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Archive, 2020-06

2 Altered Affective Behaviors in Casein Kinase 1 Epsilon Mutant Mice
Zhou, L.; Fitzpatrick, K.; Olker, C.; Vitaterna, M. H.; Turek, F. W.
10.1101/2020.06.26.158600 — neuroscience — Posted on 2020-06-30
4 R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements
Ellis, D. A.; Reyes-Martin, F.; Rodriguez-Lopez, M.; Cotobal Martin, C.; Sun, X.-M.; Jeffares, D. C.; Marguerat, S. B.; Tallada, V. A.; Bahler, J.
10.1101/522524 — genomics — Posted on 2020-06-30
5 Geographic and environmental contributions to genomic divergence in mangrove forests
Silva, M. F. d.; Cruz, M. V.; Junior, J. d. D. V.; Zucchi, M. I.; Mori, G. M.; de Souza, A. P.
10.1101/2020.01.08.889717 — evolutionary biology — Posted on 2020-06-30
9 Local Field Potentials in a Pre-motor Region Predict Learned Vocal Sequences
Brown, D. E.; Chavez, J. I.; Nguyen, D. H.; Kadwory, A.; Voytek, B.; Arneodo, E.; Gentner, T. Q.; Gilja, V.
10.1101/2020.06.30.179861 — neuroscience — Posted on 2020-06-30
10 Multiple types of navigational information are diffusely and independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-06-30
12 Requirement of Irf6 and Esrp1/2 in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish
Carroll, S. H.; Macias Trevino, C.; Li, E. B.-H.; Kawasaki, K.; Alhazmi, N.; Hallett, S.; Cotney, J.; Carstens, R. P.; Liao, E. C.
10.1101/2020.06.14.149773 — developmental biology — Posted on 2020-06-30
14 Quantitative profiling of protease specificity.
Ratnikov, B. I.; Cieplak, P.; Remacle, A.; Nguyen, E.; Smith, J. W.
10.1101/2020.06.30.179820 — biochemistry — Posted on 2020-06-30
15 Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity
Mellis, I. A.; Edelstein, H. I.; Truitt, R.; Beck, L. E.; Symmons, O.; Goyal, Y.; Dunagin, M. C.; Linares Saldana, R. A.; Shah, P. P.; Yang, W.; Jain, R.; Raj, A.
10.1101/2020.06.11.147207 — systems biology — Posted on 2020-06-30
19 Split-HaloTag Imaging Assay for in vivo 3D-Microscopy and Subdiffractional Analyses of Protein-Protein Interactions
Meinen, R.; Weber, J. N.; Albrecht, A.; Matis, R.; Behnecke, M.; Tietge, C.; Frank, S.; Schulze, J.; Buschmann, H.; Walla, P. J.; Mendel, R. R.; Haensch, R.; Kaufholdt, D.
10.1101/2020.06.08.139378 — plant biology — Posted on 2020-06-30
20 Physiological properties and tailored feeds to support aquaculture of marbled crayfish in closed systems
Toenges, S.; Masagounder, K.; Gutekunst, J.; Lohbeck, J.; Miller, A. K.; Boehl, F.; Lyko, F.
10.1101/2020.02.25.964114 — physiology — Posted on 2020-06-30
21 Database for drug metabolism and comparisons, NICEdrug.ch, aids discovery and design
MohammadiPeyhani, H.; Chiappino-Pepe, A.; Haddadi, K.; Hafner, J.; Hadadi, N.; Hatzimanikatis, V.
10.1101/2020.05.28.120782 — pharmacology and toxicology — Posted on 2020-06-30
23 Associations between neonatal cry acoustics and visual attention during the first year
Kivinummi, A.; Naithani, G.; Tammela, O.; Virtanen, T.; Kurkela, E.; Alhainen, M.; Niehaus, D. J.; Lachman, A.; Leppänen, J.; Peltola, M.
10.1101/658732 — neuroscience — Posted on 2020-06-30
24 Neural representations of social valence bias economic interpersonal choices
Diaz-Gutierrez, P.; Arco, J. E.; Alguacil, S.; Gonzalez-Garcia, C.; Ruz, M.
10.1101/355115 — neuroscience — Posted on 2020-06-30
27 Structure of the full kinetoplastids mitoribosome and insight on its large subunit maturation
Soufari, H.; Waltz, F.; Parrot, C.; Durrieu, S.; Bochler, A.; Kuhn, L.; Sissler, M.; Hashem, Y.
10.1101/2020.05.02.073890 — molecular biology — Posted on 2020-06-30
32 Treerecs: an integrated phylogenetic tool, from sequences to reconciliations
Comte, N.; Morel, B.; Hasic, D.; Gueguen, L.; Boussau, B.; Daubin, V.; Penel, S.; Scornavacca, C.; Gouy, M.; Stamatakis, A.; Tannier, E.; Parsons, D.
10.1101/782946 — bioinformatics — Posted on 2020-06-30
34 Bacterial protein domains with a novel Ig-like fold bind human CEACAM receptors
van Sorge, N. M.; Bonsor, D. A.; Deng, L.; Lindahl, E.; Schmitt, V.; Lyndin, M.; Schmidt, A.; Nilsson, O. R.; Brizuela, J.; Boero, E.; Sundberg, E. J.; van Strijp, J.; Doran, K. S.; Singer, B. S.; Lindahl, G.; McCarthy, A. J.
10.1101/2020.06.09.141622 — microbiology — Posted on 2020-06-30
36 Heh2/Man1 may be an evolutionarily conserved sensor of NPC assembly state
Borah, S.; Thaller, D. J.; Hakhverdyan, Z.; Rodriguez, E. C.; Rout, M. P.; King, M. C.; Lusk, C. P.
10.1101/2020.06.29.178129 — cell biology — Posted on 2020-06-30
38 Genome-scale genetic screening identifies PRMT1 as a critical vulnerability in castration-resistant prostate cancer
Tang, S.; Metaferia, N. Y.; Nogueira, M. F.; Gelbard, M. K.; Abou Alaiwi, S.; Seo, J.-H.; Hwang, J. H.; Strathdee, C. A.; Baca, S. C.; Li, J.; AbuHammad, S.; Zhang, X.; Doench, J. G.; Hahn, W. C.; Takeda, D. Y.; Freedman, M. L.; Choi, P. S.; Viswanathan, S. R.
10.1101/2020.06.17.156034 — cancer biology — Posted on 2020-06-30
45 A FIJI Macro for quantifying pattern in extracellular matrix
Wershof, E.; Park, D.; Barry, D. J.; Jenkins, R. P.; Rullan, A.; Wilkins, A.; Roxanis, I.; Anderson, K. I.; Bates, P. A.; Sahai, E.
10.1101/867507 — cancer biology — Posted on 2020-06-30
48 Revival of light-evoked neuronal signals in the post-mortem mammalian and human retina
Abbas, F.; Becker, S.; Jones, B. W.; Mure, L. S.; Panda, S.; Hanneken, A.; Vinberg, F.
10.1101/2020.06.30.180497 — neuroscience — Posted on 2020-06-30
49 A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2
Ponce-Rojas, J. C.; Costello, M. S.; Proctor, D. A.; Kosik, K. S.; Wilson, M. Z.; Arias, C.; Acosta-Alvear, D.
10.1101/2020.06.29.178384 — molecular biology — Posted on 2020-06-30
50 A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
Malimova, M.; Sidhom, E.-H.; Satyam, A.; Dvela-Levitt, M.; Melanson, M.; Chamberlain, B. T.; Alper, S. L.; Santos, J.; Gutierrez, J.; Subramanian, A.; Grinkevich, E.; Bricio, E. R.; Kim, C.; Clark, A.; Watts, A.; Thompson, R.; Marshall, J.; Pablo, J. L.; Coraor, J.; Roignot, J.; Vernon, K. A.; Keller, K.; Campbell, A.; Emani, M.; Racette, M.; Bazua-Valenti, S.; Padovano, V.; Weins, A.; McAdoo, S. P.; Tam, F. W. K.; Ronco, L.; Wagner, F.; Tsokos, G. C.; Shaw, J. L.; Greka, A.
10.1101/2020.06.30.180380 — cell biology — Posted on 2020-06-30
51 Structure of the full SARS-CoV-2 RNA genome in infected cells
Lan, T. C. T.; Allan, M. F.; Malsick, L.; Khandwala, S.; Nyeo, S. S. Y.; Bathe, M.; Griffiths, A.; Rouskin, S.
10.1101/2020.06.29.178343 — biochemistry — Posted on 2020-06-30
52 SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
Huang, J.; Hume, A. J.; Abo, K. M.; Werder, R. B.; Villacorta-Martin, C.; Alysandratos, K. D.; Beermann, M. L.; Simone-Roach, C.; Olejnik, J.; Suder, E.; Bullitt, E.; Hinds, A.; Sharma, A.; Bosmann, M.; Wang, R.; Hawkins, F.; Burks, E. J.; Saeed, M.; Wilson, A. A.; Mühlberger, E.; Kotton, D. N.
10.1101/2020.06.30.175695 — molecular biology — Posted on 2020-06-30
53 Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM
Xu, C.; Wang, Y.; Liu, C.; Zhang, C.; Han, W.; Hong, X.; Wang, Y.; Hong, Q.; Wang, S.; Zhao, Q.; Wang, Y.; Yang, Y.; Chen, K.; Zheng, W.; Kong, L.; Wang, F.; Zuo, Q.; Huang, Z.; Cong, Y.
10.1101/2020.06.30.177097 — molecular biology — Posted on 2020-06-30
54 Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V.; Mishra, S.; Sharma, R.; Agarwal, J.; Ghoshal, U.; Khanna, T.; Sharma, L. K.; Verma, S. K.; Tiwari, S.
10.1101/2020.06.30.172833 — microbiology — Posted on 2020-06-30
56 SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 elicits immunogenicity in baboons and protection in mice
Tian, J.-H.; Patel, N.; Haupt, R.; Zhou, H.; Weston, S.; Hammond, H.; Lague, J.; Portnoff, A. D.; Norton, J.; Guebre-Xabier, M.; Zhou, B.; Jacobson, K.; Maciejewski, S.; Khatoon, R.; Wisniewska, M.; Mottitt, W.; Kluepfel-Stahl, S.; Ekechukwu, B.; Papin, J.; Boddapati, S.; Wong, C. J.; Piedra, P. A.; Frieman, M. B.; Massare, M. J.; Fries, L.; Lovgren Bengtsson, K.; Stertman, L.; Ellingsworth, L. R.; Glenn, G.; Smith, G.
10.1101/2020.06.29.178509 — microbiology — Posted on 2020-06-30
57 A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies
Acharya, P.; Williams, W.; Henderson, R.; Janowska, K.; Manne, K.; Parks, R.; Deyton, M.; Sprenz, J.; Stalls, V.; Kopp, M.; Mansouri, K.; Edwards, R. J.; Meyerhoff, R.; Oguin, T.; Sempowski, G.; Saunders, K. O.; Haynes, B. F.
10.1101/2020.06.30.178897 — immunology — Posted on 2020-06-30
58 Genetic variants in TMPRSS2 and Structure of SARS-CoV-2 spike glycoprotein and TMPRSS2 complex
Vishnubhotla, R.; Vankadari, N.; Ketavarapu, V.; Amanchy, R.; Avanthi, S.; Bale, G.; Nageshwar Reddy, D.; Sasikala, M.
10.1101/2020.06.30.179663 — genetics — Posted on 2020-06-30
59 Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2
Mou, H.; Quinlan, B.; Peng, H.; Guo, Y.; Peng, S.; Zhang, L.; Davis-Gardner, M.; Gardner, M.; Voo, Z. X.; Bailey, C. C.; Alpert, M.; Rader, C.; Choe, H.; Farzan, M.
10.1101/2020.06.29.178459 — microbiology — Posted on 2020-06-30
60 Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs
Ren, L.; Wu, C.; Guo, L.; Yao, J.; Wang, C.; Xiao, Y.; Pisco, A. O.; Wu, Z.; Lei, X.; Liu, Y.; Shi, L.; Han, L.; Zhang, H.; Xiao, X.; Zhong, J.; Wu, H.; Li, M.; Quake, S. R.; Huang, Y.; Wang, J.; wang, j.
10.1101/2020.06.30.175778 — cell biology — Posted on 2020-06-30
61 A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection
Herrmann, A.; Maruyama, J.; Yue, C.; Lahtz, C.; Zhou, H.; Kerwin, L.; Guo, W.; Zhang, Y.; Soo Hoo, W.; Yei, S.; Kwon, S.; Fu, Y.; Johnson, S.; Ledesma, A.; Zhuang, Y.; Zhuang, Y.; Yei, E.; Adamus, T.; Praessler, S.; Ji, H.
10.1101/2020.06.29.178616 — microbiology — Posted on 2020-06-30
62 Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera
Pape, C.; Remme, R.; Wolny, A.; Olberg, S.; Wolf, S.; Cerrone, L.; Cortese, M.; Klaus, S.; Lucic, B.; Ullrich, S.; Anders-Össwein, M.; Wolf, S.; Berati, C.; Neufeldt, C. J.; Ganter, M.; Schnitzler, P.; Merle, U.; Lusic, M.; Boulant, S.; Stanifer, M.; Bartenschlager, R.; Hamprecht, F. A.; Kreshuk, A.; Tischer, C.; Kräusslich, H.-G.; Müller, B.; Laketa, V.
10.1101/2020.06.15.152587 — microbiology — Posted on 2020-06-30
63 No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
van Dorp, L.; Richard, D.; Tan, C. C.; Shaw, L. P.; Acman, M.; Balloux, F.
10.1101/2020.05.21.108506 — genomics — Posted on 2020-06-30
65 The effect of delayed processing on ovarian tissue stored for fertility preservation
Zemyarska, M. S.; Bjarkadottir, B. D.; Wei, X.; Walker, C. A.; Lane, S. M.; Davies, J.; Williams, S. A.
10.1101/2020.06.30.180190 — physiology — Posted on 2020-06-30
67 The genetic architecture of structural left-right asymmetry of the human brain
Sha, Z.; Schijven, D.; Carrion-Castillo, A.; Joliot, M.; Mazoyer, B.; Fisher, S.; Crivello, F.; Francks, C.
10.1101/2020.06.30.179721 — neuroscience — Posted on 2020-06-30
68 Homozygote loss-of-function variants in the human COCH gene underlie hearing loss
Danial-Faran, N.; Chervinsky, E.; Nadar-Ponniah, P. T.; Cohen Barak, E.; Taiber, S.; Khayat, M.; Avraham, K. B.; Shalev, S. A.
10.1101/2020.06.29.178053 — genetics — Posted on 2020-06-30
70 Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques
Williams, W. B.; Meyerhoff, R.; Edwards, R. J.; Li, H.; Nicely, N.; Henderson, R.; Zhou, Y.; Janowska, K.; Mansouri, K.; Manne, K.; Stalls, V.; Hsu, A. L.; Borgnia, M. J.; Stewart-Jones, G.; Lee, M. S.; Bronkema, N.; Perfect, J.; Moody, A.; Wiehe, K.; Bradley, T.; Kepler, T. B.; Alam, M.; Parks, R. J.; Foulger, A.; Bonsignori, M.; LaBranche, C. C.; Montefiori, D. C.; Seaman, M.; Santra, S.; Francica, J. R.; Lynn, G. M.; Aussedat, B.; Walkowicz, W. E.; Laga, R.; Kelsoe, G.; Saunders, K. O.; Fera, D.; Kwong, P. D.; Seder, R. A.; Bartesaghi, A.; Shaw, G. M.; Acharya, P.; Haynes, B. F.
10.1101/2020.06.30.178921 — immunology — Posted on 2020-06-30
72 An All-to-All Approach to the Identification of Sequence-Specific Readers for Epigenetic DNA Modifications on Cytosine
Song, G.; Wang, G.; Luo, X.; Cheng, Y.; Song, Q.; Wan, J.; Moore, C.; Song, H.; Jin, P.; Qian, J.; Zhu, H.
10.1101/638700 — systems biology — Posted on 2020-06-30
73 Dynamic community detection reveals transient reorganization of functional brain networks across a female menstrual cycle
Mueller, J. M.; Pritschet, L.; Santander, T.; Taylor, C. M.; Grafton, S. T.; Jacobs, E. G.; Carlson, J. M.
10.1101/2020.06.29.178152 — neuroscience — Posted on 2020-06-30
74 Decoding spontaneous pain from brain cellular calcium signals using deep learning
Yoon, H.; BAK, M. S.; KIM, S. H.; LEE, J. H.; CHUNG, G.; KIM, S. J.; KIM, S. K.
10.1101/2020.06.30.179374 — neuroscience — Posted on 2020-06-30
75 Multi-epitope vaccine design using an immunoinformatics approach for 2019 novel coronavirus (SARS-CoV-2)
Feng, Y.; Qiu, M.; Liu, L.; Zou, S.; Li, Y.; Luo, K.; Guo, Q.; Han, N.; Sun, Y.; Wang, K.; Zhuang, X.; Zhang, S.; Chen, S.; Mo, F.
10.1101/2020.03.03.962332 — bioinformatics — Posted on 2020-06-30
77 Multi-Tissue Neocortical Transcriptome-Wide Associations Study Implicates 8 Genes Across 6 Genomic Loci in Alzheimer's Disease
Gockley, J.; Montgomery, K. S.; Poehlman, W. L.; Wiley, J. C.; Liu, Y.; gerasimov, e.; Greenwood, A. K.; Sieberts, S. K.; Wingo, A. P.; Wingo, T. S.; Mangravite, L. M.; Logsdon, B. A.
10.1101/2020.06.29.178590 — genomics — Posted on 2020-06-30
79 Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins
Zhang, Y.; Zhao, W.; Mao, Y.; Chen, Y.; Wang, S.; Zhong, Y.; Su, T.; Gong, M.; Du, D.; Lu, X.; Cheng, J.; Yang, H.
10.1101/2020.03.28.013276 — biochemistry — Posted on 2020-06-30
81 The transcription factor Pdr802 regulates Cryptococcus neoformans Titan cell production and pathogenicity
Reuwsaat, J. C. V.; Motta, H.; Agustinho, D. P.; Brown, H.; Chang, A. L.; Kmetzsch, L.; Doering, T. L.
10.1101/2020.06.29.179242 — microbiology — Posted on 2020-06-30
83 Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain
Werner, J. M.; Negesse, M. Y.; Brooks, D. L.; Caldwell, A. R.; Johnson, J. M.; Brewster, R.
10.1101/738161 — developmental biology — Posted on 2020-06-30
84 FastSK: Fast Sequence Analysis with Gapped String Kernels
Blakely, D.; Collins, E.; Singh, R.; Norton, A. P.; Lanchantin, J.; Qi, Y.
10.1101/2020.04.21.053975 — bioinformatics — Posted on 2020-06-30
86 Invasion and maintenance of spore killers in populations of ascomycete fungi
martinossi, i.; Veller, C.; Ament-Velasquez, S. L.; Vogan, A.; Rueffler, C.; Johannesson, H.
10.1101/2020.04.06.026989 — evolutionary biology — Posted on 2020-06-30
87 MetaboShiny - interactive processing, analysis and annotation of direct infusion metabolomics data
Wolthuis, J. C.; Magnusdottir, S.; Pras-Raves, M.; Moshiri, M.; Jans, J. J. M.; Burgering, B. M. T.; van Mil, S.; de Ridder, J.
10.1101/734236 — bioinformatics — Posted on 2020-06-30
88 Most-probable number based minimum duration of killing assay for determining the spectrum of rifampicin susceptibility in clinical M. tuberculosis isolates
Vijay, S.; Nhung, H. N.; Bao, N. L. H.; Thu, D. D. A.; Trieu, L. P. T.; Phu, N. H.; Thwaites, G.; Javid, B.; Thuong, N. T. T.
10.1101/2020.06.29.179200 — microbiology — Posted on 2020-06-30
89 Centromere evolution in the fungal genus Verticillium
Seidl, M.; Kramer, M.; Cook, D.; Lorencini Fiorin, G.; van den Berg, G.; Faino, L.; PHJ Thomma, B.
10.1101/2020.06.29.179234 — genetics — Posted on 2020-06-30
91 Exploring the understudied human kinome for research and therapeutic opportunities
The NIH Understudied Kinome Consortium, ; Moret, N.; Liu, C.; Gyori, B. M.; Bachman, J. A.; Steppi, A.; Taujale, R.; Huang, L.-C.; Hug, C.; Berginski, M.; Gomez, S. M.; Kannan, N.; Sorger, P.
10.1101/2020.04.02.022277 — systems biology — Posted on 2020-06-30
94 Mapping extinction risk in the global functional spectra across the tree of life
Carmona, C. P.; Tamme, R.; Partel, M.; de Bello, F.; Brosse, S.; Capdevila, P.; Gonzalez-M, R.; Gonzalez-Suarez, M.; Salguero-Gomez, R.; Vasquez-Valderrama, M.; Toussaint, A.
10.1101/2020.06.29.179143 — ecology — Posted on 2020-06-30
96 Emergence of Zika virus: Role of founder effects, drift and mutational reversions in spread to the Americas
Liu, J.; Liu, Y.; Shan, C.; Nunes, B. T. D.; Yun, R.; Haller, S. L.; Rafael, G. H.; Azar, S. R.; Andersen, C. R.; Plante, K. S.; Vasilakis, N.; Shi, P.-Y.; Weaver, S. C.
10.1101/2020.06.29.179150 — microbiology — Posted on 2020-06-30
97 Klebsiella pneumoniae reduces SUMOylation to limit host defence responses
Sa-Pessoa, J.; Przybyszewska, K.; Vasconcelos, F. N.; Dumigan, A.; Frank, C. G.; Hobley, L.; Bengoechea, J. A.
10.1101/2020.06.29.179275 — microbiology — Posted on 2020-06-30
100 Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage
Colombo, S.; Petit, V.; Wagner, R. Y.; Champeval, D.; Yajima, I.; Gesbert, F.; Davidson, I.; Delmas, V.; Larue, L.
10.1101/2020.06.29.179291 — developmental biology — Posted on 2020-06-30
101 Trans-scale-scope to find rare cellular activity in sub-million cells
Ichimura, T.; Kakizuka, T.; Horikawa, K.; Seiriki, K.; Kasai, A.; Hashimoto, H.; Fujita, K.; Watanabe, T. M.; Nagai, T.
10.1101/2020.06.29.179044 — cell biology — Posted on 2020-06-30
102 Membrane pore energetics and the pathways to membrane rupture
An, D.; Thiyagarajan, S.; Antipov, E.; Alcott, B. E.; O'Shaughnessy, B.
10.1101/2020.06.29.178988 — biophysics — Posted on 2020-06-30
103 Perturbation robustness analyses reveal important parameters in variant interpretation pipelines
Wang, Y.; Adhikari, A. N.; Sunderam, U.; Kvale, M. N.; Currier, R. J.; Gallagher, R. C.; Kwok, P.-Y.; Puck, J. M.; Srinivasan, R.; Brenner, S. E.
10.1101/2020.06.29.173815 — bioinformatics — Posted on 2020-06-30
104 Integrated glycoproteomics identifies a role of N-glycosylation and galectin-1 on myogenesis and muscle development
Blazev, R.; Ashwood, C.; Abrahams, J. L.; Chung, L. H.; Francis, D.; Yang, P.; Watt, K. I.; Qian, H.; Quaife-Ryan, G. A.; Hudson, J. E.; Gregorevic, P.; Thaysen-Andersen, M.; Parker, B. L.
10.1101/2020.06.29.178772 — biochemistry — Posted on 2020-06-30
105 Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity
Hynes, T.; Hrelja, K.; Hathaway, B.; Hounjet, C.; Chernoff, C.; Ebsary, S.; Betts, G.; Russell, B.; Ma, L.; Kaur, S.; Winstanley, C.
10.1101/2020.06.29.179069 — animal behavior and cognition — Posted on 2020-06-30
109 A single cell Arabidopsis root atlas reveals developmental trajectories in wild type and cell identity mutants
Shahan, R.; Hsu, C.-W.; Nolan, T. M.; Cole, B. J.; Taylor, I. W.; Vlot, A. H. C.; Benfey, P. N.; Ohler, U.
10.1101/2020.06.29.178863 — plant biology — Posted on 2020-06-30
115 The transcriptome of Balamuthia mandrillaris trophozoites for structure-based drug design
Phan, I. Q.; Rice, C. A.; Craig, J.; Noorai, R. E.; McDonald, J.; Subramanian, S.; Tillery, L.; Barrett, L. K.; Shankar, V.; Morris, J. C.; Van Voorhis, W. C.; Kyle, D. E.; Myler, P. J.
10.1101/2020.06.29.178905 — genomics — Posted on 2020-06-30
120 CoRINs: A tool to compare residue interaction networks from homologous proteins and conformers
Fonseca, F. V. d.; Souza Junior, R. O.; Soares, T. D.; de Almeida, M. V. A.; Morais, D. A. d. A.; Dalmolin, R. J. S.; Lima, J. P. M. S.
10.1101/2020.06.29.178541 — bioinformatics — Posted on 2020-06-30
126 Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation
Henderson, R.; Edwards, R. J.; Mansouri, K.; Janowska, K.; Stalls, V.; Kopp, M.; Haynes, B. F.; Acharya, P.
10.1101/2020.06.26.173765 — biophysics — Posted on 2020-06-30
129 Modeling the hemodynamic response function using motor task and eyes-open resting-state EEG-fMRI
Prokopiou, P. C.; Xifra-Porxas, A.; Kassinopoulos, M.; Boudrias, M.-H.; Mitsis, G. D.
10.1101/2020.06.29.178483 — neuroscience — Posted on 2020-06-30
132 Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing
McCartney, D. L.; Min, J. L.; Richmond, R. C.; Lu, A. T.; Sobczyk, M. K.; Davies, G.; Broer, L.; Guo, X.; Jeong, A.; Jung, J.; Kasela, S.; Katrinli, S.; Kuo, P.-L.; Matias-Garcia, P. R.; Mishra, P. P.; Nygaard, M.; Palviainen, T.; Patki, A.; Raffield, L. M.; Ratliff, S. M.; Richardson, T.; Robinson, O.; Soerensen, M.; Sun, D.; Tsai, P.-C.; van der Zee, M. D.; Walker, R. M.; Wang, X.; Wang, Y.; Xia, R.; Xu, Z.; Yao, J.; Zhao, W.; Correa, A.; Boerwinkle, E.; Dugue, P.-A.; Durda, P.; Elliott, H. R.; Gieger, C.; The Genetics of DNA Methylation Consortium (GoDMC), ; de Geus, E. J.; Harris, S. E.;
10.1101/2020.06.29.133702 — genetics — Posted on 2020-06-30
134 Feature Frequency Profile-based phylogenies are inaccurate
Li, Y.; David, K. T.; Shen, X.-X.; Steenwyk, J. L.; Halanych, K. M.; Rokas, A.
10.1101/2020.06.28.176479 — evolutionary biology — Posted on 2020-06-30
135 Multiple evolutionary pathways to achieve thermal adaptation in small mammals
Colella, J. P.; Tigano, A.; Dudchenko, O.; Omr, A. D.; Khan, R.; Bochkov, I. D.; Aiden, E. L.; MacManes, M. D.
10.1101/2020.06.29.178392 — evolutionary biology — Posted on 2020-06-30
137 Fungi.guru: comparative genomic and transcriptomic database for the Fungi kingdom
Lim, J. J. J.; Koh, J.; Moo, J. R.; Villanueva, E. M. F.; Putri, D. A.; Lim, Y. S.; Seetoh, W. S.; Mulupuri, S.; Ng, J. W. Z.; Nguyen, N. L. U.; Reji, R.; Zhao, M. X.; Chan, T. L.; Rodrigues, E. E.; Kairon, R.; Chee, N. C.; Low, A. D.; Xin, Z. C. H.; Lim, S. C.; Lunardi, V.; Choy, F. T.; Chua, C. X.; Sween, K. K. T.; Ng, J. W. X.; Mutwil, M.
10.1101/2020.06.26.174581 — bioinformatics — Posted on 2020-06-30
143 FUNGAL DYSBIOSIS CORRELATES WITH THE DEVELOPMENT OF TUMOUR-INDUCED CACHEXIA IN MICE
Jabes, D. L.; de Maria, Y. Y. N. L. F.; Aciole Barbosa, D.; Santos, K. B. N. H.; Alencar, V. C.; Carvalho, L. M.; Humberto, A. C.; Batista, M. M. L.; Costa de Oliveira, R.; Menegidio, F. B.; Nunes, L. R.
10.1101/2020.06.29.171397 — microbiology — Posted on 2020-06-30
145 Citizen Scientists Create an Exascale Computer to Combat COVID-19
Zimmerman, M. I.; Porter, J. R.; Ward, M. D.; Singh, S.; Vithani, N.; Meller, A.; Mallimadugula, U. L.; Kuhn, C. E.; Borowsky, J. H.; Wiewiora, R. P.; Hurley, M. F. D.; Harbison, A. M.; Fogarty, C. A.; Coffland, J. E.; Fadda, E.; Voelz, V. A.; Chodera, J. D.; Bowman, G. R.
10.1101/2020.06.27.175430 — biophysics — Posted on 2020-06-30
146 Deglutarylation of GCDH by SIRT5 controls lysine metabolism in mice
Bhatt, D. P.; Mills, C. A.; Anderson, K. A.; Henriques, B. J.; Lucas, T. G.; Francisco, S.; Liu, J.; Ilkayeva, O. R.; Adams, A. E.; Kulkarni, S. R.; Backos, D. S.; Grimsrud, P. A.; Gomes, C. M.; Hirschey, M. D.
10.1101/2020.06.28.176677 — biochemistry — Posted on 2020-06-30
147 Discovery of a Cellular Mechanism Regulating Transcriptional Noise
Desai, R.; Hansen, M. M. K.; Martin, B.; Yu, C.; Ding, S.; Thomson, M.; Weinberger, L. S.
10.1101/2020.06.29.128439 — systems biology — Posted on 2020-06-30
149 Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis
Ruiz-Ojeda, F. J.; Wang, J.; Baecker, T.; Krueger, M.; Zamani, S.; Rosowski, S.; Gruber, T.; Feuchtinger, A.; Schulz, T. J.; Faessler, R.; Müller, T. D.; Garcia-Caceres, C.; Meier, M.; Mathias, B.; Ussar, S.
10.1101/2020.06.29.178020 — physiology — Posted on 2020-06-30
151 Effect of ligands on HP-induced unfolding and oligomerization of β-lactoglobulin
Combet, S.; Minic, S.; Annighöfer, B.; Helary, A.; Hamdane, D.; Hui Bon Hoa, G.; Loupiac, C.; Brulet, A.
10.1101/2020.06.29.177972 — biophysics — Posted on 2020-06-30
155 ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways
Treveil, A.; Bohar, B.; Sudhakar, P.; Gul, L.; Csabai, L.; Olbei, M.; Poletti, M.; Madgwick, M.; Andrighetti, T.; Hautefort, I.; Modos, D.; Korcsmaros, T.
10.1101/2020.06.23.167254 — systems biology — Posted on 2020-06-30
159 Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase
Chen, Z.; Zhang, J.; Heilig, R.; Sorrell, F. J.; D'Angiolella, V.; Fischer, R.; Alessi, D. R.; Bullock, A. N.
10.1101/2020.06.29.178285 — molecular biology — Posted on 2020-06-29
162 Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells
Carlin, E.; Greer, B.; Duverger, A.; Wagner, F.; Moylan, D.; Dalecki, A.; Samuel, S.; Perez, M.; Lowman, K.; Sabbaj, S.; Kutsch, O.
10.1101/2020.06.29.177394 — microbiology — Posted on 2020-06-30
163 Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of purine nucleotide cycle driven fumarate accumulation
Sinton, M. C.; Lucendo Villarin, B.; Meseguer Ripolles, J.; Wernig-Zorc, S.; Thomson, J. P.; Walker, P. D.; Thakker, A.; Lavery, G. G.; Ludwig, C.; Tennant, D. A.; Hay, D. C.; Drake, A. J.
10.1101/2020.06.23.166728 — biochemistry — Posted on 2020-06-29
164 Unique actions of GABA arising from cytoplasmic chloride microdomains
Rahmati, N.; Normoyle, K. P.; Glykys, J.; Dzhala, V. I.; Lillis, K. P.; Kahle, K. T.; Raiyyani, R.; Jacob, T.; Staley, K. J.
10.1101/2020.06.29.178160 — neuroscience — Posted on 2020-06-29
170 Meiosis reveals the early steps in the evolution of a neo-XY sex chromosome pair in the African pygmy mouse Mus minutoides
Gil-Fernandez, A.; Saunders, P.; Martin-Ruiz, M.; Ribagorda, M.; Lopez-Jimenez, P.; Jeffries, D. L.; Parra, M. T.; Viera, A.; Rufas, J. S.; Perrin, N.; Veyrunes, F.; Page, J.
10.1101/2020.06.29.177329 — genetics — Posted on 2020-06-29
171 Swarm Learning as a privacy-preserving machine learning approach for disease classification
Warnat-Herresthal, S.; Schultze, H.; Shastry, K. P. L.; Manamohan, S.; Mukherjee, S.; Garg, V.; Sarveswara, R.; Haendler, K.; Pickkers, P.; Aziz, N. A.; Ktena, S.; Siever, C.; Kraut, M.; Desai, M.; Monet, B.; Saridaki, M.; Siegel, C. M.; Drews, A.; Nuesch-Germano, M.; Theis, H.; Netea, M. G.; Theis, F. J.; Aschenbrenner, A. C.; Ulas, T.; Breteler, M. M. B.; Giamarellos-Bourboulis, E. J.; Kox, M.; Becker, M.; Cheran, S.; Woodacre, M. S.; Goh, E. L.; Schultze, J. L.; German COVID-19 OMICS Initiative (DeCOI),
10.1101/2020.06.25.171009 — bioinformatics — Posted on 2020-06-29
172 Differential role of cytosolic Hsp70s in longevity assurance and protein quality control
Andersson, R.; Eisele-Bürger, A. M.; Hanzen, S.; Vielfort, K.; Öling, D.; Eisele, F.; Johansson, G.; Gustafsson, T.; Kvint, K.; Nyström, T.
10.1101/2020.06.25.170670 — molecular biology — Posted on 2020-06-29
174 μ-Lat: A High-Throughput Humanized Mouse Model to Evaluate Human Immunodeficiency Virus Eradication Strategies
Sperber, H. S.; Togarrati, P. P.; Raymond, K. A.; Bouzidi, M. S.; Gilfanova, R.; Gutierrez, A. G.; Muench, M. O.; Pillai, S. K.
10.1101/2020.02.18.955492 — microbiology — Posted on 2020-06-29
181 Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma
Ramiro, A. R.; Delgado, P.; Alvarez-Prado, A.; Marina-Zarate, E.; Sernandez, I.; Mur, S. M.; de la Barrera, J.; Sanchez-Cabo, F.; Canamero, M.; de Molina, A.; Belver, L.; de Yebenes, V. G.
10.1101/2020.06.29.177303 — cancer biology — Posted on 2020-06-29
183 Nanotrap(R) particles improve detection of SARS-CoV-2 for pooled sample methods, extraction-free saliva methods, and extraction-free medium methods
Barclay, R. A.; Akhrymuk, I.; Patnaik, A.; Callahan, V.; Lehman, C.; Andersen, P.; Barbero, R.; Barksdale, S.; Dunlap, R.; Goldfarb, D.; Jones-Roe, T.; Kelly, R.; Kim, B.; Miao, S.; Munns, A.; Munns, D.; Patel, S.; Porter, E.; Ramsey, R.; Sahoo, S.; Swahn, O.; Warsh, J.; Kehn-Hall, K.; Lepene, B.
10.1101/2020.06.25.172510 — microbiology — Posted on 2020-06-29
188 In situ humoral selection in human lupus tubulointerstitial inflammation
Kinloch, A. J.; Asano, Y.; Mohsin, A.; Henry, C. J.; Abraham, R.; Chang, A.; Labno, C.; Wilson, P. C.; Clark, M. R.
10.1101/2020.06.29.178145 — immunology — Posted on 2020-06-29
190 Structural and molecular determinants of CCS-mediated copper activation of MEK1/2
Grasso, M.; Bond, G. J.; Kim, Y.-J.; Alwan, K. B.; Boyd, S.; Dzebo, M. M.; Valenzuela, S.; Tsang, T.; Schibrowsky, N. A.; Matthews, M. L.; Burslem, G. M.; Wittung-Stafshede, P.; Winkler, D. D.; Blackburn, N. J.; Marmorstein, R.; Brady, D. C.
10.1101/2020.05.01.072124 — biochemistry — Posted on 2020-06-29
191 First responders shape a prompt and sharp NF-κB-mediated transcriptional response to TNF-α
Zambrano, S.; Loffreda, A.; Carelli, E.; Stefanelli, G.; Colombo, F.; Bertrand, E.; Tacchetti, C.; Agresti, A.; Bianchi, M. E.; Molina, N.; Mazza, D.
10.1101/2020.06.27.174995 — systems biology — Posted on 2020-06-29
192 Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice
Brito, D. V.; Gulmez Karaca, K.; Kupke, J.; Mudlaff, F.; Zeuch, B.; Gomes, R.; Lopes, L. V.; Oliveira, A. M. M.
10.1101/2020.01.12.903112 — neuroscience — Posted on 2020-06-29
194 Ultra-deep sequencing differentiates patterns of skin clonal mutations associated with sun-exposure status and skin cancer burden
Wei, L.; Christensen, S.; Fitzgerald, M.; Graham, J.; Hutson, N.; Zhang, C.; Huang, Z.; Hu, Q.; Zhan, F.; Xie, J.; Zhang, J.; Liu, S.; Remenyik, E.; Gellen, E.; Colegio, O. R.; Bax, M.; Xu, J.; Lin, H.; Huss, W. J.; Foster, B. A.; Paragh, G.
10.1101/2020.01.10.902098 — cancer biology — Posted on 2020-06-29
195 mTOR-driven widespread exon skipping renders multifaceted gene regulation and proteome complexity
Cheng, S.; Fahmi, N. A.; Park, M.; Chang, J.-W.; Sun, J.; Thao, K.; Yeh, H.-S.; Zhang, W.; Yong, J.
10.1101/2020.02.27.967737 — biochemistry — Posted on 2020-06-29
196 Flexible coordinator and switcher hubs for adaptive task control
Cocuzza, C. V.; Ito, T.; Schultz, D. H.; Bassett, D. S.; Cole, M. W.
10.1101/822213 — neuroscience — Posted on 2020-06-29
197 Shared Neural Representations of Cognitive Conflict and Negative Affect in the Medial Frontal Cortex
Vermeylen, L.; Wisniewski, D.; Gonzalez-Garcia, C.; Hoofs, V.; Notebaert, W.; Braem, S.
10.1101/824839 — neuroscience — Posted on 2020-06-29
200 Progesterone shapes medial temporal lobe volume across the human menstrual cycle
Taylor, C. M.; Pritschet, L.; Olsen, R.; Layher, E.; Santander, T.; Grafton, S. T.; Jacobs, E. G.
10.1101/2020.02.04.934141 — neuroscience — Posted on 2020-06-29
203 Dynamic changes in large-scale functional connectivity predict performance in a multisensory task
Hollensteiner, K. J.; Galindo-Leon, E.; Pieper, F.; Engler, G.; Nolte, G.; Engel, A. K.
10.1101/579938 — neuroscience — Posted on 2020-06-29
204 Pan-transcriptome-based Candidate Therapeutic Discovery for Idiopathic Pulmonary Fibrosis
Wang, Y.; Yella, J. K.; Ghandikota, S.; Cherukuri, T. C.; Ediga, H. H.; Madala, S. K.; Jegga, A. G.
10.1101/824367 — genomics — Posted on 2020-06-29
206 A multi-omic integrative scheme characterizes tissues of action at loci associated with type 2 diabetes
Torres, J. M.; Abdalla, M.; Payne, A.; Fernandez-Tajes, J.; Thurner, M.; Nylander, V.; Gloyn, A. L.; Mahajan, A.; McCarthy, M. I.
10.1101/2020.06.25.169706 — genetics — Posted on 2020-06-29
207 Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations
Kar, S. P.; Lindstroem, S.; Hung, R.; Lawrenson, K.; Schmidt, M.; O'Mara, T.; Glubb, D.; Tyrer, J.; Schildkraut, J.; Chang-Claude, J.; Alsulimani, A.; Anton, F.; Beeghly-Fadiel, A.; Bjorge, L.; Bodelon, C.; Brauch, H.; Burghaus, S.; Campa, D.; Carney, M.; Chen, C.; Chen, Z.; Daly, M.; du Bois, A.; Ekici, A.; Ewing, A.; Fasching, P.; Flanagan, J. M.; Gawelko, J.; Giles, G.; Hamilton, R.; Harris, H.; Heitz, F.; Hildebrandt, M.; Hillemanns, P.; Huang, R.-Y.; Imaz, L.; Irmejs, A.; Jakubowska, A.; Jensen, A.; John, E.; Kannisto, P.; Karlan, B.; Khusnutdinova, E.; Kiemeney, L.; Kjaer, S.; Klapdor, R
10.1101/2020.06.16.146803 — genetics — Posted on 2020-06-29
208 Forest decline differentially affects trophic guilds of canopy-dwelling beetles
Salle, A.; Parmain, G.; Nusillard, B.; Pineau, X.; Brousse, R.; Fontaine-Guenel, T.; Ledet, R.; Vincent-Barbaroux, C.; Bouget, C.
10.1101/2020.02.11.943753 — ecology — Posted on 2020-06-29
209 Valproic Acid-Induced Changes of 4D Nuclear Morphology in Astrocyte Cells
Kalinin, A. A.; Hou, X.; Ade, A. S.; Fon, G.-V.; Meixner, W.; Higgins, G. A.; Sexton, J. Z.; Wan, X.; Dinov, I. D.; Athey, B. D.
10.1101/2020.06.29.178202 — bioinformatics — Posted on 2020-06-29
210 Evolution of the DAN gene family in vertebrates
Opazo, J. C.; Hoffmann, F. G.; Zavala, K.; Edwards, S. V.
10.1101/794404 — evolutionary biology — Posted on 2020-06-29
213 Baclofen decreases compulsive alcohol drinking in rats characterised by reduced levels of GAT-3 in the central amygdala
Marti-Prats, L.; Belin-Rauscent, A.; Fouyssac, M.; Puaud, M.; Cocker, P. J.; Everitt, B. J.; Belin, D.
10.1101/2020.06.29.178236 — neuroscience — Posted on 2020-06-29
214 Nucleus accumbens melanin-concentrating hormone signaling promotes feeding in a sex-specific manner
Terrill, S. J.; Subramanian, K.; Lan, R.; Liu, C. M.; Cortella, A. M.; Noble, E. E.; Kanoski, S. E.
10.1101/2020.06.16.155747 — neuroscience — Posted on 2020-06-29
216 Mutations in the SPTLC1 gene are a cause of juvenile amyotrophic lateral sclerosis that may be amenable to serine supplementation
Johnson, J. O.; Chia, R.; Miller, D. E.; Li, R.; Abramzon, Y.; Kumaran, R.; Alahmady, N.; Faghri, F.; Renton, A. E.; Topp, S. D.; Pliner, H. A.; Gibbs, J. R.; Ding, J.; Smith, N.; Landeck, N.; Nalls, M. A.; Cookson, M. R.; Pletnikova, O.; Troncoso, J.; Scholz, S. W.; Sabir, M. S.; Ahmed, S.; Dalgard, C. L.; Troakes, C.; Jones, A. R.; Shatunov, A.; Iacoangeli, A.; Al Khleifat, A.; Ticozzi, N.; Silani, V.; Gellera, C.; Blair, I. P.; Dobson-Stone, C.; Kwok, J. B.; England, B. K.; Bonkowski, E. S.; The International ALS Genomics Consortium, ; The ITALSGEN Consortium, ; The FALS Sequencing Consor
10.1101/770339 — genetics — Posted on 2020-06-29
217 K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15
Begley, M. A.; Solon, A. L.; Davis, E. M.; Sherrill, M. G.; Ohi, R.; Elting, M. W.
10.1101/2020.05.19.104661 — cell biology — Posted on 2020-06-29
221 Structural basis of envelope and phase intrinsic coupling modes of the cerebral cortex
Messe, A.; Hollensteiner, K. J.; Delettre, C.; Dell, L.-A.; Pieper, F.; Nentwig, L. J.; Galindo-Leon, E. E.; Larrat, B.; Meriaux, S.; Mangin, J.-F.; Reillo, I.; de Juan Romero, C.; Borrell, V.; Engler, G.; Toro, R.; Engel, A. K.; Hilgetag, C. C.
10.1101/500009 — neuroscience — Posted on 2020-06-29
222 Maturation of cortical microstructure and cognitive development in childhood and adolescence: a T1w/T2w ratio MRI study
Norbom, L. B.; Rokicki, J.; Alnaes, D.; Kaufmann, T.; Doan, N. T.; Andreassen, O. A.; Westlye, L. T.; Tamnes, C. K.
10.1101/681221 — neuroscience — Posted on 2020-06-29
223 RING Finger Protein 11 (RNF11) modulates dopamine release in Drosophila
Privman Champaloux, E.; Donelson, N.; Pyakurel, P.; Wolin, D.; Ostendorf, L.; Denno, M.; Borman, R.; Burke, C.; Short-Miller, J. C.; Yoder, M. R.; Copeland, J. M.; Sanyal, S.; Venton, B. J.
10.1101/2020.06.29.177857 — neuroscience — Posted on 2020-06-29
224 Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states
Girbig, M.; Misiaszek, A. D.; Vorländer, M. K.; Lafita, A.; Grötsch, H.; Baudin, F.; Bateman, A.; Müller, C. W.
10.1101/2020.06.29.177642 — molecular biology — Posted on 2020-06-29
225 A universal RT-qPCR assay for "One Health" detection of influenza A viruses
Nagy, A.; Cernikova, L.; Kunteova, K.; Dirbakova, Z.; Thomas, S. S.; Slomka, M. J.; Dan, A.; Varga, T.; Mate, M.; Jirincova, H.; Brown, I. H.
10.1101/2020.06.29.171306 — microbiology — Posted on 2020-06-29
227 Identification of a novel missense variant in SPDL1 associated with idiopathic pulmonary fibrosis
Dhindsa, R. S.; Mattsson, J.; Nag, A.; Wang, Q.; Wain, L. V.; Allen, R.; Wigmore, E. M.; Ibanez, K.; Vitsios, D.; Deevi, S. V. V.; Wasilewski, S.; Karlsson, M.; Lassi, G.; Olsson, H.; Muthas, D.; Mackay, A.; Murray, L.; Young, S.; Haefliger, C.; FinnGen Consortium, ; Maher, T. M.; Belvisi, M. G.; Jenkins, G.; Molyneaux, P.; Platt, A.; Petrovski, S.
10.1101/2020.06.29.178079 — genetics — Posted on 2020-06-29
228 The diverging evolutionary history of opsin genes in Diptera
Feuda, R.; Goulty, M.; Zadra, N.; Gasparetti, T.; Rosato, E.; Segata, N.; Rizzoli, A.; Pisani, D.; Ometto, L.; Rota-Stabelli, O.
10.1101/2020.06.29.177931 — evolutionary biology — Posted on 2020-06-29
229 The cryptic plastid of Euglena longa defines a new type of non-photosynthetic plastid organelles
Füssy, Z.; Zahonova, K.; Tomcala, A.; Krajcovic, J.; Yurchenko, V.; Obornik, M.; Elias, M.
10.1101/765255 — evolutionary biology — Posted on 2020-06-29
230 HLF Expression Defines the Human Haematopoietic Stem Cell State
Lehnertz, B.; MacRae, T.; Chagraoui, J.; Tomellini, E.; Corneau, S.; Mayotte, N.; Boivin, I.; Sauvageau, G.
10.1101/2020.06.29.177709 — cell biology — Posted on 2020-06-29
234 Heh2/Man1 may be an evolutionarily conserved sensor of NPC assembly state
Lusk, C. P.; Borah, S.; Thaller, D. J.; Hakhverdyan, Z.; Rodriguez, E. C.; Rout, M. P.; King, M. C.
10.1101/2020.06.29.178129 — cell biology — Posted on 2020-06-29
235 Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy
Srivastava, S. P.; Zhou, H.; Setia, O.; Dardik, A.; Fernandez-Hernando, C.; Goodwin, J.
10.1101/2020.06.29.178228 — cell biology — Posted on 2020-06-29
236 Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas disease
Dean, D. A.; Gautham, ; Siqueira-Neto, J. L.; McKerrow, J. H.; Dorrestein, P. C.; McCall, L.-I.
10.1101/2020.06.29.178038 — biochemistry — Posted on 2020-06-29
237 Domain Binding and Isotype Dictate the Activity of Anti-human OX40 Antibodies
Griffiths, J.; Hussain, K.; Smith, H. L.; Sanders, T.; Cox, K.; Semmrich, M.; Martennson, L.; Kim, J.; Inzhelevskaya, T.; Penfold, C.; Tutt, A. L.; Mockridge, I.; Chan, C. H.; English, V.; French, R. R.; Teige, I.; Al-Shamkhani, A.; Glennie, M. J.; Frendeus, B.; Willoughby, J. E.; Cragg, M. S.
10.1101/2020.06.29.177691 — immunology — Posted on 2020-06-29
238 Comprehensive annotations of the mutational spectra of SARS-CoV-2 spike protein: a fast and accurate pipeline
Rahman, M. S.; Islam, M. R.; Hoque, M. N.; Alam, A. S. M. R. U.; Akther, M.; Puspo, J. A.; Akter, S.; Anwar, A.; Sultana, M.; Hossain, M. A.
10.1101/2020.06.29.177238 — evolutionary biology — Posted on 2020-06-29
240 An in vitro assessment of anti-SARS-CoV-2 activity of oral preparations of iodine complexes (RENESSANS)
Altaf, I.; Nadeem, M. F.; Hussain, N.; Nawaz, M.; Raza, S.; Ali, M. A.; Hasan, S.; Matti, N.; Ashraf, M.; Ullah, I.; Aziz, W.; Fazal, S.; Rafique, S.; Adnan, M.; Sardar, N.; Khan, T.; Moavia, M.; Ashraf, S.; Tahir, Z.; Mukhtar, N.; Yaqub, T.
10.1101/2020.06.29.171173 — microbiology — Posted on 2020-06-29
242 SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery
Mulay, A.; Konda, B.; Garcia, G.; Yao, C.; Beil, S.; Sen, C.; Purkayastha, A.; Kolls, J.; Pociask, D.; Pessina, P.; Garcia-de-Alba, C.; Sainz de Aja, J.; Kim, C.; Gomperts, B.; Arumugaswami, V.; Stripp, B.
10.1101/2020.06.29.174623 — cell biology — Posted on 2020-06-29
243 Phosphorylation modulates liquid-liquid phase separation of the SARS-CoV-2 N protein
Carlson, C. R.; Asfaha, J. B.; Ghent, C. M.; Howard, C. J.; Hartooni, N.; Morgan, D. O.
10.1101/2020.06.28.176248 — biochemistry — Posted on 2020-06-29
247 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damage and constitutes an antiviral target
Gao, Z.; Xia, B.; Shen, X.; He, Y.; Pan, X.; Wang, Y.; Yang, F.; Fang, S.; Wu, Y.; Zuo, X.; Xie, Z.; Jiang, X.; Chi, H.; Meng, Q.; Zhou, H.; Zhou, Y.; Cheng, X.; Cheng, T.; Xin, X.; Jiang, H.; Xiao, G.; Zhao, Q.; Zhang, L.-K.; Shen, J.; Li, J.
10.1101/2020.06.27.174953 — microbiology — Posted on 2020-06-29
252 Stereotypic Neutralizing VH Clonotypes Against SARS-CoV-2 RBD in COVID-19 Patients and the Healthy Population
Kim, S. I.; Noh, J.; Kim, S.; Choi, Y.; Yoo, D. K.; Lee, Y.; Lee, H.; Jung, J.; Kang, C. K.; Song, K.-H.; Choe, P. G.; Kim, H. B.; Kim, E. S.; Kim, N.-J.; Seong, M.-W.; Park, W. B.; Oh, M.-d.; Kwon, S.; Chung, J.
10.1101/2020.06.26.174557 — immunology — Posted on 2020-06-29
253 Nicotinic receptors atlas in the adult human lung
Diabasana, Z.; Perotin, J.-M.; Belgacemi, R.; Ancel, J.; Mulette, P.; Delepine, G.; Gosset, P.; Maskos, U.; Polette, M.; Deslee, G.; Dormoy, V.
10.1101/2020.06.29.176750 — cell biology — Posted on 2020-06-29
257 Whole-brain dynamics in aging: disruptions in functional connectivity and the role of the rich club
Escrichs, A.; Biarnes, C.; Garre-Olmo, J.; Fernandez-Real, J. M.; Ramos, R.; Pamplona, R.; Brugada, R.; Serena, J.; Ramio-Torrenta, L.; Coll-De-Tuero, G.; Gallart, L.; Barretina, J.; Vilanova, J. C.; Mayneris-Perxachs, J.; Essig, M.; Figley, C. R.; Pedraza, S.; Puig, J.; Deco, G.
10.1101/2020.06.29.164343 — neuroscience — Posted on 2020-06-29
258 DRAM for distilling microbial metabolism to automate the curation of microbiome function
Shaffer, M.; Borton, M. A.; McGivern, B. B.; Zayed, A. A.; L. La Rosa, S.; Solden, L. M.; Liu, P.; Narrowe, A. B.; Rodriguez-Ramos, J.; Bolduc, B.; Gazitua, M. C.; Daly, R. A.; Smith, G. J.; Vik, D. R.; Pope, P. B.; Sullivan, M. B.; Roux, S.; Wrighton, K. C.
10.1101/2020.06.29.177501 — microbiology — Posted on 2020-06-29
259 RNA Atlas of Human Bacterial Pathogens Uncovers Stress Dynamics Linked to Infection
Avican, K.; Aldahdooh, J.; Togninalli, M.; Tang, J.; Borgwardt, K. M.; Rhen, M.; Fallman, M.
10.1101/2020.06.29.177147 — microbiology — Posted on 2020-06-29
261 SARS-CoV-2 Spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity
Petruk, G.; Puthia, M.; Petrlova, J.; Strömdahl, A.-C.; Kjellström, S.; Schmidtchen, A.
10.1101/2020.06.29.175844 — immunology — Posted on 2020-06-29
264 The silencing factor Sir3 is a molecular bridge that sticks together distant loci
Ruault, M.; Scolari, V. F.; Lazar-Stefanita, L.; Hocher, A.; Loiodice, I.; Nous, C.; Koszul, R.; Taddei, A.
10.1101/2020.06.29.178368 — cell biology — Posted on 2020-06-29
269 Male-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant inducing premature aging and senescence
Walker, E. M.; Tong, X.; Cha, J.; Guo, M.; Liu, J.-H.; Yu, S.; Iacovazzo, D.; Mauvais-Jarvis, F. M.; Flanagan, S. E.; Korbonits, M.; Stafford, J.; Jacobson, D. A.; Stein, R.
10.1101/2020.06.29.177527 — molecular biology — Posted on 2020-06-29
270 Direct Quantification of in vivo Mutagenesis Using Duplex Sequencing
Valentine, C. C.; Young, R. R.; Fielden, M. R.; Kulkarni, R.; Williams, L. N.; Li, T.; Minocherhomji, S.; Salk, J. J.
10.1101/2020.06.28.176685 — genomics — Posted on 2020-06-29
271 Metal contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster
Gabriel, F. A.; Hauser-Davis, R. A.; Soares, L. O. S.; Mazzuco, A. C. d. A.; Rocha, R. C. C.; Saint Pierre, T. D.; Saggioro, E. M.; Correia, F. V.; Ferreira, T. O.; Bernardino, A. F.
10.1101/2020.06.29.177253 — ecology — Posted on 2020-06-29
275 Functional solubilisation of the β2-adrenoceptor (β2AR) using Diisobutylene maleic acid (DIBMA).
Harwood, C. R.; Sykes, D. A.; Hoare, B.; Heydenreich, F. M.; Uddin, R.; Poyner, D. R.; Briddon, S. J.; Veprintsev, D. B.
10.1101/2020.06.29.171512 — biochemistry — Posted on 2020-06-29
279 AutoSpill: a method for calculating spillover coefficients in high-parameter flow cytometry
Roca, C. P.; Burton, O. T.; Prezzemolo, T.; Whyte, C. E.; Halpert, R.; Kreft, Łukasz; Collier, J.; Botzki, A.; Spidlen, J.; Humblet-Baron, S.; Liston, A.
10.1101/2020.06.29.177196 — immunology — Posted on 2020-06-29
282 PRECISE+ predicts drug response in patients by non-linear subspace-based transfer from cell lines and PDX models
Mourragui, S.; Loog, M.; Vis, D. J.; Moore, K.; Manjon, A. G.; van de Wiel, M. A.; Reinders, M. J. T.; Wessels, L. F. A.
10.1101/2020.06.29.177139 — bioinformatics — Posted on 2020-06-29
283 Zonal human hepatocytes are differentially permissive to Plasmodium falciparum malaria parasites
Yang, A. S.-P.; van Waardenburg, Y. M.; van de Vegte-Bolmer, M.; van Gemert, G.-J. A.; Graumans, W.; de Wilt, H. H. W.; Sauerwein, R. W.
10.1101/2020.06.29.175968 — microbiology — Posted on 2020-06-29
285 Unbiased metabolic flux inference through combined thermodynamic and 13C flux analysis
Saldida, J.; Muntoni, A. P.; de Martino, D.; Hubmann, G.; Niebel, B.; Schmidt, A. M.; Braunstein, A.; Milias-Argeits, A.; Heinemann, M.
10.1101/2020.06.29.177063 — systems biology — Posted on 2020-06-29
291 GWAS reveals the genetic complexity of fructan accumulation patterns in barley grain
Matros, A.; Houston, K.; Tucker, M. R.; Schreiber, M.; Berger, B.; Aubert, M. K.; Wilkinson, L. G.; Witzel, K.; Waugh, R.; Seiffert, U.; Burton, R. A.
10.1101/2020.06.29.177881 — plant biology — Posted on 2020-06-29
292 The Filter Detection Task for measurement of breathing-related interoception and metacognition
Harrison, O. K.; Garfinkel, S. N.; Marlow, L.; Finnegan, S.; Marino, S.; Nanz, L.; Allen, M.; Finnemann, J.; Keur-Huizinga, L.; Harrison, S. J.; Stephan, K. E.; Pattinson, K. T.; Fleming, S. M.
10.1101/2020.06.29.176941 — neuroscience — Posted on 2020-06-29
293 Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
Sekine, T.; Perez-Potti, A.; Rivera-Ballesteros, O.; Straling, K.; Gorin, J.-B.; Olsson, A.; Llewellyn-Lacey, S.; Kamal, H.; Bogdanovic, G.; Muschiol, S.; Wulliman, D. J.; Kammann, T.; Emgard, J.; Parrot, T.; Folkesson, E.; Rooyackers, O.; Eriksson, L. I.; Sonnerborg, A.; Allander, T.; Albert, J.; Nielsen, M.; Klingstrom, J.; Gredmark-Russ, S.; Bjorkstrom, N. K.; Sandberg, J. K.; Price, D. A.; Ljunggren, H.-G.; Aleman, S.; Buggert, M.; Karolinska COVID-19 Study Group,
10.1101/2020.06.29.174888 — immunology — Posted on 2020-06-29
294 Genomic stability and adaptation of beer brewing yeasts during serial repitching in the brewery
Large, C. R. L.; Hanson, N. A.; Tsouris, A.; Abou Saada, O.; Koonthongkaew, J.; Toyokawa, Y.; Schmidlin, T.; Moreno-Habel, D. A.; McConnellogue, H.; Preiss, R.; Takagi, H.; Schacherer, J.; Dunham, M. J.
10.1101/2020.06.26.166157 — evolutionary biology — Posted on 2020-06-29
295 Shear flow-driven actin re-organization induces ICAM-1 nanoclustering on endothelial cells that impact T-cell migration
Piechocka, I.; Keary, S.; Sosa-Costa, A.; Lau, L.; Mohan, N.; Stanisavljevic, J.; Borgman, K.; Lakadamyali, M.; Manzo, C.; Garcia-Parajo, M. F.
10.1101/2020.06.29.177816 — cell biology — Posted on 2020-06-29
296 CoExp Web, a web tool for the exploitation of co-expression networks
Garcia, S.; Gil, A. L.; Cisterna, A.; Jurado, F.; Reynolds, R. H.; North America Brain Expression Consortium (NABEC), ; Cookson, M. R.; Hardy, J.; Ryten, M.; Botia, J. A.
10.1101/2020.06.29.176057 — bioinformatics — Posted on 2020-06-29
300 Cellular logics bringing the symmetry breaking in spiral nucleation revealed by trans-scale imaging
Kakizuka, T.; Hara, Y.; Ohta, Y.; Mukai, A.; Ichiraku, A.; Arai, Y.; Ichimura, T.; Takeharu, N.; Horikawa, K.
10.1101/2020.06.29.176891 — systems biology — Posted on 2020-06-29
308 Single molecule occupancy patterns of transcription factors reveal determinants of cooperative binding in vivo
Soenmezer, C.; Kleinendorst, R.; Imanci, D.; Villacorta, L.; Schuebeler, D.; Benes, V.; Krebs, A. R.
10.1101/2020.06.29.167155 — genomics — Posted on 2020-06-29
309 Mapping genetic effects on cellular phenotypes with "cell villages"
Mitchell, J. M.; Nemesh, J.; Ghosh, S.; Handsaker, R. E.; Mello, C.; Meyer, D.; Raghunathan, K.; de Rivera, H.; Tegtmeyer, M.; Hawes, D.; Neumann, A.; Nehme, R.; Eggan, K.; McCarroll, S. A.
10.1101/2020.06.29.174383 — genetics — Posted on 2020-06-29
313 Identifying Modules of Cooperating Cancer Drivers
Klein, M. I.; Cannataro, V. L.; Newman, S.; Townsend, J. P.; Stern, D. F.; Zhao, H.
10.1101/2020.06.29.168229 — cancer biology — Posted on 2020-06-29
314 Personalization of mathematical models of human atrial action potential
Pikunov, A. V.; Syunyaev, R. A.; Steckmeister, V.; Kutschka, I.; Voigt, N.; Efimov, I. R.
10.1101/2020.06.29.174870 — biophysics — Posted on 2020-06-29
315 NGS-PrimerPlex: high-throughput primer design for multiplex polymerase chain reactions
Kechin, A.; Borobova, V.; Boyarskikh, U.; Khrapov, E.; Subbotin, S.; Filipenko, M.
10.1101/2020.06.29.176834 — bioinformatics — Posted on 2020-06-29
317 Structure of human RNA Polymerase III
Ramsay, E. P.; Abascal-Palacios, G.; Daiss, J. L.; King, H.; Gouge, J.; Pilsl, M.; Beuron, F.; Morris, E.; Gunkel, P.; Engel, C.; Vannini, A.
10.1101/2020.06.29.177279 — biochemistry — Posted on 2020-06-29
318 Evidence of recent increased pathogenicity within the Australian Ascochyta rabiei population
Thanjavur Sambasivam, P.; Mehmood, Y.; Bar, I.; Davidson, J.; Moore, K.; Hobson, K.; Ford, R.
10.1101/2020.06.28.175653 — plant biology — Posted on 2020-06-29
320 Vertical Stratification in Urban Green Space Aerobiomes
Robinson, J. M.; Dumancela, C. C.; Liddicoat, C.; Weinstein, P.; Cameron, R.; Breed, M.
10.1101/2020.06.28.176743 — ecology — Posted on 2020-06-29
321 Integrating single-cell RNA-seq and imaging with SCOPE-seq2
Liu, Z.; Yuan, J.; Lasorella, A.; Iavarone, A.; Bruce, J. N.; Canoll, P.; Sims, P. A.
10.1101/2020.06.28.176404 — systems biology — Posted on 2020-06-29
322 The Arabidopsis bZIP19 and bZIP23 transcription factors act as zinc-sensors to control plant zinc status
Lilay, G. H.; Persson, D.; Castro, P. H.; Liao, F.; Alexander, R.; Aarts, M. G.; Assuncao, A. G.
10.1101/2020.06.29.177287 — plant biology — Posted on 2020-06-29
327 Weight and organ specific immune cell profiling of Sleeve Gastrectomy
Harris, D. A.; Subramaniam, R.; Brenner, T.; Tavakkoli, A.; Sheu, E. G.
10.1101/2020.06.28.176628 — immunology — Posted on 2020-06-29
332 Size-dependent protein segregation creates a spatial switch for Notch and APP signaling
Kwak, M.; Southard, K. M.; Kim, N. H.; Gopalappa, R.; Kim, W. R.; An, M.; Lee, H. J.; Farlow, J.; Georgakopoulos, A.; Robakis, N. K.; Seo, D.; Kim, H. B.; Kim, Y. H.; Cheon, J.; Gartner, Z. J.; Jun, Y.-w.
10.1101/2020.06.28.176560 — cell biology — Posted on 2020-06-29
334 The long and the short of it: unlocking nanopore long-read RNA sequencing data with short-read tools
Dong, X.; Tian, L.; Gouil, Q.; Kariyawasam, H.; Su, S.; De Paoli-Iseppi, R.; Prawer, Y. D. J.; Clark, M. B.; Breslin, K.; Iminitoff, M.; Blewitt, M. E.; Law, C. W.; Ritchie, M. E.
10.1101/2020.06.28.176727 — bioinformatics — Posted on 2020-06-29
335 Quantitative occupancy of myriad transcription factors from one DNase experiment enables efficient comparisons across conditions
Luo, K.; Zhong, J.; Safi, A.; Hong, L. K.; Tewari, A. K.; Song, L.; Reddy, T. E.; Ma, L.; Crawford, G. E.; Hartemink, A. J.
10.1101/2020.06.28.171587 — bioinformatics — Posted on 2020-06-29
336 Survey of Anisoptera diversity in Flood prone areas in Tirurangadi Taluk of Kerala, India
Kalliyil, A.; Sherin MK, J.; Amal K, A.; Noushad, N.; P, S.; CT, H.; Sahla P, F.; Mathew, B.
10.1101/2020.06.28.168336 — zoology — Posted on 2020-06-29
337 High-resolution mapping of glycoprotein structure-activity relationships by shotgun scanning glycomutagenesis
Li, M.; Zheng, X.; Shanker, S.; Jaroentomeechai, T.; Kocer, I.; Byrne, J.; Cox, E. C.; Labonte, J. W.; Gray, J. J.; DeLisa, M. P.
10.1101/2020.06.28.176198 — synthetic biology — Posted on 2020-06-29
339 SeedExtractor: an open-source GUI for seed image analysis
Zhu, F.; Paul, P.; Hussain, W.; Wallman, K.; Dhatt, B. K.; Sandhu, J.; Irvin, L.; Morota, G.; Yu, H.; Walia, H.
10.1101/2020.06.28.176230 — plant biology — Posted on 2020-06-29
345 High-performance pipeline for MutMap and QTL-seq
Sugihara, Y.; Young, L.; Yaegashi, H.; Natsume, S.; Shea, D. J.; Takagi, H.; Booker, H.; Innan, H.; Terauchi, R.; Abe, A.
10.1101/2020.06.28.176586 — bioinformatics — Posted on 2020-06-29
346 Age-related degeneration leads to gliosis but not regeneration in the zebrafish retina
Martins, R. R.; Zamzam, M.; Moosajee, M.; Thummel, R. B.; Henriques, C. M.; MacDonald, R. B.
10.1101/2020.06.28.174821 — neuroscience — Posted on 2020-06-29
351 Multispecies integrated population model reveals bottom-up dynamics in a seabird predator-prey system
Queroue, M.; Barbraud, C.; Barraquand, F.; Turek, D.; Delord, K.; Pacoureau, N.; Gimenez, O.
10.1101/2020.06.26.174250 — ecology — Posted on 2020-06-29
354 Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation
Cole, S.; Chandra, R.; Harris, M.; Patel, I.; Wang, T.; Kim, H.; Jensen, L.; Russo, S.; Turecki, G.; Gancarz-Kausch, A.; Dietz, D.; Lobo, M. K.
10.1101/2020.06.27.175349 — neuroscience — Posted on 2020-06-29
360 Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure
Becker, J. A.; Pellissier, L. P.; Corde, Y.; Laboute, T.; Leaute, A.; Gandia, J.; Le Merrer, J.
10.1101/2020.06.27.174771 — neuroscience — Posted on 2020-06-29
367 Population GNNs for Brain Age Prediction
Stankeviciute, K.; Azevedo, T.; Campbell, A.; Bethlehem, R. A. I.; Lio, P.
10.1101/2020.06.26.172171 — neuroscience — Posted on 2020-06-29
371 Enhanced specificity of high sensitivity somatic variant profiling in cell-free DNA via paired normal sequencing: design, validation, and clinical experience of the MSK-ACCESS liquid biopsy assay
Brannon, A. R.; Jayakumaran, G.; Diosdado, M.; Patel, J.; Razumova, A.; Hu, Y.; Meng, F.; Haque, M.; Sadowska, J.; Sadowska, J.; Murphy, B.; Baldi, T.; Johnson, I.; Ptashkin, R.; Hasan, M.; Srinivasan, P.; Rema, A. B.; Rijo, I.; Agarunov, A.; Won, H.; Perera, D.; Brown, D. N.; Samolia, A.; Jing, X.; Gedvilaite, E.; Yang, J. L.; Stephens, D. P.; Dix, J.-M.; DeGroat, N.; Nafa, K.; Syed, A.; Li, A.; Lebow, E. S.; Bowman, A. S.; Ferguson, D. C.; Liu, Y.; Mata, D. A.; Sharma, R.; Yang, S.-R.; Bale, T.; Benhamida, J. K.; Chang, J. C.; Dogan, S.; Hameed, M. R.; Hechtman, J. F.; Moung, C.; Ross, D. S.
10.1101/2020.06.27.175471 — genomics — Posted on 2020-06-29
373 Growth impacts in a changing ocean: insights from two coral reef fishes in an extreme environment
D'Agostino, D.; Burt, J. A.; Santinelli, V.; Vaughan, G. O.; Fowler, A.; Reader, T.; Taylor, B. M.; Hoey, A. S.; Cavalcante, G. H.; Bauman, A. G.; Feary, D. A.
10.1101/2020.06.26.174029 — ecology — Posted on 2020-06-29
374 Ontology-guided segmentation and object identification for developmental mouse lung immunofluorescent images
Masci, A. M.; White, S.; Neely, B.; Ardini-Polaske, M.; Hill, C. B.; Misra, R. S.; Aronow, B.; Gaddis, N.; Wert, S. E.; Palmer, S. M.; Chan, C.
10.1101/2020.06.26.174367 — bioinformatics — Posted on 2020-06-29
376 Selective Modulation of Heart and Respiration by Optical Control of Vagus Nerve Axons Innervating the Heart
Fontaine, A. K.; Futia, G. L.; Rajendran, P. S.; Littich, S.; Mizoguchi, N.; Shivkumar, K.; Ardell, J. L.; Restrepo, D.; Caldwell, J. H.; Gibson, E. A.; Weir, R. F.
10.1101/2020.06.26.173898 — bioengineering — Posted on 2020-06-29
377 Highly efficient intercellular spreading of protein misfolding mediated by viral ligand - receptor interactions
Liu, S.; Hossinger, A.; Buravlova, O.; Mueller, S.; Lichtenthaler, S. F.; Neumann, M.; Denner, P.; Vorberg, I. M.
10.1101/2020.06.26.173070 — neuroscience — Posted on 2020-06-29
381 Apple peel and flesh contain pro-neurogenic compounds
Ichwan, M.; Walker, T.; Nicola, Z.; Ludwig-Mueller, J.; Boettcher, C.; Overall, R. W.; Adusumilli, V.; Bulut, M.; Lugo-Hernandez, E. A.; Ramirez-Rodriguez, G.; Kempermann, G.
10.1101/2020.06.25.170266 — neuroscience — Posted on 2020-06-29
382 Analysis and Visualization of Sleep Stages based on Deep Neural Networks
Krauss, P.; Metzner, C.; Joshi, N.; Schulze, H.; Traxdorf, M.; Maier, A.; Schilling, A.
10.1101/2020.06.25.170464 — neuroscience — Posted on 2020-06-29
387 Multi- and transgenerational disruption of maternal behavior and female puberty by Endocrine Disrupting Chemical (EDC) mixture exposure
Lopez Rodriguez, D.; Aylwin, C. F.; Delli, V.; Sevrin, E.; Campanile, M.; Martin, M.; Franssen, D.; Gerard, A.; Blacher, S.; Tirelli, E.; Noel, A.; Lomniczi, A.; Parent, A.-S.
10.1101/2020.06.26.172965 — neuroscience — Posted on 2020-06-29
388 Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine
Gonzalez, J.; Cavelli, M.; Castro-Zaballa, S.; Mondino, A.; Tort, A. B.; Rubido, N.; Carrera, I.; Torterolo, P.
10.1101/2020.06.25.172304 — neuroscience — Posted on 2020-06-29
391 Assessment of the use and quick preparation of saliva for rapid microbiological diagnosis of COVID-19.
Vila, J.; Fernandez-Pittol, M.; Hurtado, J. C.; Moreno-Garcia, E.; Rubio Garcia, E.; Navarro, M.; Valiente, M.; Peiro, A.; Seijas, N.; Capon, A.; Martinez, M. J.; Casals-Pascual, C.
10.1101/2020.06.25.172734 — microbiology — Posted on 2020-06-29
392 A single nucleotide change underlies the genetic assimilation of a plastic trait
Vigne, P.; Gimond, C.; Ferrari, C.; Vielle, A.; Hallin, J.; Pino-Querido, A.; El Mouridi, S.; Frokjaer-Jensen, C.; Boulin, T.; Teotonio, H.; Braendle, C.
10.1101/2020.06.29.176990 — evolutionary biology — Posted on 2020-06-29
395 A critical role for trkB signaling in the adult function of parvalbumin interneurons and prefrontal network dynamics
Guyon, N.; Rakauskas Zacharias, L.; van Lunteren, J. A.; Immenschuh, J.; Fuzik, J.; Märtin, A.; Xuan, Y.; Zilberter, M.; Kim, H.; Meletis, K.; Lopes-Aguiar, C.; Carlen, M.
10.1101/2020.06.28.175927 — neuroscience — Posted on 2020-06-29
396 Generation of a DAT-Flp mouse line for intersectional genetic targeting of dopamine neuron subpopulations
Kramer, D. J.; Kosillo, P.; Friedmann, D.; Stafford, D.; Luo, L.; Lee, A. Y.-F.; Hockemeyer, D.; Ngai, J.; Bateup, H. S.
10.1101/2020.06.24.167908 — neuroscience — Posted on 2020-06-29
403 Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology
Nair, R. R.; Zabezhinsky, D.; Gelin-Licht, R.; Haas, B. J.; Dyhr, M. C. A.; Sperber, H. S.; Nusbaum, C.; Gerst, J. E.
10.1101/2020.06.28.175851 — cell biology — Posted on 2020-06-28
405 A neural circuit for flexible control of persistent behavioral states
Ji, N.; Madan, G. K.; Fabre, G. I.; Dayan, A.; Baker, C. M.; Nwabudike, I.; Flavell, S. W.
10.1101/2020.02.04.934547 — neuroscience — Posted on 2020-06-28
407 Atlas and developmental dynamics of mouse DNase I hypersensitive sites
Breeze, C. E.; Lazar, J.; Mercer, T.; Halow, J.; Washington, I.; Lee, K.; Ibarrientos, S.; Castillo, A.; Neri, F.; Haugen, E.; Rynes, E.; Reynolds, A.; Bates, D.; Diegel, M.; Dunn, D.; Kaul, R.; Sandstrom, R.; Meuleman, W.; Bender, M. A.; Groudine, M.; Stamatoyannopoulos, J. A.
10.1101/2020.06.26.172718 — genomics — Posted on 2020-06-28
410 Genetics of human gut microbiome composition
Kurilshikov, A.; Medina-Gomez, C.; Bacigalupe, R.; Radjabzadeh, D.; Wang, J.; Demirkan, A.; Le Roy, C. I.; Raygoza Garay, J. A.; Finnicum, C.; Liu, X.; Zhernakova, D.; Bonder, M. J.; Hansen, T. H.; Frost, F.; Ruhlemann, M. C.; Turpin, W.; Moon, J.-Y.; Kim, H.-N.; Lull, K.; Barkan, E.; Shah, S. A.; Fornage, M.; Szopinska-Tokov, J.; Wallen, Z.; Borisevich, D.; Agreus, L.; Andreasson, A.; Bang, C.; Bedrani, L.; Bell, J. T.; Bisgaard, H.; Boehnke, M.; Boomsma, D. I.; Burk, R. D.; Claringbould, A.; Croitoru, K.; Davies, G.; Van Duijn, C.; Duijts, L.; Falony, G.; Fu, J.; van der Graaf, A.; Hansen, T
10.1101/2020.06.26.173724 — genetics — Posted on 2020-06-28
412 A stochastic hybrid model for DNA replication incorporating protein mobility dynamics
Windhager, J.; Paine, A.; Nathanailidou, P.; Tasiudi, E.; Rodriguez Martinez, M.; Lygerou, Z.; Lygeros, J.; Rapsomaniki, M. A.
10.1101/583187 — systems biology — Posted on 2020-06-28
415 Mesoscopic cortical network reorganization during recovery of partial optic nerve injury in GCaMP6s mice
Groleau, M.; Nazari-Ahangarkolaee, M.; Vanni, M. P.; Higgins, J. L.; Vezina Bedard, A.-S.; Sabel, B.; Mohajerani, M. H.; Vaucher, E.
10.1101/2020.06.28.173799 — neuroscience — Posted on 2020-06-28
417 Unexpected opposing biological effect of genetic risk factors for Parkinson disease
Keatinge, M.; Gegg, M.; Watson, L.; Mortiboys, H.; Li, N.; Dunning, M. J.; Ailani, D.; Bui, H.; van Leens, A.; Lefeber, D.; MacDonald, R.; Schapira, A.; Bandmann, O.
10.1101/702340 — neuroscience — Posted on 2020-06-28
419 Modification of streptococcal cell wall polysaccharide spatially controls cell division
Zamakhaeva, S.; Chaton, C. T.; Rush, J. S.; Ajay Castro, S.; Yarawsky, A. E.; Herr, A. B.; van Sorge, N. M.; Dorfmueller, H. C.; Frolenkov, G. I.; Korotkov, K. V.; Korotkova, N.
10.1101/2020.06.26.173716 — microbiology — Posted on 2020-06-28
420 Identification of cellular context sensitive regulatory variation in mouse genomes
Maurano, M. T.; Halow, J.; Byron, R.; Groudine, M.; Bender, M. A.; Stamatoyannopoulos, J. A.
10.1101/2020.06.27.175422 — genomics — Posted on 2020-06-28
422 Two-Photon Microperimetry: A media opacity-independent retinal function assay
Wei, A.; Mehta, U. V.; Palczewska, G.; Palma, A. M.; Hussey, V. M.; Hoffmann, L. E.; Diep, A.; Nguyen, K.; Le, B.; Chang, S. Y.-S.; Browne, A. W.
10.1101/2020.06.27.175315 — bioengineering — Posted on 2020-06-28
424 Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2
Kim, Y.; Wower, J.; Maltseva, N.; Chang, C.; Jedrzejczak, R.; Wilamowski, M.; Kang, S.; Nicolaescu, V.; Randall, G.; Michalska, K.; Joachimiak, A.
10.1101/2020.06.26.173872 — molecular biology — Posted on 2020-06-28
426 LINE-1 expression in cancer correlates with DNA damage response, copy number variation, and cell cycle progression
McKerrow, W.; Wang, X.; Mita, P.; Cao, S.; Grivainis, M.; Ding, L.; LaCava, J.; Boeke, J.; Fenyö, D.
10.1101/2020.06.26.174052 — cancer biology — Posted on 2020-06-28
427 Bayesian Evaluation of Temporal Signal in Measurably Evolving Populations
Duchene, S.; Lemey, p.; Stadler, T.; Ho, S. Y.; Duchene, D. A.; Dhanasekaran, V.; Baele, G.
10.1101/810697 — bioinformatics — Posted on 2020-06-28
429 Endo-lysosomal Aβ concentration and pH enable formation of Aβ oligomers that potently induce Tau missorting
Schützmann, M. P.; Hasecke, F.; Bachmann, S.; Zielinski, M.; Hänsch, S.; Schröder, G. F.; Zempel, H.; Hoyer, W.
10.1101/2020.06.28.175885 — biochemistry — Posted on 2020-06-28
431 The SAGE genetic toolkit enables highly efficient, iterative site-specific genome engineering in bacteria
Elmore, J. R.; Dexter, G. N.; Francis, R.; Riley, L.; Huenemann, J.; Baldino, H.; Guss, A. M.; Egbert, R.
10.1101/2020.06.28.176339 — synthetic biology — Posted on 2020-06-28
432 Alpha-synuclein supports interferon stimulated gene expression in neurons
Massey, A. R.; Monogue, B.; Chen, Y.; Lesteberg, K.; Johnson, M. E.; Bergkvist, L.; Steiner, J.; Ma, J.; Mahalingam, R.; Kleinschmidt-Demasters, B. K.; Escobar Galvis, M.; Brundin, P.; Kunath, T.; Beckham, J. D.
10.1101/2020.04.25.061762 — neuroscience — Posted on 2020-06-28
433 Automatic subtyping of individuals with Primary Progressive Aphasia
Themistocleous, C.; Ficek, B.; Webster, K.; den Ouden, D.-B.; Hillis, A. E.; Tsapkini, K.
10.1101/2020.04.04.025593 — neuroscience — Posted on 2020-06-28
435 Bi-compartmentalized stem cell organization of the corneal limbal niche
Farrelly, O.; Suzuki-Horiuchi, Y.; Brewster, M.; Kuri, P.; Huang, S.; Rice, G.; Xu, J.; Dentchev, T.; Lee, V.; Rompolas, P.
10.1101/2020.06.25.171462 — developmental biology — Posted on 2020-06-28
438 An Effector Index to Predict Causal Genes at GWAS Loci
Forgetta, V.; Jiang, L.; Vulpescu, N. A.; Hogan, M. S.; Chen, S.; Morris, J. A.; Grinek, S.; Benner, C.; Mccarthy, M. I.; Fauman, E.; Greenwood, C. M.; Maurano, M. T.; Richards, J. B.
10.1101/2020.06.28.171561 — bioinformatics — Posted on 2020-06-28
439 Malaria in Pregnancy Regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 Efflux Transporters in the Mouse Visceral Yolk Sac
Martinelli, L. M.; Fontes, K. N.; Reginatto, M. W.; Andrade, C. B.; Monteiro, V. R.; Gomes, H. R.; Silva-Filho, J. L.; Pinheiro, A. A.; Vago, A. R.; Almeida, F. R.; Bloise, F. F.; Matthews, S. G.; Ortiga-Carvalho, T. M.; Bloise, E.
10.1101/2020.06.27.175018 — pharmacology and toxicology — Posted on 2020-06-28
442 Quantitative trait locus mapping identifies Col4a6 as a novel regulator of striatal dopamine level and axonal branching in mice.
Buttini, M.; Thomas, M. H.; Gui, Y.; Garcia, P.; Karout, M.; Jaeger, C.; Hodak, Z.; Michelucci, A.; Kollmus, H.; Centeno, A.; Schughart, K.; Balling, R.; Mittelbronn, M.; Nadeau, J.; Williams, R. W.; Sauter, T.; Sinkkonen, L.
10.1101/2020.06.28.176206 — neuroscience — Posted on 2020-06-28
445 Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk
Pined, S.; Nikolova-Krstevski, V.; Leimena, C.; Atkinson, A. J.; Altekoester, A.-K.; Cox, C. D.; Jacoby, A.; Huttner, I. G.; Ju, Y.-K.; Soka, M.; Ohanian, M.; Trived, G.; Johnson, R.; Molenaar, P.; Kuchar, D.; Allen, D. G.; Hill, A. P.; Bodmer, R.; Vogler, G.; Dobrzyn, H.; Ocorr, K.; Fatkin, D.
10.1101/2020.06.28.176495 — genetics — Posted on 2020-06-28
446 The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome
Ferro, I.; Gavini, J.; Bracher, L.; Landolfo, M.; Candinas, D.; Stroka, D.; Polacek, N.
10.1101/2020.06.28.175810 — cell biology — Posted on 2020-06-28
447 Intense expression of Neurokinin-1 Receptor is associated with Urothelial carcinoma
mehboob, r.; Hassan, a.; Perveen, S.; Gilani, S. A.; Waseem, H.; Ahmad, f. J.; Akram, J.
10.1101/2020.06.27.175026 — pathology — Posted on 2020-06-28
448 Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme
Fedoryshchak, R. O.; Prechova, M.; Butler, A.; Lee, R.; O'Reilly, N.; Flynn, H.; Snijders, A. P.; Eder, N.; Ultanir, S.; Mouilleron, S.; Treisman, R.
10.1101/2020.06.28.176040 — molecular biology — Posted on 2020-06-28
449 Dietary emulsifiers alter composition and activity of the human gut microbiota in vitro, irrespective of chemical or natural emulsifier origin.
Miclotte, L. M. G.; De Paepe, K.; Callewaert, C.; Raes, J.; Rymenans, L.; Rajkovic, A.; Van Camp, J.; Van de Wiele, T.
10.1101/2020.06.28.174946 — microbiology — Posted on 2020-06-28
451 The Atlas of the In Vivo HIV CD4 T Cell Reservoir
Neidleman, J.; Luo, X.; Frouard, J.; Xie, G.; Hsiao, F.; Ma, T.; Morcilla, V.; Lee, A.; Telwatte, S.; Thomas, R.; Tamaki, W.; Wheeler, B.; Hoh, R.; Vohra, P.; Milush, J.; James, K. S.; Archin, N.; Hunt, P. W.; Deeks, S. G.; Yukl, S. A.; Palmer, S.; Greene, W. C.; Roan, N. R.
10.1101/2020.06.27.175745 — immunology — Posted on 2020-06-28
456 Characterizing the molecular regulation of inhibitory immune checkpoints with multi-modal single-cell screens
Papalexi, E.; Mimitou, E.; Butler, A. W.; Foster, S.; Bracken, B.; Mauck, W. M.; Wessels, H.-H.; Yeung, B. Z.; Smibert, P.; Satija, R.
10.1101/2020.06.28.175596 — genomics — Posted on 2020-06-28
457 A conserved role for sleep in supporting spatial learning in Drosophila
Melnattur, K.; Kirszenblat, L.; Morgan, E.; Militchin, V.; Sakran, B.; English, D.; Patel, R.; Chan, D.; van Swinderen, B.; Shaw, P. J.
10.1101/2020.06.27.174656 — neuroscience — Posted on 2020-06-28
458 Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster
Olivares, G. H.; Nunez, F.; Candia, N.; Orostica, K.; Vega-Macaya, F.; Zuniga, N.; Molina, C.; Mackay, T. F. C.; Verdugo, R.; Olguin, P.
10.1101/2020.06.28.175356 — genetics — Posted on 2020-06-28
459 Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes
Sheard, T.; Colyer, J.; Jayasinghe, I.; Valdivia, H.; Howlett, L.; Kirton, H.; Yang, Z.; Steele, D.; Gurrola, G.
10.1101/2020.06.26.131854 — cell biology — Posted on 2020-06-28
460 Application of Airy beam Light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids
Adhya, D.; Chennell, G.; Crowe, J.; Valencia-Alarcon, E.; Seyforth, J.; Hosny, N.; Yasvoina, M. V.; Forster, R.; Baron-Cohen, S.; Vernon, A. C.; Srivastava, D. P.
10.1101/2020.06.27.174904 — neuroscience — Posted on 2020-06-28
462 The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases
Coleman, J. L. J.; Ngo, T.; Smythe, R. E.; Cleave, A. J.; Jones, N. M.; Graham, R. M.; Smith, N. J.
10.1101/2020.06.27.174847 — biochemistry — Posted on 2020-06-28
463 The mitochondrial genomes of 11 aquatic macroinvertebrate species from Cyprus
Macher, J.-N.; Drakou, K.; Papatheodoulou, A.; van der Hoorn, B.; Vasquez, M.
10.1101/2020.06.26.173625 — molecular biology — Posted on 2020-06-28
464 Classification of grain amaranths using chromosome-level genome assembly of ramdana, A. hypochondriacus
Deb, S.; Jayaprasad, S.; Ravi, S.; K, R. R.; Whadgar, S.; Dixit, S.; Sunil, M.; Choudhary, B.; Stevanato, P.; Ramireddy, E.; Srinivasan, S.
10.1101/2020.06.27.174920 — genomics — Posted on 2020-06-28
465 Intestinal progenitor P-bodies maintain stem cell identity by suppressing pro-differentiation factors.
Buddika, K.; Huang, Y.-T.; Butrum-Griffith, A.; Norrell, S. A.; OConnor, A. M.; Patel, V. K.; Rector, S. A.; Slovan, M.; Sokolowski, M.; Kato, Y.; Nakamura, A.; Sokol, N. S.
10.1101/2020.06.27.175398 — cell biology — Posted on 2020-06-28
466 Activation of the Crtc2/Creb1 transcriptional network in skeletal muscle enhances weight loss during intermittent fasting
Bruno, N.; Nwachukwu, J. C.; Srinivasan, S.; Sturgill, D.; Hager, G.; Hurst, S.; Sheu, S.-S.; Conkright, M.; Nettles, K. W.
10.1101/2020.06.27.175323 — physiology — Posted on 2020-06-28
467 3-Dimensional Magnetic Resonance Imaging of the Freely Moving Human Eye
Franceschiello, B.; Di Sopra, L.; Minier, A.; Ionta, S.; Zeugin, D.; Notter, M. P.; Bastiaansen, J. A. M.; Jorge, J.; Yerly, J.; Stuber, M.; Murray, M. M.
10.1101/2020.06.26.172791 — bioengineering — Posted on 2020-06-28
469 Thyroid Hormones-Thyrotropin Interrelationships in Thyroid Dysfunction States
Lamichhane, T. R.; Pant, S. P.; Lamichhane, B.; Paudel, S.; Yadav, B. K.; Lamichhane, H. P.
10.1101/2020.06.26.173252 — biochemistry — Posted on 2020-06-28
470 First responders shape a prompt and sharp NF-Bκ-mediated transcriptional response to TNF-α
Zambrano, S.; Loffreda, A.; Carelli, E.; Stefanelli, G.; Colombo, F.; Bertrand, E.; Tacchetti, C.; Agresti, A.; Bianchi, M. E.; Molina, N.; Mazza, D.
10.1101/2020.06.27.174995 — systems biology — Posted on 2020-06-28
475 Title: Two-Photon Microperimetry: A media opacity-independent retinal function assay
Wei, A.; Mehta, U. V.; Palczewska, G.; Palma, A. M.; Hussey, V. M.; Hoffmann, L. E.; Diep, A.; Nguyen, K.; Le, B.; Chang, S. Y.-S.; Browne, A. W.
10.1101/2020.06.27.175315 — bioengineering — Posted on 2020-06-28
476 Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms
Julienne, H.; Laville, V.; McCaw, Z. R.; He, Z.; Guillemot, V.; Lasry, C.; Ziyatdinov, A.; Vaysse, A.; Lechat, P.; Menager, H.; Le Goff, W.; Dube, M.-P.; Kraft, P.; Ionita-Laza, I.; Vilhjalmsson, B. J.; Aschard, H.
10.1101/2020.06.26.172999 — genetics — Posted on 2020-06-28
477 Variation in transparency degree: response to light availability or part of mimicry syndrome?
Arias, M.; Barbut, J.; Rougerie, R.; Dutry, M.; Kohler, M.; Laulan, B.; Paillard, C.; Berthier, S.; Andraud, C.; Elias, M.; Gomez, D.
10.1101/2020.06.26.172932 — evolutionary biology — Posted on 2020-06-28
482 BBB pathophysiology independent delivery of siRNA in traumatic brain injury
Li, W.; Qiu, J.; Li, X.-L.; Aday, S.; Zhang, J.; Conley, G.; Xu, J.; Langer, R.; Mannix, R.; Karp, J. M.; Joshi, N.
10.1101/2020.06.26.173393 — bioengineering — Posted on 2020-06-28
486 Population genomic and historical analysis reveals a global invasion by bridgehead processes in Mimulus guttatus
Vallejo-Marin, M.; Friedman, J.; Twyford, A. D.; Lepais, O.; Ickert-Bond, S. M.; Streisfeld, M. A.; Yant, L.; van Kleunen, M.; Rotter, M. C.; Puzey, J. R.
10.1101/2020.06.26.173286 — evolutionary biology — Posted on 2020-06-28
487 Fast 3D imaging of giant unilamellar vesicles using reflected light-sheet microscopy with single molecule sensitivity
Szilagyi, S. A.; Burmeister, M.; Davis, Q. T.; Hermsdorf, G. L.; De, S.; Schäffer, E.; Jannasch, A.
10.1101/2020.06.26.174102 — biophysics — Posted on 2020-06-28
491 Prognostic significance of Substance P/ Neurokinin 1 receptor and its association with hormonal receptors in breast carcinoma
mehboob, r.; Gilani, S. A.; Hassan, a.; Tanvir, I.; Khan, R.; Babar, M. E.; Akram, J.; Ahmad, F.; Munoz, M.; Shahi, s.
10.1101/2020.06.27.175083 — pathology — Posted on 2020-06-28
492 Quantifying Color Vision Changes Associated with Cataracts Using Cone Contrast Thresholds
Mehta, U.; Diep, A.; Nguyen, K.; Le, B.; Yuh, C.; Frambach, C.; Doan, J.; Wei, A.; Palma, A. M.; Farid, M.; Garg, S.; Kedhar, S.; Wade, M.; Marshall, K. A.; Jameson, K. A.; Kenney, M. C.; Browne, A. W.
10.1101/2020.06.27.175570 — pathology — Posted on 2020-06-28
493 A Role for Maternal Factors in Suppressing Cytoplasmic Incompatibility
Momtaz, A. Z.; Ahumada Sabagh, A. D.; Gonzalez Amortegui, J.; Salazar, S. A.; Hernandez, J.; Finessi, A.; Christensen, S.; Serbus, L. R.
10.1101/2020.06.27.174805 — microbiology — Posted on 2020-06-28
497 A collection of programs for one-dimensional Ising analysis of linear repeat proteins with point substitutions
Marold, J.; Sforza, K.; Geiger-Schuller, K.; Aksel, T.; Klein, S.; Petersen, M.; Poliakova-Georgantas, E.; Barrick, D.
10.1101/2020.06.27.175224 — biophysics — Posted on 2020-06-28
498 BERTology Meets Biology: Interpreting Attention in Protein Language Models
Vig, J.; Madani, A.; Varshney, L. R.; Xiong, C.; Socher, R.; Rajani, N. F.
10.1101/2020.06.26.174417 — bioinformatics — Posted on 2020-06-28
500 Accessible, Reproducible, and Scalable Machine Learning for Biomedicine
Gu, Q.; Kumar, A.; Bray, S. A.; Creason, A.; Khanteymoori, A.; Jalili, V.; Gruning, B.; Goecks, J.
10.1101/2020.06.25.172445 — bioinformatics — Posted on 2020-06-28
502 Gazing into the Metaboverse: Automated exploration and contextualization of metabolic data
Berg, J. A.; Zhou, Y.; Waller, T. C.; Ouyang, Y.; Nowinski, S. M.; Van Ry, T.; George, I.; Cox, J. E.; Wang, B.; Rutter, J.
10.1101/2020.06.25.171850 — biochemistry — Posted on 2020-06-28
503 Genetic Variability affects the Skeletal Response to Unloading
Friedman, M. A.; Abood, A.; Senwar, B.; Zhang, Y.; Maroni, C. R.; Ferguson, V. L.; Farber, C. R.; Donahue, H. J.
10.1101/2020.06.26.174326 — genetics — Posted on 2020-06-28
505 Regional expression profiles of risk genes for depression are associated with brain activation patterns in emotion and reward tasks
Komorowski, A.; Vidal, R.; Singh, A.; Murgas, M.; Pena-Centeno, T.; Gryglewski, G.; Kasper, S.; Wiltfang, J.; Lanzenberger, R.; Goya-Maldonado, R.
10.1101/2020.06.27.175257 — neuroscience — Posted on 2020-06-27
506 Estimation of the number of synapses in the hippocampus and brain-wide by volume electron microscopy and genetic labeling
Santuy, A.; Tomas-Roca, L.; Rodriguez, J.-R.; Gonzalez-Soriano, J.; Zhu, F.; Qiu, Z.; Grant, S. G.; DeFelipe, J.; Merchan-Perez, A.
10.1101/2020.02.18.953802 — neuroscience — Posted on 2020-06-27
510 VGLUT3-p.A211V variant fuses stereocilia bundle and elongates synaptic ribbons in the human deafness DFNA25
Joshi, Y.; Miot, S.; Guillet, M.; Sendin, G.; Bourien, J.; Wang, J.; Pujol, R.; El Mestikawy, S.; Puel, J.-L.; Nouvian, R.
10.1101/2020.06.26.170852 — neuroscience — Posted on 2020-06-27
513 MAP Kinase OsMEK2 and OsMPK1 Signaling for Ferroptotic Cell Death in Rice-Magnaporthe oryzae Interactions
Jwa, N.-S.; Dangol, S.; Singh, R.; Nguyen, N. K.; Chen, Y.; Wang, J.; Lee, H. G.; Hwang, B. K.
10.1101/2020.06.26.174292 — molecular biology — Posted on 2020-06-27
515 Impact of a rapid decline in malaria transmission on antimalarial IgG subclasses and avidity
Ssewanyana, I.; Rek, J.; Rodriguez, I.; Wu, L.; Arinaitwe, E.; Nankabirwa, J.; Beeson, J.; Mayanja- Kizza, H.; Rosenthal, P.; Dorsey, G.; Kamya, M.; Drakeley, C.; Greenhouse, B.; Tetteh, K. K.
10.1101/2020.06.26.173005 — immunology — Posted on 2020-06-27
516 Novel mode of filament formation in UPA-promoted CARD8 and NLRP1 Inflammasomes
Hollingsworth, L. R.; David, L.; Li, Y.; Griswold, A. R.; Sharif, H.; Fontana, P.; Fu, T.-M.; Ruan, J.; Bachovchin, D. A.; Wu, H.
10.1101/2020.06.27.175497 — immunology — Posted on 2020-06-27
517 NK cells acquire PD-1 from the membrane of tumor cells.
Hasim, M. S.; Vulpis, E.; Sciume, G.; Shih, H.-Y.; Scheer, A.; MacMillan, O.; Petrucci, M. T.; Santoni, A.; Zingoni, A.; Ardolino, M.
10.1101/2020.06.26.174342 — immunology — Posted on 2020-06-27
518 Circulating bile acid levels direct sex-differences in liver cancer development
Patton, M. E.; Kelekar, S.; Taylor, L. J.; Thakare, R.; Lee, S.; Alnouti, Y.; Madak-Erdogan, Z.; Lee, J.-S.; Finegold, M. J.; Anakk, S.
10.1101/2020.06.25.172635 — cancer biology — Posted on 2020-06-27
519 LINE-1 expression in cancer correlates with DNA damage response, copy number variation, and cell cycle progression
McKerrow, W. H.; Wang, X.; Mita, P.; Cao, S.; Grivainis, M.; Ding, L.; LaCava, J.; Boeke, J.; Fenyö, D. H.
10.1101/2020.06.26.174052 — cancer biology — Posted on 2020-06-27
523 Evaluating aerosol and splatter following dental procedures: addressing new challenges for oral healthcare and rehabilitation
Allison, J.; Currie, C.; Edwards, D.; Bowes, C.; Coulter, J.; Pickering, K.; Kozhevnikova, E.; Durham, J.; Nile, C.; Jakubovics, N.; Rostami, N.; Holliday, R.
10.1101/2020.06.25.154401 — microbiology — Posted on 2020-06-27
526 Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood
Marquardt, N.; Scharenberg, M.; Mold, J. E.; Hard, J.; Kekalainen, E.; Buggert, M.; Nguyen, S.; Wilson, J. N.; Al-Ameri, M.; Ljunggren, H.-G.; Michaelsson, J.
10.1101/2019.12.20.883785 — immunology — Posted on 2020-06-27
527 Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Tian, R.; Abarientos, A.; Hong, J.; Hashemi, S. H.; Yan, R.; Nalls, M. A.; Singleton, A. B.; Faghri, F.; Xu, K.; Kampmann, M.
10.1101/2020.06.27.175679 — genomics — Posted on 2020-06-27
528 Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1
Brownstein, Z.; Gulsuner, S.; Walsh, T.; Martins, F. T. A.; Taiber, S.; Isakov, O.; Lee, M.; Bordeynik-Cohen, M.; Birkan, M.; Chang, W.; Casadei, S.; Danial-Farran, N.; Abu Rayyan, A.; Carlson, R.; Kamal, L.; Arnporsson, A. O.; Sokolov, M.; Gilony, D.; Lipschitz, N.; Frydman, M.; Davidov, B.; Macarov, M.; Sagi, M.; Vinkler, C.; Poran, H.; Sharony, R.; Samara, N.; Zvi, N.; Baris-Feldman, H.; Singer, A.; Handzel, O.; Hertzano, R.; Ali-Naffaa, D.; Ruhrman-Shahar, N.; Madgar, O.; Sofrin, E.; Peleg, A.; Khayat, M.; Shohat, M.; Basel-Salmon, L.; Pras, E.; Lev, D.; Wolf, M.; Steingrimsson, E.; Shomro
10.1101/2020.06.11.144790 — genetics — Posted on 2020-06-27
531 Cryo-EM Structures of Respiratory bc1-cbb3 type CIII2CIV Super-complex and Electronic Communication Between the Complexes
Steimle, S.; VanEeuwen, T.; Ozturk, Y.; Kim, H. J.; Braitbard, M.; Selamoglu, N.; Garcia, B. A.; Schneidman-Duhovny, D.; Murakami, K.; Daldal, F.
10.1101/2020.06.27.175620 — biochemistry — Posted on 2020-06-27
532 Dissociation between catecholamines and acetylcholine in the human cerebral cortex
Pfeffer, T.; Ponce-Alvarez, A.; Meindertsma, T.; Gahnstrom, C.; van den Brink, R. L.; Nolte, G.; Tsetsos, K.; Engel, A. K.; Deco, G.; Donner, T. H.
10.1101/2020.06.25.171199 — neuroscience — Posted on 2020-06-27
536 Pan-transcriptome-based Candidate Therapeutic Discovery for Idiopathic Pulmonary Fibrosis
Wang, Y.; Yella, J. K.; Ghandikota, S.; Cherukuri, T. C.; Ediga, H. H.; Madala, S. K.; Jegga, A. G.
10.1101/824367 — genomics — Posted on 2020-06-27
538 Uncovering new drug properties in target-based drug-drug similarity networks
Udrescu, L.; Bogdan, P.; Chis, A.; Sirbu, I. O.; Topirceanu, A.; Varut, R.-M.; Udrescu, M.
10.1101/2020.03.12.988600 — bioinformatics — Posted on 2020-06-27
539 Superabsorbent crosslinked bacterial cellulose biomaterials for chronic wound dressings
Ciecholewska-Jusko, D.; Zywicka, A.; Junka, A.; Drozd, R.; Sobolewski, P.; Migdal, P.; Kowalska, U.; Toporkiewicz, M.; Fijalkowski, K.
10.1101/2020.03.04.975003 — bioengineering — Posted on 2020-06-27
543 Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions
Liu, W.; Taso, O.; Wang, R.; Bayram, S.; Garcia-Reitboeck, P.; Mallach, A.; Andrews, W. D.; Piers, T. M.; Graham, A. C.; Botia, J. A.; Pocock, J. M.; Cummings, D. M.; Hardy, J.; Edwards, F. A.; Salih, D. A.
10.1101/449884 — neuroscience — Posted on 2020-06-27
547 Cytoplasmic incompatibility between Old and New World populations of a tramp ant
Ün, C.; Schultner, E.; Manzano-Marin, A.; Florez, L. V.; Seifert, B.; Heinze, J.; Oettler, J.
10.1101/2020.03.13.988675 — evolutionary biology — Posted on 2020-06-27
549 Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification
Mouilleau, V.; Vaslin, C.; Gribaudo, S.; Robert, R.; Nicolas, N.; Jarrige, M.; Terray, A.; Lesueur, L.; Mathis, M. W.; Croft, G.; Daynac, M.; ROUILLER-FABRE, V.; Wichterle, H.; Ribes, V.; Martinat, C.; Nedelec, S.
10.1101/2020.06.27.175646 — developmental biology — Posted on 2020-06-27
550 Carbon ion dosimetry on a fluorescent nuclear track detector using widefield microscopy
Walsh, D. W. M.; Liew, H.; Schlegel, J.; Mairani, A.; Abdollahi, A.; Niklas, M.
10.1101/2020.03.13.990325 — biophysics — Posted on 2020-06-27
551 An α-cyanostilbene derivative for the enhanced detection and imaging of amyloid fibril aggregates
Marzano, N. R.; Wray, K. M.; Johnston, C. L.; Paudel, B. P.; Hong, Y.; van Oijen, A. M.; Ecroyd, H.
10.1101/2020.06.25.172627 — biochemistry — Posted on 2020-06-27
553 Isoform transcriptome of developing human brain provides new insights into autism risk variants
Chau, K.; Zhang, P.; Urresti, J.; Amar, M.; Pramod, A. B.; Thomas, A.; Corominas, R.; Lin, G. N.; Iakoucheva, L. M.
10.1101/2020.06.27.175489 — neuroscience — Posted on 2020-06-27
556 Altered Affective Behaviors in Casein Kinase 1 Epsilon Mutant Mice
Zhou, L.; Fitzpatrick, K.; Olker, C.; Vitaterna, M. H.; Turek, F. W.
10.1101/2020.06.26.158600 — neuroscience — Posted on 2020-06-27
558 Evidence of Chitin in the Ampullae of Lorenzini of Chondrichthyan Fishes
Phillips, M.; Tang, W. J.; Robinson, M.; Ocampo Daza, D.; Hassan, K.; Leppert, V.; Hirst, L. S.; Amemiya, C. T.
10.1101/687301 — molecular biology — Posted on 2020-06-27
560 Novel insights into the taxonomic diversity and molecular mechanisms of bacterial Mn(III) reduction
Szeinbaum, N.; Nunn, B. L.; Cavazos, A. R.; Crowe, S. A.; Stewart, F. J.; DiChristina, T. J.; Reinhard, C. T.; Glass, J. B.
10.1101/695007 — microbiology — Posted on 2020-06-27
562 Atlas and developmental dynamics of mouse DNase I hypersensitive sites
Breeze, C. E.; Lazar, J.; Mercer, T.; Halow, J.; Washington, I.; Lee, K.; Ibarrientos, S.; Castillo, A.; Neri, F.; Haugen, E.; Rynes, E.; Reynolds, A.; Bates, D.; Diegel, M.; Dunn, D.; Kaul, R.; Sandstrom, R.; Meuleman, W.; Bender, M. A.; Groudine, M.; Stamatoyannopoulos, J. A.
10.1101/2020.06.26.172718 — genomics — Posted on 2020-06-27
563 Converging evidence for shared genetic underpinnings of genetic generalized epilepsy and background EEG oscillations
Stevelink, R.; Luykx, J. J.; Lin, B.; Leu, C.; Lal, D.; Smith, A.; Schijven, D.; Carpay, J.; Rademaker, K.; Baldez, R.; Braun, K.; Jansen, F.; Epi25 Collaborative, ; ILAE Consortium, ; Smit, D.; Koeleman, B.
10.1101/711200 — genetics — Posted on 2020-06-27
565 A multi-omic integrative scheme characterizes tissues of action at loci associated with type 2 diabetes
Torres, J. M.; Abdalla, M.; Payne, A.; Fernandez-Tajes, J.; Thurner, M.; Nylander, V.; Gloyn, A. L.; Mahajan, A.; Mccarthy, M. M.
10.1101/2020.06.25.169706 — genetics — Posted on 2020-06-27
566 Deep ancestral introgression shapes evolutionary history of dragonflies and damselflies
Suvorov, A.; Scornavacca, C.; Fujimoto, M. S.; Bodily, P.; Clement, M.; Crandall, K. A.; Whiting, M. F.; Schrider, D. R.; Bybee, S. M.
10.1101/2020.06.25.172619 — evolutionary biology — Posted on 2020-06-27
568 Sapphire-Supported Nanopores for Low-Noise DNA Sensing
Xia, P.; Zuo, J.; Paudel, P.; Choi, S.; Chen, X.; Song, W.; Im, J.; Wang, C.
10.1101/2020.03.02.973826 — bioengineering — Posted on 2020-06-27
569 Coupling Day Length Data and Genomic Prediction tools for Predicting Time-Related Traits under Complex Scenarios
Jarquin, D.; Kajiya-Kanegae, H.; Taishen, C.; Yabe, S.; Persa, R.; Yu, J.; Nakagawa, H.; Yamasaki, M.; Iwata, H.
10.1101/703488 — genomics — Posted on 2020-06-27
570 Evolution of the DAN gene family in vertebrates
Opazo, J. C.; Hoffmann, F. G.; Zavala, K.; Edwards, S. V.
10.1101/794404 — evolutionary biology — Posted on 2020-06-27
572 POMC-specific knockdown of Tril reduces body adiposity and increases hypothalamic leptin responsiveness
Moura-Assis, A.; de Lima-Junior, J. C.; Nogueira, P. A.; Simabuco, F. M.; Gaspar, J. M.; Junior, J. D.; Velloso, L. A.
10.1101/2020.06.25.172379 — neuroscience — Posted on 2020-06-27
573 Metabolism modulates global synchrony in the aging brain
Weistuch, C.; Mujica-Parodi, L. R.; Amgalan, A.; Dill, K. A.
10.1101/2020.04.17.047233 — neuroscience — Posted on 2020-06-27
577 Calculating metalation in cells reveals CobW acquires CoII for vitamin B12 biosynthesis upon binding nucleotide
Young, T. R.; Martini, M. A.; Osman, D.; Morton, R. J.; Deery, E.; Warren, M. J.; Robinson, N. J.
10.1101/2020.06.26.173062 — biochemistry — Posted on 2020-06-27
578 Monoterpenes alter TAR1-driven physiology in Drosophila species
Finetti, L.; Tiedemann, L.; Zhang, X.; Civolani, S.; Bernacchia, G.; Roeder, T.
10.1101/2020.06.26.173732 — animal behavior and cognition — Posted on 2020-06-27
582 The genetic architecture of fruit colour in strawberry (Fragaria x ananassa) uncovers the predominant contribution of the F. vesca subgenome to anthocyanins and reveals underlying genetic variations
Labadie, M.; Vallin, G.; Petit, A.; Ring, L.; Hoffmann, T.; Gaston, A.; Potier, A.; Munoz Blanco, J.; Caballero Repullo, J. L.; Schwab, W.; Rothan, C.; Denoyes, B.
10.1101/2020.06.25.171496 — genetics — Posted on 2020-06-27
585 Expression of HPV oncogenes from a single integration site in cervical cancer cell lines
Yu, L.; Lobanov, A.; Majerciak, V.; Mirza, S.; Band, V.; Liu, H.; Cam, M.; Zheng, Z.-M.
10.1101/2020.06.25.171959 — cancer biology — Posted on 2020-06-27
588 Structures, conformations and distributions of SARS-CoV-2 spike protein trimers on intact virions
Ke, Z.; Oton, J.; Qu, K.; Cortese, M.; Zila, V.; McKeane, L.; Nakane, T.; Zivanov, J.; Neufeldt, C. J.; Lu, J. M.; Peukes, J.; Xiong, X.; Krausslich, H.-G.; Scheres, S. H. W.; Bartenschlager, R.; Briggs, J. A. G.
