1101/523878 — neuroscience — Posted on 2019-01-17

1482 A next generation approach to species delimitation reveals the role of hybridization in a cryptic species complex of corals

Quattrini, A. M.; Wu, T.; Soong, K.; Jeng, M.-S.; Benayahu, Y.; McFadden, C. S.

10.1101/523936 — evolutionary biology — Posted on 2019-01-17

1483 Spatial control of oxygen delivery to 3D cultures alters cancer cell growth and gene expression

Wulftange, W. W.; Rose, M. A.; Garmendia-Cedillos, M.; da Silva, D.; Poprawski, J. E.; Srinivasachar, D.; Sullivan, T.; Lim, L.; Bliskovsky, V. V.; Hall, M. D.; Pohida, T. J.; Robey, R. W.; Morgan, N. Y.; Gottesman, M.

10.1101/522656 — bioengineering — Posted on 2019-01-17

1484 How macroecology affects macroevolution: the interplay between extinction intensity and trait-dependent extinction in brachiopods

Smits, P. D.

10.1101/523811 — paleontology — Posted on 2019-01-17

1485 A molecular phylogeny of Schizothoracinae (Teleostei: Cypriniformes: Cyprinidae) based on 12 protein-coding mitochondrial genes and RAG1 gene analysis

Du, Y.; Wang, T.; Qi, D.; Qi, D.; Li, W.; Zhong, J.; Chen, J.; Guo, S.; Ma, J.

10.1101/523639 — molecular biology — Posted on 2019-01-17

1486 Ecological and microbiological diversity of chigger mites, including vectors of scrub typhus, on small mammals across stratified habitats in Thailand

Chaisiri, K.; Gill, A. C.; Stekolnikov, A. A.; Hinjoy, S.; McGarry, J. W.; Darby, A. C.; Morand, S.; Makepeace, B.

10.1101/523845 — microbiology — Posted on 2019-01-17

1487 Understanding the variation in wood densities of trees and its implications for carbon assessments

Teegalapalli, K.; Pandey, C. K.; Osuri, A.; Ratnam, J.; Sankaran, M.

10.1101/523480 — ecology — Posted on 2019-01-17

1488 Reconstruction of Par polarity in apolar cells reveals a dynamic process of cortical polarization

Kono, K.; Yoshiura, S.; Fujita, I.; Okada, Y.; Shitamukai, A.; Shibata, T.; Matsuzaki, F.

10.1101/523589 — cell biology — Posted on 2019-01-17

1489 Dynamic pseudo-time warping of complex single-cell trajectories

Do, V. H.; Blazevic, M.; Monteagudo, P.; Borozan, L.; Elbassioni, K.; Laue, S.; Rojas Ringeling, F.; Matijevic, D.; Canzar, S.

10.1101/522672 — bioinformatics — Posted on 2019-01-17

1490 Plant seeds are primed by herbivore-induced plant volatiles

Maurya, A. K.; Pazouki, L.; Frost, C.

10.1101/522839 — plant biology — Posted on 2019-01-17

1491 A multimodal approach to identify clinically relevant parameters to monitor disease progression in a preclinical model of neuropediatric disease

Johnson, T. B.; Brudvig, J. J.; Lehtimäki, K. K.; Cain, J. T.; White, K. A.; Bragge, T.; Rytkönen, J.; Huhtala, T.; Timm, D.; Vihma, M.; Puoliväli, J. T.; Nurmi, A.; Weimer, J. M.

10.1101/522011 — pathology — Posted on 2019-01-17

1492 The differential contribution of pacemaker neurons to synaptic transmission in the pyloric network of the Jonah crab, Cancer borealis

Martinez, D.; Santin, J.; Schulz, D.; Nadim, F.

10.1101/523829 — neuroscience — Posted on 2019-01-17

1493 Select β-lactam combinations exhibit synergy against Mycobacterium abscessus in vitro

Story-Roller, E.; Maggioncalda, E.; Lamichhane, G.

10.1101/522649 — microbiology — Posted on 2019-01-17

1494 High genetic diversity of Plasmodium falciparum in the low transmission setting of the Kingdom of Eswatini

Roh, M. E.; Tessema, S. K.; Murphy, M.; Nhlabathi, N.; Mkhonta, N.; Vilakati, S.; Ntshalintshali, N.; Saini, M.; Maphalala, G.; Chen, A.; Wilheim, J.; Prach, L.; Gosling, R.; Kunene, S.; Hsiang, M.; Greenhouse, B.

10.1101/522896 — genetics — Posted on 2019-01-17

1495 Respiratory Muscle Training Improves Speech and Pulmonary Function in COPD Patients in a Home Health Setting - a Pilot Study

Bausek, N.; Havenga, L.; Aldarondo, S.

10.1101/523746 — physiology — Posted on 2019-01-17

1496 Induction of an alternative 5’ leader enhances translation of Inpp5e and resistance to oncolytic virus infection

Hoang, H.-D.; Graber, T.; Jia, J.-J.; Vaidya, N.; Gilchrist, V.; Li, W.; Gkogkas, C.; Jaramillo, M.; Jafarnejad, S. M.; Alain, T.

10.1101/522607 — molecular biology — Posted on 2019-01-17

1497 A Bimolecular Multicelular complementation system for the detection of syncytium formation: A new methodology for the identification of entry inhibitors

Garcia-Murria, M. J.; Exposito-Dominguez, N.; Mingarro, I.; Martinez-Gil, L.

10.1101/522540 — microbiology — Posted on 2019-01-17

1498 Unisexual reproduction promotes foraging for mating partners in the global human fungal pathogen Cryptococcus deneoformans

Fu, C.; Thielhelm, T. P.; Heitman, J.

10.1101/523894 — microbiology — Posted on 2019-01-17

1499 An Improved Human smORF Annnotation Workflow Combining De Novo Transcriptome Assembly and Ribo-Seq

Martinez, T. F.; Chu, Q.; Donaldson, C.; Tan, D.; Shokhirev, M. N.; Saghatelian, A.

10.1101/523860 — genomics — Posted on 2019-01-17

1500 Oceanic salt spray and herbivore pressure contribute to local adaptation of coastal perennial and inland annual ecotypes of the Seep Monkeyflower (Mimulus guttatus)

Popovic, D.; Lowry, D. B.

10.1101/523902 — evolutionary biology — Posted on 2019-01-17

1501 A model for the spatio-temporal design of gene regulatory circuits

Stoof, R.; Wood, A.; Goni-Moreno, A.

10.1101/522946 — synthetic biology — Posted on 2019-01-17

1502 Exercise-stimulated muscle ROS production and glucose uptake requires NADPH oxidase 2

Henriquez-Olguin, C.; Knudsen, J. R.; Raun, S. H.; Li, Z.; Dalbram, E.; Treebak, J. T.; Sylow, L.; Holmdahl, R.; Richter, E. A.; Jaimovich, E.; Jensen, T. E.

10.1101/522805 — physiology — Posted on 2019-01-17

1503 Neural correlates of the effects of tDCS stimulation over the LIFG for phonological processing in dyslexia

Rodrigues de Almeida, L.; Hansen, P. C.

10.1101/522847 — neuroscience — Posted on 2019-01-17

1504 Aβ-Positivity Predicts Cognitive Decline but Cognition Also Predicts Progression to Aβ-Positivity

Elman, J. A.; Panizzon, M. S.; Franz, C. E.; Gustavson, D. E.; Sanderson, M. E.; Lyons, M. J.; Kremen, W. S.

10.1101/523787 — neuroscience — Posted on 2019-01-17

1505 Synaptonemal complex proteins direct and constrain the localization of crossover-promoting proteins during Caenorhabditis elegans meiosis

Libuda, D. E.; Cahoon, C. K.; Helm, J. M.

10.1101/523605 — genetics — Posted on 2019-01-17

1506 Genetically distinct behavioral modules underlie natural variation in thermal performance curves

Stegeman, G. W.; Baird, S. E.; Ryu, W. S.; Cutter, A. D.

10.1101/523654 — evolutionary biology — Posted on 2019-01-17

1507 Ultra-fast fit-free analysis of complex fluorescence lifetime imaging via deep learning

Smith, J. T.; Yao, R.; Sinsuebphon, N.; Rudkouskaya, A.; Mazurkiewicz, J.; Barroso, M.; Yan, P.; Intes, X.

10.1101/523928 — bioengineering — Posted on 2019-01-17

1508 Comparative analysis of mitochondrial genome between UG93A and UG93B reveal common feature of 5’-end heterogeneity in mitochondrial genes of kenaf

Liao, X.; Zhao, Y.; Khan, A.; Kong, X.; Zhou, B.; Li, M.; Wei, M.; Peng, S.; Munsif, F.; Zhou, R.

10.1101/523647 — molecular biology — Posted on 2019-01-17

1509 Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods

Wright, C.; Rajpurohit, A.; Burke, E. E.; Williams, C.; Collado-Torres, L.; Kimos, M.; Brandon, N. J.; Cross, A. J.; Jaffe, A. E.; Weinberger, D. R.; Shin, J. H.

10.1101/445437 — genomics — Posted on 2019-01-17

1510 Eco-Evolutionary Feedbacks between Predator’s Linkage Disequilibrium and Prey Densities Maintain Diversity

Patel, S.; Buerger, R.

10.1101/523720 — evolutionary biology — Posted on 2019-01-17

1511 The Regime Shift Detector: a model to identify changes in dynamic rules governing populations

Bahlai, C. A.; Zipkin, E. F.

10.1101/522631 — ecology — Posted on 2019-01-17

1512 X-ray structures of two active secreted Bacteroides thetaiotaomicron C11 proteases in complex with peptide-based inhibitors

Roncase, E. J.; Gonzalez-Paez, G. E.; Wolan, D. W.

10.1101/522870 — biochemistry — Posted on 2019-01-17

1513 Hydraulic resistance of perivascular spaces in the brain

Tithof, J.; Kelley, D. H.; Mestre, H.; Nedergaard, M.; Thomas, J. H.

10.1101/522409 — neuroscience — Posted on 2019-01-17

1514 DNA Gap Repair-Mediated Site-Directed Mutagenesis is Different from Mandecki and Recombineering Approaches

Lyozin, G. T.; Brunelli, L.

10.1101/313155 — molecular biology — Posted on 2019-01-17

1515 PathMe: Merging and exploring mechanistic pathway knowledge

Domingo-Fernandez, D.; Mubeen, S.; Marin-Llao, J.; Hoyt, C.; Hofmann-Apitius, M.

10.1101/451625 — bioinformatics — Posted on 2019-01-17

1516 Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

Jones, E.; Matthews, Z.; Gul, L.; Sudhakar, P.; Treveil, A.; Divekar, D.; Buck, J.; Wrzesinski, T.; Jefferson, M.; Armstrong, S.; Hall, L.; Watson, A.; Carding, S.; Haerty, W.; Di Palma, F.; Mayer, U.; Powell, P.; Hautefort, I.; Wileman, T.; Korcsmaros, T.

10.1101/410027 — systems biology — Posted on 2019-01-17

1517 Genetic risk for coronary heart disease alters the influence of Alzheimer’s genetic risk on mild cognitive impairment

Elman, J. A.; Panizzon, M. S.; Logue, M. W.; Gillespie, N. A.; Neale, M. C.; Reynolds, C. A.; Gustavson, D. E.; Andreassen, O. A.; Dale, A. M.; Franz, C. E.; Lyons, M. J.; Kremen, W. S.

10.1101/432443 — genomics — Posted on 2019-01-17

1518 De novo assembly of the Mongolian gerbil genome and transcriptome

Cheng, S.; Fu, Y.; Zhang, Y.; Xian, W.; Wang, H.; Grothe, B.; Lu, X.; Xu, X.; Klug, A.; McCullagh, E. A.

10.1101/522516 — genomics — Posted on 2019-01-17

1519 SHARQnet - Sophisticated Harmonic Artifact Reduction in Quantitative Susceptibility Mapping using a Deep Convolutional Neural Network

Bollmann, S.; Kristensen, M. H.; Larsen, M. S.; Olsen, M.; Pedersen, M.; Ostergaard, L. R.; O'Brien, K.; Langkammer, C.; Fazlollahi, A.; Barth, M.

10.1101/522151 — neuroscience — Posted on 2019-01-17

1520 Rethinking pain threshold as a zone of uncertainty

Madden, V. J.; Kamerman, P. R.; Catley, M. J.; Bellan, V.; Russek, L. N.; Camfferman, D.; Moseley, L.

10.1101/521302 — neuroscience — Posted on 2019-01-17

1521 Physiological changes during cellular ageing in fission yeast drive non-random patterns of genome rearrangements

Ellis, D. A.; Reyes-Martin, F.; Rodriguez-Lopez, M.; Cotobal Martin, C.; Jeffares, D. C.; Tallada, V. A.; Bahler, J.

10.1101/522524 — genomics — Posted on 2019-01-17

1522 SpoIVA-SipL complex formation is essential for Clostridioides difficile spore assembly

Touchette, M. H.; Benito de la Puebla, H.; Ravinchandran, P.; Shen, A.

10.1101/522235 — microbiology — Posted on 2019-01-17

1523 The diversity of antibiotic resistance and virulence genes are correlated in human gut and environmental microbiomes

Escudeiro, P.; Pothier, J.; Dionisio, F.; Nogueira, T.

10.1101/298190 — genomics — Posted on 2019-01-17

1524 No evidence of functional co-adaptation between clustered microRNAs

Marco, A.

10.1101/274811 — evolutionary biology — Posted on 2019-01-17

1525 Hippocampal morphometry in sudden and unexpected death in epilepsy (SUDEP)

Somani, A.; Zborovschi, A.-B.; Liu, Y.; Patodia, S.; Michalak, Z.; Sisodiya, S.; Thom, M.

10.1101/522300 — pathology — Posted on 2019-01-17

1526 The time course of updating in running span

Kaur, S.; Norris, D.; Gathercole, S. E.

10.1101/522391 — neuroscience — Posted on 2019-01-17

1527 Smoking and the risk for bipolar disorder: causal evidence from a bidirectional Mendelian randomization study

Vermeulen, J.; Wootton, R.; Treur, J.; Sallis, H.; Jones, H.; Zammit, S.; van den Brink, W.; Goodwin, G.; de Haan, L.; Munafo, M.

10.1101/522268 — neuroscience — Posted on 2019-01-17

1528 Population persistence under high mutation rate: from evolutionary rescue to lethal mutagenesis

Anciaux, Y.; Lambert, A.; Ronce, O.; Roques, L.; Martin, G.

10.1101/521203 — evolutionary biology — Posted on 2019-01-17

1529 Effects of Parcellation and Threshold on Brain Connectivity Measures

Lacy, T. C.; Robinson, P. A.

10.1101/522060 — neuroscience — Posted on 2019-01-17

1530 Complete genome screening of clinical MRSA isolates identifies lineage diversity and provides full resolution of transmission and outbreak events

Sullivan, M. J.; Altman, D. R.; Chacko, K. I.; Ciferri, B.; Webster, E.; Pak, T. R.; Deikus, G.; Lewis-Sandari, M.; Khan, Z.; Beckford, C.; Rendo, A.; Samaroo, F.; Sebra, R.; Karam-Howlin, R.; Dingle, T.; Hamula, C.; Bashir, A.; Schadt, E.; Patel, G.; Wallach, F.; Kasarskis, A.; Gibbs, K.; van Bakel, H.

10.1101/522078 — microbiology — Posted on 2019-01-17

1531 Transposable elements drive reorganisation of 3D chromatin during early embryogenesis

Kruse, K.; Diaz, N.; Enriquez-Gasca, R.; Gaume, X.; Torres-Padilla, M.-E.; Vaquerizas, J. M.

10.1101/523712 — genomics — Posted on 2019-01-17

1532 Mosquito and primate ecology predict human risk of yellow fever virus spillover in Brazil

Childs, M. L.; Nova, N.; Colvin, J.; Mordecai, E. A.

10.1101/523704 — ecology — Posted on 2019-01-17

1533 Single-neuron representations of spatial memory targets in humans

Tsitsiklis, M.; Miller, J.; Qasim, S. E.; Inman, C. S.; Gross, R. E.; Willie, J. R.; Smith, E. H.; Sheth, S. A.; Schevon, C. A.; Sperling, M. R.; Sharan, A.; Stein, J. M.; Jacobs, J.

10.1101/523753 — neuroscience — Posted on 2019-01-17

1534 Non-apoptotic pioneer neutrophils initiate an endogenous swarming response in a zebrafish tissue injury model

Isles, H.; Muir, C. F.; Kadochnikova, A.; Loynes, C. A.; Kadirkamanathan, V.; Elks, P. M.; Renshaw, S. A.

10.1101/521450 — immunology — Posted on 2019-01-17

1535 Phase separation during mouse early embryonic development and underlying genetic and epigenetic correlations

Quan, H.; Liu, S.; Zhang, Y.; Xie, W.; Gao, Y. Q.

10.1101/521401 — developmental biology — Posted on 2019-01-17

1536 PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting

Erkes, A.; Mücke, S.; Reschke, M.; Boch, J.; Grau, J.

10.1101/522458 — bioinformatics — Posted on 2019-01-17

1537 The effects of aging on neural signatures of temporal regularity processing in sounds

Herrmann, B.; Buckland, C.; Johnsrude, I. S.

10.1101/522375 — neuroscience — Posted on 2019-01-17

1538 Attention Promotes the Neural Encoding of Prediction Errors

Smout, C. A.; Tang, M. F.; Garrido, M. I.; Mattingley, J. B.

10.1101/522185 — neuroscience — Posted on 2019-01-17

1539 Motion perception in the common marmoset

Cloherty, S. L.; Yates, J. L.; Graf, D.; DeAngelis, G. C.; Mitchell, J. F.

10.1101/522888 — neuroscience — Posted on 2019-01-17

1540 Divergence of piRNA pathway proteins affects piRNA biogenesis but not TE transcript level

Wang, L.; Barbash, D.; Kelleher, E.

10.1101/521773 — evolutionary biology — Posted on 2019-01-17

1541 Excessive deliberation in social anxiety

Hunter, L. E.; Meer, E. A.; Gillan, C. M.; Hsu, M.; Daw, N. D.

10.1101/522433 — animal behavior and cognition — Posted on 2019-01-17

1542 Evolutionary games with environmental feedbacks

Tilman, A. R.; Plotkin, J.; Akcay, E.

10.1101/493023 — evolutionary biology — Posted on 2019-01-17

1543 Dominant coral bacterium Endozoicomonas acroporae metabolizes DMSP

Tandon, K.; Chiang, P.-W.; Lu, C.-Y.; Yang, S.-H.; Chen, Y.-F.; Wada, N.; Chen, P.-Y.; Chang, H.-Y.; Chou, M.-S.; Chen, W.-M.; Tang, S.-L.

10.1101/519546 — ecology — Posted on 2019-01-17

1544 Conjunction or co-activation? A multi-level MVPA approach to task set representations

Deraeve, J.; Vassena, E.; Alexander, W.

10.1101/521385 — neuroscience — Posted on 2019-01-17

1545 Genome-wide epistasis and co-selection study using mutual information

Pensar, J.; Puranen, S.; MacAlasdair, N.; Kuronen, J.; Tonkin-Hill, G.; Pesonen, M.; Arnold, B.; Xu, Y.; Sipola, A.; Sanchez-Buso, L.; Lees, J. A.; Chewapreecha, C.; Bentley, S. D.; Harris, S. R.; Parkhill, J.; Croucher, N. J.; Corander, J.

10.1101/523407 — genomics — Posted on 2019-01-17

1546 Direct synthesis of EM-visible gold nanoparticles on genetically encoded tags for single-molecule visualization in cells

Jiang, Z.; Jin, X.; Li, Y.; Liu, S.; Liu, X.-M.; Wang, Y.-Y.; Zhao, P.; Cai, X.; Liu, Y.; Tang, Y.; Sun, X.; Liu, Y.; Hu, Y.; Li, M.; Cai, G.; Qi, X.; Chen, S.; Du, L.-L.; He, W.

10.1101/520999 — biophysics — Posted on 2019-01-17

1547 Design principles for open source bioinstrumentation: the poseidon syringe pump system as an example

Booeshaghi, A. S.; da Veiga Beltrame, E.; Bannon, D.; Gehring, J.; Pachter, L.

10.1101/521096 — bioengineering — Posted on 2019-01-17

1548 Fear contagion in zebrafish: a behaviour affected by familiarity

Fernandes da Silva, P.; Garcia de Leaniz, C.; Luchiari, A. C.

10.1101/521187 — animal behavior and cognition — Posted on 2019-01-17

1549 How sample heterogeneity can obscure the signal of microbial interactions

Armitage, D. W.; Jones, S. E.

10.1101/520668 — microbiology — Posted on 2019-01-17

1550 Instantaneous polarized light imaging reveals activity dependent structural changes of dendrites in mouse hippocampal slices

Koike-Tani, M.; Tominaga, T.; Oldenbourg, R.; Tani, T.

10.1101/523571 — biophysics — Posted on 2019-01-17

1551 PaKman: Scalable Assembly of Large Genomes on Distributed Memory Machines

Ghosh, P.; Krishnamoorthy, S.; Kalyanaraman, A.

10.1101/523068 — bioinformatics — Posted on 2019-01-17

1552 Causal evidence supporting the proposal that dopamine transients function as a temporal difference prediction error

Maes, E. J.; Sharpe, M. J.; Gardner, M. P.; Chang, C. Y.; Schoenbaum, G.; Iordanova, M. D.

10.1101/520965 — neuroscience — Posted on 2019-01-17

1553 Cerebellar disruption impairs working memory during evidence accumulation

Deverett, B.; Kislin, M.; Tank, D. W.; Wang, S. S.-.H.

10.1101/521849 — neuroscience — Posted on 2019-01-17

1554 Predictive markers for Parkinson’s disease using deep neural nets on neuromelanin sensitive MRI

Shinde, S.; Prasad, S.; Saboo, Y.; kaushick, R.; Saini, J.; Pal, P. K.; Ingalhalikar, M.

10.1101/523100 — neuroscience — Posted on 2019-01-17

1555 NWB:N 2.0: An Accessible Data Standard for Neurophysiology

Ruebel, O.; Tritt, A.; Dichter, B.; Braun, T.; Cain, N.; Clack, N.; Davidson, T. J.; Dougherty, M.; Fillion-Robin, J.-C.; Graddis, N.; Grauer, M.; Kiggins, J. T.; Niu, L.; Ozturk, D.; Schroeder, W.; Soltesz, I.; Sommer, F. T.; Svoboda, K.; Ng, L.; Frank, L. M.; Bouchard, K.

10.1101/523035 — neuroscience — Posted on 2019-01-17

1556 Complete genome sequence of Escherichia coli C - an old model organism with a new application in biofilm research

Krol, J. E.; Hall, D. C.; Balashov, S.; Pastor, S.; Siebert, J.; McCaffrey, J.; Lang, S.; Ehrlich, R.; Earl, J.; Mell, J. C.; Xiao, M.; Ehrlich, G. D.

10.1101/523134 — microbiology — Posted on 2019-01-17

1557 Genomic and epidemiological evidence of a dominant Panton-Valentine leucocidin-positive Methicillin Resistant Staphylococcus aureus lineage in Sri Lanka with spread to the United Kingdom and Australia

McTavish, S. M.; Snow, S. J.; Cook, E. C.; Pichon, B.; Coleman, S.; Coombs, G.; Pang, S.; Arias, C.; Diaz, L.; Boldock, E.; Davies, S.; Udukala, M.; Kearns, A.; Siribaddana, S.; de Silva, T.

10.1101/521260 — microbiology — Posted on 2019-01-17

1558 phyloFlash -- Rapid SSU rRNA profiling and targeted assembly from metagenomes

Gruber-Vodicka, H. R.; Seah, B. K.; Pruesse, E.

10.1101/521922 — bioinformatics — Posted on 2019-01-17

1559 Mechanistic Analyses of Supercoiling Behaviors of DNA in Nucleosomes and Chromatins

Zhang, H.; Li, T.

10.1101/523084 — biochemistry — Posted on 2019-01-17

1560 A multimodal approach to identify clinically relevant parameters to monitor disease progression in a preclinical model of neuropediatric disease

Johnson, T. B.; Brudvig, J. J.; Lehtimäki, K. K.; Cain, J. T.; White, K. A.; Bragge, T.; Rytkönen, J.; Huhtala, T.; Timm, D.; Vihma, M.; Puoliväli, J. T.; Nurmi, A.; Weimer, J. M.

10.1101/522011 — pathology — Posted on 2019-01-17

1561 Repetitive mild concussion in subjects with a vulnerable cholinergic system: lasting cholinergic-attentional impairments in CHT+/- mice.

Koshy Cherian, A.; Tronson, N.; Parikh, V.; Blakely, R.; Sarter, M.

10.1101/521484 — neuroscience — Posted on 2019-01-17

1562 The behavioral phenotype of early life adversity: a 3-level meta-analysis of rodent studies

Bonapersona, V.; Kentrop, J.; Van Lissa, C. J.; van der Veen, R.; Joels, M.; Sarabdjitsingh, R. A.

10.1101/521245 — neuroscience — Posted on 2019-01-17

1563 A language-familiarity effect on the recognition of computer-transformed vocal emotional cues

Nakai, T.; Rachman, L.; Arias, P.; Okanoya, K.; Aucouturier, J.-J.

10.1101/521641 — neuroscience — Posted on 2019-01-17

1564 Better ears with eyes open: effects of multisensory stimulation with nonconscious visual stimuli on auditory learning

Avila, M.; Ruggiero, R.; Pereira Leite, J.; Bueno-Junior, L.; Del-Ben, C. M.

10.1101/519900 — neuroscience — Posted on 2019-01-17

1565 The Efficacy of the Antimicrobial Peptide Melittin and the Enzyme DNase I Against E. coli Biofilms

Phillips, A.

10.1101/523159 — microbiology — Posted on 2019-01-17

1566 A natural, conditional gene drive in plants

Conner, A. J.; Jacobs, J.

10.1101/519884 — plant biology — Posted on 2019-01-17

1567 Reconfiguration of neuronal subpopulation associated with disease-associated microglia in human Alzheimer’s disease brain

Choi, H.; Choi, Y.; Hwang, D. W.; Lee, D. S.

10.1101/522987 — neuroscience — Posted on 2019-01-17

1568 Probing Neural Networks for Dynamic Switches of Communication Pathways

Finger, H.; Gast, R.; Gerloff, C.; Engel, A. K.; König, P.

10.1101/523522 — neuroscience — Posted on 2019-01-17

1569 Conflicting Bottom-up and Top-down Signals during Misrecognition of Visual Objects

Abdelhack, M.; Kamitani, Y.

10.1101/521252 — neuroscience — Posted on 2019-01-17

1570 Auditory-Visual Interactions in the Blind with Artificial Vision: Are Multisensory Perceptions Restored After Decades of Blindness?

Stiles, N. R. B.; Patel, V. R.; Weiland, J. D.

10.1101/519850 — neuroscience — Posted on 2019-01-17

1571 Evolving super stimuli for real neurons using deep generative networks

Ponce, C. R.; Xiao, W.; Schade, P.; Hartmann, T. S.; Kreiman, G.; Livingstone, M. S.

10.1101/516484 — neuroscience — Posted on 2019-01-17

1572 Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, L. R.; Zeng, J.; Sidorenko, J.; Yengo, L.; Moser, G.; Kemper, K. E.; Wang, H.; Zheng, Z.; Magi, R.; Esko, T.; Metspalu, A.; Wray, N. R.; Goddard, M. E.; Yang, J.; Visscher, P. M.

10.1101/522961 — genetics — Posted on 2019-01-17

1573 Consistency of SVDQuartets and Maximum Likelihood for Coalescent-based Species Tree Estimation

Wascher, M.; Kubatko, L.

10.1101/523050 — evolutionary biology — Posted on 2019-01-17

1574 Disharmony of the world’s island floras

Koenig, C.; Weigelt, P.; Taylor, A.; Stein, A.; Dawson, W.; Essl, F.; Pergl, J.; Pysek, P.; van Kleunen, M.; Winter, M.; Chatelain, C.; Wieringa, J. J.; Krestov, P.; Kreft, H.

10.1101/523464 — ecology — Posted on 2019-01-17

1575 BigMPI4py: Python module for parallelization of Big Data objects

Ascension, A. M.; Arauzo-Bravo, M. J.

10.1101/517441 — bioinformatics — Posted on 2019-01-17

1576 Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil

Mohammadkhani, A.; James, M.; Aston-Jones, G.

10.1101/521633 — animal behavior and cognition — Posted on 2019-01-17

1577 Black sea cucumber (Holothuria atra Jaeger, 1833) protects Caenorhabditis elegans against Pseudomonas aeruginosa infection

Lee, W.-T.; Tan, B.-K.; Eng, S.-A.; Yuen, G. C.; Chan, K. L.; Sim, Y. K.; Sulaiman, S. F.; Chong, A. S.-C.

10.1101/515783 — pharmacology and toxicology — Posted on 2019-01-17

1578 Sequence learning is driven by improvements in motor planning

Ariani, G.; Diedrichsen, J.

10.1101/523423 — neuroscience — Posted on 2019-01-17

1579 Molecular design, optimization and genomic integration of chimeric B cell receptors in murine B cells

Pesch, T.; Bonati, L.; Kelton, W.; Parola, C.; Ehling, R. A.; Csepregi, L.; Kitamura, D.; Reddy, S. T.

10.1101/516369 — immunology — Posted on 2019-01-17

1580 Understanding the variation in wood densities of trees and its implications for carbon assessments

Teegalapalli, K.; Pandey, C. K.; Osuri, A.; Ratnam, J.; Sankaran, M.

10.1101/523480 — ecology — Posted on 2019-01-17

1581 An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes

Schaich, M.; Cama, J.; Al Nahas, K.; Sobota, D.; Jahnke, K.; Deshpande, S.; Dekker, C.; Keyser, U. F.

10.1101/523431 — biophysics — Posted on 2019-01-17

1582 Differential Effector Response of Amnion- and Adipose-Derived Mesenchymal Stem Cells to Inflammation; Implications for Intradiscal Therapy

Borem, R.; Madeline, A.; Bowman, M.; Gill, S.; Tokish, J.; Mercuri, J.

10.1101/523001 — bioengineering — Posted on 2019-01-17

1583 Empowering conservation practice with efficient and economical genotyping from poor quality samples using mPCRseq

Natesh, M.; Taylor, R.; Truelove, N.; Hadly, E.; Palumbi, S.; Petrov, D.; Ramakrishnan, U.

10.1101/349472 — genomics — Posted on 2019-01-17

1584 Molecular and functional heterogeneity of cancer associated fibroblasts in high-grade serous ovarian cancer

Hussain, A.; Voisin, V.; Poon, S.; Dmytryshyn, J.; Meens, J.; Paterson, J.; Clarke, B.; Bernardini, M.; Bader, G.; Neel, B.; Ailles, L.

10.1101/519728 — cancer biology — Posted on 2019-01-17

1585 RPA phosphorylation regulates DNA resection

Soniat, M. M.; Myler, L. R.; Paull, T. T.; Finkelstein, I. J.

10.1101/517771 — biophysics — Posted on 2019-01-17

1586 Machine learning applied to predicting microorganism growth temperatures and enzyme catalytic optima

Li, G.; Rabe, K. S.; Nielsen, J.; Engqvist, M. K.

10.1101/522342 — bioinformatics — Posted on 2019-01-17

1587 Development of an ELISA-Based Method for Testing Aflatoxigenicity and Aflatoxigenic Variability among Aspergillus species in Culture

obonyo, m.; Toroitich, F.; Lagat, M. K.

10.1101/523506 — microbiology — Posted on 2019-01-17

1588 Adapting the ELEAT: Early Life Exposure Assessment Tool) to Portugal - a pilot study to tackle gene-environment interactions in Autism Spectrum Disorder

Rasga, C.; Santos, J. X.; Lopes, A. L.; Marques, A. R.; Vilela, J.; Asif, M.; Oliveira, G.; Bennett, D.; Walker, C.; Schmid, R.; Vicente, A. M.

10.1101/520593 — developmental biology — Posted on 2019-01-17

1589 Scalable multi-component linear mixed models with application to SNP heritability estimation

Pazokitoroudi, A.; Wu, Y.; S. Burch, K.; Hou, K.; Pasaniuc, B.; Sankararaman, S.

10.1101/522003 — bioinformatics — Posted on 2019-01-17

1590 3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients

Dincer, C.; Kaya, T.; Keskin, O.; Gursoy, A.; Tuncbag, N.

10.1101/523563 — systems biology — Posted on 2019-01-17

1591 Thiel Embalming Pre-Frozen Cadavers: A Mouse Model

Alshehry, M.; Kandil, M.; Alzahrani, R.; Soames, R.

10.1101/523514 — scientific communication and education — Posted on 2019-01-17

1592 Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Sundar, V. S.; Thompson, P.; Andreassen, O. A.; Dale, A. M.

10.1101/498550 — genetics — Posted on 2019-01-17

1593 Sparse Binary Relation Representations for Genome Graph Annotation

Karasikov, M.; Mustafa, H.; Joudaki, A.; Javadzadeh-No, S.; Rätsch, G.; Kahles, A.

10.1101/468512 — bioinformatics — Posted on 2019-01-17

1594 Human and mouse iPSC-derived astrocyte subtypes reveal vulnerability in Vanishing White Matter

Leferink, P.; Dooves, S.; Hillen, A.; Watanabe, K.; Jacobs, G.; Gasparotto, L.; Cornelissen-Steijger, P.; van der Knaap, M.; Heine, V.

10.1101/523233 — neuroscience — Posted on 2019-01-17

1595 Category knowledge biases sensory representations in human visual cortex.

Ester, E. F.; Sprague, T. C.; Serences, J. T.

10.1101/170845 — neuroscience — Posted on 2019-01-17

1596 Targeting of RBM10 to S1-1 Nuclear Bodies: Targeting Sequences and its Biological Significance

Wang, L.-Y.; Xiao, S.-J.; Kunimoto, H.; Tokunaga, K.; Kojima, H.; Kimura, M.; Yamamoto, T.; Yamamoto, N.; Hong, Z.; Nishio, K.; Yamane, H.; Tani, T.; Nakajima, K.; Iguchi, H.; Inoue, A.

10.1101/516831 — molecular biology — Posted on 2019-01-17

1597 GenomegaMap: within-species genome-wide dN/dS estimation from over 10,000 genomes

Wilson, D. J.; The CRyPTIC Consortium,

10.1101/523316 — genomics — Posted on 2019-01-17

1598 Termination of non-coding transcription in yeast relies on both a CTD-interaction domain and a CTD-mimic in Sen1

Han, Z.; Jasnovidova, O.; Tudek, A.; Kubicek, K.; Libri, D.; Stefl, R.; Porrua, O.

10.1101/433045 — genetics — Posted on 2019-01-17

1599 Culturing primary neurons from rat hippocampus and cortex

Sahu, M. P.; Nikkila, O.; Lagas, S.; Kolehmainen, S.; Castren, E.

10.1101/491118 — neuroscience — Posted on 2019-01-17

1600 Loss of YAP/TAZ impaired the proliferation and differentiation ability of neural progenitor cells

Kong, S.

10.1101/296053 — neuroscience — Posted on 2019-01-17

1601 Epigenetic suppression of interferon lambda receptor expression leads to an enhanced HuNoV replication in vitro

Arthur, S. E.; Sorgeloos, F.; Hosmillo, M.; Goodfellow, I.

10.1101/523282 — microbiology — Posted on 2019-01-17

1602 A gold standard method for human cell quantification after xenotransplantation

Bensalah, M.; Klein, P.; Riederer, I.; Chaouch, S.; Muraine, L.; Savino, W.; Butler-Bowne, G. S.; Trollet, C.; Mouly, V.; Bigot, A.; Negroni, E.

10.1101/523530 — cell biology — Posted on 2019-01-17

1603 Selective targeting of unipolar brush cell subtypes by cerebellar mossy fibers

Balmer, T. S.; Trussell, L.

10.1101/523266 — neuroscience — Posted on 2019-01-17

1604 Inhibition of MreB and ftsZ proteins to minimize E. coli biofilm formation

Charles, E.

10.1101/523167 — microbiology — Posted on 2019-01-17

1605 Parameter inference with analytical propagators for stochastic models of autoregulated gene expression

Veerman, F.; Popovic, N.; Marr, C.

10.1101/349431 — cell biology — Posted on 2019-01-17

1606 Tryptophan fluorescence quenching in β-lactam-interacting proteins is modulated by the structure of intermediates and final products of the acylation reaction

Triboulet, S.; Edoo, Z.; Compain, F.; Ourghanlian, C.; Dupuis, A.; Dubee, V.; Sutterlin, L.; Atze, H.; Etheve-Quelquejeu, M.; Hugonnet, J.-E.; Arthur, M.

10.1101/472381 — biochemistry — Posted on 2019-01-17

1607 Estimation the porosity of the valves of centric diatom Minidiscus vodyanitskiyi Lyakh & Bedoshvili using SEM images

Lyakh, A.; Bedoshvili, Y. D.; Shikhat, O. V.

10.1101/523258 — plant biology — Posted on 2019-01-17

1608 Relating growth potential and biofilm formation of Shigatoxigenic Escherichia coli to in planta colonisation and the metabolome of ready- to-eat crops

Merget, B.; Forbes, K. J.; Brennan, F.; McAteer, S. P.; Shepherd, T.; Strachan, N. J.; Holden, N.

10.1101/523175 — microbiology — Posted on 2019-01-17

1609 Gene Expression Predictions and Networks in Natural Populations Supports the Omnigenic Theory

Chateigner, A.; Lesage-Descauses, M.-C.; Rogier, O.; Jorge, V.; Leple, J.-C.; Brunaud, V.; Paysant-Le Roux, C.; Soubigou-Taconnat, L.; Martin-Magniette, M.-L.; Sanchez, L.; Segura, V.

10.1101/523365 — genomics — Posted on 2019-01-17

1610 Performance evaluation of inverse methods for identification and characterization of oscillatory brain sources: Ground truth validation & empirical evidences

Halder, T.; Talwar, S.; Jaiswal, A.; Banerjee, A.

10.1101/395780 — neuroscience — Posted on 2019-01-17

1611 Transcriptional analysis shows a robust host response to Toxoplasma gondii during early and late chronic infection in both male and female mice

Garfoot, A. L.; Cervantes, P. W.; Knoll, L. J.

10.1101/523183 — microbiology — Posted on 2019-01-17

1612 Identification of regulatory genes through global gene expression analysis of a Helicobacter pylori co-culture system

Hontecillas, R.; Tubau-Juni, N.; Bassaganya-Riera, J.; Leber, A.; Zoccoli-Rodriguez, V.; Kronsteiner, B.; Viladomiu, M.; Abedi, V.

10.1101/523274 — immunology — Posted on 2019-01-17

1613 Arbuscular Mycorrhizal Fungus (AMF) and reduction of arsenic uptake in lentil crops

Alam, M. Z.; Hoque, M. A.; McGee, R.; Boggs, L. C.

10.1101/522714 — microbiology — Posted on 2019-01-17

1614 Causal relationships between blood lipids and depression phenotypes: A Mendelian randomization analysis

So, H.-C.; Cheng, Y.-y.; Chau, C. K.-l.; Sham, P. C.

10.1101/363119 — genetics — Posted on 2019-01-17

1615 Bacterial community dynamics during embryonic and larval development of three confamilial echinoids

Carrier, T.; Reitzel, A.

10.1101/394478 — developmental biology — Posted on 2019-01-17

1616 Rcs phosphorelay activation in cardiolipin-deficient Escherichia coli reduces biofilm formation

Nepper, J. F.; Lin, Y. C.; Weibel, D. B.

10.1101/522219 — microbiology — Posted on 2019-01-17

1617 EphA7 functions as a receptor for cell-to-cell transmission of Kaposi’s sarcoma-associated herpesvirus into BJAB B cells and for cell-free virus infection by the related rhesus monkey rhadinovirus

Grosskopf, A. K.; Schlagowski, S.; Hörnich, B. F.; Fricke, T.; Desrosiers, R. C.; Hahn, A. S.

10.1101/522243 — microbiology — Posted on 2019-01-17

1618 Space-time clusters of dengue, chikungunya, and Zika cases in the city of Rio de Janeiro

Freitas, L. P.; Cruz, O. G.; Lowe, R.; Carvalho, M. S.

10.1101/521591 — epidemiology — Posted on 2019-01-17

1619 Carriage of a single strain of non-toxigenic Corynebacterium diphtheriae biovar Belfanti (Corynebacterium belfantii) in four patients with cystic fibrosis

Pivot, D.; Fanton, A.; Badell-Ocando, E.; Benouachkou, M.; Astruc, K.; Huet, F.; Amoureux, L.; Neuwirth, C.; Criscuolo, A.; Aho, S.; Toubiana, J.; Brisse, S.

10.1101/516880 — microbiology — Posted on 2019-01-17

1620 A novel technique for mapping viscosity in discrete subcellular locations with a BODIPY based fluorescent probe

Pytowski, L.; Foley, A. C.; Hernandez, Z.; Moon, N.; Donohoe, T.; Vaux, D. J.

10.1101/522532 — cell biology — Posted on 2019-01-16

1621 Cell Autonomous Neuroprotection by the Mitochondrial Uncoupling Protein 2 in a Mouse Model of Glaucoma

Hass, D. T.; Barnstable, C. J.

10.1101/522821 — neuroscience — Posted on 2019-01-16

1622 KLF4 protein stability regulated by interaction with pluripotency transcription factors overrides transcriptional control

Dhaliwal, N. K.; Abatti, L. E.; Mitchell, J. A.

10.1101/522680 — developmental biology — Posted on 2019-01-16

1623 The GRASP domain in Golgi Reassembly and Stacking Proteins: differences and similarities between lower and higher Eukaryotes

Mendes, L. F.; Fontana, N. A.; Oliveira, C. G.; Freire, M.; Lopes, J.; Melo, F.; Costa-Filho, A. J.

10.1101/522573 — biophysics — Posted on 2019-01-16

1624 HMGB1 orchestrates uterine macrophage trafficking to safeguard embryo implantation

Aikawa, S.; Deng, W.; Liang, X.; Yuan, J.; Bartos, A.; Sun, X.; Dey, S.

10.1101/522490 — developmental biology — Posted on 2019-01-16

1625 Computational modeling reveals frequency modulation of calcium-cAMP/PKA pathway in dendritic spines

Ohadi, D.; Schmitt, D. L.; Calabrese, B.; Halpain, S.; Zhang, J.; Rangamani, P.

10.1101/521740 — biophysics — Posted on 2019-01-16

1626 Scarless Enriched selection of Genome edited Human Pluripotent Stem Cells Using Induced Drug Resistance

Kim, K.-T.; Park, J.-C.; Lee, H.; Jang, H.-K.; Jin, Y.; Kim, W.; Lee, J.; Kim, H. H.; Bae, S.; Cha, H.-J.

10.1101/522383 — developmental biology — Posted on 2019-01-16

1627 Enhancing Cardiac Reprogramming by Suppressing Specific C-C Chemokine Signaling Pathways

Guo, Y.; Lei, I.; Tian, S.; Gao, W.; Hacer, K.; Li, Y.; Wang, S.; Liu, L.; Wang, Z.

10.1101/522995 — cell biology — Posted on 2019-01-16

1628 The HCN Channel Voltage Sensor Undergoes A Large Downward Motion During Hyperpolarization

Dai, G.; Aman, T. K.; DiMaio, F.; Zagotta, W. N.

10.1101/522581 — biophysics — Posted on 2019-01-16

1629 A DNA-based voltmeter for organelles

Saminathan, A.; Devany, J.; Pillai, K. S.; Veetil, A. T.; Schwake, M.; Krishnan, Y.

10.1101/523019 — biophysics — Posted on 2019-01-16

1630 Feature Design for Protein Interface hotspots using KFC2 and Rosetta

Seeger, F.; Little, A.; Chen, Y.; Woolf, T.; Cheng, H.; Mitchell, J. C.

10.1101/514372 — bioinformatics — Posted on 2019-01-16

1631 Fetus-derived IGF2 matches placental development to fetal demand

Sandovici, I.; Georgopoulou, A.; Hufnagel, A. S.; Schiefer, S. N.; Santos, F.; Hoelle, K.; Lam, B. Y. H.; Yeo, G. S. H.; Burling, K.; Lopez-Tello, J.; Reiterer, M.; Fowden, A. L.; Burton, G. J.; Sferruzzi-Perri, A. N.; Branco, C. M.; Constancia, M.

10.1101/520536 — developmental biology — Posted on 2019-01-16

1632 CryoAPEX - an electron tomography tool for subcellular localization of membrane proteins

Sengupta, R.; Poderycki, M. J.; Mattoo, S.

10.1101/522482 — cell biology — Posted on 2019-01-16

1633 Loss of a glutaredoxin gene underlies parallel evolution of trichome pattern in Antirrhinum

Tan, Y.; Barnbrook, M.; Wilson, Y.; Molnar, A.; Hudson, A.

10.1101/518183 — plant biology — Posted on 2019-01-16

1634 Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology

Sierksma, A.; Lu, A.; Salta, E.; Mancuso, R.; Zoco, J.; Blum, D.; Buee, L.; De Strooper, B.; Fiers, M.

10.1101/491902 — neuroscience — Posted on 2019-01-16

1635 The Caudate Nucleus Undergoes Dramatic and Unique Transcriptional Changes in Human Prodromal Huntington’s Disease Brain

Agus, F.; Crespo, D.; Myers, R. H.; Labadorf, A.

10.1101/520312 — genomics — Posted on 2019-01-16

1636 Direct Coupling Analysis of Epistasis in Allosteric Materials

Bravi, B.; Ravasio, R.; Brito, C.; Wyart, M.

10.1101/519116 — biophysics — Posted on 2019-01-16

1637 OSCA: a tool for omic-data-based complex trait analysis

Zhang, F.; Chen, W.; Zhu, Z.; Zhang, Q.; Deary, I. J.; Wray, N. R.; Visscher, P. M.; McRae, A. F.; Yang, J.

10.1101/445163 — bioinformatics — Posted on 2019-01-16

1638 Modeling Primary Fields of TMS Coils with the Fast Multipole Method

Makarov, S. N.; Navarro de Lara, L.; Noetscher, G. M.; Nummenmaa, A.

10.1101/514919 — neuroscience — Posted on 2019-01-16

1639 Serotonergic Psychedelics LSD & Psilocybin Increase theFractal Dimension of Cortical Brain Activity in Spatial and Temporal Domains

Varley, T.; Carhart-Harris, R.; Roseman, L.; Menon, D.; Stamatakis, E.

10.1101/517847 — neuroscience — Posted on 2019-01-16

1640 Visual delay affects force scaling and weight perception when lifting objects in virtual reality

van Polanen, V.; Tibold, R.; Nuruki, A.; Davare, M.

10.1101/504563 — neuroscience — Posted on 2019-01-16

1641 HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

Asquith, M.; Sternes, P. R.; Costello, M.-E.; Karstens, L.; Diamond, S.; Martin, T. M.; Spector, T. D.; le Cao, K.-A.; Rosenbaum, J. T.; Brown, M. A.

10.1101/517813 — microbiology — Posted on 2019-01-16

1642 Biobtree: A tool to search, map and visualize bioinformatics identifiers and special keywords

GUR, T.

10.1101/520841 — bioinformatics — Posted on 2019-01-16

1643 Quantitative modeling of STAT1 and STAT3 dynamics in IFNγ and IL-10 pathways uncovered robustness of anti-inflammatory STAT3 signaling.

Sarma, U.; Maiti, M.; BHADANGE, S.; NAIR, A.; Srivastava, A.; Saha, B.; Mukherjee, D.

10.1101/425868 — systems biology — Posted on 2019-01-16

1644 Mitochondrial Uncoupling Protein 2 Knockout Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in Glaucoma

Hass, D. T.; Barnstable, C. J.

10.1101/465153 — neuroscience — Posted on 2019-01-16

1645 Development and maintenance of synaptic structure is mediated by the alpha-tubulin acetyltransferase MEC-17/αTAT1

Teoh, J.-S.; Wang, W.; Chandhok, G.; Pocock, R.; Neumann, B.

10.1101/522904 — cell biology — Posted on 2019-01-16

1646 From spatio-temporal morphogenetic gradients to rhythmic patterning at the shoot apex

Galvan-Ampudia, C. S.; Cerutti, G.; Legrand, J.; Azais, R.; Brunoud, G.; Moussu, S.; Wenzl, C.; Lohmann, J.; Godin, C.; Vernoux, T.

10.1101/469718 — plant biology — Posted on 2019-01-16

1647 Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling

Garcia-Diaz, B.; Bachelin, C.; Coulpier, F.; Gerschenfeld, G.; Deboux, C.; Zujovic, V.; Charnay, P.; Topilko, P.; Baron-Van Evercooren, A.

10.1101/498261 — neuroscience — Posted on 2019-01-16

1648 Parkinson’s disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input

Baaske, M. K.; Kormann, E.; Holt, A. B.; Gulberti, A.; McNamara, C. G.; Poetter-Nerger, M.; Westphal, M.; Engel, A. K.; Hamel, W.; Brown, P.; Moll, C. K. E.; Sharott, A.

10.1101/513234 — neuroscience — Posted on 2019-01-16

1649 Temporal pattern separation in hippocampal neurons through multiplexed neural codes

Madar, A. D.; Ewell, L. A.; Jones, M. V.

10.1101/421479 — neuroscience — Posted on 2019-01-16

1650 Corazonin neuroendocrine pathway orchestrates stress-associated physiology in Drosophila

Zandawala, M.; Nguyen, T.; Johard, H.; Amcoff, M.; Paluzzi, J.-P.; Nassel, D. R.

10.1101/522441 — neuroscience — Posted on 2019-01-16

1651 The genetics of morphological and behavioral island traits in deer mice

Baier, F.; Hoekstra, H. E.

10.1101/443432 — evolutionary biology — Posted on 2019-01-16

1652 Effect of fire and thinning on fine-scale genetic structure and gene flow in fire-suppressed populations of sugar pine (Pinus lambertiana Douglas)

Lind, B. M.; North, M. P.; Maloney, P. E.; Eckert, A. J.

10.1101/448522 — ecology — Posted on 2019-01-16

1653 Pattern separation of spiketrains in hippocampal neurons

Madar, A. D.; Ewell, L. A.; Jones, M. V.

10.1101/107706 — neuroscience — Posted on 2019-01-16

1654 Dissociating Language and Thought in Human Reasoning

Coetzee, J. P.; Johnson, M. A.; Wu, A. D.; Iacoboni, M.; Monti, M.

10.1101/336123 — neuroscience — Posted on 2019-01-16

1655 Cyto-architecture constrains a photoactivation induced tubulin gradient in the syncytial Drosophila embryo

Thukral, S.; Kaity, B.; Dey, B.; Sharma, S.; Nandi, A.; Mitra, M.; Rikhy, R.

10.1101/520031 — developmental biology — Posted on 2019-01-16

1656 Pan-cancer whole genome analyses of metastatic solid tumors

Priestley, P.; Baber, J.; Lolkema, M.; Steeghs, N.; de Bruijn, E.; Duyvesteyn, K.; Haidari, S.; van Hoeck, A.; Onstenk, W.; Roepman, P.; Shale, C.; Voda, M.; Bloemendal, H.; Tjan-Heijnen, V.; van Herpen, C.; Labots, M.; Witteveen, P.; Smit, E.; Sleijfer, S.; Voest, E.; Cuppen, E.

10.1101/415133 — cancer biology — Posted on 2019-01-16

1657 Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes

Johnson, E. O.; LaVerriere, E.; Stanley, M.; Office, E.; Meyer, E.; Kawate, T.; Gomez, J.; Audette, R. E.; Bandyopadhyay, N.; Betancourt, N.; Delano, K.; Da Silva, I.; Davis, J.; Gallo, C.; Gardner, M.; Golas, A.; Guinn, K. M.; Korn, R.; McConnell, J. A.; Moss, C. E.; Murphy, K. C.; Nietupski, R.; Papavinasasundaram, K. G.; Pinkham, J. T.; Pino, P. A.; Proulx, M. K.; Ruecker, N.; Song, N.; Thompson, M.; Trujillo, C.; Wakabayashi, S.; Wallach, J. B.; Watson, C.; Ioerger, T. R.; Lander, E. S.; Hubbard, B. K.; Serrano-Wu, M. H.; Ehrt, S.; Fitzgerald, M.; Rubin, E. J.; Sassetti, C. M.; Schnappinge

10.1101/396440 — microbiology — Posted on 2019-01-16

1658 Reaction times and other skewed distributions: problems with the mean and the median

Rousselet, G. A.; Wilcox, R. R.

10.1101/383935 — neuroscience — Posted on 2019-01-16

1659 Enhanced bottom-up and reduced top-down fMRI activity is related to long-lasting non-reinforced behavioral change

Botvinik-Nezer, R.; Salomon, T.; Schonberg, T.

10.1101/363044 — neuroscience — Posted on 2019-01-16

1660 Modelling genotypes in their physical microenvironment to predict single- and multi-cellular behaviour

Voukantsis, D.; Kahn, K.; Hadley, M.; Wilson, R.; Buffa, F. M.

10.1101/360446 — bioinformatics — Posted on 2019-01-16

1661 Healthy ageing delays the neural processing of face features relevant for behaviour by 40 ms

Jaworska, K.; Yi, F.; Ince, R. A. A.; van Rijsbergen, N. J.; Schyns, P. G.; Rousselet, G. A.

10.1101/326009 — neuroscience — Posted on 2019-01-16

1662 A normalized drug response metric improves accuracy and consistency of drug sensitivity quantification in cell-based screening

Gupta, A.; Gautam, P.; Wennerberg, K.; Aittokallio, T.

10.1101/262568 — bioinformatics — Posted on 2019-01-16

1663 Multi-omic profiling of tyrosine kinase inhibitor-resistant K562 cells suggests metabolic reprogramming to promote cell survival

Noel, B. M.; Ouellette, S. B.; Marholz, L.; Dickey, D. M.; Navis, C.; Yang, T.-Y.; Nguyen, V.; Parker, S. J.; Bernlohr, D. A.; Sachs, Z.; Parker, L. L.

10.1101/308528 — cancer biology — Posted on 2019-01-16

1664 RNA Polymerase II is involved in 18S and 25S ribosomal RNA transcription, in Candida albicans

Fleischmann, J.; Rocha, M. A.; Hauser, P. V.

10.1101/510156 — molecular biology — Posted on 2019-01-16

1665 Calcium-driven regulation of voltage-sensing domains in BK channels

Latorre, R.; Lorenzo-Ceballos, Y.; Carrasquel-Ursulaez, W.; Castillo, K.; Alvarez, O.

10.1101/520429 — biophysics — Posted on 2019-01-16

1666 Bioproduction of single-stranded DNA from isogenic miniphage

Shepherd, T. R.; Du, R. R.; Huang, H.; Wamhoff, E.-C.; Bathe, M.

10.1101/521443 — bioengineering — Posted on 2019-01-16

1667 A mechanism for ligand gated strand displacement in ZTP riboswitch transcription regulation

Strobel, E. J.; Cheng, L.; Berman, K. E.; Carlson, P. D.; Lucks, J. B.

10.1101/521930 — biochemistry — Posted on 2019-01-16

1668 Measuring vision using innate behaviours in mice with intact and impairedretina function

Storchi, R.; Rodgers, J.; Gracey, M.; Martial, F. P.; Wynne, J.; Ryan, S.; Twining, C. J.; Cootes, T. F.; Killick, R.; Lucas, R. J.

10.1101/520247 — neuroscience — Posted on 2019-01-16

1669 Quality of life and satisfaction of users of total tissue-supported and implant-supported prostheses in the municipality of Macapa, Brazil

PARAGUASSU, E. C.; Cardenas, A. C. M.

10.1101/520197 — epidemiology — Posted on 2019-01-16

1670 Superadditive and subadditive dynamics are not inherent to the types of interacting threat

Haller-Bull, V.; Bode, M.

10.1101/522755 — ecology — Posted on 2019-01-16

1671 Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant

Diamantopolou, E.; Baxendale, S.; de la Vega de Leon, A.; Asad, A.; Holdsworth, C. J.; Abbas, L.; Gillet, V. J.; Wiggin, G. R.; Whitfield, T. T.

10.1101/520056 — developmental biology — Posted on 2019-01-16

1672 Age-dependent characterization of the carotid and cerebral artery morphologies in a transgenic mouse model of sickle cell anemia using ultrasound and microcomputed tomography

Rivera, C. P.; Li, L.; Cai, S.; Pei, N.; McAlear, G.; Bollavaram, K.; Ariyo, O. V.; Omojola, V. O.; Song, H.; Tan, W.; Huo, Y.; Platt, M. O.

10.1101/522748 — pathology — Posted on 2019-01-16

1673 Maternal antibodies provide strain-specific protection against infection with the Lyme disease pathogen in a wild rodent

Gomez-Chamorro, A.; Heinrich, V.; Sarr, A.; Roethlisberger, O.; Genne, D.; Jacquet, M.; Voordouw, M. J.

10.1101/522789 — immunology — Posted on 2019-01-16

1674 Organization in complex brain networks: energy distributions and phase shift

Sharma, S. K.; Singh, S. S.; Haobijam, D.; Malik, M. Z.; Singh, R. K. B.

10.1101/522797 — neuroscience — Posted on 2019-01-16

1675 Vibrotactile perception in the sole of the foot in people with normal glucose tolerance and type 2 diabetes

Peterson, M.; Pingel, R.; Rolandsson, O.; Dahlin, L. B.

10.1101/522706 — neuroscience — Posted on 2019-01-16

1676 How many days are needed to estimate accelerometry-assessed physical activity during pregnancy? Methodological analyses based on a cohort study using wrist-worn accelerometer

da Silva, S. G.; Evenson, K. R.; Ekelund, U.; da Silva, I. C. M.; Domingues, M. R.; da Silva, B. G. C.; Mendes, M. d. A.; Cruz, G. I. N.; Hallal, P. C.

10.1101/522722 — epidemiology — Posted on 2019-01-16

1677 Inquiry in Ridding the Democratic Republic of the Congo of sleeping sickness, a dream at our fingertips: comparing to the Epidemiology of human African trypanosomiasis in the Democratic Republic of the Congo 2002-2003

Tshima, G. K.

10.1101/522771 — epidemiology — Posted on 2019-01-16

1678 Image-derived Models of Cell Organization Changes During Differentiation of PC12 Cells

Ruan, X.; Johnson, G. R.; Bierschenk, I.; Nitschke, R.; Boerries, M.; Busch, H.; Murphy, R. F.

10.1101/522763 — cell biology — Posted on 2019-01-16

1679 Identification of the Calmodulin-dependent NAD+ kinase sustaining the elicitor-induced oxidative burst in plants

Dell'Aglio, E.; Giustini, C.; Kraut, A.; Coute, Y.; Mazars, C.; Matringe, M.; Finazzi, G.; Curien, G.

