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Archive, 2024-05

2 Time-series sewage metagenomics can separate the seasonal, human-derived and environmental microbial communities, holding promise for source-attributed surveillance
Becsei, A.; Fuschi, A.; Otani, S.; Kant, R.; Weinstein, I.; Alba, P.; Steger, J.; Visontai, D.; Brinch, C.; de Graaf, M.; Schapendonk, C. M. E.; Battisti, A.; De Cesare, A.; Oliveri, C.; Troja, F.; Vapalahti, O.; Pasquali, F.; Banyai, K.; Mako, M.; Pollner, P.; Merlotti, A.; Koopmans, M.; Csabai, I.; Remondini, D.; Aarestrup, F. M.; Munk, P.
10.1101/2024.05.30.596588 — microbiology — Posted on 2024-05-31
3 Transfer of IgG from Long COVID patients induces symptomology in mice
Chen, H.-J.; Appelman, B.; Willemen, H.; Bos, A.; Prado, J.; Geyer, C. E.; Silva Santos Ribeiro, P.; Versteeg, S.; Larsen, M. D.; Schuchner, E.; Bomers, M. M. K.; Lavell, A. H. A.; Amsterdam UMC COVID-19 biobank, ; Charlton, B.; Wust, R.; Wiersinga, W. J.; van Vugt, M.; Vidarsson, G.; Eijkelkamp, N.; den Dunnen, J.
10.1101/2024.05.30.596590 — immunology — Posted on 2024-05-31
4 Disruption of Immune Responses By Type I Diabetes Exacerbates SARS-CoV-2 Mediated Lung Injury
Kass Gergi, S.; Zhao, G.; Wong, J.; Weiner, A. I.; Adam Tzivelekidis, S.; Gentile, M. E.; Mendoza, M.; Holcomb, N. P.; Li, X.; Singh, M.; Vaughan, A. E.
10.1101/2024.05.31.596857 — immunology — Posted on 2024-05-31
5 mTOR inhibition in Q175 Huntington's disease model mice facilitates neuronal autophagy and mutant huntingtin clearance
Stavrides, P.; Goulbourne, C. N.; Peddy, J.; Huo, C.; Rao, M.; Khetarpal, V.; Marchionini, D. M.; Nixon, R. A.; Yang, D.-S.
10.1101/2024.05.29.596471 — pathology — Posted on 2024-05-30
7 Time-resolved coupling between connectome harmonics and subjective experience under the psychedelic DMT
Vohryzek, J.; Luppi, A.; Atasoy, S.; Deco, G.; Timmermann, C.; Carhart-Harris, R. L.; Kringelbach, M. L.
10.1101/2024.05.30.596410 — neuroscience — Posted on 2024-05-31
8 Behavioral impairments are linked to neuroinflammation in mice with Cerebral Cavernous Malformation disease
Lopez-Ramirez, M. A.; Offenberger, J.; Chen, B.; Rossitto, L.-A.; Conaboy, L.; Gallego-Gutierrez, H.; Nelsen, B.; Frias-Anaya, E.; Gonzalez, D. J.; Anagnostaras, S.
10.1101/2024.05.29.596485 — animal behavior and cognition — Posted on 2024-05-31
9 Variable rates of SARS-CoV-2 evolution in chronic infections
Smith, E.; Hamilton, W. L.; Warne, B.; Walker, E. R.; Jahun, A. S.; Hosmillo, M.; ISARIC Consortium, ; Gupta, R. K.; Goodfellow, I.; Gkrania-Klotsas, E.; Torok, M. E.; Illingworth, C. J. R.
10.1101/2024.05.31.596818 — evolutionary biology — Posted on 2024-05-31
12 Loss of the mitochondrial carrier, SLC25A1, during embryogenesis induces a unique senescence program controlled by p53
Kasprzyk-Pawelec, A.; Tan, M.; Rahhal, R.; McIntosh, A.; Fernandez, H.; Mosaoa, R.; Jiang, L.; Pearson, G. W.; Glasgow, E.; Vockley, J.; Albanese, C.; Avantaggiati, M. L.
10.1101/2023.07.18.549409 — developmental biology — Posted on 2024-05-31
14 Exploring evolution to enhance mutational stability prediction
Hermans, P.; Tsishyn, M.; Schwersensky, M.; Rooman, M.; Pucci, F.
10.1101/2024.05.28.596203 — bioinformatics — Posted on 2024-05-31
15 Structural characterization and inhibition of the interaction between ch-TOG and TACC3
Shelford, J.; Burgess, S. G.; Rostkova, E.; Richards, M. W.; Tiede, C.; Fielding, A. J.; Daviter, T.; Tomlinson, D. C.; Calabrese, A. N.; Pfuhl, M.; Bayliss, R.; Royle, S. J.
10.1101/2024.05.31.596836 — cell biology — Posted on 2024-05-31
18 Linear β-1,2-glucans trigger immune hallmarks and disease resistance in plants
Fuertes-Rabanal, M.; Largo-Gosens, A.; Fischer, A.; Munzert, K. S.; Carrasco-Lopez, C.; Sanchez-Vallet, A.; Engelsdorf, T.; Melida, H.
10.1101/2024.05.30.596602 — plant biology — Posted on 2024-05-31
20 Single-cell dissection of prognostic architecture and immunotherapy response in Helicobacter pylori infection associated gastric cancer
Zhang, X.; Zhang, G.; Sang, S.; Fei, Y.; Cao, X.; Song, W.; Liu, F.; Che, J.; Tao, H.; Wang, H.; Zhang, L.; Guan, Y.; Rong, S.; Pei, L.; Yao, S.; Wang, Y.; Zhang, M.; Liu, C.
10.1101/2024.05.31.596846 — cancer biology — Posted on 2024-05-31
21 Structural dynamics of the intrinsically disordered linker region of cardiac troponin T
Cubuk, J.; Greenberg, L.; Greenberg, A. E.; Emenecker, R. J.; Stuchell-Brereton, M. D.; Holehouse, A. S.; Soranno, A. J.; Greenberg, M. J.
10.1101/2024.05.30.596451 — biophysics — Posted on 2024-05-31
22 Design of a multi-epitope camel mastitis vaccine candidate using a reverse vaccinology approach
murungi, e.; langat, n.; masila, e.; onywera, r.; ogali, i.; gicheru, n.; wesonga, h.; maichomo, m.
10.1101/2024.05.26.595936 — bioinformatics — Posted on 2024-05-31
27 The Chemokine Receptor CCR8 is Not a High-affinity Receptor for the Human Chemokine CCL18
Hussain, K.; Lim, H.; Devkota, S. R.; Kemp-Harper, B.; Lane, J. R.; Canals, M.; Pease, J. E.; Stone, M. J.
10.1101/2024.05.30.596614 — immunology — Posted on 2024-05-31
28 Real-time optimization to enhance noninvasive cortical excitability assessment in the human dorsolateral prefrontal cortex
Parmigiani, S.; Cline, C. C.; Sarkar, M.; Forman, L.; Truong, J.; Ross, J. M.; Gogulski, J.; Keller, C. J.
10.1101/2024.05.29.596317 — neuroscience — Posted on 2024-05-31
29 Working memory enhancement using real-time phase-tuned transcranial alternating current stimulation
Haslacher, D.; Cavallo, A.; Reber, P.; Kattein, A.; Thiele, M.; Nasr, K.; Hashemi, K.; Sokoliuk, R.; Thut, G.; Soekadar, S.
10.1101/2024.05.31.596854 — neuroscience — Posted on 2024-05-31
30 Retinoblastoma-related (RBR) has both canonical and non-canonical regulatory functions during thermo-morphogenic responses in Arabidopsis seedlings
Shiekh, R.; Nagy, F.; Kaszler, N.; Domonkos, I.; Gombos, M.; Molnar, E.; Pettko-Szandtner, A.; Bogre, L.; Feher, A.; Magyar, Z.
10.1101/2024.05.28.596227 — plant biology — Posted on 2024-05-31
31 Catalytically inactive subgroup VIII receptor-like cytoplasmic kinases regulate the immune-triggered oxidative burst in Arabidopsis thaliana
Goncalves Dias, M.; Dharmasena, T.; Gonzalez-Ferrer, C.; Maika, J. E.; Rodriguez Gallo, M. C.; Miguel, V. N.; Dou, R.; Bredow, M.; Siegel, K. R.; Uhrig, R. G.; Simon, R.; Monaghan, J.
10.1101/2024.05.30.596543 — plant biology — Posted on 2024-05-31
32 Deep homology and developmental constraint underlie the replicated evolution of grass awns
Erin, P. L.; Dana, M. R.; Michelle, H. M.; Joseph, G. P.; Devin, O. L.; Benedikt, N.; Bartlett, M. E.
10.1101/2024.05.30.596325 — plant biology — Posted on 2024-05-31
38 Functional conservation and divergence of Arabidopsis VENOSA4 and human SAMHD1 in DNA repair
Sarmiento-Manus, R.; Fontcuberta-Cervera, S.; Kawade, K.; Oikawa, A.; Tsukaya, H.; Quesada, V.; Micol, J. L.; Ponce, M. R.
10.1101/2024.05.27.596045 — plant biology — Posted on 2024-05-31
39 Physiological modeling into the metaverse of Mycobacterium Tuberculosis Beta CA inhibition mechanism
GiovannuzzI, S.; Shyamal, S. S.; Bhowmik, R.; Ray, R.; Manaithiya, A.; Carta, F.; Parkkila, S.; Aspatwar, A.; Supuran, C. T.
10.1101/2024.05.26.595948 — bioinformatics — Posted on 2024-05-31
40 Abscisic acid and GIGANTEA signalling converge to regulate the recruitment of CONSTANS to the FT promoter and activate floral transition
Robustelli Test, A.; Perrella, G.; Colanero, S.; Landoni, B.; Sutti, A.; Korwin Krukowski, P.; Vellutini, E.; Castorina, G.; Galbiati, M.; Martignago, D.; Tonelli, C.; Kaiserli, E.; Conti, L.
10.1101/2024.05.29.595696 — plant biology — Posted on 2024-05-31
41 CLAVATA signalling shapes barley inflorescence architecture by controlling activity and determinacy of shoot apical and rachilla meristems
Vardanega, I.; Maika, J. E.; Demesa-Arevalo, E.; Lan, T.; Kirschner, G. K.; Imani, J.; Acosta, I. F.; Makowska, K.; Hensel, G.; Ranaweera, T.; Shiu, S.-H.; Schnurbusch, T.; von Korff Schmising, M.; Simon, R.
10.1101/2024.05.28.595952 — plant biology — Posted on 2024-05-31
44 Variation in spatial population structure in the Anopheles gambiae species complex
McCann, R. S.; Courneya, J.-P.; Donnelly, M.; Laufer, M. K.; Mzilahowa, T.; Stewart, K.; Miles, A.; Takala-Harrison, S.; O'Connor, T. D.; Ag1000G Consortium,
10.1101/2024.05.26.595955 — ecology — Posted on 2024-05-31
48 Upregulation of FasII underlies synergistic neuropathological and behavioral defects in a Drosophila model of myotonic dystrophy
Koon, A. C.; Yeung, K. Y. W.; Leong, L. I.; Chen, Z. S.; Peng, S. I.; Fung, J. M. S.; Wu, Y.; Armstrong, N. S.; Bargiela, A.; Moreno, N.; Poyatos, J.; Vilchez, J.; Magneron, P.; Huguet, A.; Brewer, C. K.; Beck, E. S.; Artero, R.; Gomes-Pereira, M.; Gourdon, G.; Budnik, V.; Frank, C. A.; McCabe, B. D.; Chan, H. Y. E.
10.1101/2024.05.26.595976 — neuroscience — Posted on 2024-05-31
49 Parental assigned chromosomes for cultivated cacao provides insights into genetic architecture underlying responses to Ceratobasidium theobromae
Tobias, P. A.; Downs, J.; Epaina, P.; Singh, G.; Park, R. F.; Edwards, R. J.; Brugman, E.; Zulkifli, A.; Muhammad, J.; Purwantara, A.; Guest, D. I.
10.1101/2024.05.26.595985 — plant biology — Posted on 2024-05-31
50 PTGS is dispensable for the initiation of epigenetic silencing of an active transposon in Arabidopsis
Trasser, M.; Bohl-Viallefond, G.; Barragan-Borrero, V.; Diezma-Navas, L.; Loncsek, L.; Nordborg, M.; Mari-Ordonez, A.
10.1101/2024.05.27.596030 — plant biology — Posted on 2024-05-31
56 High refresh rate display for natural monocular viewing in AOSLO psychophysics experiments
Moon, B.; Linebach, G.; Yang, A.; Jenks, S. K.; Rucci, M.; Poletti, M.; Rolland, J. P.
10.1101/2024.05.26.595808 — bioengineering — Posted on 2024-05-31
59 Signatures in domesticated beet genomes pointing at genes under selection in a sucrose-storing root crop
Dhiman, A. S.; Taliadoros, D.; Holtgrewe-Stukenbrock, E.; McGrath, J. M.; Emrani, N.; Jung, C.
10.1101/2024.05.27.596033 — genomics — Posted on 2024-05-31
61 Terrestrial ecosystems enhance root zones in response to intensified drought
Xi, Q.; Gao, H.; Wang-Erlandsson, L.; Dong, J.; Fenicia, F.; Savenije, H. H. G.; Hrachowitz, M.
10.1101/2024.05.26.595986 — ecology — Posted on 2024-05-31
62 Causal discovery in biodiversity-mediated social-ecological systems
Santos, M. J.; Zu, P.; Zuppinger-Dingley, D.; Eppinga, M. B.; Gupta, A.; Pennekamp, F.; Li, C.; Mayor, S.; Stefanini, C.; Tokumoto, Y.; van Moorsel, S. J.; Harpe, M.; Reader, M. O.; Mo, L.; Muccione, V.; Schuman, M. C.
10.1101/2024.05.26.595962 — ecology — Posted on 2024-05-31
69 Aggressive high-grade NF2 mutant meningiomas downregulate oncogenic YAP signaling via the upregulation of VGLL4 and FAT3/4.
Parrish, A. G.; Arora, S.; Thirmanne, H. N.; Rudoy, D.; Schmid, S.; Sievers, P.; Sahm, F.; Holland, E. C.; Szulzewsky, F.
10.1101/2024.05.30.596719 — molecular biology — Posted on 2024-05-31
72 Dynamics of EEG Microstates Change Across the Spectrum of Disorders of Consciousness
Manasova, D.; Sanz Perl, Y.; Bruno, N. M.; Valente, M.; Rohaut, B.; Tagliazucchi, E.; Naccache, L.; Raimondo, F.; Sitt, J. D.
10.1101/2024.05.30.596582 — neuroscience — Posted on 2024-05-31
75 Single neuron contributions to the auditory brainstem EEG
Kuokkanen, P. T.; Kraemer, I.; Koeppl, C.; Carr, C. E.; Kempter, R.
10.1101/2024.05.29.596509 — neuroscience — Posted on 2024-05-31
79 A Unified Framework for Systematic Curation and Evaluation of Aging Biomarkers
Ying, K.; Paulson, S.; Eames, A.; Tyshkovskiy, A.; Li, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Kosheleva, A.; Snyder, M. P.; Gobel, D.; Herzog, C.; Poganik, J. R.; Biomarker of Aging Consortium, ; Moqri, M.; Gladyshev, V. N.
10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-05-31
80 The endolysosomal phospholipid bis(monoacylglycero)phosphate is synthesized via intra- and extracellular pathways
Bulfon, D.; Breithofer, J.; Grabner, G. F.; Fawzy, N.; Pirchheim, A.; Wolinski, H.; Kolb, D.; Hartig, L.; Tischitz, M.; Zitta, C.; Bramerdorfer, G.; Lass, A.; Taschler, U.; Kratky, D.; Greimel, P.; Zimmermann, R.
10.1101/2024.05.28.596187 — biochemistry — Posted on 2024-05-31
85 Genomic and functional analysis of rmp locus variants in Klebsiella pneumoniae
Lam, M. M.; Salisbury, S. M.; Treat, L. P.; Wick, R. R.; Judd, L. M.; Wyres, K. L.; Brisse, S.; Walker, K. A.; Miller, V. L.; Holt, K. E.
10.1101/2024.05.28.596137 — genomics — Posted on 2024-05-31
86 Preventing CpG island hypermethylation in oocytes safeguards mouse development
Kawamura, Y. K.; Ozonov, E. A.; Papasaikas, P.; Kondo, T.; Nguyen, N. V.; Stadler, M. B.; Smallwood, S. A.; Koseki, H.; Peters, A. H. F. M.
10.1101/2024.05.29.595726 — genetics — Posted on 2024-05-31
87 Evolution of invertebrate Cdk4/6-Cdkn2 system
Yuki, S.; Sasaki, S.; Yamamoto, Y.; Murakami, F.; Sakata, K.; Araki, I.
10.1101/2024.05.26.595977 — evolutionary biology — Posted on 2024-05-31
88 Histone H2B isoform H2bc27 is expressed in the developing brain of mouse embryos
Egashira, S.; Maehara, K.; Tanaka, K.; Nakamura, M.; Takemoto, T.; Ohkawa, Y.; Harada, A.
10.1101/2024.05.28.596135 — developmental biology — Posted on 2024-05-31
91 STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm.
Weeks, S.; Pezic, D.; Dodel, M.; Shah, K.; Bhamra, A.; Surinova, S.; Henderson, S.; Sharp, T. V.; Mardakheh, F. K.; HADJUR, S.
10.1101/2024.05.31.595485 — cell biology — Posted on 2024-05-31
92 Single-cell transcriptional and epigenetic mapping reveals cellular and molecular mechanisms driving non-ischemic cardiac fibrosis
Krstevski, C.; Farrugia, G. E.; Hsu, i.; Dona, M. S. I.; Gaynor, T. L.; Cohen, C. D.; Harper, R. L.; Harrison, T. I.; Claridge, B.; Drack, A.; Lelliott, P.; Kiriazis, H.; Brown, A.; McMullen, J. R.; Donner, D. G.; Lal, S.; Greening, D. W.; Pinto, A. R.
10.1101/2024.05.09.593315 — cell biology — Posted on 2024-05-31
95 Subtleties in Clathrin Heavy Chain Binding Boxes provide selectivity among Adaptor Proteins of Budding Yeast
Defelipe, L.; Veith, K.; Burastero, O.; Kupriianova, T.; Bento, I.; Skruzny, M.; Koebel, K.; Uetrecht, C.; Thuenauer, R.; Garcia-Alai, M. M.
10.1101/2024.05.30.596561 — molecular biology — Posted on 2024-05-31
96 Development of non-β-Lactam covalent allosteric inhibitors targeting PBP2a in Methicillin-Resistant Staphylococcus aureus
Shin, W. S.; Benin, B. M.; Kharel, R.; Hillyer, T.; Sun, C.; Cmolik, A. M.; Kuebler, T.; Sham, Y. Y.; Bonomo, R. A.; Mighion, J.
10.1101/2024.05.29.596450 — microbiology — Posted on 2024-05-31
97 Carbapenem-induced β-lactamase-isoform expression trends in Acinetobacter baumannii
Shin, W. S.; Benin, B. M.; Hillyer, T.; Aguirre, N.; Sham, Y. Y.; Willard, B.
10.1101/2024.05.30.596663 — microbiology — Posted on 2024-05-31
98 Microbiota in the ptarmigan intestine - an Inuit delicacy and its potential in popular cuisine
Bjornsen, M.; Valeron, N. R.; Vasquez, D. P.; Velasco, E. M.; Hansen, A. J.; Hauptmann, A. L.
10.1101/2024.05.30.596617 — microbiology — Posted on 2024-05-31
100 2'-Fucosyllactose Inhibits Human Norovirus Replication in Human Intestinal Enteroids
Patil, K.; Ayyar, B. V.; Neill, F. H.; Bode, L.; Estes, M. K.; Atmar, R. L.; Ramani, S.
10.1101/2024.05.30.596597 — microbiology — Posted on 2024-05-31
101 Alpha-defensin binding expands human adenovirus tropism
Zhao, C.; Porter, J. M.; Burke, P. C.; Arnberg, N.; Smith, J. G.
10.1101/2024.05.30.596681 — microbiology — Posted on 2024-05-31
102 Periodic ER-plasma membrane junctions support long-range Ca2+ signal integration in dendrites
Benedetti, L.; Fan, R.; Weigel, A. V.; Moore, A. S.; Houlihan, P. R.; Kittisopikul, M.; Park, G.; Petruncio, A.; Hubbard, P. M.; Pang, S.; Xu, C. S.; Hess, H.; Saalfeld, S.; Rangaraju, V.; Clapham, D. E.; De Camilli, P.; Ryan, T. A.; Lippincott-Schwartz, J.
10.1101/2024.05.27.596121 — neuroscience — Posted on 2024-05-31
103 The diversity of SNCA transcripts in neurons, and its impact on antisense oligonucleotide therapeutics
Evans, J. R.; Gustavsson, E. K.; Doykov, I.; Murphy, D.; Virdi, G.; Lachica, J.; Rontgen, A.; Murtada, M. H.; Pang, C. W.; Macpherson, H.; Wernick, A. I.; Toomey, C. E.; Athauda, D.; Choi, M.; Hardy, J.; Wood, N. W.; Vendruscolo, M.; Mills, K.; Heywood, W.; Ryten, M.; Gandhi, S.
10.1101/2024.05.30.596437 — neuroscience — Posted on 2024-05-31
107 Genetic ablation of GABAB receptors from oligodendrocyte precursor cells protects against demyelination in the mouse spinal cord
Gobbo, D.; Rieder, P.; Fang, L.-P.; Buttigieg, E.; Schablowski, M.; Damo, E.; Bosche, N.; Dallorto, E.; May, P.; Bai, X.; Kirchhoff, F.; Scheller, A.
10.1101/2024.05.29.596385 — neuroscience — Posted on 2024-05-31
111 Predicting Suicide Risk in Bipolar Disorder patients from Lymphoblastoid Cell Lines genetic signatures
Sharma, O.; Nayak, R.; Mizrahi, L.; Rike, W. A.; Choudhary, A.; Hussein, Y.; Rosh, I.; Tripathi, U.; Shemen, A.; Squassina, A.; Alda, M.; Stern, S.
10.1101/2024.05.30.596645 — neuroscience — Posted on 2024-05-31
113 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action
Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.
10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-05-31
115 Enhancing lipid production in plant cells through high-throughput genome editing and phenotyping via a scalable automated pipeline
Dong, J.; Croslow, S.; Lane, S.; Castro, D.; Blanford, J.; Zhou, S.; Park, K. Y.; Burgess, S. J.; Root, M.; Cahoon, E. B.; Shanklin, J.; Sweedler, J. V.; Zhao, H.; Hudson, M.
10.1101/2024.05.29.596527 — synthetic biology — Posted on 2024-05-31
116 Mpox virus (MPXV) vertical transmission and fetal demise in a pregnant rhesus macaque model
Krabbe, N. P.; Mitzey, A. M.; Bhattacharya, S.; Razo, E. R.; Zeng, X.; Bekiares, N.; Moy, A.; Kamholz, A.; Karl, J. A.; Daggett, G.; VanSleet, G.; Morgan, T.; Capuano, S. V.; Simmons, H. A.; Basu, P.; Weiler, A. M.; O'Connor, D. H.; Friedrich, T. C.; Golos, T. G.; Mohr, E. L.
10.1101/2024.05.29.596240 — pathology — Posted on 2024-05-31
117 Aging represses lung tumorigenesis and alters tumor suppression
Shuldiner, E. G.; Karmakar, S.; Tsai, M. K.; Hebert, J. D.; Tang, Y. J.; Andrejka, L.; Wang, M.; Detrick, C. R.; Cai, H.; Tang, R.; Petrov, D. A.; Winslow, M. M.
10.1101/2024.05.28.596319 — cancer biology — Posted on 2024-05-31
118 Multi-omics data integration reveals molecular mechanisms of carfilzomib resistance in multiple myeloma
Malyutina, A.; Sergeev, P.; Huber, J.; Miettinen, J. J.; Bolomsky, A.; Bao, J.; Parsons, A. O.; Mueller, A.; Marella, N.; van Duin, M.; Ludwig, H.; Tang, J.; Heckman, C. A.
10.1101/2024.05.26.595929 — cancer biology — Posted on 2024-05-31
119 Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies
Morgenstern, T. J.; Darko-Boateng, A.; Afriyie, E.; Shanmugam, S. K.; Zou, X.; Choudhury, P.; Desai, M.; Kass, R. S.; Clarke, O. B.; Colecraft, H. M.
10.1101/2024.05.28.596281 — biophysics — Posted on 2024-05-31
122 Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
Blackwell, A. M.; Jami-Alahmadi, Y.; Nasamu, A. S.; Kudo, S.; Senoo, A.; Slam, C.; Tsumoto, K.; Wohlschlegel, J. A.; Caaveiro, J. M. M.; Goldberg, D. E.; Sigala, P. A.
10.1101/2024.05.30.596652 — biochemistry — Posted on 2024-05-31
125 Healthy human induced pluripotent stem cell-derived cardiomyocytes exhibit sex dimorphism even without the addition of hormones
Givens, S. E.; Andebrhan, A. A.; Schmuck, E. G.; Renaud, A.; Abrahante-Llorens, J. E.; Stanis, N.; Dutton, J. R.; Ogle, B. M.
10.1101/2024.05.29.596547 — cell biology — Posted on 2024-05-31
126 PEX14 acts as the interface linking optineurin to cell type-selective pexophagy
Li, H.; Chen, S.; Claes, Z.; Lismont, C.; Vandewinkel, B.; Hussein, M. A. F.; Costa, C. F.; Imberechts, D.; Liu, Y.; Vandenberghe, W.; Verhelst, S.; Baes, M.; Fransen, M.
10.1101/2024.05.31.596776 — cell biology — Posted on 2024-05-31
128 A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus
Ng, T. W.; Furuyama, W.; Wirchnianski, A. S.; Saavedra-Avila, N. A.; Johndrow, C. T.; Chandran, K.; Jacobs, W. R.; Marzi, A.; Porcelli, S. A.
10.1101/2024.05.28.595735 — immunology — Posted on 2024-05-31
136 CCR2 silencing in sensory neurons blocks bone cancer progression
Midavaine, E.; Cote, J.; Trepanier, A.; Kashem, S. W.; Dansereau, M.-A.; Longpre, J.-M.; Charbonneau, M.; Dubois, C.; Jacobi, A. M.; Rose, S. D.; Behlke, M. A.; Sarret, P.
10.1101/2024.05.29.596531 — neuroscience — Posted on 2024-05-31
141 Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity
Tian, G.; Bartas, K.; Hui, M.; Chen, L.; Vasquez, J.; Azouz, G.; Derdeyn, P.; Manville, R.; Ho, E.; Fang, A.; Li, Y.; Tyler, I.; Setola, V.; Aoto, J.; Abbott, G.; Beier, K.
10.1101/2024.05.29.596557 — neuroscience — Posted on 2024-05-31
142 Dynamic Gamma Modulation of Hippocampal Place Cells Predominates Development of Theta Sequences
Wang, N.; Wang, Y.; Guo, M.; Wang, L.; Wang, X.; Zhu, N.; Yang, J.; Wang, L.; Zheng, C.; Ming, D.
10.1101/2024.03.27.586908 — neuroscience — Posted on 2024-05-31
144 Fast adaptive super-resolution lattice light-sheet microscopy for rapid, long-term, near-isotropic subcellular imaging
Qiao, C.; Li, Z.; Wang, Z.; Lin, Y.; Liu, C.; Zhang, S.; Liu, Y.; Feng, Y.; Wang, X.; Dong, X.; Guo, J.; Jiang, T.; Wang, Q.; Dai, Q.; Li, D.
10.1101/2024.05.09.593386 — biophysics — Posted on 2024-05-31
147 Modification of Azithromycin to Mitigate its Arrest of Autophagy
Quarrington, R. D.; Sapula, S. A.; Lester, S. E.; Miller, M. M.; Munic Kos, V.; Kopp, B. T.; Jersmann, H. P.; Blencowe, A.; Roscioli, E.
10.1101/2024.04.25.591217 — biochemistry — Posted on 2024-05-31
148 SCAN1 mutant TDP1 blocks the repair of DSB induced by TOP1 activity during gene transcription and promotes genome reorganisations and cell death in quiescent cells
Rubio-Contreras, D.; Hidalgo-Garcia, D.; Angulo-Jimenez, C.; Granado-Calle, E.; Sabio-Bonilla, M.; Ruiz, J. F.; Herreros, F. G.
10.1101/2024.05.27.596066 — genetics — Posted on 2024-05-31
149 CoPheScan: phenome-wide association studies accounting for linkage disequilibrium
Manipur, I.; Reales, G.; Sul, J. H.; Shin, M. K.; Longerich, S.; Cortes, A.; Wallace, C.
10.1101/2023.06.29.546856 — genetics — Posted on 2024-05-31
151 Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.
Schwartz, I.; Budroni, V.; Meyenberg, M.; Hornegger, H.; Hacker, K.; Schwartz, S.; Hodakova, Z.; Grabarczyk, D. B.; Ehrmann, J.; Scinicariello, S.; Haselbach, D.; Menche, J.; Clausen, T.; Karagoez, E.; Versteeg, G. A.
10.1101/2024.04.23.590688 — cell biology — Posted on 2024-05-31
153 Visual detection of seizures in mice using supervised machine learning
Sabnis, G.; hession, l.; Mahoney, J. M.; Mobley, A.; Santos, M.; Kumar, V.
10.1101/2024.05.29.596520 — neuroscience — Posted on 2024-05-31
156 Dynamics of EEG Microstates Change Across the Spectrum of Disorders of Consciousness
Manasova, D.; Sanz Perl, Y.; Bruno, N. M.; Valente, M.; Rohaut, B.; Tagliazucchi, E.; Naccache, L.; Raimondo, F.; Sitt, J. D.
10.1101/2024.05.30.596582 — neuroscience — Posted on 2024-05-31
157 Self-Supervised Grid Cells Without Path Integration
Pettersen, M.; Schoyen, V. S.; Ostby, M. D.; Malthe-Sorenssen, A.; Lepperod, M. E.
10.1101/2024.05.30.596577 — neuroscience — Posted on 2024-05-31
159 Heterogeneous brain region-specific responses to astrocytic mitochondrial DNA damage in mice
Ayala, D. A.; Matarazzo, A.; Seaberg, B. L.; Patel, M.; Tijerina, E.; Matthews, C.; Bizi, G.; Brown, A.; Ta, A.; Rimer, M.; Srinivasan, R.
10.1101/2024.05.29.596517 — neuroscience — Posted on 2024-05-31
164 CellBin enables highly accurate single-cell segmentation for spatial transcriptomics
Li, M.; Liu, H.; Kang, Q.; Fang, S.; Zhang, J.; Teng, F.; Wang, D.; Cen, W.; Li, Z.; Feng, N.; Guo, J.; He, Q.; Wang, L.; Zheng, T.; Li, S.; Bai, Y.; Xie, M.; Bai, Y.; Liao, S.; Chen, A.; Brix, S.; Xu, X.; Zhang, Y.; Li, Y.
10.1101/2023.02.28.530414 — bioinformatics — Posted on 2024-05-31
170 A thalamic perspective of (un)consciousness in pharmacological and pathological states in humans
Szocs, D.; Lyu, D.; Luppi, A. I.; Coppola, P.; Woodrow, R.; Williams, G. B.; Allanson, J.; Pickard, J. D.; Owen, A. M.; Naci, L.; Menon, D. K.; Stamatakis, E. A.
10.1101/2024.05.30.596600 — neuroscience — Posted on 2024-05-31
171 Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
Cui, M.; Pan, X.; Fan, Z.; Ji, R.; Wu, S.; Wang, X.; Kong, X.; Wu, Z.; Song, W.; Yang, J.-X.; Zhang, H.; Zhang, H.; Ding, H.-L.; Cao, J.-L.
10.1101/2024.05.30.596721 — neuroscience — Posted on 2024-05-31
173 Towards an unbiased characterization of genetic polymorphism
Igolkina, A.; Vorbrugg, S.; Rabanal, F.; Liu, H.-J.; Ashkenazy, H.; Kornienko, A.; Fitz, J.; Collenberg, M.; Kubica, C.; Morales, A. M.; Jaegle, B.; Wrightsman, T.; Voloshin, V.; Llaca, V.; Nizhynska, V.; Reichardt, I.; Lanz, C.; Bemm, F.; Flood, P. J.; Nemomissa, S.; Hancock, A.; Guo, Y.-L.; Kersey, P.; Weigel, D.; Nordborg, M.
10.1101/2024.05.30.596703 — genomics — Posted on 2024-05-30
179 Pathobiology of the autophagy-lysosomal pathway in the Huntington's disease brain
Berg, M. J.; Veeranna, ; Rosa, C. M.; Kumar, A.; Mohan, P. S.; Stavrides, P.; Marchionini, D. M.; Yang, D.-S.; Nixon, R. A.
10.1101/2024.05.29.596470 — pathology — Posted on 2024-05-30
182 Differentiation of related events in hippocampus supports memory reinstatement in development
Varga, N. L.; Roome, H. E.; Molitor, R. J.; Martinez, L.; Hipskind, E. M.; Mack, M. L.; Preston, A. R.; Schlichting, M. L.
10.1101/2023.05.25.541743 — neuroscience — Posted on 2024-05-30
184 Visualization of Incrementally Learned Projection Trajectories for Longitudinal Data
Malepathirana, T. A.; Senanayake, D.; Gautam, V.; Engel, M.; Balez, R.; Lovelace, M.; Sundaram, G.; Heng, B.; Chow, S.; Marquis, C.; Guillemin, G.; Brew, B.; Jagadish, C.; Ooi, L.; Halgamuge, S.
10.1101/2022.11.25.515889 — bioinformatics — Posted on 2024-05-30
185 Increasing Signal Intensity of Fluorescent Oligo-Labeled Antibodies to Enable Combination Multiplexing
McCarthy, M. E.; Lu, X.; Ogunleye, O.; Latham, D. R.; Abravanel, M.; Pritko, D.; Huggins, J. R.; Haskell, C. V.; Patel, N. D.; Pittman, Z. A.; Sanabria, H.; Birtwistle, M. R.
10.1101/2023.07.06.547965 — molecular biology — Posted on 2024-05-30
187 Distinct ventral tegmental area neuronal ensembles are indispensable for reward-driven approach and stress-driven avoidance behaviors
Koutlas, I.; Patrikiou, L.; van der Starre, S.; Danko, D.; Wolterink-Donselaar, I.; Luijendijk, M.; Adan, R.; Meye, F. J.
10.1101/2024.05.30.596611 — neuroscience — Posted on 2024-05-30
189 Cortical determinants of loudness perception and auditory hypersensitivity
Clayton, K. K.; McGill, M.; Awwad, B.; Stecyk, K. S.; Kremer, C.; Skerleva, D.; Narayanan, D. P.; Zhu, J.; Hancock, K. E.; Kujawa, S. G.; Kozin, E. D.; Polley, D. B.
10.1101/2024.05.30.596691 — neuroscience — Posted on 2024-05-30
190 Disrupted Hippocampal Theta-Gamma Coupling and Spike-Field Coherence Following Experimental Traumatic Brain Injury
Adam, C. D.; Mirzakhalili, E.; Gagnon, K. G.; Cottone, C.; Arena, J. D.; Ulyanova, A. V.; Johnson, V. E.; Wolf, J. A.
10.1101/2024.05.30.596704 — neuroscience — Posted on 2024-05-30
195 Flawed machine-learning confounds coding sequence annotation
Champion, D.; Chen, T.-H.; Thomson, S.; Black, M. A.; Gardner, P. P.
10.1101/2024.05.16.594598 — bioinformatics — Posted on 2024-05-30
196 Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells
Bajohr, J.; Scott, E. Y.; Olfat, A.; Sadria, M.; Lee, K.; Fahim, M.; Taha, H. T.; Lozano Casasbuenas, D.; Derham, A.; Yuzwa, S.; Bader, G. D.; Faiz, M.
10.1101/2024.05.28.596294 — developmental biology — Posted on 2024-05-30
197 Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm
Ee, L.-s.; Medina-Cano, D.; Uyehara, C.; Schwarz, C.; Goetzler, E.; Salataj, E.; Polyzos, A.; Madhuranath, S.; Evans, T.; Hadjantonakis, K.; Apostolou, E.; Vierbuchen, T.; Stadtfeld, M.
10.1101/2024.05.30.596630 — developmental biology — Posted on 2024-05-30
201 Control of lumen geometry and topology by cell proliferation rate and pressure
Lee, B. H.; Fuji, K.; Petzold, H.; Seymour, P. A.; Yennek, S.; Schewin, C.; Lewis, A.; Riveline, D.; Hiraiwa, T.; Sano, M.; Grapin-Botton, A.
10.1101/2024.05.29.596462 — developmental biology — Posted on 2024-05-30
202 Spatiotemporally resolved transcriptome atlas of developing mouse placenta reveals mechanisms of embryonic lethality.
Fu, Y.; Zeng, X.; Liu, Y.; Jia, S.; Jiang, Y.; Tan, J.; Yuan, Y.; Xia, T.; Mei, Y.; Wen, S.; Liu, X.; You, Y.; Pei, W.; Yang, C.; Shao, S.; Cheng, S.; Tian, L.; Liu, L.; Wei, X.; Liu, X.
10.1101/2024.05.28.596242 — developmental biology — Posted on 2024-05-30
203 Measures of Implicit and Explicit Adaptation Do Not Linearly Add
't Hart, B. M.; Taqvi, U.; Gastrock, R. Q.; Ruttle, J. E.; Modchalingam, S.; Henriques, D. Y. P.
10.1101/2022.06.07.495044 — neuroscience — Posted on 2024-05-30
204 Unveiling Stimulus Transduction Artifacts in Auditory Steady-State Response Experiments: Characterization, Risks, and Mitigation Strategies
Strobl, J.; Viktorin, V.; Piorecky, M.; Griskova-Bulanova, I.; Hubeny, J.; Brunovsky, M.; Palenicek, T.; Koudelka, V.
10.1101/2024.05.30.596610 — neuroscience — Posted on 2024-05-30
207 Evolution of a Plasmid Regulatory Circuit Ameliorates Plasmid Fitness Cost
Elg, C. A.; Mack, E.; Rolfsmeier, M.; McLean, T. C.; Kosterlitz, O.; Soderling, E.; Narum, S.; Rowley, P. A.; Thomas, C. M.; Top, E. M.
10.1101/2024.02.05.579024 — microbiology — Posted on 2024-05-30
208 Mucus physically restricts influenza A viral particle access to the epithelium
Kaler, L.; Engle, E. M.; Iverson, E.; Boboltz, A.; Ignacio, M. A.; Rife, M.; Scull, M. A.; Duncan, G.
10.1101/2023.08.14.553271 — microbiology — Posted on 2024-05-30
210 Early-life stress induces persistent astrocyte dysfunction resulting in fear generalisation
Guayasamin, M.; Depaauw-Holt, L. R.; Adedipe, I. I.; Ghenissa, O.; Vaugeois, J.; Duquenne, M.; Rogers, B.; Latraverse-Arquilla, J.; Peyrard, S.; Bosson, A.; Murphy-Royal, C.
10.1101/2022.12.11.519598 — neuroscience — Posted on 2024-05-30
212 N-Methyl-D-aspartate receptor hypofunction causes recurrent and transient failures of perceptual inference
Weilnhammer, V.; Rothkirch, M.; Yilmaz, D.; Fritsch, M.; Ptasczynski, L. E.; Reichenbach, K.; Roediger, L.; Corlett, P.; Sterzer, P.
10.1101/2024.05.24.595590 — neuroscience — Posted on 2024-05-30
214 Whole-Brain Causal Discovery Using fMRI
Arab, F.; Ghassami, A.; Jamalabadai, H.; Peters, M. A. K.; Nozari, E.
10.1101/2023.08.12.553067 — neuroscience — Posted on 2024-05-30
216 KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation
Anastas, V.; Chavdoula, E.; La Ferlita, A.; Soysal, B.; Cosentini, I.; Nigita, G.; Kearse, M. G.; Tsichlis, P. N.
10.1101/2024.05.22.595403 — cancer biology — Posted on 2024-05-30
219 Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis
Maio, M.; Barros, J.; Joly, M.; Vahlas, Z.; Marin Franco, J. L.; Genoula, M.; Monard, S.; Vecchione, M. B.; Fuentes, F.; Gonzalez Polo, V.; Quiroga, M. F.; Vermeulen, M.; Vu Manh, T. P.; Argüello, R. J.; Inwentarz, S.; Musella, R.; Ciallella, L.; Gonzalez Montaner, P.; Palmero, D.; Lugo Villarino, G.; Sasiain, M. d. C.; Neyrolles, O.; Verollet, C.; Balboa, L.
10.1101/2023.04.03.535400 — immunology — Posted on 2024-05-30
220 Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in a F2 Cross of Selectively-Bred Rats
Hebda-Bauer, E. K.; Hagenauer, M. H.; Munro, D. B.; Blandino, P.; Meng, F.; Arakawa, K.; Chitre, A. S.; Ozel, A. B.; Mohammadi, P.; Watson, S. J.; Flagel, S. B.; Li, J.; Palmer, A. A.; Akil, H.
10.1101/2022.07.14.500129 — neuroscience — Posted on 2024-05-30
221 scRNA-seq reveals transcriptional dynamics of Encephalitozoon intestinalis parasites in human macrophages
Jaroenlak, P.; McCarty, K. L.; Xia, B.; Lam, C.; Zwack, E. E.; Yanai, I.; Bhabha, G.; Ekiert, D. C.
10.1101/2024.05.30.596468 — microbiology — Posted on 2024-05-30
225 Patient-specific multi-physics simulations of fibrotic changes in left atrial tissue mechanics impact on hemodynamics
Gonzalo, A.; Augustin, C.; Bifulco, S. F.; Telle, A.; Chahine, Y.; Kassar, A.; Guerrero-Hurtado, M.; Duran, E.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; Plank, G.; Akoum, N.; Boyle, P. M.; del Alamo, J. C.
10.1101/2024.05.29.596526 — bioengineering — Posted on 2024-05-30
229 Activation of Heme Metabolism Promotes Tissue Health after Intraarticular Injury or Surgical Exposure
Liman, S.; Gomez-Contreras, P. C.; Hines, M. R.; Fisher, J. S.; Lu, K. J.; McNally, L. D.; Sakyi, M. Y.; Wagner, B. A.; Goetz, J. E.; Byrne, J. D.; Coleman, M. C.
10.1101/2024.05.29.596521 — cell biology — Posted on 2024-05-30
231 Structural and Biophysical Dynamics of Fungal Plasma Membrane Proteins and Implications for Echinocandin Action in Candida glabrata
Jiang, J.; Keniya, M. V.; Puri, A.; Zhan, X.; Cheng, J.; Wang, H.; Lin, G.; Lee, Y.-K.; Jaber, N.; Hassoun, Y.; Shor, E.; Shi, Z.; Lee, S.-H.; Xu, M.; Perlin, D. S.; Dai, W.
10.1101/2024.05.29.596243 — cell biology — Posted on 2024-05-30
232 HIF1α controls adipose tissue growth through metabolic rechanneling
Zhu, C.; Wu, M.; Pham, M. D.; Wang, Y.; Das, A. P.; Mao, Y.; Mirtschink, P.; Yuan, T.; Krishnan, J.
10.1101/2024.05.28.596336 — cell biology — Posted on 2024-05-30
235 CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation
Kong, W.; Hara, M.; Tokunaga, Y.; Okumura, K.; Hirano, Y.; Miao, J.; Takenoshita, Y.; Hashimoto, M.; Sasaki, H.; Fujimori, T.; Wakabayashi, Y.; Fukagawa, T.
10.1101/2024.05.29.596395 — cell biology — Posted on 2024-05-30
236 Transcriptomic signatures and network-based methods uncover new Senescent Cell Anti-Apoptotic Pathways and Senolytics
Olascoaga, S.; Konigsberg, M.; Espinal-Enriquez, J.; Tovar, H.; Matadamas-Martinez, F.; Perez-Villanueva, J.; Lopez-Diazguerrero, N. E.
10.1101/2024.05.28.596326 — cell biology — Posted on 2024-05-30
237 Maintenance of haematopoietic stem cells by JAK inhibition and increased tyrosine-unphosphorylated STAT5
williams, m. J.; Wang, X.; Grondys-Katarba, G.; Bastos, H. P.; Wantoch, M.; Park, J.; Johnson, C.; Mende, N.; Mantica, G.; Calderbank, E.; Hannah, R.; Wu, Q.; Jin, S.; Asby, R.; Kinston, S.; Wilson, N.; Hamilton, T.; Pask, D.; Sneade, R.; Vassiliou, G.; Campbell, P.; Baxter, J. E.; Laurenti, E.; Li, J.; Gottgens, B.; Green, A. R.
10.1101/2024.05.29.596460 — cell biology — Posted on 2024-05-30
238 MYBPC3 D389V Variant Induces Hypercontractility in Cardiac Organoids
Desai, D.; Song, T.; Singh, R.; Baby, A.; McNamara, J.; Green, L.; Nabavizadeh, P.; Ericksen, M.; Bazrafshan, S.; Natesan, S.; Sadayappan, S.
10.1101/2024.05.29.596463 — cell biology — Posted on 2024-05-30
239 MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migration
Xu, P.; Zhang, R.; Zhou, Z.; Xu, H.; Li, Y.; Yang, M.; Lin, R.; Wang, Y.; Huang, X.; Xie, Q.; Meng, W.
10.1101/2024.05.28.596185 — cell biology — Posted on 2024-05-30
242 Dual Mechanism of Action: Exosomes from Human iPSC-Cardiomyocytes and Mesenchymal Stem Cells Restore Injured Myocardium
Tzng, E.; Bayardo, N. A.; Ikeda, G.; Takashima, H.; Lyons, J.; Bennett, M.; O'Brien, C. G.; Yang, P. C.
10.1101/2024.05.29.596548 — cell biology — Posted on 2024-05-30
243 The epithelial adherens junction component PLEKHA7 regulates ECM remodeling and cell behavior through miRNA-mediated regulation of MMP1 and LOX
Daulagala, A. C.; Cetin, M.; Nair-Menon, J.; Jimenez, D. W.; Bridges, M. C.; Bradshaw, A. D.; Sahin, O.; Kourtidis, A.
10.1101/2024.05.28.596237 — cell biology — Posted on 2024-05-30
244 APOE Impacts Lipid Trafficking in Retinal Pigment Epithelium Cells
Richards, S. E.; Demirs, J.; Jose, S.; Fan, L.; Xu, Y.; Esterberg, R.; Huang, C.-L.; Wilson, C. W.; Saint-Geniez, M.; Liao, S.-M.
10.1101/2024.05.30.596647 — cell biology — Posted on 2024-05-30
245 Protamine 2 Deficiency Results In Septin 12 Abnormalities
Sanovec, O.; Frolikova, M.; Kraus, V.; Vondrakova, J.; Qasemi, M.; Spevakova, D.; Simonik, O.; Moritz, L.; Caswell, D. L.; Liska, F.; Ded, L.; Cerny, J.; Avidor-Reiss, T.; Hammoud, S.; Schorle, H.; Postlerova, P.; Steger, K.; Komrskova, K.
10.1101/2024.05.28.596175 — cell biology — Posted on 2024-05-30
246 Quantitative imaging of loop extruders rebuilding interphase genome architecture after mitosis
Brunner, A.; Morero, N. R.; Zhang, W.; Hossain, M. J.; Lampe, M.; Pflaumer, H.; Halavatyi, A.; Peters, J.-M.; Beckwith, K. S.; Ellenberg, J.
10.1101/2024.05.29.596439 — cell biology — Posted on 2024-05-30
248 Critical role of Gα12 and Gα13 proteins in TGF-β-induced myofibroblast differentiation.
Reed, E. B.; Sitikov, A.; Hamanaka, R. B.; Cetin-Atalay, R.; Mutlu, G. M.; Mongin, A. A.; Dulin, N. O.
10.1101/2024.05.29.596473 — cell biology — Posted on 2024-05-30
250 Cell-specific nanoengineering strategy disrupts tolerogenic signaling from myeloid-derived suppressor cells to invigorate antitumor immunity in pancreatic cancer
Deshpande, N. U.; Bianchi, A.; Amirian, H.; De Castro Silva, I.; Rafie, C. I.; Surnar, B.; Rajkumar, K.; Ogobuiro, I.; Patel, M.; Mehra, S.; Nagathihalli, N.; Merchant, N. B.; Dhar, S.; Datta, J.
10.1101/2024.05.25.594901 — cancer biology — Posted on 2024-05-30
251 In Vivo Simvastatin and Brain Radiation in a Model of HER2+ Inflammatory Breast Cancer Brain Metastasis
Kumar, S.; Larson, R. A.; Stecklein, S.; Reddy, J.; Debeb, B. G.; Amos, R. A.; Cologna, S. M.; Woodward, W. A.
10.1101/2024.05.25.595905 — cancer biology — Posted on 2024-05-30
253 Association between mosaic loss of chromosome Y and pulmonary fibrosis susceptibility and severity
Wang, D.; Hadad, N.; Moss, S.; Lopez-Jimenez, E.; Johnson, S. R.; Maher, T. M.; Molyneaux, P. L.; Zhao, Y.; Perry, J. R. B.; Wolters, P. J.; Kropski, J. A.; Jenkins, R. G.; Banovich, N. E.; Stewart, I.
10.1101/2024.05.25.595885 — genomics — Posted on 2024-05-30
254 Whole-Genome Sequencing of a Janthinobacterium sp. Isolated from the Patagonian Desert
Cavanaugh, N. T.; Kumar, G.; Reverdy Pearson, A.; Colbert, J.; Riquelme, C.; Hudson, A. O.; Chai, Y.; Godoy, V.
10.1101/2024.02.11.579814 — genomics — Posted on 2024-05-30
255 Whole-Genome Sequencing of Three Extremophile Bacillus sp. Strains Isolated from the Atacama Desert
Cavanaugh, N. T.; Kumar, G.; Couto Frignani, M.; Thewedros, N.; Twahirwa, M.; Riquelme, C.; Hudson, A.; Chai, Y.; Godoy, V.
10.1101/2024.02.11.578748 — genomics — Posted on 2024-05-30
260 Protective effect of P2Y receptors antagonism on stress-induced retinal degeneration
Bao, Y.; Bond, K.; Sarraf, P.; Esterberg, R.; Serpa, M.; Twarog, M.; Xu, Y.; MacLeod, H.; Huang, Q.; Saint-Geniez, M.
10.1101/2024.05.28.596247 — cell biology — Posted on 2024-05-30
261 The Latent Aging of Cells
Niimi, P.; Gould, V.; Thrush-Evensen, K.; Levine, M. E.
10.1101/2024.05.28.596284 — cell biology — Posted on 2024-05-30
262 FICD deficiency protects mice from hypertrophy-induced heart failure via BiP-mediated activation of the UPRER and ER-phagy
Lacy, S. M.; Taubitz, R. J.; Urban, N. D.; Turowski, S. N.; Smith, E. D.; Helms, A. S.; Michele, D. E.; Truttmann, M. C.
10.1101/2024.05.28.596287 — cell biology — Posted on 2024-05-30
263 Identification of potential inflammation markers for outgrowth of cow's milk allergy
Hendrickx, D. M.; Long, M.; PRESTO study team, ; Wopereis, H.; van der Molen, R. G.; Belzer, C.
10.1101/2024.05.24.595813 — immunology — Posted on 2024-05-30
268 Artemisinin resistance mutations in Pfcoronin impede hemoglobin uptake
Ullah, I.; Farringer, M. A.; Burkhard, A. Y.; Hathaway, E.; Khushu, M.; Willett, B. C.; Shin, S. H.; Sharma, A. I.; Martin, M. C.; Shao, K. L.; Dvorin, J. D.; Hartl, D. L.; Volkman, S. K.; Bopp, S.; Absalon, S.; Wirth, D. F.
10.1101/2023.12.22.572193 — cell biology — Posted on 2024-05-30
270 A distributed brain response predicting the facial expression of acute nociceptive pain
Picard, M.-E.; Kunz, M.; Chen, J.-I.; Coll, M.-P.; Vachon-Presseau, E.; Wager, T.; Rainville, P.
10.1101/2023.07.26.550504 — neuroscience — Posted on 2024-05-30
274 Residence-colonization trade-off and niche differentiation enable the coexistence of Escherichia coli phylogroups in healthy humans
Morel-Journel, T.; Lehtinen, S.; Cotto, O.; Amia, R.; Clermont, O.; Dion, S.; Figueroa, C.; Martinson, J.; Ralaimazava, P.; Duval, X.; Nowrouzian, F. L.; Walk, S.; Denamur, E.; Blanquart, F.
10.1101/2023.08.10.552787 — evolutionary biology — Posted on 2024-05-30
276 Limited potexvirus diversity in eastern Gulf of Mexico seagrass meadows
Lim, S. J.; Rosario, K.; Kernbach, M. E.; Gross, A. J.; Furman, B. T.; Breitbart, M.
10.1101/2023.12.11.571111 — microbiology — Posted on 2024-05-30
277 Robust Optogenetic Inhibition with Red-light-sensitive Anion-conducting Channelrhodopsins
Oppermann, J.; Rozenberg, A.; Fabrin, T.; Gonzalez-Cabrera, C.; Parker, R. E. S.; Beja, O.; Prigge, M.; Hegemann, P.
10.1101/2023.06.09.544329 — biophysics — Posted on 2024-05-30
280 Spatial Patterning Analysis of Cellular Ensembles (SPACE) discovers complex spatial organization at the cell and tissue levels
Schrom, E. C.; McCaffrey, E. F.; Sreejithkumar, V.; Radtke, A. J.; Ichise, H.; Arroyo-Mejias, A.; Speranza, E.; Arakkal, L.; Thakur, N.; Grant, S.; Germain, R. N.
10.1101/2023.12.08.570837 — bioinformatics — Posted on 2024-05-30
281 Delineating redox cooperativity in water-soluble and membrane multiheme cytochromes through protein design
Hardy, B. J.; Dubiel, P.; Bungay, E. L.; Rudin, M.; Williams, C.; Arthur, C. J.; Guberman-Pfeffer, M. J.; Oliveira, A. S. F.; Curnow, P.; Anderson, J. L. R.
10.1101/2024.03.21.586059 — biochemistry — Posted on 2024-05-30
288 Suppression of autophagy induces senescence in the heart
Zhai, P.; Sung, E.-A.; Shiheido-Watanabe, Y.; Takayama, K.; Tian, Y.; Sadoshima, J.
10.1101/2024.05.26.595978 — cell biology — Posted on 2024-05-30
293 In vivo tracking of ex vivo generated 89Zr-oxine labeled plasma cells by PET in a non-human primate model
Young, D. J.; Edwards, A. J.; Quiroz Caceda, K. G.; Liberzon, E.; Barrientos, J.; Hong, S.; Turner, J.; Choyke, P. L.; Arlauckas, S.; Lazorchak, A.; Morgan, R. A.; Sato, N.; Dunbar, C. E.
10.1101/2024.05.24.595782 — bioengineering — Posted on 2024-05-30
297 The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to osteo-chondrogenic state
Salido, E.; de Medeiros Vieira, C.; Verdezoto Mosquera, J.; Zade, R.; Miller, C. L.; Lo Sardo, V.
10.1101/2024.05.25.595888 — cell biology — Posted on 2024-05-30
299 Bioenergetics of human spermatozoa in patients with testicular germ cell tumour
Simonik, O.; Bryndova, B.; Sur, V. P.; Ded, L.; Cockova, Z.; Benda, A.; Qasemi, M.; Pecina, P.; Pecinova, A.; Zpevakova, D.; Hradec, T.; Skrobanek, P.; Ezrova, Z.; Kratka, Z.; Kren, R.; Jeseta, M.; Boublikova, L.; Zamecnik, L.; Buchler, T.; Neuzil, J.; Postlerova, P.; Komrskova, K.
10.1101/2024.05.24.595824 — cell biology — Posted on 2024-05-30
301 Data-modeling the interplay between single cell shape, single cell protein expression, and tissue state
Tamir, Y.; Bussi, Y.; Owczare, C.; Luque, L.; Torrisi, G.; Rose, L. A.; Kliper-Gross, O.; Sander, C.; Schumacher, L.; Parsons, M.; Keren, L.; Zaritsky, A.
10.1101/2024.05.29.595857 — cell biology — Posted on 2024-05-30
302 JUNB O-GlcNAcylation-mediated promoter accessibility of metabolic genes modulates distinct epithelial lineage in pulmonary fibrosis
Thomas, M. J.; Bammert, M.-T.; Ansari, M.; Haag, L.; Ahmad, Z.; Schroeder, V.; Birch, J.; Santacruz, D.; Rust, W.; Viollet, C.; Strobel, B.; Dick, A.; Gantner, F.; Schleuter, H.; Ramirez, F.; Lize, M.; Le, H. Q.
10.1101/2024.05.27.594700 — cell biology — Posted on 2024-05-30
303 Multiwell-based G0-PCC assay for radiation biodosimetry
Royba, E.; Shuryak, I.; Ponnaiya, B.; Repin, M.; Pampou, S.; Karan, C.; Turner, H.; Garty, G.; Brenner, D. J.
10.1101/2024.05.27.596074 — cell biology — Posted on 2024-05-30
304 Branched chain α-ketoacids aerobically activate HIF1α signaling in vascular cells
Loscalzo, J.; Xiao, W.; Shrimali, N.; Oldham, W. M.; Clish, C. B.; He, H.; Wong, S. J.; Wertheim, B. M.; Arons, E.; Haigis, M. C.; Leopold, J. A.
10.1101/2024.05.29.595538 — cell biology — Posted on 2024-05-30
305 Distinct mechanisms of non-autonomous UPRER mediated by GABAergic, glutamatergic, and octopaminergic neurons.
Coakley, A. J.; Hruby, A.; Wang, J.; Bong, A.; Nair, T.; Ramos, C. M.; Alcala, A.; Averbukh, M.; Dutta, N.; Moaddeli, D.; Hicks, D.; de los Rios Rogers, M.; Sahay, A.; Curran, S. P.; Mullen, P. J.; Benayoun, B. A.; Garcia, G.; Higuchi-Sanabria, R.
10.1101/2024.05.27.595950 — cell biology — Posted on 2024-05-30
307 Temporal dynamics and metagenomics of phosphorothioate epigenomes in the human gut microbiome
Byrne, S.; DeMott, M.; Yuan, Y.; Ghanegolmohammadi, F.; Kaiser, S.; Fox, J. G.; Alm, E. J.; Dedon, P.
10.1101/2024.05.29.596306 — microbiology — Posted on 2024-05-30
308 Predicting Primary Graft Dysfunction in Lung Transplantation: Machine Learning-Guided Biomarker Discovery
Nord, D.; Brunson, J. C.; Langerude, L.; Moussa, H.; Gill, B.; Machuca, T.; Rackauskas, M.; Sharma, A. K.; Lin, C.; Emtiazjoo, A.; Atkinson, C.
10.1101/2024.05.24.595368 — immunology — Posted on 2024-05-30
309 In vivo magnetic recording of single-neuron action potentials
Klein, F. J.; Jendritza, P.; Chopin, C.; Parto-Dezfouli, M.; Solignac, A.; Fermon, C.; Pannetier-Lecoeur, M.; Fries, P.
10.1101/2023.06.30.547194 — neuroscience — Posted on 2024-05-30
310 Conservation of molecular responses upon viral infection in the non-vascular plant Marchantia polymorpha
Moner-Ross, E.; Jimenez-Gongora, T.; Villar-Martin, L.; Vogrinec, L.; Gonzalez-Miguel, V. M.; kutnjak, D.; Rubio-Somoza, I.
10.1101/2023.11.06.565823 — plant biology — Posted on 2024-05-30
311 WITHDRAWN: Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure
Lang, D.; Ni, H.; Medvedev, R.; Liu, F. V.; Alvarez-Baron, C.; Tyan, L.; Turner, D.; Warden, A.; Morotti, S.; Schrauth, T.; Rickert, C.; Proenza, C.; Chanda, B.; Kamp, T. J.; Robertson, G.; Grandi, E.; Glukhov, A. V.
10.1101/2024.04.14.589457 — physiology — Posted on 2024-05-30
312 Mechanical compressive forces increase PI3K output signaling in breast and pancreatic cancer cells
Di-Luoffo, M.; Schmitter, C.; Barrere, E.; Therville, N.; Chaouki, M.; D'Angelo, R.; Arcucci, S.; Thibault, B.; Delarue, M.; Guillermet-Guibert, J.
10.1101/2021.10.18.464825 — cancer biology — Posted on 2024-05-30
313 Intrinsic Disorder and Salt-dependent Conformational Changes of the N-terminal Region of TFIP11 Splicing Factor
Juniku, B.; Mignon, J.; Careme, R.; Genco, A.; Obeid, A. M.; Mottet, D.; MONARI, A.; Michaux, C.
10.1101/2024.02.18.580885 — biophysics — Posted on 2024-05-30
315 Use of machine learning for quantification of retinal pigment epithelium tight junctions improves assay sensitivity
Bray, M.-A.; Gao, Y.; Twarog, M.; Xu, Y.; Buchanan, N.; Zhang, Y.; Medley, Q.; Saint-Geniez, M.; Prasanna, G.; Zhang, Q.
10.1101/2024.05.24.595580 — bioinformatics — Posted on 2024-05-30
317 mRNA psi profiling using nanopore DRS reveals cell-type-specific pseudouridylation
McCormick, C. A.; Qiu, Y.; Fanari, O.; Liu, Y.; Bloch, D.; Klink, I. N.; Meseonznik, M.; Jain, M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2024.05.08.593203 — genomics — Posted on 2024-05-30
319 Invasion and spread of the neotropical leafhopper Curtara insularis (Hemiptera: Cicadellidae) in Africa and North America and the role of high-altitude windborne migration in invasive insects
Nartey, R.; Chamorro, M. L.; Buffington, M.; Afrane, Y.; Mohammed, A.; Owusu-Asenso, C.; Akosah-Brempong, G.; Pambit Zong, C.; Hendrix, S.; Dao, A.; Yaro, A.; Diallo, M.; Sanogo, Z.; Djibril, S.; Halbert, S.; Bamou, R.; Nance, C.; Bartlett, C.; Reynolds, D.; Chapman, J.; Obiri-Danso, K.; Lehmann, T.
10.1101/2024.05.24.595796 — ecology — Posted on 2024-05-30
321 The immune profile of circulating autoreactive CD4 T cells is imprinted through tissue activation during autoimmune liver diseases
Cardon, A.; Guinebretiere, T.; Dong, C.; Gil, L.; Ado, S.; Gavlovsky, P.-j.; Braud, M.; Danger, R.; Schultheiss, C.; Domene, A.; Paul-Gilloteaux, P.; Chevalier, C.; Bernier, L.; Judor, J.-P.; Fourgeux, C.; Imbert, A.; Khaldi, M.; Bardou-Jacquet, E.; Elkrief, L.; Lannes, A.; Silvain, C.; Schnee, M.; Tanne, F.; Vavasseur, F.; Brusselle, L.; Brouard, S.; Kwok, W.; Mosnier, J.-F.; Lohse, A. W.; Poschmann, J.; Binder, M.; Gournay, J.; Conchon, S.; Milpied, P.; Renand, A.
10.1101/2024.03.26.586770 — immunology — Posted on 2024-05-30
323 Systems Neuroscience Computing in Python (SyNCoPy): A Python Package for Large-scale Analysis of Electrophysiological Data
Moenke, G.; Schaefer, T.; Parto-Dezfouli, M.; Kajal, D. S.; Fuertinger, S.; Schmiedt, J. T.; Fries, P.
10.1101/2024.04.15.589590 — neuroscience — Posted on 2024-05-30
324 BRI1-mediated removal of seed coat H3K27me3 marks is a brassinosteroid-independent process
Pankaj, R.; Lima, R. B.; Luo, G.-Y.; Ehlert, S.; Del Toro-De Leon, G.; Bente, H.; Finger, P.; Sato, H.; Figueiredo, D. D.
10.1101/2023.12.07.569203 — plant biology — Posted on 2024-05-30
325 ER-located PIN5 transporter generates potent auxin sinks driven by the IAA decarboxylation pathway
Covanova, M.; Muller, K.; Klierova, N.; Abdollahi Sisi, N.; Skupa, P.; Smetana, O.; Dobrev, P. I.; Ruzicka, K.; Petrasek, J.
10.1101/2024.01.24.576992 — plant biology — Posted on 2024-05-30
326 MS2Prop: A machine learning model that directly generates de novo predictions of drug-likeness of natural products from unannotated MS/MS spectra
Voronov, G.; Lightheart, R.; Frandsen, A.; Bargh, B.; Haynes, S. E.; Spencer, E.; Schoenhardt, K. E.; Davidson, C.; Schaum, A.; Macherla, V. R.; DeBloois, E.; Healey, D.; Kind, T.; Dorrestein, P. C.; Colluru, V.; Butler, T.; Yu, M. S.
10.1101/2022.10.09.511482 — bioinformatics — Posted on 2024-05-30
330 Targeting both GD2 and B7-H3 using bispecific antibody improves tumor selectivity for GD2-positive tumors
Rosenkrans, Z. T.; Erbe, A. K.; Clemons, N. B.; Feils, A. S.; Medina-Guevara, Y.; Jeffery, J. J.; Barnhart, T. E.; Engle, J. W.; Sondel, P. S.; Hernandez, R.
10.1101/2024.05.23.595624 — bioengineering — Posted on 2024-05-30
332 Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans
Raices, M.; Balmir, F.; Silva, N.; Li, W.; Grundy, M. K.; Hoffman, D. K.; Altendorfer, E.; Camacho, C. J.; Bernstein, K.; Colaiacovo, M. P.; Yanowitz, J.
10.1101/2024.02.23.581796 — developmental biology — Posted on 2024-05-30
334 Effects of early life adversity and adolescent basolateral amygdala inhibition on corticolimbic connectivity and anxiety behaviors
Cody, C. R.; Artur de la Villarmois, E.; Miguelez Fernandez, A.; Lardizabal, J.; McKnight, C.; Tseng, K.; Brenhouse, H. C.
10.1101/2024.03.26.586708 — neuroscience — Posted on 2024-05-30
336 INSIHGT: Accessible multimodal systems biology with quantitative molecular phenotyping in 3D
Yau, C. N.; Hung, J. T. S.; Wong, T. C. Y.; Huang, B.; Wong, B. T. Y.; Chow, N. K. N.; Tsoi, E. P. L.; Tan, Y.; Li, J. J. X.; Wing, Y. K.; Lai, H. M.
10.1101/2024.05.24.595771 — bioengineering — Posted on 2024-05-30
338 A Haplotype-resolved, Chromosome-scale Genome for Malus domestica 'WA 38'
Zhang, H.; Ko, I.; Eaker, A.; Haney, S.; Khuu, N.; Ryan, K.; Appleby, A.; Hoffmann, B.; Landis, H.; Pierro, K.; Willsea, N.; Hargarten, H.; Yocca, A.; Harkess, A.; Honaas, L.; Ficklin, S.
10.1101/2024.01.10.574953 — genomics — Posted on 2024-05-29
343 How repeats rearrange chromosomes in deer mice
Gozashti, L.; Harringmeyer, O. S.; Hoekstra, H. E.
10.1101/2024.05.29.596518 — genomics — Posted on 2024-05-29
346 Loss of SPNS1, a lysosomal transporter, in the nervous system causes dysmyelination and white matter dysplasia
Ichimura, Y.; Sugiura, Y.; Katsuragi, Y.; Sou, Y.-S.; Uemura, T.; Tamura, N.; Komatsu-Hirota, S.; Ueno, T.; Koike, M.; Waguri, S.; Komatsu, M.
10.1101/2024.05.29.596535 — cell biology — Posted on 2024-05-29
350 Murine Progeria Model Exhibits Delayed Fracture Healing with Dysregulated Local Immune Response
Duke, V. R.; Philippon, M. J.; Lind, D. R. G.; Kasler, H.; Yamaura, K.; Huard, M.; Czachor, M.; Hollenbeck, J.; Brown, J.; Garcia, A.; Fukase, N.; Marcucio, R. S.; Nelson, A.-L.; Hambright, W. S.; Snapper, D. M.; Huard, J.; Bahney, C. S.
10.1101/2024.05.29.596277 — molecular biology — Posted on 2024-05-29
355 Differential prevalence and risk factors for infection with coronaviruses in bats collected during 2020 in Yunnan Province, China
Li, R.; Tendu, A.; Kane, Y.; Omondi, V.; Ying, J.; Mao, L.; Xu, S.; Xu, R.; Chen, X.; Chen, Y.; Declere, S. D.; Bienes, K. M.; Fassatoui, M.; Hughes, A. C.; Berthet, N.; Wong, G.
10.1101/2024.05.28.596354 — microbiology — Posted on 2024-05-29
358 Scarcity of fixed carbon transfer in a model microbial phototroph-heterotroph interaction
Dupuis, S.; Lingappa, U. F.; Mayali, X.; Sindermann, E. S.; Chastain, J. L.; Weber, P. K.; Stuart, R.; Merchant, S. S.
10.1101/2024.01.26.577492 — microbiology — Posted on 2024-05-29
360 Multimodal single-cell sequencing of the human cortex reveals neuronal vulnerability and activated glial cell states in focal cortical dysplasia
Galvao, I. C.; Lemoine, M.; Messias, L. A.; Araujo, P. A. O. R. A.; Geraldis, J. C.; Yasuda, C. L.; Alvim, M. K. M.; Ghizoni, E.; Tedeschi, H.; Cendes, F.; Rogerio, F.; Lopes-Cendes, I.; Veiga, D. F. T.
10.1101/2024.05.29.596419 — neuroscience — Posted on 2024-05-29
362 Gossamer: Scaling Image Processing and Reconstruction to Whole Brains
Marrett, K.; Moradi, K.; Park, C. S.; Yan, M.; Choi, C.; Zhu, M.; Akram, M.; Nanda, S.; Xue, Q.; Mun, H.-S.; Gutierrez, A. E.; Rudd, M.; Zingg, B.; Magat, G.; Wijaya, K.; Dong, H.; Yang, X. W.; Cong, J.
10.1101/2024.04.07.588466 — neuroscience — Posted on 2024-05-29
370 Evaluating apoptotic gene efficiency for CHO culture performance using targeted integration
Catalan-Tatjer, D.; Ganesan, S. K.; Martinez-Monge, I.; Grav, L. M.; Lavado Garcia, J.; Nielsen, L. K.
10.1101/2024.05.29.596411 — synthetic biology — Posted on 2024-05-29
372 Endocannabinoid regulation of inward rectifier potassium (Kir) channels
Mayar, S.; Borbuliak, M.; Zoumpoulakis, A.; Bouceba, T.; Labonte, M. M.; Ahrari, A.; Sinniah, N.; Memarpoor-Yazdi, M.; Venien-Bryan, C.; Tieleman, D. P.; D'Avanzo, N.
10.1101/2024.05.29.596143 — biophysics — Posted on 2024-05-29
373 The role of Tyr34 in proton-coupled electron transfer of human manganese superoxide dismutase
Azadmanesh, J.; Slobodnik, K.; Struble, L. R.; Cone, E. A.; Dasgupta, M.; Lutz, W. E.; Kumar, S.; Natarajan, A.; Coates, L.; Weiss, K. L.; Myles, D.; Kroll, T.; Borgstahl, G. E.
10.1101/2024.05.29.596464 — biochemistry — Posted on 2024-05-29
374 Effects of Ca2+ on the Structure and Dynamics of PIP3 in Model Membranes Containing PC and PS
Bernstein, A. D.; Yang, Y.; Osborn Popp, T. M.; Asante Ampadu, G.; Acharya, G. R.; Nieuwkoop, A. J.
10.1101/2024.05.28.596302 — biochemistry — Posted on 2024-05-29
377 The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys> isoacceptors in the P site
Turnbull, K.; Paternoga, H.; von der Weth, E.; Egorov, A. A.; Pochopien, A. A.; Zhang, Y.; Nersisyan, L.; Margus, T.; Johansson, M. J. O.; Pelechano, V.; Wilson, D. N.; Hauryliuk, V.
10.1101/2024.05.29.596377 — molecular biology — Posted on 2024-05-29
378 AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model
Willimann, M.; Tiyaboonchai, A.; Adachi, K.; Li, B.; Waldburger, L.; Nakai, H.; Grompe, M.; Thony, B.
10.1101/2024.05.29.596409 — molecular biology — Posted on 2024-05-29
379 Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN.1 sublineages
Wang, Q.; Mellis, I. A.; Bowen, A.; Kowalski-Dobson, T.; Valdez, R.; Katsamba, P. S.; Shapiro, L.; Gordon, A.; Guo, Y.; Ho, D. D.; Liu, L.
10.1101/2024.05.29.596362 — microbiology — Posted on 2024-05-29
380 Factors shaping the assembly of lichen holobionts in a tropical lichen community
Kosecka, M.; Bourceret, A.; Perez-Lamarque, B.; Guzow-Krzeminska, B.; Kukwa, M.; Flakus, A.; Rodriguez-Flakus, P.; Selosse, M.-A.
10.1101/2024.05.29.596524 — microbiology — Posted on 2024-05-29
381 Bright New Resources for Syphilis Research: Genetically Encoded Fluorescent Tags for Treponema pallidum and Sf1Ep Cells
Grillova, L.; Romeis, E.; Lieberman, N. A. P.; Tantalo, L. C.; Xu, L.; Molini, B.; Trejos, A.; Lacey, G.; Goulding, D.; Thomson, N.; Greninger, A. L.; Giacani, L.
10.1101/2024.05.29.596454 — microbiology — Posted on 2024-05-29
382 Structural and functional analysis of the Nipah virus polymerase complex
Hu, S.; Kim, H.; Yang, P.; Yu, Z.; Ludeke, B.; Mobilia, S.; Pan, J.; Stratton, M.; Bian, Y.; Fearns, R.; Abraham, J.
10.1101/2024.05.29.596445 — microbiology — Posted on 2024-05-29
387 Impact of variants and vaccination on nasal immunity across three waves of SARS-CoV-2
Long, J. M.; Miao, V. N.; Owings, A. H.; Tang, Y.; Bromley, J. D.; Kazer, S. W.; Kimler, K.; Asare, C.; Ziegler, C. G. K.; Ibrahim, S.; Jivanjee, T.; George, M.; Navia, A. W.; Drake, R. S.; Parker, A.; Billingsley, B. C.; Dotherow, P.; Tarugu, S.; Kota, S. K.; Laird, H.; Wichman, T. G.; Davis, Y. T.; Dhaliwal, N. S.; Pride, Y.; Guo, Y.; Senitko, M.; Harvey, J.; Bates, J. T.; Diamond, G.; Garrett, M. R.; Robinson, D. A.; Frame, I. J.; Lyons, J. J.; Robinson, T. O.; Shalek, A. K.; Horwitz, B. H.; Glover, S. C.; Ordovas-Montanes, J.
10.1101/2024.05.29.596308 — immunology — Posted on 2024-05-29
388 Dissecting the ocular impact of SARS-CoV-2 variants: Analysis of eye globe and retina in animal models
da Silva, J. I. G.; Kersten, V.; Munhoz Dati, L. M.; Lins, B. B.; Tozetto-Mendoza, T. R. A. P.; Rodrigues, D. d. R. F.; Barbosa, R. J. V.; Lima, S. H.; Villas Boas, L. S.; da Silva, A. d. S.; Chaim, K. T.; Mendes-Correa, M. C.; Russo, M.; Mirotti, L.; Pinto, M. A.; Martins, R. A. P.
10.1101/2024.05.29.596469 — neuroscience — Posted on 2024-05-29
389 The effects of iron deficient and high iron diets on SARS-CoV-2 lung infection and disease
Carolin, A.; Frazer, D.; Yan, K.; Bishop, C. R.; Tang, B.; Nguyen, W.; Helman, S. L.; Horvat, J.; Larcher, T.; Rawle, D. J.; Suhrbier, A.
10.1101/2024.05.29.596393 — pathology — Posted on 2024-05-29
390 DRMY1 promotes robust morphogenesis by sustaining the translation of cytokinin signaling inhibitor proteins
Kong, S.; Zhu, M.; Scarpin, M. R.; Pan, D.; Jia, L.; Martinez, R. E.; Alamos, S.; Vadde, V. L.; Garcia, H. G.; Qian, S.-B.; Brunkard, J. O.; Roeder, A. H. K.
10.1101/2023.04.07.536060 — developmental biology — Posted on 2024-05-29
391 Symmetry in frontal but not motor and somatosensory cortical projections
Papale, A. E.; Harish, M.; Paletzki, R. F.; O'Connor, N. J.; Eastwood, B. S.; Seal, R. P.; Williamson, R. S.; Gerfen, C. R.; Hooks, B. M.
10.1101/2023.06.02.543431 — neuroscience — Posted on 2024-05-29
392 A microglia-containing cerebral organoid model to study early life immune challenges
Buonfiglioli, A.; Kübler, R.; Missall, R.; De Jong, R.; Chan, S.; Haage, V.; Wendt, S.; Lin, A. J.; Mattei, D.; Graziani, M.; Latour, B.; Gigase, F.; Nygaard, H. B.; De Jager, P. L.; De Witte, L. D.
10.1101/2024.05.24.595814 — neuroscience — Posted on 2024-05-29
397 Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life
Lazar-Contes, I.; Arzate-Mejia, R.; Tanwar, D. K.; Steg, L.; Crespo, M.; Feudjio, O.; Germain, P.-L.; Mansuy, I. M.
10.1101/2020.08.20.259374 — developmental biology — Posted on 2024-05-29
398 Defining unique structural features in the MAFA and MAFB transcription factors that control Insulin gene activity
Cha, J.; Tong, X.; Coate, K. C.; Guo, M.; Liu, J.-H.; Reynolds, G.; Walker, E. M.; Stein, R. A.; Mchaourab, H.; Stein, R.
10.1101/2023.08.23.554429 — molecular biology — Posted on 2024-05-29
402 Serum Proteome Profiling Identifies N-Cadherin and C-Met as Early Marker Candidates of Therapeutic Response to Neoadjuvant Chemotherapy in Breast Cancer
Steenbuck, I. D.; Cosenza-Contreras, M.; Froehlich, K.; Mayer, B.; Kurowski, K.; Reinold, M.; Fahrner, M.; Hause, F.; Feilen, T.; Seredynsksa, A.; Ritter, A.; Arnoux, A.; Biniossek, M. L.; Weiss, D.; Noethling, C.; Jaeger, M.; Erbes, T.; Schilling, O.
10.1101/2024.05.24.595719 — cancer biology — Posted on 2024-05-29
403 RUCova: Removal of Unwanted Covariance in mass cytometry data
Astaburuaga-Garcia, R.; Sell, T.; Mutlu, S.; Sieber, A.; Lauber, K.; Bluethgen, N.
10.1101/2024.05.24.595717 — bioinformatics — Posted on 2024-05-29
404 Maggot: An ecosystem for sharing metadata within the web of FAIR Data
Jacob, D.; Ehrenmann, F.; David, R.; Tran, J.; Mirande-Ney, C.; Chaumeil, P.
10.1101/2024.05.24.595703 — bioinformatics — Posted on 2024-05-29
405 Discovery of knock-down resistance in the major malaria vector Anopheles funestus.
Odero, J.; Dennis, T. P.; Polo, B.; Nwezeobi, J.; Bodde, M.; Nagi, S. C.; Hernandez-Koutoucheva, A.; Nambunga, I. H.; Bwanary, H.; Mkandawile, G.; Govella, N. J.; Kaindoa, E. W.; Ferguson, H. M.; Ochomo, E.; Clarkson, C. S.; Miles, A. M.; Lawniczak, M. K. N.; Weetman, D.; Baldini, F.; Okumu, F. O.
10.1101/2024.03.13.584754 — genomics — Posted on 2024-05-29
406 Identifying signals of memory from observations of animal movements
Kim, D.; Thompson, P.; Wolfson, D.; Merkle, J.; Oliveira-Santos, L. G. R.; Forester, J.; Avgar, T.; Lewis, M.; Fieberg, J.
10.1101/2023.08.15.553411 — ecology — Posted on 2024-05-29
409 Kappa Opioid Receptor Antagonism Restores Phosphorylation, Trafficking and Behavior induced by a Disease Associated Dopamine Transporter Variant
Mayer, F. P.; Stewart, A.; Varman, D. R.; Moritz, A. E.; Foster, J. D.; Owens, A. W.; Areal, L. B.; Gowrishankar, R.; Velez, M.; Wickham, K.; Phelps, H.; Katamish, R.; Rabil, M. J.; Jayanthi, L. D.; Vaughan, R. A.; Daws, L. C.; Blakely, R.; Ramamoorthy, S.
10.1101/2023.05.03.539310 — neuroscience — Posted on 2024-05-29
410 Adolescent social anxiety is associated with diminished discrimination of anticipated threat and safety in the bed nucleus of the stria terminalis
Hur, J.; Tillman, R. M.; Kim, H. C.; Didier, P.; Anderson, A. S.; Islam, S.; Stockbridge, M. D.; De Los Reyes, A.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.
10.1101/2023.10.30.564701 — neuroscience — Posted on 2024-05-29
411 Learning the Language of Antibody Hypervariability
Singh, R.; Im, C.; Qiu, Y.; Mackness, B.; Gupta, A.; Sorenson, T.; Sledzieski, S.; Erlach, L.; Wendt, M.; Nanfack, Y.; Bryson, B. D.; Berger, B.
10.1101/2023.04.26.538476 — bioinformatics — Posted on 2024-05-29
415 WITHDRAWN: Staphylococcus aureus-serine protease-like protein B (SplB) activates PAR2 and induces endothelial barrier dysfunction
Chandrabalan, A.; Thibeault, P. E.; Smiljanov, B.; Mittmann, L. A.; Deinhardt-Emmer, S.; Nordengrün, M.; Iqbal, J.; Mrochen, D. M.; Chamling, B.; Rauch, B. H.; Reichel, C. A.; Ramachandran, R.; Bröker, B. M.; Darisipudi, M. N.
10.1101/2020.12.30.424670 — immunology — Posted on 2024-05-29
418 The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.
Kyriukha, Y.; Watkins, M. B.; Redington, J. M.; Dastvan, R.; Uversky, V. N.; Hopkins, J. B.; Pozzi, N.; Korolev, S.
10.1101/2023.06.01.543259 — biophysics — Posted on 2024-05-29
421 Microbiome-Derived Prion-Like Proteins and Their Potential to Trigger Cognitive Dysfunction
Seira Curto, J.; Dominguez Martinez, A.; Sotillo Sotillo, P.; Serrat Garcia, M.; Girona del Pozo, M.; Fernandez Gallegos, M. R.; Sanchez de Groot, N.
10.1101/2023.10.19.563052 — molecular biology — Posted on 2024-05-29
422 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus
Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pigearias, R.; Tejero, G.; Lootvoet, J.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.
10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-05-29
423 Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons
Shore, A. N.; Li, K.; Safari, M.; Qunies, A. M.; Spitznagel, B. D.; Weaver, C. D.; Emmitte, K.; Frankel, W.; Weston, M. C.
10.1101/2023.10.11.561953 — neuroscience — Posted on 2024-05-29
430 mRNA Vaccine-Induced SARS-CoV-2 Spike-Specific IFN-γ and IL-2 T-cell Responses are Predictive of Serological Neutralization and are Transiently Enhanced by Pre-Existing Cross-Reactive Immunity
Samaan, P.; Korosec, C.; Budylowski, P.; Chau, S. L. L.; Pasculescu, A.; Qi, F.; Delgado-Brand, M.; Tursun, T. R.; Mailhot, G.; Dayam, R. M.; Arnold, C. R.; Langlois, M.-A.; Patel, A.; de Launay, K. Q.; Boyd, J. M.; Takaoka, A.; Colwill, K.; McGeer, A.; Straus, S.; Gingras, A.-C.; Heffernen, J. M.; Ostrowski, M.
10.1101/2024.05.28.596157 — immunology — Posted on 2024-05-29
431 Dynamics of Brain Connectivity across the Alzheimer's Disease Spectrum: a magnetoencephalography study
Carrasco-Gomez, M.; Garcia-Colomo, A.; Cabrera-Alvarez, J.; Bruna, R.; Santos, A.; Maestu, F.
10.1101/2024.03.14.584574 — neuroscience — Posted on 2024-05-29
434 Auto-loaded TRAIL-exosomes derived from induced neural stem cells for brain cancer therapy
Zhang, X.; Taylor, H.; Valdivia, A.; Dasari, R.; Buckley, A.; Bonacquisti, E.; Nguyen, J.; Kanchi, K.; Corcoran, D. L.; Herring, L. E.; Steindler, D. A.; Baldwin, A.; Hingtgen, S.; Satterlee, A. B.
10.1101/2024.05.24.595724 — cancer biology — Posted on 2024-05-29
436 Predicted mechanistic impacts of human protein missense variants
Janes, J.; Muller, M.; Selvaraj, S.; Manoel, D.; Stephenson, J.; Goncalves, C.; Lafita, A.; Polacco, B.; Obernier, K.; Alasoo, K.; Lemos, M. C.; Krogan, N.; Martin, M.; Saraiva, L. R.; Burke, D.; Beltrao, P.
10.1101/2024.05.29.596373 — bioinformatics — Posted on 2024-05-29
440 Mining the UniProtKB/Swiss-Prot database forantimicrobial peptides
Li, C.; Sutherland, D.; Salehi, A.; Richter, A.; Lin, D.; Aninta, S. I.; Ebrahimikondori, H.; Yanai, A.; Coombe, L.; Warren, R. L.; Kotkoff, M.; Hoang, L. M. N.; Helbing, C. C.; Birol, I.
10.1101/2024.05.24.595811 — bioinformatics — Posted on 2024-05-29
441 Decellularized biohybrid nerve promotes motor axon projections
Mehta, A. S.; Zhang, S. L.; Xie, X.; Khanna, S.; Tropp, J.; Ji, X.; Daso, R.; Franz, C.; Jordan, S.; Rivnay, J.
10.1101/2024.05.24.595727 — bioengineering — Posted on 2024-05-29
442 Right ventricular stiffening and anisotropy alterations in pulmonary hypertension: Mechanisms and relations to function
Neelakantan, S.; Vang, A.; Mehdi, R. R.; Nicely, P.; Imran, T.; Zhang, P.; Choudhary, G.; Avazmohammadi, R.
10.1101/2024.05.24.592212 — bioengineering — Posted on 2024-05-29
445 Ancient eukaryotic protein interactions illuminate modern genetic traits and disorders
Cox, R. M.; Papoulas, O.; Shril, S.; Lee, C.; Gardner, T.; Battenhouse, A. M.; Lee, M.; Drew, K.; McWhite, C. D.; Yang, D.; Leggere, J. C.; Durand, D.; Hildebrandt, F.; Wallingford, J. B.; Marcotte, E. M.
10.1101/2024.05.26.595818 — evolutionary biology — Posted on 2024-05-29
449 A longitudinal atlas of post-viral lung regeneration reveals persistent injury-associated cell states
Niethamer, T. K.; Planer, J. D.; Morley, M. P.; Babu, A.; Basil, M. C.; Cantu, E.; Frank, D. B.; Diamond, J. M.; Nottingham, A. N.; Li, S.; Levin, L. I.; Zhou, S.; Morrisey, E. E.
10.1101/2024.05.24.595801 — cell biology — Posted on 2024-05-29
450 Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
Garcia-Cuesta, E. M.; Martinez, P.; Selvaraju, K.; Ulltjärn, G.; Gomez Pozo, A. M.; D'Agostino, G.; Gardeta, S.; Quijada-Freire, A.; Blanco Gabella, P.; Roca, C.; del Hoyo, D.; Jimenez-Saiz, R.; Garcia-Rubia, A.; Soler Palacios, B.; Lucas, P.; Ayala-Bueno, R.; Santander Acerete, N.; carrasco, y.; Oscar Sorzano, C.; Martinez, A.; Campillo, N. E.; Jensen, L. D.; Rodriguez Frade, J. M.; Santiago, C.; Mellado, M.
10.1101/2023.11.19.567737 — cell biology — Posted on 2024-05-29
451 Whole Genome 3D Blood Biopsy Profiling of Canine Cancers: Development and Validation of EpiSwitch Multi-Choice Array-Based Diagnostic Test.
Hunter, E.; Salter, M.; Powell, R.; Dring, A.; Naithani, T.; Vugrinec, D.; Shliaiev, K.; Issa, M.; Weston, C.; Hatton, A.; Gebregzabhar, A.; Green, J.; Blum, A.; Guiel, T.; Fritz, S.; Seelig, D.; Modiano, J. F.; Akoulitchev, A.
10.1101/2024.05.22.595358 — molecular biology — Posted on 2024-05-29
452 Transcriptome Analysis Identified SPP1+ Monocytes as a Key in Extracellular Matrix Formation in Thrombi
Kitano, T.; Sasaki, T.; Matsui, T.; Kohara, M.; Ogawa, K.; Todo, K.; Nakamura, H.; Sugiura, Y.; Shimada, Y.; Okazaki, S.; Iida, J.; Shimazu, K.; Morii, E.; Sakaguchi, M.; Nishio, M.; Yokoe, M.; Kishima, H.; Mochizuki, H.
10.1101/2024.05.28.594130 — molecular biology — Posted on 2024-05-29
453 Systematic deconstruction of myeloid cell signaling in tuberculosis granulomas reveals IFN-γ, TGF-β, and time are associated with conserved myeloid diversity
Peters, J. M.; Gideon, H. P.; Hughes, T. K.; Gunnarson, C. E.; Maiello, P.; Mugahid, D.; Nyquist, S. K.; Bromley, J.; Blainey, P. C.; Junecko, B. F.; Nelson, M. L.; Lauffenburger, D. A.; Lin, P. L.; Flynn, J. L.; Shalek, A. K.; Fortune, S. M.; Mattila, J. T.; Bryson, B. D.
10.1101/2024.05.24.595747 — immunology — Posted on 2024-05-29
454 Discovery and characterization of dietary antigens in oral tolerance
Blum, J. E.; Kong, R.; Schulman, E. A.; Chen, F. M.; Upadhyay, R.; Romero-Meza, G.; Littman, D. R.; Fischbach, M.; Nagashima, K.; Sattely, E. S.
10.1101/2024.05.26.593976 — immunology — Posted on 2024-05-29
457 Deficiency of the histone lysine demethylase KDM5B causes autism-like phenotypes via increased NMDAR signalling
Perez-Sisques, L.; Bhatt, S. U.; Caruso, A.; Ahmed, M. U.; Gileadi, T. E.; Spring, S.; Hendy, E.; Taylor-Papadimitriou, J.; Cash, D.; Clifton, N.; Ellegood, J.; Andreae, L. C.; Lerch, J. P.; Scattoni, M. L.; Giese, K. P.; Fernandes, C.; Basson, M. A.
10.1101/2024.05.28.596232 — neuroscience — Posted on 2024-05-29
459 Developmental maturation of millimeter-scale functional networks across brain areas
Powell, N. J.; Hein, B.; Kong, D.; Elpelt, J.; Mulholland, H. N.; Kaschube, M.; Smith, G. B.
10.1101/2024.05.28.595371 — neuroscience — Posted on 2024-05-29
460 Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility
McCluskey, K. E.; Stovell, K. M.; Law, K.; Kostyanovskaya, E.; Schmidt, J.; Exner, C. R.; Dea, J.; Brimble, E.; State, M. W.; Willsey, A. J.; Willsey, H. R.
10.1101/2024.05.28.593642 — neuroscience — Posted on 2024-05-29
461 micronuclAI: Automated quantification of micronuclei for assessment of chromosomal instability.
Ibarra-Arellano, M. A.; Caprio, L. A.; Hada, A.; Stotzem, N.; Cai, L.; Shah, S.; Melms, J. C.; Wuennemann, F.; Izar, B.; Schapiro, D.
10.1101/2024.05.24.595722 — systems biology — Posted on 2024-05-29
462 ForSys: non-invasive stress inference from time-lapse microscopy
Borges, A.; Miranda-Rodriguez, J. R.; Ceccarelli, A.; Ventura, G.; Sedzinski, J.; Lopez-Schier, H.; Chara, O.
10.1101/2024.05.28.595800 — systems biology — Posted on 2024-05-29
464 Benchmarking of bioinformatics tools for the hybrid de novo assembly of human whole-genome sequencing data
Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Jaspez, D.; Corrales, A.; Marcelino-Rodriguez, I.; Lorenzo-Salazar, J. M.; Gonzalez-Montelongo, R.; Flores, C.
10.1101/2024.05.28.595812 — bioinformatics — Posted on 2024-05-29
465 Intra- and inter-chain contacts determine TCR specificity: applying protein co-evolution methods to TCRαβ pairing
Milighetti, M.; Nagano, Y.; Henderson, J.; Hershberg, U.; Tiffeau-Mayer, A.; Bitbol, A.-F.; Chain, B.
10.1101/2024.05.24.595718 — immunology — Posted on 2024-05-29
466 Transfer learning reveals sequence determinants of the quantitative response to transcription factor dosage
Naqvi, S.; Kim, S.; Tabatabaee, S.; Pampari, A.; Kundaje, A.; Pritchard, J. K.; Wysocka, J.
10.1101/2024.05.28.596078 — genomics — Posted on 2024-05-29
467 PITPβ promotes COPI vesicle fission through lipid transfer and membrane contact formation
Park, K.; Ju, S.; Choi, H.; Gao, P.; Bang, G.; Choi, J. H.; Jang, J.; Morris, A.; Kang, B.-H.; Hsu, V. W.; Park, S.-Y.
10.1101/2024.05.27.596058 — cell biology — Posted on 2024-05-29
470 Dual-mode action of scalable, high-quality engineered stem cell-derived SIRP alpha extracellular vesicles for treating acute liver failure
Kim, S.; Kim, Y. K.; Kim, S.; Choi, Y.-S.; Lee, I.; Joo, H.; Kim, J.; Kwon, M.; Park, S.; Jo, M. K.; Choi, Y.; D'Souza, T.; Jung, J. W.; Zakhem, E.; Lenzini, S.; Woo, J.; Choi, H.; Park, J.; Park, S.-Y.; Kim, G. B.; Nam, G.-H.; Kim, I.-S.
10.1101/2024.05.24.592430 — bioengineering — Posted on 2024-05-29
471 Immunomodulatory Role of the Stem Cell Circadian Clock in Muscle Repair
Zhu, P.; Pfrender, E.; Steffeck, A.; Reczek, C.; Zhou, Y.; Thakkar, A.; Gupta, N.; Willbanks, A.; Lieber, R.; Roy, I.; Chandel, N. S.; Peek, C. B.
10.1101/2024.05.24.595728 — developmental biology — Posted on 2024-05-28
472 Nuclear membrane protein Bqt4 maintains nuclear envelope integrity by recruiting phosphatidic acid
Hirano, Y.; Sato, T.; Miura, A.; Kubota, Y.; Shindo, T.; Fukase, K.; Fukagawa, T.; Kabayama, K.; Haraguchi, T.; Hiraoka, Y.
10.1101/2023.12.21.572941 — cell biology — Posted on 2024-05-28
473 PUPpy: a primer design pipeline for substrain-level microbial detection and absolute quantification.
Ghezzi, H.; Fan, M. Y.; Ng, K. M.; Burckhardt, J. C.; Pepin, D. M.; Lin, X.; Ziels, R. M.; Tropini, C.
10.1101/2023.12.18.572184 — microbiology — Posted on 2024-05-28
474 Pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway
McKenzie, B.; Puissegur, M.-P.; Demeersseman, L.; Rodriguez, F.; Cini, E.; Mueller, S.; Valitutti, S.
10.1101/2024.05.24.595698 — immunology — Posted on 2024-05-28
477 Morphological signatures of neurogenesis and neuronal migration in hypothalamic vasopressinergic magnocellular nuclei of the adult rat
Zhang, L.; Zetter, M. A.; Hernandez, V. S.; Krabichler, Q.; Hernandez-Perez, O. R.; Jauregui-Huerta, F.; Grinevich, V.
10.1101/2023.12.10.570983 — neuroscience — Posted on 2024-05-28
478 Regeneration in the absence of canonical neoblasts in an early branching flatworm
Gasiorowski, L.; Chai, C.; Rozanski, A.; Purandare, G.; Ficze, F.; Mizi, A.; Wang, B.; Rink, J. C.
10.1101/2024.05.24.595708 — zoology — Posted on 2024-05-28
481 KIPK and KIPK-LIKE1 suppress overbending during negative hypocotyl gravitropic growth
Xiao, Y.; Zourelidou, M.; Bassukas, A. E. L.; Weller, B.; Janacek, D. P.; Schnulz, L.; Brajkovic, S.; Simura, J.; Ljung, K.; Kuster, B.; Hammes, U. Z.; Li, J.; Schwechheimer, C.
10.1101/2024.05.24.595653 — plant biology — Posted on 2024-05-28
485 Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins via Fine-tuned Diffusion Models
Zhu, J.; Li, Z.; Zhang, B.; Zheng, Z.; Zhong, B.; Bai, J.; Wang, T.; Wei, T.; Yang, J.; Chen, H.-F.
10.1101/2024.05.05.592611 — bioinformatics — Posted on 2024-05-28
486 Hippocampal neuroinflammation causes sex-specific disruptions in action selection, food approach memories, and neuronal excitation
Ganesan, K.; Ghorbanpour, S.; Kendall, W.; Broome, S. T.; Gladding, J. M.; Dhungana, A.; Abiero, A. R.; Mahmoudi, M.; Castorina, A.; Kendig, M. D.; Becchi, S.; Valova, V.; Cole, L.; Bradfield, L. A.
10.1101/2024.05.19.594460 — animal behavior and cognition — Posted on 2024-05-28
487 North Pontic crossroads: Mobility in Ukraine from the Bronze Age to the early modern period
Saag, L.; Utevska, O.; Zadnikov, S.; Shramko, I.; Gorbenko, K.; Bandrivskyi, M.; Pavliv, D.; Bruyako, I.; Grechko, D.; Okatenko, V.; Toshev, G.; Andrukh, S.; Radziyevska, V.; Buynov, Y.; Kotenko, V.; Smyrnov, O.; Petrauskas, O.; Magomedov, B.; Didenko, S.; Heiko, A.; Reida, R.; Sapiehin, S.; Aksonov, V.; Laptiev, O.; Terskyi, S.; Skorokhod, V.; Zhyhola, V.; Sytyi, Y.; Jarve, M.; Scheib, C. L.; Anastasiadou, K.; Kelly, M.; Williams, M.; Silva, M.; Barrington, C.; Gilardet, A.; Macleod, R.; Skoglund, P.; Thomas, M. G.
10.1101/2024.05.24.595769 — genomics — Posted on 2024-05-28
488 Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development
Yue, T.; Guo, Y.; Qi, X.; Zheng, W.; Zhang, H.; Wang, B.; Zhou, B.; Zeng, X.; NA, O.; He, Y.; Su, B.
10.1101/2023.05.24.542081 — evolutionary biology — Posted on 2024-05-28
490 Functional regimes define the response of the soil microbiome to environmental change
Lee, K. K.; Liu, S.; Crocker, K.; Huggins, D. R.; Tikhonov, M.; Mani, M.; Kuehn, S.
10.1101/2024.03.15.584851 — ecology — Posted on 2024-05-28
492 Spindle architecture constrains karyotype in budding yeast
Helsen, J.; Reza, M. H.; Carvalho, R.; Sherlock, G. J.; Dey, G.
10.1101/2023.10.25.563899 — cell biology — Posted on 2024-05-28
493 Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Cozzolino, K.; Sanford, L.; Hunter, S.; Molison, K.; Erickson, B.; Jones, T.; Courvan, M. C. S.; Ajit, D.; Galbraith, M. D.; Espinosa, J. M.; Bentley, D. L.; Allen, M. A.; Dowell, R. D. A.; Taatjes, D. J.
10.1101/2023.07.05.547813 — molecular biology — Posted on 2024-05-28
496 Movement-related increases in subthalamic activity optimize locomotion
Callahan, J. W.; Morales, J. C.; Atherton, J. F.; Wang, D.; Kostic, S.; Bevan, M. D.
10.1101/2023.12.07.570617 — neuroscience — Posted on 2024-05-28
501 T cells regulate intestinal motility and shape enteric neuronal responses to intestinal microbiota.
Marques de Souza, P. R.; Keenan, C. M.; Wallace, L. E.; Habibyan, Y. B.; Davoli-Ferreira, M.; Ohland, C.; Vicentini, F.; McCoy, K. D.; Sharkey, K. A.
10.1101/2024.05.23.595563 — physiology — Posted on 2024-05-28
502 FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices
Rosenstein, A.; Sambathkumar, R.; Murareanu, B.; Dhaliwal, N.; Sun, F.; Zhao, X.; Dadvar, A.; Al-attar, R.; Chai, A.; Gulati, N.; Yin, T.; Nguyen, M.; Serra, D.; Devina, T.; Gandhi, A.; Saleh, M.; Gilbert, P. M.; Kunath, T.; Laflamme, M.; Ogawa, S.; Muffat, J.; Li, Y.; Protze, S.; Nostro, C.; Garton, M. J.
10.1101/2024.05.23.595541 — bioengineering — Posted on 2024-05-28
506 Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
Genna, V.; Portella, G.; Sala, A.; Terrazas, M.; Villegas, N.; Mateo, L.; Castellazzi, C.; Labrador, M.; Avino, A.; Hospital, A.; Grandioso, A.; Aloy, P.; Brun-Heath, I.; Gonzalez, C.; Eritja, R.; Orozco, M.
10.1101/2024.05.28.596189 — molecular biology — Posted on 2024-05-28
508 Thermal variation influences the transcriptome of the major malaria vector Anopheles stephensi.
Pathak, A. K.; Quek, S.; Sharma, R.; Shiau, J. C.; Thomas, M. B.; Hughes, G. L.; Murdock, C. C.
10.1101/2024.05.27.596085 — molecular biology — Posted on 2024-05-28
511 Erythrocyte membrane protein 3 (EMAP3) is exposed on the surface of the Plasmodium berghei infected red blood cell
Hernandez, S.; Rashpa, R.; Jonsdottir, T. K.; Paoletta, M. S.; Diaz, M. R.; Chevalley-Maurel, S.; Ishizaki, T.; Janse, C. J.; Franke-Fayard, B.; Brochet, M.; Bushell, E. S.
10.1101/2024.05.28.596273 — microbiology — Posted on 2024-05-28
513 Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold
Ghosh, U.; Tse, E.; Yang, H.; Shi, M.; Carlo, C. D.; Wang, F.; Merz, G. E.; Prusiner, S. B.; Southworth, D. R.; Condello, C.
10.1101/2024.04.02.587507 — neuroscience — Posted on 2024-05-28
518 Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition
Motos, G.; Schaub, A.; David, S. C.; Costa, L.; Terrettaz, C. C.; Kaltsonoudis, C.; Glas, I.; Klein, L.; Bluvshtein, N.; Luo, B.; Violaki, K.; Pohl, M.; Hugentobler, W.; Krieger, U. K.; Pandis, S.; Stertz, S.; Peter, T.; Kohn, T.; Nenes, A.
10.1101/2024.05.28.596202 — microbiology — Posted on 2024-05-28
519 New isolates refine the ecophysiology of the Roseobacter CHAB-I-5 lineage
Lanclos, V. C.; Feng, X.; Cheng, C.; Yang, M.; Hider, C. J.; Coelho, J. T.; Kojima, C. Y.; Barnes, S. J.; Cleveland, C.; Xie, M.; Zhao, Y.; Luo, H.; Thrash, J. C.
10.1101/2024.05.28.596239 — microbiology — Posted on 2024-05-28
520 Activity-Based Protein Profiling Identifies Klebsiella pneumoniae Serine Hydrolases with Potential Roles in Host-Pathogen Interactions
Uddin, M. J.; Randall, G.; Zhu, J.; Upadhyay, T.; van Eijk, L.; Stege, P.; Masson, F. M.; Viveen, M. C.; Bogyo, M.; Fellner, M.; de Zoete, M.; Johannessen, M.; Lentz, C. S.
10.1101/2024.05.28.596221 — microbiology — Posted on 2024-05-28
523 Role of the CTCF Binding Site in Human T-Cell Leukemia Virus-1 Pathogenesis
Joseph, A.; Cheng, X.; Harding, J.; Al-Saleem, J.; Green, P.; Veis, D.; Rauch, D. A.; Ratner, L.
10.1101/2024.05.28.596170 — microbiology — Posted on 2024-05-28
524 Detection of neutralizing antibodies against arboviruses from liver homogenates
Costa, T. A.; Arruda, M. S.; Garcia-Oliveira, G. F.; Reis, E. V. S.; Guimaraes, A. C. D. S.; Moreira, G. D.; Arias, N. E. C.; Beirao, M. d. V.; Vasilakis, N.; Hanley, K. A.; Drumond, B. P.
10.1101/2024.05.28.596289 — microbiology — Posted on 2024-05-28
525 Polyphosphate mobilization influences the ability of Cryptococcus neoformans to cause disease in a murine model of cryptococcosis
Bhalla, K.; Sanchez Leon-Hing, E.; Huang, Y.-H.; French, V.; Hu, G.; Wang, J.; Kretschmer, M.; Qu, X.; Moreira, R.; Foster, E. J.; Johnson, P.; Kronstad, J.
10.1101/2024.05.28.596173 — microbiology — Posted on 2024-05-28
526 Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity
Kan, J.; Morales, A.; Hernandez, Y.; Ternei, M. A.; Lemetre, C.; Maclntyre, L. W.; Biais, N.; Brady, S. F.
10.1101/2024.05.27.596031 — microbiology — Posted on 2024-05-28
527 The CSF transcriptome in pneumococcal meningitis reveals compartmentalised host inflammatory responses associated with mortality.
Guerra-Assuncao, J.-A.; Chakroborty, P.; Pollara, G.; Venturini, C.; Mlozowa, V. S.; Denis, B.; Nyirenda, M.; Lalloo, D. G.; Noursadeghi, M.; Heyderman, R. S.; Brown, J. S.; Wall, E. C.
10.1101/2024.05.24.592913 — immunology — Posted on 2024-05-28
530 ctQC improves biological inferences from single cell and spatial transcriptomics data
Lakshmanan, V.; Kahraman, M.; Macalinao, D. C.; Gunn, N.; Venkatesh, P. N.; Meihuan, C.; Fu, C.; Qiang, L. W.; Tan, I. B.; Prabhakar, S.
10.1101/2024.05.23.594978 — bioinformatics — Posted on 2024-05-28
532 Systems Age: A single blood methylation test to quantify aging heterogeneity across 11 physiological systems
Sehgal, R.; Markov, Y.; Qin, C.; Meer, M.; Hadley, C.; Shadyab, A. H.; Casanova, R.; Manson, J. E.; Bhatti, P.; Crimmins, E. M.; Hägg, S.; Assimes, T. L.; Whitsel, E. A.; Higgins-Chen, A. T.; Levine, M.
10.1101/2023.07.13.548904 — systems biology — Posted on 2024-05-28
534 Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets
Agoro, R.; Myslinski, J.; Marambio, Y. G.; Janosevic, D.; Jennings, K. N.; Liu, S.; Hibbard, L. M.; Fang, F.; Ni, P.; Noonan, M. L.; Solis, E.; Chu, X.; Wang, Y.; Dagher, P. C.; Liu, Y.; Wan, J.; Hato, T.; White, K.
10.1101/2024.05.24.595014 — physiology — Posted on 2024-05-28
535 Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation
Waltl, L.; Speck, K.; Wildermuth, R.; Haut, F.-L.; Permann, S.; D'Avino, D.; Cerqua, I.; Siller, A.; Schennach, H.; Rossi, A.; Magauer, T.; Koeberle, A.
10.1101/2024.05.24.595516 — pharmacology and toxicology — Posted on 2024-05-28
537 Stromal mediated DNA damage promotes high grade serous ovarian cancer initiation
Garcia, G. L.; Orellana, T.; Gorecki, G.; Frisbie, L. G.; Baruwal, R.; Goldfield, E.; Beddows, I.; MacFawn, I. P.; Britt, A. K.; Hale, M. M.; Shen, H.; Buckanovich, R.; Finkel, T.; Drapkin, R.; Soong, T. R.; Bruno, T. C.; Atiya, H. I.; Coffman, L. G.
10.1101/2024.05.23.595550 — cancer biology — Posted on 2024-05-28
538 Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Schreuder, A.; de Lint, K.; Gois, M. M.; Kampen, R. A.; San Martin Alonso, M.; Nootenboom, I.; Garzero, V.; Wolthuis, R. M. F.; Noordermeer, S. M.
10.1101/2024.05.24.595688 — cancer biology — Posted on 2024-05-28
539 Clonal spheroids capture functional and genetic heterogeneity of head and neck cancer
Pandey, J.; Malik, M. Z.; Shyanti, R. k.; Parashar, P.; kujur, P. K.; Mishra, D.; Tailor, D.; Lee, J. M.; Kataria, T.; Gupta, D.; Verma, H.; Malhotra, S. V.; Kateriya, S.; Tandon, V.; Chaturvedi, R.; Singh, R. P.
10.1101/2024.05.24.595655 — cancer biology — Posted on 2024-05-28
541 Homomorphic Encryption: An Application to Polygenic Risk Scores
Knight, E.; Li, J.; Jensen, M.; Yolou, I.; Kockan, C.; Gerstein, M.
10.1101/2024.05.26.595961 — bioinformatics — Posted on 2024-05-28
542 Deciphering cis-regulatory elements using REgulamentary
Riva, S. G.; Georgiades, E.; Herrmann, J. C.; Gur, R.; Sanders, E.; Sergeant, M.; Baxter, M.; Hughes, J. R.
10.1101/2024.05.24.595662 — bioinformatics — Posted on 2024-05-28
545 Molecular Display of the Animal Meta-Venome for Discovery of Novel Therapeutic Peptides
Hsiao, M.-H.; Miao, Y.; Liu, Z.; Schutze, K.; Limjunyawong, N.; Chien, D. C.-C.; Monteiro, W. D.; Chu, L.-S.; Morgenlander, W.; Jayaraman, S.; Jang, S.-e.; Gray, J. J.; Zhu, H.; Dong, X.; Steinegger, M.; Larman, H. B.
10.1101/2024.05.27.595990 — molecular biology — Posted on 2024-05-28
546 Developmental pyrethroid exposure in mouse leads to disrupted brain metabolism in adulthood
Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Ryan, W. G.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.
10.1101/2023.10.13.562226 — neuroscience — Posted on 2024-05-28
547 A neurometabolic signature in the frontal cortex explains individual differences in effort-based decision-making
Barakat, A.; Clairis, N.; Brochard, J.; Pessiglione, M.; Godin, J.-P.; Cuenoud, B.; Xin, L.; Sandi, C.
10.1101/2024.01.23.576854 — neuroscience — Posted on 2024-05-28
552 Demonstration of Bioplastic Production from CO2 and Formate using the Reductive Glycine Pathway in E. coli
Fedorova, D.; Ben-Nissan, R.; Milshtein, E.; Jona, G.; Dezorella, N.; Feiguelman, G.; Fedorov, R.; Gomaa, A.; Lindner, A. B.; Noor, E.; Milo, R.
10.1101/2023.12.02.569694 — synthetic biology — Posted on 2024-05-28
553 KIPK and KIPK-LIKE1 suppress overbending during negative hypocotyl gravitropic growth
Xiao, Y.; Zourelidou, M.; Bassukas, A. E. L.; Weller, B.; Janacek, D. P.; Schnulz, L.; Brajkovic, S.; Simura, J.; Kuster, B.; Schwechheimer, C.; Ljung, K.; Li, J.; Hammes, U. Z.
10.1101/2024.05.24.595653 — plant biology — Posted on 2024-05-28
554 A peptide that regulates metalation and function of the Arabidopsis ethylene receptor.
Mudge, A. M.; Mehdi, S.; Michaels, W. E.; Oroza-Puente, B.; Shen, W.; Tomlinson, C.; Wei, W.; Hoppen, C.; Uzun, B.; Roy, D.; Hetherington, F. M.; Topping, J. F.; Sadanandom, A.; Groth, G.; Robinson, N. J.; Lindsey, K.
10.1101/2023.06.15.545071 — plant biology — Posted on 2024-05-28
559 FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices
Rosenstein, A.; Sambathkumar, R.; Murareanu, B.; Dhaliwal, N.; Sun, F.; Zhao, X.; Dadvar, A.; Al-attar, R.; Chai, A.; Gulati, N.; Yin, T.; Nguyen, M.; Serra, D.; Devina, T.; Saleh, M.; Gilbert, P. M.; Kunath, T.; Laflamme, M.; Ogawa, S.; Muffat, J.; Li, Y.; Protze, S.; Nostro, C.; Garton, M. J.
10.1101/2024.05.23.595541 — bioengineering — Posted on 2024-05-28
560 Realigning representational drift in mouse visual cortex by flexible brain-machine interfaces
Zhao, S.; Shen, H.; Qin, S.; Jiang, S.; Tang, X.; Lee, M.; Zhang, X.; Lee, J.; Chen, J.; Liu, J.
10.1101/2024.05.23.595627 — bioengineering — Posted on 2024-05-28
561 Targeting both GD2 and B7-H3 using bispecific antibody improves tumor selectivity for GD2-positive tumors
Rosenkrans, Z. T.; Erbe, A. K.; Clemons, N. B.; Feils, A. S.; Medina-Guevara, Y.; Jeffery, J. J.; Barnhart, T. E.; Engle, J. W.; Sondel, P. S.; Hernandez, R.
10.1101/2024.05.23.595624 — bioengineering — Posted on 2024-05-28
564 RESOLVING BIOLOGY'S DARK MATTER: SPECIES RICHNESS, SPATIOTEMPORAL DISTRIBUTION, AND COMMUNITY COMPOSITION OF A DARK TAXON
Hartop, E.; Lee, L.; Srivathsan, A.; Jones, M.; Pena-Aguilera, P.; Ovaskainen, O.; Roslin, T.; Meier, R.
10.1101/2024.05.07.592951 — ecology — Posted on 2024-05-28
566 Antibodies against medically relevant arthropod-borne viruses in the ubiquitous African rodent Mastomys natalensis
De Kesel, W.; Vanden Broecke, B.; Borremans, B.; Fourchault, L.; Willems, E.; Ceulemans, A.; Sabuni, C.; Massawe, A.; Makundi, R. H.; Leirs, H.; Peeters, M.; Verheyen, E.; Gryseels, S.; Marien, J.; Arien, K. K.
10.1101/2024.05.23.595460 — immunology — Posted on 2024-05-28
568 The Role of Metabolism in Shaping Enzyme Structures Over 400 Million Years of Evolution
Lemke, O.; Heineike, B. M.; Viknander, S.; Cohen, N.; Steenwyk, J. L.; Spranger, L.; Li, F.; Agostini, F.; Lee, C. T.; Aulakh, S. K.; Nielsen, J.; Rokas, A.; Berman, J.; Zelezniak, A.; Gossmann, T. I.; Ralser, M.
10.1101/2024.05.27.596037 — systems biology — Posted on 2024-05-27
571 The genomic and epigenomic dynamics of hemizygous genes across crops with contrasting mating systems
Peng, Y.; Wang, Y.; Liu, Y.; Fang, X.; Cheng, L.; Long, Q.; Xu, Q.; Wang, N.; Zhang, F.; Liu, Z.; Xiao, H.; Chen, S.; Hu, W.; Huang, S.; Gaut, B.; Zhou, Y.
10.1101/2024.05.24.595664 — plant biology — Posted on 2024-05-28
572 Structure-activity relationships and crucial mechanisms of the coumarin family as germination inhibitors
Fukuda, K.; Hyakutake, S.; Oishi, T.; Yoshida, M.; Koga, M.; Egami, C.; Matsura, H.; Ito, R.; Tsukahara, K.; Noda, M.; Yoshida, T.; Ryuda, N.; Nagano, Y.; Matsutaka, K.
10.1101/2024.05.23.595645 — plant biology — Posted on 2024-05-28
574 Posteruptive Loss of Enamel Proteins Concurs with Gain in Enamel Hardness
Karaaslan, H.; Walker, A. R.; Gil-Bona, A.; Depalle, B.; Bidlack, F. B.
10.1101/2024.05.23.595034 — physiology — Posted on 2024-05-28
575 Bispecific GD2 x B7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma
Erbe, A. K.; Feils, A. S.; Hampton, A.; Rosenkrans, Z. T.; Felder, M.; Wiwczar, J.; Gerhardt, D. J.; Bercher, M.; Wenke, B.; Haertle, C.; Heck, M.; VandenHeuvel, S. N.; Frankel, E.; Nielsen, M.; Spiegelman, D.; Tsarovsky, N.; Zaborek, J.; Rakhmilevich, A. L.; Hank, J. A.; Aluicio-Sarduy, E.; Engle, J.; Davis, J. H.; Glaser, B.; Subbotin, V.; Green, R.; Hernandez, R. T.; Hammer, B.; Sondel, P. M.
10.1101/2024.05.23.595588 — cancer biology — Posted on 2024-05-28
576 Mitochondrial inner membrane remodeling as a driving force of organelle shaping
Preminger, N.; Zucker, B.; Hassdenteufel, S.; Stephan, T.; Jakobs, S.; Kozlov, M.; Schuldiner, M.
10.1101/2024.05.27.595707 — cell biology — Posted on 2024-05-28
577 Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
Marsh, N. M.; Macewen, M. J. S.; Chea, J.; Kenerson, H. L.; Kwong, A. A.; Locke, T. M.; Miralles, F. J.; Sapre, T.; Gozali, N. K.; Atilla-Gokcumen, G. E.; Ong, S.-E.; Scott, J. D.; Yeung, R. S.; Sancak, Y.
10.1101/2024.05.27.596106 — cell biology — Posted on 2024-05-28
578 Genotypic identification of polyclonal plasma cells in plasma cell dyscrasias shows an aberrant single-cell phenotype with clinical implications
Da Via, M. C.; Lazzaroni, F.; Matera, A.; Marella, A.; Maeda, A.; De Magistris, C.; Pettine, L.; Fabris, S.; Pioggia, S.; Marchetti, A.; Barbieri, M.; Lonati, S.; Cattaneo, A.; Tornese, M.; Scopetti, M.; Latifinavid, N.; Castellano, G.; Torricelli, F.; Neri, A.; Fokkema, C.; Cupedo, T.; Lionetti, M.; Passamonti, F.; Bolli, N.
10.1101/2024.05.26.595470 — cancer biology — Posted on 2024-05-27
580 Distinct Tumor-TAM Interactions in IDH-Stratified Glioma Microenvironments unveiled by Single-Cell and Spatial Transcriptomics
Motevasseli, M.; Darvishi, M.; Khoshnevisan, A.; Zeinalizadeh, M.; Saffar, H.; Bayat, S.; Najafi, A.; Abbaspour, M. J.; Mamivand, A.; Olson, S. B.; Tabrizi, M.
10.1101/2024.05.23.595505 — cancer biology — Posted on 2024-05-27
582 Natural killer cells associate with epithelial cells in the pancreatic ductal adenocarcinoma tumor microenvironment
Malchiodi, Z. X.; Suter, R. K.; Deshpande, A.; Peran, I.; Harris, B. T.; Duttargi, A.; Chien, M.-J.; Hariharan, S.; Wetherill, L.; Jablonski, S. A.; Ho, W. J.; Fertig, E. J.; Weiner, L. M.
10.1101/2024.05.23.593868 — cancer biology — Posted on 2024-05-28
583 Acvr1b loss increases formation of pancreatic precancerous lesions from acinar and ductal cells of origin
Saeki, K.; Wood, I. S.; Wang, W. C. K.; Patil, S.; Sun, Y.; Schaeffer, D. F.; Su, G. H.; Kopp, J. L.
10.1101/2023.06.08.544226 — cancer biology — Posted on 2024-05-28
584 Lineage-specific proteome remodeling of diverse lung cancer cells by targeted epigenetic inhibitors
Lin, C.; Sniezek, C. M.; Giglio, R. M.; Karki, R.; McGann, C. D.; Garcia, B. A.; McFaline-Figueroa, J. L.; Schweppe, D. K.
10.1101/2024.05.23.592075 — cancer biology — Posted on 2024-05-28
585 Comprehensive multi-site profiling of the malignant pleural mesothelioma micro-environment identifies candidate molecular determinants of histopathologic type
Severson, D. T.; Freyaldenhoven, S.; Wadowski, B.; Hughes, T.; Hung, Y. P.; Chirieac, L.; Jensen, R. V.; Richards, W. G.; Sedak, A. A.; Gustafson, C. E.; Vermilya, K.; Innocenti, S.; Korle, S.; Barlow, J. S.; Couger, M. B.; Anderson, J.; Meyervitz, J.; Wang, V.; Dao, M. N.; Shalek, A. K.; De Rienzo, A.; Bueno, R.
10.1101/2024.05.24.595690 — cancer biology — Posted on 2024-05-28
586 Effective recognition of double-stranded RNA does not require activation of cellular inflammation
Drazkowska, K.; Cieslicka, J.; Pastucha, A.; Markiewicz, L.; Goryca, K.; Kowalczyk, T.; Cysewski, D.; Bausch, A.; Sikorski, P. J.
10.1101/2024.05.24.595663 — immunology — Posted on 2024-05-28
588 BUTYRATE AMELIORATES INFLAMMATION IN COLON BIOPSY SAMPLES OF IBD PATIENTS AND EXPERIMENTAL COLITIS IN MICE INVOLVING RNA BINDING PROTEIN, AUF1-IL-27 AXIS AND ACCELERATING B1a TO B10 POLARIZATION
MASID, A.; DAS, O.; ROY, D.; DUTTA, A.; SIKDAR, S.; GHOSH, A.; BANERJEE, A.; GHOSH, U.; CHOWDHURY, S. A.; MAJUMDER, S.; YAHYA, M.; SINHA, S.; BHAUMIK, M.
10.1101/2024.05.24.595646 — immunology — Posted on 2024-05-28
589 Tumour specimen cold ischemia time impacts molecular cancer drug target discovery
von der Heyde, S.; Raman, N.; Gabelia, N.; Matias-Guiu, X.; Yoshino, T.; Tsukada, Y.; Melino, G.; Marshall, J. L.; Wellstein, A.; Juhl, H.; Landgrebe, J.
10.1101/2024.05.23.595517 — cancer biology — Posted on 2024-05-28
590 TIF1γ regulates stability of T regulatory cells during inflammation
Contreras-Castillo, E.; Zambrano-Romero, J. D.; Perez-Vazquez, D.; Garcia-Patino, M. G.; Tapia-Urzua, G.; Candelario-Martinez, A.; Ramos-Balderas, J. L.; Licona-Limon, I. I.; Madera-Salcedo, I. K.; Rosetti-Scuitto, F.; Crispin-Acuna, J. C.; Noriega-Lopez, L.; Nava, P.; Recillas-Targa, F.; Kaartinen, V.; Henao-Mejia, J.; Flavell, R.; Limon, P. L.
10.1101/2024.05.23.595623 — immunology — Posted on 2024-05-28
592 Obtaining high-resolution cryo-EM structures using a common LaB6, 120-keV electron microscope equipped with a sub 200-keV optimised direct electron detector.
Venugopal, H.; Mobbs, J.; Taveneau, C.; Fox, D. R.; Vuckovic, Z.; Knott, G.; Grinter, R.; Thal, D. M.; Mick, S.; Czarnik, C.; Ramm, G.
10.1101/2024.05.26.595910 — biophysics — Posted on 2024-05-27
593 Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple AD ligands
Greven, J. A.; Wydra, J. R.; Greer, R.; Camitta, C.; Song, Y.; Brett, T. J.; Alexander-Brett, J.
10.1101/2024.05.23.595592 — biophysics — Posted on 2024-05-27
595 RNA adapts its flexibility to efficiently fold and resist unfolding
Jang, S. S.; Ray, K. K.; Lynall, D. G.; Shepard, K. L.; Nuckolls, C.; Gonzalez, R. L.
10.1101/2024.05.27.595525 — biophysics — Posted on 2024-05-27
600 Identification of 17 novel epigenetic biomarkers associated with anxiety disorders using differential methylation analysis followed by machine learning-based validation
Kwon, Y.; Blazyte, A.; Jeon, Y.; Kim, Y. J.; An, K.; Jeon, S.; Ryu, H.; Shin, D.-H.; Ahn, J.; Um, H.; Kang, Y.; Bak, H.; Kim, B.; Lee, S.; Jung, H.-T.; Shin, E.-S.; Bhak, J.
10.1101/2024.05.23.595430 — bioinformatics — Posted on 2024-05-27
601 Novel enzyme-based reduced representation method for DNA methylation profiling with low inputs
Liu, Q.; Helmin, K. A.; Dortzbach, Z. D.; Reyes Flores, C. P.; Torres Acosta, M. A.; Gurkan, J. K.; Joudi, A. M.; Mambetsariev, N.; Morales-Nebreda, L.; Perez-Leonor, X. G.; Abdala-Valencia, H.; Singer, B. D.
10.1101/2024.05.24.595803 — genomics — Posted on 2024-05-27
604 Multicellular, IVT-derived, unmodified human transcriptome for nanopore direct RNA analysis
McCormick, C. A.; Akeson, S.; Tavakoli, S.; Bloch, D.; Klink, I. N.; Jain, M.; Rouhanifard, S. H.
10.1101/2023.04.06.535889 — genomics — Posted on 2024-05-28
605 Fast and exact gap-affine partial order alignment with POASTA
van Dijk, L. R.; Manson, A. L.; Earl, A. M.; Garimella, K. V.; Abeel, T.
10.1101/2024.05.23.595521 — bioinformatics — Posted on 2024-05-27
606 Gene regulatory activity associated with PCOS revealed DENND1A-dependent testosterone production
Sankaranarayanan, L.; Brewer, K. J.; Johnson, G. D.; Barrera, A.; Venukuttan, R.; Sisk, R.; Dunaif, A.; Reddy, T. E.
10.1101/2024.05.23.595551 — genomics — Posted on 2024-05-28
612 Adaptive loss of shortwave cone opsins during genomic evolution in cartilaginous fish
Zhang, B.; Feng, Y.; Lv, M.; Jia, L.; Liao, Y.; Xu, X.; Meyer, A.; Sun, J.; Li, Y.; Zhang, Y.; Zhao, N.; Li, Y.; Bao, B.
10.1101/2024.05.27.594570 — bioinformatics — Posted on 2024-05-28
614 Proteogenomics analysis of human tissues using pangenomes
Wang, D.; Bouwmeester, R.; Zheng, P.; Dai, C.; Puente, A. S.; Shu, K.; Bai, M.; Umer, H. M.; Perez-Riverol, Y.
10.1101/2024.05.24.595489 — bioinformatics — Posted on 2024-05-28
616 RUCova: Removal of Unwanted Covariance in mass cytometry data
Astaburuaga-Garcia, R.; Sell, T.; Mutlu, S.; Sieber, A.; Lauber, K.; Bluethgen, N.
10.1101/2024.05.24.595717 — bioinformatics — Posted on 2024-05-28
617 SaprotHub: Making Protein Modeling Accessible to All Biologists
Su, J.; Li, Z.; Han, C.; Zhou, Y.; Shan, J.; Zhou, X.; Ma, D.; OPMC, T.; Ovchinnikov, S.; Yuan, F.
10.1101/2024.05.24.595648 — bioinformatics — Posted on 2024-05-28
619 AptaGPT: Advancing aptamer design with a generative pre-trained language model
Ding, S.; Yang, X.; Chan, C. H.; Ma, Y.; Yu, S.; Wang, L.; Lyu, A.; Zhang, B.; Yu, Y.; Zhang, G.
10.1101/2024.05.23.594910 — bioinformatics — Posted on 2024-05-28
621 Extensive collagen deposition by mesenchymal stem cells cultured in 3D self-assembled peptide scaffolds as revealed by nanoplasmonic colorimetric histology.
Chong, C. J. H.; Lim, V.; Charnley, M.; Ratcliffe, J.; Field, E.; Caballero-Aguilar, L. M.; Johnson, C.; Orian, J.; Caracciolo, K.; Balaur, E.; Abbey, B.; Moulton, S. E.; Binger, K. J.; Reynolds, N. P.
10.1101/2022.09.15.508197 — bioengineering — Posted on 2024-05-28
623 Comprehensive gene expression analysis of organoid-derived healthy human colonic epithelium and cancer cell line by stimulated with live probiotic bacteria
Sen, A.; Imai, A.; Miyauchi, E.; Yanagisawa, K.; Oda, T.; Sasaki, F.; Uchida, S.; Okada, T.; Yokobori, T.; Saeki, H.; Odamaki, T.; Sasaki, N.
10.1101/2024.05.23.595631 — ecology — Posted on 2024-05-28
624 Meta-analyses of Culex blood-meals indicates strong regional effect on feeding patterns
Griep, J. S.; Grant, E.; Pilgrim, J.; Riabinina, O.; Baylis, M.; Wardeh, M.; Blagrove, M. S. C.
10.1101/2024.05.24.595669 — ecology — Posted on 2024-05-28
626 Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation
Coux, R. X.; Dubois, A.; Chervova, A.; Festuccia, N.; Gonzalez, I.; Vandormael-Pournin, S.; Cohen-Tannoudji, M.; Navarro, P.
10.1101/2024.05.27.596047 — molecular biology — Posted on 2024-05-27
627 Thermal variation influences the transcriptome of the major malaria vector Anopheles stephensi.
Pathak, A. K.; Quek, S.; Sharma, R.; Shiau, J. C.; Thomas, M. B.; Hughes, G. L.; Murdock, C. C.
10.1101/2024.05.27.596085 — molecular biology — Posted on 2024-05-28
628 Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury
Moussavi-Harami, S. F.; Cleary, S. J.; Magnen, M.; Seo, Y.; Conrad, C.; English, B. C.; Qiu, L.; Wang, K. M.; Abram, C. L.; Lowell, C. A.; Looney, M. R.
10.1101/2024.05.23.595575 — immunology — Posted on 2024-05-28
629 RNA structure landscape of S. cerevisiae introns
Rangan, R.; Huang, R.; Hunter, O.; Pham, P.; Ares, M.; Das, R.
10.1101/2022.07.22.501175 — biochemistry — Posted on 2024-05-28
631 The importance of small island populations for the long term survival of endangered large-bodied insular mammals
Aninta, S. G.; Drinkwater, R.; Carmagnini, A.; Deere, N. J.; Priyono, D. S.; Andayani, N.; Winarni, N. L.; Supriatna, J.; Fumagalli, M.; Larson, G.; Galbusera, P.; Macdonald, A.; Greer, D.; Mohamad, K.; Prasetyaningtyas, W. E.; Mustari, A. H.; Williams, J.; Barnett, R.; Shaw, D.; Semiadi, G.; Burton, J.; Seaman, D.; Voigt, M.; Struebig, M.; Brace, S.; Rossiter, S.; Frantz, L.
