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Archive, 2023-11

3 Safety Assessment of Intravenous Injection of Rat Embryonic Proteome Extract for in-vivo Regenerative Therapies
DARSI, S. R. P.; Kandula, S. k.; barani, K. K.; Pasupulati, A. K.; chikatla, s. s.; Darsi, S. K.; Kamireddy, A. R.; Barra, R. R.; Devarasetty, A. K.; Surampudi, S.
10.1101/2023.10.30.563384 — developmental biology — Posted on 2023-11-30
7 Puromycin reveals a distinct conformation of neuronal ribosomes
Anadolu, M. N.; Sun, J.; Li, J. T.-Y.; Graber, T.; Ortega, J.; Sossin, W. S.
10.1101/2023.05.02.539124 — neuroscience — Posted on 2023-11-30
11 Unlocking the Role of sMyBP-C: A Key Player in Skeletal Muscle Development and Growth
Song, T.; McNamara, J.; Baby, A.; Ma, W.; Landim-Vieira, M.; Natesan, S.; Pinto, J. R.; Lorenz, J. N.; Irving, T.; Sadayappan, S.
10.1101/2023.10.23.563591 — physiology — Posted on 2023-11-30
16 Recruitment of FBXO22 for Targeted Degradation of NSD2
Nie, D. Y.; Tabor, J. R.; Li, J.; Kutera, M.; St-Germain, J.; Hanley, R. P.; WOLF, E. Z.; Paulakonis, E.; Kenney, T. M. G.; Duan, S.; Shrestha, S.; Owens, D. D.; Pon, A.; Szewczyk, M.; Lamberto, A. J.; Menes, M.; Li, F.; Barsyte-Lovejoy, D.; Brown, N. G.; Barsotti, A. M.; Stamford, A. W.; Collins, J. L.; Wilson, D. J.; Raught, B.; Licht, J.; James, L.; Arrowsmith, C.
10.1101/2023.11.01.564830 — biochemistry — Posted on 2023-11-30
17 A super-pangenome of the North American wild grape species
Cochetel, N.; Minio, A.; Guarracino, A.; Garcia, J. F.; Figueroa-Balderas, R.; Massonnet, M.; Londo, J.; Garrison, E.; Gaut, B.; Cantu, D.
10.1101/2023.06.27.545624 — genomics — Posted on 2023-11-30
21 The Heritability of Human Connectomes: a Causal Modeling Analysis
Chung, J.; Bridgeford, E. W.; Powell, M.; Pisner, D.; Xu, T.; Vogelstein, J. T.
10.1101/2023.04.02.532875 — neuroscience — Posted on 2023-11-30
22 Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1
Kılıc, A.; Halu, A.; De Marzio, M.; Maiorino, E.; Duvall, M. G.; Brüggemann, T. R.; Rojas Quintero, J. J.; Chase, R.; Mirzakhani, H.; Özge Sungur, A.; Koepke, J.; Nakano, T.; Peh, H. Y.; Krishnamoorthy, N.; Abdulnour, R.-E.; Georgopoulos, K.; Litonjua, A. A.; Demay, M. B.; Renz, H.; Levy, B. D.; Weiss, S. T.
10.1101/2022.05.22.491886 — systems biology — Posted on 2023-11-30
25 Parallel evolution and enhanced virulence upon in vivo passage of an RNA virus in Drosophila melanogaster
Lezcano, O. M.; Fuhrmann, L.; Ramakrishnan, G.; Beerenwinkel, N.; Huynen, M.; van Rij, R. P.
10.1101/2023.07.21.549997 — microbiology — Posted on 2023-11-30
26 Distinct disease-modifying therapies are associated with different blood immune cell profiles in people with relapsing-remitting multiple sclerosis
Canto-Gomes, J.; Boleixa, D.; Teixeira, C.; Martins da Silva, A.; Gonzalez-Suarez, I.; Cerqueira, J. J.; Correia-Neves, M.; Nobrega, C.
10.1101/2023.07.20.549852 — immunology — Posted on 2023-11-30
27 Aperiodic component of EEG power spectrum and cognitive performance in aging: the role of education
Montemurro, S.; Borek, D.; Marinazzo, D.; Zago, S.; Masina, F.; Napoli, E.; Filippini, N.; Arcara, G.
10.1101/2023.10.05.560988 — neuroscience — Posted on 2023-11-30
28 Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1 transcription signature
Shen, D.; Vincent, A.; Udine, E.; Buhidma, Y.; Anoar, S.; Tsintzas, E.; Maeland, M.; Rademakers, R.; Isaacs, A.; Frigerio, C. S.; van Blitterswijk, M.; Lashley, T.; Niccoli, T.
10.1101/2023.11.20.567861 — neuroscience — Posted on 2023-11-30
30 The spatial landscape of Cancer Hallmarks reveals patterns of tumor ecology
Sibai, M.; Cervilla, S.; Grases, D.; Musulen, E.; Lazcano, R.; Mo, C.-K.; Davalos, V.; Fortian, A.; Romeo, M.; Bernat, A.; Tokheim, C.; Grande, E.; Real, F.; Barretina, J.; Lazar, A.; Ding, L.; Esteller, M.; Bailey, M.; Porta-Pardo, E.
10.1101/2022.06.18.496114 — cancer biology — Posted on 2023-11-30
33 A targeted metabolomic method to detect epigenetically relevant metabolites
Miro-Blanch, J.; Junza, A.; Capellades, J.; Balvay, A.; Moudet, C.; Kovatcheva, M.; Raineri, S.; Rabot, S.; Mellor, J.; Serrano, M.; Yanes, O.
10.1101/2023.11.30.569455 — biochemistry — Posted on 2023-11-30
34 ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages
Bates, T. A.; Trank-Greene, M.; Nguyenla, X.; Anastas, A.; Gurmessa, S.; Merutka, I. R.; Dixon, S. D.; Shumate, A.; Groncki, A. R.; Parson, M. A.; Ingram, J. R.; Barklis, E.; Burke, J. E.; Shinde, U.; Ploegh, H. L.; Tafesse, F. G.
10.1101/2023.08.16.553641 — biochemistry — Posted on 2023-11-30
35 Phosphogluconolactonase as the linchpin of an efficient pentose phosphate pathway
Phegnon, L.; Perochon, J.; Uttenweiler-Joseph, S.; Cahoreau, E.; Millard, P.; Letisse, F.
10.1101/2023.11.29.569206 — biochemistry — Posted on 2023-11-30
36 Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
Gaur, P.; Rajendran, Y.; Srivastava, B.; Markandey, M.; Fishbain-Yoskovitz, V.; Mohapatra, G.; Suhail, A.; Chaudhary, S.; Tyagi, S.; Yadav, S. C.; Pandey, A. K.; Merbl, Y.; Bajaj, A.; Ahuja, V.; Srikanth, C.
10.1101/2023.02.13.528320 — cell biology — Posted on 2023-11-30
37 Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
Yu, V.; Yong, F.; Marta, A.; Khadayate, S.; Osakwe, A.; Bhattacharya, S.; Varghese, S. S.; Chabosseau, P.; Tabibi, S. M.; Chen, K.; Georgiadou, E.; Parveen, N.; Suleiman, M.; Stamoulis, Z.; Marselli, L.; De Luca, C.; Tesi, M.; Ostinelli, G.; Delgadillo-Silva, L.; Wu, X.; Hatanaka, Y.; Montoya, A.; Elliott, J.; Patel, B.; Demchenko, N.; Whilding, C.; Hajkova, P.; Schliaha, P.; Kramer, H.; Ali, Y.; Marchetti, P.; Sladek, R.; Dhawan, S.; Withers, D. J.; Rutter, G. A.; Millership, S. J.
10.1101/2023.02.04.527050 — cell biology — Posted on 2023-11-30
40 Emergence of RNA-guided transcription factors via domestication of transposon-encoded TnpB nucleases
Wiegand, T.; Hoffmann, F. T.; Walker, M. W. G.; Tang, S.; Richard, E.; Le, H. C.; Meers, C.; Sternberg, S. H.
10.1101/2023.11.30.569447 — genetics — Posted on 2023-11-30
41 Alternative Polyadenylation Determines the Functional Landscape of Inverted Alu Repeats
Ku, J.; Kim, S.; Lee, K.; Ku, D.; Kim, N.; Do, H.; Lee, H.; Han, J.; Lee, Y.-s.; Kim, Y.
10.1101/2023.11.30.569399 — molecular biology — Posted on 2023-11-30
43 Barcode 100K Specimens: In a Single Nanopore Run
Hebert, P. D. N.; Floyd, R.; Jafarpour, S.; Prosser, S. W. J.
10.1101/2023.11.29.569282 — molecular biology — Posted on 2023-11-30
44 The hydrogen isotope signatures of autotrophy versus heterotrophy recorded in archaeal tetraether lipids
Rhim, J. H.; Kopf, S.; McFarlin, J.; Batther, H.; Harris, C. M.; Zhou, A.; Feng, X.; Weber, Y.; Hoeft-McCann, S.; Pearson, A.; Leavitt, W. D.
10.1101/2023.11.29.569324 — microbiology — Posted on 2023-11-30
50 Gut Microbiome Dynamics and Predictive Value in Hospitalized COVID-19 Patients: A Comparative Analysis of Shallow and Deep Shotgun Sequencing
Kopera, K.; Gromowski, T.; Wydmanski, W.; Skonieczna-Zydecka, K.; Muszynska, A.; Zielinska, K.; Wierzbicka-Wos, A.; Kaczmarczyk, M.; Kadaj-Lipka, R.; Cembrowska-Lech, D.; Januszkiewicz, K.; Koftis, K.; Witkiewicz, W.; Nalewajska, M.; Feret, W.; Marlicz, W.; Labaj, P. P.; Rydzewska, G.; Kosciolek, T.
10.1101/2023.11.29.568526 — bioinformatics — Posted on 2023-11-30
51 Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction
Sokolova, V.; Miratsky, J.; Svetlov, V.; Brenowitz, M.; Vant, J.; Lewis, T. S.; Dryden, K.; Lee, G. L.; Sarkar, S. L.; Nudler, E.; Singharoy, A.; Tan, D.
10.1101/2023.11.30.569387 — biochemistry — Posted on 2023-11-30
52 Differences in clamp loader mechanism between bacteria and eukaryotes
Landeck, J. T.; Pajak, J.; Norman, E. K.; Sedivy, E. L.; Kelch, B. A.
10.1101/2023.11.30.569468 — biochemistry — Posted on 2023-11-30
54 Rho and a riboswitch regulate mntP expression evading manganese stress and membrane toxicity
Prakash, A.; Kalita, A.; Bhardwaj, K.; Mishra, R. K.; Ghose, D.; Kaur, G.; Pani, B.; Nudler, E.; Dutta, D.
10.1101/2023.11.29.566114 — biochemistry — Posted on 2023-11-30
57 SARS-CoV-2 NSP13 suppresses the Hippo pathway downstream effector YAP
Meng, F.; Kim, J. H.; Tsai, C.-R.; Wang, J.; Shi, Y.; Deshmukh, V.; Li, X.; Steimle, J.; Xie, B.; Li, R. G.; Martin, J.
10.1101/2023.11.30.569413 — cell biology — Posted on 2023-11-30
58 Natural and age-related variation in circulating human hematopoietic stem cells
Furer, N.; Rappoport, N.; Lifshitz, A.; bercovich, A.; Ben-Kiki, O.; Danin, A.; Kedmi, M.; Shipony, Z.; Lipson, D.; Meiri, E.; Yanai, G.; Shapira, S.; Arber, N.; Berdichevsky, S.; Tavor, S.; Tyner, J.; Joshi, S. K.; Landau, D.; Ganesan, S.; Dusaj, N.; Chamely, P.; Kaushansky, N.; Chapal Ilani, N.; Shamir, R.; Tanay, A.; Shlush, L.
10.1101/2023.11.30.569167 — molecular biology — Posted on 2023-11-30
60 Pre-mRNA fate decision safeguards the fidelity of the inflammatory response
Bestehorn, A. M.; Fesselet, J. A. M.; Didusch, S.; Zeiler, C.; Doppelmayer, K.; Borroni, M.; Le Heron, A.; Pfanzagl, V.; Chen, W.; Scinicariello, S.; Baccarini, M.; Versteeg, G. A.; Hartl, M.; Kovarik, P.
10.1101/2023.11.30.569392 — molecular biology — Posted on 2023-11-30
62 Antiviral humoral immunity against SARS-CoV-2 Omicron subvariants induced by XBB.1.5 monovalent vaccine in infection-naive and XBB-infected individuals
Kosugi, Y.; Kaku, Y.; Hinay, A. A.; Guo, Z.; Uriu, K.; Kihara, M.; Saito, F.; Uwamino, Y.; Kuramochi, J.; Shirakawa, K.; Takaori-Kondo, A.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Sato, K.
10.1101/2023.11.29.569330 — microbiology — Posted on 2023-11-30
64 Pollutome complexity determines the removal of recalcitrant pharmaceuticals
Suleiman, M.; Le Lay, N.; Demaria, F.; Kolvenbach, B. A.; Cretoiu, M. S.; Petchey, O. L.; Jousset, A.; Corvini, P. F.-X.
10.1101/2023.11.30.568980 — microbiology — Posted on 2023-11-30
67 A multi-strategy antimicrobial discovery approach reveals new ways to combat Chlamydia
Ölander, M.; Rea Vazquez, D.; Meier, K.; Mooij, L.; Fredlund, J.; Puertolas-Balint, F.; Calpe, E.; Diaz, M. R.; van der Wal, K.; Schroeder, B. O.; Sixt, B. S.
10.1101/2023.11.30.569351 — microbiology — Posted on 2023-11-30
68 An unusual two-strain cholera outbreak in Lebanon, 2022-2023: a genomic epidemiology study
Abou Fayad, A.; Rafei, R.; Njamkepo, E.; Ezzeddine, J.; Hussein, H.; Sinno, S.; Gerges, J.-R.; Barada, S.; Sleiman, A.; Assi, M.; Baakliny, M.; Hamedeh, L.; Mahfouz, R.; Dabboussi, F.; Feghali, R.; Mohsen, Z.; Rady, A.; Ghosn, N.; Abiad, F.; Abubakar, A.; Barakat, A.; Wauquier, N.; Quilici, M.-L.; Weill, F.-X.; Hamze, M.; Matar, G. M.
10.1101/2023.11.29.569232 — microbiology — Posted on 2023-11-30
70 metaExpertPro: a computational workflow for metaproteomics spectral library construction and data-independent acquisition mass spectrometry data analysis
Sun, Y.; Xing, Z.; Liang, S.; Miao, Z.; Zhuo, L.-b.; Jiang, W.; Zhao, H.; Gao, H.; Xie, Y.; Zhou, Y.; Yue, L.; Cai, X.; Chen, Y.-m.; Zheng, J.-S.; Guo, T.
10.1101/2023.11.29.569331 — microbiology — Posted on 2023-11-30
71 Persistent immune imprinting after XBB.1.5 COVID vaccination in humans
Tortorici, M. A.; Addetia, A.; Seo, A. J.; Brown, J.; Sprouse, K.; Logue, J.; Clarke, E.; Franko, N.; Chu, H.; Veesler, D.
10.1101/2023.11.28.569129 — immunology — Posted on 2023-11-30
76 Fibroblast-derived IL-11 is a driver and therapeutic target in Peutz-Jeghers syndrome polyposis
Domenech-Moreno, E.; Lim, W.-W.; Brandt, A.; Lemmetyinen, T.; Viitala, E.; Makela, T. P.; Cook, S.; Ollila, S.
10.1101/2023.11.29.568817 — cancer biology — Posted on 2023-11-30
77 JUN mediates senescence and immune cell recruitment to prevent prostate cancer progression
Redmer, T.; Raigel, M.; Sternberg, C.; Ziegler, R.; Probst, C.; Lindner, D.; Aufinger, A.; Limberger, T.; Trachtova, K.; Kodajova, P.; Hoegler, S.; Schlederer, M.; Stoiber, S.; Oberhuber, M.; Bolis, M.; Neubauer, H. A.; Miranda, S.; Tomberger, M.; Harbusch, N. S.; Garces de los Fayos Alonso, I.; Sternberg, F.; Moriggl, R.; Theurillat, J.-P.; Tichy, B.; Bystry, V.; Persson, J. L.; Mathas, S.; Aberger, F.; Strobl, B.; Pospisilova, S.; Merkel, O.; Egger, G.; Lagger, S.; Kenner, L.
10.1101/2023.11.29.569178 — cancer biology — Posted on 2023-11-30
78 Mechanistic insights into ligand dissociation from the SARS-CoV-2 spike glycoprotein
Hasse, T. A.; Mantei, E.; Shahoei, R.; Pawnikar, S.; Wang, J.; Miao, Y.; Huang, Y.-m. M.
10.1101/2023.11.29.569184 — biophysics — Posted on 2023-11-30
80 Precision sampling of discrete sites identified during in-vivo functional testing in the mammalian heart
Vermoortele, D.; Olianti, C.; Amoni, M.; Giardini, F.; De Buck, S.; Nagaraju, C. K.; Willems, R.; Roderick, L.; Sipido, K.; Sacconi, L.; Claus, P.
10.1101/2023.11.29.569166 — bioengineering — Posted on 2023-11-30
82 Development of a Nanoparticle-Based Tendon-Targeting Drug Delivery System to Pharmacologically Modulate Tendon Healing
Adjei-Sowah, E. E.; Chandrasiri, I.; Xiao, B.; Liu, Y.; Ackerman, J.; Soto, C.; Nichols, A. E.; Nolan, K.; Benoit, D. S. W.; Loiselle, A. E.
10.1101/2023.11.29.569204 — bioengineering — Posted on 2023-11-30
83 Gene expression shifts in Emperor penguin adaptation to the extreme Antarctic environment
Paris, J. R.; Fernandes, F. A. N.; Pirri, F.; Greco, S.; Gerdol, M.; Pallavicini, A.; Benoiste, M.; Cornec, C.; Zane, L.; Haas, B.; Le Bohec, C.; Trucchi, E.
10.1101/2023.11.29.569211 — evolutionary biology — Posted on 2023-11-30
84 Expanded Expression of Pro-Neurogenic Factor SoxB1 during Larval Development of gastropod Lymnaea stagnalis Suggests Preadaptation to Prolonged Neurogenesis in Mollusca
Kurtova, A. I.; Finoshin, A. D.; Aparina, M. S.; Gazizova, G. R.; Kozlova, O. S.; Voronova, S. N.; Shagimardanova, E. I.; Voronezhskaya, E. E.; Ivashkin, E. G.
10.1101/2023.11.29.569209 — developmental biology — Posted on 2023-11-30
85 OCA-B promotes autoimmune demyelination through control of stem-like CD4+ T cells
Hughes, E. P.; Syage, A. R.; Mehrabad, E. M.; Lane, T. E.; Spike, B. T.; Tantin, D.
10.1101/2023.11.29.569210 — immunology — Posted on 2023-11-30
89 Dissociating the reinforcing and sensory properties of medial accumbens shell dopamine.
Valyear, M. D.; Eustachon, N. M.-L.; Alymova, I.; Tremblay, B. N.; Mitrikeski, N. M.; Britt, J. P.
10.1101/2023.11.29.569116 — neuroscience — Posted on 2023-11-30
97 Parsing digital or analogue TCR performance through piconewton forces
Akitsu, A.; Kobayashi, E.; Feng, Y.; Stephens, H. M.; Brazin, K. N.; Masi, D. J.; Kirpatrick, E. H.; Mallis, R. J.; Duke-Cohan, J. S.; Booker, M. A.; Cinella, V.; Feng, W. W.; Holliday, E. L.; Lee, J. J.; Zienkiewicz, K. J.; Tolstorukov, M. Y.; Hwang, W. S.; Lang, M. J.; Reinherz, E.
10.1101/2023.11.29.568292 — immunology — Posted on 2023-11-30
98 Muscle contractile properties directly influence shared synaptic inputs to spinal motor neurons
Cabral, H. V.; Inglis, J. G.; Cudicio, A.; Cogliati, M.; Orizio, C.; Yavuz, U.; Negro, F.
10.1101/2023.11.30.569389 — neuroscience — Posted on 2023-11-30
101 Connectomic reconstruction predicts the functional organization of visual inputs to the navigation center of the Drosophila brain
Garner, D.; Kind, E.; Nern, A.; Houghton, L.; Zhao, A.; Sancer, G.; Rubin, G. M.; Wernet, M. F.; Kim, S. S.
10.1101/2023.11.29.569241 — neuroscience — Posted on 2023-11-30
103 Loss of Slc35a2 alters development of the mouse cerebral cortex
Elziny, S.; Sran, S.; Yoon, H.; Corrigan, R. R.; Page, J.; Ringland, A.; Lanier, A.; Lapidus, S.; Foreman, J.; Heinzen, E. L.; Iffland, P.; Crino, P.; Bedrosian, T. A.
10.1101/2023.11.29.569243 — neuroscience — Posted on 2023-11-30
105 Multitrait engineering of Hassawi red rice for sustainable cultivation
Sedeek, K.; Mohammed, N.; Zhou, Y.; Zuccolo, A.; Sanikommu, K.; Kantharajappa, S.; Al-Bader, N.; Tashkandi, M.; Wing, R. A.; Mahfouz, M. M.
10.1101/2023.11.28.569140 — bioengineering — Posted on 2023-11-30
106 Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes
Scardigli, M.; Pasek, M.; Santini, L.; Palandri, C.; Conti, E.; Crocini, C.; Campione, M.; Loew, L.; de Vries, A. A. F.; Pijnappels, D.; Pavone, F.; Poggesi, C.; Cerbai, E.; Coppini, R.; Kohl, P.; Ferraninti, C.; Sacconi, L.
10.1101/2023.11.29.569144 — physiology — Posted on 2023-11-30
110 DNA Double-Strand Break Movement in Heterochromatin Depends on the Drosophila Histone Acetyltransferase Gcn5.
Kendek, A.; Sandron, A.; Lambooij, J.-P.; Colmenares, S. U.; Sobrevals Alcaraz, P.; van Es, R.; Pociunaite, S. M.; Gooijers, I.; de Groot, L.; Karpen, G.; Janssen, A.
10.1101/2023.11.30.569406 — cell biology — Posted on 2023-11-30
111 Swi4-dependent SWI4 transcription couples cell size to cell cycle commitment
Goswami, P.; Ghimire, A.; Coffin, C.; Cheng, J.; Coulombe-Huntington, J.; Ghazal, G.; Thattikota, Y.; Tollis, S.; Tyers, M.; Royer, C. A.
10.1101/2023.11.29.569332 — cell biology — Posted on 2023-11-30
113 A synthetic elastic protein as molecular prosthetic candidate to strengthen vascular wall elasticity
Hoareau, M.; Lorion, C.; Lecoq, L.; Berthier, A.; Pierrat, B.; Avril, S.; Pirot, F.; Sommer, P.; Sohier, J.; Lambert, E.; Debret, R.
10.1101/2023.11.30.569188 — cell biology — Posted on 2023-11-30
115 Haems relevance genuine? Re-visiting the roles of TANGO2 homologues including HRG-9 and HRG-10 in C. elegans
Sandkuhler, S. E.; Youngs, K.; Owlett, L.; Bandora, M.; Naaz, A.; Kim, E. S.; Wang, L.; Wojtovich, A. P.; Gupta, V. A.; Sacher, M.; Mackenzie, S. J.
10.1101/2023.11.29.569072 — cell biology — Posted on 2023-11-30
116 PP2A-B55alpha,delta phosphatase counteracts Ki67-dependent chromosome individualization during mitosis
Sanz-Flores, M.; Ruiz-Torres, M.; Aguirre-Portoles, C.; El-Bakkali, A.; Salvador-Barbero, B.; Villarroya-Beltri, C.; Ortega, S.; Megias, D.; Gerlich, D. W.; Alvarez-Fernandez, M.; Malumbres, M.
10.1101/2023.11.30.569375 — cell biology — Posted on 2023-11-30
117 Cohesin chromatin loop formation by an extrinsic motor
Guerin, T. M.; Barrington, C.; Pobegalov, G.; Molodtsov, M. I.; Uhlmann, F.
10.1101/2023.11.30.569410 — molecular biology — Posted on 2023-11-30
121 Altered Metabolism and DAM-signatures in Female Brains and Microglia with Aging
Cleland, N. R.; Potter, G. J.; Buck, C.; Quang, D.; Oldham, D.; Niemeyer, C. S.; Saviola, A.; Neal, M.; Dobrinskikh, E.; Bruce, K. D.
10.1101/2023.11.28.569104 — neuroscience — Posted on 2023-11-30
123 Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity
Lian, C.; Zhang, C.; Tian, P.; Tan, Q.; Wei, Y.; Zhang, Q.; Wang, Z.; Zhang, Q.; Zhong, M.; Zhou, L.-Q.; Ke, X.; Zhang, H.; Zhu, Y.; Li, Z.; Cheng, J.; Wei, G.-H.
10.1101/2023.11.28.569112 — cancer biology — Posted on 2023-11-30
126 Benchmarking AlphaSC: A Leap in Single-Cell Data Processing
Vuong, H.; Luu, T.; Nguyen, N.; Tra, N.; Nguyen, H.; Nguyen, H.; Truong, T.; Pham, S.
10.1101/2023.11.28.569108 — bioinformatics — Posted on 2023-11-30
127 Generalizable features for the diagnosis of infectious disease, autoimmunity and cancer from adaptive immune receptor repertoires
Xu, Z.; Ismanto, H. S.; Saputri, D. S.; Haruna, S.; Wilamowski, J.; Teraguchi, S.; Sengupta, A.; Standley, D. M.
10.1101/2023.11.28.569125 — bioinformatics — Posted on 2023-11-30
128 Streamlining remote nanopore data access with slow5curl
Wong, B.; Ferguson, J. M.; Gamaarachchi, H.; Deveson, I. W.
10.1101/2023.11.28.569128 — bioinformatics — Posted on 2023-11-30
129 Artificial environment impact: O2 concentration changes between IVM and IVF alter embryo production, metabolism, and epigenetic marks
Brunhara Cruz, J.; Miziara Nogueira, C.; Sangalli, J. R.; Perecin Nociti, R.; Ambrizi, D. R.; Bridi, A.; Pinzon, J.; Bianchi Rodrigues Alves, M.; Fernanda Martins Hossepian de Lima, V.; Watanabe, Y.; Fernandes Bressan, F.; Vieira Meirelles, F.; Vilar Sampaio, R.
10.1101/2023.11.28.569089 — developmental biology — Posted on 2023-11-30
133 Circadian regulation of macromolecular complex turnover and proteome renewal
Seinkmane, E.; Edmondson, A. L.; Peak-Chew, S. Y.; Zeng, A.; Rzechorzek, N. M.; James, N. R.; West, J. A.; Munns, J.; Wong, D. C.; Beale, A. D.; O'Neill, J. S.
10.1101/2022.09.30.509905 — cell biology — Posted on 2023-11-30
135 Human Heart Failure Alters Mitochondria and Fiber 3D Structure Triggering Metabolic Shifts
Vue, Z.; Ajayi, P. T.; Neikirk, K.; Murphy, A.; Prasad, P.; Jenkins, B. C.; Vang, L.; Garza-Lopez, E.; Mungai, M.; Marshall, A. G.; Beasley, H. K.; Killion, M.; Parker, R.; Anukodem, J.; Lavine, K.; Ajijola, O.; Mobley, B.; Dai, D.-F.; Exil, V.; Kirabo, A.; Ru Su, Y.; Tomasek, K.; Zhang, X.; Wanjalla, C. N.; Hubert, D. L.; Phillips, M. A.; McReynolds, M.; Glancy, B.; Hinton, A.
10.1101/2023.11.28.569095 — physiology — Posted on 2023-11-30
139 Diagnosis of planktonic trophic network dynamics with sharp qualitative changes
Gaucherel, C.; Fayolle, S.; Savelli, R.; Philippine, O.; Pommereau, F.; Dupuy, C.
10.1101/2023.06.29.547055 — ecology — Posted on 2023-11-30
141 Structure and dynamics of human cardiac fibroblast nanotubes
Schmid-Herbstritt, S. C.; Stief, G.; Greiner, J.; Felekary, A.; Madl, J.; Zeidler, V.; Heer, J.; Iaconianni, P.; Koch, M.; Kollmar, K.; Walz, C.; Nubling, S.; Kok, T.; Pronto, J. R.; Kutschka, I.; Voigt, N.; Morgan, G.; Dienert, J.; Brox, T.; Briquez, P.; Peyronnet, R.; Rohrbach, A.; Kohl, P.; Rog-Zielinska, E. A.
10.1101/2023.11.28.568871 — cell biology — Posted on 2023-11-30
143 Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers
Krasik, S. V.; Bryushkova, E. A.; Sharonov, G. V.; Myalik, D. S.; Shurganova, E. V.; Komarov, D. V.; Shagina, I. A.; Shpudeiko, P. S.; Turchaninova, M. A.; Vakhitova, M. T.; Samoylenko, I. V.; Marinov, D. T.; Demidov, L. V.; Zagainov, V. E.; Chudakov, D. M.; Serebrovskaya, E. O.
10.1101/2023.04.16.537028 — immunology — Posted on 2023-11-30
144 Abstract representations emerge in human hippocampal neurons during inference behavior
Courellis, H. S.; Minxha, J.; Ramirez Cardenas, A.; Kimmel, D. L.; Reed, C. M.; Valiante, T. A.; Salzman, C. D.; Mamelak, A. N.; Fusi, S.; Rutishauser, U.
10.1101/2023.11.10.566490 — neuroscience — Posted on 2023-11-30
146 Improving the reliability of fMRI-based predictions of intelligence via semi-blind machine learning
Lohmann, G.; Heczko, S.; Mahler, L.; Wang, Q.; Steiglechner, J.; Kumar, V. J.; Roost, M.; Jost, J.; Scheffler, K.
10.1101/2023.11.03.565485 — neuroscience — Posted on 2023-11-30
148 A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction
Li, X.; Gamuyao, R.; Wu, M.-L.; Cho, W. J.; Kurtz, N. B.; King, S. V.; Petersen, R. A.; Stabley, D. R.; Lindow, C.; Climer, L.; Shirinifard, A.; Ferrara, F.; Throm, R. E.; Robinson, C. G.; Carisey, A.; Tebo, A. G.; Chang, C.-L.
10.1101/2023.11.29.569289 — cell biology — Posted on 2023-11-29
150 HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
Rouse, J. R.; Danner, R.; Wahhab, A.; Pereckas, M.; McClune, M.; Steere, A. C.; Strle, K.; Jutras, B. L.; Lochhead, R. B.
10.1101/2023.11.21.568066 — immunology — Posted on 2023-11-29
153 Hierarchical Modelling of Crossing Fibres in the White Matter
Rafipoor, H.; Lange, F. J.; Arthofer, C.; Cottaar, M.; Jbabdi, S.
10.1101/2023.05.24.542138 — neuroscience — Posted on 2023-11-29
154 Converging Topographic Axes of Connectivity and Genetic Architectures Scaffold Cortical Patterning
Li, D.; Wang, Y.; Ma, L.; Shi, W.; Lu, Y.; Wang, H.; Cheng, X.; Wang, Y.; Gao, C.; Cheng, L.; Erichsen, C.; Zhang, Y.; Yang, Z.; Eickhoff, S.; Chen, C.-h.; Chu, C.; Fan, L.
10.1101/2023.09.06.556618 — neuroscience — Posted on 2023-11-29
158 Y and Mitochondrial Chromosomes in the Heterogeneous Stock Rat Population
Okamoto, F.; Chitre, A. S.; Sanches, T. M.; Chen, D.; Munro, D.; NIDA Center for GWAS in Outbred Rats, ; Polesskaya, O.; Palmer, A. A.
10.1101/2023.11.29.566473 — bioinformatics — Posted on 2023-11-29
160 Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors
Berrios, K. N.; Barka, A.; Gill, J.; Serrano, J. C.; Bailer, P. F.; Parker, J. B.; Evitt, N. H.; Gajula, K. S.; Shi, J.; Kohli, R. M.
10.1101/2022.12.03.518995 — biochemistry — Posted on 2023-11-29
161 Interactive visualization of whole eukaryote genome alignments using NCBI's Comparative Genome Viewer (CGV)
Rangwala, S. H.; Rudnev, D. V.; Ananiev, V. V.; Asztalos, A.; Benica, B.; Borodin, E. A.; Bouk, N.; Evgeniev, V. I.; Kodali, V. K.; Lotov, V.; Mozes, E.; Oh, D.-H.; Omelchenko, M. V.; Savkina, S.; Sukharnikov, E.; Virothaisakun, J.; Murphy, T. D.; Pruitt, K. D.; Schneider, V. A.
10.1101/2023.10.30.564672 — genomics — Posted on 2023-11-29
162 pH selects for distinct N2O-reducing microbiomes in tropical soil microcosms
Sun, Y.; Yin, Y.; He, G.; Cha, G.; Ayala-del-Rio, H.; Gonzalez, G.; Konstantinidis, K. T.; Loeffler, F. E.
10.1101/2023.11.29.569236 — microbiology — Posted on 2023-11-29
167 Metabolism-focused CRISPR screen unveils Mitochondrial Pyruvate Carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
Furusawa, T.; Cavero, R.; Liu, Y.; Li, H.; Xu, X.; Andresson, T.; Reinhold, W.; White, O.; Boufraqech, M.; Meyer, T. J.; Hartmann, O.; Diefenbacher, M. E.; Pommier, Y.; Weyemi, U.
10.1101/2023.11.29.569226 — cancer biology — Posted on 2023-11-29
170 CRISPR-Cas12a exhibits metal-dependent specificity switching
Nguyen, G. T.; Schelling, M. A.; Buscher, K. A.; Sritharan, A.; Sashital, D. G.
10.1101/2023.11.29.569287 — biochemistry — Posted on 2023-11-29
171 PrimPol variant V102A with altered primase and polymerase activities
Boldinova, E. O.; Filina, Y. V.; Miftakhova, R. R.; Shamsutdinova, Y. F.; Makarova, A. V.
10.1101/2023.11.29.569302 — biochemistry — Posted on 2023-11-29
172 Oligomerisation mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptor
Vela-Rodriguez, C.; Yang, C.; Alanen, H. I.; Eki, R.; Abbas, T. A.; Maksimainen, M. M.; Glumoff, T.; Duman, R.; Wagner, A.; Paschal, B. M.; Lehtiö, L.
10.1101/2023.11.29.569193 — biochemistry — Posted on 2023-11-29
173 Phosphogluconolactonase as the linchpin of an efficient pentose phosphate pathway
Phegnon, L.; Perochon, J.; Uttenweiler, S.; Cahoreau, E.; Millard, P.; Letisse, F.
10.1101/2023.11.29.569206 — biochemistry — Posted on 2023-11-29
174 Use of TSAR, Thermal Shift Analysis in R, to identify Folic Acid as a Molecule that Interacts with HIV-1 Capsid
Gao, X. M.; McFadden, W. M.; Wen, X.; Emanuelli, A.; Lorson, Z. C.; Zhang, H.; Kirby, K. A.; Sarafianos, S. G.
10.1101/2023.11.29.569293 — biochemistry — Posted on 2023-11-29
175 Upper bound on the mutational burden imposed by a CRISPR-Cas9 gene-drive element
Overton, M. S.; Guy, S. E.; Chen, X.; Martsul, A.; Carolino, K.; Akbari, O.; Meyer, J. R.; Kryazhimskiy, S.
10.1101/2023.11.28.569142 — evolutionary biology — Posted on 2023-11-29
178 Single nucleus transcriptome of a "Super RV" shows increased insulin and angiogenesis signaling
Turaga, D.; Li, X.; Zhao, Y.; Tsai, C.-R.; Moreira, A.; Hickey, E.; Adachi, I.; Martin, J. F.
10.1101/2023.11.28.569092 — developmental biology — Posted on 2023-11-29
179 NUDC is critical for rod photoreceptor function, maintenance, and survival
Garner, M. A.; Hubbard, M. G.; Boitet, E. R.; Hubbard, S. T.; Gade, A.; Ying, G.; Jones, B. W.; Baehr, W.; Gross, A. K.
10.1101/2023.11.28.568878 — cell biology — Posted on 2023-11-29
180 Targeting PKC alleviates iron overload in diabetes and hemochromatosis
Banerjee, S.; Lu, S.; Jain, A.; Wang, I.; Tao, H.; Srinivasan, S.; Nemeth, E.; He, P.
10.1101/2023.11.28.569107 — cell biology — Posted on 2023-11-29
184 Role of Tyrosine Phosphorylation in PTP-PEST
T S, S.; Manikandan, A.; Manoj, N.; Dixit, M.; Vemparala, S.
10.1101/2023.11.28.569137 — biophysics — Posted on 2023-11-29
188 Framewise multi-echo distortion correction for superior functional MRI
Van, A. N.; Montez, D. F.; Laumann, T. O.; Suljic, V.; Madison, T.; Baden, N. J.; Ramirez-Perez, N.; Scheidter, K. M.; Monk, J. S.; Whiting, F. I.; Adeyemo, B.; Chauvin, R. J.; Krimmel, S. R.; Metoki, A.; Rajesh, A.; Roland, J. L.; Salo, T.; Wang, A.; Weldon, K. B.; Sotiras, A.; Shimony, J. S.; Kay, B. P.; Nelson, S. M.; Tervo-Clemmens, B.; Marek, S. A.; Vizioli, L.; Yacoub, E.; Satterthwaite, T. D.; Gordon, E. M.; Fair, D. A.; Tisdall, D.; Dosenbach, N. U. F.
10.1101/2023.11.28.568744 — bioengineering — Posted on 2023-11-29
189 Encapsulation of AAV into protein vault nanoparticles as a novel solution to gene therapy's neutralizing antibody problem
Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lagor, W.; Bao, G.; Ponnazhagan, S.; McNally, R.; Rome, L.; Curiel, D.
10.1101/2023.11.29.569229 — bioengineering — Posted on 2023-11-29
190 Tyrosine transfer RNA levels and modifications during blood-feeding and vitellogenesis in the mosquito, Aedes aegypti
Kelley, M.; Holmes, C. J.; Herbert, C.; Rayhan, A.; Joves, J.; Frigard, R.; Singh, K.; Limbach, P. A.; Addepalli, B.; Benoit, J. B.
10.1101/2023.11.29.569187 — biochemistry — Posted on 2023-11-29
191 Filter-aided expansion proteomics
Dong, Z.; Zhu, Y.; Zhang, F.; Wu, C.; Chen, T.; Jiang, W.; Xiao, Q.; Zheng, S.; Piatkevich, K. D.; Guo, T.
10.1101/2023.11.29.569242 — biochemistry — Posted on 2023-11-29
193 Kinetic and structural characterization of human NUDIX hydrolase NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis
Scaletti, E. R.; Unterlass, J. E.; Almlof, I.; Koolmeister, T.; Vallin, K. S.; Kapsitidou, D.; Helleday, T.; Stenmark, P.; Jemth, A.-S.
10.1101/2023.11.29.569174 — biochemistry — Posted on 2023-11-29
194 Probabilistic ecological risk assessment for deep-sea mining: a Bayesian Network for Chatham Rise, SW Pacific Ocean
Kaikkonen, L.; Clark, M. R.; Leduc, D.; Nodder, S. D.; Rowden, A. A.; Bowden, D. A.; Beaumont, J.; Cummings, V.
10.1101/2023.11.28.569078 — ecology — Posted on 2023-11-29
195 High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer
Schmidt, T. T.; Tyer, C.; Rughani, P.; Haggblom, C.; Jones, J. R.; Dai, X.; Frazer, K. A.; Gage, F. H.; Juul, S.; Hickey, S.; Karlseder, J.
10.1101/2023.11.28.569082 — cell biology — Posted on 2023-11-29
196 Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice
Rinne, V.; Grondahl-Yli-Hannuksela, K.; Fair-Makela, R.; Salmi, M.; Rantakari, P.; Lonnberg, T.; Alinikula, J.; Pietikainen, A.; Hytonen, J.
10.1101/2023.11.29.569164 — molecular biology — Posted on 2023-11-29
207 Targeting with structural analogs of natural products the purine salvage pathway in Leishmania (Leishmania) infantum by computer-aided drug design approaches
Ccahuana, H. L. B.; Rodriguez, E. G. C.; Lopez, A. E. C.; Galdino, A. S.; Machado de Avila, R. A.; Giunchetti, R. C.; Coelho, E. A. F.; Fumagalli, M. A. C.
10.1101/2023.11.28.569055 — bioinformatics — Posted on 2023-11-29
208 Measuring technical variability in Illumina DNA methylation microarrays
Butler, A.; Kras, J.; Chwalek, K.; Ramos, E. I.; Bishof, I.; Vogel, D.; Vera, D. L.
10.1101/2023.11.28.569087 — bioinformatics — Posted on 2023-11-29
209 Multi-ContrastiveVAE disentangles perturbation effects in single cell images from optical pooled screens
Wang, Z. J.; Lopez, R.; Huetter, J.-C.; Kudo, T.; Yao, H.; Hanslovsky, P.; Hoeckendorf, B.; Regev, A.
10.1101/2023.11.28.569094 — bioinformatics — Posted on 2023-11-29
210 Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R
Nguyen, H. T.; Gurvich, N.; Gillrie, M. R.; Offeddu, G.; Humayun, M.; Kan, E. L.; Wan, Z.; Coughlin, M. F.; Zhang, C.; Vu, V.; Lee, S. W. L.; Tan, S.-L.; Barbie, D.; Hsu, J.; Kamm, R. D.
10.1101/2023.11.28.568627 — bioengineering — Posted on 2023-11-29
211 Wearable Disposable Electrotherapy
FallahRad, M.; Chaudhry, Z.; Belali Koochesfahani, M.; Bhuiyan, R.; Zaman, M.; Liu, T.; Saha, K.; Diaz Uraga, M. R.; Thahsin, M.; Couzis, A.; Bikson, M.
10.1101/2023.11.28.569062 — bioengineering — Posted on 2023-11-29
215 Expansion of human hematopoietic stem cells by inhibiting translation
Li, C.; Shin, H.; Bhavanasi, D.; Liu, M.; Yu, X.; Peslak, S. A.; Liu, X.; Alvarez--Dominguez, J. R.; Blobel, G. A.; Gregory, B. D.; Huang, J.; Klein, P. S.
10.1101/2023.11.28.568925 — cell biology — Posted on 2023-11-29
216 Engraftment and injury repair in regionally conditioned rat lung in vivo by lung progenitors derived from human pluripotent stem cells.
Liu, H.-Y.; Predella, C.; Chen, Y.-W.; Wang, J.; Fare, S.; Pezet, M. G.; Liang, S.; Saqi, A.; Murray, J. W.; Vunjak-Novakovic, G.; Snoeck, H.-W.; Dorrello, N. V.
10.1101/2023.11.28.569060 — cell biology — Posted on 2023-11-29
217 Length control emerges from cytoskeletal network geometry
McInally, S. G.; Reading, A. J. B.; Rosario, A.; Jelenkovic, P. R.; Goode, B.; Kondev, J.
10.1101/2023.11.28.569063 — cell biology — Posted on 2023-11-29
218 Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins
Page, K. R.; Nguyen, V. N.; Pleiner, T.; Tomaleri, G. P.; Wang, M. L.; Guna, A.; Wang, T.-Y.; Chou, T.-F.; Voorhees, R. M.
10.1101/2023.11.28.569054 — cell biology — Posted on 2023-11-29
219 Pathogenic IgE-fated B cell memory retains functional plasticity
Bruton, K.; Phelps, A.; Ariaz, A.; Walker, T.; Wen, J.; Khavkine-Binstock, S. S.; Fang, A.; Mann-Delany, O.; Knudsen, N. P. H.; Gadkar, S.; Grydziuszko, E.; Koenig, J. F.; Gagnon, A.; Waserman, S.; Andersen, P. S.; Jordana, M.
10.1101/2023.11.28.567094 — immunology — Posted on 2023-11-29
221 Mitochondrial complex I deficiency stratifies idiopathic Parkinson's disease
Flones, I.; Toker, L.; Sandnes, D. A.; Castelli, M.; Mostafavi, S.; Lura, N.; Shadad, O.; Fernandez-Vizarra, E.; Painous, C.; Perez-Soriano, A.; Compta, Y.; Molina-Porcel, L.; Alves, G.; Tysnes, O.-B.; Dolle, C.; Nido, G. S.; Tzoulis, C.
10.1101/2023.09.22.558615 — neuroscience — Posted on 2023-11-29
224 (R,S)-ketamine's rapid-acting antidepressant effects are modulated by NR2B- containing NMDA receptors on adult-born hippocampal neurons
Bulthuis, N. E.; McGowan, J. C.; Ladner, L. R.; LaGamma, C. T.; Lim, S. C.; Shubeck, C. X.; Brachman, R. A.; Sydnor, E.; Pavlova, I. P.; Seo, D.-o.; Drew, M. R.; Denny, C. A.
10.1101/2023.11.28.569043 — neuroscience — Posted on 2023-11-29
225 Cell-mediated cholesterol crystal processing and clearance observed by 3D cryo-imaging in human atherosclerotic plaques
Shenkar, J. C.; Kaestner, A.; Rechav, K.; Brumfeld, V.; Kaplan-Ashiri, I.; Avinoam, O.; Speter, C.; Halak, M.; Kruth, H.; Addadi, L.
10.1101/2023.11.28.568890 — pathology — Posted on 2023-11-29
226 Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion
Shvefel, S. C.; Pai, J.; Cao, Y.; Pal, L.; Levy, R.; Yao, W.; Cheng, K.; Zemanek, M.; Bartok, O.; Weller, C.; Yin, Y.; Du, P.; Yakubovich, E.; Orr, I.; Ben-Dor, S.; Oren, R.; Fellus-Alyagor, L.; Golani, O.; Goliand, I.; Ranmar, D.; Savchenko, I.; Ketrarou, N.; Schaffer, A. A.; Ruppin, E.; Satpathy, A.; Samuels, Y.
10.1101/2023.11.29.569032 — cancer biology — Posted on 2023-11-29
229 OmicVerse: A single pipeline for exploring the entire transcriptome universe
Zeng, Z.; Ma, Y.; Hu, L.; Liu, P.; Tan, B.; Wang, Y.; Xing, C.; Xiong, Y.; Du, H.
10.1101/2023.06.06.543913 — bioinformatics — Posted on 2023-11-29
230 Origin and evolution of the bread wheat D genome
Cavalet-Giorsa, E.; Gonzalez-Munoz, A.; Athiyannan, N.; Holden, S.; Salhi, A.; Gardener, C.; Quiroz-Chavez, J.; Rustamova, S. M.; Elkot, A. F.; Patpour, M.; Rasheed, A.; Mao, L.; Lagudah, E. S.; Periyannan, S. K.; Sharon, A.; Himmelbach, A.; Reif, J. C.; Knauft, M.; Mascher, M.; Stein, N.; Chayut, N.; Ghosh, S.; Perovic, D.; Putra, A.; Perera, A. B.; Hu, C.-Y.; Yu, G.; Ahmed, H. I.; Laquai, K. D.; Rivera, L. F.; Chen, R.; Wang, Y.; Gao, X.; Liu, S.; Raupp, W. J.; Olson, E. L.; Lee, J.-Y.; Chhuneja, P.; Kaur, S.; Zhang, P.; Park, R. F.; Ding, Y.; Liu, D.-C.; Li, W.; Nasyrova, F. Y.; Dvorak, J.;
10.1101/2023.11.29.568958 — genomics — Posted on 2023-11-29
232 Regulators of health and lifespan extension in genetically diverse mice on dietary restriction
Di Francesco, A.; Deighan, A. G.; Litichevskiy, L.; Chen, Z.; Luciano, A.; Robinson, L.; Garland, G.; Donato, H.; Schott, W.; Wright, K. M.; Raj, A.; Prateek, G. V.; Mullis, M.; Hill, W.; Zediel, M.; Peters, L.; Harding, F.; Botstein, D.; Korstanje, R.; Thaiss, C.; Freund, A.; Churchill, G. A.
10.1101/2023.11.28.568901 — genetics — Posted on 2023-11-29
239 The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy
Broadbent, D. G.; McEwan, C. M.; Tsang, T.-M.; Poole, D. M.; Naylor, B. C.; Price, J. C.; Schmidt, J. C.; Andersen, J. L.
10.1101/2023.11.28.569058 — cell biology — Posted on 2023-11-29
241 The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-Lck interactions
Lee, M. S.; Tuohy, P. J.; Kim, C. Y.; Yost, P. P.; Lichauco, K.; Parrish, H. L.; Van Doorslaer, K.; Kuhns, M. S.
10.1101/2023.05.05.539613 — immunology — Posted on 2023-11-29
243 Conduction Velocity, G-ratio, and Extracellular Water as Microstructural Characteristics of Autism Spectrum Disorder
Newman, B. T.; Jacokes, Z.; Venkadesh, S. T.; Webb, S. J.; Kleinhans, N. M.; McPartland, J. C.; Druzgal, T. J.; Pelphrey, K. A.; Van Horn, J. D.; For the GENDAAR Research Consortium,
10.1101/2023.07.23.550166 — neuroscience — Posted on 2023-11-29
244 Short tandem repeat mutations regulate gene expression in colorectal cancer
Verbiest, M. A.; Lundström, O.; Xia, F.; Baudis, M.; Bilgin Sonay, T.; Anisimova, M.
10.1101/2023.11.29.569189 — cancer biology — Posted on 2023-11-29
245 CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism
Xu, M.; Neelands, T.; Powers, A. S.; Liu, Y.; Miller, S. D.; Pintilie, G.; Du Bois, J.; Dror, R. O.; Chiu, W.; Maduke, M.
10.1101/2023.08.13.553136 — biophysics — Posted on 2023-11-29
250 The structural landscape and diversity of Pyricularia oryzae MAX effectors revisited
Lahfa, M.; BARTHE, P.; DEGUILLEN, K.; Cesari, S.; RAJI, M.; Kroj, T.; Le Naour--Vernet, M.; Hoh, F.; Gladieux, P.; ROUMESTAND, C.; Gracy, J.; Declerck, N.; Padilla, A.
10.1101/2023.09.26.559520 — bioinformatics — Posted on 2023-11-29
251 Competition for shared resources increases the impact of propagule size during coalescence of gut microbial communities
Goldman, D. A.; Xue, K. S.; Parrott, A. B.; Lopez, J. G.; Vila, J. C.; Petrov, D. A.; Good, B. H.; Relman, D. A.; Huang, K. C.
10.1101/2023.11.29.569120 — ecology — Posted on 2023-11-29
252 Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning
Lei, R.; Qing, E.; Odle, A.; Yuan, M.; Tan, T. J. C.; So, N.; Ouyang, W. O.; Wilson, I. A.; Gallagher, T.; Perlman, S.; Wu, N. C.; Wong, L. Y. R.
10.1101/2023.11.28.569051 — microbiology — Posted on 2023-11-29
253 Stability of Oral and Fecal Microbiome at Room Temperature: Impact on Diversity
Rius-Sansalvador, B.; Bars-Cortina, D.; Khannous-Lleiffe, O.; Garcia-Serrano, A.; Guino, E.; Saus, E.; Gabaldon, T.; Moreno, V.; Obon-Santacana, M.
10.1101/2023.11.28.568988 — microbiology — Posted on 2023-11-29
254 copepodTCR: Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling
Kovaleva, V. A.; Pattinson, D. J.; Barton, C.; Chapin, S. R.; Minerva, A. A.; Richards, K. A.; Sant, A. J.; Thomas, P. G.; Pogorelyy, M. V.; Meyer, H. V.
10.1101/2023.11.28.569052 — immunology — Posted on 2023-11-29
256 Structural snapshots of phenuivirus cap-snatching and transcription
Williams, H. M.; Thorkelsson, S. R.; Vogel, D.; Busch, C.; Milewski, M.; Cusack, S.; Grunewald, K.; Quemin, E. R. J.; Rosenthal, M.
10.1101/2023.11.29.569195 — biochemistry — Posted on 2023-11-29
258 A deep lung cell atlas reveals cytokine-mediated lineage switching of a rare cell progenitor of the human airway epithelium
Waghray, A.; Monga, I.; Lin, B.; Shah, V.; Slyper, M.; Giotti, B.; Xu, J.; Waldman, J.; Dionne, D.; Nguyen, L. T.; Lou, W.; Cai, P.; Park, E.; Muus, C.; Sun, J.; Surve, M. V.; Yang, L. C. C.; Rozenblatt-Rosen, O.; Dolerey, T. M.; Saladi, S. V.; Tsankov, A. M.; Regev, A.; Rajagopal, J.
10.1101/2023.11.28.569028 — cell biology — Posted on 2023-11-29
259 Structure and dynamics of human cardiac fibroblast nanotubes
Schmid-Herbstritt, S. C.; Stief, G.; Greiner, J.; Felekary, A.; Madl, J.; Zeidler, V.; Heer, J.; Iaconianni, P.; Koch, M.; Kollmar, K.; Walz, C.; Nubling, S.; Kok, T.; Pronto, J. R.; Kutschka, I.; Voigt, N.; Morgan, G.; Dienert, J.; Brox, T.; Briquez, P.; Peyronnet, R.; Rohrbach, A.; Kohl, P.; Rog-Zielinska, E. A.
10.1101/2023.11.28.568871 — cell biology — Posted on 2023-11-29
260 Spartin-mediated lipid transfer facilitates lipid droplet turnover
Wan, N.; Hong, Z.; Parson, M. A.; Korfhage, J. L.; Burke, J. E.; Melia, T.; Reinisch, K.
10.1101/2023.11.29.569220 — cell biology — Posted on 2023-11-29
262 Live Malassezia strains isolated from the mucosa of patients with ulcerative colitis
Cho, Y.-J.; Yang, J.; Shin, S. Y.; Kim, H. K.; Rintarhat, P.; Park, M.; Sung, M.; Lagree, K.; Underhill, D.; Lee, D.-W.; Choi, C. H.; Yang, C.-S.; Jung, W. H.
10.1101/2023.11.28.569113 — microbiology — Posted on 2023-11-29
263 Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice
Litichevskiy, L.; Considine, M.; Gill, J.; Shandar, V.; Cox, T. O.; Descamps, H. C.; Wright, K. M.; Amses, K. R.; Dohnalova, L.; Liou, M. J.; Tetlak, M.; Galindo-Fiallos, M. R.; Wong, A. C.; Lundgren, P.; Kim, J.; Uhr, G. T.; Rahman, R. J.; Mason, S.; Merenstein, C.; Bushman, F. D.; Raj, A.; Harding, F.; Chen, Z.; Prateek, G. V.; Mullis, M.; Deighan, A. G.; Robinson, L.; Tanes, C.; Bittinger, K.; Chakraborty, M.; Bhatt, A. S.; Li, H.; Barnett, I.; Davenport, E. R.; Broman, K. W.; Cohen, R. L.; Botstein, D.; Freund, A.; Di Francesco, A.; Churchill, G. A.; Li, M.; Thaiss, C. A.
10.1101/2023.11.28.568137 — microbiology — Posted on 2023-11-29
264 Fecal transplant allows transmission of the gut microbiota in honey bees
Cabirol, A.; Chhun, A.; Liberti, J.; Kesnerova, L.; Neuschwander, N.; Schaerli, Y.; Engel, P.
10.1101/2023.11.29.569223 — microbiology — Posted on 2023-11-29
267 Morphometrics and phylogenomics of coca (Erythroxylum spp.) illuminate its reticulate evolution, with implications for taxonomy
Przelomska, N.; Diaz, R.; Avila, F. A.; Ballen, G. A.; Cortes-B, R.; Kistler, L.; Chitwood, D. H.; Charitonidou, M.; Renner, S. S.; Perez-Escobar, O. A.; Antonelli, A.
10.1101/2023.11.28.569066 — plant biology — Posted on 2023-11-29
275 Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor
Blum, S. M.; Zlotoff, D. A.; Smith, N. P.; Kernin, I. J.; Ramesh, S.; Zubiri, L.; Caplin, J.; Samanta, N.; Martin, S. C.; Tirard, A.; Sen, P.; Song, Y.; Barth, J. L.; Slowikowski, K.; Nasrallah, M.; Tantivit, J.; Manakongtreecheep, K.; Arnold, B. Y.; McGuire, J.; Pinto, C. J.; McLoughlin, D.; Jackson, M.; Chan, P.; Lawless, A.; Sharova, T.; Nieman, L. T.; Gainor, J. F.; Juric, D.; Mino-Kenudsen, M.; Sullivan, R. J.; Boland, G. M.; Stone, J. R.; Thomas, M. F.; Neilan, T. G.; Reynolds, K. L.; Villani, A.-C.
10.1101/2023.09.15.557794 — immunology — Posted on 2023-11-29
276 Altered structural connectivity and functional brain dynamics in individuals with heavy alcohol use
Singleton, S. P.; Velidi, P.; Schilling, L.; Luppi, A. I.; Jamison, K.; Parkes, L.; Kuceyeski, A.
10.1101/2023.11.27.568762 — neuroscience — Posted on 2023-11-29
277 Removal of pomt1 in zebrafish leads to loss of α-dystroglycan glycosylation and dystroglycanopathy phenotypes
Karas, B. F.; Terez, K. R.; Mowla, S.; Battula, N.; Flannery, K. P.; Gural, B. M.; Aboussleman, G.; Mubin, N.; Manzini, C.
10.1101/2022.10.15.512359 — neuroscience — Posted on 2023-11-29
282 Decoding Heterogenous Single-cell Perturbation Responses
Song, B.; Liu, D.; Dai, W.; McMyn, N.; Wang, Q.; Yang, D.; Krejci, A.; Vasilyev, A.; Untermoser, N.; Loregger, A.; Song, D.; Williams, B.; Rosen, B.; Cheng, X.; Chao, L.; Kale, H. T.; Zhang, H.; Diao, Y.; Bürckstümmer, T.; Siliciano, J. M.; Li, J. J.; Siliciano, R.; Huangfu, D.; Li, W.
10.1101/2023.10.30.564796 — bioinformatics — Posted on 2023-11-29
283 Hunger drives switching and searching response in a social predator
Prokopenko, C.; Zabihi-Seissan, S.; Dupont, D.; Kingdon, K.; Turner, J. W.; Vander Wal, E.
10.1101/2023.11.27.568908 — ecology — Posted on 2023-11-29
284 GPRC5A regulates keratinocyte adhesion and migration through nuclear translocation of its C-terminus region
Chanteloube, S.; Ya, C.; Le Provost, G.; Berthier, A.; Dieryckx, C.; Vadon-Le Goff, S.; Nadal, F.; Fromy, B.; Debret, R.
10.1101/2023.11.28.569012 — cell biology — Posted on 2023-11-29
285 Control limitations in the null-space of the wrist muscle system
Lee, M.-J.; Eden, J.; Gurgone, S.; Berger, D. J.; Borzelli, D.; d'Avella, A.; Mehring, C.; Burdet, E.
10.1101/2023.11.28.568721 — neuroscience — Posted on 2023-11-29
290 Mime: A flexible machine-learning framework to construct and visualize models for clinical characteristics prediction and feature selection
Liu, H.; Zhang, W.; Zhang, Y.; Adegboro, A. A.; Dai, L.; Pan, Z.; Li, W.; Peng, K.; Fasoranti, D. O.; Wanggou, S.; Li, X.
10.1101/2023.11.28.569007 — bioinformatics — Posted on 2023-11-29
292 Interactome mapping reveals a role for LRP10 in autophagy and NDFIP1-mediated alpha-synuclein secretion
Carreras Mascaro, A.; Ferraro, F.; Boumeester, V.; Breedveld, G.; Dekkers, D. H. W.; Vergouw, L.; de Jong, F. J.; Demmers, J. A.; Bonifati, V.; Mandemakers, W.
10.1101/2023.11.28.569009 — neuroscience — Posted on 2023-11-29
299 Mycelium-bound lipases of psychrophilic and mesophilic fungi as biocatalysts for biodiesel synthesis
Kutyła, M.; Jaszek, N.; Jedrys, W.; Graba, S.; Pluta, E.; Gdula, K.; Batyra, A.; Szczepanska, A.; Sliwa, A.; Cieslak, L.; Marzec-Grzadziel, A.; Trytek, M.
10.1101/2023.11.28.568820 — bioengineering — Posted on 2023-11-29
301 Eco-evolutionary dynamics of partially migratory metapopulations in spatially and seasonally varying environments
Haaland, T. R.; Payo-Payo, A.; Acker, P.; Fortuna, R. R.; Burthe, S.; Ratikainen, I. I.; Daunt, F.; Reid, J. M.
10.1101/2023.11.28.568986 — evolutionary biology — Posted on 2023-11-29
304 Universal Cell Embeddings: A Foundation Model for Cell Biology
Rosen, Y.; Roohani, Y.; Agrawal, A.; Samotorcan, L.; Consortium, T. S.; Quake, S. R.; Leskovec, J.
10.1101/2023.11.28.568918 — cell biology — Posted on 2023-11-29
305 Nanoscale cellular organization of viral RNA and proteins in SARS-CoV-2 replication organelles
Andronov, L.; Han, M.; Zhu, Y.; Roy, A. R.; Barentine, A. E. S.; Garhyan, J.; Qi, L. S.; Moerner, W. E.
10.1101/2023.11.07.566110 — microbiology — Posted on 2023-11-29
306 Cell2Sentence: Teaching Large Language Models the Language of Biology
Levine, D.; Rizvi, S. A.; Levy, S.; Pallikkavaliyaveetil MohammedSheriff, N.; Wu, R.; Han, I.; Zhang, Z.; Fonseca, A.; Chen, X.; Ghadermarzi, S.; Karbasi, A.; Dhodapkar, R. M.; van Dijk, D.
10.1101/2023.09.11.557287 — bioinformatics — Posted on 2023-11-29
307 Bi-parental graph strategy to represent and analyze hybrid plant genomes
Kong, Q.; Jiang, Y.; Wang, Z.; Wang, Z.; Liu, Y.; Gan, Y.; Liu, H.; Gao, X.; Yang, X.; Song, X.; Liu, H.; Shi, J.
10.1101/2023.11.28.568999 — bioinformatics — Posted on 2023-11-29
308 An mRNA-encoded, long-lasting Interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
Beck, J. D.; Diken, M.; Suchan, M.; Streuber, M.; Diken, E.; Kolb, L.; Allnoch, L.; Vascotto, F.; Peters, D.; Beissert, T.; Tuereci, O.; Kreiter, S.; Vormehr, M.; Sahin, U.
10.1101/2023.07.18.549445 — immunology — Posted on 2023-11-29
309 PAH DEFICIENT PATHOLOGY IN HUMANIZED c.1066-11G>A PHENYLKETONURIA MICE
Martinez-Pizarro, A.; Pico, S.; Lopez-Marquez, A.; Rodriguez-Lopez, C.; Montalvo, E.; Alvarez, M.; Castro, M.; Ramon-Maiques, S.; Perez, B.; Lucas, J. J.; Richard, E. M.; Desviat, L. R.
10.1101/2023.11.03.565447 — pathology — Posted on 2023-11-29
310 A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity
Fitzgerald, D.; Roider, T.; Baertsch, M. A.; Kibler, A.; Horlova, A.; Chung, E. K.; Voehringer, H.; Mathioudaki, A.; Budeus, B.; Passerini, V.; Knoll, M.; Mammen, J.; Li, L.; Caille, L.; Czernilofsky, F.; Bruch, P. M.; Liebers, N.; Meyer-Bender, M.; Weigert, O.; Zaugg, J. B.; Nolan, G. P.; Seifert, M.; Dietrich, S.; Huber, W.
10.1101/2023.11.06.565756 — cancer biology — Posted on 2023-11-28
311 HYENA detects non-coding genes activated by distal enhancers in cancer
Yu, A.; Yesilkanal, A. E.; Thakur, A.; Wang, F.; Yang, Y.; Phillips, W.; Wu, X.; Muir, A.; He, X.; Spitz, F.; Yang, L.
10.1101/2023.01.09.523321 — cancer biology — Posted on 2023-11-28
312 Multiplexed 3D Analysis of Cell Plasticity and Immune Niches in Melanoma
Yapp, C.; Nirmal, A. J.; Zhou, F. Y.; Maliga, Z.; Montero Llopis, P.; Murphy, G. F.; Lian, C.; Danuser, G.; Santagata, S.; Sorger, P. K.
10.1101/2023.11.10.566670 — cancer biology — Posted on 2023-11-28
313 Label-free 3-D molecular imaging of living tissues using Raman Spectral Projection Tomography
Stepula, E.; Walther, A. R.; Mehrotra, D.; Jensen, M.; Yuan, M. H.; Pedersen, S. V.; Gentleman, E.; Albro, M. B.; Hedegaard, M. A. B.; Bergholt, M. S.
10.1101/2023.09.23.559025 — bioengineering — Posted on 2023-11-29
315 Genome wide assessment of genetic diversity and transcript variations in 17 accessions of the model diatom Phaeodactylum tricornutum
CHAUMIER, T.; YANG, F.; MANIRAKIZA, E.; AIT MOHAMED, O.; WU, Y.; CHANDOLA, U.; JESUS, B.; Piganeau, G.; Groisillier, A.; Tirichine, L.
10.1101/2023.05.31.543125 — genomics — Posted on 2023-11-29
316 Development of genetically-encoded fluorescent KSR1-based probes to track ceramides during phagocytosis
Girik, V.; Van Ek, L.; Dentand Quadri, I.; Azam, M.; Cruz Cobo, M.; Mandavit, M.; Riezman, I.; Riezman, H.; Gavin, A.-C.; Nunes-Hasler, P.
10.1101/2023.09.27.559623 — cell biology — Posted on 2023-11-29
318 Mitosis sets nuclear homeostasis of cancer cells under confinement
Mouelhi, M.; Saffon, A.; Roinard, M.; Delanoe-Ayari, H.; Monnier, S.; Riviere, C.
10.1101/2023.05.11.540326 — biophysics — Posted on 2023-11-29
319 Bioorthogonal metabolic labeling of the virulence factor phenolic glycolipid in mycobacteria
Guzman, L. E.; Cambier, C.; Cheng, T.-Y.; Naqvi, K. F.; Shiloh, M. U.; Moody, D. B.; Bertozzi, C.
10.1101/2023.11.28.569059 — biochemistry — Posted on 2023-11-29
320 Challenges in estimating species age from phylogenetic trees
Calderon del Cid, C.; Hauffe, T.; Carrillo, J. D.; Warnock, R. C. M.; Silvestro, D.
10.1101/2023.11.19.567731 — evolutionary biology — Posted on 2023-11-28
321 Adaptive gene loss in the common bean pan-genome during range expansion and domestication
Cortinovis, G.; Vincenzi, L.; Anderson, R.; Marturano, G.; Marsh, J. I.; Bayer, P. E.; Rocchetti, L.; Frascarelli, G.; Lanzavecchia, G.; Pieri, A.; Benazzo, A.; Bellucci, E.; Di Vittori, V.; Nanni, L.; Fernandez, J. J. F.; Rossato, M.; Aguilar, O. M.; Morrell, P. L.; Rodriguez, M.; Gioia, T.; Neumann, K.; Diaz, J. C. A.; Gratias-Weill, A.; Klopp, C.; Geffroy, V.; Bitocchi, E.; Delledonne, M.; Edwards, D.; Papa, R.
10.1101/2023.11.23.568464 — evolutionary biology — Posted on 2023-11-28
325 Batch Effects are Causal Effects: Applications in Human Connectomics
Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2023-11-29
328 Two structurally different oomycete lipophilic MAMPs induce distinctive plant immune responses.
Monjil, M. S.; Kato, H.; Ota, S.; Matsuda, K.; Suzuki, N.; Tenhiro, S.; Tatsumi, A.; Pring, S.; Camagna, M.; Suzuki, T.; Tanaka, A.; Terauchi, R.; Sato, I.; Chiba, S.; Kawakita, K.; Ojika, M.; Takemoto, D.
10.1101/2021.10.22.465218 — plant biology — Posted on 2023-11-29
329 Boosting performance of generative diffusion model for molecular docking by training on artificial binding pockets
Voitsitskyi, T.; Bdzhola, V.; Stratiichuk, R.; Koleiev, I.; Ostrovsky, Z.; Vozniak, V.; Khropachov, I.; Henitsoi, P.; Popryho, L.; Zhytar, R.; Yesylevskyy, S. O.; Nafiiev, A.; Starosyla, S.
10.1101/2023.11.22.568238 — bioinformatics — Posted on 2023-11-28
332 An engineered biosensor enables dynamic aspartate measurements in living cells
Davidsen, K.; Marvin, J. S.; Aggarwal, A.; Brown, T. A.; Sullivan, L. B.
10.1101/2023.06.27.546775 — biochemistry — Posted on 2023-11-28
333 The slow evolving genome of the xenacoelomorph worm Xenoturbella bocki
Schiffer, P. H.; Natsidis, P.; Leite, D. J.; Robertson, H.; Lapraz, F.; Marletaz, F.; Fromm, B.; Baudry, L.; Simpson, F.; Hoye, E.; Zakrzewski, A.-C.; Kapli, P.; Hoff, K. J.; Mueller, S.; Marbouty, M.; Marlow, H.; Copley, R. H.; Koszul, R.; Sarkies, P.; Telford, M. J.
10.1101/2022.06.24.497508 — evolutionary biology — Posted on 2023-11-28
335 Combined in vivo and in situ genome-resolved metagenomics reveals novel symbiotic nitrogen fixing interactions between non-cyanobacterial diazotrophs and microalgae
Chandola, U.; Trottier, C.; Gaudin, M.; Lavier Aydat, L. J.; Manirakiza, E.; Menicot, S.; Fischer, E. J.; Louvet, I.; Lacour, T.; Chaumier, T.; Tanaka, A.; Pohnert, G.; Chaffron, S.; Tirichine, L.
10.1101/2022.08.25.505241 — microbiology — Posted on 2023-11-28
338 Ventral hippocampal interneurons govern extinction and relapse of contextual associations
Lacagnina, A. F.; Dong, T. N.; Iyer, R. R.; Khan, S.; Mohamed, M. K.; Clem, R. L.
10.1101/2023.11.28.568835 — neuroscience — Posted on 2023-11-28
340 Visual to default network pathways: A double dissociation between semantic and spatial cognition
Gonzalez Alam, T. R.; Krieger-Redwood, K.; Varga, D.; Gao, Z.; Horner, A. R.; Hartley, T.; Thiebaut de Schotten, M.; Sliwinska, M. W.; Pitcher, D.; Margulies, D. S.; Smallwood, J.; Jefferies, E.
10.1101/2023.11.28.568861 — neuroscience — Posted on 2023-11-28
341 Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice
Nasello, C.; Poppi, L.; Wu, J.; Kowalski, T. F.; Thackray, J. K.; Wang, R.; Persaud, A.; Mahboob, M.; Spaseska, R.; Johnson, C. K.; Gordon, D.; Tissir, F.; Heiman, G. A.; Tischfield, J. A.; Bocarsly, M.; Tischfield, M.
10.1101/2023.11.28.569034 — neuroscience — Posted on 2023-11-28
343 Individual alpha frequency modulates prediction error-driven memory encoding
Jano, S. L.; Chatburn, A.; Cross, Z. R.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.
10.1101/2023.10.25.564081 — neuroscience — Posted on 2023-11-28
344 Back to the future: omnipresence of fetal influence on the human brain through the lifespan
Walhovd, K. B.; Krogsrud, S. K.; Amlien, I. K.; Sorensen, O.; Wang, Y.; Brathen, A. C. S.; Overbye, K.; Kransberg, J.; Mowinckel, A. M.; Magnussen, F.; Herud, M.; Haberg, A. K.; Fjell, A. M.; Vidal-Pineiro, D.
10.1101/2022.12.02.514196 — neuroscience — Posted on 2023-11-28
345 D--hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.
Kula, B.; Antal, B.; Weistuch, C.; Gackiere, F.; Barre, A.; Velado, V.; Hubbard, J. M.; Kukley, M.; Mujica-Parodi, L. R.; Smith, N. A.
10.1101/2023.08.23.554428 — neuroscience — Posted on 2023-11-28
346 Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe
Ouasti, F.; Audin, M.; Freon, K.; Quivy, J.-P.; Tachekort, M.; Cesard, E.; Thureau, A.; Ropars, V.; Varela, P. F.; Moal, G.; Soumana-Amadou, I.; Uryga, A.; Legrand, P.; Andreani, J.; Guerois, R.; Almouzni, G.; Lambert, S. A.; Ochsenbein, F.
10.1101/2023.06.02.543505 — biochemistry — Posted on 2023-11-28
348 Darwin's "neuters" and the evolution of the sex continuum in a superorganism
Oettler, J.; Wallner, T.; Dofka, B.; Heinze, J.; Eichner, N.; Meister, G.; Errbii, M.; Rehli, M.; Gebhard, C.; Schultner, E.
10.1101/2023.11.13.566820 — evolutionary biology — Posted on 2023-11-28
350 Towards a multi-stressor theory for coral reefs in a changing world
Bieg, C.; Valles, H.; Tewfik, A.; Lapointe, B. E.; McCann, K. S.
10.1101/2022.03.22.485402 — ecology — Posted on 2023-11-28
355 A transmission bottleneck for malaria? Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes
Andolina, C.; Graumans, W.; Guelbeogo, M.; Gemert, G.-J. v.; Ramjith, J.; Harouna, S.; Soumanaba, Z.; Stoter, R.; van de Vegte-Bolmer, M.; Pangos, M.; Sinnis, P.; Collins, K.; Staedke, S.; Tiono, A.; Drakeley, C.; Lanke, K.; Bousema, T.
10.1101/2023.08.03.551751 — microbiology — Posted on 2023-11-28
357 A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus
Zhang, Y.; Zhang, M.; Wu, H.; Wang, X.; Zheng, H.; Feng, J.; Wang, J.; Luo, L.; Xiao, H.; Qiao, C.; Li, X.; Zheng, Y.; Huang, W. J.; Wang, Y.; Wang, Y.; Shi, Y.; Feng, J.; Chen, G.
10.1101/2023.09.17.558100 — immunology — Posted on 2023-11-28
358 Gaming expertise induces meso-scale brain plasticity and efficiency mechanisms as revealed by whole-brain modeling
Coronel-Oliveros, C.; Medel, V.; Orellana, S.; Rodino, J.; Lehue, F.; Cruzat, J.; Tagliazucchi, E.; Brzezicka, A.; Orio, P.; Kowalczyk-Grebska, N.; Ibanez, A.
10.1101/2023.08.21.554072 — neuroscience — Posted on 2023-11-28
362 Developmental pyrethroid exposure disrupts molecular pathways for circadian rhythms and MAP kinase in mouse brain.
Nguyen, J. H.; Curtis, M. A.; Imami, A. S.; Ryan, W. G.; Alganem, K.; Neifer, K. L.; Saferin, N.; Nawor, C. N.; Kistler, B. P.; Miller, G. W.; Shukla, R.; McCullumsmith, R. E.; Burkett, J. P.
10.1101/2023.08.28.555113 — neuroscience — Posted on 2023-11-28
364 Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model
Blaeser, A. S.; Zhao, J.; Sugden, A. U.; Carneiro-Nascimento, S.; Andermann, M. L.; Levy, D.
10.1101/2023.07.31.549838 — neuroscience — Posted on 2023-11-28
366 Intraspecific genetic variation is critical to robust toxicological predictions of aquatic contaminants
Shahmohamadloo, R. S.; Rudman, S. M.; Clare, C. I.; Westrick, J. A.; Wang, X.; De Meester, L.; Fryxell, J. M.
10.1101/2023.06.06.543817 — pharmacology and toxicology — Posted on 2023-11-28
367 Rupture Strength of Living Cell Monolayers
Duque, J.; Bonfanti, A.; Fouchard, J.; Baldauf, L.; Azenha, S. R.; Ferber, E.; Harris, A.; Barriga, E. H.; Kabla, A.; Charras, G.
10.1101/2023.01.05.522736 — biophysics — Posted on 2023-11-28
369 Towards quantitative DNA Metabarcoding: A method to overcome PCR amplification bias
Moinard, S.; Piau, D.; Laporte, F.; Rioux, D.; Taberlet, P.; Gonindard-Melodelima, C.; Coissac, E.
10.1101/2023.10.03.560640 — ecology — Posted on 2023-11-28
370 Effects of Food Addition and Helminth Removal on Space Use and Spatial Overlap in Wild Rodent Populations
Mistrick, J.; Veitch, J. S. M.; Kitchen, S. M.; Clague, S.; Newman, B. C.; Hall, R. J.; Budischak, S. A.; Forbes, K. M.; Craft, M. E.
10.1101/2022.12.22.521674 — ecology — Posted on 2023-11-28
371 The protein map of the protozoan parasite Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum during growth phase transition and temperature stress
Mule, S. N.; Saad, J. S.; Sauter, I. P.; Fernandes, L. R.; de Oliveira, G. S.; Quina, D.; Tano, F. T.; Brandt-Almeida, D.; Padron, G.; Stolf, B. S.; Larsen, M. R.; Cortez, M.; Palmisano, G.
10.1101/2023.11.27.568882 — microbiology — Posted on 2023-11-28
377 Enhanced detection of RNA modifications and mappability with high-accuracy nanopore RNA basecalling models
Diensthuber, G.; Pryszcz, L.; Llovera, L.; Lucas, M. C.; Delgado-Tejedor, A.; Cruciani, S.; Roignant, J.-Y.; Begik, O.; Novoa, E. M.
10.1101/2023.11.28.568965 — genomics — Posted on 2023-11-28
379 Tau P301L mutation promotes core 4R tauopathy fibril fold through near-surface water structuring and conformational rearrangement
Vigers, M.; Lobo, S.; Najafi, S.; Dubose, A.; Tsay, K.; Ganguly, P.; Longhini, A. P.; Jin, Y.; Buratto, S. K.; Kosik, K. S.; Shell, M. S.; Shea, J.-E.; Han, S.
10.1101/2023.11.28.568818 — biophysics — Posted on 2023-11-28
381 A Global Transcriptional Atlas of the Effect of Sleep Deprivation in the Mouse Frontal Cortex
Ford, K.; Zuin, E.; Righelli, D.; Medina, E.; Schoch, H.; Singletary, K.; Muheim, C.; Frank, M. G.; Hicks, S.; Risso, D.; Peixoto, L.
10.1101/2023.11.28.569011 — neuroscience — Posted on 2023-11-28
384 Nuclear GSH import precedes coordinated cell cycle changes during regeneration
Lee, L. R.; Guillotin, B.; Hutchison, C.; Desvoyes, B.; Gutierrez, C.; Birnbaum, K. D.
10.1101/2023.11.28.569014 — plant biology — Posted on 2023-11-28
386 Regulators of health and lifespan extension in genetically diverse mice on dietary restriction
Di Francesco, A.; Deighan, A. G.; Litichevskiy, L.; Chen, Z.; Luciano, A.; Robinson, L.; Garland, G.; Donato, H.; Schott, W.; Wright, K. M.; Raj, A.; Prateek, G. V.; Mullis, M.; Hill, W.; Zediel, M.; Peters, L.; Harding, F.; Botstein, D.; Korstanje, R.; Thaiss, C.; Freund, A.; Churchill, G. A.
10.1101/2023.11.28.568901 — genetics — Posted on 2023-11-28
387 Prioritization of The Zinc finger domain within BCL11A gene by the Amelioration capability of hemoglobinopathies using CRISPR-Cas9 technology
Mumtaz, K.; Hussain, I.; Iftikhar, F.; Rehman, F. u.; Muhammad, J.; Farooq, S.; Hassan, H.; Ottmann, O. G.; Mian, A. A.
10.1101/2023.11.28.568974 — molecular biology — Posted on 2023-11-28
388 The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress
O'Leary, D. R.; Hansen, A. R.; Fingerman, D. F.; Tran, T. A.; Harris, B. R.; Hayer, K. E.; DeWeerd, R. A.; Tennekoon, M.; Meroni, A.; Szeto, J.; Weitzman, M. D.; Bednarski, J. J.; Shalem, O.; Vindigni, A.; Green, A. M.
10.1101/2023.11.28.568952 — molecular biology — Posted on 2023-11-28
389 A rolling circle-replicating plasmid as an Inovirus phage satellite
Schmid, N. E.; Brandt, D.; Walasek, C.; Rolland, C.; Wittmann, J.; Müsken, M.; Kalinowski, J.; Thormann, K. M.
10.1101/2023.11.28.569023 — microbiology — Posted on 2023-11-28
391 High-throughput and scalable single cell proteomics identifies over 5000 proteins per cell
Ye, Z.; Sabatier, P.; Hoeven, L.; Phlairaharn, T.; Hartlmayr, D.; Izaguirre, F.; Seth, A.; Joshi, H.; Bekker-Jensen, D.; Bache, N.; Olsen, J. V.
10.1101/2023.11.27.568953 — systems biology — Posted on 2023-11-28
394 A library of reporters of the global regulators of gene expression of Escherichia coli
Dash, S.; Jagadeesan, R.; Baptista, I. S. C.; Chauhan, V.; Kandavalli, V.; Oliveira, S. M. D.; Ribeiro, A. S.
10.1101/2023.11.28.568972 — synthetic biology — Posted on 2023-11-28
395 High-yield enzymatic synthesis of mono- and trifluorinated alanine enantiomers
Nieto-Dominguez, M.; Sako, A.; Enemark-Rasmussen, K.; Held Gotfredsen, C.; Rago, D.; Nikel, P. I.
10.1101/2023.11.28.569005 — synthetic biology — Posted on 2023-11-28
396 Allosteric Competition and Inhibition in AMPA Receptors
Hale, W. D.; Romero, A. M.; Gonzalez, C. U.; Jayaraman, V.; Lau, A. Y.; Huganir, R. L.; Twomey, E. C.
10.1101/2023.11.28.569057 — biophysics — Posted on 2023-11-28
398 A biodegradable "one-for-all" nanoparticle for multimodality imaging and enhanced photothermal treatment of breast cancer
Hsu, J. C.; Barragan, D.; Tward, A. E.; Hajfathalian, M.; Amirshaghaghi, A.; Mossburg, K. J.; Rosario-Berrios, D. N.; Bouche, M.; Andrianov, A. K.; Delikatny, E. J.; Cormode, D. P.
10.1101/2023.11.28.568885 — bioengineering — Posted on 2023-11-28
399 Tripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca2+ channel modulate its β-adrenergic regulation
Oz, S.; Sharon, T.; Surbramaniam, S.; Pallien, T.; Katz, M.; Tsemakhovich, V.; Tripathy, D. R.; Sasson, G.; Chomsky-Hecht, O.; Vysochek, L.; Schulz, M.; Fecher-Trost, C.; Zuhlke, K.; Bertinetti, D.; Herberg, F. W.; Keren-Raifman, T.; Flockerzi, V.; Hirsch, J. A.; Klussmann, E.; Weiss, S.; Dascal, N.
10.1101/2023.11.28.564875 — biochemistry — Posted on 2023-11-28
403 Identification of a novel, tunable interface in the S.pombe HP1 protein, Swi6, that underpins epigenetic inheritance.
Ames, A.; Seman, M.; Larkin, A.; Raiymbek, G.; Chen, Z.; Levashkevich, A.; Biteen, J. S.; Ragunathan, K.
10.1101/2023.11.28.569027 — molecular biology — Posted on 2023-11-28
404 H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs
Krug, B.; Hu, B.; Chen, H.; Ptack, A.; Chen, X.; Gretarsson, K. H.; Deshmukh, S.; Kabir, N.; Faria Andrade, A.; Jabbour, E.; Harutyunyan, A. S.; Lee, J. J. Y.; Hulswit, M.; Faury, D.; Russo, C.; Xu, X.; Johnston, M. J.; Baguette, A.; Dahl, N. A.; Weil, A. G.; Ellezam, B.; Dali, R.; Blanchette, M.; Wilson, K.; Garcia, B. A.; Soni, R. K.; Gallo, M.; Taylor, M. D.; Kleinman, C. L.; Majewski, J.; Jabado, N.; Lu, C.
10.1101/2023.11.28.567931 — molecular biology — Posted on 2023-11-28
409 DNA methylation by CcrM contributes to genome maintenance in the Agrobacterium tumefaciens plant pathogen
Martin, S.; Fournes, F.; Ambrosini, G.; Iseli, C.; BOJKOWSKA, K.; Marquis, J.; Guex, N.; Collier, J.
10.1101/2023.11.28.569018 — microbiology — Posted on 2023-11-28
410 BCG vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow
Sun, S. J.; Aguirre-Gamboa, R.; de Bree, C. J.; Sanz, J.; Dumaine, A.; Joosten, L. A.; Divangahi, M.; Netea, M.; Barreiro, L. B.
10.1101/2023.11.28.569076 — immunology — Posted on 2023-11-28
412 Microfluidic device for simple diagnosis of plant growth condition by detecting miRNAs from filtered plant extracts
Kawakatsu, Y.; Okada, R.; Hara, M.; Tsutsui, H.; Yanagisawa, N.; Higashiyama, T.; Arima, A.; Baba, Y.; Kurotani, K.-i.; Notaguchi, M.
10.1101/2023.11.27.568951 — plant biology — Posted on 2023-11-28
413 Stress Knowledge Map: A knowledge graph resource for systems biology analysis of plant stress responses
Bleker, C.; Ramsak, Z.; Bittner, A.; Podpecan, V.; Zagorscak, M.; Wurzinger, B.; Baebler, S.; Petek, M.; Kriznik, M.; van Dieren, A.; Gruber, J.; Afjehi-Sadat, L.; Zupanic, A.; Teige, M.; Vothknecht, U. C.; Gruden, K.
10.1101/2023.11.28.568332 — plant biology — Posted on 2023-11-28
415 Combinatorial optimization of pathway, process and media for the production of p-coumaric acid by Saccharomyces cerevisiae
Moreno Paz, S.; van der Hoek, R.; Eliana, E.; Martins dos Santos, V. A. P.; Schmitz, J.; Suarez-Diez, M.
10.1101/2023.11.28.568970 — bioengineering — Posted on 2023-11-28
416 Bioorthogonal metabolic labeling of the virulence factor phenolic glycolipid in mycobacteria
Guzman, L. E.; Cambier, C.; Cheng, T.-Y.; Naqvi, K. F.; Shiloh, M. U.; Moody, D. B.; Bertozzi, C.
10.1101/2023.11.28.569059 — biochemistry — Posted on 2023-11-28
417 A unique chaperoning mechanism in Class A JDPs recognizes and stabilizes mutant p53.
Zoltsman, G.; Dang, T. L.; Kuchersky, M.; Faust, O.; Silva, M. S.; Ilani, T.; Wentink, A. S.; Bukau, B.; Rosenzweig, R.
10.1101/2023.11.28.568993 — biochemistry — Posted on 2023-11-28
422 Enrichable consortia of microbial symbionts degrade macroalgal polysaccharides in Kyphosus fish
Oliver, A.; Podell, S.; Wegley Kelly, L.; Sparagon, W. J.; Plominsky, A. M.; Nelson, R. S.; Laurens, L. M.; Augyte, S.; Sims, N. A.; Nelson, C. E.; Allen, E. E.
10.1101/2023.11.28.568905 — microbiology — Posted on 2023-11-28
423 Interpretable Inflammation Landscape of Circulating Immune cells
Jimenez-Gracia, L.; Maspero, D.; Aguilar-Fernandez, S.; Craighero, F.; Ruiz, S.; Marchese, D.; Caratu, G.; Elosua-Bayes, M.; Abdalfatah, M.; Sanzo-Machuca, A.; M. Corraliza, A.; Massoni-Badosa, R.; A. Tran, H.; Normand, R.; Nestor, J.; Hong, Y.; Kole, T.; van der Velde, P.; Alleblas, F.; Pedretti, F.; Aterido, A.; Banchero, M.; Soriano, G.; Roman, E.; van den Berge, M.; Salas, A.; Carrascosa, J. M.; Fernandez Nebro, A.; Domenech, E.; Canete, J.; Tornero, J.; Perez-Gisbert, J.; Choy, E.; Girolomoni, G.; Siegmund, B.; Julia, A.; Serra, V.; Elosua, R.; Tejpar, S.; Vidal, S.; Nawijn, M. C.; Marsal
10.1101/2023.11.28.568839 — immunology — Posted on 2023-11-28
424 Investigating the validity and interpretability of longitudinal brain age underlying cognition in Asian children and older adults
Cheng, S. F.; Yue, W. L.; Ng, K. K.; Qian, X.; Liu, S.; Tan, T. W. K.; Nguyen, K.-N.; Leong, R. L. F.; Hilal, S.; Cheng, C.-Y.; Law, E. C.; Gluckman, P. D.; Chen, C. L.-H.; Meaney, M. J.; Chee, M.; Yeo, B. T. T.; Zhou, J. H.
10.1101/2023.11.27.568184 — neuroscience — Posted on 2023-11-28
426 Brain network connectivity underlying remission in early psychosis: a whole brain model approach
Mana, L.; Lopez-Gonzalez, A.; Aleman Gomez, Y.; Baumann, P.; Jenni, R.; Alameda, L.; Abrahamyan Empson, L.; Klauser, P.; Conus, P.; Hagmann, P.; Vila Vidal, M.; Deco, G.
10.1101/2023.11.28.568844 — neuroscience — Posted on 2023-11-28
427 Adaptive remodeling of rat adrenomedullary stimulus-secretion coupling in response to a chronic hypertensive environment
Paille, V.; Park, J.; Toutain, B.; Bourreau, J.; Fontanaud, P.; De Nardi, F.; Gabillard-Lefort, C.; Breard, D.; Guilet, D.; Henrion, D.; Legros, C.; Guerineau, N. C.
10.1101/2023.11.28.568973 — physiology — Posted on 2023-11-28
428 Epiregulon: Inference of single-cell transcription factor activity to dissect mechanisms of lineage plasticity and drug response
Wlodarczyk, T.; Lun, A.; Wu, D.; Menon, S.; Toneyan, S.; Seidel, K.; Wang, L.; Tan, J.; Chen, S.-Y.; Keyes, T.; Chlebowski, A.; Guo, Y.; Metcalfe, C.; Hafner, M.; Siebel, C. W.; Corces, M. R.; Yauch, R.; Xie, S.; Yao, X.
10.1101/2023.11.27.568955 — bioinformatics — Posted on 2023-11-28
432 In-bore MRI-compatible Transrectal Ultrasound and Photoacoustic Imaging
Murakami, R.; Wang, Y.; Lesniak, W.; Tsumura, R.; Tang, Y.; Tsunoi, Y.; Nycz, C. J.; Pomper, M. G.; Fischer, G. S.; Zhang, H. K.
10.1101/2023.11.27.568947 — bioengineering — Posted on 2023-11-28
434 Digital twinning of cardiac electrophysiology for congenital heart disease
Salvador, M.; Kong, F.; Peirlinck, M.; Parker, D.; Chubb, H.; Dubin, A.; Marsden, A.
10.1101/2023.11.27.568942 — bioengineering — Posted on 2023-11-28
438 Cell-Specific Transposable Element Gene Expression Analysis Identifies Associations with Systemic Lupus Erythematosus Phenotypes
Cutts, Z.; Patterson, S.; Maliskova, L.; Taylor, K. E.; Ye, C. J.; Dall'Era, M.; Yazdany, J.; Criswell, L.; Fragiadakis, G. K.; Langelier, C.; Capra, J. A.; Sirota, M.; Lanata, C.
10.1101/2023.11.27.567477 — molecular biology — Posted on 2023-11-28
439 Codon optimality modulates protein output by tuning translation initiation
Lyons, E. F.; Devanneaux, L. C.; Muller, R. Y.; Freitas, A. V.; Meacham, Z. A.; McSharry, M. V.; Trinh, V. N.; Rogers, A. J.; Ingolia, N. T.; Lareau, L. F.
10.1101/2023.11.27.568910 — molecular biology — Posted on 2023-11-28
442 Altered structural connectivity and functional brain dynamics in individuals with heavy alcohol use
Singleton, S. P.; Velidi, P.; Schilling, L.; Luppi, A. I.; Jamison, K.; Parkes, L.; Kuceyeski, A.
10.1101/2023.11.27.568762 — neuroscience — Posted on 2023-11-28
447 Medicinal chemistry lens on patent data in SureChEMBL
Gadiya, Y.; Shetty, S.; Hofmann-Apitius, M.; Gribbon, P.; Zaliani, A.
10.1101/2023.11.27.568822 — bioinformatics — Posted on 2023-11-28
450 Identifying Naturalistic Movies from Human Brain Activity with High-Density Diffuse Optical Tomography
Markow, Z. E.; Tripathy, K.; Svoboda, A. M.; Schroeder, M. L.; Rafferty, S. M.; Richter, E. J.; Eggebrecht, A. T.; Anastasio, M. A.; Chevillet, M. A.; Mugler, E. M.; Naufel, S. N.; Yin, A.; Trobaugh, J. W.; Culver, J. P.
10.1101/2023.11.27.566650 — bioengineering — Posted on 2023-11-28
452 Epigenomic signatures as circulating and predictive biomarkers in sarcomatoid renal cell carcinoma
El Zarif, T.; Semaan, K.; Eid, M.; Sep, J.-H.; Semaan, S. G.; Davidsohn, M. P.; Fortunato, B.; Canniff, J.; Nassar, A. H.; Abou Alaiwi, S.; Bakouny, Z.; Lakshmi, G.; Savigano, H.; Lyons, K.; Matar, S.; Ali, A.; Saad, E.; Saliby, R. M.; Cordeiro, P.; Zhang, Z.; El Ahmar, N.; Nabil Laimon, Y.; Labaki, C.; Shah, V.; Freeman, D.; O'Toole, J.; Lee, G.-S. M.; Hwang, J.; Pomerantz, M.; Signoretti, S.; Xie, W.; Berchuck, J. E.; Viswanathan, S. R.; Van Allen, E. M.; Braun, D. A.; Choueiri, T. K.; Freedman, M. L.; Baca, S. C.
10.1101/2023.11.27.568827 — genomics — Posted on 2023-11-28
453 MetaVision3D: Automated framework for the Generation of Spatial Metabolome Atlas in 3D
Ma, X.; Shedlock, C. J.; Medina, T.; Ribas, R.; Clarke, H.; Hawkinson, T.; Dande, P.; Wu, L.; Burke, S. N.; Merritt, M.; Vander Kooi, C.; Gentry, M.; Yadav, N.; Chen, L.; Sun, R. C.
10.1101/2023.11.27.568931 — neuroscience — Posted on 2023-11-28
454 Terminally differentiated effector memory T cells associate with cognitive and AD-related biomarkers in an aging-based community cohort
Winford, E. D.; Lutshumba, J.; Martin, B. J.; Wilcock, D. M.; Jicha, G. A.; Nikolajczyk, B.; Stowe, A. M.; Bachstetter, A. D.
10.1101/2023.11.27.568812 — neuroscience — Posted on 2023-11-28
459 Male cuticular pheromones stimulate removal of the mating plug and promote re-mating through pC1 neurons in Drosophila females
Yun, M.; Kim, D.-H.; Ha, T. S.; Lee, K.-M.; Park, E.; Dweck, H. K. M.; Knaden, M.; Hansson, B. S.; Kim, Y.-J.
10.1101/2023.11.28.568981 — neuroscience — Posted on 2023-11-28
463 Cortical ductility governs cell-cell adhesion mechanics
Arora, A.; Rizvi, M. S.; Grenci, G.; Dilasser, F.; Fu, C.; Ganguli, M.; Vaishnavi, S.; Paramsivam, K.; Budnar, S.; Noodstra, I.; Yap, A.; Viasnoff, V.
10.1101/2023.11.28.568975 — cell biology — Posted on 2023-11-28
464 Heme biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue
Duerre, D. J.; Hansen, J. K.; John, S.; Jen, A.; Carrillo, N.; Bui, H.; Bao, Y.; Fabregat, M.; Overmyer, K.; Shishkova, E.; Keller, M. P.; Anderson, R. A.; Cryns, V. L.; Attie, A. D.; Coon, J.; Fan, J.; Galmozzi, A.
10.1101/2023.11.28.568893 — cell biology — Posted on 2023-11-28
466 Reversal of pulmonary veno-occlusive disease phenotypes by inhibition of the integrated stress response
Prabhakar, A.; Kumar, R.; Wadhwa, M.; Ghatpande, P.; Zhang, J.; Zhao, Z.; Lizama, C. O.; Kharbikar, B. N.; Graf, S.; Treacy, C. M.; Morrell, N. W.; Graham, B. B.; Lagna, G.; Hata, A.
10.1101/2023.11.27.568924 — cell biology — Posted on 2023-11-28
470 Microbial community-scale metabolic modeling predicts personalized short chain fatty acid production profiles in the human gut.
Quinn-Bohmann, N.; Wilmanski, T.; Ramos Sarmiento, K.; Levy, L.; Lampe, J.; Gurry, T.; Rappaport, N.; Ostrem, E. M.; Venturelli, O. S.; Diener, C.; Gibbons, S. M.
10.1101/2023.02.28.530516 — systems biology — Posted on 2023-11-28
471 DIGEST: An online tool for designing of multiple reaction monitoring assays
gautam, p.; Singh, P.; Mrinal, ; Bhaskar, A.; Sacher, S.; Dagar, Y.; Basak, T.; Sengupta, S.; Ray, A.
10.1101/2023.11.27.568790 — bioinformatics — Posted on 2023-11-28
472 Ancient AMY1 gene duplications primed the amylase locus for adaptive evolution upon the onset of agriculture
Yilmaz, F.; Karageorgiou, C.; Kim, K.; Pajic, P.; Beck, C. R.; Human Genome Structural Variation Consortium, ; Torregrossa, A.-M.; Lee, C.; Gokcumen, O.
10.1101/2023.11.27.568916 — evolutionary biology — Posted on 2023-11-28
474 Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model
Llambrich, S.; Tielemans, B.; Saliën, E.; Atzori, M.; Wouters, K.; Van Bulck, V.; Platt, M.; Vanherp, L.; Gallego Fernandez, N.; Grau de la Fuente, L.; Poptani, H.; Verlinden, L.; Himmelreich, U.; Croitor, A.; Attanasio, C.; Callaerts-Vegh, Z.; Gsell, W.; Martinez-Abadias, N.; Vande Velde, G.
10.1101/2023.07.31.551282 — systems biology — Posted on 2023-11-28
477 Synergistic control of chloroplast biogenesis by MYB-related and Golden2-like transcription factors
Frangedakis, E.; Yelina, N.; Billakurthi, K.; Schreier, T. B.; Dickinson, P. J.; Tomaselli, M.; Haseloff, J.; Hibberd, J. M.
10.1101/2023.08.11.552970 — plant biology — Posted on 2023-11-28
478 Human skeletal muscle fiber heterogeneity beyond myosin heavy chains
Moreno-Justicia, R.; Van der Stede, T.; Stocks, B.; Laitila, J.; Seaborne, R. A.; Van de Loock, A.; Lievens, E.; Samodova, D.; Marin-Arraiza, L.; Dmytriyeva, O.; Van Vossel, K.; Yigit, N.; Anckaert, J.; Weyns, A.; Van Thienen, R.; Sahl, R. E.; Zanoteli, E.; Wierer, M.; Mestdagh, P.; Lawlor, M. W.; Vandesompele, J.; Ochala, J.; Hostrup, M.; Derave, W.; Deshmukh, A. S.
10.1101/2023.09.07.556665 — physiology — Posted on 2023-11-28
479 Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations
Zhou, X.; Wang, Z. J.; Camps, J.; Tomek, J.; Santiago, A.; Quintanas, A.; Vazquez, M.; Vaseghi, M.; Rodriguez, B.
10.1101/2022.02.15.480392 — bioengineering — Posted on 2023-11-28
483 Finite Sample Adjustments for Average Equivalence Testing
Boulaguiem, Y.; Quartier, J.; Lapteva, M.; Kalia, Y. N.; Victoria-Feser, M.-P.; Guerrier, S.; Couturier, D.-L.
10.1101/2023.03.11.532179 — pharmacology and toxicology — Posted on 2023-11-28
488 Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm
Wu, Z.; Zheng, G.; Sun, Y.; Dong, X.; Wang, Y.; Li, H.; Niu, Y.; Huang, Z.; Hu, J.; Liu, Z.
10.1101/2023.11.12.566742 — genomics — Posted on 2023-11-28
494 A rigorous benchmarking of alignment-based HLA callers for RNA-seq data
Yu, D.; Ayyala, R.; Sadek, S. H.; Chittampalli, L.; Farooq, H.; Jung, J.; Nahid, A. A.; Boldirev, G.; Hu, J.; Alomair, R.; Park, S.; Nguyen, A. D.; Zelikovsky, A.; Mancuso, N.; Joo, J. W.; Thompson, R. F.; Alachkar, H.; Mangul, S.
10.1101/2023.05.22.541750 — bioinformatics — Posted on 2023-11-28
496 Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis
Homan, K.; Onodera, T.; Hanamatsu, H.; Furukawa, J.-i.; Momma, D.; Matsuoka, M.; Iwasaki, N.
10.1101/2023.09.28.560052 — cell biology — Posted on 2023-11-28
497 Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell identity and function.
Lopez-Noriega, L.; Callingham, R. M.; Martinez-sanchez, A.; Nawaz, S.; Pizza, G.; Haberman, N.; Cvetesic, N.; Nguyen-Tu, M.-S.; Lenhard, B.; Marchetti, P.; Piemonti, L.; de Koning, E. J. P.; Shapiro, A. M. J.; Johnson, P. R.; Leclerc, I.; HASTOY, B.; Gauthier, B. R.; Pullen, T. J.; Rutter, G. A.
10.1101/2020.07.17.209015 — cell biology — Posted on 2023-11-28
498 Precision Proteoform Design for 4R Tau Isoform Selective Templated Aggregation
Longhini, A. P.; DuBose, A.; Lobo, S.; Vijayan, V.; Bai, Y.; Keane, E.; Sala-Jarque, J.; Nikitina, A.; Carrettiero, D.; Unger, M.; Sclafani, O.; Fu, V.; Vigers, M.; Buee, L.; Landrieu, I.; Shell, S.; Shea, J. E.; Han, S.; Kosik, K. S.
10.1101/2023.08.31.555649 — molecular biology — Posted on 2023-11-28
499 Frontal cortex norepinephrine, serotonin, and dopamine dynamics in an innate fear-reward behavioral model
Yang, J.-h.; Basu, A.; Liu, R.-J.; Staszko, S. M.; Yu, A. L.; Rondeau, J.; Glaeser-Khan, S.; Li, Y.; Che, A.; Kaye, A. P.
10.1101/2023.11.27.568929 — neuroscience — Posted on 2023-11-28
501 Deep Mutational Scanning in Disease-related Genes with Saturation Mutagenesis-Reinforced Functional Assays (SMuRF)
Ma, K.; Ng, K. K.; Huang, S.; Lake, N. J.; Xu, J.; Lek, A.; Ge, L.; Woodman, K. G.; Koczwara, K. E.; Ho, V.; O'Connor, C. L.; Joseph, S.; Brindley, M. A.; Campbell, K. P.; Lek, M.
10.1101/2023.07.12.548370 — genetics — Posted on 2023-11-27
502 Chondrodysplasia-inducing COL2A1 p.Gly1170Ser causes an ER storage defect without associated unfolded protein response in a human cartilage model
Yammine, K. M.; Abularach, S. M.; Kim, S.-y.; Bikovtseva, A. A.; Lilianty, J.; Butty, V. L.; Schiavoni, R. P.; Bateman, J. F.; Lamande, S. R.; Shoulders, M. D.
10.1101/2023.10.19.562780 — genetics — Posted on 2023-11-27
503 Metabolic and Neurobehavioral Disturbances Induced by Purine Recycling Deficiency in Drosophila
Petitgas, C.; Seugnet, L.; Dulac, A.; Matassi, G.; Mteyrek, A.; Fima, R.; Strehaiano, M.; Dagorret, J.; Cherif-Zahar, B.; Marie, S.; Ceballos-Picot, I.; Birman, S.
10.1101/2023.06.23.546306 — neuroscience — Posted on 2023-11-27
505 Piezo1 stretch-activated channel activity differs between bone marrow-derived and cardiac tissue-resident macrophages
Simon-Chica, A.; Klesen, A.; Emig, R.; Chan, A.; Gruen, D.; Lother, A.; Hilgendorf, I.; Ravens, U.; Kohl, P.; Schneider-Warme, F.; Peyronnet, R.
10.1101/2023.11.27.568894 — biophysics — Posted on 2023-11-27
510 Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse
Lu, Y.; Walji, T.; Ravaux, B.; Pandey, P.; Li, B.; Lam, K. H.; Zhang, R.; Goldhamer, D. J.; Li, R.; Schmidtke, D. W.; Pan, D.; Chen, E. H.
10.1101/2023.11.27.568897 — cell biology — Posted on 2023-11-27
512 Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation
Mitchell, W.; Goeminne, L. J. E.; Tyshkovskiy, A.; Zhang, S.; Chen, J. Y.; Paulo, J. A.; Pierce, K. A.; Choy, A. H.; Clish, C. B.; Gygi, S. P.; Gladyshev, V. N.
10.1101/2023.06.30.546730 — molecular biology — Posted on 2023-11-27
513 Generation and evaluation of protease inhibitor-resistant SARS-CoV-2 strains
Bouzidi, H. S.; Driouich, J.-S.; Klitting, R.; Bernadin, O.; Piorkowski, G.; Amaral, R.; Fraisse, L.; Mowbray, C. E.; Scandale, I.; Escudie, F.; Chatelain, E.; de Lamballerie, X.; Nougairede, A.; Touret, F.
10.1101/2023.11.22.568013 — microbiology — Posted on 2023-11-27
515 The integration of tactile and proprioceptive signals to achieve haptic object perception
Dogruoz, R. E.; Shelchkova, N. S.; Sheets, D. E.; Greenspon, C. M.; Bensmaia, S. J.
10.1101/2023.11.27.568836 — neuroscience — Posted on 2023-11-27
518 Inferring control objectives in a virtual balancing task in humans and monkeys
Sadeghi, M.; Sharif Razavian, R.; Bazzi, S.; Chowdhury, R. H.; Batista, A. P.; Loughlin, P. J.; Sternad, D.
10.1101/2023.05.02.539055 — neuroscience — Posted on 2023-11-27
519 Towards Generalizability and Robustness in Biological Object Detection in Electron Microscopy Images
GIANNIOS, K.; Chaurasia, A.; Bueno, C.; Riesterer, J. L.; Pagano, L.; Lo, T. P.; Thibault, G.; Gray, J. W.; Song, X.; DeLaRosa, B.
10.1101/2023.11.27.568889 — bioengineering — Posted on 2023-11-27
523 The protein map of the protozoan parasite Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum during growth phase transition and temperature stress
Mule, S. N.; Saad, J. S.; Sauter, I. P.; Fernandes, L. R.; de Oliveira, G. S.; Quina, D.; Tano, F. T.; Brandt-Almeida, D.; Stolf, B. S.; Larsen, M. R.; Cortez, M.; Palmisano, G.
10.1101/2023.11.27.568882 — microbiology — Posted on 2023-11-27
524 TRIBAL: Tree Inference of B cell Clonal Lineages
Weber, L. L.; Reiman, D.; Roddur, M. S.; Qi, Y. L.; El-Kebir, M.; Khan, A. A.
10.1101/2023.11.27.568874 — immunology — Posted on 2023-11-27
525 XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against emerging SARS-CoV-2 variants
Wang, Q.; Guo, Y.; Bowen, A.; Mellis, I. A.; Valdez, R.; Gherasim, C.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2023.11.26.568730 — immunology — Posted on 2023-11-27
532 Random forest classifiers trained on simulated data enable accurate short read-based genotyping of structural variants in the alpha globin region at Chr16p13.3
Hansen, N. F.; Wang, X.; Tegegn, M. B.; Liu, Z.; Gouveia, M. H.; Hill, G.; Lin, J. C.; Okulosubo, T.; Shriner, D.; Thein, S. L.; Mullikin, J. C.
10.1101/2023.11.27.568683 — bioinformatics — Posted on 2023-11-27
533 Sequence-based drug design using transformers
Zhang, S.; Huo, D.; Horne, R. I.; Qi, Y.; Ojeda, S. P.; Yan, A.; Vendruscolo, M.
10.1101/2023.11.27.568880 — bioinformatics — Posted on 2023-11-27
535 Evolution-guided large language model is a predictor of virus mutation trends
Nie, Z.; Liu, X.; Chen, J.; Wang, Z.; Liu, Y.; Si, H.; Dong, T.; Xu, F.; Song, G.; Wang, Y.; Zhou, P.; Gao, W.; Tian, Y.
10.1101/2023.11.27.568815 — bioinformatics — Posted on 2023-11-27
538 Microencapsulation of mesenchymal stromal cells in covalent alginate hydrogels for cell therapy
Ambrosino, M.; Nativel, F.; Boyer, C.; Lagneau, N.; Loll, F.; Halgand, B.; Djouad, F.; Renard, D.; Tessier, A.; Guicheux, J.; Delplace, V.; Le Visage, C.
10.1101/2023.11.27.568852 — bioengineering — Posted on 2023-11-27
540 Modulation of human kinase activity through direct interaction with SARS-CoV-2 proteins
Halwachs, B.; Moesslacher, C. S.; Kohlmayr, J. M.; Fasching, S.; Masser, S.; Choteau, S. A.; Zanzoni, A.; Stelzl, U.
10.1101/2023.11.27.568816 — biochemistry — Posted on 2023-11-27
544 Drivers of population dynamics of at-risk populations change with pathogen arrival
Grimaudo, A. T.; Hoyt, J. R.; King, R. A.; Toomey, R. S.; Simpson, C.; Holliday, C.; Silvis, A.; Doyle, R. T.; Kath, J. A.; Armstrong, M. P.; Brack, V.; Reynolds, R. J.; Williamson, R. H.; Turner, G. G.; Kuczynska, V.; Meyer, J. J.; Jansky, K.; Herzog, C. J.; Hopkins, S. R.; Langwig, K. E.
10.1101/2023.11.27.568870 — ecology — Posted on 2023-11-27
546 Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging.
Dutta, N.; Gerke, J. A.; Ordon, S. F.; Morris, J. D.; Hruby, A.; Torres, T. C.; Shemtov, S.; Clark, J. G.; Chang, M. C.; Shaghasi, H.; Ray, M. N.; Averbukh, M.; Hoang, S.; Oorloff, M.; Alcala, A.; Vega, M.; Mehta, H. H.; Max, T. A.; Crews, P.; Vermulst, M.; Garcia, G.; Johnson, T. A.; Higuchi-Sanabria, R.
10.1101/2023.11.27.568896 — cell biology — Posted on 2023-11-27
548 Safe plant Hsp90 adjuvants elicit an effective immune response against SARS-CoV2 derived RBD antigen
Ramos-Duarte, V. A.; Orlowski, A.; Jaquenod de Giusti, C.; Corigliano, M. G.; Legarralde, A.; Mendoza-Morales, L. F.; Atela, A.; Sanchez, M. A.; Sander, V. A.; Angel, S. O.; Clemente, M.
10.1101/2023.11.25.568642 — molecular biology — Posted on 2023-11-27
549 The antiviral potential of the antiandrogen enzalutamide and the viral-androgen interplay in seasonal coronaviruses
Ogunjinmi, O. D.; Abdullahi, T.; Somji, R.-A.; Bevan, C. L.; Barclay, W. S.; Temperton, N. J.; Brooke, G. N.; Giotis, E. S.
10.1101/2023.11.25.568685 — microbiology — Posted on 2023-11-27
550 The second messenger c-di-AMP controls natural competence via ComFB signaling protein
Samir, S.; Doello, S.; Zimmer, E.; Haffner, M.; Enkerlin, A. M.; Mueller, T.; Dengler, L.; Lambidis, S. P.; Sivabalasarma, S.; Albers, S.-V.; Selim, K. A.
10.1101/2023.11.27.568819 — microbiology — Posted on 2023-11-27
551 Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.
Lercher, A.; Cheong, J.-G.; Jiang, C.; Hoffmann, H.-H.; Ashbrook, A. W.; Yin, Y. S.; Quirk, C.; DeGrace, E. J.; Chiriboga, L.; Rosenberg, B. R.; Josefowicz, S. Z.; Rice, C. M.
10.1101/2023.11.24.568354 — immunology — Posted on 2023-11-27
552 Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming
Shen, Y.-R.; Zaballa, S.; Bech, X.; Sancho-Balsells, A.; Diaz-Cifuentes, C.; Seyit-Bremer, G.; Ballasch, I.; Alcazar, N.; Alberch, J.; Abad, M.; Serrano, M.; Klein, R.; Giralt, A.; del Toro, D.
10.1101/2023.11.27.568858 — neuroscience — Posted on 2023-11-27
553 White matter lipidome alterations in the schizophrenia brain
Senko, D.; Osetrova, M.; Efimova, O.; Anikanov, N.; Tkachev, A.; Boyko, M.; Sharaev, M.; Morozova, A.; Zorkina, Y.; Kostyuk, G.; Stekolshchikova, E.; Khaitovich, P.
10.1101/2023.11.27.568452 — neuroscience — Posted on 2023-11-27
557 Rapid, DNA-induced interface swapping by DNA gyrase
Germe, T.; Bush, N. G.; Baskerville, V.; Saman, D.; Benesch, J. L.; Maxwell, A.
10.1101/2022.09.08.507137 — biochemistry — Posted on 2023-11-27
558 Biomolecular condensates in fungi are tuned to function at specific temperatures
Stormo, B. M.; McLaughlin, G.; Frederick, L.; Jalihal, A.; Cole, S.; Seim, I.; Dietrich, F.; Gladfelter, A. S.
10.1101/2023.11.27.568884 — cell biology — Posted on 2023-11-27
559 Phosphoproteomics identifies targets of Mos-MAPK regulating translation and spindle organization in oocyte meiosis
Avilov, I.; Horokhovskyi, Y.; Cai, M.; Orzechowski, A.; Welp, L.; Urlaub, H.; Liepe, J.; Lenart, P.
10.1101/2023.11.27.568807 — cell biology — Posted on 2023-11-27
561 Metal complexes and conjugation: Harnessing the power of cobalt complexes to curtail plasmid transfer
Alav, I.; Pordelkhaki, P.; de Resende, P. E.; Partington, H.; Gibbons, S.; Lord, R.; Buckner, M. M. C.
10.1101/2023.11.24.568573 — microbiology — Posted on 2023-11-27
563 Spatial analysis of Hofbauer cell transcriptome, distribution and morphology in placentas exposed to Plasmodium falciparum
Ataide, R.; Harding, R.; Dharmaratne, M.; Chen, Y.; Fielding, K.; Whitehead, L.; Rogers, K.; Anttila, C.; Ling, L.; Hickey, P.; Amann-Zalcenstein, D.; Moya, E.; Mhango, G.; Kamiza, S.; Randall, L.; Bennett, C.; Mzembe, G.; Mwangi, M. N.; Braat, S.; Phiri, K.; Pasricha, S.-R.
10.1101/2023.11.27.568491 — immunology — Posted on 2023-11-27
566 Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina
Krueppel, S.; Khani, M. H.; Schreyer, H. M.; Sridhar, S.; Ramakrishna, V.; Zapp, S. J.; Mietsch, M.; Karamanlis, D.; Gollisch, T.
10.1101/2023.11.27.568854 — neuroscience — Posted on 2023-11-27
568 Can changes in ploidy drive the evolution to allogamy in a selfing species complex?
Garcia-Munoz, A.; Ferron, C.; Vaca-Benito, C.; Martinez-Gomez, M. N.; Castro, S.; Castro, M.; Loureiro, J.; Munoz-Pajares, A. J.; Abdelaziz, M.
10.1101/2023.11.27.568831 — plant biology — Posted on 2023-11-27
574 Discovering Secondary Protein Structures via Local Euler Curvature
Moreira, R. A.; Braddell, R.; Santos, F. A. N.; Fulop, T.; Desroches, M.; Ubarretxena-Belandia, I.; Rodrigues, S.
10.1101/2023.11.27.568841 — biochemistry — Posted on 2023-11-27
575 Development of a Next Generation SNP Genotyping Array for Wheat
Burridge, A. J.; Winfield, M.; Przewieslik-Allen, A.; Edwards, K. J.; Siddique, I.; Barral-Arca, R.; Griffiths, S.; Cheng, S.; Huang, Z.; Feng, C.; Dreisigacker, S.; Bentley, A.; Brown-Guedira, G.; Barker, G.
10.1101/2023.11.27.568448 — genomics — Posted on 2023-11-27
581 RNA polymerase II transcription with partially assembled TFIID complexes
Hisler, V.; Bardot, P.; Detilleux, D.; Stierle, M.; Garcia Sanchez, E.; Richard, C.; Hadj Arab, L.; Ehrhard, C.; Morlet, B.; Hadziev, Y.; Jung, M.; Le Gras, S.; Negroni, L.; Mueller, F.; Tora, L.; Vincent, S. D.
10.1101/2023.11.27.567046 — molecular biology — Posted on 2023-11-27
583 Large-scale proteogenomics characterization of the Mycobacterium tuberculosis hidden microproteome
de Souza, E. V.; Dalberto, P. F.; Miranda, A. C.; Saghatelian, A.; Pinto, A. F. M.; Basso, L. A.; Machado, P.; Bizarro, C. V.
10.1101/2023.11.26.568715 — molecular biology — Posted on 2023-11-27
584 Mechanical loading rescues mechanoresponsiveness in a human osteoarthritis explant model despite Wnt activation
Castro-Vinuelas, R.; Viudes-Sarrion, N.; Rojo-Garcia, A. V.; Monteagudo, S.; Lories, R. J.; Jonkers, I.
10.1101/2023.11.27.568718 — molecular biology — Posted on 2023-11-27
585 Multicellular magnetotactic bacterial consortia are metabolically differentiated and not clonal
Schaible, G. A.; Jay, Z. J.; Cliff, J.; Schulz, F.; Gauvin, C.; Goudeau, D.; Malmstrom, R.; Ruff, S. E.; Edgcomb, V. P.; Hatzenpichler, R.
10.1101/2023.11.27.568837 — microbiology — Posted on 2023-11-27
586 Slow oscillation-spindle coupling predicts sequence-based language learning
Cross, Z. R.; Helfrich, R. F.; Corcoran, A. W.; Kohler, M. J.; Coussens, S.; Zou-Williams, L.; Schlesewsky, M.; Gaskell, M. G.; Knight, R. T.; Bornkessel-Schlesewsky, I.
10.1101/2020.02.13.948539 — neuroscience — Posted on 2023-11-27
588 Sex matters: the MouseX DW-ALLEN Atlas for mice diffusion-weighted MR imaging
Martinez-Tazo, P.; Santos, A.; Kotb Selim, M.; Espinos-Soler, E.; De Santis, S.
10.1101/2023.11.27.568800 — neuroscience — Posted on 2023-11-27
589 Sleep loss impairs myelin function by altering cholesterol metabolism in oligodendroglia
Simayi, R.; Ficiara, E.; Faniyan, O.; Cerdan Cerda, A.; Aboufares El Alaoui, A.; Fiorini, R.; Cutignano, A.; Piscitelli, F.; Andujar, P.; Santos, A.; Del Gallo, F.; de Vivo, L.; De Santis, S.; Bellesi, M.
10.1101/2023.11.27.568716 — neuroscience — Posted on 2023-11-27
590 Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species
Kjer, M.; Andersson, M.; He, Y.; Pacureanu, A.; Daducci, A.; Pizzolato, M.; Salditt, T.; Robisch, A.-L.; Eckermann, M.; Töpperwien, M.; Dahl, A. B.; Elkjaer, M. L.; Illes, Z.; Ptito, M.; Andersen Dahl, V.; Dyrby, T. B.
10.1101/2023.10.16.562488 — neuroscience — Posted on 2023-11-27
593 Defining the in vivo role of mTORC1 in thyrocytes by studying the TSC2 conditional knockout mouse model
Rossetti, C. L.; Lourenconi, B.; Pecanha, F. L. M.; Franco, A. T.; Nose, V.; Lew, J.; Carneiro, E.; Bernal-Mizrachi, E.; Werneck de Castro, J. P.
10.1101/2023.11.01.565171 — physiology — Posted on 2023-11-27
594 Force-mediated recruitment and reprogramming of healthy endothelial cells drive vascular lesion growth
Shapeti, A.; Barrasa Fano, J.; Abdel Fattah, A. R.; de Jong, J.; Sanz-Herrera, J. A.; Pezet, M.; ASSOU, S.; de Vet, E.; Elahi, S. A.; Ranga, A.; Faurobert, E.; Van Oosterwyck, H.
10.1101/2023.11.27.568780 — bioengineering — Posted on 2023-11-27
598 SOX2 and NR2F1 coordinate the gene expression program of the early postnatal visual thalamus
Serra, L.; Nordin, A.; Jonasson, M.; Marenco, C.; Gullo, F.; Ottolenghi, S.; Zambelli, F.; Studer, M.; Pavesi, G.; Cantu, C.; Nicolis, S. K.; Mercurio, S.
10.1101/2023.11.27.568801 — developmental biology — Posted on 2023-11-27
599 Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes
Dereli, I.; Telychko, V.; Papanikos, F.; Raveendran, K.; Xu, J.; Boekhout, M.; Stanzione, M.; Neuditschko, B.; Imjeti, N. S.; Selezneva, E.; Erbasi, H. T.; Demir, S.; Giannattasio, T.; Gentzel, M.; Stevense, M.; Barchi, M.; Bondarieva, A.; Schnittger, A.; Weir, J.; Herzog, F.; Keeney, S.; Toth, A.
10.1101/2023.11.27.568863 — cell biology — Posted on 2023-11-27
601 Thalamocortical interactions shape hierarchical neural variability during stimulus perception
Tauste Campo, A.; Zainos, A.; Vazquez, Y.; Adell Segarra, R.; Alvarez, M.; Deco, G.; Parra, S.; Romo, R.; Rossi Pool, R.
10.1101/2022.09.20.508691 — neuroscience — Posted on 2023-11-27
604 H2A.Z chaperones converge on histone H4 acetylation for melanoma cell proliferation
Jostes, S.; Vardabasso, C.; Dong, J.; Carcamo, S.; Singh, R.; Phelps, R.; Meadows, A.; Hasson, D.; Bernstein, E.
10.1101/2023.11.26.568747 — cancer biology — Posted on 2023-11-27
606 Climate change introduces threatened killer whale populations and conservation challenges to the Arctic
Garroway, C. J.; de Greef, E.; Lefort, K. J.; Thorstensen, M. J.; Foote, A.; Matthews, C. J.; Higdon, J. W.; Kucheravy, C. E.; Petersen, S. D.; Rosing-Asvid, A.; Ugarte, F.; Dietz, R.; Ferguson, S.
10.1101/2023.11.25.568606 — genomics — Posted on 2023-11-27
607 Multi-level 3D genome organization deteriorates during breast cancer progression
Rossini, R.; Oshaghi, M.; Nekrasov, M.; Bellanger, A.; Domaschenz, R.; Dijkwel, Y.; Abdelhalim, M.; Collas, P.; Tremethick, D.; Paulsen, J.
10.1101/2023.11.26.568711 — genomics — Posted on 2023-11-27
609 Epigenetic Small-Molecule Screen for Inhibition and Reversal of Acinar Ductal Metaplasia in Mouse Pancreatic Organoids
Atanasova, K. R.; Perkins, C. M.; Ratnayake, R.; Jiang, J.; Chen, Q.-Y.; Schmittgen, T. D.; Luesch, H.
10.1101/2023.11.27.567685 — cancer biology — Posted on 2023-11-27
611 Menopausal transition alters female skeletal muscle transcriptome
Juppi, H.-K.; Korhonen, T.-M.; Sievanen, T.; Kovanen, V.; Kujala, U. M.; Aukee, P.; Cronin, N.; Sipila, S.; Karvinen, S.; Laakkonen, E. K.