10.1101/521658 — plant biology — Posted on 2019-01-16

1680 Investigation of the transcriptional profile of human kidneys during machine perfusion reveals potential benefits of haemoadsorption

Ferdinand, J. R.; Hosgood, S. A.; Moore, T.; Ward, C. J.; Castro Dopico, T.; Nicholson, M. L.; Clatworthy, M. R.

10.1101/521294 — physiology — Posted on 2019-01-16

1681 Bacteriophage to Combat Biofilms in Hospital Drains

Huang, J. Y.

10.1101/522227 — microbiology — Posted on 2019-01-16

1682 Genes lost during the transition from land to water in cetaceans highlight genomic changes involved in aquatic adaptations

Huelsmann, M.; Hecker, N.; Springer, M. S.; Gatesy, J.; Sharma, V.; Hiller, M.

10.1101/521617 — evolutionary biology — Posted on 2019-01-16

1683 Using digital organisms to investigate the effect of whole genome duplication in (artificial) evolution

Yao, Y.; Carretero-Paulet, L.; Van de Peer, Y.

10.1101/521112 — evolutionary biology — Posted on 2019-01-16

1684 Phosgene Inhalation Causes Hemolysis and Acute Lung Injury

Aggarwal, S.; Jilling, T.; Doran, S.; Ahmad, I.; Eagen, J. E.; Gu, S.; Gillespie, M.; Albert, C. J.; Ford, D.; Oh, J.-Y.; Patel, R. P.; Matalon, S.

10.1101/521724 — physiology — Posted on 2019-01-16

1685 Regulation of modulatory cell activity across olfactory structures in Drosophila melanogaster

Zhang, X.; Coates, K.; Dacks, A.; Gunay, C.; Lauritzen, J. S.; Li, F.; Calle-Schuller, S. A.; Bock, D.; Gaudry, Q.

10.1101/522177 — neuroscience — Posted on 2019-01-16

1686 10Kin1day: A bottom-up neuroimaging initiative

van den Heuvel, M.; Scholtens, L.; van der Burgh, H.; Agosta, F.; Alloza, C.; Avancini, T.; Baron-Cohen, S.; Basaia, S.; Beyer, F.; Booij, L.; Cannon, D.; Chan, S.; Chen, E.; Cambridge Child Development Project, ; Crespo-Facorro, B.; Crone, E.; Dannlowski, U.; de Zwarte, S.; Diaz-Zuluaga, A.; Dietsche, B.; Donohoe, G.; Du Plessis, S.; Durston, S.; Emsley, R.; Filho, G.; Filippi, M.; Frodl, T.; Gasecki, D.; Goc, J.; Gorges, M.; Graff, B.; Grotegerd, D.; Hall, J.; Holleran, L.; Hopman, H.; Jäncke, L.; Jansen, A.; Jodzio, K.; Kaleda, V.; Kassubek, J.; Kharabian Masouleh, S.; Kircher, T.; Koevoe

10.1101/509554 — neuroscience — Posted on 2019-01-16

1687 Chromosome dynamics in bacteria: triggering replication at opposite location and segregation in opposite direction

Melendez, A. B.; Menikpurage, I. P.; Mera, P. E.

10.1101/521781 — microbiology — Posted on 2019-01-16

1688 Early steps in the evolution of vertical transmission revealed by a plant-bacterium symbiosis

De Meyer, F.; Danneels, B.; Acar, T.; Rasolomampianina, R.; Rajaonah, M. T.; Jeannoda, V.; Carlier, A.

10.1101/522367 — microbiology — Posted on 2019-01-16

1689 Conserved transcriptomic profile between mouse and human colitis allows temporal dynamic visualization of IBD-risk genes and unsupervised patient stratification

Czarnewski, P.; Parigi, S. M.; Sorini, C.; Diaz, O. E.; Das, S.; Gagliani, N.; Villablanca, E. J.

10.1101/520379 — immunology — Posted on 2019-01-16

1690 The genomic sequence and comparative genomic analysis of cultivated passion fruit(Passiflora edulis L.)

Wu, Y.; Tian, Q.; Liu, J.; Huang, Y.; Huang, W.; Xia, X.; Mou, H.; Yang, X.

10.1101/522128 — genomics — Posted on 2019-01-16

1691 First complete genome sequences of Zika virus from Midwest Brazil, 2015.

Vieira, C. J. d. S. P.; Machado, L. C.; Pena, L. J.; Bronzoni, R. V. d. M.; Wallau, G. d. L.

10.1101/521666 — genomics — Posted on 2019-01-16

1692 A 3D-printed hand-powered centrifuge for molecular biology

Byagathvalli, G.; Pomerantz, A.; Sinha, S.; Standeven, J.; Bhamla, M. S.

10.1101/519835 — bioengineering — Posted on 2019-01-16

1693 LRRK2 modifies α-syn pathology and spread in mouse models and human neurons

Bieri, G.; Brahic, M.; Bousset, L.; Couthouis, J.; Kramer, N.; Ma, R.; Nakayama, L.; Monbureau, M.; Defensor, E.; Schuele, B.; Shamloo, M.; Melki, R.; Gitler, A. D.

10.1101/522086 — neuroscience — Posted on 2019-01-16

1694 Molecular recognition of M1-linked ubiquitin chains by native and phosphorylated UBAN domains

Herhaus, L.; van den Bedem, H.; Tang, S.; Wakatsuki, S.; Dikic, I.; Rahighi, S.

10.1101/521815 — biophysics — Posted on 2019-01-16

1695 Dynamic Change of Electrostatic Field in TMEM16F Permeation Pathway Shifts Its Ion Selectivity

Ye, W.; Han, T. W.; He, M.; Jan, Y. N.; Jan, L. Y.

10.1101/515569 — biophysics — Posted on 2019-01-16

1696 Parallel signaling through IRE1α and PERK regulates pancreatic neuroendocrine tumor growth and survival

Moore, P. C.; Qi, J. Y.; Thamsen, M.; Ghosh, R.; Gliedt, M. J.; Meza-Acevedo, R.; Warren, R. E.; Hiniker, A.; Kim, G. E.; Maly, D. J.; Backes, B. J.; Papa, F. R.; Oakes, S. A.

10.1101/522102 — cancer biology — Posted on 2019-01-16

1697 Crystal Structure of the putative tail fiber protein gp53 from the Acinetobacter baumannii bacteriophage AP22

Sycheva, L.; Shneider, M.; Popova, A.; Ziganshin, R.; Volozhantsev, N.; Miroshnikov, K.; Leiman, P.

10.1101/518761 — biophysics — Posted on 2019-01-16

1698 Scalable multi-component linear mixed models with application to SNP heritability estimation

Pazokitoroudi, A.; Wu, Y.; S. Burch, K.; Hou, K.; Pasaniuc, B.; Sankararaman, S.

10.1101/522003 — bioinformatics — Posted on 2019-01-16

1699 Machine learning applied to predicting microorganism growth temperatures and enzyme catalytic optima

Li, G.; Rabe, K. S.; Nielsen, J.; Engqvist, M. K.

10.1101/522342 — bioinformatics — Posted on 2019-01-16

1700 Emergence of non-genetic heterogeneity in metabolic reactions

Tonn, M. K.; Thomas, P.; Barahona, M.; Oyarzun, D. A.

10.1101/522425 — systems biology — Posted on 2019-01-16

1701 Calcium/calmodulin-dependent protein kinase II regulates mammalian axon growth by affecting F-actin length in growth cone

Xi, F.; Xu, R.-j.; Xu, J.-h.; Wang, W.-h.; Ma, J.-j.; Wang, F.; Ma, Y.-x.; Qi, S.-b.; Zhang, J.-c.; Zhang, H.-n.; Qin, X.-z.; Chen, J.-q.; Li, B.; Liu, C.-m.; Yang, H.-l.; Meng, B.; Saijilafu,

10.1101/518076 — neuroscience — Posted on 2019-01-16

1702 Identification of potential new vaccine candidates in Salmonella typhi using reverse vaccinology and subtractive genomics-based approach

Mukherjee, S.; Gangopadhay, K.; Mukherjee, S. B.

10.1101/521518 — bioinformatics — Posted on 2019-01-16

1703 scruff: An R/Bioconductor package for preprocessing single-cell RNA-sequencing data

Wang, Z.; Hu, J.; Johnson, W. E.; Campbell, J. D.

10.1101/522037 — bioinformatics — Posted on 2019-01-16

1704 JuLI: accurate detection of DNA fusions in clinical sequencing for precision oncology

Shin, H.-T.; Kim, N. K. D.; Yun, J. W.; Lee, B.; Kyung, S.; Lee, K.-W.; Ryu, D.; Kim, J.; Bae, J. S.; Park, D.; Choi, Y.-L.; Lee, S.-H.; Ahn, M.-J.; Park, K.; Park, W.-Y.

10.1101/521039 — bioinformatics — Posted on 2019-01-16

1705 Intra-bin structural variant detection for whole genome sequencing data using U-net

Zhang, Y.-z.; Imoto, S.; Miyano, S.; Yamaguchi, R.

10.1101/503649 — bioinformatics — Posted on 2019-01-16

1706 YAMB: metagenome binning using nonlinear dimensionality reduction and density-based clustering

Korzhenkov, A.

10.1101/521286 — bioinformatics — Posted on 2019-01-16

1707 Stimulus-driven brain rhythms within the alpha band: The attentional-modulation conundrum

Keitel, C.; Keitel, A.; Benwell, C. S.; Daube, C.; Thut, G.; Gross, J.

10.1101/336941 — neuroscience — Posted on 2019-01-16

1708 Oxytocin reduces top-down control of attention by increasing bottom-up attention allocation to social but not non-social stimuli

Xu, X.; Li, J.; Chen, Z.; Kendrick, K.; Becker, B.

10.1101/519918 — neuroscience — Posted on 2019-01-16

1709 Shedding light on biogas: a transparent reactor triggers the development of a biofilm dominated by Rhodopseudomonas faecalis that holds potential for improved biogas production

Abendroth, C.; Latorre-Perez, A.; Porcar, M.; Simeonov, C.; Luschnig, O.; Vilanova, C.; Pascual, J.

10.1101/521435 — microbiology — Posted on 2019-01-16

1710 Killer whale genomes reveal a complex history of recurrent admixture and vicariance

Foote, A. D.; Martin, M.; Louis, M.; Pacheco, G.; Robertson, K.; Sinding, M.-H.; Amaral, A.; Baird, R.; Baker, S.; Ballance, L.; Barlow, J.; Brownlow, A.; Collins, T.; Constantine, R.; Dabin, W.; Dalla Rosa, L.; Davison, N.; Durban, J.; Esteban, R.; Ferguson, S.; Gerodette, T.; Guinet, C.; Hanson, B.; Hoggard, W.; Matthews, C.; Samarra, F.; de Stephanis, R.; Tavares, S.; Tixier, P.; Totterdell, J.; Wade, P.; Gilbert, T.; Wolf, J.; Morin, P.

10.1101/520718 — evolutionary biology — Posted on 2019-01-16

1711 Computational deconvolution of gene expression in leukemic cell hierarchies

Järvstrat, L.; Ajore, R.; Wihlborg, A.-K.; Gullberg, U.; Nilsson, B.

10.1101/521864 — bioinformatics — Posted on 2019-01-16

1712 Fibril formation rewires interactome of the Alzheimer protein Tau by π-stacking

Ferrari, L.; Stucci, R.; Konstantoulea, A.; van de Kamp, G.; Kos, R.; Geerts, W. J. C.; Forster, F. G.; Altelaar, M.; Hoogenraad, C.; Rudiger, S. G. D.

10.1101/522284 — biochemistry — Posted on 2019-01-16

1713 Homology-directed repair using transient CRISPR/Cpf1-geminiviral replicon in tomato

Vu, T. V.; Sivankalyani, V.; Kim, E.-J.; Tran, M. T.; Kim, J.; Sung, Y. W.; Doan, D. T. H.; Kim, J.-Y.

10.1101/521419 — molecular biology — Posted on 2019-01-16

1714 High-quality genome assembly and high-density genetic map of asparagus bean

Xia, Q.; Zhang, R.; Ni, X.; Pan, L.; Wang, Y.; Dong, X.; Gao, Y.; Zhang, Z.; Kui, L.; Li, Y.; Wang, W.; Yang, H.; Chen, C.; Miao, J.; Chen, W.; Dong, Y.

10.1101/521179 — genomics — Posted on 2019-01-16

1715 Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells

Broughton, K.; Korski, K.; Echeagaray, O.; Adamson, R.; Dembitsky, W.; Lu, Z.; Schaefer, E.; Sussman, M.

10.1101/521732 — cell biology — Posted on 2019-01-16

1716 Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion

Popa, S.; Villeneuve, J.; Stewart, S.; Perez Garcia, E.; Petrunkina Harrison, A.; Moreau, K.

10.1101/522334 — cell biology — Posted on 2019-01-16

1717 SAMHD1 regulates human papillomavirus 16 induced cell proliferation and viral replication during differentiation of oral keratinocytes.

Morgan, I. M.; James, C. D.; Prabhakar, A. T.; Evans, M. R.; Bristol, M.; Wang, X.; Zhang, K.; Li, R.

10.1101/522250 — cancer biology — Posted on 2019-01-16

1718 De Novo Peptide Sequencing Reveals a Vast Cyclopeptidome in Human Gut and Other Environments

Behsaz, B.; Mohimani, H.; Gurevich, A.; Prjibelski, A.; Fisher, M. F.; Smarr, L.; Dorrestein, P. C.; Mylne, J. S.; Pevzner, P. A.

10.1101/521872 — bioinformatics — Posted on 2019-01-16

1719 KASP-Hedgehog: Efficient and routine tool for allele specific primer design using multidisciplinary data types.

Alsamman, A. M.; Abdelsattar, M.; Ibrahim, S. D.; Hamwieh, A.

10.1101/522045 — bioinformatics — Posted on 2019-01-16

1720 Distinguishing biological from technical sources of variation by leveraging multiple methylation datasets

Thompson, M.; Chen, Z. J.; Rahmani, E.; Halperin, E.

10.1101/521146 — bioinformatics — Posted on 2019-01-16

1721 Rapid microbial interaction network inference in microfluidic droplets

Hsu, R. H.; Clark, R. L.; Tan, J. W.; Romero, P. A.; Venturelli, O. S.

10.1101/521823 — systems biology — Posted on 2019-01-16

1722 The self as a generative, teleological, and subjective prior: Mutually-modulated temporal agency

Asai, T.; Imaizumi, S.; Imamizu, H.

10.1101/519934 — neuroscience — Posted on 2019-01-16

1723 Retapamulin-assisted ribosome profiling reveals the alternative bacterial proteome

Meydan, S.; Marks, J.; Klepacki, D.; Sharma, V.; Baranov, P. V.; Firth, A. E.; Margus, T.; Kefi, A.; Vazquez-Laslop, N.; Mankin, A. S.

10.1101/520783 — molecular biology — Posted on 2019-01-16

1724 Alveolar macrophages up-regulate a non-classical innate response to Mycobacterium tuberculosis infection in vivo

Rothchild, A. C.; Olson, G. S.; Nemeth, J.; Amon, L. M.; Mai, D.; Gold, E. S.; Diercks, A. H.; Aderem, A.

10.1101/520791 — immunology — Posted on 2019-01-16

1725 Mesenchymal stem cells (MSCs) offer a drug tolerant and immune-privileged niche to Mycobacterium tuberculosis

Jain, N.; Kalam, H.; Singh, L.; Sharma, V.; Kedia, S.; Das, P.; Ahuja, V.; Kumar, D.

10.1101/521609 — immunology — Posted on 2019-01-16

1726 High-throughput allelic expression imbalance analyses identify candidate breast cancer risk genes

Moradi Marjaneh, M.; Sivakumaran, H.; Hillman, K.; Kaufmann, S.; Hussein, N.; Lima, L.; Ham, S.; Kar, S.; Beesley, J.; Fachal, L.; Easton, D.; Dunning, A.; Moller, A.; Chenevix-Trench, G.; Edwards, S.; French, J.

10.1101/521013 — genetics — Posted on 2019-01-16

1727 A high throughput deep amplicon sequencing method to show the emergence and spread of Calicophoron daubneyi in United Kingdom cattle herds.

Sargison, N. D.; Shahzad, K.; Mazeri, S.; Chaudhry, U.

10.1101/521229 — evolutionary biology — Posted on 2019-01-16

1728 Tetraploidy in rodent cardiac stem cells confers enhanced biological properties

Broughton, K.; Khieu, T.; Nguyen, N.; Rosa, M.; Mohsin, S.; Quijada, P.; Wang, J.; Echeagaray, O.; Kubli, D.; Kim, T.; Firouzi, F.; Monsanto, M.; Gude, N.; Adamson, R.; Dembitsky, W.; Davis, M.; Sussman, M.

10.1101/521716 — cell biology — Posted on 2019-01-16

1729 GuiltyTargets: Prioritization of Novel Therapeutic Targets with Deep Network Representation Learning

Muslu, O.; Hoyt, C. T.; Hofmann-Apitius, M.; Froehlich, H.

10.1101/521161 — bioinformatics — Posted on 2019-01-16

1730 Probabilistic cell type assignment of single-cell transcriptomic data reveals spatiotemporal microenvironment dynamics in human cancers

Zhang, A. W.; O'Flanagan, C.; Chavez, E.; Lim, J. L.; McPherson, A.; Wiens, M.; Walters, P.; Chan, T.; Hewitson, B.; Lai, D.; Mottok, A.; Sarkozy, C.; Chong, L.; Aoki, T.; Wang, X.; Weng, A. P.; McAlpine, J. N.; Aparicio, S.; Steidl, C.; Campbell, K. R.; Shah, S. P.

10.1101/521914 — bioinformatics — Posted on 2019-01-16

1731 Tumor Copy Number Deconvolution Integrating Bulk and Single-Cell Sequencing Data

Lei, H.; Lyu, B.; Gertz, E. M.; Schaeffer, A. A.; Shi, X.; Wu, K.; Li, G.; Xu, L.; Hu, Y.; Dean, M.; Schwartz, R.

10.1101/519892 — bioinformatics — Posted on 2019-01-16

1732 Assessing the performance of different approaches for functional and taxonomic annotation of metagenomes

Tamames, J.; Cobo-Simon, M.; Puente-Sanchez, F.

10.1101/522292 — bioinformatics — Posted on 2019-01-16

1733 A widespread Xrn1-resistant RNA motif composed of two short hairpins

Dilweg, I. W.; Gultyaev, A. P.; Olsthoorn, R.

10.1101/522318 — biochemistry — Posted on 2019-01-16

1734 Chromatin interactome mapping at 139 independent breast cancer risk signals

Beesley, J.; Sivakumaran, H.; Moradi Marjaneh, M.; Lima, L.; Hillman, K.; Kaufmann, S.; Tuano, N.; Hussein, N.; Ham, S.; Mukhopadhyay, P.; Kazakoff, S.; Lee, J.; Michailidou, K.; Barnes, D.; Antoniou, A.; Fachal, L.; Dunning, A.; Easton, D.; Waddell, N.; Rosenbluh, J.; Moller, A.; Chenevix-Trench, G.; French, J.; Edwards, S.

10.1101/520916 — molecular biology — Posted on 2019-01-16

1735 Draft Genome Sequence and intraspecific diversification of the wild crop relative Brassica cretica Lam. using demographic model selection

Kioukis, A.; Michalopoulou, V. A.; Briers, L.; Pirintsos, S.; Studholme, D. J.; Pavlidis, P.; Sarris, P. F.

10.1101/521138 — genomics — Posted on 2019-01-16

1736 Macroevolution of dimensionless life history metrics in tetrapods

Babich Morrow, C.; Kerkhoff, A. J.; Ernest, S. K. M.

10.1101/520361 — evolutionary biology — Posted on 2019-01-16

1737 Stridulations of Melolontha spp. larvae open up new possibilities for species-specific pest monitoring in soils

Goerres, C.-M.; Chesmore, D.

10.1101/520734 — ecology — Posted on 2019-01-16

1738 Positional information encoded in the dynamic differences between neighbouring oscillators during vertebrate segmentation.

Boareto, M.; Tomka, T.; Iber, D.

10.1101/286328 — developmental biology — Posted on 2019-01-16

1739 Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology

Cellerino, A.; Dolfi, L.; Ripa, R.; Antebi, A.; Valenzano, D. R.

10.1101/522417 — developmental biology — Posted on 2019-01-16

1740 Biobtree: A tool to search, map and visualize bioinformatics identifiers and special keywords

Gur, T.

10.1101/520841 — bioinformatics — Posted on 2019-01-16

1741 Dean flow assisted single cell and bead encapsulation for high performance single cell expression profiling

Li, L.; Wu, P.; Luo, Z.; Wang, L.; Ding, W.; Wu, T.; Chen, J.; He, J.; Chen, Y.; Li, G.; Li, Z.; He, L.

10.1101/520858 — bioengineering — Posted on 2019-01-16

1742 Connecting micro and macroevolution using genetic incompatibilities and natural selection on additive genetic variance

Walter, G. M.; Aguirre, J. D.; Wilkinson, M. J.; Richards, T. J.; Blows, M. W.; Ortiz-Barrientos, D.

10.1101/520809 — evolutionary biology — Posted on 2019-01-16

1743 Mature sperm small RNA profile in the sparrow: implications for transgenerational effects of age on fitness

Matsushima, W.; Brink, K.; Schroeder, J.; Miska, E. A.; Gapp, K.

10.1101/520759 — developmental biology — Posted on 2019-01-16

1744 Crop residues in wheat-oilseed rape rotation system: a pivotal, shifting platform for microbial meetings

Kerdraon, L.; Balesdent, M.-H.; Barret, M.; Laval, V.; Suffert, F.

10.1101/456178 — microbiology — Posted on 2019-01-16

1745 PBMC Treatment Significantly Changes Gene Expression Regulation in Horses

Mason, V. C.; Leeb, T.; Gerber, V.

10.1101/519769 — genomics — Posted on 2019-01-16

1746 Molecular mechanism of TRPV2 channel modulation by cannabidiol

Pumroy, R. A.; Samanta, A.; Liu, Y.; Hughes, T. E. T.; Zhao, S.; Yudin, Y.; Huynh, K. W.; Zhou, Z. H.; Rohacs, T.; Han, S.; Moiseenkova-Bell, V. Y.

10.1101/521880 — biophysics — Posted on 2019-01-16

1747 RNA design movesets and strategies from an Internet-scale videogame

Koodli, R.; Keep, B.; Coppess, K. R.; Portela, F.; Eterna Players, ; Das, R.

10.1101/326736 — bioinformatics — Posted on 2019-01-15

1748 Highly Specific Enrichment of Rare Nucleic Acids using Thermus Thermophilus Argonaute

Song, J.; Hegge, J. W.; Mauk, M. G.; Chen, J.; Bhagwat, N.; Till, J. E.; Azink, L. T.; Peng, J.; Sen, M.; Mays, J.; Carpenter, E.; Oost, J. v. d.; Bau, H. H.

10.1101/491738 — molecular biology — Posted on 2019-01-15

1749 The effect of stride length on lower extremity joint kinetics at various gait speeds

McGrath, R. L.; Ziegler, M. L.; Pires-Fernandes, M.; Knarr, B. A.; Higginson, J. S.; Sergi, F.

10.1101/363788 — bioengineering — Posted on 2019-01-15

1750 Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals

Ulyanova, A. V.; Cottone, C.; Adam, C. D.; Gagnon, K. G.; Cullen, D. K.; Holtzman, T.; Jameison, B.; Koch, P. F.; Chen, H. I.; Johnson, V. E.; Wolf, J. A.

10.1101/400812 — neuroscience — Posted on 2019-01-15

1751 Quantifying individual differences in brain morphometry underlying symptom severity in Autism Spectrum Disorders

Pua, E. P.; Ball, G.; Adamson, C.; Bowden, S.; Seal, M.

10.1101/430355 — neuroscience — Posted on 2019-01-15

1752 Pathogen Detection and Microbiome Analysis of Infected Wheat Using a Portable DNA Sequencer

Hu, Y.; Green, G.; Milgate, A.; Stone, E.; Rathjen, J.; Schwessinger, B.

10.1101/429878 — plant biology — Posted on 2019-01-15

1753 Identifying Changepoints in Biomarkers During the Preclinical Phase of AD

Younes, L.; Albert, M.; Moghekar, A.; Soldan, A.; Pettigrew, C.; Miller, M.

10.1101/508820 — neuroscience — Posted on 2019-01-15

1754 Most of transcriptional alterations in glioma result from DNA-methylation independent mechanisms

Arnaud, P.; Court, F.; Le Boiteux, E.; Fogli, A.; Müller-Barthelemy, M.; Vaurs-Barriere, C.; Chautard, E.; Pereira, B.; Biau, J.; Kemeny, J.-L.; Khalil, T.; Karayan-Tapon, L.; Verrelle, P.

10.1101/516997 — molecular biology — Posted on 2019-01-15

1755 Comparative genomics analysis reveals high levels of differential DNA transposition among primates

Tang, W.; Liang, P.

10.1101/520387 — evolutionary biology — Posted on 2019-01-15

1756 Post exam item analysis: Implication for intervention

Tsegaye, K. N. N.

10.1101/510081 — scientific communication and education — Posted on 2019-01-15

1757 Interaction of taste and place coding in the hippocampus

Herzog, L. E.; Pascual, L. M.; Scott, S. J.; Mathieson, E. R.; Katz, D. B.; Jadhav, S. P.

10.1101/431353 — neuroscience — Posted on 2019-01-15

1758 GRID - Genomics of Rare Immune Disorders: a highly sensitive and specific diagnostic gene panel for patients with primary immunodeficiencies

Simeoni, I.; Shamardina, O.; Deevi, S. V.; Thomas, M.; Megy, K.; Staples, E.; Whitehorn, D.; Duarte, D.; Mapeta, R.; Ouwehand, W. H.; Penkett, C. J.; Rayner-Matthews, P.; Stark, H.; Stephens, J. C.; Stirrups, K. E.; Turro, E.; NIHR BioResource, ; Thrasher, A.; Kuijpers, T. W.; Smith, K. G.; Savic, S.; Burns, S. O.; Thaventhiran, J. E.; Lango Allen, H.

10.1101/431544 — genomics — Posted on 2019-01-15

1759 Cell division history determines hematopoietic stem cell potency

Arai, F.; Stumpf, P. S.; Ikushima, Y. M.; Hosokawa, K.; Roch, A.; Lutolf, M. P.; Suda, T.; MacArthur, B. D.

10.1101/503813 — cell biology — Posted on 2019-01-15

1760 A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin

Santos, S. M.; Hartman, J. L.

10.1101/517490 — systems biology — Posted on 2019-01-15

1761 NOTCH assembles a transcriptional repressive complex containing NuRD and PRC1 to repress genes involved in cell proliferation and differentiation.

Doyen, C. M.; Depierre, D.; Yatim, A.; Heurteau, A.; Lelievre, J. D.; Levy, Y.; Cuvier, O.; Benkirane, M.

10.1101/513549 — molecular biology — Posted on 2019-01-15

1762 Reversing an extracellular electron transfer pathway for electrode-driven NADH generation

Tefft, N. M.; TerAvest, M. A.

10.1101/476481 — synthetic biology — Posted on 2019-01-15

1763 Locations in the Neocortex: A Theory of Sensorimotor Object Recognition Using Cortical Grid Cells

Lewis, M.; Purdy, S.; Ahmad, S.; Hawkins, J.

10.1101/436352 — neuroscience — Posted on 2019-01-15

1764 The future of a partially effective HIV vaccine: assessing limitations at the population level

Selinger, C.; Dimitrov, D. T.; Welkhoff, P.; Bershteyn, A.

10.1101/509828 — epidemiology — Posted on 2019-01-15

1765 Immunofluorescence staining protocol for STED nanoscopy of Plasmodium-infected red blood cells

Mehnert, A.-K.; Simon, C. S.; Guizetti, J.

10.1101/416776 — cell biology — Posted on 2019-01-15

1766 Ultra-high throughput multiplexing and sequencing of >500 bp amplicon regions on the Illumina HiSeq 2500 platform

Holm, J. B.; Humphrys, M.; Robinson, C. K.; Settles, M. L.; Ott, S.; Fu, L.; Yang, H.; Gajer, P.; He, X.; McComb, E. J.; Gravitt, P.; Ghanem, K. G.; Brotman, R. M.; Ravel, J.

10.1101/417618 — microbiology — Posted on 2019-01-15

1767 Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA

Sachdev, R.; Hondele, M.; Linsenmeier, M.; Vallotton, P.; Mugler, C. F.; Arosio, P.; Weis, K.

10.1101/402404 — biochemistry — Posted on 2019-01-15

1768 Molecular noise of innate immunity shapes bacteria-phage ecologies

Ruess, J.; Pleska, M.; Guet, C.; Tkacik, G.

10.1101/399527 — biophysics — Posted on 2019-01-15

1769 PI31 is an adaptor protein for proteasome transport in axons and required for synaptic development and function

Liu, K.; Jones, S.; Minis, A.; Rodriguez, J.; Molina, H.; Steller, H.

10.1101/364463 — cell biology — Posted on 2019-01-15

1770 MultiPLIER: a transfer learning framework for transcriptomics reveals systemic features of rare disease

Taroni, J. N.; Grayson, P. C.; Hu, Q.; Eddy, S.; Kretzler, M.; Merkel, P. A.; Greene, C. S.

10.1101/395947 — bioinformatics — Posted on 2019-01-15

1771 A neural signature of pattern separation in the monkey hippocampus

Sakon, J. J.; Suzuki, W. A.

10.1101/302505 — neuroscience — Posted on 2019-01-15

1772 Partitioning of microbial function among taxonomic ranks across the tree of life

Royalty, T.; Steen, A. D.

10.1101/520973 — microbiology — Posted on 2019-01-15

1773 Sex-specific co-expression networks and sex-biased gene expression in the salmonid Brook Charr Salvelinus fontinalis

Sutherland, B. J. G.; Prokkola, J. M.; Audet, C.; Bernatchez, L.

10.1101/305680 — genomics — Posted on 2019-01-15

1774 Myopic control of neural dynamics

Hocker, D.; Park, I. M.

10.1101/241299 — neuroscience — Posted on 2019-01-15

1775 Evolution of the D. melanogaster chromatin landscape and its associated proteins

Parey, E.; Crombach, A.

10.1101/284828 — evolutionary biology — Posted on 2019-01-15

1776 Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila

Gultekin, Y.; Steller, H.

10.1101/296830 — developmental biology — Posted on 2019-01-15

1777 3’UTR cleavage of transcripts localized in axons of sympathetic neurons

Andreassi, C.; Luisier, R.; Crerar, H.; Franke, S.; Luscombe, N. M.; Cuda, G.; Gaspari, M.; Riccio, A.

10.1101/170100 — neuroscience — Posted on 2019-01-15

1778 Dissociable neural information dynamics of perceptual integration and differentiation during bistable perception

Canales-Johnson, A.; Billig, A.; Olivares, F.; Gonzalez, A.; Garcia, M. d. C.; Silva, W.; Ciraolo, C.; Vaucheret, E.; Mikulan, E.; Ibanez, A.; Noreika, V.; Chennu, S.; Bekinschtein, T.

10.1101/133801 — neuroscience — Posted on 2019-01-15

1779 Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

Fachal, L.; Aschard, H.; Beesley, J.; Barnes, D.; Allen, J.; Kar, S.; Pooley, K.; Dennis, J.; Michailidou, K.; Turman, C.; Soucy, P.; Lemacon, A.; Lush, M.; Tyrer, J.; Ghoussaini, M.; Moradi Marjaneh, M.; Jiang, X.; Agata, S.; Aittomaki, K.; Alonso, M. R.; Andrulis, I.; Anton-Culver, H.; Antonenkova, N.; Arason, A.; Arndt, V.; Aronson, K.; Arun, B.; Auber, B.; Auer, P.; Azzollini, J.; Balmana, J.; Barkardottir, R.; Barrowdale, D.; Beeghly-Fadiel, A.; Benitez, J.; Bermisheva, M.; Bialkowska, K.; Blanco, A.; Blomqvist, C.; Blot, W.; Bogdanova, N.; Bojesen, S.; Bolla, M.; Bonanni, B.; Borg, A.; B

10.1101/521054 — genetics — Posted on 2019-01-15

1780 PIK3CA in KrasG12D/Trp53R172H Tumor Cells Promotes Immune Evasion by Limiting Infiltration of T Cells in a Model of Pancreatic Cancer

Sivaram, N.; McLaughlin, P. A.; Han, H. V.; Petrenko, O.; Jiang, Y.-P.; Ballou, L. M.; Pham, K.; Liu, C.; Van der Velden, A. W. M.; Lin, R. Z.

10.1101/521831 — cancer biology — Posted on 2019-01-15

1781 Nitrative signaling into cardiac lactate dehydrogenase Trp324 modulates active site loop mobility and activity under metabolic stress

Nogales, C.; Frihoff, J.; Thoenges, D.; Sessions, R. B.; Sickmann, A.; Nedvetskaya, T.; Ibarra-Alvarado, C.; Schmitz, V.; Rosen, P.; Goedecke, A.; Jovanovic, A.; Perlman, D. H.; Klinke, A.; Baldus, S.; Casas, A. I.; Bai, P.; Szabo, C.; Feelisch, M.; Schmidt, H. H. H. W.

10.1101/348789 — biochemistry — Posted on 2019-01-15

1782 BEHST: genomic set enrichment analysis enhanced through integration of chromatin long-range interactions

Chicco, D.; Bi, H. S.; Reimand, J.; Hoffman, M. M.

10.1101/168427 — bioinformatics — Posted on 2019-01-15

1783 The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses

Schmider, A. B.; Vaught, M.; Bauer, N. C.; Elliott, H. L.; Godin, M. D.; Ellis, G. E.; Nigrovic, P.; Soberman, R. J.

10.1101/521625 — cell biology — Posted on 2019-01-15

1784 The Drosophila ERG channel seizure plays a role in the neuronal homeostatic stress response

Hill, A.; Jain, P.; Ben-Shahar, Y.

10.1101/521005 — neuroscience — Posted on 2019-01-15

1785 Transient compartmentalization dynamics in the presence of mutations and noise

Blokhuis, A.; Nghe, P.; Peliti, L.; Lacoste, D.

10.1101/521211 — biophysics — Posted on 2019-01-15

1786 ICA512 RESP18 homology domain is a protein condensing factor and insulin fibrillation inhibitor

Toledo, P. L.; Torkko, J. M.; Müller, A.; Wegbrod, C.; Sönmez, A.; Solimena, M.; Ermacora, M. R.

10.1101/521351 — biophysics — Posted on 2019-01-15

1787 SGK1.1 activation causes early seizure termination via effects on M-current

Armas-Capote, N.; Maglio, L. E.; Perez-Atencio, L.; Martin-Batista, E.; Reboreda, A.; Barios, J. A.; Hernandez, G.; Alvarez de la Rosa, D.; Lamas, J. A.; Barril, L. C.; Giraldez, T.

10.1101/520775 — neuroscience — Posted on 2019-01-15

1788 NMDAR-activated PP1 dephosphorylates GluN2B to modulate NMDAR plasticity.

Chiu, A. M.; Wang, J.; Fiske, M. P.; Hubalkova, P.; Barse, L.; Gray, J. A.; Sanz-Clemente, A.

10.1101/520882 — neuroscience — Posted on 2019-01-15

1789 Multiple phase-variable mechanisms, including capsular polysaccharides, modify bacteriophage susceptibility in Bacteroides thetaiotaomicron

Porter, N. T.; Hryckowian, A. J.; Merrill, B. D.; Gardner, J. O.; Singh, S.; Sonnenburg, J. L.; Martens, E. C.

10.1101/521070 — microbiology — Posted on 2019-01-15

1790 Autophagy regulates the localization and degradation of p16INK4a

Coryell, P. R.; Goraya, S. K.; Griffin, K. A.; Redick, M. A.; Sisk, S. R.; Purvis, J. E.

10.1101/521682 — cell biology — Posted on 2019-01-15

1791 Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance

Henson, M. A.; Orazi, G.; Phalak, P.; O'Toole, G.

10.1101/520619 — microbiology — Posted on 2019-01-15

1792 Meiotic viral attenuation through an ancestral apoptotic pathway

Meneghini, M. D.; Gao, J.; Chau, S.; Chowdhury, F.; Zhou, T.; Hossain, S.; Mcquibban, A.

10.1101/521237 — genetics — Posted on 2019-01-15

1793 Hip circumduction is not a compensation for reduced knee flexion angle during gait

Akbas, T.; Prajapati, S.; Ziemnicki, D.; Tamma, P.; Gross, S.; Sulzer, J.

10.1101/520684 — bioengineering — Posted on 2019-01-15

1794 Stimulation of Gαq Promotes Stress Granule Formation

Qifti, A.; Jackson, L.; Singla, A.; Garwain, O.; Scarlata, S.

10.1101/521369 — biochemistry — Posted on 2019-01-15

1795 Constitutive Androstane Receptor contributes towards increased drug clearance in cholestasis

Mathur, B.; Arif, W.; Patton, M.; Faiyaz, R.; Kalsotra, A.; Wheatley, A. M.; Anakk, S.

10.1101/520692 — physiology — Posted on 2019-01-15

1796 Mechanism of microtubule plus-end tracking by the plant-specific SPR1 protein and its development as a versatile plus-end marker

Balkunde, R. S.; Foroughi, L.; Ewan, E.; Emenecker, R.; Cavalli, V.; Dixit, R.

10.1101/521047 — cell biology — Posted on 2019-01-15

1797 HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness Phenotype in Medulloblastoma

Jaeger, M. d. C.; Ghisleni, E. C.; Cardoso, P. S.; Siniglaglia, M.; Falcon, T.; Brunetto, A. T.; Brunetto, A. L.; de Farias, C. B.; Taylor, M. D.; Nor, C.; Ramaswamy, V.; Roesler, R.

10.1101/521393 — cancer biology — Posted on 2019-01-15

1798 Diffusion Tensor Imaging connectivity analysis: detecting structural alterations and their underlying substrates for Optic Ataxia in correlations with \"How\" stream Visual Pathways

Elumalai, G.; Maiti, P.; Vinodhanand, G.; Camoya Brown, V. L.; Venkata Ghanta, N. A. S.; Yadav Kurra, V. H. K.

10.1101/520635 — neuroscience — Posted on 2019-01-15

1799 A role for gene-environment interactions in Autism Spectrum Disorder is suggested by variants in genes regulating exposure to environmental factors

Santos, J. X.; Rasga, C.; Marques, A. R.; Martiniano, H. F. M. C.; Asif, M.; Vilela, J.; Oliveira, G.; Vicente, A. M.

10.1101/520544 — genetics — Posted on 2019-01-15

1800 Adapting the ELEAT: Early Life Exposure Assessment Tool) to Portugal - a pilot study to tackle gene-environment interactions in Autism Spectrum Disorder

Rasga, C.; Lopes, A. L.; Santos, J. X.; Marques, A. R.; Vilela, J.; Asif, M.; Oliveira, G.; Bennett, D.; Walker, C.; Schmid, R.; Vicente, A. M.

10.1101/520593 — developmental biology — Posted on 2019-01-15

1801 Assessing the remarkable morphological diversity and transcriptomic basis of leaf shape in Ipomoea batatas (sweetpotato)

Gupta, S.; Rosenthal, D. M.; Stinchcombe, J. R.; Baucom, R. S.

10.1101/520650 — plant biology — Posted on 2019-01-15

1802 Signatures of replication, recombination and sex in the spectrum of rare variants on the human X chromosome and autosomes

Agarwal, I.; Przeworski, M.

10.1101/519421 — genomics — Posted on 2019-01-15

1803 β-catenin has an ancestral role in cell fate specification but not cell adhesion

Salinas-Saavedra, M.; Wikramanayake, A.; Martindale, M. Q.

10.1101/520957 — developmental biology — Posted on 2019-01-15

1804 The emergence of integrated information, complexity, andconsciousness at criticality

Khajehabdollahi, S.; Abeyasinghe, P.; Owen, A.; Soddu, A.

10.1101/521567 — neuroscience — Posted on 2019-01-15

1805 A new transgenic reporter line reveals Wnt-dependent Snail2 re-expression and cranial neural crest differentiation in Xenopus

Li, J.; Perfetto, M.; Materna, C.; Li, R.; Tran, H. T.; Vleminckx, K.; Duncan, M. K.; Wei, S.

10.1101/520726 — developmental biology — Posted on 2019-01-15

1806 Predicting disease-causing variant combinations

Papadimitriou, S.; Gazzo, A.; Versbraegen, N.; Nachtegael, C.; Aerts, J.; Moreau, Y.; Van Dooren, S.; Nowe, A.; Smits, G.; Lenaerts, T.

10.1101/520353 — bioinformatics — Posted on 2019-01-15

1807 Computation of stationary distributions in stochastic models of cellular processes with molecular memory

Zhang, J.; Zhou, T.

10.1101/521575 — systems biology — Posted on 2019-01-15

1808 Neuropathological validation of the MDS-PSP criteria with PSP and other frontotemporal lobar degeneration

Gazzina, S.; Respondek, G.; Compta, Y.; Allinson, K. S.; Spillantini, M. G.; Molina-Porcel, L.; Guasp-Verdaguer, M.; Moftakhar, S.; Reich, S. G.; Hall, D.; Litvan, I.; Hoeglinger, G.; Rowe, J. B.

10.1101/520510 — neuroscience — Posted on 2019-01-15

1809 Spatial summation of individual cones in human color vision

Schmidt, B.; Boehm, A. E.; Tuten, W. S.; Roorda, A.

10.1101/521492 — neuroscience — Posted on 2019-01-15

1810 Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methods

Cunningham, J. M.; McDonough, S. J.; Bhagwate, A.; Sun, Z.; Wang, C.; Zschunke, M.; Gorman, J. A.; Kopp, K. J.

10.1101/521534 — molecular biology — Posted on 2019-01-15

1811 Locating a transgene integration site by nanopore sequencing

Page, D. C.; Nicholls, P.; Bellott, D. W.; Cho, T.-J.; Pyntikova, T.

10.1101/520627 — genomics — Posted on 2019-01-15

1812 Development of a sequence-based reference physical map of pea (Pisum sativum L.)

Gali, K. K.; Tar'an, B.; Madoui, M.-A.; van der Vossen, E.; van Oeveren, J.; Labadie, K.; Berges, H.; Bendahmane, A.; Lachagari, R. V. B.; Burstin, J.; Warkentin, T. D.

10.1101/518563 — genomics — Posted on 2019-01-15

1813 Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas

Perez-Garcia, V. M.; Ayala-Hernandez, L. E.; Belmonte-Beitia, J.; Schucht, P.; Murek, M.; Raabe, A.; Sepulveda, J.

10.1101/521559 — cancer biology — Posted on 2019-01-15

1814 Geometric control of frequency modulation of cAMP oscillations due to Ca2+-bursts in dendritic spines

Ohadi, D.; Rangamani, P.

10.1101/520643 — biophysics — Posted on 2019-01-15

1815 Chromokinesins NOD and KID Use Distinct ATPase Mechanisms and Microtubule Interactions to Perform a Similar Function

Walker, B. C.; Tempel, W.; Zhu, H.; Park, H.; Cochran, J. C.

10.1101/520460 — biochemistry — Posted on 2019-01-15

1816 Circular inference in bistable perception

Leptourgos, P.; Notredame, C.-E.; Eck, M.; Jardri, R.; Deneve, S.

10.1101/521195 — neuroscience — Posted on 2019-01-15

1817 Involvement of gestational weight and body composition on autonomic recovery following aerobic exercise in children: a prospective, observational and analytical study

Martinez Spada, J. E.; Oliveira, F. R.; Garner, D. M.; Valenti, V. E.; Juliana Edwiges Martinez Spada Fernando R. Oliveira David M. Garner Vitor E. Valent,

10.1101/521500 — neuroscience — Posted on 2019-01-15

1818 Binding of Filamentous Actin to CaMKII as a Potential Mechanism for the Regulation of Bidirectional Synaptic Plasticity by betaCaMKII in Cerebellar Purkinje Cells

Pinto, T.; Schilstra, M. J.; Roque, A. C.; Steuber, V.

10.1101/521542 — neuroscience — Posted on 2019-01-15

1819 Identification of Physiological Response Functions to Correct for Fluctuations in Resting-State fMRI related to Heart Rate and Respiration

Kassinopoulos, M.; Mitsis, G. D.

10.1101/512855 — neuroscience — Posted on 2019-01-15

1820 Regulation of Parent-of-Origin Allelic Expression in Arabidopsis thaliana endosperm

Hornslien, K. S.; Miller, J. R.; Grini, P. E.

10.1101/521583 — genetics — Posted on 2019-01-15

1821 Cdk1 in germline and the dose of somatic EGFR signaling determine the rate of transit amplification

Gadre, P. S.; Chatterjee, S.; Varshney, B.; Joshi, C. C.; Gupta, S.; Nitsure, N.; Ray, K.

10.1101/521336 — developmental biology — Posted on 2019-01-15

1822 Nucleus accumbens cholinergic interneurons oppose cue-motivated behavior

Collins, A. L.; Aitken, T. J.; Huang, I.-W.; Shieh, C.; Greenfield, V.; Monbouquette, H. G.; Ostlund, S. B.; Wassum, K. M.

10.1101/520817 — neuroscience — Posted on 2019-01-15

1823 Coherent coding of spatial position mediated by theta oscillations in hippocampus and prefrontal cortex

Zielinski, M. C.; Shin, J. D.; Jadhav, S. P.

10.1101/520585 — neuroscience — Posted on 2019-01-15

1824 Why does the zebrafish cloche mutant develop lens cataract?

Posner, M.; McDonald, M. S.; Murray, K. L.; Kiss, A. J.

10.1101/521526 — developmental biology — Posted on 2019-01-15

1825 Quantitative Analysis of Global Protein Stability Rates in Tissues

McClatchy, D. B.; Gao, Y.; Lavalle-Adam, M.; Yates, J. R.

10.1101/520494 — cell biology — Posted on 2019-01-15

1826 Personality homophily affects male social bonding in wild Assamese macaques (Macaca assamensis)

Ebenau, A.; von Borell, C.; Penke, L.; Ostner, J.; Schuelke, O.

10.1101/520064 — animal behavior and cognition — Posted on 2019-01-15

1827 A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin

Santos, S. M.; Hartman, J. L.

10.1101/517490 — systems biology — Posted on 2019-01-15

1828 Chromosome-level assembly of the common lizard (Zootoca vivipara) genome

Yurchenko, A. A.; Recknagel, H.; Elmer, K. R.

10.1101/520528 — genomics — Posted on 2019-01-15

1829 Spatial synchrony in vegetation response

Weissmann, H.; Michael, Y.; Shnerb, N. M.

10.1101/520296 — ecology — Posted on 2019-01-15

1830 Analytical expressions and physical principles for single-cell mRNA distributions of the lac operon of Escherichia coli

Choudhary, K.; Narang, A.

10.1101/520478 — biophysics — Posted on 2019-01-15

1831 Grass silica mineralizer (GSM1) protein precipitates silica in sorghum silica cells

Kumar, S.; Adiram-Filiba, N.; Blum, S.; Sanchez-Lopez, J. A.; Tzfadia, O.; Omid, A.; Volpin, H.; Heifetz, Y.; Goobes, G.; Elbaum, R.

10.1101/518332 — plant biology — Posted on 2019-01-15

1832 The relationship between spatial configuration and functional connectivity of brain regions revisited

Bijsterbosch, J. D.; Beckmann, C. F.; Woolrich, M. W.; Smith, S. M.; Harrison, S. J.

10.1101/520502 — neuroscience — Posted on 2019-01-15

1833 Genetic Variability and Correlation Coefficients of Major Traits in Early Maturing Rice under Rainfed Lowland Environments of Nepal

Tiwari, D. N.; Tripathi, S. R.; Tripathi, M. P.; Khatri, N.; Bastola, B. R.

10.1101/520338 — genetics — Posted on 2019-01-15

1834 Inferring wildlife poaching in Southeast Asia with multispecies dynamic site-occupancy models

Marescot, L.; Lyet, A.; Singh, R.; Carter, N.; Gimenez, O.

10.1101/520114 — ecology — Posted on 2019-01-15

1835 Biotic interactions and climate in species distribution modelling

Bebber, D.; Gurr, S.

10.1101/520320 — ecology — Posted on 2019-01-15

1836 The Human Default Consciousness and its Disruption: Insights from an EEG Study of Buddhist Jhana Meditation

Dennison, P.

10.1101/407544 — neuroscience — Posted on 2019-01-15

1837 Plasticity versus stability across the human cortical visual connectome

Haak, K. V.; Beckmann, C. F.

10.1101/520395 — neuroscience — Posted on 2019-01-15

1838 Arp2/3 complex-driven spatial patterning of the B cell receptor (BCR) enhances immune synapse formation, BCR signaling, and cell activation

Bolger-Munro, M.; Choi, K.; Scurll, J.; Abraham, L.; Chappell, R.; Sheen, D.; Dang-Lawson, M.; Wu, X.; Priatel, J. J.; Coombs, D.; Hammer, J. A.; Gold, M. R.

10.1101/490698 — immunology — Posted on 2019-01-15

1839 TORC2 Affects Endocytosis through Plasma Membrane Tension

Riggi, M.; Macchione, M.; Matile, S.; Loewith, R.; Roux, A.

10.1101/520551 — cell biology — Posted on 2019-01-15

1840 Genetic Landscape of Electron Transport Chain Complex I Dependency in Acute Myeloid Leukemia

Baccelli, I.; Gareau, Y.; Lehnertz, B.; Gingras, S.; Spinella, J.-F.; Beautrait, A.; Corneau, S.; Mayotte, N.; Boivin, I.; Girard, S.; MacRae, T.; Frechette, M.; Leveille, K.; Krosl, J.; Thiollier, C.; Lavallee, V.; Kanshin, E.; Bertomeu, T.; Coulombe-Huntington, J.; St-Denis, C.; Bordeleau, M.-E.; Boucher, G.; Roux, P. P.; Lemieux, S.; Tyers, M.; Thibault, P.; Hebert, J.; Marinier, A.; Sauvageau, G.

10.1101/513887 — cancer biology — Posted on 2019-01-15

1841 Comparative genomics analysis reveals high levels of differential DNA transposition among primates

Tang, W.; Liang, P.

10.1101/520387 — evolutionary biology — Posted on 2019-01-14

1842 Extracellular electron uptake by two Methanosarcina species

Yee, M. O.; Snoeyenbos-West, O. L. O.; Thamdrup, B.; Ottosen, L. D. M.; Rotaru, A.-E.

10.1101/458091 — microbiology — Posted on 2019-01-14

1843 A Data-Driven Transcriptional Taxonomy of Adipogenic Chemicals to Identify Emerging Metabolic Health Threats

Kim, S.; Reed, E.; Monti, S.; Schlezinger, J.

10.1101/519629 — pharmacology and toxicology — Posted on 2019-01-14

1844 The off-target kinase landscape of clinical PARP inhibitors

Antolin, A. A.; Ameratunga, M.; Banerji, U.; Clarke, P.; Workman, P.; Al-Lazikani, B.

10.1101/520023 — pharmacology and toxicology — Posted on 2019-01-14

1845 The human ventromedial prefrontal cortex: sulcal morphology and its influence on functional organization.

Lopez-Persem, A.; Verhagen, L.; Amiez, C.; Petrides, M.; Sallet, J.

10.1101/417824 — neuroscience — Posted on 2019-01-14

1846 Dynamic properties of internal noise probed by modulating binocular rivalry

Baker, D. H.; Richard, B.

10.1101/480988 — neuroscience — Posted on 2019-01-14

1847 Inhibition and excitation shape activity selection: effect of oscillations in a decision-making circuit

Bose, T.; Reina, A.; Marshall, J. A. R.

10.1101/373282 — neuroscience — Posted on 2019-01-14

1848 Natural strain variation reveals diverse biofilm regulation in squid-colonizing Vibrio fischeri

Rotman, E. R.; Bultman, K. M.; Brooks, J. F.; Gyllborg, M. C.; Burgos, H. L.; Wollenberg, M. S.; Mandel, M. J.

10.1101/471292 — microbiology — Posted on 2019-01-14

1849 Genetic association analyses highlight IL6, ALPL, and NAV1 as three new susceptibility genes underlying calcific aortic valve stenosis

Theriault, S.; Dina, C.; Messika-Zeitoun, D.; Le Scouarnec, S.; Capoulade, R.; Gaudreault, N.; Rigade, S.; Li, Z.; Simonet, F.; Lamontagne, M.; Clavel, M.-A.; Arsenault, B. J.; Boureau, A.-S.; Lecointe, S.; Baron, E.; Bonnaud, S.; Karakachoff, M.; Charpentier, E.; Fellah, I.; Roussel, J.-C.; Verhoye, J. P.; Baufreton, C.; Probst, V.; Roussel, R.; D.E.S.I.R. Study Group, ; Redon, R.; Dagenais, F.; Pibarot, P.; Mathieu, P.; Le Tourneau, T.; Bosse, Y.; Schott, J.-J.

10.1101/515494 — genomics — Posted on 2019-01-14

1850 Fast and flexible linear mixed models for genome-wide genetics

Runcie, D. E.; Crawford, L.

10.1101/373902 — genomics — Posted on 2019-01-14

1851 Nestin in immature embryonic neurons regulates axon growth cone morphology and Sema3a sensitivity

Bott, C. J.; Johnson, C. G.; Yap, C. C.; Dwyer, N. D.; Newell-Litwa, K.; Winckler, B.

10.1101/228296 — cell biology — Posted on 2019-01-14

1852 Eurotium cristatum, a new fungi probiotic from Fuzhuan brick tea, alleviated obesity in mice by modulating gut microbiota

Kang, D.; Su, M.; Duan, Y.; Huang, Y.

10.1101/518068 — microbiology — Posted on 2019-01-14

1853 HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

Asquith, M.; Sternes, P. R.; Costello, M.-E.; Karstens, L.; Diamond, S.; Martin, T. M.; Spector, T. D.; le Cao, K.-A.; Rosenbaum, J. T.; Brown, M. A.

10.1101/517813 — microbiology — Posted on 2019-01-14

1854 Variable costs and benefits of eavesdropping a green leaf volatile on two plant species in a common garden

Freundlich, G. E.; Frost, C.

10.1101/370692 — ecology — Posted on 2019-01-14

1855 Inference of CRISPR Edits from Sanger Trace Data

Hsiau, T.; Conant, D.; Maures, T.; Waite, K.; Yang, J.; Kelso, R.; Holden, K.; Enzmann, B. L.; Stoner, R.

10.1101/251082 — bioinformatics — Posted on 2019-01-14

1856 How exerting control over outcomes affects the neural coding of tasks and outcomes

Wisniewski, D.; Forstmann, B.; Brass, M.

10.1101/375642 — neuroscience — Posted on 2019-01-14

1857 A single microRNA-Hox gene module controls complex movement in morphologically-distinct developmental forms of Drosophila

Issa, R.; Picao-Osorio, J.; Rito, N.; Chiappe, M. E.; Alonso, C. R.

10.1101/511881 — neuroscience — Posted on 2019-01-14

1858 Parkinson’s disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input

Baaske, M. K.; Kormann, E.; Holt, A. B.; Gulberti, A.; McNamara, C. G.; Poetter-Nerger, M.; Westphal, M.; Engel, A. K.; Hamel, W.; Brown, P.; Moll, C. K. E.; Sharott, A.

10.1101/513234 — neuroscience — Posted on 2019-01-14

1859 Shigella flexneri adherence factor expression in in vivo-like conditions

Chanin, R. B.; Nickerson, K. P.; Llanos-Chea, A.; Sistrunk, J. R.; Rasko, D.; Vijaya Kumar, D. K.; De La Parra, J.; Auclair, J.; Ding, J.; Li, K.; Dogiparthi, S.; Kusber, B.; Faherty, C. S.

10.1101/514679 — microbiology — Posted on 2019-01-14

1860 GRID - Genomics of Rare Immune Disorders: a highly sensitive and specific diagnostic gene panel for patients with primary immunodeficiencies

10.1101/431544 — genomics — Posted on 2019-01-14

1861 The Genomic Landscape of Centromeres in Cancers

Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R.

10.1101/505800 — genomics — Posted on 2019-01-14

1862 Serum metabolomics and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) Study

Alonso, A.; Yu, B.; Sun, Y. V.; Chen, L. Y.; Loehr, L. R.; O'Neal, W. T.; Soliman, E. Z.; Boerwinkle, E.

10.1101/368118 — epidemiology — Posted on 2019-01-14

1863 Enabling population assignment from cancer genomes with SNP2pop

Huang, Q.; Baudis, M.

10.1101/368647 — bioinformatics — Posted on 2019-01-14

1864 Cognitive vulnerability to sleep deprivation is robustly associated with two dynamic connectivity states

Teng, J.; Ong, J. L.; Patanaik, A.; Tandi, J.; Zhou, J. H.; Chee, M. W. L.; Lim, J.

10.1101/509745 — neuroscience — Posted on 2019-01-14

1865 Identification of common molecular biomarker signatures in blood and brain of Alzheimers disease

Rahman, M. R.; Islam, T.; Shahjaman, M.; Quinn, J. M. W.; Holsinger, R. M. D.; Moni, M. A.

10.1101/482828 — neuroscience — Posted on 2019-01-14

1866 Rapid bacterial identification by direct PCR amplification of 16S rRNA genes using the MinION™ nanopore sequencer

Kai, S.; Matsuo, Y.; Nakagawa, S.; Kryukov, K.; Matsukawa, S.; Tanaka, H.; Iwai, T.; Imanishi, T.; Hirota, K.

10.1101/435859 — microbiology — Posted on 2019-01-14

1867 Mining ancient microbiomes using selective enrichment of damaged DNA molecules

Weiss, C. L.; Gansauge, M.-T.; Aximu-Petri, A.; Meyer, M.; Burbano, H. A.

10.1101/397927 — genomics — Posted on 2019-01-14

1868 Prediction of Algal Blooms in the Great Lakes through a Convolution Neural Network of Remote Sensing Data

Srinivasan, K.; Duvvur, V.; Duvvur, V.

10.1101/450551 — ecology — Posted on 2019-01-14

1869 Protein Fold Determination by Assembling Extended Super-Secondary Structure Motifs Using Limited NMR Data

Pilla, K. B.

10.1101/509356 — biophysics — Posted on 2019-01-14

1870 Error sensitivity and optimization of steady-state kinetic parameters using multidimensional chemical kinetic analysis

Eskew, J. S.; Connell, C. G.; Cochran, J. C.

10.1101/474171 — biochemistry — Posted on 2019-01-14

1871 Optogenetic entrainment of the septo-hippocampal circuit is state conditional and attenuates spatial accuracy

Mouchati, P. R.; Holmes, G. L.; Kloc, M. L.; Barry, J. M.