10.1101/2024.05.23.595221 — evolutionary biology — Posted on 2024-05-27
632 Isotope geolocation and population genomics in Vanessa cardui: Short- and long-distance migrants are genetically undifferentiated
Reich, M. S.; Shipilina, D.; Talla, V.; Bahleman, F.; Kebe, K.; Berger, J. L.; Backström, N.; Talavera, G.; Bataille, C. P.
10.1101/2023.12.10.569105 — evolutionary biology — Posted on 2024-05-27
637 Molecular Display of the Animal Meta-Venome for Discovery of Novel Therapeutic Peptides
Hsiao, M.-H.; Miao, Y.; Liu, Z.; Schutze, K.; Limjunyawong, N.; Chien, D. C.-C.; Monteiro, W. D.; Chu, L.-S.; Morgenlander, W.; Jayaraman, S.; Jang, S.-e.; Gray, J. J.; Zhu, H.; Dong, X.; Steinegger, M.; Larman, H. B.
10.1101/2024.05.27.595990 — molecular biology — Posted on 2024-05-27
638 Genetically edited human placental organoids cast new light on the role of ACE2 in placental development
Arthurs, A. L.; Dietrich, B.; Knoefler, M.; Lushington, C. J.; Thomas, P. Q.; Adikusuma, F.; Jankovic-Karasoulos, T.; Smith, M. D.; Pringle, K. G.; Roberts, C. T.
10.1101/2024.05.09.592870 — molecular biology — Posted on 2024-05-28
642 Screening clinical Candida albicans isolates for invasiveness by mimicking the human environment
Vulin, C.; Sutter, J.; Schweizer, T. A.; Andreoni, F.; Baer, J.; Bernasconi, A.; Bulut, K.; Posteraro, B.; Sanguinetti, M.; Zinkernagel, A.
10.1101/2024.05.27.596042 — microbiology — Posted on 2024-05-27
644 Detection of a reassortant swine- and human-origin H3N2 influenza A virus in farmed mink in British Columbia, Canada
Kuchinski, K. S.; Tyson, J.; Lee, T.; Detmer, S.; Berhane, Y.; Burns, T.; Prystajecky, N. A.; Himsworth, C.
10.1101/2024.05.27.596080 — microbiology — Posted on 2024-05-27
647 A fungal endophyte induces local cell-wall mediated resistance in wheat roots against take-all disease
Chancellor, T.; Smith, D. P.; Chen, W.; Clark, S. J.; Venter, E.; Halsey, K.; Carrera, E.; McMillan, V.; Canning, G.; Armer, V.; Hammond-Kosack, K. E.; Palma-Guerrero, J.
10.1101/2023.11.23.568424 — plant biology — Posted on 2024-05-27
649 Chlamydia-driven ISG15 expression dampens the immune response of epithelial cells independently of ISGylation
Wu, Y.; Liu, C.; Tang, C.; Niragire, B.; Levy-Zauberman, Y.; Adapen, C.; Vernay, T.; Hugueny, J.; Baud, V.; Subtil, A.
10.1101/2024.05.27.596023 — microbiology — Posted on 2024-05-27
651 Towards a Health-Associated Core Keystone (HACK) index for the human gut microbiome
Goel, A.; Shete, O.; Goswami, S.; Samal, A.; CB, L.; Kedia, S.; Ahuja, V.; Shanahan, F.; O'Toole, P.; Ghosh, T. S.
10.1101/2024.05.27.596018 — microbiology — Posted on 2024-05-27
652 Molecular Signatures for Microbe-Associated Colorectal Cancers
Sayed, I. M.; Vo, D. T.; Alcantara, J.; Inouye, K. M.; Pranadinata, R. F.; Luo, L.; Boland, R. C.; Goyal, N. P.; Kuo, D. J.; Huang, S. C.; Sahoo, D.; Ghosh, P.; Das, S.
10.1101/2024.05.26.595902 — microbiology — Posted on 2024-05-27
653 The heme precursor 5-aminolevulinic acid triggers the shutdown of the HemKR signalling system in Leptospira
Imelio, J. A.; Trajtenberg, F.; Mondino, S.; Zarantonelli, L.; Vitrenko, I.; Lemee, L.; Cokelaer, T.; Picardeau, M.; Buschiazzo, A.
10.1101/2023.10.19.563136 — microbiology — Posted on 2024-05-27
654 Genital microbiota in infertile couples
Baud, D.; Peric, A.; Vidal, A.; Weiss, J.; Engel, P.; Das, S.; Stojanov, M.
10.1101/2023.06.14.544778 — microbiology — Posted on 2024-05-27
658 Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis
Seasock, M. J.; Shafiquzzaman, M.; Ruiz-Echartea, M. E.; Kanchi, R. S.; Tran, B. T.; Simon, L. M.; Meyer, M. D.; Erice, P. A.; Lotlikar, S. L.; Wenlock, S. C.; Ochsner, S. A.; Enright, A.; Carisey, A. F.; Romero, F.; Rosas, I. O.; King, K. Y.; McKenna, N. J.; Coarfa, C.; Rodriguez, A.
10.1101/2024.05.22.595205 — cell biology — Posted on 2024-05-27
662 Unifying the analysis of bottom-up proteomics data with CHIMERYS
Frejno, M.; Berger, M. T.; Tueshaus, J.; Hogrebe, A.; Seefried, F.; Graber, M.; Samaras, P.; Fredj, S. B.; Sukumar, V.; Eljagh, L.; Bronshtein, I.; Mamisashvili, L.; Schneider, M.; Gessulat, S.; Schmidt, T.; Kuster, B.; Zolg, D. P.; Wilhelm, M.
10.1101/2024.05.27.596040 — biochemistry — Posted on 2024-05-27
663 Strong conservation of spacer lengths in NrdR repressor DNA binding sites
Shahid, S.; Balka, M.; Lundin, D.; Daley, D. O.; Sjoberg, B.-M.; Rozman Grinberg, I.
10.1101/2024.05.27.596032 — biochemistry — Posted on 2024-05-27
664 Engineering cardiolipin binding to an artificial membrane protein
Abramsson, M. L.; Corey, R. A.; Skerle, J. L.; Persson, L. J.; Anden, O.; Oluwole, A. O.; Howard, R. J.; Lindahl, E.; Robinson, C. V.; Strisovsky, K.; Marklund, E. G.; Drew, D.; Stansfeld, P. J.; Landreh, M.
10.1101/2024.05.27.592301 — biochemistry — Posted on 2024-05-27
668 The role of the Frontal Aslant tract in bilingual language control
Quartarone, C.; Navarrete, E.; Gastaldon, S.; Budisavljevic, S.; Peressotti, F.
10.1101/2023.02.01.526563 — neuroscience — Posted on 2024-05-27
669 Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep
Turi, G. F.; Teng, S.; Chen, X.; Lim, E. C.; Dias, C.; Hu, R.; Wang, R.; Zhen, F.; Peng, Y.
10.1101/2023.05.12.540575 — neuroscience — Posted on 2024-05-27
671 Repetitive mild closed-head injury induced synapse loss and increased local BOLD-fMRI signal homogeneity
Markicevic, M.; Mandino, F.; Toyonaga, T.; Cai, Z.; Fesharaki-Zadeh, A.; Shen, X.; Strittmatter, S. M.; Lake, E. M.
10.1101/2024.05.24.595651 — neuroscience — Posted on 2024-05-27
675 Predicting the infecting dengue serotype from antibody titre data using machine learning
Cracknell Daniels, B.; Buddhari, D.; Hunsawong, T.; Iamsirithaworn, S.; Farmer, A. R.; Cummings, D. A. T.; Anderson, K. B.; Dorigatti, I.
10.1101/2024.05.23.595461 — immunology — Posted on 2024-05-27
676 Targeting a shared neoepitope derived from non-canonical translation of c-MYC oncogene in cancer cells
Depil, S.; Baulu, E.; Bolon, A.; Etchegaray, E.; Raimundo, F.; Merienne, A.; Martin, J.; Grandsire, J.; Richard, T.; Tonon, L.; Dubois, C.; Estornes, Y.; Boulos, R.; Tabone, O.; Bonaventura, P.; Page, A.; Gardet, C.; Alcazer, V.; Hughes, S.; Gillet, B.; Gervois, N.; Labarriere, N.; Wang, Q.; Valladeau-Guilemond, J.; Chuvin, N.; Marcel, V.; Diaz, J.-J.
10.1101/2024.05.23.595486 — immunology — Posted on 2024-05-27
678 Exploring Pharmacogenetic Factors Influencing Hydroxyurea Response in Tanzanian Sickle Cell Disease Patients: A Genomic Medicine Approach.
Nkya, S.; Nzunda, C.; Saukiwa, E.; Kaywanga, F.; Buberwa, E.; Solomon, D.; Christopher, H.; Ngowi, D.; Johansen, J.; Urio, F.; Mgaya, J.; Kindole, C.; Yonazi, M.; Karim, S.; Alimohamed, M. Z.; Sangeda, R.; Chamba, C.; Dandara, C.; Novelli, E.; Chimusa, E.; Makani, J.
10.1101/2024.05.23.595488 — genomics — Posted on 2024-05-27
679 Characterization of immunity-inducing rhizobacteria highlights diversity in plant-microbe interactions
Loranger, M. E.; Yim, W.; Toffoli, M.; Groleau, M.-C.; Nickzad, A.; Morales-Lizcano, N.; Berleth, T.; Moeder, W.; Deziel, E.; Yoshioka, K.
10.1101/2024.05.23.595641 — plant biology — Posted on 2024-05-27
680 A functional approach to homeostatic regulation
Fernandez Arias, C.; Acosta, F. J.; Bertocchini, F.; Fernandez-Arias, C.
10.1101/2024.05.22.595277 — physiology — Posted on 2024-05-27
681 The differential virulence of Fusarium oxysporum strains causing corneal infections and plant diseases is associated with accessory chromosome composition
Ayhan, D. H.; Abbodante, S.; Martinez Soto, D.; Milo Cochavi, S.; Rickelton, K.; Kotera, S.; Sohrab, V.; Arie, T.; Marshall, M. E.; Rocha, M. C.; Haridas, S.; Grigoriev, I.; Shlezinger, N.; Pearlman, E. S.; Ma, L.-J.
10.1101/2024.05.23.595639 — microbiology — Posted on 2024-05-27
686 A PI(3,5)P2/ESCRT-III axis terminates STING signalling by facilitating TSG101-mediated lysosomal microautophagy
Taguchi, T.; Shoji, T.; Shinojima, A.; Kusumi, S.; Koga, D.; Mukai, K.; Nakayama, J.; Higashiyama, S.; Kuchitsu, Y.
10.1101/2024.05.26.595979 — cell biology — Posted on 2024-05-27
687 Mild hyperthermia-induced thermogenesis in the endoplasmic reticulum defines stress response mechanisms
Dukic, B.; Ruppert, Z.; Toth, M. E.; Hunya, A.; Czibula, A.; Biro, P.; Tiszlavicz, A.; Peter, M.; Balogh, G.; Erdelyi, M.; Timinszky, G.; Vigh, L.; Gombos, I.; Torok, Z.
10.1101/2024.05.24.595680 — cell biology — Posted on 2024-05-27
690 GSK-3alpha-BNIP3 axis promotes mitophagy in human cardiomyocytes under hypoxia
Marzook, H.; Gupta, A.; Jayakumar, M. N.; Saleh, M. A.; Tomar, D. N.; Qaisar, R.; Ahmad, F.
10.1101/2024.05.24.595650 — cell biology — Posted on 2024-05-27
691 Epidermal Growth Factor Receptor Regulates Beclin-1 in Hyperoxia
Harris, Z.; Korde, A.; Khoury, J.; Manning, E.; Stanley, G.; Sun, Y.; Hu, B.; Shin, H. J.; Joerns, J.; Clark, B.; Placek, L.; Unutmaz, D.; Chun, H.; Sharma, L.; Sauler, M.; Rajagopalan, G.; Zhang, X.; Wang, H.; Kang, M.-J.; Koff, J.
10.1101/2024.05.24.595621 — cell biology — Posted on 2024-05-27
694 Performance effects from different shutdown methods of three electrode materials for the power-to-gas application with electromethanogenesis
Rohbohm, N.; Lang, M.; Erben, J.; Gemeinhardt, K.; Patel, N.; Ilic, I. K.; Hafenbradl, D.; Rodrigo Quejigo, J.; Angenent, L. T.
10.1101/2024.05.22.595300 — bioengineering — Posted on 2024-05-27
695 IQCH regulates spermatogenesis by interacting with CaM to promote the expression of RNA-binding proteins
Ruan, T.; Zhou, R.; Yang, Y.; Guo, J.; Jiang, C.; Wang, X.; Shen, G.; Dai, S.; Chen, S.; Shen, Y.
10.1101/2023.06.23.546221 — genetics — Posted on 2024-05-27
696 Nanoscale analysis of human G1 and metaphase chromatin in situ
Chen, J. K.; Liu, T.; Cai, S.; Ruan, W.; Ng, C. T.; Shi, J.; Surana, U.; Gan, L.
10.1101/2023.07.31.551204 — cell biology — Posted on 2024-05-27
697 Pollination and mating traits underlie diverse reproductive strategies in flowering plants
Helmstetter, A. J.; Mendez, M.; Schonenberger, J.; Burgarella, C.; Anderson, B.; Balthazar, M. v.; Billiard, S.; Boer, H. d.; Cros, J.; Delecroix, P.-A.; Dufay, M.; Pannell, J.; Savova Bianchi, D.; Schoen, D.; Vallejo-Marin, M.; Zenil-Ferguson, R.; Sauquet, H.; Glemin, S.; Kafer, J.
10.1101/2024.02.26.582019 — evolutionary biology — Posted on 2024-05-27
700 Spatiotemporal resonance in mouse primary visual cortex
Gulbinaite, R.; Nazari, M.; Rule, M. E.; Bermudez Contreras, E. J.; Cohen, M. X.; Mohajerani, M. H.; Heimel, J. A.
10.1101/2023.07.31.551212 — neuroscience — Posted on 2024-05-27
701 Dynamic Network Analysis of Electrophysiological Task Data
Gohil, C.; Kohl, O.; Huang, R.; van Es, M. W. J.; Parker Jones, O.; Hunt, L. T.; Quinn, A. J.; Woolrich, M. W.
10.1101/2024.01.12.567026 — neuroscience — Posted on 2024-05-27
702 Cognitive Phenotype Shifts in Risk-Taking: Interplay of Non-Suicidal Self-Injury Behaviors and Intensified Depression
Lu, Y.-L.; Ge, Y.; Li, M.; Liang, S.; Zhang, X.; Sui, Y.; Yang, L.; Li, X.; Zhang, Y.; Zhang, H.; Yan, H.
10.1101/2023.12.10.570987 — neuroscience — Posted on 2024-05-27
705 Chromatin enhancer activity of IκBα mediates the exit from naïve pluripotency
Palma, L. G.; Alvarez-Villanueva, D.; Maqueda, M.; Barrero, M.; IGLESIAS, A.; Bertran, j.; ALVAREZ, D.; GARCIA-PRIETO, C.; BALLARE, C.; RODRIGUEZ-CORTEZ, V.; BUENO, C.; VIDAL, A.; Villanueva, A.; Menendez, P.; Stik, G.; Di Croce, L.; Payer, B.; Esteller, M.; Espinosa, L.; Bigas, A.
10.1101/2023.07.28.550934 — cell biology — Posted on 2024-05-27
706 Tagless LysoIP method for molecular profiling of lysosomal content in clinical samples
Saarela, D.; Lis, P.; Gomes, S.; Nirujogi, R. S.; Dong, W.; Rawat, E.; Glendinning, S.; Zeneviciute, K.; Bagnoli, E.; Fasimoye, R.; Lin, C.; Nyame, K.; Boros, F. A.; Zunke, F.; Lamoliatte, F.; Elshani, S.; Jaconnelli, M.; Jans, J. J. M.; Huisman, M. A.; Posern, C.; Westermann, L. M.; Schulz, A.; van Hasselt, P. M.; Alessi, D. R.; Abu-Remaileh, M.; Sammler, E.
10.1101/2024.05.17.594681 — cell biology — Posted on 2024-05-27
708 Dimensions of early life adversity are differentially associated with patterns of delayed and accelerated brain maturation
Beck, D.; Whitmore, L.; MacSweeney, N.; Brieant, A.; Karl, V.; de Lange, A.-M. G.; Westlye, L. T.; Mills, K. L.; Tamnes, C. K.
10.1101/2024.01.22.576780 — neuroscience — Posted on 2024-05-27
709 Staying in control: characterising the mechanisms underlying cognitive control in high and low arousal states
Alameda, C.; Avancini, C.; Sanabria, D.; Bekinschtein, T. A.; Canales-Johnson, A.; Ciria, L. F.
10.1101/2023.04.17.536548 — neuroscience — Posted on 2024-05-27
710 Characterization of the small Arabidopsis thaliana GTPase and ADP-ribosylation factor-like 2 protein TITAN5
Mohr, I.; Mirzaiebadizi, A.; Sanyal, S.; Chuenban, P.; Ahmadian, M. R.; Ivanov, R.; Bauer, P.
10.1101/2023.04.27.538563 — plant biology — Posted on 2024-05-27
711 Delineating neural contributions to electroencephalogram-based speech decoding
Sato, M.; Kabe, Y.; Nobe, S.; Yoshida, A.; Inoue, M.; Shimizu, M.; Tomeoka, K.; Sasai, S.
10.1101/2024.05.09.591996 — neuroscience — Posted on 2024-05-27
713 Conserved Cis-Acting Range Extender Element Mediates Extreme Long-Range Enhancer Activity in Mammals
Bower, G.; Hollingsworth, E.; Jacinto, S.; Clock, B.; Cao, K.; Liu, M.; Dziulko, A.; Alcaina-Caro, A.; Xu, Q.; Skowronska-Krawczyk, D.; Lopez-Rios, J.; Dickel, D.; Bardet, A.; Pennacchio, L.; Visel, A.; Kvon, E.
10.1101/2024.05.26.595809 — genomics — Posted on 2024-05-27
714 A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens
Reiner, B. C.; Chehimi, S. N.; Merkel, R.; Toikumo, S.; Berrettini, W. H.; Kranzler, H. R.; Sanchez-Roige, S.; Kember, R. L.; Schmidt, H. D.; Crist, R. C.
10.1101/2024.05.26.595949 — genetics — Posted on 2024-05-26
716 Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution
Yang, L.; Fang, L. Z.; Lynch, M. R.; Xu, C. S.; Hahm, H.; Zhang, Y.; Heitmeier, M. R.; Costa, V.; Samineni, V. K.; Creed, M. C.
10.1101/2024.05.24.595793 — neuroscience — Posted on 2024-05-27
717 Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia
Sun, N.; Sun, Y.-Y.; Cao, R.; Chen, H.-R.; Wang, Y.; Fugate, E.; Smucker, M. R.; Kuo, Y.-M.; Grant, P. E.; Lindquist, D. M.; Kuan, C.-Y.; Hu, S.
10.1101/2021.11.29.470404 — neuroscience — Posted on 2024-05-27
718 Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory
Yamawaki, N.; Login, H.; Feld-Jakobsen, S. O.; Molnar, B. M.; Kirkegaard, M. Z.; Moltesen, M.; Okrasa, A.; Radulovic, J.; Tanimura, A.
10.1101/2024.03.17.585387 — neuroscience — Posted on 2024-05-27
719 Transarterial Embolization Using a Liquid Embolic Enhances Tumor Necrosis to Enable Improved Efficacy Compared with a Particle Embolic in a Translational Rat Model of Hepatocellular Carcinoma
Gurevich, A.; Islam, A.; Wakim, J.; Yarsky, E.; Kiefer, R.; El-Ghazal, R.; McClung, G.; Cormode, D. P.; Nadolski, G. J.; Avritscher, R.; Hunt, S. J.; Gade, T. P. F.
10.1101/2024.05.23.595637 — cancer biology — Posted on 2024-05-26
720 ALDH1A3-acetaldehyde metabolism potentiates transcriptionalheterogeneity in melanoma
Lu, Y.; Travnickova, J.; Badonyi, M.; Rambow, F.; Coates, A.; Khan, Z.; Marques, J.; Murphy, L.; Garcia-Martinez, P.; Marais, R.; Louphrasitthiphol, P.; Chan, A. H. Y.; Schofield, C. J.; Kriegsheim, A. V.; Marsh, J. A.; Pavet, V.; Sansom, O. J.; Illingworth, R. S.; Patton, E. E.
10.1101/2023.10.28.564337 — cancer biology — Posted on 2024-05-26
721 The maternal vGluT2 and embryonic mGluR3 signaling relay system controls offspring wing dimorphism in pea aphid
Yuan, Y.; Wang, Y.; Ye, W.; Xie, L.; Yuan, E.; Guo, H.; Wang, S.; Dong, F.; Zhu-Salzman, K.; Ge, F.; Sun, Y.
10.1101/2024.05.22.595290 — zoology — Posted on 2024-05-26
723 Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia
Abou Alaiwa, M. H.; Hilkin, B. M.; Price, M. P.; Gansemer, N. D.; Rector, M. R.; Stroik, M. R.; Powers, L. S.; Whitworth, K. M.; Samuel, M. S.; Jain, A.; Ostedgaard, L. S.; Ernst, S. E.; Philibert, W.; Boyken, L. D.; Moninger, T. O.; Karp, P. H.; Hornick, D. B.; Sinn, P. L.; Fischer, A. J.; Pezzulo, A. A.; McCray, P. B.; Meyerholz, D. K.; Zabner, J.; Prather, R. S.; Welsh, M. J.; Stoltz, D. A.
10.1101/2024.05.22.594822 — physiology — Posted on 2024-05-26
724 Effect of senolytic drugs in young female mice chemically induced to estropause
Avila, B. M.; Zanini, B. M.; Ludovico, K. P.; Hense, J. D.; Garcia, D. N.; Prosczek, J.; Stefanello, F. M.; da Cruz, P. H.; Giongo, J. L.; Vaucher, R. A.; Mason, J. B.; Masternak, M. M.; Schneider, A.
10.1101/2024.05.22.595355 — physiology — Posted on 2024-05-26
727 Functions of the AP2/ERF family transcription factor AIL7 in immunity against soilborne clubroot pathogen in Arabidopsis
Jayawardhane, K.; Somarathna, T.; Manoli, V. P.; Hwang, S.-F.; Strelkov, S. E.; Singer, S. D.; Chen, G. G.
10.1101/2024.05.22.595381 — pathology — Posted on 2024-05-26
737 Inherent Metabolic Adaptations in Adult Spiny Mouse (Acomys) Cardiomyocytes Facilitate Enhanced Cardiac Recovery Following Myocardial Infarction
Kuppa, A.; Alzamrooni, A.; Suhan, T.; Chaudhary, R.; Lopez, R.; Collins, N.; Van Den Bergh, F.; Abouleisa, R.; Wang, H.; Mohamed, T.; Satin, J.; Lyssiotis, C. A.; Beard, D.; Abdel-Latif, A.
10.1101/2024.05.22.595229 — cell biology — Posted on 2024-05-26
739 Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages
Lim, P. N.; Cervantes, M. M.; Pham, L. K.; Doherty, S.; Tufts, A.; Dubey, D.; Mai, D.; Aderem, A.; Diercks, A. H.; Rothchild, A. C.
10.1101/2024.05.22.594428 — immunology — Posted on 2024-05-26
740 A Rigorous Multi-Laboratory Study of Known PDAC Biomarkers Identifies Increased Sensitivity and Specificity Over CA19-9 Alone
Haab, B.; Qian, L.; Staal, B.; Jain, M.; Fahrmann, J. F.; Worthington, C.; Prosser, D.; Velikokhatnaya, L.; Lopez, C.; Tang, R.; Hurd, M.; Gopalakrishnan, N.; Kumar, S.; Smith, L.; Hanash, S.; Batra, S. K.; Maitra, A.; Lokshin, A.; Huang, Y.; Brand, R.
10.1101/2024.05.22.595399 — cancer biology — Posted on 2024-05-26
743 Rationally Minimizing Natural Product Libraries Using Mass Spectrometry
Ness, M.; Peramuna, T.; Wendt, K. L.; Collins, J. E.; King, J. B.; Paes, R.; Santos, N. M.; Okeke, C.; Miller, C. R.; Chakrabarti, D.; Cichewicz, R. H.; McCall, L.-I.
10.1101/2024.05.22.595232 — bioinformatics — Posted on 2024-05-26
744 CosGeneGate Selects Multi-functional and Credible Biomarkers for Single-cell Analysis
Liu, T.; Long, W.; Cao, Z.; Wang, Y.; He, C. H.; Zhang, L.; Strittmatter, S. M.; Zhao, H.
10.1101/2024.05.22.595428 — bioinformatics — Posted on 2024-05-26
745 A generative foundation model for antibody sequence understanding
Barton, J.; Gaspariunas, A.; Yadin, D. A.; Dias, J.; Nice, F. L.; Minns, D. H.; Snudden, O.; Povall, C.; Valle Tomas, S.; Dobson, H.; Farmery, J. H.; Leem, J.; Galson, J. D.
10.1101/2024.05.22.594943 — bioinformatics — Posted on 2024-05-26
746 Causal network perturbation analysis identifies known and novel type-2 diabetes driver genes
Zhao, Y.; Aman, A.; Kumar, P.; Mahoney, J. M.; He, H.; Baker, C.; George, J.; Li, S.
10.1101/2024.05.22.595431 — bioinformatics — Posted on 2024-05-26
749 Timing antigenic escape in multiple myeloma treated with T-cell redirecting immunotherapies
Papadimitriou, M.; Ahn, S.; Diamond, B.; Lee, H.; McIntyre, J.; Truger, M.; Durante, M.; Ziccheddu, B.; Landgren, O.; Rasche, L.; Bahlis, N.; Neri, P.; Maura, F.
10.1101/2024.05.22.595383 — genomics — Posted on 2024-05-26
751 Brown Adipose Tissue and Skeletal Muscle Coordinately Contribute to Thermogenesis in Mice
Sakaue, H.; Izumi-Mishima, Y.; Tsutsumi, R.; Shiuchi, T.; Fujimoto, S.; Taniguchi, M.; Okamatsu-Ogura, Y.; Yoneshiro, T.; Kuroda, M.; Nomura, K.
10.1101/2024.05.26.595945 — molecular biology — Posted on 2024-05-26
752 Granzyme K drives a newly-intentified pathway of complement activation
Donado, C. A.; Jonsson, A. H.; Theisen, E.; Zhang, F.; Nathan, A.; Rupani, K.; Jones, D.; Accelerating Medicines Partnership RA/SLE Network, ; Raychaudhuri, S.; Dwyer, D. F.; Brenner, M. B.
10.1101/2024.05.22.595315 — immunology — Posted on 2024-05-26
755 Genesis: A Modular Protein Language Modelling Approach to Immunogenicity Prediction
O'Brien, H.; Salm, M.; Morton, L. T.; Szukszto, M.; O'Farrell, F.; Boulton, C.; King, L.; Bola, S. K.; Becker, P.; Craig, A.; Nielsen, M.; Samuels, Y.; Swanton, C.; Mansour, M. R.; Hadrup, S. R.; Quezada, S.
10.1101/2024.05.22.595296 — bioinformatics — Posted on 2024-05-26
756 Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI
Mandino, F.; Horien, C.; Shen, X.; Desrosier-Gregoire, G.; Luo, W.; Markicevic, M.; Constable, R. T.; Papademetris, X.; Chakravarty, M.; Betzel, R.; Lake, E. M.
10.1101/2024.05.24.594620 — neuroscience — Posted on 2024-05-26
758 Hippocampal mGluR5 levels are comparable in Alzheimer's and control brains, and divergently influenced by amyloid and tau in control brain
Wang, J.; Savodalli, S.; Kong, Y.; Mashio, C.; Konietzko, U.; Klohs, J.; Razansky, D.; Rominger, A.; Mu, L.; Schibli, R.; Hock, C.; Nitsch, R. M.; Ni, R.
10.1101/2024.05.25.595868 — neuroscience — Posted on 2024-05-26
759 Early life intestinal inflammation alters gut microbiome, impairing gut-brain communication and reproductive behavior in mice
Sullivan, O.; Sie, C.; Ng, K. M.; Cotton, S.; Rosete, C.; Hamden, J. E.; Singh, A. P.; Lee, K.; Kim, J.; Yu, H.; Clayton, C.; Garcia, N. A. C.; Voznyuk, K.; Choudhary, J.; Plett, N.; Arora, S.; Ghezzi, H.; Huan, T.; Soma, K. K.; Yu, J.-P. J.; Tropini, C.; Ciernia, A. V.
10.1101/2024.05.23.595618 — neuroscience — Posted on 2024-05-26
760 Molecular Specializations Underlying Phenotypic Differences in Inner Ear Hair Cells of Zebrafish and Mice
Giffen, K.; Liu, H.; Yamane, K. L.; Li, Y.; Chen, L.; Kramer, K. L.; Zallocchi, M.; He, D. Z. Z.
10.1101/2024.05.24.595729 — neuroscience — Posted on 2024-05-26
761 Angiogenesis in the mature mouse cortex is governed in a region specific and Notch1 dependent manner
Raudales, A.; Schager, B.; Hancock, D.; Sharma, S.; Narayana, K.; Reeson, P.; Cheema, M. S.; Korbelin, J.; Brown, C. E.
10.1101/2024.05.24.595778 — neuroscience — Posted on 2024-05-26
762 Immunomodulatory Role of the Stem Cell Circadian Clock in Muscle Repair
Peek, C. B.; Zhu, P.; Pfrender, E.; Steffeck, A.; Reczek, C.; Zhou, Y.; Thakkar, A.; Gupta, N.; Willbanks, A.; Lieber, R.; Roy, I.; Chandel, N. S.
10.1101/2024.05.24.595728 — developmental biology — Posted on 2024-05-26
765 Characterization of sleep in a mouse model of CLN3 disease revealed sex-specific sleep disturbances
Kane, K. M.; Iradukunda, D.; McLouth, C. J.; Guo, L. Z.; Wang, J.; Subramoniam, A.; Huffman, D.; Donohue, K. D. M.; O'Hara, B. F.; Sunderam, S.; Wang, Q. J.
10.1101/2024.05.24.595712 — neuroscience — Posted on 2024-05-26
768 The UFMylation pathway is impaired in Alzheimer's disease
Yan, T.; Heckman, M. G.; Craver, E. C.; Liu, C.-C.; Rawlinson, B. D.; Wang, X.; Murray, M. E.; Dickson, D. W.; Ertekin-Taner, N.; Lou, Z.; Bu, G.; Springer, W.; Fiesel, F. C.
10.1101/2024.05.24.595755 — neuroscience — Posted on 2024-05-26
772 Senescent-like microglia limit remyelination through the senescence associated secretory phenotype
Gross, P. S.; Laforet, V. D.; Manavi, Z.; Zia, S.; Lee, S. H.; Shults, N. V.; Selva, S.; Alvarez, E.; Plemel, J. R.; Schafer, D. P.; Huang, J. K.
10.1101/2024.05.23.595605 — neuroscience — Posted on 2024-05-26
773 Tonotopy is not preserved in a descending stage of auditory cortex
Gu, M.; Liang, S.; Zhu, J.; Li, R.; Liu, K.; Wang, X.; Ohl, F. W.; Zhang, Y.; Liao, X.; Zhang, C.; Jia, H.; Zhou, Y.; Zhang, J.; Chen, X.
10.1101/2024.05.25.595883 — neuroscience — Posted on 2024-05-26
776 CRASH2p: Closed-loop Two Photon Imaging in Freely Moving Animals
McNulty, P.; Wu, R.; Yamaguchi, A.; Heckscher, E. H.; Haas, A.; Nwankpa, A.; Skanata, M. M.; Gershow, M. H.
10.1101/2024.05.22.595209 — neuroscience — Posted on 2024-05-26
780 A cortical locus for modulation of arousal states
Chintalacheruvu, N.; Kalelkar, A.; Boutin, J.; Breton-Provencher, V.; Huda, R.
10.1101/2024.05.24.595859 — neuroscience — Posted on 2024-05-26
782 Deep Learning Detection of Subtle Torsional Eye Movements: Preliminary Results
Mukunda, K. N.; Ye, T.; Luo, Y.; Zoitou, A.; Kwon, K. E.; Singh, R.; Woo, J.; Sivakumar, N.; Greenstein, J. L.; Taylor, C. O.; Kheradmand, A.; Green, K. E.
10.1101/2024.05.26.595236 — neuroscience — Posted on 2024-05-26
783 lncRNA ADEPTR loss-of-function elicits sex-specific behavioral and spine deficits
Chanda, K.; Carter, J. P.; Nishizono, H.; Raveendra, B. L.; Brantley, A.; Grinman, E.; Espadas, I.; Lozano-Villada, S.; Wingfield, J.; Wagner, G.; Peterson, A.; Yasuda, R.; Puthanveettil, S.
10.1101/2024.05.25.595903 — neuroscience — Posted on 2024-05-26
784 Heartbeat perception is causally linked to frontal delta oscillations
Haslacher, D.; Reber, P.; Cavallo, A.; Rosenthal, A.; Pangratz, E.; Beck, A.; Romanczuk Seiferth, N.; Nikulin, V.; Villringer, A.; Soekadar, S.
10.1101/2024.05.25.595873 — neuroscience — Posted on 2024-05-26
787 Complimentary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome
Lee, K.-H.; Stafford, A. M.; Pacheco-Vergara, M.; Cichewicz, K.; Canales, C. P.; Seban, N.; Corea, M.; Rahbarian, D.; Bonekamp, K. E.; Gillie, G. R.; Pacheco-Cruz, D.; Gill, A. M.; Hwang, H.-E.; Uhl, K.; Shinawi, M.; Li, X.; Obenaus, A.; Crandall, S. R.; Jeong, J.; Nord, A. S.; Kim, C.-H.; Vogt, D.
10.1101/2024.05.26.595966 — neuroscience — Posted on 2024-05-26
788 A microglia-containing cerebral organoid model to study early life immune challenges
Buonfiglioli, A.; Kübler, R.; Missall, R.; De Jong, R.; Chan, S.; Haage, V.; Wendt, S.; Lin, A. J.; Mattei, D.; Graziani, M.; Latour, B.; Gigase, F.; Nygaard, H. B.; De Jager, P. L.; De Witte, L. D.
10.1101/2024.05.24.595814 — neuroscience — Posted on 2024-05-26
789 RF coil design strategies for improving SNR at theultrahigh magnetic field of 10.5 Tesla
Waks, M.; Lagore, R. L.; Auerbach, E.; Grant, A.; Sadeghi-Tarakameh, A.; DelaBarre, L.; Jungst, S.; Tavaf, N.; Lattanzi, R.; Giannakopoulos, I.; Moeller, S.; Wu, X.; Yacoub, E.; Vizioli, L.; Schmidt, S.; Metzger, G.; Eryaman, Y.; Adriany, G.; Ugurbil, K.
10.1101/2024.05.23.595628 — neuroscience — Posted on 2024-05-26
795 Multiplexed single cell transcriptomics optimizes mesodermal patterning and hemogenic endothelial output from murine embryonic stem cells
Varnum-Finney, B.; Heck, A. M.; Srivatsan, S.; Dozono, S.; Wellington, R.; Nourigat-McKay, C.; Dignum, T.; Trapnell, C.; Hadland, B.
10.1101/2024.05.24.595249 — developmental biology — Posted on 2024-05-26
800 To be unique or blend in: dynamics of male African elephant character durability across time and social contexts
O'Connell-Rodwell, C. E.; Berezin, J. L.; Kinzley, C.; Freeman, P. T.; Sandri, M. N.; Kieschnick, D.; Abarca, M.; Hayssen, V.
10.1101/2024.05.24.595367 — animal behavior and cognition — Posted on 2024-05-26
802 Marsupial single-cell transcriptomics provides an atlas of developmental heterochrony
Menchero, S.; Barrington, C.; Alanis-Lobato, G.; Varsally, W.; Niakan, K. K.; Turner, J. M. A.
10.1101/2024.05.26.595746 — developmental biology — Posted on 2024-05-26
803 BMP signaling promotes heart regeneration via alleviation of replication stress
Dalvoy Vasudevarao, M.; Posadas-pena, D. S.; Ihle, M.; Bongiovanni, C.; Maity, P.; Redaelli, S.; Happ, K.; Geissler, D.; Mohammadi, H. F.; Rall-Scharpf, M.; Wu, C.-C.; Beisaw, A.; Scharffetter-Kochanek, K.; D'Uva, G.; Wiesmueller, L.; Weidinger, G.
10.1101/2024.05.24.595503 — developmental biology — Posted on 2024-05-26
804 Predicting and Shaping Human-Machine Interactions in Closed-loop, Co-adaptive Neural Interfaces
Madduri, M. M.; Yamagami, M.; Li, S. J.; Burckhardt, S.; Burden, S. A.; Orsborn, A. L.
10.1101/2024.05.23.595598 — neuroscience — Posted on 2024-05-26
806 Classification of psychedelic drugs based on brain-wide imaging of cellular c-Fos expression
Aboharb, F.; Davoudian, P. A.; Shao, L.-X.; Liao, C.; Rzepka, G. N.; Wojtasiewicz, C.; Dibbs, M.; Rondeau, J.; Sherwood, A. M.; Kaye, A. P.; Kwan, A. C.
10.1101/2024.05.23.590306 — neuroscience — Posted on 2024-05-26
810 APP-KI mice do not display the hallmark age-dependent cognitive decline of amyloid diseases
Blackmer-Raynolds, L.; Lipson, L. D.; Fraccaroli, I.; Krout, I. N.; Chan, J.; Sampson, T. R.
10.1101/2024.05.24.595745 — neuroscience — Posted on 2024-05-26
811 Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death.
Martinez, P.; Silva, M.; Abarzua, S.; Tevy, F.; Jaimovich, E.; Constantine-Paton, M.; Bustos, F. J.; van Zundert, B.
10.1101/2024.05.24.595817 — neuroscience — Posted on 2024-05-26
813 SASH1 impairs melanin synthesis and metastasis by down-regulating the TGF-β signaling pathway
Cui, H.; Wang, Q.; Liang, H.; Zhang, Y.; Liang, B.; Wang, W.; Ge, S.; He, H.; Ren, X.; Su, Z.; Guo, S.
10.1101/2024.05.22.595382 — cell biology — Posted on 2024-05-26
814 OPTIMIZATION OF DRIED BLOOD SPOT ASSAYS FOR HEPATITIS B VIRUS SURFACE ANTIBODY QUANTIFICATION
Motshosi, P.; Phinius, B. B.; Jongman, M.; Baruti, K.; Bhebhe, L.; Choga, W. T.; Moyo, S.; Gaseitsiwe, S.; Anderson, M.
10.1101/2024.05.23.595500 — microbiology — Posted on 2024-05-26
818 Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
Kucukoglu, B.; Mohammed, I.; Guerrero-Ferreira, R. C.; Kube, M.; Radecke, J.; Ribet, S.; Varnavides, G.; Leidl, M. L.; Lau, K.; Nazarov, S.; Myasnikov, A.; Sachse, C.; Mueller-Caspary, K.; Ophus, C.; Stahlberg, H.
10.1101/2024.02.12.579607 — biophysics — Posted on 2024-05-26
824 gRNAde: Geometric Deep Learning for 3D RNA inverse design
Joshi, C. K.; Jamasb, A. R.; Vinas, R.; Harris, C.; Mathis, S. V.; Morehead, A.; Anand, R.; Lio, P.
10.1101/2024.03.31.587283 — bioinformatics — Posted on 2024-05-25
826 An atlas of expressed transcripts in the prenatal and postnatal human cortex
Bamford, R.; Leung, S. K.; Chundru, V. K.; Jeffries, A. R.; Davies, J.; Franklin, A.; Chen, X.; McQuillin, A.; Bass, N.; APEX Consortium, ; Walker, E.; ONeill, P. A.; Pishva, E.; Dempster, E.; Hannon, E.; Wright, C.; Mill, J.
10.1101/2024.05.24.595768 — genomics — Posted on 2024-05-26
828 Collective responses of flocking sheep to a herding dog
Jadhav, V.; Pasqua, R.; Zanon, C.; Roy, M.; Tredan, G.; Bon, R.; Guttal, V.; Theraulaz, G.
10.1101/2024.05.24.595762 — animal behavior and cognition — Posted on 2024-05-26
831 Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution
Fang, L. Z.; Yang, L.; Lynch, M. R.; Xu, C. S.; Hahm, H.; Zhang, Y.; Heitmeier, M. R.; Costa, V.; Samineni, V. K.; Creed, M. C.
10.1101/2024.05.24.595793 — neuroscience — Posted on 2024-05-26
832 tRNA modifications tune decoding of codon pairs to prevent cellular quality control responses
Wu, J.; Eggers, C.; Sin, O.; Koziej, L.; Mancilla, H.; Mollet, F.; Scholer, H. R.; Drexler, H. C.; Ranff, T.; Fufezan, C.; Kraft, C.; Glatt, S.; Bruder, J. M.; Leidel, S. A.
10.1101/2024.02.27.582385 — biochemistry — Posted on 2024-05-25
836 Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies
Markusson, S.; Raasakka, A.; Schröder, M.; Sograte-Idrissi, S.; Rahimi, A. M.; Asadpour, O.; Körner, H.; Lodygin, D.; Eichel-Vogel, M. A.; Chowdhury, R.; Sutinen, A.; Iyer, M.; Cooper, M. H.; Weigel, M. K.; Ambiel, N.; Werner, H. B.; Zuchero, J. B.; Opazo, F.; Kursula, P.
10.1101/2024.05.25.595513 — biochemistry — Posted on 2024-05-25
844 Genome-wide sweeps create fundamental ecological units in the human gut microbiome
Yu, X. A.; Strachan, C. R.; Herbold, C. W.; Lang, M.; Gasche, C.; Makristathis, A.; Segata, N.; Pollak, S.; Tett, A.; Polz, M. F.
10.1101/2024.05.25.595854 — microbiology — Posted on 2024-05-25
846 Comparative analysis of tardigrade locomotion across life stage, species, and pharmacological treatment
Anderson, E. M.; Houck, S. G.; Conklin, C. L.; Tucci, K. L.; Rodas, J. D.; Mori, K. E.; Armstrong, L. J.; Illingworth, V. B.; Lo, T.-W.; Woods, I. G.
10.1101/2024.05.24.595396 — animal behavior and cognition — Posted on 2024-05-25
848 Post-transcriptional regulation of insulin mRNA storage by G3BP1/2+ condensates in beta cells
Quezada, E.; Vasiljevic, J.; Pal, A.; Münster, C.; Friedland, D.; Schöniger, E.; Sönmez, A.; Seiler, A.; Roch, P.; Wegbrod, C.; Ganss, K.; Knoch, K.-P.; Kipke, N.; Alberti, S.; Nano, R.; Piemonti, L.; Aust, D.; Weitz, J.; Distler, M.; Solimena, M.
10.1101/2024.05.25.595863 — molecular biology — Posted on 2024-05-25
849 Single-cell transcriptomics reveal synergistic and antagonistic effects of T21 and GATA1s on hematopoiesis
Takasaki, K.; Wafula, E. K.; Kumar, S. S.; Smith, D.; Gagne, A. L.; French, D. L.; Thom, C. S.; Chou, S. T.
10.1101/2024.05.24.595827 — molecular biology — Posted on 2024-05-25
850 Skeletal muscle myosin heavy chain protein fragmentation as a potential marker of protein degradation in response to resistance training and disuse atrophy
Plotkin, D. L.; Mattingly, M. L.; Anglin, D. A.; Michel, J. M.; Godwin, J. S.; McIntosh, M. C.; Bergamasco, J. G. A.; Scarpelli, M. C.; Angleri, V.; Taylor, L. W.; Willoughby, D. S.; Mobley, C. B.; Kavazis, A. N.; Ugrinowitsch, C.; Libardi, C. A.; Roberts, M. D.
10.1101/2024.05.24.595789 — molecular biology — Posted on 2024-05-25
851 Antifungal potency of terbinafine as a therapeutic agent against Exophiala dermatitidis in vitro
Nakamura, T.; Yoshinouchi, T.; Okumura, M.; Yokoyama, T.; Mori, D.; Nakata, H.; Yasunaga, J.-i.; Tanaka, Y.
10.1101/2024.05.25.595862 — microbiology — Posted on 2024-05-25
853 Polyomavirus ALTOs, but not MTs, downregulate viral early gene expression by activating the NF-κB pathway
Salisbury, N. J. H.; Amonkar, S.; Landazuri Vinueza, J.; Carter, J. J.; Roman, A.; Galloway, D. A.
10.1101/2024.05.24.595774 — microbiology — Posted on 2024-05-25
856 Microbial species exist and are maintained by ecological cohesiveness coupled to high homologous recombination.
Conrad, R. E.; Brink, C. E.; Viver, T.; Rodriguez-R, L. M.; Aldeguer Riquelme, B.; Hatt, J.; Venter, S. N.; Amann, R.; Rossello-Mora, R.; Konstantinidis, K. T.
10.1101/2024.05.25.595874 — microbiology — Posted on 2024-05-25
859 Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease
VanPortfliet, J. J.; Lei, Y.; Martinez, C. G.; Wong, J.; Pflug, K.; Sitcheran, R.; Kneeland, S. C.; Murray, S. A.; McGuire, P. J.; Cannon, C. L.; West, A. P.
10.1101/2024.05.11.593693 — immunology — Posted on 2024-05-25
860 Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
Tavakoli, N.; Fong, E. J.; Coleman, A.; Huang, Y.-K.; Bigger, M.; Doche, M. E.; Kim, S.; Lenz, H.-J.; Graham, N. A.; Macklin, P.; Finley, S. D.; Mumenthaler, S. A.
10.1101/2024.05.24.595756 — systems biology — Posted on 2024-05-25
861 Spatial Modeling Algorithms for Reactions and Transport (SMART) in Biological Cells
Francis, E. A.; Laughlin, J. G.; Dokken, J. S.; Finsberg, H. N. T.; Lee, C. T.; Rognes, M. E.; Rangamani, P.
10.1101/2024.05.23.595604 — systems biology — Posted on 2024-05-25
862 Efficient and multiplexed somatic genome editing with Cas12a mice
Hebert, J. D.; Xu, H.; Tang, Y. J.; Ruiz, P. A.; Detrick, C. R.; Wang, J.; Hughes, N. W.; Donosa, O.; Andrejka, L.; Karmakar, S.; Aboiralor, I.; Tang, R.; Sage, J.; Cong, L.; Petrov, D.; Winslow, M. M.
10.1101/2024.03.07.583774 — cancer biology — Posted on 2024-05-25
863 GAGA zinc finger transcription factor searches chromatin by 1D-3D facilitated diffusion
Feng, X. A.; Yamadi, M.; Fu, Y.; Ness, K. M.; Liu, C.; Ahmed, I.; Bowman, G. D.; Johnson, M. E.; Ha, T.; Wu, C.
10.1101/2023.07.14.549009 — biophysics — Posted on 2024-05-25
870 Multimodal gradients of basal forebrain connectivity across the neocortex
Chakraborty, S.; Haast, R. A.; Onuska, K. M.; Kanel, P.; Prado, M. A. M.; Prado, V.; Khan, A. R.; Schmitz, T. W.
10.1101/2023.05.26.541324 — neuroscience — Posted on 2024-05-25
871 Proteomic analysis to classify extracellular vesicles and plasmodesmata in Arabidopsis cell culture supernatants
Takei, T.; Asou, T.; Hamakawa, N.; Noguchi, R.; Sumiyoshi, K.; Sueyoshi, K.; Imami, K.; Hamada, T.
10.1101/2024.05.17.594688 — plant biology — Posted on 2024-05-25
873 Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer
Kim, W.; Mirdita, M.; Karin, E. L.; Gilchrist, C. L. M.; Schweke, H.; Soeding, J.; Levy, E.; Steinegger, M.
10.1101/2024.04.14.589414 — bioinformatics — Posted on 2024-05-25
874 A chromosome-level genome assembly of the cabbage aphid Brevicoryne brassicae
Wu, J.; Li, G.; Lin, Z.; Zhang, Y.; Yu, W.; Hu, R.; Zhan, S.; Chen, Y.
10.1101/2024.05.16.594461 — genomics — Posted on 2024-05-25
875 Gene drive-based population suppression in the malaria vector Anopheles stephensi
Xu, X.; Chen, J.; Wang, Y.; Liu, Y.; Zhang, Y.; Jia, X.; Yang, J.; Yang, X.; He, Z.; Champer, J.
10.1101/2024.05.24.595689 — genetics — Posted on 2024-05-25
877 The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease
Barzegar Behrooz, A.; Aghanoori, M.-R.; Khodagholi, F.; Nazari, M.; Latifi Navid, H.; Vosoghian, F.; Anjomani, M.; Lotfi, J.; Ahmadiani, A.; Eliassi, A.; Nabavizadeh, F.; Soleimani, E.; Ghavami, S.; Fahanik Babaei, J.
10.1101/2024.05.12.593775 — cell biology — Posted on 2024-05-25
882 Protein N-Terminomics Reveals Major Proteases in Regulating Beige Adipocyte Differentiation
Chang, H.-Y.; Chang, C.-H.; Nishida, H.; Takamuro, K.; Ogata, K.; Peng, K.-C.; Lin, L.-C.; Lo, Y.-J.; Huang, T.-C.; Ishihama, Y.
10.1101/2022.07.31.502230 — cell biology — Posted on 2024-05-25
886 Sex-focused analyses of M83 A53T hemizygous mouse model with recombinant human alpha-synuclein preformed fibril injection identifies female resilience to disease progression: A combined magnetic resonance imaging and behavioural study.
Tullo, S.; Park, J.; Gallino, D.; Park, M.; Mar, K.; Novikov, V.; Sandoval Contreras, R.; Patel, R.; del Cid-Pellitero, E.; Fon, E. A.; Luo, W.; Shlaifer, I.; Durcan, T. M.; Prado, M. A. M.; Prado, V. F.; Devenyi, G. A.; Chakravarty, M. M.
10.1101/2024.05.24.595642 — neuroscience — Posted on 2024-05-25
888 A reference-free algorithm discovers regulation in the plant transcriptome
Meyer, E.; Saldivar, E.; Kokot, M.; Xue, B.; Deorowicz, S.; Rhee, S. Y.; Salzman, J.
10.1101/2024.05.23.595613 — bioinformatics — Posted on 2024-05-25
892 Oriented nucleosome binding by the pioneer factor ELF2
Xiao, T.; Crowe-McAuliffe, C.; Ochmann, M.; Zhu, F.; Osmala, M.; Rogerson, C.; Cramer, P.; Dienemann, C.; Taipale, J.
10.1101/2024.05.24.595749 — biochemistry — Posted on 2024-05-25
893 Structural basis of promiscuous inhibition of Listeria virulence activator PrfA by oligopeptides
Hainzl, T.; Scortti, M.; Lindgren, C.; Grundstrom, C.; Krypotou, E.; Vazquez-Boland, J. A.; Sauer-Eriksson, A. E.
10.1101/2024.05.24.595734 — biochemistry — Posted on 2024-05-25
894 An acidic loop in the FHA domain of the yeast meiosis-specific kinase Mek1 interacts with a specific motif in a subset of Mek1 substrates
Weng, Q.; Wan, L.; Straker, G. C.; Deegan, T. D.; Duncker, B. P.; Neiman, A. M.; Luk, E.; Hollingsworth, N. M.
10.1101/2024.05.24.595751 — genetics — Posted on 2024-05-25
896 Enhanced endogenous gene tagging in human induced pluripotent stem cells via AAV6-mediated donor delivery
Ehlers, E. A.; Klein, K. N.; Fuqua, M. A.; Torvi, J. R.; Chavez, J.; Kuo, L. M.; McCarley, J.; Smith, J. E.; Turman, G.; Yi, D.; Gunawardane, R. N.; Roberts, B.
10.1101/2024.05.24.595765 — cell biology — Posted on 2024-05-25
897 A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release
Elsharkasy, O. M.; Hegeman, C. V.; Lansweers, I.; Cotugno, O. L.; de Groot, I. Y.; de Wit, Z. E. N. M. J.; Liang, X.; Garcia-Guerra, A.; Moorman, N. J. A.; Lefferts, J.; de Voogt, W. S.; Gitz-Francois, J. J.; van Wesel, A. C. W.; El Andaloussi, S.; Schiffelers, R. M.; Kooijmans, S. A. A.; Mastrobattista, E.; Vader, P.; de Jong, O. G.
10.1101/2024.05.24.595612 — molecular biology — Posted on 2024-05-24
898 Mammalian RNAi represses pericentromeric lncRNAs to maintain genome stability
Sandoval, R.; Dilsavor, C. N.; Grishanina, N. R.; Patel, V.; Zamudio, J. R.
10.1101/2024.05.09.593425 — molecular biology — Posted on 2024-05-24
902 Tracking Microcystis viruses and infection dynamics across distinct phases of a Microcystis-dominated bloom
Wing, A.; Hegarty, B. E.; Bastien, E.; Denef, V. J.; Evans, J. T.; Dick, G. J.; Duhaime, M. B.
10.1101/2024.05.24.595742 — microbiology — Posted on 2024-05-24
907 Shaping chemodiversity: A unique spirochete symbiont of pyrroloiminoquinone-producing marine sponges
Waterworth, S. C.; Solomons, G. M.; Kalinski, J.-C. J.; Madonsela, L. S.; Parker-Nance, S.; Dorrington, R. A.
10.1101/2024.05.23.595633 — microbiology — Posted on 2024-05-24
911 Advancements in Human Norovirus Cultivation in Human Intestinal Enteroids
Ettayebi, K.; Kaur, G.; Patil, K.; Dave, J.; Ayyar, B. V.; Tenge, V. R.; Neil, F. H.; Zeng, X.-L.; Speer, A. L.; Dirienzi, S.; Britton, R. A.; Blutt, S.; Crawford, S. E.; Ramani, S.; Atmar, R. L.; Estes, M. K.
10.1101/2024.05.24.595764 — microbiology — Posted on 2024-05-24
914 A safe insect-based Chikungunya fever vaccine affords rapid and durable protection in cynomolgus macaques
Adam, A.; Woolsey, C.; Lu, H.; Plante, K. S.; Wallace, S. M.; Rodriguez, L.; Shinde, D. P.; Cui, Y.; Franz, A. W. E.; Thangamani, S.; Comer, J. E.; Weaver, S. C.; Wang, T.
10.1101/2024.05.21.595029 — microbiology — Posted on 2024-05-25
917 Generation length of the world's amphibians and reptiles
Mancini, G.; Santini, L.; Cazalis, V.; Ficetola, G. F.; Meiri, S.; Roll, U.; Silvestri, S.; Pincheira-Donoso, D.; Di Marco, M.
10.1101/2024.05.23.595540 — zoology — Posted on 2024-05-24
918 Molecular phylogenetics of the superfamily Stromboidea (Caenogastropoda): new insights from increased taxon sampling
Irwin, A. R.; Bouchet, P.; Crame, A.; Harper, E. M.; Kronenberg, G. C.; Strong, E. E.; Williams, S. T.
10.1101/2024.05.23.595472 — zoology — Posted on 2024-05-24
923 Establishing remote communication between human operator and engineered intestinal microbe via bio-electronic optical language
Zhang, X.; Feng, Z.; Li, L.; Yang, H.; Dai, P.; Yang, C.; Sun, D.; Li, H.; Wang, H.; Xue, H.; Wang, Y.; Liu, X.; Li, M.; Lu, S.; Ma, X.; Liu, J.; Shi, Y.; Du, T.; Liu, D.; Wang, H.
10.1101/2024.05.24.595785 — synthetic biology — Posted on 2024-05-24
925 Luminescent ingestible electronic capsules for in vivo regulation of optogenetic engineered bacteria
Li, L.; Feng, Z.; Zhang, X.; Li, M.; Yang, H.; Sun, D.; Li, H.; Xue, H.; Wang, H.; Wang, Y.; Liu, L.; Shi, Y.; Liu, D.; Du, T.; Wang, H.
10.1101/2024.05.24.595681 — synthetic biology — Posted on 2024-05-24
927 Mucociliary Clearance is Impaired in Small Airways of Cystic Fibrosis Pigs
Stewart, C. G.; Hilkin, B. M.; Gansemer, N. D.; Dick, D. W.; Sunderland, J. J.; Stoltz, D. A.; Abou Alaiwa, M. H.; Zabner, J.
10.1101/2024.05.22.595427 — physiology — Posted on 2024-05-25
929 Early-life glucocorticoids accelerate lymphocyte count senescence in roe deer
Lalande, L. D.; Bourgoin, G.; Carbillet, J.; Cheynel, L.; Debias, F.; Ferte, H.; Gaillard, J.-M.; Garcia, R.; Lemaitre, J.-F.; Palme, R.; Pellerin, M.; Peroz, C.; Rey, B. D.; Vuarin, P.; Gilot-Fromont, E.
10.1101/2024.05.24.595732 — physiology — Posted on 2024-05-25
930 Nuclear eNOS interacts with and S-nitrosates ADAR1 to modulate type I interferon signaling and endothelial function.
Zhou, X.; Kuenne, C.; Guenther, S.; Wittig, I.; Güven, B.; Boutguetait, D.; Delgado Lagos, F.; Sachs, N.; Maegdefessel, L.; Münch, C.; Offermanns, S.; Fleming, I.; Siragusa, M.
10.1101/2024.05.24.595750 — physiology — Posted on 2024-05-25
932 Applying nutritional ecology to optimize diets of crickets raised for food and feed
Muzzatti, M. J.; Harrison, S. J.; McColville, E. R.; Brittain, C. T.; Brzezinski, H.; Manivannan, S.; Stabile, C. C.; MacMillan, H. A.; Bertram, S. M.
10.1101/2024.05.23.595553 — ecology — Posted on 2024-05-25
933 Dietary resilience of coral reef fishes to habitat degradation
Clever, F.; Preziosi, R. F.; Nguyen, B.; De Gracia, B.; Quintero, H.; McMillan, W. O.; Altieri, A. H.; O'Dea, A.; Knowlton, N.; Leray, M.
10.1101/2024.05.22.595166 — ecology — Posted on 2024-05-25
934 Thermoregulation and Diurnal Roost Selection of Boreal Bats During Pre-Hibernation Period
Suominen, K. M.; Fritzen, N. R.; Fjelldal, M. A.; Blomberg, A. S.; Viljamaa, M. J. K.; Lilley, T.
10.1101/2024.05.22.595441 — ecology — Posted on 2024-05-25
936 Stand Age and Climate Change Effects on Carbon Increments and Stock Dynamics
Vangi, E.; Dalmonech, D.; Morichetti, M.; GRIECO, E.; Giannetti, F.; D'Amico, G.; Chirici, G.; Collalti, A.
10.1101/2024.05.23.595487 — ecology — Posted on 2024-05-25
937 Comparative analysis of tardigrade locomotion across life stage, species, and pharmacological treatment
Anderson, E. M.; Houck, S. G.; Conklin, C. L.; Tucci, K. L.; Rodas, J. D.; Mori, K. E.; Armstrong, L. J.; Illingworth, V. B.; Lo, T.-W.; Woods, I. G.
10.1101/2024.05.24.595396 — animal behavior and cognition — Posted on 2024-05-25
938 N-Methyl-D-aspartate receptor hypofunction causes recurrent and transient failures of perceptual inference
Weilnhammer, V.; Rothkirch, M.; Yilmaz, D.; Fritsch, M.; Ptasczynski, L. E.; Reichenbach, K.; Roediger, L.; Corlett, P.; Sterzer, P.
10.1101/2024.05.24.595590 — neuroscience — Posted on 2024-05-24
944 Functional Heterogeneity of Voice-Encoding Cortex Revealed by Clinical Language Mapping
Harford, E. E.; Rupp, K. M.; Welch, W. P.; Al-Ramadhani, R.; Ghuman, A.; Holt, L. L.; Abel, T. J.
10.1101/2024.05.24.595794 — neuroscience — Posted on 2024-05-24
945 A glycolytic metabolite restores DNA repair and ameliorates neuropathology in Huntington's disease
CHAKRABORTY, A.; Sreenivasmurthy, S. G.; Miller, W.; Huai, W.; Biswas, T.; Mandal, S. M.; Bosca, L.; Krishnan, B.; Ghosh, G.; Hazra, T.
10.1101/2023.10.26.564220 — biochemistry — Posted on 2024-05-24
948 Investigating Subpopulation Dynamics in Clonal CHO-K1 Cells with Single-Cell RNA Sequencing
Morina, L. B.; Cao, H. C.; Chen, A.; Kumar, S.; McFarland, K. S.; Majewska, N. I.; Betenbaugh, M.; Timp, W.
10.1101/2024.05.22.595338 — genomics — Posted on 2024-05-24
950 Natural variation in yeast reveals multiple paths for acquiring higher stress resistance
Scholes, A. N.; Stuecker, T. N.; Hood, S. E.; Locke, C. J.; Stacy, C. L.; Zhang, Q.; Lewis, J. A.
10.1101/2023.11.20.567940 — genomics — Posted on 2024-05-24
951 Gene drive-based population suppression in the malaria vector Anopheles stephensi
Xu, X.; Chen, J.; Wang, Y.; Liu, Y.; Zhang, Y.; Jia, X.; Yang, X.; He, Z.; Champer, J.
10.1101/2024.05.24.595689 — genetics — Posted on 2024-05-24
952 ADR-2 regulates fertility and oocyte fate in C. elegans
Erdmann, E. A.; Forbes, M.; Becker, M.; Perez, S.; Hundley, H. A.
10.1101/2023.11.01.565157 — genetics — Posted on 2024-05-24
957 Recent evolution of large offspring size and post-fertilization nutrient provisioning in swordtails
Payne, C. Y.; Ly, D.; Rodriguez-Soto, R. A.; Powell, D. L.; Robles, N. D.; Gunn, T. R.; Baczenas, J. J.; Bergman, A. J.; Pollock, A. C.; Moran, B. M.; Baker, J. C.; Reznick, D.; Schumer, M.
10.1101/2023.12.15.571831 — evolutionary biology — Posted on 2024-05-25
959 Clonal evolution of hematopoietic stem cells after cancer chemotherapy
Uryu, H.; Saeki, K.; Haeno, H.; Kapadia, C. D.; Furudate, K.; Nangalia, J.; Chapman, M. S.; Zhao, L.; Hsu, J. I.; Zhao, C.; Chen, S.; Tanaka, T.; Li, Z.; Yang, H.; DiNardo, C.; Daver, N.; Pemmaraju, N.; Jain, N.; Ravandi, F.; Zhang, J.; Song, X.; Thompson, E.; Tang, H.; Little, L.; Gumbs, C.; Orlowski, R.; Qazilbash, M.; Bhalla, K.; Colla, S.; Kantarjian, H.; Shamanna, R. K.; Bueso-Ramos, C.; Nakada, D.; Futreal, P. A.; Shpall, E.; Goodell, M.; Garcia-Manero, G.; Takahashi, K.
10.1101/2024.05.23.595594 — cancer biology — Posted on 2024-05-24
960 Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies
He, T.; Xiao, L.; Qiao, Y.; Klingbeil, O.; Young, E.; Wu, X. S.; Mannan, R.; Mahapatra, S.; Eyunni, S.; Tien, J. C.-Y.; Wang, X.; Zheng, Y.; Kim, N.; Zheng, H.; Hou, S.; Su, F.; Miner, S. J.; Mehra, R.; Cao, X.; Abbineni, C.; Samajdar, S.; Ramachandra, M.; Parolia, A.; Vakoc, C. R.; Chinnaiyan, A. M.
10.1101/2024.01.22.576669 — cancer biology — Posted on 2024-05-24
961 Pelops: A dedicated caller for DUX4 rearrangements from whole-genome sequencing data
Grobecker, P.; Berri, S.; Peden, J. F.; Chow, K.-J.; Fielding, C.; Armogida, I.; Northen, H.; McBride, D. J.; Campbell, P. J.; Becq, J.; Ryan, S. L.; Bentley, D. R.; Harrison, C. J.; Moorman, A. V.; Ross, M. T.; Mijuskovic, M.
10.1101/2024.05.23.595509 — bioinformatics — Posted on 2024-05-24
966 A Near Infrared Fluorescent Nanosensor for Spatial and Dynamic Measurements of Auxin, Indole-3-Acetic Acid, in Planta
Khong, D. T.; Vu, K. V.; Sng, B. J. R.; Choi, I. K. Y.; Porter, T. K.; Cui, J.; Gong, X.; Wang, S.; Nguyen, N. H.; Ang, M.; Park, M.; Lew, T. T. S.; Loh, S. I.; Ahsim, R.; Chin, H. J.; Singh, G. P.; Chan-Park, M. B.; Chua, N.-H.; Strano, M. S.; Jang, I.-C.
10.1101/2024.05.23.595494 — bioengineering — Posted on 2024-05-24
967 FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices
Rosenstein, A.; Sambathkumar, R.; Murareanu, B.; Dhaliwal, N.; Sun, F.; Zhao, X.; Dadvar, A.; Al-attar, R.; Chai, A.; Gulati, N.; Yin, T.; Nguyen, M.; Serra, D.; Devina, T.; Gilbert, P. M.; Kunath, T.; Laflamme, M.; Ogawa, S.; Muffat, J.; Li, Y.; Protze, S.; Nostro, C.; Garton, M. J.
10.1101/2024.05.23.595541 — bioengineering — Posted on 2024-05-24
971 Mechanism of structure-specific DNA binding by the FANCM branchpoint translocase
Abbouche, L.; Murphy, V. J.; Gao, J.; van Twest, S.; Sobinoff, A. P.; Auweiller, K. M.; Pickett, H. A.; Bythell-Douglas, R.; Deans, A. J.
10.1101/2024.05.23.595611 — biochemistry — Posted on 2024-05-24
972 Single-cell proteomics reveals decreased abundance of proteostasis and meiosis proteins in advanced maternal age oocytes
GALATIDOU, S.; PETELSKI, A. A.; PUJOL, A.; LATTES, K.; LATORRACA, L. B.; FAIR, T.; POPOVIC, M.; VASSENA, R.; SLAVOV, N.; BARRAGAN, M.
10.1101/2024.05.23.595547 — cell biology — Posted on 2024-05-24
973 Subtilase SBT5.2 counterbalances flagellin immunogenicity in the plant apoplast
Buscaill, P.; Sanguankiattichai, N.; Kaschani, F.; Huang, J.; Li, Y.; Lyu, J.; Sueldo, D. J.; Kaiser, M.; van der Hoorn, R. A. L.
10.1101/2024.05.23.595557 — plant biology — Posted on 2024-05-24
974 T cells regulate intestinal motility and shape enteric neuronal responses to intestinal microbiota.
Marques de Souza, P. R.; Keenan, C. M.; Wallace, L. E.; Habibyan, Y. B.; Davoli-Ferreira, M.; Ohland, C.; Vicentini, F.; McCoy, K. D.; Sharkey, K. A.
10.1101/2024.05.23.595563 — physiology — Posted on 2024-05-24
975 Genomic factors shaping codon usage across the Saccharomycotina subphylum
Zavala, B.; Dineen, L.; Fisher, K. J.; Opulente, D. A.; Harrison, M.-C.; Wolters, J. F.; Shen, X.-X.; Zhou, X.; Groenewald, M.; Hittinger, C. T.; Rokas, A.; LaBella, A. L.
10.1101/2024.05.23.595506 — genomics — Posted on 2024-05-24
976 A Paradigm For Calling Sequence In Families: The Long Life Family Study
Daw, E. W.; Anema, J. A.; Schwander, K.; Lin, S. J.; Wang, L.; Wojczynski, M.; Thyagarajan, B.; Stitziel, N. O.; Province, M. A.
10.1101/2024.05.23.595584 — genetics — Posted on 2024-05-24
977 The sensory shark: high-quality phenotypic, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates
Mayeur, H.; Leyhr, J.; Mulley, J.; Nicolas, L.; Michel, L.; Sharma, K.; Lagadec, R.; Aury, J.-M.; Osborne, O. G.; Mulhair, P.; Poulain, J.; Mangenot, S.; Mead, D.; Smith, M.; Corton, C.; Oliver, K.; Skelton, J.; Betteridge, E.; Dolucan, J.; Dudchenko, O.; Omer, A.; Weisz, D.; Lieberman-Aiden, E.; McCarthy, S.; Sims, Y.; Torrance, J.; Tracey, A.; Howe, K.; Baril, T.; Hayward, A.; Martinand-Mari, C.; Sanchez, S.; Haitina, T.; Martin, K. J.; MAZAN, S.; Korsching, S. I.; Debiais-Thibaud, M.
10.1101/2024.05.23.595469 — evolutionary biology — Posted on 2024-05-24
979 Hypothalamus-specific NSCs derived from hPSCs ameliorate age-associated dysfunction upon transplantation into aged mouse hypothalamus
Sulistio, Y. A.; Pieknell, K.; Hong, S.; Lee, Y.; Kim, M. S.; Park, W.-Y.; Han, K. Y.; Hong, T.; Park, K.-S.; Yoon, S. G.; Kim, I. Y.; Seong, J. K.; Lee, T. Y.; Kim, M. S.; Lee, S.-H.
10.1101/2024.05.23.595504 — cell biology — Posted on 2024-05-24
980 A sequential, RNA-derived, modified adenosine pathway safeguards cellular metabolism
Ogawa, A.; Watanabe, S.; Kawakami, T.; Tsai, A. Y.-L.; Fuse, J.; Araki, K.; Sawa, S.; Inaba, K.; Wei, F.-Y.
10.1101/2024.05.23.595515 — cell biology — Posted on 2024-05-24
981 Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance
Dadonaite, B.; Ahn, J. J.; Ort, J. T.; Yu, J.; Furey, C.; Dosey, A.; Hannon, W. W.; Baker, A. V.; Webby, R. J.; King, N. P.; Liu, Y.; Hensley, S. E.; Peacock, T. P.; Moncla, L. H.; Bloom, J. D.
10.1101/2024.05.23.595634 — microbiology — Posted on 2024-05-24
985 Antibodies against medically relevant arthropod-borne viruses in the ubiquitous African rodent Mastomy natalensis
De Kesel, W.; Vanden Broecke, B.; Borremans, B.; Fourchault, L.; Willems, E.; Ceulemans, A.; Sabuni, C.; Massawe, A.; Makundi, R. H.; Leirs, H.; Peeters, M.; Verheyen, E.; Gryseels, S.; Marien, J.; Arien, K. K.
10.1101/2024.05.23.595460 — immunology — Posted on 2024-05-24
988 Stomata: Gatekeepers of Uptake and Defense Priming by Green Leaf Volatiles in plants
Maleki, F. A.; Seidl-Adams, I.; Felton, G. W.; Kersch-Becker, M. F.; Tumlinson, J. H.
10.1101/2024.05.22.595386 — ecology — Posted on 2024-05-24
989 Immunogenicity and protective efficacy of an influenza virus-like particle-based SARS-CoV-2 hybrid vaccine candidate in rhesus macaques
Rahman, S. A.; Bommireddy, R.; Routhu, N. K.; Lai, L.; Pack, C. D.; Ramachandiran, S.; Suthar, M. S.; Reddy, S. J. C.; Selvaraj, P.; Amara, R. R.
10.1101/2024.05.24.595657 — immunology — Posted on 2024-05-24
991 Deep Proteome Profiling of Metabolic Dysfunction-Associated Steatotic Liver Disease
Boel, F.; Akimov, V.; Teuchler, M.; Terkelsen, M. K.; Wernberg, C. W.; Larsen, F. T.; Hallenborg, P.; Lauridsen, M. M.; Krag, A.; Mandrup, S.; Ravnskjaer, K.; Blagoev, B.
10.1101/2024.05.24.595658 — systems biology — Posted on 2024-05-24
992 Residues 2-7 of alpha-synuclein regulate amyloid formation via lipid-dependent and -independent pathways
Dewison, K. M.; Rowlinson, B.; Machin, J. M.; Crossley, J. A.; Thacker, D.; Wilkinson, M.; Ulamec, S. E.; Khan, G. N.; Ranson, N. A.; van-Oosten Hawle, P.; Brockwell, D. J.; Radford, S.
10.1101/2024.05.24.595537 — biophysics — Posted on 2024-05-24
993 A cGAMP-containing hydrogel for prolonged SARS-CoV-2 RBD subunit vaccine exposure induces a broad and potent humoral response
Böhnert, V.; Gale, E. C.; Lahey, L. J.; Yan, J.; Powell, A. E.; Ou, B. S.; Carozza, J. A.; Li, L.; Appel, E.
10.1101/2021.07.03.451025 — bioengineering — Posted on 2024-05-24
997 Let-7 restrains an oncogenic epigenetic circuit in alveolar type 2 cells to prevent ectopic formation of fibrogenic AT2 intermediates and pulmonary fibrosis
Seasock, M. J.; Shafiquzzaman, M.; Ruiz-Echartea, M. E.; Kanchi, R. S.; Tran, B. T.; Simon, L. M.; Meyer, M. D.; Erice, P. A.; Lotlikar, S. L.; Wenlock, S. C.; Ochsner, S. A.; Enright, A.; Carisey, A. F.; Romero, F.; Rosas, I. O.; King, K. Y.; McKenna, N. J.; Coarfa, C.; Rodriguez, A.
10.1101/2024.05.22.595205 — cell biology — Posted on 2024-05-24
998 An in vivo 'turning model' reveals new RanBP9 interactions in lung macrophages.
Kajimura, Y.; Tessari, A.; Orlacchio, A.; Thoms, A.; Cufaro, M. C.; Di Marco, F.; Amari, F.; Chen, M.; Soliman, S. S. H.; Rizzotto, L.; Zhang, L.; Amann, J.; Carbone, D. P.; Ahmed, A.; Fiermonte, G.; Freitas, M.; Lodi, A.; Del Boccio, P.; Palmieri, D.; Coppola, V.
10.1101/2024.05.22.595416 — cell biology — Posted on 2024-05-24
999 Metabolic Adaptations in Adult Spiny Mouse (Acomys) Cardiomyocytes Facilitate Enhanced Cardiac Recovery Following Myocardial Infarction
Kuppa, A.; Alzamrooni, A.; Suhan, T.; Chaudhary, R.; Lopez, R.; Collins, N.; Van Den Bergh, F.; Abouleisa, R.; Wang, H.; Mohamed, T.; Satin, J.; Seifert, A. W.; Lyssiotis, C. A.; Beard, D.; Abdel-Latif, A.
10.1101/2024.05.22.595229 — cell biology — Posted on 2024-05-24
1003 Shielding working memory from distraction is more effortful than flexible updating
Papadopetraki, D.; Froboese, M. I.; Westbrook, A. J.; Zandbelt, B. B.; Cools, R.
10.1101/743120 — neuroscience — Posted on 2024-05-24
1005 Adaptive thermogenesis is mediated by GDF15 via the GFRAL neuronal axis in mice
Kim, J. E.; Ju, S.-H.; Lee, M.; Hong, H. J.; Yaseen, U.; Zhang, B.; Lee, S. E.; Kang, Y. E.; Kim, J. T.; Yi, H.-S.; Yi, Y.-S.; Jun, S.; Park, M.; Kim, J.; Auwerx, J.; Sohn, J.-W.; Lee, J. H.; Shong, M.
10.1101/2024.01.15.575796 — molecular biology — Posted on 2024-05-24
1006 Plasmid-driven strategies for clone success in Escherichia coli
Arredondo-Alonso, S.; Pontinen, A. K.; Gama, J.; Gladstone, R. A.; Harms, K.; Tonkin-Hill, G.; Thorpe, H. A.; Simonsen, G. S.; Samuelsen, O.; Johnsen, P. J.; Corander, J.
10.1101/2023.10.14.562336 — microbiology — Posted on 2024-05-24
1007 Development of RT-RPA-based point-of-care tests for epidemic arthritogenic alphaviruses
Sridhar, S.; Tonto, P. B.; Lumkong, L.; Netto, E. M.; Brites, C.; Wang, W.-K.; Herrera, B. B.
10.1101/2024.05.14.594209 — microbiology — Posted on 2024-05-24
1010 Physiological bias governs neutrophil inflammatory threat perception
Pajonczyk, D.; Pauli, L.; Puent, C.; Sternschulte, M. F.; Fehler, O.; Vogl, T.; Soehnlein, O.; Bermudez, M.; Raabe, C. A.; Rescher, U.
10.1101/2024.04.05.588243 — systems biology — Posted on 2024-05-24
1011 ATG8 delipidation is not universally critical for autophagy in plants
Zou, Y.; Ohlsson, J. A.; Holla, S.; Sabljic, I.; Leong, J. X.; Ballhaus, F.; Krebs, M.; Schumacher, K.; Moschou, P. N.; Stael, S.; Uestuen, S.; Dagdas, Y.; Bozhkov, P.; Minina, E. A.
10.1101/2023.08.23.554513 — plant biology — Posted on 2024-05-24
1012 Elephants develop wrinkles through both form and function
Schulz, A. K.; Reveyaz, N.; Kaufmann, L.; Ritter, C.; Hildebrandt, T.; Brecht, M. K.
10.1101/2023.08.24.554618 — physiology — Posted on 2024-05-24
1014 Impact of Phosphorylation on the Structural Ensemble of alpha-Synuclein in Aqueous Solution
Dorn, A. E.; de Bruyn, E.; Rossetti, G.; Fernandez, C.; Outeiro, T. F.; Schulz, J. B.; Carloni, P.
10.1101/2023.03.10.531864 — biophysics — Posted on 2024-05-24
1015 Novel histones and histone variant families in prokaryotes
Schwab, S.; Hu, Y.; van Erp, B.; Cajili, M. K. M.; Hartmann, M. D.; Hernandez Alvarez, B.; Alva, V.; Boyle, A. L.; Dame, R. T.
10.1101/2023.06.01.543357 — bioinformatics — Posted on 2024-05-24
1017 Early prediction of declining health in small ruminants with accelerometers and machine learning
Montout, A. X.; Bhamber, R. S.; Lange, D. S.; Ndlovu, D. Z.; Morgan, E. R.; Ioannou, C. C.; Terrill, T. H.; Van Wyk, J. A.; Burghardt, T.; Dowsey, A. W.
10.1101/2020.08.03.234203 — animal behavior and cognition — Posted on 2024-05-24
1018 Million years old recombination suppression and balancing selection in a region linked to the mating-type locus in the invasive chestnut blight fungal pathogen Cryphonectria parasitica
Hartmann, F. E.; Rodriguez de la Vega, R. C.; Demene, A.; Badet, T.; Vernadet, J.-P.; Rougemont, Q.; Labat, A.; Snirc, A.; Stauber, L.; Croll, D.; Prospero, S.; Dutech, C.; Giraud, T.
10.1101/2024.03.29.587348 — evolutionary biology — Posted on 2024-05-24
1020 Time-Resolved Interactome Profiling Deconvolutes Secretory Protein Quality Control Dynamics
Wright, M. T.; Timalsina, B.; Lopez, V. A. G.; Hermanson, J. N.; Garcia, S.; Plate, L.
10.1101/2022.09.04.506558 — cell biology — Posted on 2024-05-24
1021 Single-cell transcriptional and epigenetic mapping reveals cellular and molecular mechanisms driving non-ischemic cardiac fibrosis
Krstevski, C.; Farrugia, G. E.; Hsu, i.; Dona, M. S. I.; Gaynor, T. L.; Cohen, C. D.; Harper, R. L.; Harrison, T. I.; Claridge, B.; Drack, A.; Lelliott, P.; Kiriazis, H.; Brown, A.; McMullen, J. R.; Donner, D. G.; Lal, S.; Greening, D. W.; Pinto, A. R.
10.1101/2024.05.09.593315 — cell biology — Posted on 2024-05-24
1022 Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
Yan, X.; Kuster, D.; Mohanty, P.; Nijssen, J.; Pombo-Garcia, K.; Rizuan, A.; Franzmann, T. M.; Sergeeva, A.; dos Passos, P. M.; George, L.; Wang, S.-H.; Shenoy, J.; Danielson, H. L.; Honigmann, A.; Ayala, Y. M.; Fawzi, N. L.; Mittal, J.; Alberti, S.; Hyman, A. A.
10.1101/2024.01.23.576837 — cell biology — Posted on 2024-05-24
1023 A microtubule stability switch alters isolated vascular smooth muscle calcium flux in response to matrix rigidity
Johnson, R. T.; Wostear, F.; Solanki, R.; Steward, O.; Morris, C. J.; Bidula, S.; Warren, D. T.
10.1101/2022.11.23.517637 — cell biology — Posted on 2024-05-24
1025 A gene expression program activated by neuronal inactivity
Zhu, Z.; Lennon, J.; Barry, T. M.; Sanchez Ortiz, T.; Lymer, S.; Mezan, S.; Kadener, S.; Blau, J.
10.1101/636878 — neuroscience — Posted on 2024-05-24
1026 SignEEG v1.0 : Multimodal Electroencephalography and Signature Database for Biometric Systems
Mishra, A. R.; Kumar, R.; Gupta, V.; Prabhu, S.; Upadhyay, R.; Chhipa, P. C.; Rakesh, S.; Mokayed, H.; Das Chakladar, D.; De, K.; Liwicki, M.; Liwicki, F. S.; Saini, R.
10.1101/2023.09.09.556960 — neuroscience — Posted on 2024-05-24
1028 Predictive Biophysical Neural Network Modeling of a Compendium of in vivo Transcription Factor DNA Binding Profiles for Escherichia coli
Lally, P.; Gomez-Romero, L.; Tierrafria, V. H.; Aquino, P.; Rioualen, C.; Zhang, X.; Kim, S.; Baniulyte, G.; Plitnick, J.; Smith, C.; Babu, M.; Collado-Vides, J.; Wade, J.; Galagan, J. E.
10.1101/2024.05.23.594371 — bioinformatics — Posted on 2024-05-24
1029 Enhancing affinity of neutralizing SARS-CoV-2 nanobody through facile structure-guided mutations in CDRs
Singh, V.; Bhutkar, M.; Choudhary, S.; Nehul, S.; Kumar, R.; Singla, J.; Kumar, P.; Tomar, S.
10.1101/2024.05.13.593833 — bioengineering — Posted on 2024-05-24
1030 Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines
Clark, T. W.; Mohan, J.; Schaffer, L. V.; Obernier, K.; Al Manir, S.; Churas, C. P.; Dailamy, A.; Doctor, Y.; Forget, A.; Hansen, J. N.; Hu, M.; Levinson, M. A.; Marquez, C.; Nourreddine, S.; Niestroy, J.; Pratt, D.; Qian, G.; Thaker, S.; Belisle-Pipon, J.-C.; Brandt, C.; Chen, J.; Ding, Y.; Fodeh, S.; Krogan, N.; Lundberg, E.; Mali, P.; Payne-Foster, P.; Ratcliffe, S. J.; Ravitsky, V.; Sali, A.; Schulz, W.; Ideker, T.
10.1101/2024.05.21.589311 — systems biology — Posted on 2024-05-24
1031 Domesticated cannabinoid synthases amid a wild mosaic cannabis pangenome
Lynch, R. C.; Padgitt-Cobb, L. K.; Garfinkel, A. R.; Knaus, B. J.; Hartwick, N. T.; Allsing, N.; Aylward, A.; Mamerto, A.; Kitony, J. K.; Colt, K.; Murray, E. R.; Duong, T.; Trippe, A.; Crawford, S.; Vining, K. J.; Michael, T. P.
10.1101/2024.05.21.595196 — plant biology — Posted on 2024-05-24
1032 Microbiota-dependent in vivo biotransformation, accumulation, and excretion of arsenic from arsenobetaine-rich diet
Mukherjee, M.; Brandenburg, L.; Dong, Y.; Pfister, S.; Sidler, A.; Mestrot, A.; Capilla, T. C.; Hapfelmeier, S.
10.1101/2024.05.21.594793 — pharmacology and toxicology — Posted on 2024-05-24
1033 A proteogenomic atlas of the human neural retina
Riepe, T.; Stemerdink, M.; Salz, R.; Duenas Rey, A.; de Bruijn, S. E.; Boonen, E.; Tomkiewicz, T. Z.; Kwint, M.; Gloerich, J.; Wessels, H. J. C. T.; De Baere, E.; van Nieuwerburgh, F.; De Keulenaer, S.; Ferrari, B.; Ferrari, S.; Coppieters, F.; Cremers, F. P. M.; van Wyk, E.; Roosing, S.; de Vrieze, E.; 't Hoen, P. A. C.
10.1101/2024.05.22.595273 — genetics — Posted on 2024-05-24
1035 Red knots in Europe - a dead end host species or a new niche for highly pathogenic avian influenza?
King, J.; Pohlmann, A.; Bange, A.; Horn, E.; Hälterlein, B.; Breithaupt, A.; Globig, A.; Günther, A.; Kelm, A.; Wiedemann, C.; Grund, C.; Haecker, K.; Garthe, S.; Harder, T.; Beer, M.; Schwemmer, P.
10.1101/2024.05.21.593879 — ecology — Posted on 2024-05-24
1036 National-scale acoustic monitoring of avian biodiversity and phenology
Bick, A.; Bakkestuen, V.; Cretois, B.; Hillier, B.; Kalas, J. A.; Pedersen, M.; Raja, K.; Rosten, C.; Somveille, M.; Stokke, B.; Wiel, J.; Sethi, S. S.
10.1101/2024.05.21.595242 — ecology — Posted on 2024-05-24
1039 Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
Bell, T. A.; Luce, B. E.; Hakim, P.; Ananda, V. Y.; Dardari, H.; Nguyen, T. H.; Monshizadeh, A.; Chao, L. H.
10.1101/2023.11.08.566258 — biochemistry — Posted on 2024-05-24
1041 Optimization of the fluorogen-activating protein tag for quantitative protein trafficking and co-localization studies in S. cerevisiae
Oppenheimer, K. G.; Hager, N. A.; McAtee, C. K.; Filiztekin, E.; Shang, C.; Warnick, J. A.; Bruchez, M. P.; Brodsky, J. L.; Prosser, D. C.; Kwiatkowski, A. V.; O'Donnell, A. F.
10.1101/2024.04.20.590399 — cell biology — Posted on 2024-05-24
1042 A Scaffolding Element Rewires Local 3D Chromatin Architecture During Differentiation
Jerkovic, I.; Di Stefano, M.; Reboul, H.; Szalay, M. F.; Normanno, D.; Papadopoulos, G. L.; Bantignies, F.; Cavalli, G.
10.1101/2024.05.23.595561 — cell biology — Posted on 2024-05-24
1046 ERK5 Signaling is Required for Type III IFN-mediated Mucosal Antiviral Responses
Bone, H.; Natour, D. S.; McFadden, M. I.; Karp, A.; Basu, A.; Keller, A.; Denz, P. J.; Collins, P. L.; Mihaylova, M. M.; Yount, J. S.; Forero, A.
10.1101/2024.05.21.595218 — immunology — Posted on 2024-05-24
1050 p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer
Luo, J.; Chen, Z.; Qiao, Y.; Tien, J. C.-Y.; Young, E.; Mannan, R.; Mahapatra, S.; He, T.; Eyunni, S.; Zhang, Y.; Zheng, Y.; Su, F.; Cao, X.; Wang, R.; Cheng, Y.; Seri, R.; George, J.; Shahine, M.; Miner, S. J.; Vaishampayan, U.; Wang, M.; Wang, S.; Parolia, A.; Chinnaiyan, A. M.
10.1101/2024.03.29.587346 — cancer biology — Posted on 2024-05-24
1051 KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation
Anastas, V.; Chavdoula, E.; La Ferlita, A.; Soysal, B.; Cosentini, I.; Nigita, G.; Kearse, M. G.; Tsichlis, P. N.
10.1101/2024.05.22.595403 — cancer biology — Posted on 2024-05-24
1058 Altered striosome-matrix distribution and activity of striatal cholinergic interneurons in a model of autism-linked repetitive behaviors
Molitor, J.; Graniou, J.; Salin, P.; Castets, F.; Fatmi, A.; Kerkerian-Le Goff, L.; Fasano, L.; Caubit, X.; Gubellini, P.
10.1101/2024.05.23.595498 — neuroscience — Posted on 2024-05-23
1060 NMDA receptor activation drives early synapse formation in vivo
Andreae, L. C.; Leibold, N. S.; Higgs, N. F.; Kandler, S.; Khan, A. G.; Donato, F.
10.1101/2024.05.23.595343 — neuroscience — Posted on 2024-05-23
1062 Potassium homeostasis during disease progression of Alzheimers Disease
Samokhina, E.; Mangat, A. K.; Malladi, C. S.; Gyengesi, E.; Morley, J. W.; Buskila, Y.
10.1101/2024.05.23.595252 — neuroscience — Posted on 2024-05-23
1063 A gene expression program activated by neuronal inactivity
Zhu, Z.; Lennon, J.; Barry, T. M.; Sanchez Ortiz, T.; Lymer, S.; Mezan, S.; Kadener, S.; Blau, J.
10.1101/636878 — neuroscience — Posted on 2024-05-24
1064 Intracellular Expression of a Fluorogenic DNA Aptamer Using Retron Eco2
Vibhute, M. A.; Machatzke, C.; Bigler, K.; Krumpel, S.; Summerer, D.; Mutschler, H.
10.1101/2024.05.21.595248 — synthetic biology — Posted on 2024-05-24
1068 A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans
LIN, J.; Miao, J.; Schaefer, K. G.; Russel, C. M.; Pyron, R. J.; Zhang, F.; Phan, Q. T.; Solis-Swidergall, N. V.; Liu, H.; Tashiro, M.; Dordick, J. S.; Linhardt, R. J.; Yeaman, M. R.; King, G. M.; Barrera, F. N.; Peters, B. M.; Filler, S. G.
10.1101/2024.05.23.595417 — microbiology — Posted on 2024-05-23
1069 Sharp transitions in phytoplankton communities across estuarine to open ocean waters of the tropical Pacific
Tucker, S. J.; Rii, Y. M.; Freel, K. C.; Kotubetey, K.; Kawelo, A. H.; Winter, K. B.; Rappe, M. S.
10.1101/2024.05.23.595464 — microbiology — Posted on 2024-05-23
1070 Starve a cold or feed a fever? Identifying cellular metabolic changes following infection and exposure to SARS-CoV-2.
Loveday, E. K.; Welhaven, H. K.; Erdogan, A. E.; Hain, K.; Chang, C. B.; June, R. K.; Taylor, M. P.
10.1101/2024.05.22.595410 — microbiology — Posted on 2024-05-23
1071 Use of Stem Cell-Derived Cardiomyocyte and Nasal Epithelium Models to Establish a Multi-Tissue Model Platform to Validate Repurposed Drugs Against SARS-CoV-2 Infection
Godde, N.; O'Brien, C.; Vincan, E.; Vashi, A.; Olliff, S.; Tran, B.; Waters, S.; Goldie, S.; Jansen van Vuren, P.; Riddell, S.; Bruce, M.; Agarwal, V.; Athan, E.; Blasdell, K. R.; Chahal, S.; Creek, D.; Faheem, F.; Jain, H.; Kirkpatrick, C.; Kumar, A.; MacRaild, C.; Muzaffar-Ur-Rehman, M.; Sankaranarayanan, M.; Shah, R.; Styles, I.; Tachedjian, M.; Trevaskis, N.; Singanallur, N.; McAuley, A.; Vasan, S. S.
10.1101/2024.05.22.595397 — microbiology — Posted on 2024-05-23
1072 Endogenous ZAP affects Zika virus RNA interactome
Sabir, A. J.; Le, N. P. K.; Singh, P. P.; Karniychuk, U.
10.1101/2024.05.23.595534 — microbiology — Posted on 2024-05-23
1076 Molecular phenotypes segregate missense mutations in SLC13A5 Epilepsy
Jaramillo-Martinez, V.; Sennoune, S. R.; Tikhonova, E. B.; Karamyshev, A. L.; Ganapathy, V.; Urbatsch, I.
10.1101/2024.05.23.594637 — biochemistry — Posted on 2024-05-23
1079 Discovery of novel RNA viruses in commercially relevant seaweeds Alaria esculenta and Saccharina latissima
Dekker, R. J.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Cohen, J.; Timmermans, K. R.; Breit, T. M.; Jonker, M. J.
10.1101/2024.05.22.594653 — genomics — Posted on 2024-05-23
1080 Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts
Yuan, D. J.; Zinno, J.; Botella, T.; Dhingra, D.; Wang, S.; Hawkins, A.; Swett, A.; Sotelo, J.; Raviram, R.; Hughes, C.; Potenski, C.; Yokoyama, A.; Kakiuchi, N.; Ogawa, S.; Landau, D. A.
10.1101/2024.05.22.595241 — genomics — Posted on 2024-05-23
1084 Detection of Nontoxic BoNT/A Levels in Post-Facial Botox Injection Breastmilk using a Multi-technique Approach
Gu, H.; Xu, Z.; Koviazina, R.; Tan, P.; Zheng, C.; Kappes, F.; Kotsifaki, D. G.; Shen, F.; Tsigkou, A.
10.1101/2024.05.22.595434 — molecular biology — Posted on 2024-05-23
1086 Microbiomes of three coral species in the Mexican Caribbean and their shifts associated with the Stony Coral Tissue Loss Disease
Arriaga-Pinon, Z. P.; Aguayo-Leyva, J. E.; Alvarez-Filip, L.; Banaszak, A. T.; Aguirre-Macedo, M. L.; Paz-Garcia, D. A.; Garcia-Maldonado, J. Q.
10.1101/2024.05.23.595495 — microbiology — Posted on 2024-05-23
1087 Clostridioides difficile binary toxin CDT induces biofilm-like persisting microcolonies
Torres, J. M.; Tinevez, J.-Y.; Crozouls, A.; Mary, H.; Kim, M.; Hunault, L.; Chamorro-Rodriguez, S.; Lejal, E.; Altamirano-Silva, P.; Gobaa, S.; Peltier, J.; Chassaing, B.; Dupuy, B.
10.1101/2024.05.23.595336 — microbiology — Posted on 2024-05-23
1088 Efficacy of late-onset antiviral treatment in immune-compromised hosts with persistent SARS-CoV-2 infection
Lieber, C. M.; Kang, H.-J.; Sobolik, E. B.; Sticher, Z. M.; Ngo, V. L.; Gewirtz, A. T.; Kolykhalov, A. A.; Natchus, M. G.; Greninger, A. L.; Suthar, M. S.; Plemper, R. K.
10.1101/2024.05.23.595478 — microbiology — Posted on 2024-05-23
1090 Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread
Pahmeier, F.; Monticelli, S. R.; Feng, X.; Hjorth, C. K.; Wang, A.; Kuehne, A. I.; Bakken, R. R.; Batchelor, T. G.; Lee, S. E.; Middlecamp, M.; Stuart, L.; Abelson, D. M.; McLellan, J. S.; Biering, S. B.; Herbert, A. S.; Chandran, K.; Harris, E.
10.1101/2024.05.23.595578 — microbiology — Posted on 2024-05-23
1092 SH3BP2 regulates the organization of the neuromuscular synapses through protein-driven phase separation
Pradhan, B.; Bernadzki, K.; Bandaruk, Y.; Siudzinska, A.; De Cicco, T.; Gawor, M.; Krzemien, J.; Chodaczek, G.; Hashemolhosseini, S.; Proszynski, T. J.
10.1101/2024.05.23.595491 — neuroscience — Posted on 2024-05-23
1093 Rapid SARS-CoV-2 Detection Using High-Sensitivity Thickness Shear Mode Sensors
Saleh, S.; Alkalamouni, H.; Antar, K.; Rahme, J.; Muthuswamy, J.; Karam, P.; Zaraket, H.; Khraiche, M.
10.1101/2024.05.22.594713 — bioengineering — Posted on 2024-05-23
1094 Regulation of dopamine release by tonic activity patterns in the striatal brain slice
Boumhaouad, S.; Makowicz, E. A.; Choi, S.; Bouhaddou, N.; Balla, J.; Taghzouti, K.; Sulzer, D.; Mosharov, E.
10.1101/2024.05.22.595411 — neuroscience — Posted on 2024-05-23
1096 Functional roles of neural aPKCs in mouse brain development and survival
El Ellam, A.; Alberto, E. J.; Mercau, M. E.; Pramio, D. T.; Bhat, K. M.; Philbrick, W. M.; Schechtman, D.; Rothlin, C. V.; Ghosh, S.
10.1101/2024.05.22.595312 — developmental biology — Posted on 2024-05-23
1098 AMH protects the ovary from doxorubicin by regulating cell fate and the response to DNA damage
Nguyen, N. M. P.; Chang, E. M.; Chauvin, M.; Sicher, N.; Kashiwagi, A.; Nagykery, N.; Chow, C.; May, P.; Mermin-Bunnel, A.; Cleverdon, J.; Duong, T.; Meinsohn, M.-C.; Gao, D.; Donahoe, P. K.; Pepin, D.
10.1101/2024.05.23.595356 — developmental biology — Posted on 2024-05-23
1100 Initiation of Lumen Formation from Junctions via Differential Actomyosin Contractility Regulated by Dynamic Recruitment of Rasip1
YIN, J.; Schellinx, N.; Maggi, L.; Gundel, K.; Wiesner, C.; Kotini, M. P.; Lee, M.; Phng, L.-K.; Belting, H. G.; Affolter, M.
10.1101/2024.05.23.595279 — developmental biology — Posted on 2024-05-23
1101 CRISPR-RfxCas13d screening uncovers Bckdk as a post-translational regulator of the maternal-to-zygotic transition in teleosts
Hernandez-Huertas, L.; Moreno-Sanchez, I.; Crespo-Cuadrado, J.; Vargas-Baco, A.; da Silva-Pescador, G.; Santos-Pereira, J. M.; Bazzini, A. A.; Moreno-Mateos, M. A.
10.1101/2024.05.22.595167 — developmental biology — Posted on 2024-05-23
1102 A novel mouse home cage lickometer system reveals sex- and housing-based influences on alcohol drinking
Petersen, N.; Adank, D. N.; Quan, Y.; Edwards, C. M.; Taylor, A.; Winder, D.; Doyle, M. A.
10.1101/2024.05.22.595186 — neuroscience — Posted on 2024-05-23
1104 Potential Benefits of Ketone Therapy as a Novel Immunometabolic Treatment for Schizophrenia
Huizer, K.; Soni, S.; Schmidt, M. A.; Cakici, N.; de Haan, L.; Dyck, J. R. B.; van Beveren, N. J. M.
10.1101/2024.05.23.595523 — neuroscience — Posted on 2024-05-23
1106 Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution
Xiang, R.; Wang, J.; Wang, M.; Chen, Z.; Tao, J.; Ding, R.; Tu, Z.; Wang, S.; Yang, T.; Chen, J.; Jia, Z.; Peng, Q.; Li, X.; Zhang, X.; Chen, S.; Cheng, N.; Zhao, M.; Li, J.; Xue, Q.; Jiang, C.; Pablo, Y. d.; Wilhelmsson, U.; Pekna, M.; Pekny, M.; Mitsios, N.; Liu, C.; Xu, X.; Fan, X.; Mulder, J.; Chen, X.; Liu, L.; Wang, J.
10.1101/2024.05.23.595245 — neuroscience — Posted on 2024-05-23
1111 The individual determinants of morning dream recall
Elce, V.; Bergamo, D.; Bontempi, G.; Pedreschi, B.; Bellesi, M.; Handjaras, G.; Bernardi, G.
10.1101/2024.05.23.595531 — neuroscience — Posted on 2024-05-23
1114 Human neural dynamics of real-world and imagined navigation
Seeber, M.; Stangl, M.; Vallejo, M.; Topalovic, U.; Hiller, S.; Halpern, C. H.; Langevin, J.-P.; Rao, V. R.; Fried, I.; Eliashiv, D.; Suthana, N.
10.1101/2024.05.23.595237 — neuroscience — Posted on 2024-05-23
1117 The Effects of Locus Coeruleus Optogenetic Stimulation on Global Spatiotemporal Patterns in Rats
Anumba, N.; Kelberman, M. A.; Pan, W.; Marriott, A.; Zhang, X.; Xu, N.; Weinshenker, D.; Keilholz, S.
10.1101/2024.05.23.595327 — neuroscience — Posted on 2024-05-23
1122 Top-down and bottom-up interactions rely on nested brain oscillations.
Trajkovic, J.; Veniero, D.; Hanslmayr, S.; Palva, S.; Cruz, G.; Romei, V.; Thut, G.
10.1101/2024.05.23.595462 — neuroscience — Posted on 2024-05-23
1124 Norepinephrine changes behavioral state via astroglial purinergic signaling
Chen, A. B.; Duque, M.; Wang, V. M.; Dhanasekar, M.; Mi, X.; Rymbek, A.; Tocquer, L.; Narayan, S.; Prober, D. A.; Yu, G.; Wyart, C.; Engert, F.; Ahrens, M. B.
10.1101/2024.05.23.595576 — neuroscience — Posted on 2024-05-23
1129 AtVPS13M1 is involved in lipid remodeling in low phosphate and is located at the mitochondria surface in plants
Leterme, S.; Albrieux, C.; Brugiere, S.; Coute, Y.; Dellinger, J.; Gillet, B.; Hughes, S.; Castets, J.; Bernard, A.; Scheuring, D.; Schilling, M.; Jouhet, J.; Michaud, M.
10.1101/2024.05.22.594332 — cell biology — Posted on 2024-05-23
1133 Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19
Golden, T. N.; Mani, S.; Linn, R. L.; Leite, R.; Trigg, N. A.; Wilson, A.; Anton, L.; Mainigi, M.; Conine, C. C.; Kaufman, B. A.; Strauss, J. F.; Parry, S.; Simmons, R. A.
10.1101/2024.02.17.580824 — pathology — Posted on 2024-05-23
1136 KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development
Tinsley, S. L.; Shelley, R. A.; Mall, G. K.; Chianis, E. R. D.; Dhiman, A.; Baral, G.; Kothandaraman, H.; Thoma, M. C.; Daniel, C.; Lanman, N. A.; Pasca di Magliano, M.; Narla, G.; Solorio, L.; Dykhuizen, E.; Sears, R. C.; Allen-Petersen, B.
10.1101/2023.07.01.547283 — cancer biology — Posted on 2024-05-23
1137 MINFLUX Reveals Dynein Stepping in Live Neurons
Schleske, J. M.; Hubrich, J.; Wirth, O.; D'Este, E.; Engelhardt, J.; Hell, S. W.
10.1101/2024.05.22.595351 — biophysics — Posted on 2024-05-23
1138 Decoding glycosylation potential from protein structure across human glycoproteins with a multi-view recurrent neural network
Kellman, B.; Mariethoz, J.; Zhang, Y.; Shaul, S.; Jeffris, M.; Sandoval, D.; Jeffris, M.; Armingol, E.; Bao, B.; Lisacek, F.; Bojar, D.; Lewis, N.
10.1101/2024.05.15.594334 — bioinformatics — Posted on 2024-05-23
1140 Protein structure, a genetic encoding for glycosylation
Kellman, B.; Sandoval, D.; Zaytseva, O.; Brock, K.; Baboo, S.; Nachmanson, D.; Irvine, E.; Armingol, E.; Mih, N.; Zhang, Y.; Jeffris, M.; Bartels, P.; Nguyen, T.; Tam, A.; Gasman, S.; Ilan, S.; Shamie, I.; Diedrich, J.; Wang, X.; van Woudenbergh, E.; Altman, M.; Aylward, A.; Bao, B.; Castro, A.; Sorrentino, J.; Chiang, A.; Campbell, M.; Bartsch, Y.; Aguilar-Calvo, P.; Sigurdson, C.; Alter, G.; Lauc, G.; Yates, J.; Marks, D.; Lisacek, F.; Lewis, N.
10.1101/2024.05.15.594261 — genetics — Posted on 2024-05-23
1141 The balance between intrinsic and ecological fitness defines new regimes in eco-evolutionary population dynamics
Barker-Clarke, R. J.; Gray, J. M.; Strobl, M. A. R.; Tadele, D. S.; Maltas, J.; Hinczewski, M.; Scott, J. G.
10.1101/2023.03.15.532871 — evolutionary biology — Posted on 2024-05-23
1142 Affinity purification mass spectrometry characterization of the interactome of receptor tyrosine kinase proline rich motifs in cancer
Jones, C. M.; Rohwedder, A.; Suen, K. M.; Zahed Mohajerani, S.; Calabrese, A. N.; Knipp, S.; Bedford, M. T.; Ladbury, J. E.
10.1101/2024.05.23.595484 — cell biology — Posted on 2024-05-23
1145 Biomolecular condensates sustain pH gradients at equilibrium driven by charge neutralisation
Ausserwoeger, H.; Scrutton, R. M.; Sneideris, T.; Fischer, C. M.; Qian, D.; de Csillery, E.; Saar, K. L.; Bialek, A. Z.; Oeller, M. M.; Krainer, G.; Franzmann, T. M.; Wittmann, S.; Iglesias-Artola, J. M.; Invernizzi, G.; Hyman, A. A.; Alberti, S.; Lorenzen, N.; Knowles, T. P. J.
10.1101/2024.05.23.595321 — biophysics — Posted on 2024-05-23
1146 Enhanced thermal stability enables human mismatch-specific thymine-DNA glycosylase to catalyse futile DNA repair
Manapkyzy, D.; Joldybayeva, B.; Ishchenko, A.; Matkarimov, B. T.; Zharkov, D. O.; Taipakova, S.; Saparbaev, M.
10.1101/2024.05.21.595234 — biochemistry — Posted on 2024-05-23
1147 Mechanisms of axoneme and centriole elimination in Naegleria gruberi
Gonczy, P.; Woglar, A.; Busso, C.; Garcia-Rodriguez, G.; Douma, F.; Croisier-Coeytaux, M.; Knott, G.
10.1101/2024.05.22.595302 — cell biology — Posted on 2024-05-23
1148 Lipidomics and colistin resistance in non-human isolates of Acinetobacter seifertii
Sykes, E.; Mateo-Estrada, V.; Muzaleva, A.; Zhanel, G.; Dettman, J.; Chapados, J. T.; Gerdis, S.; KHAN, I. U. H.; Castillo-Ramirez, S.; Kumar, A.
10.1101/2024.05.22.595387 — microbiology — Posted on 2024-05-23
1149 Host shapes microevolution of MDR Acinetobacter baumannii during long-term infection
Bednarczuk, L.; Chassard, A.; Plantade, J.; Charpentier, X.; Laaberki, M.-H.
10.1101/2024.05.22.595333 — microbiology — Posted on 2024-05-23
1151 Extracellular vesicles from mucopolysaccharidosis type III microglia impair neurite growth
Dias, C.; Ballout, N.; Morla, G.; Alileche, K.; Santiago, C.; Guerrera, I. C.; Chaubet, A.; Ausseil, J.; Trudel, S.
10.1101/2024.05.22.595318 — neuroscience — Posted on 2024-05-23
1153 Intracellular Expression of a Fluorogenic DNA Aptamer Using Retron Eco2
Vibhute, M. A.; Machatzke, C.; Bigler, K.; Krumpel, S.; Summerer, D.; Mutschler, H.
10.1101/2024.05.21.595248 — synthetic biology — Posted on 2024-05-23
1154 Chemigenetic far-red labels and Ca2+ indicators optimized for photoacoustic imaging.
Cook, A.; Kaydanov, N.; Ugarte-Uribe, B.; Boffi, J. C.; Kamm, G. B.; Prevedel, R.; Deo, C.
10.1101/2024.05.23.595278 — biochemistry — Posted on 2024-05-23
1158 Evaluation of altered cell-cell communication between glia and neurons in the hippocampus of 3xTg-AD mice at two time points
Soelter, T. M.; Howton, T. C.; Wilk, E. J.; Whitlock, J. H.; Clark, A. D.; Birnbaum, A.; Patterson, D. C.; Cortes, C. J.; Lasseigne, B. N.
10.1101/2024.05.21.595199 — genomics — Posted on 2024-05-23
1159 Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants
Hinterding, H.; Baghdadi, M.; Gehrmann, T.; Putter, P.; Neuerburg, M.; Lakenberg, N.; van den Akker, E. B.; Slagboom, P. E.; Deelen, J.; Partridge, L.
10.1101/2023.06.01.541708 — genetics — Posted on 2024-05-23
1162 Autophagy suppression in DNA damaged cells occurs through a newly identified p53-proteasome-LC3 axis
Lieu, D. J.; Crowder, M. K.; Kryza, J. R.; Tamilselvam, B.; Kaminski, P. J.; Kim, I.-J.; Li, Y.; Jeong, E.; Enkhbaatar, M.; Chen, H.; Son, S. B.; Mok, H.; Bradley, K. A.; Phillips, H.; Blanke, S. R.
10.1101/2024.05.21.595139 — cell biology — Posted on 2024-05-23
1163 Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis
Nguyen, H. N.; Jeong, Y.; Kim, Y.; Kim, Y. H.; Athar, H.; Castaldi, P. J.; Hersh, C. P.; Padera, R. F.; Sholl, L. M.; Vivero, M.; Sharma, N. S.; Yun, J.; Merriam, L. T.; Yuan, K.; Kim, E. Y.; Brenner, M. B.
10.1101/2024.05.21.595153 — cell biology — Posted on 2024-05-23
1164 An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression
Siachisumo, C.; Luzzi, S.; Aldalaqan, S.; Hysenaj, G.; Dalgliesh, C.; Cheung, K.; Gazzara, M. R.; Yonchev, I. D.; James, K.; Kheirollahi Chadegani, M.; Ehrmann, I. E.; Smith, G. R.; Cockell, S. J.; Munkley, J.; wilson, s. a.; Barash, Y.; Elliott, D.
10.1101/2023.08.15.553384 — molecular biology — Posted on 2024-05-23
1165 Comparative Analysis of Within-Host Dynamics of Acute Infection and Viral Rebound Dynamics in Postnatally SHIV-Infected ART-Treated Infant Rhesus Macaques
Mainou, E.; Berendam, S.; Obregon-Perko, V.; Uffman, E.; Phan, C.; Shaw, G. M.; Bar, K.; Kumar, M.; Fray, E.; Siliciano, R. F.; Siliciano, J.; Silvestri, G.; Permar, S. R.; Fouda, G.; McCarthy, J.; Chahroudi, A.; Chan, C.; Conway, J. M.
10.1101/2024.05.21.595130 — immunology — Posted on 2024-05-23
1166 Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
Lawrence, L.; Vidal, P.; Varughese, R.; Li, Z.-R.; Chen, T. D.; Tuske, S.; Jimenez, A.; Lowen, A.; Shafer, W.; Kohlmeier, A.
10.1101/2024.05.21.595090 — immunology — Posted on 2024-05-23
1167 Structural characterization and AlphaFold modeling of human T cell receptor recognition of NRAS cancer neoantigens
Wu, D.; Yin, R.; Chen, G.; Ribeiro-Filho, H. V.; Cheung, M.; Robbins, P. F.; Mariuzza, R. A.; Pierce, B. G.
10.1101/2024.05.21.595215 — immunology — Posted on 2024-05-23
1169 Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers
Kuznetsov, M.; Adhikarla, V.; Caserta, E.; Wang, X.; Shively, J.; Pichiorri, F.; Rockne, R. C.
10.1101/2024.05.22.595377 — cancer biology — Posted on 2024-05-23
1170 Loss of p21-activated kinase 4 (PAK4) suppresses pancreatic tumor progression and metastasis through regulating E-cadherin
Kim, K.-J.; Nam, M.; Na, H. Y.; Sung, J. H.; Park, B.-R.; Hwang, S.-H.; Park, W.; Seo, J.; Kang, M.; Jung, E. H.; Kim, S.-A.; Suh, K. J.; Lee, J. Y.; Kim, J.-W.; Kim, S. H.; Lee, J.-O.; Kim, Y. J.; Lee, K.-W.; Kim, J. H.; Bang, S.-M.; Wainberg, Z.; Kim, J. W.
10.1101/2024.05.22.594599 — cancer biology — Posted on 2024-05-23
1171 Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling
Shi, Y.; Wu, Z.; Liu, S.; Zuo, D.; Niu, Y.; Qiu, Y.; Qiao, L.; He, W.; Qiu, J.; Yuan, Y.; Wang, G.; Li, B.
10.1101/2024.05.23.595475 — cancer biology — Posted on 2024-05-23
1174 Repression of pattern-triggered immune responses by hypoxia in Arabidopsis
Mooney, B. C.; Doorly, C. M.; Mantz, M.; Garcia, P.; Huesgen, P. F.; Graciet, E.
10.1101/2023.11.07.565979 — plant biology — Posted on 2024-05-23
1175 Bioengineering secreted proteases converts divergent Rcr3 orthologs and paralogs into extracellular immune co-receptors
Kourelis, J.; Schuster, M.; Demir, F.; Mattinson, O.; Krauter, S.; Kahlon, P. S.; O'Grady, R.; Royston, S.; Bravo-Cazar, A. L.; Mooney, B. C.; Huesgen, P. F.; Kamoun, S.; van der Hoorn, R. A. L.
10.1101/2024.02.14.580413 — plant biology — Posted on 2024-05-23
1177 Heterotrimeric Collagen Helix with High Specificity of Assembly Results in a Rapid Rate of Folding
Cole, C. C.; Walker, D. R.; Hulgan, S. A. H.; Pogostin, B. H.; Swain, J. W. R.; Miller, M. D.; Xu, W.; Duella, R.; Misiura, M.; Wang, X.; Kolomeisky, A.; Phillips, G.; Hartgerink, J. D.
10.1101/2024.05.21.595195 — biophysics — Posted on 2024-05-23
1179 Haspin kinase binds to a nucleosomal DNA supergroove
Hicks, C. W.; Gliech, C. R.; Zhang, X.; Rahman, S.; Vasquez, S.; Holland, A. J.; Wolberger, C.
10.1101/2024.05.21.595243 — biophysics — Posted on 2024-05-23
1180 A deep dive into the FALSIFLORA contribution to tomato reproductive development through a comprehensive allelic series analysis
Quevedo-Colmena, A. S.; Vriezen, W. H.; Wesselink, P. G. A.; Perez, J. M.; Pineda, B.; Garcia-Sogo, B.; Angosto, T.; Moreno, V.; Yuste-Lisbona, F. J.; Lozano, R.
10.1101/2024.05.21.595162 — plant biology — Posted on 2024-05-23
1184 Estimating full-field displacement in biological images using deep learning
Warsop, S. J. E. T.; Caixeiro, S.; Bischoff, M.; Kursawe, J.; Bruce, G. D.; Wijesinghe, P.
10.1101/2024.05.21.595161 — biophysics — Posted on 2024-05-23
1187 TRPV4-Expressing Tissue-Resident Macrophages Regulate the Function of Collecting Lymphatic Vessels via Thromboxane A2 Receptors in Lymphatic Muscle Cells
Schulz, M. E.; Akerstrom, V. L.; Song, K.; Broyhill, S. E.; Li, M.; Lambert, M. D.; Goldberg, T. B.; Kataru, R. P.; Shin, J.; Braun, S. E.; Norton, C. E.; Czepielewski, R. S.; Mehrara, B. J.; Domeier, T. L.; Zawieja, S. D.; Castorena-Gonzalez, J. A.
10.1101/2024.05.21.595189 — physiology — Posted on 2024-05-23
1190 Cellular coordination underpins rapid reversals in gliding filamentous cyanobacteria and its loss results in plectonemes
Rosko, J.; Cremin, K.; Locatelli, E.; Coates, M.; Duxbury, S. J. N.; Randall, K.; Croft, K.; Valeriani, C.; Polin, M.; Soyer, O. S.
10.1101/2024.02.06.579126 — biophysics — Posted on 2024-05-23
1192 Single-cell and spatiotemporal profile of ovulation in the mouse ovary
Huang, R.; Kratka, C. E.; Pea, J.; McCann, C.; Nelson, J.; Bryan, J. P.; Zhou, L. T.; Russo, D. D.; Zaniker, E. J.; Gandhi, A. H.; Shalek, A. K.; Cleary, B.; Farhi, S. L.; Duncan, F. E.; Goods, B. A.
10.1101/2024.05.20.594719 — bioinformatics — Posted on 2024-05-23
1194 Pervasive ancestry bias in variant effect predictors
Pathak, A. K.; Bora, N.; Badonyi, M.; Livesey, B. J.; SG10K_Health Consortium, ; Ngeow, J.; Marsh, J. A.
10.1101/2024.05.20.594987 — bioinformatics — Posted on 2024-05-23
1195 Radiation dermatitis in the hairless mouse model mimics human radiation dermatitis
Lawrence, J.; Seelig, D.; Demos-Davies, K.; Ferreira, C.; Ren, Y.; Wang, L.; Alam, S. K.; Yang, R.; Guedes, A.; Craig, A.; Hoeppner, L. H.
10.1101/2024.05.21.595074 — pathology — Posted on 2024-05-23
1202 Freeform robotic optical coherence tomography beyond the optical field-of-view limit
Fang, R.; Zhang, P.; Zhang, T.; Kim, D.; Sun, E.; Kuranov, R.; Kweon, J.; Huang, A.; Zhang, H. F.
10.1101/2024.05.21.595073 — bioengineering — Posted on 2024-05-23
1203 Enhanced dynamic covalent chemistry for the controlled release of small molecules and biologics from a nanofibrous peptide hydrogel platform
Pogostin, B. H.; Wu, S. X.; Swierczynski, M. J.; Pennington, C.; Li, S.-Y.; Vohidova, D.; Seeley, E. H.; Agrawal, A.; Tang, C.; Cabler, J.; Dey, A.; Veiseh, O.; Nuermberger, E. L.; Ball, Z. T.; Hartgerink, J. D.; McHugh, K. J.
10.1101/2024.05.21.595134 — bioengineering — Posted on 2024-05-23
1204 Automatic segmentation of medial temporal lobe subregions in multi-scanner, multi-modality MRI of variable quality
Li, Y.; Xie, L.; Khandelwal, P.; Wisse, L. E. M.; Brown, C. A.; Prabhakaran, K.; Tisdall, M. D.; Mechanic-Hamilton, D.; Detre, J. A.; Das, S. R.; Wolk, D. A.; Yushkevich, P. A.
10.1101/2024.05.21.595190 — bioengineering — Posted on 2024-05-23
1205 Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach
Merten, E. M.; Sears, J. D.; Leisner, T. M.; Hardy, P. B.; Ghoshal, A.; Hossain, M. A.; Asressu, K. H.; Brown, P. J.; Stashko, M. A.; Herring, L. E.; Mordant, A. L.; Webb, T. S.; Mills, C. A.; Barker, N. K.; Arnold, J. J.; Cameron, C. E.; Streblow, D. N.; Perveen, S.; Arrowsmith, C.; Moorman, N. J.; Heise, M.; Willson, T. M.; Popov, K. I.; Pearce, K. H.
10.1101/2024.03.22.586341 — biochemistry — Posted on 2024-05-23
1206 Genetic excision of the regulatory cardiac troponin I extension in high heart rate mammal clades
Joyce, W.; He, K.; Zhang, M.; Ogunsola, S.; Wu, X.; Joseph, K. T.; Bogomolny, D.; Yu, W.; Springer, M. S.; Xie, J.; Signore, A.; Campbell, K. L.
10.1101/2023.05.19.541292 — evolutionary biology — Posted on 2024-05-23
1207 How fast are viruses spreading in the wild?
Dellicour, S.; Bastide, P.; Rocu, P.; Fargette, D.; Hardy, O. J.; Suchard, M. A.; Guindon, S.; Lemey, P.
10.1101/2024.04.10.588821 — evolutionary biology — Posted on 2024-05-23
1210 Genetic diversity affects ecosystem functions across trophic levels as much as species diversity, but in an opposite direction
Fargeot, L.; Poesy, C.; Lefort, M.; Prunier, J. G.; Krick, M.; Verdonck, R.; Veyssiere, C.; Richard, M.; Legrand, D.; Loot, G.; Blanchet, S.
10.1101/2024.03.27.586944 — ecology — Posted on 2024-05-23
1212 Coral reef potential connectivity in the southwest Indian Ocean
Vogt-Vincent, N. S.; Burt, A. J.; van der Ven, R. M.; Johnson, H. L.
10.1101/2023.11.23.568484 — ecology — Posted on 2024-05-23
1216 Assisted colonisation prospects for the black-veined white butterfly in England
Thomas, C. D.; Cunningham, C. A.; Hulme, N. A. C.; Corrigan, E. C.; Metherell, B.; Green, P.; Oates, M.
10.1101/2024.05.21.595182 — ecology — Posted on 2024-05-23
1220 Formation of vimentin biomolecular condensate-like structures under oxidative stress
Martinez-Cenalmor, P.; Martinez, A. E.; Moneo-Corcuera, D.; Gonzalez-Jimenez, P.; Perez-Sala, D.
10.1101/2024.05.22.595408 — cell biology — Posted on 2024-05-23
1224 Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis.
Wareing, N.; Mills, T. W.; Collum, S.; Wu, M.; Revercomb, L.; Girard, R.; Lyons, M.; Skaug, B.; Bi, W.; Ali, M. A.; Koochak, H.; Flores, A. R.; Yang, Y.; Zheng, W. J.; Swindell, W.; Assassi, S.; Karmouty-Quintana, H.
10.1101/2024.05.22.595271 — molecular biology — Posted on 2024-05-22
1227 Massively parallel screening of TIR-derived peptides reveals vast TLR-targeting immunomodulatory peptides
Lim, Y.; Kang, T. K.; Kim, M. I.; Kim, D.; Kim, J.-Y.; Jung, S. H.; Park, K.; Lee, W.-B.; Seo, M.-H.
10.1101/2024.05.21.595261 — molecular biology — Posted on 2024-05-22
1230 TelAP2 links TelAP1 to the telomere complex in Trypanosoma brucei
Weisert, N.; Majewski, V.; Hartleb, L.; Luko, K.; Lototska, L.; Krapoth, N.; Ulrich, H. D.; Janzen, C. J.; Butter, F.
10.1101/2024.05.22.595291 — microbiology — Posted on 2024-05-22
1231 Short-Term Evolution and Dispersal Patterns of fluconazole-resistance in Candida auris clade III
Cancino-Munoz, I.; Mulet-Bayona, J. V.; Salvador-Garcia, C.; Tormo-Palop, N.; Guna, R.; Gimeno, C.; Gonzalez-Candelas, F.
10.1101/2024.05.22.595305 — microbiology — Posted on 2024-05-22
1236 Characterizing interactions of ER resident proteins in situ through the YST-PPI method
Fan, X.; He, H.; Wang, T.; Xu, P.; Zhang, F.; Hu, S.; Yun, Y.; Mei, M.; Zhang, G.; Yi, L.
10.1101/2024.05.21.594841 — microbiology — Posted on 2024-05-22
1239 Coupled phylogenetic and functional enrichment in the tomato rhizosphere microbiome
Talavera-Marcos, S.; Gallego, R.; Chaboy, R.; Rastrojo, A.; Aguirre de Carcer, D.
10.1101/2024.05.22.595324 — microbiology — Posted on 2024-05-22
1241 Acarbose Impairs Gut Bacteroides Growth by Targeting Intracellular GH97 Enzymes
Koropatkin, N. M.; Brown, H. A.; Morris, A. L.; Pudlo, N. A.; Hopkins, A. E.; Martens, E.; Golob, J. L.
10.1101/2024.05.20.595031 — microbiology — Posted on 2024-05-23
1243 Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice
Aubert, N.; Purcarea, M.; Novarino, J.; Schopp, J.; Audibert, A.; Li, W.; Fornier, M.; Cagnet, L.; Naturel, M.; Casrouge, A.; Blanchard, N.; Dieu-Nosjean, M.-C.; Dietrich, G.; Peirs, C.; Marodon, G.
10.1101/2023.09.12.557326 — immunology — Posted on 2024-05-23
1244 Ultra-low-field paediatric MRI in low- and middle-income countries: super-resolution using a multi-orientation U-Net
Baljer, L.; Zhang, Y.; Bourke, N. J.; Donald, K. A.; Bradford, L. E.; Ringshaw, J. E.; Williams, S. R.; Deoni, S. C.; Williams, S. C.; Khula SA Study Team, ; Vasa, F.; Moran, R. J.
10.1101/2024.02.16.580639 — neuroscience — Posted on 2024-05-23
1247 Unilateral ephaptic program underlying sweetness dominance
Lee, M.; Kim, S. Y.; Park, T.; Joo, K. M.; Kwon, J. Y.; Kim, K.; Kang, K.
10.1101/2023.08.04.551918 — neuroscience — Posted on 2024-05-23
1249 Ellagic acid: a potential inhibitor of enhancer of zeste homolog-2 and protein arginine methyltransferase-5
Nalla, K.; Chatterjee, B.; Poyya, J.; Swain, A.; Ghosh, K.; Pan, A.; Joshi, C. G.; Manavathi, B.; Kanade, S. R.
10.1101/2024.05.22.595443 — cancer biology — Posted on 2024-05-23
1251 Green Jackfruit Flour Prevents Metabolic Dysfunction-Associated Steatohepatitis and Progression to Hepatocellular Carcinoma via the AMPK and MAPK Signaling Pathways
Suresh, D.; Gunaseelan, B.; N. Srinivas, A.; Bharadwaj S A, A.; Joseph, J.; Megha, M.; Varghese, T.; Satish, S.; Suvarna, D.; Santhekadur, P. K.; Chidambaram, S. B.; Duseja, A.; Kumar, D. P.
10.1101/2024.05.23.595466 — cancer biology — Posted on 2024-05-23
1253 Super-Enhancer Driven ZFP36L1 Promotes PD-L1 Expression in Infiltrative Gastric Cancer
Wei, X.; Liu, J.; Zhuo, H.; Cheng, J.; Cai, W.; Xie, W.; Wang, K.; Lin, L.; Hou, J.; Cai, J.
10.1101/2024.05.22.595316 — cancer biology — Posted on 2024-05-23
1254 Spatial Profiling of Metals through Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
Stopka, S.; Bodineau, C.; Baquer, G.; Lin, J.-R.; Hossain, M. A.; Regan, M. S.; Ruiz, D. F.; Fletcher, S.-M.; Pourquie, O.; Lutsenko, S.; Payne, C.; Agar, J. N.; Mazitschek, R.; McDannold, N.; Sorger, P. K.; Santagata, S.; Agar, N.
10.1101/2024.05.22.594980 — cancer biology — Posted on 2024-05-23
1255 KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation
Anastas, V.; Chavdoula, E.; La Ferlita, A.; Soysal, B.; Cosentini, I.; Nigita, G.; Kearse, M. G.; Tsichlis, P. N.
10.1101/2024.05.22.595403 — cancer biology — Posted on 2024-05-23
1256 Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer
Oluwalana, D.; Adeleye, K. L.; Krutilina, R. I.; Chen, H.; Playa, H.; Deng, S.; Parke, D. N.; Abernathy, J.; Middleton, L.; Cullom, A.; Thalluri, B.; Ma, D.; Meibohm, B.; Miller, D. D.; Seagroves, T. N.; Li, W.
10.1101/2024.05.22.595349 — cancer biology — Posted on 2024-05-23
1257 Cardiolipin clustering promotes mitochondrial membrane dynamics
Zuccaro, K. E.; Abriata, L.; Meireles, F.; Moss, F. R.; Frost, A.; Dal Peraro, M.; Aydin, H.
10.1101/2024.05.21.595226 — biophysics — Posted on 2024-05-23
1258 Exploring the dynamics and interactions of the N-myc transactivation domain through solution NMR
Rejnowicz, E.; Batchelor, M.; Leen, E.; Ahangar, M. S.; Richards, M. W.; Kalverda, A.; Bayliss, R.
10.1101/2024.05.22.595265 — biophysics — Posted on 2024-05-23
1261 Cell-type-specific effects of autism-associated chromosome 15q11.2-13.1 duplications in human brain
Dias, C.; Mo, A.; Cai, C.; Sun, L.; Cabral, K.; Brownstein, C. A.; Rockowitz, S.; Walsh, C. A.
10.1101/2024.05.22.595175 — genetics — Posted on 2024-05-22
1262 Huntingtin CAG repeat size variations outside the Huntington's disease complex: associations with depression and anxiety phenotypes and basal ganglia structure
Vater, M.; Rost, N.; Eckstein, G.; Sauer, S.; Tontsch, A.; Erhardt, A.; Lucae, S.; Brueckl, T. M.; Klopstock, T.; Saemann, P. G.; Binder, E. B.
10.1101/2024.05.22.595390 — genetics — Posted on 2024-05-22
1265 Cyclic di-GMP as an Antitoxin Regulates Bacterial Genome Stability and Antibiotic Persistence in Biofilms
Liao, H.; Yan, X.; Wang, C.; Huang, C.; Zhang, W.; Xiao, L.; Jiang, J.; Bao, Y.; Huang, T.; Zhang, H.; Guo, C.; Zhang, Y.; Pu, Y.
10.1101/2024.05.22.595364 — microbiology — Posted on 2024-05-22
1267 Strong pairwise Interactions do not Drive Interactions in a Plant Leaf Associated Microbial Community
Hoehn, F.; Bagci, C.; Chaudhry, V.; Stincone, P.; Mahmoudi, M.; Berg, L.; Klenk, E.; Hughes, C. C.; Petras, D.; Broetz-Oesterhelt, H.; Kemen, E.; Ziemert, N.
10.1101/2024.05.22.595276 — microbiology — Posted on 2024-05-22
1269 Gene deletion as a possible strategy adopted by New World Leishmania infantum to maximize geographic dispersion
Florencio, M.; Chagas, M.; Guimaraes-Costa, A.; Oliveira, J.; Waclawiak, I.; Oliveira, T.; Saraiva, E. M.; Freitas-Mesquita, A.; Meyer-Fernandes, J. R.; Aragao-Farias, L.; Enes, C.; Cuervo, P.; Nascimento, R.; Moreira, O. C.; Ribeiro-Gomes, F.; Traub-Cseko, Y. M.; Telleria, E. L. C.; Vaselek, S.; Lestinova, T.; Volf, P.; Spaeth, G. F.; Cupolillo, E.; Boite, M. C.
10.1101/2024.05.22.595165 — microbiology — Posted on 2024-05-22
1270 Altered gut microbial functional pathways in people with Irritable Bowel Syndrome enable precision health insights
Patridge, E.; Gorakshakar, A.; Molusky, M. M.; Ogundijo, O.; Julian, C.; Hu, L.; Antoine, G.; Vuyisich, M.; Wohlman, R.; Banavar, G.