10.1101/2023.11.27.568782 — molecular biology — Posted on 2023-11-27
612 Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription.
Azouzi, C.; Schwank, K.; Queille, S.; Kwapisz, M.; Aguirrebengoa, M.; Henras, A.; Lebaron, S.; Tschochner, H.; Lesne, A.; Beckouet, F.; Gadal, O.; DEZ, c.
10.1101/2023.11.27.568781 — molecular biology — Posted on 2023-11-27
613 Estradiol Mediates Greater Germinal Center Responses to Influenza Vaccination in Female than Male Mice
Dhakal, S.; Park, H.-S.; Seddu, K.; Lee, J.; Creisher, P. S.; Davis, K. M.; Hernandez, I. R.; Maul, R. W.; Klein, S. L.
10.1101/2023.11.27.568847 — immunology — Posted on 2023-11-27
617 Genetically-clustered antifungal phytocytokines and receptor proteins function together to trigger plant immune signaling
Lintz, J.; Goto, Y.; Bender, K. W.; Bchini, R.; Dubrulle, G.; Cawston, E.; Zipfel, C.; Duplessis, S.; PETRE, B.
10.1101/2023.11.27.568785 — plant biology — Posted on 2023-11-27
618 Machine learning-guided optimization of p-coumaric acid production in yeast
Moreno-Paz, S.; van der Hoek, R.; Eliana, E.; Zwartjens, P.; Gosiewska, S.; Martins dos Santos, V. A. P.; Schmitz, J.; Suarez-Diez, M.
10.1101/2023.11.27.568789 — bioengineering — Posted on 2023-11-27
619 A population genomics approach to unlock the genetic potential of lablab (Lablab purpureus), an underutilized tropical forage crop
Teshome, A.; Habte, E.; Cheema, J.; Mekasha, A.; Lire, H.; Muktar, M. S.; Quiroz-Chavez, J.; domoney, C.; Jones, C.
10.1101/2023.11.27.568768 — genomics — Posted on 2023-11-27
620 Phylogeny-metabolism dual-directed single-cell genomics for dissecting and mining ecosystem function
Jing, X.; Gong, Y.; Diao, Z.; Ma, Y.; Meng, Y.; Chen, J.; Ren, Y.; Li, Y.; Sun, W.; Zhang, J.; Ji, Y.; Liang, Y.; Cong, Z.; Li, S.; Ma, B.; Cui, Z.; Ma, L.; Xu, J.
10.1101/2023.11.27.568714 — microbiology — Posted on 2023-11-27
623 Aging impairs muscle regeneration by desynchronizing matrix mechano-signaling and macrophage immunomodulation via fibro-adipogenic progenitors
Garcia-Carrizo, F.; Gohlke, S.; Lenihan-Geels, G.; Jank, A.-M.; Leer, M.; Soultoukis, G. A.; Oveisi, M.; Herpich, C.; Garrido, C. A.; Kotsaris, G.; Poehle-Kronawitter, S.; Tsamo-Tetou, A.; Graja, A.; Ost, M.; Villacorta, L.; Knecht, R. S.; Klaus, S.; Schuermann, A.; Stricker, S.; Schmidt-Bleek, K.; Cipitria, A.; Duda, G. N.; Benes, V.; Mueller-Werdan, U.; Norman, K.; Schulz, T. J.
10.1101/2023.11.27.568776 — physiology — Posted on 2023-11-27
627 Optimal investments in private land conservation depend more on landholder preferences than climate change
Williams, B.; Archibald, C. L.; Brazill-Boast, J.; Drielsma, M.; Thapa, R.; Love, J.; Cho, F.; Lunney, D.; Fitzsimons, J.; Iftekhar, S.; Villarreal-Rosas, J.; Bekessy, S.; Heterington, S.; McAlpine, C.; Beaumont, L. J.; Thonell, J.; Rhodes, J.
10.1101/2023.11.26.568746 — ecology — Posted on 2023-11-27
629 Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.
Gibson, A.; Ram, R.; Gangula, R.; Li, Y.; Mukherjee, E.; Palubinsky, A. M.; Campbell, C. N.; Thorne, M.; Konvinse, K. C.; Choshi, P.; Deshpande, P.; Pedretti, S.; O'Neil, R. T.; Wanjalla, C. N.; Kalams, S. A.; Gaudieri, S.; Lehloenya, R. J.; Bailin, S. S.; Chopra, A.; Trubiano, J. A.; Peter, J. G.; Mallal, S. A.; Phillips, E. J.
10.1101/2023.11.26.568771 — immunology — Posted on 2023-11-27
631 The Myc-Like Mlx Network Impacts Aging and Metabolism
Wang, H.; Stevens, T.; Lu, J.; Roberts, A.; Land, C.; muzumdar, r.; gong, z.; Vockley, J.; Prochownik, E. V.
10.1101/2023.11.26.568749 — cancer biology — Posted on 2023-11-27
640 Giotto Suite: a multi-scale and technology-agnostic spatial multi-omics analysis ecosystem
Chen, J. G.; Chavez-Fuentes, J. C.; O'Brien, M.; Xu, J.; Ruiz, E.; Wang, W.; Amin, I.; Sarfraz, I.; Guckhool, P.; Sistig, A.; Yuan, G.-C.; Dries, R.
10.1101/2023.11.26.568752 — bioinformatics — Posted on 2023-11-27
641 Mapping the gene space at single-cell resolution with gene signal pattern analysis
Venkat, A.; Leone, S.; Youlten, S. E.; Fagerberg, E.; Attanasio, J.; Joshi, N. S.; Perlmutter, M.; Krishnaswamy, S.
10.1101/2023.11.26.568492 — bioinformatics — Posted on 2023-11-27
646 Proliferation history and transcription factor levels drive direct conversion
Wang, N. B.; Lende-Dorn, B. A.; Adewumi, H. O.; Beitz, A. M.; Han, P.; O'Shea, T. M.; Galloway, K. E.
10.1101/2023.11.26.568736 — cell biology — Posted on 2023-11-27
650 Isolating neural signatures of conscious speech perception with a no-report sine-wave speechparadigm
Zhu, Y.; Li, C.; Hendry, C.; Glass, J.; Canseco-Gonzalez, E.; Pitts, M. A.; Dykstra, A. R.
10.1101/2023.11.26.568128 — neuroscience — Posted on 2023-11-27
651 Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ
Hönes, G. S.; Geist, D.; Wenzek, C.; Pfluger, P. T.; Müller, T. D.; Amarie, O. V.; Becker, L.; Dragano, N.; Garrett, L.; Hölter, S. M.; Rathkolb, B.; Rozman, J.; Spielmann, N.; Treise, I.; Wolf, E.; Wurst, W.; Fuchs, H.; Gailus-Durner, V.; de Angelis, M. H.; Führer, D.; Moeller, L. C.
10.1101/2023.11.26.568063 — physiology — Posted on 2023-11-27
652 HIHISIV: a database of gene expression in HIV and SIV host immune response
Costa, R. L.; Gadelha, L. M. R.; D'arc, M. M. R.; Ribeiro-Alves, M.; Robertson, D. L.; Schwartz, J.-M. L.; Soares, M. A.; Porto, F.
10.1101/2023.11.25.568664 — bioinformatics — Posted on 2023-11-27
653 Genomic selection for herbage yield in forage oats (Avena sp.)
Rocha, D. J. A.; Flaresso, J. A.; Neto, J. S.; Cordova, U. A.
10.1101/2023.11.24.568597 — genetics — Posted on 2023-11-27
654 Connecting single neuron transcriptomes to the projectome in mouse visual cortex
Sorensen, S. A.; Gouwens, N. W.; Wang, Y.; Mallory, M.; Budzillo, A.; Dalley, R.; Lee, B. R.; Gliko, O.; Kuo, H.; Kuang, X.; Mann, R.; Ahmadinia, L.; Alfiler, L.; Baftizadeh, F.; Baker, K. S.; Bannick, S.; Bertagnolli, D.; Bickley, K.; Bohn, P.; Bomben, J.; Boyer, G.; Brouner, K.; Cahoon, A.; Chen, N.; Chen, C.; Chen, K.; Chvilicek, M.; Collman, F.; Daigle, T. L.; Dawes, T.; de Frates, R.; Dee, N.; DePartee, M.; Egdorf, T.; El-Hifnawi, L.; Esposito, L.; Farrell, C.; Gala, R.; Gamlin, C.; Gary, A.; Goldy, J.; Gu, H.; Hadley, K.; Hawrylycz, M.; Henry, A.; Hill, D.; Hirokawa, K. E.; Huang, Z.; Jo
10.1101/2023.11.25.568393 — neuroscience — Posted on 2023-11-27
655 Crosstalk between Gut Sensory Ghrelin Signaling and Adipose Tissue Sympathetic Outflow Regulates Metabolic Homeostasis
Thomas, M. A.; Cui, X.; Artinian, L. R.; Cao, Q.; Jing, J.; Silva, F. C.; Wang, S.; Zigman, J. M.; Sun, Y.; Shi, H.; Xue, B.
10.1101/2023.11.25.568689 — neuroscience — Posted on 2023-11-27
656 Locally low-rank denoising in transform domains
Moeller, S.; Buko, E. O.; Pathan, S. P.; Dowdle, L.; Ugurbil, K.; Johnson, C.; Akcakaya, M.
10.1101/2023.11.21.568193 — scientific communication and education — Posted on 2023-11-27
661 Two functionally distinct HEATR5 protein complexes are defined by fast-evolving co-factors in yeast
Marmorale, L. J.; Jin, H.; Reidy, T. G.; Palomino-Alonso, B.; Zysnarski, C.; Jordan-Javed, F.; Lahiri, S.; Duncan, M. C.
10.1101/2023.08.24.554671 — cell biology — Posted on 2023-11-27
663 Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses
Kretsch, R. C.; Xu, L.; Zheludev, I. N.; Zhou, X.; Huang, R.; Nye, G.; Li, S.; Zhang, K.; Chiu, W.; Das, R.
10.1101/2023.11.22.567964 — biophysics — Posted on 2023-11-27
664 Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity.
Bläsius, K.; Ludwig, L.; Knapp, S.; Flasshove, C.; Sonnabend, F.; Keller, D.; Tacken, N.; Gao, X.; Kahveci, S.; Grannemann, C.; Babendreyer, A.; Adrain, C.; Huth, S.; Baron, J.; Ludwig, A.; Düsterhöft, S.
10.1101/2023.08.31.555720 — molecular biology — Posted on 2023-11-27
665 Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia
Monzel, M.; Leelaarporn, P.; Lutz, T.; Schultz, J.; Brunheim, S.; Reuter, M.; McCormick, C.
10.1101/2023.08.11.552915 — neuroscience — Posted on 2023-11-27
668 CXCR4 blockade alleviates pulmonary and cardiac outcomes in young COPD
Dupin, I.; Henrot, P.; Maurat, E.; Abohalaka, R.; Chaigne, S.; El Hamrani, D.; Eyraud, E.; Prevel, R.; Esteves, P.; Campagnac, M.; Dubreuil, M.; Cardouat, G.; Bouchet, C.; Ousova, O.; Dupuy, J.-W.; Trian, T.; Thumerel, M.; Begueret, H.; Girodet, P.-O.; Marthan, R.; Zysman, M.; Michel, V.; Berger, P.
10.1101/2023.03.10.529743 — pathology — Posted on 2023-11-27
669 Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase.
Boulet, M.; Gilbert, G.; Renaud, Y.; Schmidt-Dengler, M.; Plantie, E.; Bertrand, R.; Nan, X.; Jurkowski, T.; Helm, M.; Vandel, L.; Waltzer, L.
10.1101/2023.09.15.557947 — molecular biology — Posted on 2023-11-27
671 The Dynamics of Context-Dependent Space Representations in Auditory Cortex
Myoga, M. H.; Amaro, D.; Kello, V.; Gumbert, M.; Leibold, C.; Pecka, M.; Grothe, B.
10.1101/2023.11.25.568638 — neuroscience — Posted on 2023-11-27
674 Dynamic floral scent profile of Epiphyllum oxypetalum and the cytosolic biosynthesis of trans-Geraniol through mevalonate pathway
Zhang, Y.; Zhang, Y.; Tian, Q.; Wei, L.; Tang, W.; Zhu, T.; Zhou, Z.; Wang, J.; Xiao, H.; Liu, Z.; Li, T.; Sun, Q.
10.1101/2023.11.26.568706 — plant biology — Posted on 2023-11-27
676 Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations
Zhou, X.; Wang, Z. J.; Camps, J.; Tomek, J.; Santiago, A.; Quintanas, A.; Vazquez, M.; Vaseghi, M.; Rodriguez, B.
10.1101/2022.02.15.480392 — bioengineering — Posted on 2023-11-27
677 Genomic-guided conservation actions to restore the most endangered conifer in the Mediterranean Basin
del Valle, J. C.; Arista, M.; Benitez-Benitez, C.; Jimenez-Lopez, J.; Ortiz, P. L.; Terrab, A.; Balao, F.
10.1101/2023.11.24.568549 — genomics — Posted on 2023-11-27
678 Distinct Roles of Kif6 and Kif9 in Mammalian Ciliary Trafficking and Motility
Fang, C.; Pan, X.; Li, D.; Chen, Y.; Li, L.; Gao, Q.; Li, D.; Zhu, X.; Yan, X.
10.1101/2023.11.09.564704 — cell biology — Posted on 2023-11-27
679 Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification
Fruchard, L.; Babosan, A.; Carvalho, A.; Lang, M.; Li, B.; Duchateau, M.; Giai Gianetto, Q.; Matondo, M.; Bonhomme, F.; Hatin, I.; Arbes, H.; Fabret, C.; Sanchez, G.; MArchand, V.; Motorine, Y.; NAMY, O.; de Crecy-Lagard, V.; Mazel, D.; Baharoglu, Z.
10.1101/2022.09.26.509455 — microbiology — Posted on 2023-11-27
680 Nifuroxazide Suppresses PD-L1 Expression and Enhances the Efficacy of Radiotherapy in Hepatocellular Carcinoma
Zhao, T.; Wei, P.; Zhang, C.; Zhou, S.; Liang, L.; Guo, S.; Yin, Z.; Cheng, S.; Gan, Z.; Xia, Y.; Zhang, Y.; Guo, S.; Zhong, J.; Yang, Z.; Tu, F.; Wang, Q.; Bai, J.; Ren, F.; Feng, Z.; Jia, H.
10.1101/2023.09.03.556121 — immunology — Posted on 2023-11-27
681 Engineering Modular and Tunable Single Molecule Sensors by Decoupling Sensing from Signal Output
Grabenhorst, L.; Pfeiffer, M.; Schinkel, T.; Kümmerlin, M.; Maglic, J. B.; Brüggenthies, G. A.; Selbach, F.; Murr, A. T.; Tinnefeld, P.; Glembockyte, V.
10.1101/2023.11.06.565795 — biophysics — Posted on 2023-11-27
682 A genome-wide association study of neonatal metabolites
He, Q.; Liu, H.; Lu, L.; Zhang, Q.; Wang, Q.; Wang, B.; Wu, X.; Guan, L.; Mao, J.; Xue, Y.; Zhang, C.; He, Y.; Peng, X.; Peng, H.; Zhao, K.; Li, H.; Jin, X.; Zhao, L.; Zhang, J.; Wang, T.
10.1101/2023.11.25.568687 — genetics — Posted on 2023-11-27
685 Anisotropic interaction and motion states of locusts in a hopper band
Weinburd, J.; Landsberg, J.; Kravtsova, A.; Lam, S.; Sharma, T.; Simpson, S. J.; Sword, G. A.; Buhl, J.
10.1101/2021.10.29.466390 — animal behavior and cognition — Posted on 2023-11-27
687 Fecal microbiota transplantation from individual with bipolar disorder and healthy control elicits distinct behaviors and metabolite profiles in mice
Bukowski-Thall, G.; Fellendorf, F.; Gorkiewicz, S.; Ip, K. C. K.; Schmidt, L.; Durdevic, M.; Habisch, H.; Mörkl, S.; Wagner-Skacel, J.; Bengesser, S.; Lenger, M.; Dalkner, N.; Gorkiewicz, G.; Högenauer, C.; Madl, T.; Moissl-Eichinger, C.; Farzi, A.; Reininghaus, E.
10.1101/2023.11.16.566698 — microbiology — Posted on 2023-11-26
691 Test-retest reliability of spectral parameterization by 1/f characterization using SpecParam
McKeown, D. J.; Finley, A.; Kelley, N.; Cavanagh, J.; Keage, H.; Baumann, O.; Schinazi, V.; Moustafa, A.; Angus, D.
10.1101/2023.09.20.558566 — neuroscience — Posted on 2023-11-26
694 Evolution is All You Need in Promoter Design and Optimization
Ren, R.; Yu, H.; Teng, J.; Mao, S.; Bian, Z.; Tao, Y.; Yau, S. S.-T.
10.1101/2023.11.18.567645 — synthetic biology — Posted on 2023-11-26
696 Repeat mediated excision of gene drive elements for restoring wild-type populations
Chennuri, P. R.; Zapletal, J.; Monfardini, R. D.; Ndeffo-Mbah, M. L.; Adelman, Z.; Myles, K. M. M.
10.1101/2023.11.23.568397 — genetics — Posted on 2023-11-26
697 Cell-cell adhesion drives patterning in stratified epithelia
Mai, Y.; Kobayashi, Y.; Kitahata, H.; Seo, T.; Nohara, T.; Itamoto, S.; Mai, S.; Kumamoto, J.; Nagayama, M.; Nishie, W.; Ujiie, H.; Natsuga, K.
10.1101/2023.11.24.567740 — cell biology — Posted on 2023-11-26
699 Fertilizer and cultivar affect the barley rhizobiome, while domestication age only affects growth at low nutrient levels
Kindtler, N. L.; Sheikh, S.; Richardy, J.; Krogh, E.; Maccario, L.; Vestergard, M.; da Fonseca, R. R.; Ekelund, F.; Laursen, K. H.
10.1101/2023.11.24.568554 — plant biology — Posted on 2023-11-26
700 Microsatellite Density Landscapes Illustrate Short Tandem Repeats Aggregation in The Complete Reference Human Genome
Xia, Y.; Li, D.; Chen, T.; Pan, S.; Huang, H.; Zhang, W.; Liang, Y.; Fu, Y.; Peng, Z.; Zhang, H.; Zhang, L.; Peng, S.; Shi, R.; He, X.; Zhou, S.; Jiao, W.; Zhao, X.; Wu, X.; Zhou, L.; Zhou, J.; Ouyang, Q.; Tian, Y.; Jiang, X.; Zhou, Y.; Tang, S.; Shen, J.; Ohshima, K.; Tan, Z.
10.1101/2022.04.16.487617 — bioinformatics — Posted on 2023-11-26
701 Large-scale proteogenomics characterization of the Mycobacterium tuberculosis hidden microproteome
de Souza, E. V.; Dalberto, P. F.; Miranda, A. C.; Saghatelian, A.; Pinto, A. F. M.; Basso, L. A.; Machado, P.; Bizarro, C. V.
10.1101/2023.11.26.568715 — molecular biology — Posted on 2023-11-26
705 An interdependent Metabolic and Genetic Network shows emergent properties in vitro
Giaveri, S.; Bohra, N.; Diehl, C.; Ballinger, M.; Paczia, N.; Glatter, T.; Erb, T. J.
10.1101/2023.11.26.568713 — synthetic biology — Posted on 2023-11-26
707 Characterization of tomato canal-1 mutant using a multi-omics approach
Ahchige, M. W.; Fisher, J.; Sokolowska, E.; Lyall, R.; Illing, N.; Skirycz, A.; Zamir, D.; Alseekh, S.; Fernie, A. R.
10.1101/2023.11.26.567847 — plant biology — Posted on 2023-11-26
709 Phosphatase-independent activity of smooth-muscle calcineurin orchestrates a gene expression program leading to hypertension
Yunes-Leites, P. S.; Sun, Y.; Martinez-Martinez, S.; Alfayate, A.; Toral, M.; Colmenar, A.; Torralbo, A. I.; Lopez-Maderuelo, D.; Mateos-Garcia, S.; Cornfield, D. N.; Vazquez, J.; Redondo, J. M.; Campanero, M. R.
10.1101/2023.11.26.568733 — pathology — Posted on 2023-11-26
710 H2A.Z chaperones converge on histone H4 acetylation for melanoma cell proliferation
Jostes, S.; Vardabasso, C.; Dong, J.; Carcamo, S.; Singh, R.; Phelps, R.; Meadows, A.; Hasson, D.; Bernstein, E.
10.1101/2023.11.26.568747 — cancer biology — Posted on 2023-11-26
713 De novo design and optimization of aptamers with AptaDiff
Wang, Z.; Liu, Z.; Zhang, W.; Li, Y.; Feng, Y.; Lv, S.; Diao, H.; Luo, Z.; Yan, P.; He, M.; Li, X.
10.1101/2023.11.25.568693 — bioinformatics — Posted on 2023-11-26
715 Analysis of Wilms' tumor protein 1 specific TCR repertoire in AML patients uncovers higher diversity in patients in remission than in relapsed
Gielis, S.; Flumens, D.; van der Heijden, S.; Versteven, M.; De Reu, H.; Bartholomeus, E.; Schippers, J.; Campillo-Davo, D.; Berneman, Z.; Anguille, S.; Smits, E.; Ogunjimi, B.; Lion, E.; Laukens, K.; Meysman, P.
10.1101/2023.11.26.568717 — bioinformatics — Posted on 2023-11-26
719 Individuality across environmental context in Drosophila melanogaster
Mathejczyk, T.; Knief, C.; Haidar, M. A.; Freitag, F.; McClary, T.; Wernet, M. F.; Linneweber, G. A.
10.1101/2023.11.26.568741 — animal behavior and cognition — Posted on 2023-11-26
722 Origin Of Evolutionary Bifurcation In An Enzyme
Miton, C. M.; Campbell, E. C.; Kaczmarski, J. A.; Feixas, F.; Romero-Rivera, A.; Sandhu, M.; Anderson, D. W.; Shatani, N.; Osuna, S.; Jackson, C. J.; Tokuriki, N.
10.1101/2023.11.25.568631 — evolutionary biology — Posted on 2023-11-26
727 Mechanism of high energy efficiency of carbon fixation by sulfur-oxidizing symbionts revealed by single-cell analyses and metabolic modeling
Kleiner, M.; Polerecky, L.; Lott, C.; Bergin, C.; Haeusler, S.; Liebeke, M.; Wentrup, C.; Musat, N.; Kuypers, M. M. M.; Dubilier, N.
10.1101/2023.11.25.568684 — microbiology — Posted on 2023-11-26
735 Ageing impairs the regenerative capacity of regulatory T cells in central nervous system remyelination
de la Fuente, A. G.; Dittmer, M.; Heesbeen, E.; de la Vega-Gallardo, N.; White, J. A.; Young, A.; McColgan, T.; Dashwood, A.; Mayne, K.; Cabeza-Fernandez, S.; Falconer, J.; Rodriguez-Baena, F. J.; McMurran, C. E.; Innayatulah, M.; Rawji, K. S.; Franklin, R. J.; Dooley, J.; Liston, A.; Ingram, R. J.; Tiwari, V. K.; Penalva, R.; Dombrowski, Y.; Fitzgerald, D. C.
10.1101/2023.01.25.525562 — neuroscience — Posted on 2023-11-26
739 Chrysin directing an enhanced solubility through the formation of a supramolecular cyclodextrin-calixarene drug delivery system: a potential strategy in antifibrotic diabetes therapeutics
Hermenean, A.; Dossi, E.; Hamilton, A.; Trotta, M. C.; Russo, M.; Lepre, C. C.; Sajtos, C.; Rusznyak, A.; Varadi, J.; Bacskay, I.; DAmico, M.; Fenyvesi, F.
10.1101/2023.10.03.560552 — pharmacology and toxicology — Posted on 2023-11-26
745 Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
Chen, X.; Li, Y.; Xu, J.; Cui, Y.; Wu, Q.; Yin, H.; Li, Y.; Gao, C.; Jiang, L.; Wang, H.; Wen, Z.; Yao, Z.; Wu, Z.
10.1101/2022.10.22.513336 — developmental biology — Posted on 2023-11-26
746 Autotrophic growth of E. coli is achieved by a small number of genetic changes
Ben Nissan, R.; Milshtein, E.; Pahl, V.; de Pins, B.; Jona, G.; Levi, D.; Yung, H.; Nir, N.; Ezra, D.; Gleizer, S.; Link, H.; Noor, E.; Milo, R.
10.1101/2023.06.03.543535 — synthetic biology — Posted on 2023-11-26
747 Multiplexed effector screening for recognition by endogenous resistance genes using positive defense reporters in wheat protoplasts
Wilson, S.; Dagvadorj, B.; Tam, R.; Murphy, L.; Schulz-Kroenert, S.; Heng, N.; Crean, E.; Greenwood, J.; Rathjen, J.; Schwessinger, B.
10.1101/2023.04.30.538885 — plant biology — Posted on 2023-11-26
749 Adaptive functions correlate with evoked neurotransmitter release in SYT1-associated neurodevelopmental disorder
Park, P. Y.; Bleakley, L. E.; Saraya, N.; Al-Jawahiri, R.; Eck, J.; Aloi, M. A.; Melland, H.; Baker, K.; Gordon, S. L.
10.1101/2023.11.25.568507 — neuroscience — Posted on 2023-11-26
752 Identification of 1600 replication origins in S. cerevisiae
Foss, E. J.; Lichauco, C.; Gatbonton-Schwager, T.; Gonske, S. J.; Lofts, B.; Lao, U.; Bedalov, A.
10.1101/2023.04.11.536402 — genetics — Posted on 2023-11-25
756 Whole-genome sequencing of major malaria vectors reveals the evolution of new insecticide resistance variants in a longitudinal study in Burkina Faso
Kientega, M.; Clarkson, C. S.; Traore, N.; Hui, T.-Y. J.; O'Loughlin, S. M.; Millogo, A.-A.; Yao, F. A.; Epopa, P. S.; Belem, A. M. G.; Jon, B. H.; Miles, A.; Burt, A.; Diabate, A.
10.1101/2023.11.20.567800 — evolutionary biology — Posted on 2023-11-25
760 A modular model integrating metabolism, growth, and cell cycle predicts that fermentation is required to modulate cell size in yeast populations
Vanoni, M.; Palumbo, P.; Papa, F.; Busti, S.; Gotti, L.; Wortel, M. T.; Teusink, B.; Orlandi, I.; Pessina, A.; Airoldi, C.; Brambilla, L.; Vai, M.; Alberghina, L.
10.1101/2023.11.25.568635 — systems biology — Posted on 2023-11-25
761 AptaBERT: Predicting aptamer binding interactions
Morsch, F.; Umasankar, I. L.; Sanz Moreta, L.; Latawa, P.; Lange, D. B.; Wengel, J.; Konjen, H.; Code, C.
10.1101/2023.11.24.568626 — bioinformatics — Posted on 2023-11-25
763 A Multifaceted Framework To Assess tradeoffs in Performances Of Alternative JSDM
Violet, C.; Boye, A.; Chevalier, M.; Gauthier, O.; Grall, J.; Marzloff, M. P.
10.1101/2022.12.19.519605 — ecology — Posted on 2023-11-25
767 The Dynamics of Context-Dependent Space Representations in AC
Myoga, M. H.; Amaro, D.; Kello, V.; Gumbert, M.; Leibold, C.; Pecka, M.; Grothe, B.
10.1101/2023.11.25.568638 — neuroscience — Posted on 2023-11-25
769 epDevAtlas: Mapping GABAergic cells and microglia in postnatal mouse brains
Liwang, J. K.; Kronman, F. A.; Minteer, J. A.; Wu, Y.-t.; Vanselow, D. J.; Ben Simon, Y.; Taormina, M.; Parmaksiz, D.; Way, S. W.; Zeng, H.; Tasic, B.; Ng, L.; Kim, Y.
10.1101/2023.11.24.568585 — neuroscience — Posted on 2023-11-25
770 Bait, not reward: CO2-enriched Nepenthes pitchers secrete toxic nectar
Lathika, C. C.; Sujatha, G. B.; Thomas, G.; Johnson, A. J.; Viswanathan, G.; Varghese, T. S.; Mohamed, S.; Shereefa, L. A.; Baby, S.
10.1101/2023.11.25.568661 — plant biology — Posted on 2023-11-25
771 Next-Gen Profiling of Tumor-resident Stem Cells using Machine learning
Chowdhury, D.; Neekhra, B.; Priyadarshi, S.; Mukherjee, S.; Maity, D.; Gupta, D.; Haldar, S.
10.1101/2023.11.24.568600 — cancer biology — Posted on 2023-11-25
772 Developing folate-conjugated miR-34a therapeutic for prostate cancer treatment: Challenges and promises
Li, W.; Wang, Y.; Liu, X.; Wu, S.; Wang, M.; Tracz, A.; Abdelaal, A. M.; Sudarshan, K.; Puzanov, I.; Chatta, G.; Kasinski, A. L.; Tang, D. G.
10.1101/2023.11.25.568612 — cancer biology — Posted on 2023-11-25
776 Tuning of granulopoietic signaling by de novo designed agonists
Ullrich, T.; Pollmann, C.; Ritter, M.; Haaf, J.; Aghaallaei, N.; Tesakov, I.; El-Riz, M.; Maksymenko, K.; Hatskovska, V.; Kandabarau, S.; Klimiankou, M.; Lengerke, C.; Welte, K.; Hernandez Alvarez, B.; Müller, P.; Lupas, A. N.; Piehler, J.; Skokowa, J.; ElGamacy, M.
10.1101/2023.11.25.568662 — bioengineering — Posted on 2023-11-25
783 A fast and inexpensive plate-based NGS library preparation method for insect genomics
Cobb, L.; de Muinck, E. J.; Kollias, S.; Skage, M.; Gilfillan, G.; Qiao, S.-W.; Sydenham, M.; Star, B.
10.1101/2023.11.24.568434 — genomics — Posted on 2023-11-25
784 Genomic-guided conservation actions to restore the most endangered conifer in the Mediterranean Basin
del Valle, J. C.; Arista, M.; Benitez-Benitez, C.; Jimenez-Lopez, J.; Ortiz, P. L.; Terrab, A.; Balao, F.
10.1101/2023.11.24.568549 — genomics — Posted on 2023-11-25
785 Well-Paired-Seq2: High-Throughput and High-Sensitivity Strategy for Characterizing Low RNA-Content Cell/Nucleus Transcriptomes
Yang, C.; Yin, K.; Zhao, M.; Xu, Y.; Zheng, Z.; Huang, S.; Liang, D.; Dong, H.; Guo, Y.; Lin, L.; song, j.; Zhang, H.; Zheng, J.; Zhu, Z.
10.1101/2023.11.24.568621 — genetics — Posted on 2023-11-25
787 Efficient scar-free knock-ins of several kilobases by engineered CRISPR/Cas endonucleases
Schreiber, T.; Prange, A.; Schaefer, P.; Iwen, T.; Gruetzner, R.; Marillonnet, S.; Tissier, A. F.
10.1101/2023.11.24.568561 — molecular biology — Posted on 2023-11-25
789 Cross-Comparison of Gut Metagenomic Profiling Strategies
Gulyas, G.; Kakuk, B.; Dormo, A.; Jaray, T.; Prazsak, I.; Csabai, Z.; Henkrich, M. M.; Boldogkoi, Z.; Tombacz, D.
10.1101/2023.11.25.568646 — microbiology — Posted on 2023-11-25
790 Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation.
Cook, P. C.; Brown, S. L.; Houlder, E. L.; Baker, S.; Svedberg, F. R.; Howell, G.; Bertuzzi, M.; Boon, L.; Konkel, J. E.; Allen, J. E.; MacDonald, A. S.
10.1101/2023.11.24.568263 — immunology — Posted on 2023-11-25
792 NF1 deficiency drives metabolic reprogramming in ER+ breast cancer
House, R. J.; Tovar, E. A.; Essenburg, C. J.; Dischinger, P. S.; Ellis, A. E.; Beddows, I.; Sheldon, R. D.; Lien, E. C.; Graveel, C. R.; Steensma, M. R.
10.1101/2023.11.24.568339 — cancer biology — Posted on 2023-11-25
793 Development of selective pyridopyrimidin-7(8H)-one-based Mammalian STE20-like (MST3/4) kinase inhibitors
Rak, M.; Menge, A.; Tesch, R.; Berger, L. M.; Balourdas, D.-I.; Shevchenko, E.; Kraemer, A.; Elson, L.; Berger, B.-T.; Abdi, I.; Wahl, L. M.; Poso, A.; Kaiser, A.; Hanke, T.; Kronenberger, T.; Joerger, A. C.; Mueller, S.; Knapp, S.
10.1101/2023.11.24.568596 — biochemistry — Posted on 2023-11-25
795 Evidence for a role of 5-HT-glutamate co-releasing neurons in acute stress mechanisms
Gullino, L. S.; Fuller, C.; Dunn, P.; Collins, H. M.; El Mestikawy, S.; Sharp, T.
10.1101/2023.11.25.568634 — neuroscience — Posted on 2023-11-25
796 Development and validation of a pharmacogenomics reporting workflow based on the Illumina Global Screening Array chip
Gan, P.; Hajis, M. I. b.; Yumna, M.; Haruman, J.; Matoha, H. K.; Wahyudi, D. T.; Silalahi, S.; Oktariani, D. R.; Dela, F.; Annisa, T.; Pitaloka, T. D. A.; Adhiwijaya, P. K.; Pauzi, R. Y.; Hertanto, R.; Kumaheri, M. A.; Sani, L.; Irwanto, A.; Pradipta, A.; Chomchopbun, K.; Gonzalez-Porta, M.
10.1101/2023.11.24.568510 — genetics — Posted on 2023-11-25
797 Bdellovibrio's Prey-Independent Growth is Fuelled by Amino Acids as a Carbon Source
Herencias, C.; Rivero-Buceta, M. V.; Salgado, S.; Baquero, F.; del Campo, R.; Nogales, J.; Prieto, M. A.
10.1101/2023.11.24.568592 — microbiology — Posted on 2023-11-25
798 Running to remember: The effects of exercise on perineuronal nets, microglia, and hippocampal angiogenesis in female and male mice
Maheu, M. G.; James, N.; Clark, Z.; Yang, A.; Patel, R.; Beaudette, S. M.; MacPherson, R. E. K.; Duarte-Guterman, P.
10.1101/2023.11.24.568577 — neuroscience — Posted on 2023-11-25
799 Unraveling Coinfection Dynamics into 100 Whole Genome of Diarrheal Pathogens: A Genome-to-Systems Biology Approach with Plesiomonas shigelloides
Hossain, M. U.; Rahman, A. B. Z. N.; Hossain, M. S.; Dey, S.; Chowdhury, Z. M.; Bhattacharjee, A.; Ahammad, I.; Ahmed, M. I.; Sultana, K. F.; Hashem, A.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.11.24.568624 — systems biology — Posted on 2023-11-25
805 Genomic reconstruction of the successful establishment of a feralized bovine population on the subantarctic island of Amsterdam
Gautier, M.; Micol, T.; Camus, L.; Moazami-Goudarzi, K.; Naves, M.; Gueret, E.; Engelen, S.; Colas, F.; Flori, L.; Druet, T.
10.1101/2023.11.24.568563 — evolutionary biology — Posted on 2023-11-25
808 Serotonergic mediation of orienting and defensive responses in zebrafish
do Nascimento, B. G.; Rodrigues, J. R.; Silva, M. C. R.; Dutra Costa, B. P.; Silva, M. L.; Pyterson, M. P.; Silva, H. T. L.; Bruce de Souza, L. V. X.; de Siqueira-Silva, D. H.; Maximino, C.
10.1101/2023.11.24.568601 — neuroscience — Posted on 2023-11-25
809 Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice
Geist, D.; Hönes, G. S.; Grund, S. C.; Pape, J.; Siemes, D.; Spangenberg, P.; Tolstik, E.; Dörr, S.; Spielmann, N.; Fuchs, H.; Gailus-Durner, V.; Hrabe de Angelis, M.; Mittag, J.; Engel, D. R.; Führer, D.; Lorenz, K.; Moeller, L. C.
10.1101/2023.11.24.568041 — physiology — Posted on 2023-11-25
811 EmbedGEM: A framework to evaluate the utility of embeddings for genetic discovery
Mukherjee, S.; McCaw, Z. R.; Pei, J.; Merkoulovitch, A.; Tandon, R.; Soare, T. W.; Amar, D.; Somineni, H.; Klein, C.; Satapati, S.; Lloyd, D.; Probert, C.; Insitro Research Team, ; Koller, D.; O'Dushlaine, C.; Karaletsos, T.
10.1101/2023.11.24.568344 — bioinformatics — Posted on 2023-11-25
812 CryoET reveals actin filaments within platelet microtubules
Tsuji, C.; Bradshaw, M.; Allen, M.; Jackson, M. L.; Mantell, J.; Borucu, U.; Poole, A. W.; Verkade, P.; Hers, I.; Paul, D. M.; Dodding, M.
10.1101/2023.11.24.568450 — cell biology — Posted on 2023-11-25
814 High-fidelity, high-resolution light-field reconstruction with physics-informed neural representation learning
Yi, C.; Ma, Y.; Yuan, X.; Zhu, L.; Sun, J.; Gao, S.; Zhang, M.; Zhang, Y.; Wang, Z.; Tzung, H.; Li, D.; Liu, b.; Fei, P.
10.1101/2023.11.25.568636 — cell biology — Posted on 2023-11-25
815 TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity
Tollot-Wegner, M.; Jessen, M. A.; Kim, K.; Sanz-Moreno, A.; Spielmann, N.; Gailus-Durner, V.; Fuchs, H.; Hrabe de Angelis, M.; von Eyss, B.
10.1101/2023.11.24.568520 — cell biology — Posted on 2023-11-25
816 Propofol anesthesia destabilizes neural dynamics across cortex
Eisen, A. J.; Kozachkov, L.; Bastos, A. M.; Donoghue, J. A.; Mahnke, M. K.; Brincat, S. L.; Chandra, S.; Brown, E. N.; Fiete, I.; Miller, E. K.
10.1101/2023.11.24.568595 — neuroscience — Posted on 2023-11-25
818 Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure
Faysal, K. M. R.; Walsh, J. C.; Renner, N.; Marquez, C. L.; Shah, V.; Tuckwell, A. J.; Christie, M. P.; Parker, M. W.; Turville, S. G.; James, L.; Towers, G. J.; Jacques, D. A.; Boecking, T.
10.1101/2022.09.21.508807 — biophysics — Posted on 2023-11-25
821 Genome of the endangered eastern quoll (Dasyurus viverrinus) reveals signatures of historical decline and pelage color evolution.
Hartley, G. A.; Frankenberg, S. R.; Robinson, N. M.; MacDonald, A. J.; Hamede, R. K.; Burridge, C. P.; Jones, M. E.; Faulkner, T.; Shute, H.; Rose, K.; Brewster, R.; O'Neill, R. J.; Renfree, M. B.; Pask, A. J.; Feigin, C. Y.
10.1101/2023.09.06.556354 — genomics — Posted on 2023-11-25
822 Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter
Hariharan, P.; Shi, Y.; Katsube, S.; Willibal, K.; Burrows, N. D.; Mitchell, P.; Bakhtiiari, A.; Stanfield, S.; Pardon, E.; Kaback, H. R.; Liang, R.; Steyaert, J.; Viner, R.; Guan, L.
10.1101/2023.09.18.558283 — molecular biology — Posted on 2023-11-25
824 Alpha 9 integrin expression enables reconstruction of the spinal cord sensory pathway.
Stepankova, K.; Smejkalova, B.; Machova Urdzikova, L.; Havelikova, K.; Verhaagen, J.; deWinter, F.; Herynek, V.; Kwok, J. C. F.; Fawcett, J. C. F.; Jendelova, P.
10.1101/2023.03.24.534172 — neuroscience — Posted on 2023-11-25
826 Reproducible Neuronal Components found using Group Independent Component Analysis in Resting State Electroencephalographic Data
Ochoa-Gomez, J. F.; Mantilla Ramos, Y. J.; Henao Isaza, V.; Tobon, C. A.; Lopera, F.; Aguillon, D.; Suarez Revelo, J. X.
10.1101/2023.11.14.566952 — neuroscience — Posted on 2023-11-25
827 Imaging Microglia Surveillance during Sleep-wake Cycles in Freely Behaving Mice
Gu, X.; Zhao, Z.; Chen, X.; Zhang, L.; Fang, H.; Zhao, T.; Ju, S.; Gao, W.; Qian, X.; Wang, X.; Zhang, J.; Cheng, H.
10.1101/2023.02.03.527083 — neuroscience — Posted on 2023-11-25
835 Seedling microbiota engineering using bacterial synthetic community inoculation on seeds
Arnault, G.; Marais, C.; Preveaux, A.; Briand, M.; Poisson, A.-S.; Sarniguet, A.; Barret, M.; Simonin, M.
10.1101/2023.11.24.568582 — ecology — Posted on 2023-11-24
837 Identifying the seizure onset zone with intracranial EEG: A systematic comparison between power and connectivity-based biomarkers
Vila-Vidal, M.; Corominas, F. C.-B.; Gilson, M.; Zucca, R.; Principe, A.; Rocamora, R.; Deco, G.; Campo, A. T.
10.1101/2023.11.23.568472 — neuroscience — Posted on 2023-11-24
838 Longitudinal trajectories of the neural encoding mechanisms of speech-sound features during the first year of life
Puertollano, M.; Ribas-Prats, T.; Gorina-Careta, N.; Ijjou-Kadiri, S.; Arenillas-Alcon, S.; Mondejar-Segovia, A.; Gomez-Roig, M. D.; Escera, C.
10.1101/2023.11.24.567803 — neuroscience — Posted on 2023-11-24
839 A deep learning convolutional neural network distinguishes neuronal models of Parkinson's disease from matched controls
Thomas, R. A.; Cai, E.; Reintsch, W.; Han, C.; Shinde, S.; Lariviere, R.; Krahn, A.; Chen, C. X. Q.; Nguyen-Renou, E.; Deneault, E.; You, Z.; Durcan, T. M.; Fon, E. A.
10.1101/2023.11.23.568499 — neuroscience — Posted on 2023-11-24
841 Stimulating prefrontal cortex facilitates training transfer by increasing representational overlap
Wards, Y.; Ehrhardt, S. E.; Filmer, H. L.; Mattingley, J. B.; Garner, K. G.; Dux, P. E.
10.1101/2023.11.23.568508 — neuroscience — Posted on 2023-11-24
847 Defective Integrator activity shapes the transcriptome of patients with multiple sclerosis
Porozhan, Y.; Carstensen, M.; Thouroude, S.; Costallat, M.; Rachez, C.; Batsche, E.; Petersen, T.; Christensen, T.; Muchardt, C.
10.1101/2023.11.24.568591 — genomics — Posted on 2023-11-24
849 Embryonic lymphocytes contribute to a genetic form of autoimmune inflammation
Cascione, S.; Fontana, E.; Scarfo, R.; Rigoni, R.; Capo, V.; Draghici, E.; Dobbs, K.; Villa, A.; Notarangelo, L. D.; Ditadi, A.
10.1101/2023.11.24.568475 — developmental biology — Posted on 2023-11-24
850 ADNP Modulates SINE B2-Derived CTCF-Binding Sites during Blastocyst Formation in Mouse
Wang, W.; Gao, R.; Yang, D.; Ma, M.; Zang, R.; Wang, X.; Chen, C.; Chen, J.; Kou, X.; Zhao, Y.; Liu, X.; Wang, H.; Gao, Y.; Zhang, Y.; Gao, S.
10.1101/2023.11.24.567719 — developmental biology — Posted on 2023-11-24
855 CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23
Gruschow, S.; McQuarrie, S.; Ackermann, K.; McMahon, S.; Bode, B.; Gloster, T. M.; White, M. F.
10.1101/2023.11.24.568546 — microbiology — Posted on 2023-11-24
856 Increased FAN1 expression by mRNA-LNP attenuates CAG repeat expansion in Huntington patients' iPSC-derived astrocytes
Cheng, Y.-C.; Nocula-Lugowska, G.; Ramirez, J. A.; Fan, X.; Jin, F.; Jiang, Z.; Bennett, E.; Li, J.; Hokanson, D.; Grandhi, S.; Chen, M.; Cheng, C.; Lin, G.-Y.; Lin, L.; Lepsy, C.; Chaparro-Riggers, J.; Bloom, L.; Morrissey, D.; Stewart, M.; Tadin-Strapps, M.; Chiang, S.-H.
10.1101/2023.11.24.568451 — neuroscience — Posted on 2023-11-24
857 Preoptic area controls sleep-related seizure onset in a genetic epilepsy mouse model
Potesta, C. V.; Cargile, M. S.; Yan, A.; Macdonald, R. L.; Gallagher, M. J.; Zhou, C.
10.1101/2023.11.24.568593 — neuroscience — Posted on 2023-11-24
858 Age-related structural and functional changes of the intracardiac nervous system
Hortells, L.; Zgierski-Johnston, C. M.; Kohl, P.; Schneider-Warme, F.; Ravens, U.; Preissl, S.; Cameron, B. A.; Koch, M.; Brennan, T. A.; Madl, J.; Iaconianni, P.; Fernandez, M. C.; Stefanovska, D.; Tumlinson, G.; Sassu, E.
10.1101/2023.11.24.568538 — physiology — Posted on 2023-11-24
859 Nanopore and Illumina Sequencing Reveal Different Viral Populations from Human Gut Samples
Cook, R.; Telatin, A.; Hsieh, S.-Y.; Newberry, F.; Tariq, M. A.; Baker, D. J.; Carding, S. R.; Adriaenssens, E. M.
10.1101/2023.11.24.568560 — bioinformatics — Posted on 2023-11-24
862 A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors
Menon, I.; Sych, T.; Son, Y.; Morizumi, T.; Lee, J.; Ernst, O. P.; Khelashvili, G.; Sezgin, E.; Levitz, J.; Menon, A. K.
10.1101/2023.11.24.568580 — biochemistry — Posted on 2023-11-24
870 Feedback control of organ size precision is mediated by BMP2-regulated apoptosis in the Drosophila eye
Navarro, T.; Iannini, A.; Neto, M.; Campoy-Lopez, A.; Munoz-Garcia, J.; Pereira, P. S.; Ares, S.; Casares, F.
10.1101/2023.03.02.530805 — developmental biology — Posted on 2023-11-24
871 Epidermal clock integration and gating of brain signals guarantees skin homeostasis
Mortimer, T.; Zinna, V. M.; Atalay, M.; Laudanna, C.; Deryagin, O.; Smith, J. G.; Garcia-Lara, E.; Vaca-Dempere, M.; Koronowski, K. B.; Petrus, P.; Greco, C. M.; Forrow, S.; Sassone Corsi, P.; Welz, P.-S.; Munoz Canoves, P.; Aznar Benitah, S.
10.1101/2022.01.26.477844 — cell biology — Posted on 2023-11-24
872 Thyroid Hormone T4 Mitigates Traumatic Brain Injury by Dynamically Remodeling Cell Type Specific Genes, Pathways, and Networks in Hippocampus and Frontal Cortex
Zhang, G.; Diamante, G.; Ahn, I.; Palafox-Sanchez, V.; Cheng, J.; Cheng, M.; Ying, Z.; Wang, S. S.-M.; Abuhanna, K. D.; Phi, N.; Arneson, D.; Cely, I.; Arellano, K.; Wang, N.; Gomez-Pinilla, F.; Yang, X.
10.1101/2022.11.15.516648 — neuroscience — Posted on 2023-11-24
876 Consistent individual positions within roosts in Spix's disc-winged bats
Giacomini, G.; Chaves-Ramirez, S.; Hernandez-Pinson, A.; Barrantes, J. P.; Chaverri, G.
10.1101/2022.11.04.515223 — ecology — Posted on 2023-11-24
879 Platelet-derived transcription factors license human monocyte 1 inflammation
Hawwari, I.; Rosero, N.; Maasewerd, S.; Jentzsch, M.; Demczuk, A.; Ribeiro, L. S.; Teichmann, L. S.; Meffert, L.; Kallabis, S.; Meissner, F.; Noval Rivas, M.; Arditi, M. A.; Bertheloot, D.; Franklin, B. S.
10.1101/2022.08.10.503291 — immunology — Posted on 2023-11-24
880 Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism
Arbogast, F.; Sal-Carro, R.; Boufenghour, W.; Frenger, Q.; Bouis, D.; Filippi de la Palavesa, L.; Fauny, J.-D.; Griso, O.; Puccio, H.; Fima, R.; Huby, T.; Gautier, E. L.; Molitor, A.; Carapito, R.; Bahram, S.; Romani, N.; Clausen, B. E.; Voisin, B.; Mueller, C. G.; Gros, F.; Flacher, V.
10.1101/2022.09.16.507799 — immunology — Posted on 2023-11-24
881 Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia
Monzel, M.; Leelaarporn, P.; Lutz, T.; Schultz, J.; Brunheim, S.; Reuter, M.; McCormick, C.
10.1101/2023.08.11.552915 — neuroscience — Posted on 2023-11-24
883 BdNRT2A and BdNRT3.2 are the major components of the High-Affinity nitrate Transport System in Brachypodium distachyon
David, L. C.; Gregoire, M.; Berquin, P.; Marmagne, A.; Dalmais, M.; Bendahmane, A.; Miller, A. J.; Krapp, A.; Daniel-Vedele, F.; Girin, T.; FERRARIO-MERY, S.
10.1101/2023.11.24.567652 — plant biology — Posted on 2023-11-24
885 Isogenic iPSC-derived proximal and distal lung-on-chip models: Tissue- and virus-specific immune responses in human lungs
Yadav, S.; Fujimoto, K.; Takenaga, T.; Takahashi, S.; Muramoto, Y.; Mikawa, R.; Noda, T.; Gotoh, S.; Yokokawa, R.
10.1101/2023.11.24.568532 — bioengineering — Posted on 2023-11-24
886 Role of the medial agranular cortex in unilateral spatial neglect
Ishii, D.; Osaki, H.; Yozu, A.; Yamamoto, T.; Yamamoto, S.; Miyata, M.; Kohno, Y.
10.1101/2023.11.24.568203 — animal behavior and cognition — Posted on 2023-11-24
888 Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
Garcia-Cuesta, E. M.; Martinez, P.; Selvaraju, K.; Gomez Pozo, A. M.; D'Agostino, G.; Gardeta, S.; Quijada-Freire, A.; Blanco Gabella, P.; Roca, C.; Jimenez-Saiz, R.; Garcia-Rubia, A.; Soler Palacios, B.; Lucas, P.; Ayala-Bueno, R.; Santander Acerete, N.; carrasco, y.; Martinez, A.; Campillo, N. E.; Jensen, L. D.; Rodriguez Frade, J. M.; Santiago, C.; Mellado, M.
10.1101/2023.11.19.567737 — cell biology — Posted on 2023-11-24
890 Transcription termination by RNA polymerase I
Turowski, T. W.; Petfalski, E.; Winz, M.-L.; Tollervey, D.
10.1101/2023.11.24.568579 — molecular biology — Posted on 2023-11-24
894 Primate origins of human event cognition
Wilson, V. A. D.; Sauppe, S.; Brocard, S.; Ringen, E. J.; Daum, M. M.; Wermelinger, S.; Gu, N.; Andrews, C.; Isasi-Isasmendi, A.; Bickel, B.; Zuberbuehler, K.
10.1101/2023.11.23.568086 — animal behavior and cognition — Posted on 2023-11-24
895 Hurricanes Pose Substantial Risk to New England Forest Carbon Stocks
Tumber-Davila, S. J.; Lucey, T.; Boose, E.; Laflower, D.; Leon-Saenz, A.; Wilson, B. T.; MacLean, M. G.; Thompson, J.
10.1101/2023.11.22.568264 — ecology — Posted on 2023-11-24
896 Detection and spread of high pathogenicity avian influenza virus H5N1 in the Antarctic Region
Bennison, A.; Byrne, A. M.; Reid, S. M.; Lynton-Jenkins, J. G.; Mollett, B.; De Sliva, D.; Peers-Dent, J.; Finlayson, K. E.; Hall, R.; Blockley, F.; Blyth, M.; Falchieri, M.; Fowler, Z.; Fitzcharles, E.; Brown, I. H.; James, J.; Banyard, A. C.
10.1101/2023.11.23.568045 — microbiology — Posted on 2023-11-24
898 Epstein Barr virus infection induces tissue-resident memory T cells in mucosal lymphoid tissues
Kirchmeier, D.; Deng, Y.; Rieble, L.; Laderach, F.; Schuhmachers, P.; Valencia-Camargo, A. D.; Murer, A.; Caduff, N.; Chatterjee, B.; Chijioke, O.; Zens, K.; Munz, C.
10.1101/2023.11.24.565960 — immunology — Posted on 2023-11-24
903 Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA
Holvec, S.; Barchet, C.; Lechner, A.; Frechin, L.; De Silva, S. N. T.; Hazemann, I.; Wolff, P.; von Loeffelholz, O.; Klaholz, B. P.
10.1101/2023.11.23.568509 — biochemistry — Posted on 2023-11-24
905 Avian influenza viruses in wild birds in Canada following incursion of the highly pathogenic H5N1 virus from Eurasia in 2021/2022
Giacinti, J. A.; Signore, A. V.; Jones, M. E. B.; Bourque, L.; Lair, S.; Jardine, C.; Stevens, B.; Bollinger, T.; Goldsmith, D.; British Columbia Wildlife AIV Surveillance Program (BC WASP), ; Pybus, M.; Stasiak, I.; Davis, R.; Pople, N.; Nituch, L.; Brook, R. W.; Ojkic, D.; Masse, A.; Dimitri-Masson, G.; Parsons, G. J.; Baker, M.; Yason, C.; Harms, J.; Jutha, N.; Neely, J.; Berhane, Y.; Lung, O.; French, S. K.; Myers, L.; Provencher, J. F.; Avery-Gomm, S.; Robertson, G. J.; Barychka, T.; Gurney, K. E. B.; Wight, J.; Rahman, I.; Hargan, K.; Lang, A. S.; Brown, M. G. C.; Pekarik, C.; Thompson,
10.1101/2023.11.23.565566 — zoology — Posted on 2023-11-24
908 An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors
Fernandes Silva, S.; Klippel, A. H.; Sigurdardottir, S.; Mahdizadeh, S. J.; Tiukova, I.; Bourgard, C.; Monteiro do Amaral Prado, H.; de Araujo, R. V.; Bilsland, E.; King, R.; Massirer, K. B.; Eriksson, L.; Bengtson, M. H.; Sunnerhagen, P.; Zanelli, C. F.
10.1101/2023.11.23.568514 — synthetic biology — Posted on 2023-11-24
910 Unmasking Hidden Systemic Effects of Neurodegenerative Diseases: A Two-Pronged Approach to Biomarker Discovery
Anjo, S. I.; Rosado, M.; Baldeiras, I.; Gomes, A.; Pires, D.; Santa, C.; Pinto, J.; Januario, C.; Santana, I.; Verdelho, A.; Mendonca, A. d.; Castelo-Branco, M.; Manadas, B.
10.1101/2023.11.23.568435 — biochemistry — Posted on 2023-11-24
912 LISA: A Case For Learned Index based Acceleration of Biological Sequence Analysis
Ho, D.; Kalikar, S.; Misra, S.; Ding, J.; Md, V.; Tatbul, N.; Li, H.; Kraska, T.
10.1101/2020.12.22.423964 — bioinformatics — Posted on 2023-11-24
916 Cyclic and pseudo-cyclic electron pathways play antagonistic roles during nitrogen deficiency in Chlamydomonas reinhardtii
Dao, O.; Burlacot, A.; Buchert, F.; Bertrand, M.; Auroy, P.; Stoffel, C.; Irby, J.; Hippler, M.; Peltier, G.; Li-Beisson, Y.
10.1101/2023.01.18.524499 — plant biology — Posted on 2023-11-24
920 Phenotypic stasis with genetic divergence
Mallard, F.; Noble, L.; Guzella, T.; Afonso, B.; Baer, C. F.; Teotonio, H.
10.1101/2022.05.28.493856 — evolutionary biology — Posted on 2023-11-23
921 Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult Mice
Tai, W. L.; Cho, K.-S.; Kriukov, E.; Ashok, A.; Wang, X.; Monavarfeshani, A.; Yan, W.; Li, Y.; Guan, T.; Sanes, J. R.; Baranov, P.; Chen, D. F.
10.1101/2023.11.17.567614 — neuroscience — Posted on 2023-11-23
923 StayGold Photostability under Different Illumination Modes
Hirano, M.; Yonemaru, Y.; Shimozono, S.; Sugiyama, M.; Ando, R.; Okada, Y.; Fujiwara, T.; Miyawaki, A.
10.1101/2023.11.23.568490 — cell biology — Posted on 2023-11-23
925 Benchmarking sample pooling for epigenomics of natural populations
Daniels, R. J.; Meyer, B.; Giulio, M.; Signorini, S.; Riccardi, N.; Della Torre, C.; Weber, A.
10.1101/2023.11.23.568483 — genomics — Posted on 2023-11-23
926 A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X
Jowhar, Z.; Xu, A.; Venkataramanan, S.; Dossena, F.; Hoye, M. L.; Silver, D. L.; Floor, S. N.; Calviello, L.
10.1101/2023.05.11.540322 — genomics — Posted on 2023-11-23
929 CRONOSOJA: a daily time-step hierarchical model predicting soybean development across maturity groups in the Southern Cone
Severini, A. D.; Alvarez-Prado, S.; Otegui, M. E.; Kavanova, M.; Vega, C.; Zuil, S.; Ceretta, S.; Acreche, M. M.; Amarilla, F.; Cicchino, M. A.; Fernandez Long, M. E.; Crespo, A. O.; Serrago, R.; Miralles, D. J.
10.1101/2023.09.18.558336 — plant biology — Posted on 2023-11-23
930 Automated cell annotation in multi-cell images using an improved CRF_ID algorithm
Lee, H. J.; Liang, J.; Chaudhary, S.; Moon, S.; Yu, Z.; Wu, T.; Liu, H.; Choi, M.-K.; Zhang, Y.; Lu, H.
10.1101/2023.06.07.543949 — bioengineering — Posted on 2023-11-23
932 Ocean-scale variation in migration schedules of a long-distance migratory seabird is fully compensated upon return to the breeding site
van Bemmelen, R. S. A.; Moe, B.; Schekkerman, H.; Hansen, S. A.; Snell, K. R. S.; Humphreys, E. M.; Mantyla, E.; Hallgrimsson, G. T.; Gilg, O.; Ehrich, D.; Calladine, J.; Hammer, S.; Harris, S. J.; Lang, J.; Vignisson, S. R.; Kolbeinsson, Y.; Nuotio, K.; Sillanpaa, M.; Sittler, B.; Sokolov, A.; Klaassen, R. H. G.; Phillips, R. A.; Tulp, I.
10.1101/2023.05.27.542544 — ecology — Posted on 2023-11-23
935 Platelet-derived transcription factors license human monocyte 1 inflammation
Hawwari, I.; Rosero, N.; Maasewerd, S.; Jentzsch, M.; Demczuk, A.; Ribeiro, L. S.; Teichmann, L. S.; Meffert, L.; Kallabis, S.; Meissner, F.; Noval Rivas, M.; Arditi, M. A.; Bertheloot, D.; Franklin, B. S.
10.1101/2022.08.10.503291 — immunology — Posted on 2023-11-23
937 Mining the neuroimaging literature
Dockes, J.; Oudyk, K. M.; Torabi, M.; De La Vega, A. I.; Poline, J.-B.
10.1101/2023.10.30.564783 — neuroscience — Posted on 2023-11-23
938 Loss of cardiac PFKFB2 drives Metabolic, Functional, and Electrophysiological Remodeling in the Heart
Harold, K. M.; Matsuzaki, S.; Pranay, A.; Loveland, B. L.; Batushansky, A.; Mendez Garcia, M. F.; Eyster, C. A.; Stavrakis, S.; Chiao, Y. A.; Kinter, M.; Humphries, K. M.
10.1101/2023.11.22.568379 — physiology — Posted on 2023-11-23
939 Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness
Amelink, J. S.; Postema, M. C.; Kong, X.-Z.; Schijven, D.; Carrion-Castillo, A.; Soheili-Nezhad, S.; Sha, Z.; Molz, B.; Joliot, M.; Fisher, S. E.; Francks, C.
10.1101/2023.11.22.568256 — genomics — Posted on 2023-11-23
940 Cadherins modulate the self-organizing potential of gastruloids
Mayran, A.; Kolly, D.; Lopez-Delisle, L.; Romaniuk, Y.; Leonardi, M.; Cossy, A.-C.; Lacroix, T.; Amandio, A.-R.; Osteil, P.; Duboule, D.
10.1101/2023.11.22.568291 — developmental biology — Posted on 2023-11-23
941 pHusion: A robust and versatile toolset for automated detection and analysis of exocytosis
O'Shaughnessy, E. C.; Lam, M.; Ryken, S. E.; Wiesner, T.; Lukasik, K.; Zuchero, J. B.; Leterrier, C.; Adalsteinsson, D.; Gupton, S. L.
10.1101/2023.07.25.550499 — cell biology — Posted on 2023-11-23
942 Plant Phenolics Inhibit Focal Adhesion Kinase and Suppress Host Cell Invasion by Uropathogenic Escherichia coli
Lewis, A. J.; Richards, A. C.; Mendez, A. A.; Dhakal, B. K.; Jones, T. A.; Sundsbak, J. L.; Eto, D. S.; Mulvey, M. A.
10.1101/2023.11.23.568486 — microbiology — Posted on 2023-11-23
948 IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections
Creusat, F.; Jouan, Y.; Gonzalez, L.; Barsac, E.; Ilango, G.; Lemoine, R.; Soulard, D.; Boisseau, C.; Guillon, A.; Lin, Q.; de Amat Herbozo, C.; Sencio, V.; Winter, N.; Trottein, F.; Si-Tahar, M.; Briard, B.; Mallevaey, T.; Faveeuw, C.; Baranek, T.; Paget, C.
10.1101/2023.11.23.568456 — immunology — Posted on 2023-11-23
951 Anatomical insights into the vascular lay-out of the barley rachis: implications for transport and spikelet connection
Rutten, T.; Thirulogachandar, V.; Huang, Y.; Shanmugaraj, N.; Koppolu, R.; Ortleb, S.; Hensel, G.; Kumlehn, J.; Melzer, M.; Schnurbusch, T.
10.1101/2023.11.23.568454 — plant biology — Posted on 2023-11-23
955 Synthesis and characterization of novel intrinsically fluorescent analogs of cholesterol with improved photophysical properties.
Lehmann, M.; Reinholdt, P.; Bashawat, M.; Scheidt, H. A.; Halder, S.; di Prima, D.; Kongsted, J.; Müller, P.; Wessig, P.; Wüstner, D.
10.1101/2023.11.23.568457 — biophysics — Posted on 2023-11-23
956 Kinex infers causal kinases from phosphoproteomics data
Valeanu, A.; Golz, V.; Avila, D. W.; Tzouros, M.; Siebourg-Polster, J.; Badi, L.; Zhang, J. D.
10.1101/2023.11.23.568445 — bioinformatics — Posted on 2023-11-23
961 Population genomic history of the endangered Anatolian and Cyprian mouflons in relation to worldwide wild, feral and domestic sheep lineages
Atag, G.; Kaptan, D.; Yüncü, E.; Vural, K. B.; Mereu, P.; Pirastru, M.; Barbato, M.; Leoni, G. G.; Güler, M. N.; Er, T.; Eker, E.; Yazıcı, T. D.; Kılıc, M. S.; Altınısık, N. E.; Celik, E. A.; Miranda, P. M.; Dehasque, M.; Floridia, V.; Götherström, A.; Bilgin, C. C.; Togan, I.; Günther, T.; Özer, F.; Hadjisterkotis, E.; Somel, M.
10.1101/2023.11.23.568468 — evolutionary biology — Posted on 2023-11-23
962 Multi-level framework to assess social variation in response to ecological and social factors: modeled with coral gobies
Froehlich, C. Y. M.; Heatwole, S. J.; Klanten, O. S.; Hing, M. L.; Hildebrandt, C. A.; Smith, J. O.; Wong, M. Y. L.
10.1101/2023.11.22.568347 — ecology — Posted on 2023-11-23
965 Coral reef potential connectivity in the southwest Indian Ocean
Vogt-Vincent, N. S.; Burt, A. J.; van der Ven, R. M.; Johnson, H. L.
10.1101/2023.11.23.568484 — ecology — Posted on 2023-11-23
966 E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled family members
Bugter, J. M.; van Kerkhof, P.; Janssen, E.; Tran Ngoc Minh, T.; Iglesias van Montford, D.; Jamieson, C.; Jordens, I.; Maurice, M. M.
10.1101/2023.11.23.568206 — cell biology — Posted on 2023-11-23
968 Predictive phage therapy for Escherichia coli urinary tract infections: cocktail selection for therapy based on machine learning models
Keith, M.; Park de la Torriente, A.; Chalka, A.; Vallejo-Trujillo, A.; McAteer, S. P.; Paterson, G. K.; Low, A. S.; Gally, D. L.
10.1101/2023.11.23.568453 — microbiology — Posted on 2023-11-23
983 Towards modeling genome-scale knowledge in the global ocean
Regimbeau, A.; Aumont, O.; Bowler, C.; Guidi, L.; Jackson, G. A.; Karsenti, E.; Memery, L.; Tagliabue, A.; Eveillard, D.
10.1101/2023.11.23.568447 — bioinformatics — Posted on 2023-11-23
987 Gaining Biological Insights through Supervised Data Visualization
Rhodes, J. S.; Aumon, A.; Morin, S.; Girard, M.; Larochelle, C.; Lahav, B.; Brunet-Ratnasingham, E.; Zhang, W.; Cutler, A.; Zhou, A.; Kaufmann, D. E.; Zandee, S.; Prat, A.; Wolf, G.; Moon, K. R.
10.1101/2023.11.22.568384 — bioinformatics — Posted on 2023-11-23
989 Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing
Wan, J.; Nie, Z.; Xu, J.; Zhang, Z.; Yao, S.; Xiang, Z.; Lin, X.; Lu, Y.; Xu, C.; Zhao, P.; Wang, Y.; Zhang, J.; Wang, Y.; Zhang, S.; Wang, J.; Man, W.; Zhang, M.; Han, M.
10.1101/2023.11.23.568392 — bioengineering — Posted on 2023-11-23
991 Fluorescent human RPA to track assembly dynamics on DNA
Kaushik, V.; Chadda, R.; Kuppa, S.; Pokhrel, N.; Vayyeti, A.; Grady, S.; Arnatt, C.; Antony, E.
10.1101/2023.11.23.568455 — biochemistry — Posted on 2023-11-23
992 Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling
Mehrabipour, M.; Dvorsky, R.; Nakhaei-Rad, S.; Lang, A.; Verhuelsdonk, P.; Ahmadian, M. R.; Piekorz, R. P.
10.1101/2023.11.23.568463 — biochemistry — Posted on 2023-11-23
997 Enhanced surface accessibility of SARS-CoV-2 Omicron spike protein due to an altered glycosylation profile
Wang, D.; Zhang, Z.; Baudys, J.; Haynes, C. A.; Osman, S. H.; Zhou, B.; Barr, J. R.; Gumbart, J. C.
10.1101/2023.11.22.568381 — molecular biology — Posted on 2023-11-23
1000 Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart
Guevara, A.; Smith, C. E. R.; Caldwell, J. L.; Ngo, L.; Mott, L. R.; Lee, I.-J.; Tapa, S.; Wang, Z.; Wang, L.; Woodward, W. R.; Ng, G. A.; Habecker, B. A.; Ripplinger, C. M.
10.1101/2023.11.23.567754 — physiology — Posted on 2023-11-23
1003 Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid
Zhao, H.; Syed, A. M.; Khalid, M. M.; Nguyen, A.; Ciling, A.; Wu, D.; Yau, W.-M.; Srinivasan, S.; Esposito, D.; Doudna, J. A.; Piszczek, G.; Ott, M.; Schuck, P.
10.1101/2023.11.22.568361 — biophysics — Posted on 2023-11-23
1006 Adaptive gene loss in the common bean pan-genome during range expansion and domestication
Cortinovis, G.; Vincenzi, L.; Anderson, R.; Marturano, G.; Marsh, J. I.; Bayer, P. E.; Rocchetti, L.; Frascarelli, G.; Lanzavecchia, G.; Pieri, A.; Benazzo, A.; Bellucci, E.; Di Vittori, V.; Nanni, L.; Fernandez, J. J. F.; Rossato, M.; Aguilar, O. M.; Morrell, P. L.; Rodriguez, M.; Gioia, T.; Neumann, K.; Diaz, J. C. A.; Gratias-Weill, A.; Klopp, C.; Geffroy, V.; Bitocchi, E.; Delledonne, M.; Edwards, D.; Papa, R.
10.1101/2023.11.23.568464 — evolutionary biology — Posted on 2023-11-23
1009 Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry
Eggeler, F.; Boulanger-Weill, J.; De Santis, F.; Belleri, L.; Duroure, K.; Auer, T. O.; Albadri, S.; Del Bene, F.
10.1101/2023.11.23.568438 — developmental biology — Posted on 2023-11-23
1011 Development of attenuated coxsackievirus B3 vectored intranasal pre-emptive pan-coronavirus vaccine
Deng, H.; He, X.; Li, Y.; Wang, H.; Wang, S.; Gu, L.; Zhang, H.; Zhu, J.; Li, R.; Wang, G.
10.1101/2023.11.22.568225 — microbiology — Posted on 2023-11-23
1012 Tagging of water masses with covariance of trace metals and prokaryotic taxa in the Southern Ocean
Zhang, R.; Blain, S.; Baudet, C.; Planquette, H.; Vivier, F.; Catala, P.; Crispi, O.; Gueneugues, A.; Marie, B.; Debeljak, P.; Obernosterer, I.
10.1101/2023.11.23.568349 — microbiology — Posted on 2023-11-23
1016 Investigation of microglial diversity in a mouse model of Parkinson's disease pathology
Iovino, L.; VanderZwaag, J.; Kaur, G.; Khakpour, P.; Giusti, V.; Chiavegato, A.; Tenorio-Lopes, L.; Greggio, E.; Tremblay, M.-E.; Civiero, L.
10.1101/2023.11.23.567809 — neuroscience — Posted on 2023-11-23
1017 Single-cell imaging of protein dynamics of paralogs reveals mechanisms of gene retention
Dandage, R.; Papkov, M.; Greco, B. M.; Fishman, D.; Friesen, H.; Wang, K.; Styles, E.; Kraus, O.; Grys, B.; Boone, C.; Andrews, B. J.; Parts, L.; Kuzmin, E.
10.1101/2023.11.23.568466 — systems biology — Posted on 2023-11-23
1020 The bile acid receptor TGR5 regulates the hematopoietic support capacity of the bone marrow niche
Alonso-Calleja, A.; Perino, A.; Schyrr, F.; Ferreira Lopes, S.; Delitsikou, V.; Jalil, A.; Kettenberger, U.; Pioletti, D. P.; Schoonjans, K.; Naveiras, O.
10.1101/2023.11.22.568250 — cell biology — Posted on 2023-11-23
1022 An Environmental Restriction impairs HIV-1 virion fusion and triggers innate immune recognition
Sid Ahmed, S.; Zimmermann, L.; Imle, A.; Wuebben, K.; Tibroni, N.; Rauch-Wirth, L.; Muench, J.; Chlanda, P.; Graw, F.; Fackler, O. T.
10.1101/2023.11.22.568261 — immunology — Posted on 2023-11-23
1023 GDF15 mediates inflammation-associated bone loss through a brain-bone axis
Van der Cruyssen, R.; Devan, J.; Heggli, I.; Burri, D.; Gaublomme, D.; Josipovic, I.; Dumas, E.; Vlieghe, C.; Raimondo, M. G.; Zakharov, P.; Jacques, P.; De Mits, S.; Lukasik, Z.; Vuylsteke, M.; Renson, T.; Schots, L.; Planckaert, G.; Stappers, F.; Decruy, T.; Coudenys, J.; Manuello, T.; Vereecke, L.; Dmitriev, R. I.; Lambrecht, S.; Van Hoorebeke, L.; Lambert, J.; Ravichandran, K.; Ramming, A.; Dudli, S.; Schett, G.; Gracey, E.; Elewaut, D.
10.1101/2023.11.22.568290 — immunology — Posted on 2023-11-23
1027 Cancer-associated fibroblasts serve as decoys to suppress NK cell anti-cancer cytotoxicity
Ben-Shmuel, A.; Gruper, Y.; Levi-Galibov, O.; Rosenberg-Fogler, H.; Carradori, G.; Stein, Y.; Dadiani, M.; Naumova, M.; Nevo, R.; Morzaev-Sulzbach, D.; Yagel, G.; Mayer, S.; Gal-Yam, E.; Scherz-Shouval, R.
10.1101/2023.11.23.568355 — cancer biology — Posted on 2023-11-23
1030 The Sec61/TRAP Translocon Scrambles Lipids
Javanainen, M.; Karki, S.; Tranter, D.; Biriukov, D.; Paavilainen, V. O.
10.1101/2023.11.23.568215 — biophysics — Posted on 2023-11-23
1031 Semi-supervised learning and large-scale docking data accelerate RNA virtual screening
Carvajal-Patino, J. G.; Mallet, V.; Becerra, D.; Nino, L. F.; Oliver, C.; Waldispuhl, J.
10.1101/2023.11.23.568394 — bioinformatics — Posted on 2023-11-23
1032 Exploring the family feud: a fungal endophyte induces local cell wall-mediated resistance in wheat roots against the closely related "take-all" pathogen
Chancellor, T.; Smith, D. P.; Chen, W.; Clark, S. J.; Venter, E.; Halsey, K.; McMillan, V.; Canning, G.; Hammond-Kosack, K. E.; Palma-Guerrero, J.
10.1101/2023.11.23.568424 — plant biology — Posted on 2023-11-23
1036 A liquid-like coat mediates chromosome clustering during mitotic exit
Hernandez-Armendariz, A.; Sorichetti, V.; Hayashi, Y.; Brunner, A.; Ellenberg, J.; Saric, A.; Cuylen-Haering, S.
10.1101/2023.11.23.568026 — cell biology — Posted on 2023-11-23
1038 AP-1 regulates heterogeneous cellular dormancy in TNBC
Dong, Y.; Bai, J.; Fu, R.; Su, H.; Wu, S.; Tang, D. G.; Zhou, J.
10.1101/2023.11.22.566980 — cancer biology — Posted on 2023-11-23
1041 A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth
Zuazo-Gaztelu, I.; Lawrence, D.; Oikonomidi, I.; Marsters, S.; Pechuan-Jorge, X.; Gaspar, C. J.; Kan, D.; Segal, E.; Clark, K.; Beresini, M.; Braun, M.-G.; Rudolph, J.; Modrusan, Z.; Choi, M.; Sandoval, W.; Reichelt, M.; Kujala, P.; van Dijk, S.; Klumperman, J.; Ashkenazi, A.
10.1101/2023.11.22.567905 — cancer biology — Posted on 2023-11-23
1044 Causal Role of the Medial Prefrontal Cortex in Learning Social Hierarchy
Qu, C.; Huang, Y.; Philippe, R.; Cai, S.; Derrington, E.; Moisan, F.; Shi, M.; Dreher, J.-C.
10.1101/2023.11.23.568266 — neuroscience — Posted on 2023-11-23
1046 A Novel Role for Phospholamban in the Thalamic Reticular Nucleus
Klocke, B.; Britzolaki, A.; Saurine, J.; Ott, H.; Krone, K.; Bahamonde, K.; Thelen, C.; Tzimas, C.; Sanoudou, D.; Kranias, E. G.; Pitychoutis, P. M.
10.1101/2023.11.22.568306 — neuroscience — Posted on 2023-11-23
1049 Modulation of dysbiotic vaginal complications by cervical mucus revealed in linked human vagina and cervix chips
Gutzeit, O.; GULATI, A.; IZADIFAR, Z.; STEJSKALOVA, A.; RHBINY, H.; COTTON, J.; BUDNIK, B.; SHAHRIAR, S.; GOYAL, G.; JUNAID, A.; INGBER, D. E.
10.1101/2023.11.22.568273 — systems biology — Posted on 2023-11-23
1053 Features that matter: evolutionary signatures that predict viral transmission routes
Wardeh, M.; Pilgrim, J.; Hui, M.; Kotsiri, A.; Baylis, M.; Blagrove, M. S.
10.1101/2023.11.22.568327 — ecology — Posted on 2023-11-23
1056 Loss of cardiac PFKFB2 drives Metabolic, Functional, and Electrophysiological Remodeling in the Heart
Harold, K. M.; Matsuzaki, S.; Pranay, A.; Loveland, B. L.; Batushansky, A.; Mendez Garcia, M. F.; Eyster, C. A.; Stavrakis, S.; Chiao, Y. A.; Kinter, M.; Humphries, K. M.
10.1101/2023.11.22.568379 — physiology — Posted on 2023-11-23
1057 Adherent reformed islets: a long-term primary cell-based platform for exploring mouse and human islet biology.
Haq, N.; Toczyska, K.; Wilson, M.; Jacobs, M.; Lei, Y.; Zhao, M.; Pearson, J.; Persaud, S.; Pullen, T.; Bewick, G. A.
10.1101/2023.11.22.568245 — physiology — Posted on 2023-11-23
1058 Mechanical characterization of regenerating Hydra tissue spheres
Perros, T.; Biquet-Bisquert, A.; Ben Meriem, Z.; Delarue, M.; Joseph, P.; Marcq, P.; Cochet-Escartin, O.
10.1101/2023.10.16.562504 — biophysics — Posted on 2023-11-23
1062 Taxometer: Improving taxonomic classification of metagenomics contigs
Kutuzova, S.; Nielsen, M.; Piera Lindez, P.; Nybo Nissen, J.; Rasmussen, S.
10.1101/2023.11.23.568413 — bioinformatics — Posted on 2023-11-23
1064 Expanding the GPCR-RAMP interactome
Kotliar, I. B.; Bendes, A.; Dahl, L.; Chen, Y.; Saarinen, M.; Ceraudo, E.; Dodig, T.; Uhlen, M.; Svenningsson, P.; Schwenk, J.; Sakmar, T.
10.1101/2023.11.22.568247 — biochemistry — Posted on 2023-11-23
1068 SCC3 acts as the cohesin and inhibits inter-sister chromatids repair during rice meiosis
Zhao, Y.; Ren, L.; Zhao, T.; You, H.; Miao, Y.; Liu, H.; Cao, L.; Wang, B.; Shen, Y.; Li, Y.; Tang, D.; Cheng, Z.
10.1101/2023.11.22.568373 — genetics — Posted on 2023-11-23
1074 Compact deep neural network models of visual cortex
Cowley, B. R.; Stan, P. L.; Pillow, J. W.; Smith, M. A.
10.1101/2023.11.22.568315 — neuroscience — Posted on 2023-11-23
1075 An arginine-rich nuclear localization signal (ArgiNLS) strategy for streamlined image segmentation of single-cells
Szelenyi, E. R.; Navarrete, J. S.; Murry, A. D.; Zhang, Y.; Girven, K. S.; Kuo, L.; Cline, M. M.; Bernstein, M. X.; Burdyniuk, M.; Bowler, B.; Goodwin, N. L.; Juarez, B.; Zweifel, L.; Golden, S.
10.1101/2023.11.22.568319 — neuroscience — Posted on 2023-11-23
1077 Towards new AQP4 inhibitors: ORI-TRN-002
Thormann, M.; Traube, N.; Yehia, N.; Kostler, R.; Galabova, G.; MacAulay, N.; Toft-Bertelsen, T. L.
10.1101/2023.11.22.568252 — pharmacology and toxicology — Posted on 2023-11-23
1079 MPRAbase: A Massively Parallel Reporter Assay Database
Zhao, J.; Baltoumas, F. A.; Konnaris, M. A.; Mouratidis, I.; Liu, Z.; Sims, J.; Agarwal, V.; Pavlopoulos, G. A.; Georgakopoulos-Soares, I.; Ahituv, N.
10.1101/2023.11.19.567742 — genomics — Posted on 2023-11-22
1080 Feasibility of improving manufacturability based on protein engineering
Capito, F.; Wong, T. H.; Faust, C.; Brand, K.; Dittrich, W.; Sommerfeld, M.; Langer, T.
10.1101/2023.11.23.568267 — bioengineering — Posted on 2023-11-23
1081 Whole-genome Studies of Malagasy People Uncover Novel Body Composition Associations
Hamid, I.; Raveloson, S. N. S.; Spiral, G. J.; Ravelonjanahary, S.; Raharivololona, B. M.; Randria, J. M.; Zafimaro, M.; Randriambola, T. A.; Andriantsoa, R. M.; Andriamahefa, T. J.; Rafidison, B. F. L.; Mughal, M.; Emde, A.-K.; Hendershott, M.; LeBaron von Baeyer, S.; Wasik, K. A.; Ranaivoarisoa, J. F.; Yerges-Armstrong, L.; Castel, S. E.; Rakotoarivony, R.
10.1101/2023.11.21.568192 — genomics — Posted on 2023-11-23
1084 baRulho: an R package to quantify degradation in animal acoustic signals
Araya-Salas, M.; Grabarczyk, E. E.; Quiroz-Oliva, M.; Garcia-Rodriguez, A.; Rico-Guevara, A.
10.1101/2023.11.22.568305 — evolutionary biology — Posted on 2023-11-22
1089 The physiological costs of spatial positioning and leadership in collective movements
Brandl, H. B.; Klarevas-Irby, J. A.; Zuniga, D.; Wheat, C. H.; Christensen, C.; Omengo, F.; Nzomo, C.; Cherono, W.; Nyaguthii, B.; Farine, D. R.
10.1101/2023.11.22.567987 — ecology — Posted on 2023-11-22
1090 Connecting the dots: applying multispecies connectivity in marine park networkplanning
Gates, K.; Sandoval-Castillo, J. B.; Barcelo, A.; Bertram, A.; Pratt, E.; Moller, L.; Teske, P.; Beheregaray, L. B.
10.1101/2023.11.22.568386 — ecology — Posted on 2023-11-22
1091 Using Environmental DNA to Reconstruct Amphibian Communities at Sites Infected with Batrachochytrium salamandrivorans in the Netherlands
Davison, A.; Spitzen-van der Sluijs, A.; O'Donnell, M.; Prasetyo, A.; Broadhurst, H.; Sales, N.; Herder, J.; Coscia, I.; McDevitt, A.
10.1101/2023.11.22.568296 — ecology — Posted on 2023-11-23
1097 Unravelling Biosynthesis and Biodegradation Potentials of Microbial Dark Matters in Hypersaline Lakes
Qiu, Z.; Zhu, Y.; Zhang, Q.; Qiao, X.; Mu, R.; Xu, Z.; Yan, Y.; Wang, F.; Zhang, T.; Yu, K.
10.1101/2023.06.28.546814 — microbiology — Posted on 2023-11-23
1099 Genome sequence and cell biological toolbox of the highly regenerative, coenocytic green feather alga Bryopsis
Ochiai, K. K.; Hanawa, D.; Ogawa, H. A.; Tanaka, H.; Uesaka, K.; Edzuka, T.; Shirae-Kurabayashi, M.; Toyoda, A.; Itoh, T.; Goshima, G.
10.1101/2023.11.22.568388 — plant biology — Posted on 2023-11-23
1103 Impact of blood meals taken on ivermectin-treated livestock on survival and fecundity of the malaria vector Anopheles coluzzii under laboratory conditions
Pooda, S. H.; Hien, D. F. d. S.; Pagabeleguem, S.; Heinrich, A. P.; Porciani, A.; Sagna, A. B.; Zela, L.; Percoma, L.; Lefevre, T.; Dabire, R. K.; Koffi, A. A.; Düering, R.-A.; Pennetier, C.; Moiroux, N.; Mouline, K.
10.1101/2023.11.22.568228 — systems biology — Posted on 2023-11-22
1106 Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness
Amelink, J. S.; Postema, M. C.; Kong, X.-Z.; Schijven, D.; Carrion-Castillo, A.; Soheili-Nezhad, S.; Sha, Z.; Molz, B.; Joliot, M.; Fisher, S. E.; Francks, C. E.
10.1101/2023.11.22.568256 — genomics — Posted on 2023-11-22
1109 Pulmonary Matrix Derived Hydrogels from Patients with Idiopathic Pulmonary Fibrosis Induce a Proinflammatory State in Lung Fibroblasts In Vitro
Fernandez Davila, J. G.; Moore, D. W.; Kim, J.; Khan, J. A.; Singh, A. K.; Lemma, M.; King, C. S.; Nathan, S. D.; Rodriguez, L. R.; Grant, G. M.; Moran, J. L.
10.1101/2023.05.03.539323 — molecular biology — Posted on 2023-11-22
1113 Spatial and temporal profiling of the complement system uncovered novel functions of the alternative complement pathway in brain development
Zhang, Y.; Watson, B.; Rattan, A.; Lee, T.; Chawla, S.; Geistlinger, L.; Guan, Y.; Ma, M.; Caldarone, B. J.; Song, W.; Moffitt, J. R.; Carroll, M. C.
10.1101/2023.11.22.568325 — neuroscience — Posted on 2023-11-22
1118 CO2 Response Screen in Grass Brachypodium Reveals Key Role of a MAP-Kinase in CO2-Triggered Stomatal Closure
Lopez, B. N. K.; Ceciliato, P. H. O.; Rangel, F. J.; Salem, E. A.; Kernig, K.; Takahashi, Y.; Chow, K.; Zhang, L.; Sidhom, M. A.; Seitz, C. G.; Sibout, R.; Laudencia-Chingcuanco, D. L.; Woods, D. P.; McCammon, J. A.; Vogel, J. P.; Schroeder, J. I.
10.1101/2023.09.28.559842 — plant biology — Posted on 2023-11-22
1123 Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Wise, C.; Yu, H.; Khanshour, A. M.; Ushiki, A.; Otomo, N.; Koike, Y.; Einarsdottir, E.; Fan, Y.; Antunes, L.; Kidane, Y. H.; Cornelia, R.; Sheng, R.; Zhang, Y.; Pei, J.; Grishin, N. V.; Evers, B. M. V.; Cheung, J. P. Y.; Herring, J. A.; Terao, C.; Song, Y.-Q.; Gurnett, C.; Gerdhem, P.; Ikegawa, S.; Rios, J. J.; Ahituv, N.
10.1101/2023.05.26.542293 — genetics — Posted on 2023-11-22
1124 The IRE1α/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle
Joshi, A. S.; Da Silva, M. T.; Roy, A.; Koike, T. E.; Wu, M.; Castillo, M. B.; Gunaratne, P. H.; Liu, Y.; Iwawaki, T.; Kumar, A.
10.1101/2023.09.26.559625 — cell biology — Posted on 2023-11-22
1125 A TOPBP1 Allele Causing Male Infertility Uncouples XY Silencing Dynamics From Sex Body Formation
Ascencao, C. F. R.; Sims, J.; Dziubek, A.; Comstock, W.; Fogarty, E. A.; Badar, J.; Freire, R.; Grimson, A.; Weiss, R. S.; Cohen, P. E.; Smolka, M. B.
10.1101/2023.05.31.543071 — cell biology — Posted on 2023-11-22
1127 Taste triggers a homeostatic temperature control in Drosophila
Umezaki, Y.; Hidalgo, S.; Nguyen, E.; Nguyen, T.; Suh, J.; Uchino, S. S.; Chiu, J. C.; Hamada, F. N.
10.1101/2022.09.30.510382 — neuroscience — Posted on 2023-11-22
1129 Impaired oxytocin signaling in the central amygdala in rats with chronic heart failure
Althammer, F.; Roy, R. K.; Kirchner, M. K.; Lira, E. C.; Schimmer, S.; Charlet, A.; Grinevich, V.; Sterm, J. E.
10.1101/2023.11.22.568271 — neuroscience — Posted on 2023-11-22
1131 Improvisation and Live Accompaniment Increase Motor Response and Reward During a Music Playing Task
Palumbo, A.; Groves, K.; Vidal, E. L. M.; Turry, A.; Codio, R.; Raghavan, P.; Schambra, H.; Voelbel, G.; Ripolles, P.
10.1101/2023.09.28.559982 — physiology — Posted on 2023-11-22
1132 Glutathione overproduction mediates lymphoma initiating cells survival and has a sex-dependent effect on lymphomagenesis
H.-Alcantara, A.; Kourani, O.; Marcos-Jimenez, A.; Martinez-Nunez, P.; Herranz-Martin, E.; Fuentes, P.; Toribio, M. L.; Munoz-Calleja, C.; Iglesias, T.; Campanero, M. R.
10.1101/2023.11.22.568023 — cancer biology — Posted on 2023-11-22
1133 Inflammatory Recruitment of Healthy Hematopoietic Stem and Progenitor Cells in the Acute Myeloid Leukemia Niche
Chen, D.-W.; Fan, J.-M.; Schrey, J. M.; Mitchell, D. V.; Jung, S. K.; Hurwitz, S. N.; Perez, E. B.; Muraro, M.; Carroll, M.; Taylor, D. M.; Kurre, P.
10.1101/2023.11.22.566265 — cancer biology — Posted on 2023-11-22
1137 Consistent individual positions within roosts in Spix's disc-winged bats
Giacomini, G.; Chaves-Ramirez, S.; Hernandez-Pinson, A.; Barrantes, J. P.; Chaverri, G.
10.1101/2022.11.04.515223 — ecology — Posted on 2023-11-22
1140 Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8
PEREZ, Y.; ALHOURANI, F.; PATOUILLARD, J.; Ribeyre, C.; Larroque, M.; BALDIN, V.; Lleres, D.; GRIMAUD, C.; JULIEN, E.
10.1101/2023.11.22.567520 — molecular biology — Posted on 2023-11-22
1141 Engineering luminopsins with improved coupling efficiencies
Slaviero, A.; Gorantla, N.; Simkins, J. W.; Crespo, E. L.; Ikefuama, E. C.; Tree, M. O.; Prakash, M.; Bjorefeldt, A.; Barnett, L. M.; Lambert, G. G.; Lipscombe, D.; Moore, C. I.; Shaner, N. C.; Hochgeschwender, U.
10.1101/2023.11.22.568342 — molecular biology — Posted on 2023-11-22
1142 Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes
Oguntuyo, K. Y.; Haas, G. D.; Azarm, K. D.; Stevens, C. S.; Brambilla, L.; Kowdle, S. S.; Avanzato, V. A.; Pryce, R.; Freiberg, A. N.; Bowden, T. A.; Lee, B.
10.1101/2023.11.22.568281 — molecular biology — Posted on 2023-11-22
1144 β-lactamase expression induces collateral sensitivity in Escherichia coli
Herencias, C.; Alvaro-Llorente, L.; Ramiro-Martinez, P.; Munoz-Cazalla, A.; DeLaFuente, J.; Castillo-Polo, J. A.; Canton, R.; San Millan, A.; Rodriguez-Beltran, J.
10.1101/2023.11.22.568265 — microbiology — Posted on 2023-11-22
1145 Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study
Srinivasan, V.; Bao, N. L. H.; Vinh, D. N.; Thanh Hoang Le, N.; Thu, D. D.; Quang, N. L.; Trieu, L. P. T.; Nhung, H. N.; Ha, V. T. N.; Thai, P. V. K.; Ha, D. T. M.; Lan, N. H.; Caws, M.; Thwaites, G. E.; Javid, B.; Thuong, N. T.
10.1101/2023.11.22.568240 — microbiology — Posted on 2023-11-22
1146 Transmission dynamics of MERS-CoV in a transgenic human DPP4 mouse model
van Doremalen, N.; Bushmaker, T.; Fischer, R.; Okumura, A.; Figueroa, D.; McMinn, R. J.; Letko, M. C.; Saturday, G.; Munster, V.
10.1101/2023.11.22.568286 — microbiology — Posted on 2023-11-22
1147 Synaptic strength dynamics at cortical synaptic pathways is encoded by vigilance states duration
Marchal, P.; Salin, P.; Missaire, M.; Rampon, M.; Carponcy, J.; Parmentier, R.; Poe, G.; Malleret, G.; Comte, J.-C.
10.1101/2023.11.22.567828 — neuroscience — Posted on 2023-11-22
1148 Antibody-based immunotherapy targeting FAM19A5 reverses synaptic loss and improves cognitive function in Alzheimer's disease.
Seong, J. Y.; Kim, H.-B.; Yoo, S.; Kwak, H.; Ma, S.-X.; Kim, R.; Lee, M.; Ha, N.; Pyo, S.; Kwon, S.-G.; Cho, E.-H.; Lee, S.-M.; Jang, J.; Kim, W.; Park, H.-C.; Baek, M.; Park, Y.; Park, J.-Y.; Park, J.-W.; Hwang, S. W.; Hwang, J.-I.
10.1101/2023.11.22.568357 — neuroscience — Posted on 2023-11-22
1150 dFLASH; dual FLuorescent transcription factor Activity Sensor for Histone integrated live-cell reporting and high-content screening
Allen, T. P.; Roennfeldt, A. E.; Reckdharajkumar, M.; Liu, M.; Quinn, R.; Russell, D. L.; Peet, D. J.; Whitelaw, M. L.; Bersten, D. C.
10.1101/2023.11.21.568191 — synthetic biology — Posted on 2023-11-22
1151 Adherent reformed islets: a long-term primary cell-based platform for exploring mouse and human islet biology.
Haq, N.; Toczyska, K.; Wilson, M.; Jacobs, M.; Lei, Y.; Zhoa, M.; Pearson, J.; Persaud, S.; Pullen, T.; Bewick, G. A.
10.1101/2023.11.22.568245 — physiology — Posted on 2023-11-22
1152 Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses
Kretsch, R. C.; Xu, L.; Zheludev, I. N.; Zhou, X.; Huang, R.; Nye, G.; Li, S.; Zhang, K.; Chiu, W.; Das, R.
10.1101/2023.11.22.567964 — biophysics — Posted on 2023-11-22
1153 Fast and accurate disulfide bridge detection
Heissel, S.; He, Y.; Jankevics, A.; Shi, Y.; Molina, H.; Viner, R.; Scheltema, R. A.
10.1101/2023.11.22.568205 — biochemistry — Posted on 2023-11-22
1162 The Ecosystem Integrity Index: a novel measure of terrestrial ecosystem integrity
Hill, S. L. L.; Harrison, M.; Maney, C.; Fajardo, J.; Harris, M.; Ash, N.; Bedford, J.; Danks, F.; Guaras, D.; Hughes, J.; Jones, M.; Mason, T.; Burgess, N. D.
10.1101/2022.08.21.504707 — ecology — Posted on 2023-11-22
1168 Cargo selective vesicle tethering: the structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23
Cattin-Ortola, J.; Kaufman, J. G. G.; Gillingham, A. K.; Wagstaff, J. L.; Peak-Chew, S.-Y.; Stevens, T. J.; Owen, D. J.; Munro, S.
10.1101/2023.11.22.568253 — cell biology — Posted on 2023-11-22
1169 Selective activation of intracellular β1AR using a spatially restricted antagonist
Liccardo, F.; Morstein, J.; Lin, T.-Y.; Pampel, J.; Shokat, K.; Irannejad, R.
10.1101/2023.11.22.568314 — cell biology — Posted on 2023-11-22
1170 METTL3 alters capping enzyme expression and its activity on ribosomal proteins
del Valle-Morales, D.; Romano, G.; Le, P.; Saviana, M.; Brown, R.; Micalo, L.; Li, H.; La Ferlita, A.; Nigita, G.; Nana-Sinkam, P.; Acunzo, M.
10.1101/2023.11.22.568301 — molecular biology — Posted on 2023-11-22
1171 Metabolic connections between folate and peptidoglycan pathways in Pseudomonas aeruginosa inform rational design of a dual-action inhibitor
Yaeger, L. N.; Sycantha, D.; Luong, P.; Shekarriz, S.; Goncalves, O.; Dobrin, A.; Ranieri, M. R.; Lamers, R. P.; Harvey, H.; diCenzo, G. C.; Surette, M. G.; Cote, J.-P.; Magolan, J.; Burrows, L. L.
10.1101/2023.11.22.568328 — microbiology — Posted on 2023-11-22
1173 Efficacy of an oral lipid nanocrystal (LNC) formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis
Gu, Y.; Gebremariam, T.; Alkhazraji, S.; Youssef, E.; El-Gamal, S.; Matkovits, T.; Cobb, J.; Mannino, R.; Ibrahim, A.
10.1101/2023.11.22.568278 — microbiology — Posted on 2023-11-22
1174 The effect of clinically relevant beta-lactam, aminoglycoside, and quinolone antibiotics on bacterial extracellular vesicle release from E. coli
TORABIAN, P.; Singh, N.; Crawford, J.; Gonzalez, G.; Burgado, N.; Videva, M.; Miller, A.; Perdue, J.; Dinu, M.; Pietropaoli, A.; Gaborski, T. R.; Michel, L. V.
10.1101/2023.11.22.568081 — microbiology — Posted on 2023-11-22
1175 Predicting phage-bacteria interactions at the strain level from genomes
Gaborieau, B.; Vaysset, H.; Tesson, F.; Charachon, I.; Dib, N.; Bernier, J.; Dequidt, T.; Georjon, H.; Clermont, O.; Hersen, P.; Debarbieux, L.; Ricard, J.-D.; Denamur, E.; Bernheim, A.
10.1101/2023.11.22.567924 — microbiology — Posted on 2023-11-22
1178 The unique Legionella longbeachae capsule favors intracellular replication and immune evasion
Schmidt, S.; Mondino, S.; Gomez-Valero, L.; Escoll, P.; Mascarenhas, D. P.; Goncalves, A.; Rusniok, C.; Sachse, M.; Moya-Nilges, M.; Fontaine, T.; Zamboni, D. S.; Buchrieser, C.
10.1101/2023.11.22.568341 — microbiology — Posted on 2023-11-22
1179 Community behaviors of bacteria in flow: Divergent roles for transport and collective morphology
Hallinen, K. M.; Bodine, S. P.; Stone, H. A.; Muir, T. W.; Wingreen, N. S.; Gitai, Z.
10.1101/2023.11.22.568348 — microbiology — Posted on 2023-11-22
1180 SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback
Coelho, C. H.; Bloom, N.; Ramirez, S. I.; Parikh, U. M.; Heaps, A.; Sieg, S. F.; Greninger, A.; Ritz, J.; Moser, C.; Eron, J. J.; Currier, J. S.; Klekotka, P.; Wohl, D. A.; Daar, E. S.; Li, J.; Hughes, M. D.; Chew, K. W.; Smith, D. M.; Crotty, S.; Accelerating COVID-19 Therapeutic Interventions and Vaccines: 2/A5401 (ACTIV-2/A5401) Study Team,
10.1101/2023.11.21.567575 — immunology — Posted on 2023-11-22
1181 Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates
Moliva, J. I.; Andrew, S. F.; Flynn, B. J.; Wagner, D. A.; Foulds, K. E.; Gagne, M.; Flebbe, D. R.; Lamb, E.; Provost, S.; Marquez, J.; Mychalowych, A.; Lorag, C.; Honeycutt, C. C.; Burnett, M. R.; McCormick, L.; Henry, A. R.; Godbole, S.; Davis-Gardner, M. E.; Minai, M.; Bok, K. W.; Nagata, B. M.; Todd, J.-P. M.; McCarthy, E.; Dodson, A.; Kouneski, K.; Cook, A.; Pessaint, L.; Van Ry, A.; Valentin, D.; Young, S.; Littman, Y.; Boon, A. C. M.; Suthar, M. S.; Lewis, M. G.; Andersen, H.; Alves, D. A.; Woodward, R.; Leuzzi, A.; Vitelli, A.; Colloca, S.; Folgori, A.; Raggiolli, A.; Capone, S.; Nason
10.1101/2023.11.22.567930 — immunology — Posted on 2023-11-22
1183 A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaques
Smith, A. A.; Su, H.; Wallach, J.; Liu, Y.; Maiello, P.; Borish, H. J.; Winchell, C.; Simonson, A. W.; Lin, P. L.; Rodgers, M.; Filmore, D. J.; Sakal, J.; Lin, K.; Schnappinger, D.; Ehrt, S.; Flynn, J. L.
10.1101/2023.11.22.568105 — immunology — Posted on 2023-11-22
1184 Integrating leaf gas exchange and chlorophyll fluorescence to reveal the long-term regulation of photosynthesis in situ
Oivukkamäki, J.; Aalto, J.; Pfündel, E. E.; Tian, M.; Zhang, C.; Grebe, S.; Salmon, Y.; Hölttä, T. S.; Porcar-Castell, A.
10.1101/2023.11.22.568237 — plant biology — Posted on 2023-11-22
1185 Green Algae CO2 capture is powered by alternative electron pathways of photosynthesis
Peltier, G.; Stoffel, C.; Findinier, J.; Madireddi, S. K.; Dao, O.; Morin, A.; Epting, V.; Grossman, A.; Li-Beisson, Y.; Burlacot, A.
10.1101/2023.08.08.552514 — plant biology — Posted on 2023-11-22
1186 Low-cost 3D printed lenses for brightfield and fluorescence microscopy
Christopher, J.; Rooney, L. M.; Donnachie, M.; Uttamchandani, D.; McConnell, G.; Bauer, R.
10.1101/2023.11.22.568227 — biophysics — Posted on 2023-11-22
1187 Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
Neelsen, L. C.; Riel, E. B.; Rinne, S.; Schmid, F.-R.; Juers, B. C.; Bedoya, M.; Langer, J. P.; Eymsh, B.; Kiper, A. K.; Cordeiro, S.; Decher, N.; Baukrowitz, T.; Schewe, M.
10.1101/2023.11.22.568211 — biophysics — Posted on 2023-11-22
1189 Printing, Characterising, and Assessing Transparent 3D Printed Lenses for Optical Imaging
Rooney, L. M.; Christopher, J.; Watson, B.; Susir Kumar, Y.; Copeland, L.; Walker, L. D.; Foylan, S.; Amos, W. B.; Bauer, R.; McConnell, G.
10.1101/2023.11.22.568002 — biophysics — Posted on 2023-11-22
1191 Boosting performance of generative diffusion model for molecular docking by training on artificial binding pockets
Voitsitskyi, T.; Bdzhola, V.; Stratiichuk, R.; Koleiev, I.; Ostrovsky, Z.; Vozniak, V.; Khropachov, I.; Henitsoi, P.; Popryho, L.; Zhytar, R.; Yesylevskyy, S. O.; Nafiev, A.; Starosyla, S.
10.1101/2023.11.22.568238 — bioinformatics — Posted on 2023-11-22
1193 Impact of electrodes design and insertion methods to surrounding cortical tissues from high-density arrays.
McNamara, I. N.; Wellman, S. M.; Li, L.; Eles, J. R.; Savya, S.; Sohal, H.; Angle, M.; Kozai, T. D. Y.
10.1101/2023.11.22.568119 — bioengineering — Posted on 2023-11-22
1194 Transwell-based microphysiological platform for high-resolution imaging of airway tissues
Kurmashev, A.; Boos, J. A.; Swart, L.; Laventie, B.-J.; Junne, T.; Suetterlin, R.; Jenal, U.; Hierlemann, A.
10.1101/2023.11.22.567838 — bioengineering — Posted on 2023-11-22
1195 Genome-Wide Exploration of the Opportunistic Providencia stuartii Unveils the Novel Genetic Interactions with the Virulence Gene of Diarrheal Pathogens
Hossain, M. U.; Hossain, M. S.; Rahman, A. B. Z. N.; Dey, S.; Chowdhury, Z. M.; Bhattacharjee, A.; Ahammad, I.; Aziz, M. A.; Hashem, A.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.11.22.568233 — genomics — Posted on 2023-11-22
1196 DNA methylation carries signatures of sublethal effects under thermal stress in loggerhead sea turtles
Yen, E. C.; Gilbert, J. D.; Balard, A.; Afonso, I. O.; Fairweather, K.; Newlands, D.; Lopes, A.; Correia, S. M.; Taxonera, A.; Rossiter, S. J.; Martin-Duran, J. M.; Eizaguirre, C.
10.1101/2023.11.22.568239 — genomics — Posted on 2023-11-22
1200 Mechanisms of transcriptional regulation in Anopheles gambiae revealed by allele specific expression
Dyer, N. A.; Lucas, E. R.; Nagi, S. C.; McDermott, D. P.; Brenas, J. H.; Miles, A.; Clarkson, C. S.; Mawejje, H. D.; Wilding, C. S.; Halfon, M. S.; Asma, H.; Heinz, E.; Donnelly, M. J.
10.1101/2023.11.22.568226 — genetics — Posted on 2023-11-22
1201 Intra and interspecific diversity in a tropical plant clade alter herbivory and ecosystem resilience
Grele, A.; Massad, T. J.; Uckele, K. A.; Dyer, L.; Antonini, Y.; Braga, L.; Forister, M. L.; Sulca, L.; Kato, M.; Lopez, H. G.; Nascimento, A. R.; Parchman, T.; Simbana, W. R.; Smilanich, A. M.; Stireman, J. O.; Tepe, E. J.; Walla, T.; Richards, L. A.
10.1101/2023.03.05.531210 — ecology — Posted on 2023-11-22
1202 Cadherins modulate the self-organizing potential of gastruloids
Mayran, A.; Kolly, D.; Lopez-Delisle, L.; Romaniuk, Y.; Leonardi, M.; Cossy, A.-C.; Lacroix, T.; Amandio, A.-R.; Osteil, P.; Duboule, D.
10.1101/2023.11.22.568291 — developmental biology — Posted on 2023-11-22
1204 Aging and freezing of active nematic dynamics of cancer-associated fibroblasts by fibronectin matrix remodeling
Jacques, C.; Ackermann, J.; Bell, S.; Hallopeau, C.; Perez-Gonzalez, C.; Balasubramaniam, L.; Trepat, X.; Ladoux, B.; Maitra, A.; Voituriez, R.; Matic Vignjevic, D.
10.1101/2023.11.22.568216 — cell biology — Posted on 2023-11-22
1207 Structural Basis for Mis18 Complex Assembly: Implications for Centromere Maintenance
Thamkachy, R.; Medina-Pritchard, B.; Park, S. H.; Chiodi, C. G.; Zou, J.; de la Torre-Barranco, M.; Shimanaka, K.; Abad, M. A.; Gallego Paramo, C.; Feederle, R.; Ruksenaite, E.; Heun, P.; Davies, O. R.; Rappsilber, J.; Schneidman-Duhovny, D.; Cho, U.-S.; Jeyaprakash, A. A.
10.1101/2021.11.08.466737 — cell biology — Posted on 2023-11-22
1208 In the murine and bovine maternal mammary gland signal transducer and activator of transcription 3 is activated in clusters of epithelial cells around the day of birth
Hardwick, L. J. A.; Davies, B. P.; Pensa, S.; Burge-Rogers, M.; Davies, C.; Figueiredo Baptista, A.; Knott, R.; McCrone, I.; Po, E.; Strugnell, B. W.; Waine, K.; Wood, P.; Khaled, W. T.; Summers, H. D.; Rees, P.; Wills, J. W.; Hughes, K.
10.1101/2023.11.22.568246 — cell biology — Posted on 2023-11-22
1209 Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease
Polonsky, M.; Gerhardt, L. M. S.; Yun, J.; Koppitch, K.; Colon, K.; Amrhein, H.; Zheng, S.; Yuan, G.-C.; Thomson, M.; Cai, L.; McMahon, A. P.
10.1101/2023.11.22.568217 — molecular biology — Posted on 2023-11-22
1211 Mixed Waste Contamination Selects for a Mobile Genetic Element Population Enriched in Multiple Heavy Metal Resistance Genes
Goff, J. L.; Lui, L. M.; Nielsen, T. N.; Poole, F. L.; Smith, H. J.; Walker, K. F.; Hazen, T. C.; Fields, M. W.; Arkin, A. P.; Adams, M. W. W.
10.1101/2023.11.17.566018 — microbiology — Posted on 2023-11-22
1212 Mice Models to Bioinformatics Methods Led to the Discovery of Antidiabetic Compounds in the F. racemosa Plant Extracts
Hossain, M. U.; Rahman, A. B. Z. N.; Hossain, M. S.; Dey, S.; Chowdhury, Z. M.; Bhattacharjee, A.; Ahammad, I.; Hasan, M. K.; Ahmed, I.; Hosen, M. B.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.11.22.568234 — microbiology — Posted on 2023-11-22
1213 Freezing responses during prolonged threat memory retrieval reflect trait-like anxiety endophenotypes in female and male inbred mice
Kovlyagina, I.; Wierczeiko, A.; Todorov, H.; Jacobi, E.; Tevosian, M.; von Engelhardt, J.; Gerber, S.; Lutz, B.
10.1101/2023.11.22.568236 — neuroscience — Posted on 2023-11-22
1214 Study design features that improve effect sizes in cross-sectional and longitudinal brain-wide association studies
Kang, K.; Seidlitz, J.; Bethlehem, R. A. I.; Xiong, J.; Jones, M. T.; Mehta, K. P.; Keller, A.; Tao, R.; Randolph, A.; Larsen, B.; Tervo-Clemmens, B.; Feczko, E. J.; Miranda Dominguez, O.; Nelson, S.; Lifespan Brain Chart Consortium, ; 3R-BRAIN, ; AIBL, ; Alzheimer's Disease Neuroimaging Initiative, ; Alzheimer's Disease Repository Without Borders Investigators, ; CALM Team, ; CCNP, ; COBRE, ; cVEDA, ; Harvard Aging Brain Study, ; IMAGEN, ; POND, ; The PREVENT-AD Research Group, ; Schildcrout, J.; Fair, D.; Satterthwaite, T. D.; Alexander-Bloch, A.; Vandekar, S.
10.1101/2023.05.29.542742 — neuroscience — Posted on 2023-11-22
1216 Revisiting Reddy: A DLBCL Do-over
Dreval, K.; Cruz, M.; Liuta, N.; Mirhosseini, H. L.; Brown, C.; Morin, R. D.; GAMBL Consortium,
10.1101/2023.11.21.567983 — genomics — Posted on 2023-11-22
1222 Stratification of human gut microbiomes by succinotype is associated with inflammatory bowel disease status
Anthamatten, L.; von Bieberstein, P. R.; Menzi, C.; Zuend, J. N.; Lacroix, C.; de Wouters, T.; Leventhal, G. E.
10.1101/2023.11.21.568118 — microbiology — Posted on 2023-11-22
1223 A therapeutic hepatitis B mRNA vaccine with strong immunogenicity and persistent virological suppression
Zhao, H.; Shao, X.; Yu, Y.; Huang, L.; Amor, N. P.; Guo, K.; Weng, C.; Zhao, W.; Yang, A.; Hu, J.; Yang, H.; Liu, Z.; Han, Q.; Shi, L.; Sun, S.; Zhang, J.; Yang, Y.; Lin, A.
10.1101/2022.11.18.517095 — immunology — Posted on 2023-11-22
1224 Unraveling the Power of NAP-CNB's Machine Learning-enhanced Tumor Neoantigen Prediction
Mendez-Perez, A.; Acosta-Moreno, A. M.; Wert-Carvajal, C.; Ballesteros-Cuartero, P.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Alemany, R.; Sorzano, C. O. S.; Munoz-Barrutia, A.; Veiga, E.
10.1101/2023.11.22.568042 — immunology — Posted on 2023-11-22
1226 Age-related differences in electrophysiological correlates of visuospatial reorientation
Naveilhan, C.; Delaux, A.; Durteste, M.; Lebrun, J.; Zory, R.; Arleo, A.; Ramanoel, S.
10.1101/2023.11.22.568209 — neuroscience — Posted on 2023-11-22
1227 Neural effects of TMS trains on the human prefrontal cortex
Ross, J. M.; Cline, C. C.; Sarkar, M.; Truong, J.; Keller, C. J.
10.1101/2023.01.30.526374 — neuroscience — Posted on 2023-11-22
1228 Can Colpoda travel across oceans? Salinity tolerance of resting cysts may enable global dispersal of the species.
Saito, R.; Yamanobe, H.; Yabuki, K.; Suzuki, T.; Saito, T.; Hakozaki, S.; Wanner, M.; Koizumi, R.; Sakai, T.; Maribet, G.; Tanaka, T.; Ono, A.; Nguyen, H. T.; Saito, Y.; Aoyama, T.; Kojima, K.; Suizu, F.; Watanabe, K.; Sogame, Y.
10.1101/2023.11.22.568208 — zoology — Posted on 2023-11-22
1229 THER: Integrative Web Tool for Tumor Hypoxia Exploration and Research
Zhang, Y.; Lin, A.; Yang, H.; Liu, Z.; Cheng, Q.; Zhang, J.; Luo, P.
10.1101/2023.11.21.568188 — cancer biology — Posted on 2023-11-22
1233 Engineering mice for female-biased progeny without impacting genetic integrity and litter size
Yosef, I.; Mahata, T.; Chen, Y.; Bar-Joseph, H.; Shalgi, R.; Munitz, A.; Gerlic, M.; Qimron, U.
10.1101/2023.11.21.568055 — bioengineering — Posted on 2023-11-22
1235 Polyglucosan body density in the aged mouse hippocampus is controlled by a novel modifier locus on chromosome 1
Gomez-Pascual, A.; Glikman, D. M.; Ng, H. X.; Tomkins, J. E.; Lu, L.; Xu, Y.; Ashbrook, D. G.; Kaczorowski, C.; Kempermann, G.; Killmar, J.; Mozhui, K.; Aebersold, R.; Williams, E. G.; Williams, R. W.; Overall, R. W.; Jucker, M.; de Bakker, D. E. M.
10.1101/2023.11.22.567373 — genetics — Posted on 2023-11-22
1236 Phenology across scales: an intercontinental analysis of leaf-out dates in temperate deciduous tree communities
Delpierre, N.; Garnier, S.; Treuil-Dussouet, H.; Hufkens, K.; Lin, J.; Beier, C.; Bell, M.; Berveiller, D.; Cuntz, M.; Curioni, G.; Dahlin, K.; Denham, S. O.; Desai, A. R.; Domec, J.-C.; Hart, K. M.; Ibrom, A.; Joetzjer, E.; King, J.; Klosterhalfen, A.; Koebsch, F.; McHale, P.; Morfin, A.; Munger, J. W.; Noormets, A.; Pilegaard, K.; Pohl, F.; Rebmann, C.; Richardson, A. D.; Rothstein, D.; Schwartz, M. D.; Wilkinson, M.; Soudani, K.
10.1101/2023.11.21.568089 — ecology — Posted on 2023-11-22
1237 Giant genes are rare but implicated in cell wall degradation by predatory bacteria
West-Roberts, J. A.; Valentin Alvarado, L. E.; Mullen, S.; Sachdeva, R.; Smith, J.; Hug, L. A.; Gregoire, D.; Liu, W.; Lin, T.-Y.; Husain, G.; Amano, Y.; Ly, L.; Banfield, J.
10.1101/2023.11.21.568195 — microbiology — Posted on 2023-11-22
1239 Butterfly wing iridescence is regulated by araucan, a direct target of optix and spalt
Chatterjee, M.; Siegel, K. J.; Loh, L. S.; McDonald, J. M. C.; Reed, R. D.
10.1101/2023.11.21.568172 — genetics — Posted on 2023-11-22
1240 Versatile toolkit for highly-efficient and scarless overexpression of circular RNAs
Stringer, B. W.; Gabryelska, M.; Marri, S.; Clark, L.; Lin, H.; Gantley, L.; Liu, R.; Wilusz, J. E.; Conn, V. M.; Conn, S. J.
10.1101/2023.11.21.568171 — molecular biology — Posted on 2023-11-22
1243 Hepatitis C virus cell culture adaptive mutations enhance cell culture propagation by multiple mechanisms but boost antiviral responses in primary human hepatocytes
Frericks, N.; Brown, R. J. P.; Reinecke, B. M.; Herrmann, M.; Brueggemann, Y.; Todt, D.; Miskey, C.; Vondran, F.; Steinmann, E.; Pietschmann, T.; Sheldon, J. A.
10.1101/2023.11.22.568224 — molecular biology — Posted on 2023-11-22
1246 A Potent Kalihinol Analogue Disrupts Apicoplast Function and Vesicular Trafficking in P. falciparum Malaria.
Chahine, Z. M.; Abel, S.; Hollin, T.; Chung, J. H.; Barnes, G. L.; Daub, M. E.; Renard, I.; Choi, J. Y.; Vydyam, P.; Chattopadhyay Pal, A.; Argomaniz, M.; Banks, C.; kirkwood, J.; Saraf, A.; Camino Diaz, I.; Castaneda-Casado, P.; Cuevas-Martin, M.; De Mercado-Arnanz, J.; Fernandez Alvaro, E.; Garcia-Perez, A.; Ibarz-Ferrer, N.; Viera-Morilla, S.; Prudhomme, J.; Joyner, C. J.; Bei, A.; Florens, L.; Ben Mamoun, C.; Vanderwal, C.; Le Roch, K. G.
10.1101/2023.11.21.568162 — microbiology — Posted on 2023-11-22
1247 Beyond the Colony-Forming-Unit: Rapid Bacterial Evaluation in Osteomyelitis
Sun, Q.; Huynh, K.; Muratovic, D.; Gunn, N. J.; Zelmer, A. R.; Solomon, L. B.; Atkins, G. J.; Yang, D.
10.1101/2023.11.21.568051 — microbiology — Posted on 2023-11-22
1248 SARS-CoV-2 infects neurons, astrocytes, choroid plexus epithelial cells and pericytes of the human central nervous system
Haverty, R.; McCormack, J.; Evans, C.; Purves, K.; O'Reilly, S.; Gautier, V. W.; Rochfort, K.; Fabre, A.; Fletcher, N.
10.1101/2023.11.21.568132 — microbiology — Posted on 2023-11-22
1251 Modulation of Biophysical Properties of Nucleocapsid Protein in the Mutant Spectrum of SARS-CoV-2
Nguyen, A.; Zhao, H.; Myagmarsuren, D.; Srinivasan, S.; Wu, D.; Chen, J.; Piszczek, G.; Schuck, P.
10.1101/2023.11.21.568093 — biophysics — Posted on 2023-11-22
1253 Asgard archaea modulate potential methanogenesis substrates in wetland soil
Valentin-Alvarado, L. E.; Appler, K. E.; De Anda, V.; Schoelmerich, M. C.; West-Roberts, J.; Kivenson, V.; Crits-Christoph, A.; Ly, L.; Sachdeva, R.; Savage, D. F.; Baker, B. J.; Banfield, J. F.
10.1101/2023.11.21.568159 — microbiology — Posted on 2023-11-22
1257 kallisto, bustools, and kb-python for quantifying bulk, single-cell, and single-nucleus RNA-seq
Sullivan, D. K.; Min, K. H.; Hjörleifsson, K. E.; Luebbert, L.; Holley, G.; Moses, L.; Gustafsson, J.; Bray, N. L.; Pimentel, H.; Booeshaghi, A. S.; Melsted, P.; Pachter, L.
10.1101/2023.11.21.568164 — bioinformatics — Posted on 2023-11-22
1264 Cooperativity and additivity in plant enhancers
Jores, T.; Tonnies, J.; Mueth, N. A.; Romanowski, A.; Fields, S.; Cuperus, J.; Queitsch, C.
10.1101/2023.11.21.568158 — plant biology — Posted on 2023-11-22
1266 A novel, wave-shaped profile of germline selection of pathogenic mtDNA mutations is discovered by bypassing a classical statistical bias.
Cote-LHeureux, A.; Fleischmann, Z.; Franco, M.; Chen, Z.; Khrapko, M.; Vyshedskiy, B.; Braverman, M.; Popadin, K.; Pickett, S.; Woods, D. C.; Tilly, J.; Turnbull, D.; Khrapko, K.
10.1101/2023.11.21.568140 — genomics — Posted on 2023-11-22
1267 One-pot Golden Gate Assembly of an avian infectious bronchitis virus reverse-genetics system
Bilotti, K.; Keep, S.; Sikkema, A. P.; Pryor, J. M.; Kirk, J. A.; Foldes, K.; Doyle, N.; Wu, G.; Dowgier, G.; Adeyemi, O.; Tabatabaei, S. K.; Lohman, G. J. S.; Bickerton, E.
10.1101/2023.11.21.566883 — genetics — Posted on 2023-11-22
1269 Exploring functional conservation in silico: a new machine learning approach to RNA-editing
Zawisza-Alvarez, M.; Penuela-Melero, J.; Vegas, E.; Reverter, F.; Garcia-Fernandez, J.; Herrera-Ubeda, C.
10.1101/2023.11.21.568001 — genetics — Posted on 2023-11-22
1274 A novel clinical metaproteomics workflow enables bioinformatic analysis of host-microbe dynamics in disease
Do, K.; Mehta, S.; Wagner, R.; Bhuming, D.; Rajczewski, A. T.; Skubitz, A. P. N.; Johnson, J. E.; Griffin, T.; Jagtap, P.
10.1101/2023.11.21.568121 — bioinformatics — Posted on 2023-11-22
1275 CPSign - Conformal Prediction for Cheminformatics Modeling
McShane, S. A.; Norinder, U.; Alvarsson, J.; Ahlberg, E.; Carlsson, L.; Spjuth, O.
10.1101/2023.11.21.568108 — bioinformatics — Posted on 2023-11-22
1279 Prospects and Challenges for Graphene Drums As Sensors Of Individual Bacteria
Roslon, I.; Japaridze, A.; Naarden, L.-V.; Smeets, L.; Dekker, C.; van Belkum, A.; Steeneken, P.; Alijani, F.
10.1101/2023.11.20.567863 — microbiology — Posted on 2023-11-22
1281 Effects of menopause and high fat diet on metabolic outcomes in a mouse model of Alzheimer's disease.
Abi-Ghanem, C.; Salinero, A. E.; Riccio, D.; Kelly, R. D.; Rybka, K. A.; Gannon, O. J.; Kordit, D.; Kyaw, N.-R.; Mansour, F.; Belanger, K. M.; Trasher, C. A.; Wang, M. K.; Groom, E.; Smith, R. M.; Brooks, H. L.; Robison, L. S.; Zuloaga, D. G.; Zuloaga, K. L.
10.1101/2023.11.21.568069 — neuroscience — Posted on 2023-11-22
1283 Neuroinfectiology of an atypical anthrax-causing pathogen in wild chimpanzees
Grasse, T.; Jager, C.; Kirilina, E.; Jaffe, J. E.; Carlier, P.; Pizarro, A.; Jauch, A.; Reimann, K.; Lipp, I.; Wittig, R. M.; Crockford, C.; Weiskopf, N.; Leendertz, F.; Morawski, M.
10.1101/2023.11.21.568053 — neuroscience — Posted on 2023-11-22
1286 Deep Learning Model Imputes Missing Stains in Multiplex Images
Shaban, M.; Lassoued, W.; Canubas, K.; Bailey, S.; Liu, Y.; Allen, C.; Strauss, J.; Gulley, J. L.; Jiang, S.; Mahmood, F.; Zaki, G.; Sater, H. A.
10.1101/2023.11.21.568088 — pathology — Posted on 2023-11-22
1287 Winging it: Unveiling how hummingbirds alter their flying kinematics during molt.
Diaz-Salazar, A. F.; Garzon-Agudelo, F.; Smiley, A.; Cadena, C. D.; Rico-Guevara, A.