10.1101/392050 — neuroscience — Posted on 2019-01-14

1872 Quasi-periodic patterns contribute to functional connectivity in the brain

Abbas, A.; Belloy, M.; Kashyap, A.; Billings, J.; Nezafati, M.; Keilholz, S.

10.1101/323162 — neuroscience — Posted on 2019-01-14

1873 The necessary emergence of structural complexity in self-replicating RNA populations

G. Oliver, C.; Reinharz, V.; Waldispühl, J.

10.1101/218990 — evolutionary biology — Posted on 2019-01-14

1874 Inter-annual variation in seasonal dengue epidemics driven by multiple interacting factors in Guangzhou, China

Oidtman, R. J.; Lai, S.; Huang, Z.; Yang, J.; Siraj, A. S.; Reiner, R. C.; Tatem, A. J.; Perkins, A.; Yu, H.

10.1101/310896 — epidemiology — Posted on 2019-01-14

1875 Locus coeruleus integrity preserves memory performance across the adult life span

Dahl, M. J.; Mather, M.; Duezel, S.; Bodammer, N. C.; Lindenberger, U.; Kuehn, S.; Werkle-Bergner, M.

10.1101/332098 — neuroscience — Posted on 2019-01-14

1876 Electrophysiological correlates of hyperoxia during resting-state EEG in awake human subjects

Vuong, W.; Kizuk, S. A. D.; MacLean, J.; Dickson, C. T.; Mathewson, K.

10.1101/355941 — neuroscience — Posted on 2019-01-14

1877 A pleiotropic chemoreceptor facilitates the coupling of pheromonal signal perception and production

Zelle, K.; Vernier, C.; Liang, X.; Halloran, S.; Millar, J.; Ben-Shahar, Y.

10.1101/124305 — genetics — Posted on 2019-01-14

1878 Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots

Dashti, A.; Shekhar, M.; Ben Hail, D.; Mashayekhi, G.; Schwander, P.; des Georges, A.; Frank, J.; Singharoy, A.; Ourmazd, A.

10.1101/291922 — biophysics — Posted on 2019-01-14

1879 Optimized functional annotation of ChIP-seq data

Khomtchouk, B. B.; Koehler, W. C.; Van Booven, D.; Wahlestedt, C.

10.1101/082347 — bioinformatics — Posted on 2019-01-14

1880 Behavioral repeatability and foraging performance in wild free-flying nectarivorous bats (Glossophaga commissarisi)

Nachev, V.; Winter, Y.

10.1101/309971 — animal behavior and cognition — Posted on 2019-01-14

1881 Transcranial recording of electrophysiological neural activity in the rodent brain in vivo using functional photoacoustic imaging of near-infrared voltage-sensitive dye

Kang, J.; Zhang, H. K.; Kadam, S. D.; Fedorko, J.; Valentine, H.; Malla, A. P.; Yan, P.; Harraz, M. M.; Kang, J. U.; Rahmim, A.; Gjedde, A.; Loew, L. M.; Wong, D. F.; Boctor, E. M.

10.1101/202408 — neuroscience — Posted on 2019-01-14

1882 Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome

Koehler, F.; Bormann, F.; Raddatz, G.; Gutekunst, J.; Musch, T.; Lyko, F.; Rodriguez-Paredes, M.

10.1101/520403 — cell biology — Posted on 2019-01-14

1883 SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

Smeester, B.; Slipek, N.; Pomeroy, E.; Bomberger, H.; Shamsan, G.; Peterson, J.; Crosby, M.; Draper, G.; Becklin, K.; Rahrmann, E.; McCarthy, J.; Odde, D.; Wood, D.; Largaespada, D.; Moriarity, B.

10.1101/520452 — cancer biology — Posted on 2019-01-14

1884 Wingless promotes JNK/MMPs positive feedback loop mediate tumour microtubes expansion, glioma progression and neurodegeneration

Portela, M.; Fahey-Lozano, N.; Casas-Tinto, S.

10.1101/520346 — cancer biology — Posted on 2019-01-14

1885 Discovery of a redox-thiol switch regulating cellular energy metabolism

Gao, X.-H.; Li, L.; Parisien, M.; Mcleod, M.; Wu, J.; Bederman, I.; Gao, Z.; Krokowski, D.; Chirieleison, S. M.; Diatchenko, L.; Abbott, D.; Yee, V.; Hoppel, C.; Kibbey, R.; Holyoak, T.; Willard, B.; Arvan, P.; Hatzoglou, M.

10.1101/520411 — biochemistry — Posted on 2019-01-14

1886 Microtubule bundling by MAP65-1 protects against severing by inhibiting the binding of katanin

Burkart, G.; Dixit, R.

10.1101/520445 — cell biology — Posted on 2019-01-14

1887 Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles

Egbert, J. R.; Fahey, P. G.; Reimer, J.; Owen, C. M.; Evsikov, A. V.; Nikolaev, V. O.; Griesbeck, O.; Ray, R. S.; Tolias, A. S.; Jaffe, L. A.

10.1101/520122 — cell biology — Posted on 2019-01-14

1888 The Caudate Nucleus Undergoes Dramatic and Unique Transcriptional Changes in Human Prodromal Huntington’s Disease Brain

Agus, F.; Crespo, D.; Myers, R. H.; Labadorf, A.

10.1101/520312 — genomics — Posted on 2019-01-14

1889 A hypomorphic allele of telomerase reverse transcriptase uncovers the minimal functional length of telomeres in Arabidopsis.

Watson, J. M.; Trieb, J.; Troestl, M.; Renfrew, K.; Mandakova, T.; Shippen, D. E.; Riha, K.

10.1101/520163 — genetics — Posted on 2019-01-14

1890 Comparative genomics analysis reveals high levels of differential DNA transposition among primates

Tang, W.; Liang, P.

10.1101/520387 — evolutionary biology — Posted on 2019-01-14

1891 Dynamics of transcriptional regulation from total RNA-seq experiments

Furlan, M.; de Pretis, S.; Galeota, E.; Caselle, M.; Pelizzola, M.

10.1101/520155 — systems biology — Posted on 2019-01-14

1892 Exaggerated in vivo IL-17 responses discriminate recall responses in active TB

10.1101/516690 — immunology — Posted on 2019-01-14

1893 Cross-talk of cellulose and mannan perception pathways leads to inhibition of cellulase production in several filamentous fungi

Hassan, L.; Lin, L.; Sorek, H.; Goudoulas, T.; Germann, N.; Tian, C.; Benz, J. P.

10.1101/520130 — genetics — Posted on 2019-01-14

1894 Conscious perception of natural images is constrained by category-related visual features

Lindh, D.; Sligte, I. G.; Assecondi, S.; Shapiro, K. I.; Charest, I.

10.1101/509927 — neuroscience — Posted on 2019-01-14

1895 Sensory-motor brain dynamics reflect architectural affordances

Djebbara, Z.; Fich, L. B.; Petrini, L.; Gramann, K.

10.1101/520080 — neuroscience — Posted on 2019-01-14

1896 Resting multivoxel activity patterns in human visual cortex are linked to patterns evoked by preferred visual stimuli

Kim, D.; Livne, T.; Metcalf, N.; Corbetta, M.; Shulman, G. L.

10.1101/518712 — neuroscience — Posted on 2019-01-14

1897 Alveolar macrophage chromatin is uniquely modified to orchestrate host response to Mycobacterium bovis infection

Hall, T. J.; Vernimmen, D.; Browne, J. A.; Mullen, M. P.; Gordon, S. V.; MacHugh, D. E.; O'Doherty, A. M.

10.1101/520098 — genomics — Posted on 2019-01-14

1898 Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy

Ross, J. A.; Levy, Y.; Kolb, J. S.; Turmaine, M.; Holt, M.; Ripolone, M.; Moggio, M.; Fiorillo, C.; Lindqvist, J.; Figeac, N.; Zammit, P.; Jungbluth, H.; Vissing, J.; Witting, N.; Granzier, H.; Zanoteli, E.; Hardeman, E. C.; Wallgren-Pettersson, C.; Ochala, J.

10.1101/518522 — cell biology — Posted on 2019-01-14

1899 Heparan sulfate expression on B cells modulates IgM expression in aged mice and steady-state plasma cells

Trujillo, D. L.; Jarousse, N.; Coscoy, L.

10.1101/514588 — immunology — Posted on 2019-01-14

1900 Longitudinal Intravital Imaging of Biosensor-labeled In Situ Islet Beta Cells

Reissaus, C. A.; Twigg, A. N.; Orr, K. S.; Conteh, A. M.; Martinez, M. M.; Kamocka, M. M.; Day, R. N.; Tersey, S. A.; Dunn, K. W.; Mirmira, R. G.; Linnemann, A. K.

10.1101/518753 — cell biology — Posted on 2019-01-14

1901 Kinesin-5 promotes microtubule nucleation and assembly by stabilizing a lattice-competent conformation of tubulin

Chen, G.-Y.; Asenjo, A. B.; Chen, Y.; Mascaro, J.; Arginteanu, D. F. J.; Sosa, H. J.; Hancock, W. O.

10.1101/520072 — biophysics — Posted on 2019-01-14

1902 Recognizing off-sample mass spectrometry images with machine and deep learning

Ovchinnikova, K.; Kovalev, V.; Stuart, L.; Alexandrov, T.

10.1101/518977 — bioinformatics — Posted on 2019-01-14

1903 A novel blaSIM-1-carrying megaplasmid pSIM-1-BJ01 isolated from clinical Klebsiella pneumonia

Lü, Y.; Liang, H.; Zhang, W.; Liu, J.; Wang, S.; Hu, H.

10.1101/519082 — epidemiology — Posted on 2019-01-14

1904 Molecular characterization of Chlamydomonas reinhardtii telomeres and telomerase mutants

Eberhard, S.; Valuchova, S.; Ravat, J.; Jolivet, P.; Bujaldon, S.; Lemaire, S. D.; Wollman, F.-A.; Teixeira, M. T.; Riha, K.; Xu, Z.

10.1101/519991 — plant biology — Posted on 2019-01-14

1905 How many bits of information can be transferred within a protein and how fast?

Hacisuleyman, A.; Erman, B.

10.1101/519827 — biophysics — Posted on 2019-01-14

1906 O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Zhang, B.; Li, M.-D.; Yin, R.; Liu, Y.; Yang, Y.; Mitchell-Richards, K. A.; Nam, J. H.; Li, R.; Wang, L.; Iwakiri, Y.; Chung, D.; Robert, M. E.; Ehrlich, B. E.; Bennett, A. M.; Yu, J.; Nathanson, M.; Yang, X.

10.1101/519975 — physiology — Posted on 2019-01-14

1907 The off-target kinase landscape of clinical PARP inhibitors

Antolin, A. A.; Ameratunga, M.; Banerji, U.; Clarke, P.; Workman, P.; Al-Lazikani, B.

10.1101/520023 — pharmacology and toxicology — Posted on 2019-01-14

1908 ScaR - A tool for sensitive detection of known fusion transcripts: Establishing prevalence of fusions in testicular germ cell tumors

Zhao, S.; Hoff, A. M.; Skotheim, R. I.

10.1101/518316 — bioinformatics — Posted on 2019-01-14

1909 A GWAS-Derived Polygenic Score for Interleukin-1β is Associated with Hippocampal Volume in Two Samples

Avinun, R.; Nevo, A.; Knodt, A. R.; Elliott, M. L.; Hariri, A. R.

10.1101/516989 — neuroscience — Posted on 2019-01-14

1910 Dynamics of chromosome replication and its relationship to predatory attack lifestyles in Bdellovibrio bacteriovorus

Makowski, L.; Trojanowski, D.; Till, R.; Lambert, C.; Lowry, R.; Sockett, R. E.; Zakrzewska-Czerwinska, J.

10.1101/519983 — microbiology — Posted on 2019-01-14

1911 Genetic variants of calcium and vitamin D metabolism in kidney stone disease

Howles, S. A.; Wiberg, A.; Goldsworthy, M.; Bayliss, A. L.; Grout, E.; Tanikawa, C.; Kamatani, Y.; Terao, C.; Takahashi, A.; Kubo, M.; Matsuda, K.; Thakker, R. V.; Turney, B. W.; Furniss, D.

10.1101/515882 — genomics — Posted on 2019-01-14

1912 Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses

Buckley, J.; Daly, R.; Cobbold, C.; Burgess, K.; Mable, B.

10.1101/520015 — evolutionary biology — Posted on 2019-01-14

1913 Novel mutations within PRSS1 Gene that could potentially cause hereditary pancreatitis: Using Comprehensive in silico Approach

Mustafa, M. I.; Abdelmoneim, A. H.; Elfadol, N. M.; Osman, S. A.; Abdelhameed, T. A.; Hassan, M. A.

10.1101/519926 — bioinformatics — Posted on 2019-01-14

1914 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

Wang, H.; Zhang, F.; Zeng, J.; Wu, Y.; Kemper, K. E.; Xue, A.; Zhang, M.; Powell, J. E.; Goddard, M. E.; Wray, N. R.; Visscher, P. M.; McRae, A. F.; Yang, J.

10.1101/519538 — genetics — Posted on 2019-01-14

1915 The regulatory function of dIno80 correlates with its DNA binding activity

Jain, S.; Maini, J.; Narang, A.; Maiti, S.; Brahmachari, V.

10.1101/519959 — developmental biology — Posted on 2019-01-14

1916 Training load and body composition in adults practicing cyclical exercises

Silva, R. S. B.; Souza, M. F.; Costa, M. d. S.; Franca, G. A. M.; Cardoso, G. A.; Batista, J. R. E.; Lopes, C. F. A.; Barbosa, F. K. L.; Silva, A. S.

10.1101/520189 — physiology — Posted on 2019-01-14

1917 A Zika vaccine based on chimpanzee adenovirus ChAdOx1 elicits lineage-transcending sterile immunity and prevents colonisation of brain and ovaries

Lopez-Camacho, C.; Dowall, S.; Graham, V.; Findlay-Wilson, S.; Rayner, E.; Chan Kim, Y.; Hewson, R.; Reyes-Sandoval, A.

10.1101/514877 — pathology — Posted on 2019-01-14

1918 RHO-1 and the Rho GEF RHGF-1 interact with UNC-6/Netrin signaling to regulate growth cone protrusion and microtubule organization in C. elegans

Gujar, M. R.; Stricker, A.; Lundquist, E. A.

10.1101/520262 — neuroscience — Posted on 2019-01-14

1919 Pilot study to evaluate the effect of a calcium and vitamin D-containing oral bolus on serum calcium levels in early lactation Holstein dairy cows

Shock, D. A.; Renaud, D. L.; Roche, S. M.; Genore, R. L.; Reynen, R.; Olson, M. E.

10.1101/520221 — epidemiology — Posted on 2019-01-14

1920 The generation of a comprehensive spectral library for the analysis of the guinea pig proteome by SWATH-MS.

Palmowski, P.; Watson, R.; Europe-Finner, N.; Karolczak-Bayatti, M.; Porter, A.; Treumann, A.; Taggart, M. J.

10.1101/514760 — biochemistry — Posted on 2019-01-14

1921 PKC regulates the production of fibroblast growth factor 23 (FGF23)

Bär, L.; Hase, P.; Föller, M.

10.1101/520254 — physiology — Posted on 2019-01-14

1922 Choice of birth place among antenatal clinic attendees in rural mission hospitals in Ebonyi State, South-East Nigeria

Ajah, L. O.; Onu, F. A.; Ogbuinya, O. C.; Ajah, M. I.; Ozumba, B. C.; Agbata, A. T.; Onoh, R. C.; Ekwedigwe, K. C.; Leonard O. Ajah, Fidelis A. Onu, Oliver C. Ogbuinya,Monique I. Ajah,Benjamin C. Ozumba,Anthony T.Agb,

10.1101/520213 — epidemiology — Posted on 2019-01-14

1923 Peptidoglycan Mediates Loa22 and Toll-like Receptor 2 Interactions in Pathogenic Leptospira

Hsu, S.-H.; Chang, M.-Y.; Ko, Y.-C.; Chou, L.-F.; Tian, Y.-C.; Hung, C.-C.; Yang, C.-W.

10.1101/520288 — biochemistry — Posted on 2019-01-14

1924 Comparative Population Genomics of Bread Wheat (Triticum aestivum) Reveals Its Cultivation and Breeding History in China

Chen, H.; Jiao, C.; Wang, Y.; Wang, Y.; Tian, C.; Yu, H.; Wang, J.; Wang, X.; Lu, F.; Fu, X.; Xue, Y.; Jiang, W.; Ling, H.; Lu, H.; Jiao, Y.

10.1101/519587 — plant biology — Posted on 2019-01-14

1925 Increase in stable isotope ratios driven by metabolic alterations in amphipods exposed to the beta-blocker propranolol

Ek, C.; Yu, Z.; Garbaras, A.; Oskarsson, H.; Wiklund, A.-K. E.; Kumblad, L.; Gorokhova, E.

10.1101/520205 — ecology — Posted on 2019-01-14

1926 One-time Nitrogen Fertilization Shifts Switchgrass Soil Microbiomes within a Context of Larger Spatial and Temporal Variation

Chen, H.; Yang, Z. K.; Yip, D.; Morris, R. H.; Lebreux, S. J.; Cregger, M. A.; Klingeman, D. M.; Hui, D.; Hettich, R. L.; Wilhelm, S. W.; Wang, G.; Löffler, F. E.; Schadt, C. W.

10.1101/520239 — ecology — Posted on 2019-01-14

1927 N-terminal mutants of human apolipoprotein A-I: structural perturbations associated to protein misfolding

Gaddi, G. M.; Gisonno, R. A.; Rosu, S. A.; Curto, L. M.; Elias, E. E.; Prieto, E. D.; Schinella, G. R.; Finarelli, G. S.; Cortez, M. F.; Ramella, N. A.; Tricerri, M. A.

10.1101/520171 — biophysics — Posted on 2019-01-14

1928 Optical determination of absolute membrane potential

Lazzari-Dean, J. R.; Gest, A. M. M.; Miller, E.

10.1101/519736 — physiology — Posted on 2019-01-14

1929 Improved state change estimation in dynamic functionalconnectivity using hidden semi-Markov models

Shappell, H. M.; Caffo, B. S.; Pekar, J. J.; Lindquist, M.

10.1101/519868 — neuroscience — Posted on 2019-01-14

1930 Impaired Regulation of Redox Transcriptome during the Differentiation of iPSCs into Induced Cardiomyocytes (iCMs)

Shanmugam, G.; Crossman, D.; Rajasingh, J.; Dalley, B.; Zhang, J.; Namakkal-Soorappan, R.

10.1101/519793 — cell biology — Posted on 2019-01-14

1931 A single microRNA system controls complex movement in morphologically distinct forms of Drosophila

Issa, R.; Picao-Osorio, J.; Rito, N.; Chiappe, M. E.; Alonso, C. R.

10.1101/511881 — neuroscience — Posted on 2019-01-14

1932 Life-history traits inform on population trends when assessing the conservation status of a declining tiger shark population

Brown, C.; Roff, G.

10.1101/395509 — ecology — Posted on 2019-01-13

1933 Antitumor effects of Tv1 venom peptide in liver cancer

Holford, M.; Ogunwobi, O.; Huaman, J.; Filipenko, P.; Lyudmer, M.; Hossain, M.; Santamaria, C.; Huang, K.; Anand, P.

10.1101/518340 — cancer biology — Posted on 2019-01-14

1934 Knockdown of DGKZ induces apoptosis and G2/M phase arrest in human acute myeloid leukemia HL-60 cells

Chao, X.; Dong, C.; Li, H.; Tian, Y.; Li, X.; Wang, B.; Zhai, D.; Bai, Y.

10.1101/474221 — cancer biology — Posted on 2019-01-13

1935 Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

Holland, D.; Frei, O.; Desikan, R.; Fan, C.-C.; Shadrin, A. A.; Smeland, O. B.; Sundar, V. S.; Thompson, P.; Andreassen, O. A.; Dale, A. M.

10.1101/133132 — genomics — Posted on 2019-01-13

1936 Dowsing for salinity tolerance related genes in chickpea through genome wide association and in silico PCR analysis

Ahmed, S. M.; Alsamman, A. M.; Mubarak, M. H.; Badawy, M. A.; Kord, M. A.; Momtaz, O. A.; Hamwieh, A.

10.1101/519744 — genomics — Posted on 2019-01-13

1937 Transcriptomic evidence for dense peptidergic neuromodulation networks in mouse cortex

Smith, S. J.; Sumbul, U.; Graybuck, L. T.; Collman, F.; Seshamani, S.; Gala, R.; Gliko, O.; Elabbady, L.; Miller, J.; Bakken, T.; Yao, Z.; Lein, E.; Zeng, H.; Tasic, B.; Hawrylycz, M.

10.1101/519694 — neuroscience — Posted on 2019-01-13

1938 GWAS identifies nine nephrolithiasis susceptibility loci related with metabolic and crystallization pathways

Tanikawa, C.; Kamatani, Y.; Terao, C.; Usami, M.; Takahashi, A.; Momozawa, Y.; Suzuki, K.; Ogishima, S.; Shimizu, A.; Satoh, M.; Matsuo, K.; Mikami, H.; Naito, M.; Wakai, K.; Yamaji, T.; Sawada, N.; Iwasaki, M.; Tsugane, S.; Kohri, K.; Yasui, T.; Murakami, Y.; Kubo, M.; Matsuda, K.

10.1101/519553 — genetics — Posted on 2019-01-13

1939 Fast and accurate reference-guided scaffolding of draft genomes

Alonge, M.; Soyk, S.; Ramakrishnan, S.; Wang, X.; Goodwin, S.; Sedlazeck, F. J.; Lippman, Z. B.; Schatz, M. C.

10.1101/519637 — bioinformatics — Posted on 2019-01-13

1940 cellHarmony: Cell-level matching and comparison of single-cell transcriptomes

DePasquale, E. A.; Ferchen, K.; Hay, S.; Grimes, H. L.; Salomonis, N.

10.1101/412080 — bioinformatics — Posted on 2019-01-13

1941 Structural basis of HMCES interactions with DNA reveals multivalent substrate recognition

Halabelian, L.; Ravichandran, M.; Li, Y.; Zheng, H.; Aravind, L.; Rao, A.; Arrowsmith, C. H.

10.1101/519595 — biochemistry — Posted on 2019-01-13

1942 Foliar fungi alter reproductive timing and allocation in Arabidopsis under normal and water-stressed conditions

Zahn, G.; Amend, A. S.

10.1101/519678 — plant biology — Posted on 2019-01-13

1943 A brainstem-central amygdala circuit underlies defensive responses to learned threats

Gu, Y.; Vazey, E. M.; Aston-Jones, G.; Lin, L.; LeDoux, J. E.; Sears, R. M.

10.1101/519249 — neuroscience — Posted on 2019-01-13

1944 Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification

Argelaguet, R.; Mohammed, H.; Clark, S.; Stapel, C.; Krueger, C.; Kapourani, C. A.; Xiang, Y.; Hanna, C.; Smallwood, S.; Ibarra Soria, X.; Buettner, F.; Sanguinetti, G.; Krueger, F.; Xie, W.; Rugg-Gunn, P.; Kelsey, G.; Dean, W.; Nichols, J.; Stegle, O.; Marioni, J. C.; Reik, W.

10.1101/519207 — developmental biology — Posted on 2019-01-13

1945 Pan-cancer genomic amplifications underlie a Wnt hyperactivation phenotype associated with stem cell-like features leading to poor prognosis

Chang, W. H.; Lai, A. G.

10.1101/519611 — cancer biology — Posted on 2019-01-13

1946 A comprehensive evaluation of long read error correction methods

Zhang, H.; Jain, C.; Aluru, S.

10.1101/519330 — bioinformatics — Posted on 2019-01-13

1947 Neural Mediators of Altered Perceptual Choice and Confidence Using Social Information

Saha Roy, T.; Giri, B.; Saha Chowdhury, A.; Mazumder, S.; Das, K.

10.1101/516963 — neuroscience — Posted on 2019-01-13

1948 Olfactory Co-Stimulation Influences Intranasal Somatosensory Perception

Karunanayaka, P. R.; Lu, J.; Yang, Q. X.; Sathian, K.

10.1101/519439 — neuroscience — Posted on 2019-01-13

1949 Molecular framework for TIR1/AFB-Aux/IAA-dependent auxin sensing controlling adventitious rooting in Arabidopsis

Lakehal, A.; Chaabouni, S.; Cavel, E.; Le Hir, R.; Ranjan, A.; Raneshan, Z.; Novak, O.; Pacurar, D. I.; Perrone, I.; Jobert, F.; Gutierrez, L.; Bako, L.; Bellini, C.

10.1101/518357 — plant biology — Posted on 2019-01-13

1950 Skeletal descriptions of shape provide unique and privileged perceptual information for object recognition

Ayzenberg, V.; Lourenco, S. F.

10.1101/518795 — neuroscience — Posted on 2019-01-13

1951 Molecular Genetic Analysis of RB1 gene among Sudanese children with Retinoblastoma

Ibrahim, N. O.; Saleem, M.; Eltayeb, E.; Mekki, S.; Elnaim, E.; Idris, A. B.; Bashir, S.; Salim, M. A.; Hassan, M. A.

10.1101/519306 — molecular biology — Posted on 2019-01-13

1952 Experimental and mathematical insights on the competition between poliovirus and a defective interfering genome

Shirogane, Y.; Rousseau, E.; Voznica, J.; Rouzine, I.; Bianco, S.; Andino, R.

10.1101/519751 — microbiology — Posted on 2019-01-13

1953 Chromatin modifiers alter recombination between divergent DNA sequences

Chakraborty, U.; Mackenroth, B.; Alani, E. E.

10.1101/519397 — genetics — Posted on 2019-01-13

1954 Genetic control of pod dehiscence in domesticatedcommon bean: Associations with range expansionand local aridity conditions

Parker, T.; Berny Mier y Teran, J. C.; Palkovic, A.; Jernstedt, J.; Gepts, P.

10.1101/517516 — plant biology — Posted on 2019-01-13

1955 Behavioural Evaluation of the Anticonvulsant Properties of the Traditional Medicine Anonna Senegalensis on Parabss Drosophila melanogaster Mutants.

Dare, S.; Merlo, E.; Ekanem, P. E.; Berni, J.

10.1101/519322 — pharmacology and toxicology — Posted on 2019-01-13

1956 Orientation-selective adaptation improves perceptual grouping

Pinchuk-Yacobi, N.; Sagi, D.

10.1101/519561 — neuroscience — Posted on 2019-01-13

1957 Genome-wide patterns of population structure and linkage disequilibrium in farmed Nile tilapia (Oreochromis niloticus)

Yoshida, G.; Barria, A.; Caceres, G.; Correa, K.; Jedlicki, A.; Cadiz, M. I.; Lhorente Caussade, J. P.; Yanez, J. M.

10.1101/519801 — genomics — Posted on 2019-01-13

1958 TooManyCells identifies and visualizes relationships of single-cell clades

Schwartz, G. W.; Petrovic, J.; Fasolino, M.; Zhou, Y.; Cai, S.; Xu, L.; Pear, W. S.; Vahedi, G.; Faryabi, R. B.

10.1101/519660 — bioinformatics — Posted on 2019-01-13

1959 Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

Poos, A.; Kordass, T.; Kolte, A.; Ast, V.; Oswald, M.; Rippe, K.; Koenig, R.

10.1101/513259 — bioinformatics — Posted on 2019-01-13

1960 Memory-driven computing accelerates genomic data processing

Becker, M.; Chabbi, M.; Warnat-Herresthal, S.; Klee, K.; Schulte-Schrepping, J.; Biernat, P.; Guenther, P.; Bassler, K.; Craig, R.; Schultze, H.; Singhal, S.; Ulas, T.; Schultze, J. L.

10.1101/519579 — bioinformatics — Posted on 2019-01-13

1961 In vitro and in silico identification of the mechanism of interaction of antimalarial drug - artemisinin with human serum albumin and genomic DNA

Ginosyan, S.; Grabski, H.; Tiratsuyan, S.

10.1101/519710 — biochemistry — Posted on 2019-01-13

1962 A Data-Driven Transcriptional Taxonomy of Adipogenic Chemicals to Identify Emerging Metabolic Health Threats

Kim, S.; Reed, E.; Monti, S.; Schlezinger, J.

10.1101/519629 — pharmacology and toxicology — Posted on 2019-01-13

1963 Developmental Deficits in Thalamic Binocular Integration Revealed by In Vivo Thalamocortical Axon Imaging

Huh, C. Y. L.; Abdelaal, K.; Salinas, K. J.; Gu, D.; Zeitoun, J.; Figueroa Velez, D. X.; Peach, J. P.; Fowlkes, C. C.; Gandhi, S. P.

10.1101/484774 — neuroscience — Posted on 2019-01-13

1964 Genetic dysregulation of gene expression and splicing during a ten-year period of human aging

Balliu, B.; Durrant, M.; de Goede, O.; Abell, N.; Li, X.; Liu, B.; Gloudemans, M. J.; Cook, N. L.; Smith, K. S.; Pala, M.; Cucca, F.; Schlessinger, D.; Jaiswal, S.; Sabatti, C.; Lind, L.; Ingelsson, E.; Montgomery, S. B.

10.1101/519520 — genomics — Posted on 2019-01-13

1965 Transcriptional landscape of DNA repair genes underpins a pan-cancer prognostic signature associated with cell cycle dysregulation and tumor hypoxia

Chang, W. H.; Lai, A. G.

10.1101/519603 — cancer biology — Posted on 2019-01-13

1966 Attentional modulation of neural phase is enhanced by short-term training and linked to musical experience

Laffere, A.; Dick, F.; Tierney, A.

10.1101/519181 — neuroscience — Posted on 2019-01-13

1967 Evaluation of the novel culture-based FAST-T system allowing selection of optimal antibiotics for critically ill patients within 4 h (for other than bloodstream infectious).

Tetz, G.; Tetz, V.

10.1101/519348 — microbiology — Posted on 2019-01-13

1968 Capturing the Diversity of Subsurface Microbiota - Choice of Carbon Source for Microcosm Enrichment and Isolation of Groundwater Bacteria

Wu, X.; Spencer, S.; Voriskova, J.; Alm, E. J.; Chakraborty, R.

10.1101/517854 — microbiology — Posted on 2019-01-13

1969 HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury

Valente, M.; Resende, T. P.; Nascimento, D. S.; Burlen-Defranoux, O.; Dupont, B.; Cumano, A.; Pinto-do-O, P.

10.1101/518530 — developmental biology — Posted on 2019-01-13

1970 Estimation of permutation-based metabolome-wide significance thresholds

Peluso, A.; Glen, R.; Ebbels, T. M. D.

10.1101/478370 — bioinformatics — Posted on 2019-01-13

1971 Semantic Integration of Clinical Laboratory Tests from Electronic Health Records for Deep Phenotyping and Biomarker Discovery

Zhang, X. A.; Yates, A.; Vasilevsky, N.; Gourdine, J.; Carmody, L. C.; Danis, D.; Joachimiak, M. P.; Ravanmehr, V.; Pfaff, E. R.; Champion, J.; Robasky, K.; Xu, H.; Fecho, K.; Walton, N. A.; Zhu, R.; Ramsdill, J.; Mungall, C.; Kohler, S.; Haendel, M. A.; McDonald, C.; Vreeman, D. J.; Peden, D. B.; Chute, C. G.; Robinson, P. N.

10.1101/519231 — bioinformatics — Posted on 2019-01-13

1972 Systems Biology Theory Clarification of a Controversy in Pancreatic Beta Cell Regeneration

Cai, H.; Cheng, R.; Yuan, R.; Zhu, X.; Ao, P.

10.1101/469320 — systems biology — Posted on 2019-01-13

1973 Identification of biological mechanisms underlying a multidimensional ASD phenotype using machine learning

Asif, M.; Martiniano, H. F. M. C.; Marques, A. R.; Santos, J. X.; Vilela, J.; Rasga, C.; Oliveira, G.; Couto, F. M.; Vicente, A. M.

10.1101/470757 — systems biology — Posted on 2019-01-13

1974 Hippocampal-entorhinal transformations in abstract frames of reference

Kaplan, R.; Friston, K. J.

10.1101/414524 — neuroscience — Posted on 2019-01-13

1975 The integration of visual and target signals in V4 and IT during visual object search

Roth, N. C.; Rust, N.

10.1101/370049 — neuroscience — Posted on 2019-01-13

1976 Green-gradient based canopy segmentation: A multipurpose image mining technique with potential use in crop phenotyping and canopy studies

Haghshenas, A.; Emam, Y.

10.1101/241786 — plant biology — Posted on 2019-01-13

1977 Rice annexin OsANN4 interacting with OsCDPK24, reduces root aerenchyma formation by modulating H2O2 under ABA treatment

Zhu, Z.; Zhang, Q.; Song, T.; Guan, C.; Gao, Y.; Ma, J.; Qi, Z.; Liu, J.; Zhu, Y.

10.1101/519199 — plant biology — Posted on 2019-01-13

1978 Attentional modulation of neural phase is enhanced by short-term training and linked to musical experience

Laffere, A.; Dick, F.; Tierney, A.

10.1101/519181 — neuroscience — Posted on 2019-01-13

1979 Highly-accurate long-read sequencing improves variant detection and assembly of a human genome

Wenger, A. M.; Peluso, P.; Rowell, W. J.; Chang, P.-C.; Hall, R. J.; Concepcion, G. T.; Ebler, J.; Fungtammasan, A.; Kolesnikov, A.; Olson, N. D.; Toepfer, A.; Chin, C.-S.; Alonge, M.; Mahmoud, M.; Qian, Y.; Phillippy, A. M.; Schatz, M. C.; Myers, G.; DePristo, M. A.; Ruan, J.; Marschall, T.; Sedlazeck, F. J.; Zook, J. M.; Li, H.; Koren, S.; Carroll, A.; Rank, D. R.; Hunkapiller, M. W.

10.1101/519025 — genomics — Posted on 2019-01-13

1980 Characterizing and inferring epistasis via direct evolutionary couplings in models of allostery

Bravi, B.; Ravasio, R.; Brito, C.; Wyart, M.

10.1101/519116 — biophysics — Posted on 2019-01-13

1981 GRep: Gene Set Representation via Gaussian Embedding

wang, S.; Flynn, E.; Altman, R.

10.1101/519033 — bioinformatics — Posted on 2019-01-13

1982 Repertoire-Based Diagnostics Using Statistical Biophysics

Arora, R.; Kapllinsky, J.; Li, A.; Arnaout, R.

10.1101/519108 — immunology — Posted on 2019-01-13

1983 Many unreported crop pests and pathogens are probably already present

Bebber, D. P.; Field, E. M.; Gui, H.; Mortimer, P.; Holmes, T.; Gurr, S. J.

10.1101/519223 — ecology — Posted on 2019-01-13

1984 Early urinary protein changes in the tumor-forming process of the NuTu-19 lung metastasis

Wei, J.; Ni, N.; Meng, W.; Huan, Y.; Gao, Y.

10.1101/519215 — cancer biology — Posted on 2019-01-13

1985 Modeling the dynamics of Let-7-coupled gene regulatory networks linking cell proliferation to malignant transformation

Gerard, C.; Lemaigre, F.; Gonze, D.

10.1101/519165 — systems biology — Posted on 2019-01-13

1986 Benchmarking Database Systems for Genomic Selection Implementation

Nti-Addae, Y.; Matthews, D.; Ulat, V. J.; Syed, R.; Sempere, G.; Petel, A.; Renner, J.; Larmande, P.; Guignon, V.; Jones, E.; Robbins, K.

10.1101/519017 — genomics — Posted on 2019-01-13

1987 Fire ! The spread of the Caribbean fire coral Millepora alcicornis in the Eastern Atlantic.

Wirtz, P.; Zilberberg, C.

10.1101/519041 — ecology — Posted on 2019-01-13

1988 Novel signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size

Eid Mutlak, Y.; Aweida, D.; Volodin, A.; Ayalon, B.; Dahan, N.; Parnis, A.; Cohen, S.

10.1101/517789 — cell biology — Posted on 2019-01-13

1989 Genetic Risk for Rheumatoid Arthritis is Associated with Increased Striatal Volume in Healthy Young Adults

Avinun, R.; Nevo, A.; Hariri, A. R.

10.1101/519132 — neuroscience — Posted on 2019-01-13

1990 Motion direction representation in multivariate electroencephalography activity for smooth pursuit eye movements

Lee, J.; Jeong, W.; Kim, S.; Kim, Y.-J.

10.1101/519074 — neuroscience — Posted on 2019-01-13

1991 Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation require Lysine Specific Demethylase (LSD)1-dependent recruitment of the BHC complex

McClellan, D.; Casey, M. J.; Bareyan, D.; Lucente, H.; Ours, C.; Velinder, M.; Singer, J.; Lone, M. D.; Sun, W.; Coria, Y.; Mason, C. C.; Engel, M. E.

10.1101/519090 — molecular biology — Posted on 2019-01-13

1992 PHYSIOLOGICAL GROWTH INDICES OF MAIZE (Zea mays L.) GENOTYPES IN SYLHET

Islam, M. T.; Islam, A. F. M. S.; Uddin, M. S.

10.1101/518993 — plant biology — Posted on 2019-01-13

1993 Topographic organization of the third tier dorsomedial visual cortex in the macaque

Hadjidimitrakis, K.; Bakola, S.; Chaplin, T.; Yu, H.-H.; Alanazi, O.; Chan, J. M. H.; Worthy, K.; Rosa, M.

10.1101/519009 — neuroscience — Posted on 2019-01-13

1994 The genome of cowpea (Vigna unguiculata Walp.)

Lonardi, S.; Munoz-Amatriain, M.; Liang, Q.; Shu, S.; Wanamaker, S. I.; Lo, S.; Tanskanen, J.; Schulman, A. H.; Zhu, T.; Luo, M.-C.; Alhakami, H.; Ounit, R.; Hasan, A. M.; Verdier, J.; Roberts, P. A.; Santos, J. R.; Ndeve, A.; Dolezel, J.; Vrana, J.; Hokin, S. A.; Farmer, A. D.; Cannon, S. B.; Close, T. J.

10.1101/518969 — genomics — Posted on 2019-01-13

1995 Acoustic community structure and seasonal turnover in tropical South Asian birds

Krishnan, A.

10.1101/518985 — ecology — Posted on 2019-01-13

1996 Tackling the research capacity challenge in Africa: An overview of African-led approaches to strengthen research capacity

Ngongalah, L. N.; Rawlings, N. N.; Wepngong, E. N.; Musisi, J. M.; Ngwayu, C. N.; Mumah, S.

10.1101/518498 — scientific communication and education — Posted on 2019-01-13

1997 Do Synthesis Centers Synthesize? A Semantic Analysis of Diversity and Performance

Hackett, E. J.; Leahey, E.; Parker, J. N.; Rafols, I.; Hampton, S.; Corte, U.; Drake, J. M.; Penders, B.; Sheble, L.; Vermeulen, N.; Vision, T.

10.1101/518605 — scientific communication and education — Posted on 2019-01-13

1998 Genomic evidence of genetic variation with pleiotropic effects on caterpillar fitness and plant traits in a model legume

Gompert, Z.; Brady, M.; Chalyavi, F.; Saley, T. C.; Philbin, C.; Tucker, M. J.; Forister, M.; Lucas, L.

10.1101/518951 — evolutionary biology — Posted on 2019-01-13

1999 Tracking the popularity and outcomes of all bioRxiv preprints

Abdill, R. J.; Blekhman, R.

10.1101/515643 — scientific communication and education — Posted on 2019-01-13

2000 Expression of glucocorticoid and mineralocorticoid receptor genes co-vary with a stress-related colour signal in barn owls

Beziers, P.; Ducrest, A.-L.; San-Jose, L. M.; Simon, C.; Roulin, A.

10.1101/517060 — physiology — Posted on 2019-01-13

2001 A heuristic feature cluster search algorithm for precise functional brain mapping

Asadi, N.; Wang, Y.; Olson, I.; Obradovic, Z.

10.1101/518480 — neuroscience — Posted on 2019-01-12

2002 Does testosterone impair men’s cognitive empathy? Evidence from two large-scale randomized controlled trials

Nadler, A.; Zava, D.; Ortiz, T.; Watson, N.; Carre, J.; Camerer, C.; Nave, G.

10.1101/516344 — neuroscience — Posted on 2019-01-13

2003 Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

Burmistrova, O.; Olias-Arjona, A.; Eremeeva, T.; Shishov, D.; Zakurdaeva, K.; Almeida, A.; Fedichev, P. O.; Bolanos, J. P.

10.1101/518092 — neuroscience — Posted on 2019-01-12

2004 Defining the core essential genome of Pseudomonas aeruginosa

Poulsen, B. E.; Yang, R.; Clatworthy, A. E.; White, T.; Osmulski, S. J.; Li, L.; Penaranda, C.; Lander, E. S.; Shoresh, N.; Hung, D. T.

10.1101/396689 — microbiology — Posted on 2019-01-12

2005 A statistical modeling framework to assess cross-frequency coupling while accounting for confounding effects

Nadalin, J. K.; Martinet, L.-E.; Widge, A. S.; Cash, S. S.; Eden, U.; Kramer, M. A.

10.1101/519470 — neuroscience — Posted on 2019-01-12

2006 CIC-DUX4 expression drives the development of small round cell sarcoma in transgenic zebrafish: a new model revealing a role for ETV4 in CIC-mediated sarcomagenesis

Watson, S.; Kendall, G. C.; Rakheja, D.; McFaul, M. E.; Draper, B. W.; Tirode, F.; Delattre, O.; Amatruda, J. F.

10.1101/517722 — cancer biology — Posted on 2019-01-12

2007 Stereotyped large amplitude cortical LFP events can be clustered and reveal precisely ordered phase-locking in neuronal populations

Mitelut, C.; Spacek, M.; Chan, A. W.; Murphy, T. H.; Swindale, N. V.

10.1101/519454 — neuroscience — Posted on 2019-01-12

2008 Targeting tumor intrinsic metabolic node in pancreatic cancer causes tumor regression, remodels extracellular matrix and sensitizes to anti-PD1 therapy.

Sharma, N. S.; Gupta, V. K.; Garrido, V. T.; Hadad, R.; Durden, B. C.; Kesh, K.; Giri, B.; Ferrantella, A.; Dudeja, V.; Saluja, A.; Banerjee, S.

10.1101/519462 — cancer biology — Posted on 2019-01-12

2009 Mitigating Data Scarcity in Protein Binding Prediction Using Meta-Learning

Luo, Y.; Ma, J.; Zhao, X.; Su, Y.; Liu, Y.; Ideker, T.; Peng, J.

10.1101/519413 — bioinformatics — Posted on 2019-01-12

Hage, R.; Dierick, F.; Roussel, N.; Pitance, L.; Detrembleur, C.

10.1101/519488 — physiology — Posted on 2019-01-12

2011 Phase resetting in human auditory cortex to visual speech

Megevand, P.; Mercier, M. R.; Groppe, D. M.; Zion Golumbic, E.; Mesgarani, N.; Beauchamp, M. S.; Schroeder, C. E.; Mehta, A. D.

10.1101/405597 — neuroscience — Posted on 2019-01-12

2012 3D-printing Enabled Micro-assembly of Microfluidic Electroporation System for 3D Tissue Engineering

Zhu, Q.; Hamilton, M.; He, M.

10.1101/519496 — bioengineering — Posted on 2019-01-12

2013 Neural circuitry of dialects through social learning in Drosophila.

Kacsoh, B. Z.; Bozler, J.; Hodge, S.; Bosco, G.

10.1101/511857 — neuroscience — Posted on 2019-01-12

2014 Targeting of RBM10 to S1-1 Nuclear Bodies: Targeting Sequences and its Biological Significance

Wang, L.-Y.; Xiao, S.-J.; Kunimoto, H.; Tokunaga, K.; Kojima, H.; Kimura, M.; Yamamoto, T.; Yamamoto, N.; Hong, Z.; Nishio, K.; Yamane, H.; Tani, T.; Nakajima, K.; Iguchi, H.; Inoue, A.

10.1101/516831 — molecular biology — Posted on 2019-01-12

2015 The bat influenza H17N10 can be neutralized by broadly-neutralizing monoclonal antibodies and its neuraminidase can facilitate viral egress.

Carnell, G.; Giotis, E.; Grehan, K.; Ferrara, F.; Mather, S.; Molesti, E.; Scott, S.; Pessi, A.; Lacek, K.; Temperton, N.

10.1101/499947 — microbiology — Posted on 2019-01-12

2016 The landscape of DNA methylation associated with the transcriptomic network in laying hens and broilers generates insight into embryonic muscle development in chicken

Liu, Z.; Shen, X.; Han, S.; Wang, Y.; Zhu, Q.; Cui, C.; He, H.; Zhao, J.; Chen, Y.; Zhang, Y.; Ye, L.; Zhang, Z.; Liu, D.; Zhao, X.; Yin, H.

10.1101/470278 — bioinformatics — Posted on 2019-01-12

2017 Voluntary control of illusory contour formation

Harrison, W. J.; Rideaux, R.

10.1101/219279 — neuroscience — Posted on 2019-01-12

2018 Understanding the survival of Zika virus in a vector interconnected sexual contact network

Ferdousi, T.; Cohnstaedt, L. W.; McVey, D. S.; Scoglio, C. M.

10.1101/518613 — epidemiology — Posted on 2019-01-12

2019 Prevalence and risk factors of postpartum depression among women living in urban slums of Dhaka, Bangladesh

Azad, R.; Fahmi, R.; Shrestha, S.; Joshi, H.; Hasan, M.; Khan, A. N. S.; Chowdhury, M. A. K.; Arifeen, S. E.; Billah, S. M.

10.1101/514729 — epidemiology — Posted on 2019-01-12

2020 Plasmodium caprae infection is negatively correlated with infection of Theileria ovis and Anaplasma ovis in goats

Hakimi, H.; Sarani, A.; Takeda, M.; Kaneko, O.; Asada, M.

10.1101/515684 — epidemiology — Posted on 2019-01-12

2021 Determinants of Cancer-specific Quality of Life in Veteran Lung Cancer Survivors Eligible for Long-Term Cure

Ha, D.; Ries, A. L.; Swigris, J. J.

10.1101/518910 — epidemiology — Posted on 2019-01-12

2022 Effects of water, sanitation, handwashing and nutritional interventions on soil-transmitted helminth infections in young children: a cluster-randomized controlled trial in rural Bangladesh

Ercumen, A.; Benjamin-Chung, J.; Arnold, B. F.; Lin, A.; Hubbard, A. E.; Stewart, C.; Rahman, Z.; Parvez, S. M.; Unicomb, L.; Rahman, M.; Haque, R.; Colford, J. M.; Luby, S. P.

10.1101/512509 — clinical trials — Posted on 2019-01-12

2023 Grey Matter Age Prediction as a Biomarker for Risk of Dementia: A Population-based Study

Wang, J.; Knol, M.; Tiulpin, A.; Dubost, F.; de Bruijne, M.; Vernooij, M.; Adams, H.; Ikram, M. A.; Niessen, W.; Roshchupkin, G.

10.1101/518506 — epidemiology — Posted on 2019-01-12

2024 The projected economic and health burden of uncontrolled asthma in the United States

Mohsen, Y.; Adibi, A.; Safari, A.; FitzGerald, J. M.; Sadatsafavi, M.

10.1101/516740 — epidemiology — Posted on 2019-01-12

2025 Modeling cholera transmission and vaccination in a refugee camp

Havumaki, J.; Meza, R.; Phares, C. R.; Date, K.; Eisenberg, M. C.

10.1101/514406 — epidemiology — Posted on 2019-01-12

2026 Integrating Quality of Life and Survival Outcomes Cardiovascular Clinical Trials: Results from the PARTNER Trial

Spertus, J.; Hatfield, L. A.; Cohen, D. J.; Arnold, S. V.; Ho, M.; Jones, P. G.; Leon, M.; Zuckerman, B.; Spertus, J. A.

10.1101/513895 — clinical trials — Posted on 2019-01-12

2027 The Isolation and Identification of Fungi Gathered from Districts in Bangkok, Thailand Where Dengue Fever Is at Epidemic Levels

Kanchanaphum, P.; Wasinpiyamongkol, L.

10.1101/518241 — microbiology — Posted on 2019-01-12

2028 Comparison of antihypertensive drug classes for dementia prevention

Walker, V.; Davies, N.; Martin, R.; Kehoe, P.

10.1101/517482 — epidemiology — Posted on 2019-01-12

2029 Prevention of heart failure in hypertension: disentangling the role of evolving left ventricular hypertrophy and blood pressure lowering: the ALLHAT study

Johnson, K.; Oparil, S.; Davis, B. R.; Tereshchenko, L. G.

10.1101/514323 — clinical trials — Posted on 2019-01-12

2030 Potential influence of school-based lifestyle strategies among Australian Aboriginal and non-Aboriginal children: a cross-sectional comparison of adiposity and weight related behaviors between 2010 and 2015.

Hardy, L. L.; MacNiven, R.; Esgin, T.; Mihrshahi, S.

10.1101/518233 — epidemiology — Posted on 2019-01-12

2031 Network-based hierarchical population structure analysis for large genomic datasets

Greenbaum, G.; Rubin, A.; Templeton, A. R.; Rosenberg, N. A.

10.1101/518696 — genetics — Posted on 2019-01-11

2032 BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes

Ji, C.; Tang, M.; Zeidler, C.; Hoehfeld, J.; Johnson, G. V.

10.1101/518597 — neuroscience — Posted on 2019-01-11

2033 Happy you, happy me: expressive changes on a stranger’s voice recruit faster implicit processes than self-produced expressions

Rachman, L.; Aucouturier, J.-J.; Dubal, S.

10.1101/518324 — neuroscience — Posted on 2019-01-11

2034 Augmented Intelligence with Natural Language Processing Applied to Electronic Health Records is Useful for Identifying Patients with Non-Alcoholic Fatty Liver Disease at Risk for Disease Progression

Van Vleck, T. T.; Chan, L.; Coca, S. G.; Craven, C. K.; Do, R.; Ellis, S. B.; Kannry, J. L.; Loos, R. J.; Bonis, P. A.; Cho, J.; Nadkarni, G. N.

10.1101/518217 — bioinformatics — Posted on 2019-01-11

2035 Signal integration and information transfer in an allosterically regulated network

Shockley, E.; Rouzer, C. A.; Marnett, L. J.; Deeds, E. J.; Lopez, C. F.

10.1101/518514 — systems biology — Posted on 2019-01-11

2036 The genome of C57BL/6J \"Eve\", the mother of the laboratory mouse genome reference strain

Sarsani, V. K.; Raghupathy, N.; Fiddes, I. T.; Armstrong, J.; Thibaud-Nissen, F.; Zinder, O.; Bolisetty, M.; Howe, K.; Hinerfeld, D.; Ruan, X.; Rowe, L.; Barter, M.; Ananda, G.; Paten, B.; Weinstock, G. M.; Churchill, G. A.; Wiles, M. V.; Schneider, V. A.; Srivastava, A.; Reinholdt, L.

10.1101/517466 — genomics — Posted on 2019-01-11

2037 Controlling Organization and Forces in Active Matter Through Optically-Defined Boundaries

Ross, T. D.; Lee, H. J.; Qu, Z.; Banks, R. A.; Phillips, R.; Thomson, M.

10.1101/504456 — biophysics — Posted on 2019-01-11

2038 Artificial Dendritic Neurons Enable Self-Supervised Temporal Feature Extraction

Asabuki, T.; Fukai, T.

10.1101/517888 — neuroscience — Posted on 2019-01-11

2039 Prefrontal-posterior coupling mediates emotion transitions and their influence on executive function

Hao, Y.; Yao, L.; Smith, D. M.; Sorel, E.; Anderson, A. K.; Schumacher, E. H.; Evans, G. W.

10.1101/518860 — neuroscience — Posted on 2019-01-11

2040 Eurotium cristatum, a new fungi probiotic from Fuzhuan brick tea, alleviated obesity in mice by modulating gut microbiota

Kang, D.; Su, M.; Duan, Y.; Huang, Y.

10.1101/518068 — microbiology — Posted on 2019-01-11

2041 HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

Asquith, M.; Sternes, P. R.; Costello, M.-E.; Karstens, L.; Diamond, S.; Martin, T. M.; Spector, T. D.; le Cao, K.-A.; Rosenbaum, J. T.; Brown, M. A.

10.1101/517813 — microbiology — Posted on 2019-01-11

2042 A novel self-organizing embryonic stem cell system reveals signaling logic underlying the patterning of human ectoderm

Britton, G.; Heemskerk, I.; Hodge, R.; Qutub, A. A.; Warmflash, A.

10.1101/518803 — developmental biology — Posted on 2019-01-11

2043 Perivascular space fluid contributes to diffusion tensor imaging changes in white matter

Sepehrband, F.; Cabeen, R. P.; Choupan, J.; Barisano, G.; Law, M.; Toga, A. W.; the Alzheimers Disease Neuroimaging Initiative,

10.1101/395012 — neuroscience — Posted on 2019-01-11

2044 Post-hoc modification of linear models: combining machine learning with domain information to make solid inferences from noisy data

van Vliet, M.; Salmelin, R.

10.1101/518662 — neuroscience — Posted on 2019-01-11

2045 Phylogenomics reveals major diversification rate shifts in the evolution of silk moths and relatives

Hamilton, C. A.; St Laurent, R. A.; Dexter, K.; Kitching, I. J.; Breinholt, J. W.; Zwick, A.; Timmermans, M.; Barber, J. R.; Kawahara, A. Y.

10.1101/517995 — evolutionary biology — Posted on 2019-01-11

2046 ExtendAlign: a computational algorithm for delivering multiple, local end-to-end alignments for short sequences

Flores-Torres, M.; Gomez-Romero, L.; Hasse-Hernandez, J. I.; Aguilar-Ordonez, I.; Tovar, H.; Avendano-Vazquez, S. E.; Flores-Jasso, C. F.

10.1101/475707 — bioinformatics — Posted on 2019-01-11

2047 Insulin enhances presynaptic glutamate release in the nucleus accumbens via opioid receptor-mediated disinhibition

Oginsky, M. F.; Santana-Rodriguez, Z.; Ferrario, C.

10.1101/517797 — neuroscience — Posted on 2019-01-11

2048 A heuristic feature cluster search algorithm for precise functional brain mapping

Asadi, N.; Wang, Y.; Olson, I.; Obradovic, Z.

10.1101/518480 — neuroscience — Posted on 2019-01-11

2049 Dissecting the neural focus of attention reveals distinct processes for spatial attention and object-based storage in visual working memory

Hakim, N.; Adam, K. C. S.; Gunseli, E.; Awh, E.; Vogel, E. K.

10.1101/347518 — neuroscience — Posted on 2019-01-11

2050 Tumor mutational landscape is a record of the pre-malignant state

Kübler, K.; Karlic, R.; Haradhvala, N. J.; Ha, K.; Kim, J.; Kuzman, M.; Jiao, W.; Gakkhar, S.; Mouw, K. W.; Braunstein, L. Z.; Elemento, O.; Biankin, A. V.; Rooman, I.; Miller, M.; Karthaus, W. R.; Nogiec, C. D.; Juvenson, E.; Curry, E.; Mino-Kenudson, M.; Ellisen, L. W.; Brown, R.; Gusev, A.; Tomasetti, C.; Lolkema, M. P.; Steeghs, N.; van Herpen, C.; Kim, H.-G.; Lee, H.; Vlahovicek, K.; Bernstein, B. E.; Sawyers, C. L.; Hoadley, K. A.; Cuppen, E.; Koren, A.; Arndt, P. F.; Louis, D. N.; Stein, L. D.; Foulkes, W. D.; Polak, P.; Getz, G.

10.1101/517565 — genomics — Posted on 2019-01-11

2051 Mutation Of MLH3 Endonuclease Motif Reveals Integration Between Crossover Pathways In Mammalian Meiosis

Toledo, M.; Sun, X.; Brieno-Enriquez, M. A.; Raghavan, V.; Gray, S.; Pea, J.; Venkatesh, A.; Patel, L.; Borst, P. L.; Alani, E.; Cohen, P. E.

10.1101/517748 — genetics — Posted on 2019-01-11

2052 Cleaning genotype data from Diversity Outbred mice

Broman, K. W.; Gatti, D. M.; Svenson, K. L.; Sen, S.; Churchill, G. A.

10.1101/518308 — genetics — Posted on 2019-01-11

2053 Molecular evolution across developmental time reveals rapid divergence in early embryogenesis

Cutter, A. D.; Garrett, R. H.; Mark, S.; Wang, W.; Sun, L.

10.1101/518621 — evolutionary biology — Posted on 2019-01-11

2054 Homologous recombination substantially delays sequence but not gene content divergence of prokaryotic populations

Iranzo, J.; Wolf, Y. I.; Koonin, E. V.; Sela, I.

10.1101/518852 — evolutionary biology — Posted on 2019-01-11

2055 Pou5f3, SoxB1 and Nanog remodel chromatin on High Nucleosome Affinity Regions at Zygotic Genome Activation

Veil, M.; Yampolsky, L.; Gruening, B.; Onichtchouk, D.

10.1101/344168 — developmental biology — Posted on 2019-01-11

2056 Data-driven robust detection of tissue/cell-specific markers

Chen, L.; Herrington, D.; Clarke, R.; Yu, G.; Wang, Y.

10.1101/517961 — bioinformatics — Posted on 2019-01-11

2057 Syntrophic co-culture amplification of production phenotype for high-throughput screening of microbial strain libraries

Saleski, T.; Kerner, A.; Chung, M. T.; Jackman, C.; Khasbaatar, A.; Kurabayashi, K.; Lin, X. N.

10.1101/518639 — synthetic biology — Posted on 2019-01-11

2058 BDNF/TrkB.T1 signaling is a novel mechanism for astrocyte morphological maturation

Holt, L. M.; Pacheco, N. L.; Hernandez, R.; Hossain, M.; Olsen, M. L.

10.1101/518787 — neuroscience — Posted on 2019-01-11

2059 MetFish: A Metabolomics Platform for Studying Microbial Communities in Chemically Extreme Environments

Xu, C.; Couvillion, S. P.; Sontag, R. L.; Isern, N. G.; Maezato, Y.; Lindemann, S. R.; Roy Chowdhury, T.; Zhao, R.; Morton, B. R.; Moore, R. J.; Jansson, J. K.; Bailey, V. L.; Mouser, P. J.; Romine, M. F.; Fredrickson, J. F.; Metz, T. O.

10.1101/518647 — microbiology — Posted on 2019-01-11

2060 Antibody-mediated immobilization of virions in mucus

Jensen, M.; Wang, Y.-Y.; Lai, S.; Forest, M. G.; McKinley, S. A.

10.1101/500538 — immunology — Posted on 2019-01-11

2061 Short Tandem Repeats Information in TCGA is Statistically Biased by Amplification

Jain, S.; Mazaheri, B.; Raviv, N.; Bruck, J.