10.1101/2024.02.15.580548 — microbiology — Posted on 2024-05-22
1271 Characterization and functional analysis of Toxoplasma Golgi-associated proteins identified by proximity labelling
Pasquarelli, R. R.; Quan, J. J.; Cheng, E. S.; Yang, V.; Britton, T. A.; Sha, J.; Wohlschlegel, J. A.; Bradley, P. J.
10.1101/2024.02.02.578703 — microbiology — Posted on 2024-05-22
1272 Ornithine Lipid is a Partial TLR4 Agonist and NLRP3 Activator
Pizzuto, M.; Hurtado-Navarro, L.; Molina-Lopez, C.; Soubhye, J.; Gelbcke, M.; Rodriguez-Lopez, S.; Ruysschaert, J.-M.; Schroder, K.; Pelegrin, P.
10.1101/2022.01.28.477396 — immunology — Posted on 2024-05-22
1273 Identification of a new cell cycle variant during multiciliated cell differentiation
Serizay, J.; Khoury Damaa, M.; Boudjema, A.-R.; Balague, R.; Faucourt, M.; Delgehyr, N.; Nous, C.; Zaragosi, L.-E.; Barbry, P.; Spassky, N.; Koszul, R.; Meunier, A.
10.1101/2024.05.22.595357 — cell biology — Posted on 2024-05-22
1274 Flexible behavioral adjustment to frustrative nonreward in anticipatory behavior, but not in consummatory behavior, requires the dorsal hippocampus
Hagen, C.; Hoxha, M.; Chitale, S.; White, A. O.; Ogallar, P.; Exposito, A. N.; Aguera, A. D. R.; Torres, C.; Papini, M. R.; Sabariego, M.
10.1101/2024.05.22.595420 — neuroscience — Posted on 2024-05-22
1279 The tidyomics ecosystem: Enhancing omic data analyses
Hutchison, W. J.; Keyes, T. J.; Crowell, H. L.; Soneson, C.; Mu, W.; Park, J.-E.; Davis, E. S.; Nahid, A. A.; Tang, M.; Yuan, V.; Axisa, P.-P.; Kitt, J. W.; Poon, C.-L.; Sato, N.; Kosmac, M.; Serizay, J.; Gottardo, R.; Morgan, M.; Lee, S.; Lawrence, M.; Hicks, S. C.; Nolan, G. P.; Davis, K. L.; Papenfuss, A. T.; Love, M. I.; Mangiola, S.
10.1101/2023.09.10.557072 — bioinformatics — Posted on 2024-05-22
1281 Identifying Naturalistic Movies from Human Brain Activity with High-Density Diffuse Optical Tomography
Markow, Z. E.; Tripathy, K.; Svoboda, A. M.; Schroeder, M. L.; Rafferty, S. M.; Richter, E. J.; Eggebrecht, A. T.; Anastasio, M. A.; Chevillet, M. A.; Mugler, E. M.; Naufel, S. N.; Yin, A.; Trobaugh, J. W.; Culver, J. P.
10.1101/2023.11.27.566650 — bioengineering — Posted on 2024-05-22
1282 A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremor
Castonguay, C.-E.; Aboasali, F.; Medeiros, M.; Becret, T.; Schmilovich, Z.; Khayachi, A.; Rajput, A.; Dion, P. A.; Rouleau, G.
10.1101/2024.05.22.595233 — genomics — Posted on 2024-05-22
1284 Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation
Damaa, M. K.; SERIZAY, J.; Balague, R.; Boudjema, A.-R.; Faucourt, M.; Delgehyr, N.; Goh, K. J.; Lu, H.; Tan, E. K.; James, C. T.; Faucon, C.; Mitri, R.; Bracht, D. C.; Bingle, C. D.; Dunn, N. R.; Arnold, S. J.; Zaragosi, L.-E.; Barbry, P.; Koszul, R.; Omran, H.; Gil-Gomez, G.; Escudier, E.; Legendre, M.; Roy, S.; Spassky, N.; Meunier, A.
10.1101/2024.05.22.595363 — cell biology — Posted on 2024-05-22
1285 Norepinephrine Signals Through Astrocytes To Modulate Synapses
Lefton, K. B.; Wu, Y.; Yen, A.; Okuda, T.; Zhang, Y.; Dai, Y.; Walsh, S.; Manno, R.; Dougherty, J.; Samineni, V. K.; Simpson, P. C.; Papouin, T.
10.1101/2024.05.21.595135 — neuroscience — Posted on 2024-05-22
1288 SARS-CoV-2 sequencing artifacts associated with targeted PCR enrichment and read mapping
Ellegaard, K. M.; Gunalan, V.; Sieber, R.; Baig, S. J.; Larsen, N. B.; Bennedbaek, M.; Bybjerg-Grauholm, J.; Escobar-Herrera, L. A.; Hansen, T. N. G.; Thorsen, T. H.; Krusager, A.; Aasbjerg, G. N.; Al-Tamimi, N. S.; Westergaard, C.; Svarrer, C. W.; Rasmussen, M.; Stegger, M.
10.1101/2024.05.22.595297 — bioinformatics — Posted on 2024-05-22
1289 Structural Determinants of Vibrio cholerae FeoB Nucleotide Promiscuity
Lee, M.; Magante, K.; Gomez-Garzon, C.; Payne, S. M.; Smith, A. T.
10.1101/2024.05.22.595361 — biochemistry — Posted on 2024-05-22
1291 High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ1 riboswitch ligands
Wintermans, S.; Hoffmann, J. S.; Tacoma, M. D.; Broekhuizen, I.; van Doodewaerd, B. R.; Geurink, P. P.; Janssen, A. P. A.; Artola, M. E.; Olsthoorn, R.
10.1101/2024.05.22.595132 — biochemistry — Posted on 2024-05-22
1292 Diel Partitioning in Microbial Phosphorus Acquisition in the Sargasso Sea
Muratore, D.; Gilbert, N. E.; LeCleir, G. R.; Wilhelm, S. W.; Weitz, J. S.
10.1101/2024.03.28.587236 — ecology — Posted on 2024-05-22
1293 Influenza A virus circumvents the innate immune response through the sequestration of double-stranded RNA
Nakano, M.; Miyamoto, S.; Ohnishi, C.; Nogami, C.; Hirose, N.; Fujita, Y. F.; Muramoto, Y.; Noda, T.
10.1101/2024.05.22.595274 — microbiology — Posted on 2024-05-22
1294 Metabolic engineering of yeast for de novo production of kratom monoterpene indole alkaloids
Holtz, M.; Rago, D.; Nedermark, I.; Hansson, F. G.; Lehka, B. J.; Hansen, L. G.; Marcussen, N. E. J.; Veneman, W. J.; Ahonen, L.; Wungsintaweekul, J.; Dirks, R. P.; Acevedo-Rocha, C. G.; Zhang, J.; Keasling, J. D.; Jensen, M. K.
10.1101/2024.05.22.595370 — synthetic biology — Posted on 2024-05-22
1297 From birds to mammals: spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle led to efficient intra- and interspecies transmission
Caserta, L. C.; Frye, E. A.; Butt, S. L.; Laverack, M. A.; Nooruzzaman, M.; Covalenda, L. M.; Thompson, A.; Prarat Koscielny, M.; Cronk, B.; Johnson, A.; Kleinhenz, K.; Edwards, E. E.; Gomez, G.; Hitchener, G. R.; Martins, M.; Kapczynski, D. R.; Suarez, D. L.; Alexander Morris, E. R.; Hensley, T.; Beeby, J. S.; Lejeune, M.; Swinford, A.; Elvinger, F.; Dimitrov, K. M.; Diel, D. G.
10.1101/2024.05.22.595317 — microbiology — Posted on 2024-05-22
1304 Single-cell and single-nucleus RNA-sequencing from paired normal-adenocarcinoma lung samples provide both common and discordant biological insights
Renaut, S.; Armero, V. S.; Boudreau, D. K.; Gaudreault, N.; Desmeules, P.; Theriault, S.; Mathieu, P.; Joubert, P.; Bosse, Y.
10.1101/2024.02.20.581199 — cancer biology — Posted on 2024-05-22
1305 miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells
Nelson, H. M.; Qu, S.; Huang, L.; Shameer, M.; Corn, K. C.; Chapman, S. N.; Luthcke, N. L.; Schuster, S. A.; Turnbull, L. A.; Guy, L. L.; Liu, X.; Vickers, K. C.; Liu, Q.; Franklin, J. L.; Weaver, A.; Rafat, M.; Coffey, R. J.; Patton, J. G.
10.1101/2024.01.16.575716 — cancer biology — Posted on 2024-05-22
1308 Fast and robust objective EEG audiometry
Guyonnet-Hencke, T.; Portoles, O.; de Vries, M.; Koderman, E.; Winkler, A.; Goodall, J.; Desain, P.; Thielen, J.; Schulte, M.; Beynon, A.; van Kesteren, M.
10.1101/2024.05.22.595285 — neuroscience — Posted on 2024-05-22
1312 Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice
Martin-Avila, A.; Modak, S. R.; Rajamohamedsait, H. B.; Dodge, A.; Shamir, D. B.; Krishnaswamy, S.; Sandusky-Beltran, L. A.; Walker, M.; Lin, Y.; Congdon, E. E.; Sigurdsson, E. M.
10.1101/2024.05.21.595198 — neuroscience — Posted on 2024-05-22
1315 VesselBoost: A Python Toolbox for Small Blood Vessel Segmentation in Human Magnetic Resonance Angiography Data
Xu, M.; Ribeiro, F. L.; Barth, M.; Bernier, M.; Bollmann, S.; Chatterjee, S.; Cognolato, F.; Gulban, O. F.; Itkyal, V.; Liu, S.; Mattern, H.; Polimeni, J. R.; Shaw, T. B.; Speck, O.; Bollmann, S.
10.1101/2024.05.22.595251 — neuroscience — Posted on 2024-05-22
1317 Consistency of resting-state correlations between fMRI networks and EEG band-power
Xavier, M.; Esteves, I.; Jorge, J.; Abreu, R.; Giraud, A.-L.; Sadaghiani, S.; Wirsich, J.; Figueiredo, P.
10.1101/2024.05.22.595342 — neuroscience — Posted on 2024-05-22
1318 Cellular coordination underpins rapid reversals in gliding filamentous cyanobacteria and its loss results in plectonemes
Rosko, J.; Cremin, K.; Locatelli, E.; Coates, M.; Duxbury, S. J. N.; Randall, K.; Croft, K.; Valeriani, C.; Polin, M.; Soyer, O. S.
10.1101/2024.02.06.579126 — biophysics — Posted on 2024-05-22
1319 Single-cell and spatiotemporal profile of ovulation in the mouse ovary
Huang, R.; Kratka, C. E.; Pea, J.; McCann, C.; Nelson, J.; Bryan, J. P.; Zhou, L. T.; Russo, D. D.; Zaniker, E. J.; Gandhi, A. H.; Shalek, A. K.; Cleary, B.; Farhi, S. L.; Duncan, F. E.; Goods, B. A.
10.1101/2024.05.20.594719 — bioinformatics — Posted on 2024-05-22
1320 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery
Umansky, T.; Ramesh, N.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.
10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-05-22
1323 Spatially tuneable multi-omics sequencing using light-driven combinatorial barcoding of molecules in tissues
Battistoni, G.; Torres-Garcia, S.; Sia, C. Y.; Corriero, S.; Boquetale, C.; Williams, E. G.; Alini, M.; Hemmer, N.; IMAXT Cancer Grand Challenge Consortium, ; Balasubramanian, S.; Nicholson, B. C.; Hannon, G. J.; Bressan, D.
10.1101/2024.05.20.595040 — genomics — Posted on 2024-05-22
1324 Accelerating Genome- and Phenome-Wide Association Studies using GPUs - A case study using data from the Million Veteran Program
Rodriguez, A. A.; Kim, Y.; Nandi, T. N.; Keat, K.; Kumar, R.; Bhukar, R.; Conery, M.; Liu, M.; Hessington, J.; Begoli, E.; Tourassi, G.; Muralidhar, S.; Natarajan, P.; Voight, B. F.; Cho, K.; Gaziano, M. J.; Damrauer, S.; Liao, K. P.; Zhou, W.; Huffman, J. E.; Verma, A.; Madduri, R. K.
10.1101/2024.05.17.594583 — genetics — Posted on 2024-05-22
1325 Single cell multiomic analyses reveal divergent effects of DNMT3A and TET2 mutant clonal hematopoiesis in inflammatory response
Ismail, W. M.; Fernandez, J. A.; Binder, M.; Lasho, T. L.; Kim, M.; Geyer, S. M.; Mazzone, A.; Finke, C. M.; Mangaonkar, A. A.; Lee, J.-H.; Wang, L.; Hyun Kim, K.; Simon, V. A.; Rohakthar, F. R.; Munankarmy, A.; Byeon, S. K.; Schwager, S. M.; Harrington, J. J.; Snyder, M. R.; Robertson, K. D.; Pandey, A.; Wieben, E. D.; Chia, N.; Gaspar-Maia, A.; Patnaik, M. M.
10.1101/2022.08.25.505316 — genetics — Posted on 2024-05-22
1326 Open-ended molecular recording of sequential cellular events into DNA
Loveless, T. B.; Carlson, C. K.; Dentzel Helmy, C. A.; Hu, V. J.; Ross, S. K.; Demelo, M. C.; Murtaza, A.; Liang, G.; Ficht, M.; Singhai, A.; Pajoh-Casco, M. J.; Liu, C. C.
10.1101/2021.11.05.467507 — genetics — Posted on 2024-05-22
1331 Chromatin enhancer activity of IκBα mediates the exit from naïve pluripotency
Galan, L.; Alvarez-Villanueva, D.; Maqueda, M.; Barrero, M.; IGLESIAS, A.; Bertran, j.; ALVAREZ, D.; GARCIA-PRIETO, C.; BALLARE, C.; RODRIGUEZ-CORTEZ, V.; BUENO, C.; VIDAL, A.; Villanueva, A.; Menendez, P.; Stik, G.; Di Croce, L.; Payer, B.; Esteller, M.; Espinosa, L.; Bigas, A.
10.1101/2023.07.28.550934 — cell biology — Posted on 2024-05-22
1332 The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy
Mathavarajah, S.; Habib, E. B.; Kim, W. D.; Aoki, M. M.; Corkery, D. P.; Whelan, K. I. T.; Lukacs, J.; Salsman, J.; Huber, R. J.; Dellaire, G.
10.1101/2024.05.21.595022 — cell biology — Posted on 2024-05-22
1333 Mapping the soil microbiome functions shaping wetland methane emissions
Oliverio, A. M.; Narrowe, A. B.; Villa, J. A.; Rinke, C.; Hoyt, D. W.; Liu, P.; McGivern, B. B.; Bechtold, E. K.; Ellenbogen, J. B.; Daly, R. A.; Smith, G. J.; Angle, J. C.; Flynn, R. M.; Freiburger, A. P.; Louie, K. B.; Stemple, B.; Northen, T.; Henry, C.; Miller, C.; Morin, T. H.; Bohrer, G.; Borton, M. A.; Wrighton, K. C.
10.1101/2024.02.06.579222 — microbiology — Posted on 2024-05-22
1337 Astrocytic hemoglobin is an H2O2-decomposing peroxidase and therapeutic target for Alzheimer's disease
Won, W.; Lee, E.; Gotina, L.; Chun, H.; Park, U.; Kim, D.; Kim, T. Y.; Choi, J.; Kim, Y.; Park, S. J.; Bhalla, M.; Lim, J.; Park, J.-H.; Oh, S.-J.; Ryu, H.; Pae, A. N.; Park, K.; Lee, C. J.
10.1101/2024.05.21.594979 — neuroscience — Posted on 2024-05-22
1339 Tau pathology leads to lonely non-traveling slow waves that mediate human memory impairment
Sharon, O.; Chen, X.; Dude, J.; Shah, V. D.; Ju, Y.-E. S.; Jagust, W. J.; Walker, M. P.
10.1101/2024.05.22.595043 — neuroscience — Posted on 2024-05-22
1341 The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease
Bhalla, S. R.; Wahid, M.; Amartey, J.; Riu, F.; Gao, Y.; Agrawal, J.; Lynch, A. P.; Machado, M. J.; Hawtrey, T.; Kikuchi, R.; Green, K. R.; Teboul, L.; Allen, C.; Blackley, Z.; Rajaji, K.; Marsden, D.; Batson, J.; Harper, S. J.; Oltean, S.; Amoaku, W.; Benest, A. V.; Morris, J. C.; Braithwaite, B.; Bates, D. O.
10.1101/2024.04.17.589996 — physiology — Posted on 2024-05-22
1342 RBM39 shapes innate immunity through transcriptional and splicing control of key factors of the interferon response
Li, T.-F.; Rothhaar, P.; Lang, A.; Gruenvogel, O.; Colasanti, O.; Olivera Ugarte, S. M.; Traut, J.; Piras, A.; Acosta-Rivero, N.; Goncalves Magalhaes, V.; Springer, E.; Betz, A.; Huang, H.-E.; Park, J.; Qiu, R.; Gnouamozi, G. E.; Mehnert, A.-K.; Dao Thi, V. L.; Urban, S.; Muckenthaler, M.; Schlesner, M.; Wohlleber, D.; Binder, M.; Bartenschlager, R.; Pichlmair, A.; Lohmann, V.
10.1101/2023.10.13.562221 — immunology — Posted on 2024-05-22
1343 Amphibian mast cells: barriers to chytrid fungus infections
Hauser, K. A.; Garvey, C. N.; Crow, R. S.; Hossainey, M. R. H.; Howard, D. T.; Ranganathan, N.; Gentry, L. K.; Yaparla, A.; Kalia, N.; Zelle, M.; Jones, E. J.; Duttargi, A. N.; Rollins-Smith, L. A.; Muletz-Wolz, C. R.; Grayfer, L.
10.1101/2023.09.29.560127 — immunology — Posted on 2024-05-22
1344 The impact of Parkinson's disease on striatal network connectivity and cortico-striatal drive: an in-silico study
Carannante, I.; Scolamiero, M.; Hjorth, J.; Kozlov, A.; Bekkouche, B.; Guo, L.; Kumar, A.; Chacholski, W.; Hellgren Kotaleski, J.
10.1101/2023.09.15.557977 — neuroscience — Posted on 2024-05-22
1347 AlbuMAX supplemented media induces the formation of transmission-competent P. falciparum gametocytes
Graumans, W.; Starre, A. v. d.; Stoter, R.; Gemert, G.-J. v.; Andolina, C.; Ramjith, J.; Kooij, T. W. A.; Bousema, T.; Proellochs, N.
10.1101/2024.04.05.588064 — microbiology — Posted on 2024-05-22
1349 A peptide that regulates metalation and function of the Arabidopsis ethylene receptor.
Mudge, A. M.; Mehdi, S.; Michaels, W. E.; Oroza-Puente, B.; Shen, W.; Tomlinson, C.; Wei, W.; Hoppen, C.; Uzun, B.; Roy, D.; Hetherington, F. M.; Topping, J. F.; Sadanandom, A.; Groth, G.; Robinson, N. J.; Lindsey, K.
10.1101/2023.06.15.545071 — plant biology — Posted on 2024-05-22
1352 CountASAP: A Lightweight, Easy to Use Python Package for Processing ASAPseq Data
Boughter, C. T.; Chatterjee, B.; Ohta, Y.; Gorga, K.; Blair, C.; Hill, E. M.; Fasana, Z.; Adebamowo, A.; Ammar, F.; Kosik, I.; Murugan, V.; Chen, W. H.; Singh, N. J.; Meier-Schellersheim, M.
10.1101/2024.05.20.595042 — bioinformatics — Posted on 2024-05-22
1353 Pervasive ancestry bias in variant effect predictors
Pathak, A. K.; Bora, N.; Badonyi, M.; Livesey, B. J.; Ngeow, J.; Marsh, J. A.
10.1101/2024.05.20.594987 — bioinformatics — Posted on 2024-05-22
1354 Spatially tuneable multi-omics sequencing using light-driven combinatorial barcoding of molecules in tissues
Battistoni, G.; Garcia, S. T.; Sia, C. Y.; Corriero, S.; Boquetale, C.; Williams, E. G.; Alini, M.; Hemmer, N.; IMAXT Cancer Grand Challenge Consortium, ; Balasubramanian, S.; Nicholson, B. C.; Hannon, G. J.; Bressan, D.
10.1101/2024.05.20.595040 — genomics — Posted on 2024-05-22
1355 Segregation between an ornamental and a disease driver gene provides insights into pigment cell regulation
Soria, E.; Lu, Q.; Boswell, W.; Du, K.; Xing, Y.; Boswell, M.; Weldon, K.; Lai, Z.; Savage, M.; Schartl, M.; Lu, Y.
10.1101/2024.05.20.595041 — genetics — Posted on 2024-05-22
1357 Inheritance of somatic mutations can affect fitness in monkeyflowers
Streisfeld, M. A.; Crown, J. C.; McLean, J. J.; Short, A. W.; Cruzan, M. B.
10.1101/2024.05.20.595007 — evolutionary biology — Posted on 2024-05-22
1360 MEM-based pangenome indexing for k-mer queries
Hwang, S.; Brown, N. K.; Ahmed, O. Y.; Jenike, K. M.; Kovaka, S.; Schatz, M. C.; Langmead, B.
10.1101/2024.05.20.595044 — bioinformatics — Posted on 2024-05-22
1361 Single-cell and spatiotemporal profile of ovulation in the mouse ovary
Huang, R.; Kratka, C. E.; Pea, J.; McCann, C.; Nelson, J.; Bryan, J. P.; Zhou, L. T.; Russo, D. D.; Zaniker, E. J.; Gandhi, A. H.; Shalek, A. K.; Cleary, B.; Farhi, S. L.; Duncan, F. E.; Goods, B. A.
10.1101/2024.05.20.594719 — bioinformatics — Posted on 2024-05-22
1363 Genetic regulation of lncRNA expression in the whole human brain
He, Y.; Tang, Y.; Tan, P.; Huang, D.; Wang, Y.; Wen, T.; Huang, L.; Wang, J.; Shao, L.; Cai, Q.; Li, Z.; Wang, Y.; Liu, T.; Han, Z.
10.1101/2024.05.20.594968 — bioinformatics — Posted on 2024-05-22
1365 A chromosome-level genome assembly of the varied leaved jewelflower, Streptanthus diversifolius, reveals a recent whole genome duplication
Davis, J. T.; Li, Q.; Grassa, C. J.; Davis, M.; Strauss, S. Y.; Gremer, J. R.; Rieseberg, L. H.; Maloof, J. N.
10.1101/2024.05.20.595032 — genomics — Posted on 2024-05-22
1366 Kinship analysis and pedigree reconstruction by RAD sequencing in cattle
Xu, Y.; Wang, W.; Xu, M.; Wang, B.; Huang, J.; Wu, Y.; Xie, Y.; Jian, J.
10.1101/2024.05.20.595066 — genomics — Posted on 2024-05-22
1367 Compartmentalization of Transcripts During Antibody Mediated Rejection in Renal Transplants
Margeta, D.; Noguchi, H.; Khazaie, S.; Herlitz, L. C.; Augustine, J. J.; Heeger, P. S.; Tambur, A. R.; Fairchild, R. L.; Baldwin, W. M.
10.1101/2024.05.20.594331 — pathology — Posted on 2024-05-22
1369 A complete and dynamic tree of birds
McTavish, E. J.; Gerbracht, J. A.; Holder, M. T.; Iliff, M. J.; Lepage, D.; Rasmussen, P. C.; Redelings, B.; Sanchez-Reyes, L. L.; Miller, E. T.
10.1101/2024.05.20.595017 — evolutionary biology — Posted on 2024-05-22
1371 Volumetric analysis of the terminal ductal lobular unit architecture and cell phenotypes in the human breast
Paavolainen, O.; Peurla, M.; Koskinen, L. M.; Pohjankukka, J.; Saberi, K.; Tammelin, E.; Sulander, S.-R.; Valkonen, M.; Mourao, L.; Boström, P.; Brück, N.; Ruusuvuori, P.; Scheele, C. L.; Hartiala, P.; Peuhu, E.
10.1101/2023.03.12.532249 — developmental biology — Posted on 2024-05-22
1375 The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease
Bhalla, S. R.; Wahid, M.; Amartey, J.; Riu, F.; Gao, Y.; Agrawal, J.; Lynch, A. P.; Hawtrey, T.; Kikuchi, R.; Green, K. R.; Teboul, L.; Allen, C.; Blackley, Z.; Rajaji, K.; Marsden, D.; Batson, J.; Harper, S. J.; Oltean, S.; Amoaku, W.; Benest, A. V.; Morris, J. C.; Braithwaite, B.; Bates, D. O.
10.1101/2024.04.17.589996 — physiology — Posted on 2024-05-22
1376 Anomalous diffusion analysis reveals cooperative locomotion of adult parasitic nematodes in sex-mixed groups.
Leben, R.; Rausch, S.; Elomaa, L.; Hauser, A. E.; Weinhart, M.; Fischer, S. C.; Stark, H.; Hartmann, S.; Niesner, R. A.
10.1101/2024.04.29.591609 — biophysics — Posted on 2024-05-22
1378 BioInformatics Agent (BIA): Unleashing the Power of Large Language Models to Reshape Bioinformatics Workflow
Xin, Q.; Kong, Q.; Ji, H.; Shen, Y.; Liu, Y.; Sun, Y.; Zhang, Z.; Li, Z.; Xia, X.; Deng, B.; Bai, Y.
10.1101/2024.05.22.595240 — bioinformatics — Posted on 2024-05-22
1380 Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids
Shimonosono, M.; Morimoto, M.; Hirose, W.; Tomita, Y.; Matsuura, N.; Flashner, S.; Ebadi, M. S.; Okayasu, E. H.; Lee, C. Y.; Britton, W. R.; Martin, C.; Wuertz, B. R.; Parikh, A. S.; Sachdeva, U. M.; Ondrey, F. G.; Atigadda, V. R.; Elmets, C. A.; Abrams, J.; Muir, A. B.; Klein-Szanto, A. J.; Weinberg, K. I.; Momen-Heravi, F.; Nakagawa, H.
10.1101/2024.05.20.595023 — cell biology — Posted on 2024-05-22
1382 Liquid-like condensates that bind actin drive filament polymerization and bundling
Walker, C.; Chandrasekaran, A.; Mansour, D.; Graham, K.; Torres, A.; Wang, L.; Lafer, E. M.; Rangamani, P.; Stachowiak, J.
10.1101/2024.05.04.592527 — biophysics — Posted on 2024-05-22
1391 Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex
Fernandez-Casanas, M.; Karanika, E.; Olukoga, T.; Herbert, A.; Aliyaskarova, U.; Day, M.; Chan, K.-L.
10.1101/2024.05.21.595148 — cell biology — Posted on 2024-05-22
1392 SARS-CoV-2 variants from long-term, persistently infected immunocompromised patients have altered syncytia formation, temperature-dependent replication, and serum neutralizing antibody escape
Wouters, C.; Sachithanandham, J.; Akin, E.; Pieterse, L.; Fall, A.; Truong, T. T.; Bard, J. D.; Yee, R.; Sullivan, D. J.; Mostafa, H. H.; Pekosz, A.
10.1101/2024.05.18.594818 — microbiology — Posted on 2024-05-22
1395 The Observed T cell receptor Space database enables paired-chain repertoire mining, coherence analysis and language modelling
Raybould, M. I. J.; Greenshields-Watson, A.; Agarwal, P.; Aguilar-Sanjuan, B.; Olsen, T. H.; Turnbull, O. M.; Quast, N. P.; Deane, C. M.
10.1101/2024.05.20.594960 — immunology — Posted on 2024-05-22
1396 Direct observation of the neural computations underlying a single decision
Steinemann, N. A.; Stine, G. M.; Trautmann, E. M.; Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.
10.1101/2022.05.02.490321 — neuroscience — Posted on 2024-05-22
1402 Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage
Boerner, K.; Blood, P. D.; Silverstein, J. C.; Ruffalo, M.; Teichmann, S. A.; Pryhuber, G.; Misra, R. S.; Purkerson, J. M.; Fan, J.; Hickey, J. W.; Molla, G.; Xu, C.; Zhang, Y.; Weber, G. M.; Jain, Y.; Qaurooni, D.; Kong, Y.; Bueckle, A.; Herr, B. W.
10.1101/2024.03.27.587041 — bioinformatics — Posted on 2024-05-22
1403 Exploring the conformational ensembles of protein-protein complex with transformer-based generative model
Wang, J.; Wang, X.; Chu, Y.; Li, C.; Li, X.; Meng, X.; Fang, Y.; No, K. T.; Mao, J.; Zeng, X.
10.1101/2024.02.24.581708 — bioinformatics — Posted on 2024-05-22
1404 Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage
Rabinowitz, R.; Shor, O.; Zerbib, J.; Herman, S.; Zelikson, N.; Madiwale, S.; Yom-Tov, N.; Ben-David, U.; Benninger, F.; Offen, D.
10.1101/2023.04.11.536265 — bioengineering — Posted on 2024-05-22
1407 Recruitment of CTCF to the SIRT1 promoter after Oxidative Stress mediates Cardioprotective Transcription
Wagner, T.; Priyanka, P.; Micheletti, R.; Friedman, M. J.; Nair, S. J.; Gamliel, A.; Taylor, H.; Song, X.; Cho, M.; Oh, S.; Li, W.; Han, J.; Ohgi, K. A.; Abrass, M.; D'Antonio-Chronowska, A.; D'Antonio, M.; Hazuda, H.; Duggirala, R.; Blangero, J.; Ding, S.; Guzmann, C.; Frazer, K. A.; Aggarwal, A. K.; Zemljic-Harpf, A. E.; Rosenfeld, M. G.; Suh, Y.
10.1101/2024.05.17.594600 — cell biology — Posted on 2024-05-22
1411 Astrocytic RIPK3 exerts protective anti-inflammatory activity during viral encephalitis via induction of serpin protease inhibitors.
Lindman, M.; Estevez, I.; Marmut, E.; DaPrano, E. M.; Chou, T.-W.; Newman, K.; Atkins, C.; O'Brown, N. M.; Daniels, B. P.
10.1101/2024.05.21.595181 — immunology — Posted on 2024-05-22
1412 Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals
Cohen, A. A.; Keeffe, J. R.; Schiepers, A.; Dross, S. E.; Greaney, A. J.; Rorick, A. V.; Gao, H.; Gnanapragasam, P. N. P.; Fan, C.; West, A. P.; Ramsingh, A. I.; Erasmus, J. H.; Pata, J. D.; Muramatsu, H.; Pardi, N.; Lin, P. J. C.; Baxter, S.; Cruz, R.; Quintanar-Audelo, M.; Robb, E.; Serrano-Amatriain, C.; Magneschi, L.; Fotheringham, I. G.; Fuller, D. H.; Victora, G. D.; Bjorkman, P. J.
10.1101/2024.02.08.576722 — immunology — Posted on 2024-05-22
1414 ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination
Li, H.; Chatla, S.; Liu, X.; Tian, Z.; Vekariya, U.; Wang, P.; Kim, D.; Octaviani, S.; Lian, Z.; Morton, G.; Feng, Z.; Yang, D.; Sullivan-Reed, K.; Childers, W.; Yu, X.; Chitrala, K. N.; Madzo, J.; Skorski, T.; Huang, J.
10.1101/2022.09.29.510119 — cancer biology — Posted on 2024-05-22
1416 Protein codes promote selective subcellular compartmentalization
Kilgore, H.; Chinn, I.; Mikhael, P.; Mitnikov, I.; Van Dongen, C.; Zylberberg, G.; Afeyan, L.; Banani, S.; Wilson-Hawken, S.; Lee, T.; Barzialy, R.; Young, R.
10.1101/2024.04.15.589616 — biochemistry — Posted on 2024-05-22
1417 Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity
Sayeed, K.; Parameswaran, S.; Beucler, M. J.; Edsall, L. E.; VonHandorf, A.; Crowther, A.; Donmez, O. A.; Hass, M. R.; Richards, S.; Forney, C. R.; Wright, J.; Leong, M. M.; Murray-Nerger, L. A.; Gewurz, B. E.; Kaufman, K. M.; Harley, J. B.; Zhao, B.; Miller, W. E.; Kottyan, L. C.; Weirauch, M. T.
10.1101/2024.04.12.588762 — genomics — Posted on 2024-05-22
1418 Evolution of sex differences in cooperation: the role of trade-offs with dispersal
Capilla-Lasheras, P.; Bircher, N.; Brown, A.; Harrison, X.; Reed, T. E.; York, J.; Cram, D.; Rutz, C.; Walker, L.; Naguib, M.; Young, A.
10.1101/2023.09.13.557370 — evolutionary biology — Posted on 2024-05-22
1419 Archaic introgression contributed to shape the adaptive modulation of angiogenesis and cardiovascular traits in human high-altitude populations from the Himalayas
Ferraretti, G.; Abondio, P.; Alberti, M.; Dezi, A.; Sherpa, P. T.; Cocco, P.; Tiriticco, M.; Di Marcello, M.; Gnecchi-Ruscone, G. A.; Natali, L.; Corcelli, A.; Marinelli, G.; Peluzzi, D.; Sarno, S.; Sazzini, M.
10.1101/2023.05.23.540768 — evolutionary biology — Posted on 2024-05-22
1420 In-depth immunometabolic profiling by measuring cellular protein translation inhibition via bioorthogonal noncanonical amino acid tagging (CENCAT)
Vrieling, F.; van der Zande, H. J. P.; Naus, B.; Smeehuijzen, L.; Ignacio, B. J.; Bonger, K. M.; van den Bossche, J.; Kersten, S.; Stienstra, R.
10.1101/2023.08.03.551800 — immunology — Posted on 2024-05-22
1421 Association of 10 VEGF Family Genes with Alzheimer's Disease Endophenotypes at Single Cell Resolution
Wu, Y.; Libby, J. B.; Dumitrescu, L.; De Jager, P. L.; Menon, V.; Schneider, J. A.; Bennett, D. A.; Hohman, T. J.
10.1101/2024.04.12.589221 — neuroscience — Posted on 2024-05-22
1422 Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release
Zhou, X.; Stine, C.; Prada, P. O.; Fusca, D.; Assoumou, K.; Dernic, J.; Bhat, M. A.; Achanta, A. S.; Johnson, J. C.; Jadhav, S.; Bauder, C. A.; Steuernagel, L.; Ravotto, L.; Benke, D.; Weber, B.; Stoeber, M.; Kloppenburg, P.; Bruening, J. C.; Bruchas, M. R.; Patriarchi, T.
10.1101/2023.05.26.542102 — neuroscience — Posted on 2024-05-22
1423 Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in large-scale thalamocortical network model of the human brain
Marsh, B.; Zuloaga, M. G. N.; Rosen, B. Q.; Sokolov, Y.; Delanois, J. E.; Gonzalez, O. C.; Krishnan, G. P.; Halgren, E.; Bazhenov, M.
10.1101/2023.10.15.562408 — neuroscience — Posted on 2024-05-22
1427 Large scale loss-of-function mutations during chicken evolution and domestication
Wu, S.; Wang, K.; Ge, X.; Dou, T.; Yuan, S.; Yan, S.; Xu, Z.; Liu, Y.; Jian, Z.; Zhao, J.; Zhao, R.; Zi, X.; Gu, D.; Liu, L.; Li, Q.; Wu, D.-D.; Jia, J.; Ge, C.; Su, Z.
10.1101/2024.05.21.595210 — bioinformatics — Posted on 2024-05-22
1430 Norepinephrine Signals Through Astrocytes To Modulate Synapses
Lefton, K. B.; Wu, Y.; Yen, A.; Okuda, T.; Zhang, Y.; Dai, Y.; Walsh, S.; Manno, R.; Dougherty, J.; Samineni, V. K.; Simpson, P. C.; Papouin, T.
10.1101/2024.05.21.595135 — neuroscience — Posted on 2024-05-22
1431 Temporal Coherence Shapes Cortical Responses to Speech Mixtures in a Ferret Cocktail Party
Joshi, N.; Ng, Y.; Thakkkar, K.; Duque, D.; Yin, P.; Fritz, J.; Elhilali, M.; Shamma, S.
10.1101/2024.05.21.595171 — neuroscience — Posted on 2024-05-22
1433 Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases
Karlsson, J. W.; Sah, V. R.; Olofsson Bagge, R.; Kuznetsova, I.; Iqba, M.; Alsen, S.; Stenqvist, S.; Saxena, A.; Ny, L.; Nilsson, L.; Nilsson, J. A.
10.1101/2023.05.16.540908 — cancer biology — Posted on 2024-05-21
1434 RNA Polymerase II hypertranscription in cancer FFPE samples
Henikoff, S.; Henikoff, J. G.; Paranal, R. M.; Greene, J. E.; Zheng, Y.; Russell, Z. R.; Szulzewsky, F.; Kugel, S.; Holland, E. C.; Ahmad, K.
10.1101/2024.02.28.582647 — cancer biology — Posted on 2024-05-21
1435 Topological Structures in the Space of Treatment-Naive Patients With Chronic Lymphocytic Leukemia
McGee, R. L.; Reed, J.; Coombes, C. E.; Herling, C. D.; Keating, M. J.; Abruzzo, L. V.; Coombes, K. R.
10.1101/2024.05.16.593927 — bioinformatics — Posted on 2024-05-21
1437 Temperature-Dependent Fold-Switching Mechanism of the Circadian Clock Protein KaiB
Liwang, A.; Dinner, A.; Sosnick, T.; Wang, L.-P.; Partch, C. L.; Zhang, N.; Sood, D.; Guo, S.; Chen, N.; Baxa, M.; Chavan, A.; Hong, L.; Antoszewski, A.; Marianchuk, T.; Peng, X.; Xiao, Y.; Dey, S.
10.1101/2024.05.21.594594 — biochemistry — Posted on 2024-05-21
1438 The major surface protein of malaria sporozoites is GPI-anchored to the plasma membrane
Nagar, R.; Castillo, S. S. G.; Pinzon-Ortiz, M.; Patray, S.; Coppi, A.; Kanatani, S.; Moritz, R. L.; Swearingen, K. E.; Ferguson, M. A. J.; Sinnis, P.
10.1101/2024.05.21.595204 — biochemistry — Posted on 2024-05-21
1440 Characteristics of JN.1-derived SARS-CoV-2 subvariants SLip, FLiRT, and KP.2 in neutralization escape, infectivity and membrane fusion
Li, P.; Faraone, J. N.; Hsu, C. C.; Chamblee, M.; Zheng, Y.-M.; Carlin, C.; Bednash, J. S.; Horowitz, J. C.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Jones, D.; Li, J.; Gumina, R. J.; Xu, K.; Liu, S.-L.
10.1101/2024.05.20.595020 — microbiology — Posted on 2024-05-21
1443 A safe insect-based Chikungunya fever vaccine affords rapid and durable protection in cynomolgus macaques
Adam, A.; Woolsey, C.; Lu, H.; Plante, K. S.; Wallace, S. M.; Rodriguez, L.; Shinde, D. P.; Cui, Y.; Franz, A. W. E.; Thangamani, S.; Comer, J. E.; Weaver, S. C.; Wang, T.
10.1101/2024.05.21.595029 — microbiology — Posted on 2024-05-21
1444 Inducible transposon mutagenesis for genome-scale forward genetics
Basta, D. W.; Campbell, I. W.; Sullivan, E. J.; Hotinger, J. A.; Hullahalli, K.; Waldor, M. K.
10.1101/2024.05.21.595064 — microbiology — Posted on 2024-05-21
1449 Unraveling factors responsible for pathogenic differences in Lassa virus strains
Taniguchi, S.; Saito, T.; Paroha, R.; Huang, C.; Paessler, S.; Maruyama, J.
10.1101/2024.05.21.595091 — microbiology — Posted on 2024-05-21
1450 Viral and host network analysis of the human cytomegalovirus transcriptome in latency.
Collins-McMillen, D. K.; De Oliveira Pessoa, D.; Zarrella, K.; Parkins, C. J.; Daily, M.; Moorman, N. K.; Kamil, J. P.; Caposio, P.; Padi, M.; Goodrum, F.
10.1101/2024.05.21.594597 — microbiology — Posted on 2024-05-21
1451 Virus propagation linked to exceedingly rare gene-expression errors
Luzon-Hidalgo, R.; D'Agostino, G.; Risso, V. A.; Delgado, A.; Ibarra-Molero, B.; Campos, L. A.; Requejo-Isidro, J.; Sanchez-Ruiz, J. M.
10.1101/2024.05.21.595180 — microbiology — Posted on 2024-05-21
1452 Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections
Ngo, C.; Rahmani, K.; Valente, M.; Collinet, N.; Bessou, G.; Fabregue, M.; Sharkaoui, S.; Mazzoli, S.; Pierini-Malosse, C.; Sansoni, A.; Fiore, F.; Laprie, C.; GAYA, M.; Gregoire, C.; Broggi, A.; Milpied, P.; Escaliere, B.; Phong, T.; Fallet, M.; Chasson, L.; Tran, H.; Le Bert, M.; Malissen, B.; ZARUBICA, A.; DALOD, M.; Tomasello, E.
10.1101/2024.05.20.594961 — immunology — Posted on 2024-05-21
1453 Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade
Arulraj, T.; Wang, H.; Deshpande, A.; Varadhan, R.; Emens, L. A.; Jaffee, E. M.; Fertig, E. J.; Santa-Maria, C. A.; Popel, A. S.
10.1101/2024.05.21.595235 — systems biology — Posted on 2024-05-21
1455 Impact of Organic Compounds on the Stability of Influenza A Virus in deposited 1-ul droplets
Schaub, A.; David, S. C.; Glas, I.; Klein, L. K.; Violaki, K.; Terrettaz, C.; Motos, G.; Bluvshtein, N.; Luo, B.; Pohl, M. O.; Hugentobler, W.; Nenes, A.; Krieger, U. K.; Peter, T.; Stertz, S.; Kohn, T.
10.1101/2024.05.20.595000 — microbiology — Posted on 2024-05-21
1456 Histologic variants in bladder cancer harbor aggressive molecular features including TM4SF1 expression and a CA125+ cell state
Yang, H.; Song, H.; Yip, E.; Chang, K.; Allegakoen, P.; Lu, K. L.; Hui, K.; Pham, J.; Kasap, C.; Kumar, V.; Gayle, J.; Stohr, B. A.; Ding, C.-K. C.; Wiita, A. P.; Meng, M. V.; Chou, J.; Porten, S. P.; Huang, F. W.
10.1101/2024.05.20.595039 — cancer biology — Posted on 2024-05-21
1460 Reconstructing prehistoric viral genomes from Neanderthal sequencing data
Ferreira, R. C.; Alves, G. V.; Ramon, M.; Antoneli, F. M.; Briones, M. R.
10.1101/2023.03.16.532919 — genomics — Posted on 2024-05-21
1463 BCOR-Rearranged Sarcomas: In Silico Insights into Altered Domains and Reduced RAWUL-PUFD Binding
Madarasz, K.; Motyan, J. A.; Chien, Y.-C. C.; Bedekovics, J.; Csoma, S. L.; Mehes, G.; Mokanszki, A.
10.1101/2024.05.21.595144 — molecular biology — Posted on 2024-05-21
1465 Long-term efficacy of adoptive cell therapy is determined by host CD8+ T cells and undermined by lymphodepleting preconditioning
Figueroa, D.; Vega, J. P.; Hernandez-Oliveras, A.; Galvez-Cancino, F.; Ardiles, F.; Flores, F.; Hidalgo, S.; Lopez, X.; Gonzalez, H.; Osorio, F.; Borgna, V.; Lladser, A.
10.1101/2024.05.16.594554 — immunology — Posted on 2024-05-21
1470 Genetic evidence for functional diversification of gram-negative intermembrane phospholipid transporters
Rai, A. K.; Sawasato, K.; Bennett, H. C.; Kozlova, A.; Sparagna, G. C.; Bogdanov, M.; Mitchell, A. M.
10.1101/2023.06.21.545913 — microbiology — Posted on 2024-05-21
1474 Angiotensin Converting Enzyme (ACE) expression in microglia reduces amyloid β deposition and neurodegeneration by increasing SYK signaling and endolysosomal trafficking.
Gomez, A. R.; Byun, H. R.; Wu, S.; Muhammad, A. G.; Ikbariyeh, J.; Chen, J.; Muro, A.; LI, L.; Bernstein, K. E.; Ainsworth, R.; Tourtellotte, W. G.
10.1101/2024.04.24.590837 — neuroscience — Posted on 2024-05-21
1475 Medial temporal lobe atrophy patterns in early- versus late-onset amnestic Alzheimer's disease
Wuestefeld, A.; Pichet Binette, A.; van Westen, D.; Strandberg, O.; Stomrud, E.; Mattsson-Carlgren, N.; Janelidze, S.; Smith, R.; Palmqvist, S.; Baumeister, H.; Berron, D.; Yushkevich, P. A.; Hansson, O.; Spotorno, N.; Wisse, L.
10.1101/2024.05.21.594976 — neuroscience — Posted on 2024-05-21
1477 MHConstructor: A high-throughput, haplotype-informed solution to the MHC assembly challenge
Wade, K. J.; Suseno, R.; Kizer, K.; Williams, J.; Boquett, J.; Caillier, S.; Pollock, N. R.; Renschen, A.; Santaniello, A.; Oksenberg, J. R.; Norman, P. J.; Augusto, D. G.; Hollenbach, J. A.
10.1101/2024.05.20.595060 — bioinformatics — Posted on 2024-05-21
1478 Conditional language models enable the efficient design of proficient enzymes
Munsamy, G.; Illanes-Vicioso, R.; Fruncillo, S.; Nakou, I. T.; Lindner, S.; Ayres, G.; Sheehan, L. S.; Moss, S.; Eckhard, U.; Lorenz, P.; Ferruz, N.
10.1101/2024.05.03.592223 — bioinformatics — Posted on 2024-05-21
1480 The intracellular symbiont Wolbachia alters Drosophila development and metabolism to buffer against nutritional stress
Lindsey, A. R.; Tennessen, J.; Gelaw, M. A.; Jones, M. W.; Parish, A. J.; Newton, I. L.; Nemkov, T.; D'Alessandro, A.; Rai, M.; Stark, N.
10.1101/2023.01.20.524972 — developmental biology — Posted on 2024-05-21
1481 Yes Associated Transcriptional Regulator 1 (YAP1) and WW Domain Containing Transcription Regulator (WWTR1) are required for murine pregnancy initiation
Moldovan, G. E.; Massri, N.; Vegter, E. L.; Pauneto-Delgado, I. N.; Burns, G. W.; Joshi, N.; Gu, B.; Arora, R.; Fazleabas, A. T.
10.1101/2024.05.09.592984 — molecular biology — Posted on 2024-05-21
1482 Anaerobiosis modulates the performance of antimicrobial resistance genes in Enterobacterales
Ortiz, L.; Prieto, A.; Kieffer, N.; Vergara, E.; Canton, R.; San Millan, A.; Baquero, F.; Hipolito, A.; Escudero, J. A.
10.1101/2024.05.17.594675 — microbiology — Posted on 2024-05-21
1486 The exogenous application of the apocarotenoid retinaldehyde negatively regulates auxin-mediated root growth
Xu, K.; Zeng, H.; Lin, F.; Yumoto, E.; Asahina, M.; Hayashi, K.-i.; Fukaki, H.; Ito, H.; Watahiki, M. K.
10.1101/2023.09.12.555306 — plant biology — Posted on 2024-05-21
1490 Ultra-stable insulin-glucagon fusion protein exploits an endogenous hepatic switch to mitigate hypoglycemic risk
Varas, N.; Grabowski, R.; Jarosinski, M. A.; Tai, N.; Herzog, R. I.; Ismail-Beigi, F.; Yang, Y.; Cherrington, A. D.; Weiss, M. A.
10.1101/2024.05.20.594997 — bioengineering — Posted on 2024-05-21
1493 Predictive biomarkers of breast ductal carcinoma in situ may underestimate the risk of recurrence due to de novo ipsilateral breast carcinoma development
Kader, T.; Zethoven, M.; Mahale, S.; Saunders, H.; Tjoeka, L.; Lehmann, R.; Jayawardane, M.; Pang, J.-M.; Lesche, D.; Rajan, N.; Semple, T.; Lee, J. E. A.; Lupat, R.; Byrne, D. J.; Hughes, S.; Nguyen, H.; Lai, S.; Pechlivanis, M.; Craig, O.; Devereux, L.; House, E.; Jayasinghe, S. I.; Kaufmann, T. L.; Schwarz, R. F.; Green, A. R.; Miligy, I.; Cummings, M.; Lakhani, S.; Campbell, I. G.; Rakha, E.; Fox, S. B.; Mann, G. B.; Gorringe, K. L.
10.1101/2024.05.19.594731 — cancer biology — Posted on 2024-05-21
1494 The transcriptional landscape of metastatic hormone-naive prostate cancer
Martin-Martin, N.; Garcia-Longarte, S.; Corres-Mendizabal, J.; Lazcano, U.; Astobiza, I.; Bozal-Basterra, L.; Herranz, N.; van Splunder, H.; Carlevaris, O.; Pujana-Vaquerizo, M.; Blasco, M. T.; Aransay, A. M.; Rosino, A.; Tudela, J.; Jimenez, D.; Martinez, A.; Salca, A.; Santos-Martin, A.; Rey, S.; Ugalde-Olano, A.; Gonzalo, D.; Graupera, M.; Gomis, R. R.; Mateo, J.; Unda, M.; Gonzalez-Billalabeitia, E.; Loizaga-Iriarte, A.; Mendizabal, I.; Carracedo, A.
10.1101/2024.05.20.594913 — cancer biology — Posted on 2024-05-21
1496 p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis
Wittke, C. I.; Cheung, E. C.; Athineos, D.; Clements, N.; Butler, L.; Hughes, M.; Morrison, V.; Watt, D.; Blyth, K.; Vousden, K.; Humpton, T. J.
10.1101/2024.05.20.594983 — cancer biology — Posted on 2024-05-21
1497 Lack of TGFβ signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade
Moore, J.; Gkantalis, J.; Guix, I.; Chou, W.; Yuen, K.; Lazar, A.; Spitzer, M. H.; Combes, A.; Barcellos-Hoff, M. H.
10.1101/2024.03.06.583752 — cancer biology — Posted on 2024-05-21
1498 Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform
Jiang, W.; Shaw, S.; Rush, J.; Dumont, N.; Kim, J.; Singh, R.; Skepner, A.; Khodier, C.; Raffier, C.; Yan, N.; Schluter, C.; Yu, X.; Szuchnicki, M.; Sathappa, M.; Kahn, J.; Sperling, A. S.; McKinney, D. C.; Gould, A. E.; Garvie, C. W.; Miller, P. G.
10.1101/2024.05.20.595001 — cancer biology — Posted on 2024-05-21
1502 CONSTITUTIVE OPENING OF THE Kv7.2 PORE ACTIVATION GATE CAUSES KCNQ2-DEVELOPMENTAL ENCEPHALOPATHY
Nappi, M.; Alberini, G.; Berselli, A.; Roscioni, A.; Soldovieri, M. V.; Barrese, V.; Weckhuysen, S.; Chiu, T.-G. A.; Scheffer, I. E.; Benfenati, F.; Maragliano, L.; Miceli, F.; Taglialatela, M.
10.1101/2024.05.20.593680 — biophysics — Posted on 2024-05-21
1504 Quantitative Assessment of Morphological Changes in Lipid Droplets and Lipid-Mito Interactions with Aging in Brown Adipose
Crabtree, A.; Neikirk, K.; Pinette, J.; Whiteside, A.; Shao, B.; McKenzie, J.; Vue, Z.; Vang, L.; Le, H.; Demirci, M.; Ahmad, T.; Owens, T. C.; Oliver, A.; Zeleke, F.; Beasley, H. K.; Garza-Lopez, E.; Scudese, E.; Koh, A.; Navarro, S.; Lam, J.; Kirk, B.; Mungai, M.; Sweetwyne, M. T.; Koh, H.-J.; Zaganjor, E.; Damo, S. M.; Gaddy, J. A.; Williams, C.; McReynolds, M.; Marshall, A. G.; Hinton, A.
10.1101/2023.09.23.559135 — biophysics — Posted on 2024-05-21
1508 Acarbose Impairs Gut Bacteroides Growth by Targeting Intracellular GH97 Enzymes
Koropatkin, N. M.; Brown, H. A.; Morris, A. L.; Pudlo, N. A.; Hopkins, A. E.; Martens, E.; Golob, J. L.
10.1101/2024.05.20.595031 — microbiology — Posted on 2024-05-21
1510 Novel cell-to-cell interactions revealed by cryotomography of a DPANN coculture system
Johnson, M. D.; Shepherd, D. C.; Sakai, H. D.; Mudaliyar, M.; Pandurangan, A. P.; Short, F. L.; Veith, P. D.; Scott, N.; Kurosawa, N.; Ghosal, D.
10.1101/2024.05.20.594898 — microbiology — Posted on 2024-05-21
1513 Bisphenol TMC disturbs mitochondrial activity and biogenesis, reducing lifespan and healthspan in the nematode Caenorhabditis elegans
Rathor, L.; Lee, H. J.; McElroy, T.; Beck, S.; Bailey, J. M.; Wohlgemuth, S.; Kim, S.; Heo, J. D.; Xiao, R.; Han, S. M.; Hyun, M.
10.1101/2024.05.20.595050 — pharmacology and toxicology — Posted on 2024-05-21
1515 π-PrimeNovo: An Accurate and Efficient Non-Autoregressive Deep Learning Model for De Novo Peptide Sequencing
Zhang, X.; Ling, T.; Jin, Z.; Xu, S.; Gao, Z.; Sun, B.; Qiu, Z.; Dong, N.; Wang, G.; Wang, G.; Li, L.; Abdul-Mageed, M.; Lakshmanan, L. V. S.; Ouyang, W.; Chang, C.; Sun, S.
10.1101/2024.05.17.594647 — bioinformatics — Posted on 2024-05-21
1519 Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation
Sperry, M. M.; Charrez, B.; Fotowat, H.; Gardner, E.; Pilobello, K.; Izadifar, Z.; Lin, T.; Kuelker, A.; Kaki, S.; Lewandowski, M.; Lightbown, S.; Martinez, R.; Marquez, S.; Moore, J.; Plaza-Oliver, M.; Sesay, A.; Shcherbina, K.; Sheehan, K.; Takeda, T.; Del Campo, D.; Andrijauskaite, K.; Cisneros, E.; Lopez, R.; Cano, I.; Maxwell, Z.; Jessop, I.; Veraza, R.; Bunegin, L.; Percival, T. J.; Weitzel, E.; Sleeter, J. J.; Parry, O. G.; Yracheta, J.; Pena, J. J.; Wood, D. M.; Homas, Z. T.; Hinshaw, C. J.; Cox-Hinshaw, J.; Levin, M.; Super, M.; Novak, R.; Ingber, D. E.
10.1101/2023.02.27.530270 — bioengineering — Posted on 2024-05-21
1520 Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis
Koller, T. O.; Burger, M. J.; Morici, M.; Paternoga, H.; Bulatov, T.; Di Stasi, A.; Dang, T.; Mainz, A.; Raulf, K.; Crowe-McAuliffe, C.; Scocchi, M.; Mardirossian, M.; Beckert, B.; Vazquez-Laslop, N.; Mankin, A.; Suessmuth, R. D.; Wilson, D. N.
10.1101/2024.05.21.595107 — biochemistry — Posted on 2024-05-21
1522 Comparison of spatial transcriptomics technologies across six cancer types
Cervilla, S.; Grases, D.; Perez, E.; Musulen, E.; Real, F. X.; Esteller, M.; Porta-Pardo, E.
10.1101/2024.05.21.593407 — genomics — Posted on 2024-05-21
1525 Production of four-gene (GTKO/hCD55/hTBM/hCD39)-edited donor pigs and kidney xenotransplantation
Yang, C.; Wei, Y.; Li, X.; Xu, K.; Huo, X.; Chen, G.; Zhao, H.; Wang, J.; Wei, T.; Qing, Y.; Guo, J.; Zhao, H.; Zhang, X.; Jiao, D.; Xiong, Z.; Jamal, M. A.; Zhao, H.-Y.; Wei, H.-J.
10.1101/2024.05.19.594896 — genetics — Posted on 2024-05-21
1526 Personality and MB-COMT gene: molecular-genetic and epigenetic associations with NEO-PI-R personality domains and facets in monozygotic twins
Mitrovic, D.; Smederevac, S.; Delgado-Cruzata, L.; Sadikovic, S.; Pajic, D.; Prinz, M.; Budimlija, Z.; Oljaca, M.; Kusic Tisma, J.; Vucinic, N.; Milutinovic, A.
10.1101/2024.05.20.594935 — genetics — Posted on 2024-05-21
1531 Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs
Zhang, K.; Manning, A.; Lentini, J. M.; Howard, J.; Dalwigk, F.; Maroofian, R.; Efthymiou, S.; Chan, P.; Eliseev, S.; Yang, Z.; Chang, H.; Karimiani, E. G.; Bakhshoodeh, B.; Houlden, H.; Kaiser, S. M.; Lowe, T. M.; Fu, D.
10.1101/2024.05.20.594868 — molecular biology — Posted on 2024-05-21
1533 The buoyancy of cryptococcal cells and its implications for transport and persistence of Cryptococcus in aqueous environments
Jimenez, I. A.; Stempinski, P. R.; Dragotakes, Q.; Greengo, S. D.; Sanchez Ramirez, L. R.; Casadevall, A.
10.1101/2024.05.20.595024 — microbiology — Posted on 2024-05-21
1534 The gatekeeper to gastric cancer; gastric microbiota invade the lamina propria in Helicobacter pylori-associated gastric carcinogenesis
Giddings, H. J.; Teodosio, A.; McMurray, J. L.; Hunter, K.; Abdawn, Z.; Cole, J. A.; Shannon-Lowe, C. D.; Rossiter-Pearson, A. E.
10.1101/2024.04.22.590522 — microbiology — Posted on 2024-05-21
1537 The human and mouse dendritic cell receptor DCIR binds to LRP1 N-glycans containing terminal galactoses, including the α-Gal antigen
Raymond, B. B. A.; Sneperger, T.; Rousset, S.; Gilles, N.; Bally, A.; Stella, A.; Hipgrave Ederveen, A. L.; Marcoux, J.; Trimaglio, G.; Thepaut, M.; Lagarrigue, F.; Burlet-Schiltz, O.; Wuhrer, M.; Fieschi, F.; Demange, P.; Neyrolles, O.; Rombouts, Y.
10.1101/2024.05.20.594848 — immunology — Posted on 2024-05-21
1538 Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during inflammation
Priestley, M. J.; Hains, A. K.; Mulholland, I. Z.; Spijkers-Shaw, S.; Zubkova, O. V.; Dyer, D. P.; Saunders, A. J.
10.1101/2024.05.21.595098 — immunology — Posted on 2024-05-21
1540 Sphingosine-1-phosphate signaling inhibition suppresses Th1-like Treg generation by reversing mitochondrial uncoupling
Coulombeau, R.; Selck, C.; Giang, N.; Al-Mohammad, A.; Ng, N.; Maher, A. K.; Arguello, R.; Scalfari, A.; Varley, J.; Nicholas, R.; Dominguez-Villar, M.
10.1101/2024.05.20.594966 — immunology — Posted on 2024-05-21
1542 The Observed T cell receptor Space database enables paired-chain repertoire mining, coherence analysis and language modelling
Raybould, M. I. J.; Greenshields-Watson, A.; Agarwal, P.; Aguilar-Sanjuan, B.; Olsen, T. H.; Turnbull, O. M.; Deane, C. M.
10.1101/2024.05.20.594960 — immunology — Posted on 2024-05-21
1544 Single-cell optogenetics reveals attenuation-by-suppression in visual cortical neurons
LaFosse, P. K.; Zhou, Z.; O'Rawe, J. F.; Friedman, N. G.; Scott, V. M.; Deng, Y.; Histed, M. H.
10.1101/2023.09.13.557650 — neuroscience — Posted on 2024-05-21
1545 Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism
Choi, A.; Smith, J.; Wang, Y.; Shin, H.; Kim, B.; Wiest, A.; Jin, X.; An, I.; Hong, J.; Antila, H.; Thomas, S.; Bhattarai, J. P.; Beier, K.; Ma, M.; Weber, F.; Chung, S.
10.1101/2023.12.26.573156 — neuroscience — Posted on 2024-05-21
1548 Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration
Wuennemann, F.; Sicklinger, F.; Bestak, K.; Nimo, J.; Thiemann, T.; Amrute, J. M.; Nordbeck, M.; Hartmann, N.; Ibarra-Arellano, M. A.; Tanevski, J.; Heine, C.; Frey, N.; Lavine, K.; Coscia, F.; Saez-Rodriguez, J.; Leuschner, F.; Schapiro, D.
10.1101/2024.05.20.594955 — systems biology — Posted on 2024-05-21
1550 Control of Physiologic Glucose Homeostasis via the Hypothalamic Modulation of Gluconeogenic Substrate Availability
Hashsham, A.; Kodur, N.; Su, J.; Tomlinson, A. J.; Yacawych, W. T.; Flak, J. N.; Lewis, K. T.; Oles, L. R.; Mori, H.; Bozadjieva-Kramer, N.; Turcu, A. F.; MacDougald, O. A.; Myers, M. G.; Affinati, A. H.
10.1101/2024.05.20.594873 — physiology — Posted on 2024-05-21
1552 A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice
Pernomian, L.; Waigi, E. W.; Nguyen, V.; Mohammed, A.; Costa, T. J.; Fontes, M. T.; Kubinak, J. L.; Aitken, A.; Biancardi, V. C.; Sinclair, D. A.; McCarthy, C. G.; Wang, Y.; Tan, W.; Wenceslau, C. F.
10.1101/2024.05.20.595057 — physiology — Posted on 2024-05-21
1556 Alasemenia, the earliest ovule with three wings and without cupule
Wang, D.; Yang, J.; Liu, L.; Zhou, Y.; Xu, P.; Qin, M.; Huang, P.
10.1101/2023.10.11.561822 — paleontology — Posted on 2024-05-21
1557 Automated Xeno-Free Chondrogenic Differentiation from Human Embryonic Stem Cells: Enhancing Efficiency and Ensuring High-Quality Mass Production
Chen, J.; Kataoka, O.; Tsuchiya, K.; Oishi, Y.; Takao, A.; Huang, Y.-C.; Komura, H.; Akiyama, S.; Itou, R.; Inui, M.; Enosawa, S.; Akutsu, H.; Komura, M.; Fuchimoto, Y.; UMEZAWA, A.
10.1101/2024.05.20.594905 — cell biology — Posted on 2024-05-21
1558 Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids
Shimonosono, M.; Morimoto, M.; Hirose, W.; Tomita, Y.; Matsuura, N.; Flashner, S.; Ebadi, M. S.; Okayasu, E. H.; Lee, C. Y.; Britton, W. R.; Martin, C.; Wuertz, B. R.; Parikh, A. S.; Sachdeva, U. M.; Ondrey, F. G.; Atigadda, V. R.; Elmets, C. A.; Abrams, J.; Muir, A. B.; Klein-Szanto, A. J.; Weinberg, K. I.; Momen-Heravi, F.; Nakagawa, H.
10.1101/2024.05.20.595023 — cell biology — Posted on 2024-05-21
1559 Redox-driven control of Yuh1/UCHL3 impacts mitochondrial health via NEDD8/Rub1 pathway
Issa, S.; Klein, Y.; Berda, E.; Harshuk-Shabso, D.; Sinha, A.; Sharaby, Y.; Benhar, M.; Pick, E.
10.1101/2024.05.20.594945 — cell biology — Posted on 2024-05-21
1560 Cigarette smoke impairs pulmonary vascular function through nAChR activation
Munar-Rubert, O.; Andreu-Martinez, R.; Rodriguez-Perez, J.; Lopez, N.; Barreira, B.; Fernandez-Malave, E.; Peces-Barba, G.; Munoz-Calleja, C.; Cogolludo-Torralba, A.; Calzada, M. J.
10.1101/2024.05.20.594977 — cell biology — Posted on 2024-05-21
1563 A Bioluminescent Assay for Quantification of Cellular Glycogen Levels
Leippe, D.; Choy, R.; Vidugiris, G.; Merritt, H.; Mellem, K. T.; Beattie, D. T.; Ullman, J. C.; Vidugiriene, J.
10.1101/2024.05.20.595028 — cell biology — Posted on 2024-05-21
1564 The insulin / IGF axis is critically important controlling gene transcription in the podocyte.
Hurcombe, J. A.; Dayalan, L.; Barrington, F.; Burdet, F.; Ni, L.; Coward, J. T.; Brinkkoetter, P.; Holzenberger, M.; Jeffries, A. R.; Oltean, S.; Welsh, G. I.; Coward, R. J.
10.1101/2024.05.20.594973 — cell biology — Posted on 2024-05-21
1565 Cerebellar control over inter-regional excitatory/inhibitory dynamics discriminates execution from observation of an action
Lorenzi, R. M.; Korkmaz, G.; Alahmadi, A. A. S.; Monteverdi, A.; Casiraghi, L.; D'Angelo, E.; Palesi, F.; Gandini Wheeler-Kingshott, C. A. M.
10.1101/2024.05.21.595114 — neuroscience — Posted on 2024-05-21
1569 Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment
Zhang, Y.; Xu, M.; Yuan, J.; Hu, Z.; Jiang, J.; Huang, J.; Wang, B.; Shen, J.; Long, M.; Fan, Y.; Montone, K. T.; Tanyi, J.; Tavana, O.; Chan, H. M.; Hu, X.; Zhang, L.
10.1101/2024.05.21.595159 — cancer biology — Posted on 2024-05-21
1572 Lymphostatin: Structure of a large multi-functional virulence factor
Griessmann, M.; Rasmussen, T.; Flegler, V. J.; Kraft, C.; Schneider, R.; Spantzel, L.; Stevens, M.; Borsch, M.; Bottcher, B.
10.1101/2024.05.21.595110 — biophysics — Posted on 2024-05-21
1577 3D-bioprinted patient-specific organotypic bone model mimicking mineralization dysregulation in FKBP10-related osteogenesis imperfecta
Griesbach, J. K.; de Leeuw, A. M.; Minacci, T.; Kodiyan, B.; Ndarugendamwo, T.; Lim, P. J.; Rohrbach, M.; Rubert, M.; Rueger, M.; Giunta, C.; Schulte, F. A.; Mueller, R.
10.1101/2024.05.20.594917 — bioengineering — Posted on 2024-05-21
1582 Endemic demographics of the Jomon people estimated based on complete mitogenomes reveal their regional diversity
Yoshida, K.; Wakiyama, Y.; Valverde, G.; Valverde, G.; Tanino, A.; Waku, D.; Katsumura, T.; Ogawa, M.; Nagaoka, T.; Hirata, K.; Koganebuchi, K.; Watanabe, Y.; Ohashi, J.; Yoneda, M.; Takahashi, R.; Oota, H.
10.1101/2024.05.16.594064 — genomics — Posted on 2024-05-21
1583 Maladaptation in cereal crop landraces following a soot-producing climate catastrophe
McLaughlin, C.; Shi, Y.; Viswanathan, V.; Leonard, L.; Sawers, R. J.; Kemanian, A.; Lasky, J. R.
10.1101/2024.05.18.594591 — evolutionary biology — Posted on 2024-05-21
1587 The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy
Mathavarajah, S.; Habib, E. B.; Kim, W. D.; Aoki, M. M.; Corkery, D. P.; Whelan, K. I. T.; Lukacs, J.; Salsman, J.; Huber, R. J.; Dellaire, G.
10.1101/2024.05.21.595022 — cell biology — Posted on 2024-05-21
1592 The Prefrontal Cortex to the Hippocampus Glutamatergic Pathway Regulates Reward Effects of Methamphetamine
Zhao, D.; Shi, W.; Li, M.; Xue, R.; Wang, H.; Zhang, L.; Huang, M.; Bai, L.; Gu, R.; Li, Y.; Zhang, X.; Kalivas, P.; Bai, J.
10.1101/2024.05.20.595065 — neuroscience — Posted on 2024-05-21
1594 Dynamic valuation bias explains social influence on cheating behavior
Benistant, J.; Guigon, V.; Nicolas, A.; Derrington, E.; Dreher, J.-C.
10.1101/2024.05.21.594859 — neuroscience — Posted on 2024-05-21
1596 Systemic migrations in enucleated cells
De la Fuente, I. M.; Carrasco-Pujante, J.; Camino-Pontes, B.; Fedetz, M.; Bringas, C.; Perez-Samartin, A.; Perez-Yarza, G.; Lopez, J. I.; Cortes, J.; Malaina, I.
10.1101/2024.05.19.594852 — systems biology — Posted on 2024-05-21
1597 Frequency and duration of sensory flicker controls astrocyte and neuron specific transcriptional profiles in 5xFAD mice
Bitarafan, S.; Pybus, A. F.; Rivera Moctezuma, F. G.; Adibi, M. H.; Franklin, T.; Singer, A. C.; Wood, L. B.
10.1101/2024.05.20.594705 — systems biology — Posted on 2024-05-21
1598 Cell surface RNA expression modulates alveolar epithelial function
Abledu, J. K.; Herbst, C. J.; Brandt, R.; Kocak, A.; Ghosh, P.; Lopez, J. L. G.; Diestelhorst, K.; Block, S.; Hackenberger, C.; Seitz, O.; Lopez-Rodriguez, E.; Ochs, M.; Kuebler, W. M.
10.1101/2024.05.19.594844 — physiology — Posted on 2024-05-21
1600 Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance
Liu, J.; He, Q.-L.; Zhou, J.; Chikarmane, R.; Hauk, G.; Rachakonda, A.; Vaghasia, A. M.; Castagna, N.; Steinberg, R. C.; Pham, M.-T.; Anders, N. M.; Wanjiku, T. M.; Nuhn, P.; Shim, J. S.; Giovinazzo, H.; Esopi, D. M.; Kim, K.; Coulter, J.; Wang, R.; Zhou, J.; Rudek, M. A.; Berger, J. M.; Liu, J. O.; Nelson, W. G.; Yegnasubramanian, S.
10.1101/2024.05.19.594134 — cancer biology — Posted on 2024-05-21
1601 Seclidemstat blocks the transcriptional function of multiple FET-fusion oncoproteins
Rask, G. C.; Taslim, C.; Bayanjargal, A.; Cannon, M. V.; Selich-Anderson, J.; Crow, J.; Duncan, A.; Theisen, E. R.
10.1101/2024.05.19.594897 — cancer biology — Posted on 2024-05-21
1602 Pro-survival roles for p21(Cip1/Waf1) in Non-Small Cell Lung Cancer
Cutty, S. J.; Hughes, F. A.; Ortega-Prieto, P.; Desai, S.; Thomas, P.; Fets, L. V.; Secrier, M.; Barr, A. R.
10.1101/2024.05.21.595102 — cancer biology — Posted on 2024-05-21
1603 ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC
Tran, N. L.; Jiang, J.; Ma, M.; Gadbois, G. E.; Gulay, K. C. M.; Verano, A.; Zhou, H.; Huang, C.-T.; Scott, D. A.; Bang, A. G.; Tiriac, H.; Lowy, A. M.; Wang, E. S.; Ferguson, F. M.
10.1101/2024.05.19.594824 — cancer biology — Posted on 2024-05-21
1605 Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX
Vaskevicius, A.; Baronas, D.; Leitans, J.; Kvietkauskaite, A.; Ruksenaite, A.; Manakova, E.; Toleikis, Z.; Kaupinis, A.; Kazaks, A.; Gedgaudas, M.; Mickeviciute, A.; Juozapaitiene, V.; Schioth, H.; Jaudzems, K.; Valius, M.; Tars, K.; Grazulis, S.; Meyer-Almes, F.-J.; Matuliene, J.; Zubriene, A.; Dudutiene, V.; Matulis, D.
10.1101/2024.05.20.594908 — biophysics — Posted on 2024-05-21
1615 Genome assembly and annotation of the red flour beetle (Tribolium castaneum) from India
Singhal, S.; Choudhary, C.; Basu, D. N.; Seal, S.; Khan, I.; Shukla, J. N.; Agashe, D.
10.1101/2024.05.20.594914 — genomics — Posted on 2024-05-21
1617 The long-term effects of chemotherapy on normal blood cells
Mitchell, E.; Pham, M. H.; Clay, A.; Sanghvi, R.; Pietsch, S.; Hsu, J. I.; Jung, H.; Vedi, A.; Moody, S.; Wang, J.; Leonganmornlert, D.; Spencer Chapman, M.; Williams, N.; Dunstone, E.; Santarsieri, A.; Cagan, A.; Machado, H. E.; Baxter, J.; Follows, G.; Hodson, D. J.; McDermott, U.; Docherty, G. J.; Martincorena, I.; Humphreys, L.; Mahbubani, K.; Saeb Parsy, K.; Takahashi, K.; Goodell, M. A.; Kent, D.; Laurenti, E.; Campbell, P. J.; Rahbari, R.; Nanglia, J.; Stratton, M. R.
10.1101/2024.05.20.594942 — cell biology — Posted on 2024-05-21
1620 Transcriptional control of central T cell tolerance by NR4A family nuclear receptors
Nielsen, H. V.; Mueller, J. L.; Hiwa, R.; Yang, L.; Proekt, I.; Rackaityte, E.; Aylard, D.; Scharer, C. D.; Anderson, M.; Au-Yeung, B. B.; Zikherman, J.
10.1101/2024.05.19.594881 — immunology — Posted on 2024-05-21
1624 Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.
Zhu, Y.; Yao, L.; Gallo-Ferraz, A. L.; Bombassaro, B.; Simoes, M. R.; Abe, I.; Chen, J.; Sarker, G.; Ciccarelli, A.; Zhou, L.; Lee, C.; Martinez-Sanchez, N.; Dustin, M.; Anderson, K.; Zhan, C.; Horvath, T.; Velloso, L.; Kajimura, S.; Domingos, A. I.
10.1101/2024.05.18.594804 — physiology — Posted on 2024-05-21
1625 Biomarker Identification by Proteomic Analysis of Vitreous Humor and Plasma in Diabetic Retinopathy
Huang, Q.; Banks, A.; Stacy, R.; Li, N.; Kim, Y.; Jennings, L.; Finkel, N.; Yao, S.; Wu, A.; Chen, A.; Obeidat, M.; Grosskreutz, C.; Liew, S. H. M.; Prasanna, G.; Yu, H. G.; Loureiro, J.; Zhang, Q.
10.1101/2024.05.18.594835 — physiology — Posted on 2024-05-21
1629 epiTCR-KDA: Knowledge Distillation model on Dihedral Angles for TCR-peptide prediction
Pham, M.-D. N.; Su, C. T.-T.; Nguyen, T.-N.; Nguyen, H.-N.; Nguyen, D. D. A.; Giang, H.; Nguyen, D.-T.; Phan, M.-D.; Nguyen, V.
10.1101/2024.05.18.594806 — bioinformatics — Posted on 2024-05-21
1633 Genomic Signatures of Microgeographic Adaptation in Anopheles coluzzii Along an Anthropogenic Gradient in Gabon
Daron, J.; Bouafou, L.; Tennessen, J.; Rahola, N.; Makanga, B.; Akone-Ella, O.; Ngangue, M.; Longo Pendy, N.; Paupy, C.; Neafsey, D. E.; Fontaine, M. C.; Ayala, D.
10.1101/2024.05.16.594472 — evolutionary biology — Posted on 2024-05-21
1635 Developmental stage and level of submersion in water impact the viability of lone star and winter tick eggs during flooding
Alhawsawi, M. R. I.; Lewis, D. A.; Frigard, R. A.; Smith, E. M.; Sivakumar, J.; Sharma, A. M.; Nantz, A. R.; Sabile, C.; Kennedy, J.; Loni, R.; LeFefevre, G.; Vaka, A.; Leanza, Q.; Kelley, M.; Stacey, C. L.; Santosh, R. A.; Catlett, N.; Cady, T. L.; Rizvi, R. S.; Wagner, Z.; Olafson, P. U.; Benoit, J. B.
10.1101/2024.05.18.594128 — ecology — Posted on 2024-05-21
1636 Harmonising distributed tree inventory datasets across India can fill critical gaps in tropical ecology
Anujan, K.; Mohanbabu, N.; Gopal, A.; Surendra, A.; Krishnan, A.; Jayanth, A.; Nair, T.; Ongole, S.; Sankaran, M.
10.1101/2024.05.18.594774 — ecology — Posted on 2024-05-21
1638 Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid
Fita-Torro, J.; Garrido-Huarte, J. L.; Michel, A. H.; Kornmann, B.; Pascual-Ahuir, A.; Proft, M.
10.1101/2023.11.06.565743 — molecular biology — Posted on 2024-05-21
1640 T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cells
Garnica, J.; Sole, P.; Yamanouchi, J.; Moro, J.; Mondal, D.; Fandos, C.; Serra, P.; Santamaria, P.
10.1101/2024.05.17.594762 — immunology — Posted on 2024-05-21
1644 Characterization of a major QTL for sodium accumulation in tomato shoot
Hereil, A.; Guillaume, M.; Duboscq, R.; Carretero, Y.; Pelpoir, E.; Bitton, F.; Giraud, C.; Karlova, R.; Testerink, C.; Stevens, R.; Causse, M.
10.1101/2024.05.21.595121 — plant biology — Posted on 2024-05-21
1645 A Sap Peptide Conserved across Flowering Plants Positively Regulates Lignin Biosynthesis, Biomass and Immunity
Chen, C.-H.; Liou, P.-C.; Hsu, Y.-F.; Wang, I.-F.; Kuo, C.-Y.; Huang, K.-H.; Yu, J.-H.; Chen, C.-W.; Wu, C.-C.; Lin, D.-G.; Li, C.-B.; Tu, Y.-K.; Hsu, C.-C.; Su, J.-C.; Xia, K.; Tsai, I. J.; Lin, Y.-C. J.; Chen, Y.-L.
10.1101/2024.05.20.594799 — plant biology — Posted on 2024-05-21
1646 Parallel Evolution of Salinity Tolerance in Arabidopsis thaliana Accessions from Cape Verde Islands
Martinez Rivas, F. J.; Wozny, D.; Xue, Z.; Gilbault, E.; Sapir, T.; Rouille, M.; Ricou, A.; Medina, J.; NOEL, L. D.; Lauber, E.; Voxeur, A.; Loudet, O.; Clement, G.; Jimenez-Gomez, J. M.
10.1101/2024.05.21.595092 — plant biology — Posted on 2024-05-21
1647 De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancer
Zhang, H.; Yu, Q.; Santana-Codina, N.; Poupault, C.; Campos, C.; Qin, X.; Padhye, A.; Sindoni, N.; Kuljanin, M.; Wang, J.; Dorman, M. J.; Aguirre, A. J.; Dougan, S. K.; Sarosiek, K. A.; Mancias, J. D.
10.1101/2024.05.17.594738 — cancer biology — Posted on 2024-05-21
1650 Accuracy of dipole source reconstruction in the 3-layerBEM model against the 5-layer BEM-FMM model
Nunez Ponasso, G. C.; McSweeney, R. C.; Wartman, W. A.; Lai, P.; Haueisen, J.; Maess, B.; Knosche, T.; Weise, K.; Noetscher, G.; Raij, T.; Makaroff, S. N.
10.1101/2024.05.17.594750 — bioinformatics — Posted on 2024-05-21
1654 Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning
Gherman, I. M.; Rees-Garbutt, J. P.; Pang, W.; Abdallah, Z. S.; Gorochowski, T. E.; Grierson, C. S.; Marucci, L.
10.1101/2023.10.30.564402 — bioengineering — Posted on 2024-05-21
1655 MSA: scalable DNA methylation screening BeadChip for high-throughput trait association studies
Goldberg, D. C.; Cloud, C.; Lee, S. M.; Barnes, B.; Gruber, S.; Kim, E.; Pottekat, A.; Westphal, M.; McAuliffe, L.; Majournie, E.; KalayilManian, M.; Zhu, Q.; Tran, C.; Hansen, M.; Parker, J. B.; Kohli, R. M.; Porecha, R.; Renke, N.; Zhou, W.
10.1101/2024.05.17.594606 — genomics — Posted on 2024-05-21
1656 The impact of ancestral, environmental and genetic influences on germline de novo mutation rates and spectra
Garcia-Salinas, O. I.; Hwang, S.; Huang, Q. Q.; Kapanis, J.; Neville, M. D.; Sanghvi, R.; Day, F.; Rahbari, R.; Scally, A.; Martin, H. C.
10.1101/2024.05.17.594464 — genetics — Posted on 2024-05-21
1658 Accelerating Genome- and Phenome-Wide Association Studies using GPUs - A case study using data from the Million Veteran Program
Rodriguez, A. A.; Kim, Y.; Nandi, T. N.; Keat, K.; Bhukar, R.; Conery, M.; Liu, M.; Hessington, J.; Begoli, E.; Tourassi, G.; Muralidhar, S.; Natarajan, P.; Voight, B. F.; Cho, K.; Gaziano, M. J.; Damrauer, S.; Liao, K. P.; Zhou, W.; Huffman, J. E.; Verma, A.; Madduri, R. K.
10.1101/2024.05.17.594583 — genetics — Posted on 2024-05-21
1661 Phylogenomics reveals an island as a genetic reservoir of a continental population
Aoki, D.; Senzaki, M.; Ando, H.; Odaya, Y.; Heim, W.; Kitazawa, M.; Tom, W.; Trense, D.; Bastardot, M.; Fukuda, A.; Takahashi, M.; Kondo, N.
10.1101/2023.09.27.559751 — evolutionary biology — Posted on 2024-05-21
1664 Maternal Western-style diet programs skeletal muscle gene expression in lean adolescent Japanese macaque offspring
Beck, E. A.; Hetrick, B.; Nassar, L.; Turnball, D. W.; Dean, T. A.; Gannon, M.; Aagaard, K. M.; Wesolowski, S. R.; Friedman, J. E.; Kievit, P.; McCurdy, C. E.
10.1101/2024.05.17.594191 — physiology — Posted on 2024-05-21
1666 Carbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome
Malbon, A. J.; Czopek, A.; Beekman, A. M.; Goddard, Z. R.; Boyle, A.; Ivy, J.; Stewart, K.; Denham, S.; Simpson, J. P.; Homer, N. Z.; Walker, B. R.; Dhaun, N.; Bailey, M. A.; Morgan, R.
10.1101/2024.05.17.594787 — physiology — Posted on 2024-05-21
1668 The CALERIE™ Genomic Data Resource
Ryan, C. P.; Corcoran, D. L.; Banskota, N.; Eckstein Indik, C.; Floratos, A.; Friedman, R. A.; Kobor, M. S.; Kraus, V. B.; Kraus, W.; MacIsaac, J.; Orenduff, M.; Pieper, C. F.; White, J.; Ferrucci, L.; Horvath, S.; Huffman, K. M.; Belsky, D. W.
10.1101/2024.05.17.594714 — genomics — Posted on 2024-05-21
1670 Cholestasis alters polarization and suppressor function of hepatic regulatory T cells.
Kudira, R.; Yang, Z. F.; Osuji, I.; Karns, R.; Bariya, P.; Pfuhler, L.; Mullen, M.; Taylor, A.; Ji, H.; Lages, C. S.; Yang vom Hofe, A.; Shi, T.; Pasula, S.; Wayman, J. A.; Bernieh, A.; Zhang, W.; Chougnet, C. A.; Hildeman, D.; Tiao, G. M.; Huppert, S. S.; Subramanian, S.; Salomonis, N.; Miraldi, E.; Miethke, A. G.
10.1101/2024.05.17.594680 — immunology — Posted on 2024-05-21
1671 Disruptors of sestrin-MAPK interactions rejuvenate T cells and expand TCR specificity
Lanna, A.; D'Ambra, C.; Rinaldi, F.; Chocarro De Erauso, L.; Delpero, M.; Capitani, M.; Karin, M.
10.1101/2024.05.17.594698 — immunology — Posted on 2024-05-21
1675 The Novel Chimeric Multi-Agonist Peptide (GEP44) Reduces Energy Intake and Body Weight in Male and Female Diet-Induced Obese Mice in a Glucagon-Like Peptide-1 Receptor-Dependent Manner
Blevins, J. E.; Honeycutt, M. K.; Slattery, J. D.; Matvey, M.; Rambousek, J. R.; Edison, E.; Dodson, A. D.; Shelton, K. A.; Salemeh, T. S.; Elfers, C. T.; Chichura, K. S.; Ashlaw, E. F.; Zraika, S.; Doyle, R. P.; Roth, C. L.
10.1101/2024.05.17.594690 — pharmacology and toxicology — Posted on 2024-05-21
1677 Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors
Udumula, M. P.; Rashid, F.; Singh, H.; Pardee, T.; Luther, S.; Bhardwaj, T.; Anjaly, K.; Piloni, S.; Hijaz, M.; Gogoi, R.; Philip, P. A.; Munkarah, A.; Giri, s.; Rattan, R.
10.1101/2024.05.16.594585 — cancer biology — Posted on 2024-05-21
1679 LncCE: Landscape of Cellular-Elevated LncRNAs in Single Cells Across Normal and Cancer Tissues
Xu, K.; Liu, Y.; Lv, C.; Luo, Y.; Shi, J.; Zou, H.; Zhou, W.; Lv, D.; Yang, C.; Li, Y.; Xu, J.
10.1101/2024.05.17.594684 — cancer biology — Posted on 2024-05-21
1681 Accounting for digestion enzyme bias in Casanovo
Melendez, C.; Sanders, J.; Yilmaz, M.; Bittremieux, W.; Fondrie, W.; Oh, S.; Noble, W. S.
10.1101/2024.05.16.594602 — bioinformatics — Posted on 2024-05-21
1682 Spatial cell graph analysis reveals skin tissue organization characteristic for cutaneous T cell lymphoma
Sarkar, S.; Moller, A.; Hartebrodt, A.; Erdmann, M.; Ostalecki, C.; Baur, A.; Blumenthal, D. B.
10.1101/2024.05.17.594629 — bioinformatics — Posted on 2024-05-21
1683 Coarse-graining the recognition of a glycolipid by the C-type lectin Mincle receptor
Noriega, M.; Corey, R. A.; Haanappel, E.; Demange, P.; Czaplicki, G.; Atkinson, R. A.; Chavent, M.
10.1101/2024.05.17.594645 — bioinformatics — Posted on 2024-05-21
1684 A Novel Gene ARHGAP44 for Longitudinal Changes in Glycated Hemoglobin (HbA1c) in Subjects without Type 2 Diabetes: Evidence from the Long Life Family Study (LLFS) and the Framingham Offspring Study (FOS)
Wang, S.; Lenzini, P.; Thygarajan, B.; Lee, J. H.; Vardarajan, B. N.; Yashin, A.; Miljkovic, I.; Daw, E. W.; Lin, S. J.; Patti, G.; Brent, M.; Zmuda, J. M.; Perls, T. T.; Christensen, K.; Province, M. A.; An, P.
10.1101/2024.05.16.594575 — genetics — Posted on 2024-05-21
1685 iLipidome: enhancing statistical power and interpretability using hidden biosynthetic interdependencies in the lipidome
Lin, W.-J.; CHIANG, A. W. T.; Zhou, E. H.; Liang, C.; Liu, C.-H.; Ma, W.-L.; Cheng, W.-C.; Lewis, N. E.
10.1101/2024.05.16.594607 — systems biology — Posted on 2024-05-21
1692 A Mechanically Resilient Soft Hydrogel Improves Drug Delivery for Treating Post-Traumatic Osteoarthritis in Physically Active Joints
Joshi, N.; Yan, J.; Dang, M.; Slaughter, K.; Wang, Y.; Wu, D.; Ung, T.; Pandya, V.; Chen, M. X.; Kaur, S.; Bhagchandani, S.; Alfassam, H.; Joseph, J.; Gao, J.; Dewani, M.; Yip, R. C. S.; Weldon, E.; Shah, P.; Shukla, C.; Sherman, N.; Luo, J. N.; Conway, T.; Elickhoff, J. P.; Botelho, L.; Alhasan, A.; Karp, J.; Ermann, J.
10.1101/2024.05.16.594611 — bioengineering — Posted on 2024-05-21
1693 IL-23 drives uveitis by acting on a novel population of tissue-resident entheseal T cells
Hedley, R.; Ward, A.; Chu, C. J.; Coupland, S. E.; Kiriakidis, S.; Taylor, P. C.; Dakin, S. G.; Buckley, C. D.; Sherlock, J.; Dick, A. D.; Copland, D. A.
10.1101/2024.05.16.594586 — immunology — Posted on 2024-05-21
1695 Unraveling the impact of hyperleptinemia on female reproduction: Insights from transgenic pig model
Jamal, M. A.; Cheng, Y.; Jiao, D.; Cheng, W.; Zou, D.; Wang, X.; Wei, T.; Guo, J.; Xu, K.; Zhao, H.; Pu, S.; Yang, C.; Qing, Y.; Jia, B.; Li, H.; Zhao, R.; Zhao, H.-Y.; Wei, H.-J.
10.1101/2024.05.20.595055 — genetics — Posted on 2024-05-20
1698 A PARP2-specific active site alpha-helix melts to permit DNA damage-induced enzymatic activation
Smith-Pillet, E. S.; Billur, R.; Langelier, M.-F.; Talele, T. T.; Pascal, J. M.; Black, B. E.
10.1101/2024.05.20.594972 — biochemistry — Posted on 2024-05-20
1699 rpfF is not required for X. translucens pv. undulosa pathogenesis
Heiden, N.; Butchacas, J.; Klass, T.; Cohen, S. P.; Roman-Reyna, V.; Merfa, M. V.; Valero David, G. E.; Vargas-Garcia, C.; Olmos, C.; Velez-Negron, Y.; Lewandowski, M. M.; Jacobs, J. M.
10.1101/2024.05.20.594922 — molecular biology — Posted on 2024-05-20
1700 MECOM promotes leukemia progression and inhibits mast cell differentiation through functional competition with GATA2
Iida, K.; Nakanishi, M.; Nakahara, J.; Asada, S.; Isobe, T.; Yabushita, T.; Ozawa, M.; Yamada, Y.; Kitamura, T.; Yamamoto, K.; Goyama, S.
10.1101/2024.05.20.594903 — molecular biology — Posted on 2024-05-20
1702 Pangenomic analysis of Helcococcus ovis reveals widespread tetracycline resistance and a novel bacterial species, Helcococcus bovis.
Cunha, F.; Zhai, Y.; Casaro, S.; Jones, K. L.; Hernandez, M.; Bisinotto, R. S.; Kariyawasam, S.; Brown, M. B.; Phillips, A.; Jeong, K. C.; Galvao, K. N.
10.1101/2024.05.20.594939 — microbiology — Posted on 2024-05-20
1705 A recombinant CHIKV-NLuc virus identifies chondrocytes as target of Chikungunya virus in a immunocompetent mouse model
Legros, V.; Belarbi, E.; Jeannin, p.; Kuemmerer, B.; Hardy, D.; Despres, P.; Gessain, A.; Roques, P.; Ceccaldi, P.-E.; Choumet, V.
10.1101/2024.05.20.594924 — microbiology — Posted on 2024-05-20
1708 High-density CRISPRi screens reveal adaptive transcriptional gradients in cyanobacteria
Hren, A.; Lollini, N.; Carper, D. L.; Abraham, P. E.; Cameron, J. C.; Fox, J. M.; Eckert, C.
10.1101/2024.05.20.595006 — microbiology — Posted on 2024-05-20
1712 Polar flagellin glycan metaheterogeneity of Aeromonas hydrophila strain ATCC 7966T
Fulton, K. M.; Mendoza-Barbera, E.; Tomas, J. M.; Twine, S. M.; Smith, J. C.; Merino, S.
10.1101/2024.05.20.594992 — biochemistry — Posted on 2024-05-20
1713 Isoform-specific N-linked glycosylation of voltage-gated sodium channel alpha-subunits alters beta-subunit binding sites
Beaudoin, C. A.; Kohli, M.; Salvage, S. C.; Liu, H.; Arundel, S. J.; Hamaia, S. W.; Lei, M.; Huang, C. L.- H.; Jackson, A. P.
10.1101/2024.05.20.594950 — biochemistry — Posted on 2024-05-20
1714 Production and functional verification of 8-gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-edited donor pigs for xenotransplantation
Wang, J.; Xu, K.; Liu, T.; Zhao, H.; Jamal, M. A.; Chen, G.; Huo, X.; Yang, C.; Jiao, D.; Wei, T.; Huang, H.; Zhao, H.; Guo, J.; Wang, F.; Zhang, X.; Liu, K.; Qu, S.; Wang, G.; Zhao, H.-Y.; Zeng, Z.; Wei, H.-J.
10.1101/2024.05.19.594889 — genetics — Posted on 2024-05-20
1715 Endogenous opioid dynamics in the dorsal striatum sculpt neural activity to control goal-directed action
Gowrishankar, R.; Hjort, M.; Elerding, A. J.; Shirley, S.; Van Tilburg, J.; Marcus, D. J.; Abrera, K. A.; Senthilkumar, P.; Sumarli, D.; Motovilov, K.; Lau, V.; Gordon-Fennell, A. A.; Zhou, Z. C.; Dong, C.; Tian, L.; Stuber, G. D.; Bruchas, M. R.
10.1101/2024.05.20.595035 — neuroscience — Posted on 2024-05-20
1716 Kif1a and intact microtubules maintain synaptic-vesicle populations at ribbon synapses in zebrafish hair cells
David, S.; Pinter, K.; Nguyen, K.-K.; Lee, D. S.; Lei, Z.; Sokolova, Y.; Sheets, L.; Kindt, K. S.
10.1101/2024.05.20.595037 — neuroscience — Posted on 2024-05-20
1717 Human birth tissue products as a regenerative medicine to inhibit post-surgical pain through multi-modal action
Zhang, C.; Huang, Q.; Ford, N. C.; Limjunyawong, N.; Lin, Q.; Yang, F.; Cui, X.; Uniyal, A.; Liu, J.; Mahabole, M.; He, H.; Wang, X.; Duff, I.; Wang, Y.; Wan, J.; Zhu, G.; Raja, S. N.; Jia, H.; Yang, D.; Dong, X.; Tseng, S.; He, S.; Guan, Y.
10.1101/2024.05.19.594874 — neuroscience — Posted on 2024-05-20
1719 Neuraminidase 1 regulates the cellular state of microglia by modulating the sialylation of Trem2
Fremuth, L. E.; Hu, H.; van de Vlekkert, D.; Annunziata, I.; Weesner, J. A.; Gomero, E.; d'Azzo, A.
10.1101/2024.05.20.595036 — neuroscience — Posted on 2024-05-20
1721 Hippocampal neuroinflammation causes sex-specific disruptions in instrumental conditioning, Pavlovian approach, and neuronal excitation
Ganesan, K.; Ghorbanpour, S.; Kendall, W.; Broome, S. T.; Gladding, J. M.; Dhungana, A.; Abiero, A. R.; Mahmoudi, M.; Castorina, A.; Kendig, M. D.; Becchi, S.; Valova, V.; Cole, L.; Bradfield, L. A.
10.1101/2024.05.19.594460 — animal behavior and cognition — Posted on 2024-05-20
1726 Canonical neurodevelopmental trajectories of structural and functional manifolds
Monaghan, A.; Bethelehem, R. A. I.; Akarca, D.; Margulies, D.; the CALM Team, ; Astle, D. S.
10.1101/2024.05.20.594657 — neuroscience — Posted on 2024-05-20
1729 Signatures of social pain empathy: general and process-specific brain-wide representations of social exclusion and separation
Zhang, X.; Qing, P.; Liu, Q.; Liu, C.; Liu, L.; Gan, X.; Fu, K.; Lan, C.; Zhou, X.; Kendrick, K. M.; Becker, B.; Zhao, W.
10.1101/2024.05.19.594630 — neuroscience — Posted on 2024-05-20
1730 GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory
Kim, J.-H.; Kim, H. J.; Lee, S.; Kim, G. H.; Sung, K.; Yoo, T.; Pyo, J. H.; Jo, H.-j.; Lee, S.; Lee, H.-Y.; Jung, J. H.; Lee, K. J.
10.1101/2024.05.19.594887 — neuroscience — Posted on 2024-05-20
1732 L-Dopa incorporation into tubulin alters microtubule dynamics and reduces dendritic spine invasion and synapse maintenance
Zorgniotti, A.; Sharma, A.; Ramirez-Rios, S.; Sanyal, C.; Aleman, M.; Ditamo, Y.; Moutin, M.-J.; Bisig, G.; Peris, L.
10.1101/2024.05.20.595021 — neuroscience — Posted on 2024-05-20
1737 A Human iPSC-derived Organoid System to Model Myelin Destruction and Repair
Ramesan, S.; Mason, J.; Swanson, M. E. V.; Mills, S.; Turner, B. J.; Rutar, M.; Gonsalvez, D. G.; Barton, S. K.
10.1101/2024.05.19.594912 — neuroscience — Posted on 2024-05-20
1741 Direct detection of 8-oxo-dG using nanopore sequencing
Pages-Gallego, M.; van Soest, D. M. K.; Besselink, N. J. M.; Straver, R.; Keijer, J. P.; Vermeulen, C.; Marcozzi, A.; van Roosmalen, M. J.; van Boxtel, R.; Burgering, B. M. T.; Dansen, T. B.; de Ridder, J.
10.1101/2024.05.17.594638 — bioinformatics — Posted on 2024-05-20
1743 Context-dependent neural preparation for information relevance vs. probability
Penalver, J. M. G.; Gonzalez-Garcia, C.; Palenciano, A. F.; Lopez-Garcia, D.; Ruz, M.
10.1101/2024.05.20.594985 — neuroscience — Posted on 2024-05-20
1744 Projections from thalamic nucleus reuniens to medial septum enable extinction of remote fear memory
Tomaszewski, K. F.; Ziolkowska, M.; Lukasiewicz, K.; Caly, A.; Sotoudeh, N.; Puchalska, M.; Salamian, A.; Radwanska, K.
10.1101/2024.05.20.594930 — neuroscience — Posted on 2024-05-20
1745 Beyond the phloem: A general role of the Arabidopsis OCTOPUS gene family in controlling plant growth vigour
Crivelli, S.; Bartusch, K.; Ruiz-Sola, M. A.; Coiro, M.; Schmidt Kjolner Hansen, S.; Truernit, E.
10.1101/2024.05.17.594124 — plant biology — Posted on 2024-05-20
1747 Protein Structure Inspired Drug Discovery
Qiao, F.; Binkowski, A.; Broughan, I.; Chen, W.; Natarajan, A.; Schiltz, G.; Scheidt, K.; Anderson, W.; Bergan, R.
10.1101/2024.05.17.594634 — cancer biology — Posted on 2024-05-20
1749 Pi-PrimeNovo: An Accurate and Efficient Non-Autoregressive Deep Learning Model for De Novo Peptide Sequencing
Zhang, X.; Ling, T.; Jin, Z.; Xu, S.; Gao, Z.; Sun, B.; Qiu, Z.; Dong, N.; Wang, G.; Wang, G.; Li, L.; Mageed, M. A.; Lakshmanan, L. V. S.; Ouyang, W.; Chang, C.; Sun, S.
10.1101/2024.05.17.594647 — bioinformatics — Posted on 2024-05-20
1750 Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50
Paz, E.; Jain, S.; Gottfried, I.; Staretz-Chacham, O.; Mahajnah, M.; Bagchi, P.; Seyfried, N.; Ashery, U.; Azem, A.
10.1101/2024.05.20.594480 — biochemistry — Posted on 2024-05-20
1751 Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome
Ganesan, S.; Murray, R. M.; Sotelo, J.; Eton, E. O.; Takashima, K.; Botella, T.; Beattie, K.; Indart, A. C.; Chraiki, N.; Croizier, C.; Izzo, F.; Potenski, C.; Marro, S.; Wu, Z.; Gao, S.; Young, N. S.; Blair, J. D.; Satija, R.; Terrier, B.; Heiblig, M.; Papapetrou, E. P.; Sujobert, P.; Kosmider, O.; Beck, D. B.; Landau, D. A.
10.1101/2024.05.19.594376 — genomics — Posted on 2024-05-20
1752 RoCK and ROI: Single-cell transcriptomics with multiplexed enrichment of selected transcripts and region-specific sequencing
Moro, G.; Mallona, I.; Maillard, J.; Brugger, M. D.; Fazilaty, H.; Szabo, Q.; Valenta, T.; Handler, K.; Kerlin, F.; Moor, A. E.; Zinzen, R.; Robinson, M. D.; Brunner, E.; Basler, K.
10.1101/2024.05.18.594120 — genomics — Posted on 2024-05-20
1753 Long somatic DNA-repeat expansion drives neurodegeneration in Huntington disease
Handsaker, R. E.; Kashin, S.; Reed, N. M.; Tan, S.; Lee, W.-S.; McDonald, T. M.; Morris, K.; Kamitaki, N.; Mullally, C. D.; Morakabati, N.; Goldman, M.; Lind, G.; Kohli, R.; Lawton, E.; Hogan, M.; Ichihara, K.; Berretta, S.; McCarroll, S. A.
10.1101/2024.05.17.592722 — genetics — Posted on 2024-05-20
1754 Ancient genomics reveals a genetic continuum with dual structure in the Classic Copan
Murray, M.; Nakamura, S.; Fuentes, M.; Ogawa, M.; Cassidy, L. M.; Gakuhari, T.; Nakagome, S.
10.1101/2024.05.17.594672 — evolutionary biology — Posted on 2024-05-20
1755 Evaluating genomic offset predictions in a forest tree with high population genetic structure
Archambeau, J.; Benito Garzon, M.; de-Miguel, M.; Changenet, A.; Bagnoli, F.; Barraquand, F.; Marchi, M.; Vendramin, G.; Cavers, S.; Perry, A.; Gonzalez-Martinez, S. C.
10.1101/2024.05.17.594631 — evolutionary biology — Posted on 2024-05-20
1756 Competitor Displacement by an Herbivore that Manipulates Plant Defences
Chafi, R.; Ataide, L.; Scala, A.; Villacis-Perez, E.; Alba Cano, J.; Schimmel, B. C. J.; Kant, M.
10.1101/2024.05.20.594407 — ecology — Posted on 2024-05-20
1758 SARS-CoV-2 variants from long-term, persistently infected immunocompromised patients have altered syncytia formation, temperature-dependent replication, and serum neutralizing antibody escape
Wouters, C.; Sachithanandham, J.; Akin, E.; Pieterse, L.; Fall, A.; Truong, T. T.; Bard, J. D.; Yee, R.; Sullivan, D. J.; Mostafa, H. H.; Pekosz, A.
10.1101/2024.05.18.594818 — microbiology — Posted on 2024-05-20
1759 Experimental myositis: an optimised version of C-protein-induced myositis
GIANNINI, M.; Rovito, D.; Oulad-Abdelghani, M.; Messaddeq, N.; Debrut, L.; KESSLER, P.; Charles, A. L.; GENY, B.; Metzger, D.; Laverny, G.; Meyer, A.
10.1101/2024.05.18.593723 — immunology — Posted on 2024-05-20
1760 HIV-1 infection is associated with depletion of germinal center B cells and a decrease in IgA+ plasma cells in the GI tract
Cossarini, F.; Shang, J.; Krek, A.; Al-taie, Z.; Hou, R.; Canales-Herrerias, P.; Tokuyama, M.; Tankelevich, M.; Tillowiz, A.; Jha, D.; Livanos, A.; Leyre, L.; Uzzan, M.; Martinez-Delgado, G.; Taylor, M.; Sharma, K.; Bourgonje, A. R.; Cruz, M.; Ioannou, G.; Dawson, T.; D'souza, D.; Kim-Schulze, S.; Ahmed, A.; Aberg, J. A.; Chen, B. K.; Gnjatic, S.; Polydorides, A. D.; Cerutti, A.; Argmann, C.; Vujkovic-Cvijin, I.; Suarez-Farinas, M.; Petralia, F.; Faith, J. J.; Mehandru, S.
10.1101/2024.05.17.590425 — immunology — Posted on 2024-05-20
1761 Genome sequencing of 'Fuji' apple clonal varieties reveals evolutionary history and genetic mechanism of the spur-type morphology
Cai, Y.; Gao, X.; Mao, J.; Liu, Y.; Tong, L.; Chen, X.; Liu, Y.; Kou, W.; Chang, C.; Foster, T.; Yao, J.; Cornille, A.; Tahir, M. M.; Liu, Z.; Yan, Z.; Lin, S.; Ma, F.; Ma, J.; Xing, L.; An, N.; Zuo, X.; Lv, Y.; Zhao, Z.; Li, W.; Li, Q.; Zhao, C.; Hu, Y.; Liu, H.; Wang, C.; Shi, X.; Ma, D.; Fei, Z.; Jiang, Y.; Zhang, D.
10.1101/2024.05.16.594617 — plant biology — Posted on 2024-05-20
1762 Proteomic analysis to classify extracellular vesicles and plasmodesmata in Arabidopsis cell culture supernatants
Takei, T.; Asou, T.; Hamakawa, N.; Noguchi, R.; Sumiyoshi, K.; Sueyoshi, K.; Imami, K.; Hamada, T.
10.1101/2024.05.17.594688 — plant biology — Posted on 2024-05-20
1763 Emergence of potato virus Y outbreaks in tomatoes in Brazil, the disease and spread
Lucena, V. S.; Nakasu, E. Y. T.; Pereira, J. L.; Rego-Machado, C. M.; Rodrigues, C. S.; Ueno, B.; de Morais, I. J.; Inoue-Nagata, A. K.
10.1101/2024.05.17.594728 — plant biology — Posted on 2024-05-20
1764 Cardioprotection by Poloxamer 188 is Mediated through Increased Endothelial Nitric Oxide Production
Chen, G.; Douglas, H. F.; Li, Z.; Cleveland, W. J.; Balzer, C.; Yannopolous, D.; Chen, I. Y.-L.; Obal, D.; Riess, M. L.
10.1101/2024.05.18.593838 — pharmacology and toxicology — Posted on 2024-05-20
1765 Growth generates a hyperdisordered pattern of chromatophores on squid skin
Ross, R. J. H.; Masucci, G. D.; Lin, C. Y.; Iglesias, T. L.; Reiter, S.; Pigolotti, S.
10.1101/2024.05.20.593453 — biophysics — Posted on 2024-05-20
1769 Small but mitey: long-read assembly of a streamlined mite genome from contaminated host plant sequencing data
Chen, S. H.; Jones, A.; Lu-Irving, P.; Yap, J.-Y. S.; van der Merwe, M.; Bragg, J. G.; Edwards, R. J.
10.1101/2024.05.17.594625 — genomics — Posted on 2024-05-20
1770 Improved cohesin HiChIP protocol and bioinformatic analysis for robust detection of chromatin loops and stripes
Jodkowska, K.; Parteka-Tojek, Z.; Agarwal, A.; Denkiewicz, M.; Korsak, S.; Chilinski, M.; Banecki, K.; Plewczynski, D.
10.1101/2024.05.16.594268 — genomics — Posted on 2024-05-20
1771 Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies
Wang, S.; Ojewunmi, O.; Kamiza, A.; Ramsay, M.; Morris, A.; Chikowore, T.; Fatumo, S.; Asimit, J. L.
10.1101/2024.05.17.594687 — genetics — Posted on 2024-05-20
1772 The nitrogen-fixing fern Azolla has a complex microbiome characterized by multiple modes of transmission
Song, M. J.; Li, F.-W.; Freund, F.; Tribble, C. M.; Toffelmier, E.; Miller, C.; Shaffer, H. B.; Rothfels, C.
10.1101/2024.05.20.592813 — ecology — Posted on 2024-05-20
1773 Millennial-scale societal shifts drive the widespread loss of a marine ecosystem
Lau, S. C. Y.; Thomas, M.; Williams, J. M.; Thurstan, R. H.; Hancock, B.; Russell, B. D.
10.1101/2024.05.19.594609 — ecology — Posted on 2024-05-20
1776 Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction
Ramasamy, P. K.; Matos, J. O.; Black, B. Y.; Ellenburg, W. H.; Chen, J.; Patterson, M.; Gehtman, J. A.; Theobald, D.; Krauss, I. J.; Oprian, D. D.
10.1101/2024.05.04.592530 — biochemistry — Posted on 2024-05-20
1781 Pan-cancer Analysis of Homologous Recombination Deficiency in Cell Lines
Dodson, A. E.; Shenker, S.; Sullivan, P.; Middleton, C.; McGuire, M.; Chipumuro, E.; Mishina, Y.; Tobin, E.; Cadzow, L.; Wylie, A. A.; Sangurdekar, D.
10.1101/2024.05.16.594524 — cancer biology — Posted on 2024-05-20
1783 A punctuated burst of massive genomic rearrangements by chromosome shattering and the origin of non-marine annelids
Vargas-Chavez, C.; Benitez-Alvarez, L.; Martinez-Redondo, G. I.; Alvarez-Gonzalez, L.; Salces-Ortiz, J.; Eleftheriadi, K.; Escudero, N.; Guiglielmoni, N.; Flot, J.-F.; Novo, M.; Ruiz-Herrera, A.; McLysaght, A.; Fernandez, R.
10.1101/2024.05.16.594344 — evolutionary biology — Posted on 2024-05-20
1784 A novel expression domain of extradenticle underlies the evolutionary developmental origin of the chelicerate patella
Klementz, B. C.; Brenneis, G.; Hinne, I. A.; Laumer, E. M.; Neu, S. M.; Hareid, G. M.; Gainett, G.; Setton, E. V.; Simian, C.; Vrech, D. E.; Joyce, I.; Barnett, A. A.; Patel, N. H.; Harvey, M. S.; Peretti, A. V.; Gulia-Nuss, M.; Sharma, P. P.
10.1101/2024.05.16.594547 — evolutionary biology — Posted on 2024-05-20
1786 Mechanical loading potentiates the bone response of anabolic osteoporosis treatments through mechanoregulation at the tissue level
Schulte, F. A.; Griesbach, J. K.; Weigt, C.; von Salis-Soglio, M.; Lambers, F. M.; Marques, F. C.; Kneissel, M.; Richards, P. J.; Kuhn, G. A.; Mueller, R.
10.1101/2024.05.16.594551 — bioengineering — Posted on 2024-05-20
1787 Optimal CXCR5 Expression during Tfh Maturation Involves the Bhlhe40-Pou2af1 Axis
Zhu, X.; Chen, X.; Cao, Y.; Liu, C.; Hu, G.; Ganesan, S.; Veres, T. Z.; Fang, D.; Liu, S.; Chung, H.; Germain, R. N.; Schwartzberg, P. L.; Zhao, K.; Zhu, J.
10.1101/2024.05.16.594397 — immunology — Posted on 2024-05-20
1789 Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
Algranati, D.; Oren, R.; Dassa, B.; Fellus-Alyagor, L.; Plotnikov, A.; Barr, H.; Harmelin, A.; London, N.; Ron, G.; Furth, N.; Shema, E.
10.1101/2024.02.05.578974 — cancer biology — Posted on 2024-05-20
1792 Taxonomy of human social perception
Santavirta, S.; Malen, T.; Erdemli, A.; Nummenmaa, L.
10.1101/2023.09.28.559888 — neuroscience — Posted on 2024-05-20
1794 Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development
Yue, T.; Guo, Y.; Qi, X.; Zheng, W.; Zhang, H.; Wang, B.; Zhou, B.; Zeng, X.; NA, O.; He, Y.; Su, B.
10.1101/2023.05.24.542081 — evolutionary biology — Posted on 2024-05-20
1796 Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer
Abdel Hadi, N.; Reyes-Castellanos, G.; Gicquel, T.; Gallardo-Arriaga, S.; Boet, E.; Sarry, J.-E.; Masoud, R.; IOVANNA, J. L.; Carrier, A.
10.1101/2022.12.28.522091 — cancer biology — Posted on 2024-05-20
1801 The wake- and sleep-modulating neurons of the lateral hypothalamic area demonstrate a differential pattern of degeneration in Alzheimers disease
Satpati, A.; Pereira, F. L.; Soloviev, A. V.; Mladinov, M.; Larsen, E.; Hua, S. L.; Tu, C.-L.; Leite, R. E. P.; Suemoto, C. K.; Rodriguez, R. D.; Paes, V. R.; Walsh, C.; Spina, S.; Seeley, W. W.; Pasqualucci, C. A.; Filho, W. J.; Chang, W.; Neylan, T. C.; Grinberg, L. T.
10.1101/2024.03.06.583765 — neuroscience — Posted on 2024-05-20
1803 Clade-defining mutations in human H1N1 hemagglutinin protein from 2021-2023 have opposing effects on in vitro fitness and antigenic drift
Swanson, N. J.; Girish, J.; Yunker, M.; Liu, H.; Norton, J.; Han, C.; Mostafa, H.; Fenstermacher, K.; Rothman, R. E.; Pekosz, A.
10.1101/2024.05.18.594815 — microbiology — Posted on 2024-05-19
1805 Inferring Bacterial Interspecific Interactions from Microcolony Growth Expansion
Miguel Trabajo, T.; Guex, I.; Dubey, M.; Sarton-Loheac, E.; Todorov, H.; Richard, X.; Mazza, C.; van der Meer, J. R.
10.1101/2024.05.19.594856 — microbiology — Posted on 2024-05-19
1809 The Mechanism underlying B cell Developmental Dysfunction in Kawasaki Disease Based on Single-cell Transcriptomic Sequencing
Lin, Q.; Wang, Z.; Ding, G.; Li, G.; Chen, L.; Qiu, Q.; Song, S.; Liu, W.; Jiang, X.; Shen, L.; Xiao, T.; Xie, L.
10.1101/2023.02.21.529340 — immunology — Posted on 2024-05-19
1810 Endogenous bystander killing mechanisms enhance the activity of novel FAP-CAR-T cells against glioblastoma
Yu, W.; Truong, N. T.; Polara, R.; Gargett, T.; Tea, M. N.; Pitson, S. M.; Ebert, L. M.; Brown, M. P.
10.1101/2023.02.21.529331 — immunology — Posted on 2024-05-19
1812 A neural geometry theory comprehensively explains apparently conflicting models of visual perceptual learning
Cheng, Y.-A.; Sanayei, M.; Chen, X.; Jia, K.; Li, S.; Fang, F.; Watanabe, T.; Thiele, A.; Zhang, R.-Y.
10.1101/2023.11.13.566963 — neuroscience — Posted on 2024-05-19
1813 A feedback-driven IoT microfluidic, electrophysiology, and imaging platform for brain organoid studies
Voitiuk, K.; Seiler, S. T.; Pessoa de Melo, M.; Geng, J.; Hernandez, S.; Schweiger, H. E.; Sevetson, J. L.; Parks, D. F.; Robbins, A.; Torres-Montoya, S.; Ehrlich, D.; Elliott, M. A. T.; Sharf, T.; Haussler, D.; Mostajo-Radji, M. A.; Salama, S. R.; Teodorescu, M.
10.1101/2024.03.15.585237 — neuroscience — Posted on 2024-05-19
1814 The exchange dynamics of biomolecular condensates
Zhang, Y.; Pyo, A. G. T.; Kliegman, R.; Jiang, Y.; Brangwynne, C. P.; Stone, H. A.; Wingreen, N. S.
10.1101/2022.03.16.484641 — biophysics — Posted on 2024-05-19
1816 All-in-one AAV-delivered epigenome-editing platform: proof-of-concept and therapeutic implications for neurodegenerative disorders
Kantor, B.; Odonovan, B.; Rittiner, J.; Hodgson, D.; Lindner, N.; Guerrero, S.; Dong, W.; Zhang, A.; Chiba-Falek, O.
10.1101/2023.04.14.536951 — bioengineering — Posted on 2024-05-19
1817 A multi-year longitudinal harmonization of quality controls in mass spectrometry proteomics core facilities
Chiva, C.; Olivella, R.; Staes, A.; Maia, T. M.; Panse, C.; Stejskal, K.; Douche, T.; Lombard, B.; Schuhmann, A.; Loew, D.; Mechtler, K.; Matondo, M.; Rettel, M.; Helm, D.; Impens, F.; Devos, S.; Shevchenko, A.; Nanni, P.; Sabido, E.
10.1101/2024.05.19.594517 — biochemistry — Posted on 2024-05-19
1818 Structural and Dynamical Analyses of Apo and Cap-binding eIF4E: An in silico Study
Hasegawa, K.; Burzachiello, J.; Connolly, L.; Kementzidis, G.; Niu, Z.; Papadopoulos, E.; Aktas, B. H.; Deng, Y.
10.1101/2024.05.18.594816 — biochemistry — Posted on 2024-05-19
1821 Strategies for effectively modelling promoter-driven gene expression using transfer learning
Reddy, A. J.; Herschl, M. H.; Geng, X.; Kolli, S.; Lu, A. X.; Kumar, A.; Hsu, P. D.; Levine, S.; Ioannidis, N. M.
10.1101/2023.02.24.529941 — genomics — Posted on 2024-05-19
1822 Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster
Mahmoudzadeh, N. H.; Heidarian, Y.; Tourigny, J. P.; Fitt, A. J.; Beebe, K.; Li, H.; Luhur, A.; Buddika, K.; Mungcal, L.; Kundu, A.; Policastro, R. A.; Brinkley, G. J.; Zentner, G. E.; Nemkov, T.; Pepin, R.; Chawla, G.; Sudarshan, S.; Rodan, A.; D'Alessandro, A.; Tennessen, J. M.
10.1101/2024.05.18.594772 — genetics — Posted on 2024-05-19
1823 Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progression
Sharifi, O.; Haghani, V.; Neier, K.; Fraga, K.; Korf, I.; Hakam, S. M.; Quon, G.; Johansen, N.; Yasui, D.; LaSalle, J. M.
10.1101/2024.05.16.594595 — genetics — Posted on 2024-05-19
1824 Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A
Jain, S.; Trinidad, M.; Nguyen, T. B.; Jones, K.; Diaz Neto, S.; Ge, F.; Glagovsky, A.; Jones, C.; Moran, G.; Wang, B.; Rahimi, K.; Zeynep Calici, S.; Cedillo, L. R.; Berardelli, S.; Ozden, B.; Chen, K.; Katsonis, P.; Williams, A.; Lichtarge, O.; Rana, S.; Pradhan, S.; Srinivasan, R.; Sajeed, R.; Joshi, D.; Faraggi, E.; Jernigan, R.; Kloczkowski, A.; Xu, J.; Song, Z.; Ozkan, S.; Padilla, N.; de la Cruz, X.; Acuna-Hidalgo, R.; Grafmuller, A.; Jimenez Barron, L. T.; Manfredi, M.; Savojardo, C.; Babbi, G.; Martelli, P. L.; Casadio, R.; Sun, Y.; Zhu, S.; Shen, Y.; Pucci, F.; Rooman, M.; Cia, G.; R
10.1101/2024.05.16.594558 — genetics — Posted on 2024-05-19
1825 fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans
Tuckowski, A. M.; Beydoun, S.; Kitto, E. S.; Bhat, A.; Howington, M. B.; Sridhar, A.; Bhandari, M.; Chambers, K.; Leiser, S. F.
10.1101/2024.05.17.594584 — genetics — Posted on 2024-05-19
1826 The landscape of gene loss and missense variation across the mammalian tree informs on gene essentiality
Liao, C.; Ye, R.; Ivankovic, F.; Fu, J.; Walters, R. K.; Lowther, C.; Valkanas, E.; Churchhouse, C.; Samocha, K. E.; Lindblad-Toh, K.; Karlsson, E.; Hiller, M.; Talkowski, M. E.; Neale, B.
10.1101/2024.05.16.594531 — genetics — Posted on 2024-05-19
1831 Recruitment of CTCF to the SIRT1 promoter after Oxidative Stress mediates Cardioprotective Transcription
Wagner, T.; Priyanka, P.; Micheletti, R.; Friedman, M. J.; Nair, S. J.; Gamliel, A.; Taylor, H.; Song, X.; Cho, M.; Oh, S.; Li, W.; Han, J.; Ohgi, K. A.; Abrass, M.; D'Antonio-Chronowska, A.; D'Antonio, M.; Hazuda, H.; Duggirala, R.; Blangero, J.; Ding, S.; Guzmann, C.; Frazer, K.; Aggarwal, A. K.; Zemljic-Harpf, A. E.; Rosenfeld, M. G.; Suh, Y.
10.1101/2024.05.17.594600 — cell biology — Posted on 2024-05-19
1832 Harnessing homeostatically active RhoC at cell junctions preserves human endothelial barrier function during inflammation
Colas-Algora, N.; Munoz-Pinillos, P.; Barroso, S.; Cacho-Navas, C.; Caballero, A.; Cerro-Tello, G.; de Rivas, G.; Gonzalez-Fernandez, M.; Jimenez-Alfaro, I.; Fresno, M.; Ribas, C.; Paradela, A.; Lopez-Collazo, E.; Fernandez, J.-J.; Millan, J.
10.1101/2024.05.17.594667 — cell biology — Posted on 2024-05-19
1833 Circadian Coupling Orchestrates Cell Growth
Gutu, N. N.; Nordentoft, M.; Kuhn, M.; Ector, C.; Finger, A. M.; Heltberg, M. S.; Jensen, M. H.; Keilholz, U.; Kramer, A.; Herzel, H.; Granada, A. E.
10.1101/2024.05.18.594797 — cell biology — Posted on 2024-05-19
1834 Morphological single-cell analysis of peripheral blood mononuclear cells from 390 healthy blood donors with Blood Cell Painting
Hogel-Starck, C.; Timonen, V. A.; Atarsaikhan, G.; Mogollon, I.; Polso, M.; Hassinen, A.; Honkanen, J.; Soini, J.; Ruokoranta, T.; Ahlnas, T.; Juvila, J.; Miettinen, J. J.; Rodosthenous, R.; Arvas, M.; FinnGen, ; Heckman, C. A.; Partanen, J.; Daly, M.; Palotie, A.; Paavolainen, L.; Pietiainen, V.; Pitkanen, E.
10.1101/2024.05.17.594648 — cell biology — Posted on 2024-05-19
1835 Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization
Yang, M.; Adegbite, O.; Chang, P.; Zhu, X.; Li, Y.; Dykes, G.; Chen, Y.; Savage, N.; Hinton, J. C. D.; Lian, L.-Y.; Liu, L.-N.
10.1101/2024.05.17.594633 — cell biology — Posted on 2024-05-19
1837 Microglial depletion decreases Müller cell maturation and inner retinal vascular density
Rowthorn-Apel, N.; Vridhachalam, N.; Connor, K. M.; Bonilla, G. M.; Sadreyev, R.; Singh, C.; Gnanaguru, G.
10.1101/2024.05.16.594541 — cell biology — Posted on 2024-05-19
1838 Extracellular Matrix-Induced Genes May Reduce Response to Rapamycin in LAM
Clements, D.; Babaei-Jadidi, R.; Miller, S.; Shah, N.; Sand, J. M. B.; Leeming, D. J.; Borthwick, L. A.; Fisher, A. J.; Dufour, A.; Johnson, S. R.
10.1101/2024.05.16.594484 — cell biology — Posted on 2024-05-19
1839 Ubiquitin-driven protein condensation initiates clathrin-mediated endocytosis
Yuan, F.; Gollapudi, S.; Day, K.; Ashby, G.; Sangani, A.; Malady, B.; Wang, L.; Lafer, E. M.; Huibregtse, J.; Stachowiak, J.
10.1101/2023.08.21.554139 — cell biology — Posted on 2024-05-19
1840 TMEM165 replenishes lysosomal calcium stores, protects cells against calcium overload, and mediates calcium-induced lysosomal H+ leakage
Chan, R.; Liu, B.; Jaslan, D.; Kujec, L.; Kurdina, V.; Warnke, B.; Klingl, Y.; Petrauskas, A.; Maeda, K.; Grimm, P. D. D. C. M.; Jaattela, M.
10.1101/2024.05.09.593345 — cell biology — Posted on 2024-05-19
1841 Cryo-EM structure of the bicarbonate receptor GPR30
Kaneda, S.; Jo-Watanabe, A.; Akasaka, H.; Oshima, H. S.; Yokomizo, T.; Shihoya, W.; Nureki, O.
10.1101/2024.05.19.594840 — biochemistry — Posted on 2024-05-19
1842 Spatial dynamics of peripheral and central nervous system infection by an interferon-inducing neuroinvasive virus
Laghi, V.; Boucontet, L.; Wiggett, H.; Banerjee, P.; Simion, M.; Maggi, L.; Ciura, S.; Guedj, J.; Colucci-Guyon, E.; Levraud, J.-P.
10.1101/2024.05.19.594871 — microbiology — Posted on 2024-05-19
1843 Genomic Signatures of Microgeographic Adaptation in Anopheles coluzzii Along an Anthropogenic Gradient in Gabon
Daron, J.; Bouafou, L.; Tennessen, J.; Rahola, N.; Makanga, B.; Akone-Ella, O.; Ngangue, M.; Longo Pendy, N.; Paupy, C.; Neafsey, D. E.; Fontaine, M. C.; Ayala, D.
10.1101/2024.05.16.594472 — evolutionary biology — Posted on 2024-05-19
1845 Intra-amygdala circuits of sleep disruption-induced anxiety in female mice
Peng, B.; Foilb, A. R.; Manasian, Y.; Li, Y.; Deng, X.; Meloni, E. G.; Ressler, K. J.; Carlezon, W. A.; Bolshakov, V. Y.
10.1101/2024.05.19.594863 — neuroscience — Posted on 2024-05-19
1849 Dynamic changes in mitochondria support phenotypic flexibility of microglia
Espinoza, K.; Schaler, A. W.; Gray, D. T.; Sass, A.; Moore, K.; Yu, M.; Chamorro, C.; De Biase, L. M.
10.1101/2024.05.18.594002 — neuroscience — Posted on 2024-05-19
1852 Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain
Herwerth, M.; Wyss, M. T.; Schmid, N. B.; Condrau, J.; Ravotto, L.; Mateos Melero, J. M.; Kaech, A.; Bredell, G.; Thomas, C.; Stadelmann, C.; Misgeld, T.; Bennett, J. L.; Saab, A. S.; Jessberger, S.; Weber, B.
10.1101/2024.05.18.594292 — neuroscience — Posted on 2024-05-19
1853 Hidden state inference requires abstract contextual representations in ventral hippocampus
Mishchanchuk, K.; Gregoriou, G.; Qu, A. J.; Kastler, A.; Huys, Q.; Wilbrecht, L.; MacAskill, A. F.
10.1101/2024.05.17.594673 — neuroscience — Posted on 2024-05-19
1856 Transcriptional Regulators with Broad Expression in the Zebrafish Spinal Cord
England, S. J.; Campbell, P.; Banerjee, S.; Bates, R.; Grieb, G.; Fancher, W.; Lewis, K.
10.1101/2024.02.14.580357 — developmental biology — Posted on 2024-05-19
1857 KAT3 mutations impair neural crest migration through EMT regulators snai1b and snai2 in Rubinstein Taybi Syndrome
Verma, S.; Dalabehera, S.; Gowda, S.; Chandrasekaran, K.; Singh, D.; Prasher, B.; Bapat, S.; Ramalingam, S.; Sachidanandan, C.
10.1101/2024.05.19.593474 — developmental biology — Posted on 2024-05-19
1867 Perceptual learning improves discrimination while distorting appearance
Szpiro, S. F. A.; Burlingham, C. S.; Simoncelli, E. P.; Carrasco, M.
10.1101/2022.09.08.507104 — neuroscience — Posted on 2024-05-19
1868 Identification of Fibrinogen as a Plasma Protein Binding Partner for Lecanemab Biosimilar IgG: Implications for Alzheimer's Disease Therapy
Bellier, J.-P.; Roman, A.; Christiano, C.; Anzai, J. A.; Moreno, S.; Campbell, E. C.; Godwin, L.; Li, A.; Chen, A.; Alan, S. M.; Saba, A.; Yoo, H. b.; Yang, H.-S.; Chhatwal, J. P.; Selkoe, D. J.; Liu, L.
10.1101/2024.05.01.591892 — neuroscience — Posted on 2024-05-19
1869 Calcium-independent lipid release from astrocytes modulates neuronal excitability
Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.
10.1101/2020.01.12.903393 — neuroscience — Posted on 2024-05-19
1870 Spatially conserved pathoprotein profiling in the human suprachiasmatic nucleus in progressive Alzheimer disease stages
Son, G.; Mladinov, M.; Pereira, F.; Li, S. H.; Tu, C.-L.; Judge, G.; Yang, Y.; Suemoto, C.; Leite, R.; Paes, V.; Pasqualucci, C.; Jacob-Filho, W.; Spina, S.; Seeley, W.; Chang, W.; Neylan, T.; Grinberg, L. T.
10.1101/2024.03.07.584000 — neuroscience — Posted on 2024-05-19
1872 Specification of human regional brain lineages using orthogonal gradients of WNT and SHH in organoids
Scuderi, S.; Kang, T.-Y.; Jourdon, A.; Yang, L.; Wu, F.; Nelson, A.; Anderson, G. M.; Mariani, J.; SARANGI, V.; Abyzov, A.; Levchenko, A.; Vaccarino, F. M.
10.1101/2024.05.18.594828 — neuroscience — Posted on 2024-05-19
1875 Tagless LysoIP method for molecular profiling of lysosomal content in clinical samples
Saarela, D.; Lis, P.; Gomes, S.; Nirujogi, R. S.; Dong, W.; Rawat, E.; Glendinning, S.; Zeneviciute, K.; Bagnoli, E.; Fasimoye, R.; Lin, C.; Nyame, K.; Boros, F. A.; Zunke, F.; Lamoliatte, F.; Elshani, S.; Jaconnelli, M.; Jans, J. J. M.; Huisman, M. A.; Posern, C.; Westermann, L. M.; Schulz, A.; van Hasselt, P. M.; Alessi, D. R.; Abu-Remaileh, M.; Sammler, E.
10.1101/2024.05.17.594681 — cell biology — Posted on 2024-05-19
1876 An adaptable plasmid scaffold for CRISPR-based endogenous tagging
Philip, R.; Sharma, A.; Matellan, L.; Erpf, A. C.; Hsu, W.-H.; Tkach, J. M.; Wyatt, H. D. M.; Pelletier, L.
10.1101/2023.11.01.565029 — molecular biology — Posted on 2024-05-19
1877 Dietary protein source strongly alters gut microbiota composition and function
Blakeley-Ruiz, J. A.; Bartlett, A.; McMillan, A. S.; Awan, A.; Vanhoy Walsh, M.; Meyerhoffer, A. K.; Vintila, S.; Maier, J. L.; Richie, T.; Theriot, C. M.; Kleiner, M.