10.1101/2023.11.21.568135 — biophysics — Posted on 2023-11-22
1294 Chemical cues from beetle larvae trigger proliferation and virulence of a plant pathogen
Cambon, M. C.; Thomas, G.; Caulfield, J. C.; Crampton, M.; Doonan, J. M.; Hussain, U.; Denman, S.; Vuts, J.; McDonald, J. E.
10.1101/2023.11.21.568124 — ecology — Posted on 2023-11-22
1295 A deep-learning-based screening platform in aging-relevant human motor neurons to identify therapeutic compounds for amyotrophic lateral sclerosis
Jalnapurkar, B.; Le, D.; Shainin, W.; Zarcone, R.; Bhatnagar, R.; Chin, J.; Corbin, C.; Curt, C.; Hodge, B.; Martinez, F.; Mikita, T.; Pipathsouk, A.; Rosen, J.; Rando, T. A.; Rodgers, J. T.; Linsley, J. W.
10.1101/2023.11.21.568079 — neuroscience — Posted on 2023-11-22
1298 Do NSm virulence factors in the Bunyavirales viral order originate from Gn gene duplication?
Lefebvre, V.; Leon Foun Lin, R.; Cole, L.; Cosset, F.-L.; Fogeron, M.-L.; Bockmann, A.
10.1101/2023.04.13.536692 — bioinformatics — Posted on 2023-11-22
1301 Pathogenic CD8 T cell responses are driven by neutrophil-mediated hypoxia in cutaneous leishmaniasis.
Fowler, E. A.; Farias Amorim, C.; Mostacada, K.; Yan, A.; Amorim Sacramento, L.; Stanco, R. A.; Hales, E. D. S.; Varkey, A.; Zong, W.; Wu, G. D.; de Oliveira, C. I.; Collins, P. L.; Novais, F. O.
10.1101/2023.10.18.562926 — immunology — Posted on 2023-11-22
1303 From Sequence to Significance: A Thorough Investigation of the Distinctive Genome Traits Uncovered in C. werkmanii strain NIB003
Hossain, M. U.; Tanvir, N. K.; Chowdhury, Z. M.; Rahman, A. B. Z. N.; Hossain, M. S.; Dey, S.; Bhattacharjee, A.; Ahmed, I.; Hashem, A.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.11.21.568014 — genomics — Posted on 2023-11-22
1304 Taste shaped the use of botanical drugs
Leonti, M.; Baker, J.; Staub, P.; Casu, L.; Hawkins, J.
10.1101/2023.07.18.549469 — evolutionary biology — Posted on 2023-11-21
1305 Aalbo1200: global genetic differentiation and variability of the mosquito Aedes albopictus
Crawford, J. E.; Beebe, N.; Bonizzoni, M.; Caputo, B.; Carter, B. H.; Chen, C.-H.; Cosme, L.; De Marco, C. M.; della Torre, A.; Estallo, E. L.; Guo, X.; Liu, W.-L.; Maringer, K.; Mains, J.; Maynard, A.; Mogi, M.; Livdahl, T.; Rose, N. H.; Scarafia, P. Y.; Severson, D.; Stein, M.; Surendran, S. N.; Tuno, N.; Wahid, I.; Wang, X.; Xu, J.; Yan, G.; Yee, D.; Armbruster, P. A.; Caccone, A.; White, B.
10.1101/2023.11.21.568070 — evolutionary biology — Posted on 2023-11-22
1306 Brain asymmetries from mid- to late life and hemispheric brain age
Korbmacher, M.; van der Meer, D.; Beck, D.; de Lange, A.-M. G.; Eikefjord, E.; Lundervold, A.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2023.08.21.554103 — neuroscience — Posted on 2023-11-22
1307 Hierarchical encoding of reward, effort and choice across the cortex and basal ganglia during cost-benefit decision making
Härmson, O.; Grennan, I.; Perry, B.; Toth, R.; McNamara, C. G.; Denison, T.; Cagnan, H.; Manohar, S. G.; Walton, M. E.; Sharott, A.
10.1101/2023.10.31.563750 — neuroscience — Posted on 2023-11-22
1309 OM2Seq: Learning retrieval embeddings for optical genome mapping
Nogin, Y.; Sapir, D.; Detinis Zur, T.; Weinberger, N.; Belinkov, Y.; Ebenstein, Y.; Shechtman, Y.
10.1101/2023.11.20.567868 — bioinformatics — Posted on 2023-11-22
1310 Plasma proteome signature of canine acute haemorrhagic diarrhoea syndrome (AHDS)
Huber, L.; Kuropka, B.; Doulidis, P. G.; Baszler, E.; Martin, L.; Rosu, A.; Kulmer, L.; Frizzo Ramos, C.; Rodriguez Rojas, A.; Burgener, I. A.
10.1101/2023.11.03.565505 — biochemistry — Posted on 2023-11-22
1313 Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations
Alqazzaz, M.; Luciani, G.; Vu, V.; Machado, R. M.; Szewczyk, M. M.; Adamson, E. C.; Cheon, S.; Arrowsmith, C.; Minden, M. D.; Barsyte-Lovejoy, D.
10.1101/2023.11.20.567858 — cancer biology — Posted on 2023-11-21
1314 The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer
Richtmann, S.; Marwitz, S.; Muley, T.; Koistinnen, H.; Christopoulos, P.; Thomas, M.; Kazdal, D. N.; Allgaeuer, M.; Winter, H.; Goldmann, T.; Meister, M.; Klingmueller, U.; Schneider, M. A.
10.1101/2023.03.02.530822 — cancer biology — Posted on 2023-11-22
1315 DFNA5-mediated pyroptosis is a driver for venetoclax and azacytidine synergy in myeloid leukemia
Mahesh, A. N.; Lai XIN-Yi, J.; Tng Jia Lin, M.; Lin, W.; Wan, J. C.; Yoon, J.; Chen, K.; Bhatt, S.
10.1101/2023.11.17.567421 — cancer biology — Posted on 2023-11-22
1320 Global metabolome changes induced by environmentally relevant conditions in a marine-sourced Penicillium restrictum
Le, V.-T.; BERTRAND, S.; Brandolini Bunlon, M.; Gentil, E.; Robiou du Pont, T.; Rabesaotra, V.; Wielgosz Collin, G.; Mossion, A.; Grovel, O.
10.1101/2023.09.06.556477 — microbiology — Posted on 2023-11-22
1322 A comprehensive data-driven model of cat primary visual cortex
Antolik, J.; Cagnol, R.; Rozsa, T.; Monier, C.; Fregnac, Y.; Davison, A. P.
10.1101/416156 — neuroscience — Posted on 2023-11-22
1328 Learning epistatic polygenic phenotypes with Boolean interactions
Behr, M.; Kumbier, K.; Cordova-Palomera, A.; Aguirre, M.; Ronen, O.; Ye, C.; Ashley, E.; Butte, A.; Arnaout, R.; Brown, J. B.; Preist, J.; Yu, B.
10.1101/2020.11.24.396846 — bioinformatics — Posted on 2023-11-22
1331 Effects of deafening on vocal production learning in the Egyptian fruit-bat
Elie, J. E.; Muroy, S. E.; Genzel, D.; Na, T.; Beyer, L. A.; Swiderski, D. L.; Raphael, Y.; Yartsev, M. M.
10.1101/2023.11.21.568126 — animal behavior and cognition — Posted on 2023-11-21
1332 Bayesian hierarchical modeling of size spectra
Wesner, J. S.; Pomeranz, J. P. F.; Junker, J. R.; Gjoni, V.
10.1101/2023.02.14.528491 — ecology — Posted on 2023-11-21
1333 Cohesin composition and dosage independently affect early development in zebrafish
Labudina, A.; Meier, M.; Gimenez, G.; Tatarakis, D.; Ketharnathan, S.; Mackie, B.; Schilling, T. F.; Antony, J.; Horsfield, J. A.
10.1101/2023.11.21.568176 — developmental biology — Posted on 2023-11-22
1336 GABAergic circuits reflect different requirements for emergent perception in postnatal mouse neocortex
Ghezzi, F.; Baruchin, L. J.; Ha, N. T.; Shah-Ostrowski, M. J.; Chama, A. G. C.; Stacey, J. A.; Butt, S. J. B.
10.1101/2023.11.21.568139 — neuroscience — Posted on 2023-11-21
1337 Distributed representations of innate behaviors in the hypothalamus do not predict specialized functional centers
Stagkourakis, S.; Spigolon, G.; Marks, M.; Feyder, M.; Kim, J.; Perona, P.; Pachitariu, M.; Anderson, D. J.
10.1101/2023.11.21.568163 — neuroscience — Posted on 2023-11-21
1338 A Cortico-Striatal Circuit for Sound-Triggered Prediction of Reward Timing
Suri, H.; Salgado-Puga, K.; Wang, Y.; Allen, N.; Lane, K.; Granroth, K.; Olivei, A.; Nass, N.; Rothschild, G.
10.1101/2023.11.21.568134 — neuroscience — Posted on 2023-11-21
1340 Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
Xiang, G.; He, X.; Giardine, B. M.; Isaac, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D. M.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.
10.1101/2023.04.02.535219 — genomics — Posted on 2023-11-21
1341 Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers
Xie, Y.; Ruan, F.; Li, Y.; Luo, M.; Zhang, C.; Chen, Z.; Xie, Z.; Weng, Z.; Chen, W.; Chen, W.; Fang, Y.; Sun, Y.; Guo, M.; Wang, J.; Xu, S.; Wang, H.; Tang, C.
10.1101/2022.04.21.489011 — genomics — Posted on 2023-11-21
1343 GetPrimers: a generalized PCR-based genetic targeting primer designer enabling easy and standardized targeted gene modification across multiple systems
Miao, Z.; Wang, H.; Tu, X.; Huang, Z.; Huang, S.; Zhang, X.; Wang, F.; Huang, Z.; Li, H.; Jiao, Y.; Gao, S.; Zhou, Z.; Shan, C.-M.; Li, J.; Yue, J.-X.
10.1101/2023.08.12.552711 — genetics — Posted on 2023-11-21
1344 Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.
Chen, J.; Landback, P.; Arsala, D.; Guzzetta, A.; Xia, S.; Atlas, J.; Dong, C.; Sosa, D.; Zhang, Y.; Cheng, J.; Shen, B.; Long, M.
10.1101/2023.11.14.567139 — evolutionary biology — Posted on 2023-11-21
1345 Cardiac glycosides protect wormseed wallflower (Erysimum cheiranthoides) against some, but not all, glucosinolate-adapted herbivores
Younkin, G. C.; Alani, M. L.; Paez Capador, A.; Fischer, H. D.; Mirzaei, M.; Hastings, A. P.; Agrawal, A.; Jander, G.
10.1101/2023.09.19.558517 — ecology — Posted on 2023-11-21
1346 Determinants of spring migration departure dates in a New World sparrow: weather variables reign supreme
Byrd, A. J.; Talbott, K. M.; Smiley, T. M.; Verrett, T. B.; Gross, M.; Hladik, M. L.; Ketterson, E. D.; Becker, D.
10.1101/2023.11.17.567563 — ecology — Posted on 2023-11-21
1351 Reactive Inhibitory Control Precedes Overt Stuttering Events
Orpella, J.; Flick, G.; Assaneo, F.; Pylkkanen, L.; Poeppel, D.; Jackson, E. S.
10.1101/2022.08.02.501857 — neuroscience — Posted on 2023-11-21
1353 Monosynaptic inputs to ventral tegmental area glutamate and GABA co-transmitting neurons
Prevost, E. D.; Phillips, A.; Lauridsen, K.; Enserro, G.; Rubinstein, B.; Alas, D.; McGovern, D. J.; Ly, A.; Banks, M.; McNulty, C. J.; Kim, Y. S.; Fenno, L. E.; Ramakrishnan, C. H.; Deisseroth, K.; Root, D. H.
10.1101/2023.04.06.535959 — neuroscience — Posted on 2023-11-21
1354 Evolution of aberrant brain-wide spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model
Vasilkovska, T.; Verschuuren, M.; Pustina, D.; van den Berg, M.; van Audekerke, J.; Pintelon, I.; Cachope, R.; De Vos, W. H.; Van der Linden, A.; Adhikari, M. H.; Verhoye, M.
10.1101/2023.11.20.567961 — neuroscience — Posted on 2023-11-21
1355 One-Hour Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer
Lancaster, N. M.; Sinitcyn, P.; Forny, P.; Peters-Clarke, T. M.; Fecher, C.; Smith, A. J.; Shishkova, E.; Arrey, T. N.; Pashkova, A.; Robinson, M. L.; Arp, N.; Fan, J.; Hansen, J.; Galmozzi, A.; Serrano, L. R.; Westphall, M. S.; Stewart, H.; Hock, C.; Damoc, E.; Pagliarini, D. J.; Zabrouskov, V.; Coon, J. J.
10.1101/2023.11.21.568149 — systems biology — Posted on 2023-11-21
1358 Alternative splicing controls teneurin-3 compact dimer formation for neuronalrecognition
Gogou, C.; Beugelink, J. W.; P. Frias, C.; Kresik, L.; Jaroszynska, N.; Drescher, U.; Janssen, B. J. C.; Hindges, R.; Meijer, D. H.
10.1101/2023.10.27.564434 — biochemistry — Posted on 2023-11-21
1359 The conserved genetic program of male germ cells uncovers ancient regulators ofhuman spermatogenesis
Brattig Correia, R.; Almeida, J. M.; Wyrwoll, M. J.; Julca, I.; Sobral, D.; Misra, C. S.; Di Persio, S.; Guilgur, L. G.; Schuppe, H.-C.; Silva, N.; Prudencio, P.; Novoa, A.; Leocadio, A. S.; Bom, J.; Laurentino, S.; Mallo, M.; Kliesch, S.; Mutwil, M.; Rocha, L. M.; Tüttelmann, F.; Becker, J. D.; Navarro-Costa, P.
10.1101/2022.03.02.482557 — developmental biology — Posted on 2023-11-21
1360 An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes
Yoon, L.; Botham, R. C.; Verhelle, A.; Wu, Y.; Cole, C.; Tan, E. P.; Massey, L. A.; Sanz-Martinez, P.; Chou, C. C.; Xu, J.; Elia, L. P.; Lee, K.; Labra, S. R.; Kline, G. M.; Xiao, Q.; Rhoades, D.; Cano-Franco, S.; Cuoco, C. A.; Ta, A.; Ren, W.; Hou, W. C.; Wulkop-Gil, C.; Ibrahim, L. H.; Nutsch, K.; Ko, Y.; Lederberg, O. L.; Peng, H.; Jiang, S.; Lipton, S. A.; Bollong, M. J.; Hansen, M.; Finkbeiner, S.; Finley, D.; Prado, M. A.; Petrassi, H. M.; Dikic, I.; Reggiori, F.; Garza, D.; Wiseman, R. L.; Powers, E. T.; Frydman, J.; Haggarty, S. J.; Johnson, K. A.; Silva, M. C.; Stolz, A.; Encalada, S.
10.1101/2022.09.29.509997 — cell biology — Posted on 2023-11-21
1362 Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
Chew, B. L. A.; Ngoh, A. Q.; Phoo, W. W.; Chan, W. K. K.; Zheng, S.; Tulsian, N. K.; Lim, S. S.; Weng, M. J. G.; Watanabe, S.; Choy, M. M.; Low, G. H. J.; Ooi, E. E.; Ruedl, C.; SOBOTA, R. M.; Vasudevan, S. G.; Luo, D.
10.1101/2022.04.06.487425 — microbiology — Posted on 2023-11-21
1363 Neuroinflammation induces nerve growth factor dependent nociceptor sensitisation in a neonatal rodent model of platinum-based chemotherapy induced neuropathic pain
Da Vitoria Lobo, M.; Hardowar, L.; Valentine, T.; Tomblin, L.; Guest, C.; Sharma, D.; Elphick-Ross, J.; Paul-Clark, M.; Hulse, R. P.
10.1101/2023.09.21.558866 — neuroscience — Posted on 2023-11-21
1364 Dynamic refinement of behavioural structure mediates dopamine-dependent credit assignment
Tang, J. C. Y.; Paixao, V.; Carvalho, F.; Silva, A.; Klaus, A.; Alves da Silva, J.; Costa, R. M.
10.1101/2022.09.22.507905 — neuroscience — Posted on 2023-11-21
1368 Oxygen isotopes in orangutan teeth reveal recent and ancient climate variation
Smith, T. M.; Arora, M.; Austin, C.; Avila, J. N.; Duval, M.; Lim, T. T.; Piper, P.; Vaiglova, P.; Vos, J. d.; Williams, I. S.; Zhao, J.-x.; Green, D. R.
10.1101/2023.07.18.549587 — paleontology — Posted on 2023-11-21
1369 Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA Damage Response inhibitors
Papp, O.; Jordan, V.; Hetey, S.; Balazs, R.; Bartha, A.; Ordasi, N. N.; Kamp, S.; Farkas, B.; Mettetal, J.; Dry, J. R.; Young, D.; Veres, D.; Sidders, B.; Bulusu, K. C.
10.1101/2023.11.20.567526 — cancer biology — Posted on 2023-11-21
1373 Fast and efficient root phenotyping via pose estimation
Berrigan, E. M.; Wang, L.; Carrillo, H.; Echegoyen, K.; Kappes, M.; Torres, J.; Ai-Perreira, A.; McCoy, E.; Shane, E.; Copeland, C. D.; Ragel, L.; Georgousakis, C.; Lee, S.; Reynolds, D.; Talgo, A.; Gonzalez, J.; Zhang, L.; Rajurkar, A. B.; Ruiz, M.; Daniels, E.; Maree, L.; Pariyar, S.; Busch, W.; Pereira, T. D.
10.1101/2023.11.20.567949 — plant biology — Posted on 2023-11-21
1375 Tibetan terrestrial and aquatic ecosystems collapsed with cryosphere loss inferred from sedimentary ancient metagenomics
Liu, S.; Stoof-Leichsenring, K.; Harms, L.; Schulte, L.; Mischke, S.; Kruse, S.; Zhang, C.; Herzschuh, U.
10.1101/2023.11.21.568092 — ecology — Posted on 2023-11-21
1376 Msc1 is a nuclear envelope protein that reinforces DNA repair in late mitosis.
Medina-Suarez, S.; Ayra-Plasencia, J.; Perez-Martinez, L.; Butter, F.; Machin, F.
10.1101/2023.11.21.568106 — molecular biology — Posted on 2023-11-21
1378 AvrSr27 is a zinc-bound effector with a modular structure important for immune recognition
Outram, M. A.; Chen, J.; Broderick, S.; Li, Z.; Aditya, S.; Tasneem, N.; Arndell, T.; Blundell, C.; Ericsson, D. J.; Figueroa, M.; Sperschneider, J.; Dodds, P.; Williams, S. J.
10.1101/2023.11.21.567997 — plant biology — Posted on 2023-11-21
1379 Ammonia inhibits antitumor activity of NK cells by decreasing mature perforin
Winiarska, M.; Domagala, J.; Grzywa, T. M.; Baranowska, I.; Kusowska, A.; Fidyt, K.; Marhelava, K.; Pilch, Z.; Graczyk-Jarzynka, A.; Picard, L.; Jastrzebski, K.; Granica, M.; Justyniarska, M.; Urlaub, D.; Bobrowicz, M.; Miaczynska, M.; Watzl, C.
10.1101/2023.11.20.567708 — cancer biology — Posted on 2023-11-21
1381 Single-molecule systems for detection and monitoring of plasma circulating nucleosomes and oncoproteins in Diffuse Midline Glioma
Erez, N.; Furth, N.; Fedyuk, V.; Wadden, J.; Aittaleb, R.; Schwark, K.; Niculcea, M.; Miclea, M.; Mody, R.; Franson, A.; Eze, A.; Nourmohammadi, N.; Nazarian, J.; Venneti, S.; Koschmann, C.; Shema, E.
10.1101/2023.11.21.568019 — cancer biology — Posted on 2023-11-21
1382 ERK Activation by BRAFV600E suppresses mesenchymal migration and tumorigenesis by inhibiting RAC1.
gadal, s.; Boyer, J. A.; Roy, S. F.; Outmezguine, N. A.; Sharma, M.; Li, H.; Fan, N.; Chan, E.; Romin, Y.; Barlas, A.; Chang, Q.; Pancholi, P.; Timaul, N. M.; Overholtzer, M.; Yaeger, R.; Todorova, K. M.; Stanchina, E. d.; Bosenberg, M.; Rosen, N.
10.1101/2023.11.21.568071 — cancer biology — Posted on 2023-11-21
1384 A DNA condensation code for linker histones
Watson, M.; Sabirova, D.; Hardy, M. C.; Pan, Y.; Yates, H.; Wright, C. J.; Chan, W. H.; Destan, E.; Stott, K.
10.1101/2023.11.20.567813 — biophysics — Posted on 2023-11-21
1385 iMab Antibody Binds Single-Stranded Cytosine-Rich Sequences and Unfolds DNA i-Motifs
Boissieras, J.; Bonnet, H.; Susanto, M. F.; Gomez, D.; Granzhan, A.; Defrancq, E.; Dejeu, J.
10.1101/2023.11.21.568054 — biophysics — Posted on 2023-11-21
1389 Transcriptional drift in aging cells: A global de-controller
Matsuzaki, T.; Weistuch, C.; de Graff, A.; Dill, K. A.; Balazsi, G.
10.1101/2023.11.21.568122 — biophysics — Posted on 2023-11-21
1395 Molecular Biomechanics of the TAS2R46 Bitter Taste Receptor through Network-based Investigation
Cannariato, M.; Fanunza, R.; Zizzi, E. A.; Miceli, M.; Di Benedetto, G.; Deriu, M. A.; Pallante, L.
10.1101/2023.11.21.568072 — bioengineering — Posted on 2023-11-21
1398 Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
Di Gioia, M.; Poli, V.; Tan, P.; Spreafico, R.; Chou, A.; Cuenca, A.; Gordts, P.; Pandolfi, L.; Meloni, F.; Witztum, J.; Chou, J.; Springstead, J.; Zanoni, I.
10.1101/2023.11.21.568047 — immunology — Posted on 2023-11-21
1400 A combination of physicochemical tropism and affinity moiety targeting of lipid nanoparticles enhances organ targeting
Zamora, M. E.; Omo-Lamai, S.; Patel, M. N.; Wu, J.; Arguiri, E.; Muzykantov, V.; Myerson, J. W.; Marcos-Contreras, O. A.; Brenner, J. S.
10.1101/2023.11.21.568061 — bioengineering — Posted on 2023-11-21
1404 Symbiosis modulates gene expression of symbionts, but not hosts, under thermal challenge
Aichelman, H. E.; Huzar, A. K.; Wuitchik, D. M.; Atherton, K. F.; Wright, R. M.; Dixon, G. B.; Schlatter, E.; Haftel, N.; Davies, S. W.
10.1101/2023.11.21.568130 — molecular biology — Posted on 2023-11-21
1406 Microplastics dysregulate innate immunity in the SARS-CoV-2 infected lung
Bishop, C. R.; Rawle, D. J.; Yan, K.; Tang, B.; Larcher, T.; Suhrbier, A.
10.1101/2023.11.19.567745 — microbiology — Posted on 2023-11-21
1407 Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86 lineages combining increased fitness and antibody evasion
Planas, D.; Staropoli, I.; Michel, V.; Lemoine, F.; Donati, F.; Prot, M.; Porrot, F.; Benhassine, F. G.; Jeyarajah, B.; Brisebarre, A.; Dehan, O.; Bolland, W.; Hubert, M.; Buchreiser, J.; Vanhoucke, T.; Rosenbaum, P.; Veyer, D.; Pere, H.; Lina, B.; Assant, S. T.; Hocqueloux, L.; Prazuck, T.; Loriere, E. S.; Schwartz, O.
10.1101/2023.11.20.567873 — microbiology — Posted on 2023-11-21
1408 Microbiome-based correction of nutrient profiles derived from self-reported dietary assessments
Wang, T.; Fu, Y.; Shuai, M.; Zheng, J.-S.; Zhu, L.; Sun, Q.; Hu, F. B.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.11.21.568102 — microbiology — Posted on 2023-11-21
1410 FrameDiPT: SE(3) Diffusion Model for Protein Structure Inpainting
Zhang, C.; Leach, A.; Makkink, T.; Arbesu, M.; Kadri, I.; Luo, D.; Mizrahi, L.; Krichen, S.; Lang, M.; Tovchigrechko, A.; Lopez Carranza, N.; Sahin, U.; Beguir, K.; Rooney, M.; Fu, Y.
10.1101/2023.11.21.568057 — immunology — Posted on 2023-11-21
1413 Enhancing Drug Delivery with Supramolecular Amphiphilic Macrocycle Nanoparticles: Selective Targeting of CDK4/6 Inhibitor Palbociclib to Melanoma
Attia, M. F.; Ogunnaike, E. A.; Pitz, M.; Elbaz, N. M.; Panda, D. K.; Alexander-Bryant, A.; Saha, S.; Whitehead, D. C.; Kabanov, A.
10.1101/2023.11.21.567974 — pharmacology and toxicology — Posted on 2023-11-21
1416 The Hippo kinase LATS1 controls CTCF chromatin occupancy and the hormonal response of three-dimensionally grown breast cancer cells
Cuellar, J. R.; Ferrari, R.; Sanz, R. T.; Santiago, M. V.; Nacht, A. S.; Le Dily, F.; Neguembor, M. V.; Andreo, D. C.; Malatesta, M.; Marti-Renom, M.; Beato, M.; Vicent, G. P.
10.1101/2023.11.20.566232 — genomics — Posted on 2023-11-21
1418 From Sequence to Significance: A Thorough Investigation of the Distinctive Genome Traits Uncovered in C. werkmanii strain NIB003
Hossain, M. U.; Tanvir, N. K.; Chowdhury, Z. M.; Rahman, A. N.; Hossain, M. S.; Dey, S.; Bhattacharjee, A.; Ahmed, I.; Hashem, A.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.11.21.568014 — genomics — Posted on 2023-11-21
1419 Cellular zinc status alters chromatin accessibility and binding of transcription factor TP53 to genomic sites
Damon, L. J.; Ocampo, D.; Sanford, L.; Jones, T.; Allen, M. A.; Dowell, R. D.; Palmer, A. E.
10.1101/2023.11.20.567954 — genomics — Posted on 2023-11-21
1420 Accounting for nuclear and mito genome in dairy cattle breeding - a simulation study
Mafra Fortuna, G.; Zumbach, B. J.; Johnsson, M.; Pocrnic, I.; Gorjanc, G.
10.1101/2023.11.20.567907 — genetics — Posted on 2023-11-21
1421 Phenotype projections accelerate biobank-scale GWAS
Zietz, M.; Gisladottir, U.; Brown, K. L.; Tatonetti, N. P.
10.1101/2023.11.20.567948 — genetics — Posted on 2023-11-21
1423 Identification of functional genes underlining growth in large yellow croaker
Wen, J.; Yue, Z.; Ji, J.; Yuan, Y.; Zhou, M.; Zhang, B.; Zhang, Y.; Ye, K.; Wang, Z.; Jiang, D.; Fang, M.
10.1101/2023.11.21.567991 — genetics — Posted on 2023-11-21
1425 Dollo parsimony overestimates ancestral gene content reconstructions
Morante, A. G.; Gueguen, L.; Natsidis, P.; Telford, M. J.; Richter, D. J.
10.1101/2023.11.20.567878 — evolutionary biology — Posted on 2023-11-21
1429 Functional and evolutionary integration of a fungal gene with a bacterial operon
Sun, L.; David, K. T.; Wolters, J. F.; Karlen, S. D.; Goncalves, C.; Opulente, D. A.; LaBella, A. L.; Groenewald, M.; Zhou, X.; Shen, X.-X.; Rokas, A.; Hittinger, C. T.
10.1101/2023.11.21.568075 — evolutionary biology — Posted on 2023-11-21
1433 Spatially explicit sampling frameworks to identify regions of increased mosquito abundance
Kemei, B.; Ochomo, E.; Ombok, M.; Midega, J.; Lucas, E. R.; Donnelly, M. J.; Sedda, L.; McDermott, D. P.
10.1101/2023.11.21.568008 — ecology — Posted on 2023-11-21
1434 Insights into Trypanosomiasis Transmission: Age, Infection Rates and Bloodmeal Analysis of Glossina fuscipes fuscipes in N.W. Uganda
Cunningham, L. J.; Esterhuizen, J.; Hargrove, J.; Lehane, M.; Lord, J.; Lingley, J.; Mangwiro, C. T. N.; Opiyo, M.; Torr, S.
10.1101/2023.11.21.568004 — ecology — Posted on 2023-11-21
1437 IDENTIFICATION OF PROMOTER ACTIVITY IN GENE-LESS CASSETTES FROM VIBRIONACEAE SUPERINTEGRONS
Blanco, P.; Hipolito, A.; Garcia-Pastor, L.; Trigo da Roza, F.; Toribio-Celestino, L.; Ortega, A. C.; Vergara, E.; San Millan, A.; Escudero, J. A.
10.1101/2023.11.21.568050 — microbiology — Posted on 2023-11-21
1439 Evolution of aberrant brain-wide spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model
Vasilkovska, T.; Verschuuren, M.; Pustina, D.; van den Berg, M.; van Audekerke, J.; Pintelon, I.; Cachope, R.; De Vos, W. H.; Van der Linden, A.; Adhikari, M. H.; Verhoye, M.
10.1101/2023.11.20.567961 — neuroscience — Posted on 2023-11-21
1442 Post-ischemic triiodothyronine treatment improves stroke outcome by stabilizing the blood-brain barrier
Ullrich, D.; Fuehrer-Sakel, D.; Heuer, H.; Mayerl, S.; Haupeltshofer, S.; Schmitt, L.-I.; Leo, M.; Hagenacker, T.; Kleinschnitz, C.; Langhauser, F.
10.1101/2023.11.21.568025 — neuroscience — Posted on 2023-11-21
1443 Partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy in mice lacking thyroid hormone receptor beta
Dore, R.; Sentis, S. C.; Johann, K.; Lopez-Alcantara, N.; Resch, J.; Moeller, L. C.; Fuehrer, D.; Obermayer-Wasserscheid, B.; Opitz, R.; Mittag, J.
10.1101/2023.11.21.567193 — physiology — Posted on 2023-11-21
1444 Role of ugt genes in detoxification and glycosylation of 1-hydroxy phenazine (1-HP) in Caenorhabditis elegans
Asif, M. Z.; Nocilla, K. A.; Ngo, L. T.; Shah, M. K.; Smadi, Y.; Hafeez, Z. A.; Parnes, M.; Manson, A.; Glushka, J.; Leach, F. E.; Edison, A. S.
10.1101/2023.11.21.568030 — biochemistry — Posted on 2023-11-21
1447 Lowering mutant huntingtin by small molecules relieves Huntington's disease symptoms and progression
Bahat, A.; Itzhaki, E.; Weiss, B.; Tolmasov, M.; Tsoory, M.; Kuperman, Y.; Brandis, A.; Shurrush, K.; Dikstein, R.
10.1101/2023.11.21.568060 — molecular biology — Posted on 2023-11-21
1449 Staphylococcus aureus skin colonization is mediated by SasG lectin variation
Mills, K. B.; Maciag, J. J.; Wang, C.; Crawford, J. A.; Enroth, T. J.; Keim, K. C.; Dufrene, Y. F.; Robinson, D. A.; Fey, P. D.; Herr, A. B.; Horswill, A. R.
10.1101/2023.11.20.567970 — microbiology — Posted on 2023-11-21
1450 CslA and GlxA from Streptomyces lividans form a functional cellulose synthase complex
Zhong, X.; Nicolardi, S.; Ouyang, R.; Wuhrer, M.; Du, C.; van Wezel, G. P.; Vijgenboom, E.; Briegel, A.; Claessen, D.
10.1101/2023.11.20.567928 — microbiology — Posted on 2023-11-21
1453 First isolate of Orientia tsutsugamushi from Vellore, South India
Kumaraswamy, J.; Kirubanandan, A.; Nagarajan, L. S.; Gunasekaran, K.; KPP, A.; Prakash, J. A. J.
10.1101/2023.11.21.568027 — microbiology — Posted on 2023-11-21
1454 Expression of the MSPDBL2 antigen in a discrete subset of Plasmodium falciparum schizonts is regulated by GDV1 but not linked to sexual commitment
Freville, A.; Stewart, L. B.; Tetteh, K. K.; Treeck, M.; Cortes, A.; Voss, T. S.; Tarr, S. J.; Baker, D. A.; Conway, D.
10.1101/2023.11.21.568010 — microbiology — Posted on 2023-11-21
1456 HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
Rouse, J. R.; Danner, R.; Wahhab, A.; Pereckas, M.; McClune, M.; Steere, A. C.; Strle, K.; Jutras, B. L.; Lochhead, R. B.
10.1101/2023.11.21.568066 — immunology — Posted on 2023-11-21
1462 Real-Time Structural Biology of DNA and DNA-Protein Complexes on an Optical Microscope
Szalai, A. M.; Ferrari, G.; Richter, L.; Hartmann, J.; Kesici, M.-Z.; Ji, B.; Koshic, K.; Jaeger, A.; Aksimentiev, A.; Tessmer, I.; Kaminska, I.; Vera, A. M.; Tinnefeld, P.
10.1101/2023.11.21.567962 — biophysics — Posted on 2023-11-21
1465 OM2Seq: Learning retrieval embeddings for optical genome mapping
Nogin, Y.; Sapir, D.; Detinis Zur, T.; Weinberger, N.; Belinkov, Y.; Ebenstein, Y.; Shechtman, Y.
10.1101/2023.11.20.567868 — bioinformatics — Posted on 2023-11-21
1466 SmCCNet 2.0: an Upgraded R package for Multi-omics Network Inference
Liu, W.; Vu, T.; Konigsberg, I. R.; Pratte, K. A.; Zhuang, Y.; Kechris, K. J.
10.1101/2023.11.20.567893 — bioinformatics — Posted on 2023-11-21
1468 Optimising machine learning prediction of minimum inhibitory concentrations in Klebsiella pneumoniae
Biffignandi, G. B.; Chindelevitch, L.; Corbella, M.; Feil, E. J.; Sassera, D.; Lees, J.
10.1101/2023.11.20.567835 — bioinformatics — Posted on 2023-11-21
1471 LightMHC: A Light Model for pMHC Structure Prediction with Graph Neural Networks
Delaunay, A. P.; Fu, Y.; Gorbushin, N.; McHardy, R.; Djermani, B. A.; Copoiu, L.; Rooney, M.; Lang, M.; Tovchigrechko, A.; Sahin, U.; Beguir, K.; Lopez Carranza, N.
10.1101/2023.11.21.568015 — bioinformatics — Posted on 2023-11-21
1472 Development and Characterization of a low intensity vibrational system for microgravity studies
Khan, O. M.; Gasperini, W.; Neccessary, C.; Jacobs, Z.; Perry, S.; Kuehl, P.; Nelson, K.; Gamble, P.; DeLeon, M.; Howard, S.; Zavala, A.; Farach-Carson, M. C.; Blaber, E. A.; Wu, D.; Satici, A.; Uzer, G.
10.1101/2023.11.20.567870 — bioengineering — Posted on 2023-11-21
1473 Polymer-mediated oligonucleotide delivery enables construction of barcoded 3D cultures for spatial single-cell analysis
King, J. J.; Mowla, A.; Kretzmann, J. A.; Norret, M.; Kadolsky, U. D.; Iqbal, M.; Saxena, A.; Mamsa, S. S. A.; Amos, S. E.; Choi, Y. S.; Kennedy, B. F.; Iyer, K. S.; Smith, N. M.; Evans, C. W.
10.1101/2023.11.20.567985 — bioengineering — Posted on 2023-11-21
1474 Identification and characterization of new structural scaffolds modulating the activity of Mycobacterium tuberculosis dihydroneopterin aldolase (FolB) in vitro
Falcao, V. C. d. A.; Czeczot, A. d. M.; Alam, M. M.; Park, K.-H. P.; Heo, J.; Woo, M.; Camini, A. M.; Timmers, L. F. S. M.; Shum, D.; Perello, M. A.; Basso, L. A.; Machado, P.; Bizarro, C. V.; Delorme, V. P.
10.1101/2023.11.21.567704 — biochemistry — Posted on 2023-11-21
1477 A global study of the geographic range size of epiphytes
Svahnstrom, V. J.; Lughadha, E. N.; Forest, F.; Leao, T. C. C.
10.1101/2023.11.20.567933 — ecology — Posted on 2023-11-21
1478 A Synthetic Cytotoxic T cell Platform for Rapidly Prototyping TCR Function
Sharma, G.; Round, J.; Teng, F.; Ali, Z.; May, C.; Yung, E.; Holt, R.
10.1101/2023.11.20.567960 — immunology — Posted on 2023-11-21
1479 Longitudinal analysis of innate immune system in infants with perinatal HIV infection until 18 months of age
Dinh, V.; de Armas, L.; Pallikkuth, S.; Pahwa, R.; Rinaldi, S.; Dang, C.; Kizhner, A.; Cotugno, N.; Palma, P.; Ismael, N.; Vaz, P.; Lain, M. G.; Pahwa, S.
10.1101/2023.11.21.568007 — immunology — Posted on 2023-11-21
1487 Roles for CEP170 in cilia function and dynein-2 assembly.
Weijman, J. F.; Vuolo, L.; Shak, C.; Pugnetti, A.; Mukhopadhyay, A. G.; Hodgson, L. R.; Heesom, K. J.; Roberts, A. J.; Stephens, D. J.
10.1101/2023.11.20.567836 — cell biology — Posted on 2023-11-21
1489 A mitochondria-regulated p53-CCF circuit integrates genome integrity with inflammation
Miller, K. N.; Li, B.; Pierce-Hoffman, H. R.; Lei, X.; Havas, A. P.; Patel, S.; Cano Macip, C.; Victorelli, S. G.; Woo, S.-H.; Lagnado, A. B.; Liu, T.; Dasgupta, N.; Lyu, J.; Altman, Y.; Porritt, R. A.; Garcia, G.; Mogler, C.; Dou, Z.; Chen, C.; Passos, J. F.; Adams, P. D.
10.1101/2023.11.20.567963 — cell biology — Posted on 2023-11-21
1490 Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line
Mortessagne, P.; Cartier, E.; Balia, M.; Fevre, M.; Corailler, F.; Herry, C.; Abrous, N.; Battefeld, A.; Pacary, E.
10.1101/2023.11.20.567945 — neuroscience — Posted on 2023-11-21
1494 Multiple focal pulvinar projection fields in the macaque cortex
Froesel, M.; Clavagnier, S.; Goudard, Q.; Zhu, Q.; Vanduffel, W.; Ben Hamed, S.
10.1101/2023.11.20.567885 — neuroscience — Posted on 2023-11-21
1495 Glucose-fed microbiota alters intestinal epithelium and increases susceptibility to bacterial pathogens
Kingsley, S. F.; Seo, Y.; Wood, A.; Wani, K. A.; Gonzalez, X.; Irazoqui, J. E.; Finkel, S. E.; Tissenbaum, H. A.
10.1101/2023.11.19.567723 — physiology — Posted on 2023-11-21
1497 Assessing Tumor Microenvironment Characteristics and Stratifying EPR with a Nanobubble Companion Nanoparticle via Contrast-Enhanced Ultrasound Imaging
Cooley, M. B.; Wegierak, D.; Perera, R.; Abenojar, E. C.; Nittayacharn, P. A.; Berg, F. M.; Kim, Y.; Kolios, M. C.; Exner, A. A.
10.1101/2023.11.20.567934 — bioengineering — Posted on 2023-11-21
1501 A novel highly divergent enteric calicivirus in a bovine calf, India
Kumar, N.; Kaushik, R.; Yadav, P.; Sircar, S.; Shete-Aich, A.; Singh, A.; Malik, Y. S.
10.1101/2023.11.20.567882 — microbiology — Posted on 2023-11-21
1509 Statistical Methods for Microrheology of Airway Mucus with Extreme Heterogeneity
Caughman, N.; Papanikolas, M.; Markovetz, M. R.; Freeman, R.; Hill, D. B.; Forest, M. G.; Lysy, M.
10.1101/2023.11.20.567244 — microbiology — Posted on 2023-11-21
1512 Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response
Bhagchandani, S.; Yang, L.; Maiorino, L.; Ben-Akiva, E.; Rodrigues, K. A.; Romanov, A.; Suh, H.; Aung, A.; Wu, S.; Wadhera, A.; Chakraborty, A. K.; Irvine, D. J.
10.1101/2023.11.20.563479 — immunology — Posted on 2023-11-21
1513 Chikungunya-virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans
Chang, J.; Agarwal, R.; Cortes, F. H.; Ha, C.; Villalpando, J.; Castillo, I.; Galvez, R. I.; Grifoni, A.; Sette, A.; Romero-Vivas, C. M.; Heise, M. T.; Lakshmanane, P.; Falconar, A. K.; Weiskopf, D.
10.1101/2023.11.20.567688 — immunology — Posted on 2023-11-21
1514 Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and airway dysfunction
Lopez, D. A.; Griffin, A.; Aguilar, L. M.; Deering-Rice, C.; Myers, E. J.; Warren, K. J.; Welner, R. S.; Beaudin, A. E.
10.1101/2023.11.20.567899 — immunology — Posted on 2023-11-21
1515 Vaccination of cattle with a virus-vectored vaccine against a major membrane protein of Mycobacterium a. subsp. paratuberculosis elicits CD8 cytotoxic T cells that kill intracellular bacteria
Mahmoud, A. h. A.; gabdellrazeq, G. s.; Franceschi, V.; Schneider, D. A.; Bannantine, J. P.; Fry, L. M.; Hullubei, V.; Demattis, G.; Park, K.-T.; Davis, W. C.; Donofrio, G.
10.1101/2023.11.20.567939 — immunology — Posted on 2023-11-21
1516 Peripheral gating of pain by glial endozepine
Li, X.; Prudente, A. S.; Prato, V.; Guo, X.; Han, H.; Jones, F.; Figoli, S.; Mullen, P.; Wang, Y.; Tonnello, R.; Lee, S. H.; Shah, S.; Maffei, B.; Berta, T.; Du, X.; Gamper, N.
10.1101/2023.11.20.567848 — neuroscience — Posted on 2023-11-21
1517 Excitatory neurons in stratum radiatum provide an alternative pathway for excitation flow that escapes perisomatic inhibition
Lebedeva, j.; Jappy, D. J.; Nasretdinov, A.; Vazetdinova, A.; Krut, V.; Sokolov, R.; Dobryakova, Y.; Eliava, M.; Grinevich, V.; Andrei, R.
10.1101/2023.11.20.567832 — neuroscience — Posted on 2023-11-21
1520 Plastic vasomotion entrainment
Sasaki, D.; Imai, K.; Ikoma, Y.; Matsui, K.
10.1101/2023.11.20.567853 — neuroscience — Posted on 2023-11-21
1521 Molecular regulation of retinal regeneration is context specific
Emmerich, K.; Hageter, J.; Hoang, T.; Lyu, P.; Sharrock, A. V.; Ceisel, A.; Thierer, J.; Chunawala, Z.; Nimmagadda, S.; Palazzo, I.; Matthews, F.; Zhang, L.; White, D. T.; Rodriguez, C.; Graziano, G.; Marcos, P.; May, A.; Mulligan, T.; Reibman, B.; Saxena, M. T.; Ackerley, D. F.; Qian, J.; Blackshaw, S.; Horstick, E.; Mumm, J. S.
10.1101/2023.11.20.567904 — neuroscience — Posted on 2023-11-21
1522 RNA sequencing demonstrates ex vivo neocortical transcriptomic changes induced by epileptiform activity in male and female mice
Vaughan, A. J.; McMeekin, L. J.; Hine, K.; Stubbs, I. W.; Codadu, N. K.; Cockell, S.; Hill, J. T.; Cowell, R.; Trevelyan, A. J.; Parrish, R. R.
10.1101/2023.11.20.567411 — neuroscience — Posted on 2023-11-21
1523 Cerebrospinal Fluid Flow Extends to Peripheral Nerves
Ligocki, A. P.; Vinson, A. V.; Yachnis, A. T.; Dunn, W. A.; Smith, D. E.; Scott, E. A.; Alvarez-Castanon, J. P.; Baez, D. E.; Frisone, O. G.; Brown, G.; Pessa, J. E.; Scott, E. W.
10.1101/2023.11.20.567884 — neuroscience — Posted on 2023-11-21
1526 Behavioral and neuropathological features of Alzheimer's disease are attenuated in 5xFAD mice treated with intranasal GHK peptide
Tucker, M.; Liao, G. Y.; Park, J. Y.; Rosenfeld, M.; Wezeman, J.; Mangalindan, R.; Ratner, D.; Darvas, M.; Ladiges, W. C.
10.1101/2023.11.20.567908 — neuroscience — Posted on 2023-11-21
1527 XCP-D: A Robust Pipeline for the post-processing of fMRI data
Mehta, K. P.; Salo, T.; Madison, T.; Adebimpe, A.; Bassett, D. S.; Bertolero, M.; Cieslak, M.; Covitz, S.; Houghton, A.; Keller, A. S.; Luo, A.; Miranda Dominguez, O.; Nelson, S.; Shafiei, G.; Shanmugan, S.; Shinohara, R.; Sydnor, V. J.; Feczko, E.; Fair, D. A.; Satterthwaite, T. D.
10.1101/2023.11.20.567926 — neuroscience — Posted on 2023-11-21
1531 High radiosensitivity in Norway spruce (Picea abies) is rendered by less comprehensive mobilisation of protection, repair and stress responses compared to the radiotolerant A. thaliana
Bhattacharjee, P.; Blagojevic, D.; Lee, Y.; Gillard, G. B.; Gronvold, L.; Hvidsten, T. R.; Sandve, S. R.; Lind, O. C.; Salbu, B.; Brede, D. A.; Olsen, J. E.
10.1101/2023.11.20.562501 — plant biology — Posted on 2023-11-21
1533 MaUGT79 confers drought tolerance by regulating scopolin biosynthesis in plants
Duan, Z.; Wu, F.; Yan, Q.; Wang, S.; Wang, Y.; Jones, C. S.; Zhou, P.; Zhang, C.; Zhang, J.
10.1101/2023.11.20.567956 — physiology — Posted on 2023-11-21
1536 Microeukaryote metabolism across the western North Atlantic Ocean revealed through autonomous underwater profiling
Cohen, N. R.; Krinos, A. I.; Kell, R. M.; Chmiel, R. J.; Moran, D. M.; McIlvin, M. R.; Lopez, P. Z.; Barth, A.; Stone, J.; Alanis, B. A.; Chan, E. W.; Breier, J. A.; Jakuba, M. V.; Johnson, R.; Alexander, H.; Saito, M. A.
10.1101/2023.11.20.567900 — ecology — Posted on 2023-11-21
1540 Plant-pollinator interactions in apple orchards from a production and conservation perspective
Mupepele, A.-C.; von Konigslow, V.; Bleile, A.-M.; Fornoff, F.; Frund, J.; Klein, A.-M.
10.1101/2023.11.20.567831 — ecology — Posted on 2023-11-21
1541 Whole-brain modelling of low-dimensional manifold modes reveals organising principle of brain dynamics
Sanz Perl, Y.; Geli, S.; Perez-Ordoyo, E.; Zonca, L.; Idesis, S.; Vohryzek, J.; Jirsa, V. K.; Kringelbach, M. L.; Tagliazucchi, E.; Deco, G.
10.1101/2023.11.20.567824 — neuroscience — Posted on 2023-11-21
1544 Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19
Aggarwal, A.; Singh, T. K.; Pham, M.; Godwin, M.; Chen, R.; McIntyre, T. M.; Chung, M. K.; Jennings, C.; Ali, M.; Park, H.; Englund, K.; Khorana, A. A.; Svensson, L.; Kapadia, S. R.; McCrae, K. R.; Cameron, S. J.
10.1101/2023.06.18.545507 — pharmacology and toxicology — Posted on 2023-11-21
1545 Phylogeny and disease links of a widespread and ancient gut phage lineage
de Jonge, P. A.; van den Born, B.-J. H.; Zwinderman, A. H.; Nieuwdorp, M.; Dutilh, B. E.; Herrema, H.
10.1101/2023.08.29.555303 — microbiology — Posted on 2023-11-21
1546 Single-cell somatic copy number variants in brain using different amplification methods and reference genomes
Kalef-Ezra, E.; Turan, Z. G.; Perez-Rodriguez, D.; Bomann, I.; Behera, S.; Morley, C.; Scholz, S. W.; Jaunmuktane, Z.; Demeulemeester, J.; Sedlazeck, F.; Proukakis, C.
10.1101/2023.08.07.552289 — neuroscience — Posted on 2023-11-21
1548 Whole-genome sequencing of major malaria vectors reveals the evolution of new insecticide resistance variants in a longitudinal study in Burkina Faso
Kientega, M.; Clarkson, C. S.; Traore, N.; Hui, T.-Y. J.; O'Loughlin, S. M.; Millogo, A.; Yao, F. A.; Epopa, P. S.; Belem, A. M. G.; Jon, B. H.; Miles, A.; Burt, A.; Diabate, A.
10.1101/2023.11.20.567800 — evolutionary biology — Posted on 2023-11-21
1549 Comprehensive Codon Usage Analysis Across Diverse Plant Lineages
Majeed, A.; Ul Rehman, W.; Kaur, A.; Das, S.; Joseph, J.; Singh, A.; Bhardwaj, P.
10.1101/2023.11.20.567812 — evolutionary biology — Posted on 2023-11-21
1555 Dopaminergic and Cholinergic Modulation of Human Cost-Benefit Decision Making
Erfanian Abdoust, M.; Frobose, M. I.; Schnitzler, A.; Schreivogel, E.; Jocham, G.
10.1101/2023.11.20.566558 — neuroscience — Posted on 2023-11-21
1557 E-cadherin is a structuring component of invadopodia in pancreatic cancer
Dobric, A.; Germain, S.; Silvy, F.; Bonier, R.; Audebert, S.; Camoin, L.; Dusetti, N. J.; Soubeyran, P.; Iovanna, J.; Rigot, V.; Andre, F.
10.1101/2020.10.09.332783 — cancer biology — Posted on 2023-11-21
1560 A workflow combining single-cell CRISPRi screening and a Sparse supervised autoencoder neural network to detect subtle transcriptomic perturbations induced by lncRNA Knock-Down
Truchi, M.; Lacoux, C.; Gille, C.; Fassy, J.; Magnone, V.; Lopez-Goncalvez, R.; Girard-Riboulleau, C.; Manosalva-Pena, I.; Gautier-Isola, M.; Lebrigand, K.; BARBRY, P.; Spicuglia, S.; Vassaux, G.; Rezzonico, R.; Barlaud, M.; Mari, B.
10.1101/2023.07.11.548494 — bioinformatics — Posted on 2023-11-21
1561 Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
Garcia-Cuesta, E. M.; Martinez, P.; Selvaraju, K.; Gomez Pozo, A. M.; D'Agostino, G.; Gardeta, S.; Quijada-Freire, A.; Blanco Gabella, P.; Roca, C.; Jimenez-Saiz, R.; Garcia-Rubia, A.; Soler Palacios, B.; Lucas, P.; Ayala-Bueno, R.; Santander Acerete, N.; carrasco, y.; Martinez, A.; Campillo, N. E.; Jensen, L. D.; Rodriguez Frade, J. M.; Santiago, C.; Mellado, M.
10.1101/2023.11.19.567737 — cell biology — Posted on 2023-11-21
1562 Control of Biofilm Formation by an Agrobacterium tumefaciens Pterin-Binding Periplasmic Protein Conserved Among Pathogenic Bacteria
Greenwich, J.; Eagan, J. L.; Feirer, N.; Boswinkle, K.; Minasov, G. A.; Shuvaloca, L.; Inniss, N. L.; Raghavaiah, J.; Ghosh, A.; Satchell, K. J. F.; Allen, K. D.; Fuqua, C.
10.1101/2023.11.18.567607 — microbiology — Posted on 2023-11-21
1563 Perceptual reorganisation from prior knowledge emerges late in childhood
Milne, G. A.; Lisi, M.; McLean, A.; Zheng, R.; Groen, I. I. A.; Dekker, T. M.
10.1101/2022.11.21.517321 — neuroscience — Posted on 2023-11-21
1572 MERLIN-DEFICIENT iPSCs AS AN IN VITRO MODEL SYSTEM FOR STUDIYNG NF2 PATHOGENESIS
Catasus, N.; Torres-Martin, M.; Negro, A.; Kuebler, B.; Rosas, I.; Casals, G.; Mazuelas, H.; Roca-Ribas, F.; Amilibia, E.; Aran, B.; Veiga, A.; Raya, A.; Gel Moreno, B.; Blanco, I.; Serra, E.; Carrio, M.; CASTELLANOS, E.
10.1101/2022.12.14.520389 — cell biology — Posted on 2023-11-21
1573 Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans
Kop, B. R.; Shamli Oghli, Y.; Grippe, T. C.; Nandi, T.; Lefkes, J.; Meijer, S. W.; Farboud, S.; Engels, M.; Hamani, M.; Null, M.; Radetz, A.; Hassan, U.; Darmani, G.; Chetverikov, A.; den Ouden, H. E. M.; Bergmann, T. O.; Chen, R.; Verhagen, L.
10.1101/2023.02.22.527901 — neuroscience — Posted on 2023-11-21
1576 Adaptive planning depth in human problem solving
Eluchans, M.; Lancia, G. L.; Maselli, A.; D'Alessandro, M.; Gordon, J.; Pezzulo, G.
10.1101/2023.05.02.539099 — neuroscience — Posted on 2023-11-21
1577 Global Pannexin 1-deletion increases tumor-infiltrating lymphocytes in the BRAF/Pten mouse melanoma model.
Sanchez-Pupo, R. E.; Finch, G.; Johnston, D. E.; Craig, H.; Abdo, R.; Barr, K. J.; Kerfoot, S. M.; Dagnino, L.; Penuela, S.
10.1101/2023.07.28.551021 — cancer biology — Posted on 2023-11-21
1580 Spatially-resolved transcriptomics of human dentate gyrus across postnatal lifespan reveals heterogeneity in markers for proliferation, extracellular matrix, and neuroinflammation
Ramnauth, A. D.; Tippani, M.; Divecha, H. R.; Papariello, A. R.; Miller, R. A.; Pattie, E. A.; Kleinman, J. E.; Maynard, K. R.; Collado-Torres, L.; Hyde, T. M.; Martinowich, K.; Hicks, S. C.; Page, S. C.
10.1101/2023.11.20.567883 — neuroscience — Posted on 2023-11-21
1583 16p11.2 Microduplication is Associated with Lobule-Specific Abnormalities in Cerebellar Structure and Function
Hayes, C.; Halverson, H.; Keeran, K.; Tison, K.; Jacobo, K.; Karki, A.; Herring, I.; Tunuguntla, S.; Pace, M.; Doan, B.; Wen, H.; Klomp, A.; Lauffer, M.; Gaine, M. E.; Parker, K.; Williams, A. J.
10.1101/2023.11.20.565320 — neuroscience — Posted on 2023-11-21
1584 Sub-chronic peripheral CB1R inhibition enhances cognitive performance and induces hippocampal synaptic plasticity changes in naive mice
Bergada-Martinez, A.; de los Reyes-Ramirez, L.; Martinez-Torres, S.; Martinez-Gallego, I.; Maldonado, R.; Rodriguez-Moreno, A.; Ozaita, A.
10.1101/2023.11.21.567995 — neuroscience — Posted on 2023-11-21
1585 Novel sterol binding domains in bacteria
Zhai, L.; Bonds, A.; Smith, C. A.; Oo, H.; Chou, J. C.-C.; Welander, P. V.; Dassama, L. M. K.
10.1101/2022.05.15.491920 — biochemistry — Posted on 2023-11-21
1586 A Framework for Designing Efficient Deep Learning-Based Genomic Basecallers
Singh, G.; Alser, M.; Denolf, K.; Firtina, C.; Khodamoradi, A.; Cavlak, M. B.; Corporaal, H.; Mutlu, O.
10.1101/2022.11.20.517297 — genomics — Posted on 2023-11-21
1587 Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.
Chen, J.; Landback, P.; Arsala, D.; Guzzetta, A.; Xia, S.; Atlas, J.; Dong, C.; Sosa, D.; Zhang, Y.; Cheng, J.; Shen, B.; Long, M.
10.1101/2023.11.14.567139 — evolutionary biology — Posted on 2023-11-21
1590 Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis
Watanuki, S.; Kobayashi, H.; Sugiura, Y.; Yamamoto, M.; Karigane, D.; Shiroshita, K.; Sorimachi, Y.; Fujita, S.; Morikawa, T.; Koide, S.; Oshima, M.; Nishiyama, A.; Murakami, K.; Miho, H.; Tamaki, S.; Yamamoto, T.; Yabushita, T.; Tanaka, Y.; Nagamatsu, G.; Honda, H.; Okamoto, S.; Goda, N.; Tamura, T.; Nakamura-Ishizu, A.; Suematsu, M.; Iwama, A.; Suda, T.; Takubo, K.
10.1101/2023.03.16.532898 — cell biology — Posted on 2023-11-21
1591 14-3-3 binding motif phosphorylation disrupts Hdac4 organized condensates to stimulate cardiacreprogramming
Liu, L.; Lei, I.; Tian, S.; Gao, W.; Guo, Y.; Li, Z.; Sabry, Z.; Tang, P.; Chen, E.; Wang, Z.
10.1101/2023.11.20.567913 — cell biology — Posted on 2023-11-21
1601 Astyanax mexicanus surface and cavefish chromosome-scale assemblies for trait variation discovery
Warren, W. C.; Carroll, R. A.; Haggerty, L.; Keene, A. C.; McGaugh, S. E.; Ogeh, D.; Rice, E. S.; Roback, E.; Rohner, N.; Martin, F.; X, M.
10.1101/2023.11.16.567450 — genomics — Posted on 2023-11-21
1602 Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation
Heimlich, J. B.; Bhat, P.; Parker, A. C.; Jenkins, M. T.; Vlasschaert, C.; Ulloa, J.; Potts, C. R.; Olson, S.; Silver, A. J.; Ahmad, A.; Sharber, B.; Brown, D.; Hu, N.; van Galen, P.; Savona, M. R.; Bick, A. G.; Ferrell, P. B.
10.1101/2022.12.01.518580 — genetics — Posted on 2023-11-21
1603 Evolution of E. coli in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevance
Unni, R.; Andreani, N. A.; Vallier, M.; Heinzmann, S.; Taubenheim, J.; Guggeis, M. A.; Tran, F.; Vogler, O.; Kuenzel, S.; Hövener, J.-B.; Rosenstiel, P.; Kaleta, C.; Dempfle, A.; Unterweger, D.; Baines, J. F.
10.1101/2023.08.16.553450 — evolutionary biology — Posted on 2023-11-20
1604 Modeling individual variability in habitat selection and movement using integrated step-selection analyses
Chatterjee, N.; Wolfson, D.; Kim, D.; Gomez, J. V.; Freeman, S.; Bacheler, N. M.; Shertzer, K.; Taylor, C.; Fieberg, J.
10.1101/2023.07.31.551213 — ecology — Posted on 2023-11-21
1605 CEP44 is required for maintaining centriole duplication and spindle integrity
Zhang, D.; Wei, W.; Zou, X.; Meng, H.; Li, F.; Yao, M.; Teng, J.; Huang, N.; Chen, J.
10.1101/2023.11.20.567852 — cell biology — Posted on 2023-11-20
1608 Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia
Weinberger, T.; Messerer, D.; Joppich, M.; Fischer, M.; Garcia, C.; Kumaraswami, K.; Wimmler, V.; Ablinger, S.; Raeuber, S.; Fang, J.; Liu, L.; Liu, W. H.; Winterhalter, J.; Lichti, J.; Tomas, L.; Esfandyari, D.; Percin, G.; Salamanca, S. M.; Hidalgo, A.; Waskow, C.; Engelhardt, S.; Todica, A.; Zimmer, R.; Pridans, C.; Gomez-Perdiguero, E.; Schulz, C.
10.1101/2023.05.08.539799 — immunology — Posted on 2023-11-21
1612 Where top-down meets bottom-up: Cell-type specific connectivity map of the whisker system
Rault, N.; Bergmans, T.; Delfstra, N.; Kleijnen, B. J.; Zeldenrust, F.; Celikel, T.
10.1101/2023.07.31.551377 — neuroscience — Posted on 2023-11-20
1617 Designer antisense circRNAGFP reduces GFP protein abundance in transgenic Arabidopsis protoplasts in a sequence-specific manner, independent of RNAi pathways
Hossain, M.; Pfafenroth, C.; Imani, J.; Secic, E.; Sede, A. R.; Galli, M.; Heinlein, M.; Bindereif, A.; Ladera, M.; Kogel, K.-H.
10.1101/2023.11.20.567890 — plant biology — Posted on 2023-11-20
1619 Flowtigs: safety in flow decompositions for assembly graphs
Sena, F.; Ingervo, E.; Khan, S.; Prjibelski, A.; Schmidt, S.; Tomescu, A. I.
10.1101/2023.11.17.567499 — bioinformatics — Posted on 2023-11-20
1620 Development of UHPLC MS/MS method for determination and quantification of endocannabinoids in cerebrospinal fluid.
Hooshmand, K.; Ismoilova, V.; Wretlind, A.; Simonsen, A. H.; Hasselbalch, S. G.; Legido-Quigley, C.
10.1101/2023.11.20.567867 — biochemistry — Posted on 2023-11-20
1621 Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4
Yuan, M.; Peng, L.; Huang, D.; Gavin, A.; Luan, F.; Tran, J.; Feng, Z.; Zhu, X.; Matteson, J.; Wilson, I. A.; Nemazee, D.
10.1101/2023.11.20.567917 — biochemistry — Posted on 2023-11-20
1626 Whole genome association testing in 333,100 individuals across three biobanks identifies rare non-coding single variant and genomic aggregate associations with height
Hawkes, G.; Beaumont, R. N.; Li, Z.; Mandla, R.; Li, X.; Albert, C. M.; Arnett, D. K.; Ashley-Koch, A. E.; Ashrani, A. A.; Barnes, K. C.; Boerwinkle, E.; Brody, J. A.; Carson, A. P.; Chami, N.; Chen, Y.-D. I.; Chung, M. K.; Curran, J. E.; Darbar, D.; Ellinor, P. T.; Fornage, M.; Gordeuk, V. R.; Guo, X.; He, J.; Hwu, C.-M.; Kalyani, R. R.; Kaplan, R.; Kardia, S. L. R.; Kooperberg, C.; Loos, R. J. F.; Lubitz, S. A.; Minster, R. L.; Mitchell, B. D.; Murabito, J. M.; Palmer, N. D.; Psaty, B. M.; Redline, S.; Shoemaker, M. B.; Silverman, E. K.; Telen, M. J.; Weiss, S. T.; Yanek, L. R.; Zhou, H.; NH
10.1101/2023.11.19.566520 — genetics — Posted on 2023-11-20
1629 Interspecific transfer of genetic information through polyploid bridges
Kauai, F.; Bafort, Q.; Mortier, F.; Van Montagu, M.; Bonte, D.; Van de Peer, Y.
10.1101/2023.11.20.567804 — evolutionary biology — Posted on 2023-11-20
1632 A murky ruling threatens the fate of millions of US wetlands
Simmons, B. A.; Beck, M. W.; Flaherty-Walia, K.; Lewis, J.; Sherwood, E. T.
10.1101/2023.11.14.567035 — ecology — Posted on 2023-11-20
1633 Antagonistic conflict between transposon-encoded introns and guide RNAs
Zedaveinyte, R.; Meers, C.; Le, H. C.; Mortman, E. E.; Tang, S.; Lampe, G. D.; Pesari, S. R.; Gelsinger, D. R.; Wiegand, T.; Sternberg, S. H.
10.1101/2023.11.20.567912 — molecular biology — Posted on 2023-11-20
1634 A C-terminal HaloTag Impairs AGO2 Function
Shah, K. M.; Crozier, A. F. F.; Assaraf, A. A.; Arya, M.; Ribeiro, P. B.; Plevin, M. J.; Sharp, T. V.
10.1101/2023.11.20.567203 — molecular biology — Posted on 2023-11-20
1637 The staphylococcal type VII secretion system impacts daptomycin sensitivity through controlling bacterial cell envelope integrity
Smith, V.; Chandrasekharan, G.; Watkins, K.; Maset, R. G.; Yap, J.; Perrier, S.; Tchoupa, A. K.; Unnikrishnan, M.
10.1101/2023.11.20.567842 — microbiology — Posted on 2023-11-20
1638 Preclinical Characterization of the Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine
Modjarrad, K.; Che, Y.; Chen, W.; Wu, H.; Cadima, C. I.; Muik, A.; Maddur, M. S.; Tompkins, K. R.; Martinez, L. T.; Cai, H.; Hong, M.; Mensah, S.; Cumbia, B.; Falcao, L.; Chang, J. S.; Fennell, K. F.; Hyunh, K.; McLellan, T. J.; Sahasrabudhe, P.; Chen, W.; Cerswell, M.; Garcia, M. A.; Li, S.; Sharma, R.; Li, W.; Dizon, K.; Duarte, S.; Gillett, F.; Smith, R.; Illenberger, D. M.; Sweeney, K. E.; Vogel, A. B.; Anderson, A. S.; Sahin, U.; Swanson, K.
10.1101/2023.11.17.567633 — immunology — Posted on 2023-11-20
1641 Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor
YANG, J.; Jablonowski, C. M.; Quarni, W.; Singh, S.; Tan, H.; Bostanthirige, D. H.; Jin, H.; Fang, J.; Chang, T.-C.; Finkelstein, D.; Cho, J.-H.; Hu, D.; Pagala, V.; Sakurada, S. M.; Pruett-Miller, S. M.; Wang, R.; Murphy, A.; Freeman, K.; Peng, J.; Davidoff, A.; Wu, G.
10.1101/2023.06.26.546606 — cancer biology — Posted on 2023-11-20
1642 Targeting pediatric High-Grade Gliomas with OAcGD2-CAR Vδ2 T cells
Thomas, P.; Veerasamy, M.; Devinat, M.; Guiet, E.; Ollier, J.; Paris, P.; Entz-Werle, N.; Gratas, C.; Clemenceau, B.; Birkle, S.; Paris, F.; Pecqueur, C.; Fougeray, S.
10.1101/2023.11.17.567375 — cancer biology — Posted on 2023-11-20
1647 A Foundation Model for Cell Segmentation
Israel, U.; Marks, M.; Dilip, R.; Li, Q.; Schwartz, M. S.; Pradhan, E.; Pao, E.; Li, S.; Pearson-Goulart, A.; Perona, P.; Gkioxari, G.; Barnowski, R.; Yue, Y.; Van Valen, D. A.
10.1101/2023.11.17.567630 — bioinformatics — Posted on 2023-11-20
1650 Mouse Genome Editing from Scratch
Popova, J.; Bets, V.; Omelina, E.; Boldyreva, L.; Kozhevnikova, E.
10.1101/2023.11.20.567793 — bioengineering — Posted on 2023-11-20
1654 Multi-Factor Coral Disease Risk Forecasting for Early Warning and Management
Caldwell, J. M.; Liu, G.; Geiger, E.; Heron, S. F.; Eakin, C. M.; De La Cour, J.; Greene, A.; Raymundo, L.; Dryden, J.; Schlaff, A.; Stella, J. S.; Kindinger, T. L.; Couch, C. S.; Fenner, D.; Hoot, W.; Manzello, D.; Donahue, M. J.
10.1101/2023.10.23.563632 — ecology — Posted on 2023-11-20
1657 Disentangling abiotic and biotic effects of treated wastewater on stream biofilm resistomes enables the discovery of a new planctomycete beta-lactamase
Attrah, M.; Schaerer, M. R.; Esposito, M.; Gionchetta, G.; Buergmann, H.; Lens, P.; Fenner, K.; van de Vossenberg, J.; Robinson, S. L.
10.1101/2023.11.20.567610 — microbiology — Posted on 2023-11-20
1658 The HtrA chaperone monitors sortase-assembled pilus biogenesis in Enterococcus faecalis
Yong, A. M. H.; Colomer Winter, C.; Chong, K. K. L.; Gao, I. H.; Matysik, A.; Chen, S. L.; Kline, K. A.
10.1101/2023.11.20.567783 — microbiology — Posted on 2023-11-20
1659 The Expression of HIV-1 Tat in Lactococcus lactis
Selvam, D.; Silva, A. D.; Gohil, Y.; Singh, J.; Panchapakesan, A.; Hanna, L. E.; Ranga, U.
10.1101/2023.11.20.567837 — microbiology — Posted on 2023-11-20
1661 Caspase-1 activates gasdermin A in non-mammals
Billman, Z. P.; Kovacs, S. B.; Wei, B.; Kang, K.; Cisse, O. H.; Miao, E. A.
10.1101/2023.09.28.559989 — immunology — Posted on 2023-11-20
1668 Distinct mobility patterns of BRCA2 molecules at DNA damage sites
Paul, M. W.; Aaron, J.; Wait, E.; van Genderen, R. M.; Tyagi, A.; Kabbech, H.; Smal, I.; Chew, T.-L.; Kanaar, R.; Wyman, C.
10.1101/2023.02.20.527475 — cell biology — Posted on 2023-11-20
1670 Detecting Protein-DNA Binding in Single Molecules using Antibody Guided Methylation
Thatavarty, A.; Sagy, N.; Erdos, M. R.; Lee, I.; Simpson, J. T.; Timp, W.; Collins, F. S.; Bar, D. Z.
10.1101/2023.11.20.567792 — molecular biology — Posted on 2023-11-20
1671 The intracellular growth of the vacuolar pathogen Legionella pneumophila is dependent on the acyl chain composition of host membranes
Wilkins, A.; Schwarz, B.; Torres-Escobar, A.; Castore, R.; Landry, L.; Latimer, B.; Bohrnsen, E.; Bosio, C. M.; Dragoi, A.-M.; Ivanov, S. S.
10.1101/2023.11.19.567753 — microbiology — Posted on 2023-11-20
1674 Differential expression of core metabolic functions in Candidatus Altiarchaeum inhabiting distinct subsurface ecosystems
Esser, S. P.; Turzynski, V.; Plewka, J.; Moore, C. J.; Banas, I.; Soares, A.; Lee, J.; Woyke, T.; Probst, A. J.
10.1101/2023.11.20.567779 — microbiology — Posted on 2023-11-20
1675 Mapping cortical excitability in the human dorsolateral prefrontal cortex
Gogulski, J.; Cline, C. C.; Ross, J. M.; Truong, J.; Sarkar, M.; Parmigiani, S.; Keller, C. J.
10.1101/2023.01.20.524867 — neuroscience — Posted on 2023-11-20
1676 Crossmodal Hierarchical Predictive Coding for Audiovisual Sequences in Human Brain
Huang, Y. T.; Wu, C.-T.; Fang, Y.-X. M.; Fu, C.-K.; Koike, S.; Chao, Z. C.
10.1101/2023.11.19.567767 — neuroscience — Posted on 2023-11-20
1677 Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice
Brito, D. V. C.; Kupke, J.; Sokolov, R.; Cambridge, S.; Both, M.; Bengtson, C. P.; Rozov, A.; Oliveira, A. M. M.
10.1101/2023.11.17.567527 — neuroscience — Posted on 2023-11-20
1678 All-optical reporting of inhibitory receptor driving force in the nervous system.
Selfe, J. S.; Steyn, T. J. S.; Shorer, E. F.; Burman, R. J.; Dusterwald, K. M.; Abdelfattah, A. S.; Schreiter, E. R.; Newey, S. E.; Akerman, C. J.; Raimondo, J. V.
10.1101/2023.08.30.555464 — neuroscience — Posted on 2023-11-20
1679 On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance and welfare in broiler chickens
Guilloteau, L. A.; Bertin, A.; Crochet, S.; Bagnard, C.; Hondelatte, A.; Ravon, L.; Schouler, C.; Germain, K.; Collin, A.
10.1101/2023.05.17.541117 — physiology — Posted on 2023-11-20
1680 The Endothelium Modulates the Prothrombotic Phenotype of Factor V Leiden: Evidence from an Ex Vivo Model
Schwarz, N.; Muller, J.; McRae, H. L.; Reda, S.; Pezeshkpoor, B.; Oldenburg, J.; Potzsch, B.; Ruhl, H.
10.1101/2023.11.15.567299 — pathology — Posted on 2023-11-20
1681 Lung inflammation is associated with lipid deposition
Potashnikova, D. M.; Tvorogova, A. V.; Saidova, A. A.; Sotnikova, T. N.; Arifulin, E. A.; Lipina, T. V.; Shirokova, O. M.; Melnikov, E. S.; Rodina, T. A.; Valyaeva, A. A.; Zharikova, A. A.; Zayratyants, G. O.; Zayratyants, O. V.; Sheval, E. V.; Margolis, L. B.; Vasilieva, E. Y.
10.1101/2022.12.30.522299 — pathology — Posted on 2023-11-20
1682 KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma
Castoldi, M.; Roy, S.; Lohr, C.; Pellegrino, R.; Vucur, M.; Singer, M. T.; Buettner, V.; Dille, M. A.; Heij, L. R.; Zender, L.; Neumann, U. P.; Longerich, T.; Roderburg, C.; Luedde, T.
10.1101/2023.11.20.565448 — cancer biology — Posted on 2023-11-20
1684 Phosphorylation in the Plasmodium falciparum proteome: A meta-analysis of publicly available data sets
Camacho, O.; Ramsbottom, K.; Prakash, A.; Sun, Z.; Perez Riverol, Y.; Bowler-Barnett, E.; Martin, M.; Fan, J.; Deutsch, E.; Vizcaino, J. A.; Jones, A. R.
10.1101/2023.11.20.567785 — bioinformatics — Posted on 2023-11-20
1693 Mitochondrial Sodium/Calcium Exchanger (NCLX) Regulates Basal and Starvation-Induced Autophagy Through Calcium Signaling
de Miranda Ramos, V.; Serna, J. D.; Vilas-Boas, E. A.; Cabral-Costa, J. V.; da Cunha, F. M.; Kataura, T.; Korolchuk, V. I.; Kowaltowski, A. J.
10.1101/2023.03.17.533187 — cell biology — Posted on 2023-11-20
1694 Exploratory mass cytometry analysis reveals immunophenotypes of cancer treatment-related pneumonitis
Yanagihara, T.; Hata, K.; Matsubara, K.; Kunimura, K.; Suzuki, K.; Tsubouchi, K.; Ikegame, S.; Baba, Y.; Fukui, Y.; Okamoto, I.
10.1101/2023.02.21.529383 — immunology — Posted on 2023-11-20
1697 Mapping Cerebellar Anatomical Heterogeneity in Mental and Neurological Illnesses
Kim, M.; Leonardsen, E.; Rutherford, S.; Selbaek, G.; Persson, K.; Steen, N. E.; Smeland, O. B.; Ueland, T.; Richard, G.; Beckmann, C.; Marquand, A. F.; For the Alzheimer's Disease Neuroimaging Initiative (ADNI), ; Andreassen, O.; Westlye, L. T.; Wolfers, T.; Moberget, T.
10.1101/2023.11.18.567647 — neuroscience — Posted on 2023-11-20
1698 Transitions in dynamical regime and neural mode underlie perceptual decision-making
Luo, T. Z.; Kim, T. D.; Gupta, D.; Bondy, A. G.; Kopec, C. D.; Elliott, V. A.; DePasquale, B.; Brody, C.
10.1101/2023.10.15.562427 — neuroscience — Posted on 2023-11-20
1700 Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria
Sandin Garcia, D.; Valle, J.; Gomez, J.; Comas, L.; Larrosa, M. N.; Gonzalez, J. J.; Jimenez, M. A.; Andreu, D.; Torrent, M.
10.1101/2023.10.19.563059 — systems biology — Posted on 2023-11-20
1701 Proteomic Features of Adolescents and Young Adults with Soft Tissue Tumours
Tam, Y. B.; Low, K.; PS, H.; Chadha, M.; Burns, J.; Wilding, C.; Arthur, A.; Chen, T.; Thway, K.; Sadanandam, A.; Jones, R.; Huang, P. H.
10.1101/2023.11.18.567667 — cancer biology — Posted on 2023-11-20
1704 SEGMENTATION OF DYNAMIC TOTAL-BODY -FDG PET IMAGES USING UNSUPERVISED CLUSTERING
Jaakkola, M. K.; Rantala, M.; Jalo, A.; Saari, T.; Hentila, J.; Helin, J. S.; Nissinen, T. A.; Eskola, O.; Rajander, J.; Virtanen, K. A.; Hannukainen, J. C.; Lopez-Picon, F.; Klen, R.
10.1101/2023.06.20.545535 — bioinformatics — Posted on 2023-11-20
1705 Extraction and quantification of lineage-tracing barcodes with NextClone and CloneDetective
Putri, G. H.; Pires, N.; Davidson, N. M.; Blyth, C.; AlKhafaji, A.; Goel, S.; Phipson, B.
10.1101/2023.11.19.567755 — bioinformatics — Posted on 2023-11-20
1708 The YTHDF1-3 proteins are bidirectionally influenced by the codon content of their mRNA targets
Moch, C.; Zou, L.; Pythoud, N.; Fillon, E.; Bourgeois, G.; Graille, M.; Carapito, C.; Chapat, C.
10.1101/2023.11.20.565808 — cell biology — Posted on 2023-11-20
1709 Collagen receptor GPVI-mediated platelet activation and pro-coagulant activity aggravates inflammation and aortic wall remodelling in abdominal aortic aneurysm
Feige, T.; Bosbach, A.; Krott, K. J.; Mulorz, J.; Chatterjee, M.; Ortscheid, J.; Krueger, E.; Krueger, I.; Ibing, W.; Grandoch, M.; Wagenhaeuser, M. U.; Schelzig, H.; Elvers, M.
10.1101/2023.11.20.567851 — cell biology — Posted on 2023-11-20
1712 Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1 transcription signature
Shen, D.; Vincent, A.; Udine, E.; Buhidma, Y.; Anoar, S.; Tsintzas, E.; Maeland, M.; Rademakers, R.; Isaacs, A.; Frigerio, C. S.; van Blitterswijk, M.; Lashley, T.; Niccoli, T.
10.1101/2023.11.20.567861 — neuroscience — Posted on 2023-11-20
1713 Beet taproot plasma membrane sugar transport revisited
Reyer, A.; Bazihizina, N.; Jaslan, J.; Scherzer, S.; Schäfer, N.; Jaslan, D.; Müller, T. D.; Pommerrenig, B.; Marten, I.; Hedrich, R.
10.1101/2021.09.21.461191 — plant biology — Posted on 2023-11-20
1715 Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket
Huang, C.-Y.; Metz, A.; Lange, R.; Artico, N.; Potot, C.; Hazemann, J.; Mueller, M.; Dos Santos, M.; Chambovey, A.; Ritz, D.; Eris, D.; Meyer, S.; Bourquin, G.; Sharpe, M. E.; Mac Sweeney, A.
10.1101/2023.11.15.567102 — biophysics — Posted on 2023-11-20
1716 Planar cell polarity is essential for the architectural patterning of the mammalian biliary tree.
Raab, M.; Christodoulou, E.; Krishnankutty, R.; Younger, N. T.; Gournopanos, K.; Von Kriegsheim, A.; Waddell, S. H.; Boulter, L.
10.1101/2023.11.20.567871 — developmental biology — Posted on 2023-11-20
1717 An integrated transcriptomic cell atlas of human endoderm-derived organoids
Xu, Q.; Halle, L.; Hediyeh-zadeh, S.; Kuijs, M.; Kilik, U.; Yu, Q.; Frum, T.; Adam, L.; Parikh, S.; Gander, M.; Kfuri-Rubens, R.; Klein, D.; He, Z.; Fleck, J. S.; Oost, K.; Kahnwald, M.; Barbiero, S.; Mitrofanova, O.; Maciag, G.; Jensen, K. B.; Lutolf, M.; Liberali, P.; Beumer, J.; Spence, J. R.; Treutlein, B.; Theis, F. J.; Camp, J. G.
10.1101/2023.11.20.567825 — cell biology — Posted on 2023-11-20
1718 Genomic and phenotypic stability of fusion-driven pediatric Ewing sarcoma cell lines
Kasan, M.; Siebenlist, J.; Sill, M.; Oellinger, R.; de Alava, E.; Surdez, D.; Dirksen, U.; Oehme, I.; Scotlandi, K.; Delattre, O.; Mueller-Nurasyid, M.; Rad, R.; Strauch, K.; Gruenewald, T. G. P.; Cidre-Aranaz, F.
10.1101/2023.11.20.567802 — cell biology — Posted on 2023-11-20
1721 A Foundation Model for Cell Segmentation
Israel, U.; Marks, M.; Dilip, R.; Li, Q.; Schwartz, M. S.; Pradhan, E.; Pao, E.; Li, S.; Pearson-Goulart, A.; Perona, P.; Gkioxari, G.; Barnowski, R.; Yue, Y.; Van Valen, D. A.
10.1101/2023.11.17.567630 — bioinformatics — Posted on 2023-11-20
1724 Insight into the gut virome in patients with multiple sclerosis
Bokoliya, S. C.; Russell, J. T.; Yuan, H.; Xia, Z.; Piccio, L.; Zhou, Y.
10.1101/2023.11.17.567435 — microbiology — Posted on 2023-11-20
1725 A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D2/3 receptor densities
Ricard, J. A.; Labache, L.; Segal, A.; Dhamala, E.; Cocuzza, C. V.; Jones, G.; Yip, S.; Chopra, S.; Holmes, A. J.
10.1101/2023.11.17.567591 — neuroscience — Posted on 2023-11-20
1726 Association with TFIIIC limits MYCN localization in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA Polymerase II
Vidal, R.; Leen, E.; Herold, S.; Müller, M.; Fleischhauer, D.; Schülein-Völk, C.; Papadopoulos, D.; Röschert, I.; Uhl, L.; Ade, C. P.; Gallant, P.; Bayliss, R.; Eilers, M.; Büchel, G.
10.1101/2023.11.18.567687 — molecular biology — Posted on 2023-11-20
1727 Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane
Gonzalez Lopez, A.; Larsson, D. S. D.; KIran Koripella, R.; Cain, B. N.; Garcia Chavez, M.; Hergenrother, P. J.; SANYAL, S.; Selmer, M.
10.1101/2023.11.17.567578 — molecular biology — Posted on 2023-11-20
1729 Tau alters global gene expression affecting chromatin in the early stages of Alzheimer's disease
Siano, G.; Varisco, M.; Terrigno, M.; Wang, C.; Groth, M.; Galas, M.-C.; Hoozemans, J. J. M.; Cellerino, A.; Cattaneo, A.; Di Primio, C.
10.1101/2023.11.17.567548 — neuroscience — Posted on 2023-11-20
1730 Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons
Lin, W.; Wall, J.; Li, G.; Newman, D.; Yang, Y.; VandeBerg, J.; Abney, M.; Olivier, M.; Gilad, Y.; Cox, L. A.
10.1101/2023.08.01.551489 — genomics — Posted on 2023-11-20
1736 Analysis of a shark reveals ancient, Wnt dependent, habenular asymmetries in jawed vertebrates
Lanoizelet, M.; Michel, L.; Lagadec, R.; Mayeur, H.; Guichard, L.; Logieux, V.; Severac, D.; Martin, K. J.; Klopp, C.; Marcellini, S.; Castillo, H.; Pollet, N.; Candal, E.; Debiais-Thibaud, M.; Boisvert, C.; Billoud, B.; Schubert, M.; Blader, P.; MAZAN, S.
10.1101/2023.10.17.562666 — developmental biology — Posted on 2023-11-20
1739 Alterations in type 2 dopamine receptors across neuropsychiatric conditions: A large-scale PET cohort
Malen, T.; Santavirta, S.; De Maeyer, S.; Tuisku, J.; Kaasinen, V.; Kankare, T.; Isojärvi, J.; Rinne, J.; Hietala, J.; Nuutila, P.; Nummenmaa, L.
10.1101/2023.06.05.543660 — neuroscience — Posted on 2023-11-19
1740 Fibrinogen and complement factor H: The two crucial markers of Parkinson's disease with cognitive impairment
Naskar, A.; Sachin, M.; Sengupta, S.; Bhadrachallam, P.; Hegde, S.; Yadav, R.; Pal, P. K.; Alladi, P. A.
10.1101/2023.10.25.563920 — neuroscience — Posted on 2023-11-20
1743 Lymphatic muscle cells are unique cells that undergo aging induced changes
Lei, P.-J.; Ruscic, K. J.; Roh, K.; Rajotte, J. J.; O'Melia, M. J.; Bouta, E. M.; Marquez, M.; Pereira, E. R.; Kumar, A. S.; Arroyo-Ataz, G.; S. Razavi, M.; Zhou, H.; Menzel, L.; Kumra, H.; Duquette, M.; Huang, P.; Baish, J. W.; Munn, L. L.; Ubellacker, J. M.; Jones, D.; Padera, T. P.
10.1101/2023.11.18.567621 — cell biology — Posted on 2023-11-19
1745 Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm
Wu, Z.; Zheng, G.; Sun, Y.; Dong, X.; Wang, Y.; Li, H.; Niu, Y.; Huang, Z.; Hu, J.; Liu, Z.
10.1101/2023.11.12.566742 — genomics — Posted on 2023-11-19
1747 Human Pancreatic α-Cell Heterogeneity and Trajectory Inference Analysis Using Integrated Single Cell- and Single Nucleus-RNA Sequencing Platforms
Kang, R. B.; Lee, J.; Varela, M.; Li, Y.; Rosselot, C.; Zhang, T.; Karakose, E.; Stewart, A. F.; Scott, D. K.; Garcia-Ocana, A.; Lu, G.
10.1101/2023.11.19.567715 — cell biology — Posted on 2023-11-19
1748 Predicting the efficacy of BH3 mimetics through the profiling of multiple protein complexes in acute myeloid leukemia
Chun, C.; Byun, J. M.; Cha, M.; Lee, H.; Choi, B.; Kim, H.; Hong, S.; Lee, Y.; Park, H.; Koh, Y.; Yoon, T.-Y.
10.1101/2023.01.16.524337 — molecular biology — Posted on 2023-11-19
1756 A step towards measuring connectivity in the deep sea: elemental fingerprints of mollusk larval shells discriminate hydrothermal sites
Mouchi, V.; Pecheyran, C.; Claverie, F.; Cathalot, C.; Matabos, M.; Germain, Y.; Rouxel, O.; Jollivet, D.; Broquet, T.; Comtet, T.
10.1101/2023.01.03.522618 — ecology — Posted on 2023-11-19
1759 Modulating Mesenchymal Stromal Cell Microenvironment Alters Exosome RNA Content and Ligament Healing Capacity
Chamberlain, C.; Prabahar, A.; Kink, J.; Mueller, E.; Li, Y.; Yopp, S.; Capitini, C.; William, M.; Hematti, P.; Vanderby, R.; Jiang, P.
10.1101/2023.10.22.563485 — cell biology — Posted on 2023-11-19
1760 Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity
Prigann, J.; Postmus, D.; Pietrobon, A. J.; Wyler, E.; Jansen, J.; Moeller, L.; Fadejeva, J.; Steijaert, T.; Fischer, C.; Koppe, U.; Gunsenheimer-Bartmeyer, B.; Meixenberger, K.; Vitcetz, S.; Sohn, M.; Loyal, L.; Thiel, A.; Sauer, S.; Sutter, K.; Dittmer, U.; Laue, M.; Bannert, N.; Landthaler, M.; GOFFINET, C.
10.1101/2020.05.04.075119 — microbiology — Posted on 2023-11-19
1761 TMS provokes target-dependent intracranial rhythms across human cortical and subcortical sites
Solomon, E. A.; Wang, J. B.; Oya, H.; Howard, M. A.; Trapp, N. T.; Uitermarkt, B. D.; Boes, A. D.; Keller, C. J.
10.1101/2023.08.09.552524 — neuroscience — Posted on 2023-11-19
1764 Noncanonical Activity of Med4 as a Gatekeeper of Metastasis through Epigenetic Control of Integrin Signaling
Bae, S.-Y.; Chen, Y.; Chen, H.; Kumar, D.; Karaiskos, S.; Xu, J. J.; Lu, C.; Viny, A. D.; Giancotti, F. G.
10.1101/2023.11.18.566087 — cancer biology — Posted on 2023-11-19
1766 DL4MicEverywhere: Deep learning for microscopy made flexible, shareable, and reproducible
Hidalgo-Cenalmor, I.; Pylvänäinen, J. W.; Ferreira, M. G.; Russell, C. T.; Arganda-Carreras, I.; AI4Life Consortium, ; Jacquemet, G.; Henriques, R.; Gomez-de-Mariscal, E.
10.1101/2023.11.19.567606 — bioinformatics — Posted on 2023-11-19
1770 Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study
Kahraman, K.; Robson, S. A.; Gocenler, O.; Yenici, C. M.; Tozkoparan, C. D.; Klein, J. M.; Dötsch, V.; Haas, A. L.; Ziarek, J. J.; Dag, C.
10.1101/2023.04.13.536743 — biochemistry — Posted on 2023-11-19
1772 A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis
Vukadin, L.; Park, B.; Mohamed, M.; Li, H.; Elkholy, A.; Torrelli-Diljohn, A.; Kim, J.-H.; Jeong, K.; Murphy, J. M.; Harvey, C. A.; Dunlap, S.; Gehrs, L.; Lee, H.; Kim, H.-G.; Lee, S. N.; Stanford, D.; Barrington, R. A.; Foote, J.; Sorace, A. G.; Welner, R. S.; Hildreth, B. E.; Lim, S.-T. S.; Ahn, E.-Y. E.
10.1101/2023.11.19.567732 — genetics — Posted on 2023-11-19
1773 Challenges in estimating species age from phylogenetic trees
Calderon del Cid, C.; Hauffe, T.; Carrillo, J. D.; Warnock, R. C. M.; Silvestro, D.
10.1101/2023.11.19.567731 — evolutionary biology — Posted on 2023-11-19
1777 Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge Model
Wang, X.; Su, H.; Wallach, J. B.; Wagner, J. C.; Braunecker, B. J.; Gardner, M.; Guinn, K. M.; Klevorn, T.; Lin, K.; Liu, Y. J.; Liu, Y.; Mugahid, D.; Rodgers, M.; Sixsmith, J.; Wakabayashi, S.; Zhu, J.; Zimmerman, M.; Dartois, V.; Flynn, J. L.; Lin, P. L.; Ehrt, S.; Fortune, S. M.; Rubin, E. J.; Schnappinger, D.
10.1101/2023.11.19.567569 — microbiology — Posted on 2023-11-19
1779 Contemporary HIV-1 consensus Env with redesigned hypervariable loops promote antibody binding
Bai, H.; Lewitus, E.; Li, Y.; Dussupt, V.; Slike, B.; Mendez-Rivera, L.; Schmid, A.; Wieczorek, L.; Polonis, V.; Krebs, S. J.; Ake, J. A.; Vasan, S.; Joyce, M. G.; Townsley, S.; Rolland, M.
10.1101/2023.11.19.567729 — microbiology — Posted on 2023-11-19
1784 Brd2 is dispensable for genome compartmentalization and replication timing
Hinojosa-Gonzalez, L.; Turner, J. L.; Sasaki, T.; Ay, F.; Gilbert, D. M.
10.1101/2023.11.17.567572 — genomics — Posted on 2023-11-19
1786 Viral expansion after transfer is a primary driver of influenza A virus transmission bottlenecks
Holmes, K. E.; VanInsberghe, D.; Ferreri, L. M.; Elie, B.; Ganti, K.; Lee, C.-Y.; Lowen, A. C.
10.1101/2023.11.19.567585 — microbiology — Posted on 2023-11-19
1787 Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro, V.; Bertol, J.; Gutierrez, C.; Palacios, A.; Pasquina-Lemonche, L.; Espalliat, A.; Lerma, L.; Weinrick, B.; Lavin, J. L.; Elortza, F.; Azkalgorta, M.; Prieto, A.; Buendia-Nacarino, P.; Luque-Garcia, J. L.; Neyrolles, O.; Cava, F.; Hobbs, J.; Sanz, J.; Prados-Rosales, R.
10.1101/2023.11.19.567727 — microbiology — Posted on 2023-11-19
1789 Unveiling unique microbial nitrogen cycling and novel nitrification drivers in coastal Antarctica
Han, P.; Tang, X.; Koch, H.; Dong, X.; Hou, L.; Wang, D.; Zhao, Q.; Li, Z.; Liu, M.; Luecker, S.; Shi, G.
10.1101/2023.11.19.566674 — microbiology — Posted on 2023-11-19
1790 Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits
Schmidt, A. K.; Schwartzkopf, C. M.; Pourtois, J. D.; Burgener, E.; Faith, D. R.; Joyce, A.; Lamma, T.; Kumar, G.; Bollyky, P. L.; Secor, P. R.
10.1101/2023.11.19.567716 — microbiology — Posted on 2023-11-19
1794 Misexpression of inactive genes in whole blood is associated with nearby rare structural variants
Vanderstichele, T.; Burnham, K. L.; de Klein, N.; Tardaguila, M.; Howell, B.; Walter, K.; Kundu, K.; Koeppel, J.; Lee, W.; Tokolyi, A.; Persyn, E.; Nath, A. P.; Marten, J.; Petrovski, S.; Roberts, D. J.; Di Angelantonio, E.; Danesh, J.; Berton, A.; Platt, A.; Butterworth, A. S.; Soranzo, N.; Parts, L.; Inouye, M.; Paul, D. S.; Davenport, E. E.
10.1101/2023.11.17.567537 — genetics — Posted on 2023-11-19
1797 The Lifeact-EGFP Quail: A New Avian Model for Studying Actin Dynamics In Vivo
Alvarez, Y. D.; van der Spuy, M.; Wang, J. X.; Noordstra, I.; Tan, S. Z.; Carroll, M.; Yap, A. S.; Serralbo, O.; White, M. D.
10.1101/2023.11.19.567639 — developmental biology — Posted on 2023-11-19
1798 Pathogen-prey-predator relations of avian raptors during epizootics of highly pathogenic avian influenza virus HPAIV H5N1 (clade 2.3.4.4b) in Germany
Günther, A.; Krone, O.; Globig, A.; Pohlmann, A.; King, J.; Fast, C.; Grund, C.; Hennig, C.; Herrmann, C.; Piro, S.; Rubbenstroth, D.; Schulz, J.; Staubach, C.; Stacker, L.; Ulrich, L.; Ziegler, U.; Harder, T.; Beer, M.
10.1101/2023.11.19.567176 — microbiology — Posted on 2023-11-19
1799 RORγ bridges cancer-driven lipid dysmetabolism and myeloid immunosuppression
Bleve, A.; Consonni, F. M.; Incerti, M.; Garlatti, V.; Pandolfo, C.; Monari, M. N.; Serio, S.; Pistillo, D.; Sironi, M.; Ali, C.; Manfredi, M.; Finocchiaro, G.; Panico, C.; Condorelli, G.; Sica, A.
10.1101/2023.11.19.567414 — immunology — Posted on 2023-11-19
1801 Emergence of the Novel Infectious bursal disease viruse Variant in Vaccinated Poultry Flocks in Egypt
Shahin, M. A.; Sultan, H. A.; Zanaty, A.; Mosaad, Z.; Hagage, N. M.; Adel, A.; Selim, K.; Saied, D.; Samir, A. H.; Erfan, A.; Selim, A.; Samy, M.; Naguib, M. M.; Hassan, H.; El Shazly, O.; Elbade, Z. A.; Kamel, M.; Farghaly, E.; Eid, S.; El Shahaby, M.; Hamoud, M. M.; Mehana, O.; Nabeh, M.; Samy, A.
10.1101/2023.11.13.566865 — microbiology — Posted on 2023-11-19
1811 CHRNA5 links chandelier cells to severity of amyloid pathology in human aging and Alzheimer's Disease
Rybnicek, J.; Chen, Y.; Milic, M.; Tio, E.; McLaurin, J.; Hohman, T. J.; De Jager, P.; Schneider, J. A.; Wang, Y.; Bennett, D. A.; Tripathy, S.; Felsky, D.; Lambe, E. K.
10.1101/2022.05.03.490491 — neuroscience — Posted on 2023-11-18
1812 Proximity Proteome Analysis Reveals Novel TREM2 Interactors in the ER-Mitochondria Interface of Human Microglia
Kwak, C.; Finan, G. M.; Park, Y. R.; Garg, A.; Harari, O.; Mun, J. Y.; Rhee, H.-W.; Kim, T.-W.
10.1101/2023.03.21.533722 — neuroscience — Posted on 2023-11-18
1816 Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina
James, R. E.; Hamilton, N. R.; Huffman, L. N.; Pasterkamp, J.; Goff, L. A.; Kolodkin, A. L.
10.1101/2023.11.18.567662 — neuroscience — Posted on 2023-11-18
1822 Optogenetic control of lysosome function
Ilyinsky, N. S.; Bukhalovich, S. M.; Bagaeva, D. F.; Nesterov, S. V.; Alekseev, A. A.; Tsybrov, F. M.; Bogorodskiy, A. O.; Alekhin, V. A.; Nazarova, S. F.; Moiseeva, O. V.; Vlasova, A. D.; Kovalev, K. V.; Mikhailov, A. E.; Rogachev, A. V.; Bamberg, E.; Borshchevskiy, V. I.; Gordeliy, V. I.
10.1101/2023.08.02.551716 — cell biology — Posted on 2023-11-18
1823 The role of desmoplakin for neuronal function in the dentate gyrus and anxiety-related behavior
Otsubo, K.; Sakashita, N.; Nishimoto, Y.; Sato, Y.; Kobayashi, K.; Suzuki, K.; Segi-Nishida, E.
10.1101/2023.11.17.567646 — neuroscience — Posted on 2023-11-18
1826 Control of T-shaped Bifurcation by Multiple Guidance Mechanisms during Dorsal Funiculus Development in the Spinal Cord
Curran, B. M.; Nickerson, K. R.; Yung, A. R.; Goodrich, L. V.; Jaworski, A.; Tessier-Lavigne, M.; Ma, L.
10.1101/2023.11.17.567638 — neuroscience — Posted on 2023-11-18
1831 Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach
Hilmi, M.; Delecourt, F.; Raffenne, J.; Bourega, T.; Dusetti, N. J.; Iovanna, J.; Blum, Y.; Richard, M.; Neuzillet, C.; Couvelard, A.; De Mestier, L.; Rebours, V.; Nicolle, R.; Cros, J.
10.1101/2023.11.16.567454 — cancer biology — Posted on 2023-11-18
1833 Chromosome-level scaffolding of haplotype-resolved assemblies using Hi-C data without reference genomes
Zeng, X.; Yi, Z.; Zhang, X.; Du, Y.; Li, Y.; Zhou, Z.; Chen, S.; Zhao, H.; Yang, S.; Wang, Y.; Chen, G.
10.1101/2023.11.18.567668 — bioinformatics — Posted on 2023-11-18
1836 The quest for improved biohydrogen formation: are heat shocks the solution?
Barth, M.; Werner, M.; Otto, P.; Richwien, B.; Bahramsari, S.; Krause, M.; Schwan, B.; Abendroth, C.
10.1101/2023.11.18.567651 — bioengineering — Posted on 2023-11-18
1839 Senescence suppresses the integrated stress response and activates a stress-enhanced secretory phenotype
Payea, M. J.; Dar, S. A.; Anerillas, C. A.; Martindale, J. L.; Belair, C.; Munk, R.; Malla, S.; Fan, J.; Piao, Y.; Yang, X.; Rehman, A.; Banskota, N.; Abdelmohsen, K.; Gorospe, M.; Maragkakis, M.
10.1101/2023.04.12.536613 — molecular biology — Posted on 2023-11-18
1840 Herbivore insect small RNA effector suppress plant defense by cross-kingdom gene silencing
Han, W.-H.; Ji, S.-X.; Zhang, F.-B.; Song, H.-D.; Wang, J.-X.; Xie, R.; Wang, X.-W.
10.1101/2023.11.18.567654 — molecular biology — Posted on 2023-11-18
1841 Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.
Hayes, B. K.; Harper, M.; Venugopal, H.; Lewis, J. M.; Wright, A.; Steele, J. R.; Steer, D.; Schittenhelm, R. B.; Boyce, J. D.; McGowan, S.
10.1101/2023.11.18.567679 — microbiology — Posted on 2023-11-18
1844 Network and State Specificity in Connectivity-Based Predictions of Individual Behavior
Kraljevic, N.; Langner, R.; Küppers, V.; Raimondo, F.; Patil, K. R.; Eickhoff, S. B.; Müller, V. I.
10.1101/2023.05.11.540387 — neuroscience — Posted on 2023-11-18
1846 Bacterial assembly in the switchgrass rhizosphere is shaped by phylogeny, host genotype, and growing site.
Sutherland, J.; Bell, T. H.; Bonos, S.; Tkach, C.; Hansen, J.; Crawford, R.; Carlson, J. E.; Lasky, J. R.
10.1101/2023.11.15.567221 — plant biology — Posted on 2023-11-18
1848 Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation
Ogoke, O.; Guiggey, D.; Chiang, A.; Thompson, S.; Nguyen, T. H. A.; Berke, D.; Ott, C.; Kalinousky, A.; Shamul, C.; Chen, P.; Ross, S.; Chen, Z.; Srivastava, P.; Gaughan, C.; Mahajan, S. D.; Zhao, R.; Gunawan, R.; Parashurama, N.
10.1101/2022.07.24.501313 — bioengineering — Posted on 2023-11-18
1849 Droplet bioprinting of acellular and cell-laden structures at high-resolutions
Kunwar, P.; Aryal, U.; Poudel, A.; Fougnier, D.; Geffert, Z. J.; Xie, R.; Li, Z.; Soman, P.
10.1101/2023.11.18.567660 — bioengineering — Posted on 2023-11-18
1850 Small variant benchmark from a complete assembly of X and Y chromosomes
Wagner, J.; Olson, N. D.; McDaniel, J.; Harris, L.; Pinto, B. J.; Jaspez, D.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Lorenzo-Salazar, J. M.; Flores, C.; Sahraeian, S. M. E.; Narzisi, G.; Byrska-Bishop, M.; Evani, U. S.; Xiao, C.; Lake, J. A.; Fontana, P.; Greenberg, C.; Freed, D.; Boutros, P. C.; Mootor, M. F. E.; Murray, L.; Shafin, K.; Carroll, A.; Sedlazeck, F. J.; Wilson, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2023.10.31.564997 — genomics — Posted on 2023-11-18
1851 Lymphatic muscle cells are unique cells that undergo aging induced changes
Lei, P.-J.; Ruscic, K. J.; Roh, K.; Rajotte, J. J.; O'Melia, M. J.; Bouta, E. M.; Marquez, M.; Pereira, E. R.; Kumar, A. S.; Arroyo-Ataz, G.; S. Razavi, M.; Zhou, H.; Menzel, L.; Kumra, H.; Duquette, M.; Huang, P.; Baish, J. W.; Munn, L. L.; Ubellacker, J. M.; Jones, D.; Padera, T. P.
10.1101/2023.11.18.567621 — cell biology — Posted on 2023-11-18
1852 Control of Biofilm Formation by an Agrobacterium tumefaciens Pterin-Binding Periplasmic Protein Conserved Among Pathogenic Bacteria
Greenwich, J.; Eagan, J. L.; Feirer, N.; Boswinkle, K.; Minasov, G. A.; Shuvaloca, L.; Inniss, N.; Raghava, J.; Ghosh, A.; Satchell, K. J.; Allen, K. D.; Fuqua, C.
10.1101/2023.11.18.567607 — microbiology — Posted on 2023-11-18
1853 Guanylate cyclase activity of TIR1/AFB auxin receptorsin rapid auxin responses
Qi, L.; Kwiatkowski, M.; Kulich, I.; Chen, H.; Gao, Y.; Yun, P.; Li, L.; Shabala, S.; Farmer, E.; Jaworski, K.; Friml, J.
10.1101/2023.11.18.567481 — plant biology — Posted on 2023-11-18
1857 Cell morphology QTL reveal gene by environment interactions in a genetically diverse cell population
O'Connor, C.; Keele, G. R.; Martin, W.; Stodola, T.; Gatti, D.; Hoffman, B. R.; Korstanje, R.; Churchill, G. A.; Reinholdt, L. G.
10.1101/2023.11.18.567597 — genetics — Posted on 2023-11-18
1858 Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult Mice
Tai, W. L.; Cho, K.-S.; Kriukov, E.; Ashok, A.; Wang, X.; Monavarfeshani, A.; Yan, W.; Li, Y.; Guan, T.; Sanes, J. R.; Baranov, P.; Chen, D. F.
10.1101/2023.11.17.567614 — neuroscience — Posted on 2023-11-18
1859 Optical constraints on two-photon voltage imaging
Davis, H. C.; Brooks, F. P.; Wong-Campos, J. D.; Cohen, A. E.
10.1101/2023.11.18.567441 — neuroscience — Posted on 2023-11-18
1860 Evolution is All You Need in Promoter Design and Optimization
Ren, R.; Yu, H.; Teng, J.; Mao, S.; Bian, Z.; Tao, Y.; Yau, S. S.-T.
10.1101/2023.11.18.567645 — synthetic biology — Posted on 2023-11-18
1861 Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway
Grilo, L. F.; Zimmerman, K. D.; Puppala, S.; Chan, J.; Huber, H. F.; Li, G.; Jadhav, A. Y. L.; Wang, B.; Li, C.; Clarke, G. D.; Register, T. C.; Oliveira, P. J.; Nathanielsz, P. W.; Olivier, M.; Pereira, S.; Cox, L. A.
10.1101/2023.11.17.567640 — molecular biology — Posted on 2023-11-18
1864 DFNA5-mediated pyroptosis is a driver for venetoclax and azacytidine synergy in myeloid leukemia
Mahesh, A. N.; Lai XIN-Yi, J.; Tng Jia Lin, M.; Lin, W.; Wan, J. C.; Yoon, J.; Chen, K.; Bhatt, S.
10.1101/2023.11.17.567421 — cancer biology — Posted on 2023-11-18
1865 A liquid-to-solid phase transition of biomolecular condensates drives in vivo formation of yeast amyloids and prions
Alieva, M. K.; Nikishina, S. B.; Kireev, I. I.; Golyshev, S. A.; Tyurin-Kuzmin, P. A.; Ivanova, L. V.; Alexandrov, A. I.; Kushnirov, V. V.; Dergalev, A. A.
10.1101/2023.11.17.566816 — biochemistry — Posted on 2023-11-18
1868 Control of T-shaped Bifurcation by Multiple Guidance Mechanisms during Dorsal Funiculus Development in the Spinal Cord
Curran, B. M.; Nickerson, K. R.; Yung, A. R.; Goodrich, L. V.; Jaworski, A.; Tessier-Lavigne, M.; Ma, L.
10.1101/2023.11.17.567638 — neuroscience — Posted on 2023-11-18
1870 Efficient and sustained optogenetic control of nervous and cardiac systems
Zerche, M.; Hunniford, V.; Alekseev, A.; El May, F.; Vavakou, A.; Siegenthaler, D.; Hueser, M. A.; Kiehn, S. M.; Garrido-Charles, A.; Alvanos, T.; Witzke, I.; Trenholm, S.; Mace, E.; Kusch, K.; Bruegmann, T.; Wolf, B. J.; Mager, T.; Moser, T.
10.1101/2023.11.17.567544 — biophysics — Posted on 2023-11-18
1878 Inositolphosphate glycans accumulate and suppress plant defense during Arabidopsis/Botrytis interaction
Lelas, L.; Rouffet, J.; Filachet, A.; Sechet, J.; Akary, E.; Desprez, T.; Vernhettes, S.; Voxeur, A.
10.1101/2023.11.16.567443 — plant biology — Posted on 2023-11-18
1879 The Endothelium Modulates the Prothrombotic Phenotype of Factor V Leiden: Evidence from an Ex Vivo Model
Schwarz, N.; Muller, J.; McRae, H. L.; Reda, S.; Pezeshkpoor, B.; Oldenburg, J.; Potzsch, B.; Ruhl, H.
10.1101/2023.11.15.567299 — pathology — Posted on 2023-11-18
1881 Ultrasensitive allele inference from immune repertoire sequencing data with MiXCR
Mikelov, A.; Nefedev, G.; Tashkeev, A.; Rodriguez, O. L.; Ortmans, D. A.; Skatova, V.; Izraelson, M.; Davydov, A.; Poslavsky, S.; Rahmouni, S.; Watson, C. T.; Chudakov, D.; Boyd, S. D.; Bolotin, D. A.
10.1101/2023.10.10.561703 — immunology — Posted on 2023-11-18
1882 Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3
Hathaway, N. J.; Kim, I. E.; Young, N. W.; Hui, S. T.; Crudale, R.; Giesbrecht, D.; Liang, E. Y.; Nixon, C. P.; Juliano, J. J.; Parr, J. B.; Bailey, J. A.
10.1101/2022.12.07.519189 — genomics — Posted on 2023-11-17
1883 Aberrant landscapes of maternal meiotic crossovers contribute to aneuploidies in human embryos
Ariad, D.; Madjunkova, S.; Madjunkov, M.; Chen, S.; Abramov, R.; Librach, C.; McCoy, R. C.
10.1101/2023.06.07.543910 — genomics — Posted on 2023-11-17
1884 Integrative multiomics analysis of neointima proliferation in human saphenous vein: implications for bypass graft disease
Kim, D.; Goo, B.; Shi, H.; Coffey, P.; Veerapaneni, P.; Chouhaita, R.; Cyriac, N.; Aboud, G.; Cave, S.; Greenway, J.; Mundkur, R.; Ahmadieh, S.; Harb, R.; Ogbi, M.; Fulton, D. J.; Huo, Y.; Zhang, W.; Long, X.; Guha, A.; Kim, H. W.; Shi, Y.; Rice, R. D.; Gallo, D. R.; Patel, V.; Lee, R.; Weintraub, N. L.
10.1101/2023.11.14.567053 — genomics — Posted on 2023-11-17
1885 MAVISp: A Modular Structure-Based Framework for Genomic Variant Interpretation
Arnaudi, M.; Beltrame, L.; Degn, K.; Utichi, M.; Scrima, S.; Sanchez Izquierdo, P.; Krzesinska, K.; Maselli, F.; Dorcakova, T.; Safer, J.; Estad, A. H.; Meldgard, K.; Becker, P.; Bruun Brockhoff, J.; Drud Nielsen, A.; Sora, V.; Pettenella, A.; Vinhas, J.; Sackett, P. W.; Cava, C.; Rohlin, A.; Nilbert, M.; Iqbal, S.; Lambrughi, M.; Tiberti, M.; Papaleo, E.
10.1101/2022.10.22.513328 — bioinformatics — Posted on 2023-11-17
1887 Identification of 1600 replication origins in S. cerevisiae
Foss, E. J.; Lichauco, C.; Gatbonton-Schwager, T.; Lofts, B.; Lao, U.; Bedalov, A.
10.1101/2023.04.11.536402 — genetics — Posted on 2023-11-17
1889 TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo
Kime, J.; Bose, D.; Arainga, M.; Haque, M. R.; Fennessey, C. M.; Caddell, R. A.; Thomas, Y.; Ferrell, D. E.; Ali, S.; Grody, E.; Goyal, Y.; Cicala, C.; Arthos, J.; Keele, B. F.; Vaccari, M.; Lorenzo-Redondo, R.; Hope, T. J.; Villinger, F. J.; Marinelli, E.
10.1101/2023.09.05.556422 — immunology — Posted on 2023-11-17
1893 The multilevel society of proboscis monkeys with a possible patrilineal basis
Matsuda, I.; Murai, T.; Grueter, C. C.; Tuuga, A.; Goossens, B.; Bernard, H.; Yahya, N. K.; Orozco-terWengel, P.; Salgado-Lynn, M.
10.1101/2023.01.24.525467 — animal behavior and cognition — Posted on 2023-11-17
1898 Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during aging
Saeedi Saravi, S. S.; Pugin, B.; Constancias, F.; Thomas, A.; Le Gludic, S.; Allemann, M. S.; Karsai, G.; Lee, P.; Menni, C.; Attaye, I.; Beer, J. H.
10.1101/2023.11.17.567594 — cell biology — Posted on 2023-11-17
1899 Mitochondrial genomes of Pleistocene megafauna retrieved from recent sediment layers of two Siberian lakes
Seeber, P. A.; Batke, L.; Dvornikiv, Y.; Schmidt, A. A.; Wang, Y.; Stoof-Leichsenring, K.; Moon, K.; Vohr, S.; Shapiro, B.; Epp, L.
10.1101/2023.06.16.545324 — molecular biology — Posted on 2023-11-17
1900 JUN mRNA Translation Regulation is Mediated by Multiple 5' UTR and Start Codon Features
Gonzalez-Sanchez, A. M.; Castellanos-Silva, E. A.; Diaz-Figueroa, G.; Cate, J. H. D.
10.1101/2023.11.17.567602 — molecular biology — Posted on 2023-11-17
1906 Connectivity Regression
Desai, N.; Baladandayuthapani, V.; Shinohara, R. T.; Morris, J.
10.1101/2023.11.14.567081 — neuroscience — Posted on 2023-11-17
1909 The biophysical basis of bacterial colony growth
Pokhrel, A. R.; Steinbach, G.; Krueger, A.; Day, T. C.; Tijani, J.; Hammer, B. K.; Yunker, P. J.
10.1101/2023.11.17.567592 — biophysics — Posted on 2023-11-17
1910 Monocyte subpopulations exhibit distinct TNF-dependent aging signatures.
Bentz, A. W.; Monica Gutierrez, M.; Loukov, D.; Eckman, B.; Gadhvi, G.; Cuda, C.; Bowdish, D.; Winter, D. R.
10.1101/2023.11.17.567601 — genomics — Posted on 2023-11-17
1911 Long-distance communication can enable collective migration in a dynamic seascape
Dodson, S.; Oestreich, W. K.; Savoca, M. S.; Hazen, E. L.; Bograd, S. J.; Ryan, J. P.; Fiechter, J.; Abrahms, B.
10.1101/2023.11.17.567622 — ecology — Posted on 2023-11-17
1912 A human immune/muscle xenograft model of FSHD muscle pathology
Daman, K.; Yan, J.; Burzenski, L. M.; Kady, J.; Shultz, L. D.; Brehm, M. A.; Emerson, C. P.
10.1101/2023.11.17.567590 — immunology — Posted on 2023-11-17
1913 Protein-lipid interactions drive presynaptic assembly upstream of cell adhesion molecules
Frankel, E. B.; Tiroumalechetty, A. R.; Henry, P. S.; Su, Z.; Wu, Y.; Kurshan, P. T.
10.1101/2023.11.17.567618 — neuroscience — Posted on 2023-11-17
1916 A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate
Chavan, A.; Isenhart, R.; Nguyen, S. C.; Kotb, N.; Harke, J.; Sintsova, A.; Ulukaya, G.; Uliana, F.; Ashiono, C.; Kutay, U.; Pegoraro, G.; Rangan, P.; Joyce, E. F.; Jagannathan, M.
10.1101/2023.11.17.567611 — cell biology — Posted on 2023-11-17
1919 Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response
Nyirenda, J.; Hardy, O.; Silva Filho, J. L.; Herder, V.; Attipa, C.; Ndovi, C.; Siwombo, M.; Namalima, T.; Suwedi, L.; Nyasulu, W.; Ngulube, T.; Nyirenda, D.; Mvaya, L.; Phiri, J.; Chasweka, D.; Eneya, C.; Makwinja, C.; Phiri, C.; Ziwoya, F.; Tembo, A.; Makwangwala, K.; Khoswe, S.; Banda, P.; Morton, B.; Hilton, O.; Lawrence, S.; Frere dos Reis, M.; Cardoso Melo, G.; Vinicious Guimaros de Lecerda, M.; Trindande Maranhao Costa, F.; Marcelo Monteiro, W.; Carlos de Lima Fereirra, L.; Johnson, C.; Mcguinness, D.; Jambo, K.; Haley, M. J.; Kumwenda, B.; Palmarini, M.; Barnes, K. G.; Denno, D. M.; Vo
10.1101/2023.11.16.566964 — immunology — Posted on 2023-11-17
1921 Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy
Whitney, K.; Song, W.-m.; Sharma, A.; Dangoor, D. K.; Farrell, K.; Krassner, M. M.; Ressler, H. W.; Christie, T. D.; Walker, R. H.; Nirenberg, M. J.; Zhang, B.; Frucht, S. J.; Riboldi, G. M.; Crary, J. F.; Pereira, A.
10.1101/2023.11.17.567587 — neuroscience — Posted on 2023-11-17
1922 Microglia undergo transcriptional, translational and functional adaptations to dark and light phases in laboratory mice
Mattei, D.; Ivanov, A.; Hammer, J.; Ugursu, B.; Schalbetter, S.; Richetto, J.; Weber-Stadelbauer, U.; Mueller, F.; Scarborough, J.; Wolf, S. A.; Kettenmann, H.; Wollscheid, B.; Beule, D.; Meyer, U.
10.1101/2023.11.17.567571 — neuroscience — Posted on 2023-11-17
1924 Insulin at the Intersection of Thermoregulation and Glucose Homeostasis
Winn, N. C.; Schleh, M. W.; Garcia, J. N.; Lantier, L.; McGuinness, O. P.; Blair, J. A.; Hasty, A. H.; Wasserman, D. H.
10.1101/2023.11.17.566254 — physiology — Posted on 2023-11-17
1925 Targeting pediatric High-Grade Gliomas with OAcGD2-CAR Vδ2 T cells
Thomas, P.; Veerasamy, M.; Devinat, M.; Guiet, E.; Ollier, J.; Paris, P.; Entz-Werle, N.; Gratas, C.; Clemenceau, B.; Birkle, S.; Paris, F.; Pecqueur, C.; Fougeray, S.
10.1101/2023.11.17.567375 — cancer biology — Posted on 2023-11-17
1926 Deep learning and direct sequencing of labeled RNA captures transcriptome dynamics
Martinek, V.; Martin, J.; Belair, C.; Payea, M. J.; Malla, S.; Alexiou, P.; Maragkakis, M.
10.1101/2023.11.17.567581 — bioinformatics — Posted on 2023-11-17
1927 Determinants of spring migration departure dates in a New World sparrow: weather variables reign supreme
Byrd, A. J.; Talbott, K. M.; Smiley, T. M.; Verrett, T. B.; Gross, M.; Hladik, M. L.; Ketterson, E. D.; Becker, D.
10.1101/2023.11.17.567563 — ecology — Posted on 2023-11-17
1928 Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling.
Saunders, N.; Monel, B.; Cayet, N.; Archetti, L.; Moreno, H.; Jeanne, A.; Marguier, A.; Wai, T.; Schwartz, O.; Frechin, M.
10.1101/2023.11.16.567378 — cell biology — Posted on 2023-11-17
1931 Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers
Bricio Moreno, L.; Barreto de Albuquerque, J.; Neary, J. M.; Nguyen, T.; Hastie, K. M.; Landeras-Bueno, S.; Hariharan, C.; Nathan, A.; Getz, M. A.; Gayton, A. C.; Khatri, A.; Gaiha, G. D.; Saphire, E. O.; Luster, A. D.; Moon, J. J.
10.1101/2023.11.16.566918 — immunology — Posted on 2023-11-17
1932 Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior
Vu, M.-A. T.; Brown, E. H.; Wen, M. J.; Noggle, C. A.; Zhang, Z.; Monk, K. J.; Bouabid, S.; Mroz, L.; Graham, B. M.; Zhuo, Y.; Li, Y.; Otchy, T. M.; Tian, L.; Davison, I. G.; Boas, D. A.; Howe, M. W.
10.1101/2023.11.17.567425 — neuroscience — Posted on 2023-11-17
1934 A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation.
Chen, L.; Xu, G.; Song, X.; Zhang, L.; Chen, C.; Xiang, G.; Wang, S.; Zhang, Z.; Wu, F.; Yang, X.; Zhang, L.; Ma, X.; Yu, J.
10.1101/2023.11.15.567291 — cancer biology — Posted on 2023-11-17
1935 De novo lipogenesis pathway is a vulnerability in IDH1 mutant glioma
Elahi, L. S.; Condro, M.; Kawaguchi, R.; Qin, Y.; Alvarado, A. G.; Gruender, B.; Stewart, H.; Li, T.; Lai, A.; Garrett, M.; Castro, M.; Lowenstein, P. R.; Kornblum, H.
10.1101/2023.11.15.567231 — cancer biology — Posted on 2023-11-17
1936 The MYC axis in advanced prostate cancer is impacted through concurrent targeting of ERβ and AR using a novel ERβ-selective ligand alongside Enzalutamide
Gray, J. S.; Wani, S. A.; Hussain, S.; Huang, P.; Nayak, D.; Long, M. D.; Yates, C.; Clinton, S. K.; Bennett, C. E.; Coss, C. C.; Campbell, M. J.
10.1101/2023.11.15.567282 — cancer biology — Posted on 2023-11-17
1937 Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancer
Colling, K. E.; Symons, E. L.; Buroni, L.; Sumanasiri, H. K.; Andrew-Udoh, J.; Witt, E.; Losh, H. A.; Morrison, A. M.; Leslie, K. K.; Dunnill, C. J.; De Bono, J. S.; Thiel, K. W.
10.1101/2023.11.15.567243 — cancer biology — Posted on 2023-11-17
1938 Metabolic and imaging phenotypes associated with RB1 loss in castrate resistant prostate cancer
Ahmad, F.; White, M.; Yamamoto, K.; Crooks, D. R.; Agarwal, S.; Yang, Y.; Capaldo, B.; Raj, S.; Alilin, A. N.; Ton, A.; Adler, S.; Seidel, J.; Olkowski, C.; Cherukuri, M. K.; Choyke, P. L.; Kelly, K.; Brender, J. R.
10.1101/2023.11.15.567250 — cancer biology — Posted on 2023-11-17
1939 NK cells shape the clonal evolution of B-ALL cells by IFN-γ production
Buri, M. C.; Shoeb, M. R.; Bykov, A.; Repiscak, P.; Baik, H.; Dupanovic, A.; David, F. O.; Kovacic, B.; Hall-Glenn, F.; Urbanus, J.; Sippl, L.; Stofner, S.; Emminger, D.; Cosgrove, J.; Lehner, M.; Perie, L.; Shumacher, T. N.; Gotthardt, D.; Halbritter, F.; Putz, E. M.
10.1101/2023.11.16.567430 — cancer biology — Posted on 2023-11-17
1942 CRISPR-Cas13d screens identify KILR a breast cancer risk-associated lncRNA that regulates DNA replication and repair.
Wang, L.; Bitar, M.; Lu, X.; Jacquelin, S.; Nair, S.; Sivakumaran, H.; Hillman, K. M.; Kaufmann, S.; Ziegman, R.; Casciello, F.; Gowda, H.; Rosenbluh, J.; Edwards, S. L.; French, J. D.
10.1101/2023.11.16.567471 — cancer biology — Posted on 2023-11-17
1943 The T Cell Receptor beta Chain Repertoire of Tumor Infiltrating Lymphocytes Improves Neoantigen Prediction and Prioritization
Pham, T. M. Q.; Nguyen, T. N.; Nguyen, B. Q. T.; Nguyen, H. T. P.; Tran, T. P. D.; Pham, N. M. D.; Ho, T. K. C.; Nguyen, D. V. L.; Nguyen, H. T.; Tran, D. H.; Tran, T. S.; Pham, T.-V. N.; Le, M.-T.; Nguyen, T. T. V.; Phan, M.-D.; Giang, H.; Nguyen, H.-N.; Tran, L. S.