10.1101/518878 — genomics — Posted on 2019-01-11

2062 Hunter-gatherer genomes reveal diverse demographic trajectories following the rise of farming in East Africa

Gopalan, S.; Berl, R. E. W.; Belbin, G.; Gignoux, C.; Feldman, M. W.; Hewlett, B. S.; Henn, B. M.

10.1101/517730 — genetics — Posted on 2019-01-11

2063 Exploring deep-time relationships between cultural and genetic evolution in Northeast Asia

Matsumae, H.; Savage, P. E.; Ranacher, P.; Blasi, D. E.; Currie, T. E.; Sato, T.; Tajima, A.; Brown, S.; Stoneking, M.; Shimizu, K. K. K.; Oota, H.; Bickel, B.

10.1101/513929 — evolutionary biology — Posted on 2019-01-11

2064 Evolution of the mating type locus with suppressed recombination

Hadjivasiliou, Z.; Pomiankowski, A.

10.1101/518654 — evolutionary biology — Posted on 2019-01-11

2065 Simulation of the mechanics of actin assembly during endocytosis in yeast

Nickaeen, M.; Berro, J.; Pollard, T. D.; Slepchenko, B. M.

10.1101/518423 — cell biology — Posted on 2019-01-11

2066 rEXPAR: an isothermal amplification scheme that is robust to autocatalytic parasites

Urtel, G.; Galas, J.-C.; Estevez-Torres, A.

10.1101/518118 — biochemistry — Posted on 2019-01-11

2067 Real-time Detection of Driver’s Movement Intention in Response to Traffic Lights

Khaliliardali, Z.; Chavarriaga, R.; Zhang, H.; Gheorghe, L. A.; Perdikis, S.; Millan, J. d. R.

10.1101/443390 — neuroscience — Posted on 2019-01-11

2068 BDNF controls neuropsychiatric manifestation via autophagic regulation of p62 and GABAA receptor trafficking

Tomoda, T.; Sumitomo, A.; Shukla, R.; Hirota-Tsuyada, Y.; Miyachi, H.; Oh, H.; French, L.; Sibille, E.

10.1101/334466 — neuroscience — Posted on 2019-01-11

2069 Diversity decoupled from sulfur isotope fractionation in a sulfate reducing microbial community

Colangelo, J.; Pelikan, C.; Herbold, C.; Altschuler, I.; Loy, A.; Whyte, L.; Wing, B.

10.1101/518837 — microbiology — Posted on 2019-01-11

2070 SGI-4 in monophasic Salmonella Typhimurium ST34 is a novel ICE that enhances resistance to copper

Branchu, P.; Charity, O. J.; Bawn, M.; Thilliez, G.; Dallman, T. J.; Petrovska, L.; Kingsley, R.

10.1101/518175 — microbiology — Posted on 2019-01-11

2071 Cancer Classification from Healthy DNA using Machine Learning

Jain, S.; Mazaheri, B.; Raviv, N.; Bruck, J.

10.1101/517839 — genomics — Posted on 2019-01-11

2072 A Note on Computing Interval Overlap Statistics

Sarmashghi, S.; Bafna, V.

10.1101/517987 — genomics — Posted on 2019-01-11

2073 Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses

Cuellar-Partida, G.; Lundberg, M.; Kho, P. F.; D'Urso, S.; Gutierrez-Mondragon, L. F.; Hwang, L.-D.

10.1101/518027 — genetics — Posted on 2019-01-11

2074 Integrating past, present and future wheat research with Pretzel

Keeble-Gagnere, G.; Isdale, D.; Suchecki, R.; Kruger, A.; Lomas, K.; Carroll, D.; Li, S.; Whan, A.; Hayden, M.; Tibbits, J.

10.1101/517953 — bioinformatics — Posted on 2019-01-11

2075 The Ptr1 locus of Solanum lycopersicoides confers resistance to race 1 strains of Pseudomonas syringae pv. tomato and to Ralstonia pseudosolanacearum by recognizing the type III effectors AvrRpt2/RipBN

Mazo-Molina, C.; Mainiero, S.; Hind, S. R.; Kraus, C. M.; Vachev, M.; Maviane Macia, F.; Lindeberg, M.; Saha, S.; Strickler, S. R.; Feder, A.; Giovannoni, J. J.; Smart, C. D.; Peeters, N.; Martin, G. B.

10.1101/518399 — plant biology — Posted on 2019-01-11

2076 How to test for oscillatory modulation of neural function and behaviour

Zoefel, B.; Davis, M. H.; Riecke, L.

10.1101/517243 — neuroscience — Posted on 2019-01-11

2077 Optogenetic entrainment of the septo-hippocampal circuit is state conditional and attenuates spatial accuracy

Mouchati, P. R.; Holmes, G. L.; Kloc, M. L.; Barry, J. M.

10.1101/392050 — neuroscience — Posted on 2019-01-11

2078 Variability in Sensory Sensitivity Predicts Motion Sickness in Virtual Reality

Fulvio, J. M.; Ji, M.; Rokers, B.

10.1101/488817 — neuroscience — Posted on 2019-01-11

2079 General Functional Connectivity: shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks

Elliott, M. L.; Knodt, A. R.; Cooke, M.; Kim, M. J.; Melzer, T. R.; Keenan, R.; Ireland, D.; Ramrakha, S.; Poulton, R.; Caspi, A.; Moffitt, T. E.; Hariri, A. R.

10.1101/330530 — neuroscience — Posted on 2019-01-11

2080 Inflammation and matrix metalloproteinase 9 (Mmp-9) regulate photoreceptor regeneration in the adult zebrafish

Silva, N. J.; Nagashima, M.; Li, J.; Kakuk-Atkins, L.; Ashrafzadeh, M.; Hyde, D. R.; Hitchcock, P. F.

10.1101/518365 — neuroscience — Posted on 2019-01-11

2081 Noninvasive sleep monitoring in large-scale screening of knock-out mice reveals novel sleep-related genes

Joshi, S. S.; Sethi, M.; Striz, M.; Cole, N.; Denegre, J. M.; Ryan, J.; Lhamon, M. E.; Agarwal, A.; Murray, S.; Braun, R. E.; Fardo, D. W.; Kumar, V.; Donohue, K. D.; Sunderam, S.; Chesler, E. J.; Svenson, K. L.; O'Hara, B. F.

10.1101/517680 — neuroscience — Posted on 2019-01-11

2082 Defining and Evaluating Microbial Contributions to Metabolite Variation in Microbiome-Metabolome Association Studies

Noecker, C.; Chiu, H.-C.; McNally, C. P.; Borenstein, E.

10.1101/402040 — microbiology — Posted on 2019-01-11

2083 Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches.

Carter, J.; Walker, T. M.; Walker, A. S.; Whitfield, M.; Peto, T. E.; Crook, D. W.; Fowler, P. W.

10.1101/518142 — microbiology — Posted on 2019-01-11

2084 IFITM3 protects the heart during influenza virus infection

Kenney, A.; McMichael, T. M.; Imas, A.; Chesarino, N. M.; Zhang, L.; Dorn, L. E.; Wu, Q.; Alfaour, O.; Amari, F.; Chen, M.; Zani, A.; Chemudupati, M.; Accornero, F.; Coppola, V.; Rajaram, M. V. S.; Yount, J. S.

10.1101/518548 — immunology — Posted on 2019-01-11

2085 Genetic association analyses highlight IL6, ALPL, and NAV1 as three new susceptibility genes underlying calcific aortic valve stenosis

10.1101/515494 — genomics — Posted on 2019-01-11

2086 Efficient estimation and applications of cross-validated genetic predictions

Mefford, J. A.; Park, D.; Zheng, Z.; Ko, A.; Ala-Korpela, M.; Laakso, M.; Pajukanta, P.; Yang, J.; Witte, J.; Zaitlen, N.

10.1101/517821 — genetics — Posted on 2019-01-11

2087 qgg: an R package for large-scale quantitative genetic analyses

Rohde, P. D.; Sorensen, I. F.; Sorensen, P.

10.1101/503631 — genetics — Posted on 2019-01-11

2088 Mean-field computational approach to HIV dynamics on a fitness landscape

Chen, H.; Kardar, M.

10.1101/518704 — evolutionary biology — Posted on 2019-01-11

2089 Maternal investment, life histories, and the evolution of brain structure in primates

Powell, L. E.; Street, S. E.; Barton, R. A.

10.1101/513051 — evolutionary biology — Posted on 2019-01-11

2090 The impact of isoniazid preventive therapy on tuberculosis among household contacts of isoniazid-resistant patients.

Huang, C.-C.; Becerra, M. C.; Calderon, R.; Contreras, C.; Galea, J.; Grandjean, L.; Lecca, L.; Yataco, R.; Zhang, Z.; Murray, M.

10.1101/479865 — epidemiology — Posted on 2019-01-11

2091 zGrad: A nanobody-based degron system to inactivate proteins in zebrafish

Yamaguchi, N.; Colak-Champollion, T.; Knaut, H.

10.1101/518944 — developmental biology — Posted on 2019-01-11

2092 Neuroendocrine negative SCLC is mostly RB1 WT and may be sensitive to CDK4/6 inhibition

Sonkin, D.; Vural, S.; Thomas, A.; Teicher, B. A.

10.1101/516351 — cancer biology — Posted on 2019-01-11

2093 Ion counting demonstrates a high electrostatic potential of the nucleosome

Gebala, M.; Johnson, S.; Narlikar, G.; Herschlag, D.

10.1101/514471 — biophysics — Posted on 2019-01-11

2094 Discovering Data Access and Use Requirements Using the Data Tags Suite (DATS) Model

Alter, G.; Gonzalez-Beltran, A.; Ohno-Machado, L.; Rocca-Serra, P.

10.1101/518571 — bioinformatics — Posted on 2019-01-11

2095 Loss of a glutaredoxin gene underlies parallel evolution of trichome patter in Antirrhinum

Tan, Y.; Barnbrook, M.; Wilson, Y.; Molnar, A.; Hudson, A.

10.1101/518183 — plant biology — Posted on 2019-01-11

2096 Bacterially produced spermidine induces plant systemic susceptibility to pathogens

Melnyk, R. A.; Beskrovnaya, P. A.; Liu, Z.; Song, Y.; Haney, C. H.

10.1101/517870 — plant biology — Posted on 2019-01-11

2097 Acoustic and visual stimulus parameters underlying sound-symbolic crossmodal correspondences

List, S. M.; McCormick, K.; Lacey, S.; Nygaard, L. C.; Sathian, K.

10.1101/517581 — neuroscience — Posted on 2019-01-11

2098 Serotonergic Psychedelics LSD & Psilocybin Increase theFractal Dimension of Cortical Brain Activity in Spatial and Temporal Domains

Varley, T.; Carhart-Harris, R.; Roseman, L.; Menon, D.; Stamatakis, E.

10.1101/517847 — neuroscience — Posted on 2019-01-11

2099 Attention differentially modulates the amplitude of resonance frequencies in the visual cortex

Gulbinaite, R.; Roozendaal, D. H. M.; VanRullen, R.

10.1101/518779 — neuroscience — Posted on 2019-01-11

2100 Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

Burmistrova, O.; Olias-Arjona, A.; Eremeeva, T.; Shishov, D.; Zakurdaeva, K.; Almeida, A.; fedichev, p. O.; Bolaños, J. P.

10.1101/518092 — neuroscience — Posted on 2019-01-11

2101 Splicing factor Rbm10 facilitates heterochromatin assembly in fission yeast

Martina Weigt, M.; Gao, Q.; Ban, H.; he, H.; Mastrobuoni, G.; Kempa, S.; Chen, W.; Li, F.

10.1101/518936 — molecular biology — Posted on 2019-01-11

2102 DOT1L suppresses nuclear RNAi originating from enhancer elements in Caenorhabditis elegans

Esse, R.; Gushchanskaia, E.; Lord, A.; Grishok, A.

10.1101/320465 — genomics — Posted on 2019-01-11

2103 Recent origin of an XX/XY sex-determination system in the ancient plant lineage Ginkgo biloba

Zhang, H.; Zhang, R.; Yang, X.; Gu, K.-J.; Chen, W.; Chang, Y.; Xu, Q.; Liu, Q.; Qin, Y.; Hong, X.; Yin, P.-P.; Seim, I.; Lin, H.-Y.; Li, W.-H.; Tian, J.; Li, S.; Liu, L.; Liu, J.; Liu, S.; Su, X.; Wang, C.; Zhang, F.-M.; Ge, S.; Fu, C.-X.; Lee, S. M.-Y.; Xia, Y.; Wang, J.; Yang, H.; Fan, G.; Xu, X.; Zhao, Y.-P.; Liu, X.

10.1101/517946 — evolutionary biology — Posted on 2019-01-11

2104 Species dynamics and interactions via metabolically informed consumer-resource models

Muscarella, M. E.; O'Dwyer, J. P.

10.1101/518449 — ecology — Posted on 2019-01-11

2105 Kin-dependent dispersal influences relatedness and genetic structuring in a lek system

Cayuela, H.; Boualit, L.; Laporte, M.; Prunier, J. G.; Preiss, F.; Laurent, A.; Foletti, F.; Clobert, J.; Jacob, G.

10.1101/518829 — ecology — Posted on 2019-01-11

2106 Drug Recommendation toward Safe Polypharmacy

Chiang, W.-H.; Ning, X.

10.1101/518415 — bioinformatics — Posted on 2019-01-11

2107 Alterations in ion channel expression surrounding implanted microelectrode arrays in the brain

Salatino, J. W.; Kale, A. P.; Purcell, E. K.

10.1101/518811 — bioengineering — Posted on 2019-01-11

2108 The visual social environment affects non-additively neighbor spacing and interaction time in zebrafish

Pita, D.; Fernandez-Juricic, E.

10.1101/511972 — animal behavior and cognition — Posted on 2019-01-11

2109 Phosphorylation of the exocyst subunit Exo70B2 contributes to the regulation of its function

Teh, O.-K.; Lee, C.-W.; Ditengou, F. A.; Klecker, T.; Furlan, G.; Zietz, M.; Hause, G.; Eschen-Lippold, L.; Hoehenwarter, W.; Lee, J.; Ott, T.; Trujillo, M.

10.1101/266171 — cell biology — Posted on 2019-01-11

2110 Interactions between Viperin, IRAK1 and TRAF6 couple innate immune signaling to antiviral ribonucleotide synthesis

Dumbrepatil, A. B.; Ghosh, S.; Patel, A. M.; Malec, P. A.; Zegalia, K.; Hoff, J. D.; Kennedy, R. T.; Marsh, E. N. G.

10.1101/318840 — biochemistry — Posted on 2019-01-11

2111 Loss of YAP/TAZ impaired the proliferation and differentiation ability of neural progenitor cells

Kong, S.; Rock, C. O.; Cao, X.

10.1101/296053 — neuroscience — Posted on 2019-01-11

2112 Delta/Notch signaling controls neuroepithelial morphogenesis in the zebrafish spinal cord

Sharma, P.; Saraswathy, V. M.; Xiang, L.; Furthauer, M.

10.1101/517714 — developmental biology — Posted on 2019-01-11

2113 Cell Fate Determining Molecular Switches and Signaling Pathway in Pax7-expressing Somitic Mesoderm

Fung, C. W.; Han, Z.; Zhou, S.; Wu, Z.; Wu, A. R.

10.1101/518084 — developmental biology — Posted on 2019-01-11

2114 The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells

Corn, J. E.; Kabir, S.; Cidado, J.; Andersen, C.; Dick, C.; Lin, P.-C.; Mitros, T.; Ma, H.; Baik, S. H.; Belmonte, M.; Drew, L.

10.1101/518555 — cancer biology — Posted on 2019-01-11

2115 Coupling of ATPase activity, microtubule binding and mechanics in the dynein motor domain

Niekamp, S.; Coudray, N.; Zhang, N.; Vale, R. D.; Bhabha, G.

10.1101/309179 — biochemistry — Posted on 2019-01-11

2116 Iron-sequestering nanocompartments as multiplexed Electron Microscopy gene reporters

Sigmund, F.; Pettinger, S.; Kube, M.; Schneider, F.; Schifferer, M.; Aichler, M.; Schneider, S.; Walch, A.; Misgeld, T.; Dietz, H.; Westmeyer, G. G.

10.1101/516955 — synthetic biology — Posted on 2019-01-11

2117 Childhood urbanization affects prefrontal cortical responses to trait anxiety and interacts with polygenic risk for depression

Zhang, X.; Yan, H.; Yu, H.; Zhao, X.; Shah, S.; Dong, Z.; Yang, G.; Zhang, X.; Chen, Q.; Li, J.; Jiang, S.; Muse, T.; Liao, J.; Zhang, Y.; Yue, W.; Weinberger, D. R.; Zhang, D.; Tan, H. Y.

10.1101/246876 — neuroscience — Posted on 2019-01-11

2118 iPSC-derived Cancer Organoids Recapitulate Genomic and Phenotypic Alterations of c-met-mutated Hereditary Kidney Cancer

Hwang, J. W.; Desterke, C.; Feraud, O.; Richard, S.; Ferlicot, S.; Verkarre, V.; Patard, J. J.; Loisel-Duwattez, J.; Foudi, A.; Griscelli, F.; Bennaceur Griscelli, A.; Turhan, A. G.

10.1101/518456 — cancer biology — Posted on 2019-01-11

2119 Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-Statistics with Peptide Quantification Concordance

Peshkin, L.; Gupta, M.; Ryazanova, L.; Wuhr, M.

10.1101/210476 — systems biology — Posted on 2019-01-11

2120 In vitro synergy between Sodium Deoxycholate and Furazolidone against Enterobacteria via Inhibition of Multidrug Efflux Pumps

Le, V. V. H.; Olivera, C.; Spagnuolo, J.; Davies, I.; Rakonjac, J.

10.1101/518050 — microbiology — Posted on 2019-01-11

2121 Methylation and Gene Expression Differences Between Reproductive Castes of Bumblebee Workers.

Marshall, H.; Lonsdale, Z. N.; Mallon, E. B.

10.1101/517698 — evolutionary biology — Posted on 2019-01-11

2122 Guanine content of microRNAs is associated with their tumor suppressive and oncogenic roles in lung and breast cancers

Cohen, A.; Burgos-Aceves, M. A.; Smith, Y.

10.1101/518472 — cancer biology — Posted on 2019-01-11

2123 Deep neural networks for interpreting RNA binding protein target preferences

Ghanbari, M.; Ohler, U.

10.1101/518191 — bioinformatics — Posted on 2019-01-11

2124 Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

Manzo, E.; Lorenzini, I.; Barrameda, D.; O'Conner, A. G.; Barrows, J. M.; Starr, A.; Kovalik, T.; Shreiner, D. D.; Joardar, A.; Lievens, J.-C.; Bowser, R.; Sattler, R.; Zarnescu, D.

10.1101/517649 — neuroscience — Posted on 2019-01-11

2125 Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis

Sasanuma, H.; Sakurai, H. S. M.; Furihata, Y.; Challa, K.; Palmer, L.; Gasser, S. M.; Shinohara, M.; Shinohara, A.

10.1101/518035 — genetics — Posted on 2019-01-11

2126 In Vivo Monitoring of Rare Circulating Tumor Cell and Cluster Dissemination in a Multiple Myeloma Xenograft Model

Patil, R.; Tan, X.; Bartosik, P.; Detappe, A.; Runnels, J. M.; Ghobrial, I. M.; Lin, C. P.; Niedre, M.

10.1101/516641 — bioengineering — Posted on 2019-01-11

2127 Network-targeted, multi-site direct cortical stimulation enhances working memory by modulating phase lag of low frequency oscillations

Alagapan, S.; Riddle, J.; Huang, W. A.; Hadar, E.; Shin, H. W.; Frohlich, F.

10.1101/514554 — neuroscience — Posted on 2019-01-11

2128 Topoisomerase 2-dependent nuclear DNA damage shapes extracellular growth factor responses through AKT phosphorylation dynamics to control virus latency

Hu, H.-L.; Schiflett, L. A.; Kobayashi, M.; Chao, M. V.; Wilson, A. C.; Mohr, I.; Huang, T. T.

10.1101/518373 — molecular biology — Posted on 2019-01-11

2129 Gene activation by a CRISPR-assistant trans enhancer

Xu, X.; Dai, W.; Wang, D.; Wu, J.; Wang, J.

10.1101/517920 — biochemistry — Posted on 2019-01-11

2130 Structural basis for functional interactions in dimers of SLC26 transporters

Chang, Y.-N.; Jaumann, E. A.; Reichel, K.; Hartmann, J.; Oliver, D.; Hummer, G.; Joseph, B.; Geertsma, E.

10.1101/518209 — biochemistry — Posted on 2019-01-11

2131 Low-dose IFN-γ induces tumor cell stemness in tumor microenvironment of non-small cell lung cancer

Zhang, Y.; Song, M.; Ping, Y.; Zhang, K.; Yang, L.; Li, F.; Cheng, S.; Yue, D.; Maimela, N. R.; Qu, J.; Liu, S.; Sun, T.; Li, Z.; Xia, J.; Zhang, B.; Wang, L.

10.1101/517003 — cancer biology — Posted on 2019-01-11

2132 Most of the deregulated CpG-island-controlled genes in glioma do not show DNA methylation defects

Arnaud, P.; Court, F.; Le Boiteux, E.; Fogli, A.; Müller-Barthelemy, M.; Vaurs-Barriere, C.; Chautard, E.; Pereira, B.; Biau, J.; Kemeny, J.-L.; Khalil, T.; Karayan-Tapon, L.; Verrelle, P.

10.1101/516997 — molecular biology — Posted on 2019-01-11

2133 Colistin heteroresistance in Enterobacter cloacae is mediated by PmrAB-independent 4-amino-4-deoxy-l-arabinose addition to lipid A

Kang, K. N.; Klein, D. R.; Kazi, M. I.; Guerin, F.; Cattoir, V.; Brodbelt, J. S.; Boll, J. M.

10.1101/516872 — microbiology — Posted on 2019-01-11

2134 Control of Staphylococcus aureus quorum sensing by a membrane-embedded peptidase

Cosgriff, C. J.; White, C. R.; Teoh, W. P.; Grayczyk, J. P.; Alonzo, F.

10.1101/516906 — microbiology — Posted on 2019-01-11

2135 Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

Powers, R. K.; Sullivan, K. D.; Culp-Hill, R.; Ludwig, M. P.; Smith, K. P.; Waugh, K. A.; Minter, R.; Tuttle, K. D.; Lewis, H. C.; Rachubinski, A. L.; Granrath, R. E.; Wilkerson, R. B.; Kahn, D. E.; Joshi, M.; D'Alessandro, A.; Costello, J. C.; Espinosa, J. M.

10.1101/403642 — physiology — Posted on 2019-01-11

2136 CIC-DUX4 expression drives the development of small round cell sarcoma in transgenic zebrafish: a new model revealing a role for ETV4 in CIC-mediated sarcomagenesis

Watson, S.; Kendall, G. C.; Rakheja, D.; McFaul, M. E.; Draper, B. W.; Tirode, F.; Delattre, O.; Amatruda, J. F.

10.1101/517722 — cancer biology — Posted on 2019-01-11

2137 Targeted antifungal liposomes

Ambati, S.; Ferraro, A. R.; Kang, S. E.; Lin, X.; Momany, M.; Lewis, Z. A.; Meagher, R. B.

10.1101/518043 — molecular biology — Posted on 2019-01-11

2138 Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.

Baker, A. T.; Greenshields-Watson, A.; Coughlan, L.; Davies, J. A.; Uusi-Kerttula, H.; Cole, D. K.; Rizkallah, P. J.; Parker, A. L.

10.1101/406819 — microbiology — Posted on 2019-01-11

2139 RBM10 variants and RBM5 involve in alternative splicing of RBM10v1 pre-mRNA: RBM10v1 includes its own exon 4, but RBM10v2 and RBM5 skip it.

Nishio, K.

10.1101/516930 — cancer biology — Posted on 2019-01-11

2140 Stochastic neural field model of stimulus-dependent variability in cortical neurons

Bressloff, P. C.

10.1101/514315 — neuroscience — Posted on 2019-01-11

2141 From individuals to populations: How intraspecific competition shapes thermal reaction norms

Mallard, F.; Le Bourlot, V.; Le Coeur, C.; Peronnet, R.; Avnaim, M.; Claessen, D.; Tully, T.

10.1101/513739 — ecology — Posted on 2019-01-11

2142 Discovery of Alstrom syndrome gene as a regulator of centrosome duplication in asymmetrically dividing stem cells in Drosophila.

Chen, C.; Yamashita, Y.

10.1101/490615 — developmental biology — Posted on 2019-01-11

2143 Stochastic bacterial population dynamics prevent the emergence of antibiotic resistance

Alexander, H. K.; MacLean, C.

10.1101/458547 — microbiology — Posted on 2019-01-11

2144 Drosophila ClC-a is required in glia of the stem cell niche for proper neurogenic proliferation and wiring of neural circuits

Plazaola-Sasieta, H.; Zhu, Q.; Gaitan-Penas, H.; Rios, M.; Estevez, R.; Morey, M.

10.1101/482778 — developmental biology — Posted on 2019-01-11

2145 Genome-wide Prediction of Potential Polycomb Response Elements and their Functions

Khabiri, M.; Freddolino, P. L.

10.1101/516500 — systems biology — Posted on 2019-01-11

2146 Electrochemotherapy with bleomycin associated with doxorubicin induces tumor regression and decreases the proliferative index in canine cutaneous squamous cell carcinomas

Anjos, D. S.; Bueno, C.; Magalhaes, L. F.; Magalhaes, G. M.; Mattos-Junior, E.; Rodrigues, M. M. P.; De Nardi, A. B.; Brunner, C.; Leis-Filho, A. F.; Calazans, S. G.; Fonseca-Alves, C. E.

10.1101/474262 — cancer biology — Posted on 2019-01-11

2147 High-order theta harmonics account for the detection of slow gamma

Zhou, Y.; Sheremet, A.; Qin, Y.; Kennedy, J. P.; DiCola, N. M.; Maurer, A. P.

10.1101/428490 — neuroscience — Posted on 2019-01-11

2148 GADMA: Genetic algorithm for inferring demographic history of multiple populations from allele frequency spectrum data

Noskova, E.; Ulyantsev, V.; Koepfli, K.-P.; O'Brien, S. J.; Dobrynin, P.

10.1101/407734 — evolutionary biology — Posted on 2019-01-11

2149 The Relationship between Parasitic Fleas and Small Mammals in Household of Western Yunnan Province, China

Yin, J.-X.; Cheng, X.-O.; Zhao, Q.-F.; Wei, Z.-F.; Xu, D.-D.; Wang, M.-D.; Zhou, Y.; Wang, X.-F.; Liu, Z.-X.

10.1101/518266 — zoology — Posted on 2019-01-11

2150 E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1

Drews, C.; Case, S.; Vande Pol, S.

10.1101/518282 — microbiology — Posted on 2019-01-11

2151 Why cooperation is not running away

Geoffroy, F.; Baumard, N.; Andre, J.-B.

10.1101/316117 — evolutionary biology — Posted on 2019-01-11

2152 Epidemic foci of hemorrhagic fever with renal syndrome in Shandong Province, China, based on patients, rodents and molecular epidemiology characteristics, 2012-2015

Zheng, Z.; Wang, P.; Wang, Z.; Zhang, D.; Wang, X.; Zuo, S.; Li, X.

10.1101/518274 — epidemiology — Posted on 2019-01-11

2153 Biological Sequence Modeling with Convolutional Kernel Networks

Chen, D.; Jacob, L.; Mairal, J.

10.1101/217257 — bioinformatics — Posted on 2019-01-11

2154 Economic Burden of Hypoglycaemia among Type II Diabetes Mellitus Patients in Malaysia.

Aljunid, S. M.; Yin, A. N.; Ismail, A.; Abdul Rashid, S. A. Z.; Nur, A. M.; Cheah, J.; Matzen, P.

10.1101/518225 — scientific communication and education — Posted on 2019-01-11

2155 Optogenetic entrainment of the septo-hippocampal circuit is state conditional and attenuates spatial accuracy

Mouchait, P. R.; Holmes, G. L.; Kloc, M. L.; Barry, J. M.

10.1101/392050 — neuroscience — Posted on 2019-01-10

2156 Dimensions of neighborhood tracts and their associations with mental health problems

Forthman, K. L.; Yeh, H.-w.; Kuplicki, R.; Paulus, M. P.

10.1101/518258 — neuroscience — Posted on 2019-01-11

2157 The semantic segmentation approach for normal and pathologic tympanic membrane using deep learning

Seok, J.; Song, J.-J.; Koo, J.-W.; Hee Chan, K.; Choi, B. Y.

10.1101/515007 — bioinformatics — Posted on 2019-01-10

2158 A substrate for modular, extensible data-visualization

Matelsky, J. K.; Downs, J.; Cowley, H.; Wester, B.; Gray-Roncal, W.

10.1101/217349 — bioinformatics — Posted on 2019-01-10

2159 Reversible silencing of endogenous receptors in intact brain tissue using two-photon pharmacology

Pittolo, S.; Lee, H.; Llado, A.; Tosi, S.; Bosch, M.; Bardia, L.; Gomez-Santacana, X.; Llebaria, A.; Soriano, E.; Colombelli, J.; Poskanzer, K. E.; Perea, G.; Gorostiza, P.

10.1101/515288 — pharmacology and toxicology — Posted on 2019-01-10

2160 Eco-evolutionary community turnover following environmental change

Lasky, J. R.

10.1101/285288 — evolutionary biology — Posted on 2019-01-10

2161 Neural sensitization improves encoding fidelity in the primate retina

Appleby, T. R.; Manookin, M. B.

10.1101/482190 — neuroscience — Posted on 2019-01-10

2162 Functional characterization of Komagataella phaffii centromeres by a color-based plasmid stability assay

Piva, L. C.; De Marco, J.; Moraes, L.; Reis, V.; Torres, F. A. G.

10.1101/433417 — molecular biology — Posted on 2019-01-10

2163 Dissociable electrophysiological correlates of semantic access of motor and non-motor concepts

Sokoliuk, R.; Calzolari, S.; Cruse, D.

10.1101/517284 — neuroscience — Posted on 2019-01-10

2164 Diversity, biogeography, and evidence for endemism of SAR11 bacteria from the Arctic Ocean

Kraemer, S.; Ramachandran, A.; Colatriano, D.; Lovejoy, C.; Walsh, D.

10.1101/517433 — microbiology — Posted on 2019-01-10

2165 Female lower urinary tract microbiota do not correspond to IC/PBS symptoms: a case-controlled study

Bresler, L.; Price, T. K.; Tulke, M.; Hilt, E. E.; Joyce, C.; Fitzgerald, C.; Wolfe, A. J.

10.1101/517557 — microbiology — Posted on 2019-01-10

2166 Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome

Talkish, J.; Igel, H.; Perriman, R. J.; Shiue, L.; Katzman, S.; Munding, E. M.; Shelansky, R.; Donohue, J. P.; Ares, M.

10.1101/515197 — genomics — Posted on 2019-01-10

2167 The client-binding domain of the cochaperone SGTA/Sgt2 has a helical-hand structure that binds a short hydrophobic helix

Lin, K.-F.; Fry, M. Y.; Saladi, S.; Clemons, W. M.

10.1101/517573 — biochemistry — Posted on 2019-01-10

2168 Stem-cell-ubiquitous genes spatiotemporally coordinate division through regulation of stem-cell-specific gene networks

Clark, N. M.; Buckner, E.; Fisher, A. P.; Nelson, E. C.; Nguyen, T. T.; Simmons, A. R.; de Luis Balaguer, M. A.; Butler-Smith, T.; Sheldon, P. J.; Bergmann, D. C.; Williams, C. M.; Sozzani, R.

10.1101/517250 — systems biology — Posted on 2019-01-10

2169 Natural variation for unusual host responses and flagellin-mediated immunity against Pseudomonas syringae in genetically diverse tomato accessions

Roberts, R.; Mainiero, S.; Powell, A. F.; Liu, A. E.; Shi, K.; Hind, S. R.; Strickler, S. R.; Collmer, A.; Martin, G. B.

10.1101/516617 — plant biology — Posted on 2019-01-10

2170 The time-course of component processes of selective attention

Wen, T.; Duncan, J.; Mitchell, D. J.

10.1101/511022 — neuroscience — Posted on 2019-01-10

2171 Seasonal and directional dispersal behavior in an ongoing dove invasion

Slager, D. L.

10.1101/517540 — ecology — Posted on 2019-01-10

2172 Hierarchical Patient-centric Caregiver Network Method for Clinical Outcomes Study

Park, Y.; Karampourniotis, P.; Sylla, I.; Das, A. K.

10.1101/388066 — bioinformatics — Posted on 2019-01-10

2173 Building a botanical foundation for perennial agriculture: Global inventory of wild, perennial herbaceous Fabaceae species

Ciotir, C.; Applequist, W.; Crews, T. E.; Cristea, N.; DeHaan, L. R.; Frawley, E.; Herron, S. A.; Magill, R.; Miller, J. S.; Roskov, Y.; Schlautman, B.; Solomon, J. C.; Townesmith, A.; Van Tassel, D.; Zarucchi, J. L.; Miller, A.

10.1101/515189 — evolutionary biology — Posted on 2019-01-10

2174 Lactate and glycerol-3-phosphate metabolism cooperatively regulate growth and redox balance during Drosophila melanogaster larval development

Li, H.; Buddika, K.; Sterrett, M. C.; Julick, C. R.; Pletcher, R. C.; Gosney, C. J.; Burton, A. K.; Karty, J. A.; Montooth, K. L.; Sokol, N. S.; Tennessen, J. M.

10.1101/517532 — developmental biology — Posted on 2019-01-10

2175 A novel role for the tumor suppressor gene ITF2 in lung tumorigenesis through the action of Wnt signaling pathway

Pernia, O.; Sastre-Perona, A.; Rodriguez-Antolin, C.; Garcia-Guede, A.; Palomares-Bralo, M.; Rosas, R.; Sanchez-Cabrero, D.; Rodriguez, C.; Martin-Arenas, R.; Pulido, V.; de Castro, J.; Santisteban, P.; Vera, O.; Ibanez de Caceres, I.

10.1101/517169 — cancer biology — Posted on 2019-01-10

2176 The effects of a TMS double lesion to a cortical network

Cameron, I.; Cretu, A.; Struik, F.; Toni, I.

10.1101/517128 — neuroscience — Posted on 2019-01-10

2177 A Domain-general Cognitive Core defined in Multimodally Parcellated Human Cortex

Assem, M.; Glasser, M. F.; Van Essen, D. C.; Duncan, J.

10.1101/517599 — neuroscience — Posted on 2019-01-10

2178 Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess -Synuclein at Synapses

Banks, S. M. L.; Medeiros, A. T.; McQuillan, M.; Busch, D. J.; Ibarraran-Viniegra, A. S.; Roy, S.; Sousa, R.; Lafer, E. M.; Morgan, J. R.

10.1101/517524 — neuroscience — Posted on 2019-01-10

2179 Extensive splicing across the Saccharomyces cerevisiae genome

Douglass, S.; Leung, C. S.; Johnson, T. L.

10.1101/515163 — molecular biology — Posted on 2019-01-10

2180 Bacterioplankton dynamics driven by inter-annual variation in phytoplankton spring bloom communities in the Baltic Sea

Camarena Gomez, M. T.; Ruiz-Gonzalez, C.; Piiparinen, J.; Lipsewers, T.; Sobrino, C.; Logares, R.; Spilling, K.

10.1101/513606 — microbiology — Posted on 2019-01-10

2181 A direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila

Uyehara, C. M.; McKay, D. J.

10.1101/517458 — developmental biology — Posted on 2019-01-10

2182 Oxidized products of α-linolenic acid negatively regulate cellular survival and motility of breast cancer cells

Gutierrez-Pajares, J. L.; Ben Hassen, C.; Oger, C.; Galano, J.-M.; Durand, T.; Frank, P. G.

10.1101/517094 — cancer biology — Posted on 2019-01-10

2183 A multi-reporter bacterial 2-hybrid assay for the fast, simple, and dynamic assay of PDZ domain - peptide interactions

Ichikawa, D. M.; Corbi, C.; Shen, M. J.; Snider, J.; Wong, V.; Stagljar, I.; Kim, P. M.; Noyes, M. B.

10.1101/512566 — synthetic biology — Posted on 2019-01-10

2184 Learning of pathogenic bacteria in adult C. elegans bidirectionally regulates pathogen response in the progeny

Pereira, A.; Gracida, X.; Kagias, K.; Zhang, Y.

10.1101/500264 — neuroscience — Posted on 2019-01-10

2185 On the evolutionary ecology of multidrug resistance in bacteria

Lehtinen, S.; Blanquart, F.; Lipsitch, M.; Fraser, C.; The Maela Pneumococcal Collaboration,

10.1101/233957 — evolutionary biology — Posted on 2019-01-10

2186 IMCC: Quantitative Analysis of the Inter-module Connectivity for Bio-network

Wang, P.; Liu, J.; Yu, Y.; Zhang, Y.; Li, B.; Li, D.; Xu, W.; Liu, Q.; Wang, Z.

10.1101/516237 — systems biology — Posted on 2019-01-10

2187 The persistent influence of caste on under-five mortality: Factors that explain the caste-based gap in high focus Indian states

Bora, J. K.; Raushan, R.; Lutz, W.

10.1101/516070 — epidemiology — Posted on 2019-01-10

2188 Assessment of the new World Health Organization’s dengue classification for predicting severity of illness and level of healthcare required

Ajlan, B. A.; Alafif, M. M.; Alawi, M. M.; Akbar, N. A.; Aldigs, E. K.; Madani, T. A.

10.1101/516229 — epidemiology — Posted on 2019-01-10

2189 Drinking earth for wine. Estimation of soil erosion in the Prosecco DOCG area (NE Italy), toward a soil footprint of bottled sparkling wine production

Pappalardo, S. E.; Gislimberti, L.; Ferrarese, F.; Adriano, G.; Ialina Charlotte, V.; Mozzi, P.; De Marchi, M.

10.1101/516245 — ecology — Posted on 2019-01-10

2190 Oxytocin promotes coordinated out-group attack during intergroup conflict in humans

Zhang, H.; Gross, J.; De Dreu, C.; Ma, Y.

10.1101/403790 — neuroscience — Posted on 2019-01-10

2191 A human ex vivo dengue virus neutralization assay identifies priority antibodies and epitopes for vaccines and therapeutics.

Vu, T.; Clapham, H.; Huynh, V.; Vo, L.; Le, D.; Vu, N.; Nguyen, G.; Huynh, T.; Duong, K.; Tran, V.; Huynh, H.; Huynh, T.; Nguyen, T.; Nguyen, N.; Luong, T.; Nguyen, P.; Nguyen, C.; Gough, G.; Wills, B.; Carrington, L.; Simmons, C.

10.1101/516195 — immunology — Posted on 2019-01-10

2192 Probing complexity of microalgae mixtures with novel spectral flow cytometry approach and \"virtual filtering\"

Barteneva, N. S.; Dashkova, V.; Vorobjev, I. A.

10.1101/516146 — ecology — Posted on 2019-01-10

2193 ATRAID, a genetic factor that regulates the action of nitrogen-containing bisphosphonates on bone.

Surface, L.; Park, J.; Kumar, S.; Burrow, D.; Lyu, C.; Li, J.; Song, N.; Yu, Z.; Rajagopal, A.; Bae, Y.; Lee, B.; Mumm, S.; Haller, G.; Gu, C.; Baker, J.; Mohseni, M.; Sum, M.; Huskey, M.; Duan, S.; Bijanki, V.; Civitelli, R.; Gardner, M.; McAndrew, C.; Ricci, W.; Gurnett, C.; Diemer, K.; Carette, J.; Varadarajan, M.; Brummelkamp, T.; Birsoy, K.; Sabatini, D.; Peterson, T.

10.1101/338350 — genomics — Posted on 2019-01-10

2194 When can we trust population trends? A method for quantifying the effects of sampling interval and duration

Wauchope, H. S.; Johnston, A.; Amano, T.; Sutherland, W. J.

10.1101/498170 — ecology — Posted on 2019-01-10

2195 Modeling impacts of climate change on the potential habitat of an endangered Brazilian endemic coral: discussion about deep sea refugia

Oliveira, U. D. R.; Lima, G. V.; Cordeiro, R. T.; Gomes, P. B.; PEREZ, C. D.

10.1101/517359 — ecology — Posted on 2019-01-10

2196 Osmoregulation of glutamine synthetase from Giant freshwater prawn (Macrobrachium rosenbergii) under osmotic stress

Zhijie, L.; Zhendong, Q.; Vijayaraman, S. B.; Chengkai, Y.; Guomao, S.; Jiabo, L.; Guang, Y.; Haiyang, S.; Gan, P.; Li, L.; Zhijie Lu, Zhendong Qin, Sarath Babu V, Chengkai Ye, Guomao Su, Jiabo Li, Guang Yang, Haiyang Shen,,

10.1101/517409 — physiology — Posted on 2019-01-10

2197 Inferring lifestyle for Aves and Theropoda: a model based on curvatures of extant avian ungual bones

Cobb, S. E.; Sellers, W. I.

10.1101/517375 — paleontology — Posted on 2019-01-10

2198 Comparison between diffusion MRI tractography and histological tract-tracing of cortico-cortical structural connectivity in the ferret brain

Delettre, C.; Messe, A.; Dell, L.-A.; Foubet, O.; Heuer, K.; Larrat, B.; Meriaux, S.; Mangin, J.-F.; Reillo, I.; de Juan Romero, C.; Borrell, V.; Toro, R.; Hilgetag, C. C.

10.1101/517136 — neuroscience — Posted on 2019-01-10

2199 Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics

Subramanian, A.; Sidhom, E.-H.; Emani, M.; Sahakian, N.; Vernon, K.; Zhou, Y.; Kost-Alimova, M.; Weins, A.; Slyper, M.; Waldman, J.; Dionne, D.; Nguyen, L.; Marshall, J. L.; Rozenblatt-Rosen, O.; Regev, A.; Greka, A.

10.1101/516807 — genomics — Posted on 2019-01-10

2200 Premeiotic and meiotic failures lead to hybrid male sterility in the Anopheles gambiae complex

Liang, J.; Sharakhov, I. V.

10.1101/507889 — evolutionary biology — Posted on 2019-01-10

2201 Competency assessment of the medical interns and nurses and prevailing practices to provide family planning services in teaching hospitals in three states of India.

Gupta, M.; Verma, M.; Kaur, K.; Iyengar, K. S.; Singh, T.; Singh, A.

10.1101/517326 — epidemiology — Posted on 2019-01-10

2202 Left Pulmonary Artery in 22q11.2 deletion syndrome. Echocardiographic evaluation in patients without cardiac defects and role of Tbx1 in mice.

Mastromoro, G.; Calcagni, G.; Versacci, P.; Putotto, C.; Chinali, M.; Lambiase, C.; Unolt, M.; Pelliccione, E.; Anaclerio, S.; Caprio, C.; Cioffi, S.; Bilio, M.; Baban, A.; Drago, F.; Digilio, M. C.; Marino, B.; Baldini, A.

10.1101/517342 — developmental biology — Posted on 2019-01-10

2203 Effects of daily L-dopa administration on learning and brain structure in older adults undergoing four weeks of cognitive training: a randomised, parallel-group, double-blind, placebo-controlled trial.

Lebedev, A. V.; Nilsson, J.; Lindstrom, J.; Fredborg, W.; Akenine, U.; Hillila, C.; Andersen, P.; Spulber, G.; de Lange, E. C.; van den Berg, D.-J.; Kivipelto, M.; Lovden, M.

10.1101/482679 — clinical trials — Posted on 2019-01-10

2204 Doublecotin-like kinase 1 increases chemoresistance of colorectal cancer cells through the anti-apoptosis pathway

Li, L.; Jones, K.; Mei, H.

10.1101/517425 — cancer biology — Posted on 2019-01-10

2205 A deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure

Trieu, T.; Khurana, E.

10.1101/516849 — bioinformatics — Posted on 2019-01-10

2206 Analysis of the risk and protective roles of work-related and individual variables in burnout syndrome in nurses

Perez-Fuentes, M. d. C.; Molero Jurado, M. d. M.; Martos Martinez, A.; Gazquez Linares, J. J.

10.1101/517383 — scientific communication and education — Posted on 2019-01-10

2207 Temperature dependence of allelopathy duality and its influence on boreal forest succession-A case analysis of Picea schrenkiana

ruan, x.; yang, l.; yu, m.-f.; li, z.-h.; zhao, Y.-x.; pan, c.-d.; jiang, d.-a.; wang, q.

10.1101/516823 — plant biology — Posted on 2019-01-10

2208 Live applications of norbormide-based fluorescent probes in Drosophila melanogaster

Forgiarini, A.; Wang, Z.; D'Amore, C.; Jay-Smith, M.; Li, F. F.; Hopkins, B.; Brimble, M. A.; Pagetta, A.; Bersani, S.; De Martin, S.; Napoli, B.; Bova, S.; Rennison, D.; Orso, G.

10.1101/517334 — pharmacology and toxicology — Posted on 2019-01-10

2209 Photoactivation of olfactory sensory neurons does not affect action potential conduction in individual trigeminal sensory axons innervating the rodent nasal cavity

Maurer, M.; Papotto, N.; Sertel-Nakajima, J.; Schueler, M.; Möhrlen, F.; Messlinger, K.; De Col, R.; Frings, S.; Carr, R. W.

10.1101/517391 — neuroscience — Posted on 2019-01-10

2210 B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma

Griss, J.; Bauer, W.; Wagner, C.; Maurer-Granofszky, M.; Simon, M.; Chen, M.; Steinberger, P.; Grabmeier-Pfistershammer, K.; Roka, F.; Penz, T.; Bock, C.; Zhang, G.; Herlyn, M.; Glatz, K.; Laubli, H.; Mertz, K. D.; Petzelbauer, P.; Wiesner, T.; Hartl, M.; Pickl, W.; Somasundaram, R.; Wagner, S. N.

10.1101/478735 — cancer biology — Posted on 2019-01-10

2211 Life on the margin: rainwater tanks facilitate overwintering of the dengue vector, Aedes aegypti, in a sub-tropical climate.

Trewin, B. J.; Darbro, J. M.; Zalucki, M. P.; Jansen, C. C.; Schellhorn, N. A.; Devine, G. J.

10.1101/517318 — zoology — Posted on 2019-01-10

2212 Analysis of Suicidal Patients Admitted to The Emergency Rooms and Their Intensive Care Requirements, A Double-Center Study in Turkey

kocamer simsek, b.; Sengül, K. S.

10.1101/517417 — neuroscience — Posted on 2019-01-10

2213 Attractor competition enriches cortical dynamics during awakening from anesthesia

Tort-Colet, N.; Capone, C.; Sanchez-Vives, M. V.; Mattia, M.

10.1101/517102 — neuroscience — Posted on 2019-01-10

2214 Selection and validation of reference genes for quantitative Real-Time PCR in Arabis alpina

Stephan, L.; Tilmes, V.; Hülskamp, M.

10.1101/517367 — molecular biology — Posted on 2019-01-10

2215 Genetic and environmental perturbations drive modular transcriptome responses

Mark, S.; Weiss, J.; Sharma, E.; Liu, T.; Wang, W.; Claycomb, J.; Cutter, A.

10.1101/517235 — genomics — Posted on 2019-01-10

2216 Evolutionary Dynamics Do Not Motivate a Single-Mutant Theory of Human Language

de Boer, B.; Thompson, B.; Ravignani, A.; Boeckx, C.

10.1101/517029 — evolutionary biology — Posted on 2019-01-10

2217 Aurora B-INCENP localization at centromeres/inner kinetochores is essential for chromosome bi-orientation in budding yeast

Garcia-Rodriguez, L. J.; Kasciukovic, T.; Denninger, V.; Tanaka, T. U.

10.1101/515924 — cell biology — Posted on 2019-01-10

2218 HybridMolDB: a manually curated database dedicated to hybrid molecules for chemical biology and drug discovery

Li, Y.; Zhao, C.; Wei, B.; Wang, L.

10.1101/516765 — bioinformatics — Posted on 2019-01-10

2219 Shoot-to-root translocation of the jasmonate precursor 12-oxo-phytodienoic acid (OPDA) coordinates plant growth responses following tissue damage

Schulze, A.; Zimmer, M.; Mielke, S.; Stellmach, H.; Melnyk, C. W.; Hause, B.; Gasperini, D.

10.1101/517193 — plant biology — Posted on 2019-01-10

2220 Human Phageprints: A high-resolution exploration of oral phages reveals globally-distributed phage families with individual-specific and temporally-stable community compositions

Mahmoudabadi, G.; Homyk, K.; Catching, A.; Foley, H.; Tadmor, A.; Mahmoudabadi, A.; Cheung, A.; Phillips, R.

10.1101/516864 — microbiology — Posted on 2019-01-10

2221 Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain

Jores, J.; Ma, L.; Ssajjakambwe, P.; Schieck, E.; Liljander, A. M.; Chandran, S.; Stoffel, M. H.; Cippa, V. L.; Arfi, Y.; Asad-Garcia, N.; Falquet, L.; Sirand-Pugnet, P.; Blanchard, A.; Lartigue, C.; Posthaus, H.; Labroussaa, F.; Vashee, S.

10.1101/508978 — microbiology — Posted on 2019-01-10

2222 GFP transformation sheds more light on a widespread mycoparasitic interaction

Nemeth, M. Z.; Pintye, A.; Horvath, A. N.; Vagi, P.; Kovacs, G. M.; Gorfer, M.; Kiss, L.

10.1101/516781 — microbiology — Posted on 2019-01-10

2223 Microarray analysis of liver and brain tissues after REM sleep deprivation in rats

Pandey, A.; Kar, S. K.

10.1101/515379 — genomics — Posted on 2019-01-10

2224 A configural model of expert judgement as a preliminary epidemiological study of injury problems: An application to drowning.

Morgan, D.; Ozanne-Smith, J.

10.1101/517300 — epidemiology — Posted on 2019-01-10

2225 Candidate regulators and target genes of drought stress in needles and roots of Norway spruce

Haas, J. C.; Vergara, A.; Hurry, V.; Street, N. R.

10.1101/517151 — plant biology — Posted on 2019-01-10

2226 Binding of Filamentous Actin to CaMKII as a Potential Mechanism for the Regulation of Bidirectional Plasticity by βCaMKII in Cerebellar Purkinje Cells

Pinto, T. M.; Schilstra, M. J.; Roque, A. C.; Steuber, V.

10.1101/517110 — neuroscience — Posted on 2019-01-10

2227 No trace of phase: Corticomotor excitability is not tuned by phase of pericentral mu-rhythm

Madsen, K. H.; Karabanov, A. N.; Krohne, L. G.; Safeldt, M. G.; Tomasevic, L.; Siebner, H. R.

10.1101/513390 — neuroscience — Posted on 2019-01-10

2228 A Multi-Breed Reference Panel and Additional Rare Variation Maximizes Imputation Accuracy in Cattle

Rowan, T. N.; Hoff, J. L.; Crum, T. E.; Taylor, J. F.; Schnabel, R. D.; Decker, J. E.

10.1101/517144 — genomics — Posted on 2019-01-10

Blackburn, A.; Bekheirnia, N.; Uma, V. C.; Rosenfeld, J. A.; Bainbridge, M. N.; Yang, Y.; Liu, P.; Madan-Khetarpal, S.; Delgado, M. R.; Hudgins, L.; Krantz, I.; Rodriguez-Buritica, D.; Wheeler, P. G.; Al Gazali, L.; Al Shamsi, A. M. S. M.; Gomez-Ospina, N.; Chao, H.-T.; Mirzaa, G. M.; Scheuerle, A. E.; Kukolich, M. K.; Scaglia, F.; Eng, C.; Braun, M. C.; Lamb, D. J.; Miller, R. K.; Bekheirnia, M. R.

10.1101/516856 — genetics — Posted on 2019-01-10

2230 A deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure

Trieu, T.; Khurana, E.

10.1101/516849 — bioinformatics — Posted on 2019-01-10

2231 WUSCHEL acts as a rheostat on the auxin pathway to maintain apical stem cells in Arabidopsis

Ma, Y.; Miotk, A.; Sutikovic, Z.; Medzihradszky, A.; Wenzl, C.; Ermakova, O.; Gaillochet, C.; Forner, J.; Utan, G.; Brackmann, K.; Galvan-Ampudia, C. S.; Vernoux, T.; Greb, T.; Lohmann, J. U.

10.1101/468421 — plant biology — Posted on 2019-01-10

2232 A Unified Theory of Early Visual Representations from Retina to Cortex through Anatomically Constrained Deep CNNs

Lindsey, J.; Ocko, S. A.; Ganguli, S.; Deny, S.

10.1101/511535 — neuroscience — Posted on 2019-01-10

2233 Object visibility, not energy expenditure, accounts for spatial biases in human grasp selection

Maiello, G.; Paulun, V. C.; Klein, L. K.; Fleming, R. W.

10.1101/476101 — neuroscience — Posted on 2019-01-10

2234 Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma

Mikulasova, A.; Ashby, C.; Tytarenko, R. G.; Qu, P.; Rosenthal, A.; Dent, J. A.; Ryan, K. R.; Bauer, M. A.; Wardell, C. P.; Hoering, A.; Mavrommatis, K.; Trotter, M.; Deshpande, S.; Tian, E.; Keats, J.; Auclair, D.; Jackson, G. H.; Davies, F. E.; Thakurta, A.; Morgan, G. J.; Walker, B. A.

10.1101/515106 — cancer biology — Posted on 2019-01-10

2235 From the clinic to the bench and back again in one dog year: identifying new treatments for sarcoma using a cross-species personalized medicine pipeline

Rao, S.; Somarelli, J. A.; Altunel, E.; Selmic, L. E.; Byrum, M.; Sheth, M. U.; Cheng, S.; Ware, K. E.; Kim, S. Y.; Prinz, J. A.; Devos, N.; Corcoran, D. L.; Moseley, A.; Soderblom, E.; Hsu, S. D.; Eward, W. C.

10.1101/517086 — cancer biology — Posted on 2019-01-10

2236 Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome

Walker, E. J.; Bettinger, J. Q.; Welle, K. A.; Hryhorenko, J. R.; Ghaemmaghami, S.

10.1101/467290 — biochemistry — Posted on 2019-01-10

2237 Non-invasive characterization of human bone marrow by cell free messenger-RNA reveals response to growth factor stimulation and hematopoietic reconstitution after transplantation

Ibarra, A.; Zhao, Y.; Salathia, N.; Zhuang, J.; Huang, V.; Acosta, A.; Aballi, J.; Toden, S.; Karns, A.; Purnajo, I.; Parks, J.; Guo, L.; Mason, J.; Sigal, D.; Nova, T.; Quake, S.; Nerenberg, M.

10.1101/516666 — molecular biology — Posted on 2019-01-10

2238 Effects of gut microbiota perturbation on Th1- and Th2-biased mice following treatment with Vancomycin

Ray, P.; Aich, P.

10.1101/516898 — microbiology — Posted on 2019-01-10

2239 A genetic system for generating single-sex progeny in mice

Yosef, I.; Shlomovitz, I.; Globus, R.; Edry-Botzer, L.; Munitz, A.; Gerlic, M.; Qimron, U.

10.1101/515064 — developmental biology — Posted on 2019-01-10

2240 NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity

Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M. B.; Stambolic, V.

10.1101/516971 — cancer biology — Posted on 2019-01-10

2241 APC2 is Critical for Ovarian WNT Signalling Control, Fertility and Tumour Suppression

Mohamed, N.-E.; Hay, T.; Reed, K.; Smalley, M.

10.1101/516286 — cancer biology — Posted on 2019-01-10

2242 EK-DRD: a comprehensive database for drug repositioning inspired by experimental knowledge

Zhao, C.; Dai, X.; LI, Y.; Guo, Q.; Zhang, J.; Zhang, X.; Wang, L.

10.1101/515676 — bioinformatics — Posted on 2019-01-10

2243 P53 Transposable Elements and Regulatory Introns Inform Codondex Cell Selection for Autologous Trigger of Immune Cascade

Bermeister, K.

10.1101/508903 — bioinformatics — Posted on 2019-01-10

2244 Accurate peptide fragmentation predictions allow data driven approaches to replace and improve upon proteomics search engine scoring functions

C. Silva, A. S.; Martens, L.; Degroeve, S.

10.1101/428805 — bioinformatics — Posted on 2019-01-10

2245 Extensive splicing across the Saccharomyces genome

Douglass, S.; Leung, C. S.; Johnson, T. L.

10.1101/515163 — molecular biology — Posted on 2019-01-10

2246 Targeting of RBM10 to S1-1 Nuclear Bodies: Targeting Sequences and its Biological Significance

Wang, L.-Y.; Xiao, S.-J.; Kunimoto, H.; Tokunaga, K.; Kojima, H.; Kimura, M.; Yamamoto, T.; Yamamoto, N.; Hong, Z.; Nishio, K.; Yamane, H.; Tani, T.; Nakajima, K.; Iguchi, H.; Inoue, A.

10.1101/516831 — molecular biology — Posted on 2019-01-10

2247 Characterizing variants of unknown significance inrhodopsin: a functional genomics approach

Wan, A.; Place, E.; Pierce, E. A.; Comander, J.

10.1101/512897 — genetics — Posted on 2019-01-10

2248 MroQ is a Novel Abi-domain Protein That Influences Virulence Gene Expression in Staphylococcus aureus via Modulation of Agr Activity

Marroquin, S.; Gimza, B. D.; Tomlinson, B.; Stein, M.; Frey, A.; Keogh, R. A.; Zapf, R. L.; Todd, D. A.; Cech, N. B.; Carroll, R. K.; Shaw, L. N.

10.1101/516914 — microbiology — Posted on 2019-01-10

2249 Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe

Vietri, M.; Schultz, S. W.; Bellanger, A.; Jones, C. M.; Raiborg, C.; Skarpen, E.; Pedurupillay, C. R. J.; Kip, E.; Timmer, R.; Jain, A.; Collas, P.; Knorr, R. L.; Grellscheid, S. N.; Kusumaatmaja, H.; Brech, A.; Micci, F.; Stenmark, H.; Campsteijn, C.

10.1101/517011 — cell biology — Posted on 2019-01-10

2250 Evolutionarily-conserved chromatin crosstalk generates a DOT1L-dose dependency in thymic lymphoma caused by loss of HDAC1

Vlaming, H.; McLean, C.; Korthout, T.; Alemdehy, M. F.; Henriks, S.; Lancini, C.; Palit, S.; Klarenbeek, S.; Molenaar, T. M.; Hoekman, L.; Schmidlin, T. T.; Altelaar, M.; Welsem, T. v.; Dannenberg, J.-H.; Jacobs, H.; van Leeuwen, F.