10.1101/2024.04.04.588169 — microbiology — Posted on 2024-05-19
1878 Inhibitory control of gait initiation in humans: an electroencephalography study
Ziri, D.; Hugueville, L.; Olivier, C.; Boulinguez, P.; Gunasekaran, H.; Lau, B.; Welter, M.-L.; GEORGE, N.
10.1101/2024.01.25.577273 — neuroscience — Posted on 2024-05-19
1884 Physiological role and mechanisms of action for a long noncoding haplotype region
Xue, H.; Mishra, M. K.; Liu, Y.; Liu, P.; Grzybowski, M.; Pandey, R.; Usa, K.; Vanden Avond, M.; Bala, N.; Alli, A. A.; Cowley, A. W.; Qiu, Q.; Greene, A. S.; Rao, S.; O'Meara, C. C.; Geurts, A.; Liang, M.
10.1101/2024.05.15.594413 — genetics — Posted on 2024-05-18
1885 Exploring the dynamic ticks-camel-pathogens interaction
Makwatta, J. O.; Ndegwa, P. N.; Oyieke, F. A.; Ahuya, P.; Masiga, D.; Getahun, M. N.
10.1101/2024.05.15.594365 — ecology — Posted on 2024-05-18
1887 Autofluorescence lifetime flow cytometry with time-correlated single photon counting
Samimi, K.; Pasachhe, O.; Guzman, E. C.; Riendeau, J.; Gillette, A. A.; Pham, D. L.; Wiech, K. J.; Moore, D. L.; Skala, M. C.
10.1101/2024.05.15.594394 — cell biology — Posted on 2024-05-18
1891 Unraveling the impact of host genetics and factors on the urinary microbiome in a young population
Zou, L.; Zhang, Z.; Guo, R.; Tong, X.; Chen, J.; Ju, Y.; Lu, H.; Yang, H.; Wang, J.; Zong, Y.; Xu, X.; Jin, X.; Xiao, L.; Zhang, T.; Liu, X.
10.1101/2024.05.17.594782 — microbiology — Posted on 2024-05-18
1892 Antigen-driven expansion of public clonal T cell populations in inflammatory bowel diseases
Pesesky, M. W.; Bharanikumar, R.; Le Bourhis, L. W.; ElAbd, H.; Carty, C.; Singh, N.; Bokemeyer, B.; Schreiber, S.; Goerg, S.; Noceda, M. G.; Gittelman, R. M.; May, D. H.; Dines, J. N.; Zhou, W.; Kaplan, I. M.; Snyder, T. M.; Zahid, H. J.; Chen-Harris, H.; Howie, B.; Franke, A.; Robins, H.; Allez, M.
10.1101/2024.05.15.594220 — immunology — Posted on 2024-05-18
1894 Xist Deletion in B Cells Results in Systemic Lupus Erythematosus Phenotypes
Lovell, C. D.; Jiwrajka, N.; Amerman, H. K.; Cancro, M. P.; Anguera, M.
10.1101/2024.05.15.594175 — immunology — Posted on 2024-05-18
1895 A plant-specific clade of serine/arginine-rich proteins regulates RNA splicing homeostasis and thermotolerance in tomato
Rosenkranz, R. R.; Vraggalas, S.; Keller, M.; Sankaranarayanan, S.; McNicoll, F.; Loechli, K.; Bublak, D.; Benhamed, M.; Crespi, M.; Berberich, T.; Bazakos, C.; Feldbruegge, M.; Schleiff, E.; Mueller-McNicoll, M.; Zarnack, K.; Fragkostefanakis, S.
10.1101/2024.05.15.594399 — plant biology — Posted on 2024-05-18
1896 Expanding the Triangle of U: The genome assembly of Hirschfeldia incana provides insights into chromosomal evolution, phylogenomics and high photosynthesis-related traits
Hoang, N. V.; Walden, N.; Caracciolo, L.; Luoni, S. B.; Retta, M.; Li, R.; Wolters, F. C.; Woldu, T.; Becker, F. F. M.; Verbaarschot, P.; Harbinson, J.; Driever, S. M.; Struik, P. C.; Amerongen, H. v.; de Ridder, D.; Aarts, M. G. M.; Schranz, M. E.
10.1101/2024.05.16.593662 — plant biology — Posted on 2024-05-18
1898 Reduced beta-hydroxybutyrate disposal after ketogenic diet feeding in mice
Cousineau, C. M.; Snyder, D.; Redd, J. R.; Turner, S.; Carr, T.; Bridges, D.
10.1101/2024.05.16.594369 — physiology — Posted on 2024-05-18
1903 IB-DNQ and Rucaparib dual treatment alters cell cycle regulation and DNA repair in triple negative breast cancer cells
Runnebohm, A. M.; Wijeratne, H. S.; Peck Justice, S. A.; Wijeratne, A. B.; Roy, G.; Singh, N.; Hergenrother, P.; Boothman, D. A.; Motea, E. A.; Mosley, A. L.
10.1101/2024.05.15.594427 — cancer biology — Posted on 2024-05-18
1911 Kinetic properties of optogenetic DNA editing by LiCre-loxP
Dufour, A.; Duplus-Bottin, H.; Boukeke-Lesplulier, T.; Casassa, E.; Triqueneaux, G.; Darthenay-Kiennemann, C.; Dumont, A.; Moali, C.; Vittoz, F.; Jost, D.; Yvert, G.
10.1101/2024.05.17.594525 — bioengineering — Posted on 2024-05-18
1913 State diagrams of type I collagen for the rational design of biomimetic materials
Martinier, I.; Deville, S.; Mosser, G.; Trichet, L.; Davidson, P.; Fernandes, F. M.
10.1101/2024.05.17.594626 — bioengineering — Posted on 2024-05-18
1915 Endemic demographics of the Jomon people estimated based on complete mitogenomes reveal their regional diversity
Yoshida, K.; Wakiyama, Y.; Valverde, G.; Tanino, A.; Waku, D.; Katsumura, T.; Ogawa, M.; Nagaoka, T.; Hirata, K.; Koganebuchi, K.; Watanabe, Y.; Ohashi, J.; Yoneda, M.; Takahashi, R.; Oota, H.
10.1101/2024.05.16.594064 — genomics — Posted on 2024-05-18
1917 Frequencies of house fly proto-Y chromosomes across populations are predicted by temperature heterogeneity within populations
Foy, P. D.; Loetzerich, S. R.; Boxler, D.; Burgess, E. R.; Trout Fryxell, R. T.; Gerry, A. C.; Hinkle, N. C.; Machtinger, E. T.; Olds, C.; Tarone, A. M.; Watson, W.; Scott, J. G.; Meisel, R. P.
10.1101/2024.05.15.594357 — evolutionary biology — Posted on 2024-05-18
1922 Protein CoAlation on TXNRD2 regulates mitochondrial thioredoxin system to protect against ferroptosis
Lin, C.-C.; Lin, Y.-T.; Chen, S.-Y.; Setayeshpour, Y.; Chen, Y.; Dunn, D. E.; Soderblom, E. J.; Zhang, G.; Filonenko, V.; Jeong, S. Y.; Floyd, S. R.; Hayflick, S.; Gout, I.; Chi, J.-T. A.
10.1101/2024.05.16.594391 — cell biology — Posted on 2024-05-18
1923 Deep mutational scanning of influenza A virus NEP reveals pleiotropic mutations in its N-terminal domain
Teo, Q. W.; Wang, Y.; Lv, H.; Mao, K. J.; Tan, T. J. C.; Huan, Y. W.; Rivera-Cardona, J.; Shao, E. K.; Choi, D.; Dargani, Z. T.; Brooke, C. B.; Wu, N. C.
10.1101/2024.05.16.594574 — cell biology — Posted on 2024-05-18
1924 Frequent and asymmetric cell division in endosymbiotic bacteria of cockroaches
Noda, T.; Mizutani, M.; Harumoto, T.; Katsuno, T.; Koga, R.; Fukatsu, T.
10.1101/2024.05.17.594780 — microbiology — Posted on 2024-05-18
1925 CPT2 mediated fatty acid oxidation is dispensable for humoral immunity
Zeng, H.; Li, M.; Zhou, X.; Zhu, X.; Li, Y.; Hitosugi, T.; Li, Y.
10.1101/2024.05.15.594133 — immunology — Posted on 2024-05-18
1926 mosGraphGen: a novel tool to generate multi-omic signaling graphs to facilitate integrative and interpretable graph AI model development
Zhang, H.; Cao, D.; Chen, Z.; Zhang, Z.; Chen, Y.; Sessions, C.; Cruchaga, C.; Payne, P. R.; Li, G.; Province, M.; Li, F.
10.1101/2024.05.15.594360 — systems biology — Posted on 2024-05-18
1927 Building Brains for Robots: A Hands-On Approach to Learning Neuroscience in the Classroom
Kannan, R.; Gendreau, M.; Hatch, A.; Free, S. K.; Muriungi, K.; Garje, Y. A.; DeBoer, J.; Gage, G. J.; Harris, C. A.
10.1101/2024.05.15.594177 — scientific communication and education — Posted on 2024-05-18
1933 Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stress
Chen, B.; Prabhu, A.; Li, G.; Kaltenbach, A.; Wang, Y.; Shakir, G.; Natarelli, L.; Megens, R.; Jansen, Y.; Ramanathan, S.; Geiger, M.; Faussner, A.; Hristov, M.; Richter, D.; Di, X.; van der Stelt, M.; Li, Z.; Sachs, N.; Paloschi, V.; Maegdefessel, L.; Hofmann, S. M.; Weber, C.; Herzig, S.; Prats, R. G.; Steffens, S.
10.1101/2024.05.15.594375 — immunology — Posted on 2024-05-18
1936 The ancient evolution of far-red light photoacclimation in cyanobacteria
Antonaru, L. A.; Rad-Menendez, C.; Mbedi, S.; Sparmann, S.; Pope, M.; Oliver, T.; Wu, S.; Green, D.; Gugger, M.; Nürnberg, D. J.
10.1101/2024.05.15.594131 — evolutionary biology — Posted on 2024-05-18
1938 Comparative transcriptomics reveal a highly polymorphic Xanthomonas HrpG virulence regulon
Quiroz Monnens, T.; Roux, B.; Cunnac, S.; Charbit, E.; Carrere, S.; Lauber, E.; Jardinaud, M.-F.; Darrasse, A.; Arlat, M.; Szurek, B.; Pruvost, O.; Jacques, M.-A.; Gagnevin, L.; Koebnik, R.; Noël, L. D.; Boulanger, A.
10.1101/2024.05.17.594730 — microbiology — Posted on 2024-05-18
1940 Neuronal migration depends on blood flow in the adult brain
Ogino, T.; Saito, A.; Sawada, M.; Takemura, S.; Nagase, J.; Kawase, H.; Inada, H.; Herranz-Perez, V.; Mukouyama, Y.-S.; Ema, M.; Garcia-Verdugo, J. M.; Nabekura, J.; Sawamoto, K.
10.1101/2024.05.16.594485 — neuroscience — Posted on 2024-05-18
1942 Adipose microenvironment promotes hypersialylation of ovarian cancer cells
Fox, A.; Leonard, G. D.; Adzibolosu, N.; Wong, T.; Tejda, R.; Sharma, S.; Gogoi, R.; Morris, R.; Gil, M.; Fehl, C.; Alvero, A. B.
10.1101/2024.05.13.593990 — cancer biology — Posted on 2024-05-18
1944 Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
Bisaro, F.; Jackson-Litteken, C. D.; McGuffey, J. C.; Hooppaw, A. J.; Bodrog, S.; Jebeli, L.; Ortiz-Marquez, J. C.; van Opijnen, T.; Scott, N.; Di Venanzio, G.; Feldman, M.
10.1101/2024.05.17.594771 — microbiology — Posted on 2024-05-18
1945 Mass mortality associated with Carpione Rhabdovirus in golden pompano (Trachinotus ovatus) in China: First report
Sun, H.; Huang, J.; Wang, H.; Zhang, Y.; Fei, Q.; Zhou, J.; Yang, L.; Li, Y.; Cai, S.; Huang, Y.
10.1101/2024.05.14.594202 — microbiology — Posted on 2024-05-18
1946 Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases
Saposnik, L. M.; Coria, L. M.; Bruno, L.; Guaimas, F.; Pandolfi, J. B.; Pol, M.; Urga, M. E.; Sabbione, F.; McClelland, M.; Trevani, A.; Pasquevich, K. A.; Cassataro, J.
10.1101/2024.05.15.594389 — microbiology — Posted on 2024-05-18
1947 Cell-of-origin epigenome underlies SS18::SSX-mediated transformation
Hill, L. A.; Scott, R. W.; Martin, L. A.; Arostegui, M.; Davenport, G.; Vemon, M.; Hofvander, J.; Wang, X. Q.; Li, J.; Nielsen, T.; Jones, K. B.; Hirst, M.; Underhill, T. M.
10.1101/2024.05.15.594021 — cancer biology — Posted on 2024-05-18
1949 Netrin G1 Ligand is a new stromal immunomodulator that promotes pancreatic cancer
Barbosa Vendramini-Costa, D.; Francescone, R.; Franco-Barraza, J.; Luong, T.; Graves, M.; Musa de Aquino, A.; Steele, N. G.; Gardiner, J. C.; Alcantara dos Santos, S. A.; Ogier, C.; Malloy, E.; Borghaei, L.; Martinez, E.; Zhigarev, D. I.; Tan, Y.; Lee, H.; Zhou, Y.; Cai, K. Q.; Klein-Szanto, A. J.; Wang, H.; Andrake, M.; Dunbrack, R. L.; Campbell, K. S.; Cukierman, E.
10.1101/2024.05.15.594354 — cancer biology — Posted on 2024-05-18
1950 Actin cytoskeleton dynamics affect replication of Human Metapneumovirus
Rodriguez, P. E.; Gil, P. I.; Camara, J. A.; Camara, A.; Paglini, M. G.
10.1101/2022.09.30.510364 — microbiology — Posted on 2024-05-18
1951 Non-Hebbian plasticity transforms transient experiences into lasting memories
Faress, I.; Khalil, V.; Hou, W.-H.; Moreno, A.; Andersen, N.; Fonseca, R.; Piriz, J.; Capogna, M.; Nabavi, S.
10.1101/2023.04.06.535862 — neuroscience — Posted on 2024-05-18
1952 CoRAL accurately resolves extrachromosomal DNA genomestructures with long-read sequencing
Zhu, K.; Jones, M. G.; Luebeck, J.; Bu, X.; Yi, H.; Hung, K. L.; Wong, I. T.-L.; Zhang, S.; Mischel, P. S.; Chang, H. Y.; Bafna, V.
10.1101/2024.02.15.580594 — cancer biology — Posted on 2024-05-18
1953 A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation
Amico, T.; Dada, S.; Lazzari, A.; Brezinova, M.; Trovato, A.; Vendruscolo, M.; Fuxreiter, M.; Maritan, A.
10.1101/2023.04.11.536478 — biophysics — Posted on 2024-05-18
1956 The X-Linked Intellectual Disability gene, ZDHHC9, is important for oligodendrocyte subtype determination and myelination
Hollman, R. B.; Wild, A. R.; O'Leary, T. P.; Thompson, A. J.; Flibotte, S.; Poblete, T. O.; Peng, A.; Rogalski, J. C.; Gill, G.; Bamji, S. X.
10.1101/2023.08.08.552342 — neuroscience — Posted on 2024-05-18
1958 Cortical Dynamics during Contour Integration
He, D.; Yang, A.; Coates, D. R.; Ogmen, H.; Chung, S. T.
10.1101/2024.05.13.594033 — neuroscience — Posted on 2024-05-18
1962 Plasmacytoid dendritic cells mediate CpG-ODN induced increase in survival in a mouse model of lymphangioleiomyomatosis
Amosu, M.; Jankowski, A. M.; McCright, J. C.; Yang, B.; Fernandez, J. G. d. O.; Moore, K.; Gadde, H. S.; Kaluzienski, M.; Maisel, K.
10.1101/2023.02.06.527331 — immunology — Posted on 2024-05-18
1965 Dendritic excitations govern back-propagation via a spike-rate accelerometer
Park, P.; Wong-Campos, J. D.; Itkis, D.; Lee, B. H.; Qi, Y.; Davis, H. C.; Antin, B.; Pasarkar, A. P.; Grimm, J. B.; Plutkis, S. E.; Holland, K. L.; Paninski, L.; Lavis, L.; Cohen, A. E.
10.1101/2023.06.02.543490 — neuroscience — Posted on 2024-05-18
1967 Dimerization activates the Inversin complex in C. elegans
Beyrent, E.; Wei, D. T.; Beacham, G. M.; Park, S.; Zheng, J.; Paszek, M. J.; Hollopeter, G.
10.1101/2024.05.17.594761 — cell biology — Posted on 2024-05-18
1968 Controlling lipid droplet dynamics via tether condensates
Amari, C.; Simon, D.; Bellon, T.; Plamont, M.-A.; Thiam, A.-R.; Gueroui, Z.
10.1101/2024.05.15.594395 — cell biology — Posted on 2024-05-18
1970 Wings expansion in Drosophila melanogaster
Hadjaje, S.; Silva, I. A.; Dalbe, M.-J.; Clement, R.; Marthelot, J.
10.1101/2024.05.17.594352 — biophysics — Posted on 2024-05-18
1972 SNX10 regulates the clearance of mitochondrial proteins and mitochondrial bioenergetics
Trachsel-Moncho, L.; Mathai, B. J.; Veroni, C.; Lapao, A.; Singh, S.; Asp, N. T.; Schultz, S. W.; Pankiv, S.; Simonsen, A.
10.1101/2024.05.15.594320 — cell biology — Posted on 2024-05-18
1973 The phylogenetic position of the Yunxian cranium elucidates the origin of Dragon Man and the Denisovans
Feng, X.; Lu, D.; Gao, F.; Fang, Q.; Feng, Y.; Huang, X.; Tan, C.; Zhou, H.; Li, Q.; Zhang, C.; Stringer, C.; Ni, X.
10.1101/2024.05.16.594603 — evolutionary biology — Posted on 2024-05-17
1975 Machine Learning and Directed Evolution of Base Editing Enzymes
Perrotta, R. M.; Vinke, S.; Ferreira, R.; Moret, M.; Mahas, A.; Chiappino-Pepe, A.; Riedmayr, L. M.; Lehmann, L.; Mehra, A.-T.; Church, G.
10.1101/2024.05.17.594556 — synthetic biology — Posted on 2024-05-17
1978 CellSeg3D: self-supervised 3D cell segmentation for microscopy
Achard, C.; Kousi, T.; Frey, M.; Vidal, M.; Paychere, Y.; Hofmann, C.; Iqbal, A.; Hausmann, S. B.; Pages, S.; Mathis, M. W.
10.1101/2024.05.17.594691 — cell biology — Posted on 2024-05-17
1979 Distinct components of nucleoside-modified messenger RNA vaccines cooperate to instruct efficient germinal center responses
Bettini, E.; Chudnovskiy, A.; Protti, G.; Nakadakari-Higa, S.; Ceglia, S.; Castano, D.; Chiu, J.; Muramatsu, H.; Mdluli, T.; Abraham, E.; Lipinszki, Z.; Maillard, I.; Tam, Y.; Reboldi, A.; Pardi, N.; Spreafico, R.; Victora, G. D.; Locci, M.
10.1101/2024.05.17.594726 — immunology — Posted on 2024-05-17
1981 Melanoma antigens in pediatric medulloblastoma contribute to tumor heterogeneity and species-specificity of group 3 tumors
Collins, R. R. J.; Gee, R. R. F.; Sanchez, M. C. H.; Tozandehjani, S.; Bayat, T.; Breznik, B.; Lee, A. K.; Peters, S. T.; Connelly, J. P.; Pruett-Miller, S. M.; Roussel, M. F.; Rakheja, D.; Tillman, H. S.; Potts, P. R.; Fon Tacer, K.
10.1101/2024.05.14.594201 — cancer biology — Posted on 2024-05-17
1988 Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq
Morgan, I. L.; McKie, S. J.; Kim, R.; Seol, Y.; Xu, J.; Harami, G.; Maxwell, T.; Neuman, K.
10.1101/2024.05.17.594727 — biochemistry — Posted on 2024-05-17
1989 Structural insights into Pseudomonas aeruginosa lysine-specific uptake mechanism for extremely low pH regulation
Bicer, D.; Matsuoka, R.; Moumbock, A. F. A.; Sukumar, P.; Cheruvara, H.; Quigley, A.; Pardon, E.; Steyaert, J.; Henderson, P. J. F.; Caffrey, M.; Griese, J. J.; Nji, E.
10.1101/2024.05.17.594718 — biochemistry — Posted on 2024-05-17
1991 RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability
Provasek, V.; Bacolla, A.; Rangaswamy, S.; Mitra, J.; Kodavati, M.; Yusuf, I.; Malojirao, V.; Vasquez, V.; Britz, G. W.; Li, G.-M.; Xu, Z.; Mitra, S.; Garruto, R. M.; Tainer, J.; Hegde, M.
10.1101/2024.05.16.594552 — biochemistry — Posted on 2024-05-17
1992 Determination of permissive and restraining cancer-associated fibroblast (DeCAF) subtypes
Peng, X. L.; Kharitonova, E. V.; Xu, Y.; Kearney, J. F.; Luan, C.; Chan, P. S.; Hariharan, A.; McCabe, I. C.; Leary, J. R.; Morrison, A. B.; Trembath, H. E.; LaBella, M. E.; Herrera, S. G.; Cliff, A.; Kim, H. J.; Belt, B. A.; Panni, R. Z.; Linehan, D. C.; Damrauer, J. S.; Iuga, A. C.; Kim, W. Y.; Rashid, N. U.; Yeh, J. J.
10.1101/2024.05.14.594197 — genomics — Posted on 2024-05-17
1994 Recombinant inbred line panels inform the genetic architecture and interactions of adaptive traits in Drosophila melanogaster
Ribeiro, T. d. S.; Lollar, M. J.; Sprengelmeyer, Q. D.; Huang, Y.; Benson, D. M.; Orr, M. S.; Johnson, Z. C.; Corbett-Detig, R. B.; Pool, J. E.
10.1101/2024.05.14.594228 — evolutionary biology — Posted on 2024-05-17
1995 Spatiotemporal dynamic models of Amblyomma americanum questing activity in the Central Great Plains
Cobos, M. E.; Winters, T.; Martinez, I.; Yao, Y.; Xiao, X.; Ghosh, A.; Sundstrom, K.; Duncan, K.; Brennan, R. E.; Little, S. E.; Peterson, A. T.
10.1101/2024.05.14.594229 — ecology — Posted on 2024-05-17
1999 Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics
Xie, P.; Jiang, X.; He, J.; Pan, Q.; Yang, X.; Zheng, Y.; Fan, W.; Wu, C.; Zheng, W.; Fang, K.; Si, S.; Zhu, S.; Yang, Y.; Zhong, T. P.; Yang, Z.; Wei, K.; Xie, W.; Jing, N.; Luo, Z.; Lin, C.
10.1101/2024.05.17.594655 — molecular biology — Posted on 2024-05-17
2000 A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
Lukasiak, S.; Kalinka, A.; Gupta, N.; Papadopoulos, A.; Saeed, K.; McDermott, U.; Hannon, G. J.; Ross-Thriepland, D.; Walter, D.
10.1101/2024.05.17.594311 — molecular biology — Posted on 2024-05-17
2001 Stabilizing mammalian RNA thermometer confers neuroprotection in subarachnoid hemorrhage
Zhang, M.; Zhang, B.; Liu, C.; PreuBner, M.; Ayachit, M.; Li, W.; Huang, Y.; Liu, D.; He, Q.; Emmerichs, A.-K.; Meinke, S.; Chen, S.; Wang, L.; Zheng, L.; Li, Q.; Huang, Q.; Haltenhof, T.; Gao, R.; Qin, X.; Cheng, A.; Wei, T.; Yu, L.; Schubert, M.; Gao, X.; Li, M.; Heyd, F.
10.1101/2024.05.17.594628 — molecular biology — Posted on 2024-05-17
2002 Select DYRK1A Inhibitors Enhance Both Proliferation and Differentiation in Human Pancreatic Beta Cells
Wang, P.; Wood, O.; Choleva, L.; Liu, H.; Karakose, E.; Lambertini, L.; Pillard, A.; Wu, V.; Garcia-Ocana, A.; Scott, D. K.; Kumar, K.; DeVita, R. J.; Stewart, A. F.
10.1101/2024.05.17.594179 — molecular biology — Posted on 2024-05-17
2003 Bacterial sensor evolved by decreasing complexity
Monteagudo-Cascales, E.; Gavira, J. A.; Xing, J.; Velando, F.; Matilla, M. A.; Jouline, I.; Krell, T.
10.1101/2024.05.17.594639 — microbiology — Posted on 2024-05-17
2004 Microbial education plays a crucial role in harnessing the beneficial properties of microbiota for infectious disease protection in Crassostrea gigas
Dantan, L.; Carcassonne, P.; Degremont, L.; Morga, B.; Travers, M.-A.; Petton, B.; Mege, M.; Maurouard, E.; Allienne, J.-F.; Courtay, G.; Romatif, O.; Pouzadoux, J.; Lami, R.; Intertaglia, L.; Gueguen, Y.; Vidal-Dupiol, J.; Toulza, E.; Cosseau, C.
10.1101/2024.05.17.594303 — microbiology — Posted on 2024-05-17
2005 Fungal pathogens exposed - genomic and phenotypic insights into Candida auris and its relatives of the Candida haemulonii species complex
de Jong, A. W.; Boden, S.; Zandijk, A.; Kortsinoglou, A.; Gerrits van den Ende, B.; Francisco, E.; Podimata, K. N.; Kouvelis, V. N.; Zhou, M.; Hagen, F.
10.1101/2024.05.16.594571 — microbiology — Posted on 2024-05-17
2007 Emergence and evolution of heterocyte glycolipid biosynthesis enabled specialized nitrogen fixation in cyanobacteria
Ruth Perez Gallego, R.; von Meijenfeldt, F. A. B.; Bale, N. J.; Sinninghe Damste, J.; Villanueva, L.
10.1101/2024.05.17.594646 — microbiology — Posted on 2024-05-17
2008 Anaerobiosis modulates the performance of antimicrobial resistance genes in Enterobacteriaceae
Ortiz, L.; Prieto, A.; Kieffer, N.; Vergara, E.; Canton, R.; San Millan, A.; Baquero, F.; Hipolito, A.; Escudero, J. A.
10.1101/2024.05.17.594675 — microbiology — Posted on 2024-05-17
2010 Hydrocarbon-degrading microbial populations in permanently cold deep-sea sediments in the NW Atlantic
Adebayo, O.; Bhatnagar, S.; Webb, J.; Campbell, C.; Fowler, M.; MacAdam, N.; MacDonald, A.; Li, C.; Hubert, C. R.
10.1101/2024.05.16.593224 — microbiology — Posted on 2024-05-17
2011 Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles
Zheng, X.; Yu, S.; Zhou, Y.; Yu, K.; Gao, Y.; Chen, M.; Duan, D.; Li, Y.; Cui, X.; Mou, J.; Yang, Y.; Wang, X.; Chen, M.; Jiu, Y.; Zhao, J.; Meng, G.
10.1101/2024.05.16.594569 — immunology — Posted on 2024-05-17
2012 CD4 T cells and CD8α+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques
Simonson, A. W.; Zeppa, J. J.; Bucsan, A. N.; Chao, M. C.; Pokkali, S.; Hopkins, F.; Chase, M. R.; Vickers, A. J.; Sutton, M. S.; Winchell, C. G.; Myers, A. J.; Ameel, C. L.; Kelly, R.; Krouse, B.; Hood, L. E.; Li, J.; Lehman, C. C.; Kamath, M.; Tomko, J.; Rodgers, M. A.; Donlan, R.; Chishti, H.; Borish, H. J.; Klein, E.; Scanga, C. A.; Fortune, S.; Lin, P. L.; Maiello, P.; Roederer, M.; Darrah, P. A.; Seder, R. A.; Flynn, J. L.
10.1101/2024.05.14.594183 — immunology — Posted on 2024-05-17
2014 Diverse plant RNAs coat Arabidopsis leaves and are distinct from apoplastic RNAs
Borniego, L.; Singla-Rastogi, M.; Baldrich, P.; Sampangi-Ramaiah, M. H.; Zand Karimi, H.; McGregor, M.; Meyers, B.; Innes, R. W.
10.1101/2024.05.15.594325 — plant biology — Posted on 2024-05-17
2019 A chromosome region linked to neurodevelopmental disorders acts in distinct neuronal circuits in males and females to control locomotor behavior
Kim, J.; Vanrobaeys, Y.; Davatolhagh, F.; kelvington, b.; Chatterjee, S.; Ferri, S. L.; Angelakos, C.; Mills, A. A.; Fuccillo, M. V.; nickl-Jockschat, T.; Abel, T.
10.1101/2024.05.17.594746 — neuroscience — Posted on 2024-05-17
2020 Epidural Spinal Cord Recordings (ESRs): Sources of Artifact in Stimulation Evoked Compound Action Potentials
Deshmukh, A.; Settell, M. L.; Cheng, K. L.; Knudsen, B.; Trevathan, J. K.; LaLuzerne, M.; Blanz, S.; Skubal, A.; Verma, N.; Romanauski, B.; Brucker-Hahn, M.; Lam, D.; Lavrov, I.; Suminski, A.; Weber, D.; Fisher, L.; Lempka, S.; Shoffstall, A.; Park, H.; Ross Ellison, E.; Zhang, M.; Ludwig, K.
10.1101/2024.05.17.594739 — neuroscience — Posted on 2024-05-17
2023 Comparison of MR coil options for concurrent TMS-fMRI
Jackson, J. B.; Scrivener, C. L.; Mada, M.; Woolgar, A.
10.1101/2024.05.15.594454 — neuroscience — Posted on 2024-05-17
2025 Examining speech-brain tracking during early bidirectional, free-flowing caregiver-infant interactions
Phillips, E.; Goupil, L.; Ives, J.; Labendzki, P.; Whitehorn, M.; Marriott Haresign, I.; Wass, S.
10.1101/2024.05.16.594544 — neuroscience — Posted on 2024-05-17
2026 Anterior pituitary gland volume mediates associations between pubertal hormones and changes in transdiagnostic symptoms in youth
Picci, G.; Petro, N. M.; Casagrande, C. C.; Ott, L. R.; Okelberry, H. J.; Rice, D. L.; Coutant, A. T.; Ende, G. C.; Steiner, E. L.; Wang, Y.-P.; Stephen, J. M.; Calhoun, V. D.; Wilson, T. W.
10.1101/2024.05.17.594766 — neuroscience — Posted on 2024-05-17
2028 Brain-wide functional connectome analysis of 40,000 individuals reveals brain networks that show aging effects in older adults
Pan, Y.; Bi, C.; Kochunov, P.; Shardell, M.; Smith, J. C.; McCoy, R. G.; Ye, Z.; Yu, J.; Lu, T.; Yang, Y.; Lee, H.; Liu, S.; Gao, S.; Ma, Y.; Li, Y.; Chen, C.; Ma, T.; Wang, Z.; Nichols, T.; Hong, L. E.; Chen, S.
10.1101/2024.05.17.594743 — neuroscience — Posted on 2024-05-17
2039 Scalable Production and Purification of Engineered ARRDC1-Mediated Microvesicles in a HEK293 Suspension Cell System
Luther, K.; Navaei, A.; Gens, L.; Semple, C.; Moharil, P.; Passalacqua, I.; Vyas, K.; Wang, Q.; Liu, S.-L.; Sun, L.; Ramaswamy, S.; Zocco, D.; Nabhan, J.
10.1101/2024.05.14.594090 — bioengineering — Posted on 2024-05-17
2040 Gene regulatory dynamics during the development of a paleopteran insect, the mayfly Cloeon dipterum
Pallares-Albanell, J.; Ortega-Flores, L.; Senar-Serra, T.; Ruiz, A.; Abril, J. F.; Rossello, M.; Almudi, I.
10.1101/2024.05.14.594094 — genomics — Posted on 2024-05-17
2041 The Hippo-YAP/TAZ-TEAD axis promotes multipotency in bone marrow stromal cells
Cheng, Y.-H.; Chan, C. H. R.; Bian, Q.; Merling, R. K.; Kuznetsov, S. A.; Robey, P. G.; Cahan, P.
10.1101/2024.05.14.594149 — genomics — Posted on 2024-05-17
2044 Near real-time monitoring of long legged wading birds using uncrewed aircraft systems and computer vision
White, E. P.; Garner, L.; Weinstein, B.; Senyondo, H.; Ortega, A.; Steinkraus, A.; Yenni, G. M.; Frederick, P.; Ernest, S. M.
10.1101/2024.05.14.594154 — ecology — Posted on 2024-05-17
2047 Quantitative imaging of species-specific lipid transport in mammalian cells
Iglesias-Artola, J. M.; Schumann, K.; Bohlig, K.; Lennartz, H. M.; Schumacher, M.; Barahtjan, P.; Jiminez Lopez, C.; Sachl, R.; Pombo-Garcia, K.; Lohmann, A.; Riegerova, P.; Hof, M.; Drobot, B.; Shevchenko, A.; Honigmann, A.; Nadler, A.
10.1101/2024.05.14.594078 — cell biology — Posted on 2024-05-17
2048 Ebola virus infection of Flt3-dependent, conventional dendritic cells and antigen cross-presentation leads to high levels of T-cell activation
Niemetz, L. R.; Bodmer, B. S.; Olal, C.; Escudero-Perez, B.; Hoehn, K.; Bencsik, A.; Vickers, M. A.; Rodriguez, E.; Oestereich, L.; Hoenen, T.; Munoz-Fontela, C.
10.1101/2024.05.14.594125 — immunology — Posted on 2024-05-17
2049 Feminization of the precarious at the UNAM: examining obstacles to gender equality
ciccia, l.; Espinosa Lugo, G.; Garcia Guzman, G.; Gasca-Pineda, J.; Velez, P.; Espinosa Asuar, L.
10.1101/2024.05.13.593992 — scientific communication and education — Posted on 2024-05-17
2050 Arabidopsis ABCC4 encodes a cytokinin efflux transporter and is involved in root system development
Uragami, T.; Kiba, T.; Kojima, M.; Takebayashi, Y.; Tozawa, Y.; Hayashi, Y.; Kinoshita, T.; Sakakibara, H.
10.1101/2024.05.14.594121 — plant biology — Posted on 2024-05-17
2052 Selective molecular inhibition of the HDAC6 ZnF-UBP binding domain impairs multiple myeloma cell proliferation
Rincon, R.; Coira, I. F.; Richieu, A.; Attana, F.; Urwyler, M.; Haider, S.; Bourquin, C.; Bertrand, P.; Cuendet, M.
10.1101/2024.05.14.594071 — cancer biology — Posted on 2024-05-17
2058 Intercellular extrachromosomal DNA copy number heterogeneity drives cancer cell state diversity
Stoeber, M. C.; Chamorro Gonzalez, R.; Brueckner, L.; Conrad, T.; Wittstruck, N.; Szymansky, A.; Eggert, A.; Schulte, J. H.; Koche, R. P.; Henssen, A. G.; Schwarz, R. F.; Haase, K.
10.1101/2023.01.21.525014 — cancer biology — Posted on 2024-05-17
2060 Individual tree crown maps for the National Ecological Observatory Network
Weinstein, B.; Marconi, S.; Zare, A.; Bohlman, S.; Singh, A.; Graves, S. J.; Magee, L.; Johnson, D. J.; Record, S.; Rubio, V. E.; Swenson, N. G.; Veblen, T.; Townsend, P.; Andrus, R. A.; White, E. P.
10.1101/2023.10.25.563626 — ecology — Posted on 2024-05-17
2061 A mitochondria-targeted PPR protein restores cytoplasmic male sterility by post-transcriptional modification of ORF147 in Cajanus cajanifolius
Bhattacharya, J.; Nitnavare, R. B.; Yeshvekar, R.; Reddy, D. S.; Sapara, V.; Reddy, P.; Ramtirtha, Y.; Kalenhalli, Y.; Mathur, P. B.; Reddy, P. S.
10.1101/2024.05.17.594745 — developmental biology — Posted on 2024-05-17
2063 Electrophysiological correlates of visual memory search
Williams, L. H.; Wiegand, I.; Lavelle, M.; Wolfe, J. M.; Peelen, M. V.; Fukuda, K.; Drew, T.
10.1101/2024.05.17.594466 — neuroscience — Posted on 2024-05-17
2064 Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI
Autio, J. A.; Kimura, I.; Ose, T.; Matsumoto, Y.; Ohno, M.; Urushibata, Y.; Ikeda, T.; Glasser, M. F.; Van Essen, D. C.; Hayashi, T.
10.1101/2024.05.16.594068 — neuroscience — Posted on 2024-05-17
2066 Developmental olfactory dysfunction and abnormal odor memory in immune-challenged Disc1+/- mice
Parbst, F.; Kostka, J. K.; Gunther, A.; Chen, Y.-N.; Hanganu-Opatz, I. L. H.; Bitzenhofer, S. H.
10.1101/2024.05.17.594663 — neuroscience — Posted on 2024-05-17
2067 TMS-based neurofeedback training of mental finger individuation induces neuroplastic changes in the sensorimotor cortex
Odermatt, I. A.; Schulthess-Lutz, M.; Mihelj, E.; Howell, P.; Heimhofer, C. C.; McMackin, R.; Ruddy, K.; Freund, P.; Kikkert, S.; Wenderoth, N.
10.1101/2024.05.16.594100 — neuroscience — Posted on 2024-05-17
2068 High delay discounting relates to core symptoms and to pulvinar atrophy in frontotemporal dementia
Godefroy, V.; Durand, A.; Levy, R.; Batrancourt, B.; Schmidt, L.; Koban, L.; Plassmann, H.
10.1101/2024.05.16.594526 — neuroscience — Posted on 2024-05-17
2069 Valence ambiguity dynamically shapes striatal dopamine heterogeneity
Bornhoft, K. N.; Prohofsky, J.; O'Neal, T. J.; Wolff, A. R.; Saunders, B. T.
10.1101/2024.05.17.594692 — neuroscience — Posted on 2024-05-17
2072 Assessing the Adequacy of Morphological Models used in Palaeobiology
Mulvey, L. P. A.; May, M. R.; Brown, J. M.; Hoehna, S.; Wright, A. M.; Warnock, R. C. M.
10.1101/2024.01.25.577179 — paleontology — Posted on 2024-05-17
2074 The differential effect of optogenetic serotonergic manipulation on sustained motor actions and stationary waiting for future rewards in mice
Taira, M.; Miyazaki, K. W.; Miyazaki, K.; Chen, J.; Okitsu-Sakurayama, S.; Chaudhary, A.; Nishio, M.; Miyake, T.; Yamanaka, A.; Tanaka, K. F.; Doya, K.
10.1101/2024.05.17.594118 — animal behavior and cognition — Posted on 2024-05-17
2076 Optokinetic response in D. Melanogaster reveals the nature of common repellent odorants.
Menti, G. M.; Bruzzone, M.; Visentin, P.; Drago, A.; Zordan, M. A.; Dal Maschio, M.; Megighian, A.
10.1101/2024.05.17.594662 — animal behavior and cognition — Posted on 2024-05-17
2077 Development of shell field populations in gastropods
Phuangphong, S.; Yoshikawa, H.; Kojima, Y.; Wada, H.; Morino, Y.
10.1101/2024.05.16.592602 — developmental biology — Posted on 2024-05-17
2078 Deep-Tissue Spatial Omics: Imaging Whole-Embryo Transcriptomics and Subcellular Structures at High Spatial Resolution
Gandin, V.; Kim, J.; Yang, L.-Z.; Lian, Y.; Kawase, T.; Hu, A.; Rokicki, K.; Fleishman, G.; Tillberg, P.; Aguilera Castrejon, A.; Stringer, C.; Preibisch, S.; Liu, Z. J.
10.1101/2024.05.17.594641 — developmental biology — Posted on 2024-05-17
2079 Vascular development of fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa.
Sobierajski, E.; Czubay, K.; Beemelmans, C.; Beemelmans, C.; Meschkat, M.; Uhlenkamp, D.; Meyer, G.; Wahle, P.
10.1101/2024.05.17.594685 — developmental biology — Posted on 2024-05-17
2082 Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface device
Jung, T.; Zeng, N.; Fabbri, J. D.; Eichler, G.; Li, Z.; Willeke, K.; Wingel, K. E.; Dubey, A.; Huq, R.; Sharma, M.; Hu, Y.; Ramakrishnan, G.; Tien, K.; Mantovani, P.; Parihar, A.; Yin, H.; Oswalt, D.; Misdorp, A.; Uguz, I.; Shinn, T.; Rodriguez, G. J.; Nealley, C.; Gonzales, I.; Roukes, M.; Knecht, J.; Yoshor, D.; Canoll, P.; Spinazzi, E.; Carloni, L. P.; Pesaran, B.; Patel, S.; Youngerman, B.; Cotton, R. J.; Tolias, A.; Shepard, K. L.
10.1101/2024.05.17.594333 — neuroscience — Posted on 2024-05-17
2084 Glial cell activation precedes neurodegeneration in the cerebellar cortex of the YG8-800 murine model of Friedreich's ataxia
Vicente-Acosta, A.; Herranz-Martin, S.; Pazos, M. R.; Galan-Cruz, J.; Amores, M.; Loria, F.; Diaz-Nido, J.
10.1101/2024.05.17.594658 — neuroscience — Posted on 2024-05-17
2087 Optical constraints on two-photon voltage imaging
Brooks, F. P.; Davis, H. C.; Wong-Campos, J. D.; Cohen, A. E.
10.1101/2023.11.18.567441 — neuroscience — Posted on 2024-05-17
2088 Imaging demyelinated axons after spinal cord injuries with PET tracer 3F4AP
Ramos-Torres, K. M.; Conti, S.; Zhou, Y.-P.; Tiss, A.; Caravagna, C.; Takahashi, K.; He, M.; Wilks, M. Q.; Eckl, S.; Sun, Y.; Biundo, J.; Gong, K.; He, Z.; Linnman, C.; Brugarolas, P.
10.1101/2024.04.24.590984 — neuroscience — Posted on 2024-05-17
2089 Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations
Ghandian, S.; Albarghouthi, L.; Nava, K.; Sharma, S. R. R.; Minaud, L.; Beckett, L.; Saito, N.; DeCarli, C.; Rissman, R. A.; Teich, A. F.; Jin, L.-W.; Dugger, B. N.; Keiser, M. J.
10.1101/2024.05.15.594372 — pathology — Posted on 2024-05-17
2090 EZH2-driven immune evasion defines high-risk pediatric AML with t(16;21) FUS::ERG gene fusion.
Buteyn, N. J.; Burke, C. G.; Sartori, V. J.; Deering-Gardner, E.; DeBruine, Z. J.; Kamarudin, D.; Chandler, D. P.; Monovich, A. C.; Perez, M. W.; Yi, J. S.; Ries, R. E.; Alonzo, T. A.; Ryan, R. J.; Meshinchi, S.; Triche, T. J.
10.1101/2024.05.14.594150 — cancer biology — Posted on 2024-05-17
2091 Imaging of MAP kinase dynamics reveals endocytic regulation of pulsatile signalling and network re-wiring in response to targeted therapy in EGFR-mutant non-small cell lung cancer
Le Marois, A. M. I.; Bailey, S.; Hooper, S.; Kumar, S.; Sparks, H.; Alexandrov, Y.; Caswell, D. R.; Fröhlich, F.; Schlegelmilch, K.; Valand, K.; Martin, M. J.; Narvaez, A. J.; Swanton, C.; Downward, J.; Dunsby, C.; French, P. M.; Sahai, E.
10.1101/2024.05.14.594112 — cancer biology — Posted on 2024-05-17
2093 Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in situ
Li, Y.; Arghittu, S. M.; Dietz, M. S.; Hella, G. J.; Hasse, D.; Ferraris, D. M.; Freund, P.; Barth, H.-D.; Niemann, H. H.; Covino, R.; Heilemann, M.
10.1101/2023.12.22.572978 — biophysics — Posted on 2024-05-17
2096 Clonal expansion dictates the efficacy of mitochondrial lineage tracing in single cells
Wang, X.; Wang, K.; Zhang, W.; Tang, Z.; Zhang, H.; Cheng, Y.; Zhou, D.; Zhang, C.; Zhong, W.-Z.; Ma, Q.; Xu, J.; Hu, Z.
10.1101/2024.05.15.594338 — bioinformatics — Posted on 2024-05-17
2097 CellAgent: An LLM-driven Multi-Agent Framework for Automated Single-cell Data Analysis
Xiao, Y.; Liu, J.; Zheng, Y.; Xie, X.; Hao, J.; Li, M.; Wang, R.; Ni, F.; Li, Y.; Luo, J.; Jiao, S.; Peng, J.
10.1101/2024.05.13.593861 — bioinformatics — Posted on 2024-05-17
2098 Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
Xiang, G.; He, X.; Giardine, B. M.; Isaac, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D. M.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.
10.1101/2023.04.02.535219 — genomics — Posted on 2024-05-17
2099 A scenario for an evolutionary selection of ageing
Roget, T.; Macmurray, C.; Jolivet, P.; Meleard, S.; Rera, M.
10.1101/2022.03.11.483978 — evolutionary biology — Posted on 2024-05-17
2103 SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription
Li, J.; Li, L.; Smith-Fry, K.; Wilmot, Z. F.; Carroll, L.; Morrison, L.; Ge, X.; Nelson, M.; Hill, L. A.; Zhang, X.; Nielsen, T. O.; Hirst, M.; Underhill, T. M.; Cairns, B.; Jones, K. B.
10.1101/2024.05.14.594253 — cancer biology — Posted on 2024-05-17
2106 Synovial Sarcoma Chromatin Dynamics Reveal a Continuum in SS18:SSX Reprograming
Hofvander, J.; Qiu, A.; Lee, K.; Bilenky, M.; Carles, A.; Cao, Q.; Moksa, M.; Steif, J.; Su, E.; Sotiriou, A.; Goytain, A.; Hill, L.; Singer, S.; Andulis, I.; Wunder, J.; Mertens, F.; Banito, A.; Jones, K. B.; Underhill, T. M.; Nielsen, T.; Hirst, M.
10.1101/2024.05.14.594262 — cancer biology — Posted on 2024-05-17
2108 MetaDAG: a web tool to generate and analysemetabolic networks
Palmer-Rodriguez, P. A.; Alberich, R.; Reyes-Prieto, M. B.; Castro, J. A.; Llabres Segura, M.
10.1101/2024.05.15.593827 — bioinformatics — Posted on 2024-05-17
2109 Immunopipe: A comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline
Wang, P.; Yu, Y.; Dong, H.; Zhang, S.; Sun, Z.; Zeng, H.; Mondello, P.; Kocher, J.-P.; Wang, J.-W.; Asmann, Y. W.; Lin, Y.; Li, Y.
10.1101/2024.05.14.594248 — bioinformatics — Posted on 2024-05-17
2111 Diverging Arabidopsis populations quickly accumulate pollen-acting genetic incompatibilities
Condon, C.; Carpentier, F.; Tabourin, M.; Wozniak, N.; Takou, M.; Blassiau, C.; Kumar, V.; Pietzenuk, B.; Habert, R.; de Meaux, J.; Kraemer, U.; Roux, C.; Corbett-Detig, R.; Castric, V.
10.1101/2024.05.14.594187 — genomics — Posted on 2024-05-17
2112 An epilepsy-associated CILK1 variant compromises KATNIP regulation and impairs primary cilia and Hedgehog signaling
Limerick, A.; McCabe, E. A.; Turner, J. S.; Kuang, K. W.; Brautigan, D. L.; Hao, Y.; Chu, C.; Fu, S.; Ahmadi, S.; Xu, W.; Fu, Z.
10.1101/2024.05.14.594243 — cell biology — Posted on 2024-05-17
2113 Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Response
Malhi, N. K.; Luo, Y.; Tang, X.; Chadha, R. S.; Tapia, A.; Liu, X.; Chen, M.; Yuan, D.; Qi, M.; Wei, L.; Cooke, J. P.; Natarajan, R.; Southerland, K. W.; Chen, Z. B.
10.1101/2024.05.14.594235 — cell biology — Posted on 2024-05-17
2114 The autophagy-related genes AtATG5 and AtATG7 influence reserve mobilisation and responses to ABA during seed germination in Arabidopsis thaliana
Contreras, E.; Pastor-Mora, E.; Aylon-Rodriguez, M.; Gonzalez-Ceballos, M.; Delgado-Gutierrez, M. A.; Sanchez-Vicente, I.; Lorenzo, O.; Vicente-Carbajosa, J.; Iglesias-Fernandez, R.
10.1101/2024.05.15.593177 — plant biology — Posted on 2024-05-17
2115 High-throughput Phenotyping of Soybean Biomass: Conventional Trait Estimation and Novel Latent Feature Extraction Using UAV Remote Sensing and Deep Learning Models
Okada, M.; Barras, C.; Toda, Y.; Hamazaki, K.; Ohmori, Y.; Yamasaki, Y.; Takahashi, H.; Takanashi, H.; Tsuda, M.; Yokota Hirai, M.; Tsujimoto, H.; Kaga, A.; Nakazono, M.; Fujiwara, T.; Iwata, H.
10.1101/2024.05.14.594109 — plant biology — Posted on 2024-05-17
2117 Impact of long-term rapamycin treatment on age-related osteoarthritis in common marmoset
Minton, D. M.; Ailiani, A. R.; Focht, M. D. K.; Kersh, M. E.; Marolf, A. J.; Santangelo, K. S.; Salmon, A. B.; Konopka, A. R.
10.1101/2024.05.14.594256 — physiology — Posted on 2024-05-17
2118 Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by reprogramming macrophages and increasing UCP1 expression in vascular smooth muscle cells
Stachowicz, A.; Wisniewska, A.; Czepiel, K.; Pomierny, B.; Skorkowska, A.; Kusnierz-Cabala, B.; Surmiak, M.; Kus, K.; Wood, M. E.; Torregrossa, R.; Whiteman, M.; Olszanecki, R.
10.1101/2024.05.15.594319 — pharmacology and toxicology — Posted on 2024-05-17
2123 GeoAB: Towards Realistic Antibody Design and Reliable Affinity Maturation
LIN, H.; Wu, L.; Yufei, H.; Liu, Y.; Zhang, O.; Zhou, Y.; Sun, R.; Li, S. Z.
10.1101/2024.05.15.594274 — bioinformatics — Posted on 2024-05-17
2124 Clinical considerations on antimicrobial resistance potential of complex microbiological samples
Solymosi, N.; Toth, A. G.; Nagy, S. A.; Csabai, I.; Feczko, C.; Reibling, T.; Nemeth, T.
10.1101/2024.05.14.594174 — genomics — Posted on 2024-05-17
2125 From gene to structure: Unraveling genomic dark matter in Ca. Accumulibacter
Xie, X.; Deng, X.; Chen, L.; Yuan, J.; Chen, H.; Wei, C.; Feng, C.; Liu, X.; Qiu, G.
10.1101/2024.05.14.594254 — genomics — Posted on 2024-05-17
2128 Comparative genomic analysis identifies potential adaptive variation and virulence factors in Mycoplasma ovipneumoniae
Andrews, K. R.; Besser, T. E.; Stalder, T.; Top, E. M.; Baker, K. N.; Fagnan, M. W.; New, D. D.; Schneider, G. M.; Gal, A.; Andrews-Dickert, R.; Hunter, S. S.; Beckmen, K. B.; Christensen, L.; Justice-Allen, A.; Konetchy, D.; Lehman, C. P.; Manlove, K.; Miyasaki, H.; Nordeen, T.; Roug, A.; Cassirer, E. F.
10.1101/2024.05.14.594237 — evolutionary biology — Posted on 2024-05-17
2130 Tissue growth associated transition of podoplanin-expressing stromal cells in the postnatal mouse femur
Notoh, H.; Nara, R.; Suzuki, N.; Suzuki, A.; Okamoto, S.; Tsukiji, N.; Kanematsu, T.; Suzuki, N.; Katsumi, A.; Kojima, T.; Suzuki-Inoue, K.; Matsushita, T.; Tamura, S.
10.1101/2024.05.15.593859 — cell biology — Posted on 2024-05-17
2132 Reduced glucose supply during neonatal infection attenuates neurological and renal pathology via modulation of innate and Th1 immunity
Zhong, J.; Baek, O.; Doughty, R.; Joergensen, B. M.; Jensen, H. E.; Thymann, T.; Sangild, P. T.; Brunse, A.; Nguyen, D. N.
10.1101/2024.05.15.594288 — immunology — Posted on 2024-05-17
2133 TbpB-based oral mucosal vaccine provides heterologous protection against Glasser disease caused by different serovars of Spanish field isolates of Glaesserella parasuis
Gonzalez-Fernandez, A.; Mencia-Ares, O.; Garcia-Iglesias, M. J.; Petrocchi-Rilo, M.; Miguelez-Perez, R.; Perello Jimenez, A.; Herencia-Lagunar, E.; Acebes-Fernandez, V.; Gutierrez-Martin, C. B.; Martinez-Martinez, S.
10.1101/2024.05.15.594294 — immunology — Posted on 2024-05-17
2136 Mechanics of knee meniscus results from precise balance between material microstructure and synovial fluid viscosity
Afanador, C. A. S.; Urcun, S.; Sbalzarini, I. F.; Bordas, S. P. A.; Barrera, O.; Rajabi, M. M.; Seil, R.; Obeidat, A.
10.1101/2024.05.15.594315 — bioengineering — Posted on 2024-05-17
2138 Bam complex associated proteins in Escherichia coli are functionally linked to peptidoglycan biosynthesis, membrane fluidity and DNA replication
Bryant, J. A.; Staunton, K. A.; Doherty, H. M.; Alao, M. B.; Ma, X.; Morcinek-Orlowska, J.; Goodall, E. C. A.; Gray, J.; Milner, M.; Cole, J. A.; de Cogan, F.; Knowles, T. J.; Glinkowska, M. K.; Moradigaravand, D.; Henderson, I. R.; Banzhaf, M.
10.1101/2023.07.05.547807 — microbiology — Posted on 2024-05-17
2139 Cell type-specific gene expression dynamics during human brain maturation
Steyn, C.; Mishi, R.; Fillmore, S.; Verhoog, M. B.; More, J.; Rohlwink, U. K.; Melvill, R.; Butler, J.; Enslin, J. M. N.; Jacobs, M.; Sauka-Spengler, T.; Greco, M.; Quinones, S.; Dulla, C. G.; Raimondo, J. V.; Figaji, A.; Hockman, D.
10.1101/2023.09.29.560114 — neuroscience — Posted on 2024-05-17
2145 ProSST: Protein Language Modeling with Quantized Structure and Disentangled Attention
Li, M.; Tan, Y.; Ma, X.; Zhong, B.; Zhou, Z.; Yu, H.; Ouyang, W.; Hong, L.; Zhou, B.; Tan, P.
10.1101/2024.04.15.589672 — bioinformatics — Posted on 2024-05-17
2147 Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM
Valerie, N. C. K.; Sanjiv, K.; Mortusewicz, O.; Zhang, S. M.; Alam, S.; Pires, M. J.; Stigsdotter, H.; Rasti, A.; Langelier, M.-F.; Rehling, D.; Throup, A.; Desroses, M.; Onireti, J.; Wakchaure, P.; Almlof, I.; Bostrom, J.; Bevc, L.; Benzi, G.; Stenmark, P.; Pascal, J. M.; Helleday, T.; Page, B. D. G.; Altun, M.
10.1101/2022.09.19.505646 — biochemistry — Posted on 2024-05-17
2149 Detecting population continuity and ghost admixture among ancient genomes
McKenna, J.; Sjodin, P.; Bernhardsson, C.; Waxman, D.; Jakobsson, M.
10.1101/2022.12.01.518676 — genetics — Posted on 2024-05-17
2153 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Naik, A.; Chang, A. N.; Miller, R. T.
10.1101/2024.02.26.582201 — cell biology — Posted on 2024-05-17
2154 Hemin-induced platelet activation is regulated via ACKR3 chemokine surface receptor - implications for passivation of vulnerable atherosclerotic plaque
Laspa, Z.; Dicenta-Baunach, V.; Schaale, D.; Sigle, M.; Hochuli, R.; Castor, T.; Bayrak, A.; Harm, T.; Mueller, K. A. L.; Pillaiyar, T.; Laufer, S.; Rohlfing, A.-K.; Gawaz, M.
10.1101/2024.05.13.593847 — cell biology — Posted on 2024-05-17
2155 CemR atypical response regulator impacts energy conversion in Campylobacteria
Noszka, M.; Strzalka, A.; Muraszko, J.; Hofreuter, D.; Abele, M.; Ludwig, C.; Stingl, K.; Pawlik, A. M.
10.1101/2024.03.07.583886 — molecular biology — Posted on 2024-05-17
2156 Rhizospheric miRNAs affect the plant microbiota
Middleton, H.; Dozois, J. A.; Monard, C.; Daburon, V.; Clostres, E.; Tremblay, J.; Combier, J.-P.; Yergeau, E.; El-Amrani, A.
10.1101/2022.07.26.501597 — microbiology — Posted on 2024-05-17
2157 Spontaneous human CD8 T cell and EAE-inducible human CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB1*15-positive multiple sclerosis PBMC humanized mice
Papazian, I.; Kourouvani, M.; Dagkonaki, A.; Gouzouasis, V.; Dimitrakopoulou, L.; Markoglou, N.; Badounas, F.; Tselios, T.; Anagnostouli, M.; Probert, L.
10.1101/2023.06.07.543414 — immunology — Posted on 2024-05-17
2160 Can we improve slow learning in cerebellar patients?
Hulst, T.; Mamlins, A.; Frens, M.; Chang, D.-I.; Goericke, S. L.; Timmann, D.; Donchin, O.
10.1101/2020.07.03.185959 — neuroscience — Posted on 2024-05-17
2161 Alternative splicing across the C. elegans nervous system
Weinreb, A.; Varol, E.; Barrett, A.; McWhirter, R. M.; Taylor, S. R.; Courtney, I.; Basavaraju, M.; Poff, A.; Tipps, J. A.; Collings, B.; The CeNGEN Consortium, ; Krishnaswamy, S.; Miller, D. M.; Hammarlund, M.
10.1101/2024.05.16.594567 — neuroscience — Posted on 2024-05-17
2162 Integrating stereotypes and factual evidence in interpersonal communication
Koch, S. B. J.; Tyborowska, A.; Niermann, H. C. M.; Cillessen, A. H. N.; Roelofs, K.; Basnakova, J.; Toni, I.; Stolk, A.
10.1101/2023.05.23.540979 — neuroscience — Posted on 2024-05-17
2163 Integrated combinatorial functional genomics and spatial transcriptomics of tumors decodes genotype to phenotype relationships
Breinig, M.; Lomakin, A.; Heidari, E.; Ritter, M.; Rukhovich, G.; Boese, L.; Butthof, L.; Wendler-Link, L.; Wiethoff, H.; Poth, T.; Sahm, F.; Schirmacher, P.; Stegle, O.; Gerstung, M.; Tschaharganeh, D.
10.1101/2024.05.14.593940 — cancer biology — Posted on 2024-05-17
2164 Annotation-Free Deep Learning for Predicting Gene Mutations from Whole Slide Images of Acute Myeloid Leukemia
Wei, B.-H.; Tsai, X. C.-H.; Sun, K.-J.; Lo, M.-Y.; Hung, S.-Y.; Chou, W.-C.; Tien, H.-F.; Hou, H.-A.; Chen, C.-Y.
10.1101/2023.11.13.563550 — bioinformatics — Posted on 2024-05-17
2165 Genomic loss of GPR108 disrupts AAV transduction in birds
Nevue, A. A.; Sairavi, A.; Huang, S. J.; Nakai, H.; Mello, C. V.
10.1101/2024.05.16.589954 — genomics — Posted on 2024-05-17
2166 A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma
Pilcher, W. C.; Yao, L.; Gonzalez-Kozlova, E.; Pita-Juarez, Y.; Karagkouni, D.; Acharya, C.; Michaud, M. E.; Hamilton, M.; Nanda, S.; Song, Y.; Sato, K.; Wang, J. T.; Satpathy, S.; Ma, Y.; Schulman, J.; D'Souza, D.; Jayasinghe, R. G.; Cheloni, G.; Bakhtiari, M.; Pabustan, N.; Nie, K.; Foltz, J. A.; Saldarriaga, I.; Alaaeldin, R.; Lepisto, E.; Chen, R.; Fiala, M. A.; Thomas, B. E.; Cook, A.; Vieira Dos Santos, J.; Chiang, I.-l.; Figueiredo De Souza, I.; Fortier, J.; Slade, M.; Oh, S. T.; Rettig, M. P.; Anderson, E.; Li, Y.; Dasari, S.; Strausbauch, M. A.; Simon, V. A.; MMRF Immune Atlas Consort
10.1101/2024.05.15.593193 — genomics — Posted on 2024-05-17
2168 Role of Lamin A/C on dendritic cell function in antiviral immunity
Herrero-Fernandez, B.; Gomez-Bris, R.; Ortega-Zapero, M.; Saez, A.; Iborra, S.; Zorita, V.; Quintas, A.; Vazquez, E.; Dopazo, A.; Sanchez-Madrid, F.; Arribas, S. M.; Gonzalez-Granado, J. M.
10.1101/2024.05.14.593747 — immunology — Posted on 2024-05-17
2169 An atlas of protein-protein associations of human tissues prioritizes candidate disease genes
Laman Trip, D. S.; van Oostrum, M.; Memon, D.; Frommelt, F.; Baptista, D.; Panneerselvam, K.; Bradley, G.; Licata, L.; Hermjakob, H.; Orchard, S.; Trynka, G.; McDonagh, E.; Fossati, A.; Aebersold, R.; Gstaiger, M.; Wollscheid, B.; Beltrao, P.
10.1101/2024.05.15.594301 — systems biology — Posted on 2024-05-17
2170 Heterotypic competition between cancer cells and hepatocytes generates heterogeneous context-dependent phenotypes
Spinazzola, A.; Carvalho, T.; Pinto, M. A. F.; Marques-Reis, M.; Gutierrez-Garcia, A.; Accardi, D.; Moreno, E.
10.1101/2024.05.15.593526 — cancer biology — Posted on 2024-05-17
2172 Monomer-dimer structural comparison in quinol-dependent nitric oxide reductase reveals a functional basis for superior enzymatic activity in the dimer
Gopalasingam, C. C.; Egami, H.; Shigematsu, H.; Sakaue, M.; Fukumoto, K.; Gerle, C.; Yamamoto, M.; Shiro, Y.; Muramoto, K.; Tosha, T.
10.1101/2024.05.16.593792 — biochemistry — Posted on 2024-05-17
2174 ProSST: Protein Language Modeling with Quantized Structure and Disentangled Attention
Li, M.; Tan, Y.; Ma, X.; Zhong, B.; Zhou, Z.; Yu, H.; Ouyang, W.; Hong, L.; Zhou, B.; Tan, P.
10.1101/2024.04.15.589672 — bioinformatics — Posted on 2024-05-17
2177 CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo
Vuong, L. M.; Hachey, S. J.; Shiu, J.; Xie, D. F.; Salvador, N.; Brindani, N.; Bertozzi, S. M.; Summa, M.; Bertorelli, R.; Armirotti, A.; Pham, R.; Ku, V. S.; Nguyen, T.; Choi, B.; Hughes, C. C.; De Vivo, M.; Ganesan, A. K.
10.1101/2024.04.09.588609 — cancer biology — Posted on 2024-05-16
2179 Neuronal phenotype defined by transcriptome-wide bursting kinetics in pyramidal and fast-spiking cells
Tukacs, V.; Fladhus, E. K.; Mittli, D.; Lorincz, M. L.; Eberwine, J.; Kekesi, K. A.; Juhasz, G.
10.1101/2024.05.16.594495 — bioinformatics — Posted on 2024-05-16
2181 Combinatorial characterization of bacterial taxa-driven differences in the microbiome of oyster reefs
Cyphert, E. L.; Nand, S.; Franco, G.; Hajkowski, M.; Soto, L.; Lee, D.; Ferner, M.; Zabin, C.; Blumenthal, J.; Deck, A.; Boyer, K.; Burrus, L.; Hernandez, C. J.; Anand, A.
10.1101/2024.05.15.594453 — microbiology — Posted on 2024-05-16
2182 Split minireporters facilitate monitoring of gene expression and peptide production in linear cell-free transcription-translation systems
Levrier, A.; Capin, J.; Mayonove, P.; Karpathakis, I.-I.; Voyvodic, P.; Devisch, A.; Zuniga, A.; Cohen-Gonsaud, M.; Cabantous, S.; Noireaux, V.; Bonnet, J.
10.1101/2024.05.16.594532 — synthetic biology — Posted on 2024-05-16
2183 Flawed machine-learning confounds coding sequence annotation
Champion, D.; Chen, T.-H.; Thomson, S.; Black, M. A.; Gardner, P. P.
10.1101/2024.05.16.594598 — bioinformatics — Posted on 2024-05-16
2184 Tracing Homopolymers in Oikopleura dioica's mitogenome
Dierckxsens, N.; Watanabe, K.; Tan, Y.; Masunaga, A.; Mansfield, M. J.; Miao, J.; Luscombe, N. M.; Plessy, C.
10.1101/2024.05.16.594446 — genomics — Posted on 2024-05-16
2185 Optimised in-solution enrichment of over a million ancient human SNPs
Davidson, R.; Roca-Rada, X.; Ravishankar, S.; Taufik, L.; Haarkötter, C.; Collen, E.; Webb, P.; Williams, M. P.; Mahmud, M. I.; Djami, E. N. I.; Purnomo, G. A.; Santos, C.; Malagosa, A.; Manzanilla, L. R.; Silva, A. M.; Tereso, S.; Matos, V.; Carvalho, P. C.; Fernandes, T.; Maurer, A.-F.; Teixeira, J. C.; Tobler, R.; Fehren-Schmitz, L.; Llamas, B.
10.1101/2024.05.16.594432 — genomics — Posted on 2024-05-16
2187 Ide copy number variant does not influence lesion size and mortality in two C57BL/6J mouse models of cerebrovascular ischemia nor in human cerebrovascular disease. An exploratory study
Sassi, C.; Foddis, M.; Blumenau, S.; Mueller, S.; Messerschmidt, C.; Rocca, C.; Pagnamenta, A. T.; Winek, K.; Endres, M.; Meisel, A.; Tucci, A.; Bras, J.; Guerreiro, R.; Beule, D.; Dirnagl, U.
10.1101/2024.05.15.593342 — genetics — Posted on 2024-05-16
2191 Efficient DNA base editing via an optimized DYW-like deaminase
Kweon, J.; Park, S.; Jeon, M. Y.; Lim, K.; Jang, G.; Jang, A.-H.; Lee, M.; Seok, C.; Lee, C.; Park, S.; Ahn, J.; Jang, J.; Sung, Y.; Kim, D.; Kim, Y.
10.1101/2024.05.15.594452 — molecular biology — Posted on 2024-05-16
2192 TRIM52 is a primate-specific player in the DNA repair process under tight proteolytic control by a triad of giant E3 ligases
Shulkina, A.; Hacker, K.; Ehrmann, J. F.; Budroni, V.; Mandlbauer, A.; Bock, J.; Grabarczyk, D. B.; Cochella, L.; Clausen, T.; Versteeg, G. A.
10.1101/2024.05.16.594269 — molecular biology — Posted on 2024-05-16
2193 Streptolysin O Accelerates the Conversion of Plasminogen to Plasmin
Tang, D.; Khakzad, H.; Hjortswang, E.; Malmström, L.; Ekström, S.; Happonen, L.; Malmström, J.
10.1101/2024.05.15.594458 — molecular biology — Posted on 2024-05-16
2194 SLAMseq reveals transfer of RNA from liver to kidney in the mouse
Hunter, R. W.; Sun, J.; Palmer, T.; Bailey, M. A.; Dhaun, N.; Buck, A.; Dear, J. W.
10.1101/2024.05.16.594511 — molecular biology — Posted on 2024-05-16
2195 A duplexed CRISPRi-based approach to predict synergistic antibiotic targets in Escherichia coli.
Xiong, X.; Furseth, H.; McCoy, B.; Slavic, L.; Yuan, X.; Chen, S.; Baughn, A. D.; Minato, Y.; Harcombe, W. R.
10.1101/2024.05.15.594409 — microbiology — Posted on 2024-05-16
2197 Inter-individual and inter-regional variability of breast milk antibody reactivity to bacterial lipopolysaccharides
Crone, L.; Sobek, J.; Mueller, N.; Restin, T.; Bassler, D.; Paganini, D.; Zimmermann, M. B.; Zarnovican, P.; Routier, F. H.; Romero-Urunuela, T.; Izquierdo, L.; Hennet, T.
10.1101/2024.05.16.594523 — microbiology — Posted on 2024-05-16
2198 Molecular basis for the host range function of the poxvirus PKR inhibitor E3
Haller, S. L.; Park, C.; Bruneau, R. C.; Megawati, D.; Zhang, C.; Vipat, S.; Peng, C.; Senkevich, T. G.; Brennan, G. J.; Tazi, L.; Rothenburg, S.
10.1101/2024.05.16.594589 — microbiology — Posted on 2024-05-16
2200 Self-cleaving ribozymes conserved in RNA viruses unveil a new role in protein translation
Lopez-Galiano, M. J.; Chiba, S.; Forgia, M.; Navarro, B.; Cervera, A.; Babaian, A.; Di Serio, F.; Turina, M.; De la Pena, M.
10.1101/2024.05.16.594327 — microbiology — Posted on 2024-05-16
2201 Exploring Probiotic Potential: A Comparative Genomics and In Silico Assessment of Genes within the Genus Geobacillus
Najar, I. N.; Sharma, P.; Das, R.; Mondal, K.; Singh, A. K.; Radha, A.; Sharma, V.; Sharma, S.; Thakur, N.; Gandhi, S. G.; Kumar, V.
10.1101/2024.05.15.594408 — microbiology — Posted on 2024-05-16
2203 Expanding the cultivable human archaeome: Methanobrevibacter intestini sp. nov. and strain Methanobrevibacter smithii GRAZ-2 from human feces
Weinberger, V.; Mohammadzadeh, R.; Blohs, M.; Kalt, K.; Mahnert, A.; Moser, S.; Cecovini, M.; Mertelj, P.; Zurabishvili, T.; Wolf, J.; Shinde, T.; Madl, T.; Habisch, H.; Kolb, D.; Pernitsch, D.; Hingerl, K.; Metcalf, W.; Moissl-Eichinger, C.
10.1101/2024.05.15.594450 — microbiology — Posted on 2024-05-16
2204 Using machine learning to dissect host kinases required for Leishmania internalization and development
Wei, L.; Barrie, U.; Aloisio, G. M.; Khuong, F. T. H.; Arang, N.; Datta, A.; Kaushansky, A.; Wetzel, D. M.
10.1101/2024.05.16.593986 — microbiology — Posted on 2024-05-16
2205 Cell invasive amyloid assemblies from SARS-CoV-2 peptides can form multiple polymorphs with varying neurotoxicity
Sanislav, O.; Tetaj, R.; Ratcliffe, J.; Phillips, W.; Klein, A.; Sethi, A.; Zhou, J.; Mezzenga, R.; Saxer, S.; Charnley, M.; Annesley, S. J.; Reynolds, N.
10.1101/2024.05.16.594465 — biophysics — Posted on 2024-05-16
2209 Radiation-Induced Cellular Plasticity: A Strategy for Combatting Glioblastoma
He, L.; Azizad, D.; Bhat, K.; Ioannidis, A.; Hoffman, C. J.; Arambula, E.; Bhaduri, A.; Kornblum, H. I.; Pajonk, F.
10.1101/2024.05.13.593985 — cancer biology — Posted on 2024-05-16
2213 EZ-SPOTs: A simple and robust high-throughput liquid handling platform
Albo, J.; Tan, S.; Denis, J. D.; Franklin-Guild, R.; Shiri, S.; Sandoz, K. M.; Cira, N. J.
10.1101/2024.05.13.594031 — bioengineering — Posted on 2024-05-16
2215 Disentangling cell-intrinsic and extrinsic factors underlying gene expression evolution
Starr, A. L.; Nishimura, T.; Igarashi, K. J.; Funamoto, C.; Nakauchi, H.; Fraser, H.
10.1101/2024.05.06.592777 — evolutionary biology — Posted on 2024-05-16
2216 Harnessing defective interfering particles and lipid nanoparticles for effective delivery of an anti-dengue virus RNA therapy
Lin, M.-H.; Maniam, P.; Li, D.; Tang, B.; Bishop, C.; Suhrbier, A.; Wales-Earl, L.; Tayyar, Y.; McMillan, N. A. J.; Li, L.; Harrich, D.
10.1101/2024.04.23.590664 — microbiology — Posted on 2024-05-16
2217 Impact of microchannel width on axons for brain-on-chip applications
Vulic, K.; Amos, G.; Ruff, T.; Kasm, R.; Ihle, S. J.; Kuchler, J.; Voros, J.; Weaver, S.
10.1101/2024.05.16.594497 — neuroscience — Posted on 2024-05-16
2221 Effects of Concussion on the Relative Contributions of Sensorimotor Memories during Adaptation to Unpredictable Spring-Like Loads
Lantagne, D.; Mrotek, L. A.; Ahamed, S. I.; Beardsley, S. A.; Grove, A. J.; Leigh, D. H.; Smith, C. S.; Thomas, D. G.; Scheidt, R. A.
10.1101/2024.05.16.594491 — neuroscience — Posted on 2024-05-16
2222 A Demographic-Conditioned Variational Autoencoder for fMRI Distribution Sampling and Removal of Confounds
Orlichenko, A.; Qu, G.; Zhou, Z.; Liu, A.; Deng, H.-W.; Ding, Z.; Stephen, J.; Wilson, T.; Calhoun, V.; Wang, Y.-P.
10.1101/2024.05.16.594528 — neuroscience — Posted on 2024-05-16
2227 ninjaCap: A fully customizable and 3D printable headgear for fNIRS and EEG brain imaging
von Luhmann, A.; Kura, S.; O'Brien, J.; Zimmermann, B.; Duwadi, S.; Rogers, D.; Anderson, J. E.; Farzam, P.; Snow, C.; Chen, A.; Yucel, M. A.; Perkins, L. N.; Boas, D. A.
10.1101/2024.05.14.594159 — neuroscience — Posted on 2024-05-16
2229 The Endoplasmic Reticulum as an Active Liquid Network
Scott, Z. C.; Steen, S. B.; Huber, G.; Westrate, L. M.; Koslover, E. F.
10.1101/2024.05.15.594381 — biophysics — Posted on 2024-05-16
2233 Stress-induced brain extracellular vesicles ameliorate anxiety behaviour.
Mizohata, Y.; Yoshioka, Y.; Koga, M.; Toda, H.; Ohta, H.; Kobayashi, Y.; Ochiya, T.; Morimoto, Y.
10.1101/2024.05.16.594479 — animal behavior and cognition — Posted on 2024-05-16
2236 Analysis of developmental gene expression using smFISH and in silico staging of C. elegans embryos
Breimann, L.; Bahry, E.; Zouinkhi, M.; Kolyvanov, K.; Street, L. A.; Preibisch, S.; Ercan, S.
10.1101/2024.05.15.594414 — developmental biology — Posted on 2024-05-16
2237 Alternative splicing across the C. elegans nervous system
Weinreb, A.; Varol, E.; Barrett, A.; McWhirter, R. M.; Taylor, S. R.; Courtney, I.; Basavaraju, M.; Poff, A.; Tipps, J. A.; Collings, B.; The CeNGEN Consortium, ; Krishnaswamy, S.; Miller, D. M.; Hammarlund, M.
10.1101/2024.05.16.594567 — neuroscience — Posted on 2024-05-16
2238 A neuroimaging dataset during sequential color qualia similarity judgments with and without reports
Hirao, T.; Miyamae, M.; Matsuyoshi, D.; Inoue, R.; Takado, Y.; Obata, T.; Higuchi, M.; Tsuchiya, N.; Yamada, M.
10.1101/2024.05.16.594267 — neuroscience — Posted on 2024-05-16
2243 Balancing postural control and motor inhibition during gait initiation
Fiori, L.; Ramawat, S.; Marc, I. B.; Giuffrida, V.; Ranavolo, A.; Draicchio, F.; Pani, P.; Ferraina, S.; Brunamonti, E.
10.1101/2024.05.16.594550 — neuroscience — Posted on 2024-05-16
2244 DeepVID v2: Self-Supervised Denoising with Decoupled Spatiotemporal Enhancement for Low-Photon Voltage Imaging
Liu, C.; Lu, J.; Wu, Y.; Ye, X.; Ahrens, A. M.; Platisa, J.; Pieribone, V. A.; Chen, J. L.; Tian, L.
10.1101/2024.05.16.594448 — neuroscience — Posted on 2024-05-16
2245 Preclinical evaluation of the novel CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease
Zajicek, F.; Verhaeghe, J.; de Lombaerde, S.; Van Eetveldt, A.; Miranda, A.; Munoz-Sanjuan, I.; Dominguez, C.; Khetarpal, V.; Bard, J.; Liu, L.; Staelens, S.; Bertoglio, D.
10.1101/2024.05.16.594492 — neuroscience — Posted on 2024-05-16
2246 Identification and Pharmacological Targeting of Treatment-Resistant, Stem-like Breast Cancer Cells for Combination Therapy
Worley, J.; Noh, H.; You, D.; Turunen, M.; Ding, H.; Paull, E. O.; Griffen, A.; Grunn, A.; Zhang, M.; Guillan, K.; Bush, E.; Brosius, S.; Hibshoosh, H.; Mundi, P. S.; Sims, P.; Dalerba, P.; Dela Cruz, F. S.; Kung, A. L.; Califano, A.
10.1101/2023.11.08.562798 — systems biology — Posted on 2024-05-16
2251 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Naik, A.; Chang, A. N.; Miller, R. T.
10.1101/2024.02.26.582201 — cell biology — Posted on 2024-05-16
2256 Impaired sleep-dependent memory consolidation predicted by reduced sleep spindles in Rolandic epilepsy
Kwon, H.; Chinappen, D. M.; Kinard, E. A.; Goodman, S. K.; Huang, J. F.; Berja, E. D.; Walsh, K. G.; Shi, W.; Manoach, D. S.; Kramer, M. A.; Chu, C. J.
10.1101/2024.05.16.594515 — neuroscience — Posted on 2024-05-16
2260 Transposable Elements Shape Stemness in Normal and Leukemic Hematopoiesis
Grillo, G.; Nadorp, B.; Qamra, A.; Mitchell, A.; Arlidge, C.; Nand, A.; Takayama, N.; Murison, A.; Tonekaboni, S. A. M.; Arruda, A.; Wang, J.; Minden, M.; Deniz, O.; Boutzen, H.; Dick, J.; Lupien, M.
10.1101/2021.02.16.431334 — cancer biology — Posted on 2024-05-16
2261 Enhancer plasticity in endometrial tumorigenesis demarcates non-coding somatic mutations and 3D-genome alterations boosting the oncogenic driver ESR1
Gregoricchio, S.; Kojic, A.; Hoogstraat, M.; Schuurman, K.; Stelloo, S.; Severson, T. M.; O'Mara, T. A.; Droog, M.; Singh, A. A.; Glubb, D. M.; Wessels, L. F. A.; Vermeulen, M.; van Leeuwen, F.; Zwart, W.
10.1101/2023.07.25.550368 — cancer biology — Posted on 2024-05-16
2262 Likelihood-based interactive local docking into cryo-EM maps in ChimeraX
Read, R. J.; Pettersen, E. F.; McCoy, A. J.; Croll, T. I.; Terwilliger, T. C.; Poon, B. K.; Meng, E. C.; Liebschner, D.; Adams, P. D.
10.1101/2024.05.16.594509 — biophysics — Posted on 2024-05-16
2266 Genome-wide profiling of highly similar paralogous genes using HiFi sequencing
Chen, X.; Baker, D.; Dolzhenko, E.; Devaney, J. M.; Noya, J.; Berlyoung, A. S.; Brandon, R.; Hruska, K. S.; Lochovsky, L.; Kruszka, P.; Newman, S.; Farrow, E.; Thiffault, I.; Pastinen, T.; Kasperaviciute, D.; Gilissen, C.; Vissers, L.; Hoischen, A.; Berger, S.; Vilain, E.; Delot, E.; UCI Genomics Research to Elucidate the Genetics of Rare Diseases (UCI GREGoR) Consortium, ; Eberle, M. A.
10.1101/2024.04.19.590294 — genomics — Posted on 2024-05-16
2269 Binding of cortical functional modules by synchronous high frequency oscillations
Garrett, J. C.; Verzhbinsky, I. A.; Kaestner, E.; Carlson, C.; Doyle, W. K.; Devinsky, O.; Thesen, T.; Halgren, E.
10.1101/2023.05.20.541597 — neuroscience — Posted on 2024-05-16
2270 The wake- and sleep-modulating neurons of the lateral hypothalamic area demonstrate a differential pattern of degeneration in Alzheimers disease
Satpati, A.; Pereira, F. L.; Soloviev, A. V.; Mladinov, M.; Larsen, E.; Hua, S. L.; Tu, C.-L.; Leite, R. E. P.; Suemoto, C. K.; Rodriguez, R. D.; Paes, V. R.; Walsh, C.; Spina, S.; Seeley, W. W.; Pasqualucci, C. A.; Filho, W. J.; Chang, W.; Neylan, T. C.; Grinberg, L. T.
10.1101/2024.03.06.583765 — neuroscience — Posted on 2024-05-16
2274 Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
Kamat, P.; Macaluso, N.; Min, C.; Li, Y.; Agrawal, A.; Winston, A.; Pan, L.; Starich, B.; Stewert, T.; Wu, P.-H.; Fan, J.; Walston, J.; Phillip, J. M.
10.1101/2024.05.10.593637 — bioengineering — Posted on 2024-05-16
2276 A UHPLC MS/MS method for determination of N-acylethanolamines in cerebrospinal fluid
Ismoilova, V.; Wretlind, A.; Hooshmand, K.; Simonsen, A. H.; Hasselbalch, S. G.; Legido-Quigley, C.
10.1101/2023.11.20.567867 — biochemistry — Posted on 2024-05-16
2279 Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting
Greco, F. A.; Kraemer, A.; Wahl, L.; Elson, L.; Ehret, T.; Gerninghaus, J.; Moeckel, J.; Mueller, S.; Hanke, T.; Knapp, S.
10.1101/2024.05.16.594086 — biochemistry — Posted on 2024-05-16
2281 Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity
Sayeed, K.; Parameswaran, S.; Beucler, M. J.; Edsall, L. E.; VonHandorf, A.; Crowther, A.; Donmez, O. A.; Hass, M. R.; Richards, S.; Forney, C. R.; Wright, J.; Leong, M. M.; Murray-Nerger, L. A.; Gewurz, B. E.; Kaufman, K. M.; Harley, J. B.; Zhao, B.; Miller, W. E.; Kottyan, L. C.; Weirauch, M. T.
10.1101/2024.04.12.588762 — genomics — Posted on 2024-05-16
2282 Structural insights into transcription regulation of the global virulence factor PhoP from Mycobacterium tuberculosis
Shi, J.; Song, Q.; Feng, Z.; Wen, A.; Liu, T.; Xu, L.; Ye, Z.; Xu, S.; Gao, F.; Xiao, L.; Zhu, J.; Das, K.; Zhao, G.-P.; Feng, Y.; Lin, W.
10.1101/2024.05.16.594476 — microbiology — Posted on 2024-05-16
2283 Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
Gao, Y.; Dong, Q.; Arachchilage, K. H.; Risgaard, R.; Sheng, J.; Syed, M.; Schmidt, D. K.; Jin, T.; Liu, S.; Knaack, S. A.; Doherty, D.; Glass, I.; Levine, J. E.; Wang, D.; Chang, Q.; Zhao, X.; Sousa, A. M.
10.1101/2023.06.02.543460 — neuroscience — Posted on 2024-05-16
2287 RatXcan: A framework for cross-species integration of genome-wide association and gene expression data
Santhanam, N.; Sanchez-Roige, S.; Mi, S.; Liang, Y.; Chitre, A.; Munro, D.; Chen, D.; Cheng, R.; Nyasimi, F.; Gao, J.; George, A. M.; Gileta, A. F.; Holl, K.; Hughson, A.; King, C. P.; Lamparelli, A. C.; Martin, C. D.; Martinez, A. G.; St. Pierre, C. L.; Tripi, J.; Wang, T.; Chen, H.; Flagel, S.; Ishiwari, K.; Meyer, P.; Polesskaya, O.; Saba, L.; Woods, L. S.; Palmer, A. A.; Im, H. K.
10.1101/2022.06.03.494719 — genomics — Posted on 2024-05-16
2290 Resolving atomic-level dynamics and interactions of high-molecular weight hyaluronic acid by multidimensional solid-state NMR
Rampratap, P.; Lasorsa, A.; Arunachalam, A.; Kamperman, M.; Walvoort, M. T. C.; van der Wel, P. C. A.
10.1101/2024.02.29.582163 — biophysics — Posted on 2024-05-16
2293 The main duct of von Ebner's glands is a source of Sox10+ taste bud progenitors and susceptible to pathogen infections
Kastriti, M. E.; Ishan, M.; Choudhary, S. K.; KRAMER, N. E.; Rashid, M. M.; Do, H. G. T.; Wang, Z.; Xu, T.; Schwabe, R. F.; Ye, K.; Adameyko, I.; Liu, H.-X.
10.1101/2024.05.14.594215 — cell biology — Posted on 2024-05-16
2297 UNC-10/SYD-2 links kinesin-3 to RAB-3-containing vesicles in the absence of the motor's PH domain
Bayansan, O.; Bhan, P.; Chang, C.-Y.; Barmaver, S. N.; Shen, C.-P.; Wagner, O.
10.1101/723247 — cell biology — Posted on 2024-05-16
2299 Inducing aggresome and insoluble tau aggregation using an optogenetic tool
Sakuragi, S.; Uchida, T.; Kato, N.; Zhao, B.; Hattori, A.; Sakata, Y.; Soeda, Y.; Takashima, A.; Yoshimura, H.; Matsumoto, G.; Bannai, H.
10.1101/2024.05.07.592868 — biophysics — Posted on 2024-05-16
2302 Accelerated growth increases the somatic epimutation rate in trees
Zhou, M.; Schmied, G.; Bradatsch, M.; Resente, G. A.; Hazarika, R. R.; Kakoulidou, I.; Costa, M.; Serra, M.; Uhl, E.; Schmitz, R. J.; Hilmers, T.; Caicoya, A. T.; Crivellaro, A.; Pretzsch, H.; Johannes, F.
10.1101/2024.05.07.592680 — genomics — Posted on 2024-05-16
2303 Intensifying marine heatwaves and limited protection threaten global kelp forests
Arafeh-Dalmau, N.; Villasenor-Derbez, J. C.; Schoeman, D. S.; Soto, A. M.; Bell, T. W.; Butler, C. L.; Costa, M.; Dunga, L. V.; Houskeeper, H. F.; Lagger, C.; Pantano, C.; Lainez del Pozo, D.; Sink, K. J.; Micheli, F.; Cavanaugh, K. C.
10.1101/2024.05.13.594016 — ecology — Posted on 2024-05-16
2305 Novel Anti-virulence Compounds Disrupt Exotoxin Expression in MRSA
Balogh, H.; Anthony, A.; Stempel, R.; Vossen, L.; Federico, V. A.; Valenzano, G. Z.; Blackledge, M. S.; Miller, H. B.
10.1101/2024.05.15.594412 — microbiology — Posted on 2024-05-16
2306 Adipocyte microRNA-802 promotes adipose tissue inflammation and insulin resistance by modulating macrophages in obesity
yang, y.; huang, b.; qin, y.; wang, d.; jin, y.; su, l.; pan, Y.; zhang, y.; shen, y.; hu, w.; Cao, Z.; Jin, L.; Zhang, F.
10.1101/2024.05.13.593999 — immunology — Posted on 2024-05-16
2307 Deep proteomic analysis of human microglia and model systems reveal fundamental biological differences of in vitro and ex vivo cells
Lloyd, A. F.; Martinez-Muriana, A.; Davis, E.; Daniels, M. J.; Hou, P.; Mancuso, R.; Brenes-Murillo, A. J.; Geric, I.; Snellinx, A.; Craessaerts, K.; Theys, T.; Fiers, M.; De Strooper, B.; Howden, A. J.
10.1101/2022.07.07.498804 — neuroscience — Posted on 2024-05-16
2308 Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer
Lancaster, N. M.; Sinitcyn, P.; Forny, P.; Peters-Clarke, T. M.; Fecher, C.; Smith, A. J.; Shishkova, E.; Arrey, T. N.; Pashkova, A.; Robinson, M. L.; Arp, N.; Fan, J.; Hansen, J.; Galmozzi, A.; Serrano, L. R.; Rojas, J.; Gasch, A. P.; Westphall, M. S.; Stewart, H.; Hock, C.; Damoc, E.; Pagliarini, D. J.; Zabrouskov, V.; Coon, J. J.
10.1101/2023.11.21.568149 — systems biology — Posted on 2024-05-16
2311 A sexually dimorphic hepatic cycle of periportal VLDL generation and subsequent pericentral VLDLR-mediated lipoprotein re-uptake
Martini, T.; Gobet, C.; Salati, A.; Blanc, J.; Mookhoek, A.; Reinehr, M.; Knott, G.; Sordet-Dessimoz, J.; Naef, F.
10.1101/2023.10.07.561324 — physiology — Posted on 2024-05-16
2314 Age-related changes in 'cortical' 1/f dynamics are linked to cardiac activity
Schmidt, F.; Danboeck, S. K.; Trinka, E.; Klein, D. P.; Demarchi, G.; Weisz, N.
10.1101/2022.11.07.515423 — neuroscience — Posted on 2024-05-16
2315 CTNND2 regulation by the SRGAP2 protein family links human evolution to synaptic neoteny
Assendorp, N. M.; Fossati, M.; Libe-Philippot, B.; Christopoulou, E.; Depp, M.; Rapone, R.; Dingli, F.; Loew, D.; Vanderhaeghen, P.; Charrier, C.
10.1101/2022.09.13.507776 — neuroscience — Posted on 2024-05-16
2316 An integrated picture of the structural pathways controlling the heart performance
Morotti, I.; Caremani, M.; Marcello, M.; Pertici, I.; Bianco, P.; Theyencheri, N.; Piazzesi, G.; Reconditi, M.; Lombardi, V.; Linari, M.
10.1101/2024.05.11.593706 — physiology — Posted on 2024-05-16
2317 Motion Blur Microscopy
Goreke, U.; Gonzales, A.; Shipley, B.; Tincher, M.; Sharma, O.; Wulftange, W.; Man, Y.; An, R.; Hinczewski, M.; Gurkan, U. A.
10.1101/2023.10.08.561435 — biophysics — Posted on 2024-05-16
2318 Multi-Scale Protein Language Model for Unified Molecular Modeling
Zheng, K.; Long, S.; Lu, T.; Yang, J.; Dai, X.; Zhang, M.; Nie, Z.; Ma, W.-Y.; Zhou, H.
10.1101/2024.03.04.583284 — bioinformatics — Posted on 2024-05-16
2323 Targeting circadian transcriptional programs in triple negative breast cancer through a cis-regulatory mechanism
Pan, Y.; Chiu, T.-P.; Zhou, L.; Chan, P.; Kuo, T. T.; Battaglin, F.; Soni, S.; Lenz, H.-J.; Jayachandran, P.; Li, J. J.; Mumenthaler, S.; Rohs, R.; Roussos Torres, E.; Kay, S. A.
10.1101/2024.04.26.590360 — cancer biology — Posted on 2024-05-15
2326 Gas tunnel engineering of prolyl hydroxylasereprograms hypoxia signaling in cells
Windsor, P.; Ouyang, H.; da Costa, J. A. G.; Damodaran, A. R.; Chen, Y.; Bhagi-Damodaran, A.
10.1101/2023.08.07.552357 — biochemistry — Posted on 2024-05-16
2328 Novel cell states arise in embryonic cells devoid of key reprogramming factors
Youlten, S. E.; Miao, L.; Hoppe, C.; Boswell, C. W.; Musaev, D.; Abdelmessih, M.; Krishnaswamy, S.; Tornini, V. A.; Giraldez, A. J.
10.1101/2024.05.13.593729 — developmental biology — Posted on 2024-05-15
2329 Haploidy-linked cell proliferation defects limit larval growth in Zebrafish
Yaguchi, K.; Saito, D.; Menon, T.; Matsura, A.; Hosono, M.; Mizutani, T.; Kotani, T.; Nair, S.; Uehara, R.
10.1101/2022.05.12.491746 — developmental biology — Posted on 2024-05-16
2330 Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors
Wang, F.; Holmes, M. J.; Hong, H. J.; Thaprawat, P.; Kannan, G.; Huynh, M.-H.; Schultz, T. L.; Licon, M. H.; Lourido, S.; Dong, W.; Brito Querido, J.; Sullivan, W. J.; O Leary, S. E.; Carruthers, V. B.
10.1101/2023.11.03.565545 — microbiology — Posted on 2024-05-15
2331 Sac1 links phosphoinositide turnover to cryptococcal virulence
Gaylord, E. A.; Choy, H. L.; Chen, G.; Briner, S. L.; Doering, T. L.
10.1101/2024.01.18.576303 — microbiology — Posted on 2024-05-15
2332 POSTERIOR-SUPERIOR INSULA REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION REDUCES EXPERIMENTAL TONIC PAIN AND PAIN-RELATED CORTICAL INHIBITION IN HUMANS
Chowdhury, N. S.; Millard, S. K.; De Martino, E.; Larsen, D. B.; Seminowicz, D. A.; Schabrun, S. M.; Andrade, D. C. d.; Graven-Nielsen, T.
10.1101/2024.05.14.594260 — neuroscience — Posted on 2024-05-15
2333 Cortico-amygdala synaptic structural abnormalities produced by templated aggregation of α-synuclein
Gcwensa, N. Z.; Russell, D. L.; Long, K. Y.; Brzozowski, C. F.; Liu, X.; Gamble, K. L.; Cowell, R. M.; Volpicelli-Daley, L.
10.1101/2024.05.15.594419 — neuroscience — Posted on 2024-05-15
2334 A left-lateralized dorsolateral prefrontal network for naming
Yu, L.; Dugan, P.; Doyle, W.; Devinsky, O.; Friedman, D.; Flinker, A.
10.1101/2024.05.15.594403 — neuroscience — Posted on 2024-05-16
2335 Developmental and adult striatal patterning of nociceptin ligand marks striosomal population with direct dopamine projections
Hueske, E.; Stine, C.; Yoshida, T.; Crittenden, J. R.; Gupta, A.; Johnson, J. C.; Achanta, A. S.; Loftus, J.; Mahar, A.; Hu, D.; Azocar, J.; Gray, R. J.; Bruchas, M. R.; Graybiel, A. M.
10.1101/2024.05.15.594426 — neuroscience — Posted on 2024-05-16
2339 Enhancing affinity of neutralizing SARS-CoV-2 nanobody through facile structure-guided mutations in CDRs
Singh, V.; Bhutkar, M.; Choudhary, S.; Nehul, S.; Kumar, R.; Singla, J.; Kumar, P.; Tomar, S.
10.1101/2024.05.13.593833 — bioengineering — Posted on 2024-05-15
2340 Dual-Action Kinase Inhibitors Control p38α MAP Kinase Threonine Dephosphorylation
Stadnicki, E.; Ludewig, H.; Kumar, R. P.; Wang, X.; Qiao, Y.; Kern, D.; Bradshaw, N.
10.1101/2024.05.15.594272 — biochemistry — Posted on 2024-05-15
2341 An AI-Driven Framework for Discovery of BACE1 Inhibitors for Alzheimer's Disease
Xie, E.; Hasegawa, K.; Kementzidis, G.; Papadopoulos, E.; Aktas, B. H.; Deng, Y.
10.1101/2024.05.15.594361 — biochemistry — Posted on 2024-05-15
2344 Clostridium ablates tumors by degrading collagen mesh andinducing ferroptosis
Yang, F.; Lu, M.; Chen, H.; Wang, X.; Zhang, M.; Cao, Z.; Pang, Y.; Liu, J.
10.1101/2024.05.15.594430 — microbiology — Posted on 2024-05-15
2345 Novel Anti-virulence Compounds Disrupt Exotoxin Expression in MRSA
Balogh, H.; Stempel, R.; Vossen, L.; Federico, V. A.; Valenzano, G. Z.; Blackledge, M. S.; Miller, H. B.
10.1101/2024.05.15.594412 — microbiology — Posted on 2024-05-15
2348 IL-4 Licenses B Cell Activation Through Cholesterol Synthesis
Steach, H. R.; York, A. G.; Skadow, M. H.; Chen, S.; Zhao, J.; Williams, K. J.; Zhou, Q.; Hsieh, W.-Y.; Brewer, J. R.; Qu, R.; Shyer, J. A.; Harman, C.; Sefik, E.; Mowell, W. K.; Bailis, W.; Cui, C.; Kluger, Y.; Bensinger, S. J.; Craft, J.; Flavell, R.
10.1101/2024.05.13.593964 — immunology — Posted on 2024-05-15
2350 Decoding glycosylation potential from protein structure across human glycoproteins with a multi-view recurrent neural network
Kellman, B.; Mariethoz, J.; Zhang, Y.; Shaul, S.; Jeffris, M.; Sandoval, D.; Jeffris, M.; Armingol, E.; Bao, B.; Lisacek, F.; Bojar, D.; Lewis, N.
10.1101/2024.05.15.594334 — bioinformatics — Posted on 2024-05-15
2351 PathoGD: an integrative genomics approach for CRISPR-based target design of rapid pathogen diagnostics
Low, S. J.; O'Neill, M.; Kerry, W. J.; Wild, N.; Krysiak, M.; Nong, Y.; Azzato, F.; Hor, E.; Williams, L.; Taiaroa, G.; Steinig, E.; Pasricha, S.; Williamson, D.
10.1101/2024.05.14.593882 — bioinformatics — Posted on 2024-05-15
2352 Cramming Protein Language Model Training in 24 GPU Hours
Frey, N. C.; Joren, T.; Ismail, A.; Goodman, A.; Bonneau, R.; Cho, K.; Gligorijevic, V.
10.1101/2024.05.14.594108 — bioengineering — Posted on 2024-05-15
2353 Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights
Saran, A.; Kim, H.-M.; Manning, I.; Hancock, M. A.; Schmitz, C.; Madej, M.; Potempa, J.; Sola, M.; Trempe, J.-F.; Zhu, Y.; Davey, M.; Zeytuni, N.
10.1101/2024.05.15.594396 — biochemistry — Posted on 2024-05-15
2355 AARS Online: a collaborative database on the structure, function, and evolution of the aminoacyl-tRNA synthetases
Douglas, J.; Cui, H.; Perona, J. J.; Rodriguez, O. V.; Tyynismaa, H.; Alvarez-Carreno, C.; Ling, J.; Ribas-de-Pouplana, L.; Yang, X.-L.; Ibba, M.; Becker, H.; Fischer, F.; Sissler, M.; Carter, C. W.; Wills, P.
10.1101/2024.05.15.594223 — biochemistry — Posted on 2024-05-15
2356 Trifunctional fatty acid derivatives demonstrate the impact of diazirine placement
Farley, S. E.; Hashimoto, R.; Evangelista, J.; Stein, F.; Haberkant, P.; Kikuchi, K.; Tafesse, F.; Schultz, C.
10.1101/2024.05.15.594383 — biochemistry — Posted on 2024-05-15
2359 Bioarchaeological Perspectives on Late Antiquity in Dalmatia: Paleogenetic, Dietary, and Population Studies of the Hvar Radosevic burial site
Zagorc, B.; Blanz, M.; Sawyer, S.; Gelabert, P.; Oberreiter, V.; Cheronet, O.; Chen, H. S.; Caric, M.; Viskovic, E.; Olalde, I.; Ivanova-Bieg, M.; Novak, M.; Reich, D. E.; Pinhasi, R.
10.1101/2024.05.14.594056 — genomics — Posted on 2024-05-15
2360 Protein structure, a genetic encoding for glycosylation
Kellman, B.; Sandoval, D.; Zaytseva, O.; Brock, K.; Baboo, S.; Nachmanson, D.; Irvine, E.; Armingol, E.; Mih, N.; Zhang, Y.; Jeffris, M.; Bartels, P.; Nguyen, T.; Tam, A.; Gasman, S.; Ilan, S.; Shamie, I.; Diedrich, J.; Wang, X.; van Woudenbergh, E.; Altman, M.; Aylward, A.; Bao, B.; Castro, A.; Sorrentino, J.; Chiang, A.; Campbell, M.; Bartsch, Y.; Aguilar-Calvo, P.; Sigurdson, C.; Alter, G.; Lauc, G.; Yates, Y.; Marks, D.; Lisacek, F.; Lewis, N.
10.1101/2024.05.15.594261 — genetics — Posted on 2024-05-15
2361 The 18S rRNA Methyltransferase DIMT-1 Regulates Lifespan in the Germline Later in Life
Rothi, M. H.; Sarkar, G. C.; Al Haddad, J.; Mitchell, W.; Ying, K.; Pohl, N.; Sotomayor-Mena, R. G.; Natale, J.; Dellacona, S.; Gladyshev, V. N.; Greer, E. L.
10.1101/2024.05.14.594211 — genetics — Posted on 2024-05-15
2363 Sodium/Potassium ATPase Alpha 1 Subunit Fine-tunes Platelet GPCR Signaling Function and is Essential for Thrombosis
Li, O. Q.; Yue, H.; DeHart, A.; Roytenberg, R.; Aguilar, R.; Olanipekun, O.; Bai, F.; Liu, J.; Fedorova, O.; Kennedy, D.; Thompson, E.; Pierre, S.; Li, W.
10.1101/2024.05.13.593923 — cell biology — Posted on 2024-05-15
2364 Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts
Rudman-Melnick, V.; Vanhoutte, D.; Jenkins, K.; Sargent, M.; Adam, M.; Ma, Q.; Perl, A.-K. T.; Miethke, A.; Burg, A.; Shi, T.; Hildeman, D.; Woodle, E. S.; Kofron, J. M.; DEVARAJAN, P.
10.1101/2024.05.15.594404 — molecular biology — Posted on 2024-05-15
2366 Epigenetic control of CD8+ T cell tissue homing and tissue resident memory T cell precursors by the histone methyltransferase SUV39H1
Suarez, G.; Heurtebise-Chretien, S.; Bonte, P.-E.; Beuchet, H.; Fuentealba, J.; Goudot, C.; Lantz, O.; Amigorena, S.
10.1101/2024.05.13.593994 — immunology — Posted on 2024-05-15
2368 Efficient Genetic Code Expansion Without Host Genome Modifications
Costello, A.; Peterson, A.; Lanster, D.; Li, Z.; Carver, G.; Badran, A.
10.1101/2024.05.15.594368 — synthetic biology — Posted on 2024-05-15
2373 Precision fMRI reveals that the language network exhibits adult-like left-hemispheric lateralization by 4 years of age
Ozernov-Palchik, O.; O'Brien, A. M.; Lee, E. J.; Richardson, H.; Romeo, R.; Lipkin, B.; Small, H.; Capella, J.; Nieto-Castanon, A.; Saxe, R.; Gabrieli, J. D. E.; Fedorenko, E.
10.1101/2024.05.15.594172 — neuroscience — Posted on 2024-05-15
2375 Pharmacological Ascorbate Induces Transient Hypoxia Sensitizing Pancreatic Ductal Adenocarcinoma to a Hypoxia Activated Prodrug
Kishimoto, S.; Crooks, D. R.; Yasunori, O.; Kota, Y.; Yamamoto, K.; Linehan, M.; Levine, M.; Krishna, M. C.; Brender, J. R.
10.1101/2024.05.13.593896 — cancer biology — Posted on 2024-05-15
2377 CellAgent: An LLM-driven Multi-Agent Framework for Automated Single-cell Data Analysis
Yihang, X.; Jinyi, L.; Yan, Z.; Xiaohan, X.; Mingzhi, L.; Jianye, H.; Ruitao, W.; Fei, N.; Yuxiao, L.; Jintian, L.; Shaoqing, J.; Peng, J.
10.1101/2024.05.13.593861 — bioinformatics — Posted on 2024-05-15
2384 Efficient Federated Learning for distributed NeuroImaging Data
Thapaliya, B.; Ohib, R.; Geenjaar, E. P. T.; Liu, J.; Calhoun, V.; Plis, S.
10.1101/2024.05.14.594167 — neuroscience — Posted on 2024-05-15
2385 Distinct representation of navigational action affordances in human behavior, brains and deep neural networks
Bartnik, C. G.; Sartzetaki, C.; Puigseslloses Sanchez, A.; Molenkamp, E.; Bommer, S.; Vuksic, N.; Groen, I. I. A.
10.1101/2024.05.15.594298 — neuroscience — Posted on 2024-05-15
2387 Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease
Sodders, M. J.; Avila-Pacheco, J.; Okorie, E. C.; Shen, M.; Kumari, N.; Marathi, A.; Lakhani, M.; Bullock, K.; Pierce, K.; Dennis, C.; Jeanfavre, S.; Sarkar, S.; Scherzer, C. R.; Clish, C.; Olsen, A. L.
10.1101/2024.05.15.594309 — neuroscience — Posted on 2024-05-15
2390 A selective GSK3β inhibitor, tideglusib, decreases intermittent access and binge ethanol self-administration in C57BL/6J mice
Gottlieb, S.; van der Vaart, A.; Hassan, A.; Bledsoe, D.; Morgan, A.; O'Rourke, B.; Rogers, W. D.; Wolstenholme, J. T.; Miles, M. F.
10.1101/2024.05.13.593949 — pharmacology and toxicology — Posted on 2024-05-15
2391 Phylogenetic-based methods for fine-scale classification of PRRSV-2 ORF5 sequences: a comparison of their robustness and reproducibility
VanderWaal, K.; Pamornchainvakul, N.; Kikuti, M.; Linhares, D.; Trevisan, G.; Zhang, J.; Anderson, T. K.; Zeller, M.; Rossow, S.; Holtkamp, D. J.; Makau, D. N.; Corzo, C. A.; Paploski, I. A. D.
10.1101/2024.05.13.593920 — bioinformatics — Posted on 2024-05-15
2394 Loss-of-function of ALDH3B2 transdifferentiates human pancreatic duct cells into beta-like cells
Li, J.; Bode, K.; Lee, Y.-c.; Morrow, N.; Ma, A.; Wei, S.; da Silva Pereira, J.; Stewart, T.; Lee-Papastavros, A.; Hollister-Lock, J.; Sullivan, B.; Bonner-Weir, S.; Yi, P.
10.1101/2024.05.13.593941 — genetics — Posted on 2024-05-15
2395 Genetic and environmental contributions to eigengene expression
Gillespie, N. A.; Bell, T. R.; Hearn, G. C.; Hess, J. L.; Tsuang, M. T.; Lyons, M. J.; Franz, C. E.; Kremen, W. S.; Glatt, S. J.
10.1101/2024.05.13.593914 — genetics — Posted on 2024-05-15
2397 Mucin-2 ER-to-Golgi transport mechanism identifies source of ER stress in inflammatory bowel disease
Morsink, M. A. J.; Koch, L. S.; Hu, S.; Weersma, R. K.; van Goor, H.; Bourgonje, A. R.; Broersen, K.
10.1101/2024.05.13.593851 — cell biology — Posted on 2024-05-15
2398 A Postdoctoral Training Program in Bioimage Analysis
Cimini, B. A.; Tromans-Coia, C.; Stirling, D. R.; Sivagurunathan, S.; Senft, R. A.; Ryder, P. V.; Miglietta, E.; Llanos, P.; Jamali, N.; Diaz-Rohrer, B.; Dasgupta, S.; Costa Cruz, M.; Weisbart, E.; Carpenter, A. E.
10.1101/2024.05.13.593910 — cell biology — Posted on 2024-05-15
2400 Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells
Haberman, N.; Cheung, R.; Pizza, G.; Cvetesic, N.; Nagy, D.; Maude, H.; Blazquez, L.; Lenhard, B.; Cebola, I.; Rutter, G. A.; Martinez-Sanchez, A.
10.1101/2024.05.13.593867 — cell biology — Posted on 2024-05-15
2403 Activation of the proteasome 20S Core particle prevents neuronal death induced by oxygen- and glucose deprivation in cultured neurons
L. Salazar, I.; Curcio, M.; Mele, M.; Vetrone, R.; Frisari, S.; O. Costa, R.; V. Caldeira, M.; J Trader, D.; B.Duarte, C.
10.1101/2024.05.15.594129 — neuroscience — Posted on 2024-05-15
2404 Excitoprotective effects of conditional tau reduction in excitatory neurons and in adulthood
Voskobiynyk, Y.; Li, Z.; Cochran, J. N.; Davis, M. N.; Carullo, N. V.; Creed, R. B.; Buckingham, S. C.; Hall, A. M.; Wilson, S. M.; Roberson, E. D.
10.1101/2024.05.14.594246 — neuroscience — Posted on 2024-05-15
2408 POSTERIOR-SUPERIOR INSULA REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION REDUCES EXPERIMENTAL TONIC PAIN AND PAIN-RELATED CORTICAL INHIBITION IN HUMANS
Chowdhury, N. S.; Millard, S. K.; De Martino, E.; Larsen, D. B.; Seminowicz, D. A.; Schabrun, S. M.; Andrade, D. C. d.; Graven-Nielsen, T.
10.1101/2024.05.14.594260 — neuroscience — Posted on 2024-05-15
2412 Functional Magnetic Resonance Spectroscopy of Prolonged Motor Activation using Conventional and Spectral GLM Analyses
Morelli, M.; Dudzikowska, K.; Deelchand, D. K.; Quinn, A. J.; Mullins, P. G.; Apps, M. A. J.; Wilson, M.
10.1101/2024.05.15.594270 — neuroscience — Posted on 2024-05-15
2415 Test Retest Reliability of Meta Analytic Networks During Naturalistic Viewing
Kroell, J.-P.; Friedrich, P.; Li, X.; Nurislamova, Y.; Kraljevic, N.; Geiger, A.; Mans, J.; Waite, L.; Caspers, J.; Qian, X.; Chee, M. W.; Zhou, J. H.; Eickhoff, S.; Weis, S.
10.1101/2024.05.15.594266 — neuroscience — Posted on 2024-05-15
2417 MEA-seqX: High-resolution Profiling of Large-scale Electrophysiological and Transcriptional Network Dynamics
Emery, B. A.; Hu, X.; Kluetsch, D.; Khanzada, S.; Larsson, L.; Dumitru, I.; Frisen, J.; Lundeberg, J.; Kempermann, G.; Amin, H.
10.1101/2024.05.15.594367 — neuroscience — Posted on 2024-05-15
2418 Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes
Stedehouder, J.; Roberts, B. M.; Raina, S.; Bossi, S.; Liu, A. K. L.; Doig, N. M.; McGerty, K.; Magill, P. J.; Parkkinen, L.; Cragg, S. J.
10.1101/2024.05.15.594341 — neuroscience — Posted on 2024-05-15
2425 Brain-specific Gata4 downregulation in Greywick female mice models the metabolic subtype of polycystic ovary syndrome
Nawaito, S. A.; Esmael, M.; Souchkova, O.; Cardinal, T.; Bernas, G.; Bergeron, K.-F.; Gayda, F.; Bergeron, F.; Bouchard, M.-F.; Zhou, X.; Ongaro, L.; Bernard, D. J.; Short, J.; Wray, S.; Viger, R. S.; Mounier, C.; Pilon, N.
10.1101/2024.05.13.593880 — physiology — Posted on 2024-05-15
2427 Deep phenotyping of the prostate tumor microenvironment reveals molecular stratifiers of relapse and links inflammatory chemokine expression to aberrant metabolism
Krossa, S.; Andersen, M. K.; Midtbust, E.; Wess, M.; Kiviaho, A.; Sharma, A.; Viset, T.; Storkersen, O.; Giskeodegard, G. F.; Nykter, M.; Urbanucci, A.; Rye, M. B.; Tessem, M.-B.
10.1101/2024.05.13.593822 — cancer biology — Posted on 2024-05-15
2428 Microfluidic platform for microbial spore germination studies in multiple growth conditions
Bernier, L. S.; Estoppey, A.; Bindschedler, S.; Stan, G.-B. V.; Junier, P.; Stanley, C. E.
10.1101/2024.05.13.593863 — bioengineering — Posted on 2024-05-15
2429 Magnetically Steered Cell Therapy For Functional Restoration Of Intraocular Pressure Control In Open-Angle Glaucoma
Bahrani Fard, M. R.; Chan, J.; Read, A. T.; Li, G.; Cheng, L.; N Safa, B.; Siadat, S. M.; Jhunjhunwala, A.; Grossniklaus, H. E.; Emelianov, S. Y.; Stamer, W. D.; Kuehn, M. H.; Ethier, C. R.
10.1101/2024.05.13.593917 — bioengineering — Posted on 2024-05-15
2436 Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells
van Bentum, M.; Klinger, B.; Sieber, A.; Lehmann, N.; Haji, M.; Naghiloo, S.; Niquet, S.; Mertins, P.; Bluthgen, N.; Selbach, M.
10.1101/2024.05.13.593849 — systems biology — Posted on 2024-05-15
2437 Toxoplasma gondii infection accelerates the progression of hereditary spastic paraplegia
Alvin, J. R.; Ramirez-Flores, C. J.; Mendina, C. A.; Audhya, A.; Knoll, L. J.; Lettman, M. M.
10.1101/2024.05.15.594284 — microbiology — Posted on 2024-05-15
2439 Cathepsin X is a conserved cell death protein involved in algal response to environmental stress
Mizrachi, A.; Sadeh, M.; Ben-Dor, S.; Dym, O.; Ku, C.; Feldmesser, E.; Zarfin, A.; Brunson, J. K.; Allen, A. E.; Jinkerson, R. E.; Schatz, D.; Vardi, A.
10.1101/2024.05.15.594278 — microbiology — Posted on 2024-05-15
2441 Active Microtubule-Actin Crosstalk Mediated by a Nesprin-2G-Kinesin Complex
Sahabandu, N.; Okada, K.; Khan, A.; Elnatan, D.; Starr, D.; Ori-McKenney, K. M.; Luxton, G. G.; McKenney, R. J.
10.1101/2024.05.13.594030 — biophysics — Posted on 2024-05-15
2444 The nucleating agent crystallophore induces instant protein crystallization
Sauter, C.; Housset, D.; Orlans, J.; de Wijn, R.; Rollet, K.; Rose, S.; Basu, S.; Benas, P.; Perez, J.; de Sanctis, D.; Maury, O.; Girard, E.
10.1101/2024.05.13.593864 — biophysics — Posted on 2024-05-15
2447 An integrative characterisation of proline cis and trans conformers in a disordered peptide
Pettitt, A. J.; Shukla, V. K.; Figueiredo, A. M.; Newton, L. S.; McCarthy, S.; Tabor, A. B.; Heller, G. T.; Lorenz, C. D.; Hansen, D. F.
10.1101/2024.05.14.594077 — biophysics — Posted on 2024-05-15
2449 Beyond the Triple Helix: Exploration of the Hierarchical Assembly Space of Collagen-like Peptides
Yu, L. T.; Kreutzberger, M. A. B.; Hancu, M. C.; Bui, T. H.; Farsheed, A. C.; Egelman, E. H.; Hartgerink, J. D.
10.1101/2024.05.14.594194 — biophysics — Posted on 2024-05-15
2452 A new avian feeding mechanism: Nectar suction by sunbirds
Cuban, D.; Wang-Claypool, C.; Dalimunthe, Y.; Downs, C. T.; Bowie, R. C. K.; Brau, F.; Johnson, S.; Rico-Guevara, A.
10.1101/2024.05.14.594085 — biophysics — Posted on 2024-05-15
2455 OM2Seq: Learning retrieval embeddings for optical genome mapping
Nogin, Y.; Sapir, D.; Detinis Zur, T.; Weinberger, N.; Belinkov, Y.; Ebenstein, Y.; Shechtman, Y.
10.1101/2023.11.20.567868 — bioinformatics — Posted on 2024-05-15
2456 Recognition of RNA secondary structures with a programmable peptide nucleic acid-based platform
Lu, R.; Deng, L.; Lian, Y.; Ke, X.; Yang, L.; Xi, K.; Ong, A. A. L.; Chen, Y.; Zhou, H.; Meng, Z.; Lin, R.; Fan, S.; Liu, Y.; Toh, D.-F. K.; Zhan, X.; S. Krishna, M.; M. Patil, K.; Lu, Y.; Liu, Z.; Zhu, L.; Wang, H.; Li, G.; Chen, G.
10.1101/2024.05.14.594238 — biochemistry — Posted on 2024-05-15
2458 RudS: Bacterial Desulfidase Responsible for tRNA 4-Thiouridine De-modification
Jamontas, R.; Laurynenas, A.; Povilaityte, D.; Meskys, R.; Aucynaite, A.
10.1101/2024.05.15.593862 — biochemistry — Posted on 2024-05-15
2459 Dual-Action Kinase Inhibitors Control p38α MAP Kinase Threonine Dephosphorylation
Stadnicki, E.; Ludewig, H.; Kumar, R. P.; Wang, X.; Qiao, Y.; Kern, D.; Bradshaw, N.
10.1101/2024.05.15.594272 — biochemistry — Posted on 2024-05-15
2461 Moesin activation controls bone resorption and tunneling nanotube-dependent osteoclast fusion
Dufrancais, O.; Verdys, P.; Metais, A.; Juzans, M.; Sanchez, T.; Bergert, M.; Plozza, M.; Halper, J.; Panebianco, C. J.; Mascarau, R.; Gence, R.; Arnaud, G.; Ben Neji, M.; Maridonneau-Parini, I.; Le Cabec, V.; Boerckel, J. D.; Pavlos, N.; Diz-Munoz, A.; Lagarrigue, F.; Blin-Wakkach, C.; Carreno, S.; Poincloux, R.; Burkhardt, J. K.; Raynaud-Messina, B.; Verollet, C.
10.1101/2024.05.13.593799 — cell biology — Posted on 2024-05-15
2462 Hemin-induced platelet activation is regulated via ACKR3 chemokine surface receptor - implications for passivation of vulnerable atherosclerotic plaque
Laspa, Z.; Dicenta-Baunach, V.; Schaale, D.; Sigle, M.; Hochuli, R.; Castor, T.; Bayrak, A.; Harm, T.; Mueller, K. A. L.; Pillaiyar, T.; Laufer, S.; Rohfling, A.-K.; Gawaz, M.
10.1101/2024.05.13.593847 — cell biology — Posted on 2024-05-15
2463 Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
Crnkovic, S.; Thekkekara Puthenparampil, H.; Mulch, S.; Biasin, V.; Wilhelm, J.; Bartkuhn, M.; Bonyadi Rad, E.; Wawrzen, A.; Matzer, I.; Mitra, A.; Leib, R. D.; Nagy, B. M.; Sahu-Osen, A.; Valzano, F.; Bordag, N.; Evermann, M.; Hoetzenecker, K.; Olschewski, A.; Ljubojevic-Holzer, S.; Wygrecka, M.; Stenmark, K.; Marsh, L. M.; de Jesus Perez, V.; Kwapiszewska, G.
10.1101/2024.05.15.594343 — cell biology — Posted on 2024-05-15
2465 MEK signaling represents a viable therapeutic vulnerability of KRAS-driven somatic brain arteriovenous malformations
Suarez, C. F.; Harb, O. A.; Robledo, A.; Largoza, G.; Ahn, J. J.; Alley, E. K.; Wu, T.; Veeraragavan, S.; McClugage, S. T.; Iacobas, I.; Fish, J. E.; Kan, P. T.; Marrelli, S. P.; Wythe, J. D.
10.1101/2024.05.15.594335 — molecular biology — Posted on 2024-05-15
2466 Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model
Pont, S.; Nilly, F.; Berry, L.; Bonhoure, A.; Alford, M. A.; Louis, M.; Nogaret, P.; Lesouhaitier, O.; Hancock, R. E. W.; Plesiat, P.; Blanc-Potard, A.
10.1101/2024.05.15.594279 — microbiology — Posted on 2024-05-15
2467 Toxoplasma gondii from Gabonese forest, Central Africa: first report of an African wild population
Galal, L.; Fritz, M.; Becquart, P.; Passebosc-Faure, K.; Plault, N.; Boundenga, L.; Mombo, I. M.; Kombila, L. B.; Mebaley, T. N.; Lenguiyah, L. H.; Ngoubangoye, B.; N'Dilimabaka, N.; Leroy, E. M.; Maganga, G. D.; Mercier, A.
10.1101/2024.05.15.594283 — microbiology — Posted on 2024-05-15
2469 BIFROST: a method for registering diverse imagingdatasets of the Drosophila brain
Brezovec, B. E.; Berger, A. B.; Hao, Y. A.; Lin, A.; Ahmed, O. M.; Pacheco, D. A.; Thiberge, S. Y.; Murthy, M.; Clandinin, T. R.
10.1101/2023.06.09.544408 — neuroscience — Posted on 2024-05-15
2473 An efficient in vivo-inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies
Bjanes, E.; Stream, A.; Janssen, A. B.; Gibson, P. S.; Bravo, A. M.; Dahesh, S.; Baker, J. L.; Varble, A.; Nizet, V.; Veening, J.-W.
10.1101/2024.02.22.581527 — microbiology — Posted on 2024-05-15
2474 Surface Hydrophilicity Promotes Bacterial Twitching Motility
O'Hara, M. T.; Shimozono, T.; Dye, K. J.; Harris, D.; Yang, Z.
10.1101/2024.03.23.586342 — microbiology — Posted on 2024-05-15
2475 Internal regulation between constitutively expressed T cell coinhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants
Adegoke, A. O.; Thangavelu, G.; Chou, T.-F.; Petersen, M.; Kakugawa, K.; May, J.; Joannou, K.; Wang, Q.; Ellestad, K. K.; Boon, L.; Bretscher, P. A.; Cheroutre, H.; Kronenberg, M.; Baldwin, T. A.; Anderson, C. C.
10.1101/2024.01.10.574913 — immunology — Posted on 2024-05-15
2481 This microtubule does not exist: Super-resolution microscopy image generation by a diffusion model
Saguy, A.; Nahimov, T.; Lehrman, M.; Gomez-de-Mariscal, E.; Hidalgo-Cenalmor, I.; Alalouf, O.; Henriques, R.; Shechtman, Y.
10.1101/2023.07.06.548004 — bioengineering — Posted on 2024-05-15
2482 Delivery of A Jagged1-PEG-MAL hydrogel with Pediatric Human Bone Cells Regenerates Critically-Sized Craniofacial Bone Defects
Kamalakar, A.; Tobin, B.; Kaimari, S.; Robinson, M. H.; Toma, A. I.; Cha, T.; Chihab, S.; Moriarity, I.; Gautam, S.; Bhattaram, P.; Abramowicz, S.; Drissi, H.; Garcia, A.; Wood, L.; Goudy, S. L.
10.1101/2023.10.06.561291 — developmental biology — Posted on 2024-05-15
2483 Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape
Santinello, B.; Sun, R.; Amjad, A.; Hoyt, S. J.; Ouyang, L.; Courret, C.; Drennan, R.; Leo, L.; Larracuente, A. M.; Core, L.; O'Neill, R. J.; Mellone, B. G.
10.1101/2024.01.14.574223 — cell biology — Posted on 2024-05-15
2484 Action prediction error: a value-free dopaminergic teaching signal that drives stable learning
Greenstreet, F.; Vergara, H. M.; Johansson, Y.; Pati, S.; Schwarz, L.; Lenzi, S. C.; Wisdom, M.; Gubanova, A.; Marbach, F.; Rollik, L.; Kaur, J.; Moskovitz, T.; Cohen, J.; Thompson, E.; Clopath, C. M.; Margrie, T. W.; Stephenson-Jones, M.
10.1101/2022.09.12.507572 — neuroscience — Posted on 2024-05-15
2486 Efficient and durable gene activation by Cas9-mediated epigenome editing in vivo
Qin, Y.; Akbulut, T.; Mandraju, R.; Connolly, K.; Bechill, J.; Assadian, F.; Shottek, A.; Levy, S.; Benoit, J.; Yamagata, T.
10.1101/2024.05.03.592438 — bioengineering — Posted on 2024-05-15
2488 Regulatory T cells restrain skin inflammation by modulating peripheral neuron activation
Mendoza, A.; Bou-Puerto, R.; Giovanelli, P.; Dikiy, S.; Andretta, E.; Rudensky, A.
10.1101/2024.05.14.594055 — immunology — Posted on 2024-05-15
2489 A fungal plant pathogen overcomes mlo-mediated broad-spectrum disease resistance by rapid gene loss
Kusch, S.; Frantzeskakis, L.; Lassen, B. D.; Kümmel, F.; Pesch, L.; Barsoum, M.; Walden, K. D.; Panstruga, R.
10.1101/2021.12.09.471931 — plant biology — Posted on 2024-05-15
2490 plantMASST - Community-driven chemotaxonomic digitization of plants
Gomes, P. W. P.; Mannochio-Russo, H.; Schmid, R.; Zuffa, S.; Damiani, T.; Quiros-Guerrero, L.-M.; Caraballo-Rodriguez, A. M.; Zhao, H. N.; Yang, H.; Xing, S.; Charron-Lamoureux, V.; Chigumba, D. N.; Sedio, B. E.; Myers, J. A.; Allard, P.-M.; Harwood, T. V.; Tamayo-Castillo, G.; Kang, K. B.; Defossez, E.; Koolen, H. H. F.; da Silva, M. N.; e Silva, C. Y. Y.; Rasmann, S.; Walker, T. W. N.; Glauser, G.; Chaves-Fallas, J. M.; David, B.; Kim, H.; Lee, K. H.; Kim, M. J.; Choi, W. J.; Keum, Y.-S.; de Lima, E. J. S. P.; de Medeiros, L. S.; Bataglion, G. A.; Costa, E. V.; da Silva, F. M. A.; Carvalho,
10.1101/2024.05.13.593988 — plant biology — Posted on 2024-05-15
2492 Clonal determinants of organotropism and survival in metastatic uveal melanoma
Jones, B. S.; Demkowicz, P. C.; Matesva, M.; Lim, R. P.; Sinard, J. H.; Bacchiocchi, A.; Halaban, R.; Bosenberg, M.; Sznol, M.; Kluger, H. M.; Bakhoum, M. F.
10.1101/2024.05.14.593919 — cancer biology — Posted on 2024-05-15
2494 CAIM: Coverage-based Analysis for Identification of Microbiome
Acheampong, D. A.; Jenjaroenpun, P.; Wongsurawat, T.; Krulilung, A.; Pomyen, Y.; Kandel, S.; Kunadirek, P.; Chuaypen, N.; Kusonmano, K.; Nookaew, I.
10.1101/2024.04.25.591018 — bioinformatics — Posted on 2024-05-15
2496 Multimodal analysis of RNA sequencing data powers discovery of complex trait genetics
Munro, D.; Ehsan, N.; Esmaeili-Fard, S. M.; Gusev, A.; Palmer, A. A.; Mohammadi, P.
10.1101/2024.05.14.594051 — genetics — Posted on 2024-05-15
2498 The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease
Barzegar Behrooz, A.; Aghanoori, M.; Khodagholi, F.; Nazari, M.; Latifi Navid, H.; Vosoghian, F.; Anjomani, M.; Lotfi, J.; Ahmadiani, A.; Eliassi, A.; Nabavizadeh, F.; Soleimani, E.; Ghavami, S.; Fahanik Babaei, J.
10.1101/2024.05.12.593775 — cell biology — Posted on 2024-05-15
2499 Pericytes mediate neurovascular remodeling in chronic arterial hypertension
Morton, L.; Garza, A. P.; Debska-Vielhaber, G.; Villafuerte, L. E.; Henneicke, S.; Arndt, P.; Meuth, S. G.; Schreiber, S.; Dunay, I. R.
10.1101/2024.05.13.594041 — neuroscience — Posted on 2024-05-15
2500 ThermoMaze: A behavioral paradigm for readout of immobility-related brain events
Voroslakos, M.; Zhang, Y.; McClain, K.; Huszar, R.; Rothstein, A.; Buzsaki, G.
10.1101/2023.07.25.550518 — neuroscience — Posted on 2024-05-15
2502 Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults
Schommartz, I.; Lembcke, P. F.; Ortiz-Tudela, J.; Bauer, M.; Kaindl, A. M.; Buss, C.; Shing, Y. L.
10.1101/2023.05.11.540422 — neuroscience — Posted on 2024-05-15
2503 Renal Proximal Tubule Cell-specific Megalin Deletion Induces Tubulointerstitial Nephritis in Mice Fed Western Diet
Amioka, N.; Franklin, M. K.; Kukida, M.; Sawada, H.; Moorleghen, J. J.; Howatt, D. A.; Katsumata, Y.; Mullick, A. E.; Yanagita, M.; Martinez-Irizarry, M.; Sandoval, R. M.; Dunn, K. W.; Daugherty, A.; Lu, H. S.
10.1101/2024.05.11.592234 — pathology — Posted on 2024-05-15
2505 Birds affected by a 2021 avian mortality event are strongly associated with supplemental feeding and ground foraging behaviors
Yala, A. J.; Baillargeon, T.; Gordon, L.; Greening, S.; Mwakibete, L.; Sevigny, J.; Burrell, C.; Casey, C.; Driscoll, C.; Klein, P.; Lewis, N.; Murphy, L.; Poppenga, R.; Thomas, K.; Yabsley, M.; Gagne, R. B.; Nemeth, N.; Tato, C.; Needle, D.; Ogbunugafor, C. B.
10.1101/2024.05.14.593614 — ecology — Posted on 2024-05-15
2506 Birds affected by a 2021 avian mortality event are strongly associated with supplemental feeding and ground foraging behaviors
Ayala, A. J.; Baillargeon, T.; Gordon, L.; Greening, S.; Mwakibete, L.; Sevigny, J.; Burrell, C.; Casey, C.; Driscoll, C.; Klein, P.; Lewis, N.; Murphy, L.; Poppenga, R.; Thomas, K.; Yabsley, M.; Gagne, R. B.; Nemeth, N.; Tato, C.; Needle, D.; Ogbunugafor, C. B.