10.1101/2023.11.16.567478 — cancer biology — Posted on 2023-11-17
1944 Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment
Soupir, A. C.; Hayes, M. T.; Peak, T. C.; Ospina, O. E.; Chakiryan, N. H.; Berglund, A. E.; Stewart, P. A.; Nguyen, J. V.; Segura, C. M. M.; Francis, N. L.; Echevarria, P. M. R.; Chahoud, J.; Li, R.; Tsai, K. Y.; Blasi, J. A.; Perez, Y. C.; Dhillon, J.; Martinez, L. A.; Gloria, W. E.; Schurman, N.; Kim, S.; Gregory, M.; Mule, J. J.; Fridley, B. L.; Manley, B. J.
10.1101/2023.11.16.567457 — cancer biology — Posted on 2023-11-17
1946 Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach
Hilmi, M.; Delecourt, F.; Raffenne, J.; Bourega, T.; Dusetti, N. J.; IOVANNA, J. L.; Blum, Y.; Richard, M.; Neuzillet, C.; Couvelard, A.; De Mestier, L.; Rebours, V.; NICOLLE, R.; Cros, J.
10.1101/2023.11.16.567454 — cancer biology — Posted on 2023-11-17
1947 Enhancer heterogeneity of lung neuroendocrine tumors reveals sensitivity to FGF signaling inhibition
Davis, E.; Avniel-Polak, S.; Abu-Kamel, S.; Antman, I.; Saadoun, T.; Brim, C.; Bel-Ange, A.; Atlan, K.; Tzur, T.; Abu-Akar, F.; Wald, O.; Izhar, U.; Hecht, M.; Grozinsky-Glasberg, S.; Drier, Y.
10.1101/2023.11.17.566871 — cancer biology — Posted on 2023-11-17
1950 Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a
Olivi, L.; Bagchus, C.; Pool, V.; Bekkering, E.; Speckner, K.; Wu, W.; Martens, K.; van der Oost, J.; Staals, R.; Hohlbein, J.
10.1101/2023.11.16.567366 — biophysics — Posted on 2023-11-17
1953 Deep learning assisted single particle tracking for automated correlation between diffusion and function
Kaestel-Hansen, J.; de Sautu, M.; Saminathan, A.; Scanavachi, G.; Correia, R. F. B. D. C.; Nielsen, A. J.; Bleshoy, S. V.; Boomsma, W.; Kirchhausen, T.; Hatzakis, N. S.
10.1101/2023.11.16.567393 — biophysics — Posted on 2023-11-17
1954 Pooled optical screening in bacteria using chromosomally expressed barcodes
Soares, R. R. G.; Garcia-Soriano, D. A.; Larsson, J.; Fange, D.; Schirman, D.; Grillo, M.; Knöppel, A.; Sen, B. C.; Svahn, F.; Zikrin, S.; Nilsson, M.; Elf, J.
10.1101/2023.11.17.567382 — biophysics — Posted on 2023-11-17
1955 The Role of Electron Spin-Polarizability and Charge Dynamics in Protein Function
Vyas, P.; Santra, K.; Preeyanka, N.; Gupta, A.; Weil-Ktorza, O.; Zhu, Q.; Longo, L. M.; Fransson, J.; Metanis, N.; Naaman, R.
10.1101/2023.11.16.567399 — biophysics — Posted on 2023-11-17
1958 Ice formation and its elimination in cryopreservation of bovine oocytes
Abdelhady, A. W.; Mittan-Moreau, D. W.; Crane, P. L.; McLeod, M. J.; Cheong, S.-H.; Thorne, R. E.
10.1101/2023.11.15.567270 — biophysics — Posted on 2023-11-17
1966 Flowtigs: safety in flow decompositions for assembly graphs
Sena, F.; Ingervo, E.; Khan, S.; Prjibelski, A.; Schmidt, S.; Tomescu, A. I.
10.1101/2023.11.17.567499 — bioinformatics — Posted on 2023-11-17
1968 Extended discrete gene regulatory network model for the Arabidopsis thaliana root-hair cell fate
Castillo-Jimenez, A.; Garay-Arroyo, A.; Sanchez-Jimenez, M. d. l. P.; Garcia-Ponce, B.; Martinez-Garcia, J. C.; Alvarez-Buylla, E. R.
10.1101/2023.11.15.567304 — systems biology — Posted on 2023-11-17
1970 Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling
Fontana, J.; Sparkman-Yager, D.; Faulkner, I.; Cardiff, R.; Kiattisewee, C.; Walls, A.; Primo, T. G.; Kinnunen, P. C.; Garcia Martin, H.; Zalatan, J. G.; Carothers, J. M.
10.1101/2023.11.17.567465 — synthetic biology — Posted on 2023-11-17
1971 A meta-analysis of rice phosphoproteomics data to understand variation in cell signalling across the rice pan-genome
Ramsbottom, K. A.; Prakash, A. A.; Perez-Riverol, Y.; Camacho, O. M.; Sun, Z.; Kundu, D.; Bowler-Barnett, E.; Martin, M.; Fan, J.; Chebotarov, D.; McNally, K.; Deutsch, E. W.; Vizcaino, J. A.; Jones, A. R.
10.1101/2023.11.17.567512 — bioinformatics — Posted on 2023-11-17
1972 The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species
Gonzalez Dalmasy, J. M.; Fitzsimmons, C.; Frye, W. J. E.; Perciaccante, A. J.; Jewell, C. P.; Jenkins, L. M.; Batista, P. J.; Robey, R. W.; Gottesman, M. M.
10.1101/2023.11.17.567538 — pharmacology and toxicology — Posted on 2023-11-17
1974 Germ fate determinants protect germ precursor cell division by restricting septin and anillin levels at the division plane
Connors, C. Q.; Mauro, M. S.; Wiles, J. T.; Countryman, A. D.; Martin, S. L.; Lacroix, B.; Shirasu-Hiza, M.; Dumont, J.; Kasza, K. E.; Davies, T. R.; Canman, J. C.
10.1101/2023.11.17.566773 — cell biology — Posted on 2023-11-17
1975 A decision-making tool to navigate through Extracellular Vesicle research and product development
Loria, F.; Picciotto, S.; Adamo, G.; Zendrini, A.; Raccosta, S.; Manno, M.; Bergese, P.; Liguori, G. L.; Bongiovanni, A.; Zarovni, N.
10.1101/2023.11.16.567368 — cell biology — Posted on 2023-11-17
1977 Chromosomal Integrons are Genetically and Functionally Isolated Units of Genomes
Blanco, P.; Trigo da Roza, F.; Toribio-Celestino, L.; Garcia-Pastor, L.; Caselli, N.; Ojeda, F.; Darracq, B.; Vergara, E.; San Millan, A.; Skovgaard, O.; Mazel, D.; Loot, C.; Escudero, J. A.
10.1101/2023.11.17.567518 — microbiology — Posted on 2023-11-17
1978 Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1
Doz-Deblauwe, E.; Bounab, B.; Carreras, F.; Silverira-Fahel, J.; Oliveira, S. C.; Lamkanfi, M.; Le Vern, Y.; GERMON, P.; Pichon, J.; Kempf, F.; Paget, C.; Remot, A.; Winter, N.
10.1101/2023.11.17.567521 — immunology — Posted on 2023-11-17
1979 PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis
Staube, J.; Bukhari, S.; Lerrer, S.; Winchester, R.; Henick, B.; Dragovich, M.; Mor, A.
10.1101/2023.11.16.566893 — immunology — Posted on 2023-11-17
1980 The Wolfram-like variant WFS1E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice.
Patergnani, S.; Bataillard, M. S.; Danese, A.; Alves, S.; Cazevieille, C.; Valero, R.; Tranebjaerg, L.; Maurice, T.; Pinton, P.; Delprat, B.; Richard, E. M.
10.1101/2023.11.16.567320 — neuroscience — Posted on 2023-11-17
1982 Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice
Brito, D. V. C.; Kupke, J.; Sokolov, R.; Cambridge, S.; Both, M.; Bengtson, C. P.; Rozov, A.; Oliveira, A. M. M.
10.1101/2023.11.17.567527 — neuroscience — Posted on 2023-11-17
1984 Engineered odorant receptors illuminate structural principles of odor discrimination
de March, C. A.; Ma, N.; Billesboelle, C. B.; Tewari, J.; del Torrent, C. L.; van der Velden, W. J.; Ojiro, I.; Takayama, I.; Faust, B.; Li, L.; Vaidehi, N.; Manglik, A.; Matsunami, H.
10.1101/2023.11.16.567230 — neuroscience — Posted on 2023-11-17
1985 Sexually dimorphic role of diet and stress on behavior, energy metabolism, and the ventromedial hypothalamus
Shetty, S.; Duesman, S. J.; Patel, S.; Huynh, P.; Shroff, S.; Das, A.; Chowhan, D.; Sebra, R.; Beaumont, K.; McAlpine, C. S.; Rajbhandari, P.; Rajbhandari, A. K.
10.1101/2023.11.17.567534 — neuroscience — Posted on 2023-11-17
1986 Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice
Kerp, H.; Gassen, J.; Grund, S. C.; Hönes, G. S.; Dörr, S.; Mittag, J.; Härting, N.; Kaiser, F.; Moeller, L. C.; Lorenz, K.; Führer, D.
10.1101/2023.11.17.567523 — physiology — Posted on 2023-11-17
1987 Virtual Tissue Expression Analysis
Simeth, J.; Hüttl, P.; Schön, M.; Nozari, Z.; Huttner, M.; Schmidt, T.; Altenbuchinger, M. C.; Spang, R.
10.1101/2023.11.16.567357 — bioinformatics — Posted on 2023-11-17
1988 A Computational Approach for Structural and Functional Analyses of Disease-associated Mutations in the Human CYLD Gene
Roy, A. S.; Feroz, T.; Islam, M. K.; Munim, M. A.; Supti, D. A.; Antora, N. J.; Reza, H. A.; Gosh, S.; Bahadur, N. M.; Alam, M. R.; Hossain, M. S.
10.1101/2023.11.16.567342 — bioinformatics — Posted on 2023-11-17
1989 rNMPID: a database for riboNucleoside Mono-Phosphates In DNA
Yang, J.; Sun, M.; Ran, Z.; Yang, T.; Kundnani, D. L.; Storici, F.; Xu, P.
10.1101/2023.11.16.567417 — bioinformatics — Posted on 2023-11-17
1997 A chromosome-level genome assembly of Solanum chilense, a tomato wild relative associated with resistance to salinity and drought
Molitor, C.; Kurowski, T.; Almeida, P. M. F.; Kevei, Z.; Spindlow, D. J.; Rose, S.; Iheanyichi, J. U.; Prasanna, H.; Thompson, A.; Mohareb, F. R.
10.1101/2023.11.17.567531 — bioinformatics — Posted on 2023-11-17
2000 NeuroVelo: interpretable learning of cellular dynamics from single-cell transcriptomic data
Kouadri Boudjelthia, I.; Milite, S.; El Kazwini, N.; Fernandez-Mateos, J.; Valeri, N.; Huang, Y.; Sottoriva, A.; Sanguinetti, G.
10.1101/2023.11.17.567500 — bioinformatics — Posted on 2023-11-17
2002 Unusual Structural Properties of Switchback DNA
Madhanagopal, B. R.; Talbot, H.; Rodriguez, A.; Louis, J. M.; Zeghal, H.; Vangaveti, S.; Reddy, K.; Chandrasekaran, A. R.
10.1101/2023.11.15.563609 — bioengineering — Posted on 2023-11-17
2003 Cortical spheroids show strain-dependent cell viability loss and neurite disruption following sustained compression injury
Gonzalez-Cruz, R. D.; Wan, Y.; Calvao, D.; Burgess, A. Z.; Renken, W. K.; Vecchio, F.; Franck, C.; Kesari, H.; Hoffman-Kim, D.
10.1101/2023.11.15.567286 — bioengineering — Posted on 2023-11-17
2006 ADEVO: Proof-of-concept of Adenovirus Directed EVOlution by random peptide display on the fiber knob
Sallard, E.; Fischer, J.; Beaude, N.; Affes, A.; Ehrke-Schulz, E.; Zhang, W.; Westhaus, A.; Cabanes-Creus, M.; Lisowski, L.; Ruszics, Z.; Ehrhardt, A.
10.1101/2023.11.16.567388 — bioengineering — Posted on 2023-11-17
2007 Viscoelastic Deformability Cytometry: Ultra-high Throughput Platform for Mechanical Phenotyping of Cells in Liquid and Solid Biopsies
Asghari, M.; Ivetich, S. D.; Aslan, M. K.; Aramesh, M.; Oleksandr, M.; Meng, Y.; Xu, R.; Colombo, M.; Weiss, T.; Balabanov, S.; Stavrakis, S.; deMello, A.
10.1101/2023.11.17.567557 — bioengineering — Posted on 2023-11-17
2008 Massively parallel mapping of substrate cleavage sites defines dipeptidyl peptidase four subsite cooperativity
Gudipati, R. K.; Gaidatzis, D.; Seebacher, J.; Muehlhaeusser, S.; Kempf, G.; Cavadini, S.; Hess, D.; Soneson, C.; Grosshans, H.
10.1101/2023.11.17.567387 — biochemistry — Posted on 2023-11-17
2011 A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone
Nookaew, I.; Xiong, J.; Onal, M.; Bustamante-Gomez, C.; Wanchai, V.; Fu, Q.; Kim, H.-N.; Almeida, M.; O'Brien, C. A.
10.1101/2023.11.17.567528 — genomics — Posted on 2023-11-17
2015 Truly the best of both worlds: merging lineage-specific and universal baiting kits to maximize phylogenomic inference
Fonseca, L. H. M.; Asselman, P.; Goodrich, K.; Nge, F.; Soule, V.; Mercier, K.; Couvreur, T. L. P.; Chatrou, L. W.
10.1101/2023.11.16.567445 — evolutionary biology — Posted on 2023-11-17
2017 Osteoblast-induced collagen alignment in a 3D in vitro bone model
Schaart, J. M.; Kea-te Lindert, M.; Roverts, R.; Sommerdijk, N.; Akiva, A.
10.1101/2023.11.17.567552 — cell biology — Posted on 2023-11-17
2018 Reversible histone deacetylase activity catalyzes lysine acylation
Tsusaka, T.; Najar, M. A.; Schwarz, B.; Bohrnsen, E.; Oses-Prieto, J. A.; Lee, C.; Burlingame, A. L.; Bosio, C. M.; Burslem, G. M.; Goldberg, E. L.
10.1101/2023.11.17.567549 — molecular biology — Posted on 2023-11-17
2020 Phenology and ecological role of Aerobic Anoxygenic Phototrophs in fresh waters
Villena-Alemany, C.; Mujakic, I.; K. Fecskeova, L.; Woodhouse, J.; Auladell, A.; Dean, J.; Hanusova, M.; Socha, M.; R. Gazulla, C.; Ruscheweyh, H.-J.; Sunagawa, S.; Kavagutti, V.; Andrei, A.-S.; Grossart, H.-P.; Ghai, R.; Koblizek, M.; Piwosz, K.
10.1101/2023.11.17.567504 — microbiology — Posted on 2023-11-17
2022 Mixed Waste Contamination Selects for a Mobile Genetic Element Population Enriched in Multiple Heavy Metal Resistance Genes
Goff, J. L.; Lui, L. M.; Nielsen, T. N.; Poole, F. L.; Smith, H. J.; Walker, K. F.; Hazen, T. C.; Fields, M. W.; Arkin, A. P.; Adams, M. W. W.
10.1101/2023.11.17.566018 — microbiology — Posted on 2023-11-17
2023 Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control
Riesenberg, B. P.; Gandy, E. J.; Kennedy, A. S.; Hunt, E. G.; Hurst, K. E.; Sedlacek, E. L.; Gao, P.; Emanuele, M. J.; Modliszewski, J.; Green, J. M.; Milner, J. J.; Wiseman, L.; Thaxton, J. E.
10.1101/2023.11.16.567431 — immunology — Posted on 2023-11-17
2024 The human Toll-like receptor 2 (TLR2) response during pathogenic Leptospira infection
Kappagoda, C.; Senavirathna, I.; Jayasundara, D.; Warnasekara, J.; Srimantha, S.; De Silva, F.; Agampodi, S.
10.1101/2023.11.16.567338 — immunology — Posted on 2023-11-17
2025 A novel non-invasive method to sample immune cells in the lower female genital tract
Peters, M. Q.; Domenjo-Vila, E.; Carlson, M.; Edlefsen, P. T.; Gasper, M.; Dabee, S.; Armistead, B.; Whidbey, C.; Jaspan, H. B.; Prlic, M.; Harrington, W. E.
10.1101/2023.11.16.567469 — immunology — Posted on 2023-11-17
2026 Macrophage Depletion Protects Against Cisplatin-Induced Ototoxicity and Nephrotoxicity
Sung, C. Y. W.; Hayase, N.; Yuen, P. S. T.; Lee, J.; Fernandez, K.; Hu, X.; Cheng, H.; Star, R. A.; Warchol, M. E.; Cunningham, L. L.
10.1101/2023.11.16.567274 — immunology — Posted on 2023-11-17
2027 VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction
Blankenship, H. E.; Carter, K. A.; Cassidy, N. T.; Markiewicz, A. N.; Thellmann, M. I.; Sharpe, A. L.; Freeman, W. M.; Beckstead, M. J.
10.1101/2023.11.16.567486 — neuroscience — Posted on 2023-11-17
2032 Vagus nerve mediated liver-brain axis is a major regulator of the metabolic landscape in the liver
Brito, C. F.; Fonseca, R. C.; Rodrigues-Ribeiro, L.; Vaz, B. F.; Tofani, G. S.; Diniz, A. B.; Fernandes, P.; Nunes, N. A.; Pessoa, R. M.; Oliveira, A. C.; Cardoso, V. N.; Fernandes, S. O.; Oliveira, M. P.; Alvarez-Leite, J.; Menezes, G. B.; Ferreira, A. V.; Gorshkov, V.; Kjeldsen, F.; Verano-Braga, T.; Oliveira, A. G.
10.1101/2023.11.16.567412 — physiology — Posted on 2023-11-17
2034 Programming Probiotics: Diet-responsive gene expression and colonization control in engineered S. boulardii
Durmusoglu, D.; Haller, D. J.; Al'Abri, I. S.; Day, K.; Sands, C.; Clark, A. S.; San Miguel, A.; Vazquez-Uribe, R.; Sommer, M. O.; Crook, N. C.
10.1101/2023.11.17.567539 — bioengineering — Posted on 2023-11-17
2035 De novo transcriptome assembly and genome annotation of the fat-tailed dunnart (Sminthopsis crassicaudata)
Ibeh, N.; Feigin, C. Y.; Frankenberg, S. R.; McCarthy, D. J.; Pask, A. J.; Gallego Romero, I.
10.1101/2023.11.16.567318 — genomics — Posted on 2023-11-17
2036 A genome sequence for the threatened whitebark pine
Neale, D. B.; Zimin, A. V.; Meltzer, A.; Bhattarai, A.; Amee, M.; Figueroa Corona, L.; Allen, B. J.; Puiu, D.; Wright, J.; De La Torre, A. R.; McGuire, P. E.; Timp, W.; Salzberg, S. L.; Wegrzyn, J. L.
10.1101/2023.11.16.567420 — genomics — Posted on 2023-11-17
2037 Chromosome Structure I: Loop extrusion or boundary:boundary pairing?
Bing, X.; Ke, W.; Fujioka, M.; Kurbidaeva, A.; Levitt, S.; Levine, M.; Schedl, P.; Jaynes, J. B.
10.1101/2023.11.17.567501 — genetics — Posted on 2023-11-17
2041 Co-habiting ants and silverfish display a converging feeding ecology
Parmentier, T.; Baltanas, R. M.; Valdivia, C.; Gaju-Ricart, M.; Boeckx, P.; Lukasik, P.; Wybouw, N.
10.1101/2023.11.17.567524 — ecology — Posted on 2023-11-17
2043 Whole organism and tissue specific analysis of pexophagy in Drosophila
Barone, F. G.; Marcello, M.; Urbe, S.; Sanchez-Soriano, N.; Clague, M. J.
10.1101/2023.11.17.567516 — cell biology — Posted on 2023-11-17
2045 DNA from non-viable bacteria biases diversity estimates in the corals Acropora loripes and Pocillopora acuta
Dungan, A. M.; Geissler, L.; Williams, A.; Gotze, C. R.; Flynn, E. C.; Blackall, L. L.; van Oppen, M. J. H.
10.1101/2023.11.16.567475 — microbiology — Posted on 2023-11-17
2054 Distinct roles of monkey OFC-subcortical pathways in adaptive behavior
Oyama, K.; Majima, K.; Nagai, Y.; Hori, Y.; Hirabayashi, T.; Eldridge, M. A. G.; Mimura, K.; Miyakawa, N.; Fujimoto, A.; Hori, Y.; Iwaoki, H.; Inoue, K.-i.; Saunders, R. C.; Takada, M.; Yahata, N.; Higuchi, M.; Richmond, B. J.; Minamimoto, T.
10.1101/2023.11.17.567492 — neuroscience — Posted on 2023-11-17
2055 The sleep quality- and myopia-linked PDE11A-Y727C variant impacts neural physiology by reducing catalytic activity and altering subcellular compartmentalization of the enzyme
Sbornova, I.; van der Sande, E.; Milosavljevic, S.; Amurrio, E.; Burbano, S. D.; Das, P.; Do, H.; Fisher, J. L.; Patel, J.; Porcher, L.; Kargbo, P.; De Zeeuw, C. I.; Meestor-Smoor, M.; Winkelman, B. H. J.; Klaver, C.; Pocivavsek, A.; Kelly, M.
10.1101/2023.11.16.567422 — neuroscience — Posted on 2023-11-17
2057 Intranasal GHK peptide enhances resilience to cognitive decline in aging mice
Tucker, M.; Keely, A.; Park, J. Y.; Rosenfeld, M.; Wezeman, J.; Mangalindan, R.; Ratner, D.; Ladiges, W. C.
10.1101/2023.11.16.567423 — neuroscience — Posted on 2023-11-17
2058 CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning
Eckenwiler, E. A.; Ingebretson, A. E.; Stolley, J. J.; Petersen, C. L.; Fusaro, M. A.; Ross, J. M.; Romportl, A. M.; Kale, E. M.; Clark, M. S.; Lemos, J. C.
10.1101/2023.11.16.567495 — neuroscience — Posted on 2023-11-17
2059 Distinct Functions for Beta and Alpha Bursts in Gating of Human Working Memory
Liljefors, J.; Almeida, R.; Rane, G.; Lundstrom, J. N.; Herman, P. A.; Lundqvist, M.
10.1101/2023.11.17.566386 — neuroscience — Posted on 2023-11-17
2061 Rapid and Highly Sensitive Detection of Fentanyl and its Analogs by a Novel Chemiluminescence Immunoassay
Zhao, J.-y.; Uddin, M.; Unsihuay, D.; Butler, W.; Xia, T. W.; Xu, J. Z.; Jannetto, P. J.; Wang, P.; Xia, X.
10.1101/2023.11.15.567298 — pharmacology and toxicology — Posted on 2023-11-17
2062 Outbreak of Highly Pathogenic Avian Influenza Virus H5N1 in Seals in the St. Lawrence Estuary, Quebec, Canada
Lair, S.; Quesnel, L.; Berhane, Y.; Delnatte, P.; Embury-Hyatt, C.; Nadeau, M.-S.; Lung, O.; Ferrell, S.
10.1101/2023.11.16.567398 — pathology — Posted on 2023-11-17
2063 An automated archival single-nucleus total RNA sequencing platform mapping integrative and retrospective cell atlas of gliomas
Wang, Y.; Xu, Z.; Chen, L.; Lin, X.; Lyu, Y.; Zhou, M.; Chen, H.; Zhang, H.; Zhang, T.; Chen, Y.; Suo, Y.; Liang, Q.; Qin, Z.
10.1101/2023.11.16.567325 — bioengineering — Posted on 2023-11-17
2064 Vascularized Liver Tissue Embedded Bioprinting Utilizing GelMA/Nanoclay-based Composite hydrogels
Tabatabaei Rezaei, N.; Dixit, K.; Kumar, H.; John, J.; Natale, G.; Park, S. S.; Kim, K.
10.1101/2023.11.16.567470 — bioengineering — Posted on 2023-11-17
2066 Comprehensive Survey of Conserved RNA Secondary Structures in Full-Genome Alignment of Hepatitis C Virus
Triebel, S.; Lamkiewicz, K.; Ontiveros, N.; Sweeney, B.; Stadler, P. F.; Petrov, A. I.; Niepmann, M.; Marz, M.
10.1101/2023.11.15.567179 — genomics — Posted on 2023-11-17
2067 Bayesian Optimized sample-specific Networks Obtained ByOmics data (BONOBO)
Saha, E.; Fanfani, V.; Mandros, P.; Ben-Guebila, M.; Fischer, J.; Shutta, K. H.; Glass, K.; DeMeo, D. L.; Lopes-Ramos, C. M.; Quackenbush, J.
10.1101/2023.11.16.567119 — genomics — Posted on 2023-11-17
2068 Simulating cell-free chromatin using preclinical models for cancer-specific biomarker discovery
De Michino, S. D.; Main, S. C.; Penny, L.; Kridel, R.; Cescon, D. W.; Hoffman, M. M.; Lupien, M.; Bratman, S. V.
10.1101/2023.11.16.567416 — genomics — Posted on 2023-11-17
2069 Genome of the North American wild apple species Malus angustifolia
Mansfeld, B. N.; Ou, S.; Burchard, E.; Yocca, A.; Harkess, A.; Gutierrez, B.; van Nocker, S.; Tang, L.; Gottschalk, C.
10.1101/2023.11.16.567428 — genomics — Posted on 2023-11-17
2070 Vaccinia virus infection induces concurrent alterations in host chromatin architecture, accessibility, and gene expression
Venu, V.; Roth, C.; Adikari, S. H.; Small, E. M.; Starkenburg, S. R.; Sanbonmatsu, K. Y.; Steadman, C. R.
10.1101/2023.11.15.567280 — genomics — Posted on 2023-11-17
2071 Astyanax mexicanus surface and cavefish chromosome-scale assemblies for trait variation discovery
Warren, W. C.; Carroll, R. A.; Haggerty, L.; Keene, A. C.; McGaugh, S. E.; Ogeh, D.; Rice, E. S.; Roback, E.; Rohner, N.; Smith, F.; X, M.
10.1101/2023.11.16.567450 — genomics — Posted on 2023-11-17
2072 Generation and characterization of a novel mouse model of Becker Muscular Dystrophy with a deletion of exons 52 to 55
Perillat, L. O. M.; Wong, T. W. Y.; Maino, E.; Ahmed, A.; Hyatt, E.; Scott, O.; Delgado Olguin, P.; Ivakine, E. A.; Cohn, R. D.
10.1101/2023.11.16.567440 — genetics — Posted on 2023-11-17
2073 Genomic analyses elucidate the causes and consequences of breakdown of distyly in Linum trigynum
Gutierrez-Valencia, J.; Zervakis, P.-I.; Postel, Z.; Fracassetti, M.; Losvik, A.; Mehrabi, S.; Bunikis, I.; Soler, L.; Hughes, P. W.; Desamore, A.; Laenen, B.; Abdelaziz, M.; Vinnere Pettersson, O.; Arroyo, J.; Slotte, T.
10.1101/2023.11.16.567348 — evolutionary biology — Posted on 2023-11-17
2079 Do aposematic species have larger range sizes? A case study with Neotropical poison frogs
Silveira, P.; Goncalves de Sousa, F.; Boning, P.; Medeiros Maciel, N.; Stropp, J.; Lotters, S.
10.1101/2023.11.16.567343 — ecology — Posted on 2023-11-17
2080 SAP expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis
Gartshteyn, Y.; Gartshteyn, Y.; Geraldino-Pardilla, L.; Bukhari, S.; Lerrer, S.; Askanase, A. D.; Mor, A.
10.1101/2023.11.16.566902 — immunology — Posted on 2023-11-17
2081 Monocyte-derived microglia with Dnmt3a mutation cause motor pathology in aging mice
Kim, J.-S.; Trzebanski, S.; Shin, S.-H.; Ilani, N. C.; Kaushansky, N.; Scheller, M.; Solomon, A.; Liu, Z.; Aust, O.; Boura-Halfon, S.; Amann, L.; Prinz, M.; Ginhoux, F.; Avraham, R.; Mueller-Tidow, C.; Uderhardt, S.; Milenkovic, I.; Shlush, L.; Jung, S.
10.1101/2023.11.16.567402 — immunology — Posted on 2023-11-17
2082 Acetyl-CoA Carboxylase Obstructs CD8+ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment
Hunt, E. G.; Hurst, K. E.; Riesenberg, B. P.; Kennedy, A. S.; Gandy, E. J.; Andrews, A. M.; Wallace, E. D.; Gao, P.; Coleman, M.; Thaxton, J. E.
10.1101/2023.11.16.567439 — immunology — Posted on 2023-11-17
2086 Lateral hypothalamic GABAergic neurons encode alcohol memories.
Alonso-Lozares, I.; Wilbers, P.; Teijsse, S.; Asperl, L.; van der Neut, C.; Schetters, D.; Van Mourik, Y.; McDonald, A. J.; Heistek, T. S.; Mansvelder, H.; De Vries, T. J.; Marchant, N. J.
10.1101/2023.11.16.567157 — neuroscience — Posted on 2023-11-17
2087 Networks extracted from nonlinear fMRI connectivity exhibit unique spatial variation and enhanced sensitivity to differences between individuals with schizophrenia and controls
Kinsey, S.; Kazimierczak, K.; Camazon, P. A.; Chen, J.; Adali, T.; Kochunov, P.; Adhikari, B.; Ford, J.; van Erp, T. G. M.; Dhamala, M.; Calhoun, V. D.; Iraji, A.
10.1101/2023.11.16.566292 — neuroscience — Posted on 2023-11-17
2088 Glia detect and mount a protective response to loss of dendrite substructure integrity in C. elegans
Varandas, K. C.; Hodges, B. M.; Lubeck, L.; Farinas, A.; Liang, Y.; Lu, Y.; Shaham, S.
10.1101/2023.11.16.567404 — neuroscience — Posted on 2023-11-17
2091 3D-Imaging of synapses in neuronal tissues with synchrotron X-ray ptychography
Bosch, C.; Diaz, A.; Holler, M.; Guizar-Sicairos, M.; Aidukas, T.; Pacureanu, A.; Mueller, E.; Peddie, C. J.; Collinson, L.; Zhang, Y.; Menzel, A.; Wanner, A.; Schaefer, A.
10.1101/2023.11.16.567403 — neuroscience — Posted on 2023-11-17
2093 The Advanced BRain Imaging on ageing and Memory (ABRIM) data collection: Study protocol and rationale
Jansen, M. G.; Zwiers, M. P.; Marques, J. P.; Chan, K.-S.; Amelink, J. S.; Altgassen, M.; Oosterman, J. M.; Norris, D. G.
10.1101/2023.11.16.567360 — neuroscience — Posted on 2023-11-17
2095 Chronic activation of a negative engram induces behavioral and cellular abnormalities
Jellinger, A. L.; Suthard, R. L.; Yuan, B.; Surets, M.; Ruesch, E. A.; Caban, A. J.; Liu, X. S.; Shpokayte, M.; Ramirez, S.
10.1101/2023.11.15.567268 — neuroscience — Posted on 2023-11-17
2097 Macromolecule modelling for improved metabolite quantification using short echo time brain 1H-MRS at 3 T and 7 T: The PRaMM Model
Dell'Orco, A.; Riemann, L. T.; Ellison, S. L. R.; Aydin, S.; Goeschel, L.; Tietze, A.; Scheel, M.; Fillmer, A.
10.1101/2023.11.16.567383 — neuroscience — Posted on 2023-11-17
2102 Guidelines for performing ribosome profiling in plants including structural analysis of rRNA fragments
Ting, M. K. Y.; Gao, Y.; Barahimipour, R.; Ghandour, R.; Liu, J.; Martinez-Seidel, F.; Smirnova, J.; Gotsmann, V. L.; Fischer, A.; Haydon, M. J.; Willmund, F.; Zoschke, R.
10.1101/2023.11.16.567332 — plant biology — Posted on 2023-11-17
2105 MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor
Nitsche, V.; Hoefner, G.; Kaiser, J.; Gertzen, C. G. W.; Seeger, T.; Niessen, K. V.; Steinritz, D.; Worek, F.; Gohlke, H.; Paintner, F. F.; Wanner, K. T.
10.1101/2023.11.15.567260 — pharmacology and toxicology — Posted on 2023-11-17
2110 Use of dye sensitizers for increased photoacoustic mechanosensation
Rafeedi, T.; Becerra, L. L.; Root, N.; Qi, B.; Fu, L.; Esparza, G.; Qie, Y.; Sasi, L.; Rouw, R.; Jokerst, J.; Lipomi, D. J.
10.1101/2023.11.15.567262 — neuroscience — Posted on 2023-11-17
2112 The meditative brain: State and trait changes in harmonic complexity for long-term mindfulness meditators
Atasoy, S.; Escrich, A.; Stark, E.; Terry, K. G. M.; Camara, E.; Sanjuan, A.; Chandaria, S.; Deco, G.; Kringelbach, M.
10.1101/2023.11.16.567347 — neuroscience — Posted on 2023-11-17
2113 Molecular determinants of antagonist interactions with chemokine receptors CCR2 and CCR5
Dawson, J. R. D.; Wadman, G. M.; Zhang, P.; Gu, S.; Shroka, T.; Borrega-Roman, L.; Salanga, C.; Handel, T. M.; Kufareva, I.
10.1101/2023.11.15.567150 — pharmacology and toxicology — Posted on 2023-11-17
2114 Reduction of coastal lighting decreases seabird strandings
Burt, T. V.; Collins, S. M.; Green, S.; Doiron, P. B.; Wilhelm, S. I.; Montevecchi, W. A.
10.1101/2023.11.15.567317 — animal behavior and cognition — Posted on 2023-11-17
2117 Hot springs viruses at Yellowstone National Park have ancient origins and are adapted to their thermophilic hosts.
Benites, L. F.; Stephens, T. G.; Van Etten, J.; James, T.; Christian, W. C.; Barry, K.; Grigoriev, I. V.; McDermott, T. R.; Bhattacharya, D.
10.1101/2023.11.15.567249 — evolutionary biology — Posted on 2023-11-17
2120 Invasive traits of freshwater fish database (ITOFF)
Jessop, A.; Michalopoulou, A.; Coonan, C.; Mazzei, L.; Sutherland O'Brien, E.; Brady, G.; Davison, C.; Gourlay, W.; Henderson, E.; Lornie, A.; McCloskey, E.; Ramsay, H.; Wilson, S.; Shimadzu, H.; Barbosa, M.
10.1101/2023.11.15.567195 — ecology — Posted on 2023-11-17
2121 mRNA Vaccines Encoding Influenza Virus Hemagglutinin (HA) Elicits Immunity in Mice from Influenza A Virus Challenge
Reneer, Z. B.; Bergeron, H. C.; Reynolds, S.; Thornhill-Wadolowski, E.; Feng, L.; Bugno, M.; Truax, A. D.; Tripp, R. A.
10.1101/2023.11.15.566914 — immunology — Posted on 2023-11-17
2124 Pain persists in mice lacking both Substance P and CGRPα signaling
MacDonald, D. I.; Jayabalan, M.; Seaman, J. T.; Nickolls, A. R.; Chesler, A. T.
10.1101/2023.11.15.567208 — neuroscience — Posted on 2023-11-17
2125 Theoretical Analysis of Divalent Cation Effects on Aptamer Recognition of Neurotransmitter Targets
Douaki, A.; Stuber, A.; Hengsteler, J.; Momotenko, D.; Rogers, D. M.; Rocchia, W.; Hirst, J. D.; Nakatsuka, N.; garoli, D.
10.1101/2023.11.15.567205 — neuroscience — Posted on 2023-11-17
2126 Molecular organization of autonomic, respiratory, and spinally-projecting neurons in the mouse ventrolateral medulla
Schwalbe, D. C.; Stornetta, D. S.; Abraham-Fan, R.-J.; Souza, G. M. P. R.; Jalil, M.; Crook, M. E.; Campbell, J. N.; Abbott, S. B. G.
10.1101/2023.11.15.564801 — neuroscience — Posted on 2023-11-17
2130 Visual interpretability of image-based classification models by generative latent space disentanglement applied to in vitro fertilization
Rotem, O.; Schwartz, T.; Maor, R.; Tauber, Y.; Tsarfati Shapiro, M.; Meseguer, M.; Gilboa, D.; Seidman, D. S.; Zaritsky, A.
10.1101/2023.11.15.566968 — systems biology — Posted on 2023-11-17
2132 Bacterial assembly in the switchgrass rhizosphere is shaped by phylogeny, host genotype, and growing site.
Sutherland, J.; Bell, T. H.; Bonos, S.; Tkach, C.; Hansen, J.; Crawford, R.; Carlson, J. E.; Lasky, J. R.
10.1101/2023.11.15.567221 — plant biology — Posted on 2023-11-17
2133 The histone modifier KAT2A presents a selective target in a subset of well-differentiated microsatellite-stable colorectal cancers
Kufrin, V.; Seiler, A.; Brilloff, S.; Rothfuss, H.; Schuster, S.; Schaefer, S.; Rahimian, E.; Baumgarten, J.; Ball, C. R.; Bornhaeuser, M.; Glimm, H.; Bill, M.; Wurm, A. A.
10.1101/2023.11.15.567034 — cancer biology — Posted on 2023-11-17
2134 EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism
Olmedo-Pelayo, J.; Granado-Calle, E. L.; Delgado-Bellido, D.; Lobo-Selma, L.; Jordan-Perez, C.; Monteiro-Amaral, A. T.; Ehlers, A. C.; Ohmura, S.; Carcaboso, A. M.; Alonso, J.; Machado, I.; Llombart-Bosch, A.; Grunewald, T. G. P.; Gomez-Herreros, F.; de Alava, E.
10.1101/2023.05.30.542894 — cancer biology — Posted on 2023-11-17
2135 Decoil: Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data
Giurgiu, M.; Wittstruck, N.; Rodriguez-Fos, E.; Chamorro Gonzalez, R.; Bruckner, L.; Krienelke-Szymansky, A.; Helmsauer, K.; Hartebrodt, A.; Koche, R. P.; Haase, K.; Reinert, K.; Henssen, A. G.
10.1101/2023.11.15.567169 — cancer biology — Posted on 2023-11-17
2136 Androgen receptor signaling blockade enhances NK cell-mediated killing of prostate cancer cells and sensitivity to NK cell checkpoint blockade
Pinho-Schwermann, M.; Carneiro, B. A.; Carlsen, L.; Huntington, K. E.; Srinivasan, P. R.; George, A.; Tajiknia, V.; MacDonald, W.; Purcell, C.; Zhou, L.; De Souza, A.; Safran, H. P.; El-Deiry, W. S.
10.1101/2023.11.15.567201 — cancer biology — Posted on 2023-11-17
2137 MYC-NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
Patterson, S. D.; Massett, M. E.; Huang, X.; Jorgensen, H. G.; Michie, A. M.
10.1101/2023.11.15.567209 — cancer biology — Posted on 2023-11-17
2141 A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution
Nardone, S.; De Luca, R.; Zito, A.; Klymko, N.; Nicoloutsopoulos, D.; Amsalem, O.; Brannigan, C.; Resch, J. M.; Jacobs, C. L.; Pant, D.; Veregge, M.; Srinivasan, H.; Grippo, R. M.; Yang, Z.; Zeidel, M. L.; Andermann, M. L.; Harris, K. D.; Tsai, L. T.; Arrigoni, E.; Verstegen, A. M. J.; Saper, C. B.; Lowell, B. B.
10.1101/2023.09.18.558047 — neuroscience — Posted on 2023-11-17
2143 A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice
Medeiros, D.; Ayala-Baylon, K.; Egido-Betancourt, H.; Miller, E.; Chapleau, C. A.; Robinson, H. A.; Phillips, M. L.; Yang, T.; Longo, F.; Li, W.; Pozzo-Miller, L.
10.1101/2023.11.09.566435 — neuroscience — Posted on 2023-11-17
2144 From CFTR to a CF signalling network: a systems biology approach to study Cystic fibrosis
Najm, M.; MARTIGNETTI, L.; Cornet, M.; Kelly-Aubert, M.; Sermet-Gaudelus, I.; Calzone, L.; STOVEN, V.
10.1101/2023.11.15.567166 — systems biology — Posted on 2023-11-17
2145 Physcomitrium patens SMXL homologs are PpMAX2-dependent negative regulators of growth
Guillory, A.; Lopez-Obando, M.; Bouchenine, K.; Lambret, L.; Le Bris, P.; Lecureuil, A.; Pillot, J.-P.; Steinmetz, V.; Boyer, F.-D.; Rameau, C.; de Saint Germain, A.; Bonhomme, S.
10.1101/2023.04.11.536386 — plant biology — Posted on 2023-11-17
2149 Evidence that recent climatic changes have expanded the potential geographic range of the Mediterranean fruit fly
Szyniszewska, A. M.; Bieszczak, H.; Kozyra, K.; Papadopoulos, N. T.; De Meyer, M.; Nowosad, J.; Ota, N.; Kriticos, D. J.
10.1101/2023.11.15.566983 — ecology — Posted on 2023-11-17
2151 Fast evolution of SARS-CoV-2 BA.2.86 to JN.1 under heavy immune pressure
Yang, S.; Yu, Y.; Xu, Y.; Jian, F.; Song, W.; Yisimayi, A.; Wang, P.; Wang, J.; Liu, J.; Yu, L.; Niu, X.; Wang, J.; Wang, Y.; Shao, F.; Jin, R.; Wang, Y.; Cao, Y.
10.1101/2023.11.13.566860 — immunology — Posted on 2023-11-17
2152 Single-B cell analysis correlates high-lactate secretion with stress and increased apoptosis
Bucheli, O. T. M.; Rodrigues, D.; Portmann, K.; Linder, A.; Thoma, M.; Halin, C.; Eyer, K.
10.1101/2023.09.01.555863 — immunology — Posted on 2023-11-17
2154 Stress resilience is an active and multifactorial process manifested by structural, functional, and molecular changes in synapses
Baczynska, E.; Zareba-Koziol, M.; Ruszczycki, B.; Krzystyniak, A.; Wojtowicz, T.; Bijata, K.; Pochwat, B.; Magnowska, M.; Roszkowska, M.; Figiel, I.; Masternak, J.; Pytys, A.; Dzwonek, J.; Worch, R.; Olszynski, K. H.; Wardak, A. D.; Szymczak, P.; Labus, J.; Radwanska, K.; Jaholkowski, P.; Hogendorf, A.; Ponimaskin, E.; Filipkowski, R. K.; Szewczyk, B.; Bijata, M.; Wlodarczyk, J.
10.1101/2022.05.19.492644 — neuroscience — Posted on 2023-11-17
2155 A Myelin Map of Trunk Folds in the Elephant Trigeminal Nucleus
Reveyaz, N.; Schneeweiss, U.; Heise, O.; Gerhardt, B.; Gui, A. M.; Kaufmann, L. V.; Alfken, J.; Reichmann, J.; Salditt, T.; Hildebrandt, T. B.; Brecht, M.
10.1101/2023.11.15.567239 — neuroscience — Posted on 2023-11-17
2159 Point mutations in Arf1 reveal cooperative effects of the N-terminal region and myristate for GTPase-activating protein catalytic activity
Rosenberg, E.; Jian, X.; Soubias, O.; Jackson, R.; Gladu, E.; Andersen, E.; Esser, L.; Sodt, A.; Xia, D.; Byrd, R. A.; Randazzo, P. A.
10.1101/2023.11.15.567322 — biochemistry — Posted on 2023-11-17
2161 Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
Bai, Y.; Morita, K.; Kokaji, T.; Hatano, A.; Ohno, S.; Egami, R.; Pan, Y.; Li, D.; Yugi, K.; Uematsu, S.; Inoue, H.; Inaba, Y.; Suzuki, Y.; Matsumoto, M.; Takahashi, M.; Yoshihiro, I.; Bamba, T.; Hirayama, A.; Soga, T.; Kuroda, S.
10.1101/2023.11.15.567316 — systems biology — Posted on 2023-11-17
2163 Snowball: a novel gene family required for developmental patterning in fruiting bodies of mushroom-forming fungi (Agaricomycetes)
Földi, C.; Merenyi, Z.; Balint, B.; Csernetics, A.; Miklovics, N.; Wu, H.; Hegedüs, B.; Viragh, M.; Hou, Z.; Liu, X.-B.; Galgoczy, L.; Nagy, L.
10.1101/2023.11.13.566867 — developmental biology — Posted on 2023-11-17
2164 Isolation and expansion of pure and functional γδ T cells
Verkerk, T.; Pappot, A. T.; Jorritsma, T.; King, L. A.; Spaapen, R. M.; van Ham, S. M.
10.1101/2023.11.12.566762 — immunology — Posted on 2023-11-17
2165 Comparing virtual staining artificial intelligence model performance on same-tissue versus serial-tissue sections based on CD3+ T-cell ground truth
Azam, A. B.; Wee, F.; Väyrynen, J.; Lim, W. W.-Y.; Xue, Y.; Chua, B. L.; Lim, J.; Tan, D.; Takano, A.; Chow, C. Y.; Khor, L. Y.; Lim, T.; Yeong, J.; Lau, M. C.; Cai, Y.
10.1101/2023.11.12.565422 — immunology — Posted on 2023-11-17
2166 The role of BST4 in the pyrenoid of Chlamydomonas reinhardtii
Adler, L.; Lau, C. S.; Shaikh, K. M.; Maldegem, K. v.; Payne-Dwyer, A. L.; Lefoulon, C.; Girr, P.; Atkinson, N.; Barrett, J.; Emrich-Mills, T. Z.; Dukic, E.; Blatt, M. R.; Leake, M.; Peltier, G.; Spetea, C.; McCormick, A. J.; Mackinder, L. C.; Walker, C. E.
10.1101/2023.06.15.545204 — plant biology — Posted on 2023-11-17
2167 A multiscale approach to investigate fluorescence and NDVI imaging as proxy of photosynthetic traits in wheat
Virlet, N.; Pennacchi, J. P.; Sadeghi-Tehran, P.; Ashfield, T.; Orr, D.; Carmo-Silva, E.; Hawkesford, M.
10.1101/2023.11.10.566533 — plant biology — Posted on 2023-11-17
2169 Neuronal Synchrony and Critical Bistability: Mechanistic Biomarkers for Localizing the Epileptogenic Network
Wang, S. H.; Arnulfo, G.; Nobili, L.; Myrov, V.; Ferrari, P.; Ciuciu, P.; Palva, S.; Palva, J. M.
10.1101/2023.05.21.541570 — physiology — Posted on 2023-11-17
2171 YY2/BUB3 axis-mediated SAC hyperactivity determines tumor cell fate through chromosomal instability
Hosea, R.; Duan, W.; Meliala, I. T. S.; Li, W.; Wei, M.; Hillary, S.; Zhao, H.; Miyagishi, M.; Wu, S.; Kasim, V.
10.1101/2023.10.07.561167 — cancer biology — Posted on 2023-11-17
2173 Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2
Weeratunga, S.; Gormal, R.; Liu, M.; Eldershaw, D.; Livingstone, E.; Malapaka, A.; Wallis, T.; Bademosi, A.; Jiang, A.; Healy, M.; Meunier, F.; Collins, B.
10.1101/2023.02.20.529329 — biochemistry — Posted on 2023-11-17
2174 Spring reproductive success influences autumnal malarial load in a passerine bird
Pigeault, R.; Cozzarolo, C.-S.; Wassef, J.; Gremion, J.; Bastardot, M.; Glaizot, O.; Christe, P.
10.1101/2023.07.28.550923 — ecology — Posted on 2023-11-17
2179 The Uniqueness of Human Vulnerability to Brain Aging in Great Ape Evolution
Vickery, S.; Patil, K. R.; Dahnke, R.; Hopkins, W. D.; Sherwood, C. C.; Caspers, S.; Eickhoff, S. B.; Hoffstaedter, F.
10.1101/2022.09.27.509685 — neuroscience — Posted on 2023-11-17
2181 Accelerating protein engineering with fitness landscape modeling and reinforcement learning
Sun, H.; He, L.; Deng, P.; Liu, G.; Liu, H.; Cao, C.; Ju, F.; Wu, L.; Qin, T.; Liu, T.-Y.
10.1101/2023.11.16.565910 — synthetic biology — Posted on 2023-11-17
2182 NBR1-mediated selective autophagy of ARF7 modulates root branching
Ebstrup, E.; Ansboel, J.; Garcia, A. P.; Culp, H.; Chevalier, J.; Clemmens, P.; Coll, N. S.; Moreno-Risueno, M. A.; Rodriguez, E.
10.1101/2022.08.19.504407 — plant biology — Posted on 2023-11-17
2184 Simulations of sequence evolution: how (un)realistic they are and why
Trost, J.; Haag, J.; Hoehler, D.; Jacob, L.; Stamatakis, A.; Boussau, B.
10.1101/2023.07.11.548509 — bioinformatics — Posted on 2023-11-17
2185 Unraveling Neuronal Identities Using SIMS: A Deep Learning Label Transfer Tool for Single-Cell RNA Sequencing Analysis
Gonzalez-Ferrer, J.; Lehrer, J.; O'Farrell, A.; Paten, B.; Teodorescu, M.; Haussler, D.; Jonsson, V. D.; Mostajo-Radji, M. A.
10.1101/2023.02.28.529615 — bioinformatics — Posted on 2023-11-17
2188 Genetically encoded affinity reagents (GEARs): A toolkit for visualizing and manipulating endogenous protein function in vivo.
Boswell, C. W.; Hoppe, C.; Sherrard, A.; Miao, L.; Kojima, M. L.; Krishna, S.; Musaev, D.; Zhao, N.; Stasevich, T. J.; Giraldez, A. J.
10.1101/2023.11.15.567075 — developmental biology — Posted on 2023-11-17
2189 Functional Screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair
Perez-Bermejo, J. A.; Efagene, O.; Matern, W. M.; Holden, J. K.; Kabir, S.; Chew, G. M.; Andreoletti, G.; Catton, E.; Ennis, C. L.; Garcia, A.; Gerstenberg, T. L.; Hill, K. A.; Jain, A.; Krassovski, K.; Lalisan, C. D.; Lord, D.; Quejarro, B. J.; Sales-Lee, J.; Shah, M.; Silva, B. J.; Skowronski, J.; Strukov, Y. G.; Thomas, J.; Veraz, M.; Vijay, T.; Wallace, K. A.; Yuan, Y.; Grogan, J. L.; Wienert, B.; Lahiri, P.; Treusch, S.; Dever, D. P.; Soros, V. B.; Partridge, J. R.; Seim, K. L.
10.1101/2023.11.16.567426 — molecular biology — Posted on 2023-11-16
2190 Accelerating protein engineering with fitness landscape modeling and reinforcement learning
Sun, H.; He, L.; Deng, P.; Liu, G.; Liu, H.; Cao, C.; Ju, F.; Wu, L.; Qin, T.; Liu, T.-Y.
10.1101/2023.11.16.565910 — synthetic biology — Posted on 2023-11-16
2191 De novo Design of Peptides that Bind Specific Conformers of α-Synuclein
Wallace, H.; Yang, H.; Tan, S. K.; Pan, H.; Yang, R.; Xu, J.; Jo, H.; Condello, C.; Polizzi, N.; DeGrado, W.
10.1101/2023.11.14.567090 — biophysics — Posted on 2023-11-16
2195 Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata
Warner, J. F.; Besemer, R.; Schickle, A.; Changsut, I. V.; Borbee, E.; Sharp, K.; Babonis, L. S.
10.1101/2023.11.16.567385 — developmental biology — Posted on 2023-11-17
2196 Comprehensive mapping of sensory and sympathetic innervation of the developing kidney
N'Guetta, P.-E. Y.; McLarnon, S. R.; Tassou, A.; Geron, M.; Scherrer, G.; O'Brien, L. L.
10.1101/2023.11.15.567276 — developmental biology — Posted on 2023-11-17
2198 Video Diffusion models for the apoptosis forcasting
AWASTHI, A.; Nizam, J.; Zare, S.; Ahmad, S.; Montalvo, M. J.; Varadarajan, N.; Roysam, B.; Nguyen, H. V.
10.1101/2023.11.16.567461 — cell biology — Posted on 2023-11-17
2202 Neutrophil motility is regulated by both cell intrinsic and endothelial cell ARPC1B
Peterson, A. N.; Bennin, D.; Lasarev, M.; Chini, J.; Beebe, D. J.; Huttenlocher, A.
10.1101/2023.11.16.567429 — cell biology — Posted on 2023-11-17
2203 Abnormal white matter development during early childhood in autism and developmental disability
Liu, Y.; Zhang, J.; Rolls, E.; Dai, Y.; Geng, S.; Deng, L.; Chen, Z.; Zhang, Y.; Tao, M.; Zhang, L.; Ren, T.; Feng, J.; Cao, M.; Li, F.
10.1101/2023.11.15.567183 — neuroscience — Posted on 2023-11-16
2209 New sensitive tools to characterize meta-metabolome response to short- and long-term cobalt exposure in dynamic river biofilm communities
Colas, S.; Marie, B.; Morin, S.; Milhe-Poutingon, M.; Foucault, P.; Chalvin, S.; Gelber, C.; Baldoni-Andrey, P.; Gurieff, N.; Fortin, C.; Le Faucheur, S.
10.1101/2023.11.16.567369 — molecular biology — Posted on 2023-11-16
2210 Identification of a putative rhamnogalacturonan-II CMP-beta-Kdo transferase through a callus-based gene editing method which overcomes embryo lethality.
Zhang, Y.; Sharma, D.; Liang, Y.; Downs, N.; Dolman, F.; Thorne, K.; Pereira, J. H.; Adams, P. D.; Scheller, H.; O'Neill, M.; Urbanowicz, B. R.; Mortimer, J. C.
10.1101/2023.11.15.567147 — plant biology — Posted on 2023-11-16
2214 Ultrasensitive allele inference from immune repertoire sequencing data with MiXCR
Mikelov, A.; Nefedev, G.; Tashkeev, A.; Rodriguez, O. L.; Ortmans, D. A.; Skatova, V.; Izraelson, M.; Davydov, A.; Poslavsky, S.; Rahmouni, S.; Watson, C. T.; Chudakov, D.; Boyd, S. D.; Bolotin, D. A.
10.1101/2023.10.10.561703 — immunology — Posted on 2023-11-16
2215 Extracellular Matrix Abnormalities Contribute to Cardiac Insulin Resistance and Associated Dysfunction in Diet-induced Obese Mice
Musale, V.; Murdoch, C.; Banah, A. K.; Hasib, A.; Hennayake, C. K.; Dong, B.; Lang, C. C.; Wasserman, D. H.; Kang, L.
10.1101/2023.11.14.567128 — physiology — Posted on 2023-11-16
2216 Septin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function.
De Gasperi, R.; Csernoch, L.; Dienes, B.; Gonczi, M.; Chakrabarty, J. K.; Goeta, S.; Aslan, A.; Toro, C. A.; Karasik, D.; Brown, L. M.; Brotto, M.; Cardozo, C. P.
10.1101/2023.05.11.540467 — physiology — Posted on 2023-11-16
2221 Integrative multiomics analysis of neointima proliferation in human saphenous vein: implications for bypass graft disease
Kim, D.; Goo, B.; Shi, H.; Coffey, P.; Veerapaneni, P.; Chouhaita, R.; Cyriac, N.; Aboud, G.; Cave, S.; Greenway, J.; Mundkur, R.; Ahmadieh, S.; Harb, R.; Ogbi, M.; Fulton, D. J.; Huo, Y.; Zhang, W.; Long, X.; Miano, J. M.; Guha, A.; Kim, H. W.; Shi, Y.; Rice, R. D.; Gallo, D. R.; Patel, V.; Lee, R.; Weintraub, N. L.
10.1101/2023.11.14.567053 — genomics — Posted on 2023-11-16
2223 Small in size but huge as reservoir -- insights into the virome of European white-toothed shrews
Haring, V. C.; Litz, B.; Jacob, J.; Brecht, M.; Bauswein, M.; Sehl-Ewert, J.; Heroldova, M.; Hoffmann, D.; Ulrich, R. G.; Beer, M.; Pfaff, F.
10.1101/2023.11.14.567014 — evolutionary biology — Posted on 2023-11-16
2228 The embryonic DNA methylation program modulates the cis-regulatory landscape via CTCF antagonism
Monteagudo-Sanchez, A.; Richard Albert, J.; Scarpa, M.; Noordermeer, D.; Greenberg, M. V. C.
10.1101/2023.11.16.567349 — molecular biology — Posted on 2023-11-16
2229 Homologs of the plastidal preprotein translocase Tic20 mediate organelle assembly in bacteria
Paulus, A.; Ahrens, F.; Schraut, A.; Hofman, H.; Schiller, T.; Sura, T.; Becher, D.; Uebe, R.
10.1101/2023.11.16.567405 — microbiology — Posted on 2023-11-16
2230 Investigating the Association Between Nitrate Dosing and Nitrite Generation by the Human Oral Microbiota in Continuous Culture
Willmott, T.; Serrage, H.; Cottrell, E. C.; Humphreys, G. J.; Myers, J.; Campbell, P. M.; McBain, A. J.
10.1101/2023.11.15.567236 — microbiology — Posted on 2023-11-16
2231 Fecal microbiota transplantation (FMT) from healthy and bipolar donors elicits distinct emotional behaviors and gut-brain metabolite profiles in mice
Bukowski-Thall, G.; Fellendorf, F.; Gorkiewicz, S.; Ip, K. C. K.; Schmidt, L.; Durdevic, M.; Fabisch, H.; Mörkl, S.; Wagner-Skacel, J.; Bengesser, S.; Lenger, M.; Dalkner, N.; Gorkiewicz, G.; Högenauer, C.; Madl, T.; Moissl-Eichinger, C.; Farzi, A.; Reininghaus, E.
10.1101/2023.11.16.566698 — microbiology — Posted on 2023-11-16
2232 Evolution of a small phage protein confers resistance to antiphage defense in Enterococcus faecalis
Johnson, C. N.; Bullen, N. P.; Andersen, S. E.; Arya, G.; Marotta, S. R.; Whitney, J. C.; Duerkop, B. A.
10.1101/2023.11.16.567456 — microbiology — Posted on 2023-11-16
2234 Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Semenova, L.; Wang, Y.; Falcinelli, S. D.; Archin, N.; Cooper-Volkheimer, A. D.; Goonetilleke, N.; Murdoch, D. M.; Rudin, C. D.; Margolis, D. M.; Browne, E. P.
10.1101/2023.11.16.567386 — microbiology — Posted on 2023-11-16
2235 Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase producing Enterobacterales
Graf, F. E.; Goodman, R. N.; Gallichan, S.; Forrest, S.; Picton-Barlow, E.; Fraser, A. J.; Phan, M.-D.; Mphasa, M.; Hubbard, A. T.; Musicha, P.; Schembri, M. A.; Roberts, A. P.; Edwards, T.; Lewis, J. M.; Feasey, N. A.
10.1101/2023.11.16.567242 — microbiology — Posted on 2023-11-16
2237 Fast evolution of SARS-CoV-2 BA.2.86 to JN.1 under heavy immune pressure
Cao, Y.; Yang, S.; Yu, Y.; Xu, Y.; Jian, F.; Song, W.; Yisimayi, A.; Wang, P.; Wang, J.; Liu, J.; Yu, L.; Niu, X.; Wang, J.; Wang, Y.; Shao, F.; Jin, R.; Wang, Y.
10.1101/2023.11.13.566860 — immunology — Posted on 2023-11-16
2240 Flow-field inference from neural data using deep recurrent networks
Kim, T. D.; Luo, T. Z.; Can, T.; Krishnamurthy, K.; Pillow, J. W.; Brody, C. D.
10.1101/2023.11.14.567136 — neuroscience — Posted on 2023-11-16
2241 The neurons that drive infradian sleep-wake and mania-like behavioral rhythms
Markam, P. S.; Bourguignon, C.; Zhu, L.; Darvas, M.; Sabatini, P. V.; Kokoeva, M. V.; GIROS, B.; Storch, K.-F.
10.1101/2023.11.14.566955 — neuroscience — Posted on 2023-11-16
2243 Leukemia in Sprague-Dawley Rats Exposed Long-term from Prenatal Life to Glyphosate and Glyphosate-Based Herbicides
Panzacchi, S.; Tibaldi, E.; De Angelis, L.; Falcioni, L.; Gnudi, F.; Iuliani, M.; Manservigi, M.; Manservisi, F.; Manzoli, I.; Menghetti, I.; Montella, R.; Noferini, R.; Sgargi, D.; Strollo, V.; Antoniou, M.; Chen, J.; Dinelli, G.; Lorenzetti, S.; Mesnage, R.; Vornoli, A.; Perry, M. J.; Landrigan, P. J.; Belpoggi, F.; Mandrioli, D.
10.1101/2023.11.14.566013 — pharmacology and toxicology — Posted on 2023-11-16
2244 TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma
Tian, M.; Yang, L.; Zhao, Z.; Li, J.; Wang, L.; Yin, Q.; Hu, W.; Lou, Y.; Du, J.; Zhao, P.
10.1101/2023.11.14.567124 — cancer biology — Posted on 2023-11-16
2245 Proteomic characterisation of Sarculator nomogram-defined risk groups in soft tissue sarcomas of the extremities and trunk wall
Chadha, M.; Iadecola, S.; Jenks, A.; Burns, J.; Arthur, A.; Pankova, V.; Wilding, C.; Callegaro, D.; Strauss, D.; Thway, K.; Gronchi, A.; Jones, R.; Miceli, R.; Pasquali, S.; Huang, P. H.
10.1101/2023.11.14.567122 — cancer biology — Posted on 2023-11-16
2247 YAP localization mediates mechanical adaptation of human cancer cells during extravasation in vivo
So, W. Y.; Wong, C. S.; Azubuike, U. F.; Paul, C. D.; Sangsari, P. R.; Gordon, P. B.; Gong, H.; Maity, T. K.; Lim, P.; Yang, Z.; Haryanto, C. A.; Batchelor, E.; Jenkins, L. M.; Morgan, N. Y.; Tanner, K.
10.1101/2023.11.14.567015 — biophysics — Posted on 2023-11-16
2248 Raman microscopy of cryofixed biological specimens for high-resolution and high-sensitivity chemical imaging
Mizushima, K.; Kumamoto, Y.; Tamura, S.; Yamanaka, M.; Mochizuki, K.; Li, M.; Egoshi, S.; Dodo, K.; Harada, Y.; Smith, N. I.; Sodeoka, M.; Tanaka, H.; Fujita, K.
10.1101/2023.11.15.567077 — biophysics — Posted on 2023-11-16
2256 Implantable nanophotonic neural probes for integrated patterned photostimulation and electrophysiology recording
Chen, F. D.; Chameh, H. M.; Movahed, M.; Wahn, H.; Mu, X.; Ding, P.; Xue, T.; Straguzzi, J. N.; Roszko, D. A.; Sharma, A.; Govdeli, A.; Jung, Y.; Chua, H.; Lu, X.; Lo, P. G. Q.; Valiante, T. A.; Sacher, W. D.; Poon, J. K. S.
10.1101/2023.11.14.567101 — bioengineering — Posted on 2023-11-16
2259 A yeast two-hybrid system to obtain triple-helical ligands from combinatorial random peptide libraries
Masuda, R.; Thant, K. P. P.; Kawahara, K.; Oki, H.; Kadonosono, T.; Kobayashi, Y.; Koide, T.
10.1101/2023.11.14.567114 — biochemistry — Posted on 2023-11-16
2260 Bioinformatic, enzymatic and structural characterization of Trichuris suis hexosaminidase HEX-2
Dutkiewicz, Z.; Varrot, A.; Breese, K. J.; Stubbs, K. A.; Nuschy, L.; Adduci, I.; Paschinger, K.; Wilson, I. B. H.
10.1101/2023.11.15.567194 — biochemistry — Posted on 2023-11-16
2265 Progression of herpesvirus infection remodels mitochondrial organization and metabolism
Leclerc, S.; Gupta, A.; Ruokolainen, V.; Chen, J.-H.; Kunnas, K.; Ekman, A.; Niskanen, H.; Belevich, I.; Vihinen, H.; Turkki, P.; Perez-Berna, A.; Kapishnikov, S.; Mäntylä, E.; Harkiolaki, M.; Dufour, E.; Hytönen, V.; Pereiro, E.; McEnroe, T.; Fahy, K.; Kaikkonen, M. U.; Jokitalo, E.; Larabell, C. A.; Venera Weinhardt, V.; Mattola, S.; Aho, V.; Vihinen-Ranta, M.
10.1101/2023.11.16.567337 — microbiology — Posted on 2023-11-16
2270 A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides
Zohaib Ali, M.; Dutt, T. S.; MacNeil, A.; Walz, A.; Patterson, J.; Pearce, C.; Lam, H.; Lee, R.; Liu, J.; Robertson, G. T.; Hickey, A. J.; Meibohm, B.; Gonzalez-Juarrero, M.
10.1101/2023.11.16.567434 — microbiology — Posted on 2023-11-16
2271 Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy.
Lee, J. S.; Dittmar, M.; Miller, J.; Li, M.; Ayyanathan, K.; Ferretti, M. B.; Hulahan, J.; Whig, K.; Etwebi, Z.; Griesman, T.; Schultz, D. C.; Cherry, S.
10.1101/2023.11.13.566859 — microbiology — Posted on 2023-11-16
2274 Viral infection disrupts intestinal homeostasis via Sting-dependent NF-kB signaling
Nigg, J. C.; Blanc, H.; Frangeul, L.; Mongelli, V.; Godron, X.; Bardin, A. J.; Saleh, M.-C.
10.1101/2023.11.16.567400 — microbiology — Posted on 2023-11-16
2275 Single phage proteins sequester TIR- and cGAS-generated signaling molecules
Li, D.; Xiao, Y.; Xiong, W.; Fedorova, I.; Wang, Y.; Liu, X.; Huiting, E.; Ren, J.; Gao, Z.; Zhao, X.; Cao, X.; Zhang, Y.; Bondy-Denomy, J.; Feng, Y.
10.1101/2023.11.15.567273 — microbiology — Posted on 2023-11-16
2276 Diving into bacterial dormancy: emergence of osmotically stable wall-less forms in an aquatic environment
Carvalho, F.; Carreaux, A.; Sartori-Rupp, A.; Tachon, S.; Gazi, A. D.; Courtin, P.; Nicolas, P.; Dubois-Brissonnet, F.; Barbotin, A.; Desgranges, E.; Gloux, K.; Schouler, C.; Carballido-Lopez, R.; Chapot-Chartier, M.-P.; Milohanic, E.; Bierne, H.; Pagliuso, A.
10.1101/2023.11.16.566987 — microbiology — Posted on 2023-11-16
2279 The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection
Melton, A.; Rowe, L. A.; Penney, T.; Krzykwa, C.; Goff, K.; Scheuermann, S. E.; Melton, H. J.; Williams, K.; Golden, N.; Moore Green, K.; Smith, B.; Russell-Lodrigue, K.; Dufour, J. P.; Doyle-Meyers, L. A.; Schiro, F.; Aye, P. P.; Lifson, J. D.; Beddingfield, B. J.; Blair, R. V.; Bohm, R. P.; Kolls, J. K.; Rappaport, J.; Hoxie, J. A.; Maness, N. J.
10.1101/2023.11.15.567132 — immunology — Posted on 2023-11-16
2280 Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females
Babey, M. E.; Krause, W. C.; Herber, C. B.; Chen, K.; Nikkannen, J.; Rodriquez, R.; Zhang, X.; Castro-Navarro, F.; Wang, Y.; Villeda, S.; Lane, N. E.; Scheller, E. L.; Chan, C. K. F.; Ambrosi, T. H.; Ingraham, H. A.
10.1101/2023.08.28.554707 — neuroscience — Posted on 2023-11-16
2282 Reproducible Neuronal Components found using Group Independent Component Analysis in Resting State Electroencephalographic Data
Ochoa-Gomez, J. F.; Mantilla Ramos, Y. J.; Henao Isaza, V.; Tobon, C. A.; Lopera, F.; Aguillon, D.; Suarez Revelo, J. X.
10.1101/2023.11.14.566952 — neuroscience — Posted on 2023-11-16
2283 Simultaneously-recorded cholinergic axons and cortical acetylcholine are highly correlated with pupil size and locomotion under spontaneous conditions
Neyhart, E.; Zhou, N.; Munn, B. R.; Law, R. G.; Smith, C.; Mridha, Z. H.; Blanco, F. A.; Li, G.; Li, Y.; McGinley, M. J.; Shine, J. M.; Reimer, J.
10.1101/2023.11.14.567116 — neuroscience — Posted on 2023-11-16
2284 Gray matter volume in women with the BRCA mutation with and without ovarian removal
Witt, S. T.; Brown, A.; Gravelsins, L.; Engström, M.; Classon, E.; Lykke, N.; Lundqvist, E. A.; Theodorsson, E.; Ernerudh, J.; Kjölhede, P.; Einstein, G.
10.1101/2023.11.14.566928 — neuroscience — Posted on 2023-11-16
2289 Immunosuppressive tumor microenvironment of osteosarcoma
Taylor, A. M.; Ng, P. K. S.; Harder, J. M.; Kumar, P.; Dzis, A. M.; Jillette, N. L.; Goodspeed, A.; Bodlak, A.; Wu, Q.; Isakoff, M. S.; George, J.; Grassman, J. D. S.; Luo, D.; Flynn, W. F.; Courtois, E. T.; Robson, P.; Hayashi, M.; Paolillo, A. T.; de Toledo, S. R. C.; Balarezo, F. S.; Lindsay, A. D.; Hoang, B.; Lau, C. C.
10.1101/2023.11.01.565008 — cancer biology — Posted on 2023-11-16
2291 Unravelling the metastasis-preventing effect of miR-200c in vitro and in vivo
Koehler, B.; Brieger, E.; Brandstaetter, T.; Hoerterer, E.; Wilk, U.; Poehmerer, J.; Joetten, A.; Paulitschke, P.; Broedersz, C. P.; Zahler, S.; Raedler, J. O.; Wagner, E.; Roidl, A.
10.1101/2023.11.14.566527 — cancer biology — Posted on 2023-11-16
2292 Immunotherapy for ovarian cancer is improved by tumor targeted delivery of a neoantigen surrogate
Scanlon, L. R.; Gabor, L.; Khouri, O. R.; Ahmad, S.; Levy, E.; Kuo, D. Y.-S.; Lin, K.; Nevadunsky, N.; Gravekamp, C.
10.1101/2023.10.11.561944 — cancer biology — Posted on 2023-11-16
2293 PI3Kδ activation, IL6 over-expression, and CD37 loss cause resistance to the targeting of CD37-positive lymphomas with the antibody-drug conjugate naratuximab emtansine
Arribas, A. J.; Gaudio, E.; Napoli, S.; Herbaux, C. J.; Tarantelli, C.; Bordone Pittau, R.; Cascione, L.; Munz, N.; Aresu, L.; Sgrignani, J.; Rinaldi, A.; Kwee, I.; Rossi, D.; Cavalli, A.; Zucca, E.; Stussi, G.; Stathis, A.; Sloss, C.; Davids, M. S.; Bertoni, F.
10.1101/2023.11.14.566994 — cancer biology — Posted on 2023-11-16
2294 Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition
Kay, K.; Lee, J.; Hong, E. S.; Beilis, J.; Dayal, S.; Wesley, E. R.; Mitchell, S.; Wang, S. Z.; Silver, D. J.; Volovetz, J.; Johnson, S.; McGraw, M.; Grabowski, M. M.; Lu, T.; Freytag, L.; Narayana, V.; Freytag, S.; Best, S. A.; Whittle, J. R.; Wang, Z.; Reizes, O.; Yu, J. S.; Hazen, S. L.; Brown, J. M.; Bayik, D.; Lathia, J.
10.1101/2023.11.14.567048 — cancer biology — Posted on 2023-11-16
2295 Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas
Udutha, S.; Taglang, C.; Batsios, G.; Gillespie, A. M.; Tran, M.; Ronen, S. M.; ten Hoeve, J.; Graeber, T. G.; Viswanath, P.
10.1101/2023.11.14.566937 — cancer biology — Posted on 2023-11-16
2296 ADGRE5 ACTS AS A MELANOMA TUMOR SUPPRESSOR IN NATURALLY HYBRIDIZING XIPHOPHORUS.
Garcia-Olazabal, M.; Adolfi, M. C.; Wilde, B.; Hufnagel, A.; Paudel, R.; Lu, Y.; Meierjohann, S.; Rosenthal, G. G.; Schartl, M.
10.1101/2023.11.14.567049 — cancer biology — Posted on 2023-11-16
2297 Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping
Fernandez-Mateos, J.; Milite, S.; Oliveira, E.; Vlachogiannis, G.; Chen, B.; Yara, E.; Cresswell, G. D.; James, C.; Patruno, L.; Ascolani, G.; Acar, A.; Heide, T.; Spiteri, I.; Graudenzi, A.; Caravagna, G.; Graham, T.; Magnani, L.; Valeri, N.; Sottoriva, A.
10.1101/2023.11.15.567140 — cancer biology — Posted on 2023-11-16
2300 Spatial and Temporal Inhomogeneity of Magnetic Background in Cell Culture Experiments: The Role of Type and Position of CO2-Incubator in a Laboratory
Sencha, L. M.; Karpova, M. A.; Dolinin, A. A.; Sarafanov, F. G.; Ilin, N. V.; Mareev, E. A.; Vodeneev, V. A.; Grinberg, M. A.; Balalaeva, I. V.
10.1101/2023.11.14.566912 — biophysics — Posted on 2023-11-16
2310 DIISCO: A Bayesian framework for inferring dynamic intercellular interactions from time-series single-cell data
Park, C.; Mani, S.; Beltran-Velez, N.; Maurer, K.; Gohil, S.; Li, S.; Huang, T.; Knowles, D. A.; Wu, C. J.; Azizi, E.
10.1101/2023.11.14.566956 — bioinformatics — Posted on 2023-11-16
2312 High-sensitivity whole-genome recovery of single viral species in environmental samples
Chen, L.; Chen, A.; Zhang, X. D.; Saenz, M. T.; Han, H.-S.; Xiao, Y.; Xiao, G.; Pipas, J. M.; Weitz, D.
10.1101/2023.11.13.566948 — bioengineering — Posted on 2023-11-16
2314 Tissue-specific sex difference in the metabolism of fatty acid esters of hydroxy fatty acids
Riecan, M.; Domanska, V.; Lupu, C.; Patel, M.; Vondrackova, M.; Rossmeisl, M.; Saghatelian, A.; Lupu, F.; Kuda, O.
10.1101/2023.11.15.567158 — biochemistry — Posted on 2023-11-16
2317 Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-gamma on parasite restriction
Pardy, R. D.; Walzer, K. A.; Wallbank, B. A.; Byerly, J. H.; O'Dea, K. M.; Cohn, I. S.; Haskins, B. E.; Roncaioli, J. L.; Smith, E. J.; Buenconsejo, G. Y.; Striepen, B.; Hunter, C. A.
10.1101/2023.11.14.567008 — immunology — Posted on 2023-11-16
2318 Can non-invasive brain stimulation modulate peak alpha frequency in the human brain? A systematic review and meta-analysis
Millard, S. K.; Speis, D. B.; Skippen, P.; Chiang, A. K. I.; Chang, W.-J.; Lin, A. J.; Furman, A.; Mazaheri, A.; Seminowicz, D. A.; Schabrun, S.
10.1101/2023.11.13.566909 — neuroscience — Posted on 2023-11-16
2319 Transcriptional regulation of neonatal neural stem cells is a determinant of social behavior
Hiramoto, T.; Boku, S.; Kang, G.; Abe, S.; Barbachan e Silva, M.; Tanigaki, K.; Nagashima, M.; Ye, K.; Yamauchi, T.; Michurina, T. V.; O Broin, P.; Enikolopov, G.; Hiroi, N.
10.1101/2021.11.12.468452 — neuroscience — Posted on 2023-11-16
2320 Peripheral nerve injury results in a biased loss of sensory neuron sub-populations
Cooper, A. H.; Barry, A. M.; Chrysostomidou, P.; Lolignier, R.; Titterton, H. F.; Bennett, D. L.; Weir, G. A.
10.1101/2023.11.14.566863 — neuroscience — Posted on 2023-11-16
2327 kmerDB: A Database Encompassing the Set of Genomic and Proteomic Sequence Information for Each Species
Mouratidis, I.; Baltoumas, F. A.; Chantzi, N.; Chan, C.; Montgomery, A.; Konnaris, M. A.; Georgakopoulos, G. C.; Das, A.; Chartoumpekis, D.; Kovac, J.; Pavlopoulos, G.; Georgakopoulos-Soares, I.
10.1101/2023.11.13.566926 — genomics — Posted on 2023-11-16
2333 Can a flower color ancestral polymorphism transcend speciation?
Sanchez-Cabrera, M.; Narbona, E.; Arista, M.; Ortiz, P. L.; Jimenez-Lopez, F. J.; Fuller, A.; Carter, B.; Whittall, J.
10.1101/2023.11.14.566988 — evolutionary biology — Posted on 2023-11-16
2336 Photosymbiosis reduces the environmental stress response under a heat challenge in a facultatively symbiotic coral
Wuitchik, D. M.; Aichelman, H. E.; Atherton, K. F.; Brown, C. M.; Chen, X.; DiRoberts, L.; Pelose, G. E.; Tramonte, C. A.; Davies, S. W.
10.1101/2023.11.13.566890 — ecology — Posted on 2023-11-16
2337 Small dams drive Anopheles abundance during the dry season in a high malaria burden area of Malawi
Zembere, K.; Jones, C. M.; Mthawanji, R.; Nkolokosa, C.; Kamwezi, R.; Kalonde, P. K.; Stanton, M. C.
10.1101/2023.11.14.567025 — ecology — Posted on 2023-11-16
2339 A Photoactivatable Norepinephrine for Probing Adrenergic Neural Circuits
Cahill, M. K.; Perez, Y. R.; Larpthaveesarp, A.; Etchenique, R.; Poskanzer, K. E.
10.1101/2023.11.13.566764 — neuroscience — Posted on 2023-11-16
2341 Cholinergic mu-opioid receptors participate in nicotine, but not ethanol, drinking behaviors
Beane, C. R.; Lewis, D. G.; Bruns, N. K.; Pikus, K. L.; Durfee, M. H.; Zegarelli, R. A.; Perry, T. W.; Radke, A. K.
10.1101/2023.11.13.566881 — neuroscience — Posted on 2023-11-16
2342 Dorsal Motor Vagal Neurons Can Elicit Bradycardia and Reduce Anxiety-Like Behavior
Strain, M. M.; Conley, N. J.; Kauffman, L. S.; Espinoza, L.; Fedorchak, S.; Martinez, P. C.; Crook, M. E.; Jalil, M.; Hodes, G. E.; Abbott, S. B. G.; Guler, A. D.; Campbell, J. N.; Boychuk, C. R.
10.1101/2023.11.14.566855 — neuroscience — Posted on 2023-11-16
2344 Noise reduction as a unified mechanism of perceptual learning in humans, macaques, and convolutional neural networks
Cheng, Y.-A.; Sanayei, M.; Chen, X.; Jia, K.; Li, S.; Fang, F.; Watanabe, T.; Thiele, A.; Zhang, R.-Y.
10.1101/2023.11.13.566963 — neuroscience — Posted on 2023-11-16
2346 Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
Wang, G.; Guasp, R.; Salam, S.; Chuang, E.; Morera, A.; Smart, A. J.; Jimenez, D.; Shekhar, S.; Melentijevic, I.; Nguyen, K. C.; Hall, D. H.; Grant, B. D.; Driscoll, M.
10.1101/2023.11.13.565361 — neuroscience — Posted on 2023-11-16
2347 Simultaneous single-cell calcium imaging of neuronal population activity and brain-wide BOLD fMRI
Ubaghs, R. L. E. M.; Boehringer, R.; Marks, M.; Hesse, H. K.; Yanik, M. F.; Zerbi, V.; Grewe, B. F.
10.1101/2023.11.14.566368 — neuroscience — Posted on 2023-11-16
2348 A Large Field-of-View Two- and Three-Photon Microscope for High-Resolution Deep Tissue Imaging
Mok, A.; Wang, T.; Zhao, S.; Kolkman, K.; Wu, D.; Ouzounov, D.; Seo, C.; Wu, C.; Fetcho, J.; Xu, C.
10.1101/2023.11.14.566970 — neuroscience — Posted on 2023-11-16
2349 Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals
Lewis, C. T. A.; Melhedegaard, E. G.; Ognjanovic, M. M.; Olsen, M. S.; Laitila, J.; Seaborne, R. A. E.; Gronset, M. N.; Zhang, C.; Iwamoto, H.; Hessel, A. L.; Kuehn, M. N.; Merino, C.; Amigo, N.; Frobert, O.; Giroud, S.; Staples, J. F.; Goropashnaya, A. V.; Fedorov, V. B.; Barnes, B. M.; Toien, O.; Drew, K. L.; Sprenger, R. J.; Ochala, J.
10.1101/2023.11.14.566992 — physiology — Posted on 2023-11-16
2350 Evaluation of gelatin bloom strength on gelatin methacryloyl hydrogel properties
Zambuto, S. G.; Kolluru, S. S.; Ferchichi, E.; Rudewick, H.; Fodera, D. G.; Myers, K. M.; Zustiak, S. P.; Oyen, M. L.
10.1101/2023.11.13.566924 — bioengineering — Posted on 2023-11-16
2351 Latitudinal gradients in predation persist in urban environments
Hargreaves, A. L.; Ensing, J.; Rahn, O. J.; Oliveira, F. M. P.; Burkiewicz, J.; Lafond, J.; Haeussler, S.; Byerley-Best, M. B.; Lazda, K.; Slinn, H.; Martin, E.; Carlson, M. L.; Sformo, T. L.; Dawson-Glass, E.; Chiuffo, M. C.; Vargas-Rodriguez, Y. L.; Garcia-Jimenez, C. I.; Gomes, I. J.; Klemet-N'Guessan, S.; Paolucci, L. N.; Joly, S.; Mehltreter, K.; Munoz, J.; Buono, C.; Brodie, J. F.; Rodriguez-Campbell, A.; Veen, T.; Freeman, B.; Lee-Yaw, J. A.; Munoz, J. C.; Paquette, A.; Butler, J.; Suarez, E.
10.1101/2023.11.14.566324 — ecology — Posted on 2023-11-16
2352 ATP burst is the dominant driver of antibiotic lethality in Mycobacteria
Lodhiya, T.; Palande, A.; Veeram, A.; Larrouy-Maumus, G.; Beste, D. J.; Mukherjee, R.
10.1101/2023.09.11.557291 — microbiology — Posted on 2023-11-16
2362 Ovipin: a chicken eggs antibiotic agent
dos Santos, S. R.; Miranda, A.; Silva Junior, P. I.
10.1101/2021.09.28.462162 — microbiology — Posted on 2023-11-16
2367 An antimicrobial peptide expression platform for targeting pathogenic bacterial species
Rutter, J. W.; Dekker, L.; Clare, C.; McDonald, J. A.; Nair, S. P.; Fedorec, A. J.; Barnes, C. P.
10.1101/2023.10.09.561505 — synthetic biology — Posted on 2023-11-16
2368 Regenerative Signatures in Bronchioalveolar Lavage of Acute Respiratory Distress Syndrome
Zhao, R.; Hadisurya, M.; Ndetan, H.; Xi, N. M.; Adduri, S.; Konduru, N. V.; Samten, B. M.; Tao, A. W.; Singh, K. P.; Ji, H.-L.
10.1101/2023.11.13.566908 — pathology — Posted on 2023-11-16
2369 A chromosome-level genome for the nudibranch gastropod Berghia stephanieae helps parse clade-specific gene expression in novel and conserved phenotypes
Goodheart, J. A.; Rio, R. A.; Taraporevala, N. F.; Fiorenza, R. A.; Barnes, S. R.; Morrill, K.; Jacob, M. A. C.; Whitesel, C.; Masterson, P.; Batzel, G. O.; Johnston, H. T.; Ramirez, M. D.; Katz, P. S.; Lyons, D.
10.1101/2023.08.04.552006 — genomics — Posted on 2023-11-16
2371 O-antigen biosynthesis mediates evolutionary trade-offs within a simple community
Spencer-Drakes, T. C. J.; Sarabia, A.; Heussler, G.; Pierce, E. C.; Morin, M.; Villareal, S.; Dutton, R. J.
10.1101/2023.11.15.566321 — microbiology — Posted on 2023-11-16
2374 Waveform-based classification of dentate spikes
Santiago, R. M.; Lopes-dos-Santos, V.; Jones, E. A. A.; Huang, Y.; Dupret, D.; Tort, A. B.
10.1101/2023.10.24.563826 — neuroscience — Posted on 2023-11-16
2375 HY5 regulates GLK transcription factors to orchestrate photomorphogenesis in Arabidopsis thaliana
Zhang, T.; Zhang, R.; Zeng, X.; Lee, S.; Ye, L.; Tian, S.; Zhang, Y.; Busch, W.; Zhou, W. B.; Zhu, X.-G.; Wang, P.
10.1101/2022.09.30.510343 — plant biology — Posted on 2023-11-16
2380 Global and local redistribution of somatic mutations enable the prediction of functional XPD mutations in bladder cancer
Barbour, J. A.; Ou, T.; Fang, H.; Yue, N. C.; Zhu, X.; Wong-Brown, M.; Yang, H.; Wong, Y. T.; Bowden, N. A.; Wu, S.; Wong, J. W. H.
10.1101/2022.01.21.477237 — molecular biology — Posted on 2023-11-16
2382 nucMACC: A MNase-seq pipeline to identify structurally altered nucleosomes in the genome
Wernig-Zorc, S.; Kugler, F.; Schmutterer, L.; Raess, P.; Hausmann, C.; Holzinger, S.; Laengst, G.; Schwartz, U.
10.1101/2022.12.29.521985 — bioinformatics — Posted on 2023-11-16
2383 Multi-genome comparisons reveal gain-and-loss evolution of the anti-Mullerian hormone receptor type 2 gene, an old master sex determining gene, in Percidae
Kuhl, H.; Euclide, P.; Klopp, C.; Cabau, C.; Zahm, M.; Lopez-Roques, C.; Iampietro, C.; Kuchly, C.; Donnadieu, C.; Feron, R.; Parrinello, H.; Poncet, C.; Jaffrelo, L.; Confolent, C.; Wen, M.; Herpin, A.; Jouanno, E.; Bestin, A.; Haffray, P.; Morvezen, R.; Rocha de Almeida, T.; Lecocq, T.; Schaerlinger, B.; Chardard, D.; Zarski, D.; Larson, W.; Postlethwait, J.; Timirkhanov, S.; Kloas, W.; Wuertz, S.; Stock, M.; Guiguen, Y.
10.1101/2023.11.13.566804 — genomics — Posted on 2023-11-16
2385 Generation and characterization of Sema6aΔcyt conditional knockout mice
Verhagen, M. G.; van Battum, E. Y.; van den Munkhof, M. H.; Lemstra, S.; Rehberg, K.; Koutourlou, A.; Jansen, K.; van der Meer, C.; van Kronenburg, N. C. H.; Adolfs, Y.; Pasterkamp, R. J.
10.1101/2023.11.06.565851 — developmental biology — Posted on 2023-11-16
2387 Alternative splicing controls teneurin-3 compact dimer formation for neuronalrecognition
Gogou, C.; Beugelink, J. W.; P. Frias, C.; Kresik, L.; Jaroszynska, N.; Drescher, U.; Janssen, B. J. C.; Hindges, R.; Meijer, D. H.
10.1101/2023.10.27.564434 — biochemistry — Posted on 2023-11-16
2388 Evolution of genotypic and phenotypic diversity in multispecies biofilms
Amador, C. I.; Moskovitz, S. Z.; Maccario, L.; Herschend, J.; Kramer, I. S.; Jeckel, H.; Cooper, V. S.; Drescher, K.; Neu, T. R.; Burmolle, M.; Roder, H. L.
10.1101/2023.10.08.561388 — microbiology — Posted on 2023-11-16
2391 Characterization of N-glycosylation and its Functional Role in SIDT1-Mediated RNA Uptake
Yang, T.; Xiao, H.; Chen, X.; Zheng, L.; Guo, H.; Wang, J.; Jiang, X.; Zhang, C.-Y.; Yang, F.; Ji, X.
10.1101/2023.08.01.551569 — biochemistry — Posted on 2023-11-16
2392 Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds
Julio, A. R.; Shikwana, F.; Truong, C.; Burton, N. R.; Dominguez, E.; Turmon, A.; Cao, J.; Backus, K.
10.1101/2023.10.30.564067 — biochemistry — Posted on 2023-11-16
2396 The development of the adult nervous system in the annelid Owenia fusiformis
Carrillo-Baltodano, A. M.; Donnellan, R. D.; Williams, E. A.; Jekely, G.; Martin-Duran, J. M.
10.1101/2023.11.14.567050 — developmental biology — Posted on 2023-11-16
2397 Self-organised pattern formation in the developing neural tube by a temporal relay of BMP signalling
Lehr, S.; Brueckner, D. B.; Greunz-Schindler, M.; Minchington, T. G.; Merrin, J.; Hannezo, E.; Kicheva, A.
10.1101/2023.11.15.567070 — developmental biology — Posted on 2023-11-16
2398 Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis
Kotb, N. M.; Ulukaya, G.; Chavan, A.; Nguyen, S. C.; Proskauer, L.; Joyce, E. F.; Hasson, D.; Jagannathan, M.; Rangan, P.
10.1101/2023.11.15.567233 — developmental biology — Posted on 2023-11-16
2399 Heparan sulfate dependent phase separation of CCL5 and its chemotactic activity
Yu, X.; Duan, G.; Pei, P.; Chen, L.; Gu, R.; Hu, W.; Zhang, H.; Wang, Y.-D.; Gong, L.; Liu, L.; Chu, T.-T.; Li, J.-P.; Luo, S.-Z.
10.1101/2023.11.15.567182 — cell biology — Posted on 2023-11-16
2402 Mitochondria possess a large, non-selective ionic current that is enhanced during cardiac injury.
Balderas, E.; Lee, S. H. J.; Shankar, T. S.; Yin, X.; Balynas, A. M.; Kyriakopoulos, C. P.; Selzman, C. H.; Drakos, S. G.; Chaudhuri, D.
10.1101/2023.11.15.567241 — cell biology — Posted on 2023-11-16
2405 Single-cell morphological tracking of liver cell states to identify small-molecule modulators of liver differentiation
Graham, R. E.; Zheng, R.; Wagner, J.; Unciti-Broceta, A.; Hay, D. C.; Forbes, S. J.; Gadd, V. L.; Carragher, N. O.
10.1101/2023.11.15.567184 — cell biology — Posted on 2023-11-16
2406 RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality
Ibrahim, H.; Balboa, D.; Saarimäki-Vire, J.; Montaser, H.; Dyachok, O.; Lund, P.-E.; Omar-Hmeadi, M.; Kvist, J.; Dwivedi, O. P.; Lithovius, V.; Barsby, T.; Chandra, V.; Eurola, S.; Ustinov, J.; Tuomi, T.; Miettinen, P. J.; Barg, S.; Tengholm, A.; Otonkoski, T.
10.1101/2023.11.15.567202 — cell biology — Posted on 2023-11-16
2408 Transcriptional profile of the rat cardiovascular system at single cell resolution
Arduini, A.; Fleming, S. J.; Xiao, L.; Hall, A. W.; Akkad, A.-D.; Chaffin, M. D.; Bendinelli, K. J.; Tucker, N. R.; Papangeli, I.; Mantineo, H.; Babadi, M.; Stegmann, C. M.; Garcia-Cardena, G.; Lindsay, M. E.; Klattenhoff, C.; Ellinor, P. T.
10.1101/2023.11.14.567085 — cell biology — Posted on 2023-11-16
2412 Axon development is regulated at genetic and proteomic interfaces between the integrin adhesome and the RPM-1 ubiquitin ligase signaling hub
Amezquita, J.; Desbois, M.; Opperman, K.; Pak, J. S.; Christensen, E. L.; Nguyen, N. T.; Diaz-Garcia, K.; Borgen, M. A.; Grill, B.
10.1101/2023.11.15.566604 — neuroscience — Posted on 2023-11-15
2413 Pushing the boundaries of on-scalp magnetoencephalography towards early human life
Corvilain, P.; Wens, V.; Bourguignon, M.; Capparini, C.; Fourdin, L.; Ferez, M.; Feys, O.; De Tiege, X.; Bertels, J.
10.1101/2023.10.28.564455 — neuroscience — Posted on 2023-11-16
2414 "When I talk about it, my eyes light up!" Impacts of a national laboratory internship on community college student success
Cote, L. E.; Van Doren, S.; Zamora, A. N.; Jaramillo Salcido, J.; Law, E. W.; Otero Munoz, G.; Manocha, A.; Flood, C. L.; Baranger, A. M.
10.1101/2023.05.08.539924 — scientific communication and education — Posted on 2023-11-16
2418 Maturational Differences in Affective Behaviors Involves Changes in Frontal Cortical-Hippocampal Functional Connectivity and Metabolomic Profiles
Febo, M.; Mahar, R.; Rodriguez, N. A.; Buraima, J.; Pompilus, M.; Pinto, A. M.; Grudny, M. M.; Bruijnzeel, A.; Merritt, M.
10.1101/2023.11.13.566691 — neuroscience — Posted on 2023-11-15
2421 Connectivity Regression
Desai, N.; Baladandayuthapani, V.; Shinohara, R. T.; Morris, J.
10.1101/2023.11.14.567081 — neuroscience — Posted on 2023-11-15
2422 Creation of de novo cryptic splicing for ALS/FTD precision medicine
Wilkins, O. G.; Chien, M. Z. Y. J.; Wlaschin, J. J.; Pisliakova, M.; Thompson, D.; Digby, H.; Simkin, R. L.; Diaz, J. A.; Mehta, P. R.; Keuss, M. J.; Zanovello, M.; Brown, A.-L.; Harley, P.; Darbey, A.; Karda, R.; Fisher, E. M. C.; Cunningham, T. J.; Le Pichon, C. E.; Ule, J.; Fratta, P.
10.1101/2023.11.15.565967 — molecular biology — Posted on 2023-11-15
2423 SUMO chains depolymerization induces slender to stumpy differentiation in T. brucei bloodstream parasites
Iribarren, P. A.; Di Marzio, L. A.; Berazategui, M. A.; Saura, A.; Coria, L. M.; Cassataro, J.; Rojas, F.; Navarro, M.; Alvarez, V. E.
10.1101/2023.11.15.567218 — molecular biology — Posted on 2023-11-15
2424 Unravelling the regulatory function of a short 3'UTR sequence in zebrafish and in human cells
Eufrasio, A.; Azevedo, J.; Machado, J.; Ferreira, A.; Moutinho, A.; Henriques, F.; Jesus, A.; Tavares, J.; Pereira-Castro, I.; Teixeira, J.; Pinto, P. A.; Bessa, J.; Moreira, A.
10.1101/2023.11.15.567165 — molecular biology — Posted on 2023-11-15
2426 Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite antagonistic effects in heart contraction
Auguin, D.; Robert-Paganin, J.; Rety, S.; Kikuti, C.; David, A.; Theumer, G.; Schmidt, A. W.; Knoelker, H.-J.; Houdusse, A.
10.1101/2023.11.15.567213 — molecular biology — Posted on 2023-11-15
2430 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbiome
Lindon, S.; Shah, S.; Gifford, D. R.; Gomis Font, M. A.; Kaur, D.; Oliver, A.; MacLean, R. C.; Wheatley, R. M.
10.1101/2023.11.14.567137 — microbiology — Posted on 2023-11-15
2431 Boronic acid derivative inhibits LexA mediated SOS response in Mycobacteria
Chatterjee, C.; Mohan, G. R.; Chinnasamy, H. V.; Biswas, B.; Sundaram, V.; Srivatsava, A.; Matheshwaran, S.
10.1101/2023.11.15.567215 — microbiology — Posted on 2023-11-15
2432 O-antigen biosynthesis mediates evolutionary trade-offs within a simple community
Spencer-Drakes, T. C. J.; Sarabia, A.; Heussler, G.; Pierce, E. C.; Morin, M.; Dutton, R. J.; Villareal, S.
10.1101/2023.11.15.566321 — microbiology — Posted on 2023-11-15
2433 Oxidation of hemoglobin in the lung parenchyma facilitates the differentiation of pneumococci into encapsulated bacteria
Alibayov, B.; Scasny, A.; Jop Vidal, A. G.; Murin, L.; Wong, S. M.; Edwards, K.; Eichembaun, Z.; Punshon, T.; Jackson, B.; Hopp, M.-T.; McDaniel, L. S.; Akerley, B. J.; Imhof, D.; Vidal, J. E.
10.1101/2023.11.14.567109 — microbiology — Posted on 2023-11-15
2435 Structural and functional basis of VLDLR receptor usage by Eastern equine encephalitis virus
Adams, L. J.; Raju, S.; Ma, H.; Gilliland, T.; Reed, D. S.; Klimstra, W. B.; Fremont, D. H.; Diamond, M. S.
10.1101/2023.11.15.567188 — microbiology — Posted on 2023-11-15
2441 Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket
Huang, C.-Y.; Metz, A.; Lange, R.; Artico, N.; Potot, C.; Hazemann, J.; Mueller, M.; Dos Santos, M.; Chambovey, A.; Ritz, D.; Eris, D.; Meyer, S.; Bourquin, G.; Sharpe, M. E.; Mac Sweeney, A.
10.1101/2023.11.15.567102 — biophysics — Posted on 2023-11-15
2442 Engineering self-deliverable ribonucleoproteins for genome editing in the brain
Chen, K.; Stahl, E. C.; Kang, M. H.; Xu, B.; Allen, R.; Trinidad, M.; Doudna, J. A.
10.1101/2023.11.15.567251 — bioengineering — Posted on 2023-11-15
2443 A Method for Sampling the Living Wood Microbiome
Arnold, W.; Gewirtzman, J.; Raymond, P. A.; Bradford, M.; Butler, C.; Peccia, J.
10.1101/2023.11.14.567064 — ecology — Posted on 2023-11-15
2446 Directed Evolution of Genetically Encoded LYTACs for Cell-Mediated Delivery
Yang, J. L.; Yamada-Hunter, S. A.; Labanieh, L.; Sotillo, E.; Cheah, J. S.; Roberts, D. S.; Mackall, C.; Ting, A. Y.; Bertozzi, C.
10.1101/2023.11.14.567117 — synthetic biology — Posted on 2023-11-15
2447 CCR5/CXCR3 antagonist TAK-779 prevents diffuse alveolar damage of the lung in murine model of the SARS-CoV-2-related acute respiratory distress syndrome
Chernov, A.; Rodionov, M.; Kazakov, V.; Ivanova, K.; Mesheryakov, F.; Kudriaeva, A.; Gabibov, A.; Telegin, G.; Belogurov, A.
10.1101/2023.11.14.567145 — pathology — Posted on 2023-11-15
2448 Gait speed is a biomarker of cancer-associated cachexia decline and recovery
Roy, I.; Binder-Markey, B.; Sychowski, D.; Willbanks, A.; Phipps, T.; McAllister, D.; Bhakta, A.; Marquez, E.; D'Andrea, D.; Franz, C.; Pichika, R.; Dwinell, M.; Jayabalan, P.; Lieber, R. L.
10.1101/2023.11.13.566852 — cancer biology — Posted on 2023-11-15
2450 The mechanism of mRNA activation
Gentry, R. C.; Ide, N. A.; Comunale, V. M.; Hartwick, E. W.; Kinz-Thompson, C. D.; Gonzalez, R. L.
10.1101/2023.11.15.567265 — biophysics — Posted on 2023-11-15
2451 UNSEG: unsupervised segmentation of cells and their nuclei in complex tissue samples
Kochetov, B.; Bell, P.; Garcia, P. S.; Shalaby, A. S.; Raphael, R.; Raymond, B.; Leibowitz, B. J.; Schoedel, K.; Brand, R. M.; Brand, R. E.; Yu, J.; Zhang, L.; Diergaarde, B.; Schoen, R. E.; Singhi, A.; Uttam, S.
10.1101/2023.11.13.566842 — bioinformatics — Posted on 2023-11-15
2452 COVID-19-related research data availability and quality according to the FAIR principles: A meta-research study
Sofi-Mahmudi, A.; Raittio, E.; Khazaei, Y.; Ashraf, J.; Schwendicke, F.; Uribe, S. E.; Moher, D.
10.1101/2023.11.14.566998 — bioinformatics — Posted on 2023-11-15
2454 Host JAK/Stat activity is a target of endoparasitoid wasp virulence strategies
Brantley, S. E.; Stouthamer, C. M.; KR, P.; Fischer, M. L.; Hill, J.; Schlenke, T. A.; Mortimer, N. T.
10.1101/423335 — cell biology — Posted on 2023-11-15
2456 Virological characteristics of the SARS-CoV-2 Omicron HK.3 variant harboring the "FLip" substitution
Kosugi, Y.; Plianchaisuk, A.; Putri, O.; Uriu, K.; Kaku, Y.; Hinay, A. A.; Chen, L.; Kuramochi, J.; Sadamasu, K.; Yoshimura, K.; Asakura, H.; Nagashima, M.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2023.11.14.566985 — microbiology — Posted on 2023-11-15
2457 SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling
Otter, C. J.; Bracci, N.; Parenti, N. A.; Ye, C.; Li Hui, T.; Asthana, A.; Pfannenstiel, J. J.; Jackson, N.; Fehr, A. R.; Silverman, R. H.; Cohen, N. A.; Martinez-Sobrido, L.; Weiss, S. R.
10.1101/2023.11.15.566945 — microbiology — Posted on 2023-11-15
2461 A monochromatically excitable green-red dual-fluorophore fusion incorporating a new large Stokes shift fluorescent protein
Ejike, J. O.; Sadoine, M.; Shen, Y.; Ishikawa, Y.; Sunal, E.; Hänsch, S.; Hamacher, A. B.; Frommer, W. B.; Wudick, M. M.; Campbell, R. E.; Kleist, T. J.
10.1101/2023.07.16.549156 — bioengineering — Posted on 2023-11-15
2463 Continent-wide genomic analysis of the African buffalo (Syncerus caffer).
Talenti, A.; Wilkinson, T.; Cook, E. A.; Hemmink, J. D.; Paxton, E.; Mutinda, M.; Ngulu, S. D.; Jayaraman, S.; Bishop, R. P.; Obara, I.; Hourlier, T.; Garcia Giron, C.; Martin, F. J.; Labuschagne, M.; Atimnedi, P.; Nanteza, A.; Keyyu, J. D.; Mramba, F.; Caron, A.; Cornelis, D.; Chardonnet, P.; Fyumagwa, R.; Lembo, T.; Auty, H. K.; Michaux, J.; Smitz, N.; Toye, P.; Robert, C.; Prendergast, J. G. D.; Morrison, L. J.
10.1101/2023.11.12.566748 — genomics — Posted on 2023-11-15
2464 Genetic Diversity and Structural Complexity of the Killer-Cell Immunoglobulin-Like Receptor Gene Complex: A Comprehensive Analysis using Human Pangenome Assemblies
Hung, T.-K.; Liu, W.-C.; Lai, S.-K.; Chuang, H.-W.; Lee, Y.-C.; Lin, H.-Y.; Hsu, C.-L.; Chen, C.-Y.; Yang, Y.-C.; Hsu, J. S.; Chen, P.-L.
10.1101/2023.11.12.566753 — genomics — Posted on 2023-11-15
2468 Darwin's "neuters" and the evolution of the sex continuum in a superorganism
Oettler, J.; Wallner, T.; Dofka, B.; Heinze, J.; Eichner, N.; Meister, G.; Errbii, M.; Rehli, M.; Gebhard, C.; Schultner, E.
10.1101/2023.11.13.566820 — evolutionary biology — Posted on 2023-11-15
2469 Copepodamides in marine and freshwater copepods -similar but different
Arnoldt, S.; Pourdanandeh, M. H.; Spikkeland, I.; Andersson, M. X.; Selander, E.
10.1101/2023.11.13.566526 — ecology — Posted on 2023-11-15
2470 Bacterial community characterization by deep learning aided image analysis in soil chips
Zou, H.; Sopasakis, A.; Maillard, F.; Karlsson, E.; Duljas, J.; Silwer, S.; Ohlsson, P.; Hammer, E. C.
10.1101/2023.11.13.566656 — ecology — Posted on 2023-11-15
2471 Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats
Amen, A.; Yoo, R.; Fabra-Garcia, A.; Bolscher, J.; Stone, W. J. R.; Bally, I.; Dergan-Dylon, S.; Kucharska, I.; de Jong, R. M.; de Bruijni, M.; Bousema, T.; King, C. R.; MacGill, R. S.; Sauerwein, R. W.; Julien, J.-P.; Poignard, P.; Jore, M. M.
10.1101/2023.11.03.565335 — immunology — Posted on 2023-11-15
2472 Convergent evolution of monocyte differentiation in adult skin permits repair of the Langerhans cell network
Appios, A.; Davies, J.; Sirvent, S.; Henderson, S.; Trzebanski, S.; Schroth, J.; Law, M. L.; Boal Carvalho, I.; Yuan-Hao Kan, H.; Major, C.; Vallejo, A.; Hall, N. J.; Ardern-Jones, M.; Henson, S. M.; Emmerson, E.; Jung, S.; Polak, M. E.; Bennett, C. L.
10.1101/2023.11.13.566862 — immunology — Posted on 2023-11-15
2474 Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome 22 and Prader Willi Syndrome
BHALLA, K.; Rosier, K.; Monnens, Y.; Meulemans, S.; Vervoort, E.; Thorrez, L.; Agostinis, P.; T. Meier, D.; Rochtus, A.; Resnick, J.; Creemers, J.
10.1101/2023.11.12.566752 — neuroscience — Posted on 2023-11-15
2475 Galectin-3 depletion tames pro-tumoural microglia and restrains cancer cells growth
Cruz-Hernandez, L.; Sanchez-Montero, M. T.; Rivera-Ramos, A.; Garcia-Revilla, J.; Mulero, M.; Taleveron, R.; Venero, J. L.; Sarmiento Soto, M.
10.1101/2023.11.13.563707 — neuroscience — Posted on 2023-11-15
2481 AutoPeptideML: Automated Machine Learning for Building Trustworthy Peptide Bioactivity Predictors
Fernandez-Diaz, R.; Cossio-Perez, R.; Agoni, C.; Hoang, L. T.; Lopez, V.; Shields, D. C.
10.1101/2023.11.13.566825 — bioinformatics — Posted on 2023-11-15
2482 TranSiGen: Deep representation learning of chemical-induced transcriptional profile
Tong, X.; Qu, N.; Kong, X.; Ni, S.; Wang, K.; Zhang, L.; Wen, Y.; Zhang, S.; Li, X.; Zheng, M.
10.1101/2023.11.12.566777 — bioinformatics — Posted on 2023-11-15
2486 Global patterns in gene content of soil microbiomes emerge from microbial interactions
Crocker, K.; Lee, K. K.; Chakraverti-Wuerthwein, M.; Li, Z.; Tikhonov, M.; Mani, M.; Gowda, K.; Kuehn, S.
10.1101/2023.05.31.542950 — ecology — Posted on 2023-11-15
2488 Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heart.
Stuedemann, T.; Schwarzova, B.; Schneidewind, T.; Geertz, B.; von Bibra, C.; Nehring, M.; Roessinger, J.; Wiegert, J. S.; Eschenhagen, T.; Weinberger, F.
10.1101/2023.11.12.566756 — pharmacology and toxicology — Posted on 2023-11-15
2492 S-Phase induced RNAs control ORC1 engagement to H2A.Z and firing of early DNA replication origins.
Ummarino, S.; Poluben, L.; Ebralidze, A. K.; Autiero, I.; Zhang, Y.; Paniza, T.; Deshpande, M.; Lee, J. D.; Bassal, M.; Trinh, B. Q.; Balk, S.; Flaumenhaft, R.; Gerhardt, J.; Mirkin, S. M.; Tenen, D. G.; Di Ruscio, A.
10.1101/2021.10.19.465050 — molecular biology — Posted on 2023-11-15
2494 Genome-wide CRISPR screen identifies KEAP1 as a genetic dependency of ARID1A in an ovarian clear cell carcinoma model
Fournier, L.-A.; Kalantari, F.; Wells, J. P.; Lee, J. S.; Trigo-Gonzalez, G.; Moksa, M. M.; Smith, T.; White, J.; Shanks, A.; Wang, L.; Su, E.; Wang, Y.; Huntsman, D. G.; Hirst, M.; Stirling, P. C.
10.1101/2023.11.14.566591 — cancer biology — Posted on 2023-11-15
2496 Rapid Adeno-Associated Virus Genome Quantification with Amplification-Free CRISPR-Cas12a
Hetzler, Z.; Marinakos, S. M.; Lott, N.; Mohammad, N.; Lass-Napiorkowska, A.; Kolbe, J.; Turrentine, L.; Fields, D.; Overton, L.; Marie, H.; Hucknall, A.; Rammo, O.; George, H.; Wei, Q.
10.1101/2023.11.14.567134 — bioengineering — Posted on 2023-11-15
2497 Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP
Chen, K.; Han, H.; Zhao, S.; Xu, B.; Yin, B.; Trinidad, M.; Burgstone, B. W.; Murthy, N.; Doudna, J. A.
10.1101/2023.11.15.566339 — bioengineering — Posted on 2023-11-15
2498 Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm
Wu, Z.; Zheng, G.; Sun, Y.; Dong, X.; Wang, Y.; Li, H.; Niu, Y.; Huang, Z.; Hu, J.; Liu, Z.
10.1101/2023.11.12.566742 — genomics — Posted on 2023-11-15
2499 Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.
Ullah, A.; Rittchen, S.; Li, J.; Curren, B. F.; Rahman, M. M.; Sikder, M. A. A.; Rashid, R. B.; Collinson, N.; Lor, M.; Smythe, M. L.; Phipps, S.
10.1101/2023.11.12.566772 — immunology — Posted on 2023-11-15
2505 Optical ice thickness measurement in the VitroJet for time-efficient single particle structure determination
Henderikx, R. J. M.; Shahzad, S.; Schotman, M. J. G.; Mann, D.; Heidler, T. V.; Ashtiani, D.; Jeurissen, R. J. M.; Peters, P. J.; Sachse, C.; Beulen, B. W. A. M. M.
10.1101/2023.10.09.561488 — molecular biology — Posted on 2023-11-15
2507 Phosphorylation alters FMRP granules and determines their transport or protein synthesis abilities
Kharod, S. C.; Hwang, D.-w.; Choi, H.; Yoon, K. J.; Castillo, P. E.; Singer, R. H.; Yoon, Y. J.
10.1101/2023.03.15.532613 — neuroscience — Posted on 2023-11-15
2508 Dual spatio-temporal regulation of axon growth and microtubule dynamics by RhoA signaling pathways
Wojnacki, J.; Quassollo, G.; Bordenave, M. D.; Unsain, N.; Martinez, G. F.; Szalai, A. M.; Pertz, O.; Gundersen, G. G.; Bartolini, F.; Stefani, F. D.; Caceres, A.; Bisbal, M.
10.1101/2023.04.17.537156 — neuroscience — Posted on 2023-11-15
2510 Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
Rasmussen, D. M.; Semonis, M. M.; Greene, J. T.; Muretta, J. M.; Thompson, A. R.; Ramos, S. T.; Thomas, D. D.; Pomerantz, W. C. K.; Freedman, T. S.; Levinson, N. M.
10.1101/2023.04.18.536450 — biophysics — Posted on 2023-11-15
2516 Leveraging whole genome sequencing to promote genetic diversity and population health in zoo-housed western lowland gorillas
Gorzynski, J.; Danforth, M. D.; Strong, V.; Kutinsky, I.; Murphy, H.; Lowenstine, L.; Priest, J. R.; Ashley, E. A.
10.1101/2023.11.13.565567 — zoology — Posted on 2023-11-15
2517 Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy
Vaniya, A.; Karlstaedt, A.; Ates Gulkok, D.; Thottakara, T.; Liu, Y.; Fan, S.; Eades, H.; Fukunaga, R.; Vernon, H. J.; Fiehn, O.; Abraham, M. R.
10.1101/2023.11.10.564562 — systems biology — Posted on 2023-11-15
2518 ProkBERT Family: Genomic Language Models for Microbiome Applications
Ligeti, B.; Szepesi-Nagy, I.; Bodnar, B.; Ligeti-Nagy, N.; Juhasz, J.
10.1101/2023.11.09.566411 — bioinformatics — Posted on 2023-11-15
2519 Targeting Sex Determination to Suppress Mosquito Populations
Li, M.; Kandul, N. P.; Sun, R.; Yang, T.; Benetta, E. D.; Brogan, D. J.; Antoshechkin, I.; Sanchez C., H. M.; Zhan, Y.; DeBeaubien, N. A.; Loh, Y. M.; Su, M. P.; Montell, C.; Marshall, J. M.; Akbari, O. S.
10.1101/2023.04.18.537404 — bioengineering — Posted on 2023-11-15
2520 Fibril Paint to detect Amyloids and determine Fibril Length
Aragones Pedrola, J.; Dekker, F. A.; Garfagnini, T.; Mayer, G.; Koopman, M. B.; Bergmeijer, M.; Forster, F.; Hoozemans, J. J.; Jensen, H.; Friedler, A.; Rudiger, S. G.
10.1101/2023.10.13.562220 — biochemistry — Posted on 2023-11-15
2523 ROS-mediated TNFR Wengen activation in response to apoptosis
Esteban-Collado, J.; Fernandez-Manas, M.; Fernandez-Moreno, M.; Maeso, I.; Corominas, M.; Serras, F.
10.1101/2023.11.13.566843 — developmental biology — Posted on 2023-11-15
2525 Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment
Hatae, R.; Kyewalabye, K.; Yamamichi, A.; Chen, T.; Phyu, S.; Chuntova, P.; Nejo, T.; Levine, L. S.; Spitzer, M. H.; Okada, H.
10.1101/2023.11.13.566775 — immunology — Posted on 2023-11-15
2528 Pyruvate Oxidation Sustains B Cell Antigen-Specific Activation to Exacerbate MASH
Barrow, F.; Wang, H.; Fredrickson, G.; Florczak, K.; Ciske, E.; Khanal, S.; Parthiban, P.; Nguyen, H.; Rios, E.; Kostallari, E.; Revelo, X.
10.1101/2023.11.13.566832 — physiology — Posted on 2023-11-15
2529 Pre-existing Subclones Determine Radioresistance in Rectal Cancer Organoids
Andel, D.; Viergever, B.; Peters, N.; Raats, D.; van Schelven, S.; Intven, M.; Zandvliet, M.; Hagendoorn, J.; Borel Rinkes, I.; Kranenburg, O.
10.1101/2023.11.02.565315 — cancer biology — Posted on 2023-11-15
2531 Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA
James, C. D.; Youssef, A.; Tadimari Prabhakar, A.; Otoa, R.; Witt, A.; Lewis, R. L.; Bristol, M. L.; Wang, X.; Zhang, K.; Li, R.; Morgan, I. M.
10.1101/2023.11.13.566899 — cancer biology — Posted on 2023-11-15
2533 Deep generative model deciphers derailed trajectories in acute myeloid leukemia
Nazaret, A.; Fan, J. L.; Lavallee, V.-P.; Cornish, A. E.; Kiseliovas, V.; Masilionis, I.; Chun, J.; Bowman, R. L.; Eisman, S. E.; Wang, J.; Shi, L.; Levine, R. L.; Mazutis, L.; Blei, D.; Pe'er, D.; Azizi, E.
10.1101/2023.11.11.566719 — bioinformatics — Posted on 2023-11-15
2536 Role of RIPK1 in Diffuse Gliomas pathology
Amoros Morales, L. C.; Gomez Bergna, S. M.; Marchesini, A.; Scalise, M. L.; Gonzalez, N.; Candolfi, M.; Romanowski, V.; Pidre, M. L.
10.1101/2023.11.11.566709 — bioinformatics — Posted on 2023-11-15
2537 Exploring the Therapeutic Potential of Cannabis Constituents in Parkinson's Disease: Insights from Molecular Docking Studies
Aziz, M.; Rehman, H.; Iqbal, A.; Nawaz, A.; Arshad, F.; Hussain, M.; Siddique, T.; Sehgal, A.; Sajid, M.
10.1101/2023.11.11.566677 — bioinformatics — Posted on 2023-11-15
2538 Synthetic Echocardiograms Generation Using Diffusion Models
Olive Pellicer, A.; Yadav, A. K. S.; Bhagtani, K.; Xiang, Z.; Pizlo, Z.; Gradus-Pizlo, I.; Delp, E. J.
10.1101/2023.11.11.566718 — bioengineering — Posted on 2023-11-15
2539 Multi-genome comparisons reveal gain-and-loss evolution of the anti-Mullerian hormone receptor type 2 gene, an old master sex determining gene, in Percidae
Kuhl, H.; Euclide, P.; Klopp, C.; Cabau, C.; Zahm, M.; Lopez-Roques, C.; Lampietro, C.; Kuchly, C.; Donnadieu, C.; Feron, R.; Parrinello, H.; Poncet, C.; Jaffrelo, L.; Confolent, C.; wen, m.; Herpin, A.; Jouanno, E.; Bestin, A.; Haffray, P.; Morvezen, R.; Rocha de Almeida, T.; Lecocq, T.; Schaerlinger, B.; Chardard, D.; Zarski, D.; Larson, W.; Postlethwait, J.; Timirkhanov, S.; Kloas, W.; Wuertz, S.; Stock, M.; Guiguen, Y.
10.1101/2023.11.13.566804 — genomics — Posted on 2023-11-15
2541 Rapid meiotic prophase chromosome movements in Arabidopsis thaliana are linked to essential reorganization at the nuclear envelope
Cromer, L.; Tiscareno-Andrade, M.; Lefranc, S.; Chambon, A.; Hurel, A.; Brogniez, M.; Guerin, J.; Le Masson, i.; Adam, G.; Charif, D.; Andrey, P.; Grelon, M.
10.1101/2023.11.13.566812 — genetics — Posted on 2023-11-15
2546 Sclerostin modulates the degree of mineralization and the stiffness profile of the fibrocartilaginous enthesis for mechanical tissue integrity
Yambe, S.; Yoshimoto, Y.; Ikeda, K.; Maki, K.; Takimoto, A.; Higuchi, S.; Yu, X.; Uchibe, K.; Miura, S.; Watanabe, H.; Sakuma, T.; Yamamoto, T.; Tanimoto, K.; Kondoh, G.; Docheva, D.; Adachi, T.; Shukunami, C.
10.1101/2023.11.13.565114 — developmental biology — Posted on 2023-11-15
2548 Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation
Tanaka, J.; Miura, A.; Shimamura, Y.; Hwang, Y.; Shimizu, D.; Kondo, Y.; Sawada, A.; SARMAH, H.; Ninish, Z.; Mishima, K.; Mori, M.
10.1101/2023.11.13.566845 — developmental biology — Posted on 2023-11-15
2549 The helminth TGF-beta mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-beta receptors to preferentially target myeloid cells
Singh, S.; Smyth, D. J.; Cunningham, K.; Mukundan, A.; Byron, C.-H.; Hinck, C. S.; White, M. P. J.; Ciancia, C.; Wosowska, N.; Sanders, A.; Jin, R.; Lilla, S.; Zanivan, S.; Schoenherr, C.; Inman, G.; van Dinther, M. A. H.; ten Dijke, P.; Hinck, A. P.; Maizels, R. M.
10.1101/2023.11.13.566701 — immunology — Posted on 2023-11-15
2552 Cell type-specific effects of age and sex on human cortical neurons
Chien, J.-F.; Liu, H.; Wang, B.-A.; Luo, C.; Bartlett, A.; Castanon, R.; Johnson, N. D.; Nery, J. R.; Osteen, J.; Li, J.; Altshul, J.; Kenworthy, M.; Valadon, C.; Liem, M.; Claffey, N.; O'Connor, C.; Seeker, L. A.; Ecker, J. R.; Behrens, M. M.; Mukamel, E. A.
10.1101/2023.11.11.566717 — neuroscience — Posted on 2023-11-15
2553 The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons
Jones-Tabah, J.; He, K.; Senkevich, K.; Karpilovsky, N.; Deyab, G.; Cousineau, Y.; Nikanorova, D.; Goldsmith, T.; del Cid Pellitero, E.; Chen, C. X.-Q.; Luo, W.; You, Z.; Abdian, N.; Pietrantonio, I.; Goiran, T.; Ahmad, J.; Ruskey, J. A.; Asayesh, F.; Spiegelman, D.; Fahn, S.; Waters, C.; Monchi, O.; Dauvilliers, Y.; Dupre, N.; Miliukhina, I.; Timofeeva, A.; Emelyanov, A.; Pchelina, S.; Greenbaum, L.; Hassin-Baer, S.; Alcalay, R. N.; Milnerwood, A.; Durcan, T. M.; Gan-Or, Z.; Fon, E. A.
10.1101/2023.11.11.566693 — neuroscience — Posted on 2023-11-15
2555 Therapeutic targeting of immunometabolism in Alzheimers disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression.
Codocedo, J. F.; Mera Reina, C.; Lin, P. B.-C.; Puntambekar, S. S.; Casali, B. T.; Jury, N.; Martinez, P.; Lasagna-Reeves, C. A.; Landreth, G. E.
10.1101/2023.11.11.566270 — neuroscience — Posted on 2023-11-15
2556 Testing of putative antiseizure drugs in a preclinical Dravet syndrome zebrafish model
Whyte-Fagundes, P.; Vance, A.; Carroll, A.; Figueroa, F.; Manukyan, C.; Baraban, S. C.
10.1101/2023.11.11.566723 — neuroscience — Posted on 2023-11-15
2564 Flexible Perception of Tactile Motion in Multiple Reference Frames
Ahuja, H.; Shivkumar, S.; Feistritzer, C. M.; Haefner, R. M.; DeAngelis, G. C.; Gomez-Ramirez, M.
10.1101/2023.11.10.566625 — neuroscience — Posted on 2023-11-15
2566 Multiplexed 3D Analysis of Cell Plasticity and Immune Niches in Melanoma
Yapp, C.; Nirmal, A. J.; Zhou, F. Y.; Maliga, Z.; Montero Llopis, P.; Murphy, G. F.; Lian, C.; Danuser, G.; Santagata, S.; Sorger, P. K.
10.1101/2023.11.10.566670 — cancer biology — Posted on 2023-11-15
2580 In vivo evaluation of a novel compliance-matching vascular graft
Rovas, G.; Reymond, P.; Van Steenberghe, M.; Diaper, J.; Bikia, V.; Cikirikcioglu, M.; Habre, W.; Huber, C.; Stergiopulos, N.
10.1101/2023.11.10.566623 — bioengineering — Posted on 2023-11-15
2581 Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex
Dubiez, E.; Pellegrini, E.; Finderup Brask, M.; Garland, W.; Foucher, A.-E.; Huard, K.; Jensen, T. H.; Cusack, S.; Kadlec, J.
10.1101/2023.07.25.550453 — biochemistry — Posted on 2023-11-15
2586 Development of LRRK2 designed ankyrin-repeat proteins
Dederer, V.; Sanz Murillo, M.; Karasmanis, E. P.; Hatch, K. S.; Chatterjee, D.; Preuss, F.; Abdul Azeez, K. R.; Nguyen, L. V.; Galicia, C.; Dreier, B.; Pluckthun, A.; Versees, W.; Mathea, S.; Leschziner, A. E.; Reck-Peterson, S. L.; Knapp, S.