10.1101/2020.06.27.174979 — microbiology — Posted on 2020-06-27
589 Modified Vaccinia Ankara Based SARS-CoV-2 Vaccine Expressing Full-Length Spike Induces Strong Neutralizing Antibody Response
Routhu, N. K.; Gangadhara, S.; Cheedarla, N.; Shiferaw, A.; Rahman, S. A.; Sahoo, A.; Shi, P.-Y.; Menachery, V. D.; Floyd, K.; Fischinger, S.; Atyeo, C.; Alter, G.; Suthar, M. S.; Amara, R. R.
10.1101/2020.06.27.175166 — immunology — Posted on 2020-06-27
590 Atlas and developmental dynamics of mouse DNase I hypersensitive sites
Breeze, C. E.; Lazar, J.; Mercer, T.; Halow, J.; Washington, I.; Lee, K.; Ibarrientos, S.; Castillo, A.; Neri, F.; Haugen, E.; Rynes, E.; Reynolds, A.; Bates, D.; Diegel, M.; Dunn, D.; Kaul, R.; Sandstrom, R.; Meuleman, W.; Bender, M. A.; Groudine, M.; Stamatoyannopoulos, J. A.
10.1101/2020.06.26.172718 — genomics — Posted on 2020-06-27
593 MAGIC: Mosaic Analysis by gRNA-Induced Crossing-over
Allen, S. E.; Koreman, G. T.; Sarkar, A.; Wang, B.; Wolfner, M. F.; Han, C.
10.1101/2020.06.26.174045 — genetics — Posted on 2020-06-27
594 Cortical Organoids Model Early Brain Development Disrupted by 16p11.2 Copy Number Variants in Autism
Urresti, J.; Zhang, P.; Moran-Losada, P.; Yu, N.-K.; Negraes, P. D.; Trujillo, C. A.; Antaki, D.; Amar, M.; Chau, K.; Pramod, A. B.; Diedrich, J.; Tejwani, L.; Romero, S.; Sebat, J.; Yates, J. R.; Muotri, A. R.; Iakoucheva, L. M.
10.1101/2020.06.25.172262 — neuroscience — Posted on 2020-06-27
595 Saliva sampling is an excellent option to increase the number of SARS CoV2 diagnostic tests in settings with supplies shortages
Moreno-Contreras, J.; Espinoza, M. A.; Sandoval-Jaime, C.; Cantu-Cuevas, M. A.; Baron-Olivares, H.; Ortiz-Orozco, O.; Munoz-Rangel, V. A.; Hernandez-de Jesus, M.; Eroza-Osorio, C. M.; Arias, C. F.; Lopez, S.
10.1101/2020.06.24.170324 — microbiology — Posted on 2020-06-27
596 Binding Ability Prediction between Spike Protein and Human ACE2 Reveals the Adaptive Strategy of SARS-CoV-2 in Humans
Xue, X.; Shi, J.; Xu, H.; Qin, Y.; Yang, Z.; Feng, S.; Liu, D.; Jian, L.; Hua, L.; Wang, Y.; Zhang, Q.; Huang, X.; Zhang, X.; Li, X.; Chen, C.; Guo, J.; Tang, W.; Liu, J.
10.1101/2020.06.25.170704 — microbiology — Posted on 2020-06-27
597 bioPROTACs establish RAS as a degradable target and provide novel RAS biology insights
Lim, S.; Khoo, R.; Juang, Y.-C.; Gopal, P.; Zhang, H.; Yeo, C.; Peh, K. M.; Teo, J.; Ng, S.; Henry, B.; Partridge, A. W.
10.1101/2020.06.26.174565 — cancer biology — Posted on 2020-06-27
598 Requirement for PKC epsilon in KRAS-driven lung tumorigenesis
Garg, R.; Cooke, M.; Wang, S.; Benavides, F.; Abba, M. C.; Cicchini, M.; Feldser, D. M.; Kazanietz, M. G.
10.1101/2020.06.26.173690 — cancer biology — Posted on 2020-06-27
599 Dramatic shape changes occur as Cytochrome c folds
Kirmizialtin, S.; Pitici, F.; Cardenas, A.; Elber, R.; Thirumalai, D.
10.1101/2020.06.25.171926 — biophysics — Posted on 2020-06-27
601 Protein Contact Map Denoising Using Generative Adversarial Networks
Maddhuri Venkata Subramaniya, S. R.; Terashi, G.; Jain, A.; Kagaya, Y.; Kihara, D.
10.1101/2020.06.26.174300 — bioinformatics — Posted on 2020-06-27
602 Charge Interactions in a Highly Charge-depleted Protein
Hervo-Hansen, S.; Hojgaard, C.; Johansson, K. E.; Wang, Y.; Wahni, K.; Young, D.; Messens, J.; Teilum, K.; Lindorff-Larsen, K.; Winther, J. R.
10.1101/2020.06.26.173278 — biochemistry — Posted on 2020-06-27
603 Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes
Kozak, R. P.; Mondragon-Shem, K.; Williams, C.; Rose, C.; Perally, S.; Caljon, G.; van den abbeele, J.; Wongtrakul-Kish, K.; Gardner, R.; Spencer, D.; Lehane, M. J.; Acosta-Serrano, A.
10.1101/2020.06.25.172007 — biochemistry — Posted on 2020-06-27
604 DeepFRET: Rapid and automated single molecule FRET data classification using deep learning
Thomsen, J.; Sletfjerding, M. B.; Stella, S.; Paul, B.; Jensen, S. B.; Malle, M. G.; Petersen, T.; Montoya, G.; Hatzakis, N. S.
10.1101/2020.06.26.173260 — biophysics — Posted on 2020-06-27
605 Illuminating a Phytochrome Paradigm - a Light-Activated Phosphatase in Two-Component Signaling Uncovered
Multamäki, E.; Nanekar, R.; Morozov, D.; Lievonen, T.; Golonka, D.; Yuan Wahlgren, W.; Stucki-Buchli, B.; Rossi, J.; Hytönen, V. P.; Westenhoff, S.; Ihalainen, J. A.; Möglich, A.; Takala, H.
10.1101/2020.06.26.173310 — biochemistry — Posted on 2020-06-27
606 p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis
Mbouombouo Mfossa, A. C.; Verslegers, M.; Verreet, T.; Fida, H. B.; Mysara, M.; van IJcken, W.; De Vos, W. H.; Moons, L.; Baatout, S.; Benotmane, M. A.; Huylebroeck, D.; Quintens, R.
10.1101/2020.06.26.171132 — neuroscience — Posted on 2020-06-27
607 Gray matter covariations and core symptoms of autism. The EU-AIMS Longitudinal European Autism Project
Mei, T.; Llera, A.; Floris, D. L.; Forde, N. J.; Tillmann, J.; Durston, S.; Moessnang, C.; Banaschewski, T.; Holt, R. J.; Baron-Cohen, S.; Rausch, A.; Loth, E.; Dell'Acqua, F.; Charman, T.; Murphy, D. G. M.; Ecker, C.; Beckmann, C. F.; Buitelaar, J. K.; the EU-AIMS LEAP group,
10.1101/2020.06.26.171827 — neuroscience — Posted on 2020-06-27
608 Increased axon initial segment length results in increased Na+ currents in spinal motoneurones at symptom onset in the G127X SOD1 mouse model of Amyotrophic Lateral Sclerosis.
Jorgensen, H. S.; Jensen, D. B.; Dimintiyanova, K. P.; Bonnevie, V. S.; Hedegaard, A.; Lehnhoff, J.; Moldovan, M.; Grondahl, L. K.; Meehan, C. F.
10.1101/2020.06.25.096552 — neuroscience — Posted on 2020-06-27
609 Ectopic FGF23 production induces mineral changes, osteogenic transdifferentiation, and cancer associated microcalcifications
Boisen, I. M.; Nielsen, J. E.; Kaludjerovic, J.; O'Shaughnessy, P.; Kooij, I.; Toft, B. G.; Norman, R.; Ide, N.; Juul, A.; Andrews, P. W.; Smith, L. B.; Rajpert-De Meyts, E.; Lanske, B.; Blomberg Jensen, M.
10.1101/2020.06.25.171355 — molecular biology — Posted on 2020-06-27
614 The genome of North American beaver provides insights into the mechanisms of its longevity and cancer resistance
Zhang, Q.; Tombline, G.; Ablaeva, J.; Zhang, L.; Zhou, X.; Smith, Z.; Xiaoli, A. M.; Wang, Z.; Lin, J.-R.; Jabalameli, M. R.; Mitra, J.; Nguyen, N.; Vijg, J.; Seluanov, A.; Gladyshev, V. N.; Gorbunova, V.; Zhang, Z. D.
10.1101/2020.06.25.171322 — genomics — Posted on 2020-06-27
620 Mutation Maker, An Open Source Oligo Design Software for Mutagenesis and De Novo Gene Synthesis Experiments
Hiraga, K.; Mejzlik, P.; Marcisin, M.; Vostrosablin, N.; Gromek, A.; Arnold, J.; Wiewiora, S.; Svarba, R.; Prihoda, D.; Clarova, K.; Klempir, O.; Navratil, J.; Tupa, O.; Vazquez-Otero, A.; Walas, M. W.; Holy, L.; Spale, M.; Kotowski, J.; Dzamba, D.; Temesi, G.; Russell, J. H.; Marshall, N. M.; Bitton, D. A.
10.1101/2020.06.26.171819 — bioinformatics — Posted on 2020-06-27
621 Expansin-controlled cell wall stiffness regulates root growth in Arabidopsis
Samalova, M.; Elsayad, K.; Melnikava, A.; Peaucelle, A.; Gahurova, E.; Gumulec, J.; Spyroglou, I.; Zemlyanskaya, E. V.; Ubogoeva, E. V.; Hejatko, J.
10.1101/2020.06.25.170969 — plant biology — Posted on 2020-06-27
622 Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes
Alfradique-Dunham, I.; Al-Ouran, R.; von Coelln, R.; Blauwendraat, C.; Hill, E.; Luo, L.; Stillwell, A.; Young, E.; Tan, M.; Liao, C.; Hernandez, D.; Pihlstrom, L.; Grosset, D.; Shulman, L. M.; Liu, Z.; Rouleau, G.; International Parkinson's Disease Genomics Consortium, ; Nalls, M. A.; Singleton, A.; Morris, H.; Jankovic, J.; Shulman, J. M.
10.1101/2020.06.26.174276 — genomics — Posted on 2020-06-27
625 Order and disorder - an integrative structure of the full-length human growth hormone receptor
Kassem, N.; Araya-Secchi, R.; Bugge, K.; Barclay, A.; Steinocher, H.; Khondker, A.; Lenard, A. J.; Bürck, J.; Ulrich, A. S.; Pedersen, M. C.; Wang, Y.; Rheinstädter, M. C.; Pedersen, P. A.; Lindorff-Larsen, K.; Arleth, L.; Kragelund, B. B.
10.1101/2020.06.25.171116 — biophysics — Posted on 2020-06-27
628 Artificial Neural Networks Accurately Predict Language Processing in the Brain
Schrimpf, M.; Blank, I. A.; Tuckute, G.; Kauf, C.; Hosseini, E. A.; KANWISHER, N. G.; Tenenbaum, J. B.; Fedorenko, E.
10.1101/2020.06.26.174482 — neuroscience — Posted on 2020-06-27
629 A neural surveyor in somatosensory cortex
Miller, L.; Fabio, C.; van Beers, R.; Farne, A.; Medendorp, W. P.
10.1101/2020.06.26.173419 — neuroscience — Posted on 2020-06-27
631 Dopachrome tautomerase variants in patients with oculocutaneous albinism.
Pennamen, P.; Tingaud-Sequeira, A.; Gazova, I.; Keighren, M.; McKie, L.; Marlin, S.; Gherbi Halem, S.; Kaplan, J.; Delevoye, C.; Lacombe, D.; Plaisant, C.; Michaud, V.; Lasseaux, E.; Javerzat, S.; Jackson, I.; Arveiler, B.
10.1101/2020.06.26.171223 — genetics — Posted on 2020-06-27
633 Different tertiary interactions create the same important 3-D features in a divergent flavivirus xrRNA
Jones, R. A.; Steckelberg, A.-L.; Szucs, M. J.; Akiyama, B. M.; Vicens, Q.; Kieft, J. S.
10.1101/2020.06.25.172429 — biochemistry — Posted on 2020-06-27
636 Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis
Ma, D.; Hernandez, G. A.; Lefebvre, A. E. Y. T.; Alshetaiwi, H.; Blake, K.; Dave, K. R.; Rauf, M.; Williams, J. W.; Davis, R. T.; Evans, K. T.; Masoud, M. Y. G.; Lee, R.; Edwards, R. A.; Digman, M. A.; Kessenbrock, K.; Lawson, D. A.
10.1101/2020.06.25.172056 — cancer biology — Posted on 2020-06-27
639 Mass-spectrometry-based near complete draft of the Saccharomyces cerevisiae proteome
Gao, Y.; Ping, L.; Duong, D.; Zhang, C.; Dammer, E. B.; Li, Y.; Chen, P.; Chang, L.; Gao, H.; Wu, J.; Xu, P.
10.1101/2020.06.24.168526 — biochemistry — Posted on 2020-06-27
642 Evaluation of Seed or Grain Storage Technologies from Indian Farming Societies Using A Hybrid and Multi-Attribute Approach
Maity, A.; Mukherjee, A.; Ray, M.; Pramanik, P.; Parmar, S. S.; N, M.; Kumar, S.; Wasnik, V. K.; Kumari, S.
10.1101/2020.06.25.172189 — plant biology — Posted on 2020-06-27
643 GDSL-domain containing proteins mediate suberin biosynthesis and degradation, enabling developmental plasticity of the endodermis during lateral root emergence
Ursache, R.; De Jesus Vieira Teixeira, C.; Denervaud Tendon, V.; Gully, K.; De Bellis, D.; Schmid-Siegert, E.; Grube Andersen, T.; Shekhar, V.; Calderon, S.; Pradervand, S.; Nawrath, C.; Geldner, N.; Vermeer, J. E. M.
10.1101/2020.06.25.171389 — plant biology — Posted on 2020-06-27
647 PCNA-K164 ubiquitination facilitates origin licensing and mitotic DNA synthesis
Leung, W.; Baxley, R. M.; Thakar, T.; Rogers, C. B.; Buytendorp, J. P.; Wang, L.; Tella, A.; Moldovan, G.-L.; Shima, N.; Bielinsky, A. K.
10.1101/2020.06.25.172361 — molecular biology — Posted on 2020-06-27
648 WNT6-ACC2-induced accumulation of triacylglycerol rich lipid droplets is exploited by Mycobacterium tuberculosis
Brandenburg, J.; Marwitz, S.; Tazoll, S. C.; Waldow, F.; Kalsdorf, B.; Vierbuchen, T.; Scholzen, T.; Gross, A.; Goldenbaum, S.; Hoelscher, A.; Hein, M.; Linnemann, L.; Reimann, M.; Kispert, A.; Leitges, M.; Rupp, J.; Lange, C.; Niemann, S.; Behrends, J.; Goldmann, T.; Heine, H.; Schaible, U. E.; Hoelscher, C.; Schwudke, D.; Reiling, N.
10.1101/2020.06.26.174110 — immunology — Posted on 2020-06-26
652 IRRIGATION WATER DEPTHS AND SOIL COVERS IN CARROT CROP
Vieira, J. H.; Aleman, C. C.; de Freitas, E. M.; Santos, L. d. A.; Da Silva, G. H.; Fernandes, P. H. F.
10.1101/2020.05.13.094128 — ecology — Posted on 2020-06-27
654 Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite
Perez, M.; Bak, D. W.; Bergholtz, S. E.; Crooks, D. R.; Yang, Y.; Linehan, W. M.; Weerapana, E.; Meier, J. L.
10.1101/2020.06.25.171843 — cancer biology — Posted on 2020-06-26
656 An in vitro human-based fracture gap model - Mimicking the crosstalk between bone and immune cells
Pfeiffenberger, M.; Damerau, A.; Ponomarev, I.; Bucher, C. H.; Chen, Y.; Barnewitz, D.; Thoene-Reineke, C.; Hoff, P.; Buttgereit, F.; Gaber, T.; Lang, A.
10.1101/2020.06.26.165456 — bioengineering — Posted on 2020-06-27
659 HLH-30 dependent rewiring of metabolism during starvation in C. elegans
Dall, K. B.; Havelund, J. F.; Harvald, E. B.; Witting, M.; Faergeman, N. J.
10.1101/2020.06.26.170555 — biochemistry — Posted on 2020-06-26
663 Cold tolerance of mountain stoneflies (Plecoptera: Nemouridae) from the high Rocky Mountains
Hotaling, S.; Shah, A. A.; Dillon, M. E.; Giersch, J. J.; Tronstad, L. M.; Finn, D. S.; Woods, H. A.; Kelley, J. L.
10.1101/2020.06.25.171934 — physiology — Posted on 2020-06-26
668 Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens
Numberger, D.; Zoccarato, L.; Woodhouse, J.; Ganzert, L.; Sauer, S.; Grossart, H.-P.; Greenwood, A. D.
10.1101/2020.06.26.173328 — microbiology — Posted on 2020-06-26
671 Aging leads to stochastic loss of silencing at transposons in mammary luminal epithelial cells
Senapati, P.; Miyano, M.; Basam, M.; Sayaman, R. W.; Leung, A.; LaBarge, M. A.; Schones, D. E.
10.1101/2020.06.26.170043 — genomics — Posted on 2020-06-26
673 Transgressive segregation for salt tolerance in rice due to physiological coupling and uncoupling and genetic network rewiring
de los Reyes, B. G.; Pabuayon, I. C.; KItazumi, A.; Cushman, K. R.; Singh, R. K.; Gregorio, G. B.; Dhatt, B. K.; Zabet-Moghaddam, M.; Walia, H.
10.1101/2020.06.25.171603 — genetics — Posted on 2020-06-26
674 Bi-compartmentalized stem cell organization of the corneal limbal niche
Rompolas, P.; Farrelly, O.; Suzuki-Horiuchi, Y.; Brewster, M.; Kuri, P.; Huang, S.; Rice, G.; Xu, J.; Dentchev, T.; Lee, V.
10.1101/2020.06.25.171462 — developmental biology — Posted on 2020-06-26
675 Epigenetic regulations follow cell cycle progression during differentiation of human pluripotent stem cells.
Madrigal, P.; Pauklin, S.; Jee Goh, K.; Grandy, R.; Osnato, A.; Ortmann, D.; Vallier, L.; Brown, S.
10.1101/2020.06.26.173211 — cell biology — Posted on 2020-06-26
677 A single cell atlas of the healthy breast tissues reveal clinically relevant clusters of breast epithelial cells
Bhat-Nakshatri, P.; Gao, H.; McGuire, P. C.; Xuei, X.; Liu, S.; Wan, J.; Liu, Y.; Althouse, S. K.; Colter, A.; Sandusky, G.; Storniolo, A. M.; Nakshatri, H.
10.1101/2020.06.25.171793 — cancer biology — Posted on 2020-06-26
678 Direct Supercritical Angle Localization Microscopy for Nanometer 3D Superresolution
Dasgupta, A.; Deschamps, J.; Matti, U.; Huebner, U.; Becker, J.; Strauss, S.; Jungmann, R.; Heintzmann, R.; Ries, J.
10.1101/2020.06.25.171058 — biophysics — Posted on 2020-06-26
680 Multicompartmental Non-invasive Sensing of Postprandial Lipemia in Humans with Multispectral Optoacoustic Tomography
Fasoula, N.-A.; Karlas, A.; Kallmayer, M.; Milik, A. B.; Pelisek, J.; Eckstein, H.-H.; Klingenspor, M.; Ntziachristos, V.
10.1101/2020.06.25.171413 — bioengineering — Posted on 2020-06-26
681 Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of the gene regulatory program in cancers
Castro-Mondragon, J. A.; Aure, M. R.; Lingaerde, O. C.; Langerod, A.; Martens, J. W. M.; Borresen-Dale, A.-L.; Kristensen, V.; Mathelier, A.
10.1101/2020.06.25.170738 — genomics — Posted on 2020-06-26
687 The Nucleus is a Quality Control Center For Non-Imported Mitochondrial Proteins
Shakya, V. P. S.; Barbeau, W. A.; Xiao, T.; Knutson, C. S.; Hughes, A. L.
10.1101/2020.06.26.173781 — cell biology — Posted on 2020-06-26
688 Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance
Li, L.; Lin, L.; Veeraraghavan, J.; Hu, Y.; Wang, X.; Lee, S.; Tan, Y.; Schiff, R.; wang, x.
10.1101/2020.06.26.149948 — cancer biology — Posted on 2020-06-26
689 Deep Learning for Virtual Screening: Five Reasons to Use ROC Cost Functions
Golkov, V.; Becker, A.; Plop, D. T.; Cuturilo, D.; Davoudi, N.; Mendenhall, J.; Moretti, R.; Meiler, J.; Cremers, D.
10.1101/2020.06.25.166884 — pharmacology and toxicology — Posted on 2020-06-26
691 Germline gene de-silencing by a transposon insertion is triggered by an altered landscape of local piRNA biogenesis
Miller, D.; Van Vaerenberghe, K.; Li, A.; Grantham, E. K.; Cummings, C.; Barragan, M.; Egidy, R.; Scott, A. R.; Hall, K.; Perera, A.; Gilliland, W. D.; Blumenstiel, J. P.
10.1101/2020.06.26.173187 — genetics — Posted on 2020-06-26
692 Activation of the Integrated Stress Response in drug-tolerant melanoma cells confers vulnerability to mitoribosome-targeting antibiotics.
Konnova, A.; Vendramin, R.; Adnane, S.; Cinque, S.; Katopodi, V.; Knezevic, Z.; Karras, P.; Demesmaeker, E.; Bosisio, F. M.; Rizzotto, L.; Bechter, O.; Marine, J.-C.; Leucci, E.
10.1101/2020.06.26.173492 — cancer biology — Posted on 2020-06-26
696 Cheetah: a computational toolkit for cybergenetic control
Pedone, E.; de Cesare, I.; Zamora, C.; Haener, D.; Postiglione, L.; Shannon, B.; Savery, N.; Grierson, C. S.; di Barnardo, M.; Gorochowski, T. E.; Marucci, L.
10.1101/2020.06.25.171751 — synthetic biology — Posted on 2020-06-26
698 Modification of streptococcal cell wall polysaccharide spatially controls cell division
Zamakhaeva, S.; Chaton, C. T.; Rush, J. S.; Ajay Castro, S.; Yarawsky, A. E.; Herr, A. B.; van Sorge, N. M.; Dorfmueller, H. C.; Frolenkov, G. I.; Korotkov, K. V.; Korotkova, N.
10.1101/2020.06.26.173716 — microbiology — Posted on 2020-06-26
701 Spatial Variation of Microtubule Depolymerization in Large Asters Suggests Regulation by MAP Depletion
Ishihara, K.; Decker, F.; Caldas, P.; Pelletier, J.; Loose, M.; Brugues, J.; Mitchison, T.
10.1101/2020.06.26.172783 — cell biology — Posted on 2020-06-26
702 TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS
Cunningham, K. M.; Zhang, K.; Ruan, K.; Maulding, K.; Senturk, M.; Grima, J.; Sung, H.; Zuo, Z.; Song, H.; Rothstein, J. D.; Bellen, H. J.; Lloyd, T.
10.1101/2020.06.26.173021 — cell biology — Posted on 2020-06-26
703 Air and surface measurements of SARS-CoV-2 inside a bus during normal operation
Di Carlo, P.; Chiacchiaretta, P.; Sinjari, B. d.; Aruffo, E.; Stuppia, L.; De Laurenzi, V.; Di Tomo, P.; Pelusi, L.; Potenza, F.; Veronese, A.; Vecchiet, J.; Falasca, K.; Ucciferri, C.
10.1101/2020.06.26.173146 — biochemistry — Posted on 2020-06-26
707 A new plant-specific syntaxin-6 protein contributes to the intracytoplasmic route for begomoviruses
Gouveia-Mageste, B. C.; Martins, L. G. C.; Dal-Bianco, M.; Machado, J. P. B.; Silva, J. C. F.; Kim, A. Y.; Yazaki, J.; Santos, A. A.; Ecker, J. R.; Fontes, E. P. B.
10.1101/2020.01.10.901496 — plant biology — Posted on 2020-06-26
708 Functional reorganization of brain networks across the human menstrual cycle
Pritschet, L.; Santander, T.; Taylor, C. M.; Layher, E.; Yu, S.; Miller, M. B.; Grafton, S. T.; Jacobs, E. G.
10.1101/866913 — neuroscience — Posted on 2020-06-26
709 Does hippocampal volume explain performance differences on hippocampal-dependent tasks?
Clark, I. A.; Monk, A. M.; Hotchin, V.; Pizzamiglio, G.; Liefgreen, A.; Callaghan, M. F.; Maguire, E. A.
10.1101/2020.04.29.067611 — neuroscience — Posted on 2020-06-26
710 The Aging Slow Wave: A Shifting Amalgam of Distinct Slow Wave and Spindle Coupling Subtypes Define Slow Wave Sleep Across the Human Lifespan
McConnell, B. V.; Kronberg, E.; Teale, P. D.; Fishback, G. M.; Kaplan, R. I.; Sillau, S. H.; Fought, A. J.; Dhanasekaran, A. R.; Berman, B. D.; Ramos, A. R.; McClure, R. L.; Bettcher, B. M.
10.1101/2020.05.28.122168 — neuroscience — Posted on 2020-06-26
711 Evaluating aerosol and splatter following dental procedures
Allison, J.; Currie, C.; Edwards, D.; Bowes, C.; Coulter, J.; Pickering, K.; Kozhevnikova, E.; Durham, J.; Nile, C.; Jakubovics, N.; Rostami, N.; Holliday, R.
10.1101/2020.06.25.154401 — microbiology — Posted on 2020-06-26
712 BATF3-dependent induction of IL-27 by B cells bridges the innate and adaptive stages of the antibody response
Yan, H.; Wang, R.; Wang, J.; Wu, S.; Fernandez, M.; Rivera, C. E.; Moroney, J. B.; Li, X.; Zhang, N.; Zan, H.; Meng, X.; Zhang, F.; Zheng, S.; Chen, Y.; Yin, Z.; Kedl, R.; Min, B.; Hunter, C. A.; Xiang, Y.; Casali, P.; Xu, Z.
10.1101/2020.06.26.117010 — immunology — Posted on 2020-06-26
713 Nfkbid is required for immunity and antibody responses to Toxoplasma gondii
Souza, S. P.; Splitt, S. D.; Alvarez, J. A.; Wizzard, S.; Wilson, J.; Luo, Z.; Baumgarth, N.; Jensen, K.
10.1101/2020.06.26.174151 — immunology — Posted on 2020-06-26
716 An exon DNA element modulates heterochromatin spreading in the master regulator for sexual commitment in malaria parasites
Cordon-Obras, C.; Barcons-Simon, A.; Scheidig- Benatar, C.; Claes, A.; Sabatet, V.; Loew, D.; Scherf, A.
10.1101/2020.06.26.163105 — genetics — Posted on 2020-06-26
717 Population Bottlenecks and Intra-host Evolution during Human-to-Human Transmission of SARS-CoV-2Population Bottlenecks and Intra-host Evolution during Human-to-Human Transmission of SARS-CoV-2
Wang, D.; Wang, Y.; Sun, W.; Zhang, L.; Ji, J.; Zhang, Z.; Cheng, X.; Li, Y.; Xiao, F.; Zhu, A.; Zhong, B.; Ruan, S.; Li, J.; Ren, P.; Ou, Z.; Xiao, M.; Li, M.; Deng, Z.; Zhong, H.; Li, F.; Chen, W.; Zhu, S.; Wang, W.; Zhang, Y.; Xu, X.; Jin, X.; Zhao, J.; Zhong, N.; Zhang, W.; Zhao, J.; Li, J.; Xu, Y.
10.1101/2020.06.26.173203 — genetics — Posted on 2020-06-26
721 The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa
Brandel, A.; Aigal, S.; Lagies, S.; Schlimpert, M.; Lehmann, A.; Hummel, D.; Fisch, D.; Melendez, A. V.; Madl, J.; Eierhoff, T.; Kammerer, B.; Roemer, W.
10.1101/2020.06.26.173336 — cell biology — Posted on 2020-06-26
722 Structure of the Bacterial Ribosome at 2 A Resolution
Watson, Z. L.; Ward, F. R.; Meheust, R.; Ad, O.; Schepartz, A.; Banfield, J.; Cate, J. H. D.
10.1101/2020.06.26.174334 — biophysics — Posted on 2020-06-26
723 GENERATION OF HEART ORGANOIDS MODELING EARLY HUMAN CARDIAC DEVELOPMENT UNDER DEFINED CONDITIONS
Israeli, Y.; Gabalski, M.; Ball, K.; Wasserman, A.; Zou, J.; Ni, G.; Zhou, C.; Aguirre, A.
10.1101/2020.06.25.171611 — bioengineering — Posted on 2020-06-26
729 Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in wildtype and cloche/npas4l mutant zebrafish embryos
McGarvey, A. C.; Kopp, W.; Vucicevic, D.; Kempfer, R.; Mattonet, K.; Hirsekorn, A.; Bilic, I.; Trinks, A.; Merks, A. M.; Panáková, D.; Pombo, A.; Akalin, A.; Junker, J. P.; Stainier, D. Y. R.; Garfield, D.; Ohler, U.; Lacadie, S. A.
10.1101/2020.06.26.173377 — genomics — Posted on 2020-06-26
733 More than noise: Context-dependant luminance contrast discrimination in a coral reef fish (Rhinecanthus aculeatus)
van den Berg, C.; Hollenkamp, M.; Mitchell, L. J.; Watson, E. J.; Green, N. F.; Marshall, N. J.; Cheney, K. L.
10.1101/2020.06.25.168443 — animal behavior and cognition — Posted on 2020-06-26
736 Proteomic data from leaves of twenty-four sunflower genotypes underwater deficit
Balliau, T.; Durufle, H.; Blanchet, N.; Blein-Nicolas, M.; Langlade, N. B.; Zivy, M.
10.1101/2020.06.26.171066 — plant biology — Posted on 2020-06-26
745 Using a centrifuge-based method to identify novel root traits that affect root-substrate adhesion in Arabidopsis thaliana
Eldridge, B. M.; Larson, E. R.; Weldon, L.; Smyth, K. M.; Sellin, A. N.; Chenchiah, I. V.; Liverpool, T. B.; Grierson, C. S.
10.1101/2020.05.14.095448 — plant biology — Posted on 2020-06-26
747 The interoceptive self contributes to preference stability
Azzalini, D.; Buot, A.; Palminteri, S.; Tallon-Baudry, C.
10.1101/776047 — neuroscience — Posted on 2020-06-26
750 Antibiotics effects on the fecal metabolome in preterm infants
Patton, L.; Li, N.; Garrett, T. J.; Ruoss, J. L.; Russell, J. T.; de la Cruz, D.; Bazacliu, C.; Polin, R. A.; Triplett, E. W.; Neu, J.
10.1101/2020.06.26.159590 — microbiology — Posted on 2020-06-26
751 Lack of mucosal cholinergic innervation is associated with increased risk of enterocolitis in Hirschsprung disease
Keck, S.; Galati-Fournier, V.; Kym, U.; Moesch, M.; Usemann, J.; Subotic, U.; Tharakan, S.; Krebs, T.; Stathopoulos, E.; Schmittenbecher, P.; Cholewa, D.; Romero, P.; Reingruber, B.; Bruder, E.; NIG Study Group, ; Holland-Cunz, S.
10.1101/2020.06.15.151621 — immunology — Posted on 2020-06-26
752 A catalog of homoplasmic and heteroplasmic mitochondrial DNA variants in humans
Bolze, A.; Mendez, F.; White, S.; Tanudjaja, F.; Isaksson, M.; Jiang, R.; Dei Rossi, A.; Cirulli, E. T.; Rashkin, M.; Metcalf, W. J.; Grzymski, J. J.; Lee, W.; Lu, J.; Washington, N. L.
10.1101/798264 — genetics — Posted on 2020-06-26
754 3D Visualization of Macromolecule Synthesis
Duerr, T. J.; Comellas, E.; Jeon, E. K.; Farkas, J. E.; Joetzjer, M.; Garnier, J.; Shefelbine, S. J.; Monaghan, J. R.
10.1101/2020.06.24.169300 — developmental biology — Posted on 2020-06-26
755 Distinct photooxidation-induced cell death pathways lead to selective killing of human breast cancer cells
dos Santos, A. F.; Inague, A.; Arini, G. S.; Terra, L. F.; Wailemann, R. A. M.; Pimentel, A. C. P. C.; Yoshinaga, M. Y.; Silva, R. R. S. R.; Severino, D.; de Almeida, D. R. Q.; Gomes, V. M.; Bruni-Cardoso, A.; Terra, W. R.; Miyamoto, S.; Baptista, M. S.; Labriola, L.
10.1101/2020.06.25.170860 — cancer biology — Posted on 2020-06-26
758 Nicotinamide Riboside supplementation does not alter whole-body or skeletal muscle metabolic responses to a single bout of endurance exercise
Stocks, B.; Ashcroft, S. P.; Joanisse, S.; Elhassan, Y.; lavery, G. G.; Dansereau, L. C.; Philp, A. M.; Wallis, G. A.; Philp, A.
10.1101/2020.06.23.143446 — physiology — Posted on 2020-06-26
761 Human brain function during pattern separation follows hippocampal and neocortical connectivity gradients
Li, Q.; Tavakol, S.; Royer, J.; Lariviere, S.; Vos de Wael, R.; Park, B.-y.; Paquola, C.; Caldairou, B.; Bassett, D. S.; Bernasconi, A.; Bernasconi, N.; Frauscher, B.; Smallwood, J.; Caciagli, L.; Li, S.; Bernhardt, B.
10.1101/2020.06.22.165290 — neuroscience — Posted on 2020-06-26
765 Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p
Tong, Y.; Sun, N.; Wang, X.; Wei, Q.; Zhang, Y.; Huang, R.; Pu, Y.; Dai, H.; Ren, B.; Pei, G.; Song, F.; Zhu, G.; Wang, X.; Xia, X.; Chen, X.; Jiang, L.; Zhang, J.; Ouyang, L.; Zhang, B.; Jiang, Y.; Liu, X.; Calderone, R.; Bai, F.; Zhang, L.; Alterovitz, G.
10.1101/2020.06.26.173484 — microbiology — Posted on 2020-06-26
766 The infection cushion: a fungal weapon of plant-biomass destruction
Choquer, M.; Rascle, C.; Goncalves, I.; de Vallee, A.; Ribot, C.; Loisel, E.; Smilevski, P.; Ferria, J.; Savadogo, M.; Souibgui, E.; Gagey, M.-J.; Dupuy, J.-W.; Rollins, J. A.; Marcato, R.; Nous, C.; Bruel, C.; Poussereau, N.
10.1101/2020.06.26.173369 — microbiology — Posted on 2020-06-26
767 Postnatal expansion, maturation and functionality of MR1 T cells in humans
Swarbrick, G. M.; Gela, A.; Cansler, M. E.; Null, M. D.; Duncan, R. B.; Nemes, E.; Shey, M.; Nsereko, M.; Mayanja-Kizza, H.; Kiguli, S.; Koh, J.; Hanekom, W.; Hatherill, M.; Lancioni, C.; Lewinsohn, D. M.; Scriba, T.; Lewinsohn, D. A.
10.1101/2019.12.20.882746 — immunology — Posted on 2020-06-26
770 Modelling Subject Variability in the Spatial and Temporal Characteristics of Functional Modes
Harrison, S. J.; Bijsterbosch, J. D.; Segerdahl, A. R.; Fitzgibbon, S. P.; Farahibozorg, S.-R.; Duff, E.; Smith, S. M.; Woolrich, M. W.
10.1101/544817 — neuroscience — Posted on 2020-06-26
771 Prion protein lowering is a disease-modifying therapy across prion strains, disease stages, and endpoints
Minikel, E. V.; Zhao, H. T.; Le, J.; O'Moore, J.; Pitstick, R.; Graffam, S.; Carlson, G. A.; Kavanaugh, M. P.; Kriz, J.; Kim, J. B.; Ma, J.; Wille, H.; Aiken, J.; McKenzie, D.; Doh-ura, K.; Beck, M.; O'Keefe, R.; Stathopoulos, J.; Caron, T.; Schreiber, S. L.; Carroll, J. B.; Kordasiewicz, H. B.; Cabin, D. E.; Vallabh, S. M.
10.1101/2020.03.27.011940 — neuroscience — Posted on 2020-06-26
774 Ag nanoparticles-based antimicrobial polycotton fabrics to prevent the transmission and spread of SARS-CoV-2
Tremiliosi, G. C.; Simoes, L. G. P.; Minozzi, D. T.; Santos, R. I.; Vilela, D. B.; Durigon, E. L.; Machado, R. R. G.; Medina, D. S.; Ribeiro, L. K.; Rosa, I. L. V.; Assis, M.; Bort, J. M. A.; Longo, E.; Freitas-Junior, L. H.
10.1101/2020.06.26.152520 — microbiology — Posted on 2020-06-26
780 Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor
Zhao, P.; Praissman, J. L.; Grant, O. C.; Cai, Y.; Xiao, T.; Rosenbalm, K. E.; Aoki, K.; Kellman, B. P.; Bridger, R.; Barouch, D. H.; Brindley, M. A.; Lewis, N. E.; Tiemeyer, M.; Chen, B.; Woods, R. J.; Wells, L.
10.1101/2020.06.25.172403 — biochemistry — Posted on 2020-06-26
781 Resource optimization in COVID-19 diagnosis
Taniwaki, S. A.; Silva, S. O. S.; Santana-Clavijo, N. F.; Conselheiro, J. A.; Barone, G. T.; Menezes, A. A. R.; Pereira, E. S.; Brandao, P. E.
10.1101/2020.06.25.172528 — molecular biology — Posted on 2020-06-26
782 Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2
Kim, Y.; Wower, J.; Maltseva, N.; Chang, C.; Jedrzejczak, R.; Wilamowski, M.; Kang, S.; Nicolaescu, V.; Randall, G.; Michalska, K.; Joachimiak, A.
10.1101/2020.06.26.173872 — molecular biology — Posted on 2020-06-26
783 Nanotrap(R) particles improve detection of SARS-CoV-2 for pooled sample methods, extraction-free saliva methods, and extraction-free medium methods
Barclay, R. A.; Akhrymuk, I.; Patnaik, A.; Callahan, V.; Lehman, C.; Andersen, P.; Barbero, R.; Barksdale, S.; Dunlap, R.; Goldfarb, D.; Jones-Roe, T.; Kelly, R.; Kim, B.; Miao, S.; Munns, A.; Munns, D.; Patel, S.; Porter, E.; Ramsey, R.; Sahoo, S.; Swahn, O.; Warsh, J.; Kehn-Hall, K.; Lepene, B.
10.1101/2020.06.25.172510 — microbiology — Posted on 2020-06-26
784 Swarm Learning as a privacy-preserving machine learning approach for disease classification
Warnat-Herresthal, S.; Schultze, H.; Shastry, K. P. L.; Manamohan, S.; Mukherjee, S.; Garg, V.; Sarveswara, R.; Haendler, K.; Pickkers, P.; Aziz, N. A.; Ktena, S.; Siever, C.; Kraut, M.; Desai, M.; Monet, B.; Saridaki, M.; Siegel, C. M.; Drews, A.; Nuesch-Germano, M.; Theis, H.; Netea, M. G.; Theis, F. J.; Aschenbrenner, A. C.; Ulas, T.; Breteler, M. M. B.; Giamarellos-Bourboulis, E. J.; Kox, M.; Becker, M.; Cheran, S.; Woodacre, M. S.; Goh, E. L.; Schultze, J. L.; German COVID-19 OMICS Initiative (DeCOI),
10.1101/2020.06.25.171009 — bioinformatics — Posted on 2020-06-26
785 Evaluation of K18-hACE2 mice as a model of SARS-CoV-2 infection
Moreau, G. B.; Burgess, S. L.; Sturek, J. M.; Donlan, A. N.; Petri, W. A.; Mann, B. J.
10.1101/2020.06.26.171033 — pathology — Posted on 2020-06-26
786 In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
Turonova, B.; Sikora, M.; Schürmann, C.; Hagen, W. J. H.; Welsch, S.; Blanc, F. E. C.; von Bülow, S.; Gecht, M.; Bagola, K.; Hörner, C.; van Zandbergen, G.; Mosalaganti, S.; Schwarz, A.; Covino, R.; Mühlebach, M. D.; Hummer, G.; Krijnse Locker, J.; Beck, M.
10.1101/2020.06.26.173476 — molecular biology — Posted on 2020-06-26
787 Neuroinvasive potential of SARS-CoV-2 revealed in a human brain organoid model
Song, E.; Zhang, C.; Israelow, B.; Lu, P.; Weizman, O.-E.; Liu, F.; Dai, Y.; Szigeti-Buck, K.; Yasumoto, Y.; Wang, G.; Heltke, J.; Ng, E.; Wheeler, J.; Alfajaro, M. M.; Fontes, B.; Ravindra, N.; van Dijk, D.; Mane, S.; Gunel, M.; Ring, A.; Wilen, C. B.; Horvath, T.; LOUVI, A.; Farhadian, S.; Bilguvar, K.; Iwasaki, A.
10.1101/2020.06.25.169946 — microbiology — Posted on 2020-06-26
788 Development of a Coronavirus Disease 2019 Nonhuman Primate Model Using Airborne Exposure
Johnston, S. C.; Jay, A.; Raymond, J. L.; Rossi, F.; Zeng, X.; Scruggs, J.; Dyer, D.; Frick, O.; Moore, J.; Berrier, K.; Esham, H.; Shamblin, J.; Sifford, W.; Fiallos, J.; Klosterman, L.; Stevens, S.; White, L.; Bowling, P.; Garcia, T.; Jensen, C.; Ghering, J.; Nyakiti, D.; Bellanca, S.; Kearney, B.; Giles, W.; Alli, N.; Paz, F.; Akers, K.; Danner, D.; Barth, J.; Johnson, J.; Durant, M.; Kim, R.; Pitt, M. L.; Nalca, A.
10.1101/2020.06.26.174128 — microbiology — Posted on 2020-06-26
790 Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation
Henderson, R.; Edwards, R. J.; Mansouri, K.; Janowska, K.; Stalls, V.; Kopp, M.; Haynes, B. F.; Acharya, P.
10.1101/2020.06.26.173765 — biophysics — Posted on 2020-06-26
791 Naturally mutated spike proteins of SARS-CoV-2 variants show differential levels of cell entry
Ozono, S.; Zhang, Y.; Ode, H.; Tan, T. S.; Imai, K.; Miyoshi, K.; Kishigami, S.; Ueno, T.; Iwatani, Y.; Suzuki, T.; Tokunaga, K.
10.1101/2020.06.15.151779 — microbiology — Posted on 2020-06-26
794 Lineage recording reveals dynamics of cerebral organoid regionalization
He, Z.; Gerber, T.; Maynard, A.; Jain, A.; Petri, R.; Santel, M.; Ly, K.; Sidow, L.; Sanchis-Calleja, F.; Riesenberg, S.; Camp, J. G.; Treutlein, B.
10.1101/2020.06.19.162032 — developmental biology — Posted on 2020-06-26
797 Early cardiac inflammation as a driver of murine model of Arrhythmogenic Cardiomyopathy
Ng, K.-E.; Delaney, P. J.; Thenet, D.; Murtough, S.; Webb, C. M.; Tsisanova, E.; Walker, S. L.; Westaby, J. D.; Pennington, D. J.; Pink, R.; Kelsell, D. P.; Tinker, A.
10.1101/2020.06.24.169664 — immunology — Posted on 2020-06-26
798 Acquisition of hypoxia inducibility by oxygen sensing N-terminal cysteine oxidase in spermatophytes
Weits, D. A.; Zhou, L.; Giuntoli, B.; Dalle Carbonare, L.; Iacopino, S.; Piccinini, L.; Shukla, V.; Bui, L. T.; Novi, G.; van Dongen, J. T.; Licausi, F.
10.1101/2020.06.24.169417 — plant biology — Posted on 2020-06-26
799 Diversity of Antimicrobial-Resistant Aeromonas Species Isolated from Aquatic Environments in Brazil
Conte, D.; Palmeiro, J. K.; Bavaroski, A. A.; Rodrigues, L. S.; Cardozo, D.; Tomaz, A. P.; Camargo, J. O.; Dalla-Costa, L. M.
10.1101/2020.06.23.168385 — microbiology — Posted on 2020-06-26
800 Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis
Hofemeier, A. D.; Limon, T.; Muenker, T. M.; Wallmeyer, B.; Jurado, A.; Afshar, M. E.; Ebrahimi, M.; Gilbert, P. M.; Betz, T.
10.1101/2020.06.24.164988 — biophysics — Posted on 2020-06-26
802 A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies
Tiu, G. C.; Kerr, C. H.; Forester, C. M.; Krishnarao, P. S.; Rosenblatt, H. D.; Raj, N.; Zhulyn, O.; Bowen, M. E.; Shokat, L.; Attardi, L. D.; Ruggero, D.; Barna, M.
10.1101/2020.06.24.167940 — developmental biology — Posted on 2020-06-26
803 Modulation of motor behavior by the mesencephalic locomotor region
Dautan, D.; Kovacs, A.; Bayasgalan, T.; Diaz-Acevedo, M. A.; Pal, B.; Mena-Segovia, J.
10.1101/2020.06.25.172296 — neuroscience — Posted on 2020-06-26
804 Photoperiodic Effects on Monoamine Signaling & Gene Expression Throughout Development in the Serotonin & Dopamine Systems
Siemann, J. K.; Williams, P.; Malik, T. N.; Jackson, C.; Green, N. H.; Emeson, R.; Levitt, P.; McMahon, D. G.
10.1101/2020.06.25.171470 — neuroscience — Posted on 2020-06-26
812 Mass-spectrometry-based near complete draft of the Saccharomyces cerevisiae proteome
Xu, P.; Gao, Y.; Ping, L.; Duong, D.; Zhang, C.; Dammer, E. B.; Li, Y.; Chen, P.; Chang, L.; Gao, H.; Wu, J.
10.1101/2020.06.24.168526 — biochemistry — Posted on 2020-06-26
818 Modulation of ferroptosis sensitivity by TXNRD1 in pancreatic cancer cells
Cai, L. L.; Ruberto, R. A.; Ryan, M. J.; Eaton, J. K.; Schreiber, S. L.; Viswanathan, V. S.
10.1101/2020.06.25.165647 — cell biology — Posted on 2020-06-26
822 GENERATION OF HEART ORGANOIDS MODELING EARLY HUMAN CARDIAC DEVELOPMENT UNDER DEFINED CONDITIONS
Israeli, Y.; Gabalski, M.; Ball, K.; Wasserman, A.; Zou, J.; Ni, G.; Zhou, C.; Aguirre, A.
10.1101/2020.06.25.171611 — bioengineering — Posted on 2020-06-26
829 3D Visualization of Macromolecule Synthesis
Duerr, T. J.; Comellas, E.; Jeon, E. K.; Farkas, J. E.; Joetzjer, M.; Garnier, J.; Shefelbine, S. J.; Monaghan, J. R.
10.1101/2020.06.24.169300 — developmental biology — Posted on 2020-06-26
830 Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei
Amodeo, S.; Kalichava, A.; Fradera-Sola, A.; Bertiaux, E.; Guichard, P.; Butter, F.; Ochsenreiter, T.
10.1101/2020.06.25.171090 — cell biology — Posted on 2020-06-26
831 Efficient precise in vivo base editing in adult dystrophic mice
Xu, L.; Zhang, C.; Li, H.; Wang, P.; Gao, Y.; Mohler, P. J.; Mokadam, N.; Ma, J.; Arnold, W. D.; Han, R.
10.1101/2020.06.24.169292 — bioengineering — Posted on 2020-06-26
832 Custom-Designed, Degradation-Resistant Messenger RNAs in Yeast
Franklin, A. L.; Macfadden, A.; Kieft, J. G.; Hesselberth, J.; Chapman, E. G.
10.1101/2020.06.25.169177 — biochemistry — Posted on 2020-06-26
837 SWELL1-LRRC8 complex regulates skeletal muscle cell size, intracellular signalling, adiposity and glucose metabolism
Kumar, A.; Xie, L.; Ta, C. M.; Hinton, A. J.; Gunasekar, S. K.; Minerath, R. A.; Shen, K.; Maurer, J. M.; Grueter, C. E.; Abel, E. D.; Meyer, G.; Sah, R.
10.1101/2020.06.04.134213 — cell biology — Posted on 2020-06-26
838 SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes
Manley, J. L.; Lieu, Y. K.; Liu, Z.; Wei, X.; Penson, A.; Zhang, J.; An, X.; Rabadan, R.; Raza, A.; Mukherjee, S.
10.1101/2020.06.24.169052 — cancer biology — Posted on 2020-06-26
839 Computational Studies of Substrate Transport and Specificity in a Phospholipid Flippase
Wang, Y.; Lyons, J. A.; Timcenko, M.; de Groot, B. L.; Nissen, P.; Gapsys, V.; Lindorff-Larsen, K.
10.1101/2020.06.24.169771 — biophysics — Posted on 2020-06-26
840 Three LysM effectors of Zymoseptoria tritici collectively disarm chitin-triggered plant immunity
Tian, H.; McKenzie, C.; Rodriguez-Moreno, L.; van den Berg, G.; Chen, H.; Rudd, j.; Mesters, J.; Thomma, B.
10.1101/2020.06.24.169789 — plant biology — Posted on 2020-06-26
842 Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease
Audain, E.; Wilsdon, A.; Breckpot, J.; Izarzugaza, J. M.; Fitzgerald, T. W.; Anne-Karin, K.; Sifrim, A.; Wuennemann, F.; Perez-Riverol, Y.; Abdul-Khaliq, H.; Bak, M.; Bassett, A. S.; Belmont, J.; Benson, W. D.; Berger, F.; Daehnert, I.; Devriendt, K.; Dittrich, S.; Daubeney, P.; Garg, V.; Hackmann, K.; Hoff, K.; Hofmann, P.; Dombrowsky, G.; Pickardt, T.; Bauer, U.; Keavney, B.; Klaassen, S.; Kramer, H.-H.; Marshall, C. R.; Milewicz, D. M.; Lemaire, S.; Coselli, J.; Mitchell, M. E.; Tomita-Mitchell, A.; Prakash, S. K.; Stamm, K.; Stewart, A. F.; Silversides, C. K.; Siebert, R.; Stiller, B.; Ros
10.1101/2020.06.25.169573 — genetics — Posted on 2020-06-25
844 Distributions of LRS in varying environments
Tuljapurkar, S. D.; Zuo, W.; Coulson, T.; Horvitz, C.; Gaillard, J.-M.
10.1101/2020.06.24.169425 — ecology — Posted on 2020-06-25
845 A new method for counting reproductive structures in digitized herbarium specimens using Mask R-CNN
DAVIS, C. C.; Champ, J.; Park, D. S.; Breckheimer, I.; Lyra, G.; Xie, J.; Joly, A.; Tarapore, D.; Ellison, A. M.; Bonnet, P.
10.1101/2020.06.25.169888 — ecology — Posted on 2020-06-25
846 Predicting range shifts of African apes under global change scenarios
Carvalho, J.; Graham, B.; Bocksberger, G.; Maisels, F.; Williamson, E. A.; Wich, S.; Sop, T.; Amarasekaran, B.; Bergl, R. A.; Boesch, C.; Boesch, H.; Brncic, T. M.; Buys, B.; Chancellor, R.; Danquah, E.; Doumbe, O. A.; Galat-Luong, A.; Ganas, J.; Gatti, S.; Ghiurghi, A.; Goedmakers, A.; Granier, N.; Hakizimana, D.; Haurez, B.; Head, J.; Herbinger, I.; Hillers, A.; Jones, S.; Manasseh, E.-N.; McCarthy, M. S.; Morgan, B. J.; Nixon, S.; Nkembi, L.; Normand, E.; Olson, S. H.; Payne, L.; Petre, C.-A.; Piel, A. K.; Pintea, L.; Plumptre, A.; Rundus, A.; Serckx, A.; Stewart, F. A.; Sunderland-Groves,
10.1101/2020.06.25.168815 — ecology — Posted on 2020-06-25
847 Intra-session test-retest reliability of functional connectivity in infants
Wang, Y.; Hinds, W.; Duarte, C. S.; Lee, S.; Monk, C.; Wall, M.; Canino, G.; Milani, A. C. C.; Jackowski, A.; Mamin, M. G.; Foerster, B. U.; Gringrich, J.; Weissman, M. M.; Peterson, B.; Semanek, D.; Perez, E. A.; Labat, E.; Torres, I. B.; Silva, I. D.; Parente, C.; Abdala, N.; Posner, J.
10.1101/2020.06.25.169524 — bioinformatics — Posted on 2020-06-25
854 Differential role of cytosolic Hsp70s in longevity assurance and protein quality control
Andersson, R.; Eisele-Bürger, A. M.; Hanzen, S.; Vielfort, K.; Öling, D.; Eisele, F.; Johansson, G.; Gustafsson, T.; Kvint, K.; Nyström, T.
10.1101/2020.06.25.170670 — molecular biology — Posted on 2020-06-25
857 Rapid Single Cell Evaluation of Human Disease and Disorder Targets Using REVEAL: SingleCell™
Pitluk, Z. W.; Kumar, N.; Golhar, R.; Sen Sharma, K.; Sarangi, S.; Walsh, A. M.; Neuhaus, I.; Holloway, J. L.
10.1101/2020.06.24.169730 — molecular biology — Posted on 2020-06-25
858 A multi-omic integrative scheme characterizes tissues of action at loci associated with type 2 diabetes
Torres, J. M.; Abdalla, M.; Payne, A.; Fernandez-Tajes, J.; Thurner, M.; Nylander, V.; Gloyn, A. L.; Mahajan, A.; Mccarthy, M. M.
10.1101/2020.06.25.169706 — genetics — Posted on 2020-06-25
862 Increased baseline RASGRP1 signals Enhance Stem Cell Fitness during Native Hematopoiesis
Karra, L.; Romero-Moya, D.; Ksionda, O.; Krush, M.; Gu, Z.; Mues, M.; Depeille, P.; Mullighan, C.; Roose, J.
10.1101/2020.06.24.169631 — cancer biology — Posted on 2020-06-25
863 More than noise: context-dependant luminance contrast discrimination in a coral reef fish (Rhinecanthus aculeatus)
van den Berg, C.; Hollenkamp, M.; Mitchell, L. J.; Watson, E. J.; Green, N. F.; Marshall, N. J.; Cheney, K. L.
10.1101/2020.06.25.168443 — animal behavior and cognition — Posted on 2020-06-25
864 LDpred2: better, faster, stronger
Prive, F.; Arbel, J.; Vilhjalmsson, B. J.
10.1101/2020.04.28.066720 — genetics — Posted on 2020-06-25
867 ANALYSIS OF MICROBIAL DIVERSITY IN RAW FISH CEVICHE
Ramirez-Martinez, M. E.; Rodrigez-Castillejos, G. C.; Hernandez.-Jimenez, M. C.; Ramirez-Quintanilla, L. Y.; Siller-Lopez, F.; Acosta-Cruz, E.; Martinez-Montoya, H.
10.1101/2020.06.24.170217 — microbiology — Posted on 2020-06-25
869 Phototrophic co-cultures from extreme environments: community structure and potential value for fundamental and applied research
Shaw, C.; Brooke, C. G.; Connolly, M. P.; Garcia, J. A.; Harmon-Smith, M.; Shapiro, N.; Hawley, E.; Barton, M.; Tringe, S. G.; Glavina del Rio, T.; Culley, D. E.; Castenholtz, R.; Hess, M.
10.1101/427211 — microbiology — Posted on 2020-06-25
870 BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Bittner, Z. A.; Liu, X.; Shankar, S.; Tapia Abellan, A.; Kalbacher, H.; Andreeva, L.; Mangan, M.; Duewell, P.; Lovotti, M.; Bosch, K.; Dickhoefer, S.; Marcu, A.; Stevanovic, S.; Herster, F.; Loeffler, M. W.; Wolz, O. O.; Shilling, N. A.; Kuemmerle-Deschner, J.; Wagner, S.; Delor, A.; Grimbacher, B.; Wu, H.; Latz, E.; Weber, A. N.
10.1101/864702 — immunology — Posted on 2020-06-25
872 Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries
Kwong, A.; Blackwell, T. W.; LeFaive, J.; de Andrade, M.; Barnard, J.; Barnes, K. C.; Blangero, J.; Boerwinkle, E.; Burchard, E. G.; Cade, B. E.; Chasman, D.; Chen, H.; Conomos, M.; Cupples, L. A.; Ellinor, P. T.; Eng, C.; Gao, Y.; Guo, X.; Irvin, M. R.; Kelly, T.; Kim, W.; Kooperberg, C.; Lubitz, S. A.; Mak, A. C. Y.; Manichaikul, A. W.; Mathias, R. A.; Montasser, M. E.; Montgomery, C. G.; Musani, S.; Palmer, N. D.; Peloso, G.; Qiao, D.; Reiner, A. P.; Roden, D. M.; Shoemaker, M. B.; Smith, J. A.; Smith, N. L.; Lasky-Su, J. A.; Tiwari, H. K.; Weeks, D. E.; Weiss, S. T.; NHLBI Trans-Omics for
10.1101/2020.06.23.167759 — genetics — Posted on 2020-06-25
873 Targeted over-expression of PPARγ in pig skeletal muscle improves oxidative fiber formation and intramuscular fat deposition
Gu, H.; Zhou, Y.; Yang, J. Z.; Li, J. N.; Peng, Y. X.; Zhang, X.; Miao, Y. L.; Jiang, W.; Bu, G. W.; Hou, L. M.; Li, T.; Zhang, L.; Xia, X. L.; Ma, Z. Y.; Xiong, Y. Z.; Zuo, B.
10.1101/2020.06.24.168641 — genetics — Posted on 2020-06-25
875 Biodegradation of polyester polyurethane by Aspergillus flavus G10
Schaefer, D. A.; Khan, S.; Nadir, S.; Dong, Y.; Mortimer, P. E.; Gui, H.; Khan, A.; Yu, M.; Iqbal, S.; Sheng, J.; Xu, J.
10.1101/2020.06.25.170654 — bioengineering — Posted on 2020-06-25
878 In vitro activity evaluation of Lippia alba essential oil against Zika virus
Quispe-Bravo, B. E.; Sevilla Drozdek, L. A.; Hermosilla Jara, J.; Collantes Diaz, I. E.; Luiz Durigon, E.; Mamani Zapana, E. W.; Mayta Huatuco, E. M.; Sulca Herencia, J. S.
10.1101/2020.06.25.170720 — pharmacology and toxicology — Posted on 2020-06-25
879 Longitudinal ComBat: A Method for Harmonizing Longitudinal Multi-scanner Imaging Data
Beer, J. C.; Tustison, N. J.; Cook, P. A.; Davatzikos, C.; Sheline, Y. I.; Shinohara, R. T.; Linn, K. A.
10.1101/868810 — neuroscience — Posted on 2020-06-25
880 Altered central pain processing in fibromyalgia - a multimodal neuroimaging case-control study using arterial spin labelling
Müller, M.; Wüthrich, F.; Federspiel, A.; Wiest, R.; Egloff, N.; Reichenbach, S.; Exadaktylos, A.; Jüni, P.; Curatolo, M.; Walther, S.
10.1101/2020.06.25.170647 — neuroscience — Posted on 2020-06-25
882 Application of a Novel Machine Learning Method to Big Data Infers a Relationship Between Asthma and the Development of Neoplasia
Shojaee, A.; Gomez Villalobos, J.; Wang, X.; Kaminski, N.; Siner, J.; takyar, s.; Zhao, H.; Chupp, G.
10.1101/439117 — epidemiology — Posted on 2020-06-25
887 Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes
Henley, M. J.; Linhares, B. M.; Morgan, B. S.; Fierke, C. A.; Cierpicki, T.; Mapp, A.
10.1101/2020.05.29.124271 — biochemistry — Posted on 2020-06-25
888 Constraints on the Efficiency of Electromicrobial Production
Salimijazi, F.; Kim, J.; Schmitz, A. M.; Grenville, R.; Bocarsly, A. B.; Barstow, B.
10.1101/2020.06.23.167288 — synthetic biology — Posted on 2020-06-25
892 Establishment of an in vitro culture system to study the developmental biology (growth, mating and nodule formation) of Onchocerca volvulus with implications for anti-onchocerca drug discovery and screening
Gandjui, N. V. T.; Njouendou, A. J.; Gemeg, E. N.; Fombad, F. F.; Ritter, M.; Kien, C. A.; Chunda, V. C.; Fru, J.; Esum, M. E.; Hubner, M. P.; Enyong, P. A.; Hoerauf, A.; Wanji, S.
10.1101/2020.06.25.170746 — developmental biology — Posted on 2020-06-25
901 Ultra-compact Dual-band Smart NEMS Magnetoelectric Antennas for Simultaneous Wireless Energy Harvesting and Magnetic Field Sensing
Zaeimbashi, M.; Nasrollahpour, M.; Khalifa, A.; Romano, A.; Liang, X.; Chen, H.; Sun, N.; Matyushov, A.; Lin, H.; Dong, C.; Xu, Z.; Mittal, A.; Martos-Repath, I.; Jha, G.; Mirchandani, N.; Das, D.; Onabajo, M.; Shrivastava, A.; Cash, S.; Sun, N.
10.1101/2020.06.22.165894 — bioengineering — Posted on 2020-06-25
902 Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer
Golovinas, E.; Rutkauskas, D.; Manakova, E.; Jankunec, M.; Silanskas, A.; Sasnauskas, G.; Zaremba, M.
10.1101/2020.05.06.080267 — biochemistry — Posted on 2020-06-25
904 Simple cloning of large natural product biosynthetic gene cluster by CRISPR/Cas12a-mediated fast direct capturing strategy
Liang, M.; Liu, L.; Wang, W.; Zeng, X.; Liu, J.; Loganathan, K.; Zhu, G.; Bai, L.; Hou, C.; Chen, X.; Ouyang, L.; Liu, X.; Hu, B.; Xia, X.; Tong, Y.; Lou, C.; Alterovitz, G.; Tan, G.-Y.; Zhang, L.-X.
10.1101/2020.06.25.170191 — synthetic biology — Posted on 2020-06-25
907 In vivo fluorescence imaging with a flat, lensless microscope
Adams, J. K.; Boominathan, V.; Gao, S.; Rodriguez, A. V.; Yan, D.; Kemere, C.; Veeraraghavan, A.; Robinson, J. T.
10.1101/2020.06.04.135236 — neuroscience — Posted on 2020-06-25
908 A molecular pore spans the double membrane of the coronavirus replication organelle
Wolff, G.; Limpens, R. W. A. L.; Zevenhoven-Dobbe, J. C.; Laugks, U.; Zheng, S.; de Jong, A. W. M.; Koning, R. I.; Agard, D. A.; Grünewald, K.; Koster, A. J.; Snijder, E. J.; Barcena, M.
10.1101/2020.06.25.171686 — microbiology — Posted on 2020-06-25
909 Schistosoma haematobium extracellular vesicle proteins confer protection in a heterologous model of schistosomiasis
Mekonnen, G. G.; Tedla, B. A.; Pickering, D.; Becker, L.; Wang, L.; Zhan, B.; Bottazzi, M. E.; Loukas, A.; Sotillo, J.; Pearson, M. S.
10.1101/2020.06.24.168773 — microbiology — Posted on 2020-06-25
912 Optimization of cerebrospinal fluid microbial metagenomic sequencing diagnostics
Olausson, J.; Brunet, S.; Vracar, D.; Tian, Y.; Abrahamsson, S.; Meghadri, S. H.; Sikora, P.; Lind Karlberg, M.; Engstrom Jakobsson, H.; Tang, K.-W.
10.1101/2020.06.25.170423 — microbiology — Posted on 2020-06-25
913 Evaluating aerosol and splatter following dental procedures
Allison, J.; Currie, C.; Edwards, D.; Bowes, C.; Coulter, J.; Pickering, K.; Kozhevnikova, E.; Durham, J.; Nile, C.; Jakubovics, N.; Rostami, N.; Holliday, R.
10.1101/2020.06.25.154401 — microbiology — Posted on 2020-06-25
914 Intestinal transkingdom analysis on the impact of antibiotic perturbation in health and critical illness
Haak, B. W.; Argelaguet, R.; Kinsella, C. M.; Kullberg, R. F.; Lankelma, J. M.; Hakvoort, T. B.; Hugenholtz, F.; Kostidis, S.; Giera, M.; de Jonge, W. J.; Schultz, M. J.; van Gool, T.; van der Poll, T.; de Vos, W. M.; van den Hoek, L.; Wiersinga, W. J.
10.1101/2020.06.25.171553 — microbiology — Posted on 2020-06-25
915 Evolutionary dynamics of bipartite begomoviruses revealed by complete genome analysis
Xavier, C. A.; Godinho, M. T.; Mar, T. B.; Ferro, C. G.; Sande, O. F.; Silva, J. C.; Ramos-Sobrinho, R.; Nascimento, R. N.; Assuncao, I.; Lima, G. S.; Lima, A. T.; Zerbini, F. M.
10.1101/2020.06.25.171728 — microbiology — Posted on 2020-06-25
917 Functional Annotation of Human Long Non-Coding RNAs via Molecular Phenotyping
Ramilowski, J. A.; Yip, C. W.; Agrawal, S.; Chang, J.-C.; Ciani, Y.; Kulakovskiy, I. V.; Mendez, M.; Ooi, J. L. C.; Petri, A.; Roos, L.; Severin, J.; Yasuzawa, K.; Ouyang, J. F.; Parkinson, N.; Abugessaisa, I.; Akalin, A.; Antonov, I.; Arner, E.; Bonetti, A.; Bono, H.; Borsari, B.; Brombacher, F.; Cannistraci, C.; CAMERON, C. J.; Cardenas, R.; Cardon, M.; Chang, H.; Dostie, J.; Ducoli, L.; Favorov, A.; Fort, A.; Garrido, D.; Gil, N.; Gimenez, J.; Guler, R.; Handoko, L.; Harshbarger, J.; Hasegawa, A.; Hasegawa, Y.; Hashimoto, K.; Hayatsu, N.; Heutink, P.; Hirose, T.; Imada, E. L.; Itoh, M.; Kac
10.1101/700864 — genomics — Posted on 2020-06-25
918 A catalog of homoplasmic and heteroplasmic mitochondrial DNA variants in humansed individuals
Bolze, A.; Mendez, F.; White, S.; Tanudjaja, F.; Isaksson, M.; Jiang, R.; Dei Rossi, A.; Cirulli, E. T.; Rashkin, M.; Metcalf, W. J.; Grzymski, J. J.; Lee, W.; Lu, J.; Washington, N. L.
10.1101/798264 — genetics — Posted on 2020-06-25
922 Measuring both microbial load and diversity with a single amplicon sequencing library
Lundberg, D. S.; Pramoj Na Ayutthaya, P.; Strauss, A.; Shirsekar, G.; Lo, W.-S.; Lahaye, T.; Weigel, D.
10.1101/2020.05.19.103937 — bioengineering — Posted on 2020-06-25
923 Evaluation of ExoU inhibitors in a Pseudomonas aeruginosa scratch infection assay
Foulkes, D. M.; McLean, K.; Harris, J.; Haneef, A.; Fernig, D.; Winstanley, C.; Berry, N.; Kaye, S. B.
10.1101/2020.06.24.170373 — biochemistry — Posted on 2020-06-25
924 The gut mycobiome of healthy mice is shaped by the environment and shapes metabolic outcomes in response to diet
Mims, T. S.; Al Abdullah, Q.; Stewart, J. D.; Watts, S. P.; White, C. T.; Rousselle, T. V.; Bajwa, A.; Han, J. C.; Willis, K. A.; Pierre, J. F.
10.1101/2020.06.25.158287 — microbiology — Posted on 2020-06-25
925 Positive interactions are common among culturable bacteria
Kehe, J.; Ortiz, A.; Kulesa, A.; Gore, J.; Blainey, P.; Friedman, J.
10.1101/2020.06.24.169474 — ecology — Posted on 2020-06-25
926 Comparison of 12 molecular detection assays for SARS-CoV-2
Matsumura, Y.; Shimizu, T.; Noguchi, T.; Nakano, S.; Yamamoto, M.; Nagao, M.
10.1101/2020.06.24.170332 — microbiology — Posted on 2020-06-25
927 Antiviral Drug Screen of Kinase inhibitors Identifies Cellular Signaling Pathways Critical for SARS-CoV-2 Replication
Garcia, G.; Sharma, A.; Ramaiah, A.; Sen, C.; Kohn, D.; Gomperts, B.; Svendsen, C. N.; Damoiseaux, R. D.; Arumugaswami, V.
10.1101/2020.06.24.150326 — microbiology — Posted on 2020-06-25
928 Chasing the origin of SARS-CoV-2 in Canada's COVID-19 cases: A genomics study
Sjaarda, C. P.; Rustom, N.; Huang, D.; Perez-Patrigeon, S.; Hudson, M. L.; Wong, H.; Guan, T. H.; Ayub, M.; Soares, C. N.; Colautti, R. I.; Evans, G. A.; Sheth, P. M.
10.1101/2020.06.25.171744 — microbiology — Posted on 2020-06-25
933 Interplay of BAF and MLL4 promotes cell type-specific enhancer activation
Park, Y.-K.; Lee, J.-E.; OHaren, T.; McKernan, K.; Yan, Z.; Wang, W.; Peng, W.; Ge, K.
10.1101/2020.06.24.168146 — molecular biology — Posted on 2020-06-25
934 Immune fingerprinting
Dupic, T.; Bensouda Koraichi, M.; Minervina, A.; Pogorelyy, M.; Mora, T.; Walczak, A. M.
10.1101/2020.06.24.168484 — genetics — Posted on 2020-06-25
935 Modeling the effect of COVID-19 disease on the cardiac function: a computational study
Regazzoni, F.; Vergara, C.; Dede', L.; Zunino, P.; Guglielmo, M.; Scrofani, R.; Fusini, L.; Cogliati, C.; Pontone, G.; Quarteroni, A.
10.1101/2020.06.23.166421 — pathology — Posted on 2020-06-25
938 Ionophore antibiotic X-206 is a potent and selective inhibitor of SARS-CoV-2 infection in vitro
Svenningsen, E. B.; Jensen, J. T.; Blay-Cadanet, J.; Liu, H.; Lin, S.; Villameriel, J. M.; Olagnier, D.; Idorn, M.; Paludan, S. R.; Holm, C. K.; Poulsen, T. B.
10.1101/2020.06.14.149153 — pharmacology and toxicology — Posted on 2020-06-25
940 CoV3D: A database and resource for high resolution coronavirus protein structures
Gowthaman, R.; Guest, J. D.; Yin, R.; Adolf-Bryfogle, J.; Schief, W. R.; Pierce, B. G.
10.1101/2020.05.12.091983 — microbiology — Posted on 2020-06-25
941 Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs
Kern, D. M.; Sorum, B.; Hoel, C. M.; Sridharan, S.; Remis, J. P.; Toso, D. B.; Brohawn, S. G.
10.1101/2020.06.17.156554 — biophysics — Posted on 2020-06-25
942 Predicting wildlife hosts of betacoronaviruses for SARS-CoV-2 sampling prioritization
Becker, D.; Albery, G. F.; Sjodin, A. R.; Poisot, T.; Dallas, T.; Eskew, E. A.; Farrell, M. J.; Guth, S.; Han, B. A.; Simmons, N. B.; Stock, M.; Teeling, E. C.; Carlson, C. J.
10.1101/2020.05.22.111344 — ecology — Posted on 2020-06-25
945 Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set
Kebschull, J. M.; Ringach, N.; Richman, E. B.; Friedmann, D.; Kolluru, S. S.; Jones, R. C.; Allen, W. E.; Wang, Y.; Zhou, H.; Cho, S. W.; Chang, H.; Deisseroth, K.; Quake, S. R.; Luo, L.
10.1101/2020.06.25.170118 — neuroscience — Posted on 2020-06-25
946 Dissociation between catecholamines and acetylcholine in the human cerebral cortex
Pfeffer, T.; Ponce-Alvarez, A.; Meindertsma, T.; Gahnstrom, C.; van den Brink, R. L.; Nolte, G.; Tsetsos, K.; Engel, A. K.; Deco, G.; Donner, T. H.
10.1101/2020.06.25.171199 — neuroscience — Posted on 2020-06-25
949 Organization and control of the ascorbate biosynthesis pathway in plants
Fenech, M.; Amorim-Silva, V.; Esteban del Valle, A.; Arnaud, D.; Castillo, A. G.; Smirnoff, N.; Botella, M. A.
10.1101/2020.06.23.167247 — molecular biology — Posted on 2020-06-25
951 The SERCA residue Glu340 mediates inter-domain communication that guides Ca2+ transport
Clausen, J. D.; Arnou, B.; Geurts, M. M. G.; Montigny, C.; Lenoir, G.; Corey, R. A.; Jaxel, C.; Moeller, J.; Nissen, P.; Andersen, J. P.; le Maire, M.; Bublitz, M.
10.1101/2020.06.22.165365 — molecular biology — Posted on 2020-06-25
953 Variability of dynamic patterns of cortical excitability in schizophrenia: A test-retest TMS-EEG study
Naim-Feil, J.; Peled, A.; Freche, D.; Hess, S.; Grinshpoon, A.; Levit-Binnun, N.; Moses, E.
10.1101/2020.06.24.170019 — neuroscience — Posted on 2020-06-25
954 Deciphering the regulatory logic of a Drosophila enhancer through systematic sequence mutagenesis and quantitative image analysis
Le Poul, Y.; Xin, Y.; Ling, L.; Mühling, B.; Jaenichen, R.; Hörl, D.; Bunk, D.; Harz, H.; Leonhardt, H.; Wang, Y.; Osipova, E.; Museridze, M.; Dharmadhikari, D.; Murphy, E.; Rohs, R.; Preibisch, S.; Prud'homme, B.; Gompel, N.
10.1101/2020.06.24.169748 — genetics — Posted on 2020-06-25
955 Structural basis of Blastomyces Endoglucanase-2adjuvancy in anti-fungal and -viral immunity
Dos Santos Dias, L.; Dobson, H. E.; Kingstad Bakke, B.; Kujoth, G. C.; Huang, J.; Kohn, E. M.; Ledesma Taira, C.; Wang, H.; Supekar, N. T.; Azadi, P.; Li, l.; Suresh, M.; klein, b. s.; Wuethrich, M.
10.1101/2020.06.24.169763 — immunology — Posted on 2020-06-25
957 Striatal dopamine supports reward reactivity and learning: A simultaneous PET/fMRI study
Calabro, F. J.; Montez, D.; Larsen, B.; Laymon, C.; Foran, W.; Hallquist, M.; Price, J.; Luna, B.
10.1101/2020.06.24.169722 — neuroscience — Posted on 2020-06-24
958 Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues
Liu, C. M.; Hsu, T. M.; Suarez, A. N.; Subramanian, K. S.; Fatemi, R. A.; Cortella, A. M.; Noble, E. E.; Roitman, M. F.; Kanoski, S. E.
10.1101/2020.06.24.169540 — neuroscience — Posted on 2020-06-24
961 Lentiviral interleukin-10 gene therapy preserves fine motor circuitry and function after a cervical spinal cord injury in male and female mice
Chen, J. Y.; Fu, E. J.; Patel, P. R.; Sawan, H. A.; Moss, K. A.; Hostetler, A. J.; Hocevar, S. E.; Anderson, A. J.; Chestek, C. A.; Shea, L. D.
10.1101/2020.06.05.137257 — neuroscience — Posted on 2020-06-25
970 Cell cycle checkpoints cooperate to suppress DNA and RNA associated molecular pattern recognition and anti-tumor immune responses
Greenberg, R. A.; Chen, J.; Harding, S. M.; Ramakrishnan, N.; Tian, L.; Benci, J.; Li, W.; Minn, A. J.; Asangani, I.
10.1101/2020.06.24.168971 — cell biology — Posted on 2020-06-24
972 Puromycin reactivity does not accurately localize translation at the subcellular level
Enam, S. U.; Zinshteyn, B.; Goldman, D. H.; Cassani, M.; Livingston, N. M.; Seydoux, G.; Green, R.
10.1101/2020.06.22.165217 — biochemistry — Posted on 2020-06-24
978 Dopa decarboxylase is a genetic hub of parental control over offspring behavior
Bonthuis, P. J.; Steinwand, S.; Huang, W.-C.; Horndli, C. N. S.; Emery, J.; Kravitz, S.; Ferris, E.; Gregg, C.
10.1101/2020.06.23.168195 — neuroscience — Posted on 2020-06-24
982 Systems genetics analyses in Diversity Outbred mice inform human bone mineral density GWAS and identify Qsox1 as a novel determinant of bone strength
Al-Barghouthi, B. M.; Mesner, L. M.; Calabrese, G. M.; Brooks, D. J.; Tommasini, S. M.; Bouxsein, M. L.; Horowitz, M. C.; Rosen, C. J.; Nguyen, K.; Haddox, S.; Farber, E. A.; Onengut-Gumuscu, S.; Pomp, D.; Farber, C.
10.1101/2020.06.24.169839 — genetics — Posted on 2020-06-24
984 Ultra-rapid metagenotyping of the human gut microbiome
Shi, Z. J.; Dimitrov, B.; Zhao, C.; Nayfach, S.; Pollard, K. S.
10.1101/2020.06.12.149336 — bioinformatics — Posted on 2020-06-24
986 Fast oscillations >40Hz localize the epileptogenic zone: an electrical source imaging study using high-density electroencephalography
Avigdor, T.; Abdallah, C.; von Ellenrieder, N.; Rubino, A.; Lo Russo, G.; Hedrich, T.; Bernhardt, B.; Nobili, L.; Grova, C.; Frauscher, B.
10.1101/2020.03.02.973602 — neuroscience — Posted on 2020-06-24
987 Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage
Guth-Metzler, R.; Bray, M. S.; Frenkel-Pinter, M.; Suttapitugsakul, S.; Montllor-Albalate, C.; Bowman, J. C.; Wu, R.; Reddi, A. R.; Okafor, C. D.; Glass, J. B.; Williams, L. D.
10.1101/851097 — molecular biology — Posted on 2020-06-24
988 Intestinal receptor of SARS-CoV-2 in inflamed IBD tissue is downregulated by HNF4A in ileum and upregulated by interferon regulating factors in colon
Verstockt, B.; Verstockt, S.; Adbu Rahiman, S.; Ke, B.-J.; Arnauts, K.; Cleynen, I.; Sabino, J.; Ferrante, M.; Matteoli, G.; Vermeire, S.
10.1101/2020.06.24.169383 — genomics — Posted on 2020-06-24
989 JAGGED1 Stimulates Cranial Neural Crest Cell Osteoblast Commitment Pathways and Bone Regeneration Independent of Canonical NOTCH Signaling
Kamalakar, A.; McKinney, J. M.; Salinas Duron, D.; Amanso, A. M.; Ballestas-Naissir, S. A.; Drissi, H.; Willett, N. J.; Bhattaram, P.; Garcia, A. J.; Wood, L. B.; Goudy, s.
10.1101/2020.06.24.169755 — genomics — Posted on 2020-06-24
990 Formicine ants swallow their highly acidic poison for gut microbial selection and control
Tragust, S.; Herrmann, C.; Häfner, J.; Braasch, R.; Tilgen, C.; Hoock, M.; Milidakis, M. A.; Gross, R.; Feldhaar, H.
10.1101/2020.02.13.947432 — evolutionary biology — Posted on 2020-06-24
991 The CRISPR-Cas9 crGART HeLa transcriptome: A novel cell model of de novo purine synthesis deficiency
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.06.23.167924 — cell biology — Posted on 2020-06-24
996 Noise-induced scaling in skull suture interdigitation
Naroda, Y.; Endo, Y.; Yoshimura, K.; Ishii, H.; Ei, S.-I.; Miura, T.
10.1101/2020.06.24.168674 — developmental biology — Posted on 2020-06-24
999 Disease-relevant single cell photonic signatures identify S100β stem cells and their myogenic progeny in vascular lesions
Molony, C.; King, D.; di Luca, M.; Olayinka, A.; Hakimjavadi, R.; Julius, L. A.; Fitzpatrick, E.; Gusti, Y.; Burtenshaw, D.; Healy, K.; Finlay, E.; Kernan, D.; Llobera, A.; Liu, W.; Morrow, D.; Redmond, E. M.; Ducree, J.; Cahill, P. A.
10.1101/2020.05.13.093518 — cell biology — Posted on 2020-06-24
1000 Expression and Pharmacological Inhibition of TrkB and EGFR in Glioblastoma
Pinheiro, K. d. V.; Thomaz, A.; Souza, B. K.; Metcalfe, V. A.; Freire, N. H.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M.; Bambini, V.; Smith, C. G. S.; Shaw, L.; Roesler, R.
10.1101/2020.02.03.932608 — cancer biology — Posted on 2020-06-24
1003 Parvalbumin+ and Npas1+ Pallidal Neurons Have Distinct Circuit Topology and Function
Pamukcu, A.; Cui, Q.; Xenias, H.; Berceau, B.; Augustine, E.; Fan, I.; Chalasani, S.; Hantman, A.; Lerner, T.; Boca, S.; Chan, S.
10.1101/2020.02.14.950006 — neuroscience — Posted on 2020-06-24
1004 Removal of Scanner Effects in Covariance Improves Multivariate Pattern Analysis in Neuroimaging Data
Chen, A. A.; Beer, J. C.; Tustison, N. J.; Cook, P. A.; Shinohara, R. T.; Shou, H.
10.1101/858415 — neuroscience — Posted on 2020-06-24
1007 Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR
Park, C.; Peng, C.; Rahman, M. J.; Haller, S. L.; Tazi, L.; Brennan, G. J.; Rothenburg, S.
10.1101/2020.02.20.958645 — microbiology — Posted on 2020-06-24
1010 Ultra-deep sequencing differentiates patterns of skin clonogenic mutations associated with sun-exposure status and skin cancer risk
Wei, L.; Christensen, S.; Fitzgerald, M.; Graham, J.; Hutson, N.; Zhang, C.; Huang, Z.; Hu, Q.; Zhan, F.; Xie, J.; Zhang, J.; Liu, S.; Remenyik, E.; Gellen, E.; Colegio, O. R.; Bax, M.; Xu, J.; Lin, H.; Huss, W. J.; Foster, B. A.; Paragh, G.
10.1101/2020.01.10.902098 — cancer biology — Posted on 2020-06-24
1013 Diffusion MRI free water is a sensitive marker of age-related changes in the cingulum
Edde, M.; Theaud, G.; Rheault, F.; Dilharreguy, B.; Helmer, C.; Dartigues, J.-F.; Amieva, H.; Allard, M.; Descoteaux, M.; Catheline, G.
10.1101/867606 — neuroscience — Posted on 2020-06-24
1017 Pixatimod (PG545), a clinical-stage heparan sulfate mimetic, is a potent inhibitor of the SARS-CoV-2 virus
Guimond, S. E.; Mycroft-West, C. J.; Gandhi, N. S.; Tree, J. A.; Buttigieg, K. R.; Coombes, N.; Nystrom, K.; Said, J.; Setoh, Y. X.; Amarilla, A.; Modhiran, N.; Sng, D. J. J.; Chhabra, M.; Watterson, D.; Young, P. R.; Khromykh, A. A.; Lima, M. A.; Fernig, D. G.; Su, D.; Yates, E. A.; Hammond, E.; Dredge, K.; Carroll, M. W.; Trybala, E.; Bergstrom, T.; Ferro, V.; Skidmore, M. A.; Turnbull, J. E.
10.1101/2020.06.24.169334 — microbiology — Posted on 2020-06-24
1019 CoronaHiT: large scale multiplexing of SARS-CoV-2 genomes using Nanopore sequencing
Baker, D. J.; Kay, G. L.; Aydin, A.; Le-Viet, T.; Rudder, S.; Tedim, A. P.; Kolyva, A.; Diaz, M.; Martins, L. d. O.; Alikhan, N.-F.; Meadows, L.; Bell, A.; Gutierrez, A. V.; Trotter, A. J.; Thomson, N. M.; Gilroy, R.; Griffith, L.; Adriaenssens, E. M.; Stanley, R.; Charles, I. G.; Elumogo, N.; Wain, J.; Prakash, R.; Meader, E.; Mather, A. E.; Webber, M. A.; Dervisevic, S.; Page, A. J.; O'Grady, J.
10.1101/2020.06.24.162156 — genomics — Posted on 2020-06-24
1020 Transcriptional differences between the two host strains of Spodoptera frugiperda (Lepidoptera: Noctuidae)
Orsucci, M.; Mone, Y.; Audiot, P.; Gimenez, S.; Nhim, S.; Nait-Saidi, R.; Frayssinet, M.; Dumont, G.; Boudon, J.-P.; Vabre, M.; Rialle, S.; Koual, R.; Kergoat, G. J.; Nagoshi, R. N.; Meagher, R. L.; d'Alencon, E.; Negre, N.
10.1101/263186 — evolutionary biology — Posted on 2020-06-24
1021 Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network.
Hutchings, J.; Stancheva, V. G.; Brown, N. R.; Cheung, A. M.; Miller, E. A.; Zanetti, G.
10.1101/2020.06.18.159608 — cell biology — Posted on 2020-06-24
1022 Gene Regulatory Network Inference as Relaxed Graph Matching
Weighill, D.; Guebila, M. B.; Lopes-Ramos, C.; Glass, K.; Quackenbush, J.; Platig, J.; Burkholz, R.
10.1101/2020.06.23.167999 — bioinformatics — Posted on 2020-06-24
1023 From Value to Saliency: Neural Computations of Subjective Value under Uncertainty in Combat Veterans
Jia, R.; Ruderman, L.; Gordon, C.; Ehrlich, D.; Horvath, M.; Mirchandani, S.; DeFontes, C.; Southwick, S.; Krystal, J. H.; Harpaz-Rotem, I.; Levy, I.
10.1101/2020.04.14.041467 — neuroscience — Posted on 2020-06-24
1026 Learning cognitive maps for vicarious evaluation
Rikhye, R. V.; Gothoskar, N.; Guntupalli, J. S.; Dedieu, A.; Lazaro-Gredilla, M.; George, D.
10.1101/864421 — neuroscience — Posted on 2020-06-24
1027 Deforestation and bird habitat loss in Colombia
Negret, P. J.; Maron, M.; Fuller, R.; Possingham, H.; Watson, J.; Simmonds, J.
10.1101/2020.05.30.125849 — ecology — Posted on 2020-06-24
1028 WNK1 regulates uterine homeostasis and its ability to support pregnancy
Chi, R.-p. A.; Wang, T.; Huang, C.-l.; Wu, S.-P.; Young, S. L.; Lydon, J. P.; DeMayo, F. J.
10.1101/2020.03.27.012039 — developmental biology — Posted on 2020-06-24
1029 SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids
Giobbe, G. G.; Bonfante, F.; Zambaiti, E.; Gagliano, O.; Jones, B. C.; Luni, C.; Laterza, C.; Perin, S.; Stuart, H. T.; Pagliari, M.; Bortolami, A.; Mazzetto, E.; Manfredi, A.; Colantuono, C.; Di Filippo, L.; Pellegata, A. F.; Li, V. S. W.; Eaton, S.; Thapar, N.; Cacchiarelli, D.; Elvassore, N.; De Coppi, P.
10.1101/2020.06.24.167049 — cell biology — Posted on 2020-06-24
1030 Modular genetic control of social status in a cichlid fish
Alward, B. A.; Laud, V.; Skalnik, C. J.; York, R. A.; Juntti, S. A.; Fernald, R. D.
10.1101/2020.04.03.024190 — animal behavior and cognition — Posted on 2020-06-24
1038 Targeted over-expression of PPARγ in pig skeletal muscle improves oxidative fiber formation and intramuscular fat deposition
Gu, H.; Zhou, Y.; Yang, J. Z.; Li, J. N.; Peng, Y. X.; Zhang, X.; Miao, Y. L.; Jiang, W.; Bu, G. W.; Hou, L. M.; Li, T.; Zhang, L.; Xia, X. L.; Ma, Z. Y.; Xiong, Y. Z.; Zuo, B.
10.1101/2020.06.24.168641 — genetics — Posted on 2020-06-24
1040 Shared and unique brain network features predict cognition, personality and mental health in childhood
Chen, J.; Tam, A.; Kebets, V.; Orban, C.; Ooi, L. Q. R.; Marek, S.; Dosenbach, N.; Eickhoff, S.; Bzdok, D.; Holmes, A. J.; Yeo, B. T. T.
10.1101/2020.06.24.168724 — neuroscience — Posted on 2020-06-24
1046 Enhanced anti-amyloid effect of combined leptin and pioglitazone in APP/PS1 transgenic mice
Liu, Y.; Hanson, K. A.; McCormack, G.; Dittmann, J.; Vickers, J. C.; Fernandez-Martos, C. M.; King, A. E.
10.1101/2020.06.24.168518 — neuroscience — Posted on 2020-06-24
1050 In situ classification of cell types in human kidney tissue using 3D nuclear staining
Woloshuk, A.; Khochare, S.; Almulhim, A. F.; McNutt, A.; Dean, D.; Barwinska, D.; Ferkowicz, M.; Eadon, M. T.; Kelly, K. J.; Dunn, K. W.; Hasan, M. A.; El-Achkar, T. M.; Winfree, S.
10.1101/2020.06.24.167726 — cell biology — Posted on 2020-06-24
1055 Systems genetic analysis of binge-like eating in a C57BL/6J x DBA/2J-F2 cross
Yao, E. J.; Babbs, R. K.; Kelliher, J. C.; Luttik, K. P.; Damaj, M. I.; Mulligan, M. K.; Bryant, C. D.
10.1101/2020.06.24.168930 — genetics — Posted on 2020-06-24
1056 Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives
Wind, M.; Gogolou, A.; Manipur, I.; Granata, I.; Butler, L.; Andrews, P. W.; Barbaric, I.; Ning, K.; Guarracino, M. R.; Placzek, M.; Tsakiridis, A.
10.1101/2020.06.24.168625 — developmental biology — Posted on 2020-06-24
1058 Thermodynamic analysis of point mutations inhibiting high-temperature reversible oligomer of PDZ3
Saotome, T.; Mezaki, T.; Subbaian, B.; Unzai, S.; Martinez, J. C.; Kidokoro, S.-i.; Kuroda, Y.
10.1101/2020.06.24.169607 — biophysics — Posted on 2020-06-24
1061 Genomes of Thaumarchaeota from deep sea sediments reveal specific adaptations of three independently evolved lineages
Kerou, M.; Ponce-Toledo, R. I.; Zhao, R.; Abby, S. S.; Hirai, M.; Nomaki, H.; Takaki, Y.; Nunoura, T.; Jorgensen, S. L.; Schleper, C.
10.1101/2020.06.24.168906 — microbiology — Posted on 2020-06-24
1062 Strengthening The Organizing and Reporting of Microbiome Studies (STORMS)
Mirzayi, C. A.; Renson, A.; Zohra, F.; Elsafoury, S.; Kasselman, L.; van de Wijgert, J. H.; Segata, N.; Beghini, F.; Eckenrode, K.; Dowd, J. B.; Jones, H.; Waldron, L. D.
10.1101/2020.06.24.167353 — genomics — Posted on 2020-06-24
1063 Heterogeneity of murine periosteum osteochondroprogenitors involved in fracture healing
Matthews, B. G.; Sbrana, F. V.; Novak, S.; Funnell, J. L.; Cao, Y.; Buckels, E. J.; Grcevic, D.; Kalajzic, I.
10.1101/2020.06.24.169003 — developmental biology — Posted on 2020-06-24
1064 DNA origami demonstrate the unique stimulatory power of single pMHCs as T-cell antigens
Hellmeier, J.; Platzer, R.; Eklund, A. S.; Schlichthaerle, T.; Karner, A.; Motsch, V.; Kurz, E.; Bamieh, V.; Brameshuber, M.; Preiner, J.; Jungmann, R.; Stockinger, H.; Schuetz, G. J.; Huppa, J. B.; Sevcsik, E.
10.1101/2020.06.24.166850 — biophysics — Posted on 2020-06-24
1066 AN ADMIXTURE SIGNAL IN ARMENIANS AROUND THE END OF THE BRONZE AGE REVEALS WIDESPREAD POPULATION MOVEMENT ACROSS THE MIDDLE EAST
Hovhannisyan, A.; Jones, E.; Maisano Delser, P.; Schraiber, J.; Hakobyan, A.; Margaryan, A.; Hrechdakian, P.; Sahakyan, H.; Saag, L.; Khachatryan, Z.; Yepiskoposyan, L.; Manica, A.
10.1101/2020.06.24.168781 — genomics — Posted on 2020-06-24
1069 DREIMT: a drug repositioning database and prioritization tool for immunomodulation.
Troule, K.; Lopez-Fernandez, H.; Garcia-Martin, S.; Reboiro-Jato, M.; Carretero-Puche, C.; Martorell-Marugan, J.; Martin-Serrano, G.; Carmona-Saez, P.; Gonzalez-Pena, D.; Al-Shahrour, F.; Gomez-Lopez, G.
10.1101/2020.06.24.168468 — bioinformatics — Posted on 2020-06-24
1070 Mutalyzer 2: Next Generation HGVS Nomenclature Checker
Lefter, M.; Vis, J. K.; Vermaat, M.; den Dunnen, J. T.; Taschner, P. E. M.; Laros, J. F. J.
10.1101/2020.06.24.168583 — bioinformatics — Posted on 2020-06-24
1071 Stressful times in a climate crisis: how will aphids respond to more frequent drought?
Leybourne, D. J.; Preedy, K. F.; Valentine, T. A.; Bos, J. I.; Karley, A. J.
10.1101/2020.06.24.168112 — ecology — Posted on 2020-06-24
1073 Structures of the Cmr-βComplex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas
Sofos, N.; Feng, M.; Stella, S.; Pape, T.; Fuglsgang, A.; Lin, J.; Huang, Q.; Li, Y.; She, Q.; Montoya, G.
10.1101/2020.06.24.163345 — biochemistry — Posted on 2020-06-24
1075 Elucidation of regulatory modes for five two-component systems in Escherichia coli reveals novel relationships
Choudhary, K. S.; Kleinmanns, J. A.; Decker, K.; Sastry, A. V.; Gao, Y.; Szubin, R.; Seif, Y.; Palsson, B. O.
10.1101/2020.06.23.168344 — systems biology — Posted on 2020-06-24
1081 Structural basis for no spectral shift of heliorhodopsin by counterion mutation
Tanaka, T.; Singh, M.; Shihoya, W.; Yamashita, K.; Kandori, H.; Nureki, O.
10.1101/2020.06.24.168591 — biochemistry — Posted on 2020-06-24
1084 The native structure of the full-length, assembled influenza A virus matrix protein, M1.
Peukes, J.; Xiong, X.; Erlendsson, S.; Qu, K.; Wan, W.; Calder, L. J.; Schraidt, O.; Kummer, S.; Freund, S. M. V.; Kräusslich, H.-G.; Briggs, J. A. G.
10.1101/2020.06.24.168567 — biochemistry — Posted on 2020-06-24
1085 Daptomycin resistance in Enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway
Prater, A. G.; Mehta, H. H.; Beabout, K.; Supandy, A.; Miller, W. R.; Tran, T. T.; Arias, C. A.; Shamoo, Y.
10.1101/2020.06.23.168401 — microbiology — Posted on 2020-06-24
1086 Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes
Vysotskiy, M.; Zhong, X.; Miller-Fleming, T. W.; Zhou, D.; Autism Working Group of the Psychiatric Genomics Consortium, ; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Schizophrenia Working Group of the Psychiatric Genomics Consortium, ; Cox, N. J.; Weiss, L. A.
10.1101/2020.06.23.166181 — genetics — Posted on 2020-06-24
1087 Phylogeographic structure of the dunes sagebrush lizard, an endemic habitat specialist
Chan, L. M.; Painter, C. W.; Hill, M. T.; Hibbitts, T. J.; Leavitt, D. J.; Ryberg, W. A.; Walkup, D.; Fitzgerald, L. A.
10.1101/2020.06.23.168088 — evolutionary biology — Posted on 2020-06-24
1089 Rewiring the specificity of extra-cytoplasmic function sigma factors
Todor, H.; Osadnik, H.; Campbell, E. A.; Myers, K. S.; Donohue, T. J.; Gross, C. A.
10.1101/2020.06.23.168245 — systems biology — Posted on 2020-06-24
1094 Proto-sex locus in large yellow croaker provides insights into early evolution of the sex chromosome
Wang, Z.; Xiao, S.; Cai, M.; Han, Z.; Li, W.; Xie, Y.; Xu, G.; Lin, A.; Zhang, Y.; Ye, K.; Luo, H.; Liao, M.; Han, F.; Liu, X.; Zhang, D.; Wang, Q.; Wang, B.; Li, W.; Li, J.-T.
10.1101/2020.06.23.166249 — evolutionary biology — Posted on 2020-06-24
1099 ReCodLiver0.9: Overcoming challenges in genome-scale metabolic reconstruction of a non-model species
Hanna, E. M.; Zhang, X.; Eide, M.; Fallahi, S.; Furmanek, T.; Yadetie, F.; Zielinski, D. C.; Goksoyr, A.; Jonassen, I.
10.1101/2020.06.23.162792 — systems biology — Posted on 2020-06-24
1100 Non-invasive Amelioration of Essential Tremor via Phase-Locked Disruption of its Temporal Coherence
Schreglmann, S. R.; Wang, D.; Peach, R. L.; Li, J.; Zhang, X.; Latorre, A.; Rhodes, E.; Panella, E.; Boyden, E.; Barahona, M.; Santaniello, S.; Bhatia, K. P.; Rothwell, J.; Grossman, N.
10.1101/2020.06.23.165498 — neuroscience — Posted on 2020-06-24
1104 Gene Regulatory Network Inference as Relaxed Graph Matching
Weighill, D.; Guebila, M. B.; Lopes-Ramos, C.; Glass, K. M.; Quackenbush, J.; Platig, J.; Burkholz, R.
10.1101/2020.06.23.167999 — bioinformatics — Posted on 2020-06-24
1107 Rapid molecular evolution of Spiroplasma symbionts of Drosophila
Gerth, M.; Martinez Montoya, H.; Ramirez, P.; Masson, F.; Griffin, J. S.; Aramayo, R.; Siozios, S.; Lemaitre, B.; Mateos, M.; Hurst, G. D.
10.1101/2020.06.23.165548 — evolutionary biology — Posted on 2020-06-24
1109 A predictive model of gene expression reveals the role of regulatory motifs in the mating response of yeast
Pomeroy, A. E.; Pena, M. I.; Houser, J. R.; Dixit, G.; Dohlman, H. G.; Elston, T. C.; Errede, B.
10.1101/2020.06.23.167205 — systems biology — Posted on 2020-06-24
1110 Genetic and Genomic Resources to Study Natural Variation in Brassica rapa
Lou, P.; Woody, S.; Greenham, K.; vanBuren, R.; Colle, M.; Edger, P. P.; Sartor, R.; Zheng, Y.; Levendoski, N.; Lim, J.; So, C.; Stoveken, B. J.; Woody, T.; Zhao, J.; Shen, S.; Amasino, R. M.; McClung, C. R.
10.1101/2020.06.23.167270 — plant biology — Posted on 2020-06-24
1111 Cogno-Vest: A Torso-Worn, Force Display to Experimentally Induce Specific Hallucinations and Related Bodily Sensations
Fadaei Jouybari, A.; Jeanmonod, K.; Bleuler, H.; Potheegadoo, J.; Kannape, O. A.; Hara, M.; Blanke, O.
10.1101/2020.06.23.167551 — neuroscience — Posted on 2020-06-24
1112 Elevated somatic mutation burdens in normal human cells due to defective DNA polymerases
Robinson, P. S.; Coorens, T. H. H.; Palles, C.; Mitchell, E.; Abascal, F.; Olafsson, S.; Lee, B.; Lawson, A. R. J.; Lee-Six, H.; Moore, L.; Sanders, M. A.; Hewinson, J.; Martin, L.; Pinna, C. M. A.; Galvotti, S.; Campbell, P. J.; Martincorena, I.; Tomlinson, I.; Stratton, M.
10.1101/2020.06.23.167668 — genomics — Posted on 2020-06-24
1113 Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of purine nucleotide cycle driven fumarate accumulation
Sinton, M. C.; Lucendo Villarin, B.; Meseguer Ripolles, J.; Wernig-Zorc, S.; Thomson, J. P.; Walker, P. D.; Thakker, A.; Ludwig, C.; Tennant, D. A.; Hay, D. C.; Drake, A.
10.1101/2020.06.23.166728 — biochemistry — Posted on 2020-06-24
1114 Transcriptomic and proteomic regulation through abundant, dynamic, and independent arginine methylation by Type I and Type II PRMTs
Lehman, S. M.; Chen, H.; Burgos, E. S.; Maron, M.; Gayatri, S.; Nieves, E.; Bai, D. L.; Sidoli, S.; Gupta, V.; Marunde, M. R.; Bone, J. R.; Sun, Z.-W.; Bedford, M. T.; Shabanowitz, J.; Hunt, D. F.; Shechter, D.
10.1101/2020.06.23.167601 — molecular biology — Posted on 2020-06-24
1115 Constraints on the Efficiency of Electromicrobial Production
Salimijazi, F.; Kim, J.; Schmitz, A. M.; Grenville, R.; Bocarsly, A. B.; Barstow, B.
10.1101/2020.06.23.167288 — synthetic biology — Posted on 2020-06-24
1116 Spatiotemporal brain dynamics during recognition of the music of Johann Sebastian Bach
Bonetti, L.; Brattico, E.; Carlomagno, F.; Cabral, J.; Stevner, A.; Deco, G.; Whybrow, P. C.; Pearce, M.; Pantazis, D.; Vuust, P.; Kringelbach, M. L.
10.1101/2020.06.23.165191 — neuroscience — Posted on 2020-06-24
1117 Identification and characterization of centromeric sequences in Xenopus laevis
Smith, O. K.; Limouse, C.; Fryer, K. A.; Teran, N. A.; Sundararajan, K.; Heald, R.; Straight, A. F.
10.1101/2020.06.23.167643 — genomics — Posted on 2020-06-24
1122 DGAT1 is a lipid metabolism oncoprotein that enables cancer cells to accumulate fatty acid while avoiding lipotoxicity
Wilcock, D. J.; Badrock, A. P.; Owen, R.; Guerin, M.; Southam, A. D.; Johnston, H.; Ogden, S.; Fullwood, P.; Watson, J.; Ferguson, H.; Haworth, J.; Richardson, D. A.; Lloyd, G. R.; Jankevics, A.; Dunn, W. B.; Wellbrock, C.; Lorigan, P.; Ceol, C.; Francavilla, C.; Smith, M. P.; Hurlstone, A. F. L.
10.1101/2020.06.23.166603 — cancer biology — Posted on 2020-06-24
1126 One score to rule them all: severity assessment in laboratory mice
Talbot, S. R.; Struve, B.; Wassermann, L.; Heider, M.; Weegh, N.; Knape, T.; Hofmann, M.; von Knethen, A.; Jirkof, P.; Keubler, L.; Bleich, A.; Haeger, C.
10.1101/2020.06.23.166801 — animal behavior and cognition — Posted on 2020-06-24
1129 Replay bursts coincide with activation of the default mode and parietal alpha network
Higgins, C. J.; Liu, Y. J.; Vidaurre, D.; Kurth-Nelson, Z.; Dolan, R. J.; Behrens, T. E. J.; Woolrich, M. W.
10.1101/2020.06.23.166645 — neuroscience — Posted on 2020-06-24
1131 Reduced nuclear lamin A/C enhances cancer cell squeezing through rigid barriers, does not facilitate endothelial crossing, and impairs experimental metastasis
Roncato, F.; Regev, O.; Feigelson, S. W.; Yadav, S. K.; Kaczmarczyk, L.; Levi, N.; Drago-Garcia, D.; Ovadia, S.; Kizner, M.; Addadi, Y.; Sabino, J. C.; Ovadya, Y.; de Almeida, S. F.; Feldmesser, E.; Gerlitz, G.; Alon, R.
10.1101/2020.06.23.167130 — cancer biology — Posted on 2020-06-24
1134 Nanoparticle Tracking Analysis: A powerful tool for characterizing magnetosome preparations
Fernandez-Castane, A.; Li, h.; Joseph, S.; Ebeler, M.; Franzreb, M.; Bravcewell, D. G.; Overton, T. W.; Thomas, O. R.
10.1101/2020.06.23.166587 — bioengineering — Posted on 2020-06-24
1136 Prelimbic-dependent activation of amygdala somatostatin interneurons signals non-aversive cues to promote discrimination.
Stujenske, J. M.; O'Neill, P.-K.; Nahmoud, I.; Goldberg, S.; Diaz, L.; Labkovich, M.; Hardin, W.; Bolkan, S. S.; Reardon, T. R.; Spellman, T. J.; Salzman, C. D.; Gordon, J. A.; Likhtik, E.
10.1101/2020.06.23.156018 — neuroscience — Posted on 2020-06-24
1137 Predicting Vibrio cholerae infection and disease severity using metagenomics in a prospective cohort study
Levade, I.; Saber, M. M.; Midani, F. S.; Chowdhury, F.; Khan, A. I.; Begum, Y.; Ryan, E. T.; David, L. A.; Calderwood, S. B.; Harris, J. B.; LaRocque, R. C.; Qadri, F.; Shapiro, B. J.; Weil, A. A.
10.1101/2020.02.25.960930 — microbiology — Posted on 2020-06-24
1138 Revealing grand-paternal programming of lipid metabolism using a novel computational tool
Furse, S.; Watkins, A.; Chiarugi, D.; Hojat, N.; Smith, J.; Williams, H.; Koulman, A.
10.1101/2020.06.23.166819 — developmental biology — Posted on 2020-06-24
1139 epiGBS2: an improved protocol and automated snakemake workflow for highly multiplexed reduced representation bisulfite sequencing
Gawehns, F.; Postuma, M.; van Gurp, T. P.; Wagemaker, N. C. A. M.; Fatma, S.; Van Antro, M.; Mateman, C.; Milanovic-Ivanovic, S.; van Oers, K.; Grosse, I.; Vergeer, P.; Verhoeven, K. J. F.
10.1101/2020.06.23.137091 — bioinformatics — Posted on 2020-06-24
1142 A novel Enterococcus faecalis heme transport regulator (FhtR) is a heme sensor in the gastrointestinal tract.
Saillant, V.; Lipuma, D.; Ostyn, E.; Joubert, L.; Boussac, A.; Guerin, H.; Brandelet, G.; Arnoux, P.; Lechardeur, D.
10.1101/2020.06.22.166298 — microbiology — Posted on 2020-06-24
1144 Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries
Kwong, A.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Blackwell, T. W.; TOPMed Analysis Working Group, ; LeFaive, J.; de Andrade, M.; Barnard, J.; Barnes, K. C.; Blangero, J.; Boerwinkle, E.; Burchard, E. G.; Cade, B. E.; Chasman, D.; Chen, H.; Conomos, M.; Cupples, L. A.; Ellinor, P. T.; Eng, C.; Gao, Y.; Guo, X.; Irvin, M. R.; Kelly, T.; Kim, W.; Kooperberg, C.; Lubitz, S. A.; Mak, A. C. Y.; Manichaikul, A. W.; Mathias, R. A.; Montasser, M. E.; Montgomery, C. G.; Musani, S.; Palmer, N. D.; Peloso, G.; Qiao, D.; Reiner, A. P.; Roden, D. M.; Shoemaker, M. B.; Smith, J. A
10.1101/2020.06.23.167759 — bioinformatics — Posted on 2020-06-24
1153 Diversification of DNA-binding specificity via permissive and specificity-switching mutations in the ParB/Noc protein family
Jalal, A. S. B.; Tran, N. T.; Stevenson, C. E.; Chan, E. W.; Lo, R.; Tan, X.; Noy, A.; Lawson, D. M.; Le, T. B. K.
10.1101/724823 — microbiology — Posted on 2020-06-24
1156 Fine-scale ecological and transcriptomic data reveal niche differentiation of an allopolyploid from diploid parents in Cardamine
Akiyama, R.; Sun, J.; Hatakeyama, M.; Lischer, H. E. L.; Briskine, R. V.; Hay, A.; Gan, X.; Tsiantis, M.; Kudoh, H.; Kanaoka, M. M.; Sese, J.; Shimizu, K. K.; Shimizu-Inatsugi, R.
10.1101/600783 — plant biology — Posted on 2020-06-24
1159 Environment-dependent behavioral traits and experiential factors shape addiction vulnerability
Fouyssac, M.; Puaud, M.; Ducret, E.; Marti-Prats, L.; Vanhille, N.; Ansquer, S.; Zhang, X.; Belin-Rauscent, A.; Giuliano, C.; Houeto, J.-L.; Everitt, B.; Belin, D.
10.1101/2020.04.12.038141 — neuroscience — Posted on 2020-06-24
1160 The development of attentional control mechanisms in multisensory environments
Turoman, N.; Tivadar, R. I.; Retsa, C.; Maillard, A. M.; Scerif, G.; Matusz, P. J.
10.1101/2020.06.23.166975 — neuroscience — Posted on 2020-06-24
1164 White Matter microstructural property decoding from gradient echo data using realistic white matter models
Hedouin, R.; Metere, R.; Chan, K.-S.; Licht, C.; Mollink, J.; van Cappellen van Walsum, A.-M.; Marques, J. P.
10.1101/2020.06.23.127258 — neuroscience — Posted on 2020-06-24
1170 The proteomic landscape of centromeric chromatin reveals an essential role for the Ctf19CCAN complex in meiotic kinetochore assembly
Borek, W. E.; Vincenten, N.; Duro, E.; Makrantoni, V.; Spanos, C.; Sarangapani, K. K.; de Lima Alves, F.; Kelly, D. A.; Asbury, C. L.; Rappsilber, J.; Marston, A. L.
10.1101/2020.06.23.167395 — cell biology — Posted on 2020-06-24
1173 Modeling a co-culture of Clostridium autoethanogenum and Clostridium kluyveri to increase syngas conversion to medium-chain fatty-acids
Benito-Vaquerizo, S.; Diender, M.; Parera, I.; Martins dos Santos, V.; Schaap, P. J.; Sousa, D. Z.; Suarez-Diez, M.
10.1101/2020.06.23.167189 — synthetic biology — Posted on 2020-06-24
1175 SUPER RESOLUTION MICROSCOPY AND DEEP LEARNING IDENTIFY ZIKA VIRUS REORGANIZATION OF THE ENDOPLASMIC RETICULUM
Long, R. K. M.; Moriarty, K. P.; Cardoen, B.; Gao, G.; Vogl, A. W.; Jean, F.; Hamarneh, G.; Nabi, I. R.
10.1101/2020.05.12.091611 — cell biology — Posted on 2020-06-23
1176 The buds of Oscarella lobularis (Porifera): a new convenient model for sponge cell and developmental biology
Rocher, C.; Vernale, A.; Fierro-Constain, L.; Sejourne, N.; Chenesseau, S.; Marschal, C.; Le Golf, E.; Dutilleul, M.; Matthews, C.; Marschal, F.; Brouilly, N.; Massey-Harroche, D.; Ereskovsky, A.; Le Bivic, A.; Borchiellini, C.; Renard, E.
10.1101/2020.06.23.167296 — zoology — Posted on 2020-06-23
1179 The CRISPR-Cas9 crGART HeLa transcriptome: A novel cell model of de novo purine synthesis deficiency
Mazzarino, R. C.; Veronika, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.06.23.167924 — cell biology — Posted on 2020-06-23
1181 Neural representation of linguistic feature hierarchy reflects second-language proficiency
Di Liberto, G.; Nie, J.; Yeaton, J.; Khalighinejad, B.; Shamma, S.; Mesgarani, N.
10.1101/2020.06.15.142554 — neuroscience — Posted on 2020-06-23
1183 Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis
Yang, J.; McGovern, A.; Martin, P.; Duffus, K.; Ge, X.; Zarrineh, P.; Morris, A. P.; Adamson, A.; Fraser, P.; Rattray, M.; Eyre, S.