10.1101/2024.05.14.593614 — ecology — Posted on 2024-05-15
2507 Peroxiredoxin 2 Regulates DAF-16/FOXO Mediated Mitochondrial Remodelling in Response to Exercise that is Disrupted in Ageing
Xia, Q.; Li, P.; Casas-Martinez, J. C.; Miranda-Vizuete, A.; McDermott, E.; Dockery, P.; Goljanek-Whysall, K.; McDonagh, B.
10.1101/2024.05.13.593975 — molecular biology — Posted on 2024-05-15
2508 PPFlow: Target-aware Peptide Design with Torsional Flow Matching
Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.
10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-05-15
2509 Transcriptional Control of Neocortical Size and Microcephaly
Barao, S.; Xu, Y.; Llongueras, J. P.; Vistein, R.; Goff, L.; Nielsen, K.; Bae, B.-I.; Smith, R. S.; Walsh, C. A.; Stein O Brien, G.; Muller, U.
10.1101/2023.11.02.565322 — neuroscience — Posted on 2024-05-15
2510 Allelic variants confer Arabidopsis adaptation to mild environmental clines
Wijfjes, R. Y.; Boesten, R.; Becker, F. F. M.; Theeuwen, T. P. J. M.; Snoek, B. L.; Mastoraki, M.; Verheijen, J. J.; Guvencli, N.; Denkers, L.-A. M.; Koornneef, M.; van Eeuwijk, F. A.; Smit, S.; de Ridder, D.; Aarts, M. G. M.
10.1101/2023.09.18.558200 — plant biology — Posted on 2024-05-15
2511 Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgia, and rescues mice from a negative behavioural phenotype in experimental endometriosis
Higgins, B.; Simitsidellis, I.; Zheng, X.; Collins, F.; Homer, N.; Denham, S.; Simpson, J.; Millar, M.; Boswell, L.; Lee, H. Y.; Kim, Y. G.; Park, K. H.; Park, L. C.; Sweeney, P. J.; Feraille, G.; Taddei, A.; Chagras, D.; Alvarez, T.; Webster, S. P.; Horne, A. W.; Saunders, P. T.; Mole, D. J.
10.1101/2024.05.13.593856 — pathology — Posted on 2024-05-15
2512 Genome-wide association for loci influencing thermal performance curves in Neurospora crassa
Rasanen, E.; Moghadam, N. N.; Sidhu, K.; Summanen, P. A. M.; Littunen, H.-R.; Ketola, T.; Kronholm, I.
10.1101/2024.04.29.591604 — genetics — Posted on 2024-05-15
2514 Fifty shades of The Virtual Brain: Converging optimal working points yield biologically plausibleelectrophysiological and imaging features
Triebkorn, P.; Meier, J.; Zimmermann, J.; Stefanovski, L.; Roy, D.; Solodkin, A.; Jirsa, V.; Deco, G.; Breakspear, M.; Schirner, M.; McIntosh, A. R.; Ritter, P.
10.1101/2020.03.26.009795 — neuroscience — Posted on 2024-05-15
2515 Graded multidimensional clinical and radiological variation in patients with Alzheimer's disease and posterior cortical atrophy
Ingram, R. U.; Ocal, D.; Halai, A. D.; Pobric, G.; Cash, D.; Crutch, S. J.; Yong, K. X. X.; Lambon Ralph, M. A.
10.1101/2023.02.07.527424 — neuroscience — Posted on 2024-05-15
2516 Metabolic heterogeneity of colorectal cancer as a prognostic factor: insights gained from fluorescence lifetime imaging
Komarova, A. D.; Sinyushkina, S. D.; Shchechkin, I. D.; Druzhkova, I. N.; Smirnova, S. A.; Terekhov, V. M.; Mozherov, A. M.; Ignatova, N. I.; Nikonova, E. E.; Shirshin, E. A.; Shimolina, L. E.; Gamayunov, S. V.; Shcheslavskiy, V. I.; Shirmanova, M. V.
10.1101/2024.01.02.573874 — cancer biology — Posted on 2024-05-15
2517 Cluster efficient pangenome graph construction with nf-core/pangenome
Heumos, S.; Heuer, M. L.; Hanssen, F.; Heumos, L.; Guarracino, A.; Heringer, P.; Ehmele, P.; Prins, P.; Garrison, E.; Nahnsen, S.
10.1101/2024.05.13.593871 — bioinformatics — Posted on 2024-05-15
2521 The complete genome of lettuce reveals centromere landscape and empowers breeding
Wang, K.; Jin, J.; Wang, J.; Wang, X.; Sun, J.; Meng, D.; Wang, X.; Guo, L.
10.1101/2024.05.14.593296 — genomics — Posted on 2024-05-15
2523 Variability in mineral composition of Canadian lentil cultivars
Vargas, A.; Podder, R.; Subedi, M.; Bett, K.; Vandenberg, A.
10.1101/2024.05.14.592802 — genetics — Posted on 2024-05-15
2527 Passive accumulation of alkaloids in putatively non-toxic frogs challenges paradigms of the origins of acquired chemical defenses
Tarvin, R. D.; Coleman, J. L.; Donoso, D. A.; Betancourth-Cundar, M.; Lopez-Hervas, K.; Gleason, K. S.; Sanders, J. R.; Smith, J. M.; Ron, S. R.; Santos, J. C.; Sedio, B. E.; Cannatella, D. C.; Fitch, R.
10.1101/2024.05.13.593697 — evolutionary biology — Posted on 2024-05-15
2528 Diurnal butterfly diversity in a human-modified landscape of the subtropical montane forest of NW Argentina
Guanuco, A. d. V.; Ordano, M.; Pereyra, L. C.; Barrionuevo, M. J.; Gonzalez Baffa Trasci, N. V.; Vaira, M.
10.1101/2024.05.14.592973 — ecology — Posted on 2024-05-15
2529 Effect of developmental and adult diet composition on reproductive aging in Drosophila melanogaster
Ruchitha, B. G.; Kumar, D.; Chandrakanth, M.; Farooq, I.; Kumar, N.; Sura, C.; Chetan, S.; Tung, S.
10.1101/2024.05.14.589018 — ecology — Posted on 2024-05-15
2530 Birds affected by a 2021 avian mortality event are strongly associated with supplemental feeding and ground foraging behaviors
Yala, A. J.; Baillargeon, T.; Gordon, L.; Greening, S.; Mwakibete, L.; Sevigny, J.; Shearn-Bochsler, V.; Burrell, C.; Casey, C.; Driscoll, C.; Klein, P.; Lewis, N.; Murphy, L.; Poppenga, R.; Thomas, K.; Yabsley, M.; Gagne, R. B.; Nemeth, N.; Tato, C.; Needle, D.; Ogbunugafor, C. B.
10.1101/2024.05.14.593614 — ecology — Posted on 2024-05-15
2533 Longitudinal proteomic analysis of T cell differentiation in vivo reveals dynamic changes of the interactome
Beusch, C. M.; Dawood, A. S.; Ozdilek, A.; Welbourn, S. L.; Flegle, A.; Malik, S.; Niavi, C.; Akhtar, A.; Roman, C.; Gavora, A. A.; Gordon, D. E.; Abdel-Hakeem, M. S.
10.1101/2024.05.14.593504 — immunology — Posted on 2024-05-15
2537 Methods to Utilize Pulse Wave Velocity to Measure Alterations in Cerebral and Cardiovascular Parameters
Marshall, A. G.; Neikirk, K.; Shao, B.; Crabtree, A.; Vue, Z.; Beasley, H. K.; Garza-Lopez, E.; Scudese, E.; Wanjalla, C. N.; Kirabo, A.; Albritton, C.; Jamison, S.; Demirci, M.; Murray, S.; Cooper, A.; Taffet, G.; Hinton, A.; Reddy, A. K.
10.1101/2023.06.22.546154 — physiology — Posted on 2024-05-15
2539 Targeted Degradation of CDK9 Potently Disrupts the MYC Transcriptional Network
Toure, M. A.; Motoyama, K.; Xiang, Y.; Urgiles, J.; Kabinger, F.; Koglin, A.-S.; Iyer, R. S.; Gagnon, K.; Kumar, A.; Ojeda, S.; Harrison, D. A.; Rees, M. G.; Roth, J. A.; Ott, C. J.; Schiavoni, R.; Whittaker, C. A.; Levine, S. S.; White, F. M.; Calo, E.; Richters, A.; Koehler, A. N.
10.1101/2024.05.14.593352 — cancer biology — Posted on 2024-05-15
2541 Discriminative histone imputation using chromatin accessibility
Wen, W.; Zhong, J.; Zhang, Z.; Jia, L.; Chu, T.; Wang, N.; Danko, C. G.; Wang, Z.
10.1101/2024.01.11.575175 — bioinformatics — Posted on 2024-05-15
2544 Graded multidimensional clinical and radiological variation in patients with Alzheimer's disease and posterior cortical atrophy
Ingram, R. U.; Ocal, D.; Halai, A. D.; Pobric, G.; Cash, D.; Crutch, S. J.; Yong, K. X. X.; Lambon Ralph, M. A.
10.1101/2023.02.07.527424 — neuroscience — Posted on 2024-05-15
2545 Pooled genetic screens identify breast cancer risk genes involved in evasion from T cell-mediated killing
Shi, W.; Luo, Y.; Burrows, J. M.; Black, D.; Civitarese, A.; Perlaza-Jimenez, L.; Zhang, P.; Manning, M.; Tuano, N.; Renteria, M. E.; Xiao, C.; Tey, S.-K.; Rosenbluh, J.; Smith, C.; Chenevix-Trench, G.; Beesley, J.
10.1101/2024.05.10.593465 — genetics — Posted on 2024-05-15
2546 PPFlow: Target-aware Peptide Design with Torsional Flow Matching
Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.
10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-05-15
2549 Deconvolution of polygenic risk score in single cells unravels cellular and molecular heterogeneity of complex human diseases
Zhang, S.; Shu, H.; Zhou, J.; Rubin-Sigler, J.; Yang, X.; Liu, Y.; Cooper-Knock, J.; Monte, E.; Zhu, C.; Tu, S.; Li, H.; Tong, M.; Ecker, J.; Ichida, J.; Shen, Y.; Zeng, J.; Tsao, P.; Snyder, M.
10.1101/2024.05.14.594252 — genetics — Posted on 2024-05-14
2552 Partitioning biota along the Elbe River estuary: where are the community transitions?
Branoff, B.; Grueterich, L.; Wilson, M.; Tobias-Hunefeldt, S. P.; Saadaoui, Y.; Mittmann-Goetsch, J.; Neiske, F.; Lexmond, F.; Becker, J.; Grossart, H.-P.; Porada, P.; Streit, W.; Eschenbach, A.; Kutzbach, L.; Jensen, K.
10.1101/2024.05.13.593883 — ecology — Posted on 2024-05-14
2554 Time of first contact determines cooperator success in a cross-feeding consortium
Los, R.; Fecker, T.; van Touw, P. A. M.; van Tatenhove-Pel, R. J.; Idema, T.
10.1101/2024.05.13.593921 — ecology — Posted on 2024-05-14
2555 Recurrent extreme climatic events are driving gorgonian populations to local extinction: low adaptive potential to marine heatwaves.
Ramirez-Calero, S.; Gomez-Gras, D.; Barreiro, A.; Bensoussan, N.; Figuerola-Ferrando, L.; Jou, M.; Lopez-Sanz, A.; Lopez-Sendino, P.; Medrano, A.; Montero-Serra, I.; Pages-Escola, M.; Linares, C.; Ledoux, J.-B.; Garrabou, J.
10.1101/2024.05.13.593802 — ecology — Posted on 2024-05-14
2556 The roles of isolation and interspecific interaction in generating the functional diversity of an insular mammal radiation
Nations, J. A.; Kohli, B. A.; Handika, H.; Achmadi, A. S.; Polito, M. J.; Rowe, K. C.; Esselstyn, J. A.
10.1101/2022.07.15.500274 — ecology — Posted on 2024-05-14
2561 Successful Cardiac Resynchronization Therapy Reduces Negative Septal Work in Patient-Specific Models of Dyssynchronous Heart Failure
Craine, A.; Krishnamurthy, A.; Villongco, C. T.; Vincent, K.; Krummen, D. E.; Narayan, S. M.; Kerckhoffs, R. C. P.; Omens, J. H.; Contijoch, F.; McCulloch, A. D.
10.1101/2024.05.13.593804 — bioengineering — Posted on 2024-05-14
2562 Exogenous lipid vesicles induce endocytosis-mediated cellular aggregation in a close unicellular relative of animals
Kidner, R. Q.; Goldstone, E. B.; Rodefeld, H. J.; Brokaw, L. P.; Gonzalez, A. M.; Ros-Rocher, N.; Gerdt, J. P.
10.1101/2024.05.14.593945 — biochemistry — Posted on 2024-05-14
2563 Structure-activity relationship of pyrrolidine pentamine derivatives as inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib
Tran, T.; Ramirez, M. S.; Donow, H. M.; Magana, A. J.; LaVoi, T.; Mamun, Y.; Chapagain, P. P.; Santos, R.; Pinilla, C.; Giulianotti, M. A.; Tolmasky, M. E.
10.1101/2024.05.14.594018 — biochemistry — Posted on 2024-05-14
2565 Stimulatory and inhibitory G-protein signaling relays drive cAMP accumulation for timely metamorphosis in the chordate Ciona
Hozumi, A.; Totsuka, N. M.; Onodera, A.; Wang, Y.; Hamada, M.; Shiraishi, A.; Satake, H.; Horie, T.; Hotta, K.; Sasakura, Y.
10.1101/2024.04.09.588679 — developmental biology — Posted on 2024-05-14
2566 Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation
Miao, Y.; Du, Y.; Wang, B.; Liang, J.; Liang, Y.; Dang, S.; Liu, J.; Li, D.; He, K.; Ding, M.
10.1101/2024.01.10.575034 — cell biology — Posted on 2024-05-14
2567 Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction
Ihara, J.; Huang, Y.; Takami, Y.; Nozato, Y.; Takahashi, T.; Kakino, A.; Wang, C.; Wang, Z.; Guo, Y.; Liu, W.; Yin, N.; Ohara, R.; Fujimoto, T.; Yoshida, S.; Hongyo, K.; Koriyama, H.; Akasaka, H.; Takeshita, H.; Sakai, S.; Inoue, K.; Isaka, Y.; Rakugi, H.; Sawamura, T.; Yamamoto, K.
10.1101/2024.05.13.594020 — molecular biology — Posted on 2024-05-14
2568 Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions
Burns, G. W.; Fu, Z.; Vegter, E. L.; Madaj, Z. B.; Greaves, E.; Flores, I.; Fazleabas, A. T.
10.1101/2024.03.23.586434 — molecular biology — Posted on 2024-05-14
2570 SARS-CoV-2 Infection of Salivary Glands Predisposes to Oral Candidiasis
Alfaifi, A. A.; Wang, T. W.; Perez, P.; Sultan, A. A.; Meiller, T. F.; Rock, P.; Kleiner, D.; Chertow, D. S.; Hewitt, S.; Gasmi, B.; Stein, S.; Ramelli, S.; Martin, D.; Warner, B.; Jabra-Rizk, M. A.
10.1101/2024.05.13.593942 — microbiology — Posted on 2024-05-14
2571 Life on the edge: microbial diversity, resistome, and virulome in soils from the Union Glacier cold desert
Arros, P.; Palma, D.; Galvez-Silva, M.; Gaete, A.; Gonzalez, H.; Carrasco, G.; Coche, J.; Perez, I.; Gallardo-Cerda, J.; Castro-Nallar, E.; Galban, C.; Varas, M. A.; Campos, M.; Acuna, J.; Jorquera, M.; Chavez, F. P.; Cambiazo, V.; Marcoleta, A. E.
10.1101/2024.05.13.594038 — microbiology — Posted on 2024-05-14
2572 The Neosartorya (Aspergillus) fischeri antifungal protein NFAP2 has low potential to trigger resistance development in Candida albicans in vitro
Bende, G.; Zsindely, N.; Laczi, K.; Kristoffy, Z.; Papp, C.; Farkas, A.; Toth, L.; Saringer, S.; Bodai, L.; Rakhely, G.; Marx, F.; Galgoczy, L.
10.1101/2024.05.14.594093 — microbiology — Posted on 2024-05-14
2573 Novel Oral Adjuvant to Enhance Cytotoxic Memory-Like NK Cell Responses in an HIV Vaccine Platform
Liyanage, N. M.; Alles, M.; Gunasena, M.; Isckarus, C.; De Silva, I.; Board, S.; Mulhern, W.; Collins, P.; Demberg, T.
10.1101/2024.05.11.593683 — immunology — Posted on 2024-05-14
2574 Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics
Liu, Y.; Yin, M.; Mao, X.; Wu, S.; Wei, S.; Heng, S.; Yang, Y.; Huang, J.; Guo, Z.; Li, C.; Ji, C.; Hu, L.; Liu, W.; Zhang, L.-j.
10.1101/2024.01.16.575925 — immunology — Posted on 2024-05-14
2577 Spontaneous movements and their impact on neural activity fluctuate with latent engagement states
Yin, C.; Melin, M.; Rojas-Bowe, G.; Couto, J.; Sun, X.; Gluf, S.; Kostiuk, A.; Musall, S.; Churchland, A. K.
10.1101/2023.06.26.546404 — neuroscience — Posted on 2024-05-14
2578 Rapid, biochemical tagging of cellular activity history in vivo
Zhang, R.; Anguiano, M.; Aarrestad, I. K.; Lin, S.; Chandra, J.; Vadde, S. S.; Olson, D. E.; Kim, C. K.
10.1101/2023.09.06.556431 — neuroscience — Posted on 2024-05-14
2579 Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns
Saiki-Ishikawa, A.; Agrios, M.; Savya, S.; Forrest, A.; Sroussi, H.; Hsu, S.; Basrai, D.; Xu, F.; Miri, A.
10.1101/2023.09.23.559136 — neuroscience — Posted on 2024-05-14
2580 A Kv2 inhibitor combination reveals native neuronal conductances consistent with Kv2/KvS heteromers
Stewart, R. G.; Marquis, M. J.; Jo, S.; Aberra, A.; Cook, V.; Whiddon, Z.; Ferns, M.; Sack, J. T.
10.1101/2024.01.31.578214 — neuroscience — Posted on 2024-05-14
2583 Engineered lysins to modulate human gut microbiome communities
Rodriguez, J. R. D.; Lu, W.; Papadopoulos, J.; Venturelli, O. S.; Romero, P. A.
10.1101/2024.05.14.594189 — synthetic biology — Posted on 2024-05-14
2584 Genetic code expansion, click chemistry, and light-activated PI3K reveal details of membrane protein trafficking downstream of receptor tyrosine kinases
Koh, D.-S.; Stratiievska, A.; Jana, S.; Otto, S. C.; Swanson, T. M.; Nhim, A.; Carlson, S.; Raza, M.; Naves, L. A.; Senning, E. N.; Mehl, R.; Gordon, S. E.
10.1101/2023.08.29.555449 — physiology — Posted on 2024-05-14
2586 CRISPR gene and transcriptome engineering (CRISPRgate) improves loss-of-function genetic screening approaches
Stadager, J.; Bernardini, C.; Hartmann, L.; May, H.; Wiepcke, J.; Kuban, M.; Najafova, Z.; Johnsen, S. A.; Legewie, S.; Traube, F. R.; Jude, J.; Rathert, P.
10.1101/2024.05.14.594135 — biochemistry — Posted on 2024-05-14
2587 Parallel phosphoproteomics and metabolomics map the global metabolic tyrosine phosphoproteome
Hillis, A.; Tamir, T.; Perry, G.; Asara, J. M.; Johnson, J.; Yaron, T.; Cantley, L.; White, F.; Toker, A.
10.1101/2024.05.14.594136 — biochemistry — Posted on 2024-05-14
2589 Low copy CRISPR-Cas13d mitigates collateral RNA cleavage
Hart, S.; Wessels, H.-H.; Mendez-Mancilla, A.; Muller, S.; Drabavicius, G.; Choi, O.; Sanjana, N. E.
10.1101/2024.05.13.594039 — genomics — Posted on 2024-05-14
2590 Embryonic diversification of adult neural stem cells and ependymal cells
Yamaguchi, S.; Kuniya, T.; Omiya, H.; Suzuki, Y.; Seki, M.; Ukai, H.; Fang, L.; Harada, Y.; Kawaguchi, D.; Gotoh, Y.
10.1101/2024.05.12.593751 — developmental biology — Posted on 2024-05-14
2592 Asymmetric Engagement of Dimeric CRL3KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes
Yeo, M. J.; Zhang, O.; Xie, X.; Nam, E.; Payne, N. C.; Gosavi, P. M.; Kwok, H. S.; Iram, I.; Lee, C.; Li, J.; Chen, N. J.; Jiang, H.; Wang, Z. A.; Lee, K.; Mao, H.; Harry, S. A.; Barakat, I. A.; Takahashi, M.; Waterbury, A. L.; Barone, M.; Mattevi, A.; Bar-Peled, L.; Cole, P. A.; Mazitschek, R.; Liau, B. B.; Zheng, N.
10.1101/2024.05.14.593897 — molecular biology — Posted on 2024-05-14
2593 KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes
Xie, X.; Zhang, O.; Yeo, M. J.; Lee, C.; Harry, S. A.; Paul, L.; Li, Y.; Payne, N. C.; Nam, E.; Kwok, H. S.; Jiang, H.; Mao, H.; Hadley, J. L.; Lin, H.; Batts, M.; Gosavi, P. M.; D'Angiolella, V.; Cole, P. A.; Mazitschek, R.; Northcott, P. A.; Zheng, N.; Liau, B. B.
10.1101/2024.05.14.593970 — molecular biology — Posted on 2024-05-14
2594 Hyperactive mTORC1/4EBP1 Signaling Dysregulates Proteostasis and Accelerates Cardiac Aging.
Zarzycka, W.; Kobak, K. A.; King, C. J.; Peelor, F. F.; Miller, B. F.; Chiao, Y. A.
10.1101/2024.05.13.594044 — molecular biology — Posted on 2024-05-14
2595 TRBP regulates poly(I:C)-mediated apoptotic pathway by modulating miRNA biogenesis
Azuma, S.; Nakano, Y.; Takahashi, T.; Onomoto, K.; Haraguchi, T.; Suzuki, Y.; Iba, H.; Yoneyama, M.; Asano, Y.; Ui-Tei, K.
10.1101/2024.05.14.594097 — molecular biology — Posted on 2024-05-14
2596 Chromosomal domain formation by archaeal SMC, a roadblock protein, and DNA structure
Yamaura, K.; Takemata, N.; Kariya, M.; Ishino, S.; Yamauchi, M.; Takada, S.; Ishino, Y.; Atomi, H.
10.1101/2024.05.14.594075 — molecular biology — Posted on 2024-05-14
2597 Inhibition of EGFR/ErbB does not protect against C. difficile toxin B
Siddiqi, U.; Lunnemann, H. M.; Childress, K. O.; Shupe, J. A.; Rutherford, S. A.; Farrow, M. A.; Washington, M. K.; Coffey, R. J.; Lacy, D. B.; Markham, N. O.
10.1101/2024.05.13.594035 — microbiology — Posted on 2024-05-14
2598 Circadian rhythms mediate malaria transmission potential
Bento, I.; Parrington, B.; Pascual, R.; Goldberg, A. S.; Wang, E.; Liu, H.; Zelle, M.; Takahashi, J. S.; Elias, J. E.; Mota, M. M.; Rijo-Ferreira, F.
10.1101/2024.05.14.594221 — microbiology — Posted on 2024-05-14
2601 Unique RNA replication characteristics and nucleocapsid protein expression may explain differences in the replication capacity of SARS-COV-2 lineages.
Correa, I. A.; de Souza, M. R. M.; da Silva, G. P. D.; Pimentel, A. B. S. V. M.; Calil, P. T.; Cunha, M. S.; Mariani, D.; Brindeiro, R. M.; Costa, S. M.; Simas, M. C. d. C.; Ota, V. A.; Pereira, E. C.; Siqueira, M. M.; Resende, P. C.; Galliez, R. M.; Faffe, D. S.; Silva, R. J.; Castineiras, T. M. P. P.; Tanuri, A. J.; da Costa, L. J.
10.1101/2024.05.14.594070 — microbiology — Posted on 2024-05-14
2604 Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures
Martinez Alvarez, J. A.; Bouchat, R.; Gallet de St Aurin, T.; Martinez, L. M.; Caspeta, L.; Telek, S.; Zicler, A.; Gosset, G.; Frank, D.
10.1101/2024.05.14.594082 — microbiology — Posted on 2024-05-14
2610 Stress hyperglycemia exacerbates inflammatory brain injury after stroke
Won, S. J.; Zhang, Y.; Butler, N. J.; Kim, K.; Mocanu, E.; Nzoutchoum, O. T.; Lakkaraju, R.; Davis, J.; Ghosh, S.; Swanson, R. A.
10.1101/2024.05.14.594195 — neuroscience — Posted on 2024-05-14
2615 A Lung Cancer Mouse Model Database
Cai, L.; Gao, Y.; DeBerardinis, R. J.; Acquaah-Mensah, G.; Aidinis, V.; Beane, J. E.; Biswal, S.; Chen, T.; Concepcion-Crisol, C. P.; Gruner, B. M.; Jia, D.; Jones, R.; Kurie, J. M.; Lee, M. G.; Lindahl, P.; Lissanu, Y.; Lorz Lopez, M. C.; Martinelli, R.; Mazur, P. K.; Mazzilli, S. A.; Mii, S.; Moll, H.; Moorehead, R.; Morrisey, E. E.; Ng, S. R.; Oser, M. G.; Pandiri, A. R.; Powell, C. A.; Ramadori, G.; Santos Lafuente, M.; Snyder, E.; Sotillo, R.; Su, K.-Y.; Taki, T.; Taparra, K.; Xia, Y.; van Veen, E.; Winslow, M. M.; Xiao, G.; Rudin, C. M.; Oliver, T. G.; Xie, Y.; Minna, J. D.
10.1101/2024.02.28.582577 — cancer biology — Posted on 2024-05-14
2616 Indexing All Life's Known Biological Sequences
Karasikov, M.; Mustafa, H.; Danciu, D.; Zimmermann, M.; Barber, C.; Ratsch, G.; Kahles, A.
10.1101/2020.10.01.322164 — bioinformatics — Posted on 2024-05-14
2618 Enabling functionality and translation fidelity characterization of mRNA-based vaccines with a platform-based, antibody-free mass spectrometry detection approach
Stiving, A. Q.; Roose, B. W.; Tubbs, C.; Haverick, M.; Gruber, A.; Rustandi, R. R.; Kuiper, J.; Schombs, M.; Schuessler, H.; Li, X.
10.1101/2024.05.14.594137 — biochemistry — Posted on 2024-05-14
2619 Enhanced Recognition of a Herbal Compound Epiberberine by a DNA Quadruplex-Duplex Structure
zhan, x.; Deng, l.; Lian, Y.; Shu, Z.; Xu, Y.; Mai, X.; Krishna, M. S.; Xiong, C.; Lu, R.; Wang, A.; Bai, S.; Xu, Y.; Ni, J.; Vandana, J.; Wang, Z.; Li, Y.; Sun, D.; Huang, S.; Liu, J.; Cheng, G.; Wu, S.; Chiang, C.-C.; Stjepanovic, G.; Jiang, C.; Shao, Y.; Chen, G.
10.1101/2024.05.14.594047 — biochemistry — Posted on 2024-05-14
2623 Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGT
Ong, Q.; Lim, L. T. R.; Goh, C.; Liao, Y.; Chan, S. E.; Lim, C. J. Y.; Kam, V.; Yap, J.; Tseng, T.; Desrouleaux, R.; Wang, L. C.; Ler, S. G.; Lim, S. L.; Kim, S.; Sobota, R. M.; Bennett, A. M.; Han, W.; Yang, X.
10.1101/2024.05.12.593740 — cell biology — Posted on 2024-05-14
2624 Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM
Fernandez-Ramirez, M. d. C.; Nguyen, B. A.; Singh, V.; Afrin, S.; Evers, B. M.; Bassett, P.; Wang, L.; Pekala, M.; Ahmed, Y.; Singh, P.; Canepa, J.; Wosztyl, A.; Li, Y.; Saelices, L.
10.1101/2024.05.14.594218 — molecular biology — Posted on 2024-05-14
2625 Omicron-specific naive B cell maturation alleviates immune imprinting induced by SARS-CoV-2 inactivated vaccine
Yisimayi, A.; Song, W.; Wang, J.; Jian, F.; Yu, Y.; Chen, X.; Xu, Y.; An, R.; Wang, Y.; Wang, J.; Sun, H.; Wang, P.; Yu, L.; Shao, F.; Jin, R.; Shen, Z.; Wang, Y.; Cao, Y.
10.1101/2024.05.13.594034 — immunology — Posted on 2024-05-14
2627 Automated segmentation of epilepsy surgical resection cavities: comparison of four methods to manual segmentation
Courtney, M. R.; Sinclair, B.; Neal, A.; Nicolo, J.-P.; Kwan, P.; Law, M.; O'Brien, T. J.; Vivash, L.
10.1101/2024.05.13.593855 — neuroscience — Posted on 2024-05-14
2628 Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
Geraghty, A. C.; Acosta-Alvarez, L.; Rotiroti, M. C.; Dutton, S.; O'Dea, M.; Woo, P.; Xu, H.; Shamardani, K.; Mancusi, R.; Ni, L.; Mulinyawe, S. B.; Kim, W. J.; Liddelow, S.; Majzner, R. G.; Monje, M.
10.1101/2024.05.14.594163 — neuroscience — Posted on 2024-05-14
2631 A toolbox for genetic targeting of the claustrum
tuberosa, j.; boillat, m.; Dal Col, J.; Marconi, L.; Codourey, J.; Mannino, L.; Georgiou, E.; Menoud, M.; Carleton, A.; Rodriguez, I.
10.1101/2024.05.13.593837 — neuroscience — Posted on 2024-05-14
2632 Cortical Dynamics during Contour Integration
He, D.; Yang, A.; Coates, D. R.; Ogmen, H.; Chung, S. T.
10.1101/2024.05.13.594033 — neuroscience — Posted on 2024-05-14
2633 Melanopsin ganglion cells in the mouse retina independently evoke pupillary light reflex
Bohl, J. M.; Hassan, A. R.; Sharpe, Z. J.; Kola, M.; Ayub, M.; Pandey, Y.; Shehu, A.; Ichinose, T.
10.1101/2024.05.14.594181 — neuroscience — Posted on 2024-05-14
2634 Task-irrelevant stimuli reliably boost phasic pupil-linked arousal but do not affect decision formation
Hebisch, J.; Ghassemieh, A.-C.; Zhecheva, E.; Brouwer, M.; van Gaal, S.; Schwabe, L.; Donner, T. H.; de Gee, J. W.
10.1101/2024.05.14.594080 — neuroscience — Posted on 2024-05-14
2640 An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology
Piantadosi, S. C.; Lee, M.-K.; Wu, M.; Huynh, H.; Avila, R.; Pizzano, C.; Zamorano, C. A.; Wu, Y.; Xavier, R.; Stanslaski, M.; Kang, J.; Thai, S.; Kim, Y.; Zhang, J.; Huang, Y.; Kozorovitskiy, Y.; Good, C.; Banks, A.; Rogers, J. A.; Bruchas, M. R.
10.1101/2024.05.14.594203 — neuroscience — Posted on 2024-05-14
2641 Shared spatial selectivity in early visual cortex and face-selective brain regions
Morsi, A. Y.; Chow-Wing-Bom, H. T.; Schwarzkopf, D. S.; Goffaux, V.; Dekker, T. M.; Greenwood, J. A.
10.1101/2024.05.14.594166 — neuroscience — Posted on 2024-05-14
2646 Successful Cardiac Resynchronization Therapy Reduces Negative Septal Work in Patient-Specific Models of Dyssynchronous Heart Failure
Craine, A.; Krishnamurthy, A.; Villongco, C. T.; Vincent, K.; Krummen, D. E.; Narayan, S. M.; Kerckhoffs, R. C. P.; Omens, J. H.; Contijoch, F.; McCulloch, A. D.
10.1101/2024.05.13.593804 — bioengineering — Posted on 2024-05-14
2651 Patterning, regulation, and role of FoxO/DAF-16 in the early embryo
Mauro, M. S.; Martin, S. L.; Dumont, J.; Shirasu-Hiza, M.; Canman, J. C.
10.1101/2024.05.13.594029 — developmental biology — Posted on 2024-05-14
2652 Phased ERK-responsiveness and developmental robustness regulate teleost skin morphogenesis
Ramkumar, N.; Richardson, C.; O'Brien, M.; Butt, F. A.; Park, J.; Chao, A. T.; Bagnat, M.; Poss, K.; Di Talia, S.
10.1101/2024.05.13.593750 — developmental biology — Posted on 2024-05-14
2653 Cell-matrix force transmission regulates the loss of naïve pluripotency in mouse embryonic stem cells.
Viswanadha, S.; Gomez-Gonzalez, M.; Labouesse, C.; Venturini, V.; Trepat, X.; Chalut, K.; Kechagia, Z.; Roca-Cusachs, P.
10.1101/2024.05.13.593501 — developmental biology — Posted on 2024-05-14
2655 Novel cell states arise in embryonic cells devoid of key reprogramming factors
Youlten, S. E.; Miao, L.; Hoppe, C.; Boswell, C. W.; Musaev, D.; Abdelmessih, M.; Krishnaswamy, S.; Tornini, V. A.; Giraldez, A. J.
10.1101/2024.05.13.593729 — developmental biology — Posted on 2024-05-14
2656 ERK inhibits Cic repressor function via multisite phosphorylation
Paul, S.; Ilkhani, K.; Strozewski, N.; Yang, L.; Denberg, D. W.; Christalin, W.; Shvartsman, S. Y.; Veraksa, A.
10.1101/2024.05.14.594119 — developmental biology — Posted on 2024-05-14
2661 BlueRecording: A Pipeline for the efficient calculation of extracellular recordings in large-scale neural circuit models
Tharayil, J. J.; Blanco Alonso, J.; Farcito, S.; Lloyd, B.; Cassara, A.; Schuermann, F.; Neufeld, E.; Kuster, N.; Reimann, M. W.
10.1101/2024.05.14.591849 — neuroscience — Posted on 2024-05-14
2662 Cone bipolar cell synapses generate transient versus sustained signals in parallel ON pathways of the mouse retina
Kuo, S. P.; Yu, W.-Q.; Srivastava, P.; Okawa, H.; Della Santina, L.; Berson, D. M.; Awatramani, G. B.; Wong, R. O.; Rieke, F.
10.1101/2024.05.13.593825 — neuroscience — Posted on 2024-05-14
2663 Early and widespread engagement of the cerebellum during hippocampal epileptiform activity
Streng, M. L.; Kottke, B. W.; Wasserman, E. M.; Zecker, L.; Luong, L.; Ebner, T.; Krook-Magnuson, E.
10.1101/2024.05.14.593969 — neuroscience — Posted on 2024-05-14
2670 Hijacking a dedicated entorhinal-hippocampal extinction circuit to remove traumatic memory
Lin, Z.-J.; Gu, X.; Gong, W.-K.; Wang, M.; Wu, Y.-J.; Wang, Q.; Wu, X.-R.; Zhao, X.-Y.; Zhu, M. X.; Wang, L.-Y.; Liu, Q.; Yuan, T.-F.; Li, W.-G.; Xu, T.-L.
10.1101/2024.05.13.593830 — neuroscience — Posted on 2024-05-14
2671 Nerve injury converts Schwann cells in a persisting repair state in human neuroma tissue
Deininger, S.; Schumacher, J.; Blechschmidt, A.; Song, J.; Klugmann, C.; Antoniadis, G.; Pedro, M. T.; Knoell, B.; Meyer zu Reckendorf, S.
10.1101/2024.05.13.593891 — neuroscience — Posted on 2024-05-14
2672 A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice
Lu, S.; Portela, I. D. J.; Martino, N.; Ramos, R. B.; Salinero, A.; Smith, R.; Zuloaga, K. L.; Adam, A. P.
10.1101/2024.03.03.583191 — neuroscience — Posted on 2024-05-14
2673 Prediction of antidepressant treatment response with thalamo-somatomotor functional connectivity revealed by generalizable stratification of depressed patients
Kashiwagi, Y.; Tokuda, T.; Takahara, Y.; Sakai, Y.; Yoshimoto, J.; Yamashita, A.; Yoshioka, T.; Ogawa, K.; Okada, G.; Okamoto, Y.; Kawato, M.; Yamashita, O.
10.1101/2024.05.11.593664 — neuroscience — Posted on 2024-05-14
2677 PIEZO acts in an intestinal valve to regulate swallowing in C. elegans
Park, Y.-J.; Yeon, J.; Cho, J.; Kim, D.-Y.; Bai, X.; Oh, Y.; Kim, J.; Nam, H.; Hwang, H.; Heo, W.; Kim, J.; Jun, S.; Lee, K.; Kang, K.; Kim, K.
10.1101/2024.05.14.594054 — neuroscience — Posted on 2024-05-14
2679 Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis
Landry, C. A.; Costanzo, J.; Neto, M. M.; Zatz, M.; Schaffer, A. E.; Hatzoglou, M.; Muotri, A. R.; Miranda, H. C.
10.1101/2024.05.13.594000 — neuroscience — Posted on 2024-05-14
2684 Volumetric mesoscopic electrophysiology: a new imaging modality for the non-human primate
Teichert, T.; Papp, L.; Vincze, F.; Burns, N.; Goodell, B.; Ahmed, Z.; Holmes, A.; Gray, C. M.; Chamanzar, M.; Gurnsey, K.
10.1101/2024.05.13.593946 — neuroscience — Posted on 2024-05-14
2685 Peripheral opioid tolerance involves skin keratinocytes and platelet-derived growth factor type B signaling
Posa, L.; Miracle, S. A.; MacDonald, A. K.; Gamble, M.; Albers, K. M.; Freyberg, Z.; Logan, R.; Puig, S.
10.1101/2024.05.14.594040 — neuroscience — Posted on 2024-05-14
2686 Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-damage-sensing-dependent Cell Protection
Centeno, D.; Farsinejad, S.; Kochetkova, E.; Volpari, T.; Gladych-Macioszek, A.; Klupczynska - Gabryszak, A.; Polotaye, T.; Greenberg, M.; Kung, D.; Hyde, E.; Alshehri, S.; Pavlovic, T.; Sullivan, W.; Plewa, S.; Vakifahmetoglu-Norberg, H.; Monsma, F. J.; Muller, P. A. J.; Matysiak, J.; Zaborowski, M.; DiFeo, A.; Norberg, E.; Andres-Martin, L.; Iwanicki, M.
10.1101/2023.02.24.529893 — cancer biology — Posted on 2024-05-14
2687 Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia
Rodems, B. J.; Sharma, S.; Baker, C. D.; Kaszuba, C. M.; Ito, T.; Liesveld, J. L.; Calvi, L. M.; Becker, M. W.; Jordan, C. T.; Ashton, J. M.; Bajaj, J.
10.1101/2024.05.11.593633 — cancer biology — Posted on 2024-05-14
2688 Development of a humanized anti-FABP4 monoclonal antibody for treatment of breast cancer
Hao, J.; Jin, R.; Yi, Y.; Jiang, X.; Yu, J.; Xu, Z.; Schnicker, N. J.; Chimenti, M. S.; Sugg, S. L.; Li, B.
10.1101/2024.05.12.593748 — cancer biology — Posted on 2024-05-14
2690 AAnet resolves a continuum of spatially-localized cell states to unveil tumor complexity
Venkat, A.; Youlten, S. E.; Perez San Juan, B.; Purcell, C.; Amodio, M.; Burkhardt, D. B.; Benz, A.; Holst, J.; McCool, C.; Mollbrink, A.; Lundeberg, J.; van Dijk, D.; Goldstein, L. D.; Kummerfeld, S.; Krishnaswamy, S.; Chaffer, C. L.
10.1101/2024.05.11.593705 — bioinformatics — Posted on 2024-05-14
2691 Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues
Gorashi, R. M.; Baddour, T.; Chittle, S. J.; Velez, N. E. F.; Wenning, M. A.; Anseth, K. S.; Mestroni, L.; Pena, B.; Guo, P.; Aguado, B. A.
10.1101/2024.05.13.593760 — bioengineering — Posted on 2024-05-14
2694 Climate resilience conserved in global germplasm repositories: Picking the most promising parents for agile plant breeding
Campbell, Q.; Castaneda-Alvarez, N.; Domingo, R.; Bishop-von Wettberg, E.; Runck, B.; Nandkangre, H.; McCormick, A.; Fumia, N.; Neyhart, J.; Kilian, B.; Wambugu, P.; Nyamongo, D.; Hubner, S.; Sitar, S.; Thompson, A.; Rieseberg, L.; Gore, M. A.; Kantar, M. B.
10.1101/2024.05.11.593573 — genomics — Posted on 2024-05-14
2697 Antennal sensilla diversity in diurnal and nocturnal fireflies (Coleoptera, Lampyridae)
Pacheco, Y.; Mann, E.; Da Silveira, L. F. L.; Bybee, S. M.; Branham, M. A.; McHugh, J. V.; Stanger-Hall, K. F.
10.1101/2024.05.12.593785 — evolutionary biology — Posted on 2024-05-14
2699 Proving a negative; estimating species 'Confidence in Absence for Decision-Making' (CIADM) using environmental DNA monitoring
Griffiths, N. P.; Hänfling, B.; Cattaneo, M.; Wright, R. M.; Macarthur, J. A.; Peixoto, S.; Bolland, J. D.
10.1101/2024.05.12.593768 — ecology — Posted on 2024-05-14
2700 Effect of a constant magnetic field on morphology and motility of cell with cytoskeleton-associated magnetic nanoparticles
Karavashkova, O.; Maltseva, A.; Minin, A. S.; Demin, A.; Tin, P.; Aitova, A.; Tsvelaya, V.; Latypova, A. A.; Zubarev, I.
10.1101/2024.05.12.593754 — cell biology — Posted on 2024-05-14
2701 Oligosaccharyltransferase is involved in targeting to ER-associated degradation
Shenkman, M.; Ogen-Shtern, N.; Patel, C.; Groisman, B.; Pasmanik-Chor, M.; Schermann, S. M.; Korner, R.; Lederkremer, G. Z.
10.1101/2024.05.12.593735 — cell biology — Posted on 2024-05-14
2702 MSLASpheroidStamp: 3d cell spheroids for everyone
Minin, A. S.; Semerikova, T.; Karavashkova, O.; Pozdina, V.; Tomilina, M.; Zubarev, I.
10.1101/2024.05.12.593682 — cell biology — Posted on 2024-05-14
2703 Antibiotic use in early life subsequently impairs MAIT cell-mediated immunity
Sobel, A. L.; Melamed, J.; Haas, D.; LeBlanc, G.; Cirone, A.; Constantinides, M. G.
10.1101/2024.05.10.593643 — immunology — Posted on 2024-05-14
2704 Cortical evoked activity is modulated by the sleep state in a ferret model of tinnitus. A case study.
Milinski, L.; Nodal, F. R.; Emmerson, M. K. J.; King, A. J.; Vyazovskiy, V. V.; Bajo, V. M.
10.1101/2024.05.12.593782 — neuroscience — Posted on 2024-05-14
2705 Frontal theta power prospectively associated with response inhibition
van Rooij, D.; van Bijnen, S.; Schutte, I.; van der Stoep, N.; Kenemans, L.
10.1101/2024.05.13.593803 — neuroscience — Posted on 2024-05-14
2708 Processing of auditory feedback in perisylvian and insular cortex
Kurteff, G. L.; Field, A. M.; Asghar, S.; Tyler-Kabara, E. C.; Clarke, D.; Weiner, H. L.; Anderson, A. E.; Watrous, A. J.; Buchanan, R. J.; Modur, P. N.; Hamilton, L. S.
10.1101/2024.05.14.593257 — neuroscience — Posted on 2024-05-14
2710 Total testosterone is not associated with muscle mass, function or exercise adaptations in pre-menopausal females
Alexander, S. E.; Gatto, B.; Knowles, O. E.; Williams, R. M.; Fiebig, K. N.; Jansons, P.; Della Gatta, P. A.; Garnham, A.; Eynon, N.; Wadley, G. D.; Aisbett, B.; Hiam, D.; Lamon, S.
10.1101/2024.05.12.593786 — physiology — Posted on 2024-05-14
2712 The dual resistance mechanism of CYP325G4 and CYP6AA9 in Culex pipiens pallens legs according to transcriptome and proteome analysis
Xu, Y.; Du, J.; Zhang, K.; Li, J.; Zou, F.; Li, X.; Meng, Y.; Chen, Y.; Tao, L.; Zhao, F.; Ma, L.; Shen, B.; Zhou, D.; Sun, Y.; Yan, G.; Zhu, C.
10.1101/2024.05.13.593821 — physiology — Posted on 2024-05-14
2713 Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction
Hara, N.; Raclawska, D. S.; Morgan, L. E.; Needell, J. C.; Dao, L.; Kato, A.; Jaramillo, A. M.; Hume, P. S.; Holguin, F.; Janssen, W. J.; Vladar, E. K.; Evans, C. M.
10.1101/2024.05.10.593580 — physiology — Posted on 2024-05-14
2714 Epigenetic upregulation of carotid body angiotensin signaling increases blood pressure
Ahu, F.; McSwiggin, H.; Zyuzin, J.; Liu, J.; Yan, W.; Rehan, V.; Jendzjowsky, N.
10.1101/2024.05.10.593589 — physiology — Posted on 2024-05-14
2716 Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
Gounis, M.; Campos, A.; Shokry, E.; Mitchell, L.; Dornier, E.; Rooney, N.; Dhayade, S.; Pardo, L.; Moore, M.; Novo, D.; Mowat, J.; Jamieson, C.; Kay, E.; Zanivan, S.; Nixon, C.; Macpherson, I.; Tardito, S.; Sumpton, D.; Blyth, K.; Norman, J. C.; Clarke, C.
10.1101/2024.05.12.593552 — cancer biology — Posted on 2024-05-14
2718 The yolk sac vasculature in early avian embryo provides a novel model for the analysis of cancer extravasation
Morita, M.; Fujii, R.; Ryuno, A.; Morimoto, M.; Inoko, A.; Inoue, T.; Ikenouchi, J.; Atsuta, Y.; Hayashi, Y.; Teramoto, T.; Saito, D.
10.1101/2024.05.12.593798 — cancer biology — Posted on 2024-05-14
2719 Decoding the molecular interplay of endogenous CD20 and Rituximab with fast volumetric nanoscopy
Sauer, M.; Ghosh, A.; Meub, M.; Helmerich, D. A.; Doose, S.; Eiring, P.; Kortuem, K. M.
10.1101/2023.10.09.561472 — biophysics — Posted on 2024-05-14
2720 ATTRv-V30M Type A amyloid fibrils from the heart and nerves exhibit structural homogeneity.
Nguyen, B. A.; Afrin, S.; Yakubovska, A.; Singh, V.; Vaquer-Alicea, J.; Kunach, P.; Singh, P.; Pekala, M.; Ahmed, Y.; Fernandez-Ramirez, M. d. C.; Cabrera Hernandez, L.; Pedretti, R.; Bassett, P.; Wang, L.; Lemoff, A.; Villalon, L.; Kluve-Beckerman, B.; Saelices Gomez, L.
10.1101/2024.05.14.594028 — biophysics — Posted on 2024-05-14
2723 Reconstructing parent genomes using siblings and other relatives
Qiao, Y.; Jewett, E. M.; McManus, K. F.; Freyman, W. A.; Curran, J. E.; Williams-Blangero, S.; Blangero, J.; The 23andMe Research Team, ; Williams, A. L.
10.1101/2024.05.10.593578 — bioinformatics — Posted on 2024-05-14
2725 Spatial Coherence of DNA Barcode Networks
Bonet, D. F.; Blumenthal, J. I.; Lang, S.; Dahlberg, S. K.; Hoffecker, I. T.
10.1101/2024.05.12.593725 — bioinformatics — Posted on 2024-05-14
2727 IFDlong: an isoform and fusion detector for accurate annotation and quantification of long-read RNA-seq data
Wang, W.; Li, Y.; Ko, S.; Feng, N.; Zhang, M.; Liu, J.-J.; Zheng, S.; Ren, B.; Yu, Y.; Luo, J.-H.; Tseng, G. C.; Liu, S.
10.1101/2024.05.11.593690 — bioinformatics — Posted on 2024-05-14
2728 Cross-domain information fusion for enhanced cell population delineation in single-cell spatial-omics data
Zhu, B.; Gao, S.; Chen, S.; Yeung, J.; Bai, Y.; Huang, A.; Yeo, Y. Y.; Liao, G.; Mao, S.; Jiang, Z.; Rodig, S.; Shalek, A. K.; Nolan, G. P.; Jiang, S.; Ma, Z.
10.1101/2024.05.12.593710 — bioinformatics — Posted on 2024-05-14
2729 HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY
Viola, H.; Chen, L. H.; Jo, S.; Washington, K.; Selva, C.; Li, A.; Feng, D.; Giacalone, V.; Stephenson, S.; Cottrill, K.; Mohammed, A.; Williams, E.; Qu, X.; Lam, W. A.; Ng, N. L.; Fitzpatrick, A.; Grunwell, J.; Tirouvanziam, R.; Takayama, S.
10.1101/2024.05.10.593624 — bioengineering — Posted on 2024-05-14
2730 Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
Phillip, J. M.; Kamat, P.; Macaluso, N.; Min, C.; Li, Y.; Agrawal, A.; Winston, A.; Pan, L.; Starich, B. M.; Stewert, T.; Wu, P.-H.; Fan, J.; Walston, J.
10.1101/2024.05.10.593637 — bioengineering — Posted on 2024-05-14
2731 Probing the effects of polysaccharide hydrogel composition on the viability and pro-angiogenic function of human adipose-derived stromal cells
Serack, F. E.; Fennell, K. A.; Iliopoulos, C.; Walker, J. T.; Ronald, J. A.; Amsden, B. G.; Hess, D. A.; Flynn, L. E.
10.1101/2024.05.10.593603 — bioengineering — Posted on 2024-05-14
2732 Ultrasound-actuated drug delivery with acoustic percolation switches
Abundo, M. P.; Tifrea, A. T.; Buss, M. T.; Barturen-Larrea, P.; Jin, Z.; Malounda, D.; Shapiro, M. G.
10.1101/2024.05.10.593654 — bioengineering — Posted on 2024-05-14
2733 Opto-chemogenetic inhibition of L-type CaV1 channels in neurons through a membrane-assisted molecular linkage
Geng, J.; Yang, Y.; Li, B.; Yu, Z.; Qiu, S.; Zhang, W.; Gao, S.; Liu, N.; Liu, Y.; Wang, B.; Fan, Y.; Xing, C.; Liu, X.
10.1101/2024.05.12.593655 — bioengineering — Posted on 2024-05-14
2739 Evolutionary history of the main extracellular matrix polysaccharides in brown algae
Mazeas, L.; Bouguerba-Collin, A.; Cock, J. M.; Denoeud, F.; Godfroy, O.; Brillet-Gueguen, L.; Barbeyron, T.; Lipinska, A. P.; Delage, L.; Corre, E.; Drula, E.; Henrissat, B.; Czjzek, M.; Terrapon, N.; Herve, C.
10.1101/2024.04.23.590721 — evolutionary biology — Posted on 2024-05-14
2741 Ferroptosis mediates the progression of hyperuricemic nephropathy by activating RAGE signaling
Wang, Q.; Xi, Y.; Zhao, H.; Xie, D.; Yu, L.; Yan, Y.; Chen, J.; Zhang, Q.; Liang, M.; Cheng, J.
10.1101/2024.05.11.593667 — ecology — Posted on 2024-05-14
2745 Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2
Bashore, F. M.; Min, S. M.; Chen, X.; Howell, S.; Rinderle, C. H.; Morel, G.; Silvaroli, J. A.; Wells, C. I.; Bunnell, B. A.; Drewry, D.; Pabla, N. S.; Ultanir, S. K.; Bullock, A. N.; Axtman, A. D.
10.1101/2024.05.12.593776 — cell biology — Posted on 2024-05-14
2748 Activation of PIEZO1 Inhibits Kidney Cystogenesis
Fan, Q.; Hadla, M.; Peterson, Z.; Nelson, G.; Ye, H.; Wang, X.; Mardirossian, J.-M.; Harris, P. C.; Alper, S. L.; Y.S., P.; Beyder, A.; Torres, V. E.; Chebib, F. T.
10.1101/2024.05.11.593717 — cell biology — Posted on 2024-05-14
2749 Phenotype and function of IL-10 producing NK cells in individuals with malaria experience.
McNitt, S. A.; Dick, J. K.; Hernandez Castaneda, M.; Sangala, J. A.; Pierson, M.; Macchietto, M.; Burrack, K. S.; Crompton, P. D.; Seydel, K. B.; Hamilton, S. E.; Hart, G. T.
10.1101/2024.05.11.593687 — immunology — Posted on 2024-05-14
2751 Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease
West, P.; VanPortfliet, J. J.; Lei, Y.; Martinez, C. G.; Wong, J.; Pflug, K.; Sitcheran, R.; Kneeland, S.; Murray, S.; McGuire, P.; Cannon, C.
10.1101/2024.05.11.593693 — immunology — Posted on 2024-05-14
2752 Circulating PD-1hi CXCR5- and CXCR5+ CD4 T cells are elevated in patients with newly diagnosed Giant Cell Arteritis and predict relapse
Monjo-Henry, I.; Nieto-Carvalhal, B.; Uyaguari, M.; Garcia-Carazo, S.; Balsa, A.; de Miguel, E.; Miranda-Carus, M.-E.
10.1101/2024.05.12.593745 — immunology — Posted on 2024-05-14
2753 Automated and closed clinical-grade manufacturing protocol produces potent NK cells against neuroblastoma cells and AML blasts
Jahan, F.; Penna, L.; Luostarinen, A.; Veltman, L.; Hongisto, H.; Lähteenmäki, K.; Müller, S.; Ylä-Herttuala, S.; Korhonen, M.; Vettenranta, K.; Laitinen, A.; Salmenniemi, U.; Kerkelä, E.
10.1101/2024.05.12.593780 — immunology — Posted on 2024-05-14
2757 Individual connectivity-based parcellations reflect functional properties of human auditory cortex
Hakonen, M.; Dahmani, L.; Lankinen, K.; Ren, J.; Barbaro, J.; Blazejewska, A.; Cui, W.; Kotlarz, P.; Li, M.; Polimeni, J.; Turpin, T.; Uluc, I.; Wang, D.; liu, h.; Ahveninen, J.
10.1101/2024.01.20.576475 — neuroscience — Posted on 2024-05-14
2759 Parallel feedback processing for voluntary control: knowledge of spinal feedback in motor cortex
Guang, H.; Nashed, J. Y.; Pruszynski, J. A.; Kalidindi, H. T.; Crevecoeur, F.; Cross, K. P.; Blohm, G.; Scott, S. H.
10.1101/2024.05.12.593756 — neuroscience — Posted on 2024-05-14
2760 Air pollution from biomass burning disrupts early adolescent cortical microarchitecture development
Bottenhorn, K. L.; Sukumaran, K.; Cardenas-Iniguez, C.; Habre, R.; Schwartz, J.; Chen, J.-C.; Herting, M.
10.1101/2023.10.21.563430 — neuroscience — Posted on 2024-05-14
2763 LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK
Filipowska, J.; Cisneros, Z.; Leon-Rivera, N.; Wang, P.; Kang, R.; Lu, G.; Yuan, Y.-C.; Bhattacharya, S.; Dhawan, S.; Garcia-Ocana, A.; Kondegowda, N. G.; Vasavada, R. C.
10.1101/2024.05.10.593645 — physiology — Posted on 2024-05-14
2764 An integrated picture of the structural pathways controlling the heart performance
Lombardi, V.; Morotti, I.; Caremani, M.; Marcello, M.; Pertici, I.; Bianco, P.; Theyencheri, N.; Piazzesi, G.; Reconditi, M.; Linari, M.
10.1101/2024.05.11.593706 — physiology — Posted on 2024-05-14
2765 Sex-dependent adipose glucose partitioning by the mitochondrial pyruvate carrier
Shannon, C. E.; Bakewell, T.; Fourcaudot, M. J.; Ayala, I.; Romero, G.; Asmis, M.; Freitas Lima, L. C.; Wallace, M.; Norton, L.
10.1101/2024.05.11.593540 — physiology — Posted on 2024-05-14
2766 HYL001, a new potent TGFβ signaling inhibitor that is efficacious against microsatellite stable CRC metastasis in combination with immune checkpoint therapy in mice
Tauriello, D. V. F.; Sancho, E.; Byrom, D.; Sanchez-Zarzalejo, C.; Salvany, M.; Henriques, A.; Palomo-Ponce, S.; Sevillano, M.; Hernando-Momblona, X.; Matarin, J. A.; Ramos, I.; Ruano, I.; Prats, N.; Batlle, E.; Riera, A.
10.1101/2024.05.10.593510 — pharmacology and toxicology — Posted on 2024-05-14
2767 3D chromatin maps of a brown alga reveal U/V sex chromosome spatial organisation
Liu, P.; Vigneau, J.; Craig, R.; Barrera-Redondo, J.; Avdievich, E.; Martinho, C.; Borg, M.; Haas, F. B.; Liu, C.; Coelho, S. M.
10.1101/2024.05.11.593484 — genomics — Posted on 2024-05-14
2768 ZW sex chromosome structure in Amborella trichopoda
Carey, S. B.; Akozbek, L.; Lovell, J. T.; Jenkins, J. W.; Healey, A. L.; Shu, S.; Grabowsk, P.; Yocca, A.; Stewart, A.; Jones, T.; Barry, K. W.; Rajasekar, S.; Talag, J.; Scutt, C.; Lowry, P. P.; Munzinger, J.; Knox, E. B.; Soltis, D. E.; Soltis, P. S.; Grimwood, J.; Schmutz, J.; Leebens-Mack, J.; Harkess, A.
10.1101/2024.05.10.593579 — genomics — Posted on 2024-05-14
2769 Personalized transcriptome signatures in a cardiomyopathy stem cell biobank
Monte, E.; Furihata, T.; Wang, G.; Perea-Gil, I.; Wei, E.; Chaib, H.; Nair, R.; Guevara, J. V.; Mares, R.; Cheng, X.; Zhuge, Y.; Black, K.; Serrano, R.; Dagan-Rosenfeld, O.; Maguire, P.; Mercola, M.; Karakikes, I.; Wu, J. C.; Snyder, M. P.
10.1101/2024.05.10.593618 — genomics — Posted on 2024-05-14
2775 Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses
Turpin, R.; Peltonen, K.; Rannikko, J. H.; Liu, R.; Kumari, A. N.; Nicorici, D.; Lee, M. H.; Mutka, M.; Kovanen, P. E.; Niinikoski, L.; Meretoja, T.; Mattson, J.; Järvinen, P.; Lahdensuo, K.; Järvinen, R.; Tornberg, S.; Mirtti, T. J.; Boström, P.; Koskivuo, I.; Thotakura, A.; Pouwels, J.; Hollmen, M.; Mustjoki, S.; Klefström, J.
10.1101/2024.05.11.593502 — immunology — Posted on 2024-05-14
2776 Decoding Musical Valence And Arousal: Exploring The Neural Correlates Of Music Evoked Emotions And The Role Of Expressivity Features
Sayal, A.; Guedes, A. G.; Almeida, I.; Pereira, D. J.; Lima, C.; Panda, R.; Paiva, R. P.; Sousa, T.; Castelo-Branco, M.; Bernardino, I.; Direito, B.
10.1101/2024.02.27.582309 — neuroscience — Posted on 2024-05-14
2780 Pulsed sounds caused by internal oxygen transport during photosynthesis in the seagrass Halophila ovalis
Mok, H.-K.; Chang, Y.-W.; Fine, M. L.; Soong, K.; Chen, Y.-Y.; Gilmore, R. G.; Chiu, L. Y.-S.; Hsu, S.-L.; Chang, H.-J.
10.1101/2024.05.14.594143 — plant biology — Posted on 2024-05-14
2784 Inferred Developmental Origins of Brain Tumors from Single Cell RNA-Sequencing Data
Wang, S.; Curry, R. N.; Erickson, A. W.; Kleinman, C.; Taylor, M. D.; Rao, G.; Deneen, B.; Harmanci, A. O.; Serin Harmanci, A.
10.1101/2024.05.10.593553 — bioinformatics — Posted on 2024-05-14
2785 BIMSA: Accelerating Long Sequence Alignment Using Processing-In-Memory
Alonso-Marin, A.; Fernandez, I.; Aguado-Puig, Q.; Gomez-Luna, J.; Marco-Sola, S.; Moreto, M.
10.1101/2024.05.10.593513 — bioinformatics — Posted on 2024-05-14
2787 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging
Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.
10.1101/2023.10.30.564754 — bioengineering — Posted on 2024-05-14
2788 Rapid, high-resolution, non-destructive assessments of metabolic and morphological homogeneity uniquely identify high-grade cervical precancerous lesions
Polleys, C. M.; Singh, P.; Thieu, H.-T.; Genega, E. M.; Jahanseir, N.; Zuckerman, A. L.; Rius Diaz, F.; Patra, A.; Beheshti, A.; Georgakoudi, I.
10.1101/2024.05.10.593564 — bioengineering — Posted on 2024-05-14
2790 HIV-1 infection reduces NAD capping of host cell snRNA and snoRNA
Benoni, B.; Potuznik, J. F.; Skriba, A.; Benoni, R.; Trylcova, J.; Tulpa, M.; Spustova, K.; Grab, K.; Mititelu, M.-B.; Paces, J.; Weber, J.; Stanek, D.; Kowalska, J.; Bednarova, L.; Keckesova, Z.; Vopalensky, P.; Gahurova, L.; Cahova, H.
10.1101/2022.11.10.515957 — biochemistry — Posted on 2024-05-14
2792 Complex structural variation and behavioral interactions underpin a balanced sexual mimicry polymorphism
Dodge, T. O.; Kim, B. Y.; Baczenas, J. J.; Banerjee, S. M.; Gunn, T. R.; Donny, A. E.; Given, L. A.; Rice, A. R.; Haase Cox, S. K.; Weinstein, M. L.; Cross, R.; Moran, B. M.; Haber, K.; Haghani, N. B.; Machin Kairuz, J. A.; Gellert, H. R.; Du, K.; Aguillon, S. M.; Tudor, M. S.; Gutierrez-Rodriguez, C.; Rios-Cardenas, O.; Morris, M. R.; Schartl, M.; Powell, D. L.; Schumer, M.
10.1101/2024.05.13.594052 — evolutionary biology — Posted on 2024-05-14
2796 RosetteArray Platform for Quantitative High-Throughput Screening of Human Neurodevelopmental Risk
Lundin, B. F.; Knight, G. T.; Fedorchak, N. J.; Krucki, K.; Iyer, N.; Maher, J. E.; Izban, N. R.; Roberts, A.; Cicero, M. R.; Robinson, J. F.; Iskandar, B. J.; Willett, R.; Ashton, R. S.
10.1101/2024.04.01.587605 — neuroscience — Posted on 2024-05-14
2802 ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function
Dicenta-Baunach, V.; Laspa, Z.; Schaale, D.; Sigle, M.; Bayrak, A.; Castor, T.; Pillaiyar, T.; Laufer, S.; Gawaz, M. P.; Rohlfing, A.-K.
10.1101/2024.05.10.593491 — physiology — Posted on 2024-05-14
2806 Varroa mites escape the evolutionary trap of haplodiploidy
Eliash, N.; Tetsuya, E.; Johnston, S. J.; TECHER, M. A.; Holmes, V. R.; Rangel, J.; Economo, E. P.; Mikheyev, A. S.
10.1101/2024.05.10.593493 — evolutionary biology — Posted on 2024-05-14
2807 Stiffness-dependent LOX regulation via HIF-1 drives extracellular matrix modifications in psoriasis
Balsini, P.; Weinzettl, P.; Samardzic, D.; Zila, N.; Buchberger, M.; Tschandl, P.; Wielscher, M.; Weninger, W.; Pfisterer, K.
10.1101/2024.05.14.594058 — cell biology — Posted on 2024-05-14
2809 Unravelling the Impact of miR-21 Overexpression on the MicroRNA Network and Cancer Pathways
Hill, M.; Stapleton, S.; Nguyen, P. T.; Sais, D.; Deutsch, F.; Gay, V.; Marsh, D.; Tran, N.
10.1101/2024.05.10.593469 — cell biology — Posted on 2024-05-14
2813 Single-molecule digital sizing of proteins in solution
Krainer, G.; Jacquat, R. P. B.; Schneider, M. M.; Welsh, T. J.; Fan, J.; Peter, Q. A. E.; Andrzejewska, E. A.; Sneideriene, G.; Czekalska, M. A.; Ausserwoeger, H.; Chai, L.; Arter, W. E.; Saar, K. L.; Herling, T. W.; Franzmann, T. M.; Kosmoliaptsis, V.; Alberti, S.; Hartl, F.-U.; Lee, S. F.; Knowles, T. P. J.
10.1101/2023.07.12.548675 — biophysics — Posted on 2024-05-14
2817 Optimizing clinical interpretability of functional evidence in epilepsy-related ion channel variants
Parthasarathy, S.; Cohen, S. R.; Fitch, E.; Vaidiswaran, P.; Ruggiero, S. M.; Lusk, L.; Chisari, V.; Lewis-Smith, D.; Lauxmann, S.; Bosselmann, C. M.; Thompson, C. H.; Wengert, E. R.; Hedrich, U.; Ganesan, S.; Balagura, G.; Krause, R.; Xian, J.; Galer, P. D.; Pendziwiat, M.; Perez-Palma, E.; Vihinen, M.; Hart, J.; Landrum, M. J.; Lal, D.; Cooper, E. C.; Lerche, H.; Goldberg, E. M.; Brunklaus, A.; Vanoye, C. G.; Schorge, S.; George, A. L.; Helbig, I.
10.1101/2024.05.09.593343 — genetics — Posted on 2024-05-14
2818 Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators
Notario Manzano, R.; Chaze, T.; Rubinstein, E.; Penard, E.; Matondo, M.; Zurzolo, C.; Brou, C.
10.1101/2022.12.21.521537 — cell biology — Posted on 2024-05-14
2822 CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization
Serbynovskyi, V.; Wang, J.; Chua, E. Y. D.; Ishemgulova, A.; Alink, L. M.; Budell, W. C.; Johnston, J. D.; Dubbeldam, C.; Gonzalez, F. A.; Rozovsky, S.; Eng, E. T.; de Marco, A.; Noble, A. J.
10.1101/2024.01.23.576763 — molecular biology — Posted on 2024-05-14
2823 Single-cell and spatial atlas of steatotic liver-related hepatocellular carcinoma
Prawira, A.; Xu, H.; Leow, W. Q.; Otsuka, M.; Chen, Z.; Rahbari, M.; Hazirah, S. N.; Wasser, M.; Chung, A.; Goh, B. K. P.; Chow, P. K.-H.; Albani, S.; Lee, J.; Lim, T.; Zhai, W.; Dan, Y. Y.; Goh, G.; Tai, D.; DasGupta, R.; Heikenwalder, M.; Chen, J.; Chew, V.
10.1101/2024.05.09.593073 — immunology — Posted on 2024-05-14
2827 Disentangling plant response to biotic and abiotic stress using HIVE, a novel tool to perform unpaired multi-transcriptomics integration
Calia, G.; Marguerit, S.; Zotta Mota, A. P.; Vidal, M.; Seynabou, M.; Nguyen, H. T.; Ghat, A.; Schuler, H.; Gwizdek, C.; Brasileiro, A.; Guimares, P.; Bottini, S.
10.1101/2024.03.04.583290 — plant biology — Posted on 2024-05-14
2829 Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
Urbauer, E.; Aguanno, D.; Mindermann, N.; Omer, H.; Metwaly, A.; Krammel, T.; Faro, T.; Remke, M.; Reitmeier, S.; Bärthel, S.; Kersting, J.; Huang, Z.; Xian, F.; Schmidt, M.; Saur, D.; Huber, S.; Stecher, B.; List, M.; Gomez-Varela, D.; Steiger, K.; Allez, M.; Rath, E.; Haller, D.
10.1101/2023.07.27.549844 — microbiology — Posted on 2024-05-14
2830 Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression
Tcyganov, E. N.; Kwak, T.; Yang, X.; Poli, A. N. R.; Hart, C.; Bhuniya, A.; Cassel, J.; Kossenkov, A.; Auslander, N.; Lu, L.; Sharma, P.; Mendoza, M. D. G. C.; Zhigarev, D.; Cadungog, M. G.; Jean, S.; Chatterjee-Paer, S.; Weiner, D. B.; Donthireddy, L.; Bristow, B.; Zhang, R.; Tyurin, V. A.; Tyurina, Y. Y.; Bayir, H.; Kagan, V. E.; Salvino, J. M.; Montaner, L. J.
10.1101/2024.05.10.593562 — immunology — Posted on 2024-05-14
2831 Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior
Flerlage, W. J.; Simmons, S. C.; Thomas, E. H.; Gouty, S.; Tsuda, M. C.; Wu, T. J.; Armstrong, R. S.; Cox, B. M.; Nugent, F. S.
10.1101/2024.04.16.589760 — neuroscience — Posted on 2024-05-14
2834 Androgen receptor activity inversely correlates with immune cell infiltration and immunotherapy response across multiple cancer lineages
Hu, Y.-M.; Zhao, F.; Graff, J.; Chen, C.; Zhao, X.; Thomas, G. V.; Wu, H.; Kardosh, A.; Mills, G.; Alumkal, J.; Moran, A. E.; Xia, Z.
10.1101/2024.05.08.593181 — cancer biology — Posted on 2024-05-14
2835 Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid.
Pan, M.; Zhang, Y.; Wright, W. C.; Liu, X.; Passaia, B.; Currier, D.; Chapple, R. H.; Steele, J.; Connelly, J. P.; Lu, M.; Lee, H.-M.; Loughran, A.; Yang, L.; Abraham, B. J.; Pruett-Miller, S. M.; Freeman, B.; Campbell, G. E.; Dyer, M. A.; Chen, T.; Stewart, E.; Koo, S.; Sheppard, H.; Easton, J.; Geeleher, P.
10.1101/2024.05.09.593394 — cancer biology — Posted on 2024-05-14
2837 Longitudinal Prediction of Drug Response in High-Grade Serous Ovarian Cancer Organoid Cultures Aligning with Clinical Responses
Cavarzerani, E.; Caligiuri, I.; Bartoletti, M.; Corona, G.; Perin, T.; Palumbo, A.; Canzonieri, V.; Rizzolio, F.
10.1101/2024.05.09.593311 — cancer biology — Posted on 2024-05-14
2838 Empowering bioinformatics communities with Nextflow and nf-core
Langer, B. E.; Amaral, A.; Baudement, M.-O.; Bonath, F.; Charles, M.; Chitneedi, P. K.; Clark, E. L.; Di Tommaso, P.; Djebali, S.; Ewels, P. A.; Eynard, S.; Fellows Yates, J. A.; Fischer, D.; Floden, E. W.; Foissac, S.; Gabernet, G.; Garcia, M. U.; Gillard, G.; Gundappa, M. K.; Guyomar, C.; Hakkaart, C.; Hanssen, F.; Harrison, P. W.; Hortenhuber, M.; Kurylo, C.; Kuhn, C.; Lagarrigue, S.; Lallias, D.; Macqueen, D. J.; Miller, E.; Mir-Pedrol, J.; Moreira, G. C. M.; Nahnsen, S.; Patel, H.; Peltzer, A.; Pitel, F.; Ramayo-Caldas, Y.; Ribeiro-Dantas, M. d. C.; Rocha, D.; Salavati, M.; Sokolov, A.; E
10.1101/2024.05.10.592912 — bioinformatics — Posted on 2024-05-14
2841 Robust analysis of allele-specific copy number alterations from scRNA-seq data with XClone
Huang, R.; Huang, X.; Tong, Y.; Yan, H. Y. N.; Leung, S. Y.; Stegle, O.; Huang, Y.
10.1101/2023.04.03.535352 — bioinformatics — Posted on 2024-05-14
2842 Quick-quick-slow: the foxtrot migration and dynamic non-breeding range of the Arctic raptor
Pokrovsky, I.; Curk, T.; Dietz, A.; Fufachev, I.; Kulikova, O.; Rossler, S.; Wikelski, M.
10.1101/2023.03.13.532370 — ecology — Posted on 2024-05-14
2845 Associations between methylation age and brain age in late adolescence
Sanders, F.; Baltramonaityte, V.; Donohoe, G.; Davies, N. M.; Dunn, E. C.; Cecil, C. A. M.; Walton, E.
10.1101/2022.09.08.506972 — neuroscience — Posted on 2024-05-14
2846 Oviposition and vertical dispersal of Aedes species Meigen 1818 (Diptera: Culicidae) at different heights and seasonal periods in an urban forest fragment in Manaus, Amazonas, Brazil
Ribeiro da Silva, W.; Arcos, A. N.; da Silva Ferreira, F. A.; Soares-da-Silva, J.; Pontes, G. O.; Navarro-Silva, M. A.; Roque, R. A.; ZEQUI, J. A. C.
10.1101/2024.05.09.593399 — zoology — Posted on 2024-05-14
2849 Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profiles
He, S.; Mohanty, V.; Gubin, M. M.; Rafei, H.; Basar, R.; Dede, M.; Jiang, X.; Liang, Q.; Tan, Y.; Kim, K.; Gillison, M. L.; Rezvani, K.; Peng, W.; Haymaker, C.; Hernandex, S.; Solis, L. M.; Chen, K.
10.1101/2024.05.10.593433 — bioinformatics — Posted on 2024-05-14
2850 LucaOne: Generalized Biological Foundation Model with Unified Nucleic Acid and Protein Language
He, Y.; Fang, P.; Shan, Y.; Pan, Y.; Wei, Y.; Chen, Y.; Chen, Y.; Liu, Y.; Zeng, Z.; Zhou, Z.; Zhu, F.; Holmes, E. C.; Ye, J.; Li, J.; Shu, Y.; Shi, M.; Li, Z.
10.1101/2024.05.10.592927 — bioinformatics — Posted on 2024-05-14
2851 H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation
Fox, G. C.; Poncha, K. F.; Smith, B. R.; van der Maas, L. N.; Robbins, N. N.; Graham, B.; Dowen, J. M.; Strahl, B. D.; Young, N. L.; Jain, K.
10.1101/2024.05.13.590588 — biochemistry — Posted on 2024-05-14
2852 Proteasome regulation of petite-negativity in fission yeast
Amberg, K. L.; Hao, L.; Cranz-Mileva, S.; Zaratiegui, M.
10.1101/2024.05.09.593392 — genetics — Posted on 2024-05-14
2853 G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics
Mazharian, A.; Bertin, O.; Sarkar, A.; Augros, J.; Bornert, A.; Loubiere, C.; Jönsson, F.; Warwicker, J.; Abbott, W. M.; Dushek, O.; Vayne, C.; Rauova, L.; Fütterer, K.; Rollin, J.; Poncz, M.; Senis, Y. A.
10.1101/2024.05.10.593500 — cell biology — Posted on 2024-05-14
2854 miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses
Pinto-Hernandez, P.; Fernandez-Sanjurjo, M.; Paget, D.; Caravia, X. M.; Roiz-Valle, D.; Castilla-Silgado, J.; Diez-Robles, S.; Coto-Vilcapoma, A.; Gama, P.; Garcia-Roves, P. M.; Lopez-Otin, C.; Zierath, J. R.; Krook, A.; Fernandez-Garcia, B.; Tomas-Zapico, C.; Iglesias-Gutierrez, E.
10.1101/2024.05.14.592416 — molecular biology — Posted on 2024-05-14
2855 Control of Inflammatory Response by Tissue Microenvironment
Wu, Z.; Pope, S. D.; Ahmed, N. S.; Leung, D. L.; Hajjar, S.; Yue, Q.; Anand, D. M.; Kopp, E. B.; Okin, D.; Ma, W.; Kagan, J. C.; Hargreaves, D. C.; Medzhitov, R.; Zhou, X.
10.1101/2024.05.10.592432 — immunology — Posted on 2024-05-14
2856 Structural basis of autoantibody binding in Neuromyelitis Optica
Gupta, M.; Khandelwal, N. K.; Nelson, A.; Hwang, P.; Pourmal, S.; Bennett, J. L.; Stroud, R. M.
10.1101/2024.05.12.592631 — immunology — Posted on 2024-05-14
2857 ILC2s navigate tissue redistribution during infection using stage-specific S1P receptors
Ito, T.; Ishida, Y.; Zhang, Y.; Guichard, V.; Zhang, W.; Han, R. P.; Guckian, K.; Chun, J.; Que, J.; Smith, A.; Urban, J. F.; Huang, Y.
10.1101/2024.05.12.592576 — immunology — Posted on 2024-05-14
2858 Effects of context changes on memory reactivation
Ozdemir, S.; Senturk, Y. D.; Unver, N.; Demircan, C.; Olivers, C. N. L.; Egner, T.; Gunseli, E.
10.1101/2024.03.20.585920 — neuroscience — Posted on 2024-05-14
2859 Revealing non-trivial information structures in aneural biological tissues via functional connectivity
Blackiston, D.; Dromiack, H.; Grasso, C.; Varley, T. F.; Moore, D. G.; Srinivasan, K.; Sporns, O.; Bongard, J.; Levin, M.; Walker, S. I.
10.1101/2024.05.09.593467 — systems biology — Posted on 2024-05-14
2862 Population origin, body mass, and viral infections influence drone honey bee (Apis mellifera) heat tolerance
McAfee, A.; Metz, B. N.; Connor, P.; Du, K.; Allen, C. W.; Frausto, L. A.; Swensen, M. P.; Phillips, K. S.; Julien, M.; Baer, B.; Tarpy, D. R.; Foster, L. J.
10.1101/2024.05.12.593456 — physiology — Posted on 2024-05-14
2863 Design, synthesis and cellular characterization of a new class of IPMK kinase inhibitors
Zhou, Y.; Chapagain, P.; Desmarini, D.; Uredi, D.; Rameh Plant, L. E.; Djordjevic, J. T.; Blind, R. D.; Wang, X.
10.1101/2024.05.09.593371 — pharmacology and toxicology — Posted on 2024-05-14
2865 Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets
Nicholson, T. M.; Tokihiro, J. C.; Tu, W.-c.; Khor, J. W.; Lee, U. N.; Berthier, E.; Amory, J. K.; Walsh, T. J.; Muller, C. H.; Theberge, A. B.
10.1101/2024.05.09.593416 — bioengineering — Posted on 2024-05-14
2866 Assessing the Impact of Valve Sizing and Orientation on Bioprosthetic Pulmonary Valve Hemodynamics Using In Vitro 4D-Flow MRI
Schaivone, N. K.; Nair, P. J.; Elkins, C. J.; McElhinney, D. B.; Ennis, D. B.; Eaton, J. K.; Marsden, A. L.
10.1101/2024.05.09.593439 — bioengineering — Posted on 2024-05-14
2868 A large pocket structure surrounding the catalytic center in the BCG protein from Mycobacterium tuberculosis
Takeshita, K.; Sakai, N.; Ueno, G.; Horie, M.; Tsujino, H.; Arisawa, M.; Yamamoto, M.; Arai, M.; Yamashita, T.
10.1101/2024.05.14.591795 — biochemistry — Posted on 2024-05-14
2869 Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII.4 and GII.17
Tagawa, J.; Yanaka, S.; Kato, Y.; Masuda, A.; Lee, J. M.; Senoo, A.; Oyama, K.; Nishida, M.; Kusakabe, T.; Caaveiro, J. M. M.
10.1101/2024.05.11.593658 — biochemistry — Posted on 2024-05-14
2870 Three-dimensional aortic geometry: clinical correlates, prognostic value and genetic architecture
Beeche, C.; Dib, M.-J.; Zhao, B.; Azzo, J.-D.; Maynard, H.; Duda, J.; Gee, J.; Salman, O.; Witschey, W.; Chirinos, J.
10.1101/2024.05.09.593413 — genomics — Posted on 2024-05-14
2871 Conservation of Regulatory Elements with Highly Diverged Sequences Across Large Evolutionary Distances
Phan, M. H.; Zehnder, T. M.; Puntieri, F.; Lo, B.-W.; Lenhard, B.; Mueller, F.; Vingron, M.; Ibrahim, D. M.
10.1101/2024.05.13.590087 — genetics — Posted on 2024-05-14
2872 Two retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity
Wood, T. W. P.; Henriques, W. S.; Cullen, H. B.; Romero, M.; Blengini, C. S.; Sarathy, S.; Sorkin, J.; Bekele, H.; Jin, C.; Kim, S.; Chemiakine, A.; Khondker, R.; Isola, J. V. V.; Stout, M.; Gennarino, V. A.; Mogessie, B.; Jain, D.; Schindler, K.; Suh, Y.; Wiedenheft, B.; Berchowitz, L. E.
10.1101/2024.05.11.592987 — genetics — Posted on 2024-05-14
2873 GENE THERAPY PREVENTS HEPATIC MITOCHONDRIAL DYSFUNCTION IN MURINE DEOXYGUANOSINE KINASE DEFICIENCY
Keshavan, N.; Greenwood, M.; Prunty, H.; Antinao Diaz, J. F.; Privolizzi, R.; Counsell, J.; Karlsson, A.; Waddington, S.; Karda, R.; Rahman, S.
10.1101/2024.05.10.593325 — genetics — Posted on 2024-05-14
2876 Acceleration of genome rearrangement in clitellate annelids
Schultz, D. T.; Heath-Heckman, E. A. C.; Winchell, C. J.; Kuo, D.-H. T.; Yu, Y.-s.; Oberauer, F.; Kocot, K.; Cho, S.-J.; Simakov, O.; Weisblat, D. A.
10.1101/2024.05.12.593736 — evolutionary biology — Posted on 2024-05-14
2877 Keys to the cabinet: unlocking biodiversity data in public entomology collections
Gibson, J. F.; Howse, M.; Paillard, C.; Penfold, C.; Penno, A.; van der Voort, G. E.; Huber, D. P. W.
10.1101/2024.05.10.593424 — ecology — Posted on 2024-05-14
2879 Biomechanical regulation of cell shapes promotes branching morphogenesis of the ureteric bud epithelium
Kurtzeborn, K.; Iaroshenko, V.; Zarybnicky, T.; Koivula, J.; Anttonen, H. S.; Bridgewater, D.; Krishnan, R.; Chen, P.; Kuure, S.
10.1101/2024.03.28.585666 — developmental biology — Posted on 2024-05-14
2881 Tendon-associated gene expression precedes osteogenesis in mid-palatal suture establishment
Roth, D. M.; Oliver Pina, J.; Raju, R.; Iben, J. R.; Faucz, F. R.; Makareeva, E.; Leikin, S.; Graf, D.; D'Souza, R. N.
10.1101/2024.05.11.590129 — developmental biology — Posted on 2024-05-14
2884 Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells
Matson, A. W.; Hullsiek, R. H.; Dixon, K. J.; Lindstedt, A. J.; Friess, R. R.; Phung, S. K.; Freedman, T. S.; Felices, M.; Truckenbrod, E. N.; Wu, J.; Miller, J.; Walcheck, B.
10.1101/2024.05.09.593347 — immunology — Posted on 2024-05-14
2885 Sexually dimorphic regulatory T cell-derived enkephalin imparts pregnancy-induced analgesia
Midavaine, E.; Moraes, B. C.; Benitez, J.; Rodriguez, S. R.; Braz, J. M.; Kochhar, N. P.; Eckalbar, W. L.; Domingos, A. I.; Pintar, J. E.; Basbaum, A. I.; Kashem, S. W.
10.1101/2024.05.11.593442 — immunology — Posted on 2024-05-14
2886 Rapid metabolic regulation of a novel arginine methylation of KCa3.1 attenuates T cell exhaustion.
Sharma, P.; Guo, A.; Boada Romero, E.; Poudel, S.; Verbist, K. C.; Palacios, G.; Immadisetty, K.; Chen, M. J.; Haydar, D.; Mishra, A.; Peng, J.; Babu, M. M.; Krenciute, G.; Glazer, E. S.; Green, D. R.
10.1101/2024.05.09.593421 — immunology — Posted on 2024-05-14
2887 Pro-inflammatory macrophage activation does not require inhibition of mitochondrial respiration
Ball, A. B.; Jones, A. E.; Nguyen, K. B.; Rios, A.; Marx, N.; Hsieh, W. Y.; Yang, K.; Desousa, B. R.; Kim, K. K. O.; Veliova, M.; del Mundo, Z. M.; Shirihai, O. S.; Beninca, C.; Stiles, L.; Bensinger, S. J.; Divakaruni, A. S.
10.1101/2024.05.10.593451 — immunology — Posted on 2024-05-14
2889 Decoding region-level visual functions from invasive EEG data
Zhang, X.-Y.; Lin, H.; Deng, Z.; Siegel, M.; Miller, E. K.; Yan, G.
10.1101/2024.04.02.587853 — neuroscience — Posted on 2024-05-14
2890 Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism
Dierks, D.; Nir, R.; Shachar, R.; Uzonyi, A.; Garcia-Campos, M. A.; Rossmanith, W.; Hanna, J. H.; Slobodin, B.; Antebi, Y.; Scherz-Shouval, R.; Schwartz, S.
10.1101/2024.05.09.593376 — systems biology — Posted on 2024-05-14
2891 Advancing chloroplast synthetic biology through high-throughput plastome engineering of Chlamydomonas reinhardtii
Inckemann, R.; Chotel, T.; Brinkmann, C. K.; Burgis, M.; Andreas, L.; Baumann, J.; Sharma, P.; Klose, M.; Barrett, J.; Ries, F.; Paczia, N.; Glatter, T.; Mackinder, L.; Willmund, F.; Erb, T. J.
10.1101/2024.05.08.593163 — synthetic biology — Posted on 2024-05-14
2893 Immunosuppression in the prostate tumor microenvironment is tied to androgen deprivation therapy-resistant club-like cells
Kiviaho, A.; Eerola, S. K.; Kallio, H. M. L.; Andersen, M. K.; Spotbeen, X.; Giesen, A.; Parker, C. T. A.; Taavitsainen, S.; Hantula, O.; Marttinen, M.; Hermelo, I.; Ismail, M.; Midtbust, E.; Wess, M.; Devlies, W.; Sharma, A.; Krossa, S.; Hakkinen, T.; Afyounian, E.; Kesseli, J.; Tolonen, T.; Tammela, T. L. J.; Viset, T.; Storkersen, O.; Giskeodegord, G. F.; Rye, M. B.; Murtola, T.; Erickson, A.; Latonen, L.; Bova, G. S.; Mills, I. G.; Joniau, S.; Swinnen, J. V.; Voet, T.; Mirtti, T.; Attard, G.; Claessens, F.; Visakorpi, T.; Rautajoki, K. J.; Tessem, M.-B.; Urbanucci, A.; Nykter, M.
10.1101/2024.03.25.586330 — cancer biology — Posted on 2024-05-14
2894 Deciphering the molecular mechanism underlying morphology transition in two-component DNA-protein cophase separation
Li, C.; Bian, Y.; Tang, Y.; Meng, L.; Yin, P.; Hong, Y.; Cheng, J.; Li, Y.; Lin, J.; Tang, C.; Chen, C.; Li, W.; Qi, Z.
10.1101/2024.01.26.577305 — biophysics — Posted on 2024-05-14
2897 Metabolic rewiring in fat-depleted Drosophila reveals triglyceride:glycogen crosstalk and identifies cDIP as a new regulator of energy metabolism
Ugrankar-Banerjee, R.; Tran, S.; Bowerman, J.; Paul, B.; Zacharias, L. G.; Mathews, T. P.; DeBerardinis, R. J.; Henne, W. M.
10.1101/2024.05.13.593915 — cell biology — Posted on 2024-05-14
2898 Structure of the lens MP20 mediated adhesive junction
Nicolas, W. J.; Shiriaeva, A.; Martynowycz, M. W.; Grey, A. C.; Ruma, Y.; Donaldson, P. J.; Gonen, T.
10.1101/2024.05.13.594022 — biophysics — Posted on 2024-05-14
2899 Neandertal ancestry through time: Insights from genomes of ancient and present-day humans
Iasi, L. N. M.; Chintalapati, M.; Skov, L.; Bossoma Mesa, A.; Hajdinjak, M.; Peter, B. M.; Moorjani, P.
10.1101/2024.05.13.593955 — evolutionary biology — Posted on 2024-05-13
2902 Oxysterol accumulation in aging cells alters GPCR signalling
Asthana, S.; Verma, A.; Bhattacharya, B.; Nath, A.; Maan, K.; Sajeev, N.; Nair, R. R.; Saini, D. K.; Ayappa, K. G.
10.1101/2024.05.09.593443 — cell biology — Posted on 2024-05-14
2904 Deep Visual Proteomics advances human colon organoid models by revealing a switch to an in vivo-like phenotype upon xenotransplantation
Post, F.; Hausmann, A.; Kabatnik, S.; Steigerwald, S.; Brand, A.; Clement, D. L.; Skov, J.; Boye, T. L.; Sato, T.; Steenholdt, C.; Mund, A.; Nielsen, O. H.; Jensen, K. B.; Mann, M.
10.1101/2024.05.13.593888 — cell biology — Posted on 2024-05-14
2905 Epithelial NSD2 maintains FMOs-mediated taurine biosynthesis to prevent intestinal barrier disruption
Xu, Y.; Ma, C.; Wang, Z.; Feng, W.; Rao, H.; Zhang, W.; Liu, N.; Aji, R.; Meng, X.; Gao, W.-Q.; Li, L.
10.1101/2024.05.09.593261 — cell biology — Posted on 2024-05-14
2906 Specialized Pericyte Subtypes in the Pulmonary Capillary
Klouda, T.; Kim, Y.; Baek, S.-H.; Bhaumik, M.; Liu, Y.; Liu, T.; Que, J.; Wu, J. C.; Raby, B. A.; de Jesus Perez, V.; Yuan, K.
10.1101/2024.05.09.593174 — cell biology — Posted on 2024-05-14
2908 Supervised and unsupervised deep learning-based approaches for studying DNA replication spatiotemporal dynamics
Ng-Kee-Kwong, J.; Philps, B.; Smith, F. N. C.; Sobieska, A.; Chen, N.; Alabert, C.; Bilen, H.; Buonomo, S.
10.1101/2024.05.09.593366 — cell biology — Posted on 2024-05-14
2910 Reconstitution of Arp2/3-Nucleated Actin Assembly with CP, V-1 and CARMIL
Mooren, O. L.; McConnell, P.; DeBrecht, J. D.; Jaysingh, A.; Cooper, J. A.
10.1101/2024.05.13.593916 — cell biology — Posted on 2024-05-14
2911 In Utero Hematopoietic Stem Cell Transplant for Fanconi Anemia
Swartzrock, L.; Dib, C.; Denis, M.; Willner, H.; Ho, K.; Haslett, E.; Krampf, M. R.; Girsen, A.; Blumenfeld, Y. J.; El-Sayed, Y. Y.; Roncarolo, M. G.; MacKenzie, T. C.; Czechowicz, A. D.
10.1101/2024.05.09.592452 — cell biology — Posted on 2024-05-14
2914 Membrane potential mediates an ancient mechano-transduction mechanism for multi-cellular homeostasis
Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J. G.; Neliat, A. R.; Schuttler, J.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.
10.1101/2023.11.02.565386 — cell biology — Posted on 2024-05-13
2915 Related PP2C phosphatases Pic3 and Pic12 negatively regulate immunity in tomato to Pseudomonas syringae
Xia, F.; Zhang, N.; Smith, R. E.; Chakraborty, J.; Sobol, G.; Tang, X.; Fei, Z.; Sessa, G.; Martin, G. B.
10.1101/2024.02.08.579555 — plant biology — Posted on 2024-05-13
2917 Expanding and enriching the LncRNA gene-disease landscape using the GeneCaRNA database
Aggarwal, S.; Rosenblum, C.; Gould, M.; Ziman, S.; Barshir, R.; Zelig, O.; Golan, Y. G.; Iny-Stein, T.; Safran, M.; Pietrokovski, S.; Lancet, D.
10.1101/2024.03.11.584435 — bioinformatics — Posted on 2024-05-13
2919 Generative artificial intelligence performs rudimentary structural biology modeling
Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.
10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-05-13
2922 Human STING oligomer function is governed by palmitoylation of an evolutionarily conserved cysteine
Chan, R. J. M.; Cao, X.; Ergun, S. L.; Njomen, E.; Lynch, S. R.; Ritchie, C.; Cravatt, B. F.; Li, L.
10.1101/2023.08.11.553045 — biochemistry — Posted on 2024-05-13
2923 Placental Malaria Induces a Unique Placental Methylation Profile Associated with Fetal Growth Restriction
Ozarslan, N.; Mong, C.; Ategeka, J.; Li, L.; Buarpung, S.; Robinson, J. F.; Kizza, J.; Kakuru, A.; Kamya, M. R.; Dorsey, G.; Rosenthal, P. J.; Gaw, S. L.
10.1101/2024.05.09.593431 — genetics — Posted on 2024-05-13
2927 Soil microbial community response to corrinoids is shaped by a natural reservoir of vitamin B12.
Hallberg, Z. F.; Nicolas, A. M.; Alvarez-Aponte, Z. I.; Mok, K. C.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J.; Carlson, H. K.; Firestone, M. K.; Taga, M. E.
10.1101/2024.02.12.580003 — microbiology — Posted on 2024-05-13
2928 Genetic evidence for functional diversification of gram-negative intermembrane phospholipid transporters
Rai, A. K.; Sawasato, K.; Bennett, H. C.; Kozlova, A.; Sparagna, G. C.; Bogdanov, M.; Mitchell, A. M.
10.1101/2023.06.21.545913 — microbiology — Posted on 2024-05-13
2929 Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics
Liu, Y.; Yin, M.; Mao, X.; Wu, S.; Wei, S.; Heng, S.; Yang, Y.; Huang, J.; Guo, Z.; Li, C.; Ji, C.; Hu, L.; Liu, W.; Zhang, L.-j.
10.1101/2024.01.16.575925 — immunology — Posted on 2024-05-13
2930 Loss of circulating CD8α+ NK cells during human Mycobacterium tuberculosis infection
Mehanna, N.; Pradhan, A.; Kaur, R.; Kontopoulos, T.; Rosati, B.; Carlson, D.; Cheung, N.-K.; Xu, H.; Bean, J.; Hsu, K.; Le Luduec, J.-B.; Vorkas, C. K.
10.1101/2024.04.16.588542 — immunology — Posted on 2024-05-13
2931 FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling
Khan, M. S. H.; Kim, S. Q.; Ross, R. C.; Corpodean, F.; Spann, R. A.; Albarado, D. A.; Fernandez-Kim, S. O.; Clarke, B.; Berthoud, H.-R.; Münzberg, H.; McDougal, D. H.; He, Y.; Yu, S.; Albaugh, V. L.; Soto, P.; Morrison, C. D.
10.1101/2024.03.05.583399 — neuroscience — Posted on 2024-05-13
2932 Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation
Isbister, J. B.; Ecker, A.; Pokorny, C.; Bolanos-Puchet, S.; Egas Santander, D.; Arnaudon, A.; Awile, O.; Barros-Zulaica, N.; Blanco Alonso, J.; Boci, E.; Chindemi, G.; Courcol, J.-D.; Damart, T.; Delemontex, T.; Dietz, A.; Ficarelli, G.; Gevaert, M.; Herttuainen, J.; Ivaska, G.; Ji, W.; Keller, D.; King, J.; Kumbhar, P.; Lapere, S.; Litvak, P.; Mandge, D.; Muller, E. B.; Pereira, F.; Planas, J.; Ranjan, R.; Reva, M.; Romani, A.; Rössert, C.; Schürmann, F.; Sood, V.; Teska, A.; Tuncel, A.; Van Geit, W.; Wolf, M.; Markram, H.; Ramaswamy, S.; Reimann, M. W.
10.1101/2023.05.17.541168 — neuroscience — Posted on 2024-05-13
2937 Enhancing affinity of neutralizing SARS-CoV-2 nanobody through facile structure-guided mutations in CDRs
Singh, V.; Bhutkar, M.; Choudhary, S.; Nehul, S.; Kumar, R.; Singla, J.; Kumar, P.; Tomar, S.
10.1101/2024.05.13.593833 — bioengineering — Posted on 2024-05-13
2938 Unconstrained Precision Mitochondrial Genome Editing with αDdCBEs
Castillo, S. R.; Simone, B. W.; Clark, K. J.; Devaux, P.; Ekker, S. C.
10.1101/2024.05.13.593977 — bioengineering — Posted on 2024-05-13
2942 Differential roles of putative arginine fingers of AAA+ ATPases Rvb1 and Rvb2
Warnock, J. L.; Ball, J. A.; Najmi, S. M.; Henes, M.; Vazquez, A.; Koshnevis, S.; Wieden, H.-J.; Conn, G. L.; Ghalei, H.
10.1101/2024.05.13.593962 — biochemistry — Posted on 2024-05-13
2945 Pooled genetic screens identify breast cancer risk genes involved in evasion from T cell-mediated killing
Shi, W.; Luo, Y.; Burrows, J. M.; Black, D.; Civitarese, A.; Perlaza-Jimenez, L.; Ping, Z.; Manning, M.; Tuano, N.; Renteria, M. E.; Xiao, C.; Tey, S.-K.; Rosenbluh, J.; Smith, C.; Chenevix-Trench, G.; Beesley, J.
10.1101/2024.05.10.593465 — genetics — Posted on 2024-05-13
2946 Proteasomal control of anti-CRISPRs for the regulation of CRISPR/Cas9 activity using Cas9-ACROBAT
Martin, T. D.; Watson, E. V.; Choi, M. Y.; Nabet, B.; Gray, N. S.; Xu, Q.; Elledge, S.
10.1101/2024.05.13.593596 — cell biology — Posted on 2024-05-13
2947 BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains
Beigl, T. B.; Paul, A.; Fellmeth, T.; Nguyen, D.; Barber, L.; Weller, S.; Schaefer, B.; Gillissen, B. F.; Aulitzky, W. E.; Kopp, H.-G.; Rehm, M.; Andrews, D. W.; Pluhackova, K.; Essmann, F.
10.1101/2024.05.13.593225 — molecular biology — Posted on 2024-05-13
2950 Peroxiredoxin 2 Regulates DAF-16/FOXO Mediated Mitochondrial Remodelling in Response to Exercise that is Disrupted in Ageing
Xia, Q.; Li, P.; Casas-Martinez, J. C.; Miranda-Vizuete, A.; McDermott, E.; Dockery, P.; Goljanek-Whysall, K.; McDonagh, B.
10.1101/2024.05.13.593975 — molecular biology — Posted on 2024-05-13
2951 Persistent lung inflammation and alveolar-bronchiolization due to Notch signaling dysregulation in SARS-CoV-2 infected hamster
Li, C.; Xiao, N.; Song, W.; Lam, A. H.-C.; Liu, F.; Cui, X.; Ye, Z.; Chen, Y.; Ren, P.; Cai, J.; Lee, A. C.-Y.; Chen, H.; Ou, Z.; Chan, J. F.-W.; Yuen, K.-Y.; Chu, H.; Zhang, A. J.-X.
10.1101/2024.05.13.593878 — microbiology — Posted on 2024-05-13
2953 Commensal or pathogen: computational vectorizing microbial genomes for de novo risk assessment and virulence feature discovery in Klebsiella pneumoniae
Beck, K. L.; Agarwal, A.; Halpin, A. L.; McDonald, L. C.; McKay, S. L.; Kent, A. G.; Kaufman, J. H.; Mukherjee, V.; Elkins, C. A.; Seabolt, E.
10.1101/2024.05.13.593956 — microbiology — Posted on 2024-05-13
2955 Functional genomics reveals the mechanism of hypoxic adaptation in nontuberculous mycobacteria
Tateishi/Yoshitaka, Y.; Ozeki, Y.; Nishiyama, A.; Morishige, Y.; Minato, Y.; Baughn, A.; Matsumoto, S.
10.1101/2024.05.12.593797 — microbiology — Posted on 2024-05-13
2957 Risk-free polio vaccine: Recombinant expression systems for production of stabilised virus-like particles
Sherry, L.; Bahar, M. W.; Porta, C.; Fox, H.; Grehan, K.; Nasta, V.; Duyvesteyn, H. M.; de Colibus, L.; Marsian, J.; Murdoch, I.; Ponndorf, D.; Kim, S.-R.; Shah, S.; Carlyle, S.; Swanson, J. J.; Matthews, S.; Nicol, C.; Lomonossoff, G. P.; Macadam, A. J.; Fry, E. E.; Stuart, D. I.; Stonehouse, N. J.; Rowlands, D. J.
10.1101/2024.05.13.593909 — microbiology — Posted on 2024-05-13
2958 Effect of 2,4-Dinitrophenol Against Multidrug-Resistant Bacteria
Perez Carrillo, V. H.; Nunez Vazquez, A. A.; Ortega Munoz, R.; Jimenez-Castellanos, J. C.; Montiel Aguirre, J. F.
10.1101/2024.05.13.593958 — microbiology — Posted on 2024-05-13
2959 Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis
Bauman, A. A.; Sarathy, J. P.; Kaya, F.; Massoudi, L. M.; Scherman, M. S.; Hastings, C.; Liu, J.; Xie, M.; Brooks, E. J.; Ramey, M. E.; Jones, I. L.; Benedict, N. D.; Maclaughlin, M. R.; Miller-Dawson, J. A.; Waidyarachchi, S. L.; Butler, M. M.; Bowlin, T. L.; Zimmerman, M. D.; Lenaerts, A. J.; Meibohm, B.; Gonzalez-Juarrero, M.; Lyons, M. A.; Dartois, V. A.; Lee, R. E.; Robertson, G. T.
10.1101/2024.05.13.593953 — microbiology — Posted on 2024-05-13
2961 FtsN coordinates septal peptidoglycan synthesis and degradation through self-interaction of SPOR in E. coli
Lyu, Z.; Yang, X.; Yahashiri, A.; Ha, S.; McCausland, J. W.; Britton, B. M.; Weiss, D. S.; Xiao, J.
10.1101/2024.05.13.594014 — microbiology — Posted on 2024-05-13
2962 Analysis of differential expression of matrix metalloproteins and defensins in the nasopharyngeal milieu of mild and severe COVID-19 cases
Imtiaz, K.; Farooqui, N.; Ahmed, K.; Zhamalbekova, A.; Anwar, M. F.; Gul, K.; Hussain, A.; Sarria-Santamera, A.; Abidi, S. H.
10.1101/2024.05.12.593784 — microbiology — Posted on 2024-05-13
2963 Persistent Activation of Chronic Inflammatory Pathways in Long Covid
Aid, M.; McMahan, K.; Hachmann, N.; Miller, J.; Borducchi, E.; Hope, D.; Rowe, M.; Schonberg, E.; Thai, S.; Collier, A.-r.; Mullington, J.; Barouch, D.
10.1101/2024.05.11.593709 — immunology — Posted on 2024-05-13
2964 S-PLM: Structure-aware Protein Language Model via Contrastive Learning between Sequence and Structure
Wang, D.; Pourmirzaei, M.; Abbas, U. L.; Zeng, S.; Manshour, N.; Esmaili, F.; Poudel, B.; Jiang, Y.; Shao, Q.; Chen, J.; Xu, D.
10.1101/2023.08.06.552203 — bioinformatics — Posted on 2024-05-13
2965 Spectro-temporal acoustical markers differentiate speech from song across cultures
Albouy, P.; Mehr, S. A.; Hoyer, R. S.; Ginzburg, J.; Du, Y.; Zatorre, R. J.
10.1101/2023.01.29.526133 — neuroscience — Posted on 2024-05-13
2969 Characterizing substructure via mixture modeling in large-scale genetic summary statistics
Stoneman, H. R.; Price, A.; Scribner-Trout, N.; Lamont, R.; Tifour, S.; Pozdeyev, N.; Crooks, K.; Lin, M.; Rafaels, N.; Marker, K. M.; Gignoux, C. R.; Hendricks, A. E.
10.1101/2024.01.29.577805 — genomics — Posted on 2024-05-13
2970 Evolution in response to an abiotic stress shapes species coexistence
Fragata, I.; Godinho, D. P.; Rodrigues, L. R.; Cruz, M. A.; Zele, F.; Godoy, O.; Magalhaes, S.
10.1101/2023.05.06.539716 — evolutionary biology — Posted on 2024-05-13
2973 Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart
Ohanele, C.; Peoples, J. N.; Karlstaedt, A.; Geiger, J. T.; Gayle, A. D.; Ghazal, N.; Sohani, F.; Brown, M. E.; Davis, M. E.; Porter, G. A.; Faundez, V.; Kwong, J. Q.
10.1101/2023.05.22.541833 — developmental biology — Posted on 2024-05-13
2974 A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity
Alexander, M.; Upadhyay, V.; Rock, R.; Ramirez, L.; Trepka, K.; Puchalska, P.; Orellana, D.; Ang, Q. Y.; Whitty, C.; Turnbaugh, J. A.; Tian, Y.; Dumlao, D.; Nayak, R. R.; Patterson, A. D.; Newman, J. C.; Crawford, P. A.; Turnbaugh, P. J.
10.1101/2023.11.02.565382 — microbiology — Posted on 2024-05-13
2976 Regional response to light illuminance across the human hypothalamus
Campbell, I.; Sharifpour, R.; Balda, F.; Beckers, E.; Paparella, I.; Berger, A.; Koshmanova, E.; Mortazavi, N.; Read, J.; Zubkov, M.; Talwar, P.; Collette, F.; Sherif, S.; Phillips, C.; Lamalle, L.; Vandewalle, G.
10.1101/2023.12.19.572317 — neuroscience — Posted on 2024-05-13
2977 Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration
Rademacher, K. L.; Doric, Z.; Haddad, D.; Mamaligas, A.; Liao, S.-C.; Creed, R.; Kano, K.; Chatterton, Z.; Fu, Y.; Garcia, J. H.; Vance, V.; Sei, Y.; Kreitzer, A.; Halliday, G.; Nelson, A.; Margolis, E.; Nakamura, K. L.
10.1101/2024.04.05.588321 — neuroscience — Posted on 2024-05-13
2978 Tonic dendritic GABA release by substantia nigra dopaminergic neurons
Simmons, D. V.; Moreno-Ramos, O. A.; Raj, D. D. A.; Kaganovsky, K.; Ding, J.; Awatramani, R. V.; Wilson, C.; Surmeier, D. J.
10.1101/2024.03.27.586699 — neuroscience — Posted on 2024-05-13
2980 Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis
Calhoon, D.; Sang, L.; Bezwada, D.; Kim, N.; Basu, A.; Hsu, S.-C.; Pimentel, A.; Brooks, B.; La, K.; Paulina Serrano, A.; Cassidy, D. L.; Cai, L.; Toffessi-Tcheuyap, V.; Margulis, V.; Cai, F.; Brugarolas, J.; Weiss, R. J.; DeBerardinis, R. J.; Birsoy, K.; Garcia-Bermudez, J.
10.1101/2024.05.13.593939 — cancer biology — Posted on 2024-05-13
2981 Histone Modifications and miRNA Perturbations Contribute to Transcriptional Dysregulation of Hypertrophy in Obstructive Hypertrophic Cardiomyopathy
Garmany, R.; Dasari, S.; Bos, J. M.; Kim, E. T.; Tester, D. J.; dos Remedios, C.; Maleszewski, J. J.; Robertson, K. D.; Dearani, J. A.; Ommen, S. R.; Giudicessi, J. R.; Ackerman, M. J.
10.1101/2024.05.09.593374 — bioinformatics — Posted on 2024-05-13
2982 T-ChIC: multi-omic detection of histone modifications and full-length transcriptomes in the same single cell
Zeller, P.; Blotenburg, M.; Bhardwaj, V.; de Barbanson, B. A.; Salmen, F.; van Oudenaarden, A.
10.1101/2024.05.09.593364 — genomics — Posted on 2024-05-13
2987 Detailing organelle division and segregation in Plasmodium falciparum
Verhoef, J. M. J.; Boshoven, C.; Evers, F.; Akkerman, L. J.; Gijsbrechts, B. C. A.; van de Vegte-Bolmer, M.; van Gemert, G.-J.; Vaidya, A. B.; Kooij, T. W. A.
10.1101/2024.01.30.577899 — microbiology — Posted on 2024-05-13
2988 Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation
Isbister, J. B.; Ecker, A.; Pokorny, C.; Bolanos-Puchet, S.; Egas Santander, D.; Arnaudon, A.; Awile, O.; Barros-Zulaica, N.; Blanco Alonso, J.; Boci, E.; Chindemi, G.; Courcol, J.-D.; Damart, T.; Delemontex, T.; Dietz, A.; Ficarelli, G.; Gevaert, M.; Herttuainen, J.; Ivaska, G.; Ji, W.; Keller, D.; King, J.; Kumbhar, P.; Lapere, S.; Litvak, P.; Mandge, D.; Muller, E. B.; Pereira, F.; Planas, J.; Ranjan, R.; Reva, M.; Romani, A.; Rössert, C.; Schürmann, F.; Sood, V.; Teska, A.; Tuncel, A.; Van Geit, W.; Wolf, M.; Markram, H.; Ramaswamy, S.; Reimann, M. W.
10.1101/2023.05.17.541168 — neuroscience — Posted on 2024-05-13
2989 Trigeminal innervation and tactile responses in mouse tongue
Zhang, L.; Nagel, M.; Olson, W. P.; Chesler, A. T.; O'Connor, D. H.
10.1101/2023.08.17.553449 — neuroscience — Posted on 2024-05-13
2992 Hypocotyl Development in Arabidopsis and other Brassicaceae Displays Evidence of Photoperiodic Memory
Ronald, J.; Lock, S. C. L.; Claydon, W.; Zhu, Z.; McCarthy, K.; Pendlington, E.; Redmond, E. J.; Vong, G. Y. W.; Stanislas, S. P.; Davis, S. J.; Quint, M.; Ezer, D.
10.1101/2024.05.13.593876 — plant biology — Posted on 2024-05-13
2995 Crossroads of assembling a moss genome: navigating contaminants and horizontal gene transfer in the moss Physcomitrellopsis africana
Vuruputoor, V. S.; Starovoitov, A.; Cai, Y.; Liu, Y.; Rahmatpour, N.; Hedderson, T. A.; Wilding, N.; Wegrzyn, J. L.; Goffinet, B.
10.1101/2023.10.30.564737 — genomics — Posted on 2024-05-13
2998 Accurate bacterial outbreak tracing with Oxford Nanopore sequencing and reduction of methylation-induced errors
Lohde, M.; Wagner, G. E.; Dabernig-Heinz, J.; Viehweger, A.; Braun, S. D.; Monecke, S.; Diezel, C.; Stein, C.; Marquet, M.; Ehricht, R.; Pletz, M. W.; Brandt, C.
10.1101/2023.09.15.556300 — molecular biology — Posted on 2024-05-13
2999 A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation
Polinski, P.; Miret-Cuesta, M.; Zamora-Moratalla, A.; Mantica, F.; Cantero-Recasens, G.; Normanno, D.; Iniguez-Rabago, L.; Morenilla-Palao, C.; Ordono, P.; Bonnal, S.; Ellis, J.; Gomez-Riera, R.; De Lagran, M. M.; Fernandez-Blanco, A.; Rodriguez-Marin, C.; Permanyer, J.; Folsz, O.; Dominguez, E.; Sierra, C.; Legutko, D.; Wojnacki, J.; Musoles-Lleo, J. L.; Blencowe, B.; Herrera, E.; Dierssen, M.; Irimia, M.
10.1101/2023.01.12.523772 — neuroscience — Posted on 2024-05-13
3002 Comparative Analysis of Small Secreted Peptide Signaling during Defense Response: Insights from Vascular and Non-Vascular Plants
Lyapina, I.; Ganaeva, D.; Rogozhin, E. A.; Ryabukhina, E. V.; Ryazantsev, D. Y.; Mamaeva, A.; Fesenko, I.
10.1101/2024.05.13.593875 — plant biology — Posted on 2024-05-13
3006 A Tale of Two Parasites: A Glimpse into the clinical RNA Methylome of P. falciparum and P. vivax isolates
Roy, P.; Gujarati, S.; Gupta, P.; Gupta, I.; Mahapatra, T.; Gupta, D.; Kochar, S. K.; Kochar, D. K.; Das, A.
10.1101/2023.12.26.573234 — genomics — Posted on 2024-05-13
3011 The brassinosteroid receptor gene BRI1 safeguards cell-autonomous brassinosteroid signaling across tissues
Blanco-Tourinan, N.; Rana, S.; Nolan, T. M.; Li, K.; Vukasinovic, N.; Hsu, C.-W.; Russinova, E.; Hardtke, C.
10.1101/2024.05.13.593848 — plant biology — Posted on 2024-05-13
3013 Cytokinin-induced immunity enhances rice blast resistance
Chanclud, E.; Kisiala, A.; Emery, N. R. J.; Mouille, G.; Boutet, S.; Romiti-Michel, C.; Morel, J.-B.
10.1101/2024.05.10.593599 — plant biology — Posted on 2024-05-13
3014 Wheat Enhanced Disease Resistance EMS-Mutants Include Lesion-mimics With Adult Plant Resistance to Stripe Rust
Lunde, C.; Seong, K.; Kumar, R.; Deatker, A.; Chhabra, B.; Wang, M.; Kaur, S.; Song, S.; Palayur, A.; Davies, C.; Cumberlich, W.; Gill, U.; Rawat, N.; Chen, X.; Aoun, M.; Mundt, C.; Krasileva, K. V.
10.1101/2024.05.10.593581 — plant biology — Posted on 2024-05-13
3015 Influence of Monosporascus root rot and vine decline disease on the amino acid metabolism of watermelon fruit
Santo, H.; Tadano, S.; Inokami, F.; Nishioka, T.; Konaka, T.; Sakata, M.; Morimoto, Y.; Akashi, K.
10.1101/2024.05.11.593714 — plant biology — Posted on 2024-05-13
3017 Galacturonic acid oxidation: a radical way to stick together
Grandjean, C.; Voxeur, A.; Chabout, S.; Stephanie, B.; Pelloux, J.; Bouton, S.; Mouille, G.
10.1101/2024.05.13.590697 — plant biology — Posted on 2024-05-13
3019 Trophic adaptation of large terrestrial omnivores to global change
Albrecht, J.; Bocherens, H.; Hobson, K. A.; Drucker, D. G.; Sergiel, A.; Swenson, J. E.; Zedrosser, A.; Marciszak, A.; Iregren, E.; Drenzel, L.; Kysely, R.; Lipecki, G.; Makowiecki, D.; Wagner, J.; Zwijacz-Kozica, T.; Fritz, S. A.; Revilla, E.; Selva, N.
10.1101/2024.05.07.590891 — ecology — Posted on 2024-05-13
3021 Species richness patterns in Fijian bees are explained by constraints in physiological traits
da Silva, C. R. B.; Dorey, J. B.; Matthews, C. S.; Parslow, B.; Tuiwawa, M.; Beaman, J. E.; Congedi, N. C.; Barker, S. J.; Hughes, P. M.; Blumson, R. T. E.; Stevens, M. I.; Schwarz, M. P.; Gloag, R.; Kellermann, V.
10.1101/2024.05.09.593294 — evolutionary biology — Posted on 2024-05-13
3022 Modelling resource-driven movements of livestock herds to predict the impact of climate change on network dynamics
Sulaimon, T. A.; Ekwem, D.; Finch, D.; Palmer, P. I.; Cleaveland, S.; Enright, J.; Johnson, P. C. D.; Kao, R. R.
10.1101/2024.05.09.593362 — ecology — Posted on 2024-05-13
3023 Chaperonin-mediated Winter Cold Response via Circadian Clock Components in Arabidopsis
Jeong, G.; Jeon, M.; Kyung, J.; Jeong, D.; Shin, J.; Shin, Y.; Hwang, D.; Hyun, Y.; Lee, I.
10.1101/2024.05.09.593290 — plant biology — Posted on 2024-05-13
3025 Fast adaptive super-resolution lattice light-sheet microscopy for rapid, long-term, near-isotropic subcellular imaging
Qiao, C.; Li, Z.; Wang, Z.; Lin, Y.; Liu, C.; Zhang, S.; Liu, Y.; Feng, Y.; Wang, X.; Dong, X.; Guo, J.; Jiang, T.; Wang, Q.; Dai, Q.; Li, D.
10.1101/2024.05.09.593386 — biophysics — Posted on 2024-05-13
3026 Asymmetric binding of coactivator SRC1 to FXR-RXR and allosteric communication within the complex
Sheng, Y.; Guo, Y.; Sun, M.; Dong, Y.; Yin, Y.; Wang, Y.; Peng, C.; Xu, Y.; Wang, N.; Liu, J.
10.1101/2024.05.13.593894 — biophysics — Posted on 2024-05-13
3027 Migration, proliferation, and elasticity of bladder cancer cells on lectin-coated surfaces
Luty, M.; Szydlak, R.; Pabijan, J.; Oevreeide, I. H.; Prot, V. E.; Stokke, B. T.; Lekka, M.
10.1101/2024.05.12.593008 — biophysics — Posted on 2024-05-13
3028 Impedance-based assay for pan-cancer early and rapid detection of cell-free DNA
Dube, T.; Prasad, P.; Swami, P.; Singh, A.; Verma, M.; Tanwar, P.; Chowdhury, S.; Gupta, S.
10.1101/2024.05.10.593096 — biophysics — Posted on 2024-05-13
3029 Gauge fixing for sequence-function relationships
Posfai, A.; Zhou, J.; McCandlish, D. M.; Kinney, J. B.
10.1101/2024.05.12.593772 — biophysics — Posted on 2024-05-13
3032 Crosstalk between plasma membrane and Staphylococcus α-hemolysin during oligomerization
Chatterjee, A.; Roy, A.; Satheesh, T.; Chakraborty, D.; Das, P. P.; Mondal, B.; Kishore, P.; Ghoshal, B.; Jhunjhunwala, S.; Ganji, M.; Dutta, S.
10.1101/2024.05.11.593496 — biophysics — Posted on 2024-05-13
3034 Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle
Mead, A. F.; Wood, N. B.; Nelson, S. R.; Palmer, B. M.; Yang, L.; Previs, S. B.; Ploysangngam, A.; Kennedy, G. G.; McAdow, J. F.; Tremble, S. M.; Cipolla, M. J.; Ebert, A. M.; Johnson, A. N.; Gurnett, C. A.; Previs, M. J.; Warshaw, D. M.
10.1101/2024.05.10.593199 — biophysics — Posted on 2024-05-13
3035 Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM
Kung, J. E.; Johnson, M. C.; Jao, C. C.; Arthur, C. P.; Tegunov, D.; Rohou, A.; Sudhamsu, J.
10.1101/2024.05.10.593593 — biophysics — Posted on 2024-05-13
3046 X-ray Crystallographic and Hydrogen Deuterium Exchange Studies Confirm Alternate Kinetic Models for Homolog Insulin Monomers
Ayan, E.; Turk, M.; Tatli, O.; Bostan, S.; Telek, E.; Dingiloglu, B.; Dogan, B. Z.; Alp, M. I.; Kati, A.; Dinler Doganay, G.; Demirci, H.
10.1101/2024.04.16.589767 — biophysics — Posted on 2024-05-13
3047 The replicative helicase CMG is required for the divergence of cell fates during asymmetric cell division in vivo
Memar, N.; Sherrard, R.; Sethi, A.; Lloret Fernandez, C.; Schmidt, H.; Lambie, E.; Poole, R.; Schnabel, R.; Conradt, B.
10.1101/2024.05.09.593335 — cell biology — Posted on 2024-05-13
3048 TMEM165 replenishes lysosomal calcium stores, protects cells against calcium overload, and mediates calcium-induced lysosomal H+ leakage
Chan, R.; Liu, B.; Jaslan, D.; Kujec, L.; Kurdina, V.; Warnke, B.; Klingl, Y.; Petrauskas, A.; Maeda, K.; Grimm, P. D. D. C. M.; Jaattela, M.
10.1101/2024.05.09.593345 — cell biology — Posted on 2024-05-13
3049 Detection of tomato brown rugose fruit virus in environmental residues: the importance of contextualizing test results
Giesbers, A. K.; Vogel, E.; Skelton, A.; Zisi, Z.; Wildhagen, M.; Loh, Y. L.; Ghijselings, L.; Groothuismink, J.; Westenberg, M.; Matthijnssens, J.; Roenhorst, A.; Vos, C.; Fox, A.; Botermans, M.
10.1101/2024.04.25.591117 — microbiology — Posted on 2024-05-13
3050 Neural interactions in the human frontal cortex dissociate reward and punishment learning
Combrisson, E.; Basanisi, R.; Gueguen, M.; Rheims, S.; Kahane, P.; Bastin, J.; Brovelli, A.
10.1101/2023.05.02.539138 — neuroscience — Posted on 2024-05-13
3053 Perivascular adipose tissue remodeling impairs vasoreactivity in thermoneutral-housed rats
Henckel, M.; Chun, J. H.; Knaub, L.; Pott, G.; James, G.; Hunter, K.; Shandas, R.; Walker, L.; Reusch, J.; Keller, A.
10.1101/2024.05.09.593330 — physiology — Posted on 2024-05-13
3055 Single-cell transcriptional and epigenetic mapping reveals cellular and molecular mechanisms driving non-ischemic cardiac fibrosis
Krstevski, C.; Farrugia, G. E.; Hsu, i.; Dona, M. S. I.; Gaynor, T. L.; Cohen, C. D.; Harper, R. L.; Harrison, T. I.; Claridge, B.; Drack, A.; Lelliott, P.; Kiriazis, H.; Brown, A.; McMullen, J. R.; Donner, D. G.; Lal, S.; Greening, D. W.; Pinto, A. R.
10.1101/2024.05.09.593315 — cell biology — Posted on 2024-05-13
3058 Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex.
Ge, T.; Brickner, D. G.; Zehr, K.; VanBelzen, J.; Zhang, W.; Caffalette, C.; Ungerleider, S.; Marcou, N.; Chait, B.; Rout, M.; Brickner, J.
10.1101/2024.05.09.593355 — cell biology — Posted on 2024-05-13
3059 N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs
Lee, E. S.; Smith, H. W.; Wang, Y. E.; Ihn, S. S.; Scalize de Olivera, L.; Kejiou, N. S.; Liang, Y. L.; Nabeel-Shah, S.; Jomphe, R. Y.; Pu, S.; Greenblatt, J. F.; Palazzo, A. F.
10.1101/2023.06.20.545713 — molecular biology — Posted on 2024-05-13
3060 DivIVA controls the dynamics of septum splitting and cell elongation in Streptococcus pneumoniae
Trouve, J.; Zapun, A.; Bellard, L.; Juillot, D.; Pelletier, A.; Freton, C.; Baudoin, M.; Carballido-Lopez, R.; Campo, N.; Wong, Y.-S.; Grangeasse, C.; Morlot, C.
10.1101/2024.05.09.593393 — microbiology — Posted on 2024-05-13
3061 Salt supersaturation as accelerator of influenza A virus inactivation in 1-μl droplets
Schaub, A.; Luo, B.; David, S. C.; Glas, I.; Klein, L. K.; Costa, L.; Terrettaz, C.; Bluvshtein, N.; Motos, G.; Violaki, K.; Pohl, M.; Hugentobler, W.; Nenes, A.; Stertz, S.; Krieger, U. K.; Peter, T.; Kohn, T.
10.1101/2023.12.21.572782 — microbiology — Posted on 2024-05-13
3062 UPF1 is required for gene expression in mitochondria and for the elimination of paternal mtDNA
Wright, M. T.; Singh, A. K.; Dixon, H. L.; Price, E. M.; Connolly, E. C.; di Maio, A.; Barlow, J. P.; Catoni, M.; Fan, Y.; Brogna, S.
10.1101/2024.05.10.591322 — cell biology — Posted on 2024-05-13
3067 Emergent Simplicities in Stochastic Intergenerational Homeostasis
Joshi, K.; Wright, C. S.; Ziegler, K. F.; Spiers, E. M.; Crosser, J. T.; Eschker, S.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.01.18.524627 — biophysics — Posted on 2024-05-12
3068 A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons
Szabo, D.; Franke, V.; Bianco, S.; Batiuk, M. Y.; Paul, E. J.; Kukalev, A.; Pfisterer, U. G.; Irastorza-Azcarate, I.; Chiariello, A. M.; Demharter, S.; Zea Redondo, L.; Lopez-Atalaya, J. P.; Nicodemi, M.; Khodosevich, K.; Akalin, A.; Ungless, M. A.; Winick-Ng, W.; Pombo, A.
10.1101/2024.05.10.593308 — genomics — Posted on 2024-05-12
3069 Legionella uses host Rab GTPases and BAP31 to create a unique ER niche
Chadha, A.; Yanai, Y.; Oide, H.; Wakana, Y.; Inoue, H.; Saha, S.; Tagaya, M.; Arasaki, K.; Mukherjee, S.
10.1101/2024.05.10.593622 — cell biology — Posted on 2024-05-12
3070 Coumarin as a general switching auxiliary to prepare photochromic and spontaneously blinking fluorophores
Jradi, F.; English, B. P.; Brown, T. A.; Arron, J.; Khuon, S.; Galbraith, J. A.; Galbraith, C. G.; Lavis, L. D.
10.1101/2024.05.12.593749 — cell biology — Posted on 2024-05-12
3072 Full-length tRNAs lacking a functional CCA tail are selectively sorted into the lumen of extracellular vesicles
Scheepbouwer, C.; Aparicio-Puerta, E.; Gomez-Martin, C.; van Eijndhoven, M. A. J.; Drees, E. E. E.; Bosch, L.; de Jong, D.; Wurdinger, T.; Zijlstra, J. M.; Hackenberg, M.; Gerber, A.; Pegtel, D. M.
10.1101/2024.05.12.593148 — molecular biology — Posted on 2024-05-12
3074 Channel width modulates the permeability of DNA origami based nuclear pore mimics
Feng, Q.; Saladin, M.; Wu, C.; Cao, E.; Zheng, W.; Zhang, A.; Bhardwaj, P.; Li, X.; Shen, Q.; Kapinos, L. E.; Mariappan, M.; Lusk, C. P.; Xiong, Y.; Lim, R. Y. H.; Lin, C.
10.1101/2024.05.09.593438 — biophysics — Posted on 2024-05-12
3078 Predicting transcriptional activation domain function using Graph Neural Networks
Farheen, F.; Broyles, B. K.; Zhang, Y.; Ibtehaz, N.; Erkine, A. M.; Kihara, D.
10.1101/2024.05.08.593266 — bioinformatics — Posted on 2024-05-12
3079 Lateral Flow Assay Sensitivity and Signal Enhancement via Laser Micro-Machined Constrains in Nitrocellulose Membrane
Khatmi, G.; Klinavicius, T.; Simanavicius, M.; Silimavicius, L.; Tamuleviciene, A.; Rimkute, A.; Kucinskaite-Kodze, I.; Gylys, G.; Tamulevicius, T.
10.1101/2024.05.09.593095 — bioengineering — Posted on 2024-05-12
3080 A real-time biochemical assay for quantitative analyses of APOBEC-catalyzed DNA deamination
Belica, C. A.; Carpenter, M. A.; Chen, Y.; Brown, W. L.; Moeller, N. H.; Boylan, I. T.; Harris, R. S.; Aihara, H.
10.1101/2024.05.11.593688 — biochemistry — Posted on 2024-05-12
3081 Rapid, Reliable, and Interpretable CNV Curation Visualizations for Diagnostic Settings with SeeNV
Bradshaw, M. S.; Raychaudhuri, J.; Murphy, L.; Barnard, R.; Firman, T.; Gaskell, A.; Layer, R.
10.1101/2024.05.08.593244 — genomics — Posted on 2024-05-12
3083 Centromeres are Hotspots for Chromosomal Inversions and Breeding Traits in Mango
Wilkinson, M. J.; McLay, K.; Kainer, D.; Elphinstone, C.; Dillon, N. L.; Webb, M.; Wijesundara, U. K.; Ali, A.; Bally, I. S. E.; Munyengwa, N.; Furtado, A.; Henry, R. J.; Hardner, C. M.; Ortiz-Barrientos, D.
10.1101/2024.05.09.593432 — genomics — Posted on 2024-05-12
3084 Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening
Khan, T. G.; Bragazzi Cunha, J.; Raut, C.; Burroughs, M.; Goonewardena, S. N.; Smrcka, A. V.; Speliotes, E. K.; Emmer, B. T.
10.1101/2024.05.11.593568 — genetics — Posted on 2024-05-12
3086 MLT-11 is a transient apical extracellular matrix component required for cuticle patterning and function
Ragle, J. M.; Turzo, A.; Levenson, M. T.; Jonnalagadda, K.; Jackson, A.; Vo, A. A.; Pham, V. T.; Ward, J. D.
10.1101/2024.05.12.593762 — developmental biology — Posted on 2024-05-12
3092 Clonal sharing of CD8+ T-cells links skin and joint inflammation in psoriatic arthritis
Durham, L. E.; Humby, F.; Ng, N.; Gray, E. H.; Ryan, S. E.; Ross, R.; Povoleri, G. A. M.; Nuamah, R.; Fung, K.; Kallayil, A. M.; Dhami, P.; Kirkham, B. W.; Taams, L. S.
10.1101/2024.05.09.593313 — immunology — Posted on 2024-05-12
3094 SCO-pH: Microfluidic dynamic phenotyping platform for high-throughput screening of single cell acidification
Jeong, H.; Leyes Porello, E. A.; Rosario, J. G.; Kuang, D.; Han, S. H.; Sul, J.-Y.; Lim, B.; Lee, D.; Kim, J.
10.1101/2024.05.08.593179 — bioengineering — Posted on 2024-05-12
3096 Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII.4 and GII.17
Tagawa, J.; Yanaka, S.; Kato, Y.; Masuda, A.; Lee, J. M.; Senoo, A.; Oyama, K.; Nishida, M.; Kusakabe, T.; Caaveiro, J. M. M.
10.1101/2024.05.11.593658 — biochemistry — Posted on 2024-05-12
3097 Perturbation-Specific Transcriptional Mapping for unbiased target elucidation of antibiotics.
Romano, K. P.; Bagnall, J.; Warrier, T.; Sullivan, J.; Ferrara, K.; Orzechowski, M.; Nguyen, P.; Raines, K.; Livny, J.; Shoresh, N.; Hung, D.
10.1101/2024.04.25.590978 — genomics — Posted on 2024-05-12
3102 GpsB is an accessory Z-ring anchor
Bhattacharya, D.; McKnight, L.; King, A.; Eswara, P. J.