10.1101/2023.11.14.567123 — biochemistry — Posted on 2023-11-15
2589 The eIF4A2 negative regulator of mRNA translation promotes extracellular matrix deposition to accelerate hepatocellular carcinoma initiation
Moore, M.; Pardo, L.; Mitchell, L.; Schmidt, T.; Waldron, J.; May, S.; Mueller, M.; Smith, R.; Strathdee, D.; Bryson, S.; Hodge, K.; Lilla, S.; Wilczynska, A.; McGarry, L.; Gillen, S.; Peter-Durairaj, R.; Kanellos, G.; Nixon, C.; Zanivan, S.; Sansom, O. J.; Bird, T.; Bushell, M.; Norman, J. C.
10.1101/2023.08.16.553544 — cancer biology — Posted on 2023-11-15
2590 3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes
Scudese, E.; Vue, Z.; Katti, P.; Marshall, A.; Vang, L.; Garza Lopez, E.; Neikirk, K.; Stephens, D.; Hall, D. D.; Rostami, R.; Shao, J.-q.; Mungai, M.; AshShareef, S.; Hicsasmaz, I.; Manus, S.; Whiteside, A.; Williams, C.; Damo, S.; Gaddy, J.; Kirabo, A.; Glancy, B.; Henrique Martin Dantas, E.; Kinder, A.; Scartoni, F.; Baffi, M.; McReynolds, M.; Wanjalla, C. N.; Phillips, M. A.; Exil, V.; Mobley, B.; Hinton, A.
10.1101/2023.11.13.566502 — biophysics — Posted on 2023-11-15
2591 Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge
Grunst, M. W.; Gil, H. M.; Grandea, A. G.; Snow, B. J.; Andrabi, R.; Nedellec, R.; Burton, I.; Clark, N. M.; Janaka, S. K.; Keles, N. K.; Moriarty, R. V.; Weiler, A. M.; Capuano, S.; Fennessey, C. M.; Friedrich, T. C.; O'Connor, S. L.; O'Connor, D. H.; Broman, A. T.; Keele, B. F.; Lifson, J. D.; Hangartner, L.; Burton, D. R.; Evans, D. T.
10.1101/2023.11.14.567003 — microbiology — Posted on 2023-11-15
2592 Conformational Dynamics in Aptamer Modulate Neurotransmitter Sensing in Nanopores
Stuber, A.; Douaki, A.; Hengsteler, J.; Buckingham, D.; Momotenko, D.; Garoli, D.; Nakatsuka, N.
10.1101/2023.03.10.532011 — neuroscience — Posted on 2023-11-15
2596 The Arabidopsis SR45 splicing factor bridges the splicing machinery and the exon-exon junction complex
Fanara, S.; Schloesser, M.; Joris, M.; De Franco, S.; Vandevenne, M.; Kerff, F.; Hanikenne, M.; Motte, P.
10.1101/2023.08.07.552250 — plant biology — Posted on 2023-11-15
2597 Identification of genes with oscillatory expression in glioblastoma: The paradigm of SOX2
Fu, R. Z.; Cottrell, O.; Cutillo, L.; Rowntree, A.; Zador, Z.; Wurdak, H.; Papalopulu, N.; Marinopoulou, E.
10.1101/2023.11.12.566579 — cancer biology — Posted on 2023-11-15
2598 GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.
Chaudhary, N.; Choudhary, B. S.; Patra, S.; Malvankar, S.; Shivashankar, A.; Jog, E.; Kailaje, V. K.; Khanna, S.; Manna, S.; Sahoo, S.; R, S.; Jolly, M. K.; Dalal, S. N.; Verma, N.
10.1101/2023.05.18.541287 — cancer biology — Posted on 2023-11-15
2602 Identifying genetic variants that influence the abundance of cell states in single-cell data
Rumker, L.; Sakaue, S.; Reshef, Y.; Kang, J. B.; Yazar, S.; Alquicira-Hernandez, J.; Valencia, C.; Lagattuta, K. A.; Mah-Som, A.; Nathan, A.; Powell, J. E.; Loh, P.-R.; Raychaudhuri, S.
10.1101/2023.11.13.566919 — genetics — Posted on 2023-11-15
2606 Logging alters tropical forest structure, while conversion reduces biodiversity and functioning
Marsh, C. J.; Turner, E. C.; Blonder, B. W.; Bongalov, B.; Both, S.; Cruz, R. S.; Elias, D. M. O.; Hemprich-Bennett, D.; Jotan, P.; Kemp, V.; Kritzler, U. H.; Milne, S.; Milodowski, D. T.; Mitchell, S. L.; Montoya Pillco, M.; Nunes, M. H.; Riutta, T.; Robinson, S. J. B.; Slade, E. M.; Bernard, H.; Burslem, D. F. R. P.; Chung, A. Y. C.; Clare, E. L.; Coomes, D. A.; Davies, Z. G.; Edwards, D. P.; Johnson, D.; Kratina, P.; Malhi, Y.; Majalap, N.; Nilus, R.; Ostle, N. J.; Rossiter, S. J.; Struebig, M. J.; Tobias, J. A.; Williams, M.; Ewers, R. M.; Lewis, O. T.; Reynolds, G.; Teh, Y. A.; Hector, A.
10.1101/2022.12.15.520573 — ecology — Posted on 2023-11-15
2609 Algal Exudates Promote Conjugation in Marine Roseobacters
Duchin Rapp, Y.; Yuda, L.; Matsliyah, D.; Kublanov, I. V.; Segev, E.
10.1101/2023.11.14.567099 — microbiology — Posted on 2023-11-15
2616 Advancing Cell Therapies: Single-Cell Profiling, Generation, Expansion, and Gene Delivery in Rhesus Macaque Plasma B Cells
Cheng, R. Y.-H.; Kreuser, S.; Dahl, N.; Honaker, Y.; Soligalla, R.; Lopez, C.; Rawlings, D. J.; James, R. G.
10.1101/2023.10.29.564645 — bioengineering — Posted on 2023-11-14
2621 Structural basis for VLDLR recognition by eastern equine encephalitis virus
Yang, P.; Li, W.; Fan, X.; Pan, J.; Mann, C. J.; Varnum, H.; Clark, L. E.; Clark, S. A.; Coscia, A.; Smith, K. N.; Brusic, V.; Abraham, J.
10.1101/2023.11.14.567065 — microbiology — Posted on 2023-11-14
2622 Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells
Kath, J.; Franke, C.; Drosdek, V.; Du, W.; Glaser, V.; Fuster-Garcia, C.; Stein, M.; Zittel, T.; Schulenberg, S.; Porter, C. E.; Andersch, L.; Kuenkele, A.; Alcaniz, J.; Hoffmann, J.; Abken, H.; Abou-el-Enein, M.; Pruss, A.; Suzuki, M.; Cathomen, T.; Stripecke, R.; Volk, H.-D.; Reinke, P.; Schmueck-Henneresse, M.; Wagner, D. L.
10.1101/2023.11.10.565518 — immunology — Posted on 2023-11-14
2624 Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers
Rose, K. N.; Zorlu, M.; Xue, X.; Fassini, A.; Cai, W.; Lin, S.; Webb, P. K.; Schwarzschild, M.; Chen, X.; Gomperts, S. N.
10.1101/2023.05.27.542565 — neuroscience — Posted on 2023-11-14
2625 Prediction of plant complex traits via integration of multi-omics data
Wang, P.; Lehti-Shiu, M. D.; Lotreck, S.; Segura Aba, K.; Shiu, S.-H.
10.1101/2023.11.14.566971 — bioinformatics — Posted on 2023-11-14
2631 Chaotic signatures in host-microbe interactions
Sella, Y.; Broderick, N. A.; Stouffer, K.; McEwan, D. L.; Ausubel, F. M.; Casadevall, A.; Bergman, A.
10.1101/2022.12.14.520402 — microbiology — Posted on 2023-11-14
2632 Combinatorial control of biofilm development by quorum-sensing and nutrient-sensing regulators in Pseudomonas aeruginosa
Chen, G.; Fanouraki, G.; Anandhi Rangarajan, A.; Winkelman, B. T.; Winkelman, J. T.; Waters, C. M.; Mukherjee, S.
10.1101/2022.09.27.509822 — microbiology — Posted on 2023-11-14
2634 Levetiracetam Modulates Brain Metabolic Networks and Transcriptomic Signatures in the 5XFAD Mouse Model of Alzheimer's disease.
Burton, C. P.; Chumin, E. J.; Collins, A. Y.; Pandey, R. S.; Persohn, S. A.; Quinney, S. K.; Pandey, R. S.; Onos, K. D.; Territo, P. R.
10.1101/2023.11.10.566574 — neuroscience — Posted on 2023-11-14
2635 Proteome-wide base editor screens to assess phosphorylation site functionality in high-throughput
Kennedy, P. H.; Deh Sheikh, A. A.; Balakar, M.; Jones, A. C.; Olive, M. E.; Hedge, M.; Matias, M. I.; Pirete, N.; Burt, R.; Levy, J.; Little, T.; Hogan, P. G.; Liu, D. R.; Doench, J. G.; Newton, A. C.; Gottschalk, R. A.; de Boer, C.; Alarcon, S.; Newby, G.; Myers, S. A.
10.1101/2023.11.11.566649 — systems biology — Posted on 2023-11-14
2638 Engineering synthetic phosphorylation signaling networks in human cells
Yang, X.; Rocks, J. W.; Jiang, K.; Walters, A. J.; Rai, K.; Liu, J.; Nguyen, J.; Olson, S. D.; Mehta, P.; Collins, J. J.; Daringer, N. M.; Bashor, C. J.
10.1101/2023.09.11.557100 — synthetic biology — Posted on 2023-11-14
2640 Melanoma-derived DNA polymerase theta variants exhibit altered DNA polymerase activity
Thomas, C.; Avalos-Irving, L.; Victorino, J.; Green, S.; Andrews, M.; Rodrigues, N.; Ebirim, S.; Mudd, A.; Towle-Weicksel, J. B.
10.1101/2023.11.14.566933 — biochemistry — Posted on 2023-11-14
2648 Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms
Bond, A.; Fiaz, S.; Rollins, K. R.; Nario, J. E. Q.; Rosen, S. J.; Granados, A.; Wilson, M. Z.; Morrissey, M. A.
10.1101/2023.11.14.567059 — cell biology — Posted on 2023-11-14
2650 Circadian Control of Histone Turnover During Cardiac Development and Growth
Arrieta, A.; Chapski, D. J.; Reese, A.; Kimball, T. H.; Song, K.; Rosa-Garrido, M.; Vondriska, T. M.
10.1101/2023.11.14.567086 — molecular biology — Posted on 2023-11-14
2652 Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades
Dadonaite, B.; Brown, J.; McMahon, T. E.; Farrell, A. G.; Asarnow, D.; Stewart, C.; Logue, J.; Murrell, B.; Chu, H. Y.; Veesler, D.; Bloom, J. D.
10.1101/2023.11.13.566961 — microbiology — Posted on 2023-11-14
2653 Emergence of the Novel Infectious bursal disease viruse Variant in Vaccinated Poultry Flocks in Egypt
Shahin, M. A.; Sultan, H. A.; Zanaty, A.; Mosaad, Z.; Hagage, N. M.; Adel, A.; Selim, K.; Saied, D.; Samir, A. H.; Erfan, A.; Arafa, A.; Selim, A.; Samy, M.; Naguib, M. M.; Hassan, H.; El Shazly, O.; Elbade, Z. A.; Kamel, M.; Farghaly, E.; Eid, S.; El Shahaby, M.; Hammoda, M.; Mehana, O.; Nabeh, M.; Samy, A.
10.1101/2023.11.13.566865 — microbiology — Posted on 2023-11-14
2654 Algal Exudates Promote Conjugation in Marine Roseobacters
Segev, E.; Duchin Rapp, Y.; Yuda, L.; Matsliyah, D.; Kublanov, I. V.
10.1101/2023.11.14.567099 — microbiology — Posted on 2023-11-14
2655 Characterization of the Entner-Douderoff Pathway in Pseudomonas aeruginosa Catheter-associated Urinary Tract Infections
El Husseini, N.; Mekonnen, S. A.; Hall, C. L.; Cole, S. J.; Carter, J. A.; Belew, A. T.; El-Sayed, N. M.; Lee, V. T.
10.1101/2023.11.14.567044 — microbiology — Posted on 2023-11-14
2656 The Velvet transcription factor PnVeA regulates necrotrophic effectors and secondary metabolism in the wheat pathogen Parastagonospora nodorum
Morikawa, S.; Verdonk, C.; John, E.; Lenzo, L.; Sbaraini, N.; Turo, C. J.; Li, H.; Jiang, D.; Chooi, Y.-H.; Tan, K.-C.
10.1101/2023.11.13.566949 — microbiology — Posted on 2023-11-14
2657 ST8Sia2 polysialyltransferase protects against infection by Trypanosoma cruzi
Barboza, B. R.; da Silva, J. M.; Trajano-Silva, L. A. M.; Gomes, V. d. M.; Santos, D. M.; Marques-Neto, A. M.; Mule, S. N.; Borsoi, J.; Moraes, C. B.; Muhlenhoff, M.; Colli, W.; Marie, S. K. N.; Pereira, L. V.; Alves, M. J. M.; Palmisano, G.
10.1101/2023.11.14.567071 — microbiology — Posted on 2023-11-14
2658 FeLIX is a restriction factor for mammalian retrovirus infection
Pramono, D.; Takeuchi, D.; Katsuki, M.; AbuEed, L.; Abdillah, D.; Kimura, T.; Kawasaki, J.; Miyake, A.; Nishigaki, K.
10.1101/2023.11.14.567074 — microbiology — Posted on 2023-11-14
2663 Diurnal rhythm causes metabolic crises in the cyanobacterial mutants of c-di-AMP signalling cascade
Haffner, M.; Mantovani, O.; Spaet, P.; Macek, B.; Hagemann, M.; Forchhammer, K.; Selim, K. A.
10.1101/2023.11.14.567006 — microbiology — Posted on 2023-11-14
2664 SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells
Abrozek-Latecka, M.; Kozlowski, P.; Hoser, G.; Bandyszewska, M.; Hanusek, K.; Nowis, D.; Golab, J.; Grzanka, M.; Piekielko-Witkowska, A.; Schulz, L.; Hornung, F.; Deinhardt-Emmer, S.; Kozlowska, E.; Skirecki, T.
10.1101/2023.11.13.566917 — immunology — Posted on 2023-11-14
2668 CodonBERT: Large Language Models for mRNA Design and Optimization
Li, S.; Moayedpour, S.; Li, R.; Bailey, M.; Riahi, S.; Kogler-Anele, L.; Miladi, M.; Miner, J.; Zheng, D.; Wang, J.; Balsubramani, A.; Tran, K.; Zacharia, M.; Wu, M.; Gu, X.; Clinton, R.; Asquith, C.; Skaleski, J.; Boeglin, L.; Chivukula, S.; Dias, A.; Montoya, F. U.; Agarwal, V.; Bar-Joseph, Z.; Dr. Jager, S.
10.1101/2023.09.09.556981 — bioinformatics — Posted on 2023-11-14
2670 A double-ring of human RAD52 remodels replication forks restricting fork reversal
Honda, M.; Razzaghi, M.; Gaur, P.; Malacaria, E.; Di Biagi, L.; Aiello, F. A.; Paintsil, E. A.; Stanfield, A.; Deppe, B. J.; Gakhar, L.; Schnicker, N. J.; Spies, M. A.; Pichierri, P.; Spies, M.
10.1101/2023.11.14.566657 — biochemistry — Posted on 2023-11-14
2674 The effect of antibiotic selection on collateral effects and evolvability of uropathogenic Escherichia coli
James, B. A.; Reesaul, H.; Kashif, S.; Behruznia, M.; Meehan, C. J.; Domingo Sananes, M. R.; Hubbard, A. T. M.
10.1101/2023.11.14.567005 — microbiology — Posted on 2023-11-14
2675 SHIELD: Skull-shaped hemispheric implants enabling large-scale-electrophysiology datasets in the mouse brain
Bennett, C.; Ouellette, B.; Ramirez, T. K.; Cahoon, A.; Cabasco, H.; Belski, H.; Gillis, R.; Grasso, C.; Howard, R.; Johnson, T.; Loeffler, H.; Smith, H.; Sullivan, D.; Williford, A.; Caldejon, S.; Durand, S.; Gale, S. D.; Guthrie, A.; Ha, V.; Han, W.; Hardcastle, B.; McBride, E.; Mochizuki, C.; Sridhar, A.; Suarez, L.; Swapp, J.; Wilkes, J.; Farrell, C.; Groblewski, P.; Olsen, S.
10.1101/2023.11.12.566771 — neuroscience — Posted on 2023-11-14
2677 A multiscale approach to investigate fluorescence and NDVI imaging as proxy of photosynthetic traits in wheat
Virlet, N.; Pennacchi, J. P.; Sadeghi-Tehran, P.; Ashfield, T.; Orr, D.; Carmo-Silva, E.; Hawkesford, M.
10.1101/2023.11.10.566533 — plant biology — Posted on 2023-11-14
2678 Plant pathogenic fungi hijack phosphate starvation signaling with conserved enzymatic effectors
McCombe, C. L.; Wegner, A.; Zamora, C. S.; Casanova, F.; Aditya, S.; Greenwood, J. R.; Wirtz, L.; de Paula, S.; England, E.; Shang, S.; Ericsson, D. J.; Oliveira-Garcia, E.; Williams, S. J.; Schaffrath, U.
10.1101/2023.11.14.566975 — plant biology — Posted on 2023-11-14
2679 Evidence that variation in root anatomy contributes to local adaptation in Mexican native maize
McLaughlin, C.; Li, M.; Perryman, M.; Heymans, A.; Schneider, H.; Lasky, J.; Sawers, R.
10.1101/2023.11.14.567017 — plant biology — Posted on 2023-11-14
2680 Primary multistep phosphorelay activation comprises both cytokinin and abiotic stress responses in Brassicaceae
Nicolas Mala, K. L.; Skalak, J.; Zemlyanskaya, E.; Dolgikh, V.; Jedlickova, V.; Robert-Boisivon, H.; Havlickova, L.; Panzarova, K.; Trtilek, M.; Bancroft, I.; Hejatko, J.
10.1101/2023.11.14.567013 — plant biology — Posted on 2023-11-14
2683 Transcriptomic landscape of seedstick in Arabidopsis thaliana funiculus after fertilisation
Ferreira, M. J.; Silva, J.; Takeuchi, H.; Suzuki, T.; Higashiyama, T.; Coimbra, S. V. d. A.
10.1101/2023.11.13.566818 — plant biology — Posted on 2023-11-14
2688 Characterization of a Novel Mouse Platelet Transfusion Model
Gordy, D.; Swayne, T.; Berry, G. J.; Thomas, T. A.; Hudson, K. E.; Stone, E. F.
10.1101/2023.11.10.566577 — pathology — Posted on 2023-11-14
2691 Sleep Disruption in a Mouse Model of Chronic Traumatic Brain Injury
Morris, A. R.; Gudenschwager Basso, E. K.; Gutierrez-Monreal, M. A.; Arja, R. D.; Kobeissy, F. H.; Janus, C. G.; Wang, K. K.; Zhu, J.; Liu, A. C.
10.1101/2023.11.10.566553 — neuroscience — Posted on 2023-11-14
2692 Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence
Nguyen, T. D.; Rao, M. K.; Dhyani, S. P.; Banks, J. M.; Winek, M. A.; Michalkiewicz, J.; Lee, M. Y.
10.1101/2023.11.10.566598 — physiology — Posted on 2023-11-14
2694 E2F transcription factors promote tumorigenicity in pancreatic ductal adenocarcinoma
Bertonnier-Brouty, L.; Andersson, J.; Kaprio, T.; Hagstrom, J.; Bsharat, S.; Asplund, O.; Hatem, G.; Haglund, C.; Seppanen, H.; Prasad, R. B.; Artner, I.
10.1101/2023.11.10.566445 — cancer biology — Posted on 2023-11-14
2697 Chemical Tools for the Gid4 Subunit of the Human E3 Ligase C-terminal to LisH (CTLH) Degradation Complex
Yazdi, A. K.; Perveen, S.; Song, X.; Dong, A.; Szewczyk, M.; Calabrese, M.; Casimiro-Garcia, A.; Subramanyam, C.; Dowling, M. S.; Ficici, E.; Lee, J.; Montgomery, J. I.; O'Connell, T. N.; Skrzypek, G. J.; Tran, T. P.; Troutman, M. D.; Wang, F.; Young, J. A.; Min, J.; Barsyte-Lovejoy, D.; Brown, P. J.; Santhakumar, V.; Arrowsmith, C.; Vedadi, M.; Owen, D. R.
10.1101/2023.11.13.566858 — biophysics — Posted on 2023-11-14
2701 Impact of central carbon metabolism bypasses on the production of beta-carotene in Yarrowa lipolytica
Markus, T.; Soldat, M.; Magdevska, V.; Horvat, J.; Kavscek, M.; Kosec, G.; Fujs, S.; Petrovic, U.
10.1101/2023.11.10.566616 — bioengineering — Posted on 2023-11-14
2703 The cell cycle controls spindle architecture in Arabidopsis by modulating the augmin pathway
Motta, M. R.; Nedelec, F.; Woelken, E.; Saville, H.; Jacquerie, C.; Pastuglia, M.; Stolze, S. C.; Van De Slijke, E.; Chen, P.; Boettger, L.; Belcram, K.; Nakagami, H.; De Jaeger, G.; Bouchez, D.; Schnittger, A.
10.1101/2023.11.14.567058 — developmental biology — Posted on 2023-11-14
2706 Disruption of IL-17 signaling in the respiratory mucosa results in invasive streptococcal infection
Pandey, M.; Mills, J.-L.; Lepletier, A.; Ozberk, V.; Dooley, J.; Kaden, J.; Calcutt, A.; Huo, Y.; Hicks, A.; Zaid, A.; Good, M.
10.1101/2023.11.10.566548 — immunology — Posted on 2023-11-14
2709 Lateral inhibition in V1 controls neural & perceptual contrast sensitivity
Del Rosario, J.; Coletta, S.; Kim, S. H.; Mobille, Z.; Peelman, K.; Williams, B.; Otsuki, A. J.; Del Castillo Valerio, A.; Worden, K.; Blanpain, L. T.; Lovell, L.; Choi, H.; Haider, B.
10.1101/2023.11.10.566605 — neuroscience — Posted on 2023-11-14
2711 PriOmics: integration of high-throughput proteomic data with complementary omics layers using mixed graphical modeling with group priors
Kosch, R.; Limm, K.; Staiger, A. M.; Kurz, N. S.; Seifert, N.; Olah, B.; Solbrig, S.; Ziepert, M.; Chteinberg, E.; Spang, R.; Siebert, R.; Zacharias, H. U.; Ott, G.; Oefner, P. J.; Altenbuchinger, M.
10.1101/2023.11.10.566517 — systems biology — Posted on 2023-11-14
2714 SpatialCells: Automated Profiling of Tumor Microenvironments with Spatially Resolved Multiplexed Single-Cell Data
Wan, G.; Maliga, Z.; Yan, B.; Vallius, T.; Shi, Y.; Khattab, S.; Chang, C.; Nirmal, A. J.; Yu, K.-H.; Liu, D.; Lian, C. G.; DeSimone, M. S.; Sorger, P. K.; Semenov, Y. R.
10.1101/2023.11.10.566378 — bioinformatics — Posted on 2023-11-14
2716 Prior Fc Receptor activation primes macrophage for increased sensitivity to IgG via long term and short term mechanisms
Bond, A.; Fiaz, S.; Rollins, K. R.; Nario, J. E. Q.; Rosen, S. J.; Granados, A.; Wilson, M. Z.; Morrissey, M. A.
10.1101/2023.11.14.567059 — cell biology — Posted on 2023-11-14
2720 tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory
Madhwani, K. R.; Sayied, S.; Ogata, C. H.; Hogan, C. A.; Lentini, J. M.; Mallik, M.; Dumouchel, J. L.; Storkebaum, E.; Fu, D.; O'Connor-Giles, K. M.
10.1101/2023.11.14.566895 — cell biology — Posted on 2023-11-14
2721 Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
Zurawska, G.; Sas, Z.; Jonczy, A.; Slusarczyk, P.; Mahadeva, R.; Chwalek, M.; Kulecka, M.; Rumienczyk, I.; Moulin, M.; Jastrzebski, K.; Mikula, M.; Etzerodt, A.; Miaczynska, M.; Rygiel, T. P.; Mleczko-Sanecka, K.
10.1101/2023.11.14.566925 — cell biology — Posted on 2023-11-14
2722 A NRF2/beta3-adrenoreceptor axis drives a sustained antioxidant and metabolic rewiring through the pentose-phosphate pathway to alleviate cardiac stress
Michel, L.; Esfahani, H.; Verdoy, R.; de Mulder, D.; Ambroise, J.; Roelants, V.; Bouchard, B.; Savary, J.; Dewulf, J.; Doumont, T.; Bouzin, C.; Haufroid, V.; Luiken, J. J. F. P.; Nabben, M.; Singleton, M.; Bertrand, L.; Ruiz, M.; Des Rosiers, C.; Balligand, J.-L.
10.1101/2023.11.10.564735 — physiology — Posted on 2023-11-14
2723 Aberrant splicing exonizes C9ORF72 repeat expansion in ALS/FTD
Yang, S.; Wijegunawardana, D.; Sheth, U.; Veire, A.; Salgado, J. M. S.; Agrawal, M.; Zhou, J.; Pereira, J. D.; Gendron, T. F.; Guo, J. U.
10.1101/2023.11.13.566896 — neuroscience — Posted on 2023-11-14
2724 Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer's Disease Model
Rao, A.; Chen, N.; Kim, M. J.; Blumenfeld, J.; Yip, O.; Hao, Y.; Liang, Z.; Nelson, M. R.; Koutsodendris, N.; Grone, B.; Ding, L.; Yoon, S. Y.; Arriola, P.; Huang, Y.
10.1101/2023.11.10.566510 — neuroscience — Posted on 2023-11-14
2725 State-dependent alteration of respiration in a rat model of Parkinson disease
Walker, J. J.; Meunier, E.; Garcia, S.; Messaoudi, B.; Mouly, A.-M.; Veyrac, A.; Buonviso, N.; Courtiol, E.
10.1101/2023.11.10.566528 — neuroscience — Posted on 2023-11-14
2726 MITF regulates IDH1 and NNT and drives a transcriptional program protecting cutaneous melanoma from reactive oxygen species
Roider, E.; Lakatos, A. I. T.; McConnell, A. M.; Wang, P.; Mueller, A.; Kawakami, A.; Tsoi, J.; Szabolcs, B. L.; Ascsillan, A. A.; Suita, Y.; Igras, V.; Lo, J. A.; Hsiao, J. J.; Lapides, R.; Pal, D. M. P.; Lengyel, A. S.; Navarini, A.; Okazaki, A.; Iliopoulos, O.; Nemeth, I.; Graeber, T. G.; Zon, L.; Giese, R. W.; Kemeny, L. V.; Fisher, D. E.
10.1101/2023.11.10.564582 — cancer biology — Posted on 2023-11-14
2729 Neural interactions in the human frontal cortex dissociate reward and punishment learning
Combrisson, E.; Basanisi, R.; Gueguen, M.; Rheims, S.; Kahane, P.; Bastin, J.; Brovelli, A.
10.1101/2023.05.02.539138 — neuroscience — Posted on 2023-11-14
2731 Pathogen community composition and co-infection patterns in a wild community of rodents
Abbate, J. L.; Galan, M.; Razzauti, M.; Sironen, T.; Voutilainen, L.; Henttonen, H.; Gasqui, P.; Cosson, J.-F.; Charbonnel, N.
10.1101/2020.02.09.940494 — ecology — Posted on 2023-11-14
2732 Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches.
Carter, J.; Walker, T. M.; Walker, A. S.; Whitfield, M.; Morlock, G. P.; Lynch, C. I.; Adlard, D.; Peto, T. E.; Posey, J. E.; Crook, D. W.; Fowler, P. W.
10.1101/518142 — microbiology — Posted on 2023-11-14
2733 Mycobiome analyses of critically ill COVID-19 patients
Weaver, D.; Gago, S.; Bassetti, M.; Giacobbe, D. R.; Prattes, J.; Hoenigl, M.; Reizine, F.; Guegan, H.; Gangneux, J.-P.; Bromley, M. J.; Bowyer, P.
10.1101/2023.06.13.543274 — microbiology — Posted on 2023-11-14
2734 A visual paired associate learning (vPAL) paradigm to study memory consolidation during sleep
Schmidig, F. J.; Geva-Sagiv, M.; Falach, R.; Yakim, S.; Gat, Y.; Sharon, O.; Fried, I.; Nir, Y.
10.1101/2023.03.28.534494 — neuroscience — Posted on 2023-11-14
2736 Scots pine - panmixia and the elusive signal of genetic adaptation
Bruxaux, J.; Zhao, W.; Hall, D.; Curtu, A. L.; Androsiuk, P.; Drouzas, A. D.; Gailing, O.; Konrad, H.; Sullivan, A. R.; Semerikov, V.; Wang, X.-R.
10.1101/2023.06.09.543371 — evolutionary biology — Posted on 2023-11-14
2737 Pan-genome study underlining the extent of genomic variation of invasive Streptococcus pneumoniae in Malawi
Iranzadeh, A.; Alisoltani, A.; Kiran, A.; Breiman, R.; Chaguza, C.; Peno, C.; Cornick, J. E.; Everett, D. B.; Mulder, N.
10.1101/2023.01.02.522535 — microbiology — Posted on 2023-11-14
2738 Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers, followed by engulfment by microglia
Francis, V.; Liddle, C.; Camacho, E.; Kulkarni, M.; Junior, S. R.; Harvey, J. A.; Ballou, E. R.; Thomson, D. D.; Hardwick, J. M.; Casadevall, A.; Witton, J.; Coelho, C.
10.1101/2023.11.13.564824 — microbiology — Posted on 2023-11-14
2740 Astrocytes gate long-term potentiation in hippocampal interneurons
Shen, W.; Tang, Y.; Yang, J.; Zhu, L.; Zhou, W.; Xiang, L.; Zhu, F.; Dong, J.; Xie, Y.; Zeng, L.-H.
10.1101/2023.06.20.545820 — neuroscience — Posted on 2023-11-14
2743 Impaired migration and metastatic spread of human melanoma by a novel small molecule targeting the transmembrane domain of death receptor p75NTR
Lopes-Rodrigues, V.; Nyantakyi, S. A.; Lun, X.; Zhang, J.; Ramanujuan, A.; Salim, S.; Saleeb, M.; Senger, D. L.; Ibanez, C. F.
10.1101/2023.11.13.566904 — cancer biology — Posted on 2023-11-14
2745 GENTANGLE: integrated computational design of gene entanglements
Marti, J. M.; Hsu, C.; Rochereau, C.; Blazejewski, T.; Nisonoff, H.; Leonard, S. P.; Kang-Yun, C. S.; Chlebek, J. L.; Ricci, D. P.; Park, D. M.; Wang, H. H.; Listgarten, J.; Jiao, Y.; Allen, J. E.
10.1101/2023.11.09.565696 — bioinformatics — Posted on 2023-11-14
2746 A single-cell atlas of transcribed cis-regulatory elements in the human genome
Moody, J.; Kouno, T.; Kojima, M.; Koya, I.; Leon, J.; Suzuki, A.; Hasegawa, A.; Akiyama, T.; Akiyama, N.; Amagai, M.; Chang, J.-C.; Fukushima-Nomura, A.; Handa, M.; Hino, K.; Hino, M.; Hirata, T.; Imai, Y.; Inoue, K.; Kawasaki, H.; Kimura, T.; Kinoshita, T.; Kubo, K.-i.; Kunii, Y.; Lopez-Redondo, F.; Manabe, R.-i.; Miyai, T.; Morimoto, S.; Nagaoka, A.; Nakajima, J.; Noma, S.; Okazaki, Y.; Ozaki, K.; Saeki, N.; Sakai, H.; Seyama, K.; Shibayama, Y.; Sujino, T.; Tagami, M.; Takahashi, H.; Takao, M.; Takeshita, M.; Takiuchi, T.; Terao, C.; Yip, C. W.; Yoshinaga, S.; Okano, H.; Yamamoto, K.; Kasuka
10.1101/2023.11.13.566791 — genomics — Posted on 2023-11-14
2747 Transcriptomic reprogramming screen identifies SRSF1 as rejuvenation factor
Plesa, A. M.; Jung, S.; Wang, H. H.; Omar, F.; Shadpour, M.; Choy Buentello, D.; Perez-Matos, M. C.; Horwitz, N.; Cai, G.; Ngian, Z.-K.; de Magalhaes, C. V.; Wagers, A. J.; Mair, W. B.; del Sol Mesa, A.; Church, G. M.
10.1101/2023.11.13.566787 — genomics — Posted on 2023-11-14
2750 Efficient workflow for validating homology-independent targeted integration-mediated gene insertion in rod photoreceptor cells to treat dominant-negative mutations causing retinitis pigmentosa
Onishi, A.; Tsunekawa, Y.; Mandai, M.; Ishimaru, A.; Ohigashi, Y.; Sho, J.; Yasuda, K.; Suzuki, K.; Izpisua Belmonte, J. C.; Matsuzaki, F.; Takahashi, M.
10.1101/2023.11.08.566127 — molecular biology — Posted on 2023-11-14
2751 Crosstalk of platelets with macrophages and fibroblasts aggravates inflammation, aortic wall stiffening, and osteopontin release in abdominal aortic aneurysm
Wagenhaeuser, M. U.; Mulorz, J.; Krott, K. J.; Bosbach, A.; Feige, T.; Rhee, Y. H.; Chatterjee, M.; Petzold, N.; Boeddeker, C.; Ibing, W.; Krueger, I.; Popovic, A. M.; Roseman, A.; Spin, J. M.; Tsao, P. S.; Schelzig, H.; Elvers, M.
10.1101/2022.12.01.518674 — molecular biology — Posted on 2023-11-14
2753 Neonatal brain dynamic functional connectivity in term and preterm infants and its association with early childhood neurodevelopment
Franca, L. G. S.; Ciarrusta, J.; Gale-Grant, O.; Fenn-Moltu, S.; Fitzgibbon, S. P.; Chew, A.; Falconer, S.; Dimitrova, R.; Cordero-Grande, L.; Price, A. N.; Hughes, E.; O'Muircheartaigh, J.; Duff, E.; Tuulari, J. J.; Deco, G.; Counsell, S. J.; Hajnal, J. V.; Nosarti, C.; Arichi, T.; Edwards, D.; McAlonan, G.; Batalle, D.
10.1101/2022.11.16.516610 — neuroscience — Posted on 2023-11-14
2755 NBR1-mediated selective autophagy of ARF7 modulates root branching
Ebstrup, E.; Ansboel, J.; Garcia, A. P.; Culp, H.; Chevalier, J.; Clemmens, P.; Coll, N. S.; Moreno-Risueno, M. A.; Rodriguez, E.
10.1101/2022.08.19.504407 — plant biology — Posted on 2023-11-14
2757 Oral contraceptives reduce the avoidance bias to social threat signals
Thurley, J.; Buades Rotger, M.; Serfling, G.; Howaldt, T.; Reisch, N.; Kramer, U. M.
10.1101/2023.11.13.566589 — neuroscience — Posted on 2023-11-14
2758 Multi-timescale reinforcement learning in the brain
Masset, P.; Tano, P.; Kim, H. R.; Malik, A. N.; Pouget, A.; Uchida, N.
10.1101/2023.11.12.566754 — neuroscience — Posted on 2023-11-14
2761 Extreme distributions in the preconfigured developing brain
Chini, M.; Hnida, M.; Kostka, J. K.; Chen, Y.-N.; Hanganu-Opatz, I. L.
10.1101/2023.11.13.566810 — neuroscience — Posted on 2023-11-14
2764 Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain
Hunter, O.; Talkish, J.; Quick-Cleveland, J.; Igel, H.; Tan, A.; Kuersten, S.; Katzman, S.; Donohue, J. P.; Jurica, M. S.; Ares, M.
10.1101/2023.10.05.560965 — molecular biology — Posted on 2023-11-13
2765 A familial missense variant in the Alzheimer's Disease gene SORL1 impairs its maturation and endosomal sorting.
Fazeli, E.; Child, D. D.; Bucks, S. A.; Stovarsky, M.; Edwards, G.; Rose, S.; Yu, C.-E.; Latimer, C.; Kitago, Y.; Bird, T.; Jayadev, S.; Andersen, O.; Young, J. E.
10.1101/2023.07.01.547348 — neuroscience — Posted on 2023-11-13
2774 A reference genome for the Andean cavefish Trichomycterus rosablanca (Siluriformes, Trichomycteridae): building genomic resources to study evolution in cave environments
Cadena, D.; Pabon, L.; DoNascimiento, C.; Abueg, L.; Tiley, T.; O-Toole, B.; Absolon, D.; Sims, Y.; Formenti, G.; Fedrigo, O.; Jarvis, E.; Torres, M.
10.1101/2023.11.11.566715 — genomics — Posted on 2023-11-13
2777 Phylogenomics reveals a gene flow history of reverse colonization
Aoki, D.; Senzaki, M.; Ando, H.; Odaya, Y.; Heim, W.; Kitazawa, M.; Tom, W.; Trense, D.; Bastardot, M.; Fukuda, A.; Takahashi, M.; Kondo, N.
10.1101/2023.09.27.559751 — evolutionary biology — Posted on 2023-11-13
2781 Amplification of avian influenza viruses along poultry marketing chains in Bangladesh: a controlled field experiment
Kohnle, L.; Das, T.; Uddin, M. H.; Nath, S. C.; Mohsin, M. A. S.; Mahmud, R.; Biswas, P. K.; Hoque, M. A.; Pfeiffer, D. U.; Fournie, G.
10.1101/2023.11.10.566573 — ecology — Posted on 2023-11-13
2784 The evolutionary age-range size relationship is modulated by insularity and dispersal in plants and animals
Alzate, A.; Rozzi, R.; Velasco, J. A.; Robertson, D. R.; Zizka, A.; Tobias, J. A.; Hill, A.; Bacon, C. D.; Janzen, T.; Pellissier, L.; van der Plas, F.; Rosindell, J.; Onstein, R. E.
10.1101/2023.11.11.566377 — ecology — Posted on 2023-11-13
2786 AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
Houston, B. J.; Nguyen, J.; Merriner, D. J.; O'Connor, A. E.; Lopes, A. M.; Nagirnaja, L.; Friedrich, C.; Kliesch, S.; Tuettelmann, F.; Aston, K. I.; Conrad, D.; Hobbs, R. M.; Dunleavy, J. E.; O'Bryan, M. K.
10.1101/2023.11.02.565050 — cell biology — Posted on 2023-11-13
2789 S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice
Gruel, R. C. L. P.; Bijnens, B.; Van Den Daele, J.; Thys, S.; Willems, R.; Wuyts, D.; Van Dam, D.; Verstraelen, P.; Verboven, R.; Roels, J.; Vandamme, N.; Mancuso, R.; Pita-Almenar, J. D.; De Vos, W.
10.1101/2023.11.10.566543 — neuroscience — Posted on 2023-11-13
2792 Annotation-Free Deep Learning for Predicting Gene Mutations from Whole Slide Images of Acute Myeloid Leukemia
Wei, B.-H.; Tsai, X. C.-H.; Lo, M.-Y.; Hung, S.-Y.; Chou, W.-C.; Tien, H.-F.; Hou, H.-A.; Chen, C.-Y.
10.1101/2023.11.13.563550 — bioinformatics — Posted on 2023-11-13
2797 Comprehensive profiling of L1 retrotransposons in mouse
Zhang, X.; Celic, I.; Mitchell, H.; Stuckert, S.; Vedula, L.; Han, J.
10.1101/2023.11.13.566638 — genomics — Posted on 2023-11-13
2799 The greening-causing agent alters the behavioral and electrophysiological responses of the Asian citrus psyllid to a putative sex pheromone
Volpe, H. X. L.; Carmo-Sousa, M.; Luvizotto, R. A. G.; de Freitas, R.; Esperanca, V.; Darolt, J. C.; Pegoraro, A. A. L.; Magalhaes, D. M.; Favaris, A. P.; Wulff, N. A.; Miranda, M. P.; Bento, J. M. S.; Leal, W. S.
10.1101/2023.11.09.566442 — zoology — Posted on 2023-11-13
2801 AAV-mediated gene therapy for Sialidosis
van de Vlekkert, D.; Hu, H.; Fremuth, L. E.; Brown, S. A.; Weesner, J. A.; Gomero, E.; Campos, Y.; d'Azzo, A.
10.1101/2023.11.10.566667 — genetics — Posted on 2023-11-13
2803 An Arabidopsis leaf expression atlas across diurnal and developmental scales
Vong, G.; McCarthy, K.; Claydon, W.; Davis, S. J.; Redmond, E. J.; Ezer, D.
10.1101/2023.11.10.566572 — plant biology — Posted on 2023-11-13
2809 De novo basecalling of m6A modifications at single molecule and single nucleotide resolution
Cruciani, S.; Delgado Tejedor, A.; Pryszcz, L.; Medina, R.; Llovera, L.; Novoa, E. M.
10.1101/2023.11.13.566801 — molecular biology — Posted on 2023-11-13
2810 SUMO protease and proteasome recruitment at the nuclear periphery differently affect replication dynamics at arrested forks.
Schirmeisen, K.; Naiman, K.; Freon, K.; Besse, L.; Chakraborty, S.; Carr, A.; Kramarz, K.; Lambert, S. A.
10.1101/2023.11.13.566856 — molecular biology — Posted on 2023-11-13
2811 The AccelerAge framework: A new statistical approach to predict biological age based on time-to-event data
Sluiskes, M. H.; Goeman, J. J.; Beekman, M.; Slagboom, P. E.; van den Akker, E. B.; Putter, H.; Rodriguez-Girondo, M.
10.1101/2023.11.13.566803 — molecular biology — Posted on 2023-11-13
2813 Understanding the bacterial imbalance in Hidradenitis Suppurativa patients: Insights into microbial community shifts and colonization by opportunistic pathogens
Bens, L.; Vanhoutvin, T.; Kerremans, A.; Jansen, D.; Depypere, M.; Hillary, T.; Vermeire, S.; Green, S. I.; Matthijnssens, J.; Sabino, J.; Lavigne, R.; Van Laethem, A.; Wagemans, J.
10.1101/2023.11.12.566737 — microbiology — Posted on 2023-11-13
2814 Oyster aquaculture enhances sediment microbial diversity- Insights from a multi-omics study
Stevens, J. T. E.; Ray, N. E.; Al-Haj, A. N.; Fulweiler, R. W.; Roy Chowdhury, P.
10.1101/2023.11.13.566866 — microbiology — Posted on 2023-11-13
2817 Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers and engulfment by microglia
Francis, V.; Liddle, C.; Camacho, E.; Kulkarni, M.; Junior, S. R.; Harvey, J. A.; Ballou, E. R.; Thompson, D. D.; Hardwick, J. M.; Casadevall, A.; Witton, J.; Coelho, C.
10.1101/2023.11.13.564824 — microbiology — Posted on 2023-11-13
2818 Exploring viral particle, soil, and extraction buffer physicochemical characteristics and their impacts on extractable viral communities
Fudyma, J. D.; ter Horst, A. M.; Santos-Medellin, C.; Sorensen, J.; Gogul, G.; Hillary, L.; Geonczy, S.; Pett-Ridge, J.; Emerson, J. B.
10.1101/2023.11.13.566929 — microbiology — Posted on 2023-11-13
2819 Infection pressure in apes has driven selection for CD4 alleles that resist lentivirus (HIV/SIV) infection
Warren, C.; Barbachano-Guerrero, A.; DuMont, V.; Stabell, A.; Dirasantha, O.; Yang, Q.; Sawyer, S. L.
10.1101/2023.11.13.566830 — microbiology — Posted on 2023-11-13
2820 Host kinase regulation of Plasmodium vivax dormant and replicating liver stages
Glennon, E. K.; Wei, L.; Roobsoong, W.; Primavera, V. I.; Tongogara, T.; Yee, C. B.; Sattabongkot, J.; Kaushansky, A.
10.1101/2023.11.13.566868 — microbiology — Posted on 2023-11-13
2821 Intestinal cDC1s provide IL-12 dependent and independent functions required for CD4+ T cell mediated resistance to Cryptosporidium
Cohn, I. S.; Wallbank, B. A.; Haskins, B. E.; O'Dea, K. M.; Pardy, R. D.; Shaw, S.; Merolle, M. I.; Gullicksrud, J.; Christian, D. A.; Striepen, B.; Hunter, C. A.
10.1101/2023.11.11.566669 — immunology — Posted on 2023-11-13
2822 Optical segmentation-based compressed readout of neuronal voltage dynamics
Choi, M. M.; Kim, S.; Ko, G.; Kang, I.; Tian, H.; Fan, L. Z.; Li, Y.; Cohen, A. E.; Wu, J.; Dai, Q.
10.1101/2023.11.10.566599 — neuroscience — Posted on 2023-11-13
2823 The neurocomputational link between defensive cardiac states and approach-avoidance arbitration under threat
Klaassen, F. H.; de Voogd, L. D.; Hulsman, A. M.; O'Reilly, J. X.; Klumpers, F.; Figner, B.; Roelofs, K.
10.1101/2023.11.10.566569 — neuroscience — Posted on 2023-11-13
2824 Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells
Iascone, D. M.; Zhang, X.; Bafford, P.; Mesaros, C.; Sela, Y.; Hofbauer, S.; Zhang, S. L.; Cook, K.; Pivarshev, P.; Stanger, B.; Anderson, S. A.; Dang, C. V.; Sehgal, A.
10.1101/2023.11.08.566310 — cancer biology — Posted on 2023-11-13
2825 Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signalling and clinical traits
Krishna, A.; Meynert, A.; Kelder, M.; Ewing, A.; Sheraz, S.; Ferrer-Vacquer, A.; Grimes, G.; Becher, H.; Silk, R.; Semple, C. A.; Kendall, T.; Hadjontanakis, A.-K.; Bird, T.; Marsh, J. A.; Hohenstein, P.; Wood, A. J.; Ozdemir, D. D.
10.1101/2023.11.09.566307 — cancer biology — Posted on 2023-11-13
2828 Intrinsic epigenetic state of primary osteosarcoma drives metastasis
Singh, I.; Rainusso, N.; Kurenbekova, L.; Nirala, B.; Dou, J.; Muruganandham, A.; Yustein, J. T.
10.1101/2023.11.09.566446 — cancer biology — Posted on 2023-11-13
2830 Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signalling and clinical traits
Krishna, A.; Meynert, A.; Kelder, M.; Ewing, A.; Sheraz, S.; Ferrer-Vacquer, A.; Grimes, G.; Becher, H.; Silk, R.; Semple, C. A.; Kendall, T.; Hadjantonakis, A.-K.; Bird, T.; Marsh, J. A.; Hohenstein, P.; Wood, A. J.; Ozdemir, D. D.
10.1101/2023.11.09.566307 — cancer biology — Posted on 2023-11-13
2832 eIF4A1 is essential for reprogramming the translational landscape of Wnt-driven colorectal cancers
Waldron, J. A.; Kanellos, G.; Smith, R. C. L.; Knight, J. R. P.; Munro, J.; Alexandrou, C.; Vlahov, N.; Pardo-Fernandez, L.; Moore, M.; Gillen, S. L.; Strathdee, D.; Stevenson, D.; Warrander, F. C.; Gilroy, K.; Nixon, C.; Cadden, B.; Powley, I.; Officer-Jones, L.; Ballantyne, F.; Hay, J.; Pennel, K.; Edwards, J.; Campbell, A. D.; Ridgway, R. A.; Coffelt, S. B.; Norman, J.; Le Quesne, J.; Bushell, M.; Sansom, O. J.
10.1101/2023.11.10.566546 — cancer biology — Posted on 2023-11-13
2833 Oncogenic RAS drives rapid onset cellular plasticity and elicits a tumour-promoting neutrophil response at the inception of preneoplastic development
Elliot, A. M.; Ribeiro Bravo, I.; Astorga Johansson, J.; Hutton, E.; Cunningham, R.; Myllymaki, H.; Chang, K. Y.; Beltran, M.; Dobie, R.; Elks, P.; Hansen, C. G. / G.; Henderson, N.; Feng, Y.
10.1101/2023.11.10.566547 — cancer biology — Posted on 2023-11-13
2835 Single protein molecules separation, tracking and counting in ultra-thin silicon channels
Ohayon, S.; Taib, L.; Verma, N. C.; Iarossi, M.; Bhattacharya, I.; Marom, B.; Huttner, D.; Meller, A.
10.1101/2023.11.09.566381 — biophysics — Posted on 2023-11-13
2837 Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment
Daugird, T. A.; Shi, Y.; Holland, K. L.; Rostamian, H.; Liu, Z.; Lavis, L. D.; Rodriguez, J.; Strahl, B. D.; Legant, W. R.
10.1101/2023.11.09.566470 — biophysics — Posted on 2023-11-13
2838 The pathogenic p.N1662D SCN2A mutation reveals an essential molecular interaction for Nav1.2 channel inactivation
Berecki, G.; Tao, E.; Howell, K. B.; Coorg, R. K.; Kahlig, K.; Wolff, M.; Corry, B.; Petrou, S.
10.1101/2023.11.12.566785 — biophysics — Posted on 2023-11-13
2843 Computational Identification of Potential Inhibitors Targeting cdk1 in Colorectal Cancer
Ogbodo, U. C.; Enejoh, O. A.; Okonkwo, C. H.; Gnanasekar, P.; Gachanja, P. W.; Osata, S.; Atanda, H. C.; Iwuchukwu, E. A.; Achilonu, I.; Awe, O. I.
10.1101/2023.11.09.566358 — bioinformatics — Posted on 2023-11-13
2844 ProkBERT Family: Genomic Language Models for Microbiome Applications
Ligeti, B.; Szepesi-Nagy, I.; Bodnar, B.; Ligeti-Nagy, N.; Juhasz, J.
10.1101/2023.11.09.566411 — bioinformatics — Posted on 2023-11-13
2845 Combinatorial in silico approach for cancer-associated 4Fe-4S protein discovery
Tam, W. W. L.; Cheng, M. H. W.; Mo, X.; He, B.-B.; Ngo, U. F. M.; Yuen, N. M. H.; Yau, A. Y. L.; Wu, N. C.; Tse, E. C. M.
10.1101/2023.11.08.566327 — bioinformatics — Posted on 2023-11-13
2848 GENTANGLE: integrated computational design of gene entanglements
Marti, J. M.; Hsu, C.; Rochereau, C.; Blazejewski, T.; Nisonoff, H.; Leonard, S. P.; Kang-Yun, C. S.; Chlebek, J. L.; Ricci, D. P.; Park, D. M.; Wang, H. H.; Listgarten, J.; Jiao, Y.; Allen, J. E.
10.1101/2023.11.09.565696 — bioinformatics — Posted on 2023-11-13
2853 MEM-GAN: A Pseudo Membrane Generator for Single-cell Imaging in Fluorescent Microscopy
Wang, Y.; Ding, J.; Wu, L.; Wardhani, A.; Danaher, P.; Lu, Q.; Wen, H.; Tang, W.; Chang, Y.; Lei, Y. L.; Tang, J.; Xie, Y.
10.1101/2023.11.08.566343 — bioinformatics — Posted on 2023-11-13
2858 Design of parallel ????-sheet nanofibrils using Monte-Carlo search, coarse-grained simulations, and experimental testing
Sarma, S.; Sudarshan, T. R.; Nguyen, V.; Robang, A. S.; Xiao, X.; Le, J. V.; Helmicki, M. E.; Paravastu, A. K.; Hall, C. K.
10.1101/2023.11.09.565678 — bioengineering — Posted on 2023-11-13
2859 Proximity Labeling Expansion Microscopy (PL-ExM) resolves structure of the interactome
Park, S.; Wang, X.; Li, X.; Huang, X.; Fong, K. C.; Yu, C.; Tran, A. A.; Scipioni, L.; Dai, Z.; Huang, L.; Shi, X.
10.1101/2023.11.09.566477 — bioengineering — Posted on 2023-11-13
2862 COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells
Pelosi, L.; Morbiato, L.; Burgardt, A.; Tonello, F.; Bartlett, A. K.; Guerra, R. M.; Ferizhendi, K. K.; Desbats, M. A.; Rascalou, B.; Marchi, M.; Vazquez-Fonseca, L.; Agosto, C.; Zanotti, G.; Roger-Margueritat, M.; Alcazar-Fabra, M.; Garcia-Corzo, L.; Sanchez-Cuesta, A.; Navas, P.; Brea-Calvo, G.; Trevisson, E.; Wendisch, V. F.; Pagliarini, D. J.; Salviati, L.; Pierrel, F.
10.1101/2023.11.13.566839 — biochemistry — Posted on 2023-11-13
2863 Structural basis for the concerted antiphage activity in the SIR2-HerA system
Yu, G.; liao, f.; zhang, c.; li, x.; he, q.; Yin, H.; li, z.; zhang, h.
10.1101/2023.11.13.566805 — biochemistry — Posted on 2023-11-13
2864 Nonribosomal peptide synthetases require dynamic interaction between modular domains
Zhang, C.-C.; Peng, Y.-J.; Zeng, X.; Chen, Y.; Zhou, C.-Z.; Miao, W.; Jiang, Y.-L.
10.1101/2023.11.13.566838 — biochemistry — Posted on 2023-11-13
2866 Cis- and trans-eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortia
Head, S. T.; Dezem, F.; Todor, A. T.; Yang, J.; Plummer, J. T.; Gayther, S.; Kar, S.; Schildkraut, J.; Epstein, M.
10.1101/2023.11.09.566218 — genetics — Posted on 2023-11-13
2868 Efficient genome editing using modified Cas9 proteins in zebrafish
Dorner, L.; Stratmann, B.; Bader, L.; Podobnik, M.; Irion, U.
10.1101/2023.11.12.566744 — genetics — Posted on 2023-11-13
2869 Xanthomonas rydalmerenesis sp. nov., a novel plant bacteria isolated from Fragaria x ananassa
McKnight, D. J. E.; Wong-Bajracharya, J.; Okoh, E. B.; Snijders, F.; Lidbetter, F.; Webster, J.; Haughton, M.; Darling, A. E.; Djordjevic, S. P.; Bogema, D. R.; Chapman, T. A.
10.1101/2023.11.12.566340 — genetics — Posted on 2023-11-13
2873 N-terminal toxin signal peptides efficiently load therapeutics into a natural nano-injection system
Steiner-Rebrova, E. M.; Ejaz, R. N.; Kielkopf, C. S.; Perez Ruiz, M.; Marin-Arraiza, L.; Hendriks, I. A.; Nissen, J. N.; Pozdnyakova, I.; Pape, T.; Regaiolo, A.; Goetz, K.; Heermann, R.; Rasmussen, S.; Nielsen, M. L.; Taylor, N. M. I.
10.1101/2023.11.13.566157 — molecular biology — Posted on 2023-11-13
2877 A Method for Analyzing AFM Force Mapping Data Obtained from Soft Tissue Cryosections
Wong, C. A.; Fraticelli Guzman, N. S.; Read, A. T.; Hedberg-Buenz, A.; Anderson, M. G.; Feola, A. J.; Sulchek, T.; Ethier, C. R.
10.1101/2023.11.08.566263 — bioengineering — Posted on 2023-11-13
2878 HIV viral protein R induces loss of DCT1-type renal tubules
Latt, K. Z.; Yoshida, T.; Shrivastav, S.; Abedini, A.; Reece, J. M.; Sun, Z.; Lee, H.; Okamoto, K.; Dagur, P.; Heymann, J.; Zhao, Y.; Chung, J.-Y.; Hewitt, S.; Jose, P. A.; Lee, K.; He, J.; Winkler, C. A.; Knepper, M. A.; Kino, T.; Rosenberg, A. Z.; Susztak, K.; Kopp, J. B.
10.1101/2023.02.02.526686 — pathology — Posted on 2023-11-13
2881 PCDH15 Dual-AAV Gene Therapy for Deafness and Blindness in Usher Syndrome Type 1F
Ivanchenko, M. V.; Hathaway, D. M.; Mulhall, E. M.; Booth, K. T.; Wang, M.; Peters, C. W.; Klein, A. J.; Chen, X.; Li, Y.; György, B.; Corey, D. P.
10.1101/2023.11.09.566447 — neuroscience — Posted on 2023-11-13
2882 Extending Subcortical EEG Responses to Continuous Speech to the Sound-Field
Bachmann, F. L.; Kulasingham, J. P.; Eskelund, K.; Enqvist, M.; Alickovic, E.; Innes-Brown, H.
10.1101/2023.11.08.566173 — neuroscience — Posted on 2023-11-13
2883 Disrupted sleep-wake regulation in the MCI-Park mouse model of Parkinson's Disease
Summa, K. C.; Jiang, P.; Gonzalez-Rodriguez, P.; Huang, X.; Lin, X.; Vitaterna, M. H.; Dan, Y.; Surmeier, D. J.; Turek, F. W.
10.1101/2023.11.09.566376 — neuroscience — Posted on 2023-11-13
2886 KSR1 Knockout Mouse Model Demonstrates MAPK Pathway's Key Role in Cisplatin- and Noise-induced Hearing Loss
Ingersoll, M. A.; Lutze, R. D.; Kelmann, R. G.; Kresock, D. F.; Marsh, J. D.; Quevedo, R. V.; Zuo, J.; Teitz, T.
10.1101/2023.11.08.566316 — neuroscience — Posted on 2023-11-13
2888 Spatiotemporal EP4-fibulin-1 expression is associated with vascular intimal hyperplasia
Okumura, S.; Yokoyama, U.; Oka, S.; Sasaki, T.; Cooley, M. A.; Hidaka, Y.; Tanifuji, S.; Kaneko, M.; Abe, T.; Breyer, R. M.; Homma, H.; Kato, Y.
10.1101/2023.11.09.566500 — physiology — Posted on 2023-11-13
2891 Fitness landscape of substrate-adaptive mutations in evolved APC transporters
Karapanagioti, F.; Atlason, U. A.; Slotboom, D. J.; Poolman, B.; Obermaier, S.
10.1101/2023.10.12.562049 — biochemistry — Posted on 2023-11-13
2895 Nuclear dualism without extensive DNA elimination in the ciliate Loxodes magnus
Seah, B. K. B.; Singh, A.; Vetter, D. E.; Emmerich, C.; Peters, M.; Soltys, V.; Huettel, B.; Swart, E.
10.1101/2023.11.09.566212 — genomics — Posted on 2023-11-13
2896 An encyclopedia of enhancer-gene regulatory interactions in the human genome
Gschwind, A. R.; Mualim, K. S.; Karbalayghareh, A.; Sheth, M. U.; Dey, K. K.; Jagoda, E.; Nurtdinov, R. N.; Xi, W.; Tan, A. S.; Jones, H.; Ma, X. R.; Yao, D.; Nasser, J.; Avsec, Z.; James, B. T.; Shamim, M. S.; Durand, N. C.; Rao, S. S. P.; Mahajan, R.; Doughty, B. R.; Andreeva, K.; Ulirsch, J. C.; Fan, K.; Perez, E. M.; Nguyen, T. C.; Kelley, D. R.; Finucane, H. K.; Moore, J. E.; Weng, Z.; Kellis, M.; Bassik, M. C.; Price, A. L.; Beer, M. A.; Guigo, R.; Stamatoyannopoulos, J. A.; Aiden, E. L.; Greenleaf, W. J.; Leslie, C. S.; Steinmetz, L. M.; Kundaje, A.; Engreitz, J. M.
10.1101/2023.11.09.563812 — genomics — Posted on 2023-11-13
2898 Genome folding principles revealed in condensin-depleted mitotic chromosomes
Zhao, H.; Lin, Y.; Lin, E.; Liu, F.; Shu, L.; Jing, D.; Wang, B.; Wang, M.; Shan, F.; Zhang, L.; Lam, J.; Midla, S.; Giardine, B.; Keller, C.; Hardison, R.; Blobel, G.; Zhang, H.
10.1101/2023.11.09.566494 — genomics — Posted on 2023-11-13
2901 Abundance of mega-carcasses does not profoundly affect trends in the population dynamics of a facultative scavenger predator and its prey
Sidous, M.; Cubaynes, S.; Gimenez, O.; Drouet-Hoguet, N.; Dray, S.; Bollache, L.; Madhlamoto, D.; Ngwenya, N. A.; Fritz, H.; Valeix, M.
10.1101/2023.11.08.566247 — ecology — Posted on 2023-11-13
2902 Metapopulations, the inflationary effect, and consequences for public health
Kortessis, N.; Glass, G.; Gonzalez, A.; Ruktanonchai, N. W.; Simon, M. W.; Singer, B.; Holt, R. D.
10.1101/2023.10.30.564450 — ecology — Posted on 2023-11-13
2904 Climate Change Factors Interactively Shift Peatland Functional Microbial Composition in a Whole-Ecosystem Warming Experiment
Kilner, C. L.; Carrell, A. A.; Wieczynski, D. J.; Votzke, S.; DeWitt, K.; Yammine, A.; Shaw, J.; Pelletier, D. A.; Weston, D. J.; Gibert, J. P.
10.1101/2023.03.06.531192 — ecology — Posted on 2023-11-13
2907 The mitochondrial deoxyguanosine kinase is required for female fertility in mice
Gao, Y.; Dong, R.; Yan, J.; Chen, H.; Sang, L.; Yao, X.; Fan, D.; Wang, X.; Zuo, X.; Zhang, X.; Yang, S.; Wu, Z.; sun, j.
10.1101/2023.11.12.566728 — cell biology — Posted on 2023-11-13
2908 Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway
Liu, X.; Yam, P.; Schlienger, S.; Cai, E.; Zhang, J.; Chen, W.-J.; Torres Gutierrez, O.; Jimenez Amilburu, V.; Ramamurthy, V.; Ting, A. Y.; Branon, T. C.; Cayouette, M.; Gen, R.; Marks, T.; Kong, J.; Charron, F.; Ge, X.
10.1101/2022.10.10.511655 — cell biology — Posted on 2023-11-13
2909 Post-transcriptional splicing can occur in a slow-moving zone around the gene
Cote, A. J.; O'Farrell, A.; Dardani, I.; Dunagin, M.; Cote, C. J.; Wan, Y.; Bayatpour, S.; Drexler, H. L.; Alexander, K. A.; Chen, F.; Wassie, A. T.; Patel, R.; Pham, K.; Boyden, E. S.; Berger, S.; Phillips-Cremins, J.; Churchman, L. S.; Raj, A.
10.1101/2020.04.06.028092 — cell biology — Posted on 2023-11-13
2910 The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model
Ruelas Castillo, J.; Neupane, P.; Karanika, S.; Krug, S.; Quijada, D.; Garcia, A.; Ayeh, S.; Yilma, A.; Costa, D. L.; Sher, A.; Fotouhi, N.; Serbina, N.; Karakousis, P. C.
10.1101/2023.08.09.552716 — microbiology — Posted on 2023-11-13
2912 A modular platform to display multiple hemagglutinin subtypes on a single immunogen
Lamson, D. T.; Mohamed, F. A. N.; Vu, M.; Maurer, D. P.; Ronsard, L.; Lingwood, D.; Schmidt, A. G.
10.1101/2023.11.09.566478 — immunology — Posted on 2023-11-13
2913 Single cell spatial transcriptomic profiling of childhood-onset lupus nephritis reveals complex interactions between kidney stroma and infiltrating immune cells.
Danaher, P.; Hasle, N.; Nguyen, E.; Hayward, K.; Rosenwasser, N.; Alpers, C. E.; Reed, R. C.; Okamura, D.; Baxter, S. K.; Jackson, S. W.
10.1101/2023.11.09.566503 — immunology — Posted on 2023-11-13
2914 Fast and tight control of motor vigor by accumulated decision evidence
Molano-Mazon, M.; Garcia-Duran, A.; Pastor-Ciurana, J.; Hernandez-Navarro, L.; Bektic, L.; Lombardo, D.; de la Rocha, J.; Hyafil, A.
10.1101/2023.11.09.566389 — neuroscience — Posted on 2023-11-13
2915 Microglial NF-κB Signaling Deficiency Protects Against Metabolic Disruptions Caused by Volatile Organic Compound via Modulating the Hypothalamic Transcriptome
Debarba, L. K.; Jayarathne, H. S. M.; Stilgenbauer, L.; Terra dos Santos, A. L. R.; Koshko, L.; Scofield, S.; Sullivan, R.; Mandal, A.; Klueh, U.; Sadagurski, M.
10.1101/2023.11.08.566279 — neuroscience — Posted on 2023-11-13
2917 Chronic pain mediated changes in the appetitive value of affective touch in mice
Zain, M.; Bennett, L. A.; Zhang, H.; Pauli, Q.; Arsenault, J.; Premachandran, S.; Cheung, J.; Pham, C.; Wowk, L.; Kaba, S. O.; Fung, S.; Lecker, I.; Salter, E. W.; Wang, F.; Sharif-Naeini, R.; De Koninck, Y.; Bonin, R. P.
10.1101/2023.11.09.566431 — neuroscience — Posted on 2023-11-13
2918 General anaesthesia reduces the uniqueness of brain connectivity across individuals and across species
Luppi, A. I.; Golkowski, D.; Ranft, A.; Ilg, R.; Jordan, D.; Bzdok, D.; Owen, A. M. I.; Naci, L.; Stamatakis, E. A.; Amico, E. A.; Misic, B.
10.1101/2023.11.08.566332 — neuroscience — Posted on 2023-11-13
2919 Characterising the contribution of auditory and somatosensory inputs to TMS-evoked potentials following stimulation of prefrontal, premotor and parietal cortex
Biabani, M.; Fornito, A.; Goldsworthy, M.; Thompson, S.; Graetz, L.; Semmler, J. G.; Opie, G. M.; Bellgrove, M. A.; Rogasch, N. C.
10.1101/2023.11.09.566371 — neuroscience — Posted on 2023-11-13
2921 Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants
Prigge, M. J.; Morffy, N.; De Neve, A.; Szutu, W.; Juarez, M. J. A.; Johnson, K.; Do, N.; Lavy, M.; Hake, S.; Strader, L.; Estelle, M.; Richardson, A. E.
10.1101/2023.11.09.566459 — plant biology — Posted on 2023-11-13
2922 Systems analysis of long-term heat stress responses in the C4 grass Setaria viridis
Zhang, P.; Sharwood, R. E.; Carroll, A. J.; von Caemmerer, S.; Furbank, R. T.
10.1101/2023.11.09.566437 — plant biology — Posted on 2023-11-13
2923 CLAIR: An integrated lipid database across multiple crop species
He, B.; Bu, M.; Lin, Q.; Fu, Z.; Xie, J.; Fan, W.; Li, J.; Li, R.; Hua, W.; Liu, W.; Cui, P.
10.1101/2023.11.08.566134 — plant biology — Posted on 2023-11-13
2925 UDP-glucosyltransferase 71C4 regulates seed development by redistributing phenylpropanoid metabolism in cotton
Cao, Y.; Han, Z.; He, L.; Huang, C.; Chen, J.; Dai, F.; Xuan, L.; Yan, S.; Si, Z.; Hu, Y.; Zhang, T.
10.1101/2023.11.09.566436 — plant biology — Posted on 2023-11-13
2926 Titin-based force regulates cardiac myofilament structures mediating length-dependent activation
Hessel, A. L.; Kuehn, M. N.; Engels, N. M.; Nissen, D. L.; Freundt, J. K.; Ma, W.; Irving, T. C.; Linke, W. A.
10.1101/2023.11.09.566413 — physiology — Posted on 2023-11-13
2927 High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia
Herup-Wheeler, T.; Shi, M.; Harvey, M. E.; Talwar, C.; Kommagani, R.; MacLean, J. A.; Hayashi, K.
10.1101/2023.11.09.566474 — physiology — Posted on 2023-11-13
2928 The Cardiac Calcium Handling Machinery is Remodeled in Friedreich's Ataxia
Czornobil, R.; Assali, O. A.-; Wood, E. R.-; Lynch, D. R.; Noujaim, S. F.; Chidipi, B.
10.1101/2023.11.09.566141 — physiology — Posted on 2023-11-13
2929 In vivo and in silico experiment on Mitragyna speciosa offers new insight of antidiabetic potentials
Hossain, M. U.; Hossain, M. S.; Dey, S.; Chowdhury, Z. M.; Rahman, A. B. Z. N.; Bhattacharjee, A.; Ahammad, I.; Islam, M. N.; Moniruzzaman, M.; Hosen, M. B.; Ahmed, I.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.11.08.566341 — pharmacology and toxicology — Posted on 2023-11-13
2937 Multi-modal breath measurements for biomarker discovery
Tomezsko, P.; Wynn, J.; Ostrinskaya, A.; Hendricks, J.; Vian, T.
10.1101/2023.11.09.566302 — genomics — Posted on 2023-11-13
2940 Reconciling land sharing and sparing: a conceptual model for land use
Fioratti, M.; Borchers, N.; Reid, B. J.; Sims, I.; Miller, A. J.
10.1101/2023.11.09.566356 — ecology — Posted on 2023-11-13
2942 Metabolic Reprogramming of the Neovascular Niche Promotes Regenerative Angiogenesis in Proliferative Retinopathy
Cagnone, G.; Pundir, S.; Sung-Kim, J.; Rivera, J. C.; Agnihotri, T.; Harvey, N.-R.; Heckel, E.; Betus, C.; Chen, M. X.; Situ, A.; Gaub, P.; Kim, N.; Das, A.; Leclerc, S.; Wunnemann, F.; Andelfinger, G.; Crespo-Garcia, S.; Dubrac, A.; Rezende, F.; Clish, C. B.; Maranda, B.; Smith, L. E. H.; Sapieha, P.; Joyal, J.-S.
10.1101/2023.11.13.566898 — cell biology — Posted on 2023-11-13
2943 Coordination of focal adhesion nanostructure and mechano-signaling drives cardiomyocyte differentiation
Xiao, J.; Zhong, X.; Ang, J. W.; Wong, D. C. P.; Lee, C. J. M.; Foo, R. S.-Y.; Kanchanawong, P.; Low, B. C.
10.1101/2023.11.13.566796 — cell biology — Posted on 2023-11-13
2946 Endonucleosis mediates internalization of cytoplasm into the nucleus in senescent cells
Galanopoulou, O.; Tachmatzidi, E. C.; Deligianni, E.; Botskaris, D.; Nikolaou, K. C.; Garganis, S.; Dalezios, Y.; Chalepakis, G.; Talianidis, I.
10.1101/2023.11.12.566736 — cell biology — Posted on 2023-11-13
2947 Dynamic Regulation of Innate Lymphoid Cell Development During Ontogeny
Wu, T.; Chen, S.; Ma, J.; Zhu, X.; Luo, M.; Wang, Y.; Tian, Y.; Sun, Q.; Guo, X.; Zhang, J.; Zhang, X.; Zhu, Y.; Wu, L.
10.1101/2023.11.01.565141 — immunology — Posted on 2023-11-13
2948 scDrugPrio: A framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases
Schaefer, S.; Smelik, M.; Sysoev, O.; Zhao, Y.; Eklund, D.; Lilja, S.; Gustafsson, M.; Heyn, H.; Julia, A.; Kovacs, I. A.; Loscalzo, J.; Marsal, S.; Zhang, H.; Li, X.; Gawel, D.; Wang, H.; Benson, M.
10.1101/2023.11.08.566249 — immunology — Posted on 2023-11-13
2950 Host PGD2 acting on DP2 receptor attenuates Schistosoma mansoni infection-driven hepatic granulomatous fibrosis
Pezzella-Ferreira, G. N.; Pao, C. R. R.; Bellas, I.; Luna-Gomes, T.; Muniz, V. S.; Paiva, L. A.; Amorim, N. R. T.; Canetti, C.; Bozza, P. T.; Diaz, B. L.; Bandeira-Melo, C.
10.1101/2023.11.09.566508 — immunology — Posted on 2023-11-13
2951 Socioeconomic resources in youth are linked to divergent patterns of network integration and segregation across the brain's transmodal axis
Michael, C.; Taxali, A.; Angstadt, M.; Kardan, O.; Weigard, A.; Molloy, F.; McCurry, K. L.; Hyde, L. W.; Heitzeg, M. M.; Sripada, C.
10.1101/2023.11.08.565517 — neuroscience — Posted on 2023-11-13
2952 Rit2 loss in dopaminergic neurons drives a Parkinsonian phenotype
Kearney, P. J.; Zhang, Y.; Tan, Y.; Kahuno, E.; Conklin, T.; Fagan, R. R.; Pavchinskiy, R. G.; Shaffer, S. A.; Yue, Z.; Melikian, H. E.
10.1101/2023.04.26.538430 — neuroscience — Posted on 2023-11-13
2953 Investigating egocentric tuning in hippocampal CA1 neurons using simulated data
Carpenter, J.; Blackstad, J. S.; Tingley, D.; Normand, V. A.; Moser, E. I.; Moser, M.-B.; Dunn, B. A.
10.1101/2023.11.08.566253 — neuroscience — Posted on 2023-11-13
2954 Stacking models of brain dynamics improves prediction of subject traits in fMRI
Griffin, B.; Ahrends, C.; Alfaro-Almagro, F.; Woolrich, M.; Smith, S.; Vidaurre, D.
10.1101/2023.11.08.566196 — neuroscience — Posted on 2023-11-13
2955 Tuning the brakes: Modulatory role of transcranial random noise stimulation on inhibition
Mandali, A.; Torrecillos, F.; Wiest, C.; Pogosyan, A.; He, S.; Soriano, D. C.; Tan, H.; Stagg, C. J.; Cagnan, H.
10.1101/2023.11.09.565862 — neuroscience — Posted on 2023-11-13
2958 Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes
Farrell, K.; Humphrey, J.; Chang, T.; Zhao, Y.; Leung, Y. Y.; Kuksa, P. P.; Patil, V.; Lee, W.-P.; Kuzma, A. B.; Valladares, O.; Cantwell, L. B.; Wang, H.; Ravi, A.; De Sanctis, C.; Han, N.; Christie, T. D.; Whitney, K.; Krassner, M. M.; Walsh, H.; Kim, S.; Dangoor, D.; Iida, M. A.; Casella, A.; Walker, R. H.; Nirenberg, M. J.; Renton, A. E.; Babrowicz, B.; Coppola, G.; Raj, T.; Hoglinger, G. U.; Golbe, L. I.; Morris, H. R.; Hardy, J.; Revesz, T.; Warner, T. T.; Jaunmuktane, Z.; Mok, K. Y.; Rademakers, R.; Dickson, D. W.; Ross, O. A.; Wang, L.-S.; Goate, A.; Schellenberg, G.; Geschwind, D. H.;
10.1101/2023.11.09.565552 — neuroscience — Posted on 2023-11-13
2959 Three-dimensional electro-neural interfaces electroplated on subretinal prostheses
Butt, E.; Wang, B.-Y.; Shin, A.; Chen, Z. C.; Bhuckory, M. B.; Shah, S.; Galambos, L.; Kamins, T.; Palanker, D.; Mathieson, K.
10.1101/2023.11.09.566003 — neuroscience — Posted on 2023-11-13
2960 Microbiota-dependent early life programming of gastrointestinal motility
Frith, M. E.; Kashyap, P. C.; Linden, D. R.; Theriault, B.; Chang, E. B.
10.1101/2023.11.08.566304 — physiology — Posted on 2023-11-13
2962 Behavioral adaptation to changing energy constraints via altered frequency of movement selection
Darveniza, T.; Zhu, S. I.; Pujic, Z.; Sun, B.; Levendosky, M.; Wong, R.; Agarwal, R.; McCullough, M. H.; Goodhill, G. J.
10.1101/2023.11.08.566262 — animal behavior and cognition — Posted on 2023-11-13
2963 Multidimensional behavioral profiles associated with resilience and susceptibility after inescapable stress
de Oliveira-Junior, B. A.; Marques, D. B.; Rossignoli, M. T.; Prizon, T.; Leite, J. P.; Ruggiero, R. N.
10.1101/2023.11.08.566266 — animal behavior and cognition — Posted on 2023-11-13
2967 Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips
Izadifar, Z.; Cotton, J.; Chen, C.; Bustos, N. A.; Horvath, V.; Stejskalova, A.; Wu, C.; Gulati, A.; LoGrande, N. T.; Budnik, B.; Shahriar, S.; Doherty, E.; To, T.; Gilpin, S. E.; Sesay, A. M.; Goyal, G.; Ribbeck, K.; Lebrilla, C. B.; Ingber, D. E.
10.1101/2023.02.22.529436 — bioengineering — Posted on 2023-11-13
2968 Noncanonical usage of stop codons in ciliates expands proteins with Q-rich motifs
Chuang, C.-N.; Liu, H.-C.; Woo, T.-T.; Hu, H.-T.; Chao, J.-L.; Chen, C.-Y.; Hsueh, Y.-P.; Wang, T.-F.
10.1101/2020.12.08.407247 — biochemistry — Posted on 2023-11-13
2971 Holistic in silico developability assessment of novel classes of small proteins using publicly available sequence-based predictors
Pais, D. A. M.; Mayer, J.-P. A.; Felderer, K.; Batalha, M. B.; Eichner, T.; Santos, S. T.; Kumar, R.; Silva, S. D.; Kaufmann, H.
10.1101/2023.11.10.566515 — biochemistry — Posted on 2023-11-13
2972 Evolutionary analysis reveals the role of a non-catalytic domain of peptidyl arginine deiminase 2 in transcriptional regulation
Villanueva-Canas, J. L.; Fernandez-Fuentes, N.; Saul, D.; Kosinsky, R. L.; Teyssier, C.; Rogalska, M. E.; Perez, F. P.; Oliva, B.; Notredame, C.; Beato, M.; Sharma, P.
10.1101/2022.09.19.508513 — evolutionary biology — Posted on 2023-11-13
2974 The Parkinson's drug entacapone disrupts gut microbiome homeostasis via iron sequestration
Pereira, F. C.; Ge, X.; Kristensen, J. M.; Kirkegaard, R. H.; Maritsch, K.; Zu, Y.; Decorte, M.; Hausmann, B.; Berry, D.; Wasmund, K.; Schintlmeister, A.; Boettcher, T.; Cheng, J.-X.; Wagner, M.
10.1101/2023.11.12.566429 — microbiology — Posted on 2023-11-13
2976 No evidence that post-training D2R dopaminergic drug administration affects fear generalization in male rats
Schroyens, N.; Vercammen, L.; Ozcan, B.; Ossorio Salazar, V. A.; Zaman, J.; De Bundel, D.; Beckers, T.; Luyten, L.
10.1101/2022.02.02.478781 — neuroscience — Posted on 2023-11-13
2977 Dopamine and neuromodulation accelerate the neural dynamics of volitional action in Parkinson's disease
Köhler, R. M.; Binns, T. S.; Merk, T.; Zhu, G.; Yin, Z.; Zhao, B.; Chikermane, M.; Vanhoecke, J.; Busch, J. L.; Habets, J. G. V.; Faust, K.; Schneider, G.-H.; Cavallo, A.; Haufe, S.; Zhang, J.; Kühn, A. A.; Haynes, J.-D.; Neumann, W.-J.
10.1101/2023.10.30.564700 — neuroscience — Posted on 2023-11-13
2978 Fibre-specific mitochondrial protein abundance is linked to resting and post-training mitochondrial content in human muscle.
Reisman, E.; Botella Ruiz, J.; Huang, C.; Schittenhelm, R. B.; Stroud, D. A.; Granata, C.; Chandrasiri, S.; Ramm, G.; Oorschot, V.; Caruana, N. J.; Bishop, D. J.
10.1101/2022.10.23.512956 — physiology — Posted on 2023-11-13
2979 Sequence-ensemble-function relationships for disordered proteins in live cells
Emenecker, R. J.; Guadalupe, K.; Shamoon, N. M.; Sukenik, S.; Holehouse, A. S.
10.1101/2023.10.29.564547 — biophysics — Posted on 2023-11-13
2981 FeS-thioredoxin regulates suppression of hypoxia-induced factor 2α through iron regulatory protein 1
Berndt, C.; Hanschmann, E.-M.; Jordt, L. M.; Gellert, M.; Thewes, L.; Ortegon Salas, C.; Poschmann, G.; Mueller, C. S.; Bodnar, Y.; Schippers, S.; Handorf, O.; Nowack, R.; Moulis, J.-M.; Schulzke, C.; Schuenemann, V.; Lillig, C. H.
10.1101/2020.08.04.235721 — biochemistry — Posted on 2023-11-13
2982 Heterotypic stressors unmask behavioral influences of PMAT deficiency in mice
Weber, B. L.; Nicodemus, M. M.; Hite, A. K.; Spalding, I. R.; Beaver, J. N.; Scrimshaw, L. R.; Kassis, S. K.; Reichert, J. M.; Ford, M. T.; Russell, C. N.; Hallal, E. M.; Gilman, T. L.
10.1101/2023.08.30.555632 — neuroscience — Posted on 2023-11-13
2983 Bacteriophage-host interactions in microgravity onboard the International Space Station
Huss, P.; Chitboonthavisuk, C.; Meger, A.; Nishikawa, K.; Oates, R. P.; Mills, H.; Holzhaus, O.; Raman, S.
10.1101/2023.10.10.561409 — synthetic biology — Posted on 2023-11-13
2986 Future movement plans interact in sequential arm movements
Kashefi, M.; Reschechtko, S.; Ariani, G.; Shahbazi, M.; Tan, A.; Diedrichsen, J.; Pruszynski, J. A.
10.1101/2023.05.24.542099 — neuroscience — Posted on 2023-11-13
2988 Hippocampal networks support reinforcement learning in partially observable environments
Pedamonti, D.; Mohinta, S.; Dimitrov, M.; Malagon-Vina, H.; Ciocchi, S.; Costa, R. P.
10.1101/2023.11.09.565503 — neuroscience — Posted on 2023-11-13
2989 osl-dynamics: A toolbox for modelling fast dynamic brain activity
Gohil, C.; Huang, R.; Roberts, E.; van Es, M. W. J.; Quinn, A. J.; Vidaurre, D.; Woolrich, M. W.
10.1101/2023.08.07.549346 — neuroscience — Posted on 2023-11-13
2991 In-vivo multicellular control of gene expression in microbial consortia
Salzano, D.; Shannon, B.; Grierson, C.; Marucci, L.; Savery, N.; di Bernardo, M.
10.1101/2023.11.13.566807 — synthetic biology — Posted on 2023-11-13
2992 Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors
Nigam, A.; Hurley, M. F. D.; Li, F.; Konkolova, E.; Klima, M.; Trylcova, J.; Pollice, R.; Cınaroglu, S. S.; Levin-Konigsberg, R.; Handjaya, J.; Schapira, M.; Chau, I.; Perveen, S.; Ng, H.-L.; Kaniskan, H. U.; Han, Y.; Singh, S.; Gorgulla, C.; Kundaje, A.; Jin, J.; Voelz, V. A.; Weber, J.; Nencka, R.; Boura, E.; Vedadi, M.; Aspuru-Guzik, A.
10.1101/2023.10.03.560722 — biochemistry — Posted on 2023-11-13
2995 Paternal genomic resources from the YanHuang cohort suggested a Weakly-Differentiated Multi-source Admixture model for the formation of Hans founding ancestral lineages
Wang, Z.; Wang, M.; Liu, K.; Yuan, H.; Duan, S.; Liu, Y.; Luo, L.; Jiang, X.; Chen, S.; Wei, L.; Tang, R.; Hu, L.; Chen, J.; Li, X.; Yang, Q.; Sun, Y.; Sun, Q.; Huang, Y.; Su, H.; Zhong, J.; Yao, H.; Yun, L.; Bo, J.; Yang, J.; Cai, Y.; Deng, H.; Yan, J.; Zhu, B.; 10K_CPGDP, ; Zhou, K.; Nie, S.; Liu, C.; He, G.
10.1101/2023.11.08.566335 — evolutionary biology — Posted on 2023-11-13
2996 Investigation of contributions from cortical and subcortical brain structures for speech decoding
Wu, H.; Cai, C.; Ming, W.; Chen, W.; Zhu, Z.; Feng, C.; Jiang, H.; Zheng, Z.; Sawan, M.; Wang, T.; Zhu, J.
10.1101/2023.11.12.566678 — neuroscience — Posted on 2023-11-13
2997 Pre-processing of paleogenomes: Mitigating reference bias and postmortem damage in ancient genome data
Koptekin, D.; Yapar, E.; Vural, K. B.; Saglıcan, E.; Altınısık, N. E.; Malaspinas, A.-S.; Alkan, C.; Somel, M.
10.1101/2023.11.11.566695 — bioinformatics — Posted on 2023-11-13
2998 Distinct developmental trajectories of autonomous behaviors and agency in rodents
Mitelut, C.; Diez Castro, M.; Peterson, R. E.; Goncalves, M.; Gamer, M. M.; Nilsson, S. R. O.; Pereira, T. D.; Sanes, D. H.
10.1101/2023.11.10.566632 — animal behavior and cognition — Posted on 2023-11-13
2999 Nucleus accumbens dopamine release reflects Bayesian inference during instrumental learning
Qu, A. J.; Tai, L.-H.; Hall, C. D.; Tu, E. M.; Eckstein, M. K.; Mischanchuk, K.; Lin, W. C.; Chase, J. B.; MacAskill, A. F.; Collins, A. G. E.; Gershman, S. J.; Wilbrecht, L.
10.1101/2023.11.10.566306 — animal behavior and cognition — Posted on 2023-11-13
3002 Molecular and Cellular Context Influences SCN8A Variant Function
Vanoye, C. G.; Abramova, T. V.; DeKeyser, J.-M.; Ghabra, N.; Oudin, M.; Burge, C.; Helbig, I.; Thompson, C. H.; George, A. L.
10.1101/2023.11.11.566702 — neuroscience — Posted on 2023-11-13
3003 Network Enrichment Significance Testing in Brain-Phenotype Association Studies
Weinstein, S. M.; Vandekar, S. N.; Alexander-Bloch, A. F.; Raznahan, A.; Li, M.; Gur, R. E.; Gur, R. C.; Roalf, D. R.; Park, M. T. M.; Chakravarty, M.; Baller, E. B.; Linn, K. A.; Satterthwaite, T. D.; Shinohara, R. T.
10.1101/2023.11.10.566593 — neuroscience — Posted on 2023-11-13
3005 Multivariate links between the developmental timing of adversity exposure and white matter tract integrity in adulthood
Sisk, L. M.; Keding, T. J.; Cohodes, E. M.; McCauley, S.; Pierre, J. C.; Odriozola, P.; Kribakaran, S.; Haberman, J. T.; Zacharek, S. J.; Hodges, H. R.; Caballero, C.; Gold, G.; Huang, A. Y.; Talton, A.; Gee, D. G.
10.1101/2023.11.12.566271 — neuroscience — Posted on 2023-11-13
3010 Ribosome Decision Graphs for the Representation of Eukaryotic RNA Translation Complexity
Tierney, J. A. T.; Swirski, M.; Tjeldnes, H.; Mudge, J. M.; Kufel, J.; Whiffin, N.; Valen, E.; Baranov, P.
10.1101/2023.11.10.566564 — genomics — Posted on 2023-11-12
3011 What does the fox (genome) say? A chromosome-level assembly for the gray fox (Urocyon cinereoargenteus)
Armstrong, E. E.; Bissell, K. L.; Heikkinen, M. A.; Jessup, A.; Junaid, M. O.; Lee, D. H.; Lieb, E. C.; Liem, J. T.; Martin, E. M.; Moreno, M.; Otgonbayar, K.; Romans, B. W.; Royar, K.; Adler, M. B.; Needle, D. B.; Harkess, A.; Kelley, J. L.; Mooney, J. A.; Mychajliw, A. M.
10.1101/2023.11.08.566296 — genomics — Posted on 2023-11-12
3012 Single Nucleus RNA Sequencing of Remnant Kidney Biopsies and Urine Cell RNA Sequencing Reveal Cell Specific Markers of Covid-19 Acute Kidney Injury
Ghag, R.; Kaushal, M.; Nwanne, G.; Knoten, A.; Kiryluk, K.; Rosenberg, A.; Menez, S.; Bagnasco, S. M.; Sperati, C. J.; Atta, M. G.; Gaut, J. P.; Williams, J. C.; El-Achkar, T. M.; Arend, L. J.; Parikh, C. R.; Jain, S.
10.1101/2023.11.10.566497 — genetics — Posted on 2023-11-12
3013 Benchmarking kinship estimation tools for ancient genomes using pedigree simulations
Aktürk, S.; Mapelli, I.; Güler, M. N.; Gürün, K.; Katırcıoglu, B.; Vural, K. B.; Saglıcan, E.; Cetin, M.; Yaka, R.; Sürer, E.; Atag, G.; Cokoglu, S. S.; Sevkar, A.; Altınısık, N. E.; Koptekin, D.; Somel, M.
10.1101/2023.11.08.566300 — genetics — Posted on 2023-11-12
3014 Genetic Discovery Enabled by A Large Language Model
Tu, T.; Fang, Z.; Cheng, Z.; Spasic, S.; Palepu, A.; Stankovic, K.; Natarajan, V.; Peltz, G.
10.1101/2023.11.09.566468 — genetics — Posted on 2023-11-12
3016 Amoebozoan testate amoebae illuminate the diversity of heterotrophs and the complexity of ecosystems throughout geological time
Porfirio-Sousa, A. L.; Tice, A. K.; Morais, L.; Ribeiro, G. M.; Blandenier, Q.; Dumack, K.; Eglit, Y.; Fry, N. W.; Gomes E Souza, M. B.; Henderson, T.; Kleitz-Singleton, F.; Singer, D.; Brown, M. W.; Lahr, D. J. G.
10.1101/2023.11.08.566222 — evolutionary biology — Posted on 2023-11-12
3018 Soil seed bank richness, abundance and density across spatial scales and global biomes
Auffret, A. G.; Ladouceur, E.; Haussmann, N. S.; Keil, P.; Daouti, E.; Elumeeva, T. G.; Kacergyte, I.; Knape, J.; Kotowska, D.; Low, M.; Onipchenko, V. G.; Paquet, M.; Rubene, D.; Plue, J.
10.1101/2023.11.08.566230 — ecology — Posted on 2023-11-12
3019 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'
Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.
10.1101/2023.11.08.566206 — ecology — Posted on 2023-11-12
3021 A synthetic CRISPR-Cas nuclease with expanded enzymatic activities
Jabalera, Y.; Tascon, I.; Samperio, S.; Lopez-Alonso, J. P.; Gonzalez-Lopez, M.; Aransay, A. M.; Abascal-Palacios, G.; Ubarretxena-Belandia, I.; Perez-Jimenez, R.
10.1101/2023.11.12.566739 — molecular biology — Posted on 2023-11-12
3022 The Parkinson's drug entacapone disrupts gut microbiome homeostasis via iron sequestration
Pereira, F. C.; Ge, X.; Kristensen, J. M.; Kirkegaard, R. H.; Maritsch, K.; Zu, Y.; Decorte, M.; Hausmann, B.; Berry, D.; Wasmund, K.; Schintlmeister, A.; Boettcher, T.; Cheng, J.-X.; Wagner, M.
10.1101/2023.11.12.566429 — microbiology — Posted on 2023-11-12
3024 Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent anti-PD-L1- and anti-NKG2A-based adjuvant immunotherapy
Patin, E. C.; Nenclares, P.; Chan Wah Hak, C.; Dillon, M. T.; Patrikeev, A.; McLaughlin, M.; Grove, L.; Foo, S.; Soliman, H.; Barata, J. P.; Marsden, J.; Baldock, H.; Roulstone, V.; Kyula, J.; Burley, A.; Hubbard, L. C.; Pedersen, M.; Smith, S. A.; Clancy-thompson, E.; Melcher, A. A.; Ono, M.; Rullan, A.; Harrington, K. J.
10.1101/2023.11.08.566202 — immunology — Posted on 2023-11-12
3025 TNFa hinders FGF4 efficacy to mitigate ALS astrocyte dysfunction and cGAS-STING pathway-induced innate immune reactivity
Velasquez, E.; savchenko, e.; marmolejo, s.; challuau, d.; aebi, a.; Pomeshchik, Y.; Lamas, N.; Vihinen, M.; Rezeli, m.; schneider, b.; Raoul, c.; roybon, l.
10.1101/2023.11.08.566131 — neuroscience — Posted on 2023-11-12
3026 miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice
Narayanan, R.; Levone, B. R.; Winterer, J.; Nanda, P.; Mueller, A.; Fiore, R.; germain, p. l.; Mihailovich, M.; Testa, G.; Schratt, G.
10.1101/2023.11.08.566242 — neuroscience — Posted on 2023-11-12
3027 Ammonia-oxidizing archaea and bacteria differentially contribute to ammonia oxidation in soil under precipitation gradients and land legacy
Sarkar, S.; Kazarina, A.; Hansen, P. M.; Ward, K.; Hargreaves, C.; Reese, N.; Ran, Q.; Kessler, W.; de Souza, L. F. T.; Loecke, T. D.; Sarto, M. V. M.; Rice, C. W.; Zeglin, L. H.; Sikes, B. A.; Lee, S. T. M.
10.1101/2023.11.08.566028 — bioinformatics — Posted on 2023-11-12
3029 Development of supramolecular anticoagulants with on-demand reversibility
Dockerill, M.; Ford, D. J.; Angerani, S.; Alwis, I.; Ripoll-Rozada, J.; Smythe, R. E.; Liu, J. S. T.; Barbosa Pereira, P. J.; Jackson, S. P.; Payne, R. J.; Winssinger, N.
10.1101/2023.11.12.566735 — biochemistry — Posted on 2023-11-12
3030 Urine proteomic analysis of patients with schizophrenia
Zhao, C.; Dong, F.; Zhou, F.; Huan, Y.; Gao, Y.; Yang, J.
10.1101/2023.11.11.566683 — biochemistry — Posted on 2023-11-12
3031 Conserved 5-methyluridine tRNA modification modulates ribosome translocation
Jones, J. D.; Franco, M. K.; Tardu, M.; Smith, T. J.; Snyder, L. R.; Eyler, D. E.; Polikanov, Y. S.; Kennedy, R. T.; Niederer, R. O.; Koutmou, K. S.
10.1101/2023.11.12.566704 — biochemistry — Posted on 2023-11-12
3034 Suppression of progesterone by influenza A virus mediates adverse maternal and fetal outcomes in mice
Creisher, P. S.; Parish, M. A.; Lei, J.; Liu, J.; Perry, J. L.; Campbell, A. D.; Sherer, M. L.; Burd, I.; Klein, S. L.
10.1101/2023.09.11.557146 — microbiology — Posted on 2023-11-12
3035 The SARS-CoV-2 Omicron sub-variant BA.2.86 is attenuated in hamsters
Herder, V.; Mendonca, D. C.; Upfold, N.; Furnon, W.; Kerr, K.; Ilia, G.; Allan, J.; Sigal, A.; Patel, A. H.; Palmarini, M.
10.1101/2023.11.10.566576 — microbiology — Posted on 2023-11-12
3039 OprF functions as a latch to direct Outer Membrane Vesicle release in Pseudomonas aeruginosa.
Mathur, S.; Erickson, S. K.; Goldberg, L. R.; Hills, S.; Radin, A. G.; Schertzer, J. W.
10.1101/2023.11.12.566662 — microbiology — Posted on 2023-11-12
3043 Ultrasonic reporters of calcium for deep tissue imaging of cellular signals
Jin, Z.; Lakshmanan, A.; Zhang, R.; Tran, T. A.; Rabut, C.; Dutka, P.; Duan, M.; Hurt, R. C.; Malounda, D.; Yao, Y.; Shapiro, M. G.
10.1101/2023.11.09.566364 — bioengineering — Posted on 2023-11-12
3044 Improving Hi-C contact matrices using genome graphs
Shen, Y.; Yu, L.; Qiu, Y.; Zhang, T.; Kingsford, C.
10.1101/2023.11.08.566275 — genomics — Posted on 2023-11-12
3045 MiR-221/222-enriched ADSC-exosome mitigates PM exposure-exacerbated cardiac ischemia/reperfusion injury through the modulation of the BNIP3/LC3B/PUMA pathway
Lee, T.-L.; Shen, W.-C.; Chen, Y.-C.; Lai, T.-C.; Lin, S.-R.; Lin, S.-W.; Yu, I.-S.; Yeh, Y.-H.; Li, T.-K.; Lee, I.-T.; Lee, C.-W.; Chen, Y.-L.
10.1101/2023.11.10.566671 — cell biology — Posted on 2023-11-12
3048 Cell Tree Rings: the structure of somatic evolution as a human aging timer
Csordas, A.; Sipos, B.; Kurucova, T.; Volfova, A.; Zamola, F.; Tichy, B.; Hicks, D. G.
10.1101/2022.12.14.520419 — genomics — Posted on 2023-11-12
3049 Probe capture enrichment sequencing of amoA genes discloses diverse ammonia-oxidizing archaeal and bacterial populations
Hiraoka, S.; Ijichi, M.; Takeshima, H.; Kumagai, Y.; Yang, C.-C.; Makabe-Kobayashi, Y.; Fukuda, H.; Yoshizawa, S.; Iwasaki, W.; Kogure, K.; Shiozaki, T.
10.1101/2023.04.10.536224 — microbiology — Posted on 2023-11-12
3050 New learning principles emerge from biomimetic computational primitives
Pathak, A.; Brincat, S. L.; Organtzidis, H.; Strey, H. H.; Senneff, S.; Antzoulatos, E. G.; Mujica-Parodi, L. R.; Miller, E. K.; Granger, R.
10.1101/2023.11.06.565902 — neuroscience — Posted on 2023-11-12
3053 GADD34 mRNA turnover controls the molecular memory of cellular stress experience
Magg, V.; Manetto, A.; Kopp, K.; Welsch, J.; Eke, L.; Kallenberger, S. M.; Haucke, V.; Locker, N.; Stoecklin, G.; Ruggieri, A.
10.1101/2023.11.11.566686 — cell biology — Posted on 2023-11-12
3055 A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice
Medeiros, D.; Ayala-Baylon, K.; Egido-Betancourt, H.; Miller, E.; Chapleau, C. A.; Robinson, H. A.; Phillips, M. L.; Yang, T.; Longo, F.; Li, W.; Pozzo-Miller, L.
10.1101/2023.11.09.566435 — neuroscience — Posted on 2023-11-12
3056 Axonal PLC-γ activity is required for BDNF long-distance signaling.
Moya-Alvarado, G.; Valero-Pena, X.; Aguirre-Soto, A.; Bronfman, F. C.
10.1101/2023.11.10.566602 — neuroscience — Posted on 2023-11-12
3058 Optimized protocols for RNA interference in Macrostomum lignano
Mouton, S.; Mougel, A.; Ustyantsev, K.; Dissous, C.; Melnyk, O.; Berezikov, E.; Vicogne, J.
10.1101/2023.11.09.565441 — developmental biology — Posted on 2023-11-11
3062 Maternal sterol 27-hydroxylase is crucial for securing fetal development
Suzuki, M.; Nakano, S.; Miharada, N.; Takei, H.; Prabhala, P.; van der Garde, M.; Müller, C.; Sigurdsson, V.; Aerken, M.; Saito, K.; Koide, S.; Westergren-Thorsson, G.; Magnusson, M.; Kakiyama, G.; Nittono, H.; Miharada, K.
10.1101/2023.11.08.566330 — developmental biology — Posted on 2023-11-12
3066 Covert RNA viruses in medflies differ in their mode of transmission and tissue tropism
Hernandez-Pelegrin, L.; Huditz, H. I.; Castillo, P. G.; de Ruijter, N. C. A.; van Oers, M. M.; Herrero, S.; Ros, V. I. D.
10.1101/2023.11.08.566245 — ecology — Posted on 2023-11-11
3067 Malaria parasite resistance to azithromycin is not readily transmitted by mosquitoes
Buchanan, H. D.; McConville, R.; Yeoh, L. M.; Duffy, M. F.; Boddey, J. A.; McFadden, G. I.; Goodman, C. D.
10.1101/2023.11.10.566666 — molecular biology — Posted on 2023-11-11
3069 Physiological variability in mitochondrial rRNA predisposes to metabolic syndrome
Pecina, P.; Cunatova, K.; Kaplanova, V.; Puertas-Frias, G.; Silhavy, J.; Tauchmannova, K.; Vrbacky, M.; Cajka, T.; Gahura, O.; Pravenec, M.; Houstek, J.; Mracek, T.; Pecinova, A.
10.1101/2023.11.08.566188 — physiology — Posted on 2023-11-11
3070 In vivo screening for toxicity-modulating drug interactions identifies antagonism that protects against ototoxicity in zebrafish
Bustad, E.; Mudrock, E.; Nilles, E. M.; McQuate, A.; Bergado, M.; Gu, A.; Galitan, L.; Gleason, N.; Ou, H. C.; Raible, D. W.; Hernandez, R. E.; Ma, S.
10.1101/2023.11.08.566159 — pharmacology and toxicology — Posted on 2023-11-11
3071 BioWiC: An Evaluation Benchmark for Biomedical Concept Representation
Rouhizadeh, H.; Nikishina, I.; Yazdani, A.; Bornet, A.; Zhang, B.; Ehrsam, J.; Gaudet-Blavignac, C.; Naderi, N.; Teodoro, D.
10.1101/2023.11.08.566170 — bioinformatics — Posted on 2023-11-11
3072 FLASHQuant: a fast algorithm for proteoform quantification in top-down proteomics
Kim, J.; Jeong, K.; Kaulich, P. T.; Winkels, K.; Tholey, A.; Kohlbacher, O.
10.1101/2023.11.08.566181 — bioinformatics — Posted on 2023-11-11
3077 A seven-sex species recognizes self and non-self mating-type via a novel protein complex
Yan, G.; Ma, Y.; Wang, Y.; Zhang, J.; Cheng, H.; Tan, F.; Wang, S.; Zhang, D.; Xiong, J.; Yin, P.; Miao, W.
10.1101/2023.11.08.566168 — genetics — Posted on 2023-11-11
3080 Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adenoviral expression of Ca2+ indicators
Masala, N.; Mittag, M.; Ambrad Giovannetti, E.; O'Neil, D. A.; Distler, F. J.; Rupprecht, P.; Helmchen, F.; Yuste, R.; Fuhrmann, M.; Beck, H.; Wenzel, M.; Kelly, T.
10.1101/2023.11.08.566169 — neuroscience — Posted on 2023-11-11
3081 Protocol for 3D Virtual Histology of Unstained Human Brain Tissue using Synchrotron Radiation Phase-Contrast Microtomography
Lee, J. Y.; Donato, S.; Mack, A. F.; Mattheus, U.; Tromba, G.; Longo, E.; D Amico, L.; Mueller, S.; Shiozawa, T.; Bause, J.; Scheffler, K.; Longo, R.; Hagberg, G. E.
10.1101/2023.11.08.566183 — neuroscience — Posted on 2023-11-11
3084 Structure of scavenger receptor SCARF1 and its interaction with lipoproteins
Wang, Y.; Xu, F.; Li, G.; Cheng, C.; Yu, B.; Zhang, Z.; Kong, D.; Chen, F.; Liu, Y.; Fang, Z.; Cao, L.; Yang, Y.; Gu, Y.; He, Y.
10.1101/2023.11.08.566208 — biophysics — Posted on 2023-11-11
3087 Insulin and Exercise-induced Phosphoproteomics of Human Skeletal Muscle Identify REPS1 as a New Regulator of Muscle Glucose Uptake
Larsen, J. K.; Lindqvist, C. B.; Jessen, S.; Garcia-Urena, M.; Ehrlich, A.; Schlabs, F.; Quesada, J. P.; Schmalbruch, J.; Small, L.; Thomassen, M.; Lemminger, A. K.; Eibye, K.; Gonzalez-Franquesa, A.; Stidsen, J. v.; hoejlund, k.; Kilpelainen, T.; Bangsbo, J.; Treebak, J. T.; Hostrup, M.; Deshmukh, A. S.
10.1101/2023.11.10.566644 — biochemistry — Posted on 2023-11-11
3090 Holistic in silico developability assessment of novel classes of small proteins using publicly available sequence-based predictors
Pais, D. A. M.; Mayer, J.-P. A.; Felderer, K.; Batalha, M. B.; Eichner, T.; Santos, S. T.; Kumar, R.; Silva, S. D.; Kaufmann, H.
10.1101/2023.11.10.566515 — biochemistry — Posted on 2023-11-11
3095 Modifications in the T arm of tRNA globally determine tRNA maturation, function and cellular fitness
Schultz, S. K.; Katanski, C. D.; Halucha, M.; Pena, N.; Fahlman, R. P.; Pan, T.; Kothe, U.
10.1101/2023.11.11.566336 — molecular biology — Posted on 2023-11-11
3099 Use of Multiple Pharmacodynamic Measures to Deconstruct the Nix-TB Regimen in a Short-Course Murine Model of Tuberculosis
Lyons, M. A.; Obregon-Henao, A.; Ramey, M. E.; Bauman, A. A.; Pauly, S.; Rossmassler, K.; Reid, J.; Karger, B.; Walter, N. D.; Robertson, G. T.
10.1101/2023.11.08.566205 — pharmacology and toxicology — Posted on 2023-11-11
3100 DeMixSC: a deconvolution framework that uses single-cell sequencing plus a small benchmark dataset for improved analysis of cell-type ratios in complex tissue samples
Guo, S.; Liu, X.; Cheng, X.; Jiang, Y.; Ji, S.; Liang, Q.; Koval, A.; Li, Y.; Owen, L. A.; Kim, I. K.; Aparicio, A.; Shen, J. P.; Kopetz, S.; Weinstein, J. N.; DeAngelis, M. M.; Chen, R.; Wang, W.
10.1101/2023.10.10.561733 — bioinformatics — Posted on 2023-11-11
3103 Cleavage of protein kinase c δ by caspase-3 mediates pro-inflammatory cytokine-induced apoptosis in pancreatic islets
Collins, J.; Piscopio, R. A.; Reyland, M. E.; Johansen, C. G.; Benninger, R. K.; Farnsworth, N. L.
10.1101/2022.07.20.500512 — cell biology — Posted on 2023-11-11
3106 Modeling the effect of spatial structure on solid tumor evolution and ctDNA composition
Rachman, T.; Bartlett, D.; Laframboise, W.; Wagner, P.; Schwartz, R.; Carja, O.
10.1101/2023.11.10.566658 — cancer biology — Posted on 2023-11-11
3107 2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer
Coy, S.; Cheng, B.; Lee, J. S.; Rashid, R.; Browning, L.; Xu, Y.; Chakrabarty, S. S.; Yapp, C.; Chan, S.; Tefft, J. B.; Spektor, A.; Ligon, K. L.; Baker, G. J.; Pellman, D.; Sorger, P. K.; Santagata, S.
10.1101/2023.11.07.566063 — cancer biology — Posted on 2023-11-11
3109 Stress granule formation helps to mitigate neurodegeneration
Glineburg, M. R.; Yildirim, E.; Gomez, N.; Li, X.; Pak, J.; Altheim, C.; Waksmacki, J.; McInerney, G. M.; Barmada, S.; Todd, P. K.
10.1101/2023.11.07.566060 — neuroscience — Posted on 2023-11-11
3110 Progressive degeneration in a new Drosophila model of Spinocerebellar Ataxia type 7
Sujkowski, A.; Ranxhi, B.; Prifti, M. V.; Alam, N.; Todi, S. V.; Tsou, W.-L.
10.1101/2023.11.07.566106 — neuroscience — Posted on 2023-11-11
3111 Rapid spectrophotometric detection for optimized production of landomycins and characterization of their therapeutic potential
Chappell, T. C.; Maiello, K. G.; Tierny, A. J.; Yanagi, K.; Lee, J. A.; Lee, K.; Mace, C. R.; Bennett, C. S.; Nair, N. U.
10.1101/2023.11.07.566088 — bioengineering — Posted on 2023-11-11
3114 Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.
Nelson, A. N.; Shen, X.; Venkatayogi, S.; Zhang, S.; Ozorowski, G.; Dennis, M.; Sewall, L. M.; Milligan, E.; Davis, D.; Cross, K.; Chen, Y.; van Schooten, J.; Eudaily, J.; Isaac, J.; Memon, S.; Weinbaum, C.; Stanfield-Oakley, S.; Byrd, A.; Chutkan, S.; Berendam, S.; Cronin, K.; Yasmeen, A.; Alam, S. M.; LeBranche, C.; Rogers, K.; Shirreff, L.; Cupo, A.; Derking, R.; Villinger, F.; Klasse, P. J.; Ferrari, G.; Williams, W. B.; Hudgens, M. G.; Ward, A. B.; Montefiori, D. C.; VanRompay, K.; Wiehe, K.; Moore, J. P.; Sanders, R. W.; De Paris, K.; Permar, S. R.
10.1101/2023.11.07.565306 — immunology — Posted on 2023-11-11
3116 Cortical high gamma power relates to movement speed and is disproportionately reduced after stroke
Haverland, B.; Timmsen, L. S.; Wolf, S.; Stagg, C. J.; Frontzkowski, L.; Feldheim, J.; Higgen, F. L.; Gerloff, C.; Schulz, R.; Schneider, T. R.; Schwab, B. C.; Quandt, F.
10.1101/2023.11.07.565934 — neuroscience — Posted on 2023-11-11
3117 Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton
Beedle, A. E. M.; Jaganathan, A.; Albajar-Sigales, A.; Yavitt, F. M.; Bera, K.; Andreu, I.; Granero-Moya, I.; Zalvidea, D.; Kechagia, Z. M.; Wiche, G.; Trepat, X.; Ivaska, J.; Anseth, K. S.; Shenoy, V.; Roca-Cusachs, P.
10.1101/2023.11.08.566191 — biophysics — Posted on 2023-11-11
3120 The genome and population genomics of allopolyploid Coffea arabica reveal the diversification history of modern coffee cultivars
Salojarvi, J.; Rambani, A.; Yu, Z.; Guyot, R.; Strickler, S.; Lepelley, M.; Wang, C.; Rajaraman, S.; Rastas, P.; Zheng, C.; Munoz, D. S.; Meidanis, J.; Paschoal, A. R.; Bawin, Y.; Krabbenhoft, T.; Wang, Z. Q.; Fleck, S.; Aussel, R.; Bellanger, L.; Charpagne, A.; Fournier, C.; Kassam, M.; Lefebvre, G.; Metairon, S.; Moine, D.; Rigoreau, M.; Stolte, J.; Hamon, P.; Couturon, E.; Tranchant-Dubreuil, C.; Mukherjee, M.; Lan, T.; Engelhardt, J.; Stadler, P.; De Lemos, S. C.; Suzuki, S. I.; Sumirat, U.; Ching Man, W.; Dauchot, N.; Orozco-Arias, S.; Garavito, A.; Kiwuka, C.; Musoli, P.; Nalukenge, A.;
10.1101/2023.09.06.556570 — genomics — Posted on 2023-11-11
3123 FFCM-MRF: An accurate and generalizable cerebrovascular segmentation pipeline for humans and rhesus monkeys based on TOF-MRA
Cui, Y.; Huang, H.; Liu, J.; Zhao, M.; Li, C.; Han, X.; Luo, N.; Gao, J.; Yan, D.; Zhang, C.; Jiang, T.; Yu, S.
10.1101/2023.11.07.566142 — neuroscience — Posted on 2023-11-11
3124 A high-density diffuse optical tomography dataset of naturalistic viewing
Sherafati, A.; Bajracharya, A.; Jones, M.; Speh, E.; Munsi, M.; Lin, C.-H. P.; Fishell, A. K.; Hershey, T.; Eggebrecht, A. T.; Culver, J. P.; Peelle, J. E.
10.1101/2023.11.07.565473 — neuroscience — Posted on 2023-11-11
3125 Memory control deficits in the sleep-deprived human brain
Harrington, M. O.; Karapanagiotidis, T.; Phillips, L.; Smallwood, J.; Anderson, M. C.; Cairney, S. A.
10.1101/2023.11.07.565941 — neuroscience — Posted on 2023-11-11
3127 High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue
Zhang, N.; Harbers, L.; Simonetti, M.; Diekmann, C.; Verron, Q.; Berrino, E.; Bellomo, S. E.; Longo, G. M. C.; Ratz, M.; Schultz, N.; Tarish, F.; Su, P.; Han, B.; Wang, W.; Onorato, S.; Giordano, S.; Yang, Q.; Sapino, A.; Frisen, J.; Alkass, K.; Druid, H.; Roukos, V.; Helleday, T.; Marchio, C.; Bienko, M.; Crosetto, N.
10.1101/2023.11.07.566123 — cancer biology — Posted on 2023-11-11
3128 Dissecting Multiparametric Cerebral Hemodynamics using Integrated Ultrafast Ultrasound and Multispectral Photoacoustic Imaging
Chen, H.; Mirg, S.; Gaddale, P.; Agrawal, S.; Li, M.; Nguyen, V.; Xu, T.; Li, Q.; Liu, J.; Tu, W.; Liu, X.; Drew, P. J.; Zhang, N.; Gluckman, B. J.; Kothpalli, S.-R.
10.1101/2023.11.07.566048 — bioengineering — Posted on 2023-11-11
3129 UV damage induces production of mitochondrial DNA fragments with specific length profiles
Waneka, G.; Stewart, J.; Anderson, J.; Wilusz, J.; Argueso, J. L.; Sloan, D. B.
10.1101/2023.11.07.566130 — genetics — Posted on 2023-11-11
3134 A single Microcoleus species causes benthic cyanotoxic blooms worldwide
Junier, P.; Cailleau, G.; Fatton, M.; Udriet, P.; Hashmi, I.; Bregnard, D.; Corona-Ramirez, A.; di Francesco, E.; Kuhn, T.; Mangia, N.; Zhioua, S.; Hunkeler, D.; Bindschedler, S.; Sieber, S.; Gonzalez, D.
10.1101/2023.10.13.562201 — microbiology — Posted on 2023-11-11
3137 Abstract representations emerge in human hippocampal neurons during inference behavior
Courellis, H. S.; Minxha, J.; Ramirez Cardenas, A.; Kimmel, D. L.; Reed, C. M.; Valiante, T. A.; Salzman, C. D.; Mamelak, A. N.; Adolphs, R.; Fusi, S.; Rutishauser, U.
10.1101/2023.11.10.566490 — neuroscience — Posted on 2023-11-11
3139 Understanding Campylobacter coli isolates from the Vietnamese meat production network; a pilot study
Lehri, B.; Navoly, G.; Corser, A.; Nasher, F.; Willcocks, S.; Ngoc, P. T.; Wren, B. W.; Huong, L. Q.; Stabler, R. A.
10.1101/2023.11.10.566519 — microbiology — Posted on 2023-11-11
3140 Environmental enrichment and physical exercise prevent stress-induced behavioral and blood-brain barrier alterations via Fgf2
Paton, S. E.; Solano, J. L.; Collignon, A.; Richer, E.; Coulombe-Rozon, F.; Dion-Albert, L.; Binder, L. B.; Dudek, K. A.; Cadoret, A.; Signature Consortium, ; Lebel, M.; Menard, C.
10.1101/2023.11.08.566229 — neuroscience — Posted on 2023-11-11
3141 Functional parcellation of the neonatal brain
Myers, M. J.; Labonte, A. K.; Gordon, E. M.; Laumann, T. O.; Tu, J. C.; Wheelock, M. D.; Nielsen, A. N.; Schwarzlose, R.; Camacho, M. C.; Warner, B. B.; Raghuraman, N.; Luby, J. L.; Barch, D. M.; Fair, D. A.; Petersen, S. E.; Rogers, C. E.; Smyser, C. D.; Sylvester, C. M.
10.1101/2023.11.10.566629 — neuroscience — Posted on 2023-11-11
3144 The mitochondrial calcium uniporter is necessary for synaptic plasticity and proper mitochondrial morphology and distribution in the distal dendrites of CA2 neurons
Pannoni, K. E.; Fischer, Q. S.; Tarannum, R.; Cawley, M. L.; Alsalman, M. M.; Acosta, N.; Ezigbo, C.; Gil, D. V.; Campbell, L. A.; Farris, S.
10.1101/2023.11.10.566606 — neuroscience — Posted on 2023-11-11
3145 Neuronal PAS domain 1 identifies a major subpopulation of wakefulness-promoting GABAergic neurons in basal forebrain
Troppoli, T. A.; Yang, C.; Katsuki, F.; Uygun, D. S.; Lin, I.; Aguilar, D. D.; Spratt, T.; Basheer, R.; McNally, J. M.; Chan, C. S.; McKenna, J. T.; Brown, R. E.
10.1101/2023.11.09.566065 — neuroscience — Posted on 2023-11-11
3147 Human organoid modeling of congenital malformations caused by RFX6 mutations reveal an essential role for this transcription factor in establishing and maintaining duodenal identity upstream of PDX1
Wells, J. M.; Sanchez, G.; Rankin, S. A.; Paul, E.; McCauley, H. A.; Kechele, D.; Enriquez, J.; Jones, N.-H.; Greeley, S. A.; Letourneau-Friedberg, L.; Zorn, A. A.; Krishnamurthy, M.
10.1101/2023.11.09.566480 — developmental biology — Posted on 2023-11-11
3148 Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression
Zhang, Q.-X.; Liu, T.; Guo, X.; Zhen, J.; Yang, M.-y.; Khederzadeh, S.; Zhou, F.; Han, X.; Zheng, Q.; Jia, P.; Ding, X.; He, M.; Zou, X.; Zhang, H.; He, J.; Zhu, X.; Lu, D.; Chen, H.; Zeng, C.; Liu, F.; Zheng, H.-F.; Liu, S.; Xu, H.; Chen, G.-B.
10.1101/2022.10.18.512407 — genetics — Posted on 2023-11-11
3150 A non-toxic equinatoxin-II reveals the dynamics of sphingomyelin in the cytosolic leaflet of the plasma membrane
Mori, T.; Niki, T.; Uchida, Y.; Mukai, K.; Kuchitsu, Y.; Kishimoto, T.; Makino, A.; Kobayashi, T.; Arai, H.; Yokoata, Y.; Taguchi, T.; Suzuki, K. G. N.
10.1101/2023.11.10.566659 — cell biology — Posted on 2023-11-10
3151 Minimization of the E. coli ribosome, aided and optimized by community science
Tangpradabkul, T.; Palo, M. Z.; Townley, J.; Hsu, K. B.; Eterna Participants, ; Smaga, S.; Das, R.; Schepartz, A.
10.1101/2023.11.09.566451 — synthetic biology — Posted on 2023-11-10
3154 Teosinte Pollen Drive guides maize diversification and domestication by RNAi
Berube, B.; Ernst, E.; Cahn, J.; Roche, B.; de Santis Alves, C.; Lynn, J.; Scheben, A.; Siepel, A.; Ross-Ibarra, J.; Kermicle, J.; Martienssen, R. A.
10.1101/2023.07.12.548689 — plant biology — Posted on 2023-11-10
3155 The genomes and epigenomes of aquatic plants (Lemnaceae) promote triploid hybridization and clonal reproduction
Ernst, E.; Abramson, B.; Acosta, K.; Hoang, P. T.; Mateo-Elizalde, C.; Schubert, V.; Pasaribu, B.; Hartwick, N.; Colt, K.; Aylward, A. J.; Lee, S. C.; Ramu, U.; Birchler, J. A.; Schubert, I.; Lam, E.; Michael, T. P.; Martienssen, R. A.
10.1101/2023.08.02.551673 — plant biology — Posted on 2023-11-10
3156 Light induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo
Velasquez Pulgarin, D. A.; Pelo, N.; Ferrandiz, L.; Trselic, T.; Nyberg, W. A.; Bowlin, G. L.; Espinosa, A.
10.1101/2023.11.09.566272 — bioengineering — Posted on 2023-11-10
3157 Combinatorial selective ER-phagy remodels the ER during neurogenesis
Hoyer, M. J.; Capitanio, C.; Smith, I. R.; Paoli, J. C.; Bieber, A.; Jiang, Y.; Paulo, J. A.; Gonzalez-Lozano, M. A.; Baumeister, W.; Wilfling, F.; Schulman, B. A.; Harper, W.
10.1101/2023.06.26.546565 — cell biology — Posted on 2023-11-10
3159 Cerebellar interneuron activity is triggered by reach endpoint during learning of a complex locomotor task
Andrianarivelo, A.; Stein, H.; Gabillet, J.; Batifol, C.; Jalil, A.; Cayco Gajic, N. A.; Graupner, M.
10.1101/2023.10.10.561690 — neuroscience — Posted on 2023-11-10
3164 The trade-off between growth and risk in Kelly's gambling and beyond
Lacoste, D.; Dinis, L.; Cavallero, S.; Pugatch, R.; Rousselot, A.
10.1101/2023.11.07.566039 — biophysics — Posted on 2023-11-10
3165 Integrated analysis of baseline protein expression in pig tissues
Wang, S.; Collins, A.; Prakash, A.; Fexova, S.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2023.11.07.566009 — bioinformatics — Posted on 2023-11-10
3167 Trinucleotide mRNA cap analog N6-benzylated at the site of posttranscriptional m6Am mark facilitates mRNA purification and confers superior translational properties in vitro and in vivo
Warminski, M.; Trepkowska, E.; Smietanski, M.; Sikorski, P. J.; Baranowski, M. R.; Bednarczyk, M.; Kedzierska, H.; Majewski, B.; Mamot, A.; Papiernik, D.; Popielec, A.; Serwa, R.; Shimanski, B. A.; Sklepkiewicz, P.; Sklucka, M.; Sokolowska, O.; Spiewla, T.; Toczydlowska-Socha, D.; Warminska, Z.; Wolosewicz, K.; Zuberek, J.; Mugridge, J. S.; Nowis, D.; Golab, J.; Jemielity, J.; Kowalska, J.
10.1101/2023.11.10.566532 — biochemistry — Posted on 2023-11-10
3168 Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of ZDBF2
Kobayashi, H.; Igaki, T.; Kumamoto, S.; Tanaka, K.; Takashima, T.; Suzuki, S.; Hayashi, M.; Renfree, M. B.; Kawahara, M.; Saito, S.; Kobayashi, T.; Nagashima, H.; Nakano, K.; Matsunari, H.; Uchikura, A.; Kiyonari, H.; Kaneko, M.; Imai, H.; Nakabayashi, K.; Lorincz, M. C.; Kurimoto, K.
10.1101/2023.10.30.564869 — genomics — Posted on 2023-11-10
3170 Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis
Ito, M.; Yun, Y.; Kulkarni, D. S.; Sandhu, S.; Nunez, B.; Hu, L.; Lee, K.; Lim, N.; Hirota, R.; Prendergast, R.; Huang, C.; Huang, I.; Hunter, N.
10.1101/2023.11.07.566091 — genetics — Posted on 2023-11-10
3171 The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk
Liang, Q.; Jiang, Y.; Shieh, A. W.; Zhou, D.; Chen, R.; Wang, F.; Xu, M.; Niu, M.; Wang, X.; Pinto, D.; Wang, Y.; Cheng, L.; Vadukapuram, R.; Zhang, C.; Grennan, K.; Giase, G.; The PsychENCODE Consortium, ; White, K. P.; Peng, J.; Li, B.; Liu, C.; Chen, C.; Wang, S. H.