10.1101/509976 — cell biology — Posted on 2019-01-10

2251 Inferring macro-ecological patterns from local species’ occurrences

Tovo, A.; Formentin, M.; Suweis, S.; Stivanello, S.; Azaele, S.; Maritan, A.

10.1101/387456 — ecology — Posted on 2019-01-10

2252 Introducing RpsA Point Mutation Δ438A or D123A into the Chromosome of M. tuberculosis Confirms its Role in Causing Resistance to Pyrazinamide

Shi, W.; Cui, P.; Niu, H.; Zhang, S.; Tonjum, T.; Zhu, B.; Zhang, Y.

10.1101/505297 — microbiology — Posted on 2019-01-10

2253 Microtubules are necessary for proper Reticulon localization during mitosis

Bergman, Z.; Diaz, U.; Sims, A.; Riggs, B.

10.1101/516773 — cell biology — Posted on 2019-01-10

2254 Microglia motility depends on neuronal activity andpromotes structural plasticity in the hippocampus

Nebeling, F. C.; Poll, S.; Schmid, L. C.; Mittag, M.; Steffen, J.; Keppler, K.; Fuhrmann, M.

10.1101/515759 — neuroscience — Posted on 2019-01-10

2255 Nucleus Accumbens Fast-Spiking Interneurons Constrain Impulsive Action

Pisansky, M. T.; Lefevre, E. M.; Retzlaff, C. L.; Trieu, B. H.; Rothwell, P. E.

10.1101/516609 — neuroscience — Posted on 2019-01-10

2256 E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms

Jolly, M. K.; Ware, K. E.; Xu, S.; Gilja, S.; Shetler, S.; Yang, Y.; Wang, X.; Austin, G.; Runyambo, D.; Hish, A. J.; Bartholf DeWitt, S.; George, J. T.; Kreulen, R. T.; Boss, M.-K.; Lazarides, A. L.; Kerr, D. L.; Gerber, D. G.; Sivaraj, D.; Armstrong, A. J.; Dewhirst, M. W.; Eward, W. C.; Levine, H.; Somarelli, J. A.

10.1101/347815 — cancer biology — Posted on 2019-01-10

2257 A statistical framework for cross-tissue transcriptome-wide association analysis

Hu, Y.; Li, M.; Lu, Q.; Weng, H.; Wang, J.; Zekavat, S. M.; Yu, Z.; Li, B.; Gu, J.; Muchnik, S.; Shi, Y.; Kunkle, B. W.; Mukherjee, S.; Natarajan, P.; Naj, A.; Kuzma, A.; Zhao, Y.; Crane, P. K.; Alzheimer's Disease Genetics Consortium, ; Lu, H.; Zhao, H.

10.1101/286013 — genetics — Posted on 2019-01-10

2258 Obesogenic diet exposure alters uterine natural killer cell biology and impairs vasculature remodeling in mice

Baltayeva, J.; Konwar, C.; Castellana, B.; Mara, D.; Christians, J. K.; Beristain, A. G.

10.1101/275503 — immunology — Posted on 2019-01-09

2259 CANCERSIGN: a user-friendly and robust tool for identification and classification of mutational signatures and patterns in cancer genomes

Bayati, M.; Rabiee, H. R.; Mehrbod, M.; Vafaee, F.; Ebrahimi, D.; Forrest, A.; Alinejad-Rokny, H.

10.1101/424960 — bioinformatics — Posted on 2019-01-09

2260 Evolution of resilience in protein interactomes across the tree of life

Zitnik, M.; Sosic, R.; Feldman, M. W.; Leskovec, J.

10.1101/454033 — systems biology — Posted on 2019-01-09

2261 Non-parametric polygenic risk prediction using partitioned GWAS summary statistics

Chun, S.; Imakaev, M.; Hui, D.; Patsopoulos, N. A.; Neale, B. M.; Kathiresan, S.; Stitziel, N. O.; Sunyaev, S. R.

10.1101/370064 — genetics — Posted on 2019-01-09

2262 Statistical test with sample size and power calculation for paired repeated measures designs of method comparison studies

Bai, Y.; Wang, Z.; Lystig, T. C.; Wu, B.

10.1101/516658 — bioinformatics — Posted on 2019-01-09

2263 Electrophysiological measures of sleep pressure during wakefulness in the course of isolation at the Concordia Antarctica station and physical activity as a countermeasure

Petit, G.; Abeln, V.; Summerer, L.; Schneider, S.; Huber, R.

10.1101/516567 — neuroscience — Posted on 2019-01-09

2264 Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity

Baek, M.; Menon, V.; Jessell, T.; Hantman, A.; Dasen, J.

10.1101/516435 — neuroscience — Posted on 2019-01-09

2265 Murine astrotactins 1 and 2 have similar membrane topology and mature via endoproteolytic cleavage catalyzed by signal peptidase

Lara, P.; Tellgren-Roth, A.; Behesti, H.; Horn, Z.; Schiller, N.; Enquist, K.; Cammenberg, M.; Liljenström, A.; Hatten, M. E.; Von Heijne, G.; Nilsson, I.

10.1101/493858 — neuroscience — Posted on 2019-01-09

2266 Individual-Specific fMRI-Subspaces Improve Functional Connectivity Prediction of Behavior

Kashyap, R.; Kong, R.; Bhattacharjee, S.; Li, J.; Zhou, J.; Yeo, B. T. T.

10.1101/515742 — neuroscience — Posted on 2019-01-09

2267 Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages

Desgrange, A.; Lokmer, J.; Marchiol, C.; Houyel, L.; Meilhac, S.

10.1101/516039 — developmental biology — Posted on 2019-01-09

2268 GToTree: a user-friendly workflow for phylogenomics

Lee, M. D.

10.1101/512491 — bioinformatics — Posted on 2019-01-09

2269 Challenges and opportunities for strain verification by whole-genome sequencing

Gallegos, J.; Adames, N.; Hayrynen, S.; Peccoud, J.

10.1101/515338 — bioinformatics — Posted on 2019-01-09

2270 Bacterioplankton dynamics driven by inter-annual variation in phytoplankton spring bloom communities in the Baltic Sea

Camarena Gomez, M. T.; Ruiz-Gonzalez, C.; Piiparinen, J.; Lipsewers, T.; Sobrino, C.; Logares, R.; Spilling, K.

10.1101/513606 — microbiology — Posted on 2019-01-09

2271 Live cell bioimaging with carbon dots produced in situ by femtosecond laser from intracellular material

Shakhov, A. M.; Astafiev, A. A.; Osychenko, A. A.; Syrchina, M. S.; Nadtochenko, V. A.

10.1101/455808 — biophysics — Posted on 2019-01-09

2272 A practical method for efficient and optimal production of selenomethionine-labeled recombinant protein complexes in the insect cells

Wenzel, S.; Imasaki, T.; Takagi, Y.

10.1101/491548 — biochemistry — Posted on 2019-01-09

2273 Multiple two-photon targeted whole-cell patch-clamp recordings from monosynaptically connected neurons in vivo

Jouhanneau, J.-S.; Poulet, J. F. A.

10.1101/516708 — neuroscience — Posted on 2019-01-09

2274 Evaluation of a potential redox switch in blood coagulation tenase

Cook, K. M.; Butera, D.; Hogg, P. J.

10.1101/515718 — biochemistry — Posted on 2019-01-09

2275 The mir-35 family links maternal germline sex to embryonic viability in C. elegans

Benner, L. K.; Prothro, K. P.; McJunkin, K.

10.1101/516492 — genetics — Posted on 2019-01-09

2276 Cell non-autonomous functions of S100a4 drive fibrotic tendon healing

Ackerman, J.; Studentsova, V.; Best, K.; Knapp, E.; Loiselle, A.

10.1101/516088 — cell biology — Posted on 2019-01-09

2277 Functional systemic CD4 immunity is a differential factor for clinical responses to PD-L1/PD-1 blockade therapy in lung cancer

Zuazo, M.; Arasanz, H.; Fernandez-Hinojal, G.; Garcia-Granda, M. J.; Gato, M.; Bocanegra, A.; Hernandez, B.; Martinez, M.; Teijeira, L.; Morilla, I.; Lecumberri, M. J.; Fernandez de Lascoiti, A.; Vera, R.; Kochan, G.; Escors, D.

10.1101/508739 — cancer biology — Posted on 2019-01-09

2278 Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel

Yin, Y.; Wu, M.; Hsu, A.; Borschel, W.; Borgnia, M.; Lander, G.; Lee, S.-Y.

10.1101/516468 — biochemistry — Posted on 2019-01-09

2279 The population dynamics of a canonical cognitive circuit

Chaudhuri, R.; Gercek, B.; Pandey, B.; Peyrache, A.; Fiete, I.

10.1101/516021 — neuroscience — Posted on 2019-01-09

2280 Cue-reactivity in the ventral striatum characterizes heavy cannabis use, whereas reactivity in the dorsal striatum mediates dependent use

Zhou, X.; Zimmermann, K.; Xin, F.; Derck, R.; Sassmannshausen, A.; Scheele, D.; Hurlemann, R.; Weber, B.; Kendrick, K.; Becker, B.

10.1101/516385 — neuroscience — Posted on 2019-01-09

2281 A simple genetic architecture and low constraint allows rapid floral evolution in a diverse and recently radiating plant genus

Kostyun, J. L.; Gibson, M. J. S.; King, C. M.; Moyle, L. C.

10.1101/516377 — evolutionary biology — Posted on 2019-01-09

2282 A Topological Data Analysis Network Model of Asthma Based on Blood Gene Expression Profiles

Schofield, J. P. R.; Strazzeri, F.; Bigler, J.; Boedigheimer, M.; Adcock, I. M.; Chung, K. F.; Bansal, A.; Knowles, R.; Dahlen, S.-E.; Wheelock, C. E.; Sun, K.; Pandis, I.; Riley, J.; Auffray, C.; De Meulder, B.; Lefaudeux, D.; Ramanan, D.; Sousa, A. R.; Sterk, P. J.; Ewing, R. M.; MacArthur, B. D.; Djukanovic, R.; Sanchez Garcia, R.; Skipp, P. J.

10.1101/516328 — molecular biology — Posted on 2019-01-09

2283 Dissection of complex, fitness-related traits in multiple Drosophila mapping populations offers insight into the genetic control of stress resistance

Everman, E.; McNeil, C.; Hackett, J.; Bain, C.; Macdonald, S. J.

10.1101/383802 — genetics — Posted on 2019-01-09

2284 Fungal Communities in Soybean Cyst Nematode-Infested Soil under Long Term Corn and Soybean Monoculture and Crop Rotation

Strom, N. B.; Hu, W.; Haarith, D.; Chen, S.; Bushley, K.

10.1101/516575 — bioinformatics — Posted on 2019-01-09

2285 Statistical test with sample size and power calculation for paired repeated measures designs of method comparison studies

Bai, Y.; Wang, Z.; Lystig, T. C.; Wu, B.

10.1101/516658 — bioinformatics — Posted on 2019-01-09

2286 The Markov link method: a nonparametric approach to combine observations from multiple experiments

Loper, J.; Bakken, T.; Sumbul, U.; Murphy, G.; Zeng, H.; Blei, D.; Paninski, L.

10.1101/457283 — bioinformatics — Posted on 2019-01-09

2287 Chloroplasts navigate towards the pathogen interface to counteract infection by the Irish potato famine pathogen

Toufexi, A.; Duggan, C.; Pandey, P.; Savage, Z.; Segretin, M. E.; Yuen, L. H.; Gaboriau, D. C. A.; Leary, A. Y.; Khandare, V.; Ward, A. D.; Botchway, S. W.; Bateman, B. C.; Pan, I.; Schattat, M.; Sparkes, I.; Bozkurt, T. O.

10.1101/516443 — plant biology — Posted on 2019-01-09

2288 Exome sequencing of 457 autism families recruited online provides evidence for novel ASD genes

Feliciano, P.; Zhou, X.; Astrovskaya, I.; Turner, T.; Wang, T.; Brueggeman, L.; Barnard, R.; Hsieh, A.; Snyder, L. G.; Muzny, D.; Sabo, A.; The SPARK Consortium, ; Gibbs, R.; Eichler, E.; O'Roak, B.; Michaelson, J.; Volfovsky, N.; Shen, Y.; Chung, W.

10.1101/516625 — genetics — Posted on 2019-01-09

2289 Neuroendocrine negative SCLC is mostly RB1 WT and may be sensitive to CDK4/6 inhibition

Sonkin, D.; Vural, S.; Thomas, A.; Teicher, B. A.

10.1101/516351 — cancer biology — Posted on 2019-01-09

2290 Effects of α-tubulin acetylation on microtubule structure and stability

Eshun-Wilson, L.; Zhang, R.; Portran, D.; Nachury, M.; Toso, D.; Lohr, T.; Vendruscolo, M.; Bonomi, M.; Fraser, J.; Nogales, E.

10.1101/516591 — biophysics — Posted on 2019-01-09

2291 A comparative analysis of cannabis and tobacco smoke exposure on human airway epithelial cell gene expression, immune phenotype, and response to formoterol and budesonide treatment

Aguiar, J. A.; Huff, R. D.; Tse, W.; Stampfli, M. R.; McConkey, B. J.; Doxey, A. C.; Hirota, J.

10.1101/516294 — bioinformatics — Posted on 2019-01-09

2292 Modulation of tonotopic ventral MGB is behaviorally relevant for speech recognition.

Mihai, P. G.; Moerel, M.; de Martino, F.; Trampel, R.; Kiebel, S.; von Kriegstein, K.

10.1101/510164 — neuroscience — Posted on 2019-01-09

2293 Cortical network mechanisms of anodal and cathodal transcranial direct current stimulation in awake primates

Bogaard, A. R.; Lajoie, G.; Boyd, H.; Morse, A.; Zanos, S.; Fetz, E.

10.1101/516260 — neuroscience — Posted on 2019-01-09

2294 Evolution of the embryonic cis-regulatory landscapes between divergent Phallusia and Ciona ascidians.

Madgwick, A.; Magri, M. S.; Dantec, C.; Gailly, D.; Fiuza, U.-M.; Guignard, L.; Hettinger, S.; Gomez-Skarmeta, J. L.; Lemaire, P.

10.1101/371005 — genomics — Posted on 2019-01-09

2295 An X-specific condensin binds to gene regulatory elements and reduces histone modifications associated with active transcription in C. elegans

Street, L. A.; Winterkorn, L. H.; Jiao, C.-Y.; Albritton, S. E.; Sadic, M.; Kramer, M.; Ercan, S.

10.1101/516419 — genomics — Posted on 2019-01-09

2296 Expanding the watch list for potential Ebola virus antibody escape mutations

Patel, J. S.; Quates, C. J.; Johnson, E. L.; Ytreberg, F. M.

10.1101/516161 — biophysics — Posted on 2019-01-09

2297 Representation of auditory motion directions and sound source locations in the human planum temporale

Battal, C.; Rezk, M. A. T.; Mattioni, S.; Vadlamudi, J.; collignon, o.

10.1101/302497 — neuroscience — Posted on 2019-01-09

2298 Robust parallel decision-making in neural circuits with nonlinear inhibition

Kriener, B.; Chaudhuri, R.; Fiete, I. R.

10.1101/231753 — neuroscience — Posted on 2019-01-09

2299 The influence of task outcome on implicit motor learning

Kim, H.; Parvin, D.; Ivry, R.

10.1101/363606 — neuroscience — Posted on 2019-01-09

2300 Description of Klebsiella africanensis sp. nov., Klebsiella variicola subsp. tropicalensis subsp. nov. and Klebsiella variicola subsp. variicola subsp. nov.

Rodrigues, C.; Passet, V.; Rakotondrasoa, A.; Diallo, T. A.; Criscuolo, A.; Brisse, S.

10.1101/516278 — microbiology — Posted on 2019-01-09

2301 Genomic signatures of somatic hybrid vigor due to heterokaryosis in the oomycete pathogen, Bremia lactucae.

Fletcher, K.; Gil, J.; Bertier, L. D.; Kenefick, A.; Wood, K. J.; Zhang, L.; Reyes-Chin-Wo, S.; Cavanaugh, K.; Tsuchida, C.; Wong, J.; Michelmore, R.

10.1101/516526 — genomics — Posted on 2019-01-09

2302 Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern

Lawton, A. K.; Engstrom, T.; Rohrbach, D.; Omura, M.; Turnbull, D. H.; Mamou, J.; Zhang, T.; Schwarz, J. M.; Joyner, A. L.

10.1101/382887 — developmental biology — Posted on 2019-01-09

2303 A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells

Dobrzycki, T.; Krecsmarik, M.; Koyunlar, C.; Rispoli, R.; Peulen-Zink, J.; Gussinklo, K.; de Pater, E.; Patient, R.; Monteiro, R.

10.1101/516203 — developmental biology — Posted on 2019-01-09

2304 Orexin-1 receptor signaling in ventral pallidum regulates demand for the opioid remifentanil

Mohammdkhani, A.; Pantazis, C. B.; Bowrey, H. E.; James, M. H.; Aston-Jones, G.

10.1101/353896 — animal behavior and cognition — Posted on 2019-01-09

2305 A 2.08 A resolution structure of HLB5, a novel cellulase from the anaerobic gut bacterium Parabacteroides johnsonii DSM 18315.

Chang, C.; Brooke, C.; Piao, H.; Mack, J.; Babnigg, G.; Joachimiak, A.; Hess, M.

10.1101/516542 — systems biology — Posted on 2019-01-09

2306 Multi-study inference of regulatory networks for more accurate models of gene regulation

Castro, D. M.; de Veaux, N.; Miraldi, E. R.; Bonneau, R.

10.1101/279224 — systems biology — Posted on 2019-01-09

2307 Plasmids for independently tunable, low-noise expression of two genes

Silva, J. P. N.; Lopes, S. V.; Grilo, D. J.; Hensel, Z.

10.1101/515940 — synthetic biology — Posted on 2019-01-09

2308 Multiplexed temporally focused light shaping through a GRIN lens for precise in-depth optogenetic photostimulation

Accanto, N.; Chen, I.-W.; Ronzitti, E.; Molinier, C.; Tourain, C.; Papagiakoumou, E.; Emiliani, V.

10.1101/515908 — neuroscience — Posted on 2019-01-09

2309 An afferent white matter pathway from the pulvinar to the amygdala facilitates fear recognition

McFadyen, J.; Mattingley, J. B.; Garrido, M. I.

10.1101/277368 — neuroscience — Posted on 2019-01-09

2310 Gene-expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ

Foley, J. W.; Zhu, C.; Jolivet, P.; Zhu, S. X.; Lu, P.; Meaney, M. J.; West, R. B.

10.1101/207340 — genomics — Posted on 2019-01-09

2311 Copy number aberrations drive kinase re-wiring leading to genetic vulnerabilities in cancer

Memon, D.; Gill, M. G.; Papachristou, E.; Ochoa, D.; D'Santos, C.; Miller, M. L.; Beltrao, P.

10.1101/515932 — genomics — Posted on 2019-01-09

2312 Long-read sequencing identifies GGC repeat expansion in human-specific NOTCH2NLC associated with neuronal intranuclear inclusion disease

Sone, J.; Mitsuhashi, S.; Fujita, A.; Mizuguchi, T.; Mori, K.; Koike, H.; Hashiguchi, A.; Takashima, H.; Sugiyama, H.; Kohno, Y.; Takiyama, Y.; Maeda, K.; Doi, H.; Koyano, S.; Takeuchi, H.; Kawamoto, M.; Kohara, N.; Ando, T.; Ieda, T.; Kita, Y.; Kokubun, N.; Tsuboi, Y.; Katsuno, M.; Iwasaki, Y.; Yoshida, M.; Tanaka, F.; Suzuki, I. K.; Frith, M. C.; Matsumoto, N.; Sobue, G.

10.1101/515635 — genetics — Posted on 2019-01-09

2313 Character displacement within the breeding area questions reinforcement in Ficedula flycatchers

Grinkov, V. G.; Palko, I. V.; Sternberg, H.

10.1101/515916 — evolutionary biology — Posted on 2019-01-09

2314 The origin of the central dogma through conflicting multi-level selection

Takeuchi, N.; Kaneko, K.

10.1101/515767 — evolutionary biology — Posted on 2019-01-09

2315 A keeper of many crypts: the parasitoid Euderus set manipulates the behavior of a taxonomically diverse array of oak gall wasp species

Ward, A. K. G.; Khodor, O. S.; Egan, S. P.; Weinersmith, K. L.; Forbes, A. A.

10.1101/516104 — ecology — Posted on 2019-01-09

2316 The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A)-translation

10.1101/516005 — molecular biology — Posted on 2019-01-09

2317 Immune gene expression profiling reveals heterogeneity in luminal breast tumors

Zhu, B.; Tse, S. L. A.; Wang, D.; Koka, H.; Zhang, T.; Abubakar, M.; Lee, P.; Wang, F.; Wu, C.; Tsang, K. H.; Chan, W.-c.; Law, S. H.; Li, M.; Li, W.; Wu, S.; Liu, Z.; Huang, B.; Zhang, H.; Tang, E.; Kan, Z.; Lee, S.; Park, Y. H.; Nam, S. J.; Wang, M.; Sun, X.; Jones, K.; Zhu, B.; Hutchinson, A.; Hicks, B.; Prokunina-Olsson, L.; Shi, J.; Garcia-Closas, M.; Chanock, S.; Yang, X. R.

10.1101/515486 — genomics — Posted on 2019-01-09

2318 Association of variants within the GST and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysis

Richardson, M.; Kirkham, J.; Dwan, K.; Sloan, D. J.; Davies, G.; Jorgensen, A. L.

10.1101/515817 — genetics — Posted on 2019-01-09

2319 A stress response that allows highly mutated eukaryotic cells to survive and proliferate

Zabinsky, R. A.; Mares, J.; She, R.; Zeman, M. K.; Silvers, T. R.; Jarosz, D. F.

10.1101/515460 — genetics — Posted on 2019-01-09

2320 Vitamin D: marker, cause or consequence of depression? An exploration using genomics

Milaneschi, Y.; Peyrot, W. J.; Nivard, M. G.; Mbarek, H.; Boomsma, D. I.; Penninx, B. W.

10.1101/516013 — genomics — Posted on 2019-01-09

2321 Antibiotic collateral sensitivity is contingent on the repeatability of evolution

Nichol, D.; Rutter, J.; Bryant, C.; Hujer, A. M.; Lek, S.; Adams, M. D.; Jeavons, P.; Anderson, A.; Bonomo, R.; Scott, J.

10.1101/185892 — evolutionary biology — Posted on 2019-01-09

2322 Medial prefrontal cortex population activity is plastic irrespective of learning

Singh, A.; Peyrache, A.; Humphries, M. D.

10.1101/027102 — neuroscience — Posted on 2019-01-09

2323 Reduced Default Mode Network Functional Connectivity in Recurrent Patients with Major Depressive Disorder: Evidence from 25 Cohorts

Yan, C.-G.; Chen, X.; Li, L.; Castellanos, F. X.; Bai, T.-J.; Bo, Q.-J.; Chen, G.-M.; Chen, N.-X.; Chen, W.; Cheng, C.; Cheng, Y.-Q.; Cui, X.-L.; Duan, J.; Fang, Y.-R.; Gong, Q.-Y.; Guo, W.-B.; Hou, Z.-H.; Hu, L.; Kuang, L.; Li, F.; Li, K.-M.; Li, T.; Liu, Y.-S.; Liu, Z.-N.; Long, Y.-C.; Luo, Q.-H.; Meng, H.-Q.; Peng, D.-H.; Qiu, H.-T.; Qiu, J.; Shen, Y.-D.; Shi, Y.-S.; Si, T.-M.; Wang, C.-Y.; Wang, F.; Wang, K.; Wang, L.; Wang, X.; Wang, Y.; Wu, X.-P.; Wu, X.-R.; Xie, C.-M.; Xie, G.-R.; Xie, H.-Y.; Xie, P.; Xu, X.-F.; Yang, H.; Yang, J.; Yao, J.-S.; Yao, S.-Q.; Yin, Y.-Y.; Yuan, Y.-G.; Zhang,

10.1101/321745 — neuroscience — Posted on 2019-01-09

2324 Multivoxel Pattern Analysis Reveals Dissociations Between Subjective Fear and Its Physiological Correlates

Taschereau-Dumouchel, V.; Kawato, M.; Lau, H.

10.1101/515973 — neuroscience — Posted on 2019-01-09

2325 Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor

Suh, Y. H.; Lee, S.; Park, S.; Lee, H.; Han, S.; Song, J.-m.; Han, D.

10.1101/515999 — neuroscience — Posted on 2019-01-09

2326 Parkinsons disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input

Baaske, M. K.; Kormann, E.; Holt, A. B.; Gulberti, A.; McNamara, C. G.; Poetter-Nerger, M.; Westphal, M.; Engel, A. K.; Hamel, W.; Brown, P.; Moll, C. K. E.; Sharott, A.

10.1101/513234 — neuroscience — Posted on 2019-01-09

2327 Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Kolitsida, P.; Zhou, J.; Rackiewicz, M.; Dengjel, J.; Abeliovich, H.

10.1101/513135 — cell biology — Posted on 2019-01-09

2328 egKnock: identifying direct gene knockout strategies for microbial strain optimization based on metabolic network with gene-protein-reaction relationships

Xu, Z.

10.1101/514653 — synthetic biology — Posted on 2019-01-09

2329 Genomic data provides new insights on the demographic history and the extent of recent material transfers in Norway spruce

Chen, J.; li, l.; Milesi, P.; Jansson, G.; Berlin, M.; Karlsson, B.; Aleksic, J.; Vendramin, G. G.; Lascoux, M.

10.1101/402016 — evolutionary biology — Posted on 2019-01-09

2330 Planar differential growth rates determine the position of folds in complex epithelia

Tozluoglu, M.; Duda, M.; Kirkland, N. J.; Barrientos, R.; Burden, J. J.; Munoz, J. J.; Mao, Y.

10.1101/515528 — biophysics — Posted on 2019-01-09

2331 StormGraph: An automated graph-based algorithm for quantitative clustering analysis of single-molecule localization microscopy data

Scurll, J.; Abraham, L.; Zheng, D. W.; Tafteh, R.; Chou, K.; Gold, M. R.; Coombs, D.

10.1101/515627 — biophysics — Posted on 2019-01-09

2332 Interactions between dosage compensation complex components Msl-1, Msl-2 and NURF component NURF301 with long non-coding RNA gene hsrω

Chaturvedi, D. P.

10.1101/515726 — genetics — Posted on 2019-01-09

2333 Competing interactions modulate the activity of Sgs1 during DNA end resection

Kasaciunaite, K.; Fettes, F.; Levikova, M.; Daldrop, P.; Cejka, P.; Seidel, R.

10.1101/515791 — biochemistry — Posted on 2019-01-09

2334 Precursors to Chunking Vanish When Working Memory Capacity is exceeded

Tarnow, E.; Ershova, R.

10.1101/515601 — neuroscience — Posted on 2019-01-09

2335 Epithelial invagination by vertical telescoping

Li, J.; Economou, A. D.; Green, J. B. A.

10.1101/515981 — developmental biology — Posted on 2019-01-09

2336 Aurora B-INCENP localization at centromeres/inner kinetochores is essential for chromosome bi-orientation in budding yeast

Garcia-Rodriguez, L. J.; Kasciukovic, T.; Denninger, V.; Tanaka, T. U.

10.1101/515924 — cell biology — Posted on 2019-01-09

2337 Transient Probability Distributions of Gene Regulatory Networks with Slow Promoter Kinetics

Ali Al-Radhawi, M.

10.1101/514547 — systems biology — Posted on 2019-01-09

2338 Modeling Primary Fields of TMS Coils with the Fast Multipole Method

Makarov, S. N.; Navarro de Lara, L.; Noetscher, G. M.; Nummenmaa, A.

10.1101/514919 — neuroscience — Posted on 2019-01-09

2339 The influence of image masking on object representations during rapid serial visual presentation

Robinson, A. K.; Grootswagers, T.; Carlson, T. A.

10.1101/515619 — neuroscience — Posted on 2019-01-09

2340 Connectivity of variants in eQTL networks dictates reproducibility and functionality

Gaynor, S.; Fagny, M.; Lin, X.; Platig, J.; Quackenbush, J.

10.1101/515551 — systems biology — Posted on 2019-01-09

2341 Membrane potential resonance arising from responses of neuronal models to oscillatory inputs in current versus voltage clamp

Rotstein, H. G.; Nadim, F.

10.1101/515510 — neuroscience — Posted on 2019-01-09

2342 Transcriptomics supports local sensory regulation in the antennae of the kissing bug Rhodnius prolixus

Latorre Estivalis, J. M.; Sterkel, M.; Ons, S.; Lorenzo, M. G.

10.1101/515353 — neuroscience — Posted on 2019-01-09

2343 Activity of a long-acting injectable bedaquiline formulation in a paucibacillary mouse model of latent tuberculosis infection

Kaushik, A.; Ammerman, N. C.; TYAGI, S.; Saini, V.; Vervoort, I.; Lachau-Durand, S.; Nuermberger, E.; Andries, K.

10.1101/515692 — microbiology — Posted on 2019-01-09

2344 Community size affects the signals of selection and ecological drift on biodiversity

Siqueira, T.; Saito, V. S.; Bini, L. M.; Melo, A. S.; Petsch, D. K.; Landeiro, V. L.; Tolonen, K. T.; Jyrkankallio-Mikkola, J.; Soininen, J.; Heino, J.

10.1101/515098 — ecology — Posted on 2019-01-09

2345 Partial ligand-receptor engagement yields functional bias at the human complement receptor, C5aR1

Pandey, S.; Li, X.; Srivastava, A.; Baidya, M.; Kumari, P.; Dwivedi, H.; Ghosh, E.; Woodruff, T.; Shukla, A. K.

10.1101/515700 — biochemistry — Posted on 2019-01-09

2346 Reversible silencing of endogenous receptors in intact brain tissue using two-photon pharmacology

Pittolo, S.; Lee, H.; Lladoo, A.; Tosi, S.; Bosch, M.; Bardia, L.; Gomez-Santacana, X.; Llebaria, A.; Soriano, E.; Colombelli, J.; Poskanzer, K. E.; Perea, G.; Gorostiza, P.

10.1101/515288 — pharmacology and toxicology — Posted on 2019-01-09

2347 Sensitivity of single units in the LSO of decerebrate cat to sinusoidally amplitude modulated tones

Greene, N. T.; Davis, K. A.

10.1101/515270 — neuroscience — Posted on 2019-01-09

2348 Lower-limb rigidity is associated with frequent falls in Parkinson disease

McKay, J. L.; Hackney, M. E.; Factor, S. A.; Ting, L. H.

10.1101/515155 — neuroscience — Posted on 2019-01-09

2349 Effects of enucleation on the direct reciprocal corticocortical connections between primary visual and somatosensory cortices of the mouse

Masse, I.; Bronchti, G.; Boire, D.

10.1101/515262 — neuroscience — Posted on 2019-01-09

2350 The role of hippocampal spatial representations in contextualization and generalization of fear

de Voogd, L. D.; Murray, Y. P. J.; Barte, R. M.; van der Heide, A.; Fernandez, G.; Doeller, C. F.; Hermans, E. J.

10.1101/514505 — neuroscience — Posted on 2019-01-09

2351 Direct medical and non-medical costs of a one-year care pathway for early breast cancer: results of a French multicenter prospective study

Hequet, D.; huchon, c.; Soilly, A.-L.; asselain, b.; berseneff, h.; trichot, c.; Combes, A.; alves, k.; nguyen, T.; rouzier, r.; baffert, s.

10.1101/514182 — epidemiology — Posted on 2019-01-09

2352 Anterior Cleft Palate due to Cbfb deficiency and its rescue by folic acid

Yamashiro, T.

10.1101/515650 — developmental biology — Posted on 2019-01-09

2353 Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining

Barupal, D. K.; Gao, B.; Budczies, J.; Phinney, B.; Perroud, B.; Denkert, C.; Fiehn, O.

10.1101/515403 — bioinformatics — Posted on 2019-01-09

2354 Perception of naturally dead conspecifics impairs health and longevity through serotonin signaling in Drosophila

Chakraborty, T. S.; Gendron, C. M.; Lyu, Y.; Munneke, A. S.; DeMarco, M. N.; Hoisington, Z. W.; Pletcher, S. D.

10.1101/515312 — animal behavior and cognition — Posted on 2019-01-09

2355 Sexual selection and the evolution of male and female cognition: a test using experimental evolution in seed beetles

Baur, J.; d'Amour, J.; Berger, D.

10.1101/514711 — animal behavior and cognition — Posted on 2019-01-09

2356 From Habitat Use to Social Behavior: Natural History of a Voiceless Poison Frog, Dendrobates tinctorius

Rojas, B.; Pasukonis, A.

10.1101/515122 — animal behavior and cognition — Posted on 2019-01-09

2357 Mice carrying a humanized Foxp2 knock-in allele show region-specific shifts of striatal Foxp2 expression levels

Schreiweis, C.; Irinopoulou, T.; Vieth, B.; Laddada, L.; Oury, F.; Burguiere, E.; Enard, W.; Groszer, M.

10.1101/514893 — neuroscience — Posted on 2019-01-09

2358 Allele-Specific Expression and High-Throughput Reporter Assay Reveal Functional Variants in Human Brains with Alcohol Use Disorders

Rao, X.; Thapa, K. S.; Chen, A. B.; Lin, H.; Gao, H.; Reiter, J. L.; Hargreaves, K. A.; Ipe, J.; Lai, D.; Xuei, X.; Gu, H.; Kapoor, M.; Farris, S. P.; Tischfield, J.; Foroud, T.; Goate, A. M.; Skaar, T. C.; Mayfield, R. D.; Edenberg, H. J.; Liu, Y.

10.1101/514992 — neuroscience — Posted on 2019-01-09

2359 The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures

Girard, B.; Tuduri, P.; Moreno, M. P.; Sakkaki, S.; Barboux, C.; Bouschet, T.; Varrault, A.; Vitre, J.; McCort, I.; Dairou, J.; Acher, F.; Fagni, L.; Marchi, N.; Perroy, J.; Bertaso, F.

10.1101/514844 — neuroscience — Posted on 2019-01-09

2360 Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 but is unnecessary during S phase for establishing cohesion

Nasmyth, K. A.; Srinivasan, M.; Petela, N. J.; Scheinost, J. C.; Collier, J.; Voulgaris, M.; Brunet-Roig, M.; Beckouët, F.; Hu, B.

10.1101/513960 — molecular biology — Posted on 2019-01-09

2361 Mycobacterium tuberculosis hijacks an evolutionary recent IFN-IL-6-CEBP axis linked to monocyte development and disease severity in humans

Delgobo, M.; Kozlova, E.; Rocha, E. L.; Rodrigues-Luis, G. F.; Mendes, D. A.; Mascarin, L.; Dias, G.; Patricio, D. O.; Dierckx, T.; Bicca, M. A.; Breton, G.; Rovaris, D.; Moral, J. D.; Mansur, D. S.; Weyenbergh, J. V.; Bafica, A.

10.1101/514943 — immunology — Posted on 2019-01-09

2362 Visual signal evolution along complementary color axes in four bird lineages

Krishnan, A.; Singh, A.; Tamma, K.

10.1101/514778 — ecology — Posted on 2019-01-09

2363 Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

Shao, D.; Cheng, S.; Guo, F.; Yuan, Y.; Hu, K.; Wang, Z.; Meng, X.; Jin, X.; Xiong, Y.; Chai, X.; Li, H.; Zhang, Y.; Zhang, H.; Liu, J.; Ye, M.

10.1101/514539 — cancer biology — Posted on 2019-01-09

2364 RegSNPs-Intron: A Computational Framework For Prioritizing Intronic Single Nucleotide Variants in Human Genetic Disease

Lin, H.; Hargreaves, K. A.; Li, R.; Reiter, J. L.; Mort, M.; Cooper, D. N.; Zhou, Y.; Eadon, M. T.; Dolan, M. E.; Ipe, J.; Skaar, T.; Liu, Y.

10.1101/515171 — bioinformatics — Posted on 2019-01-09

2365 System analysis of the functional cross-talk between PPAR , LXR and FXR in the human HepaRG liver cells

Wigger, L.; Casals Casas, C.; Baruchet, M.; Trang, K. B.; Pradervand, S.; Naldi, A.; Desvergne, B.

10.1101/514976 — physiology — Posted on 2019-01-09

2366 Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer’s Disease

Hsieh, Y.-C.; Guo, C.; Yalamanchili, H. K.; Abreha, M.; Al-Ouran, R.; Li, Y.; Dammer, E. B.; Lah, J. J.; Levey, A. I.; Bennett, D. A.; De Jager, P. L.; Seyfried, N. T.; Liu, Z.; Shulman, J. M.

10.1101/514927 — neuroscience — Posted on 2019-01-09

2367 Optical clearing of living brains with MAGICAL to extend in vivo imaging

Iijima, K.; Oshima, T.; Kawakami, R.; Nemoto, T.

10.1101/507426 — neuroscience — Posted on 2019-01-09

2368 Cortisol associated with hypometabolism across the Alzheimer’s disease spectrum

Wirth, M.; Huijbers, W.; Lange, C.

10.1101/514968 — neuroscience — Posted on 2019-01-09

2369 Paracoccin overexpression in Paracoccidioides brasiliensis reveals the influence of chitin hydrolysis on fungal virulence and host immune response

Goncales, R. A.; Vieira, V. C. S.; Ricci-Azevedo, R.; Fernandes, F. F.; Thomaz, S. M. d. O.; Carvalho, A.; Vendruscolo, P. E.; Cunha, C.; Roque-Barreira, M. C.; Rodrigues, F.

10.1101/515056 — microbiology — Posted on 2019-01-09

2370 Diversity and function of fungi associated with the fungivorous millipede, Brachycybe lecontii

Macias, A. M.; Marek, P. E.; Morrissey, E. M.; Brewer, M. S.; Short, D. P. G.; Stauder, C. M.; Wickert, K. L.; Berger, M. C.; Metheny, A. M.; Stajich, J. E.; Boyce, G.; Rio, R. V. M.; Panaccione, D. G.; Wong, V.; Jones, T. H.; Kasson, M. T.

10.1101/515304 — microbiology — Posted on 2019-01-09

2371 Microarray analyses of liver and brain tissues after REM sleep deprivation in rats

Pandey, A.; Kar, S. K.

10.1101/515379 — genomics — Posted on 2019-01-09

2372 A neuroprosthetic system to restore neuronal communication in modular networks

Buccelli, S.; Bornat, Y.; Colombi, I.; Ambroise, M.; Martines, L.; Pasquale, V.; Bisio, M.; Tessadori, J.; Nowak, P.; Grassia, F.; Averna, A.; Tedesco, M.; Bonifazi, P.; Difato, F.; Massobrio, P.; Levi, T.; Chiappalone, M.

10.1101/514836 — bioengineering — Posted on 2019-01-09

2373 Calcitriol and Non-Calcemic Vitamin D Analogue, 22 Oxacalcitriol, Attenuate Developmental and Pathological Ocular Angiogenesis Ex Vivo and In Vivo

Merrigan, S.; Park, B.; Ali, Z.; Jensen, L.; Corson, T.; Kennedy, B.

10.1101/515387 — pharmacology and toxicology — Posted on 2019-01-09

2374 Dual-site high-density 4Hz transcranial alternating current stimulation applied over auditory and motor cortical speech areas does not influence auditory-motor mapping

Preisig, B. C.; Sjerps, M. J.; Kosem, A.; Riecke, L.

10.1101/514687 — neuroscience — Posted on 2019-01-09

2375 Sensorimotor functional connectivity in unilateral cerebral palsy: influence of corticospinal tract wiring pattern and clinical correlates

Simon-Martinez, C.; Jaspers, E.; Alaerts, K.; Ortibus, E.; Balsters, J.; Mailleux, L.; Blommaert, J.; Sleurs, C.; Klingels, K.; Amant, F.; Uyttebroeck, A.; Wenderoth, N.; Feys, H.

10.1101/515866 — neuroscience — Posted on 2019-01-09

2376 Dynamic coding of choice targets in the perirhinal cortex

Ohnuki, T.; Osako, Y.; Manabe, H.; Sakurai, Y.; Hirokawa, J.

10.1101/514612 — neuroscience — Posted on 2019-01-09

2377 Attention hinges on tuned normalization strength within human visual cortex

Bloem, I. M.; Ling, S.

10.1101/515254 — neuroscience — Posted on 2019-01-09

2378 Visual Entrainment at 10 Hz causes periodic modulation of the Flash Lag Illusion

Chota, S.; VanRullen, R.

10.1101/515114 — neuroscience — Posted on 2019-01-09

2379 False-positive neuroimaging: Undisclosed flexibility in testing spatial hypotheses allows presenting anything as a replicated finding

Hong, Y.; Yoo, Y.; Wager, T.; Woo, C.-W.

10.1101/514521 — neuroscience — Posted on 2019-01-09

2380 Nonobese subjects of Bacteroides and Prevotella enterotypes responded differentially to calorie restriction intervention

Zou, H.; Wang, D.; Ren, H.; Fang, C.; Shi, Z.; Zhang, P.; Chen, P.; Wang, J.; Yang, H.; Cai, K.; Zhong, H.

10.1101/514596 — microbiology — Posted on 2019-01-09

2381 Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates

Bravo Ruiz, G.; Ross, Z. K.; Schelenz, S.; Gow, N. A. R.; Lorenz, A.

10.1101/514745 — microbiology — Posted on 2019-01-09

2382 The Toxoplasma Vacuolar H+-ATPase regulates intracellular pH, and impacts the maturation of essential secretory proteins

Stasic, A. J.; Chasen, N. M.; Dykes, E. J.; Vella, S. A.; Asady, B.; Starai, V. J.; Moreno, S.

10.1101/515296 — microbiology — Posted on 2019-01-09

2383 Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome

Talkish, J.; Igel, H.; Perriman, R. J.; Shiue, L.; Katzman, S.; Munding, E. M.; Shelansky, R.; Donohue, J. P.; Ares, M.

10.1101/515197 — genomics — Posted on 2019-01-09

2384 It takes extremes to be robust

Bastos Rocha, F.; Dulcetti Vibranovski, M.; Klaczko, L. B.

10.1101/478784 — evolutionary biology — Posted on 2019-01-09

2385 Microbial associations and spatial proximity predict North American moose (Alces alces) gastrointestinal community composition

Fountain-Jones, N. M.; Clark, N.; Kinsley, A.; Carstensen, M.; Forrester, J.; Johnson, T. J.; Miller, E.; Moore, S.; Wolf, T.; Craft, M.

10.1101/514604 — ecology — Posted on 2019-01-09

2386 Diverse stepping motions of cytoplasmic dynein revealed by kinetic modeling

Kubo, S.; Shima, T.; Takada, S.

10.1101/516179 — biophysics — Posted on 2019-01-09

2387 CellSIUS provides sensitive and specific detection of rare cell populations from complex single cell RNA-seq data

Wegmann, R.; Neri, M.; Schuierer, S.; Bilican, B.; Hartkopf, H.; Nigsch, F.; Mapa, F.; Waldt, A.; Cuttat, R.; Salick, M. R.; Raymond, J.; Kaykas, A.; Roma, G.; Gubser Keller, C.

10.1101/514950 — bioinformatics — Posted on 2019-01-09

2388 Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode Caenorhabditis remanei

O'Connor, C. H.; Sikkink, K. L.; Nelson, T. C.; Fierst, J.; Cresko, W. A.; Phillips, P. C.

10.1101/515320 — evolutionary biology — Posted on 2019-01-09

2389 EvolvingSTEM: A microbial evolution-in-action curriculum that enhances learning of evolutionary biology and increases interest in STEM

Cooper, V. S.; Warren, T. M.; Matela, A. M.; Handwork, M.; Scarponi, S.

10.1101/514513 — evolutionary biology — Posted on 2019-01-09

2390 Castration-resistant prostate cancer: Androgen receptor inactivation induces telomere DNA damage, and damage response inhibition leads to cell death

Reddy, V.; Iskander, A.; Hwang, C.; Divine, G.; Menon, M.; Barrack, E. R.; Reddy, G. P.-v.; Kim, S.-H.

10.1101/516138 — cancer biology — Posted on 2019-01-09

2391 Ion counting demonstrates a high electrostatic potential of the nucleosome

Gebala, M.; Johnson, S.; Narlikar, G.; Herschlag, D.

10.1101/514471 — biophysics — Posted on 2019-01-09

2392 An incremental training method with automated, extendible T-maze for training spatial behavioral tasks in rodents

Holleman, E.; Maka, J.; Schroeder, T.; Battaglia, F.

10.1101/514703 — animal behavior and cognition — Posted on 2019-01-09

2393 Urinary proteome of dogs with kidney injury during babesiosis

Winiarczyk, D.; Michalak, K.; Adaszek, L.; Winiarczyk, M.; Madany, J.; Winiarczyk, S.

10.1101/516120 — pathology — Posted on 2019-01-09

2394 Afferent connections of the primary somatosensory cortex of the mouse for contextual and multisensory processing

Masse, I. O.; Blanchet-Godbout, S.; Bronchti, G.; Boire, D.

10.1101/514414 — neuroscience — Posted on 2019-01-09

2395 Integrative methylome and transcriptome analysis of Japanese flounder (Paralichthys olivaceus) skeletal muscle during development

he, f.; Zhang, J.; Wu, S.; Huang, Y.; Wen, H.; Zhang, M.; Li, J.; Li, Y.; Qi, X.

10.1101/516187 — epidemiology — Posted on 2019-01-09

2396 Spatial distribution of breast cancer in Sudan 2010-2016

Elbasheer, M. M. A.; Alkhidir, A. G. A.; Mohammed, S. M. A.; Abbas, A. A. H.; Mohamed, A. O.; Bereir, I. M.; Abdalazeez, H. R.; Noma, M.

10.1101/516062 — epidemiology — Posted on 2019-01-09

2397 A simple and effective sampler to collect undisturbed cores from tidal marshes

Giannopoulos, G.; Lee, D. Y.; Neubauer, S. C.; Brown, B. L.; Franklin, R.

10.1101/515825 — ecology — Posted on 2019-01-09

2398 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule

Li, W.; Ward, F. R.; McClure, K.; Chang, S. T.; Montabana, E.; Liras, S.; Dullea, R.; Cate, J.

10.1101/315325 — biophysics — Posted on 2019-01-09

2399 Validating indicators of CNS disorders in a swine model of neurological disease

Swier, V. J.; White, K.; Meyerholz, D. K.; Chefdeville, A.; Khanna, R.; Sieren, J. C.; Quelle, D. E.; Weimer, J. M.

10.1101/514398 — neuroscience — Posted on 2019-01-09

2400 Meta-analysis identifies microbial signatures of disease in murine models of inflammatory bowel disease

Saha, S.; Martin, A.; Navarre, W.

10.1101/515205 — microbiology — Posted on 2019-01-09

2401 Modulation and recruitment of TRF2 at viral telomeres during human herpesvirus 6A/B infection

Gilbert-Girard, S.; Gravel, A.; Collin, V.; Wight, D. J.; Kaufer, B. B.; Lazzerini, E.; Flamand, L.

10.1101/514075 — microbiology — Posted on 2019-01-09

2402 Genomic analysis of natural intra-specific hybrids among Ethiopian isolates of Leishmania donovani

Cotton, J.; Durrant, C.; Franssen, S.; Gelanew, T.; Hailu, A.; Mateus, D.; Sanders, M.; Berriman, M.; Volf, P.; Miles, M.; Yeo, M.

10.1101/516211 — genomics — Posted on 2019-01-09

2403 MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

Cairns, J.; Ingle, J.; Kalari, K.; Shepherd, L. E.; Kubo, M.; Goetz, M. P.; Weinshilboum, R. M.; Wang, L.

10.1101/513879 — cancer biology — Posted on 2019-01-09

2404 Expanding the watch list for potential Ebola virus antibody escape mutations

Patel, J. S.; Quates, C. J.; Johnson, E. L.; Ytreberg, F. M.

10.1101/516161 — biophysics — Posted on 2019-01-09

2405 NanoR: An user-friendly R package to analyze and compare nanopore sequencing data

Bolognini, D.; Bartalucci, N.; Mingrino, A.; Vannucchi, A. M.; Magi, A.

10.1101/514232 — bioinformatics — Posted on 2019-01-09

2406 Polymerase recycling contributes to transcriptional noise

Cavallaro, M.; Walsh, M. D.; Jones, M.; Teahan, J.; Tiberi, S.; Finkenstadt, B.; Hebenstreit, D.

10.1101/514174 — systems biology — Posted on 2019-01-09

2407 Depression and Anxiety in Healthcare Staffs in A Tertiary University Hospital in Luoyang, Henan Province: A Cross-Sectional Observational Study

Wang, H.; Qing, X.; Li, L.; Zhang, L.; Ruan, J.; Niu, X.; Liu, X.; Wu, R.; Li, J.; Fan, K.; Chang, X.; Zhang, M.; Li, L.; Zhang, Z.; Zhang, S.

10.1101/516153 — scientific communication and education — Posted on 2019-01-09

2408 Systematic analysis of dark and camouflaged genes: disease-relevant genes hiding in plain sight

Ebbert, M. T. W.; Jensen, T. D.; Jansen-West, K.; Sens, J. P.; Reddy, J. S.; Ridge, P. G.; Kauwe, J. S. K.; Belzil, V.; Pregent, L.; Carrasquillo, M. M.; Keene, D.; Larson, E.; Crane, P.; Asmann, Y.; Ertekin-Taner, N.; Younkin, S. G.; Ross, O. A.; Rademakers, R.; Petrucelli, L.; Fryer, J. D.

10.1101/514497 — genomics — Posted on 2019-01-09

2409 Dietary Vitamin A intakes among Pregnant Women Attending Antenatal Care in Health Facilities: As a connotation for the progress of vitamin A Deficiency in Dessie Town, North East Ethiopia

Koricho, Z.; Mekonnen, T. C.; Attomssa, G. E.; Tadesse, S. E.

10.1101/516047 — epidemiology — Posted on 2019-01-09

2410 Persistence of traditional and emergence of new structural drivers and factors for the HIV epidemic in rural Uganda; a qualitative study

Bajunirwe, F.; Akakimpa, D.; Tumwebaze, F. P.; Abongomera, G.; Mugyenyi, P. N.; Kityo, C. M.

10.1101/516054 — epidemiology — Posted on 2019-01-09

2411 Understanding variation in maternal health service coverage and maternal health outcomes among districts in Rwanda

Bijlmakers, L.; Sayinzoga, F.; Tetui, M.; van der Velden, K.; van Dillen, J.

10.1101/516112 — epidemiology — Posted on 2019-01-09

2412 Absenteeism and indirect costs during the year following the diagnosis of an operable breast cancer

Ferrier, C.; Thebaut, C.; Levy, P.; Baffert, S.; asselain, b.; Rouzier, R.; Hequet, D.

10.1101/514190 — epidemiology — Posted on 2019-01-09

2413 Sarcopenia is an independent predictor of hospitalization in chronic kidney disease outpatients

Jeong, H. Y.; Ahn, W.; Kim, J. C.; Choi, Y. B.; Kim, J.; Jun, H. H.; Lee, S.; Yang, D. H.; Oh, J.; Bae, J.; Lee, S.-Y.

10.1101/516096 — scientific communication and education — Posted on 2019-01-09

2414 Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity

Pfefferle, A.; Jacobs, B.; Ask, E. H.; Lorenz, S.; Clancy, T.; Goodridge, J. P.; Sohlberg, E.; Malmberg, K.-J.

10.1101/514463 — immunology — Posted on 2019-01-09

2415 Comprehensive biodiversity analysis via ultra-deep patterned flow cell technology: a case study of eDNA metabarcoding seawater

Singer, G.; Fahner, N. A.; Barnes, J.; McCarthy, A.; Hajibabaei, M.

10.1101/515890 — genomics — Posted on 2019-01-09

2416 Identification of seed coat pattern trait QTL and a description of seed coat development in cowpea (Vigna unguiculata Walp.)

Herniter, I. A.; Lo, R.; Munoz-Amatrain, M.; Lo, S.; Guo, Y.-N.; Huynh, B.-L.; Lucas, M.; Jia, Z.; Roberts, P. A.; Close, T. J.

10.1101/514455 — genetics — Posted on 2019-01-09

2417 Performance in a novel environment subject to ghost competition.

Bisschop, K.; Mortier, F.; Bonte, D.; Etienne, R.

10.1101/515833 — evolutionary biology — Posted on 2019-01-09

2418 Missense variants in health and disease target distinct functional pathways and proteomics features

Laddach, A.; Ng, J. C.-F.; Fraternali, F.

10.1101/512764 — bioinformatics — Posted on 2019-01-09

2419 Response relationships between CO2, CH4 and N2O emissions and microbial functional groups in wetland sediments after trace metal addition.

Giannopoulos, G.; Hartop, K. R.; Brown, B. L.; Franklin, R.

10.1101/515809 — ecology — Posted on 2019-01-09

2420 The transcription factor TCF7L2 functions as a terminal selector in thalamic and habenular regions of the brain

Lipiec, M. A.; Kozinski, K.; Zajkowski, T.; Dabrowski, M.; Chakraborty, C.; Toval, A.; Ferran, J.; Nagalski, A.; Wisniewska, M. B.

10.1101/515874 — developmental biology — Posted on 2019-01-09

2421 ARID1a protects against steatosis and insulin resistance via PPARalpha-mediated fatty acid oxidation

qu, y.; deng, c.; luo, q.; Shang, x.; Wu, j.; Shi, Y.; Wang, L.; Han, Z.-G.

10.1101/507517 — cell biology — Posted on 2019-01-09

2422 Multiplexed electron microscopy by fluorescent barcoding allows screening for ultrastructural phenotype

Bykov, Y.; Cohen, N.; Gabrielli, N.; Manenschijn, H.; Welsch, S.; Chlanda, P.; Kukulski, W.; Patil, K. R. R.; Schuldiner, M.; Briggs, J. A. G.

10.1101/515841 — cell biology — Posted on 2019-01-09

2423 How does the presence of neural probes affect extracellular potentials?

Buccino, A.; Kuchta, M.; Jaeger, K.; Ness, T.; Berthet, P.; Mardal, K.-A.; Cauwenberghs, G.; Tveito, A.

10.1101/318741 — neuroscience — Posted on 2019-01-09

2424 Sensitive periods for white matter plasticity and reading intervention

Yeatman, J. D.; Huber, E.

10.1101/346759 — neuroscience — Posted on 2019-01-08

2425 Whitening of odor representations by specific network connectivity

Wanner, A. A.; Friedrich, R. W.

10.1101/515411 — neuroscience — Posted on 2019-01-08

2426 Control of MYC-dependent apoptotic threshold by a co-amplified ubiquitin E3 ligase UBR5

Qiao, X.; Liu, Y.; Prada, M. L.; Gupta, A.; Jaiswal, A.; Sharma, M.; Haikala, H. M.; Talvinen, K.; Yetukuri, L.; Pylvänäinen, J. W.; Klefström, J.; Kronqvist, P.; Meinander, A.; Aittokallio, T.; Hietakangas, V.; Eilers, M.; Westermarck, J.

10.1101/515247 — cancer biology — Posted on 2019-01-08

2427 Tarantula phylogenomics: A robust phylogeny of multiple tarantula lineages inferred from transcriptome data sheds light on the prickly issue of urticating setae evolution

Foley, S.; Lueddecke, T.; Chen, D.-Q.; Krehenwinkel, H.; Kuenzel, S.; Longhorn, S. J.; Wendt, I.; von Wirth, V.; Taenzler, R.; Vences, M.; Piel, W. H.

10.1101/501262 — evolutionary biology — Posted on 2019-01-08

2428 Intermittent hormonal therapy shows similar outcome than SOC in ER+ breast cancer preclinical model.

Enriquez Navas, P. M.; Garcia, L.; Abdalah, M.; Stringfield, O.; Luddy, K.; Hassan, S.; Gillies, R. J.; Gatenby, R. A.

10.1101/509158 — cancer biology — Posted on 2019-01-08

2429 Light-mediated circuit switching in the Drosophila neuronal clock network

Schlichting, M.; Weidner, P.; Diaz, M.; Menegazzi, P.; Dalla-Benetta, E.; Helfrich-Foerster, C.; Rosbash, M.

10.1101/515478 — neuroscience — Posted on 2019-01-08

2430 Müllerian mimicry in bumble bees is a transient continuum

Ezray, B. D.; Wham, D. C.; Hill, C.; Hines, H. M.

10.1101/513275 — evolutionary biology — Posted on 2019-01-08

2431 Variational Infinite Heterogeneous Mixture Model for Semi-supervised Clustering of Heart Enhancers

Mehdi, T. F.; Singh, G.; Mitchell, J. A.; Moses, A. M.

10.1101/442392 — bioinformatics — Posted on 2019-01-08

2432 Phenotypic, functional and taxonomic features predict host-pathogen interactions

Liu-Wei, W.; Kafkas, S.; Hoehndorf, R.

10.1101/508762 — bioinformatics — Posted on 2019-01-08

2433 Microsecond Interaural Time Difference Discrimination Restored by Cochlear Implants After Neonatal Deafness

Rosskothen-Kuhl, N.; Buck, A. N.; Li, K.; Schnupp, J. W.

10.1101/498105 — neuroscience — Posted on 2019-01-08

2434 Reorganization in cerebral and cerebellar cortices is not restricted by proximity between body-part representations

Hahamy, A.; Makin, T.

10.1101/439356 — neuroscience — Posted on 2019-01-08

2435 The influence of kinesthetic motor imagery and effector specificity on the long-latency stretch response

Forgaard, C.; Franks, I. M.; Maslovat, D.; Chua, R.

10.1101/510271 — neuroscience — Posted on 2019-01-08

2436 RNAi screen in Tribolium reveals involvement of F-BAR proteins in myoblast fusion and visceral muscle morphogenesis in insects

Schultheis, D.; Schwirz, J.; Frasch, M.

10.1101/397232 — developmental biology — Posted on 2019-01-08

2437 Comparing the aftereffects of motion and causality across visual co-ordinates

Gallagher, R.; Arnold, D. H.

10.1101/499764 — neuroscience — Posted on 2019-01-08

2438 Native CRISPR-Cas mediated in situ genome editing reveals the exquisite interplay of resistance mutations in clinical multidrug resistant Pseudomonas aeruginosa

Xu, Z.; Li, M.; Li, Y.; Cao, H.; Woo, P. C.; Xiang, H.; Yan, A.

10.1101/496711 — microbiology — Posted on 2019-01-08

2439 A novel rationale for targeting FXI: Insights from the hemostastic miRNA targetome for emerging anticoagulant strategies

Nourse, J.; Danckwardt, S.