10.1101/827923 — genomics — Posted on 2020-06-23
1186 A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia
da Silva-Diz, V.; Cao, B.; Lancho, O.; Chiles, E.; Alasadi, A.; Luo, S.; Augeri, D.; Minuzzo, S.; Indraccolo, S.; Su, X.; Jin, S.; Herranz, D.
10.1101/2020.06.23.168005 — cancer biology — Posted on 2020-06-23
1187 Characterization of a gene-trap knockout mouse model of Scn2a encoding voltage-gated sodium channel Nav1.2
Eaton, M.; Zhang, J.; Ma, Z.; Park, A. C.; Lietzke, E. E.; Romero, C. M.; Liu, Y.; Coleman, E. R.; Chen, X.; Xiao, T.; Huang, Z.; Skarnes, W. C.; Koss, W. A.; Yang, Y.
10.1101/2020.06.23.150367 — neuroscience — Posted on 2020-06-23
1193 Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1
Brownstein, Z.; Gulsuner, S.; Walsh, T.; Martins, F. T. A.; Taiber, S.; Isakov, O.; Lee, M.; Bordeynik-Cohen, M.; Birkan, M.; Chang, W.; Casadei, S.; Danial-Farran, N.; Abu Rayyan, A.; Carlson, R.; Kamal, L.; Arnporsson, A. O.; Sokolov, M.; Gilony, D.; Lipschitz, N.; Frydman, M.; Davidov, B.; Macarov, M.; Sagi, M.; Vinkler, C.; Poran, H.; Sharony, R.; Samara, N.; Zvi, N.; Baris-Feldman, H.; Singer, A.; Handzel, O.; Hertzano, R.; Ali-Naffaa, D.; Ruhrman-Shahar, N.; Madgar, O.; Sofrin, E.; Peleg, A.; Khayat, M.; Shohat, M.; Basel-Salmon, L.; Pras, E.; Lev, D.; Wolf, M.; Steingrimsson, E.; Shomro
10.1101/2020.06.11.144790 — genetics — Posted on 2020-06-23
1196 Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats
Sajko, S.; Grishkovskaya, I.; Kostan, J.; Graewert, M.; Setiawan, K.; Truebestein, L.; Niedermuller, K.; Gehin, C.; Sponga, A.; Puchinger, M.; Gavin, A.-C.; Leonard, T.; Svergun, D. I.; Smith, T. K.; Morriswood, B. C.; Djinovic-Carugo, K.
10.1101/826180 — biochemistry — Posted on 2020-06-23
1198 Genetic structure and molecular diversity of Brazilian grapevine germplasm: management and use in breeding programs
de Oliveira, G. L.; de Souza, A. P.; de Oliveira, F. A.; Zucchi, M. I.; de Souza, L. M.; Moura, M. F.
10.1101/2020.05.05.078865 — molecular biology — Posted on 2020-06-23
1204 Neurotrophic Factor-Laden Acellular Chondroitin Sulfate Scaffolds Promote Chronic Functional Recovery After Severe Traumatic Brain Injury
Latchoumane, C.-F. V.; Betancur, M. I.; Simchick, G.; Sun, M. K.; Forghani, R.; Lenear, C.; Ahmed, A.; Mohankumar, R.; Balaji, N.; Mason, H. D.; Holmes, P. V.; Zhao, Q.; Bellamkonda, R.; Karumbaiah, L.
10.1101/2020.06.21.116970 — bioengineering — Posted on 2020-06-23
1205 An implant for long-term cervical vagus nerve stimulation in mice
Mughrabi, I. T.; Hickman, J.; Jayaprakash, N.; Papadoyannis, E. S.; Abbas, A.; Chang, Y.-C.; Lee, S.; Datta-Chaudhuri, T.; Chang, E. H.; Zanos, T. P.; Froemke, R. C.; Welle, C.; Al-Abed, Y.; Zanos, S.
10.1101/2020.06.20.160473 — bioengineering — Posted on 2020-06-23
1206 Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of PKA
Roger, F.; Picazo, C.; Reiter, W.; Libiad, M.; Asami, C.; Hanzen, S.; Gao, C.; Lagniel, G.; Welkenhuysen, N.; Labarre, J.; Nyström, T.; Grotli, M.; Hartl, M.; Toledano, M. B.; Molin, M.
10.1101/676270 — biochemistry — Posted on 2020-06-23
1208 Dopa decarboxylase is a genetic hub of parental control over offspring behavior
Bonthuis, P. J.; Steinwand, S.; Huang, W.-C.; Horndli, C. N. S.; Emery, J.; Kravitz, S.; Ferris, E.; Gregg, C.
10.1101/2020.06.23.168195 — neuroscience — Posted on 2020-06-23
1211 A widely-distributed HIV-1 provirus elimination assay to evaluate latency-reversing agents in vitro
Matsuda, K.; Islam, S.; Takada, T.; Tsuchiya, K.; Tan, B. J. Y.; Hattori, S.-i.; Katsuya, H.; Kitagawa, K.; Kim, K. S.; Matsuo, M.; Delino, N. S.; Gatanaga, H.; Yoshimura, K.; Matsushita, S.; Mitsuya, H.; Iwami, S.; Satou, Y.; Maeda, K.
10.1101/842419 — microbiology — Posted on 2020-06-23
1214 The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model for ATIC deficiency and ZMP accumulation
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.04.28.067066 — cell biology — Posted on 2020-06-23
1215 Searching for a UV-filter in the eyes of high flying birds
Zawadzka, M.; Racz, B.; Ambrosini, D.; Gorbitz, C. H.; Morth, J. P.; Lundanes, E.; Rise, F.; Ringvold, A.; Wilson, S. R.; Wilkins, A.; Presto Elgstoen, K. B.; Osteby, A.
10.1101/336644 — biochemistry — Posted on 2020-06-23
1218 Trypanocidal activity of the anthocyanidin delphinidin, a non-competitive inhibitor of arginine kinase
Valera-Vera, E.; Reigada, C.; Saye, M.; Digirolamo, F. A.; Galceran, F.; Miranda, M. R.; Pereira, C. A.
10.1101/2020.06.23.167452 — microbiology — Posted on 2020-06-23
1223 A FIJI Macro for quantifying pattern in extracellular matrix
Wershof, E.; Park, D.; Barry, D. J.; Jenkins, R. P.; Rullan, A.; Wilkins, A.; Roxanis, I.; Anderson, K. I.; Bates, P. A.; Sahai, E.
10.1101/867507 — cancer biology — Posted on 2020-06-23
1225 Modeling the effect of COVID-19 disease on the cardiac function: a computational study
Regazzoni, F.; Vergara, C.; Dede', L.; Zunino, P.; Guglielmo, M.; Scrofani, R.; Fusini, L.; Cogliati, C.; Pontone, G.; Quarteroni, A.
10.1101/2020.06.23.166421 — pathology — Posted on 2020-06-23
1226 Network dynamics underlying OFF responses in the auditory cortex
Bondanelli, G.; Deneux, T.; Bathellier, B.; Ostojic, S.
10.1101/810655 — neuroscience — Posted on 2020-06-23
1228 Capsaicin inhibits arginine kinase and exerts anti-Trypanosoma cruzi activity
Valera-Vera, E.; Reigada, C.; Saye, M.; Digirolamo, F. A.; Miranda, M. R.; Pereira, C. A.
10.1101/2020.06.23.167346 — microbiology — Posted on 2020-06-23
1229 Use of multivariable Mendelian randomization to address biases due to competing risk before recruitment
Schooling, C. M.; Lopez, P. M.; Yang, Z.; Zhao, J. V.; Au Yeung, S.; Huang, J. V.
10.1101/716621 — genetics — Posted on 2020-06-23
1231 Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations
Bengtsen, T.; Holm, V. L.; Kjolbye, L. R.; Midtgaard, S. R.; Johansen, N. T.; Tesei, G.; Bottaro, S.; Schiott, B.; Arleth, L.; Lindorff-Larsen, K.
10.1101/734822 — biophysics — Posted on 2020-06-23
1232 The crystal structure of the Ca2+-ATPase 1 from Listeria monocytogenes reveals a pump primed for dephosphorylation
Basse Hansen, S.; Dyla, M.; Neumann, C. M. T.; Lauwring Andersen, J.; Kjaergaard, M.; Nissen, P.
10.1101/2020.06.23.166462 — biochemistry — Posted on 2020-06-23
1234 Accommodating individual travel history, global mobility, and unsampled diversity in phylogeography: a SARS-CoV-2 case study.
Lemey, P.; Hong, S.; Hill, V.; Baele, G.; Poletto, C.; Colizza, V.; O'Toole, A.; McCrone, J. T.; Andersen, K. G.; Worobey, M.; Nelson, M. I.; Rambaut, A.; Suchard, M. A.
10.1101/2020.06.22.165464 — evolutionary biology — Posted on 2020-06-23
1238 ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways
Treveil, A.; Bohar, B.; Sudhakar, P.; Gul, L.; Csabai, L.; Olbei, M.; Poletti, M.; Madgwick, M.; Andrighetti, T.; Hautefort, I.; Modos, D.; Korcsmaros, T.
10.1101/2020.06.23.167254 — systems biology — Posted on 2020-06-23
1240 SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
Klein, S.; Cortese, M.; Winter, S. L.; Wachsmuth-Melm, M.; Neufeldt, C. J.; Cerikan, B.; Stanifer, M. L.; Boulant, S.; Bartenschlager, R.; Chlanda, P.
10.1101/2020.06.23.167064 — microbiology — Posted on 2020-06-23
1241 RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
Subramanian, A.; Vernon, K.; Slyper, M.; Waldman, J.; Luecken, M. D.; Gosik, K.; Dubinsky, D.; Cuoco, M.; Keller, K.; Purnell, J.; Nguyen, L.; Dionne, D.; Rozenblatt-Rosen, O.; Weins, A.; Human Cell Atlas Lung Biological Network, ; Regev, A.; Greka, A.
10.1101/2020.06.23.167098 — genomics — Posted on 2020-06-23
1243 Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes
Zhou, T.; Teng, I.-T.; Olia, A. S.; Cerutti, G.; Gorman, J.; Nazzari, A.; Shi, W.; Tsybovsky, Y.; Wang, L.; Wang, S.; Zhang, B.; Zhang, Y.; Katsamba, P. S.; Petrova, Y.; Banach, B. B.; Fahad, A. S.; Liu, L.; Lopez Acevedo, S. N.; Madan, B.; Oliveira de Souza, M.; Pan, X.; Wang, P.; Wolfe, J. R.; Yin, M.; Ho, D. D.; Phung, E.; DiPiazza, A.; Chang, L.; Abiona, O.; Corbett, K. S.; DeKosky, B. J.; Graham, B. S.; Mascola, J. R.; Misasi, J.; Ruckwardt, T.; Sullivan, N. J.; Shapiro, L.; Kwong, P. D.
10.1101/2020.06.22.166033 — immunology — Posted on 2020-06-23
1245 A high-quality genome assembly and annotation of the humpback grouper Cromileptes altivelas
Sun, Y.; Zhang, D.; Shi, J.; Chen, G.; Wu, Y.; Shen, Y.; Cao, Z.; Zhang, L.; Zhou, Y.
10.1101/2020.06.22.164277 — genomics — Posted on 2020-06-23
1248 Scalable, rapid and highly sensitive isothermal detection of SARS-CoV-2 for laboratory and home testing
Kellner, M. J.; Ross, J. J.; Schnabl, J.; Dekens, M. P. S.; Heinen, R.; Tanner, N. A.; Fritsche-Polanz, R.; Traugott, M.; Seitz, T.; Zoufaly, A.; Foedinger, M.; Wenisch, C.; Zuber, J.; Vienna Covid-19 Diagnostics Initiative (VCDI), ; Pauli, A.; Brennecke, J.
10.1101/2020.06.23.166397 — molecular biology — Posted on 2020-06-23
1250 Spinal Column Architecture of the Flexible SPP1 Bacteriophage Tail Tube
Zinke, M.; Sachowsky, K.; Oester, C.; Zinn-Justin, S.; Ravelli, R. R.; Schroeder, G. F.; Habeck, M.; Lange, A.
10.1101/2020.06.23.166439 — biophysics — Posted on 2020-06-23
1265 Molecular signaling pathways underlying schizophrenia
Tiihonen, J.; Koskuvi, M.; Lähteenvuo, M.; Trontti, K.; Ojansuu, I.; Vaurio, O.; Cannon, T. D.; Lönnqvist, J.; Therman, S.; Suvisaari, J.; Cheng, L.; Tanskanen, A.; Taipale, H.; Lehtonen, S.; Koistinaho, J.
10.1101/2020.06.23.156653 — neuroscience — Posted on 2020-06-23
1268 Disentangling the biological information encoded in disordered mitochondrial morphology through its rapid elicitation by iCMM
Miyamoto, T.; Uosaki, H.; Mizunoe, Y.; Goto, S.; Yamanaka, D.; Masuda, M.; Yoneyama, Y.; Nakamura, H.; Hattori, N.; Takeuchi, Y.; Sekiya, M.; Matsuzaka, T.; Hakuno, F.; Takahashi, S.-i.; Yahagi, N.; Ito, K.; Shimano, H.
10.1101/2020.06.22.166165 — synthetic biology — Posted on 2020-06-23
1269 Fatty acid photodecarboxylase is an ancient photoenzyme responsible for hydrocarbon formation in the thylakoid membranes of algae
Moulin, S. L. Y.; Beyly, A.; Blangy, S.; Legeret, B.; Floriani, M.; Burlacot, A.; Sorigue, D.; Li-Beisson, Y.; Peltier, G.; Beisson, F.
10.1101/2020.06.23.166330 — plant biology — Posted on 2020-06-23
1270 Spatiotemporal brain dynamics during recognition of the music of Johann Sebastian Bach
Bonetti, L.; Brattico, E.; Carlomagno, F.; Cabral, J.; Stevner, A.; Deco, G.; Whybrow, P. C.; Pearce, M.; Pantazis, D.; Kringelbach, M. L.
10.1101/2020.06.23.165191 — neuroscience — Posted on 2020-06-23
1275 Gene expression imputation provides insight into the genetic architecture of frontotemporal dementia
Reus, L. M.; Pasaniuc, B.; Posthuma, D.; Boltz, T.; International FTD-Genomics Consortium (IFGC), ; Pijnenburg, Y. A. L.; Ophoff, R. A.
10.1101/2020.06.23.166355 — genetics — Posted on 2020-06-23
1276 Defining the lineage of thermogenic perivascular adipose tissue
Angueira, A. R.; Sakers, A. P.; Cheng, L.; Shrestha, R.; Okada, C.; Batmanov, K.; Susztak, K.; Seale, P.
10.1101/2020.06.23.164772 — developmental biology — Posted on 2020-06-23
1280 CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells
Amraei, R.; Napoleon, M.; Yin, W.; Berrigan, J.; Suder, E.; Zhao, G.; Olejnik, J.; Gummuluru, S.; Muhlberger, E.; Chitalia, V.; Rahimi, N.
10.1101/2020.06.22.165803 — cell biology — Posted on 2020-06-23
1282 A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Shi, P.-Y.; Xie, X.; Muruato, A. E.; Zhang, X.; Lokugamage, K. G.; Fontes-Garfias, C. R.; Zou, J.; Liu, J.; Ren, P.; Balakrishnan, M.; Cihlar, T.; Tseng, C.-T. K.; Makino, S.; Menachery, V. D.; Bilello, J. P.
10.1101/2020.06.22.165712 — microbiology — Posted on 2020-06-23
1283 Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Custodio, T. F.; Das, H.; Sheward, D. J.; Hanke, L.; Pazicky, S.; Pieprzyk, J.; Sorgenfrei, M.; Schroer, M.; Gruzinov, A.; Jeffries, C.; Graewert, M.; Svergun, D. I.; Dobrev, N.; Remans, K.; Seeger, M.; McInerney, G. M.; Murrell, B.; Hällberg, B. M.; Löw, C.
10.1101/2020.06.23.165415 — biophysics — Posted on 2020-06-23
1284 A graph-based approach identifies dynamic H-bond communication networks in spike protein S of SARS-CoV-2
Karathanou, K.; Lazaratos, M.; Bertalan, E.; Siemers, M.; Buzar, K.; Schertler, G. F. X.; del Val, C.; Bondar, A.-N.
10.1101/2020.06.23.164947 — bioinformatics — Posted on 2020-06-23
1285 Expression of Ace2, Tmprss2, and Furin in mouse ear tissue
Uranaka, T.; Kashio, A.; Ueha, R.; Sato, T.; Han, B.; Gao, Y.; Kinoshita, M.; Kondo, K.; Yamasoba, T.
10.1101/2020.06.23.164335 — microbiology — Posted on 2020-06-23
1293 Functional characterization of RNase H1 proteins in Arabidopsis thaliana
Kucinski, J.; Kmera, A.; Rowley, M. J.; Khurana, P.; Nowotny, M.; Wierzbicki, A. T.
10.1101/662080 — plant biology — Posted on 2020-06-23
1294 Analytical guidelines to increase the value of citizen science data: using eBird data to estimate species occurrence
Johnston, A.; Hochachka, W. M.; Strimas-Mackey, M.; Ruiz Gutierrez, V.; Robinson, O. J.; Miller, E. T.; Auer, T.; Kelling, S. T.; Fink, D.
10.1101/574392 — ecology — Posted on 2020-06-23
1299 Online Transcranial Random Noise stimulation improves perception at high levels of visual white noise
Melnick, M. D.; Park, W. J.; Croom, S.; Chen, S.; Battelli, L.; Busza, A.; Huxlin, K. R.; Tadin, D.
10.1101/2020.06.22.165969 — neuroscience — Posted on 2020-06-23
1301 Ultra-compact Dual-band Smart NEMS Magnetoelectric Antennas for Simultaneous Wireless Energy Harvesting and Magnetic Field Sensing
Zaeimbashi, M.; Nasrollahpour, M.; Khalifa, A.; Romano, A.; Liang, X.; Chen, H.; Sun, N.; Matyushov, A.; Lin, H.; Dong, C.; Xu, Z.; Mittal, A.; Martos-Repath, I.; Jha, G.; Mirchandani, N.; Das, D.; Onabajo, M.; Shrivastava, A.; Cash, S.; Sun, N.
10.1101/2020.06.22.165894 — bioengineering — Posted on 2020-06-23
1302 Monitoring the collective behavior of enzymatic nanomotors in vitro and in vivo by PET-CT
Hortelao, A. C.; Simo, C.; Guix, M.; Guallar-Garrido, S.; Julian, E.; Vilela, D.; Rejc, L.; Ramos-Cabrer, P.; Cossio, U.; Gomez-Vallejo, V.; Patino, T.; Llop, J.; Sanchez, S.
10.1101/2020.06.22.146282 — bioengineering — Posted on 2020-06-23
1304 Topographic profiling of memory-related pattern separation processes in humans
Li, Q.; Tavakol, S.; Royer, J.; Lariviere, S.; Vos de Wael, R.; Park, B.-y.; Paquola, C.; Caldairou, B.; Bassett, D. S.; Bernasconi, A.; Bernasconi, N.; Frauscher, B.; Smallwood, J.; Caciagli, L.; Li, S.; Bernhardt, B.
10.1101/2020.06.22.165290 — neuroscience — Posted on 2020-06-23
1307 Controlling protein nanocage assembly with hydrostatic pressure
Le Vay, K. K.; Carter, B. M.; Watkins, D. W.; Tang, T.-Y. D.; Ting, V. P.; Cölfen, H.; Rambo, R. P.; Smith, A. J.; Anderson, J. L. R.; Perriman, A. W.
10.1101/2020.06.16.154534 — biophysics — Posted on 2020-06-23
1312 Macroscale connectome manifold expansion in adolescence
Park, B.-y.; Bethlehem, R. A. I.; Paquola, C.; Lariviere, S.; Cruces, R. R.; Vos de Wael, R.; Neuroscience in Psychiatry Network (NSPN) Consortium, ; Bullmore, E. T.; Bernhardt, B.
10.1101/2020.06.22.165621 — neuroscience — Posted on 2020-06-23
1314 Wetland plant evolutionary history influences soil and endophyte microbial community composition
Szubryt, M. B.; Skinner, K.; O'Loughlin, E. J.; Koval, J.; Greenwald, S. M.; Owens, S. M.; Kemner, K. M.; Weisenhorn, P. B.
10.1101/2020.06.22.165738 — ecology — Posted on 2020-06-23
1315 Snf1p/Hxk2p/Mig1p pathway regulates exponential growth, mitochondrial respiration, and hexose transporters transcription in Saccharomyces cerevisiae
Carrillo-Garmendia, A.; Martinez-Ortiz, C.; Martinez-Garfias, J. G.; Gonzalez-Hernandez, J. C.; Nava, G. M.; Ramos-Gomez, M.; Dufoo-Hurtado, M. D.; Madrigal-Perez, L. A.
10.1101/2020.06.22.165753 — biochemistry — Posted on 2020-06-23
1320 b3galt6 knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region
Delbaere, S.; De Clercq, A.; Mizumoto, S.; Noborn, F.; Bek, J. W.; Alluyn, L.; Gistelinck, C.; Syx, D.; Salmon, P. L.; Coucke, P. J.; Larson, G.; shuhei, Y.; Willaert, A.; Malfait, F.
10.1101/2020.06.22.165316 — genetics — Posted on 2020-06-23
1322 Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients
Martignano, F.; Crucitta, S.; Mingrino, A.; Semeraro, R.; Del Re, M.; Petrini, I.; Magi, A.; Conticello, S. G.
10.1101/2020.06.22.165555 — cancer biology — Posted on 2020-06-23
1325 Puromycin reactivity does not accurately localize translation at the subcellular level
Enam, S. U.; Zinshteyn, B.; Goldman, D. H.; Cassani, M.; Livingston, N. M.; Seydoux, G.; Green, R.
10.1101/2020.06.22.165217 — biochemistry — Posted on 2020-06-23
1334 Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Kildisiute, G.; Kholosy, W. M.; Young, M. D.; Roberts, K.; Elmentaite, R.; van Hooff, S. R.; Khabirova, E.; Piapi, A.; Thevanesan, C.; Bugallo Blanco, E.; Burke, C.; Mamanova, L.; Lijnzaad, P.; Margaritis, T.; Holstege, F. C. P.; Tas, M. L.; Wijnen, M. H. W. A.; van Noesel, M. M.; del Valle, I.; Barone, G.; van der Linden, R.; Duncan, C.; Anderson, J.; Achermann, J. C.; Haniffa, M.; Teichmann, S. C. P.; Rampling, D.; Sebire, N. J.; He, X.; de Krijger, R. R.; Barker, R. A.; Meyer, K. B.; Bayraktar, O.; Straathof, K.; Molenaar, J. J.; Behjati, S.
10.1101/2020.06.22.164301 — cancer biology — Posted on 2020-06-23
1337 MYC regulates ribosome biogenesis and mitochondrial gene expression programs through interaction with Host Cell Factor-1
Popay, T. M.; Wang, J.; Adams, C. M.; Codreanu, S. G.; Sherrod, S. D.; McLean, J. A.; Thomas, L. R.; Lorey, S. L.; Machida, Y. J.; Weissmiller, A. M.; Eischen, C. M.; Liu, Q.; Tansey, W.
10.1101/2020.06.22.164764 — cancer biology — Posted on 2020-06-23
1340 Life-long telomere attrition predicts health and lifespan in a large mammal
Seeker, L. A.; Underwood, S. L.; Wilbourn, R. V.; Fairlie, J.; Froy, H.; Holland, R.; Ilska, J. J.; Psifidi, A.; Bagnall, A.; Whitelaw, B.; Coffey, M.; Banos, G.; Nussey, D. H.
10.1101/2020.06.22.165563 — evolutionary biology — Posted on 2020-06-23
1342 The germline mutational process in rhesus macaque and its implications for phylogenetic dating
Bergeron, L. A.; Besenbacher, S.; Bakker, J.; Zheng, J.; Li, P.; Pacheco, G.; Sinding, M.-H. S.; Kamilari, M.; Gilbert, M. T. P.; Schierup, M. H.; Zhang, G.
10.1101/2020.06.22.164178 — evolutionary biology — Posted on 2020-06-23
1346 Composite modeling of leaf shape across shoots discriminates Vitis species better than individual leaves
Bryson, A. E.; Wilson Brown, M.; Mullins, J.; Dong, W.; Bahmani, K.; Bornowski, N.; Chiu, C.; Engelgau, P.; Gettings, B.; Gomezcano, F.; Gregory, L. M.; Haber, A. C.; Hoh, D.; Jennings, E. E.; Ji, Z.; Kaur, P.; Kenchanmane Raju, S. K.; Long, Y.; Lotreck, S. G.; Mathieu, D. T.; Ranaweera, T.; Ritter, E. J.; Sadohara, R.; Shrote, R. Z.; Smith, K. E.; Teresi, S. J.; Venegas, J.; Wang, H.; Wilson, M. L.; Tarrant, A. R.; Frank, M. H.; Migicovsky, Z.; Kumar, J.; VanBuren, R.; Londo, J. P.; Chitwood, D. H.
10.1101/2020.06.22.163899 — plant biology — Posted on 2020-06-23
1350 Dot1L interacts with Zc3h10 to activate UCP1 transcription and promote thermogenesis
Yi, D.; Nguyen, H. P.; Dinh, J.; Viscarra, J. A.; Xie, Y.; Dempersmier, J. M.; Wang, Y.; Sul, H. S.
10.1101/2020.06.22.154963 — developmental biology — Posted on 2020-06-23
1351 "3G" Trial: An RNA Editing Signature for Guiding Gastric Cancer Chemotherapy
An, O.; Song, Y.; Ke, X.; So, J. B.-Y.; Sundar, R.; Yang, H.; Rha, S. Y.; Hui, L. M.; Ting, T. S.; Wen, O. X.; Keng, A. T. L.; Ng, M. C. H.; Tantoso, E.; Chen, L.; Tan, P.; Yong, W. P.; Singapore Gastric Cancer Consortium (SGCC),
10.1101/2020.06.22.164038 — cancer biology — Posted on 2020-06-23
1352 New insights on the interaction mechanism of rhTNF with its antagonists Adalimumab and Etanercept
Contreras, M. A.; Macaya, L. A.; Neira, P. J.; Camacho, F.; Gonzalez, A.; Acosta, J.; Montesino, R.; Toledo, J.; Sanchez, O.
10.1101/2020.06.21.163824 — molecular biology — Posted on 2020-06-23
1354 Life history scaling and the division of energy in forests
Grady, J. M.; Read, Q. D.; Record, S.; Ruger, N.; Zarnetske, P. L.; Dell, A. I.; Hubbell, S. P.; Michaletz, S. T.; Shenkin, A.; Enquist, B. J.
10.1101/2020.06.22.163659 — ecology — Posted on 2020-06-23
1355 Long-range neural coherence encodes stimulus information in primate visual cortex
Kermani, M.; Zavitz, E.; Oakley, B.; Price, N. S. C.; Hagan, M. A.; Wong, Y. T.
10.1101/2020.06.22.164269 — neuroscience — Posted on 2020-06-23
1356 Daytime light enhances the amplitude of circadian output in a diurnal mammal
Bano-Otalora, B.; Martial, F.; Harding, C.; Bechtold, D. A.; Allen, A. E.; Brown, T. M.; Belle, M. D. C.; Lucas, R. J.
10.1101/2020.06.22.164194 — neuroscience — Posted on 2020-06-23
1357 Quantifying the wave resistance of a swimmer
Dickson, T.; Turnock, S.; Hudson, D.; Taunton, D.; Banks, J.
10.1101/2020.06.22.164236 — bioengineering — Posted on 2020-06-23
1358 Connectome spectral analysis to track EEG task dynamics on a subsecond scale
Glomb, K.; Rue Queralt, J.; Pascucci, D.; Defferrard, M.; Tourbier, S.; Carboni, M.; Rubega, M.; Vulliemoz, S.; Plomp, G.; Hagmann, P.
10.1101/2020.06.22.164111 — neuroscience — Posted on 2020-06-23
1361 Artificial light at night amplifies seasonal relapse of haemosporidian parasites in a widespread songbird
Becker, D. J.; Singh, D.; Pan, Q.; Montoure, J. D.; Talbott, K. M.; Wanamaker, S.; Ketterson, E. D.
10.1101/2020.06.22.163998 — ecology — Posted on 2020-06-23
1362 Individualised dynamic internal representations from response times
Török, B.; Nagy, D. G.; Kiss, M. M.; Janacsek, K.; Nemeth, D.; Orban, G.
10.1101/2020.06.22.163295 — neuroscience — Posted on 2020-06-23
1363 Salient Safety Conditioning Improves Novel Discrimination Learning
Nahmoud, I.; Ganay Vasquez, J.; Cho, H.; Dennis-Tiwary, T. A.; Likhtik, E.
10.1101/2020.06.22.160465 — neuroscience — Posted on 2020-06-23
1365 Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling
Konopelski, S. E.; Susman, M. W.; Kunz, R. C.; Tan, J.; Cohen, M. D.; Okada, K.; Lamb, H.; Choi, S. S.; Karuna, E. P.; Scales, M. K.; Gygi, S. P.; Greenberg, M. E.; Ho, H.-Y. H.
10.1101/2020.06.22.163790 — developmental biology — Posted on 2020-06-23
1366 The Biomechanical Basis of Biased Epithelial Tube Elongation
Runser, S.; Conrad, L.; Gomez, H.; Lang, C.; Dumont, M.; Sapala, A.; Kramps, L.; Michos, O.; Vetter, R.; Iber, D.
10.1101/2020.06.22.166231 — developmental biology — Posted on 2020-06-23
1367 Organization of DNA replication origin firing in Xenopus egg extracts : the role of intra-S checkpoint
Ciardo, D.; Haccard, O.; Narassimprakash, H.; Arbona, J.-M.; Hyrien, O.; Audit, B.; Marheineke, K.; Goldar, A.
10.1101/2020.06.22.164673 — cell biology — Posted on 2020-06-23
1372 COMPOSITUM 1 (COM1) contributes to the architectural simplification of barley inflorescence via meristem identity signals
Poursarebani, N.; Trautewig, C.; Melzer, M.; Nussbaumer, T.; Lundqvist, U.; Rutten, T.; Schmutzer, T.; Brandt, R.; Himmelbach, A.; Altschmied, L.; Koppolu, R.; Youssef, H. M.; Sibout, R.; Dalmais, M.; Bendahmane, A.; Stein, N.; Xin, Z.; Schnurbusch, T.
10.1101/2020.02.18.952705 — plant biology — Posted on 2020-06-23
1373 Naturalistic coding of working memory in primate prefrontal cortex
Roussy, M.; Luna, R.; Duong, L.; Corrigan, B.; Gulli, R. A.; Nogueira, R.; Moreno-Bote, R.; Sachs, A. J.; Palaniyappan, L.; Martinez-Trujillo, J. C.
10.1101/2020.06.19.162446 — neuroscience — Posted on 2020-06-23
1374 The legacy of recurrent introgression during the radiation of hares
Ferreira, M. S.; Jones, M. R.; Callahan, C. M.; Farelo, L.; Tolesa, Z.; Suchentrunk, F.; Boursot, P.; Mills, L. S.; Alves, P. C.; Good, J. M.; Melo-Ferreira, J.
10.1101/2020.06.19.160283 — evolutionary biology — Posted on 2020-06-23
1375 Sailing in rough waters: examining volatility of fMRI noise
Leppanen, J.; Stone, H.; Lythgoe, D. J.; Williams, S.; Horvath, B.
10.1101/2020.06.19.161570 — neuroscience — Posted on 2020-06-22
1376 Synergistic epistasis enhances cooperativity of mutualistic interspecies interactions
Turkarslan, S.; Stopnisek, N.; Thompson, A. W.; Arens, C. E.; Valenzuela, J. J.; Wilson, J.; Hunt, K. A.; Hardwicke, J.; Lim, S.; Seah, Y. M.; Fu, Y.; Wu, L.; Zhou, J.; Hillesland, K. L.; Stahl, D. A.; Baliga, N. S.
10.1101/2020.06.22.160184 — evolutionary biology — Posted on 2020-06-22
1377 Selective Vulnerability of Senescent Glioblastoma Cells to Bcl-XL Inhibition
Rahman, M.; Olson, I. E.; Mansour, M.; Carlstrom, L. P.; Sutiwisesak, R.; Saber, R.; Rajani, K.; Warrington, A. E.; Howard, A.; Schroeder, M.; Chen, S.; Decker, P. A.; Zhu, Y.; Parney, I. F.; Burma, S.; Brown, D.; Rodriguez, M.; Sarkaria, J. N.; Kirkland, J.; Burns, T.; F. Sananikone, E.
10.1101/2020.06.03.132712 — cancer biology — Posted on 2020-06-22
1379 A novel synthetic peptide provides neuroprotection and rescues rat cortical neurons from anesthetic-induced cell death and modulation of growth and synaptic assembly
Iqbal, F.; Pehar, M.; Thompson, A.; Azeem, U.; Jahanbakhsh, K.; Jimenez-Tellez, N.; Sabouny, R.; Batool, S.; Ibrahim, A.; Chow, J.; Machiraju, P.; Shutt, T.; Yusuf, K.; Shearer, J.; Rice, T.; Syed, N.
10.1101/2020.06.18.159889 — neuroscience — Posted on 2020-06-22
1382 No one-size-fits-all solution to clean GBIF
Zizka, A.; Antunes Carvalho, F.; Calvente, A.; Rocio Baez-Lizarazo, M.; Cabral, A.; Ramos Coelho, J. F.; Colli-Silva, M.; Ramos Fantinati, M.; Ferreira Fernandes, M.; Ferreira-Araujo, T.; Gondim Lambert Moreira, F.; da Cunha Santos, N. M.; Borges Santos, T. A.; Clicia dos Santos-Costa, R.; Cabreirinha Serrano, F.; Alves da Silva, A. P.; Cavalcante de Souza, P. G.; Calisto Tomaz, E.; de Souza Soares, A.; Fonseca Vale, V.; Vieira, T. L.; Antonelli, A.
10.1101/2020.03.12.974543 — ecology — Posted on 2020-06-22
1383 Modeling heterogeneity of Triple-Negative Breast Cancer highlights potency of WEE1 and BCL-XL targeting
Lamballe, F.; Ahmad, F.; Vinik, Y.; Castellanet, O.; Daian, F.; Mueller, A.; Koehler, U.; Bailly, A.-L.; Josselin, E.; Castellano, R.; Cayrou, C.; Charafe-Jauffret, E.; Mills, G. B.; Geli, V.; Borg, J.-P.; Lev, S.; Maina, F.
10.1101/2020.06.22.164418 — cancer biology — Posted on 2020-06-22
1385 TALC: Transcript-level Aware Long Read Correction
Broseus, L.; Thomas, A.; Oldfield, A.; Sevrac, D.; Dubois, E.; Ritchie, W. J.
10.1101/2020.01.10.901728 — bioinformatics — Posted on 2020-06-22
1390 Aberrant claudin-6-adhesion signal promotes endometrial cancer progression via estrogen receptor α
Kojima, M.; Sugimoto, K.; Tanaka, M.; Endo, Y.; Ichikawa-Tomikawa, N.; Kashiwagi, K.; Kato, H.; Honda, T.; Furukawa, S.; Nishiyama, H.; Watanabe, T.; Soeda, S.; Fujimori, K.; Chiba, H.
10.1101/2020.05.15.097659 — cancer biology — Posted on 2020-06-22
1391 A Biophysical Model for Plant Cell Plate Development
Jawaid, M. Z.; Sinclair, R. M.; Cox, D.; Drakakaki, G.
10.1101/2020.05.21.109512 — biophysics — Posted on 2020-06-22
1392 Reduced cue-induced reinstatement of cocaine seeking behavior in Plcb1+/- mice
Cabana-Dominguez, J.; Martin-Garcia, E.; Gallego-Roman, A.; Maldonado, R.; Fernandez-Castillo, N.; Cormand, B.
10.1101/2020.06.18.158964 — animal behavior and cognition — Posted on 2020-06-22
1394 Regenerative neurogenic response from glia requires insulin driven neuron-glia communication
Harrison, N.; Connolly, E.; Gascon Gubieda, A.; Yang, Z.; Altenhein, B.; Losada Perez, M.; Moreira, M.; Hidalgo, A.
10.1101/721498 — neuroscience — Posted on 2020-06-22
1396 Morse-clustering of a Topological Data Analysis Network Identifies Phenotypes of Asthma Based on Blood Gene Expression Profiles
Schofield, J. P. R.; Strazzeri, F.; Bigler, J.; Boedigheimer, M.; Adcock, I. M.; Chung, K. F.; Bansal, A.; Knowles, R.; Dahlen, S.-E.; Wheelock, C. E.; Sun, K.; Pandis, I.; Riley, J.; Auffray, C.; De Meulder, B.; Lefaudeux, D.; Ramanan, D.; Sousa, A. R.; Sterk, P. J.; Ewing, R. M.; MacArthur, B. D.; Djukanovic, R.; Sanchez Garcia, R. J.; Skipp, P. J.
10.1101/516328 — molecular biology — Posted on 2020-06-22
1398 Isolation and characterization of Streptomyces bacteriophages and Streptomyces strains encoding biosynthetic arsenals
Montano, E. T.; Nideffer, J. F.; Brumage, L.; Erb, M.; Derman, A. I.; Davis, J. P.; Estrada, E.; Fu, S.; Le, D.; Vuppala, A.; Tran, C.; Luterstein, E.; Lakkaraju, S.; Panchagnula, S.; Ren, C.; Doan, J.; Tran, S.; Soriano, J.; Fujita, Y.; Gutala, P.; Fujii, Q.; Lee, M.; Bui, A.; Villarreal, C.; Shing, S. R.; Kim, S.; Freeman, D.; Racha, V.; Ho, A.; Kumar, P.; Falah, K.; Dawson, T.; Enustun, E.; Prichard, A.; Gomez, A.; Khanna, K.; Trigg, S.; Pogliano, K.; Pogliano, J.
10.1101/2020.06.22.164533 — microbiology — Posted on 2020-06-22
1399 ADA2 is a lysosomal DNase regulating the type-I interferon response
Greiner-Tollersrud, O. K.; Krausz, M.; Bartok, E.; Boehler, V.; Ebersbach, H.; Baash, S.; Guerini, D.; Hartmann, G.; Huebscher, K.; Kochs, G.; Marchant, M.; Polyzou, A.; Schepp, J.; Seidl, M.; Smulski, C. R.; Staab, D.; Trompouki, E.; Raieli, S.; Olsen, J. O.; Link, R.; Srinivas, H.; Henneke, P.; Geiger, R.; Grimbacher, B.; Warncke, M.; Proietti, M.
10.1101/2020.06.21.162990 — immunology — Posted on 2020-06-22
1400 The First complete Zoroastrian-Parsi Mitochondria Reference Genome: Implications of mitochondrial signatures in an endogamous, non-smoking population
Morawala-Patell, V.; Pasha, N. S.; Krishnasamy, K.; Mittal, B.; Gopalakrishnan, C.; Mugasimangalam, R.; Sharma, N.; Khanna-Gupta, A.; Bhote-Patell, P.; Rao, S. N.; Jain, R.
10.1101/2020.06.05.124891 — genomics — Posted on 2020-06-22
1402 Computationally efficient whole genome regression for quantitative and binary traits
Mbatchou, J.; Barnard, L.; Backman, J.; Marcketta, A.; Kosmicki, J. A.; Ziyatdinov, A.; Benner, C.; O'Dushlaine, C.; Barber, M.; Boutkov, B.; Habegger, L.; Ferreira, M.; Baras, A.; Reid, J. G.; Abecasis, G.; Maxwell, E.; Marchini, J.
10.1101/2020.06.19.162354 — genetics — Posted on 2020-06-22
1403 How do species barriers decay? Concordance and local introgression in mosaic hybrid zones of mussels
Simon, A.; Fraïsse, C.; El Ayari, T.; Liautard-Haag, C.; Strelkov, P.; Welch, J. J.; Bierne, N.
10.1101/818559 — evolutionary biology — Posted on 2020-06-22
1407 Direct and specific assessment of axonal injury and spinal cord microenvironments using diffusion correlation imaging
Benjamini, D.; Hutchinson, E. B.; Komlosh, M. E.; Comrie, C. J.; Schwerin, S. C.; Zhang, G.; Pierpaoli, C.; Basser, P. J.
10.1101/2020.05.04.074856 — neuroscience — Posted on 2020-06-22
1409 Oxazepam and cognitive reappraisal: a randomised experiment
Nilsonne, G.; Tamm, S.; Golkar, A.; Olsson, A.; Sörman, K.; Howner, K.; Kristiansson, M.; Ingvar, M.; Petrovic, P.
10.1101/656355 — neuroscience — Posted on 2020-06-22
1410 The IQGAP1-hnRNPM interaction links tumour-promoting alternative splicing to heat-induced signals
Birladeanu, A.; Rogalska, M.; Potiri, M.; Papadaki, V.; Andreadou, M.; Kontoyiannis, D. L.; Erpapazoglou, Z.; Lewis, J. D.; Kafasla, P.
10.1101/2020.05.11.089656 — molecular biology — Posted on 2020-06-22
1411 PacC-dependent adaptation and modulation of host cellular pH controls hemibiotrophic invasive growth and disease development by the rice blast fungus
Chen, X.-L.; He, D.; Yin, C.; Yang, J.; Sun, J.; Wang, D.; Xue, M.; Li, Z.; Peng, Z.; Chen, D.; Zhao, W.; Xu, J.-R.; Talbot, N. J.; Peng, Y.-L.
10.1101/2020.06.22.164590 — microbiology — Posted on 2020-06-22
1412 Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses
Furtado, R.; Chorro, L.; Zimmerman, N.; Guillen, E.; Spaulding, E.; Chin, S. S.; Daily, J.; Lauvau, G.
10.1101/2020.06.22.164566 — immunology — Posted on 2020-06-22
1416 RND3/RhoE deficiency in preeclamptic women impairs placental mitochondrial function via regulation of the PPARgamma-UCP2 pathway
Yue, X.; Huang, L.; Ma, Y.; Chen, L.; Chang, J.; Zhong, M.; Wang, Z.; Sun, Y.; Chen, X.; Sun, F.; Xiao, L.; Chen, J.; Lai, Y.; Yan, C.; Yu, Y.
10.1101/2020.06.22.164921 — pathology — Posted on 2020-06-22
1420 Role for both myeloid and plasmacytoid DC in driving primary T helper cell response to Burkholderia pseudomallei in healthy individuals.
Reddi, D.; Durant, L.; Bernardo, D.; Noble, A.; English, N. R.; Hendy, P.; Clark, G. C.; Prior, J. L.; Williamson, E. D.; Knight, S. C.
10.1101/2020.06.22.164608 — immunology — Posted on 2020-06-22
1421 All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes
Hughes, A. E.; Hayes, M. G.; Egan, A. M.; Patel, K. A.; Scholtens, D. M.; Lowe, L. P.; Lowe, W. L.; Dunne, F. P.; Hattersley, A. T.; Freathy, R. M.
10.1101/671057 — genetics — Posted on 2020-06-22
1429 Speeding up eQTL scans in the BXD population using GPUs
Trotter, C.; Kim, H.; Farage, G.; Broman, K. W.; Williams, R. W.; Prins, P.; Sen, S.
10.1101/2020.06.22.153742 — genetics — Posted on 2020-06-22
1430 Tissue-specific dynamic codon redefinition in Drosophila
Hudson, A. M. M.; Loughran, G.; Szabo, N. L.; Wills, N. M.; Atkins, J. F.; Cooley, L.
10.1101/2020.06.22.165522 — developmental biology — Posted on 2020-06-22
1432 Keratins couple with the nuclear lamina and regulate proliferation in colonic epithelial cells
Stenvall, C.-G. A.; Nyström, J. H.; Butler-Hallissey, C.; Adam, S. A.; Foisner, R.; Ridge, K. M.; Goldman, R. D.; Toivola, D. M.
10.1101/2020.06.22.164467 — cell biology — Posted on 2020-06-22
1434 Dissection-independent production of a protective whole-sporozoite malaria vaccine
Blight, J.; Sala, K. A.; Atcheson, E.; Kramer, H.; El-Turabi, A.; Real, E.; Dahalan, F. A.; Bettencourt, P.; Dickinson, E.; Alves, E.; Salman, A. M.; Janse, C. J.; Ashcroft, F.; Hill, A. V. S.; Reyes-Sandoval, A.; Blagborough, A. M.; Baum, J.
10.1101/2020.06.22.164756 — microbiology — Posted on 2020-06-22
1437 Calcitriol, the active form of vitamin D, is a promising candidate for COVID-19 prophylaxis
Mok, C. K.; Ng, Y. L.; Ahidjo, B. A.; Lee, R. C. H.; Loe, M. W. C.; Liu, J.; Tan, K. S.; Kaur, P.; Chng, W. J.; Wong, J. E. L.; Wang, D. Y.; Hao, E. W.; Hao, X.; Tan, Y. W.; Mak, T. M.; Lin, C.; Lin, R. V. T. P.; Tambyah, P. A.; Deng, J.; Chu, J. J. H.
10.1101/2020.06.21.162396 — microbiology — Posted on 2020-06-22
1438 In vivo antiviral host response to SARS-CoV-2 by viral load, sex, and age
Lieberman, N. A. P.; Peddu, V.; Xie, H.; Shrestha, L.; Huang, M.; Mears, M. C.; Cajimat, M. N.; Bente, D. A.; Shi, P.-Y.; Bovier, F.; Roychoudhury, P.; Jerome, K. R.; Moscona, A.; Porotto, M.; Greninger, A. L.
10.1101/2020.06.22.165225 — microbiology — Posted on 2020-06-22
1439 Boosting innate immunity: Asaia bacteria expressing a protein from Wolbachia determine macrophage activation and killing of Leishmania parasites
VAROTTO-BOCCAZZI, I.; EPIS, S.; ARNOLDI, I.; CORBETT, Y.; GABRIELI, P.; PARONI, M.; NODARI, R.; BASILICO, N.; SACCHI, L.; GRAMICCIA, M.; GRADONI, L.; TRANQUILLO, V.; Bandi, C.
10.1101/2020.06.22.164145 — microbiology — Posted on 2020-06-22
1440 Mycobacterium tuberculosis complex lineage 5 exhibits high levels of within-lineage genomic diversity
Sanoussi, C. N.; Coscolla, M.; Ofori-Anyinam, A. B.; Otchere, I. D.; Antonio, M.; Niemann, S.; Parkhill, J.; Harris, S.; Yeboah-Manu, D.; Gagneux, S.; Rigouts, L.; Affolabi, D.; de Jong, B. C.; Meehan, C. J.
10.1101/2020.06.22.164186 — genetics — Posted on 2020-06-22
1442 Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of COVID-19 Spike psedotype virus
Wang, N.; Han, S.; Liu, R.; Meng, L.; He, H.; Zhang, Y.; Wang, C.; Lv, Y.; Wang, J.; Li, X.; Ding, Y.; Fu, J.; Hou, Y.; Lu, W.; Ma, W.; Zhan, Y.; Dai, B.; Zhang, J.; Pan, X.; Hu, S.; Gao, J.; Jia, Q.; Zhang, L.; Ge, S.; Wang, S.; Liang, P.; Hu, T.; Lu, J.; Wang, X.; Zhou, H.; Ta, W.; Wang, Y.; Lu, S.; He, L.
10.1101/2020.06.22.164665 — biochemistry — Posted on 2020-06-22
1445 Endemic human coronaviruses induce distinct antibody repertoires in adults and children
Khan, T.; Rahman, M.; Al Ali, F.; Huang, S. S. Y.; Sayeed, A.; Nasrallah, G. K.; Hasan, M. R.; Marr, N.
10.1101/2020.06.21.163394 — immunology — Posted on 2020-06-22
1448 Functional characterization of SARS-CoV-2 infection suggests a complex inflammatory response and metabolic alterations
Trilla-Fuertes, L.; Ramos-Ruiz, R.; Blanca-Lopez, N.; Lopez-Camacho, E.; Martin-Pedraza, L.; Ryan Murua, P.; Diaz-Almiron, M.; Llorens, C.; Gabaldon, T.; Moya, A.; Fresno, J. A.; Gamez-Pozo, A.
10.1101/2020.06.22.164384 — microbiology — Posted on 2020-06-22
1450 PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20
Bancroft, J.; Holder, J.; Geraghty, Z.; Alfonso-Perez, T.; Murphy, D.; Barr, F.; Gruneberg, U.
10.1101/2020.06.22.164251 — cell biology — Posted on 2020-06-22
1451 No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
van Dorp, L.; Richard, D.; Tan, C. C.; Shaw, L. P.; Acman, M.; Balloux, F.
10.1101/2020.05.21.108506 — genomics — Posted on 2020-06-22
1454 SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients
Klimstra, W. B.; Tilston-Lunel, N. L.; Nambulli, S.; Boslett, J.; McMillen, C. M.; Gilliland, T.; Dunn, M. D.; Sun, C.; Wheeler, S. E.; Wells, A.; Hartman, A. L.; McElroy, A. K.; Reed, D. S.; Rennick, L. J.; Duprex, W. P.
10.1101/2020.06.19.154930 — microbiology — Posted on 2020-06-22
1455 Germanium nanospheres for ultraresolution picotensiometry of kinesin motors
Sudhaker, S.; Abdosamadi, M. K.; Jachowski, T. J.; Bugiel, M.; Jannasch, A.; Schäffer, E.
10.1101/2020.06.18.159640 — biophysics — Posted on 2020-06-22
1456 Lineage recording reveals dynamics of cerebral organoid regionalization
He, Z.; Gerber, T.; Maynard, A.; Jain, A.; Petri, R.; Santel, M.; Ly, K.; Sidow, L.; Sanchis Calleja, F.; Riesenberg, S.; Camp, J. G.; Treutlein, B.
10.1101/2020.06.19.162032 — developmental biology — Posted on 2020-06-22
1457 Genetic influences on hub connectivity of the human connectome
Arnatkeviciute, A.; Fulcher, B. D.; Oldham, S.; Tiego, J.; Paquola, C.; Gerring, Z. F.; Aquino, K. M.; Hawi, Z.; Johnson, B.; Ball, G. M.; Klein, M.; Deco, G.; Franke, B.; Bellgrove, M.; Fornito, A.
10.1101/2020.06.21.163915 — neuroscience — Posted on 2020-06-22
1460 Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin
Dyring-Andersen, B.; Loevendorf, M. B.; Coscia, F.; Santos, A.; Moeller, L. B. P.; Colaco, A. R.; Niu, L.; Bzorek, M.; Doll, S.; Lock Andersen, J.; Clark, R. A.; Skov, L.; Teunissen, M. B. M.; Mann, M.
10.1101/2020.06.22.163717 — cell biology — Posted on 2020-06-22
1462 Bacterial retrons encode tripartite toxin/antitoxin systems
Bobonis, J.; Mateus, A.; Pfalz, B.; Garcia-Santamarina, S.; Galardini, M.; Kobayashi, C.; Stein, F.; Savitski, M. M.; Elfenbein, J. R.; Andrews-Poymenis, H.; Typas, A.
10.1101/2020.06.22.160168 — microbiology — Posted on 2020-06-22
1463 Synergistic epistasis enhances cooperativity of mutualistic interspecies interactions
Turkarslan, S.; Stopnisek, N.; Thompson, A. W.; Arens, C. E.; Valenzuela, J. J.; Wilson, J.; Hunt, K. A.; Hardwicke, J.; Lim, S.; Seah, Y. M.; Fu, Y.; Wu, L.; Zhou, J.; Hillesland, K. L.; Baliga, N. S.; Stahl, D. A.
10.1101/2020.06.22.160184 — evolutionary biology — Posted on 2020-06-22
1468 Phage proteins block and trigger retron toxin/antitoxin systems
Bobonis, J.; Mitosch, K.; Mateus, A.; Kritikos, G.; Elfenbein, J. R.; Savitski, M. M.; Andrews-Polymenis, H.; Typas, A.
10.1101/2020.06.22.160242 — microbiology — Posted on 2020-06-22
1470 Fast Sparse-Group Lasso Method for Multi-response Cox Model with Applications to UK Biobank
Li, R.; Tanigawa, Y.; Justesen, J.; Taylor, J.; Hastie, T.; Tibshirani, R. J.; Rivas, M. A.
10.1101/2020.06.21.163675 — bioinformatics — Posted on 2020-06-22
1471 Naturalistic coding of working memory in primate prefrontal cortex
Roussy, M.; Luna, R.; Duong, L.; Corrigan, B.; Gulli, R. A.; Nogueira, R.; Moreno-Bote, R.; Sachs, A. J.; Palaniyappan, L.; Martinez-Trujillo, J. C.
10.1101/2020.06.19.162446 — neuroscience — Posted on 2020-06-22
1475 Rate volatility and asymmetric segregation diversify mutation burden in mutator cells.
Dowsett, I. T.; Sneeden, J.; Olson, B.; Mckay-Fleisch, J.; McAuley, E.; Kennedy, S. R.; Herr, A. J.
10.1101/2020.06.21.163451 — cancer biology — Posted on 2020-06-22
1477 Vegetative phase change in Populus tremula x alba
Lawrence, E. H.; Leichty, A. R.; Ma, C.; Strauss, S. H.; Poethig, R. S.
10.1101/2020.06.21.163469 — plant biology — Posted on 2020-06-22
1479 Amyloid-beta mediates homeostatic synaptic plasticity
Galanis, C.; Fellenz, M.; Becker, D.; Bold, C.; Lichtenthaler, S. F.; Mueller, U. C.; Deller, T.; Vlachos, A.
10.1101/2020.06.22.152066 — neuroscience — Posted on 2020-06-22
1480 HSC70, HSPA1A, and HSP90AB1 Facilitate Ebola Virus trVLPs to Induce Autophagy
Yu, D.-S.; Yao, S.-H.; Xi, W.-N.; Cheng, L.-F.; Liu, F.-M.; Wu, H.-B.; Lu, X.-Y.; Wu, N.-P.; Sun, S.-L.; Yao, H.-P.
10.1101/2020.06.22.163683 — molecular biology — Posted on 2020-06-22
1481 Bacterial retrons function in anti-phage defense
Millman, A.; Bernheim, A.; Stokar-Avihail, A.; Fedorenko, T.; Voichek, M.; Leavitt, A.; Sorek, R.
10.1101/2020.06.21.156273 — microbiology — Posted on 2020-06-22
1485 Orbitofrontal lesion patients show an implicit approach bias to angry faces
Buades-Rotger, M.; Solbakk, A.-K.; Liebrand, M.; Endestad, T.; Funderud, I.; Siegwardt, P.; Enter, D.; Roelofs, K.; Kraemer, U. M.
10.1101/2020.06.21.162628 — neuroscience — Posted on 2020-06-22
1486 An Age-Specific Atlas for Delineation of White Matter Pathways in Children Aged 6-8 Years
Spencer, A.; Byrne, H.; Lee-Kelland, R.; Jary, S.; Thoresen, M.; Cowan, F.; Chakkarapani, E.; Brooks, J. C. W.
10.1101/2020.06.21.157222 — neuroscience — Posted on 2020-06-22
1488 Statistical Pitfalls in Brain Age Analyses
Butler, E. R.; Chen, A. A.; Ramadan, R.; Ruparel, K.; Moore, T. M.; Zhang, F.; Shou, H.; Gur, R. C.; Nichols, T. E.; Shinohara, R. T.
10.1101/2020.06.21.163741 — neuroscience — Posted on 2020-06-22
1492 Robust gene coexpression networks using signed distance correlation
Pardo-Diaz, J.; Bozhilova, L. V.; Beguerisse-Diaz, M.; Poole, P. S.; Deane, C. M.; Reinert, G.
10.1101/2020.06.21.163543 — bioinformatics — Posted on 2020-06-22
1495 Mapping cell structure across scales by fusing protein images and interactions
Qin, Y.; Winsnes, C. F.; Huttlin, E. L.; Zheng, F.; Ouyang, W.; Park, J.; Pitea, A.; Kreisberg, J. F.; Gygi, S. P.; Harper, J. W.; Ma, J.; Lundberg, E.; Ideker, T.
10.1101/2020.06.21.163709 — systems biology — Posted on 2020-06-22
1496 Pangenome of white lupin provides insights into the diversity of the species
Hufnagel, B.; Soriano, A.; Taylor, J.; Divol, F.; Kroc, M.; Sanders, H.; Yeheyis, L.; Nelson, M.; Peret, B.
10.1101/2020.06.21.163378 — plant biology — Posted on 2020-06-22
1498 LATER but FORTIOR: diffusion modelling of inhibition of return
Seidel Malkinson, T.; Bourgeois, A.; Wattiez, N.; Pouget, P.; Bartolomeo, P.
10.1101/2020.06.21.163485 — neuroscience — Posted on 2020-06-22
1499 ASpli2: Integrative analysis of splicing landscapesthrough RNA-Seq assays
Mancini, E.; Rabinovich, A.; Iserte, J.; Yanovsky, M.; Chernomoretz, A.
10.1101/2020.06.21.162891 — bioinformatics — Posted on 2020-06-22
1500 Selective REM-Sleep Suppression Increases Next-Day Negative Affect and Amygdala Responses to Social Exclusion
Glosemeyer, R. W.; Diekelmann, S.; Cassel, W.; Koehler, U.; Kesper, K.; Westermann, S.; Steffen, A.; Borgwardt, S.; Wilhelm, I.; Mueller-Pinzler, L.; Paulus, F. M.; Krach, S.; Stolz, D. S.
10.1101/2020.06.15.148759 — neuroscience — Posted on 2020-06-21
1501 Single cell sequencing of the small and AT-skewed genome of malaria parasites
Liu, S.; Huckaby, A. C.; Brown, A. C.; Moore, C. C.; Burbulis, I. E.; McConnell, M. J.; Guler, J. L.
10.1101/2020.02.21.960039 — genomics — Posted on 2020-06-21
1502 Quantification of DNA methylation using methylation-sensitive restriction enzymes and multiplex digital PCR
Nell, R. J.; van Steenderen, D.; Menger, N. V.; Weitering, T. J.; Versluis, M.; van der Velden, P. A.
10.1101/816744 — genomics — Posted on 2020-06-21
1507 Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and circadian rhythms.
Saner, N. J.; Lee, M. J.-C.; Kuang, J.; Pitchford, N. W.; Roach, G. D.; Garnham, A.; Genders, A. J.; Stokes, T.; Schroder, E. A.; Esser, K. A.; Phillips, S. M.; Bishop, D. J.; Bartlett, J. D.
10.1101/2020.06.21.163733 — physiology — Posted on 2020-06-21
1508 Non-canonical immune response to the inhibition of DNA methylation via stabilization of endogenous retrovirus dsRNAs
Ku, Y.; Park, J.-H.; Cho, R.; Lee, Y.; Park, H.-M.; Kim, M.; Hur, K.; Byun, S. Y.; Liu, J.; Shum, D.; Shin, D.-Y.; Koh, Y.; Cho, J.-Y.; Yoon, S.-S.; Hong, J.; Kim, Y.
10.1101/2020.06.21.163857 — molecular biology — Posted on 2020-06-21
1510 Arsenic trioxide resistance in acute promyelocytic leukemia: More to it than PML mutations
Balasundaram, N.; Ganesan, S.; Chendamarai, E.; Palani, H. K.; Venkatraman, A.; Alex, A. A.; David, S.; Krishna, S.; Korula, A.; Janet, N. B.; Balasubramanian, P.; Mathews, V.
10.1101/2020.06.21.154633 — cancer biology — Posted on 2020-06-21
1511 Absence of heme at the catalytic site of heme oxygenase-2 triggers its lysosomal degradation
Liu, L.; Dumbrepatil, A. B.; Fleischhacker, A. S.; Marsh, E. N. G.; Ragsdale, S. W.
10.1101/2020.06.21.163881 — biochemistry — Posted on 2020-06-21
1512 Competitive mapping allows to identify and exclude human DNA contamination in ancient faunal genomic datasets
Feuerborn, T. R.; Palkopoulou, E.; van der Valk, T.; von Seth, J.; Munters, A.; Pecnerova, P.; Dehasque, M.; Urena, I.; Ersmark, E.; Lagerholm, V. K.; Krzewinska, M.; Rodriguez-Varela, R.; Götherström, A.; Dalen, L.; Diez-del-Molino, D.
10.1101/2020.03.05.974907 — genomics — Posted on 2020-06-21
1514 Dihydroxyacetone phosphate signals glucose availability to mTORC1
Orozco, J. M.; Krawczyk, P. A.; Scaria, S. M.; Cangelosi, A. L.; Chan, S. H.; Kunchok, T.; Lewis, C. A.; Sabatini, D.
10.1101/2020.06.21.161927 — cell biology — Posted on 2020-06-21
1517 CliqueSNV: An Efficient Noise Reduction Technique for Accurate Assembly of ViralVariants from NGS Data
Knyazev, S.; Tsyvina, V.; Melnyk, A.; Artyomenko, A.; Malygina, T.; Porozov, Y. B.; Campbell, E.; Switzer, W. M.; Skums, P.; Zelikovsky, A.
10.1101/264242 — bioinformatics — Posted on 2020-06-21
1521 Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection
STRESSMANN, F. A.; BERNAL-BAYARD, J.; PEREZ-PASCUAL, D.; AUDRAIN, B.; RENDUELES, O.; BRIOLAT, V.; BRUCHMANN, S.; VOLANT, S.; GHOZLANE, A.; HAUSSLER, S.; DUCHAUD, E.; LEVRAUD, J.-P.; GHIGO, J.-M.
10.1101/2020.04.23.058222 — microbiology — Posted on 2020-06-21
1522 Characterization of 100 sequential SARS-CoV-2 convalescent plasma donations
Jungbauer, C.; Weseslindtner, L.; Weidner, L.; Gaensdorfer, S.; Farcet, M. R.; Gschaider-Reichhart, E.; Kreil, T. R.
10.1101/2020.06.21.163444 — immunology — Posted on 2020-06-21
1523 ADA2 is a lysosomal DNase regulating the type-I interferon response
Baash, S.; Bartok, E.; Boehler, V.; Ebersbach, H.; Geiger, R.; Greiner-Tollersrud, O. K.; Grimbacher, B.; Guerini, D.; Hartmann, G.; Huebscher, K.; Kochs, G.; Krausz, M.; Marchant, M.; Polyzou, A.; Schepp, J.; Seidl, M.; Smulski, C. R.; Staab, D.; Trompouki, E.; Warncke, M.; Olsen, J. O.; Link, R.; Srinivas, H.; Henneke, P.; Raieli, S.; Proietti, M.
10.1101/2020.06.21.162990 — immunology — Posted on 2020-06-21
1524 Plasmids shape the diverse accessory resistomes of Escherichia coli ST131
Decano, A. G.; Tran, N.; Al-Foori, H.; Al-Awadi, B.; Leigh Campbell, L.; Ellison, K.; Mirabueno, L. P.; Nelson, M.; Power, S.; Smith, G.; Smyth, C.; Vance, Z.; Rahm, A.; Downing, T.
10.1101/2020.05.07.081380 — genomics — Posted on 2020-06-21
1526 Assessing the effects of thinning on stem growth allocation of individual Scots pine trees
Saarinen, N.; Kankare, V.; Yrttimaa, T.; Viljanen, N.; Honkavaara, E.; Holopainen, M.; Hyyppa, J.; Huuskonen, S.; Hynynen, J.; Vastaranta, M.
10.1101/2020.03.02.972521 — ecology — Posted on 2020-06-21
1527 Single cell reconstruction of human basal cell diversity in normal and IPF lung.
Carraro, G.; Mulay, A.; Yao, C.; Mizuno, T.; Konda, B.; Petrov, M.; Lafkas, D.; Arron, J. R.; Hogaboam, C. M.; Chen, P.; Jiang, D.; Noble, P.; Randell, S. H.; McQualter, J. L.; Stripp, B.
10.1101/2020.06.19.162305 — cell biology — Posted on 2020-06-21
1529 Inflammatory state of lymphatic vessels and miRNA profiles associated with relapse in ovarian cancer patients
Johnson, S. C.; Chakraborty, S.; Drosou, A.; Cunnea, P.; Tzovaras, D.; Nixon, K.; Zawieja, D. C.; Muthuchamy, M.; Fotopoulou, C.; Moore, J. E.
10.1101/2020.02.24.962480 — cancer biology — Posted on 2020-06-21
1531 Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues
Varner, E. L.; Trefely, S.; Bartee, D.; von Krusenstiern, E.; Izzo, L.; Bekeova, C.; O'Connor, R. S.; Seifert, E. L.; Wellen, K.; Meier, J. L.; Snyder, N. W.
10.1101/2020.03.15.992859 — biochemistry — Posted on 2020-06-21
1532 Detecting sample swaps in diverse NGS data types using linkage disequilibrium
Javed, N. M.; Farjoun, Y.; Fennell, T. J.; Epstein, C. B.; Bernstein, B. E.; Shoresh, N.
10.1101/2020.03.15.992750 — bioinformatics — Posted on 2020-06-21
1533 Structural modeling and thermostability of a serine protease inhibitor belonging to the Kunitz family from the tick Rhipicephalus microplus
Bomediano-Camillo, L. d. M.; Ferreira, G. C.; Duran, A. F. A.; da Silva, F. R. S.; Garcia, W.; Scott, A. L.; Sasaki, S. D.
10.1101/2020.06.20.163246 — biochemistry — Posted on 2020-06-21
1534 Reliability, sensitivity and predictive value of fMRI during multiple object tracking as a marker of cognitive training in stroke survivors.
Kolskaar, K. K.; Richard, G.; Alnaes, D.; Dorum, E. S.; Sanders, A.-M.; Ulrichsen, K. M.; Monereo Sanchez, J.; Ihle-Hansen, H.; Nordvik, J. E.; Westlye, L. T.
10.1101/603985 — neuroscience — Posted on 2020-06-21
1535 Chimpanzee Brain Morphometry Utilizing Standardized MRI Preprocessing and Macroanatomical Annotations
Vickery, S.; Hopkins, W. D.; Sherwood, C. C.; Schapiro, S. J.; Latzman, R. D.; Caspers, S.; Gaser, C.; Eickhoff, S. B.; Dahnke, R.; Hoffstaedter, F.
10.1101/2020.04.20.046680 — neuroscience — Posted on 2020-06-21
1538 A Genetically Encoded and Versatile Probe for Fluorescence Polarization Detection
Sugizaki, A.; Sato, K.; Chiba, K.; Saito, K.; Kawagishi, M.; Tomabechi, Y.; Mehta, S. B.; Ishii, H.; Sakai, N.; Shirouzu, M.; Tani, T.; Terada, S.
10.1101/2020.06.20.116178 — cell biology — Posted on 2020-06-21
1542 Deformed Wing Virus spillover from honey bees to bumble bees: a reverse genetic study.
Gusachenko, O. N.; Woodford, L.; Balbirnie-Cumming, K.; Ryabov, E. V.; Evans, D. J.
10.1101/2019.12.18.880559 — microbiology — Posted on 2020-06-21
1543 Community structure of phototrophic co-cultures from extreme environments
Shaw, C.; Brooke, C. G.; Connolly, M. P.; Garcia, J. A.; Harmon-Smith, M.; Shapiro, N.; Hawley, E.; Barton, M.; Tringe, S. G.; Glavina del Rio, T.; Culley, D. E.; Castenholtz, R.; Hess, M.
10.1101/427211 — microbiology — Posted on 2020-06-21
1545 U2AF1 is a haplo-essential gene required for cancer cell survival
Wadugu, B. A.; Heard, A.; Srivatsan, S. N.; Alberti, M. O.; Ndonwi, M.; Bradley, J.; Shao, J.; Ahmed, T.; Shirai, C. L.; Khanna, A.; Fei, D. L.; Miller, C. A.; Graubert, T. A.; Walter, M. J.
10.1101/2020.06.20.151035 — cancer biology — Posted on 2020-06-21
1546 Neurotrophic Factor-Laden Acellular Chondroitin Sulfate Scaffolds Promote Chronic Functional Recovery After Severe Traumatic Brain Injury
Latchoumane, C.-F. V.; Betancur, M. I.; Simchick, G.; Sun, M. K.; Forghani, R.; Lenear, C.; Ahmed, A.; Mohankumar, R.; Balaji, N.; Mason, H. D.; Holmes, P. V.; Zhao, Q.; Bellamkonda, R.; Karumbaiah, L.
10.1101/2020.06.21.116970 — bioengineering — Posted on 2020-06-21
1550 Iron limitation by transferrin promotes simultaneous cheating of pyoverdine and exoprotease in Pseudomonas aeruginosa
Tostado-Islas, O.; Mendoza-Ortiz, A.; Ramirez-Garcia, G.; Cabrera-Takane, I. D.; Loarca, D.; Perez-Gonzalez, C.; Jasso-Chavez, R.; Jimenez-Cortes, J. G.; Hoshiko, Y.; Maeda, T.; Cazares, A.; Garcia-Contreras, R.
10.1101/2020.06.21.163022 — microbiology — Posted on 2020-06-21
1554 Development of zygotic and germline gene drives in mice
Pfitzner, C.; Hughes, J. N.; White, M. A.; Scherer, M.; Piltz, S. G.; Thomas, P. Q.
10.1101/2020.06.21.162594 — genetics — Posted on 2020-06-21
1555 Exploring Chromosomal Structural Heterogeneity AcrossMultiple Cell Lines
Cheng, R. R.; Contessoto, V.; Aiden, E. L.; Wolynes, P. G.; Di Pierro, M.; Onuchic, J. N.
10.1101/2020.03.21.001917 — biophysics — Posted on 2020-06-21
1557 Aberrant regulation of a poison exon caused by a non-coding variant in Scn1a-associated epileptic encephalopathy
Voskobiynyk, Y.; Battu, G.; Felker, S. A.; Cochran, J. N.; Newton, M. P.; Lambert, L. J.; Kesterson, R. A.; Myers, R. M.; Cooper, G. M.; Roberson, E. D.; Barsh, G.
10.1101/2020.06.21.163428 — genetics — Posted on 2020-06-21
1558 A quantitative principle to understand 3D cellular connectivity in epithelial tubes
Gomez-Galvez, P.; Vicente-Munuera, P.; Anbari, S.; Tagua, A.; Gordillo, C.; Palacios, A. M.; Velasco, A.; Capitan-Agudo, C.; Grima, C.; Annese, V.; Robles, R.; Marquez, A.; Buceta, J.; Escudero, L. M.
10.1101/2020.02.19.955567 — developmental biology — Posted on 2020-06-21
1561 Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins
Singh, N.; Reyes-Ordonez, A.; Compagnone, M. A.; Moreno Castillo, J. F.; Leslie, B. J.; Ha, T.; Chen, J.
10.1101/2020.06.20.163253 — biochemistry — Posted on 2020-06-21
1563 Functional Role of Second Heart Field-derived Smooth Muscle Cells in Thoracic Aortopathies in Mice
Sawada, H.; Higashi, H.; Zhang, C.; Li, Y.; Katsumata, Y.; Morgan, S.; Lee, L. H.; Singh, S. A.; Chen, J. Z.; Moorleghen, J. J.; Howatt, D. A.; Rateri, D. L.; Lu, H. S.; Shen, Y. H.; LeMaire, S. A.; Aikawa, M.; Majesky, M. W.; Daugherty, A.
10.1101/2020.02.02.930917 — pathology — Posted on 2020-06-21
1564 Motor imagery practice during arm-immobilization benefits sensorimotor cortical functions and plasticity-related sleep features
Debarnot, U.; Perrault, A. A.; Sterpenich, V. A.; Legendre, G.; Huber, C.; Guillot, A.; Schwartz, S.
10.1101/828889 — neuroscience — Posted on 2020-06-21
1566 Metagenomic survey unravels diversities of biogas' microbiomes with potential to enhance its' productivity in Kenya
Muturi, S. M.; Muthui, L. W.; Njogu, P. M.; Onguso, J. M.; Wachira, F. N.; Opiyo, S. O.; Pelle, R.
10.1101/2020.04.23.048504 — microbiology — Posted on 2020-06-21
1567 Evidence of natural selection in human complex phenotypes from GWAS summary statistics
Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.
10.1101/705285 — genomics — Posted on 2020-06-21
1568 Joint single cell DNA-Seq and RNA-Seq of gastric cancer reveals subclonal signatures of genomic instability and gene expression
Andor, N.; Lau, B. T.; Catalanotti, C.; Kumar, V.; Sathe, A.; Belhocine, K.; Wheeler, T. D.; Price, A. D.; Song, M.; Dzakula, Z.; Sorenson, J.; Stafford, D.; Bent, Z.; DeMare, L.; Hepler, L.; Jett, S.; Lin, B. K.; Maheshwari, S.; Makarewicz, A. J.; Rahimi, M.; Sawhney, S. S.; Sauzade, M.; Shuga, J.; Sullivan-Bibee, K.; Weinstein, A.; Yang, W.; Yin, Y.; Kubit, M. A.; Chen, J.; Grimes, S. M.; Suarez, C. J.; Poultsides, G. A.; Schnall-Levin, M.; Bharadwaj, R.; Ji, H. P.
10.1101/445932 — genomics — Posted on 2020-06-21
1569 ADAR1 can drive Multiple Myeloma progression by acting both as an RNA editor of specific transcripts and as a DNA mutator of their cognate genes
Tasakis, R. N.; Lagana, A.; Stamkopoulou, D.; Melnekoff, D. T.; Nedumaran, P.; Leshchenko, V.; Pecori, R.; Parekh, S.; Papavasiliou, F. N.
10.1101/2020.02.11.943845 — genomics — Posted on 2020-06-21
1571 A statistical framework for assessing pharmacological response and biomarkers using uncertainty estimates
Wang, D.; Hensman, J.; Kutkaite, G.; Toh, T. S.; GDSC Screening Team, ; Dry, J. R.; Saez-Rodriguez, J.; Garnett, M.; Menden, M. P.; Dondelinger, F.
10.1101/2020.05.01.072983 — cancer biology — Posted on 2020-06-21
1575 ERR agonism reverses mitochondrial dysfunction and inflammation in the aging kidney
Wang, X. X.; Myakala, K.; Libby, A. E.; Ranjit, S.; Takahashi, S.; Jones, B. A.; Bhasin, K.; Qi, Y.; Krausz, K.; Zerfas, P.; Panov, J.; velenosi, t. J.; patel, d. P.; Daneshpajouhnejad, P.; Titievsky, A.; Sharov, V.; Ostretsov, B.; Billon, C.; Kopp, J. B.; Rosenberg, A. Z.; Gonzalez, F. J.; Guha, U.; Brodsky, L.; Burris, T.; Levi, M.
10.1101/755801 — pathology — Posted on 2020-06-21
1576 Functional reconstitution of a bacterial CO2 concentrating mechanism in E. coli
Flamholz, A. I.; Dugan, E.; Blikstad, C.; Gleizer, S.; Ben-Nissan, R.; Amram, S.; Antonovsky, N.; Ravishankar, S.; Noor, E.; Bar-Even, A.; Milo, R.; Savage, D.
10.1101/2020.05.27.119784 — microbiology — Posted on 2020-06-21
1577 Analysis of Gene Expression from Systemic Lupus Erythematosus Synovium Reveals a Profile of Activated Immune Cells and Inflammatory Pathways
Hubbard, E. L.; Catalina, M. D.; Heuer, S.; Bachali, P.; Robl, R. D.; Geraci, N. S.; Grammer, A. C.; Lipsky, P. E.
10.1101/2020.06.19.123307 — immunology — Posted on 2020-06-21
1581 A path towards SARS-CoV-2 attenuation: metabolic pressure on CTP synthesis rules the virus evolution
Ou, Z.; Ouzounis, C.; Wang, D.; Sun, W.; Li, J.; Chen, W.; Marliere, P.; Danchin, A.
10.1101/2020.06.20.162933 — genomics — Posted on 2020-06-21
1582 Genomic diversity and hotspot mutations in 30,983 SARS-CoV-2 genomes: moving toward a universal vaccine for the "confined virus"?
Alouane, T.; Laamarti, M.; Essabbar, A.; Hakmi, M.; Bouricha, E. M.; Chemao-Elfihri, M. W.; Kartti, S.; Boumajdi, N.; Bendani, H.; Laamarti, R.; Ghrifi, F.; Allam, L.; Aanniz, T.; Ouadghiri, M.; El Hafidi, N.; El Jaoudi, R.; Benrahma, H.; El Attar, J.; Mentag, R.; Sbabou, L.; Nejjari, C.; Amzazi, S.; Belyamani, L.; Ibrahimi, A.
10.1101/2020.06.20.163188 — genomics — Posted on 2020-06-21
1584 SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and prolonged shedding of infectious virus from both respiratory and gastrointestinal tracts
Hartman, A. L.; Nambulli, S.; McMillen, C. M.; White, A. G.; Tilston-Lunel, N.; Albe, J. R.; Cottle, E. L.; Dunn, M. D.; Frye, L. J.; Gilliland, T. H.; Olsen, E. L.; O'Malley, K. J.; Schwarz, M. M.; Tomko, J. A.; Walker, R. C.; Xia, M.; Hartman, M. S.; Klein, E.; Scanga, C.; Flynn, J. L.; Klimstra, W. B.; McElroy, A. K.; Reed, D. S.; Duprex, W. P.
10.1101/2020.06.20.137687 — microbiology — Posted on 2020-06-21
1588 Controlling protein nanocage assembly with hydrostatic pressure
Le Vay, K. K.; Carter, B. M.; Watkins, D. W.; Tang, T.-Y. D.; Ting, V. P.; Cölfen, H.; Rambo, R. P.; Smith, A. J.; Anderson, J. L. R.; Perriman, A. W.
10.1101/2020.06.16.154534 — biophysics — Posted on 2020-06-21
1589 Modulation of root growth by nutrient-defined fine-tuning of polar auxin transport
Otvos, K.; Marconi, M.; Vega, A.; O'Brien, J.; Johnson, A.; Abualia, R.; Antonielli, L.; Montesinos, J. C.; Zhang, Y.; Tan, S.-T.; Cuesta, C.; Artner, C.; Bouguyon, E.; Gojon, A.; Friml, J.; Gutierrez, R. A.; Wabnik, K.; Benkova, E.
10.1101/2020.06.19.160994 — plant biology — Posted on 2020-06-21
1592 The instantaneous multi-pronged defense system of latex against general plant enemies
Salome-Abarca, L. F.; Gođevac, D.; Kim, M. S.; Hwang, G.-S.; Park, S. C.; Jang, Y. P.; van den Hondel, C. A. M. J. J.; Verpoorte, R.; Klinkhamer, P.; Choi, Y. H.
10.1101/2020.06.19.161869 — ecology — Posted on 2020-06-21
1593 Xyloglucan remodelling defines differential tissue expansion in plants
Velasquez, S. M.; Guo, X.; Gallemi, M.; Aryal, B.; Venhuizen, P.; Barbez, E.; Dünser, K.; Darino, M.; Pencik, A.; Novak, O.; Kalyna, M.; Mouille, G.; Benkova, E.; Bhalerao, R.; Mravec, J.; Kleine-Vehn, J.
10.1101/808964 — plant biology — Posted on 2020-06-21
1594 Low competitive status elicits aggression: behavioral and neural evidence
Buades-Rotger, M.; Goettlich, M.; Weiblen, R.; Petereit, P.; Scheidt, T.; Keevil, B. G.; Kraemer, U. M.
10.1101/2020.06.20.162586 — neuroscience — Posted on 2020-06-21
1595 Principles for coding associative memories in a compact neural network
Pritz, C.; Itskovits, E.; Bokman, E.; Ruach, R.; Gritsenko, V.; Nelken, T.; Menasherof, M.; Azulay, A.; Zaslaver, A.
10.1101/2020.06.20.162818 — neuroscience — Posted on 2020-06-21
1597 The Impact of the Siemens Trio to Prisma Upgrade and Volumetric Navigators on MRI Indices: A Reliability Study with Implications for Longitudinal Study Designs
Plitman, E.; Bussy, A.; Valiquette, V.; Salaciak, A.; Patel, R.; Beland, M.-L.; Tullo, S.; Tardif, C.; Rajah, M. N.; Near, J.; Devenyi, G. A.; Chakravarty, M. M.
10.1101/2020.06.19.162420 — neuroscience — Posted on 2020-06-20
1600 Immune responses in pancreatic cancer may be restricted byprevalence of activated regulatory T-cells, dysfunctionalCD8+ T-cells, and senescent T-cells
Sivakumar, S.; Abu-Shah, E.; Ahern, D.; Arbe-Barnes, E. H.; Mangal, N.; Reddy, S.; Rendek, A.; Easton, A.; Kurz, E.; Silva, M.; Heij, L. R.; Soonawalla, Z.; Bashford-Rogers, R.; Middleton, M. R.; Dustin, M.
10.1101/2020.06.20.163071 — immunology — Posted on 2020-06-20
1604 Identification of Retinal Ganglion Cell Types and Brain Nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.
Parmhans, N.; Fuller, A. D.; Nguyen, E.; Chuang, K.; Swygart, D. I.; Wienbar, S. R.; Lin, T.; Kozmik, Z.; Dong, L.; Schwartz, G. W.; Badea, T. C.
10.1101/2020.06.20.162859 — neuroscience — Posted on 2020-06-20
1606 A combined characterization of coelomic fluid cell types in the spiny starfish Marthasterias glacialis: inputs from flow cytometry and imaging
Oliveira, B.; guatelli, s.; Martinez, P.; Simoes, B.; Bispo, C.; Andrade, C.; Ferrario, C.; Bonasoro, F.; Rino, J.; Sugni, M.; Gardner, R.; Zilhao, R.; Coelho, A. V.
10.1101/2020.06.20.163196 — cell biology — Posted on 2020-06-20
1607 An implant for long-term cervical vagus nerve stimulation in mice
Mughrabi, I. T.; Hickman, J.; Jayaprakash, N.; Papadoyannis, E. S.; Abbas, A.; Chang, Y.-C.; Lee, S.; Datta-Chaudhuri, T.; Chang, E. H.; Zanos, T. P.; Froemke, R. C.; Welle, C.; Al-Abed, Y.; Zanos, S.
10.1101/2020.06.20.160473 — bioengineering — Posted on 2020-06-20
1608 Sequential Activation of Guide RNAs for Algorithmic Multiplexing of Cas9 Activities
Clarke, R.; Terry, A. R.; Pennington, H. M.; Macdougall, M. S.; Regan, M.; Merrill, B.
10.1101/2020.06.20.162982 — synthetic biology — Posted on 2020-06-20
1613 High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases
Koyama-Honda, I.; Fujiwara, T. K.; Kasai, R. S.; Suzuki, K. G. N.; Kajikawa, E.; Tsuboi, H.; Tsunoyama, T. A.; Kusumi, A.
10.1101/2020.06.20.162545 — cell biology — Posted on 2020-06-20
1615 Crystal structures of peanut lectin in the presence of synthetic β-N- and β-S-galactosidesdisclose evidences for the recognition of different glycomimetic ligands
Cagnoni, A. J.; Primo, E. D.; Klinke, S.; Cano, M. E.; Giordano, W.; Marino, K. V.; Kovensky, J.; Goldbaum, F. A.; Uhrig, M. L.; Otero, L. H.
10.1101/2020.06.20.162875 — biochemistry — Posted on 2020-06-20
1616 Multi-Omics and Integrated Network Approach to Unveil Evolutionary Patterns, Mutational Hotspots, Functional Crosstalk and Regulatory Interactions in SARS-CoV-2
Gupta, V.; Haider, S.; Verma, M.; Ponnusamy, K.; Malik, M. Z.; Singhvi, N.; Verma, H.; Kumar, R.; Sood, U.; Hira, P.; Satija, S.; Lal, R.
10.1101/2020.06.20.162560 — microbiology — Posted on 2020-06-20
1621 UNC-45A Destabilizes MTs Independent of its Effect on Non-Muscle Myosin II
Bazzaro, M.; Habicht, J.; Mooneyham, A.; Shetty, M.; Zhang, X.; Emmings, E.; Yang, Q.; Coombes, C.; Gardner, M. K.
10.1101/2020.06.20.163048 — cell biology — Posted on 2020-06-20
1632 Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity
Babolmorad, G.; Latif, A.; Pollock, N. M.; Domingo, I. K.; Delyea, C.; Rieger, A. M.; Allison, W. T.; Bhavsar, A. P.
10.1101/2020.06.19.162057 — pharmacology and toxicology — Posted on 2020-06-20
1634 Gnotobiotic rainbow trout (Oncorhynchus mykiss) model reveals endogenous bacteria that protect against Flavobacterium columnare infection
PEREZ-PASCUAL, D.; VENDRELL-FERNANDEZ, S.; AUDRAIN, B.; BERNAL-BAYARD, J.; PATINO-NAVARRETE, R.; PETIT, V.; RIGAUDEAU, D.; GHIGO, J.-M.
10.1101/2020.06.19.161471 — microbiology — Posted on 2020-06-20
1635 Repeatability and reproducibility of the wzi High Resolution Melting-based clustering analysis for Klebsiella pneumoniae typing
Pasala, A. R.; Perini, M.; Piazza, A.; Di Carlo, D.; Loretelli, C.; Cafiso, A.; Inglese, S.; Zuccotti, G. V.; Comandatore, F.
10.1101/2020.06.19.161703 — microbiology — Posted on 2020-06-20
1636 SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients
Klimstra, W. B.; Tilston-Lunel, N. L.; Nambulli, S.; Boslett, J.; McMillen, C. M.; Gilliland, T.; Dunn, M. D.; Sun, C.; Wheeler, S. E.; Wells, A.; Hartman, A. L.; McElroy, A. K.; Reed, D. S.; Rennick, L. J.; Duprex, W. P.
10.1101/2020.06.19.154930 — microbiology — Posted on 2020-06-20
1637 Rapid Inactivation of SARS-CoV-2 by Silicon Nitride, Copper, and Aluminum Nitride
Pezzotti, G.; Ohgitani, E.; Shin-Ya, M.; Adachi, T.; Marin, E.; Boschetto, F.; Zhu, W.; Mazda, O.
10.1101/2020.06.19.159970 — microbiology — Posted on 2020-06-20
1638 Structural variability, expression profile and pharmacogenetics properties of TMPRSS2 gene as a potential target for COVID-19 therapy
Zarubin, A.; Stepanov, V.; Markov, A.; Kolesnikov, N.; Marusin, A.; Khitrinskaya, I.; Swarovskaya, M.; Litvinov, S.; Ekomasova, N.; Dzhaubermezov, M.; Maksimova, N.; Sukhomyasova, A.; Shtygasheva, O.; Khusnutdinova, E.; Radjabov, M.; Kharkov, V.
10.1101/2020.06.20.156224 — genomics — Posted on 2020-06-20
1642 The D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity and decreases neutralization sensitivity to individual convalescent sera
Hu, J.; He, C. L.; Gao, Q.; Zhang, G. J.; Cao, X. X.; Long, Q. X.; Deng, H. J.; Huang, L. Y.; Chen, J.; Wang, K.; Tang, N.; Huang, A. L.
10.1101/2020.06.20.161323 — microbiology — Posted on 2020-06-20
1644 Identification of sex differences in tumor-specific T cell infiltration in bladder tumor-bearing mice treated with BCG immunotherapy
Rousseau, M.; O'Brien, C. J. O.; Antequera, E.; Zdimerova, H.; Cansever, D.; Canton, T.; Zychlinsky Scharff, A.; Ingersoll, M. A.
10.1101/2020.06.19.161554 — immunology — Posted on 2020-06-20
1645 Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19
Graham, S. P.; McLean, R. K.; Spencer, A. J.; Belij-Rammerstorfer, S.; Wright, D.; Ulaszewska, M.; Edwards, J. C.; Hayes, J. W. P.; Martini, V.; Thakur, N.; Conceicao, C.; Dietrich, I.; Shelton, H.; Waters, R.; Ludi, A.; Wilsden, G.; Browning, C.; Bialy, D.; Bhat, S.; Stevenson-Leggett, P.; Hollinghurst, P.; Gilbride, C.; Pulido, D.; Moffat, K.; Sharpe, H.; Allen, E.; Mioulet, V.; Chiu, C.; Newman, J.; Asfor, A. S.; Burman, A.; Crossley, S.; Huo, J.; Owens, R. J.; Carroll, M.; Hammond, J. A.; Tchilian, E.; Bailey, D.; Charleston, B.; Gilbert, S. C.; Tuthill, T. J.; Lambe, T.
10.1101/2020.06.20.159715 — immunology — Posted on 2020-06-20
1646 Computationally efficient whole genome regression for quantitative and binary traits
Mbatchou, J.; Barnard, L.; Backman, J.; Marcketta, A.; Kosmicki, J. A.; Ziyatdinov, A.; Benner, C.; O'Dushlaine, C.; Barber, M.; Boutkov, B.; Habegger, L.; Ferreira, M.; Reid, J. G.; Abecasis, G.; Maxwell, E.; Marchini, J.
10.1101/2020.06.19.162354 — genetics — Posted on 2020-06-20
1648 Contribution of different host plants to the adult population of western bean cutworm
Bunn, D. C.; Dias de Oliveira, E.; Springborn, F.; Gonzalez-Meler, M. A.; Miller, N. J.
10.1101/2020.06.19.162016 — ecology — Posted on 2020-06-20
1655 Tamoxifen reduces inflammatory infiltration of neutrophils in the airways.
Mansilla, A.; Soto, J.; Henriquez, C.; Philp, A. R.; Mall, M. A.; Sarmiento, J.; Flores, C. A.
10.1101/2020.06.19.161919 — pharmacology and toxicology — Posted on 2020-06-20
1657 QTL mapping for aggressiveness variation in F. graminearum revealed one causal mutation in FgVe1 velvet protein
Laurent, B.; Moinard, M.; Spataro, C.; Chereau, S.; Zehraoui, E.; Blanc, R.; Lasserre-Zuber, P.; Ponts, N.; Foulongne-Oriol, M.
10.1101/2020.06.19.161349 — microbiology — Posted on 2020-06-20
1660 Strongyle-resistant sheep express their potential across environments and leave limited scope for parasite plasticity
Salle, G.; Deiss, V.; Marquis, C.; Tosser-Klopp, G.; Cortet, J.; Serreau, D.; Koch, C.; Marcon, D.; Bouvier, F.; Jacquiet, P.; Holroyd, N.; Blanchard, A.; Cotton, J.; Mialon, M.-M.; Moreno-Romieux, C.
10.1101/2020.06.19.161729 — evolutionary biology — Posted on 2020-06-20
1662 Exposure duration modulates the response of Caribbean corals to global change stressors
Aichelman, H. E.; Bove, C. B.; Castillo, K. D.; Boulton, J. M.; Knowlton, A. C.; Nieves, O. C.; Ries, J. B.; Davies, S. W.
10.1101/2020.06.19.161711 — ecology — Posted on 2020-06-20
1666 Discovery of protein modifications using high resolution differential mass spectrometry proteomics
Cifani, P.; Li, Z.; Luo, D.; Grivainis, M.; Intlekofer, A. M.; Fenyo, D.; Kentsis, A.
10.1101/2020.06.19.162321 — biochemistry — Posted on 2020-06-20
1668 Characterization of the dynamic resting state of a pentameric ligand-gated ion channel by cryo-electron microscopy and simulations
Rovsnik, U.; Zhuang, Y.; Axelsson, L.; Forsberg, B. O.; Lim, V. T.; Carroni, M.; Blau, C.; Howard, R. J.; Lindahl, E.
10.1101/2020.06.19.161356 — biophysics — Posted on 2020-06-20
1672 A novel gonorrhea vaccine composed of MetQ lipoprotein formulated with CpG shortens experimental murine infection
Sikora, A. E.; Gomez, C.; Le Van, A.; Baarda, B. I.; Darnell, s.; Martinez, F. G.; Zielke, R. A.; Bonventre, J. A.; Jerse, A. E.
10.1101/2020.06.19.161646 — microbiology — Posted on 2020-06-20
1674 Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions
Flint, D. B.; Bright, S. J.; McFadden, C. H.; Konishi, T.; Ohsawa, D.; Turner, B. X.; Lin, S. H.; Grosshans, D. R.; Shaitelman, S. F.; Chiu, H.-S.; Sumazin, P.; Sawakuchi, G. O.
10.1101/2020.06.19.161497 — biophysics — Posted on 2020-06-20
1675 A mutation in the Drosophila melanogaster eve stripe 2 minimal enhancer is buffered by flanking sequences
Lopez-Rivera, F.; Foster, O. K.; Vincent, B. J.; Pym, E. C. G.; Bragdon, M. D. J.; Estrada, J.; DePace, A. H.; Wunderlich, Z.
10.1101/2020.06.19.162164 — genetics — Posted on 2020-06-20
1676 Lineage recording reveals dynamics of cerebral organoid regionalization
He, Z.; Gerber, T.; Maynard, A.; Jain, A.; Petri, R.; Santel, M.; Ly, K.; Sidow, L.; Sanchis Calleja, F.; Riesenberg, S.; Camp, J. G.; Treutlein, B.
10.1101/2020.06.19.162032 — developmental biology — Posted on 2020-06-20
1678 Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity.
Inesta-Vaquera, F.; Navasumrit, P.; Henderson, C. J.; Frangova, T. G.; Honda, T.; Dinkova-Kostova, A. T.; Ruchirawat, M.; Wolf, C. R.
10.1101/2020.06.19.161117 — pharmacology and toxicology — Posted on 2020-06-20
1681 CRYO-EM STRUCTURE OF THE DELTA-RETROVIRAL INTASOME IN COMPLEX WITH THE PP2A REGULATORY SUBUNIT B56gamma
Barski, M. S.; Minnell, J. J.; Hodakova, Z.; Pye, V.; Nans, A.; Cherepanov, P.; Maertens, G. N.
10.1101/2020.06.19.161513 — biochemistry — Posted on 2020-06-20
1682 Genome-wide association study in European patients with congenital heart disease identifies risk loci for transposition of the great arteries and anomalies of the thoracic arteries and veins and expression of discovered candidate genes in the developing heart
Lahm, H.; Jia, M.; Dressen, M.; Wirth, F.; Puluca, N.; Gilsbach, R.; Keavney, B.; Cleuziou, J.; Beck, N.; Bondareva, O.; Dzilic, E.; Burri, M.; Koenig, K. C.; Ziegelmueller, J. A.; Abou-Ajram, C.; Neb, I.; Zhang, Z.; Doppler, S. A.; Mastantuono, E.; Lichtner, P.; Eckstein, G.; Hoerer, J.; Ewert, P.; Priest, J.; Hein, L.; Lange, R.; Meitinger, T.; Cordell, H. J.; Mueller-Myhsok, B.; Krane, M.
10.1101/2020.06.19.161067 — genomics — Posted on 2020-06-20
1683 GenNet framework: interpretable neural networks for phenotype prediction
van Hilten, A.; Kushner, S. A.; Kayser, M.; Ikram, M. A.; Adams, H.; Klaver, C.; Niessen, W. J.; Roshchupkin, G. V.
10.1101/2020.06.19.159152 — bioinformatics — Posted on 2020-06-20
1686 Molecular characterization of pathogenic African trypanosomes in biting flies and camels in surra-endemic areas outside the tsetse fly belt in Kenya
Getahun, M. N.; Villinger, J.; Bargul, J. L.; Orone, A.; Ngiela, J.; Ahuya, P. O.; Muema, J. M.; Saini, R. K.; Torto, B.; Masiga, D. K.
10.1101/2020.06.18.156869 — pathology — Posted on 2020-06-20
1687 Developmental Influences on Symptom Expression in Antipsychotic-Naive First-Episode Psychosis
Bridgwater, M. A.; Bachman, P.; Tervo-Clemmens, B.; Haas, G. L.; Hayes, R.; Luna, B.; Salisbury, D. F.; Jalbrzikowski, M.
10.1101/2020.06.19.160093 — neuroscience — Posted on 2020-06-20
1689 Oscillatory correlates of auditory working memory examined with human electrocorticography
Kumar, S.; Gander, P. E.; Berger, J.; Billig, A. J.; Nourski, K. V.; Oya, H.; Kawasaki, H.; Howard, M. A.; Griffiths, T. D.
10.1101/2020.06.19.161901 — neuroscience — Posted on 2020-06-20
1690 Human Prostate Cancer-Associated Macrophage Subtypes with Prognostic Potential Revealed by Single-cell Transcriptomics
Siefert, J. C.; Cioni, B.; Muraro, M. J.; Alshalalfa, M.; Vivie, J.; van der Poel, H.; Feng, F. Y.; Wessels, L.; Zwart, W.; Bergman, A. M.
10.1101/2020.06.19.160770 — immunology — Posted on 2020-06-20
1691 Developmental pathways regulate cytokine-driven effector and feedback responses in the intestinal epithelium
Lindholm, H. T.; Parmar, N.; Drurey, C. L.; Ostrop, J. L.; Diez-Sanchez, A.; Maizels, R.; Oudhoff, M. J.
10.1101/2020.06.19.160747 — immunology — Posted on 2020-06-20
1692 Combined transient ablation and single cell RNA sequencing reveals the development of medullary thymic epithelial cells
Wells, K. L.; Miller, C. N.; Gschwind, A. R.; Wei, W.; Phipps, J. D.; Anderson, M. S.; Steinmetz, L. M.
10.1101/2020.06.19.160424 — immunology — Posted on 2020-06-20
1693 Cryptosporulation in Kurthia spp. forces a rethinking of asporogenesis in Firmicutes
Filippidou, S.; Fatton, M.; Junier, T.; Berge, M.; Poppleton, D.; Blum, T. B.; Kaminek, M.; Odriozola, A.; Blom, J.; Johnson, S. L.; Abrahams, J. P.; Chain, P. S. G.; Gribaldo, S.; Tocheva, E. I.; Zuber, B.; Viollier, P. H.; Junier, P.
10.1101/2020.06.18.160689 — microbiology — Posted on 2020-06-20
1694 SARS-CoV-2 assays to detect functional antibody responses that block ACE2 recognition in vaccinated animals and infected patients
Kulp, D. W.; Walker, S.; Chokkalingam, N.; Reuschel, E. L.; Purwar, M.; Xu, Z.; Gary, E. Y.; Kim, K. Y.; Schultheis, K.; Walters, J.; Ramos, S.; Smith, T. R. F.; Broderick, K.; Tebas, P.; Patel, A.; Weiner, D. B.
10.1101/2020.06.17.158527 — immunology — Posted on 2020-06-20
1697 Enhancing mitochondrial activity in neurons protects against neurodegeneration in CNS inflammation
Rosenkranz, S. C.; Shaposhnykov, A. A.; Träger, S.; Engler, J.-B.; Witte, M. E.; Roth, V.; Vieira, V.; Paauw, N.; Bauer, S.; Schwencke-Westphal, C.; Bal, L.; Schattling, B.; Pless, O.; van Horssen, J.; Freichel, M.; Friese, M. A.
10.1101/2020.06.19.161091 — neuroscience — Posted on 2020-06-20
1698 Biological invasions alter environmental microbiomes: a meta-analysis
Malacrino, A.; Sadowski, V. A.; Martin, T. K.; Cavichiolli de Oliveira, N.; Brackett, I. J.; Feller, J. D.; Harris, K. J.; Combita Heredia, O.; Vescio, R.; Bennett, A. E.
10.1101/2020.06.17.157883 — ecology — Posted on 2020-06-20
1702 CRISpy-pop: a web tool for designing CRISPR/Cas9-driven genetic modifications in diverse populations
Stoneman, H. R.; Wrobel, R. L.; Place, M.; Graham, M.; Krause, D. J.; De Chiara, M.; Liti, G.; Schacherer, J.; Landick, R.; Gasch, A. P.; Sato, T. K.; Hittinger, C. T.
10.1101/2020.06.19.162099 — genetics — Posted on 2020-06-20
1708 The genomics of trait combinations and their influence on adaptive divergence
Calvert, M. B.; Doellman, M. M.; Feder, J. L.; Hood, G. R.; Meyers, P.; Egan, S. P.; Powell, T. H. Q.; Glover, M.; Tait, C.; Schuler, H.; Berlocher, S.; Smith, J. J.; Nosil, P.; Hahn, D. A.; Ragland, G. J.
10.1101/2020.06.19.161539 — evolutionary biology — Posted on 2020-06-20
1709 Ecogenomics of key prokaryotes in the Arctic Ocean
Royo-Llonch, M.; Sanchez, P.; Ruiz-Gonzalez, C.; Salazar, G.; Pedros-Alio, C.; Labadie, K.; Paoli, L.; Tara Oceans Coordinators, ; Chaffron, S.; Eveillard, D.; Karsenti, E.; Sunagawa, S.; Wincker, P.; Karp-Boss, L.; Bowler, C.; Acinas, S. G.
10.1101/2020.06.19.156794 — ecology — Posted on 2020-06-20
1710 IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer
Bley, N.; Schott, A.; Mueller, S.; Misiak, D.; Lederer, M.; Fuchs, T.; Assmann, C.; Glass, M.; Ihling, C.; Sinz, A.; Pazaitis, N.; Wickenhauser, C.; Vetter, M.; Ungurs, O.; Strauss, H.-G.; Thomssen, C.; Huettelmaier, S.
10.1101/2020.06.19.159905 — cancer biology — Posted on 2020-06-20
1711 SON and SRRM2 form nuclear speckles in human cells
Ilik, I. A.; Malszycki, M.; Luebke, A. K.; Schade, C.; Meierhofer, D.; Aktas, T.
10.1101/2020.06.19.160762 — molecular biology — Posted on 2020-06-20
1712 Microbial dark matter filling the niche in hypersaline microbial mats
Wong, H. L.; MacLeod, F. I.; White, R. A.; Visscher, P. T.; Burns, B. P.
10.1101/2020.06.18.160598 — microbiology — Posted on 2020-06-20
1713 Transgene codon usage drives viral fitness and therapeutic efficacy in oncolytic adenoviruses
Nunez-Manchon, E.; Farrera-Sal, M.; Castellano, G.; Medel, D.; Alemany, R.; Villanueva, E.; Fillat, C.
10.1101/2020.06.19.161026 — bioengineering — Posted on 2020-06-20
1716 Unravelling the genetic basis for the rapid diversification of male genital structures between Drosophila species
Hagen, J. F. D.; Mendes, C. C.; Booth, S. R.; Figueras Jimenez, J.; Tanaka, K. M.; Franke, F. A.; Baudouin-Gonzalez,, L.; Ridgway, A. M.; Arif, S.; Nunes, M. D. S.; McGregor, A. P.
10.1101/2020.06.19.161018 — evolutionary biology — Posted on 2020-06-20
1717 A Biodiversity Composition Map of California Derived from Environmental DNA Metabarcoding and Earth Observation
Lin, M.; Simons, A. L.; Curd, E. E.; Harrigan, R. J.; Schneider, F. D.; Ruiz-Ramos, D. V.; Gold, Z.; Osborne, M. G.; Shirazi, S.; Schweizer, T. M.; Moore, T. N.; Fox, E. A.; Turba, R.; Garcia-Vedrenne, A. E.; Helman, S. K.; Rutledge, K.; Mejia, M. P.; Munguia Ramos, M. N.; Wetzer, R.; Pentcheff, D.; McTavish, E. J.; Dawson, M. N.; Shapiro, B.; Wayne, R. K.; Meyer, R. S.
10.1101/2020.06.19.160374 — ecology — Posted on 2020-06-20
1722 Genetic dissection of Down syndrome-associated alterations in APP/amyloid-β biology using mouse models
Tosh, J. L.; Rhymes, E.; Mumford, P.; Whittaker, H. T.; Pulford, L. J.; Noy, S. J.; Cleverley, K.; Walker, M. L.; Tybulewicz, V. L. J.; Wykes, R. C.; Fisher, E. M. C.; Wiseman, F. K.
10.1101/2020.06.19.162115 — neuroscience — Posted on 2020-06-20
1723 Rapid kinetics of lipid second messengers controlled by a cGMP signalling network coordinates apical complex functions in Toxoplasma tachyzoites
KATRIS, N. J.; YAMARYO-BOTTE, Y.; JANOUSKOVEC, J.; SHUNMUGAM, S.; ARNOLD, C.-S.; YANG, A. S. P.; VARDAKIS, A.; STEWART, R.; SAUERWEIN, R.; McFADDEN, G.; TONKIN, C. J.; CESBRON-DELAUW, M.-F.; BOTTE, C. Y.
10.1101/2020.06.19.160341 — microbiology — Posted on 2020-06-20
1724 A nanobody suite for yeast scaffold nucleoporins provides details of the Nuclear Pore Complex structure
Nordeen, S. A.; Andersen, K. R.; Knockenhauer, K. E.; Ingram, J. R.; Ploegh, H.; Schwartz, T. U.
10.1101/2020.06.19.161075 — biochemistry — Posted on 2020-06-20
1727 Neuronal Classification from Network Connectivity via Adjacency Spectral Embedding
Mehta, K.; Goldin, R. F.; Marchette, D.; Vogelstein, J. T.; Priebe, C. E.; Ascoli, G. A.
10.1101/2020.06.18.160259 — bioinformatics — Posted on 2020-06-20
1729 Evidence of Superior and Inferior Sinoatrial Nodes in the Mammalian Heart
Brennan, J. A.; Chen, Q.; Gams, A.; Dyavanapalli, J.; Mendelowitz, D.; Peng, W.; Efimov, I. R.
10.1101/2020.06.18.159939 — physiology — Posted on 2020-06-20
1732 Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's Disease
Roe, J. M.; Vidal-Pineiro, D.; Sorensen, O.; Brandmaier, A. M.; Duzel, S.; Gonzalez, H. A.; Kievit, R. A.; Knights, E.; Kuhn, S. A.; Lindenberger, U.; Mowinckel, A. M.; Nyberg, L.; Park, D. C.; Pudas, S.; Rundle, M. M.; Walhovd, K. B.; Fjell, A. M.; Westerhausen, R.
10.1101/2020.06.18.158980 — neuroscience — Posted on 2020-06-20
1736 Diminutive, degraded but dissimilar: Wolbachia genomes from filarial nematodes do not conform to a single paradigm
Lefoulon, E.; Clark, T.; Guerrero, R.; Canizales, I.; Cardenas-Callirgos, J. M.; Junker, K.; Vallarino-Lhermitte, N.; Makepeace, B. L.; Darby, A. C.; Foster, J. M.; Martin, C.; Slatko, B. E.
10.1101/2020.06.18.160200 — genomics — Posted on 2020-06-20
1738 Evidence for distinct isotopic composition of sap and tissue water in tree stems: consequences for plant water source identification
Barbeta, A.; Burlett, R.; Martin-Gomez, P.; Frejaville, B.; Devert, N.; Wingate, L.; Domec, J.-C.; Ogee, J.
10.1101/2020.06.18.160002 — ecology — Posted on 2020-06-20
1739 Measuring the accuracy of gridded human population density surfaces: a case study in Bioko Island, Equatorial Guinea
Fries, B.; Smith, D. L.; Wu, S.; Dolgert, A. J.; Guerra, C. A.; Hay, S. I.; Garcia, G. A.; Smith, J. M.; Oyono, J. N. M.; Donfack, O. T.; Nfumu, J. O. O.
10.1101/2020.06.18.160101 — ecology — Posted on 2020-06-20
1740 Detection of differential RNA modifications from direct RNA sequencing of human cell lines
Pratanwanich, P. N.; Yao, F.; Chen, Y.; Koh, C. W. Q.; Hendra, C.; Poon, P.; Goh, Y. T.; Yap, P. M. L.; Jing Yuan, C.; Joo Chng, W.; Ng, S.; Thiery, A.; Goh, W. S. S.; Goeke, J.
10.1101/2020.06.18.160010 — bioinformatics — Posted on 2020-06-20
1742 Short-lived plants have stronger demographic responses to climate
Compagnoni, A.; Levin, S.; Childs, D. Z.; Harpole, S.; Paniw, M.; Romer, G.; Burns, J. H.; Che-Castaldo, J.; Rueger, N.; Kunstler, G.; Bennett, J. M.; Archer, R.; Jones, O. R.; Salguero-Gomez, R.; Knight, T. M.
10.1101/2020.06.18.160135 — ecology — Posted on 2020-06-20
1743 Single cell reconstruction of human basal cell diversity in normal and IPF lung.
Carraro, G.; Mulay, A.; Yao, C.; Mizuno, T.; Konda, B.; Petrov, M.; Lafkas, D.; Arron, J. R.; Hogaboam, C. M.; Chen, P.; Jiang, D.; Noble, P.; Randell, S. H. M.; McQualter, J. L.; Stripp, B.
10.1101/2020.06.19.162305 — cell biology — Posted on 2020-06-20
1745 The SPIRE1 actin nucleator coordinates actin/myosin functions in the regulation of mitochondrial motility
Straub, F.; Welz, T.; Alberico, H.; Brandao, R. O.; Huber, A.; Samol-Wolf, A.; Brakebusch, C.; Woods, D.; Kollmar, M.; Martin-Gonzalez, J.; Kerkhoff, E.
10.1101/2020.06.19.161109 — cell biology — Posted on 2020-06-20
1746 DNA damage inhibits root growth by enhancing cytokinin biosynthesis in Arabidopsis thaliana.
Takahashi, N.; Inagaki, S.; Nishimura, K.; Sakakibara, H.; Antoniadi, I.; Karady, M.; Ljung, K.; Umeda, M.
10.1101/2020.06.19.160838 — plant biology — Posted on 2020-06-20
1747 Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes
Robertson, C. C.; Inshaw, J. R.; Onengut-Gumuscu, S.; Chen, W.-M.; Flores Santa Cruz, D.; Yang, H.; Cutler, A. J.; Crouch, D. J.; Farber, E.; Bridges, S. L.; Edberg, J. C.; Kimberly, R. P.; Buckner, J. H.; Deloukas, P.; Divers, J.; Dabelea, D.; Lawrence, J. M.; Marcovina, S.; Shah, A. S.; Greenbaum, C. J.; Atkinson, M. A.; Gregersen, P. K.; Oksenberg, J. R.; Pociot, F.; Rewers, M. J.; Steck, A. K.; Dunger, D. B.; Wicker, L. S.; Concannon, P.; Todd, J. A.; Rich, S. S.
10.1101/2020.06.19.158071 — genetics — Posted on 2020-06-20
1748 Genetic architecture and gene mapping of cyanide in cassava (Manihot esculenta Crantz.)
Ogbonna, A. C.; Braatz de Andrade, L. R.; Rabbi, I. Y.; Mueller, L. A.; de Oliveira, E. J.; Bauchet, G. J.
10.1101/2020.06.19.159160 — genetics — Posted on 2020-06-20
1753 Role of misfolded tau in the onset and progression of brain toxicity after trauma
Zanier, E. R.; BARZAGO, M. M.; Vegliante, G.; Romeo, M.; Bertani, I.; Natale, C.; Colnaghi, L.; Colombo, L.; Russo, L.; Micotti, E.; Fioriti, L.; Chiesa, R.; Diomede, L.
10.1101/2020.06.18.159301 — neuroscience — Posted on 2020-06-20
1754 Methotrexate carried in lipid core nanoparticles reduces microglial activation and is neuroprotective after ischemic cortical stroke
Pereira, E. L. R.; Dias, M. N.; dos Santos, I. R.; Ramos, A. C.; Hamoy, M.; Feio, D. C. A.; Tavoni, T. M.; da Silva, P. C. M.; Maranhao, R.; Gomes-Leal, W.
10.1101/2020.06.16.155804 — neuroscience — Posted on 2020-06-20
1755 Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model.
Buchan, K. D.; van Gent, M.; Prajsnar, T. K.; Ogryzko, N. V.; de Jong, N.; Kolata, J.; Foster, S. J.; van Strijp, J. A.; Renshaw, S. A.
10.1101/2020.02.18.955021 — immunology — Posted on 2020-06-20
1760 Identification of enzymes for lignocellulose degradation in the genome and transcriptome of the aquatic hyphomycete Clavariopsis aquatica.
Heeger, F.; Bourne, E. C.; Wurzbacher, C.; Funke, E.; Lipzen, A.; He, G.; Ng, V.; Grigoriev, I. V.; Schlosser, D.; Monaghan, M. T.
10.1101/2020.06.18.151886 — ecology — Posted on 2020-06-20
1761 Breast Cancer Cells and Macrophages in a Paracrine-Juxtacrine Loop
Onal, S.; Turker-Burhan, M.; Bati-Ayaz, G.; Yanik, H.; Pesen-Okvur, D.