10.1101/2023.06.04.543603 — genetics — Posted on 2023-11-10
3174 OOCYTE AND EMBRYO CULTURE UNDER OIL PROFOUNDLY ALTERS EFFECTIVE CONCENTRATIONS OF SMALL MOLECULE INHIBITORS
Remillard Labrosse, G.; Cohen, S.; Boucher, E.; Gagnon, K.; Vasilev, F.; Mihajlovic, A. I.; FitzHarris, G.
10.1101/2023.11.10.566607 — developmental biology — Posted on 2023-11-10
3177 Characterisation and correction of polarisation effects in fluorescently labelled fibres
Aggarwal, N.; Marsh, R.; Marcotti, S.; Shaw, T. J.; Stramer, B.; Cox, S.; Culley, S.
10.1101/2023.11.10.566047 — cell biology — Posted on 2023-11-10
3179 The modified RNA base acp3U is an attachment site for N-glycans in glycoRNA
Xie, Y.; Hemberger, H.; Till, N. A.; Chai, P.; Watkins, C.; Lebedenko, C. G.; Caldwell, R. M.; George, B.; Bertozzi, C. R.; Garcia, B. A.; Flynn, R. A.
10.1101/2023.11.06.565735 — molecular biology — Posted on 2023-11-10
3180 Coordinated immune dysregulation in Juvenile Dermatomyositis revealed by single-cell genomics
Rabadam, G.; Wibrand, C.; Flynn, E.; Hartoularos, G. C.; Sun, Y.; Ye, C. J.; Kim, S.; Gartner, Z. J.; Sirota, M.; Neely, J.
10.1101/2023.11.07.566033 — immunology — Posted on 2023-11-10
3182 Two common and distinct forms of variation in human functional brain networks
Dworetsky, A.; Seitzman, B. A.; Adeyemo, B.; Nielsen, A. N.; Hatoum, A. S.; Smith, D. M.; Nichols, T. E.; Neta, M.; Petersen, S. E.; Gratton, C.
10.1101/2021.09.17.460799 — neuroscience — Posted on 2023-11-10
3183 Hypoxia evokes a sequence of raphe-pontomedullary network operations for inspiratory drive amplification and gasping
NUDING, S. C.; Segers, L. S.; Iceman, K.; O'Connor, R.; Dean, J. B.; Valarezo, P. A.; Shuman, D.; Solomon, I. C.; Bolser, D. C.; Morris, K. F.; Lindsey, B. G.
10.1101/2023.11.07.566027 — neuroscience — Posted on 2023-11-10
3185 Double mutation of open syntaxin and UNC-18 P334A leads to excitatory-inhibitory imbalance and impairs multiple aspects of C. elegans behavior
Huang, M.; Wang, Y.; Chow, C. H.; Stepien, K.; Indrawinata, K.; Xu, J.; Argiropoulos, P.; Xie, X.; Sugita, K.; Tien, C.-W.; Lee, S.; Monnier, P. P.; Rizo, J.; Gao, S.; Sugita, S.
10.1101/2023.08.18.553709 — neuroscience — Posted on 2023-11-10
3186 Nanoscale imaging of pT217-tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration
Datta, D.; Perone, I.; Wijegunawardana, D.; Liang, F.; Morozov, Y. M.; Arellano, J.; Duque, A.; Xie, Z.; van Dyck, C. H.; Arnsten, A. F.
10.1101/2023.11.07.566046 — neuroscience — Posted on 2023-11-10
3187 Adenosine triggers early astrocyte reactivity that provokes microglial activation and drives the pathogenesis of sepsis-associated encephalopathy
Guo, Q.; Gobbo, D.; Zhao, N.; Liu, Q.; Fang, L.-P.; Gampfer, T. M.; Meyer, M. R.; Bai, X.; Bian, S.; Scheller, A.; Kirchhoff, F.; Huang, W.
10.1101/2023.10.30.563169 — neuroscience — Posted on 2023-11-10
3188 Targeting NRP1 with EG00229 induces neurovascular permeability
Dragoni, S.; Brash, J. T.; Fantin, A.; Burridge, C.; Denti, L.; Turowski, P.; Ruhrberg, C.
10.1101/2023.11.07.564946 — physiology — Posted on 2023-11-10
3189 Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells
Zhang, Y.; Tedja, R.; Millman, M.; Wong, T.; Fox, A.; Chehade, H.; Gershater, M.; Adzibolosu, N.; Gogoi, R.; Anderson, M.; Rutherford, T.; Zhang, Z.; Chopp, M.; Mor, G.; Alvero, A. B.
10.1101/2023.11.07.566022 — cancer biology — Posted on 2023-11-10
3192 Do chemical language models provide a better compound representation?
Torrisi, M.; Asadollahi, S.; de la Vega de Leon, A.; Wang, K.; Copeland, W.
10.1101/2023.11.07.566025 — bioinformatics — Posted on 2023-11-10
3193 TCCIA: A Comprehensive Resource for Exploring CircRNA in Cancer Immunotherapy
Wang, S.; Xiong, Y.; Zhang, Y.; Wang, H.; Chen, M.; Li, J.; Luo, P.; Luo, Y.-H.; Hecht, M.; Frey, B.; Gaipl, U. S.; Li, X.; Zhao, Q.; Ma, H.; Zhou, J.-G.
10.1101/2023.08.24.554049 — bioinformatics — Posted on 2023-11-10
3197 Computationally Driven Discovery and Characterization of SIRT3 Activating Compounds that Fully Recover Catalytic Activity under NAD+ Depletion
Guan, X.; Upadhyay, A.; Dumpati, R. K.; Munshi, S.; Roy, S.; Chall, S.; Rahnamoun, A.; Reverdy, C.; Errasti, G.; Delacroix, T.; Ghosh, A.; Chakrabarti, R.
10.1101/2023.11.09.566481 — biochemistry — Posted on 2023-11-10
3200 Clock driven waves of Tbx6 expression prefigure somite boundaries
Venzin, O. F.; Jollivet, C.; Chiaruttini, N.; Rosspopoff, O.; Helsens, C.; Morelli, L. G.; Uriu, K.; Oates, A. C.
10.1101/2023.11.09.566373 — developmental biology — Posted on 2023-11-10
3201 Inter-phylum circulation of a beta-lactamase - encoding gene: a rare but observable event
GSCHWIND, R.; Petitjean, M.; Fournier, C.; Lao, J.; Clermont, O.; Nordmann, P.; Mellmann, A.; Denamur, E.; Poirel, L.; RUPPE, E.
10.1101/2023.11.10.566511 — microbiology — Posted on 2023-11-10
3203 Metabolic rewiring compensates for the loss of glutamate and aspartate biosynthesis in Bacillus subtilis
Mardoukhi, M. S.; Rapp, J.; Irisarri, I.; Gunka, K.; Link, H.; Marienhagen, J.; de Vries, J.; Stuelke, J.; Commichau, F. M.
10.1101/2023.11.10.566560 — microbiology — Posted on 2023-11-10
3205 Tick extracellular vesicles impair epidermal homeostasis through immune-epithelial networks during hematophagy
Marnin, L.; Bogale, H.; Laukaitis-Yousey, H.; Valencia, L.; Rolandelli, A.; O'Neal, A.; Ferraz, C.; Schmitter-Sanchez, A.; Bencosme Cuevas, E.; Nguyen, T.-T.; Leal-Galvan, B.; Rickert, D.; Bruno, V. M.; Mendes, M. T.; Samaddar, S.; Butler, L. R.; Singh, N.; Cabrera Paz, F.; Oliver, J.; Jameson, J.; Munderloh, U.; Oliva Chavez, A.; Mulenga, A.; Park, S.; Serre, D.; Pedra, J. H. F.
10.1101/2023.11.10.566612 — microbiology — Posted on 2023-11-10
3207 A systematic screening assay identifies efficient small guide RNAs for CRISPR activation
Arvidsson, E.; Lobo, D. D.; Sabarese, E.; Duarte, F.; Nobre, R. J.; Lundberg, C.; Quintino, L.
10.1101/2023.11.10.566523 — molecular biology — Posted on 2023-11-10
3208 Ablation of telomerase reverse transcriptase in Leishmania major results in a senescent-like phenotype and loss of infectivity
Shiburah, M. E.; De Oliveira, B. C. D.; Endalamaw, H. B.; Silva, D. A.; Assis, L. H. d. C.; Barreto, R. M.; Batista, M. M.; Soeiro, M. d. N. C.; Menozzi, B. D.; Langoni, H.; Aoki, J. I.; Coelho, A. C.; CANO, M. I. N.
10.1101/2023.11.10.566596 — molecular biology — Posted on 2023-11-10
3210 The impact of knocking out the Leishmania major telomerase RNA (LeishTER): from altered cell proliferation to decreased parasite infectivity
de Oliveira, B. C. D.; Shiburah, M. E.; Assis, L. H. d. C.; Fontes, V. S.; Gallo-Francisco, P. H.; Giorgio, S.; Batista, M. M.; Menna-Barreto, R. F. S.; Soeiro, M. d. N. C.; Aoki, J. I.; Coelho, A. C.; CANO, M. I. N.
10.1101/2023.11.10.566567 — molecular biology — Posted on 2023-11-10
3212 Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination
Doran, P. R.; Fomin-Thunemann, N.; Tang, R. P.; Zimmerman, B.; Kilic, K.; Martin, E. A.; Kura, S.; Fisher, H. P.; Chabbott, G.; Herbert, J.; Jiang, J. X.; Sakadzic, S.; Boas, D. A.; Devor, A.; Chen, I. A.; Thunemann, M.
10.1101/2023.11.07.566086 — neuroscience — Posted on 2023-11-10
3213 Comparison of radiography and computed tomography for condylar fracture risk assessment in Thoroughbred racehorses
Irandoust, S.; O'Neil, L. M.; Stevenson, C. M.; Franseen, F. M.; Ramzan, P. H. L.; Powell, S. E.; Brounts, S. H.; Loeber, S. J.; Ergun, D. L.; Whitton, R. C.; Henak, C. R.; Muir, P.
10.1101/2023.11.09.566089 — physiology — Posted on 2023-11-10
3216 Age and anatomical region related differences in vascularization of the porcine meniscus using micro-computed tomography imaging
Karjalainen, V.-P.; Herrera, V. R.; Modina, S.; Peretti, G.; Pallaoro, M.; Elkhouly, K.; Saarakkala, S.; Mobasheri, A.; Di Giancamillo, A.; Finnila, M. A. J.
10.1101/2023.11.08.565772 — biophysics — Posted on 2023-11-10
3217 3D single-molecule super-resolution imaging of microfabricated fractal substrates for cell culture and self-referenced imaging
Cabriel, C.; Cordova-Castro, R. M.; Berenschot, E. J. W.; Davila-Lezama, A.; Pondman, K.; Le Gac, S.; Tas, N.; Susarrey-Arce, A.; Izeddin, I.
10.1101/2023.11.07.566090 — biophysics — Posted on 2023-11-10
3220 Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types
Miller, A. D. C.; Chowdhury, S. P.; Hanson, H. W.; Linderman, S. K.; Ghasemi, H. I.; Miller, W. D.; Morrissey, M. A.; Richardson, C.; Gardner, B. M.; Mukherjee, A.
10.1101/2023.11.07.566095 — bioengineering — Posted on 2023-11-10
3224 Temperature influences the excretion time and parasitic load of Trypanosoma cruzi in the Triatoma infestans vector
Alvarez-Duhart, B.; Clavijo-Baquet, S.; Valenzuela-Perez, L.; Maya, J. D.; Saavedra, M.; Ortiz, S.; Bacigalupo, A.; Munoz-San Martin, C.; Cattan, P.
10.1101/2023.11.08.566164 — ecology — Posted on 2023-11-10
3225 Prevalence of Avian Influenza Virus in Synanthropic Birds Associated with an Outbreak of Highly Pathogenic Strain EA/AM H5N1
Ringenberg, J. M.; Weir, K.; Humberg, L.; Voglewede, C.; Oswald, M.; Root, J. J.; Dilione, K.; Casey, E.; Milleson, M.; Linder, T.; Lenoch, J.
10.1101/2023.11.08.565892 — ecology — Posted on 2023-11-10
3227 A Novel human IL-23A Overexpressing Mouse Model of Systemic Lupus Erythematosus
CHRISTODOULOU-VAFEIADOU, E.; GEKA, C.; ILIOPOULOU, L.; NTARI, L.; DENIS, M. C.; KARAGIANNI, N.; KOLLIAS, G.
10.1101/2023.11.08.566163 — immunology — Posted on 2023-11-10
3228 A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis
Hashemi, E.; Srivastava, I.; Aguirre, A.; Kaushal, E.; Yoseph, E.; Awani, A.; Ryu, J. K.; Akassoglou, K.; Talebian, S.; Chu, P.; Pisani, L.; Musolino, P.; Steinman, L.; Doyle, K.; Robinson, W. H.; Sharpe, O.; Cayrol, R.; Orchard, P.; Lund, T.; Vogel, H.; Lenail, M.; Han, M.; Bonkowsky, J. P.; Van Haren, K. P.
10.1101/2023.11.07.564025 — neuroscience — Posted on 2023-11-10
3229 Identification and Pharmacological Targeting of Treatment-Resistant, Stem-like Breast Cancer Cells for Combination Therapy
Worley, J.; Noh, H.; You, D.; Turunen, M.; Ding, H.; Paull, E. O.; Griffen, A.; Grunn, A.; Zhang, M.; Guillan, K.; Bush, E.; Brosius, S.; Hibshoosh, H.; Mundi, P. S.; Sims, P.; Dalerba, P.; Dela Cruz, F. S.; Kung, A. L.; Califano, A.
10.1101/2023.11.08.562798 — systems biology — Posted on 2023-11-10
3230 Democratizing Protein Language Models with Parameter-Efficient Fine-Tuning
Sledzieski, S.; Kshirsagar, M.; Baek, M.; Berger, B.; Dodhia, R.; Lavista Ferres, J.
10.1101/2023.11.09.566187 — bioinformatics — Posted on 2023-11-10
3231 Opening the species box: What microscopic models of neutral speciation have to say about macroevolution
Couvert, E.; Bienvenu, F.; Duchamps, J.-J.; Erard, A.; Miro Pina, V.; Schertzer, E.; Lambert, A.
10.1101/2023.11.09.564915 — evolutionary biology — Posted on 2023-11-10
3232 Altered hippocampal activation in seizure-prone CACNA2D2 knockout mice
Danis, A.; Gallagher, A. A.; Anderson, A. N.; Isakharov, A.; Beeson, K. A.; Schnell, E.
10.1101/2023.11.08.565511 — neuroscience — Posted on 2023-11-10
3233 Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes
O'Connell, L. C.; Johnson, V.; Hutton, A. K.; Otis, J. P.; Murthy, A. C.; Liang, M. C.; Wang, S.-H.; Fawzi, N. L.; Mowry, K. L.
10.1101/2023.11.10.566489 — cell biology — Posted on 2023-11-10
3234 Immortalised murine R349P desmin knock-in myotubes exhibit a reduced proton leak and decreased ADP/ATP translocase levels in purified mitochondria
Berwanger, C.; Terres, D.; Pesta, D.; Eggers, B.; Marcus, K.; Wittig, I.; Wiesner, R. J.; Schroeder, R.; Clemen, C. S.
10.1101/2023.11.10.566522 — cell biology — Posted on 2023-11-10
3235 Fibroblast Nrf2 inhibits profibrotic transcription with Ddx54 and mitigates pathological fibrosis in the mouse heart and kidney
Hoshino, A.; Nishiji, T.; Ikemura, N.; Alcantara, M. C.; Higuchi, Y.; Uchio, Y.; Kirita, Y.; Taminishi, S.; Ozaki, Y.; Motooka, D.; Kobayashi, R.; Horii, T.; Hatada, I.; Matoba, S.
10.1101/2023.11.09.566496 — cell biology — Posted on 2023-11-10
3236 Discovery of the sEH Inhibitor Epoxykynin as Potent Kynurenine Pathway Modulator
Doetsch, L.; Davies, C.; Hennes, E.; Schoenfeld, J.; Kumar, A.; Da Cruz Lopes Guita, C.; Ehrler, J. H. M.; Hiesinger, K.; Thavam, S.; Janning, P.; Sievers, S.; Knapp, S.; Proschak, E.; Ziegler, S.; Waldmann, H.
10.1101/2023.11.09.566383 — cell biology — Posted on 2023-11-10
3237 DLG1 functions upstream of SDCCAG3 and IFT20 to control targeting of polycystin-2 to the primary cilium
Rezi, C. K.; Aslanyan, M.; Diwan, G. D.; Cheng, T.; Chamlali, M.; Junger, K.; Anvarian, Z.; Lorentzen, E.; Pauly, K. B.; Bahadori, Y.; Fernandes, E. F.; Qian, F.; Tosi, S.; Christensen, S. T.; Pedersen, S. F.; Stromgaard, K.; Russell, R. B.; Miner, J. H.; Mahjoub, M. R.; Boldt, K.; Roepman, R.; Pedersen, L. B.
10.1101/2023.11.10.566524 — cell biology — Posted on 2023-11-10
3238 A Proximal Sox2 Enhancer Cluster is Required for the Anterior Regional Identity of Neural Progenitors
Tobias, I. C.; Moorthy, S. D.; Shchuka, V. M.; Langroudi, L.; Gillespie, Z. E.; Duncan, A. G.; Tian, R.; Cherednychenko, M.; Gajewska, N. A.; Di Roberto, R. B.; Mitchell, J. A.
10.1101/2023.11.09.566464 — genetics — Posted on 2023-11-10
3240 Human pyramidal cell study in primary visual and associative temporal cortex reveals key morphological features responsible for areal specializations
Benavides Piccione, R.; Blazquez-Llorca, L.; Kastanauskaite, A.; Fernaud-Espinosa, I.; Gonzalez-Tapia, S.; DeFelipe, J.
10.1101/2023.11.10.566540 — neuroscience — Posted on 2023-11-10
3241 Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking
Patel, R.; Patarino, M.; Kim, K.; Pamintuan, R.; Taschbach, F.; Li, H.; Lee, C.; van Hoek, A.; Castro, R.; Cazares, C.; Miranda, R.; Jia, C.; Delahanty, J.; Batra, K.; Keyes, L.; Libster, A.; Wichmann, R. W.; Pereira, T.; Benna, M.; Tye, K. M.
10.1101/2023.11.09.566421 — neuroscience — Posted on 2023-11-10
3242 Hippocampal networks support reinforcement learning in partially observable environments
Pedamonti, D.; Mohinta, S.; Dimitrov, M.; Malagon-Vina, H.; Ciocchi, S.; Costa, R. P.
10.1101/2023.11.09.565503 — neuroscience — Posted on 2023-11-10
3243 m6A RNA modification of mHtt intron 1 regulates the generation of Htt1a in Huntington's Disease
Pupak, A.; Navarro, I. R.; Sathasivam, K.; Essmann, A.; Singh, A.; Del Toro, D.; Gines, S.; Bates, G. P.; Vang Orom, U. A.; Marti, E.; Brito, V.
10.1101/2023.11.10.566530 — neuroscience — Posted on 2023-11-10
3247 Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19
Narasimhan, H.; Cheon, I. S.; Qian, W.; Hu, S.; Parimon, T.; Zang, C.; Chen, P.; Sun, J.
10.1101/2023.09.13.557622 — immunology — Posted on 2023-11-10
3249 Subcortical correlates of consciousness with human single neuron recordings
Pereira, M.; Faivre, N.; Bernasconi, F.; Brandmeir, N.; Suffridge, J.; Tran, K.; Wang, S.; Finomore, V.; Konrad, P.; Rezai, A.; Blanke, O.
10.1101/2023.01.27.525684 — neuroscience — Posted on 2023-11-10
3250 Long-chain lipids facilitate insertion of large nanoparticles into membranes of small unilamellar vesicles
Marzouq, A.; Morgenstein, L.; Huang-Zhu, C.; Yudovich, S.; Atkins, A.; Grupi, A.; Van Lehn, R. C.; Weiss, S.
10.1101/2021.07.12.452073 — biophysics — Posted on 2023-11-10
3252 Emergence and spread of feline infectious peritonitis due to a highly pathogenic canine/feline recombinant coronavirus
Atippa, C.; Warr, A. S.; Epaminondas, D.; O'Shea, M.; Fletcher, S. L.; Malbon, A.; Lyraki, M.; Hammond, R.; Hardas, A.; Zanti, A.; Loukaidou, S.; Gentil, M.; Gunn-Moore, D.; Mazeri, S.; Tait-Burkard, C.
10.1101/2023.11.08.566182 — microbiology — Posted on 2023-11-10
3253 Increased plasma lipopolysaccharide-binding protein and altered inflammatory mediators in overweight women suggest a state of subclinical endotoxemia
Metz, C. N.; Xue, X.; Chatterjee, P. K.; Adelson, R.; Roth, J.; Brines, M.; Tracey, K. J.; Gregersen, P. K.; Pavlov, V.
10.1101/2023.05.18.540879 — immunology — Posted on 2023-11-10
3254 Homogenic endothelium-independent hematopoiesis ensures the abundance of erythrocytes and macrophages during zebrafish development.
Elsaid, R.; Mikdache, A.; Quintero Castillo, K.; Salloum, Y.; Diabangouaya, P.; Gros, G.; Feijoo, C.; Hernandez, P. P.
10.1101/2023.02.20.529211 — immunology — Posted on 2023-11-10
3256 Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
Wollman, A. J.; Syeda, A.; Howard, J.; Payne-Dwyer, A.; Leech, A.; Warecka, D.; Guy, C.; McGlynn, P.; Hawkins, M.; Leake, M. C.
10.1101/2021.02.22.432310 — biophysics — Posted on 2023-11-10
3257 Redox-active molecules in bacterial cultivation media produce photocurrent.
Shlosberg, Y.; Smith, M.; Nasseri, N. S.; Morin, E. J.; Limwongyut, J.; Moreland, A. S.; Bazan, G. C.; Carlini, A.
10.1101/2022.12.03.518941 — bioengineering — Posted on 2023-11-10
3259 Imaging with spatio-temporal modelling to characterize the dynamics of plant-pathogen lesions
Leclerc, M.; Jumel, S.; Hamelin, F. M.; Treilhaud, R.; Parisey, N.; Mammeri, Y.
10.1101/2022.01.13.476165 — ecology — Posted on 2023-11-10
3260 PINK1 regulated mitophagy is evident in skeletal muscles
Singh, F.; Wilhelm, L. P.; Prescott, A. R.; Ostacolo, K.; Zhao, J.-F.; Ogmundsdottir, M. H.; Ganley, I. G.
10.1101/2023.11.09.566402 — cell biology — Posted on 2023-11-10
3261 N-Terminus of Drosophila Melanogaster MSL1 Is Critical for Dosage Compensation
Babosha, V.; Klimenko, N.; Revel-Muroz, A.; Tikhonova, E.; Georgiev, P.; Maksimenko, O.
10.1101/2020.11.11.378323 — molecular biology — Posted on 2023-11-10
3262 Discovery and characterization of the first known biological lanthanide chelator
Zytnick, A. M.; Gutenthaler, S. M.; Aron, A. T.; Reitz, Z. L.; Phi, M. T.; Good, N. M.; Petras, D.; Daumann, L. J.; Martinez-Gomez, N. C.
10.1101/2022.01.19.476857 — microbiology — Posted on 2023-11-10
3267 Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing
Zhang, A.; Jin, L.; Yao, S.; Matsuyama, M.; Velthoven, C. v.; Sullivan, H.; Sun, N.; Kellis, M.; Tasic, B.; Wickersham, I. R.; Chen, X.
10.1101/2023.03.16.532873 — neuroscience — Posted on 2023-11-10
3268 The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Yu, D. S.; Outram, M. A.; Smith, A.; McCombe, C. L.; Khambalkar, P. B.; Rima, S. A.; Sun, X.; Ma, L.; Ericsson, D. J.; Jones, D. A.; Williams, S. J.
10.1101/2021.12.14.472499 — plant biology — Posted on 2023-11-10
3270 Pauperization of Emerin from nuclear envelope during chromatin bridge resolution drives prostate cancer cell migration and invasiveness
Nastaly, P.; Popeda, M.; Kowalski, K.; Wenta, T.; Beznoussenko, G.; Rychlowski, M.; Mironov, A.; Lavagnino, Z.; Barozzi, S.; Richert, J.; Bertolio, R.; Szade, J.; Miszewski, K.; Matuszewski, M.; Zaczek, A. J.; Braga, L.; Del Sal, G.; Bednarz-Knoll, N.; Maiuri, P.
10.1101/2023.11.06.565767 — cancer biology — Posted on 2023-11-10
3271 A mean-field theory for predicting single polymer collapse induced by neutral crowders
Chaboche, Q.; Campos-Villalobos, G.; Giunta, G.; Dijkstra, M.; Cosentino Lagomarsino, M.; Scolari, V. F.
10.1101/2023.07.12.548683 — biophysics — Posted on 2023-11-10
3276 Extracellular matrix imparts resilience to cancer spheroids
Dutt, T.; Langthasa, J.; U, M.; Mishra, S.; Bothra, S.; Vadaparty, A.; Sen, P.; Bhat, R.
10.1101/2022.02.09.479678 — biophysics — Posted on 2023-11-10
3280 Poisoning scientific knowledge using large language models
Yang, J.; Xu, H.; Mirzoyan, S.; Chen, T.; Liu, Z.; Ju, W.; Liu, L.; Zhang, M.; Wang, S.
10.1101/2023.11.06.565928 — bioinformatics — Posted on 2023-11-10
3281 A Multimodal Deep Learning Framework for Predicting PPI-Modulator Interactions
Sun, H.; Wang, J.; Wu, H.; Lin, S.; Chen, J.; Wei, J.; Lv, S.; Xiong, Y.; Wei, D.-Q.
10.1101/2023.08.03.551827 — bioinformatics — Posted on 2023-11-10
3283 Cholesterol regulates plasma membrane bending by prominin-family proteins
Bell, T. A.; Luce, B. E.; Hakim, P.; Dardari, H.; Ananda, V. Y.; Nguyen, T. H.; Monshizadeh, A.; Chao, L. H.
10.1101/2023.11.08.566258 — biochemistry — Posted on 2023-11-10
3284 Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15
Jain, R.; Geoghegan, G.; Davidson, J.; Nesbitt, D. J.; Abe, A.; Chao, X.; James, I.; Cavanagh, A. T.; Michorowska, S.; Verma, R.; Schueler, K. L.; Hinkoka-Galcheva, V.; Shishkova, E.; Ding, W.-X.; Coon, J. J.; Shayman, J.; Simcox, J.
10.1101/2023.11.03.565498 — biochemistry — Posted on 2023-11-10
3286 A preclinical model of THC edibles that produces high-dose cannabimimetic responses.
English, A.; Uittenbogaard, F.; Torrens, A.; Sarroza, D.; Slaven, A.; Piomelli, D.; Bruchas, M.; Stella, N.; Land, B. B.
10.1101/2022.11.23.517743 — animal behavior and cognition — Posted on 2023-11-10
3289 CAM evolution is associated with gene family expansion in an explosive bromeliad radiation
Groot Crego, C.; Hess, J.; Yardeni, G.; de la Harpe, M.; Priemer, C.; Beclin, F.; Cauz-Santos, L. A.; Saadain, S.; Temsch, E. M.; Weiss-Schneeweiss, H.; Barfuss, M. H. J.; Till, W.; Weckwerth, W.; Heyduk, K.; Lexer, C.; Paun, O.; Leroy, T.
10.1101/2023.02.01.526631 — evolutionary biology — Posted on 2023-11-10
3292 Extracellular DNA traps in a ctenophore demonstrate conserved immune cell behaviors in a non-bilaterian
Vandepas, L. E.; Stefani, C.; Domeier, P. P.; Traylor-Knowles, N.; Goetz, F. W.; Browne, W. E.; Lacy-Hulbert, A.
10.1101/2020.06.09.141010 — evolutionary biology — Posted on 2023-11-10
3295 Divergent ecological responses to typhoon disturbance revealed via landscape-scale acoustic monitoring
Ross, S. R. P.-J.; Friedman, N. R.; Dudley, K. L.; Yoshida, T.; Yoshimura, M.; Economo, E. P.; Armitage, D. W.; Donohue, I.
10.1101/2023.01.11.523682 — ecology — Posted on 2023-11-10
3298 A Mitochondrial Inside-Out Iron-Calcium Signal Identifies Drug Targets for Parkinsons Disease
Bharat, V.; Durairaj, A. S.; Vanhauwaert, R.; Li, L.; Muir, C. M.; Chandra, S.; Kwak, C. S.; Le Guen, Y.; Nandakishore, P.; Hsieh, C.-H.; Rensi, S. E.; Altman, R.; Greicius, M. D.; Feng, L.; Wang, X.
10.1101/2022.10.30.513580 — cell biology — Posted on 2023-11-10
3300 Distinct functions of the kinesin-9 family in mammalian motile cilia
Fang, C.; Pan, X.; Li, D.; Chen, Y.; Li, L.; Gao, Q.; Li, D.; Zhu, X.; Yan, X.
10.1101/2023.11.09.564704 — cell biology — Posted on 2023-11-10
3301 Global regulation via modulation of ribosome pausing by EttA
Ousalem, F.; Ngo, S.; Oiffer, T.; Omairi-Nasser, A.; Monlezun, L.; Boel, G.
10.1101/2023.10.17.562674 — microbiology — Posted on 2023-11-10
3304 Dissecting the properties of circulating IgG against Group A Streptococcus through a combined systems antigenomics-serology workflow
Chowdhury, S.; Gomez Toledo, A.; Hjortswang, E.; Sorrentino, J. T.; Lewis, N. E.; Bläckberg, A.; Ekström, S.; Izadi, A.; Nordenfelt, P.; Malmström, L.; Rasmussen, M.; Malmström, J.
10.1101/2023.11.07.565977 — immunology — Posted on 2023-11-10
3310 Unveiling dynamics behind Glioblastoma Multiforme single-cell data heterogeneity
Vieira Junior, M. G.; Cortes, A. M. d. A.; Carneiro, F. R. G.; Carels, N.; Silva, F. A. B. d.
10.1101/2023.04.25.538198 — systems biology — Posted on 2023-11-10
3312 FoxP3 recognizes microsatellites and bridges DNA through multimerization
Zhang, W.; Leng, F.; Wang, X.; Ramirez, R. N.; Park, J.; Benoist, C.; Hur, S.
10.1101/2023.07.12.548762 — biochemistry — Posted on 2023-11-10
3315 Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations
HINCKELMANN, M. V.; Dubos, A.; Artot, V.; Rudolf, G.; Nguyen, T. L.; Tilly, P.; Nalesso, V.; Muniz Moreno, M. d. M.; Birling, M.-C.; Godin, J.; Brault, V.; Herault, Y.
10.1101/2023.11.09.566424 — developmental biology — Posted on 2023-11-10
3317 Striatum supports fast learning but not memory recall
Reinhold, K.; Iadarola, M.; Tang, S.; Kuwamoto, W.; Sun, S.; Hakim, R.; Zimmer, J.; Wang, W.; Sabatini, B. L.
10.1101/2023.11.08.566333 — neuroscience — Posted on 2023-11-10
3319 Ecological interactions between host, commensal and pathogenic bacteria in models for the intestinal epithelium.
Nanlohy, N. M.; Johannesson, N.; Wijnands, L.; Arroyo, L.; de Wit, J.; den Hartog, G.; Wolthers, K. C.; Sridhar, A.; Fuentes, S.
10.1101/2023.11.09.565308 — microbiology — Posted on 2023-11-09
3320 Universal Digital High Resolution Melt for the detection of pulmonary mold infections
Goshia, T.; Aralar, A.; Wiederhold, N. P.; Jenks, J. D.; Mehta, S. R.; Sinha, M.; Karmakar, A.; Sharma, A.; Shrivastava, R.; Sun, H.; White, P. L.; Hoenigl, M.; Fraley, S. I.
10.1101/2023.11.09.566457 — microbiology — Posted on 2023-11-09
3322 Mechanistic basis of the dynamic response of TWIK1 ionic selectivity to pH
Chatelain, F. C.; Gilbert, N.; Bichet, D.; Jauch, A.; Feliciangeli, S.; LESAGE, F.; Bignucolo, O.
10.1101/2023.11.09.566352 — biochemistry — Posted on 2023-11-09
3323 Deuteration provides a general strategy to enhance azobenzene-based photopharmacology
Rossmann, K.; Gonzalez-Hernandez, A. J.; Bhuyan, R.; Boerjesson, K.; Levitz, J.; Broichhagen, J.
10.1101/2023.11.09.566420 — biochemistry — Posted on 2023-11-09
3326 Transglobal spread of an ecologically significant sea urchin parasite
Ritchie, I. T.; Vilanova-Cuevas, B.; Altera, A.; Cornfield, K.; Evans, C.; Evans, J. S.; Hopson-Fernandes, M.; Kellogg, C. A.; Looker, E.; Taylor, O.; Hewson, I.; Breitbart, M.
10.1101/2023.11.08.566283 — ecology — Posted on 2023-11-09
3327 NaP-TRAP, a novel massively parallel reporter assay to quantify translation control.
Strayer, E. C.; Krishna, S.; Lee, H.; Vejnar, C.; Beaudoin, J.-D.; Giraldez, A. J.
10.1101/2023.11.09.566434 — molecular biology — Posted on 2023-11-09
3328 Signal Transduction in an Enzymatic Photoreceptor Revealed by Cryo-Electron Microscopy
Malla, T. N.; Hernandez, C.; Menendez, D.; Bizhga, D.; Mendez, J. H.; Muniyappan, S.; Schwander, P.; Stojkovic, E. A.; Schmidt, M.
10.1101/2023.11.08.566274 — molecular biology — Posted on 2023-11-09
3329 Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing
Heruye, S.; Myslinski, J.; Zeng, C.; Zollman, A.; Makino, S.; Nanamatsu, A.; Mir, Q.; Janga, S. C.; Doud, E. H.; Eadon, M. T.; Maier, B.; Hamada, M.; Tran, T. M.; Dagher, P.; Hato, T.
10.1101/2023.11.09.566426 — molecular biology — Posted on 2023-11-09
3330 Short internal open reading frames regulate the translation of N-terminally truncated proteoforms
Fettig, R.; Gonda, Z.; Walter, N.; Sallmann, P.; Thanisch, C.; Winter, M.; Bauer, S.; Zhang, L.; Linden, G.; Litfin, M.; Etard, C.; Armant, O.; Vazquez, O.; Kassel, O.
10.1101/2023.11.09.566418 — molecular biology — Posted on 2023-11-09
3331 Efficient workflow for validating homology-independent targeted integration-mediated gene insertion in rod photoreceptor cells to treat dominant-negative mutations causing retinitis pigmentosa
Onishi, A.; Tsunekawa, Y.; Mandai, M.; Ishimaru, A.; Ohigashi, Y.; Sho, J.; Yasuda, K.; Suzuki, K.; Izpisua Belmonte, J. C.; Matsuzaki, F.; Takahashi, M.
10.1101/2023.11.08.566127 — molecular biology — Posted on 2023-11-09
3332 Finding needles in haystacks: identification of novel conserved PETase enzymes in Streptomyces
Verschoor, J.-A.; Croese, M.; Lakemeier, S.; Mugge, A.; Burgers, C.; Innocenti, P.; Willemse, J.; Crooijmans, M.; van Wezel, G.; Ram, A.; de Winde, J.
10.1101/2023.11.08.566248 — microbiology — Posted on 2023-11-09
3335 Design of a symmetry-broken tetrahedral protein cage by a method of internal steric occlusion
Gladkov, N.; Scott, E. A.; Meador, K.; Lee, E. J.; Laganowsky, A. D.; Yeates, T. O.; Castells-Graells, R.
10.1101/2023.11.08.566319 — biochemistry — Posted on 2023-11-09
3339 An optimized protocol for the creation of constructs expressing sodium channel subunits to be used in functional studies of genetic epilepsies
-Samanamud, S. L.; do canto, A. M.; Torres, F. R.; Gonsales, M. C.; Godoi, A. B.; da Rosa, D. C.; Vieira, A. S.; -Cendes, I. L.
10.1101/2023.11.08.565006 — molecular biology — Posted on 2023-11-09
3340 MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
Kim, H.; Lebeau, B.; Papadopoli, D.; Jovanovic, P.; Russo, M.; Avizonis, D.; Morita, M.; Afzali, F.; Ursini-Siegel, J.; Postovit, L.-M.; Witcher, M.; Topisirovic, I.
10.1101/2023.11.07.566067 — molecular biology — Posted on 2023-11-09
3341 Emergence and spread of feline infection peritonitis due to a highly pathogenic canine/feline recombinant coronavirus
Atippa, C.; Warr, A. S.; Epaminondas, D.; O'Shea, M.; Fletcher, S. L.; Malbon, A.; Lyraki, M.; Hammond, R.; Hardas, A.; Zanti, A.; Loukaidou, S.; Gentil, M.; Gunn-Moore, D.; Mazeri, S.; Tait-Burkard, C.
10.1101/2023.11.08.566182 — microbiology — Posted on 2023-11-09
3342 Global distribution and diversity of marine Parmales
Ban, H.; Endo, H.; The EukBank Team, ; Kuwata, A.; Ogata, H.
10.1101/2023.11.09.566328 — microbiology — Posted on 2023-11-09
3343 The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription
Aiken, C.; Jennings, J.; Bracey, H.; Nguyen, D. T.; Dasgupta, R.; Rivera, A. V.; Sluis-Cremer, N.; Shi, J.
10.1101/2023.11.08.566350 — microbiology — Posted on 2023-11-09
3346 Genomic tailoring of autogenous poultry vaccines to reduce Campylobacter from farm to fork
Calland, J. K.; Pesonen, M. E.; Mehat, J.; Pascoe, B.; Haydon, D. J.; Lourenco, J.; Mourkas, E.; Hitchings, M. D.; LaRagione, R. M.; Hammond, P.; Wallis, T. S.; Corander, J.; Sheppard, S. K.
10.1101/2023.11.09.566360 — microbiology — Posted on 2023-11-09
3348 Dynamics of Trypanosoma cruzi infection in hamsters and novel association with progressive motor dysfunction
Langston, H.; Francisco, A. F.; Doidge, C.; Roberts, C. H.; Khan, A. A.; Jayawardhana, S.; Taylor, M. C.; Kelly, J. M.; Lewis, M. D.
10.1101/2023.11.09.566419 — microbiology — Posted on 2023-11-09
3350 Are Escherichia coli causing recurrent cystitis just ordinary Uropathogenic E. coli (UPEC) strains?
Vautrin, N.; Dahyot, S.; Leoz, M.; Caron, F.; Grand, M.; Feldmann, A.; Gravey, F.; Legris, S.; Ribet, D.; Alexandre, K.; Pestel-Caron, M.
10.1101/2023.11.08.566351 — microbiology — Posted on 2023-11-09
3353 Phenotypic heterogeneity drives phage-bacteria coevolution in the intestinal tract
Wenner, N.; Bertola, A.; Larsson, L.; Rocker, A.; Bekele, N. A.; Sauerbeck, C.; Rocha, L. F. L.; Druelle, V.; Harms, A.; Diard, M.
10.1101/2023.11.08.566301 — microbiology — Posted on 2023-11-09
3354 Robust detection of SARS-CoV-2 exposure in population using T-cell repertoire profiling
Vlasova, E. K.; Nekrasova, A. I.; Komkov, A. Y.; Izraelson, M.; Snigir, E. A.; Mitrofanov, S. I.; Yudin, V. S.; Makarov, V. V.; Kesnikov, A. A.; Kirienko, D.; Pivnyuk, A.; Shelyakin, P. V.; Mamedov, I. Z.; Rebrikov, D. V.; Chudakov, D. M.; Yudin, S. M.; Skvortsova, V. I.; Britanova, O.; Shugay, M. A.
10.1101/2023.11.08.566227 — immunology — Posted on 2023-11-09
3360 Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia
Nikhila, L.; Surya, S.; Najeeb, S. H.; Binumon, T. M.; Gupta, A.; Gopalakrishnan, S.; Panicker, S. P.
10.1101/2023.11.07.566136 — cell biology — Posted on 2023-11-09
3361 Mesenchymal Stromal Cells regulate human Hematopoietic Stem Cell survival and regeneration via cAMP/PKA pathway
Milyavsky, M.; MUDDINENI, S. S. N. A.; Katz-Even, C.; Zipin-Roitman, A.; Weizman, E.; Nagler, A.; Raz, Y.; Beider, K.
10.1101/2023.11.09.566361 — cell biology — Posted on 2023-11-09
3363 Vault particles are common contaminants of extracellular vesicle preparations
Liu, X.; Nizamudeen, Z.; Hill, C. J.; Parmenter, C.; Arkill, K. P.; Lambert, D. W.; Hunt, S.
10.1101/2023.11.09.566362 — cell biology — Posted on 2023-11-09
3368 Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease
Srivastava, S. P.; Zhou, H.; Shenoi, R.; Morris, M.; Goedeke, L.; Rajendran, B. K.; Setia, O.; Aryal, B.; Kanasaki, K.; Koya, D.; Dardik, A.; Bell, T.; Fernandez-Hernando, C.; Shulman, G.; Goodwin, J. E.
10.1101/2023.11.08.565844 — cell biology — Posted on 2023-11-09
3369 Distinct functions of the kinesin-9 family in mammalian motile cilia
Fang, C.; Pan, X.; Li, D.; Chen, Y.; Li, L.; Gao, Q.; Li, D.; Zhu, X.; Yan, X.
10.1101/2023.11.09.564704 — cell biology — Posted on 2023-11-09
3371 PINK1 regulated basal mitophagy is evident in skeletal muscles
Singh, F.; Wilhelm, L. P.; Prescott, A. R.; Ostacolo, K.; Zhao, J.-F.; Ogmundsdottir, M. H.; Ganley, I. G.
10.1101/2023.11.09.566402 — cell biology — Posted on 2023-11-09
3374 The entropic heart: Tracking the psychedelic state via heart rate dynamics
Rosas, F. E.; Mediano, P. A. M.; Timmermann, C.; Luppi, A. I.; Candia-Rivera, D.; Abbasi-Asl, R.; Gazzaley, A.; Kringelbach, M. L.; Muthukumaraswamy, S. D.; Bor, D.; Garfinkel, S.; Carhart-Harris, R.
10.1101/2023.11.07.566008 — physiology — Posted on 2023-11-09
3376 Maternal H3.3-Mediated Paternal Genome Reprogramming Contributes to Minor Zygotic Genome Activation
Zhang, J.; Li, X.; Cui, H.; Xiao, S.; Song, E.; Zong, M.; Ling, S.; Rosenwaks, Z.; Gao, S.; Liu, X.; Kong, Q.; Wen, D.
10.1101/2023.11.07.566007 — genetics — Posted on 2023-11-09
3378 Precise age estimation in clonal species using a somatic genetic clock
Yu, L.; Renton, J.; Burian, A.; Khachaturyan, M.; Kotta, J.; Stachowicz, J. C.; DuBois, K.; Baums, I. B.; Werner, B.; Reusch, T. B. H.
10.1101/2023.11.07.566010 — evolutionary biology — Posted on 2023-11-09
3389 Dissecting the properties of circulating IgG against Group A Streptococcus through a combined systems antigenomics-serology workflow
Malmstrom, J.; Chowdhury, S.; Gomez Toledo, A.; Hjortswang, E.; Sorrentino, J. T.; Lewis, N. E.; Blackberg, A.; Ekstrom, S.; Izadi, A.; Nordenfelt, P.; Malmstrom, L.; Rasmussen, M.
10.1101/2023.11.07.565977 — immunology — Posted on 2023-11-09
3390 Anti-inflammatory immunomodulation for the treatment of Congenital Diaphragmatic Hernia
Vallejo-Cremade, M.; Merino, J.; Carmona, R.; Cordoba, L.; Salvador, B.; Martinez, L.; Tovar, J. A.; Llamas, M. A.; Munoz-Chapuli, R.; Fresno, M.
10.1101/2023.11.07.565809 — immunology — Posted on 2023-11-09
3394 MYC amplifies mitotic perturbations elicited by LXY18 to enable synthetic lethality
Yang, D.; Kalashova, J.; Yang, C.; Long, Y.; Li, H.; Zhang, S.; Zhang, T.; Yu, D.; Liu, X.; Lv, G.; Choudhry, N.; Liu, H.; Shi, Q.
10.1101/2023.11.07.565938 — cancer biology — Posted on 2023-11-09
3395 A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens
Gegner, H.; Naake, T.; Aljakouch, K.; Dugourd, A.; Kliewer, G.; Mueller, T.; Schilling, D.; Schneider, M. A.; Kunze, N.; Gruenewald, T. G. P.; Hell, R.; Saez-Rodriguez, J.; Huber, W.; Poschet, G.; Krijgsveld, J.
10.1101/2023.11.07.561857 — cancer biology — Posted on 2023-11-09
3397 A new paradigm for biological sequence retrieval inspired by natural language processing and database research
Rousseau, A.-J.; Lemal, S.; Korovin, Y.; Triantopoulos, G.; Brands, I.; Biemans, M.; Van Hyfte, D.; Valkenborg, D.
10.1101/2023.11.07.565984 — bioinformatics — Posted on 2023-11-09
3398 OmniReprodubileCellAnalysis: a comprehensive toolbox for the analysis of cellular biology data.
Tortarolo, D.; Pernice, S.; Clapero, F.; Valdembri, D.; Serini, G.; Riccardo, F.; Tarone, L.; Bena, C. E.; Bosio, C.; Contaldo, S. G.; Beccuti, M.; Pennisi, M.; Cordero, F.
10.1101/2023.11.07.565961 — bioinformatics — Posted on 2023-11-09
3400 Statistical framework for calling allelic imbalance in high-throughput sequencing data
Andrey Buyan, A.; Meshcheryakov, G.; Safronov, V.; Abramov, S.; Boytsov, A.; Nozdrin, V.; Baulin, E. F.; Kolmykov, S.; Vierstra, J.; Kolpakov, F.; Makeev, V. J.; Kulakovskiy, I. V.
10.1101/2023.11.07.565968 — bioinformatics — Posted on 2023-11-09
3402 Multi-modal microvascular cerebral blood flow velocity mapping with 14T single-vessel MRI and optical microscopy in the mouse brain
Miller, D. R.; Zhou, X. A.; Liang, S.; Xie, Z.; Fu, B.; Shin, P.; Pian, Q.; Jiang, Y.; Liu, A.; Tang, J.; Devor, A.; Yu, X.; Sakadzic, S.
10.1101/2023.11.07.566001 — bioengineering — Posted on 2023-11-09
3404 Emerging role of mesenchymal stem cell-derived extracellular vesicles to ameliorate hippocampal NLRP3 inflammation induced by binge-like ethanol treatment in adolescence
Mellado, S.; Morillo-Bargues, M. J.; Perpina-Clerigues, C.; Touahri, N.; Garcia-Garcia, F.; Moreno-Manzano, V.; Guerri, C.; Pascual, M.
10.1101/2023.11.07.565776 — neuroscience — Posted on 2023-11-09
3408 Model-based inference of a plant-specific dual role for HOPS in regulating guard cell vacuole fusion
Hodgens, C.; Flaherty, D.; Pullen, A.-M.; Khan, I.; English, N. J.; Gillan, L.; Rojas-Pierce, M.; Akpa, B.
10.1101/2023.11.07.565947 — systems biology — Posted on 2023-11-09
3409 Early antigen receptor signaling in natural killer cells alters STAT4-dependent fate decisions via epigenetic remodeling
Grassmann, S.; Santosa, E. K.; Mujal, A. M.; Kim, H.; Fan, S. X.; Owyong, M.; Lau, C. M.; Sun, J. C.
10.1101/2023.11.07.565992 — immunology — Posted on 2023-11-09
3413 Light-evoked deformations in rod photoreceptors, pigment epithelium and subretinal space revealed by prolonged and multilayered optoretinography
Tan, B.; Li, H.; Zhuo, Y.; Han, L.; Mupparapu, R.; Nanni, D.; Barathi, V. A.; Palanker, D.; Schmetterer, L.; Ling, T.
10.1101/2023.03.03.530926 — bioengineering — Posted on 2023-11-09
3415 Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells
Yao, Y.; Lou, X.; Jin, L.; Li, J.; Liu, J.; Chen, Y.; Cheng, S.; Zhao, T.; Ke, S.; Zhang, L.; Zhang, P.; Xu, Y.; He, L.; Li, H.
10.1101/2023.08.03.551799 — cell biology — Posted on 2023-11-09
3418 A combined DTI-fMRI approach for optimizing the delineation of posteromedial vs. anterolateral entorhinal cortex
Syversen, I. F.; Reznik, D.; Witter, M. P.; Kobro-Flatmoen, A.; Navarro Schroder, T.; Doeller, C. F.
10.1101/2022.12.23.520976 — neuroscience — Posted on 2023-11-09
3420 Dynamic simulations of feeding and respiration of the early Cambrian periderm-bearing cnidarian polyps
Zhang, Y.; Wang, X.; Han, J.; Xiao, J.; Yong, Y.; Yu, C.; Yue, N.; Sun, J.; He, K.; Hao, W.; Zhang, T.; Wang, B.; Wang, D.; Yang, X.
10.1101/2023.07.28.550931 — evolutionary biology — Posted on 2023-11-09
3422 The neuronal homeobox transcription factor HMX3 is a crucial vulnerability factor in MECOM-negative KMT2A::MLLT3 acute myelomonocytic leukemia
Arza-Apalategi, S.; Heuts, B. M. H.; Bergevoet, S. M.; Meering, R.; Gilissen, D.; Jansen, P. W. T. C.; Krippner-Heidenreich, A.; Valk, P. J. M.; Vermeulen, M.; Heidenreich, O.; Haferlach, T.; Jansen, J. H.; Martens, J. H. A.; van der Reijden, B. A.
10.1101/2023.11.07.565950 — cancer biology — Posted on 2023-11-09
3423 Distal regulatory sequences contribute to diversity in brain oxytocin receptor expression patterns and social behavior
Zhang, Q.; Nagai, L. A. E.; Tsukamoto, M.; Kandasamy, L. C.; Inoue, K.; Pires, M. F.; Shin, M.; Nagasawa, Y.; Sambuu, T.; Ogawa, S.; Nakai, K.; Itohara, S.; Young, L. J.
10.1101/2022.12.01.518660 — neuroscience — Posted on 2023-11-09
3425 In situ architecture of Opa1-dependent mitochondrial cristae remodeling
Fry, M. Y.; Navarro, P. P.; Hakim, P.; Ananda, V. Y.; Qin, X.; Landoni, J. C.; Rath, S.; Inde, Z.; Lugo, C. M.; Luce, B. E.; Ge, Y.; McDonald, J. L.; Ali, I.; Ha, L. L.; Kleinstiver, B. P.; Chan, D. C.; Sarosiek, K.; Chao, L. H.
10.1101/2023.01.16.524176 — biophysics — Posted on 2023-11-09
3427 Apis mellifera filamentous virus from a honey bee gut microbiome survey in Hungary
Papp, M.; Toth, A. G.; Bekesi, L.; Farkas, R.; Makrai, L.; Maroti, G.; Solymosi, N.
10.1101/2023.07.17.549372 — bioinformatics — Posted on 2023-11-09
3430 Neurophysiological trajectories in Alzheimer's disease progression
Kudo, K.; Ranasinghe, K. G.; Morise, H.; Syed, F.; Sekihara, K.; Rankin, K. P.; Miller, B. L.; Kramer, J.; Rabinovici, G.; Vossel, K.; Kirsch, H. E.; Nagarajan, S.
10.1101/2023.05.18.541379 — neuroscience — Posted on 2023-11-09
3431 Co-transcriptional production of programmable RNA condensates and synthetic organelles
Fabrini, G.; Nuccio, S. P.; Stewart, J. M.; Li, S.; Tang, A.; Rothemund, P. W. K.; Franco, E.; Di Antonio, M.; Di Michele, L.
10.1101/2023.10.06.561174 — synthetic biology — Posted on 2023-11-09
3436 Anoctamin-1 is induced by TGF-beta and contributes to lung myofibroblast differentiation
Reed, E. B.; Orbeta, S.; Miao, B. A.; Sitikov, A.; Chen, B.; Levitan, I.; Solway, J.; Mutlu, G. M.; Fang, Y.; Mongin, A. A.; Dulin, N. O.
10.1101/2023.06.07.544093 — cell biology — Posted on 2023-11-09
3437 qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes.
Philip, R.; Sharma, A.; Matellan, L.; Erpf, A. C.; Hsu, W.-H.; Tkach, J. M.; Wyatt, H. D. M.; Pelletier, L.
10.1101/2023.11.01.565029 — molecular biology — Posted on 2023-11-09
3438 Exploratory Correlation of the Human Structural Connectome with Non-MRI Variables in Alzheimer's Disease
Aganj, I.; Mora, J.; Frau-Pascual, A.; Fischl, B. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.30.547308 — neuroscience — Posted on 2023-11-09
3440 A vasopressin circuit that modulates sex-specific social interest and anxiety-like behavior in mice
Rigney, N.; Campos-Lira, E.; Kirchner, M. K.; Wei, W.; Belkasim, S.; Beaumont, R.; Singh, S.; Stern, J. E.; de Vries, G. J.; Petrulis, A.
10.1101/2023.11.06.564847 — neuroscience — Posted on 2023-11-09
3444 Disuse-driven plasticity in the human thalamus and putamen
Chauvin, R. J.; Newbold, D. J.; Nielsen, A. N.; Miller, R. L.; Krimmel, S. R.; Metoki, A.; Wang, A.; Van, A. N.; Montez, D. F.; Suljic, V.; Baden, N. J.; Ramirez-Perez, N.; Scheidter, K. M.; Monk, J. S.; Whiting, F. I.; Adeyemo, B.; Kay, B. P.; Laumann, T. O.; Gordon, E. M.; Dosenbach, N. U. F.
10.1101/2023.11.07.566031 — neuroscience — Posted on 2023-11-08
3450 NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation
Yu, T.; Hou, D.; Zhao, J.; Lu, X.; Greentree, W. K.; Zhao, Q.; Conde, D.-G.; Linder, M. E.; Lin, H.
10.1101/2023.11.07.566005 — immunology — Posted on 2023-11-08
3453 Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns
Law, R. C.; O'Keeffe, S.; Nurwono, G.; Ki, R.; Lakhani, A.; Lai, P.-K.; Park, J. O.
10.1101/2023.11.06.565907 — systems biology — Posted on 2023-11-08
3454 Glucose-6-phosphate dehydrogenase deficiency accelerates pancreatic acinar-to-ductal metaplasia
Radyk, M. D.; Nelson, B. S.; Halbrook, C. J.; Wood, A.; Lavoie, B.; Salvatore, L.; Corfas, G.; Colacino, J.; Shah, Y. M.; Crawford, H. C.; Lyssiotis, C. A.
10.1101/2023.11.06.565895 — cancer biology — Posted on 2023-11-08
3456 Poisoning medical knowledge using large language models
Yang, J.; Xu, H.; Mirzoyan, S.; Chen, T.; Liu, Z.; Ju, W.; Liu, L.; Zhang, M.; Wang, S.
10.1101/2023.11.06.565928 — bioinformatics — Posted on 2023-11-08
3457 On the limits of 16S rRNA gene-based metagenome prediction and functional profiling
Matchado, M. S.; Ruhlemann, M. C.; Reimeiter, S.; Kacprowski, T.; Frost, F.; Haller, D.; Baumbach, J.; List, M.
10.1101/2023.11.07.564315 — bioinformatics — Posted on 2023-11-08
3458 Topical siRNA therapy of diabetic-like wound healing
Neuhoferova, E.; Kindermann, M.; Buzgo, M.; Vocetkova, K.; Panek, D.; Cigler, P.; Benson, V.
10.1101/2023.11.06.565704 — bioengineering — Posted on 2023-11-08
3459 Protein thiol alterations drive aberrant phase separation in aging
Vignane, T.; Hugo, M.; Hoffmann, C.; Katsouda, A.; Petric, J.; Wang, H.; Miler, M.; Comas, F.; Petrovic, D.; Chen, S.; Miljkovic, J. L.; Morris, J. L.; Chowdury, S. R.; Prudent, J.; Polovic, N.; Murphy, M.; Papapetropoulos, A.; Milovanovic, D.; Filipovic, M.
10.1101/2023.11.07.566021 — biochemistry — Posted on 2023-11-08
3464 Sex chromosome turnover in hybridizing stickleback lineages
Yi, X.; Wang, D.; Reid, K.; Feng, X.; Löytynoja, A.; Merilä, J.
10.1101/2023.11.06.565909 — evolutionary biology — Posted on 2023-11-08
3465 Bacterial Diversity and Chemical Ecology of Natural Product-Producing Bacteria from Great Salt Lake Sediment
Bring Horvath, E. R.; Brazelton, W. J.; Kim, M. C.; Cullum, R.; Mulvey, M. A.; Fenical, W.; Winter, J. M.
10.1101/2023.11.07.565188 — ecology — Posted on 2023-11-08
3467 Insectivorous birds and bats outperform ants in the top-down regulation of arthropods across strata of a Japanese temperate forest
Sivault, E.; Kollross, J.; Jorge, L. R.; Finnie, S.; Mendez, D. D.; Garzon, S. F.; Maraia, H.; Lenc, J.; Libra, M.; Murakami, M.; Nakaji, T.; Nakamura, M.; Sreekar, R.; Sam, L.; Abe, T.; Weiss, M.; Sam, K.
10.1101/2023.11.07.565745 — ecology — Posted on 2023-11-08
3469 Comprehensive IsomiR sequencing profile of human pancreatic islets and EndoC-βH1 beta-cells
Auddino, S.; Aiello, E.; Toniolli, M.; Grieco, G. E.; Fignani, D.; Licata, G.; Bruttini, M.; Mori, A.; Berteramo, A. F.; Pedace, E.; Nigi, L.; Formichi, C.; Quero, G.; Tondolo, V.; Di Giuseppe, G.; Soldovieri, L.; Mari, A.; Giaccari, A.; Mezza, T.; Dotta, F.; Sebastiani, G.
10.1101/2023.11.08.566223 — molecular biology — Posted on 2023-11-08
3470 Enteric Populations of Escherichia coli are Likely to be Resistant to Phages Due to O Antigen Production
Berryhill, B. A.; Burke, K. B.; Fontaine, J.; Brink, C. E.; Harvill, M. G.; Goldberg, D. A.; Konstantinidis, K. T.; Levin, B. R.; Woodworth, M. H.
10.1101/2023.11.08.566299 — microbiology — Posted on 2023-11-08
3471 A BCG Skin Challenge Model for Assessing TB Vaccines
Krishnan, N.; Priestman, M.; Uhia, I.; Charitakis, N. C.; Glegola-Madejska, I. T.; Baer, T. M.; Tranberg, A.; Faraj, A.; Simonsson, U. S.; Robertson, B. D.
10.1101/2023.11.08.566238 — microbiology — Posted on 2023-11-08
3473 An acidophilic fungus is integral to prey digestion in a carnivorous plant
Sun, P.-F.; Lu, M. R.; Liu, Y.-C.; Lin, Y.-f.; Hoh, D. Z.; Ke, H.-M.; Wang, I.-F.; Lu, M.-Y. J.; Kirschner, R.; Lin, Y.-C. J.; Chen, Y.-L.; Tsai, I. J.
10.1101/2023.11.07.566145 — microbiology — Posted on 2023-11-08
3475 Arousal as a universal embedding for spatiotemporal brain dynamics
Raut, R. V.; Rosenthal, Z. P.; Wang, X.; Miao, H.; Zhang, Z.; Lee, J.-M.; Raichle, M. E.; Bauer, A. Q.; Brunton, S. L.; Brunton, B. W.; Kutz, J. N.
10.1101/2023.11.06.565918 — neuroscience — Posted on 2023-11-08
3482 Cholesterol regulates plasma membrane bending by prominin-family proteins
Bell, T. A.; Luce, B. E.; Hakim, P.; Dardari, H.; Ananda, V. Y.; Nguyen, T. H.; Monshizedeh, A.; Chao, L. H.
10.1101/2023.11.08.566258 — biochemistry — Posted on 2023-11-08
3483 Conformational diversity in class C GPCR positive allosteric modulation
Cannone, G.; Berto, L.; Malhaire, F.; Ferguson, G.; Fouillen, A.; Balor, S.; Font-Ingles, J.; Llebaria, A.; GOUDET, C.; Kotecha, A.; Kutti, V. R.; Lebon, G.
10.1101/2023.11.07.565819 — biochemistry — Posted on 2023-11-08
3485 Acetyl-CoA carboxylase inhibition increases RPE cell fatty acid oxidation and limits apolipoprotein efflux
Hass, D. T.; Pandey, K.; Engel, A. L.; Horton, N.; Robbings, B. M.; Lim, R.; Sadilek, M.; Zhang, Q.; Autterson, G. A.; Miller, J. M.; Chao, J. R.; Hurley, J. B.
10.1101/2023.11.07.566117 — biochemistry — Posted on 2023-11-08
3486 Daily time constraints limit behavioural capacity to cope with thermally increased metabolic demands
Byrnes, E. E.; Adam, T.; Feldmann, C. C.; Kaplinskaya, L.; Sticker, K.; Fredebeul, R. J.; Lear, K. O.; Morgan, D. L.; Beatty, S. J.; Langrock, R.; Gleiss, A. C.
10.1101/2023.11.06.565854 — ecology — Posted on 2023-11-08
3488 ChatGPT usage in the Reactome curation process
Tiwari, K. K.; Matthews, L.; May, B.; Shamovsky, V.; Orlic-Milacic, M.; Rothfels, K.; Ragueneau, E.; Gong, C.; Stephan, R.; Li, N.; Wu, G.; Stein, L. D.; D'eustachio, P.; Hermjakob, H.
10.1101/2023.11.08.566195 — molecular biology — Posted on 2023-11-08
3490 Nanoscale cellular organization of viral RNA and proteins in SARS-CoV-2 replication organelles
Andronov, L.; Han, M.; Zhu, Y.; Roy, A. R.; Barentine, A. E. S.; Garhyan, J.; Qi, L. S.; Moerner, W. E.
10.1101/2023.11.07.566110 — microbiology — Posted on 2023-11-08
3494 SPATEs promote the survival of Shigella to the plasma complement system upon hemorrhage and bacteremia
Debande, L.; Sabbah, A.; Kuhn, L.; Ngondo, P.; Andre, A. C.; Roche, B.; Laborde, M.; Cantalapiedra-Mateo, M.-V.; Thahouly, T.; Milinski, A.; Bianchetti, L.; Allmang-Cura, C.; Frugier, M.; Marteyn, B. S.
10.1101/2023.11.08.565994 — microbiology — Posted on 2023-11-08
3495 Supervised White Matter Bundle Segmentation in Glioma Patients with Transfer Learning
Riccardi, C.; Ghezzi, S.; Amorosino, G.; Zigiotto, L.; Sarubbo, S.; Jovicich, J.; Avesani, P.
10.1101/2023.07.31.551318 — neuroscience — Posted on 2023-11-08
3497 Shaping human gut community assembly and butyrate production by controlling the arginine dihydrolase pathway
Liu, Y.; Cheng, Y.-Y.; Zhou, Z.; Vivas, E. I.; Warren, M. F.; Rey, F. E.; Anantharaman, K.; Venturelli, O. S.
10.1101/2023.01.10.523442 — systems biology — Posted on 2023-11-08
3499 A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes
Ellis, N. A.; Myers, K. S.; Tung, J.; Davidson Ward, A.; Johnston, K.; Bonnington, K. E.; Donohue, T. J.; Machner, M. P.
10.1101/2023.02.03.527066 — genetics — Posted on 2023-11-08
3503 Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
Martin-Flores, N.; Podpolny, M.; McLeod, F.; Workman, I.; Crawford, K.; Ivanov, D.; Leonenko, G.; Escott-Price, V.; Salinas, P. C.
10.1101/2022.06.16.495307 — neuroscience — Posted on 2023-11-08
3504 High-resolution glucose tracing and in situ imaging reveals regulated lactate production in human pancreatic β cells
Cuozzo, F.; Viloria, K.; Shilleh, A. H.; Nasteska, D.; Frazer-Morris, C.; Jiao, Z.; Boufersaoui, A.; Marzullo, B.; Smith, H. R.; Bonner, C.; Kerr-Conte, J.; Pattou, F.; Nano, R.; Piemonti, L.; Johnson, P. R.; Spiers, R.; Roberts, J.; Lavery, G. G.; Clark, A.; Ceresa, C. D.; Hodson, L.; Davies, A. P.; Rutter, G.; Oshima, M.; Scharfmann, R.; Merrins, M. J.; Akerman, I.; Tennant, D. A.; Ludwig, C.; Hodson, D. J.
10.1101/2022.12.21.521364 — physiology — Posted on 2023-11-08
3505 Synthetic Notch Activation Patterns in a Proliferating Tissue
Dawson, J.; Bryant, A.; Jordan, T.; Bhikot, S.; Macon, S.; Walton, B.; Ajamu-Johnson, A.; Langridge, P. D.; Malmi-Kakkada, A. N.
10.1101/2023.07.12.548752 — biophysics — Posted on 2023-11-08
3507 Sources of gene expression variation in a globally diverse human cohort
Taylor, D. J.; Chhetri, S. B.; Biddanda, A.; Tassia, M. G.; Battle, A.; McCoy, R. C.
10.1101/2023.11.04.565639 — genomics — Posted on 2023-11-08
3509 Identification of a convergent spinal neuron population that encodes itch
Sheahan, T. D.; Warwick, C. A.; Cui, A. Y.; Baranger, D. A.; Perry, V. J.; Smith, K. M.; Manalo, A. P.; Nguyen, E. K.; Koerber, H. R.; Ross, S. E.
10.1101/2023.09.29.560205 — neuroscience — Posted on 2023-11-08
3511 Grubraw, a chemogenetic mitochondrial activator, reveals new mechanisms underlying the Warburg effect
Potekhina, E. S.; Bass, D. Y.; Ivanenko, A. V.; Moshchenko, A. A.; Korzhenevskiy, D. A.; Shevchenko, E.; Karnaeva, A. E.; Zakirova, N. F.; Ivanov, A. V.; Shimolina, L. E.; Shirmanova, M. V.; Lyang, O. V.; Patsap, O. I.; Kudryashova, O. M.; Gazizova, G. R.; Shagimardanova, E. I.; Gusev, O. A.; Bogeski, I.; Nesterenko, A. M.; Belousov, V.
10.1101/2023.04.18.537329 — cancer biology — Posted on 2023-11-08
3512 Molecular quantitative trait loci in reproductive tissues impact male fertility in cattle
Mapel, X. M.; Kadri, N. K.; Leonard, A. S.; He, Q.; Lloret-Villas, A.; Bhati, M.; Hiltpold, M.; Pausch, H.
10.1101/2023.06.29.547066 — genomics — Posted on 2023-11-08
3516 Development and utilization of new O2-independent bioreporters
Agranier, E.; Cretin, P.; Joublin-Delavat, A.; Veillard, L.; Touahri, K.; Delavat, F.
10.1101/2023.11.07.566077 — molecular biology — Posted on 2023-11-08
3520 Proteomic assay for rapid characterization of Staphylococcus aureus antimicrobial resistance directly from blood cultures
Deforet, F.; Carriere, R.; L'Aour Dufour, P.; Prat, R.; Desbiolles, C.; Cottin, N.; Reuzeau, A.; Dauwalder, O.; Dupieux-Chabert, C.; Tristan, A.; Cecchini, T.; Lemoine, J.; Vandenesch, F.
10.1101/2023.11.06.565783 — microbiology — Posted on 2023-11-08
3522 The impact of kit, environment and sampling contamination on the observed microbiome of bovine milk
Dean, C. J.; Deng, Y.; Wehri, T. J.; Ray, T.; Pena-Mosca, F.; Crooker, B. A.; Godden, S. M.; Caixeta, L. S.; Noyes, N.
10.1101/2023.11.07.566052 — microbiology — Posted on 2023-11-08
3531 Digitalized organoids: integrated pipeline for 3D high-speed analysis of organoid structures using multilevel segmentation and cellular topology
Ong, H. T.; Karatas, E.; Grenci, G.; Dilasser, F.; Raffi, S. B. M.; Blanc, D.; Poquillon, T. E.; Drimaracci, E.; Mikec, D.; Thiel, C.; Ullrich, O.; Racine, V.; Beghin, A.
10.1101/2023.11.08.566158 — cell biology — Posted on 2023-11-08
3533 Heart generation via blastocyst complementation in Mesp1/2-deficient mice
Abe, Y.; Sadahiro, T.; Fujita, R.; Yamada, Y.; Akiyama, T.; Nakano, K.; Honda, S.; Tanimoto, Y.; Suzuki, H.; Mizuno, S.; Takahashi, S.; Yamaguchi, T.; Masaki, H.; Hattori, K.; Mashimo, T.; Ieda, M.
10.1101/2023.11.08.565924 — cell biology — Posted on 2023-11-08
3535 Detection of a Mitochondrial Stress Phenotype using the Cell Painting Assay
Rezaei Adariani, S.; Agne, D.; Koska, S.; Burhop, A.; Warmers, J.; Janning, P.; Metz, M.; Pahl, A.; Sievers, S.; Waldmann, H.; Ziegler, S.
10.1101/2023.11.08.565491 — cell biology — Posted on 2023-11-08
3538 Dissection of figured wood trait in curly birch (Betula pendula var. carelica) using high-throughput genotyping
Gubaev, R.; Karzhaev, D.; Grigoreva, E.; Lytkin, K.; Safronycheva, E.; Volkov, V.; Nesterchuk, V.; Vetchinnikova, L.; Zhigunov, A.; Potokina, E.
10.1101/2023.11.07.566062 — plant biology — Posted on 2023-11-08
3539 Thermal imaging can reveal variation in stay-green functionality of wheat canopies under temperate conditions
Anderegg, J.; Kirchgessner, N.; Aasen, H.; Zumsteg, O.; Keller, B.; Zenkl, R.; Walter, A.; Hund, A.
10.1101/2023.11.08.566006 — plant biology — Posted on 2023-11-08
3542 Generation of human induced pluripotent stem cell (hiPSC) lines from patients with extreme high and low polygenic scores for QT interval
Mitchell, D.; Ullah, R.; Vanags, L.; Shen, A.; Jones, L.; ONeill, M.; Davogustto, G.; Shaffer, C.; Roden, D.; Shoemaker, B.; Williams, H.; Strickland, T.; Agee, T.; Johnson, C.; Kroncke, B.
10.1101/2023.11.03.565486 — genetics — Posted on 2023-11-08
3543 Decomposition of retinal ganglion cell electrical images for cell type and functional inference
Wu, E. G.; Rudzite, A. M.; Bohlen, M. O.; Li, P. H.; Kling, A.; Cooler, S.; Rhoades, C. E.; Brackbill, N.; Gogliettino, A. R.; Shah, N. P.; Madugula, S. S.; Sher, A.; Litke, A. M.; Field, G. D.; Chichilnisky, E. J.
10.1101/2023.11.06.565889 — neuroscience — Posted on 2023-11-08
3547 Identification of novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease
Date, Y.; Sasazawa, Y.; Kitagawa, M.; Gejima, K.; Suzuki, A.; Saya, H.; Imoto, M.; Itakura, E.; Hattori, N.; Saiki, S.
10.1101/2023.11.07.566147 — cell biology — Posted on 2023-11-08
3552 SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide (CGRP) signaling blockade reduces interleukin 6 (IL-6) release and weight loss in mouse models
Rahman, S. M.; Buchholz, D. W.; Imbiakha, B.; Jaeger, M. C.; Leach, J.; Osborn, R. M.; Birmingham, A. O.; Dewhurst, S.; Aguilar, H. C.; Luebke, A. E.
10.1101/2023.10.23.563669 — neuroscience — Posted on 2023-11-08
3559 The effect of pH alterations on TDP-43 in a cellular model of amyotrophic lateral sclerosis
Al Ojaimi, Y.; Slek, C.; Osman, S.; Alarcan, H.; Marouillat, S.; Corcia, P.; Vourc'h, P.; Lanznaster, D.; Blasco, H.
10.1101/2022.12.21.521010 — cell biology — Posted on 2023-11-08
3564 The brittle star genome illuminates the genetic basis of animal appendage regeneration
Parey, E.; Ortega-Martinez, O.; Delroisse, J.; Piovani, L.; Czarkwiani, A.; Dylus, D.; Arya, S.; Dupont, S.; Thorndyke, M.; Larsson, T.; Johannesson, K.; Buckley, K. M.; Martinez, P.; Oliveri, P.; Marletaz, F.
10.1101/2023.10.30.564762 — evolutionary biology — Posted on 2023-11-08
3568 SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns
Fukumura, K.; Sperotto, L.; Seuss, S.; Kang, H.-S.; Yoshimoto, R.; Sattler, M.; Mayeda, A.
10.1101/2022.12.30.522300 — molecular biology — Posted on 2023-11-08
3569 Multi-omics Quality Assessment in Personalized Medicine through EATRIS
EATRIS Plus Multi-omics working group and stakeholders, ; Scherer, A.
10.1101/2023.10.25.563912 — molecular biology — Posted on 2023-11-08
3572 Universal protection against SARS-CoV-2 viruses by multivalent mRNA vaccine in mice
Lei, Z.; Bian, S.; Zhai, S.; Yuan, X.; Wang, R.; Wang, P.; Pandey, V.; Zhang, C. Y.; Yu, D.; Chen, Z.; Qin, P.
10.1101/2023.11.05.565350 — immunology — Posted on 2023-11-08
3573 Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses
Micheva, K. D.; Gong, B.; Collman, F. C.; Weinberg, R. J.; Smith, S. J.; Trimmer, J.; Murray, K. D.
10.1101/2023.06.28.546920 — neuroscience — Posted on 2023-11-08
3574 Firing rate adaptation affords place cell theta sweeps, phase precession and procession
Chu, T.; Ji, Z.; Zuo, J.; Mi, Y.; Zhang, W.-H.; Huang, T.; Bush, D.; Burgess, N.; Wu, S.
10.1101/2022.11.14.516400 — neuroscience — Posted on 2023-11-08
3577 Investigating Antimicrobial Resistance Genes in Kenya, Uganda and Tanzania Cattle Using Metagenomics
Omar, K. M.; Kitundu, G. L.; Jimoh, A. O.; Namikelwa, D. N.; Lisso, F. M.; Babajide, A. A.; Olufemi, S. E.; Awe, O. I.
10.1101/2023.11.07.565943 — bioinformatics — Posted on 2023-11-08
3579 Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics
Waman, V. P.; Ashford, P.; Lam, S. D.; Sen, N.; Abbasian, M.; Woodridge, L.; Goldtzvik, Y.; Bordin, N.; Wu, J.; Sillitoe, I.; Orengo, C.
10.1101/2023.11.07.566012 — bioinformatics — Posted on 2023-11-08
3581 Sharing Massive Biomedical Data at Magnitudes Lower Bandwidth Using Implicit Neural Function
Yang, R.; Xiao, T.; Cheng, Y.; Li, A.; Qu, J.; Liang, R.; Bao, S.; Wang, X.; Suo, J.; Luo, Q.; Dai, Q.
10.1101/2022.12.03.518948 — bioinformatics — Posted on 2023-11-08
3582 An interface-based molecular generative framework for protein-protein interaction inhibitors
Wang, J.; Mao, J.; Li, C.; Xiang, H.; Wang, X.; Wang, S.; Wang, Z.; Chen, Y.; Li, Y.; Sun, H.; No, K. T.; Song, T.; Zeng, X.
10.1101/2023.10.10.557742 — bioinformatics — Posted on 2023-11-08
3584 Allosteric modulation by the fatty acid site in the glycosylated SARS-CoV-2 spike
Oliveira, A. S. F.; Kearns, F. L.; Rosenfeld, M. A.; Casalino, L. F.; Berger, I.; Schaffitzel, C.; Davidson, A. D.; Amaro, R. E.; Mulholland, A. J.
10.1101/2023.11.06.565757 — biochemistry — Posted on 2023-11-08
3589 CREaTor: zero-shot cis-regulatory pattern modeling with attention mechanisms
Li, Y.; Ju, F.; Chen, Z.; Qu, Y.; Xia, H.; He, L.; Wu, L.; Zhu, J.; Shao, B.; Deng, P.
10.1101/2023.03.28.534267 — genetics — Posted on 2023-11-08
3591 Lymphatic vessel development in human embryos
Yamaguchi, S.; Minamide, N.; Imai, H.; Ikeda, T.; Watanabe, M.; Imanaka-Yoshida, K.; Maruyama, K.
10.1101/2023.08.12.553102 — developmental biology — Posted on 2023-11-08
3594 Integrated multi-omics single cell atlas of the human retina
Li, J.; Wang, J.; Ibarra, I. L.; Cheng, X.; Luecken, M. D.; Lu, J.; Monavarfeshani, A.; Yan, W.; Zheng, Y.; Zuo, Z.; Colborn, S. L. Z.; Cortez, B. S.; Owen, L. A.; Tran, N. M.; Shekhar, K.; Sanes, J. R.; Stout, J. T.; Chen, S.; Li, Y.; DeAngelis, M. M.; Theis, F. J.; Chen, R.
10.1101/2023.11.07.566105 — molecular biology — Posted on 2023-11-08
3596 The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses
Bigotti, M. G.; Klein, K.; Gan, E. S.; Anastasina, M.; Andersson, S.; Vapalahti, O.; Katajisto, P.; Erdmann, M.; Davidson, A. D.; Butcher, S. J.; Collinson, I.; Ooi, E. E.; Balistreri, G.; Brancaccio, A.; Yamauchi, Y.
10.1101/2023.11.06.565781 — microbiology — Posted on 2023-11-08
3597 The Vacant Niche Revisited: Using Negative Results to Refine the Limits of Habitability
Graham, H. V.; Ratliff, L. E.; Fulford, A.; Pozarycki, C. I.; Wimp, G. M.; Nichols, F.; Osburn, M.
10.1101/2023.11.06.565904 — microbiology — Posted on 2023-11-08
3599 Dynamic ventral disc contraction is necessary for Giardia attachment and host pathology
Nosala, C.; Hagen, K. D.; Guest, S. L.; Hilton, N. A.; Mueller, A.; Laue, M.; Klotz, C.; Aebischer, A.; Dawson, S. C.
10.1101/2023.07.04.547600 — microbiology — Posted on 2023-11-08
3602 The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance.
De Lay, N. R.; Verma, N.; Sinha, D.; Garrett, A.; Osterberg, M.; Reiling, S.; Porter, D.; Giedroc, D. P.; Winkler, M. E.
10.1101/2023.11.07.565944 — microbiology — Posted on 2023-11-08
3603 Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates
Gagne, M.; Flynn, B. J.; Andrew, S. F.; Flebbe, D. R.; Mychalowych, A.; Lamb, E.; Davis-Gardner, M. E.; Burnett, M. R.; Serebryannyy, L. A.; Lin, B. C.; Pessaint, L.; Todd, J.-P. M.; Ziff, Z. E.; Maule, E.; Carroll, R.; Naisan, M.; Jethmalani, Y.; Case, J. B.; Dmitriev, I. P.; Kashentseva, E. A.; Ying, B.; Dodson, A.; Kouneski, K.; Doria-Rose, N. A.; O'Dell, S.; Godbole, S.; Laboune, F.; Henry, A. R.; Marquez, J.; Teng, I.-T.; Wang, L.; Zhou, Q.; Wali, B.; Ellis, M.; Zouantchangadou, S.; Van Ry, A.; Lewis, M. G.; Andersen, H.; Kwong, P. D.; Curiel, D. T.; Foulds, K. E.; Nason, M. C.; Suthar, M
10.1101/2023.11.06.565765 — immunology — Posted on 2023-11-08
3609 Single-cell transcriptomic and genomic changes in the aging human brain
Jeffries, A. M.; Yu, T.; Ziegenfuss, J. S.; Tolles, A. K.; Kim, Y.; Weng, Z.; Lodato, M. A.
10.1101/2023.11.07.566050 — genomics — Posted on 2023-11-07
3611 Transcriptomic changes during the replicative senescence of human articular chondrocytes
Atasoy-Zeybek, A.; Hawse, G. P.; Nagelli, C. V.; Lopez De Padilla, C.; Abdel, M. P.; Evans, C. H.
10.1101/2023.11.07.565835 — cell biology — Posted on 2023-11-07
3612 Mitochondrial One-Carbon Metabolism is Required for TGF-β-Induced Glycine Synthesis and Collagen Protein Production
Meliton, A. Y.; Cetin-Atalay, R.; Tian, Y.; Szafran, J. C.; Shin, K. W. D.; Cho, T.; Sun, K. A.; Woods, P. S.; Shamaa, O. R.; Chen, B.; Muir, A.; Mutlu, G. M.; Hamanaka, R. B.
10.1101/2023.11.07.566074 — cell biology — Posted on 2023-11-07
3614 The immune landscape of murine skeletal muscle regeneration and aging
Sousa, N. S.; Bica, M.; Bras, M. F.; Antunes, I. A.; Encarnacao, I. A.; Costa, T.; Martins, I. B.; Barbosa-Morais, N. L.; Sousa-Victor, P.; Neves, J.
10.1101/2023.11.07.565995 — cell biology — Posted on 2023-11-07
3615 A vasopressin circuit that modulates sex-specific social interest and anxiety-like behavior in mice
Rigney, N.; Campos-Lira, E.; Kirchner, M. K.; Wei, W.; Belkasim, S.; Beaumont, R.; Singh, S.; Sterm, J. E.; de Vries, G. J.; Petrulis, A.
10.1101/2023.11.06.564847 — neuroscience — Posted on 2023-11-07
3616 The Spatial Frequency Representation Predicts Category Coding in the Inferior Temporal Cortex
Toosi, R.; Karami, B.; Koushki, R.; Shakerian, F.; Noroozi, J.; Rezayat, E.; Vahabie, A.-H.; Akhaee, M. A.; Dehaqani, M.-R. A.
10.1101/2023.11.07.566068 — neuroscience — Posted on 2023-11-07
3617 A multi-faceted analysis of synapses reveals the role of neuroligin-1 cleavage in presynaptic vesicle accumulation in the lateral amygdala
Thomas, C. I.; Anderson, J. R.; Alexis, A.; Guerrero-Given, D.; Chavez, A.; McNabb, M. C.; Unal, B.; Ehlers, M. D.; Bolton, M. M.; Kamasawa, N.
10.1101/2023.11.07.566075 — neuroscience — Posted on 2023-11-07
3619 Brain-Age Prediction: Systematic Evaluation of Site Effects, and Sample Age Range and Size
Yu, Y.; Cui, H.; Haas, S.; New, F.; Sanford, N.; Yu, K.; Zhan, D.; Yang, G.; Gao, J.-H.; Wei, D.; Qiu, J.; Bernhardt, B.; Thompson, P.; Frangou, S.; Ge, R.; ENIGMA World Aging Center,
10.1101/2023.11.06.565917 — bioinformatics — Posted on 2023-11-07
3623 Virtual tissue microstructure reconstruction across species using generative deep learning
Bettancourt, N.; Perez, C.; Candia, V.; Guevara, P.; Kalaidzidis, Y.; Zerial, M.; Segovia-Miranda, F.; Morales-Navarrete, H.
10.1101/2023.06.12.544541 — bioinformatics — Posted on 2023-11-07
3626 The modified RNA base acp3U is an attachment site for N-glycans in glycoRNA
Xie, Y.; Hemberger, H.; Till, N. A.; Chai, P.; Watkins, C.; Lebedenko, C. G.; Caldwell, R. M.; George, B.; Bertozzi, C. R.; Garcia, B. A.; Flynn, R. A.
10.1101/2023.11.06.565735 — molecular biology — Posted on 2023-11-07
3627 A Remarkable Genetic Shift in a Transmitted/Founder Virus Broadens Antibody Responses Against HIV-1
Jain, S.; Uritskiy, G.; Mahalingam, M.; Batra, H.; Chand, S.; Trinh, H.; Beck, C.; Shin, W.-H.; AlSalmi, W.; Kijak, G.; Eller, L. A.; Kim, J.; Kihara, D.; Tovanabutra, S.; Ferrari, G.; Robb, M.; Rao, M.; Rao, V. B.
10.1101/2021.06.16.448593 — microbiology — Posted on 2023-11-07
3628 Exposure to nitric oxide drives transition to differential culturability in Mycobacterium tuberculosis
Glenn, S. M.; Gap-Gaupool, B.; Milburn, E.; Turapov, O.; Crosatti, M.; Hincks, J.; Stewart, B.; Bacon, J.; Kendall, S. L.; Voskuil, M. I.; Riabova, O.; Monakhova, N.; Green, J.; Waddell, S. J.; Makarov, V.; Mukamolova, G. V.
10.1101/2021.09.28.462152 — microbiology — Posted on 2023-11-07
3631 Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats
Sun, J.; yang, x.; Carmichael, A.; Kim, T. J.; Kim, Y.-J.; Wei, Z.; Han, L.; Stanciu, N.; Ko, S.-B.; Nan, G.; Yoon, B.-W.
10.1101/2023.09.22.558889 — neuroscience — Posted on 2023-11-07
3632 Visual stimuli modulate local field potentials but drive no high-frequency activity in human auditory cortex
Ahveninen, J.; Lee, H.-J.; Yu, H.-Y.; Lee, C.-C.; Chou, C.-C.; Ahlfors, S. P.; Kuo, W.-J.; Jääskeläinen, I. P.; Lin, F.-H.
10.1101/2022.07.18.500417 — neuroscience — Posted on 2023-11-07
3633 Enhancing Hi-C contact matrices for loop detection with Capricorn, a multi-view diffusion model
Fang, T.; Liu, Y.; Woicik, A.; Lu, M.; Jha, A.; Wang, X.; Li, G.; Hristov, B.; Liu, Z.; Xu, H.; Noble, W. S.; Wang, S.
10.1101/2023.10.25.564065 — bioinformatics — Posted on 2023-11-07
3635 WITHDRAWN: Isolation and Characterization of the Lytic Bacteriophages and Its Application in Combination with Amoxicillin against Aeromonas dhakensis
Sawaengwong, T.; Sunthornthummas, S.; Wongyoo, R.; Surachat, K.; Rangsiruji, A.; Atithep, T.; Sarawaneeyaruk, S.; Doi, K.; Nantavisai, K.; Insian, K.; Pomwised, R.; Pringsulaka, O.
10.1101/2022.12.01.518801 — microbiology — Posted on 2023-11-07
3637 Sex differences in neural representations of social and nonsocial reward in the medial prefrontal cortex.
Isaac, J.; Karkare, S.; Balasubramanian, H.; Schappaugh, N.; Javier, J.; Rashid, M.; Murugan, M.
10.1101/2023.03.09.531947 — neuroscience — Posted on 2023-11-07
3639 MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation
Guerin, C. M.; Vinchent, A.; Fernandes, M.; Damour, I.; Laratte, A.; Tellier, R.; Estevam, G. O.; Meneboo, J.-P.; Villenet, C.; Descarpentries, C.; Fraser, J. S.; Figeac, M.; Cortot, A. B.; Rouleau, E.; Tulasne, D.
10.1101/2023.11.03.565283 — cancer biology — Posted on 2023-11-07
3641 In situ architecture of Opa1-dependent mitochondrial cristae remodeling
Fry, M. Y.; Navarro, P. P.; Hakim, P.; Ananda, V. Y.; Qin, X.; Landoni, J. C.; Rath, S.; Inde, Z.; Lugo, C. M.; Luce, B. E.; Ge, Y.; McDonald, J. L.; Ali, I.; Ha, L. L.; Kleinstiver, B. P.; Chan, D. C.; Sarosiek, K.; Chao, L. H.
10.1101/2023.01.16.524176 — biophysics — Posted on 2023-11-07
3642 FICTURE: Scalable segmentation-free analysis of submicron resolution spatial transcriptomics
Si, Y.; Lee, C.; Hwang, Y.; Yun, J. H.; Cheng, W.; Cho, C.-S.; Quiros, M.; Nusrat, A.; Zhang, W.; Jun, G.; Zoellner, S.; Lee, J. H.; Kang, H. M.
10.1101/2023.11.04.565621 — bioinformatics — Posted on 2023-11-07
3645 Ongoing convergent evolution of a selfing syndrome threatens plant-pollinator interactions
Acoca-Pidolle, S.; Gauthier, P.; Devresse, L.; Deverge Merdrignac, A.; Pons, V.; Cheptou, P.-O.
10.1101/2023.05.25.542270 — evolutionary biology — Posted on 2023-11-07
3647 Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells
Hargrave, K. E.; Worrell, J. C.; Pirillo, C.; Brennan, E.; Masdefiol Garriga, A.; Gray, J. I.; Purnell, T.; Roberts, E. W.; MacLeod, M. K.
10.1101/2023.09.19.558387 — immunology — Posted on 2023-11-07
3652 Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly
Benning, F. M. C.; Jenni, S.; Garcia, C. Y.; Nguyen, T. H.; Zhang, X.; Chao, L. H.
10.1101/2023.06.15.545104 — biophysics — Posted on 2023-11-07
3653 Genetic sex determination in three closely related hydrothermal vent gastropods, including one species with intersex individuals
Castel, J.; Pradillon, F.; Cueff, V.; Daguin-Thiebaut, C.; Ruault, S.; Mary, J.; Hourdez, S.; Jollivet, D.; Broquet, T.
10.1101/2023.04.11.536409 — evolutionary biology — Posted on 2023-11-07
3655 SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction
Flaherty, S. E.; Bezy, O.; Paulhus, B. L.; Song, L.; Piper, M.; Pang, J.; Park, Y.; Asano, S.; Lien, Y.-C.; Griffin, J. D.; Robertson, A.; Opsahl, A.; Shanthappa, D. H.; Ahn, Y.; Pashos, E.; Simmons, R. A.; Birnbaum, M. J.; Wu, Z.
10.1101/2023.09.05.555087 — molecular biology — Posted on 2023-11-07
3656 Activity in the reticulospinal tract scales with handgrip force in humans
Danielson, T. L.; Gould, L.; DeFreitas, J. M.; MacLennan, R. J.; Ekstrand, C.; Borowsky, R.; Farthing, J. P.; Andrushko, J. W.
10.1101/2023.10.27.563544 — neuroscience — Posted on 2023-11-07
3657 Connectome-Based Attractor Dynamics Underlie Brain Activity in Rest, Task, and Disease
Englert, R.; Kincses, B.; Kotikalapudi, R.; Gallitto, G.; Li, J.; Hoffschlag, K.; Woo, C.-W.; Wager, T.; Timmann, D.; Bingel, U.; Spisak, T.
10.1101/2023.11.03.565516 — neuroscience — Posted on 2023-11-07
3658 A disinhibitory circuit mechanism explains a general principle of peak performance during mid-level arousal
Beerendonk, L.; Mejias, J. F.; Nuiten, S. A.; de Gee, J. W.; Fahrenfort, J. J.; van Gaal, S.
10.1101/2023.07.28.550956 — neuroscience — Posted on 2023-11-07
3661 Tweek-dependent formation of ER-PM contact sites enables astrocyte phagocytic function and remodeling of neurons
Kang, Y.; Jefferson, A.; Sheehan, A.; De La Torre, R.; Jay, T.; Chiao, L.; Hulegaard, A.; Corty, M. M.; Baconguis, I.; Zhou, Z.; Freeman, M.
10.1101/2023.11.06.565932 — neuroscience — Posted on 2023-11-07
3662 Repression of pattern-triggered immune responses by hypoxia
Mooney, B. C.; Doorly, C. M.; Mantz, M.; Garcia, P.; Huesgen, P. F.; Graciet, E.
10.1101/2023.11.07.565979 — plant biology — Posted on 2023-11-07
3665 biomapp::chip: Large-Scale Motif Analysis
Caldonazzo Garbelini, J. M.; Sanches, D. S.; Ramirez Pozo, A. T.
10.1101/2023.11.06.565033 — bioinformatics — Posted on 2023-11-07
3667 Structure-based design of small molecule inhibitors of the cagT4SS ATPase Cagα of Helicobacter pylori
Morin, C.; Verma, V. T.; Arya, T.; Casu, B.; Jolicoeur, E.; Ruel, R.; Marinier, A.; Sygusch, J.; Baron, C.
10.1101/2023.11.06.565890 — biochemistry — Posted on 2023-11-07
3669 Plasma neurofilament light protein provides evidence of accelerated brain ageing in treatment-resistant schizophrenia
Wannan, C. M. J.; Eratne, D.; Santillo, A.; Malpas, C.; Cilia, B.; Dean, O. M.; Walker, A.; Berk, M.; Bousman, C.; Everall, I.; Velakoulis, D.; Pantelis, C.
10.1101/2023.11.06.565715 — neuroscience — Posted on 2023-11-07
3671 Histone H1x in mouse ventral hippocampus correlates with, but does not cause behavioral adaptations to stress
Kim, R. K.; Truby, N. L.; Silva, G. M.; Picone, J. A.; Miller, C. S.; Neve, R. L.; Cui, X.; Hamilton, P. J.
10.1101/2023.11.06.565881 — neuroscience — Posted on 2023-11-07
3673 Global analysis of the heparin-enriched plasma proteome captures matrisome-associated proteins in Alzheimer's disease
Guo, Q.; Ping, L.; Dammer, E. B.; Duong, D. M.; Yin, L.; Xu, K.; Shantaraman, A.; Fox, E. J.; Johnson, E. C. B.; Roberts, B. R.; Lah, J. J.; Levey, A. I.; Seyfried, N. T.
10.1101/2023.11.06.565824 — neuroscience — Posted on 2023-11-07
3675 A single-cell multi-omic and spatial atlas of nodal B-cell lymphomas reveals B-cell maturation drives intratumor heterogeneity
Fitzgerald, D.; Roider, T.; Baertsch, M. A.; Kibler, A.; Horlova, A.; Chung, E. K.; Voehringer, H.; Mathioudaki, A.; Budeus, B.; Passerini, V.; Knoll, M.; Mammen, J.; Li, L.; Caille, L.; Czernilofsky, F.; Bruch, P. M.; Liebers, N.; Meyer-Bender, M.; Weigert, O.; Zaugg, J. B.; Nolan, G. P.; Seifert, M.; Huber, W.; Dietrich, S.
10.1101/2023.11.06.565756 — cancer biology — Posted on 2023-11-07
3676 Teaching transposon classification as a means to crowd source the curation of repeat annotation - a tardigrade perspective
Peona, V.; Martelossi, J.; Almojil, D.; Bocharkina, J.; Brännström, I.; Brown, M.; Cang, A.; Carrasco-Valenzuela, T.; DeVries, J.; Doellman, M.; Elsner, D.; Espindola-Hernandez, P.; Friis, G.; Gaspar, B.; Zagorski, D.; Hałakuc, P.; Ivanovska, B.; Laumer, C.; Lehmann, R.; Bostjancic, L. L.; Mashoodh, R.; Mazzoleni, S.; Mouton, A.; Janke, M. N.; Pei, Y.; Potente, G.; Provataris, P.; Pardos-Blas, J. R.; Raut, R.; Sbaffi, T.; Schwarz, F.; Stapley, J.; Stevens, L.; Sultana, N.; Symonova, R.; Tahami, M. S.; Urzi, A.; Yang, H.; Yusuf, A.; Pecoraro, C.; Suh, A.
10.1101/2023.11.06.565293 — evolutionary biology — Posted on 2023-11-07
3679 Simultaneous analysis of pMHC binding and reactivity unveils virus-specific CD8 T cell immunity to a concise epitope set
Kristensen, N. P.; Dionisio, E.; Bentzen, A. K.; Tamhane, T.; Kemming, J. S.; Nos, G.; Voss, L. F.; Hansen, U. K.; Lauer, G. M.; Hadrup, S. R.
10.1101/2023.11.06.565606 — immunology — Posted on 2023-11-07
3684 Synapses are uniquely vulnerable to sleep loss during brain development while maturation confers resilience
Gay, S. M.; Chartampila, E.; Lord, J. S.; Grizzard, S.; Maisashvili, T.; Ye, M.; Barker, N. K.; Mordant, A. L.; Mills, C. A.; Herring, L. E.; Diering, G. H.
10.1101/2023.11.06.565853 — neuroscience — Posted on 2023-11-07
3685 The Arabidopsis Information Resource in 2024
Reiser, L.; Bakker, E.; Subramaniam, S.; Chen, X.; Sawant, S.; Khosa, K.; Prithvi, T.; Berardini, T. Z.
10.1101/2023.11.06.565838 — plant biology — Posted on 2023-11-07
3686 Early inflammatory response mediated by Angiotensin II in cardiac arteries of normotensive mice.
Oliveira, T. C. d. S.; Viegas, K. A. d. S.; Lima, R. S. d.; Campos, L. C. G.; Barauna, V. G.; Curi, R.; Irigoyen, M. C.; Lacchini, S.
10.1101/2023.11.06.563831 — physiology — Posted on 2023-11-07
3690 Differential quantification of alternative splicing events on spliced pangenome graphs
Ciccolella, S.; Cozzi, D.; Della Vedova, G.; Kuria, S.; Bonizzoni, P.; Denti, L.
10.1101/2023.11.06.565751 — bioinformatics — Posted on 2023-11-07
3691 Cutaneous T cell lymphoma atlas reveals malignant Th2 cells supported by a B cell-rich microenvironment
Li, R.; Strobl, J.; Poyner, E. F. M.; Torabi, F.; Mazin, P.; Chipampe, N.-J.; Stephenson, E.; Gardner, L.; Olabi, B.; Coulthard, R.; Botting, R. A.; Zila, N.; Prigmore, E.; Gopee, N.; Engelbert, J.; Goh, I.; Chan, H. M.; Johnson, H.; Ellis, J.; Rowe, V.; Tun, W.; Reynolds, G.; Foster, A. R.; Gambardella, L.; Winheim, E.; Admane, C.; Rumney, B.; Steele, L.; Jardine, L.; Nenonen, J.; Pickard, K.; Lumley, J.; Hampton, P.; Hu, S.; Liu, F.; Liu, X.; Horsfall, D.; Basurto-Lozada, D.; Grimble, L.; Bacon, C. M.; Weatherhead, S.; Brauner, H.; Wang, Y.; Bai, F.; Reynolds, N. J.; Allen, J. E.; Jonak, C.;
10.1101/2023.11.06.565474 — genomics — Posted on 2023-11-07
3692 A paradoxical population structure of var DBLα types in Africa
Tan, M. H.; Tiedje, K. E.; Feng, Q.; Zhan, Q.; Pascual, M.; Shim, H. S.; Chan, Y.-b.; Day, K. P.
10.1101/2023.11.05.565723 — genetics — Posted on 2023-11-07
3693 Genome assembly of the dyeing poison frog provides insights into the dynamics of transposable element and genome-size evolution
Dittrich, C.; Hoelzl, F.; Smith, S.; Fouilloux, C. A.; Parker, D.; O'Connell, L. A.; Knowles, L. S.; Hughes, M.; Fewings, A.; Morgan, R.; Rojas, B.; Comeault, A. A.
10.1101/2023.11.06.565769 — genetics — Posted on 2023-11-07
3694 How collectively integrated are ecological communities?
Zelnik, Y.; Galiana, N.; Barbier, M.; Loreau, M.; Galbraith, E.; Arnoldi, J.-F.
10.1101/2022.12.29.522189 — ecology — Posted on 2023-11-07
3696 Nucleocapsid condensation drives Ebola viral factory maturation and dispersion
Vallbracht, M.; Bodmer, B. S.; Fischer, K.; Winter, S. L.; Wendt, L.; Wachsmuth-Melm, M.; Hoenen, T.; Chlanda, P.
10.1101/2023.11.06.565679 — microbiology — Posted on 2023-11-07
3703 Improving the reliability of fMRI-based predictions of intelligence via semi-blind machine learning
Lohmann, G.; Heczko, S.; Mahler, L.; Wang, Q.; Steiglechner, J.; Kumar, V. J.; Roost, M.; Jost, J.; Scheffler, K.
10.1101/2023.11.03.565485 — neuroscience — Posted on 2023-11-07
3704 Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis
Wiese, C.; Abele, M.; Al, B.; Altmann, M.; Steiner, A.; Kalbfuss, N.; Strohmayr, A.; Ravikumar, R.; Park, C. H.; Brunschweiger, B.; Meng, C.; Facher, E.; Ehrhardt, D. W.; Falter-Braun, P.; Wang, Z.-Y.; Ludwig, C.; Assaad, F. F.
10.1101/2023.04.24.537966 — plant biology — Posted on 2023-11-07
3705 Spatial protein and RNA analysis on the same tissue section using MICS technology
Neil, E.; Park, D.; Hennessey, R. C.; DiBiasio, E. C.; DiBuono, M.; Lafayette, H.; Lloyd, E.; Lo, H.; Femel, J.; Makrigiorgos, A.; Soliman, S.; Mangiardi, D.; Praveen, P.; Rüberg, S.; Staubach, F.; Hindman, R.; Rothmann, T.; Meyer, H.; Wantenaar, T.; Wang, J.; Müller, W.; Pinard, R.; Bosio, A.
10.1101/2023.10.27.564191 — molecular biology — Posted on 2023-11-07
3706 RNA structure modulates Cas13 activity and enables mismatch detection
Kimchi, O.; Larsen, B. B.; Dunkley, O. R.; te Velthuis, A. J. W.; Myhrvold, C.
10.1101/2023.10.05.560533 — molecular biology — Posted on 2023-11-07
3707 The GLM-Spectrum: A multilevel framework for spectrum analysis with covariate and confound modelling
Quinn, A. J.; Atkinson, L. Z.; Gohil, C.; Kohl, O.; Pitt, J.; Zich, C.; Nobre, A. C.; Woolrich, M. W.
10.1101/2022.11.14.516449 — neuroscience — Posted on 2023-11-07
3708 Microbial functional pathways based on metatranscriptomic profiling enable effective saliva-based health assessments for precision wellness
Patridge, E.; Gorakshakar, A.; Molusky, M. M.; Ogundijo, O.; Janevski, A.; Julian, C.; Hu, L.; Vuyisich, M.; Banavar, G.
10.1101/2023.11.01.565122 — systems biology — Posted on 2023-11-07
3709 CATD: A reproducible pipeline for selecting cell-type deconvolution methods across tissues
Vathrakokoili Pournara, A.; Miao, Z.; Beker, O. Y.; Nolte, N. F.; Brazma, A.; Papatheodorou, I.
10.1101/2023.01.19.523443 — bioinformatics — Posted on 2023-11-07
3712 Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid
Fita-Torro, J.; Garrido-Huarte, J. L.; Michel, A. H.; Kornmann, B.; Pascual-Ahuir, A.; Proft, M.
10.1101/2023.11.06.565743 — molecular biology — Posted on 2023-11-07
3713 HDAC inhibitors rescue MeCP2T158M speckles in a high content screen
Lata, R.; Steegmans, L.; Kellens, R.; Nijs, M.; Klaassen, H.; Versele, M.; Christ, F.; Debyser, Z.
10.1101/2023.11.02.565272 — neuroscience — Posted on 2023-11-07
3714 Fluorescent Peptide-based Probe for the Detection of Alpha-synuclein Aggregates in the Gut
Sim, R.; Lee, J.; Chieng, J.; Tan, K. H.; Lim, G.; Foo, A.; Wong, S. H.; Lim, K. L.; Liang, K.
10.1101/2023.11.06.565731 — neuroscience — Posted on 2023-11-07
3715 EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells
Gallardo, A.; Lopez-Onieva, L.; Belmonte-Reche, E.; Fernandez-Rengel, I.; Serrano-Prados, A.; Molina, A.; Sanchez-Pozo, A.; Landeira, D.
10.1101/2023.03.13.532335 — cancer biology — Posted on 2023-11-07
3716 Exploration of Mechanisms of Drug Resistance in a Microfluidic Device and Patient Tissues
Lim, W.; Hwang, I.; Zhang, J.; Chen, Z.; Han, J.; Jeon, J.; Koo, B.-K.; Kim, S.; Lee, J. E.; Kim, Y.; Pienta, K. J.; Amend, S. R.; Austin, R. H.; Ahn, J.-Y.; Park, S.
10.1101/2022.11.14.515727 — cancer biology — Posted on 2023-11-07
3717 Pauperization of Emerin from nuclear envelope drives prostate cancer cell migration and invasiveness
Nastaly, P.; Popeda, M.; Kowalski, K.; Wenta, T.; Beznoussenko, G.; Rychlowski, M.; Mironov, A.; Lavagnino, Z.; Barozzi, S.; Richert, J.; Bertolio, R.; Szade, J.; Miszewski, K.; Matuszewski, M.; Zaczek, A. J.; Braga, L.; Del Sal, G.; Bednarz-Knoll, N.; Maiuri, P.
10.1101/2023.11.06.565767 — cancer biology — Posted on 2023-11-07
3720 BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration
Vargas, J. N. S.; Brown, A.-L.; Sun, K.; Hagemann, C.; Geary, B.; Villarroel-Campos, D.; Bryce-Smith, S.; Zanovello, M.; Lombardo, M.; Ryandov, E.; Stepic, A.; Meysman, L.; Majewski, S.; Tosolini, A.; Secrier, M.; Keuss, M. J.; Serio, A.; Sleigh, J. N.; Fratta, P.; Schiavo, G.
10.1101/2023.11.06.565775 — molecular biology — Posted on 2023-11-07
3722 SPIRO - the automated Petri plate imaging platform designed by biologists, for biologists
Ohlsson, J. A.; Leong, J. X.; Elander, P. H.; Ballhaus, F.; Holla, S.; Dauphinee, A. N.; Johansson, J.; Lommel, M.; Hofmann, G.; Betner, S.; Sandgren, M.; Schumacher, K.; Bozhkov, P. V.; Minina, E. A.
10.1101/2021.03.15.435343 — plant biology — Posted on 2023-11-07
3725 Conformation Selection by ATP-competitive Inhibitors and Allosteric Communication in ERK2
Anderson, J. W.; Vaisar, D.; Jones, D. N.; Pegram, L. M.; Vigers, G. P.; Chen, H.; Moffat, J. G.; Ahn, N. G.
10.1101/2023.09.12.557258 — biochemistry — Posted on 2023-11-06
3726 IQCH regulates spermatogenesis by interacting with CaM to promote the expression of RNA-binding proteins
Ruan, T.; Zhou, R.; Yang, Y.; Guo, J.; Jiang, C.; Wang, X.; Shen, G.; Dai, S.; Chen, S.; Shen, Y.
10.1101/2023.06.23.546221 — genetics — Posted on 2023-11-06
3727 Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
Hagihara, H.; Shoji, H.; Hattori, S.; Sala, G.; Takamiya, Y.; Tanaka, M.; Ihara, M.; Shibutani, M.; Hatada, I.; Hori, K.; Hoshino, M.; Nakao, A.; Mori, Y.; Okabe, S.; Matsushita, M.; Urbach, A.; Katayama, Y.; Matsumoto, A.; Nakayama, K. I.; Katori, S.; Sato, T.; Iwasato, T.; Nakamura, H.; Goshima, Y.; Raveau, M.; Tatsukawa, T.; Yamakawa, K.; Kasai, H.; Takahashi, N.; Inazawa, J.; Nobuhisa, I.; Kagawa, T.; Taga, T.; Darwish, M.; Nishizono, H.; Takao, K.; Sapkota, K.; Nakazawa, K.; Takagi, T.; Fujisawa, H.; Sugimura, Y.; Yamanishi, K.; Rajagopal, L.; Hannah, N. D.; Meltzer, H. Y.; Yamamoto, T.;
10.1101/2021.02.02.428362 — neuroscience — Posted on 2023-11-06
3728 New learning principles emerge from biomimetic computational primitives
Pathak, A.; Brincat, S. L.; Organtzidis, H.; Strey, H. H.; Senneff, S.; Antzoulatos, E. G.; Mujica-Parodi, L. R.; Miller, E. K.; Granger, R.
10.1101/2023.11.06.565902 — neuroscience — Posted on 2023-11-06
3729 Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex
Kim, S. N.; Viswanadham, V. V.; Doan, R. N.; Dou, Y.; Bizzotto, S.; Khoshkoo, S.; Huang, A. Y.; Yeh, R.; Chhouk, B.; Truong, A.; Chappell, K. M.; Beaudin, M.; Barton, A. R.; Akula, S. K.; Rento, L.; Lodato, M.; Ganz, J.; Szeto, R. A.; Li, P.; Tsai, J. W.; Hill, R. S.; Park, P. J.; Walsh, C. A.
10.1101/2023.11.06.565899 — neuroscience — Posted on 2023-11-07
3730 The how, when, and what of odor valence communication between the olfactory bulb and piriform cortex
Norden, F.; Iravani, B.; Schaefer, M.; Winter, A. L.; Lundqvist, M.; Arshamian, A.; Lundström, J. N.
10.1101/2023.11.02.564696 — neuroscience — Posted on 2023-11-07
3732 Tumor-specific neutrophils originating from meninges promote glioblastoma
Zhao, J.; Wu, D.; Liu, J.; Zhang, Y.; Cao, P.; Li, C.; Wu, S.; Li, M.; Cui, Y.; Sun, Y.; Li, W.; Yang, E.; Ji, N.; Yang, J.; Chen, J.
10.1101/2023.05.23.542010 — cancer biology — Posted on 2023-11-06
3735 tauFisher accurately predicts circadian time from a single sample of bulk and single-cell transcriptomic data
Duan, J.; Ngo, M. N.; Karri, S. S.; Tsoi, L. C.; Gudjonsson, J. E.; Shahbaba, B.; Lowengrub, J.; Andersen, B.
10.1101/2023.04.04.535473 — bioinformatics — Posted on 2023-11-06
3736 Hidden rAAV Breakpoints Detected Using Single-Molecule, Modified Base Sequencing
Hanscom, T.; Soares, L. M. M.; Zheng, A.; Bourgeois, N.; Gall, K.; St. Martin, T.; Wright, J.; Selby, D. E.
10.1101/2023.11.06.565870 — genomics — Posted on 2023-11-06
3738 Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
Goettemoeller, A. M.; Banks, E.; McCann, K. E.; Kumar, P.; South, K.; Olah, V. J.; Ramelow, C. C.; Duong, D. M.; Seyfried, N. T.; Rangaraju, S.; Weinshenker, D.; Rowan, M. J.
10.1101/2023.11.06.565629 — neuroscience — Posted on 2023-11-06
3741 Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro, L.; Nakata, Y.; Borges, R. L.; Garcia-Martinez, L.; Banuelos, C.; Stransky, S.; Chan, H. L.; Brabson, J.; Dominguez, D.; Zhang, Y.; Lewis, P. W.; Benitah, S. A.; Cimmino, L.; Bilbao, D.; Sidoli, S.; Verdun, R.; Morey, L.
10.1101/2023.11.06.565847 — cancer biology — Posted on 2023-11-06
3744 Blood transcriptomics analysis offers insights into variant-specific immune response to SARS-CoV-2
Hoffmann, M.; Willruth, L.-L.; Dietrich, A.; Lee, H. K.; Knabl, L.; Trummer, N.; Baumbach, J.; Furth, P. A.; Hennighausen, L.; List, M.
10.1101/2023.11.03.564190 — bioinformatics — Posted on 2023-11-06
3746 Targeting phosphoRab-RILPL Interactions as a Strategy to Downregulate Pathogenic LRRK2 in Parkinson's Disease
Alexander, K.; Naaldijk, Y.; Fasiczka, R.; Brahmia, B.; Chen, T.; Hilfiker, S.; Kennedy, E. J.
10.1101/2023.11.06.565863 — biochemistry — Posted on 2023-11-06
3747 Inference of Locus-Specific Population Mixtures From Linked Genome-Wide Allele Frequencies
Reyna-Blanco, C. S.; Caduff, M.; Galimberti, M.; Leuenberger, C.; Wegmann, D.
10.1101/2023.11.06.565831 — genomics — Posted on 2023-11-06
3749 Genomic insights into the evolution of secondary metabolism of Escovopsis and its allies, specialized fungal symbionts of fungus-farming ants
Berasategui, A.; Salem, H.; Moller, A.; Christopher, Y.; Montoya, Q. V.; Conn, C. E.; Read, T. D.; Rodrigues, A.; Ziemert, N.; Gerardo, N. M.
10.1101/2023.11.06.564974 — evolutionary biology — Posted on 2023-11-06
3750 Long-term serial passaging of SARS-CoV-2 reveals signatures of convergent evolution
Foster, C. S. P.; Walker, G. J.; Jean, T.; Wong, M.; Brassil, L.; Isaacs, S.; Lu, Y.; Turville, S. G.; Kelleher, A.; Rawlinson, W. D.
10.1101/2023.11.02.565396 — evolutionary biology — Posted on 2023-11-06
3751 Using natural language processing to extract plant functional traits from unstructured text
Domazetoski, V.; Kreft, H.; Bestova, H.; Wieder, P.; Koynov, R.; Zarei, A.; Weigelt, P.
10.1101/2023.11.06.565787 — ecology — Posted on 2023-11-06
3753 Voltage-gated T-type calcium channel blockers reduce apoptotic body-mediated SARS-CoV-2 cell-to-cell spread and subsequent cytokine storm
Phan, T. K.; Sheerin, D.; Shi, B.; Dayton, M.; Mackiewicz, L.; Ozkocak, D. C.; Atkin-Smith, G.; Peton, N.; Audi, O.; Tixeira, R.; Ashdown, G.; Davidson, K. C.; Doerflinger, M.; Coussens, A. K.; Poon, I. K. H.
10.1101/2023.11.03.565419 — cell biology — Posted on 2023-11-06
3755 Mime-seq 2.0: a method to sequence microRNAs from specific mouse cell types
Mandlbauer, A.; Sun, Q.; Popitsch, N.; Schwickert, T.; Spanova, M.; Wang, J.; Ameres, S. L.; Busslinger, M.; Cochella, L.
10.1101/2023.11.06.565867 — molecular biology — Posted on 2023-11-06
3756 Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19
An, A.; Baghela, A.; Zhang, P.; Blimkie, T. M.; Gauthier, J.; Kaufmann, D. E.; Acton, E.; Lee, A. H.; Levesque, R. C.; Hancock, R. E. W.
10.1101/2023.11.04.565404 — immunology — Posted on 2023-11-06
3758 Tissue-resident alveolar macrophages reduce O3-induced inflammation via MerTK mediated efferocytosis
Guttenberg, M. A.; Vose, A. T.; Birukova, A.; Lewars, K.; Cumming, R. I.; Albright, M. C.; Mark, J. I.; Salazar, C. J.; Swaminathan, S.; Yu, Z.; Sokolenko, Y. V.; Bunyan, E.; Yaeger, M. J.; Fessler, M. B.; Que, L. G.; Gowdy, K. M.; Misharin, A. V.; Tighe, R. M.
10.1101/2023.11.06.565865 — immunology — Posted on 2023-11-06
3759 Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants
Gygi, J. P.; Maguire, C.; Patel, R. K.; Shinde, P.; Konstorum, A.; Shannon, C. P.; Xu, L.; Hoch, A.; Jayavelu, N.; IMPACC Network, ; Haddad, E. K.; Reed, E. F.; Kraft, M.; McComsey, G. A.; Metcalf, J.; Ozonoff, A.; Esserman, D.; Cairns, C. B.; Rouphael, N.; Bosinger, S. E.; Kim-Schulze, S.; Krammer, F.; Rosen, L. B.; Bakel, H.; Wilson, M.; Eckalbar, W.; Maecker, H.; Langelier, C. R.; Steen, H.; Altman, M. C.; Montgomery, R. R.; Levy, O.; Melamed, E.; Pulendran, B.; Arce, J.; Smolen, K. K.; Fragiadakis, G. K.; Becker, P. M.; Augustine, A. D.; Sekaly, R. P.; Ehrlich, L. I. R.; Fourati, S.; Pete
10.1101/2023.11.03.565292 — immunology — Posted on 2023-11-06
3762 Neonatal brain dynamic functional connectivity in term and preterm infants and its association with early childhood neurodevelopment
Franca, L. G. S.; Ciarrusta, J.; Gale-Grant, O.; Fenn-Moltu, S.; Fitzgibbon, S. P.; Chew, A.; Falconer, S.; Dimitrova, R.; Cordero-Grande, L.; Price, A. N.; Hughes, E.; O'Muircheartaigh, J.; Duff, E.; Tuulari, J. J.; Deco, G.; Counsell, S. J.; Hajnal, J. V.; Nosarti, C.; Arichi, T.; Edwards, D.; McAlonan, G.; Batalle, D.
10.1101/2022.11.16.516610 — neuroscience — Posted on 2023-11-06
3764 A modular toolbox for the optogenetic deactivation of transcription
Muench, P.; Fiumara, M.; Southern, N.; Coda, D.; Aschenbrenner, S.; Correia, B.; Graeff, J.; Niopek, D.; Mathony, J.
10.1101/2023.11.06.565805 — synthetic biology — Posted on 2023-11-06
3765 The circulating immune cell landscape stratifies metastatic burden in breast cancer patients
Mangiola, S.; Brown, R.; Berthelet, J.; Guleria, S.; Liyanage, C.; Ostrouska, S.; Wilcox, J.; Merdas, M.; Larsen, P. F.; Bell, C.; Schroder, J.; Mielke, L.; Mariadason, J.; Chang-Hao Tsao, S.; Chen, Y.; Yadav, V. K.; Anderson, R. L.; Vodala, S.; Merino, D.; Behren, A.; Yeo, B.; Papenfuss, T. A.; Pal, B.
10.1101/2023.11.01.565223 — cancer biology — Posted on 2023-11-06
3769 Thermal Stimulus Task fMRI in the Cervical Spinal Cord at 7 Tesla
Seifert, A. C.; Xu, J.; Kong, Y.; Eippert, F.; Miller, K. L.; Tracey, I.; Vannesjo, S. J.
10.1101/2023.01.31.526451 — bioengineering — Posted on 2023-11-06
3771 Comparative transcriptomics reveals the molecular mechanisms of maize in response to downy mildew caused by Peronosclerospora philippinensis (Weston) Shaw
Fernandez, E. C. J.; Simon-Ada, E. V.; Mendoza, J.-v. S.; Manohar, A. N. C.; Gardoce, R. R.; Laude, T. P.; Dela Cueva, F. M.; Lantican, D. V.
10.1101/2023.11.05.565721 — genetics — Posted on 2023-11-06
3773 Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration
Little, A. S.; Younker, I. T.; Schechter, M. S.; Nol Bernardino, P.; Meheust, R.; Stemczynski, J.; Scorza, K.; Mullowney, M. W.; Sharan, D.; Waligurski, E.; Smith, R.; Ramanswamy, R.; Leiter, W.; Moran, D.; McMillin, M.; Odenwald, M. A.; Iavarone, A. T.; Sidebottom, A. M.; Sundararajan, A.; Pamer, E. G.; Eren, A. M.; Light, S. H.
10.1101/2022.12.26.521950 — microbiology — Posted on 2023-11-06
3775 Synergistic anti-phage activity of bacterial defence systems
Wu, Y.; Garushyants, S. K.; van den Hurk, A.; Aparicio-Maldonado, C.; Kushwaha, S. K.; King, C. M.; Ou, Y.; Todeschini, T. C.; Clokie, M. R. J.; Millard, A. M.; Gencay, Y. E.; Koonin, E. V.; Nobrega, F. L.
10.1101/2022.08.21.504612 — microbiology — Posted on 2023-11-06
3778 Evidence for impaired hippocampal circuitry in schizophrenia and its link to memory dysfunction
Zadbood, A.; Tang, Y.; Su, W.; Hu, H.; Capichioni, G.; Yang, S.; Wang, J.; Gasser, C.; Bein, O.; Hui, L.; Jia, Q.; Zhang, T.; Hong, Y.; Wang, J.; Goff, D.; Davachi, L.
10.1101/2023.11.05.565219 — neuroscience — Posted on 2023-11-06
3780 Circadian coupling of mitochondria in a deep-diving mammal
Ciccone, C.; Kante, F.; Folkow, L. P.; Hazlerigg, D.; West, A. C.; Wood, S. H.
10.1101/2023.11.06.565796 — physiology — Posted on 2023-11-06
3782 Behavioral and transcriptomic analyses of mecp2 function in zebrafish
Santistevan, N. J.; Ford, C. T.; Gilsdorf, C. S.; Grinblat, Y. T.
10.1101/2023.09.13.557635 — genetics — Posted on 2023-11-06
3783 Genome-wide ribosome profiling uncovers the role of iron in the control of protein translation
Barlit, H.; Romero, A. M.; Gulhan, A.; Patnaik, P. K.; Tyshkovskiy, A.; Martinez-Pastor, M. T.; Gladyshev, V. N.; Puig, S.; Labunskyy, V.
10.1101/2022.09.22.509115 — genetics — Posted on 2023-11-06
3786 Generation and characterization of Sema6aΔcyt conditional knockout mice
Verhagen, M. G.; van Battum, E. Y.; van den Munkhof, M. H.; Lemstra, S.; Rehberg, K.; van der Meer, C.; van Kronenburg, N. C. H.; Adolfs, Y.; Pasterkamp, R. J.
10.1101/2023.11.06.565851 — developmental biology — Posted on 2023-11-06
3787 Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition
Lozovska, A.; Novoa, A.; Kuo, Y.-Y.; Jurberg, A. D.; Martins, G. G.; Hadjantonakis, A.-K.; Mallo, M.
10.1101/2023.08.22.554351 — developmental biology — Posted on 2023-11-06
3788 Nanometer-scale views of visual cortex reveal anatomical features of primary cilia poised to detect synaptic spillover
Ott, C. M.; Torres, R.; Kuan, T.-S.; Kuan, A. T.; Buchanan, J.; Elabbady, L.; Seshamani, S.; Bodor, A. L.; Collman, F. C.; Bock, D. D.; Lee, W.-C. A.; Macarico da Costa, N.; Lippincott-Schwartz, J.
10.1101/2023.10.31.564838 — cell biology — Posted on 2023-11-06
3789 Identification of a multipotent lung progenitor for lung regeneration
Rosen, C.; Shetzen, E.; Milman -Krentsis, I.; Qi, Y.; Orgad, R.; Su, X.; Yadav, R.; Shemesh, M.; Biram, A.; Shulman, Z.; Eventov-Friedman, S.; Maharjan, M.; Wang, J.; Biton, M.; Reisner, Y.
10.1101/2022.07.07.498730 — cell biology — Posted on 2023-11-06
3791 A modular platform for bioluminescent RNA tracking
Ng, K. K.; Cole, K. H.; Halbers, L. P.; Chan, C. E. T.; Fuller, E. B.; Callicoatte, C.; Metcalfe, M.; Chen, C.; Barhoosh, A. A.; Reid-McLaughlin, E.; Kent, A. D.; Steward, O.; Luptak, A.; Prescher, J. A.
10.1101/2022.07.02.498144 — molecular biology — Posted on 2023-11-06
3792 DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells
Yu, Z.; Sasidharan-Nair, V.; Bonifacius, A.; Khan, F.; Buchta, T.; Beckstette, M.; Niemz, J.; Hilgendorf, P.; Pietzsch, B.; Mausberg, P.; Keller, A.; Falk, C. S.; Busch, D. S.; Brinkmann, M.; Schober, K.; Cicin-Sain, L.; Mueller, F.; Eiz-Vesper, B.; Floess, S.; Huehn, J.
10.1101/2023.11.06.565829 — immunology — Posted on 2023-11-06
3798 Lesions in a songbird vocal circuit increase variability in song syntax
Koparkar, A.; Warren, T. L.; Charlesworth, J. D.; Shin, S.; Brainard, M. S.; Veit, L.