10.1101/501676 — genomics — Posted on 2019-01-08

2440 Hierarchical Complexity of the Adult Human Structural Connectome

Smith, K.; Bastin, M. E.; Cox, S. R.; Valdes-Hernandez, M. C.; Wiseman, S.; Escudero, J.; Sudlow, C.

10.1101/389569 — systems biology — Posted on 2019-01-08

2441 Qoala-T: A supervised-learning tool for quality control of FreeSurfer segmented MRI data

Klapwijk, E. T.; van de Kamp, F.; van der Meulen, M.; Peters, S.; Wierenga, L. M.

10.1101/278358 — neuroscience — Posted on 2019-01-08

2442 Decoupling of rates of protein synthesis from cell expansion leads to supergrowth

Knapp, B. D.; Odermatt, P.; Rojas, E. R.; Cheng, W.; He, X.; Huang, K. C.; Chang, F.

10.1101/498600 — cell biology — Posted on 2019-01-08

2443 DR-SIP: Protocols for Higher Order Structure Modeling with Distance Restraints- and Cyclic Symmetry-Imposed Packing

Chan, J.; Zou, J.; Chien, C.-H. C.; Pan, R.-L.; Yang, L.-W.

10.1101/500397 — bioinformatics — Posted on 2019-01-08

2444 Sensitivity and Specificity of Information Criteria

Dziak, J. J.; Coffman, D. L.; Lanza, S. T.; Li, R.; Jermiin, L. S.

10.1101/449751 — bioinformatics — Posted on 2019-01-08

2445 Preoptic galanin neuron activation is specific to courtship reproductive tactic in fish with two male morphs

Tripp, J. A.; Salas-Allende, I.; Makowski, A.; Bass, A.

10.1101/515452 — neuroscience — Posted on 2019-01-08

2446 Fundamental Law of Memory Recall

Naim, M.; Katkov, M.; Tsodyks, M.

10.1101/510750 — neuroscience — Posted on 2019-01-08

2447 Genomic Prediction of Complex Disease Risk

Lello, L.; Raben, T. G.; Yong, S. Y.; Tellier, L. C.; Hsu, S. D. H.

10.1101/506600 — genomics — Posted on 2019-01-08

2448 A pseudo-meiotic centrosomal function of TEX12 in cancer

Sandhu, S.; Salmon, L. J.; Hunter, J. E.; Wilson, C. L.; Perkins, N. D.; Hunter, N.; Davies, O. R.; McClurg, U. L.

10.1101/509869 — cell biology — Posted on 2019-01-08

2449 The material properties of naked mole-rat hyaluronan

Kulaberoglu, Y.; Bhushan, B.; Hadi, F.; Chakrabarti, S.; Khaled, W.; Rankin, K.; St. John Smith, E.; Frankel, D.

10.1101/447631 — biophysics — Posted on 2019-01-08

2450 Middle-way flexible docking: Pose prediction using mixed-resolution Monte Carlo in estrogen receptor α

Spiriti, J.; Subramanian, S. R.; Palli, R.; Wu, M.; Zuckerman, D. M.

10.1101/424952 — biophysics — Posted on 2019-01-08

2451 Generating an artificial nest building pufferfish in a cellular automaton through behavior decomposition

Portegys, T. E.

10.1101/478750 — synthetic biology — Posted on 2019-01-08

2452 Adrenergic activation of cardiac preganglionic neurons in nucleus ambiguous relies on persistent sodium current

Aiba, I.; Noebels, J. L.

10.1101/276998 — neuroscience — Posted on 2019-01-08

2453 Distinct contributions of mouse cortical areas to visual discrimination

Zatka-Haas, P.; Steinmetz, N. A.; Carandini, M.; Harris, K. D.

10.1101/501627 — neuroscience — Posted on 2019-01-08

2454 A comprehensive data-driven model of cat primary visual cortex

Antolik, J.; Monier, C.; Davison, A.; Fregnac, Y.

10.1101/416156 — neuroscience — Posted on 2019-01-08

2455 Insulin-Producing Cells Monitor the Temperature and Compensate for Cold-Induced Sleep in Drosophila

Zhang, X.; Cui, X.; Zhu, D.

10.1101/419200 — neuroscience — Posted on 2019-01-08

2456 Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

Howard, D. M.; Adams, M. J.; Clarke, T.-K.; Hafferty, J. D.; Gibson, J.; Shirali, M.; Coleman, J. R. I.; Hagenaars, S. P.; Ward, J.; Wigmore, E. M.; Alloza, C.; Shen, X.; Barbu, M. C.; Xu, E. Y.; Whalley, H. C.; Marioni, R. E.; Porteous, D. J.; Davies, G.; Deary, I. J.; Hemani, G.; Berger, K.; Teismann, H.; Rawal, R.; Arolt, V.; Baune, B. T.; Dannlowski, U.; Domschke, K.; Tian, C.; Hinds, D. A.; 23andMe Research Team, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Trzaskowski, M.; Byrne, E. M.; Ripke, S.; Smith, D. J.; Sullivan, P. F.; Wray, N. R.; Breen,

10.1101/433367 — genetics — Posted on 2019-01-08

2457 Wheat VRN1 and FUL2 play critical and redundant roles in spikelet meristem identity and spike determinacy

Li, C.; Lin, H.; Chen, A.; Lau, M.; Jernstedt, J.; Dubcovsky, J.

10.1101/510388 — developmental biology — Posted on 2019-01-08

2458 Novel strand exchange activity of the human PALB2 DNA Binding Domain and its critical role for DNA repair in cells

Deveryshetty, J.; Ryzhikov, M.; Brahati, N.; Peterlini, T.; Dellaire, G.; Masson, J.-Y.; Korolev, S.

10.1101/495192 — biochemistry — Posted on 2019-01-08

2459 Deep learning for inferring gene relationships from single-cell expression data

Yuan, Y.; Bar-Joseph, Z.

10.1101/365007 — systems biology — Posted on 2019-01-08

2460 RNA polymerase clamp movement aids dissociation from DNA but is not required for RNA release at intrinsic terminators

Bellecourt, M. J.; Ray-Soni, A.; Harwig, A.; Mooney, R. A.; Landick, R.

10.1101/453969 — molecular biology — Posted on 2019-01-08

2461 Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing

Flynn, L. L.; Li, R.; Aung-Htut, M. T.; Pitout, I. L.; Cooper, J. A. L.; Hubbard, A.; Griffiths, L.; Bond, C.; Wilton, S. D.; Fox, A. H.; Fletcher, S.

10.1101/446773 — molecular biology — Posted on 2019-01-08

2462 Phage-encoded cationic antimicrobial peptide used for outer membrane disruption in lysis

Holt, A.; Cahill, J.; Ramsey, J.; O'Leary, C.; Moreland, R.; Martin, C.; Galbadage, D. T.; Sharan, R.; Sule, P.; Bettridge, K.; Xiao, J.; Cirillo, J.; Young, R.

10.1101/515445 — microbiology — Posted on 2019-01-08

2463 Systematic identification of human SNPs affecting regulatory element activity

van Arensbergen, J.; Pagie, L.; FitzPatrick, V.; de Haas, M.; Baltissen, M.; Comoglio, F.; van der Weide, R.; Teunissen, H.; Vosa, U.; Franke, L.; de Wit, E.; Vermeulen, M.; Bussemaker, H.; van Steensel, B.

10.1101/460402 — genomics — Posted on 2019-01-08

2464 Miltefosine increases macrophage cholesterol efflux and inhibits NLRP3-inflammasome assembly and IL-1β release.

Iacano, A. J.; Lewis, H.; Hazen, J. E.; Andro, H.; Smith, J. D.; Gulshan, K.

10.1101/430769 — cell biology — Posted on 2019-01-08

2465 Forecasting cell fate during antibiotic exposure using stochastic gene expression

Rossi, N.; El Meouche, I.; Dunlop, M. J.

10.1101/494161 — systems biology — Posted on 2019-01-08

2466 Complex genetic and epigenetic regulation deviates gene expression from a unifying global transcriptional program

Chagoyen, M.; Poyatos, J. F.

10.1101/390419 — systems biology — Posted on 2019-01-08

2467 Multiplex imaging of quantal glutamate release and presynaptic Ca2+ at multiple synapses in situ

Jensen, T. P.; Zheng, K.; Cole, N.; Marvin, J. S.; Looger, L. L.; Rusakov, D. A.

10.1101/336891 — neuroscience — Posted on 2019-01-08

2468 Pharmacological inhibition of the amino-acid transporter LAT1 demonstrates in vitro anti-neoplastic activity towards medulloblastoma

Cormerais, Y.; Pagnuzzi-Boncompagni, M.; Schrötter, S.; Giuliano, S.; Tambutte, E.; Endou, H.; Wempe, M. F.; Pages, G.; Pouyssegur, J.; Picco, V.

10.1101/428722 — cancer biology — Posted on 2019-01-08

2469 Germline genomic landscapes of breast cancer patients significantly predict clinical outcomes

Milanese, J.-S.; Tibiche, C.; Zou, J.; Han, P.; Meng, Z. G.; Nantel, A.; Drouin, S.; Marcotte, R.; Wang, E.

10.1101/312355 — cancer biology — Posted on 2019-01-08

2470 Assessment of a highly multiplexed RNA sequencing platform and comparison to existing high-throughput gene expression profiling techniques

Reed, E.; Moses, E.; Xiao, X. R.; Liu, G.; Campbell, J.; Perdomo, C.; Monti, S.

10.1101/419838 — bioinformatics — Posted on 2019-01-08

2471 Integrating Hi-C links with assembly graphs for chromosome-scale assembly

Ghurye, J.; Rhie, A.; Walenz, B. P.; Schmitt, A.; Selvaraj, S.; Pop, M.; Phillippy, A. M.; Koren, S.

10.1101/261149 — bioinformatics — Posted on 2019-01-08

2472 TaxonKit: a cross-platform and efficient NCBI taxonomy toolkit

Shen, W.; Xiong, J.

10.1101/513523 — bioinformatics — Posted on 2019-01-08

2473 A biologically driven directional change in susceptibility to global-scale glaciation during the Precambrian-Cambrian transition

Boyle, R.; Loescher, C. R.

10.1101/359422 — paleontology — Posted on 2019-01-08

2474 Detecting M/EEG modular brain states in rest and task

Kabbara, A.; Mohamad, K.; O'Neill, G.; Dujardin, K.; El Traboulsi, Y.; Wendling, F.; Hassan, M.

10.1101/510727 — neuroscience — Posted on 2019-01-08

2475 Cryptococcus deuterogattii VGIIa infection associated with travel to the Pacific Northwest outbreak region in an anti-GM-CSF autoantibody positive patient in the United States

Clancey, S. A.; Ciccone, E. J.; Coelho, M. A.; Davis, J.; Ding, L.; Betancourt, R.; Glaubiger, S.; Lee, Y.; Holland, S. M.; Gilligan, P.; Sung, J.; Heitman, J.

10.1101/493239 — microbiology — Posted on 2019-01-08

2476 Neofunctionalisation of basic helix loop helix proteins occurred when plants colonised the land

Bonnot, C.; Hetherington, A. J.; Champion, C.; Breuninger, H.; Kelly, S.; Dolan, L.

10.1101/514109 — evolutionary biology — Posted on 2019-01-08

2477 Life history evolution and phenotypic plasticity in parasitic eyebrights (Euphrasia, Orobanchaceae)

Twyford, A. D.; Frachon, N.; Wong, E. L. Y.; Metherell, C.; Brown, M. R.

10.1101/362400 — evolutionary biology — Posted on 2019-01-08

2478 A large-scale systemic RNAi screen in the red flour beetle Tribolium castaneum identifies novel genes involved in insect muscle development

Schultheis, D.; Weisskopf, M.; Schaub, C.; Ansari, S.; Dao, V.-A.; Grossmann, D.; Majumdar, U.; Hakeemi, M. S.; Troelenberg, N.; Richter, T.; Schmitt-Engel, C.; Schwirz, J.; Ströhlein, N.; Teuscher, M.; Bucher, G.; Frasch, M.

10.1101/397117 — developmental biology — Posted on 2019-01-08

2479 Single-molecule live-cell imaging reveals parallel pathways of prokaryotic nucleotide excision repair

Ghodke, H.; Ho, H. N.; van Oijen, A. M.

10.1101/515502 — biophysics — Posted on 2019-01-08

2480 Purification of Cross-linked RNA-Protein Complexes by Phenol-Toluol Extraction

Urdaneta, E. C.; Vieira-Vieira, C. H.; Hick, T.; Wessels, H.-H.; Figini, D.; Moschall, R.; Medenbach, J.; Ohler, U.; Granneman, S.; Selbach, M.; Beckmann, B. M.

10.1101/333385 — molecular biology — Posted on 2019-01-08

2481 Tristetraprolin/ZFP36 regulates the turnover of autoimmune-associated HLA-DQ mRNAs

Pisapia, L.; Hamilton, R.; FARINA, F.; D'Agostino, V.; Barba, P.; Strazzullo, M.; Provenzani, A.; Gianfrani, C.; Del Pozzo, G.

10.1101/337907 — molecular biology — Posted on 2019-01-08

2482 Promiscuous targeting of cellular proteins by Vpr drives massive proteomic remodelling in HIV-1 infection

Greenwood, E. J.; Williamson, J. C.; Sienkiewicz, A.; Naamati, A.; Matheson, N. J.; Lehner, P. J.

10.1101/364067 — microbiology — Posted on 2019-01-08

2483 Genomic approaches reveal an endemic sub-population of gray wolves in Southern China

Wang, G.-D.; Zhang, M.; Wang, X.; Yang, M. A.; Cao, P.; Liu, F.; Lu, H.; Feng, X.; Skoglund, P.; Wang, L.; Fu, Q.; Zhang, Y.-P.

10.1101/512921 — evolutionary biology — Posted on 2019-01-08

2484 Single-molecule imaging reveals molecular coupling between transcription and DNA repair in live cells

Ho, H. N.; van Oijen, A. M.; Ghodke, H.

10.1101/515536 — biophysics — Posted on 2019-01-08

2485 Dissociable effects of prediction and integration during language comprehension: Evidence from a large-scale study using brain potentials

Nieuwland, M. S.; Barr, D. J.; Bartolozzi, F.; Busch-Moreno, S.; Darley, E.; Donaldson, D. I.; Ferguson, H. J.; Fu, X.; Heyselaar, E.; Huettig, F.; Husband, E. M.; Ito, A.; Kazanina, N.; Kogan, V.; Kohut, Z.; Kulakova, E.; Meziere, D.; Politzer-Ahles, S.; Rousselet, G.; Rueschemeyer, S.-A.; Segaert, K.; Tuomainen, J.; Von Grebmer Zu Wolfsthurn, S.

10.1101/267815 — neuroscience — Posted on 2019-01-08

2486 Quantifying spatiotemporal dynamics and noise in absolute microbiota abundances using replicate sampling

Ji, B. W.; Sheth, R. U.; Dixit, P. D.; Wang, H. H.; Vitkup, D.

10.1101/310649 — microbiology — Posted on 2019-01-08

2487 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linner, R.; Biroli, P.; Kong, E.; Meddens, S. F. W.; Wedow, R.; Fontana, M. A.; Lebreton, M.; Abdellaoui, A.; Hammerschlag, A. R.; Nivard, M. G.; Okbay, A.; Rietveld, C. A.; Timshel, P. N.; Tino, S. P.; Trzaskowski, M.; de Vlaming, R.; Zünd, C. L.; Bao, Y.; Buzdugan, L.; Caplin, A. H.; Chen, C.-Y.; Eibich, P.; Fontanillas, P.; Gonzalez, J. R.; Joshi, P. K.; Karhunen, V.; Kleinman, A.; Levin, R. Z.; Lill, C. M.; Meddens, G. A.; Muntane, G.; Sanchez-Roige, S.; van Rooij, F. J.; Taskesen, E.; Wu, Y.; Zhang, F.; 23andMe Research Team, ; eQTLgen Consortium, ; International Cannabis Cons

10.1101/261081 — genetics — Posted on 2019-01-08

2488 Otx2 signals from the choroid plexus to regulate adult neurogenesis

Planques, A.; Oliveira Moreira, V.; Dubreuil, C.; Prochiantz, A.; Di Nardo, A. A.

10.1101/243659 — neuroscience — Posted on 2019-01-08

2489 Time- and cost-efficient high-throughput transcriptomics enabled by Bulk RNA Barcoding and sequencing

Alpern, D.; Gardeux, V.; Russeil, J.; Deplancke, B.

10.1101/256594 — genomics — Posted on 2019-01-08

2490 High-level correction of the sickle mutation amplified in vivo during erythroid differentiation

Magis, W.; DeWitt, M. A.; Wyman, S. K.; Vu, J. T.; Heo, S.-J.; Shao, S. J.; Hennig, F.; Romero, Z. G.; Campo-Fernandez, B.; McNeill, M.; Rettig, G. R.; Sun, Y.; Lau, P. J.; Wang, Y.; Behlke, M. A.; Kohn, D. B.; Boffelli, D.; Walters, M. C.; Corn, J. E.; Martin, D. I. K.

10.1101/432716 — genetics — Posted on 2019-01-08

2491 Discovery of biased orientation of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2019-01-08

2492 Defining the dynamic chromatin landscape of nephron progenitors

Hilliard, S.; Song, R.; Liu, H.; Chen, C.-h.; Li, Y.; Baddoo, M.; Flemington, E.; Wanek, A.; Kolls, J.; Saifudeen, Z.; El-Dahr, S. S.

10.1101/515429 — developmental biology — Posted on 2019-01-08

2493 Erythroid differentiation displays a peak of energy consumption concomitant with glycolytic metabolism rearrangements

Richard, A.; Vallin, E.; Romestaing, C.; Roussel, D.; Gandrillon, O.; Gonin-Giraud, S.

10.1101/514752 — cell biology — Posted on 2019-01-08

2494 Comprehensive substrate specificity profiling of the human nek kinome reveals unexpected signaling outputs

van de Kooij, B.; Creixell, P.; van Vlimmeren, A.; Joughin, B.; Miller, C. J.; Haider, N.; Linding, R.; Stambolic, V.; Turk, B. E.; Yaffe, M. B.

10.1101/515221 — biochemistry — Posted on 2019-01-08

2495 Dynamic Predictive Accuracy of Electrocardiographic Biomarkers of Sudden Cardiac Death within a Survival Framework: The Atherosclerosis Risk in Communities (ARIC) study

Perez-Alday, E.; Bender, A.; Li-Pershing, Y.; German, D.; Mai, T.; Mukundan, S.; Thomas, J.; Hamilton, C.; Tereshchenko, L.

10.1101/514380 — epidemiology — Posted on 2019-01-08

2496 Mosaic origin of the eukaryotic kinetochore

van Hooff, J. J.; Tromer, E.; Kops, G.; Snel, B.

10.1101/514885 — cell biology — Posted on 2019-01-08

2497 Post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced

Banerjee, A.; Percival-Smith, A.

10.1101/512962 — biochemistry — Posted on 2019-01-08

2498 The effect of pre-analytical conditions on blood metabolomics in epidemiological studies

Santos Ferreira, D. L.; Maple, H.; Goodwin, M.; Brand, J. S.; Yip, V.; Min, J. L.; Groom, A.; Lawlor, D. A.; Ring, S.

10.1101/513903 — epidemiology — Posted on 2019-01-08

2499 Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

Ahola-Olli, A. V.; Mustelin, L.; Kalimeri, M.; Kettunen, J.; Jokelainen, J.; Auvinen, J.; Puukka, K.; Havulinna, A. S.; Lehtimaki, T.; Kahonen, M.; Juonala, M.; Keinanen-Kiukaanniemi, S.; Salomaa, V.; Perola, M.; Jarvelin, M.-R.; Ala-Korpela, M.; Raitakari, O.; Würtz, P.

10.1101/513648 — epidemiology — Posted on 2019-01-08

2500 Myosin Orientation in a Muscle Fiber Determined with High Angular Resolution Using Bifunctional Spin Labels

Savich, Y.; Binder, B. P.; Thompson, A. R.; Thomas, D. D.

10.1101/513556 — biophysics — Posted on 2019-01-08

2501 Minimal membrane interactions conferred by Rheb C-terminal farnesylation are essential for mTORC1 activation

Ferguson, S. M.; Angarola, B.

10.1101/513473 — cell biology — Posted on 2019-01-08

2502 What drives phenotypic divergence among coral clonemates?

Devlin-Durante, M.; Baums, I.; Williams, D. W.; Kemp, D.

10.1101/514430 — evolutionary biology — Posted on 2019-01-08

2503 Extracellular mycobacterial DNA triggers Caspase-11-dependent pyroptosis of infected macrophages and drives disease progression

Varela, M.; van der Vaart, M.; Groenewoud, A.; Meijer, A. H.

10.1101/514125 — immunology — Posted on 2019-01-08

2504 Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking

Lorenz-Guertin, J. M.; Bambino, M. J.; Das, S.; Weintraub, S. T.; Jacob, T. C.

10.1101/514133 — neuroscience — Posted on 2019-01-08

2505 Contesting the evidence for -1 frameshifting in immune-functioning C-C chemokine receptor 5 (CCR5) - the HIV-1 co-receptor

Khan, Y. A.; Loughran, G.; Atkins, J. F.

10.1101/513333 — molecular biology — Posted on 2019-01-08

2506 Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

Thompson, D.; Genovese, G.; Halvardson, J.; Ulirsch, J.; Wright, D.; Terao, C.; Davidsson, O.; Day, F.; Sulem, P.; Jiang, Y.; Danielsson, M.; Davies, H.; Dennis, J.; Dunlop, M.; Easton, D.; Fisher, V.; Zink, F.; Houlston, R.; Ingelsson, M.; Kar, S.; Kerrison, N.; Kristjansson, R.; Li, R.; Loveday, C.; Mattisson, J.; McCarroll, S.; Murakami, Y.; Murray, A.; Olszewski, P.; Rychlicka-Buniowska, E.; Scott, R.; Thorsteinsdottir, U.; Tomlinson, I.; Torabi Moghadam, B.; Turnbull, C.; Wareham, N.; Gudbjartsson, D.; INTEGRAL-ILCCO, ; The Breast Cancer Association Consortium, ; CIMBA, ; The Endometri

10.1101/514026 — genetics — Posted on 2019-01-08

2507 Transcriptomic basis and evolution of the ant social interactome

Warner, M. R.; Mikheyev, A. S.; Linksvayer, T. A.

10.1101/514356 — evolutionary biology — Posted on 2019-01-08

2508 Joint seasonality in geographic and ecological spaces, illustrated with a partially migratory bird

Basille, M.; Watling, J.; Romanach, S.; Borkhataria, R.

10.1101/514349 — ecology — Posted on 2019-01-08

2509 Dissecting the energetics of subunit rotation in the ribosome

Levi, M.; Whitford, P. C.

10.1101/514448 — biophysics — Posted on 2019-01-08

2510 A quantitative medico-botanical expedition of Fairy Meadows National Park, Diamir, Gilgit Baltistan, Pakistan

Wali, R.; Rahman, K.; Raja, N. I.; Qureshi, R.; Mashwani, Z.-u.-R.

10.1101/507848 — plant biology — Posted on 2019-01-08

2511 Contribution of Lateral Gene Transfer to the evolution of the eukaryotic fungus Piromyces sp. E2: Massive bacterial transfer of genes involved in carbohydrate metabolism

Duarte, I.; Huynen, M. A.

10.1101/514042 — evolutionary biology — Posted on 2019-01-08

2512 Bacterial community changes with cryoconite granule size and their susceptibility to exogenous nutrients on 10 glaciers in northwestern Greenland

Uetake, J.; Nagatsuka, N.; Onuma, Y.; Takeuchi, N.; Motoyama, H.; Aoki, T.

10.1101/514083 — ecology — Posted on 2019-01-08

2513 Mapping Structure and Biological Functions within Mesenchymal Bodies using Microfluidics

Sart, S.; Tomasi, R. F. X.; Barizien, A.; Amselem, G.; Cumano, A.; Baroud, C. N.

10.1101/514158 — cell biology — Posted on 2019-01-08

2514 The crystal structure of Klebsiella pneumoniae FeoA reveals a site for protein-protein interactions

Linkous, R. O.; Sestok, A. E.; Smith, A. T.

10.1101/514059 — biochemistry — Posted on 2019-01-08

2515 Nonlinear transfer and temporal gain control in ON bipolar cells

Deshmukh, N.; Berry, M. J.

10.1101/514364 — neuroscience — Posted on 2019-01-08

2516 Parallel Visual Circuitry in a Basal Chordate

Kourakis, M.; Borba, C.; Zhang, A.; Newman-Smith, E.; Salas, P.; Manjunath, B.; Smith, W.

10.1101/514422 — neuroscience — Posted on 2019-01-08

2517 Class II contact-dependent growth inhibition (CDI) systems allow for broad-range cross-species toxin delivery

Virtanen, P.; Wäneskog, M.; Koskiniemi, S.

10.1101/514810 — evolutionary biology — Posted on 2019-01-08

2518 A quantitative medico-botanical expedition of Fairy Meadows National Park, Diamir, Gilgit Baltistan, Pakistan

Wali, R.; Rahman, K.; Raja, N. I.; Qureshi, R.; Mashwani, Z.-u.-R.

10.1101/507848 — plant biology — Posted on 2019-01-08

2519 Efficacy and Safety of Immunosuppressive Treatment in IgA Nephropathy: A Meta-analysis of Randomized Controlled Trials

Zhang, Z.; Yang, Y.; Jiang, S.-m.; Li, W.-g.

10.1101/515023 — immunology — Posted on 2019-01-08

2520 First report of enhanced contents of nine macro- and micronutrients in gymnosperms via arbuscular mycorrhizal fungi

Franco, A.; Perez-Moreno, J.; Sanchez-Viveros, G.; Cerdan, C.; Almaraz, J.; Cetina-Alcala, V.; Alarcon, A.

10.1101/515031 — ecology — Posted on 2019-01-08

2521 Immigration and establishment of urban Trypanosoma cruzi populations

Berry, A. S. F.; Salazar-Sanchez, R.; Castillo-Neyra, R.; Borrini-Mayori, K.; Chipana-Ramos, C.; Vargas-Maquera, M.; Ancca-Juarez, J.; Naquira-Velarde, C.; Levy, M. Z.; Brisson, D.; Danitza Pamo,Jose Ylla,Gabriela Bustamante,Victor Quispe,Amparo Toledo,Juan Cornejo,Fernando Chavez,,

10.1101/515049 — evolutionary biology — Posted on 2019-01-08

2522 The semantic segmentation approach for normal and pathologic tympanic membrane using deep learning

Seok, J.; Song, J.-J.; Koo, J.-W.; Hee Chan, K.; Choi, B. Y.

10.1101/515007 — bioinformatics — Posted on 2019-01-08

2523 Cooperation and Stability for Complex Systems in Resource Limited Environments

Butler, S.; O'Dwyer, J. P.

10.1101/514018 — ecology — Posted on 2019-01-08

2524 Deep-sea megabenthos communities of the Eurasian Central Arctic are influenced by ice-cover and sea-ice algal falls

Rybakova, E.; Kremenetskaia, A.; Vedenin, A.; Boetius, A.; Gebruk, A.

10.1101/515015 — ecology — Posted on 2019-01-08

2525 WNT/β-CATENIN modulates the axial identity of ES derived human neural crest

Gomez, G. A.; Prasad, M. S.; Wong, M.; Charney, R. M.; Shelar, P.; Sandhu, N.; Hackland, J.; Hernandez, J. C.; Leung, A. W.; Garcia-Castro, M. I.

10.1101/514570 — developmental biology — Posted on 2019-01-08

2526 NRF2-dependent metabolic reprogramming is required for tumor recurrence following oncogene inhibition

Fox, D. B.; Lupo, R.; Noteware, L. C.; Newcomb, R.; Liu, J.; Locasale, J. W.; Hirschey, M. D.; Alvarez, J. V.

10.1101/513994 — cancer biology — Posted on 2019-01-08

2527 A single droplet digital PCR for ESR1 activating mutations detection in plasma

Jeannot, E.; Darrigues, L.; Michel, M.; Stern, M.-H.; Pierga, J.-Y.; Rampanou, A.; Melaabi, S.; Benoist, C.; Bieche, I.; Vincent-Salomon, A.; El Ayachy, R.; Noret, A.; Epaillard, N.; Cabel, L.; Bidard, F.-C.; Proudhon, C.

10.1101/507608 — cancer biology — Posted on 2019-01-08

2528 MS-EmpiRe utilizes peptide-level noise distributions for ultra sensitive detection of differentially abundant proteins

Ammar, C.; Gruber, M.; Csaba, G.; Zimmer, R.

10.1101/514000 — bioinformatics — Posted on 2019-01-08

2529 Cortical and Cardiovascular Regulation Support Adaptation to Ambient Sound Environment

Hao, Y.; Gupta, D.; Sun, Q.; Yao, L.

10.1101/513937 — neuroscience — Posted on 2019-01-08

2530 Shigella flexneri adherence factor expression in in vivo-like conditions

Chanin, R. B.; Nickerson, K. P.; Llanos-Chea, A.; Sistrunk, J. R.; Rasko, D.; Vijaya Kumar, D. K.; De La Parra, J.; Auclair, J.; Ding, J.; Li, K.; Dogiparthi, S.; Kusber, B.; Faherty, C. S.

10.1101/514679 — microbiology — Posted on 2019-01-08

2531 Collagen Density Modulates the Immunosuppressive Functions of Tumor-Associated Macrophages

Larsen, A. M.; Kuczek, D. E.; Kalvisa, A.; Siersbaek, M. S.; Thorseth, M.-L.; Carretta, M.; Groentved, L.; Vang, O.; Madsen, D. H.

10.1101/513986 — immunology — Posted on 2019-01-08

2532 Systematic Development Of Sandwich Immunoassays For The Plasma Secretome

Haeussler, R. S.; Bendes, A.; Iglesias, M.; Sanchez-Rivera, L.; Dodig-Crnkovic, T.; Bystrom, S.; Fredolini, C.; Birgersson, E.; Dale, M.; Edfors, F.; Fagerberg, L.; Rockberg, J.; Tegel, H.; Uhlen, M.; Qundos, U.; Schwenk, J. M.

10.1101/511907 — biochemistry — Posted on 2019-01-08

2533 Contribution of pretomanid to novel regimens containing bedaquiline with either linezolid or moxifloxacin and pyrazinamide in murine models of tuberculosis

Xu, J.; Li, S.-Y.; Almeida, D.; Tasneen, R.; Barnes-Boyle, K.; Converse, P. J.; M Upton, A.; Mdluli, K.; Fotouhi, N.; Nuermberger, E.

10.1101/514661 — pharmacology and toxicology — Posted on 2019-01-08

2534 Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.

King, E. A.; Davis, J. W.; Degner, J. F.

10.1101/513945 — genetics — Posted on 2019-01-08

2535 CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain.

Thomas, L. W.; Stephen, J. M.; Esposito, C.; Hoer, S.; Antrobus, R.; Ahmed, A.; Al-Habib, H.; Ashcroft, M.

10.1101/513770 — cell biology — Posted on 2019-01-07

2536 Compartmentalized nonsense-mediated mRNA decay regulates synaptic plasticity and cognitive function via GluR1 signaling

Notaras, M.; Allen, M.; Longo, F.; Volk, N.; Toth, M.; Jeon, N. L.; Klann, E.; Colak, D.

10.1101/389585 — neuroscience — Posted on 2019-01-07

2537 Recruitment and disruption of value encoding during alcohol seeking

Ottenheimer, D.; Wang, K.; Haimbaugh, A.; Janak, P. H.; Richard, J. M.

10.1101/513911 — neuroscience — Posted on 2019-01-07

2538 The antimicrobial peptide Defensin cooperates with Tumour Necrosis Factor to drive tumour cell death in Drosophila

Parvy, J.-P.; Yu, Y.; Dostalova, A.; Kondo, S.; Kurjan, A.; Bulet, P.; Lemaitre, B.; Vidal, M.; Cordero, J.

10.1101/513747 — cancer biology — Posted on 2019-01-07

2539 Identification of a novel therapeutic agent for Inflammatory Bowel Disease guided by systems medicine

Lloyd, K.; Papoutsopoulou, S.; Smith, E.; Stegmaier, P.; Bergey, F.; Morris, L.; Kittner, M.; England, H.; Spiller, D.; White, M. H.; Duckworth, C. A.; Campbell, B. J.; Poroikov, V.; Martins dos Santos, V.; Kel, A.; Müller, W.; Pritchard, D. M.; Probert, C.; Burkitt, M.; The SysmedIBD Consortium,

10.1101/513838 — systems biology — Posted on 2019-01-07

2540 The interplay between multisensory integration and perceptual decision making

Mercier, M. R.; Cappe, C.

10.1101/513630 — neuroscience — Posted on 2019-01-07

2541 Altered Motor Development Following Late Gestational Alcohol and Cannabinoid Exposure in Rats

Breit, K. R.; Zamudio, B.; Thomas, J. D.

10.1101/513713 — neuroscience — Posted on 2019-01-07

2542 An EEG study of detection without localisation in change blindness

Scrivener, C. L.; Malik, A.; Marsh, J.; Lindner, M.; Roesch, E.

10.1101/513697 — neuroscience — Posted on 2019-01-07

2543 Virus-host coexistence in phytoplankton through the genomic lens

Yau, S.; Krasovec, M.; Rombauts, S.; Groussin, M.; Benites, L. F.; Vancaester, E.; Aury, J.-M.; Derelle, E.; Desdevises, Y.; Escande, M.-L.; Grimsley, N.; Guy, J.; Moreau, H.; Sanchez-Brosseau, S.; van de Peer, Y.; Vandepoele, K.; Gourbiere, S.; Piganeau, G.

10.1101/513622 — evolutionary biology — Posted on 2019-01-07

2544 From individuals to populations: How intraspecific competition shapes thermal reaction norms

Mallard, F.; Le Bourlot, V.; Le Coeur, C.; Avnaim, M.; Claessen, D.; Tully, T.

10.1101/513739 — ecology — Posted on 2019-01-07

2545 Comparative analysis of Synthetic Physical Interactions with the yeast centrosome

Howell, R. S.; Csikasz-Nagy, A.; Thorpe, P. H.

10.1101/514166 — cell biology — Posted on 2019-01-07

2546 Hundreds of yeast mRNAs form a separately addressable, translation elongation-controlled regulon

Kazana, E.; von der Haar, T.

10.1101/513705 — molecular biology — Posted on 2019-01-07

2547 Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse

Cross, S. H.; Mckie, L.; Keighren, M.; West, K.; Thaung, C.; Davey, T.; Jackson, I. J.

10.1101/513846 — molecular biology — Posted on 2019-01-07

2548 Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus

Rose, C.; Dyer, N. A.; Casas-Sanchez, A.; Beckett, A. J.; Solorzano, C.; Middlehurst, B.; Marcello, M.; Lehane, M. J.; Prior, I. A.; Acosta-Serrano, A.

10.1101/513689 — microbiology — Posted on 2019-01-07

2549 Craniofacial allometry is a rule in evolutionary radiations of placentals

Cardini, A.

10.1101/513754 — evolutionary biology — Posted on 2019-01-07

2550 The Effects of Alcohol and Cannabinoid Exposure during the Brain Growth Spurt on Behavioral Development in Rats

Breit, K. R.; Zamudio, B.; Thomas, J. D.

10.1101/513796 — neuroscience — Posted on 2019-01-07

2551 Cyclin A2/Cdk1 is Essential for the in vivo S Phase Entry by Phosphorylating Top2a.

Jin, M.; Hu, R.; Xu, B.; Huang, W.; Wang, H.; Chen, B.; He, J.; Cao, Y.

10.1101/513861 — developmental biology — Posted on 2019-01-07

2552 Multiple splitting of droplets using multi-furcating microfluidic channels

Li, Z.; Li, L.; Liao, M.; He, L.; Wu, P.

10.1101/513812 — biophysics — Posted on 2019-01-07

2553 Bacterioplankton dynamics driven by inter-annual variation in phytoplankton spring bloom communities in the Baltic Sea

Camarena Gomez, M. T.; Ruiz-Gonzalez, C.; Piiparinen, J.; Lipsewers, T.; Sobrino, C.; Logares, R.; Spilling, K.

10.1101/513606 — microbiology — Posted on 2019-01-07

2554 Perceptions and Prospects in Life Sciences in a Heterogenous Latin American Population

Ferreira, L. M. R.; Carosso, G. A.; Lopez-Videla, B.; Vaca Diez, G.; Rivera-Betancourt, L. I.; Rodriguez, Y.; Ordonez, D. G.; Montellano Duran, N.; Alatriste-Gonzalez, D. K.; Vacaflores, A.; Bohorquez, S.; Gonzalez Auza, L.; Schuetz, C.; Alexander-Savino, C.; Gandarilla Cuellar, O.; Mostajo Radji, M. A.

10.1101/514216 — scientific communication and education — Posted on 2019-01-07

2555 Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli

Davies, T. J.; Stoesser, N.; Sheppard, A. E.; Abuoun, M.; Fowler, P. W.; Swann, J.; Quan, P.; Griffiths, D.; Vaughan, A.; Morgan, M.; Phan, H. T. T.; Jeffery, K. J.; Andersson, M.; Ellington, M.; Ekelund, O.; Mathers, A.; Bonomo, R.; Woodford, N.; Crook, D. W.; Peto, T. E.; Anjum, M.; Walker, A. S.

10.1101/511402 — microbiology — Posted on 2019-01-07

2556 MeshMonk: Open-source large-scale intensive 3D phenotyping

White, J. D.; Ortega-Castrillon, A.; Matthews, H.; Zaidi, A. A.; Ekrami, O.; Snyders, J.; Fan, Y.; Penington, A.; Van Dongen, S.; Shriver, M. D.; Claes, P.

10.1101/491639 — evolutionary biology — Posted on 2019-01-07

2557 Ecological modeling of Long Interspersed elements reveals footprints of evolution and a role of chromatin in shaping their genome landscape in mammals.

Vitali, S.; Criscione, S.; Sala, C.; Do Valle, I.; Giampieri, E.; Neretti, N.; Castellani, G.

10.1101/513572 — biophysics — Posted on 2019-01-07

2558 How conspicuous are peacock eyespots and other colorful feathers in the eyes of mammalian predators?

Kane, S. A.; Wang, Y.; Fang, R.; Lu, Y.; Dakin, R.

10.1101/514240 — zoology — Posted on 2019-01-07

2559 Cycloheximide-Producing Streptomyces Associated with Xyleborinus saxesenii and Xyleborus affinis Fungus-Farming Ambrosia Beetles

Grubbs, K. J.; Surup, F.; Biedermann, P. H. W.; McDonald, B. R.; Klassen, J. L.; Carlson, C. M.; Clardy, J.; Currie, C. R.

10.1101/511493 — microbiology — Posted on 2019-01-07

2560 Epigenetic switching as a strategy for quick adaptation while constraining biochemical noise

Gomez-Schiavon, M.; Buchler, N. E.

10.1101/072199 — evolutionary biology — Posted on 2019-01-07

2561 Acceptability of active case finding with a seed-and-recruit model to improve tuberculosis case detection and linkage to treatment in Cambodia: a qualitative study

Tuot, S.; Teo, A. K. J.; Cazabon, D.; Sok, S.; Ung, M.; Ly, S.; Choub, S. C.; Yi, S.

10.1101/514208 — epidemiology — Posted on 2019-01-07

2562 Growth-rate and protein-synthesis dynamics of single Bacillus subtilis cells along their cell-cycle

Nordholt, N.; van Heerden, J. H.; Bruggeman, F. J.

10.1101/510925 — microbiology — Posted on 2019-01-07

2563 The Nopp140 gene in Drosophila melanogaster displays length polymorphisms in its large repetitive second exon

Baral, S. S.; DiMario, P.

10.1101/513978 — genetics — Posted on 2019-01-07

2564 CRISPR-based platform for multimodal genetic screens in human iPSC-derived neurons

Tian, R.; Gachechiladze, M. A.; Ludwig, C. H.; Laurie, M. T.; Hong, J. Y.; Nathaniel, D.; Prabhu, A. V.; Fernandopulle, M. S.; Patel, R.; Ward, M. E.; Kampmann, M.

10.1101/513309 — cell biology — Posted on 2019-01-07

2565 Myosin Orientation in a Muscle Fiber Determined with High Angular Resolution Using Bifunctional Spin Labels

Savich, Y.; Binder, B. P.; Thompson, A. R.; Thomas, D. D.

10.1101/513556 — biophysics — Posted on 2019-01-07

2566 Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence

Pislar, A.; Tratnjek, L.; Glavan, G.; Zidar, N.; Zivin, M.; Kos, J.

10.1101/513671 — molecular biology — Posted on 2019-01-07

2567 RNAIndel: a machine-learning framework for discovery of somatic coding indels using tumor RNA-Seq data

Hagiwara, K.; Ding, L.; Edmonson, M. N.; Rice, S. V.; Newman, S.; Meshinchi, S.; Ries, R. E.; Rusch, M.; Zhang, J.

10.1101/512749 — bioinformatics — Posted on 2019-01-07

2568 Species-specific enhancement of enterohemorrhagic E. Coli pathogenesis mediated by microbiome metabolites

Tovaglieri, A.; Sontheimer-Phelps, A.; Geirnaert, A.; Prantil-Baun, R.; Camacho, D. M.; Chou, D. B.; Jalili-Firoozinezhad, S.; de Wouters, T.; Kasendra, M.; Super, M.; Cartwright, M.; Richmond, C. A.; Breault, D. T.; Lacroix, C.; Ingber, D. E.

10.1101/513614 — bioengineering — Posted on 2019-01-07

2569 Airway epithelial integrin β4 suppresses allergic inflammation by decreasing CCL17 production

Chi, L.; Yuan, L.; Zhang, X.; Yang, M.; Zou, Y.; Xiang, Y.; Qu, X.; Liu, H.; Du, X.; Wang, L.; Wu, S.; Wu, M.; Qin, L.; Qin, Q.; Qin, X.

10.1101/513499 — immunology — Posted on 2019-01-07

2570 TargetSeeker-MS: A computational method for drug target discovery using protein separation coupled to mass spectrometry

Lavallee-Adam, M.; Pelletier, A.; Diedrich, J. K.; Low, W.; Pinto, A. F.; Martinez-Bartolome, S.; Petrascheck, M.; Moresco, J. J.; Yates, J. R.

10.1101/513663 — bioinformatics — Posted on 2019-01-07

2571 LncRNA Dnmt3aos regulates Dnmt3a expression leading to aberrant DNA methylation in macrophage polarization

Li, X.; Zhang, Y.; Zhang, M.; Kong, X.; Yang, H.; Zhong, M.; Pei, W.; Xu, Y.; Zhu, X.; Chen, T.; Ye, J.; Lv, K.

10.1101/514307 — cell biology — Posted on 2019-01-07

2572 Stochastic neural field model of stimulus-dependent variability in cortical neurons

Bressloff, P. C.

10.1101/514315 — neuroscience — Posted on 2019-01-07

2573 Dynamics, cariogenicity, and geographic distribution of Streptococcus mutans adhesin types suggest adaptation to individual hosts

Sheng, N.; Esberg, A.; marell, l.; Johansson, E.; Källestal, C.; Strömberg, N.

10.1101/514265 — microbiology — Posted on 2019-01-07

2574 Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats

Song, D.; Yin, L.; Wang, C.; Wen, X.

10.1101/514299 — molecular biology — Posted on 2019-01-07

2575 High-quality, genome-wide SNP genotypic data for pedigreed germplasm of the diploid outbreeding species apple, peach, and sweet cherry through a common workflow

Vanderzande, S.; Howard, N. P.; Cai, L.; Da Silva Linge, C.; Antanaviciute, L.; Bink, M. C.; Kruisselbrink, J. W.; Bassil, N.; Gasic, K.; Iezzoni, A.; van de Weg, E.; Peace, C.

10.1101/514281 — genetics — Posted on 2019-01-07

2576 Implementation and Integration of Microbial Source Tracking in a River Watershed Monitoring Plan

Balleste, E.; Demeter, K.; Masterson, B.; Timoneda, N.; Meijer, W. G.

10.1101/514257 — ecology — Posted on 2019-01-07

2577 Pain sensitivity and athletic performance

zeller, l.; Shimoni, N.; Vodonos, A.; Sagy, I.; Barski, L.; Buskila, D.

10.1101/514224 — physiology — Posted on 2019-01-07

2578 Consideration of species-specific diatom indicators of anthropogenic stress in the Great Lakes

Reavie, E.; Cai, M.

10.1101/514273 — ecology — Posted on 2019-01-07

2579 Preparation of Organ Scaffolds by Decellularization of Pancreas and Re-functionalization

K, U. C.; Tripathi, R.; T, A. R.; N, S.; Parlikar, V. K.; VB, S.; Rangaraj, N.; Jerald, M. K.; Singh, S.

10.1101/513465 — cell biology — Posted on 2019-01-07

2580 VGF in cerebrospinal fluid, when combined with conventional biomarkers, enhances prediction of conversion from mild cognitive impairment to Alzheimer Disease.

Llano, D. A.; Devanarayan, P.; Devanarayan, V.

10.1101/512939 — neuroscience — Posted on 2019-01-07

2581 Coupled fast and slow feedbacks lead to continual evolution: A general modeling approach

Wortel, M. T.; Peters, H.; Stenseth, N. C.

10.1101/513416 — evolutionary biology — Posted on 2019-01-07

2582 MAGICACT: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data.

Roopra, A.

10.1101/492744 — bioinformatics — Posted on 2019-01-07

2583 Dissociating orexin-dependent and -independent functions of orexin neurons using novel orexin-Flp knock-in mice

Chowdhury, S.; Hung, C. J.; Izawa, S.; Inutsuka, A.; Kawamura, M.; Kawashima, T.; Bito, H.; Imayoshi, I.; Abe, M.; Sakimura, K.; Yamanaka, A.

10.1101/512947 — neuroscience — Posted on 2019-01-07

2584 Reference genome for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine

Borgers, K.; Ou, J.-Y.; Zheng, P.-X.; Tiels, P.; Van Hecke, A.; Plets, E.; Michielsen, G.; Festjens, N.; Callewaert, N.; Lin, Y.-C.

10.1101/513408 — microbiology — Posted on 2019-01-07

2585 Compressive Stress Enhances Invasive Phenotype of Cancer Cells via Piezo1 Activation

Luo, M.; Ho, K. K. Y.; Tong, Z.; Deng, L.; Liu, A. P.

10.1101/513218 — cell biology — Posted on 2019-01-07

2586 Pancreatic tumor organoids for modeling in vivo drug response and discovering clinically-actionable biomarkers

10.1101/513267 — cancer biology — Posted on 2019-01-07

2587 Gene Panel Sequencing in a Chinese High-risk Breast Cancer Cohort

Zhang, X.; Wang, X.; Song, B.; Shao, K.; Li, G.; Jian, W.; Lin, C.; Wang, M.; Ye, X.; Xie, J.; Xia, B.; Xu, S.; Cao, B.; Xiao, L.; Zhang, Z.; Liu, M.; Fang, E.; Jin, H.; Wei, X.; Dean, M.; Wang, J.; Yang, H.; Wang, X.; Zhu, S.; Hou, Y.; Pang, D.

10.1101/513317 — cancer biology — Posted on 2019-01-07

2588 Serodiagnostic potential of synthetic peptides derived from African swine fever virus putative protein pCP312R

Ochwo, S.; Atuhaire, D. K.; Afayoa, M.; Kisseka, M.; Magambo, P. K.; Okuni, J. B.; Olaho-Mukani, W.; Ojok, L.

10.1101/512772 — immunology — Posted on 2019-01-07

2589 Combination image flow cytometry for single-cell analysis reveals novel methods for isolating subsets of megakaryocyte progenitor populations

Bush, L. M.; Marvin, J. E.; Deans, T. L.

10.1101/512442 — cell biology — Posted on 2019-01-07

2590 A rabbit monoclonal antibody against the antiviral and cancer genomic DNA mutating enzyme APOBEC3B

Brown, W.; Law, E.; Carpenter, M.; Argyris, P.; Levin-Klein, R.; Ranum, A.; Molan, A.; Forster, C.; Anderson, B.; Lackey, L.; Harris, R.

10.1101/513341 — cancer biology — Posted on 2019-01-07

2591 Effects of high iodine containing low osmolar contrast agent (visipaque) on thyroid function tests

Niknamian, S.

10.1101/513291 — pathology — Posted on 2019-01-07

2592 In-silico Exploration of Mouse Brain Dynamics by Stimulation explains Functional Networks and Sensory Processing

Spiegler, A.; Karimi Abadchi, J.; Mohajerani, M. H.; Jirsa, V. K.

10.1101/512871 — neuroscience — Posted on 2019-01-07

2593 GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice

Chowdhury, S.; Matsubara, T.; Miyazaki, T.; Ono, D.; Abe, M.; Sakimura, K.; Yamanaka, A.

10.1101/512954 — neuroscience — Posted on 2019-01-07

2594 Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B

Shi, K.; Demir, O.; Carpenter, M. A.; Banerjee, S.; Harki, D. A.; Amaro, R. E.; Harris, R. S.; Aihara, H.

10.1101/513366 — biochemistry — Posted on 2019-01-07

2595 Berry and pip form covariation in wild and domesticated grapevines: eco-evo-devo implications and archaeobotanical perspectives

Bonhomme, V.; Picq, S.; Ivorra, S.; Evin, A.; Pastor, T.; Bacilieri, R.; Lacombe, T.; Figueiral, I.; Terral, J.-F.; Bouby, L.

10.1101/513036 — plant biology — Posted on 2019-01-07

2596 Intrinsic plasticity of cerebellar Purkinje cells in motor learning circuits

Jang, D. C.; Shim, H. G.; Kim, S. J.

10.1101/513283 — neuroscience — Posted on 2019-01-07

2597 Internally coupled middle ears enhance the range of interaural time differences heard by the chicken

Koeppl, C.

10.1101/512715 — neuroscience — Posted on 2019-01-07

2598 Soil Bacterial and Fungal Response to Wildfires in the Canadian Boreal Forest Across a Burn Severity Gradient

Whitman, T.; Whitman, E.; Woolet, J.; Flannigan, M. D.; Thompson, D. K.; Parisien, M.-A.

10.1101/512798 — microbiology — Posted on 2019-01-07

2599 Whole Genome Doubling mitigates Muller’s Ratchet in Cancer Evolution

Lopez, S.; Lim, E.; Huebner, A.; Dietzen, M.; Mourikis, T.; Watkins, T. B.; Rowan, A.; Dewhurst, S. M.; Birkbak, N. J.; Wilson, G. A.; Jamal-Hanjani, M.; Swanton, C.; TRACERx Consortium, ; McGranahan, N.

10.1101/513457 — genomics — Posted on 2019-01-07

2600 Diversity patterns in parasite populations capable forpersistence and reinfection

Pokalyuk, C.; Goerzer, I.

10.1101/512970 — evolutionary biology — Posted on 2019-01-07

2601 A Reaction Norm Perspective on Reproducibility

Voelkl, B.; Würbel, H.

10.1101/510941 — developmental biology — Posted on 2019-01-07

2602 Visual-olfactory integration in the human disease vector mosquito, Aedes aegypti

Vinauger, C.; Van Breugel, F.; Locke, L.; Tobin, K.; Dickinson, M.; Fairhall, A.; Akbari, O.; Riffell, J.

10.1101/512996 — neuroscience — Posted on 2019-01-07

2603 NOTCH assembles a transcriptional repressive complex containing NuRD and PRC1 to repress genes involved in cell proliferation and differentiation.

Doyen, C. M.; Depierre, D.; Yatim, A.; Heurteau, A.; Lelievre, J. D.; Levy, Y.; Cuvier, O.; Benkirane, M.

10.1101/513549 — molecular biology — Posted on 2019-01-07

2604 Genomic analyses of sibling honey bee ectoparasitic mite species show divergent strategies of adaptation

Techer, M. A.; Rane, R. V.; Grau, M. L.; Roberts, J. M. K.; Sullivan, S. T.; Liachko, I.; Childers, A. K.; Evans, J. D.; Mikheyev, A. S.

10.1101/512988 — genomics — Posted on 2019-01-07

2605 Mülleriann mimicry in bumble bees is a transient continuum

Ezray, B. D.; Wham, D. C.; Hill, C.; Hines, H. M.

10.1101/513275 — evolutionary biology — Posted on 2019-01-07

2606 Indolergic receptors of the elephant mosquito Toxorhynchites amboinensis

Dekel, A.; Yakir, E.; Bohbot, J.

10.1101/513044 — evolutionary biology — Posted on 2019-01-07

2607 Glycosylphosphatidylinositol Biosynthesis and Remodeling are Required for Neural Crest Cell, Cardiac and Neural Development.

Lukacs, M.; Roberts, T.; Chaturvedi, P.; Stottmann, R.

10.1101/513507 — developmental biology — Posted on 2019-01-07

2608 CHCHD4 regulates a proliferation-EMT switch in tumour cells, through respiratory complex I mediated metabolism.

Thomas, L. W.; Esposito, C.; Stephen, J. M.; Costa, A. S.; Frezza, C.; Blacker, T. S.; Szabadkai, G.; Ashcroft, M.

10.1101/513531 — cell biology — Posted on 2019-01-07

2609 Buckling of epithelium growing under spherical confinement

Trushko, A.; Di Meglio, I.; Merzouki, A.; Blanch-Mercader, C.; Abuhattum, S.; Guck, J.; Alessandri, K.; Nassoy, P.; Kruse, K.; Chopard, B.; Roux, A.

10.1101/513119 — biophysics — Posted on 2019-01-07

2610 Detecting convergent adaptive amino acid evolution

Rey, C.; Lanore, V.; Veber, P.; Gueguen, L.; Lartillot, N.; Semon, M.; Boussau, B.

10.1101/513010 — bioinformatics — Posted on 2019-01-07

2611 ELECTOR: Evaluator for long reads correction methods

Marchet, C.; Morisse, P.; Lecompte, L.; Limasset, A.; Lefebvre, A.; Lecroq, T.; Peterlongo, P.

10.1101/512889 — bioinformatics — Posted on 2019-01-07

2612 Evaluation of liver protective activity of Moringa oleifera bark extract in paracetamol induced hepatotoxicity in rats.

Islam, R.; Alam, M. J.

10.1101/513002 — pharmacology and toxicology — Posted on 2019-01-07

2613 Computing Hubs in the Hippocampus and Cortex

Clawson, W. P.; Vicente, A. F.; Bernard, C.; Battaglia, D.; Quilichini, P. P.

10.1101/513424 — neuroscience — Posted on 2019-01-07

2614 A Preliminary Occurrence of Extended-Spectrum and AmpC Beta-Lactamases in Clinical Isolates of Enteropathogenic Escherichia coli in Najaf, Iraq

Alsherees, H. A.; Ali, S. N. A.

10.1101/512731 — microbiology — Posted on 2019-01-07

2615 Time- and size-resolved bacterial aerosol dynamics in highly polluted air: new clues for haze formation mechanism

Zhang, T.; Li, X.; Wang, M.; Chen, H.; Yao, M.

10.1101/513093 — microbiology — Posted on 2019-01-07

2616 Integrated multi-omics analysis to study the effects of simulated weightlessness on rhesus macaques (Macaca mulatta)

Peng, Z.; Libin, S.; Jie, Z.; Wenjiong, L.; Guangyi, F.; Ying, Z.; Guanghan, K.; Hongju, L.; Weidong, L.; Fei, W.; Xixia, C.; Peng, H.; Ling, P.; Xingmin, L.; Jianwei, C.; Xinming, L.; Jingkai, J.; Shiyi, D.; Zhanlong, M.; Ronghui, L.; Xun, X.; Shanguang, C.; Xin, L.; Xiaoping, C.

10.1101/513382 — immunology — Posted on 2019-01-07

2617 Characterization of a novel vascular bundle localizing Gossypium hirsutum NAC4 transcription factor promoter for its role in environmental stress responses

Shalibhadra Vikas, T.; Marriboina, S.; Boyidi, P.; Gudipalli, P.; Kirti, P.

10.1101/510578 — plant biology — Posted on 2019-01-07

2618 Inhibition of miR-22-3p reduces kidney disease associated with systemic lupus erythematosus

Michell, D. L.; Faust, A.; Moore, J. L.; Appleton, B. D.; Ormseth, M.; Ramirez-Solano, M.; Sheng, Q.; Solus, J. F.; Stein, C. M.; Vickers, K. C.; Major, A. S.

10.1101/512848 — immunology — Posted on 2019-01-07

2619 Can Sexual Selection Cause Divergence In Mating System-Related Floral Traits?

Lankinen, A.; Strandh, M.

10.1101/513481 — evolutionary biology — Posted on 2019-01-07

2620 Range-wide variation in local adaptation and phenotypic plasticity of fitness-related traits in Fagus sylvatica and their implications under climate change

Garate-Escamilla, H.; Hampe, A.; Vizcaino-Palomar, N.; Robson, M.; Benito Garzon, M.

10.1101/513515 — ecology — Posted on 2019-01-07

2621 Minimal membrane interactions conferred by Rheb C-terminal farnesylation are essential for mTORC1 activation

Ferguson, S. M.; Angarola, B.

10.1101/513473 — cell biology — Posted on 2019-01-07

2622 Neural circuitry of dialects through social learning in Drosophila.

Kacsoh, B. Z.; Bozler, J.; Hodge, S.; Bosco, G.

10.1101/511857 — neuroscience — Posted on 2019-01-07

2623 Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types

Nadadur, R. D.; Perez-Cervantes, C.; Lonfat, N.; Smith, L. A.; Hughes, A. E. O.; Wang, S.; Corbo, J. C.; Cepko, C. L.; Moskowitz, I. P.

10.1101/513598 — molecular biology — Posted on 2019-01-07

2624 High concentration and yield production of mannose from acai (Euterpe oleracea) seeds via diluted-acid and mannanase-catalyzed hydrolysis

Ferreira Monteiro, A.; Santos Miguez, I.; Pedro Rodrigues Barros Silva, J.; Santana Silva, A.

10.1101/513168 — biochemistry — Posted on 2019-01-07

2625 Apollo: Democratizing genome annotation

Dunn, N.; Unni, D.; Diesh, C.; Munoz-Torres, M.; Harris, N.; Yao, E.; Rasche, H.; Holmes, I.; Elsik, C.; Lewis, S.

10.1101/512376 — bioinformatics — Posted on 2019-01-06

2626 Benchmarking Time-Series Data Discretization on Inference Methods

Li, Y.; Jann, T.; Vera-Licona, P.

10.1101/378620 — systems biology — Posted on 2019-01-06

2627 Multilocus sequence analysis, a rapid and accurate identification tool for taxonomic classification, evolutionary relationship and population biology of the genus Shewanella.

Fang, Y.; Wang, Y.; Liu, Z.; Dai, H.; Cai, H.; Li, Z.; Du, Z.; Wang, X.; Jing, H.; Wei, Q.; Kan, B.; Wang, D.