10.1101/2020.06.16.154294 — cancer biology — Posted on 2020-06-20
1762 Predicting Antibody Developability from Sequence using Machine Learning
Chen, X.; Dougherty, T.; Hong, C.; Schibler, R.; Zhao, Y. C.; Sadeghi, R.; Matasci, N.; Wu, Y.-C.; Kerman, I.
10.1101/2020.06.18.159798 — bioinformatics — Posted on 2020-06-20
1767 Phylogenetic diversity and activity screening of cultivable actinobacteria isolated from marine sponges and associated environments from the western coast of India
Baig, U.; Dahanukar, N.; Shintre, N.; Holkar, K.; Pund, A. I.; Lele, U.; Gujarathi, T.; Patel, K.; Jakati, A.; Singh, R.; Vidwans, H.; Tamhane, V.; Deshpande, N.; Watve, M.
10.1101/2020.01.09.901108 — microbiology — Posted on 2020-06-20
1770 RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development
Mevel, R.; Steiner, I.; Mason, S.; Galbraith, L.; Patel, R.; Fadlullah, M.; Ahmad, I.; Leung, H. Y.; Oliveira, P.; Blyth, K.; Baena, E.; Lacaud, G.
10.1101/2020.06.19.161604 — developmental biology — Posted on 2020-06-20
1771 Multiomics Characterization of Potential Therapeutic Vulnerabilities in Low-grade Serous Ovarian Carcinoma
Shrestha, R.; Fernandez, M. L.; Dawson, A.; Hoenisch, J.; Volik, S.; Lin, Y.-Y.; Anderson, S.; Kim, H.; Haegert, A.; Colborne, S.; McConeghy, B.; Bell, R. H.; Brahmbhatt, S.; DiMattia, G. E.; Le Bihan, S.; Morin, G. B.; Collins, C. C.; Carey, M. S.
10.1101/2020.06.18.135061 — cancer biology — Posted on 2020-06-20
1772 FastPG: Fast clustering of millions of single cells
Bodenheimer, T.; Halappanavar, M.; Jefferys, S.; Gibson, R.; Liu, S.; Mucha, P. J.; Stanley, N.; Parker, J. S.; Selitsky, S. R.
10.1101/2020.06.19.159749 — bioinformatics — Posted on 2020-06-20
1775 Colletotrichum spp. from soybean cause disease on lupin but can also induce plant growth-promoting effects
Wirtz, L.; Massola Junior, N. S.; Rebellato Linhares de Castro, R.; Ruge-Wehling, B.; Schaffrath, U.; Loehrer, M.
10.1101/2020.06.19.160853 — plant biology — Posted on 2020-06-20
1776 A novel synthetic peptide provides neuroprotection and rescues rat cortical neurons from anesthetic-induced cell death and modulation of growth and synaptic assembly
Iqbal, F.; Pehar, M.; Thompson, A.; Azeem, U.; Jahanbakhsh, K.; Jimenez-Tellez, N.; Sabouny, R.; Batool, S.; Ibrahim, A.; Chow, J.; Machiraju, P.; Shutt, T.; Yusuf, K.; Shearer, J.; Rice, T.; Syed, N.
10.1101/2020.06.18.159889 — neuroscience — Posted on 2020-06-20
1777 Single-molecule live cell imaging of the Smc5/6 DNA repair complex
Etheridge, T. J.; Villahermosa, D.; Irmisch, A.; Watson, A. T.; Herbert, A.; Dang, H. Q.; Osborne, M. A.; Oliver, A. W.; Carr, A. M.; Murray, J. M.
10.1101/2020.06.19.148106 — molecular biology — Posted on 2020-06-20
1778 All is fish that comes to the net: metabarcoding for rapid fisheries catch assessment
Russo, T.; Maiello, G.; Talarico, L.; Baillie, C.; Colosimo, G.; D'Andrea, L.; Di Maio, F.; Fiorentino, F.; Franceschini, S.; Garofalo, G.; Scannella, D.; Cataudella, S.; Mariani, S.
10.1101/2020.06.18.159830 — ecology — Posted on 2020-06-20
1780 Plant Genotype Influences Physicochemical Properties of Substrate as well as Bacterial and Fungal Assemblages in the Rhizosphere of Balsam Poplar
Rheault, K.; Lachance, D.; Morency, M.-J.; Thiffault, Évelyne; Guittonny, M.; Isabel, N.; Martineau, C.; Séguin, A.
10.1101/2020.06.19.161398 — ecology — Posted on 2020-06-20
1781 Functional Characterization of the Lin28/let-7 Circuit during Forelimb Regeneration in Ambystoma mexicanum and its Influence on Metabolic Reprogramming
Varela-Rodriguez, H.; Abella-Quintana, D.; Varela-Rodriguez, L.; Gomez-Zepeda, D.; Espinal-Centeno, A.; Caballero-Perez, J.; Ordaz-Ortiz, J.; Cruz-Ramirez, A.
10.1101/2020.06.18.160291 — developmental biology — Posted on 2020-06-20
1783 Tau amyloidogenesis begins with a loss of its conformational polymorphism
Fernandez-Ramirez, M. d. C.; Hervas, R.; Menendez, M.; Laurents, D. V.; Carrion-Vazquez, M.
10.1101/2020.06.18.158923 — biophysics — Posted on 2020-06-20
1786 Photoperiodic induction without light-mediated circadian entrainment in a high arctic resident bird
Appenroth, D.; Melum, V. J.; West, A. C.; Dardente, H.; Hazlerigg, D. G.; Wagner, G. C.
10.1101/2020.06.19.160721 — physiology — Posted on 2020-06-20
1787 Analysis of Gene Expression from Systemic Lupus Erythematosus Synovium Reveals a Profile of Activated Immune Cells and Inflammatory Pathways
Hubbard, E. L.; Catalina, M. D.; Heuer, S.; Bachali, P.; Robl, R. D.; Geraci, N. S.; Grammer, A. C.; Lipsky, P. E.
10.1101/2020.06.19.123307 — immunology — Posted on 2020-06-20
1789 Performance characterization of PCR-free whole genome sequencing for clinical diagnosis
Zhang, N.; Zhou, M.; Zeng, F.; Wang, X.; Liu, F.; Qiao, Z.; Fan, C.; Wang, Y.; Fang, Z.; Dai, W.; Xiang, J.; Sun, J.; Peng, Z.; Song, L.; Sun, Y.
10.1101/2020.06.19.160739 — genetics — Posted on 2020-06-20
1790 A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program
Stilp, A. M.; Emery, L. S.; Broome, J. G.; Buth, E. J.; Khan, A. T.; Laurie, C. A.; Wang, F. F.; Wong, Q.; Chen, D.; D'Augustine, C. M.; Heard-Costa, N. L.; Hohensee, C. R.; Johnson, W. C.; Juarez, L. D.; Liu, J.; Mutalik, K. M.; Raffield, L. M.; Wiggins, K. L.; de Vries, P. S.; Kelly, T. N.; Kooperberg, C.; Natarajan, P.; Peloso, G. M.; Peyser, P. A.; Reiner, A. P.; Arnett, D. K.; Aslibekyan, S.; Barnes, K. C.; Bielak, L. F.; Bis, J. C.; Cade, B. E.; Chen, M.-H.; Correa, A.; Cupples, L. A.; de Andrade, M.; Ellinor, P. T.; Fornage, M.; Franceschini, N.; Gan, W.; Ganesh, S. K.; Graffelman, J.;
10.1101/2020.06.18.146423 — genetics — Posted on 2020-06-20
1791 A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
Kroll, F.; Powell, G. T.; Ghosh, M.; Antinucci, P.; Hearn, T. J.; Tunbak, H.; Lim, S.; Dennis, H. W.; Fernandez, J. M.; Whitmore, D.; Dreosti, E.; Wilson, S. W.; Hoffman, E. J.; Rihel, J.
10.1101/2020.06.04.133462 — genetics — Posted on 2020-06-20
1792 Are we ready to track climate-driven shifts in marine species across international boundaries? - A global survey of scientific bottom trawl data
Maureaud, A. A.; Frelat, R.; Pecuchet, L.; Shackell, N.; Merigot, B.; Pinsky, M. L.; Amador, K.; Anderson, S. C.; Arkhipkin, A.; Auber, A.; Barri, I.; Bell, R.; Belmaker, J.; Beukhof, E.; Camara, M. L.; Guevara-Carrasco, R.; Choi, J.; Christensen, H. T.; Conner, J.; Cubillos, L. A.; Diadhiou, H. D.; Edelist, D.; Emblemsvag, M.; Ernst, B.; Fairweather, T. P.; Fock, H. O.; Friedland, K. D.; Garcia, C. B.; Gascuel, D.; Gislason, H.; Goren, M.; Guitton, J.; Jouffre, D.; Hattab, T.; Hidalgo, M.; Kathena, J. N.; Knuckey, I.; Kide, S. O.; Koen-Alonso, M.; Koopman, M.; Kulik, V.; Leon, J. P.; Levitt-B
10.1101/2020.06.18.125930 — ecology — Posted on 2020-06-20
1793 Germanium nanospheres for ultraresolution picotensiometry of kinesin motors
Sudhaker, S.; Abdosamadi, M. K.; Jachowski, T. J.; Bugiel, M.; Jannasch, A.; Schäffer, E.
10.1101/2020.06.18.159640 — biophysics — Posted on 2020-06-20
1794 Multimodal small-molecule screening for human prion protein binders
Reidenbach, A. G.; Mesleh, M. F.; Casalena, D.; Vallabh, S. M.; Dahlin, J. L.; Leed, A. J.; Chan, A. I.; Usanov, D. L.; Yehl, J. B.; Lemke, C. T.; Campbell, A. J.; Shah, R. N.; Shrestha, O. K.; Sacher, J. R.; Rangel, V. L.; Moroco, J. A.; Sathappa, M.; Nonato, M. C.; Kong, N. T.; Wright, S. K.; Liu, D. R.; Wagner, F. F.; Kaushik, V. K.; Auld, D. S.; Schreiber, S. L.; Minikel, E. V.
10.1101/2020.06.18.159418 — biochemistry — Posted on 2020-06-20
1800 Reward processing electrophysiology in schizophrenia: Effects of age and illness phase
Abram, S. V.; Roach, B.; Holroyd, C. B.; Paulus, M.; Ford, J.; Mathalon, D. H.; Fryer, S. L.
10.1101/2020.06.18.158469 — neuroscience — Posted on 2020-06-20
1801 Sailing in rough waters: examining volatility of fMRI noise
Leppanen, J.; Stone, H.; Lythgoe, D. J.; Williams, S.; Horvath, B.
10.1101/2020.06.19.161570 — neuroscience — Posted on 2020-06-20
1802 Small Non-Coding RNAome of ageing chondrocytes
Balaskas, P.; Green, J. A.; Haqqi, T. M.; Dyer, P.; Kharaz, Y. A.; Fang, Y.; Liu, X.; Welting, T. J.; Peffers, M. J.
10.1101/2020.06.17.156927 — molecular biology — Posted on 2020-06-20
1804 The legacy of recurrent introgression during the radiation of hares
Ferreira, M. S.; Jones, M. R.; Callahan, C. M.; Farelo, L.; Tolesa, Z.; Suchentrunk, F.; Boursot, P.; Mills, L. S.; Alves, P. C.; Good, J. M.; Melo-Ferreira, J.
10.1101/2020.06.19.160283 — evolutionary biology — Posted on 2020-06-20
1807 GENis, an open-source multi-tier forensic DNA information system
Chernomoretz, A.; Balparda, M.; La Grutta, L.; Calabrese, A.; martinez, G.; Escobar, M. S.; Sibilla, G.
10.1101/2020.06.18.159335 — bioinformatics — Posted on 2020-06-20
1815 Brain orchestration of pregnancy and maternal behavior in mice.
Barriere, D. A.; Ella, A.; Szeremeta, F.; Adriaensen, H.; Meme, W.; Chaillou, E.; Migaud, M.; Meme, S.; Levy, F.; Keller, M.
10.1101/2020.05.23.112045 — neuroscience — Posted on 2020-06-19
1816 Spreading depressions and periinfarct spreading depolarizations in the context of cortical plasticity
Sadowska, M.; Mhlhorn, C.; Szewczyk, L. M.; Sredniawa, W.; Szlachcic, A.; Urban, P.; Winiarski, M.; Jablonka, J. A.
10.1101/2020.01.31.927848 — neuroscience — Posted on 2020-06-20
1817 Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer
Belorusova, A. Y.; Bourguet, M.; Hessmann, S.; Chalhoub, S.; Kieffer, B.; Cianferani, S.; Rochel, N.
10.1101/2020.06.17.157305 — molecular biology — Posted on 2020-06-19
1821 Satellite virus diversification through host shifting revealed by novel deltaviruses in vampire bats
Bergner, L.; Orton, R.; Broos, A.; Tello, C.; Becker, D.; Carrera, J.; Patel, A.; Biek, R.; Streicker, D.
10.1101/2020.06.17.156745 — evolutionary biology — Posted on 2020-06-19
1823 Tracing animal genomic evolution with the chromosomal-level assembly of the freshwater sponge Ephydatia muelleri
Kenny, N. J.; Francis, W. R.; Rivera-Vicens, R. E.; Juravel, K.; de Mendoza, A.; Diez-Vives, C.; Lister, R.; Bezares-Calderon, L.; Grombacher, L.; Roller, M.; Barlow, L. D.; Camilli, S.; Ryan, J. F.; Wörheide, G.; Hill, A. L.; Riesgo, A.; Leys, S.
10.1101/2020.02.18.954784 — evolutionary biology — Posted on 2020-06-20
1824 Designing flow regimes to support entire river ecosystems
Tonkin, J. D.; Olden, J. D.; Merritt, D. M.; Reynolds, L. V.; Rogosch, J. S.; Lytle, D. A.
10.1101/2020.01.09.901009 — ecology — Posted on 2020-06-20
1829 DNA Binding Induces a cis to trans Switch in Cre Recombinase to Enable Intasome Assembly
Unnikrishnan, A.; Amero, C. D.; Yadav, D. K.; Stachowski, K.; Potter, D.; Foster, M.
10.1101/2020.05.24.113654 — biophysics — Posted on 2020-06-19
1834 Are isokinetic leg torques and kick velocity reliable predictors for competitive success in taekwondo athletes?
Moreira, P. V. S.; Falco, C.; Menegaldo, L. L.; Goethel, M. F.; de Paula, L. V.; Goncalves, M.
10.1101/2020.06.19.161158 — physiology — Posted on 2020-06-19
1835 Tracing the in Vivo Fate of Nanoparticles with a "Non-Self" Biological Identity
Mohammad-Beigi, H.; Scavenius, C.; Jensen, P. B.; Kjaer-Sorensen, K.; Oxvig, C.; Boesen, T.; Enghild, J. J.; Sutherland, D. S.; Hayashi, Y.
10.1101/2020.03.27.012146 — pharmacology and toxicology — Posted on 2020-06-19
1838 A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1
Meserve, J. H.; Nelson, J. C.; Marsden, K. C.; Hsu, J.; Echeverry, F. A.; Jain, R. A.; Wolman, M. A.; Pereda, A. E.; Granato, M.
10.1101/2020.06.19.161240 — neuroscience — Posted on 2020-06-19
1839 Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women
Trakoshis, S.; Martinez-Canada, P.; Rocchi, F.; Canella, C.; You, W.; Chakrabarti, B.; Ruigrok, A. N.; Bullmore, E.; Suckling, J.; Markicevic, M.; Zerbi, V.; MRC AIMS Consortium, ; Baron-Cohen, S.; Gozzi, A.; Lai, M.-C.; Panzeri, S.; Lombardo, M. V.
10.1101/2020.01.16.909531 — neuroscience — Posted on 2020-06-19
1842 Lentiviral interleukin-10 gene therapy preserves fine motor circuitry and function after a cervical spinal cord injury in male and female mice
Chen, J. Y.; Fu, E. J.; Patel, P. R.; Sawan, H. A.; Moss, K. A.; Hostetler, A. J.; Hocevar, S. E.; Anderson, A. J.; Chestek, C. A.; Shea, L. D.
10.1101/2020.06.05.137257 — neuroscience — Posted on 2020-06-19
1845 The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection
Yao, Z.; Zanini, F.; Kumar, S.; Panpradist, N.; Muniz, A.; Quake, S. R.; Einav, S.
10.1101/2020.02.18.955393 — microbiology — Posted on 2020-06-19
1849 Surprising amount of stasis in repetitive genome content across the Brassicales
Beric, A.; Mabry, M. E.; Harkess, A. E.; Schranz, M. E.; Conant, G. C.; Edger, P. P.; Meyers, B. C.; Pires, J. C.
10.1101/2020.06.15.153296 — evolutionary biology — Posted on 2020-06-19
1853 Integrating multiple experimental data to determine conformational ensembles of an intrinsically disordered protein
Gomes, G.-N. W.; Krzeminski, M.; Namini, A.; Martin, E.; Mittag, T.; Head-Gordon, T.; Forman-Kay, J.; Gradinaru, C.
10.1101/2020.02.05.935890 — biophysics — Posted on 2020-06-19
1856 Local computational methods to improve the interpretability and analysis of cryo-EM maps
Kaur, S.; Gomez-Blanco, J.; Adinarayanan, S.; Khalifa, A.; Sanchez-Garcia, R.; Wrapp, D.; McLellan, J. S.; Bui, K. H.; Vargas, J.
10.1101/2020.05.11.088013 — biophysics — Posted on 2020-06-19
1859 The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling of the gut microbiota
Bermudez-Martin, P.; Becker, J. J.; Fernandez, S. P.; Costa-Campos, R.; Barbosa, S.; Martinez Gili, L.; Myridakis, A.; Dumas, M. E.; Bruneau, A.; Cherbuy, C.; Langella, P.; Chabry, J.; Barik, J.; Le Merrer, J.; Glaichenhaus, N.; Davidovic, L.
10.1101/2020.05.18.101147 — neuroscience — Posted on 2020-06-19
1861 The histone methyltransferase DOT1L is essential for humoral immune responses
Kealy, L.; Di Pietro, A.; Hailes, L.; Scheer, S.; Dalit, L.; Groom, J.; Zaph, C.; Good-Jacobson, K. L.
10.1101/821462 — immunology — Posted on 2020-06-19
1862 Modelling the effects of lymph node swelling on T-cell response
Johnson, S. C.; Frattolin, J.; Edgar, L. T.; Jafarnejad, M.; Moore, J. E.
10.1101/2020.06.19.161232 — immunology — Posted on 2020-06-19
1864 Role of livestock parameters on cattle vulnerability to drought in the coastal semi-arid areas, Kenya
Jack, O. O.; Mathew, M. O.; Owiny, M. O.; Ngugi, J. N.; Ogola, J. G.; Malenga, C. K.; Stephen, M. K.
10.1101/2020.06.19.161273 — ecology — Posted on 2020-06-19
1868 Genetic Distance Calculation Based on Locality Sensitive Hashing
Pathirana, T.; Bandara, S.; Gamage, G.; Silva, G.; Wickramaarachchi, A.; Perera, I.
10.1101/2020.04.06.027250 — bioinformatics — Posted on 2020-06-19
1872 Evolutionary implementation of Bayesian computations
Czegel, D.; Giaffar, H.; Zachar, I.; Tenenbaum, J. B.; Szathmary, E.
10.1101/685842 — evolutionary biology — Posted on 2020-06-19
1875 The common analgesic paracetamol enhances the anti-tumour activity of decitabine through exacerbation of oxidative stress
Gleneadie, H. J.; Baker, A. H.; Batis, N.; Bryant, J.; Jiang, Y.; Clokie, S. J.; Mehanna, H.; Garcia, P.; Gendoo, D. M.; Roberts, S.; Molinolo, A.; Gutkind, S.; Scheven, B. A.; Cooper, P. R.; Khanim, F.; Wiench, M.
10.1101/2020.03.31.017947 — cancer biology — Posted on 2020-06-19
1876 Identification of Six novel missense single nucleotide polymorphisms in MAOA gene predisposing to aggressive behavior. Bioinformatics study.
Abdelmoneim, A. H.; Mustafa, M. I.; Murshed, N. S.; Omer, N. S.; Mohammed, A. I.; Abdulmajed, R. A.; Makhawi, A. M.
10.1101/2019.12.18.880963 — bioinformatics — Posted on 2020-06-19
1878 Nucleotide binding, evolutionary insights and interaction partners of the pseudokinase Unc-51-like kinase 4
Preuss, F.; Chatterjee, D.; Mathea, S.; Shrestha, S.; St-Germain, J.; Saha, M.; Kannan, N.; Raught, B.; Rottapel, R.; Knapp, S.
10.1101/2020.06.18.159293 — biochemistry — Posted on 2020-06-19
1879 Sub-lethal insecticide exposure affects host biting efficiency of Kdr-resistant Anopheles gambiae
Diop, M. M.; Chandre, F.; Rossignol, M.; Porciani, A.; Chateau, M.; Moiroux, N.; Pennetier, C.
10.1101/653980 — animal behavior and cognition — Posted on 2020-06-19
1880 A Novel Therapeutic Approach to Corneal Alkaline Burn Model by Targeting Fidgetin-like 2, a Microtubule Regulator
Wang, J.; Dey, A.; Kramer, A.; Miao, Y.; Liu, J.; Baker, L.; Friedman, J.; Nacharaju, P.; Chuck, R. S.; Zhang, C.; Sharp, D.
10.1101/2020.06.18.159533 — physiology — Posted on 2020-06-19
1883 Physicochemical characterization, toxicity and in vivo biodistribution studies of a discoidal, lipid-based drug delivery vehicle: Lipodisq nanoparticles containing doxorubicin
Torgersen, M. L.; Judge, P. J.; Bada Juarez, J. F.; Pandya, A. D.; Fusser, M.; Davies, C. W.; Maciejewska, M. K.; Yin, D. J.; Maelandsmo, G. M.; Skotland, T.; Watts, A.; Sandvig, K.
10.1101/2020.06.18.159087 — pharmacology and toxicology — Posted on 2020-06-19
1887 Modified HIF expression in CD8+ T cells increases anti-tumor efficacy
Velica, P.; Cunha, P. P.; Vojnovic, N.; Foskolou, I. P.; Bargiela, D.; Gojkovic, M.; Rundqvist, H.; Johnson, R. S.
10.1101/2020.06.18.159137 — immunology — Posted on 2020-06-19
1889 Low-Dose CDK4/6 Inhibitors Induce Presentation of Pathway Specific MHC ligands as Targets for Cancer Immunotherapy
Charles, A.; Bourne, C.; Mun, S. S.; Dao, T.; Aretz, Z.; Korontsvit, T.; Klatt, M.; Scheinberg, D. A.
10.1101/2020.06.18.157800 — cancer biology — Posted on 2020-06-19
1894 Optimised cell systems for the investigation ofhepatitis C virus E1E2 glycoproteins
Kalemera, M. D.; Capella-Pujol, J.; Chumbe, A.; Underwood, A.; Bull, R. A.; Schinkel, J.; Sliepen, K.; Grove, J.
10.1101/2020.06.18.159442 — microbiology — Posted on 2020-06-19
1898 HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal
Sarni, S.; Biswas, B.; Liu, S.; Olson, E. D.; Kitzrow, J. P.; Rein, A.; Wysocki, V. H.; Musier-Forsyth, K.
10.1101/2020.06.18.159822 — biochemistry — Posted on 2020-06-19
1900 No evidence of coronaviruses or other potentially zoonotic viruses in Sunda pangolins (Manis javanica) entering the wildlife trade via Malaysia.
Lee, J.; Hughes, T.; Lee, M.-H.; Field, H.; Rovie-Ryan, J. J.; Sitam, F. T.; Sipangkui, S.; Nathan, S. K. S. S.; Ramirez, D.; Kumar, S. V.; Lasimbang, H.; Epstein, J. H.; Daszak, P.
10.1101/2020.06.19.158717 — molecular biology — Posted on 2020-06-19
1902 The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis
Nampoothiri, S.; Sauve, F.; Ternier, G.; Fernandois, D.; Coelho, C.; Imbernon, M.; Deligia, E.; Perbet, R.; Florent, V.; Baroncini, M.; Pasquier, F.; Trottein, F.; Maurage, C.-A.; Mattot, V.; Giacobini, P.; Rasika, S.; Prevot, V.
10.1101/2020.06.08.139329 — neuroscience — Posted on 2020-06-19
1903 A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages
Dellicour, S.; Durkin, K.; Hong, S. L.; Vanmechelen, B.; Marti-Carreras, J.; Gill, M. S.; Meex, C.; Bontems, S.; Andre, E.; Gilbert, M.; Walker, C.; De Maio, N.; Faria, N. R.; Hadfield, J.; Hayette, M.-P.; Bours, V.; Wawina-Bokalanga, T.; Artesi, M.; Baele, G.; Maes, P.
10.1101/2020.05.05.078758 — evolutionary biology — Posted on 2020-06-19
1905 SYBR green one-step qRT-PCR for the detection of SARS-CoV-2 RNA in saliva
Ganguly, D. R.; Rottet, S.; Yee, S.; Hee, W. Y.; Smith, A. B.; Khin, N. C.; Millar, T.; Fahrer, A.
10.1101/2020.05.29.109702 — molecular biology — Posted on 2020-06-19
1906 High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States
McNamara, R. P.; Caro-Vegas, C.; Landis, J. T.; Moorad, R.; Pluta, L. J.; Eason, A. B.; Thompson, C.; Bailey, A.; Villamor, F. C. S.; Lange, P. T.; Wong, J. P.; Seltzer, T.; Seltzer, J.; Zhou, Y.; Vahrson, W.; Juarez, A.; Meyo, J. O.; Calabre, T.; Broussard, G.; Rivera-Soto, R.; Chappell, D. L.; Baric, R. S.; Damania, B.; Miller, M. B.; Dittmer, D.
10.1101/2020.06.19.161141 — microbiology — Posted on 2020-06-19
1907 Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2 Infected Syrian Hamsters
Brocato, R.; Principe, L.; Kim, R.; Zeng, X.; Williams, J.; Liu, Y.; Li, R.; Smith, J.; Golden, J.; Gangemi, D.; Youssef, S.; Wang, Z.; Glanville, J.; Hooper, J.
10.1101/2020.06.19.161612 — microbiology — Posted on 2020-06-19
1908 Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins
Diez, J. M.; Romero, C.; Vergara Alert, J.; Bello Perez, M.; Rodon, J.; Honrubia, J. M.; Segales, J.; Sola, I.; Enjuanes, L.; Gajardo, R.
10.1101/2020.06.19.160879 — immunology — Posted on 2020-06-19
1909 Proteotyping SARS-CoV-2 virus from nasopharyngeal swabs: a proof-of-concept focused on a 3 min mass spectrometry window
Gouveia, D.; Miotello, G.; Gallais, F.; Gaillard, J.-C.; Debroas, S.; Bellanger, L.; Lavigne, J.-P.; Sotto, A.; Grenga, L.; Pible, O.; Armengaud, J.
10.1101/2020.06.19.161000 — microbiology — Posted on 2020-06-19
1913 ARDS and Cytokine Storm in SARS-CoV-2 Infected Caribbean Vervets
Blair, R. V.; Vaccari, M.; Doyle-Meyers, L. A.; Roy, C. J.; Russell-Lodrigue, K.; Fahlberg, M.; Monjure, C. J.; Beddingfield, B.; Plante, K. S.; Plante, J. A.; Weaver, S. C.; Qin, X.; Midkiff, C. C.; Lehmicke, G.; Golden, N.; Threeton, B.; Penney, T.; Allers, C.; Barnes, M. B.; Pattison, M.; Datta, P. K.; Maness, N. J.; Birnbaum, A.; Bohm, R. P.; Rappaport, J.
10.1101/2020.06.18.157933 — pathology — Posted on 2020-06-19
1915 Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2
Dittmar, M.; Lee, J. S.; Whig, K.; Segrist, E.; Li, M.; Jurado, K.; Samby, K.; Ramage, H.; Schultz, D.; Cherry, S.
10.1101/2020.06.19.161042 — microbiology — Posted on 2020-06-19
1916 A single dose of recombinant VSV-{triangleup}G-spike vaccine provides protection against SARS-CoV-2 challenge
Yahalom-Ronen, Y.; Tamir, H.; Melamed, S.; Politi, B.; Shifman, O.; Achdout, H.; B. Vitner, E.; Israeli, O.; Milrot, E.; Stein, D.; Cohen-Gihon, I.; Lazar, S.; Gutman, H.; Glinert, I.; Cherry, L.; Vagima, Y.; Lazar, S.; Weiss, S.; Ben-Shmuel, A.; Avraham, R.; Puni, R.; Lupu, E.; Bar David, E.; Sittner, A.; Erez, N.; Zichel, R.; Mamroud, E.; Mazor, O.; Levy, H.; Laskar, O.; Yitzhaki, S.; C. Shapira, S.; Zvi, A.; Beth-Din, A.; Paran, N.; Israely, T.
10.1101/2020.06.18.160655 — microbiology — Posted on 2020-06-19
1917 Identification of a critical horseshoe-shaped region in the nsp5 (Mpro, 3CLpro) protease interdomain loop (IDL) of coronavirus mouse hepatitis virus (MHV)
Nick, B. C.; Pandya, M. C.; Lu, X.; Franke, M. E.; Callahan, S. M.; Hasik, E. F.; Berthrong, S. T.; Denison, M. R.; Stobart, C. C.
10.1101/2020.06.18.160671 — microbiology — Posted on 2020-06-19
1918 Phylogenetic pattern of SARS-CoV-2 from COVID-19 patients from Bosnia and Herzegovina: lessons learned to optimize future molecular and epidemiological approaches
Goletic, T.; Konjhodzic, R.; Fejzic, N.; Goletic, S.; Eterovic, T.; Softic, A.; Kustura, A.; Salihefendic, L.; Ostojic, M.; Travar, M.; Mrdjen, V.; Tihic, N.; Jazic, S.; Musa, S.; Marjanovic, D.; Hukic, M.
10.1101/2020.06.19.160606 — genetics — Posted on 2020-06-19
1919 Mechanism and inhibition of SARS-CoV-2 PLpro
Klemm, T.; Ebert, G.; Calleja, D. J.; Allison, C. C.; Richardson, L. W.; Bernardini, J. P.; Lu, B. G. C.; Kuchel, N. W.; Grohmann, C.; Shibata, Y.; Gan, Z. Y.; Cooney, J. P.; Doerflinger, M.; Au, A. E.; Blackmore, T. R.; Geurink, P. P.; Ovaa, H.; Newman, J.; Riboldi-Tunnicliffe, A.; Czabotar, P. E.; Mitchell, J. P.; Feltham, R.; Lechtenberg, B. C.; Lowes, K. N.; Dewson, G.; Pellegrini, M.; Lessene, G.; Komander, D.
10.1101/2020.06.18.160614 — biochemistry — Posted on 2020-06-19
1920 Antiviral treatment of SARS-CoV-2-infected hamsters reveals a weak effect of favipiravir and a complete lack of effect for hydroxychloroquine
Kaptein, S. J.; Jacobs, S.; Langendries, L.; Seldeslachts, L.; ter Horst, S.; Liesenborghs, L.; Hens, B.; Vergote, V.; Heylen, E.; Maas, E.; De Keyzer, C.; Bervoets, L.; Rymenants, J.; Van Buyten, T.; Thibaut, H. J.; Dallmeier, K.; Boudewijns, R.; Wouters, J.; Augustijns, P.; Verougstraete, N.; Cawthorne, C.; Weynand, B.; Annaert, P.; Spriet, I.; Vande Velde, G.; Neyts, J.; Rocha-Pereira, J.; Delang, L.
10.1101/2020.06.19.159053 — microbiology — Posted on 2020-06-19
1921 Dog Savior: Immediate Scent-Detection of SARS-COV-2 by Trained Dogs
Vesga, O.; Valencia, A. F.; Mira, A.; Ossa, F.; Ocampo, E.; Agudelo Perez, M.; Ciouderis, k.; Perez, L.; Cardona, A.; Aguilar Perez, Y.; Gonzalez, J. M.; Catano Correa, J. C.; Agudelo Berruecos, Y.; Hernandez-Ortiz, J. P.; Osorio, J. E.
10.1101/2020.06.17.158105 — microbiology — Posted on 2020-06-19
1922 No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
van Dorp, L.; Richard, D.; Tan, C. C.; Shaw, L. P.; Acman, M.; Balloux, F.
10.1101/2020.05.21.108506 — genomics — Posted on 2020-06-19
1925 Structural mimicry confers robustness in the cyanobacterial circadian clock
Heisler, J.; Swan, J. A.; Palacios, J. G.; Sancar, C.; Ernst, D. C.; Spangler, R. K.; Bagshaw, C. R.; Tripathi, S.; Crosby, P.; Golden, S. S.; Partch, C. L.; LiWang, A.
10.1101/2020.06.17.158394 — biochemistry — Posted on 2020-06-19
1926 Reduced cue-induced reinstatement of cocaine seeking behavior in Plcb1+/- mice
Cabana-Dominguez, J.; Martin-Garcia, E.; Gallego-Roman, A.; Maldonado, R.; Fernandez-Castillo, N.; Cormand, B.
10.1101/2020.06.18.158964 — animal behavior and cognition — Posted on 2020-06-19
1935 TBDB: A database of structurally annotated T-box riboswitch-tRNA pairs
Marchand, J. A.; Smela, M. D. P.; Jordan, T. H. H.; Narasimhan, K.; Church, G.
10.1101/2020.06.17.157016 — bioinformatics — Posted on 2020-06-19
1936 Reconstitution of an intact clock that generates circadian DNA binding in vitro
Chavan, A. G.; Ernst, D. C.; Fang, M.; Sancar, C.; Partch, C. L.; Golden, S. S.; LiWang, A.
10.1101/2020.06.18.158576 — biochemistry — Posted on 2020-06-19
1939 Balanced JAK/STAT signaling is critical to maintain the functional and structural integrity of the Drosophila respiratory epithelium
Niu, X.; Fink, C.; Kallsen, K.; Mincheva, V.; Franzenburg, S.; Prange, R. D.; Bossen, J.; Heine, H.; Roeder, T.
10.1101/2020.06.19.160929 — cell biology — Posted on 2020-06-19
1941 Early diversity in the firing pattern of embryonic Renshaw cells: just a synergy between two opposite voltage-dependent currents
Boeri, J.; Meunier, C.; Le Corronc, H.; Branchereau, P.; Timofeeva, Y.; Lejeune, F.-X.; Mouffle, C.; Arulkandarajah, H.; Mangin, J. M.; Legendre, P.; Czarnecki, A.
10.1101/2020.06.18.158931 — neuroscience — Posted on 2020-06-19
1945 Genome scale epigenomic analysis of response to acute stress in the European sea bass (Dicentrarchus labrax, L.)
KRICK, M. V.; DESMARAIS, E.; SAMARAS, A.; GUERET, E.; DIMITROGLOU, A.; PAVLIDIS, M.; TSIGENOPOULOS, C. S.; GUINAND, B.
10.1101/2020.06.19.160812 — genomics — Posted on 2020-06-19
1946 Transcriptomic signatures associated with regional cortical thickness changes in Parkinson's disease
Keo, A.; Dzyubachyk, O.; van der Grond, J.; van Hilten, J. J.; Reinders, M.; Mahfouz, A.
10.1101/2020.06.19.158808 — bioinformatics — Posted on 2020-06-19
1950 Building memories on prior knowledge: behavioral and fMRI evidence of impairment in early Alzheimer's Disease
Jonin, P.-Y.; Duche, Q.; Bannier, E.; Corouge, I.; Ferre, J.-C.; Belliard, S.; Barillot, C.; Barbeau, E. J.
10.1101/2020.06.17.154104 — neuroscience — Posted on 2020-06-19
1951 Team flow is a unique brain state associated with enhanced information integration and neural synchrony
Shehata, M.; Cheng, M.; Leung, A.; Tsuchiya, N.; Wu, D.-A.; Tseng, C.-h.; Nakauchi, S.; Shimojo, S.
10.1101/2020.06.17.157990 — neuroscience — Posted on 2020-06-19
1955 Polypeptide collapse modulation and folding stimulation by GroEL-ES
Naqvi, M. M.; Avellaneda, M. J.; Roth, A.; Koers, E. J.; Sunderlikova, V.; Kramer, G. J.; Rye, H. S.; Tans, S. J.
10.1101/2020.06.17.157057 — biophysics — Posted on 2020-06-19
1961 Mechanical control of tissue shape and morphogenetic flows during vertebrate body axis elongation
Banavar, S. P.; Carn, E. K.; Rowghanian, P.; Stooke-Vaughan, G.; Kim, S.; Campas, O.
10.1101/2020.06.17.157586 — biophysics — Posted on 2020-06-19
1964 Whole genome doubling confers unique genetic vulnerabilities on tumor cells
Quinton, R. J.; Didomizio, A.; Vittoria, M. A.; Ticas, C. J.; Patel, S.; Koga, Y.; Kotynkova, K.; Vakhshoorzadeh, J.; Hermance, N.; Kuroda, T. S.; Parulekar, N.; Taylor, A. M.; Manning, A. L.; Campbell, J. D.; Ganem, N. J.
10.1101/2020.06.18.159095 — cancer biology — Posted on 2020-06-19
1965 Conclusive Identification of Senescent T Cells Reveals Their Abundance in Aging Humans
Martinez Zamudio, R. I.; Dewald, H. K.; Vasilopoulos, T.; Gittens-Williams, L.; Fitzgerald-Bocarsly, P.; Herbig, U.
10.1101/2020.06.17.157826 — cell biology — Posted on 2020-06-19
1966 Maladaptive nutrient signalling sustains the m.3243A>G mtDNA mutation
Chung, C.-Y.; Singh, K.; Kotiadis, V. N.; Ahn, J. H.; Kabir, L.; Topley, E.; Tan, J.; Andrews, W. D.; Plotegher, N.; Guella, G.; Pitceathly, R. D. S.; Szabadkai, G.; Yuneva, M.; Duchen, M. R.
10.1101/2020.06.18.159103 — cell biology — Posted on 2020-06-19
1967 Evaluation of the performance of SARS-CoV-2 serological tools and their positioning in COVID-19 diagnostic strategies.
Velay, A.; Gallais, F.; Benotmane, I.; Wendling, M.-J.; Danion, F.; Collange, O.; De Seze, J.; Schmidt-Mutter, C.; Schneider, F.; Bilbault, P.; Meziani, F.; Fafi-Kremer, S.
10.1101/2020.06.16.156166 — microbiology — Posted on 2020-06-19
1969 Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations
Kar, S. P.; Lindstroem, S.; Hung, R.; Lawrenson, K.; Schmidt, M.; O'Mara, T.; Glubb, D.; Tyrer, J.; Schildkraut, J.; Chang-Claude, J.; Alsulimani, A.; Anton, F.; Beeghly-Fadiel, A.; Bjorge, L.; Bodelon, C.; Brauch, H.; Burghaus, S.; Campa, D.; Carney, M.; Chen, Z.; Daly, M.; du Bois, A.; Ekici, A.; Ewing, A.; Fasching, P.; Flanagan, J. M.; Gawelko, J.; Giles, G.; Hamilton, R.; Harris, H.; Heitz, F.; Hildebrandt, M.; Hillemanns, P.; Huang, R.-Y.; Imaz, L.; Irmejs, A.; Jakubowska, A.; Jensen, A.; John, E.; Kannisto, P.; Karlan, B.; Khusnutdinova, E.; Kiemeney, L.; Kjaer, S.; Klapdor, R.; Kleiblo
10.1101/2020.06.16.146803 — genetics — Posted on 2020-06-19
1970 Multiple epigenetic layers accompany the spatial distribution of ribosomal genes in Arabidopsis
Dvorackova, M.; Kutashev, K. O.; Franek, M.; Diamanti, K.; Komorowski, J.; Olsinova, M.
10.1101/2020.06.17.156299 — cell biology — Posted on 2020-06-19
1971 Selective vulnerability of aneuploid human cancer cells to inhibition of the spindle assembly checkpoint
Cohen-Sharir, Y.; McFarland, J. M.; Abdusamad, M.; Marquis, C.; Tang, H.; Ippolito, M. R.; Bernhard, S. V.; Laue, K.; Malaby, H. L.; Jones, A.; Kazachkova, M.; Lyons, N.; Nagaraja, A.; Bass, A. J.; Beroukhim, R.; Santaguida, S.; Stumpff, J.; Golub, T. R.; Storchova, Z.; Ben-David, U.
10.1101/2020.06.18.159038 — cancer biology — Posted on 2020-06-19
1972 Single molecule microscopy reveals key physical features of repair foci in living cells
Mine-Hattab, j.; Heltberg, M.; Villemeur, M.; Guedj, C.; Mora, T.; Walczak, A. M.; Dahan, M.; Taddei, A.
10.1101/2020.06.18.160085 — biophysics — Posted on 2020-06-19
1974 Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network.
Hutchings, J.; Stancheva, V. G.; Brown, N. R.; Cheung, A. M.; Miller, E. A.; Zanetti, G.
10.1101/2020.06.18.159608 — cell biology — Posted on 2020-06-19
1975 Rub1/NEDD8, a ubiquitin-like modifier, is also a ubiquitin modifier
Zerath Gurevich, S.; Sinha, A.; Longworth, J.; Singh, R. K.; Lemma, B. E.; Thakur, A.; Popp, O.; Kornitzer, D.; Reis, N.; Scheffner, M.; Dittmar, G.; Pick, E.; Fushman, D.; Glickman, M. H.
10.1101/2020.06.18.159145 — biochemistry — Posted on 2020-06-19
1980 Molecular mode of action of an Acyl Protein thioesterase
Abrami, L.; Audagnotto, M.; Ho, S.; Marcaida, M. J.; Mesquita, F.; Anward, M.; Sandoz, P. A.; Fonti, G.; Pojer, F.; Dal Peraro, M.; van der Goot, F. G.
10.1101/2020.06.18.157545 — cell biology — Posted on 2020-06-19
1981 Pretreatment with LCK Inhibitors Chemosensitizes Cisplatin-Resistant Endometrioid Ovarian Tumors
Crean-Tate, K. K.; Braley, C.; Dey, G.; Esakov, E.; Saygin, C.; Trestan, A.; Silver, D. J.; Turaga, S. M.; Connor, E. V.; Debernardo, R.; Michener, C. M.; Rose, P. G.; Lathia, J.; Reizes, O.
10.1101/2020.06.18.154732 — cancer biology — Posted on 2020-06-19
1983 Optimizing spectral quality with quantum dots to enhance crop yield in controlled environments
Parrish, C. H.; Hebert, D.; Jackson, A.; Ramasamy, K.; McDaniel, H.; Giacomelli, G. A.; Bergren, M. R.
10.1101/2020.06.17.157487 — plant biology — Posted on 2020-06-19
1984 Novel mTORC1 inhibitors kill Glioblastoma stem cells
Sandoval, J. A.; Tomilov, A.; Datta, S.; Allen, S.; O'Donnell, R.; Angelastro, J.; Cortopassi, G.
10.1101/2020.06.17.157735 — pharmacology and toxicology — Posted on 2020-06-19
1985 Neural surprise in somatosensory Bayesian learning
Gijsen, S.; Grundei, M.; Lange, R. T.; Ostwald, D.; Blankenburg, F.
10.1101/2020.06.18.158915 — neuroscience — Posted on 2020-06-19
1991 The mitochondrial carrier SFXN1 is critical for Complex III integrity and cellular metabolism
Acoba, M. G.; Alpergin, E. S. S.; Renuse, S.; Fernandez-del-Rio, L.; Lu, Y.-W.; Clarke, C. F.; Pandey, A.; Wolfgang, M. J.; Claypool, S. M.
10.1101/2020.06.18.157495 — biochemistry — Posted on 2020-06-19
1993 Ten Genetic Loci Identified for Milk Yield, Fat, and Protein in Holstein Cattle
Liu, L.; Zhou, J.; Chen, C. J.; Zhang, J.; Wen, W.; Tian, J.; Zhang, Z.; Gu, Y.
10.1101/2020.06.17.158386 — genomics — Posted on 2020-06-19
1995 Inferring Tumor Progression in Large Datasets
Mohaghegh Neyshabouri, M.; Jun, S.-H.; Lagergren, J.
10.1101/2020.06.18.159228 — cancer biology — Posted on 2020-06-19
1997 The role of trehalose 6-phosphate in shoot branching - local and non-local effects on axillary bud outgrowth in arabidopsis rosettes
Fichtner, F.; Barbier, F. F.; Annunziata, M. G.; Feil, R.; Olas, J. J.; Mueller-Roeber, B.; Stitt, M.; Beveridge, C. A.; Lunn, J.
10.1101/2020.06.18.158568 — plant biology — Posted on 2020-06-19
1999 Norepinephrine, olfactory bulb and memory stability
LINSTER, C.; Midroit, M.; Forest, J.; Thenaisie, Y.; Cho, C.; Richard, M.; Didier, A.; Mandairon, N.
10.1101/2020.06.17.153502 — neuroscience — Posted on 2020-06-19
2001 Embryonic Tissues as Active Foams
Kim, S.; Pochitaloff, M.; Stooke-Vaughan, G.; Campas, O.
10.1101/2020.06.17.157909 — biophysics — Posted on 2020-06-19
2002 The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 deafness
Jiang, F.; Takagi, Y.; Shams, A.; Heissler, S. M.; Friedman, T. B.; Sellers, J. R.; Bird, J. E.
10.1101/2020.06.17.155424 — biochemistry — Posted on 2020-06-19
2004 Neural correlates of temporal presentness in theprecuneus: a crosslinguistic fMRI study based on speech stimuli
Tang, L.; Takahashi, T.; Shimada, T.; Komachi, M.; Imanishi, N.; Nishiyama, Y.; Iida, T.; Otsu, Y.; Kitazawa, S.
10.1101/2020.06.17.158485 — neuroscience — Posted on 2020-06-18
2005 The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition
Tristan-Ramos, P.; Rubio-Roldan, A.; Peris, G.; Sanchez, L.; Amador-Cubero, S.; Viollet, S.; Cristofari, G.; Heras, S. R.
10.1101/2020.06.18.158667 — molecular biology — Posted on 2020-06-19
2006 SARS-CoV-2 Whole Genome Amplification and Sequencing for Effective Population-Based Surveillance and Control of Viral Transmission
Harilal, D.; Ramaswamy, S.; Loney, T.; Alsuwaidi, H.; Khansaheb, H.; AlKhajeh, A.; Varghese, R.; Deesi, Z.; Nowotny, N.; Alsheikh-Ali, A.; Abou Tayoun, A.
10.1101/2020.06.06.138339 — genomics — Posted on 2020-06-18
2007 Portiera gives new clues on the evolutionary history of whiteflies
Santos-Garcia, D.; Mestre-Rincon, N.; OUVRARD, D.; Zchori-Fein, E.; Morin, S.
10.1101/2020.06.17.158493 — evolutionary biology — Posted on 2020-06-18
2009 Tunable phenotypic variability through an autoregulatory alternative sigma factor circuit
Schwall, C. P.; Loman, T.; Martins, B. M. C.; Cortijo, S.; Villava, C.; Kusmartsev, V.; Livesey, T.; Saez, T.; Locke, J. C. W.
10.1101/2020.06.18.158790 — systems biology — Posted on 2020-06-18
2012 TBK1 interacts with tau and enhances neurodegeneration in tauopathy
Abreha, M. H.; Ojelade, S.; Dammer, E. B.; McEachin, Z. T.; Duong, D. M.; Gearing, M.; Bassell, G. J.; Lah, J. J.; Levey, A. I.; Shulman, J. M.; Seyfried, N. T.
10.1101/2020.06.17.157552 — neuroscience — Posted on 2020-06-18
2013 HNRNPM controls circRNA biogenesis and splicing fidelity to sustain prostate cancer cell fitness
Ho, S. Y. J.; Low, D.; Schwarz, M.; Incarnato, D.; Gay, F.; Tabaglio, T.; Zhang, J.; Wollmann, H.; Chen, P. L.; An, O.; Chan, T. H. M.; Hall Hickman, A.; Zheng, S.; Roudko, V.; Chen, S.; Ahmed, M.; He, H. H.; Greenbaum, B. D.; Marazzi, I.; Serresi, M.; Gargiulo, G.; Oliviero, S.; Wee, D. K. B.; Guccione, E.
10.1101/2020.06.17.157537 — genomics — Posted on 2020-06-18
2014 Population genomics of North American northern pike: variation and sex-specific signals from a chromosome-level, long read genome assembly
Johnson, H. A.; Rondeau, E. B.; Minkley, D. R.; Leong, J. S.; Whitehead, J.; Despins, C. A.; Gowen, B. E.; Collyard, B. J.; Whipps, C. M.; Farrell, J. M.; Koop, B. F.
10.1101/2020.06.18.157701 — genomics — Posted on 2020-06-18
2016 NUMT dumping: validated removal of nuclear pseudogenes from mitochondrial metabarcode data
Andujar, C.; Creedy, T. J.; Arribas, P.; Lopez, H.; Salces-Castellano, A.; Perez-Delgado, A.; Vogler, A. P.; Emerson, B. C.
10.1101/2020.06.17.157347 — evolutionary biology — Posted on 2020-06-18
2018 Single cell RNA sequence analysis of human bone marrow samples reveals new targets for isolation of skeletal stem cells using DNA-coated gold nanoparticles
Matthews, E.; Lanham, S.; Kyriazi, M.-E.; Alexaki, K.; El-Sagheer, A.; Brown, T.; Kanaras, A.; West, J.; MacArthur, B. D.; Stumpf, P. S.; Oreffo, R. O. C.
10.1101/2020.06.17.156836 — cell biology — Posted on 2020-06-18
2019 Fluorescence Microscopy Datasets for Training Deep Neural Networks
Hagen, G. M.; Bendesky, J.; Machado, R.; Nguyen, T.-A.; Kumar, T.; Ventura, J.
10.1101/2020.06.17.158097 — bioinformatics — Posted on 2020-06-18
2020 Biophysical characterization of the human K0513 protein
Nemukondeni, N.; Arowolo, A.; Shonhai, A.; Zininga, T.; Burger, A.
10.1101/2020.06.18.158949 — biochemistry — Posted on 2020-06-18
2025 High Gamma Cortical Processing of Continuous Speech in Younger and Older Listeners
Kulasingham, J. P.; Brodbeck, C.; Presacco, A.; Kuchinsky, S. E.; Anderson, S.; Simon, J. Z.
10.1101/2019.12.19.883314 — neuroscience — Posted on 2020-06-18
2026 Small RNAome of ageing chondrocytes
Balaskas, P.; Green, J. A.; Haqqi, T. M.; Dyer, P.; Ashraf, Y.; Fang, Y.; Liu, X.; Welting, T. J.; Peffers, M. J.
10.1101/2020.06.17.156927 — molecular biology — Posted on 2020-06-18
2027 Novel functional insights from the Plasmodium falciparum sporozoite-specific proteome by probabilistic integration of 26 studies
Meerstein-Kessel, L.; Venhuizen, J.; Garza, D.; Vos, E. J.; Obiero, J. M.; Felgner, P. L.; Sauerwein, R. W.; Peters, M.; Yang, A. S. P.; Huynen, M. A.
10.1101/2020.06.18.158899 — microbiology — Posted on 2020-06-18
2031 HES1 is a critical mediator of the SHH-GLI3 axis in regulating digit number
Hilton, M. J.; Sharma, D.; Mirando, A. J.; Leinroth, A.; Long, J. T.; Karner, C. M.
10.1101/2020.06.17.158501 — developmental biology — Posted on 2020-06-18
2032 TOP2A substitution enhances topoisomerase activity and causes transcriptional dysfunction in glioblastoma patients
Gielniewski, B.; Poleszak, K.; Roura, A.-J.; Szadkowska, P.; Krol, S. K.; Guzik, R.; Wiechecka, P.; Maleszewska, M.; Kaza, B.; Marchel, A.; Czernicki, T.; Koziarski, A.; Zielinski, G.; Styk, A.; Kawecki, M.; Szczylik, C.; Czepko, R.; Banach, M.; Kaspera, W.; Szopa, W.; Bujko, M.; Czapski, B.; Zabek, M.; Izycka-Swieszewska, E.; Kloc, W.; Nauman, P.; Wojtas, B.; Kaminska, B.
10.1101/2020.06.17.158477 — cancer biology — Posted on 2020-06-18
2036 Mechanism Underlying Anti-Markovnikov Addition in the Reaction of Pentalenene Synthase
Matos, J. O.; Kumar, R. P.; Ma, A. C.; Patterson, M.; Krauss, I. J.; Oprian, D. D.
10.1101/2020.06.17.157867 — biochemistry — Posted on 2020-06-18
2038 Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors
Ding, P.; Sakai, T.; Shrestha, R. K.; Perez, N. M.; Guo, W.; Ngou, B. P. M.; He, S.; Liu, C.; Feng, X.; Zhang, R.; Vandepoele, K.; MacLean, D.; Jones, J. D.
10.1101/2020.06.17.157040 — plant biology — Posted on 2020-06-18
2039 Prime editing is achievable in the tetraploid potato, but needs improvement
Veillet, F.; Kermarrec, M.-P.; Chauvin, L.; Guyon-Debast, A.; Chauvin, J.-E.; Gallois, J.-L.; Nogue, F.
10.1101/2020.06.18.159111 — plant biology — Posted on 2020-06-18
2042 Low Dose Hyperoxia Primes Airways for Fibrosis in Mice after Influenza A Infection
Dylag, A. M.; Haak, J.; Warren, R.; Yee, M.; Pryhuber, G. S.; O'Reilly, M. A.
10.1101/2020.06.17.157610 — physiology — Posted on 2020-06-18
2043 Comparative assessment of the effects of bumped kinase inhibitors on early zebrafish embryo development and pregnancy in mice.
Anghel, N.; Winzer, P. A.; Imhof, D.; Mueller, J.; Langa Oliva, X.; Rieder, J.; Barrett, L. K.; Rao Vidadala, R. S. R. V.; Huang, W.; Choi, R.; Hulverson, M.; Whitman, G.; Arnold, S.; Van Voorhis, W.; Ojo, K. K.; Maly, D.; Fan, E.; Hemphill, A.
10.1101/2020.06.17.157529 — pathology — Posted on 2020-06-18
2047 Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding
Wang, X.; Gao, L.; Jiao, C.; Stravoravdis, S.; Hosmani, P.; Saha, S.; Zhang, J.; Mainiero, S.; Strickler, S.; Catala, C.; Martin, G.; Mueller, L.; Vrebalov, J.; Giovannoni, J.; Wu, S.; Fei, Z.
10.1101/2020.06.17.157859 — genomics — Posted on 2020-06-18
2048 Human Whole Genome Sequencing in South Africa
Glanzmann, B.; Jooste, T.; Ghoor, S.; Gordon, R.; Mia, R.; Mao, R.; Li, H.; Charls, P.; Douman, C.; Kotze, M.; Peeters, A.; Loots, G.; Esser, M.; Tiemessen, C.; Wilkinson, R.; Louw, J.; Gray, G.; Warren, R.; Moller, M.; Kinnear, C.
10.1101/2020.06.10.144402 — genomics — Posted on 2020-06-18
2049 A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
Kroll, F.; Powell, G. T.; Ghosh, M.; Antinucci, P.; Hearn, T. J.; Tunbak, H.; Lim, S.; Dennis, H. W.; Fernandez, J. M.; Whitmore, D.; Dreosti, E.; Wilson, S. W.; Hoffman, E. J.; Rihel, J.
10.1101/2020.06.04.133462 — genetics — Posted on 2020-06-18
2051 Smooth muscle-specific MMP17 (MT4-MMP) defines the intestinal ECM niche
Martin-Alonso, M.; Lindholm, H.; Iqbal, S.; Vornewald, P.; Hoel, S.; Damen, M.; Altelaar, A. F. M.; Katajisto, P.; Arroyo, A. G.; Oudhoff, M. J.
10.1101/2020.06.18.147769 — cell biology — Posted on 2020-06-18
2052 Activation of the Anaphase Promoting Complex reverses multiple drug resistant cancer
Aranson, T.; MacDonald-Dickinson, V.; Davies, G. F.; Gaunt, C.; Lubanova, L.; Trost, B.; Waldner, M.; Baldwin, P.; Borrowood, D.; Marwood, H.; Gillespie, Z. E.; Vizeacoumar, F.; Vizeacoumar, F.; Eskiw, C. H.; Kusalik, A.; Harkness, T. A. A.
10.1101/2020.05.26.115337 — cancer biology — Posted on 2020-06-18
2059 Wild emmer introgressions alter root-to-shoot growth dynamics under water stress
Bacher, H.; Zhu, f.; Gao, T.; Liu, K.; Dhatt, B.; Awada, T.; Zhang, C.; Distelfeld, A.; Yu, H.; Peleg, Z.; Walia, H.
10.1101/2020.06.17.157461 — plant biology — Posted on 2020-06-18
2060 A Peptide of the Amino-Terminus of GRK2 Induces Hypertrophy and Yet Elicits Cardioprotection after Pressure Overload
Schumacher, S. M.; Bledzka, K. M.; Grondolsky, J.; Roy, R.; Gao, E.; Chuprun, J. K.; Koch, W. J.
10.1101/2020.06.18.159194 — physiology — Posted on 2020-06-18
2061 Antibiotic concentrations in the sinonasal secretions and tissue in CRS patients after oral therapy: a randomized trial
Siu, J.; Klingler, L.; Wang, Y.; Hung, C.-T.; Jeong, S. H.; Smith, S.; Tingle, M.; Mackenzie, B.; Biswas, K.; Douglas, R. G.
10.1101/2020.06.17.158535 — pharmacology and toxicology — Posted on 2020-06-18
2064 Identification and Mechanistic Characterization of a Novel Peptide Inhibitor of Glycogen Synthase Kinase (GSK3) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein
Saundh, S.; Patnaik, D.; Gagne, S.; Bishop, J.; Lipsit, S.; Amat, S.; Pujari, N.; Krishnan, A. K.; Bigsby, R.; Murphy, M.; Tsai, L.-H.; Haggarty, S.; Leung, A. K.-W.
10.1101/2020.06.18.159665 — neuroscience — Posted on 2020-06-18
2066 Chromatin potential identified by shared single cell profiling of RNA and chromatin
Ma, S.; Zhang, B.; LaFave, L.; Chiang, Z.; Hu, Y.; Ding, J.; Brack, A.; Kartha, V. K.; Law, T.; Lareau, C.; Hsu, Y.-C.; Regev, A.; Buenrostro, J. D.
10.1101/2020.06.17.156943 — genomics — Posted on 2020-06-18
2067 Genomic features of parthenogenetic animals
Jaron, K. S.; Bast, J.; Nowell, R. W.; Ranallo-Benavidez, T. R.; Robinson-Rechavi, M.; Schwander, T.
10.1101/497495 — genomics — Posted on 2020-06-18
2068 Genome-wide association study of circulating liver enzymes reveals an expanded role for manganese transporter SLC30A10 in liver health
Ward, L. D.; Tu, H.-C.; Quenneville, C.; Flynn-Carroll, A. O.; Parker, M. M.; Deaton, A. M.; Haslett, P. A. J.; Hinkle, G.; Nioi, P.
10.1101/2020.05.19.104570 — genetics — Posted on 2020-06-18
2070 The Distribution of Enset Pests and Pathogens and a Genomic Survey of Enset Xanthomonas Wilt
Yemataw, Z.; Borrell, J. S.; Biswas, M. K.; White, O.; Mengesha, W.; Muzemil, S.; Darbar, J.; Ondo, I.; Heslop-Harrison, P. S.; Blomme, G.; Wilkin, P.
10.1101/2020.06.18.144261 — ecology — Posted on 2020-06-18
2073 Skeletal Muscle Remodeling in Immobilized Patients: Determined Using a Parameter Estimation Histomorphometric Approach
Formosa, B.; Liyanaarachchi, A.; Silvers, S.; Gatti, D. L.; Larsson, L.; Arslanturk, S.; Jena, B. P.
10.1101/2020.06.17.157438 — cell biology — Posted on 2020-06-18
2074 3D-printed drug testing platform based on a 3D model of aged human skeletal muscle
Mestre, R.; Garcia, N.; Patino, T.; Guix, M.; Valerio-Santiago, M.; Alminana, N.; Sanchez, S.
10.1101/2020.06.18.158659 — bioengineering — Posted on 2020-06-18
2075 Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes
Lin, Z.; Wang, X.; Bustin, K. A.; He, L.; Suciu, R. M.; Schek, N.; Ahmadi, M.; Hu, K.; Olson, E. J.; Parsons, W. H.; Witze, E. S.; Morton, P. D.; Gregus, A. M.; Buczynski, M. W.; Matthews, M. L.
10.1101/2020.06.17.154864 — biochemistry — Posted on 2020-06-18
2077 Beyond Plug and Pray: Context Sensitivity and in silico Design of Artificial Neomycin Riboswitches
Günzel, C.; Kuehnl, F.; Arnold, K.; Findeiss, S.; Weinberg, C. E.; Stadler, P. F.; Mörl, M.
10.1101/2020.06.18.159046 — synthetic biology — Posted on 2020-06-18
2078 The genome assembly and annotation of Magnolia biondii Pamp., a phylogenetically, economically, and medicinally important ornamental tree species
Dong, S.; Liu, M.; Liu, Y.; Chen, F.; Yang, T.; Chen, L.; Zhang, X.; Guo, X.; Fang, D.; Li, L.; Deng, T.; Yao, Z.; Lang, X.; Gong, Y.; Wu, E.; Wang, Y.; Shen, Y.; Gong, X.; Liu, H.; Zhang, S.
10.1101/2020.06.17.158428 — plant biology — Posted on 2020-06-18
2079 Genome-Wide High Resolution Expression Map and Functions of Key Cell Fate Determinants Reveal the Dynamics of Crown Root Development in Rice
Garg, T.; Singh, Z.; Dwivedi, A. K.; Varapparambathu, V.; Singh, R. S.; Yadav, M.; Chandran, D.; Prasad, K.; Jain, M.; Yadav, S. R.
10.1101/2020.06.11.131565 — plant biology — Posted on 2020-06-18
2080 JNK signalling regulates antioxidant responses in neurons
Ugbode, C.; Garnham, N.; Fort-Aznar, L.; Evans, G. J. O.; Chawla, S.; Sweeney, S. T.
10.1101/2020.06.05.136622 — neuroscience — Posted on 2020-06-18
2082 Exploring the Stony Coral Tissue Loss Disease Bacterial Pathobiome
Iwanowicz, D.; Schill, W. B.; Woodley, C. M.; Bruckner, A. W.; Neely, K.; Briggs, K. M.
10.1101/2020.05.27.120469 — microbiology — Posted on 2020-06-18
2084 Divergent genetic effects for type 1 and type 2 diabetes at overlapping association signals
Inshaw, J. R.; Sidore, C.; Cucca, F.; Stefana, M. I.; Crouch, D. J. M.; McCarthy, M. I.; Mahajan, A.; Todd, J. A.
10.1101/2020.06.17.156778 — genetics — Posted on 2020-06-18
2085 Phylogenomics of Ichneumonoidea (Hymenoptera) and implications for evolution of mode of parasitism and viral endogenization
Sharanowski, B. J.; Ridenbaugh, R. D.; Piekarski, P. K.; Broad, G. R.; Burke, G. R.; Deans, A. R.; Lemmon, A. R.; Moriarty Lemmon, E.; Diehl, G. J.; Whitfield, J. B.; Hines, H. M.
10.1101/2020.06.17.157719 — evolutionary biology — Posted on 2020-06-18
2089 Chromosomally unstable tumor cells specifically require KIF18A for proliferation
Marquis, C.; Fonseca, C. L.; Wood, L.; Malaby, H. L.; Clayton, J. E.; Stumpff, J.
10.1101/2020.06.18.159327 — cell biology — Posted on 2020-06-18
2090 The failure of B cells to induce non-canonical MYD88 splice variants correlates with lymphomagenesis via sustained NF-κB signaling
Cardona Gloria, Y.; Bernhart, S. H.; Fillinger, S.; Wolz, O.-O.; Dickhöfer, S.; Admard, J.; Ossowski, S.; Nahnsen, S.; Siebert, R.; Weber, A. N.
10.1101/2020.06.18.154393 — cancer biology — Posted on 2020-06-18
2093 The mechanisms behind perivascular fluid flow
Daversin-Catty, C.; Vinje, V.; Mardal, K.-A.; Rognes, M. E.
10.1101/2020.06.17.157917 — physiology — Posted on 2020-06-18
2094 Nutritional status and fecundity are synchronised by muscular exopheresis
Turek, M.; Piechota, M.; Shanmugam, N.; Niklewicz, M.; Kowalski, K.; Chacinska, A.; Pokrzywa, W.
10.1101/2020.06.17.157230 — physiology — Posted on 2020-06-18
2096 Homeostatic Plasticity Requires Remodeling of the Homer-Shank Interactome
Heavner, W. E.; Speed, H. E.; Lautz, J. D.; Gniffke, E. P.; Immendorf, K. B.; Welsh, J. P.; Smith, S. E. P.
10.1101/2020.03.26.010314 — neuroscience — Posted on 2020-06-18
2097 Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer
Belorusova, A. Y.; Bourget, M.; Hessmann, S.; Chalhoub, S.; Kieffer, B.; Cianferani, S.; Rochel, N.
10.1101/2020.06.17.157305 — molecular biology — Posted on 2020-06-18
2102 The MRi-Share database: brain imaging in a cross-sectional cohort of 1,870 university students
Tsuchida, A.; Laurent, A.; Crivello, F.; Petit, L.; Joliot, M.; Pepe, A.; Beguedou, N.; Gueye, M.-F.; Verrecchia, V.; Nozais, V.; Zago, L.; Tzourio-Mazoyer, N.; Mellet, E.; Debette, S.; Tzourio, C.; Mazoyer, B.
10.1101/2020.06.17.154666 — neuroscience — Posted on 2020-06-18
2104 3D imaging of undissected optically cleared Anopheles stephensi mosquitoes infected with Plasmodium parasites
De Niz, M.; Kehrer, J.; Brancucci, N. M. B.; Moalli, F.; Reynaud, E. G.; Stein, J. V.; Frischknecht, F.
10.1101/682054 — microbiology — Posted on 2020-06-18
2105 Reading frame restoration at the EYS locus, and allele-specific chromosome removal after Cas9 cleavage in human embryos
Zuccaro, M. V.; Xu, J.; Mitchell, C.; Marin, D.; Zimmerman, R.; Rana, B.; Weinstein, E.; King, R. T.; Smith, M.; Tsang, S. H.; Goland, R.; Jasin, M.; Lobo, R.; Treff, N.; Egli, D.
10.1101/2020.06.17.149237 — genetics — Posted on 2020-06-18
2106 Exportin Crm1 is important for Swi6 nucleocytoplasmic shuttling and MBF transcription activation in Saccharomyces cerevisiae
Belanger, K. D.; Yewdell, W. T.; Barber, M.; Russo, A. N.; Pettit, M. A.; Damuth, E. K.; Hussain, N.; Geier, S. J.; Belanger, K. G.
10.1101/2020.06.17.155598 — cell biology — Posted on 2020-06-18
2108 Herbivore-induced activation of viral phosphatase disarms plant antiviral immunities for pathogen transmission
Zhao, P.; Wang, N.; Yao, X.; Zhu, C.; Hogenhout, S. A.; Liu, S.; Zhou, X.; Fang, R.-X.; YE, J.
10.1101/2020.06.17.158212 — microbiology — Posted on 2020-06-18
2109 Combining statistical and mechanistic models to identify the drivers of mortality within a rear-edge beech population
Petit-Cailleux, C.; Davi, H.; Lefevre, F.; Garrigue, J.; Magdalou, J.-A.; Hurson, C.; Magnanou, E.; Muratorio, S.
10.1101/645747 — ecology — Posted on 2020-06-18
2110 AL-PHA beads: bioplastic-based protease biosensors for global health applications
Kelwick, R. J. R.; Webb, A. J.; Wang, Y.; Heliot, A.; Allan, F.; Emery, A. M.; Templeton, M. R.; Freemont, P. S.
10.1101/2020.06.18.159921 — synthetic biology — Posted on 2020-06-18
2115 WNT inhibition creates a BRCA-like state in Wnt-addicted cancer
Kaur, A.; Sepramaniam, S.; Lim, J. Y. S.; Patnaik, S.; HARMSTON, N. P.; Lee, M. A.; Petretto, E. G.; Virshup, D.; Madan, B.
10.1101/2020.06.17.157024 — cancer biology — Posted on 2020-06-18
2116 ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer
Trincado, J. L.; Reixachs-Sole, M.; Fugmann, T.; Yokota, J.; Eyras, E.
10.1101/2020.06.18.159244 — bioinformatics — Posted on 2020-06-18
2121 Structural basis for phosphorylation independent activation of c-CBLby Src-like adaptor protein 2.
Wybenga-Groot, L. E.; Tench, A. J.; Simpson, C. D.; St. Germain, J.; Raught, B.; Moran, M. F.; McGlade, C. J.
10.1101/2020.06.18.159806 — molecular biology — Posted on 2020-06-18
2122 Single cell landscape of hypertrophic scars identifies serine proteases as key regulators of myofibroblast differentiation
Vorstandlechner, V.; Laggner, M.; Copic, D.; Chen, Y.; Golabi, B.; Haslik, W.; Radtke, C.; Tschachler, E.; Ankersmit, H. J.; Mildner, M.
10.1101/2020.06.17.157073 — cell biology — Posted on 2020-06-18
2127 Quantifying the acquisition and retention of lumpy skin disease virus by haematophagus insects and the implications for transmission and control.
Sanz-Bernardo, B.; Haga, I. R.; Wijesiriwardana, N.; Basu, S.; Larner, W.; Diaz, A. V.; Langlands, Z.; Denison, E.; Stoner, J.; White, M.; Sanders, C.; Hawes, P. C.; Wilson, A. J.; Atkinson, J.; Batten, C.; Alphey, L.; Darpel, K. E.; Gubbins, S.; Beard, P. M.
10.1101/2020.06.18.154252 — microbiology — Posted on 2020-06-18
2129 Accessory ESCRT-III proteins selectively regulate Rab11-exosome biogenesis in Drosophila secondary cells
Marie, P.; Fan, S.-J.; Mendes, C. C.; Wainwright, M.; Harris, A. L.; Goberdhan, D.; Wilson, C.
10.1101/2020.06.18.158725 — cell biology — Posted on 2020-06-18
2132 Bcr-Abl tyrosine kinase inhibitor imatinib as a potential drug for COVID-19
Mulgaonkar, N. S.; Wang, H.; Mallawarachchi, S.; Ruzek, D.; Martina, B.; Fernando, S.
10.1101/2020.06.18.158196 — microbiology — Posted on 2020-06-18
2134 Early temporal dynamics of cellular responses to SARS-CoV-2
Banerjee, A.; Budylowski, P.; Richard, D.; Maan, H.; Aguiar, J.; El-Sayes, N.; D'Agostino, M. R.; Tremblay, B. J.- M.; Afkhami, S.; Karimzadeh, M.; Yip, L.; Ostrowski, M. A.; Hirota, J. A.; Kozak, R.; Capellini, T. D.; Miller, M. S.; McArthur, A. G.; Wang, B.; Doxey, A. C.; Mubareka, S.; Mossman, K.
10.1101/2020.06.18.158154 — immunology — Posted on 2020-06-18
2135 Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs
Kern, D. M.; Sorum, B.; Hoel, C. M.; Sridharan, S.; Remis, J. P.; Toso, D. B.; Brohawn, S. G.
10.1101/2020.06.17.156554 — biophysics — Posted on 2020-06-18
2137 Divergent SARS-CoV-2-specific T and B cell responses in severe but not mild COVID-19
Oja, A. E.; Saris, A.; Ghandour, C. A.; Kragten, N. A. M.; Hogema, B. M.; Nossent, E. J.; Heunks, L. M. A.; Cuvalay, S.; Slot, E.; Swaneveld, F. H.; Vrielink, H.; Rispens, T.; van der Schoot, E.; van Lier, R. A. W.; Ten Brinke, A.; Hombrink, P.
10.1101/2020.06.18.159202 — immunology — Posted on 2020-06-18
2138 Genomic surveillance of SARS-CoV-2 reveals community transmission of a major lineage during the early pandemic phase in Brazil
Resende, P. C.; Delatorre, E.; Graf, T.; Mir, D.; Motta, F. C.; Appolinario, L.; Paixao, A. C. D.; Ogrzewalska, M.; Caetano, B.; Santos, M. C.; Ferreira, J. A.; Souza Junior, E. C.; Silva, S. P.; Fernandes, S. B.; Vianna, L. A.; Costa, L.; Ferro, J.; Nardy, V.; Croda, J.; Oliveira, W. K.; Abreu, A. L. d.; Bello, G.; Siqueira, M. M.
10.1101/2020.06.17.158006 — evolutionary biology — Posted on 2020-06-18
2140 A previously uncharacterized gene in SARS-CoV-2 and the origins of the COVID-19 pandemic
Nelson, C. W.; Ardern, Z.; Goldberg, T. L.; Meng, C.; Kuo, C.-H.; Ludwig, C.; Kolokotronis, S.-O.; Wei, X.
10.1101/2020.05.21.109280 — evolutionary biology — Posted on 2020-06-18
2141 Unexpected free fatty acid binding pocket in the cryo-EM structure of SARS-CoV-2 spike protein
Toelzer, C.; Gupta, K.; Yadav, S. K.; Borucu, U.; Garzoni, F.; Staufer, O.; Capin, J.; Spatz, J.; Fitzgerald, D.; Berger, I.; Schaffitzel, C.
10.1101/2020.06.18.158584 — biochemistry — Posted on 2020-06-18
2142 The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins
Conceicao, C.; Thakur, N.; Human, S.; Kelly, J. T.; Logan, L.; Bialy, D.; Bhat, S.; Stevenson-Leggett, P.; Zagrajek, A.; Hollinghurst, P.; Varga, M.; Tsirigoti, C.; Hammond, J.; Maier, H. J.; Bickerton, E.; Shelton, H. J.; Dietrich, I.; Graham, S. C.; Bailey, D.
10.1101/2020.06.17.156471 — microbiology — Posted on 2020-06-18
2143 The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
Cubuk, J.; Alston, J. J.; Incicco, J. J.; Singh, S.; Stuchell-Brereton, M. D.; Ward, M. D.; Zimmerman, M. I.; Vithani, N.; Griffith, D.; Wagoner, J. A.; Bowman, G. R.; Hall, K. B.; Soranno, A.; Holehouse, A. S.
10.1101/2020.06.17.158121 — biophysics — Posted on 2020-06-18
2144 Potent Neutralizing Monoclonal Antibodies Directed to Multiple Epitopes on the SARS-CoV-2 Spike
Ho, D. D.; Lihong, L.; Wang, P.; Nair, M. S.; Jian, Y.; Huang, Y.; Rapp, M. A.; Wang, Q.; Luo, Y.; Sahi, V.; Figueroa, A.; Guo, X. V.; Cerutti, G.; Bimela, J.; Gorman, J.; Zhou, T.; Kwong, P. D.; G. Sodroski, J. G.; Yin, M. T.; Sheng, Z.; Shapiro, L.
10.1101/2020.06.17.153486 — microbiology — Posted on 2020-06-18
2145 Saliva-Based Molecular Testing for SARS-CoV-2 that Bypasses RNA Extraction
Ranoa, D.; Holland, R.; Alnaji, F. G.; Green, K.; Wang, L.; Brooke, C.; Burke, M.; Fan, T.; Hergenrother, P. J.
10.1101/2020.06.18.159434 — microbiology — Posted on 2020-06-18
2146 Functional connectivity changes with rapid remission from severe major depressive disorder
Xiao, X.; Bentzley, B.; Cole, E. J.; Tischler, C.; Stimpson, K. H.; Duvio, D.; Bishop, J. H.; DeSouza, D. D.; Schatzberg, A.; Keller, C.; Sudheimer, K.; Williams, N. R.
10.1101/672154 — clinical trials — Posted on 2020-06-18
2149 Premature commitment to uncertain beliefs during human NMDA receptor hypofunction
Salvador, A.; Arnal, L. H.; Vinckier, F.; Domenech, P.; Gaillard, R.; Wyart, V.
10.1101/2020.06.17.156539 — neuroscience — Posted on 2020-06-18
2150 Ultra-pure isolation of low density neutrophils casts doubt on their exceptionality in health and disease
Hardisty, G. R.; Llanwarne, F.; Minns, D.; Gillan, J. L.; Davidson, D. J.; Gwyer Findlay, E. R.; Gray, R. D.
10.1101/2020.06.17.156588 — immunology — Posted on 2020-06-18
2154 Adaptive mechanoproperties characterize glioblastoma fitness for invasion
Monzo, P.; Crestani, M.; Chong, Y. K.; Hennig, K.; Ghisleni, A.; Li, Q.; Richichi, C.; Maiuri, P.; Balland, M.; Sheetz, M. P.; Pelicci, G.; Ang, B. T.; Tang, C.; Gauthier, N. C.
10.1101/2020.06.17.156406 — cell biology — Posted on 2020-06-18
2156 Unsupervised Neural Network Models of the Ventral Visual Stream
Zhuang, C.; Yan, S.; Nayebi, A.; Schrimpf, M.; Frank, M.; DiCarlo, J.; Yamins, D.
10.1101/2020.06.16.155556 — neuroscience — Posted on 2020-06-18
2159 Longitudinal Saliva Omics Responses to Immune Perturbation: A Case Study
Mias, G. I.; Singh, V. V.; Rogers, L. R.; Xue, S.; Zheng, M.; Domanskyi, S.; Kanada, M.; Piermarocchi, C.; He, J.
10.1101/2020.06.16.156133 — genomics — Posted on 2020-06-18
2160 High-order mutants reveal an essential requirement for peroxidases but not laccases in Casparian strip lignification
Rojas-Murcia, N.; Hematy, K.; Lee, Y.; Emonet, A.; Ursache, R.; Fujita, S.; De Bellis, D.; Geldner, N.
10.1101/2020.06.17.154617 — plant biology — Posted on 2020-06-18
2164 The Amsterdam Open MRI Collection, a set ofmultimodal MRI datasets for individual differenceanalyses
Snoek, L.; van der Miesen, M.; Beemsterboer, T.; van der Leij, A.; Eigenhuis, A.; Scholte, H. S.
10.1101/2020.06.16.155317 — neuroscience — Posted on 2020-06-18
2166 BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance.
Donoghue, L. J.; Markovetz, M. R.; Morrison, C. B.; McFadden, K. M.; Rogers, T. D.; Button, B.; Ehre, C.; Hill, D. B.; Grubb, B. R.; Kelada, S. N. P.
10.1101/2020.06.17.155846 — physiology — Posted on 2020-06-18
2173 COVID-19 PCR Test Performance For Samples Stored At Ambient Temperature
Agaoglu, N. B.; Yıldız, J.; Akgun Dogan, O.; Alkurt, G.; Kose, B.; Kendir Demirkol, Y.; Irvem, A.; Doganay, L.; Dinler-Doganay, G.
10.1101/2020.06.15.153882 — microbiology — Posted on 2020-06-18
2175 Genomic balancing selection is key to the invasive success of the fall armyworm
Yainna, S.; Tay, W. T.; Fiteni, E.; Legeai, F.; Clamens, A.-L.; Gimenez, S.; Frayssinet, M.; Asokan, R.; Kalleshwaraswamy, C.; Deshmukh, S.; Meagher, R. L.; Blanco, C. A.; Silvie, P.; Brevault, T.; Dassou, A.; Kergoat, G. J.; Walsh, T.; Gordon, K.; Negre, N.; d'Alencon, E.; Nam, K.
10.1101/2020.06.17.154880 — evolutionary biology — Posted on 2020-06-18
2177 Oral administration of a single anti-CfaE nanobody provides broadly cross-protective immunity against major pathogenic Enterotoxigenic Escherichia coli strains
Amcheslavsky, A.; Wallace, A.; Ejemel, M.; Li, Q.; McMahon, C.; Stoppato, M.; Giuntini, S.; Schiller, Z. A.; Pondish, J.; Toomey, J. R.; Schneider, R.; Meisinger, J.; Heukers, R.; Kruse, A. C.; Barry, E. M.; Pierce, B.; Klempner, M. S.; Cavacini, L. A.; Wang, Y.
10.1101/2020.06.16.155465 — microbiology — Posted on 2020-06-18
2180 Ghrelin signaling regulates feeding behavior, metabolism, and memory through the vagus nerve
Davis, E. A.; Wald, H. S.; Suarez, A. N.; Zubcevic, J.; Liu, C. M.; Cortella, A. M.; Kamitakahara, A. K.; Polson, J. W.; Arnold, M.; Grill, H. J.; de Lartigue, G.; Kanoski, S. E.
10.1101/2020.06.16.155762 — neuroscience — Posted on 2020-06-18
2181 Loss of O-GlcNAcylation on MeCP2 Thr 203 Leads to Neurodevelopmental Disorders
Cheng, J.; Zhao, Z.; Chen, L.; Du, R.; Wu, Y.; Zhu, Q.; Fan, M.; Duan, X.; Wu, H.
10.1101/2020.06.17.158311 — neuroscience — Posted on 2020-06-18
2184 Trophic cooperation promotes bacterial survival of Staphylococcus aureus and Pseudomonas aeruginosa
Camus, L.; Briaud, P.; Bastien, S.; Elsen, S.; Doleans-Jordheim, A.; Vandenesch, F.; Moreau, K.
10.1101/2020.06.17.156968 — microbiology — Posted on 2020-06-18
2186 Environmental and physiological factors affecting high-throughput measurements of bacterial growth
Atolia, E.; Cesar, S.; Arjes, H.; Rajendram, M.; Shi, H.; Knapp, B.; Khare, S.; Aranda-Diaz, A.; Lenski, R.; Huang, K. C.
10.1101/2020.06.16.156182 — microbiology — Posted on 2020-06-18
2187 High fat diet disrupts diurnal interactions between REG3g and small intestinal gut microbes resulting in metabolic dysfunction
Frazier, K.; Kambal, A.; Zale, E. A.; Pierre, J. F.; Hubert, N.; Miyoshi, S.; Miyoshi, J.; Ringus, D.; Harris, D.; Yang, K.; Cham, C.; Musch, M. W.; Chang, E. B.; Leone, V.
10.1101/2020.06.17.130393 — microbiology — Posted on 2020-06-18
2190 Cortical microinfarcts potentiate recurrent ischemic injury through NLRP3-dependent trained immunity
Feng, Y.; Wu, T.; Feng, Y.; Liang, F.; Li, G.; Li, Y.; Guan, Y.; Liu, S.; Zhang, Y.; Xu, G.; Zhong, P.
10.1101/2020.06.17.157289 — immunology — Posted on 2020-06-18
2191 Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8
Gong, Q.; Robinson, K.; Xu, C.; Zhang, J.; Boo, Z. Z.; Teo, D. E. T.; Zhang, Y.; Lim, J. S. Y.; Goh, W. I.; Wright, G.; Zhong, F. L.; Wu, B.; Reversade, B.
10.1101/2020.06.17.156307 — immunology — Posted on 2020-06-18
2192 Baseline and Innate Immune Response Characterization of a Zfp30 Knockout Mouse Strain
Laudermilk, L. T.; Tovar, A.; Homstad, A. K.; Thomas, J. M.; McFadden, K. M.; Tune, M. K.; Cowley, D. O.; Mock, J. R.; Ideraabdullah, F. Y.; Kelada, S. N.
10.1101/2020.06.17.154526 — genetics — Posted on 2020-06-18
2193 Satellite virus diversification through host shifting revealed by novel deltaviruses in vampire bats
Bergner, L.; Orton, R.; Broos, A.; Tello, C.; Becker, D.; Carrera, J.; Patel, A.; Biek, R.; Streicker, D.
10.1101/2020.06.17.156745 — evolutionary biology — Posted on 2020-06-18
2194 Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs
Maeda, T.; Takahashi, S.; Yoshida, T.; Shimamura, S.; Takaki, Y.; Nagai, Y.; Toyoda, A.; Suzuki, Y.; Arimoto, A.; Ishii, H.; Satoh, N.; Nishiyama, T.; Hasebe, M.; Maruyama, T.; Minagawa, J.; Obokata, J.; Shigenobu, S.
10.1101/2020.06.16.155838 — evolutionary biology — Posted on 2020-06-18
2195 Probabilistic programming: a powerful new approach to statistical phylogenetics
Ronquist, F.; Kudlicka, J.; Senderov, V.; Borgström, J.; Lartillot, N.; Lunden, D.; Murray, L.; Schön, T. B.; Broman, D.
10.1101/2020.06.16.154443 — evolutionary biology — Posted on 2020-06-18
2198 The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma
Ponnusamy, K.; Tzioni, M. M.; Begum, M.; Robinson, M. E.; Caputo, V. S.; Katsarou, A.; Trasanidis, N.; Xiao, X.; Kostopoulos, I. V.; Iskander, D.; Roberts, I.; Trivedi, P.; Auner, H. W.; Naresh, K.; Chaidos, A.; Karadimitris, A.
10.1101/2020.06.17.157107 — cancer biology — Posted on 2020-06-18
2200 CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signalling to promote expansion of cortical progenitors.
van Heurck, R.; Wojno, M.; Suzuki, I.; Velez, F.; Bonnefont, J.; Erkol, E.; Nguyen, D. T.; Herpoel, A.; Bilheu, A.; Ledent, C.; Vanderhaeghen, P.
10.1101/2020.06.17.142976 — neuroscience — Posted on 2020-06-18
2201 Tbr2-expressing retinal ganglion cells are ipRGCs
Mao, C.-A.; Chen, C.-K.; Kiyama, T.; Weber, N.; Whitaker, C. M.; Pan, P.; Badea, T. C.; Massey, S. C.
10.1101/2020.06.17.153551 — neuroscience — Posted on 2020-06-18
2203 Characterization of basal forebrain glutamate neurons suggests a role in control of arousal and avoidance behavior
McKenna, J. T.; Yang, C.; Bellio, T.; Anderson-Chernishof, M. B.; Gamble, M. C.; Hulverson, A.; McCoy, J. G.; Winston, S.; McNally, J. M.; Basheer, R.; Brown, R. E.
10.1101/2020.06.17.157479 — neuroscience — Posted on 2020-06-18
2204 A general theory of coherence between brain areas
Schneider, M.; Dann, B.; Sheshadri, S.; Scherberger, H. G.; Vinck, M.
10.1101/2020.06.17.156190 — neuroscience — Posted on 2020-06-18
2206 The gut microbiome regulates memory function
Noble, E. E.; Davis, E. A.; Tsan, L.; Chen, Y.-W.; Olson, C.; Schade, R.; Liu, C.; Suarez, A. N.; Jones, R. B.; Goran, M. I.; de La Serre, C.; Yang, X.; Hsiao, E. Y.; Kanoski, S.
10.1101/2020.06.16.153809 — neuroscience — Posted on 2020-06-18
2207 Developing human fetal skin demonstrates a unique lymphocyte signature
Dhariwala, M. O.; Karthikeyan, D.; Vasquez, K. S.; Farhat, S.; Taravati, K.; Leitner, E. G.; Pauli, M.; Lowe, M. M.; Rosenblum, M. D.; Scharschmidt, T. C.
10.1101/2020.06.16.153593 — immunology — Posted on 2020-06-18
2208 Single cell transcriptomic profiling identifies molecular phenotypes of newborn human lung cells
Bhattacharya, S.; Myers, J.; Baker, C.; Guo, M.; Danopoulos, S.; Myers, J.; Bandopadhyay, G.; Romas, S.; Huyck, H. L.; Misra, R. S.; Dutra, J.; Holden-Wiltse, J.; McDavid, A.; Ashton, J.; Al Alam, D.; Potter, S.; Whitsett, J. A.; Xu, Y.; Pryhuber, G. S.; Mariani, T. J.
10.1101/2020.06.16.156042 — genomics — Posted on 2020-06-18
2210 Mutation bias shapes gene evolution in Arabidopsis thaliana
Monroe, J. G.; Srikant, T.; Carbonell-Bejerano, P.; Exposito-Alonso, M.; Weng, M.-L.; Rutter, M. T.; Fenster, C. B.; Weigel, D.
10.1101/2020.06.17.156752 — evolutionary biology — Posted on 2020-06-18
2216 Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Wang, Y.; Brodin, E.; Nishii, K.; Frieboes, H. B.; Mumenthaler, S.; Sparks, J. L.; Macklin, P.
10.1101/2020.05.04.074989 — systems biology — Posted on 2020-06-18
2217 Tactile active sensing in insect-plant pollination
Deora, T.; Ahmed, M. A.; Daniel, T. L.; Brunton, B. W.
10.1101/2020.06.16.155507 — neuroscience — Posted on 2020-06-17
2218 Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence
Scott, J.; Sueiro-Olivares, M.; Thornton, B. P.; Owens, R. A.; Muhamadali, H.; Fortune-Grant, R.; Thomas, R.; Hollywood, K.; Doyle, S.; Goodacre, R.; Tabernero, L.; Bignell, E.; Amich, J.
10.1101/2020.06.04.131862 — microbiology — Posted on 2020-06-17
2220 Effects of date fruit (Phoenix dactylifera) on sperm cell morphology and reproductive hormonal profiles in cypermethrin-induced male infertility
Ubah, S. A.; Agbonu, O. A.; Kwinjoh, C. P.; Abah, K. O.; Chibuogwu, I. C.; Abalaka, S. E.; Bankole, A. S.; Enem, S. I.; Ejiofor, C. E.; Ajayi, I. E.
10.1101/2020.06.17.156687 — pharmacology and toxicology — Posted on 2020-06-17
2223 Common genetic variation influencing human white matter microstructure
Zhao, B.; Li, T.; Yang, Y.; Wang, X.; Luo, T.; Shan, Y.; Zhu, Z.; Xiong, D.; Hauberg, M. E.; Bendl, J.; Fullard, J. F.; Roussos, P.; Li, Y.; Stein, J. L.; Zhu, H.
10.1101/2020.05.23.112409 — genetics — Posted on 2020-06-17
2224 Genome-scale genetic screening identifies PRMT1 as a critical vulnerability in castration-resistant prostate cancer
Tang, S.; Metaferia, N. Y.; Nogueira, M. F.; Gelbard, M. K.; Abou Alaiwi, S.; Seo, J.-H.; Hwang, J. H.; Strathdee, C. A.; Baca, S. C.; Li, J.; AbuHammad, S.; Zhang, X.; Doench, J. G.; Hahn, W. C.; Takeda, D. Y.; Freedman, M. L.; Choi, P. S.; Viswanathan, S. R.
10.1101/2020.06.17.156034 — cancer biology — Posted on 2020-06-17
2225 An Integrative Genetic, Epigenetic and Proteomic Characterization of Pancreatic Neuroendocrine Neoplasms (PanNENs) defines Distinct Molecular Features of α- and β-cell like Subgroups
Simon, T.; Mamlouk, S.; Riemer, P.; Bormann, F.; Klinger, B.; Menne, A.; Teichmann, D.; Wanke-Moehr, K.; Pacyna-Gengelbach, M.; Khouja, S.; Lenze, D.; Capper, D.; Ruoff, F.; Templin, M.; Leser, U.; Detjen, K.; Rossner, F.; Haybaeck, J.; Morkel, M.; Bluethgen, N.; Horst, D.; Pavel, M.; Sers, C.
10.1101/2020.06.12.146811 — cancer biology — Posted on 2020-06-17
2226 Light-activated signaling in DNA-encoded sender-receiver architectures
Yang, S.; Pieters, P.; Joesaar, A.; Bogels, B.; Brouwers, R.; Myrgorodska, I.; Mann, S.; de Greef, T.
10.1101/2020.06.10.144162 — synthetic biology — Posted on 2020-06-17
2228 Extensive individual differences of category information in ventral temporal cortex in the congenitally blind
Rosenke, M.; van den Hurk, J.; Margalit, E.; Op de Beeck, H. P.; grill-spector, k.; Weiner, K. S.
10.1101/2020.06.14.151092 — neuroscience — Posted on 2020-06-17
2229 Transposable element mobilization in interspecific yeast hybrids
Smukowski Heil, C.; Patterson, K.; Hickey, A. S.-M.; Alcantara, E.; Dunham, M. J.
10.1101/2020.06.16.155218 — genetics — Posted on 2020-06-17
2230 The changing mouse embryo transcriptome at whole tissue and single-cell resolution
He, P.; Williams, B. A.; Trout, D.; Marinov, G. K.; Amrhein, H.; Berghella, L.; Goh, S.-T.; Plajzer-Frick, I.; Afzal, V.; Pennacchio, L. A.; Dickel, D. E.; Visel, A.; Ren, B.; Hardison, R. C.; Zhang, Y.; Wold, B. J.
10.1101/2020.06.14.150599 — developmental biology — Posted on 2020-06-17
2233 DeepEMhancer: a deep learning solution for cryo-EM volume post-processing
Sanchez Garcia, R.; Gomez-Blanco, J.; Cuervo, A.; Carazo, J. M.; Sorzano, C. O. S.; Vargas, J.
10.1101/2020.06.12.148296 — bioinformatics — Posted on 2020-06-17
2234 Multi-level proteomics reveals host-perturbation strategies of SARS-CoV-2 and SARS-CoV
Stukalov, A.; Girault, V.; Grass, V.; Bergant, V.; Karayel, O.; Urban, C.; Haas, D. A.; Huang, Y.; Oubraham, L.; Wang, A.; Hamad, S. M.; Piras, A.; Tanzer, M.; Hansen, F. M.; Engleitner, T.; Reinecke, M.; Lavacca, T. M.; Ehmann, R.; Wölfel, R.; Jores, J.; Küster, B.; Protzer, U.; Rad, R.; Ziebuhr, J.; Thiel, V.; Scaturro, P.; Mann, M.; Pichlmair, A.
10.1101/2020.06.17.156455 — systems biology — Posted on 2020-06-17
2237 Improved neurocognitive performance in FIV infected cats following treatment with the p75 neurotrophin receptor ligand LM11A-31
Fogle, J. E.; Hudson, L.; Thompson, A.; Sherman, B.; Gruen, M.; Lacelles, B. D.; Colby, B. M.; Clary, G.; Longo, F.; Meeker, R.
10.1101/2020.06.17.156596 — neuroscience — Posted on 2020-06-17
2240 A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
Kroll, F.; Powell, G. T.; Ghosh, M.; Antinucci, P.; Hearn, T. J.; Tunbak, H.; Lim, S.; Dennis, H. W.; Fernandez, J. M.; Hoffman, E. J.; Whitmore, D.; Dreosti, E.; Wilson, S. W.; Rihel, J.
10.1101/2020.06.04.133462 — genetics — Posted on 2020-06-17
2242 De novo genome assembly and transcriptome analysis for the drought and salt resistant Solanum sitiens
Molitor, C.; Kurowski, T. J.; Fidalgo de Almeida, P. M.; Eerolla, P.; Spindlow, D. J.; Kashyap, S. P.; Singh, B.; Prasanna, H. C.; Thompson, A. J.; Mohareb, F. R.
10.1101/2020.06.14.151043 — bioinformatics — Posted on 2020-06-17
2243 High-Accuracy Multiplexed SARS-CoV-2 Antibody Assay with Avidity and Saliva Capability on a Nano-Plasmonic Platform
Liu, T.; Hsiung, J.; Zhao, S.; Kost, J.; Sreedhar, D.; Olson, K.; Keare, D.; Roche, J.; Hanson, C. V.; Press, C.; Boggs, J.; Rodriguez-Soto, J. P.; Montoya, J. G.; Tang, M.; Dai, H.
10.1101/2020.06.16.155580 — biochemistry — Posted on 2020-06-17
2247 Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration
Temisak, S.; Thangsunan, P.; Boonil, J.; Yenchum, W.; Hongthong, K.; Yata, T.; Solis, L. R.; Morris, P.
10.1101/2020.06.14.150375 — molecular biology — Posted on 2020-06-17
2248 Holder Pasteurization Inactivates SARS-CoV-2 in Human Breast Milk
Conzelmann, C.; Gross, R.; Meister, T. L.; Todt, D.; Krawczyk, A.; Dittmer, U.; Stenger, S.; Muench, J.; Steinmann, E.; Mueller, J. A.; Pfaender, S.
10.1101/2020.06.17.155689 — microbiology — Posted on 2020-06-17
2250 Reconstitution of Alveolar Regeneration via novel DATPs by Inflammatory Niches
Choi, J.; Park, J.-E.; Tsagkogeorga, G.; Yanagita, M.; Koo, B.-K.; Han, N.; Lee, J.-H.
10.1101/2020.06.14.151324 — cell biology — Posted on 2020-06-17
2251 Crystal structure of SARS-CoV-2 main protease in complex with a Chinese herb inhibitor shikonin
Li, J.; Zhou, X.; Zhang, Y.; Zhong, F.; Lin, C.; McCormick, P. J.; Jiang, F.; Zhou, H.; Wang, Q.; Duan, J.; Zhang, J.
10.1101/2020.06.16.155812 — biophysics — Posted on 2020-06-17
2254 A validation scale to determine the readiness of environmental DNA assays for routine species monitoring
Thalinger, B.; Deiner, K.; Harper, L. R.; Rees, H. C.; Blackman, R. C.; Sint, D.; Traugott, M.; Goldberg, C. S.; Bruce, K.
10.1101/2020.04.27.063990 — molecular biology — Posted on 2020-06-17
2255 Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection
Wei, J.; Alfajaro, M.; Hanna, R.; DeWeirdt, P.; Strine, M.; Lu-Culligan, W.; Zhang, S.-M.; Graziano, V.; Schmitz, C.; Chen, J.; Mankowski, M.; Filler, R.; Gasque, V.; de Miguel, F.; Chen, H.; Oguntuyo, K. Y.; Abriola, L.; Surovtseva, Y.; Orchard, R.; Lee, B.; Lindenbach, B.; Politi, K.; van Dijk, D.; Simon, M.; Yan, Q.; Doench, J. G.; Wilen, C. B.
10.1101/2020.06.16.155101 — genetics — Posted on 2020-06-17
2256 Prediction of complex phenotypes using the Drosophila metabolome
Rohde, P. D.; Kristensen, T. N.; Sarup, P.; Munoz, J.; Malmendal, A.
10.1101/2020.06.11.145623 — genetics — Posted on 2020-06-17
2260 SCIM: Universal Single-Cell Matching with Unpaired Feature Sets
Stark, S. G.; Ficek, J.; Locatello, F.; Bonilla, X.; Chevrier, S.; Singer, F.; Tumor Profiler Consortium, ; Rätsch, G.; Lehmann, K.
10.1101/2020.06.11.146845 — bioinformatics — Posted on 2020-06-17
2261 A thermostable, closed, SARS-CoV-2 spike protein trimer.
Xiong, X.; Qu, K.; Ciazynska, K. A.; Hosmillo, M.; Carter, A. P.; Ebrahimi, S.; Ke, Z.; Scheres, S. H. W.; Bergamaschi, L.; Grice, G. L.; Zhang, Y.; The CITIID-NIHR COVID-19 BioResource Collaboration, ; Nathan, J. A.; Baker, S.; James, L. C.; Baxendale, H. E.; Goodfellow, I.; Doffinger, R.; Briggs, J. A. G.
10.1101/2020.06.15.152835 — biochemistry — Posted on 2020-06-17
2272 Processive activity of the replicative DNA polymerases in the replisome of live eukaryotic cells
Kapadia, N.; El-Hajj, Z. W.; Zheng, H.; Beattie, T. R.; Yu, A.; REYES LAMOTHE, R.
10.1101/780270 — molecular biology — Posted on 2020-06-17
2276 Detection of SARS-CoV-2 RNA by multiplex RT-qPCR
Kudo, E.; Israelow, B.; Vogels, C.; Lu, P.; Wyllie, A. L.; Tokuyama, M.; Venkataraman, A.; Brackney, D. E.; Ott, I.; Petrone, M.; Earnest, R.; Lapidus, S.; Muenker, C.; Moore, A.; Casanovas-Massana, A.; Yale IMPACT Research Team, ; Omer, S.; Dela Cruz, C.; Farhadian, S.; Ko, A.; Grubaugh, N.; Iwasaki, A.
10.1101/2020.06.16.155887 — microbiology — Posted on 2020-06-17
2277 JARA: 'Just Another Red-List Assessment'
Winker, H.; Pacoureau, N.; Sherley, R. B.
10.1101/672899 — ecology — Posted on 2020-06-17
2278 Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
Starr, T. N.; Greaney, A. J.; Hilton, S. K.; Crawford, K. H.; Navarro, M. J.; Bowen, J. E.; Tortorici, M. A.; Walls, A. C.; Veesler, D.; Bloom, J. D.
10.1101/2020.06.17.157982 — microbiology — Posted on 2020-06-17
2282 Controlling protein nanocage assembly with hydrostatic pressure
Le Vay, K. K.; Carter, B. M.; Watkins, D. W.; Tang, T.-Y. D.; Ting, V. P.; Rambo, R. P.; Smith, A. J.; Anderson, J. L. R.; Perriman, A. W.
10.1101/2020.06.16.154534 — biophysics — Posted on 2020-06-17
2285 Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014
Huong, N. Q.; Nga, N. T. T.; Long, N. V.; Luu, B. D.; Latinne, A.; Pruvot, M.; Phuong, N. T.; Quang, L. T. V.; Hung, V. V.; Lan, N. T.; Hoa, N. T.; Minh, P. Q.; Diep, N. T.; Tung, N.; Ky, V. D.; Roberton, S. I.; Thuy, H. B.; Long, N. V.; Gilbert, M.; Wicker, L.; Mazet, J. A. K.; Johnson, C. K.; Goldstein, T.; Tremeau-Bravard, A.; Ontiveros, V.; Joly, D. O.; Walzer, C.; Fine, A. E.; Olson, S. H.
10.1101/2020.06.05.098590 — microbiology — Posted on 2020-06-17
2287 Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD
Zhang, G.; Pomplun, S.; Loftis, A. R.; Tan, X.; Loas, A.; Pentelute, B. L.
10.1101/2020.03.19.999318 — bioengineering — Posted on 2020-06-17
2288 Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis
Herrera, N. G.; Morano, N. C.; Celikgil, A.; Georgiev, G. I.; Malonis, R. J.; Lee, J. H.; Tong, K.; Vergnolle, O.; Massimi, A. B.; Yen, L. Y.; Noble, A. J.; Kopylov, M.; Bonanno, J. B.; Garrett-Thomson, S. C.; Hayes, D. B.; Bortz, R. H.; Wirchniaski, A. S.; Florez, C.; Laudermilch, E.; Haslwanter, D.; Fels, J. M.; Dieterle, M. E.; Jangra, R. K.; Barnhill, J.; Mengotto, A.; Kimmel, D.; Daily, J. P.; Pirofski, L.-a.; Chandran, K.; Brenowitz, M.; Garforth, S. J.; Eng, E. T.; Lai, J. R.; Almo, S. C.
10.1101/2020.06.14.150607 — biochemistry — Posted on 2020-06-17
2289 Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane
Woo, H.; Park, S.-J.; Choi, Y. K.; Park, T.; Tanveer, M.; Cao, Y.; Kern, N. R.; Lee, J.; Yeom, M. S.; Croll, T. I.; Seok, C.; Im, W.
10.1101/2020.05.20.103325 — biophysics — Posted on 2020-06-17
2290 Overhauling a faulty control in the CDC-recommended SARS-CoV-2 RT-PCR test panel
Dekker, R. J.; Ensink, W. A.; van Leeuwen, S.; Rauwerda, H.; Breit, T. M.
10.1101/2020.06.12.147819 — microbiology — Posted on 2020-06-17
2291 Expansion of SARS-CoV-2-specific Antibody-secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients
Varnaite, R.; Garcia, M.; Glans, H.; Maleki, K. T.; Sandberg, J. T.; Tynell, J.; Christ, W.; Lagerqvist, N.; Asgeirsson, H.; Ljunggren, H.-G.; Ahlen, G.; Frelin, L.; Sällberg, M.; Blom, K.; Klingström, J.; Gredmark-Russ, S.
10.1101/2020.05.28.118729 — immunology — Posted on 2020-06-17
2292 Genomic surveillance and phylogenetic analysis reveal multiple introductions of SARS-CoV-2 into a global travel hub in the Middle East
Abou Tayoun, A.; Loney, T.; Khansaheb, H.; Ramaswamy, S.; Harilal, D.; Deesi, Z.; Varghese, R.; Al Suwaidi, H.; Alkhajeh, A.; AlDabal, L.; Uddin, M.; Senok, A.; Hamoudi, R.; Halwani, R.; Hamid, Q.; Nowotny, N.; Alsheikh-Ali, A.
10.1101/2020.05.06.080606 — genomics — Posted on 2020-06-17
2293 Bridging scales in scattering tissues via multifocal two-photon microscopy
Chen, D.; Segovia-Miranda, F.; Walker, N.; Valenzuela, J. I.; Zerial, M.; Myers, E. W.
10.1101/2020.06.11.146704 — bioengineering — Posted on 2020-06-17
2298 Interpretation of the morphological adaptations associated with viviparity in the Tsetse fly (Glossina morsitans) by three dimensional analysis.
Attardo, G. M.; Tam, N. B.; Parkinson, D. Y.; Mack, L. K.; Zahnle, X. J.; Arguellez, J.; Takac, P.; Malacrida, A. R.
10.1101/2020.06.12.147587 — physiology — Posted on 2020-06-17
2301 Bacteria- and temperature-regulated peptides modulate beta-catenin signaling in Hydra
Taubenheim, J.; Willoweit-Ohl, D.; Knop, M.; Franzenburg, S.; He, J.; Bosch, T. C. G.; Fraune, S.
10.1101/747303 — developmental biology — Posted on 2020-06-17
2303 Network-based metrics of resilience and ecological memory in lake ecosystems
Armstrong McKay, D. I.; Dyke, J. G.; Doncaster, C. P.; Dearing, J. A.; Wang, R.
10.1101/810762 — ecology — Posted on 2020-06-17
2304 Estrogen withdrawal alters oxytocin signaling in the paraventricular hypothalamus and dorsal raphe nucleus to increase postpartum anxiety
Hedges, V. L.; Heaton, E. C.; Amaral, C.; Benedetto, L. E.; Bodie, C. L.; D'Antonio, B. I.; Davila Portillo, D. R.; Lee, R. H.; Levine, M. T.; O'Sullivan, E. C.; Pisch, N. P.; Taveras, S.; Wild, H. R.; Ross, A. P.; Albers, H. E.; Been, L. E.
10.1101/2020.06.16.154492 — neuroscience — Posted on 2020-06-17
2308 Constitutive overexpression of RAM1 increases arbuscule density during arbuscular mycorrhizal symbiosis in Brachypodium distachyon
Müller, L. M.; Campos-Soriano, L.; Levesque-Tremblay, V.; Bravo, A.; Daniels, D. A.; Pathak, S.; Park, H.-J.; Harrison, M. J.
10.1101/2020.06.15.146233 — plant biology — Posted on 2020-06-17
2311 EEG and fMRI connectomes are reliably related: a simultaneous EEG-fMRI study from 1.5T to 7T
Wirsich, J.; Jorge, J.; Iannotti, G. R.; Shamshiri, E. A.; Grouiller, F.; Abreu, R.; Lazeyras, F.; Giraud, A.-L.; Gruetter, R.; Sadaghiani, S.; Vulliemoz, S.
10.1101/2020.06.16.154625 — neuroscience — Posted on 2020-06-17
2313 Maternal hair cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner
Stoye, D. Q.; Blesa, M.; Sullivan, G.; Galdi, P.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Reynolds, R. M.; Boardman, J. P.
10.1101/2020.06.16.154922 — neuroscience — Posted on 2020-06-17
2314 Personalized vagino-cervical microbiome dynamics after oral probiotics
Chen, C.; Hao, L.; Tian, L.; Song, L.; Zhang, X.; Jie, Z.; Tong, X.; Xiao, L.; tao, z.; Jin, X.; Xu, X.; Yang, H.; Wang, J.; Kristiansen, K.; Jia, H.
10.1101/2020.06.16.155929 — microbiology — Posted on 2020-06-17
2315 Cancer-specific associations of driver genes with immunotherapy outcome
Jun, T.; Qing, T.; Dong, G.; Signaevski, M.; Hopkins, J.; Frampton, G.; Albacker, L.; Cordon-Cardo, C.; Samstein, R.; Pusztai, L.; Huang, K.-l.
10.1101/2020.06.16.155895 — genomics — Posted on 2020-06-17
2316 PEDIGREE ANALYSIS OF 222 ALMOND GENOTYPES REVEALS TWO WORLD MAINSTREAM BREEDING LINES BASED ON ONLY THREE DIFFERENT CULTIVARS
Perez de los Cobos, F.; Martinez-Garcia, P. J.; Romero, A.; Miarnau, X.; Eduardo, I.; Howad, W.; Dicenta, F.; Socias i Company, R.; Rubio-Cabetas, M. J.; Gradziel, T. M.; Whirthenshon, M.; Duval, H.; Holland, D.; Arus, P.; Vargas, F. J.; Batlle, I.
10.1101/2020.06.16.154021 — genetics — Posted on 2020-06-17
2317 Characterization of the evolutionary dynamics of influenza A H3N2 hemagglutinin
Wang, H. M.; Lou, J.; Cao, L.; Zhao, S.; Chan, P. K.; Chan, M. C.-W.; Chong, M. K.; Wu, W. K.; Chan, R. W.; Wei, Y.; Zhang, H.; Zee, B. C.; Yeoh, E.-k.
10.1101/2020.06.16.155994 — evolutionary biology — Posted on 2020-06-17
2319 Four different mechanisms for switching cell polarity
Tostevin, F.; Wigbers, M.; Sogaard-Andersen, L.; Gerland, U.
10.1101/2020.06.16.155952 — biophysics — Posted on 2020-06-17
2321 Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs
Shiver, A. L.; Osadnik, H.; Peters, J. M.; Mooney, R. A.; Wu, P. I.; Hu, J. C.; Landick, R.; Huang, K. C.; Gross, C. A.
10.1101/2020.06.16.155770 — systems biology — Posted on 2020-06-17
2323 Language impairment with a partial duplication of DOCK8
Benitez-Burraco, A.; Fernandez-Urquiza, M.; Jimenez-Romero, M. S.
10.1101/2020.06.16.155523 — neuroscience — Posted on 2020-06-17
2325 Dynamics of altruistic fluid transport in egg development
Imran Alsous, J.; Romeo, N.; Jackson, J.; Mason, F.; Dunkel, J.; Martin, A.
10.1101/2020.06.16.155606 — developmental biology — Posted on 2020-06-17
2326 Polyclonal epitope cartography reveals the temporal dynamics and diversity of human antibody responses to H5N1 vaccination
Han, J.; Schmitz, A. J.; Richey, S. T.; Dai, Y.; Turner, H. L.; Mohammed, B. M.; Fremont, D. H.; Ellebedy, A. H.; Ward, A.
10.1101/2020.06.16.155754 — immunology — Posted on 2020-06-17
2327 A yeast BiFC-seq method for genome-wide interactome mapping
Shang, L.; Zhang, Y.; Liu, Y.; Jin, C.; Yuan, Y.; Tian, C.; Ni, M.; Bo, X.; Zhang, L.; Li, D.; He, F.; Wang, J.
10.1101/2020.06.16.154146 — genomics — Posted on 2020-06-17
2328 Asbestos accelerates disease onset in a genetic model of Malignant Pleural Mesothelioma
Farahmand, P.; Gyuraszova, K.; Rooney, C.; Raffo-Iraolagoitia, X. L.; Johnson, E.; Chernova, T.; Monteverde, T.; Blyth, K.; Duffin, R.; Carlin, L. M.; Lewis, D.; Le Quesne, J.; MacFarlane, M.; Murphy, D. J.
10.1101/2020.06.16.154815 — cancer biology — Posted on 2020-06-17
2329 Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy
Chambers, L.; Esakov, E. L.; Braley, C.; Trestan, L.; Alali, Z.; Bayik, D.; Lathia, J.; Sangwan, N.; Bazeley, P.; Joehlin-Price, A. S.; Dwidar, M.; Hajjar, A.; Ahern, P. P.; Claesen, J.; Rose, P.; Vargas, R.; Michener, C.; Reizes, O.