10.1101/2023.07.25.550508 — neuroscience — Posted on 2023-11-06
3800 Combined blockade of CXCR4 and PD-1 enhances intratumoral dendritic cell activation and immune responses against HCC
Morita, S.; Shigeta, K.; Lei, P.; Kobayashi, T.; Kikuchi, H.; Matsui, A.; Huang, P.; Pittet, M.; Duda, D.
10.1101/2023.11.06.564640 — cancer biology — Posted on 2023-11-06
3801 Enzalutamide Induces Cytotoxicity in Desmoplastic Small Round Cell Tumor Independent of the Androgen Receptor
Magrath, J. W.; Goldberg, I. N.; Truong, D. T.; Hartono, A. B.; Sampath, S. S.; Jackson, C. E.; Ghosh, A.; Cardin, D.; Zhang, H.; Ludwig, J.; Lee, S.
10.1101/2023.11.06.565842 — cancer biology — Posted on 2023-11-06
3804 Engineering Modular and Tunable Single Molecule Sensors by Decoupling Sensing from Signal Output
Grabenhorst, L.; Pfeiffer, M.; Schinkel, T.; Kummerlin, M.; Maglic, J. B.; Bruggenthies, G. A.; Selbach, F.; Murr, A. T.; Tinnefeld, P.; Glembockyte, V.
10.1101/2023.11.06.565795 — biophysics — Posted on 2023-11-06
3808 Capturing the blue-light activated state of the Phot-LOV1 domain from Chlamydomonas reinhardtii using time-resolved serial synchrotron crystallography
Gotthard, G.; Mous, S.; Weinert, T.; Maia, R. N. A.; James, D.; Dworkowski, F.; Gashi, D.; Furrer, A.; Ozerov, D.; Panepucci, E.; Wang, M.; Schertler, G. F. X.; Heberle, J.; Standfuss, J.; Nogly, P.
10.1101/2023.11.06.565770 — biochemistry — Posted on 2023-11-06
3813 Bringing TB genomics to the clinic: A comprehensive pipeline to predict antimicrobial susceptibility from genomic data, validated and accredited to ISO standards.
Horan, K.; Viberg, L.; Ballard, S.; Globan, M.; Stevens, K.; Bond, K.; Webb, J.; Dorji, T.; Williamson, D.; Sait, M.; Tay, E. L.; Denholm, J.; Seemann, T.; Howden, B.; Sherry, N.
10.1101/2023.11.04.565651 — genomics — Posted on 2023-11-06
3814 Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species
Mazzamurro, F.; Chirakadavil, J. B.; Durieux, I.; Poire, L.; Plantade, J.; Ginevra, C.; Jarraud, S.; Wilharm, G.; Charpentier, X.; Rocha, E. P. C.
10.1101/2023.11.06.565790 — genomics — Posted on 2023-11-06
3820 coRIC map: a framework for the exploration of multifaceted subcellular RNA-binding proteins
Esteban, M. A.; lv, Y.; Guo, X.; Hu, J.; Kanwal, S.; Yuan, J.; Tariq, M.; Zheng, J.; Sun, M.; Lu, Y.; Wang, J.; Jiang, M.; Wang, A.; Castells-Garcia, A.; Zheng, X.; Peng, B.; Wang, D.; Volpe, G.; Wu, L.; Abdul, M.; Li, W.; Lai, Y.; Aguilo, F.; Zhou, Y.; Cosma, M. P.; Xu, X.; Lundberg, E.; Mulder, J.; Hutchins, A.; Maxwell, P.; Di Croce, L.; Zhang, X.
10.1101/2023.11.06.565240 — cell biology — Posted on 2023-11-06
3821 Myospreader improves gene editing in skeletal muscle by myonuclear propagation
Poukalov, K.; Valero, M. C.; Muscato, D.; Adams, L.; Chun, H.; Lee, Y. i. T.; Andrade, N.; Zeier, Z.; Sweeney, H. L.; Wang, E. T.
10.1101/2023.11.06.565807 — cell biology — Posted on 2023-11-06
3823 Catalytic and non-catalytic functions of DNA polymerase kappa in translesion DNA synthesis
Selles-Baiget, S.; Ambjorn, S. M.; Carli, A.; Hendriks, I. A.; Gallina, I.; Davey, N. E.; Benedict, B.; Meeusen, B.; Hertz, E. P. T.; Slappendel, L.; Semlow, D.; Gadi, S. A.; Sturla, S.; Nielsen, M. L.; Nilsson, J.; Miller, T. C. R.; Duxin, J. P.
10.1101/2023.11.06.565773 — molecular biology — Posted on 2023-11-06
3825 Direct translation of incoming retroviral RNA genomes
Koppke, J.; Keller, L.-E.; Stuck, M.; Arnow, N. D.; Bannert, N.; Doellinger, J.; Cingoz, O.
10.1101/2023.05.02.539066 — microbiology — Posted on 2023-11-06
3826 Prospective Fecal Microbiomics Biomarkers for Chronic Wasting Disease
Didier, A.; Bourner, M.; Kleks, G.; Zolty, A.; Kumar, B.; Nichols, T.; Durynski, K.; Bender, S.; Gibison, M.; Murphy, L.; Ellis, J. C.; Dong, D. W.; Kashina, A.
10.1101/2023.08.21.554213 — microbiology — Posted on 2023-11-06
3827 Induction of immortal-like and functional CAR-T cells by defined factors
Wang, L.; Jin, G.; Zhou, Q.; Liu, Y.; Zhao, X.; Li, Z.; Yin, N.; Peng, M.
10.1101/2023.11.06.565785 — immunology — Posted on 2023-11-06
3828 E-proteins set the threshold for optimal TCF1 expression during αβ T cell development.
Verma, A.; Aylward, B.; Ma, F.; Sherman, C. A.; Chopp, L.; Shinton, S.; Roy, R.; Fahl, S.; Contreras, A.; Koenitzer, B.; Awasthi, P.; Mazan-Mamczarz, K.; De, S.; Ollikainen, N.; Qiu, X.; Bosselut, R.; Sen, R.; Wiest, D.; Sen, J. M.
10.1101/2023.11.06.565822 — immunology — Posted on 2023-11-06
3832 Randomness impacts specific priors building, visual exploration, and perception in object recognition
Gal, C.; Tincas, I.; Moca, V. V.; Ciuparu, A.; Dan, E. L.; Smith, M. L.; Gliga, T.; Muresan, R. C.
10.1101/2023.09.26.559544 — neuroscience — Posted on 2023-11-06
3834 Cytokinin Dehydrogenase in Xylem Sap Reveals A Direct Link Between Cytokinin Metabolism and Long-Distance Transport
Nedved, D.; Motyka, V.; Raimanova, I.; Dobrev, P. I.; Kopecny, D.; Briozzo, P.; Brunoni, F.; Müller, K.; Hoyerova, K.
10.1101/2023.11.06.565614 — plant biology — Posted on 2023-11-06
3835 Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner
Shimonty, A.; Pin, F.; Prideaux, M.; Peng, G.; Huot, J.; Kim, H.; Rosen, C. j.; Spiegelman, B. M.; Bonewald, L. F.
10.1101/2023.11.06.565774 — physiology — Posted on 2023-11-06
3837 A role for cytoglobin in regulating intracellular hydrogen peroxide and redox signals in the vasculature
Mathai, C.; Jourd'heuil, F. L.; Pham, L. G. C.; Gilliard, K.; Balnis, J.; Jen, A.; Overmyer, K. A.; Coon, J. J.; Jaitovich, A.; Boivin, B.; Jourd'heuil, D.
10.1101/2023.03.31.535146 — biochemistry — Posted on 2023-11-06
3838 In vivo silencing of regulatory elements using a single AAV-CRISPRi vector
Laurette, P.; Cao, C.; Ramanujam, D.; Schwaderer, M.; Lueneburg, T.; Kuss, S.; Weiss, L.; Dilshat, R.; Furlong, E. E.; Rezende, F.; Engelhardt, S.; Gilsbach, R.
10.1101/2023.11.05.565512 — genomics — Posted on 2023-11-06
3844 Pioneer factor Pax7 initiates two-step cell-cycle dependent chromatin opening
Gouhier, A.; Dumoulin-Gagnon, J.; Lapointe-Roberge, V.; Harris, J.; Balsalobre, A.; DROUIN, J.
10.1101/2022.11.16.516735 — molecular biology — Posted on 2023-11-06
3845 The Host-specific Microbiota is Required for Diet-Specific Metabolic Homeostasis
Fei, N.; Xie, B.; Long, T. J.; StGeorge, M.; Tan, A.; Manzoor, S.; Sidebottom, A. M.; Melanie Spedale, M.; Betty R Theriault, B. R.; Dinanath Sulakhe, D. S.; B., E. B.
10.1101/2023.11.05.565654 — microbiology — Posted on 2023-11-06
3848 Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells
Wang, J.-P.; Hung, C.-H.; Liou, Y.-H.; Liu, C.-C.; Yeh, K.-H.; Wang, K.-Y.; Lai, Z.-S.; Chatterjee, B.; Hsu, T.-C.; Lee, T.-L.; Shyu, Y.-C.; Hsiao, P.-W.; Chen, L.-Y.; Chuang, T.-J.; Yu, C.-H. A.; Liao, N.-S.; Shen, C.-K. J.
10.1101/2023.04.21.537849 — cancer biology — Posted on 2023-11-06
3855 Touch receptor end-organ innervation and function requires sensory expression of the transcription factor Meis2
Desiderio, S.; Schwaller, F.; Tartour, K.; Padmanabhan, K.; Lewin, G. R.; Carroll, P.; Marmigere, F.
10.1101/2022.04.28.489889 — developmental biology — Posted on 2023-11-06
3856 Molecular dependencies and genomic consequences of a global DNA damage tolerance defect
de Groot, D.; Spanjaard, A.; Shah, R.; Kreft, M.; Morris, B.; Lieftink, C.; Catsman, J. J. I.; Ormel, S.; Ayidah, M.; Pilzecker, B.; Buoninfante, O. A.; van denBerk, P. C. M.; Beijersbergen, R. L.; Jacobs, H.
10.1101/2023.10.11.561854 — molecular biology — Posted on 2023-11-06
3857 Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease
Bhattacharyya, N.; Chai, N.; Hafford-Tear, N. J.; Sadan, A. N.; Szabo, A.; Zarouchlioti, C.; Jedlickova, J.; Leung, S. K.; Liao, T.; Dudakova, L.; Skalicka, P.; Parekh, M.; Moghul, I.; Jeffries, A. R.; Cheetham, M. E.; Muthusamy, K.; Hardcastle, A. J.; Pontikos, N.; Liskova, P.; Tuft, S. J.; Davidson, A. E.
10.1101/2023.03.29.534731 — molecular biology — Posted on 2023-11-06
3858 Novel DNA methylation changes in mouse lungs associated with heavy smoking
Onuzulu, C. D.; Lee, S.; Basu, S.; Comte, J.; Hai, Y.; Hizon, N.; Chadha, S.; Fauni, M. S.; Kahnamoui, S.; Halayko, A. J.; Pascoe, C.; Jones, M. J.
10.1101/2023.11.06.565206 — molecular biology — Posted on 2023-11-06
3860 Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway
Britsch, S.; Koumoundourou, A.; Rannap, M.; De Bruyckere, E.; Nestel, S.; Reissner, C.; Egorov, A.; Liu, P.; Missler, M.; Heimrich, B.; Draguhn, A.
10.1101/2023.05.23.541921 — neuroscience — Posted on 2023-11-06
3863 Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties
Benedetti, M. C.; D'Andrea, T.; Colantoni, A.; Silachev, D.; de Turris, V.; Boussadia, Z.; Babenko, V. A.; Volovikov, E. A.; Belikova, L.; Bogomazova, A. N.; Pepponi, R.; Whye, D.; Buttermore, E. D.; Tartaglia, G. G.; Lagarkova, M. A.; Katanaev, V.; Musayev, I.; Martinelli, S.; Fucile, S.; Rosa, A.
10.1101/2023.06.15.545051 — neuroscience — Posted on 2023-11-06
3864 Host influence on the eukaryotic virome of sympatric mosquitoes and abundance of diverse viruses with a broad host range.
Morel, C.; Gil, P.; Exbrayat, A.; Loire, E.; Charriat, F.; Prepoint, B.; Condachou, C.; Gimonneau, G.; Fall, A. G.; Biteye, B.; Seck, M. T.; Eloit, M.; Gutierrez, S.
10.1101/2023.11.06.565799 — ecology — Posted on 2023-11-06
3865 An Alzheimer's disease-associated common regulatory variant in PTK2B has causal effects on microglial function
Bello, E.; Long, K.; Iwama, S.; Steer, J.; Cooper, S. E.; Alasoo, K.; Kumasaka, N.; Schwartzentruber, J.; Panousis, N. I.; Bassett, A. R.
10.1101/2023.11.04.565613 — neuroscience — Posted on 2023-11-06
3869 Conservation of molecular responses upon viral infection in the non-vascular plant Marchantia polymorpha
Moner-Ross, E.; Jimenez-Gongora, T.; Villar-Martin, L.; Gonzalez-Miguel, V. M.; kutnjak, D.; Rubio-Somoza, I.
10.1101/2023.11.06.565823 — plant biology — Posted on 2023-11-06
3870 BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration
Vargas, J. N. S.; Brown, A.-L.; Sun, K.; Hagemann, C.; Geary, B.; Villarroel-Campos, D.; Bryce-Smith, S.; Zanovello, M.; Lombardo, M.; Ryandov, E.; Stepic, A.; Meysman, L.; Majewski, S.; Tosolini, A.; Secrier, M.; Keuss, M. J.; Serio, A.; Sleigh, J. N.; Fratta, P.; Schiavo, G.
10.1101/2023.11.06.565775 — molecular biology — Posted on 2023-11-06
3872 Dengue virus exploits the host tRNA epitranscriptome to promote viral replication
Chan, C.; Sze, N. S. K.; Suzuki, Y.; Ohira, T.; Suzuki, T.; Begley, T. J.; Dedon, P. C.
10.1101/2023.11.05.565734 — microbiology — Posted on 2023-11-06
3873 Unprecedented spike flexibility revealed by BSL3 Cryo-ET of active SARS-CoV-2 virions
Fukuhara, H.; Dokainish, H. M.; Kita, S.; Tabata, K.; Takasu, A.; Huiskonen, J. T.; Anraku, Y.; Senda, T.; Stuart, D. I.; Sasaki, M.; Orba, Y.; Suzuki, Y.; Sawa, H.; Maenaka, K.
10.1101/2023.10.10.561643 — microbiology — Posted on 2023-11-06
3876 A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus 'fossil record'.
Blanco-Melo, D.; Campbell, M. A.; Zhu, H.; Dennis, T.; Mohda, S.; Lytras, S.; Hughes, J. J.; Gatseva, A.; Gifford, R. J.
10.1101/2023.10.17.562709 — genomics — Posted on 2023-11-06
3878 Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature
Childs, C. J.; Poling, H. M.; Chen, K.; Tsai, Y.-H.; Wu, A.; Sweet, C. W.; Vallie, A.; Eiken, M. K.; Huang, S.; Schreiner, R.; Xiao, Z.; Conchola, A. S.; Anderman, M. F.; Holloway, E. M.; Singh, A.; Giger, R.; Mahe, M. M.; Walton, K. D.; Loebel, C.; Helmrath, M. A.; Rafii, S.; Spence, J. R.
10.1101/2023.11.06.565830 — bioengineering — Posted on 2023-11-06
3880 SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide (CGRP) signaling blockade reduces interleukin 6 (IL-6) release and weight loss in mouse models
Rahman, S. M.; Buchholz, D. W.; Imbiakha, B.; Jaeger, M. C.; Leach, J.; Osborn, R. M.; Birmingham, A. O.; Dewhurst, S.; Aguilar, H. C.; Luebke, A. E.
10.1101/2023.10.23.563669 — neuroscience — Posted on 2023-11-06
3881 JAGGER localization and function is dependent on GPI anchor addition
Figueiredo, R.; Costa, M.; Moreira, D.; Moreira, M.; Noble, J.; Pereira, L. G.; Melo, P.; Palanivelu, R.; Coimbra, S.; Pereira, A. M.
10.1101/2023.11.06.565777 — plant biology — Posted on 2023-11-06
3883 Characterisation and reprogramming of bacteriophage mv4 integrase recombination specificity
Debatisse, K.; Lopez, P.; Poli, M.; Rousseau, P.; Campos, M.; Coddeville, M.; Cocaign-Bousquet, M.; Le Bourgeois, P.
10.1101/2023.11.06.565760 — molecular biology — Posted on 2023-11-06
3884 Multi-night EEG reveals positive association between sleep efficiency and hippocampal subfield volumes in healthy aging
Keresztes, A.; Banko, E.; Bathori, N.; Tomacsek, V.; Varga, V. A.; Narai, A.; Nemecz, Z.; Denes, A.; Gal, V.; Hermann, P.; Simor, P.; Vidnyanszky, Z.
10.1101/2023.11.05.565729 — neuroscience — Posted on 2023-11-06
3885 Nuclear localization of HD-Zip IV transcription factor GLABRA2 is driven byImportin α
Ahmad, B.; Lerma-Reyes, R.; Mukherjee, T.; Nguyen, H. V.; Weber, A. L.; Schulze, W. X.; Comer, J. R.; Schrick, K.
10.1101/2023.11.03.565550 — plant biology — Posted on 2023-11-06
3886 Multi-omics characterization of lymphedema-induced adipose tissue from breast cancer patients
Karaman, S.; Lehti, S.; Zhang, C.; Taskinen, M.-R.; Käkelä, R.; Mardinoglu, A.; Brorson, H.; Alitalo, K. K.; Kivelä, R.
10.1101/2023.11.03.565593 — pathology — Posted on 2023-11-06
3887 Bioenergetic mapping of 'healthy microbiomes' via compound processing potential imprinted in gut and soil metagenomes
Liddicoat, C.; Edwards, R. A.; Roach, M. J.; Robinson, J. M.; Wallace, K. J.; Barnes, A. D.; Brame, J.; Heintz-Buschart, A.; Cavagnaro, T. R.; Dinsdale, E. A.; Doane, M. P.; Eisenhauer, N.; Mitchell, G.; Rai, B.; Ramesh, S.; Breed, M. F.
10.1101/2023.11.05.565728 — bioinformatics — Posted on 2023-11-06
3888 Perpetual bioplastic production by a cyanobacteria-dominated microbiome
Altamira, B.; Arnau Roca, M.; Lage, A.; Gonzalez-Flo, E.; Garcia, J.
10.1101/2023.11.06.565755 — bioengineering — Posted on 2023-11-06
3891 Pathogenic mechanisms underlying adverse neurodevelopmental outcome in congenital heart disease
Gabriel, G. C.; Yagi, H.; Tan, T.; Bais, A. S.; Glennon, B.; Stapleton, M. C.; Huang, L.; Reynolds, W. T.; Shaffer, M. G.; Xu, X.; Ganapathiraju, M.; Simon, D.; Panigrahy, A.; Wu, Y. L.; Lo, C. W.
10.1101/2023.11.05.565716 — developmental biology — Posted on 2023-11-06
3892 Loss of ninein interferes with osteoclast formation and causes premature ossification
Gilbert, T.; Barbier, M.; Duployer, B.; Dufrancais, O.; Martet, L.-E.; Dalbard, E.; Segot, L.; Tenailleau, C.; Verollet, C.; Bierkamp, C.; Merdes, A.
10.1101/2023.11.03.565572 — developmental biology — Posted on 2023-11-06
3893 Non-antibiotic drugs break colonization resistance against pathogenic Gammaproteobacteria
Griesshammer, A.; de la Cuesta-Zuluaga, J.; Zahir, T.; Mueller, P.; Gekeler, C.; Chang, H.; Schmitt, K.; Planker, C.; Bohn, E.; Nguyen, T. H.; Casey Huang, K.; Maier, L.
10.1101/2023.11.06.564936 — microbiology — Posted on 2023-11-06
3894 Impaired updating of working memory representations in individuals with high BMI: evidence for dopaminergic mechanisms
Herzog, N.; Hartmann, H.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.
10.1101/2023.11.03.565528 — neuroscience — Posted on 2023-11-06
3895 Early language experience modulates the cortical tracking of speech
Perez-Navarro, J.; Klimovich-Gray, A.; Lizarazu, M.; Piazza, G.; Molinaro, N.; Lallier, M.
10.1101/2023.09.14.557701 — neuroscience — Posted on 2023-11-06
3898 Potassium stimulates fruit sugar accumulation by increasing carbon flow in Citrus
Kong Jie, W.; Chengxiao, H.; Peiyu, L.; Yinlong, H.; Sun, X.; Qiling, T.; pan, z.; Shoujun, X.; Dong, Z.; Wu, S.
10.1101/2023.11.06.565758 — plant biology — Posted on 2023-11-06
3907 Information-Distilled Generative Label-Free Morphological Profiling Encodes Cellular Heterogeneity
Lo, M. C. K.; Siu, D. M. D.; Lee, K. C. M.; Wong, J. S. J.; Hsin, M. K. Y.; Ho, J. C. M.; Tsia, K. K.
10.1101/2023.11.06.565732 — bioengineering — Posted on 2023-11-06
3908 Relationships of crystallinity and reaction rates for enzymatic degradation of poly (ethylene terephthalate), PET
Schubert, S.; Bach, T. T.; Clausen, K. S.; Malmendal, A.; Hunt, C. J.; Borch, K.; Jensen, K.; Brask, J.; Meyer, A. S.; Westh, P.
10.1101/2023.11.05.564366 — biochemistry — Posted on 2023-11-06
3909 Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of Phosphodiesterase 2A
Delhaye, S.; Jarjat, M.; Boulksibat, A.; Sanchez, C.; Tempio, A.; Turtoi, A.; Giorgi, M.; Lacas-Gervais, S.; Baj, G.; Rovere, C.; Trezza, V.; Pellegrini, M.; Maurin, T.; Lalli, E.; Bardoni, B.
10.1101/2023.11.06.565257 — animal behavior and cognition — Posted on 2023-11-06
3912 Transcriptomics and chromatin accessibility in multiple African population samples
DeGorter, M. K.; Goddard, P. C.; Karakoc, E.; Kundu, S.; Yan, S. M.; Nachun, D. C.; Abell, N.; Aguirre, M.; Carstensen, T.; Chen, Z.; Durrant, M. G.; Dwaracherla, V.; Feng, K.; Gloudemans, M. J.; Hunter, N.; Sathya Moorthy, M. P.; Pomilla, C.; Rodrigues, K. B.; Smith, C. J.; Smith, K. S.; Ungar, R. A.; Balliu, B.; Fellay, J.; Flicek, P.; McLaren, P. J.; Henn, B. M.; McCoy, R. C.; Sugden, L. A.; Kundaje, A.; Sandhu, M. S.; Gurdasani, D.; Montgomery, S. B.
10.1101/2023.11.04.564839 — genomics — Posted on 2023-11-06
3913 Study on genetic differentiation of Schistosome japonicum intermediate hosts Oncomelania hupensis robertsoni in hilly regions of China: using the complete mitochondrial genome
Song, J.; Wang, H.; Li, S.; Zhang, Z.; Li, C.; Zhou, J.; Shen, M.; Qian, P.; Wang, W.; Zhang, Y.; Chen, C.; Wang, L.; Sun, J.; Hao, Y.; Du, C.; Dong, Y.
10.1101/2023.11.05.565742 — genomics — Posted on 2023-11-06
3914 Increasing equity in science requires better ethics training: a course by trainees, for trainees
Patel, R. A.; Ungar, R. A.; Pyke, A. L.; Adimoelja, A.; Chakraborty, M.; Cotter, D. J.; Freund, M.; Goddard, P.; Gomez-Stafford, J.; Greenwald, E.; Higgs, E.; Hunter, N.; MacKenzie, T. M. G.; Narain, A.; Martschenko, D. O.
10.1101/2023.11.03.565577 — genetics — Posted on 2023-11-06
3915 Comparative transcriptomics reveals the molecular mechanisms of maize in response to downy mildew caused by Peronosclerospora philippinensis (Weston) Shaw
Fernandez, E. C. J.; Simon-Ada, E. V.; Mendoza, J.-v. S.; Manohar, A. N. C.; Gardoce, R. R.; Laude, T. P.; Dela Cueva, F. M.; Lantican, D. V.
10.1101/2023.11.05.565721 — genetics — Posted on 2023-11-06
3918 Deciphering mechanisms of UV filter- and temperature-induced bleaching in the coral Acropora tenuis, using ecotoxicogenomics
Nishioka, S.; Miyata, K.; Inoue, Y.; Aoyama, K.; Yoshioka, Y.; Miura, N.; Yamane, M.; Honda, H.; Takagi, T.
10.1101/2023.11.05.564681 — ecology — Posted on 2023-11-06
3921 Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic Reprograming
Yadav, S.; Ganta, V.; Sudhahar, V.; Ash, D.; Nagarkoti, S.; Das, A.; McMenamin, M.; Kelley, S.; Fukai, T.; Ushio-Fukai, M.
10.1101/2023.11.04.565656 — cell biology — Posted on 2023-11-06
3923 CTRP7 as a Molecular Biomarker for Predicting Responsiveness to Pulmonary Vasodilators: Insights from Human and Animal Studies in Pulmonary Arterial Hypertension
Yamada, K.; Satoh, T.; Yaoita, N.; Miyamichi-Yamamoto, S.; Sato, H.; Yamada, Y.; Komaru, K.; Chiba, N.; Nakata, T.; Nochioka, K.; Oishi, H.; Miyata, S.; Okada, Y.; Yasuda, S.
10.1101/2023.11.05.565725 — molecular biology — Posted on 2023-11-06
3925 The modified RNA base acp3U is an attachment site for N-glycans in glycoRNA
Xie, Y.; Hemberger, H.; Till, N. A.; Chai, P.; Watkins, C.; Lebedenko, C. G.; Caldwell, R. M.; George, B.; Bertozzi, C. R.; Garcia, B. A.; Flynn, R. A.
10.1101/2023.11.06.565735 — molecular biology — Posted on 2023-11-06
3926 From sequence to ecology: siderophore-receptor coevolution algorithm predicts bacterial interactions in complex communities
Gu, S.; Shao, Z.; Shao, Y.; Zhu, S.; Zhang, D.; Allen, R.; He, R.; Shao, J.; Xiong, G.; Qu, Z.; Jousset, A.; Friman, V.-P.; Wei, Z.; Kuemmerli, R.; Li, Z.
10.1101/2023.11.05.565711 — microbiology — Posted on 2023-11-06
3927 A biophysically constrained brain connectivity model based on stimulation-evoked potentials.
Schmid, W.; Danstrom, I.; Crespo Echevarria, M.; Adkinson, J.; Mattar, L.; Banks, G.; Sheth, S.; Watrous, A. J.; Heilbronner, S. R.; Bijanki, K.; Alabastri, A.; Bartoli, E.
10.1101/2023.11.03.565525 — neuroscience — Posted on 2023-11-06
3930 Polymer Implantable Electrode Foundry: A shared resource for manufacturing polymer-based microelectrodes for neural interfaces
Scholten, K.; Xu, H.; Lu, Z.; Jiang, W.; Ortigoza-Diaz, J.; Petrossians, A.; Orler, S.; Gallonio, R.; Liu, X.; Song, D.; Meng, E.
10.1101/2023.11.05.565048 — neuroscience — Posted on 2023-11-06
3935 Linking the gut microbiome to host DNA methylation by a discovery and replication epigenome-wide association study
Demirkan, A.; van Dongen, J.; Finnicum, C.; Westra, H. J.; Jankipersadsing, S.; Willemsen, G.; Ijzerman, R.; Boomsma, D.; Ehli, E.; Bonder, M. J.; Fu, J.; Franke, L.; Wijmenga, C.; de Geus, E.; Kurilshikov, A.; Zhernakova, A.
10.1101/2023.11.03.565420 — genomics — Posted on 2023-11-06
3936 Ubiquitination-mediated Golgi-to-endosome sorting determines the toxin-antidote duality of wtf meiotic drivers
Zheng, J.-X.; Du, T.-Y.; Shao, G.-C.; Ma, Z.-H.; Jiang, Z.-D.; Hu, W.; Suo, F.; He, W.; Dong, M.-Q.; Du, L.-L.
10.1101/2023.07.15.549172 — cell biology — Posted on 2023-11-06
3940 From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways
Gu, S.; Shao, Y.; Rehm, K.; Bigler, L.; Zhang, D.; He, R.; Shao, J.; Jousset, A.; Friman, V.-P.; Wei, Z.; Kummerli, R.; Li, Z.
10.1101/2023.10.30.564663 — genomics — Posted on 2023-11-06
3942 Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Yao, J.; Dai, S.; Zhu, R.; Tan, J.; Zhao, Q.; Yin, Y.; Sun, J.; Du, X.; Ge, L.; Xu, J.; Hou, C.; Li, N.; Li, J.; Ji, W.; Zhu, C.; Zhang, R.; Li, T.
10.1101/2023.05.15.540723 — neuroscience — Posted on 2023-11-06
3943 Multi-Scale Spiking Network Model of Human Cerebral Cortex
Pronold, J.; van Meegen, A.; Vollenbroeker, H.; Shimoura, R.; Senden, M.; Hilgetag, C.; Bakker, R.; van Albada, S.
10.1101/2023.03.23.533968 — neuroscience — Posted on 2023-11-05
3945 Polycomb Repressive Complex 2 is critical for mouse cortical glutamatergic neuron development
Currey, L. E.; Mitchell, B.; Al-Kahlily, M.; McElnea, S.-J.; Harkins, D.; Pelenyi, A.; Kurniawan, N.; Burne, T. E.; Harris, L.; Thor, S.; Piper, M.
10.1101/2023.11.05.565413 — developmental biology — Posted on 2023-11-05
3946 Atlas of Fshr Expression from Novel Reporter Mice
Chen, H.-Q.; Fang, H.; Liu, J.-T.; Chang, S.-Y.; Cheng, L.-B.; Sun, M.-X.; Feng, J.-R.; Liu, Z.; Zhang, Y.; Zaidi, M.; J. Rosen, C.; Liu, P.
10.1101/2023.11.05.565707 — cell biology — Posted on 2023-11-05
3949 Bulky glycocalyx drives cancer invasiveness by modulating substrate-specific adhesion
Barai, A.; Piplani, N.; Gomathi, V.; Ghogale, M. M.; Kumar, S.; Kulkarni, M.; Sen, S.
10.1101/2023.08.03.551677 — cancer biology — Posted on 2023-11-05
3950 Linking modulation of bio-molecular phase behaviour with collective interactions
Qian, D.; Ausserwoger, H.; Arter, W. E.; Scrutton, R.; Welsh, T. J.; Kartanas, T.; Ermann, N.; Qamar, S.; Fischer, C.; Sneideris, T.; St George-Hyslop, P.; Pappu, R. V.; Knowles, T.
10.1101/2023.11.02.565376 — biophysics — Posted on 2023-11-05
3951 Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex
Pinotsis, N.; Krüger, A.; Tomas, N.; Chatziefthymiou, S. D.; Litz, C.; Mortensen, S. A.; Daffe, M.; Marrakchi, H.; Antranikian, G.; Wilmanns, M.
10.1101/2022.04.07.487456 — biochemistry — Posted on 2023-11-05
3954 Multi-Step Cellular Control of Molecular Condensation by Microtubules in Early Oogenesis
Deis, R.; Kar, S.; Ahmad, A.; Bogoch, Y.; Dominitz, A.; Shvaizer, G.; Sasson, E.; Mytlis, A.; Ben-Zvi, A.; Elkouby, Y. M.
10.1101/2022.03.11.484019 — developmental biology — Posted on 2023-11-05
3955 An EpCAM/Trop2 mechanostat differentially regulates individual and collective behaviour of human carcinoma cells
Aslemarz, A.; Fagotto-Kaufmann, M.; Ruppel, A.; Fagotto-Kaufmann, C.; Balland, M.; Lasko, P.; Fagotto, F.
10.1101/2022.10.03.510449 — cell biology — Posted on 2023-11-05
3958 Emergence of disease-specific endothelial and stromal cell populations responsible for arterial remodeling during development of pulmonary arterial hypertension
Cober, N. D.; McCourt, E.; Soares Godoy, R.; Deng, Y.; Schlosser, K.; Situ, A.; Cook, D. P.; Lemay, S.-E.; Klouda, T.; Yuan, K.; Bonnet, S.; Stewart, D. J.
10.1101/2023.09.06.555321 — molecular biology — Posted on 2023-11-05
3960 A WIDESPREAD PICORNAVIRUS AFFECTS THE HAEMOCYTES OF THE NOBLE PEN SHELL (PINNA NOBILIS) LEADING TO IMMUNOSUPPRESSION
Carella, F.; Prado, P.; De Vico, G.; Palic, D.; Villari, G.; Garcia-March, J. R.; Tena-Mediadea, J.; Melendreras, E. C.; Gimenez-Casalduero, F.; Sigovini, M.; Aceto, S.
10.1101/2023.11.05.565683 — pathology — Posted on 2023-11-05
3963 Phenogenomic resources immortalized in a panel of wild-derived strains of five species of house mice
Pialek, J.; Dureje, L.; Hiadlovska, Z.; Kreisinger, J.; Aghova, T.; Bryjova, A.; Cizkova, D.; Gouy de Bellocq, J.; Hejlova, H.; Janotova, K.; Martincova, I.; Orth, A.; Pialkova, J.; Pospisilova, I.; Rouskova, L.; Bimova, B. V.; Bonhomme, F.; Forejt, J.; Macholan, M.; Klusackova, P.
10.1101/2023.11.05.565684 — evolutionary biology — Posted on 2023-11-05
3964 The highly abundant mRNA m1A modification: a new layer of gene regulation in dinoflagellates
LI, C.; LI, Y.; GUO, J.; WANG, Y.; SHI, X.; ZHANG, Y.; LIANG, N.; YUAN, J.; XU, J.; Chen, H.
10.1101/2023.11.04.565600 — molecular biology — Posted on 2023-11-05
3965 Sex- and age-dependent effects of locus coeruleus-originated tau dysfunction on olfaction and neurophysiology in rats
Dutton, O. D. E.; Wasef, M. A.; Burke, A. T.; Chirinos, E. A.; Jones, A. T.; Vey, R.; Skinner, D. M.; Harley, C. W.; Walling, S. G.
10.1101/2023.11.05.565692 — neuroscience — Posted on 2023-11-05
3969 Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer
Saatci, O.; Alam, R.; Huynh-Dam, K.-T.; Isik, A.; Uner, M.; Belder, N.; Ersan, P. G.; Cetin, M.; Tokat, U. M.; Gedik, M. E.; Bal, H.; Sahin, O. S.; Riazalhosseini, Y.; Thieffry, D.; Gautheret, D.; Ogretmen, B.; Aksoy, S.; Uner, A.; Akyol, A.; Sahin, O.
10.1101/2023.11.05.565697 — cancer biology — Posted on 2023-11-05
3970 Anesthetic oxygen use and sex are critical factors in the FLASH sparing effect
Tavakkoli, A. D.; Clark, M. A.; Kheirollah, A.; Sloop, A. M.; Soderholm, H. E.; Daniel, N. J.; Petusseau, A. F.; Huang, Y. H.; Thomas, C. R.; Jarvis, L. A.; Zhang, R.; Pogue, B. W.; Gladstone, D. J.; Hoopes, P. J.
10.1101/2023.11.04.565626 — cancer biology — Posted on 2023-11-05
3972 Movi: a fast and cache-efficient full-text pangenome index
Zakeri, M.; Brown, N. K.; Ahmed, O. Y.; Gagie, T.; Langmead, B.
10.1101/2023.11.04.565615 — bioinformatics — Posted on 2023-11-05
3974 Zinc stimulation of coastal productivity in low carbon dioxide environments
Kell, R. M.; Subhas, A. V.; Schanke, N. L.; Lees, L. E.; Chmiel, R. J.; Rao, D.; Brisbin, M. M. M.; Moran, D. M.; McIlvin, M. R.; Bolinesi, F.; Mangoni, O.; Casotti, R.; Balestra, C.; Horner, T.; Dunbar, R. B.; Allen, A. E.; DiTullio, G. R.; Saito, M. A.
10.1101/2023.11.05.565706 — biochemistry — Posted on 2023-11-05
3975 An intronic copy number variation in Syntaxin 17 determines speed of greying and melanoma incidence in Grey horses
Andersson, L.; Rubin, C.-J.; Hodge, M.; Naboulsi, R.; Beckman, M.; Bellone, R. R.; Kallenberg, A.; Usrey, S. J.; Ohmura, H.; Seki, K.; Ohnuma, A.; Davis, B. W.; Tozaki, T.; Lindgren, G.
10.1101/2023.11.05.565619 — genetics — Posted on 2023-11-05
3976 Whole Genome Sequencing and Assembly of the House Sparrow, Passer domesticus
Kumar, V.; Sharma, G.; Sharma, S.; Vishnudasan, D.; Maheswaran, G.; Tyagi, K.; Tyagi, I.; PB, K. K.; Chaubey, G.; Suravajhala, P.
10.1101/2023.11.04.565608 — evolutionary biology — Posted on 2023-11-05
3977 The changing morphology of the ventricular walls of mouse and human with increasing gestation.
Jensen, B.; Chang, Y. H.; Bamforth, S. D.; Mohun, T.; Sedmera, D.; Bartos, M.; Anderson, R. H.
10.1101/2023.11.05.565685 — developmental biology — Posted on 2023-11-05
3978 Proteolytic degradation of atrial sarcomere proteins underlies contractile defects in atrial fibrillation
Cizauskas, H.; Burnham, H.; Panni, A.; Pena, A.; Alvarez-Arce, A.; Davis, M. T.; Araujo, K.; Delligatti, C.; Edaserry, S.; Kirk, J.; Arora, R.; Barefield, D.
10.1101/2023.11.05.565691 — cell biology — Posted on 2023-11-05
3981 Contexts facilitate dynamic value encoding in the mesolimbic dopamine system
Fraser, K. M.; Collins, V. L.; Wolff, A. R.; Ottenheimer, D. J.; Bornhoft, K. N.; Pat, F.; Chen, B. J.; Janak, P. H.; Saunders, B. T.
10.1101/2023.11.05.565687 — neuroscience — Posted on 2023-11-05
3985 Renal mechanotransduction is an essential regulator of renin
Hill, R. Z.; Shirvan, S.; Burquez, S.; Dubin, A. E.; Servin Vences, M. R.; Miner, J. H.; Patapoutian, A.
10.1101/2023.11.04.565646 — physiology — Posted on 2023-11-05
3991 FICTURE: Scalable segmentation-free analysis of sub-micron resolution spatial transcriptomics
Si, Y.; Lee, C.; Hwang, Y.; Yun, J. H.; Cheng, W.; Cho, C.-S.; Quiros, M.; Nusrat, A.; Zhang, W.; Jun, G.; Zoellner, S.; Lee, J. H.; Kang, H. M.
10.1101/2023.11.04.565621 — bioinformatics — Posted on 2023-11-05
3992 An injectable in situ crosslinkable platform for ultra-long-acting delivery of hydrophilic therapeutics
Lee, S.; Zhao, S.; Chen, X.; Zhu, L.; Joseph, J.; Agus, E.; Barooj, S.; Mary, H. B.; Shah, P.; Slaughter, K.; Cheung, K.; Luo, J. N.; Gao, J.; Lee, D.; Karp, J.; Joshi, N.
10.1101/2023.11.04.565631 — bioengineering — Posted on 2023-11-05
3993 Electric fields determine carbapenemase activity in class A β-lactamases
Jabeen, H.; Beer, M.; Spencer, J.; van der Kamp, M. W.; Bunzel, H. A.; Mulholland, A. J.
10.1101/2023.11.04.565607 — biochemistry — Posted on 2023-11-05
3996 A blood-brain-barrier penetrant AAV gene therapy rescues neurological deficits in mucolipidosis IV mice.
Sangster, M.; Bishop, M.; Yao, Y.; Feitor, J. F.; Shahriar, S.; Miller, M.; Chekuri, A.; Budnik, B.; Bei, F.; Grishchuk, Y.
10.1101/2023.11.03.565568 — genetics — Posted on 2023-11-05
3998 Swimming with the current improves juvenile survival in southern elephant seals
Foo, D.; McMahon, C. R.; Hindell, M. A.; Fedak, M.; Biuw, M.; McConnell, B.; Raymond, B.
10.1101/2023.11.05.565668 — ecology — Posted on 2023-11-05
3999 VAV2-DEPENDENT REGULATION OF RIBOSOME BIOGENESIS IN KERATINOCYTES AND ORAL SQUAMOUS CELL CARCINOMA
Fernandez-Parejo, N.; Lorenzo-Martin, L. F.; Garcia-Pedrero, J. M.; Rodrigo, J. P.; Dosil, M.; Bustelo, X. R.
10.1101/2023.11.03.565464 — cancer biology — Posted on 2023-11-05
4002 Whole genome sequencing analysis identifies rare, large-effect non-coding variants and regions associated with circulating protein levels
Hawkes, G.; Chundru, K.; Jackson, L.; Patel, K. A.; Murray, A.; Wood, A. R.; Wright, C. R.; Weedon, M. N.; Frayling, T. M.; Beaumont, R. N.
10.1101/2023.11.04.565589 — genetics — Posted on 2023-11-05
4004 A High-Throughput Data-Independent Acquisition Workflow for Deep Characterisation of the sn-Isomer Lipidome
Michael, J. A.; Young, R. S. E.; Balez, R.; Jekimovs, L. J.; Marshall, D. L.; Poad, B. L. J.; Mitchell, T. W.; Blanksby, S. J.; Ejsing, C. S.; Ellis, S. R.
10.1101/2023.11.04.565044 — cell biology — Posted on 2023-11-05
4005 Heterogeneity in Neutrophil Extracellular Traps from Healthy Human Subjects
Collins, M. S.; Imbrogno, M. A.; Kopras, E. J.; Howard, J. A.; Zhang, N.; Kramer, E. L.; Hudock, K. M.
10.1101/2023.11.03.565547 — cell biology — Posted on 2023-11-05
4006 The feature landscape of visual cortex
Tong, R.; da Silva, R.; Lin, D.; Ghosh, A.; Wilsenach, J.; Cianfarano, E.; Bashivan, P.; Richards, B.; Trenholm, S.
10.1101/2023.11.03.565500 — neuroscience — Posted on 2023-11-05
4008 PANAMA enabled high sensitivity dual nanoflow LC/MS metabolomics and proteomics analysis
Lin, W.; Mousavi, F. M.; Blum, B. C.; Heckendorf, C. F.; Lampl, N.; Heckman, R.; Guo, H.; McComb, M.; Emili, A.
10.1101/2023.11.03.565531 — systems biology — Posted on 2023-11-05
4011 Single-nucleus transcriptomics of epicardial adipose tissue from females reveals exercise control of innate and adaptive immune cells
Ahmad, I.; Gupta, S. C.; Faulkner, P.; Mullens, D.; Thomas, M.; Sytha, S. P.; Ivanov, I.; Cai, J. J.; Heaps, C. L.; Newell-Fugate, A. E.
10.1101/2023.11.02.565385 — physiology — Posted on 2023-11-05
4012 Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)
Zhang, T.; Ambrodji, A.; Huang, H.; Bouchonville, K. J.; Etheridge, A. S.; Schmidt, R. E.; Bembenek, B. M.; Temesgen, Z. B.; Wang, Z.; Innocenti, F.; Stroka, D.; Diasio, R. B.; Largiader, C. R.; Offer, S.
10.1101/2023.11.01.565230 — pharmacology and toxicology — Posted on 2023-11-05
4014 The in vitro dynamics of pseudo-vascular network formation.
Oraiopoulou, M.-E.; Couturier, D.-L.; Bunce, E. V.; Cannell, I.; Golinska, M.; Hannon, G. J.; Sakkalis, V.; Bohndiek, S. E.
10.1101/2023.11.02.565264 — cancer biology — Posted on 2023-11-05
4018 Protein Engineering with Lightweight Graph Denoising Neural Networks
Zhou, B.; Zheng, L.; Wu, B.; Tan, Y.; Lv, O.; Yi, K.; Fan, G.; Hong, L.
10.1101/2023.11.05.565665 — bioengineering — Posted on 2023-11-05
4019 Identification of Small Molecule Ligand Binding Sites On and In the ARNT PAS-B Domain
Xu, X.; Marcelino, L. P.; Favaro, D. C.; Silvestrini, M. L.; Solazzo, R.; Chong, L. T.; Gardner, K. H.
10.1101/2023.11.03.565595 — biochemistry — Posted on 2023-11-05
4022 Experimental evolution of multicellularity via cuboidal cell packing in fission yeast
Pineau, R.; Kahn, P. C.; Lac, D. T.; Denning, M.; Wong, W.; Ratcliff, W.; Bozdag, G. O.
10.1101/2023.11.03.565576 — evolutionary biology — Posted on 2023-11-05
4027 Egg MVBs elicit an antimicrobial pathway to degrade paternal mitochondria after fertilization
Ben-Hur, S.; Afar, S.; Politi, Y.; Gal, L.; Golani, O.; Sivan, E.; Haffner-Krausz, R.; Maizenberg, E.; Peretz, S.; Roth, Z.; Kalo, D.; Dezorella, N.; Morgenstern, D.; Pietrokovski, S.; Yacobi-Sharon, K.; Arama, E.
10.1101/2023.11.05.565307 — developmental biology — Posted on 2023-11-05
4028 Targeting cellular cathepsins inhibits hepatitis E virus infection
Kloehn, M.; Burkard, T.; Janzen, J.; Schrader, J. A.; Goemer, A.; Brown, R. J. P.; Dao Thi, V. L.; Kinast, V.; Brueggemann, Y.; Todt, D.; Steinmann, E.
10.1101/2023.11.03.565430 — cell biology — Posted on 2023-11-05
4033 Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats
Amen, A.; Yoo, R.; Fabra-Garcia, A.; Bolscher, J.; Stone, W. J. R.; Bally, I.; Dergan-Dylon, S.; Kucharska, I.; de Jong, R. M.; de Bruijni, M.; Bousema, T.; King, C. R.; MacGill, R. S.; Sauerwein, R. W.; Julien, J.-P.; Poignard, P.; Jore, M. M.
10.1101/2023.11.03.565335 — immunology — Posted on 2023-11-05
4034 Interleukin-10-producing monocytes contribute to sex differences in pain resolution in mice and humans.
Sim, J.; O'Guin, E.; Monahan, K.; Sugimoto, C.; McLean, S.; Albertorio-Saez, L.; Zhao, Y.; Dagenais, A.; Laumet, S.; Bernard, M.; Folger, J. K.; Robison, A. J.; Linnstaedt, S. D.; Laumet, G.
10.1101/2023.11.03.565129 — immunology — Posted on 2023-11-05
4035 PARP knockdown promotes synapse reformation after axon injury
Belew, M. Y.; Huang, W.; Florman, J. T.; Alkema, M. J.; Byrne, A. B.
10.1101/2023.11.03.565562 — neuroscience — Posted on 2023-11-05
4037 Rapid nongenomic estrogen signaling controls alcohol drinking behavior
Zallar, L. J.; Rivera-Irizarry, J. K.; Hamor, P. U.; Pigulevskiy, I.; Liu, D.; Welday, J. P.; Rico Rozo, A.-S.; Bender, R.; Asfouri, J.; Skelly, M. J.; Fecteau, K. M.; Hadley, C. K.; Levine, O. B.; Mehanna, H.; Nelson, S.; Miller, J.; Ghazal, P.; Bellotti, P.; Erikson, D. W.; Geri, J.; Pleil, K. E.
10.1101/2023.11.02.565358 — neuroscience — Posted on 2023-11-05
4040 Preclinical lentiviral vector-mediated hematopoietic stem and progenitor cell gene therapy corrects Pompe disease-related muscle and neurological manifestations
Yoon, J. K.; Schindler, J. W.; Loperfido, M.; Baricordi, C.; DeAndrade, M. P.; Jacobs, M. E.; Treleaven, C.; Plasschaert, R. N.; Yan, A.; Barese, C. N.; Dogan, Y.; Chen, V. P.; Fiorini, C.; Hull, F.; Barbarossa, L.; Unnisa, Z.; Ivanov, D.; Kutner, R. H.; Guda, S.; Oborski, C.; Maiwald, T.; Michaud, V.; Rothe, M.; Schambach, A.; Pfeifer, R.; Mason, C.; Biasco, L.; van Til, N. P.
10.1101/2023.11.03.565442 — neuroscience — Posted on 2023-11-05
4041 Male-male interactions shape mate selection in Drosophila
Hindmarsh Sten, T.; Li, R.; Hollunder, F.; Eleazer, S.; Ruta, V.
10.1101/2023.11.03.565582 — neuroscience — Posted on 2023-11-05
4042 Dual long-axis reorganization of hippocampus in youth
Zeng, D.; Li, Q.; Li, D.; He, Y.; Dong, X.; Li, S.; Bi, S.; Liao, X.; Zhao, T.; Chen, X.; Xia, Y.; Lei, T.; Sun, L.; Men, W.; Wang, Y.; Wang, D.; Hu, M.; Pan, Z.; Tan, S.; Gao, J.-H.; Qin, S.; Tao, S.; Dong, Q.; He, Y.; Zuo, X.; Li, S.
10.1101/2023.11.03.565423 — neuroscience — Posted on 2023-11-05
4044 The evolutionary conserved choroid plexus sustains the homeostasis of brain ventricles in zebrafish
Jeong, I.; Andreassen, S. N.; Hoang, L.; Poulain, M.; Seo, Y.; Park, H.-C.; Fürthauer, M.; MacAulay, N.; Jurisch-Yaksi, N.
10.1101/2023.11.03.565468 — neuroscience — Posted on 2023-11-05
4047 Limitations of line-scan MRI for directly measuring neural activity
Wilson, J. M.; Wu, H.; Kerr, A. B.; Wandell, B. A.; Gardner, J. L.
10.1101/2023.11.03.565394 — neuroscience — Posted on 2023-11-05
4048 Electrophysiological analyses of human dorsal root ganglia and human induced pluripotent stem cell-derived sensory neurons from male and female donors
Zurek, N. A.; Ehsanian, R.; Goins, A. E.; Adams, I. M.; Petersen, T.; Goyal, S.; Shilling, M.; Westlund, K. N.; Alles, S. R.
10.1101/2023.11.03.565343 — neuroscience — Posted on 2023-11-05
4049 A high-performance brain-sentence communication designed for logosyllabic language
Feng, C.; Cao, L.; Wu, D.; Zhang, E.; Wang, T.; Jiang, X.; Ding, H.; Zhou, C.; Chen, J.; Wu, H.; Lin, S.; Hou, Q.; Zhu, J.; Yang, J.; Sawan, M.; Zhang, Y.
10.1101/2023.11.05.562313 — neuroscience — Posted on 2023-11-05
4051 Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury
Wang, Y.; Halawani, D.; Estill, M.; Ramakrishnan, A.; Shen, L.; Friedel, R. H.; Zou, H.
10.1101/2023.11.04.565649 — neuroscience — Posted on 2023-11-05
4054 Flood-irrigated agriculture mediates climate-induced wetland scarcity for summering sandhill cranes in western North America
Donnelly, J. P.; Collins, D. P.; Knetter, J. M.; Gammonley, J. H.; Boggie, M. A.; Grisham, B. A.; Nowak, C. M.; Naugle, D. E.
10.1101/2023.11.03.565509 — systems biology — Posted on 2023-11-05
4055 Multimodal single cell-resolved spatial proteomics reveals pancreatic tumor heterogeneity
Xu, Y.; Wang, X.; Li, Y.; Mao, Y.; Su, Y.; Yang, Y.; Gao, W.; Fu, C.; Chen, W.; Ye, X.; Liang, F.; Bai, P.; Sun, Y.; Xu, R.; Tian, R.
10.1101/2023.11.04.565590 — systems biology — Posted on 2023-11-05
4056 The use of bacterial consortia improves seed tuber production in potato varieties for frying
Contreras-Liza, S.; Mauricio Ramirez, R.; Rodriguez Grados, P.; Quiliche, J. P.; Montemayor Mantilla, J.; Palomares Anselmo, E.
10.1101/2023.11.02.565409 — plant biology — Posted on 2023-11-05
4057 Pseudomonas syringae infectivity correlates to altered transcript and metabolite levels of Arabidopsis Mediator mutants
Blomberg, J.; Tasselius, V.; Vergara, A.; Karamat, F.; Imran, Q. M.; Strand, A.; Rosvall, M.; Björklund, S.
10.1101/2023.11.03.565469 — plant biology — Posted on 2023-11-05
4060 Discovery of a Novel Chemotype as DYRK1A Inhibitors against Alzheimer's disease: Computational Modeling and Biological Evaluation
Qiu, N.; Qian, C.; Guo, T.; Wang, Y.; Jin, H.; Yao, M.; Li, M.; Guo, T.; Lv, Y.; Si, X.; Wu, S.; Wang, H.; Zhang, X.; Xia, J.
10.1101/2023.11.03.565431 — pharmacology and toxicology — Posted on 2023-11-05
4061 Utilizing gene co-expression networks with the rat kidney TXG-MAPr tool to enhance safety assessment, biomarker identification and human translation
Kunnen, S. J.; Callegaro, G.; Sutherland, J. J.; Trairatphisan, P.; Wijaya, L. S.; van Kessel, H.; Chung, G.; Pye, K.; Brown, C.; Goldstein, K. M.; Teague, C. R.; Fisher, C.; Harvey, J. S.; Elmore, S. A.; Heinz-Taheny, K. M.; Stevens, J. L.; van de Water, B.
10.1101/2023.11.03.565444 — pharmacology and toxicology — Posted on 2023-11-05
4063 PAH DEFICIENT PATHOLOGY IN HUMANIZED c.1066-11G>A PHENYLKETONURIA MICE
Martinez-Pizarro, A.; Pico, S.; Lopez-Marquez, A.; Rodriguez-Lopez, C.; Montalvo, E.; Alvarez, M.; Castro, M.; Ramon-Maiques, S.; Perez, B.; Lucas, J. J.; Richard, E. M.; Desviat, L. R.
10.1101/2023.11.03.565447 — pathology — Posted on 2023-11-05
4064 Proteomics of Patient-derived Breast Tumours Identifies a Pro-migratory Osteomodulin-Cyclin Dependent Kinase 1 Axis which Drives Bone Metastasis
Parsons, J.; Harrison, H.; Kedward, T.; Fullwood, P.; Cabral, S.; Spence, K.; Barden, D.; Haworth, J.; Watson, J.; Tsafou, K.; Behan, C.; Ali, N.; Smith, M.; O'Brien, C.; Clarke, R.; Francavilla, C.
10.1101/2023.11.03.565489 — cancer biology — Posted on 2023-11-05
4065 MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation
Guerin, C. M.; Vinchent, A.; Damour, I.; Laratte, A.; Tellier, R.; Estevam, G.; Meneboo, J.-P.; Villenet, C.; Descarpentries, C.; Fraser, J. S.; Figeac, M.; Cortot, A. B.; Rouleau, E.; Tulasne, D.
10.1101/2023.11.03.565283 — cancer biology — Posted on 2023-11-05
4069 Linking modulation of bio-molecular phase behaviour with collective interactions
Qian, D.; Ausserwoger, H.; Arter, W. E.; Scrutton, R.; Welsh, T. J.; Kartanas, T.; Ermann, N.; Qamar, S.; Fischer, C.; Sneideris, T.; St George-Hyslop, P.; Pappu, R. V.; Knowles, T.
10.1101/2023.11.02.565376 — biophysics — Posted on 2023-11-05
4072 Integrating single-cell RNA-seq datasets with substantial batch effects
Hrovatin, K.; Moinfar, A. A.; Tejada Lapuerta, A.; Zappia, L.; Lengerich, B.; Kellis, M.; Theis, F. J.
10.1101/2023.11.03.565463 — bioinformatics — Posted on 2023-11-05
4075 HiCMC: High-Efficiency Contact Matrix Compressor
Adhisantoso, Y. G.; Korner, T.; Muntefering, F.; Ostermann, J.; Voges, J.
10.1101/2023.11.03.565487 — bioinformatics — Posted on 2023-11-05
4077 HiTIPS: High-Throughput Image Processing Software for the Study of Nuclear Architecture and Gene Expression
Keikhosravi, A.; Almansour, F.; Bohrer, C. H.; Fursova, N. A.; Guin, K.; Sood, V.; Misteli, T.; Larson, D. R.; Pegoraro, G.
10.1101/2023.11.02.565366 — bioinformatics — Posted on 2023-11-05
4079 Machine learning-based exploration, expansion and definition of the atropopeptide family of ribosomally synthesized and posttranslationally modified peptides
Biermann, F.; Tan, B.; Breitenbach, M.; Nanudorn, P.; Dimitrova, Y.; Kakumu, Y.; Walker, A. S.; Ueoka, R.; Helfrich, E. J. N.
10.1101/2023.11.03.565440 — bioinformatics — Posted on 2023-11-05
4082 DNA Origami Vesicle Sensors with Triggered Cargo Transfer
Buber, E.; Yaadav, R.; Schroeder, T.; Franquelim, H. G.; Tinnefeld, P.
10.1101/2023.11.03.565475 — bioengineering — Posted on 2023-11-05
4088 NAD+ controls circadian rhythmicity during cardiac aging
Carpenter, B. J.; Lecacheur, M.; Mangold, Y. N.; Cui, K.; Guenther, S.; Dierickx, P.
10.1101/2023.11.02.565150 — genomics — Posted on 2023-11-05
4089 An integrated single-cell reference atlas of the human endometrium
Mareckova, M.; Garcia-Alonso, L.; Moullet, M.; Lorenzi, V.; Petryszak, R.; Sancho-Serra, C.; Oszlanczi, A.; Icoresi Mazzeo, C.; Hoffman, S.; Krassowski, M.; Garbutt, K.; Kelava, I.; Gaitskell, K.; Yancheva, S.; Von Woon, E.; Male, V.; Granne, I.; Hellner, K.; Mahbubani, K. T.; Saeb-Parsy, K.; Lotfollahi, M.; Prigmore, E.; Southcombe, J.; Dragovic, R. A.; Becker, C. M.; Zondervan, K. T.; Vento-Tormo, R.
10.1101/2023.11.03.564728 — genomics — Posted on 2023-11-05
4090 Genomic structures and regulation patterns at HPV integration sites in cervical cancer
Porter, V. L.; O'Neill, K.; MacLennan, S.; Corbett, R. D.; Ng, M.; Culibrk, L.; Hamadeh, Z.; Iden, M.; Schmidt, R.; Tsaih, S.-W.; Chang, G.; Fan, J.; Nip, K. M.; Akbari, V.; Chan, S. K.; Hopkins, J.; Moore, R. A.; Chuah, E.; Mungall, K. L.; Mungall, A. J.; Birol, I.; Jones, S. J. M.; Rader, J. S.; Marra, M. A.
10.1101/2023.11.04.564800 — genomics — Posted on 2023-11-05
4093 Pseudotime analysis for time-series single-cell sequencing and imaging data
Li, G.; Kim, H.-J.; Pendyala, S.; Zhang, R.; Disteche, C. M.; Vert, J.-P.; Deng, X.; Fowler, D.; Noble, W. S.
10.1101/2023.11.03.565575 — genomics — Posted on 2023-11-05
4094 link-ancestors: Fast simulation of local ancestry with tree sequence software
Tsambos, G.; Kelleher, J.; Ralph, P. L.; Leslie, S. J.; Vukcevic, D.
10.1101/2023.11.03.564476 — genomics — Posted on 2023-11-05
4095 Generation of human induced pluripotent stem cell (hiPSC) lines from patients with extreme high and low polygenic scores for QT interval
Mitchell, D.; Ullah, R.; Vanags, L.; Shen, A.; Jones, L.; O'Neill, M.; Davogustto, G.; Shaffer, C.; Roden, D.; Shoemaker, B.; Williams, H.; Strickland, T.; Agee, T.; Johnson, C.; Kroncke, B.
10.1101/2023.11.03.565486 — genetics — Posted on 2023-11-05
4100 Disturbance-generated competitive coexistence
Trigos-Raczkowski, U. A.; Lyons, R.; Delgadino, M. G.; Ackleh, A. S.; Ostling, A.
10.1101/2023.11.02.565332 — ecology — Posted on 2023-11-05
4103 Global Biogeography of the Soil Virosphere
Graham, E. B.; Camargo, A. P.; Wu, R.; Neches, R. Y.; Nolan, M.; Paez-Espino, D.; Copeland, A.; Kyrpides, N.; Jansson, J. K. K.; McDermott, J. E.; Hofmockel, K. S.; Soil Virosphere Consortium,
10.1101/2023.11.02.565391 — ecology — Posted on 2023-11-05
4104 Molecular Forecasting of Domoic Acid during a Pervasive Toxic Diatom Bloom
Brunson, J. K.; Thukral, M.; Ryan, J. P.; Anderson, C. R.; Kolody, B. C.; James, C. C.; Chavez, F. P.; Leaw, C. P.; Rabines, A. J.; Venepally, P.; Zheng, H.; Kudela, R. M.; Smith, G. J.; Moore, B. S.; Allen, A. E.
10.1101/2023.11.02.565333 — ecology — Posted on 2023-11-05
4106 Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
Bruter, A. V.; Varlamova, E. A.; Stavskaya, N. I.; Antysheva, Z. G.; Manskikh, V. N.; Tvorogova, A. V.; Korshunova, D. S.; Khamidullina, A. I.; Utkina, M. V.; Bogdanov, V. P.; Nikiforova, A. I.; Albert, E. A.; Maksimov, D. O.; Li, J.; Chen, M.; Shtil, A. A.; Roninson, I. B.; Mogila, V. A.; Silaeva, Y. Y.; Tatarskiy, V. V.
10.1101/2023.11.04.564913 — developmental biology — Posted on 2023-11-05
4107 Heterozygous missense variant in GLI2 impairs human endocrine pancreas development
Mueller, L. M.; Isaacson, A.; Wilson, H.; Salowka, A.; Gong, M.; Raile, K.; Spagnoli, F. M.
10.1101/2023.11.05.565673 — developmental biology — Posted on 2023-11-05
4109 Reevaluating the Concept of Aging: Long-Term Stress Adaptation as a Key Factor in Yeast Aging
Kong, Y.; Adejoro, D.; Winefield, C.; On, S.; Wescombe, P. A.; Subbaraj, A.; Saunders, A.; Chelikani, V.
10.1101/2023.11.03.565426 — cell biology — Posted on 2023-11-05
4110 RudLOV-a new optically synchronized cargo transport method reveals unexpected effect of dynasore
Tago, T.; Ogawa, T.; Goto, Y.; Toyooka, K.; Tojima, T.; Nakano, A.; Satoh, T.; Satoh, A. K.
10.1101/2023.11.04.565648 — cell biology — Posted on 2023-11-05
4117 Haptenic adducts of beta-lactam antibiotics elicit antibody responses with narrow clonality and specificity
Deimel, L. P.; Moynie, L.; Sun, G.; Lewis, V.; Turner, A.; Buchanan, C. J.; Burnap, S. A.; Kobras, C. M.; Stracy, M.; Struwe, W. B.; Baldwin, A. J.; Naismith, J.; Davis, B. G.; Sattentau, Q. J.
10.1101/2023.11.02.565155 — immunology — Posted on 2023-11-05
4119 Intracranial tumors elicit systemic sympathetic hyperactivity that limits immunotherapeutic responses
Lorrey, S. J.; Wachsmuth, L.; Finlay, J.; Waibl Polania, J.; Hoyt-Miggelbrink, A.; Price, M.; Neff, C.; Cui, X.; Hawley, A.; Lerner, E.; Wilkinson, D.; Srinivasan, E.; Ostrom, Q. T.; Fecci, P. E.
10.1101/2023.11.02.565368 — immunology — Posted on 2023-11-05
4120 Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Zaire ebolavirus, Sudan ebolavirus, Marburg and Lassa viruses
Flaxman, A.; Sebastian, S.; Appelberg, S.; Cha, K.; Ulaszewska, M.; Purushotham, J.; Gilbride, C.; Sharpe, H.; Spencer, A.; Bibi, S.; Wright, D.; Dowall, S.; Easterbrook, L.; Findlay-Wilson, S.; Gilbert, S.; Mirazimi, A.; Lambe, T.
10.1101/2023.11.03.565549 — immunology — Posted on 2023-11-05
4122 Active-like structure of the ligand-binding domain of GluK2 with L-glutamate and the positive allosteric modulator BPAM344
Bay, Y.; Jeppesen, M. E.; Frydenvang, K.; Francotte, P.; Pirotte, B.; Pickering, D. S.; Kristensen, A. S.; Kastrup, J. S.
10.1101/2023.11.02.565309 — neuroscience — Posted on 2023-11-05
4123 Brain Charts for People Living with Multiple Sclerosis
Keshavan, A.; Peterson, D.; Alexander-Bloch, A.; Leyden, K.
10.1101/2023.11.02.565251 — neuroscience — Posted on 2023-11-05
4124 Human Endogenous Retrovirus Expression is Dynamically Regulated in Parkinson's Disease
Gordevicius, J.; Goralski, T.; Bergsma, A.; Parham, A.; Kuhn, E.; Meyerdirk, L.; McDonald, M.; Milciute, M.; Putten, E. V.; Marshall, L.; Brundin, P.; Brundin, L.; Labrie, V.; Henderson, M.; Pospisilik, J. A.
10.1101/2023.11.03.565438 — neuroscience — Posted on 2023-11-05
4125 Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators
Francotte, P.; Bay, Y.; Goffin, E.; Colson, T.; Lesenfants, C.; Dorosz, J.; Laulumaa, S.; Fraikin, P.; de Tullio, P.; Beaufour, C.; Botez, I.; Pickering, D. S.; Frydenvang, K.; Danober, L.; Kristensen, A. S.; Kastrup, J. S.; Pirotte, B.
10.1101/2023.11.02.565294 — neuroscience — Posted on 2023-11-05
4126 Sex-Dependent Genetic Expression Signatures within Cocaine- and Sucrose-Seeking Ensembles in Mice
Litif, C. G.; Flom, L. T.; Sandum, K. L.; Hodgins, S. L.; Vaccaro, L.; Stitzel, J. A.; Blouin, N. A.; Mannino, M. C.; Gigley, J. P.; Schoborg, T.; Bobadilla, A.-C.
10.1101/2023.11.02.565378 — neuroscience — Posted on 2023-11-05
4128 Assessment of extracellular vesicle protein cargo as neurodegenerative disease biomarkers
Gilboa, T.; Ter-Ovanesyan, D.; Wang, S.-C.; Whiteman, S.; Kannarkat, G. T.; Church, G. M.; Chen-Plotkin, A. S.; Walt, D. R.
10.1101/2023.11.02.565137 — neuroscience — Posted on 2023-11-05
4130 Microscale visualization of cellular features in adult macaque visual cortex
Balaram, P.; Takasaki, K. T.; Hellevik, A.; Tandukar, J.; Turschak, E.; MacLennan, B.; Ouellette, N.; Torres, R.; Laughland, C.; Gliko, O.; Seshamani, S.; Perlman, E.; Taormina, M.; Peterson, E.; Juneau, Z.; Potekhina, L.; Glaser, A.; Chandrashekar, J.; Logsdon, M.; Cao, K.; Dylla, C.; Hatanaka, G.; Chatterjee, S.; Ting, J. T.; Vumbaco, D.; Waters, J. T.; Bair, W.; Tsao, D.; Gao, R.; Reid, R. C.
10.1101/2023.11.02.565381 — neuroscience — Posted on 2023-11-05
4132 Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538
Bay, Y.; Fransen, S. M.; Pickering, D. S.; Frydenvang, K.; Francotte, P.; Pirotte, B.; Kristensen, A. S.; Kastrup, J. S.
10.1101/2023.11.02.565302 — neuroscience — Posted on 2023-11-05
4133 Connectome-Based Attractor Dynamics Guide Brain Activity in Rest, Task, and Disease
Englert, R.; Kincses, B.; Kotikalapudi, R.; Gallitto, G.; Li, J.; Hoffschlag, K.; Woo, C.-W.; Wager, T.; Timmann, D.; Bingel, U.; Spisak, T.
10.1101/2023.11.03.565516 — neuroscience — Posted on 2023-11-05
4135 Deep learning-based synaptic event detection
O'Neill, P. S.; Baccino-Calace, M.; Rupprecht, P.; Friedrich, R. W.; Mueller, M.; Delvendahl, I.
10.1101/2023.11.02.565316 — neuroscience — Posted on 2023-11-05
4137 The hepatocyte Epidermal Growth Factor Receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche
Gonzalez-Sanchez, E.; Vaquero, J.; Caballero-Diaz, D.; Grzelak, J.; Fuste, N. P.; Bertran, E.; Amengual, J.; Garcia-Saez, J.; Martin-Mur, B.; Gut, M.; Esteve-Codina, A.; Alay, A.; Coulouarn, C.; Calero, S.; Valdecantos, P.; Valverde, A. M.; Sanchez, A.; Herrera, B.; Fabregat, I.
10.1101/2023.11.03.565317 — pathology — Posted on 2023-11-05
4139 ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation
Coleman, O. I.; Sorbie, A.; Bierwirth, S.; Koevilein, J.; von Stern, M.; Koehler, N.; Wirbel, J.; Schmidt, C.; Kacprowski, T.; Dunkel, A.; Pauling, J. K.; Plagge, J.; Miedel-Cuadra, D.; Wagner, S.; Peng, T.; Metzler, T.; Schafmayer, C.; Hinz, S.; Roeder, C.; Roecken, C.; Stecher, B.; Rosenstiel, P.; Steiger, K.; Jesinghaus, M.; Liebisch, G.; Ecker, J.; Zeller, G.; Janssen, K.-P.; Haller, D.
10.1101/2023.11.03.565267 — cancer biology — Posted on 2023-11-05
4144 Predmoter - Cross-species prediction of plant promoter and enhancer regions
Kindel, F.; Triesch, S.; Schlueter, U.; Randarevitch, L. A.; Reichel-Deland, V.; Weber, A.; Denton, A. K.
10.1101/2023.11.03.565452 — bioinformatics — Posted on 2023-11-05
4146 Mosquito virus diversity in Western and North-western Uganda
Mayanja, M. N.; Niebel, M.; Ashraf, S.; Hardy, M.; Ssekagiri, A.; Tong, L.; Nantezza, A.; Matovu, E.; Nyakaana, S.; Filipe, A. D. S.; Mwiine, F.; Lutwama, J.; Thomson, E. C.
10.1101/2023.11.02.565349 — genomics — Posted on 2023-11-05
4152 Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
Lasolle, H.; Schiavo, A. A.; Tourneur, A.; Gillotay, P.; da Fonseca, B. d. F.; Ceolin, L.; Monestier, O.; Aganahi, B.; Chomette, L.; Kizys, M. M. L.; Haenebalcke, L.; Pieters, T.; Goossens, S.; Haigh, J.; Detours, V.; Maia, A. L.; Costagliola, S.; Romitti, M.
10.1101/2023.03.30.534915 — cancer biology — Posted on 2023-11-05
4153 Sources of gene expression variation in a globally diverse human cohort
Taylor, D. J.; Chhetri, S. B.; Biddanda, A.; Tassia, M. G.; Battle, A.; McCoy, R. C.
10.1101/2023.11.04.565639 — genomics — Posted on 2023-11-05
4154 Common evolutionary origins of the bacterial glycyl tRNA synthetase and alanyl tRNA synthetase
Alvarez-Carreno, C.; Arciniega, M.; Ribas de Pouplana, L.; Petrov, A. S.; Hernandez-Gonzalez, A.; Valencia-Sanchez, M. I.; Williams, L. D.; Torres-Larios, A.
10.1101/2023.05.29.542759 — evolutionary biology — Posted on 2023-11-05
4159 Sources of gene expression variation in a globally diverse human cohort
Taylor, D. J.; Chhetri, S. B.; Biddanda, A.; Tassia, M. G.; Battle, A.; McCoy, R. C.
10.1101/2023.11.04.565639 — genomics — Posted on 2023-11-05
4162 Precision-Cut Liver Slices as an ex vivo model to evaluate antifibrotic therapies for liver fibrosis and cirrhosis
Wang, Y.; Leaker, B.; Qiao, G.; Sojoodi, M.; Eissa, I. R.; Epstein, E. T.; Eddy, J.; Dimowo, O.; Lauer, G. M.; Chung, R. T.; Qadan, M.; Lanuti, M.; Fuchs, B. C.; Tanabe, K. K.
10.1101/2023.10.30.564772 — cell biology — Posted on 2023-11-05
4163 Gut microbiota promotes enteroendocrine cell maturation and mitochondrial function
Alsudayri, A.; Perelman, S.; Chura, A.; Brewer, M.; McDevitt, M.; Drerup, C.; Ye, L.
10.1101/2023.09.27.558332 — cell biology — Posted on 2023-11-05
4164 Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury
Eisdorfer, J. T.; Thackray, J. K.; Theis, T.; Vivinetto, A.; Ricci, M. T.; Lin, S.; Oputa, O.; Martinez, A. M.; Nacht, H. D.; Tschang, M.; Mahmood, M.; Tucker, A.; Bohic, M.; Pusuloori, S.; Zmoyro, L.; Abraira Lab Computational Group, ; Popovich, P.; Ferguson, A. R.; McTigue, D.; Tysseling, V. M.; Dulin, J.; Hollis, E.; Datta, S. R.; Abraira, V. E. G.
10.1101/2023.10.31.564826 — neuroscience — Posted on 2023-11-05
4167 Real-time Quantification of in vivo cerebrospinal fluid velocity using fMRI inflow effect
Diorio, T. C.; Vijayakrishnan Nair, V.; Patel, N.; Hedges, L. E.; Rayz, V. L.; Tong, Y.
10.1101/2023.08.14.553250 — physiology — Posted on 2023-11-05
4170 The roles of DDR2 and substrate stiffness on cancer cell transcriptome and proliferation
Vessella, T.; Xiang, S.; Xiao, C.; Stilwell, M.; Rozen, E.; Shohet, J.; Zhou, S.; Wen, Q.
10.1101/2023.10.29.564363 — biochemistry — Posted on 2023-11-05
4172 Perturb-tracing enables high-content screening of multiscale 3D genome regulators
Cheng, Y.; Hu, M.; Yang, B.; Jensen, T. B.; Yang, T.; Yu, R.; Ma, Z.; Radda, J. S. D.; Jin, S.; Zang, C.; Wang, S.
10.1101/2023.01.31.525983 — genetics — Posted on 2023-11-05
4173 Benefits and Limits of Phasing Alleles for Network Inference of Allopolyploid Complexes
Tiley, G. P.; Crowl, A. A.; Manos, P. S.; Sessa, E. B.; Solis-Lemus, C.; Yoder, A. D.; Burleigh, J. G.
10.1101/2021.05.04.442457 — evolutionary biology — Posted on 2023-11-05
4175 A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
Abassah-Oppong, S.; Mannion, B.; Zoia, M.; Rouco, R.; Tissieres, V.; Spurrell, C.; Roland, V.; Darbellay, F.; Ljubojevic, A.; Gamart, J.; Festa, T. A.; Sullivan, C. S.; Rodriguez-Carballo, E.; Fukuda-Yuzawa, Y.; Hunter, R. D.; Novak, C. S.; Plajzer-Frick, I.; Tran, S.; Akiyama, J. A.; Dickel, D. E.; Lopez-Rios, J.; Barozzi, I.; Andrey, G.; Visel, A.; Pennacchio, L. A.; Cobb, J.; Osterwalder, M.
10.1101/2020.11.22.393173 — developmental biology — Posted on 2023-11-05
4177 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Liegeois, F.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-11-05
4178 Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria
Novak, L. V. F.; Treitli, S. C.; Pyrih, J.; Hałakuc, P.; Pipaliya, S. V.; Vacek, V.; Brzon, O.; Soukal, P.; Eme, L.; Dacks, J. B.; Karnkowska, A.; Elias, M.; Hampl, V.
10.1101/2022.11.24.517819 — microbiology — Posted on 2023-11-05
4181 Tonically active GABAergic neurons in the dorsal periaqueductal gray control the initiation and execution of instinctive escape
Stempel, A. V.; Evans, D. A.; Pavon Arocas, O.; Claudi, F.; Lenzi, S. C.; Kutsarova, E.; Margrie, T. W.; Branco, T.
10.1101/2023.11.03.565561 — neuroscience — Posted on 2023-11-05
4182 Immunoproximity biotinylation reveals the axon initial segment proteome
Zhang, W.; Fu, Y.; Peng, L.; Ogawa, Y.; Ding, X.; Rasband, A.; Zhou, X.; Shelly, M.; Rasband, M. N.; Zou, P.
10.1101/2023.03.06.531334 — neuroscience — Posted on 2023-11-05
4184 Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
Johnson, J. A. I.; Stein-O'Brien, G. L.; Booth, M.; Heiland, R.; Kurtoglu, F.; Bergman, D.; Bucher, E.; Deshpande, A.; Forjaz, A.; Getz, M.; Godet, I.; Lyman, M.; Metzcar, J.; Mitchell, J.; Raddatz, A.; Rocha, H. L.; Solorzano, J.; Sundus, A.; Wang, Y.; Gilkes, D. M.; Kagohara, L. T.; Kiemen, A. L.; Thompson, E. D.; Wirtz, D.; Wu, P.-H.; Zaidi, N.; Zheng, L.; Zimmerman, J. W.; Jaffee, E. M.; Chang, Y. H.; Coussens, L.; Gray, J.; Heiser, L. M.; Fertig, E. J.; Macklin, P.
10.1101/2023.09.17.557982 — systems biology — Posted on 2023-11-05
4185 Sida cordifolia, a medicinal plant is efficacious in models of Huntingtons disease, by reducing ER stress
Simha, P. K.; Mukherjee, C.; Gupta, V. K. G. K.; Sapariya, N. M.; Nagar, P.; Nazeer, A.; Godbole, A.; Sahu, B. S.; Upadhyay, S.
10.1101/2023.11.01.565080 — pharmacology and toxicology — Posted on 2023-11-05
4186 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting
Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.
10.1101/2022.06.23.497372 — bioengineering — Posted on 2023-11-05
4188 Thiolutin has complex effects in vivo but is a direct inhibitor of RNA Polymerase II in vitro
Qiu, C.; Arora, P.; Malik, I.; Laperuta, A. J.; Pavlovic, E. M.; Ugochukwu, S.; Naik, M. T.; Kaplan, C. D.
10.1101/2021.05.05.442806 — molecular biology — Posted on 2023-11-05
4189 A Cellular Basis for Mapping Behavioural Structure
El-Gaby, M.; Harris, A. L.; Whittington, J. C.; Dorrell, W.; Bhomick, A.; Walton, M. W.; Akam, T.; Behrens, T. E.
10.1101/2023.11.04.565609 — neuroscience — Posted on 2023-11-05
4190 Sources of gene expression variation in a globally diverse cohort
Taylor, D. J.; Chhetri, S. B.; Biddanda, A.; Tassia, M. G.; Battle, A.; McCoy, R. C.
10.1101/2023.11.04.565639 — genomics — Posted on 2023-11-05
4192 Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus
Rasetto, N. B.; Giacomini, D.; Berardino, A. A.; Vega Waichman, T.; Beckel, M. S.; Di Bella, D. J.; Brown, J.; Davies-Sala, M. G.; Gerhardinger, C.; Lie, D. C.; Arlotta, P.; Chernomoretz, A.; Schinder, A. F.
10.1101/2023.11.03.565477 — neuroscience — Posted on 2023-11-05
4195 Using compartmental models to understand excitation-inhibition imbalance in epilepsy
Kamaraj, A. K.; Szuromi, M. P.; Galvis, D.; Stacey, W. C.; Skeldon, A. C.; Terry, J. R.
10.1101/2023.11.03.565450 — neuroscience — Posted on 2023-11-05
4196 Protein migration and topography mapping reveals endogenous protein processing and homomers in Nicotiana benthamiana.
Zheng, K.; Lyu, J.; Thomas, E.; Schuster, M.; Sanguankiattichai, N.; Kaschani, F.; Kaiser, M.; van der Hoorn, R. A. L.
10.1101/2023.11.02.565301 — plant biology — Posted on 2023-11-04
4198 Short-term Pre-operative Methionine Restriction Induces Browning of Perivascular Adipose Tissue and Improves Vein Graft Remodeling in Mice
Kip, P.; Sluiter, T. J.; MacArthur, M. R.; Tao, M.; Jung, J.; Mitchell, S. J.; Kooijman, S.; Kruit, N.; Gorham, J.; Seidman, J.; Quax, P. H. A.; Aikawa, M.; Ozaki, C. K.; Mitchell, J. R.; De Vries, M. R.
10.1101/2023.11.02.565269 — systems biology — Posted on 2023-11-04
4203 Unveiling the Microbial Diversity and Associated Secondary Metabolism on Black Apples
Cowled, M. S.; Phippen, C. B. W.; Kromphardt, K. J. K.; Clemmensen, S. E.; Frandsen, R.; Frisvad, J. C.; Larsen, T. O.
10.1101/2023.11.02.565319 — ecology — Posted on 2023-11-04
4205 Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling
Alvarez, S.; Gupta, S.; Honeychurch, K.; Mercado-Ayon, Y.; Kawaguchi, R.; Butler, S. J.
10.1101/2023.11.02.565384 — developmental biology — Posted on 2023-11-04
4207 Candida albicans suppression of neutrophil reactive nitrogen species is rescued by host Hif-1alpha in vivo
Burgess, T. B.; Hammond, F. R.; Szkuta, P. T.; Lewis, A.; Christou, S.; Ayscough, K. R.; Johnston, S. A.; Condliffe, A. M.; Elks, P. M.
10.1101/2023.11.02.565128 — immunology — Posted on 2023-11-04
4209 Cannabinoid receptor type 2 expression in mouse brain: from mapping to regulation in microglia under inflammatory conditions
Grabon, W.; Ruiz, A.; Gasmi, N.; Degletagne, C.; Georges, B.; Belmeguenai, A.; Bodennec, J.; Rheims, S.; Marcy, G.; Bezin, L.
10.1101/2023.11.02.565330 — neuroscience — Posted on 2023-11-04
4210 Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation
Zollner, H. J.; Davies-Jenkins, C. B.; Simicic, D. B.; Tal, A.; Sulam, J.; Oeltzschner, G.
10.1101/2023.11.01.565164 — neuroscience — Posted on 2023-11-04
4211 LEAFY interacts with WHEAT ORTHOLOG OF APO1 to regulate spikelet number per spike in wheat
Paraiso, F.; Zhang, J.; Lin, H.; Li, C.; Woods, D. P.; Lan, T.; Debernardi, J. M.; Joe, A.; Dubcovsky, J.
10.1101/2023.11.02.565263 — plant biology — Posted on 2023-11-04
4212 Molecular subtypes of high grade serous ovarian cancer across racial groups and gene expression platforms
Davidson, N. R.; Barnard, M. E.; Hippen, A. A.; Campbell, A.; Johnson, C.; Way, G. P.; Dalley, B. K.; Berchuck, A.; Salas, L. A.; Peres, L. C.; Marks, J. R.; Schildkraut, J. M.; Greene, C. S.; Doherty, J. A.
10.1101/2023.11.01.565179 — cancer biology — Posted on 2023-11-04
4214 Pre-existing Subclones Determine Radioresistance in Rectal Cancer Organoids
Andel, D.; Viergever, B.; Peters, N.; Raats, D.; van Schelven, S.; Intven, M.; Zandvliet, M.; Hagendoorn, J.; Borel Rinkes, I.; Kranenburg, O.
10.1101/2023.11.02.565315 — cancer biology — Posted on 2023-11-04
4215 Planar Amorphous Silicon Carbide Microelectrode Arrays for Chronic Recording in Rat Motor Cortex
Abbott, J. R.; Jeakle, E. N.; Haghihi, P.; Usoro, J. O.; Sturgill, B. S.; Wu, Y.; Geramifard, N.; Radhakrishna, R.; Patnaik, S.; Nakajima, S.; Hess, J.; Mehmood, Y.; Devata, V.; Vijayakumar, G.; Sood, A.; Thai, T. T. D.; Dogra, K.; Hernandez-Reynoso, A. G.; Pancrazio, J. J.; Cogan, S. F.
10.1101/2023.11.02.565338 — bioengineering — Posted on 2023-11-04
4220 H3K9me regulates heterochromatin silencing through incoherent feedforward loops
Yabe, K.; Asuka, K.; Oya, S.; Kakutani, T.; Hirayama, M.; Tanaka, Y.; Inagaki, S.
10.1101/2023.11.02.565278 — genetics — Posted on 2023-11-04
4223 Microbial abundance and diversity in 64-74 Ma subseafloor igneous basement from the Louisville Seamount Chain
Sylvan, J. B.; Tully, B. J.; Morono, Y.; Alt, J. C.; Grim, S. L.; Inagaki, F.; Koppers, A. A.; Edwards, K. J.
10.1101/2023.11.02.565174 — ecology — Posted on 2023-11-04
4225 AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
Houston, B. J.; Nguyen, J.; Merriner, D. J.; O'Connor, A. E.; Lopes, A. M.; Nagirnaja, L.; Friedrich, C.; Kliesch, S.; Tuettelmann, F.; Aston, K. I.; Conrad, D.; Hobbs, R. M.; Dunleavy, J. E.; O'Bryan, M. K.
10.1101/2023.11.02.565050 — cell biology — Posted on 2023-11-04
4226 Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1
Dans, M. G.; Boulet, C.; Watson, G. M.; Nguyen, W.; Dziekan, J. M.; Evelyn, C.; Reaksudsan, K.; Mehra, S.; Razook, Z.; Geoghegan, N. D.; Mlodzianoski, M. J.; Goodman, C. D.; Ling, D. B.; Jonsdottir, T. K.; Tong, J.; Famodimu, M. T.; Kouskousis, B.; Delves, M. J.; McFadden, G. I.; Barry, A. E.; Crabb, B. S.; de Koning-Ward, T. F.; Rogers, K.; Cowman, A. F.; Tham, W.-H.; Sleebs, B. E.; Gilson, P. R.
10.1101/2023.11.02.565411 — cell biology — Posted on 2023-11-04
4227 A novel exopolysaccharide pathway from a freshwater Sphingomonas isolate
Goetsch, A. G.; Ufearo, D.; Keiser, G.; Heiss, C.; Azadi, P.; Hershey, D. M.
10.1101/2023.11.03.565537 — microbiology — Posted on 2023-11-04
4229 Traitor-virus-guided discovery of novel antiviral factors
Prelli Bozzo, C.; Laliberte, A.; De Luna, A.; Pastorio, C.; Regensburger, K.; Krebs, S.; Graf, A.; Blum, H.; Volcic, M.; Sparrer, K. M.; Kirchhoff, F.
10.1101/2023.11.03.565501 — microbiology — Posted on 2023-11-04
4231 High temporal frequency light response in mouse retina is mediated by ON and OFF bipolar cells and requires FAT3 signaling
Aviles, E. C.; Wang, S. K.; Patel, S.; Shi, S.; Lin, L.; Kefalov, V.; Goodrich, L.; Cepko, C.; Xue, Y.
10.1101/2023.11.02.565326 — neuroscience — Posted on 2023-11-04
4232 LOSS OF CLDN5 -AND INCREASE IN IRF7- IN THE HIPPOCAMPUS AND CEREBRAL CORTEX OF DIABETIC MICE AT THE EARLY SYMPTOMATIC STAGE.
Carus-Cadavieco, M.; Gonzalez de la Fuente, S.; Berenguer, I.; Serrano-Lope, M. A.; Aguado, B.; Palomer, E.; Guix, F.; Dotti, C. G.
10.1101/2023.11.02.565280 — neuroscience — Posted on 2023-11-04
4233 Chemical inhibition of stomatal differentiation by perturbation of the master-regulatory bHLH heterodimer via an ACT-Like domain
Nakagawa, A.; Sepuru, K. M.; Yip, S. J. A.; Seo, H.; Coffin, C. M.; Segawa, Y.; Iwasaki, R.; Kato, H.; Kim, S.; Aihara, Y.; Kinoshita, T.; Itami, K.; Han, S.-K.; Murakami, K.; Torii, K. U.
10.1101/2023.11.02.565226 — plant biology — Posted on 2023-11-04
4234 Genotype combinations drive variability in the microbiome configuration of the rhizosphere of Maize/Bean intercropping system
Lanzavecchia, G.; Frascarelli, G.; Rocchetti, L.; Bellucci, E.; Bitocchi, E.; Di Vittori, V.; Sillo, F.; Ferraris, I.; Carta, G.; Delledonne, M.; Nanni, L.; Papa, R.
10.1101/2023.11.02.564926 — plant biology — Posted on 2023-11-04
4235 Lac-Phe mediates the anti-obesity effect of metformin
Xiao, S.; Li, V. L.; Lyu, X.; Chen, X.; Wei, W.; Abbasi, F.; Knowles, J.; Deng, S.; Tiwari, G.; Shi, X.; Deng, S.; Farrell, L.; Chen, Z.-Z.; Taylor, K.; Guo, X.; Goodarzi, M.; Wood, A.; Chen, Y.-D. I.; Lange, L.; Rich, S. S.; Rotter, J.; Clish, C. B.; Tahir, U.; Gerszten, R. E.; Benson, M.; Long, J. Z.
10.1101/2023.11.02.565321 — physiology — Posted on 2023-11-04
4237 Feeding Behavior Modifies Daily Rhythms in Autonomic Signaling and Core Body Temperature to Shape 24-hour Rhythms in Cardiac Electrophysiology
Ono, M.; Burgess, D.; Johnson, S. R.; Elayi, C. S.; Esser, K. A.; Seward, T. S.; Boychuk, C. A.; Stalcup, R. A.; Prabhat, A.; Schroder, E.; Delisle, B. P.
10.1101/2023.11.02.565372 — physiology — Posted on 2023-11-04
4238 Activation of the mechanistic target of rapamycin complex 1 (mTORC1) in thyrocytes induces follicular hyperplasia and impairs thyroid hormone synthesis
Rossetti, C. L.; Lourenconi, B.; Pecanha, F. L. M.; Nose, V.; Lew, J.; Carneiro, E.; Bernal-Mizrachi, E.; Werneck de Castro, J. P.
10.1101/2023.11.01.565171 — physiology — Posted on 2023-11-04
4239 Butyrate-producing bacteria as probiotic supplement: beneficial effects on metabolism and modulation of behavior in an obesity mouse model
Garcia-Serrano, A. M.; Skoug, C.; Axling, U.; Korhonen, E. R.; Teixeira, C.; Lazou Ahren, I.; Mukhopadhya, I.; Boteva, N.; Martin, J.; Scott, K.; Gratz, S.; Stenkula, K. G.; Holm, C.; Duarte, J. M. N.
10.1101/2023.11.02.564919 — physiology — Posted on 2023-11-04
4240 Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo.
Varache, M.; Rizzo, S.; Sayers, E. J.; Newbury, L.; Mason, A.; Liao, C.-T.; Chiron, E.; Bourdiec, N.; Jones, A.; Fraser, D. J.; Taylor, P. R.; Jones, A. T.; Thomas, D. W.; Ferguson, E. L.
10.1101/2023.11.02.565265 — pharmacology and toxicology — Posted on 2023-11-04
4241 Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma
Yang, J.; Lim, J. T.; Santiago Raj, P. V.; Chen, C.; Khawaja, H.; Schnellmann, R. G.; Roe, D. J.; Gokhale, P. C.; DeCaprio, J. A.; Padi, M.
10.1101/2023.11.01.565218 — cancer biology — Posted on 2023-11-04
4242 HPV and p53 status as precision determinants of head and neck cancer response to DNA-PKcs inhibition in combination with irradiation
Hayrapetyan, L.; Roth, S. M.; Hovhannisyan, L.; Medo, M.; Quintin, A.; Ott, J.; Albers, J.; Aebersold, D. M.; Zimmer, Y.; Medova, M.
10.1101/2023.11.02.565300 — cancer biology — Posted on 2023-11-04
4243 Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity
Kugeratski, F.; LeBleu, V.; Dowlatshahi, D.; Sugimoto, H.; Arian, K.; Fan, Y.; Huang, L.; Wills, D.; Lilla, S.; Hodge, K.; Zanivan, S.; McAndrews, K.; Kalluri, R.
10.1101/2023.11.02.565371 — cancer biology — Posted on 2023-11-04
4247 Automated single-cell omics end-to-end framework with data-driven batch inference
Wang, Y.; Thistlethwaite, W.; Tadych, A.; Ruf-Zamojski, F.; Bernard, D. J.; Cappuccio, A.; Zaslavsky, E.; Chen, X.; Sealfon, S. C.; Troyanskaya, O. G.
10.1101/2023.11.01.564815 — bioinformatics — Posted on 2023-11-04
4249 Influence of Reinforcement and Its Omission on Trial-by-Trial Changes of Response Bias in Perceptual Decision-Making
Stuettgen, M. C.; Dietl, A.; Stoilova Eckert, V. V.; de la Cuesta Ferrer, L.; Blanke, J.-H.; Koss, C.; Jaekel, F.
10.1101/2023.11.02.565253 — animal behavior and cognition — Posted on 2023-11-04
4253 Epigenetic predictors of species maximum lifespan and other life history traits in mammals
Li, C. Z.; Haghani, A.; Yan, Q.; Lu, A. T.; Zhang, J.; Fei, Z.; Ernst, J.; Yang, X.; Gladyshev, V. N.; Raj, K.; Seluanov, A.; Gorbunova, V.; Horvath, S.
10.1101/2023.11.02.565286 — evolutionary biology — Posted on 2023-11-04
4255 Survivability and Life Support in Sealed Mini-Ecosystems with Simulated Planetary Soils
Sato, T.; Abe, K.; Koseki, J.; Seto, M.; Yokoyama, J.; Akashi, T.; Terada, M.; Kadowaki, K.; Yoshida, S.; Yamashiki, Y. A.; Shimamura, T.
10.1101/2023.11.02.565408 — ecology — Posted on 2023-11-04
4257 Murine uterine gland branching is necessary for gland function in implantation
Granger, K.; Fitch, S.; Shen, M.; Lloyd, J.; Bhurke, A.; Hancock, J.; Ye, X.; Arora, R.
10.1101/2023.11.01.565233 — developmental biology — Posted on 2023-11-04
4261 HDAC inhibitors rescue MeCP2T158M speckles in a high content screen
Debyser, Z.; Christ, F.; Lata, R.; Nijs, M.; Klaassen, H.; Versele, M.; Kellens, R.; Steegmans, L.
10.1101/2023.11.02.565272 — cell biology — Posted on 2023-11-04
4263 FABP7 Progenitors are a Targetable Metabolic Root in the BRCA1 Breast
McCloskey, C. W.; Zhang, B.; Waas, M.; Abazari, G.; Vyas, F.; Aliar, K.; Tharmapalan, P.; Kuttanamkuzhi, A.; Narala, S.; Cruikshank, J.; Hofer, S. O. P.; Jackson, H. W.; Kislinger, T.; Berman, H. K.; Khokha, R.
10.1101/2023.11.02.565360 — cell biology — Posted on 2023-11-04
4269 Human neural stem cells restore spatial memory in a transgenic Alzheimer's disease mouse model by an immunomodulating mechanism
Chen, K. S.; Noureldein, M. H.; McGinley, L. M.; Hayes, J. M.; Rigan, D. M.; Kwentus, J. F.; Mason, S. N.; Mendelson, F. E.; Savelieff, M. G.; Feldman, E. L.
10.1101/2023.11.01.565161 — neuroscience — Posted on 2023-11-04
4270 Indistinguishable network dynamics can emerge from unalike plasticity rules
Ramesh, P.; Confavreux, B.; Goncalves, P. J.; Vogels, T. P.; Macke, J. H.
10.1101/2023.11.01.565168 — neuroscience — Posted on 2023-11-04
4273 Back to the holobiont: ecophysiological and systemic responses of rooted-cuttings inoculated with a synthetic community
Sandrini, M.; Chitarra, W.; Pagliarani, C.; Moffa, L.; Petrozziello, M.; Colla, P.; Balestrini, R.; Nerva, L.
10.1101/2023.11.02.565299 — plant biology — Posted on 2023-11-04
4274 Phylogenetic diversity and regionalization in the temperate arid zone
Folk, R. A.; Maassoumi, A.; Siniscalchi, C.; Kates, H. R.; Soltis, D. E.; Soltis, P. S.; Belitz, M. W.; Guralnick, R. P.
10.1101/2023.11.01.565216 — plant biology — Posted on 2023-11-04
4275 Dehydrozaluzanin C- derivative protects septic mice by alleviating over-activated inflammatory response and promotes the phagocytosis of macrophages
Zou, y.; Xiang, t.; Xu, l.; Zhang, h.; Ma, y.; Zhang, l.; Zhou, c.; Wu, x.; Huang, q.; Lei, b.; Mu, j.; Qin, X.; Jiang, X.; Zheng, y.
10.1101/2023.11.01.565192 — pathology — Posted on 2023-11-04
4276 Dissection and reconstruction of the colorectal cancer tumor microenvironment
Broguiere, N.; Lorenzo-Martin, L. F.; Ragusa, S.; Rivest, F.; Brandenberg, N.; Hohnel, S.; Dutta, D.; Gueye, M.; Alpern, D.; Deplancke, B.; Kandalaft, L.; Coukos, G.; Homicsko, K.; Lutolf, M. P.
10.1101/2023.11.01.565169 — cancer biology — Posted on 2023-11-04
4277 Somatic structural variants driving distinct modes of oncogenesis in melanoma
Conway, J. M.; Gillani, R.; Crowdis, J.; Reardon, B.; Park, J.; Han, S.; Titchen, B.; Benamar, M.; Haq, R.; Van Allen, E.
10.1101/2023.11.01.565187 — cancer biology — Posted on 2023-11-04
4282 The role of the AP-1 adaptor complex in outgoing and incoming membrane traffic
Robinson, M. S.; Antrobus, R.; Sanger, A.; Davies, A. K.; Gershlick, D. C.
10.1101/2023.11.02.565271 — cell biology — Posted on 2023-11-04
4283 Design rules for efficient endosomal escape
Zoltek, M.; Vazquez-Maldonado, A. L.; Zhang, X.; Dadina, N.; Lesiak, L.; Schepartz, A.
10.1101/2023.11.03.565388 — cell biology — Posted on 2023-11-04
4285 Loss of CTRP10 results in female obesity with preserved metabolic health
Chen, F.; Sarver, D. C.; Saqib, M.; Velez, L. M.; Aja, S.; Seldin, M. M.; Wong, G. W.
10.1101/2023.11.01.565163 — physiology — Posted on 2023-11-04
4286 Dynamic Regulation of Innate Lymphoid Cell Development During Ontogeny
Wu, T.; Chen, S.; Ma, J.; Zhu, X.; Luo, M.; Wang, Y.; Tian, Y.; Sun, Q.; Zhang, J.; Guo, X.; Zhang, X.; Zhu, Y.; Wu, L.
10.1101/2023.11.01.565141 — immunology — Posted on 2023-11-04
4293 A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver triglycerides accumulation
Jin, Y.; Kozan, D.; Anderson, J.; Hensley, M.; Shen, M.-C.; Wen, J.; Moll, T.; Kozan, H.; Rawls, J. F.; Farber, S. A.
10.1101/2023.11.01.565134 — physiology — Posted on 2023-11-04
4294 A general and efficient representation of ancestral recombination graphs
Wong, Y.; Ignatieva, A.; Koskela, J.; Gorjanc, G.; Wohns, A. W.; Kelleher, J.
10.1101/2023.11.03.565466 — genetics — Posted on 2023-11-04
4295 Reprogramming early cortical astroglia into neurons with hallmarks of fast-spiking parvalbumin-positive interneurons by phospho-site deficient Ascl1
Marichal, N.; Peron, S.; Beltran Arranz, A.; Galante, C.; Scarante, F. F.; Wiffen, R.; Schuurmans, C.; Karow, M.; Gascon, S.; Berninger, B.
10.1101/2023.11.03.565289 — neuroscience — Posted on 2023-11-04
4296 Attentional bias toward fearful faces is associated with maternal postnatal distress and alterations in white matter microstructure in 5-year-old females
Kumpulainen, V.; Kataja, E.-L.; Pulli, E. P.; Copeland, A. M.; Silver, E. A.; Haikio, T.; Saukko, E.; Korja, R.; Karlsson, L.; Karlsson, H.; Tuulari, J. J.
10.1101/2023.11.01.565103 — neuroscience — Posted on 2023-11-04
4297 Tonically active GABAergic neurons in the dorsal periaqueductal gray control the initiation and execution of instinctive escape
Stempel, A. V.; Evans, D. A.; Pavon Arocas, O.; Claudi, F.; Lenzi, S. C.; Kutsarova, E.; Margrie, T. W.; Branco, T.
10.1101/2023.11.03.565561 — neuroscience — Posted on 2023-11-04
4298 Ggnbp2 regulates synaptic development and autophagy in motor neurons
Kerwin, S. K.; Carrodus, N.; Kewin, A.; Lin, T.; Qian, X.; McRae, A.; Yang, J.; Collins, B. M.; Wray, N.; Garton, F.; Millard, S.
10.1101/2023.11.03.565470 — neuroscience — Posted on 2023-11-04
4302 Genomic fingerprints of the world's soil ecosystems
Graham, E. B.; Garayburu-Caruso, V. A.; Wu, R.; Zheng, J.; Jones, G.
10.1101/2023.11.02.563126 — ecology — Posted on 2023-11-03
4306 Ligand-Dependent Mechanisms of C-C Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics
Gu, S.; Maurya, S.; Lona, A.; Borrega-Roman, L.; Salanga, C.; Gonzalez, D. J.; Kufareva, I.; Handel, T.
10.1101/2023.11.01.565224 — cell biology — Posted on 2023-11-03
4307 Alteration in Gut Microbiome and Intestinal Barrier Function caused by Efavirenz versus Dolutegravir Treatments in Mice
Tang, Q.; Pan, H.-e.; Liu, Z.; Deng, Z.; Zhong, Q.-Y.; Cao, H.-h.; Ye, J.-y.; Li, J.; Li, X.-y.; Zhu, H.-p.; Chen, S.
10.1101/2023.11.01.565232 — immunology — Posted on 2023-11-03
4308 Transcranial ultrasound stimulation effect in the redundant and synergistic networks consistent across macaques
Gatica, M.; Atkinson-Clement, C.; Mediano, P. A. M.; Alkhawashki, M.; Ross, J.; Sallet, J.; Kaiser, M.
10.1101/2023.11.02.564776 — neuroscience — Posted on 2023-11-03
4310 Collective Information and Communication in Morphologically Distinct Astrocytes
Mennona, N. J.; Barile, B.; Kang, H.; Benfenati, V.; Nicchia, G. P.; O'Neill, K. M.; Losert, W.
10.1101/2023.11.01.565176 — biophysics — Posted on 2023-11-03
4313 Pervasive relaxed selection in termite genomes
Ewart, K. M.; Ho, S. Y. M.; Chowdhury, A.-A.; Jaya, F. R.; Kinjo, Y.; Bennett, J.; Bourguignon, T.; Rose, H.; Lo, N.
10.1101/2023.11.01.565207 — evolutionary biology — Posted on 2023-11-03
4317 Ciliary intrinsic mechanisms regulate dynamic ciliary extracellular vesicle release from sensory neurons
Wang, J.; Saul, J.; Nikonorova, I. A.; Cruz, C. N.; Power, K. M.; Nguyen, K. C.; Hall, D. H.; Barr, M. M.
10.1101/2023.11.01.565151 — cell biology — Posted on 2023-11-03
4318 Decellularized Banana Leaves: Eco-Friendly Scaffolds for Cell-Based Seafood
Sarkarat, R.; Banavar, A.; Amirvaresi, A.; Li, X.; Nguyen, C.; Kaplan, D. L.; Nitin, N.; Ovissipour, R.
10.1101/2023.11.03.565310 — synthetic biology — Posted on 2023-11-03
4320 Plasma proteome signature of canine acute haemorrhagic diarrhoea syndrome (AHDS)
Huber, L.; Kuropka, B.; Doulidis, P. G.; Baszler, E.; Martin, L.; Rosu, A.; Kulmer, L.; Frizzo Ramos, C.; Rodriguez Rojas, A.; Burgener, I. A.
10.1101/2023.11.03.565505 — biochemistry — Posted on 2023-11-03
4321 Using Vibrio natriegens for high-yield production of challenging expression targets and for protein deuteration
Mojica, N.; Kersten, F.; Montserrat-Canals, M.; Huhn, G. R.; Tislevoll, A. M.; Cordara, G.; Teter, K.; Krengel, U.
10.1101/2023.11.03.565449 — biochemistry — Posted on 2023-11-03
4323 Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycerol)phosphate lipids by Pla2g15
Jain, R.; Geoghegan, G.; Davidson, J.; Nesbitt, D. J.; Abe, A.; Chao, X.; James, I.; Cavanagh, A. T.; Michorowska, S.; Verma, R.; Schueler, K. L.; Hinkoka-Galcheva, V.; Shishkova, E.; Ding, W.-X.; Coon, J. J.; Shayman, J.; Simcox, J.
10.1101/2023.11.03.565498 — biochemistry — Posted on 2023-11-03
4327 Structural basis for plasmid restriction by SMC JET nuclease
Roisne-Hamelin, F.; Liu, H. W.; Taschner, M.; Li, Y.; Gruber, S.
10.1101/2023.11.03.565488 — molecular biology — Posted on 2023-11-03
4328 Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors
He, Q.; Yuan, Q.; Shan, H.; Wu, C.; Gu, Y.; Wu, K.; Hu, W.; Zhang, Y.; Xu, H. E.; Zhao, L.
10.1101/2023.11.03.565472 — molecular biology — Posted on 2023-11-03
4329 A novel stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids
Podgorski, J. M.; Podgorski, J.; Abad, L.; Jacobs-Sera, D.; Freeman, K. G.; Brown, C.; Hatfull, G.; Luque, A.; White, S. J.
10.1101/2023.11.03.565530 — molecular biology — Posted on 2023-11-03
4330 A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity
Alexander, M.; Upadhyay, V.; Rock, R.; Ramirez, L.; Puchalska, P.; Orellana, D.; Ang, Q. Y.; Turnbaugh, J. A.; Tian, Y.; Dumlao, D.; Nayak, R. R.; Patterson, A. D.; Newman, J. C.; Crawford, P. A.; Turnbaugh, P. J.
10.1101/2023.11.02.565382 — microbiology — Posted on 2023-11-03
4331 The evolution of multiply substituted isotopologues of methane during microbial aerobic oxidation
Li, J.; Chiu, B. K.; Piasecki, A. M.; Feng, X.; Landis, J. D.; Marcum, S.; Young, E. D.; Leavitt, W. D.
10.1101/2023.11.02.565373 — microbiology — Posted on 2023-11-03
4333 Cas13-based amplification-free quantification of aberrant RNAs during influenza virus infection
Lamb, C.; Pitre, E.; Elshina, E.; Rigby, C.; Bisht, K.; Jalal, H.; Myhrvold, C.; te Velthuis, A. J. W.
10.1101/2023.11.03.565460 — microbiology — Posted on 2023-11-03
4335 Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4+ T cells
Sambaturu, N.; Fray, E. J.; Wu, F.; Zitzmann, C.; Simonetti, F. R.; Barouch, D. H.; Siliciano, J. D.; Siliciano, R. F.; Ribeiro, R. M.; Perelson, A. S.; Molina-Paris, C.; Leitner, T.
10.1101/2023.11.03.565539 — microbiology — Posted on 2023-11-03
4336 Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors
Wang, F.; Holmes, M. J.; Hong, H. J.; Thaprawat, P.; Kannan, G.; Huynh, M.-H.; Schultz, T. L.; Licon, M. H.; Lourido, S.; Sullivan, W. J.; O Leary, S. E.; Carruthers, V. B.
10.1101/2023.11.03.565545 — microbiology — Posted on 2023-11-03
4338 Virological characteristics of the SARS-CoV-2 BA.2.86 variant
Tamura, T.; Mizuma, K.; Nasser, H.; Deguchi, S.; Padilla-Blanco, M.; Uriu, K.; Tolentino, J. E. M.; Tsujino, S.; Suzuki, R.; Kojima, I.; Nao, N.; Shimizu, R.; Jonathan, M.; Kosugi, Y.; Guo, Z.; Hinay, A. A.; Putri, O.; Kim, Y.; Tanaka, Y. L.; Asakura, H.; Nagashima, M.; Sadamasu, K.; Yoshimura, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Saito, A.; Ito, J.; Irie, T.; Zahradnik, J.; Ikeda, T.; Takayama, K.; Matsuno, K.; Fukuhara, T.; Sato, K.
10.1101/2023.11.02.565304 — microbiology — Posted on 2023-11-03
4342 Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
Delhaye, L.; Moschonas, G. D.; Fijalkowska, D.; Verhee, A.; De Sutter, D.; Van de Steene, T.; De Meyer, M.; Van Moortel, L.; De Bosscher, K.; Eyckerman, S.
10.1101/2023.11.03.565112 — biochemistry — Posted on 2023-11-03
4344 Shear stress and very low levels of ligand synergize toactivate ALK1 signaling in endothelial cells
Cheng, Y.-W.; Anzell, A. R.; Schwartze, T. A.; Hinck, C. S.; Hinck, A. P.; Roman, B. L.; Davidson, L.
10.1101/2023.11.01.565194 — cell biology — Posted on 2023-11-03
4345 Membrane potential mediates an ancient mechano-transduction mechanism for multi-cellular homeostasis
Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Neliat, A. R.; Schuttler, J.; Benites, N. C.; Liu, X.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.
10.1101/2023.11.02.565386 — cell biology — Posted on 2023-11-03
4352 Pseudouridine guides germline small RNA transport and epigenetic inheritance
Herridge, R. P.; Dolata, J.; Migliori, V.; de Santis Alves, C.; Borges, F.; Van Ex, F.; Parent, J.-S.; Lin, A.; Bajczyk, M.; Leonardi, T.; Hendrick, A.; Schorn, A. J.; Kouzarides, T.; Martienssen, R. A.
10.1101/2023.05.27.542553 — genetics — Posted on 2023-11-03
4360 Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
Webster, A. N.; Becker, J. J.; Li, C.; Schwalbe, D. C.; Kerspern, D.; Karolczak, E. O.; Godschall, E. N.; Belmont-Rausch, D. M.; Pers, T. H.; Lutas, A.; Habib, N.; Guler, A. D.; Krashes, M. J.; Campbell, J. N.
10.1101/2023.10.31.564990 — neuroscience — Posted on 2023-11-03
4363 Developmental pyrethroid exposure disrupts folate metabolism in mouse brain
Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.
10.1101/2023.10.13.562226 — neuroscience — Posted on 2023-11-03
4364 Insomnia subtypes have differentiating deviations in brain structural connectivity
Bresser, T.; Blanken, T. F.; de Lange, S.; Leerssen, J.; Foster-Dingley, J. C.; Lakbila-Kamal, O.; Wassing, R.; Ramautar, J. R.; Stoffers, D.; van den Heuvel, M. P.; Van Someren, E. J. W.
10.1101/2023.11.01.565094 — neuroscience — Posted on 2023-11-03
4365 Mitochondrial CISD1 is a downstream target that mediates PINK1 and Parkin loss-of-function phenotypes
Bitar, S.; Baumann, T.; Weber, C.; Abusaada, M.; Rojas-Charry, L.; Ziegler, P.; Schettgen, T.; Randerath, I. E.; Venkataramani, V.; Michalke, B.; Arena, G.; Krueger, R.; Zhang, L.; Methner, A.
10.1101/2023.09.28.559909 — neuroscience — Posted on 2023-11-03
4368 The soil-borne white root rot pathogen Rosellinia necatrix expresses antimicrobial proteins during host colonization
Chavarro, E.; Snelders, N.; Torres, D.; Kraege, A.; Lopez-Moral, A.; Petti, G.; Punt, W.; Wieneke, J.; Garcia-Velasco, R.; Lopez-Herrera, C.; Seidl, M. F.; Thomma, B.
10.1101/2023.04.10.536216 — plant biology — Posted on 2023-11-03
4369 MicroRNA-541-3p alters lipoproteins to reduce atherosclerosis by degrading Znf101 and Casz1 transcription factors
Ansari, A.; Yadav, P. K.; Zhou, L.; Prakash, B.; Gangula, B.; Ijaz, L.; Christiano, A.; Ahmad, S.; Rimbert, A.; Hussain, M. M.
10.1101/2023.11.01.565110 — physiology — Posted on 2023-11-03
4378 Gene surgery as a potential treatment option for Nephropathic Cystinosis in vitro
Sendino Garvi, E.; Faria, J.; Pou Casellas, C.; Thijssen, S.; Wubbolts, E. J.; Jamalpoor, A.; Harrison, P.; Masereeuw, R.; Janssen, M. J.
10.1101/2023.11.01.565117 — bioengineering — Posted on 2023-11-03
4379 Phylogenomic insights into the first multicellular streptophyte
Bierenbroodspot, M. J.; Darienko, T.; de Vries, S.; Fuerst-Jansen, J. M. R.; Buschmann, H.; Proeschold, T.; Irisarri, I.; de Vries, J.
10.1101/2023.11.01.564981 — evolutionary biology — Posted on 2023-11-03
4381 Safety Assessment of Intravenous Injection of Rat Embryonic Proteome Extract for in-vivo Regenerative Therapies
DARSI, S. R. P.; Kandula, S. k.; barani, K. K.; Pasupulati, A. K.; chikatla, s. s.; Darsi, S. K.; Kamireddy, A. R.; Barra, R. R.; Devarasetty, A. K.; Surampudi, S.
10.1101/2023.10.30.563384 — developmental biology — Posted on 2023-11-03
4383 A biomechanical switch promotes lysosomal remodelling and exocytosis in keloid fibroblasts
Ross, R.; Guo, Y.; Walker, R. N.; Bergamaschi, D.; Shaw, T. J.; Connelly, J. T.
10.1101/2023.11.01.564877 — cell biology — Posted on 2023-11-03
4384 Changes in the Type 2 diabetes gut mycobiome associate with metformin treatment across populations
Van Syoc, E.; Nixon, M. P.; Silverman, J. D.; Luo, Y.; Gonzalez, F. J.; Elbere, I.; Klovins, J.; Patterson, A. D.; Rogers, C. J.; Ganda, E.
10.1101/2023.05.25.542255 — microbiology — Posted on 2023-11-03
4385 Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
Le Quy, K.; Chernigovskaya, M.; Stensland, M.; Singh, S.; Leem, J.; Revale, S.; Galson, J. D.; Nyman, T. A.; Snapkow, I.; Greiff, V.
10.1101/2023.11.01.565093 — immunology — Posted on 2023-11-03
4386 Mediterranean Diet Protects Against a Neuroinflammatory Transcriptome in Temporal Cortex: Associations with Brain Volumetrics, Peripheral Inflammation, Social Isolation, and Anxiety in Nonhuman Primates
Negrey, J.; Frye, B. M.; Johnson, C. S. C.; Snyder-Mackler, N.; Chiou, K.; Lockhart, S. N.; Barcus, R. A.; Whitlow, C. T.; Sutphen, C. L.; Montine, T.; Craft, S.; Shively, C. A.; Register, T. C.
10.1101/2023.11.01.565068 — neuroscience — Posted on 2023-11-03
4388 Transcranial cortex-wide imaging of murine ischemic perfusion with large-field multifocal illumination fluorescence microscopy
Chen, Z.; Zhou, Q.; Droux, J.; Liu, Y.-H.; Glueck, C.; Gezginer, I.; Wyss, M.; Yoshihara, H. A.; Kindler, D. R.; Weber, B.; Wegener, S.; El Amki, M.; Razansky, D.
10.1101/2023.11.01.564959 — neuroscience — Posted on 2023-11-03
4392 A Ralstonia solanacearum type III effector alters the actin and microtubule cytoskeleton to promote bacterial virulence in plants
Hiles, R.; Rogers, A.; Jaiswal, N.; Zhang, W.; Butchacas, J.; Merfa, M.; Klass, T.; Kaser, E.; Jacobs, J. M.; Staiger, C. J.; Helm, M. J.; Iyer-Pascuzzi, A. S.
10.1101/2023.11.01.565113 — plant biology — Posted on 2023-11-03
4393 Sida cordifolia, a medicinal plant is efficacious in models of Huntingtons disease, by reducing ER stress
Simha, P. K.; Mukherjee, C.; Gupta, V. K. G. K.; Sapariya, N. M.; Nagar, P.; Nazeer, A.; Godbole, A.; Sahu, B. S.; Upadhyay, S.
10.1101/2023.11.01.565080 — pharmacology and toxicology — Posted on 2023-11-03
4394 Systems profiling reveals recurrently dysregulated cytokine signaling responses in ER+ breast cancer patients' blood
Orcutt-Jahns, B.; Lima Junior, J. R.; Rockne, R. C.; Matache, A.; Branciamore, S.; Hung, E.; Rodin, A. S.; Lee, P. P.; Meyer, A. S.
10.1101/2023.10.31.564987 — cancer biology — Posted on 2023-11-03
4396 Autophagy regulates tumor growth and metastasis
Qiang, L.; Zhao, B.; Ming, M.; Wang, N.; He, T.-C.; Hwang, S.; Thorburn, A.; He, Y.-Y.
10.1101/2023.10.31.564991 — cancer biology — Posted on 2023-11-03
4402 MIC13 and SLP2 seed the assembly of MIC60-subcomplex to facilitate crista junction formation
Naha, R.; Strohm, R.; Urbach, J.; Wittig, I.; Reichert, A. S.; Kondadi, A. K.; Anand, R.
10.1101/2023.09.04.556207 — biochemistry — Posted on 2023-11-03
4403 The complete human diploid reference genome of RPE-1 identifies the phased epigenetic landscapes from multi-omics data
Volpe, E.; Corda, L.; Di Tommaso, E.; Pelliccia, F.; Ottalevi, R.; Licastro, D.; Formenti, G.; Capulli, M.; Guarracino, A.; Tassone, E.; Giunta, S.
10.1101/2023.11.01.565049 — genomics — Posted on 2023-11-03
4405 Activity in the reticulospinal tract scales with handgrip force in humans
Danielson, T. L.; Gould, L.; DeFreitas, J. M.; MacLennan, R. J.; Ekstrand, C.; Borowsky, R.; Farthing, J. P.; Andrushko, J. W.
10.1101/2023.10.27.563544 — neuroscience — Posted on 2023-11-03
4407 SNAP25 disease mutations change the energy landscape for synaptic exocytosis due to aberrant SNARE interactions
Kadkova, A.; Murach, J.; Pedersen, M.; Malsam, A.; Malsam, J.; Lolicato, F.; Nickel, W.; Soellner, T. H.; Sorensen, J. B.
10.1101/2023.05.21.541607 — neuroscience — Posted on 2023-11-03
4409 The G2 phase controls binary division of Toxoplasma gondii
Hawkins, L. M.; Wang, C.; Chaput, D.; Batra, M.; Marsilia, C.; Awshah, D.; Suvorova, E.
10.1101/2023.07.31.551351 — cell biology — Posted on 2023-11-03
4411 Intrinsically disordered regions in the transcription factor MYC:MAX modulate DNA binding via intramolecular interactions
Schuetz, S.; Bergsdorf, C.; Haenni-Holzinger, S.; Lingel, A.; Renatus, M.; Gossert, A. D.; Jahnke, W.
10.1101/2023.06.21.545551 — biophysics — Posted on 2023-11-03
4412 Hyperactive PI3Kinase delta enables long distance regeneration of the rat corticospinal tract
Karova, K.; Polcanova, Z.; Suchankova, S.; Knight, L.; Nieuwenhuis, B.; Holota, R.; Herynek, V.; Urdzikova, L. M.; Turecek, R.; Kwok, J. C. F.; Verhaagen, J.; Eva, R.; Fawcett, J. W.; Jendelova, P.
10.1101/2023.10.27.564182 — neuroscience — Posted on 2023-11-03
4415 Mechanical imbalance between normal and cancer cells drives epithelial defense against cancer
Gupta, P.; Kayal, S.; Pothapragada, S. P.; Senapati, H. K.; Devendran, P.; Bi, D.; Das, T.
10.1101/2023.09.27.559723 — biophysics — Posted on 2023-11-03
4419 Respiratory modulations of cortical excitabilityand interictal spike timing in focal epilepsy - a case report
Kluger, D. S.; Erdbruegger, T.; Stier, C.; Hoeltershinken, M. B.; Abbasi, O.; Saltafossi, M.; Unnwongse, K.; Wehner, T.; Wellmer, J.; Gross, J.; Wolters, C. H.
10.1101/2023.08.28.555061 — neuroscience — Posted on 2023-11-03
4423 The molecular architecture of the kidney slit diaphragm
Birtasu, A. N.; Wieland, K.; Ermel, U. H.; Rahm, J. V.; Scheffer, M. P.; Flottmann, B.; Heilemann, M.; Grahammer, F.; Frangakis, A. S.
10.1101/2023.10.27.564405 — cell biology — Posted on 2023-11-03
4424 Dopamine and neuromodulation shorten the latency from motor intention to execution in Parkinson's disease
Köhler, R. M.; Binns, T. S.; Merk, T.; Zhu, G.; Yin, Z.; Zhao, B.; Chikermane, M.; Vanhoecke, J.; Busch, J. L.; Habets, J. G. V.; Faust, K.; Schneider, G.-H.; Haufe, S.; Zhang, J.; Kühn, A. A.; Haynes, J.-D.; Neumann, W.-J.
10.1101/2023.10.30.564700 — neuroscience — Posted on 2023-11-03
4425 ATG8 delipidation is dispensable for plant autophagy
Holla, S.; Zou, Y.; Sabljic, I.; Ohlsson, J. A.; Leong, J. X.; Ballhaus, F.; Krebs, M.; Schumacher, K.; Uestuen, S.; Dagdas, Y.; Bozhkov, P.; Minina, E. A.
10.1101/2023.08.23.554513 — plant biology — Posted on 2023-11-03
4426 The dynamic hypoosmotic response of Vibrio cholerae relies on the mechanosensitive channel MscS
Ramsey, K.; Britt, M.; Maramba, J.; Ushijima, B.; Moller, E.; Anishkin, A.; Hase, C.; Sukharev, S.
10.1101/2023.05.08.539864 — biophysics — Posted on 2023-11-03
4427 Transepithelial Electrical Impedance Increase Following Porous Substrate Electroporation Enables Label-Free Delivery
Brooks, J. R.; Heiman, T. C.; Lorenzen, S. R.; Mungloo, I.; Mirfendereski, S.; Park, J. S.; Yang, R.
10.1101/2023.10.17.562630 — bioengineering — Posted on 2023-11-03
4430 Immunosuppressive tumor microenvironment of osteosarcoma
Taylor, A. M.; Ng, P. K. S.; Harder, J. M.; Kumar, P.; Dzis, A. M.; Jillette, N. L.; Goodspeed, A.; Bodlak, A.; Wu, Q.; Isakoff, M. S.; George, J.; Grassman, J. D. S.; Luo, D.; Flynn, W. F.; Courtois, E. T.; Robson, P.; Hayashi, M.; Paulillo, A. T.; de Toledo, S. R. C.; Balarezo, F. S.; Lindsay, A. D.; Hoang, B.; Lau, C. C.
10.1101/2023.11.01.565008 — cancer biology — Posted on 2023-11-03
4435 Transfer of mitochondrial DNA into the nuclear genome during gene editing
Wu, J.; Liu, Y.; Ou, L.; Gan, T.; Zhangding, Z.; Yuan, S.; Liu, M.; Liu, X.; Li, J.; Yin, J.; Xin, C.; Tian, Y.; Hu, J.