10.1101/2024.05.11.593517 — microbiology — Posted on 2024-05-12
3103 Engineered Bacillus subtilis as oral probiotics to enhance clearance of blood lactate
Yang, M.; Hutchinson, N.; Ye, N.; Yin, J.; Guan, M.; Wang, Z.; Chen, P.; Yang, S.; Crane, J. D.; Zhang, K.; He, X.; Li, J.
10.1101/2023.11.30.569300 — synthetic biology — Posted on 2024-05-12
3104 Post-translation digital data encoding into the genomes of mammalian cell populations
Callisto, A.; Strutz, J.; Leeper, K.; Kalhor, R.; Church, G.; Tyo, K.; Bhan, N.
10.1101/2024.05.12.591851 — synthetic biology — Posted on 2024-05-12
3106 The killifish germline regulates longevity and somatic repair in a sex-specific manner
Moses, E.; Atlan, T.; Sun, X.; Franek, R.; Siddiqui, A.; Marinov, G. K.; Shifman, S.; Zucker, D. M.; Oron-Gottesman, A.; Greenleaf, W. J.; Cohen, E.; Ram, O.; Harel, I.
10.1101/2023.12.18.572041 — genetics — Posted on 2024-05-12
3107 D--hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.
Kula, B.; Antal, B.; Weistuch, C.; Gackiere, F.; Barre, A.; Velado, V.; Hubbard, J. M.; Kukley, M.; Mujica-Parodi, L. R.; Smith, N. A.
10.1101/2023.08.23.554428 — neuroscience — Posted on 2024-05-12
3108 Mechanism of Phosphate Release from Actin Filaments
Wang, Y.; Wu, J.; Zsolnay, V.; Pollard, T. D.; Voth, G. A.
10.1101/2023.08.03.551904 — biophysics — Posted on 2024-05-12
3110 Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution
Ma, H.; Srivastava, S.; Ong, X.; Tay, S. T.; Xu, C.; Sheng, T.; Ho, S. W. T.; Lian, B. S. X.; Huang, K. K.; Goh, Y. T.; Joseph, C. R. C.; Lum, J. H. Y.; Tan, A. L. K.; Zhang, Y.; NG, M. S. W.; Zhu, F.; Zhao, J. J.; Teh, M.; Yeong, J.; Yong, W. P.; So, J. B. Y.; Sundar, R.; Tan, P.
10.1101/2024.05.08.593271 — cancer biology — Posted on 2024-05-12
3112 Identifying Candidate Genes for Sugar Accumulation in Sugarcane Cultivars: From a Syntenic Genomic Region to a Gene Coexpression Network
Martins, M. L. T.; Sforca, D. A.; dos Santos, L. P.; Pimenta, R. J. G.; Mancini, M. C.; Aono, A. H.; da Silva, C. B. C.; Vautrin, S.; Bellec, A.; Vicentini, R.; Berges, H.; da Silva, C. C.; de Souza, A. P.
10.1101/2024.05.08.593213 — genomics — Posted on 2024-05-12
3114 Standardized Nomenclature and Reporting for PacBio HiFi Sequencing and Analysis of rAAV Gene Therapy Vectors
Talevich, E.; Tseng, E.; Diallo, A.; Sellami, N.; Elliott, A.; Cantarel, B. L.; Tonthat, N.; Chatterjee, P.; Tai, P. W. L.; Aldridge, C.
10.1101/2024.05.07.592296 — bioinformatics — Posted on 2024-05-12
3115 Context dependent activity of p63-bound gene regulatory elements
McCann, A. A.; Baniulyte, G.; Woodstock, D.; Sammons, M. A.
10.1101/2024.05.09.593326 — genomics — Posted on 2024-05-12
3116 In vitro spatiotemporal reconstruction of human skeletal muscle organogenesis
Mavrommatis, L.; Daya, N.; Volke, L.; Lu, I.-N.; Zhuge, H.; Stehling, M.; Zeuschner, D.; Jeong, H.-W.; Yang, J. H.; Meyer zu Horste, G.; Brand-Saberi, B.; Scholer, H. R.; Vorgerd, M.; Zaehres, H.
10.1101/2024.05.10.593520 — developmental biology — Posted on 2024-05-12
3117 Associations Between Prenatal Vitamin D and Placental Gene Expression
Parenti, M.; Melough, M. M.; Lapehn, S.; MacDonald, J.; Firsick, E. J.; Choi, H. Y.; Derefinko, K. J.; Enquobahrie, D. A.; Carroll, K. N.; LeWinn, K. Z.; Bush, N. R.; Zhao, Q.; Sathyanarayana, S.; Paquette, A. G.
10.1101/2024.05.10.593571 — developmental biology — Posted on 2024-05-12
3121 Alternative splicing of clock transcript mediates the response of circadian clocks to temperature changes
Cai, Y. D.; Chow, G. K.; Hidalgo, S.; Liu, X.; Jackson, K. C.; Vasquez, C. D.; Gao, Y. Z.; Lam, V. H.; Tabuloc, C. A.; Zheng, H.; Zhao, C.; Chiu, J. C.
10.1101/2024.05.10.593646 — neuroscience — Posted on 2024-05-12
3122 Accelerated protein retention expansion microscopy using microwave radiation
Bullard, M. R.; Cervantes, J. C. M.; Quaicoe, N. B.; Jin, A.; Adams, D.; Lin, J. M.; Iliadis, E.; Seidler, T. M.; Cervantes Sandoval, I.; He, H.-y.
10.1101/2024.05.11.593228 — neuroscience — Posted on 2024-05-12
3124 Non-canonical function of ADAM10 in presynaptic plasticity
Baer, J.; Fanutza, T.; Reimann, C.; Seipold, L.; Grohe, M.; Bolter, J. R.; Delfs, F.; Bucher, M.; Gee, C. E.; Schweizer, M.; Saftig, P.; Mikhaylova, M.
10.1101/2024.05.12.593731 — neuroscience — Posted on 2024-05-12
3125 Distinct molecular and functional properties of human induced-proprioceptor and low-threshold mechanoreceptor neurons
Hulme, A. J.; Finol-Urdaneta, R. K.; McArthur, J. R.; Marzano, N. R.; Maksour, S.; Thind, A. S.; Guo, Y.; Kaul, D.; Maddock, M.; Friedrich, O.; Martinac, B.; Adams, D. J.; Dottori, M.
10.1101/2024.05.12.593730 — neuroscience — Posted on 2024-05-12
3126 PTPRS is a novel marker for early tau pathology and synaptic integrity in Alzheimer's disease
Poirier, A.; Picard, C.; Labonte, A.; Aubry, I.; Auld, D.; Zetterberg, H.; Blennow, K.; the PREVENT-AD research group, ; Tremblay, M.; Poirier, J.
10.1101/2024.05.12.593733 — neuroscience — Posted on 2024-05-12
3127 Learning to handle flowers increases pollen collection benefits for bees but does not affect pollination success for plants
Mayberry, M. M.; Naumer, K. C.; Novinger, A. N.; McCart, D. M.; Wilkins, R. V.; Muse, H.; Ashman, T.-L.; Russell, A. L.
10.1101/2024.05.10.593657 — animal behavior and cognition — Posted on 2024-05-12
3131 Intradental mechano-nociceptors serve as sentinels that prevent tooth damage
Ronan, E. A.; Gandhi, A. R.; Constantinescu, B. S. C.; Uchima Koecklin, K. H.; Guenther, M. E.; Nagel, M.; Blumberg, K. J.; Stern, T.; Li, P.; Emrick, J. J.
10.1101/2024.05.11.593684 — neuroscience — Posted on 2024-05-12
3134 Neural mechanisms of resource allocation in working memory
Li, H.-H.; Sprague, T. C.; Yoo, A.; Ma, W. J.; Curtis, C. E.
10.1101/2024.05.11.593695 — neuroscience — Posted on 2024-05-12
3135 Spike-wave discharges during low-current thalamic deep brain stimulation in mice
Flores, F. J.; Dalla Betta, I.; Tauber, J.; Schreier, D.; Stephen, E. P.; Wilson, M. A.; Brown, E. N.
10.1101/2024.05.10.593558 — neuroscience — Posted on 2024-05-12
3136 Naturalistic acute pain states decoded from neural and facial dynamics
Huang, Y.; Gopal, J.; Kakusa, B.; Li, A.; Huang, W.; Wang, J. B.; Persad, A.; Ramayya, A.; Parvizi, J.; Buch, V. P.; Keller, C.
10.1101/2024.05.10.593652 — neuroscience — Posted on 2024-05-12
3137 Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping
Ector, C.; Schmal, C.; Didier, J.; De Landtsheer, S.; Finger, A.-M.; Müller-Marquardt, F.; Schulte, J.; Sauter, T.; Keilholz, U.; Herzel, H.; Kramer, A.; Granada, A. E.
10.1101/2023.11.30.569380 — cancer biology — Posted on 2024-05-12
3141 The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites
Zung, N.; Aravindan, N.; Boshnakovska, A.; Valenti, R.; Preminger, N.; Jonas, F.; Yaakov, G.; Willoughby, M.; Homberg, B.; Keller, J.; Kupervaser, M.; Dezorella, N.; Dadosh, T.; Wolf, S. G.; Itkin, M.; Malitsky, S.; Brandis, A.; Barkai, N.; Fernandez-Busnadiego, R.; Reddi, A.; Rehling, P.; Rapaport, D.; Schuldiner, M.
10.1101/2024.05.09.593285 — cell biology — Posted on 2024-05-12
3144 Unveiling genetic anchors in Saccharomyces cerevisiae: QTL mapping identifies IRA2 as a key player in ethanol tolerance and beyond
Tristao, L. E.; de Sousa, L. I. S.; Vargas, B. d. O.; Jose, J.; Carazzolle, M. F.; Silva, E. M.; Galhardo, J. P.; Pereira, G. A. G.; de Mello, F. d. S. B.
10.1101/2024.05.08.593158 — genetics — Posted on 2024-05-11
3147 Decoding Early Psychoses: Unraveling Stable Microstructural Features Associated with Psychopathology Across Independent Cohorts
Wang, H. R.; Liu, Z.-Q. R.; Nakua, H.; Hegarty, C. E.; Thies, M. B.; Patel, P. K.; Schleifer, C. H.; Boeck, T. P.; McKinney, R.; Currin, D.; Leathem, L.; DeRosse, P.; Bearden, C. E.; Misic, B. E.; Karlsgodt, K. H.
10.1101/2024.05.10.593636 — neuroscience — Posted on 2024-05-12
3148 eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer
Boyer, J. A.; Sharma, M.; Dorso, M.; Mai, N.; Amor, C.; Reiter, J. M.; Kannan, R.; Gadal, S.; Xu, J.; Miele, M.; Zhuoning, L.; Chen, X.; Chang, Q.; Pareja, F.; Worland, S.; Warner, D.; Sperry, S.; Chiang, G. G.; Thompson, P. A.; Yang, G.; Ouerfelli, O.; De Stanchina, E.; Wendel, H. G.; Rosen, E. Y.; Chandarlapaty, S.; Rosen, N.
10.1101/2024.05.08.593195 — cancer biology — Posted on 2024-05-11
3149 Metastasis founder cells activate immunosuppression early in human melanoma metastatic colonization
Guetter, S.; Koenig, C.; Koerkel-Qu, H.; Markiewicz, A.; Scheitler, S.; Katzer, M.; Berneburg, M.; Renner, P.; Cucuruz, B.; Guttenberger, L.; Naimer, V.; Weidele, K.; Treitschke, S.; Werno, C.; Jaser, H.; Bargmann, T.; Braun, A.; Weber, F.; Rachel, R.; Baumann, F.; Schmidleithner, L.; Schambeck, K.; Mohammadi, P.; Ulmer, A.; Haferkamp, S.; Klein, C. A.; Werner-Klein, M.
10.1101/2024.05.08.591627 — cancer biology — Posted on 2024-05-11
3153 Gradual labeling with fluorogenic probes for MINFLUX nanoscopy of densely packed structures
yao, l.; Si, D.; Chen, L.; Li, S.; Guan, J.; Ma, J.; zhang, q.; wang, j.; wang, l.; Gu, M.
10.1101/2024.05.08.593253 — biophysics — Posted on 2024-05-11
3155 Nanopore translocation reveals electrophoretic force on non-canonical RNA:DNA double helix
Boskovic, F. N.; Maffeo, C.; Patino Guillen, G.; Tivony, R.; Aksimentiev, A.; Keyser, U. F.
10.1101/2023.09.12.557357 — biophysics — Posted on 2024-05-11
3156 The Continuous Language of Protein Structure
Billera, L.; Oresten, A.; Stalmarck, A.; Sato, K.; Kaduk, M.; Murrell, B.
10.1101/2024.05.11.593685 — bioinformatics — Posted on 2024-05-11
3158 Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Brinda, K.; Lima, L.; Pignotti, S.; Quinones-Olvera, N.; Salikhov, K.; Chikhi, R.; Kucherov, G.; Iqbal, Z.; Baym, M.
10.1101/2023.04.15.536996 — bioinformatics — Posted on 2024-05-11
3160 B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure
Lovell, J. P.; Duque, C.; Rousseau, S.; Bhalodia, A.; Bermea, K.; Cohen, C. D.; Adamo, L.
10.1101/2024.05.08.593153 — immunology — Posted on 2024-05-11
3162 SCO-pH: Microfluidic dynamic phenotyping platform for high-throughput screening of single cell acidification
Jeong, H.; Leyes Porello, E. A.; Rosario, J. G.; Kuang, D.; Han, S. H.; Sul, J.-Y.; Lim, B.; Lee, D.; Kim, J.
10.1101/2024.05.08.593179 — bioengineering — Posted on 2024-05-11
3164 A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting
Birtwistle, M. R.; Huggins, J. R.; Zadeh, C. O.; Sarmah, D.; Srikanth, S.; Jones, B. K.; Cascio, L. N.; Dean, D. R.
10.1101/2024.05.10.593650 — biochemistry — Posted on 2024-05-11
3168 An MST-based assay reveals new binding preferences of IFIT1 for canonically and non-canonically capped RNAs
Spiewla, T.; Grab, K.; Depaix, A.; Ziemkiewicz, K.; Warminski, M.; Jemielity, J.; Kowalska, J.
10.1101/2024.05.10.593534 — biochemistry — Posted on 2024-05-11
3169 Heparan sulphate binding controls in vivo half-life of the HpARI protein family
Colomb, F.; Jamwal, A.; Ogunkanbi, A.; Frangova, T.; Savage, A. R.; Kelly, S.; Wright, G. J.; Higgins, M. K.; McSorley, H. J.
10.1101/2024.05.06.592731 — immunology — Posted on 2024-05-11
3173 Plasmodesmal closure elicits stress responses
Tee, E.; Breakspear, A.; Papp, D.; Thomas, H. R.; Walker, C.; Bellandi, A.; Faulkner, C.
10.1101/2024.05.08.593115 — plant biology — Posted on 2024-05-11
3176 Microbiota and metabolic adaptation shape Staphylococcus aureus virulence and antimicrobial resistance during intestinal colonization
Zhou, C.; Pawline, M. B.; Pironti, A.; Morales, S. M.; Perault, A. I.; Ulrich, R. J.; Podkowik, M. J.; Lejeune, A.; DuMont, A.; Stubbe, F.-X.; Korman, A.; Jones, D. R.; Schluter, J.; Richardson, A. R.; Fey, P. D.; Drlica, K.; Cadwell, K.; Torres, V. J.; Shopsin, B.
10.1101/2024.05.11.593044 — microbiology — Posted on 2024-05-11
3177 Asesino: a nucleus-forming phage that lacks PhuZ
Prichard, A.; Sy, A.; Meyer, J. R.; Villa, E.; Pogliano, J.
10.1101/2024.05.10.593592 — microbiology — Posted on 2024-05-11
3179 Highly accurate metagenome-assembled genomes from human gut microbiota using long-read assembly, binning, and consolidation methods
Portik, D. M.; Feng, X.; Benoit, G.; Nasko, D. J.; Auch, B.; Bryson, S. J.; Cano, R.; Carlin, M.; Damerum, A.; Farthing, B.; Grove, J. R.; Islam, M.; Langford, K. W.; Liachko, I.; Locken, K.; Mangelson, H.; Tang, S.; Zhang, S.; Quince, C.; Wilkinson, J. E.
10.1101/2024.05.10.593587 — microbiology — Posted on 2024-05-11
3180 A phosphorylation code coordinating transcription condensate dynamics with DNA replication
Marmolejo, C. O.; Sanchez, C.; Lee, J.; Werner, M.; Roberts, P.; Hamperl, S.; Saldivar, J. C.
10.1101/2024.05.10.593572 — molecular biology — Posted on 2024-05-11
3181 Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling
Navarro, G.; Gomez-Autet, M.; Morales, P.; Biel Rebassa, J.; Llinas del Torrent, C.; Jagerovic, N.; Pardo, L.; Franco, R.
10.1101/2024.05.10.593612 — molecular biology — Posted on 2024-05-11
3182 Visualization of intracellular ATP dynamics in the whole kidney under pathophysiological conditions using the kidney slice culture system
Yamamoto, S.; Yamamoto, S.; Takahashi, M.; Mii, A.; Okubo, A.; Toriu, N.; Nakagawa, S.; Abe, T.; Fukuma, S.; Imamura, H.; Yamamoto, M.; Yanagita, M.
10.1101/2024.05.11.592491 — molecular biology — Posted on 2024-05-11
3183 Bacterial Modulation of Intestinal Motility through Macrophage Redistribution
Ngo, J. S.; Amitabh, P.; Sokoloff, J. G.; Trinh, C.; Wiles, T. J.; Guillemin, K.; Parthasarathy, R.
10.1101/2024.05.10.593615 — microbiology — Posted on 2024-05-11
3184 Enterococcal quorum-controlled protease alters phage infection
Sheriff, E. K.; Salvato, F.; Andersen, S. E.; Chatterjee, A.; Kleiner, M.; Duerkop, B. A.
10.1101/2024.05.10.593607 — microbiology — Posted on 2024-05-11
3185 Molecular basis of foreign DNA recognition by BREX anti-phage immunity system
Drobiazko, A.; Adams, M.; Skutel, M.; Potekhina, K.; Matlashov, M.; Maxwell, K. L.; Blower, T. R.; Severinov, K.; Ghilarov, D.; Isaev, A.
10.1101/2024.04.12.589305 — molecular biology — Posted on 2024-05-11
3186 Complex genomic landscape of inversion polymorphism in Europe's most destructive forest pest
Mykhailenko, A.; Zielinski, P.; Bednarz, A.; Schlyter, F.; Andersson, M. N.; Antunes, B.; Borowski, Z.; Krokene, P.; Melin, M.; Morales-Garcia, J.; Müller, J.; Nowak, Z.; Schebeck, M.; Stauffer, C.; Viiri, H.; Zaborowska, J.; Babik, W.; Nadachowska-Brzyska, K.
10.1101/2023.10.10.561670 — evolutionary biology — Posted on 2024-05-11
3189 ATP burst is the dominant driver of antibiotic lethality in Mycobacteria
Lodhiya, T.; Palande, A.; Veeram, A.; Larrouy-Maumus, G.; Beste, D. J.; Mukherjee, R.
10.1101/2023.09.11.557291 — microbiology — Posted on 2024-05-11
3190 Acute sleep deprivation reduces fear memories in male and female mice
Foilb, A. R.; Taylor-Yeremeeva, E. M.; Schmidt, B. D.; Ressler, K. J.; Carlezon, W. A.
10.1101/2024.01.30.577985 — neuroscience — Posted on 2024-05-11
3191 Spatial risk of disease transmission between wild bovids and livestock in Thailand
Horpiencharoen, W.; Marshall, J. C.; Muylaert, R. L.; John, R. S.; Hayman, D. T. S.
10.1101/2024.05.04.592526 — ecology — Posted on 2024-05-11
3196 Plasmodium falciparum disruption of pericyte angiopoietin-1 secretion contributes to barrier breakdown in a 3D brain microvessel model
Long, R. K. M.; Korbmacher, F.; Ronchi, P.; Fleckenstein, H.; Schorb, M.; Mirza, W.; Mallorqui, M.; Aguilar, R.; Moncunill, G.; Schwab, Y.; Bernabeu, M.
10.1101/2024.03.29.587334 — microbiology — Posted on 2024-05-11
3197 An RXLR effector targets ER-Golgi interface to induce ER stress and necrotic cell death
Kim, J.; Kaleku, J.; Kim, H.; Kang, M.; Kang, H. J.; segonzac, c.; Woo, J.; Park, E.; Choi, D.
10.1101/2023.12.15.571945 — plant biology — Posted on 2024-05-11
3198 A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins
Grosskopf, J. D.; Sidabras, J. W.; Altenbach, C.; Anderson, J. R.; Mett, R. R.; Strangeway, R. A.; Hyde, J. S.; Hubbell, W. L.; Lerch, M. T.
10.1101/2024.05.07.593074 — biophysics — Posted on 2024-05-11
3200 Profiling Dynamic Patterns of Single-cell Motility
Maity, D.; Sivakumar, N.; Kamat, P.; Zamponi, N.; Min, C.; Du, W.; Jayatilaka, H.; Giri, A.; Johnston, A.; Starich, B.; Karl, M.; Agrawal, A.; Riley, D.; Venturitti, L.; Melnick, A.; Cerchietti, L.; Walston, J.; Phillip, J. M.
10.1101/2022.09.21.508955 — bioengineering — Posted on 2024-05-11
3201 Light regulates widespread plant alternative polyadenylation through the chloroplast
Kubaczka, M. G.; Godoy Herz, M. A.; Chen, W. C.; Zheng, D.; Petrillo, E.; Tian, B.; Kornblihtt, A. R.
10.1101/2024.05.08.593009 — molecular biology — Posted on 2024-05-10
3207 Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors
Patel, D. T.; Stogios, P. J.; Jaroszewski, L.; Urbanus, M. L.; Sedova, M.; Semper, C.; Le, C.; Takkouche, A.; Ichii, K.; Innabi, J.; Patel, D. H.; Ensminger, A. W.; Godzik, A.; Savchenko, A.
10.1101/2024.05.09.593423 — microbiology — Posted on 2024-05-11
3209 Presynaptic inhibition selectively suppresses leg proprioception in behaving Drosophila
Dallmann, C. J.; Luo, Y.; Agrawal, S.; Chou, G. M.; Cook, A.; Brunton, B. W.; Tuthill, J. C.
10.1101/2023.10.20.563322 — neuroscience — Posted on 2024-05-11
3210 Non-Invasive Brain Mapping Localizes Essential Language Function in Surgical Glioma Patients
Muir, M.; Noll, K.; Prinsloo, S.; Michener, H.; Asman, P.; Traylor, J.; Kumar, V.; Ene, C.; Liu, H.-L.; Prabhu, S.
10.1101/2024.05.06.592752 — neuroscience — Posted on 2024-05-11
3211 Characterizing substructure via mixture modeling of genetic similarity in large-scale summary statistics
Stoneman, H. R.; Price, A.; Scribner-Trout, N.; Lamont, R.; Tifour, S.; Pozdeyev, N.; Crooks, K.; Lin, M.; Rafaels, N.; Marker, K. M.; Gignoux, C. R.; Hendricks, A. E.
10.1101/2024.01.29.577805 — genomics — Posted on 2024-05-11
3212 Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries
Ortabozkoyun, H.; Huang, P.-Y.; Gonzalez-Buendia, E.; Cho, H.; Kim, S.; Tsirigos, A.; Mazzoni, E.; Reinberg, D.
10.1101/2023.04.25.538167 — genetics — Posted on 2024-05-11
3213 Lanthanide Cathodophores for Multicolor Electron Microscopy
Abdul Rehman, S.; Conway, J. B.; Nichols, A.; Soucy, E. R.; Dee, A.; Stevens, K.; Merminod, S.; MacNaughton, I.; Curtis, A.; Prigozhin, M. B.
10.1101/2023.12.11.570835 — biophysics — Posted on 2024-05-11
3214 Retinoic acid signaling suppresses chondrocyte identity during cartilage development and regeneration
Arata, C.; Paul, S.; Schindler, S.; Thiruppathy, M.; Flath, M.; Giovannone, D.; Hammer, Z.; Subramanie, D.; Crump, G.
10.1101/2024.05.10.593640 — developmental biology — Posted on 2024-05-11
3215 Activation of PKR by a short-hairpin RNA
Cottrell, K. A.; Ryu, S.; Donelick, H. M.; Mai, H.; Pierce, J. R.; Bass, B. L.; Weber, J. D.
10.1101/2024.05.08.592371 — molecular biology — Posted on 2024-05-10
3216 Yes Associated Transcriptional Regulator 1 (YAP1) and WW Domain Containing Transcription Regulator (WWTR1) are required for murine pregnancy initiation
Moldovan, G. E.; Massri, N.; Vegter, E. L.; Pauneto-Delgado, I. N.; Burns, G. W.; Joshi, N.; Gu, B.; Arora, R.; Fazleabas, A. T.
10.1101/2024.05.09.592984 — molecular biology — Posted on 2024-05-10
3220 Striatal output regulates the postnatal maturation of cortical circuits
Deemyad, T.; Janecek, M.; Shih, Y.-C.; Valle, V.; D'Agostino, A.; Perez, M.; Ketchesin, K.; Silva, S.; Peixoto, R.
10.1101/2024.05.10.593512 — neuroscience — Posted on 2024-05-11
3221 Human Substantia Nigra Neurons Encode Reward Expectations
Imtiaz, Z.; Kato, A.; Kopell, B. H.; Qasim, S. E.; Davis, A. N.; Martinez, L. N.; Heflin, M.; Kulkarni, K. R.; Morsi, A.; Gu, X.; Saez, I.
10.1101/2024.05.10.593406 — neuroscience — Posted on 2024-05-11
3222 The large GTPase Guanylate-Binding Protein-1 (GBP-1) promotes mitochondrial fission in glioblastoma.
Kalb, R. C.; Nyabuto, G. O.; Morran, M. P.; Maity, S.; Justinger, J. S.; Nestor-Kalinosky, A. L.; Vestal, D. J.
10.1101/2024.05.08.593235 — cancer biology — Posted on 2024-05-10
3223 Single-Cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape
Song, L.; Li, Q.; Xia, L.; Sahay, A.; Qiu, Q.; Li, Y.; Li, H.; Sasaki, K.; Susztak, K.; Wu, H.; Wan, L.
10.1101/2024.05.09.591709 — cancer biology — Posted on 2024-05-10
3224 Senescent cell extracellular vesicles are critical elements restricting cancer recurrence
Ziglari, T.; Calistri, N.; Derrick, D.; Nakayasu, E. S.; Burnet, M.; Kyle, J. E.; Hoare, M. W.; Heiser, L.; Pucci, F.
10.1101/2022.06.30.498366 — cancer biology — Posted on 2024-05-10
3225 Resolving sulfation PTMs on a plant peptide hormone using nanopore sequencing
Chen, X.; van de Sande, J. W.; Ritmejeris, J.; Wen, C.; Brinkerhoff, H.; Laszlo, A. H.; Albada, B.; Dekker, C.
10.1101/2024.05.08.593138 — biophysics — Posted on 2024-05-10
3226 Key role of P230 in the hinge region on the IgG architecture and function
Koseki, Y.; Yamaguchi, Y.; Aoyama, M.; Tada, M.; Senoo, A.; Ishii-Watabe, A.; Uchihashi, T.; Uchiyama, S.; Kato, K.; Yanaka, S.; Caaveiro, J. M. M.
10.1101/2024.05.10.593077 — biophysics — Posted on 2024-05-10
3231 Imaging the extracellular matrix in live tissues and organisms with a glycan-binding fluorophore
Fiore, A.; Yu, G.; Northey, J. J.; Patel, R.; Ravenscroft, T. A.; Ikegami, R.; Kolkman, W.; Kumar, P.; Grimm, J. B.; Dilan, T. L.; Ruetten, V. M. S.; Ahrens, M. B.; Shroff, H.; Lavis, L. D.; Wang, S.; Weaver, V. M.; Pedram, K.
10.1101/2024.05.09.593460 — biochemistry — Posted on 2024-05-10
3232 Identification of novel bone-resorption markers by osteoclasts in vitro and in vivo
Norman, B. P.; Dillon, J. P.; Alkharabsheh, S. M.; Wilson, P. J.; Davison, A. S.; Chapman, E.; Baker, J.; Coyle, S.; Probert, C. S.; Ranganath, L. R.; Gallagher, J. A.
10.1101/2024.05.10.593489 — biochemistry — Posted on 2024-05-10
3234 Enhancing Transcriptome Mapping with Rapid PRO-seq Profiling of Nascent RNA
Cingaram, P. R.; Beckedorff, F.; Yue, J.; Liu, F.; Gomes Dos Santos, H.; Shiekhattar, R.
10.1101/2024.05.08.593182 — molecular biology — Posted on 2024-05-10
3235 Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant
Ahmed, Y.; Nguyen, B. A.; Afrin, S.; Singh, V.; Evers, B.; Singh, P.; Pedretti, R.; Wang, L.; Bassett, P.; Fernandez-Ramirez, M. d. C.; Pekala, M.; Kluve-Beckerman, B.; Saelices Gomez, L.
10.1101/2024.05.09.593396 — molecular biology — Posted on 2024-05-10
3236 Mitochondrial Phosphopantetheinylation is Required for Oxidative Function
Norden, P. R.; Wedan, R. J.; Longenecker, J. Z.; Preston, S. E. J.; Graber, N.; Ols, O.; Canfield, M.; McLaughlin, E.; Nowinski, S. M.
10.1101/2024.05.09.592977 — molecular biology — Posted on 2024-05-10
3237 Mammalian RNAi represses pericentromeric lncRNAs to maintain genome stability
Sandoval, R.; Dilsavor, C. N.; Grishanina, N. R.; Patel, V.; Zamudio, J. R.
10.1101/2024.05.09.593425 — molecular biology — Posted on 2024-05-10
3238 Nascent dendrite branches initiated by a localized burst of Spire-dependent actin polymerization.
Hatton, D.; Marquilly, C.; Hanrahan, C.; Ferreira, T. A.; Ou, Y.; Cinq-mars, L.; Silkworth, W.; Bailey, H. M.; Quinlan, M.; van Meyel, D. J.
10.1101/2022.06.16.496481 — neuroscience — Posted on 2024-05-11
3241 Disparate requirements for RAD54L in replication fork reversal
Uhrig, M. E.; Sharma, N.; Maxwell, P.; Selemenakis, P.; Mazin, A. V.; Wiese, C.
10.1101/2023.07.26.550704 — cell biology — Posted on 2024-05-10
3244 A versatile bacterial innate immunity protein directly senses two disparate phage proteins
Zhang, T.; Cepauskas, A.; Nadieina, A.; Thureau, A.; Coppieters 't Wallant, K.; Martens, C.; Lim, D. C.; Garcia-Pino, A.; Laub, M. T.
10.1101/2024.05.10.593582 — microbiology — Posted on 2024-05-10
3245 Seasonal recurrence and modular assembly of an Arctic pelagic marine microbiome
Priest, T.; Oldenburg, E.; Popa, O.; Dede, B.; Metfies, K.; von Appen, W.-J.; Torres-Valdes, S.; Bienhold, C.; Fuchs, B. M.; Amann, R.; Boetius, A.; Wietz, M.
10.1101/2024.05.10.593482 — microbiology — Posted on 2024-05-10
3246 A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin.
Singh, M. K.; Bonnell, V.; Silva, I.; Santiago, V. F.; Moraes, M.; Adderley, J.; Doerig, C.; Palmisano, G.; Llinas, M.; Garcia, C. R.
10.1101/2023.09.11.557196 — microbiology — Posted on 2024-05-10
3247 Cell-free assays reveal the HIV-1 capsid protects reverse transcripts from cGAS
Scott, T. M.; Arnold, L. M.; Powers, J. A.; McCann, D. A.; Christensen, D. E.; Pereira, M. J.; Zhou, W.; Torrez, R. M.; Iwasa, J. H.; Kranzusch, P. J.; Sundquist, W. I.; Johnson, J. S.
10.1101/2024.04.22.590513 — microbiology — Posted on 2024-05-10
3249 Neuroanatomical changes observed over the course of a human pregnancy
Pritschet, L.; Taylor, C. M.; Cossio, D.; Santander, T.; Grotzinger, H.; Faskowitz, J.; Handwerker, D. A.; Layher, E.; Chrastil, E. R.; Jacobs, E. G.
10.1101/2023.12.14.571688 — neuroscience — Posted on 2024-05-10
3253 Systematic Development of Reprogrammed Modular Integrases Enables Precise Genomic Integration of Large DNA Sequences
Fauser, F.; Arangundy-Franklin, S.; Davis, J. E.; Liu, L.; Schmidt, N. J.; Rodriguez, L.; Scarlott, N. A.; Mureli, R.; Xia, D. F.; Hinkley, S. J.; Kadam, B. N.; Nguyen, N.; Lam, S.; Bourgeois, B.; Tait, E.; Qasim, M.; Vaidya, V.; Chen, A.; Nguyen, A.; Li, P.; Paschon, D. E.; Davis, G. D.; Miller, J. C.
10.1101/2024.05.09.593242 — synthetic biology — Posted on 2024-05-10
3256 mRNA psi profiling using nanopore DRS reveals cell-type-specific pseudouridylation
McCormick, C. A.; Qiu, Y.; Fanari, O.; Liu, Y.; Bloch, D.; Klink, I. N.; Meseonznik, M.; Jain, M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2024.05.08.593203 — genomics — Posted on 2024-05-10
3257 High-throughput protein characterization by complementation using DNA barcoded fragment libraries
Biggs, B. W.; Price, M. N.; Lai, D.; Escobedo, J.; Fortanel, L.; Huang, Y. Y.; Kim, K.; Trotter, V. V.; Kuehl, J. V.; Lui, L. M.; Chakraborty, R.; Deutschbauer, A. M.; Arkin, A. P.
10.1101/2024.05.08.593210 — genomics — Posted on 2024-05-10
3258 De novo genome assembly for an endangered lemur using portable nanopore sequencing in rural Madagascar
Hauff, L. R.; Rasoanaivo, N. E.; Razafindrakoto, A.; Ravelonjanahary, H.; Wright, P. C.; Rakotoarivony, R.; Bergey, C. M.
10.1101/2024.05.09.591673 — genomics — Posted on 2024-05-10
3259 Unraveling Morphogenesis, Starvation, and Light Responses in a Mushroom-Forming Fungus, Coprinopsis cinerea, Using Long Read Sequencing and Extensive Expression Profiling
Hegedüs, B.; Sahu, N.; Balint, B.; Haridas, S.; Bense, V.; Merenyi, Z.; Viragh, M.; Wu, H.; Liu, X.-B.; Riley, R.; Lipzen, A.; Koriabine, M.; Savage, E.; Guo, J.; Barry, K.; Ng, V.; Urban, P.; Gyenesei, A.; Freitag, M.; Grigoriev, I. V.; Nagy, L. G.
10.1101/2024.05.10.593147 — genomics — Posted on 2024-05-10
3260 Investigating spatial dynamics in spatial omics data with StarTrail
Chen, J.; Xiong, C.; Sun, Q.; Wang, G. W.; Gupta, G. P.; Halder, A.; Li, Y.; Li, D.
10.1101/2024.05.08.593025 — genetics — Posted on 2024-05-10
3261 Closely related facultative and constitutive CAM phenotypes show little transcriptomic overlap in the subgenus Tillandsia
Groot Crego, C.; Saadain, S.; de La Harpe, M.; Hess, J.; Barfuss, M. H. J.; Till, W.; Lexer, C.; Paun, O.
10.1101/2024.05.09.593278 — evolutionary biology — Posted on 2024-05-10
3267 Linear ubiquitin chains remodel the proteome and influence the levels of hundreds of regulators in Drosophila
Nuga, O.; Richardson, K.; Patel, N. C.; Wang, X.; Pagala, V.; Stephan, A.; Peng, J.; Demontis, F.; Todi, S. V.
10.1101/2024.05.09.593206 — cell biology — Posted on 2024-05-10
3268 UPF1 is required for gene expression in mitochondria and for the elimination of paternal mtDNA
Wright, M. T.; Singh, A. K.; Dixon, H. L.; Price, E. M.; Connolly, E. C.; di Maio, A.; Barlow, J. P.; Catoni, M.; Fan, Y.; Brogna, S.
10.1101/2024.05.10.591322 — cell biology — Posted on 2024-05-10
3269 Microbiome Modulation Uncouples Efficacy and Toxicity Induced by Programmed Death-1/Programmed Death-Ligand1 Blockade
Cogrossi, L. L.; Zordan, P.; Grioni, M.; Tosi, A.; Rizzo, N.; Policastro, A.; Mattorre, B.; Lorenzoni, M.; Meregalli, G.; Sisti, S.; Sanvito, F.; Chesi, M.; Bergsagel, L.; Clementi, N.; Rosato, A.; Bellone, M.
10.1101/2024.05.08.590282 — immunology — Posted on 2024-05-10
3270 Origins and diversity of pan-isotype human bone marrow plasma cells
Pacheco, G. A.; Rao, V.; Yoo, D. K.; Saghaei, S.; Tong, P.; Kumar, S.; Marini-Rapoport, O.; Allahyari, Z.; Moghaddam, A. S.; Esbati, R.; Alirezaee, A.; Parnes, A.; Patil, S. U.; Wesemann, D. R.
10.1101/2024.05.08.592267 — immunology — Posted on 2024-05-10
3272 Proinsulin C-peptide is a major source of HLA-DQ8 restricted HIPs recognized by human Islet-Infiltrating CD4+ T cells
Bhattacharjee, P.; Pakusch, M.; Lacorcia, M.; Tresoldi, E.; Rubin, A. F.; Foster, A.; King, L. S.; Chiu, C.; Kay, T.; Karas, J. A.; Cameron, F. J.; Mannering, S. I.
10.1101/2024.05.09.593303 — immunology — Posted on 2024-05-10
3274 Molecular mechanism of plasmid elimination by the DdmDE defense system
Loeff, L.; Adams, D. W.; Chanez, C.; Stutzmann, S.; Righi, L.; Blokesch, M.; Jinek, M.
10.1101/2024.05.10.593530 — microbiology — Posted on 2024-05-10
3275 Laboratory in vitro replication of Ostreid Herpes Virus (OsHV-1) using Pacific oyster tissue explants
Potts, R. W. A.; Regan, T.; Ross, S.; Bateman, K.; Hooper, C.; Paley, R.; Houston, R. D.; Bean, T. P.
10.1101/2024.05.10.593497 — microbiology — Posted on 2024-05-10
3278 Spatial Transcriptomic Sequencing of a DIPG-infiltrated Brainstem reveals Key Invasion Markers and Novel Ligand-Receptor Pairs contributing to Tumour to TME Crosstalk
Kordowski, A.; Mulay, O.; Tan, X.; Vo, T.; Baumgartner, U.; Maybury, M. K.; Hassall, T. E. G.; Wainwright, B.; Harris, L.; Nguyen, Q.; Day, B. W.
10.1101/2024.05.07.593050 — cancer biology — Posted on 2024-05-10
3279 Single cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization.
Liu, F.; Ding, Y.; Xu, Z.; Hao, X.; Pan, T.; Miles, G.; Rivas, C. H.; Hoffman, D.; Edwards, D. G.; Chen, E.; Wang, H.; Chan, H. L.; Liu, J.; Wu, L.; Yu, L.; Gao, Y.; Dominguez, L. B.; Dieffenbach, M. W.; Aguirre, S.; Zhang, W.; Chen, X.; Wu, Y.-H.; Shen, Y.; Bado, I. L.; Gugala, Z.; Satcher, R. L.; Zhang, X.
10.1101/2024.05.07.593027 — cancer biology — Posted on 2024-05-10
3280 A single cell framework identifies functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis
Ediriwickrema, A.; Nakauchi, Y.; Fan, A.; Köhnke, T.; Hu, X.; Luca, B. A.; Kim, Y.; Ramakrishnan, S.; Nakamoto, M.; Karigane, D.; Linde, M. H.; Azizi, A.; Newman, A. M.; Gentles, A. J.; Majeti, R.
10.1101/2024.05.07.592983 — cancer biology — Posted on 2024-05-10
3281 Targeting protein tyrosine phosphatase non-receptor type 2 with a novel inhibitor for AML therapy
Kuang, W.; Jiang, J.; Wang, X.; Wang, D.; Ji, M.; Zhu, Y.; Yuan, K.; Ding, J.; Wang, W.; Song, M.; Min, W.; Huang, F.; Wang, L.; Gu, W.; Hao, H.; Xiao, Y.; Yang, P.
10.1101/2024.05.07.592940 — cancer biology — Posted on 2024-05-10
3284 Characterization of a Biochemical Mouse Model of Primary Aldosteronism for Thermal Therapies
Keck, S. A.; Mullen, N.; Taylor, A. E.; Gliligan, L. C.; Pyle, M.; Shrestha, T. B.; Sebek, J.; Highland, M. A.; Challapalli, R.; Arlt, W.; Bossmann, S. H.; Dennedy, M. C.; Prakash, P.; Basel, M. T.
10.1101/2024.05.07.592955 — cancer biology — Posted on 2024-05-10
3286 Unveiling genetic anchors in Saccharomyces cerevisiae: QTL mapping identifies IRA2 as a key player in ethanol tolerance and beyond
Tristao, L. E.; de Souza, L. I. S.; Vargas, B. d. O.; Jose, J.; Carazzolle, M. F.; Silva, E. M.; Gualhardo, J. P.; Pereira, G. A. G.; de Mello, F. d. S. B.
10.1101/2024.05.08.593158 — genetics — Posted on 2024-05-10
3287 Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines
Crombie, T. A.; Rajaei, M.; Saxena, A. S.; Johnson, L. M.; Saber, S.; Tanny, R. E.; Ponciano, J. M.; Andersen, E. C.; Zhou, J.; Baer, C. F.
10.1101/2024.05.08.593038 — evolutionary biology — Posted on 2024-05-10
3288 Developmental alterations of indirect-pathway medium spiny neurons in mouse models of Huntington's disease.
Lebouc, M.; Bonamy, L.; Scharnholz, J.; Richard, Q.; Courtand, G.; Baufreton, J. M.; Garret, M.
10.1101/2024.05.10.593545 — neuroscience — Posted on 2024-05-10
3290 Advancing chloroplast synthetic biology through high-throughput plastome engineering of Chlamydomonas reinhardtii
Inckemann, R.; Chotel, T.; Brinkmann, C. K.; Burgis, M.; Andreas, L.; Baumann, J.; Sharma, P.; Klose, M.; Barret, J.; Ries, F.; Paczia, N.; Glatter, T.; Mackinder, L.; Willmund, F.; Erb, T. J.
10.1101/2024.05.08.593163 — synthetic biology — Posted on 2024-05-10
3292 A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins
Grosskopf, J. D.; Sidabras, J. W.; Altenbach, C.; Anderson, J. R.; Mett, R. R.; Strangeway, R. A.; Hyde, J. S.; Hubbell, W. L.; Lerch, M. T.
10.1101/2024.05.07.593074 — biophysics — Posted on 2024-05-10
3295 Interplay of condensate material properties and chromatin heterogeneity governs nuclear condensate ripening
Banerjee, D. S.; Chigumira, T.; Lackner, R. M.; Kratz, J. C.; Chenoweth, D. M.; Banerjee, S.; Zhang, H.
10.1101/2024.05.07.593010 — biophysics — Posted on 2024-05-10
3297 Drosophila glue evolved different adhesive and mechanical properties across 50 million years
Monier, M.; Lorenzi, J.-N.; Narasimha, S.; Borne, F.; Contremoulins, V.; Mevel, L.; Petit, R.; Graner, F.; Courtier-Orgogozo, V.
10.1101/2024.05.08.593221 — biophysics — Posted on 2024-05-10
3301 Revisiting typing systems for group B Streptococcus (GBS) prophages: an application in prophage detection and classification in GBS isolates from Argentina
Kovacec, V.; Di Gregorio, S.; Pajon, M.; Crestani, C.; Poklepovich, T.; Campos, J.; Basit Khan, U.; Bentley, S. D.; Jamrozy, D.; Mollerach, M.; Bonofiglio, L.
10.1101/2024.05.08.593127 — bioinformatics — Posted on 2024-05-10
3307 Extensive folding variability between homologous chromosomes in mammalian cells
Irastorza-Azcarate, I.; Kukalev, A.; Kempfer, R.; Thieme, C. J.; Mastrobuoni, G.; Markowski, J.; Loof, G.; Sparks, T. M.; Brookes, E.; Natarajan, K. N.; Sauer, S.; Fisher, A. G.; Nicodemi, M.; Ren, B.; Schwarz, R. F.; Kempa, S.; Pombo, A.
10.1101/2024.05.08.591087 — genomics — Posted on 2024-05-10
3308 Genome assembly of the southern pine beetle (Dendroctonus frontalis Zimmerman) reveal the origins of gene content reduction in Dendroctonus
Copeland, M.; Landa, S.; Owoyemi, A.; Jonika, M. M.; Alfieri, J.; Sylvester, T.; Hoover, Z.; Hjelmen, C. E.; Johnston, J. S.; Kyre, B. R.; Rieske, L. K.; Blackmon, H.; Casola, C.
10.1101/2024.05.08.592785 — genomics — Posted on 2024-05-10
3312 Fuel buildup shapes post-fire fuel decomposition through soil heating effects on plants, fungi, and soil chemistry
Hopkins, J. R.; Semenova-Nelsen, T. A.; Huffman, J. M.; Jones, N. J.; Robertson, K. M.; Platt, W. J.; Sikes, B. A.
10.1101/2024.05.08.592975 — ecology — Posted on 2024-05-10
3314 Barcoding Notch signaling in the developing brain
Siniscalco, A.; Perera, R. P.; Greenslade, J. E.; Masters, A.; Doll, H. M.; Raj, B.
10.1101/2024.05.10.593533 — developmental biology — Posted on 2024-05-10
3315 High Throughput Screening with a Primary Human Mucociliary Airway Model Identifies a Small Molecule with Anti-SARS-CoV-2 Activity
Sen, C.; Rickabaugh, T. M.; Jeyachandran, A. V.; Yuen, C.; Ghannam, M.; Durra, A.; Aziz, A.; Castillo, K.; Garcia, G.; Purkayastha, A.; Han, B.; Boulton, F. W.; Chekler, E.; Garces, R.; Wolff, K. C.; Riva, L.; Kirkpatrick, M. G.; Gebara-Lamb, A.; McNamara, C. W.; Betz, U.; Arumugaswami, V.; Damoiseaux, R.; Gomperts, B.
10.1101/2024.05.09.593388 — cell biology — Posted on 2024-05-10
3316 "What" and "when" predictions jointly modulate speech processing
Auksztulewicz, R.; Ödül, O. B.; Helbling, S.; Böke, A.; Cappotto, D.; Luo, D.; Schnupp, J.; Melloni, L.
10.1101/2024.05.10.593519 — neuroscience — Posted on 2024-05-10
3317 Near infrared fluorescent nanosensors for high spatiotemporal oxytocin imaging
Adams, J.; Komatsu, N.; Navarro, N. P.; Leem, E.; Sun, X.; Zhao, J.; Arias-Soto, O.; Landry, M.
10.1101/2024.05.10.593556 — neuroscience — Posted on 2024-05-10
3322 Hydrogels for Local and Sustained Delivery of Bacteriophages to Treat Multidrug-Resistant Wound Infections
Lin, Y.-H.; Dharmaraj, T.; Chen, Q.; Echterhof, A.; Manasherob, R.; Zheng, L. J.; de Leeuw, C.; Peterson, N. A.; Stannard, W.; Li, Z.; Hajfathalian, M.; Hargil, A.; Martinez, H. A.; Chang, T. H. W.; Blankenberg, F. B.; Amanatullah, D.; Chaudhuri, O.; Bollyky, P.
10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-05-10
3323 Gekko gecko as a model organism for understanding aspects of laryngeal vocal evolution
Gutjahr, R.; Kever, L.; Jonsson, T.; Talamantes Ontiveros, D.; Chagnaud, B. P.; Herrel, A.
10.1101/2024.05.10.593509 — animal behavior and cognition — Posted on 2024-05-10
3324 Recovery mode: Marine protected areas enhance the resilience of kelp species from marine heatwaves
Olguin-Jacobson, C.; Arafeh-Dalmau, N.; Early-Capistran, M. M.; Espinoza-Montes, J. A.; Hernandez-Velasco, A.; Martinez, R.; Romero, A.; Torre, J.; Woodson, C. B.; Micheli, F.
10.1101/2024.05.08.592820 — ecology — Posted on 2024-05-10
3326 Circulating tumor cell characterization and classification by novel combinatorial dual-color (CoDuCo) in situ hybridization and supervised machine learning
Bonstingl, L.; Zinnegger, M.; Sallinger, K.; Pankratz, K.; Pritz, E.; Odar, C.; Skofler, C.; Ulz, C.; Oberauner-Wappis, L.; Borras-Cherrier, A.; Somođi, V.; Heitzer, E.; Kroneis, T.; Bauernhofer, T.; El-Heliebi, A.
10.1101/2024.05.08.592946 — molecular biology — Posted on 2024-05-10
3327 Quinolinic acid links kidney injury to brain toxicity
Saliba, A.; Debnath, S.; Tamayo, I.; Tumova, J.; Maddox, M.; Singh, P.; Fastenau, C.; Maity, S.; Lee, H. J.; Zhang, G.; Hejazi, L.; O'Connor, J.; Fongang, B.; Hopp, S. C.; Bieniek, K. F.; Lechleiter, J. D.; Sharma, K.
10.1101/2024.05.07.592801 — molecular biology — Posted on 2024-05-10
3328 Two-photon voltage imaging with rhodopsin-based sensors
Grimm, C.; Sims, R. R.; Tanese, D.; Mohamed Lafirdeen, A. S.; Chan, C. Y.; Faini, G.; Putti, E.; Del Bene, F.; Papagiakoumou, E.; Emiliani, V.
10.1101/2024.05.10.593541 — neuroscience — Posted on 2024-05-10
3330 EVIDENCE OF SPATIAL PERIODIC FIRING IN THE SUBICULUM OF MICE
Abad Perez, P.; Martinez-Otero, L. M.; Borrell, V.; Brotons, J. R.
10.1101/2024.05.10.593498 — neuroscience — Posted on 2024-05-10
3331 Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice
Yadav-Samudrala, B. J.; Dodson, H.; Ramineni, S.; Kim, E.; Poklis, J. L.; Lu, D.; Ignatowska-Jankowska, B. M.; Lichtman, A. H.; Fitting, S.
10.1101/2024.05.10.593514 — neuroscience — Posted on 2024-05-10
3332 25-hydroxycholesterol dysregulates brain endothelial cell function and exacerbates cerebral haemorrhage
Tapia, V. S.; Withers, S. E.; Zhou, R.; Bennington, A.; Hedley, F.; El Khouja, A.; Luka, N.; Massimo, M.; Crilly, S.; Long, K. R.; Lawrence, C. B.; Kasher, P. R.
10.1101/2024.05.10.590792 — neuroscience — Posted on 2024-05-10
3334 Connecting the Dots: Approaching a Standardized Nomenclature for Molecular Connectivity Combining Data and Literature
Reed, M. B.; Cocchi, L.; Knudsen, G. M.; Sander, C.; Gryglewski, G.; Chen, J.; Volpi, T.; Fisher, P.; Khattar, N.; Silberbauer, L. R.; Murgas, M.; Godbersen, G. M.; Nics, L.; Walter, M.; Hacker, M.; Hammers, A.; Ogden, T. R.; Mann, J. J.; Biswal, B.; Rosen, B.; Carson, R.; Price, J.; Lanzenberger, R.; Hahn, A.
10.1101/2024.05.10.593490 — neuroscience — Posted on 2024-05-10
3340 Emerging neurodevelopmental mechanisms in patient induced pluripotent stem cells-derived spheroids modelling SCN1A Dravet Syndrome
Mattei, C.; Mao, M.; Byars, S.; Mohamed Syazwan, E.; Oliva, M.; Karle, T.; Richards, K.; Scheffer, I.; Petrou, S.; Maljevic, S.
10.1101/2024.05.09.593441 — neuroscience — Posted on 2024-05-10
3341 Neuropeptide Y co-opts neuronal ensembles for memory lability and stability
Wu, Y.-J.; Gu, X.; Kong, Y.; Yang, S.; Wang, H.; Xu, M.; Wang, Q.; Yi, X.; Lin, Z.-J.; Jiao, Z.-H.; Cheung, H.; Zhao, X.-Y.; Bian, X.; Jiang, Q.; Li, Y.; Zhu, M. X.; Wang, L.-Y.; Li, Y.; Huang, J.; Li, Q.; Li, W.-G.; Xu, T.-L.
10.1101/2024.05.09.593455 — neuroscience — Posted on 2024-05-10
3344 Intracranial substrates of meditation-induced neuromodulation in amygdala and hippocampus
Maher, C.; Tortolero, L.; Cummins, D.; Saad, A.; Young, J. J.; Nunez Martinez, L.; Schulman, Z.; Marcuse, L.; Waters, A.; Mayberg, H.; Davidson, R. J.; Saez, I.; Panov, F.
10.1101/2024.05.10.593445 — neuroscience — Posted on 2024-05-10
3346 Brassinosteroids function as the plant male and female reproductive hormone coordinating gene expression.
Matsuura-Tokita, K.; Suzuki, T.; Kimata, Y.; Takebayashi, Y.; Ueda, M.; Nakano, T.; Sakakibara, H.; Nakano, A.; Higashiyama, T.
10.1101/2024.05.07.592278 — plant biology — Posted on 2024-05-10
3349 Effect Of Ayahuasca on Experimental Models of Ethanol Addiction and Immunohistochemistry Analysis in Rodents
Distefano Wiltenburg, V.; Morales-Lima, G.; Sousa Santos, A. V.; Echeverry Bermudez, M.; Cardoso Cruz, F.; de Oliveira Silveira, G.; Yonamine, M.; Ayako Tiba, P.; Rieli Mendes, F.
10.1101/2024.05.07.592962 — pharmacology and toxicology — Posted on 2024-05-10
3350 KF4 anti-CELA1 Antibody and Purified α1-Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine α1-Antitrypsin Deficiency
Devine, A. J.; Smith, N. J.; Joshi, R.; Brooks-Patton, B.; Dunham, J.; Varisco, A. N.; Goodman, E. M.; Fan, Q.; Zingarelli, B.; Varisco, B. M.
10.1101/2024.05.07.592994 — pathology — Posted on 2024-05-10
3352 Real-time monitoring of attenuated cytomegalovirus using Raman spectroscopy allows non-destructive characterization during flow
Athalye, S. M.; Maruthamuthu, M. K.; Esmaili, E.; Boodaghidizaji, M.; Raffaele, J.; Selvamani, V.; Smith, J. P.; Matos, T.; Rustandi, R.; Ardekani, A.; Verma, M. S.
10.1101/2024.05.08.593031 — bioengineering — Posted on 2024-05-10
3353 Embryo spatial 3D genomics
Ma, Y.; Gou, B.; Xu, Y.; Shu, M.; Lu, F.; Li, X.
10.1101/2024.05.07.592900 — genetics — Posted on 2024-05-10
3358 Activation loop phosphorylation of Cdk11 is restrained by PNUTS-PP1 and regulates Cdk11 activity and function
Campbell, A. E.; Aljabri, A. A.; Hesketh, A.; Byrne, D. P.; Bennett, H.; Patel, S.; Brownridge, P.; Zacharchenko, T.; Bucca, G.; Eyers, P. A.; Betancourt, A. J.; Eyers, C. E.; Bennett, D.
10.1101/2024.05.08.592654 — molecular biology — Posted on 2024-05-10
3359 Thetis cells induce food-specific Treg cell differentiation and oral tolerance
Parisotto, Y.; Cabric, V.; Park, T.; Akagbosu, B.; Zhao, Z.; Lo, Y.; Fisher, L.; Shibu, G.; Paucar Iza, Y.; Leslie, C.; Brown, C.
10.1101/2024.05.08.592952 — immunology — Posted on 2024-05-10
3361 Neuron Derived Cytokine Interleukin-34 Controls Developmental Microglia Function
Devlin, B.; Nguyen, D.; Grullon, G.; Clark, M.; Ceasrine, A. M.; Deja, M.; Shah, A.; Ati, S.; Finn, A.; Ribeiro, D.; Schaefer, A.; Bilbo, S. D.
10.1101/2024.05.10.589920 — neuroscience — Posted on 2024-05-10
3362 Task-specific topographical maps of neural activity in the primate lateral prefrontal cortex
Xiang, J. D.; Roussy, M.; Corrigan, B.; Gulli, R. A.; Luna, R.; Mofrad, M. H.; Muller, L.; Diedrichsen, J.; Schmitz, T. W.; Martinez-Trujillo, J.; Mur, M.
10.1101/2024.05.10.591729 — neuroscience — Posted on 2024-05-10
3365 Accurate single domain scaffolding of three non-overlapping protein epitopes using deep learning
Castro, K. M.; Watson, J. L.; Wang, J.; Southern, J.; Ayardulabi, R.; Georgeon, S.; Rosset, S.; Baker, D.; Correia, B. E.
10.1101/2024.05.07.592871 — bioengineering — Posted on 2024-05-10
3366 Accelerated growth increases the somatic epimutation rate in trees
Zhou, M.; Schmied, G.; Bradatsch, M.; Resente, G. A.; Hazarika, R. R.; Kakoulidou, I.; Costa, M.; Serra, M.; Uhl, E.; Schmitz, R. J.; Hilmers, T.; Caicoya, A. T.; Crivellaro, A.; Pretzsch, H.; Johannes, F.
10.1101/2024.05.07.592680 — genomics — Posted on 2024-05-10
3368 Super Enhancer-driven LncRNA UNC5B-AS1 Inhibits Inflammatory Phenotypic Transition in Smooth Muscle Cells via Lactylation Modification
Zhu, X.; Pang, X.; Wang, X.; Guan, X.; Wang, Z.; Zhang, L.; Zheng, X.; Li, F.; Mei, J.; Ou, L.; Liu, Y.; Meng, Z.; Chen, Y.; Ma, C.
10.1101/2024.05.07.593065 — molecular biology — Posted on 2024-05-10
3371 Neuronal interactions in forebrain organoids lead to protective antiviral responses
Negatu, S. G.; Vazquez, C.; Bannerman, C.; Amses, K. R.; Ming, G.-L.; Jurado, K. A.
10.1101/2024.05.07.592842 — immunology — Posted on 2024-05-10
3373 Inferring the composition of the blood plasma proteome by a human proteome distribution atlas
Malmstrom, E.; Hauri, S.; Mohanty, T.; Scott, A. M.; Karlsson, C. A. Q.; Gueto Tettay, C. A.; Ahrman, E.; Nozohoor, S.; Tingstedt, B.; Regner, S.; Elfving, P.; Bjermer, L.; Forsvall, A.; Doyle, A.; Magnusson, M.; Hedenfalk, I.; Kannisto, P.; Brandt, C.; Nilsson, E.; Dahlin, L. B.; Malm, J.; Linder, A.; Malmstrom, L.; Nimeus, E.; Malmstrom, J.
10.1101/2024.05.07.592979 — systems biology — Posted on 2024-05-10
3375 FAPM: Functional Annotation of Proteins using Multi-Modal Models Beyond Structural Modeling
Xiang, W.; Xiong, Z.; Huan, C.; Xiong, J.; Zhang, W.; Fu, Z.; Zheng, M.; Liu, B.; Shi, Q.
10.1101/2024.05.07.593067 — bioinformatics — Posted on 2024-05-10
3379 Clinicogenomic characterization of inflammatory breast cancer
Priedigkeit, N.; Harrison, B.; Shue, R.; Hughes, M. E.; Li, Y.; Kirkner, G. J.; Spurr, L. F.; Remolano, M. C.; Strauss, S.; Files, J.; Feeney, A.-M.; Grant, L.; Mohammed-Abreu, A.; Garrido-Castro, A.; Sousa, R. B.; Bychkovsky, B.; Nakhlis, F.; Bellon, J. R.; King, T. A.; Winer, E. P.; Lindeman, N.; Johnson, B. E.; Sholl, L.; Dillon, D.; Overmoyer, B.; Tolaney, S. M.; Cherniack, A.; Lin, N. U.; Lynce, F.
10.1101/2024.05.07.592972 — genomics — Posted on 2024-05-10
3380 Shadows over Caribbean reefs: Identification of a new invasive soft coral species, Xenia umbellata, in southwest Puerto Rico
Toledo-Rodriguez, D. A.; Veglia, A. J.; Jimenez-Marrero, N. M.; Gomez-Samot, J. M.; McFadden, C. S.; Weil, E. F.; Schizas, N. V.
10.1101/2024.05.07.592775 — genetics — Posted on 2024-05-10
3383 Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
Tenthorey, J.; del Banco, S.; Ramzan, I.; Klingenberg, H.; Liu, C.; Emerman, M.; Malik, H. S.
10.1101/2024.05.07.592993 — evolutionary biology — Posted on 2024-05-10
3384 Mouse embryonic stem cells require sustained DNMT1-mediated DNA methylation maintenance for epigenomic, genomic and functional integrity
Elder, E.; Lemieux, A.; Legault, L.-M.; Caron, M.; Bertrand-Lehouillier, V.; Dupas, T.; Raynal, N.; Bourque, G.; Sinnett, D.; Gevry, N.; McGraw, S.
10.1101/2024.05.07.592204 — cell biology — Posted on 2024-05-10
3385 Compartmental Differences in the Retinal Ganglion Cell Mitochondrial Proteome
Lewis, L. S.; Skiba, N. P.; Hao, Y.; Bomze, H. M.; Arshavsky, V. Y.; Cartoni, R.; Gospe, S. M.
10.1101/2024.05.07.593032 — cell biology — Posted on 2024-05-10
3387 A regulatory gene network that couples floral transition to shoot apical meristem morphology in Arabidopsis
Bertran Garcia de Olalla, E.; Rodriguez-Maroto, G.; Cerise, M.; Vayssieres, A.; Severing, E.; Lopez-Sampere, Y.; Wang, K.; Schaefer, S.; Formosa-Jordan, P.; Coupland, G.
10.1101/2024.05.10.593152 — plant biology — Posted on 2024-05-10
3390 Modulation of Ideonella sakaiensis PETase active site flexibility and activity on morphologically distinct substrates by surface charge engineering
Ding, K.; Levitskaya, Z.; Sana, B.; Pasula, R. R.; Kannan, S.; Adam, A.; Sundaravadanam, V. V.; Verma, C.; Lim, S.; Ghadessy, J. F.
10.1101/2024.05.07.589851 — bioengineering — Posted on 2024-05-10
3393 RESOLVING BIOLOGY'S DARK MATTER: SPECIES RICHNESS, SPATIOTEMPORAL DISTRIBUTION, AND COMMUNITY COMPOSITION OF A DARK TAXON
Hartop, E.; Lee, L.; Srivathsan, A.; Jones, M.; de la Pena Aguilera, P.; Ovaskainen, O.; Roslin, T.; Meier, R.
10.1101/2024.05.07.592951 — ecology — Posted on 2024-05-10
3398 Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin-deficient muscle
Laitila, J.; Seaborne, R.; Ranu, N.; Kolb, J.; Wallgren-Pettersson, C.; Witting, N.; Vissing, J.; Vilchez, J. J.; Zanoteli, E.; Palmio, J.; Huovinen, S.; Granzier, H.; Ochala, J.
10.1101/2024.05.07.592906 — physiology — Posted on 2024-05-10
3399 BUB1 regulates non-homologous end joining pathway to mediate radioresistance in triple-negative breast cancer
Sriramulu, S.; Thoidingjam, S.; Chen, W.-M.; Hassan, O.; Siddiqui, F.; Brown, S. L.; Movsas, B.; Green, M. D.; Davis, A. J.; Speers, C.; Walker, E.; Nyati, S.
10.1101/2024.05.07.592812 — cancer biology — Posted on 2024-05-10
3400 Unbiased metastatic niche-labeling identifies estrogen receptor-positive macrophages as a barrier of T cell infiltration during bone colonization
Xu, Z.; Liu, F.; Ding, Y.; Pan, T.; Wu, Y.-H.; Liu, J.; Bado, I. L.; Zhang, W.; Wu, L.; Gao, Y.; Hao, X.; Yu, L.; Edwards, D. G.; Chan, H. L.; Aguirre, S.; Dieffenbach, M. W.; Chen, E.; Shen, Y.; Hoffman, D.; Dominguez, L. B.; Rivas, C. H.; Chen, X.; Wang, H.; Gugala, Z.; Satcher, R. L.; Zhang, X. H.- F.
10.1101/2024.05.07.593016 — cancer biology — Posted on 2024-05-10
3403 Mechanistic modeling of Mycobacterium tuberculosis β-carbonic anhydrase inhibitors using integrated systems biology and the QSAR approach
Bhowmik, R.; Manaithiya, A.; Parkkinen, J.; Kumar, S.; Mathew, B.; Parikka, M.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.
10.1101/2024.05.07.592909 — bioinformatics — Posted on 2024-05-10
3406 Intraplacental injection of human iPSC-derived PDX1+ pancreatic progenitors prolongs Pdx1-deficient mice survival
Wakimoto, A.; Jeon, H.; Shahri, Z. J.; Hayashi, T.; Liao, C.-W.; Gogoleva, N.; Suchy, F. P.; Noda, A.; An, Y.; Nakauchi, H.; Hayashi, Y.; Hamada, M.; Takahashi, S.
10.1101/2024.05.09.593461 — cell biology — Posted on 2024-05-10
3407 Biological aging of different blood cell types
Marttila, S.; Rajic, S.; Ciantar, J.; Mak, J. K.; Junttila, I. S.; Kummola, L.; Hägg, S.; Raitoharju, E.; Kananen, L.
10.1101/2024.05.07.592895 — molecular biology — Posted on 2024-05-10
3411 Interneuron loss and microglia activation by transcriptome analyses in the basal ganglia of Tourette syndrome
Wang, Y.; Fasching, L.; Wu, F.; Huttner, A.; Berretta, S.; Roberts, R.; Leckman, J. F.; Abyzov, A.; Vaccarino, F. M.
10.1101/2024.02.28.582504 — neuroscience — Posted on 2024-05-10
3412 KRas, in addition to Tp53 is a driver for early carcinogenesis and a molecular target in a mouse model of invasive gastro-esophageal adenocarcinoma
Anand, A.; Schoemig, L.; Lange, S.; Tran, L.; Flisikowski, K.; Oellinger, R.; Rad, R.; Vieth, M.; Steiger, K.; Baumeister, T.; Strangmann, J.; Alguel, H.; Ciecielski, K.; Boettcher, K.; Fang, H.-Y.; Carvalho, M.; Mohammad-Shahi, D.; Gerland, S.; Proano-Vasco, A.; Schnieke, A.; Thimme, R.; Schmid, R.; Wang, T. C.; Quante, M.
10.1101/2024.05.07.592904 — cancer biology — Posted on 2024-05-10
3417 Enhancing autophagy by redox regulation extends lifespan in Drosophila
Lennicke, C.; Bjedov, I.; Grönke, S.; Menger, K. E.; James, A. M.; Castillo-Quan, J. I.; van Leeuwen, L. A. G.; Foley, A.; Buricova, M.; Adcott, J.; Montoya, A.; Kramer, H. B.; Shliaha, P. V.; Logan, A.; Cabreiro, F.; Murphy, M. P.; Partridge, L.; Cocheme, H. M.
10.1101/790378 — molecular biology — Posted on 2024-05-10
3418 Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistance.
Prieto, A.; Miro, L.; Margolles, Y.; Bernabeu, M.; Salguero, D.; Merino, S.; Tomas, J.; Corbera, J. A.; Perez-Bosque, A.; Huttener, M.; Fernandez, L. A.; Juarez, A.
10.1101/2023.12.12.571265 — microbiology — Posted on 2024-05-10
3420 Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance
Lehtonen, H.; Jokela, H.; Hofmann, J. N.; Tola, L.; Mehmood, A.; Ginhoux, F.; Becher, B.; Greter, M.; Salmi, M.; Gerke, H.; Rantakari, P.
10.1101/2024.05.07.592305 — immunology — Posted on 2024-05-10
3421 Intratumoral administration of mRNA-1273 vaccine delays melanoma growth in mice
Boehm, D. T.; Landreth, K. M.; Sen-Kilic, E.; Lee, K. S.; Misra, B.; Bobbala, S.; Damron, F. H.; Liu, T. W.
10.1101/2024.05.06.592840 — immunology — Posted on 2024-05-10
3427 Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma
Curry, R. N.; Ma, Q.; McDonald, M. F.; Ko, Y.; Srivastava, S.; Chin, P.-S.; He, P.; Lozzi, B.; Jing, J.; Athukuri, P.; Wang, S.; Harmanci, A. O.; Arenkiel, B.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-05-10
3429 POLCAM: Instant molecular orientation microscopy for the life sciences
Bruggeman, E.; Zhang, O.; Needham, L.-M.; Koerbel, M.; Daly, S.; Cheetham, M.; Peters, R.; Wu, T.; Klymchenko, A. S.; Davis, S. J.; Paluch, E. K.; Klenerman, D.; Lew, M. D.; O'Holleran, K.; Lee, S. F.
10.1101/2023.02.07.527479 — biophysics — Posted on 2024-05-10
3433 AmpliconSuite: an end-to-end workflow for analyzing focal amplifications in cancer genomes
Luebeck, J.; Huang, E.; Kim, F.; Liefeld, T.; Dameracharla, B.; Ahuja, R.; Schreyer, D.; Prasad, G.; Adamaszek, M.; Kenkre, R.; Agashe, T.; Torvi, D.; Tabor, T.; Giurgiu, M.; Kim, S.; Kim, H.; Bailey, P.; Verhaak, R. G. W.; Deshpande, V. B.; Reich, M. M.; Mischel, P. S.; Mesirov, J.; Bafna, V.
10.1101/2024.05.06.592768 — bioinformatics — Posted on 2024-05-10
3434 Phasing millions of samples achieves near perfect accuracy, enabling parent-of-origin classification of variants
Williams, C. M.; O'Connell, J.; Freyman, W. A.; 23andMe Research Team, ; Gignoux, C. R.; Ramachandran, S.; Williams, A. L.
10.1101/2024.05.06.592816 — bioinformatics — Posted on 2024-05-10
3438 Epigenenomic and transcriptomic characterization of NPM1-mutated CN-AML subtypes
NGuyen, L.; Tellez Quijorna, C.; Vernerey, J.; Garciaz, S.; Carbuccia, N.; Guille, A.; Burny, C.; Poplineau, M.; Murati, A.; Hospital, M. A.; Vey, N.; Birnbaum, D.; DUPREZ, E.
10.1101/2024.05.07.592738 — genomics — Posted on 2024-05-10
3443 Soybean phenotypic plasticity in response to dark chilling stress
Elmerich, C.; Faucon, M.-P.; Boulch, G.; Jeanson, P.; Lange, B.
10.1101/2024.05.07.592937 — plant biology — Posted on 2024-05-10
3445 A multidisciplinary on-farm survey of maize-bean intercropping highlights key considerations for reviving traditional agricultural systems.
Vazeux-Blumental, N.; Mathieu, L.; Trabac, T.; Palaffre, C.; Lagardere, B.; Carraretto, M.; Bauland, C.; Le Guilloux, M.; Paysant-Le Roux, C.; Caius, J.; Marmagne, A.; Enjalbert, J.; Flutre, T.; Le Cadre, E.; Parnaudeau, V.; Muller, D.; Moenne-Loccoz, Y.; Manicacci, D.; Tenaillon, M. I.
10.1101/2024.04.24.590929 — plant biology — Posted on 2024-05-10
3447 Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation
Daley, J. D.; Mukherjee, E.; Tufino, A. C.; Bailey, N.; Bhaskar, S.; Periyapatna, N.; MacFawn, I.; Kunning, S.; Hinck, C.; Bruno, T.; Olson, A. C.; Mcallister, L. M.; Hinck, A. P.; Cooper, K.; Bao, R.; Cillo, A. R.; Bailey, K. M.
10.1101/2024.05.07.592974 — cancer biology — Posted on 2024-05-10
3451 Dominant negative effects on H3K27 methylation by Weaver syndrome-associated EZH2 variants
Deevy, O.; Monger, C.; Matra, F.; Tuck, E.; Conway, E.; Badonyi, M.; Nimmo, D.; Rodighiero, S.; Zhang, Q.; Davidovich, C.; Marsh, J. A.; Pasini, D.; Bracken, A. P.
10.1101/2023.06.01.543208 — genetics — Posted on 2024-05-10
3456 Plastic responses to past environments shape adaptation to novel selection pressures
Coates, S. E. R.; Comeault, A. A.; Wood, D. P.; Fay, M. F.; Creer, S.; Osborne, O. G.; Dunning, L. T.; Papadopulos, A. S. T.
10.1101/2024.05.06.592784 — evolutionary biology — Posted on 2024-05-10
3458 The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites
Zung, N.; Aravindan, N.; Boshnakovska, A.; Valenti, R.; Preminger, N.; Jonas, F.; Yaakov, G.; Willoughby, M.; Homberg, B.; Keller, J.; Kupervaser, M.; Dezorella, N.; Dadosh, T.; Wolf, S. G.; Itkin, M.; Malitsky, S.; Brandis, A.; Barkai, N.; Fernandez-Busnadiego, R.; Reddi, A.; Rehling, P.; Rapaport, D.; Schuldiner, M.
10.1101/2024.05.09.593285 — cell biology — Posted on 2024-05-10
3459 The Rubicon-WIPI axis regulates exosome biogenesis during aging
Yanagawa, K.; Kuma, A.; Hamasaki, M.; Kita, S.; Yamamuro, T.; Nishino, K.; Nakamura, S.; Omori, H.; Kaminishi, T.; Oikawa, S.; Kato, Y.; Edahiro, R.; Kawagoe, R.; Taniguchi, T.; Tanaka, Y.; Shima, T.; Tabata, K.; Iwatani, M.; Bekku, N.; Hanayama, R.; Okada, Y.; Akimoto, T.; Kosako, H.; Takahashi, A.; Shimomura, I.; Sakata, Y.; Yoshimori, T.
10.1101/2024.05.08.593233 — cell biology — Posted on 2024-05-10
3460 Collagen fibril formation at the plasma membrane occurs independently from collagen secretion
Pickard, A.; Garva, R.; Adamson, A. D.; Calverley, B. C.; Hoyle, A.; Hayward, C.; Spiller, D.; Lu, Y.; Hodson, N. W.; Mandolfo, O.; Kim, K.; Bou-Charios, G.; Swift, J.; Bigger, B.; Kadler, K. E.
10.1101/2024.05.09.593302 — cell biology — Posted on 2024-05-10
3462 Activity-dependent FosB gene expression negatively regulates mast cell functions.
Duque-Wilckens, N.; Maradiaga, N.; Yeh, S.-Y.; Joseph, D.; Srinavasan, V.; Thelen, K.; Sotomayor, F.; Durga, K.; Nestler, E. J.; Moeser, A.; Robison, A. J.
10.1101/2024.05.06.592755 — immunology — Posted on 2024-05-10
3465 Approximated Gene Expression Trajectories (AGETs) for Gene Regulatory Network Inference on Cell Tracks
Spiess, K.; Taylor, S. E.; Fulton, T.; Toh, K.; Saunders, D.; Hwang, S.; Wang, Y.; Paige, B.; Steventon, B.; Verd, B.
10.1101/2022.01.12.476060 — systems biology — Posted on 2024-05-10
3466 Laser NIR irradiation enhances antimicrobial photodynamic inactivation of biofilms of Staphylococcus aureus
Mamone, L.; Tomas, R. S.; Di Venosa, G.; Gandara, L.; Durantini, E.; Buzzola, F.; Casas, A.
10.1101/2024.05.08.593196 — biochemistry — Posted on 2024-05-10
3467 DivIVA controls the dynamics of septum splitting and cell elongation in Streptococcus pneumoniae
Morlot, C.; Trouve, J.; Zapun, A.; Bellard, L.; Juillot, D.; Pelletier, A.; Freton, C.; Baudoin, M.; Carballido-Lopez, R.; Campo, N.; Wong, Y.-S.; Grangeasse, C.
10.1101/2024.05.09.593393 — microbiology — Posted on 2024-05-10
3471 External validation of machine learning models - registered models and adaptive sample splitting
Gallitto, G.; Englert, R.; Kincses, B.; Kotikalapudi, R.; Li, J.; Hoffschlag, K.; Bingel, U.; Spisak, T.
10.1101/2023.12.01.569626 — bioinformatics — Posted on 2024-05-10
3473 LBFextract: unveiling transcription factor dynamics from liquid biopsy data
Lazzeri, I.; Spiegl, B.; Hasenleithner, S. O.; Speicher, M. R.; Kircher, M.
10.1101/2024.05.03.592314 — bioinformatics — Posted on 2024-05-10
3474 Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components
Smith, D. M.; Parekh, P.; Kennedy, J.; Loughnan, R. J.; Frei, O.; Nichols, T. E.; Andreassen, O. A.; Jernigan, T. L.; Dale, A. M.
10.1101/2023.07.17.549390 — neuroscience — Posted on 2024-05-10
3476 Prediction of pathological subthalamic nucleus beta burst occurrence in Parkinson's disease
Abdi-Sargezeh, B.; Shirani, S.; Sharma, A.; Green, A.; Akram, H.; Zrinzo, L.; Limousin, P.; Foltynie, T.; Denison, T.; Tan, H.; Litvak, V.; Oswal, A.
10.1101/2024.05.09.593398 — neuroscience — Posted on 2024-05-10
3477 Modification of xylan in secondary walls alters cell wall biosynthesis and wood formation programs
Sivan, P.; Urbancsok, J.; Donev, E. N.; Derba-Maceluch, M.; Barbut, F. R.; Yassin, Z.; Gandla, M. L.; Mitra, M.; Heinonen, S. E.; Simura, J.; Cermanova, K.; Karady, M.; Scheepers, G.; Jönsson, L. J.; Master, E. R.; Vilaplana, F.; Mellerowicz, E. J.
10.1101/2024.05.02.592170 — plant biology — Posted on 2024-05-10
3478 Suppressing APOE4-induced mortality and cellular damage by targeting VHL
Jiang, W.; Cao, Y.; Xue, Y.; Ji, Y.; Winer, B. Y.; Zhang, M.; Singhal, N. S.; Pierce, J.; Chen, S.; Ma, D. K.
10.1101/2024.02.28.582664 — physiology — Posted on 2024-05-10
3479 Deep generative modeling of sample-level heterogeneity in single-cell genomics
Boyeau, P.; Hong, J.; Gayoso, A.; Kim, M.; McFaline-Figueroa, J. L.; Jordan, M.; Azizi, E.; Ergen, C.; Yosef, N.
10.1101/2022.10.04.510898 — bioinformatics — Posted on 2024-05-10
3487 Prefrontal 5α-reductase 2 mediates male-specific acute stress response
Cadeddu, R.; Braccagni, G.; Floris, G.; Branca, C.; Corridori, E.; Salviati, S.; Sanchez, P.; Santovito, L. S.; Torres, J. M.; Ortega, E.; Pinna, G.; Moos, P. J.; Scheggi, S.; Bortolato, M.
10.1101/2024.05.07.593076 — neuroscience — Posted on 2024-05-10
3489 Morphotype-specific calcium signaling in human microglia
Nevelchuk, S.; Brawek, B.; Schwarz, N.; Valiente-Gabioud, A.; Wuttke, T. V.; Kovalchuk, Y.; Koch, H.; Hoellig, A.; Steiner, F.; Figarella, K.; Griesbeck, O. V.; Garaschuk, O.
10.1101/2024.05.06.592754 — immunology — Posted on 2024-05-10
3490 Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues
Narasimhan, H.; Richter, M. L.; Shakiba, R.; Papaioannou, N. E.; Stehle, C.; Ravi Rengarajan, K.; Ulmert, I.; Küntzel, V.; Stange, E.-L.; Antonova, A. U.; Klein, L.; Dudziak, D.; Colonna, M.; Torow, N.; Hornef, M. W.; Lahl, K.; Romagnani, C.; Colome-Tatche, M.; Schraml, B. U.
10.1101/2024.05.06.592772 — immunology — Posted on 2024-05-10
3491 Exonic splice variant discovery using in vitro models of inherited retinal disease
Mullin, N. K.; Bohrer, L. R.; Anfinson, K. R.; Andorf, J. L.; Mullins, R. F.; Tucker, B. A.; Stone, E. M.
10.1101/2024.05.06.592740 — genetics — Posted on 2024-05-10
3493 Microglia regulate motor neuron plasticity via reciprocal fractalkine/adenosine signaling
Marciante, A. B.; Tadjalli, A.; Burrowes, K. A.; Oberto, J. R.; Luca, E. K.; Seven, Y. B.; Nikodemova, M.; Watters, J. J.; Baker, T. L.; Mitchell, G. S.
10.1101/2024.05.07.592939 — physiology — Posted on 2024-05-09
3494 AAV-mediated genome editing is influenced by the formation of R-loops
Puzzo, F.; Crossley, M. P.; Goswami, A.; Zhang, F.; Pekrun, K.; Garzon, J.; Cimprich, K.; Kay, M. A.
10.1101/2024.05.07.592855 — molecular biology — Posted on 2024-05-09
3495 Genetically edited placental organoids cast new light on the role of ACE2 in placental development
Arthurs, A. L.; Dietrich, B.; Knoefler, M.; Lushington, C. J.; Thomas, P. Q.; Adikusuma, F.; Jankovic-Karasoulos, T.; Smith, M. D.; Pringle, K. G.; Roberts, C. T.
10.1101/2024.05.09.592870 — molecular biology — Posted on 2024-05-09
3496 Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1
Kozlov, G.; Jiang, J.; Rutherford, T.; Noronha, A.; Wilds, C.; Gehring, K.
10.1101/2024.05.08.593157 — biochemistry — Posted on 2024-05-09
3499 Native β-barrel substrates pass through two shared intermediates during folding on the BAM complex
Santos, T. M. A.; Thomson, B. D.; Marquez, M. D.; Pan, L.; Monfared, T. H.; Kahne, D. E.
10.1101/2024.05.09.593409 — biochemistry — Posted on 2024-05-09
3501 Structural basis for catalysis and selectivity of phospholipid synthesis by eukaryotic choline-phosphotransferase
Roberts, J. R.; Horibata, Y.; Kwarcinski, F. E.; Lam, V.; Raczkowski, A. M.; Hubbard, A.; Sugimoto, H.; White, B.; Tall, G. G.; Ohi, M. D.; Maeda, S.
10.1101/2024.05.09.593427 — biochemistry — Posted on 2024-05-09
3502 Assembly of a segrosome by a CTP-independent ParB-like protein
Sukhoverkov, K. V.; Balaguer-Perez, F.; Aicart-Ramos, C.; Maqbool, A.; Chandra, G.; Moreno-Herrero, F.; Le, T. B. K.
10.1101/2024.05.08.592561 — microbiology — Posted on 2024-05-09
3506 Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide
Rush, J. S.; Zamakhaeva, S.; Murner, N. R.; Deng, P.; Morris, A. J.; Kenner, C. W.; Black, I.; Heiss, C.; Azadi, P.; Korotkov, K. V.; Widmalm, G.; Korotkova, N.
10.1101/2024.05.09.593426 — microbiology — Posted on 2024-05-09
3507 Fluid flow overcomes antimicrobial resistance by boosting delivery
Shuppara, A. M.; Padron, G. C.; Sharma, A.; Modi, Z.; Koch, M. D.; Sanfilippo, J. E.
10.1101/2024.05.08.591722 — microbiology — Posted on 2024-05-09
3508 Neurocomputational Mechanisms Underlying Maladaptive Self-Belief Formation in Depression
Czekalla, N.; Schröder, A.; Mayer, A. V.; Stierand, J.; Stolz, D. S.; Kube, T.; Wilhelm-Groch, I.; Klein, J. P.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.
10.1101/2024.05.09.593087 — neuroscience — Posted on 2024-05-09
3511 Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibility
Cording, K. R.; Tu, E. M.; Wang, H.; Agopyan-Miu, A. H. C. W.; Bateup, H. S.
10.1101/2024.05.09.593387 — neuroscience — Posted on 2024-05-09
3512 varVAMP: automated pan-specific primer design for tiled full genome sequencing and qPCR of highly diverse viral pathogens.
Fuchs, J.; Kleine, J.; Schemmerer, M.; Kreibich, J.; Maier, W.; Battur, N.; Krannich, T.; Sedaghatjoo, S.; Jaki, L.; Maks, A.; Boehm, C.; Wilhelm, C.; Schulze, J.; Mache, C.; Berger, E.; Panajotov, J.; Eidenschink, L.; Gruening, B.; Bauswein, M.; Boettcher, S.; Johne, R.; Wenzel, J.; Hoelzer, M.; Panning, M.
10.1101/2024.05.08.593102 — bioinformatics — Posted on 2024-05-09
3513 Structure of the human CTF18 clamp loader bound to PCNA
Briola, G.; Tehseen, M.; Al-Amodi, A.; Nguyen, P. Q.; Savva, C. G.; Hamdan, S. M.; De Biasio, A.
10.1101/2024.05.08.593111 — biochemistry — Posted on 2024-05-09
3515 Controllable multi-halogenation of a non-native substrate by SyrB2 iron halogenase
Wilson, R. H.; Chatterjee, S.; Smithwick, E. R.; Rama Damodaran, A.; Bhagi-Damodaran, A.
10.1101/2024.05.08.593161 — biochemistry — Posted on 2024-05-09
3519 Genomic exploration of the complex journey of Plasmodium vivax in Latin America
Lefebvre, M. J. M.; Degrugillier, F.; Arnathau, C.; Fontecha, G. A.; Noya, O.; Houze, S.; Severini, C.; Pradines, B.; Berry, A.; Trape, J.-F.; Saenz, F. E.; Prugnolle, F.; Fontaine, M. C.; Rougeron, V.
10.1101/2024.05.08.592893 — genomics — Posted on 2024-05-09
3520 Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation
han, p.; Chen, S.; Yin, J.; Liang, J.; Zhang, W.; Jiang, P.; Wang, W.; Chen, X.; Zhou, Y.; Xia, P.; Yang, F.; Gu, Y.; Zhang, R.
10.1101/2024.05.09.593293 — developmental biology — Posted on 2024-05-09
3527 H2 consumption by acetogenic bacteria follows first-order kinetics
Munoz, L.; Chakraborty, S.; Gron, L. V.; Bambace, M. F.; Catalano, J.; Philips, J.
10.1101/2024.05.08.593002 — microbiology — Posted on 2024-05-09
3528 Basic reproduction number for pandemic Escherichia coli clones is comparable to typical pandemic viruses
Ojala, F. A.; Pesonen, H.; Gladstone, R. A.; Maklin, T.; Tonkin-Hill, G.; Marttinen, P.; Corander, J.
10.1101/2024.05.08.593267 — microbiology — Posted on 2024-05-09
3529 Endogenous retrovirus ERV-DC8 highly integrated in domestic cat populations is a replication-competent provirus
Pramono, D.; Muto, Y.; Shimazu, Y.; Deshapriya, R. M. C.; Makundi, I.; Arnal, M.; de Luco, D. F.; Ha Ngo, M.; Miyake, A.; Nishigaki, K.
10.1101/2024.05.09.593269 — microbiology — Posted on 2024-05-09
3530 Broadening sarbecovirus neutralization with bispecific antibodies combining distinct conserved targets on the receptor binding domain
Guerra, D.; Radic, L.; Brinkkemper, M.; Poniman, M.; van der Maas, L.; Torres, J. L.; Ward, A. B.; Sliepen, K.; Schinkel, J.; Sanders, R. W.; van Gils, M. J.; Beaumont, T.
10.1101/2024.05.09.593284 — microbiology — Posted on 2024-05-09
3531 Eubacterium rectale detoxification mechanism increases resilience of the gut environment
Richie, T. G.; Wiechman, H.; Ingold, C.; Heeren, L.; Kamke, A.; Pogranichniy, S.; Monk, K.; Summers, T.; Ran, Q.; Sarkar, S.; Plattner, B. L.; Sidebottom, A. M.; Chang, E.; Lee, S. T. M.
10.1101/2024.05.09.593360 — microbiology — Posted on 2024-05-09
3533 Revealing the taxonomy and functional potential of urban soil microbiomes
Stohel, I. L.; Song, Y.; Turetcaia, A.; Wilson, A. J.; Schmidt, D. E.; Yarwood, S. A.; Townsend, A.; Graham, E. B.
10.1101/2024.05.09.592449 — microbiology — Posted on 2024-05-09
3534 Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors
Patel, D. T.; Stogios, P. J.; Jaroszewski, L.; Ubanus, M.; Sedova, M.; Semper, C.; Le, C.; Takkouche, A.; Ichii, K.; Innabi, J.; Patel, D. H.; Ensminger, A. W.; Godzik, A.; Savchenko, A.
10.1101/2024.05.09.593423 — microbiology — Posted on 2024-05-09
3537 A Mutation in Tmem135 Causes Progressive Sensorineural Hearing Loss
Kim, M.-J.; Simms, S. S.; Behnammanesh, G.; Honkura, Y.; Suzuki, J.; Park, H.-J.; Milani, M.; Katori, Y.; Bird, J. E.; Ikeda, A.; Someya, S.
10.1101/2024.05.09.593414 — neuroscience — Posted on 2024-05-09
3540 Hypergraph Cortical Cytoarchitectonic Parcellation with Multimodal Canine Brain Atlas
Zhai, S.; Jiang, C.; Chen, Z.; Yu, D.; Gul, I.; Yuan, X.; Song, H.; Liu, Y.; Zhang, Z.; Xu, T.; Xu, H.; Wan, J.; Mao, A.; Li, J.; Han, Y.; Qin, P.
10.1101/2024.05.09.593154 — neuroscience — Posted on 2024-05-09
3541 Cell type- and layer-specific plasticity of olfactory bulb interneurons following olfactory sensory neuron ablation
Kunkhyen, T.; Brechbill, T. R.; Berg, S. P.; Pothuri, P.; Rangel, A. N.; Gupta, A.; Cheetham, C. E. J.
10.1101/2024.05.08.593238 — neuroscience — Posted on 2024-05-09
3542 Reward perseveration is shaped by GABAA-mediated dopamine pauses
Burwell, S. C. V.; Yan, H.; Lim, S. S. X.; Shields, B. C.; TADROSS, M. R.
10.1101/2024.05.09.593320 — neuroscience — Posted on 2024-05-09
3544 Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils
Etani, H.; Takatori, S.; Wang, W.; Omi, J.; Akahori, A.; Watanabe, H.; Sonn, I.; Okano, H.; Hara, N.; Hasegawa, M.; Miyashita, A.; Kikuchi, M.; Ikeuchi, T.; Morishima, M.; Saito, Y.; Murayama, S.; Saito, T.; Saido, T. C.; Takai, T.; Ohwada, T.; Aoki, J.; Tomita, T.
10.1101/2024.05.08.593262 — neuroscience — Posted on 2024-05-09
3545 Limited cognitive resources reduce the language predictability benefit across the adult lifespan
Schuckart, M. M.; Martin, S.; Tune, S.; Schmitt, L.-M.; Hartwigsen, G.; Obleser, J.
10.1101/2024.05.08.592872 — neuroscience — Posted on 2024-05-09
3546 A TRANSLAMINAR SPACETIME CODE SUPPORTS TOUCH-EVOKED TRAVELING WAVES
Gonzales, D. L.; Khan, H. F.; Keri, H. V. S.; Yadav, S.; Steward, C.; Muller, L.; Pluta, S.; Jayant, K.
10.1101/2024.05.09.593381 — neuroscience — Posted on 2024-05-09
3547 Fitness incentives to male fighters undermine fighting performance in intergroup contests
Green, P. A.; Sankey, D. W. E.; Collins, T.; Mwanguhya, F.; Nichols, H. J.; Cant, M.; Thompson, F. J.
10.1101/2024.05.09.593361 — animal behavior and cognition — Posted on 2024-05-09
3550 Intestinal epigenomic alterations are associated with a dysregulated nutrient absorption phenotype in obesity
Badurdeen, D. S.; Li, Z.; Lee, J.-H.; Ma, T.; Bhagwate, A. V.; Latanich, R.; Dogiparthi, A.; Ordog, T.; Kovbasnjuk, O.; Kumbhari, V.; Foulke-Abel, J.
10.1101/2024.05.06.591758 — genomics — Posted on 2024-05-09
3553 Engineering an fgfr4 knockout zebrafish to study its role in development and disease
Harrison, E. N.; Jay, A. N.; Kent, M. R.; Sukienik, T. P.; LaVigne, C. A.; Kendall, G. C.
10.1101/2024.05.08.593184 — developmental biology — Posted on 2024-05-09
3556 A conserved chronobiological complex times C. elegans development
Spangler, R. K.; Ashley, G. E.; Braun, K.; Wruck, D.; Ramos-Coronado, A.; Ragle, J. M.; Iesmantavicius, V.; Hess, D.; Partch, C. L.; Grosshans, H.; Ward, J. D.
10.1101/2024.05.09.593322 — developmental biology — Posted on 2024-05-09
3557 Anatomics MLT, an AI tool for large scale quantification of ultrastructural traits
Brookhouse, A.; Ji, Y.; Knoblauch, J.; Gaburak, P.; Wager, B. M.; Lin, Z.; Kunz, H.-H.; Gebremedhin, A. M.; Pfister, H.; Peters, W. S.; Wei, D.; Knoblauch, M.
10.1101/2024.05.06.592763 — cell biology — Posted on 2024-05-09
3558 Dataset factors influencing age-related changes in brain structure and function in neurodevelopmental conditions
Vandewouw, M. M.; Ye, Y. J.; Crosbie, J.; Schachar, R. J.; Iaboni, A.; Georgiades, S.; Nicolson, R.; Kelley, E.; Ayub, M.; Jones, J.; Arnold, P. D.; Taylor, M. J.; Lerch, J. P.; Anagnostou, E.; Kushki, A.
10.1101/2024.05.09.591294 — neuroscience — Posted on 2024-05-09
3559 Discovery and characterization of stereodefined PMO-gapmers targeting tau
Kanatsu, K.; Takahashi, Y.; Sakaguchi, T.; Kim, D.-S.; Murota, M.; Shan, M.; Fukami, K.; Itano, W.; Kikuta, K.; Yoshimura, H.; Kurokawa, T.; Nagayama, Y.; Ishikawa, R.; Dairiki, R.; Zhou, Z.; Sanders, K.; Stupalski, J.; Yasui, S.; Liu, D.; Benayoud, F.; Fang, H.; Jing, E.; Ogo, M.; Fang, F. G.; Wang, J.; Choi, H.-w.
10.1101/2024.05.09.591947 — neuroscience — Posted on 2024-05-09
3561 USP14 regulates pS129 α-synuclein levels and oxidative stress in human SH-SY5Y dopaminergic cells
Srinivasan, V.; Soliymani, R.; Ivanova, L.; Eriksson, O.; Peitsaro, N.; Lalowski, M.; Karelson, M.; Lindholm, D.
10.1101/2024.05.09.592905 — neuroscience — Posted on 2024-05-09
3562 Mechanical Properties of White Matter Tracts in Aging Assessed via Anisotropic MR Elastography
Caban-Rivera, D. A.; Williams, L. T.; McGarry, M. D. J.; Smith, D. R.; Van Houten, E. E. W.; Paulsen, K. D.; Bayly, P. V.; Johnson, C. L.
10.1101/2024.05.08.593260 — neuroscience — Posted on 2024-05-09
3564 Intracranial neurophysiological correlates of rumination
Chen, X.; Fan, Z.; Chen, D.; Wang, L.; Chen, L.; Yan, C.-G.
10.1101/2024.05.08.593187 — neuroscience — Posted on 2024-05-09
3566 Ability to monitor deviations of own movement without visual feedback
Brandt, I. M.; Bjerregaard, S. M.; Jensen, D. B.; Giessing, M. G.; Grunbaum, T.; Christensen, M. S.
10.1101/2024.05.09.593337 — neuroscience — Posted on 2024-05-09
3567 Prediction of pathological subthalamic nucleus beta burst occurrence in Parkinson's disease
Abdi-Sargezeh, B.; Shirani, S.; Sharma, A.; Green, A.; Akram, H.; Zrinzo, L.; Limousin, P.; Foltynie, T.; Denison, T.; Tan, H.; Litvak, V.; Oswal, A.
10.1101/2024.05.09.593398 — neuroscience — Posted on 2024-05-09
3568 Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
Sokratian, A.; Zhou, Y.; Tatli, M.; Burbidge, K. J.; Xu, E.; Viverette, E.; Duda, A. M.; Yuan, Y.; Li, H.; Strader, S.; Patel, N.; Shiell, L.; Malankhanova, T.; Chen, O.; Mazzulli, J. R.; Perera, L.; Stahlberg, H.; Borgnia, M. J.; Bartesaghi, A.; Lashuel, H.; West, A.
10.1101/2024.05.09.593334 — neuroscience — Posted on 2024-05-09
3571 Extensive MEG time-series phenotyping unveils neural markers predictive of age
Stier, C.; Balestrieri, E.; Fehring, J.; Focke, N. K.; Wollbrink, A.; Dannlowski, U.; Gross, J.
10.1101/2024.05.09.593348 — neuroscience — Posted on 2024-05-09
3574 Delineating neural contributions to electroencephalogram-based speech decoding
Sato, M.; Kabe, Y.; Nobe, S.; Yoshida, A.; Inoue, M.; Shimizu, M.; Tomeoka, K.; Sasai, S.
10.1101/2024.05.09.591996 — neuroscience — Posted on 2024-05-09
3575 Gelatinous fibers develop asymmetrically for posture support of bends and coils in common bean vine
Onyenedum, J. G.; Sousa-Baena, M. S.; Acevedo, A. A.; Hunt, L.; Glos, R. A. E.; Anderson, C. T.
10.1101/2024.05.06.592750 — plant biology — Posted on 2024-05-09
3576 Post-translational Modification of α-Synuclein Modifies Monomer Dynamics and Aggregation Kinetics
Gamage, K.; Wang, B.; Hard, E.; Van, T.; Galesic, A.; Phillips, G.; Pratt, M. R.; Lapidus, L.
10.1101/2024.05.06.592473 — biophysics — Posted on 2024-05-09
3578 Predictive Immunoinformatics Reveal Promising Safety and Anti-Onchocerciasis Protective Immune Response Profiles to Vaccine Candidates (Ov-RAL-2 and Ov-103) in Anticipation of Phase I Clinical Trials
Nebangwa, D. N.; Shey, R. A.; Shadrack, D. M.; Shintouo, C. M.; Yaah, N. E.; Yengo, B. N.; Gwei, K. Y.; Fomekong, D. B. A.; Nchanji, G. T.; Efeti, M. T.; Lemoge, A. A.; Ntie-Kang, F.; Ghogomu, S. M.
10.1101/2024.05.06.592733 — bioinformatics — Posted on 2024-05-09
3579 Digital Profiling of Tumor Extracellular Vesicle-associated RNAs Directly from Unprocessed Blood Plasma
Clarissa, E. M.; Kumar, S.; Park, J.; Karmacharya, M.; Oh, I.-J.; Kim, M.-H.; Ryu, J.-S.; Cho, Y.-K.
10.1101/2024.05.06.592543 — bioengineering — Posted on 2024-05-09
3582 Boosting the toolbox for live imaging of translation
Bellec, M.; Chen, R.; Dhayni, J.; Trullo, A.; Avinens, D.; Karaki, H.; Mazzarda, F.; Lenden-Hasse, H.; Favard, C.; Lehmann, R.; Bertrand, E.; Lagha, M.; Dufourt, J.
10.1101/2023.02.25.529998 — developmental biology — Posted on 2024-05-09
3583 Automated Cytometric Gating with Human-Level Performance Using Bivariate Segmentation
Chen, J.; Ionita, M.; Feng, Y.; Lu, Y.; Orzechowski, P.; Garai, S.; Hassinger, K.; Bao, J.; Wen, J.; Duong-Tran, D.; Wagenaar, J.; McKeague, M. L.; Painter, M. M.; Mathew, D.; Pattekar, A.; Meyer, N. J.; Wherry, E. J.; Greenplate, A. R.; Shen, L.
10.1101/2024.05.06.592739 — immunology — Posted on 2024-05-09
3584 Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.
Chartampila, E.; Leary, P.; Elayouby, K. S.; LaFrancois, J. J.; Alcantara-Gonzalez, D.; Jain, S.; Gerencer, K.; Botterill, J. J.; Ginsberg, S. D.; Scharfman, H.
10.1101/2023.05.12.540428 — neuroscience — Posted on 2024-05-09
3587 E.PathDash, pathway activation analysis of publicly available pathogen gene expression data
Taub, L.; Hampton, T. H.; Sarkar, S.; Doing, G.; Neff, S. L.; Finger, C. E.; Fukutani, K. F.; Stanton, B. A.
10.1101/2024.04.10.588749 — bioinformatics — Posted on 2024-05-09
3589 Phylogeography of bar-tailed godwits: pre-LGM structure in Beringia and westward colonization of post-glacial Europe
Conklin, J. R.; Verkuil, Y. I.; Lefebvre, M. J. M.; Battley, P. F.; Bom, R. A.; Gill, R. E.; Hassell, C. J.; ten Horn, J.; Ruthrauff, D. R.; Tibbitts, T. L.; Tomkovich, P. S.; Warnock, N.; Piersma, T.; Fontaine, M. C.
10.1101/2024.04.22.590527 — evolutionary biology — Posted on 2024-05-09
3594 Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
Syed, F.; Ballew, O.; Lee, C.-C.; Rana, J.; Krishnan, P.; Castela, A.; Weaver, S. A.; Chalasani, N. S.; Thomaidou, S. F.; Demine, S.; Chang, G.; Coomans de Brachene, A.; Alvelos, M. I.; Marselli, L.; Orr, K.; Felton, J. L.; Liu, J.; Marchetti, P.; Zaldumbide, A.; Scheuner, D.; Eizirik, D. L.; Evans-Molina, C.
10.1101/2024.03.20.585925 — physiology — Posted on 2024-05-09
3595 Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking
Sokol, K. H.; Lee, C. J.; Rogers, T. J.; Waldhart, A.; Ellis, A. E.; Madireddy, S.; Daniels, S. R.; Ye, X.; Olesnavich, M.; Johnson, A.; Furness, B. R.; Sheldon, R. D.; Lien, E. C.
10.1101/2024.05.06.592780 — cancer biology — Posted on 2024-05-09
3601 Tadpoles rely on mechanosensory stimuli for communication when visual capabilities are poor
Butler, J. M.; McKinney, J.; Ludington, S. C.; Mabogunje, M.; Baker, P.; Singh, D.; Edwards, S. V.; O'Connell, L. A.
10.1101/2022.10.18.512729 — developmental biology — Posted on 2024-05-09
3605 Comparative metagenomic profiling of seed-borne microbiomes in a landrace and a hybrid maize variety
Henaut-Jacobs, S.; Cyriaco, B. E. B.; Pedrosa-Silva, F.; Olivares, F. L.; Venancio, T. M.
10.1101/2024.04.04.588073 — plant biology — Posted on 2024-05-09
3607 Targeting SCD triggers lipotoxicity of cancer cells and enhances anti-tumor immunity in breast cancer brain metastasis mouse models
Sammarco, A.; Guerra, G.; Eyme, K. M.; Kennewick, K.; Qiao, Y.; El Hokayem, J.; Williams, K. J.; Su, B.; Zappulli, V.; Bensinger, S. J.; Badr, C. E.
10.1101/2024.05.06.592766 — cancer biology — Posted on 2024-05-09
3608 Physical confinement selectively favours bacterial growth based on cell shape
Sreepadmanabh, M.; Ganesh, M.; Sanjenbam, P.; Kurzthaler, C.; Agashe, D.; Bhattacharjee, T.
10.1101/2024.05.06.592621 — biophysics — Posted on 2024-05-09
3609 Polymer-tethered quenched fluorescent probes for enhanced imaging of tumor associated proteases
Hadzima, M.; Faucher, F. F.; Blazkova, K.; Yim, J. J.; Guerra, M.; Chen, S.; Woods, E. C.; Park, K. W.; Sacha, P.; Subrt, V.; Kostka, L.; Etrych, T.; Konvalinka, J.; Bogyo, M.
10.1101/2024.05.06.592849 — bioengineering — Posted on 2024-05-09
3613 Using a decision tree to predict COVID case numbers: a tutorial for beginners
Moctezuma Tan, L.; Benitez, L.; van Nouhuijs, F.; Orcales, F.; Kim, A.; Campbell, R.; Fuse, M.; Pennings, P. S.
10.1101/2023.12.19.572463 — scientific communication and education — Posted on 2024-05-09
3614 Inactivation of mitochondrial complex IV in Physcomitrium patens reveals the essential role of respiration in coordinating plants metabolism
Vera-Vives, A. M.; Mellon, M.; Libero, G.; Westhoff, P.; Segalla, A.; Bizzotto, E.; Campanaro, S.; Sparla, F.; Weber, A. P. M.; Alboresi, A.; Morosinotto, T.
10.1101/2024.05.06.592826 — plant biology — Posted on 2024-05-09
3615 Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions
Solosky, A. M.; Claudio, I. M.; Chappel, J. R.; Kirkwood-Donelson, K. I.; Janech, M. G.; Bland, A. M.; Gulland, F.; Neely, B. A.; Baker, E.
10.1101/2024.05.06.592757 — bioinformatics — Posted on 2024-05-09
3616 Serum mitochondrial bioenergetics as fingerprint of the hepatic one: how to monitor genetic MASLD
Paolini, E.; Longo, M.; Meroni, M.; Podini, P.; Maggioni, M.; Quattrini, A.; Fracanzani, A. L.; Dongiovanni, P.
10.1101/2024.05.06.592717 — genetics — Posted on 2024-05-09
3622 The paradox of extremely fast evolution driven in multi-copy gene systems - A resolution
Wang, X.; Ruan, Y.; Zhang, L.; Chen, X.; Shi, Z.; Chen, B.; Tracy, M.; Wen, H.; Wu, C.-I.
10.1101/2023.06.14.545040 — evolutionary biology — Posted on 2024-05-09
3623 Longitudinal transcriptional changes reveal genes from the natural killer cell-mediated cytotoxicity pathway as critical players underlying COVID-19 progression
Medina, M. A.; Fuentes-Villalobos, F.; Quevedo, C.; Aguilera, F.; Riquelme, R.; Rioseco, M. L.; Barria, S.; Pinos, Y.; Calvo, M.; Burbulis, I.; Kossack, C.; Alvarez, R. A.; Garrido, J. L.; Barria, M. I.
10.1101/2024.01.02.573936 — immunology — Posted on 2024-05-09
3626 Placental and Immune Cell DNA Methylation Reference Panel for Bulk Tissue Cell Composition
Campbell, K. A.; Colacino, J. A.; Dou, J.; Dolinoy, D. C.; Park, S. K.; Loch-Caruso, R.; Padmanabhan, V.; Bakulski, K.
10.1101/2024.05.06.588886 — genomics — Posted on 2024-05-09
3631 Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in situ
Li, Y.; Arghittu, S. M.; Dietz, M. S.; Hella, G. J.; Hasse, D.; Ferraris, D. M.; Freund, P.; Barth, H.-D.; Niemann, H. H.; Covino, R.; Heilemann, M.
10.1101/2023.12.22.572978 — biophysics — Posted on 2024-05-09
3632 Energy partitioning in the cell cortex
Chen, S.; Seara, D.; Michaud, A.; Kim, S.; Bement, W.; Murrell, M.
10.1101/2024.05.06.592707 — biophysics — Posted on 2024-05-09
3635 Pooled screening for CAR function identifies novel IL13Rα2-targeted CARs for treatment of glioblastoma
Gordon, K. S.; Perez, C.; Garmilla, A.; Lam, M. S.; Aw, J. J.; Datta, A.; Lauffenburger, D. A.; Pavesi, A.; Birnbaum, M. E.
10.1101/2024.04.04.586240 — immunology — Posted on 2024-05-09
3638 Are human connectomes heritable?
Chung, J.; Bridgeford, E. W.; Powell, M.; Pisner, D.; Xu, T.; Vogelstein, J. T.
10.1101/2023.04.02.532875 — neuroscience — Posted on 2024-05-09
3639 Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
Held, M.; Bisen, R. S.; Zandawala, M. M.; Chockley, A. S.; Balles, I. S.; Hilpert, S.; Liessem, S.; Cascino-Milani, F.; Ache, J. M.
10.1101/2023.09.14.557555 — neuroscience — Posted on 2024-05-09
3643 Coordinated molecular and ecological adaptations underlie a highly successful parasitoid
Pang, L.; Fang, G.; Liu, Z.; Dong, Z.; Chen, J.; Feng, T.; Zhang, Q.; Sheng, Y.; Lu, Y.; Wang, Y.; Zhang, Y.; Li, G.; Chen, X.; Zhan, S.; Huang, J.
10.1101/2024.01.08.574671 — ecology — Posted on 2024-05-09
3644 Nuclear membrane protein Bqt4 maintains nuclear envelope integrity by recruiting phosphatidic acid
Hirano, Y.; Sato, T.; Miura, A.; Kubota, Y.; Shindo, T.; Fukase, K.; Fukagawa, T.; Kabayama, K.; Haraguchi, T.; Hiraoka, Y.
10.1101/2023.12.21.572941 — cell biology — Posted on 2024-05-09
3645 Clearance of protein aggregates during cell division
Du, S.; Wang, Y.; Chen, B.; Xie, S.; Chan, K. Y.; Hay, D. C.; Chew, T. G.
10.1101/2024.02.10.579754 — cell biology — Posted on 2024-05-09
3654 The impact of host heterogeneity on pathogen evolution depends on spatial structure
Visher, E.; Ali, A.; Barajas, J.; Masud, S.; McBride, A.; Ramos, E.; Sui, M.; Villalobos-Heredia, C.; Walzer, N.; White, P. S.; Boots, M.
10.1101/2023.05.12.540593 — evolutionary biology — Posted on 2024-05-09
3656 A natural disaster exacerbates and redistributes disease risk across free-ranging macaques by altering social structure
Motes-Rodrigo, A.; Albery, G. F.; Negron-Del Valle, J.; Philips, D.; Cayo Biobank Research Unit, ; Platt, M.; Brent, L. J.; Testard, C.
10.1101/2023.07.17.549341 — ecology — Posted on 2024-05-09
3657 IDENTIFICATION OF AN EARLY SUBSET OF CEREBELLAR NUCLEI NEURONS IN MICE
Rahimi-Balaei, M.; Amiri, S.; Lamonerie, T.; Wu, S.-R.; Zoghbi, H. Y.; Consalez, G. G.; Goldowitz, D.; Marzban, H.
10.1101/212571 — developmental biology — Posted on 2024-05-09
3658 Large-scale statistical mapping of T-cell receptor β sequences to Human Leukocyte Antigens
Zahid, H. J.; Taniguchi, R.; Ebert, P.; Chow, I.-T.; Gooley, C.; Lv, J.; Pisani, L.; Rusnak, M.; Elyanow, R.; Takamatsu, H.; Zhou, W.; Greissl, J.; Robins, H.; Carlson, J. M.
10.1101/2024.04.01.587617 — immunology — Posted on 2024-05-09
3659 Pattern completion and disruption characterize contextual modulation in the visual cortex
Fu, J.; Shrinivasan, S.; Baroni, L.; Ding, Z.; Fahey, P. G.; Pierzchlewicz, P.; Ponder, K.; Froebe, R.; Ntanavara, L.; Muhammad, T.; Willeke, K. F.; Wang, E.; Ding, Z.; Tran, D. T.; Papadopoulos, S.; Patel, S.; Reimer, J.; Ecker, A. S.; Pitkow, X.; Antolik, J.; Sinz, F. H.; Haefner, R. M.; Tolias, A. S.; Franke, K.
10.1101/2023.03.13.532473 — neuroscience — Posted on 2024-05-09
3661 Sex-specific mechanisms of cerebral microvascular BKCa dysfunction in a mouse model of Alzheimer's disease
da Silva, J. F.; Polk, F. D.; Martin, P. E.; Thai, S. H.; Savu, A.; Gonzales, M.; Kath, A. M.; Gee, M. T.; Pires, P. W.
10.1101/2023.06.06.543962 — physiology — Posted on 2024-05-09
3662 Methods for evaluating unsupervised vector representations of genomic regions
Zheng, G.; Rymuza, J.; Gharavi, E.; LeRoy, N. J.; Zhang, A.; Sheffield, N. C.
10.1101/2023.08.28.555137 — bioinformatics — Posted on 2024-05-09
3663 Quantification of histone H1 subtypes using targeted proteomics.
Lopez-Gomez, J.; Villareal, L.; Andres, M.; Ponte, I.; Xicoy, B.; Zamora, L.; Vilaseca, M.; Roque, A.
10.1101/2024.01.20.576464 — biochemistry — Posted on 2024-05-09
3667 Filament formation activates protease and ring nuclease activities of CRISPR SAVED-Lon
Smalakyte, D.; Ruksenaite, A.; Sasnauskas, G.; Tamulaitiene, G.; Tamulaitis, G.
10.1101/2024.05.08.593097 — biochemistry — Posted on 2024-05-08
3668 Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Non-structural Proteins Inhibitors
Lu, X.; Hu, H.; Mei, L.; Wang, X.; Xiong, L.; Zhu, Y.; Liu, S.; Zhao, W.; Mengnisa, S.; Li, L.; Lin, X.; Liu, J.; Wang, X.; Duan, Z.; Lu, W.; Suo, Y.; Wu, X.; Cui, M.; Yue, J.; Xu, Y.
10.1101/2024.05.08.593105 — biochemistry — Posted on 2024-05-08
3669 Domain consolidation in Bacterial 50S assembly revealed by Anti-Sense Oligonucleotide Probing
Sheng, K.; Dong, X.; Aiyer, S.; Lee, J.; Marquardt, S. D.; Lyumkis, D.; Williamson, J. R.
10.1101/2024.05.08.593220 — biochemistry — Posted on 2024-05-08
3670 The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease
Binder, S. C.; Schneberger, N.; Engeser, M.; Geyer, M.; Rouillon, C.; Hagelueken, G.
10.1101/2024.05.08.593092 — biochemistry — Posted on 2024-05-08
3671 De novo gene synthesis by an antiviral reverse transcriptase
Tang, S.; Conte, V.; Zhang, D. J.; Zedaveinyte, R.; Lampe, G. D.; Wiegand, T.; Tang, L. C.; Wang, M.; Walker, M. W. G.; George, J. T.; Berchowitz, L. E.; Jovanovic, M.; Sternberg, S. H.
10.1101/2024.05.08.593200 — molecular biology — Posted on 2024-05-08
3675 Novel introductions of human-origin H3N2 Influenza viruses in Swine, Chile
Aguero, B.; Ariyama, N.; Berrios, F.; Quezada, B.; Enciso, N.; Medina, R.; Neira, V.
10.1101/2024.05.08.593172 — microbiology — Posted on 2024-05-08
3676 Succession of bacteria and archaea within the soil micro-food web
Tamang, M.; Sikorski, J.; van Bommel, M.; Piecha, M.; Urich, T.; Ruess, L.; Huber, K. J.; Neumann-Schaal, M.; Pester, M.
10.1101/2024.05.08.593117 — microbiology — Posted on 2024-05-08
3678 The microbiome shapes immunity in a sex-specific manner in mouse models of Alzheimer's disease
Bostick, J. W.; Connerly, T. J.; Thron, T.; Needham, B. D.; de Castro Fonseca, M.; Kaddurah-Daouk, R.; Knight, R.; Mazmanian, S. K.
10.1101/2024.05.07.593011 — microbiology — Posted on 2024-05-08
3679 STECode: an automated virulence barcode generator to aid clinical and public health risk assessment of Shiga toxin-producing Escherichia coli
Sim, E. M.; Fong, W.; Suster, C.; Agius, J. E.; Chandra, S.; Suliman, B.; Wang, Q.; Ngo, C.; Finemore, C.; Chen, S. C.-A.; Basile, K.; Sintchenko, V.
10.1101/2024.05.07.593058 — microbiology — Posted on 2024-05-08
3681 Generating gnotobiotic bivalves: a new method on Manila clam (Ruditapes philippinarum)
Gallo, M.; Quagliariello, A.; Dalla Rovere, G.; Maietti, F.; Cardazzo, B.; Peruzza, L.; Bargelloni, L.; Martino, M. E.
10.1101/2024.05.08.593140 — microbiology — Posted on 2024-05-08
3683 Function and contribution of two putative Enterococcus faecalis glycosaminoglycan degrading enzymes to bacteremia and catheter-associated urinary tract infection
Johnson, A. O.; Shipman, B. M.; Hunt, B. C.; Learman, B. S.; Brauer, A. L.; Zhou, S. P.; Hageman Blair, R.; De Nisco, N. J.; Armbruster, C. E.
10.1101/2024.05.08.593205 — microbiology — Posted on 2024-05-08
3685 Modelling the gut microbiota of children with malnutrition: in vitro models reveal differences in fermentability of widely consumed carbohydrates
Ahn-Jarvis, J.; Corbin, K. R.; Harris, S. C.; Rey, P.; Olupot-Olupot, P.; Calder, N.; Walsh, K.; Maitland, K.; Frost, G.; Warren, F.
10.1101/2024.05.08.593150 — microbiology — Posted on 2024-05-08
3686 Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin
Berndsen, Z. T.; Akhtar, M.; Thapa, M.; Vickers, T. J.; Schmitz, A.; Torres, J.; Kumar, P.; Khatoon, N.; Sheikh, A.; Hamrick, M.; Diedrich, J.; Martinez-Bartolome, S.; Garrett, P.; Yates, J.; Turner, J.; Laird, R. M.; Porter, C. K.; Poly, F.; Copps, J.; Ellebedy, A.; Ward, A.; Fleckenstein, J. M.
10.1101/2024.05.08.593125 — microbiology — Posted on 2024-05-08
3687 autoMEA: Machine learning-based burst detection for multi-electrode array datasets
Hernandes, V.; Heuvelmans, A. M.; Gualtieri, V.; Meijer, D. H.; van Woerden, G. M.; Greplova, E.
10.1101/2024.05.08.593078 — neuroscience — Posted on 2024-05-08
3689 Effects of HMGCR deficiency on skeletal muscle development
Gunasekaran, M.; Littel, H. R.; Wells, N. M.; Turner, J.; Campos, G.; Venigalla, S.; Estrella, E. A.; Ghosh, P. S.; Daugherty, A. L.; Stafki, S. A.; Kunkel, L. M.; Foley, A. R.; Donkervoort, S.; Bonnemann, C. G.; Toledo Bravo de Laguna, L.; Nascimento, A.; Natera de Benito, D.; Draper, I.; Bruels, C. C.; Pacak, C. A.; Kang, P. B.
10.1101/2024.05.06.591934 — developmental biology — Posted on 2024-05-08
3690 Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson's disease
Nygaard, A. H.; Schorling, A. L.; Abay-Norgaard, Z. C.; Hanninen, E.; Li, Y.; Santoja, A.; Rathore, G. S.; Salvador, A.; Rusimbi, C. L.; Zhang, Y.; Kirkeby, A.
10.1101/2024.05.08.593131 — developmental biology — Posted on 2024-05-08
3691 Topological data analysis of pattern formation of human induced pluripotent stem cell colonies
Hartsock, I.; Park, E.; Toppen, J.; Bubenik, P.; Dimitrova, E. S.; Kemp, M. L.; Cruz, D. A.
10.1101/2024.05.07.592985 — developmental biology — Posted on 2024-05-08
3693 Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects
Bozon, K.; Cuny, H.; Sheng, D. Z.; Martin, E. M.; Young, P.; Humphreys, D. T.; Dunwoodie, S. L.
10.1101/2024.05.07.592899 — developmental biology — Posted on 2024-05-08
3695 Adaptation of pain-related projection neurons in acute but not chronic pain
Title, B.; Velasco, E.; Engelmayer, N. M.; Rayi, P. R.; Yanai, R.; Hart, S.; Katz, B.; Lev, S.; Yarom, Y.; Binshtok, A. M.
10.1101/2024.05.06.592712 — neuroscience — Posted on 2024-05-08
3698 Benchmarking methods for mapping functional connectivity in the brain
Liu, Z.-Q.; Luppi, A. I.; Hansen, J. Y.; Tian, Y. E.; Zalesky, A.; Yeo, B. T. T.; Fulcher, B. D.; Misic, B.
10.1101/2024.05.07.593018 — neuroscience — Posted on 2024-05-08
3700 THE NEURONAL ARCHITECTURE OF AUTONOMIC DYSREFLEXIA
Soriano, J. E.; Hudelle, R.; Mahe, L.; Gautier, M.; Teo, Y. Y.; Skinnider, M. A.; Laskaratos, A.; Ceto, S.; Kathe, C.; Hutson, T.; Charbonneau, R.; Girgis, F.; Casha, S.; Rimok, J.; Tso, M.; Larkin-Kaiser, K.; Hankov, N.; Gandhi, A.; Amir, S.; Kang, X.; Vyza, Y.; Martin-Moraud, E.; Lacour, S.; Demesmaeker, R.; Asboth, L.; Barraud, Q.; Anderson, M. A.; Bloch, J.; Squair, J. W.; Phillips, A. A.; Courtine, G.
10.1101/2024.05.06.592781 — neuroscience — Posted on 2024-05-08
3701 Non-Invasive Brain Mapping Localizes Essential Language Function in Surgical Glioma Patients
Muir, M.; Noll, K.; Prinsloo, S.; Michener, H.; Asman, P.; Traylor, J.; Kumar, V.; Ene, C.; Liu, H.-L.; Prabhu, S.
10.1101/2024.05.06.592752 — neuroscience — Posted on 2024-05-08
3702 Viral mimicry and memory deficits upon microglial deletion of ATRX
Shafiq, S.; Ghahramani, A.; Mansour, K.; Pena-Ortiz, M.; Sunstrum, J. K.; Jiang, Y.; Rowland, M. E.; Inoue, W.; Berube, N. G.
10.1101/2024.05.07.592875 — neuroscience — Posted on 2024-05-08
3704 Closed-loop modulation of remote hippocampal representations with neurofeedback
Coulter, M. E.; Gillespie, A. K.; Chu, J. P.; Denovellis, E. L.; Nguyen, T. T. K.; Liu, D.; Wadhwani, K.; Sharma, B.; Wang, K.; Deng, X.; Eden, U.; Kemere, C.; Frank, L. M.
10.1101/2024.05.08.593085 — neuroscience — Posted on 2024-05-08
3705 Stochastic growth and selective stabilization generate stereotyped dendritic arbors
Shi, R.; Ho, X. Y.; Tao, L.; Taylor, C. A.; Zhao, T.; Zou, W.; Lizzappi, M.; Eichel, K.; Shen, K.
10.1101/2024.05.08.591205 — neuroscience — Posted on 2024-05-08
3706 Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero
Perdue, M. V.; Ghasoub, M.; Long, M.; DeMayo, M. M.; Bell, T. K.; McMorris, C. A.; Dewey, D.; Gibbard, W. B.; Tortorelli, C.; Harris, A. D.; Lebel, C.
10.1101/2024.05.06.592786 — neuroscience — Posted on 2024-05-08
3707 A common computational and neural anomaly across mouse models of autism
Noel, J.-P.; Balzani, E.; Acerbi, L.; Benson, J.; The International Brain Laboratory (IBL), ; Savin, C.; Angelaki, D.
10.1101/2024.05.08.593232 — neuroscience — Posted on 2024-05-08
3713 Multivalent Targeting of Blood-Brain Barrier LRP1 for Neurovascular Recovery Therapy for Alzheimer s Disease
Chen, J.; Pan, X.; Duro Castano, A.; Cai, H.; Guo, B.; Liu, X.; Yu, Y.; Lui, S.; Luo, K.; Ke, B.; Ruiz-Perez, L.; Wei, X.; Gong, Q.; Tian, X.; Battaglia, G.
10.1101/2024.05.06.592767 — neuroscience — Posted on 2024-05-08
3716 Exercising with virtual reality is potentially better for the working memory and positive mood than cycling alone
Ochi, G.; Ohno, K.; Kuwamizu, R.; Yamashiro, K.; Fujimoto, T.; Ikarashi, K.; Kodama, N.; Onishi, H.; Sato, D.
10.1101/2024.05.07.593030 — neuroscience — Posted on 2024-05-08
3717 Widespread neural reorganization related to expertise in reading visual Braille
Cerpelloni, F.; Van Audenhaege, A.; Matuszewski, J.; Gau, R.; Battal, C.; Falagiarda, F.; Op de Beeck, H.; Collignon, O.
10.1101/2024.05.08.593104 — neuroscience — Posted on 2024-05-08
3719 Cadherin 4 assembles a family of color-selective retinal circuits that respond to light offset.
Olguin, A. G. R.; Rochon, P.-L.; Theriault, C.; Brown, T.; Cayouette, M.; Cook, E. P.; Krishnaswamy, A.
10.1101/2024.05.08.593219 — neuroscience — Posted on 2024-05-08
3720 Resting state brain network segregation is associated with walking speed and working memory in older adults
Sato, S. D.; Shah, V. A.; Fettrow, T.; Hall, K. G.; Tays, G. D.; Cenko, E.; Roy, A.; Clark, D. J.; Ferris, D. P.; Hass, C. J.; Manini, T. M.; Seidler, R. D.
10.1101/2024.05.07.592861 — neuroscience — Posted on 2024-05-08
3721 Hierarchical model of human brain oscillations
Myrov, V.; Suleimanova, A.; Knapic, S.; Liu, W.; Partanen, P.; Vesterinen, M.; Palva, S.; Palva, J. M.
10.1101/2024.05.08.593146 — neuroscience — Posted on 2024-05-08
3729 Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice
Sailor-Longsworth, E. J.; Lutze, R. D.; Ingersoll, M. A.; Kelmann, R. G.; Ly, K.; Currier, D.; Chen, T.; Zuo, J.; Teitz, T.
10.1101/2024.05.06.592815 — neuroscience — Posted on 2024-05-08
3732 α-Synuclein Conformations in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies
Kannarkat, G. T.; Zack, R.; Skrinak, R. T.; Morley, J. F.; Davila-Rivera, R.; Arezoumandan, S.; Dorfman, K.; Luk, K.; Wolk, D. A.; Weintraub, D.; Tropea, T. F.; Lee, E. B.; Xie, S. X.; Chandrasekaran, G.; Lee, V. M.-Y.; Irwin, D.; Akhtar, R. S.; Chen-Plotkin, A.
10.1101/2024.05.07.593056 — neuroscience — Posted on 2024-05-08
3733 Resiliency to Alzheimer's disease neuropathology can be distinguished from dementia using cortical astrogliosis imaging
Barsoum, S.; Latimer, C. S.; Nolan, A.; Barrett, A.; Chang, K.; Troncoso, J.; Keene, C. D.; Benjamini, D.
10.1101/2024.05.06.592719 — neuroscience — Posted on 2024-05-08
3734 Pharmacological HDAC3 inhibition alters memory updating in young and old mice
Smies, C. W.; Bellfy, L.; Wright, D. S.; Bennetts, S. S.; Urvan, M. W.; Brunswick, C. A.; Shu, G.; Kwapis, J. L.
10.1101/2024.05.08.593015 — neuroscience — Posted on 2024-05-08
3735 Functional resilience of the neural visual recognition system post-pediatric occipitotemporal resection
Granovetter, M. C.; Maallo, A. M. S.; Ling, S.; Robert, S.; Freud, E.; Patterson, C.; Behrmann, M.
10.1101/2024.05.08.592792 — neuroscience — Posted on 2024-05-08
3736 Data-driven analysis identifies female-specific social modulation deficit after chronic social defeat stress
Schuler, H.; Eid, R. S.; Wu, S.; Tse, Y.-C.; Cvetkovska, V.; Lopez, J.; Quinn, R.; Zhou, D.; Meccia, J.; Dion-Albert, L.; Menard, C.; Bennett, S. N.; Pena, C. J.; Bagot, R. C.
10.1101/2024.05.08.593167 — neuroscience — Posted on 2024-05-08
3737 Cell-surface receptor-mediated regulation of synaptic organelle distribution controls dendritic spine maturation
Verpoort, B.; Amado, L.; Vandensteen, J.; Leysen, E.; Dascenco, D.; Vandenbempt, J.; Lemmens, I.; Wauman, J.; Vennekens, K.; Escamilla-Ayala, A.; Freitas, A. C. N.; Voets, T.; Munck, S.; Tavernier, J.; de Wit, J.
10.1101/2024.05.08.592949 — neuroscience — Posted on 2024-05-08
3738 Effect of muscarinic blockade on the speed of attention shifting and learning
Thiele, A.; McDonald Milner, A.; Hall, C.; Mayhew, L.; Carter, A.; Sanjeev, S.
10.1101/2024.05.08.593141 — neuroscience — Posted on 2024-05-08
3742 Flp-recombinase mouse line for genetic manipulation of ipRGCs
Contreras, E.; Liang, C.; Mahoney, H.; Javier, J.; Luce, M.; Labastida Medina, K.; Bozza, T.; Schmidt, T. M.
10.1101/2024.05.06.592761 — neuroscience — Posted on 2024-05-08
3744 Sex differences in change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex
Durand-de Cuttoli, R.; Issler, O.; Yakubov, B.; Jahan, N.; Abid, A.; Kasparov, S.; Granizo, K.; Ahmed, S.; Russo, S. J.; Nestler, E. J.; Sweis, B. M.
10.1101/2024.05.08.592609 — neuroscience — Posted on 2024-05-08
3746 A novel critic signal in identified midbrain dopaminergic neurons of mice training inoperant tasks
Matsumoto, J.; Oberto, V.; Pompili, M. N.; Todorova, R.; Papaleo, F.; Nishijo, H.; Venance, L.; Vandecasteele, M.; Wiener, S. I.
10.1101/2024.05.06.592735 — neuroscience — Posted on 2024-05-08
3748 Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology
Park, S.; Noblett, N.; Pitts, L.; Colavita, A.; Wehman, A. M.; Jin, Y.; Chisholm, A. D.
10.1101/2024.05.07.591898 — neuroscience — Posted on 2024-05-08
3752 Cortex Folding by Combined Progenitor Expansion and Adhesion-Controlled Neuronal Migration
Chun, S. H.; Diaz Almeida, D. S.; Ivilinov Todoro, M.; Straub, T.; Ruff, T.; Shao, W.; Yang, J.; Seyit-Bremer, G.; Shen, Y.-R.; Erturk, A.; del Toro, D.; Shi, S.; Klein, R.