10.1101/2020.06.16.155226 — cancer biology — Posted on 2020-06-17
2331 3D bioprinting of co-cultured osteogenic spheroids for bone tissue fabrication
Heo, D.; Ayan, B.; Dey, M.; Banerjee, D.; Lewis, G.; Wee, H.; Ozbolat, I. T.
10.1101/2020.06.16.155143 — bioengineering — Posted on 2020-06-17
2332 Structural basis for tuning activity and membrane specificity of bacterial cytolysins
Shah, N. R.; Voisin, T. B.; Parsons, E. S.; Boyd, C. M.; Hoogenboom, B.; Bubeck, D.
10.1101/2020.06.16.154724 — biochemistry — Posted on 2020-06-17
2333 Metagenome-assembled genomes of phytoplankton communities across the Arctic Circle
Duncan, A.; Barry, K.; Daum, C.; Eloe-Fadrosh, E.; Roux, S.; Tringe, S.; Schmidt, K.; Valentin, K. U.; Varghese, N.; Grigoriev, I. V.; Leggett, R. M.; Moulton, V.; Mock, T.
10.1101/2020.06.16.154583 — microbiology — Posted on 2020-06-17
2336 AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens
Li, C.; Sutherland, D.; Hammond, S. A.; Yang, C.; Taho, F.; Bergman, L.; Houston, S.; Warren, R. L.; Wong, T.; Hoang, L. M. N.; Cameron, C. E.; Helbing, C. C.; Birol, I.
10.1101/2020.06.16.155705 — bioinformatics — Posted on 2020-06-17
2339 Mast cells participate in the development of diastolic dysfunction in diabetic obese mice
Guimbal, S.; Cornuault, L.; Hollier, P.-L.; Chapouly, C.; Bats, M.-L.; Gadeau, A.-P.; Couffinhal, T.; Renault, M.-A.
10.1101/2020.06.16.154872 — physiology — Posted on 2020-06-17
2340 Methotrexate carried in lipid core nanoparticles reduces microglial activation and is neuroprotective after ischemic cortical stroke
Pereira, E. L. R.; Dias, M. N.; dos Santos, I. R.; Ramos, A. C.; Hamoy, M.; Feio, D. C. A.; Tavoni, T. M.; da Silva, P. C. M.; Gomes-Leal, W.
10.1101/2020.06.16.155804 — neuroscience — Posted on 2020-06-17
2342 Ermin deficiency as an inside-out model of inflammatory dysmyelination
Ziaei, A.; Garcia-Miralles, M.; Radulescu, C.; Sidik, H.; Silvin, A.; Bae, H.-G.; Bonnard, C.; Yusof, N. A. B. M.; Ferrari Bardile, C.; Tan, L. J.; Ng, A. Y. J.; Tohari, S.; Dehghani, L.; Venkatesh, B.; Langley, S. R.; Shaygannejad, V.; Reversade, B.; Jung, S.; Ginhoux, F.; Pouladi, M. A.
10.1101/2020.06.16.154781 — neuroscience — Posted on 2020-06-17
2345 Towards a new treatment against polymicrobial infections: high antibacterial activity of lemon IntegroPectin against Pseudomonas aeruginosa and Escherichia coli
Presentato, A.; Scurria, A.; Albanese, L.; Picone, P.; Pagliaro, M.; Zabini, F.; Meneguzzo, F.; Alduina, R.; Nuzzo, D.; Ciriminna, R.
10.1101/2020.06.16.154229 — microbiology — Posted on 2020-06-17
2347 Peripheral Natural Killer cells from chronic hepatitis B patients display molecular hallmarks of T cell exhaustion
Marotel, M.; Villard, M.; Tout, I.; Besson, L.; Allatif, O.; Pujol, M.; Rocca, Y.; Ainouze, M.; Roblot, G.; Viel, S.; Gomez, M.; Loustaud, V.; Alain, S.; Durantel, D.; Walzer, T.; Hasan, U.; Marcais, A.
10.1101/2020.06.16.154419 — immunology — Posted on 2020-06-17
2348 Homologous chromosomes in asexual rotifer Adineta vaga suggest automixis
Simion, P.; Narayan, J.; Houtain, A.; Derzelle, A.; Baudry, L.; Nicolas, E.; Cariou, M.; Guiglielmoni, N.; Kozlowski, D.; Gaudray, F. R.; Terwagne, M.; Virgo, J.; Noel, B.; Wincker, P.; Danchin, E. G.; Marbouty, M.; Hallet, B.; Koszul, R.; Limasset, A.; Flot, J.-F.; Van Doninck, K.
10.1101/2020.06.16.155473 — evolutionary biology — Posted on 2020-06-17
2351 Helical ensembles out-perform ideal helices in Molecular Replacement
Sanchez Rodriguez, F.; Simpkin, A. J.; Davies, O. R.; Keegan, R. M.; Rigden, D. J.
10.1101/2020.06.16.154690 — bioinformatics — Posted on 2020-06-17
2352 Nitrocellulose redox permanganometry: a simple method for reductive capacity assessment
Homolak, J.; Kodvanj, I.; Babic Perhoc, A.; Virag, D.; Knezovic, A.; Osmanovic Barilar, J.; Riederer, P.; Salkovic-Petrisic, M.
10.1101/2020.06.16.154682 — biochemistry — Posted on 2020-06-17
2353 Predation drives specialized host plant associations in preadapted milkweed bugs (Heteroptera: Lygaeinae)
Petschenka, G.; Halitschke, R.; Roth, A.; Stiehler, S.; Tenbusch, L.; Züst, T.; Hartwig, C.; Moreno Gamez, J. F.; Trusch, R.; Deckert, J.; Chalusova, K.; Vilcinskas, A.; Exnerova, A.
10.1101/2020.06.16.150730 — evolutionary biology — Posted on 2020-06-17
2355 Nitric oxide coordinates histone acetylation and expression of genes involved in growth/development and stress response
Ageeva_Kieferle, A.; Georgii, E.; Winkler, B.; Ghirardo, A.; Albert, A.; Huether, P.; Mengel, A.; Becker, C.; Schnitzler, J.-P.; Durner, J.; Lindermayr, C.
10.1101/2020.06.16.154476 — plant biology — Posted on 2020-06-17
2358 ppGpp is a bacterial cell size regulator
Buke, F.; Grilli, J.; Cosentino Lagomarsino, M.; Bokinsky, G.; Tans, S.
10.1101/2020.06.16.154187 — microbiology — Posted on 2020-06-17
2361 Impact of virus subtype and host IFNL4 genotype on large-scale RNA structure formation in the genome of hepatitis C virus
Simmonds, P.; Cuypers, L.; Irving, W. L.; McLauchlan, J.; Cooke, G. S.; Barnes, E.; STOP-HCV Consortium, ; Ansari, M. A.
10.1101/2020.06.16.155150 — genomics — Posted on 2020-06-17
2362 MOCCASIN: A method for correcting for known and unknown confounders in RNA splicing analysis
Slaff, B.; Radens, C. M.; Jewell, P.; Jha, A.; Lahens, N.; Grant, G. R.; Thomas-Tikhonenko, A.; Lynch, K. W.; Barash, Y.
10.1101/2020.06.16.154674 — genomics — Posted on 2020-06-17
2365 Uncovering temporally sensitive targeting motifs for traumatic brain injury via phage display
Martinez, B. I.; Mousa, G. A.; Fleck, K.; MacCulloch, T.; Diehnelt, C. W.; Stephanopoulos, N.; Stabenfeldt, S. E.
10.1101/2020.06.16.155325 — bioengineering — Posted on 2020-06-17
2368 Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins
Steblyanko, Y.; Rajendraprasad, G.; Osswald, M.; Eibes, S.; Geley, S.; Perreira, A. J.; Maiato, H.; Barisic, M.
10.1101/2020.06.16.155259 — cell biology — Posted on 2020-06-17
2369 Targeting Scavenger Receptor Type B1 In Cholesterol-Addicted Lymphomas Abolishes Glutathione Peroxidase 4 and Results in Ferroptosis
Rink, J. S.; Lin, A.; McMahon, K. M.; Calvert, A. E.; Yang, S.; Taxter, T.; Moreira, J.; Chadburn, A.; Behdad, A.; Karmali, R.; Thaxton, C. S.; Gordon, L. I.
10.1101/2020.06.16.155242 — cancer biology — Posted on 2020-06-17
2370 Temporal dynamics of QTL effects on vegetative growth in Arabidopsis thaliana
Meyer, R. C.; Weigelt-Fischer, K.; Knoch, D.; Heuermann, M. C.; Zhao, Y.; Altmann, T.
10.1101/2020.06.11.145953 — plant biology — Posted on 2020-06-17
2372 LETR1 is a lymphatic endothelial-specific lncRNA that governs cell proliferation and migration through KLF4 and SEMA3C
Ducoli, L.; Agrawal, S.; Sibler, E.; Kouno, T.; Tacconi, C.; Hon, C.-C.; Berger, S. D.; Muellhaupt, D.; He, Y.; D'Addio, M.; Dieterich, L.; Carninci, P.; de Hoon, M. J. L.; Shin, J. W.; Detmar, M.
10.1101/2020.05.25.114546 — genomics — Posted on 2020-06-17
2373 TranSPHIRE: Automated and feedback-optimized on-the-fly processing for cryo-EM
Stabrin, M.; Schoenfeld, F.; Wagner, T.; Pospich, S.; Gatsogiannis, C.; Raunser, S.
10.1101/2020.06.16.155275 — biophysics — Posted on 2020-06-17
2375 A Single-cell RNA-seq Training and Analysis Suite using the Galaxy Framework
Tekman, M.; Batut, B.; Ostrovsky, A.; Antoniewski, C.; Clements, D.; Ramirez, F.; Etherington, G. J.; Hotz, H.-R.; Scholtalbers, J.; Manning, J. R.; Bellenger, L.; Doyle, M. A.; Heydarian, M.; Huang, N.; Soranzo, N.; Moreno, P.; Mautner, S.; Papatheodorou, I.; Nekrutenko, A.; Taylor, J.; Blankenberg, D.; Backofen, R.; Grüning, B.
10.1101/2020.06.06.137570 — bioinformatics — Posted on 2020-06-17
2376 Dissociation of task engagement and arousal effects in auditory cortex and midbrain
Saderi, D.; Schwartz, Z. P.; Heller, C. R.; Pennington, J. R.; David, S. V.
10.1101/2020.06.16.155432 — neuroscience — Posted on 2020-06-17
2378 Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity
Casares, L.; Unciti, J. D.; Prados, M. E.; Caprioglio, D.; Higgins, M.; Apendino, G.; Dinkova-Kostova, A. T.; Munoz, E.; de la Vega, L.
10.1101/2020.06.16.153981 — cell biology — Posted on 2020-06-17
2380 Hippocampus-lateral septum circuitry mediates memory for food location in rats
Davis, E. A.; Liu, C. M.; Gianatiempo, I. H.; Suarez, A. N.; Cortella, A. M.; Hahn, J. D.; Kanoski, S. E.
10.1101/2020.06.16.155721 — neuroscience — Posted on 2020-06-17
2381 Focus on the breath: Brain decoding reveals internal states of attention during meditation
Weng, H. Y.; Lewis-Peacock, J. A.; Hecht, F. M.; Uncapher, M.; Ziegler, D.; Farb, N. A.; Goldman, V.; Skinner, S.; Duncan, L. G.; Chao, M. T.; Gazzaley, A.
10.1101/461590 — neuroscience — Posted on 2020-06-17
2383 Nucleus accumbens melanin-concentrating hormone signaling promotes feeding in a sex-specific manner
Terrill, S. J.; Subramanian, K.; Lan, R.; Liu, C. M.; Cortella, A. M.; Noble, E. E.; Kanoski, S. E.
10.1101/2020.06.16.155747 — neuroscience — Posted on 2020-06-17
2384 Cdc42 GTPase Activating Proteins (GAPs) Maintain Generational Inheritance of Cell Polarity and Cell Shape in Fission Yeast
Pino, M. R.; Nunez, I.; Chen, C.; Das, M. E.; Wiley, D.; D'Urso, G.; Buchwald, P.; Vavylonis, D.; Verde, F.
10.1101/2020.06.16.151308 — cell biology — Posted on 2020-06-17
2386 Differential covariance: A new method to estimate functional connectivity in fMRI
lin, w.; Chen, Y.; Bukhari, Q.; Krishnan, G.; Bazhenov, M.; Sejnowski, T. J.
10.1101/2020.06.16.155630 — neuroscience — Posted on 2020-06-17
2389 Postsynaptic serine racemase regulates NMDA receptor function
Wong, J. M.; Folorunso, O.; Barragan, E. V.; Berciu, C.; Harvey, T. L.; DeChellis-Marks, M. R.; Glausier, J. R.; MacDonald, M. L.; Coyle, J. T.; Balu, D. T.; Gray, J. A.
10.1101/2020.06.16.155572 — neuroscience — Posted on 2020-06-16
2391 Rostrocaudal Patterning and Neural Crest Differentiation of Human Pre-Neural Spinal Cord Progenitors in vitro
Cooper, F.; Gentsch, G. E.; Mitter, R.; Bouissou, C.; Healy, L.; Hernandez-Rodriguez, A.; Smith, J. C.; Bernardo, A. S.
10.1101/2020.06.16.155564 — developmental biology — Posted on 2020-06-16
2393 Precision genetic cellular models identify therapies protective against endoplasmic reticulum stress
Lebedeva, I. V.; Wagner, M. V.; Sahdeo, S.; Lu, Y.-F.; Anyanwu-Ofili, A.; Harms, M. B.; Wadia, J. S.; Rajagopal, G.; Boland, M. J.; Goldstein, D. B.
10.1101/2020.06.03.132886 — neuroscience — Posted on 2020-06-16
2402 Demographic history shaped geographical patterns of deleterious mutation load in a broadly distributed Pacific Salmon
Rougemont, Q.; Moore, J.-S.; Leroy, T.; Normandeau, E.; Rondeau, E.; Withler, R.; Van Doornik, D.; Crane, P.; Naish, K.; Garza, J.-C.; Beacham, T. D.; Koop, B.; Bernatchez, L.
10.1101/732750 — evolutionary biology — Posted on 2020-06-16
2403 Improving the clinical performance of blood-based DNA methylation biomarkers utilizing locus-specific epigenetic heterogeneity
Miller, B. F.; Pisanic, T. R.; Margolin, G.; Petrykowska, H. M.; Athamanolap, P.; Goncearenco, A.; Osei-Tutu, A.; Annunziata, C. M.; Wang, T.-H.; Elnitski, L.
10.1101/579839 — bioinformatics — Posted on 2020-06-16
2408 Improving Landsat predictions of rangeland fractional cover with multitask learning and uncertainty
Allred, B. W.; Bestelmeyer, B. T.; Boyd, C. S.; Brown, C.; Davies, K. W.; Ellsworth, L. M.; Erickson, T. A.; Fuhlendorf, S. D.; Griffiths, T. V.; Jansen, V.; Jones, M. O.; Karl, J.; Maestas, J. D.; Maynard, J. J.; McCord, S. E.; Naugle, D. E.; Starns, H. D.; Twidwell, D.; Uden, D. R.
10.1101/2020.06.10.142489 — ecology — Posted on 2020-06-16
2411 Biophysical modeling of the SARS-CoV-2 viral cycle reveals ideal antiviral targets
Castle, B. T.; Dock, C.; Hemmat, M.; Kline, S.; Tignanelli, C.; Rajasingham, R.; Masopust, D.; Provenzano, P.; Langlois, R.; Schacker, T.; Haase, A.; Odde, D. J.
10.1101/2020.05.22.111237 — systems biology — Posted on 2020-06-16
2413 A biased adenosine A1R agonist confers analgesia without cardiorespiratory depression
Wall, M.; Hill, E.; Huckstepp, R.; Barkan, K.; Deganutti, G.; Leuenberger, M.; Preti, B.; Winfield, I.; Wei, H.; Imlach, W.; Dean, E.; Hume, C.; Hayward, S.; Oliver, J.; Zhao, F.-Y.; Spanswick, D.; Reynolds, C. A.; Lochner, M.; Ladds, G.; Frenguelli, B.
10.1101/2020.04.04.023945 — physiology — Posted on 2020-06-16
2415 Highly efficient and super-bright neurocircuit tracing using vector mixing-based virus cocktail
Sun, P.; Jin, S.; Tao, S.; Wang, J.; Li, A.; Li, N.; Wu, Y.; Kuang, J.; Liu, Y.; Wang, L.; Lin, H.; Lv, X.; Liu, X.; Peng, J.; Zhang, S.; Xu, M.; Luo, Z.; He, X.; Xu, T.; Li, X.; Zeng, S.; Zhang, Y.-H.; Xu, F.
10.1101/705772 — neuroscience — Posted on 2020-06-16
2419 CYCLODEXTRIN DERIVATIVE ENHANCES THE OPHTHALMIC DELIVERY OF POORLY SOLUBLE AZITHROMYCIN.
Thakur, A.; Jain, S.; Pant, A.; Sharma, A.; Kumar, R.; Sharma, G.; Singla, N.; Suttee, A.; Kumar, S.; Barnwal, R. P.; Katare, O. P.; Singh, G.
10.1101/2020.06.16.154351 — microbiology — Posted on 2020-06-16
2421 Experimental methodologies can affect pathogenicity of Batrachochytrium salamandrivorans infections
Kumar, R.; Malagon, D.; Carter, E. D.; Miller, D.; Bohanon, M.; Cusaac, J. P.; Peterson, A. C.; Gray, M. J.
10.1101/2020.06.16.154328 — ecology — Posted on 2020-06-16
2422 ASYMMETRIC EXPRESSION OF ARGONAUTES IN ARABIDOPSIS REPRODUCTIVE TISSUES
jullien, p. E.; Bonnet, D. M.; Pumplin, N.; Schroeder, J. A.; Voinnet, O.
10.1101/2020.05.18.102863 — developmental biology — Posted on 2020-06-16
2424 Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy
Grier, A.; Laniewski, N.; Gill, A. L.; Kessler, H. A.; Huyck, H.; Holden-Wiltse, J.; Bandyopadhyay, S.; Carnahan, J.; Dylag, A. M.; Topham, D. J.; Falsey, A. R.; Caserta, M. T.; Pryhuber, G. S.; Gill, S. R.; McDavid, A.; Scheible, K. M.
10.1101/736090 — immunology — Posted on 2020-06-16
2426 A neuroendocrine pathway modulating osmotic stress in Drosophila
Zandawala, M.; Nguyen, T.; Segura, M. B.; Johard, H.; Amcoff, M.; Wegener, C.; Paluzzi, J.-P.; Nassel, D. R.
10.1101/522441 — neuroscience — Posted on 2020-06-16
2427 Predicting Alzheimer's disease progression using deep recurrent neural networks
Nguyen, M.; He, T.; An, L.; Alexander, D. C.; Feng, J.; Yeo, B. T. T.
10.1101/755058 — neuroscience — Posted on 2020-06-16
2428 Machine Learning Models Identify Inhibitors of SARS-CoV-2
Gawriljuk, V. O.; Kyaw Zin, P. P.; Foil, D. H.; Bernatchez, J.; Beck, S.; Beutler, N.; Ricketts, J.; Yang, L.; Rogers, T.; Puhl, A. C.; Zorn, K. M.; Lane, T. R.; Godoy, A. S.; Olivia, G.; Siqueira-Neto, J. L.; Madrid, P.; Ekins, S.
10.1101/2020.06.16.154765 — pharmacology and toxicology — Posted on 2020-06-16
2431 Diagnostic Evidence GAuge of Single cells (DEGAS): A transfer learning framework to infer impressions of cellular and patient phenotypes between patients and single cells
Johnson, T. S.; Yu, C. Y.; Huang, Z.; Xu, S.; Wang, T.; Dong, C.; Shao, W.; Abu Zaid, M.; Wang, Y.; Bartlett, C.; Zhang, Y.; Liu, Y.; Zhang, J.; Huang, K.
10.1101/2020.06.16.142984 — bioinformatics — Posted on 2020-06-16
2434 System Identification with Biophysical Constraints: A Circuit Model of the Inner Retina
Schröder, C.; Klindt, D.; Strauss, S.; Franke, K.; Bethge, M.; Euler, T.; Berens, P.
10.1101/2020.06.16.154203 — neuroscience — Posted on 2020-06-16
2437 AGE IS ASSOCIATED WITH INCREASED EXPRESSION OF PATTERN RECOGNITION RECEPTOR GENES AND ACE2, THE RECEPTOR FOR SARS-COV-2: IMPLICATIONS FOR THE EPIDEMIOLOGY OF COVID-19 DISEASE
Bickler, S. W.; Cauvi, D. M.; Fisch, K. M.; Prieto, J. M.; Gaidry, A. D.; Thangarajah, H.; Lazar, D.; Ignacio, R.; Gerstmann, D. R.; Ryan, A. F.; Bickler, P. E.; De Maio, A.
10.1101/2020.06.15.134403 — molecular biology — Posted on 2020-06-16
2438 The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection
Beddingfield, B.; Iwanaga, N.; Zheng, W.; Roy, C. J.; Hu, T. Y.; Kolls, J.; Bix, G.
10.1101/2020.06.15.153387 — microbiology — Posted on 2020-06-16
2439 Discovery and biosynthesis of gladiochelins: unusual lipodepsipeptide siderophores from Burkholderia gladioli
Dashti, Y.; Nakou, I.; Mullins, A.; Webster, G.; Jian, X.; Mahenthiralingam, E.; Challis, G.
10.1101/2020.06.16.153940 — microbiology — Posted on 2020-06-16
2443 Negative density-dependent parasitism in a group-living carnivore
Albery, G. F.; Newman, C.; Bright Ross, J. G.; MacDonald, D. W.; Bansal, S.; Buesching, C. D.
10.1101/2020.06.15.153726 — ecology — Posted on 2020-06-16
2444 ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability
Ozkan, N.; Koppers, M.; van Soest, I.; van Harten, A.; Liv, N.; Klumperman, J.; Hoogenraad, C. C.; Farias, G. G.
10.1101/2020.06.16.153734 — cell biology — Posted on 2020-06-16
2447 Lack of susceptibility of poultry to SARS-CoV-2 and MERS-CoV
Suarez, D. L.; Pantin-Jackwood, M. J.; Swayne, D. E.; Lee, S. A.; Deblois, S. M.; Spackman, E.
10.1101/2020.06.16.154658 — microbiology — Posted on 2020-06-16
2448 TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.
Sacconi, A.; Donzelli, S.; Pulito, C.; Ferrero, S.; Morrone, A.; Rigoni, M.; Pimipinelli, F.; Ensoli, F.; Sanguineti, G.; Pellini, R.; Agrawal, N.; Izumchenko, E.; Ciliberto, G.; Gianni, A.; Muti, P.; Strano, S.; Blandino, G.
10.1101/2020.06.16.154211 — cancer biology — Posted on 2020-06-16
2449 Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters
Bryche, B.; Saint-Albin Deliot, A.; Murri, S.; Lacote, S.; Pulido, C.; Ar Gouilh, M.; Lesellier, S.; Servat, A.; Wasniewski, M.; Picard-Meyer, E.; Montchartre-Leroy, E.; Volmer, R.; Rampin, O.; Le Goffic, R.; Marianneau, P.; Meunier, N.
10.1101/2020.06.16.151704 — neuroscience — Posted on 2020-06-16
2450 Array-based analysis of SARS-CoV-2, other coronaviruses, and influenza antibodies in convalescent COVID-19 patients
Steiner, D. J.; Cognetti, J. S.; Luta, E. P.; Klose, A. M.; Bucukovski, J.; Bryan, M. R.; Schmucke, J. J.; Nguyen-Contant, P.; Sangster, M. Y.; Topham, D. J.; Miller, B. L.
10.1101/2020.06.15.153064 — immunology — Posted on 2020-06-16
2455 Neurocognitive consequences of hand augmentation
Kieliba, P.; Clode, D.; Maimon-Mor, R. O.; Makin, T. R.
10.1101/2020.06.16.151944 — neuroscience — Posted on 2020-06-16
2458 Oral drug repositioning candidates and synergistic remdesivir combinations for the prophylaxis and treatment of COVID-19
Bakowski, M. A.; Beutler, N.; Chen, E.; Nguyen, T.-T. H.; Kirkpatrick, M. G.; Parren, M.; Yang, L.; Ricketts, J.; Gupta, A. K.; Hull, M. V.; Schultz, P. G.; Burton, D. R.; Chatterjee, A. K.; McNamara, C. W.; Rogers, T. F.
10.1101/2020.06.16.153403 — microbiology — Posted on 2020-06-16
2463 Breast Cancer Cells and Macrophages in a Paracrine-Juxtacrine Loop
Onal, S.; Turker-Burhan, M.; Bati-Ayaz, G.; Yanik, H.; Pesen-Okvur, D.
10.1101/2020.06.16.154294 — cancer biology — Posted on 2020-06-16
2468 High-frequency oscillations in the internal globus pallidus: a pathophysiological biomarker in Parkinson's disease?
Johnson, L. A.; Aman, J. E.; Yu, Y.; Escobar Sanabria, D.; Wang, J.; Hill, M.; Dharnipragada, R.; Patriat, R.; Fiecas, M.; Li, L.; Schrock, L. E.; Cooper, S. E.; Johnson, M. D.; Park, M. C.; Harel, N.; Vitek, J. L.
10.1101/2020.06.16.144477 — neuroscience — Posted on 2020-06-16
2469 The in vitro antiviral activity of the anti-hepatitis C virus (HCV) drugs daclatasvir and sofosbuvir against SARS-CoV-2
Sacramento, C. Q.; Fintelman-Rodrigues, N.; Temerozo, J. R.; da Silva Gomes Dias, S.; Ferreira, A. C.; Mattos, M.; Pao, C. R. R.; de Freitas, C. S.; Cardoso Soares, V.; Bozza, F. A.; Bou-Habib, D. C.; Bozza, P. T.; Souza, T. M. L.
10.1101/2020.06.15.153411 — microbiology — Posted on 2020-06-16
2470 Comparative analysis of coronavirus genomic RNA structure reveals conservation in SARS-like coronaviruses
Sanders, W.; Fritch, E. J.; Madden, E. A.; Graham, R. L.; Vincent, H. A.; Heise, M. T.; Baric, R. S.; Moorman, N. J.
10.1101/2020.06.15.153197 — microbiology — Posted on 2020-06-16
2471 Comparing library preparation methods for SARS-CoV-2 multiplex amplicon sequencing on the Illumina MiSeq platform
Batty, E. M.; Kochakarn, T.; Wangwiwatsin, A.; Joonlasak, K.; Huang, A. T.; Panthan, B.; Jiaranai, P.; Kümpornsin, K.; Kotanan, N.; Manasatienkij, W.; Watthanachockchai, T.; Rakmanee, K.; Jones, A. R.; Fernandez, S.; Sensorn, I.; Sungkanuparph, S.; Pasomsub, E.; Klungthong, C.; Chookajorn, T.; Chantratita, W.
10.1101/2020.06.16.154286 — genomics — Posted on 2020-06-16
2473 The IMEx Coronavirus interactome: an evolving map of Coronaviridae-Host molecular interactions
Perfetto, L.; Pastrello, C.; Del-Toro, N.; Duesbury, M.; Iannuccelli, M.; Kotlyar, M.; Licata, L.; Meldal, B.; Panneerselvam, K.; Panni, S.; Rahimzadeh, N.; Ricard-Blum, S.; Salwinski, L.; Shrivastava, A.; Cesareni, G.; Pellegrini, M.; Orchard, S.; Jurisica, I.; Hermjakob, H.; Porras, P.
10.1101/2020.06.16.153817 — bioinformatics — Posted on 2020-06-16
2478 Cell entry of SARS-CoV-2 conferred by angiotensin-converting enzyme 2 (ACE2) of different species
Tang, Y.-D.; Li, Y.; Sun, J.; Zhang, H.; Wang, T.-y.; Sun, M.-X.; Yang, Y.-L.; Hu, X.; Zhao, J.; Cai, X.
10.1101/2020.06.15.153916 — microbiology — Posted on 2020-06-16
2479 Catch and kill airborne SARS-CoV-2 to control spread of COVID-19 by a heated air disinfection system
Yu, L.; Peel, G. K.; Cheema, F. H.; Lawrence, W. S.; Bukreyeva, N.; Jinks, C. W.; Peel, J. E.; Peterson, J. W.; Paessler, S.; Hourani, M.; Ren, Z.
10.1101/2020.06.13.150243 — microbiology — Posted on 2020-06-16
2480 SVEP1, a novel human coronary artery disease locus, promotes atherosclerosis
Jung, I.-H.; Elenbaas, J. S.; Alisio, A.; Santana, K.; Young, E. P.; Kang, C. J.; Kachroo, P.; Lavine, K. J.; Razani, B.; Mecham, R. P.; Stitziel, N. O.
10.1101/2020.06.15.151027 — genetics — Posted on 2020-06-16
2481 Density Dependent Resource Budget Model for Alternate Bearing
Esmaeili, S.; Hastings, A.; Abbott, K.; Machta, J.; Reddy Nareddy, V.
10.1101/2020.06.15.148924 — ecology — Posted on 2020-06-16
2482 COVID-19-related coagulopathy, is transferrin a missing link?
McLaughlin, K.-M.; Bechtel, M.; Bojkova, D.; Ciesek, S.; Wass, M. N.; Michaelis, M.; Cinatl, J. N.
10.1101/2020.06.11.147025 — microbiology — Posted on 2020-06-16
2484 Metagenomic characterization of soil microbial communities in the Luquillo experimental forest (Puerto Rico) and implications for nitrogen cycling
Karthikeyan, S.; Orellana, L. H.; Johnston, E. R.; Hatt, J.; Löffler, F. E.; Ayala-del-Rio, H.; Gonzalez, G.; Konstantinidis, K. T.
10.1101/2020.06.15.153866 — microbiology — Posted on 2020-06-16
2485 An integrated gene catalog of the zebrafish gut microbiome reveals significant homology with mammalian microbiomes
Gaulke, C. A.; Beaver, L.; Armour, C.; Humphreys, I. R.; Barton, C.; Tanguay, R. L.; Ho, E.; Sharpton, T. J.
10.1101/2020.06.15.153924 — microbiology — Posted on 2020-06-16
2487 Wnt-and Glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division
Habib, S.; Junyent, S.; Reeves, J. C.; Szczerkowski, J. L. A.; Garcin, C. L.; Trieu, T.-J.; Wilson, M.
10.1101/2020.06.16.154609 — cell biology — Posted on 2020-06-16
2490 PQS-Induced Outer Membrane Vesicles Enhance Biofilm Dispersion in Pseudomonas aeruginosa
Cooke, A. C.; Florez, C.; Dunshee, E. B.; Lieber, A. D.; Terry, M. L.; Light, C. J.; Schertzer, J. W.
10.1101/2020.06.15.153908 — microbiology — Posted on 2020-06-16
2492 In vivo fluorescence lifetime imaging captures metabolic changes in macrophages during wound responses in zebrafish
Miskolci, V.; Tweed, K.; Lasarev, M.; Britt, E. C.; McDougal, C. E.; Walsh, A. J.; Fan, J.; Sauer, J.-D.; Skala, M.; Huttenlocher, A.
10.1101/2020.06.16.153361 — immunology — Posted on 2020-06-16
2495 Experimental investigation of Caenorhabditis elegans motility using micro-PIV
Ravikumar, S.; Fedrizzi, M.; Ranganathan, P.; Pocock, R.; O Bryan, M. K.; Soria, J.
10.1101/2020.06.16.119396 — neuroscience — Posted on 2020-06-16
2496 The ribbon-helix-helix domain proteins CdrS and CdrL regulate cell division in archaea
Darnell, C. L.; Zheng, J.; Wilson, S.; Bertoli, R. M.; Bisson-Filho, A. W.; Garner, E. C.; Schmid, A.
10.1101/2020.06.16.153114 — microbiology — Posted on 2020-06-16
2497 Red fox viromes across an urban-rural gradient
Campbell, S. J.; Ashley, W.; Gil-Fernandez, M.; Newsome, T. M.; Di Giallonardo, F.; Ortiz-Baez, A. S.; Mahar, J. E.; Towerton, A. L.; Gillings, M.; Holmes, E. C.; Carthey, A. J.; Geoghegan, J. L.
10.1101/2020.06.15.153858 — microbiology — Posted on 2020-06-16
2498 Interspecies comparative metagenomics reveals correlated gut microbiome functional capacities among vertebrates
Gaulke, C. A.; Armour, C. R.; Humphreys, I. R.; Beaver, L. M.; Carbone, L.; Ho, E.; Tanguay, R. L.; Jiang, Y.; Sharpton, T. J.
10.1101/2020.06.15.153320 — microbiology — Posted on 2020-06-16
2500 Airway-associated macrophages in homeostasis and repair
Engler, A. E.; Ysasi, A. B.; Pihl, R. M.; Villacorta-Martin, C.; Heston, H. M.; Richardson, H. M.; Moniz, N. R.; Belkina, A. C.; Mazzilli, S. A.; Rock, J. R.
10.1101/2020.06.16.146035 — cell biology — Posted on 2020-06-16
2502 An Organoid for woven Bone
Akiva, A.; Melke, J.; Ansari, S.; Liv, N.; van der Meijden, R.; van Erp, M.; Zhao, F.; Stout, M.; Nijhuis, W. H.; de Heus, C.; Muniz Ortera, C.; Fermie, J.; Klumperman, J.; Ito, K.; Sommerdijk, N.; Hofmann, S.
10.1101/2020.06.15.152959 — bioengineering — Posted on 2020-06-16
2506 piRNAs prevent runaway amplification of siRNAs from ribosomal RNAs and histone mRNAs
Montgomery, B. E.; Vijayasarathy, T.; Marks, T. N.; Reed, K. J.; Montgomery, T. A.
10.1101/2020.06.15.153023 — genetics — Posted on 2020-06-16
2510 Miniaturized Devices for Bioluminescence Imaging in Freely Behaving Animals
Celinskis, D.; Friedman, N.; Koksharov, M.; Murphy, J.; Gomez-Ramirez, M.; Borton, D.; Shaner, N.; Hochgeschwender, U.; Lipscombe, D.; Moore, C.
10.1101/2020.06.15.152546 — bioengineering — Posted on 2020-06-16
2511 Production and analysis of a mammalian septin hetero-octamer complex
DeRose, B. T.; Kelley, R. S.; Ravi, R.; Kokona, B.; Spiliotis, E. T.; Padrick, S. B.
10.1101/2020.06.15.152751 — biochemistry — Posted on 2020-06-16
2514 Age-related dedifferentiation and hyperdifferentiation of perceptual and mnemonic representations
Deng, L.; Davis, S. W.; Monge, Z. A.; Wing, E. A.; Geib, B. R.; Raghunandan, A.; Cabeza, R.
10.1101/2020.06.15.151217 — neuroscience — Posted on 2020-06-16
2516 Recombinant T cell receptors specific for HLA-A*02:01-restricted neoepitopes containing KRAS codon 12 hotspot mutations
Rive, C. M.; Yung, E.; Hughes, C. S.; Brown, S. D.; Sharma, G.; Dreolini, L.; Mawji, N. M.; Warren, C.; Karasinska, J.; Loree, J. M.; Yapp, D. T.; Morin, G. B.; Renouf, D. J.; Schaeffer, D. F.; Turcotte, S.; Holt, R. A.
10.1101/2020.06.15.149021 — immunology — Posted on 2020-06-16
2517 Dissecting Autism Genetic Risk Using Single-cell RNA-seq Data
Chen, S.; Zhou, X.; Byington, E.; Bruce, S. L.; Zhang, H.; Shen, Y.
10.1101/2020.06.15.153031 — genomics — Posted on 2020-06-16
2519 Protein tyrosine phosphatase-PEST (PTP-PEST) mediates hypoxia-induced endothelial autophagy and angiogenesis through AMPK activation
Chandel, S.; Manikandan, A.; Mehta, N.; Nathan, A. A.; Tiwari, R. K.; Mohapatra, S. B.; Chandran, M.; Jaleel, A.; Manoj, N.; Dixit, M.
10.1101/2020.06.15.152942 — cell biology — Posted on 2020-06-16
2521 stLFRsv: a germline SV analysis pipeline using co-barcoded reads
Guo, J.; Shi, C.; Chen, X.; Wang, O.; Liu, P.; Yang, H.; Xu, X.; Zhang, W.; Zhu, H.
10.1101/2020.06.15.141721 — bioinformatics — Posted on 2020-06-16
2524 Demonstration of re-epithelialization in a bioprinted human skin equivalent wound model
Poblete Jara, C.; Catarino, C. M.; Lei, Y.; Velloso, L. A.; Karande, P.; Velander, W. H.; P Araujo, E.
10.1101/2020.06.15.152140 — bioengineering — Posted on 2020-06-16
2525 A multiple ion-uptake phenotyping platform reveals shared mechanisms that affect nutrient uptake by maize roots
Griffiths, M. D.; Roy, S.; Guo, H.; Seethepalli, A.; Huhman, D.; Ge, Y.; Sharp, R. E.; Fritschi, F. B.; York, L. M.
10.1101/2020.06.15.153601 — plant biology — Posted on 2020-06-16
2527 Chemical Systems Biology Reveals Mechanisms of Dissociated Glucocorticoid Receptor Signaling
Bruno, N.; Nwachukwu, J. C.; Srinivasan, S.; Nettles, C. C.; Izard, T.; Jin, z.; Boregowda, S.; Phinney, D.; Elemento, O.; Liu, X.; Ortlund, E. A.; Houtman, R.; Stavreva, D.; Hager, G.; Kamencka, T.; Kojetin, D.; Nettles, K. W.
10.1101/2020.06.15.153270 — pharmacology and toxicology — Posted on 2020-06-16
2529 Citrulline supplementation improves spatial memory in a murine model for Alzheimer's disease
Martinez-Gonzalez, K.; Serrano-Cuevas, L.; Almeida-Gutierrez, E.; Flores-Chavez, S.; Mejia-Arangure, J. M.; Garcia-delaTorre, P.
10.1101/2020.06.15.153346 — neuroscience — Posted on 2020-06-16
2533 Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms
Serricchio, M.; Hierro-Yap, C.; Schädeli, D.; Ben Hamidane, H.; Hemphill, A.; Graumann, J.; Zikova, A.; Bütikofer, P.
10.1101/2020.06.15.152785 — biochemistry — Posted on 2020-06-16
2538 Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy
Mills, S. A.; Jobling, A.; Dixon, M. A.; Bui, B. V.; Vessey, K. A.; Phipps, J. A.; Greferath, U.; Venables, G.; Wong, V. H. Y.; Wong, C. H. Y.; He, Z.; Hui, F.; Young, J. C.; Tonc, J.; Ivanova, E.; Sagdullaev, B. T.; Fletcher, E. L.
10.1101/2020.06.15.151464 — cell biology — Posted on 2020-06-16
2539 CyTOF analysis identifies unusual immune cells in urine of BCG-treated bladder cancer patients
Castellano, E.; Samba, C.; Esteso, G.; Simpson, L. J.; Vendrame, E.; Garcia-Cuesta, E. M.; Lopez-Cobo, S.; Alvarez-Maestro, M.; Linares, A.; Leibar, A.; Ranganath, T.; Reyburn, H. T.; Martinez-Pineiro, L.; Blish, C.; Vales-Gomez, M.
10.1101/2020.06.12.147710 — immunology — Posted on 2020-06-16
2542 Selective REM-Sleep Suppression Increases Next-Day Negative Affect and Amygdala Responses to Social Exclusion
Glosemeyer, R. W.; Diekelmann, S.; Cassel, W.; Koehler, U.; Kesper, K.; Westermann, S.; Steffen, A.; Borgwardt, S.; Wilhelm, I.; Mueller-Pinzler, L.; Paulus, F. M.; Krach, S.; Stolz, D. S.
10.1101/2020.06.15.148759 — neuroscience — Posted on 2020-06-16
2543 Cell competition, the kinetics of thymopoiesis and thymus cellularity are regulated by double negative 2 to 3 early thymocytes
Ramos, C. V.; Ballesteros-Arias, L.; Silva, J. G.; Paiva, R. A.; Nogueira, M.; Carneiro, J.; Gjini, E.; Martins, V. C.
10.1101/2019.12.21.885673 — immunology — Posted on 2020-06-16
2550 Improving oligo-conjugated antibody signal in multimodal single-cell analysis
Buus, T. B.; Herrera, A.; Ivanova, E.; Mimitou, E.; Cheng, A.; Papagiannakopoulos, T.; Smibert, P.; Odum, N.; Koralov, S. B.
10.1101/2020.06.15.153080 — genomics — Posted on 2020-06-16
2554 Do carbonated beverages reduce bleeding from gill injuries in angled Northern Pike?
Trahan, A.; Chhor, A.; Lawrence, M. J.; Brownscombe, J. W.; Glassman, D.; Reid, C.; Abrams, A.; Danylchuk, A. J.; Cooke, S. J.
10.1101/2020.06.15.150797 — ecology — Posted on 2020-06-16
2556 Tissue ingrowth markedly reduces mechanical anisotropy and stiffness in fibre direction of highly aligned electrospun polyurethane scaffolds
Krynauw, H.; Buescher, J.; Koehne, J.; Verrijt, L.; Limbert, G.; Davies, N. H.; Bezuidenhout, D.; Franz, T.
10.1101/779942 — bioengineering — Posted on 2020-06-15
2559 Synthetic Turing patterns in engineered microbial consortia
Nebreda, S. D.; Pla, J.; Vidiella Rocamora, B.; Pinero, J.; Conde, N.; Sole, R.
10.1101/2020.06.15.153205 — synthetic biology — Posted on 2020-06-15
2561 Linking cerebellar functional gradients to transdiagnostic behavioral dimensions of psychopathology
Dong, D.; Guell, X.; Genon, S.; Wang, Y.; Chen, J.; Eickhoff, S. B.; Luo, C.; Yao, D.
10.1101/2020.06.15.153254 — neuroscience — Posted on 2020-06-15
2562 Identification of new insect Host Defense Peptides (HDP) from Dung Beetles (Coleoptera: Scarabaeidae) transcriptomes
Tellez, G. A.; Toro Segovia, L. J.; Osorio-Mendez, J. F.; Henao, D. C.; Franco, J.; Rojas-Montoya, M.; Castano, J. C.
10.1101/2020.06.15.152363 — molecular biology — Posted on 2020-06-15
2565 Dissecting transcriptomic signatures of genotype x genotype interactions during the initiation of plant-rhizobium symbiosis
Fagorzi, C.; Bacci, G.; Huang, R.; Cangioli, L.; Checcucci, A.; Fini, M.; Perrin, E.; Natali, C.; diCenzo, G. C.; Mengoni, A.
10.1101/2020.06.15.152710 — microbiology — Posted on 2020-06-15
2568 PROTECTIVE ANTIBODIES AGAINST HPIV3 INFECTION
Boonyaratanakornkit, J.; Weidle, C.; Singh, S.; Bakthavatsalam, R.; Perkins, J.; Stewart-Jones, G. B. E.; Kwong, P. D.; McGuire, A. T.; Pancera, M.; Taylor, J. J.
10.1101/2020.06.15.153478 — immunology — Posted on 2020-06-15
2572 Surprising amount of stasis in repetitive genome content across the Brassicales
Beric, A.; Mabry, M. E.; Harkess, A. E.; Schranz, M. E.; Conant, G. C.; Edger, P. P.; Meyers, B. C.; Pires, J. C.
10.1101/2020.06.15.153296 — evolutionary biology — Posted on 2020-06-15
2579 Discovery of a novel simian pegivirus in common marmosets (Callithrix jacchus) with lymphocytic enterocolitis
Heffron, A. S.; Lauck, M.; Somsen, E. D.; Townsend, E. C.; Bailey, A. L.; Sosa, M.; Eickhoff, J. C.; Capuano, S.; Newman, C. M.; Kuhn, J.; Mejia, A.; Simmons, H. A.; OConnor, D.
10.1101/2020.05.24.113662 — microbiology — Posted on 2020-06-15
2581 Drug2ways: Reasoning over causal paths in biological networks for drug discovery
Rivas-Barragan, D.; Mubeen, S.; Guim-Bernat, F.; Hofmann-Apitius, M.; Domingo-Fernandez, D.
10.1101/2020.06.07.138388 — bioinformatics — Posted on 2020-06-15
2583 Sweet taste of heavy water
Ben Abu, N.; Mason, P. E.; Klein, H.; Dubovski, N.; Ben Shoshan-Galeczki, Y.; Malach, E.; Prazienkova, V.; Maletinska, L.; Tempra, C.; Chamorro, V. C.; Cvacka, J.; Behrens, M.; Niv, M. Y.; Jungwirth, P.
10.1101/2020.05.22.110205 — biochemistry — Posted on 2020-06-15
2584 Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Wang, Y.; Brodin, E.; Nishii, K.; Frieboes, H. B.; Mumenthaler, S.; Sparks, J. L.; Macklin, P.
10.1101/2020.05.04.074989 — systems biology — Posted on 2020-06-15
2587 Changes in the functional connectome and behavior after exposure to chronic stress and increasing neurogenesis
Culig, L.; Steadman, P. E.; Kenney, J. W.; Legendre, S.; Minier, F.; Hen, R.; Frankland, P. W.; Belzung, C.
10.1101/2020.06.15.152553 — neuroscience — Posted on 2020-06-15
2588 A learned map for places and concepts in the human MTL
Herweg, N. A.; Kunz, L.; Brandt, A.; Wanda, P. A.; Sharan, A. D.; Sperling, M. R.; Schulze-Bonhage, A.; Kahana, M. J.
10.1101/2020.06.15.152504 — neuroscience — Posted on 2020-06-15
2589 Naturally mutated spike proteins of SARS-CoV-2 variants show differential levels of cell entry
Ozono, S.; Zhang, Y.; Ode, H.; Seng, T. T.; Imai, K.; Miyoshi, K.; Kishigami, S.; Ueno, T.; Iwatani, Y.; Suzuki, T.; Tokunaga, K.
10.1101/2020.06.15.151779 — microbiology — Posted on 2020-06-15
2590 Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera
Pape, C.; Remme, R.; Wolny, A.; Olberg, S.; Wolf, S.; Cerrone, L.; Cortese, M.; Klaus, S.; Lucic, B.; Ullrich, S.; Anders-Össwein, M.; Wolf, S.; Berati, C.; Neufeld, C.; Ganter, M.; Schnitzler, P.; Merle, U.; Lusic, M.; Boulant, S.; Stanifer, M.; Bartenschlager, R.; Hamprecht, F. A.; Kreshuk, A.; Tischer, C.; Kräusslich, H.-G.; Müller, B.; Laketa, V.
10.1101/2020.06.15.152587 — microbiology — Posted on 2020-06-15
2591 Genome-wide mapping of therapeutically-relevant SARS-CoV-2 RNA structures
Manfredonia, I.; Nithin, C.; Ponce-Salvatierra, A.; Ghosh, P.; Wirecki, T. K.; Marinus, T.; Ogando, N. S.; Snijder, E. J.; van Hemert, M. J.; Bujnicki, J. M.; Incarnato, D.
10.1101/2020.06.15.151647 — genetics — Posted on 2020-06-15
2594 The SARSCoV2 spike protein alters barrier function in 2D static and 3D microfluidic in vitro models of the human blood-brain barrier
Buzhdygan, T. P.; DeOre, B. J.; Baldwin-Leclair, A.; McGary, H.; Razmpour, R.; Galie, P. A.; Potula, R.; Andrews, A. M.; Ramirez, S. H.
10.1101/2020.06.15.150912 — neuroscience — Posted on 2020-06-15
2595 Foxa1/2 downregulates liver differentiation markers and the endoderm and liver gene regulatory network in human stem cells and in a human stable liver cell line
Warren, I. T.; Maloy, M. H.; Guiggey, D.; Ogoke, O.; Groth, T. S.; Mon, T.; Meamardoost, S.; Liu, X.; Szeglowski, A.; Thompson, R.; Chen, P.; Paulmurugan, R.; Parashurama, N.
10.1101/2020.06.01.128108 — bioengineering — Posted on 2020-06-15
2596 Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis
Herrera, N. G.; Morano, N. C.; Celikgil, A.; Georgiev, G. I.; Malonis, R. J.; Lee, J. H.; Tong, K.; Vergnolle, O.; Massimi, A. B.; Yen, L. Y.; Noble, A. J.; Kopylov, M.; Bonanno, J. B.; Garrett-Thompson, S. C.; Hayes, D. B.; Brenowitz, M.; Garforth, S. J.; Eng, E. T.; Lai, J. R.; Almo, S. C.
10.1101/2020.06.14.150607 — biochemistry — Posted on 2020-06-15
2599 JuSpace: A tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps
Dukart, J.; Holiga, S.; Rullmann, M.; Lanzenberger, R.; Hawkins, P. C. T.; Mehta, M. A.; Hesse, S.; Barthel, H.; Sabri, O.; Jech, R.; Eickhoff, S. B.
10.1101/2020.04.17.046300 — neuroscience — Posted on 2020-06-15
2601 Seroprevalence and parasite rates of Plasmodium malariae in a high malaria transmission setting of southern Nigeria.
Oriero, E. C.; Olukosi, A. Y.; Oduwole, O.; Djimde, A.; D'Alessandro, U.; Meremikwu, M.; Amambua-Ngwa, A.
10.1101/725796 — microbiology — Posted on 2020-06-15
2602 An enzyme-based immunodetection assay to quantify SARS-CoV-2 infection
Conzelmann, C.; Gilg, A.; Gross, R.; Schuetz, D.; Preising, N.; Staendker, L.; Jahrsdoerfer, B.; Schrezenmeier, H.; Sparrer, K. M.; Stamminger, T.; Stenger, S.; Muench, J.; Mueller, J. A.
10.1101/2020.06.14.150862 — microbiology — Posted on 2020-06-15
2603 A novel biparatopic antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy
Miao, X.; Luo, Y.; Huang, X.; Lee, S. M. Y.; Yuan, Z.; Tang, Y.; Chen, L.; Wang, C.; Jiang, W.; Gao, W.; Song, X.; Yan, Y.; Pang, T.; Zou, Y.; Fu, W.; Wan, L.; Jramillo, J. G.; Knight, M.; Tan, T. K.; Rijal, P.; Townsend, A.; Sun, J.; Liu, X.; James, W. S.; Tsun, A.; Xu, Y.
10.1101/2020.06.14.147868 — immunology — Posted on 2020-06-15
2605 Novel ACE2-IgG1 fusions with increased activity against SARS-CoV-2
Iwanaga, N.; Cooper, L.; Rong, L.; Beddingfield, B.; Crabtree, J.; Tripp, R. A.; Kolls, J.
10.1101/2020.06.15.152157 — immunology — Posted on 2020-06-15
2607 Effectiveness of active learning for ecology teaching: the perspective of students vs their grades
Sperber, C. F.; Szinwelski, N.; Ferreira, F. F.; Paiva, L. F.; Prasniewski, V. M.; Teixeira, A. F. d. P.; Costa, B. C.; Campos, R. B. F.; Vaz de Mello, R. M. A.; Wiggins, B.
10.1101/2020.04.02.021584 — ecology — Posted on 2020-06-15
2610 Data-driven inference of crosstalk in the tumor microenvironment
Ghoshdastider, U.; Naeini, M. M.; Rohatgi, N.; Revkov, E.; Wong, A.; Solai, S.; Nguyen, T. T.; Yeong, J.; Iqbal, J.; Tan, P. H.; Chowbay, B.; DasGupta, R.; Jacobsen Skanderup, A.
10.1101/835512 — cancer biology — Posted on 2020-06-15
2613 Direct anabolic three carbon metabolism via propionate to a six carbon metabolite occurs in human heart and in vivo across mouse tissues
Doan, M. T.; Neinast, M. D.; Varner, E. L.; Bedi, K.; Bartee, D.; Jiang, H.; Trefely, S.; Xu, P.; Singh, J. P.; Jiang, C.; Rame, E.; Brady, D.; Meier, J. L.; Marguiles, K.; Arany, Z.; Snyder, N. W.
10.1101/758706 — biochemistry — Posted on 2020-06-15
2617 Efficient sampling and noisy decisions
Heng, J. A.; Woodford, M.; Polania, R.
10.1101/799064 — neuroscience — Posted on 2020-06-15
2627 Pre-existing immunity provides a barrier to airborne transmission of influenza viruses
Lakdawala, S.; Le Sage, V.; Jones, J.; Kormuth, K.; Fitzsimmons, W.; Nturibi, E.; Padovani, G.; Arevalo, C.; French, A.; Avery, A.; Manivanh, R.; McGrady, E. E.; Bhagwat, A.; Lauring, A. S.; Hensley, S. E.
10.1101/2020.06.15.103747 — microbiology — Posted on 2020-06-15
2631 Resident macrophages establish and control lipid stores via PDGFcc production
Cox, N.; Crozet, L.; Holtman, I. R.; Loyher, P.-L.; Lazarov, T.; Mass, E.; Stanley, R.; Glass, C. K.; Geissmann, F.
10.1101/2020.06.15.152397 — immunology — Posted on 2020-06-15
2632 An Atlas of Phosphorylation and Proteolytic Processing Events During Excitotoxic Neuronal Death Reveals New Therapeutic Opportunities
Ameen, S. S.; Dufour, A.; Hossain, M. I.; Hoque, A.; Sturgeon, S.; Nandurkar, H.; Draxler, D.; Medcalf, R.; Kamaruddin, M. A.; Lucet, I.; Leeming, M.; Liu, D.; Dhillon, A.; Lim, J. P.; Zhu, H.; Bokhari, L.; Roulston, C.; Kleifeld, O.; Ciccotosto, G.; Williamson, N. A.; Ang, C.-S.; Cheng, H. C.
10.1101/2020.06.15.151456 — biochemistry — Posted on 2020-06-15
2636 Deep Learning for Cortical Potential Imaging
Razorenova, A.; Yavich, N.; Malovichko, M.; Fedorov, M.; Koshev, N.; Dylov, D. V.
10.1101/2020.06.15.151480 — neuroscience — Posted on 2020-06-15
2640 Robust coding with spiking networks: a geometric perspective
Calaim, N.; Dehmelt, F. A.; Goncalves, P. J.; Machens, C. K.
10.1101/2020.06.15.148338 — neuroscience — Posted on 2020-06-15
2641 Identification of mtROS-sensitive processes in activated CD4+ T cells
Meston, D. J.; Bi, W.; Rietschel, T.; van Ham, M.; Leichert, L. I.; Jansch, L.
10.1101/2020.06.15.152116 — immunology — Posted on 2020-06-15
2642 Genome sequence of Hydrangea macrophylla and its application in analysis of the double flower phenotype
Nashima, K.; Shirasawa, K.; Ghelfi, A.; Hirakawa, H.; Isobe, S.; Suyama, T.; Wada, T.; Kurokura, T.; Uemachi, T.; Azuma, M.; Akutsu, M.; Kodama, M.; Nakazawa, Y.; Namai, K.
10.1101/2020.06.14.151431 — genomics — Posted on 2020-06-15
2643 Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
Kang, Y.-L.; Chou, Y.-Y.; Rothlauf, P. W.; Liu, Z.; Soh, T. K.; Cureton, D.; Case, J. B.; Chen, R. E.; Diamond, M. S.; Whelan, S. P. J.; Kirchhausen, T.
10.1101/2020.04.21.053058 — cell biology — Posted on 2020-06-15
2644 GluD2- and Cbln1-mediated Competitive Synaptogenesis Shapes the Dendritic Arbors of Cerebellar Purkinje Cells
Takeo, Y. H.; Shuster, A.; Jiang, L.; Hu, M.; Luginbuhl, D.; Rulicke, T.; Contreras, X.; Hippenmeyer, S.; Wagner, M.; Ganguli, S.; Luo, L.
10.1101/2020.06.14.151258 — neuroscience — Posted on 2020-06-15
2645 Genetic Variation Regulates Opioid-Induced Respiratory Depression in Mice
Bubier, J. A.; He, H.; Philip, V. M.; Roy, T.; Monroy Hernandez, C.; Donohue, K. D.; O'Hara, B. F.; Chesler, E. A.
10.1101/2020.06.15.152249 — genetics — Posted on 2020-06-15
2646 Modulation of Aplnr signaling is required during the development and maintenance of the hematopoietic system
Jackson, M.; Fidanza, A.; Taylor, A. H.; Rybtsov, S.; Axton, R. A.; Kydonaki, M.; Meek, S.; Burdon, T.; Medvinsky, A.; Forrester, L. M.
10.1101/2020.06.15.145649 — developmental biology — Posted on 2020-06-15
2655 Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses
Walls, J. F.; Finlay, D.; McVicar, D. W.; Gardiner, C. M.; Palmieri, E. M.; Gonzalez Cotto, M.; Subleski, J. J.
10.1101/2020.06.15.152769 — cell biology — Posted on 2020-06-15
2656 Immune Selection Pressure Contributes to Pancreatic Cancer Immune Evasion
Ajina, R.; Zuo, A.; Wang, S.; Moussa, M.; Cooper, C. J.; Shen, Y.; Johnson, Q. R.; Parks, J. M.; Smith, J. C.; Catalfamo, M.; Fertig, E. J.; Jablonski, S. A.; Weiner, L. M.
10.1101/2020.06.15.151274 — cancer biology — Posted on 2020-06-15
2661 Whole genome sequencing of global Spodoptera frugiperda populations: evidence for complex, multiple introductions across the Old World
Tay, W. T.; Rane, R.; Padovan, A.; Walsh, T.; Elfekih, S.; Downes, S.; Nam, K.; d'Alencon, E.; Zhang, J.; Wu, Y.; Negre, N.; Kunz, D.; Kriticos, D. J.; Czepak, C.; Otim, M. H.; Gordon, K. H.
10.1101/2020.06.12.147660 — genomics — Posted on 2020-06-15
2662 Genomic selection strategies for clonally propagated crops
Werner, C. R.; Gaynor, R. C.; Sargent, D. J.; Lillo, A.; Gorjanc, G.; Hickey, J. M.
10.1101/2020.06.15.152017 — genetics — Posted on 2020-06-15
2663 Binding of Calcium and Magnesium to Cardiac Troponin C
Rayani, K.; Seffernick, J. T.; Li, Y. A.; Davis, J. P.; Spuches, A.; Petegem, F. V.; Solaro, R. J.; Lindert, S.; Tibbits, G. F.
10.1101/2020.06.14.150854 — cell biology — Posted on 2020-06-15
2668 Dose-dependent enhancement of motion direction discrimination with transcranial magnetic stimulation of visual cortex
Arana, O. L. G.; Palmer, H.; Dannhauer, M.; Hile, C.; Liu, S.; Hamdan, R.; Brito, A.; Cabeza, R.; Davis, S. W.; Peterchev, A. V.; Sommer, M. A.; Appelbaum, L.
10.1101/2020.06.14.151118 — neuroscience — Posted on 2020-06-15
2669 Neural representation of linguistic feature hierarchy reflects second-language proficiency
Di Liberto, G.; Nie, J.; Yeaton, J.; Khalighinejad, B.; Shamma, S.; Mesgarani, N.
10.1101/2020.06.15.142554 — neuroscience — Posted on 2020-06-15
2670 μSPIM: A Software Platform for Selective Plane Illumination Microscopy
Saska, D.; Pichler, P.; Qian, C.; Pegasiou, C.; Buckley, C. L.; Lagnado, L.
10.1101/2020.06.15.151993 — neuroscience — Posted on 2020-06-15
2675 Control of fluid flow by Adgrd1 is essential for mammalian oviductal embryo transport
Bianchi, E.; Sun, Y.; Almansa-Ordonez, A.; Woods, M.; Goulding, D.; Martinez Martin, N.; Wright, G. J.
10.1101/2020.06.15.144444 — molecular biology — Posted on 2020-06-15
2679 Lack of mucosal cholinergic innervation is associated with increased IL-23-induced T-helper-17 response in Hirschsprung disease
Keck, S.; Galati-Fournier, V.; Kym, U.; Moesch, M.; Usemann, J.; Subotic, U.; Tharakan, S.; Krebs, T.; Stathopoulos, E.; Schmittenbecher, P.; Cholewa, D.; Romero, P.; Reingruber, B.; Bruder, E.; NIG Study Group, ; Holland-Cunz, S.
10.1101/2020.06.15.151621 — immunology — Posted on 2020-06-15
2680 Definition of a Small Core Transcriptional Circuit Regulated by AML1-ETO
Stengel, K. R.; Ellis, J.; Spielman, C. L.; Bomber, M. L.; Hiebert, S. W.
10.1101/2020.06.14.151159 — genomics — Posted on 2020-06-15
2681 Human library of cardiac promoters and enhancers
Deviatiiarov, R. M.; Gams, A.; Syunyaev, R.; Tatarinova, T. V.; Gusev, O.; Efimov, I. R.
10.1101/2020.06.14.150904 — genomics — Posted on 2020-06-15
2683 DILS : Demographic Inferences with Linked Selection by using ABC
Fraisse, C.; Popovic, I.; Romiguier, J.; Loire, E.; Simon, A.; Galtier, N.; Duret, L.; Bierne, N.; Vekemans, X.; Roux, C.
10.1101/2020.06.15.151597 — evolutionary biology — Posted on 2020-06-15
2684 Oriented Soft DNA Curtains for Single Molecule Imaging
Kopustas, A.; Ivanovaite, S.; Rakickas, T.; Poceviciute, E.; Paksaite, J.; Karvelis, T.; Zaremba, M.; Manakova, E.; Tutkus, M.
10.1101/2020.06.15.151662 — biophysics — Posted on 2020-06-15
2685 De novo genome assembly and transcriptome analysis for the drought and salt resistant Solanum sitiens
Molitor, C.; Kurowski, T. J.; Fidalgo de Almeida, P. M.; Eerolla, P.; Spindlow, D. J.; Kashyap, S. P.; Singh, B.; Prasanna, H. C.; Thompson, A. J.; Mohareb, F. R.
10.1101/2020.06.14.151043 — bioinformatics — Posted on 2020-06-15
2688 Stiffening of prostate cancer cells driven by actin filaments - microtubules crosstalk confers resistance to microtubule-targeting drugs
Kubiak, A.; Chighizola, M.; Schulte, C.; Bryniarska, N.; Wesolowska, J.; Pudelek, M.; Ryszawy, D.; Basta-Kaim, A.; Laidler, P.; Podesta, A.; Lekka, M.
10.1101/2020.06.14.146696 — biophysics — Posted on 2020-06-15
2691 A plasma membrane nanoplatform ensures signal specificity during osmotic signaling in plants
Smokvarska, M.; Francis, C.; Platre, M. P.; Fiche, J.-B.; Alcon, C.; Dumont, X.; Nacry, P.; Bayle, V.; Nollmann, M.; Maurel, C.; Jaillais, Y.; Martiniere, A.
10.1101/2020.06.14.145961 — plant biology — Posted on 2020-06-15
2695 Human Prefoldin Modulates Co-transcriptional Pre-mRNA Splicing
Payan-Bravo, L.; Penate, X.; Cases, I.; Pareja-Sanchez, Y.; Fontalva, S.; Odriozola, Y.; Lara, E.; Jimeno-Gonzalez, S.; Sune, C.; Reyes, J. C.; Chavez, S.
10.1101/2020.06.14.150466 — molecular biology — Posted on 2020-06-15
2697 Exposure to artemisinin at the trophozoite stage increases sexual conversion rates in the malaria parasite Plasmodium falciparum
Portugaliza, H. P.; Miyazaki, S.; Geurten, F. J. A.; Pell, C.; Rosanas-Urgell, A.; Janse, C. J.; Cortes, A.
10.1101/2020.06.15.151746 — microbiology — Posted on 2020-06-15
2698 Mainly on the Plane: Deep Subsurface Bacterial Proteins Bind and Alter Clathrate Structure
Johnson, A. M.; Huard, D. J. E.; Kim, J.; Raut, P.; Dai, S.; Lieberman, R. L.; Glass, J. B.
10.1101/2020.06.15.152181 — microbiology — Posted on 2020-06-15
2699 Genome-wide identification of long non-coding RNAs in the gravid ectoparasite Varroa destructor
Lin, Z.; Liu, Y.; Chen, X.; Han, C.; Wang, W.; Ke, Y.; Su, X.; Chen, H.; Xu, H.; Chen, G.; Ji, T.
10.1101/2020.06.14.151340 — genomics — Posted on 2020-06-15
2702 HMGXB4 Targets Sleeping Beauty Transposition to Vertebrate Germinal Stem Cells
Devaraj, A.; Singh, M.; Narayanavari, S.; Yong, G.; Rasko, T.; Wang, J.; Wang, J.; Becker, M.; Schorn, A.; Cseresznyes, Z.; Grzela, D.; Walisko, O.; Selbach, M.; Ivics, Z.; Izsvak, Z.
10.1101/2020.06.15.145656 — developmental biology — Posted on 2020-06-15
2703 Cannabidiol Interactions with Voltage-Gated Sodium Channels
Sait, L. G.; Sula, A.; Hollingworth, D.; Rana, R.; Whalley, B. J.; Wallace, B. A.
10.1101/2020.06.15.151720 — biophysics — Posted on 2020-06-15
2705 Reconstitution of Alveolar Regeneration via novel DATPs by Inflammatory Niches
Choi, J.; Park, J.-E.; Tsagkogeorga, G.; Yanagita, M.; Koo, B.-K.; Han, N.; Lee, J.-H.
10.1101/2020.06.14.151324 — cell biology — Posted on 2020-06-15
2708 Uncovering candidate genes involved in photosynthetic capacity using unexplored genetic variation in Spring Wheat
Joynson, R.; Molero, G.; Coombes, B.; Gardiner, L.-J.; Rivera-Amado, C.; Pinera-Chavez, F. J.; Evans, J. R.; Furbank, R. T.; Reynolds, M. P.; Hall, A.
10.1101/2020.06.15.151928 — plant biology — Posted on 2020-06-15
2713 Combined CTL and NK cell cytotoxicity against cancer cells
Friedmann, K. S.; Knoerck, A.; Cappello, S.; Hoxha, C.; Schwaer, G.; Iden, S.; Bogeski, I.; Kummerow, C.; Schwarz, E. C.; Hoth, M.
10.1101/2020.06.14.150672 — immunology — Posted on 2020-06-15
2716 Hospital outbreak of carbapenem-resistant Enterobacteriales associated with an OXA-48 plasmid carried mostly by Escherichia coli ST399
Ledda, A.; Cummins, M.; Shaw, L. P.; Jauneikaite, E.; Cole, K.; Lasalle, F.; Barry, D.; Rosmarin, C.; Anaraki, S.; Wareham, D.; Stoesser, N.; Paul, J.; Manuel, R.; Cherian, B.; Didelot, X.
10.1101/2020.06.15.148189 — evolutionary biology — Posted on 2020-06-15
2717 Calcium ion chelation preserves platelet function during cold storage
Xiang, B.; Zhang, G.; Zhang, Y.; Wu, C.; Joshi, S.; Morris, A.; Ware, J.; Smyth, S. S.; Whiteheart, S. W.; Li, Z.
10.1101/2020.06.14.150920 — cell biology — Posted on 2020-06-15
2719 Molecular simulations unravel the molecular principles that mediate selective permeability of carboxysome shell protein
Faulkner, M.; Szabo, I.; Weetman, S. L.; Sicard, F.; Huber, R. G.; Bond, P. J.; Rosta, E.; Liu, L.-N.
10.1101/2020.06.14.151241 — biophysics — Posted on 2020-06-15
2721 Ab initio Spillover Compensation in CyTOF Data
Miao, Q.; Wang, F.; Dou, J.; Iqbal, R.; Basar, R.; Muftuoglu, M.; Li, L.; Rezvani, K.; Chen, K.
10.1101/2020.06.14.151225 — bioinformatics — Posted on 2020-06-15
2722 Galaxy-SynBioCAD: Synthetic Biology Design Automation tools in Galaxy workflows
du Lac, M.; Duigou, T.; Herisson, J.; Carbonell, P.; Swainston, N.; Zulkower, V.; Shah, F.; Faure, L.; Mahdy, M.; Soudier, P.; Faulon, J.-L.
10.1101/2020.06.14.145730 — bioengineering — Posted on 2020-06-15
2723 Engineering of extracellular vesicles for display of protein biotherapeutics
Gupta, D.; Wiklander, O. P. B.; Gorgens, A.; Conceicao, M.; Corso, G.; Liang, X.; Seow, Y.; Balsu, S.; Felldin, U.; Bostancioglu, B.; Lee, Y. X. F.; Hean, J.; Mager, I.; Roberts, T. C.; Gustafsson, M.; Mohammad, D. K.; Sork, H.; Backlund, A.; Smith, C. I. E.; Wood, M. J. A.; Vandenbroucke, R.; Nordin, J.; Andaloussi, S. E.
10.1101/2020.06.14.149823 — bioengineering — Posted on 2020-06-15
2724 Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity
Fellner, M.; Parakra, R.; McDonald, K. O.; Jameson, G. N. L.; Wilbanks, S. M.; Ledgerwood, E. C.
10.1101/2020.06.14.151373 — biochemistry — Posted on 2020-06-15
2726 A high fat containing chicken egg-only diet suppresses fatty liver induced by a lipid-rich methionine and choline deficient diet.
Isobe, K.-i.; Nishio, N.; Kuzuya, A.; Kato, K.; Hatanaka, A.; Suzuki, R.; Kawai, M.; Kanjya, A.; Suitou, C.; Nagasaki, M.
10.1101/2020.06.14.151316 — pathology — Posted on 2020-06-15
2728 Integrated analysis of high throughput transcriptomic data revealed specific gene expression signature of cardiomyocytes
Omrani, M. R.; Sharifi, E.; Khazaei, N.; Jahangiri Esfahani, S.; Kieran, N. W.; Hashemi, H.; Mohammadnia, A.; Yaqubi, M.
10.1101/2020.06.14.151399 — cell biology — Posted on 2020-06-15
2729 Spindle scaling is governed by cell boundary regulation of microtubule nucleation
Rieckhoff, E.; Berndt, F.; Golfier, S.; Decker, F.; Elsner, M.; Ishihara, K.; Brugues, J.
10.1101/2020.06.15.136937 — cell biology — Posted on 2020-06-15
2730 Structure of a dominant negative mutant reveals a stalled intermediate in anthrax protective antigen pore maturation
Scott, H.; Huang, W.; Ganti, S.; Zhang, K.; Mehzabeen, N.; Day, A.; Battaile, K. P.; Lovell, S.; G. Bann, J.; Taylor, D. J.
10.1101/2020.06.15.152231 — biophysics — Posted on 2020-06-15
2731 Dynamics of Tpm1.8 domains on actin filaments with single moleculeresolution
Bareja, I.; Wioland, H.; Janco, M.; Nicovich, P. R.; JEGOU, A.; Romet-Lemonne, G.; Walsh, J.; Boecking, T.
10.1101/2020.06.15.152033 — biophysics — Posted on 2020-06-15
2732 3D microarchitecture of the human tuberculous granuloma
Wells, G. A.; Glasgow, J. N.; Nargan, K.; Lumamba, K.; Madansein, R.; Maharaj, K.; Hunter, R. L.; Naidoo, T.; Ramdial, P.; Coetzer, L.; le Roux, S.; du Plessis, A.; Steyn, A. J.
10.1101/2020.06.14.149898 — microbiology — Posted on 2020-06-15
2736 A Whole Cell Metal-Organic Framework Encapsulated Vaccine Against Septicemic UPEC Infection
Luzuriaga, M. A.; Herbert, F. C.; Brohlin, O.; Shahrivarkevishahi, A.; Wijesundara, Y. H.; Veera, K.; Benjamin, C. E.; Popal, S.; Burton, M. D.; Ingersoll, M. A.; De Nisco, N. J.; Gassensmith, J. J.
10.1101/2020.06.14.148452 — immunology — Posted on 2020-06-15
2738 Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon
Finney, L. J.; Glanville, N.; Farne, H.; Aniscenko, J.; Fenwick, P.; Kemp, S.; Trujillo-Torralbo, M.-B.; Calderazzo, M.; Wedzicha, J. A.; Mallia, P.; Bartlett, N. W.; Johnston, S. L.; Singanayagam, A.
10.1101/2020.06.13.149039 — immunology — Posted on 2020-06-15
2739 Tiger team: a panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Noy-Porat, T.; Makdasi, E.; Alcalay, R.; Mechaly, A.; Levy, Y.; Bercovich-Kinori, A.; Zauberman, A.; Tamir, H.; Yahalom-Ronen, Y.; Israeli, M.; Epstein, E.; Achdout, H.; Melamed, S.; Chitlaru, T.; Weiss, S.; Peretz, E.; Rosen, O.; Paran, N.; Yitzhaki, S.; Shapira, S. C.; Israely, T.; Mazor, O.; Rosenfeld, R.
10.1101/2020.05.20.106609 — immunology — Posted on 2020-06-15
2740 Structural and functional conservation of the programmed -1 ribosomal frameshift signal of SARS-CoV-2
Kelly, J. A.; Olson, A. N.; Neupane, K.; Munshi, S.; San Emerterio, J.; Pollack, L.; Woodside, M. T.; Dinman, J. D.
10.1101/2020.03.13.991083 — genetics — Posted on 2020-06-15
2742 Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration
Temisak, S.; Thangsunan, P.; Boonil, J.; Yenchum, W.; Hongthong, K.; Yata, T.; Solis, L. R.; Morris, P.
10.1101/2020.06.14.150375 — molecular biology — Posted on 2020-06-15
2747 Orthotopic Transplantation and Engraftment of Human Induced Pluripotent Stem Cell-Derived Alveolar Progenitor Cells into Murine Lungs
Weiner, A. I.; Fernandez, R.; Zhao, G.; Palashikar, G.; Costa, M. F.; Adams, S.; Lengner, C. E.; Johnson, F. B.; Vaughan, A. E.
10.1101/2020.06.14.149831 — developmental biology — Posted on 2020-06-15
2748 DNA sequence-directed cooperation between nucleoid-associated proteins
Japaridze, A.; Yang, W.; Dekker, C.; Nasser, W.; Muskhelishvili, G.
10.1101/2020.06.14.150516 — biophysics — Posted on 2020-06-15
2750 The Human Telomeric Proteome During Telomere Replication
Lin, C.-Y. G.; Naeger, A. C.; Lunardi, T.; Vancevska, A.; Lossaint, G.; Lingner, J.
10.1101/2020.06.14.150524 — biochemistry — Posted on 2020-06-15
2751 The bacterial effector HopZ1a acetylates MKK7 to suppress plant immunity
Rufian, J. S.; Rueda-Blanco, J.; Lopez-Marquez, D.; Macho, A.; Beuzon, C. R.; Ruiz-Albert, J.
10.1101/2020.06.14.150508 — plant biology — Posted on 2020-06-15
2755 Evaluation of Field Sampling Techniques for Environmental Microbial Exposure: Assessing Efficacy and Feasibility
Dalton, K. R.; Spicer, K.; Ludwig, S.; Clemons-Erby, D.; Green, T.; Rule, A. M.; Koehler, K.; McCormack, M. C.; Davis, M. F.
10.1101/2020.06.14.150722 — microbiology — Posted on 2020-06-15
2759 Evolutionary phenome-genome analysis of cranial suture closure in mammals
Esteve-Altava, B.; Barteri, F.; Farre, X.; Muntane, G.; Pastor, J. F.; Navarro, A.
10.1101/2020.06.15.148130 — evolutionary biology — Posted on 2020-06-15
2760 Managing mixed stands can mitigate severe climate change impacts on ecosystem functioning
JOURDAN, M.; Cordonnier, T.; Dreyfus, P.; Riond, C.; de Coligny, F.; Morin, X.
10.1101/2020.06.13.149856 — ecology — Posted on 2020-06-15
2761 Outcomes of the 2019 EMDataResource model challenge: validation of cryo-EM models at near-atomic resolution
Lawson, C. L.; Kryshtafovych, A.; Adams, P. D.; Afonine, P.; Baker, M. L.; Barad, B. A.; Bond, P.; Burnley, T.; Cao, R.; Cheng, J.; Chojnowski, G.; Cowtan, K.; Dill, K. A.; DiMaio, F.; Farrell, D.; Fraser, J. S.; Herzik, M. A.; Hoh, S. W.; Hou, J.; Hung, L.-W.; Igaev, M.; Joseph, A. P.; Kihara, D.; Kumar, D.; Mittal, S.; Monastyrskyy, B.; Olek, M.; Palmer, C.; Patwardhan, A.; Perez, A.; Pfab, J.; Pintilie, G. D.; Richardson, J. S.; Rosenthal, P. B.; Sarkar, D.; Schaefer, L. U.; Schmid, M. F.; Schroeder, G. F.; Shekhar, M.; Si, D.; Singharoy, A.; Terashi, G.; Terwilliger, T. C.; Vaiana, A.; Wan
10.1101/2020.06.12.147033 — biochemistry — Posted on 2020-06-15
2763 A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation
Sonobe, Y.; Aburas, J.; Islam, P.; Gendron, T. F.; Brown, A. E. X.; Roos, R. P.; Kratsios, P.
10.1101/2020.06.13.150029 — neuroscience — Posted on 2020-06-15
2764 Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria
Cummings, T. F.; Gori, K.; Sanchez-Pulido, L.; Gavriilidis, G.; Moi, D.; Wilson, A. R.; Murchison, E. P.; Dessimoz, C.; Ponting, C.; Christophorou, M. A.
10.1101/2020.06.13.150037 — evolutionary biology — Posted on 2020-06-15
2766 Unsupervised manifold alignment for single-cell multi-omics data
Singh, R.; Demetci, P.; Bonora, G.; Ramani, V.; Lee, C.; Fang, H.; Duan, Z.; Deng, X.; Shendure, J.; Disteche, C.; Noble, W. S.
10.1101/2020.06.13.149195 — bioinformatics — Posted on 2020-06-15
2770 Discovery of a novel small protein factor involved in the coordinated degradation of phycobilisomes in cyanobacteria
Hess, W. R.; Krauspe, V.; Macek, B.; Spaet, P.; Schilling, O.; Fahrner, M.; Steglich, C.; Frankenberg-Dinkel, N.
10.1101/2020.06.14.150680 — microbiology — Posted on 2020-06-15
2774 The extent and impact of variation in ADME genes in sub-Saharan African populations
da Rocha, J.; Othman, H.; Botha, G.; Twesigomwe, D.; Ahmed, S.; Cottino, L.; Drögemolller, B.; Fadlelmola, F.; Machanick, P.; Mbiyavanga, M.; Panji, S.; Wright, G.; Adebamowo, C.; Matshaba, M.; Ramsay, M.; Simo, G.; Simuunza, M. C.; Tiemessen, C. T.; Baldwin, S. J.; Chiano, M.; Cox, C.; Gross, A. S.; Thomas, P.; Gamo, F.-J.; Hazelhurst, S.; H3Africa Consortium,
10.1101/2020.06.14.108217 — genetics — Posted on 2020-06-14
2775 Requirement of Irf6 and Esrp1/2 in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish
Carroll, S. H.; Macias Trevino, C.; Li, E. B.-H.; Kawasaki, K.; Alhazmi, N.; Hallett, S.; Cotney, J.; Carstens, R. P.; Liao, E. C.
10.1101/2020.06.14.149773 — developmental biology — Posted on 2020-06-14
2776 Chronic Effects of Indirect and Direct Cannabinoid Receptor Agonists on Addiction-Related Behaviors and Dopamine Release
Honeywell, K. M.; Freels, T. G.; McWain, M. A.; Chaffin, A. S.; Nolen, H. G.; Sable, H. J.; Lester, D. B.
10.1101/2020.06.14.150755 — neuroscience — Posted on 2020-06-14
2777 Age-related differences in auditory cortex activity during spoken word recognition
Rogers, C. S.; Jones, M. S.; McConkey, S.; Spehar, B.; Van Engen, K. J.; Sommers, M. S.; Peelle, J. E.
10.1101/2020.03.05.977306 — neuroscience — Posted on 2020-06-14
2778 The changing mouse embryo transcriptome at whole tissue and single-cell resolution
He, P.; Williams, B. A.; Trout, D.; Marinov, G. K.; Amrhein, H.; Berghella, L.; Goh, S.-T.; Plajzer-Frick, I.; Afzal, V.; Pennacchio, L. A.; Dickel, D. E.; Visel, A.; Ren, B.; Hardison, R. C.; Zhang, Y.; Wold, B. J.
10.1101/2020.06.14.150599 — developmental biology — Posted on 2020-06-14
2779 MDM2 Inhibition in Combination with Endocrine Therapy and CDK4/6 Inhibition for the Treatment of ER-Positive Breast Cancer.
Portman, N.; Milioli, H. H.; Alexandrou, S.; Coulson, R.; Yong, A.; Fernandez, K. J.; Chia, K.; Segara, D.; Parker, A.; Haupt, S.; Haupt, Y.; Tilley, W. D.; Swarbrick, A.; Caldon, C. E.; Lim, E.
10.1101/2020.06.09.140921 — cancer biology — Posted on 2020-06-14
2780 Local frustration determines loop opening during the catalytic cycle of an oxidoreductase
Stelzl, L. S.; Mavridou, D. A. I.; Saridakis, E.; Gonzalez, D.; Baldwin, A.; Ferguson, S. J.; Sansom, M.; Redfield, C.
10.1101/686949 — biophysics — Posted on 2020-06-14
2782 Extensive individual differences of category information in ventral temporal cortex in the congenitally blind
Rosenke, M.; van den Hurk, J.; Margalit, E.; Op de Beeck, H. P.; grill-spector, k.; Weiner, K. S.
10.1101/2020.06.14.151092 — neuroscience — Posted on 2020-06-14
2789 Genotypic and antigenic study of SARS-CoV-2 from an Indian isolate.
Dhar, R.; Sinha, A. Y.; Seethy, A. A.; Matta, S. A.; Pethusamy, K.; Srivastava, T.; Singh, S.; Mukherjee, I.; Sarkar, S.; Minocha, R.; Purkayastha, K.; Sharma, J. B.; Paine, S.; Karmakar, S.
10.1101/2020.06.10.140657 — biochemistry — Posted on 2020-06-14
2790 A temporal map of maternal immune activation-induced changes reveals a shift in neurodevelopmental timing and perturbed cortical development in mice.
Canales, C. P.; Estes, M. L.; Cichewicz, K.; Angara, K.; Aboubechara, J. P.; Cameron, S.; Prendergast, K.; Su-Feher, L. P.; Zdilar, I.; Kreun, E. J.; Connolly, E. C.; Seo, J. M.; Goon, J. B.; Farrelly, K.; Stradleigh, T.; van der List, D.; Haapanen, L.; Van de Water, J.; Vogt, D.; McAllister, A. K.; Nord, A. S.
10.1101/2020.06.13.150359 — neuroscience — Posted on 2020-06-14
2792 An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution
Howard, A. G. A.; Baker, P. A.; Ibarra-Garcia-Padilla, R.; Moore, J. A.; Rivas, L. J.; Singleton, E. W.; Westheimer, J. L.; Corteguera, J. A.; Tallman, J. J.; Uribe, R. A.
10.1101/2020.06.14.150938 — developmental biology — Posted on 2020-06-14
2795 The binding mechanism of Streptococcus suis accessory virulence factor and adhesin SadP to globotetraosylceramide
Johansson, M. M.; Belurier, E.; Papageorgiou, A. C.; Sundin, A. P.; Rahkila, J.; Kallonen, T.; Nilsson, U. J.; Maatsola, S.; Nyholm, T. K. M.; Käpylä, J.; Corander, J.; Leino, R.; Finne, J.; Teneberg, S.; Haataja, S. J.
10.1101/2020.05.29.122762 — microbiology — Posted on 2020-06-14
2798 In silico multi-epitope vaccine against covid19 showing effective interaction with HLA-B*15:03
Faiza, M.; Abdullah, T.; Calderon-Tantalean, J. F.; Upadhyay, M. R.; Abdelmoneim, A. H.; Akram, F.; Thakur, B. S.; Abdulaziz, I.; Ononamadu, C. J.; Ghoraba, D. A.; Munawar, S.; Faruque, M. F. I.; Kigen, C.; Sharma, A.; Kumar, A.; Khalid, A.; Gharip, A.; Gupta, A.; Manikumar, M.; Chaudhary, U.
10.1101/2020.06.10.143545 — bioinformatics — Posted on 2020-06-14
2799 Decoding the neural dynamics of oculomotor decision making in humans
Thiery, T.; Saive, A.-L.; Combrisson, E.; Dehgan, A.; Bastin, J.; Kahane, P.; Berthoz, A.; Lachaux, J.-P.; Jerbi, K.
10.1101/788091 — neuroscience — Posted on 2020-06-14
2803 SARS-CoV-2 Neutralizing Antibody Responses Are More Robust in Patients with Severe Disease
Wang, P.; Liu, L.; Nair, M. S.; Yin, M. T.; Luo, Y.; Wang, Q.; Yuan, T.; Mori, K.; Solis, A. G.; Yamashita, M.; Purpura, L. J.; Laracy, J. C.; Yu, J.; Sodroski, J.; Huang, Y.; Ho, D. D.
10.1101/2020.06.13.150250 — microbiology — Posted on 2020-06-14
2805 Single-cell screening of SARS-CoV-2 target cells in pets, livestock, poultry and wildlife
Chen, D.; Sun, J.; Zhu, J.; Ding, X.; Lan, T.; Zhu, L.; Xiang, R.; Ding, P.; Wang, H.; Wang, X.; Wu, W.; Qiu, J.; Wang, S.; Li, H.; An, F.; Bao, H.; Zhang, L.; Han, L.; Zhu, Y.; Wang, X.; Wang, F.; Yuan, Y.; Wu, W.; Sun, C.; Lu, H.; Wu, J.; Sun, X.; Zhang, S.; Sahu, S. K.; Chen, H.; Fang, D.; Luo, L.; Zeng, Y.; Wu, Y.; Cui, Z.; He, Q.; Jiang, S.; Ma, X.; Feng, W.; Xu, Y.; Li, F.; Liu, Z.; Chen, L.; Chen, F.; Jin, X.; Qiu, W.; Yang, H.; Wang, J.; Hua, Y.; Liu, Y.; Liu, H.; Xu, X.
10.1101/2020.06.13.149690 — cell biology — Posted on 2020-06-14
2807 SCIM: Universal Single-Cell Matching with Unpaired Feature Sets
Stark, S. G.; Ficek, J.; Locatello, F.; Bonilla, X.; Chevrier, S.; Singer, F.; Rätsch, G.; Lehmann, K.
10.1101/2020.06.11.146845 — bioinformatics — Posted on 2020-06-14
2808 A single-cell RNA-seq Training and Analysis Suite using the Galaxy Framework
Tekman, M.; Batut, B.; Ostrovsky, A.; Antoniewski, C.; Clements, D.; Ramirez, F.; Etherington, G. J.; Hotz, H.-R.; Scholtalbers, J.; Manning, J. R.; Bellenger, L.; Doyle, M. A.; Heydarian, M.; Huang, N.; Soranzo, N.; Moreno, P.; Mautner, S.; Papatheodorou, I.; Nekrutenko, A.; Taylor, J.; Blankenberg, D.; Backofen, R.; Grüning, B.
10.1101/2020.06.06.137570 — bioinformatics — Posted on 2020-06-14
2810 X-206 is a potent and selective inhibitor of SARS-CoV-2 infection in vitro
Svenningsen, E. B.; Jensen, J. T.; Cadanet, J. B.; Liu, H.; Lin, S.; Villameriel, J. M.; Paludan, S. R.; Holm, C. K.; Poulsen, T. B.
10.1101/2020.06.14.149153 — pharmacology and toxicology — Posted on 2020-06-14
2813 Mucoidy, a general mechanism for maintaining lytic phage in populations of bacteria
Chaudhry, W. N.; Lee, E.; Worthy, A.; Weiss, Z.; Grabowicz, M.; Vega, N.; Levin, B. R.
10.1101/775056 — microbiology — Posted on 2020-06-14
2816 Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics
Kotliar, D.; Lin, A. E.; Logue, J.; Hughes, T. K.; Khoury, N. M.; Raju, S. S.; Wadsworth, M. H.; Chen, H.; Kurtz, J. R.; Dighero-Kemp, B.; Bjornson, Z. B.; Mukherjee, N.; Sellers, B. A.; Tran, N.; Bauer, M. R.; Adams, G. C.; Adams, R.; Rinn, J. L.; Mele, M.; Nolan, G. P.; Barnes, K. G.; Hensley, L. E.; McIlwain, D. R.; Shalek, A. K.; Sabeti, P. C.; Bennett, R. S.
10.1101/2020.06.12.148957 — microbiology — Posted on 2020-06-14
2818 Variation in a pleiotropic hub gene drives morphological evolution: Insights from interspecific differences in head shape and eye size in Drosophila
Buchberger, E.; Bilen, A.; Ayaz, S.; Salamanca, D.; Matas de las Heras, C.; Niksic, A.; Almudi, I.; Torres-Oliva, M.; Casares, F.; Posnien, N.
10.1101/2020.01.24.918011 — evolutionary biology — Posted on 2020-06-14
2819 Climate explains geographic and temporal variation in mosquito-borne disease dynamics on two continents
Caldwell, J. M.; LaBeaud, A. D.; Lambin, E. F.; Stewart-Ibarra, A. M.; Ndenga, B. A.; Mutuku, F. M.; Krystosik, A. R.; Ayala, E. B.; Anyamba, A.; Borbor-Cordova, M. J.; Damoah, R.; Grossi-Soyster, E. N.; Heras Heras, F.; Ngugi, H. N.; Ryan, S. J.; Shah, M. M.; Sippy, R.; Mordecai, E. A.
10.1101/2020.02.07.938720 — ecology — Posted on 2020-06-14
2820 Cytoskeletal Tubulin Competes with Actin to Increase Deformability of Metastatic Melanoma Cells
Higgins, G.; Peres, J.; Abdalrahman, T.; Zaman, M. H.; Lang, D.; Prince, S.; Franz, T.
10.1101/2020.02.01.929919 — cancer biology — Posted on 2020-06-14
2825 Tumors induce de novo steroid biosynthesis in T cells to evade immunity
Mahata, B.; Pramanik, J.; Weyden, L. v. d.; Polanski, K.; Kar, G.; Riedel, A.; Chen, X.; Fonseca, N. A.; Kundu, K.; Campos, L. S.; Ryder, E.; Duddy, G.; Walczak, I.; Okkenhaug, K.; Adams, D. J.; Shields, J. D.; Teichmann, S. A.
10.1101/471359 — immunology — Posted on 2020-06-14
2827 LAYNII: A software suite for layer-fMRI
Huber, L.; Poser, B. A.; Bandettini, P. A.; Arora, K.; Wagstyl, K.; Cho, S.; Goense, J.; Nothnagel, N.; Morgan, A. T.; van den Hurk, J.; Reynolds, R. C.; Glen, D. R.; Goebel, R. W.; Gulban, O. F.
10.1101/2020.06.12.148080 — neuroscience — Posted on 2020-06-14
2830 A circulating T-cell differentiation marker to predict response to immune checkpoint inhibitors
Yamauchi, T.; Hoki, T.; Oba, T.; Jain, V.; Chen, H.; Attwood, K.; Battaglia, S.; George, S.; Chatta, G.; Puzanov, I.; Morrison, C.; Odunsi, K.; Segal, B. H.; Dy, G. K.; Ernstoff, M. S.; Ito, F.
10.1101/2020.06.13.095844 — immunology — Posted on 2020-06-14
2832 Protein Profiles: Biases and Protocols
Urban, G.; Torrisi, M.; Magnan, C.; Pollastri, G.; Baldi, P.
10.1101/2020.06.13.148718 — bioinformatics — Posted on 2020-06-14
2834 Brain-predicted age associates with psychopathology dimensions in youth
Cropley, V.; Tian, Y.; Fernando, K.; Mansour, S.; Pantelis, C.; Cocchi, L.; Zalesky, A.
10.1101/2020.06.13.149658 — neuroscience — Posted on 2020-06-14
2835 A comprehensive framework for handling location error in animal tracking data
Fleming, C. H.; Drescher-Lehman, J.; Noonan, M. J.; Akre, T. S. B.; Brown, D. J.; Cochrane, M. M.; Dejid, N.; DeNicola, V.; DePerno, C. S.; Dunlop, J. N.; Gould, N. P.; Hollins, J.; Ishii, H.; Kaneko, Y.; Kays, R.; Killen, S. S.; Koeck, B.; Lambertucci, S. A.; LaPoint, S. D.; Medici, E. P.; Meyburg, B.-U.; Miller, T. A.; Moen, R. A.; Mueller, T.; Pfeiffer, T.; Pike, K. N.; Roulin, A.; Safi, K.; Sechaud, R.; Scharf, A. K.; Shephard, J. M.; Stabach, J. A.; Stein, K.; Tonra, C. M.; Yamazaki, K.; Fagan, W. F.; Calabrese, J. M.
10.1101/2020.06.12.130195 — ecology — Posted on 2020-06-14
2836 MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis
Kantar, D.; Bousquet Mur, E.; Slaninova, V.; Ben Salah, Y.; Costa, L.; Forest, E.; Lassus, P.; Geminard, C.; Larroque, M.; Boissiere-Michot, F.; Orsetti, B.; Theillet, C.; Colinge, J.; Benistant, C.; Maraver, A.; Heron-Milhavet, L.; Djiane, A.
10.1101/2020.06.13.149724 — cancer biology — Posted on 2020-06-14
2839 Phase separation induced by cohesin SMC protein complexes
Ryu, J.-K.; Bouchoux, C.; Liu, H. W.; Kim, E.; Minamino, M.; de Groot, R.; Katan, A. J.; Bonato, A.; Marenduzzo, D.; Michieletto, D.; Uhlmann, F.; Dekker, C.
10.1101/2020.06.13.149716 — biophysics — Posted on 2020-06-14
2843 Diversity increases yield but reduces reproductive effort in crop mixtures
Chen, J.; Engbersen, N.; Stefan, L.; Schmid, B.; Sun, H.; Schob, C.
10.1101/2020.06.12.149187 — ecology — Posted on 2020-06-14
2844 Reply to Li et al. "Is Oculudentavis a bird or even archosaur?"
O'Connor, J.; Xing, L.; Chiappe, L.; Schmitz, L.; McKellar, R.; Li, G.; Yi, Q.
10.1101/2020.06.12.147041 — paleontology — Posted on 2020-06-14
2851 Specific ZNF274 binding interference at SNORD116 activates the maternal transcripts in Prader-Willi syndrome neurons
Langouet, M.; Gorka, D.; Orniacki, C.; Dupont-Thibert, C. M.; Chung, M. S.; Glatt-Deeley, H. R.; Germain, N.; Crandall, L. J.; Cotney, J. L.; Stoddard, C. E.; Lalande, M.; Chamberlain, S. J.
10.1101/2020.06.13.149864 — genetics — Posted on 2020-06-14
2854 Three-dimensional analysis and visualization of morphological adaptations associated with viviparity in the Tsetse fly (Glossina morsitans).
Attardo, G. M.; Tam, N. B.; Parkinson, D. Y.; Mack, L. K.; Zahnle, X. J.; Arguellez, J.; Takac, P.; Malacrida, A. R.
10.1101/2020.06.12.147587 — physiology — Posted on 2020-06-14
2856 Prrx1b directs pro-regenerative fibroblasts during zebrafish heart regeneration
de Bakker, D. E. M.; Dronkers, E.; Bouwman, M.; Vink, A.; Goumans, M.-J.; Smits, A. M.; Bakkers, J.
10.1101/2020.06.13.149013 — developmental biology — Posted on 2020-06-14
2857 Cohesin residency determines chromatin loop patterns
Costantino, L.; Hsieh, T.-H. S.; Lamothe, R.; Darzacq, X. D.; Koshland, D. E.
10.1101/2020.06.11.146902 — genomics — Posted on 2020-06-14
2858 Dendritic cell actin dynamics controls T cell priming efficiency at the immunological synapse
Leithner, A.; Altenburger, L. M.; Hauschild, R.; Assen, F.; Rottner, K.; Stradal, T. E. B.; Stein, J. V.; Sixt, M.
10.1101/2020.06.13.150045 — cell biology — Posted on 2020-06-14
2859 STEADY-STATE REGULATION OF SECRETORY CARGO EXPORT BY INOSITOL TRISPHOSPHATE RECEPTORS AND PENTA EF HAND PROTEINS
Held, A.; Hojanazarova, J.; Sargeant, J.; Madreiter-Sokolowski, C.; Mali, R.; Graier, W. F.; Hay, J. C.
10.1101/2020.06.13.150144 — cell biology — Posted on 2020-06-14
2861 Autoregulatory control of microtubule binding in the oncogene, doublecortin-like kinase 1
Rogers, M. M.; Ramkumar, A.; Downing, A. M.; Bodin, H.; Castro, J.; Nowakowski, D. W.; Ori-McKenney, K. M.
10.1101/2020.06.12.149252 — biochemistry — Posted on 2020-06-14
2865 Bacterial protein domains with a novel Ig-like fold bind human CEACAM receptors
van Sorge, N. M.; Bonsor, D. A.; Deng, L.; Lindahl, E.; Schmitt, V.; Lyndin, M.; Schmidt, A.; Nilsson, O. R.; Brizuela, J.; Boero, E.; Sundberg, E. J.; van Strijp, J.; Doran, K. S.; Singer, B. S.; Lindahl, G.; McCarthy, A. J.
10.1101/2020.06.09.141622 — microbiology — Posted on 2020-06-14
2866 Heat Shock Protein 27 versus Estrogen Therapy for Post-Menopausal Atherosclerosis: Rethinking Mechanisms of Cholesterol Lowering
Maarouf, N.; Chen, Y.-X.; Shi, C.; Deng, J.; Diao, C.; Rosin, M.; Shrivastava, V.; Batulan, Z.; Liu, J.; O'Brien, E. R.
10.1101/2020.06.04.135483 — pathology — Posted on 2020-06-13
2867 Neuroendocrine mechanisms governing sex-differences in chronic pain involve prolactin receptor sensory neuron signaling
Paige, C.; Barba-Escobedo, P. A.; Mecklenburg, J.; Patil, M.; Goffin, V.; Grattan, D.; Dussor, G.; Akopian, A. N.; Price, T. J.
10.1101/2020.04.25.061663 — neuroscience — Posted on 2020-06-14
2868 Drift and termination of spiral waves in optogenetically-modified cardiac tissue at sub-threshold illumination
Hussaini, S.; Venkatesan, V.; European Laboratory for Non-Linear Spectroscopy, ; McGill University, ; Quinonez Uribe, R. A.; Richter, C.; Krinski, V.; Parlitz, U.; Majumder, R.; Luther, S.
10.1101/2020.06.12.148734 — biophysics — Posted on 2020-06-13
2870 Integrated gut-liver-on-a-chip platform as an in vitro human model of non-alcoholic fatty liver disease
Yang, J.; Hirai, Y.; Iida, K.; Ito, S.; Trumm, M.; Terada, S.; Sakai, R.; Tsuchiya, T.; Tabata, O.; Kamei, K.-i.
10.1101/2020.06.10.141606 — bioengineering — Posted on 2020-06-13
2872 Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease
Butkovich, L. M.; Houser, M. C.; Chalermpalanupap, T.; Porter-Stransky, K.; Iannitelli, A.; Boles, J. S.; LLoyd, G. M.; Coomes, A.; Eidson, L. N.; DeSousa Rodrigues, M. E.; Olivefr, D. L.; Kelly, S. D.; Chang, J.; Bengoa-Vergniory, N.; Wade-Martins, R.; Weinshenker, D.; Giasson, B. I.; Joers, V.; Tansey, M. G.
10.1101/857987 — neuroscience — Posted on 2020-06-13
2874 The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy
Thawani, A.; Rale, M. J.; Coudray, N.; Bhabha, G.; Stone, H. A.; Shaevitz, J. W.; Petry, S.
10.1101/853010 — cell biology — Posted on 2020-06-13
2877 Neurotransmitter Classification from Electron Microscopy Images at Synaptic Sites in Drosophila
Eckstein, N.; Bates, A. S.; Du, M.; Hartenstein, V.; Jefferis, G. S. X. E.; Funke, J.
10.1101/2020.06.12.148775 — neuroscience — Posted on 2020-06-13
2879 SARS-CoV-2 Spike Glycoprotein and ACE2 interaction reveals modulation of viral entry in different hosts
Praharaj, M. R.; Garg, P.; Khan, R. I. N.; Sharma, S.; Panigrahi, M.; Mishra, B. P.; Mishra, B.; Kumar, G. S.; Gandham, R. K.; Singh, R. K.; Majumdar, S.; Mohapatra, T.
10.1101/2020.05.08.084327 — microbiology — Posted on 2020-06-13
2881 Analysis of Infected Host Gene Expression Reveals Repurposed Drug Candidates and Time-Dependent Host Response Dynamics for COVID-19
Xing, J.; Shankar, R.; Drelich, A.; Paithankar, S.; Chekalin, E.; Dexheimer, T.; Chua, M.-S.; Rajasekaran, S.; Tseng, C.-T. K.; Chen, B.
10.1101/2020.04.07.030734 — genomics — Posted on 2020-06-13
2884 Targeted disruption of Pparγ1 promotes trophoblast endoreplication in the murine placenta
Nakano, T.; Aochi, H.; Hirasaki, M.; Takenaka, Y.; Fujita, K.; Soma, H.; Kamezawa, H.; Koizumi, T.; Okuda, A.; Murakoshi, T.; Shimada, A.; Inoue, I.
10.1101/2020.05.28.120691 — developmental biology — Posted on 2020-06-13
2886 Microengineered three-dimensional collagen landscapes with independently tunable fiber anisotropy and directionality
Ahmed, A.; Joshi, I. M.; Larson, S.; Gholizadeh, S.; Borkholder, D. A.; Gaborski, T. R.; Abhyankar, V. V.
10.1101/2020.06.12.148346 — bioengineering — Posted on 2020-06-13
2888 Cholesterol rich, highly phase separated, naked mole-rat brain lipids are exquisitely sensitive to amyloid induced membrane damage
FRANKEL, D.; St John Smith, E.; Rankin, K.; Cenac, N.; Davies, M.; Kumita, J. R.; Vendruscolo, M.; Kulaberoglu, Y.; Urriola Munoz, P.; Bertrand-michel, J.; Preet, S.; Smith, A.; Bhushan, B.
10.1101/2020.06.05.134973 — biophysics — Posted on 2020-06-13
2889 GEM: Scalable and flexible gene-environment interaction analysis in millions of samples
Westerman, K. E.; Pham, D. T.; Hong, L.; Chen, Y.; Sevilla-Gonzalez, M.; Sung, Y. J.; Sun, Y. V.; Morrison, A.; Chen, H.; Manning, A. K.
10.1101/2020.05.13.090803 — bioinformatics — Posted on 2020-06-13
2890 An opened pre-40S platform enables temporal regulation of Fap7
Rai, J.; Parker, M. D.; Huang, H.; Choi, S.; Ghalei, H.; Johnson, M. C.; Karbstein, K.; Stroupe, M. E.
10.1101/617910 — biochemistry — Posted on 2020-06-13
2891 Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity
Ikegame, S.; Beaty, S. M.; Stevens, C.; Won, T. S.; Park, A.; Sachs, D.; Hong, P.; Thibault, P. A.; Lee, B.
10.1101/2020.03.30.016493 — microbiology — Posted on 2020-06-13
2892 Macrophages can inhibit and enhance endometriosis depending on their origin
Hogg, C.; Dhami, P.; Rosser, M.; Mack, M.; Soong, D.; Pollard, J. W.; Jenkins, S. J.; Horne, A. W.; Greaves, E.
10.1101/2020.04.30.070003 — immunology — Posted on 2020-06-13
2893 In situ structure of the AcrAB-TolC efflux pump at subnanometer resolution
Chen, M.; Shi, X.; Yu, Z.; Fan, G.; Serysheva, I. I.; Baker, M.; Luisi, B.; Ludtke, S.; Wang, Z.
10.1101/2020.06.10.144618 — biophysics — Posted on 2020-06-13
2899 Expanding the diversity of bacterioplankton isolates and modeling isolation efficacy with large scale dilution-to-extinction cultivation
Henson, M. W.; Lanclos, V. C.; Pitre, D. M.; Weckhorst, J. L.; Lucchesi, A. M.; Cheng, C.; Temperton, B.; Thrash, C.
10.1101/2020.04.17.046896 — microbiology — Posted on 2020-06-13
2901 Supersized ribosomal RNA expansion segments in Asgard archaea
Penev, P. I.; Fakhretaha-Aval, S.; Patel, V. J.; Cannone, J. J.; Gutell, R. R.; Petrov, A. S.; Williams, L. D.; Glass, J. B.
10.1101/2019.12.25.888164 — evolutionary biology — Posted on 2020-06-13
2903 ROBOCOV: An affordable open-source robotic platform for COVID-19 testing by RT-qPCR
Villanueva-Canas, J. L.; Gonzalez-Roca, E.; Gastaminza Unanue, A.; Titos, E.; Martinez Yoldi, M. J.; Vergara Gomez, A.; Puig Butille, J. A.
10.1101/2020.06.11.140285 — bioinformatics — Posted on 2020-06-13
2905 Microbial Diversity of Deep-Sea Ferromanganese Crust Field in the Rio Grande Rise, Southwestern Atlantic Ocean
Bergo, N. M.; Bendia, A. G.; Ferreira, J. C. N.; Murton, B. J.; Brandini, F. P.; Pellizari, V. H.
10.1101/2020.06.13.150011 — microbiology — Posted on 2020-06-13
2907 ELECTRO-STERIC MECHANISM OF CLC-2 CHLORIDE CHANNEL ACTIVATION
De Jesus-Perez, J. J.; Mendez-Maldonado, G. A.; Gonzalez-Hernandez, I. L.; De la Rosa, V.; Gastelum-Garibaldi, R.; Sanchez-Rodriguez, J. E.; Arreola, J.
10.1101/2020.06.12.148783 — physiology — Posted on 2020-06-13
2909 Host porphobilinogen deaminase deficiency confers malaria resistance in Plasmodium chabaudi but not in Plasmodium falciparum or Plasmodium berghei during intraerythrocytic growth
Schnider, C. B.; Yang, H.; Starrs, L.; Ehmann, A.; Rahimi, F.; Di Pierro, E.; Graziadei, G.; Matthews, K.; de Koning-Ward, T.; Bauer, D. C.; Foote, S.; Burgio, G.; McMorran, B.
10.1101/589242 — microbiology — Posted on 2020-06-13
2910 Bacteria on steroids: the enzymatic mechanism of an NADH-dependent dehydrogenase that regulates the conversion of cortisol to androgen in the gut microbiome
Bernardi, R. C.; Doden, H. L.; Melo, M. C. R.; Devendran, S.; Pollet, R. M.; Mythen, S. M.; Bhowmik, S.; Lesley, S. A.; Cann, I.; Luthey-Schulten, Z.; Koropatkin, N. M.; Ridlon, J. M.
10.1101/2020.06.12.149468 — microbiology — Posted on 2020-06-13
2911 Structural and Functional Implications of Spike Protein Mutational Landscape in SARS-CoV-2
Nelson-Sathi, S.; Umasankar, P. K.; Easwaran, S.; Nair, R. R.; Joseph, I.; Nori, S. R. C.; Philip, J. S.; Prasad, R.; Navyasree, K. V.; Ramesh, S.; Pillai, H.; Gosh, S.; TR, S. K.; Pillai, M. R.
10.1101/2020.05.02.071811 — evolutionary biology — Posted on 2020-06-13
2912 Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
Gowrishankar, S.; Lyons, L.; Rafiq, N. M.; Roczniak-Ferguson, A.; De Camilli, P.; Ferguson, S.
10.1101/2020.06.13.149443 — cell biology — Posted on 2020-06-13
2913 Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth.
Geeraerts, S. L.; Kampen, K. R.; Rinaldi, G.; Gupta, P.; Planque, M.; De Cremer, K.; De Brucker, K.; Vereecke, S.; Verbelen, B.; Vermeersch, P.; Cassiman, D.; Fendt, S.-M.; Voet, A.; Cammue, B. P. A.; Thevissen, K.; De Keersmaecker, K.
10.1101/2020.06.12.148395 — cancer biology — Posted on 2020-06-13
2916 Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data
Blumberg, A.; Zhao, Y.; Huang, Y.-F.; Dukler, N.; Rice, E. J.; Chivu, A. G.; Krumholz, K.; Danko, C. G.; Siepel, A.
10.1101/690644 — genomics — Posted on 2020-06-13
2919 Ethylene-triggered subcellular trafficking of CTR1 suppresses the response to ethylene gas
Lee, H. Y.; Seo, D. H.; Bakshi, A.; Park, H. L.; Park, C.; Kieber, J. J.; Binder, B. M.; Yoon, G.
10.1101/2020.06.12.148858 — plant biology — Posted on 2020-06-13
2922 Mendelian randomisation study exploring the associations of serum folate with pan and site-specific cancers
Burrows, K.; Kazmi, N.; Haycock, P.; Tsilidis, K. K.; PRACTICAL consortium, CRUK, BPC3, CAPS and PEGASUS, ; GECCO, CORECT and CCFR, ; Martin, R. M.; Lewis, S. J.
10.1101/762138 — genomics — Posted on 2020-06-13
2923 The Portal Project: a long-term study of a Chihuahuan desert ecosystem
Ernest, S. M.; Yenni, G. M.; Allington, G.; Bledsoe, E.; Christensen, E.; Diaz, R.; Geluso, K.; Goheen, J.; Guo, Q.; Heske, E.; Kelt, D.; Meiners, J.; Munger, J.; Restrepo, C.; Samson, D.; Schutzenhofer, M.; Skupski, M.; Supp, S.; Thibault, K.; Taylor, S.; White, E.; Ye, H.; Davidson, D.; Brown, J. H.; Valone, T. J.
10.1101/332783 — ecology — Posted on 2020-06-13
2927 Allelic Variation of MYB10 is the Major Force Controlling Natural Variation of Skin and Flesh Color in Strawberry (Fragaria spp.) fruit
Castillejo, C.; Waurich, V.; Wagner, H.; Ramos, R.; Oiza, N.; Munoz, P.; Trivino, J. C.; Caruana, J.; Liu, Z.; Cobo, N.; Hardigan, M. A.; Knapp, S. J.; Vallarino, J. G.; Osorio, S.; Martin-Pizarro, C.; Pose, D.; Toivainen, T.; Hytonen, T.; Oh, Y.; Barbey, C.; Whitaker, V. M.; Lee, S.; Olbricht, K.; Sanchez-Sevilla, J. F.; Amaya, I.
10.1101/2020.06.12.148015 — plant biology — Posted on 2020-06-13
2929 Auditory aversion in absolute pitch possessors
Rogenmoser, L.; Li, C. H.; Jancke, L.; Schlaug, G.
10.1101/2020.06.13.145029 — neuroscience — Posted on 2020-06-13
2930 CK2 inhibits TIMELESS nuclear export and modulates CLOCK transcriptional activity to regulate circadian rhythms
Cai, Y. D.; Xue, Y.; Truong, C.; Del-Carmen Li, J.; Ochoa, C.; Vanselow, J. T.; Murphy, K. A.; Li, Y. H.; Liu, X.; Kunimoto, B. L.; Zheng, H.; Zhao, C.; Zhang, Y.; Schlosser, A.; Chiu, J. C.
10.1101/2020.06.12.148825 — neuroscience — Posted on 2020-06-13
2932 Degradation of Lon in Caulobacter crescentus
Barros, B. B.; Mahmoud, S. A.; Chien, P.; Zeinert, R. D.
10.1101/2020.06.12.149492 — microbiology — Posted on 2020-06-13
2933 Cellular and Cytokine Responses in the Granulomas of Asymptomatic Cattle naturally infected with Mycobacterium bovis in Ethiopia
Tulu, B.; Martineau, H.; Zewude, A.; Desta, F.; Jolliffe, D. A.; Abebe, M.; Tolera, T.; Belay, M.; Martineau, A.; Ameni, G.