10.1101/2023.07.19.549443 — genomics — Posted on 2023-11-03
4437 Chromosome-level genome assemblies of two hemichordates provide new insights into deuterostome origin and chromosome evolution
Lin, C.-Y.; Marletaz, F.; Perez-Posada, A.; Martinez Garcia, P. M.; Schloissnig, S.; Peluso, P.; Conception, G. T.; Bump, P.; Chen, Y.-C.; Chou, C.; Lin, C.-Y.; Fan, T.-P.; Tsai, C.-T.; Gomez Skarmeta, J. L.; Tena, J. J.; Lowe, C. J.; Rank, D. R.; Rokhsar, D. S.; Yu, J.-K.; Su, Y.-H.
10.1101/2023.11.01.564642 — evolutionary biology — Posted on 2023-11-02
4440 A universal mechanism of biomass density homeostasis via ribosomal counterions
Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.
10.1101/2023.08.31.555748 — microbiology — Posted on 2023-11-03
4441 Reinstatement of RIG-I in chickens via genetic modification reveals new insights into the dynamic evolution of avian immune sensors
Sid, H.; von Heyl, T.; Schleibinger, S.; Klinger, R.; Guabiraba, R.; Guillory, V.; Schade, B.; Elleder, D.; Sives, S.; Vervelde, L.; Trapp, S.; Schusser, B.
10.1101/2023.11.01.564710 — immunology — Posted on 2023-11-02
4442 The how, when, and what of odor valence communication between the olfactory bulb and piriform cortex
Norden, F.; Iravani, B.; Schaefer, M.; Winter, A. L.; Lundqvist, M.; Arshamian, A.; Lundström, J. N.
10.1101/2023.11.02.564696 — neuroscience — Posted on 2023-11-02
4443 A simple and reliable method for claustrum localization across age in mice
Shaker, T.; Dagpa, G. J.; Cattoud, V.; Marriott, B. A.; Sultan, M.; Almokdad, M.; Jackson, J.
10.1101/2023.10.31.564789 — neuroscience — Posted on 2023-11-02
4444 Small molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: Development of screening assays and insight into GluK3 structure
Bay, Y.; Venskutonyte, R.; Frantsen, S. M.; Thorsen, T. S.; Musgaard, M.; Frydenvang, K.; Francotte, P.; Pirotte, B.; Biggin, P. C.; Kristensen, A. S.; Boesen, T.; Pickering, D. S.; Gajhede, M.; Kastrup, J. S.
10.1101/2023.11.02.565282 — neuroscience — Posted on 2023-11-02
4448 Transcriptional Control of Neocortical Size and Microcephaly
Barao, S.; Xu, Y.; Vistein, R.; Goff, L.; Nielsen, K.; Bae, B.-I.; Smith, R. S.; Walsh, C. A.; Stein O Brien, G.; Muller, U.
10.1101/2023.11.02.565322 — neuroscience — Posted on 2023-11-02
4449 MolecularWebXR: Multiuser discussions about chemistry and biology in immersive and inclusive VR
Cortes Rodriguez, F. J.; Frattini, G.; Teixeira Pinto Meireles, F.; Terrien, D. A.; Cruz-Leon, S.; Dal Peraro, M.; Schier, E.; Moreno, D. M.; Abriata, L. A.
10.1101/2023.11.01.564623 — scientific communication and education — Posted on 2023-11-02
4451 LMO3 is a suppressor of the basal-like/squamous PDAC subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism
Ohara, Y.; Craig, A. J.; Liu, H.; Yang, S.; Moreno, P.; Dorsey, T. H.; Cawley, H.; Azizian, A.; Gaedcke, J.; Ghadimi, M.; Hanna, N.; Ambs, S.; Hussain, S. P.
10.1101/2023.11.01.564448 — cancer biology — Posted on 2023-11-02
4456 Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
Tomlinson, P. R.; Knox, R.; Perisic, O.; Su, H.; Brierley, G. V.; Williams, R. L.; Semple, R. K.
10.1101/2023.11.02.565250 — biochemistry — Posted on 2023-11-02
4458 Human lncRNAs harbor conserved modules embedded in different sequence contexts
Ballesio, F.; Pepe, G.; Ausiello, G.; Novelletto, A.; Helmer-Citterich, M.; Gherardini, P. F.
10.1101/2023.11.01.565086 — evolutionary biology — Posted on 2023-11-02
4461 Stereo-anomaly is found more frequently in tasks that require discrimination between depths
Baldwin, A. S.; Min, S. H.; Alarcon Carrillo, S.; Wang, Z.; Cheng, Z.; Zhou, J.; Hess, R. F.
10.1101/2023.11.02.564189 — neuroscience — Posted on 2023-11-02
4462 Pathological claustrum activity drives aberrant cognitive network processing in human chronic pain
Stewart, B. W.; Keaser, M. L.; Lee, H.; Margerison, S. M.; Cormie, M. A.; Moayedi, M.; Lindquist, M.; Chen, S.; Mathur, B. N.; Seminowicz, D. A.
10.1101/2023.11.01.564054 — neuroscience — Posted on 2023-11-02
4463 Small-molecule binding and sensing with a designed protein family
Lee, G. R.; Pellock, S. J.; Norn, C.; Tischer, D.; Dauparas, J.; Anishchenko, I.; Mercer, J. A. M.; Kang, A.; Bera, A.; Nguyen, H.; Goreshnik, I.; Vafeados, D.; Roullier, N.; Han, H. L.; Coventry, B.; Haddox, H. K.; Liu, D. R.; Yeh, A. H.-W.; Baker, D.
10.1101/2023.11.01.565201 — biochemistry — Posted on 2023-11-02
4464 The genome and transcriptome of the snail Biomphalaria sudanica s.l.: Immune gene diversification and highly polymorphic genomic regions in an important African vector of Schistosoma mansoni
Pennance, T.; Calvelo, J.; Tennessen, J. A.; Burd, R.; Cayton, J.; Bollmann, S. R.; Blouin, M. S.; Spaan, J. M.; Hoffmann, F. G.; Ogara, G.; Rawago, F.; Andiego, K.; Mulonga, B.; Odhiambo, M.; Loker, E. S.; Laidemitt, M. R.; Lu, L.; Iriarte, A.; Odiere, M.; Steinauer, M. L.
10.1101/2023.11.01.565203 — genomics — Posted on 2023-11-02
4465 Computing Linkage Disequilibrium Aware Genome Embeddings using Autoencoders
Tas, G.; Balvert, M.; Schoenhuth, A.; Veldink, J. H.; Postma, E.; Westerdijk, T.; Project MinE ALS GWAS Consortium,
10.1101/2023.11.01.565013 — genomics — Posted on 2023-11-02
4466 Rab27 in tick extracellular vesicle biogenesis and infection
Butler, L. R.; Singh, N.; Marnin, L.; Valencia, L.; O'Neal, A.; Cabrera Paz, F.; Shaw, D. K.; Oliva Chavez, A.; Pedra, J.
10.1101/2023.11.02.565357 — microbiology — Posted on 2023-11-02
4468 What is Slough?A pilot study to define the proteomic and microbial composition of wound slough and its implications for wound healing.
Townsend, E.; Cheong, J. A.; Razieta, M.; Fritz, B. G.; Bjarnsholt, T.; Malone, M.; Ousey, K.; Swanson, T.; Schultz, G.; Gibson, A.; Kalan, L.
10.1101/2023.11.02.565225 — microbiology — Posted on 2023-11-02
4469 qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes
Philip, R.; Sharma, A.; Matellan, L.; Erpf, A. C.; Hsu, W.-H.; Tkach, J. M.; Wyatt, H. D. M.; Pelletier, L.
10.1101/2023.11.01.565029 — molecular biology — Posted on 2023-11-02
4474 Apobec-Mediated Retroviral Hypermutation In Vivo is Dependent on Mouse Strain
Byun, H.; Singh, G. B.; Xu, W. K.; Das, P.; Reyes, A.; Battenhouse, A.; Wylie, D. C.; Lozano, M. M.; Dudley, J. P.
10.1101/2023.11.02.565355 — microbiology — Posted on 2023-11-02
4475 COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS.
Castillo-Aliaga, C.; Blanchard, A. M.; Castro-Seriche, S.; Hidalgo-Hermoso, E.; Jerez-Morales, A.; Loose, M. W.; Tarlinton, R. E.
10.1101/2023.11.02.563952 — microbiology — Posted on 2023-11-02
4478 Recruitment of FBXO22 for Targeted Degradation of NSD2
Nie, D. Y.; Tabor, J. R.; Li, J.; Kutera, M.; St-Germain, J.; Hanley, R. P.; WOLF, E. Z.; Paulakonis, E.; Kenney, T. M. G.; Duan, S.; Shrestha, S.; Owens, D. D.; Pon, A.; Szewczyk, M.; Lamberto, A. J.; Menes, M.; Li, F.; Barsyte-Lovejoy, D.; Brown, N. G.; Barsotti, A. M.; Stamford, A. W.; Collins, J. L.; Wilson, D. J.; Raught, B.; Licht, J.; James, L.; Arrowsmith, C.
10.1101/2023.11.01.564830 — biochemistry — Posted on 2023-11-02
4479 Myeloperoxidase-dependent tyrosine halogenation potentiates alpha-defensins functions
Foti, A.; Hurwitz, R.; Textoris-Taube, K.; Muelleder, M.; Biswas, A.; Fahjen, P.; Winkler, M.; Abu Abed, U.; Humme, D.; Thee, S.; Prasse, A.; Seeliger, B.; Ralser, M.; Zychlinsky, A.
10.1101/2023.11.01.565105 — biochemistry — Posted on 2023-11-02
4480 De novo design of allosterically switchable protein assemblies
Pillai, A.; Idris, A.; Philomin, A.; Weidle, C.; Skotheim, R.; Leung, P. J. Y.; Broerman, A.; Demakis, C.; Borst, A. J.; Praetorius, F.; Baker, D.
10.1101/2023.11.01.565167 — biochemistry — Posted on 2023-11-02
4481 The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new rule?
Sreenivasan, S.; Heffren, P.; Suh, K.-S.; Rodnin, M. V.; Kosa, E.; Fenton, A. W.; Ladokhin, A.; Smith, P. E.; Fontes, J. D.; Swint-Kruse, L.
10.1101/2023.11.02.565367 — biochemistry — Posted on 2023-11-02
4482 Design of efficient artificial enzymes using crystallographically-enhanced conformational sampling
Rakotoharisoa, R. V.; Seifinoferest, B.; Zarifi, N.; Miller, J. D. M.; Rodriguez, J. M.; Thompson, M. C.; Chica, R. A.
10.1101/2023.11.01.564846 — biochemistry — Posted on 2023-11-02
4485 Cultivation, chemistry, and genome of Psilocybe zapotecorum
Miller, D. R.; Jacobs, J. T.; Rockefeller, A.; Singer, H.; Bollinger, I. M.; Conway, J.; Slot, J. R.; Cliffel, D. E.
10.1101/2023.11.01.564784 — molecular biology — Posted on 2023-11-02
4487 Structural determinants of pure antiestrogenicity
Marine, D.; Shaikh, F.; El Ezzy, M.; Thiombane, K.; Weber, S.; Poupart, J.; Mendoza-Sanchez, R.; Gao, Z.; Gleason, J.; Schuetz, D. A.; Greene, G.; Marinier, A.; Fanning, S. W.; MADER, S.
10.1101/2023.10.31.564979 — molecular biology — Posted on 2023-11-02
4489 LARP1 senses free ribosomes to coordinate supply and demand of ribosomal proteins
Saba, J. A.; Huang, Z.; Schole, K. L.; Ye, X.; Bhatt, S. D.; Li, Y.; Timp, W.; Cheng, J.; Green, R.
10.1101/2023.11.01.565189 — molecular biology — Posted on 2023-11-02
4490 Diffusion of DNA on Atomically Flat 2D Material Surfaces
Shin, D. H.; Kim, S. H.; Coshic, K.; Watanabe, K.; Taniguchi, T.; Verbiest, G.; Caneva, S.; Aksimentiev, A.; Steeneken, P. G.; Joo, C.
10.1101/2023.11.01.565159 — molecular biology — Posted on 2023-11-02
4491 Structural basis of saccharine derivative inhibition of carbonic anhydrase IX
Leitans, J.; Kazaks, A.; Bogans, J.; Supuran, C. T.; Akopjana, I.; Ivanova, J.; Zalubovskis, R.; Tars, K.
10.1101/2023.11.01.565239 — molecular biology — Posted on 2023-11-02
4495 Characterizing constitutive promoters across the Proteobacteria
Schuster, L.; Mejia, C.; Trujillo Rodriguez, L.; Kairalla, E.; Reisch, C. R.; Chevrette, M. G.; Dias, R.
10.1101/2023.11.02.564426 — synthetic biology — Posted on 2023-11-02
4496 IDO-1 inhibition improves outcome after fluid percussion injury in adult male rats
Sadek, M.; Stover, K. R.; Liu, X.; Reed, M. A.; Weaver, D. F.; Reid, A. Y.
10.1101/2023.10.31.564953 — neuroscience — Posted on 2023-11-02
4497 Essential oil terpenes may inhibit steroidogenic cytochrome P450 activities.
Sharma, K.; Lanzilotto, A.; Yakubu, J.; Therkelsen, S.; Vöegel, C. D.; du Toit, T.; Jorgensen, F. S.; Pandey, A. V.
10.1101/2023.10.31.564977 — pharmacology and toxicology — Posted on 2023-11-02
4498 Lymphatic Dysfunction Models an Autoimmune Emphysema Phenotype of Chronic Obstructive Pulmonary Disease
Summers, B.; Kim, K.; Lu, T. M.; Houghton, S.; Quintero, J. R.; Cala-Garcia, J.; Pannellini, T.; Polverino, F.; Lis, R.; Trivedi, A.; Reed, H. O.
10.1101/2023.10.31.564938 — pathology — Posted on 2023-11-02
4499 The cellular landscape of the endochondral bone during the transition to extrauterine life
Rueda, A. D.; Salvador-Martinez, I.; Sospedra-Arrufat, I.; Alcaina-Caro, A.; Fernandez-Minan, A.; Burgos-Ruiz, A. M.; Cases, I.; Mohedano, A.; Tena, J. J.; Heyn, H.; Lopez-Rios, J.; Nusspaumer, G.
10.1101/2023.07.18.549529 — cell biology — Posted on 2023-11-02
4501 The human mitochondrial mRNA structurome reveals mechanisms of gene expression
Moran, J. C.; Brivanlou, A.; Brischigliaro, M.; Fontanesi, F.; Rouskin, S.; Barrientos, A.
10.1101/2023.10.31.564750 — molecular biology — Posted on 2023-11-02
4502 Excitatory effects of dentate gyrus mossy cells on granule cells and area CA3: an vitro and in vivo study in adult mice.
Bernstein, H. L.; Lu, Y.-L.; Leary, P.; Jain, S.; LaFrancois, J. J.; Lacefield, C. O.; Botterill, J. J.; Scharfman, H. E.
10.1101/2020.06.06.137844 — neuroscience — Posted on 2023-11-02
4503 Denoising Diffusion MRI: Considerations and implications for analysis
Patron, J. P. M.; Moeller, S.; Andersson, J. L. R.; Ugurbil, K.; Yacoub, E.; Sotiropoulos, S. N.
10.1101/2023.07.24.550348 — neuroscience — Posted on 2023-11-02
4507 Colocalization of Cancer Associated Biomarkers on Single Extracellular Vesicles for Early Cancer Detection
Salem, D. P.; Bortolin, L. T.; Gusenleitner, D.; Grosha, J.; Zabroski, I. O.; Biette, K. M.; Banerjee, S.; Sedlak, C. R.; Byrne, D. M.; Hamzeh, B. F.; King, M. S.; Cuoco, L. T.; Santos-Heiman, T.; Duff, P. A.; Winn-Deen, E. S.; Guettouche, T.; Mattoon, D. R.; Huang, E. K.; Schekman, R.; Couvillon, A. D.; Sedlak, J. C.
10.1101/2023.02.07.527360 — cancer biology — Posted on 2023-11-02
4509 Acylation of MLKL impacts its function in necroptosis
Pradhan, A. J.; Chitkara, S.; Ramirez, R.; Monje-Galvan, V.; Sancak, Y.; Atilla-Gokcumen, G. E.
10.1101/2023.08.19.553906 — biochemistry — Posted on 2023-11-02
4513 The mechanistic basis of evolutionary transitions between grey, slate, and blue colour in Tanagers (Thraupidae)
Babarovic, F.; Cooney, C. R.; Zinn, T.; Drobniak, S. M.; Janas, K.; Kennedy, J. D.; Nadeau, N. J.; Parnell, A. J.; Thomas, G. H.; Burg, S.
10.1101/2023.10.31.564904 — evolutionary biology — Posted on 2023-11-02
4516 Discovery of a multipotent cell type from the term human placenta
Vadakke-Madathil, S.; Wang, B.; Oniskey, M.; Dekio, F.; Brody, R.; Gelber, S.; Sperling, R.; Chaudhry, H. W.
10.1101/2023.08.02.551028 — cell biology — Posted on 2023-11-02
4517 Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression
Zhuang, X.; Gallo, G.; Sharma, P.; Ha, J.; Magri, A.; Borrmann, H.; Harris, J. M.; Tsukuda, S.; Bentley, E.; Kirby, A.; Neck, S. d.; Yang, H.; Balfe, P.; Wing, P. A.; Matthews, D. A.; Harris, A. L.; Kipar, A.; Stewart, J. P.; Bailey, D.; McKeating, J. A.
10.1101/2023.10.31.564923 — molecular biology — Posted on 2023-11-02
4518 Driver lines for studying associative learning in Drosophila
Shuai, Y.; Sammons, M.; Sterne, G. R.; Hibbard, K.; Yang, H.; Yang, C.-P.; Managan, C.; Siwanowicz, I.; Lee, T.; Rubin, G. M.; Turner, G. C.; Aso, Y.
10.1101/2023.09.15.557808 — neuroscience — Posted on 2023-11-02
4519 A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
Bayati, A.; Ayoubi, R.; Aguila, A.; Zorca, C. E.; Han, C.; Banks, E.; Nguyen-Renou, E.; Luo, W.; shlaifer, I.; Del Cid-Pellitero, E.; Yaqubi, M.; Fon, E. A.; Stratton, J. A.; Durcan, T. M.; Nahirney, P. C.; McPherson, P. S.
10.1101/2023.05.29.542776 — neuroscience — Posted on 2023-11-02
4521 Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization
Szakacs, H. M.; Mutlu, M. C.; Balestrieri, G.; Gombos, F.; Braun, J.; Kringelbach, M. L.; Deco, G.; Kovacs, I.
10.1101/2023.08.30.555584 — neuroscience — Posted on 2023-11-02
4522 Dominant energetics in multi-component bio-molecular condensates
Qian, D.; Ausserwoger, H.; Sneideris, T.; Farag, M.; Pappu, R. V.; Knowles, T.
10.1101/2023.06.12.544666 — biophysics — Posted on 2023-11-02
4523 DystoGen Compendium: A comprehensive resource of ACMG annotated movement disorder associated genetic variants
Saikia, B. J.; Gaharwar, U.; Poojary, M.; Mhaske, A.; Paul, S.; Kumar, M.; Pandhare, K.; Sharma, S.; Rophina, M.; Rastogi, S.; Karal, M.; Scaria, V.; BK, B.
10.1101/2023.10.31.564874 — bioinformatics — Posted on 2023-11-02
4525 Towards Biohybrid Lung Development? Inflammatory Conditions Disrupt Endothelial Layer Integrity on Gas Exchange Membranes
Cheremkhina, M.; Babendreyer, A.; Neullens, C. T.; Krapp, S.; Pabst, A.; Ohl, K.; Tenbrock, K.; Ruetten, S.; Ludwig, A.; Cornelissen, C. G.; Thiebes, A. L.; Jockenhoevel, S.
10.1101/2023.10.31.564901 — bioengineering — Posted on 2023-11-02
4528 Covalent Degrader of the Oncogenic Transcription Factor β-Catenin
Gowans, F. A.; Forte, N.; Hatcher, J.; Huang, O. W.; Wang, Y.; Poblano, B. E. A.; Wertz, I. E.; Nomura, D. K.
10.1101/2023.10.31.565018 — biochemistry — Posted on 2023-11-02
4529 Functional characterization of the disease-associated CCL2 rs1024611G-rs13900T haplotype: The role of the RNA-binding protein HuR
Akhtar, F.; Ruiz, J. H.; Liu, Y.-G.; Resendez, R. G.; Feliers, D.; Morales, L. D.; Diaz-Badillo, A.; Lehman, D. M.; Arya, R.; Alvarenga, J. C. L.; Blangero, J.; Duggirala, R.; Mummidi, S.
10.1101/2023.10.31.564937 — genomics — Posted on 2023-11-02
4530 Oligo-barcodes illuminate holocentric karyotype evolution in Rhynchospora (Cyperaceae)
Mata-Sucre, Y.; Parteka, L. M.; Ritz, C.; Gatica-Arias, A.; Felix, L. P.; Thomas, W. W.; Souza, G.; Vanzela, A. L. L.; Pedrosa-Harand, A.; Marques, A.
10.1101/2023.10.31.564898 — genomics — Posted on 2023-11-02
4534 Mosquito thermal tolerance is remarkably constrained across a large climatic range
Couper, L. I.; Farner, J. E.; Lyberger, K. P.; Lee, A. S.; Mordecai, E. A.
10.1101/2023.03.02.530886 — ecology — Posted on 2023-11-02
4539 NEUTROPHILS ARE INDISPENSABLE FOR ADVERSE CARDIAC REMODELING IN HEART FAILURE
Antipenko, S. V.; Mayfield, N.; Jinno, M.; Gunzer, M.; Ismahil, M. A.; Hamid, T.; Prabhu, S. S.; Rokosh, G.
10.1101/2023.10.31.565035 — immunology — Posted on 2023-11-02
4540 Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C HIV-1 Vaccine in Rhesus Macaques
Verma, A.; Hawes, C. E.; Elizaldi, S. R.; Smith, J. C.; Rajasundaram, D.; Pedersen, G. K.; Shen, X.; Williams, L. D.; Tomaras, G. D.; Kozlowski, P. A.; Amara, R. R.; Iyer, S. S.
10.1101/2023.07.18.549515 — immunology — Posted on 2023-11-02
4541 Aberrant splicing in Huntington's disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification.
Nguyen, T. B.; Miramontes, R.; Chillon-Marinas, C.; Maimon, R.; Vazquez-Sanchez, S.; Lau, A. L.; McClure, N. R.; England, W. E.; Singha, M.; Stocksdale, J. T.; Jang, K.-H.; Jung, S.; McKnight, J. I.; Ho, L. N.; Faull, R. L. M.; Steffan, J. S.; Reidling, J. C.; Jang, C.; Lee, G.; Cleveland, D. W.; Lagier-Tourenne, C.; Spitale, R. C.; Thompson, L. M.
10.1101/2023.10.31.565004 — neuroscience — Posted on 2023-11-02
4542 Hippocampal contributions to novel spatial learning are both age-related and age-invariant
Zheng, L.; Gao, Z.; Doner, S.; Oyao, A.; Forloines, M.; Grilli, M. D.; Barnes, C. A.; Ekstrom, A. D.
10.1101/2023.06.28.546918 — neuroscience — Posted on 2023-11-02
4545 A visual paired associate learning (vPAL) paradigm to study memory consolidation during sleep
Schmidig, F. J.; Geva-Sagiv, M.; Falach, R.; Yakim, S.; Gat, Y.; Sharon, O.; Fried, I.; Nir, Y.
10.1101/2023.03.28.534494 — neuroscience — Posted on 2023-11-02
4546 Cell type-specific representation of spatial context in the rat prefrontal cortex
Brunner, H.; Kim, H.; Ahrlund-Richter, S.; Lunteren, J. v.; Crestani, A. P.; Meletis, K.; Carlen, M.
10.1101/2023.10.31.564949 — neuroscience — Posted on 2023-11-02
4547 Synanthropic Culicidae (Diptera) in three fragments of Atlantic Forest in northern Parana, Brazil.
Grossi, L. E.; da Silva, L. B.; Novaes, V. M.; Golias, H. C.; da Silva, M. A. N.; ZEQUI, J. A. C.
10.1101/2023.10.31.565019 — zoology — Posted on 2023-11-02
4548 Replication poison treated BRCA1-deficient breast cancers are prone to MRE11 over-resection resulting in single strand DNA accumulation and mitotic catastrophe
Tabet, I.; Orhan, E.; Candiello, E.; Fenou, L.; Velazquez, C.; Orsetti, B.; Rodier, G.; Jacot, W.; Ribeyre, C.; Sardet, C.; Theillet, C.
10.1101/2023.10.31.564929 — cancer biology — Posted on 2023-11-02
4549 Genomic hypomethylation in cell-free DNA predicts responses to checkpoint blockade in lung and breast cancer
Kim, K.; Kim, H.; Shin, I.; Noh, S.-J.; Kim, J. Y.; Suh, K. J.; Kim, Y.-N.; Lee, J.-Y.; Cho, D.-Y.; Kim, S. H.; Kim, J. H.; Lee, S.-H.; Choi, J. K.
10.1101/2023.10.31.565052 — cancer biology — Posted on 2023-11-02
4551 Engineering microvascular networks using a KLF2 reporter to probe flow-dependent endothelial cell function
Blazeski, A.; Floryan, M. A.; Fajardo-Ramirez, O. R.; Meibalan, E.; Ortiz-Urbina, J.; Angelidakis, E.; Shelton, S. E.; Kamm, R. D.; Garcia-Cardena, G.
10.1101/2023.10.31.565021 — bioengineering — Posted on 2023-11-02
4552 Integrated single-nuclei and spatial transcriptomic analysis reveals propagation of early acute vein harvest and distension injury signaling pathways following arterial implantation
Michaud, M. E.; Mota, L.; Bakhtiari, M.; Thomas, B. E.; Tomeo, J.; Pilcher, W.; Contreras, M.; Ferran, C.; Bhasin, S.; Pradhan-Nabzdyk, L.; LoGerfo, F. W.; Liang, P.; Bhasin, M.
10.1101/2023.10.31.564995 — genomics — Posted on 2023-11-02
4556 Natural genetic variation quantitatively regulates heart-rate and -dimension
Gierten, J.; Welz, B.; Fitzgerald, T. W.; Thumberger, T.; Hummel, O.; Leger, A.; Weber, P.; Hassel, D.; Hubner, N.; Birney, E.; Wittbrodt, J.
10.1101/2023.09.01.555906 — genetics — Posted on 2023-11-02
4558 Genome evolution and introgression in the New Zealand mud snails Potamopyrgus estuarinus and Potamopyrgus kaitunuparaoa
Fields, P.; Jalinsky, J.; Bankers, L.; McElroy, K.; Sharbrough, J.; Higgins, C.; Morgan-Richards, M.; Boore, J.; Neiman, M.; Logsdon, J. M.
10.1101/2023.10.31.565016 — evolutionary biology — Posted on 2023-11-02
4562 Three-dimensional visualization of blood vessels in human gliomas based on tissue clearing and deep learning
Wang, X.; Yang, X.; He, D.; Luo, Y.; Huang, Q.; Li, T.; Ye, Z.; Ye, C.; Zhang, M.; Lai, H.; Xu, Y.; Sun, H.
10.1101/2023.10.31.564955 — neuroscience — Posted on 2023-11-02
4563 Brain-derived neurotrophic factor contributes to activity-induced muscle pain in male but not female mice
Hayashi, K.; Lesnak, J. B.; Plumb, A. N.; Janowski, A. J.; Smith, A. F.; Hill, J. K.; Sluka, K. A.
10.1101/2023.10.31.565022 — neuroscience — Posted on 2023-11-02
4567 Auditory cues modulate the short timescale dynamics of STN activity during stepping in Parkinson's disease
Yeh, C.-H.; Xu, Y.; Shi, W.; FitzGerald, J. J.; Green, A. L.; Fischer, P.; Tan, H.; Oswal, A.
10.1101/2023.10.31.565053 — neuroscience — Posted on 2023-11-02
4574 Encoding of the colorectal cancer metabolic program through MICU2
Robert, A.; Crottes, D.; Bourgeais, J.; Gueguen, N.; Chevrollier, A.; Dumas, J.-F.; Servais, S.; Domingo, I.; Chadet, S.; Sobilo, J.; Herault, O.; Lecomte, T.; Vandier, C.; Raoul, W.; Gueguinou, M.
10.1101/2023.10.31.564893 — cancer biology — Posted on 2023-11-02
4576 Targeted Deletion of All Known Thyroid Hormone Receptors Causes Maturation Retardation and Early-onset Degeneration of Cochlear Outer Sulcus
Ma, X.; Jiang, F.; Han, S.; Zhang, Y.; Sun, L.; Qu, J.; Yin, H.; Chen, Y.; Tang, J.; He, D. Z. Z.; Zhang, W. J.; Xie, Z.
10.1101/2023.10.31.565054 — developmental biology — Posted on 2023-11-02
4577 An immunohistochemical atlas of necroptotic pathway expression
Chiou, S.; Al-Ani, A.; Pan, Y.; Patel, K.; Kong, I.; Whitehead, L.; Light, A.; Young, S.; Barrios, M.; Sargeant, C.; Rajasekhar, P.; Zhu, L.; Hempel, A.; Lin, A.; Rickard, J.; Hall, C.; Gangatirkar, P.; Yip, R.; Cawthorne, W.; Jacobsen, A.; Horne, C.; Ioannidis, L.; Hansen, D.; Day, J.; Wicks, I.; Law, C. W.; Ritchie, M. E.; Bowden, R.; Hildebrand, J.; O'Reilly, L.; Silke, J.; Giulino-Roth, L.; Tsui, E.; Rogers, K.; Hawkins, E.; Christensen, B.; Murphy, J. M.; Samson, A. L.
10.1101/2023.10.31.565039 — cell biology — Posted on 2023-11-02
4578 NK and NKT cells in the pathogenesis of Hidradenitis suppurativa: Novel therapeutic strategy through targeting of CD2
Kashyap, M. P.; Mishra, B.; Sinha, R.; Jin, L.; Kumar, N.; Goliwas, K. F.; Deshane, J.; Elewski, B. E.; Elmets, C. A.; Athar, M.; Mukhtar, M. S.; Raman, C.
10.1101/2023.10.31.565057 — immunology — Posted on 2023-11-02
4579 N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer's disease
Joerg, M.; Plehn, J.; Kristen, M.; Lander, M.; Walz, L.; Lietz, C.; Wijns, J.; Pichot, F.; Rojas-Charry, L.; Wirtz Martin, K.; Ruffini, N.; Kreim, N.; Gerber, S.; Motorin, Y.; Endres, K.; Rossmanith, W.; Methner, A.; Helm, M.; Friedland, K.
10.1101/2023.10.31.564907 — neuroscience — Posted on 2023-11-02
4584 Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages
Iglesia, M. D.; Jayasinghe, R. G.; Chen, S.; Terekhanova, N. V.; Herndon, J. M.; Storrs, E.; Karpova, A.; Zhou, D. C.; Naser Al Deen, N.; Shinkle, A. T.; Lu, R. J.-H.; Caravan, W.; Houston, A.; Zhao, Y.; Sato, K.; Lal, P.; Street, C.; Rodrigues, F. M.; Southard-Smith, A. N.; Targino da Costa, A. L. N.; Zhu, H.; Mo, C.-K.; Crowson, L.; Fulton, R. S.; Wyczalkowski, M. A.; Fronick, C. C.; Fulton, L. A.; Sun, H.; Davies, S. R.; Appelbaum, E. L.; Chasnoff, S. E.; Carmody, M.; Brooks, C.; Liu, R.; Wendl, M. C.; Oh, C.; Bender, D.; Cruchaga, C.; Harari, O.; Bredemeyer, A.; Lavine, K.; Bose, R.; Marge
10.1101/2023.10.31.565031 — cancer biology — Posted on 2023-11-02
4593 Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury
Eisdorfer, J. T.; Thackray, J.; Theis, T.; Vivinetto, A.; Ricci, M. T.; Lin, S.; Oputa, O.; Martinez, A. M.; Nacht, H. D.; Tschang, M.; Mahmood, M.; Tucker, A.; Pusuloori, S.; Zmoyro, L.; Abraira Lab Computational Group, ; Popovich, P.; Ferguson, A. R.; McTigue, D.; Tysseling, V. M.; Dulin, J.; Hollis, E.; Datta, S. R.; Abraira, V. E. G.
10.1101/2023.10.31.564826 — neuroscience — Posted on 2023-11-02
4597 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging
Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.
10.1101/2023.10.30.564754 — bioengineering — Posted on 2023-11-02
4602 Sensory Feedback and Central Neuronal Interactions in Mouse Locomotion
Molkov, Y.; Yu, G.; Ausborn, J.; Bouvier, J.; Danner, S. M.; Rybak, I. A.
10.1101/2023.10.31.564886 — systems biology — Posted on 2023-11-02
4603 Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues
Sanghvi, N.; Calvo-Alcaniz, C.; Rajagopal, P.; Scalera, S.; Canu, V.; Sinha, S.; Schischlik, F.; Wang, K.; Madan, S.; Shulman, E.; Papanicolau-Sengos, A.; Blandino, G.; Ruppin, E.; Nair, N.
10.1101/2023.10.30.564810 — cancer biology — Posted on 2023-11-02
4604 Looking for a needle in a haystack: de novo phenotypic target identification reveals Hippo pathway-mediated miR-202 regulation of egg production
Janati-Idrissi, S.; Roza de Abreu, M.; Guyomar, C.; de Mello, F.; Nguyen, T.; Mechkouri, N.; Gay, S.; Montfort, J.; Gonzalez, A. A.; Abbasi, M.; Bugeon, J.; Thermes, V.; Seitz, H.; Bobe, J.
10.1101/2023.10.31.560894 — genomics — Posted on 2023-11-02
4606 A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies
Li, X.; Chen, H.; Selvaraj, M. S.; Van Buren, E.; Zhou, H.; Wang, Y.; Sun, R.; McCaw, Z. R.; Yu, Z.; Arnett, D. K.; Bis, J. C.; Blangero, J.; Boerwinkle, E.; Bowden, D. W.; Brody, J. A.; Cade, B. E.; Carson, A. P.; Carlson, J. C.; Chami, N.; Chen, Y.-D. I.; Curran, J. E.; de Vries, P. S.; Fornage, M.; Franceschini, N.; Freedman, B. I.; Gu, C.; Heard-Costa, N. L.; He, J.; Hou, L.; Hung, Y.-J.; Irvin, M. R.; Kaplan, R. C.; Kardia, S. L. R.; Kelly, T.; Konigsberg, I.; Kooperberg, C.; Kral, B. G.; Li, C.; Loos, R. J. F.; Mahaney, M. C.; Martin, L. W.; Mathias, R. A.; Minster, R. L.; Mitchell, B. D
10.1101/2023.10.30.564764 — genetics — Posted on 2023-11-02
4608 Shifted levels of sleep and activity under darkness as mechanisms underlying ectoparasite resistance
Benoit, J. B.; Ajayi, O. M.; Webster, A.; Grieshop, K.; Lewis, D.; Talbott, H.; Bose, J.; Polak, M.
10.1101/2023.10.30.564749 — evolutionary biology — Posted on 2023-11-02
4610 Conspicuous shell shape plasticity across lake-stream habitats in a freshwater mussel (Pyganodon grandis)
Keogh, S. M.; Minerich, B. J.; Ohlman, L. M.; Pletta, M. E.; Scheunemann, A. E.; Schroeder, Z. K.; Secrist, Z. A.; Franzen, A. J.; Sietman, B. E.; Simons, A. M.
10.1101/2023.10.30.564758 — ecology — Posted on 2023-11-02
4611 Loss of Nkd1 is dominant over loss of Axin2 in regulating Wnt signaling
Bell, I.; Khan, H.; Stutt, N.; Horn, M.; Hydzik, T.; Lum, W.; Rea, V.; Clapham, E.; Hoeg, L.; Van Raay, T. J.
10.1101/2023.10.30.563773 — developmental biology — Posted on 2023-11-02
4613 Multi-spectral Fluorescent Reporter Influenza A Viruses Allow for in vivo Studies of Innate Immune Function in Zebrafish
Soos, B.-L.; Ballinger, A.; Weinstein, M.; Foreman, H.; Grampone, J.; Weafer, S.; Aylesworth, C.; King, B.
10.1101/2023.10.31.564888 — immunology — Posted on 2023-11-02
4615 Multi-region calcium imaging in freely behaving mice with ultra-compact head-mounted fluorescence microscopes
Xue, F.; Li, F.; Zhang, K.-m.; Ding, L.; Wang, Y.; Zhao, X.; Xu, F.; Zhang, D.; Sun, M.; Lau, P.-M.; Zhu, Q.; Zhou, P.; Bi, G.-Q.
10.1101/2023.10.30.564709 — neuroscience — Posted on 2023-11-02
4617 Gamma sensory stimulation and effects on the brain
Kahn, M.; Chan, D.; Wang, D.; Geigenmuller, U.; Blanco-Duque, C.; Murdock, M.; Suk, H.-J.; Jackson, B. L.; Jakkamsetti, V.; Niederst, E.; Brown, E.; Boyden, E. S.; McHugh, T.; Adaikkan, C.; Singer, A.; Hanslmayr, S.; Tsai, L.-H.
10.1101/2023.10.30.564197 — neuroscience — Posted on 2023-11-02
4621 Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis Throughout the Day
Malik, D. M.; Rhoades, S. D.; Zhang, S. L.; Sengupta, A.; Barber, A.; Haynes, P.; Arnadottir, E. S.; Pack, A.; Kibbey, R. G.; Sehgal, A.; Weljie, A. M.
10.1101/2023.10.30.564837 — systems biology — Posted on 2023-11-02
4622 Affinity purification-mass spectrometry and single fiber physiology/proteomics reveals mechanistic insights of C18ORF25
Ng, Y.-K.; Blazev, R.; McNamara, J.; Dutt, M.; Molendijk, J.; Porrello, E. R.; Elliott, D.; Parker, B. L.
10.1101/2023.10.30.564812 — physiology — Posted on 2023-11-02
4623 Berberine impairs spermatogenesis in mice by modulating ornithine metabolism via gut microbiota regulation
Qu, W.; Xu, Y.; Lei, J.; Yang, J.; Shi, H.; Wang, J.; Yu, X.; Chen, J.; Wang, B.; Han, Y.; Luo, M.; Liu, R.
10.1101/2023.10.30.564855 — pharmacology and toxicology — Posted on 2023-11-02
4624 Characterization of alternative splicing in high-risk Wilms tumors
Trink, Y.; Urbach, A.; Dekel, B.; Hohenstein, P.; Goldberger, J.; Kalisky, T.
10.1101/2023.10.30.564809 — cancer biology — Posted on 2023-11-02
4625 Ultrahigh Resolution Lipid Mass Spectrometry Imaging of High-Grade Serous Ovarian Cancer Mouse Models
Ma, X.; Botros, A.; Yun, S. R.; Park, E. Y.; Kim, O.; Park, S.; Pham, T.-H.; Chen, R.; Palaniappan, M.; Matzuk, M. M.; Kim, J.; Fernandez, F. M.
10.1101/2023.10.30.564760 — cancer biology — Posted on 2023-11-02
4626 FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma
Gillis, K.; Orellana, W. A.; Wilson, E.; Parnell, T. J.; Fort, G.; Dadzie, H. E.; Zhang, X.; Snyder, E.
10.1101/2023.10.30.564775 — cancer biology — Posted on 2023-11-02
4627 POU5F1B is a human-restricted ROCK inhibitor-sensitive oncoprotein that restructures membrane nanodomains to increase cell adhesion
Simo Riudalbas, L.; Offner, S.; Abrami, L.; Unterauer, E. M.; Duc, J.; Planet, E.; Jungmann, R.; van der Goot, G.; Trono, D.
10.1101/2023.10.30.564723 — cancer biology — Posted on 2023-11-02
4630 A foundation model for bioactivity prediction using pairwise meta-learning
Feng, B.; Liu, Z.; Huang, N.; Xiao, Z.; Zhang, H.; Mirzoyan, S.; Xu, H.; Hao, J.; Xu, Y.; Zhang, M.; Wang, S.
10.1101/2023.10.30.564861 — bioinformatics — Posted on 2023-11-02
4638 Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of ZDBF2
Kobayashi, H.; Igaki, T.; Kumamoto, S.; Tanaka, K.; Takashima, T.; Suzuki, S.; Hayashi, M.; Renfree, M. B.; Kawahara, M.; Saito, S.; Kobayashi, T.; Nagashima, H.; Nakano, K.; Matsunari, H.; Uchikura, A.; Kiyonari, H.; Kaneko, M.; Imai, H.; Nakabayashi, K.; Lorincz, M. C.; Kurimoto, K.
10.1101/2023.10.30.564869 — genomics — Posted on 2023-11-02
4644 Critical role of CD206+ macrophages in organizing anti-tumor immunity
Ray, A.; Hu, K. H.; Kersten, K.; Kuhn, N. F.; Samad, B.; Combes, A. J.; Krummel, M. F.
10.1101/2023.10.31.560822 — immunology — Posted on 2023-11-02
4645 FASlpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus
Bohat, R.; Liang, X.; Chen, Y.; Xu, C.; Zheng, N.; Guerrero, A.; Jaffery, R.; Egan, N. A.; Robles, A.; Hicks, M. J.; Du, Y.; Chen, X.; Mohan, C.; Peng, W.
10.1101/2023.11.01.563607 — immunology — Posted on 2023-11-02
4646 Mining the neuroimaging literature
Dockes, J.; Oudyk, K. M.; De La Vega, A. M.; Poline, J.-B.
10.1101/2023.10.30.564783 — neuroscience — Posted on 2023-11-02
4648 Hierarchical encoding of reward and effort across the cortex and basal ganglia during cost-benefit decision making
Härmson, O.; Grennan, I.; Perry, B.; Toth, R.; McNamara, C.; Manohar, S. G.; Cagnan, H.; Walton, M. E.; Sharott, A.
10.1101/2023.10.31.563750 — neuroscience — Posted on 2023-11-02
4651 Deep Phenotyping of Sleep in Drosophila
Keles, M. F.; Sapcı, A. O. B.; Brody, C.; Palmer, I.; Le, C.; Tastan, O.; Keles, S.; Wu, M.
10.1101/2023.10.30.564733 — neuroscience — Posted on 2023-11-02
4652 Developmental differences in canonical cortical networks: insights from microstructure-informed tractography
Genc, S.; Schiavi, S.; Chamberland, M.; Tax, C. M. W.; Raven, E. P.; Daducci, A.; Jones, D. K.
10.1101/2023.10.30.564863 — neuroscience — Posted on 2023-11-02
4655 Enabling population protein dynamics through Bayesian modeling
Lehmann, S.; Vialaret, J.; Gabelle, A.; Bauchet, L.; Villemin, J.-P.; Hirtz, C.; Colinge, J.
10.1101/2023.10.30.564713 — systems biology — Posted on 2023-11-02
4656 Small but significant genetic differentiation among populations of Phyllachora maydis in the midwestern United States revealed by microsatellite (SSR) markers.
Ross, T. J.; Jumbam, B.; Bonkowski, J.; Chaky, J.; Chilvers, M.; Goodwin, S. B.; Kleczewski, N. M.; Mueller, D. S.; Robertson, A. E.; Smith, D. L.; Telenko, D. E. P.
10.1101/2023.10.31.563566 — pathology — Posted on 2023-11-02
4658 Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness
Battistini, C.; Kenny, H. A.; Nieddu, V.; Melocchi, V.; Decio, A.; Gatto, A.; Ghioni, M.; Porta, F. M.; Giavazzi, R.; Colombo, N.; Bianchi, F.; Lengyel, E.; Cavallaro, U.
10.1101/2023.10.30.564779 — cancer biology — Posted on 2023-11-02
4659 Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer
Hughson, A. L.; Hannon, G.; Salama, N. A.; Vrooman, T. G.; Stockwell, C. A.; Mills, B. N.; Garrett-Larsen, J.; Qui, H.; Katerji, R.; Benoodt, L.; Johnston, C. J.; Murphy, J. D.; Kruger, E.; Ye, J.; Gavras, N. W.; Keeley, D. C.; Qin, S. S.; Lesch, M. L.; Muhitch, J. B.; Love, T. M. T.; Calvi, L. M.; Lord, E. M.; Luheshi, N.; Elyes, J.; Linehan, D.; Gerber, S. A.
10.1101/2023.10.30.564833 — cancer biology — Posted on 2023-11-02
4663 Decoding Heterogenous Single-cell Perturbation Responses
Song, B.; Liu, D.; Dai, W.; McMyn, N.; Wang, Q.; Yang, D.; Krejci, A.; Vasilyev, A.; Untermoser, N.; Loregger, A.; Song, D.; Williams, B.; Rosen, B.; Cheng, X.; Chao, L.; Kale, H.; Zhang, H.; Diao, Y.; Bürckstümmer, T.; Siliciano, J. M.; Li, J. J.; Siliciano, R.; Huangfu, D.; Li, W.
10.1101/2023.10.30.564796 — bioinformatics — Posted on 2023-11-02
4666 Crossroads of assembling a moss genome: navigating contaminants and horizontal gene transfer in the moss Physcomitrellopsis africana
Vuruputoor, V. S.; Starovoitov, A.; Cai, Y.; Liu, Y.; Rahmatpour, N.; Hedderson, T. A.; Wilding, N.; Wegrzyn, J. L.; Goffinet, B.
10.1101/2023.10.30.564737 — genomics — Posted on 2023-11-02
4675 CZ CELLxGENE Discover: A single-cell data platform for scalable exploration, analysis and modeling of aggregated data
CZI Single-Cell Biology, ; Abdulla, S.; Aevermann, B.; Assis, P.; Badajoz, S.; Bell, S. M.; Bezzi, E.; Cakir, B.; Chaffer, J.; Chambers, S.; Cherry, J. M.; Chi, T.; Chien, J.; Dorman, L.; Gloria, N.; Garcia-Nieto, P.; Hastie, M.; Hegeman, D.; Hilton, J.; Huang, T.; Infeld, A.; Istrate, A.-M.; Jelic, I.; Katsuya, K.; Kim, Y. J.; Liang, K.; Lin, M.; Lombardo, M.; Marshall, B.; Martin, B.; McDade, F.; Megill, C.; Patel, N.; Predeus, A.; Raymor, B.; Robatmili, B.; Rogers, D.; Rutherford, E.; Sadgat, D.; Shin, A.; Small, C.; Smith, T.; Sridharan, P.; Tarashansky, A.; Tavares, N.; Thomas, H.; Tolop
10.1101/2023.10.30.563174 — cell biology — Posted on 2023-11-02
4676 Decreased fucosylation impacts epithelial integrity and increases risk for COPD.
Swaby, C.; Yeung-Luk, B.; Thapa, S.; Nishida, K.; Wally, A.; Ghosh, B.; Niederkofler, A.; Luk, S.; Girgis, M.; Keller, A.; Cortez, C.; Ramaswamy, S.; Wilmsen, K.; Bouche, L.; Dell, A.; Drummond, M. B.; Putcha, N.; Haslam, S. M.; Mathias, R.; Hansel, N. N.; Sheng, J.; Sidhaye, V. K.
10.1101/2023.10.31.564805 — cell biology — Posted on 2023-11-02
4678 WTAP is Transcriptionally Regulated by p65 and Promotes Inflammation through m6A Modification and Phase Separation
Ge, Y.; Chen, R.; Ling, T.; Liu, B.; Huang, J.; Cheng, Y.; Lin, Y.; Chen, H.; Xie, X.; Xia, G.; Luo, G.; Yuan, S.; Xu, A.
10.1101/2023.10.30.564747 — immunology — Posted on 2023-11-02
4679 Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation.
Leishman, S.; Aljadeed, N. M.; Qian, L.; Cockcroft, S.; Behmoaras, J.; Anand, P. K.
10.1101/2023.10.30.564549 — immunology — Posted on 2023-11-02
4680 Dopamine and neuromodulation shorten the latency from motor intention to execution in Parkinson's disease
Koehler, R. M.; Binns, T. S.; Merk, T.; Zhu, G.; Yin, Z.; Zhao, B.; Chikermane, M.; Vanhoecke, J.; Busch, J. L.; Habets, J.; Faust, K.; Schneider, G.-H.; Haufe, S.; Zhang, J.; Kuehn, A. A.; Haynes, J.-D.; Neumann, W.-J.
10.1101/2023.10.30.564700 — neuroscience — Posted on 2023-11-02
4682 Adenosine triggers astrocyte reactivity to drive the pathogenesis of sepsis-associated encephalopathy
Guo, Q.; Gobbo, D.; Zhao, N.; Liu, Q.; Fang, L.-P.; Gampfer, T. M.; Meyer, M. R.; Bai, X.; Bian, S.; Scheller, A.; Kirchhoff, F.; Huang, W.
10.1101/2023.10.30.563169 — neuroscience — Posted on 2023-11-02
4683 Attenuating amyloid-beta pathology in mice with in situ programmed astrocytes
Zhang, L.; Lu, S.; Jia, Y.-b.; Hou, S.-j.; Zhu, J.; Liu, X.-g.; Sun, X.-y.; Huang, Y.-r.; Zhao, Y.-x.; Ren, H.; Liu, C.-y.; Cui, F.; Liu, D.-q.; Du, X.-y.; Niu, X.-y.; li, L.-j.; Wang, K.; Liang, S.-y.; Yang, J.-j.; Ji, S.-y.; Sun, L.; Zhou, W.-w.; Xie, X.-x.; Yu, X.-l.; Wang, X.; Liu, R.-t.
10.1101/2023.10.30.564697 — neuroscience — Posted on 2023-11-02
4686 Skeletal-Muscle Glutamine Synthase is Upregulated in Preclinical Prion Diseases
Caredio, D.; Koderman, M.; Frontzek, K.; Sorce, S.; Nuvolone, M.; Bremer, J.; Schwarz, P.; Sellitto, S.; Streichenberger, N.; Scheckel, C.; Aguzzi, A.
10.1101/2023.10.31.564879 — neuroscience — Posted on 2023-11-02
4687 NREM sleep oscillations and their relations with sleep-dependent memory consolidation in early course psychosis and first-degree relatives
Denis, D.; Baran, B.; Mylonas, D.; Spitzer, C.; Raymond, N.; Talbot, C.; Kohnke, E.; Stickgold, R.; Keshavan, M.; Manoach, D. S.
10.1101/2023.10.30.564703 — neuroscience — Posted on 2023-11-02
4688 BatCRISPRi: Bacillus titratable CRISPRi for dynamic control in Bacillus subtilis
Florez, A. F.; Castillo-Hair, S.; Gutierrez-Lopez, L.; Eaton, D.; Paulsson, J.; Garner, E. C.
10.1101/2023.11.01.565046 — synthetic biology — Posted on 2023-11-02
4690 Development of Corynebacterium glutamicum as a monoterpene production platform
Luckie, B. A.; Kashyap, M.; Pearson, A. N.; Chen, Y.; Liu, Y.; Valencia, L. E.; Romero, A. C.; Hudson, G. A.; Tao, X. B.; Wu, B.; Petzold, C. J.; Keasling, J. D.
10.1101/2023.10.31.565027 — synthetic biology — Posted on 2023-11-02
4691 Beacon-based sleep status and physical activity monitoring in humans.
Kikusui, T.; Yagisawa, M.; Koyama, K.; Fujiwara, K.; Kume, K.; Nomoto, K.; Nagasawa, M.
10.1101/2023.10.30.564338 — physiology — Posted on 2023-11-02
4692 Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response via AP1 dichotomy in pancreatic cancer
Klein, L.; Tu, M.; Krebs, N.; Urbach, L.; Grimm, D. G.; Latif, M. U.; Penz, F.; Chan, N.; Aliar, K.; Vyas, F.; Kishore, U.; Hessmann, E.; Trumpp, A.; Espinet, E.; Papantonis, A.; Khokha, R.; Ellenrieder, V.; Gruenwald, B. T.; Singh, S. K.
10.1101/2023.10.30.563552 — cancer biology — Posted on 2023-11-02
4693 Unearthing SRSF1's Novel Function in Binding and Unfolding of RNA G-Quadruplexes
De Silva, N. I. U.; Lehman, N.; Fargason, T. E.; Paul, T.; Zhang, Z.; Zhang, J.
10.1101/2023.10.30.563137 — biophysics — Posted on 2023-11-02
4697 Structural insights into viral hijacking of p53 by E6 and E6AP
Sandate, C. R.; Chakraborty, D.; Kater, L.; Kempf, G.; Thoma, N. H.
10.1101/2023.11.01.565136 — biophysics — Posted on 2023-11-02
4702 Spatial and single-cell transcriptomics illuminate bat immunity and barrier tissue evolution
Levinger, R.; Tussia-Cohen, D.; Friedman, S.; Lender, Y.; Nissan, Y.; Fraimovitch, E.; Gavriel, Y.; Tearle, J.; Kolodziejczyk, A.; Gomes, T.; Kunowska, N.; Weinberg, M.; Donati, G.; James, K. R.; Yovel, Y.; Hagai, T.
10.1101/2023.10.30.564705 — genomics — Posted on 2023-11-02
4705 The genetic basis of dynamic non-photochemical quenching and photosystem II efficiency in fluctuating light reveals novel molecular targets for maize (Zea mays) improvement
Ferguson, J. N.; Caproni, L.; Walter, J.; Shaw, K.; Thein, M. S.; Mager, S.; Taylor, G.; Cackett, L.; Mathan, J.; Vath, R. L.; Martin, L.; Genty, B.; Pe, M. E.; Lawson, T.; Dell'Acqua, M.; Kromdijk, J.
10.1101/2023.11.01.565118 — plant biology — Posted on 2023-11-02
4706 Stimulation of Neurons and Astrocytes via Temporally Interfering Electric Fields
Ahtiainen, A.; Leydolph, L.; Tanskanen, J. M. A.; Hunold, A.; Haueisen, J.; Hyttinen, J. A. K.
10.1101/2023.10.30.564774 — neuroscience — Posted on 2023-11-02
4707 Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output
Joosten, S. E. P.; Gregoricchio, S.; Stelloo, S.; Yapici, E.; Huang, F.; Donaldson Collier, M.; Morova, T.; Altintas, B.; Kim, Y.; Canisius, S.; Korkmaz, G.; Lack, N.; Vermeulen, M.; Linn, S.; Zwart, W.
10.1101/2023.10.30.564691 — genomics — Posted on 2023-11-02
4709 Terrestrial land cover shapes fish diversity in major subtropical rivers
Zhang, H.; Blackman, R. C.; Furrer, R.; Osathanunkul, M.; Brantschen, J.; Di Muri, C.; Harper, L. R.; Haenfling, B.; Niklaus, P. A.; Pellissier, L.; Schaepman, M. E.; Zong, S.; Altermatt, F.
10.1101/2023.10.30.564688 — ecology — Posted on 2023-11-02
4714 Interactive visualization of whole eukaryote genome alignments using NCBI's Comparative Genome Viewer (CGV)
Rangwala, S. H.; Rudnev, D. V.; Ananiev, V. V.; Asztalos, A.; Benica, B.; Borodin, E. A.; Bouk, N.; Evgeniev, V. I.; Kodali, V. K.; Lotov, V.; Mozes, E.; Oh, D.-H.; Omelchenko, M. V.; Savkina, S.; Sukharnikov, E.; Virothaisakun, J.; Murphy, T. D.; Pruitt, K. D.; Schneider, V. A.
10.1101/2023.10.30.564672 — genomics — Posted on 2023-11-02
4718 Improved detection of methylation in ancient DNA
Sawyer, S.; Gelabert, P.; Yakir, B.; Lizcano, A. L.; Sperduti, A.; Bondioli, L.; Cheronet, O.; Neugebauer-Maresch, C.; Teschler-Nicola, M.; Novak, M.; Pap, I.; Szikossy, I.; Hajdu, T.; Meshorer, E.; Carmel, L.; Pinhasi, R.
10.1101/2023.10.31.564722 — genomics — Posted on 2023-11-02
4719 The shared genetic architecture and evolution of human language and musical rhythm
Alagoez, G.; Eising, E.; Mekki, Y.; Bignardi, G.; Fontanillas, P.; 23andMe Research Team, ; Nivard, M. G.; Luciano, M.; Cox, N. J.; Fisher, S. E.; Gordon, R. L.
10.1101/2023.11.01.564908 — genomics — Posted on 2023-11-02
4720 Physical performance and telomere length in older adults
Martinez-Ezquerro, J. D.; Ortiz-Ramirez, M.; Garcia-delaTorre, P.; Gonzalez-Covarrubias, V.; Sanchez-Garcia, S.
10.1101/2023.10.30.564820 — genetics — Posted on 2023-11-01
4721 A deep catalog of protein-coding variation in 985,830 individuals
Sun, K. Y.; Bai, X.; Chen, S.; Bao, S.; Zhang, C.; Kapoor, M.; Backman, J.; Joseph, T.; Maxwell, E.; Mitra, G.; Gorovits, A.; Mansfield, A.; Boutkov, B.; Gokhale, S.; Habegger, L.; Marcketta, A.; Locke, A.; Kessler, M.; Sharma, D.; Staples, J.; Bovjin, J.; Gelfman, S.; Gioia, A. D.; Rajagopal, V.; Lopez, A.; Varela, J. R.; Alegre-Diaz, J.; Berumen, J.; Tapia-Conyer, R.; Kuri-Morales, P.; Torres, J.; Emberson, J.; Collins, R.; Regeneron Genetics Center, ; RGC-ME Cohort Partners, ; Cantor, M.; Thornton, T.; Kang, H. M.; Overton, J.; Shuldiner, A.; Cremona, M. L.; Nafde, M.; Baras, A.; Abecasis
10.1101/2023.05.09.539329 — genetics — Posted on 2023-11-02
4724 Linking the genetic structure of neuroanatomical phenotypes with psychiatric disorders
Auvergne, A.; Traut, N.; Henches, L.; Troubat, L.; Frouin, A.; Boetto, C.; Kazem, S.; Julienne, H.; Toro, R.; Aschard, h.
10.1101/2023.11.01.564329 — genetics — Posted on 2023-11-02
4727 Cell type-specific representation of spatial context in the rat prefrontal cortex
Brunner, H.; Kim, H.; Ahrlund-Richter, S.; Lunteren, J. v.; Crestani, A. P.; Carlen, M.
10.1101/2023.10.31.564949 — neuroscience — Posted on 2023-11-02
4728 Adolescent social anxiety is associated with diminished discrimination of anticipated threat and safety
Hur, J.; Tillman, R. M.; Kim, H. C.; Didier, P.; Anderson, A. S.; Islam, S.; Stockbridge, M. D.; De Los Reyes, A.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.
10.1101/2023.10.30.564701 — neuroscience — Posted on 2023-11-02
4729 Relating sex differences in cortical and hippocampal microstructure to sex hormones
Kuechenhoff, S.; Bayrak, S.; Zsido, R. G.; Saberi, A.; Bernhardt, B.; Weis, S.; Schaare, H. L.; Sacher, J.; Eickhoff, S.; Valk, S.
10.1101/2023.11.01.565213 — neuroscience — Posted on 2023-11-02
4731 Estimating multimodal brain variability in schizophrenia spectrum disorders: A worldwide ENIGMA study
Omlor, W.; Rabe, F.; Fuchs, S.; Cecere, G.; Homan, S.; Surbeck, W.; Kallen, N.; Georgiadis, F.; Spiller, T.; Seifritz, E.; Weickert, T.; Bruggemann, J.; Weickert, C.; Potkin, S.; Hashimoto, R.; Sim, K.; Rootes-Murdy, K.; Quide, Y.; Houenou, J.; Banaj, N.; Vecchio, D.; Piras, F.; Piras, F.; Spalletta, G.; Salvador, R.; Karuk, A.; Pomarol-Clotet, E.; Rodrigue, A.; Pearlson, G.; Glahn, D.; Tomecek, D.; Spaniel, F.; Skoch, A.; Kirschner, M.; Kaiser, S.; Kochunov, P.; Fan, F.-M.; Andreassen, O.; Westlye, L. T. A.; Berthet, P.; Calhoun, V.; Howells, F. M.; Uhlmann, A.; Scheffler, F.; Stein, D.; Iase
10.1101/2023.09.22.559032 — neuroscience — Posted on 2023-11-02
4733 Multiomics-assisted characterization of rice-Yellow Stem Borer interaction provides genomic and mechanistic insights into stem borer tolerance in rice
CG, G.; Bangale, U.; Balija, V.; Ballichatla, S.; Potupureddi, G.; Rao, D.; Varma, P.; Magar, N.; J, K.; M, S.; A.P., P.; Laha, G. S.; LV, S. R.; Barbadikar, K. M.; Raman, M. S.; Patel, H. K.; Maganti, S. M.; Sonti, R. V.
10.1101/2023.10.10.561791 — plant biology — Posted on 2023-11-02
4734 Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma
Nejo, T.; Wang, L.; Leung, K. K.; Wang, A.; Lakshmanachetty, S.; Gallus, M.; Kwok, D. W.; Hong, C.; Chen, L. H.; Carrera, D. A.; Zhang, M. Y.; Stevers, N. O.; Maldonado, G. C.; Yamamichi, A.; Watchmaker, P.; Naik, A.; Shai, A.; Phillips, J. J.; Chang, S. M.; Wiita, A. P.; Wells, J. A.; Costello, J. F.; Diaz, A. A.; Okada, H.
10.1101/2023.10.26.564156 — cancer biology — Posted on 2023-11-02
4735 The brittle star genome illuminates the genetic basis of animal appendage regeneration
Parey, E.; Ortega-Martinez, O.; Delroisse, J.; Piovani, L.; Czarkwiani, A.; Dylus, D.; Arya, S.; Dupont, S.; Thorndyke, M.; Larsson, T.; Johannesson, K.; Buckley, K. M.; Martinez, P.; Oliveri, P.; Marletaz, F.
10.1101/2023.10.30.564762 — evolutionary biology — Posted on 2023-11-01
4737 Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning surrogate
Gherman, I. M.; Rees-Garbutt, J. P.; Pang, W.; Abdallah, Z. S.; Gorochowski, T. E.; Grierson, C. S.; Marucci, L.
10.1101/2023.10.30.564402 — bioengineering — Posted on 2023-11-01
4739 Non-canonical ORFs are an important source of tumor-specific antigens in a liver cancer meta-cohort
E. Camarena, M.; Theunissen, P.; Ruiz Egozcue, M.; Ruiz-Orera, J.; Calvo-Serra, B.; Castelo, R.; Sarobe, P.; Fortes, P.; Perera-Bel, J.; Alba, M. M.
10.1101/2023.10.30.564375 — genomics — Posted on 2023-11-01
4741 Specific sensory neurons and insulin-like peptides modulate food type-dependent oogenesis and fertilization in Caenorhabditis elegans
Mishra, S.; Dabaja, M.; Akhlaq, A.; Pereira, B.; Marbach, K.; Rovcanin, M.; Chandra, R.; Caballero, A.; de Abreu, D. F.; Ch'ng, Q.; Alcedo, J.
10.1101/2022.08.31.506073 — developmental biology — Posted on 2023-11-01
4742 Ipl1-controlled attachment maturation regulates Mps1 association with its kinetochore receptor
Pleuger, R.; Cozma, C.; Hohoff, S.; Denkhaus, C.; Dudziak, A.; Kaschani, F.; Musacchio, A.; Vetter, I. R.; Westermann, S.
10.1101/2023.10.30.564738 — cell biology — Posted on 2023-11-01
4746 Patient phenotypes and their relation to TNFα signaling and immune cell composition in critical illness and autoimmune disease
Krishna, V.; Banie, H.; Conceicao-Neto, N.; Murata, Y.; Verbrugge, I.; Trifonov, V.; Martinez, R.; Murali, V.; Lee, Y.-c.; May, R. D.; Najera, I.; Fowler, A.; Li, C. K. F.
10.1101/2023.10.30.564631 — immunology — Posted on 2023-11-01
4748 Enzymatic assembly of small synthetic genes with repetitive elements
Nguyen, M. T. A.; Gobry, M. V.; Vallina, N. S.; Pothoulakis, G.; Andersen, E. S.
10.1101/2022.11.23.517630 — synthetic biology — Posted on 2023-11-01
4749 Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter
Baker, G. J.; Novikov, E.; Zhao, Z.; Vallius, T.; Davis, J. A.; Lin, J.-R.; Muhlich, J. L.; Mittendorf, E. A.; Santagata, S.; Guerriero, J. L.; Sorger, P. K.
10.1101/2023.11.01.565120 — pathology — Posted on 2023-11-01
4750 Differential Activity of MAPK signalling Defines Fibroblast Subtypes in Pancreatic Cancer
Veghini, L.; Pasini, D.; Delfino, P.; Corbo, V.; Fiorini, E.; Lupo, F.; Bevere, M.; Luchini, C.; Lawlor, R. T.; Scarpa, A.; Cheung, P. F.-Y.; Siveke, J. T.; Vicentini, C.; Filippini, D.; D'Agosto, S. L.; Carbone, C.; Behrens, D.; Biffi, G.; Neander, C.; Fang, R.
10.1101/2023.10.30.564752 — cancer biology — Posted on 2023-11-01
4754 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging
Mazzellat, l.; Mangeat, T.; Li, H.; Creff, J.; Rogez, B.; Martins, C.; Galland, F.; Allain, M.; Giroussens, G.; Idier, J.; Labouesse, S.; Sentenac, A.; LeGoff, L.
10.1101/2023.10.30.564754 — bioengineering — Posted on 2023-11-01
4755 Walking (and talking) the plank: Dual-task performance costs in a virtual balance-threatening environment
Raffegeau, T. E.; Brinkerhoff, S. A.; Clark, M.; McBride, A. D.; Williams, A. M.; Fino, P. C.; Fawver, B.
10.1101/2023.10.29.564612 — bioengineering — Posted on 2023-11-01
4758 Cultivated Robusta coffee meets wild Coffea canephora: Evidence of cultivated-wild hybridisation in the Democratic Republic of the Congo
Depecker, J.; Verleysen, L.; Bollen, R.; Asimonyio, J.; Hatangi, Y.; Kambale, J.-L.; Mwanga Mwanga, I.; Ebele, T.; Dheda, B.; Stoffelen, P.; Ruttink, T.; Vandelook, F.; Honnay, O.
10.1101/2023.10.30.564669 — ecology — Posted on 2023-11-01
4760 Safety Assessment of Intravenous Injection of Rat Embryonic Proteome Extract for in-vivo Regenerative Therapies
DARSI, S. R. P.; Kandula, S. k.; barani, K. K.; Pasupulati, A. K.; chikatla, s. s.; Darsi, S. K.; Kamireddy, A. R.; Barra, R. R.; Devarasetty, A. K.; Surampudi, S.
10.1101/2023.10.30.563384 — developmental biology — Posted on 2023-11-01
4761 Superovulation and aging perturb oocyte-granulosa cell communication
Daugelaite, K.; Lacour, P.; Winkler, I.; Koch, M.-L.; Schneider, A.; Schneider, N.; Tolkachov, A.; Nguyen, X. P.; Vilkaite, A.; Rehnitz, J.; Goncalves, A.; Odom, D.
10.1101/2023.10.30.563978 — developmental biology — Posted on 2023-11-01
4762 Precision-Cut Liver Slices as an ex vivo model to evaluate antifibrotic therapies for liver fibrosis and cirrhosis
Wang, Y.; Leaker, B.; Qiao, G.; Sojoodi, M.; Eissa, I. R.; Epstein, E. T.; Eddy, J.; Dimowo, O.; Mullen, A. C.; Lauer, G. M.; Chung, R. T.; Qadan, M.; Lanuti, M.; Fuchs, B. C.; Tanabe, K. K.
10.1101/2023.10.30.564772 — cell biology — Posted on 2023-11-01
4763 Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment
Owens, S. M.; Sifford, J.; Li, G.; Murdock, S.; Salinas, E.; Manzano, M.; Ghosh, D.; Stumhofer, J. S.; Forrest, J. C.
10.1101/2023.10.31.563188 — microbiology — Posted on 2023-11-01
4764 Human CD127 negative ILC2s show immunological memory
Matha, L.; Krabbendam, L.; Martinez-Hoyer, S.; Heesters, B.; Golebski, K.; Kradolfer, C. M. A.; Ghaedi, M.; Ma, J.; Stadhouders, R.; Bachert, C.; Cardell, L. O.; Nan, Z.; Holtappels, G.; Helgers, L. C.; Geijtenbeek, T. B. H.; Coquet, J. M.; Takei, F.; Spits, H.; Martinez-Gonzalez, I.
10.1101/2023.10.29.564625 — immunology — Posted on 2023-11-01
4765 NEUTROPHILS ARE INDISPENSABLE FOR ADVERSE CARDIAC REMODELING IN HEART FAILURE
Rokosh, G.; Prabhu, S. S.; Antipenko, S. V.; Hamid, T.; Ismahil, M. A.; Mayfield, N.; Gunzer, M.; Jinno, M.
10.1101/2023.10.31.565035 — immunology — Posted on 2023-11-01
4766 Role of finger movement kinematics in friction perception at initial contact with smooth surfaces
Afzal, H. M. N.; Dullinac, S. d. B. d.; Loutit, A.; Shea, H. O.; Martinez Ulloa, P. M. U.; Khamis, H.; Vickery, R. M.; Wiertlewski, M.; Redmond, S. J.; Birznieks, I.
10.1101/2023.10.29.564644 — neuroscience — Posted on 2023-11-01
4767 The laminar pattern of proprioceptive activation in human primary motor cortex
Knudsen, L.; Guo, F.; Huang, J.; Blicher, J. U.; Lund, T. E.; Zhou, Y.; Zhang, P.; Yang, Y.
10.1101/2023.10.29.564658 — neuroscience — Posted on 2023-11-01
4770 Molecular epidemiology of Cercospora leaf spot on resistant and susceptible sugar beet hybrids
Chen, C.; Keunecke, H.; Neu, E.; Kopisch-Obuch, F. J.; McDonald, B. A.; Stapley, J.
10.1101/2023.10.30.564591 — pathology — Posted on 2023-11-01
4771 Critical capillary waves of biomolecular condensates
Shimobayashi, S. F.; Konishi, K.; Ackerman, P. J.; Taniguchi, T.; brangwynne, C. P.
10.1101/2023.10.29.564316 — biophysics — Posted on 2023-11-01
4773 Advancing Cell Therapies: Single-Cell Profiling, Generation, Expansion, and Gene Delivery in Rhesus Macaque Plasma B Cells
Cheng, R. Y.-H.; Kreuser, S.; Dahl, N.; Honaker, Y.; Soligalla, R.; Lopez, C.; Rawlings, D. J.; James, R. G.
10.1101/2023.10.29.564645 — bioengineering — Posted on 2023-11-01
4776 From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways
Gu, S.; Shao, Y.; Rehm, K.; Bigler, L.; Zhang, D.; He, R.; Shao, J.; Jousset, A.; Friman, V.-P.; Wei, Z.; Kummerli, R.; Li, Z.
10.1101/2023.10.30.564663 — genomics — Posted on 2023-11-01
4782 Nucleolus and centromere TSA-Seq reveals variable localization of heterochromatin in different cell types
Kumar, P.; Gholamalamdari, O.; Zhang, Y.; Zhang, L.; Vertii, A.; van Schaik, T.; Peric-Hupkes, D.; Sasaki, T.; Gilbert, D. M.; van Steensel, B.; Ma, J.; Kaufman, P. D.; Belmont, A. S.
10.1101/2023.10.29.564613 — cell biology — Posted on 2023-11-01
4783 The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.
Tsukuda, S.; Harris, J.; Magri, A.; Balfe, P.; Wing, P. A.; Siddiqui, A.; McKeating, J.
10.1101/2023.10.31.564956 — molecular biology — Posted on 2023-11-01
4784 Desiccated cyanobacteria serve as efficient plasmid DNA carrier in space flight
Kakouridis, A.; Diamond, S.; Eng, T.; Mills, H. J.; Gamez-Holzhaus, O.; Summers, M. L.; Garcia-Pichel, F.; Mukhopadhyay, A.
10.1101/2023.10.31.564425 — microbiology — Posted on 2023-11-01
4785 Pyrimidine salvage in Toxoplasma gondii as a target for new treatment
Elati, H. A. A.; Goerner, A. L.; Martorelli di Genova, B.; Sheiner, L.; De Koning, H. P.
10.1101/2023.11.01.565095 — microbiology — Posted on 2023-11-01
4786 A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha and Betaproteobacteria
Espaillat, A.; Alvarez, L.; Torrens, G.; ter Beek, J.; Miguel-Ruano, V.; Irazoki, O.; Gago, F.; Hermoso, J. A.; Berntsson, R. P.-A.; Cava, F.
10.1101/2023.10.31.564931 — microbiology — Posted on 2023-11-01
4787 SARS-CoV-2 infection leads to sustained testicular injury and functional impairments in K18 hACE2 mice
Giannakopoulos, S.; Ward, M. A.; Bakse, J.; Pak, J. H.; Nerurkar, V. R.; Tallquist, M. D.; Verma, S.
10.1101/2023.10.31.565042 — microbiology — Posted on 2023-11-01
4788 Unusual 1-3 peptidoglycan cross-links in Acetobacteriaceae are made by L,D-transpeptidases with a catalytic domain distantly related to YkuD domains
MESNAGE, S.; Alaman-Zarate, M. G.; Rady, B. J.; Evans, C. A.; Pian, B.; Greetham, D.; Marecos-Ortiz, S.; Dickman, M. J.; Lidbury, I. D.; Barstow, B.
10.1101/2023.10.31.563487 — microbiology — Posted on 2023-11-01
4789 Extremely oligotrophic and complex organic compounds degrading microaerobic bacteria from Arabian Sea oxygen minimum zone sediments
Sarkar, J.; Mondal, M.; Bhattacharya, S.; Chatterjee, S.; Mondal, N.; Dutta, S.; N, S.; Peketi, A.; Mazumdar, A.; Ghosh, W.
10.1101/2023.10.31.564988 — microbiology — Posted on 2023-11-01
4792 The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase
Zhou, Y.; Phelps, G. A.; Mangrum, M. M.; McLeish, J.; Phillips, E. K.; Lou, J.; Ancajas, C. F.; Rybak, J. M.; Oelkers, P. M.; Best, M. D.; Lee, R.; Reynolds, T. B. B.
10.1101/2023.11.01.565123 — microbiology — Posted on 2023-11-01
4793 Non-consecutive enzyme interactions within TCA cycle supramolecular assembly regulate carbon-nitrogen metabolism
Jasinska, W.; Dindo, M.; Correa, S. M.; Serohijos, A.; Laurino, P.; Brotman, Y.; Bershtein, S.
10.1101/2023.11.01.565101 — microbiology — Posted on 2023-11-01
4794 A proteogenomic pipeline for the analysis of protein biosynthesis errors in the human pathogen Candida albicans.
Correia, I.; Oliveira, C.; Reis, A.; Guimaraes, A. R.; Aveiro, S.; Domingues, P.; Bezerra, A. R.; Vitorino, R.; Moura, G.; Santos, M. A. S.
10.1101/2023.10.31.564356 — microbiology — Posted on 2023-11-01
4796 The bioreactor microbiome of mass cultivated marine diatoms for industrial carbon capture and utilization
Aalto, N. J.; Giaver, I. H.; Eriksen, G. K.; Israelsen, L.; Krsmanovic, S.; Petters, S.; Bernstein, H. C.
10.1101/2023.11.01.565100 — microbiology — Posted on 2023-11-01
4798 Hidradenitis suppurativa patients exhibit a distinctive and highly individualized skin virome
Jansen, D.; Bens, L.; Wagemans, J.; Green, S. I.; Hillary, T.; Vanhoutvin, T.; Van Laethem, A.; Vermeire, S.; Sabino, J.; Lavigne, R.; Matthijnssens, J.
10.1101/2023.10.30.564771 — microbiology — Posted on 2023-11-01
4799 Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease
Tu, J. C.; Millar, P. R.; Strain, J. F.; Eck, A.; Adeyemo, B.; Daniels, A.; Karch, C.; Huey, E. D.; McDade, E.; Day, G. S.; Yakushev, I.; Hassenstab, J.; Morris, J.; Llibre-Guerra, J. J.; Ibanez, L.; Jucker, M.; Mendez, P. C.; Bateman, R. J.; Perrin, R. J.; Benzinger, T.; Jack, C. R.; Betzel, R.; Ances, B. M.; Eggebrecht, A. T.; Gordon, B. A.; Wheelock, M. D.; Dominantly Inherited Alzheimer Network,
10.1101/2023.10.29.564633 — neuroscience — Posted on 2023-11-01
4800 Proteomic evidence of astrocytic dysfunction in the olfactory bulb of depressed suicides
Rahimian, R.; Perlman, K.; Fakhfouri, G.; Mpai, R.; Richard, V. R.; Hercher, C.; Penney, L.; Davoli, M. A.; Nagy, C.; Zahedi, R. P.; Borchers, C. H.; Giros, B.; Turecki, G.; Mechawar, N.
10.1101/2023.10.29.564604 — neuroscience — Posted on 2023-11-01
4801 Altered astrocytic and microglial homeostasis characterizes a decreased proinflammatory state in bipolar disorder
Amosse, Q.; Tournier, B. B.; Badina, A. M.; Marchand-Maillet, L.; Abjean, L.; Lengacher, S.; Fancy, N.; Smith, A. M.; Leung, Y.-Y.; Santer, V.; Garibotto, V.; Owen, D. R.; Piguet, C.; Ceyzeriat, K.; Tsartsalis, S.; Millet, P.
10.1101/2023.10.29.564621 — neuroscience — Posted on 2023-11-01
4803 Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma
Ramirez, C. F.; Taranto, D.; Ando-Kuri, M.; de Groot, M. H.; Tsouri, E.; Huang, Z.; de Groot, D.; Kluin, R. J.; Kloosterman, D. J.; Verheij, J.; Xu, J.; Vegna, S.; Akkari, L.
10.1101/2023.10.29.564350 — cancer biology — Posted on 2023-11-01
4804 A human pluripotent stem cell-based somitogenesis model using microfluidics
Liu, Y.; Kim, Y. S.; Xue, X.; Kobayashi, N.; Sun, S.; Yang, Q.; Pourquie, O.; Fu, J.
10.1101/2023.10.29.564399 — bioengineering — Posted on 2023-11-01
4805 Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds
Julio, A. R.; Shikwana, F.; Truong, C.; Burton, N. R.; Dominguez, E.; Turmon, A.; Cao, J.; Backus, K.
10.1101/2023.10.30.564067 — biochemistry — Posted on 2023-11-01
4806 Balanced Interplay Between Hsp110, Hsp70 and Class B J-Domain Protein Improves Aggregate Disassembly
Sztangierska, W.; Wyszkowski, H.; Pokornowska, M.; Rychlowski, M.; Liberek, K.; Klosowska, A.
10.1101/2023.10.31.564973 — biochemistry — Posted on 2023-11-01
4807 Cryo-EM structure of the Spo11 core complex bound to DNA
Yu, Y.; Wang, J.; Liu, K.; Zheng, Z.; Arter, M.; Bouuaert, C. C.; Pu, S.; Patel, D. J.; Keeney, S.
10.1101/2023.10.31.564985 — biochemistry — Posted on 2023-11-01
4808 Covalent Degrader of the Oncogenic Transcription Factor β-Catenin
Gowans, F. A.; Forte, N.; Hatcher, J.; Wang, Y.; Poblano, B. E. A.; Wertz, I. E.; Nomura, D. K.
10.1101/2023.10.31.565018 — biochemistry — Posted on 2023-11-01
4814 Ectopic transcription due to inappropriately inherited histone methylation may interfere with the ongoing function of terminally differentiated cells
Rodriguez, J. D.; Reeves, M.; Wang, H.-L.; Chavez, J.; Rastogi, R.; Chavez, S.; Chadha, M.; Hill, E. J.; Corces, V. G.; Schmeichel, K.; Katz, D. J.
10.1101/2023.10.29.564525 — developmental biology — Posted on 2023-11-01
4815 Stability of DNA-Methylation Profiles of Biological Aging in Children and Adolescents
deSteiguer, A. J.; Raffington, L.; Sabhlok, A.; Tanksley, P. T.; Harden, K. P.; Tucker-Drob, E. M.
10.1101/2023.10.30.564766 — developmental biology — Posted on 2023-11-01
4817 Assessment of The Broad-Spectrum Host Targeting Antiviral Efficacy of Halofuginone Hydrobromide in Human Airway, Intestinal and Brain Organoid Models.
Garcia-Rodriguez, I.; Moreni, G.; Capendale, P. E.; Aknouch, I.; Mulder, L. A.; Johannesson, N.; Vieira de Sa, R.; Freeze, E.; van Eijk, H.; Koen, G.; Wolthers, K. C.; Pajkrt, D.; Sridhar, A.; Calitz, C.
10.1101/2023.11.01.565121 — microbiology — Posted on 2023-11-01
4820 Incorporation of 5 methylcytidine alleviates innate immune response to self-amplifying RNA vaccine
Komori, M.; Morey, A. L.; Quinones-Molina, A. A.; Fofana, J.; Romero, L.; Peters, E.; Matsuda, K.; Gummuluru, S.; Smith, J. F.; Akahata, W.; Akiyama, H.
10.1101/2023.11.01.565056 — immunology — Posted on 2023-11-01
4821 SARS-CoV-2 spike protein induces the cytokine release syndrome by stimulating T cells to produce more IL-2
Niu, C.; Liang, T.; Chen, Y.; Zhu, S.; Zhou, L.; Chen, N.; Qian, L.; Wang, Y.; Li, M.; Zhou, X.; Cui, J.
10.1101/2023.11.01.565098 — immunology — Posted on 2023-11-01
4822 Extending the applicability of optically pumped magnetoencephalography toward early human life
Corvilain, P.; Wens, V.; Bourguignon, M.; Capparini, C.; Fourdin, L.; Ferez, M.; Feys, O.; De Tiege, X.; Bertels, J.
10.1101/2023.10.28.564455 — neuroscience — Posted on 2023-11-01
4823 Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression
Privitera, M.; von Ziegler, L. M.; Floriou-Servou, A.; Duss, S. N.; Zhang, R.; Waag, R.; Leimbacher, S.; Sturman, O.; Roessler, F.; Heylen, A.; Vermeiren, Y.; Van Dam, D.; De Deyn, P. P.; Germain, P.-L.; Bohacek, J.
10.1101/2023.02.02.526661 — neuroscience — Posted on 2023-11-01
4824 Rolling 2D Bioelectronic film into 1D: a Suturable Long-term Implantable Soft Microfiber
Xie, R.; Yu, Q.; Li, D.; Han, X.; Xu, X.; Huang, J.; Yan, W.; Zhou, X.; Deng, X.; Tian, Q.; Li, Q.; Li, H.; Zheng, H.; Li, G.; Han, F.; Xu, T.; Liu, Z.
10.1101/2023.10.02.560392 — neuroscience — Posted on 2023-11-01
4830 Soil health is linked to primary productivity across Europe
Romero, F.; Labouyrie, M.; Orgiazzi, A.; Ballabio, C.; Panagos, P.; Jones, A.; Tedersoo, L.; Bahram, M.; Smith, L. C.; Guerra, C. A.; Lugato, E.; Eisenhauer, N.; Delgado-Baquerizo, M.; van der Heijden, M. G. A.
10.1101/2023.10.29.564603 — ecology — Posted on 2023-11-01
4831 Noncanonical circRNA biogenesis driven by alpha and gamma herpesviruses
Dremel, S. E.; Koparde, V. N.; Arbuckle, J. H.; Hogan, C. H.; Kristie, T. M.; Krug, L. T.; Conrad, N. K.; Ziegelbauer, J. M.
10.1101/2022.07.08.499347 — microbiology — Posted on 2023-11-01
4833 Gardenin A improves cognitive and motor function in A53T-α-syn mice
Hack, W.; Gladen-Kolarsky, N.; Chatterjee, S.; Lang, Q.; Maitra, U.; Ciesla, L.; Gray, N. E.
10.1101/2023.10.27.564401 — neuroscience — Posted on 2023-11-01
4834 A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer's disease-related molecules in the hippocampus
Han, X.; Li, P. H.; Wang, S.; Sanchez, M.; Aggarwal, S.; Blakely, T.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Wu, Y.; Aly, F.; Bay, S.; Delatour, B.; Lafaye, P.; Pfister, H.; Wei, D.; Jain, V.; Ploegh, H.; Lichtman, J.
10.1101/2023.10.24.563674 — neuroscience — Posted on 2023-11-01
4835 TMS-EEG shows mindfulness meditation is associated with an altered excitation/inhibition balance in the dorsolateral prefrontal cortex
Humble, G.; Geddes, H.; Baell, O.; Payne, J. E.; Hill, A. T.; Chung, S. W.; Emonson, M.; Caldwell, B.; Fitzgerald, P. B.; Cash, R.; Bailey, N.
10.1101/2023.10.27.564494 — neuroscience — Posted on 2023-11-01
4838 Leveraging gene correlations in single cell transcriptomic data
Silkwood, K.; Dollinger, E.; Gervin, J.; Atwood, S.; Nie, Q.; Lander, A. D.
10.1101/2023.03.14.532643 — systems biology — Posted on 2023-11-01
4839 ATG8 delipidation is dispensable for plant autophagy
Holla, S.; Zou, Y.; Sabljic, I.; Ohlsson, J. A.; Leong, J. X.; Ballhaus, F.; Krebs, M.; Schumacher, K.; Uestuen, S.; Dagdas, Y.; Bozhkov, P.; Minina, E. A.
10.1101/2023.08.23.554513 — plant biology — Posted on 2023-11-01
4842 Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism
Shaw, A.; Craig, J. M.; Amiri, H.; Kim, J.; Upton, H. E.; Pimentel, S. C.; Huang, J. R.; Marqusee, S.; Gundlach, J. H.; Collins, K.; Bustamante, C. J.
10.1101/2023.04.05.535757 — biophysics — Posted on 2023-11-01
4843 Temperature-driven coordination of circadian transcriptome regulation
Xu, B.; Hwangbo, D.-S.; Saurabh, S.; Rosensweig, C.; Allada, R.; Kath, W.; Braun, R.
10.1101/2023.10.27.563979 — bioinformatics — Posted on 2023-11-01
4846 A novel phylogenomics pipeline reveals complex pattern of reticulate evolution in Cucurbitales
Ortiz, E. M.; Hoewener, A.; Shigita, G.; Raza, M.; Maurin, O.; Zuntini, A.; Forest, F.; Baker, W. J.; Schaefer, H.
10.1101/2023.10.27.564367 — bioinformatics — Posted on 2023-11-01
4852 Acute effects of psilocybin on the dynamics of gaze fixations during visual aesthetic perception
Muller, S.; Cavanna, F.; de la Fuente, L. A.; Bruno, N.; D'Amelio, T.; Pallavicini, C.; Tagliazucchi, E.
10.1101/2023.10.27.564413 — animal behavior and cognition — Posted on 2023-11-01
4853 Pitfalls in performing genome-wide association studies on ratio traits
McCaw, Z. R.; Dey, R.; Somineni, H.; Amar, D.; Mukherjee, S.; Sandor, K.; insitro Research Team, ; Karaletsos, T.; Koller, D.; Davey Smith, G.; MacArthur, D.; O'Dushlaine, C.; Soare, T. W.
10.1101/2023.10.27.564385 — genetics — Posted on 2023-11-01
4854 Detection, characterization, and phylogenetic analysis of a near-whole genome sequence of a novel astrovirus in an endemic Malagasy fruit bat, Rousettus madagascariensis
Horigan, S.; Kistler, A. L.; Ranaivoson, H. C.; Andrianiaina, A.; Andry, S.; Kettenburg, G.; Raharinosy, V.; Randriambolamanantsoa, T. H.; Tato, C.; Lacoste, V.; Heraud, J.-M.; Dussart, P.; Brook, C. E.
10.1101/2023.10.27.564436 — evolutionary biology — Posted on 2023-11-01
4855 Formation of hemiclonal reproduction and hybridogenesis in Pelophylax water frogs studied with species-specific cytogenomic probes
Choleva, L.; Dolezalkova-Kastankova, M.; Labajova, V.; Sember, A.; Altmanova, M.; Luksikova, K.; Chung Volenikova, A.; Dalikova, M.; Nguyen, P.; Pustovalova, E.; Fedorova, A.; Dedukh, D.
10.1101/2023.10.29.564577 — evolutionary biology — Posted on 2023-11-01
4858 RETINOID ORPHAN RECEPTOR GAMMA T (RORgT) PROMOTES INFLAMMATORY EOSINOPHILIA BUT IS DISPENSABLE FOR INNATE IMMUNE-MEDIATED COLITIS
Torres-Huerta, A.; Ruley-Haase, K.; Reed, T.; Boger-May, A.; Rubadeux, D.; Mayer, L.; Rajashekara, A. M.; Hiller, M.; Frech, M.; Roncagli, C.; Pedersen, C.; Camacho, M. C.; Hollmer, L.; English, L.; Kane, G.; Boone, D.
10.1101/2023.10.27.564391 — immunology — Posted on 2023-11-01
4859 LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness.
Pallavicini, I.; Frasconi, T. M.; Ceccaci, E.; Tiberti, S.; Nava Lauson, C. B.; Preto, E.; Bigogno, A. O.; Mangione, M.; Sala, E.; Iannacone, M.; Kuka, M.; Nezi, L.; Minucci, S.; Manzo, T.
10.1101/2023.10.27.564395 — immunology — Posted on 2023-11-01
4863 Hyperactive PI3Kinase delta enables long distance regeneration of the rat corticospinal tract
Karova, K.; Polcanova, Z.; Suchankova, S.; Knight, L.; Nieuwenhuis, B.; Holota, R.; Herynek, V.; Urdzikova, L. M.; Turecek, R.; Kwok, J. C. F.; Verhaagen, J.; Eva, R.; Fawcett, J. W.; Jendelova, P.
10.1101/2023.10.27.564182 — neuroscience — Posted on 2023-11-01
4865 Activity in the reticulospinal tract scales with handgrip force in humans
Danielson, T. L.; Gould, L.; DeFreitas, J. M.; MacLennan, R. J.; Borowsky, R.; Farthing, J. P.; Andrushko, J. W.
10.1101/2023.10.27.563544 — neuroscience — Posted on 2023-11-01
4868 Medial temporal lobe functional network architecture supports sleep-related emotional memory processing in older adults
Chappel-Farley, M. G.; Adams, J. N.; Betzel, R. N.; Janecek, J. C.; Sattari, N. S.; Berisha, D. E.; Meza, N. J.; Niknazar, H.; Kim, S.; Dave, A.; Chen, I. Y.; Lui, K. K.; Neikrug, A. B.; Benca, R. M.; Yassa, M. A.; Mander, B. A.
10.1101/2023.10.27.564260 — neuroscience — Posted on 2023-11-01
4872 BRAIDing receptors for cell specific targeting
Chen, H.; Lee, S.-J.; Li, R.; Sura, A.; Suen, N.; Dilip, A.; Pomogov, Y.; Vuppalapaty, M.; Suen, T. T.; Lu, C.; Post, Y.; Li, Y.
10.1101/2023.07.18.549566 — synthetic biology — Posted on 2023-11-01
4874 Adjusted vascular contractility relies on integrity of progranulin pathway: Insights into mitochondrial function
Singh, S.; Bruder-Nascimento, A.; Costa, R. M.; Alves, J. V.; Bharathi, S.; Goetzman, E. S.; Bruder-Nascimento, T.
10.1101/2023.10.27.564485 — pharmacology and toxicology — Posted on 2023-11-01
4875 Oncogenic RAS-Pathway Activation Drives Oncofetal Reprogramming and Creates Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
Hartmann, M.; Schoenung, M.; Rajak, J.; Maurer, V.; Hai, L.; Bauer, K.; Hakobyan, M.; Staeble, S.; Langstein, J.; Jardine, L.; Roelz, R.; Bohler, S.; Khabirova, E.; Maag, A.-H.; Vonficht, D.; Lebrecht, D.; Bernt, K. M.; Tan, K.; Chen, C.; Alikarami, F.; Boch, T.; Flore, V.; Lutsik, P.; Milsom, M. D.; Raffel, S.; Buske, C.; Haas, S.; Haniffa, M.; Mallm, J.-P.; Behjati, S.; Bonder, M.-J.; Froehling, S.; Niemeyer, C. M.; Hey, J.; Flotho, C.; Plass, C.; Erlacher, M.; Schlesner, M.; Lipka, D. B.
10.1101/2023.10.27.563754 — cancer biology — Posted on 2023-11-01
4876 The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.
de Oliveira Alves, N.; Dalmasso, G.; Nikitina, D.; Vaysse, A.; Ruez, R.; Ledoux, L.; Pedron, T.; Bergstein, E.; Boulard, O.; Autier, L.; Allam, S.; Motreff, L.; Sauvanet, P.; Letourneur, D.; Gagniere, J.; Pezet, D.; Godfraind, C.; Salzet, M.; Lemichez, E.; Najjar, I.; Malabat, C.; Monot, M.; Mestivier, D.; Barnich, N.; Fournier, I.; Kennedy, S.; Mettouchi, A.; Bonnet, R.; Sobhani, I.; Chamaillard, M.
10.1101/2023.03.13.523827 — cancer biology — Posted on 2023-11-01
4879 A polydiolcitrate-MoS2 composite for 3D printing Radio-opaque, Bioresorbable Vascular Scaffolds
Szydlowska, B. M.; Ding, Y.; Moore, C.; Cai, Z.; Torres-Castanedo, C. G.; Jones, E.; Hersam, M. C.; Sun, C.; Ameer, G. A.
10.1101/2023.10.27.564364 — bioengineering — Posted on 2023-11-01
4882 Modern wheat breeding selection synergistically improves above- and below-ground traits
Zhao, P.; Liu, Z.; Shi, X.; Hou, W.; Cheng, M.; Liu, Y.; Simmonds, J.; Ji, W.; Uauy, C.; Xu, S.; Wang, X.
10.1101/2023.10.27.564104 — genetics — Posted on 2023-11-01
4883 Characterization of an Osmr Conditional Knockout Mouse Model
Schwartz, L.; Saxl, R. L.; Stearns, T.; Trowbridge, J. J.
10.1101/2023.10.27.564474 — genetics — Posted on 2023-11-01
4884 Genome-wide DNA methylation changes in human spermatogenesis
Siebert-Kuss, L. M.; Dietrich, V.; Di Persio, S.; Bhaskaran, J.; Stehling, M.; Cremers, J.-F.; Sandmann, S.; Varghese, J.; Kliesch, S.; Schlatt, S.; Vaquerizas, J. M.; Neuhaus, N.; Laurentino, S.
10.1101/2023.10.27.564382 — genetics — Posted on 2023-11-01
4887 What is Known, Unknown, and Needed to be Known about Damage Caused by Wild Pigs
VerCauteren, K. C.; Pepin, K.; Cook, S.; McKee, S.; Pagels, A.; Kohen, K.; Messer, I.; Glow, M. P.; Snow, N.
10.1101/2023.10.27.564386 — ecology — Posted on 2023-11-01
4888 Localized Rift Valley Fever Virus Persistence Depends on a High Transovarial Transmission Fraction
Rostal, M. K.; Prentice, J.; Ross, N.; Kemp, A.; Thompson, P.; Anyamba, A.; Cleaveland, S.; Cordel, C.; Msimang, V.; Jansen van Vuren, P.; Haydon, D.; Karesh, W. B.; Paweska, J.; Matthews, L.
10.1101/2023.10.27.564291 — ecology — Posted on 2023-11-01
4889 The majority of Germany's small agricultural streams are in poor ecological status
von Goenner, J.; Groening, J.; Grescho, V.; Neuer, L.; Haensch, V. G.; Laue, B.; Molsberger-Lange, E.; Wilharm, E.; Liess, M.; Bonn, A.
10.1101/2023.10.27.564349 — ecology — Posted on 2023-11-01
4890 The PHB Granule Biogenesis Pathway in Caulobacter
de Koning, E. A.; Panjalingam, M.; Tran, J.; Eckhart, M. R.; Dahlberg, P. D.; Shapiro, L.
10.1101/2023.07.06.548030 — molecular biology — Posted on 2023-11-01
4891 Soquelitinb, A selective inhibitor of interleukin-2-inducible kinase (ITK), is active in several murine models of T cell-mediated inflammatory disease
Hsu, L.-Y.; Rosenbaum, J. T.; Lindner, S.; Allanore, Y.; Cauvet, A.; Pawar, R. D.; Li, D.; Van Den Brink, M.; Miller, R. A.
10.1101/2023.10.27.564296 — immunology — Posted on 2023-11-01
4892 MetaGate: Interactive Analysis of High-Dimensional Cytometry Data with Meta Data Integration
Ask, E. H.; Tschan-Plessl, A.; Hoel, H. J.; Kolstad, A.; Holte, H.; Malmberg, K.-J.
10.1101/2023.10.27.564454 — immunology — Posted on 2023-11-01
4893 Immunosuppression is a conserved driver of tuberculosis susceptibility
Kotov, D. I.; Lee, O. V.; Ji, D. X.; Jaye, D. L.; Suliman, S.; Gabay, C.; Vance, R. E.
10.1101/2023.10.27.564420 — immunology — Posted on 2023-11-01
4896 Structural basis of epitope recognition by anti-alpha synuclein antibodies MJFR14-6-4-2
Lieknina, I.; Pantelejevs, T.; Lends, A.; Reimer, L.; Jaudzems, K.; El-Turabi, A.; Gram, H.; Jensen, P. H.; Tars, K.
10.1101/2023.10.27.564328 — neuroscience — Posted on 2023-11-01
4901 Coenzyme-Protein Interactions since Early Life
Sanchez Rocha, A. C.; Makarov, M.; Pravda, L.; Novotny, M.; Hlouchova, K.
10.1101/2023.10.28.563965 — bioinformatics — Posted on 2023-11-01
4903 3D-printed, Citrate-based Bioresorbable Vascular Scaffolds for Coronary Artery Angioplasty
Ding, Y.; Warlick, L.; Chen, M.; Taddese, E.; Collins, C.; Fu, R.; Duan, C.; Wang, X.; Ware, H.; Sun, C.; Ameer, G.
10.1101/2023.10.27.564432 — bioengineering — Posted on 2023-11-01
4904 RNA activities of trans species: RNA from the sperm of the father of an autistic child programs glial cells and behavioral disorders in mice.
Yilmaz Sukranli, Z.; Korkmaz Bayram, K.; Mehmetbeyoglu, E.; Doganyigit, Z.; Beyaz, F.; Sener, E. F.; Taheri, S.; Ozkul, Y.; Rassoulzadegan, M.
10.1101/2023.10.27.564312 — animal behavior and cognition — Posted on 2023-11-01
4908 B cell-stromal cell cross talk drives mesenteric lymph node eosinophilia during intestinal helminth infection
Bessell, E.; Finlay, R.; James, L. K.; Ludewig, B.; Harris, N.; Hepworth, M. R.; Dubey, L. K.
10.1101/2023.10.28.564531 — immunology — Posted on 2023-11-01
4909 Individual variations in reward-seeking adaptability emerge among isogenic mice living in a micro-society and predict their response to nicotine
Fayad, S. L.; Reynolds, L. M.; Torquet, N.; Tolu, S.; Mondoloni, S.; Nguyen, C.; Justo, R.; Didienne, S.; Debray, N.; Viollet, C.; Raynaud, L.; Layadi, Y.; Hannesse, B.; Ana Marta, C.; Topilko, T.; Renier, N.; Mourot, A.; Marti, F.; Faure, P.
10.1101/2023.10.28.564522 — neuroscience — Posted on 2023-11-01
4910 Nicotine in adolescence freezes dopamine circuits in an immature state
Reynolds, L. M.; Gulmez, A.; Fayad, S. L.; Campos, R. C.; Rigoni, D.; Nguyen, C.; Le Borgne, T.; Topilko, T.; Rajot, D.; Franco, C.; Marti, F.; Heck, N.; Mourot, A.; Renier, N.; Barik, J.; Faure, P.
10.1101/2023.10.28.564518 — neuroscience — Posted on 2023-11-01
4914 Excessive cortical beta oscillations are associated with slow-wave sleep dysfunction in mild parkinsonism
Verma, A. K.; Nandakumar, B.; Acedillo, K.; Yu, Y.; Marshall, E.; Schneck, D.; Fiecas, M.; Wang, J.; MacKinnon, C. D.; Howell, M. J.; Vitek, J. L.; Johnson, L. A.
10.1101/2023.10.28.564524 — neuroscience — Posted on 2023-11-01
4916 Leveraging Julia's automated differentiation and symbolic computation to increase spectral DCM flexibility and speed
Hofmann, D.; Chesebro, A. G.; Rackauckas, C.; Mujica-Parodi, L. R.; Friston, K.; Edelman, A.; Strey, H. H.
10.1101/2023.10.27.564407 — neuroscience — Posted on 2023-11-01
4917 Multi-echo Acquisition and Thermal Denoising Advances Infant Precision Functional Imaging
Moser, J.; Koirala, S.; Madison, T.; Labonte, A. K.; Morales Carrasco, C.; Feczko, E.; Moore, L. A.; Ahmed, W.; Myers, M. J.; Yacoub, E.; Trevo-Clemmens, B.; Larsen, B.; Laumann, T. O.; Nelson, S. M.; Vizioli, L.; Sylvester, C. M.; Fair, D. A.
10.1101/2023.10.27.564416 — neuroscience — Posted on 2023-11-01
4921 A dynamic bactofilin cytoskeleton cooperates with an M23 endopeptidase to control bacterial morphogenesis
Pöhl, S.; Osorio-Valeriano, M.; Cserti, E.; Harberding, J.; Hernandez-Tamayo, R.; Biboy, J.; Sobetzko, P.; Vollmer, W.; Graumann, P. L.; Thanbichler, M.
10.1101/2023.02.27.530196 — microbiology — Posted on 2023-11-01
4922 Neutrophil-derived complement factor P induces cytotoxicity in basal-like cells via caspase 3/7 activation in pancreatic cancer
Kishore, U.; Varghese, P.; Mangogna, A.; Klein, L.; Tu, M.; Urbach, L.; Qiu, M.; Nicolle, R.; Murugaiah, V.; Beirag, N.; Roth, S.; Pedersen, D.; Sim, R.; Ellenrieder, V.; Andersen, G. R.; Bulla, R.; Singh, S.
10.1101/2023.10.28.564512 — immunology — Posted on 2023-11-01
4923 The modified elevated gap interaction test: A novel paradigm to assess social preference.
De Zeeuw, C. I.; Yu, S.-y.; Chen, J.; Van Hoogstraten, W. S.; Van den Maagdenberg, A. M. J. M.; Bosman, L. W. J.; Kros, L.
10.1101/2023.10.30.564718 — neuroscience — Posted on 2023-11-01
4924 Sleep-state dependent cerebellar processing in adult mice
Canto, C. B.; Bauer, S.; Hoogland, T. M.; Hoedemaker, H. H.; Geelen, C.; Loyola, S.; Hernandez, P. M.; De Zeeuw, C. I.
10.1101/2023.10.30.564769 — neuroscience — Posted on 2023-11-01
4926 Age-induced midbrain-striatum assembloids model early phenotypes of Parkinsons disease
Barmpa, K.; Saraiva, C.; Gomez-Giro, G.; Gabassi, E.; Spitz, S.; Rodriguez Gatica, J. E.; Antony, P.; Robertson, G.; Papastefanaki, F.; Kubitscheck, U.; Salti, A.; Ertl, P.; Matsas, R.; Edenhofer, F.; Schwamborn, J. C.
10.1101/2023.10.28.564305 — neuroscience — Posted on 2023-11-01
4928 The origin of intestinal cancer in the context of inflammation
Verhagen, M. P.; Joosten, R.; Schmitt, M.; Valimaki, N.; Sacchetti, A.; Rajamaki, K.; Choi, J.; Procopio, P.; Silva, S.; van der Steen, B.; van den Bosch, T. P. P.; Seinstra, D.; Doukas, M.; Augenlicht, L. H.; Aaltonen, L. A.; Fodde, R.
10.1101/2023.10.02.560432 — cancer biology — Posted on 2023-11-01
4929 ALDH1A3-acetaldehyde re-wires neural crest stem cell and high metabolism states to potentiate melanoma heterogeneity
Lu, Y.; Travnickova, J.; Badonyi, M.; Rambow, F.; Coates, A.; Khan, Z.; Marques, J.; Murphy, L.; Garcia-Martinez, P.; Marais, R.; Louphrasitthiphol, P.; Kriegsheim, A. V.; Marsh, J. A.; Pavet, V.; Sansom, O. J.; Illingworth, R. S.; Patton, E. E.
10.1101/2023.10.28.564337 — cancer biology — Posted on 2023-11-01
4930 Identification and functional analysis of eRNA markers for hepatocellular carcinoma based on high-throughput data
Chen, Z.; Chen, J.; Zhang, R.; Zhu, Y.; Feng, D.; Han, H.; Li, T.; Liu, X.; Wang, X.; Wang, Z.; Wang, H.; Wang, L.; Li, B.; Li, J.
10.1101/2023.10.28.564513 — cancer biology — Posted on 2023-11-01
4931 ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions
Durand, S.; TANG, Y.; Pommier, R. M.; Benboubker, V.; Grimont, M.; Boivin, F.; Barbollat, L.; Cumunel, E.; Dupeuble, F.; Eberhardt, A.; Plaschka, M.; Dalle, S.; CARAMEL, J.
10.1101/2023.02.10.526467 — cancer biology — Posted on 2023-11-01
4932 H3-OPT: Accurate prediction of CDR-H3 loop structures of antibodies with deep learning
Tian, B.; Chen, H.; Fan, X.; Zhu, S.; Pei, Y.; Zhang, X.; Zhang, X.; Liu, L.; Qian, F.
10.1101/2023.08.19.553933 — bioinformatics — Posted on 2023-11-01
4935 Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations
Chandrasekaran, S. N.; Cimini, B. A.; Goodale, A.; Miller, L.; Kost-Alimova, M.; Jamali, N.; Doench, J. G.; Fritchman, B.; Skepner, A.; Melanson, M.; Kalinin, A. A.; Arevalo, J.; Haghighi, M.; Caicedo, J.; Kuhn, D.; Hernandez, D.; Berstler, J.; Shafqat-Abbasi, H.; Root, D.; Swalley, S. E.; Garg, S.; Singh, S.; Carpenter, A. E.
10.1101/2022.01.05.475090 — bioinformatics — Posted on 2023-11-01
4936 GENA-LM: A Family of Open-Source Foundational DNA Language Models for Long Sequences
Fishman, V.; Kuratov, Y.; Petrov, M.; Shmelev, A.; Shepelin, D.; Chekanov, N.; Kardymon, O.; Burtsev, M.
10.1101/2023.06.12.544594 — bioinformatics — Posted on 2023-11-01
4938 The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival
Dong, H.; Yang, J.; He, K.; Zheng, W.-B.; Lai, D.-H.; Liu, J.; Ding, H.-Y.; Wu, R.-B.; Brown, K. M.; Hide, G.; Lun, Z.-R.; Zhu, X.-Q.; Long, S.
10.1101/2023.06.06.543661 — microbiology — Posted on 2023-11-01
4940 Galectin-9 regulates dendritic cell contractility and migration via RhoA
Franken, G.; Cuenca-Escalona, J.; Stehle, I. F.; van Reijmersdal, V.; Gokhale, R. R.; Classens, R.; diBlasio, S.; Rodgers Furones, A.; Dolen, Y.; van Spriel, A.; Querol Cano, L.
10.1101/2023.10.30.564706 — immunology — Posted on 2023-11-01
4942 Mapping Cell-to-cell Interactions from Spatially Resolved Transcriptomics Data
Zhu, J. Z.; Wang, Y.; Chang, W. Y.; Malewska, A.; Napolitano, F.; Gahan, J. C.; Unni, N.; Zhao, M.; Wu, F.; Guo, L.; Zhao, Z.; Chen, D. Z.; Hannan, R.; Zhang, S.; Xiao, G.; Mu, P.; Hanker, A. B.; Strand, D.; Arteaga, C. L.; Desai, N.; Wang, X.; Xie, Y.; Wang, T.
10.1101/2023.09.18.558298 — bioinformatics — Posted on 2023-11-01
4943 Small variant benchmark from a complete assembly of X and Y chromosomes
Wagner, J.; Olson, N. D.; McDaniel, J.; Harris, L.; Pinto, B. J.; Jaspez, D.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Lorenzo-Salazar, J. M.; Flores, C.; Sahraeian, S. M. E.; Narzisi, G.; Byrska-Bishop, M.; Evani, U. S.; Xiao, C.; Lake, J. A.; Fontana, P.; Greenberg, C.; Freed, D.; Boutros, P. C.; Mootor, M. F. E.; Murray, L.; Shafin, K.; Carroll, A.; Sedlazeck, F. J.; Wilson, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2023.10.31.564997 — genomics — Posted on 2023-11-01
4944 Characterisation and Genetic Architecture of Major Depressive Disorder Subgroups Defined by Weight and Sleep Changes
Marshall, S.; Adams, M. J.; Evans, K. L.; Strawbridge, R. J.; Campbell, A.; Hayward, C.; McIntosh, A. M.; Thomson, P.
10.1101/2022.08.30.504498 — genomics — Posted on 2023-11-01
4945 Exploring phenotypic and genetic variability in hemp (Cannabis sativa)
Trubanova, N.; Pender, G.; McCabe, P. F.; Melzer, R.; Schilling, S.
10.1101/2023.11.01.565084 — plant biology — Posted on 2023-11-01
4948 Population level gene expression can repeatedly link genes to functions in maize
Torres-Rodriguez, J. V.; Li, D.; Turkus, J.; Newton, L.; Davis, J.; Lopez-Corona, L.; Ali, W.; Sun, G.; Mural, R. V.; Grzybowski, M. W.; Thompson, A. M.; Schnable, J. C.
10.1101/2023.10.31.565032 — plant biology — Posted on 2023-11-01
4949 DELLA Proteins Recruit the Mediator Complex Subunit MED15 to Co-activate Transcription in Land Plants
Hernandez-Garcia, J.; Serrano-Mislata, A.; Lozano-Quiles, M.; Urbez, C.; Nohales, M. A.; Blanco-Tourinan, N.; Peng, H.; Ledesma-Amaro, R.; Blazquez, M. A.
10.1101/2023.11.01.565078 — plant biology — Posted on 2023-11-01
4951 Chloroplasts lacking class I glutaredoxins are functional but show a delayed recovery of protein cysteinyl redox state after oxidative challenge
Bohle, F.; Rossi, J.; Tamanna, S. S.; Jansohn, H.; Schlosser, M.; Reinhardt, F.; Brox, A.; Bethmann, S.; Kopriva, S.; Trentmann, O.; Jahns, P.; Deponte, M.; Schwarzländer, M.; Trost, P.; Zaffagnini, M.; Meyer, A. J.; Müller-Schüssele, S. J.
10.1101/2023.10.31.564817 — plant biology — Posted on 2023-11-01
4952 Warm temperature suppresses plant systemic acquired resistance by intercepting the N-hydroxypipecolic acid immune pathway
Shields, A.; Yao, L.; Kim, J. H.; Mudher Abo Al-Timmen, W.; Li, S.; Marchetta, E.; Shivnauth, V.; Chen, T.; He, S. Y.; Xin, X.; Castroverde, C. D.
10.1101/2023.10.31.564368 — plant biology — Posted on 2023-11-01
4953 Imputation of cell-type specific expression using RNA-seq data from mixed cell populations
Lin, W.-Y.; Kartawinata, M.; Jebson, B. R.; Restuadi, R.; CLUSTER Consortium, ; Wedderburn, L. R.; Wallace, C.
10.1101/2023.09.11.556650 — bioinformatics — Posted on 2023-11-01
4954 Benchmarking of small and large variants across tandem repeats
English, A.; Dolzhenko, E.; Ziaei-Jam, H.; Olson, N. D.; Mckenzie, S.; De Coster, W.; Park, J.; Gu, B.; Wagner, J.; Eberle, M.; Gymrek, M.; Chaisson, M.; Zook, J. M.; Sedlazeck, F. J.
10.1101/2023.10.29.564632 — bioinformatics — Posted on 2023-11-01
4957 Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
Luo, Y.; Hao, H.; Wang, Z.; Ong, C.; Dutcher, R.; Xu, Y.; Liu, J.; Pedersen, L. C.; Xu, D.
10.1101/2023.07.26.550758 — cell biology — Posted on 2023-11-01
4959 Sleep consolidation potentiates skill maintenance
Solano, A.; Lerner, G.; Griffa, G.; Deleglise, A.; Caffaro, P.; Riquelme, L.; Perez-Chada, D.; Della-Maggiore, V.
10.1101/2023.10.26.564031 — neuroscience — Posted on 2023-11-01
4961 Sequence-ensemble-function relationships for disordered proteins in live cells
Emenecker, R. J.; Guadalupe, K.; Shamoon, N. M.; Sukenik, S.; Holehouse, A. S.
10.1101/2023.10.29.564547 — biophysics — Posted on 2023-11-01
4963 Chromosome-scale assembly of the African yam bean genome
Waweru, B.; Njaci, I.; Murungi, E.; Paliwal, R.; Muli, C.; Maranga, M.; Kaimenyi, D.; Lyimo, B.; Nigussie, H.; Ahadi, B.; Assefa, E.; Ishag, H.; Olomitutu, O.; Abberton, M.; Darby, C.; Uauy, C.; Yao, N.; Adewale, D.; Emmrich, P.; Domelevo Entfellner, J.-B.; Shorinola, O.
10.1101/2023.10.31.564964 — genomics — Posted on 2023-11-01
4965 A Simple Bias Reduction Algorithm for RNA Sequencing Datasets
Thron, C.; Bergom, H.; Boytim, E.; Roberts, M.; Hwang, J.; Jafari, F.
10.1101/2023.10.31.564992 — genomics — Posted on 2023-11-01
4967 piRNAs are regulators of metabolic reprogramming in stem cells
Rojas-Rios, P.; Chartier, A.; Enjolras, C.; Cremaschi, J.; Garret, C.; Boughlita, A.; Ramat, A.; Simonelig, M.
10.1101/2023.10.31.564965 — developmental biology — Posted on 2023-11-01
4968 Nanometer-scale views of visual cortex reveal anatomical features of primary cilia poised to detect synaptic spillover
Ott, C. M.; Torres, R.; Kuan, T.-S.; Kuan, A. T.; Buchanan, J.; Elabbady, L.; Seshamani, S.; Bodor, A. L.; Collman, F. C.; Bock, D. D.; Lee, W.-C. A.; Macarico da Costa, N.; Lippincott-Schwartz, J.
10.1101/2023.10.31.564838 — cell biology — Posted on 2023-11-01
4972 Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection
Moule, M. G.; Benjamin, A. B.; Burger, M. L.; Herlan, C.; Lebedev, M.; Lin, J. S.; Koster, K. J.; Wavare, N.; Adams, L. G.; Bräse, S.; Barron, A. E.; Cirillo, J. D.
10.1101/2023.10.30.564794 — microbiology — Posted on 2023-11-01
4974 Estimating multimodal brain variability in schizophrenia spectrum disorders: A worldwide ENIGMA study
Omlor, W.; Rabe, F.; Fuchs, S.; Cecere, G.; Homan, S.; Surbeck, W.; Kallen, N.; Georgiadis, F.; Spiller, T.; Seifritz, E.; Weickert, T.; Bruggemann, J.; Weickert, C.; Potkin, S.; Hashimoto, R.; Sim, K.; Rootes-Murdy, K.; Quide, Y.; Houenou, J.; Banaj, N.; Vecchio, D.; Piras, F.; Piras, F.; Spalletta, G.; Salvador, R.; Karuk, A.; Pomarol-Clotet, E.; Rodrigue, A.; Pearlson, G.; Glahn, D.; Tomecek, D.; Spaniel, F.; Skoch, A.; Kirschner, M.; Kaiser, S.; Kochunov, P.; Fan, F.-M.; Andreassen, O.; Westlye, L. T. A.; Berthet, P.; Calhoun, V.; Howells, F. M.; Uhlmann, A.; Scheffler, F.; Stein, D.; Iase
10.1101/2023.09.22.559032 — neuroscience — Posted on 2023-11-01
4975 Deciphering Drought Response Mechanisms: Transcriptomic Insights from Drought-Tolerant and Drought-Sensitive Wheat (Triticum aestivum L.) Cultivars
CEVHER-KESKIN, B.; YILDIZHAN, Y.; SEKMEN-CETINEL, A. H.; SEZERMAN, O. U.; OZER, B.; FAYETORBAY, R.; ONARICI, S.; TURKAN, I.; TOR, M.
10.1101/2023.10.26.563210 — plant biology — Posted on 2023-11-01
4976 Simulation of adaptive immune receptors and repertoires with complex immune information to guide the development and benchmarking of AIRR machine learning
Chernigovskaya, M.; Pavlovic, M.; Kanduri, C.; Gielis, S.; Robert, P. A.; Scheffer, L.; Slabodkin, A.; Haff, I. H.; Meysman, P.; Yaari, G.; Sandve, G. K.; Greiff, V.
10.1101/2023.10.20.562936 — bioinformatics — Posted on 2023-11-01
4977 Soft extracellular matrix drives an endoplasmic reticulum stress-dependent S quiescence underlying molecular traits of pulmonary basal cells
Laval, P.-A.; Piecyk, M.; Le Guen, P.; Ilie, M.; Fauvre, J.; Coste, I.; Renno, T.; Aznar, N.; Hadji, C.; Migdal, C.; Duret, C.; Bertolino, P.; Ferraro-Peyret, C.; Nicolas, A.; Chaveroux, C.
10.1101/2023.08.18.552093 — cell biology — Posted on 2023-11-01
4978 Polyethylene glycol (PEG)-associated immune responses triggered by clinically relevant lipid nanoparticles in rats
Wang, H.; Wang, Y.; Yuan, C.; Xu, X.; Zhou, W.; Huang, Y.; Lu, H.; Zheng, Y.; Luo, G.; Shang, J.; Sui, M.
10.1101/2022.11.24.516986 — immunology — Posted on 2023-11-01
4980 Uncoupling of synaptic loss from amyloid burden by an Alzheimer's disease protective variant of PLCγ2.
Bevan, R.; Maguire, E.; Phillips, T.; Simonazzi, E.; Vassileva, M.; Williams, J.; Taylor, P.
10.1101/2023.09.22.558987 — neuroscience — Posted on 2023-11-01
4981 Gene Therapy for Cardiomyopathy associated with Duchenne Muscular Dystrophy in a Pig Model
Baehr, A.; Hoppmann, P.; Bozoglu, T.; Stirm, M.; Luksch, I.; Ziegler, T.; Hornaschewitz, N.; Shresta, S.; Shashikadze, B.; Stöckl, J. B.; Raad, N.; Blum, H.; Krebs, S.; Fröhlich, T.; Baumgartner, C.; Nowak-Imialek, M.; Walter, M.; Weber, C.; Engelhardt, S.; Moretti, A.; Klymiuk, N.; Wurst, W.; Laugwitz, K. L.; Hajjar, R. J.; Wolf, E.; Kupatt, C.
10.1101/2023.10.02.560452 — physiology — Posted on 2023-11-01
4982 Cell-type-specific efferocytosis determines functional plasticity of alveolar macrophages
Better, J.; Wetstein, M.; Estiri, M.; Malainou, C.; Ferrero, M. R.; Langelage, M.; Kuznetsova, I.; Vazquez-Armendariz, I.; Kimmig, L.; Mansouri, S.; Savai, R.; Wilhelm, J.; Alexopoulos, I.; Sommer, N.; Herold, S.; Matt, U.
10.1101/2023.03.07.528464 — immunology — Posted on 2023-11-01
4984 Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA
Reddy, N. A.; Zvolanek, K. M.; Moia, S.; Caballero-Gaudes, C.; Bright, M. G.
10.1101/2023.07.19.549746 — neuroscience — Posted on 2023-11-01
4985 Effects of Gene Dosage and Development on Subcortical Nuclei Volumes in Individuals with 22q11.2 Copy Number Variations
Schleifer, C. H.; O'Hora, K. P.; Fung, H.; Xu, J.; Robinson, T.-A.; Wu, A. S.; Kushan-Wells, L.; Ching, C. R. K.; Bearden, C. E.
10.1101/2023.10.31.564553 — neuroscience — Posted on 2023-11-01
4987 An integrated approach to identify sex-specific genes, transcription factors, and pathways in Alzheimer's disease
Lopez-Cerdan, A.; Andreu, Z.; Hidalgo, M. R.; Porlan, A.; Pozo-Morales, M.; de la Iglesia-Vaya, M.; Mikozami, A.; Guerini, F. R.; Garcia-Garcia, F.
10.1101/2023.09.05.556293 — neuroscience — Posted on 2023-11-01
4990 New information triggers prospective codes to adapt for flexible navigation
Prince, S. M.; Yassine, T. A.; Katragadda, N.; Roberts, T. C.; Singer, A. C.
10.1101/2023.10.31.564814 — neuroscience — Posted on 2023-11-01
4992 Lignin Composites with Sustained Oxygenation and Reactive Oxygen Species-Scavenging Improve Neovascularization and Healing of Diabetic Wounds
Padon, B. W.; Olutoye, O. O.; Short, W. D.; Kaul, A. A.; Yutzy, L. D.; Faruk, F.; Keswani, S. S.; Jung, O. S.; Kogan, P.; Yu, L.; Li, H.; Jung, J. P.; Balaji, S.
10.1101/2022.06.18.496670 — bioengineering — Posted on 2023-11-01
4993 The ghost of selection past: evolution and conservation relevance of the kakapo color polymorphism
Urban, L.; Santure, A. W.; Uddstrom, L.; Digby, A.; Vercoe, D.; Eason, D.; Crane, J.; Kakapo Recovery Team, ; Wylie, M. J.; Davis, T.; LeLec, M. F.; Guhlin, J.; Poulton, S.; Slate, J.; Alexander, A.; Fuentes-Cross, P.; Dearden, P. K.; Gemmell, N. J.; Azeem, F.; Weyland, M.; Schwefel, H. G. L.; van Oosterhout, C.; Morales, H. E.
10.1101/2023.09.25.559367 — genomics — Posted on 2023-11-01
4994 ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication
Espada, C. E.; da Rocha, E. L.; Ricciardi-Jorge, T.; dos Santos, A. A.; Soares, Z. G.; Malaquias, G.; Patricio, D. d. O.; Kozlova, E. G.; dos Santos, P. F.; Bordignon, J.; Sanford, T. J.; Fajardo, T.; Sweeney, T.; Bafica, A.; Mansur, D. S.
10.1101/784678 — immunology — Posted on 2023-11-01
4995 The role of microRNAs to understand sex-based differences in Alzheimer's disease
Llera-Oyola, J.; Carceller, H.; Andreu, Z.; Hidalgo, M. R.; Soler-Saez, I.; Gordillo, F.; Porlan, A.; Pozo-Morales, M.; Roson, B.; de la Iglesia, M.; Mancuso, R.; Guerini, F. R.; Mizokami, A.; Garcia-Garcia, F.
10.1101/2023.08.24.554586 — neuroscience — Posted on 2023-11-01
4996 Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesis
Thornton, M. A.; Futia, G. L.; Stockton, M. E.; Budoff, S. A.; Ramirez, A. N.; Ozbay, B.; Tzang, O.; Kilborn, K.; Poleg-Polsky, A.; Restrepo, D.; Gibson, E. A.; Hughes, E. G.
10.1101/2023.10.29.564636 — neuroscience — Posted on 2023-11-01