10.1101/2024.05.08.593109 — neuroscience — Posted on 2024-05-08
3756 Prefrontal 5α-reductase 2 mediates male-specific acute stress response
Cadeddu, R.; Braccagni, G.; Floris, G.; Branca, C.; Corridori, E.; Salviati, S.; Sanchez, P.; Santovito, L. S.; Torres, J. M.; Ortega, E.; Pinna, G.; Moos, P. J.; Scheggi, S.; Bortolato, M.
10.1101/2024.05.07.593076 — neuroscience — Posted on 2024-05-08
3758 Communicating mass spectrometry quality information in mzQC with Python, R, and Java
Bielow, C.; Hoffmann, N.; Jimenez-Morales, D.; Van Den Bossche, T.; Vizcaino, J. A.; Tabb, D. L.; Bittremieux, W.; Walzer, M.
10.1101/2024.05.06.592686 — bioinformatics — Posted on 2024-05-08
3759 This microtubule does not exist: Super-resolution microscopy image generation by a diffusion model
Saguy, A.; Nahimov, T.; Lehrman, M.; Gomez-de-Mariscal, E.; Hidalgo-Cenalmor, I.; Alalouf, O.; Henriques, R.; Shechtman, Y.
10.1101/2023.07.06.548004 — bioengineering — Posted on 2024-05-08
3765 Evolutionary analysis of paired box gene family and biological function exploration of Lr.Pax7 in lamprey (Lethenteron reissneri)
Han, Y.; Liu, X.; Nurmamat, A.; Yan, Z.; Jiang, Y.; Guan, H.; Zhou, Y.; Min, X.; Zhuang, R.; Zhang, S.; Li, D.; Pang, Y.; Zhao, L.
10.1101/2024.05.06.592610 — evolutionary biology — Posted on 2024-05-08
3766 Species interactions and food-web context drive temperature-dependent prey evolution
Han, Z.-Y.; Yuan, Y.; DeWitt, K.; Yammine, A.; Wieczynski, D. J.; Onishi, M.; Gibert, J. P.
10.1101/2024.05.06.592770 — ecology — Posted on 2024-05-08
3769 The utility of whole-genome sequencing to identify likely transmission pairs for pathogens with slow and variable evolution
Wood, A. J.; Benton, C. H.; Delahay, R. J.; Marion, G.; Palkopoulou, E.; Pooley, C. M.; Kao, R. R.
10.1101/2024.05.06.592672 — ecology — Posted on 2024-05-08
3770 Biological mechanisms are necessary to improve projections of species range shifts
Van der Meersch, V.; Armstrong, E.; Mouillot, F.; Duputie, A.; Davi, H.; Saltre, F.; Chuine, I.
10.1101/2024.05.06.592679 — ecology — Posted on 2024-05-08
3772 Native Korean wild mice (Mus musculus): molecular phylogeny and morphometrics
Kim, D.; Oh, J.; Oh, J. G.; Yang, H.-Y.; Kim, G.-J.; Lee, T.-H.; Lee, B.-G.; Park, C.; Nam, D.-H.
10.1101/2024.05.06.592665 — zoology — Posted on 2024-05-08
3773 Functional and multi-omic aging rejuvenation with GLP-1R agonism
Huang, J.; Kwok, A. J.; Li, J. C. Y.; Chiu, C. L. H.; Ip, B. Y. M.; Tung, L. Y.; Zheng, X.; Chow, H. T.; Lo, M. P. S.; Li, Z.; Chan, R. C. H.; Lin, N.; Wang, Z.; Wang, M.; Yan, L. Y. C.; Chan, D. C. W.; Wu, W. K. K.; Chow, H.-M.; Lin, W.-J.; Tang, Y.; Ng, B. W.-L.; Wong, S. H.; Leung, T. W.; Mok, V. C. T.; Ko, H.
10.1101/2024.05.06.592653 — systems biology — Posted on 2024-05-08
3777 Semaglutide interferes with postnatal growth in a diet-dependent manner
Joly, A.; Rebiffe, L.; Dusabyinema, Y.; Dellinger, J.; Leulier, F.; De Vadder, F.
10.1101/2024.05.06.592704 — physiology — Posted on 2024-05-08
3781 Maroon rice genomic diversity reflects 350 years of colonial history
van de Loosdrecht, M. S.; Pinas, N. M.; Tjoe Awie, J. R.; Becker, F. F. M.; Maat, H.; van Velzen, R.; van Andel, T.; Schranz, M. E.
10.1101/2024.05.06.592698 — genomics — Posted on 2024-05-08
3782 GenomicLinks: Deep learning predictions of 3Dchromatin loops in the maize genome
Schlegel, L.; Bhardwaj, R.; Shahryary, Y.; Demirtürk, D.; Marand, A. P.; Schmitz, R. J.; Johannes, F.
10.1101/2024.05.06.592633 — genomics — Posted on 2024-05-08
3785 Recurrent drought increases grassland community seasonal synchrony
Mueller, L. M.; Bahn, M.; Weidle, M.; Leitinger, G.; in 't Zandt, D.
10.1101/2024.01.29.577778 — ecology — Posted on 2024-05-08
3786 TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development
Doganli, C.; Baird, D. A.; Ali, Y.; Thomsen, O. K.; Audain, E.; Jessen, L.; Truelsen, P. M.; Mogensen, J. B.; Holm, M. S.; Apolinova, K.; Butto, L.; Diamanti, M.; Fialova, J. L.; Wade, E. M.; Robertson, S. P.; Pedersen, L. B.; Argiro, L. B.; Lescroart, F.; Hitz, M.-P.; Christensen, S. T.; Larsen, L. A.
10.1101/2024.05.06.592628 — developmental biology — Posted on 2024-05-08
3787 Theca cell mechanics and tissue pressure regulate mammalian ovarian folliculogenesis
Biswas, A.; Lou, Y.; Ng, B. H.; Tomida, K.; Darpe, S.; Wu, Z.; Lu, T. B.; Bonne, I.; Chan, C. J.
10.1101/2024.05.06.592641 — developmental biology — Posted on 2024-05-08
3791 The Brain Image Library: A Community-Contributed Microscopy Resource for Neuroscientists
Kenney, M.; Vasylieva, I.; Hood, G.; Cao-Berg, I.; Tuite, L.; Laghaei, R.; Smith, M. C.; Watson, A. M.; Ropelewski, A. J.
10.1101/2023.12.22.573024 — neuroscience — Posted on 2024-05-08
3798 Insecticide resistance and its intensity in urban Anopheles arabiensis in Kisumu City, Western Kenya: Implications for malaria control in urban areas
Machani, M. G.; Nzioki, I.; Onyango, S.; Onyango, B.; Githure, J.; Atieli, H.; Wang, C.; Lee, M.-C.; Githeko, A.; Afrane, Y.; Ochomo, E.; Yan, G.
10.1101/2024.05.06.592663 — ecology — Posted on 2024-05-08
3799 Analysis of auxin responses in the fern Ceratopteris richardii identifies tissue ontogeny as a major determinant for response properties
Woudenberg, S.; Dipp Alvarez, M.; Rienstra, J.; Levitsky, V.; Mironova, V.; Scarpella, E.; Kuhn, A.; Weijers, D.
10.1101/2024.05.03.592339 — plant biology — Posted on 2024-05-08
3802 Profiling genetically driven alternative splicing across the Indonesian Archipelago
Ibeh, N.; Kusuma, P.; Crenna-Darusallam, C.; Malik, S. G.; Sudoyo, H.; McCarthy, D. J.; Gallego Romero, I.
10.1101/2024.05.07.593052 — genomics — Posted on 2024-05-08
3803 Correlating phylogenetic and functional diversity of the nod-free but nodulating Bradyrhizobium phylogroup
Ling, L.; Camuel, A.; Wang, S.; Wang, X.; Liao, T.; Tao, J.; Lin, X.; Nouwen, N.; Giraud, E.; Luo, H.
10.1101/2023.06.14.544914 — genomics — Posted on 2024-05-08
3807 Unlocking the soundscape of coral reefs with artificial intelligence: pretrained networks and unsupervised learning win out
Williams, B.; Balvanera, S. M.; Sethi, S. S.; Lamont, T. A. C.; Jompa, J.; Prasetya, M.; Richardson, L.; Weschke, E.; Hoey, A.; Beldade, R.; Mills, S. C.; Haguenauer, A.; Zuberer, F.; Simpson, S. D.; Curnick, D.; Jones, K. E.
10.1101/2024.02.02.578582 — ecology — Posted on 2024-05-08
3810 Acinetobacter baumannii represses type VI secretion system through an Mn2+-dependent sRNA-mediated regulation
Bhowmik, S.; Pathak, A.; Devnath, K.; Sett, A.; Pandey, S.; Jyoti, N.; Bhando, T.; Akhter, J.; Chugh, S.; Singh, R.; Sharma, T. K.; Pathania, R.
10.1101/2022.07.30.502137 — microbiology — Posted on 2024-05-08
3811 IL-17A-mediated alterations in gut microbiota composition particularly changes in Prevotella abundance, impact Treg function in CNS Autoimmunity
Shahi, S. K.; Ghimire, S.; Jensen, S. N.; Lehman, P.; Rux, A. G.; Turner, T.-A.; Borcherding, N.; Gibson-Corley, K.; Ganesan, S. M.; Karandikar, N. J.; Mangalam, A. K.
10.1101/2022.04.22.489206 — immunology — Posted on 2024-05-08
3813 NEK1 modulates neurite outgrowth in motor neurons through coordinating retromer formation
Huang, X.; Oses, J. A.; Kawaguchi, R.; Perrault, L.; Frost, D.; Chen, K.; Guo, F.; Zhang, B.; Zhao, P.; Ho, T. S.-y.; Pandey, R.; Geschwind, D. H.; Burlingame, A.; Woolf, C.
10.1101/2024.05.06.592854 — neuroscience — Posted on 2024-05-08
3815 Oncogenic KRAS Mutations Confer a Unique Mechanotransduction Response to Peristalsis in Colorectal Cancer Cells
Clevenger, A. J.; Collier, C. A.; Gorley, J. P. M.; McFarlin, M. K.; Solberg, S. C.; Kopetz, S.; Stratman, A. N.; Raghavan, S.
10.1101/2024.05.07.593070 — bioengineering — Posted on 2024-05-08
3816 Self-Assembled Monolayer Transporters Enable Reagentless Analysis of Small Molecule Analytes
Flynn, C. D.; Riordan, K. T.; Young, T. L.; Chang, D.; Wu, Z.; Isaacson, S. E.; Yousefi, H.; Das, J.; Kelley, S. O.
10.1101/2024.05.07.592958 — bioengineering — Posted on 2024-05-08
3819 Identification and validation of drugs for repurposing in Glioblastoma: a computational and experimental workflow
Gonzalez, N.; Perez Kuper, M.; Garcia Fallit, M.; Pena Agudelo, J.; Nicola Candia, A.; Suarez Velandia, M.; Videla-Richardson, G.; Candolfi, M.
10.1101/2024.04.29.589520 — cancer biology — Posted on 2024-05-08
3821 Induction of the aggresome and insoluble tau aggregation using an optogenetic tool
Sakuragi, S.; Uchida, T.; Kato, N.; Zhao, B.; Hattori, A.; Sakata, Y.; Soeda, Y.; Takashima, A.; Yoshimura, H.; Matsumoto, G.; Bannai, H.
10.1101/2024.05.07.592868 — biophysics — Posted on 2024-05-08
3823 Machine learning models can identify individuals based on a resident oral bacteriophage family
Mahmoudabadi, G.; Homyk, K.; Catching, A.; Mahmoudabadi, A.; Foley, H. B.; Tadmor, A. D.; Phillips, R.
10.1101/2024.05.06.592821 — bioinformatics — Posted on 2024-05-08
3825 Assessing sprint technique with shoe-mounted inertial sensors
Pla, G. A.; Martini, D. N.; Potter, M. V.; Hoogkamer, W.; Cain, S. M.
10.1101/2024.05.06.592662 — bioengineering — Posted on 2024-05-08
3826 Kinases in motion: impact of protein and small molecule interactions on kinase conformations
Kugler, V.; Schwaighofer, S.; Feichtner, A.; Enzler, F.; Fleischmann, J.; Strich, S.; Schwarz, S.; Wilson, R.; Tschaikner, P.; Troppmair, J.; Sexl, V.; Meier, P.; Kaserer, T.; Stefan, E.
10.1101/2024.01.11.575270 — biochemistry — Posted on 2024-05-08
3827 Spirolactone, an unprecedented antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
Yang, Z.; Qiao, Y.; Strobech, E.; Morth, J. P.; Walther, G.; Jorgensen, T. S.; Peschel, G.; Rosenbaum, M. A.; Previtali, V.; Clausen, M. H.; Lukassen, M. V.; Gotfredsen, C. H.; Kurzai, O.; Weber, T.; Ding, L.
10.1101/2024.04.17.589928 — biochemistry — Posted on 2024-05-08
3829 Persistent Decision-Making in Mice, Monkeys, and Humans
Laurie, V.-J.; Shourkeshti, A.; Chen, C. S.; Herman, A. B.; Grissom, N. M.; Ebitz, R. B.
10.1101/2024.05.07.592970 — animal behavior and cognition — Posted on 2024-05-08
3831 Developmental editing control of mRNA ND7 involves KREH2 helicase-dependent gRNA selection and proposed RNA structure in Trypanosoma brucei
Meehan, J.; Ivens, A.; Grote, S.; Rodshagen, T.; Chen, Z.; Goode, C.; Sharma, S. K.; Kumar, V.; Frese, A.; Goodall, Z.; McCleskey, L.; Sechrist, R.; Zeng, L.; Savill, N. J.; Rouskin, S.; Schnaufer, A.; McDermott, S.; Cruz-Reyes, J.
10.1101/2024.05.06.592425 — molecular biology — Posted on 2024-05-08
3835 Electromagnetic Modeling within a Microscopically Realistic Brain - Implications for Brain Stimulation
Qi, Z.; Noetscher, G. M.; Miles, A.; Weise, K.; Knosche, T.; Cadman, C. R.; Potashinsky, A. R.; Liu, K.; Wartman, W. A.; Nunez Ponasso, G. C.; Bikson, M.; Lu, H.; Deng, Z.-D.; Nummenmaa, A.; Makaroff, S. N.
10.1101/2024.04.04.588004 — neuroscience — Posted on 2024-05-08
3838 Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior
Pennington, Z. T.; LaBanca, A. R.; Sompolpong, P.; Abdel-Raheim, S. D.; Ko, B.; Christenson Wick, Z.; Feng, Y.; Dong, Z.; Francisco, T. R.; Bacon, M. E.; Chen, L.; Fulton, S. L.; Maze, I.; Shuman, T.; Cai, D. J.
10.1101/2023.02.27.530077 — neuroscience — Posted on 2024-05-08
3839 Afferent projections to the Calca/CGRP-expressing parabrachial neurons in mice
Korkutata, M.; De Luca, R.; Fitzgerald, B.; Arrigoni, E.; Scammell, T. E.
10.1101/2024.05.07.593004 — neuroscience — Posted on 2024-05-08
3840 The vast majority of somatic mutations in plants are layer-specific
Goel, M.; Campoy, J. A.; Krause, K.; Baus, L. C.; Sahu, A.; Sun, H.; Walkemeier, B.; Marek, M.; Beaudry, R.; Ruiz, D.; Huettel, B.; Schneeberger, K.
10.1101/2024.01.04.573414 — genomics — Posted on 2024-05-08
3842 Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids
Cao, X.; Wu, X.; Zhao, L.; Zheng, J.; Jin, X.; Hao, X.; Winderickx, J.; Liu, S.; Chen, L.; Liu, B.
10.1101/2023.09.27.559647 — cell biology — Posted on 2024-05-08
3843 Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation
Zeeshan, M.; Rashpa, R.; Ferguson, D. J.; Mckeown, G.; Nugmanova, R.; Subodhi, A. K.; Beyeler, R.; Pashley, S. L.; Markus, R.; Brady, D.; Roques, M.; Bottrill, A. R.; Fry, A. M.; Pain, A.; vaughan, s.; Holder, A. A.; Tromer, E. C.; Brochet, M.; Tewari, R.
10.1101/2024.02.05.578160 — cell biology — Posted on 2024-05-08
3844 Disorder regulates homeostasis of extracytoplasmic proteins in streptococci
Rahman, M. M.; Zamakhaeva, S.; Rush, J. S.; Chaton, C. T.; Kenner, C. W.; Hla, Y. M.; Tsui, H.-C. T.; Winkler, M. E.; Korotkov, K. V.; Korotkova, N.
10.1101/2024.05.05.592596 — microbiology — Posted on 2024-05-08
3845 Buruli ulcer surveillance in south-eastern Australian possums: infection status, lesion mapping and internal distribution of Mycobacterium ulcerans
Hobbs, E. C.; Porter, J. L.; Lee, J. Y. H.; Loukopoulos, P.; Whiteley, P.; Skerratt, L. F.; Stinear, T. P.; Gibney, K. B.; Meredith, A. L.
10.1101/2024.05.07.592878 — microbiology — Posted on 2024-05-08
3846 Estrogen-regulated peptidergic input to gonadotropin-releasing hormone neurons from the lateral septal kisspeptin network
Szentkiralyi-Toth, S.; Gocz, B.; Takacs, S.; Sarvari, M.; Farkas, I.; Skrapits, K.; Rumpler, E.; Poliska, S.; Racz, G.; Matolcsy, A.; Ternier, G.; Fernandois, D.; Giacobini, P.; Prevot, V.; Colledge, W. H.; Wittmann, G.; Kadar, A.; Mohacsik, P.; Gereben, B.; Fekete, C.; Hrabovszky, E.
10.1101/2023.09.20.557932 — neuroscience — Posted on 2024-05-08
3847 Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
Perampalam, P.; MacDonald, J. I.; Zakirova, K.; Passos, D.; Wasif, S.; Ramos-Valdes, Y.; Hervieu, M.; Mehlen, P.; Rottapel, R.; Gibert, B.; Correa, R.; Shepherd, T.; Dick, F.
10.1101/2023.08.29.555435 — cancer biology — Posted on 2024-05-08
3852 Unlocking the soundscape of coral reefs with artificial intelligence: pretrained networks and unsupervised learning win out
Williams, B.; Belvanera, S. M.; Sethi, S. S.; Lamont, T. A. C.; Jompa, J.; Prasetya, M.; Richardson, L.; Weschke, E.; Hoey, A.; Beldade, R.; Mills, S. C.; Haguenauer, A.; Zuberer, F.; Simpson, S. D.; Curnick, D.; Jones, K. E.
10.1101/2024.02.02.578582 — ecology — Posted on 2024-05-08
3857 Interaction Between the Prefrontal and Visual Cortices Supports Subjective Fear
Taschereau-Dumouchel, V.; Cote, M.; Valevicius, D.; Manuel, S.; Cushing, C.; Cortese, A.; Kawato, M.; Lau, H.
10.1101/2023.10.23.562918 — neuroscience — Posted on 2024-05-08
3859 Brain Age Analysis and Dementia Classification using Convolutional Neural Networks trained on Diffusion MRI: Tests in Indian and North American Cohorts
Chattopadhyay, T.; Joshy, N. A.; Ozarkar, S. S.; Buwa, K. S.; Feng, Y.; Laltoo, E.; Thomopoulos, S. I.; Villalon-Reina, J. E.; Joshi, H.; Venkatasubramanian, G.; John, J. P.; Thompson, P. M.
10.1101/2024.02.04.578829 — neuroscience — Posted on 2024-05-08
3860 Experimental nerve block study on painful withdrawal reflex responses in humans
Thorell, O.; Mahns, D. A.; Otto, J.; Liljencrantz, J.; Svantesson, M.; Olausson, H.; Nagi, S. S.
10.1101/2023.09.04.556255 — neuroscience — Posted on 2024-05-08
3862 Socialization causes long-lasting behavioral changes
Gil-Marti, B.; Isidro-Mezcua, J.; Poza-Rodriguez, A.; Asti Tello, G. S.; Treves, G.; Turiegano, E.; Beckwith, E. J.; Martin, F. A.
10.1101/2024.04.25.591071 — neuroscience — Posted on 2024-05-08
3864 Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
Held, M.; Bisen, R. S.; Zandawala, M. M.; Chockley, A. S.; Balles, I. S.; Hilpert, S.; Liessem, S.; Cascino-Milani, F.; Ache, J. M.
10.1101/2023.09.14.557555 — neuroscience — Posted on 2024-05-08
3865 A molecularly distinct cell type in the midbrain regulates intermale aggression behaviors in mice
Li, C.-Y.; Miao, C.; Ge, Y.; Wu, J.; Gao, P.; Yin, S.; Zhang, P.; Tian, B.; Chen, W.; Chen, X.-Q.
10.1101/2023.10.19.562724 — neuroscience — Posted on 2024-05-08
3869 Sodium azide mutagenesis induces a unique pattern of mutations
Liu, C.; Frascarelli, G.; Stec, A. O.; Heinen, S.; Lei, L.; Wyant, S. R.; Legg, E.; Spiller, M.; Muehlbauer, G. J.; Smith, K. P.; Fay, J. C.; Morrell, P. L.
10.1101/2024.05.06.592067 — genomics — Posted on 2024-05-07
3871 Unraveling Genome- and Immunome-wide Genetic Diversity in Jaguars (Panthera onca): Implications for Targeted Conservation
Meissner, R.; Winter, S.; Elbers, J. P.; Plasil, M.; Futas, J.; Mohandesan, E.; Sharif, M. B.; Horin, P.; Prost, S.; Burger, P.
10.1101/2024.05.06.592690 — genomics — Posted on 2024-05-07
3874 Neuronal activation affects the organization and protein composition of the nuclear speckles
Szczepankiewicz, A. A.; Parobczak, K.; Zareba-Koziol, M.; Ruszczycki, B.; Bijata, M.; Trzaskoma, P.; Hajnowski, G.; Holm-Kaczmarek, D.; Wlodarczyk, J.; Wilczynski, G. M.; Redowicz, M. J.; Magalska, A.
10.1101/2024.03.25.586583 — cell biology — Posted on 2024-05-08
3875 Phylogeography of bar-tailed godwits: pre-LGM structure in Beringia and westward colonization of post-glacial Europe
Conklin, J. R.; Verkuil, Y. I.; Lefebvre, M. J. M.; Battley, P. F.; Bom, R. A.; Hassell, C. J.; ten Horn, J.; Tomkovich, P. S.; Warnock, N.; Piersma, T.; Fontaine, M. C.
10.1101/2024.04.22.590527 — evolutionary biology — Posted on 2024-05-08
3876 Seasonal effects of long-term warming on ecosystem function and bacterial diversity
Shinfuku, M. S.; Domeignoz-Horta, L. A.; Choudoir, M. J.; Frey, S.; Mitchell, M. F.; Ranjan, R.; DeAngelis, K. M.
10.1101/2023.08.14.553264 — ecology — Posted on 2024-05-08
3879 Kinase Suppressor of Ras 2 promotes self-renewal and clonogenicity of small-cell lung carcinoma
Huisman, D. H.; Chatterjee, D.; Svoboda, R. A.; Vieira, H. M.; Ireland, A. S.; Skupa, S.; Askew, J. W.; Frodyma, D. E.; Girard, L.; Fisher, K. W.; Kareta, M.; Minna, J.; Oliver, T. G.; Lewis, R. E.
10.1101/2022.02.11.480157 — cancer biology — Posted on 2024-05-08
3880 The Geometric Basis of Epithelial Convergent Extension
Brauns, F.; Claussen, N.; Lefebvre, M. F.; Wieschaus, E.; Shraiman, B. I.
10.1101/2023.05.30.542935 — biophysics — Posted on 2024-05-08
3881 Contact area and tissue growth dynamics shape synthetic juxtacrine signaling patterns
Dawson, J.; Bryant, A.; Jordan, T.; Bhikot, S.; Macon, S.; Walton, B.; Ajamu-Johnson, A.; Langridge, P. D.; Malmi-Kakkada, A. N.
10.1101/2023.07.12.548752 — biophysics — Posted on 2024-05-08
3882 AAV-DJ is Superior to AAV9 for Targeting Brain and Spinal Cord, and De-Targeting Liver Across Multiple Delivery Routes in Mice
Chauhan, M.; Daugherty, A. L.; Khadir, F. E.; Duzenli, O. F.; Hoffman, A.; Tinklenberg, J. A.; Kang, P. B.; Aslanidi, G.; Pacak, C. A.
10.1101/2024.05.06.592798 — molecular biology — Posted on 2024-05-07
3883 Repeated fasting events sensitize enhancers, transcription factor activity and gene expression to support augmented ketogenesis
Korenfeld, N.; Charni-Natan, M.; Bruse, J.; Goldberg, D.; Marciano-Anaki, D.; Rotaro, D.; Gorbonos, T.; Radushkevitz-Frishman, T.; Polizzi, A.; Nasereddin, A.; Bar-Shimon, M.; Fougerat, A.; Guillou, H.; Goldstein, I.
10.1101/2024.05.07.592891 — molecular biology — Posted on 2024-05-07
3884 Developmental editing control of mRNA ND7 involves KREH2 helicase-dependent gRNAselection and proposed RNA structure in Trypanosoma brucei
Meehan, J.; Ivens, A.; Grote, S.; Rodshagen, T.; Chen, Z.; Goode, C.; Sharma, S. K.; Kumar, V.; Frese, A.; Goodall, Z.; McCleskey, L.; Sechrist, R.; Zeng, L.; Savill, N. J.; Rouskin, S.; Schnaufer, A.; Cruz-Reyes, J.
10.1101/2024.05.06.592425 — molecular biology — Posted on 2024-05-07
3885 Mechanisms of RecA filament nucleation on ssDNA by the DprA protein
Bakhlanova, I.; Alekseev, A.; Yakunina, M.; Morozova, N.; Khodorkovskii, M.; Petukhov, M.; Baitin, D.
10.1101/2024.05.07.592916 — molecular biology — Posted on 2024-05-07
3886 Modulation of host signalling pathways reveal a major role for Wnt signalling in the maturation of Plasmodium falciparum liver schizonts
Kanyal, A.; van Gemert, G.-J.; Wu, H.; van der Starre, A.; de Wilt, J. H.; Bousema, T.; Sauerwein, R. W.; Bartfai, R.; Yang, A. S. P.
10.1101/2024.05.07.592925 — microbiology — Posted on 2024-05-07
3890 Viroporin activity from rotavirus nonstructural protein 4 induces intercellular calcium waves that contribute to pathogenesis
Gebert, J. T.; Scribano, F. J.; Engevik, K. A.; Philip, A. A.; Kawagishi, T.; Greenberg, H. B.; Patton, J. T.; Hyser, J. M.
10.1101/2024.05.07.592929 — microbiology — Posted on 2024-05-07
3891 Bacterial family-specific enrichment and functions of secretion systems in the rhizosphere
Fourie, A.; Lopez, J. L.; Sanchez-Gil, J. J.; Poppeliers, S. W. M.; de Jonge, R.; Dutilh, B. E.
10.1101/2024.05.07.592589 — microbiology — Posted on 2024-05-07
3892 Probiotic Lactobacilli activate Formyl-Peptide Receptor 2
Kretschmer, D.; Rosenstein, R.; Elsherbini, A.; Krismer, B.; OToole, P.; Gerlach, D.; Peschel, A.
10.1101/2024.05.07.592932 — microbiology — Posted on 2024-05-07
3893 A type II secreted subtilase from commensal rhizobacteria disarms the immune elicitor peptide flg22
Eastman, S.; Jiang, T.; Ficco, K.; Liao, C.; Jones, B.; Wen, S.; Olivas Biddle, Y.; Eyceoz, A.; Yatsishin, I.; Naumann, T. A.; Conway, J. M.
10.1101/2024.05.07.592856 — microbiology — Posted on 2024-05-07
3894 Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain
Dong, Q.; Harper, S.; McSpadden, E.; Son, S. S.; Allen, M.-M.; Lin, H.; Smith, R. C.; Metcalfe, C.; Burgo, V.; Woodson, C.; Sundararajan, A.; Rose, A.; McMillin, M.; Moran, D.; Little, J.; Mullowney, M. W.; Sidebottom, A. M.; Shen, A.; Fortier, L.-C.; Pamer, E. G.
10.1101/2024.05.06.592814 — microbiology — Posted on 2024-05-07
3897 Intraspecies warfare restricts strain coexistence in human skin microbiomes
Mancuso, C. P.; Baker, J.; Qu, E.; Tripp, A. D.; Balogun, I. O.; Lieberman, T.
10.1101/2024.05.07.592803 — microbiology — Posted on 2024-05-07
3899 Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei
Krasilnikova, M.; Marques, C. A.; Briggs, E. M.; Lapsley, C.; Hamilton, G.; Beraldi, D.; Crouch, K.; McCulloch, R.
10.1101/2024.05.07.592375 — microbiology — Posted on 2024-05-07
3900 Functional plasticity of HCO3- uptake and CO2 fixation in Cupriavidus necator H16
Panich, J.; Toppari, E.; Tejedor-Sanz, S.; Fong, B.; Dugan, E.; Chen, Y.; Petzold, C.; Zhao, Z.; Yoshikuni, Y.; Savage, D. F.; Singer, S. W.
10.1101/2024.05.07.593039 — synthetic biology — Posted on 2024-05-07
3902 Insulin regulates lymphatic endothelial function via palmitoylation
Gonzalez-Nieves, S.; Wei, X.; McQuillan, J.; Zhang, Q.; Zhang, J.; McGuffee, R. M.; Ford, D. A.; Love-Gregory, L.; Abumrad, N. A.; Gelman, A. E.; Semenkovich, C. F.; Cifarelli, V.
10.1101/2024.05.06.592341 — physiology — Posted on 2024-05-07
3916 COEXIST: Coordinated single-cell integration of serial multiplexed tissue images
Heussner, R. T.; Watson, C. F.; Eddy, C. Z.; Wang, K.; Cramer, E. M.; Creason, A. L.; Mills, G. B.; Chang, Y. H.
10.1101/2024.05.05.592573 — bioinformatics — Posted on 2024-05-07
3918 Spatial risk of disease transmission between wild bovids and livestock in Thailand
Horpiencharoen, W.; Marshall, J. C.; Muylaert, R. L.; John, R. S.; Hayman, D. T. S.
10.1101/2024.05.04.592526 — ecology — Posted on 2024-05-07
3921 Velocity-selective arterial spin labelling bolus duration measurements: Implications for consensus recommendations
Driver, I. D.; Chandler, H. L.; Patitucci, E.; Morgan, E. L.; Murphy, K.; Zappala, S.; Wise, R. G.; Germuska, M.
10.1101/2024.05.04.592549 — neuroscience — Posted on 2024-05-07
3922 Type-I interferons drive the gastrointestinal inflammatory response in a mouse model of Parkinsons disease
Waters, H.; Chen, S.; Vincan, E.; Flanagan, D. J.; Schwab, R. H. M.; Crack, P. J.; Taylor, J. M.
10.1101/2024.05.05.592614 — neuroscience — Posted on 2024-05-07
3923 An ultra-short-acting benzodiazepine in thalamic nucleus reuniens undermines fear extinction via intermediation of hippocamposeptal circuits
Cheung, H.; Yu, T.-Z.; Yi, X.; Wu, Y.-J.; Wang, Q.; Gu, X.; Xu, M.; Cai, M.; Wen, W.; Li, X.-N.; Liu, Y.-X.; Sun, Y.; Zheng, J.; Xu, T.-L.; Luo, Y.; Zhang, M.; Li, W.-G.
10.1101/2024.05.06.592637 — neuroscience — Posted on 2024-05-07
3924 Scheduled feeding improves sleep in a mouse model of Huntington's disease.
Chiem, E.; Zhao, K.; Dell'Angelica, D.; Ghiani, C.; Paul, K.; Colwell, C. S.
10.1101/2024.05.04.592428 — neuroscience — Posted on 2024-05-07
3925 State- and circuit-dependent opponent-processing of fear
Yau, J. O.-Y.; Li, A.; Abdallah, L.; Lisowski, L.; McNally, G. P.
10.1101/2024.05.06.592282 — neuroscience — Posted on 2024-05-07
3927 Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice
El-Awaisi, J.; Perrella, G.; Mayor, N.; Tinkova, V.; Cleary, S. J.; Grygielska, B.; Watson, S. P.; Dimitrov, J. D.; Brill, A.; Nicolson, P. L.; Kavanagh, D.; Kalia, N.; Rayes, J.
10.1101/2024.05.04.592537 — pathology — Posted on 2024-05-07
3930 Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins Using Fine-tuned Diffusion Models
Zhu, J.; Li, Z.; Zhang, B.; Zheng, Z.; Zhong, B.; Bai, J.; Wang, T.; Wei, T.; Yang, J.; Chen, H.-F.
10.1101/2024.05.05.592611 — bioinformatics — Posted on 2024-05-07
3931 Rapid radiation of a plant lineage sheds light on the assembly of dry valley biomes
Chen, Y.-P.; Sunojkumar, P.; Spicer, R. A.; Hodel, R. G.; Soltis, D.; Soltis, P. S.; Paton, A. J.; Sun, M.; Drew, B. T.; Xiang, C.-L.
10.1101/2024.05.05.592625 — evolutionary biology — Posted on 2024-05-07
3932 Macroevolutionary Constraint and Selection on Anti-Bat Moth Tails
Rubin, J.; Campbell, C. J.; Carvalho, A. P. S.; St. Laurent, R. A.; Crespo, G. I.; Pierson, T. L.; Guralnick, R. P.; Kawahara, A. Y.
10.1101/2024.05.05.590753 — evolutionary biology — Posted on 2024-05-07
3935 Dual α-globin and truncated erythropoietin receptor knock-in restores hemoglobin production in α-thalassemia major-derived hematopoietic stem and progenitor cells
Chu, S. N.; Soupene, E.; Wienert, B.; Yin, H.; Sharma, D.; McCreary, T.; Jia, K.; Homma, S.; Hampton, J. P.; Gardner, J. M.; Conklin, B. R.; MacKenzie, T. C.; Porteus, M. H.; Cromer, M. K.
10.1101/2023.09.01.555926 — molecular biology — Posted on 2024-05-07
3938 Mechanism, and treatment of anti-CV2/CRMP5 autoimmune pain
Martin, L.; Stratton, H. J.; Gomez, K.; Do, L.; Loya-lopez, S.; Tang, C.; Calderon-rivera, A.; Ran, D.; Nunn, V.; Bellampalli, S. S.; Francois-Moutal, L.; Dumaire, N. L. A.; Salih, L.; Luo, S.; Porreca, F.; Ibrahim, M.; Rogemond, V.; Honnorat, J.; Khanna, R.; Moutal, A.
10.1101/2024.05.04.592533 — neuroscience — Posted on 2024-05-07
3940 RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as viral replication factories
Kaundal, S.; Ramakrishnan, A.; Ayyar, B. V.; Shanker, S.; Kaur, G.; Crawford, S. E.; Pollet, J.; Stossi, F.; Estes, M. K.; Prasad, B. V. V.
10.1101/2023.08.24.554692 — biochemistry — Posted on 2024-05-07
3942 Proposed network of Marine Protected Areas supports larval dispersal and connectivity in the Eastern Mediterranean
Berenshtein, I.; Stern, N.; Tagar, A.; Morov, A.; Paris, C. B.; Lapidot, O.; Fredj, E.; Zaken, J.; Biton, E.
10.1101/2024.04.28.591505 — ecology — Posted on 2024-05-07
3943 Senescence of endplate osteoclasts induces sensory innervation and spinal pain
Pan, D.; Benkato, K. G.; Han, X.; Zheng, J.; Kumar, V.; Wan, M.; Zheng, J.; Cao, X.
10.1101/2023.10.26.564218 — cell biology — Posted on 2024-05-07
3944 Human cortical high-gamma power relates to movement speed and is disproportionately reduced after stroke
Haverland, B.; Timmsen, L. S.; Wolf, S.; Stagg, C. J.; Frontzkowski, L.; Oostenveld, R.; Feldheim, J.; Higgen, F. L.; Gerloff, C.; Schulz, R.; Schneider, T. R.; Schwab, B. C.; Quandt, F.
10.1101/2023.11.07.565934 — neuroscience — Posted on 2024-05-07
3945 Modeling and Simulation of Rat Non-Barrel Somatosensory Cortex. Part I: Modeling Anatomy
Reimann, M. W.; Bolanos Puchet, S.; Egas Santander, D.; Courcol, J.-D.; Arnaudon, A.; Coste, B.; Delemontex, T.; Devresse, A.; Dictus, H.; Dietz, A.; Ecker, A.; Favreau, C.; Ficarelli, G.; Gevaert, M.; Hernando, J. B.; Herttuainen, J.; Isbister, J. B.; Kanari, L.; Keller, D.; King, J. G.; Kumbhar, P.; Lapere, S.; Lazovskis, J.; Lu, H.; Ninin, N.; Pereira, F.; Planas, J.; Pokorny, C.; Riquelme, J. L.; Romani, A.; Shi, Y.; Smith, J. P.; Sood, V.; Srivastava, M.; Van Geit, W.; Vanherpe, L.; Wolf, M.; Levi, R.; Hess, K.; Schürmann, F.; Muller, E. B.; Ramaswamy, S.; Markram, H.
10.1101/2022.08.11.503144 — neuroscience — Posted on 2024-05-07
3946 Direct observation of the neural computations underlying a single decision
Steinemann, N. A.; Stine, G. M.; Trautmann, E. M.; Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.
10.1101/2022.05.02.490321 — neuroscience — Posted on 2024-05-07
3947 SLC13A2-transported citrate is a metabolic signal for PKM2 acetylation and degradation to suppress tumor growth
Xiong, J.; Hao, H.; Qin, M.; Shi, L.; Chen, H.; Liu, C.; Tang, Z.; An, D.; Yu, W.; He, D.; Shao, C.; Yuan, S.; Yu, H.
10.1101/2024.05.04.591017 — cancer biology — Posted on 2024-05-07
3948 AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer
Sardar, S.; McNair, C. M.; Ravindranath, L.; Chand, S. N.; Yuan, W.; Bogdan, D.; Welti, J.; Sharp, A.; Ryan, N. K.; Schiewer, M. J.; DeArment, E. G.; Janas, T.; Su, X. A.; Butler, L. M.; de Bono, J. S.; Frese, K.; Brooks, N.; Pegg, N.; Knudsen, K. E.; Shafi, A. A.
10.1101/2024.05.07.592966 — cancer biology — Posted on 2024-05-07
3949 Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts In Vitro to Tolerate High Levels of Somatic Mutations
Zhang, L.; Lee, M.; Hao, X.; Ehlert, J.; Chi, Z.; Jin, B.; Maslov, A. Y.; Barabasi, A.-L.; Hoeijmakers, J. H. J.; Edelmann, W.; Vijg, J.; Dong, X.
10.1101/2024.05.04.592535 — genomics — Posted on 2024-05-07
3950 The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1
Corfield, E. C.; Shadrin, A. A.; Frei, O.; Rahman, Z.; Lin, A.; Athanasiu, L.; Cevdet Akdeniz, B.; Tekin Filiz, T.; Hannigan, L.; Wootton, R. E.; Austerberry, C.; Hughes, A.; Tesli, M.; Westlye, L. T.; Stefansson, H.; Stefansson, K.; Njolstad, P. R.; Magnus, P.; Davies, N. M.; Appadurai, V.; Hemani, G.; Hovig, E.; Zayats, T.; Ask, H.; Reichborn-Kjennerud, T.; Andreassen, O. A.; Havdahl, A.
10.1101/2022.06.23.496289 — genetics — Posted on 2024-05-07
3951 The evolutionary history and functional specialization of microRNA genes in Arabidopsis halleri and A. lyrata
Pavan, F.; Azevedo Favory, J.; Lacoste, E.; Beaumont, C.; Louis, F.; Blassiau, C.; Cruaud, C.; Labadie, K.; Gallina, S.; Genete, M.; Kumar, V.; Kramer, U.; Adriano Batista, R.; Patiou, C.; Debacker, L.; Ponitzki, C.; Houze, E.; Durand, E.; Aury, J.-M.; Castric, V.; Legrand, S.
10.1101/2024.05.03.592357 — evolutionary biology — Posted on 2024-05-07
3956 A Decade in a Systematic Review: The Evolution and Impact of Cell Painting
Seal, S.; Trapotsi, M.-A.; Spjuth, O.; Singh, S.; Carreras-Puigvert, J.; Greene, N.; Bender, A.; Carpenter, A. E.
10.1101/2024.05.04.592531 — cell biology — Posted on 2024-05-07
3957 Parkinson's Disease-Linked Kir4.2 Mutation R28C Leads to Loss of Ion Channel Function
Chen, X.; Finol-Urdaneta, R. K.; Chen, M.; Sykes, A.; Gao, B.; Adams, D. J.; Mellick, G. D.; Ma, L.
10.1101/2024.05.05.592599 — cell biology — Posted on 2024-05-07
3959 Proteomic Profiling of Mesenchymal Stem Cell-Derived Extracellular Vesicles: Impact of Isolation Methods on Protein Cargo
Abyadeh, M.; Mirshahvaladi, S.; Assar Kashani, S.; A. Paulo, J.; Amirkhani, A.; Mehryab, F.; Seidi, H.; Moradpour, N.; Jodeiryjabarzade, S.; Mirzaei, M.; Gupta, V.; Shekari, F.; Hosseini Salekdeh, G.
10.1101/2024.05.06.592788 — cell biology — Posted on 2024-05-07
3960 Time-lapse Image Super-resolution Neural Network with Reliable Confidence Evaluation for Optical Microscopy
Qiao, C.; Liu, S.; Wang, Y.; Xu, W.; Geng, X.; Jiang, T.; Zhang, J.; Meng, Q.; Qiao, H.; Li, D.; Dai, Q.
10.1101/2024.05.04.592503 — biophysics — Posted on 2024-05-07
3962 The Mycobacterium lipid transporter MmpL3 is dimeric in detergent solution, SMALPs and reconstituted nanodiscs
Cioccolo, S.; Barritt, J.; Pollock, N.; Hall, Z.; Babuta, J.; Sridhar, P.; Just, A.; Morgner, N.; Dafforn, T. R.; Gould, I.; Byrne, B.
10.1101/2024.05.06.592688 — biophysics — Posted on 2024-05-07
3964 Rapid and Accurate Estimation of Genetic Relatedness Between Millions of Viral Genome Pairs Using MANIAC
Ndovie, W.; Havranek, J.; Koszucki, J.; Leconte, J.; Chindelevitch, L.; Adriaenssens, E. M.; Mostowy, R. J.
10.1101/2024.04.23.590796 — bioinformatics — Posted on 2024-05-07
3969 Hippocampal sharp wave ripples and coincident cortical ripples orchestrate human semantic networks
Mishra, A.; Akkol, S.; Espinal, E.; Markowitz, N.; Tostaeva, G.; Freund, E.; Mehta, A.; Bickel, S.
10.1101/2024.04.10.588795 — neuroscience — Posted on 2024-05-07
3971 Unraveling the Molecular Landscape of Uterine Fibroids, Insights into HMGA2 and Stem Cell Involvement
Paul, E. N.; Carpenter, T. J.; Pavliscak, L. A.; Bennett, A. Z.; Ochoa-Bernal, M. A.; Fazleabas, A. T.; Teixeira, J. M.
10.1101/2024.04.26.591351 — molecular biology — Posted on 2024-05-07
3973 Transcriptional Remodeling of the Stromal and Endothelial Microenvironment in MGUS to Multiple Myeloma Progression
Cenzano, I.; Cocera, M.; Bantan, A.; Larrayoz, M.; Vilas, A.; San-Martin, P.; Aguirre-Ruiz, P.; Alignani, D.; Lopez, A.; Minana, M.; Quilez Agreda, D.; Sancho Gonzalez, I.; Ruiz, J.; Lagani, V.; Tegner, J.; Martin-Subero, I.; Agirre, X.; Paiva, B.; Rodriguez-Otero, P.; Tamariz-Amador, L.-E.; San-Miguel, J.; Martinez-Climent, J. A.; Saez, B.; Hernaez, M.; Calvo, I. A.; Gomez-Cabrero, D.; Prosper, F.
10.1101/2024.04.24.589777 — cancer biology — Posted on 2024-05-07
3975 Mechanistic modelling of Mycobacterium Tuberculosis beta carbonic anhydrase 3 inhibitors
Manaithiya, A.; Bhowmik, R.; Ray, R.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.
10.1101/2024.04.30.591915 — bioinformatics — Posted on 2024-05-07
3981 Neuronal and oligodendroglial but not astroglial tau translates to in vivo tau-PET signals in primary tauopathies
Slemann, L.; Gnorich, J.; Hummel, S.; Bartos, L. M.; Klaus, C.; Kling, A.; Kusche-Palenga, J.; Kunte, S. T.; Kunze, L. H.; Englert, A. L.; Li, Y.; Vogler, L.; Katzdobler, S.; Palleis, C.; Bernhardt, A.; Jäck, A.; Zwergal, A.; Hopfner, F.; Romer, S.; Biechele, G.; Stocklein, S.; Bischof, G.; van Eimeren, T.; Drzezga, A.; Sabri, O.; Barthel, H.; Respondek, G.; Grimmer, T.; Levin, J.; Herms, J.; Paeger, L.; Willroider, M.; Beyer, L.; Hoglinger, G. U.; Roeber, S.; Franzmeier, N.; Brendel, M.
10.1101/2024.05.04.592508 — neuroscience — Posted on 2024-05-07
3982 The visuomotor transformations underlying defensive behaviors and hunting
Zhao, P.; Tong, Y.; Lazarte, I. P.; Khan, B.; Lam, T. K. C.; Semmelhack, J. L.
10.1101/2024.05.07.592863 — neuroscience — Posted on 2024-05-07
3984 The major nucleoid-associated protein WHIRLY1 promotes chloroplast development in barley
Krupinska, K.; Eirich, J.; Repnik, U.; Desel, C.; Saeid Nia, M.; Schmidt, A.; Voigt, U.; Bennewitz, B.; Bilger, W.; Finkemeier, I.; Hensel, G.
10.1101/2024.05.06.592765 — plant biology — Posted on 2024-05-07
3986 The assembly and annotation of two teinturier grapevine varieties, Dakapo and Rubired
Ritter, E. J.; Cochetel, N.; Minio, A.; Cousins, P.; Cantu, D.; Niederhuth, C.
10.1101/2024.05.03.592245 — genomics — Posted on 2024-05-07
3987 Gene-specific RNA homeostasis revealed by perturbation of coactivator complexes
Forouzanfar, F.; Plassard, D.; Furst, A.; Moreno, D.; Oliveira, K. A.; Reina-San-Martin, B.; Tora, L.; Molina, N.; Mendoza, M.
10.1101/2024.01.30.577960 — genomics — Posted on 2024-05-07
3991 Mast fruiting in a large tropical African legume tree provides evidence for the nutrient resource limitation hypothesis
Newbery, D. M.; Schwan, S.; Chuyong, G. B.; Neba, G. A.; Etta, C. E.; Norghauer, J. M.; Worbes, M.
10.1101/2023.04.03.535348 — ecology — Posted on 2024-05-07
3994 Mutations in Fibronectin Dysregulate Chondrogenesis in Skeletal Dysplasia
Dinesh, N. E. H.; Rousseau, J.; Mosher, D. F.; Strauss, M.; Mui, J.; Campeau, P. M.; Reinhardt, D. P.
10.1101/2023.12.22.573039 — cell biology — Posted on 2024-05-07
3995 CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies
Richard, J.; Sannier, G.; Zhu, L.; Prevost, J.; Marchitto, L.; Benlarbi, M.; Beaudoin-Bussieres, G.; Hongil, K.; Sun, Y.; Chatterjee, D. A.; Medjahed, H.; Bourassa, C.; Delgado, G.-G.; Dube, M.; Kirchhoff, F.; Hahn, B. H.; Kumar, P.; Kaufmann, D. E.; Finzi, A.
10.1101/2024.05.01.592003 — microbiology — Posted on 2024-05-07
3999 Remote automated delivery of mechanical stimuli coupled to brain recordings in behaving mice
Burdge, J.; Jhumka, A.; Ogundare, S.; Baer, N.; Fulton, S.; Bistis, B.; Foster, W.; Toussaint, A.; Li, M.; Morizawa, Y. M.; Yadessa, L.; Khan, A.; Delinois, A.; Mayiseni, W.; Loran, N.; Yang, G.; Abdus-Saboor, I.
10.1101/2024.05.06.592101 — neuroscience — Posted on 2024-05-07
4002 Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways
Batista, R. A.; Durand, E.; Mörchen, M.; Azevedo-Favory, J.; Simon, S.; Dubin, M.; Kumar, V.; Lacoste, E.; Cruaud, C.; Blassiau, C.; Barois, M.; Holl, A.-C.; Ponitzki, C.; Faure, N.; Marande, W.; Vautrin, S.; Fobis-Loisy, I.; Aury, J.-M.; Legrand, S.; Krämer, U.; Lagrange, T.; Vekemans, X.; Castric, V.
10.1101/2024.05.01.591913 — plant biology — Posted on 2024-05-07
4003 Disrupting USP39 deubiquitinase Function Impairs the Survival and Migration of Multiple Myeloma Cells through ZEB1 Degradation
Sirera, J.; Sarlak, S.; Teisseire, M.; Carminati, A.; Savy, C.; Nicolini, V.; Brest, P.; Bontoux, C.; Deckert, M.; Ohanna, M.; GIULIANO, S.; Dufies, M.; Pages, G.; Luciano, F.
10.1101/2024.04.23.590548 — cancer biology — Posted on 2024-05-07
4005 Multi-omics Reveals Immune Response and Metabolic Profiles during High-Altitude Mountaineering
Yin, J.; Lv, J.; Yang, S.; Wang, Y.; Huang, Z.; Wang, X.; Hou, G.; Zhou, W.; Liu, Y.; Wang, W.; Lin, X.; Huang, Y.; Zheng, Y.; Wei, C.; Yuan, Y.; Huang, Y.; Liu, C.; Tao, H.; Liu, H.; Liu, R.; Zhang, Y.; Zeng, G.; Gao, P.; Liu, L.; Cao, J.; Liu, C.; Jin, X.; Wang, J.
10.1101/2024.05.03.592361 — bioinformatics — Posted on 2024-05-07
4006 A cooperatively breeding mouse shows flexible use of its vocal repertoire according to social context
Perrier, L.; de Witasse-Thezy, A.; Pradeau, A.; Schradin, C.; Greenfield, M. D.; Mathevon, N.; Levrero, F.
10.1101/2024.05.07.592648 — animal behavior and cognition — Posted on 2024-05-07
4007 Fast and reliable ancestral reconstruction on ancient genotype data with non-negative Least square and Principal Component Analysis
de Gennaro, L.; Molinaro, L.; Raveane, A.; Santonastaso, F.; Saponetti, S. S.; Massi, M. C.; Pagani, L.; Metspalu, M.; Hellenthal, G.; Kivisild, T.; Ventura, M.; Montinaro, F.
10.1101/2024.05.06.592724 — genomics — Posted on 2024-05-07
4009 Comparison of Wild-Type and High-risk PNPLA3 variants in a Human Biomimetic Liver Microphysiology System for Metabolic Dysfunction-associated Steatotic Liver Disease Precision Therapy
Xia, M.; Varmazyad, M.; Palacin, I. P.; Gavlock, D. C.; Debiasio, R.; LaRocca, G.; Reese, C.; Florentino, R.; Faccioli, L. A. P.; Brown, J. A.; Vernetti, L. A.; Schurdak, M. E.; Stern, A. M.; Gough, A.; Behari, J.; Soto-Gutierrez, A.; Taylor, D. L.; Miedel, M.
10.1101/2024.04.22.590608 — cell biology — Posted on 2024-05-07
4012 StereoMM: A Graph Fusion Model for Integrating Spatial Transcriptomic Data and Pathological Images
Luo, B.; Teng, F.; Tang, G.; Chen, W.; Qu, C.; Liu, X.; Liu, X.; Liu, X.; Huang, H.; Feng, Y.; Zhang, X.; Jian, M.; Li, M.; Xi, F.; Li, G.; Liao, S.; Chen, A.; Xu, X.; Zhang, J.
10.1101/2024.05.04.592486 — bioinformatics — Posted on 2024-05-07
4013 Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals
Mi, X.; Chen, A. B.-Y.; Duarte, D.; Carey, E.; Taylor, C. R.; Braaker, P. N.; Bright, M.; Almeida, R. G.; Lim, J.-X.; Rutten, V. M.; Zheng, W.; Wang, M.; Reitman, M. E.; Wang, Y.; Poskanzer, K. E.; Lyons, D. A.; Nimmerjahn, A.; Ahrens, M. B.; Yu, G.
10.1101/2024.05.02.592259 — neuroscience — Posted on 2024-05-07
4014 Genetic variants associated with cell-type-specific intra-individual gene expression variability reveal new mechanisms of genome regulation
Powell, J. E.; Xue, A.; Yazar, S.; Alquicira, J.; Cuomo, A.; Senabouth, A.; Gordon, G.; Kathail, P.; Ye, J.; Hewitt, A.
10.1101/2024.05.05.592598 — genomics — Posted on 2024-05-07
4015 Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling
Giamundo, G.; Intartaglia, D.; Del Prete, E.; Polishchuk, E.; Andreone, F.; Ognibene, M.; Buonocore, S.; Salierno, F. G.; Monfregola, J.; Antonini, D.; Grumati, P.; Eva, A.; De Cegli, R.; Conte, I.
10.1101/2024.05.03.592332 — cell biology — Posted on 2024-05-07
4016 Live-cell single-molecule fluorescence microscopy for protruding organelles reveals regulatory mechanisms of MYO7A-driven cargo transport in stereocilia of inner ear hair cells
Miyoshi, T.; Vishwasrao, H. D.; Belyantseva, I. A.; Sajeevadathan, M.; Ishibashi, Y.; Adadey, S. M.; Harada, N.; Shroff, H.; Friedman, T. B.
10.1101/2024.05.04.590649 — cell biology — Posted on 2024-05-07
4017 Mitochondria-derived Vesicles mediate Mito-nuclear Trafficking of Cargo
Rajeev, T.; Shil, D.; Bhattacharjee, S.; Ramesh, L.; Samuel, V.; Nair, N. Y.; Marib, A.; Jayakumar, M.; Surendran, A.; Sundararaman, A.
10.1101/2024.05.04.592299 — cell biology — Posted on 2024-05-07
4019 Campylobacter infection of young children in Colombia and its impact on the gastrointestinal environment
Burcham, Z. M.; Tweedie, J.; Farfan-Garcia, A. E.; Nolan, V.; Donohoe, D.; Gomez-Duarte, O. G.; Johnson, J. G.
10.1101/2024.05.06.592725 — microbiology — Posted on 2024-05-07
4020 A continuous dynamic genome-scale model explains batch fermentations led by species of the Saccharomyces genus.
R. Moimenta, A.; Troitino-Jordedo, D.; Henriques, D.; Contreras-Ruiz, A.; Minebois, R.; Morard, M.; Barrio, E.; Querol, A.; Balsa-Canto, E.
10.1101/2024.05.03.592398 — systems biology — Posted on 2024-05-07
4021 A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta
Kimura, K.; Motoyama, E.; Kanki, S.; Asano, K.; Sheikh, M. A. A.; Clarin, M. T. R. D. C.; Raja, E.; Takeda, M.; Ishii, R.; Murata, K.; Deleeuw, V.; Sips, P.; Muino-Mosquera, L.; De Backer, J.; Mizuno, S.; Sakai, L. Y.; Nakamura, T.; Yanagisawa, H.
10.1101/2024.05.02.592287 — pathology — Posted on 2024-05-07
4022 Colorectal ALOX15 as a host factor determinant of EPA and DHA effects on colorectal carcinogenesis
Zuo, X.; Kiyasu, Y.; Liu, Y.; Deguchi, Y.; Liu, F.; Moussalli, M.; Tan, L.; Wei, B.; Wei, D.; Yang, P.; Shureiqi, I.
10.1101/2024.05.02.592224 — cancer biology — Posted on 2024-05-07
4023 Multi-omics Reveals Immune Response and Metabolic Profiles during High-Altitude Mountaineering
Yin, J.; Lv, J.; Yang, S.; Wang, Y.; Huang, Z.; Wang, X.; Hou, G.; Zhou, W.; Liu, Y.; Wang, W.; Lin, X.; Huang, Y.; Zheng, Y.; Wei, C.; Yuan, Y.; Huang, Y.; Liu, C.; Tao, H.; Liu, H.; Liu, R.; Zhang, Y.; Zeng, G.; Gao, P.; Liu, L.; Cao, J.; Liu, C.; Jin, X.; Wang, J.
10.1101/2024.05.03.592361 — bioinformatics — Posted on 2024-05-07
4025 Design and Technical Feasibility Testing of a Medical Robot for Flexible Catheter Navigation Inside the Lung Airways
Gruionu, L. G.; Lango, T.; Leira, H. O.; Hofstad, E. F.; Udristoiu, A. L.; Iacob, A. V.; Constantinescu, C.; Chihaia, C.; Gruionu, G.
10.1101/2024.05.01.592024 — bioengineering — Posted on 2024-05-07
4027 Disentangling cell-intrinsic and extrinsic factors underlying gene expression evolution
Starr, A. L.; Nishimura, T.; Igarashi, K. J.; Funamoto, C.; Nakauchi, H.; Fraser, H.
10.1101/2024.05.06.592777 — evolutionary biology — Posted on 2024-05-07
4031 Exploring the conformational ensembles of protein-protein complex with transformer-based generative model
Wang, J.; Wang, X.; Chu, Y.; Li, C.; Li, X.; Meng, X.; Fang, Y.; No, K. T.; Mao, J.; Zeng, X.
10.1101/2024.02.24.581708 — bioinformatics — Posted on 2024-05-07
4033 Sexually antagonistic co-evolution can explain female display signals and male sensory adaptations.
Wiberg, R. A. W.; Murray, R. L.; Herridge, E.; Parssinen, V.; Gwynne, D. T.; Bussiere, L. F.
10.1101/2022.03.14.484300 — evolutionary biology — Posted on 2024-05-07
4036 Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.
Estevam, G. O.; Linossi, E. M.; Macdonald, C. B.; Espinoza, C. A.; Michaud, J. M.; Coyote-Maestas, W.; Collisson, E. A.; Jura, N.; Fraser, J. S.
10.1101/2023.08.03.551866 — molecular biology — Posted on 2024-05-07
4037 Adaptive thermogenesis is mediated by GDF15 via the GFRAL neuronal axis in mice
Kim, J. E.; Ju, S.-H.; Lee, M.; Hong, H. J.; Yaseen, U.; Zhang, B.; Lee, S. E.; Kang, Y. E.; Kim, J. T.; Yi, H.-S.; Yi, Y.-S.; Jun, S.; Park, M.; Kim, J.; Auwerx, J.; Sohn, J.-W.; Lee, J. H.; Shong, M.
10.1101/2024.01.15.575796 — molecular biology — Posted on 2024-05-07
4040 Sleep and Activity Patterns in Autism Spectrum Disorder
Weissenkampen, J. D.; Ghorai, A.; Fasolino, M.; Gehringer, B. N.; Rajan, M.; Dow, H. C.; Sebro, R.; Rader, D. J.; Keenan, B. T.; Almasy, L.; Bucan, M.
10.1101/2024.05.02.592263 — neuroscience — Posted on 2024-05-07
4041 Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1
De-la-Torre, P.; Martinez-Garcia, C.; Gratias, P.; Mun, M.; Santana, P.; Akyuz, N.; Gonzalez, W.; Indzhykulian, A. A.; Ramirez, D.
10.1101/2024.03.05.583611 — neuroscience — Posted on 2024-05-07
4044 Flavonols improve thermotolerance in tomato pollen during germination and tube elongation by maintaining ROS homeostasis
Postiglione, A.; Delange, A.; Ali, M. F.; Wang, E. Y.; Houben, M. K.; Hahn, S. L.; Khoury, M.; Roark, C. M.; Davis, M.; Reid, R. W.; Pease, J. B.; Loraine, A. E.; Muday, G. K.
10.1101/2023.12.23.573189 — plant biology — Posted on 2024-05-07
4049 Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
Kliche, J.; Simonetti, L.; Krystkowiak, I.; Kuss, H.; Diallo, M.; Rask, E.; Nilsson, J.; Davey, N.; Ivarsson, Y.
10.1101/2023.09.18.558189 — biochemistry — Posted on 2024-05-07
4054 Engineered Oxalate decarboxylase boosts activity and stability for biological applications
Dindo, M.; Conter, C.; Uechi, G.-I.; Pampalone, G.; Ruta, L.; Pey, A. L.; Rossi, L.; Laurino, P.; Magnani, M.; Cellini, B.
10.1101/2024.05.06.592502 — biochemistry — Posted on 2024-05-06
4055 Bilirubin is a new ligand for nuclear receptor Liver Receptor Homolog-1.
Chapagain, P.; Haratipour, Z.; Malabanan, M. M.; Choi, W. J.; Blind, R.
10.1101/2024.05.05.592606 — biochemistry — Posted on 2024-05-06
4056 An efficient biochemical method for characterizing and classifying potentially amyloidogenic and therapeutic peptides
PRADEAU-PHELUT, L.; ALVES, S.; LE TAREAU, L.; LARRALDE, C.; BERNARD, E.; LAI KEE HIM, J.; LEPVRIER, E.; BRON, P.; DELAMARCHE, C.; Garnier, C.
10.1101/2024.05.06.592687 — biochemistry — Posted on 2024-05-06
4057 Homologous recombination promotes mitotic death to suppress the innate immune response
Szmyd, R.; Casolin, S.; French, L.; Gonzalez Manjon, A.; Dhawan, A.; Nelson, C. B.; Cavalli, L.; Page, S. G.; Hau, E.; Pickett, H. A.; Gee, H. E.; Cesare, A. J.
10.1101/2024.05.04.592546 — cell biology — Posted on 2024-05-06
4060 Chromatin protein complexes involved in gene repression in lamina-associated domains
Manzo, S.; Mazouzi, A.; Leemans, C.; van Schaik, T.; Neyazi, N.; van Ruiten, M. S.; Rowland, B. D.; Brummelkamp, T. R.; van Steensel, B.
10.1101/2024.05.05.592629 — molecular biology — Posted on 2024-05-06
4061 Monitoring of the invasive round goby in an estuarine seascape based on eDNA
Green, L.; Dahlgren, T. G.; Axberg, A.; Panova, M.; Obst, M.; Sundberg, P.
10.1101/2024.05.06.592655 — molecular biology — Posted on 2024-05-06
4064 Chromatin condensates tune nuclear mechano-sensing in Kabuki Syndrome by constraining cGAS activation
D'Annunzio, S.; Santomaso, L.; Michelatti, D.; Bernardis, C.; Vitali, G.; Lago, S.; Testi, C.; Pontecorvo, E.; Poli, A.; Pennachio, F.; Maiuri, P.; Sanchez, E.; Genevieve, D.; Petrolli, L.; Tarenzi, T.; Menichetti, R.; Potestio, R.; Ruocco, G.; Zippo, a.
10.1101/2024.05.06.592652 — molecular biology — Posted on 2024-05-06
4065 GPT-4 based AI agents - the new expert system for detection of antimicrobial resistance mechanisms?
Gieske, C. G.; Bressan, M.; Fiechter, F.; Hinic, V.; Mancini, S.; Nolte, O.; Egli, A.
10.1101/2024.05.06.592800 — microbiology — Posted on 2024-05-06
4066 Impact of the elderly lung mucosa on Mycobacterium tuberculosis metabolic adaptation during infection of alveolar epithelial cells
Olmo-Fontanez, A. M.; Allue-Guardia, A.; Garcia-Vilanova, A.; Glenn, J.; Wang, S.-H.; Merritt, R. E.; Schlesinger, L. S.; Turner, J.; Wang, Y.; Torrelles, J. B.
10.1101/2024.05.06.592753 — microbiology — Posted on 2024-05-06
4071 Full genome sequencing of dozens of new DNA viruses found in Spanish bat faeces
Buigues, J.; Vinals, A.; Martinez-Recio, R.; Monros, J. S.; Sanjuan, R.; Cuevas, J. M.
10.1101/2024.05.06.592742 — microbiology — Posted on 2024-05-06
4072 Bispecific antibodies with broad neutralization potency against SARS-CoV-2 variants of concern
Rubio, A. A.; Baharani, V. A.; Dadonaite, B.; Parada, M.; Abernathy, M. E.; Wang, Z.; Lee, Y. E.; Eso, M.; Phung, J.; Ramos, I.; Chen, T.; El Nesr, G.; Bloom, J. D.; Bieniasz, P. D.; Nussenzweig, M. C.; Barnes, C. O.
10.1101/2024.05.05.592584 — immunology — Posted on 2024-05-06
4075 Metabolic enzymes moonlight as selective autophagy receptors to protect plants against viral-induced cellular damage
Clavel, M.; Bianchi, A.; Kobylinska, R.; Groh, R.; Ma, J.; Papareddy, R. K.; Grujic, N.; Picchianti, L.; Stewart, E.; Schutzbier, M.; Stejskal, K.; de la Concepcion, J. C.; Hernandez, V. S. d. M.; Voichek, Y.; Clauw, P.; Gunis, J.; Durnberger, G.; Muelders, J. C.; Grimm, A.; Sedivy, A.; Erhardt, M.; Vyboishchikov, V.; Gao, P.; Lechner, E.; Vantard, E.; Jez, J.; Roitinger, E.; Genschik, P.; Kang, B.-H.; Dagdas, Y.
10.1101/2024.05.06.590709 — plant biology — Posted on 2024-05-06
4076 A general algorithm for consensus 3D cell segmentation from 2D segmented stacks
Zhou, F. Y.; Yapp, C.; Shang, Z.; Daetwyler, S.; Marin, Z.; Islam, M. T.; Nanes, B. A.; Jenkins, E.; Gihana, G. M.; Chang, B.-J.; Weems, A.; Dustin, M.; Morrison, S. J.; Fiolka, R. P.; Dean, K. M.; Jamieson, A.; Sorger, P. K.; Danuser, G.
10.1101/2024.05.03.592249 — bioinformatics — Posted on 2024-05-06
4077 RealtimeDecoder: A fast software module for online clusterless decoding
Chu, J. P.; Coulter, M. E.; Denovellis, E. L.; Nguyen, T. T.; Liu, D. F.; Deng, X.; Eden, U. T.; Kemere, C. T.; Frank, L. M.
10.1101/2024.05.03.592417 — neuroscience — Posted on 2024-05-06
4078 Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1
De-la-Torre, P.; Martinez-Garcia, C.; Gratias, P.; Mun, M.; Santana, P.; Akyuz, N.; Gonzalez, W.; Indzhykulian, A. A.; Ramirez, D.
10.1101/2024.03.05.583611 — neuroscience — Posted on 2024-05-06
4079 Nuclear Pyruvate Dehydrogenase Complex Regulates Histone Acetylation and Transcriptional Regulation in the Ethylene Response
Shao, Z.; Bian, L.; Ahmadi, S. K.; Daniel, T. J.; Belmonte, M. A.; Burns, J. G.; Kotla, P.; Bi, Y.; Shen, Z.; Xu, S.-L.; Wang, Z.-Y.; Briggs, S. P.; Qiao, H.
10.1101/2023.10.25.564010 — plant biology — Posted on 2024-05-06
4081 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging
Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.
10.1101/2023.10.30.564754 — bioengineering — Posted on 2024-05-06
4082 Directed evolution for cell separation in budding yeast
Galeota-Sprung, B.; Pritchard, E.; Huang, C.; Fernandez, A.; Sniegowski, P. D.
10.1101/2024.05.03.592462 — evolutionary biology — Posted on 2024-05-06
4083 The calcium pump PMCA4b promotes epithelial cell polarization and lumen formation
Toth, S.; Kaszas, D.; Sonyak, J.; Tokes, A.-M.; Padanyi, R.; Papp, B.; Nagy, R.; Vörös, K.; Csizmadia, T.; Tordai, A.; Enyedi, A.
10.1101/2024.01.20.576436 — cell biology — Posted on 2024-05-06
4084 Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions
Burns, G. W.; Fu, Z.; Vegter, E. L.; Madaj, Z. B.; Greaves, E.; Flores, I.; Fazleabas, A. T.
10.1101/2024.03.23.586434 — molecular biology — Posted on 2024-05-06
4085 Epigenetic memory is governed by an effector recruitment specificity toggle in Heterochromatin Protein 1
Ames, A.; Seman, M.; Larkin, A.; Raiymbek, G.; Chen, Z.; Levashkevich, A.; Kim, B.; Biteen, J. S.; Ragunathan, K.
10.1101/2023.11.28.569027 — molecular biology — Posted on 2024-05-06
4086 Artificially inserted G-quadruplex DNA secondary structures induce long-distance chromatin activation
Roy, S. S.; Bagri, S.; Vinayagamurthy, S.; Sengupta, A.; Then, C. R.; Kumar, R.; Sridharan, S.; Chowdhury, S.
10.1101/2023.11.27.568900 — molecular biology — Posted on 2024-05-06
4087 Alpha phase-coding supports feature binding during working memory maintenance
Pagnotta, M. F.; Santo-Angles, A.; Temudo, A.; Barbosa, J.; Compte, A.; D'Esposito, M.; Sreenivasan, K. K.
10.1101/2024.01.21.576561 — neuroscience — Posted on 2024-05-06
4088 Metabolite accumulation from oral NMN supplementation drives aging-specific kidney inflammation
Saleh, T. A.; Whitson, J. A.; Keiser, P.; Prasad, P.; Jenkins, B. C.; Sodeinde, T.; Mann, C.; Rabinovitch, P. S.; McReynolds, M. R.; Sweetwyne, M. T.
10.1101/2024.04.09.588624 — physiology — Posted on 2024-05-06
4089 Combination fedratinib and venetoclax has activity against human B-ALL with high FLT3 expression
Rinella, S. P.; Bell, H. C.; Hess, N. J.; Hoang, N.-M.; Nguyen, T. T.; Turicek, D. P.; Shi, L.; Rui, L.; LaBelle, J. L.; Capitini, C. M.
10.1101/2023.06.07.544058 — cancer biology — Posted on 2024-05-06
4093 Revealing the evolutionary history and contemporary population structure of Pacific salmon in the Fraser River through genome resequencing
Christensen, K. A.; Flores, A.-M.; Sakhrani, D.; Biagi, C. A.; Devlin, R. H.; Sutherland, B. J. G.; Withler, R. E.; Rondeau, E. B.; Koop, B. F.
10.1101/2024.04.29.591761 — evolutionary biology — Posted on 2024-05-06
4095 CD74+ fibroblasts proliferate upon mechanical stretching to promote angiogenesis in keloid
Zhang, J.; Li, S.; Kuang, C.; Shen, Y.; Yu, H.; Chen, F.; Tang, R.; Mao, S.; Lv, L.; Qi, M.; Zhang, J.; Yuan, K.
10.1101/2024.05.05.592627 — cell biology — Posted on 2024-05-06
4098 Global biogeography of N2-fixing microbes: nifH amplicon database and analytics workflow
Morando, M.; Magasin, J.; Cheung, S.; Mills, M. M.; Zehr, J. P.; Turk-Kubo, K. A.
10.1101/2024.05.04.592440 — bioinformatics — Posted on 2024-05-06
4099 FKBP11 targeted plasma cells promote abdominal aortic aneurysm progression through an m6A-dependent mechanism
He, Y.; Xing, J.; Wang, S.; Jiang, H.; Lun, Y.; Han, Y.; Erhart, P.; Boeckler, D.; Zhang, J.
10.1101/2024.05.05.592616 — cell biology — Posted on 2024-05-06
4102 RealtimeDecoder: A fast software module for online clusterless decoding
Chu, J. P.; Coulter, M. E.; Denovellis, E. L.; Nguyen, T. T.; Liu, D. F.; Deng, X.; Eden, U. T.; Kemere, C. T.; Frank, L. M.
10.1101/2024.05.03.592417 — neuroscience — Posted on 2024-05-06
4106 A general algorithm for consensus 3D cell segmentation from 2D segmented stacks
Zhou, F. Y.; Yapp, C.; Shang, Z.; Daetwyler, S.; Marin, Z.; Islam, M. T.; Nanes, B. A.; Jenkins, E.; Gihana, G. M.; Chang, B.-J.; Weems, A.; Dustin, M.; Morrison, S. J.; Fiolka, R. P.; Dean, K. M.; Jamieson, A.; Sorger, P. K.; Danuser, G. K.
10.1101/2024.05.03.592249 — bioinformatics — Posted on 2024-05-06
4111 Expert Panel Curation of 31 Genes in Relation to Limb Girdle Muscular Dystrophy
Mohan, S.; McNulty, S.; Thaxton, C.; Elnagheeb, M.; Owens, E.; Flowers, M.; Nunnery, T.; Self, A.; Palus, B.; Gorokhova, S.; Kennedy, A.; Niu, Z.; Johari, M.; Baneye Maiga, A.; Macalalad, K.; Clause, A. R.; Beckmann, J. S.; Bronicki, L.; Cooper, S. T.; Ganesh, V. S.; Kang, P. B.; Kesari, A.; Lek, M.; Levy, J.; Rufibach, L.; Savarese, M.; Spencer, M. J.; Straub, V.; Tasca, G.; Weihl, C. C.
10.1101/2024.05.03.592369 — genetics — Posted on 2024-05-06
4112 Directed evolution for cell separation in budding yeast
Galeota-Sprung, B.; Sniegowski, P. D.; Pritchard, E.; Huang, C.; Fernandez, A.
10.1101/2024.05.03.592462 — evolutionary biology — Posted on 2024-05-06
4113 DNA replication errors are a major source of adaptive gene amplification
Chuong, J.; Ben Nun, N.; Suresh, I.; Matthews, J.; De, T.; Avecilla, G.; Abdul-Rahman, F.; Brandt, N.; Ram, Y.; Gresham, D.
10.1101/2024.05.03.589936 — evolutionary biology — Posted on 2024-05-06
4114 Insect abundance and richness response to ecological reclamation on well pads 5-12 years into succession in a semi-arid natural gas field
Curran, M. F.; Allison, J.; Robinson, T. J.; Robertson, B. L.; Knudson, A. H.; Bott, B. M. M.; Bower, S.; Saleh, B. M.
10.1101/2024.05.03.592291 — ecology — Posted on 2024-05-06
4115 Seabird and sea duck mortalities were lower during the second breeding season in eastern Canada following the introduction of Highly Pathogenic Avian Influenza A H5Nx viruses
Cormier, T.; Barychka, T.; Beaumont, M.; Burt, T. V.; English, M. D.; Giacinti, J. A.; Giroux, J.-F.; Guillemette, M.; Hargan, K. E. A.; Jones, M.; Lair, S.; Lang, A. S.; Lepage, C.; Montevecchi, W. A.; Rahman, I.; Rail, J.-F.; Robertson, G. J.; Ronconi, R. A.; Seyer, Y.; Taylor, L. U.; Ward, C. R. E.; Wight, J.; Wilhelm, S. I.; Avery-Gomm, S.
10.1101/2024.05.03.591923 — ecology — Posted on 2024-05-06
4116 Generation of spermatogonia from pluripotent stem cells in humans and non-human primates
Whelan, E. C.; Hwang, Y. S.; Seita, Y.; Yokomizo, R.; Leu, N. A.; Cheng, K.; Sasaki, K.
10.1101/2024.05.03.592203 — developmental biology — Posted on 2024-05-06
4118 Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host
Gonzalez-Aponte, M. F.; Damato, A. R.; Simon, T.; Aripova, N.; Darby, F.; Rubin, J. B.; Herzog, E. D.
10.1101/2024.05.03.592418 — neuroscience — Posted on 2024-05-06
4120 Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas
Kazansky, Y.; Mueller, H. S.; Cameron, D.; Demarest, P.; Zaffaroni, N.; Arrighetti, N.; Zuco, V.; Mundi, P. S.; Kuwahara, Y.; Somwar, R.; Qu, R.; Califano, A.; De Stanchina, E.; Dela Cruz, F. S.; Kung, A. L.; Gounder, M.; Kentsis, A.
10.1101/2024.05.03.592420 — cancer biology — Posted on 2024-05-06
4122 Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions
Jin, X.; Rosenbohm, J.; Ostadi Moghaddam, A.; Kim, E.; Seiffert-Sinha, K.; Leiker, M.; Zhai, H.; Baddam, S. R.; Minnick, G.; Huo, Y.; Tajvidi Safa, B.; Wahl, J. K.; Meng, F.; Huang, C.; Lim, J. Y.; Conway, D. E.; Sinha, A. A.; Yang, R.
10.1101/2024.05.03.592394 — biophysics — Posted on 2024-05-06
4123 GUIDE deconstructs genetic architectures using association studies
Lazarev, D.; Chau, G.; Bloemendal, A.; Churchhouse, C.; Neale, B.
10.1101/2024.05.03.592285 — genetics — Posted on 2024-05-06
4125 The tricellular junction protein ILDR2 in glomerulopathies: insights and implications
Siegerist, F.; Kliewe, F.; Hammer, E.; Schakau, P.; Soh, J. E. C.; Weber, C.; Puelles, V.; Lindenmeyer, M.; Reichelt-Wurm, S.; Drenic, V.; Chatziantoniou, C.; Chadjichristos, C.; Zhang, Y.; Nauck, M.; Völker, U.; Endlich, N.
10.1101/2024.05.03.592456 — cell biology — Posted on 2024-05-06
4126 Regional patterns of human cortex development colocalize with underlying neurobiology
Lotter, L. D.; Saberi, A.; Hansen, J. Y.; Misic, B.; Paquola, C.; Barker, G. J.; Bokde, A. L. W.; Desrivieres, S.; Flor, H.; Grigis, A.; Garavan, H.; Gowland, P.; Heinz, A.; Bruehl, R.; Martinot, J.-L.; Paillere, M.-L.; Artiges, E.; Papadopoulos Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Froehner, J. H.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; IMAGEN Consortium, ; Nees, F.; Banaschewski, T.; Eickhoff, S. B.; Dukart, J.
10.1101/2023.05.05.539537 — neuroscience — Posted on 2024-05-06
4128 Pneumonia induced rise in glucagon promotes endothelial damage and vascular thrombogenicity
Ramezani Rad, P.; Nageswaran, V.; Peters, L.; Reinshagen, L.; Roessler, J.; Simmons, S.; Asmus, E.; Wittig, C.; Brack, M. C.; Nouailles, G.; Van der Vorst, E.; Maas, S. L.; Sonnenschein, K.; Verhaar, B. J. H.; Szulcek, R.; Witzenrath, M.; Landmesser, U.; Kuebler, W. M.; Haghikia, A.
10.1101/2024.05.03.592488 — physiology — Posted on 2024-05-06
4129 Identification of Fasnall as a therapeutically effective Complex I inhibitor
Mukha, D.; Dessain, J.; O'Connor, S.; Pniewski, K.; Bertolazzi, F.; Patel, J.; Mullins, M. C.; Schug, Z. T.
10.1101/2024.05.03.592013 — cancer biology — Posted on 2024-05-06
4133 Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing
Reedy, J. L.; Jensen, K. N.; Crossen, A. J.; Basham, K. J.; Ward, R. A.; Reardon, C. M.; Harding, H. B.; Hepworth, O. W.; Simaku, P.; Kwaku, G. N.; Tone, K.; Willment, J. A.; Reid, D. M.; Stappers, M. H.; Brown, G. D.; Rajagopal, J.; Vyas, J. M.
10.1101/2023.03.28.534632 — immunology — Posted on 2024-05-06
4134 Novel clock neuron subtypes regulate temporal aspects of sleep
Ma, D.; Le, J. Q.; Dai, X.; Diaz, M.; Abruzzi, K.; Rosbash, M.
10.1101/2024.05.03.592478 — neuroscience — Posted on 2024-05-06
4136 Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation
Ramnauth, A. D.; Tippani, M.; Divecha, H. R.; Papariello, A. R.; Miller, R. A.; Nelson, E. D.; Pattie, E. A.; Kleinman, J. E.; Maynard, K. R.; Collado-Torres, L.; Hyde, T. M.; Martinowich, K.; Hicks, S. C.; Page, S. C.
10.1101/2023.11.20.567883 — neuroscience — Posted on 2024-05-06
4140 Estropausal gut microbiota transplant improves ovarian function in adult mice
Kim, M.; Wang, J.; Lu, R. J.; Kim, Y.; Liu, M.; Fu, X.; Booth, S. L.; Benayoun, B. A.
10.1101/2024.05.03.592475 — physiology — Posted on 2024-05-06
4143 Discovering and Validating Neoantigens by Mass Spectrometry-based Immunopeptidomics and Deep Learning
Tran, N. H.; Peng, C.; Lei, Q.; Xin, L.; Lang, J.; Zhang, Q.; Li, W.; Miao, H.; Wu, P.; Qiao, R.; Qin, H.; Bu, D.; Zhang, H.; Yu, C.; Liu, X.; Zhang, Y.; Shan, B.; Li, M.
10.1101/2022.07.05.497667 — bioinformatics — Posted on 2024-05-06
4145 Mycelium as a scaffold for biomineralized engineered living materials
Viles, E.; Heyneman, E.; Lin, S.; Montague, V.; Darabi, A.; Cox, L.; Phillips, A.; Gerlach, R.; Espinosa-Ortiz, E.; Heveran, C. M.
10.1101/2024.05.03.592484 — bioengineering — Posted on 2024-05-06
4147 Functional dissection of complex and molecular trait variants at single nucleotide resolution
Siraj, L.; Castro, R. I.; Dewey, H.; Kales, S.; Nguyen, T. T. L.; Kanai, M.; Berenzy, D.; Mouri, K.; Wang, Q.; McCaw, Z. R.; Gosai, S. J.; Aguet, F.; Cui, R.; Vockley, C. M.; Lareau, C. A.; Okada, Y.; Gusev, A.; Jones, T. R.; Lander, E. S.; Sabeti, P. C.; Finucane, H. K.; Reilly, S. K.; Ulirsch, J. C.; Tewhey, R.
10.1101/2024.05.05.592437 — genetics — Posted on 2024-05-06
4149 Dietary bacteria control C. elegans fat content through pathways converging at phosphatidylcholine
Han, H.-F.; Nien, S.-F.; Jiang, H.-S.; Wu, J.-C.; Chiang, C.-Y.; Li, M.-T.; Huang, L.-J.; Chiang, S.; Lin, L.-C.; Chuang, Y.-T.; Lin, Y.-H.; Wang, C.-W.; Wu, Y.-C.
10.1101/2024.02.24.581900 — cell biology — Posted on 2024-05-06
4151 Heparan sulfate dependent phase separation of CCL5 and its chemotactic activity
Yu, X.; Duan, G.; Pei, P.; Chen, L.; Gu, R.; Hu, W.; Zhang, H.; Wang, Y.-D.; Gong, L.; Liu, L.; Chu, T.-T.; Li, J.-P.; Luo, S.-Z.
10.1101/2023.11.15.567182 — cell biology — Posted on 2024-05-06
4152 Assessment of salivary microRNA by RT-qPCR: Challenges in data interpretation for clinical diagnosis
Van Der Hofstadt, M.; Cardinal, A.; Lepeltier, M.; Boulestreau, J.; Ouedraogo, A.; Kahli, M.; Champigneux, P.; Molina, L.; Molina, F.; Van, T. N. N.
10.1101/2024.02.06.579150 — molecular biology — Posted on 2024-05-06
4153 A Deep Learning-Based Segmentation of Cells and Analysis (DL-SCAN)
Bhattarai, A.; Meyer, J.; Petersilie, L.; Shah, S. I.; Rose, C. R.; Ullah, G.
10.1101/2024.05.03.592244 — neuroscience — Posted on 2024-05-06
4154 Prion diseases disrupt the glutamate/glutamine metabolism in skeletal muscle
Caredio, D.; Koderman, M.; Frontzek, K.; Sorce, S.; Nuvolone, M.; Bremer, J.; Schwarz, P.; Sellitto, S.; Streichenberger, N.; Scheckel, C.; Aguzzi, A.
10.1101/2023.10.31.564879 — neuroscience — Posted on 2024-05-06
4157 The whole blood microbiome of Indonesians reveals translocated and pathogenic microbiota
Bobowik, K. S.; Fachrul, M.; Darusalam, C.; Kusuma, P.; Sudoyo, H.; Febinia, C. A.; Malik, S.; Wells, C.; Gallego Romero, I.
10.1101/2022.04.24.489025 — genomics — Posted on 2024-05-06
4159 Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.
Estevam, G. O.; Linossi, E. M.; Macdonald, C. B.; Espinoza, C. A.; Michaud, J. M.; Coyote-Maestas, W.; Collisson, E. A.; Jura, N.; Fraser, J. S.
10.1101/2023.08.03.551866 — molecular biology — Posted on 2024-05-06
4166 ESCRT disruption provides evidence against signaling functions for synaptic exosomes
Dresselhaus, E. C.; Harris, K. P.; Blanchette, C. R. R.; Koles, K.; Del Signore, S. J.; Pescosolido, M. F.; Ermanoska, B.; Rozencwaig, M.; Soslowsky, R. C.; Parisi, M. J.; Stewart, B. A.; Mosca, T. J.; Rodal, A. A.
10.1101/2023.04.22.537920 — cell biology — Posted on 2024-05-05
4168 A deep-learning strategy to identify cell types across species from high-density extracellular recordings
Beau, M.; Herzfeld, D. J.; Naveros, F.; Hemelt, M. E.; D'Agostino, F.; Oostland, M.; Sanchez-Lopez, A.; Chung, Y. Y.; Maibach, M.; Kyranakis, S.; Stabb, H. N.; Martinez Lopera, M. G.; Lajko, A.; Zedler, M.; Ohmae, S.; Hall, N. J.; Clark, B. A.; Cohen, D.; Lisberger, S. G.; Kostadinov, D.; Hull, C.; Häusser, M.; Medina, J. F.
10.1101/2024.01.30.577845 — neuroscience — Posted on 2024-05-06
4172 Multilevel clinical fingerprinting: uncovering longitudinal changes in the functional connectome of the brain along the migraine cycle
Esteves, I.; Fouto, A. R.; Ruiz-Tagle, A.; Caetano, G.; Nunes, R. G.; da Silva, N. A.; Vilela, P.; Gil-Gouveia, R.; Pavao Martins, I.; Caballero-Gaudes, C.; Figueiredo, P.
10.1101/2024.05.02.592281 — bioengineering — Posted on 2024-05-05
4174 Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treat low-burden metastases
Huang, S.-W.; Lai, Y.-G.; Liao, H.-T.; Chang, C.-L.; Ma, R.-Y.; Chen, Y.-H.; Liou, Y.-H.; Wu, Z.-Q.; Wu, Y.-C.; Liu, K.-J.; Huang, Y.-T.; Yang, J.-L.; Dai, M.-S.; Liao, N.-S.
10.1101/2024.05.03.592329 — immunology — Posted on 2024-05-05
4177 Improving Predictability, Test-Retest Reliability and Generalisability of Brain-Wide Associations for Cognitive Abilities via Multimodal Stacking
Tetereva, A.; Knodt, A.; Melzer, T.; van der Vliet, W.; Gibson, B.; Hariri, A.; Whitman, E. T.; Li, J.; Deng, J.; Ireland, D.; Ramrakha, S.; Pat, N.
10.1101/2024.05.03.589404 — neuroscience — Posted on 2024-05-05
4178 Protection of savings by reducing the salience of opposing errors
Javidialsaadi, M.; Albert, S. T.; Moufarrej S Al Mutairi, B.; Wang, J.
10.1101/2024.05.03.592370 — neuroscience — Posted on 2024-05-05
4179 Cortical circuit principles predict patterns of trauma induced tauopathy in humans
Barbas, H.; Garcia-Cabezas, M. A.; John, Y. J.; Bautista, J.; McKee, A. C.; Zikopoulos, B.
10.1101/2024.05.02.592271 — neuroscience — Posted on 2024-05-05
4180 Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals
Mi, X.; Chen, A. B.-Y.; Duarte, D.; Carey, E.; Taylor, C. R.; Braaker, P. N.; Bright, M.; Almeida, R. G.; Lim, J.-X.; Rutten, V. M.; Zheng, W.; Wang, M.; Reitman, M. E.; Wang, Y.; Poskanzer, K. E.; Lyons, D. A.; Nimmerjahn, A.; Ahrens, M. B.; Yu, G.
10.1101/2024.05.02.592259 — neuroscience — Posted on 2024-05-05
4183 Human Organoid Tumor Transplantation Identifies Functional Glioblastoma - Microenvironmental Communication Mediated by PTPRZ1
Ge, W.; Kan, R. L.; Yilgor, C.; Fazzari, E.; Nano, P. R.; Azizad, D. J.; Li, M.; Ito, J. Y.; Tse, C.; Tum, H. A.; Scholes, J.; Patel, K. S.; Nathanson, D. A.; Bhaduri, A.
10.1101/2024.05.02.592055 — cancer biology — Posted on 2024-05-05
4189 Tumor-selective treatment of metastatic pancreatic cancer with an engineered, probiotic living drug
Decker-Farrell, A. R.; Sastra, S. A.; Harimoto, T.; Hasselluhn, M. C.; Palermo, C. F.; Ballister, E. R.; Badgley, M. A.; Danino, T.; Olive, K. P.
10.1101/2024.05.02.592216 — cancer biology — Posted on 2024-05-05
4191 Host-derived Interleukin 1α induces an immunosuppressive tumor microenvironment via regulating monocyte-to-macrophage differentiation
Keerthi Raja, M. R.; Gupta, G.; Atkinson, G.; Kathrein, K.; Armstrong, A.; Gower, M.; Roninson, I.; Broude, E.; Chen, M.; Ji, H.; Lim, C.; Wang, H.; Fan, D.; Xu, P.; Li, J.; Zhou, G.; Chen, H.
10.1101/2024.05.03.592354 — cancer biology — Posted on 2024-05-05
4196 Sampling Conformational Ensembles of Highly Dynamic Proteins via Generative Deep Learning
Chang, C.-e. A.; Ruzmetov, T.; Hung, T. I.; Jonnalagedda, S. P.; Chen, S.-h.; Fasihianifard, P.; Guo, Z.; Bhanu, B.
10.1101/2024.05.05.592587 — biophysics — Posted on 2024-05-05
4198 Mitochondrial Oxidative Phosphorylation Capacity in Skeletal Muscle Measured by Ultrafast Z-Spectroscopy (UFZ) MRI at 3T
Ju, L.; Schar, M.; Wang, K.; Li, A. M.; Wu, Y.; Samuel, T. J.; Ganji, S.; van Zijl, P. C. M.; Yadav, N. N.; Weiss, R. G.; Xu, J.
10.1101/2024.05.05.592570 — biophysics — Posted on 2024-05-05
4201 AgeML: Age modelling with Machine Learning
Garcia Condado, J.; Tellaetxe, I.; Cortes, J.; Erramuzpe, A.
10.1101/2024.05.02.592130 — bioinformatics — Posted on 2024-05-05
4203 A novel induced pluripotent stem cell model of schwann cell differentiation reveals NF2-related gene regulatory networks of the extracellular matrix
Lazaro, O.; Li, S.; Carter, W.; Awosika, O.; Robertson, S.; Hickey, B. E.; Angus, S. P.; House, A.; Clapp, D. W.; Qadir, A. S.; Johnson, T. S.; Rhodes, S. D.
10.1101/2024.05.02.591952 — bioinformatics — Posted on 2024-05-05
4204 LBFextract: unveiling transcription factor dynamics from liquid biopsy data
Lazzeri, I.; Spiegl, B.; Hasenleithner, S. O.; Speicher, M. R.; Kircher, M.
10.1101/2024.05.03.592314 — bioinformatics — Posted on 2024-05-05
4206 A molecular representation to identify isofunctional molecules
Pinel, P.; Guichaoua, G.; Devaux, N.; Gaston-Mathe, Y.; Hoffmann, B.; Stoven, V.
10.1101/2024.05.03.592355 — bioinformatics — Posted on 2024-05-05
4209 Conditional language models enable the efficient design of proficient enzymes
Mumsamy, G.; Illanes-Vicioso, R.; Fruncillo, S.; Nakou, I. T.; Lindner, S.; Ayres, G.; Sheehan, L. S.; Moss, S.; Eckhard, U.; Lorenz, P.; Ferruz, N.
10.1101/2024.05.03.592223 — bioinformatics — Posted on 2024-05-05
4210 Enhancing Biosecurity with Watermarked Protein Design
Chen, Y.; Hu, Z.; Wu, Y.; Chen, R.; Jin, Y.; Chen, W.; Huang, H.
10.1101/2024.05.02.591928 — bioinformatics — Posted on 2024-05-05
4213 Locityper: targeted genotyping of complex polymorphic genes
Prodanov, T.; Plender, E. G.; Seebohm, G.; Meuth, S. G.; Eichler, E. E.; Marschall, T.
10.1101/2024.05.03.592358 — bioinformatics — Posted on 2024-05-05
4217 IFN-γ activates an immune-like regulatory network in the cardiac vascular endothelium
Arthur, T. D.; Joshua, I. N.; Nguyen, J. P.; D'Antonio-Chronowska, A.; iPSCORE Consortium, ; Frazer, K. A.; D'Antonio, M.
10.1101/2024.05.03.592380 — bioinformatics — Posted on 2024-05-05
4218 Recombinant manufacturing of multispecies biolubricants
Colville, M. J.; Huang, L.-T.; Schmidt, S.; Chen, K. J.; Vishwanath, K.; Su, J.; Williams, R.; Bonassar, L.; Reesink, H. L.; Paszek, M. J.
10.1101/2024.05.05.592580 — bioengineering — Posted on 2024-05-05
4223 hESCs-derived organoids achieve liver zonation by LSEC modulation
Zhang, Y.; Huang, C.; Sun, L.; Zhou, L.; Liang, K.; Niu, Y.; Wu, B.; Du, Y.
10.1101/2024.05.05.592562 — bioengineering — Posted on 2024-05-05
4224 kinact/KI Value Determination for Penicillin-Binding Proteins in Live Cells
Shirley, J. D.; Nauta, K. M.; Gillingham, J. R.; Diwakar, S.; Carlson, E. E.
10.1101/2024.05.05.592586 — biochemistry — Posted on 2024-05-05
4226 Multi-omics delineate growth factor network underlying exercise effects in an Alzheimer's mouse model
Li, X.; Liu, C.; Li, W.; Dai, Y.; Gu, C.; Zhou, W.; Ciliberto, V. C.; Liang, J.; Kumar. S, U.; Guan, D.; Hu, Z.; Zheng, H.; Chen, H.; Liu, Z.; Wan, Y.-W.; Sun, Z.
10.1101/2024.05.02.592289 — animal behavior and cognition — Posted on 2024-05-05
4227 Deep Imputation for Skeleton Data (DISK) for Behavioral Science
Rose, F.; Michaluk, M.; Blindauer, T.; Ignatowska-Jankowska, B. M.; O'Shaughnessy, L.; Stephens, G. J.; Pereira, T. D.; Uusisaari, M. Y.; Bozek, K.
10.1101/2024.05.03.592173 — animal behavior and cognition — Posted on 2024-05-05
4229 Tri-omic mapping revealed concerted dynamics of 3D epigenome and transcriptome in brain cells
Chai, H.; Huang, X.; Xiong, G.; Huang, J.; Pels, K. K.; Meng, L.; Han, J.; Tang, D.; Pan, G.; Deng, L.; Xiao, Q.; Wang, X.; Zhang, M.; Banecki, K.; Plewczynski, D.; Wei, C.-L.; Ruan, Y.
10.1101/2024.05.03.592322 — genomics — Posted on 2024-05-05
4230 Reproducible single cell annotation of programs underlying T-cell subsets, activation states, and functions
Kotliar, D.; Curtis, M.; Agnew, R.; Weinand, K.; Nathan, A.; Baglaenko, Y.; Zhao, Y.; Sabeti, P. C.; Rao, D. A.; Raychaudhuri, S.
10.1101/2024.05.03.592310 — genomics — Posted on 2024-05-05
4231 The assembly and annotation of two teinturier grapevine varieties, Dakapo and Rubired
Ritter, E. J.; Cochetel, N.; Minio, A.; Cousins, P.; Cantu, D. J.; Niederhuth, C.
10.1101/2024.05.03.592245 — genomics — Posted on 2024-05-05
4232 Genomes of two indigenous clams Anomalocardia flexuosa (Linnaeus, 1767) and Meretrix petechialis (Lamarck, 1818)
law, S. T. S.; Nong, W.; Au, M. F. F.; Cheung, L. H. T.; Shum, C. W. Y.; Lee, S. Y.; Cheung, S. G.; Hui, J. H. L.
10.1101/2024.05.03.592324 — genomics — Posted on 2024-05-05
4234 Multi-trait modeling and machine learning discover new markers associated with stem traits in alfalfa
Xu, Z.; Medina, C. A.; Heuschele, D. J.; Zhao, D.; Lin, M.; Beil, C. T.; Sheehan, M. J.
10.1101/2024.05.03.592319 — genomics — Posted on 2024-05-05
4236 Molecular identification of whole squids and calamari at fairs and markets in regions of Latin America
Paiva, B. L.; Rodrigues, A. E. S.; Almeida, I. O. F.; Haimovici, M.; Markaida, U.; Charvet, P.; Faria, V. V.; Batista, B. B.; Gomes, A. R. T.; Rodrigues-Filho, L. F.; Ready, J. S.; Sales, J. B. L.
10.1101/2024.05.03.590921 — genetics — Posted on 2024-05-05
4237 Molecular correlates of swarming behaviour in Aedes aegypti males.
Feuda, R.; Rosato, E.; Devilliers, J.; Bruno, R. V.; Marshall, H.; Araripe, L. O.; Warren, B.; Kyriacou, C. P.
10.1101/2024.05.03.591282 — genetics — Posted on 2024-05-05
4238 Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk
Kramer, N. E.; Coryell, P.; D'Costa, S.; Thulson, E.; Byun, S.; Kim, H.; Parkus, S. M.; Bond, M. L.; Shine, J.; Chubinskaya, S.; Love, M. I.; Mohlke, K. L.; Diekman, B. O.; Loeser, R. F.; Phanstiel, D. H.
10.1101/2024.05.05.592567 — genetics — Posted on 2024-05-05
4241 Cold adaptation in Upper Paleolithic hunter-gatherers of eastern Eurasia
Watanabe, Y.; Wakiyama, Y.; Waku, D.; Valverde, G.; Tanino, A.; Nakamura, Y.; Suzuki, T.; Koganebuchi, K.; Gakuhari, T.; Katsumura, T.; Ogawa, M.; Toyoda, A.; Mizushima, S.; Nagaoka, T.; Hirata, K.; Yoneda, M.; Nishimura, T.; Izuho, M.; Yamada, Y.; Masuyama, T.; Takahashi, R.; Ohashi, J.; NCBN Controls WGS Consortium, ; Oota, H.
10.1101/2024.05.03.591810 — evolutionary biology — Posted on 2024-05-05
4246 The evolutionary history and functional specialization of microRNA genes in Arabidopsis halleri and A. lyrata
Flavia, P.; Azevedo Favory, J.; Lacoste, E.; Beaumont, C.; Louis, F.; Blassiau, C.; Cruaud, C.; Labadie, K.; Gallina, S.; Genete, M.; Kumar, V.; Kramer, U.; Adriano Batista, R.; Patiou, C.; Debacker, L.; Ponitzki, C.; Houze, E.; Durand, E.; Aury, J.-M.; Castric, V.; Legrand, S.
10.1101/2024.05.03.592357 — evolutionary biology — Posted on 2024-05-05
4247 The global fish and invertebrate abundance value of mangroves
zu Ermgassen, P.; Worthington, T. A.; Gair, J. R.; Garnett, E. E.; Mukherjee, N.; Longley-Wood, K.; Nagelkerken, I.; Abrantes, K.; Aburto-Oropeza, O.; Acosta, A.; Araujo, A. R. d. R.; Baker, R.; Barnett, A.; Beitl, C. M.; Benzeev, R.; Brookes, J.; Castellanos-Galindo, G. A.; Ching Chong, V.; Connolly, R. M.; Cunha-Lignon, M.; Dahdouh-Guebas, F.; Diele, K.; Dwyer, P. G.; Friess, D. A.; Grove, T.; Hoq, M. E.; Huijbers, C.; Hutchinson, N.; Johnson, A. F.; Johnson, R.; Knight, J.; Krumme, U.; Kuguru, B.; Lee, S. Y.; Lobo, A. S.; Lugendo, B. R.; Meynecke, J.-O.; Nzaka Munga, C.; Olds, A. D.; Parret
10.1101/2024.05.02.591889 — ecology — Posted on 2024-05-05
4258 Hijacked Immune Cells Traverse Microenvironmental Barriers by Positioning and Pushing their Intracellular Parasite Cargo
Ruiz-Fernandez, M. J. A.; Jang, J.; Mortazavi, A.; Wang, B.; Kuznetcov, A.; Merrin, J.; Meissner, M.; Periz, J.; Sabass, B.; Renkawitz, J.
10.1101/2024.05.03.592378 — cell biology — Posted on 2024-05-05
4259 mTOR dysregulation induces IL6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis
Babaei-Jadidi, R.; Clements, D.; Wu, Y.; Chen, K.; Miller, S.; Plate, M.; Lim, K.; Chambers, R.; Rawlins, E. L.; Xu, Y.; Johnson, S. R.
10.1101/2024.05.03.592025 — cell biology — Posted on 2024-05-05
4260 Protein S-glutathionylation confers cell resistance to ferroptosis
Ju, Y.; Zhang, Y.; Qiao, Y.; Tian, X.; Zheng, Y.; Yang, T.; Niu, B.; Li, X.; Yu, L.; Liu, Z.; Wu, Y.; Zhi, Y.; Dong, Y.; Xu, Q.; Wang, X.; Wang, X.; Mao, Y.; Li, X.
10.1101/2024.05.03.592374 — cell biology — Posted on 2024-05-05
4263 Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription
Liu, H.; Teng, Z.; Yang, L.; Zhang, Q.; Chen, Y.; Wang, X.; Zheng, Y.; Tian, A.; Tian, D.; Lin, Z.; Deng, W.-M.
10.1101/2024.05.03.592391 — cell biology — Posted on 2024-05-05
4265 NK Cell Exhaustion in Wilson's Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis
Jin, Y.; Xing, J.; Dai, C.; Jin, L.; Zhang, W.; Tao, Q.; Hou, M.; Li, Z.; Yang, W.; Feng, Q.; Wang, H.; Yu, Q.
10.1101/2024.05.02.592210 — immunology — Posted on 2024-05-05
4266 Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer
Ghisoni, E.; Benedetti, F.; Minasyan, A.; Cunnea, P.; Grimm, A. J.; Fahr, N.; Desbuisson, M.; Capt, C.; Rayroux, N.; Gulhan, D. C.; Dagher, J.; Barras, D.; Morotti, M.; Marin Jimenez, J. A.; De Carlo, F.; Chap, B. S.; Spagnol, G.; Fleury, M.; Fortis, K.; Dorier, J.; Tissot, S.; Rusakiewicz, S.; Ferreira, H. J.; Bassani-Sternberg, M.; Swisher, E. M.; Kandalaft, L.; Mastroyannis, S. A.; Montone, K. T.; Powell, D.; Pittet, M. J.; Tanyi, J. L.; Coukos, G.; Fotopoulou, C.; Conejo-Garcia, J. R.; Dangaj Laniti, D.
10.1101/2024.05.02.590528 — immunology — Posted on 2024-05-05
4267 Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion
Perelson, A. S.; Phan, T.; Conway, J. M.; Pagane, N.; Kreig, J.; Sambaturu, N.; Iyaniwura, S.; Li, J. Z.; Ribeiro, R. M.; Ke, R.
10.1101/2024.05.03.592318 — immunology — Posted on 2024-05-05
4268 Peromyscus leucopus, Mus musculus, and humans have distinct transcriptomic responses to larval Ixodes scapularis bites
Bourgeois, J. S.; McCarthy, J. E.; Turk, S.-P.; Bernard, Q.; Clendenen, L. H.; Wormser, G. P.; Marcos, L.; Dardick, K.; Telford, S. R.; Marques, A. R.; Hu, L. T.
10.1101/2024.05.02.592193 — immunology — Posted on 2024-05-05
4270 Prediction of KIR3DL1/Human Leukocyte Antigen binding
Maiers, M.; Louzoun, Y.; Pymm, P.; Vivian, J. P.; Rossjohn, J.; Brooks, A. G.; Saunders, P. M.
10.1101/2024.05.03.592082 — immunology — Posted on 2024-05-05
4271 Clearing method adapted to FFPE tissues for 3D imaging of nerve fibers, B cells, and tertiary lymphoid structures
Azar, S.; Letaief, L.; Malkinson, G.; Martin, S.; Validire, P.; Teillaud, J.-L.; Dieu-Nosjean, M.-C.; BRUNET, I.
10.1101/2024.05.05.592575 — immunology — Posted on 2024-05-05
4274 Endothelial ERG programs neutrophil transcriptome for sustained anti-inflammatory vascular niche
Vellingiri, V.; Avin BR, V.; Joshi, J. C.; Akhter, M. Z.; Anwar, M.; Banerjee, S.; Dudek, S.; Tsukasaki, Y.; Pinho, S.; Mehta, D.
10.1101/2024.05.02.591799 — immunology — Posted on 2024-05-05
4275 Cloning and functional characterization of novel human neutralizing anti-interferon-alpha and anti-interferon-beta antibodies
Papasavvas, E.; Lu, L.; Fair, M.; Olivia, I.; Cassel, J.; Majumdar, S.; Mounzer, K. C.; Kostman, J. R.; Tebas, P.; Bar-Or, A.; Muthumani, K.; Montaner, L. J.
10.1101/2024.05.05.591636 — immunology — Posted on 2024-05-05
4276 The role of VISTA engagement in limiting neutrophil-mediated inflammation
Nowak, E. C.; Li, J.; ElTanbouly, M. A.; Davis, W. L.; Sergent, P.; Mendyka, L. K.; Lines, L.; Smits, N. C.; Mabaera, R.; Rajanna, S.; Carriere, C.; Koehn, B.; Blazar, B. A.; Burns, C. M.; Noelle, R. J.; Skopelja-Gardner, S.
10.1101/2024.05.05.592601 — immunology — Posted on 2024-05-05
4278 Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice
Vecchione, A.; Khosravi-Maharlooei, M.; Danzl, N.; Li, H. W.; Nauman, G.; Madley, R.; Waffarn, E.; Winchester, R.; Ruiz, A.; Ding, X.; Fousteri, G.; Sykes, M.
10.1101/2024.05.02.591692 — immunology — Posted on 2024-05-05
4279 Alcohol-induced sleep dysregulation in Drosophila is dependent on the neuropeptide PDF
Ramirez-Roman, M. E.; Fuenzalida-Uribe, N. L.; Ayala-Santiago, G.; Agosto, J. L.; Ghezzi, A.
10.1101/2024.05.05.592572 — neuroscience — Posted on 2024-05-05
4280 Individual variability in the relationship between physiological and resting-state fMRI metrics
Moia, S.; Chen, G.; Urunuela, E.; Stickland, R.; Termenon, M.; Caballero Gaudes, C.; Bright, M. G.
10.1101/2024.05.02.592237 — neuroscience — Posted on 2024-05-05
4283 Sleep and Activity Patterns in Autism Spectrum Disorder
Weissenkampen, J. D.; Ghorai, A.; Fasolino, M.; Gehringer, B. N.; Rajan, M.; Dow, H. C.; Sebro, R.; Rader, D. J.; Keenan, B. T.; Almasy, L.; Bucan, M.
10.1101/2024.05.02.592263 — neuroscience — Posted on 2024-05-05
4284 Hippocampal ripples mediate motor learning during brief rest breaks in humans
Sjogard, M.; Baxter, B.; Mylonas, D.; Driscoll, B.; Kwok, K.; Tolosa, A.; Thompson, M.; Stickgold, R.; Vangel, M.; Chu, C. J.; Manoach, D. S.
10.1101/2024.05.02.592200 — neuroscience — Posted on 2024-05-05
4287 Development of the overlapping network modules in the human brain
He, Y.; Lei, T.; Liao, X.; Liang, X.; Sun, L.; Xia, M.; Xia, Y.; Zhao, T.; Chen, X.; Men, W.; Wang, Y.; Ma, L.; Liu, N.; Lu, J.; Zhao, G.; Ding, Y.; Deng, Y.; Wang, J.; Chen, R.; Zhang, H.; Tan, S.; Gao, J.-H.; Qin, S.; Tao, S.; Dong, Q.
10.1101/2024.05.03.592316 — neuroscience — Posted on 2024-05-05
4288 Verbal working memory and syntactic comprehension segregate into the dorsal and ventral streams
Matchin, W.; Mollasaraei, Z. K.; Bonilha, L.; Rorden, C.; Hickok, G.; den Ouden, D.; Fridriksson, J.
10.1101/2024.05.05.592577 — neuroscience — Posted on 2024-05-05
4289 Optimized AAV capsids for diseases of the basal ganglia show robust potency and distribution in adult nonhuman primates
Leib, D. E.; Chen, Y. H.; Tecedor, L.; Ranum, P. T.; Keiser, M. S.; Lewandowshi, B. C.; Carrell, E. M.; Arora, S.; Huerta-Ocampo, I.; Liu, X.; Davidson, B. L.
10.1101/2024.05.02.592211 — neuroscience — Posted on 2024-05-05
4290 Insulin resistance compromises midbrain organoid neural activity and metabolic efficiency predisposing to Parkinsons disease pathology
Zagare, A.; Kurlovics, J.; Almeida, C.; Ferrante, D.; Frangenberg, D.; Neises, L.; Vitali, A.; Gomez-Giro, G.; Jaeger, C.; Antony, P.; Halder, R.; Krueger, R.; Glaab, E.; Meiser, J.; Stalidzans, E.; Arena, G.; Schwamborn, J. C.
10.1101/2024.05.03.592331 — neuroscience — Posted on 2024-05-05
4291 Statistical signature of subtle behavioural changes inlarge-scale behavioural assays
Blanc, A.; Laurent, F.; Barbier--Chebbah, A.; Cocanougher, B. T.; Jones, B. M. W.; Hague, P.; Zlatic, M.; Chikhi, R.; Vestergaard, C. L.; Jovanic, T.; Masson, J.-B.; Barre, C.
10.1101/2024.05.03.591825 — neuroscience — Posted on 2024-05-05
4294 Daily light-induced transcription in visual cortex neurons drives downward Firing Rate Homeostasis and stabilizes sensory processing
Kushinsky, D.; Tsivourakis, E.; Apelblat, D.; Roethler, O.; Breger-Mikulincer, M.; Cohen-Kashi, K.; Spiegel, I.
10.1101/2024.05.05.592565 — neuroscience — Posted on 2024-05-05
4295 Cardiovascular responses to natural and auditory evoked slow waves predict post-sleep cardiac function
Alessandrelli, G.; Huwiler, S.; Bernardi, G.; Carro-Dominguez, M.; Stich, F.; Sala, R.; Aziri, F.; Trippel, A.; Markendorf, S.; Niederseer, D.; Bohm, P.; Cerveri, P.; Siclari, F.; Huber, R.; Wenderoth, N.; Schmied, C.; Lustenberger, C.
10.1101/2024.05.03.592377 — neuroscience — Posted on 2024-05-05
4296 Insulin evokes release of endozepines from astrocytes of the NTS to modulate glucose metabolism
New, L. E.; Wang, N.; Khan, S.; Griffiths, J. C.; Hains, R.; Johnston, J.; Filippi, B. M.
10.1101/2024.05.03.592384 — neuroscience — Posted on 2024-05-05
4301 Invasive adult jumping worms in Atlantic Canada are chill-susceptible
Adams, V. E.; Chettiar, S. R.; Clow, T. M.; Gendron, E.; Gough, A. L.; Stewart, B. E. M.; Cameron, E. K.; Toxopeus, J.
10.1101/2024.05.02.592186 — zoology — Posted on 2024-05-05
4304 Fibre type differences in the organisation of mononuclear cells and myonuclei at the tips of human myofibres
Hoegsbjerg, C.; Moebjerg, A.; Yeung, C.-Y. C.; Schjerling, P.; Krogsgaard, M. R.; Koch, M.; Kjaer, M.; von Keudell, A. G.; Mackey, A. L.
10.1101/2024.05.03.592365 — physiology — Posted on 2024-05-05
4305 Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α
Sergienko, N. M.; Kiriazis, H.; Donner, D. G.; Trewin, A. J.; Garside, V. C.; Smith, K. A.; Raaijmakers, A. J.; Bell, J. R.; Mellor, K. M.; Delbridge, L. M.; McMullen, J. R.; Weeks, K. L.
10.1101/2024.05.05.592558 — physiology — Posted on 2024-05-05
4307 Perinatal maternal undernutrition in baboons modulates hepatic mitochondrial function but not metabolites in aging offspring.
Adekunbi, D. A.; Bowen, Y.; Huber, H. F.; Riojas, A. M.; Moody, A. J.; Li, C.; Olivier, M.; Nathanielsz, P. W.; Clarke, G. D.; Cox, L. A.; Salmon, A. B.
10.1101/2024.05.02.592246 — physiology — Posted on 2024-05-05
4311 Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel
Karlsson, E.; Anden, O.; Fan, C.; Fourati, Z.; Haouz, A.; Zhuang, Y.; Howard, R. J.; Delarue, M.; Lindahl, E.
10.1101/2024.05.02.592243 — biophysics — Posted on 2024-05-05
4312 Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM
Li, W.; Yang, H.; Stachowski, K.; Norris, A. S.; Lichtenthal, K.; Kelly, S.; Gollnick, P.; Wysocki, V. H.; Foster, M. P.
10.1101/2024.05.02.592192 — biophysics — Posted on 2024-05-05
4313 Multilevel irreversibility reveals higher-order organisation of non-equilibrium interactions in human brain dynamics
Nartallo-Kaluarachchi, R.; Bonetti, L.; Fernandez-Rubio, G.; Vuust, P.; Deco, G.; Kringelbach, M. L.; Lambiotte, R.; Goriely, A.
10.1101/2024.05.02.592195 — biophysics — Posted on 2024-05-05
4316 Adaptive optical third-harmonic generation microscopy for in vivo imaging of tissues
Rodriguez, C.; Pan, D.; Natan, R. G.; Mohr, M. A.; Miao, M.; Chen, X.; Northen, T. R.; Vogel, J. P.; Ji, N.
10.1101/2024.05.02.592275 — biophysics — Posted on 2024-05-05
4317 Salmonids exhibit an acute behavioral response to heterothermal environments
Naudascher, R.; Brizzolara, S.; Slomka, J.; Boes, R. M.; Holzner, M.; Silva, L. G. M.; Stocker, R.
10.1101/2024.05.03.592389 — biophysics — Posted on 2024-05-05
4319 Device-free isolation of photoreceptor cells from patient iPSC-derived retinal organoids
Stone, N. E.; Bohrer, L. R.; Mullin, N. K.; Cooke, J.; Wright, A. T.; Stone, E. M.; Mullins, R. F.; Tucker, B. A.
10.1101/2024.05.02.592255 — bioengineering — Posted on 2024-05-05
4320 Efficient and durable gene activation by Cas9-mediated epigenome editing in vivo
Qin, Y.; Akbulut, T.; Mandraju, R.; Connolly, K.; Bechill, J.; Assadian, F.; Shottek, A.; Levy, S.; Benoit, J.; Yamagata, T.
10.1101/2024.05.03.592438 — bioengineering — Posted on 2024-05-05
4323 HEPN-AbiV is an RNase in the antiphage system AbiV
Zhu, X.; Morency, C.; Picard, M.-E.; Mosterd, C.; McAlister, J. A.; Perrault-Jolicoeur, A.; Shi, R.; Moineau, S.
10.1101/2024.05.05.592566 — biochemistry — Posted on 2024-05-05
4325 A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24
Nyame, P.; Togami, A.; Yoshida, T.; Masunaga, T.; Begum, M. M.; Terasawa, H.; Monde, N.; Tahara, Y.; Tanaka, R.; Tanaka, Y.; Kubi, J. A.; Amesimeku, W. O.; Hossain, M. J.; Otsuka, M.; Yoshimura, K.; Ikeda, T.; Sawa, T.; Satou, Y.; Fujita, M.; Maeda, Y.; Tateishi, H.; Monde, K.
10.1101/2024.05.03.592399 — microbiology — Posted on 2024-05-05
4326 Genomic epidemiology of ESBL-producing Escherichia coli from humans and an Aotearoa New Zealand river
Gray, H. A.; Biggs, P. J.; Midwinter, A. C.; Rogers, L. E.; Fayaz, A.; Akhter, R. N.; Burgess, S. A.
10.1101/2024.05.05.592593 — microbiology — Posted on 2024-05-05
4327 Disorder regulates homeostasis of extracytoplasmic proteins in streptococci
Rahman, M. M.; Zamakhaeva, S.; Rush, J. S.; Chaton, C. T.; Kenner, C. W.; Hla, Y. M.; Tsui, H.-C. T.; Winkler, M. E.; Korotkov, K. V.; Korotkova, N.
10.1101/2024.05.05.592596 — microbiology — Posted on 2024-05-05
4328 Host-encoded DNA methyltransferases modify the epigenome and host tropism of invading phages
Takahashi, M.; Hiraoka, S.; Matsumoto, Y.; Shibagaki, R.; Ujihara, T.; Maeda, H.; Seo, S.; Nagasaki, K.; Takeuchi, H.; Matsuzaki, S.
10.1101/2024.05.05.592563 — microbiology — Posted on 2024-05-05
4329 Oxidative Stress is a shared characteristic of ME/CFS and Long COVID
Shankar, V.; Wilhelmy, J.; Michael, B.; Cervantes, L.; Mallajosyula, V.; Davis, R.; Snyder, M.; Younis, S.; Robinson, W. H.; Shankar, S.; Mischel, P.; Bonilla, H.; Davis, M.
10.1101/2024.05.04.592477 — immunology — Posted on 2024-05-05
4331 The effect of Citrus reticulata peel extract containing hesperidin on inhibition of SARS-CoV-2 infection based on pseudovirus entry assays
Septisetyani, E. P.; Harsan, H. S.; Kumara, D.; Prasetyaningrum, P. W.; Paramitasari, K. A.; Cahyani, A. D.; Anam, K.; Kastian, R. F.; Santoso, A.; Ikawati, M.; Meiyanto, E.
10.1101/2024.05.03.592493 — pharmacology and toxicology — Posted on 2024-05-05
4332 Evolutionary conserved cis-trans regulation machinery for diterpenoid phytoalexin production in Poaceae
Liu, Y.; Tomiyama, S.; Motegi, I.; Yamamoto, N.; Zheng, A.; Mori, M.; Kawahara, M.; Tsujii, Y.; Miyamoto, K.; Furumi, H.; Sato, Y.; Nojiri, H.; Okada, K.
10.1101/2024.05.05.592300 — plant biology — Posted on 2024-05-05
4335 A heterogeneous population code at the first synapse of vision
Herzog, T.; Yoshimatsu, T.; Moya-Diaz, J.; James, B.; Lagnado, L.; Baden, T.
10.1101/2024.05.03.592379 — neuroscience — Posted on 2024-05-05
4336 A phylogeny of extant coleoid cephalopods with brain data
Basava, K.; Bendixen, T.; Birk Sorensen, A. L.; George, N. L.; Vanhersecke, Z.; Omotosho, J.; Mather, J.; Muthukrishna, M.
10.1101/2024.04.29.591691 — evolutionary biology — Posted on 2024-05-05
4337 Radicle growth regulation of root parasitic plants by auxin-related compounds
Tsuzuki, K.; Suzuki, T.; Kuruma, M.; Nishiyama, K.; Hayashi, K.-i.; Hagihara, S.; Seto, Y.
10.1101/2024.05.03.592385 — plant biology — Posted on 2024-05-05
4343 Transit amplifying cells balance growth and differentiation in above-ground meristems
Joossens, J.; Herwegh, D.; Laureyns, R.; Pevernagie, J.; Van Hautegem, T.; Polaris, L.; bhattacharya, S.; Korfhage, C.; Depuydt, T.; Demuynck, K.; Vandepoele, K.; Saeys, Y.; Whipple, C.; Strable, J.; Nelissen, H.
10.1101/2024.05.04.592499 — plant biology — Posted on 2024-05-05
4345 Modification of xylan in secondary walls alters cell wall biosynthesis and wood formation programs
Sivan, P.; Urbancsok, J.; Donev, E. N.; Derba-Maceluch, M.; Barbut, F. R.; Yassin, Z.; Gandla, M. L.; Mitra, M.; Heinonen, S. E.; Simura, J.; Cermanova, K.; Karady, M.; Scheepers, G.; Jönsson, L. J.; Master, E. R.; Vilaplana, F.; Mellerowicz, E. J.
10.1101/2024.05.02.592170 — plant biology — Posted on 2024-05-05
4347 Elemental profiling and genome-wide association mapping reveal genomic variants modulating ionomic composition in Populus trichocarpa leaves
Ployet, R.; Feng, K.; Zhang, J.; Baxter, I.; Glasgow, D. C.; Chen, J.-G.; Tuskan, G. A.; Tschaplinski, T.; Weston, D. J.; Martin, M. Z.; Muchero, W.
10.1101/2024.05.03.592412 — plant biology — Posted on 2024-05-05
4348 Superhydrophobic Sand Mulch and Date Palm Biochar Dramatically Boost Growth of Moringa oleifera in Sandy Soil: Insights into Evapotranspiration Budgeting and Metabolomic Profiling
Odokonyero, K.; Vernooij, B.; Albar, B.; Exposito, L. O.; Alsamdani, A.; Haider, A. A. G.; Musskopf, N. V. H.; Kharbatia, N.; Gallo, A.; Mishra, H.
10.1101/2024.05.04.592506 — plant biology — Posted on 2024-05-05
4349 Targeted intragenic demethylation initiates chromatin rewiring for gene activation
Liu, Y. V.; Bassal, M. A.; Jayasinghe, M. K.; Lin, Q. X. X.; Wu, C. S.; Tang, J. P.; Kwon, J.; Zhou, Q.; Tan, H. K.; Ebralidze, A. K.; Le, M. T. N.; Chai, L.; Benoukraf, T.; Di Ruscio, A.; Tenen, D. G.
10.1101/2020.07.16.205922 — genetics — Posted on 2024-05-05
4352 A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria
Faniyan, T. S.; Zhang, X.; Morgan, D. A.; Robles, J.; Bathina, S.; Perry, R. J.; Brookes, P. S.; Rahmouni, K.; Chhabra, K. H.
10.1101/2023.09.01.555894 — physiology — Posted on 2024-05-05
4353 Physiological state matching in a pair bonded poison frog
Nowicki, J. P.; Rodriguez, C.; Lee, J. C.; Goolsby, B. C.; Yang, C.; Cleland, T. A.; O'Connell, L. A.
10.1101/2022.09.25.509360 — animal behavior and cognition — Posted on 2024-05-05
4355 Synchronization between chloroplastic and cytosolic protein synthesis for photosynthesis complex assembly
Fujita, T.; Wakigawa, T.; Kawamoto, N.; Kurihara, Y.; Hirose, Y.; Hirayama, T.; Toh, H.; Kuriyama, T.; Hashimoto, A.; Matsuura-Suzuki, E.; Mochida, K.; Yoshida, M.; Matsui, M.; Iwasaki, S.
10.1101/2024.05.03.592458 — molecular biology — Posted on 2024-05-05
4357 Paralogue-selective degradation of the lysine acetyltransferase EP300
Chen, X.; Crawford, M. C.; Xiong, Y.; Shaik, A. B.; Suazo, K. F.; Penikalapati, M. S.; Williams, J. H.; Andresson, T.; Swenson, R. E.; Meier, J. L.
10.1101/2024.05.03.592353 — biochemistry — Posted on 2024-05-05
4359 Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction
Ramasamy, P. K.; Matos, J. O.; Black, B. Y.; Ellenburg, W. H.; Chen, J.; Patterson, M.; Gehtman, J. A.; Theobald, D.; Krauss, I. J.; Oprian, D. D.
10.1101/2024.05.04.592530 — biochemistry — Posted on 2024-05-05
4361 Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex
Bernhard, H.; Petrzilkova, H.; Popelarova, B.; Ziemkiewicz, K.; Bartosik, K.; Warminski, M.; Tengo, L.; Gröger, H.; Dolce, L. G.; Micura, R.; Jemielity, J.; Kowalinski, E.
10.1101/2024.05.04.591051 — molecular biology — Posted on 2024-05-05
4362 Deletion of an sRNA primes development in a multicellular bacterium
La Fortezza, M.; Verwilt, J.; Cossey, S.; Eisner, S.; Velicer, G. J.; Yu, Y.-T. N.
10.1101/2024.05.04.592516 — molecular biology — Posted on 2024-05-05
4363 A metabolic atlas of mouse aging
Pilley, S. E.; Awad, D.; Latumalea, D.; Esparza, E.; Zhang, L.; Shi, X.; Unfried, M.; Wang, S.; Mulondo, R.; Kashyap, S.; Moaddeli, D.; Sajjakulnukit, P.; Sutton, D.; Wong, H.; Coakley, A.; Garcia, G.; Higuchi-Sanabria, R.; Liu, S.; Yu, B.; Tu, W. B.; Kennedy, B.; Lyssiotis, C. A.; Mullen, P. J.
10.1101/2024.05.04.592445 — molecular biology — Posted on 2024-05-05
4364 Synchronization between chloroplastic and cytosolic protein synthesis for photosynthesis complex assembly
Iwasaki, S.; Fujita, T.; Wakigawa, T.; Kawamoto, N.; Kurihara, Y.; Hirose, Y.; Hirayama, T.; Toh, H.; Kuriyama, T.; Hashimoto, A.; Matsuura-Suzuki, E.; Mochida, K.; Yoshida, M.; Matsui, M.
10.1101/2024.05.03.592458 — molecular biology — Posted on 2024-05-05
4365 A beta-Galactosidase acting on unique galactosides: the structure and function of a beta-1,2-galactosidase from Bacteroides xylanisolvens, an intestinal bacterium
Nakazawa, Y.; Kageyama, M.; Matsuzawa, T.; Liang, Z.; Kobayashi, K.; Shimizu, H.; Masuhiro, M.; Motouchi, S.; Kumano, S.; Tanaka, N.; Kuramochi, K.; Nakai, H.; Taguchi, H.; NAKAJIMA, M.
10.1101/2024.05.03.592134 — biochemistry — Posted on 2024-05-05
4366 Advancing thermostability of the key photorespiratory enzyme glycerate 3-kinase by structure-based recombination
Roze, L. V.; Antoniak, A.; Sarkar, D.; Liepman, A. H.; Tejera-Nieves, M.; Vermaas, J. V.; Walker, B. J.
10.1101/2024.05.02.592181 — biochemistry — Posted on 2024-05-05
4367 Control of 3' splice site selection by the yeast splicing factor Fyv6
Senn, K.; Lipinski, K.; Zeps, N. J.; Griffin, A. F.; Wilkinson, M. E.; Hoskins, A.
10.1101/2024.05.04.592262 — biochemistry — Posted on 2024-05-05
4370 Full factorial construction of synthetic microbial communities
Diaz-Colunga, J.; Catalan, P.; San Roman, M.; Arrabal, A.; Sanchez, A.
10.1101/2024.05.03.592148 — ecology — Posted on 2024-05-05
4371 Discovery of CRBN-dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library
Razumkov, H.; Jiang, Z.; Baek, K.; You, I.; Geng, Q.; Donovan, K.; Tang, M. T.; Metivier, R. J.; Mageed, N.; Seo, P.; Li, Z.; Byun, W. S.; Hinshaw, S. M.; Sarott, R. C.; Fischer, E. S.; Gray, N. S.
10.1101/2024.05.04.592550 — molecular biology — Posted on 2024-05-05
4372 Proteogenomic reconstruction of organ-specific metabolic networks in an environmental sentinel species, the amphipod Gammarus fossarum
Koenig, N.; Baa-Puyoulet, P.; Lafont, A.; Lorenzo Colina, I.; Navratil, V.; Lepretre, M.; Sugier, K.; Delorme, N.; Garnero, L.; Queau, H.; Gaillard, J.-C.; Kielbasa, M.; Ayciriex, S.; Calevro, F.; Arnaud, C.; Hubert, C.; Geffard, O.; Degli Esposti, D.
10.1101/2024.05.04.592373 — molecular biology — Posted on 2024-05-05
4374 Cysteine Rich Intestinal Protein 2 is a copper-Responsive regulator of skeletal muscle differentiation.
Verdejo-Torres, O.; Klein, D. C.; Novoa-Aponte, L.; Carrazco-Carrillo, J.; Bonilla-Pinto, D.; Rivera, A.; Fitisemanu, F. M.; Jimenez-Gonzalez, M.; Flinn, L.; Pezacki, A. T.; Lanzirotti, A.; Ortiz-Frade, L. A.; Chang, C.; Navea, J. G.; Blaby-Haas, C.; Hainer, S. J.; PADILLA-BENAVIDES, T.
10.1101/2024.05.03.592485 — molecular biology — Posted on 2024-05-05
4376 A large attachment organelle mediates interaction between a novel Nanobdellota archaeon YN1 and its host
Johnson, M. D.; Sakai, H.; Paul, B.; Nunorura, T.; Dalvi, S.; Mudaliyar, M.; Shepherd, D.; Shimizu, M.; Udupa, S.; Ohkuma, M.; Kurosawa, N.; Ghosal, D.
10.1101/2024.05.04.592509 — microbiology — Posted on 2024-05-05
4378 Involvement of Pf-like phages in resistance to phage infection in clinical isolates of P. aeruginosa from cystic fibrosis patients
Blasco, L.; Barrio-Pujante, A.; Lopez-Causape, C.; Arman, L.; Bleriot, I.; Pacios, O.; Fernandez-Garcia, L.; Ortiz-Cartagena, C.; Ibarguren-Quiles, C.; Canton, R.; Oliver, A.; Tomas, M.
10.1101/2024.05.03.592413 — microbiology — Posted on 2024-05-05
4379 Changes in Cerebrospinal Fluid Proteins across the Spectrum of Untreated and Treated Chronic HIV-1 Infection
Hu, Z.; Cinque, P.; Dravid, A.; Hagberg, L.; Yilmaz, A.; Zetterberg, H.; Fuchs, D.; Gostner, J.; Blennow, K.; Spudich, S.; Kincer, L.; Zhou, S.; Joseph, S. B.; Swanstrom, R.; Price, R. W.; Gisslen, M.