10.1101/512624 — microbiology — Posted on 2019-01-06

2628 Role of the Campylobacter jejuni cheVAWY chemotaxis genes in chemotactic motility and biofilm formation

Reuter, M.; Ultee, E.; toseafa, Y.; Tan, A.; van Vliet, A. H. M.

10.1101/449850 — microbiology — Posted on 2019-01-06

2629 Estimating residence times of lymphocytes in ovine lymph nodes

McDaniel, M. M.; Ganusov, V.

10.1101/513176 — immunology — Posted on 2019-01-06

2630 Splicing inhibition enhances the antitumor immune response through increased tumor antigen presentation and altered MHC-I immunopeptidome

Pierson, A.; Darrigrand, R.; Rouillon, M.; Boulpicante, M.; Renko, Z. D.; Garcia, C.; Ghosh, M.; Laiguillon, M.-C.; Lobry, C.; Alami, M.; Apcher, S.

10.1101/512681 — immunology — Posted on 2019-01-06

2631 Protein Co-Evolution Strategies Detect Predicted Functional Interaction Between the Serotonin 5-HT2A and 5-HT2C Receptors

Fongang, B.; Cunningham, K. A.; Rowicka, M.; Kudlicki, A.

10.1101/512558 — neuroscience — Posted on 2019-01-06

2632 All-optical interrogation of a direction selective retinal circuit by holographic wave front shaping

Spampinato, G. L. B.; Ronzitti, E.; Zampini, V.; Ferrari, U.; Trapani, F.; Khabou, H.; Dalkara, D.; Picaud, S.; Papagiakoumou, E.; Marre, O.; Emiliani, V.

10.1101/513192 — neuroscience — Posted on 2019-01-06

2633 A ribosome assembly stress response regulates transcription to maintain proteome homeostasis

Albert, B.; Kos-Braun, I. C.; Henras, A. K.; Dez, C.; Rueda, M. P.; Zhang, X.; Gadal, O.; Kos, M.; Shore, D.

10.1101/512665 — molecular biology — Posted on 2019-01-06

2634 The Largest Subunit of Human TFIIIC Complex, TFIIIC220, a Lysine Acetyltransferase Targets Histone H3K18

Basu, M.; Boopathi, R.; Das, S.; Kundu, T. K.

10.1101/513127 — molecular biology — Posted on 2019-01-06

2635 Budding yeast centromeric DNA and A+T rich bacterial DNA can function as centromeres in the fission yeast Schizosaccharomyces pombe.

Barbosa, A. C.; Xu, Z.; Karari, K.; Hauf, S.; Brown, W. R.

10.1101/513150 — genetics — Posted on 2019-01-06

2636 scSVA: an interactive tool for big data visualization and exploration in single-cell omics

Tabaka, M.; Gould, J.; Regev, A.

10.1101/512582 — bioinformatics — Posted on 2019-01-06

2637 Tumors escape immunosurveillance by overexpressing the proteasome activator REGγ

Boulpicante, M.; Darrigrand, R.; Pierson, A.; Salgues, V.; Gaudineau, B.; Khaled, M.; Cattaneo, A.; Bachi, A.; Cascio, P.; Apcher, S.

10.1101/511873 — immunology — Posted on 2019-01-06

2638 Colonial ascidians strongly preyed upon, yet dominate the substrate in a subtropical fouling community

Hiebert, L. S.; Vieira, E. A.; Dias, G. M.; Tiozzo, S.; Brown, F. D.

10.1101/512699 — ecology — Posted on 2019-01-06

2639 Evaluation of self-generated behavior: untangling metacognitive read-out and error-detection.

Kononowicz, T.; van Wassenhove, V.

10.1101/513242 — neuroscience — Posted on 2019-01-06

2640 The Proteome of Tetrasphaera elongata is Prepadapted to Changing Environmental Conditions in Wastewater Treatment Plants

Herbst, F.-A.; Dueholm, M. S.; Wimmer, R.; Nielsen, P. H.

10.1101/513143 — microbiology — Posted on 2019-01-06

2641 The gut microbiota is associated with clearance of Clostridium difficile infection independent of adaptive immunity

Leslie, J. L.; Vendrov, K. C.; Jenior, M. L.; Young, V. B.

10.1101/512616 — microbiology — Posted on 2019-01-06

2642 In Silico Screening and Analysis of SNPs in Human ABCB1 (MDR1) Gene

Hussien, A.; Osman, A. A. M.

10.1101/505859 — bioinformatics — Posted on 2019-01-06

2643 Split sex-ratio and variability in aggressive behavior in desert ants

Inbar, S.; Privman, E.

10.1101/478552 — evolutionary biology — Posted on 2019-01-06

2644 Disassembly of actin and keratin networks by Aurora B kinase at the midplane of cleaving Xenopus laevis eggs

Field, C. M.; Pelletier, J. F.; Mitchison, T.

10.1101/513200 — cell biology — Posted on 2019-01-06

2645 More than a flying syringe: Using functional traits in vector borne disease research

Cator, L.; Johnson, L. R.; Mordecai, E. A.; El Moustaid, F.; Smallwood, T.; La Deau, S.; Johansson, M.; Hudson, P. J.; Boots, M.; Thomas, M. B.; Power, A. G.; Pawar, S.

10.1101/501320 — ecology — Posted on 2019-01-06

2646 GToTree: a user-friendly workflow for phylogenomics

Lee, M. D.

10.1101/512491 — bioinformatics — Posted on 2019-01-06

2647 Analysis of >30,000 abstracts suggests higher false discovery rates for oncology journals, especially those with low impact factors

Hall, L. M.; Hendricks, A. E.

10.1101/500660 — scientific communication and education — Posted on 2019-01-06

2648 Comparative study of population genomic approaches for mapping colony-level traits

Inbar, S.; Cohen, P.; Yahav, T.; Privman, E.

10.1101/479600 — bioinformatics — Posted on 2019-01-06

2649 Microtubule plus-end dynamics link wound repair to the innate immune response

Taffoni, C.; Omi, S.; Huber, C.; Mailfert, S.; Fallet, M.; Ewbank, J.; Pujol, N.

10.1101/512632 — cell biology — Posted on 2019-01-06

2650 Cdc42 promotes epithelial morphogenesis by coupling Par-complex and Crumbs recruitment via Par6-aPKC

Nunes De Almeida, F.; Walther, R. F.; Presse, M. T.; Vlassaks, E.; Pichaud, F.

10.1101/513028 — cell biology — Posted on 2019-01-06

2651 Longitudinal single cell profiling of regulatory T cells identifies IL-33 as a driver of tumor immunosuppression

Li, A.; Herbst, R. H.; Canner, D.; Schenkel, J. M.; Smith, O. C.; Kim, J. Y.; Hillman, M.; Bhutkar, A.; Cuoco, M. S.; Rappazzo, C. G.; Rogers, P.; Dang, C. Q.; Rozenblatt-Rosen, O.; Cong, L.; Birnbaum, M.; Regev, A.; Jacks, T.

10.1101/512905 — cancer biology — Posted on 2019-01-06

2652 Rigorous equations for isothermal titration calorimetry: theoretical and practical consequences

Dumas, P.

10.1101/512780 — biophysics — Posted on 2019-01-06

2653 The landscape of DNA methylation associated with the transcriptomic network in laying hens and broilers generates insight into embryonic muscle development in chicken

Liu, Z.; Shen, X.; Han, S.; Wang, Y.; Zhu, Q.; Cui, C.; He, H.; Zhao, J.; Chen, Y.; Zhang, Y.; Ye, L.; Zhang, Z.; Liu, D.; Zhao, X.; Yin, H.

10.1101/470278 — bioinformatics — Posted on 2019-01-06

2654 Hypoxia induces rapid changes to histone methylation reprogramming chromatin for the cellular response

Batie, M.; Frost, J.; Frost, M.; Wilson, J. W.; Schofield, P.; Rocha, S.

10.1101/513069 — biochemistry — Posted on 2019-01-06

2655 A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish.

Kardash, E.; Nguyen, H.; Behrndt, M.; Heisenberg, C.-P.; Peyrieras, N.; Gonzalez-Gaitan, M.

10.1101/512038 — developmental biology — Posted on 2019-01-06

2656 Evolutionary loss of foot muscle during development with characteristics of atrophy and no evidence of cell death

Tran, M. P.; Tsutsumi, R.; Erberich, J. M.; Chen, K. D.; Flores, M. D.; Cooper, K. L.

10.1101/512590 — developmental biology — Posted on 2019-01-06

2657 DO-MS: Data-Driven Optimization of Mass Spectrometry Methods

Huffman, G.; Specht, H.; Chen, A. T.; Slavov, N.

10.1101/512152 — bioinformatics — Posted on 2019-01-06

2658 Fundamental Law of Memory Recall

Naim, M.; Katkov, M.; Tsodyks, M.

10.1101/510750 — neuroscience — Posted on 2019-01-06

2659 Active cargo positioning in antiparallel transport networks

Richard, M.; Blanch-Mercader, C.; Ennomani, H.; Cao, W.; De La Cruz, E.; Joanny, J.-F.; Jülicher, F.; Blanchoin, L.; Martin, P.

10.1101/512863 — biophysics — Posted on 2019-01-06

2660 The Generalized Data Model for Clinical Research

Danese, M. D.; Halperin, M.; Duryea, J.; Duryea, R.

10.1101/194597 — bioinformatics — Posted on 2019-01-05

2661 Experimentally-constrained biophysical models of tonic and burst firing modes in thalamocortical neurons

Iavarone, E.; Yi, J.; Shi, Y.; Zandt, B.-J.; O'Reilly, C.; Van Geit, W.; Rössert, C.; Markram, H.; Hill, S. L.

10.1101/512269 — neuroscience — Posted on 2019-01-05

2662 MATRIEX Imaging: Multi-Area Two-photon Real-time In-vivo Explorer

Yang, M.; Zhou, Z.; Zhang, J.; Li, T.; Guan, J.; Liao, X.; Leng, B.; Lyu, J.; Yan, J.; Zhang, K.; Gong, Y.; Tang, Y.; Zhu, Z.; Varga, Z.; Konnerth, A.; Gao, J.; Chen, X.; Jia, H.

10.1101/510545 — neuroscience — Posted on 2019-01-05

2663 Mental simulation of facial expressions: Mu suppression to the viewing of dynamic neutral face videos

Karakale, O.; Moore, M. R.; Kirk, I. J.

10.1101/457846 — neuroscience — Posted on 2019-01-05

2664 Nanoscale mapping of DNA dynamics in live human cells

Shaban, H. A.; Barth, R.; Bystricky, K.

10.1101/405969 — biophysics — Posted on 2019-01-05

2665 Sterile spikelets assimilate carbon in sorghum and related grasses

AuBuchon-Elder, T.; Coneva, V.; Goad, D. M.; Allen, D. K.; Kellogg., E. A.

10.1101/396473 — plant biology — Posted on 2019-01-05

2666 A Novel Animal Model Of Somatosensory-Evoked Reflex Seizures Induced By Peripheral Stimulation

Bortel, A.; Pilgram, R.; Yao, Z. S.; Shmuel, A.

10.1101/506352 — neuroscience — Posted on 2019-01-05

2667 Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction.

Sigalova, O.; Chaplin, A. V.; Bochkareva, O. O.; Shelyakin, P. V.; Filaretov, V. A.; Akkuratov, E. E.; Burskaya, V.; Gelfand, M. S.

10.1101/506121 — genomics — Posted on 2019-01-05

2668 The complete structure of the human TFIIH core complex

Greber, B.; Toso, D.; Fang, J.; Nogales, E.

10.1101/507723 — biophysics — Posted on 2019-01-05

2669 GToTree: a user-friendly workflow for phylogenomics

Lee, M. D.

10.1101/512491 — bioinformatics — Posted on 2019-01-05

2670 A novel core genome approach to enable prospective and dynamic monitoring of infectious outbreaks

van Aggelen, H.; Kolde, R.; Chamarthi, H.; Loving, J.; Fan, Y.; Fallon, J. T.; Huang, W.; Wang, G.; Fortunato-Habib, M. M.; Carmona, J. J.; Gross, B. D.

10.1101/421388 — bioinformatics — Posted on 2019-01-05

2671 Sensitive periods for white matter plasticity and reading intervention

Yeatman, J. D.; Huber, E.

10.1101/346759 — neuroscience — Posted on 2019-01-05

2672 LTP induction drives remodeling of astroglia to boost glutamate escape from synapses

Henneberger, C.; Bard, L.; Panatier, A.; Reynolds, J. P.; Medvedev, N. I.; Minge, D.; Herde, M. K.; Anders, S.; Kraev, I.; Heller, J.; Kopach, O.; Rama, S.; Zheng, K.; Jensen, T. P.; Sanchez-Romero, I.; Janovjak, H.; Ottersen, O.-P.; Nagelhus, E.-A.; Oliet, S. H. R.; Stewart, M. G.; Nagerl, U. V.; Rusakov, D. A.

10.1101/349233 — neuroscience — Posted on 2019-01-05

2673 Moments reconstruction and local dynamic range compression of high order Superresolution Optical Fluctuation Imaging

Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S.

10.1101/500819 — bioengineering — Posted on 2019-01-05

2674 GToTree: a user-friendly workflow for phylogenomics

Lee, M. D.

10.1101/512491 — bioinformatics — Posted on 2019-01-05

2675 Intracellular delivery of mRNA to human primary T cells with microfluidic vortex shedding

Jarrell, J. A.; Twite, A. A.; Lau, K. H. W. J.; Kashani, M. N.; Lievano, A. A.; Acevedo, J.; Priest, C.; Nieva, J.; Gottlieb, D.; Pawell, R. S.

10.1101/343426 — bioengineering — Posted on 2019-01-05

2676 Classical conditioning in oddball paradigm: A comparison between aversive and name conditioning

Pavlov, Y. G.; Kotchoubey, B.

10.1101/286492 — neuroscience — Posted on 2019-01-05

2677 Transcranial direct current stimulation (tDCS) over the left prefrontal cortex does not affect time-trial self-paced cycling performance: Evidence from oscillatory brain activity and power output.

Holgado, D.; Zandonai, T.; Ciria, L. F.; Zabala, M.; Hopker, J.; Sanabria, D.

10.1101/341388 — neuroscience — Posted on 2019-01-05

2678 Cluster Tendency Assessment in Neuronal Spike Data

Mahallati, S.; Bezdek, J. C.; Popovic, M. R.; Valiante, T. A.

10.1101/285064 — neuroscience — Posted on 2019-01-05

2679 Drug target identification and virtual screening in pursuit of phytochemical intervention of Mycobacterium chelonae

Basharat, Z.; Zaib, S.; Yasmin, A.; Tong, Y.

10.1101/315408 — bioinformatics — Posted on 2019-01-05

2680 Defecation by the ctenophore Mnemiopsis leidyi occurs with an ultradian rhythm through a single transient anal pore

Tamm, S.

10.1101/511576 — zoology — Posted on 2019-01-05

2681 Genetic risk for major depressive disorder and loneliness in gender-specific associations with coronary artery disease

Dennis, J.; Sealock, J.; Levinson, R. T.; Farber-Eger, E.; Franco, J.; Fong, S.; Straub, P.; Hucks, D.; Linton, M. F.; Song, W.-L.; Fontanillas, P.; Elson, S. L.; Ruderfer, D.; Abdellaoui, A.; Sanchez-Roige, S.; Palmer, A. A.; Boomsma, D. I.; Cox, N.; Chen, G.; Mosley, J. D.; Wells, Q. S.; Davis, L.

10.1101/512541 — genetics — Posted on 2019-01-05

2682 Probing cellular response to topography in three dimensions

Paul, C. D.; Hruska, A.; Staunton, J. R.; Burr, H. A.; Daly, K. M.; Kim, J.; Jiang, N.; Tanner, K.

10.1101/232066 — bioengineering — Posted on 2019-01-05

2683 Identification of Factors Complicating Bioluminescence Imaging

Yeh, H.-W.; Wu, T.; Chen, M.; Ai, H.

10.1101/511501 — biochemistry — Posted on 2019-01-04

2684 Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure

Stone, N.; Demo, G.; Agnello, E.; Kelch, B. A.

10.1101/473264 — biochemistry — Posted on 2019-01-05

2685 Experimentally-constrained biophysical models of tonic and burst firing modes in thalamocortical neurons

Iavarone, E.; Yi, J.; Shi, Y.; Zandt, B.-J.; O'Reilly, C.; Van Geit, W.; Rössert, C.; Markram, H.; Hill, S. L. L.

10.1101/512269 — neuroscience — Posted on 2019-01-04

2686 Diffeomorphic registration with intensity transformation and missing data: Application to 3D digital pathology of Alzheimer’s disease

Tward, D. J.; Brown, T.; Kageyama, Y.; Patel, J.; Hou, Z.; Mori, S.; Albert, M.; Troncoso, J.; Miller, M.

10.1101/494005 — neuroscience — Posted on 2019-01-04

2687 Evolutionary implications of the microRNA- and piRNA complement of Lepidodermella squamata (Gastrotricha)

Fromm, B.; Tosar, J. P.; Aguilera, F.; Friedlander, M. R.; Bachmann, L.; Hejnol, A.

10.1101/504100 — evolutionary biology — Posted on 2019-01-04

2688 Discovery of New Classes of Glycine transporter 2 (GlyT2) Inhibitors and Study of GlyT2 Selectivity by Combination of Novel Structural Based Virtual Screening Approach and Free Energy Perturbation (FEP+) Calculations

Fratev, F.; Miranda-Arango, M.; Padilla, E.; Sirimulla, S.

10.1101/510487 — biophysics — Posted on 2019-01-04

2689 Specific inflammatory and mitochondrial signatures characterise the WSB/EiJ mice diet-induced obesity resistance capacity

Terrien, J.; Seugnet, I.; Seffou, B.; Herrero, M. J.; Bowers, J.; Chamas, L.; Decherf, S.; Duvernois-Berthet, E.; Djediat, C.; Ducos, B.; Demeneix, B. A.; Clerget-Froidevaux, M.-S.

10.1101/504308 — physiology — Posted on 2019-01-04

2690 Assessment of Environmental and Occupational Exposure while Working with Candida auris a Multidrug Resistant (MDR) Fungus in the Animal Facility.

Torres, S. R.; Kim, H. C.; Leach, L.; Chaturvedi, S.; Bennett, C. J.; Hill, D. J.; De Jesus, M.

10.1101/486100 — microbiology — Posted on 2019-01-04

2691 Plate-based assay of AP-3 traffic in budding yeast

Plemel, R. L.; Odorizzi, G.; Merz, A. J.

10.1101/314286 — cell biology — Posted on 2019-01-04

2692 Repeated assessment of anxiety-like behavior in mice: a new tool with increased reliability and consistency.

PREVOT, T. D.; Misquitta, K. A.; Fee, C.; Newton, D.; Chatterjee, D.; Nikolova, Y. S.; Sibille, E.; Banasr, M.

10.1101/414029 — animal behavior and cognition — Posted on 2019-01-04

2693 Apollo: Democratizing genome annotation

Dunn, N.; Unni, D.; Munoz-Torres, M.; Munoz-Torres, M.; Harris, N.; Yao, E.; Rasche, H.; Holmes, I.; Elsik, C.; Lewis, S.

10.1101/512376 — bioinformatics — Posted on 2019-01-04

2694 The Role of the Wnt/PCP Formin Daam1 in Renal Ciliogenesis

Corkins, M. E.; Krneta-Stankic, V.; Kloc, M.; McCrea, P. D.; Gladden, A. B.; Miller, R. K.

10.1101/512533 — molecular biology — Posted on 2019-01-04

2695 The future of a partially effective HIV vaccine: assessing limitations at the population level

Selinger, C.; Dimitroff, D. T.; Welkhoff, P.; Bershteyn, A.

10.1101/509828 — epidemiology — Posted on 2019-01-04

2696 Patterns of Treatment in Patients with Heart Failure with Preserved Ejection Fraction: the REasons for Geographic And Racial Differences in Stroke study

Poudel, B.; Loop, M. S.; Brown, T. M.; Durant, R. W.; Safford, M. M.; Goyal, P.; Chen, L.; Levitan, E. B.

10.1101/510370 — epidemiology — Posted on 2019-01-04

2697 Community-level impacts of spatial repellents for control of diseases vectored by Aedes aegypti mosquitoes

ten Bosch, Q. A.; Wagman, J. M.; Castro-Llanos, F.; Achee, N. L.; Grieco, J. P.; Perkins, A. T.

10.1101/501700 — epidemiology — Posted on 2019-01-04

2698 Specific domains of early parenting, their heritability and differential association with adolescent behavioural and emotional disorders and academic achievement

Culpin, I.; Bornstein, M. H.; Putnick, D. L.; Sallis, H.; Lee, R.; Cordero, M.; Rajyaguru, P.; Kordas, K.; Cadman, T.; Pearson, R. M.

10.1101/509513 — epidemiology — Posted on 2019-01-04

2699 Comprehensive mapping of avian influenza polymerase adaptation to the human host

Soh, Y. Q. S.; Moncla, L. H.; Eguia, R.; Bedford, T.; Bloom, J. D.

10.1101/512525 — microbiology — Posted on 2019-01-04

2700 Harmonisation of Physical Activity Variables by Indirect Validation: A Doubly Labelled Water Study

Pearce, M.; Bishop, T. R.; Sharp, S.; Westgate, K.; Venables, M.; Wareham, N. J.; Brage, S.

10.1101/501718 — epidemiology — Posted on 2019-01-04

2701 Rise in mortality involving poisoning by medicaments other than narcotics, including poisoning by psychotropic and sedative-hypnotic drugs in different age/racial groups in the US

Goldstein, E.

10.1101/509729 — epidemiology — Posted on 2019-01-04

2702 Effects of Curative-Intent Lung Cancer Therapy on Functional Exercise Capacity and Patient-Reported Outcomes

Ha, D.; Ries, A. L.; Lippman, S. M.; Fuster, M. M.

10.1101/508234 — epidemiology — Posted on 2019-01-04

2703 Effects of altering histone post-translational modifications on mitotic chromosome structure and mechanics

Biggs, R.; Stephens, A. D.; Liu, P.; Marko, J. F.

10.1101/423541 — cell biology — Posted on 2019-01-04

2704 Comparative analysis of epigenetic aging clocks from CpG characteristics to functional associations

Liu, Z.; Leung, D.; Levine, M.

10.1101/512483 — bioinformatics — Posted on 2019-01-04

2705 Social touch observation in adults with autism: intact neural representations of affective meaning but lack of embodied resonance

Lee Masson, H.; Pillet, I.; Amelynck, S.; Van De Plas, S.; Hendriks, M.; Op de Beeck, H.; Boets, B.

10.1101/512327 — neuroscience — Posted on 2019-01-04

2706 Pseudomonas aeruginosa Can Inhibit Growth of Streptococcal Species via Siderophore Production

Scott, J.; Li, K.; Filkins, L.; Zhu, B.; Kuchma, S.; Schwartzman, J.; O'Toole, G.

10.1101/307488 — microbiology — Posted on 2019-01-04

2707 MATRIEX Imaging: Multi-Area Two-photon Real-time In-vivo Explorer

Jia, H.; Yang, M.; Zhou, Z.; Zhang, J.; Li, T.; Guan, J.; Liao, X.; Leng, B.; Lyu, J.; Yan, J.; Zhang, K.; Gong, Y.; Tang, Y.; Zhu, Z.; Varga, Z.; Konnerth, A.; Gao, J.; Chen, X.

10.1101/510545 — neuroscience — Posted on 2019-01-04

2708 The Trouble Interpreting fMRI Studies in Populations with Cerebrovascular Risk: The Use of a Subject-Specific Hemodynamic Response Function in a Study of Age, Vascular Risk, and Memory

McDonough, I. M.; Bender, A.; Patihis, L.; Stinson, E. A.; Letang, S. K.; Miller, W. S.

10.1101/512343 — neuroscience — Posted on 2019-01-04

2709 Ecological causes of uneven diversification and richness in the mammal tree of life

Upham, N.; Esselstyn, J. A.; Jetz, W.

10.1101/504803 — evolutionary biology — Posted on 2019-01-04

2710 iTALK: an R Package to Characterize and Illustrate Intercellular Communication

Wang, Y.; Wang, R.; Zhang, S.; Song, S.; Jiang, C.; Han, G.; Wang, M.; Ajani, J.; Futreal, A.; Wang, L.

10.1101/507871 — cancer biology — Posted on 2019-01-04

2711 The Replication-Competent HIV-1 Latent Reservoir is Primarily Established Near the Time of Therapy Initiation

Abrahams, M.-R.; Joseph, S. B.; Garrett, N.; Tyers, L.; Moeser, M.; Archin, N.; Council, O. D.; Matten, D.; Zhou, S.; Doolabh, D.; Anthony, C.; Goonetilleke, N.; Karim, S. A.; Margolis, D. M.; Kosakovsky Pond, S.; Williamson, C.; Swanstrom, R.

10.1101/512475 — microbiology — Posted on 2019-01-04

2712 Influenza A virus surface proteins are organized to help penetrate host mucus

Vahey, M. D.; Fletcher, D. A.

10.1101/512467 — microbiology — Posted on 2019-01-04

2713 Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of FSHD

Jagannathan, S.; Ogata, Y.; Gafken, P.; Tapscott, S. J.; Bradley, R. K.

10.1101/417790 — genomics — Posted on 2019-01-04

2714 Kinome-wide activity classification of small molecules by deep learning

Allen, B. K.; Ayad, N. G.; Schürer, S. C.

10.1101/512459 — pharmacology and toxicology — Posted on 2019-01-04

2715 The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation

Zhang, M.; Wang, B.; Urabe, G.; Huang, Y.; Plutzky, J.; Kent, K. C.; Guo, L.-W.

10.1101/509414 — pathology — Posted on 2019-01-04

2716 Next Generation-Targeted Amplicon Sequencing (NG-TAS): An optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA

Gao, M.; Callari, M.; Beddowes, E.; Sammut, S.-J.; Grzelak, M.; Biggs, H.; Jones, L.; Boumertit, A.; Linn, S. C.; Cortes, J.; Oliveira, M.; Baird, R.; Chin, S.-F.; Caldas, C.

10.1101/366534 — genomics — Posted on 2019-01-04

2717 A pitfall for machine learning methods aiming to predict across cell types

Schreiber, J.; Singh, R.; Bilmes, J.; Noble, W. S.

10.1101/512434 — bioinformatics — Posted on 2019-01-04

2718 Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance

Maltas, J.; Wood, K. B.

10.1101/241075 — evolutionary biology — Posted on 2019-01-04

2719 The MHC class-II HLA-DR receptor mediates bat influenza A-like H17N10 virus entry into mammalian cells

Giotis, E. S.; Carnell, G.; Young, E. F.; Ghanny, S.; Soteropoulos, P.; Barclay, W. S.; Skinner, M. A.; Temperton, N.

10.1101/507467 — microbiology — Posted on 2019-01-04

2720 REC8-cohesin, chromatin and transcription orchestrate meiotic recombination in the Arabidopsis genome

Lambing, C.; Tock, A. J.; Choi, K.; Topp, S. D.; Kuo, P. C.; Blackwell, A. R.; Zhao, X.; Osman, K.; Higgins, J. D.; Franklin, F. C. H.; Henderson, I. R.

10.1101/512400 — genomics — Posted on 2019-01-04

2721 TMEM98 is a negative regulator of FRAT mediated Wnt/β-catenin signalling

van der Wal, T.; Lambooij, J.-P.; Wiese, K. E.; van Amerongen, R.

10.1101/512426 — cell biology — Posted on 2019-01-04

2722 Kinetics of enzymatic mercury methylation at nanomolar concentrations catalyzed by HgcAB

Date, S. S.; Parks, J. M.; Rush, K. W.; Wall, J. D.; Ragsdale, S. W.; Johs, A.

10.1101/510180 — biochemistry — Posted on 2019-01-04

2723 Tombusvirus p19 captures RNase III-cleaved double-stranded RNAs formed by overlapping sense and antisense transcripts in E. coli

Huang, L.; Deighan, P.; Jin, J.; Li, Y.; Lee, E.; Mo, S. S.; Hoover, H.; Abubucker, S.; Finkel, N.; McReynolds, L.; Hochschild, A.; Lieberman, J.

10.1101/510842 — microbiology — Posted on 2019-01-04

2724 Statistics of chromatin organization during cell differentiation revealed by heterogeneous cross-linked polymers

Shukron, O.; Piras, V.; Noordermeer, D.; Holcman, D.

10.1101/235051 — genomics — Posted on 2019-01-04

2725 Population-based Relative Risks for Specific Family History Constellations of Breast Cancer

Albright, F. S.; Kohlmann, W.; Neumayer, L.; Buys, S. S.; Matsen, C. B.; Kaphingst, K. A.; Cannon-Albright, L. A.

10.1101/136051 — genetics — Posted on 2019-01-04

2726 Helpers increase daily survival rate of Southern Lapwing (Vanellus chilensis) nests during the incubation stage

Santos, E. S. A.; Macedo, R. H.

10.1101/179606 — animal behavior and cognition — Posted on 2019-01-04

2727 Individual listening success explained by synergistic interaction of two distinct neural filters

Tune, S.; Fiedler, L.; Alavash, M.; Obleser, J.

10.1101/512251 — neuroscience — Posted on 2019-01-04

2728 Adolescent forced swim stress increases social anxiety-like behaviors and alters the dynorphin/kappa opioid receptor system in the basolateral amygdala of males

Varlinskaya, E. I.; Johnson, J. M.; Deak, T.; Diaz, M. R.

10.1101/512350 — neuroscience — Posted on 2019-01-04

2729 Genetic structure and sodium channel gene mutation analysis related to pyrethroid insecticide toxicity in sylvatic Andean Triatoma infestans from Bolivia

Marcet, P. L.; Santo-Orihuela, P.; Messenger, L. A.; Vassena, C. V.

10.1101/512392 — genetics — Posted on 2019-01-04

2730 Automation for the identification of Pseudomonas aeruginosa: Comparison of TDR-300B, VITEK(R)2, and VITEK(R)-MS

Moehario, L. H.; Boestami, H. P.; Edbert, D.; Tjoa, E.; Robertus, T.

10.1101/510107 — microbiology — Posted on 2019-01-04

2731 Genetic dissection of femoral and tibial microarchitecture

Lu, L.; Huang, J.; Xu, F.; Xiao, Z.; Wang, J.; Zhang, B.; David, N. V.; Arends, D.; Gu, W.; Ackert-Bicknell, C.; Sabik, O. L.; Farber, C. R.; Quarles, L. D.; Williams, R. W.

10.1101/512103 — genetics — Posted on 2019-01-04

2732 Crossing fitness valleys via double substitutions within codons

Belinky, F.; Sela, I.; Rogozin, I. B.; Koonin, E. V.

10.1101/511469 — evolutionary biology — Posted on 2019-01-04

2733 Blanding’s turtles (Emydoidea blandingii) as a reservoir for Leptospira spp

Rockwell, K. E.; Thompson, D.; Maddox, C.; Mitchell, M. A.

10.1101/510149 — epidemiology — Posted on 2019-01-04

2734 Integrative Computational Framework for Understanding Metabolic Modulation in Leishmania

Chauhan, N.; Singh, S.

10.1101/512277 — systems biology — Posted on 2019-01-04

2735 Systematic errors in connectivity inferred from activity in strongly coupled recurrent circuits

Das, A.; Fiete, I. R.

10.1101/512053 — neuroscience — Posted on 2019-01-04

2736 Factors associated with adherence to the Integrated Management of Childhood Illness (IMCI) guidelines for under-five years’ old care in Burkina Faso primary health care facilities

Traore, S. A.; SOMDA, S. M. A.; Kiendrebeogo, J. A.; Koulidiaty, J. L.; Robyn, P. J.; Hien, H.; Meda, N.

10.1101/510099 — epidemiology — Posted on 2019-01-04

2737 Avian ANP32B does not support influenza A virus polymerase and influenza A virus relies exclusively on ANP32A in chicken cells.

Long, J. S.; Idoko-Akoh, A.; Mistry, B.; Goldhill, D. H.; Staller, E.; Schreyer, J.; Ross, C.; Goodbourn, S.; Shelton, H.; Skinner, M. A.; Sang, H. M.; McGrew, M. J.; Barclay, W. S.

10.1101/512012 — microbiology — Posted on 2019-01-04

2738 Mixture of Experts for Predicting Antibody-Antigen Binding Affinity from Antigen Sequence

Pittala, S.; Bailey-Kellogg, C.

10.1101/511360 — immunology — Posted on 2019-01-04

2739 Rtn4a promotes exocytosis in mammalian cells while ER morphology does not necessarily affect exocytosis and translation

Mukherjee, R. N.; Zhang, Z.; Levy, D. L.

10.1101/512129 — cell biology — Posted on 2019-01-04

2740 IFT88 controls NuMA enrichment at k-fibers minus-endsto facilitate their reincorporation into mitotic spindles

TAULET, N.; DOUANIER, A.; VITRE, B.; ANGUILLE, C.; MAURIN, J.; DROMARD, Y.; GEORGET, V.; DELAVAL, B.

10.1101/512061 — cell biology — Posted on 2019-01-04

2741 Characterizing gene tree conflict in plastome-inferred phylogenies

Walker, J. F.; Stull, G. W.; Walker-Hale, N.; Vargas, O. M.; Larson, D. A.

10.1101/512079 — evolutionary biology — Posted on 2019-01-04

2742 Post exam analysis: Implication for intervention

Tsegaye, K. N.

10.1101/510081 — scientific communication and education — Posted on 2019-01-04

2743 Management of family relationship informationfor a three-generation cohort study

Shimokawa, K.; Ishikuro, M.; Obara, T.; Metoki, H.; Mizuno, S.; Nagaie, S.; Nagai, M.; Yamanaka, C.; Matsubara, H.; Kato, M.; Sato, Y.; Ogishima, S.; Takai, T.; Kikuya, M.; Hozawa, A.; Nagami, F.; Kuriyama, S.; Kinoshita, K.; Yamamoto, M.; Tanaka, H.

10.1101/510073 — epidemiology — Posted on 2019-01-04

2744 Dynamics of bacterial cell proliferation inhibited by specific proteins for effective horizontal transmission of the integrative and conjugative element ICEclc

Takano, S.; Koto, A.; Miyazaki, R.

10.1101/512285 — microbiology — Posted on 2019-01-04

2745 Structural Differences Between the Woodchuck Hepatitis Virus Core Protein in Dimer and Capsid States Indicate Entropic and Conformational Regulation of Assembly

Zhao, Z.; Wang, J. C.-Y.; Gonzalez-Gutierrez, G.; Venkatakrishnan, B.; Zlotnick, A.

10.1101/512319 — biophysics — Posted on 2019-01-04

2746 Combined Transcriptomics and Proteomics Forecast Analysis for Potential Genes Regulating the Columbian Plumage Color in Chickens

WANG, X.; Li, D.; Song, S.; Zhang, Y.; Li, Y.; Wang, X.; Liu, D.; Zhang, C.; Cao, Y.; Fu, Y.; Han, R.; Li, W.; Liu, X.; Sun, G.; Li, G.; Tian, Y.; Li, Z.; Kang, X.

10.1101/512202 — molecular biology — Posted on 2019-01-04

2747 β-glucan dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

Pazhakh, V.; Ellett, F.; O'Donnell, J.; Pase, L.; Schulze, K. E.; Greulich, R. S.; Reyes-Aldasoro, C. C.; Croker, B. A.; Andrianopoulos, A.; Lieschke, G. J.

10.1101/512228 — cell biology — Posted on 2019-01-04

2748 Modelling the transport of fluid through heterogeneous, whole tumours in silico

Sweeney, P. W.; d'Esposito, A.; Walker-Samuel, S.; Shipley, R. J.

10.1101/512236 — cancer biology — Posted on 2019-01-04

2749 Molecular basis of P major human rotavirus VP8* domain interactions with histo-blood group antigens

Xu, S.; Liu, Y.; Tan, M.; Zhong, W.; Zhao, D.; Jiang, X.; Kennedy, M. A.

10.1101/512301 — biochemistry — Posted on 2019-01-04

2750 Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

Malyutina, A.; Majumder, M. M.; Wang, W.; Pessia, A.; Heckman, C. A.; Tang, J.

10.1101/512244 — pharmacology and toxicology — Posted on 2019-01-04

2751 Experimentally-constrained biophysical models of tonic and burst firing modes in thalamocortical neurons

Iavarone, E.; Yi, J.; Shi, Y.; Zandt, B.-J.; O'Reilly, C.; Van Geit, W.; Rossert, C.; Markram, H.; Hill, S. L.

10.1101/512269 — neuroscience — Posted on 2019-01-04

2752 Viral infection enhances vomocytosis of intracellular fungi via Type I interferons

Seoane, P. I.; Taylor-Smith, L. M.; Stirling, D.; Bell, L. C. K.; Noursadeghi, M.; Bailey, D.; May, R. C.

10.1101/512293 — microbiology — Posted on 2019-01-04

2753 The impact of Temporal Artery Biopsy for the diagnosis of Giant Cell Arteritis in clinical practice in a tertiary University Hospital

Kaltsonoudis, E.; Pelechas, E.; Papoudou-Bai, A.; Markatseli, T. E.; Elisaf, M.; Voulgari, P. V.; Drosos, A.; Kaltsonoudis Evripidis, Pelechas Eleftherios, Papoudou-Bai Alexandra, Markatseli E. Theodora, Elisaf,

10.1101/512137 — epidemiology — Posted on 2019-01-04

2754 Are sleep spindles poised on supercritical Hopf bifurcations?

Ospeck, M.

10.1101/512145 — neuroscience — Posted on 2019-01-04

2755 The evolution of a super-swarm of foot-and-mouth disease virus in cattle

Arzt, J.; Fish, I.; Pauszek, S. J.; Johnson, S. L.; Chain, P. S.; Rai, D. K.; Rieder, E.; Goldberg, T. L.; Rodriguez, L. L.; Stenfeldt, C.

10.1101/512178 — microbiology — Posted on 2019-01-04

2756 Forest canopy, a proxi of light intensity, arrests Pinus radiata invasion: basic science to conserve the Coastal Maulino forest, Central Chile.

Bustamante, R. O.; Gomez, P.; San Martin, J.; MUrua, M.; Goncalves, E.

10.1101/512194 — ecology — Posted on 2019-01-04

2757 Mobile learning for English language learning assessment and evaluation: A review

Elaish, M. M.; Shuib, L.

10.1101/512186 — bioinformatics — Posted on 2019-01-04

2758 Towards an optimised processing pipeline for diffusion MRI data: Effects of artefact corrections on diffusion metrics and their age associations in UK Biobank

Maximov, I. I.; Alnaes, D.; Westlye, L. T.

10.1101/511964 — neuroscience — Posted on 2019-01-04

2759 Increased spontaneous EEG signal diversity during stroboscopically-induced altered states of consciousness

Schwartzman, D. J.; Schartner, M. M.; Ador, B. B.; Simonelli, F.; Chang, A. Y.- C.; Seth, A. K.

10.1101/511766 — neuroscience — Posted on 2019-01-04

2760 Phylogenomics within the Anthonotha clade (Detarioideae, Leguminosae) reveals a high diversity in floral trait shifts and a general trend towards organ number reduction

Ojeda, D.; Koenen, E.; Cervantes Arango, S.; de la Estrella, M.; Banguera-Hinestroza, E.; Janssens, S.; Migliore, J.; Demenou, B.; Bruneau, A.; Forest, F.; Hardy, O.

10.1101/511949 — evolutionary biology — Posted on 2019-01-04

2761 EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

Matthaeus, C.; Lahmann, I.; Kunz, S.; Jonas, W.; Melo, A. A.; Lehmann, M.; Larsson, E.; Lundmark, R.; Hauke, V.; Mueller, D. N.; Schuermann, A.; Birchmeier, C.; Daumke, O.

10.1101/511709 — cell biology — Posted on 2019-01-04

2762 Data-driven spectral analysis for coordinative structures in periodic systems with unknown and redundant dynamics

Fujii, K.; Takeishi, N.; Kibushi, B.; Kouzaki, M.; Kawahara, Y.

10.1101/511642 — neuroscience — Posted on 2019-01-04

2763 Divergence in gut microbial communities mirrors a social group fission event in a black-and-white colobus monkey (Colobus vellerosus)

Goodfellow, C.; Whitney, T.; Christie, D.; Sicotte, P.; Wikberg, E.; Ting, N.

10.1101/511618 — ecology — Posted on 2019-01-04

2764 BMP4 patterns Smad activity and generates stereotyped cell fate organisation in spinal organoids

Duval, N.; Vaslin, C.; Barata, T. C.; Nedelec, S.; Ribes, V. C.

10.1101/511899 — developmental biology — Posted on 2019-01-04

2765 Annotated bacterial chromosomes from frame-shift-corrected long read metagenomic data

Arumugam, K.; Bagci, C.; Bessarab, I.; Beier, S.; Buchfink, B.; Gorska, A.; Qiu, G.; Huson, D. H.; Williams, R. B.

10.1101/511683 — bioinformatics — Posted on 2019-01-04

2766 Distributed DNA-based Communication in Populations of Synthetic Protocells

Joesaar, A.; Yang, S.; Bogels, B.; van der Linden, A.; Kumar, P.; Dalchau, N.; Phillips, A.; Mann, S.; de Greef, T.

10.1101/511725 — synthetic biology — Posted on 2019-01-04

2767 The California Environmental DNA \"CALeDNA\" Program

Meyer, R.; Curd, E. E.; Schweizer, T.; Gold, Z.; Ruiz Ramos, D.; Shirazi, S.; Kandlikar, G.; Kwan, W.-Y.; Lin, M.; Friese, A.; Moberg-Parker, J.; Munguia Ramos, M.; Shapiro, B.; Sexton, J.; Pipes, L.; Garcia Vedrenne, A.; Palacios Mejia, M.; Aronson, E.; Moore, T.; Nielsen, R.; Lewin, H.; Barber, P.; Wall, J.; Kraft, N.; Wayne, R.

10.1101/503383 — scientific communication and education — Posted on 2019-01-04

2768 Rapid memory reactivation at movie event boundaries promotes episodic encoding

Silva, M.; Baldassano, C.; Fuentemilla, L.

10.1101/511782 — neuroscience — Posted on 2019-01-04

2769 Investigating the influence of extraction methodology, and certain other experimental parameters on bacterial response to selected quorum-modulatory plant extracts

Patel, P.; Joshi, C.; Kothari, V.

10.1101/511733 — microbiology — Posted on 2019-01-04

2770 LIDAR explains diversity of plants, fungi, lichens and bryophytes across multiple habitats and large geographic extent

Moeslund, J. E.; Zlinszky, A.; Ejrnaes, R.; Brunbjerg, A. K.; Bocher, P. K.; Svenning, J.-C.; Normand, S.

10.1101/509794 — ecology — Posted on 2019-01-04

2771 Coupling water fluxes with cell wall mechanics in a multicellular model of plant development

Cheddadi, I.; Genard, M.; Bertin, N.; Godin, C.

10.1101/511717 — biophysics — Posted on 2019-01-04

2772 Interaction of HelQ helicase with RPA modulates RPA-DNA binding and stimulates HelQ to unwind DNA through a protein roadblock.

Northall, S. J.; Jenkins, T.; Ptchelkine, D.; Taresco, V.; Cooper, C.; Soultanas, P.; Bolt, E.

10.1101/511758 — biochemistry — Posted on 2019-01-04

2773 Controlling noisy expression through auto regulation of burst frequency and protein stability

Bokes, P.; Singh, A.

10.1101/511774 — systems biology — Posted on 2019-01-04

2774 An EDS1-SAG101 complex functions in TNL-mediated immunity in Solanaceae

Gantner, J.; Ordon, J.; Kretschmer, C.; Guerois, R.; Stuttmann, J.

10.1101/511956 — plant biology — Posted on 2019-01-04

2775 Role of MPK4 in pathogen-associated molecular pattern-triggered alternative splicing in Arabidopsis

Jeremie, B.; Mariappan, K. G.; Blein, T.; Volz, R.; Crespi, M.; Hirt, H.

10.1101/511980 — plant biology — Posted on 2019-01-04

2776 Abl signaling shapes the intrinsic fluctuations of actin to direct growth of a pioneer axon in Drosophila

Clarke, A.; McQueen, P.; Fang, H.-Y.; Kannan, R.; Wang, V.; McCreedy, E.; Wincovitch, S.; Giniger, E.

10.1101/511840 — cell biology — Posted on 2019-01-04

2777 Distinguishing Closely Related Pancreatic Cancer Subtypes In Vivo by 13C Glucose MRI without Hyperpolarization

Kishimoto, S.; Brender, J. R.; Matsumoto, S.; Seki, T.; Oshima, N.; Merkle, H.; Reed, G.; Chen, A. P.; Ardenkjaer-Larsen, J. H.; Munasinghe, J.; Saito, K.; Yamamoto, K.; Choyke, P.; Mitchell, J.; Krishna, M. C.

10.1101/511543 — cancer biology — Posted on 2019-01-04

2778 Functional Near-Infrared Spectroscopy (fNIRS) informed neurofeedback: regional-specific modulation of lateral orbitofrontal activation and cognitive flexibility

Li, K.; Jiang, Y.; Gong, Y.; Zhao, W.; Zhao, Z.; Liu, X.; Kendrick, K.; Zhu, C.; Becker, B.

10.1101/511824 — neuroscience — Posted on 2019-01-04

2779 Identifying small proteins by ribosome profiling with stalled initiation complexes

Weaver, J. S.; Mohammad, F.; Buskirk, A.; Storz, G.

10.1101/511675 — microbiology — Posted on 2019-01-04

2780 Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer

Ha, K.; Fujita, M.; Karlic, R.; Yang, S.; Hoshida, Y.; Polak, P.; Nakagawa, H.; Kim, H.-G.; Lee, H. J.

10.1101/511790 — genomics — Posted on 2019-01-04

2781 Insulator Activities of Nucleosome-Excluding DNA Sequences Without Bound Chromatin Looping Proteins

Matsushima, Y.; Sakamoto, N.; Awazu, A.

10.1101/511600 — genomics — Posted on 2019-01-04

2782 Genomics and transcriptomics to unravel sex determination pathway and its evolution in sand flies

Petrella, V.; Aceto, S.; Colonna, V.; Saccone, G.; Sanges, R.; Polanska, N.; Volf, P.; Gradoni, L.; Bongiorno, G.; Salvemini, M.

10.1101/510586 — genomics — Posted on 2019-01-04

2783 Effects of phenotypic robustness on adaptive evolutionary dynamics

Rigato, E.; Fusco, G.

10.1101/511691 — evolutionary biology — Posted on 2019-01-04

2784 ABC transporters confer multidrug resistance to Drosophila intestinal stem cells

Dayton, H.; DiRusso, J.; Kolbert, K.; Williamson, O.; Balciunaite, A.; D'Souza, E.; Becker, K.; Hosage, E.; Issa, M.; Liu, V.; Viswanatha, R.; Kondo, S.; Markstein, M.

10.1101/511584 — cell biology — Posted on 2019-01-04

2785 Recording of \"sonic attacks\" on U.S. diplomats in Cuba spectrally matches the echoing call of a Caribbean cricket

Stubbs, A. L.; Montealegre-Z, F.

10.1101/510834 — biophysics — Posted on 2019-01-04

2786 A Hybrid Deep Clustering Approach for Robust Cell Type Profiling Using Single-cell RNA-seq Data

Srinivasan, S.; Johnson, N. T.; Korkin, D.

10.1101/511626 — bioinformatics — Posted on 2019-01-04

2787 A device to collect exhaled breath to study biomarkers in small animal models

Liu, Y.; Hou, Y.; Hua, Y.; Gao, Y.

10.1101/511931 — biochemistry — Posted on 2019-01-04

2788 Setting off the Alarms: Candida albicans Elicits Pro-Inflammatory Differential Gene Expression in Intestinal Peyer’s Patches

Singh, N.; Kim, H. C.; Song, R.; Dhinsa, J.; Torres, S. R.; De Jesus, M.

10.1101/511667 — microbiology — Posted on 2019-01-04

2789 The spread of resistance to imidacloprid is restricted by thermotolerance in natural populations of Drosophila melanogaster

Fournier-Level, A.; Good, R. T.; Wilcox, S.; Rane, R. V.; Schiffer, M.; Chen, W.; Battlay, P.; Perry, T.; Batterham, P.; Hoffmann, A. A.; Robin, C.

10.1101/511519 — evolutionary biology — Posted on 2019-01-04

2790 Discovery of New Classes of Glycine transporter 2 (GlyT2) Inhibitors and Study of GlyT2 Selectivity by Combination of Novel Structural Based Virtual Screening Approach and Free Energy Perturbation (FEP+) Calculations

Sirimulla, S.; Miranda-Arango, M.; Padilla, E.; Sirimulla, S.

10.1101/510487 — biophysics — Posted on 2019-01-04

2791 The genetic basis of cis-regulatory divergence between the subspecies of cultivated rice (Oryza sativa)

Campbell, M. T.; Du, Q.; Liu, K.; Sharma, S.; Zhang, C.; Walia, H.

10.1101/511550 — genomics — Posted on 2019-01-04

2792 Multiple layers of cryptic genetic variation underlie a yeast complex trait

Lee, J. T.; Coradini, A. L. V.; Shen, A.; Ehrenreich, I. M.

10.1101/465278 — genetics — Posted on 2019-01-04

2793 The genetics and genome-wide screening of regrowth loci, a key component of perennialism in Zea diploperennis

Ma, A.; Qiu, Y.; Raihan, T.; Dahal, S.; Zhuang, Y.; Galla, A.; Auger, D. L.; Yen, Y.

10.1101/388256 — plant biology — Posted on 2019-01-04

2794 The translatome of adult cortical axons is regulated by learning in vivo

Ostroff, L. E.; Santini, E.; Sears, R.; Deane, Z.; LeDoux, J.; Lhakhang, T.; Tsirigos, A.; Heguy, A.; Klann, E.

10.1101/502419 — neuroscience — Posted on 2019-01-04

2795 Differential regulation of native and learned behavior by creb1/crh-1 in Caenorhabditis elegans

Dahiya, Y.; Rose, S.; Thapliyal, S.; Bhardwaj, S.; Prasad, M.; Babu, K.

10.1101/508986 — neuroscience — Posted on 2019-01-04

2796 In vivo microscopy reveals the impact of Pseudomonas aeruginosa social interactions on host colonization

Rezzoagli, C.; Granato, E.; Kuemmerli, R.

10.1101/488262 — microbiology — Posted on 2019-01-04

2797 Exploratory analyses suggest less cognitive decline with nilvadipine treatment in very mild Alzheimer’s disease subjects

Abdullah, L.; Crawford, F.; Langlois, H.; Hendrix, S.; Kennelly, S.; Lawlor, B.; Mullan, M.

10.1101/345652 — clinical trials — Posted on 2019-01-04

2798 Chloroplast competition is controlled by lipid biosynthesis in evening primroses

Sobanski, J.; Giavalisco, P.; Fischer, A.; Kreiner, J.; Walther, D.; Schoettler, M. A.; Pellizzer, T.; Golczyk, H.; Obata, T.; Bock, R.; Sears, B. B.; Greiner, S.

10.1101/330100 — genetics — Posted on 2019-01-04

2799 Revealing heterogeneity of brain imaging phenotypes in Alzheimer’s disease based on unsupervised clustering of blood marker profiles

Marti-Juan, G.; Sanroma, G.; Piella, G.; The Alzheimer's Disease Neuroimaging Initiative and the Alzheimer's Disease Metabolomics Consortium,

10.1101/339614 — bioinformatics — Posted on 2019-01-04

2800 Atypical neurogenesis and excitatory-inhibitory progenitor generation in induced pluripotent stem cell (iPSC) from autistic individuals

Adhya, D.; Swarup, V.; Nagy, R.; Shum, C.; Nowosiad, P.; Jozwik, K.; Lee, I.; Skuse, D.; Flinter, F. A.; McAlonan, G.; Mendez, M. A.; Horder, J.; Murphy, D.; Geschwind, D. H.; Price, J.; Carroll, J.; Srivastava, D. P.; Baron-Cohen, S.

10.1101/349415 — neuroscience — Posted on 2019-01-03

2801 CNN-based radiographic acute tibial fracture detection in the setting of open growth plates

Starosolski, Z. A.; Kan, H.; Annapragada, A. V.

10.1101/506154 — bioinformatics — Posted on 2019-01-03

2802 Analysis of >30,000 abstracts suggests higher false discovery rates for oncology journals, especially those with low impact factors

Hall, L. M.; Hendricks, A. E.

10.1101/500660 — scientific communication and education — Posted on 2019-01-03

2803 Carbs versus fat: does it really matter for maintaining lost weight?

Hall, K. D.; Guo, J.

10.1101/476655 — physiology — Posted on 2019-01-03

2804 Structure-Unbinding Kinetics Relationship of p38 MAPK Inhibitors

Ge, X.; Tan, H.; Xie, L.

10.1101/510255 — pharmacology and toxicology — Posted on 2019-01-03

2805 Non-FG-Nups, ELYS and Nup35, coordinate an ordered assembly of FG-Nups on the scaffold of the nuclear pore complex

Konishi, H. A.; Yoshimura, S. H.

10.1101/506469 — cell biology — Posted on 2019-01-03

2806 p62-mediated Selective Autophagy Endows Virus-transformed Cells with Insusceptibility to DNA Damage under Oxidative Stress

Wang, L.; Howell, M.; Sparks-Wallace, A.; Hawkins, C.; Nicksic, C.; Kohne, C.; Hall, K.; Moorman, J.; Yao, Z. Q.; Ning, S.

10.1101/502823 — cancer biology — Posted on 2019-01-03

2807 Green autofluorescence intensity of skin and fingernails: A novel biomarker for non-invasive evaluation of pathological state of blood vessels

Zhang, M.; Wu, D.; Tao, Y.; Li, Y.; Zhang, S.; Chen, X.; Ying, W.

10.1101/403832 — pathology — Posted on 2019-01-03

2808 Systematic identification and characterization of Aedes aegypti long noncoding RNAs

Azlan, A.; Obeidat, S. M.; Yunus, M. A.; Azzam, G.

10.1101/422170 — genetics — Posted on 2019-01-03

2809 Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities

Martin, A. R.; Kanai, M.; Kamatani, Y.; Okada, Y.; Neale, B. M.; Daly, M. J.

10.1101/441261 — genetics — Posted on 2019-01-03

2810 Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

Schork, A.; Hougaard, D.; Nordentoft, M.; Mors, O.; Boerglum, A.; Bo Mortensen, P.; Wray, N. R.; Werge, T.

10.1101/487116 — genetics — Posted on 2019-01-03

2811 Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

Sullivan, M. R.; Danai, L. V.; Lewis, C. A.; Chan, S. H.; Gui, D. Y.; Kunchok, T.; Dennstedt, E. A.; Vander Heiden, M. G.; Muir, A.

10.1101/492652 — cancer biology — Posted on 2019-01-03

2812 Atypical neurogenesis and excitatory-inhibitory progenitor generation in induced pluripotent stem cell (iPSC) from autistic individuals

10.1101/349415 — neuroscience — Posted on 2019-01-03

2813 Determining the replication kinetics and cellular tropism of the ruminant-associated Influenza D virus on primary human airway epithelial cells

Holwerda, M.; Laloli, L.; Stuermer, I.; Portmann, J.; Stalder, H.; Dijkman, R.

10.1101/395517 — microbiology — Posted on 2019-01-03

2814 Adaptive phenotypic divergence in an annual grass differs across biotic contexts

O'Brien, A. M.; Sawers, R. J. H.; Strauss, S. Y.; Ross-Ibarra, J.

10.1101/382770 — evolutionary biology — Posted on 2019-01-03

2815 A biologically driven directional change in susceptibility to global-scale glaciation during the Precambrian-Cambrian transition

Boyle, R.; Loscher, C. R.

10.1101/359422 — paleontology — Posted on 2019-01-03

2816 Nod2 protects remote small intestinal sites in case of colonic inflammation.

Hugot, J.-P.; Al Nabhani, Z.; Berrebi, D.; Martinez-Vinson, C.; Montcuquet, N.; Dietrich, G.; Singh, G.; Turner, J. R.; Madre, C.; Roy, M.; Ogier-Denis, E.; Dussaillant, M.; Cerf-Bensussan, N.; Zouali, H.; Jung, C.; Daniel, F.; Barreau, F.

10.1101/510933 — immunology — Posted on 2019-01-03

2817 Aggregation-prone peptides modulate interferon gamma functionality in naturally occurring protein nanoparticles

Carratala, J. V.; Cano-Garrido, O.; Sanchez, J. M.; Membrado, C.; Perez, E.; Conchillo-Sole, O.; Daura, X.; Sanchez-Chardi, A.; Villaverde, A.; Aris, A.; Garcia-Fruitos, E.; Ferrer-Miralles, N.

10.1101/510636 — microbiology — Posted on 2019-01-03

2818 The axonal actin-spectrin lattice acts as shock absorbers to protect neurons from stretch-induced damage

Dubey, S.; Bhembre, N.; Ghose, A.; Callan-Jones, A.; Pullarkat, P. A.

10.1101/510560 — biophysics — Posted on 2019-01-03

2819 Generating real-world tumor burden endpoints from electronic health record data: Comparison of RECIST, radiology-anchored, and clinician-anchored approaches for abstracting real-world progression in non-small cell lung cancer

Griffith, S. D.; Tucker, M.; Bowser, B.; Calkins, G.; Chang, C.-h.; Guardino, E.; Khozin, S.; Kraut, J.; Miksad, R.; You, P.; Schrag, D.; Abernethy, A. P.

10.1101/504878 — bioinformatics — Posted on 2019-01-03

2820 Computational Causal Modeling of the Dynamic Biomarker Cascade in Alzheimer’s Disease

Petrella, J. R.; Hao, W.; Rao, A.; Doraiswamy, P. M.; Alzheimer's Disease Computational Modeling Initiative,

10.1101/313353 — neuroscience — Posted on 2019-01-03

2821 Combining 3D-MOT with motor and perceptual decision-making tasks: conception of a life-sized virtual perceptual-cognitive training paradigm

Romeas, T.; Chaumillon, R.; Labbe, D.; Faubert, J.

10.1101/511337 — neuroscience — Posted on 2019-01-03

2822 Mitotic gene bookmarking by RUNX1 contributes to stabilization of the normal mammary epithelial phenotype

Rose, J. T.; Boyd, J. R.; Gordon, J. A.; Kang, M.; Moskovitz, E.; Bouffard, N. A.; Fritz, A. J.; Illendula, A.; Bushweller, J. H.; Lian, J. B.; Stein, J. L.; Stein, G. S.; Zaidi, S.