10.1101/2020.06.12.149518 — immunology — Posted on 2020-06-13
2934 Comparative genomics of Chlamydomonas
Craig, R. J.; Hasan, A. R.; Ness, R. W.; Keightley, P. D.
10.1101/2020.06.13.149070 — genomics — Posted on 2020-06-13
2935 Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution
Huddleston, J.; Barnes, J. R.; Rowe, T.; Kondor, R.; Wentworth, D. E.; Whittaker, L.; Ermetal, B.; Daniels, R. S.; McCauley, J. W.; Fujisaki, S.; Nakamura, K.; Kishida, N.; Watanabe, S.; Hasegawa, H.; Barr, I.; Subbarao, K.; Neher, R.; Bedford, T.
10.1101/2020.06.12.145151 — evolutionary biology — Posted on 2020-06-13
2936 Ultra-rapid metagenotyping of the human gut microbiome
Shi, Z. J.; Dimitrov, B.; Zhao, C.; Nayfach, S.; Pollard, K. S.
10.1101/2020.06.12.149336 — bioinformatics — Posted on 2020-06-13
2939 CDC6 regulates mitotic CDK1 via cyclin B and not cyclin A and acts through a bona fide CDK inhibitor Xic1
Kubiak, J. Z.; El Dika, M.; Wechselberger, L.; Djeghout, B.; Benouareth, D. E.; Jederka, K.; Lewicki, S.; Prigent, C.; Kloc, M.
10.1101/2020.06.13.149989 — cell biology — Posted on 2020-06-13
2940 Structure of the cysteine-rich domain of Plasmodium falciparum P113 identifies the location of the RH5 binding site
Campeotto, I.; Galaway, F.; Mehmood, S.; Barfod, L.; Quinkert, D.; Kotraiah, V.; Phares, T. W.; Wright, K. E.; Snijders, A. P.; Draper, S. J.; Higgins, M.; Wright, G. J.
10.1101/2020.06.12.149534 — microbiology — Posted on 2020-06-13
2941 DeepEMhacer: a deep learning solution for cryo-EM volume post-processing
Sanchez Garcia, R.; Gomez-Blanco, J.; Cuervo, A.; Carazo, J. M.; Sorzano, C. O. S.; Vargas, J.
10.1101/2020.06.12.148296 — bioinformatics — Posted on 2020-06-13
2942 Cystal structure of inhibitor-bound human MSPL/TMPRSS13 that can activate high pathogenic avian influenza
Ohno, A.; Maita, N.; Tabata, T.; Nagano, H.; Arita, K.; Ariyoshi, M.; Uchida, T.; Nakao, R.; Ulla, A.; Sugiura, K.; Kishimoto, K.; Teshima-Kondo, S.; Nikawa, T.; Okumura, Y.
10.1101/2020.06.12.149229 — biophysics — Posted on 2020-06-13
2943 Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon
Finney, L. J.; Glanville, N.; Farne, H.; Aniscenko, J.; Fenwick, P.; Kemp, S.; Trujillo-Torralbo, M.-B.; Calderazzo, M.; Wedzicha, J. A.; Mallia, P.; Bartlett, N. W.; Johnston, S. L.; Singanayagam, A.
10.1101/2020.06.13.149039 — immunology — Posted on 2020-06-13
2944 Colon Cancer and SARS-CoV-2: Impact of ACE2 Expression in Susceptibility to COVID-19
Ahmadi, M.; Saffarzadeh, N.; Amin Habibi, M.; Hajiesmaeili, F.; Rezaei, N.
10.1101/2020.06.11.146878 — genetics — Posted on 2020-06-13
2945 Multi-epitope Based Peptide Vaccine Design Using Three Structural Proteins (S, E, and M) of SARS-CoV-2: An In Silico Approach
Roy, A. S.; Quadery Tonmoy, M. I.; Fariha, A.; Hami, I.; Khalil Afif, I.; Munim, M. A.; Alam, M. R.; Hossain, M. S.
10.1101/2020.06.13.149880 — bioinformatics — Posted on 2020-06-13
2946 Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics
Kotliar, D.; Lin, A. E.; Logue, J.; Hughes, T. K.; Khoury, N. M.; Raju, S. S.; Wadsworth, M. H.; Chen, H.; Kurtz, J. R.; Dighero-Kemp, B.; Bjornson, Z. B.; Mukherjee, N.; Sellers, B. A.; Tran, N.; Bauer, M. R.; Adams, G. C.; Adams, R.; Rinn, J. L.; Mele, M.; Nolan, G. P.; Barnes, K. G.; Hensley, L. E.; McIlwain, D. R.; Shalek, A. K.; Sabeti, P. C.; Bennett, R. S.
10.1101/2020.06.12.148957 — microbiology — Posted on 2020-06-13
2947 Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
Zhou, D.; Duyvesteyn, H. M. E.; Chen, C.-P.; Huang, C.-G.; Chen, T.-H.; Shih, S.-R.; Lin, Y.-C.; Cheng, C.-Y.; Cheng, S.-H.; Huang, Y.-C.; Lin, T.-Y.; Ma, C.; Huo, J.; Carrique, L.; Malinauskas, T.; Ruza, R. R.; Shah, P.; Tan, T. K.; Rijal, P.; Donat, R. F.; Godwin, K.; Buttigieg, K.; Tree, J.; Radecke, J.; Paterson, N. G.; Supasa, P.; Mongkolsapaya, J.; Screaton, G. R.; Carroll, M. W.; Jaramillo, J. G.; Knight, M.; James, W. S.; Owens, R. J.; Naismith, J. H.; Townsend, A.; Fry, E. E.; Zhao, Y.; Ren, J.; Stuart, D. I.; Huang, K.-Y. A.
10.1101/2020.06.12.148387 — microbiology — Posted on 2020-06-13
2948 Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4+ T cells
Meckiff, B. J.; Ramirez-Suastegui, C.; Fajardo, V.; Chee, S. J.; Kusnadi, A.; Simon, H.; Grifoni, A.; Pelosi, E.; Weiskopf, D.; Sette, A.; Ay, F.; Seumois, G.; Ottensmeier, C.; Vijayanand, P.
10.1101/2020.06.12.148916 — immunology — Posted on 2020-06-13
2949 WHOLE-GENOME SEQUENCING AND DE NOVO ASSEMBLY OF A 2019 NOVEL CORONAVIRUS (SARS-COV-2) STRAIN ISOLATED IN VIETNAM
Le, L. T.; Nguyen, H. T.; Nguyen, T. H.; Ho, T. T.; Tran, L. H.; Luu, T. T.; Nguyen, T. T. N.; Huynh, L. T. K.; Pham, Q. D.; Luong, Q. C.; Cao, T. M.; Nguyen, T. V.; Hoang, H.; Chu, H. H.; Phan, L. T.; Truong, H. N.
10.1101/2020.06.12.149377 — genomics — Posted on 2020-06-13
2955 Immunoresolvents Support Skeletal Myofiber Regeneration via Actions on Myeloid and Muscle Stem Cells
Markworth, J. F.; Brown, L. A.; Lim, E.; Floyd, C.; Larouche, J.; Castor-Macias, J. A.; Sugg, K. B.; Sarver, D. C.; Macpherson, P. C. F.; Davis, C.; Aguilar, C. A.; Maddipati, K. R.; Brooks, S. V.
10.1101/2020.06.12.148320 — immunology — Posted on 2020-06-13
2958 Ranking microbial metabolomic and genomic links using correlation-based and feature-based scoring functions
Hjorleifsson Eldjarn, G.; Ramsey, A.; van der Hooft, J. J. J.; Duncan, K. R.; Soldatou, S.; Rousu, J.; Rogers, S.
10.1101/2020.06.12.148205 — systems biology — Posted on 2020-06-13
2962 Competition NMR for Detection of Hit/Lead Inhibitors of Protein-Protein Interactions
Musielak, B.; Janczyk, W.; Plewka, J.; Rodriguez, I.; Sala, D.; Magiera-Mularz, K.; Holak, T.
10.1101/2020.06.12.148379 — biophysics — Posted on 2020-06-13
2965 Heart Slice Culture System Reliably Demonstrates Clinical Drug-Related Cardiotoxicity
Miller, J. M.; Meki, M. H.; Ou, Q.; George, S. A.; Gams, A.; Abouleisa, R. R. E.; Tang, X.-L.; Ahern, B. M.; Giridharan, G. A.; El-Baz, A.; Hill, B. G.; Satin, J.; Conklin, D. J.; Moslehi, J.; Bolli, R.; Ribeiro, A. J. S.; Efimov, I. R.; Mohamed, T. M. A.
10.1101/2020.06.12.148197 — cell biology — Posted on 2020-06-13
2966 ALX1-related Frontonasal Dysplasia Results From Defective Neural Crest Cell Development and Migration
Pini, J.; Kueper, J.; Hu, Y.; Kawasaki, K.; Yeung, P.; Tsimbal, C.; Yoon, B.; Carmichael, N.; Maas, R.; Cotney, J.; Grinblat, J.; Liao, E. C.
10.1101/2020.06.12.148262 — cell biology — Posted on 2020-06-13
2967 Microtubules regulate pancreatic beta cell heterogeneity via spatiotemporal control of insulin secretion hot spots
Trogden, K. P.; McKinney, H.; Zhu, X.; Arpag, G.; Folland, T. G.; Osipovich, A. B.; Magnuson, M. A.; Zanic, M.; Gu, G.; Holmes, W. R.; Kaverina, I.
10.1101/2020.06.12.148668 — cell biology — Posted on 2020-06-13
2969 PP2A:B56 Regulates Meiotic Chromosome Segregation in C. elegans Oocytes
Bel Borja, L.; Soubigou, F.; Taylor, S. J. P.; Fraguas Bringas, C.; Budrewicz, J.; Lara-Gonzalez, P.; Sorensen-Turpin, C. G.; Bembenek, J. N.; Cheerambathur, D. K.; Pelisch, F.
10.1101/2020.06.12.148254 — cell biology — Posted on 2020-06-13
2970 Overhauling a faulty control in the CDC-recommended SARS-CoV-2 RT-PCR test
Dekker, R. J.; Ensink, W. A.; van Leeuwen, S.; Rauwerda, H.; Breit, T. M.
10.1101/2020.06.12.147819 — microbiology — Posted on 2020-06-13
2971 Nuclear deformation causes DNA damage by increasing replication stress
Shah, P.; Cheng, S.; Hobson, C. M.; Colville, M. J.; Paszek, M.; Superfine, R.; Lammerding, J.
10.1101/2020.06.12.148890 — cell biology — Posted on 2020-06-13
2972 Glycocalyx-mediated Cell Adhesion and Migration
Schmidt, S.; Weigelin, B.; te Riet, J.; te Boekhorst, V.; te Lindert, M.; Wijers-Rouw, M.; Lelli, B.; Rognoni, L.; Krause-Vortmeyer, M.; Messent, A.; Bracci, L.; Gottschalk, K. E.; Kissler, S.; Humphries, M.; Lefeber, D. J.; Fransen, J.; Friedl, P.
10.1101/2020.06.12.149096 — cell biology — Posted on 2020-06-13
2974 Reduction in CD11c+ microglia promotes secondary progression in autoimmune demyelination
Chechneva, O.; Mayrhofer, F.; Dariychuk, Z.; Zhen, A.; Daugherty, D. J.; Bannerman, P.; Hanson, A. M.; Pleasure, D. E.; Soulika, A.; Deng, W.
10.1101/396036 — neuroscience — Posted on 2020-06-13
2975 Ush regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis
Lenz, J.; Liefke, R.; Funk, J.; Shoup, S.; Nist, A.; Stiewe, T.; Schulz, R.; Tokusumi, Y.; Albert, L.; Raifer, H.; Förstemann, K.; Vazquez, O.; Tokusumi, T.; Fossett, N.; Brehm, A.
10.1101/2020.06.10.143701 — molecular biology — Posted on 2020-06-13
2976 Binding of Leishmania infantum LPG to the midgut is not sufficient to define vector competence in Lutzomyia longipalpis sand flies
Coutinho-Abreu, I. V.; Oristian, J.; de Castro, W.; Wilson, T. R.; Meneses, C.; Soares, R. P.; Borges, V. M.; Descoteaux, A.; Kamhawi, S.; Valenzuela, J.
10.1101/2020.06.10.145342 — microbiology — Posted on 2020-06-13
2978 Convergence of cortical types and functional motifs in the mesiotemporal lobe
Paquola, C.; Benkarim, O.; DeKraker, J.; Lariviere, S.; Frassle, S.; Royer, J.; Tavakol, S.; Valk, S. L.; Bernasconi, A.; Bernasconi, N.; Khan, A.; Evans, A. C.; Razi, A.; Smallwood, J.; Bernhardt, B.
10.1101/2020.06.12.148643 — neuroscience — Posted on 2020-06-13
2981 APP binds to the EGFR ligands HB-EGF and EGF, acting synergistically with EGF to promote ERK signaling and neuritogenesis
da Rocha, J. F.; Bastos, L.; Domingues, S. C.; Bento, A. R.; Konietzko, U.; da Cruz e Silva, O. A. B.; Vieira, S. I.
10.1101/2020.06.12.149062 — neuroscience — Posted on 2020-06-13
2983 Pandora: 4-D white matter bundle population-based atlasesderived from diffusion MRI fiber tractography
Hansen, C. B.; Yang, Q.; Lyu, I.; Rheault, F.; Kerley, C.; Chandio, B. Q.; Fadnavis, S.; Williams, O.; Shafer, A. T.; Resnick, S. M.; Zald, D. H.; Cutting, L.; Taylor, W. D.; Boyd, B.; Garyfallidis, E.; Anderson, A. W.; Descoteaux, M.; Landman, B. A.; Schilling, K.
10.1101/2020.06.12.148999 — neuroscience — Posted on 2020-06-13
2986 Right lateralized posterior parietal theta-gamma coupling during sustained attention in mice
Yang, R.; Dunbar, C.; Sonesra, A.; Park, S.; Pham, T.; Samaco, R.; Foster, B.; Maheshwari, A.
10.1101/2020.06.11.147330 — neuroscience — Posted on 2020-06-12
2989 Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling
de Lange, A.; Prodjinotho, F.; Tomes, H.; Hagen, J.; Jacobs, B.-A.; Smith, K.; Horsnell, W.; Sikasunge, C.; Selkirk, M. E.; Prazeres da Costa, C.; Raimondo, J. V.
10.1101/2020.06.12.148007 — neuroscience — Posted on 2020-06-12
2991 Whole genome sequencing of global Spodoptera frugiperda populations: evidence for complex, multiple introductions across the Old World
Tay, W. T.; Rane, R.; Padovan, A.; Walsh, T.; Elfekih, S.; Downes, S.; Nam, K.; d'Alencon, E.; Zhang, J.; Wu, Y.; Negre, N.; Kunz, D.; Kriticos, D. J.; Czepak, C.; Otim, M. H.; Gordon, K. H.
10.1101/2020.06.12.147660 — genomics — Posted on 2020-06-12
2992 A systematic review of European farmer and non-farmer attitudes towards landscapes, ecosystem services, and agricultural management practices: Implications for permanent grassland management.
Tindale, S. J.; Elliott, J.; Elings, M.; Gallardo-Cobos, R.; Hunter, E.; Lieberherr, E.; Miskolci, S.; Newell Price, P.; Quatrini, S.; Sanchez-Zamora, P.; Schleuter, H.; Frewer, L. J.
10.1101/2020.06.12.148585 — ecology — Posted on 2020-06-12
2996 DNA glycosylase NEIL2 prevents Fusobacterium-mediated inflammation and DNA damage in colonic epithelial cells
Sayed, I.; Chakraborty, A.; Ali, A.; Sharma, A.; Sahan, A.; Sahoo, D.; Ghosh, P.; Hazra, T.; Das, S.
10.1101/2020.06.11.147454 — immunology — Posted on 2020-06-12
2997 Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells
Wong, C.; Darby, J. M.; Murphy, P. R.; Pinfold, T. L.; Lennard, P. R.; Woods, G. M.; Lyons, A. B.; Flies, A. S.
10.1101/2020.06.11.145789 — immunology — Posted on 2020-06-12
2998 High Content Screening and Proteomic Analysis Identify the Kinase Inhibitor BX795 as a Potent Neuroprotective Compound in a Patient-Derived Model of Parkinson's Disease
Antoniou, N.; Prodromidou, K.; Kouroupi, G.; Samiotaki, M.; Panayotou, G.; Xilouri, M.; Stefanis, L.; Grailhe, R.; Taoufik, E.; Matsas, R.
10.1101/2020.06.12.148031 — neuroscience — Posted on 2020-06-12
3003 Association of poor virus specific immunoglobulin G antibodyresponses with higher viral load is seen in Bangladeshi pregnantwomen having acute Hepatitis E Genotype 1 infection
Sultana, R.; Islam, M. T.; Bhuyan, G. S.; Noor, F. A.; Sarker, S. K.; Maliha, N.; Hassan, Z.; Hossain, M.; Rashid, M.; Zaman, K.; Karim, M. M.; Qadri, F.; Mannoor, K.
10.1101/2020.06.12.148528 — immunology — Posted on 2020-06-12
3009 Enteropathogenic Escherichia coli (EPEC) Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations and Increased Intestinal Permeability in a Murine Model
Ledwaba, E.; Costa, D.; Bolick, D. T.; Giallourou, N.; Medeiros, P. H. Q. S.; Swann, J.; Traore-Hoffman, A.; Potgieter, N.; Nataro, J.; Guerrant, R. L.
10.1101/2020.06.12.148593 — microbiology — Posted on 2020-06-12
3020 Prelimbic-amygdala overexcitability mediates trait vulnerability in a novel mouse model of acute social defeat stress
Grossman, Y. S.; Fillinger, C.; Manganaro, A.; Voren, G.; Waldman, R.; Zou, T.; Jannsen, W.; Kenny, P.; Dumitriu, D.
10.1101/2020.06.11.147231 — neuroscience — Posted on 2020-06-12
3021 Molecular diversity of glutamatergic and GABAergic synapses from multiplexed fluorescence imaging
Danielson, E. W.; Perez de Arce, K.; Cimini, B.; Wamhoff, E.-C.; Singh, S.; Cottrell, J. R.; Carpenter, A. E.; Bathe, M.
10.1101/2020.06.12.148155 — neuroscience — Posted on 2020-06-12
3022 Computational approaches identify novel transcription factor combinations that promote corticospinal axon growth following injury
Venkatesh, I.; Mehra, V.; Wang, Z.; Simpson, M. T.; Eastwood, E.; Chakraborty, A.; Beine, Z.; Gross, D.; Cabahug, M.; Olson, G.; Blackmore, M. G.
10.1101/2020.06.12.146159 — neuroscience — Posted on 2020-06-12
3023 Disentangling interactions between mercury, immunity, and infection in a Neotropical bat community
Becker, D.; Speer, K.; Korstian, J.; Volokhov, D.; Droke, H.; Brown, A.; Baijnauth, C.; Padgett-Stewart, T.; Broders, H.; Plowright, R.; Rainwater, T.; Fenton, M. B.; Simmons, N.; Chumchal, M.
10.1101/2020.06.12.135475 — ecology — Posted on 2020-06-12
3025 An Integrative Genetic, Epigenetic and Proteomic Characterization of Pancreatic Neuroendocrine Neoplasms (PanNENs) defines Distinct Molecular Features of α- and β-cell like Subgroups
Simon, T.; Mamlouk, S.; Riemer, P.; Bormann, F.; Klinger, B.; Menne, A.; Teichmann, D.; Wanke-Moehr, K.; Pacyna-Gengelbach, M.; Khouja, S.; Lenze, D.; Capper, D.; Ruoff, F.; Templin, M.; Leser, U.; Detjen, K.; Rossner, F.; Haybaeck, J.; Morkel, M.; Bluethgen, N.; Horst, D.; Pavel, M.; Sers, C.
10.1101/2020.06.12.146811 — cancer biology — Posted on 2020-06-12
3026 SCIM: Universal Single-Cell Matching with Unpaired Feature Sets
Stark, S. G.; Ficek, J.; Lehmann, K.; Bonilla, X.; Locatello, F.; Rätsch, G.; Chevrier, S.; Singer, F.
10.1101/2020.06.11.146845 — bioinformatics — Posted on 2020-06-12
3027 Inhibiting proBDNF to mature BDNF conversion leads to autism-like phenotypes in vivo
You, H.; Mizui, T.; Kiyosue, K.; Takao, K.; Miyakawa, T.; Kato, K.; Otsuka, M.; Bai, T.; Xia, K.; Lu, B.; Kojima, M.
10.1101/2020.06.12.149104 — neuroscience — Posted on 2020-06-12
3030 Cortical dynamics underlying social behavior in dominance hierarchy and spatial navigation
Lara-Vasquez, A.; Espinosa, N.; Morales, C.; Moran, C.; Billeke, P.; Gallagher, J.; Strohl, J.; Huerta, P. T.; Fuentealba, P.
10.1101/2020.06.12.147249 — neuroscience — Posted on 2020-06-12
3034 Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients
Kreer, C.; Zehner, M.; Weber, T.; Rohde, C.; Halwe, S.; Ercanoglu, M. S.; Gieselmann, L.; Korenkov, M.; Gruell, H.; Schommers, P.; Vanshylla, K.; Di Cristanziano, V.; Janicki, H.; Brinker, R.; Ashurov, A.; Kraehling, V.; Kupke, A.; Cohen-Dvashi, H.; Koch, M.; Lederer, S.; Pfeifer, N.; Wolf, T.; Vehreschild, M. J. G. T.; Wendtner, C.; Diskin, R.; Becker, S.; Klein, F.
10.1101/2020.06.12.146290 — immunology — Posted on 2020-06-12
3035 A pan-genome method to determine core regions of the Bacillus subtilis and Escherichia coli genomes
Sutton, G. G.; Fogel, G. B.; Abramson, B.; Brinkac, L. M.; Michael, T. P.; Liu, E. S.; Thomas, S.
10.1101/2020.06.11.147629 — evolutionary biology — Posted on 2020-06-12
3038 Exosite inhibition of A Disintegrin And Metalloproteinase with Thrombospondin motif (ADAMTS)-5 by a glycoconjugated arylsulfonamide
Santamaria, S.; Cuffaro, D.; Nuti, E.; Ciccone, L.; Tuccinardi, T.; Liva, F.; D'Andrea, F.; de Groot, R.; Rossello, A.; Ahnstroem, J.
10.1101/2020.06.12.146324 — biochemistry — Posted on 2020-06-12
3039 Substrate-dependent suppression of oxidative phosphorylation in the Frataxin-depleted heart
Vasquez, C.; Patel, M.; Sivaramakrishnan, A.; Bekeova, C.; Anderson-Pullinger, L.; Wang, N.; Seifert, E. L.
10.1101/2020.06.12.148361 — biochemistry — Posted on 2020-06-12
3042 Persistence of quantal synaptic vesicle recycling following dynamin depletion
Kavalali, E. T.; Afuwape, O.; Chanaday, N.; Kasap, M.; Monteggia, L. M.
10.1101/2020.06.12.147975 — neuroscience — Posted on 2020-06-12
3043 Bilateral but not unilateral subthalamic stimulation promotes apathy: a translational study in rodents and Parkinson's disease patients
Vachez, Y.; Bahout, M.; Magnard, R.; David, P.-M.; Carcenac, C.; Robert, G.; Savasta, M.; Carnicella, S.; Vérin, M.; Boulet, S.
10.1101/2020.06.11.147116 — neuroscience — Posted on 2020-06-12
3046 The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity
Zhang, L.; Jackson, C. B.; Mou, H.; Ojha, A.; Rangarajan, E. S.; Izard, T.; Farzan, M.; Choe, H.
10.1101/2020.06.12.148726 — microbiology — Posted on 2020-06-12
3048 A peptide-signal amplification strategy for the detection and validation of neoepitope presentation on cancer biopsies
Ramarathinam, S. H.; Faridi, P.; Peng, A.; Szeto, P.; Wong, N. C.; Behren, A.; Shackleton, M.; Purcell, A. W.
10.1101/2020.06.12.145276 — immunology — Posted on 2020-06-12
3049 MHC class I and II genes in Serpentes
Olivieri, D. N.; Mirete-Bachiller, S.; Gambon-Deza, F.
10.1101/2020.06.12.133363 — immunology — Posted on 2020-06-12
3054 Genome evolution and pathoadaptation of Shigella
Seferbekova, Z.; Zabelkin, A.; Yakovleva, Y.; Afasizhev, R.; Alexeev, N.; Gelfand, M. S.; Bochkareva, O. O.
10.1101/2020.06.12.147751 — bioinformatics — Posted on 2020-06-12
3057 Transdiagnostic dimensions of psychopathology explain individuals' unique deviations from normative neurodevelopment in brain structure
Parkes, L.; Moore, T. M.; Calkins, M. E.; Cook, P. A.; Cieslack, M.; Roalf, D. R.; Wolf, D. H.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2020.06.11.147009 — neuroscience — Posted on 2020-06-12
3058 Enhanced analgesic cholinergic tone after neuropathy
Dhanasobhon, D.; Medrano, M.-C.; Moreno-Lopez, Y.; Kavraal, S.; Bichara, C.; Schlichter, R.; Inquimbert, P.; Yalcin, I.; Cordero-Erausquin, M.
10.1101/2020.06.11.146852 — neuroscience — Posted on 2020-06-12
3060 Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
Hurlburt, N. K.; Wan, Y.-H.; Stuart, A. B.; Feng, J.; McGuire, A. T.; Stamatatos, L.; Pancera, M.
10.1101/2020.06.12.148692 — immunology — Posted on 2020-06-12
3061 Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early prognostic marker for severe COVID-19
Carissimo, G.; Xu, W.; Kwok, I.; Abdad, M. Y.; Chan, Y. H.; Fong, S. W.; Puan, K. J.; Lee, C. Y. P.; Yeo, N. K.-W.; Amrun, S. N.; Chee, R. S.-L.; How, W.; Chan, S.; Fan, E. B.; Andiappan, A.; Lee, B.; Rotzschke, O.; Young, B. E.; Leo, Y.-S.; Lye, D. C.; Renia, L.; Ng, L. G.; Larbi, A.; Ng, L. F.
10.1101/2020.06.11.147389 — immunology — Posted on 2020-06-12
3066 Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate
Iserman, C.; Roden, C. A.; Boerneke, M.; Sealfon, R.; McLaughlin, G.; Jungreis, I.; Park, C. Y.; Boppana, A.; Fritch, E.; Hou, Y.; Theesfeld, C.; Troyanskaya, O.; Baric, R. S. G.; Sheahan, T. P.; Weeks, K.; Gladfelter, A.
10.1101/2020.06.11.147199 — biochemistry — Posted on 2020-06-12
3070 Machine Learning Maps Research Needs in COVID-19 Literature
Doanvo, A. L.; Qian, X.; Ramjee, D.; Piontkivska, H.; Desai, A. N.; Majumder, M. S.
10.1101/2020.06.11.145425 — scientific communication and education — Posted on 2020-06-12
3075 Neural signatures of pathological hyperdirect pathway activity in Parkinson's disease
Oswal, A.; Yeh, C.-H.; Neumann, W.-J.; Gratwicke, J.; Akram, H.; Horn, A.; Zrinzo, L.; Foltynie, T.; Limousin, P.; Bogacz, R.; Husain, M.; Brown, P.; Litvak, V.
10.1101/2020.06.11.146886 — neuroscience — Posted on 2020-06-12
3078 The genetic organization of subcortical volumetric change is stable throughout the lifespan
Fjell, A.; Grydeland, H.; Wang, Y.; Amlien, I. K.; Bartres-Faz, D.; Brandmaier, A.; Duzel, S.; Elman, J.; Franz, C.; Haberg, A.; Kietzmann, T. C.; Kievit, R. A.; Kremen, W.; Krogsrud, S. K.; Kuhn, S. A.; Lindenberger, U.; Macia, D.; Mowinckel, A. M.; Nyberg, L.; Panizzon, M.; Sole-Padulles, C.; Sorensen, O.; Westerhausen, R.; Walhovd, K. B.
10.1101/2020.06.12.143834 — neuroscience — Posted on 2020-06-12
3081 Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens
de Waard, A. A.; Verkerk, T.; Hoefakker, K.; van der Steen, D. M.; Jongsma, M. L. M.; Bliss, S.; de Ru, A. H.; van Veelen, P. A.; Griffioen, M.; Heemskerk, M. H. M.; Spaapen, R. M.
10.1101/2020.06.11.146449 — immunology — Posted on 2020-06-12
3082 A Versatile Platform to Incorporate Viral Trimeric Antigens into Self-Assembling Nanoparticle Immunogens
Zhang, B.; Chao, C. W.; Tsybovsky, Y.; Olia, A. S.; Stewart-Jones, G.; Verardi, R.; Wang, S.; Zhou, T.; Kwong, P. D.
10.1101/2020.06.11.147496 — immunology — Posted on 2020-06-12
3084 Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1
Brownstein, Z.; Gulsuner, S.; Walsh, T.; Martins, F. T. A.; Taiber, S.; Isakov, O.; Lee, M.; Bordeynik-Cohen, M.; Birkan, M.; Chang, W.; Casadei, S.; Danial-Farran, N.; Abu Rayyan, A.; Carlson, R.; Kamal, L.; Arnporsson, A. O.; Sokolov, M.; Gilony, D.; Lipschitz, N.; Frydman, M.; Davidov, B.; Macarov, M.; Sagi, M.; Vinkler, C.; Poran, H.; Sharony, R.; Samara, N.; Zvi, N.; Baris-Feldman, H.; Singer, A.; Handzel, O.; Hertzano, R.; Ali-Naffaa, D.; Ruhrman-Shahar, N.; Madgar, O.; Sofrin, E.; Peleg, A.; Khayat, M.; Shohat, M.; Basel-Salmon, L.; Pras, E.; Lev, D.; Wolf, M.; Steingrimsson, E.; Shomro
10.1101/2020.06.11.144790 — genetics — Posted on 2020-06-12
3088 Multiple binding sites for resin-acid derivatives on the voltage-sensor domain of the Shaker potassium channel
Silvera Ejneby, M.; Gromova, A.; Ottosson, N. E.; Borg, S.; Estrada-Mondragon, A.; Yazdi, S.; Apostolakis, P.; Elinder, F.; Delemotte, L.
10.1101/2020.06.11.146548 — biophysics — Posted on 2020-06-12
3090 Bridging scales in scattering tissues via multifocal two-photon microscopy
Chen, D.; Segovia-Miranda, F.; Walker, N.; Valenzuela, J. I.; Zerial, M.; Myers, E. W.
10.1101/2020.06.11.146704 — bioengineering — Posted on 2020-06-12
3091 Direct RNA sequencing reveals structural differences between transcript isoforms
Aw, A. J. G.; Lim, S.; Wang, J. X.; Shen, Y.; Kaewsapsak, P.; Kok, E. P. L.; Li, C.; Ng, B. H.; Vardy, L. A.; Tan, M. H.; Nagarajan, N.; Wan, Y.
10.1101/2020.06.11.147223 — biochemistry — Posted on 2020-06-12
3093 Simple Assay, Kinetics, and Biochemical Trends for Soil Microbial Catalases
Chabot, M.; Morales, E.; Cummings, J.; Rios, N.; Giatpaiboon, S. A.; Mogul, R.
10.1101/2020.06.11.147595 — biochemistry — Posted on 2020-06-12
3094 Neuroscience Cloud Analysis As a Service
Abe, T.; Kinsella, I.; Saxena, S.; Paninski, L.; Cunningham, J. P.
10.1101/2020.06.11.146746 — neuroscience — Posted on 2020-06-12
3095 Both HIV Infection and Conditional Tat Expression Decrease Prepulse Inhibition with Further Impairment by Methamphetamine History in Humans
Walter, T.; Young, J.; Milienne-Petiot, M.; Deben, D. S.; Heaton, R.; Letendre, S.; Grelotti, D.; Perry, W.; Grant, I.; Minassian, A.
10.1101/2020.06.11.130666 — neuroscience — Posted on 2020-06-12
3096 Extracellular histones trigger disseminated intravascular coagulation by lytic cell death
Wu, C.; Zhang, Y.; Li, L.; Pandeya, A.; Zhang, G.; Cui, J.; Kirchhofer, D.; Wood, J. P.; Smyth, S. S.; Wei, Y.; Li, Z.
10.1101/2020.06.11.144683 — immunology — Posted on 2020-06-12
3097 Highly sensitive and specific multiplex antibody assays to quantify immunoglobulins M, A and G against SARS-CoV-2 antigens
Dobano, C.; Vidal, M.; Santano, R.; Jimenez, A.; Chi, J.; Barrios, D.; Ruiz-Olalla, G.; Rodrigo Melero, N.; Carolis, C.; Parras, D.; Serra, P.; Martinez de Aguirre, P.; Carmona-Torre, F.; Reina, G.; Santamaria, P.; Mayor, A.; Alberto Garcia-Basteiro, A.; Izquierdo, L.; Aguilar, R.; Moncunill, G.
10.1101/2020.06.11.147363 — immunology — Posted on 2020-06-12
3098 Enhanced C/EBPs binding to C>T mismatches facilitates fixation of CpG mutations
Ershova, A. S.; Eliseeva, I. A.; Nikonov, O. S.; Fedorova, A. D.; Vorontsov, I. E.; Papatsenko, D.; Kulakovskiy, I. V.
10.1101/2020.06.11.146175 — genomics — Posted on 2020-06-12
3099 Gene expression variability in human and chimpanzee populations share common determinants
Fair, B. J.; Blake, L. E.; Sarkar, A.; Pavlovic, B. J.; Cuevas, C.; Gilad, Y.
10.1101/2020.06.11.146142 — genomics — Posted on 2020-06-12
3104 Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs
Zhang, M.; Gui, M.; Wang, Z.-F.; Gorgulla, C.; Yu, J.; Wu, H.; Sun, Z.-Y. J.; Klenk, C.; Merkinger, L.; Morstein, L.; Hagn, F.; Plueckthun, A.; Brown, A.; Nasr, M. L.; Wagner, G.
10.1101/2020.06.11.145912 — molecular biology — Posted on 2020-06-12
3105 Hidden in plain sight: The effects of BCG vaccination in COVID-19 pandemic
Toriah, E. A.; Sedhom, J. A.; Dokunmu, T. M.; Hussein, M. H.; Ruiz, E. M.; Muthusamy, K.; Zerfaoui, M.; Kandil, E.
10.1101/2020.06.09.142760 — immunology — Posted on 2020-06-12
3106 LRRC8A regulates hypotonicity-induced NLRP3 inflammasome activation
Green, J. P.; Swanton, T.; Morris, L. V.; El-Sharkawy, L. Y.; Cook, J.; Yu, S.; Beswick, J.; Adamson, A. D.; Humphreys, N. E.; Bryce, R.; Freeman, S.; Lawrence, C.; Brough, D.
10.1101/2020.06.11.146225 — immunology — Posted on 2020-06-12
3113 Light-dependent translation change of Arabidopsis psbA correlates with RNA structure alterations at the translation initiation region
Gawronski, P.; Enroth, C.; Kindgren, P.; Marquardt, S.; Karpinski, S.; Leister, D.; Jensen, P. E.; Vinther, J.; Scharff, L. B.
10.1101/2020.06.11.145870 — plant biology — Posted on 2020-06-12
3115 Temporal dynamics of QTL effects on vegetative growth in Arabidopsis thaliana
Meyer, R. C.; Weigelt-Fischer, K.; Knoch, D.; Heuermann, M. C.; Zhao, Y.; Altmann, T.
10.1101/2020.06.11.145953 — plant biology — Posted on 2020-06-12
3118 Tabula-rasa exploration decreases during youth and is linked to ADHD symptoms
Dubois, M.; Aislinn, B.; Moses-Payne, M. E.; Habicht, J.; Steinbeis, N.; Hauser, T. U.
10.1101/2020.06.11.146019 — neuroscience — Posted on 2020-06-12
3120 The Ancient DNA Insights into Aboriginal Australian Mortuary Practices
Wasef, S.; Wright, J. L.; Adams, S.; Westaway, M. C.; Flinders, C.; Willerslev, E.; Lambert, D. M.
10.1101/2020.06.11.145482 — evolutionary biology — Posted on 2020-06-12
3121 In situ structure of the AcrAB-TolC efflux pump at subnanometer resolution
Wang, Z.; Chen, M.; Shi, X.; Yu, Z.; Fan, G.; Serysheva, I. I.; Baker, M.; Luisi, B.; Ludtke, S.
10.1101/2020.06.10.144618 — biophysics — Posted on 2020-06-12
3125 Rapid ageing and species identification of natural mosquitoes for malaria surveillance
Siria, D. J.; Sanou, R.; Mitton, J.; Mwanga, E.; Niang, A.; Sare, I.; Johnson, P. C. D.; Foster, G.; Belem, A.; Wynne, K.; Murray-Smith, R.; Ferguson, H. M.; Gonzalez Jimenez, M.; Babayan, S.; Diabate, A.; Okumu, F. O.; Baldini, F.
10.1101/2020.06.11.144253 — zoology — Posted on 2020-06-12
3126 Phytohormone production by the arbuscular mycorrhizal fungus Rhizophagus irregularis
Pons, S.; Fournier, S.; Chervin, C.; Becard, G.; Rochange, S.; Frei-dit-frey, N.; Puech-pages, V.
10.1101/2020.06.11.146126 — plant biology — Posted on 2020-06-12
3127 Genome-Wide High Resolution Expression Map and Functions of Key Cell Fate Determinants Reveal the Dynamics of Crown Root Development in Rice
Garg, T.; Singh, Z.; Dwivedi, A. K.; Varapparambathu, V.; Singh, R. S.; Yadav, M.; Chandran, D.; Prasad, K.; Jain, M.; Yadav, S. R.
10.1101/2020.06.11.131565 — plant biology — Posted on 2020-06-12
3128 An ABA Synthesis Enzyme Allele OsNCED2 Promotes the Aerobic Adaption in Upland Rice
Hu, F.; Huang, L.; Bao, Y.; Qin, S.; Ning, M.; Lyu, J.; Zhang, S.; Huang, G.; Zhang, J.; Wang, W.; Fu, B.
10.1101/2020.06.11.146092 — plant biology — Posted on 2020-06-12
3130 Parabrachial neuron types categorically encode thermoregulation variables during heat defense
Yang, W. Z.; Du, X.; Zhang, W.; Gao, C.; Xie, H.; Xiao, Y.; Jia, X.; Liu, J.; Xu, J.; Fu, X.; Tu, H.; Fu, X.; Ni, X.; He, M.; Yang, J.; Wang, H.; Yang, H.; Xu, X.-H.; Shen, W.
10.1101/2020.06.11.138370 — neuroscience — Posted on 2020-06-12
3133 A two-locus system with strong epistasis underlies rapid parasite-mediated evolution of host resistance
Ameline, C.; Bourgeois, Y. X. C.; Voegtli, F.; Savola, E.; Andras, J.; Engelstaedter, J.; Ebert, D.
10.1101/2020.06.11.145391 — evolutionary biology — Posted on 2020-06-12
3135 Factors influencing riverine utilization patterns in two sympatric macaques
Otani, Y.; Bernard, H.; Wong, A.; Tangah, J.; Tuuga, A.; Hanya, G.; Matsuda, I.
10.1101/2020.06.11.145409 — ecology — Posted on 2020-06-12
3137 Over-accessible chromatin links myeloma initiating genetic events to oncogenic transcriptomes and aberrant transcription factor regulatory networks
Alvarez-Benayas, J.; Katsarou, A.; Trasanidis, N.; Chaidos, A.; May, P. C.; Ponnusamy, K.; Xiao, X.; Bua, M.; Atta, M.; Roberts, I. A.; Auner, H. W.; Hatjiharissi, E.; Papaioannou, M.; Caputo, V. S.; Sudbery, I. M.; Karadimitris, A.
10.1101/2020.06.11.140855 — cancer biology — Posted on 2020-06-12
3139 SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals
Lam, S. D.; Bordin, N.; Waman, V. P.; Scholes, H. M.; Ashford, P.; Sen, N.; van Dorp, L.; Rauer, C.; Dawson, N. L.; Pang, C. S.; Abbasian, M.; Sillitoe, I.; Edwards, S. J.; Fraternali, F.; Lees, J. G.; Santini, J. M.; Orengo, C. A.
10.1101/2020.05.01.072371 — bioinformatics — Posted on 2020-06-12
3141 Reproducible, portable, and effcient ancient genome reconstruction with nf-core/eager
Fellows Yates, J. A.; Lamnidis, T. C.; Borry, M.; Andrades Valtuena, A.; Fagneräs, Z.; Clayton, S.; Garcia, M. U.; Neukamm, J.; Peltzer, A.
10.1101/2020.06.11.145615 — bioinformatics — Posted on 2020-06-12
3143 The impact of super-spreaders in COVID-19: mapping genome variation worldwide
Gomez-Carballa, A.; Bello, X.; Pardo-Seco, J.; Martinon-Torres, F.; Salas, A.
10.1101/2020.05.19.097410 — genomics — Posted on 2020-06-12
3146 Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity
Mellis, I. A.; Edelstein, H. I.; Truitt, R.; Beck, L. E.; Symmons, O.; Goyal, Y.; Dunagin, M. C.; Linares Saldana, R. A.; Shah, P. P.; Yang, W.; Jain, R.; Raj, A.
10.1101/2020.06.11.147207 — systems biology — Posted on 2020-06-12
3148 Prediction of complex phenotypes using the Drosophila metabolome
Rohde, P. D.; Kristensen, T. N.; Sarup, P.; Munoz, J.; Malmendal, A.
10.1101/2020.06.11.145623 — genetics — Posted on 2020-06-12
3151 The genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides
Fisher, M. F.; Payne, C.; Chetty, T.; Crayn, D.; Berkowitz, O.; Whelan, J.; Rosengren, K. J.; Mylne, J. S.
10.1101/2020.06.10.145326 — biochemistry — Posted on 2020-06-12
3152 Opponent intracerebral signals for reward and punishment prediction errors in humans
Gueguen, M. C.; Billeke, P.; Lachaux, J.-P.; Rheims, S.; Kahane, P.; Minotti, L.; David, O.; pessiglione, m.; Bastin, J.
10.1101/2020.06.11.145433 — neuroscience — Posted on 2020-06-12
3153 Identification of a lymphocyte minor histocompatibility antigen in Mauritian cynomolgus macaques
Weinfurter, J. T.; Graham, M. E.; Ericsen, A. J.; Matschke, L. M.; Llewellyn-Lacey, S.; Price, D. A.; Wiseman, R. W.; Reynolds, M. R.
10.1101/2020.06.10.145250 — immunology — Posted on 2020-06-12
3154 Cohesin residency determines chromatin loop patterns
costantino, l.; Hsieh, T.-H. S.; Lamothe, R.; Darzacq, X. D.; Koshland, D. E.
10.1101/2020.06.11.146902 — genomics — Posted on 2020-06-12
3158 Improving Landsat predictions of rangeland fractional cover with multitask learning and uncertainty
Allred, B. W.; Bestelmeyer, B. T.; Boyd, C. S.; Brown, C.; Davies, K. W.; Ellsworth, L. M.; Erickson, T. A.; Fuhlendorf, S. D.; Griffiths, T. V.; Jansen, V.; Jones, M. O.; Karl, J.; Maestas, J. D.; Maynard, J. J.; McCord, S. E.; Naugle, D. E.; Starns, H. D.; Twidwell, D.; Uden, D. R.
10.1101/2020.06.10.142489 — ecology — Posted on 2020-06-12
3162 Integrated gut-liver-on-a-chip platform as an in vitro human model of non-alcoholic fatty liver disease
Yang, J.; Hirai, Y.; Iida, K.; Trumm, M.; Terada, S.; Sakai, R.; Tsuchiya, T.; Tabata, O.; Kamei, K.-i.
10.1101/2020.06.10.141606 — bioengineering — Posted on 2020-06-12
3163 Inhibition underlies fast undulatory locomotion in C. elegans
Deng, L.; Denham, J.; Arya, C.; Yuval, O.; Cohen, N.; Haspel, G.
10.1101/2020.06.10.138578 — neuroscience — Posted on 2020-06-12
3164 Evolutionary heritage shapes tree distributions along an Amazon-to-Andes elevation gradient
Griffiths, A. R.; Silman, M. R.; Farfan Rios, W.; Feeley, K. J.; Garcia Cabrera, K.; Meir, P.; Salinas, N.; Dexter, K. G.
10.1101/2020.06.11.143875 — ecology — Posted on 2020-06-12
3165 Opto-E-Dura: a Soft, Stretchable ECoG Array for Multimodal, Multi-scale Neuroscience
Renz, A.; Lee, J.; Tybrandt, K.; Brzezinski, M.; Mercado, D.; Cerra Cheraka, M.; Lee, J.; Helmchen, F.; Voros, J.; Lewis, C. M.
10.1101/2020.06.10.139493 — neuroscience — Posted on 2020-06-12
3167 Beyond forest succession: a gap model to study ecosystem functioning and tree community composition under climate change
Morin, X.; de Coligny, F.; Martin-StPaul, N.; Bugmann, H.; Cailleret, M.; Limousin, J.-M.; Ourcival, J.-M.; Prevosto, B.; Simioni, G.; Vennetier, M.; Guillemot, J.
10.1101/2020.06.10.140616 — ecology — Posted on 2020-06-12
3174 Emotional Metacognition: Stimulus Valence Modulates Cardiac Arousal and Metamemory
Legrand, N.; Engen, S. S.; Correa, C.; Mathiasen, N. K.; Nikolova, N.; Fardo, F.; Allen, M.
10.1101/2020.06.10.144428 — neuroscience — Posted on 2020-06-12
3177 Predicting future cognitive decline from non-brain and multimodal brain imaging data in healthy and pathological aging
Liem, F.; Dadi, K.; Engemann, D. A.; Gramfort, A.; Bellec, P.; Craddock, R. C.; Damoiseaux, J. S.; Steele, C. J.; Yarkoni, T.; Margulies, D. S.; Varoquaux, G.
10.1101/2020.06.10.142174 — neuroscience — Posted on 2020-06-12
3179 Does rainforest biodiversity stand on the shoulders of giants? Effect of disturbances by forest elephants on trees and insects on Mount Cameroon
Maicher, V.; Delabye, S.; Murkwe, M.; Dolezal, J.; Altman, J.; Kobe, I. N.; Desmist, J.; Fokam, E. B.; Pyrcz, T.; Tropek, R.
10.1101/2020.06.10.144279 — ecology — Posted on 2020-06-12
3181 Mechanistic insights into volatile anesthetic modulation of K2P channels
Wague, A.; Joseph, T. T.; Woll, K. A.; Bu, W.; Vaidya, K. A.; Bhanu, N. V.; Garcia, B. A.; Nimigean, C. M.; Eckenhoff, R. G.; Riegelhaupt, P. M.
10.1101/2020.06.10.144287 — pharmacology and toxicology — Posted on 2020-06-12
3183 PD-L1hi plasmablasts limit the T cell response during the acute phase of parasite infections
Gorosito Serran, M.; Fiocca Vernengo, F.; Almada, L.; Beccaria, C. G.; Canete, P. F.; Rocco Alegre, J.; Tosello Boari, J.; Ramello, M. C.; Wehrens, E.; Cai, Y.; Zuniga, E. I.; Montes, C. L.; Acosta Rodriguez, E. V.; Cockburn, I. A.; Vinuesa, C. G.; Gruppi, A.
10.1101/2020.06.10.142067 — immunology — Posted on 2020-06-12
3184 Assessing the reliability of species distribution projections in climate change research
Santini, L.; Benitez-Lopez, A.; Cengic, M.; Maiorano, L.; Huijbregts, M. A. J.
10.1101/2020.06.10.143917 — ecology — Posted on 2020-06-12
3185 Mutational inactivation of Apc in the intestinal epithelia compromises cellular organisation
Rannikmae, H.; Peel, S.; Barry, S.; Sur, I. K.; Taipale, J.; Senda, T.; de la Roche, M.
10.1101/2020.06.10.143800 — cell biology — Posted on 2020-06-12
3187 Direct structural connections between auditory and visual motion selective regions in humans
Gurtubay-Antolin, A.; Battal, C.; Maffei, C.; Rezk, M.; Mattioni, S.; Jovicich, J.; Collignon, O.
10.1101/2020.06.11.145490 — neuroscience — Posted on 2020-06-12
3188 REALM: AO-based localization microscopy deep in complex tissue
Siemons, M. E.; Hanemaaijer, N. A. K.; Kole, M. H. P.; Kapitein, L. C.
10.1101/2020.06.12.147884 — cell biology — Posted on 2020-06-12
3189 An integrative study of five biological clocks in somatic and mental health
Jansen, R.; Verhoeven, J.; Han, L. K.; Aberg, K. A.; van den Oord, E.; Milaneschi, Y.; Penninx, B. W.
10.1101/2020.06.11.146498 — cell biology — Posted on 2020-06-12
3193 Time meets space: brain dynamics drive spatial topography
Golesorkhi, M.; Tumati, S.; Gomez-Pilar, J.; Stamatakis, E.; Northoff, G.
10.1101/2020.06.11.106476 — neuroscience — Posted on 2020-06-12
3194 NMDAR-mediated transcriptional control of geneexpression in the specification of interneuron subtype identity
Mahadevan, V.; Mitra, A.; Zhang, Y.; Peltekian, A.; Chittajallu, R.; Esnault, C.; Maric, D.; Rhodes, C.; Pelkey, K. A.; Dale, R. K.; Petros, T. J.; McBain, C. J.
10.1101/2020.06.10.144295 — neuroscience — Posted on 2020-06-12
3196 Discovery of cryptic plant diversity in one of the harshest environments: the rooftops of the Alps
Boucher, F. C.; Dentant, C.; Ibanez, S.; Capblancq, T.; Boleda, M.; Boulangeat, L.; Smycka, J.; Roquet, C.; Camille Nous, C.; Lavergne, S.
10.1101/2020.06.10.144105 — evolutionary biology — Posted on 2020-06-12
3197 The conserved molting/circadian rhythm regulator NHR-23/NR1F1 serves as an essential co-regulator of C. elegans spermatogenesis
Ragle, J. M.; Aita, A. L.; Morrison, K. N.; Martinez-Mendez, R.; Saeger, H. N.; Ashley, G. A.; Johnson, L. C.; Schubert, K. A.; Shakes, D. C.; Ward, J. D.
10.1101/2020.06.11.147298 — developmental biology — Posted on 2020-06-12
3200 Neuro-computational mechanisms of action-outcome learning under moral conflict
Nostro, A.; Ioumpa, K.; Paracampo, R.; Gallo, S.; Fornari, L.; De Angelis, L.; Gentile, A.; Spezio, M.; Keysers, C.; Gazzola, V.
10.1101/2020.06.10.143891 — neuroscience — Posted on 2020-06-12
3202 Neuroinflammation in the normal appearing white matter of multiple sclerosis brain causes abnormalities at the node of Ranvier
Gallego, P.; James, R.; Browne, E.; Meng, J.; Umashankar, S.; Picon, C.; Mazarakis, N. D.; Faisal, A.; Howell, O. W.; Reynolds, R.
10.1101/2020.06.10.142281 — neuroscience — Posted on 2020-06-12
3203 Intraspecific diversity loss in a predator species alters prey community structure and ecosystem functions
Raffard, A.; Cucherousset, J.; Montoya, J. M.; Richard, M.; Acoca-Pidolle, S.; Poesy, C.; Garreau, A.; Santoul, F.; Blanchet, S.
10.1101/2020.06.10.144337 — ecology — Posted on 2020-06-12
3207 CD38 dependent NAD+ depletion contributes to oligodendrocyte loss and inhibition of myelin regeneration
Langley, M. R.; Choi, C.-I.; Peclat, T. R.; Kleppe, L.; Simon, W. L.; Yoon, H.; Chini, C. C.; Chini, E. N.; Scarisbrick, I. A.
10.1101/2020.06.10.143941 — neuroscience — Posted on 2020-06-12
3208 A Genome-based Model to Predict the Virulence of Pseudomonas aeruginosa Isolates
Pincus, N. B.; Ozer, E. A.; Allen, J.; Nguyen, M.; Davis, J. J.; Winter, D. R.; Chuang, C.-H.; Chiu, C.-H.; Zamorano, L.; Oliver, A.; Hauser, A. R.
10.1101/2020.06.09.143610 — genomics — Posted on 2020-06-12
3209 High resilience of the mycorrhizal community to prescribed seasonal burnings in a Mediterranean woodland
Livne- Luzon, S.; Shemesh, H.; Osem, Y.; Carmel, Y.; Migael, H.; Avidan, Y.; Tsafrir, A.; Glassman, S. I.; Bruns, T. D.; Ovadia, O.
10.1101/2020.06.10.141671 — ecology — Posted on 2020-06-12
3210 MDM2 Inhibition in Combination with Endocrine Therapy and CDK4/6 Inhibition for the Treatment of ER-Positive Breast Cancer.
Portman, N.; Milioli, H. H.; Alexandrou, S.; Coulson, R.; Yong, A.; Fernandez, K. J.; Chia, K.; Segara, D.; Parker, A.; Haupt, S.; Haupt, Y.; Tilley, W. D.; Swarbrick, A.; Caldon, C. E.; Lim, E.
10.1101/2020.06.09.140921 — cancer biology — Posted on 2020-06-12
3211 GSTU7 affects growth performance and acts as an antagonist of oxidative stress induced by methyl viologen
Ugalde, J. M.; Lamig, L.; Herrera-Vasquez, A.; Fuchs, P.; Müller-Schüssele, S. J.; Meyer, A. J.; Holuigue, L.
10.1101/2020.06.09.142729 — plant biology — Posted on 2020-06-12
3212 Reovirus σ1 conformational flexibility modulates the efficiency of host cell attachment
Diller, J. R.; Halloran, S. R.; Koehler, M.; dos Santos Natividade, R.; Alsteens, D.; Stehle, T.; Dermody, T. S.; Ogden, K. M.
10.1101/2020.06.09.143594 — microbiology — Posted on 2020-06-12
3213 Ctenophore immune cells produce chromatin traps in response to pathogens and NADPH-independent stimulus
Vandepas, L. E.; Stefani, C.; Traylor-Knowles, N.; Goetz, F. W.; Browne, W. E.; Lacy-Hulbert, A.
10.1101/2020.06.09.141010 — evolutionary biology — Posted on 2020-06-12
3216 Cytolethal Distending Toxin: from mitotic DNA damage to cGAS-dependent pro-inflammatory response
Pons, B. J.; Pettes-Duler, A.; Naylies, C.; Taieb, F.; Hashim, S.; Tadrist, S.; Lippi, Y.; Mirey, G.; Vignard, J.
10.1101/2020.06.09.141648 — cell biology — Posted on 2020-06-12
3217 Transcriptional profiling reveals T cells cluster around neurons injected with Toxoplasma gondii proteins
Merritt, E. F.; Johnson, H. J.; Wong, Z. S.; Buntzman, A. S.; Conklin, A. C.; Cabral, C. M.; Romanoski, C. E.; Boyle, J. P.; Koshy, A. A.
10.1101/2020.06.09.143099 — bioinformatics — Posted on 2020-06-12
3218 Requirement for proper mitochondrial RNA processing in the restrictive control of cell proliferation during early lateral root morphogenesis
Otsuka, K.; Mamiya, A.; Konishi, M.; Nozaki, M.; Kinoshita, A.; Tamaki, H.; Arita, M.; Saito, M.; Yamamoto, K.; Hachiya, T.; Noguchi, K.; Ueda, T.; Yagi, Y.; Kobayashi, T.; Nakamura, T.; Sato, Y.; Hirayama, T.; Sugiyama, M.
10.1101/2020.06.09.141382 — plant biology — Posted on 2020-06-12
3221 An SNP variant MT1-MMP with a defect in its collagenolytic activity confers the fibrotic phenotype of Dupuytren's Disease
Itoh, Y.; Ng, M.; Wiberg, A.; Inoue, K.; Hirata, N.; Paiva, K. B.; Ito, N.; Dzobo, K.; Sato, N.; Gifford, V.; Fijita, Y.; Inada, M.; Furniss, D.
10.1101/2020.06.09.142513 — biochemistry — Posted on 2020-06-12
3223 Harnessing endogenous repair mechanisms for targeted gene knock-in of bovine embryos
Owen, J. R.; Hennig, S. L.; McNabb, B. R.; Lin, J. C.; Young, A. E.; Murray, J. D.; Ross, P. J.; Van Eenennaam, A. L.
10.1101/2020.06.09.143115 — bioengineering — Posted on 2020-06-12
3225 Cell proliferation and migration explain pore bridging dynamics in 3D printed scaffolds of different pore size
Buenzli, P. R.; Lanaro, M.; Wong, C. S.; McLaughlin, M. P.; Allenby, M. C.; Woodruff, M. A.; Simpson, M. J.
10.1101/2020.03.12.989053 — bioengineering — Posted on 2020-06-12
3226 Synthetic biosensor circuits with a synchronous precision response to dynamic phytohormone inputs
Perez Garcia, S.; Garcia Navarrete, M.; Ruiz Sanchis, D.; Prieto Navarro, C.; Avdovic, M.; Pucciariello, O.; Wabnik, K.
10.1101/2020.05.31.125997 — synthetic biology — Posted on 2020-06-12
3227 A decade of epigenetic change in aging twins: genetic and environmental contributions to longitudinal DNA methylation
Reynolds, C. A.; Tan, Q.; Munoz, E.; Jylhava, J.; Hjelmborg, J.; Christiansen, L.; Hagg, S.; Pedersen, N. L.
10.1101/778555 — genetics — Posted on 2020-06-12
3229 TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting in situ assembly of mammalian ATP synthase proton channel
Bahri, H.; Buratto, J.; Rojo, M.; Dompierre, J. P.; Salin, B.; Blancard, C.; Cuvellier, S.; Rose, M.; Ben Ammar Elgaaied, A.; Tetaud, E.; di Rago, J.-P.; Devin, A.; Duvezin-Caubet, S.
10.1101/2020.04.03.023861 — cell biology — Posted on 2020-06-12
3230 Quantitative Measurements of Enlarged Perivascular Spaces in the Brain are Associated with Retinal Microvascular Parameters in Older Community-Dwelling Subjects
Ballerini, L.; McGrory, S.; Valdes-Hernandez, M.; Lovreglio, R.; Pellegrini, E.; MacGillivray, T.; Munoz Maniega, S.; Henderson, R.; Taylor, A.; Bastin, M.; Doubal, F.; Trucco, E.; Deary, I.; Wardlaw, J.
10.1101/822155 — neuroscience — Posted on 2020-06-12
3231 The long non-coding RNA lnc-HLX-2-7 is oncogenic in group 3 medulloblastomas
Katsushima, K.; Lee, B.; Kunhiraman, H.; Zhong, C.; Murath, R.; Ying, J.; Liu, B.; Garancher, A.; Monforte, H. L.; Gonzalez-Gomez, I.; Stapleton, S.; Vibhakar, R.; Bettegowda, C.; Wechsler-Reya, R. J.; Jallo, G.; Raabe, E.; Eberhart, C. G.; Perera, R. J.
10.1101/2020.06.08.140251 — cancer biology — Posted on 2020-06-12
3232 Visualization of the HIV-1 Env Glycan Shield Across Scales
Berndsen, Z. T.; Chakraborty, S.; Wang, X.; Cottrell, C. A.; Torres, J. L.; Diedrich, J. K.; Lopez, C.; Yates, J. R.; van-Gils, M. J.; Paulson, J. C.; Gnanakaran, S.; Ward, A. B.
10.1101/839217 — biophysics — Posted on 2020-06-12
3235 The regulatory landscape of early maize inflorescence development
Parvathaneni, R. K.; Bertolini, E.; Shamimuzzaman, M.; Vera, D.; Lung, P.-Y.; Rice, B. R.; Zhang, J.; Brown, P. J.; Lipka, A. E.; Bass, H. W.; Eveland, A. L.
10.1101/870378 — plant biology — Posted on 2020-06-12
3239 Epigenome-wide change and variation in DNA methylation from birth to late adolescence
Mulder, R. H.; Neumann, A. H.; Cecil, C. A.; Walton, E.; Houtepen, L. C.; Simpkin, A. J.; Rijlaarsdam, J.; Heijmans, B. T.; Gaunt, T. R.; Felix, J. F.; Jaddoe, V. W.; Bakermans-Kranenburg, M. J.; Tiemeier, H.; Relton, C. L.; van IJzendoorn, M. H.; Suderman, M.
10.1101/2020.06.09.142620 — genomics — Posted on 2020-06-12
3242 Unravelling the debate on heme effects in COVID-19 infections
Hopp, M.-T.; Domingo-Fernandez, D.; Gadiya, Y.; Detzel, M. S.; Schmalohr, B. F.; Steinbock, F.; Imhof, D.; Hofmann-Apitius, M.
10.1101/2020.06.09.142125 — bioinformatics — Posted on 2020-06-12
3249 Adipose Tissue is a Critical Regulator of Osteoarthritis
Collins, K. H.; Lenz, K. L.; Pollitt, E. N.; Ferguson, D.; Hutson, I.; Springer, L. E.; Oestreich, A. K.; Tang, R.; Choi, Y.-R.; Meyer, G. A.; Teitelbaum, S. L.; Pham, C. T. N.; Harris, C. A.; Guilak, F.
10.1101/2020.06.04.134601 — physiology — Posted on 2020-06-12
3250 Testing a convolutional neural network-based hippocampal segmentation method in a stroke population
Zavaliangos-Petropulu, A.; Tubi, M. A.; Haddad, E.; Zhu, A.; Braskie, M. N.; Jahanshad, N.; Thompson, P. M.; Liew, S.-L.
10.1101/2020.01.28.924068 — neuroscience — Posted on 2020-06-12
3253 Reverse-engineering Recurrent Neural Network solutions to a hierarchical inference task for mice
Schaeffer, R.; Khona, M.; Meshulam, L.; International Brain Laboratory, ; Fiete, I. R.
10.1101/2020.06.09.142745 — neuroscience — Posted on 2020-06-12
3254 FasR regulates fatty acid biosynthesis and is essential for virulence of Mycobacterium tuberculosis
Mondino, S.; Vazquez, C. L.; Cabruja, M.; Sala, C.; Cazenave-Gassiot, A.; Blanco, F. C.; Wenk, M. R.; Cole, S.; Bigi, F.; Gramajo, H.; Gago, G.
10.1101/2020.06.08.140004 — microbiology — Posted on 2020-06-12
3255 Phage infection mediates inhibition of bystander bacteria
Chatterjee, A.; Willett, J. L. E.; Dunny, G. M.; Duerkop, B. A.
10.1101/2020.05.11.077669 — microbiology — Posted on 2020-06-12
3257 ROBOCOV: An affordable open-source robotic platform for COVID-19 testing by RT-qPCR
Villanueva-Canas, J. L.; Gonzalez-Roca, E.; Gastaminza Unanue, A.; Titos, E.; Martinez Yoldi, M. J.; Vergara Gomez, A.; Puig Butille, J. A.
10.1101/2020.06.11.140285 — bioinformatics — Posted on 2020-06-12
3258 Signaling mechanism of phytochromes in solution
Isaksson, L.; Gustavsson, E.; Vrhovac, L.; Persson, C.; Brath, U.; Karlsson, G.; Orekhov, V.; Westenhoff, S.
10.1101/2020.04.05.025882 — biochemistry — Posted on 2020-06-12
3260 High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
Righetto, R. D.; Anton, L.; Adaixo, R.; Jakob, R. P.; Zivanov, J.; Mahi, M.-A.; Ringler, P.; Schwede, T.; Maier, T.; Stahlberg, H.
10.1101/2020.04.28.065599 — molecular biology — Posted on 2020-06-12
3261 Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank
Venkataraman, G. R.; Olivieri, J. E.; DeBoever, C.; Tanigawa, Y.; Justesen, J. M.; Dilthey, A.; Rivas, M. A.
10.1101/2020.05.28.119669 — genetics — Posted on 2020-06-12
3265 The seagrass methylome memorizes heat stress and is associated with variation in stress performance among clonal shoots
Jueterbock, A.; Boström, C.; Coyer, J. A.; Olsen, J. L.; Kopp, M.; Dhanasiri, A. K.; Smolina, I.; Arnaud-Haond, S.; Van de Peer, Y.; Hoarau, G.
10.1101/787754 — plant biology — Posted on 2020-06-12
3270 Cholesterol sensing by CD81 is important for hepatitis C virus entry
Palor, M.; Stejskal, L.; Mandal, P.; Lenman, A.; Alberione, P. M.; Kirui, J.; Moeller, R.; Ebner, S.; Meissner, F.; Gerold, G.; Shepherd, A. J.; Grove, J.
10.1101/542837 — molecular biology — Posted on 2020-06-12
3271 Insights into glycan import by a prominent gut symbiont
Gray, D.; White, J.; Oluwole, A.; Rath, P.; Glenwright, A.; Mazur, A.; Zahn, M.; Basle, A.; Morland, C.; Evans, S.; Cartmell, A.; Robinson, C. V.; Hiller, S.; Ranson, N.; Bolam, D.; van den Berg, B.
10.1101/2020.06.11.146753 — microbiology — Posted on 2020-06-12
3273 Bidirectional FtsZ filament treadmilling transforms lipid membranes via torsional stress
Ramirez-Diaz, D. A.; Merino-Salomon, A.; Meyer, F.; Heymann, M.; Rivas, G.; Bramkamp, M.; Schwille, P.
10.1101/587790 — biophysics — Posted on 2020-06-12
3274 Myosin-driven actin-microtubule networks exhibit self-organized contractile dynamics
Lee, G.; Rust, M. J.; Das, M.; McGorty, R. J.; Ross, J. L.; Robertson-Anderson, R. M.
10.1101/2020.06.11.146662 — biophysics — Posted on 2020-06-12
3275 Molecular characterization of the stress network in the human brain
Meijer, M.; Keo, A.; van Leeuwen, J. M. C.; Dzyubachyk, O.; Meijer, O. C.; Vinkers, C. H.; Mahfouz, A.
10.1101/661587 — neuroscience — Posted on 2020-06-12
3277 Deep sequencing reveals Campylobacter in commercial meat chickens less than 8 days old.
Colles, F. M.; Hedges, S. J.; Dixon, R.; Preston, S. G.; Thornhill, P.; Barfod, K. K.; Gebhardt-Henrich, S. G.; Creach, P.; Maiden, M. C.; Stamp Dawkins, M.; Smith, A. L.
10.1101/2020.06.10.141978 — microbiology — Posted on 2020-06-12
3279 Loss of TP53 mediates suppression of Macrophage Effector Function via Extracellular Vesicles and PDL1 towards Resistance against Chemoimmunotherapy in B-cell malignancies
Izquierdo, E.; Vorholt, D.; Sackey, B.; Nolte, J.; Blakemore, S. J.; Schmitz, J.; Barbarino, V.; Nickel, N.; Bachurski, D.; Lobastova, L.; Nikolic, M.; Michalik, M.; Brinker, R.; Neuhaus, R.; Frenzel, L.; Koch, M.; Knittel, G.; Reinhardt, H. C.; Peifer, M.; Rebollido-Rios, R.; Bruns, H.; Krueger, M.; Hallek, M.; Pallasch, C.
10.1101/2020.06.11.145268 — cell biology — Posted on 2020-06-12
3280 In vivo characterisation of endogenous cardiovascular extracellular vesicles in larval and adult zebrafish
Scott, A.; Sueiro Ballesteros, L.; Bradshaw, M.; Power, A.; Lorriman, J.; Love, J.; Paul, D.; Herman, A.; Emanueli, C.; Richardson, R. J.
10.1101/742692 — cell biology — Posted on 2020-06-12
3281 Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi:β-arrestin complexes
Zheng, K. Z.; Smith, J. S.; Warman, A.; Choi, I.; Gundry, J.; Pack, T. F.; Inoue, A.; Caron, M.; Rajagopal, S.
10.1101/2020.06.11.146605 — biochemistry — Posted on 2020-06-12
3284 Tau pathology in early Alzheimer's disease disrupts selective neurophysiological network dynamics
Kocagoncu, E.; Quinn, A.; Firouzian, A.; Cooper, E.; Greve, A.; Gunn, R.; Green, G.; Woolrich, M. W.; Henson, R. N.; Lovestone, S.; Deep and Frequent Phenotyping study team, ; Rowe, J. B.
10.1101/524355 — neuroscience — Posted on 2020-06-12
3285 TIP60 acetylates H2AZ and regulates doxorubicin-induced DNA damage sensitivity through RAD51 transcription
Lee, K. K.; Zhang, Y.; Magallanes, R. T.; Rajagopalan, D.; Bhatia, S. S.; Ng, L.; Desi, N.; Tham, C. Y.; Teo, W. S.; Hoppe, M. M.; Jeyasekharan, A.; Tay, Y.; Chng, W. J.; Tenen, D. G.; Benoukraf, T.; Jha, S.
10.1101/2020.06.10.145193 — molecular biology — Posted on 2020-06-12
3287 Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma
Geistlinger, L.; Oh, S.; Ramos, M.; Schiffer, L.; LaRue, R.; Henzler, C.; Munro, S.; Daughters, C.; Nelson, A. C.; Winterhoff, B.; Chang, Z.; Talukda, S.; Shetty, M.; Mullany, S.; Morgan, M.; Parmigiani, G.; Birrer, M.; Qin, L.-X.; Riester, M.; Starr, T.; Waldron, L.
10.1101/554394 — cancer biology — Posted on 2020-06-12
3289 Sex-dependent effects of chronic exercise on cognitive flexibility in aging mice
Short, A. K.; Bui, V.; Zbukvic, I. C.; Hannan, A. J.; Pang, T. Y.; Kim, J. H.
10.1101/2020.06.10.145136 — neuroscience — Posted on 2020-06-11
3290 IPSE, a Parasite-Derived, Host Immunomodulatory Infiltrin Protein, Alleviates Resiniferatoxin-Induced Bladder Pain
Ishida, K.; Mbanefo, E.; Le, L.; Lamanna, O.; Pennington, L.; Finkel, J.; Jardetzky, T.; Falcone, F.; Hsieh, M.
10.1101/2020.06.11.146829 — neuroscience — Posted on 2020-06-12
3292 Critical role of WNK1 in MYC-dependent early thymocyte development
Köchl, R.; Vanes, L.; Llorian Sopena, M.; Chakravarty, P.; Hartweger, H.; Fountain, K.; White, A.; Cowan, J.; Anderson, G.; Tybulewicz, V.
10.1101/2020.06.11.147017 — immunology — Posted on 2020-06-12
3294 Co-occurrence history increases ecosystem temporal stability and recovery from a flood in experimental plant communities
van Moorsel, S. J.; Hahl, T.; Petchey, O. L.; Ebeling, A.; Eisenhauer, N.; Schmid, B.; Wagg, C.
10.1101/262337 — ecology — Posted on 2020-06-12
3295 AdipoR2 is Essential for Membrane Lipid Homeostasis in Response to Dietary Saturated Fats
Devkota, R.; Ruiz, M.; Palmgren, H.; Stahlman, M.; Maresca, M.; Jaiswal, H.; Bohlooly-Y, M.; Peng, X.-R.; Boren, J.; Pilon, M.
10.1101/2020.06.11.144329 — cell biology — Posted on 2020-06-11
3300 Phox2a defines a developmental origin of the anterolateral system in mice and humans
Roome, R. B.; Bourojeni, F. B.; Mona, B.; Rastegar-Pouyani, S.; Blain, R.; Dumouchel, A.; Salesse, C.; Thompson, W. S.; Brookbank, M.; Gitton, Y.; Tessarollo, L.; Goulding, M.; Johnson, J. E.; Kmita, M.; Chedotal, A.; Kania, A.
10.1101/2020.06.10.144659 — neuroscience — Posted on 2020-06-11
3301 Assembly intermediates of orthoreovirus captured in the cell
Sutton, G.; Sun, D.; Fu, X.; Kotecha, A.; Hecksel, C. W.; Clare, D. K.; zhang, p.; Stuart, D. I.; Boyce, M.
10.1101/2020.06.10.144998 — microbiology — Posted on 2020-06-11
3303 Life-long persistence of infectious Zika virus: Inflammation and behavioral sequela
Ireland, D. D.; Manangeeswaran, M.; Lewkowicz, A.; Engel, K.; Clark, S. M.; Laniyan, A.; Sykes, J.; Lee, H. N.; McWilliams, I. L.; Kelly-Baker, L.; Tonnelli, L. H.; Verthelyi, D.
10.1101/2020.06.11.145854 — neuroscience — Posted on 2020-06-11
3306 Diatom Modulation of Microbial Consortia Through Use of Two Unique Secondary Metabolites
Shibl, A. A.; Isaac, A.; Ochsenkühn, M. A.; Cardenas, A.; Fei, C.; Behringer, G.; Arnoux, M.; Drou, N.; Santos, M. P.; Gunsalus, K. C.; Voolstra, C. R.; Amin, S. A.
10.1101/2020.06.11.144840 — microbiology — Posted on 2020-06-11
3308 Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2
Rosenke, K.; Jarvis, M.; Feldmann, F.; Schwarz, B.; Okumura, A.; Lovaglio, J.; Saturday, G.; Hanley, P.; Meade-White, K.; Williamson, B.; Hansen, F.; Perez-Perez, L.; Leventhal, S.; Tang-Huau, T.-L.; Nason, M.; Callison, J.; Haddock, E.; Scott, D.; Sewell, G.; Bosio, C.; Hawman, D.; de Wit, E.; Feldmann, H.
10.1101/2020.06.10.145144 — pharmacology and toxicology — Posted on 2020-06-11
3310 Biosynthesis and chemical characterization of an intracellular red pigment of Talaromyces islandicus T101
Rodrigues, I. V. P.; Borges, K. R. A.; da Cruz, N.; Teles, A. M.; da Silva, M. A. C. N.; Alves, R. d. N. S.; de Andrade, M. S.; Khayat, A. S.; Pinho, J. D.; Vale, A. A. M.; Guimaraes, S. J. A.; Ruiz, J. C.; Nascimento, M. d. D. S. B.; Bezerra, G. F. d. B.
10.1101/2020.06.11.145821 — microbiology — Posted on 2020-06-11
3311 Inhibition of Anti-viral Stress Granule Formation by infectious bronchitis virus endoribonuclease nsp15 Ensures Efficient Virus Replication
Liao, Y.; Gao, B.; Gong, X.; Fang, S.; Weng, W.; Sun, Y.; Meng, C.; Tan, L.; Song, C.; Qiu, X.; Liu, W.; Forlenza, M.; Ding, C.
10.1101/2020.06.11.145862 — microbiology — Posted on 2020-06-11
3315 SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness
Corbett, K. S.; Edwards, D.; Leist, S. R.; Abiona, O. M.; Boyoglu-Barnum, S.; Gillespie, R. A.; Himansu, S.; Schafer, A.; Ziwawo, C. T.; DiPiazza, A. T.; Dinnon, K. H.; Elbashir, S. M.; Shaw, C. A.; Woods, A.; Fritch, E. J.; Martinez, D. R.; Bock, K. W.; Minai, M.; Nagata, B. M.; Hutchinson, G. B.; Bahl, K.; Garcia-Dominguez, D.; Ma, L.; Renzi, I.; Kong, W.-P.; Schmidt, S. D.; Wang, L.; Zhang, Y.; Stevens, L. J.; Phung, E.; Chang, L. A.; Loomis, R. J.; Altaras, N. E.; Narayanan, E.; Metkar, M.; Presnyak, V.; Liu, C.; Louder, M. K.; Shi, W.; Leung, K.; Yang, E. S.; West, A.; Gully, K. L.; Wang,
10.1101/2020.06.11.145920 — immunology — Posted on 2020-06-11
3318 Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region
Carino, A.; Moraca, F.; Fiorillo, B.; Marcano, S.; Sepe, V.; Biagioli, M.; Finamore, C.; Bozza, S.; Francisci, D.; Distrutti, E.; Catalanotti, B.; Zampella, A.; Fiorucci, S.
10.1101/2020.06.10.144964 — pharmacology and toxicology — Posted on 2020-06-11
3320 Shielding and Beyond: The Roles of Glycans in SARS-CoV-2 Spike Protein
Casalino, L.; Gaieb, Z.; Dommer, A. C.; Harbison, A. M.; Fogarty, C. A.; Barros, E. P.; Taylor, B. C.; Fadda, E.; Amaro, R. E.
10.1101/2020.06.11.146522 — biophysics — Posted on 2020-06-11
3321 ROBOCOV: An affordable open-source robotic platform for COVID-19 testing by RT-qPCR
Villanueva-Canas, J. L.; Gonzalez-Roca, E.; Gastaminza Unanue, A.; Titos, E.; Martinez Yoldi, M. J.; Vergara Gomez, A.; Puig Butille, J. A.
10.1101/2020.06.11.140285 — bioinformatics — Posted on 2020-06-11
3322 Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived intestinal organoids
Krueger, J.; Gross, R.; Conzelmann, C.; Mueller, J. A.; Koepke, L.; Sparrer, K.; Schuetz, D.; Seufferlein, T.; Barth, T. F. E.; Stenger, S.; Heller, S.; Kleger, A.; Muench, J.
10.1101/2020.06.10.144816 — microbiology — Posted on 2020-06-11
3326 Dmp1Cre-directed knockdown of PTHrP in murine decidua is associated with increased bone width and a life-long increase in strength specific to male progeny
Ansari, N.; Isojima, T.; Crimeen-Irwin, B.; Poulton, I. J.; McGregor, N. E.; Ho, P. M.; Kovacs, C. S.; Dimitriadis, E.; Gooi, J. H.; Martin, T. J.; Sims, N. A.
10.1101/2020.06.09.141812 — cell biology — Posted on 2020-06-11
3328 Chitosan induces plant hormones and defences in tomato root exudates
Suarez-Fernandez, M.; Marhuenda-Egea, F. C.; Lopez-Moya, F.; Arnao, M. B.; Cabrera-Escribano, F.; Nueda, M. J.; Gunse, B.; Lopez-Llorca, L. V.
10.1101/2020.06.09.142653 — plant biology — Posted on 2020-06-11
3331 Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis
Li, G.; Huang, H.; Fan, S.; Zhou, X.; Liu, Y.; Li, X.; Liao, L.; Huang, J.; Shi, C.; Yu, L.; Fu, R.; Fan, J.; Zhang, Y.; Luo, C.; Li, G.
10.1101/2020.06.09.141655 — animal behavior and cognition — Posted on 2020-06-11
3332 Molecular mechanism of SARS-Cov-2 components caused ARDS in murine model
Gu, T.; Zhao, S.; Jin, G.; Song, M.; Zhi, Y.; Zhao, R.; Ma, F.; Zheng, Y.; Wang, K.; Liu, H.; Xin, M.; Li, X.; Dong, C. D.; Liu, K.; Dong, Z.
10.1101/2020.06.07.119032 — pathology — Posted on 2020-06-11
3333 Compensation of physiological motion enables high-yield whole-cell recording in vivo
Stoy, W. M.; Yang, B.; Kight, A.; Wright, N. C.; Borden, P. Y.; Stanley, G. B.; Forest, C. R.
10.1101/2020.06.09.143008 — neuroscience — Posted on 2020-06-11
3336 Single cell transfection of human induced pluripotent stem cells using a droplet-based microfluidic system.
Perez, C.; Sanluis-Verdes, A.; Waisman, A.; Lombardi, A.; ROSERO, G.; La Greca, A.; Bhansali, S.; Bourguignon, N.; Luzzani, C.; Perez, M.; Miriuka, S.; Lerner, B.
10.1101/2020.06.09.143214 — bioengineering — Posted on 2020-06-11
3337 Transcriptome analysis uncovers distinct modes of epigenetic gene changes in early versus late stages of amyloid-β induced Alzheimer's disease pathology
Zhang, H.; Karisetty, B. C.; Bhatnagar, A.; Armour, E. M.; Beaver, M.; Roach, T. V.; Mortazavi, S.; Mandloi, S.; Elefant, F.
10.1101/2020.06.09.142885 — neuroscience — Posted on 2020-06-11
3338 Thiamine pyrophosphokinase deficiency induces Alzheimer's pathology
Sang, S.; Qian, T.; Cai, F.; Qiu, H.; Xu, Y.; Zhang, Y.; Zhang, Q.; Huang, S.; Jiang, D.; Wu, Y.; Tong, H.; Pan, X.; Wang, C.; Cheng, X.; Zhong, K.; Guan, Y.; Zhu, M. X.; Yu, X.; Song, W.; Zhong, C.
10.1101/2020.06.09.141358 — neuroscience — Posted on 2020-06-11
3340 Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium
Carter, L. E.; Cook, D. P.; McCloskey, C. W.; Dang, T.; Collins, O.; Gamwell, L. F.; Dempster, H. A.; Vanderhyden, B. C.
10.1101/2020.06.10.145045 — cell biology — Posted on 2020-06-11
3341 Macrophage-mediated antibody dependent effector function in aggressive B-cell lymphoma treatment is enhanced by Ibrutinib via inhibition of JAK2
Barbarino, V.; Henschke, S.; Blakemore, S.; Izquierdo, E.; Michalik, M.; Brinker, R.; Nickel, N.; Moellenkotte, I.; Vorholt, D.; Fedorchenko, O.; Mikhael, N.; Seeger-Nukpezah, T.; Hallek, M.; Pallasch, C. P.
10.1101/2020.06.10.135632 — cancer biology — Posted on 2020-06-11
3346 Host environmental conditions induce small fungal cell size and alter population heterogeneity in Cryptococcus neoformans
Zhou, X.; Zafar, H.; Sephton-Clark, P. C. S.; Mohamed, S. H.; Chapuis, A.; Makarova, M.; MacCallum, D. M.; Drummond, R.; Dambuza, I. M.; Ballou, E. R.
10.1101/2020.01.03.894709 — microbiology — Posted on 2020-06-11
3351 A novel virus alters gene expression and vacuolar morphology in Malassezia cells and induces a TLR3-mediated inflammatory immune response
Park, M.; Cho, Y.-J.; Kim, D.; Yang, C.-S.; Lee, S. M.; Dawson, T.; Nakamizo, S.; Kabashima, K.; Lee, Y. W.; Jung, W. H.
10.1101/2019.12.17.880526 — microbiology — Posted on 2020-06-11
3355 Mucin-derived O-glycans supplemented to diet mitigate diverse microbiota perturbations
Pruss, K. M.; Marcobal, A.; Southwick, A.; Dahan, D.; Smits, S.; Ferreyra, J.; Higginbottom, S.; Sonnenburg, E.; Kashyap, P.; Choudhury, B.; Bode, L.; Sonnenburg, J.
10.1101/2020.06.09.140897 — microbiology — Posted on 2020-06-11
3356 Towards robust and replicable sex differences in the intrinsic brain function of autism
Floris, D. L.; Filho, J. O. A.; Lai, M.-C.; Giavasis, S.; Oldehinkel, M.; Mennes, M.; Charman, T.; Tillmann, J.; Dumas, G.; Ecker, C.; Dell'Acqua, F.; Banaschewski, T.; Moessnang, C.; Baron-Cohen, S.; Durston, S.; Loth, E.; Murphy, D. G.; Buitelaar, J. K.; Beckmann, C.; Milham, M.; Di Martino, A.
10.1101/2020.06.09.142471 — neuroscience — Posted on 2020-06-11
3357 Biased Auditory Nerve Central Synaptopathy Exacerbates Age-related Hearing Loss
Wang, M.; Zhang, C.; Lin, S.; Wang, Y.; Seicol, B. J.; Ariss, R. W.; Xie, R.
10.1101/2020.06.09.142737 — neuroscience — Posted on 2020-06-11
3358 Reverse-engineering Recurrent Neural Network solutions to a hierarchical inference task for mice
Schaeffer, R.; Khona, M.; Meshulam, L.; International Brain Laboratory, ; Fiete, I. R.
10.1101/2020.06.09.142745 — neuroscience — Posted on 2020-06-11
3361 Mendelian randomization identifies folliculin expression as a mediator of diabetic retinopathy.
Skol, A. D.; Jung, S. C.; Sokovic, A. M.; Chen, S.; Fazal, S.; Sosina, O.; Borkar, P. P.; Lin, A.; Sverdlov, M.; Cao, D.; Swaroop, A.; Bebu, I.; DCCT/EDIC Study Group, ; Stranger, B.; Grassi, M. A.
10.1101/2020.06.09.143164 — genomics — Posted on 2020-06-11
3362 Speeding up the detection of invasive aquatic species using environmental DNA and nanopore sequencing
Egeter, B.; Verissimo, J.; Lopes_Lima, M.; Chaves, C.; Pinto, J.; Riccardi, N.; Beja, P.; Fonseca, N. A.
10.1101/2020.06.09.142521 — ecology — Posted on 2020-06-11
3363 Functional melanoma cell heterogeneity is regulated by MITF-dependent cell-matrix interactions
Spoerri, L.; Tonnessen-Murray, C. A.; Gunasingh, G.; Hill, D. S.; Beaumont, K. A.; Jurek, R. J.; Vanwalleghem, G. C.; Fane, M. E.; Daignault, S. M.; Matigian, N.; Scott, E. K.; Smith, A. G.; Stehbens, S. J.; Schaider, H.; Weninger, W.; Gabrielli, B.; Haass, N. K.
10.1101/2020.06.09.141747 — cancer biology — Posted on 2020-06-11
3367 A Mesoscale Finite Element Modelling Approach for Understanding Brain Morphology and Material Heterogeneity Effects in Chronic Traumatic Encephalopathy
Bakhtiarydavijani, A.; Khalid, G. A.; Murphy, M. a.; Johnson, K. L.; Peterson, L. E.; Dobbins, A. C.; Horstemeyer, M. F.; Jones, M.; Prabhu, R. K.
10.1101/2020.06.09.141259 — biophysics — Posted on 2020-06-11
3368 Sound generation in zebrafish with Bio-Opto-Acoustics (BOA)
Favre-Bulle, I. A.; Taylor, M.; Marquez-Legorreta, E.; Vanwalleghem, G.; Poulsen, R. E.; Rubinzstein-Dunlop, H.; Scott, E.
10.1101/2020.06.09.143362 — biophysics — Posted on 2020-06-11
3373 Speech-in-noise intelligibility difficulties with age: the role of cochlear synaptopathy
Garrett, M.; Vasilkov, V.; Mauermann, M.; Wilson, J. L.; Henry, K. S.; Verhulst, S.
10.1101/2020.06.09.142950 — neuroscience — Posted on 2020-06-11
3380 CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent CNS autoimmunity
Manouchehri, N.; Hussain, R.; Cravens, P.; Edelson, B.; Wu, G.; Cross, A.; Doelger, R.; Loof, N.; Eagar, T.; Forsthuber, T.; Calvier, L.; Herz, J.; Stuve, O.
10.1101/2020.06.10.144956 — immunology — Posted on 2020-06-11
3381 Comparison of manual and automated ventricle segmentation in the maternal immune stimulation rat model of schizophrenia
Winter, R.; Akinola, B.; Barroeta-Hlusicka, E.; Meister, S.; Winter, C.; Pietzsch, J.; Bernhardt, N.
10.1101/2020.06.10.144022 — neuroscience — Posted on 2020-06-11
3383 Noradrenaline modulates tabula-rasa exploration
Dubois, M.; Habicht, J.; Michely, J.; Moran, R.; Dolan, R.; Hauser, T.
10.1101/2020.02.20.958025 — neuroscience — Posted on 2020-06-11
3384 Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses
Scekic-Zahirovic, J.; Sanjuan-Ruiz, I.; Kan, V.; Megat, S.; de Rossi, P.; Dieterle, S.; Cassel, R.; Kessler, P.; Wiesner, D.; Tzeplaeff, L.; Demais, V.; Mueller, H.-P.; Picchiarelli, G.; Mishra, N.; Dirrig-Grosch, S.; Kassubek, J.; Rasche, V.; Ludolph, A. C.; Boutillier, A.-L.; Polymenidou, M.; Lagier-Tourenne, C.; Liebscher, S.; Dupuis, L.
10.1101/2020.06.09.141556 — neuroscience — Posted on 2020-06-11
3386 NF45/NF90-mediated rDNA transcription provides a novel target for immunosuppressant development
Hsiang-i, T.; Zeng, X.; Liu, L.; Xin, S.; Wu, Y.; Xu, Z.; Liu, G.; Bi, Z.; Su, D.; Yang, M.; Wang, C.; Zhao, J.; Eriksson, J. E.; Deng, W.; Cheng, F.; Chen, H.
10.1101/2020.05.26.116897 — molecular biology — Posted on 2020-06-11
3389 Dichloroacetate improves hepatic and systemic energy metabolism during sepsis
Mainali, R.; Zabalwi, M.; Long, D.; Buechler, N.; Jain, S.; Quillen, E.; Key, C.-C.; Zhu, X.; Stacpoole, P.; Martinez, J.; McCall, C. E.; Quinn, M. A.
10.1101/2020.06.09.142430 — immunology — Posted on 2020-06-11
3391 Single nucleus multi-omics regulatory atlas of the murine pituitary
Ruf-Zamojski, F. M.; Zhang, Z.; Zamojski, M.; Smith, G. R.; Mendelev, N.; Liu, H.; Nudelman, G.; Moriwaki, M.; Pincas, H.; Gomez Castanon, R.; Nair, V. D.; Seenarine, N.; Amper, M. A. S.; Zhou, X.; Ongaro, L.; Toufaily, C.; Schang, G.; Nery, J. R.; Bartlett, A.; Aldridge, A.; Jain, N.; Childs, G. V.; Troyanskaya, O. G.; Ecker, J. R.; Turgeon, J. L.; Welt, C. K.; Bernard, D. J.; Sealfon, S. C.
10.1101/2020.06.06.138024 — cell biology — Posted on 2020-06-11
3392 Quantifying the role of mechanics in the free and encapsulated growth of cancer spheroids
Urcun, S.; Rohan, P.-Y.; Skalli, W.; Nassoy, P.; Bordas, S. P. A.; Sciume, G.
10.1101/2020.06.09.142927 — biophysics — Posted on 2020-06-11
3393 AStarix: Fast and Optimal Sequence-to-Graph Alignment
Ivanov, P.; Bichsel, B.; Mustafa, H.; Kahles, A.; Rätsch, G.; Vechev, M.
10.1101/2020.01.22.915496 — bioinformatics — Posted on 2020-06-11
3395 Development of genetic tools for the thermophilic filamentous fungus Thermoascus aurantiacus
Gabriel, R.; Prinz, J.; Jecmenica, M.; Romero-Vazquez, C.; Chou, P.; Harth, S.; Floerl, L.; Curran, L.; Oostlander, A.; Matz, L.; Fritsche, S.; Gorman, J.; Schuerg, T.; Fleissner, A.; Singer, S. W.
10.1101/2020.06.09.143198 — microbiology — Posted on 2020-06-11
3396 Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger Cyclin K degradation
Lv, L.; Chen, P.; Cao, L.; Li, Y.; Zeng, Z.; Cui, Y.; Wu, Q.; Li, J.; Wang, J.-H.; Dong, M.-Q.; Qi, X.; Han, T.
10.1101/2020.06.10.144303 — biochemistry — Posted on 2020-06-11
3399 Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways
Ye, L.; Bae, M.; Cassilly, C. D.; Jabba, S. V.; Lu, H.-Y.; Wang, J.; Thompson, J. D.; Lickwar, C. R.; Poss, K. D.; Jordt, S.-E.; Clardy, J.; Liddle, R. A.; Rawls, J. F.
10.1101/2020.06.09.142133 — physiology — Posted on 2020-06-10
3400 Frequency-independent biological signal identification (FIBSI): A free program that simplifies intensive analysis of non-stationary time series data
Cassidy, R. M.; Bavencoffe, A. G.; Lopez, E. R.; Cheruvu, S. S.; Walters, E. T.; Uribe, R. A.; Krachler, A. M.; Odem, M. A.
10.1101/2020.05.29.123042 — physiology — Posted on 2020-06-11
3402 Hippocampal hyperactivity in a rat model of Alzheimers disease
Sosulina, L.; Mittag, M.; Geis, H.-R.; Hoffmann, K.; Klyubin, I.; Qi, Y.; Steffen, J.; Friedrichs, D.; Henneberg, N.; Fuhrmann, F.; Justus, D.; Keppler, K.; Cuello, A. C.; Rowan, M.; Fuhrmann, M.; Remy, S.
10.1101/2020.06.09.141598 — neuroscience — Posted on 2020-06-10
3403 Pathway-specific deregulation of striatal excitatory synapses in LRRK2 mutations
Chen, C.; Soto, G.; Bannon, N.; Kang, S.; Kozorovitskiy, Y.; Parisiadou, L.
10.1101/2020.01.03.894410 — neuroscience — Posted on 2020-06-10
3406 Circadian Rhythm Analysis Using Wearable Device Data: A Novel Penalized Machine Learning Approach
Li, X.; Kane, M.; Zhang, Y.; Sun, W.; Song, Y.; Dong, S.; Lin, Q.; Zhu, Q.; Jiang, F.; Zhao, H.
10.1101/2020.02.20.957076 — neuroscience — Posted on 2020-06-11
3408 SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways
Serbyn, N.; Bagdiul, I.; Michel, A. H.; Suhandynata, R. T.; Zhou, H.; Kornmann, B.; Stutz, F.
10.1101/2020.06.08.140079 — molecular biology — Posted on 2020-06-10
3409 A Prokaryotic Membrane Sculpting BAR Domain Protein
Phillips, D. A.; Zacharoff, L. A.; Hampton, C. M.; Chong, G. W.; Malanoski, A. P.; Metskas, L. A.; Xu, S.; Bird, L. J.; Eddie, B. J.; Jensen, G. J.; Drummy, L. F.; El-Naggar, M. Y.; Glaven, S. M.
10.1101/2020.01.30.926147 — microbiology — Posted on 2020-06-10
3410 Ozone nanobubble treatment effectively reduced pathogenic Gram positive and negative bacteria in freshwater and safe for tilapia
Jhunkeaw, C.; Khongcharoen, N.; Rungrueng, N.; Sangpo, P.; Panphut, W.; Thapinta, A.; Senapin, S.; St-Hilaire, S.; Dong, H. T.
10.1101/2020.06.07.138297 — microbiology — Posted on 2020-06-10
3411 Bacterial protein domains with a novel Ig-like fold bind human CEACAM receptors
van Sorge, N. M.; Bonsor, D. A.; Deng, L.; Lindahl, E.; Schmitt, V.; Lyndin, M.; Schmidt, A.; Nilsson, O. R.; Brizuela, J.; Boero, E.; Sundberg, E. J.; van Strijp, J.; Doran, K. S.; Singer, B. S.; Lindahl, G.; McCarthy, A. J.
10.1101/2020.06.09.141622 — microbiology — Posted on 2020-06-11
3412 LILRB3 (ILT5) is a myeloid checkpoint on myeloid cells that elicits profound immununomodulation
Yeboah, M.; Papagregoriou, C.; Jones, D. C.; Chan, H. T. C.; Hu, G.; McPartlan, J. S.; Schiott, T.; Mattson, U.; Mockridge, C. I.; Tornberg, U.-C.; Hambe, B.; Ljungars, A.; Mattsson, M.; Tews, I.; Glennie, M. J.; Thirdborough, S. M.; Trowsdale, J.; Frendeus, B.; Chen, J.; Cragg, M. S.; Roghanian, A.
10.1101/2020.06.04.135400 — immunology — Posted on 2020-06-10
3413 Rhesus macaques as a tractable physiological model of human ageing
Chiou, K. L.; Montague, M. J.; Goldman, E. A.; Watowich, M. M.; Sams, S. N.; Song, J.; Horvath, J. E.; Sterner, K. N.; Ruiz-Lambides, A. V.; Martinez, M. I.; Higham, J. P.; Brent, L. J.; Platt, M. L.; Snyder-Mackler, N.
10.1101/2020.06.10.143669 — genomics — Posted on 2020-06-11
3415 Germline inherited small RNAs clear untranslated maternal mRNAs in C. elegans embryos
Quarato, P.; Singh, M.; Cornes, E.; Li, B.; Bourdon, L.; Mueller, F.; Didier, C.; Cecere, G.
10.1101/2020.02.03.919597 — developmental biology — Posted on 2020-06-10
3416 Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung
Reyes de Mochel, N.; Cheong, K. N.; Cassandras, M.; Wang, C.; Krasilnikov, M.; Matatia, P.; Molofsky, A.; Campisi, J.; PENG, T.
10.1101/2020.06.10.142893 — cell biology — Posted on 2020-06-10
3418 A comprehensive and centralized database for exploring omics data in Autoimmune Diseases
Martorell-Marugan, J.; Lopez-Dominguez, R.; Garcia-Moreno, A.; Toro-Dominguez, D.; Villatoro-Garcia, J. A.; Barturen, G.; Martin-Gomez, A.; Troule, K.; Gomez-Lopez, G.; Al-Shahrour, F.; Pena-Chilet, M.; Dopazo, J.; Gonzalez-Rumayor, V.; Alarcon-Riquelme, M. E.; Carmona-Saez, P.
10.1101/2020.06.10.144972 — bioinformatics — Posted on 2020-06-11
3424 Single-cell metabolic dynamics of early activated CD8 T cells during the primary immune response to infection
Levine, L. S.; Hiam, K. J.; Marquez, D. M.; Tenvooren, I.; Contreras, D. C.; Rathmell, J. C.; Spitzer, M. H.
10.1101/2020.01.21.911545 — immunology — Posted on 2020-06-10
3434 SAMHD1 mutations in mantle cell lymphoma: identification as disease driver conferring in vitro resistance to nucleoside analogues
Bühler, M. M.; Lu, J.; Scheinost, S.; Nadeu, F.; Roos-Weil, D.; Hensel, M.; Thavayogarajah, T.; Moch, H.; Manz, M. G.; Haralambieva, E.; Marques Maggio, E.; Bea, S.; Gine, E.; Campo, E.; Bernard, O. A.; Huber, W.; Zenz, T.
10.1101/2020.06.09.140376 — cancer biology — Posted on 2020-06-10
3437 Unravelling the debate on heme effects in COVID-19 infections
Hopp, M.-T.; Domingo-Fernandez, D.; Gadiya, Y.; Detzel, M. S.; Schmalohr, B. F.; Steinbock, F.; Imhof, D.; Hofmann-Apitius, M.
10.1101/2020.06.09.142125 — bioinformatics — Posted on 2020-06-10
3438

The low-density lipoprotein receptor-related protein-1 is essential for Dengue virus infection

Huerta Galindo, V.; Martin, A. M.; Sarria, M.; Guirola, O.; Yero, A.; Ramos, Y.; Pupo, D.; Martin, D.; Marcello, A.; Chinea, G.
10.1101/2020.06.10.144089 — biochemistry — Posted on 2020-06-10
3440 Functional modules from variable genes: Leveraging percolation to analyze noisy, high-dimensional data
Werner, S.; Rozemuller, M.; Ebbing, A.; Alemany, A.; Traets, J.; van Zon, J. S.; van Oudenaarden, A.; Korswagen, H. C.; Stephens, G. J.; Shimizu, T. S.
10.1101/2020.06.10.143743 — systems biology — Posted on 2020-06-10
3442 Lentiviral interleukin-10 gene therapy preserves fine motor circuitry and function after a cervical spinal cord injury in male and female mice
Chen, J. Y.; Fu, E. J.; Patel, P. R.; Sawan, H. A.; Moss, K. A.; Hostetler, A. J.; Hocevar, S. E.; Smith, D. R.; Anderson, A. J.; Chestek, C. A.; Shea, L. D.
10.1101/2020.06.05.137257 — neuroscience — Posted on 2020-06-10
3443 Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels
Feltham, J. E.; Xi, S.; Murray, S. C.; Wouters, M.; Urdiain-Arraiza, J.; Heilig, R.; George, C.; Townley, A. F.; Roberts, E.; Kessler, B. M.; Liberatori, S.; Charles, P. D.; Angel, A.; Fischer, R.; Mellor, J.
10.1101/833921 — molecular biology — Posted on 2020-06-10
3444 INNATE IMMUNE INTERFERENCE ATTENUATES INFLAMMATION IN BACILLUS ENDOPHTHALMITIS
Mursalin, M. H.; Coburn, P. S.; Miller, F. C.; Livingston, E.; Astley, R.; Callegan, M.
10.1101/2020.06.10.144915 — microbiology — Posted on 2020-06-10
3452 Monocyte-specific changes in gene expression implicate LACTB2 and PLIN2 in Alzheimer's disease.
Harwood, J. C.; Leonenko, G.; Sims, R.; Escott-Price, V.; Williams, J.; Holmans, P.
10.1101/2020.06.05.136275 — neuroscience — Posted on 2020-06-10
3453 Multiple types of navigational information are diffusely and independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-06-10
3454 A P2rx7 passenger mutation affects the vitality and function of immune cells in P2X4ko and other transgenic mice
Er-Lukowiak, M.; Duan, Y.; Rassendren, F.; Ulmann, L.; Nicke, A.; Ufer, F.; Friese, M. A.; Koch-Nolte, F.; Magnus, T.; Rissiek, B.
10.1101/2020.06.10.139410 — immunology — Posted on 2020-06-10
3455 Human Whole Genome Sequencing in South Africa
Glanzmann, B.; Jooste, T.; Ghoor, S.; Gordon, R.; Mia, R.; Mao, R.; Li, H.; Charls, P.; Douman, C.; Kotze, M.; Peeters, A.; Loots, G.; Esser, M.; Tiemessen, C.; Wilkinson, R.; Louw, J.; Gray, G.; Warren, R.; Moller Moller, M.; Kinnear, C.
10.1101/2020.06.10.144402 — genomics — Posted on 2020-06-10
3458 AP-2γ is Required for Maintenance of Pluripotent Mammary Stem Cells
Gu, V. W.; Cho, E.; Thompson, D. T.; Cassady, V. C.; Borcherding, N.; Koch, K. E.; Wu, V. T.; Lorenzen, A. W.; Kulak, M. V.; Williams, T.; Zhang, W.; Weigel, R. J.
10.1101/2020.06.10.107078 — developmental biology — Posted on 2020-06-10
3459 Multiscale activity imaging in the mammary gland reveals how oxytocin enables lactation
Stevenson, A. J.; Vanwalleghem, G.; Stewart, T. A.; Condon, N. D.; Lloyd-Lewis, B.; Marino, N.; Putney, J. W.; Scott, E. K.; Ewing, A. D.; Davis, F. M.
10.1101/657510 — cell biology — Posted on 2020-06-10
3462 Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes
Mahalingan, K. K.; Keenan, E. K.; Strickland, M.; Li, Y.; Liu, Y.; Ball, H. L.; Tanner, M. E.; Tjandra, N.; Roll-Mecak, A.
10.1101/2020.06.07.139295 — biochemistry — Posted on 2020-06-10
3463 The linear ubiquitin chain assembly complex generates heterotypic ubiquitin chains
Carvajal, A. R.; Diaz, C. G.; Vogel, A.; Sonn-Segev, A.; Schodl, K.; Deszcz, L.; Orban-Nemeth, Z.; Sakamoto, S.; Mechtler, K.; Kukura, P.; Clausen, T.; Haselbach, D.; Ikeda, F.
10.1101/2020.05.27.117952 — biochemistry — Posted on 2020-06-10
3465 A complex resistance locus in Solanum americanum recognizes a conserved Phytophthora effector
Witek, K.; Lin, X.; Karki, H. S.; Jupe, F.; Witek, A. I.; Steuernagel, B.; Stam, R.; Van Oosterhout, C.; Fairhead, S.; Cocker, J. M.; Bhanvadia, S.; Barrett, W.; Wu, C.-h.; Adachi, H.; Song, T.; Kamoun, S.; Vleeshouwers, V. G.; Tomlinson, L.; Wulff, B. B.; Jones, J. D.
10.1101/2020.05.15.095497 — plant biology — Posted on 2020-06-10
3470 Cholesterol sensing by CD81 is important for hepatitis C virus entry
Palor, M.; Stejskal, L.; Mandal, P.; Lenman, A.; Alberione, P. M.; Kiruine, J.; Moeller, R.; Ebner, S.; Meissner, F.; Gerold, G.; Shepherd, A. J.; Grove, J.
10.1101/542837 — molecular biology — Posted on 2020-06-10
3471 Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies
Hardenberg, M. C.; Sinnige, T.; Casford, S.; Dada, S.; Poudel, C.; Robinson, L.; Fuxreiter, M.; Kaminski, C. F.; Kaminski Schierle, G. S.; Nollen, E. A. A.; Dobson, C. M.; Vendruscolo, M.
10.1101/2020.06.08.140798 — molecular biology — Posted on 2020-06-10
3473 Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike
Prevost, J.; Gasser, R.; Beaudoin-Bussieres, G.; Richard, J.; Duerr, R.; Laumaea, A.; Anand, S. P.; Goyette, G.; Ding, S.; Medjahed, H.; Lewin, A.; Perreault, J.; Tremblay, T.; Gendron-Lepage, G.; Gauthier, N.; Carrier, M.; Marcoux, D.; Piche, A.; Lavoie, M.; Benoit, A.; Loungnarath, V.; Brochu, G.; Desforges, M.; Talbot, P. J.; Gould Maule, G. T.; Cote, M.; Therrien, C.; Serhir, B.; Bazin, R.; Roger, M.; Finzi, A.
10.1101/2020.06.08.140244 — microbiology — Posted on 2020-06-10
3474 Disentangling principled and opportunistic motives for reacting to injustice: A genetically-informed exploration of justice sensitivity
Eftedal, N. H.; Kleppesto, T. H.; Czajkowski, N. O.; Sheehy-Skeffington, J.; Roysamb, E.; Vassend, O.; Ystrom, E.; Thomsen, L.
10.1101/2020.06.10.143925 — genetics — Posted on 2020-06-10
3478 MetaPrism: A Toolkit for Joint Taxa/Gene Analysis of Metagenomic Sequencing Data
Kim, J.; Jiang, S.; Xiao, G.; Xie, Y.; Liu, D.; Li, Q.; Koh, A. Y.; Zhan, X.
10.1101/664748 — bioinformatics — Posted on 2020-06-10
3480 Protein context shapes the specificity of domain-peptide interactions in vivo
Dionne, U.; Bourgault, E.; Dube, A. K.; Bradley, D.; Chartier, F.; Dandage, R.; Dibyachintan, S.; Despres, P. C.; Gish, G. D.; Lambert, J.-P.; Bisson, N.; Landry, C. R.
10.1101/2020.05.18.103002 — systems biology — Posted on 2020-06-10
3482 Non-Invasive Single-Cell Morphometry in Living Bacterial Biofilms
Zhang, M.; Zhang, J.; Wang, Y.; Wang, J.; Achimovich, A. M.; Acton, S. T.; Gahlmann, A.
10.1101/2020.05.28.120279 — microbiology — Posted on 2020-06-10
3484 Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutralization
Li, D.; Li, T.; Cai, H.; Yao, H.; Zhou, B.; Zhao, Y.; Qin, W.; Hutter, C. A. J.; Lai, Y.; Bao, J.; Lan, J.; Wong, G.; Seeger, M.; Lavillette, D.
10.1101/2020.06.09.143438 — biochemistry — Posted on 2020-06-10
3485 In vivo Interictal Neuronal Signatures of Human Periventricular Nodular Heterotopia
Frazzini, V.; Whitmarsh, S.; Lehongre, K.; Yger, P.; Lemarechal, J.-D.; Mathon, B.; Adam, C.; Hasboun, D.; Lambrecq, V.; Navarro, V.
10.1101/816173 — pathology — Posted on 2020-06-10
3486 Aβ oligomers induce sex-selective differences in mGluR5 pharmacology and pathophysiological signaling in Alzheimer mice
Abd-Elrahman, K. S.; Albaker, A.; de Souza, J. M.; Ribeiro, F. M.; Schlossmacher, M. G.; Tiberi, M.; Hamilton, A.; Ferguson, S. S. G.
10.1101/803262 — neuroscience — Posted on 2020-06-10
3487 Helicobacter pylori diversification during chronic infection within a single host generates sub-populations with distinct phenotypes
Jackson, L. K.; Potter, B.; Schneider, S. E.; Fitzgibbon, M.; Blair, K.; Farah, H.; Krishna, U.; Peek, R.; Bedford, T.; Salama, N. R.
10.1101/2020.06.10.144071 — microbiology — Posted on 2020-06-10
3489 Niche-selective inhibition of pathogenic Th17 cells by targeting metabolic redundancy
Wu, L.; Hollinshead, K. E. R.; Hao, Y.; Au, C.; Kroehling, L.; Ng, C.; Lin, W.-y.; Li, D.; Silva, H. M.; Shin, J.; Lafaille, J. J.; Possemato, R.; Pacold, M. E.; Papagiannakopoulos, T. Y.; Kimmelman, A. C.; Satija, R.; Littman, D. R.
10.1101/857961 — immunology — Posted on 2020-06-10
3490 Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation During a Pandemic
Pillay, S.; Giandhari, J.; Tegally, H.; Wilkinson, E.; Chimukangara, B.; Lessells, R.; Mattison, S.; Moosa, Y.; Gazy, I.; Fish, M.; Singh, L.; Khanyile, K. S.; Fonseca, V.; Giovanetti, M.; Alcantara, L. C. J.; de Oliveira, T.
10.1101/2020.06.10.144212 — genomics — Posted on 2020-06-10
3491 A Rare Deletion in SARS-CoV-2 ORF6 Dramatically Alters the Predicted Three-Dimensional Structure of the Resultant Protein
Riojas, M. A.; Frank, A. M.; Puthuveetil, N. P.; Flores, B.; Parker, M.; King, S. P.; Peiris, M.; Chu, D. K. W.; Benton, B.; Bradford, R.; Hazbon, M. H.; Rashid, S.
10.1101/2020.06.09.134460 — genomics — Posted on 2020-06-10
3492 Recombination and purifying selection preserves covariant movements of mosaic SARS-CoV-2 protein S
Tagliamonte, M. S.; Adid, N.; Ostrov, D. A.; Chillemi, G.; Kosakovsky Pond, S. L.; Salemi, M.; Mavian, C. N.
10.1101/2020.03.30.015685 — evolutionary biology — Posted on 2020-06-10
3493 Structure-Based Function Prediction using Graph Convolutional Networks
Gligorijevic, V.; Renfrew, P. D.; Kosciolek, T.; Leman, J. K.; Berenberg, D.; Vatanen, T.; Chandler, C.; Taylor, B. C.; Fisk, I. M.; Vlamakis, H.; Xavier, R. J.; Knight, R.; Cho, K.; Bonneau, R. A.
10.1101/786236 — bioinformatics — Posted on 2020-06-10
3495 Plasma Membrane Phylloquinone Biosynthesis in Nonphotosynthetic Parasitic Plants
Gu, X.; Chen, I.-G.; Harding, S.; Nyamdari, B.; Ortega, M. A.; Clermont, K.; Westwood, J.; Tsai, C.-J.
10.1101/257519 — plant biology — Posted on 2020-06-10
3496 Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy
Caldas, L. A.; Carneiro, F. A.; Higa, L. M.; Monteiro, F. L.; da Silva, G. P.; Costa, L. J. d.; Durigon, E. L.; Tanuri, A.; de Souza, W.
10.1101/2020.06.10.144642 — microbiology — Posted on 2020-06-10
3497 Age-dependent progression of SARS-CoV-2 infection in Syrian hamsters
Osterrieder, N.; Bertzbach, L. D.; Dietert, K.; Abdelgawad, A.; Vladimirova, D.; Kunec, D.; Hoffmann, D.; Beer, M.; Gruber, A. D.; Trimpert, J.
10.1101/2020.06.10.144188 — microbiology — Posted on 2020-06-10
3499 Fast isolation of sub-nanomolar affinity alpaca nanobody against the Spike RBD of SARS-CoV-2 by combining bacterial display and a simple single-step density gradient selection
Valenzuela Nieto, G. E.; Jara, R.; Himelreichs, J.; Salinas, C.; Pinto, T.; Cheuquemilla, Y.; Margolles, Y.; Lopez Gonzalez del Rey, N.; Miranda Chacon, Z.; Cuevas, A.; Berking, A.; Deride, C.; Gonzalez-Moraga, S.; Mancilla, H.; Maturana, D.; Langer, A.; Toledo, J. P.; Müller, A.; Uberti, B.; Krall, P.; Ehrenfeld, P.; Blesa, J.; Chana-Cuevas, P.; Rehren, G.; Fernandez, L. A.; Rojas-Fernandez, A.