10.1101/2024.05.03.592451 — microbiology — Posted on 2024-05-05
4380 A temperature-sensitive and interferon-silent Sendai virus vector for CRISPR-Cas9 delivery and gene editing in primary human cells
Stevens, C. S.; Carmichael, J.; Watkinson, R.; Kowdle, S. S.; Reis, R. A.; Hamane, K.; Jang, J.; Park, A.; Pernet, O.; Khamaikawin, W.; Hong, P.; Thibault, P. A.; Gowlikar, A.; An, D. S.; Lee, B.
10.1101/2024.05.03.592383 — microbiology — Posted on 2024-05-05
4381 Skeletal Muscle Mitochondrial Dysfunction Mediated by Pseudomonas aeruginosa Quorum Sensing Transcription Factor MvfR: Reversing Effects with Anti-MvfR and Mitochondrial-Targeted Compounds
Rahme, L.; Aggarwal, S.; Singh, V. K.; Chakraborty, A.; Cha, S.; Dimitriou, A.; de Crescenzo, C. M.; Izikson, O.; Yu, L.; Plebani, R.; Tzika, A. A.
10.1101/2024.05.03.592480 — microbiology — Posted on 2024-05-05
4382 Genome-guided, field-deployable loop-mediated isothermal amplification (LAMP) assay for specific detection of Dickeya dadantii
Ludena, S. M.; Tyagi, G.; Feng, Z.; Hampson, E.; Adhikari, A.; Minaai, M.; Wong, L.; Haubner, M.; Dobhal, S.; Arizala, D.; Andreason, S. A.; Mollov, D.; Ochoa-Corona, F. M.; Bingham, J.-P.; Odani, J.; Jenkins, D.; Ma, L. M.; Fletcher, J.; Stack, J. P.; Arif, M.
10.1101/2024.05.04.592507 — microbiology — Posted on 2024-05-05
4383 Post-Transcriptional Modular Synthetic Receptors
Zhang, X.; Mille Fragoso, L. S.; Kaseniit, K. E.; Call, C. C.; Zhang, M.; Hu, Y.; Xie, Y.; Gao, X. J.
10.1101/2024.05.03.592453 — synthetic biology — Posted on 2024-05-05
4387 Exploring sex-specific neuroendocrine influences on the sensorimotor-association axis in single individuals
Serio, B.; Yilmaz, D.; Pritschet, L.; Grotzinger, H.; Jacobs, E. G.; Eickhoff, S. B.; Valk, S. L.
10.1101/2024.05.04.592501 — neuroscience — Posted on 2024-05-05
4388 Analysis of the limited M. tuberculosis accessory genome reveals potential pitfalls of pan-genome analysis approaches
Marin, M. G.; Wippel, C.; Quinones-Olvera, N.; Behruznia, M.; Jeffrey, B. M.; Harris, M.; Mann, B. C.; Rosenthal, A.; Jacobson, K. R.; Warren, R. M.; Li, H.; Meehan, C. J.; Farhat, M. R.
10.1101/2024.03.21.586149 — bioinformatics — Posted on 2024-05-04
4390 Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending
Hu, Y.; Schwab, S.; Deiss, S.; Escudeiro, P.; van Heesch, T.; Joiner, J. D.; Vreede, J.; Hartmann, M. D.; Lupas, A. N.; Alvarez, B. H.; Alva, V.; Dame, R. T.
10.1101/2023.02.26.530074 — molecular biology — Posted on 2024-05-04
4392 CRISPR-Enabled Autonomous Transposable Element (CREATE) for RNA-based gene editing and delivery
Wang, Y.; Lin, R.-Z.; Harris, M.; Lavayen, B.; Mccreedy, B.; Hofmeister, R.; Getts, D.
10.1101/2024.01.29.577809 — synthetic biology — Posted on 2024-05-04
4394 CD4+ T Cell Depletion Before Primary Dengue and/or Secondary Zika Infection Reveals Mechanistic Correlates of Antibody Functionality in Rhesus Macaques.
Serrano-Collazo, C.; Miranda, A. M.; Cruz, L. A.; Henein, S.; Sanchez-Rosado, M. R.; Alvarez, L.; Arana, T.; Martinez, M. I.; Roman, C.; Burgos, A.; de Silva, A. M.; Sariol, C. A.
10.1101/2024.02.22.580962 — immunology — Posted on 2024-05-04
4395 A gentle palette of plasma membrane dyes
Ling, J.; Liu, Y.; Fu, Y.; Liu, S.; Ding, L.; Huang, L.; Xi, P.; Chen, Z.
10.1101/2024.05.04.592408 — neuroscience — Posted on 2024-05-04
4397 Modeling Hereditary Diffuse Leukoencephalopathy with Axonal Spheroids using microglia-sufficient brain organoids
Wong, W. J.; Zhu, Y.; Wang, H.; Qian, J. W.; Li, Z.; Song, L.; Liu, Z.; Wei, G.; Zhang, S. Y.; Su, B.; Ping, H. F.; Wang, K.; Ginhoux, F.
10.1101/2024.02.12.579869 — neuroscience — Posted on 2024-05-04
4398 A theoretical basis for cell death
Himeoka, Y.; Horiguchi, S. A.; Kobayashi, T. J.
10.1101/2024.03.04.583348 — systems biology — Posted on 2024-05-04
4399 Liquid-like condensates that bind actin can polymerize and bundle actin filaments
Walker, C.; Graham, K.; Torres, A.; Wang, L.; Lafer, E. M.; Rangamani, P.; Stachowiak, J.
10.1101/2024.05.04.592527 — biophysics — Posted on 2024-05-04
4401 Reconstruction of artificial nuclei with nuclear import activity in living mouse oocytes
Yonezawa, N.; Shindo, T.; Oda, H.; Kimura, H.; Hiraoka, Y.; Haraguchi, T.; Yamagata, K.
10.1101/2024.05.03.592133 — cell biology — Posted on 2024-05-04
4402 In vivo reprogramming of Caenorhabditis elegans leads to heterogeneous effects on lifespan
Kamaludeen Mariyath, N. H.; Mauge, Y.; El Mouridi, S.; Pico, S.; Vilchez Acosta, A.; de Sousa, J. A.; Pierron, M.; Praz, V.; von Meyenn, F.; Frokjaer-Jensen, C.; Ocampo, A.
10.1101/2024.05.03.592330 — cell biology — Posted on 2024-05-04
4403 Anchorage-independent cell proliferation promoted by fascin's F-actin bundling
Isogai, T.; Murali, V. S.; Zhou, F.; Wang, X.; Rajendran, D.; Castro, L. P.; Venkateswaran, N.; Conacci-Sorrell, M.; Danuser, G.
10.1101/2024.05.04.592404 — cell biology — Posted on 2024-05-04
4404 Velociraptor: Cross-Platform Quantitative Search Using Hallmark Cell Features
Cross, C. E.; Mayeda, C.; Medina, S.; Hayes, M. J.; Kaviany, S.; Connelly, J. A.; Rathmell, J. C.; Weaver, K. D.; Thompson, R. C.; Chambless, L. B.; Ihrie, R. A.; Irish, J. M.
10.1101/2024.05.01.591375 — systems biology — Posted on 2024-05-04
4405 Elucidating the Impact of Hypericum alpestre Extract and L-NAME on the PI3K/Akt Signaling Pathway in A549 Lung Adenocarcinoma Cells
Javrushyan, H.; Ginovyan, M.; Petrosyan, G.; Qocharyan, M.; Harutyunyan, T.; Gevorgyan, S.; Karabekian, Z.; Maloyan, A.; Avtandilyan, N.
10.1101/2024.05.02.592167 — cancer biology — Posted on 2024-05-04
4409 PATHOGEN GROWTH AND VIRULENCE DYNAMICS DRIVE THE HOST EVOLUTION AGAINST COINFECTIONS
Seal, S.; Basu, D. N.; Ghosh, K.; Ramachandran, A.; Kutum, R.; Shelke, T. N.; Gupta, I.; Khan, I.
10.1101/2024.05.01.592035 — evolutionary biology — Posted on 2024-05-04
4411 Extracellular Vimentin is a Damage-Associated Molecular Pattern Protein Serving as an Agonist of TLR4 in Human Neutrophils
Suprewicz, L.; Fiedoruk, K.; Sklodowski, K.; Zakrzewska, M.; Walewska, A.; Deptula, P.; Lesiak, A.; Okla, S.; Galie, P.; Patteson, A. E.; Janmey, P.; Bucki, R.
10.1101/2024.05.02.592157 — immunology — Posted on 2024-05-04
4412 Jointly efficient encoding and decoding in neural populations
Blanco Malerba, S.; Micheli, A.; Woodford, M.; Azeredo da Silveira, R.
10.1101/2023.06.21.545848 — neuroscience — Posted on 2024-05-04
4413 Sliding Window INteraction Grammar (SWING): a generalized interaction language model for peptide and protein interactions
Omelchenko, A. A.; Siwek, J. C.; Chhibbar, P.; Arshad, S.; Nazarali, I.; Nazarali, K.; Rosengart, A.; Rahimikollu, J.; Tilstra, J.; Shlomchik, M. J.; Koes, D. R.; Joglekar, A. V.; Das, J.
10.1101/2024.05.01.592062 — systems biology — Posted on 2024-05-04
4415 PROPEL: a scalable model for postbaccalaureate training to promote diversity in the biomedical workforce
Allen, J.; Abdiwahab, E.; Morris, M. D.; Le Saux, C. J.; Betancur, P.; Ansel, K. M.; Hernandez, R. D.; Nystul, T. G.
10.1101/2024.05.01.592104 — scientific communication and education — Posted on 2024-05-04
4417 Predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts
Szadai, L.; Bartha, A.; Parada, I. P.; Lakatos, A.; Pal, D.; Lengyel, A. S.; Almeida, N. P. d.; Janosi, A. J.; Nogueira, F.; Szeitz, B.; Doma, V.; Woldmar, N.; Guedes, J.; Ujfaludi, Z.; Pahi, Z. G.; Pankotai, T.; Kim, Y.; Gyorffy, B.; Baldetorp, B.; Welinder, C.; Szasz, A. M.; Betancourt, L.; Gil, J.; Appelqvist, R.; Kwon, H.-J.; Karpati, S.; Kuras, M.; Murillo, J. R.; Nemeth, I. B.; Malm, J.; Fenyo, D.; Pawlowski, K.; Horvatovich, P.; Wieslander, E.; Kemeny, L. V.; Domont, G.; Marko-Varga, G.; Sanchez, A.
10.1101/2024.05.01.592032 — cancer biology — Posted on 2024-05-04
4424 Deep Mutagenesis of a Transporter for Uptake of a Non-Native Substrate Identifies Conformationally Dynamic Regions
Ellis, H. J.; Chan, M.; Selvam, B.; Walter, E.; Devlin, C. A.; Szymanski, S. K.; Henry, L. K.; Shukla, D.; Procko, E.
10.1101/2021.04.19.440442 — biochemistry — Posted on 2024-05-04
4425 Pathway-enhanced Transformer-based robust model for quantifying cell types of origin of cell-free transcriptome
Yan, S.; Tian, X.; Qin, Y.; Li, J.; Yang, T.; Yu, D.; Liu, W.; Sun, J.; Hu, C.; Zhou, Q.; Liu, Z.; Wang, W.-J.
10.1101/2024.02.28.582494 — bioinformatics — Posted on 2024-05-04
4426 Intracellular Tau Fragment Droplets Serve as Seeds for Tau Fibrils
Soeda, Y.; Yoshimura, H.; Bannai, H.; Koike, R.; Shiiba, I.; Takashima, A.
10.1101/2023.09.10.557018 — cell biology — Posted on 2024-05-04
4427 N-Terminus of Drosophila Melanogaster MSL1 Is Critical for Dosage Compensation
Babosha, V.; Klimenko, N.; Revel-Muroz, A.; Tikhonova, E.; Georgiev, P.; Maksimenko, O.
10.1101/2020.11.11.378323 — molecular biology — Posted on 2024-05-04
4428 Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study
Srinivasan, V.; Bao, N. L. H.; Vinh, D. N.; Thanh Hoang Le, N.; Thu, D. D.; Quang, N. L.; Trieu, L. P. T.; Nhung, H. N.; Ha, V. T. N.; Thai, P. V. K.; Ha, D. T. M.; Lan, N. H.; Caws, M.; Thwaites, G. E.; Javid, B.; Thuong, N. T.
10.1101/2023.11.22.568240 — microbiology — Posted on 2024-05-04
4429 "Dark taxonomy": a new protocol for overcoming the taxonomic impediments for dark taxa and broadening the taxon base for biodiversity assessment
Meier, R.; Srivathsan, A.; Oliveira, S. S.; Balbi, M. I. P. A.; Ang, Y.; Yeo, D.; Kjaerandsen, J.; Amorim, D. d. S.
10.1101/2023.08.31.555664 — zoology — Posted on 2024-05-04
4432 Acetylcholine demixes heterogeneous dopamine signals for learning and moving
Jang, H. J.; McMahon Ward, R.; Golden, C. E. M.; Constantinople, C. M.
10.1101/2024.05.03.592444 — neuroscience — Posted on 2024-05-04
4433 Protective role of parenthood on age-related brain function in mid- to late-life
Orchard, E. R.; Chopra, S.; Ooi, L. Q. R.; Chen, P.; An, L.; Jamadar, S. D.; Yeo, B. T. T.; Rutherford, H. J. V.; Holmes, A. J.
10.1101/2024.05.03.592382 — neuroscience — Posted on 2024-05-04
4435 Dorsal prefrontal cortex drives perseverative behavior in mice
Lebedeva, A.; Wang, Y.; Funnell, L.; Terry, B.; Oh, J.; Miller, K.; Harris, K. D.
10.1101/2024.05.02.592241 — neuroscience — Posted on 2024-05-04
4440 Filter-aided extracellular vesicle enrichment (FAEVEr) for proteomics
Pauwels, J.; Van de Steene, T.; Van de Velde, J.; De Pauw, D.; De Muyer, F.; Baeke, F.; Eyckerman, S.; Gevaert, K.
10.1101/2023.07.06.547926 — biochemistry — Posted on 2024-05-03
4441 Multi-SpinX: An Advanced Framework for Automated Tracking of Mitotic Spindles and Kinetochores in Multicellular Environments
Chai, B.; Efstathiou, C.; Choudhury, M.; Kuniyasu, K.; Jain, S. S.; Maharea, A.-C.; Tanaka, K.; Draviam, V. M.
10.1101/2024.04.03.587736 — cell biology — Posted on 2024-05-03
4443 Characterizing nascent transcription patterns of PROMPTs, eRNAs, and readthrough transcripts in the ENCODE4 deeply profiled cell lines
McShane, A.; Venkata Narayanan, I.; Paulsen, M. T.; Ashaka, M.; Blinkiewicz, H.; Yang, N. T.; Magnuson, B.; Bedi, K.; Wilson, T. E.; Ljungman, M.
10.1101/2024.04.09.588612 — molecular biology — Posted on 2024-05-03
4445 IL-2 enhances effector function but suppresses follicular localization of CD8+ T cells in chronic infection
Chen, Y.; Zhou, P.; Gubser, P. M.; Leong, Y. A.; He, J.; Wei, Y.; Makota, F. V.; Pazhouhandeh, M.; Zheng, T.; Yunis, J.; Li, Z.; Kallies, A.; Yu, D.
10.1101/2024.05.02.592184 — immunology — Posted on 2024-05-04
4446 Neural circuit basis of adolescent THC-induced potentiation of opioid responses in adult mice
Hubbard, E.; Galinato, V. M.; Derdeyn, P.; Bartas, K.; Mahler, S. V.; Beier, K. T.
10.1101/2024.04.23.590773 — neuroscience — Posted on 2024-05-03
4447 Community assessment of methods to deconvolve cellular composition from bulk gene expression
White, B. S.; de Reynies, A.; Newman, A. M.; Waterfall, J. J.; Lamb, A.; Petitprez, F.; Lin, Y.; Yu, R.; Guerrero-Gimenez, M. E.; Domanskyi, S.; Monaco, G.; Chung, V.; Banerjee, J.; Derrick, D.; Valdeolivas, A.; Li, H.; Xiao, X.; Wang, S.; Zheng, F.; Yang, W.; Catania, C. A.; Lang, B. J.; Bertus, T. J.; Piermarocchi, C.; Caruso, F. P.; Ceccarelli, M.; Yu, T.; Guo, X.; Bletz, J.; Coller, J.; Maecker, H.; Duault, C.; Sokoohi, V.; Patel, S.; Liliental, J. E.; Simon, S.; Tumor Deconvolution DREAM Challenge consortium, ; Saez-Rodriguez, J.; Heiser, L. M.; Guinney, J.; Gentles, A. J.
10.1101/2022.06.03.494221 — bioinformatics — Posted on 2024-05-03
4448 HaloTag display enables quantitative single-particle characterization and functionalization of engineered extracellular vesicles
Mitrut, R. E.; Stranford, D. M.; DiBiase, B. N.; Chan, J. M.; Bailey, M. D.; Luo, M.; Harper, C. S.; Meade, T. J.; Wang, M.; Leonard, J. N.
10.1101/2023.09.25.559433 — bioengineering — Posted on 2024-05-03
4449 The landscape of regional missense mutational intolerance quantified from 125,748 exomes
Chao, K. R.; Wang, L.; Panchal, R.; Liao, C.; Abderrazzaq, H.; Ye, R.; Schultz, P.; Compitello, J.; Grant, R. H.; Kosmicki, J. A.; Weisburd, B.; Phu, W.; Wilson, M. W.; Laricchia, K. M.; Goodrich, J. K.; Goldstein, D.; Goldstein, J. I.; Vittal, C.; Poterba, T.; Baxter, S.; Watts, N. A.; Solomonson, M.; gnomAD consortium, ; Tiao, G.; Rehm, H. L.; Neale, B. M.; Talkowski, M. E.; MacArthur, D. G.; O'Donnell-Luria, A.; Karczewski, K. J.; Radivojac, P.; Daly, M. J.; Samocha, K. E.
10.1101/2024.04.11.588920 — genomics — Posted on 2024-05-03
4450 Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems
Rydhmer, K.; Eckberg, J. O.; Lundgren, J. G.; Jansson, S.; Still, L.; Quinn, J. E.; Washington, R.; Lemmich, J.; Nikolajsen, T.; Sheller, N.; Michels, A. M.; Bredeson, M. M.; Rosenzweig, S. T.; Bick, E. N.
10.1101/2023.08.15.553397 — ecology — Posted on 2024-05-03
4453 Structure of a human monoclonal antibody in complex with Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi
Rudolph, M.; Chen, Y.; Vorauer, C.; Vance, D.; Piazza, C. L.; Willsey, G. G.; McCarthy, K.; Muriuki, B.; Cavacini, L.; Guttman, M.; Mantis, N. J.
10.1101/2024.04.29.591597 — immunology — Posted on 2024-05-03
4457 Pools of independently cycling inositol phosphates revealed by pulse labeling with 18O-water
Kim, G.; Liu, G.; Qiu, D.; Gopaldass, N.; De Leo, G.; Hermes, J.; Timmer, J.; Mayer, A.; Jessen, H.
10.1101/2024.05.03.592351 — biochemistry — Posted on 2024-05-03
4459 DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects
Colomer-Boronat, A.; Knol, L. I.; Peris, G.; Sanchez, L.; Peluso, S.; Tristan-Ramos, P.; Gazquez-Gutierrez, A.; Chin, P.; Gordon, K.; Barturen, G.; Hill, R. E.; Garcia-Perez, J. L.; Ivens, A.; Macias, S.; Heras, S. R.
10.1101/2024.05.02.592145 — molecular biology — Posted on 2024-05-03
4462 TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress.
Hwang, S.-P.; Liao, H.; Barondeau, K.; Han, X.; Herbert, C.; McConnie, H.; Shekar, A.; Pestov, D.; Limbach, P. A.; Chang, J. T.; Denicourt, C.
10.1101/2024.05.02.591343 — molecular biology — Posted on 2024-05-03
4466 Variable patterns of retrotransposition in different HeLa strains provide mechanistic insights into SINE RNA mobilization processes
Moldovan, J. B.; Kopera, H. C.; Liu, Y.; Garcia-Canadas, M.; Catalina, P.; Leone, P. E.; Kitzman, J. O.; Kidd, J. M.; Garcia-Perez, J. L.; Moran, J.
10.1101/2024.05.03.592410 — molecular biology — Posted on 2024-05-03
4469 Decoding scalp health and microbiome dysbiosis in dandruff
Rasheedkhan Regina, V.; Chopra, T.; Weihao, K.; Cheruvalli, S.; Sabrina, A.; Fatimah Jamal Mohamed, H. B.; Ramasamy, K. P.; Sarah, K.; Chong, Y. Y.; Kaliyamoorthi, E.; Williams, R.; Liu, X.; Krishna, V.; Bourokba, N.; Jhingan, A.; Thng Tien Guan, S.; Da Cruz, O.; Riu, S.; De Dormael, R.; Abed, K.; Touriguine, O.; Jourdain, R.; Cupferman, S.; Aguilar, L.; A. Rice, S.
10.1101/2024.05.02.592279 — microbiology — Posted on 2024-05-03
4471 Facultative endosymbiosis between cellulolytic protists and methanogenic archaea in the gut of the Formosan termite Coptotermes formosanus
Kaneko, M.; Omori, T.; Igai, K.; Mabuchi, T.; Sakai-Tazawa, M.; Nishihara, A.; Kihara, K.; Yoshimura, T.; Ohkuma, M.; Hongoh, Y.
10.1101/2024.05.03.592298 — microbiology — Posted on 2024-05-03
4474 Molecular characterisation of Streptococcus pyogenes (StrepA) non-invasive isolates during the 2022-23 UK upsurge
Hall, J. N.; Bah, S. Y.; Khalid, H. O.; Brailey, A.; Coleman, S.; Kirk, T.; Hussain, N.; Tovey, M.; Chaudhuri, R. R.; Davies, S.; Tilley, L.; de Silva, T.; Turner, C. E.
10.1101/2024.05.02.592214 — microbiology — Posted on 2024-05-03
4476 Determinants of the Divergent Salmonella and Shigella Epithelial Colonization Strategies Resolved in Human Enteroids and Colonoids
Geiser, P.; Di Martino, M. L.; Lopes, A. C. C.; Bergholtz, A.; Sundbom, M.; Skogar, M.; Graf, W.; Webb, D.-L.; Hellstrom, P. M.; Eriksson, J.; Sellin, M. E.
10.1101/2024.05.03.592388 — microbiology — Posted on 2024-05-03
4478 Rationally Designed Pooled CRISPRi-seq Uncovers a Novel Inhibitor of Bacterial Peptidyl-tRNA Hydrolase
Rahman, A. S. M. Z.; Syroegin, E. A.; Novomisky Nechcoff, J.; Timmerman, L.; Devarajan, A.; Polikanov, Y. S.; Cardona, S. T.
10.1101/2024.05.02.592284 — microbiology — Posted on 2024-05-03
4482 Humidity determines penetrance of a latitudinal gradient in genetic selection on the microbiota by Drosophila melanogaster
Massey, C.; Nosker, M. E.; Gale, J.; Scott, S.; Walker, C. J.; Cluff, A. J.; Wilcox, S.; Morrison, A.; Morgan, S. J. G.; Beltz, J.; Schmidt, P.; Chaston, J.
10.1101/2024.05.02.591907 — microbiology — Posted on 2024-05-03
4486 Uterus and cervix anatomical changes and cervix stiffness evolution throughout pregnancy
Louwagie, E. M.; Russell, S. R.; Hairston, J. C.; Nottman, C.; Nhan-Chang, C.-L.; Fuchs, K.; Gyamfi-Bannerman, C.; Booker, W.; Andrikopoulou, M.; Friedman, A.; Zork, N.; Wapner, R.; Vink, J.; Mourad, M.; Feltovich, H.; House, M.; Myers, K.
10.1101/2024.05.01.592023 — bioengineering — Posted on 2024-05-03
4491 Modifiers of genetic dominance at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical gene silencing pathways
Batista, R. A.; Durand, E.; Mörchen, M.; Azevedo-Favory, J.; Simon, S.; Dubin, M.; Kumar, V.; Lacoste, E.; Cruaud, C.; Blassiau, C.; Barois, M.; Holl, A.-C.; Ponitzki, C.; Faure, N.; Marande, W.; Vautrin, S.; Fobis-Loisy, I.; Aury, J.-M.; Legrand, S.; Krämer, U.; Lagrange, T.; Vekemans, X.; Castric, V.
10.1101/2024.05.01.591913 — plant biology — Posted on 2024-05-03
4495 Moderating heritability with genomic data
Benstock, S. E.; Prom-Wormley, E.; Verhulst, B.
10.1101/2024.05.01.591940 — genomics — Posted on 2024-05-03
4499 An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplant
Lee, R. A.; Chopra, D. G.; Nguyen, V.; Huang, X.-P.; Zhang, Y.; Shariati, K.; Yiv, N.; Schugar, R.; Annes, J.; Roth, B. L.; Ku, G.
10.1101/2024.05.01.591950 — cell biology — Posted on 2024-05-03
4500 Antibody responses in Klebsiella pneumoniae bloodstream infection: a cohort study
Hwang, W.; Wantuch, P. L.; Bernshtein, B.; Zhiteneva, J.; Slater, D.; Vater, K. H.; Sridhar, S.; Oliver, E.; Roach, D. J.; Rao, S.; Turbett, S. E.; Knoot, C. J.; Harding, C. M.; Amin, M. N.; Cross, A. S.; LaRocque, R. C.; Rosen, D. A.; Harris, J. B.
10.1101/2024.05.01.591958 — microbiology — Posted on 2024-05-03
4501 Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes
Thirman, H. L.; Hayes, M. J.; Brown, L. E.; Porco, J. A.; Irish, J. M.
10.1101/2024.05.01.591362 — systems biology — Posted on 2024-05-03
4504 VGLL2 and TEAD1 fusion proteins drive YAP/TAZ-independent transcription and tumorigenesis by engaging p300
Guo, S.; Hu, X.; Cotton, J. L.; Ma, L.; Li, Q.; Cui, J.; Wang, Y.; Thakare, R. P.; Tao, Z.; Ip, T.; Wu, X.; Wang, J.; Mao, J.
10.1101/2024.05.01.592016 — cancer biology — Posted on 2024-05-03
4508 Virome responses to heating of a forest soil suggest that most dsDNA viral particles do not persist at 90°C
Geonczy, S. E.; Hillary, L. S.; Santos-Medellin, C.; Sorensen, J. W.; Fudyma, J. D.; Emerson, J. B.
10.1101/2024.05.01.592093 — genomics — Posted on 2024-05-03
4509 Flat-field superresolution structured illumination microscopy with joint temporal-spatial light modulation
Liang, Y.; Wen, G.; Zhang, J.; Li, S.; Tan, Y.; Jin, X.; Wang, L.; Chen, X.; Gao, J.; Li, H.
10.1101/2024.05.01.591776 — cell biology — Posted on 2024-05-03
4510 Structural characterization of antibody-responses from Zolgensma treatment provides the blueprint for the engineering of an AAV capsid suitable for redosing
Mietzsch, M.; Nelson, A. R.; Hsi, J.; Zachary, J.; Potts, L.; Chipman, P.; Ghanem, M.; Khandekar, N.; Alexander, I. E.; Logan, G. J.; Huiskonen, J. T.; McKenna, R.
10.1101/2024.05.01.590489 — immunology — Posted on 2024-05-03
4511 Dual role of BdMUTE during stomatal development in the model grass Brachypodium distachyon
Spiegelhalder, R. P.; Berg, L. S.; Nunes, T. D.; Dörr, M.; Jesenofsky, B.; Lindner, H.; Raissig, M. T.
10.1101/2024.05.01.592049 — plant biology — Posted on 2024-05-03
4512 When the liver is in poor condition, so is the heart - cardiac remodelling in MASH mouse models
Bott, S.; Lallement, J.; Marino, A.; Daskalopoulos, E. P.; Beauloye, C.; Esfahani, H.; Dessy, C.; Leclercq, I.
10.1101/2024.05.01.592038 — physiology — Posted on 2024-05-03
4515 The prevalent NR2E3 c.932G>A mutation induces aberrant splicing that can be rescued using splice-shifting antisense oligonucleotides
Sztainberg, Y.; David Teitelbaum, M.; Buchumenski, I.; Porath, H.; Sharon, D.; Banin, E.; Karni, R.; Levanon, E. Y.; Feiglin, A.
10.1101/2024.05.01.592034 — genomics — Posted on 2024-05-03
4516 Subcellular imaging of lipids and sugars using genetically encoded proximity sensors
Moore, W. M.; Brea, R. J.; Knittel, C.; Wrightsman, E.; Hui, B.; Loui, J.; Ancajas, C. F.; Best, M. D.; Devaraj, N. K.; Budin, I.
10.1101/2024.05.01.592120 — cell biology — Posted on 2024-05-03
4517 PAN deadenylase is required for mitosis in response to microtubule stress in yeast and humans
Verma, J.; He, Z.; Brown, J. A. R.; Dean, P.; Young, B.; Flibotte, S.; Howe, L. J.; Maxwell, C.; Roskelley, C.; Loewen, C.
10.1101/2024.05.01.591760 — cell biology — Posted on 2024-05-03
4518 In-silico study of fatty acid biosynthesis pathway enzymes in microalga Scenedesmus
Sharma, H. K.; Velazquez, M. B.; Marchetti, N.; Busi, M. V.; Barchiesi, J.; Nag Dasgupta, C.
10.1101/2024.05.01.592012 — plant biology — Posted on 2024-05-03
4522 Managed honey bee colony losses and causes during the active beekeeping season 2022/2023 in nine Sub-Saharan African countries
Nganso, B. T.; Ayalew, W.; Wubie, A. J.; Assefa, F.; Belayhun, L.; Ndungu, N. N.; Toroitich, D.; Otieno-Ayayo, Z. N.; Wambua, M. B.; Oyieyo, Y. O.; Elie, N.; Sikirou, R.; Idrissou, S. B.; Mwiza, W.; Turner, S.; Bobadoye, B. O.; Fameni, S. T.; Gaboe, S.; Agbodzavu, M. K.; Mafwila, P.; Tasse Taboue, G. C.; Emily, K.; Henri, T. Z. E.; Niassy, S.; Fonkou, S. N.; Pirk, C. W. W.; Gray, A.; Brodschneider, R.; Soroker, V.; Subramanian, S.
10.1101/2024.04.30.591982 — zoology — Posted on 2024-05-03
4524 Monitoring biodiversity in the global change era: The importance of herbaria and genetic diversity
Viveiros-Moniz, M.; Garcia-Munoz, A.; Matias, L.; Abdelaziz, M.; Munoz-Pajares, A. J.
10.1101/2024.05.01.591834 — plant biology — Posted on 2024-05-03
4525 Fast skeletal myosin binding protein-C expression exacerbates dysfunction in heart failure
McNamara, J.; Song, T.; Alam, P.; Binek, A.; Singh, R.; Nieman, M.; Koch, S.; Ivey, M.; Lynch, T.; Rubinstein, J.; Jin, J. P.; Lorenz, J.; Van Eyk, J.; Kanisicak, O.; Sadayappan, S.
10.1101/2024.04.30.591979 — physiology — Posted on 2024-05-03
4527 Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer
Williams, M. J.; Oliphant, M. U.; Au, V.; Liu, C.; Baril, C.; O'Flanagan, C.; Lai, D.; Beatty, S.; Van Vliet, M.; Liu, J. C.; O'Connor, L.; Goh, W. L.; Pollaci, A.; Weiner, A. C.; Grewal, D.; McPherson, A.; Moore, M.; Prabhakar, V.; Agarwal, S.; Garber, J. E.; Dillon, D.; Shah, S. P.; Brugge, J.; Aparicio, S.
10.1101/2024.05.01.591587 — cancer biology — Posted on 2024-05-03
4528 Single-Cell Transcriptomic Analysis of Kaposi Sarcoma
Rauch, D. A.; Valino Ramos, P.; Khanfar, M.; Harding, J.; Joseph, A.; Griffith, O.; Griffith, M.; Ratner, L.
10.1101/2024.05.01.592010 — cancer biology — Posted on 2024-05-03
4529 Cross-site harmonization of diffusion MRI data without matched training subjects
De Luca, A.; Swartenbroekx, T.; Seelaar, H.; van Swieten, J. C.; Cetin Karayumak, S.; Rathi, Y.; Pasternak, O.; Jiskoot, L. C.; Leemans, A.
10.1101/2024.05.01.591994 — bioinformatics — Posted on 2024-05-03
4531 PlasEval: a framework for comparing and evaluating plasmid detection tools
Mane, A.; Sanderson, H.; White, A. P.; Zaheer, R.; Beiko, R. G.; Chauve, C.
10.1101/2024.04.30.591963 — bioinformatics — Posted on 2024-05-03
4536 Ancient cyanobacterial proto-circadian clock adapted to short day-night cycles ~ 0.95 billion years ago
Li, S.; Zhou, Z.; Wan, Y.; Jia, X.; Wang, P.; Wang, Y.; Dong, S.; He, J.; Wang, X.; Qin, X.; Xie, Q.; Xu, X.; Zhao, Y.; Liang, D.; Zhang, P.; Zhang, Q.; Guo, J.
10.1101/2024.04.30.591965 — evolutionary biology — Posted on 2024-05-03
4537 Reproductive and ecological adaptations to climate underpin the evolution of sociality in lizards
Halliwell, B.; O'Connor, E. A.; Uller, T.; Meiri, S.; Holland, B.; Cornwallis, C. K.; While, G.
10.1101/2024.05.01.592000 — evolutionary biology — Posted on 2024-05-03
4538 The climatic determinants of flexible reproductive seasonality in Africa-dwelling papionins
Dezeure, J.; Dagorrette, J.; Burtschell, L.; Chowdhury, S.; Lukas, D.; Swedell, L.; Huchard, E.
10.1101/2024.05.01.591991 — evolutionary biology — Posted on 2024-05-03
4539 Rapid adaptive evolution of microbial thermal performance curves
Liu, M. H.; Han, Z.-Y.; Yuan, Y.; DeWitt, K.; Wieczynski, D. J.; Yammine, K. M.; Yammine, A.; Zufall, R.; Siepielski, A.; Chalker, D.; Onishi, M.; Machado, F. A.; Gibert, J. P.
10.1101/2024.04.30.590804 — ecology — Posted on 2024-05-03
4541 ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology
Simpson, C. L.; Tiwaa, A.; Zaver, S. A.; Johnson, C. J.; Chu, E. Y.; Harms, P. W.; Gudjonsson, J. E.
10.1101/2024.04.30.591953 — cell biology — Posted on 2024-05-03
4542 Extruded alginate tubes with myogenic potential
Lenneman, C. M.; Rose, E. M.; Strawska, B. A.; Tyszkiewicz, N. A.; Dean-Christie, K.; Katz, E.; Roche, J. M.; de Morree, A.; Roche, R.; Tulapurkar, M. E.; Roche, J. A.
10.1101/2024.04.30.591971 — cell biology — Posted on 2024-05-03
4543 UNG-RPA interaction governs the choice between high-fidelity and mutagenic uracil repair
Mu, Y.; Chen, Z.; Plummer, J. B.; Zelazowska, M. A.; Dong, Q.; Krug, L. T.; McBride, K. M.
10.1101/2024.04.30.591927 — immunology — Posted on 2024-05-03
4544 Small Extracellular Vesicle Signaling and Mitochondrial Transfer Reprograms T Helper Cell Function in Human Asthma
Hough, K. P.; Trevor, J. L.; Chacko, B. K.; Strenkowski, J. G.; Wang, Y.; Goliwas, K. F.; Bone, N. B.; Kim, Y.-i.; Holmes, R.; Vang, S.; Pritchard, A.; Chin, J.; Bodduluri, S.; Antony, V. B.; Tousif, S.; Athar, M. S.; Chanda, D.; Mitra, K.; Zmijewski, J.; Zhang, J.; Duncan, S. R.; Thannickal, V. J.; Gabrielsson, S.; Darley-Usmar, V. M.; Deshane, J. S.
10.1101/2024.04.30.589227 — immunology — Posted on 2024-05-03
4547 GIBBERELLIN SIGNALING THROUGH RGA SUPPRESSES GCN5 EFFECT ON STAMEN ELONGATION OF ARABIDOPSIS FLOWERS
Balouri, C.; Poulios, S.; Tsompani, D.; Spyropoulou, Z.; Ketikoglou, M.-C.; Kaldis, A.; Doonan, J. H.; Vlachonasios, K.
10.1101/2024.04.30.591935 — plant biology — Posted on 2024-05-03
4549 RV-specific Targeting of Snai1 Rescues Pulmonary Hypertension-induced Right Ventricular Failure by Inhibiting EndMT and Fibrosis via LOXL2 Mediated Mechanism
Banerjee, S.; Onwunyi, V. R. C.; Hong, J.; Martineau, S.; Fishbein, G. A.; Bonnet, S. B.; Provencher, S.; Bonnet, S.; Umar, S.
10.1101/2024.04.30.591766 — physiology — Posted on 2024-05-03
4551 Fusarium Protein Toolkit: AI-powered tools to combat fungal threats to agriculture
Kim, H.-S.; Haley, O. C.; Portwood, J. L.; Harding, S.; Proctor, R. H.; Woodhouse, M. R.; Sen, T. Z.; Andorf, C. M.
10.1101/2024.04.30.591916 — bioinformatics — Posted on 2024-05-03
4554 Time-Domain Diffuse Optical Tomography for Precision Neuroscience
Chekin, Y.; Decker, D.; Dehghani, H.; Dubois, J.; Field, R. M.; Gopalakrishnan, V.; Koch, E. M.; Lerner, G.; Aghajan, Z. M.; Miller, N.; Olvera, I.; Patel, M. J.; Perdue, K. L.; Schmidt, J.; Szczepanski, V.
10.1101/2024.04.30.591765 — bioengineering — Posted on 2024-05-03
4555 Forest edge landscape context affects mosquito community composition and risk of pathogen emergence
Hendy, A.; Fe, N. F.; Pedrosa, I.; Girao, A.; Figueira dos Santos, T. N.; Mendonca, C. R.; Andes Junior, J. T.; Assuncao, F. P.; Costa, E. R.; Sluydts, V.; Gordo, M.; Scarpassa, V. M.; Buenemann, M.; Lacerda, M. V. G. d.; Mourao, M. P. G.; Vasilakis, N.; Hanley, K. A.
10.1101/2024.04.30.591911 — ecology — Posted on 2024-05-03
4556 PEX39 facilitates the peroxisomal import of PTS2 proteins
Chen, W. W.; Rodrigues, T. A.; Wendscheck, D.; Pedrosa, A. G.; Yang, C.; Francisco, T.; Mocklinghoff, T.; Zografakis, A.; Nunes-Silva, B.; Avraham, R. E.; Silva, A. R.; Ferreira, M. J.; Das, H.; Bender, J.; Oeljeklaus, S.; Sondhi, V.; Schuldiner, M.; Zalckvar, E.; Hofmann, K.; Waterham, H. R.; DeBerardinis, R. J.; Azevedo, J. E.; Warscheid, B.
10.1101/2024.04.30.591961 — cell biology — Posted on 2024-05-03
4557 Condensin II activation by M18BP1
Borsellini, A.; Conti, D.; Cutts, E.; Harris, R. J.; Walstein, K.; Graziadei, A.; Cecatiello, V.; Aarts, T. F.; Xie, R.; Mazouzi, A.; Sen, S.; Hoencamp, C.; Pleuger, R.; Ghetti, S.; Oberste-Lehn, L.; Pan, D.; Bange, T.; Haarhuis, J. H. I.; Perrakis, A.; Brummelkamp, T. R.; Rowland, B.; Musacchio, A.; Vannini, A.
10.1101/2024.05.02.592151 — cell biology — Posted on 2024-05-03
4559 Distinct effects of CDK8 module subunits on cellular growth and proliferation in Drosophila
Li, X.; Liu, M.; Xing, Y.; Niu, Y.; Liu, T.-H.; Sun, J. L.; Liu, Y.; Hemba-Waduge, R.-U.-S.; Ji, J.-y.
10.1101/2024.04.30.591924 — cell biology — Posted on 2024-05-03
4561 Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
Francavilla, R.; Chattopadhyaya, B.; Damo Kamda, J. L.; Jadhav, V.; Kourrich, S.; Michaud, J. L.; Di Cristo, G.
10.1101/2024.02.27.582362 — neuroscience — Posted on 2024-05-03
4563 Waves of light at the bottom of the ocean: insights into the luminous systems of three Pennatuloidea (Anthozoa)
Duchatelet, L.; Galeazzo, G. A.; Coubris, C.; Bridoux, L.; Rezsohazy, R.; Melo, M. R. S.; Marek, M.; Dupont, S.; Oliveira, A. G.; Delroisse, J.
10.1101/2024.04.30.591678 — zoology — Posted on 2024-05-03
4567 Favorable histo-molecular remodeling of pancreatic ductal adenocarcinoma after Total Neoadjuvant Therapy including Stereotactic Body Radiotherapy
Bouchart, C.; Senar, O. A.; Navez, J.; Verset, L.; Boisson, A.; Hein, M.; Stosic, K.; Quertinmont, E.; Tafciu, V.; Zhao, S.; Mas, L.; D'Haene, N.; Van Gestel, D.; Moretti, L.; Rooman, I.; Detours, V.; Bachet, J.-B.; Demetter, P.; Willard-Gallo, K.; Nicolle, R.; Arsenijevic, T.; Van Laethem, J.-L.
10.1101/2024.04.30.591890 — cancer biology — Posted on 2024-05-03
4568 Identification and validation of drugs for repurposing in Glioblastoma: a computational and experimental workflow
Gonzalez, N.; Perez Kuper, M.; Garcia Fallit, M.; Pena Agudelo, J.; Nicola Candia, A.; Suarez Velandia, M.; Videla-Richardson, G.; Candolfi, M.
10.1101/2024.04.29.589520 — cancer biology — Posted on 2024-05-03
4569 Mechano-metabolism of adherent cells in 2D and 3D microenvironments
Jaganathan, A.; Toth, J. M.; Chen, X.; Pieuchot, L.; Shen, Y.; Reinhart-King, C. A.; Shenoy, V. B.
10.1101/2024.04.30.591879 — biophysics — Posted on 2024-05-03
4570 Partial Fitch Graphs: Characterization, Satisfiability and Complexity
Korchmaros, A.; Hellmuth, M.; Ramirez-Rafael, J. A.; Schmidt, B.; Stadler, P. F.; Thekkumpadan Puthiyaveedu, S.
10.1101/2024.04.30.591842 — bioinformatics — Posted on 2024-05-03
4571 MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann, J. K. S.; Szczuka, M.; Bouarroudj, L.; Oussaren, M.; Garcia, S.; Howard, R. J.; Delemotte, L.; Lindahl, E.; Baaden, M.; Lindorff-Larsen, K.; Chavent, M.; Poulain, P.
10.1101/2023.05.02.538537 — bioinformatics — Posted on 2024-05-03
4574 Increased host diversity limits bacterial generalism but may promote microbe-microbe interactions
Holmes, I. A.; Martinez-Fonseca, J. G.; von May, R.; Sealey, B. A.; Cerda, P.; Grundler, M. R.; Westeen, E. P.; Nondorf, D.; Larson, J. G.; Myers, C. R.; Hendry, T. A.
10.1101/2024.04.24.590977 — ecology — Posted on 2024-05-03
4575 Biodiversity increases the forecastability of species abundances in changing environments
Limberger, R.; Daugaard, U.; Choffat, Y.; Gupta, A.; Jelic, M.; Jyrkinen, S.; Krug, R. M.; Nohl, S.; Pennekamp, F.; van Moorsel, S. J.; Zheng, X.; Zuppinger-Dingley, D.; Petchey, O. L.
10.1101/2024.04.30.591860 — ecology — Posted on 2024-05-03
4576 Local and global density have distinct and parasite-dependent effects on infection in wild sheep
Albery, G. F.; Sweeny, A. R.; Corripio-Miyar, Y.; Evans, M. J.; Hayward, A.; Pemberton, J. M.; Pilkington, J. G.; Nussey, D. H.
10.1101/2024.04.30.591781 — ecology — Posted on 2024-05-03
4578 Super homotypic targeting by exosome surface engineering
Wang, H.-S.; Ding, T.; Liu, Y.; Zhou, Y.; Zhao, Y.; Hayashi, M.; Hu, X.-Y.; Yang, Z.-W.; Ishii, N.; Matsumura, H.; Umirbaeva, A.; Guo, H.; Su, J.-L.; Yan, Y.-Y.; Gao, F.-H.; Li, J.-J.; Nitta, N.; Nishikawa, M.; Yatomi, Y.; Ding, Y.; Sonoshita, M.; Di Carlo, D.; Suetsugu, S.; Goda, K.
10.1101/2024.05.01.592036 — cell biology — Posted on 2024-05-03
4579 Mechanisms of cilia regeneration in Xenopus multiciliated epithelium in vivo.
Rao, V. G.; Subramanianbalachandar, V.; Magaj, M. M.; Redemann, S.; Kulkarni, S. S.
10.1101/2023.06.14.544972 — cell biology — Posted on 2024-05-03
4580 Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2
Goradia, N.; Werner, S.; Mullapudi, E.; Greimeier, S.; Merkens, L.; Lang, A.; Mertens, H. D. T.; Weglarz, A.; Sander, S.; Chojnowski, G.; Wikman, H.; Ohlenschlaeger, O.; von Amsberg, G.; Pantel, K.; Wilmanns, M.
10.1101/2023.06.16.545227 — molecular biology — Posted on 2024-05-03
4582 Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling
Farkas, A. M.; Tran, M. A.; Youssef, D.; Balan, S.; Newman, J. H.; Audenet, F.; Anastos, H.; Peros, A.; Ananthanarayanan, A.; Daza, J.; Gonzalez-Gugel, E.; Sadanala, K.; Theorell, J.; Galsky, M. D.; Horowitz, A.; Sfakianos, J. P.; Bhardwaj, N.
10.1101/2024.04.30.591366 — immunology — Posted on 2024-05-03
4585 Adapting C4 photosynthesis to atmospheric change and increasing productivity by elevating Rubisco content in Sorghum and Sugarcane
Salesse-Smith, C. E.; Adar, N.; Kannan, B.; Nguyen, T.; Guo, M.; Ge, Z.; Altpeter, F.; Clemente, T. E.; Long, S. P.
10.1101/2024.05.02.592081 — plant biology — Posted on 2024-05-03
4586 Phylogenomics reveals the evolutionary origin of lichenization in chlorophyte algae
Puginier, C.; Libourel, C.; Otte, J.; Skaloud, P.; Haon, M.; Grisel, S.; Petersen, M.; Berrin, J.-G.; Delaux, P.-M.; Dal Grande, F.; Keller, J.
10.1101/2022.01.06.475074 — plant biology — Posted on 2024-05-03
4589 Transient hypoxia followed by progressive reoxygenation is required for efficient skeletal muscle repair through Rev-ERBalpha modulation
QUETIN, M.; DUBOIS, C.; BERTHIER, J.; LEDOUX, M.; MICHINEAU, S.; DRAYTON-LIBOTTE, B.; Sotiropoulos, A.; Relaix, F.; Gervais, M.
10.1101/2024.05.02.592180 — physiology — Posted on 2024-05-03
4591 S100A9 Inhibits and Redirects Prion Protein 89-230 Fragment Amyloid Aggregation
Ziaunys, M.; Sulskis, D.; Mikalauskaite, K.; Sakalauskas, A.; Snieckute, R.; Smirnovas, V.
10.1101/2024.02.06.579161 — biochemistry — Posted on 2024-05-03
4594 Neurocognitive Mechanism of Radiologists Perceptual Errors: Results of Preliminary Studies
Bruno, M. A.; Krupinski, E. A.; Bunce, S. C.; Baird, G.; Mills, C.; Karunanayaka, P.; Egeth, H.; Chang, R.; Cottrill, R.; Jump, S.; Sathian, K.; Mosher, T. J.
10.1101/2024.04.29.591746 — neuroscience — Posted on 2024-05-03
4595 Sox5 controls the establishment of quiescence in neural stem cells during postnatal development
Medina-Menendez, C.; Li, L.; Tirado-Melendro, P.; Rodriguez-Martin, P.; Melgarejo-de la Pena, E.; Diaz-Garcia, M.; Valdes-Bescos, M.; Lopez-Sansegundo, R.; Morales, A. V.
10.1101/2024.05.03.592315 — developmental biology — Posted on 2024-05-03
4598 Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice
Lavigna, G.; Grasso, A.; Pasini, C.; Grande, V.; Mignogna, L.; Restelli, E.; Masone, A.; Fracasso, C.; Lucchetti, J.; Gobbi, M.; Chiesa, R.
10.1101/2024.04.30.591862 — pharmacology and toxicology — Posted on 2024-05-03
4600 The genetic architecture and evolutionary consequences of the human pelvic form
Xu, L.; Kun, E.; Pandey, D.; Wang, J.; Brasil, M.; Singh, T.; Narasimhan, V. M.
10.1101/2024.05.02.592256 — genetics — Posted on 2024-05-03
4601 Coleoid Cephalopods Demonstrate Asocial Path to the Evolution of Big Brains
Basava, K.; Bendixen, T.; Leonhard, A.; George, N. L.; Vanhersecke, Z.; Omotosho, J.; Mather, J.; Muthukrishna, M.
10.1101/2024.05.01.592020 — evolutionary biology — Posted on 2024-05-03
4602 Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity
Krause, C.; Britsemmer, J. H.; Bernecker, M.; Molenaar, A.; Taege, N.; Lopez Alcantara, N.; Geissler, C.; Kaehler, M.; Iben, K.; Judycka, A.; Wagner, J.; Wolter, S.; Mann, O.; Pfluger, P.; Cascorbi, I.; Lehnert, H.; Stemmer, K.; Schriever, S. C.; Kirchner, H.
10.1101/2023.10.02.560594 — molecular biology — Posted on 2024-05-03
4603 A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to copper stress
Leprevost, L.; Junger, S.; Lippens, G.; Guillaume, C.; Sicoli, G.; Oliveira Correia, L.; Rivera-Millot, A.; Billon, G.; Henry, C.; Antoine, R.; Zirah, S.; Dubiley, S.; Li, Y.; Jacob-Dubuisson, F.
10.1101/2024.03.18.585515 — microbiology — Posted on 2024-05-03
4604 MiDAS 5: Global diversity of bacteria and archaea in anaerobic digesters
Dueholm, M. K. D.; Andersen, K. S.; Petersen, A.-K. C.; Rudkjoebing, V.; Alves, M.; Bajon-Fernandez, Y.; Batstone, D.; Butler, C.; Cruz, M. C.; Davidsson, A.; Erijman, L.; Holliger, C.; Koch, K.; Kreuzinger, N.; Lee, C.; Lyberatos, G.; Mutnuri, S.; O'Flaherty, V.; Oleskowicz-Popiel, P.; Pokorna, D.; Rajal, V. B.; Recktenwald, M.; Rodriguez, J.; Saikaly, P. E.; Tooker, N.; Vierheilig, J.; De Vrieze, J.; Wurzbacher, C.; Nielsen, P. H.
10.1101/2023.08.24.554448 — microbiology — Posted on 2024-05-03
4605 SYNAPTIC PLASTICITY IN THE INJURED BRAIN DEPENDS ON THE TEMPORAL PATTERN OF STIMULATION
Fischer, Q. S.; Kalikulov, D.; Viana Di Prisco, G.; Williams, C. A.; Baldwin, P. R.; Friedlander, M. J.
10.1101/2023.12.13.571587 — neuroscience — Posted on 2024-05-03
4607 Evolutionary convergence of sensory circuits in the pallium of amniotes
Rueda-Alana, E.; Senovilla-Ganzo, R.; Grillo, M.; Vazquez, E.; Gallego-Flores, T.; Marco-Salas, S.; Ftara, A.; Escobar, L.; Benguria, A.; Quintas-Gorozarri, A.; Dopazo, A.; Rabano, M.; dM Vivanco, M.; Aransay, A. M.; Garrigos, D.; Toval, A.; Ferran, J. L.; Nilsson, M.; Encinas, J. M.; de Pitta, M.; Garcia-Moreno, F.
10.1101/2024.04.30.591819 — developmental biology — Posted on 2024-05-03
4608 Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infections
Lasaviciute, G.; Tariq, K.; Sugathan, A.; Quin, J. E.; Bujila, I.; Skorokhod, O.; Troye-Blomberg, M.; Sverremark-Ekstrom, E.; Ostlund Farrants, A.-K.
10.1101/2024.03.18.585548 — cell biology — Posted on 2024-05-03
4609 Aversive memories can be weakened during human sleepvia the reactivation of positive interfering memories
Xia, T.; Chen, D.; Zeng, S.; Yao, Z.; Liu, J.; Qin, S.; Paller, K. A.; Torres-Platas, S. G.; Antony, J. W.; Hu, X.
10.1101/2023.12.05.570072 — neuroscience — Posted on 2024-05-03
4611 Optogenetic stimulation recruits cortical neurons in amorphology-dependent manner
Berling, D.; Baroni, L.; Chaffiol, A.; Gauvain, G.; Picaud, S.; Antolik, J.
10.1101/2024.03.18.585466 — neuroscience — Posted on 2024-05-03
4612 HSP90 inhibitor NVP-HSP990 alleviates rotavirus infection
Cao, Y.; Zhu, Q.; Wu, X.; Xie, Z.; Yang, C.; Guo, Y.; Meng, D.; Zhou, X.; Wu, Y.; Li, J.; He, h.
10.1101/2023.06.15.545197 — microbiology — Posted on 2024-05-03
4616 Glutathione supersulphide regulates T-cell receptor signalling
Sasaki, Y.; Numakura, T.; Yamada, M.; Sugiura, H.; Matsunaga, T.; Ida, T.; Morita, M.; Suzuki, A.; Matsumoto, S.; Kawaguchi, M.; Kawabe, T.; Tayama, S.; Okuyama, Y.; Takata, T.; Inaba, K.; Watanabe, S.; Suzuki, M.; Sano, H.; Kyogoku, Y.; Tanaka, R.; Mitsune, A.; Ichikawa, T.; Fujino, N.; Tamada, T.; Ishii, N.; Ichinose, M.; Akaike, T.; Motohashi, H.
10.1101/2024.04.30.591985 — biochemistry — Posted on 2024-05-02
4617 Design of High Affinity Binders to Convex Protein Target Sites
Baker, D.; Yang, W.; Hicks, D. R.; Ghosh, A.; Schwartze, T. A.; Coventry, B.; Goreshnik, I.; Allen, A.; Halabiya, S.; Kim, C.; Hinck, C. S.; Lee, D. S.; Bera, A.; Li, Z.; Wang, Y.; Schlichthaerle, T.; Cao, L.; Huang, B.; Garrett, S.; Gerben, S. R.; Rettie, S.; Heine, P.; Edman, N.; Murray, A. N.; Carter, L. P.; Stewart, L.; Almo, S.; Hinck, A. P.
10.1101/2024.05.01.592114 — biochemistry — Posted on 2024-05-03
4619 Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection
Ke, S.; Villafuerte Galvez, J. A.; Sun, Z.; Cao, Y.; Pollock, N. R.; Chen, X.; Kelly, C. P.; Liu, Y.-Y.
10.1101/2024.04.30.591969 — microbiology — Posted on 2024-05-02
4621 Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs
Manning, A. C.; Bashir, M. M.; Jimenez, A. R.; Upton, H.; Collins, K.; Lowe, T. M.; Tucker, J. M.
10.1101/2024.05.01.592122 — microbiology — Posted on 2024-05-02
4622 IL-2 enhances effector function but suppresses follicular localization of CD8+ T cells in chronic infection
Chen, Y.; Zhou, P.; Gubser, P. M.; Leong, Y. A.; He, J.; Wei, Y.; Makota, F. V.; Pazhouhandeh, M.; Zheng, T.; Yunis, J.; Li, Z.; Kallies, A.; Yu, D.
10.1101/2024.05.02.592184 — immunology — Posted on 2024-05-02
4624 Tipping point in α-synuclein-membrane interactions: stable protein-covered vesicles or amyloid aggregation
Makasewicz, K.; Carlström, G.; Stenström, O.; Bernfur, K.; Fridolf, S.; Akke, M.; Linse, S.; Sparr, E.
10.1101/2024.05.01.592005 — biochemistry — Posted on 2024-05-02
4626 Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in 40S small ribosomal subunit
Brito Querido, J.; Sokabe, M.; Diaz-Lopez, I.; Gordiyenko, Y.; Zuber, P.; Du, Y.; Albacete-Albacete, L.; Ramakrishnan, V.; Fraser, C. S.
10.1101/2024.05.01.592117 — biochemistry — Posted on 2024-05-02
4630 Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease
Katta, V.; O'Keefe, K.; Li, Y.; Mayuranathan, T.; Levine, R. M.; Lazzarotto, C. R.; Wood, R. K.; Powers, A.; Mayberry, K.; Manquen, G.; Yao, Y.; Zhang, J.; Jang, Y.; Nimmagadda, N.; Dempsey, E. A.; Lee, G.; Uchida, N.; Cheng, Y.; Fazio, F.; Lockey, T.; Meagher, M.; Sharma, A.; Tisdale, J. F.; Zhou, S.; Yen, J. S.; Weiss, M. J.; Tsai, S. Q.
10.1101/2024.04.30.591737 — genomics — Posted on 2024-05-02
4631 Insights into the representativeness of biodiversity assessment in large reservoir through eDNA metabarcoding
Cortez, T.; Torres, A. L.; Guimaraes, M.; Pinheiro, H. B.; Cabral, M.; Zielinsky, G.; Pereira, C. M.; de Castro, G. M.; Guerreiro, L. T.; Americo, J. A.; do Amaral, D. L.; Rebelo, M. F.
10.1101/2024.05.02.592166 — molecular biology — Posted on 2024-05-02
4632 Cobalt effects on prokaryotic communities living in growing river biofilms: impact on their colonization kinetics, structure and functions.
Gourgues, S.; Goni-Urriza, M.; Milhe-Poutingon, M.; Baldoni-Andrey, P.; Gurrief, N. B.; Gelber, C.; Le Faucheur, S.
10.1101/2024.05.02.592147 — molecular biology — Posted on 2024-05-02
4633 A germline PAF1 paralog complex ensures cell type-specific gene expression
Vilstrup, A. P.; Gupta, A.; Rasmussen, A. J.; Ebert, A.; Riedelbauch, S.; Lukassen, M. V.; Hayashi, R.; Andersen, P.
10.1101/2024.05.02.592153 — molecular biology — Posted on 2024-05-02
4634 CetZ1-dependent assembly and positioning of the motility machinery in haloarchaea
Brown, H. J.; Islam, M. I.; Ruan, J.; Baker, M. A.; Ithurbide, S.; Duggin, I. G.
10.1101/2024.05.02.592137 — microbiology — Posted on 2024-05-02
4638 Quantification of influenza virus mini viral RNA dynamics using Cas13
Lamb, C.; Pitre, E.; Elshina, E.; Rigby, C.; Bisht, K.; Oade, M. S.; Jalal, H.; Myhrvold, C.; te Velthuis, A. J. W.
10.1101/2023.11.03.565460 — microbiology — Posted on 2024-05-02
4639 A Kv2 inhibitor combination reveals native neuronal conductances consistent with KvS heteromers.
Stewart, R. G.; Marquis, M. J.; Jo, S.; Ferns, M.; Sack, J. T.; Aberra, A.; Cook, V.; Whiddon, Z.
10.1101/2024.01.31.578214 — neuroscience — Posted on 2024-05-02
4640 Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains
Mancinelli, C.; Marx, D. C.; Gonzalez-Hernandez, A. J.; Huynh, K.; Mancinelli, L.; Arefin, A.; Khelashvili, G.; Levitz, J.; Eliezer, D.
10.1101/2023.08.16.553551 — biophysics — Posted on 2024-05-02
4642 Identifying Naturalistic Movies from Human Brain Activity with High-Density Diffuse Optical Tomography
Markow, Z. E.; Tripathy, K.; Svoboda, A. M.; Schroeder, M. L.; Rafferty, S. M.; Richter, E. J.; Eggebrecht, A. T.; Anastasio, M. A.; Chevillet, M. A.; Mugler, E. M.; Naufel, S. N.; Yin, A.; Trobaugh, J. W.; Culver, J. P.
10.1101/2023.11.27.566650 — bioengineering — Posted on 2024-05-02
4644 A novel VCP modulator, KUS121, attenuates atherosclerosis progression by maintaining intracellular ATP and mitigating ER stress in endothelial cells
Baba, O.; Zou, F.; Horie, T.; Nakashima, Y.; Tsuji, S.; Yamasaki, T.; Otani, C.; Xu, S.; Imanaka, M.; Matsushita, K.; Suzuki, K.; Kume, E.; Kojima, H.; Qian, Q.; Kimura, K.; Sowa, N.; Kakizuka, A.; Ono, K.
10.1101/2024.04.29.591786 — pathology — Posted on 2024-05-02
4652 Downregulation of PIK3IP1/TrIP on T cells is controlled by TCR signal strength, PKC, and metalloprotease-mediated cleavage
Murter, B. M.; Robinson, S. C.; Banerjee, H.; Lau, L.; Uche, U.; Szymczak-Workman, A. L.; Kane, L. P.
10.1101/2024.04.29.591680 — cell biology — Posted on 2024-05-02
4653 Non-invasive evidence for rhythmic interactions between the human brain, spinal cord, and muscle
Spedden, M. E.; O'Neill, G. C.; Timms, R. C.; West, T. O.; Mellor, S. J.; Tierney, T. M.; Alexander, N. A.; Seymour, R.; Farmer, S. F.; Bestmann, S.; Barnes, G. R.
10.1101/2024.05.01.591590 — neuroscience — Posted on 2024-05-02
4655 3-Nitropropionic acid induces histological and behavioral alterations in adult zebrafish: role of antioxidants on behavioral dysfunction
Wiprich, M. T.; Vasques, R. d. R.; Zaluski, A. B.; Bertoncello, K.; Altenhofen, S.; Gusso, D.; Rodrigues, G.; Sachett, A.; Piato, A.; Maito, F. L. D. M.; Vianna, M. R. M.; Bonan, C. D.
10.1101/2024.04.29.591507 — pharmacology and toxicology — Posted on 2024-05-02
4657 Deep Quantitative Proteomics Identifies Conserved Proteome Alterations in Low and High-Grade Serous Ovarian Cancers
Tarney, C. M.; Mhawech-Fauceglia, P.; Ogata, J.; Oliver, J.; Abulez, T.; Hood, B. L.; Conrads, K. A.; Rosalik, K.; Wong, K.-K.; Gershenson, D. M.; Lee, S.; Sood, A. K.; Bast, R. C.; Darcy, K. M.; Phippen, N. T.; Maxwell, G. L.; Conrads, T. P.; Bateman, N. W.
10.1101/2024.04.29.591278 — cancer biology — Posted on 2024-05-02
4667 ChatNT: A Multimodal Conversational Agent for DNA, RNA and Protein Tasks
Richard, G.; de Almeida, B. P.; Dalla-Torre, H.; Blum, C.; Hexemer, L.; Pandey, P.; Laurent, S.; Lopez, M. P.; Laterre, A.; Lang, M.; Sahin, U.; Beguir, K.; Pierrot, T.
10.1101/2024.04.30.591835 — genomics — Posted on 2024-05-02
4669 MASTR-seq: Multiplexed Analysis of Short Tandem Repeats with sequencing
Chandradoss, K. R.; Su, C.; Malachowski, T.; Boya, R.; Ryu, H.-S.; Brennand, K.; Phillips-Cremins, J. E.
10.1101/2024.04.29.591790 — genomics — Posted on 2024-05-02
4670 Revealing the evolutionary history and contemporary population structure of Pacific salmon in the Fraser River through genome resequencing
Christensen, K. A.; Flores, A.-M.; Sakhrani, D.; Biagi, C. A.; Devlin, R. H.; Sutherland, B. J. G.; Withler, R. E.; Rondeau, E. B.; Koop, B. F.
10.1101/2024.04.29.591761 — evolutionary biology — Posted on 2024-05-02
4673 Spleen gene expression is associated with mercury content in three-spined stickleback populations
Yadav, B. S.; Lamaze, F. C.; Shankregowda, A. M.; Delahaut, V.; Calboli, F. C. F.; Patel, D. M.; Kuizenga, M.; Bervoets, L.; Volckaert, F. A. M.; Boeck, G. D.; Raeymaekers, J. A. M.
10.1101/2024.04.29.591498 — ecology — Posted on 2024-05-02
4676 The embryo-derived protein PDI is highly conserved among placental mammals and alters the function of the endometrium in species with different implantation strategies.
Tinning, H.; Taylor, A.; Wang, D.; Pullinger, A.; Oikonomou, G.; Velazquez, M. A.; Thompson, P.; Treumann, A.; Ruane, P. T.; O'Connell, M. J.; Forde, N.
10.1101/2024.05.02.592140 — developmental biology — Posted on 2024-05-02
4682 Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory
Watson, J. F.; Vargas-Barroso, V.; Morse-Mora, R. J.; Navas-Olive, A.; Tavakoli, M. R.; Danzl, J. G.; Tomschik, M.; Rössler, K.; Jonas, P.
10.1101/2024.05.02.592169 — neuroscience — Posted on 2024-05-02
4684 Impact of PIK3CA gain and PTEN loss on mantle cell lymphoma biology and sensitivity to targeted therapies
Bettazova, N.; Senavova, J.; Kupcova, K.; Sovilj, D.; Rajmonova, A.; Andera, L.; Svobodova, K.; Berkova, A.; Herman, V.; Zemanova, Z.; Daumova, L.; Dolnikova, A.; Davis, R. E.; Trneny, M.; Klener, P.; Havranek, O.
10.1101/2024.04.30.591749 — cancer biology — Posted on 2024-05-02
4686 A high-quality de novo genome assembly of Asian Crested Ibis (Nipponia Nippon) using long-read and Hi-C data
yu, y.; Kim, S.-j.; Yoon, C.; Bhak, J.; Kim, C.; Park, H.; Kang, Y.; Kim, Y.; Lee, Y.-j.; Kang, S.-y.; Shin, Y.-u.; Bhak, J.; Jeon, S.
10.1101/2024.04.29.591545 — bioinformatics — Posted on 2024-05-02
4689 Reproducible differentiation of pure ovarian support cells from clinical-grade hiPSCs as a novel infertility treatment
Paulsen, B.; Barrachina, F.; Noblett, A. D.; Johnson, M.; Kats, S.; Piechota, S.; Marchante, M.; Figueroa, A. B.; Potts, K. S.; Rockwell, G.; Giovannini, A.; Kramme, C. C.
10.1101/2024.04.29.591741 — bioengineering — Posted on 2024-05-02
4691 Modulation of calcium signaling on demand to decipher the molecular mechanisms of primary aldosteronism
Fedlaoui, B.; Cosentino, T.; Al Sayed, Z. R.; Giscos-Douriez, I.; Faedda, N.; Fayad, M.; Hulot, J.-S.; Magnus, C.; Sternson, S. M.; Travers-Allard, S.; Baron, S.; Fernandes-Rosa, F. L.; Zennaro, M.-C.; Boulkroun, S.
10.1101/2024.04.29.591306 — physiology — Posted on 2024-05-02
4694 Human ESCRT-I and ALIX function as scaffolding helical filaments in vivo
Spada, S. J.; Rose, K. M.; Sette, P.; O'Connor, S. K.; Dussupt, V. B.; Yerramilli, V. S.; Nagashima, K.; Helle Sjoelund, V.; Cruz, P.; Kabat, J.; Smelkinson, M.; Ganesan, S.; Nita-Lazar, A.; Scarlata, S.; Hirsch, V.; Best, S.; Grigg, M. E.; Bouamr, F.
10.1101/2024.05.01.592080 — cell biology — Posted on 2024-05-02
4695 The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity
Kalkreuter, E.; Kautsar, S. A.; Yang, D.; Teijaro, C. N.; Bader, C. D.; Fluegel, L. L.; Davis, C. M.; Simpson, J. R.; Steele, A. D.; Gui, C.; Meng, S.; Li, G.; Viehrig, K.; Ye, F.; Su, P.; Kiefer, A. F.; Lauterbach, L.; Nichols, A.; Cepeda, A. J.; Yan, W.; Fan, B.; Jiang, Y.; Adhikari, A.; Zheng, C.-J.; Schuster, L.; Cowan, T. M.; Smanski, M.; Chevrette, M. G.; de Carvalho, L. P. S.; Shen, B.
10.1101/2023.12.14.571759 — microbiology — Posted on 2024-05-02
4696 Behavioral screening of conserved RNA-binding proteins reveals CEY-1/YBX RNA-binding protein dysfunction leads to impairments in memory and cognition
Hayden, A. N.; Brandel, K. L.; Merlau, P. R.; Vijayakumar, P.; Leptich, E. J.; Pietryk, E. W.; Gaytan, E. S.; Ni, C. W.; Chao, H.-T.; Rosenfeld, J. A.; Arey, R. N.
10.1101/2024.01.05.574402 — neuroscience — Posted on 2024-05-02
4698 Aberrant cytoplasmic localization of MLH1 characterizes a sub-clonal breast cancer cell population that seeds recurrence
Mazumder, A.; DeWitt, T.; Oropeza, E.; Punturi, N.; Lozano, D.; Sajjadi, E.; Guerini-Rocco, E.; Venetis, K.; Ivanova, M.; Mane, E.; Fusco, N.; Haricharan, S.
10.1101/2024.02.27.582389 — cancer biology — Posted on 2024-05-02
4704 A highly resolved network reveals the role of terrestrial herbivory in structuring aboveground food webs
Hale, K. R. S.; Curlis, J. D.; Auteri, G. G.; Bishop, S.; French, R. L. K.; Jones, L. E.; Mills, K. L.; Simons, M.; Scholtens, B. G.; Thompson, C.; Tourville, J.; Valdovinos, F. S.
10.1101/2023.10.05.560934 — ecology — Posted on 2024-05-02
4705 Airway injury induces alveolar epithelial and mesenchymal responses mediated by macrophages
Wong, I. G.; Stark, J.; Ya, V.; Moye, A. L.; Vazquez, A. B.; Dang, S. M.; Shehaj, A.; Rouhani, M. J.; Bronson, R.; Janes, S. M.; Rowbotham, S. P.; Paschini, M.; Franklin, R. A.; Kim, C. F.
10.1101/2024.04.02.587596 — cell biology — Posted on 2024-05-02
4706 Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells
Long, Y.; Hwang, T.; Gooding, A. R.; Goodrich, K. J.; Vallery, T. K.; Rinn, J. L.; Hanson, S. D.; Cech, T. R.
10.1101/2023.08.17.553776 — molecular biology — Posted on 2024-05-02
4707 Non-canonical activation of IRE1a during Candida albicans infection enhances macrophage fungicidal activity
McFadden, M. J.; Reynolds, M. B.; Michmerhuizen, B. C.; Olafsson, E. B.; Anderson, F. M.; Schultz, T. L.; O'Riordan, M. X. D.; O'Meara, T. R.
10.1101/2023.10.02.560560 — molecular biology — Posted on 2024-05-02
4708 A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula
Vidal-Vazquez, N.; Hernandez-Nunez, I.; Carballo-Pacoret, P.; Salisbury, S.; Villamayor, P. R.; Hervas-Sotomayor, F.; Yuan, X.; Lamanna, F.; Schneider, C.; Schmidt, J.; Mazan, S.; Kaessmann, H.; Adrio, F.; Robledo, D.; Barreiro-Iglesias, A.; Candal, E.
10.1101/2024.04.12.589211 — neuroscience — Posted on 2024-05-02
4711 DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment
Hwang, R.-D.; Lu, Y.; Tang, Q.; Periz, G.; Park, G.; Li, X.; Xiang, Q.; Liu, Y.; Zhang, T.; Wang, J.
10.1101/2023.09.12.556394 — neuroscience — Posted on 2024-05-02
4713 Beta-aminopropionitrile Induces Distinct Pathologies in the Ascending and Descending Thoracic Aortic Regions of Young Mice
Franklin, M. K.; Sawada, H.; Howatt, D. A.; Amioka, N.; Liang, C.-L.; Zhang, N.; Graf, D. B.; Moorleghen, J. J.; Katsumata, Y.; Lu, H. S.; Daugherty, A.
10.1101/2023.10.22.563474 — pathology — Posted on 2024-05-02
4716 Transcriptional remodeling of the Stromal and Endothelial Microenvironment in MGUS to Multiple Myeloma Progression
Cenzano, I.; Cocera, M.; Bantan, A.; Larrayoz, M.; Vilas, A.; San-Martin, P.; Aguirre-Ruiz, P.; Alignani, D.; Lopez, A.; Minana, M.; Quilez Agreda, D.; Sancho Gonzalez, I.; Ruiz, J.; Lagani, V.; Tegner, J.; Martin-Subero, I.; Agirre, X.; Paiva, B.; Rodriguez-Otero, P.; Tamariz-Amador, L.-E.; San-Miguel, J.; Martinez-Climent, J. A.; Saez, B.; Hernaez, M.; Calvo, I. A.; Gomez-Cabrero, D.; Prosper, F.
10.1101/2024.04.24.589777 — cancer biology — Posted on 2024-05-02
4717 Identification and validation of drugs for repositioning in Glioblastoma: a computational and experimental workflow
Gonzalez, N.; Perez Kuper, M.; Garcia Fallit, M.; Pena Agudelo, J.; Nicola Candia, A.; Suarez Velandia, M.; Videla-Richardson, G.; Candolfi, M.
10.1101/2024.04.29.589520 — cancer biology — Posted on 2024-05-02
4720 Biocompatibility of KAPs-Depleted Residual Hair
Meer, A.; Mathews, A.; Cabral, M.; Tarabokija, A.; Carroll, E.; Chaudhry, H.; Paszek, M.; Radecker, N.; Palaia, T.; de Guzman, R. C.
10.1101/2024.04.29.591537 — bioengineering — Posted on 2024-05-02
4723 Emergent Ecological Patterns and Modelling of Gut Microbiomes in Health and in Disease
Pasqualini, J.; Facchin, S.; Rinaldo, A.; Maritan, A.; Savarino, E.; Suweis, S.
10.1101/2023.10.19.563037 — ecology — Posted on 2024-05-02
4724 Assembly processes inferred from eDNA surveys of a pond metacommunity are consistent with known species ecologies
Cai, W.; Pichler, M.; Biggs, J.; Nicolet, P.; Ewald, N.; Griffiths, R. A.; Bush, A.; Leibold, M. A.; Hartig, F.; Yu, D. W.
10.1101/2023.12.12.571176 — ecology — Posted on 2024-05-02
4725 Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey
Sidous, M.; Cubaynes, S.; Gimenez, O.; Drouet-Hoguet, N.; Dray, S.; Bollache, L.; Madhlamoto, D.; Ngwenya, N. A.; Fritz, H.; Valeix, M.
10.1101/2023.11.08.566247 — ecology — Posted on 2024-05-02
4726 Multi-SpinX: An Advanced Framework for Automated Tracking of Mitotic Spindles and Kinetochores in Multicellular Environments
Chai, B.; Efstathiou, C.; Choudhury, M.; Kuniyasu, K.; Jain, S. S.; Maharea, A.-C.; Tanaka, K.; Draviam, V. M.
10.1101/2024.04.03.587736 — cell biology — Posted on 2024-05-02
4727 Allergic inflammation triggers dyslipidemia via IgG signalling
Fernandez-Gallego, N.; Castillo-Gonzalez, R.; Moreno-Serna, L.; Garcia-Civico, A. J.; Sanchez-Martinez, E.; Lopez-Sanz, C.; Fontes, A. L.; Pimentel, L. L.; Gradillas, A.; Obeso, D.; Neuhaus, R.; Ramirez-Huesca, M.; Ruiz-Fernandez, I.; Nunez-Borque, E.; Carrasco, Y. R.; Ibanez, B.; Martin, P.; Blanco, C.; Barbas, C.; Barber, D.; Rodriguez-Alcala, L. M.; Villasenor, A.; Esteban, V.; Sanchez-Madrid, F.; Jimenez-Saiz, R.
10.1101/2023.08.04.551996 — immunology — Posted on 2024-05-02
4728 The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner
Wallings, R.; McFarland, K.; Staley, H.; Neighbarger, N.; Schaake, S.; Brueggemann, N.; Zittel, S.; Usnich, T.; Klein, C.; Sammler, E.; Tansey, M. G.
10.1101/2023.10.12.562063 — immunology — Posted on 2024-05-02
4729 Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
Francavilla, R.; Chattopadhyaya, B.; Damo Kamda, J. L.; Jadhav, V.; Kourrich, S.; Michaud, J. L.; Di Cristo, G.
10.1101/2024.02.27.582362 — neuroscience — Posted on 2024-05-02
4733 Concepts and methods for predicting viral evolution
Meijers, M.; Ruchnewitz, D.; Eberhardt, J.; Karmakar, M.; Łuksza, M.; Lässig, M.
10.1101/2024.03.19.585703 — biophysics — Posted on 2024-05-02
4735 miRNA-29-CLIP uncovers new targets and functions to improve skin repair
Thiagarajan, L.; Sanchez-Alvarez, R.; Kambara, C.; Rajasekar, P.; Wang, Y.; Halloy, F.; Hall, J.; Stark, H.-J.; Martin, I.; Boukamp, P.; Kurinna, S.
10.1101/2024.05.02.591622 — cell biology — Posted on 2024-05-02
4736 AHR activation accelerates the resolution of TGF-β1 induced fibroblast activation and promotes alveolar type 1 cell regeneration in alveolar organoids
Hagan, A. S.; Williams, S.; Mathison, C. J. N.; Yan, S.; Nguyen, B.; Federe, G. C.; Kuzu, G.; Siefert, J. C.; Hampton, J.; Chichkov, V.; Barnes, S. W.; King, F. J.; Taylor, B.; Walker, J. R.; Zhao, R.; Elliott, J.; Phillips, D. P.; Fang, B.; Decker, R. S.
10.1101/2024.04.29.590972 — cell biology — Posted on 2024-05-02
4741 WITHDRAWN: Exposure to an enriched environment improves colonic epithelial barrier integrity and attenuates mouse experimental colitis by modulating a Myc-driven gene regulatory network
Villa-Senor-Toledo, T.; Valle-Garcia, D.; Pop, R. T.; Osio-Becerro, V.; Meza-Sosa, K. F.; Serrano, C.; Diaz de Leon-Guerrero, S.; Hernandez-Pando, R.; Nava, P.; Kuijjer, M. L.; Perez-Martinez, L.; Pedraza-Alva, G.
10.1101/2023.02.16.528051 — immunology — Posted on 2024-05-02
4745 Sodium-glucose co-transporter 2 Inhibitors Act Independently of SGLT2 to Confer Benefit for Heart Failure with Reduced Ejection Fraction in Mice
Berger, J. H.; Matsuura, T. R.; Bowman, C. E.; Taing, R.; Patel, J.; Lai, L.; Leone, T. C.; Reagan, J. D.; Haldar, S. M.; Arany, Z.; Kelly, D. P.
10.1101/2024.04.29.591665 — physiology — Posted on 2024-05-02
4750 Atomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates
Ahmed, R.; Liang, M.; Hudson, R. P.; Rangadurai, A. K.; Huang, S. K.; Forman-Kay, J. D.; Kay, L. E.
10.1101/2024.04.29.591724 — biophysics — Posted on 2024-05-02
4753 Atlas of imprinted and allele-specific DNA methylation in the human body
Rosenski, J.; Peretz, A.; Magenheim, J.; Loyfer, N.; Shemer, R.; Glaser, B.; Dor, Y.; Kaplan, T.
10.1101/2024.05.01.591988 — genomics — Posted on 2024-05-02
4756 Comparative single cell analysis reveals complex patterns of cell type and cell signaling innovations at the fetal-maternal interface
Stadtmauer, D. J.; Basanta, S.; Maziarz, J. D.; Cole, A. G.; Dagdas, G.; Smith, G. R.; van Breukelen, F.; Pavlicev, M.; Wagner, G. P.
10.1101/2024.05.01.591945 — evolutionary biology — Posted on 2024-05-02
4759 A prefrontal cortex-lateral hypothalamus circuit controls stress-driven food intake
Supiot, L. F.; Benschop, C.; Nicolson, S.; Haak, R.; Wolterink-Donselaar, I.; Luijendijk, M.; Adan, R.; Poorthuis, R.; Meye, F. J.
10.1101/2024.05.02.592146 — neuroscience — Posted on 2024-05-02
4761 An ultrasound-guided biopsy technique for obtaining supraclavicular brown fat biopsies and preadipocytes
Andersen, E. S.; Jespersen, N. Z.; Henriksen, T. I.; Pedersen, B. K.; Scheele, C.; Nielsen, M. B.; Nielsen, S.
10.1101/2024.04.30.570595 — physiology — Posted on 2024-05-02
4762 Dynamic mechanisms for membrane skeleton transitions
Bonilla-Quintana, M.; Ghisleni, A.; Gauthier, N. C.; Rangamani, P.
10.1101/2024.04.29.591779 — biophysics — Posted on 2024-05-02
4763 Amyloid Accelerator Polyphosphate Implicated as the Mystery Density in α-Synuclein Fibrils
Huettemann, P.; Mahadevan, P.; Lempart, J.; Tse, E.; Dehury, B.; Edwards, B. F.; Southworth, D. R.; Sahoo, B. R.; Jakob, U.
10.1101/2024.05.01.592011 — biophysics — Posted on 2024-05-02
4765 Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence
Perez, C. R.; Garmilla, A.; Nilsson, A.; Baghdassarian, H. M.; Gordon, K. S.; Lima, L. G.; Smith, B. E.; Maus, M. V.; Lauffenburger, D. A.; Birnbaum, M. E.
10.1101/2024.04.29.591541 — immunology — Posted on 2024-05-02
4766 Aberrant cytoplasmic localization of MLH1 characterizes a sub-clonal breast cancer cell population that seeds recurrence
Haricharan, S.; Mazumder, A.; DeWitt, T.; Oropeza, E.; Punturi, N.; Lozano, D.; Sajjadi, E.; Guerini-Rocco, E.; Venetis, K.; Ivanova, M.; Mane, E.; Fusco, N.
10.1101/2024.02.27.582389 — cancer biology — Posted on 2024-05-02
4768 Nanomotif: Identification and Exploitation of DNA Methylation Motifs in Metagenomes using Oxford Nanopore Sequencing
Heidelbach, S.; Dall, S. M.; Boejer, J. S.; Nissen, J.; van der Maas, L. N. L.; Sereika, M.; Kirkegaard, R.; Kousgaard, S. J.; Thorlacius-Ussing, O.; Jensen, S. I.; Hose, K.; Nielsen, T. D.; Albertsen, M.
10.1101/2024.04.29.591623 — bioinformatics — Posted on 2024-05-02
4770 Transcriptome-wide mRNA condensation precedes stress granule formation and excludes stress-induced transcripts
Glauninger, H.; Bard, J. A. M.; Wong Hickernell, C. J.; Airoldi, E. M.; Li, W.; Singer, R. H.; Paul, S.; Fei, J.; Sosnick, T. R.; Wallace, E. W. J.; Drummond, D. A.
10.1101/2024.04.15.589678 — cell biology — Posted on 2024-05-02
4771 PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis
Liu, G.; Hou, Y.; Jin, X.; Zhang, Y.; Sun, C.; Huang, C.; Ren, Y.; Gao, J.; Wang, X.; Jiang, X.
10.1101/2024.02.05.578960 — cell biology — Posted on 2024-05-02
4772 Autophagy is suppressed in peripheral blood mononuclear cells during chronic obstructive pulmonary disease.
Cooper, J.; Chen, S.; Lester, S. E.; Kim, J.; Gummow, J. A.; Crowhurst, T.; Lawton, E.; Badiei, A.; Nguyen, P. T.; Jersmann, H. P.; Roscioli, E.
10.1101/2024.04.27.591479 — molecular biology — Posted on 2024-05-02
4773 Aerobic Adaptation and Metabolic Dynamics of Propionibacterium freudenreichii DSM 20271: Insights from Comparative Transcriptomics and Surfaceome Analysis
Loivamaa, I.; Sillanpää, A.; Deptula, P.; Chamlagain, B.; Edelmann, M.; Auvinen, P.; Nyman, T. A.; Savijoki, K.; Piironen, V.; Varmanen, P.
10.1101/2024.04.30.591863 — microbiology — Posted on 2024-05-02
4775 Pixel-wise programmability enables dynamic high-SNR cameras for high-speed microscopy
Zhang, J.; Newman, J.; Wang, Z.; Qian, Y.; Feliciano-Ramos, P.; Guo, W.; Honda, T.; Chen, Z. S.; Linghu, C.; Etienne-Cummings, R.; Fossum, E.; Boyden, E.; Wilson, M. A.
10.1101/2023.06.27.546748 — neuroscience — Posted on 2024-05-02
4776 Generalization in motor learning: learning bimanual coordination with one hand
Wang, Y.; Weinrich, M. M.; Lei, Y.; Wright, D. L.; Sandhu, M.; Buchanan, J. J.; Kennedy, D. M.
10.1101/2024.04.29.591705 — neuroscience — Posted on 2024-05-02
4777 Nature exposure induces hypoalgesia by acting on nociception-related neural processing
Steininger, M. O.; White, M. P.; Lengersdorff, L.; Zhang, L.; Smalley, A. J.; Kuehn, S.; Lamm, C.
10.1101/2024.04.29.591600 — neuroscience — Posted on 2024-05-02
4782 AdjuSST: An Adjustable Surface Stiffness Treadmill
Price, M. A.; Locurto, D.; Abdikadirova, B.; Huber, M. E.; Hoogkamer, W.
10.1101/2024.03.25.586685 — bioengineering — Posted on 2024-05-02
4783 Ultra-deep proteomics by Thin-diaPASEF with a 60-cm long column system
Konno, R.; Ishikawa, M.; Nakajima, D.; Hagiwara, S.; Inukai, K.; Ohara, O.; Kawashima, Y.
10.1101/2024.04.26.591246 — biochemistry — Posted on 2024-05-02
4784 Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration
Surya, A.; Bolton, B. M.; Rothe, R.; Mejia-Trujillo, R.; Zhao, Q.; Leonita, A.; Liu, Y.; Rangan, R.; Gorusu, Y.; Nguyen, P.; Cenik, C.; Sarinay Cenik, E.
10.1101/2024.04.16.589775 — genetics — Posted on 2024-05-02
4787 Evolutionary convergence of sensory circuits in the pallium of amniotes
Rueda-Alana, E.; Senovilla-Ganzo, R.; Grillo, M.; Vazquez, E.; Gallego-Flores, T.; Marco-Salas, S.; Ftara, A.; Escobar, L.; Benguria, A.; Quintas-Gorozarri, A.; Dopazo, A.; Rabano, M.; dM Vivanco, M.; Aransay, A. M.; Garrigos, D.; Toval, A.; Ferran, J. L.; Nilsson, M.; Encinas, J. M.; de Pitta, M.; Garcia-Moreno, F.
10.1101/2024.04.30.591819 — developmental biology — Posted on 2024-05-02
4788 Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan.
Wimer, L.; Kaneshiro, K. R.; Ramirez, J.; Bose, N.; Contreras, M. V.; Shanmugam, M.; Gaffney, D.; Singh, P.; Beck, J.; Sellegounder, D.; Enriquez Najera, L.; Melov, S.; Ellerby, L.; Cho, S.-J.; Newman, J.; Galligan, J.; Koliwad, S.; Kapahi, P.
10.1101/2022.08.10.503411 — molecular biology — Posted on 2024-05-02
4789 Comparative reservoir competence of Peromyscus leucopus, C57BL/6J, and C3H/HeN for Borrelia burgdorferi B31
Bourgeois, J.; You, S. S.; Clendenen, L. H.; Shrestha, M.; Petnicki-Ocwieja, T.; Telford, S.; Hu, L.
10.1101/2023.09.28.559638 — microbiology — Posted on 2024-05-02
4791 A dual role for CRTH2 in acute lung injury
Bhattacharya, S.; Ristic, N.; Cohen, A. J.; Tsang, D.; Gwin, M.; Howell, R.; Young, G.; Jung, E.; Dela Cruz, C. S.; Gautam, S.
10.1101/2022.05.29.493897 — immunology — Posted on 2024-05-02
4792 Neurocognitive Mechanism of Radiologists Perceptual Errors: Results of Preliminary Studies
Bruno, M. A.; Krupinski, E. A.; Bunce, S. F.; Baird, G.; Mills, C.; Karunanayaka, P.; Egeth, H.; Chang, R.; Cottrill, R.; Jump, S.; Sathian, K.; Mosher, T. J.
10.1101/2024.04.29.591746 — neuroscience — Posted on 2024-05-02
4794 A deep learning and digital archaeology approach for mosquito repellent discovery
Wei, J. N.; Ruiz, C.; Vlot, M.; Sanchez-Lengeling, B.; Lee, B. K.; Berning, L.; Vos, M. W.; Henderson, R. W.; Qian, W. W.; Ando, D. M.; Groetsch, K. M.; Gerkin, R. C.; Wiltschko, A. B.; Riffell, J. A.; Dechering, K. J.
10.1101/2022.09.01.504601 — bioengineering — Posted on 2024-05-02
4796 The ATP-exporting channel Pannexin-1 promotes CD8+ T cell effector and memory responses
Vardam-Kaur, T.; Banuelos, A.; Gabaldon-Parish, M.; Macedo, B. G.; Salgado, C. L.; Wanhainen, K. M.; Zhou, M. H.; van Dijk, S.; Santiago-Carvalho, I.; Beniwal, A. S.; Leff, C. L.; Peng, C.; Tran, N. L.; Jameson, S. C.; Borges da Silva, H.
10.1101/2023.04.19.537580 — immunology — Posted on 2024-05-02
4797 Regulation of Leucine-Rich Repeat Kinase 2 by inflammation and IL-4
Dikovskaya, D.; Pemberton, R.; Taylor, M.; Tasegian, A.; Zenevicuite, K.; Sammler, E.; Howden, A. J.; Alessi, D. R.; Swamy, M.
10.1101/2024.04.29.591170 — immunology — Posted on 2024-05-02
4799 SLC35G1: A highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption
Mimura, Y.; Yasujima, T.; Inoue, K.; Akino, S.; Namba, C.; Kusuhara, H.; Sekiguchi, Y.; Ohta, K.; Yamashiro, T.; Yuasa, H.
10.1101/2024.04.29.591675 — physiology — Posted on 2024-05-02
4801 Integrin Mechanosensing relies on Pivot-clip Mechanism to Reinforce Cell Adhesion
Montes, A.; Barroso, A.; Wang, W.; O'Connell, G.; Buganza Tepole, A.; Mofrad, M.
10.1101/2023.12.13.571593 — biophysics — Posted on 2024-05-02
4803 PseudoCell: A Multi-Valued Logical Regulatory Network to Investigate Premature Senescence Dynamics and Heterogeneity
Pierdona, V.; Lavandoski, P.; Maurmann, R. M.; Borges, G. A.; Mombach, J. C. M.; Guma, F. T. C. R.; Barbe-Tuana, F. M.
10.1101/2023.07.20.549793 — bioinformatics — Posted on 2024-05-02
4805 Catalytic Redundancies and Conformational Plasticity Drives Selectivity and Promiscuity in Quorum Quenching Lactonases
Corbella, M.; Bravo, J.; Demkiv, A. O.; Calixto, A. R.; Sompiyachoke, K.; Bergonzi, C.; Elias, M. H.; Kamerlin, S. C. L.
10.1101/2024.05.01.592096 — biochemistry — Posted on 2024-05-01
4807 regionalpcs: improved discovery of DNA methylation associations with complex traits
Eulalio, T.; Sun, M. W.; Gevaert, O.; Greicius, M. D.; Montine, T. J.; Nachun, D.; Montgomery, S. B.
10.1101/2024.05.01.590171 — genomics — Posted on 2024-05-01
4808 Coleoid Cephalopods Demonstrate Asocial Path to the Evolution of Big Brains
Basava, K.; Bendixen, T.; Leonard, A.; George, N. L.; Vanhersecke, Z.; Omotosho, J.; Mather, J.; Muthukrishna, M.
10.1101/2024.05.01.592020 — evolutionary biology — Posted on 2024-05-01
4815 Metabolic immaturity of newborns and breast milk bile acids are the central determinants of heightened neonatal vulnerability to norovirus diarrhea
Peiper, A. M.; Morales, J.; Phophi, L.; Hu, Z.; Phillips, M.; Williams, C. G.; Subramanian, S.; Cross, M.; Iyer, N.; Nguyen, Q.; Newsome, R. C.; Jobin, C.; Langel, S. N.; Becker-Dreps, S.; Tan, X.-D.; Dawson, P. A.; Helm, E. W.; Bucardo, F.; Karst, S. M.
10.1101/2024.05.01.592031 — microbiology — Posted on 2024-05-01
4816 Emergence of metabolic coupling to the heterotroph Alteromonas promotes dark survival in Prochlorococcus
Coe, A.; Braakman, R.; Biller, S. J.; Arellano, A.; Bliem, C.; Vo, N. N.; von Emster, K.; Thomas, E.; DeMers, M.; Steglich, C.; Huisman, J.; Chisholm, S. W.
10.1101/2024.05.01.591941 — microbiology — Posted on 2024-05-01
4818 Engineered Ubiquitin Variants Mitigate Pathogenic Bacterial Ubiquitin Ligase Function
Dubrule, B. E.; Wagner, A.; Zhang, W.; Middleton, A. J.; Subramanian, A. S.; Eitzen, G.; Sidhu, S. S.; Bhavsar, A.
10.1101/2024.05.01.592009 — microbiology — Posted on 2024-05-01
4819 HCF101 is a novel component of the CIA cytosolic iron-sulfur synthesis pathway in the human pathogen Toxoplasma gondii
Renaud, E. A.; Maupin, A. J.; Berry, L.; Bals, J.; Bordat, Y.; Demolombe, V.; Rofidal, V.; Vignols, F.; Besteiro, S.
10.1101/2024.05.01.592079 — microbiology — Posted on 2024-05-01
4820 Diversity and impact of single-stranded RNA viruses in Czech Heterobasidion populations
Dalya, L. B.; Cerny, M.; de la Pena, M.; Poimala, A.; Vainio, E.; Hantula, J.; Botella, L.
10.1101/2024.05.01.591139 — microbiology — Posted on 2024-05-01
4821 Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle
Nguyen, T.-Q.; Hutter, C.; Markin, A.; Thomas, M. N.; Lantz, K.; Killian, M. L.; Janzen, G. M.; Vijendran, S.; Wagle, S.; Inderski, B.; Magstadt, D. R.; Li, G.; Diel, D. G.; Frye, E. A.; Dimitrov, K. M.; Swinford, A. K.; Thompson, A. C.; Snevik, K. R.; Suarez, D. L.; Spackman, E.; Lakin, S. M.; Ahola, S. C.; Johnson, K. R.; Baker, A. L.; Robbe-Austerman, S.; Torchetti, M. K.; Anderson, T. K.
10.1101/2024.05.01.591751 — microbiology — Posted on 2024-05-01
4822 Receptors Determine Lytic Phage Host Range in Pseudomonas aeruginosa
Mueller, D. M.; Pourtois, J.; Kim, K. M.; Targ, B.; McBride, R.; Bollyky, P.
10.1101/2024.04.30.591980 — microbiology — Posted on 2024-05-01
4823 Copy number variations of Plasmodium vivax DBP1, EBP/DBP2, and RBP2b in Duffy-positive and Duffy-negative Ethiopians
Pestana, K.; Ford, A.; Rama, R.; Abagero, B.; Kepple, D.; Tomida, J.; Popovici, J.; Yewhalaw, D.; Lo, E.
10.1101/2024.04.29.591731 — microbiology — Posted on 2024-05-01
4825 CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies
Richard, J.; Sannier, G.; Zhu, L.; Prevost, J.; Marchitto, L.; Benlarbi, M.; Beaudoin-Bussieres, G.; Sun, Y.; Hongil, K.; Chatterjee, D. A.; Medjahed, H.; Bourassa, C.; Delgado, G.-G.; Dube, M.; Kirchhoff, F.; Hahn, B. H.; Kumar, P.; Kaufmann, D. E.; Finzi, A.
10.1101/2024.05.01.592003 — microbiology — Posted on 2024-05-02
4828 A disengaging property of medial accumbens shell dopamine.
Valyear, M. D.; Eustachon, N. M.-L.; Alymova, I.; Tremblay, B. N.; Mitrikeski, N. M.; Britt, J. P.
10.1101/2023.11.29.569116 — neuroscience — Posted on 2024-05-02
4831 Cell morphogenesis via self-propelled treadmilling actin waves
Yagami, K.; Baba, K.; Minegishi, T.; Misu, S.; Katsuno-Kambe, H.; Okano, K.; Sakumura, Y.; Hosokawa, Y.; Inagaki, N.
10.1101/2024.02.28.582450 — cell biology — Posted on 2024-05-02
4832 Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity
Kitamura, A.; Fujimoto, A.; Kawashima, R.; Lyu, Y.; Sasaki, K.; Hamada, Y.; Moriya, K.; Kurata, A.; Takahashi, K.; Brielmann, R.; Bott, L. C.; Morimoto, R. I.; Kinjo, M.
10.1101/2022.05.22.493003 — molecular biology — Posted on 2024-05-02
4833 SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle
Herneisen, A. L.; Peters, M. L.; Smith, T. A.; Shortt, E.; Lourido, S.
10.1101/2023.10.30.564746 — microbiology — Posted on 2024-05-02
4835 Decoil: Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data
Giurgiu, M.; Wittstruck, N.; Rodriguez-Fos, E.; Chamorro Gonzalez, R.; Bruckner, L.; Krienelke-Szymansky, A.; Helmsauer, K.; Hartebrodt, A.; Koche, R. P.; Haase, K.; Reinert, K.; Henssen, A. G.
10.1101/2023.11.15.567169 — cancer biology — Posted on 2024-05-02
4836 PTBP2 promotes cell survival and autophagy in Chronic Myeloid Leukemia by stabilizing BNIP3
Barik, B.; Lama, S.; IS, S.; Chanda, S.; Biswas, S.; Biswas, G.; Mohapatra, S.; chakraborty, S.
10.1101/2024.01.26.577177 — cancer biology — Posted on 2024-05-02
4839 Sox9 marks limbal stem cells and is required for asymmetric cell fate switch in the corneal epithelium
Rice, G.; Farrelly, O.; Huang, S.; Kuri, P.; Curtis, E.; Ohman, L.; Li, N.; Lengner, C.; Lee, V.; Rompolas, P.
10.1101/2024.04.08.588195 — developmental biology — Posted on 2024-05-02
4842 Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration
Hahn, H.; Daly, C.; Little, J.; Perry-Hauser, N. A.; Flores-Espinoza, E.; Inoue, A.; Plouffe, B.; Thomsen, A. R. B.
10.1101/2022.09.27.509755 — cell biology — Posted on 2024-05-02
4843 The cellular Notch1 Protein Promotes KSHV reactivation in an Rta-dependent manner.
DeCotiis-Mauro, J.; Han, S. M.; Mello, H.; Goyeneche, C.; Marchesini-Tovar, G.; Jin, L.; Bellofatto, V.; Lukac, D. M.
10.1101/2022.10.21.513206 — microbiology — Posted on 2024-05-02
4845 Emotional Vocalizations Alter Behaviors and Neurochemical Release into the Amygdala
Ghasemahmad, Z.; Mrvelj, A.; Panditi, R.; Sharma, B.; Perumal, K. D.; Wenstrup, J. J.
10.1101/2022.07.02.498564 — neuroscience — Posted on 2024-05-02
4851 OmicsFootPrint: a framework to integrate and interpret multi-omics data using circular images and deep neural networks
Tang, X.; Prodduturi, N.; Thompson, K. J.; Weinshilboum, R. M.; O'Sullivan, C. C.; Boughey, J. C.; Tizhoosh, H.; Klee, E. W.; Wang, L.; Goetz, M. P.; Suman, V.; Kalari, K. R.
10.1101/2024.03.21.586001 — bioinformatics — Posted on 2024-05-01
4852 R2Dtool: Integration and visualization of isoform-resolved RNA features
Sethi, A. J.; Acera Mateos, P.; Hayashi, R.; Shirokikh, N. E.; Eyras, E.
10.1101/2022.09.23.509222 — bioinformatics — Posted on 2024-05-02
4854 Beyond guilty by association at scale: searching for causal variants on the basis of genome-wide summary statistics
He, Z.; Chu, B.; Yang, J.; Gu, J.; Chen, Z.; Liu, L.; Morrison, T.; Belloy, M. E.; Qi, X.; Hejazi, N.; Mathur, M.; Le Guen, Y.; Tang, H.; Hastie, T.; Ionita-laza, I.; Sabatti, C.; Candes, E.
10.1101/2024.02.28.582621 — genetics — Posted on 2024-05-02
4855 Targeted genotyping-by-sequencing of potato and data analysis with R/polyBreedR
Endelman, J. B.; Kante, M.; Lindqvist-Kreuze, H.; Kilian, A.; Shannon, L. M.; Caraza-Harter, M. V.; Vaillancourt, B.; Mailloux, K.; Hamilton, J. P.; Buell, C. R.
10.1101/2024.02.12.579978 — genomics — Posted on 2024-05-01
4857 Generators of the frequency-following response in the subthalamic nucleus: implications for non-invasive deep brain stimulation
Hnazaee, M. F.; Zhao, H.; Hao, S.; Moorkens, A.; Lambert, C.; Zhan, S.; Li, D.; Sun, B.; Litvak, V.; Cao, C.
10.1101/2024.04.30.589054 — neuroscience — Posted on 2024-05-01
4858 Assembly, comparative analysis, and utilization of a single haplotype reference genome for soybean
Espina, M. J. C.; Lovell, J. T.; Jenkins, J. W.; Shu, S.; Sreedasyam, A.; Jordan, B. D.; Webber, j.; Boston, L.; Bruna, T.; Talag, J.; Goodstein, D. M.; Grimwood, J.; Stacey, G.; Cannon, S. B.; Lorenz, A.; Schmutz, J.; Stupar, R. M.
10.1101/2024.04.26.591401 — plant biology — Posted on 2024-05-01
4859 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.
10.1101/2023.06.25.546428 — biophysics — Posted on 2024-05-01
4861 Split-Transformer Impute (STI): A Transformer Framework for Genotype Imputation
Mowlaei, M. E.; Li, C.; Jamialahmadi, O.; Dias, R.; Chen, J.; Jamialahmadi, B.; Rebbeck, T. R.; Carnevale, V.; Kumar, S.; Shi, X.
10.1101/2023.03.05.531190 — genomics — Posted on 2024-05-01
4862 A global atlas of soil viruses reveals unexplored biodiversity and potential biogeochemical impacts
Graham, E. B.; Camargo, A. P.; Wu, R.; Neches, R. Y.; Nolan, M.; Paez-Espino, D.; Kyrpides, N.; Jansson, J. K. K.; McDermott, J. E.; Hofmockel, K. S.; Soil Virosphere Consortium,
10.1101/2023.11.02.565391 — ecology — Posted on 2024-05-01
4863 Cholesterol Metabolite 27-Hydroxycholesterol Enhances the Secretion of Cancer Promoting Extracellular Vesicles by a Mitochondrial ROS-Induced Impairment of Lysosomal Function
Das Gupta, A.; Park, J.; Sorrells, J. E.; Kim, H.; Krawczynska, N.; Gamage, H. E. V.; Nelczyk, A. T.; Boppart, S. A.; Boppart, M. D.; Nelson, E. R.
10.1101/2024.05.01.591500 — cell biology — Posted on 2024-05-01
4864 A CRISPR-dCas13 RNA-editing tool to study alternative splicing
Nunez-Alvarez, Y.; Espie--Caullet, T.; Buhagiar-Labarchede, G.; Rubio-Zulaika, A.; Alonso-Maranon, J.; Perez-Luna, E.; Blazquez, L.; Luco, R.
10.1101/2022.05.24.493209 — molecular biology — Posted on 2024-05-01
4866 Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis
Maio, M.; Barros, J.; Joly, M.; Vahlas, Z.; Marin Franco, J. L.; Genoula, M.; Monard, S.; Vecchione, M. B.; Fuentes, F.; Gonzalez Polo, V.; Quiroga, M. F.; Vermeulen, M.; Vu Manh, T. P.; Argüello, R. J.; Inwentarz, S.; Musella, R.; Ciallella, L.; Gonzalez Montaner, P.; Palmero, D.; Lugo Villarino, G.; Sasiain, M. d. C.; Neyrolles, O.; Verollet, C.; Balboa, L.
10.1101/2023.04.03.535400 — immunology — Posted on 2024-05-01
4871 A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants
Papageorgiou, G.; Ibrahim, E.-C.; Maxson, G.; Gorgievski, V.; Lozano, E.; Belzeaux, R.; Carmody, T.; Tzavara, E. T.; Trivedi, M. T.; Mellios, N.
10.1101/2024.04.30.591973 — neuroscience — Posted on 2024-05-01
4872 Alterations of PINK1-PRKN signaling in mice during normal aging
Baninameh, Z.; Watzlawik, J. O.; Hou, X.; Richardson, T.; Kurchaba, N. W.; Yan, T.; Di Florio, D. N.; Fairweather, D.; Kang, L.; Nguyen, J. H.; Kanekiyo, T.; Dickson, D. W.; Noda, S.; Sato, S.; Hattori, N.; Goldberg, M. S.; Ganley, I. G.; Stauch, K. L.; Fiesel, F. C.; Springer, W.
10.1101/2024.04.29.591753 — neuroscience — Posted on 2024-05-01
4874 Genetic code expansion, click chemistry, and light-activated PI3K reveal details of membrane protein trafficking downstream of receptor tyrosine kinases
Koh, D.-S.; Stratiievska, A.; Jana, S.; Otto, S. C.; Swanson, T. M.; Nhim, A.; Carlson, S.; Raza, M.; Naves, L. A.; Senning, E. N.; Mehl, R.; Gordon, S. E.
10.1101/2023.08.29.555449 — physiology — Posted on 2024-05-01
4875 APOBEC3 mutagenesis drives therapy resistance in breast cancer
Gupta, A.; Gazzo, A.; Selenica, P.; Safonov, A.; Pareja, F.; da Silva, E. M.; Brown, D. N.; Zhu, Y.; Patel, J.; Blanco-Heredia, J.; Stefanovska, B.; Carpenter, M. A.; Pei, X.; Frosina, D.; Jungbluth, A. A.; Ladanyi, M.; Curigliano, G.; Weigelt, B.; Riaz, N.; Powell, S. N.; Razavi, P.; Harris, R. S.; Reis-Filho, J. S.; Marra, A.; Chandarlapaty, S.
10.1101/2024.04.29.591453 — cancer biology — Posted on 2024-05-01
4876 Biostimulation methods based on chemical communication improve semen quality in male breeder rabbits.
Villamayor, P. R.; Yanez, U.; Gullon, J.; Sanchez-Quinteiro, P.; Pena, A. I.; Becerra, J. J.; Herradon, P. G.; Martinez, P.; Quintela, L. A.
10.1101/2024.04.30.591951 — animal behavior and cognition — Posted on 2024-05-01
4879 Histological and gene-expression analyses of pyloric sphincter formation during stomach metamorphosis in Xenopus laevis
Nagura, K.; Ikeda, T.; Hasebe, T.; Satou-Kobayashi, Y.; Udagawa, S.; Shigenobu, S.; Ishizuya-Oka, A.; Taira, M.
10.1101/2024.04.29.591326 — developmental biology — Posted on 2024-05-01
4880 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids
Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Wang, M.; Ren, W.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.
10.1101/2023.04.25.538102 — cell biology — Posted on 2024-05-01
4883 The ANTsX Ecosystem for Mapping the Mouse Brain
Tustison, N. J.; Chen, M.; Kronman, F. N.; Duda, J. T.; Gamlin, C.; Tustison, M. G.; Kunst, M.; Dalley, R.; Sorensen, S. A.; Wang, Q.; Ng, L.; Kim, Y.; Gee, J. C.
10.1101/2024.05.01.592056 — neuroscience — Posted on 2024-05-01
4886 Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy
Ji, C.; Yang, X.; Eleish, M.; Jiang, Y.; Tetlow, A.; Song, S.; Martin-Avila, A.; Wu, Q.; Zhou, Y.; Gan, W.; Lin, Y.; Sigurdsson, E. M.
10.1101/2024.04.29.591735 — neuroscience — Posted on 2024-05-01
4887 Layer-specific control of inhibition by NDNF interneurons
Naumann, L. B.; Hertäg, L.; Müller, J.; Letzkus, J. J.; Sprekeler, H.
10.1101/2024.04.29.591728 — neuroscience — Posted on 2024-05-01
4888 The retina's neurovascular unit: Mueller glial sheaths and neuronal contacts
Grimes, W. S.; Berson, D. M.; Sabnis, A.; Hoon, M.; Sinhah, R.; Tian, H.; Diamond, J. S.
10.1101/2024.04.30.591885 — neuroscience — Posted on 2024-05-01
4889 A survival-critical role for Drosophila giant interneurons during predation
Chai, C. M.; Morrow, C.; Parikh, D. D.; von Reyn, C. R.; Leonardo, A.; Card, G. M.
10.1101/2024.04.30.591368 — neuroscience — Posted on 2024-05-01
4896 Distinct anatomical and functional corticospinal inputs innervate different spinal neuron types
Fageiry, S.; Warriner, C. L.; Loper, J.; Paninski, L.; Reardon, T.; Jessell, T. M.; Costa, R. M.; Miri, A.
10.1101/2024.04.29.591683 — neuroscience — Posted on 2024-05-01
4897 Coordination and persistence of aggressive visual communication in Siamese fighting fish
Everett, C. P.; Norovich, A. L.; Burke, J. E.; Whiteway, M. R.; Shih, P.-Y.; Zhu, Y.; Paninski, L.; Bendesky, A.
10.1101/2024.04.29.591330 — neuroscience — Posted on 2024-05-01
4899 A function of Spalt proteins in heterochromatin organization and maintenance of genomic DNA integrity
Ostale, C. M.; Azpiazu, N.; Peropadre, A.; Martin, M.; Ruiz-Losada, M.; Lopez-Varea, A.; Viales, R. R.; Girardot, C.; Furlong, E. E.; de Celis, J. F.
10.1101/2024.04.30.591908 — developmental biology — Posted on 2024-05-01
4901 Action potential propagation speed compensates for traveling distance in the human retina
Bucci, A.; Büttner, M.; Domdei, N.; Diggelmann, R.; Rosselli, F. B.; Znidaric, M.; Cowan, C. S.; De Gennaro, M.; Harmening, W.; Hierlemann, A.; Roska, B.; Franke, F.
10.1101/2024.04.30.591867 — neuroscience — Posted on 2024-05-01
4902 Exploring Neuroscience Researchers' Trust in Preprints through Citation Analysis
Rasuli, B.; Seyfzadehdarabad, F.; Cardone, P.; Thibaut, A.; Gosseries, O.
10.1101/2024.04.29.591455 — neuroscience — Posted on 2024-05-01
4904 Generalization in motor learning: learning bimanual coordination with one hand
Wang, Y.; Weinrich, M. M.; Lei, Y.; Wright, D. L.; Sandhu, M. S.; Buchanan, J. J.; Kennedy, D. M.
10.1101/2024.04.29.591705 — neuroscience — Posted on 2024-05-01
4912 Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes in R6/2 mice
Simmons, D. A.; Selvaraj, S.; Chen, T.; Cao, G.; Sauto Camelo, T.; McHugh, T. L. M.; Gonzalez, S.; Martin, R.; Simanauskaite, J.; Uchida, N.; Porteus, M.; Longo, F. M.
10.1101/2024.05.01.592095 — neuroscience — Posted on 2024-05-01
4913 Lateral Prefrontal Theta Oscillations Causally Drive a Computational Mechanism Underlying Conflict Expectation and Adaptation
Martinez-Molina, M. P.; Valdebenito-Oyarzo, G.; Soto-Icaza, P.; Zamorano, F.; Figueroa-Vargas, A.; Carvajal-Paredes, P.; Stecher, X.; Salinas, C.; Valero-Cabre, A.; Polania, R.; Billeke, P.
10.1101/2024.04.30.591918 — neuroscience — Posted on 2024-05-01
4914 Identification of Fibrinogen as a Plasma Protein Binding Partner for Lecanemab Biosimilar IgG: Implications for Alzheimer's Disease Therapy
Bellier, J.-P.; Roman, A.; Christiano, C.; Anzai, J. A.; Moreno, S.; Campbell, E. C.; Godwin, L.; Li, A.; Chen, A.; Alan, S. M.; Saba, A.; Yoo, H. b.; Yang, H.-S.; Chhatwal, J. P.; Selkoe, D. J.; Liu, L.
10.1101/2024.05.01.591892 — neuroscience — Posted on 2024-05-01
4918 Neuronal downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease hallmarks
Coulon, A.; Rabiller, F.; Takalo, M.; Roy, A.; Martiskainen, H.; Siedlecki-Wullich, D.; Mendes, T.; Lemeu, C.; Carvalho, L.-I.; Ehrardt, A.; Melo de Ferias, A. R.; Hulsman, M.; Najdek, C.; Lannette-Weimann, N.; Freire-Regatillo, A.; Amouyel, P.; Charbonnier, C.; Dols-Icardo, O.; Jeskanen, H.; Kuulasmaa, T.; Kurki, M.; Hardy, J.; Wagner, M.; Heikkinen, S.; Holstege, H.; Makinen, P.; Nicolas, G.; Mead, S.; Wagner, M.; Ramirez, A.; Rauramaa, T.; Palotie, A.; Sims, R.; Soininen, H.; van Swieten, J.; Williams, J.; Willman, R.-M.; Bellenguez, C.; Grenier-Boley, B.; Gelle, C.; Lambert, E.; Ayral, A.-
10.1101/2024.04.29.591575 — neuroscience — Posted on 2024-05-01
4922 Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study
Labounek, R.; Bondy, M. T.; Paulson, A. L.; Bedard, S.; Abramovic, M.; Alonso-Ortiz, E.; Atcheson, N. T.; Barlow, L. R.; Barry, R. L.; Barth, M.; Battiston, M.; Buchel, C.; Budde, M. D.; Callot, V.; Combes, A.; De Leener, B.; Descoteaux, M.; Loureiro de Sousa, P.; Dostal, M.; Doyon, J.; Dvorak, A. V.; Eippert, F.; Epperson, K. R.; Epperson, K. S.; Freund, P.; Finsterbusch, J.; Foias, A.; Fratini, M.; Fukunaga, I.; Gandini Wheeler-Kingshott, C. A. M.; Germani, G.; Gilbert, G.; Giove, F.; Grussu, F.; Hagiwara, A.; Henry, P.-G.; Horak, T.; Hori, M.; Joers, J. M.; Kamiya, K.; Karbasforoushan, H.;
10.1101/2024.04.29.591421 — neuroscience — Posted on 2024-05-01
4924 From electrophysiology to drink: Adolescent alcohol consumption predicted by differences in functional connectivity and neuroanatomy
del Cerro Leon, A.; Anton Toro, L. F.; Shpakivska Bilan, D.; Uceta, M.; Santos Mayo, A.; Cuesta, P.; Bruna, R.; Garcia Moreno, L. M.; Maestu, F.
10.1101/2024.04.29.591615 — neuroscience — Posted on 2024-05-01
4925 Excitatory and inhibitory synapses form a tight subcellular balance along dendrites that decorrelates over development
Horton, S.; Mastrolia, V.; Jackson, R.; Kemlo, S.; Pereira Machado, P.; Alejandra Carbajal, M.; Hindges, R.; Fleck, R.; Aguiar, P.; Neves, G.; Burrone, J.
10.1101/2024.04.30.591814 — neuroscience — Posted on 2024-05-01
4927 Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption in mice, in part through hippocampal thyroid hormone signaling.
Helbling, J.-C.; Ginieis, R.; Mortessagne, P.; Ruiz-Gayo, M.; Ducourneau, E. G.; Ciocca, D.; Boulete, I.-M.; Favereaux, A.; Ces, A.; Montalban, E.; Capuron, L.; jeanneteau, f.; Ferreira, G.; Challet, E.; Moisan, M.-P.
10.1101/2024.04.29.591510 — neuroscience — Posted on 2024-05-01
4928 High-plex Digital Spatial Profiling Identifies Subregion-Dependent Directed Proteome Changes Across Multiple Variants of Dementia
Bolen, M. L.; Menees, K. B.; Merchak, A. R.; Gearing, M.; Gong, J.; Ren, Y.; Murray, M. E.; McEachin, Z. T.; Tansey, M. G.
10.1101/2024.04.29.591721 — neuroscience — Posted on 2024-05-01
4929 Voluntary adolescent alcohol exposure does not increase adulthood consumption of alcohol in multiple mouse and rat models
Sicher, A. R.; Liss, A.; Vozella, V.; Seemiller, L. R.; Springer, M.; Starnes, W. D.; Griffith, K. R.; Smith, G. C.; Astefanous, A.; Roberto, M.; Varodayan, F. P.; Crowley, N. A.
10.1101/2024.04.30.591674 — neuroscience — Posted on 2024-05-01
4932 Endogenous opioid system modulates proximal and distal threat signals in the human brain
Seppala, K.; Putkinen, V. J.; Harju, H.; Rebelos, E.; Hirvonen, J.; Helin, S.; Rajander, J.; Karlsson, H. K.; Saunavaara, J.; Hyona, J.; Nummenmaa, L.
10.1101/2024.04.30.591095 — neuroscience — Posted on 2024-05-01
4936 A first insight into the developability of an IgG3: A combined computational and experimental approach
Armstrong, G. B.; Lewis, A.; Shah, V.; Taylor, P.; Jamieson, C.; Burley, G. A.; Lewis, W. J.; Rattray, Z.
10.1101/2024.04.29.591602 — bioengineering — Posted on 2024-05-01
4942 Segmental regulation of intestinal motility by colitis and the adaptive immune system in the ileum and colon
Gomez-Bris, R.; Rodriguez-Rodriguez, P.; Ortega-Zapero, M.; Ruvira, S.; Saez, A.; Arribas, S. M.; Gonzalez-Granado, J. M.
10.1101/2024.04.29.591625 — immunology — Posted on 2024-05-01
4944 Connectivity at fine scale: mapping structural connective fields by tractography of short association fibres in vivo
Movahedian Attar, F.; Kirilina, E.; Edwards, L. J.; Haenelt, D.; Pine, K. J.; Trampel, R.; Chaimow, D.; Weiskopf, N.
10.1101/2024.04.30.591798 — neuroscience — Posted on 2024-05-01
4945 Nature exposure induces hypoalgesia by acting on nociception-related neural processing
Steininger, M. O.; White, M. P.; Lengersdorff, L.; Zhang, L.; Smalley, A. J.; Kuehn, S.; Lamm, C.
10.1101/2024.04.29.591600 — neuroscience — Posted on 2024-05-01
4947 Bilateral field advantage of spatial attention in macaque lateral prefrontal cortex
Martinez-Trujillo, J. C.; Kadijani, M. N.; Machanda, K.; Mody, S.; Backen, T.; Treue, S.
10.1101/2024.04.29.591631 — neuroscience — Posted on 2024-05-01
4949 Ventral pallidal GABAergic neurons drive consumption in male, but not female rats
Scott, A.; Paulson, A.; Prill, C.; Kermoade, K.; Newell, B.; Richard, J. M.
10.1101/2024.04.30.591876 — neuroscience — Posted on 2024-05-01
4953 Unveiling the crucial role of betaine: Modulation of GABA homeostasis via SLC6A1 transporter (GAT1)
Bhatt, M.; Lazzarin, E.; Alberto e Silva, A. S.; Domingo, G.; Zerlotti, R.; Gradisch, R.; Bazzone, A.; Sitte, H. H.; Stockner, T.; Bossi, E.
10.1101/2024.04.30.591809 — neuroscience — Posted on 2024-05-01
4956 Magnesium hydroxide nanoneedles derived from Anthocleista schweinfurthii Gilg (Loganiaceae) support mesenchymal stromal cell proliferation and wound healing
Eya ane Meva, F.; Pereira, R.; Ngnihamye, S. E.; Armel Florian, T. N.; Ntoumba, A. A.; Hzounda Fokou, j. B.; Beglau, T. H. Y.; Fetzer, M. N.; Kaul, M.; Schlierf, B.; Mintang Fongang, U. A.; Belle Ebanda Kedi, P.; Fannang, S. V.; Herrmann, M.; Janiak, C.
10.1101/2024.04.29.591621 — pharmacology and toxicology — Posted on 2024-05-01
4957 Biocompatibility of KAPs-Depleted Residual Hair
Meer, A.; Mathews, A.; Cabral, M.; Tarabokija, A.; Carroll, E.; Chaudhry, H.; Paszek, M.; Radecker, N.; Palaia, T.; de Guzman, R. C.
10.1101/2024.04.29.591537 — bioengineering — Posted on 2024-05-01
4960 Single-cell transcriptomics reveals evolutionary reconfiguration of embryonic cell fate specification in the sea urchin Heliocidaris erythrogramma
Massri, A. J.; Berrio, A.; Afanassiev, A.; Greenstreet, L.; Pipho, K.; Byrne, M.; Schiebinger, G.; McClay, D. R.; Wray, G. A.
10.1101/2024.04.30.591752 — evolutionary biology — Posted on 2024-05-01
4961 How light at night sets the circalunar clock in the marine midge Clunio marinus
Peralta, C. M.; Feunteun, E.; Guillaudeau, J.; Brisevac, D.; Kaiser, T. S.
10.1101/2024.04.30.591642 — ecology — Posted on 2024-05-01
4963 Anomalous diffusion analysis reveals cooperative locomotion of adult parasitic nematodes in sex-mixed groups.
Leben, R.; Rausch, S.; Elomaa, L.; Hauser, A. E.; Weinhart, M.; Fischer, S. C.; Stark, H.; Hartmann, S.; Niesner, R. A.
10.1101/2024.04.29.591609 — biophysics — Posted on 2024-05-01
4964 Bioinformatic evaluation of the potential oral-gut translocation of periodontal pathogens in patients with colorectal polyps
Takahashi, N.; Yamaguchi, M.; Sato, K.; Tsuzuno, T.; Mineo, S.; Nakajima, N.; Takahashi, K.; Sato, H.; Miyazawa, H.; Aoki-Nonaka, Y.; Ito, Y.; Taniguchi, K.; Terai, S.; Ito, K.; Tabeta, K.
10.1101/2024.04.29.591540 — bioinformatics — Posted on 2024-05-01
4965 An integrative taxonomy approach reveals Saccharomyces chiloensis sp. nov. as a newly discovered species from Coastal Patagonia
Pena, T. A.; Villarreal, P.; Agier, N.; Chiara, M. D.; Barria, T.; Urbina, K.; Villarroel, C. A.; Santos, A. R. O.; Rosa, C. A.; Nespolo, R. F.; Liti, G.; Fischer, G.; Cubillos, F.
10.1101/2024.04.29.591617 — genetics — Posted on 2024-05-01
4969 Crystallographic fragment screen of Enterovirus D68 3C protease and iterative design of lead-like compounds using structure-guided expansions
Lithgo, R. M.; Tomlinson, C. W. E.; Fairhead, M.; Winokan, M.; Thompson, W.; Wild, C.; Aschenbrenner, J.; Balcomb, B.; Marples, P. G.; Chandran, A. V.; Golding, M. N.; Koekemoer, L.; Williams, E. P.; Wang, S.; Ni, X.; MacLean, E. M.; Giroud, C.; Zarganes-Tzitzikas, T.; Schutzer de Godoy, A.; Xavier, M.-A.; Walsh, M.; Fearon, D.; von Delft, F.
10.1101/2024.04.29.591650 — biochemistry — Posted on 2024-05-01
4970 Most human DNA replication initiation is dispersed throughout the genome with only a minority within previously identified initiation zones
Carrington, J. T.; Wilson, R. H.; Thiyagarajan, S.; Barker, T.; Catchpole, L.; Durrant, A.; Knitlhoffer, V.; Watkins, C.; Gharbi, K.; Nieduszynski, C. A.
10.1101/2024.04.28.591325 — genomics — Posted on 2024-05-01
4971 Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site
Khayenko, V. M.; Makbul, C.; Schulte, C.; Hemmelmann, N.; Kachler, S.; Böttcher, B.; Maric, H. M.
10.1101/2024.04.29.591677 — microbiology — Posted on 2024-05-01
4972 New insights into the echinocandin resistance in Candida spp. in the clinical setting
Gedeon, A.; Kalboussi, Y.; Bigot, J.; Le, V.; Dannaoui, E.; Vellaissamy, S.; Antignac, M.; Petrella, S.; Hennequin, C.; Guitard, J.
10.1101/2024.04.29.591739 — microbiology — Posted on 2024-05-01
4973 Exploring the Transcriptomic Profile of Human Monkeypox Virus via CAGE and Native RNA Sequencing Approaches
Boldogkoi, Z.; Nagy, G. A.; Tombacz, D.; Prazsak, I.; Csabai, Z.; Dörmo, A.; Gulyas, G.; Kemenesi, G.; Toth, G. E.; Holoubek, J.; Ruzek, D.; Kakuk, B.
10.1101/2024.04.29.591702 — microbiology — Posted on 2024-05-01
4974 IFI207, a young and fast-evolving protein, controls retroviral replication via the STING pathway
Moran, E. A.; Salas-Briceno, K.; Zhao, W.; Enya, T.; Aguilera, A.; Acosta, I.; Alonzo, F.; Kiani, D.; Behnsen, J.; Alvarez, C.; Keane, T.; Adams, D. J.; Lilue, J.; Ross, S. R.
10.1101/2024.04.30.591891 — immunology — Posted on 2024-05-01
4975 MDM2 stabilization of Notch intracellular domain upon DNA damage plays a major role in non-small cell lung carcinoma response to platinum chemotherapy
Bernardo, S.; Thomas, Q. D.; Mancini, M.; Santos, A.; Rasamizafy, S. F.; Maacha, A. M.; Giry, A.; Bousquet-Mur, e.; Papon, L.; Goussard, M.; Fremin, C.; Pasquier, A.; Rodriguez, M.; Travert, C.; Pujol, J. L.; Linares, L. K.; Heron-Milhavet, L.; Djiane, A.; Ferrer, I.; Paz-Ares, L.; Quantin, X.; Montuenga, L. M.; Tourriere, H.; Maraver, A.
10.1101/2024.04.29.591624 — cancer biology — Posted on 2024-05-01
4979 Perturbation-Specific Transcriptional Mapping facilitates unbiased target elucidation of antibiotics
Romano, K. P.; Bagnall, J.; Warrier, T.; Sullivan, J.; Ferrara, K.; Orzechowski, M.; Nguyen, P.; Raines, K.; Livny, J.; Shoresh, N.; Hung, D.
10.1101/2024.04.25.590978 — genomics — Posted on 2024-05-01
4982 What unexplored means: Mapping undersampled regions in natural history collections
Chakrabarty, P.; Ball, L.; Rodriguez Machado, S.; Paredes-Burneo, D.; Rutledge, S.; Boyd, D.; Vander Pluym, D.; Babb-Biernacki, S.; Chipps, A.; Ozturk, R.; Terzi, Y.
10.1101/2024.02.09.579602 — ecology — Posted on 2024-05-01
4984 Two opposing roles for Bmp signalling in the development of electrosensory lateral line organs
Campbell, A. S.; Minarik, M.; Franek, R.; Fucikova, M.; Havelka, M.; Gela, D.; Psenicka, M.; Baker, C. V. H.
10.1101/2024.03.07.583945 — developmental biology — Posted on 2024-05-01
4985 Deciphering the phospho-signature induced by hepatitis B virus in primary human hepatocytes
Pastor, F.; Charles, E.; Belmudes, L.; Chabrolles, H.; Cescato, M.; Rivoire, M.; Burger, T.; Passot, G.; Durantel, D.; Lucifora, J.; Coute, Y.; SALVETTI, A.
10.1101/2024.04.10.588822 — microbiology — Posted on 2024-05-01
4986 Coenzyme A governs proinflammatory macrophage metabolism
Timblin, G. A.; Tharp, K. M.; Hoeve, J. t.; Kantner, D. S.; Baydemir, I.; Noel, E. A.; Khantwal, C.; Singh, P. K.; Farahzad, J. N.; Dominguez-Andres, J.; Vance, R. E.; Snyder, N. W.; Weaver, V. M.
10.1101/2022.08.30.505732 — immunology — Posted on 2024-05-01
4987 Chronic activation of a negative engram induces behavioral and cellular abnormalities
Jellinger, A. L.; Suthard, R. L.; Yuan, B.; Surets, M.; Ruesch, E. A.; Caban, A. J.; Liu, X. S.; Shpokayte, M.; Ramirez, S.
10.1101/2023.11.15.567268 — neuroscience — Posted on 2024-05-01
4988 A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease
Kallweit, L.; Saternos, H.; Hamlett, E. D.; Gilmore, A.; Granholm, A.-C.; Horowitz, S.
10.1101/2023.10.02.560545 — neuroscience — Posted on 2024-05-01
4991 Bundle Analytics based Data Harmonization for Multi-Site Diffusion MRI Tractometry
Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y. W.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.
10.1101/2024.02.03.578764 — neuroscience — Posted on 2024-05-01
4994 A graded neonatal mouse model of necrotizing enterocolitis demonstrates that mild enterocolitis is sufficient to activate microglia and increase cerebral cytokine expression.
Sha, C.; VanBrunt, T.; Kudria, J.; Schmidt, D.; Yurovsky, A.; Bandovic, J.; Giarrizzo, M.; Bialkowska, A. B.; Wollmuth, L.; Speer, E.; Hsieh, H.
10.1101/2023.08.03.551849 — physiology — Posted on 2024-05-01
4996 Landing force reveals new form of motion-induced sound camouflage in a wild predator.
Schalcher, K.; Milliet, E.; Sechaud, R.; Buehler, R.; Almasi, B.; Pottier, S.; Becciu, P.; Roulin, A.; Shepard, E. L. C.
10.1101/2023.03.07.531523 — animal behavior and cognition — Posted on 2024-05-01
4998 Effects of environmental change on population growth: monitoring time-varying carrying capacity in free-ranging spotted hyenas
Bailey, L. D.; Höner, O. P.; Davidian, E.; Dheer, A.; Radchuk, V.; Walter, L. F.; White, E. W.; Courtiol, A.
10.1101/2024.04.11.589105 — ecology — Posted on 2024-05-01