10.1101/511410 — cancer biology — Posted on 2019-01-03

2823 Exploring Single-Cell Data with Deep Multitasking Neural Networks

Amodio, M.; van Dijk, D.; Srinivasan, K.; Chen, W. S.; Mohsen, H.; Moon, K. R.; Campbell, A.; Zhao, Y.; Wang, X.; Venkataswamy, M.; Desai, A.; V., R.; Kumar, P.; Montgomery, R.; Wolf, G.; Krishnaswamy, S.

10.1101/237065 — bioinformatics — Posted on 2019-01-03

2824 Associations between vascular risk factors and brain MRI indices in UK Biobank

Cox, S. R.; Lyall, D. M.; Ritchie, S. J.; Bastin, M. E.; Harris, M. A.; Buchanan, C. R.; Fawns-Ritchie, C.; Barbu, M. C.; de Nooij, L.; Reus, L. M.; Alloza, C.; Shen, X.; Neilson, E.; Alderson, H. L.; Hunter, S.; Liewald, D. C.; Whalley, H. C.; McIntosh, A. M.; Lawrie, S. J.; Pell, J. P.; Tucker-Drob, E. M.; Wardlaw, J. M.; Gale, C. R.; Deary, I. J.

10.1101/511253 — neuroscience — Posted on 2019-01-03

2825 YeasTSS: An Integrative Web Database of Yeast Transcription Start Sites

McMillan, J.; Lu, Z.; Rodriguez, J. S.; Ahn, T.-H.; Lin, Z.

10.1101/511477 — bioinformatics — Posted on 2019-01-03

2826 WDR76 promotes MLL-rearranged leukemia via selective recognition of 5-hydroxymethylcytosine in DNA

Malecek, K. E.; Weng, H.; Sullivan, M. A.; Kokontis, C. Y.; Werner, M. S.; Chen, J.; Ruthenburg, A. J.

10.1101/511394 — biochemistry — Posted on 2019-01-03

2827 iDamage: a method to integrate modified DNA into the yeast genome

Maslowska, K.; Laureti, L.; Pages, V.

10.1101/510966 — molecular biology — Posted on 2019-01-03

2828 Toxoplasma F-Box Protein 1 is Required for Daughter Cell Scaffold Function During Parasite Replication

Baptista, C. G.; Lis, A.; Deng, B.; Dittmar, A.; West, C. M.; Blader, I. J.

10.1101/511386 — microbiology — Posted on 2019-01-03

2829 β1 integrin is a sensor of blood flow direction

Xanthis, I.; Souilhol, C.; Serbanovic-Canic, J.; Roddie, H.; Kalli, A.; Fragiadaki, M.; Wong, R.; Shah, D.; Askari, J.; Canham, L.; Akhtar, N.; Feng, S.; Ridger, V.; Waltho, J.; Pinteaux, E.; Humphries, M.; Bryan, M.; Evans, P.

10.1101/511261 — cell biology — Posted on 2019-01-03

2830 Tumor Necrosis Factor induces pathogenic programmed macrophage necrosis in tuberculosis through a mitochondrial-lysosomal-endoplasmic reticulum circuit

Roca, F.; Redmond, S.; Ramakrishnan, L.

10.1101/511436 — cell biology — Posted on 2019-01-03

2831 Dissecting the heterogeneity of DENV vaccine-elicited cellular immunity using single-cell RNA sequencing and cellular metabolic profiling

Waickman, A. T.; Victor, K.; Li, T.; Hatch, K.; Rutvisuttinnunt, W.; Medin, C.; Gabriel, B.; Jarman, R. G.; Friberg, H.; Currier, J. R.

10.1101/511428 — immunology — Posted on 2019-01-03

2832 Professional Swimmers and Normal Populations have Different Patterns of Epidermal Green Autofluorescence

Tao, Y.; Zhang, M.; Li, Y.; Shen, X.; Ying, W.

10.1101/510891 — biophysics — Posted on 2019-01-03

2833 Structure and function of a 9.6 megadalton bacterial iron storage compartment

Giessen, T. W.; Orlando, B. J.; Verdegaal, A. A.; Chambers, M. G.; Gardener, J.; Bell, D. C.; Birrane, G.; Liao, M.; Silver, P. A.

10.1101/511345 — biochemistry — Posted on 2019-01-03

2834 Changes in behavioral state account for the modulation of cerebellar learning by cannabinoid receptors

Albergaria, C.; Silva, N. T.; Darmohray, D.; Carey, M. R.

10.1101/511113 — neuroscience — Posted on 2019-01-03

2835 Macrophages enforce the blood nerve barrier

Malong, L.; Napoli, I.; White, I. J.; Steirli, S.; Bossio, A.; Lloyd, A. C.

10.1101/493494 — neuroscience — Posted on 2019-01-03

2836 Selection and characterization of a reovirus mutant with improved thermostability

Snyder, A. J.; Danthi, P.

10.1101/511352 — microbiology — Posted on 2019-01-03

2837 Differential expression feature extraction (DEFE) and its application in RNA-seq data analysis

Pan, Y.; Li, Y.; Liu, Z.; Surendra, A.; Wang, L.; Foroud, N. A.; Goyal, R. K.; Ouellet, T.; Fobert, P. R.

10.1101/511188 — genomics — Posted on 2019-01-03

2838 Cytoplasmic volume and limiting nucleoplasmin scale nuclear size during Xenopus laevis development

Chen, P.; Tomschik, M.; Nelson, K.; Oakey, J.; Gatlin, J. C.; Levy, D. L.

10.1101/511451 — cell biology — Posted on 2019-01-03

2839 Multiplexed, sequential secretion analysis of the same single cells reveals distinct effector response dynamics dependent on the initial basal state

Chen, Z.; Lu, Y.; Zhang, K.; Xiao, Y.; Lu, J.; Fan, R.

10.1101/511238 — bioengineering — Posted on 2019-01-03

2840 Identification of Factors Complicating Bioluminescence Imaging

Yeh, H.-W.; Wu, T.; Chen, M.; Ai, H.

10.1101/511501 — biochemistry — Posted on 2019-01-03

2841 Discovery of biased orientation of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2019-01-03

2842 A general decrease of normalized ncDNA in evolution

Lobo-Cabrera, F. J.

10.1101/511196 — evolutionary biology — Posted on 2019-01-03

2843 Using Twitter To Generate Signals For The Enhancement Of Syndromic Surveillance Systems: Semi-Supervised Classification For Relevance Filtering in Syndromic Surveillance

Edo-Osagie, O.; Smith, G.; Lake, I.; Edeghere, O.; De La Iglesia, B.

10.1101/511071 — epidemiology — Posted on 2019-01-03

2844 Variation in reported human head tissue electrical conductivity values

McCann, H.; Pisano, G.; Beltrachini, L.

10.1101/511006 — neuroscience — Posted on 2019-01-03

2845 Rigid Foot Soles Improve Balance in Beam Walking

Huber, M. E.; Chiovetto, E.; Giese, M.; Sternad, D.

10.1101/510990 — neuroscience — Posted on 2019-01-03

2846 Computational modeling of anthocyanin pathway evolution

Wheeler, L. C.; Smith, S. D.

10.1101/511089 — evolutionary biology — Posted on 2019-01-03

2847 OGRE: Overlap Graph-based metagenomic Read clustEring

Balvert, M.; Hauptfeld, T.; Schoenhuth, A.; Dutilh, B. E.

10.1101/511014 — bioinformatics — Posted on 2019-01-03

2848 Enjoy The Violence: Is appreciation for extreme music the result of cognitive control over the threat response system?

Ollivier, R.; Goupil, L.; Liuni, M.; Aucouturier, J.-J.

10.1101/510008 — neuroscience — Posted on 2019-01-03

2849 Fundamental Law of Memory Recall

Naim, M.; Katkov, M.; Tsodyks, M.

10.1101/510750 — neuroscience — Posted on 2019-01-03

2850 Doubled haploid based parental lines are most suitable in predicting heterosis using microsatellites and in development of highly heterotic F1 hybrids in Brassica oleracea

Singh, S.; Dey, S.; Bhatia, R.; Kumar, R.; Sharma, K.; Behera, T. K.

10.1101/511055 — plant biology — Posted on 2019-01-03

2851 Contrasting paternal and maternal genetic histories of Thai and Lao populations

Kutanan, W.; Kampuansai, J.; Srikummool, M.; Brunelli, A.; Ghirotto, S.; Arias, L.; Macholdt, E.; Huebner, A.; Schroeder, R.; Stoneking, M.

10.1101/509752 — genetics — Posted on 2019-01-03

2852 Factors Associated with Suicidal Ideation and Suicidal Attempts among Adolescent Students in Nepal: Findings from Global School Based Students Health Survey

Pandey, A. R.; Bista, B.; Dhungana, R. R.; Aryal, K. K.; Chalise, B.; Dhimal, M.

10.1101/511105 — epidemiology — Posted on 2019-01-03

2853 The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

Chakraborty, A.; Laukka, T.; Myllykoski, M.; Ringel, A.; Booker, M.; Tolstorukov, M.; Meng, Y.; Meier, S.; Jennings, R.; Creech, A.; Herbert, Z.; Spinelli, J.; McBrayer, S.; Olenchock, B.; Jaffe, J.; Haigis, M.; Beroukhim, R.; Signoretti, S.; Koivunen, P.; Kaelin, W. G.

10.1101/510479 — biochemistry — Posted on 2019-01-03

2854 Assessment of gibberellin (GA4+7) mediated changes on grain filling, hormonal behaviour and antioxidants in high-density maize (Zea Mays L.)

Cui, W.; Zuo, B.; Song, Q.; Han, Q.; Jia, Z.

10.1101/511063 — plant biology — Posted on 2019-01-03

2855 Glia-neuron interactions underlie state transitions to generalized seizures

Diaz Verdugo, C.; Myren-Svelstad, S.; Deneubourg, C.; Pelgrims, R.; Muto, A.; Kawakami, K.; Jurisch-Yaksi, N.; Yaksi, E.

10.1101/509521 — neuroscience — Posted on 2019-01-03

2856 Carbohydrate, glutathione, and polyamine metabolism are central to Aspergillus flavus oxidative stress responses over time

Guo, B.; Fountain, J.; Yang, L.; Pandey, M.; Bajaj, P.; Alexander, D.; Chen, S.; Kemerait, R.; Varshney, R.

10.1101/511170 — microbiology — Posted on 2019-01-03

2857 An improved control efficacy against tobacco bacterial wilt by an engineered Pseudomonas mosselii expressing the ripAA gene from phytopathogenic Ralstonia solanacearum

Zhuo, T.; Chen, S.; Fan, X.; Hu, X.; Zou, H.

10.1101/510628 — microbiology — Posted on 2019-01-03

2858 Demographic and genetic structure of a severely fragmented population of the endangered hog deer (Axis porcinus) in the Indo- Burma biodiversity hotspot

Angom, S.; Tuboi, C.; Ghazanfar Ullah, M.; Hussain, S. A.; Sangeeta Angom, Chongpi Tuboi, Mirza Ghazanfar Ullah, Syed Ainul Hussain,

10.1101/511154 — genetics — Posted on 2019-01-03

2859 Dissection and validation of minor quantitative trait loci (QTLs) conferring grain size and weight in rice

Sun, P.; Zheng, Y.; Li, P.; Ye, H.; Zhou, H.; Gao, G.; He, Y.

10.1101/511139 — genetics — Posted on 2019-01-03

2860 Oxidative Stress and Biomarker Responses in the Atlantic Halibut After Long Term Exposure to Elevated CO2 and a Range of Temperatures

Carney Almroth, B.; De Souza Bresolin, K.; Jonsson Bergman, E.; Sturve, J.

10.1101/510818 — physiology — Posted on 2019-01-03

2861 Glutamatergic and cholinergic metabotropic modulation induces plateau potentials in hippocampal OLM interneurons

Hagger-Vaughan, N.; Storm, J. F.

10.1101/508382 — neuroscience — Posted on 2019-01-03

2862 Generating quantitative binding landscapes through fractional binding selections, deep sequencing and data normalization

Heyne, M.; Papo, N.; Shifman, J.

10.1101/509984 — biochemistry — Posted on 2019-01-03

2863 Computational Intractability Law Molds the Topology of Biological Networks

Atiia, A. A.; Hopper, C.; Inoue, K.; Vidal, S.; Waldispuhl, J.

10.1101/510495 — systems biology — Posted on 2019-01-03

2864 Integrated high-resolution phenotyping, chlorophyll fluorescence induction kinetics and photosystem II dynamics under water stress and heat in Wheat (Triticum aestivum)

Shanker, A.; Coe, R.; Sirault, X.

10.1101/510701 — plant biology — Posted on 2019-01-03

2865 Faster Cognitive Decline in Dementia due to Alzheimer Disease with Clinically Undiagnosed Lewy Body Disease

Beach, T. G.; Malek-Ahmadi, M. H.; Zamrini, E.; Adler, C. H.; Sabbagh, M. N.; Shill, H. A.; Jacobson, S. A.; Belden, C. M.; Caselli, R. J.; Woodruff, B. K.; Rapscak, S. Z.; Ahern, G. L.; Shi, J.; Caviness, J. N.; Driver-Dunckley, E.; Mehta, S. H.; Shprecher, D. R.; Spann, B. M.; Tariot, P.; Davis, K. J.; Long, K.; Nicholson, L. R.; Intorcia, A.; Glass, M. J.; Walker, J. E.; Callan, M.; Curry, J.; Cutler, B.; Oliver, J.; Arce, R.; Walker, D. G.; Lue, L.-F.; Serrano, G. E.; Sue, L. I.; Chen, K.; Reiman, E. M.

10.1101/510453 — neuroscience — Posted on 2019-01-03

2866 BCR analysis of single-sorted, putative IgE+ memory B cells in food allergy: an ephemeral existence?

Jimenez-Saiz, R.; Ellenbogen, Y.; Bruton, K.; Spill, P.; Sommer, D. D.; Lima, H.; Waserman, S.; Patil, S. U.; Shreffler, W. G.; Jordana, M.

10.1101/510743 — immunology — Posted on 2019-01-03

2867 Multi-locus characterization and phylogenetic inference of Leishmania spp. in snakes from Northwest China

Chen, H.; Li, J.; Zhang, J.; He, J.; Zhang, J.; Zheng, Z.; Chen, D.; Chen, J.

10.1101/511162 — evolutionary biology — Posted on 2019-01-03

2868 Evolution in small steps - A nearly-universal rule of negative selection on codons

Chen, Q.; Lan, A.; Shen, X.; Wu, C.-I.

10.1101/510735 — evolutionary biology — Posted on 2019-01-03

2869 The evolution of life history theory: Bibliometric analysis of an interdisciplinary research area

Nettle, D.; Frankenhuis, W. E.

10.1101/510826 — evolutionary biology — Posted on 2019-01-03

2870 A free-running oscillator times and executes centriole biogenesis

Aydogan, M. G.; Steinacker, T. L.; Mofatteh, M.; Gartenmann, L.; Wainman, A.; Saurya, S.; Conduit, P. T.; Zhou, F. Y.; Boemo, M. A.; Raff, J. W.

10.1101/510875 — cell biology — Posted on 2019-01-03

2871 Overexpression of long noncoding RNA GAS5 suppresses tumorigenesis and development of gastric cancer by sponging miR-106a-5p through the Akt/mToR pathway

Dong, S.; Zhang, X.; Liu, D.

10.1101/510511 — cancer biology — Posted on 2019-01-03

2872 Functional dissection of Alzheimer’s disease brain gene expression signatures in humans and mouse models

Wan, Y.-W.; Al-Ouran, R.; Mangleburg, C. G.; Lee, T. V.; Allison, K.; Neuner, S.; Kaczorowski, C.; Phillip, V.; Howell, G.; Martini-Stoica, H.; Zheng, H.; Kim, J. W.; Dawson, V.; Dawson, T.; Pao, P.-C.; Tsai, L.-H.; Haure-Mirande, J.-V.; Wang, M.; Ehrlich, M. E.; Mei, H.; Zhong, X.; Chakrabarty, P.; Levites, Y.; Golde, T. E.; Levey, A. I.; Accelerating Medicines Partnership-Alzheimer Disease Consortium, ; Logsdon, B.; Mangravite, L.; Liu, Z.; Shulman, J. M.

10.1101/506873 — systems biology — Posted on 2019-01-03

2873 Influence of Vocal Feedback on Emotions Provides Causal Evidence for the Self-Perception Theory

Goupil, L.; Johansson, P.; Hall, L.; Aucouturier, J.-J.

10.1101/510867 — neuroscience — Posted on 2019-01-03

2874 Reduced structural connectivity in Insomnia Disorder

Jespersen, K.; Stevner, A.; Fernandes, H.; Soerensen, S. D.; Van Someren, E.; Kringelbach, M.; Vuust, P.

10.1101/510784 — neuroscience — Posted on 2019-01-03

2875 Construction of synthetic microbiota for reproducible flavor metabolism in Chinese light aroma type liquor produced by solid-state fermentation

Wu, Q.; Wang, S.; Yao, N.; Xu, Y.

10.1101/510610 — microbiology — Posted on 2019-01-03

2876 Bacterial Diversity in Feces of Wild Bald Eagles, Turkey Vultures and Common Ravens from the Pacific Northwest Coast, U.S.A.

Crespo, R.; Dowd, S. E.; Varland, D. E.; Ford, S.; Hamer, T. E.

10.1101/511147 — microbiology — Posted on 2019-01-03

2877 Low Replication Capacity Virus Is Preferentially Transmitted In Mother-To-Child-Transmission But Not In Adult-To-Adult-Transmission Of HIV-1

Adland, E.; Iselin, L.; Roxburgh, F.; Millar, J.; Csala, A.; Naidoo, V.; Noble, C.; Thomas, J.; De'Felice, A.; Szabo, A.; Grayson, N.; Moodley, A.; Dong, K.; Walker, B.; Ndung'u, T.; McInally, S.; Hunter, E.; Goulder, P.

10.1101/510776 — immunology — Posted on 2019-01-03

2878 Discovery of New Mycoviral Genomes Within Publicly Available Fungal Transcriptomic Datasets

Gilbert, K.; Holcomb, E. E.; Allscheid, R. L.; Carrington, J.

10.1101/510404 — genomics — Posted on 2019-01-03

2879 Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features

Barros De Andrade e Sousa, L.; Jonkers, I.; Syx, L.; Chaumell, J.; Picard, C.; Foret, B.; Chen, C.-J.; Lis, J. T.; Heard, E.; Schulz, E. G.; Marsico, A.

10.1101/510198 — genomics — Posted on 2019-01-03

2880 Molecular evolution in large steps - Codon substitutions under positive selection

Chen, Q.; He, Z.; Lan, A.; Wen, H.; Wu, C.-I.

10.1101/510958 — evolutionary biology — Posted on 2019-01-03

2881 Mitochondrial Ca2+ influences photoresponse recovery, metabolism, and mitochondrial localization in cone photoreceptors

Hutto, R. A.; Bisbach, C. M.; Abbas, F.; Brock, D. C.; Cleghorn, W. M.; Parker, E. D.; Bauer, B. H.; Ge, W.; Vinberg, F.; Hurley, J. B.; Brockerhoff, S. E.

10.1101/510792 — cell biology — Posted on 2019-01-03

2882 CSynth: A Dynamic Modelling and Visualisation Tool for 3D Chromatin Structure

Todd, S.; Todd, P.; McGowan, S. J.; Hughes, J. R.; Kakui, Y.; Leymarie, F. F.; Latham, W.; Taylor, S.

10.1101/499806 — bioinformatics — Posted on 2019-01-03

2883 Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach

Logsdon, B.; Perumal, T. M.; Swarup, V.; Wang, M.; Funk, C.; Gaiteri, C.; Allen, M.; Wang, X.; Dammer, E.; Srivastava, G.; Mukherjee, S.; Sieberts, S. K.; Omberg, L.; Dang, K. D.; Eddy, J. A.; Snyder, P.; Chae, Y.; Amberkar, S.; Wei, W.; Hide, W.; Preuss, C.; Ergun, A.; Ebert, P. J.; Airey, D. C.; Carter, G. W.; Mostafavi, S.; Yu, L.; Klein, H.-U.; Collier, D. A.; Golde, T.; Levey, A.; Bennett, D. A.; Estrada, K.; Decker, M.; Liu, Z.; Shulman, J. M.; Zhang, B.; Schadt, E.; De Jager, P. L.; Price, N. D.; Ertekin-Taner, N.; Mangravite, L. M.

10.1101/510420 — systems biology — Posted on 2019-01-03

2884 Informal genomic surveillance of regional distribution of Salmonella Typhi genotypes and antimicrobial resistance via returning travellers

Ingle, D. J.; Nair, S.; Hartman, H.; Ashton, P. M.; Dyson, Z. A.; Day, M.; Freedman, J.; Chattaway, M. A.; Holt, K. E.; Dallman, T. J.

10.1101/510461 — microbiology — Posted on 2019-01-03

2885 Inclusive medical rehabilitation for persons with disability due to leprosy, lymphatic filariasis, and diabetes mellitus: Mapping the gap in three leprosy endemic districts in Indonesia

Denny, H. M.; Darmawan, Y.; Ginandjar, P.; Widjanarko, B.; Sriatmi, A.; Umamah, A.; Sakundarno, M.; Prasetyanti, W.

10.1101/511097 — epidemiology — Posted on 2019-01-03

2886 Variation in Melitaea cinxia gut microbiota is phylogenetically highly structured but only mildly driven by host plant microbiota, sex or parasitism.

Minard, G.; Tikhonov, G.; Ovaskainen, O.; Saastamoinen, M.

10.1101/510446 — ecology — Posted on 2019-01-03

2887 Optimization of the experimental parameters of the ligase cycling reaction

Schlichting, N.; Reinhardt, F.; Jager, S.; Schmidt, M.; Kabisch, J.

10.1101/510768 — bioengineering — Posted on 2019-01-03

2888 Multi-ATOM: Ultrahigh-throughput single-cell quantitative phase imaging with subcellular resolution

Lee, K.; Lau, A.; Tang, A.; Wnag, M.; Mok, A.; Chung, B.; Yan, W.; Shum, H. C.; Cheah, K.; Chan, G.; So, H.; Wong, K.; Tsia, K.

10.1101/510693 — bioengineering — Posted on 2019-01-03

2889 High innate preference for black substrate in the chive gnat, Bradysia odoriphaga (Diptera: Sciaridae)

An, L.; Fan, F.; Lunau, K.; Li, M.; Yang, X.; Wei, G.

10.1101/511121 — animal behavior and cognition — Posted on 2019-01-03

2890 Plants emit remotely detectable ultrasounds that can reveal plant stress

Khait, I.; Sharon, R.; Perelman, R.; Boonman, A.; Yovel, Y.; Hadany, L.

10.1101/507590 — plant biology — Posted on 2019-01-03

2891 Oral thermosensing by murine trigeminal neurons:modulation by capsaicin, menthol, and mustard oil

Leijon, S. C. M.; Neves, A. F.; Breza, J. M.; Simon, S. A.; Chaudhari, N.; Roper, S.

10.1101/486480 — neuroscience — Posted on 2019-01-03

2892 A staphylococcal cyclophilin carries a single domain and unfolds via the formation of an intermediate that preserves cyclosporin A binding activity

Seal, S.; Polley, S.; Sau, S.

10.1101/511048 — biochemistry — Posted on 2019-01-03

2893 Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease

Corbin, L. J.; Taylor, A. E.; White, S. J.; Williams, C. M.; Taylor, K.; van den Bosch, M. T.; Teasdale, J. E.; Jones, M.; Bond, M.; Harper, M. T.; Falk, L.; Groom, A.; Hazell, G. G. J.; Paternoster, L.; Munafo, M. R.; Nordestgaard, B. G.; Tybjaerg-Hansen, A.; Bojesen, S. E.; Relton, C.; Min, J. L.; Davey Smith, G.; Mumford, A. D.; Poole, A. W.; Timpson, N. J.

10.1101/473728 — epidemiology — Posted on 2019-01-03

2894 Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women

Foucaut, A.-M.; Faure, C.; Julia, C.; Czernichow, S.; Levy, R.; Dupont, C.; Isbelle Aknin, Isabelle Cedrin-Durnerin, Steven Cens, Pascale Chavatte-Palmer, Serge Hercberg, Khale,

10.1101/511030 — epidemiology — Posted on 2019-01-03

2895 Morphological and Genomic Characterisation of the Hybrid Schistosome Infecting Humans In Europe Reveals a Complex Admixture Between Schistosoma haematobium and Schistosoma bovis Parasites.

Kincaid-Smith, J.; Tracey, A.; de Carvalo Augusto, R.; Bulla, I.; Holroyd, N.; Rognon, A.; Rey, O.; Chaparro, C.; Oleaga, A.; Mas-Coma, S.; Allienne, J.-F.; Grunau, C.; Berriman, M.; Boissier, J.; Toulza, E.

10.1101/387969 — genomics — Posted on 2019-01-03

2896 Implantable electrical stimulation bioreactor with liquid crystal polymer based electrodes for enhanced bone regeneration at mandibular large defects in rabbit

Kim, C.; Yang, H. J.; Cho, T. H.; Lee, B.; Gwon, T. M.; Shin, S.; Kim, I. S.; Kim, S. J.; Hwang, S. J.

10.1101/402719 — bioengineering — Posted on 2019-01-03

2897 A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system

Burlion, A.; Ramos, R.; Sendeyo, K.; KC, P.; Corneau, A.; Caux, C.; Piaggio, E.; Olive, D.; Caux, C.; Marodon, G.

10.1101/191031 — immunology — Posted on 2019-01-03

2898 Redox signaling via lipid peroxidation regulates retinal progenitor cell differentiation

Albadri, S.; Naso, F.; Gauron, C.; Parolin, C.; Duroure, K.; Fiori, J.; Boga, C.; Vriz, S.; Calonghi, N.; Del Bene, F.

10.1101/510438 — developmental biology — Posted on 2019-01-03

2899 A novel small molecule screening platform for disrupting toxic tau oligomers in cells

Lo, C. H.; Lim, C. K.-W.; Ding, Z.; Wickramasinghe, S.; Braun, A. R.; Rhoades, E.; Thomas, D. D.; Sachs, J. N.

10.1101/510412 — neuroscience — Posted on 2019-01-03

2900 General visual and contingent thermal cues interact to elicit attraction in female Aedes aegypti mosquitoes

Liu, M. Z.; Vosshall, L. B.

10.1101/510594 — neuroscience — Posted on 2019-01-03

2901 Ephrin receptor A4 (EphA4) is a new Kaposi’s sarcoma-associated herpesvirus virus entry receptor

Chen, J.; Zhang, Z.; Schaller, S.; Jardetzky, T. S.; Longnecker, R.

10.1101/510651 — microbiology — Posted on 2019-01-03

2902 Polar-like trophoblast stem cells form an embryonic-abembryonic axis in blastoids.

Frias Aldeguer, J.; Kip, M.; Vivie, J.; Li, L.; Alemany Arias, A.; Korving, J.; Darmis, F.; van Blitterswijk, C.; van Oudenaarden, A.; Geijsen, N.; Rivron, N. C.

10.1101/510362 — developmental biology — Posted on 2019-01-03

2903 Differential expression of BMP antagonists, gremlin and noggin in hydra: antagonism between Wnt and BMP pathways

Krishnapati, L. S.; Khade, S.; Trimbake, D.; Patwardhan, R.; Nadimpalli, S. K.; Ghaskadbi, S.

10.1101/510602 — developmental biology — Posted on 2019-01-03

2904 Target-detecting neurons in the dragonfly lock on to selectively attended targets

Lancer, B. H.; Evans, B. J. E.; Fabian, J. M.; O'Carroll, D. C.; Wiederman, S. D.

10.1101/496562 — neuroscience — Posted on 2019-01-03

2905 Phylogenomics of the adaptive radiation of Triturus newts supports gradual ecological niche expansion towards an incrementally aquatic lifestyle

Wielstra, B.; McCartney-Melstad, E.; Arntzen, J. W.; Butlin, R. K.; Shaffer, H. B.

10.1101/463752 — evolutionary biology — Posted on 2019-01-02

2906 Tracking genetic invasions: genome-wide SNPs reveal the source of pyrethroid-resistant Aedes aegypti (yellow fever mosquito) incursions at international ports

Schmidt, T.; van Rooyen, A. R.; Chung, J.; Endersby-Harshman, N. M.; Griffin, P. C.; Sly, A.; Hoffmann, A. A.; Weeks, A. R.

10.1101/490714 — genomics — Posted on 2019-01-02

2907 Tau local structure shields amyloid motif and controls aggregation propensity

Chen, D.; Drombosky, K. W.; Hou, Z.; Sari, L.; Kashmer, O. M.; Ryder, B. D.; Perez, V. A.; Woodard, D. R.; Lin, M.; Diamond, M. I.; Joachimiak, L. A.

10.1101/330266 — biophysics — Posted on 2019-01-02

2908 Studying the dawn of de novo gene emergence in mice reveals fast integration of new genes into functional networks

Xie, C.; Bekpen, C.; Künzel, S.; Keshavarz, M.; Krebs-Wheaton, R.; Skrabar, N.; Ullrich, K. K.; Tautz, D.

10.1101/510214 — evolutionary biology — Posted on 2019-01-02

2909 Personalized Tumor Growth Prediction with Multiscale Tumor Modeling

Unsal, S.; Acar, A.; Itik, M.; Kabatas, A.; Gedikli, O.; Ozdemir, F.; Turhan, K.

10.1101/510172 — bioinformatics — Posted on 2019-01-02

2910 Enjoy The Violence: Is appreciation for extreme music the result of cognitive control over the threat response system?

Ollivier, R.; Goupil, L.; Liuni, M.; Aucouturier, J.-J.

10.1101/510008 — neuroscience — Posted on 2019-01-02

2911 Altering nuclear import in early Xenopus laevis embryos affects later development

Jevtic, P.; Levy, D. L.

10.1101/510313 — developmental biology — Posted on 2019-01-02

2912 Self-organization of post-implantation-like embryonic tissues from blastoids

Vrij, E. J.; Scholte Op Reimer, Y.; Frias Aldeguer, J.; Misteli Guerreiro, I.; Kind, J.; Koo, B.-K.; van Blitterswijk, C.; Rivron, N.

10.1101/510396 — developmental biology — Posted on 2019-01-02

2913 In vitro analysis of RNA polymerase II elongation complex dynamics

Joo, Y. J.; Ficarro, S. B.; Chun, Y.; Marto, J. A.; Buratowski, S.

10.1101/510206 — biochemistry — Posted on 2019-01-02

2914 Dynamic causal modeling for calcium imaging data reveals differential effective connectivity for sensory processing in a barrel cortical column

Jung, K.; Kang, J.; Chung, S.; Park, H.-J.

10.1101/509653 — neuroscience — Posted on 2019-01-02

2915 Left anterior temporal lobe is necessary for efficient lateralised processing of spoken word identity

Cope, T.; Shtyrov, Y.; MacGregor, L.; Holland, R.; Pulvermuller, F.; Rowe, J. B.; Patterson, K.

10.1101/510347 — neuroscience — Posted on 2019-01-02

2916 Spatial single-cell profiling of intracellular metabolomes in situ

Rappez, L.; Stadler, M.; Triana Sierra, S. H.; Phapale, P.; Heikenwalder, M.; Alexandrov, T.

10.1101/510222 — molecular biology — Posted on 2019-01-02

2917 Effects of partial, combined and total replacement of sodium chloride in beef sausage on microbial load, sensory acceptability and physical properties

Oshibanjo, O. D. O.; Odion, I. O.

10.1101/506071 — microbiology — Posted on 2019-01-02

2918 Noncanonical contributions of MutLγ to VDE-initiated crossovers during Saccharomyces cerevisiae meiosis

Shodhan, A.; Medhi, D.; Lichten, M.

10.1101/510297 — genetics — Posted on 2019-01-02

2919 Causes Of Death And Failures To Reproduce, Limiting Resources, Ecological Dynamics, And Selection: How To Evolve A Low Predation Guppy, And Cause A Trophic Cascade

Coulson, T.

10.1101/509067 — ecology — Posted on 2019-01-02

2920 Unbinding Kinetics and Multiple Pathways of p38 MAPK Inhibitors

Ge, X.; Tan, H.; Xie, L.

10.1101/510255 — pharmacology and toxicology — Posted on 2019-01-02

2921 Novel, non-nitrocatechol COMT inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

Byers, S.; Buchler, I. P.; DePasquale, M.; Rowley, H. L.; Kulkarni, R. S.; Pinder, L.; Kolobova, A.; Li, C.; Au, V.; Akuma, D.; Zhang, G.; Wei, H.; Cheetham, S. C.; Barrow, J. C.; Carr, G.

10.1101/510040 — neuroscience — Posted on 2019-01-02

2922 Modulation of tonotopic ventral MGB is behaviorally relevant for speech recognition.

Mihai, P. G.; Moerel, M.; de Martino, F.; Trampel, R.; Kiebel, S.; von Kriegstein, K.

10.1101/510164 — neuroscience — Posted on 2019-01-02

2923 Bacillus clarus sp. nov. is a new Bacillus cereus group species isolated from soil

Mendez Acevedo, M.; Carroll, L. M.; Mukherjee, M.; Mills, E.; XIaoli, L.; Dudley, E. G.; Kovac, J.

10.1101/508077 — microbiology — Posted on 2019-01-02

2924 Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion

Duc, C.; Yoth, M.; Mouniee, N.; Jensen, S.; Vaury, C.; Brasset, E.

10.1101/510016 — genetics — Posted on 2019-01-02

2925 Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson’s disease

Fava, V. M.; Xu, Y. Z.; Lettre, G.; Van Thuc, N.; Orlova, M.; Thai, V. H.; Cambri, G.; Tao, S.; Lahiri, R.; Adams, L.; Cobat, A.; Alcais, A.; Abel, L.; Schurr, E.

10.1101/507806 — genetics — Posted on 2019-01-02

2926 Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

Pearl, L. H.; Bigot, N.; Day, M.; Baldock, R. A.; Watts, F. Z.; Oliver, A.

10.1101/510032 — cell biology — Posted on 2019-01-02

2927 Organism-wide single-cell transcriptomics of long-lived C. elegans daf-2 mutants reveals tissue-specific reprogramming of gene expression networks

Preston, J.; Stiffler, N.; Weitzman, M.

10.1101/509992 — cell biology — Posted on 2019-01-02

2928 The influence of kinesthetic motor imagery and effector specificity on the long-latency stretch response

Forgaard, C.; Franks, I. M.; Maslovat, D.; Chua, R.

10.1101/510271 — neuroscience — Posted on 2019-01-02

2929 Evidence of a Functionally Segregated Pathway from Lateral Superior Olive to Inferior Colliculus

Greene, N. T.; Davis, K. A.

10.1101/510354 — neuroscience — Posted on 2019-01-02

2930 The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity

Jevtic, P.; Schibler, A. C.; Pegoraro, G.; Misteli, T.; Levy, D. L.

10.1101/510230 — cell biology — Posted on 2019-01-02

2931 Wheat VRN1 and FUL2 play critical and redundant roles in spikelet meristem identity and spike determinacy

Li, C.; Lin, H.; Chen, A.; Lau, M.; Jernstedt, J.; Dubcovsky, J.

10.1101/510388 — developmental biology — Posted on 2019-01-02

2932 SpliceV: Analysis and publication quality printing of linear and circular RNA splicing, expression and regulation.

Ungerleider, N. A.; Flemington, E. K.

10.1101/509661 — bioinformatics — Posted on 2019-01-02

2933 The most abundant cyst wall proteins of Acanthamoeba castellanii are three sets of lectins that bind cellulose and chitin and localize to distinct structures in cyst walls

Samuelson, J.; Magistrado-Coxen, P.; Aqeel, Y.; Lopez, A.; Haserick, J. R.; Urbanowicz, B. R.; Costello, C. E.

10.1101/496307 — microbiology — Posted on 2019-01-02

2934 Next-generation sequencing based hospital outbreak investigation yields insight into Klebsiella aerogenes population structure and determinants of carbapenem resistance and virulence

Malek, A.; McGlynn, K.; Taffner, S.; Fine, L.; Tesini, B.; Wang, J.; Mostafa, H. H.; Petry, S.; Perkins, A.; Graman, P.; Hardy, D. J.; Pecora, N. D.

10.1101/497958 — genomics — Posted on 2019-01-02

2935 Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma

Massey, S. C.; White, H.; Whitmire, P.; Doyle, T.; Johnston, S. K.; Singleton, K. W.; Jackson, P. R.; Hawkins-Daarud, A.; Bendok, B. R.; Porter, A. B.; Vora, S.; Sarkaria, J. N.; Mrugala, M. M.; Swanson, K. R.

10.1101/509281 — cancer biology — Posted on 2019-01-02

2936 HIV-1-induced cytokines deplete homeostatic ILCs and expand TCF7-dependent memory NK cells

Wang, Y.; Gellatly, K.; McCauley, S.; Vangala, P.; Kim, K.; Derr, A.; Jaiswal, S.; Kucukural, A.; McDonel, P.; Lifshitz, L.; Greenough, T.; Houghton, J.; Garber, M.; Luban, J.

10.1101/221010 — immunology — Posted on 2019-01-02

2937 Diet carbs versus fat: does it really matter for maintaining lost weight?

Hall, K. D.; Guo, J.

10.1101/476655 — physiology — Posted on 2019-01-02

2938 qDSB-Seq: quantitative DNA double-strand break sequencing

Zhu, Y.; Biernacka, A.; Pardo, B.; Dojer, N.; Forey, R.; Skrzypczak, M.; Fongang, B.; Nde Kengne, J. B.; Yousefi, R.; Pasero, P.; Ginalski, K.; Rowicka, M.

10.1101/171405 — genomics — Posted on 2019-01-02

2939 GRAM: A generalized model to predict the molecular effect of a non-coding variant in a cell-type specific manner

Lou, S.; Cotter, K. A.; Li, T.; Liang, J.; Mohsen, H.; Liu, J.; Zhang, J.; Cohen, S.; Xu, J.; Yu, H.; Rubin, M.; Gerstein, M.

10.1101/482992 — bioinformatics — Posted on 2019-01-02

2940 Loss of YAP/TAZ impaired the proliferation and differentiation ability of neural progenitor cells

Kong, S.; Rock, C. O.; Cao, X.

10.1101/296053 — neuroscience — Posted on 2019-01-02

2941 Neural processing of communication signals: The extent of sender-receiver matching varies across species of Apteronotus

Allen, K. M.; Marsat, G.

10.1101/387324 — neuroscience — Posted on 2019-01-02

2942 The function of macromolecular complex of CFTR-NHERF2-LPA2 in inflammatory responses of intestinal epithelial cells

Kong, S.; Zhang, W.

10.1101/186023 — pathology — Posted on 2019-01-02

2943 Inferring macro-ecological patterns from local species’ occurrences

Tovo, A.; Formentin, M.; Suweis, S.; Stivanello, S.; Azaele, S.; Maritan, A.

10.1101/387456 — ecology — Posted on 2019-01-02

2944 STAM Interaction with Hrs Controls JAK/STAT Activation by Interferon-α at the Early Endosome

Zanin, N.; Blouin, C. M.; Viaris de Lesegno, C.; Chmiest, D.; Johannes, L.; Lamaze, C.

10.1101/509968 — cell biology — Posted on 2019-01-02

2945 Remodeling of Mycobacterium tuberculosis lipids regulates prpCD during acid growth arrest

Baker, J. J.; Abramovitch, R. B.

10.1101/509570 — microbiology — Posted on 2019-01-02

2946 Exploring Frequency-dependent Brain Networks from ongoing EEG using Spatial ICA during music listening

Zhu, Y.; Zhang, C.; Toiviainen, P.; Huotilainen, M.; Mathiak, K.; Ristaniemi, T.; Cong, F.

10.1101/509802 — neuroscience — Posted on 2019-01-02

2947 High prevalence and diversity of Extended-Spectrum β-Lactamase and emergence of Carbapenemase producing Enterobacteriaceae spp in wildlife in Catalonia

Darwich, L.; Vidal, A.; Seminati, C.; Albamonte, A.; Casado, A.; Lopez, F.; Molina-Lopez, R. A.; Migura-Garcia, L.

10.1101/510123 — microbiology — Posted on 2019-01-02

2948 Computational Analysis of Insulin-Glucagon Signalling Network: Implications of Bistability in Metabolic Homeostasis and Disease states

Somvanshi, P. R.; Tomar, M.; Kareenhalli, V.

10.1101/509208 — systems biology — Posted on 2019-01-02

2949 A novel defective recombinant porcine enterovirus G virus carrying a porcine torovirus papain-like cysteine protease gene and a putative anti-apoptosis gene in place of viral structural protein genes

Imai, R.; Nagai, M.; Sakaguchi, S.; Masuda, T.; Kuroda, M.; Oba, M.; Katayama, Y.; Naoi, Y.; Tsuchiaka, S.; Omatsu, T.; Yamazato, H.; Makino, S.; Mizutani, T.

10.1101/510131 — microbiology — Posted on 2019-01-02

2950 The Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment with TNF-alpha Antagonist

Vaisman-Mentesh, A.; Rosenstein, S.; Yavzori, M.; Dror, Y.; Fudim, E.; Ungar, B.; Kopylov, U.; Picard, O.; Kigel, A.; Ben-Horin, S.; Benhar, I.; Wine, Y.

10.1101/509489 — immunology — Posted on 2019-01-02

2951 SpliceV: Analysis and publication quality printing of linear and circular RNA splicing, expression and regulation.

Ungerleider, N. A.; Flemington, E. K.

10.1101/509661 — bioinformatics — Posted on 2019-01-02

2952 Sensitivity analysis of agent-based simulation utilizing massively parallel computation and interactive data visualization

Niida, A.; Hasegawa, T.; Miyano, S.

10.1101/510057 — bioinformatics — Posted on 2019-01-02

2953 Integration of gut microbiome, host biomarkers, and urine metabolome data reveals networks of interactions associated with distinct clinical phenotypes

Li, R.-J.; Jie, Z.-Y.; Feng, Q.; Fang, R.-L.; Li, F.; Gao, Y.; Xia, H.-H.; Zhong, H.-Z.; Tong, B.; Xu, J.-Y.; Madsen, L.; Liu, C.-L.; Xu, Z.-G.; Wang, J.; Yang, H.-M.; Xu, X.; Hou, Y.; Brix, S.; Kristiansen, K.; Yu, X.-L.; Jia, H.-J.; He, K.-L.

10.1101/509703 — microbiology — Posted on 2019-01-02

2954 A 3-hydroxy-3-methylglutaryl-CoA synthase-based probe for the discovery of the acyltransferase-less type I polyketide synthases

Liang, H.; Jiang, L.; Jiang, Q.; Shi, J.; Xiang, J.; Yan, X.; Zhu, X.; Zhao, L.; Shen, B.; Duan, Y.; Huang, Y.

10.1101/509463 — microbiology — Posted on 2019-01-02

2955 Self-determination motivation theory in R: The software package SDT

Ünlü, A.

10.1101/510115 — scientific communication and education — Posted on 2019-01-02

2956 Fecal microbiota dysbiosis in macaques and humans within a shared environment

Grant, E.; Kyes, R. C.; Kyes, P.; Trinh, P.; Ramirez, V.; Tanee, T.; Pinlaor, P.; Dangtakot, R.; Rabinowitz, P. M.

10.1101/510065 — microbiology — Posted on 2019-01-02

2957 Birth-and-death evolution of the fatty acyl-CoA reductase (FAR) gene family and diversification of cuticular hydrocarbon synthesis in Drosophila

Finet, C.; Slavik, K.; Pu, J.; Carroll, S. B.; Chung, H.

10.1101/509588 — evolutionary biology — Posted on 2019-01-02

2958 Fanconi anemia proteins are required to maintain nucleolar homeostasis.

Gueiderikh, A.; Rouvet, G.; Souquere-Besse, S.; Apcher, S.; Diaz, J.-J.; Rosselli, F.

10.1101/509950 — cell biology — Posted on 2019-01-02

2959 Spatial organization of the transcriptional regulatory network of Saccharomyces cerevisiae

Sun, D.-Q.; Tian, L.; Ma, B.-G.

10.1101/509224 — systems biology — Posted on 2019-01-02

2960 Sensory feedback independent pre-song vocalizations correlate with current state of motor preparation

Rao, D.; Kojima, S.; Rajan, R.

10.1101/509505 — neuroscience — Posted on 2019-01-02

2961 Meta-analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics

Lee, H.-J.; Kremer, D. M.; Sajjakulnukit, P.; Zhang, L.; Lyssiotis, C. A.

10.1101/509372 — bioinformatics — Posted on 2019-01-02

2962 Spring-loaded inverted pendulum goes through two contraction-extension cycles during the single stance phase of walking

Antoniak, G.; Biswas, T.; Sikdar, S.; Cortes, N.; Chun, C.; Vikas, B.

10.1101/509687 — bioengineering — Posted on 2019-01-02

2963 History-dependent perturbation response in limb muscle

Libby, T.; Chukwueke, C.; Sponberg, S.

10.1101/509646 — physiology — Posted on 2019-01-02

2964 Disparate evolution of virus populations in upper and lower airways of mechanically ventilated patients

Koel, B. F.; van Someren Greve, F.; Vigeveno, R. M.; Pater, M.; Russell, C. A.; de Jong, M. D.

10.1101/509901 — microbiology — Posted on 2019-01-02

2965 Plasticity in evolutionary games

Dridi, S.

10.1101/509604 — evolutionary biology — Posted on 2019-01-02

2966 Base-pair mismatch can destabilize small DNA loops through cooperative kinking

Jeong, J.; Kim, H.

10.1101/509711 — biophysics — Posted on 2019-01-02

2967 MetaDome: Pathogenicity analysis of genetic variants through aggregation of homologous human protein domains

Wiel, L.; Baakman, C.; Gilissen, D.; Veltman, J. A.; Vriend, G.; Gilissen, C.

10.1101/509935 — bioinformatics — Posted on 2019-01-02

2968 BioSAILs: versatile workflow management for high-throughput data analysis

Rowe, J.; Drou, N.; Yousif, A.; Gunsalus, K.

10.1101/509455 — bioinformatics — Posted on 2019-01-02

2969 Detecting Circular RNA from High-throughput Sequence Data with de Bruijn Graph

Li, X.; Wu, Y.

10.1101/509422 — bioinformatics — Posted on 2019-01-02

2970 BjuWRR1, a CC-NB-LRR gene identified in Brassica juncea, confers resistance to white rust caused by Albugo candida

Arora, H.; Padmaja, K. L.; Paritosh, K.; Mukhi, N.; Tewari, A. K.; Mukhopadhyay, A.; Gupta, V.; Pradhan, A. K.; Pental, D.

10.1101/509851 — plant biology — Posted on 2019-01-02

2971 Turning mechanics of the bipedal hopping Desert kangaroo rat (Dipodomys deserti).

Collins, C. E.; McGowan, C. P.

10.1101/509398 — physiology — Posted on 2019-01-02

2972 Context-specific modulation of intrinsic coupling modes shapes multisensory processing

Galindo Leon, E. E.; Stitt, I.; Pieper, F.; Fiedler, E.; Stieglitz, T.; Engler, G.; Engel, A. K.

10.1101/509943 — neuroscience — Posted on 2019-01-02

2973 Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma

Carow, B.; Hauling, T.; Qian, X.; Kramnik, I.; Nilsson, M.; Rottenberg, M. E.

10.1101/509547 — immunology — Posted on 2019-01-02

2974 Locally Fixed Alleles: A method to localize gene drive to island populations

Sudweeks, J.; Hollingsworth, B.; Blondel, D. V.; Campbell, K. J.; Dhole, S.; Eisemann, J. D.; Edwards, O.; Godwin, J.; Howald, G. R.; Oh, K.; Piaggio, A. J.; Prowse, T. A. A.; Ross, J. V.; Saah, J. R.; Shiels, A. B.; Thomas, P.; Threadgill, D. W.; Vella, M. R.; Gould, F.; Lloyd, A.

10.1101/509364 — evolutionary biology — Posted on 2019-01-02

2975 A pseudo-meiotic centrosomal function of TEX12 in cancer

Sandhu, S.; Salmon, L. J.; Hunter, J. E.; Wilson, C. L.; Perkins, N. D.; Hunter, N.; Davies, O. R.; McClurg, U. L.

10.1101/509869 — cell biology — Posted on 2019-01-02

2976 Identifying multiple kinetic populations of DNA binding proteins in live cells using single-molecule fluorescence imaging

Ho, H. N.; Zalami, D.; Köhler, J.; van Oijen, A. M.; Ghodke, H.

10.1101/509620 — biophysics — Posted on 2019-01-02

2977 Knock-knock, who’s there: Sex-coding, competition and the energetics of tapping communication in the tok-tok beetle, Psammodes striatus (Coleoptera: Tenebrionidae)

Lighton, J. R. B.

10.1101/509257 — animal behavior and cognition — Posted on 2019-01-02

2978 Proximate causes and consequences of intergenerational influences of salient sensory experience.

Aoued, H. S.; Sannigrahi, S.; Hunter, S. C.; Doshi, N.; Chan, A.; Walum, H.; Dias, B. G.

10.1101/509596 — zoology — Posted on 2019-01-02

2979 Increased signal diversity/complexity of spontaneous EEG in humans given sub-anaesthetic doses of ketamine

Farnes, N.; Juel, B. E.; Nilsen, A. S.; Romundstad, L.; Storm, J. F.

10.1101/508697 — neuroscience — Posted on 2019-01-02

2980 Cognitive vulnerability to sleep deprivation is robustly associated with two dynamic connectivity states

Teng, J.; Ong, J. L.; Patanaik, A.; Tandi, J.; Chee, M. W. L.; Lim, J.

10.1101/509745 — neuroscience — Posted on 2019-01-02

2981 Early-generated interneurons regulate neuronal circuit formation during early postnatal development

Wang, C.-Z.; Ma, J.; Jiang, S.-N.; Chen, T.-Q.; Xu, Y.-Q.; Yuan, Z.-L.; Mao, X.-Y.; Zhang, S.-Q.; Liu, L.-Y.; Fu, Y.; Yu, Y.-C.

10.1101/509844 — neuroscience — Posted on 2019-01-02

2982 The virome in adult monozygotic twins with concordant or discordant gut microbiomes

Moreno-Gallego, J. L.; Chou, S.-P.; Di Rienzi, S. C.; Goodrich, J. K.; Spector, T.; Bell, J. T.; Youngblut, N.; Hewson, I.; Reyes, A.; Ley, R. E.

10.1101/509273 — microbiology — Posted on 2019-01-02

2983 Chandipura virus requires pro-survival RelA NF-κB function for its propagation

Bais, S. S.; Ratra, Y.; Kushawaha, P. K.; Basak, S.

10.1101/509893 — immunology — Posted on 2019-01-02

2984 Protein Fold Determination by Assembling Extended Super-Secondary Structure Motifs Using Limited NMR Data

Pilla, K. B.

10.1101/509356 — biophysics — Posted on 2019-01-02

2985 The green autofluorescence intensity and asymmetry of older men is significantly higher than those of older women in their fingernails and certain regions of skin

Tao, Y.; Zhang, M.; Wu, D.; Li, Y.; Ying, W.

10.1101/509562 — biophysics — Posted on 2019-01-02

2986 Disentangling sRNA-Seq data to study RNA communication between species

Bermudez-Barrientos, J. R.; Ramirez-Sanchez, O.; Chow, F. W.; Buck, A. H.; Abreu-Goodger, C.

10.1101/508937 — bioinformatics — Posted on 2019-01-02

2987 Corpus Colossal: A Bibliometric Analysis of Neuroscience Abstracts and Impact Factor

Kenkel, W.

10.1101/505057 — scientific communication and education — Posted on 2019-01-02

2988 The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease

van Rijn, A. L.; van Boheemen, S.; Carbo, E. C.; Pappas, N.; Sidorov, I.; Mei, H.; Aanerud, M.; Bakke, P.; Claas, E. C. J.; Eagan, T. M.; Hiemstra, P. S.; Kroes, A. C. M.; de Vries, J. J. C.

10.1101/509919 — microbiology — Posted on 2019-01-02

2989 Genetic interactions of histone acetyl-transferase enzymes encoding genes Gcn5 and Mof with hsrω lncRNA gene

Chaturvedi, D. P.

10.1101/509737 — genetics — Posted on 2019-01-02

2990 Antagonistic coevolution between multiple quantitative traits: matching interactions can be subsets of difference interactions

Yamamichi, M.; Lyberger, K.; Patel, S.

10.1101/509885 — evolutionary biology — Posted on 2019-01-02

2991 Cyclin F-Chk1 synthetic lethality mediated by E2F1 degradation

D'Angiolella, V.; Yang, H.; Faedda, R.; Hume, S.; Ebner, D.; Hatch, S. B.; Kessler, B.; Burdova, K.; Vendrell, I.; Drewry, D. H.; Wells, C. I.

10.1101/509810 — cancer biology — Posted on 2019-01-02

2992 Does the heart forget? Modulation of cardiac activity induced by inhibitory control over emotional memories

Legrand, N.; Etard, O.; Vandevelde, A.; Pierre, M.; Viader, F.; Clochon, P.; Doidy, F.; Peschanski, D.; Eustache, F.; Gagnepain, P.

10.1101/376954 — neuroscience — Posted on 2019-01-02

2993 Everyday taxi drivers: Do better navigators have larger hippocampi?

Weisberg, S. M.; Newcombe, N. S.; Chatterjee, A.

10.1101/431155 — neuroscience — Posted on 2019-01-02

2994 Trichoderma asperelloides enhances local (LAR) and systemic acquired resistance (SAR) response under low nitrate nutrition in Arabidopsis

Wany, A.; Pathak, P. K.; Gupta, K. J.

10.1101/502492 — plant biology — Posted on 2019-01-02

2995 Solving the riddle of the evolution of Shine-Dalgarno based translation in chloroplasts

Weiner, I.; Shahar, N.; Marcu, P.; Yacoby, I.; Tuller, T.

10.1101/440842 — plant biology — Posted on 2019-01-02

2996 Genome sequence of Pseudomonas aeruginosa PAO1161, a PAO1 derivative with the ICEPae1161 integrative and conjugative element

Kawalek, A.; Kotecka, K.; Modrzejewska, M.; Jagura-Burdzy, G.; Bartosik, A. A.

10.1101/494302 — microbiology — Posted on 2019-01-02

2997 Climatic limits for the present European distribution of hornbeam (Carpinus betulus), with special reference to Ukraine

Tytar, V.

10.1101/506428 — ecology — Posted on 2019-01-02

2998 Species-specific strategies increase unpredictability of escape flight in eared moths

Huegel, T.; Goerlitz, H. R.

10.1101/485698 — animal behavior and cognition — Posted on 2019-01-02

2999 Intra-individual methylomics detects the impact of early-life adversity

Jiang, S.; Kamei, N.; Bolton, J. L.; Ma, X.; Stern, H. S.; Baram, T. Z.; Mortazavi, A.

10.1101/440503 — genomics — Posted on 2019-01-02

3000 Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma

10.1101/509281 — cell biology — Posted on 2019-01-02

3001 Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines, and tissue samples

Streit, M.; Gratzl, S.; Stitz, H.; Wernitznig, A.; Zichner, T.; Haslinger, C.

10.1101/277848 — bioinformatics — Posted on 2019-01-02

3002 Kinetic Analysis of Bacteriophage Sf6 Binding to Outer Membrane Protein A Using Whole Virions

Hubbs, N. B.; Whisby-Pitts, M. M.; McMurry, J. L.

10.1101/509141 — microbiology — Posted on 2019-01-02

3003 Different integrins mediate haptotaxis of T lymphocytes towards either lower or higher adhesion zones

Luo, X.; Aoun, L.; Biarnes-Pelicot, M.; Strale, P.-O.; Studer, V.; Valignat, M.-P.; Theodoly, O.

10.1101/509240 — biophysics — Posted on 2019-01-02

3004 Nano-enhanced optical gene delivery to retinal degenerated mice

Batabyal, S.; Gajjeraman, S.; Bhattacharya, S.; Wright, W.; Mohanty, S.

10.1101/509349 — bioengineering — Posted on 2019-01-02

3005 Simultaneous proteomics and three PTMomics characterization of pro-inflammatory cytokines stimulated INS-1E cells using TiO2 enrichment strategy

Huang, H.; Drici, L.; Lassen, P.; Palmisano, G.; Larsen, M. R.

10.1101/509125 — biochemistry — Posted on 2019-01-02

3006 Differential regulation of native and learned behavior by creb1/crh-1 in Caenorhabditis elegans

Dahiya, Y.; Rose, S.; Thapliyal, S.; Bhardwaj, S.; Prasad, M.; Babu, K.

10.1101/508986 — neuroscience — Posted on 2019-01-02

3007 Scarless whole-body regeneration in the absence of a blastema requires cell division in the ctenophore Mnemiopsis leidyi.

Mateu, J. R.; martindale, m. q.

10.1101/509331 — developmental biology — Posted on 2019-01-02

3008 Intermittent hormonal therapy shows similar outcome than SOC in ER+ breast cancer preclinical model.

Enriquez Navas, P. M.; Garcia, L.; Abdalah, M.; Stringfield, O.; Luddy, K.; Hassan, S.; Gillies, R. J.; Gatenby, R. A.

10.1101/509158 — cancer biology — Posted on 2019-01-02

3009 Mammalian Amoeboid Swimming is propelled by molecular and not protrusion-based paddling in Lymphocytes

Aoun, L.; Negre, P.; Farutin, A.; Garcia-Seyda, N.; Rivzi, M. S.; Galland, R.; Michelot, A.; Luo, X.; Biarnes-Pelicot, M.; Hivroz, C.; Rafai, S.; Sibareta, J.-B.; Valignat, M.-P.; Misbah, C.; Theodoly, O.

10.1101/509182 — biophysics — Posted on 2019-01-02

3010 Effect of Adhesion and Substrate Elasticity on Neutrophil Extracellular Trap Formation

Erpenbeck, L.; Gruhn, A. L.; Kudryasheva, G.; Guenay, G.; Meyer, D.; Neubert, E.; Grandke, J.; Schoen, M. P.; Rehfeldt, F.; Kruss, S.

10.1101/508366 — biophysics — Posted on 2019-01-02

3011 Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A

Goebl, C.; Morris, V.; van Dam, L.; Visscher, M.; Polderman, P.; Hartlmueller, C.; de Ruiter, H.; Hora, M.; Liesinger, L.; Birner-Gruenberger, R.; Vos, H.; Reif, B.; Madl, T.; Dansen, T.

10.1101/509109 — biochemistry — Posted on 2019-01-02

3012 Secretion of an Argonaute protein by a parasitic nematode and the evolution of its siRNA guides

Chow, F. W.-N.; Koutsovoulos, G.; Ovando-Vazquez, C.; Neophytou, K.; Laetsch, D. R.; Bermudez-Barrientos, J. R.; Kumar, S.; Robertson, E.; Claycomb, J. M.; Blaxter, M.; Abreu-Goodger, C.; Buck, A. H.