10.1101/2020.06.09.137935 — molecular biology — Posted on 2020-06-10
3501 Evaluating the efficacy of RT-qPCR SARS-CoV-2 direct approaches in comparison to RNA extraction
Israeli, O.; Beth-Din, A.; Paran, N.; Stein, D.; Lazar, S.; Weiss, S.; Milrot, E.; Atiya-Nasagi, Y.; Yitzhaki, S.; Laskar, O.; Schuster, O.
10.1101/2020.06.10.144196 — microbiology — Posted on 2020-06-10
3503 Direct energy transfer from photosystem II to photosystem I is the major regulator of winter sustainability of Scots pine
Bag, P.; Chukhutsina, V.; Zhang, Z.; Paul, S.; Ivanov, A. G.; Shutova, T.; Croce, R.; Holzwarth, A. R.; Jansson, S.
10.1101/2020.06.10.144170 — plant biology — Posted on 2020-06-10
3504 Visualizing ATP Dynamics in Live Mice
Koitabashi, N.; Ogasawara, R.; Yasui, R.; Sugiura, Y.; Matsuda, H.; Nonaka, S.; Izumi, T.; Kurabayashi, M.; Suematsu, M.; Yanagita, M.; Imamura, H.; Yamamoto, M.
10.1101/2020.06.10.143560 — physiology — Posted on 2020-06-10
3507 Pooling size sorted malaise trap fractions to maximise taxon recovery with metabarcoding
Elbrecht, V.; Bourlat, S. J.; Hoerren, T.; Lindner, A.; Mordente, A.; Noll, N. W.; Sorg, M.; Zizka, V. M. A.
10.1101/2020.06.09.118950 — molecular biology — Posted on 2020-06-10
3508 Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle
Conceicao, M.; Forcina, L.; Wiklander, O. P. B.; Gupta, D.; Nordin, J. Z.; McClorey, G.; Mager, I.; Gorgens, A.; Lundin, P.; Musaro, A.; Wood, M.; EL Andaloussi, S.; Roberts, T. C.
10.1101/2020.06.09.142216 — molecular biology — Posted on 2020-06-10
3509 The Potential of Capsicum annum Extracts to Prevent Lactococcosis in Tilapia
Ndashe, K.; Nghake, S.; Pola, E.; Sakala, E. M.; Kabwali, E.; Moonga, L.; Kefi, A. S.; Hangombe, B. M.
10.1101/2020.06.09.142406 — microbiology — Posted on 2020-06-10
3510 Bacterial protein domains with a novel Ig-like fold bind human CEACAM receptors
van Sorge, N. M.; Bonsor, D. A.; Deng, L.; Lindahl, E.; Schmitt, V.; Lyndin, M.; Schmidt, A.; Nilsson, O. R.; Brizuela, J.; Boero, E.; Sundberg, E. J.; van Strijp, J.; Doran, K. S.; Singer, B. S.; Lindahl, G.; McCarthy, A. J.
10.1101/2020.06.09.141622 — microbiology — Posted on 2020-06-10
3511 Extensive transfer of genes for edible seaweed digestion from marine to human gut bacteria
Pudlo, N. A.; Vasconcelos Pereira, G.; Parnami, J.; Cid, M.; Markert, S.; Tingley, J. P.; Unfried, F.; Ali, A.; Campbell, A.; Urs, K.; Xiao, Y.; Adams, R.; Martin, D.; Bolam, D. N.; Becher, D.; Schmidt, T. M.; Abbott, W.; Schweder, T.; Hehemann, J. H.; Martens, E. C.
10.1101/2020.06.09.142968 — microbiology — Posted on 2020-06-10
3512 Epigenome-wide change and variation in DNA methylation from birth to late adolescence
Mulder, R. H.; Neumann, A. H.; Cecil, C. A.; Walton, E.; Houtepen, L. C.; Simpkin, A. J.; Rijlaarsdam, J.; Heijmans, B. T.; Gaunt, T. R.; Felix, J. F.; Jaddoe, V. W.; Bakermans-Kranenburg, M. J.; Tiemeier, H.; Relton, C. L.; van IJzendoorn, M. H.; Suderman, M.
10.1101/2020.06.09.142620 — genomics — Posted on 2020-06-10
3514 SPECIFIC ECTODERMAL ENHANCERS CONTROL THE EXPRESSION OF HoxC GENES IN DEVELOPING MAMMALIAN INTEGUMENTS
Fernandez-Guerrero, M.; Yakushiji-Kaminatsui, N.; Lopez-Delisle, L.; Zdral, S.; Darbellay, F.; Perez-Gomez, R.; Bolt, C. C.; Sanchez-Martin, M. A.; Duboule, D.; Ros, M. A.
10.1101/2020.06.10.143677 — developmental biology — Posted on 2020-06-10
3515 Understanding the role of apolipoprotein A-I in atherosclerosis. Post-translational modifications synergize dysfunction?
Diaz Ludovico, I.; Gisonno, R. A.; Ramella, N. A.; Tricerri, M. A.; Tricerri, M. A.; Tricerri, M. A.
10.1101/2020.06.09.142844 — biophysics — Posted on 2020-06-10
3517 Prime editing for functional repair in patient-derived disease models
Schene, I. F.; Joore, I. P.; Mokry, M.; van Vugt, A. H. M.; van Hasselt, P. M.; Nieuwenhuis, E. E. S.; Fuchs, S. A.
10.1101/2020.06.09.139782 — genomics — Posted on 2020-06-10
3522 Differential activity and expression of human 5β-reductase (AKR1D1) splice variants
Appanna, N.; Gangitano, E.; Dempster, N. J.; Morris, K.; George, S.; Keevil, B. G.; Penning, T. M.; Gathercole, L. L.; Tomlinson, J. W.; Nikolaou, N.
10.1101/2020.06.09.142539 — molecular biology — Posted on 2020-06-10
3525 Phylogenetic Analysis of St. Louis Encephalitis Virus within Two Southwestern United State Counties: a case for a bulk introduction event into the southwest United States
Ridenour, C. L.; Cocking, J.; Poidmore, S.; Erickson, D.; Brock, B.; Valentine, M.; Young, S. J.; Henke, J. A.; Hung, K. Y.; Wittie, J.; Hornstra O'Neill, H. M.; Sheridan, K.; Centner, H.; Lemmer, D.; Fofanov, V.; Smith, K.; Will, J.; Townsend, J.; Keim, P. S.; Engelthaler, D. M.; Hepp, C. M.
10.1101/2020.06.10.143818 — bioinformatics — Posted on 2020-06-10
3527 Activity-specificity trade-off gives PI5P4Kβ a nucleotide preference to function as a GTP-sensing kinase.
Takeuchi, K.; Ikeda, Y.; Senda, M.; Harada, A.; Okuwaki, K.; Fukuzawa, K.; Nakagawa, S.; Yu, H.; Nagase, L.; Imai, M.; Sasaki, M.; Lo, Y.; Sasaki, A. T.; Senda, T.
10.1101/2020.06.09.137430 — biochemistry — Posted on 2020-06-10
3529 Beyond sharing unpleasant affect - evidence for pain-specific opioidergic modulation of empathy for pain
Rütgen, M.; Wirth, E.-M.; Riecansky, I.; Hummer, A.; Windischberger, C.; Petrovic, P.; Silani, G.; Lamm, C.
10.1101/2020.06.10.143495 — neuroscience — Posted on 2020-06-10
3533 Urokinase receptor associates with TLR4 interactome to promote LPS response
Kiyan, Y.; Tkachuk, S.; Gorrasi, A.; Ragno, P.; Dumler, I.; Haller, H.; Shushakova, N.
10.1101/2020.06.10.143826 — cell biology — Posted on 2020-06-10
3534 Light-activated signaling in DNA-encoded sender-receiver architectures
Yang, S.; Pieters, P.; Joesaar, A.; Bogels, B.; Brouwers, R.; Myrgorodska, I.; Mann, S.; de Greef, T.
10.1101/2020.06.10.144162 — synthetic biology — Posted on 2020-06-10
3535 Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history
Coscolla Devis, M.; Brites, D.; Menardo, F.; Loiseau, C. M.; Borrell Farnov, s.; Otchere, I. D.; Asante-Poku, A.; Sanchez-Buso, L.; Gehre, F.; Sanoussi, C. N. D.; Antonio, M.; Dissou, A.; Ruiz-Rodriguez, P.; Fyfe, J.; Meehan, C. J.; Becket, P.; Niemann, S.; Alabi, A. S.; Grobusch, M. P.; Kobbe, R.; Asare, P.; Parkhill, J.; Beisel, C.; Fenner, L.; Bottger, E. C.; Harris, S. R.; C. de Jong, B.; Yeboah-Manu, D.; Gagneux, S.
10.1101/2020.06.10.141788 — genomics — Posted on 2020-06-10
3536 Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans
Fatumo, S.; Chikowore, T.; Kalyesubula, R.; Nsubuga, R. N.; Asiki, G.; Nashiru, O.; Seeley, J.; Crampin, A. C.; Nitsch, D.; Smeeth, L.; Kaleebu, P.; Nyirenda, M.; Burgess, S.; Franceschini, N.; Morris, A. P.; Tomlinson, L.; Newton, R.
10.1101/2020.06.09.142463 — genetics — Posted on 2020-06-10
3537 Ancient bacterial genomes reveal a formerly unknown diversity of Treponema pallidum strains in early modern Europe
Majander, K.; Pfrengle, S.; Neukamm, J.; Kocher, A.; du Plessis, L.; Pla-Diaz, M.; Arora, N.; Akgül, G.; Salo, K.; Schats, R.; Inskip, S.; Oinonen, M.; Valk, H.; Malve, M.; Kriiska, A.; Onkamo, P.; Gonzalez-Candelas, F.; Kühnert, D.; Krause, J.; Schuenemann, V.
10.1101/2020.06.09.142547 — genetics — Posted on 2020-06-10
3540 p53-dependent polyploidisation after DNA damage in G2 phase
Middleton, A. W.; Suman, R.; O'Toole, P.; Akopyan, K.; Lindqvist, A.
10.1101/2020.06.09.141770 — cell biology — Posted on 2020-06-10
3541 A Phelipanche ramosa KAI2 Protein Perceives enzymatically Strigolactones and Isothiocyanates
de Saint Germain, A.; JACOBS, A.; Brun, G.; Pouvreau, J.-B.; Braem, L.; Cornu, D.; Clave, G.; Baudu, E.; Steinmetz, V.; Servajean, V.; Wicke, S.; Gevaert, K.; Simier, P.; Goormachtig, S.; Delavault, P.; Boyer, F.-D.
10.1101/2020.06.09.136473 — plant biology — Posted on 2020-06-10
3544 Signalome-wide assessment of erythrocyte response to Plasmodium reveals novel targets for host-directed antimalarial intervention
Adderley, J.; John non Freyend, S.; Jackson, S.; Bird, M.; Burns, A.; Anar, B.; Metcalf, T.; Semblat, J.-P.; Billker, O.; Wilson, D.; Doerig, C.
10.1101/2020.06.09.143206 — microbiology — Posted on 2020-06-10
3548 Histone deacetylase inhibition by gut microbe-generated short chain fatty acids entrains intestinal epithelial circadian rhythms
Luzader, D. H.; Fawad, J. A.; Moutinho, T. J.; Mitchell, P. G.; Brown-Steinke, K.; Zhao, J. Y.; Rosselot, A. E.; McKinney, C. A.; Hong, C. I.; Chou, C. J.; Papin, J. A.; Moore, S. R.
10.1101/2020.06.09.143057 — cell biology — Posted on 2020-06-10
3552 Genomic and kinetic analysis of novel Nitrospinae enriched by cell sorting
Mueller, A. J.; Jung, M.-Y.; Strachan, C. R.; Herbold, C. W.; Kirkegaard, R. H.; Wagner, M.; Daims, H.
10.1101/2020.06.09.141952 — microbiology — Posted on 2020-06-10
3554 Endochondral bone in an Early Devonian 'placoderm' from Mongolia
Brazeau, M.; Giles, S.; Dearden, R.; Jerve, A.; Ariunchimeg, Y.; Zorig, E.; Guillerme, T.; Castiello, M.
10.1101/2020.06.09.132027 — paleontology — Posted on 2020-06-10
3557 Syndecan-4-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components
Roenning, S. B.; Carlson, C.; Aronsen, J. M.; Pisconti, A.; Hoest, V.; Lunde, M.; Liland, K. H.; Sjaastad, I.; Kolset, S.-O.; Pedersen, M. E.
10.1101/2020.06.10.143982 — cell biology — Posted on 2020-06-10
3558 Multi-Dimensional Immuno-Profiling of Drosophila Hemocytes by Single Cell Mass Cytometry
Balog, J. A.; Honti, V.; Kurucz, E.; Kari, B.; Puskas, L. G.; Ando, I.; Szebeni, G. J.
10.1101/2020.06.10.144584 — immunology — Posted on 2020-06-10
3560 Single Cell-type Integrative Network Modeling IdentifiedNovel Microglial-specific Targets for the Phagosome inAlzheimer's disease
Patel, K. R.; Zhu, K.; Henrion, M. Y.; Beckmann, N.; Moein, S.; Alamprese, M. L.; Allen, M.; Wang, X.; Chen, G.; Pertel, T.; Nejad, P.; Reddy, J. S.; Carrasquillo, M. M.; Bennett, D. A.; Ertekin-Taner, N.; Jager, P. D.; Schadt, E.; Bradshaw, E. M.; Chang, R.
10.1101/2020.06.09.143529 — systems biology — Posted on 2020-06-10
3561 Synaptic accumulation of FUS triggers age-dependent misregulation of inhibitory synapses in ALS-FUS mice
Sahadevan, S.; Hembach, K. M.; Tantardini, E.; Perez-Berlanga, M.; Hruska-Plochan, M.; Weber, J.; Schwarz, P.; Dupuis, L.; Robinson, M. D.; De Rossi, P.; Polymenidou, M.
10.1101/2020.06.10.136010 — neuroscience — Posted on 2020-06-10
3562 A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance
Al-Akhrass, H.; Conway, J. R. W.; Poulsen, A. S. A.; Paatero, I.; Kaivola, J.; Padzik, A.; Andersen, O. M.; Ivaska, J.
10.1101/2020.06.10.143735 — cancer biology — Posted on 2020-06-10
3563 Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system
Cantuti-Castelvetri, L.; Ohja, R.; Pedro, L.; Djannatian, M.; Franz, J.; Kuivanen, S.; Kallio, K.; Kaya, T.; Anastasina, M.; Smura, T.; Levanov, L.; Szirovicza, L.; Tobi, A.; Kallio-Kokko, H.; Osterlund, P.; Joensuu, M.; Meunier, F.; Butcher, S.; Winkler, M.; Mollenhauer, B.; Helenius, A.; Gokce, O.; Teesalu, T.; Hepojoki, J.; Vapalahti, O.; Stadelmann, C.; Balistreri, G.; Simons, M.
10.1101/2020.06.07.137802 — microbiology — Posted on 2020-06-10
3569 Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and regulate behavioral odor discrimination
Wong, J. Y. H.; Wan, B. A.; McLachlan, A. D.; Montagnese, M.; O'Kane, C. J.; Bland, T.; Zhang, S. W.; Masuda-Nakagawa, L. M.
10.1101/295659 — neuroscience — Posted on 2020-06-10
3575 Microbiota-derived short chain fatty acids promote Aβ plaque deposition
Colombo, A. V.; Sadler, R. K.; Llovera, G.; Singh, V.; Roth, S.; Heindl, S.; Sebastian Monasor, L.; Verhoeven, A.; Peters, F.; Parhizkar, S.; Kamp, F.; Gomez de Aguero, M.; Macpherson, A.; Winkler, E.; Herms, J.; Benakis, C.; Dichgans, M.; Steiner, H.; Giera, M.; Haass, C.; Tahirovic, S.; Liesz, A.
10.1101/2020.06.09.141879 — neuroscience — Posted on 2020-06-10
3577 Quantitative data independent acquisition glycoproteomics of sparkling wine
Pegg, C. L.; Phung, T. K.; Caboche, C. H.; Niamsuphap, S.; Bern, M.; Howell, K.; Schulz, B. L.
10.1101/2020.06.09.141226 — biochemistry — Posted on 2020-06-10
3578 The mRNA translation landscape in the synaptic neuropil.
Glock, C.; Biever, A.; Tushev, G.; Bartnik, I.; Nassim-Assir, B.; Tom Dieck, S.; Schuman, E. M.
10.1101/2020.06.09.141960 — neuroscience — Posted on 2020-06-10
3579 Dual RNase and β-lactamase activity of a single enzyme encoded in most Archaea
Diene, S. M.; Pinault, L.; Armstrong, N.; Keshri, V.; Khelaifia, S.; Chabriere, E.; Caetano-Anolles, G.; Rolain, J.-M.; Pontarotti, P.; Raoult, D.
10.1101/667907 — microbiology — Posted on 2020-06-10
3580 GABAA receptor mapping in human using non-invasive electrophysiology.
Shaw, A. D.; Chandler, H. L.; Hamandi, K.; Muthukumaraswamy, S. D.; Hammers, A.; Singh, K. D.
10.1101/2020.05.11.087726 — neuroscience — Posted on 2020-06-10
3581 On the objectivity, reliability, and validity of deep learning enabled bioimage analyses
Segebarth, D.; Griebel, M.; Stein, N.; R. von Collenberg, C.; Martin, C.; Fiedler, D.; Comeras, L. B.; Sah, A.; Schoeffler, V.; Lueffe, T.; Duerr, A.; Gupta, R.; Sasi, M.; Lillesaar, C.; Lange, M. D.; Tasan, R. O.; Singewald, N.; Pape, H.-C.; Flath, C. M.; Blum, R.
10.1101/473199 — neuroscience — Posted on 2020-06-10
3582 Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey
Adebali, O.; Bircan, A.; Circi, D.; Islek, B.; Kilinc, Z.; Selcuk, B.; Turhan, B.
10.1101/2020.05.15.095794 — genomics — Posted on 2020-06-10
3583 Compensatory hippocampal neurogenesis in the absence of cognitive impairment following experimental hippocampectomy in adult rats
Cardoso, G. T.; Gomes-Leal, W.; Franco, E. C.; Gama, J. S.; Gomes, F. L.; Pereira, A.; Brino, A. L. F.; Lima, S. M. A.
10.1101/2020.06.04.135350 — neuroscience — Posted on 2020-06-10
3585

The low-density lipoprotein receptor-related protein-1 is essential for Dengue virus infection

Huerta Galindo, V.; Martin, A. M.; Sarria, M.; Guirola, O.; Yero, A.; Ramos, Y.; Pupo, D.; Martin, D.; Marcello, A.; Chinea, G.
10.1101/2020.06.10.144089 — biochemistry — Posted on 2020-06-10
3586 Inference and validation of an integrated regulatory network of autism
Ganji, M.; Emadi-Baygi, M.; Mohammadtaheri, F.; Mirmohammadsadeghi, N.; Malek, M.; Waltemath, D.; Salehzadeh-Yazdi, A.; Nikpour, P.
10.1101/2020.06.08.139733 — systems biology — Posted on 2020-06-10
3587 Anxiety and the neurobiology of temporally uncertain threat anticipation
Hur, J.; Smith, J. F.; DeYoung, K. A.; Anderson, A. S.; Kuang, J.; Kim, H. C.; Tillman, R. M.; Kuhn, M.; Fox, A. S.; Shackman, A. J.
10.1101/2020.02.25.964734 — neuroscience — Posted on 2020-06-10
3588 Transgenic goats producing an improved version of cetuximab in milk
Laible, G.; Cole, S.; Brophy, B.; Maclean, P.; Chen, L. H.; Pollock, D. P.; Cavacini, L.; Fournier, N.; De Romeuf, C.; Masiello, N. C.; Gavin, W. G.; Wells, D. N.; Meade, H. M.
10.1101/2020.06.05.137463 — molecular biology — Posted on 2020-06-10
3590 Myosin-X FERM domain modulates integrin activity at filopodia tips
Miihkinen, M.; Grönloh, M. L. B.; Vihinen, H.; Jokitalo, E.; Goult, B. T.; Ivaska, J.; Jacquemet, G.
10.1101/2020.05.05.078733 — cell biology — Posted on 2020-06-10
3591 Alternative polyadenylation is a determinant of oncogenic Ras function
Subramanian, A.; Hall, M.; Hou, H.; Mufteev, M.; Yu, B.; Yuki, K. E.; Nishimura, H.; Sathaseevan, A.; Lant, B.; Zhai, B.; Ellis, J.; Wilson, M. D.; Daugaard, M.; Derry, W. B.
10.1101/2020.06.08.140145 — cancer biology — Posted on 2020-06-10
3592 Functional and molecular early enteric biomarkers for Parkinson's disease in mice and men
Gries, M.; Christmann, A.; Schulte, S.; Weyland, M.; Rommel, S.; Martin, M.; Baller, M.; Roeth, R.; Schmitteckert, S.; Unger, M.; Liu, Y.; Sommer, F.; Muehlhaus, T.; Schroda, M.; Timmermans, J.-P.; Pintelon, I.; Rappold, G. A.; Britschgi, M.; Lashuel, H.; Menger, M. D.; Laschke, M. W.; Niesler, B.; Schaefer, K.-H.
10.1101/2020.06.06.136556 — neuroscience — Posted on 2020-06-10
3594 Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Lv, Z.; Deng, Y.-Q.; Ye, Q.; Cao, L.; Sun, C.-Y.; Fan, C.; Huang, W.; Sun, S.; Sun, Y.; Zhu, L.; Chen, Q.; Wang, N.; Nie, J.; Cui, Z.; Zhu, D.; Shaw, N.; Li, X.-F.; Li, Q.; Xie, L.; Wang, Y.; Rao, Z.; Qin, C.-F.; Wang, X.
10.1101/2020.06.02.129098 — biophysics — Posted on 2020-06-10
3597 ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics
Garcia-Castro, H.; Kenny, N. J.; Alvarez-Campos, P.; Mason, V.; Schönauer, A.; Sleight, V. A.; Neiro, J.; Aboobaker, A.; Permanyer, J.; Iglesias, M.; Irimia, M.; Sebe-Pedros, A.; Solana, J.
10.1101/2020.05.26.117234 — systems biology — Posted on 2020-06-10
3602 Lentiviral interleukin-10 gene therapy preserves fine motor circuitry and function after a cervical spinal cord injury in male and female mice
Chen, J. Y.; Fu, E. J.; Patel, P. R.; Sawan, H. A.; Moss, K. A.; Hostetler, A. J.; Hocevar, S. E.; Smith, D. R.; Anderson, A. J.; Chestek, C. A.; Shea, L. D.
10.1101/2020.06.05.137257 — neuroscience — Posted on 2020-06-10
3603 Functional reconstitution of a bacterial CO2 concentrating mechanism in E. coli
Flamholz, A. I.; Dugan, E.; Blikstad, C.; Gleizer, S.; Ben-Nissan, R.; Amram, S.; Antonovsky, N.; Ravishankar, S.; Noor, E.; Bar-Even, A.; Milo, R.; Savage, D.
10.1101/2020.05.27.119784 — microbiology — Posted on 2020-06-10
3605 Synthetic antibodies neutralize SARS-CoV-2 infection of mammalian cells
Miersch, S.; Ustav, M.; Li, Z.; Case, J. B.; Ganaie, S.; Matusali, G.; Colavita, F.; Lapa, D.; Capobianchi, M. R.; Novelli, G.; Gupta, J. B.; Jain, S.; Pandolfi, P. P.; Diamond, M. S.; Amarasinghe, G.; Rini, J. M.; Sidhu, S. S.
10.1101/2020.06.05.137349 — biochemistry — Posted on 2020-06-10
3606 Transcriptional profiling reveals TRPM5-expressing cells involved in viral infection in the olfactory epithelium
Baxter, B. D.; Larson, E. D.; Feinstein, P.; Polese, A. G.; Bubak, A. N.; Niemeyer, C. S.; Merle, L.; Shepherd, D.; Ramakrishnan, V. R.; Nagel, M. A.; Restrepo, D.
10.1101/2020.05.14.096016 — neuroscience — Posted on 2020-06-10
3607 The Caribbean-Hispanic Alzheimer's Brain Transcriptome Reveals Ancestry-Specific Disease Mechanisms
Felsky, D.; Sariya, S.; Santa-Maria, I.; French, L.; Schneider, J. A.; Bennett, D. A.; Mayeux, R. P.; De Jager, P. L.; Tosto, G.
10.1101/2020.05.28.122234 — genomics — Posted on 2020-06-10
3608 Mis-annotated multi nucleotide variants in public cancer genomics datasets can lead to inaccurate mutation calls with significant implications
Srinivasan, S.; Kalinava, N.; Aldana, R.; Li, Z.; Van Hagen, S.; Rodenburg, S. Y. A.; Wind-Rotolo, M.; Sasson, A. S.; Tang, H.; Qian, X.; Kirov, S.
10.1101/2020.06.05.136549 — genomics — Posted on 2020-06-10
3609 Chromatin and transcriptional response to loss of TBX1 in early differentiation of mouse cells.
Cirino, A.; Aurigemma, I.; Franzese, M.; Lania, G.; Righelli, D.; Ferrentino, R.; Illingworth, E.; Angelini, C.; Baldini, A.
10.1101/2020.06.06.137026 — developmental biology — Posted on 2020-06-10
3610 Spatial confinement and temporal dynamics of selectin ligands enable stable hematopoietic stem cell rolling
Al Alwan, B.; AbuZineh, K.; Nozue, S.; Rakhmatulina, A.; Aldehaiman, M.; Al-Amoodi, A. S.; Serag, M. F.; Aleisa, F. A.; Merzaban, J. S.; Habuchi, S.
10.1101/2020.04.29.069617 — biophysics — Posted on 2020-06-10
3615 Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates
Garcia-Huerta, P.; Troncoso-Escudero, P.; Wu, D.; Thiruvalluvan, A.; Cisternas, M.; Henriquez, D. R.; Plate, L.; Chana-Cuevas, P.; Sequel, C.; Thielen, P.; Longo, K. A.; Geddes, B. J.; Lederkremer, G.; Sharma, N.; Shenkman, M.; Naphade, S.; Sardi, P.; Spichiger, C.; Richter, H. G.; Court, F.; Tshilenge, K.-T.; Ellerby, L.; Wiseman, L.; Gonzalez-Billault, C.; Bergink, S.; Vidal, R. L.; Hetz, C.
10.1101/2020.05.28.119164 — neuroscience — Posted on 2020-06-10
3618 Burkholderia thailandensis methylated hydroxy-alkylquinolines: biosynthesis and antimicrobial activity in co-culture experiments
Klaus, J. R.; Majerczyk, C.; Moon, S.; Eppler, N. A.; Smith, S.; Tuma, E.; Groleau, M.-C.; Asfahl, K. L.; Smalley, N. E.; Hayden, H.; Piochon, M.; Ball, P.; Dandekar, A. A.; Gauthier, C.; Deziel, E.; Chandler, J. R.
10.1101/2020.05.27.120295 — microbiology — Posted on 2020-06-10
3619 Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014
Huong, N. Q.; Nga, N. T. T.; Long, N. V.; Luu, B. D.; Latinne, A.; Pruvot, M.; Phuong, N. T.; Quang, L. T. V.; Hung, V. V.; Lan, N. T.; Hoa, N. T.; Minh, P. Q.; Diep, N. T.; Tung, N.; Ky, V. D.; Roberton, S. I.; Thuy, H. B.; Long, N. V.; Gilbert, M.; Wicker, L.; Mazet, J. A. K.; Johnson, C. K.; Goldstein, T.; Tremeau-Bravard, A.; Ontiveros, V.; Joly, D. O.; Walzer, C.; Fine, A. E.; Olson, S. H.
10.1101/2020.06.05.098590 — microbiology — Posted on 2020-06-10
3621 Persistence of a Wolbachia-driven sex ratio bias in an island population of Eurema butterflies
Kageyama, D.; Narita, S.; Konagaya, T.; Miyata, M.; Abe, J.; Mitsuhashi, W.; Nomura, M.
10.1101/2020.03.24.005017 — evolutionary biology — Posted on 2020-06-10
3623 Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19
Mirabelli, C.; Wotring, J. W.; Zhang, C. J.; McCarty, S. M.; Fursmidt, R.; Frum, T.; Kadambi, N. S.; Amin, A. T.; O'Meara, T. R.; Pretto-Kernahan, C. D.; Spence, J. R.; Huang, J.; Alysandratos, K. D.; Kotton, D. N.; Handelman, S. K.; Wobus, C. E.; Weatherwax, K. J.; Mashour, G. A.; O'Meara, M. J.; Sexton, J. Z.
10.1101/2020.05.27.117184 — cell biology — Posted on 2020-06-10
3624 Rapid Generation of Protein Condensate Phase Diagrams Using Combinatorial Droplet Microfluidics
Arter, W. E.; Qi, R.; Krainer, G. E.; Welsh, T. J.; Xu, Y.; St George-Hyslop, P.; Alberti, S.; Knowles, T.
10.1101/2020.06.04.132308 — biophysics — Posted on 2020-06-10
3628 Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination
Kimanius, D.; Zickert, G.; Nakane, T.; Adler, J.; Lunz, S.; Schonlieb, C.-B.; Oktem, O.; Scheres, S.
10.1101/2020.03.25.007914 — molecular biology — Posted on 2020-06-10
3633 METTL5, an 18S rRNA-specific m6A methyltransferase, modulates expression of stress response genes
CHEN, H.; Liu, Q.; Yu, D.; Natchiar, K.; Zhou, C.; Hsu, C.-h.; Hsu, P.-H.; Zhang, X.; Klaholz, B.; Gregory, R.; Cheng, X.; Shi, Y.
10.1101/2020.04.27.064162 — biochemistry — Posted on 2020-06-10
3635 Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles.
Kanakis, I.; Alameddine, M.; Scalabrin, M.; van 't Hof, R. J.; Liloglou, T.; Ozanne, S. E.; Goljanek-Whysall, K.; Vasilaki, A.
10.1101/2020.05.02.073759 — physiology — Posted on 2020-06-10
3636 Reduced Auditory Steady State Responses in Autism Spectrum Disorder
Seymour, R. A.; Rippon, G.; Gooding-Williams, G.; Sowman, P. F.; Kessler, K.
10.1101/837633 — neuroscience — Posted on 2020-06-10
3638 R.ROSETTA: an interpretable machine learning framework
Garbulowski, M.; Diamanti, K.; Smolinska, K.; Baltzer, N.; Stoll, P.; Bornelov, S.; Ohrn, A.; Feuk, L.; Komorowski, J.
10.1101/625905 — bioinformatics — Posted on 2020-06-10
3641 Organization of cortico-hippocampal networks in the human brain
Barnett, A. J.; Reilly, W.; Dimsdale-Zucker, H.; Mizrak, E.; Reagh, Z.; Ranganath, C.
10.1101/2020.06.09.142166 — neuroscience — Posted on 2020-06-10
3642 When is a control not a control? Reactive microglia occur throughout the control contralateral visual pathway in experimental glaucoma
Tribble, J. R.; Kokkali, E.; Otmani, A.; Plastino, F.; Lardner, E.; Vohra, R.; Kolko, M.; Andre, H.; Morgan, J. E.; Williams, P. A.
10.1101/853275 — neuroscience — Posted on 2020-06-10
3643 Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis
Wright, A. L.; Della Gatta, P.; Le, S.; Berning, B. A.; Mehta, P.; Jacobs, K. R.; Gul, H.; San Gil, R.; Hedl, T. J.; Riddell, W. R.; Watson, O.; Keating, S. S.; Venturato, J.; Chung, R. S.; Atkin, J. D.; Lee, A.; Shi, B.; Blizzard, C. A.; Morsch, M.; Walker, A. K.
10.1101/749846 — neuroscience — Posted on 2020-06-10
3644 Patient-specific functional genomics and disease modeling suggest a role for LRP2 in Hypoplastic Left Heart Syndrome
Theis, J. L.; Vogler, G.; Missinato, M. A.; Li, X.; Martinez-Fernandez, A.; Nielsen, T.; Walls, S. M.; Kervadec, A.; Zeng, X.-X. I.; Kezos, J. N.; Birker, K.; Evans, J. M.; O'Byrne, M. M.; Fogarty, Z. C.; Terzic, A.; Grossfeld, P.; Ocorr, K.; Colas, A. R.; Nelson, T. J.; Olson, T. M.; Bodmer, R.
10.1101/835439 — genetics — Posted on 2020-06-10
3647 A model to study orienting responses in zebrafish, and applications towards the emotion-cognition interaction
do Nascimento, B. G.; Oliveira e Oliveira, H. S. T.; Silva, H. T. L.; de Siqueira-Silva, D. H.; Lima-Maximino, M. G.; Maximino, C.
10.1101/827733 — animal behavior and cognition — Posted on 2020-06-10
3648 In vivo Interictal Neuronal Signatures of Human Periventricular Nodular Heterotopia
Frazzini, V.; Whitmarsh, S.; Lambrecq, V.; Lehongre, K.; Yger, P.; Mathon, B.; Adam, C.; Hasboun, D.; Navarro, V.
10.1101/816173 — pathology — Posted on 2020-06-10
3649 Reproducibility across single-cell RNA-seq protocols for spatial ordering analysis
Seirup, M.; Chu, L.-F.; Sengupta, S.; Leng, N.; Browder, H.; Kapadia, K.; Shafer, C. M.; Duffin, B.; Elwell, A. L.; Bolin, J. M.; Swanson, S.; Stewart, R.; Kendziorski, C.; Thomson, J. A.; Bacher, R.
10.1101/764191 — genomics — Posted on 2020-06-10
3650 Phenylpropionc acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity
Cho, S.; Won, K.-J.; Yang, X.; Leone, V.; Chang, E. B.; Chung, E.; Park, J.-S.; Guzman, G.; Lee, H.; Jeong, H.
10.1101/811984 — pharmacology and toxicology — Posted on 2020-06-10
3651 Boosting Brain Signal Variability Underlies Liberal Shifts in Decision Bias
Kloosterman, N. A.; Kosciessa, J. Q.; Lindenberger, U.; Fahrenfort, J. J.; Garrett, D. D.
10.1101/834614 — neuroscience — Posted on 2020-06-09
3657 A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery
Choi, Y.-R.; Collins, K.; Springer, L.; Pferdehirt, L.; Ross, A.; Wu, C.-L.; Moutos, F.; Harasymowicz, N.; Brunger, J.; Pham, C.; Guilak, F.
10.1101/535609 — synthetic biology — Posted on 2020-06-09
3659 Gene expression correlates of social evolution in coral reef butterflyfishes
Nowicki, J.; Pratchett, M.; Coker, D.; Walker, S.; O'Connell, L. A.
10.1101/214759 — neuroscience — Posted on 2020-06-09
3661 Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
Li, W.; Hu, J.; Shi, B.; Digman, F.; Digman, M. A.; Gratton, E.; Jiang, H.
10.1101/536839 — biochemistry — Posted on 2020-06-09
3662 Stability of SARS-CoV-2 Phylogenies
Turakhia, Y.; Thornlow, B.; Gozashti, L.; Hinrichs, A.; Fernandes, J.; Haussler, D.; Corbett-Detig, R.
10.1101/2020.06.08.141127 — genomics — Posted on 2020-06-09
3664 Vascular Injury Changes Topology of Vessel Network to Adapt to Partition of Blood Flow for New Arteriovenous Specification
Baek, K. I.; Chang, S.-S.; Chang, C.-C.; Roustaei, M.; Ding, Y.; Wang, Y.; Chen, J.; Odonnelle, R.; Chen, H.; Ashby, J. W.; Mack, J. J.; Xu, X.; Cavallero, S.; Hsiai, T. K.
10.1101/2020.06.09.141408 — molecular biology — Posted on 2020-06-09
3665 Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteins
Shi, Y.; Shi, J.; Sun, L.; Tan, Y.; Wang, G.; Guo, F.; Hu, G.; Fu, Y.; Fu, Z. F.; Xiao, S.; Peng, G.
10.1101/2020.06.09.141580 — microbiology — Posted on 2020-06-09
3666 Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
Ding, S.; Zang, R.; Case, J. B.; Gomez Castro, M. F.; Liu, Z.; Zeng, Q.; Zhao, H.; Son, J.; Rothlauf, P. W.; Hou, G.; Bose, S.; Wang, X.; Vahey, M. D.; Kirchhausen, T.; Fremont, D. H.; Diamond, M. S.; Whelan, S. P. J.
10.1101/2020.06.08.141077 — microbiology — Posted on 2020-06-09
3668 Structural basis of a public antibody response to SARS-CoV-2
Yuan, M.; Liu, H.; Wu, N. C.; Lee, C.-C. D.; Zhu, X.; Zhao, F.; Huang, D.; Yu, W.; Hua, Y.; Tien, H.; Rogers, T. F.; Landais, E.; Sok, D.; Jardine, J. G.; Burton, D. R.; Wilson, I. A.
10.1101/2020.06.08.141267 — microbiology — Posted on 2020-06-09
3671 RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis.
Hernandez Sanchez-Rebato, M.; Bouatta, A. M.; Gallego, M. E.; White, C. I.; Da Ines, O.
10.1101/2020.06.09.142000 — genetics — Posted on 2020-06-09
3672 Comparison of CRISPR/Cas endonucleases for in vivo retinal gene editing.
Li, F.; Wing, K.; Wang, J.-H.; Luu, C. D.; Bender, J. A.; Chen, J.; Wang, Q.; Lu, Q.; Tran, M. T. N. T.; Young, K. M.; Wong, R. C.; Pebay, A.; Cook, A. L.; Hung, S. S.; Liu, G.-S.; Hewitt, A. W.
10.1101/2020.06.09.141705 — bioengineering — Posted on 2020-06-09
3679 The hypothalamus as a hub for putative SARS-CoV-2 brain infection
Nampoothiri, S.; Sauve, F.; Ternier, G.; Fernandois, D.; Coelho, C.; Imbernon, M.; Deligia, E.; Perbet, R.; Florent, V.; Baroncini, M.; Pasquier, F.; Trottein, F.; Maurage, C.-A.; Mattot, V.; Giacobini, P.; Rasika, S.; Prevot, V.
10.1101/2020.06.08.139329 — neuroscience — Posted on 2020-06-09
3680 The Profiling of Bisecting N-acetylglucosamine (GlcNAc) Modification in Human Amniotic Membrane by Glycomic and Glycoproteomic Analyses
Chen, Q.; zhang, y.; Zhang, K.; Liu, J.; Pan, H.; Wang, X.; Li, S.; Hu, D.; Lin, Z.; Zhao, Y.; Hou, G.; Guan, F.; Li, H.; Liu, S.; Ren, Y.
10.1101/2020.06.09.141168 — cell biology — Posted on 2020-06-09
3681 Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses
Schmidt, F.; Weisblum, Y.; Muecksch, F.; Hoffmann, H.-H.; Michailidis, E.; Lorenzi, J. C. C.; Mendoza, P.; Rutkowska, M.; Bednarski, E.; Gaebler, C.; Agudelo, M.; Cho, A.; Wang, Z.; Gazumyan, A.; Cipolla, M.; Caskey, M.; Robbiani, D. F.; Nussenzweig, M. C.; Rice, C. M.; Hatziioannou, T.; Bieniasz, P. D.
10.1101/2020.06.08.140871 — microbiology — Posted on 2020-06-09
3682 Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma
Salazar, E.; Kuchipudi, S. V.; Christensen, P. A.; Eagar, T. N.; Yi, X.; Zhao, P.; Jin, Z.; Long, S. W.; Olsen, R. J.; Chen, J.; Castillo, B.; Leveque, C.; Towers, D. M.; Lavinder, J.; Gollihar, J. D.; Cardona, J.; Ippolito, G. C.; Nissly, R. H.; Bird, I. M.; Greenawalt, D.; Rossi, R. M.; Gontu, A.; Srinivasan, S.; Poojary, I. B.; Cattadori, I. M.; Hudson, P. J.; Joselyn, N.; Prugar, L.; Huie, K.; Herbert, A.; Bernard, D. W.; Dye, J.; Kapur, V.; Musser, J. M.
10.1101/2020.06.08.138990 — immunology — Posted on 2020-06-09
3683 Characterization of the exopolysaccharide biosynthesis pathway in Myxococcus xanthus
Perez-Burgos, M.; Garcia-Romero, I.; Jung, J.; Schander, E.; Valvano, M. A.; Sogaard-Andersen, L.
10.1101/2020.06.08.139634 — microbiology — Posted on 2020-06-09
3684 Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially-infected epithelial cells
Bastounis, E. E.; Alcade, F. S.; Radhakrishnan, P.; Engstrom, P.; Gomez Benito, M. J.; Oswald, M. S.; Smith, J. G.; Welch, M.; Garcia-Aznar, J. M.; Theriot, J. A.
10.1101/2020.01.22.915140 — microbiology — Posted on 2020-06-09
3686 Genomic novelty versus convergence in the basis of adaptation to whole genome duplication
Bohutinska, M.; Alston, M.; Monnahan, P.; Mandakov, T.; Bray, S.; Paajanen, P.; Kolar, F.; Yant, L.
10.1101/2020.01.31.929109 — evolutionary biology — Posted on 2020-06-09
3687 Brain Tumor IDH, 1p/19q, and MGMT Molecular Classification Using MRI-based Deep Learning: Effect of Motion and Motion Correction
Nalawade, S.; Yu, F. F.; Bangalore Yogananda, C. G.; Murugesan, G. K.; Shah, B. R.; Pinho, M. C.; Wagner, B. C.; Mickey, B.; Patel, T. R.; Fei, B.; Madhuranthakam, A. J.; Maldjian, J. A.
10.1101/2020.06.01.126375 — neuroscience — Posted on 2020-06-09
3688 F5N : Nanopore Sequence Analysis Toolkit for Android Smartphones
Samarakoon, H.; Punchihewa, S.; Senanayake, A.; Ragel, R.; Gamaarachchi, H.
10.1101/2020.03.22.002030 — bioinformatics — Posted on 2020-06-09
3692 Primary platinum resistance and immune exclusion in ovarian carcinomas with high expression of the homologous recombination mediator RAD51
Hoppe, M. M.; Tan, T. Z.; Lie, S.; Lim, S.; Yeong, J. P.; Wardyn, J. D.; Jaynes, P.; Lim, D. G.; Pang, B. N.; Karnezis, A.; Chiu, D.; Leung, S.; Huntsman, D. G.; Sedukhina, A. S.; Sato, K.; Kaye, S.; Choi, H.; Patel, N.; Brown, R.; Pitt, J. J.; Tan, D. S.; Jeyasekharan, A.
10.1101/2020.06.09.137612 — cancer biology — Posted on 2020-06-09
3694 Hippocampal hyperactivity in a rat model of Alzheimers disease
Sosulina, L.; Mittag, M.; Geis, H.-R.; Hoffmann, K.; Klyubin, I.; Qi, Y.; Steffen, J.; Friedrichs, D.; Henneberg, N.; Fuhrmann, F.; Justus, D.; Keppler, K.; Cuello, A. C.; Rowan, M.; Fuhrmann, M.; Remy, S.
10.1101/2020.06.09.141598 — neuroscience — Posted on 2020-06-09
3695 Multiple types of navigational information is diffusely and independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-06-09
3696 Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences
Priedigkeit, N.; Ding, K.; Horne, W.; Kolls, J. K.; Du, T.; Lucas, P. C.; Blohmer, J.-U.; Denkert, C.; Machleidt, A.; Ignold-Heppner, B.; Oesterreich, S.; Lee, A. V.
10.1101/2020.06.08.140707 — cancer biology — Posted on 2020-06-09
3699 Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures
Tapella, L.; Dematteis, G.; Ruffinatti, F. A.; Ponzoni, L.; Fiordaliso, F.; Corbelli, A.; Albanese, E.; Pistolato, B.; Pagano, J.; Barberis, E.; Marengo, E.; Balducci, C.; Forloni, G.; Verpelli, C.; Sala, C.; Distasi, C.; Sala, M.; Genazani, A. A.; Manfredi, M.; Lim, D.
10.1101/2020.03.21.001321 — neuroscience — Posted on 2020-06-09
3700 In silico saturation mutagenesis of cancer genes
Muinos, F.; Martinez-Jimenez, F.; Pich, O.; Gonzalez-Perez, A.; Lopez-Bigas, N.
10.1101/2020.06.03.130211 — cancer biology — Posted on 2020-06-09
3702 Polygenic adaptation and negative selection across traits, years and environments in a long-lived plant species (Pinus pinaster Ait., Pinaceae)
de Miguel, M.; Rodriguez-Quilon, I.; Heuertz, M.; Hurel, A.; Grivet, D.; Jaramillo-Correa, J. P.; Vendramin, G. G.; Plomion, C.; Majada, J.; Alia, R.; Eckert, A. J.; Gonzalez-Martinez, S. C.
10.1101/2020.03.02.974113 — genetics — Posted on 2020-06-09
3703 The heterogeneous landscape and early evolution of pathogen-associated CpG dinucleotides in SARS-CoV-2
Di Gioacchino, A.; Sulc, P.; Komarova, A. V.; Greenbaum, B. D.; Monasson, R.; Cocco, S.
10.1101/2020.05.06.074039 — genomics — Posted on 2020-06-09
3704 DISPERSE - A trait database to assess the dispersal potential of aquatic macroinvertebrates
Sarremejane, R.; Cid Puey, N.; Datry, T.; Stubbington, R.; Alp, M.; Canedo-Arguelles, M.; Cordero-Rivera, A.; Csabai, Z.; Gutierrez Canovas, C.; Heino, J.; Forcellini, M.; Millan, A.; Paillex, A.; Paril, P.; Polasek, M.; Tierno de Figueroa, J. M.; Usseglio-Polatera, P.; Zamora-Munoz, C.; Bonada, N.
10.1101/2020.02.21.953737 — ecology — Posted on 2020-06-09
3706 Molecular Docking Analysis Of Some Phytochemicals On Two SARS-CoV-2 Targets
Ubani, A.; Agwom, F.; Morenikeji, O. R.; Shehu, N. Y.; Luka, P.; Umera, E. A.; Umar, U.; Omale, S.; Nnadi, E.; Aguiyi, J. C.
10.1101/2020.03.31.017657 — bioinformatics — Posted on 2020-06-09
3711 Epigenetic Consequences of Hormonal Interactions between Opposite-sex Twin Fetuses
Kong, S.; Peng, Y.; Wei, C.; Ma, X.; Wei, Y.; Zhao, Y.; Li, R.; Yan, L.; Qiao, J.
10.1101/2020.06.09.141242 — developmental biology — Posted on 2020-06-09
3716 Evidence of progenitor cell lineage rerouting in the adult mouse hippocampus
Moura, D. M. S.; Brandao, J. A.; Lentini, C.; Heinrich, C.; Queiroz, C. M.; Costa, M. R.
10.1101/2020.06.08.140467 — neuroscience — Posted on 2020-06-09
3719 Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies
Hardenberg, M. C.; Sinnige, T.; Casford, S.; Dada, S.; Poudel, C.; Robinson, L.; Fuxreiter, M.; Kaminski, C. F.; Kaminski Schierle, G. S.; Nollen, E. A. A.; Dobson, C. M.; Vendruscolo, M.
10.1101/2020.06.08.140798 — molecular biology — Posted on 2020-06-09
3720 Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood
McCaffrey, E. F.; Donato, M.; Keren, L.; Chen, Z.; Fitzpatrick, M.; Jojic, V.; Delmastro, A.; Greenwald, N. F.; Baranski, A.; Graf, W.; Bosse, M.; Ramdial, P. K.; Forgo, E.; Van Valen, D.; van de Rijn, M.; Bendall, S. C.; Banaei, N.; Steyn, A. J. C.; Khatri, P.; Angelo, M.
10.1101/2020.06.08.140426 — immunology — Posted on 2020-06-09
3721 Hurricane-induced demographic changes in a nonhuman primate population
Morcillo, D. O.; Steiner, U. K.; Grayson, K. L.; Ruiz-Lambides, A. V.; Hernandez-Pacheco, R.
10.1101/2020.06.08.140566 — ecology — Posted on 2020-06-09
3724 A review of models of natural pest control: toward predictions across agricultural landscapes
Alexandridis, N.; Martin, E. A.; Marion, G.; Chaplin-Kramer, R.; Dainese, M.; Ekroos, J.; Grab, H.; Jonsson, M.; Karp, D. S.; Meyer, C.; O'Rourke, M. E.; Pontarp, M.; Poveda, K.; Seppelt, R.; Smith, H. G.; Clough, Y.
10.1101/2020.03.13.990531 — ecology — Posted on 2020-06-09
3728 Scalable method for micro-CT analysis enables large scale quantitative characterization of brain lesions and implants
Kastner, D. B.; Kharazia, V.; Nevers, R.; Astudillo-Maya, D. A.; Williams, G. M.; Yang, Z.; Smyth, C.; Della Santina, L.; Parkinson, D. Y.; Frank, L. M.
10.1101/2020.03.12.989871 — neuroscience — Posted on 2020-06-09
3729 Connectome subgraph isomorphisms and graph queries with DotMotif
Matelsky, J. K.; Reilly, E. P.; Johnson, E. C.; Wester, B. A.; Gray-Roncal, W.
10.1101/2020.06.08.140533 — neuroscience — Posted on 2020-06-09
3731 Structural basis of client specificity in mitochondrial membrane-protein chaperones
Sucec, I.; Wang, Y.; Dakhlaoui, O.; Weinhäupl, K.; Jores, T.; Costa, D.; Hessel, A.; Brennich, M.; Rapaport, D.; Lindorff-Larsen, K.; Bersch, B.; Schanda, P.
10.1101/2020.06.08.140772 — biophysics — Posted on 2020-06-09
3732 Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Luengo, A.; Li, Z.; Gui, D. Y.; Sullivan, L. B.; Zagorulya, M.; Do, B. T.; Ferriera, R.; Naamati, A.; Ali, A.; Lewis, C. A.; Thomas, C. J.; Spranger, S.; Matheson, N. J.; Vander Heiden, M. G.
10.1101/2020.06.08.140558 — biochemistry — Posted on 2020-06-09
3733 Internal state configures olfactory behavior and early sensory processing in Drosophila larvae
Vogt, K.; Zimmerman, D.; Schlichting, M.; Hernandez Nunez, L. A.; Qin, S.; Malacon, K.; Rosbash, M.; Pehlevan, C.; Cardona, A.; Samuel, A.
10.1101/2020.03.02.973941 — neuroscience — Posted on 2020-06-09
3735 The long non-coding RNA lnc-HLX-2-7 is oncogenic in group 3 medulloblastomas
KATSUSHIMA, K.; Lee, B.; Kunhiraman, H.; Zhong, C.; Murath, R.; Ying, J.; Liu, B.; Garancher, A.; Gonzalez-Gomez, I.; Stapleton, S.; Vibhakar, R.; Bettegowda, C.; Wechsler-Reya, R. J.; Jallo, G.; Raabe, E.; Eberhart, C. G.; Perera, R. J.
10.1101/2020.06.08.140251 — cancer biology — Posted on 2020-06-09
3736 Feature Extraction Approaches for Biological Sequences: A Comparative Study of Mathematical Models
Bonidia, R. P.; Sampaio, L. D. H.; Lopes, F. M.; de Carvalho, A. C. P. d. L. F.; Sanches, D. S.
10.1101/2020.06.08.140368 — bioinformatics — Posted on 2020-06-09
3741 The CBP KIX domain regulates long-term memory and circadian activity
Chatterjee, S.; Angelakos, C. C.; Bahl, E.; Hawk, J. D.; Gaine, M. E.; Poplawski, S. G.; Schneider-Anthony, A.; Yadav, M.; Porcari, G. S.; Cassel, J.-C.; Giese, K. P.; Michaelson, J. J.; Lyons, L. C.; Boutillier, A.-L.; Abel, T.
10.1101/2020.06.08.130815 — neuroscience — Posted on 2020-06-09
3744 aPKC drives cilia-independent Hedgehog signaling to maintain basal cell carcinoma growth
Nguyen, T. T.; Jeon, U. S.; Jhumkhawala, V.; Tan, K. C.; Kumar, V.; England, W. E.; Doan, L. T.; Spitale, R. C.; Atwood, S. X.
10.1101/2020.06.08.137216 — cancer biology — Posted on 2020-06-09
3748 Convergence of distinct subpopulations of mechanosensory neurons onto a neural circuit that elicits grooming
Hampel, S.; Eichler, K.; Yamada, D.; Kim, H.; Horigome, M.; Franconville, R.; Bock, D. D.; Kamikouchi, A.; Seeds, A. M.
10.1101/2020.06.08.141341 — neuroscience — Posted on 2020-06-09
3749 A single N6-methyladenosine site in lncRNA HOTAIR regulates its function in breast cancer cells
Porman, A. M.; Roberts, J. T.; Chrupcala, M.; Kennedy, M.; Williams, M. M.; Richer, J. K.; Johnson, A. M.
10.1101/2020.06.08.140954 — molecular biology — Posted on 2020-06-09
3750 Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality
Koch, C. M.; Anekalla, K.; Hu, J. Y.-S.; Ciesielski, M.; Gadhvi, G.; Chen, S.; Turner, M.; Cheng, Y.; Coates, B.; Abdala-Valencia, H.; Reyfman, P. A.; Misharin, A.; Budinger, G. S.; Winter, D. R.; Ridge, K. M.
10.1101/2020.06.08.141309 — immunology — Posted on 2020-06-09
3751 Activation-induced re-organization of chromatin in human T cells
Bediaga, N. G.; Coughlan, H. D.; Johanson, T. M.; Garnham, A. L.; Naseli, G.; Fearnley, L. G.; Schröder, J.; Bandala-Sanchez, E.; Allan, R. S.; Smyth, G. S.; Harrison, L. C.
10.1101/2020.06.08.135020 — genetics — Posted on 2020-06-09
3753 A new method for distinguishing human and mouse cells in situ
Wang, Y.; Huang, Z.; Hu, K.; Yun, P.; Yao, W.; Deng, W.; Zuo, J.; Zhang, Y.; Yin, D.
10.1101/2020.06.08.139204 — cell biology — Posted on 2020-06-09
3756 VirusDIP: Virus Data Integration Platform
Wang, L.; Chen, F.; Guo, X.; You, L.; Yang, X.; Yang, F.; Yang, T.; Gao, F.; Hua, C.; Ding, Y.; Cai, J.; Yang, L.; Huang, W.; Xu, Z.; Wan, B.; Tong, J.; Peng, C.; Yang, Y.; Zhang, L.; Liu, K.; Zhou, F.; Zhang, M.; Tan, C.; Zeng, W.; Wang, B.; Wei, X.
10.1101/2020.06.08.139451 — bioinformatics — Posted on 2020-06-09
3758 Interaction of dengue NS3 with human RNA silencing machinery through HSPA1A
Kakumani, P. K.; Shanmugam, R. K.; Chinnappan, M.; Kaur, I.; Chopra, A. P.; Malhotra, P.; Mukherjee, S.; Bhatnagar, R. K.
10.1101/2020.06.08.140590 — molecular biology — Posted on 2020-06-09
3759 Integrating remote sensing and jurisdictional observation networks to improve the resolution of ecological management
Townsend, P. A.; Clare, J.; Liu, N.; Stenglein, J.; Anhalt-Depies, C.; Van Deelen, T. R.; Gilbert, N. A.; Singh, A.; Martin, K. J.; Zuckerberg, B.
10.1101/2020.06.08.140848 — ecology — Posted on 2020-06-09
3760 Comparative Modeling of CDK9 Inhibitors to Explore Selectivity and Structure-Activity Relationships
Kirubakaran, P.; Morton, G.; Zhang, P.; Zhang, H.; Gordon, J.; Abou-Gharbia, M.; Issa, J.-P. J.; Wu, J.; Childers, W.; Karanicolas, J.
10.1101/2020.06.08.138602 — cancer biology — Posted on 2020-06-09
3761 Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited
Li, Z.; Ji, B. W.; Dixit, P. D.; Lien, E. C.; Tchourine, K.; Hosios, A. M.; Abbott, K. L.; Westermark, A. M.; Gorodetsky, E. F.; Sullivan, L. B.; Vander Heiden, M.; Vitkup, D.
10.1101/2020.06.08.134890 — cancer biology — Posted on 2020-06-09
3763 Spritz: A Proteogenomic Database Engine
Cesnik, A. J.; Miller, R. M.; Ibrahim, K.; Lu, L.; Millikin, R. J.; Shortreed, M. R.; Frey, B. L.; Smith, L. M.
10.1101/2020.06.08.140681 — bioinformatics — Posted on 2020-06-09
3767 Slow oscillation-spindle coupling impairs emotional memory consolidation following stress
Denis, D.; Kim, S. Y.; Kark, S. M.; Daley, R. T.; Kensinger, E. A.; Payne, J. D.
10.1101/2020.06.08.140350 — neuroscience — Posted on 2020-06-09
3771 treeclimbR pinpoints the data-dependent resolution of hierarchical hypotheses
Huang, R.; Soneson, C.; Germain, P.-L.; Schmidt, T. S.; von Mering, C.; Robinson, M. D.
10.1101/2020.06.08.140608 — bioinformatics — Posted on 2020-06-09
3774 Dorsal horn CGRP-expressing interneurons contribute to nerve injury-induced mechanical hypersensitivity
Löken, L. S.; Etlin, A.; Bernstein, M.; Steyert, M.; Kuhn, J.; Hamel, K.; Llewellyn-Smith, I.; Braz, J. M.; Basbaum, A. I.
10.1101/2020.06.08.131839 — neuroscience — Posted on 2020-06-09
3776 TBPL2/TFIIA complex overhauls oocyte transcriptome during oocyte growth
Yu, C.; Cvetesic, N.; Gupta, K.; Ye, T.; Gazdag, E.; Hisler, V.; Negroni, L.; Hajkova, P.; Lenhard, B.; Mueller, F.; Berger, I.; Vincent, S. D.; Tora, L.
10.1101/2020.06.08.118984 — molecular biology — Posted on 2020-06-09
3780 High developmental temperature leads to low reproduction despite adult temperature
Santos, M. A.; Carromeu-Santos, A.; Quina, A. S.; Santos, M.; Matos, M.; Simoes, P.
10.1101/2020.06.08.140277 — evolutionary biology — Posted on 2020-06-09
3783 PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
Park, P.; Georgiou, J.; Sanderson, T. M.; Ko, K.-H.; Kang, H.; Kim, J.-i.; Bradley, C. A.; Bortolotto, Z. A.; Zhuo, M.; Kaang, B.-K.; Collingridge, G. L.
10.1101/2020.06.08.136762 — neuroscience — Posted on 2020-06-09
3785 Modelling fibrillogenesis of collagen-mimetic molecules
Hafner, A. E.; Gyori, N. G.; Bench, C. A.; Davis, L. K.; Saric, A.
10.1101/2020.06.08.140061 — biophysics — Posted on 2020-06-09
3786 Screening of PCRP transcription factor antibodies in biochemical assays
Lai, W.; Mariani, L.; Rothschild, G.; Smith, E.; Venters, B.; Blanda, T.; Kuntala, P.; Bocklund, K.; Mairose, J.; Dweikat, S.; Mistretta, K.; Rossi, M.; James, D.; Anderson, J.; Phanor, S.; Zhang, W.; Shaw, A.; Novitzky, K.; McAnarney, E.; Keogh, M.-C.; Shilatifard, A.; Basu, U.; Bulyk, M.; Pugh, B. F.
10.1101/2020.06.08.140046 — biochemistry — Posted on 2020-06-09
3790 miR-218 in adolescence predicts and mediates vulnerability to stress
Torres-Berrio, A.; Morgunova, A.; Giroux, M.; Cuesta, S.; Nestler, E. J.; Flores, C.
10.1101/2020.06.08.140038 — neuroscience — Posted on 2020-06-09
3791 Attention in Motion: Using an Oddball Task to Record Brain Activity in Skateboarders
Robles, D.; Kuziek, J. W. P.; Wlasitz, N. A.; Bartlett, N. T.; Hurd, P. L.; Mathewson, K. E.
10.1101/2020.06.08.136960 — neuroscience — Posted on 2020-06-09
3792 Single-cell RNA transcriptomics identifies Hivep3 as essential in regulating the development of innate-like T lymphocytes
Krovi, S. H.; Zhang, J.; Michaels-Foster, M. J.; Brunetti, T.; Loh, L.; Scott-Browne, J.; Gapin, L.
10.1101/2020.06.08.135129 — immunology — Posted on 2020-06-09
3794 Mitophagy protects beta cells from inflammatory damage in diabetes
Sidarala, V.; Pearson, G. L.; Parekh, V. S.; Thompson, B.; Christen, L.; Gingerich, M. A.; Zhu, J.; Stromer, T.; Ren, J.; Reck, E.; Chai, B.; Corbett, J. A.; Mandrup-Poulsen, T.; Satin, L. S.; Soleimanpour, S. A.
10.1101/2020.06.07.138917 — cell biology — Posted on 2020-06-09
3798 Differential causal involvement of human auditory and frontal cortices in vocal motor control
Cardenas, A. R.; Behroozmand, R.; Kocsis, Z.; Gander, P. E.; Nourski, K. V.; Kovach, C. K.; Ibayashi, K.; Pipoly, M.; Kawasaki, H.; Howard, M. A.; Greenlee, J. D.
10.1101/2020.06.08.139881 — neuroscience — Posted on 2020-06-09
3799 Altered Thalamocortical Connectivity in Six-Week Old Infants at High Familial Risk for Autism Spectrum Disorder
Nair, A.; Jalal, R.; Liu, J.; Tsang, T.; McDonald, N.; Jackson, L.; Ponting, C.; Jeste, S.; Bookheimer, S.; Dapretto, M.
10.1101/2020.06.07.139147 — neuroscience — Posted on 2020-06-09
3801 Multi-ancestry Genome- and Phenome-wide Association Studies of Diverticular Disease in Electronic Health Records with Natural Language Processing enriched phenotype algorithm
Joo, Y. Y.; Pacheco, J. A.; Thompson, W. K.; Rasmussen-Torvik, L.; Rasmussen, L. V.; Lin, F. T.; Andrade, M. d.; Borthwick, K. M.; Bottinger, E.; Cagan, A.; Carrell, D. S.; Denny, J. C.; Ellis, S. B.; Gottesman, O.; Linneman, J. G.; Pathak, J.; Peissig, P. L.; Shang, N. S.; Tromp, G.; Veerappan, A.; Smith, M.; Chisholm, R. L.; Gawron, A. J.; Kho, A. N.; Hayes, M. G.
10.1101/2020.06.08.138735 — bioinformatics — Posted on 2020-06-09
3804 SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways
Serbyn, N.; Bagdiul, I.; Michel, A. H.; Suhandynata, R. T.; Zhou, H.; Kornmann, B.; Stutz, F.
10.1101/2020.06.08.140079 — molecular biology — Posted on 2020-06-09
3805 An Inexpensive RT-PCR Endpoint Diagnostic Assay for SARS-CoV-2 Using Nested PCR: Direct Assessment of Detection Efficiency of RT-qPCR Tests and Suitability for Surveillance
Davda, J. N.; Frank, K.; Prakash, S.; Purohit, G.; Vijayashankar, D. P.; Vedagiri, D.; Tallapaka, K. B.; Harshan, K. H.; Siva, A. B.; Mishra, R. K.; Dhawan, J.; Siddiqi, I.
10.1101/2020.06.08.139477 — molecular biology — Posted on 2020-06-09
3806 FasR regulates fatty acid biosynthesis and is essential for virulence of Mycobacterium tuberculosis
Mondino, S.; Vazquez, C. L.; Cabruja, M.; Sala, C.; Cazenave-Gassiot, A.; Blanco, F. C.; Wenk, M. R.; Cole, S.; Bigi, F.; Gramajo, H.; Gago, G.
10.1101/2020.06.08.140004 — microbiology — Posted on 2020-06-09
3807 The genetic signatures of Salmonella Typhi carriage in the human gallbladder
Thanh Duy, P.; Tran Vu Thieu, N.; Thi Nguyen To, N.; Ngoc Dan Thanh, H.; Dongol, S.; Karkey, A.; Carey, M.; Basnyat, B.; Dougan, G.; Rabaa, M. A.; Baker, S.
10.1101/2020.06.08.140053 — microbiology — Posted on 2020-06-09
3809 Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014
Huong, N. Q.; Nga, N. T. T.; Long, N. V.; Luu, B. D.; Latinne, A.; Pruvot, M.; Phuong, N. T.; Quang, L. T. V.; Hung, V. V.; Lan, N. T.; Hoa, N. T.; Minh, P. Q.; Diep, N. T.; Tung, N.; Ky, V. D.; Roberton, S. I.; Thuy, H. B.; Long, N. V.; Gilbert, M.; Wicker, L.; Mazet, J. A. K.; Johnson, C. K.; Goldstein, T.; Tremeau-Bravard, A.; Ontiveros, V.; Joly, D. O.; Walzer, C.; Fine, A. E.; Olson, S. H.
10.1101/2020.06.05.098590 — microbiology — Posted on 2020-06-09
3810 Baseline epidemiology and associated dog ecology study towards stepwise elimination of rabies in Kwara state, Nigeria
Al-Mustapha, A. I.; Tijani, A. A.; Oyewo, M.; Bamidele, F. O.; Ibrahim, A.; Osu, M. S.; Olugasa, B.; Balogun, M. S. I.; Kia, G.; Mazeri, S.; Heikinheimo, A.
10.1101/2020.06.08.140517 — microbiology — Posted on 2020-06-09
3813 DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification
Decamps, C.; Arnaud, A.; Petiprez, F.; Ayadi, M.; Baures, A.; Armenoult, L.; HADACA consortium, ; Nicolle, R.; Tomasini, R.; De Reynies, A.; Cros, J.; Blum, Y.; Richard, M.
10.1101/2020.06.06.131482 — bioinformatics — Posted on 2020-06-09
3816 A temporal record of the past with a spectrum of time constants in the monkey entorhinal cortex
Bright, I. M.; Meister, M. L. R.; Cruzado, N. A.; Tiganj, Z.; Buffalo, E. A.; Howard, M. W.
10.1101/688341 — neuroscience — Posted on 2020-06-09
3821 Temporal transcriptome profiling of Microchloropsis gaditana CCMP526 under hyper-saline conditions
Karthikaichamy, A.; Beardall, J.; Coppel, R.; Noronha, S.; Srivastava, S.; Bulach, D.
10.1101/2020.06.07.139238 — microbiology — Posted on 2020-06-09
3824 ROSeq: Modeling expression ranks for noise-tolerantdifferential expression analysis of scRNA-Seq data
Gupta, K.; Lalit, M.; Biswas, A.; Maulik, U.; Bandyopadhyay, S.; Ahuja, G.; Ghosh, A.; Sengupta, D.
10.1101/374025 — genomics — Posted on 2020-06-08
3825 The dynamics of spawning acts by a semelparous fish and its associated energetic expenses
Tentelier, C.; Bouchard, C.; Bernardin, A.; Tauzin, A.; Aymes, J.-C.; Lange, F.; Recapet, C.; Rives, J.
10.1101/436295 — ecology — Posted on 2020-06-08
3827 Double Emulsion Picoreactors for High-Throughput Single-Cell Encapsulation and Phenotyping via FACS
Brower, K. K.; Khariton, M.; Suzuki, P. H.; Still, C.; Kim, G.; Calhoun, S. G.; Qi, L. S.; Wang, B.; Fordyce, P. M.
10.1101/2020.06.07.139311 — bioengineering — Posted on 2020-06-09
3828 Aging interacts with tumor biology to produce major changes in the immune tumor microenvironment
Erbe, R.; Wang, Z.; Zaidi, N.; Topper, M.; Baylin, S.; Jaffee, E.; Easwaran, H.; Fertig, E. J.
10.1101/2020.06.08.140764 — cancer biology — Posted on 2020-06-08
3836 Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer
Punturi, N. B.; Seker, S.; Devarakonda, V.; Kalra, R.; Chen, C.-H.; Mazumder, A.; Li, S.-Q.; Primeau, T.; Ellis, M. J.; Kavuri, S. M.; Haricharan, S.
10.1101/2020.06.08.128090 — cancer biology — Posted on 2020-06-08
3838 Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide
Isabel, S.; Grana-Miraglia, L.; Gutierrez, J. M.; Bundalovic-Torma, C.; Groves, H. E.; Isabel, M. R.; Eshaghi, A.; Patel, S. N.; Gubbay, J. B.; Poutanen, T.; Guttman, D. S.; Poutanen, S. M.
10.1101/2020.06.08.140459 — bioinformatics — Posted on 2020-06-08
3839 Multivariate 'AND-gate' substrate probes as enhanced contrast agents for fluorescence-guided surgery
Widen, J. C.; Tholen, M.; Yim, J. J.; antaris, A.; Casey, K. M.; Rogalla, S.; Klaassen, A.; Sorger, J.; Bogyo, M.
10.1101/695403 — bioengineering — Posted on 2020-06-08
3840 Split-HaloTag Imaging Assay for in vivo 3D-Microscopy and Subdiffractional Analyses of Protein-Protein Interactions
Meinen, R.; Weber, J. N.; Albrecht, A.; Matis, R.; Behnecke, M.; Tietge, C.; Frank, S.; Schulze, J.; Buschmann, H.; Walla, P. J.; Mendel, R. R.; Haensch, R.; Kaufholdt, D.
10.1101/2020.06.08.139378 — plant biology — Posted on 2020-06-08
3841 Inflammation and epigenetic age in Alzheimer's disease: do sex and APOE matter?
Duarte-Guterman, P.; Inkster, A. M.; Albert, A. Y.; Barha, C. K.; Robinson, W.; Galea, L.
10.1101/741777 — neuroscience — Posted on 2020-06-08
3843 Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis
Wright, A. L.; Della Gatta, P.; Le, S.; Berning, B. A.; Mehta, P.; Jacobs, K. R.; Gul, H.; San Gil, R.; Hedl, T. J.; Riddell, W. R.; Watson, O.; Keating, S. S.; Venturato, J.; Chung, R. S.; Atkin, J. D.; Lee, A.; Shi, B.; Blizzard, C. A.; Morsch, M.; Walker, A. K.
10.1101/749846 — neuroscience — Posted on 2020-06-08
3844 Effects of mid-frontal brain stimulation on sustained attention
van Schouwenburg, M. R.; Sligte, I. G.; Giffin, M. R.; Gunther, F.; Koster, D.; Spronkers, F. S.; Vos, A.; Slagter, H. A.
10.1101/641498 — neuroscience — Posted on 2020-06-08
3848 Quantifying fluorescent glycan uptake to elucidate strain-level variability in foraging behaviors of rumen bacteria
Klassen, L.; Reintjes, G.; Tingley, J. P.; Jones, D. R.; Hehemann, J.-H.; Smith, A. D.; Schwinghamer, T. D.; Arnosti, C.; Jin, L.; Alexander, T. W.; Amundsen, C.; Thomas, D.; Amann, R.; McAllister, T. A.; Abbott, D. W.
10.1101/2020.06.08.140780 — microbiology — Posted on 2020-06-08
3849 SARS-CoV-2 Whole Genome Amplification and Sequencing for Effective Population-Based Surveillance and Control of Viral Transmission
Harilal, D.; Ramaswamy, S.; Loney, T.; Varghese, R.; Deesi, Z.; Nowotny, N.; Alsheikh-Ali, A.; Abou Tayoun, A.
10.1101/2020.06.06.138339 — genomics — Posted on 2020-06-08
3850 Zinc protection of fertilized eggs is an ancient feature of sexual reproduction in animals
Wozniak, K. L.; Bainbridge, R. E.; Summerville, D. W.; Tembo, M.; Phelps, W. A.; Sauer, M. L.; Wisner, B. W.; Caekalski, M. E.; Pasumarthy, S.; Hanson, M. L.; Linderman, M. B.; Luu, C. H.; Boehm, M. E.; Sanders, S. M.; Buckley, K. M.; Bain, D. J.; Nicotra, M. L.; Lee, M. T.; Carlson, A. E.
10.1101/2020.06.08.140541 — physiology — Posted on 2020-06-08
3851 Precise Localization and Dynamic Distribution of Japanese Encephalitis Virus in theBrain Nuclei of Infected Mice
Changqin, G.; Han, W.; Gao, M.; Xie, C.; Zhang, J.; Zhao, Z.; Hu, X.; Zhang, W.; Liu, X.; Cao, S.; Cheng, G.
10.1101/2020.06.08.139824 — pathology — Posted on 2020-06-08
3852 Model-based prediction of muscarinic receptor function from auditory mismatch negativity responses
Schöbi, D.; Jung, F.; Frässle, S.; Endepols, H.; Moran, R. J.; Friston, K. J.; Tittgemeyer, M.; Heinzle, J.; Stephan, K. E.
10.1101/2020.06.08.139550 — neuroscience — Posted on 2020-06-08
3857 A consensus-based ensemble approach to improve de novo transcriptome assembly
Voshall, A.; Behera, S.; Li, X.; Yu, X.-H.; Kapil, K.; Deogun, J. S.; Schanklin, J.; Cahoon, E. B.; Moriyama, E. N.
10.1101/2020.06.08.139964 — bioinformatics — Posted on 2020-06-08
3858 Design of optical imaging probes by screening of diverse substrate libraries directly in disease tissue extracts
Tholen, M.; Yim, J. J.; Groborz, K.; Yoo, E.; Martin, B. A.; van den Berg, N. S.; Drag, M.; Bogyo, M.
10.1101/2020.06.08.140947 — bioengineering — Posted on 2020-06-08
3859 Enhanced production of taxadiene in Saccharomyces cerevisiae
Nowrouzi, B.; Li, R.; Walls, L. E.; d'Espaux, L.; Malci, K.; Liang, L.; Jonguitud Borrego, N.; Lerma Escalera, A. I.; Morones-Ramirez, J. R.; Keasling, J. D.; Rios Solis, L.
10.1101/2020.06.08.139600 — synthetic biology — Posted on 2020-06-08
3863 Functional and molecular early enteric biomarkers for Parkinson's disease in mice and men
Gries, M.; Christmann, A.; Schulte, S.; Weyland, M.; Rommel, S.; Martin, M.; Baller, M.; Roeth, R.; Schmitteckert, S.; Unger, M.; Liu, Y.; Sommer, F.; Muehlhaus, T.; Schroda, M.; Timmermans, J.-P.; Pintelon, I.; Rappold, G. A.; Britschgi, M.; Lashuel, H.; Menger, M. D.; Laschke, M. W.; Niesler, B.; Schaefer, K.-H.
10.1101/2020.06.06.136556 — neuroscience — Posted on 2020-06-08
3874 Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes
Roll-Mecak, A.; Mahalingan, K. K.; Keenan, E. K.; Strickland, M.; Li, Y.; Liu, Y.; Ball, H.; Tanner, M. E.; Tjandra, N.
10.1101/2020.06.07.139295 — biochemistry — Posted on 2020-06-08
3875 Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Acosta-Serrano, A.; Sterkel, M.; Haines, L.; Casas-Sanchez, A.; Owino, V.; Vionette-Amaral, R.; Quek, S.; Rose, C.; Silva dos Santos, M.; Garcia Escude, N.; Ismail, H.; Paine, M. I.; Barribeau, S. M.; Wagstaff, S.; MacRae, J. I.; Masiga, D.; Yakob, L.; Oliveira, P. L.
10.1101/2020.06.08.139808 — biochemistry — Posted on 2020-06-08
3877 Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells
Novo, C. L.; Wong, E.; Hockings, C.; Poudel, C.; Sheekey, E.; Walker, S.; Kaminski Schierle, G. S.; Narlikar, G.; Rugg-Gunn, P.
10.1101/2020.06.08.139642 — molecular biology — Posted on 2020-06-08
3879 Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer
Borgoni, S.; Sofyali, E.; Soleimani Dodaran, M.; Wilhelm, H.; Mueller-Decker, K.; Will, R.; Noronha, A.; Verschure, P. J.; Yarden, Y.; Magnani, L.; van Kampen, A. H. C.; Moerland, P. D.; Wiemann, S.
10.1101/2020.06.08.139659 — cancer biology — Posted on 2020-06-08
3882 Metabolic plasticity in cancer activates apocryphal pathways for lipid desaturation
Young, R. S. E.; Bowman, A. P.; Williams, E. D.; Tousignant, K. D.; Bidgood, C. L.; Narreddula, V. R.; Gupta, R.; Marshall, D. L.; Poad, B. L.; Nelson, C. C.; Ellis, S. R.; Heeren, R. M.; Sadowski, M.; Blanksby, S. J.
10.1101/2020.06.07.139089 — biochemistry — Posted on 2020-06-08
3883 Localization of hyphal growth associated with mycotoxin production during the malting of Fusarium head blight infected grains
Zhao, J.; Solanki, S.; Ameen, G.; Gross, T.; Sharma Poudel, R.; Borowicz, P.; Brueggeman, R. S.; Schwarz, P.
10.1101/2020.06.06.126979 — plant biology — Posted on 2020-06-08
3884 Computational Support, Not Primacy, Distinguishes Compensatory Memory Reorganization in Epilepsy
Tracy, J.; Chaudhary, K.; Modi, S.; Crow, A.; Kumar, A.; Weinstein, D.; Sperling, M.
10.1101/2020.06.07.138594 — neuroscience — Posted on 2020-06-08
3887 Transduction catalysis: doxorubicin accelerates and enhances rAAV-mediated gene expression in the cortex of mouse, cat and monkey
gong, h.; Yuan, N.; Shen, Z.; Tang, C.; Shipp, S.; Qian, L.; Lu, Y.; Andolina, I. M.; Zhang, S.; Wu, J.; Yang, H.; Wang, W.
10.1101/2020.06.08.139667 — neuroscience — Posted on 2020-06-08
3890 Impact of trimethoprim on the river microbiome and antimicrobial resistance.
Delaney, J.; Raguideau, S.; Holden, J.; Zhang, L.; Tipper, H.; Hill, G.; Klumper, U.; Zhang, T.; James, R. S.; Travis, E. R.; Bowes, M. J.; Hawkey, P. M.; Lindstrom, H. S.; Tang, C.; Gaze, W. H.; Mead, A.; Quince, C. R.; Singer, A. C.; Wellington, E. M.
10.1101/2020.06.05.133348 — microbiology — Posted on 2020-06-08
3892 Genomics of Ocular Chlamydia trachomatis after 5 years of SAFE interventions for trachoma in Amhara, Ethiopia
Pickering, H.; Chernet, A.; Sata, E.; Zerihun, M.; Williams, C. A.; Breuer, J.; Nute, A. W.; Haile, M.; Zeru, T.; Tadesse, Z.; Bailey, R. L.; Callahan, E. K.; Holland, M. J.; Nash, S. D.
10.1101/2020.06.07.138982 — genomics — Posted on 2020-06-08
3893 Multiple, independent, common variants overlapping known and putative gut enhancers at RET, SEMA3 and NRG1 underlie Hirschsprung disease risk in European ancestry subjects
Kapoor, A.; Nandakumar, P.; Auer, D.; Sosa, M.; Ross, H.; Bollinger, J.; Yan, J.; Berrios, C.; The Hirschsprung Disease Research Collaborative (HDRC), ; Chakravarti, A.
10.1101/2020.06.07.138719 — genetics — Posted on 2020-06-08
3895 A novel assay for tracking carboxylesterase gene amplifications conferring organophosphate resistance in the mosquito Aedes aegypti: from experimental evolution to field application
Cattel, J.; Haberkorn, C.; Laporte, F.; Gaude, T.; Cumer, T.; Renaud, J.; Sutherland, I. W.; Hertz, J. C.; Bonneville, J.-M.; Arnaud, V.; Nous, C.; Fustec, B.; Boyer, S.; Marcombe, S.; David, J.-P.
10.1101/2020.06.08.139741 — evolutionary biology — Posted on 2020-06-08
3897 Incorporating climate velocity into the design of climate-smart networks of protected areas
Arafeh-Dalmau, N.; Brito-Morales, I.; Schoeman, D. S.; Possingham, H. P.; Klein, C. J.; Richardson, A. J.
10.1101/2020.06.08.139519 — ecology — Posted on 2020-06-08
3898 eDNA metabarcoding reveals a core and secondary diets of the greater horseshoe bat with strong spatio-temporal plasticity
Tournayre, O.; Leuchtmann, M.; Galan, M.; Trillat, M.; Piry, S.; Pinaud, D.; Filippi-Codaccioni, O.; Pontier, D.; Charbonnel, N.
10.1101/2020.06.08.139584 — ecology — Posted on 2020-06-08
3900 Spatially discrete signalling niches regulate fibroblast heterogeneity in human lung cancer
Hanley, C. J.; Waise, S.; Parker, R.; Lopez, M. A.; Taylor, J.; Kimbley, L.; West, J.; Ottensmeier, C. H.; Rose-Zerilli, M. J.; Thomas, G. J.
10.1101/2020.06.08.134270 — cancer biology — Posted on 2020-06-08
3901 Recurrent Dynamics of Rupture Transitions of Single Giant Vesicles at Solid Surfaces
Ngassam, V. N.; Su, W.-C.; Gettel, D.; Deng, Y.; Yang, Z.; Wang-Tomic, N.; Sharma, V. P.; Purushothaman, S.; Parikh, A. N.
10.1101/2020.06.08.140178 — biophysics — Posted on 2020-06-08
3902 Decomposing metabolite set activity levels with PALS
McLuskey, K.; Wandy, J.; Vincent, I.; van der Hooft, J. J. J.; Rogers, S.; Burgess, K.; Daly, R.
10.1101/2020.06.07.138974 — bioinformatics — Posted on 2020-06-08
3903 A single-cell RNA-seq Training and Analysis Suite using the Galaxy Framework
Tekman, M.; Batut, B.; Ostrovsky, A.; Antoniewski, C.; Clements, D.; Ramirez, F.; Etherington, G. J.; Hotz, H.-R.; Scholtalbers, J.; Manning, J. R.; Bellenger, L.; Doyle, M. A.; Heydarian, M.; Huang, N.; Soranzo, N.; Moreno, P.; Papatheodorou, I.; Nekrutenko, A.; Taylor, J.; Blankenberg, D.; Backofen, R.; Grüning, B.
10.1101/2020.06.06.137570 — bioinformatics — Posted on 2020-06-08
3905 Wide-field Fluorescence Lifetime Imaging Microscopy with a High-Speed Mega-pixel SPAD Camera
Zickus, V.; Wu, M. L.; Morimoto, K.; Kapitany, V.; Farima, A.; Turpin, A.; Insall, R.; Whitelaw, J.; Machesky, L.; Bruschini, C.; Faccio, D.; Charbon, E.
10.1101/2020.06.07.138685 — bioengineering — Posted on 2020-06-08
3908 Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids
Renne, M. F.; Bao, X.; Hokken, M. W.; Bierhuizen, A. S.; Hermansson, M.; Ewing, T.; Ma, X.; Cox, R. C.; Brouwers, J. F.; De Smet, C. H.; Ejsing, C. S.; de Kroon, A. I.
10.1101/2020.06.08.140129 — biochemistry — Posted on 2020-06-08
3913 Elementary Conversion Modes enable exploration of all metabolic capabilities of any organism
Clement, T. J.; Baalhuis, E. B.; Teusink, B.; Bruggeman, F. J.; Planque, R.; de Groot, D. H.
10.1101/2020.06.06.137554 — systems biology — Posted on 2020-06-08
3914 BioDynaMo: an agent-based simulation platform for scalable computational biology research
Breitwieser, L.; Hesam, A.; de Montigny, J.; Vavourakis, V.; Iosif, A.; Jennings, J.; Kaiser, M.; Manca, M.; Di Meglio, A.; Al-Ars, Z.; Rademakers, F.; Mutlu, O.; Bauer, R.
10.1101/2020.06.08.139949 — systems biology — Posted on 2020-06-08
3917 Fentanyl-induced antinociception, reward, reinforcement, and withdrawal in Hnrnph1 mutant mice
Bryant, C. D.; Healy, A. F.; Ruan, Q. T.; Coehlo, M. A.; Lustig, E.; Yazdani, N.; Luttik, K. P.; Tran, T.; Swancy, I.; Brewin, L. W.; Chen, M. M.; Szumlinski, K. K.
10.1101/2020.06.06.137158 — neuroscience — Posted on 2020-06-08
3921 Closed-loop fMRI neurofeedback to reduce negative attentional bias in depression
Mennen, A. C.; Turk-Browne, N. B.; Wallace, G.; Seok, D.; Jaganjac, A.; Stock, J.; deBettencourt, M. T.; Cohen, J. D.; Norman, K. A.; Sheline, Y. I.
10.1101/2020.06.07.137943 — neuroscience — Posted on 2020-06-08
3922 Nitric oxide, KATP channels and endothelin-1 modulate brain pericyte function, vascular tone and neurovascular coupling
Zambach, S. A.; Cai, C.; Helms, H. C. C.; Hald, B. O.; Fordsmann, J. C.; Murmu Nielsen, R.; Loenstrup, M.; Brodin, B.; Lauritzen, M.
10.1101/2020.06.07.138875 — neuroscience — Posted on 2020-06-08
3925 Unsupervised Neural Tracing in Densely Labeled Multispectral Brainbow Images
Duan, B.; Walker, L. A.; Roosien, D. H.; Shen, F. Y.; Cai, D.; Yan, Y.
10.1101/2020.06.07.138941 — neuroscience — Posted on 2020-06-08
3927 Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike
Prevost, J.; Gasser, R.; Beaudoin-Bussieres, G.; Richard, J.; Duerr, R.; Laumaea, A.; Anand, S. P.; Goyette, G.; Ding, S.; Medjahed, H.; Lewin, A.; Perreault, J.; Tremblay, T.; Gendron-Lepage, G.; Gauthier, N.; Carrier, M.; Marcoux, D.; Piche, A.; Lavoie, M.; Benoit, A.; Loungnarath, V.; Brochu, G.; Desforges, M.; Talbot, P. J.; Gould Maule, G. T.; Cote, M.; Therrien, C.; Serhir, B.; Bazin, R.; Roger, M.; Finzi, A.
10.1101/2020.06.08.140244 — microbiology — Posted on 2020-06-08
3928 Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
Tandon, R.; Sharp, J. S.; Zhang, F.; Pomin, V. H.; Ashpole, N. M.; Mitra, D.; Jin, W.; Liu, H.; Sharma, P.; Linhardt, R. J.
10.1101/2020.06.08.140236 — microbiology — Posted on 2020-06-08
3930 SARS-CoV-2-specific T cells exhibit unique features characterized by robust helper function, lack of terminal differentiation, and high proliferative potential
Neidleman, J.; Luo, X.; Frouard, J.; Xie, G.; Gurjot, G.; Stein, E. S.; McGregor, M.; Ma, T.; George, A.; Kosters, A.; Greene, W. C.; Vasquez, J.; Ghosn, E.; Lee, S.; Roan, N. R.
10.1101/2020.06.08.138826 — immunology — Posted on 2020-06-08
3931 Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.
Dong, T.; Peng, Y.; Mentzer, A. J.; Liu, G.; Yao, X.; Yin, Z.; Dong, D.; Dejnirattisai, W.; Turtle, L.; Rostron, T.; Subramaniam, K.; Thomson, P.; Zhang, P.; Dold, C.; Ratcliff, J.; de Silva, T.; Sopp, P.; Wellington, D.; Rajapaksa, U.; Paes, W.; Borrow, P.; Kessler, B. M.; Fry, J. W.; Schwabe, N. F.; Semple, M. G.; Baillie, J. K.; Openshaw, P. J.; Cornall, R. J.; Conlon, C.; Screaton, G.; Klenerman, P.; Mongkolsapaya, J.; McMichael, A.; Knight, J. C.; Ogg, G.; Simmonds, P.; Lockett, T.; Levin, R.; Moore, S. C.; Salio, M.; Napolitani, G.; Chen, Y.-L.; Dunachie, S.; Supasa, P.; Liu, C.; Lopez-C
10.1101/2020.06.05.134551 — immunology — Posted on 2020-06-08
3932 NCOA3 identified as a new candidate to explain autosomal dominant progressive hearing loss
da Silva, R. S.; Dantas, V. L.; Alves, L. U.; Batissoco, A. C.; Oiticica, J.; Lawrence, E. A.; Kawafi, A.; Yang, Y.; Nicastro, F. S.; Novaes, B. C.; Hammond, C. L.; Kague, E.; Netto, R. C. M.
10.1101/2020.06.07.138909 — genetics — Posted on 2020-06-08
3934 Kinome Profiling of Gastrointestinal Stromal Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies Wee1 as Candidate Therapeutic Target
Ye, S.; Sharipova, D.; Kozinova, M.; Klug, L.; D'Souza, J.; Belinsky, M. G.; Johnson, K. J.; Einarson, M. B.; Cai, K.; Devarajan, K.; Zhou, Y.; Litwin, S.; Heinrich, M. C.; DeMatteo, R.; von Mehren, M.; Duncan, J.; Rink, L.
10.1101/2020.06.07.138693 — cancer biology — Posted on 2020-06-08
3935 Structure Basis for Inhibition of SARS-CoV-2 by the Feline Drug GC376
Luan, X.; Shang, W.; Wang, Y.; Yin, W.; Jiang, Y.; Feng, S.; Wang, Y.; Liu, M.; Zhou, R.; Zhang, Z.; Wang, F.; Wang, C.; Gao, M.; Wang, H.; Wu, W.; Tian, R.; Tian, Z.; Jin, Y.; Jiang, H.; Zhang, L.; Xu, H. E.; Zhang, S.
10.1101/2020.06.07.138677 — biophysics — Posted on 2020-06-08
3937 Analysis of single-cell RNA-seq data from ovarian cancer samples before and after chemotherapy links stress-related transcriptional profile withchemotherapy resistance
Zhang, K.; Erkan, E. P.; Dai, J.; Andersson, N.; Kaipio, K.; Lamminen, T.; Mansuri, N.; Huhtinen, K.; Carpen, O.; Hynninen, J.; Hietanen, S.; Oikkonen, J.; Hakkinen, A.; Hautaniemi, S.; Vaharautio, A.
10.1101/2020.06.06.138362 — bioinformatics — Posted on 2020-06-08
3940 The Impact of Restriction-Modification Systems on Mating in Haloferax volcanii
Ouellette, M.; Makkay, A. M.; Louyakis, A. S.; Gophna, U.; Gogarten, J. P.; Papke, R. T.
10.1101/2020.06.06.138198 — evolutionary biology — Posted on 2020-06-08
3941 Drug2ways: Reasoning over causal paths in biological networks for drug discovery
Rivas-Barragan, D.; Mubeen, S.; Guim-Bernat, F.; Hofmann-Apitius, M.; Domingo-Fernandez, D.
10.1101/2020.06.07.138388 — bioinformatics — Posted on 2020-06-08
3944 The First complete Zoroastrian-Parsi Mitochondria Reference Genome: Implications of mitochondrial signatures in an endogamous, non-smoking population
Morawala-Patell, V.; Pasha, N. S.; Krishnasamy, K.; Mittal, B.; Gopalakrishnan, C.; Mugasimangalam, R.; Sharma, N.; Khanna-Gupta, A.; Bhote-Patell, P.; Rao, S. N.; Jain, R.
10.1101/2020.06.05.124891 — genomics — Posted on 2020-06-08
3947 Evidence for reduced long-term potentiation-like visual cortical plasticity in schizophrenia and bipolar disorder
Valstad, M.; Roelfs, D.; Slapo, N. B.; Timpe, C. M. F.; Rai, A.; Matziorinis, A. M.; Beck, D.; Richard, G.; Saether, L. S.; Haatveit, B.; Nordvik, J. E.; Hatlestad-Hall, C.; Einevoll, G. T.; Mäki-Marttunen, T.; Haram, M.; Ueland, T.; Lagerberg, T. V.; Steen, N. E.; Melle, I.; Westlye, L. T.; Jönsson, E. G.; Andreassen, O. A.; Moberget, T.; Elvsashagen, T.
10.1101/2020.06.06.128926 — neuroscience — Posted on 2020-06-08
3948 Age related defects in NK cell immunity revealed by deep immune profiling of pediatric cancer patients
Syrimi, E.; Khan, N.; Murray, P.; Willcox, C.; Haigh, T.; Willcox, B.; Masand, N.; Zuo, J.; Barone, S.; Irish, J.; Kearns, P.; Taylor, G. S.
10.1101/2020.03.09.983288 — immunology — Posted on 2020-06-08
3950 Molecular mechanism of SARS-Cov-2 components caused ARDS in murine model
Gu, T.; Zhao, S.; Jin, G.; Song, M.; Zhi, Y.; Zhao, R.; Ma, F.; Zheng, Y.; Wang, K.; Liu, H.; Xin, M.; Li, X.; Dong, C. D.; Liu, K.; Dong, Z.
10.1101/2020.06.07.119032 — pathology — Posted on 2020-06-08
3951 Noradrenaline modulates tabula-rasa exploration
Dubois, M.; Habicht, J.; Michely, J.; Moran, R.; Dolan, R.; Hauser, T.
10.1101/2020.02.20.958025 — neuroscience — Posted on 2020-06-08
3952 Multilingual picture naming test for mapping eloquent areas during awake surgeries
Gisbert-Munoz, S.; Quinones, I.; Amoruso, L.; Timofeeva, P.; Geng, S.; Boudelaa, S.; Pomposo, I.; Gil-Robles, S.; Carreiras, M.
10.1101/2020.02.20.957282 — neuroscience — Posted on 2020-06-08
3953 LAMP-Seq: Population-Scale COVID-19 Diagnostics Using Combinatorial Barcoding
Schmid-Burgk, J. L.; Schmithausen, R. M.; Li, D.; Hollstein, R.; Ben-Shmuel, A.; Israeli, O.; Weiss, S.; Paran, N.; Wilbring, G.; Liebing, J.; Feldman, D.; Slabicki, M.; Lippke, B.; Sib, E.; Borrajo, J.; Strecker, J.; Reinhardt, J.; Hoffmann, P.; Cleary, B.; Hoelzel, M.; Noethen, M. M.; Exner, M.; Ludwig, K. U.; Regev, A.; Zhang, F.
10.1101/2020.04.06.025635 — molecular biology — Posted on 2020-06-08
3955 Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients
Andres, C.; Garcia-Cehic, D.; Gregori, J.; Pinana, M.; Rodriguez-Frias, F.; Guerrero, M.; Esperalba, J.; Rando, A.; Goterris, L.; Codina, M. G.; Quer, S.; Martin, M. C.; Campins, M.; Ferrer, R.; Almirante, B.; Esteban, J. I.; Pumarola, T.; Anton, A.; Quer, J.
10.1101/2020.06.03.129585 — microbiology — Posted on 2020-06-08
3956 The Zinc Finger Antiviral Protein restricts SARS-CoV-2
Nchioua, R.; Kmiec, D.; Mueller, J.; Conzelmann, C.; Gross, R.; Swanson, C. M.; Neil, S.; Stenger, S.; Sauter, D.; Muench, J.; Sparrer, K. M.; Kirchhoff, F.
10.1101/2020.06.04.134379 — microbiology — Posted on 2020-06-08
3957 Human H-ferritin presenting RBM of spike glycoprotein as potential vaccine of SARS-CoV-2
Yao, D.; Lao, F.; Zhang, Z.; Liu, Y.; Cheng, J.; Ding, F.; Wang, X.; Xi, L.; Wang, C.; Yan, X.; Zhang, R.; Ouyang, F.; Ding, H.; Ke, T.
10.1101/2020.05.25.115618 — bioengineering — Posted on 2020-06-08
3958 Substrate specificity profiling of SARS-CoV-2 main protease enables design of activity-based probes for patient-sample imaging
Rut, W.; Groborz, K.; Zhang, L.; Sun, X.; Zmudzinski, M.; Pawlik, B.; Mlynarski, W.; Hilgenfeld, R.; Drag, M.
10.1101/2020.03.07.981928 — biochemistry — Posted on 2020-06-08
3961 Is Oculudentavis a bird or even archosaur?
Li, Z.; Wang, W.; Hu, H.; Wang, M.; Yi, H.; Lu, J.
10.1101/2020.03.16.993949 — paleontology — Posted on 2020-06-08
3964 A spatio-temporal mathematical model for the dynamics of paclitaxel in cell monolayers.
Proudfoot, I.; Epemolu, O.; Vallardi, G.; Ptashnyk, M.; Saurin, A. T.; Murray, P. J.; Shishikura, Y.
10.1101/2019.12.12.874032 — cancer biology — Posted on 2020-06-08
3967 Network Analysis and Human Single Cell Brain Transcriptomics Reveal Novel Aspects of Alpha-Synuclein (SNCA) Biology
Teeple, E.; Jindal, K.; Kiragasi, B.; Annaldasula, S.; Byrne, A.; Chai, L.; Sadeghi, M.; Kayatekin, C.; Shankara, S.; Klinger, K.; Sardi, S. P.; Madden, S. L.; Kumar, D.
10.1101/2020.06.05.137166 — neuroscience — Posted on 2020-06-08
3968 Genome-Wide Sequencing as a First-Tier Screening Test for Short Tandem Repeat Expansions
Rajan Babu, I. S.; Peng, J.; Chiu, R.; Study, I.; Study, C.; Mohajeri, A.; Dolzhenko, E.; Eberle, M. A.; Birol, I.; Friedman, J. M.
10.1101/2020.06.06.137356 — genetics — Posted on 2020-06-08
3969 Task-dependent mixed selectivity in the subiculum
Ledergerber, D.; Battistin, C.; Blackstad, J. S.; Gardner, R. J.; Witter, M. P.; Moser, M.-B.; Roudi, Y.; Moser, E. I.
10.1101/2020.06.06.129221 — neuroscience — Posted on 2020-06-08
3970 A mesocosm experiment in ecological physiology: adaptive modulation of energy budget in a hibernating marsupial under chronic caloric restriction
Nespolo, R.; Fonturbel, F. E.; Mejias, C.; Contreras, R.; Gutierrez, P.; Ruiz, J.; Oda, E.; Sabat, P.; Hambly, C.; Speakman, J.; Bozinovic, F.
10.1101/2020.06.05.136028 — ecology — Posted on 2020-06-08
3972 Lentiviral interleukin-10 gene therapy preserves fine motor circuitry and function after a cervical spinal cord injury in male and female mice
Chen, J. Y.; Fu, E. J.; Patel, P. R.; Sawan, H. A.; Moss, K. A.; Hostetler, A. J.; Hocevar, S. E.; Smith, D. R.; Anderson, A. J.; Chestek, C. A.; Shea, L. D.
10.1101/2020.06.05.137257 — neuroscience — Posted on 2020-06-07
3974 A high resolution view of an adolescent flavivirus
Renner, M.; Dejnirattisai, W.; Carrique, L.; Serna Martin, I.; Karia, D.; Ilca, S. L.; Ho, S. F.; Kotecha, A.; Keown, J. R.; Mongkolsapaya, J.; Screaton, G. R.; Grimes, J. M.
10.1101/2020.06.07.138669 — microbiology — Posted on 2020-06-07
3978 Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression
Seruggia, D.; Fernandez, A.; Cantero, M.; Fernandez-Minan, A.; Gomez-Skarmeta, J. L.; Pelczar, P.; Montoliu, L.
10.1101/2020.06.07.139048 — genomics — Posted on 2020-06-07
3979 Phenotype-guided subpopulation identification from single-cell sequencing data
Sun, D.; Guan, X.; Moran, A. E.; Qian, D. Z.; Schedin, P. J.; Adey, A.; Spellman, P. T.; Xia, Z.
10.1101/2020.06.05.137240 — bioinformatics — Posted on 2020-06-07
3980 C3: Connect separate Connected Components to form a succinct disease module
Wang, B.; Hu, J.; Zhang, C.; Zhou, Y.; Yu, L.; Guo, X.; Gao, L.; Chen, Y.
10.1101/2020.06.05.137398 — bioinformatics — Posted on 2020-06-07
3982 Expression and T cell Regulatory Action of the PD-1 Immune Checkpoint in the Ovary and Fallopian Tube
Johnson, J.; Sam, P. K.; Asokan, R.; Llerena Cari, E.; Bales, E. S.; Luu, T.-H.; Perez, L.; Kallen, A. N.; Nel-Themaat, L.; Polotsky, A. J.; Post, M. D.; Orlicky, D. J.; Jordan, K. R.; Bitler, B. G.
10.1101/2020.06.06.138123 — physiology — Posted on 2020-06-07
3987 Ozone nanobubble treatment effectively reduced pathogenic Gram positive and negative bacteria in freshwater and safe for tilapia
Jhunkeaw, C.; Khongcharoen, N.; Rungrueng, N.; Sangpo, P.; Panphut, W.; Thapinta, A.; Senapin, S.; St-Hilaire, S.; Dong, H. T.
10.1101/2020.06.07.138297 — microbiology — Posted on 2020-06-07
3988 IP-MS Analysis of ESX-5 and ESX-1 Substrates Enables Mycobacterial Species Identification
Shu, Q.; Rajagopal, M.; Fan, J.; Zhan, L.; Kong, X.; He, Y.; Rotcheewaphan, S.; Lyon, C. J.; Sha, W.; Zelazny, A. M.; Hu, T.
10.1101/2020.06.07.138784 — microbiology — Posted on 2020-06-07
3989 Characterizing the growing microorganisms at species level in 46 anaerobic digesters at Danish wastewater treatment plants: A six-year survey on microbiome structure and key drivers
Jiang, C.; Peces, M.; Andersen, M. H.; Kucheryavskiy, S.; Nierychlo, M.; Yashiro, E.; Andersen, K. S.; Kirkegaard, R. H.; Hao, L.; Hoegh, J.; Hansen, A. A.; Dueholm, M. S.; Nielsen, P. H.
10.1101/2020.06.07.138891 — microbiology — Posted on 2020-06-07
3990 Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus
Machado, H.; Seif, Y.; Sakoulas, G.; Olson, C. A.; Szubin, R.; Palsson, B.; Nizet, V.; Feist, A. M.
10.1101/2020.06.07.138933 — microbiology — Posted on 2020-06-07
3991 Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers
Peng, D. H.; Rodriguez, B. L.; Diao, L.; Gaudreau, P. O.; Padhye, A.; Ochieng, J. K.; Class, C. A.; Fradette, J. J.; Gibson, L. A.; Chen, L.; Wang, J.; Byers, L. A.; Gibbons, D. L.
10.1101/2020.06.07.136366 — cancer biology — Posted on 2020-06-07
3992 Strain and lineage-level methylome heterogeneity in the multi-drug resistant pathogenic Escherichia coli ST101 clone
Ashcroft, M. M.; Forde, B. M.; Phan, M.-D.; Peters, K. M.; Roberts, L. W.; Chan, K.-G.; Chong, T. M.; Yin, W.-F.; Paterson, D. L.; Walsh, T. R.; Schembri, M. A.; Beatson, S. A.
10.1101/2020.06.07.138552 — genomics — Posted on 2020-06-07
3995 EXOC1 regulates cell morphology of spermatogonia and spermatocytes in mice
Osawa, Y.; Usui, M.; Kuba, Y.; Le, H. T.; Mikami, N.; Nakagawa, T.; Daitoku, Y.; Katok, K.; Shawki, H. H.; Ikeda, Y.; Kuno, A.; Morimoto, K.; Tanimoto, Y.; Dinh, T. T. H.; Murata, K.; Yagami, K.-i.; Ema, M.; Yoshida, S.; Takahashi, S.; Mizuno, S.; Sugiyama, F.
10.1101/2020.06.07.139030 — developmental biology — Posted on 2020-06-07
3996 Molecular mechanism of SARS-Cov-2 components caused ARDS in murine model
Gu, T.; Zhao, S.; Jin, G.; Song, M.; Zhi, Y.; Zhao, R.; Ma, F.; Zheng, Y.; Wang, K.; Liu, H.; Xin, M.; Li, X.; Dong, C. D.; Liu, K.; Dong, Z.
10.1101/2020.06.07.119032 — pathology — Posted on 2020-06-07
3997 Rapid inactivation of SARS-CoV-2 with Deep-UV LED irradiation
Inagaki, H.; Saito, a.; Sugiyama, H.; Okabayashi, T.; Fujimoto, S.
10.1101/2020.06.06.138149 — microbiology — Posted on 2020-06-07
3998 Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system
Cantuti-Castelvetri, L.; Ohja, R.; Pedro, L.; Djannatian, M.; Franz, J.; Kuivanen, S.; Kallio, K.; Kaya, T.; Anastasina, M.; Smura, T.; Levanov, L.; Szirovicza, L.; Tobi, A.; Kallio-Kokko, H.; Osterlund, P.; Joensuu, M.; Meunier, F.; Butcher, S.; Winkler, M.; Mollenhauer, B.; Helenius, A.; Gokce, O.; Teesalu, T.; Hepojoki, J.; Vapalahti, O.; Stadelmann, C.; Balistreri, G.; Simons, M.
10.1101/2020.06.07.137802 — microbiology — Posted on 2020-06-07
3999 Post-capillary venules is the locus for transcytosis of therapeutic nanoparticles to the brain.
Kucharz, K.; Kristensen, K.; Johnsen, K. B.; Lund, M. A.; Lønstrup, M.; Moos, T.; Andresen, T. L.; Lauritzen, M. J.
10.1101/2020.06.05.133819 — neuroscience — Posted on 2020-06-07
4000 Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells
Duong, A.; Evstratova, A.; Sivitilli, A.; Hernandez, J. J.; Gosio, J.; Wahedi, A.; Sondheimer, N.; Wrana, J. L.; Beaulieu, M.; Attisano, L.; Andreazza, A.
10.1101/2020.06.05.135392 — neuroscience — Posted on 2020-06-07
4004 Heat Shock Protein 27 versus Estrogen Therapy for Post-Menopausal Atherosclerosis: Rethinking Mechanisms of Cholesterol Lowering
Maarouf, N.; Chen, Y.-X.; Shi, C.; Deng, J.; Diao, C.; Rosin, M.; Shrivastava, V.; Batulan, Z.; Liu, J.; O'Brien, E. R.
10.1101/2020.06.04.135483 — pathology — Posted on 2020-06-07
4006 Potential for virus endogenization in humans through testicular germ cell infection: the case of HIV
Mahe, D.; Matusali, G.; Deleage, C.; Alvarenga, R.; Satie, A.-P.; Paggliuzza, A.; Mathieu, R.; Lavoue, S.; Jegou, B.; de Franca, L.; Chomont, N.; Houzet, L.; Rolland, A.; Dejucq-Rainsford, N.
10.1101/2020.06.04.135657 — microbiology — Posted on 2020-06-07
4007 Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.
Arias, M.; Pardo, J.; Garzon, M.; Sierra, J. L.; Comas, L.; Santiago, L.; Khaliulina, T.; Uranga, I.; Ramirez, A.; Tapia, E.; Morte, E.; Algarate, S.; Couty, L.; Camerer, E.; Bird, P. I.; Luque, P.; Pano, J. R.; Galvez, E.
10.1101/2020.06.05.135814 — immunology — Posted on 2020-06-07
4010 Genetic screen to saturate guard cell signaling network reveals a role of GDP-L-fucose metabolism in stomatal closure
Waszczak, C.; Vahisalu, T.; Yarmolinsky, D.; Sierla, M.; Zamora, O.; Leal Gavarron, M.; Palorinne, J.; Carter, R.; Pandey, A. K.; Nuhkat, M.; Carmody, M.; Puukko, T.; Sipari, N.; Lamminmäki, A.; Durner, J.; Ernst, D.; Winkler, B.; Paulin, L.; Auvinen, P.; Fleming, A. J.; Salojärvi, J.; Kollist, H.; Kangasjärvi, J.
10.1101/2020.06.04.134353 — plant biology — Posted on 2020-06-07
4011 Proinflammatory S100A9 Regulate Differentiation and Aggregation of Neural Stem Cells
Tian, Y.; Cao, R.; Che, B.; Tang, Y.; Jiang, L.; Bai, Q.; Liu, Y.; Morozova-Roche, L.; Zhang, C.
10.1101/2020.06.06.137745 — cell biology — Posted on 2020-06-07
4013 Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
Cui, X.; Jing, J.; Wu, R.; Cao, Q.; Li, F.; Li, K.; Wang, S.; Yu, L.; Schwartz, G. J.; Shi, H.; Shi, H.; Xue, B.
10.1101/2020.06.06.137273 — physiology — Posted on 2020-06-07
4014 Transgenic goats producing an improved version of cetuximab in milk
Laible, G.; Cole, S.; Brophy, B.; Maclean, P.; Chen, L. H.; Pollock, D. P.; Cavacini, L.; Fournier, N.; De Romeuf, C.; Masiello, N. C.; Gavin, W. G.; Wells, D. N.; Meade, H. M.
10.1101/2020.06.05.137463 — molecular biology — Posted on 2020-06-07
4015 CD47 prevents the elimination of diseased fibroblasts in scleroderma
Lerbs, T.; Cui, L.; King, M.; Chai, T.; Muscat, C.; Shibata, T.; Wernig, G.
10.1101/2020.06.06.138222 — immunology — Posted on 2020-06-07
4018 DUSP7 Regulates the Activity of ERK2 to PromoteProper Chromosome Alignment During Cell Division
Guo, X.; Garcia, Y. A.; Ramirez, I.; Velasquez, E. F.; Gao, L. W.; Gholkar, A. A.; Whitelegge, J. P.; Tofig, B.; Damoiseaux, R.; Torres, J. Z.
10.1101/2020.06.05.137364 — cell biology — Posted on 2020-06-07
4019 Limited inhibition of multiple nodes in a driver network blocks metastasis
Yesilkanal, A. E.; Yang, D.; Tiwari, P.; Sabino, A. U.; Lee, J.; Xie, X.-H.; Sun, S.; Dann, C.; Steinberg, E.; Stuhlmiller, T.; Frankenberger, C.; Goldsmith, E.; Johnson, G. L.; Ramos, A. F.; Rosner, M. R.
10.1101/2020.06.05.137117 — cancer biology — Posted on 2020-06-07
4021 A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of Plasmodium berghei during gametogony and parasite transmission.
Balestra, A. C.; Zeeshan, M.; Rea, E.; Pasquarello, C.; Brusini, L. A.; Mourier, T.; Subudhi, A. K.; Arboit, P.; Klages, N.; Pandey, R.; Brady, D.; Vaughan, S.; Holder, A. A.; Pain, A.; Ferguson, D.; Hainard, A.; Tewari, R.; Brochet, M.
10.1101/2020.02.14.928432 — microbiology — Posted on 2020-06-07
4022 Phylogenetic and evolutionary analysis reveals the recent dominance of ciprofloxacin resistant S. sonnei and local persistence of S. flexneri clones in India
Muthuirulandi Sethuvel, D. P.; Mutreja, A.; Pragasam, A. K.; Vasudevan, K.; Murugan, D.; Anandan, S.; Michael, J. S.; Walia, K.; Balaji, V.
10.1101/2020.06.05.137372 — genomics — Posted on 2020-06-07
4027 Convergent network effects along the axis of gene expression during prostate cancer progression
Charmpi, K.; Guo, T.; Zhong, Q.; Wagner, U.; Sun, R.; Toussaint, N. C.; Fritz, C.; Yuan, C.; Chen, H.; Rupp, N. J.; Christiansen, A.; Rutishauser, D.; Ruschoff, J. H.; Fankhauser, C.; Saba, K.; Poyet, C.; Hermanns, T.; Oehl, K.; Moore, A. L.; Beisel, C.; Calzone, L.; MARTIGNETTI, L.; Zhang, Q.; Zhu, Y. J.; Martinez, M. R.; Manica, M.; Haffner, M. C.; Aebersold, R.; Wild, P. J.; Beyer, A.
10.1101/2020.02.16.950378 — systems biology — Posted on 2020-06-07
4029 Modular slowing of resting-state dynamic Functional Connectivity as a marker of cognitive dysfunction induced by sleep deprivation
Lombardo, D.; Casse-Perrot, C.; Ranjeva, J.-P.; Le Troter, A.; Guye, M.; Wirsich, J.; Payoux, P.; Bartres-Faz, D.; Bordet, R.; Richardson, J. C.; Felician, O.; Jirsa, V.; Blin, O.; Didic, M.; Battaglia, D.
10.1101/2020.01.17.910810 — neuroscience — Posted on 2020-06-07
4030 Single nucleus multi-omics regulatory atlas of the murine pituitary
Ruf-Zamojski, F. M.; Zhang, Z.; Zamojski, M.; Smith, G. R.; Mendelev, N.; Liu, H.; Nudelman, G.; Moriwaki, M.; Pincas, H.; Gomez Castanon, R.; Nair, V. D.; Seenarine, N.; Amper, M. A. S.; Zhou, X.; Ongaro, L.; Toufaily, C.; Schang, G.; Nery, J. R.; Bartlett, A.; Aldridge, A.; Jain, N.; Childs, G. V.; Troyanskaya, O. G.; Ecker, J. R.; Turgeon, J. L.; Welt, C. K.; Bernard, D. J.; Sealfon, S. C.
10.1101/2020.06.06.138024 — cell biology — Posted on 2020-06-07
4031 TMIGD1, a putative tumor suppressor, induces G2-M cell cycle checkpoint arrest in colon cancer cells
De La Cena, K. O.; Ho, R.; Amraei, R.; Woolf, N.; Tashjian, J. Y.; Zhao, Q.; Richards, S.; Walker, J.; Huang, J.; Chitalia, V.; Rahimi, N.
10.1101/2020.06.06.138057 — cancer biology — Posted on 2020-06-07
4033 Salamander-like tail regeneration in the West African lungfish
Verissimo, K. M.; Perez, L. N.; Dragalzew, A. C.; Senevirathne, G.; Darnet, S.; Mendes, W. R.; Neves, C. A.; dos Santos, E. M.; Moraes, C. N.; Elewa, A.; Shubin, N. H.; Froebisch, N. B.; Sousa, J. F.; Schneider, I.
10.1101/2020.02.12.946319 — evolutionary biology — Posted on 2020-06-06
4041 Haplotype tagging reveals parallel formation of hybrid races in two butterfly species
Meier, J. I.; Salazar, P. A.; Kucka, M.; Davies, R. W.; Dreau, A.; Aldas, I.; Box Power, O.; Nadeau, N. J.; Bridle, J. R.; Rolian, C. P.; Barton, N. H.; McMillan, W. O.; Jiggins, C. D.; Chan, Y. F.
10.1101/2020.05.25.113688 — evolutionary biology — Posted on 2020-06-06
4042 Mechanosensory neuron regeneration in adult Drosophila
Fernandez-Hernandez, I.; Marsh, E. B.; Bonaguidi, M. A.
10.1101/812057 — developmental biology — Posted on 2020-06-06
4044 The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome
Duran-Ferrer, M.; Clot, G.; Nadeu, F.; Beekman, R.; Bauman, T.; Nordlund, J.; Marincevic-Zuniga, Y.; Lonnerholm, G.; Rivas, A.; Martin, S.; Ordonez, R.; Castellano, G.; Kulis, M.; Queiros, A.; Seung-Tae, L.; Wiemels, J.; Royo, R.; Puiggros, M.; Lu, J.; Gine, E.; Bea, S.; Jares, P.; Agirre, X.; Prosper, F.; Lopez-Otin, C.; Puente, X. S.; Oakes, C.; Zenz, T.; Delgado, J.; Lopez-Guillermo, A.; Campo, E.; Martin-Subero, J. I.
10.1101/2020.02.06.937383 — cancer biology — Posted on 2020-06-06
4046 Estimating Microbial Interaction Network:Zero-inflated Latent Ising Model Based Approach
Zhou, J.; Viles, W. D.; Lu, B.; Li, Z.; Madan, J. C.; Karagas, M. R.; Gui, J.; Hoen, A. G.
10.1101/2020.06.02.130914 — bioinformatics — Posted on 2020-06-06
4047 Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles
Huang, Y.; Cheng, L.; Turchinovich, A.; Mahairaki, V.; Troncoso, J. C.; Pletnikov, O.; Haughey, N. J.; Vella, L. J.; Hill, A. F.; Zheng, L.; Witwer, K. W.
10.1101/2020.02.10.940999 — neuroscience — Posted on 2020-06-06
4053 Rough and smooth variant Mycobacterium abscessus infections are differentially controlled by host immunity during chronic infection of adult zebrafish
Hortle, E.; Kam, J. Y.; Krogman, E.; Warner, S. E.; Luo, K.; Cheng, T.; Manuneedhi Cholan, P.; Kikuchi, K.; Triccas, J. A.; Britton, W. J.; Johansen, M. D.; Kremer, L.; Oehlers, S. H.
10.1101/856948 — microbiology — Posted on 2020-06-06
4054 Gut microbes and their genes are associated with brain development and cognitive function in healthy children
Bonham, K. S.; Bruchhage, M. M. K.; Rowland, S.; Volpe, L.; Dyer, K.; RESONANCE Consortium, ; D'Sa, V.; Huttenhower, C.; Deoni, S.; Klepac-Ceraj, V.
10.1101/2020.02.13.944181 — microbiology — Posted on 2020-06-06
4055 An innovative approach for HLA typing, molecular tumor testing and the validation of tumor exclusive antigens
Ghosh, M.; Bichmann, L.; Scheid, J.; Gueler, G.; Schuster, H.; Di Marco, M.; Marcu, A.; Beyer, M.; Nelde, A.; Freudenmann, L. K.; Muehlenbruch, L.; Loeffler, M. W.; Kohlbacher, O.; Rammensee, H.-G.; Stevanovic, S.
10.1101/2020.06.05.136754 — immunology — Posted on 2020-06-06
4056 Whole-exome analysis in Parkinson's disease reveals a high burden of ultra-rare variants in early-onset cases
Bustos, B. I.; Krainc, D.; Lubbe, S. J.; International Parkinson's Disease Genomics Consortium,
10.1101/2020.06.06.137299 — genetics — Posted on 2020-06-06
4057 Identifying states of collateral sensitivity during the evolution of therapeutic resistance in Ewings sarcoma
Scarborough, J. A.; McClure, E.; Anderson, P.; Dhawan, A.; Durmaz, A.; Lessnick, S. L.; Hitomi, M.; Scott, J. G.
10.1101/2020.02.11.943936 — evolutionary biology — Posted on 2020-06-06
4058 Identification of rare transient somatic cell states induced by injury and required for whole-body regeneration
Benham-Pyle, B. W.; Brewster, C. E.; Kent, A. M.; Mann, F. G.; Chen, S.; Scott, A. R.; Box, A. C.; Sanchez Alvarado, A.
10.1101/2020.06.04.132753 — developmental biology — Posted on 2020-06-06
4060 Injectable hydrogels for sustained co-delivery of subunit vaccines enhance humoral immunity
Roth, G. A.; Gale, E. C.; Alcantara-Hernandez, M.; Luo, W.; Axpe, E.; Verma, R.; Yin, Q.; Yu, A. C.; Lopez Hernandez, H.; Maikawa, C. L.; Smith, A. A. A.; Davis, M. M.; Pulendran, B.; Idoyaga, J.; Appel, E. A.
10.1101/2020.05.26.117465 — bioengineering — Posted on 2020-06-06
4061 Copy number variants outperform SNPs to reveal genotype-temperature association in a marine species
Dorant, Y.; Cayuela, H.; Wellband, K.; Laporte, M.; Rougemont, Q.; Merot, C.; Normandeau, E.; Rochette, R.; Bernatchez, L.
10.1101/2020.01.28.923490 — genomics — Posted on 2020-06-06
4062 A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome
Gao, F.; Pan, X.; Dodd-Eaton, E. B.; Vera Recio, C. C.; Montierth, M. D.; Bojadzieva, J.; Mai, P. L.; Zelley, K.; Johnson, V. E.; Braun, D.; Nichols, K. E.; Garber, J. E.; Savage, S. A.; Strong, L. C.; Wang, W.
10.1101/2020.02.10.942409 — genetics — Posted on 2020-06-06
4066 AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation
Caratti, G.; Desgeorges, T.; Juban, G.; Koenen, M.; Kozak, B.; Theret, M.; Chazaud, B.; Tuckermann, J. P.; Mounier, R.
10.1101/2020.01.02.892836 — physiology — Posted on 2020-06-06
4067 Stability and similarity of the pediatric connectome as developmental outcomes
Vanderwal, T.; Eilbott, J.; Kelly, C.; Frew, S. R.; Woodward, T. S.; Milham, M.; Castellanos, F. X.
10.1101/828137 — neuroscience — Posted on 2020-06-06
4068 Dual thermal ecotypes co-exist within a nearly genetically-identical population of the unicellular marine cyanobacterium Synechococcus
Kling, J.; Lee, M. D.; Webb, E. A.; Coelho, J. T.; Wilburn, P.; Anderson, S. I.; Zhou, Q.; Wang, C.; Phan, M. D.; Kremer, C. T.; Litchman, E.; Rynearson, T. A.; Hutchins, D. A.
10.1101/2020.05.27.119842 — microbiology — Posted on 2020-06-06
4069 Plasmids shape the diverse accessory resistomes of Escherichia coli ST131
Decano, A. G.; Tran, N.; Al-Foori, H.; Al-Awadi, B.; Leigh Campbell, L.; Ellison, K.; Mirabueno, L. P.; Nelson, M.; Power, S.; Smith, G.; Smyth, C.; Vance, Z.; Rahm, A.; Downing, T.
10.1101/2020.05.07.081380 — genomics — Posted on 2020-06-06
4070 A chromosome-level genome assembly for the Eastern Fence Lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology
Westfall, A. K.; Telemeco, R. S.; Grizante, M. B.; Waits, D. S.; Clark, A. D.; Simpson, D. Y.; Klabacka, R. L.; Sullivan, A. P.; Perry, G. H.; Sears, M. W.; Cox, C. L.; Cox, R. M.; Gifford, M. E.; John-Alder, H. B.; Langkilde, T.; Angilletta, M.; Leache, A.; Tollis, M.; Kusumi, K.; Schwartz, T. S.
10.1101/2020.06.06.138248 — genomics — Posted on 2020-06-06
4075 Characterization of alkaline stress tolerance mechanisms in Lotus forage species modulated by Pantoea eucalypti
CAMPESTRE, M. P.; Castagno, N. L.; Antonelli, C. J.; Maguire, V. G.; Escaray, F. J.; RUIZ, O. A.
10.1101/2020.06.06.138230 — plant biology — Posted on 2020-06-06
4076 DNA methylation across the genome in aged human skeletal muscle tissue and stem cells: The role of HOX genes and physical activity
Turner, D. C.; Gorski, P. P.; Maasar, M. F.; Seaborne, R. A.; Baumert, P.; Brown, A. D.; Kitchen, M. O.; Erskine, R. M.; Dos-Remedios, I.; Voisin, S.; Eynon, N.; Sultanov, R. I.; Borisov, O. V.; Larin, A. K.; Semenova, E. A.; Popov, D. V.; Generozov, E. V.; Stewart, C. E.; Drust, B.; Owens, D. J.; Ahmetov, I. I.; Sharples, A. P.
10.1101/2019.12.27.886135 — physiology — Posted on 2020-06-06
4082 Post-translational control of PlsB is sufficient to coordinate membrane synthesis with growth in Escherichia coli
Noga, M. J.; Buke, F.; van den Broek, N. J.; Imholz, N.; Scherer, N.; Yang, F.; Bokinsky, G.
10.1101/728451 — microbiology — Posted on 2020-06-06
4084 Scc2 and Scc3 promote distinct modes of topological association between cohesin and DNA
Collier, J. E.; Brunet-Roig, M.; Yatskevich, S.; Petela, N. J.; Metson, J.; Voulgaris, M.; Lee, B.-G.; Lowe, J.; Nasmyth, K. A.
10.1101/2020.06.03.132233 — biochemistry — Posted on 2020-06-06
4087 Dynamic Functional Connectivity between Order and Randomness and its Evolution across the Human Adult Lifespan
Battaglia, D.; Thomas, B.; Hansen, E. C.; Lombardo, D.; Chettouf, S.; Daffertshofer, A.; McIntosh, A. R.; Zimmermann, J.; Ritter, P.; Jirsa, V.
10.1101/107243 — neuroscience — Posted on 2020-06-06
4088 Alcohol Drinking Alters Stress Response to Predator Odor via Extended Amygdala Kappa Opioid Receptor Signaling in Male Mice
Hwa, L. S.; Neira, S.; Flanigan, M. E.; Stanhope, C. M.; Pina, M. M.; Pati, D. S.; Hon, O. J.; Yu, W.; Kokush, E.; Calloway, R.; Boyt, K.; Kash, T. L.
10.1101/773481 — neuroscience — Posted on 2020-06-06
4089 RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development
McCusker, P.; Hussain, W.; McVeigh, P.; McCammick, E.; Clarke, N. G.; Robb, E.; McKay, F. M.; Brophy, P. M.; Timson, D. J.; Mousley, A.; Marks, N. J.; Maule, A.
10.1101/2020.06.06.137646 — molecular biology — Posted on 2020-06-06
4091 Population structure of the invasive golden mussel (Limnoperna fortunei) on reservoirs from five Brazilian drainage basins
Rodinho Nunes Ferreira, J. G.; Soares Souza, G. B.; Americo, J. A.; Silva Romao Dumaresq, A.; de Freitas Rebelo, M.
10.1101/2020.05.28.122069 — genetics — Posted on 2020-06-06
4093 A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA
Woodson, M.; Pajak, J.; Zhao, W.; Zhang, W.; Arya, G.; White, M. A.; Jardine, P. J.; Morais, M. C.
10.1101/2020.05.23.112524 — biophysics — Posted on 2020-06-06
4094 Tracking Single Particles for Hours via Continuous DNA-mediated Fluorophore Exchange
Stein, J.; Stehr, F.; Bauer, J.; Niederauer, C.; Jungmann, R.; Ganzinger, K. A.; Schwille, P.
10.1101/2020.05.17.100354 — biophysics — Posted on 2020-06-06
4097 Site-Specific Incorporation of Citrulline into Proteins in Mammalian Cells
Mondal, S.; Wang, S.; Zheng, Y.; Sen, S.; Chatterjee, A.; Thompson, P.
10.1101/2020.06.06.137885 — biochemistry — Posted on 2020-06-06
4100 Distinct medial-temporal lobe mechanisms of encoding and amygdala-mediated memory reinstatement for disgust and fear
Riegel, M.; Wierzba, M.; Wypych, M.; Ritchey, M.; Jednorog, K.; Grabowska, A.; Vuilleumier, P.; Marchewka, A.
10.1101/825844 — neuroscience — Posted on 2020-06-06
4102 Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis
Wu, J.; Song, D.; Li, Z.; Guo, B.; Xiao, Y.; Liu, W.; Liang, L.; Chen, Y.; Feng, C.; Gao, T.; Wang, Z.; Wen, J.; Yang, S.; Liu, P.; Li, Y.; Wang, L.; Wang, Y.; Peng, L.; Hu, Z.; Stacey, G. N.; Feng, G.; Li, W.; Huo, Y.; Jin, R.; Shyh-Chang, N.; Zhou, Q.; Wang, L.; Hu, B.; Dai, H.; Hao, J.
10.1101/2020.04.15.042119 — cell biology — Posted on 2020-06-06
4104 Whole-genome duplication and host genotype affect rhizosphere microbial communities
Bennett Ponsford, J. C.; Hubbard, C. J.; Harrison, J. G.; Maignien, L.; Buerkle, C. A.; Weinig, C.
10.1101/822726 — plant biology — Posted on 2020-06-06
4105 Fitness landscape of a dynamic RNA structure
Soo, V. W.; Swadling, J. B.; Faure, A. J.; Warnecke, T.
10.1101/2020.06.06.130575 — molecular biology — Posted on 2020-06-06
4107 Vaginal microbiota of adolescents and their mothers: A preliminary study of vertical transmission and persistence
Bassis, C. M.; Bullock, K. A.; Sack, D. E.; Saund, K.; Pirani, A.; Snitkin, E. S.; Alaniz, V. I.; Quint, E. H.; Young, V. B.; Bell, J. D.
10.1101/768598 — microbiology — Posted on 2020-06-06
4112 Multi-model evaluation of phenology prediction for wheat in Australia
Wallach, D.; Palosuo, T.; Thorburn, P.; Hochman, Z.; Andrianasolo, F.; Asseng, S.; Basso, B.; Buis, S.; Crout, N.; Dumont, B.; Ferrise, R.; Gaiser, T.; Gayler, S.; Hiremath, S.; Hoek, S.; Horan, H.; Hoogenboom, G.; Huang, M.; Jabloun, M.; Jansson, P.-E.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Luo, Q.; Maestrini, B.; Moriondo, M.; Padovan, G.; Olesen, J. E.; Poyda, A.; Priesack, E.; Pullens, J. W. M.; Qian, B.; Schütze, N.; Shelia, V.; Souissi, A.; Specka, X.; Srivastava, A. K.; Stella, T.; Streck, T.; Trombi, G.; Wallor, E.; Wang, J.; Weber, T. K. D.; Weihermüller, L.
10.1101/2020.06.06.133504 — plant biology — Posted on 2020-06-06
4114 Allergen-induced dendritic cell migration is controlled through Substance P release by sensory neurons
Aderhold, P. A.; Dewan, Z. N. A.; Perner, C.; Flayer, C. H.; Zhu, X.; Voisin, T.; Camire, R. B.; Chiu, I.; Chow, O. A.; Sokol, C. L.
10.1101/2020.06.05.136929 — immunology — Posted on 2020-06-06
4115 Structural basis of ribosomal RNA transcription regulation
Murakami, K.; Shin, Y.; Qayyum, M. Z.; Pupov, D.; Esyunina, D.; Kulbachinskiy, A.
10.1101/2020.06.05.136721 — molecular biology — Posted on 2020-06-06
4117 Diacylglycerol kinase ζ deficiency triggers early signs of aplastic anemia in mice
Martin-Salgado, M.; Andrada, E.; Liebana, R.; Lopez-Santalla, M.; Merida, I.
10.1101/2020.06.05.136390 — immunology — Posted on 2020-06-06
4118 Chromatin and transcriptional response to loss of TBX1 in differentiating mouse P19Cl6 and embryonic stem cells.
Cirino, A.; Aurigemma, I.; Franzese, M.; Lania, G.; Righelli, D.; Ferrentino, R.; Illingworth, E.; Angelini, C.; Baldini, A.
10.1101/2020.06.06.137026 — genomics — Posted on 2020-06-06
4121 Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair
Kathiriya, J. J.; Wang, C.; Brumwell, A.; Cassandras, M.; Le Saux, C.; Wolters, P.; Matthay, M.; Chapman, H. A.; Peng, T.
10.1101/2020.06.06.136713 — cell biology — Posted on 2020-06-06
4122 Partial rescue of neuronal genes deregulated in Cornelia de Lange Syndrome by cohesin
Weiss, F. D.; Calderon, L.; Wang, Y.-F.; Georgieva, R.; Guo, Y.; Cvetesic, N.; Kaur, M.; Dharmalingam, G.; Krantz, I. D.; Lenhard, B.; Fisher, A. G.; Merkenschlager, M.
10.1101/2020.06.06.136432 — cell biology — Posted on 2020-06-06
4123 sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies
Nasirigerdeh, R.; Torkzadehmahani, R.; Matschinske, J.; Frisch, T.; List, M.; Späth, J.; Weiss, S.; Völker, U.; Wenke, N. K.; Kacprowski, T.; Baumbach, J.
10.1101/2020.06.05.136382 — bioinformatics — Posted on 2020-06-06
4124 Monocyte-specific changes in gene expression implicate LACTB2 and PLIN2 in Alzheimer's disease.
Harwood, J. C.; Leonenko, G.; Sims, R.; Escott-Price, V.; Williams, J.; Holmans, P.
10.1101/2020.06.05.136275 — neuroscience — Posted on 2020-06-06
4127 Functional synchronization between hippocampal sEEG, parietal ECoG and scalp EEG during a verbal working memory task.
Dimakopoulos, V. S.; Boran, E.; Hilfiker, P.; Stieglitz, L.; Grunwald, T.; Megevand, P.; Sarnthein, J.
10.1101/2020.06.05.136515 — neuroscience — Posted on 2020-06-06
4128 Cross-neutralization antibodies against SARS-CoV-2 and RBD mutations from convalescent patient antibody libraries
Lou, Y.; Zhao, W.; Wei, H.; Chu, M.; Chao, R.; Yao, H.; Su, J.; Li, Y.; Li, X.; Cao, Y.; Feng, Y.; Wang, P.; Xia, Y.; Shang, Y.; Li, F.; Ge, P.; Zhang, X.; Gao, W.; Du, B.; Liang, T.; Qiu, Y.; Liu, M.
10.1101/2020.06.06.137513 — immunology — Posted on 2020-06-06
4131 Synthetic Antibodies neutralize SARS-CoV-2 infection of mammalian cells
Miersch, S.; Ustav, M.; Li, Z.; Case, J. B.; Ganaie, S.; Matusali, G.; Colavita, F.; Lapa, D.; Capobianchi, M. R.; Novelli, G.; Gupta, J. B.; Jain, S.; Pandolfi, P. P.; Diamond, M. S.; Amarasinghe, G.; Rini, J. M.; Sidhu, S. S.
10.1101/2020.06.05.137349 — biochemistry — Posted on 2020-06-06
4135 Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth
Tarca, A.; Pataki, B. A.; Romero, R.; Sirota, M.; Guan, Y.; Kutum, R.; Gomez-Lopez, N.; Done, B.; Bhatti, G.; Yu, T.; Andreoletti, G.; Chaiworapongsa, T.; Consortium, T. D. P. B. P. C.; Hassan, S. S.; Hsu, C.-D.; Aghaeepour, N.; Stolovitzky, G. A.; Csabai, I.; Costello, J. C.
10.1101/2020.06.05.130971 — bioinformatics — Posted on 2020-06-06
4137 MCL1 dependence across MDS subtypes and dual inhibition of MCL1 and BCL2 in MISTRG6 mice
Fischer, M. A.; Song, Y.; Gbyli, R.; Arrate, M. P.; Villaume, M. T.; Childress, M. A.; Smith, B. N.; Stricker, T. P.; Halene, S.; Savona, M. R.
10.1101/2020.06.05.133090 — cancer biology — Posted on 2020-06-06
4138 Paternal obesity and epigenetic inheritance of breast cancer: The role of systemic effects and transmission to the second generation
Fontelles, C. C.; da Cruz, R. S.; Gonsiewski, A. K.; Barin, E.; Tekmen, V.; Jin, L.; Cruz, M. I.; Loudig, O.; Warri, A.; de Assis, S.
10.1101/2020.06.05.136234 — cancer biology — Posted on 2020-06-06
4140 A partial C4 photosynthetic biochemical pathway in rice
Lin, H.-C.; Arrivault, S.; Coe, R. A.; Karki, S.; Covshoff, S.; Bagunu, E.; Lunn, J. E.; Stitt, M.; Furbank, R. T.; Hibberd, J. M.; Quick, W. P.
10.1101/2020.06.03.133058 — plant biology — Posted on 2020-06-06
4141 UBR5 knockdown in human myotubes in-vitro and mouse skeletal muscle tissue in-vivo determines its pertinent role in anabolism and hypertrophy
Turner, D. C.; Hughes, D. C.; Baehr, L. M.; Seaborne, R. A.; Viggars, M.; Jarvis, J. C.; Gorski, P. P.; Stewart, C. E.; Owens, D. J.; Bodine, S. C.; Sharples, A. P.
10.1101/2020.06.05.116145 — physiology — Posted on 2020-06-06
4144 Local sleep during mind-wandering enhances processes of spatial attention allocation
Wienke, C.; Bartsch, M. V.; Vogelgesang, L.; Reichert, C.; Hinrichs, H.; Heinze, H.-J.; Duerschmid, S.
10.1101/2020.06.05.136374 — neuroscience — Posted on 2020-06-06
4145 Hippocampal and striatal responses during motor learning are modulated byprefrontal cortex stimulation
Gann, M. A.; King, B. R.; Dolfen, N.; Veldman, M. P.; Chan, K. L.; Puts, N. A. J.; Edden, R. A. E.; Davare, M.; Swinnen, S. P.; Mantini, D.; Robertson, E. M.; Albouy, G.
10.1101/2020.06.05.136531 — neuroscience — Posted on 2020-06-06
4146 Anesthetics uniquely decorrelate hippocampal network activity, alter spine dynamics and affect memory consolidation
Yang, W.; Chini, M.; Poepplau, J. A.; Formozov, A.; Piechocinski, P.; Rais, C.; Morellini, F.; Sporns, O.; Hanganu-Opatz, I. L.; Wiegert, J. S.
10.1101/2020.06.05.135905 — neuroscience — Posted on 2020-06-06
4147 Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain
Chantranupong, L.; Saulnier, J. L.; Wang, W.; Jones, D. R.; Pacold, M.; Sabatini, B.
10.1101/2020.06.05.136093 — neuroscience — Posted on 2020-06-06
4149 Robust T-cell signaling triggered on soft polydimethylsiloxane-supported lipid-bilayers
Lippert, A. H.; Dimov, I. B.; Winkel, A.; McColl, J.; Humphrey, J.; Chen, K. Y.; Santos, A. M.; Jenkins, E.; Franze, K.; Davis, S.; Klenerman, D.
10.1101/2020.06.05.134684 — biophysics — Posted on 2020-06-06
4151 The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure
Sun, Y.; Zhao, K.; Xia, W.; Gu, J.; Ma, Y.; Gui, X.; Zhang, X.; Fang, Y.; Sun, B.; Liu, C.; Li, D.
10.1101/2020.06.05.135673 — biophysics — Posted on 2020-06-06
4152 Novel allergen discovery through comprehensive de novo transcriptomic analyses of 5 shrimp species
Karnaneedi, S.; Huerlimann, R.; Johnston, E. B.; Nugraha, R.; Ruethers, T.; Taki, A. C.; Kamath, S. D.; Wade, N. M.; Jerry, D. R.; Lopata, A. L.
10.1101/2020.06.05.135731 — bioinformatics — Posted on 2020-06-06
4155 In vivo fluorescence imaging with a flat, lensless microscope
Adams, J. K.; Boominathan, V.; Gao, S.; Rodriguez, A. V.; Yan, D.; Kemere, C.; Veeraraghavan, A.; Robinson, J. T.
10.1101/2020.06.04.135236 — neuroscience — Posted on 2020-06-06
4156 Compensatory hippocampal neurogenesis in the absence of cognitive impairment following experimental hippocampectomy in adult rats
Cardoso, G. T.; Gomes-Leal, W.; Franco, E. C.; Gama, J. S.; Gomes, F. L.; Brino, A. L. F.; Lima, S. M. A.
10.1101/2020.06.04.135350 — neuroscience — Posted on 2020-06-06
4157 AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia
Poh, L.; Fann, D.; Wong, P.; Lim, H. M.; Foo, S. L.; Kang, S.-W.; Rajeev, V.; Selvaraji, S.; Vinaya, R. I.; Parathy, N.; Khan, M. B.; Jo, D.-G.; Drummond, G. R.; Sobey, C. G.; Lai, M. K. P.; Chen, C. L.-H.; Lim, L. H. K.; Arumugam, T. V.
10.1101/2020.06.05.135228 — neuroscience — Posted on 2020-06-06
4158 Activation of the myeloid checkpoint inhibitor LILRB3 (ILT5) elicits profound immununomodulation
Yeboah, M.; Papagregoriou, C.; Jones, D. C.; Chan, H. T. C.; Hu, G.; McPartlan, J. S.; Schiott, T.; Mattson, U.; Mockridge, C. I.; Tornberg, U.-C.; Hambe, B.; Ljungars, A.; Mattsson, M.; Tews, I.; Thirdborough, S. M.; Trowsdale, J.; Frendeus, B.; Chen, J.; Cragg, M. S.; Roghanian, A.
10.1101/2020.06.04.135400 — immunology — Posted on 2020-06-06
4159 Spatial point locations explain a range of social network positions in a wild ungulate
Albery, G. F.; Morris, A.; Morris, S.; Pemberton, J. M.; Clutton-Brock, T. H.; Nussey, D. H.; Firth, J. A.
10.1101/2020.06.04.135467 — ecology — Posted on 2020-06-06
4160 Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis
Wu, S. Z.; Roden, D. L.; Al-Eryani, G.; Bartonicek, N.; Harvey, K.; Cazet, A. S.; Chan, C.-L.; Junankar, S.; Hui, M. N.; Millar, E.; Beretov, J.; Horvath, L.; Joshua, A. M.; Stricker, P.; Wilmott, J. S.; Quek, C.; Long, G. V.; Scolyer, R. A.; Yeung, B. Z.; Segara, D.; Mak, C.; Warrier, S.; Powell, J.; O'Toole, S.; Lim, E.; Swarbrick, A.
10.1101/2020.06.04.135277 — cancer biology — Posted on 2020-06-06
4161 Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer
Wu, S. Z.; Roden, D. L.; Wang, C.; Holliday, H.; Harvey, K.; Cazet, A. S.; Murphy, K. J.; Pereira, B.; Al-Eryani, G.; Bartonicek, N.; Hou, R.; Torpy, J. R.; Junankar, S.; Chan, C.-L.; Lam, E.; Hui, M. N.; Gluch, L.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Mak, C.; Cooper, C.; Warrier, S.; Forrest, A.; Powell, J.; O'Toole, S.; Cox, T. R.; Timpson, P.; Lim, E.; Liu, X. S.; Swarbrick, A.
10.1101/2020.06.04.135327 — cancer biology — Posted on 2020-06-06
4162 Induction of intracellular wild-type p53 amyloids leading to cellular transformation and tumor formation in mice
Navalkar, A.; Pandey, S.; Singh, N.; Dey, A. K.; Saha, S.; Patel, K.; Mohanty, B. K.; Jadhav, S.; Chaudhari, P.; Maiti, T. K.; Maji, S. K.
10.1101/2020.06.04.133124 — cancer biology — Posted on 2020-06-06
4165 Introgression from Oryza meridionalis into domesticated rice Oryza sativa results in shoot-based iron tolerance
Wairich, A.; de Oliveira, B. H. N.; Wu, L.-B.; Murugaiyan, V.; Margis, M. P.; Fett, J. P.; Ricachenevsky, F.; Frei, M.
10.1101/2020.06.05.135947 — plant biology — Posted on 2020-06-06
4166 Cold induced chromatin compaction and nuclear retention of clock mRNAs resets the circadian rhythm
Fischl, H.; McManus, D.; Oldenkamp, R.; Schermelleh, L.; Mellor, J.; Jagannath, A.; Furger, A.
10.1101/2020.06.05.127290 — molecular biology — Posted on 2020-06-06
4167 Pan-Cancer analysis of somatic mutations in miRNA genes
Urbanek-Trzeciak, M. O.; Galka-Marciniak, P.; Nawrocka, P. M.; Kowal, E.; Szwec, S.; Giefing, M.; Kozlowski, P.
10.1101/2020.06.05.136036 — genomics — Posted on 2020-06-06
4168 Ancient viral genomes reveal introduction of HBV and B19V to Mexico during the transatlantic slave trade.
Guzman-Solis, A. A.; Blanco-Melo, D.; Villa-Islas, V.; Bravo-Lopez, M. J.; Sandoval-Velasco, M.; Wesp, J. K.; Gomez-Valdes, J. A.; Moreno-Cabrera, M. d. l. L.; Meraz-Moreno, A.; Solis-Pichardo, G.; Schaaf, P.; tenOever, B. R.; Avila-Arcos, M. C.
10.1101/2020.06.05.137083 — genomics — Posted on 2020-06-06
4170 Improved diagnosis of viral encephalitis in adult and pediatric hematological patients using viral metagenomics
Carbo, E. C.; Buddingh, E. P.; Karelioti, E.; Sidorov, I.; Feltkamp, M. C.; Von dem Borne, P. A.; Verschuuren, J. J.; Kroes, L. C.; Claas, E. C.; de Vries, J. J.
10.1101/2020.06.05.136317 — genomics — Posted on 2020-06-06
4172 Ontogeny, species identity and environment dominate microbiome dynamics in wild populations of kissing bugs (Triatominae)
Brown, J. J.; Rodriguez-Ruano, S. M.; Poosakkannu, A.; Batani, G.; Schmidt, J. O.; Roachell, W.; Zima, J.; Hypsa, V.; Novakova, E.
10.1101/2020.06.05.135871 — ecology — Posted on 2020-06-06
4173 A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis
Contreras, X.; Davaatseren, A.; Amberg, N.; Hansen, A. H.; Sonntag, J.; Andersen, L.; Bernthaler, T.; Heger, A.; Johnson, R.; Schwarz, L. A.; Luo, L.; Ruelicke, T.; Hippenmeyer, S.
10.1101/2020.06.05.136192 — developmental biology — Posted on 2020-06-06
4174 CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells
Darvish Shafighi, S.; Kiełbasa, S. M.; Sepulveda-Yanez, J.; Monajemi, R.; Cats, D.; Mei, H.; Menafra, R.; Kloet, S.; Veelken, H.; Bergen, C. A. M. v.; Szczurek, E.
10.1101/2020.06.05.134452 — cancer biology — Posted on 2020-06-06
4175 Mis-annotated multi nucleotide variants in public cancer genomics datasets can lead to inaccurate mutation calls with significant implications
Srinivasan, S.; Kalinava, N.; Aldana, R.; Li, Z.; Van Hagen, S.; Rodenburg, S. Y. A.; Wind-Rotolo, M.; Sasson, A. S.; Tang, H.; Qian, X.; Kirov, S.
10.1101/2020.06.05.136549 — genomics — Posted on 2020-06-06
4177 Trans control of cardiac mRNA translation in a protein length-dependent fashion
Witte, F.; Ruiz-Orera, J.; Ciolli Mattioli, C.; Blachut, S.; Adami, E.; Schulz, J. F.; Schneider-Lunitz, V.; Hummel, O.; Patone, G.; Mucke, M. B.; Silhavy, J.; Heinig, M.; Bottolo, L.; Sanchis, D.; Vingron, M.; Chekulaeva, M.; Pravenec, M.; Hubner, N.; van Heesch, S.
10.1101/2020.06.05.133298 — genetics — Posted on 2020-06-06
4179 YAP and β-catenin co-operate to drive oncogenesis in basal breast cancer
Quinn, H.; Koren, E.; Vogel, R.; Popp, O.; Mertins, P.; Messerschmidt, C.; Marangoni, E.; Fuchs, Y.; Birchmeier, W.
10.1101/2020.06.05.115881 — cancer biology — Posted on 2020-06-06
4180 The Mechanism of Vesicle Solubilization by the Detergent Sodium Dodecyl Sulfate
Juan-Colas, J.; Dresser, L.; Morris, K.; Lagadou, H.; Ward, R. H.; Burns, A.; Tear, S.; Johnson, S.; Leake, M. C.; Quinn, S. D.
10.1101/2020.06.05.133868 — biophysics — Posted on 2020-06-06
4181 Post-Translational Modifications Soften Intermediate Filaments
Kraxner, J.; Lorenz, C.; Menzel, J.; Parfentev, I.; Silbern, I.; Urlaub, H.; Schwappach, B.; Koester, S.
10.1101/2020.06.05.135780 — biophysics — Posted on 2020-06-06
4183 CDK4/6 inhibition promotes senescent states with restricted secretory phenotype and reduced toxicity
Wang, B.; Brandenburg, S.; Hernandez-Segura, A.; van Vliet, T.; Jongbloed, E. M.; Wilting, S. M.; Ohtani, N.; Jager, A.; Demaria, M.
10.1101/2020.06.05.135715 — cell biology — Posted on 2020-06-05
4184 Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis
Garrido, D.; Bourouh, M.; Bonneil, E.; Thibault, P.; Swan, A.; Archambault, V.
10.1101/2020.06.05.136291 — cell biology — Posted on 2020-06-05
4185 Cholesterol rich, highly phase separated, naked mole-rat brain lipids are exquisitely sensitive to amyloid induced membrane damage
FRANKEL, D.; St John Smith, E.; Rankin, K.; Cenac, N.; Davies, M.; Kumita, J. R.; Vendruscolo, M.; Kulaberoglu, Y.; Urriola Munoz, P.; Bertrand-michel, J.; Preet, S.; Smith, A.; Bhushan, B.
10.1101/2020.06.05.134973 — biophysics — Posted on 2020-06-05
4187 Cycling cancer persister cells arise from lineages with distinct transcriptional and metabolic programs
Oren, Y.; Tsabar, M.; Cabanos, H. F.; Cuoco, M. S.; Zaganjor, E.; Thakore, P. I.; Tabaka, M.; Fulco, C. P.; Hurvitz, S. A.; Slamon, D. J.; Lahav, G.; Hata, A.; Brugge, J. S.; Regev, A.
10.1101/2020.06.05.136358 — cancer biology — Posted on 2020-06-05
4188 Molecular basis for recognition of Listeria cell wall teichoic acid by the pseudo-symmetric SH3b-like repeats of a bacteriophage endolysin
Shen, Y.; Kalograiaki, I.; Prunotto, A.; Dunne, M.; Boulos, S.; Taylor, N. M. I.; Sumrall, E. T.; Eugster, M. R.; Martin, R.; Rodero, A. J.; Gerber, B.; Leiman, P. G.; Menendez, M. F.; Peraro, M. D.; Canada, F. J.; Martin, L. J.
10.1101/2020.06.05.136911 — biophysics — Posted on 2020-06-05
4192 Viral-mediated ubiquitination impacts interactions of host proteins with viral RNA and promotes viral RNA processing
Herrmann, C.; Dybas, J. M.; Liddle, J. C.; Price, A. M.; Hayer, K. E.; Lauman, R.; Purman, C. E.; Charman, M.; Kim, E. T.; Garcia, B. A.; Weitzman, M. D.
10.1101/2020.06.05.136671 — microbiology — Posted on 2020-06-05
4193 Frequent loss-of-heterozygosity in CRISPR-Cas9-edited early human embryos
Alanis-Lobato, G.; Zohren, J.; McCarthy, A.; Fogarty, N. M. E.; Kubikova, N.; Hardman, E.; Greco, M.; Wells, D.; Turner, J. M. A.; Niakan, K.
10.1101/2020.06.05.135913 — developmental biology — Posted on 2020-06-05
4194 CryoEM Structure of Drosophila Flight Muscle Thick Filaments at 7A Resolution
Daneshparvar, N.; Taylor, D. W.; O'Leary, T. S.; Rahmani, H.; Abbasi Yeganeh, F.; Previs, M. J.; Taylor, K. A.
10.1101/2020.06.05.136580 — biophysics — Posted on 2020-06-05
4196 Iron Supplementation Eliminates Antagonistic Interactions Between Root Associated Bacteria
Eng, T. T.; Herbert, R. A.; Martinez, U.; Wang, B.; Chen, J.; Brown, J. B.; Deutschbauer, A.; Bissell, M.; Mortimer, J.; Mukhopadhyay, A.
10.1101/2020.06.05.132704 — microbiology — Posted on 2020-06-05
4197 Large scale metagenome assembly reveals novel animal-associated microbial genomes, biosynthetic gene clusters, and other genetic diversity
Youngblut, N. D.; de la Cuesta-Zuluaga, J.; Reischer, G. H.; Dauser, S.; Schuster, N.; Walzer, C.; Stalder, G.; Farnleitner, A.; Ley, R. E.
10.1101/2020.06.05.135962 — microbiology — Posted on 2020-06-05
4199 Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box
Reader, J.; van der Watt, M. E.; Taylor, D.; Le Manach, C.; Mittal, N.; Ottilie, S.; Theron, A.; Moyo, P.; Erlank, E.; Nardini, L.; Venter, N.; Lauterbach, S.; Bezuidenhout, B.; Horatscheck, A.; van Heerden, A.; Boyle, G. A.; Calvo, D.; Mancama, D.; Coetzer, T. L.; Winzeler, E. A.; Duffy, J.; Koekemoer, L. L.; Basarab, G.; Chibale, K.; Birkholtz, L.-M.
10.1101/2020.06.05.133405 — microbiology — Posted on 2020-06-05
4200 Cytoplasmic CPSF6 regulates HIV-1 capsid trafficking and infection in a cyclophilin A-dependent manner
Zhong, Z.; Ning, J.; Boggs, E. A.; Jang, S.; Wallace, C.; Telmer, C.; Bruchez, M.; Ahn, J.; Engelman, A.; zhang, p.; Watkins, S. C.; Ambrose, Z.
10.1101/2020.06.05.136697 — microbiology — Posted on 2020-06-05
4202 HIF2α is a Direct Regulator of Neutrophil Motility
Sormendi, S.; Deygas, M.; Sinha, A.; Krueger, A.; Kourtzelis, I.; Le Lay, G.; Bernard, M.; Saez, P.; Gerlach, M.; Franke, K.; Meneses, A.; Kraeter, M.; Palladini, A.; Guck, J.; Coskun, U.; Chavakis, T.; Vargas, P.; Wielockx, B.
10.1101/2020.06.05.137133 — immunology — Posted on 2020-06-05
4203 Aging imparts cell-autonomous dysfunction to regulatory T cells during recovery from influenza pneumonia
Morales-Nebreda, L.; Helmin, K. A.; Markov, N. S.; Piseaux, R.; Torres Acosta, M. A.; Abdala-Valencia, H.; Politanska, Y.; Singer, B. D.
10.1101/2020.06.05.135194 — immunology — Posted on 2020-06-05
4205 No evidence for insecticide resistance in a homogenous population of Aedes albopictus in Mecklenburg County, North Carolina
Mundis, S. J.; Hamerlinck, G.; Stone, E.; Whiteman, A.; Delmelle, E.; Rapp, T.; Dulin, M.; Ryan, S. J.
10.1101/2020.06.05.136135 — ecology — Posted on 2020-06-05
4210 Insights on cross-species transmission of SARS-CoV-2 from structural modeling
Rodrigues, J. P.; Barrera-Vilarmau, S.; Teixeira, J. M.; Seckel, E.; Kastritis, P. L.; Levitt, M.
10.1101/2020.06.05.136861 — bioinformatics — Posted on 2020-06-05
4212 SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts.
Moustaqil, M.; Ollivier, E.; Chiu, H.-P.; Rudolffi-Soto, P.; Van Tol, S.; Stevens, C.; Bhumkar, A.; Hunter, D. J. B.; Freiberg, A. N.; Jacques, D.; Lee, B.; Sierecki, E.; Gambin, Y.
10.1101/2020.06.05.135699 — molecular biology — Posted on 2020-06-05
4213 SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species
Singh, D. K.; Ganatra, S. R.; Singh, B.; Cole, J.; Alfson, K. J.; Clemmons, E.; Gazi, M.; Gonzalez, O.; Escabedo, R.; Lee, T.-H.; Chatterjee, A.; Goez-Gazi, Y.; Sharan, R.; Thippeshappa, R.; Gough, M.; Alvarez, C.; Blakely, A.; Ferdin, J.; Bartley, C.; Staples, H.; Parodi, L.; Callery, J.; Mannino, A.; Klaffke, B.; Escareno, P.; Platt, R. N.; Hodara, V.; Scordo, J.; Oyejide, A.; Ajithdoss, D. K.; Copin, R.; Baum, A.; Kyratsous, C.; Alvarez, X.; Rosa, B.; Ahmed, M.; Goodroe, A.; Dutton, J.; Hall-Ursone, S.; Frost, P.; Voges, A. K.; Ross, C. N.; Sayers, K.; Chen, C.; Hallam, C.; Khader, S. A.; M
10.1101/2020.06.05.136481 — immunology — Posted on 2020-06-05
4214 SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
Bertoglio, F.; Meier, D.; Langreder, N.; Steinke, S.; Rand, U.; Simonelli, L.; Heine, P. A.; Ballmann, R.; Schneider, K.-T.; Roth, K. D. R.; Ruschig, M.; Riese, P.; Eschke, K.; Kim, Y.; Schaeckermann, D.; Pedotti, M.; Kuhn, P.; Zock-Emmenthal, S.; Woehrle, J.; Becker, M.; Grashoff, M.; Wenzel, E. V.; Russo, G.; Kroeger, A.; Brunotte, L.; Ludwig, S.; Fuehner, V.; Kraemer, S. D.; Duebel, S.; Varani, L.; Roth, G.; Cicin-Sain, L.; Schubert, M.; Hust, M.
10.1101/2020.06.05.135921 — biochemistry — Posted on 2020-06-05
4216 Germline APOBEC3B deletion in Asian women increases somatic hypermutation in breast cancer that is associated with Her2 subtype, PIK3CA mutations, immune activation, and increased survival
Pan, J.-W.; Zabidi, M. M. A.; Chong, B.-K.; Meng, M.-Y.; Ng, P.-S.; Hasan, S. N.; Sandey, B.; Bahnu, S.; Rajadurai, P.; Yip, C.-H.; Rueda, O. M.; Caldas, C.; Chin, S.-F.; Teo, S.-H.
10.1101/2020.06.04.135251 — cancer biology — Posted on 2020-06-05
4218 Orphan nuclear receptor COUP-TFII drives the myofibroblast metabolic shift leading to fibrosis
Li, L.; Galichon, P.; Xiao, X.; Figueroa-Ramirez, A. C.; Tamayo, D.; Lee, J. J.; Kalocsay, M.; Gonzalez-Sanchez, D.; Chancay, M. S.; McCracken, K.; Lemos, D.; Lee, N.; Ichimura, T.; Mori, Y.; Valerius, M. T.; Sun, X.; Edelman, E. R.; Bonventre, J. V.
10.1101/2020.06.05.135889 — cell biology — Posted on 2020-06-05
4222 A generative modeling approach for interpreting population-level variability in brain structure
Liu, R.; Subakan, C.; Balwani, A. H.; Whitesell, J. D.; Harris, J. A.; Koyejo, S.; Dyer, E.
10.1101/2020.06.04.134635 — neuroscience — Posted on 2020-06-05
4224 Bioaugmented sand filter columns provide stable removal of pesticide residue from membrane retentate
Ellegaard-Jensen, L.; Schostag, M.; Fini, M. N.; Badawi, N.; Gobbi, A.; Aamand, J.; Hansen, L. H.
10.1101/2020.06.04.135582 — microbiology — Posted on 2020-06-05
4228 Distinct genetic pathways define pre-leukemic and compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
Kennedy, A. L.; Myers, K. C.; Bowman, J.; Gibson, C. J.; Camarda, N. D.; Furutani, E. M.; Muscato, G. M.; Klein, R. H.; Ballotti, K.; Liu, S.; Harris, C. E.; Galvin, A.; Malsch, M.; Dale, D.; Gansner, J. M.; Nakano, T. A.; Bertuch, A.; Vlachos, A.; Lipton, J. M.; Castillo, P.; Connelly, J.; Churpek, J.; Edwards, J. R.; Hijiya, N.; Ho, R. H.; Hofmann, I.; Huang, J. N.; Keel, S.; Lamble, A.; Lau, B. W.; Norkin, M.; Stieglitz, E.; Stock, W.; Walkovich, K.; Boettcher, S.; Brendel, C.; Fleming, M. D.; Davies, S. M.; Weller, E. A.; Bahl, C.; Carter, S. L.; Shimamura, A.; Lindsley, R. C.
10.1101/2020.06.04.134692 — cancer biology — Posted on 2020-06-05
4229 Structural insight into outer membrane asymmetry maintenance of Gram-negative bacteria by the phospholipid transporter MlaFEDB
Tang, X.; Chang, S.; Qiao, W.; Luo, Q.; Chen, Y.; Jia, Z.; Coleman, J.; Zhang, K.; Wang, T.; Zhang, Z.; Zhang, C.; Zhu, X.; Wei, X.; Dong, C.; Zhang, X.; Dong, H.
10.1101/2020.06.04.133611 — biochemistry — Posted on 2020-06-05
4235 Phenotype Spectrum reflects Synergies among the Cell Architecture over Stages of the Cell Cycle
Lan, T.; Yu, M.; Chen, W.; Yin, J.; Chang, H.-T.; Tang, S.; Zhao, Y.; Svrononos, S. A.; Wong, S. W. K.; Tseng, Y.
10.1101/2020.06.05.135723 — cell biology — Posted on 2020-06-05
4236 Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel
Xiong, C.; Chua, K. C.; Stage, T. B.; Kim, J.; Altman-Merino, A.; Chan, D.; Saraf, K.; Ferracini, A. C.; Fattahi, F.; Kroetz, D. L.
10.1101/2020.06.04.134262 — pharmacology and toxicology — Posted on 2020-06-05
4239 An OpenData portal to share COVID-19 drug repurposing data in real time
Brimacombe, K. R.; Zhao, T.; Eastman, R. T.; Hu, X.; Wang, K.; Backus, M.; Baljinnyam, B.; Chen, C. Z.; Chen, L.; Eicher, T.; Ferrer, M.; Fu, Y.; Gorshkov, K.; Guo, H.; Hanson, Q. M.; Itkin, Z.; Kales, S. C.; Klumpp-Thomas, C.; Lee, E. M.; Michael, S.; Mierzwa, T.; Patt, A.; Pradhan, M.; Renn, A.; Shinn, P.; Shrimp, J. H.; Viraktamath, A.; Wilson, K. M.; Xu, M.; Zakharov, A. V.; Zhu, W.; Zheng, W.; Simeonov, A.; Mathe, E. A.; Lo, D. C.; Hall, M. D.; Shen, M.
10.1101/2020.06.04.135046 — microbiology — Posted on 2020-06-05
4242 Heparanase promotes Syndecan-1 expression to mediate fibrillar collagen and mammographic density in human breast tissue cultured ex vivo.
Huang, X.; Reye, G.; Momot, K. I.; Blick, T.; Lloyd, T.; Tilley, W. D.; Hickey, T. E.; Snell, C. E.; Okolicsanyi, R. K.; Haupt, L. M.; Ferro, V.; Thompson, E. W.; Hugo, H. J.
10.1101/2020.06.04.135202 — cancer biology — Posted on 2020-06-05
4243 Age-induced methylmalonic acid accumulation promotes tumor progression and aggressiveness
Gomes, A. P.; Ilter, D.; Low, V.; Endress, J.; Fernandez-Garcia, J.; Rosenzweig, A.; Schild, T.; Broekaert, D.; Ahmed, A.; Planque, M.; Elia, I.; Han, J.; Kinzig, C.; Mullarky, E.; Mutvei, A.; Asara, J. M.; deCabo, R.; Cantley, L. C.; Dephoure, N.; Fendt, S.-M.; Blenis, J.
10.1101/2020.06.04.135087 — cancer biology — Posted on 2020-06-05
4245 The framework of lncRNAs and genes at early pollen developmental stage in a PTGMS wheat line
Bai, J.-f.; Liu, Z.-h.; Wang, Y.-k.; Guo, H.-y.; Guo, L.-p.; Tan, Z.-g.; Yuan, S.-h.; Li, Y.-m.; Li, T.-t.; Duan, W.-j.; Yue, J.-r.; Zhang, F. t.; Zhao, C.-P.; Zhang, L.-P.
10.1101/2020.06.05.136606 — plant biology — Posted on 2020-06-05
4248 The unconventional cytoplasmic sensing mechanism for ethanol chemotaxis in Bacillus subtilis
Tohidifar, P.; Bodhankar, G. A.; Pei, S.; Cassidy, C. K.; Walukiewicz, H. E.; Orodal, G. W.; Stansfeld, P. J.; Rao, C.
10.1101/2020.06.04.135640 — microbiology — Posted on 2020-06-05
4249 Rewiring PBMC responses to prevent CHIKV infection-specific monocyte subset redistribution and cytokine responses
Aguilar Briseno, J. A.; Ruiz Silva, M.; Moser, J.; Pauzuolis, M.; Smit, J. M.; Rodenhuis-Zybert, I. A.
10.1101/2020.06.04.132340 — immunology — Posted on 2020-06-05
4250 A novel in-cell ELISA assay allows rapid and automated quantification of SARS-CoV-2 to analyse neutralizing antibodies and antiviral compounds
Schoeler, L.; Le-Trilling, V. T. K.; Eilbrecht, M.; Mennerich, D.; Anastasiou, O. E.; Krawczyk, A.; Herrmann, A.; Dittmer, U.; Trilling, M.
10.1101/2020.06.05.135806 — immunology — Posted on 2020-06-05
4253 Adipose Tissue is a Critical Regulator of Osteoarthritis
Collins, K. H.; Lenz, K. L.; Pollitt, E. N.; Ferguson, D.; Hutson, I.; Springer, L. E.; Oestreich, A. K.; Tang, R.; Choi, Y.-R.; Meyer, G. A.; Teitelbaum, S. L.; Pham, C. T. N.; Harris, C. A.; Guilak, F.
10.1101/2020.06.04.134601 — physiology — Posted on 2020-06-05
4257 T cell receptor is required for differentiation but not maintenance of intestinal intraepithelial lymphocytes
Bilate, A. M.; London, M.; Castro, T. B. R.; Mesin, L.; Kongthong, S.; Harnagel, A.; Victora, G. D.; Mucida, D.
10.1101/2020.06.04.134510 — immunology — Posted on 2020-06-05
4259 Neuropilin-1 is a host factor for SARS-CoV-2 infection
Daly, J. L.; Simonetti, B.; Anton Plagaro, C.; Kavanagh Williamson, M.; Shoemark, D. K.; Simon-Gracia, L.; Klein, K.; Bauer, M.; Hollandi, R.; Greber, U. F.; Horvath, P.; Sessions, R. B.; Helenius, A.; Hiscox, J. A.; Teesalu, T.; Matthews, D. A.; Davidson, A. D.; Cullen, P. J.; Yamauchi, Y.
10.1101/2020.06.05.134114 — cell biology — Posted on 2020-06-05
4264 JNK signalling regulates antioxidant responses in neurons
Sweeney, S. T.; Ugbode, C.; Garnham, N.; Fort-Aznar, L.; Evans, G. J. O.; Chawla, S.
10.1101/2020.06.05.136622 — neuroscience — Posted on 2020-06-05
4265 Differentiation of ciliated human midbrain-derived LUHMES neurons
Lauter, G.; Coschiera, A.; Yoshihara, M.; Sugiaman-Trapman, D.; Ezer, S.; Sethurathinam, S.; Katayama, S.; Kere, J.; Swoboda, P.
10.1101/2020.06.04.134478 — neuroscience — Posted on 2020-06-05
4267 Donor-derived mitochondrial DNA variant peptides elicit allo-specific immune response in transplant patients
Marishta, A.; Yang, Y.; Hu, X.; Jang, M. K.; Cuttin, K.; Jackson, A. M.; Luikart, H.; Deuse, T.; Khush, K. K.; Schrepfer, S.; Agbor-Enoh, S.; Valantine, H.
10.1101/2020.06.04.134965 — genomics — Posted on 2020-06-05
4269 Akt is required for artery formation during embryonic vascular development
Zhou, W.; Ristori, E.; He, L.; Ghersi, J. J.; Mehta, S.; Zhang, R.; Betsholtz, C.; Nicoli, S.; Sessa, W. C.
10.1101/2020.06.04.134718 — developmental biology — Posted on 2020-06-05
4270 Vimentin is Required for Tumor Progression and Metastasis in a Mouse Model of Non-Small Cell Lung Cancer
Berr, A. L.; Wiese, K.; dos Santos, G.; Davis, J.; Koch, C.; Anekalla, K. R.; Kidd, M.; Cheng, Y.; Hu, Y.-S.; Ridge, K.
10.1101/2020.06.04.130963 — cancer biology — Posted on 2020-06-05
4272 Long-term high-yield skeletal muscle stem cell expansion through staged perturbation of cytokine signaling in a soft hydrogel culture platform
Loiben, A. M.; Kim, K. H.; Soueid-Baumgarten, S. Y.; Aguilar, V. M.; Chin Cheong, J.; Kopyto, R. F.; Fraczek, P.; Fong, E. H. H.; Mangal, R.; Archer, L. A.; Cosgrove, B. D.
10.1101/2020.06.04.134056 — bioengineering — Posted on 2020-06-05
4274 Loss of Bone Morphogenetic Protein-binding Endothelial Regulator Causes Insulin Resistance
Mao, H.; Li, L.; Fan, Q.; Angelini, A.; Saha, P. K.; Wu, H.; Ballantyne, C. M.; Hartig, S. M.; Xie, L.; Pi, X.
10.1101/2020.06.04.134866 — pathology — Posted on 2020-06-05
4275 Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale
Driscoll, N.; Rosch, R. E.; Murphy, B. B.; Ashourvan, A.; Vishnubhotla, R.; Dickens, O. O.; Johnson, A. T. C.; Davis, K. A.; Litt, B.; Bassett, D. S.; Takano, H.; Vitale, F.
10.1101/2020.06.04.134189 — neuroscience — Posted on 2020-06-05
4277 Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntingtons Disease
Pearl, J. R.; Shetty, A. C.; Cantle, J. P.; Bergey, D. E.; Bragg, R. M.; Coffey, S. R.; Kordasiewicz, H. B.; Hood, L. E.; Price, N. D.; Ament, S. A.; Carroll, J. B.
10.1101/2020.06.04.132571 — neuroscience — Posted on 2020-06-05
4279 Structural basis of GIRK2 channel modulation by cholesterol and PIP2
Mathiharan, Y. K.; Glaaser, I. W.; Zhao, Y.; Robertson, M. J.; Skiniotis, G.; Slesinger, P. A.
10.1101/2020.06.04.134544 — neuroscience — Posted on 2020-06-05
4281 Multiple competing RNA structures dynamically control alternative splicing in human ATE1 gene
Kalinina, M.; Skvortsov, D.; Kalmykova, S.; Ivanov, T.; Dontsova, O.; Pervouchine, D.
10.1101/2020.06.04.134791 — molecular biology — Posted on 2020-06-05
4282 Several FDA-approved drugs effectively inhibit SARS-CoV-2 infection in vitro
Xiong, H.-L.; Cao, J.-L.; Shen, C.-G.; Ma, J.; Qiao, X.; Shi, T.; Yang, Y.; Ge, S.-X.; Zhang, J.; Zhang, T.-Y.; Yuan, Q.; Xia, N.-S.
10.1101/2020.06.05.135996 — microbiology — Posted on 2020-06-05
4283 Natural killer activation for bladder cancer elimination can be achieved in vitro by heat-killed BCG
Esteso, G.; Aguilo, N.; Julian, E.; Ashiru, O.; Ho, M. M.; Martin, C.; Vales-Gomez, M.
10.1101/2020.06.04.129361 — immunology — Posted on 2020-06-05
4284 Linking T cell receptor sequence to transcriptional profiles with clonotype neighbor graph analysis (CoNGA)
Schattgen, S.; Guion, K.; Crawford, J. C.; Souquette, A.; Martinez Barrio, A.; Stubbington, M. J. T.; Thomas, P. G.; Bradley, P.
10.1101/2020.06.04.134536 — immunology — Posted on 2020-06-05
4287 Molecular characterization of Fasciola gigantica in Punjab, Pakistan to infer the dispersal route among the neighbouring countries of the Indian subcontinent
Ur Rehman, Z.; Tashibu, A.; Tashiro, M.; Rashid, I.; Ali, Q.; Zahid, O.; Ashraf, K.; Shehzad, W.; Chaudhry, U.; Ichikawa-Seki, M.
10.1101/2020.06.04.134569 — genetics — Posted on 2020-06-05
4288 Metabolome shift associated with thermal stress in coral holobionts
Williams, A.; Chiles, E. N.; Conetta, D.; Pathmanathan, J. S.; Cleves, P. A.; Putnam, H. M.; Su, X.; Bhattacharya, D.
10.1101/2020.06.04.134619 — evolutionary biology — Posted on 2020-06-05
4289 Aster repulsion drives local ordering in an active system
de-Carvalho, J.; Tlili, S.; Hufnagel, L.; Saunders, T. E.; Telley, I. A.
10.1101/2020.06.04.133579 — biophysics — Posted on 2020-06-05
4292 A Tumbling Magnetic Microrobot System for Biomedical Applications
Niedert, E. E.; Bi, C.; Adam, G.; Lambert, E.; Solorio, L.; Goergen, C.; Cappelleri, D. J.
10.1101/2020.06.04.133033 — bioengineering — Posted on 2020-06-05
4293 Predicting substitutions to modulate disorder and stability in coiled-coils
Karami, Y.; Saighi, P.; Vanderhaegen, R.; Longhi, S.; Gerlier, D.; Laine, E.; Carbone, A.
10.1101/2020.06.04.131581 — bioinformatics — Posted on 2020-06-05
4295 A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
Kroll, F.; Powell, G. T.; Ghosh, M.; Antinucci, P.; Hearn, T. J.; Tunbak, H.; Lim, S.; Dennis, H. W.; Fernandez, J. M.; Hoffman, E. J.; Whitmore, D.; Dreosti, E.; Wilson, S. W.; Rihel, J.
10.1101/2020.06.04.133462 — genetics — Posted on 2020-06-05
4296 Regulation of Iron Homeostasis Through Parkin-mediated Lactoferrin Ubiquitylation
Gholkar, A. A.; Schmollinger, S.; Velasquez, E. F.; Lo, Y.-C.; Cohn, W.; Capri, J.; Dharmarajan, H.; Deardorff, W. J.; Gao, L. W.; Abdusamad, M.; Whitelegge, J. P.; Torres, J. Z.
10.1101/2020.06.04.133637 — biochemistry — Posted on 2020-06-05
4298 Distribution of droplets and immune responses after aerosol and intra-nasal delivery of influenza virus to the respiratory tract of pigs
Martini, V.; Hinchcliffe, M.; Blackshaw, E.; Joyce, M.; McNee, A.; Beverley, P.; Townsend, A.; MacLoughlin, R.; Tchilian, E.
10.1101/2020.06.04.134098 — immunology — Posted on 2020-06-05
4299 Lessons learned from bugs in models of human history
Ragsdale, A. P.; Nelson, D.; Gravel, S.; Kelleher, J.
10.1101/2020.06.04.131284 — genetics — Posted on 2020-06-05
4300 Alteration of ribosome function upon 5-fluorouracil treatment favours cancer cell drug-tolerance
Therizols, G.; Bash-Imam, Z.; Panthu, B.; Machon, C.; Vincent, A.; Nait Slimane, S.; Garcia, M.; Laforets, F.; Marcel, V.; Boubaker-Vitre, J.; Souahlia, G.; Albaret, M.-A.; Mertani, H. C.; Prudhomme, M.; Bertrand, M.; Saurin, J.-C.; Bouvet, P.; Ohlmann, T.; Guitton, J.; Dalla Venezia, N.; Pannequin, J.; Catez, F.; Diaz, J.-J.
10.1101/2020.06.04.131201 — cancer biology — Posted on 2020-06-05
4301 The Arabidopsis NRT1/PTR FAMILY Protein NPF7.3/NRT1.5 is an Indole-3-butyric Acid Transporter Involved in Root Gravitropism
Watanabe, S.; Takahashi, N.; Kanno, Y.; Suzuki, H.; Aoi, Y.; Takeda-Kamiya, N.; Toyooka, K.; Kasahara, H.; Hayashi, K.-i.; Umeda, M.; Seo, M.
10.1101/2020.06.04.131797 — plant biology — Posted on 2020-06-05
4302 A burning question: Can natural climate solutions and carbon financing save the lion from extinction?
Tear, T.; Wolff, N. H.; Lipsett-Moore, G. L.; Ritchie, M. E.; Ribeiro, N. S.; Petracca, L. S.; Lindsey, P. A.; Hunter, L.; Loveridge, A. J.; Steinbruch, F.
10.1101/2020.06.04.132084 — ecology — Posted on 2020-06-05
4303 Imaging fascicular organization of peripheral nerves with fast neural Electrical Impedance Tomography (EIT)
Ravagli, E.; Mastitkaya, S.; Thompson, N.; Iacoviello, F.; Shearing, P. R.; Perkins, J.; Gourine, A. V.; Aristovich, K.; Holder, D.
10.1101/2020.06.04.133843 — bioengineering — Posted on 2020-06-05
4304 Clathrin senses membrane curvature
Zeno, W. F.; Hochfelder, J. B.; Thatte, A. S.; Wang, L.; Gadok, A. K.; Hayden, C. C.; Lafer, E. M.; Stachowiak, J. C.
10.1101/2020.06.04.134080 — molecular biology — Posted on 2020-06-05
4306 Foot shock facilitates reward seeking in an experience-dependent manner
Strickland, J. A.; Dileo, A.; Moaddab, M.; Ray, M. H.; Walker, R.; Wright, K.; McDannald, M.
10.1101/2020.06.04.134783 — animal behavior and cognition — Posted on 2020-06-05
4312 LPHN2 controls vascular morphogenesis by inhibiting endothelial cell adhesion and YAP/TAZ signaling
Camillo, C.; Facchinello, N.; Villari, G.; Gays, D.; Gioelli, N.; Sandri, C.; Arese, M.; Tamagnone, L.; Valdembri, D.; Santoro, M. M.; Serini, G.
10.1101/2020.04.28.065979 — cell biology — Posted on 2020-06-05
4313 Single cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia
Zheng, J.; Ru, W.; Adolacion, J. R.; Spurgat, M. S.; Liu, X.; Yuan, S.; Liang, R. X.; Dong, J.; Potter, A.; Potter, S. S.; Varadarajan, N.; Tang, S.-J.
10.1101/2020.03.10.985895 — neuroscience — Posted on 2020-06-05
4316 Two novel heteropolymer-forming proteins maintain multicellular shape of the cyanobacterium Anabaena sp. PCC 7120
Springstein, B. L.; Nürnberg, D. J.; Woehle, C.; Weissenbach, J.; Theune, M. L.; Helbig, A. O.; Maldener, I.; Dagan, T.; Stucken, K.
10.1101/553073 — microbiology — Posted on 2020-06-05
4317 Quantitative Method for Assessing the Role of Lysine & Arginine Post-Translational Modifications in Nonalcoholic Steatohepatitis
Robinson, A. E.; Binek, A.; Venkatraman, V.; Searle, B. C.; Holewinski, R.; Rosenberger, G.; Parker, S. J.; Basisty, N.; Xie, X.; Lund, P. J.; Saxena, G.; Mato, J. M.; Garcia, B. A.; Schilling, B.; Lu, S. C.; Van Eyk, J. E.
10.1101/2020.01.17.910943 — systems biology — Posted on 2020-06-05
4318 The evolution of virulence in Pseudomonas aeruginosa during chronic wound infection
Vanderwoude, J.; Fleming, D.; Azimi, S.; Trivedi, U.; Rumbaugh, K. P.; Diggle, S. P.
10.1101/2020.05.29.124545 — microbiology — Posted on 2020-06-05
4319 An economic dilemma between weapon systems may explain an arachno-atypical venom in wasp spiders (Argiope bruennichi)
Lueddecke, T.; von Reumont, B. M.; Foerster, F.; Billion, A.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Lemke, S.
10.1101/2020.06.04.133660 — zoology — Posted on 2020-06-05
4323 Central processing of leg proprioception in Drosophila
Agrawal, S.; Dickinson, E. S.; Sustar, A.; Gurung, P.; Shepherd, D.; Truman, J. W.; Tuthill, J. C.
10.1101/2020.06.04.132811 — neuroscience — Posted on 2020-06-05
4324 RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site.
Haza, K. Z.; Martin, H. L.; Rao, A.; Turner, A. L.; Saunders, S. E.; Petersen, B.; Tiede, C.; Tipping, K.; Tang, A. A.; Ajayi, M.; Taylor, T.; Fishwick, K. M.; Adams, T. L.; Gaule, T. G.; Trinh, C. H.; Johnson, M.; Breeze, A. L.; Edwards, T. A.; McPherson, M. J.; Tomlinson, D. C.
10.1101/2020.06.04.133728 — molecular biology — Posted on 2020-06-05
4325 Influence of the microenvironment on the modulation of the host response by the typhoid toxin
Martin, O. C.; Butter, D.; Paparouna, E.; Theodorou, S. D.; Haykal, M. M.; Boutet-Robinet, E.; Tebaldi, T.; Bergonzini, A.; Lopez Chiloeches, M.; Wakeham, A.; Rhen, M.; Mak, T.; Gorgoulis, V.; Pateras, I. S.; Frisan, T.
10.1101/2020.06.04.133686 — immunology — Posted on 2020-06-05
4326 2D or Not 2D? An FMRI Study of How Dogs Visually Process Objects
Prichard, A.; Chhibber, R.; Athanassiades, K.; Chiu, V.; Spivak, M.; Berns, G.
10.1101/2020.06.04.134064 — animal behavior and cognition — Posted on 2020-06-05
4327 Dissection of the Spindle Assembly Checkpoint by Proximity Proteomics
Garcia, Y. A.; Velasquez, E. F.; Gao, L. A.; Cheung, K.; Clutario, K. M.; Williams-Hamilton, T.; Gholkar, A. A.; Whitelegge, J. P.; Torres, J. Z.
10.1101/2020.06.04.133710 — biochemistry — Posted on 2020-06-05
4333 Rapid characterisation of protein phase behaviour using droplet microfluidics
Arter, W. E.; Qi, R.; Krainer, G. E.; Welsh, T. J.; Xu, Y.; St George-Hyslop, P.; Alberti, S.; Knowles, T.
10.1101/2020.06.04.132308 — biophysics — Posted on 2020-06-05
4337 Sleeping While Awake: The Intrusion of Neural Activity Associated with Sleep Onset in the Awake Human Brain
Hawes, S.; Innes, C. R. H.; Parsons, N.; Drummond, S. P. A.; Caeyenberghs, K.; Jones, R. D.; Poudel, G. R.
10.1101/2020.06.04.133603 — neuroscience — Posted on 2020-06-05
4339 Evolutionary genetics of Drosophila melanogaster immunity: role of the X chromosome and sex-specific dominance
Geeta Arun, M.; Agarwala, A.; Jigisha, ; Kashyap, M.; Venkatesan, S.; Chechi, T. S.; Syed, Z. A.; Gupta, V.; Prasad, N. G.
10.1101/2020.06.03.131706 — evolutionary biology — Posted on 2020-06-05
4340 In Vitro Patients Derived Glioma Culture Model: Identification of Aggressive, Drug Resistant Phenotype Among Low-Grade Gliomas
Beevi, S. S.; Verma, V. K.; Panigrahi, M.; Bhale, A.; Madigubba, S.; Chowdary, R.; Korabathina, R.; Gopal Reddy, S.
10.1101/2020.06.04.131680 — cancer biology — Posted on 2020-06-05
4342 A monogenic and fast-responding Light-Inducible Cre recombinase as a novel optogenetic switch
Duplus-Bottin, H.; Spichty, M.; Triqueneaux, G.; Place, C.; Mangeot, P. E.; Ohlmann, T.; Vittoz, F.; Yvert, G.
10.1101/2020.06.04.132548 — synthetic biology — Posted on 2020-06-05
4345 Unveiling the inter individual variability of human fibroblasts innate immune response using robust cell-based protocols
David-Watine, B.; Chansard, A.; Poujol de Molliens, M.; Dubrulle, N.; Falanga, P. B.; Stephen, T.; Hasan, M.; van Zandbergen, G.; Aulner, N.; Shorte, S. L.; Milieu interieur Consortium,
10.1101/2020.06.04.133264 — immunology — Posted on 2020-06-05
4346 Phosphate and phosphite differentially impact the proteome and phosphoproteome of Arabidopsis suspension cell cultures
Mehta, D.; Ghahremani, M.; Perez-Fernandez, M.; Tan, M.; Schlapfer, P.; Plaxton, W. C.; Uhrig, R. G.
10.1101/2020.05.29.124040 — plant biology — Posted on 2020-06-05
4348 Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine.
Yeola, A.; Subramanian, S.; Oliver, R. A.; Lucas, C. A.; Thoms, J. A. I.; Yan, F.; Olivier, J.; Chacon, D.; Tursky, M. L.; Hung, T.; Power, C.; Hardy, P.; Ma, D. D.; McCarroll, J.; Kavallaris, M.; Hesson, L. B.; Beck, D.; Curtis, D. J.; Wong, J. W. H.; Hardeman, E. C.; Walsh, W. R.; Mobbs, R.; Chandrakanthan, V.; Pimanda, J. E.
10.1101/2020.06.04.130872 — cell biology — Posted on 2020-06-05
4349 HDAC4 controls senescence and aging by safeguarding the epigenetic identity and ensuring the genomic integrity
Di Giorgio, E.; Paluvai, H.; Dalla, E.; Ranzino, L.; Renzini, A.; Moresi, V.; Cutano, V.; Picco, R.; Brancolini, C.
10.1101/2020.06.04.132787 — cell biology — Posted on 2020-06-05
4351 Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy
Han, B.; Porta, J. C.; Hanks, J. L.; Peskova, Y.; Binshtein, E.; Dryden, K.; Claxton, D. P.; Mchaourab, H. S.; Karakas, E.; Ohi, M. D.; Kenworthy, A. K.
10.1101/2020.06.04.133678 — cell biology — Posted on 2020-06-05
4352 An ATM-MYBL2-CDC7 axis regulates replication initiation and prevents replication stress in pluripotent stem cells
Blakemore, D.; Almaghrabi, R.; Vilaplana, N.; Gonzalez, E.; Moya, M.; Murphy, G.; Stewart, G.; Gambus, A.; Petermann, E.; Garcia, P.
10.1101/2020.06.04.131276 — cell biology — Posted on 2020-06-05
4353 Fine tuning of calcium constitutive entry by optogenetically-controlled membrane polarization: impact on cell migration.
Chapotte-Baldacci, C.-A.; Lizot, G.; jajkiewicz, C.; Leveque, M.; Penna, A.; Magaud, C.; Thoreau, V.; Bois, P.; Sebille, S.; Chatelier, A.
10.1101/2020.06.04.134205 — cell biology — Posted on 2020-06-05
4355 Constitutional activation of BMP4 and WNT signalling in hESC results in impaired mesendoderm differentiation
Markouli, C.; Couvreu De Deckersberg, E.; Dziedzicka, D.; Regin, M.; Franck, S.; Keller, A.; Gheldof, A.; Geens, M.; Sermon, K.; Spits, C.
10.1101/2020.06.04.133496 — cell biology — Posted on 2020-06-05
4358 Acquisition of ionic copper by a bacterial outer membrane protein
Bhamidimarri, S.; Young, T.; Shanmugam, M.; Soderholm, S.; Basle, A.; Belzunces, B.; Skylaris, C.; Bumann, D.; Khalid, S.; van den Berg, B.
10.1101/2020.06.04.134395 — microbiology — Posted on 2020-06-05
4363 Sensitivity of radio-photoluminescence glass dosimeters to accumulated doses
Kim, D. W.; Sung, J.; Son, J.; Shin, H.-B.; Kim, M.-J.; Noh, Y.-Y.; Kim, H.; Han, M. C.; Kim, J.; Han, S. C.; Chang, K. H.; Kim, H.; Park, K.; Yoon, M.; Kim, J.; Shin, D.
10.1101/2020.06.04.133900 — cancer biology — Posted on 2020-06-05
4366 Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence
Scott, J.; Sueiro-Olivares, M.; Thornton, B. P.; Owens, R. A.; Muhamadali, H.; Fortune-Grant, R.; Thomas, R.; Hollywood, K.; Doyle, S.; Goodacre, R.; Tabernero, L.; Bignell, E.; Amich, J.
10.1101/2020.06.04.131862 — microbiology — Posted on 2020-06-05
4371 Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination
Weiss, L.; Reiner, T.; Mergner, J.; Kuster, B.; Feher, A.; Hensel, G.; Gahrtz, M.; Kumlehn, J.; Engelhardt, S.; Huckelhoven, R.
10.1101/2020.05.28.121228 — plant biology — Posted on 2020-06-05
4373 SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells
Martinat, C.; Cormier, A.; Tobaly-Tapiero, J.; Palmic, N.; Casartelli, N.; Coggins, S. A.; Buchrieser, J.; Persaud, M.; Diaz-Griffero, F.; Espert, L.; Bossis, G.; Lesage, P.; Schwartz, O.; Kim, B.; Margottin, F.; Saib, A.; Zamborlini, A.
10.1101/2020.06.04.133439 — microbiology — Posted on 2020-06-05
4374 A Parasite Coat Protein Binds Suramin to Confer Drug Resistance
Zeelen, J.; van Straaten, M.; Verdi, J.; Hempelmann, A.; Hashemi, H.; Perez, K.; Jeffrey, P. D.; Haelg, S.; Wiedemar, N.; Maeser, P.; Papavasiliou, F. N.; Stebbins, C. E.
10.1101/2020.06.04.134106 — microbiology — Posted on 2020-06-05
4375 Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Aron, Z. D.; Mehrani, A.; Hoffer, E. D.; Connolly, K. L.; Torhan, M. C.; Alumasa, J. N.; Srinivas, P.; Cabrera, M.; Hosangadi, D.; Barbor, J. S.; Cardinale, S. C.; Kwasny, S. M.; Morin, L. R.; Butler, M. M.; Opperman, T. J.; Bowlin, T. L.; Jerse, A. E.; Stagg, S. M.; Dunham, C. M.; Keiler, K. C.
10.1101/2020.06.04.132530 — microbiology — Posted on 2020-06-05
4377 Skin Lesions Classification Using Deep Learning Based on Dilated Convolution
Ratul, M. A. R.; Mozaffari, M. H.; Lee, D. W.; Parimbelli, D. E.
10.1101/860700 — cancer biology — Posted on 2020-06-05
4380 Synaptic dynamics as convolutional units
Rossbroich, J.; Trotter, D.; Toth, K.; Naud, R.
10.1101/2020.06.04.133892 — neuroscience — Posted on 2020-06-05
4381 Cardiac Microlesions Form During Severe Bacteremic Enterococcus faecalis Infection
Brown, A. O.; Singh, K. V.; Cruz, M. R.; Kaval, K. G.; Francisco, L. E.; Murray, B. E.; Garsin, D. A.
10.1101/2020.01.14.906669 — microbiology — Posted on 2020-06-05
4382 The binding mechanism of Streptococcus suis accessory virulence factor and adhesin SadP to globotetraosylceramide
Johansson, M. M.; Belurier, E.; Papageorgiou, A. C.; Sundin, A. P.; Rahkila, J.; Kallonen, T.; Nilsson, U. J.; Maatsola, S.; Nyholm, T. K. M.; Käpylä, J.; Corander, J.; Leino, R.; Finne, J.; Teneberg, S.; Haataja, S. J.
10.1101/2020.05.29.122762 — microbiology — Posted on 2020-06-05
4383 Topography and Land Use Modulate Hydrological and Nutrient Export Dynamics in two Andean Streams
Sosnovsky, A.; Lallement, M. E.; Rechencq, M.; Zattara, E. E.; Fernandez, M. V.; Leiva, S.; Suarez, M. J.; Daga, R.; Cantet, R. J.
10.1101/742411 — ecology — Posted on 2020-06-05
4384 Sorcin stimulates Activation Transcription Factor 6α (ATF6) transcriptional activity
Parks, S.; Gao, T.; Jimenez Awuapura, N.; Ayathamattam, J.; Chabosseau, P. L.; Marchetti, P.; Johnson, P.; Bosco, D.; Kalvakolanu, D. V.; Valdivia, H. H.; Rutter, G. A.; Leclerc, I.
10.1101/2020.04.23.053322 — cell biology — Posted on 2020-06-05
4385 Towards a consensus microRNA signature of primary and metastatic colorectal cancer
Fromm, B.; Hoye, E.; Bottger, P. H. M.; Domanska, D.; Kristensen, A. T.; Lund-Andersen, C.; Abrahamsen, T. W.; Fretland, A. A.; Dagenborg, V. J.; Lorenz, S.; Edwin, B.; Hovig, E.; Flatmark, K.
10.1101/2020.06.01.127647 — cancer biology — Posted on 2020-06-05
4387 Synthetic biosensor circuits generate a frequency-encoded response to phytohormones under a dynamic environment
Perez Garcia, S.; Garcia Navarrete, M.; Ruiz Sanchis, D.; Prieto Navarro, C.; Avdovic, M.; Pucciariello, O.; Wabnik, K.
10.1101/2020.05.31.125997 — synthetic biology — Posted on 2020-06-05
4389 An approach for long-term, multi-probe Neuropixels recordings in unrestrained rats
Luo, T. Z.; Bondy, A. G.; Gupta, D.; Elliott, V. A.; Kopec, C. D.; Brody, C. D.
10.1101/2020.04.13.039305 — neuroscience — Posted on 2020-06-04
4391 Mercury methylation by metabolically versatile and cosmopolitan marine bacteria
Lin, H.; Ascher, D. B.; Myung, Y.; Lamborg, C. H.; Hallam, S. J.; Gionfriddo, C. M.; Holt, K. E.; Moreau, J. W.
10.1101/2020.06.03.132969 — microbiology — Posted on 2020-06-04
4395 Identification of rare transient somatic cell states induced by injury and required for whole-body regeneration
Benham-Pyle, B. W.; Brewster, C. E.; Kent, A. M.; Mann, F. G.; Chen, S.; Scott, A. R.; Box, A. C.; Sanchez Alvarado, A.
10.1101/2020.06.04.132753 — developmental biology — Posted on 2020-06-05
4398 Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles
Yabukarski, F.; Biel, J. T.; Pinney, M. M.; Doukov, T.; Powers, A. S.; Fraser, J. S.; Herschlag, D.
10.1101/786327 — biophysics — Posted on 2020-06-04
4402 Intravital multi-modal flux analysis reveals the transport mechanism of bile acids through hepatic microconduits
Vartak, N.; Guenther, G.; Joly, F.; Damle-Vartak, A.; Wibbelt, G.; Fickel, J.; Jörs, S.; Begher-Tibbe, B.; Friebel, A.; Wansing, K.; Ghallab, A.; Rosselin, M.; Boissier, N.; Vignon-Clementel, I.; Hedberg, C.; Geisler, F.; Hofer, H.; Jansen, P.; Hoehme, S.; Drasdo, D.; Hengstler, J. G.
10.1101/778803 — physiology — Posted on 2020-06-04
4406 An emerging role of Prevotella histicola on estrogen-deficiency induced bone loss through the gut microbiota-bone axis
Wang, Z.; Chen, K.; Wu, C.; Chen, J.; Pan, H.; Liu, Y.; Wu, P.; Yuan, J.; Lang, J.; Du, J.; Xu, J.; Jin, K.; Chen, L.
10.1101/2020.06.03.133082 — microbiology — Posted on 2020-06-04
4407 Integrated genomic view of SARS-CoV-2 in India
Kumar, P.; Pandey, R.; Sharma, P.; Dhar, M.; Vivekanand, A.; Bharathram, U.; Vashistha, H.; Wadhwa, S.; Tyagi, N.; Fatihi, S.; Sharma, U.; Singh, P.; Lall, H.; Datta, M.; Gupta, P.; Saini, N.; Tiwari, A.; Nandi, B.; Kumar, D.; Bag, S.; Deepanshi, D.; Rathore, S.; Jatana, N.; Jaiswal, V.; Gogia, H.; Madan, P.; Singh, S.; Singh, P.; Dash, D.; Bala, M.; Kabra, S.; Singh, S. K.; Mukerji, M.; Thukral, L.; Faruq, M.; Agarwal, A.; Rakshit, P.
10.1101/2020.06.04.128751 — microbiology — Posted on 2020-06-04
4408 Pharmacogenetics at scale: An analysis of the UK Biobank
McInnes, G. M.; Lavertu, A.; Sangkuhl, K.; Klein, T. E.; Whirl-Carrillo, M.; Altman, R. B.
10.1101/2020.05.30.125583 — genomics — Posted on 2020-06-04
4410 SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways
Eenjes, E.; Buscop-van Kempen, M.; Boerema-de Munck, A.; de Kreij-de Bruin, L.; Schnater, M.; Tibboel, D.; Collins, J.; Rottier, R.
10.1101/2020.06.04.134338 — cell biology — Posted on 2020-06-04
4411 Comparative proximity biotinylation implicates RAB18 in cholesterol mobilization and biosynthesis
Kiss, R. S.; Chicoine, J.; Khalil, Y.; Sladek, R.; Chen, H.; Pisaturo, A.; Martin, C.; Dale, J. D.; Brudenell, T. A.; Kamath, A.; Paci, E.; Clayton, P.; Wills, J. C.; von Kriegsheim, A.; Nilsson, T.; Sheridan, E.; Handley, M. T.
10.1101/871517 — cell biology — Posted on 2020-06-04
4412 Patient Similarity Network of Multiple Myeloma Identifies Patient Sub-groups with Distinct Genetic and Clinical Features
Bhalla, S.; Melnekoff, D. T.; Keats, J.; Onel, K.; Madduri, D.; Richter, J.; Richard, S.; Chari, A.; Cho, H. J.; Dudley, J. T.; Jagannath, S.; Lagana, A.; Parekh, S.
10.1101/2020.06.02.129767 — cancer biology — Posted on 2020-06-04
4415 Dynamic Loading of Human Engineered Heart Tissue Enhances Contractile Function and Drives Desmosome-linked Disease Phenotype
Bliley, J. M.; Vermeer, M.; Duffy, R. M.; Batalov, I.; Kramer, D.; Tashman, J. W.; Shiwarski, D. J.; Lee, A.; Teplenin, A. S.; Volkers, L.; Coffin, B.; Hoes, M. F.; Kalmykov, A.; Palchesko, R. N.; Sun, Y.; Jongbloed, J. D. H.; Bomer, N.; de Boer, R. A.; Suurmeijer, A. J. H.; Pijnappels, D. A.; Bolling, M. C.; Meer, P. v. d.; Feinberg, A. W.
10.1101/2020.05.25.111690 — bioengineering — Posted on 2020-06-04
4422 Further biochemical profiling of Hypholoma fasciculare metabolome reveals its chemo-genetic diversity
Al-Salihi, S.; Bull, I.; Al-Salhi, R. A.; Gates, P. J.; Salih, K.; Bailey, A. M.; Foster, G. D.
10.1101/2020.05.28.122176 — molecular biology — Posted on 2020-06-04
4423 Grazing pressure-induced shift in planktonic bacterial communities with the dominance of acIII-A1 actinobacterial lineage in soda pans
Szabo, A.; Korponai, K.; Somogyi, B.; Vajna, B.; Voros, L.; Horvath, Z.; Boros, E.; Szabo-Tugyi, N.; Marialigeti, K.; Felfoldi, T.
10.1101/2020.06.04.133827 — microbiology — Posted on 2020-06-04
4425 Hypothetical Human Immune Genome Complex Gradient May Help To Explain The Congenital Zika Symdrome Catastrophe In Brazil: A New Theory
Oliveira, F.; Bresani-Salvi, C.; Morais, C.; Bigham, A.; Braga-Neto, U.; Maestre, G.; Vandebergh, J. L.; Marques, E.; Acioli-Santos, B.
10.1101/2020.06.03.132878 — genetics — Posted on 2020-06-04
4429 The evolution of Sox gene repertoires and regulation of segmentation in arachnids
Baudouin-Gonzalez, L.; Schoenauer, A.; Harper, A.; Blakeley, G.; Seiter, M.; Arif, S.; Sumner-Rooney, L.; Russell, S.; Sharma, P. P.; McGregor, A. P.
10.1101/2020.06.04.133389 — developmental biology — Posted on 2020-06-04
4431 Mutational processes impact the evolution of anti-EGFR antibody resistance in colorectal cancer
Woolston, A.; Barber, L. J.; Griffiths, B.; Matthews, N.; Rao, S.; Watkins, D.; Chau, I.; Starling, N.; Cunningham, D.; Gerlinger, M.
10.1101/2020.05.07.082339 — cancer biology — Posted on 2020-06-04
4434 Abuse liability, antinociceptive, and discriminative stimulus properties of IBNtxA
Islam, A.; Rahman, M. A.; Brenner, M. B.; Moore, A.; Kellmyer, A.; Buechler, H.; DiGiorgio, F.; Verchio, V.; McCracken, L.; Sumi, M.; Hartley, R.; Lizza, J. R.; Moura-Letts, G.; Ficher, B. D.; Keck, T. M.
10.1101/2020.05.30.125450 — pharmacology and toxicology — Posted on 2020-06-04
4436 Reduced intra- and inter-individual diversity of semantic representations in the brains of schizophrenia patients
Nishida, S.; Matsumoto, Y.; Yoshikawa, N.; Son, S.; Murakami, A.; Hayashi, R.; Nishimoto, S.; Takahashi, H.
10.1101/2020.06.03.132928 — neuroscience — Posted on 2020-06-04
4437 Optical TrkB activation in Parvalbumin interneurons regulates intrinsic states to orchestrate cortical plasticity
Winkel, F.; Voigt, M. B.; Didio, G.; Mateo, S.; Jetsonen, E.; Llach Pou, M.; Steinzeig, A.; Ryazantseva, M.; Harkki, J.; Englund, J.; Khirug, S.; Rivera, C.; Palva, S.; Taira, T.; Lauri, S.; Umemori, J.; Castren, E.
10.1101/2020.04.27.063503 — neuroscience — Posted on 2020-06-04
4439 Seasonal variation in brain mu-opioid receptor availability
Sun, L.; Tang, J.; Liljenback, H.; Honkaniemi, A.; Virta, J.; Isojarvi, J.; Karjalainen, T.; Kantonen, T.; Nuutila, P.; Hietala, J.; Kaasinen, V.; Kalliokoski, K.; Hirvonen, J.; Scheinin, H.; Helin, S.; Eerola, K.; Savontaus, E.; Yatkin, E.; Rinne, J. O.; Roivainen, A.; Nummenmaa, L.
10.1101/2020.05.20.104349 — neuroscience — Posted on 2020-06-04
4442 Dynamic dopaminergic activity controls the timing of self-timed movement
Hamilos, A. E.; Spedicato, G.; Hong, Y.; Sun, F.; Li, Y.; Assad, J. A.
10.1101/2020.05.13.094904 — neuroscience — Posted on 2020-06-04
4446 Dual thermal ecotypes detected within a nearly genetically-identical population of the unicellular marine cyanobacterium Synechococcus
Kling, J.; Lee, M. D.; Webb, E. A.; Coelho, J. T.; Wilburn, P.; Anderson, S. I.; Zhou, Q.; Wang, C.; Phan, M. D.; Kremer, C. T.; Litchman, E.; Rynearson, T. A.; Hutchins, D. A.
10.1101/2020.05.27.119842 — microbiology — Posted on 2020-06-04
4448 Systematic analysis of mutational spectra associated with DNA repair deficiency in C. elegans
Meier, B.; Volkova, N. N.; Hong, Y.; Bertolini, S.; Gonzalez-Huici, V.; Petrova, T.; Boulton, S.; Campbell, P. J.; Gerstung, M.; Gartner, A.
10.1101/2020.06.04.133306 — genomics — Posted on 2020-06-04
4450 Combination of favorable gene haplotypes plays an important role in rice hybrid grain quality traits based on genome-wide association analysis
Li, L.; Zheng, X.; Zhang, X.; Xu, K.; Song, S.; Su, J.; Wu, C.; Li, Z.; Tang, W.; Diao, Y.; Tang, Z.; Yuan, Z.; Hu, Z.
10.1101/2020.06.04.134023 — genetics — Posted on 2020-06-04
4452 Population-level sensitivity to landscape variables reflects individual-based habitat selection in a woodland bat species
Jan, P.-L.; Zarzoso-Lacoste, D.; Fourcy, D.; Baudouin, A.; Farcy, O.; Boireau, J.; Le Gouar, P.; Puechmaille, S. J.; Petit, E. J.
10.1101/752733 — ecology — Posted on 2020-06-04
4455 Single cell resolution regulatory landscape of the mouse kidney highlights cellular differentiation programs and renal disease targets
Miao, Z.; Balzer, M. S.; Ma, Z.; Liu, H.; Wu, J.; Shrestha, R.; Aranyi, T.; Kwan, A.; Kondo, A.; Pontoglio, M.; Kim, J.; Li, M.; Kaestner, K. H.; Susztak, K.
10.1101/2020.05.24.113910 — developmental biology — Posted on 2020-06-04
4456 Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs
Lorzadeh, A.; Hammond, C.; Knapp, D.; Cao, Q.; Wang, F.; Heravi-Moussavi, A.; Wong, M.; Bilenky, M.; Moksa, M.; Sharafianardakani, Z.; Lavoie, P.; Eaves, C.; Hirst, M.
10.1101/647438 — cell biology — Posted on 2020-06-04
4457 Kinobead Profiling Reveals Reprogramming of B-cell Receptor Signaling in Response to Therapy Within Primary Chronic Lymphocytic Leukemia Cells.
Linley, A. J.; Karydis, L.; Mondru, A.; D'Avola, A.; Cicconi, S.; Griffin, R.; Forconi, F.; Pettitt, A. R.; Kalakonda, N.; Rawstron, A.; Hillmen, P.; Steele, A. J.; MacEwan, D. J.; Packham, G.; Prior, I.; Slupsky, J.
10.1101/841312 — cancer biology — Posted on 2020-06-04
4459 The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals
Bastian, F. B.; Roux, J.; Niknejad, A.; Comte, A.; Fonseca Costa, S. S.; Mendes de Farias, T.; Moretti, S.; Parmentier, G.; Rech de Laval, V.; Rosikiewicz, M.; Wollbrett, J.; Echchiki, A.; Gharib, W. H.; Gonzales-Porta, M.; Jarosz, Y.; Laurenczy, B.; Moret, P.; Person, E.; Roelli, P.; Sanjeev, K.; Seppey, M.; Robinson-Rechavi, M.
10.1101/2020.05.28.119560 — bioinformatics — Posted on 2020-06-04
4461 Evaluation of Mosaicism and Off Target Mutations in CRISPR-Mediated Genome Edited Bovine Embryos
Henning, S. L.; Owen, J. R.; Lin, J. C.; Young, A. E.; ROSS, P. J.; Van Eenennaam, A. L.; Murray, J. D.
10.1101/2020.06.04.134759 — bioengineering — Posted on 2020-06-04
4465 Single-dimensional human brain signals for two-dimensional economic choice options
Chi U Seak, L.; Volkmann, K.; Pastor-Bernier, A.; Grabenhorst, F.; Schultz, W.
10.1101/2020.04.06.028001 — neuroscience — Posted on 2020-06-04
4466 An Autonomous Molecular Bioluminescent Reporter (AMBER) for voltage imaging in freely moving animals
Srinivasan, P.; Griffin, N. M.; Joshi, P.; Thakur, D. P.; Nguyen-Le, A.; McCotter, S.; Jain, A.; Saeidi, M.; Kulkarni, P.; Eisdorfer, J.; Rothman, J.; Montell, C.; Theogarajan, L. S.
10.1101/845198 — neuroscience — Posted on 2020-06-04
4467 Olfactory transmucosal SARS-CoV-2 invasion as port of Central Nervous System entry in COVID-19 patients
Meinhardt, J.; Radke, J.; Dittmayer, C.; Mothes, R.; Franz, J.; Laue, M.; Schneider, J.; Bruenink, S.; Hassan, O.; Stenzel, W.; Windgassen,, M.; Roessler, L.; Goebel, H.-H.; Martin, H.; Nitsche, A.; Schulz-Schaeffer, W.; Hakroush, S.; Winkler, M. S.; Tampe, B.; Elezkurtaj, S.; Horst, D.; Oesterhelweg, L.; Tsokos, M.; Ingold Heppner, B.; Stadelmann, C.; Drosten, C.; Corman, V. M.; Radbruch, H.; Heppner, F. L.
10.1101/2020.06.04.135012 — neuroscience — Posted on 2020-06-04
4469 Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors
Abo, K. M.; Ma, L.; Matte, T.; Huang, J.; Alysandratos, K. D.; Werder, R. B.; Mithal, A.; Beermann, M. L.; Lindstrom-Vautrin, J.; Mostoslavsky, G.; Ikonomou, L.; Kotton, D. N.; Hawkins, F.; Wilson, A.; Villacorta-Martin, C.
10.1101/2020.06.03.132639 — molecular biology — Posted on 2020-06-04
4470 The Zinc Finger Antiviral Protein restricts SARS-CoV-2
Nchioua, R.; Kmiec, D.; Mueller, J.; Conzelmann, C.; Gross, R.; Swanson, C. M.; Neil, S.; Stenger, S.; Sauter, D.; Muench, J.; Sparrer, K. M.; Kirchhoff, F.
10.1101/2020.06.04.134379 — microbiology — Posted on 2020-06-04
4471 SARS-CoV2 Testing: The Limit of Detection Matters
Arnaout, R.; Lee, R.; Lee, G. R.; Callahan, C.; Yen, C. F.; Smith, K. P.; Arora, R.; Kirby, J. E.
10.1101/2020.06.02.131144 — microbiology — Posted on 2020-06-04
4472 Examination of a first-in-class bis-dialkylnorspermidine-terphenyl antibiotic in topical formulation against mono and polymicrobial biofilms
Williams, D.; Miller, M.; Rogers, J.; Badham, M.; Cadenas, L.; Brightwell, E.; Adams, J.; Tyler, C.; Sebahar, P.; Haussener, T.; Reddy, H.; Looper, R.
10.1101/2020.06.04.133934 — microbiology — Posted on 2020-06-04
4474 Reduced antibacterial drug resistance and blaCTX-M β-lactamase gene carriage in cattle-associated Escherichia coli at low temperatures, at sites dominated by older animals and on pastureland: implications for surveillance.
Schubert, H.; Morley, K.; Puddy, E. F.; Arbon, R.; Findlay, J.; Mounsey, O.; Gould, V. C.; Vass, L.; Evans, M.; Rees, G. M.; Barrett, D. C.; Turner, K. M.; Cogan, T. A.; Avison, M. B.; Reyher, K. K.
10.1101/778407 — microbiology — Posted on 2020-06-04
4475 DYNAMIC CLONAL HEMATOPOIESIS AND FUNCTIONAL T-CELL IMMUNITY IN A SUPER-CENTENARIAN
van den Akker, E. B.; Makrodimitris, S.; Hulsman, M.; Brugman, M. H.; Nikolic, T.; Bradley, T.; Waisfisz, Q.; Baas, F.; Jakobs, M. E.; de Jong, D.; Slagboom, P. E.; Staal, F. J.; Reinders, M. J.; Holstege, H.
10.1101/788752 — immunology — Posted on 2020-06-04
4476 The role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization
Chen, J.; Xiong, Z.; Miller, D.; Yu, Z.; McCroskey, S.; Bradford, W.; Cavanaugh, A.; Jaspersen, S. L.
10.1101/2020.06.04.133975 — genetics — Posted on 2020-06-04
4477 Controlling the speed and trajectory of evolution with counterdiabatic driving
Iram, S.; Dolson, E.; Chiel, J.; Pelesko, J.; Krishnan, N.; Güngör, O.; Kuznets-Speck, B.; Deffner, S.; Ilker, E.; Scott, J. G.; Hinczewski, M.
10.1101/867143 — evolutionary biology — Posted on 2020-06-04
4483 Landscape and Selection of Vaccine Epitopes in SARS-CoV-2
Smith, C. C.; Entwistle, S.; Willis, C.; Vensko, S.; Beck, W.; Garness, J.; Sambade, M.; Routh, E.; Olsen, K.; Kodysh, J.; O'Donnell, T.; Haber, C.; Heiss, K.; Stadler, V.; Garrison, E.; Grant, O. C.; Woods, R.; Heise, M.; Vincent, B. G.; Rubinsteyn, A.
10.1101/2020.06.04.135004 — immunology — Posted on 2020-06-04
4485 Factors Influencing Precision Medicine Knowledge and Attitudes
Chakravarthy, R.; Stallings, S. C.; Williams, M.; Hollister, M.; Davidson, M.; Canedo, J.; Wilkins, C.
10.1101/2020.06.04.133942 — genetics — Posted on 2020-06-04
4486 Common breast cancer risk loci predispose to distinct tumor subtypes
Ahearn, T. U.; Zhang, H.; Michailidou, K.; Milne, R. L.; Bolla, M. K.; Dennis, J.; Dunning, A. M.; Lush, M.; Wang, Q.; Andrulis, I. L.; Anton-Culver, H.; Arndt, V.; Aronson, K. J.; Auer, P. L.; Augustinsson, A.; Baten, A.; Becher, H.; Behrens, S.; Benitez, J.; Bermisheva, M.; Blomqvist, C.; Bojesen, S. E.; Bonanni, B.; Borresen-Dale, A.-L.; Brauch, H.; Brenner, H.; Brooks-Wilson, A.; Bruning, T.; Burwinkel, B.; Canzian, F.; Castelao, J. E.; Chang-Claude, J.; Chanock, S.; Chenevix-Trench, G.; Clarke, C. L.; NBCS Collaborators, ; Collee, J. M.; Cox, A.; Cross, S. S.; Czene, K.; Daly, M. B.; Dev
10.1101/733402 — genetics — Posted on 2020-06-04
4492 Allosteric communications between domains modulate activity of matrix metalloprotease-1
Kumar, L.; Nash, A.; Harms, C.; Planas, J.; Wright, D.; Klein-Seetharaman, J.; Sarkar, S. K.
10.1101/804559 — biophysics — Posted on 2020-06-04
4493 Protein structure-based gene expression signatures
Rahman, R.; Xiong, Y.; van Hasselt, J. G. C.; Hansen, J.; Sobie, E.; Birtwistle, M. R.; Azeloglu, E. U.; Iyengar, R.; Schlessinger, A.
10.1101/2020.06.03.133066 — bioinformatics — Posted on 2020-06-04
4495 Transcriptome analysis of three Agave fiber-producing cultivars suitable for biochemicals and biofuels production in semiarid regions
Raya, F. T.; Marone, M. P.; Carvalho, L. M.; Rabelo, S. C.; Paula, M. S.; Campanari, M. F. Z.; Freschi, L.; Mayer, J. L. S.; Silva, O. R. R. F.; Mieczkowski, P.; Carazzolle, M. F.; Pereira, G. A. G.
10.1101/2020.06.03.132837 — plant biology — Posted on 2020-06-04
4496 Direct colorimetric LAMP assay for in-field detection of African swine fever virus: a validation study during an outbreak in Vietnam
Tran, D. H.; Tran, H. T.; Le, U. P.; Vu, X. D.; Trinh, T. B. N.; Do, H. D. K.; Than, V. T.; Bui, L. M.; Vu, V. V.; Nguyen, T. L.; Phung, H. T. T.; Le, V. P.
10.1101/2020.06.03.132944 — molecular biology — Posted on 2020-06-04
4497 Pitfalls in SARS-CoV-2 PCR diagnostics
Wernike, K.; Keller, M.; Conraths, F. J.; Mettenleiter, T. C.; Groschup, M. H.; Beer, M.
10.1101/2020.06.03.132357 — microbiology — Posted on 2020-06-04
4499 In silico saturation mutagenesis of cancer genes
Muinos, F.; Martinez-Jimenez, F.; Pich, O.; Gonzalez-Perez, A.; Lopez-Bigas, N.
10.1101/2020.06.03.130211 — cancer biology — Posted on 2020-06-04
4501 Massively parallel functional testing of MSH2 missense variants conferring Lynch Syndrome risk
Jia, X.; Burugula, B. B.; Chen, V.; Lemons, R. M.; Jayakody, S.; Maksutova, M.; Kitzman, J. O.
10.1101/2020.06.03.133017 — genetics — Posted on 2020-06-04
4502 Precision genetic cellular models identify therapies protective against endoplasmic reticulum stress
Lebedeva, I. V.; Wagner, M. V.; Sahdeo, S.; Lu, Y.-F.; Anyanwu-Ofili, A.; Harms, M. B.; Wadia, J. S.; Rajagopal, G.; Boland, M. J.; Goldstein, D. B.
10.1101/2020.06.03.132886 — neuroscience — Posted on 2020-06-04
4503 Precision combination therapies from recurrent oncogenic co-alterations
Li, X.; Dowling, E.; Yan, G.; Bozorgui, B.; Imanirad, P.; Elnaggar, J. H.; Luna, A.; Sander, C.; Korkut, A.
10.1101/2020.06.03.132514 — cancer biology — Posted on 2020-06-04
4504 SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals
Lam, S. D.; Bordin, N.; Waman, V. P.; Scholes, H. M.; Ashford, P.; Sen, N.; van Dorp, L.; Rauer, C.; Dawson, N. L.; Pang, C. S.; Abbasian, M.; Sillitoe, I.; Edwards, S. J.; Fraternali, F.; Lees, J. G.; Santini, J. M.; Orengo, C. A.
10.1101/2020.05.01.072371 — bioinformatics — Posted on 2020-06-04
4505 Tomato fruit susceptibility to fungal disease can be uncoupled from ripening by suppressing susceptibility factors
Silva, C. J.; van den Abeele, C.; Ortega Salazar, I.; Papin, V.; Adaskaveg, J. A.; Wang, D.; Casteel, C. L.; Seymour, G. B.; Blanco-Ulate, B.
10.1101/2020.06.03.132829 — plant biology — Posted on 2020-06-04
4506 Improved Monoisotopic Mass Estimation for Deeper Proteome Coverage
Rad, R.; Li, J.; Mintseris, J.; O'Connell, J.; Gygi, S. P.; Schweppe, D. K.
10.1101/2020.06.03.131003 — bioinformatics — Posted on 2020-06-04
4507 Sustained attention and vigilance deficits associated with HIV and a history of methamphetamine dependence
Pocuca, N.; Young, J. W.; MacQueen, D. A.; Letendre, S.; Heaton, R. K.; Geyer, M. A.; Perry, W.; Grant, I.; Minassian, A.; Translational Methamphetamine AIDS Research Center (TMARC),
10.1101/2020.06.03.132522 — neuroscience — Posted on 2020-06-04
4509 Instantaneous amplitude and shape of postrhinal theta oscillations differentially encode running speed
Ghosh, M.; Shanahan, B. E.; Furtak, S. C.; Mashour, G. A.; Burwell, R. D.; Ahmed, O. J.
10.1101/2020.06.03.130609 — neuroscience — Posted on 2020-06-04
4512 Insights into the salivary N-glycome of Lutzomyia longipalpis, vector of visceral leishmaniasis
Mondragon-Shem, K.; Wongtrakul-Kish, K.; Kozak, R. P.; Yan, S.; Wilson, I.; Paschinger, K.; Rogers, M. E.; Spencer, D. I. R.; Acosta-Serrano, A.
10.1101/2020.06.03.132746 — biochemistry — Posted on 2020-06-04
4513 A Genomics Resource for Genetics, Physiology, and Breeding of West African Sorghum
Faye, J. M.; Maina, F.; Akata, E. A.; Sine, B.; Diatta, C.; Mamadou, A.; Marla, S. R.; Bouchet, S.; Teme, N.; Rami, J.-F.; Fonceka, D.; Cisse, N.; Morris, G. P.
10.1101/2020.06.03.132217 — genomics — Posted on 2020-06-04
4515 Ultrasensitive single-cell proteomics workflow identifies >1000 protein groups per mammalian cell
Cong, Y.; Motamedchaboki, K.; Misal, S.; Liang, Y.; Guise, A.; Truong, T.; Huguet, R.; Plowey, E. D.; Zhu, Y.; Lopez-Ferrer, D.; Kelly, R. T.
10.1101/2020.06.03.132449 — systems biology — Posted on 2020-06-04
4520 Selective Vulnerability of Senescent Glioblastoma Cells to Bcl-XL Inhibition
Rahman, M.; Olson, I. E.; Mansour, M.; Carlstrom, L. P.; Sutiwisesak, R.; Saber, R.; Rajani, K.; Warrington, A. E.; Howard, A.; Schroeder, M.; Chen, S.; Decker, P. A.; Zhu, Y.; Parney, I. F.; Burma, S.; Brown, D.; Rodriguez, M.; Sarkaria, J. N.; Kirkland, J.; Burns, T.
10.1101/2020.06.03.132712 — cancer biology — Posted on 2020-06-04
4522 Multi-Omic Analysis Reveals Cannabidiol Disruption of Cholesterol Homeostasis in Human Cell Lines
Guard, S. E.; Chapnick, D. A.; Ebmeier, C. C.; Poss, Z. C.; Jacobsen, J.; Nemkov, T.; Ball, K. A.; Webb, K. J.; Simpson, H. L.; Coleman, S.; Bunker, E.; Ramirez, A.; Reisz, J. A.; Sievers, R.; Stowell, M. H.; D'Alessandro, A.; Liu, X.; Old, W. M.
10.1101/2020.06.03.130864 — systems biology — Posted on 2020-06-04
4523 Spatio-temporal surveys of the brown meagre Sciaena umbra using passive acoustics for management and conservation
Di Iorio, L.; Bonhomme, P.; Michez, N.; Ferrari, B.; Gigou, A.; Panzalis, P.; Desidera, E.; Navone, A.; Boissery, P.; Lossent, J.; Cadville, B.; Bravo-Monin, M.; Charbonnel, E.; Gervaise, C.
10.1101/2020.06.03.131326 — ecology — Posted on 2020-06-04
4526 Understanding the Role of Macrophages in Lung Inflammation Through Mathematical Modeling
Minucci, S. B.; Valentine, M. S.; Kamga Gninzeko, F. J.; Heise, R. L.; Reynolds, A. M.
10.1101/2020.06.03.132258 — systems biology — Posted on 2020-06-04
4532 Codon arrangement modulates MHC-I peptides presentation
Daouda, T.; Dumont-Lagacé, M.; Feghaly, A.; Benslimane, Y.; Panes, R.; Courcelles, M.; Benhammadi, M.; Harrington, L.; Thibault, P.; Major, F.; Bengio, Y.; Gagnon, E.; Lemieux, S.; Perreault, C.
10.1101/2020.06.03.078824 — bioinformatics — Posted on 2020-06-04
4536 Impact of the radiated brain microenvironment on a panel of human patient-derived xenografts.
Zhang, J.; Olson, I. E.; Carlstrom, L. P.; Rahman, M.; Rajani, K.; Gupta, K.; Liu, L.; Tang, Z.; Sananikone, E. F.; Dong, A.; Warrington, A. E.; Rodriguez, M.; Chen, J.; Schroeder, M. A.; Ikram, S.; Sarkaria, J. N.; Burma, S.; Burns, T. C.
10.1101/2020.06.03.132365 — cancer biology — Posted on 2020-06-04
4537 pH dependent inhibition from ammonium ions in the Pseudomonas mevalonii HMG-CoA Reductase crystallization environment
Purohit, V.; Steussy, C. N.; Rosales, A. R.; Critchelow, C. D.; Schmidt, T.; Helquist, P.; Wiest, O.; Mesecar, A. D.; Stauffacher, C. V.
10.1101/2020.06.03.132290 — biochemistry — Posted on 2020-06-04
4538 20 years of African Neuroscience: Waking a sleeping giant
Maina, M. B.; Ahmad, U.; Harun, I. A.; Kwairanga, H. S.; Nasr, F. E.; Salihu, A. T.; Abushouk, A. I.; Muhammad, A.; Awadelkareem, M. A.; Amin, A.; Imam, A.; Akinrinade, I. D.; Yakubu, A. H.; Azeez, I. A.; Mohammed, Y. G.; Adamu, A. A.; Ibrahim, B. H.; Bukar, A. M.; Yaro, A. U.; Prieto-Godino, L. L.; Baden, T.
10.1101/2020.06.03.131391 — scientific communication and education — Posted on 2020-06-04
4539 The impact of transposable elements on tomato diversity
Dominguez, M.; Dugas, E.; Benchouaia, M.; Leduque, B.; Jimenez-Gomez, J.; Colot, V.; Quadrana, L.
10.1101/2020.06.04.133835 — plant biology — Posted on 2020-06-04
4543 VipariNama: RNA vectors to rapidly reprogram plant morphology and metabolism
Khakhar, A.; Wang, C.; Swanson, R.; Stokke, S.; Rizvi, F.; Sarup, S.; Hobbs, J.; Voytas, D. F.
10.1101/2020.06.03.130179 — plant biology — Posted on 2020-06-04
4546 The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation
Li, F.; Lo, T. Y.; Miles, L.; Wang, Q.; Li, D.; Niu, J.; Goldshteyn, J. I.; Wang, C.; Wang, S.; Qiu, J.; Trombley, S.; Pogoda, K.; Brewster, M.; Rompolas, P.; He, Y.; Janmey, P. A.; Thomas, G. M.; Song, Y.
10.1101/2020.06.03.132126 — neuroscience — Posted on 2020-06-04
4547 Impact of Comorbidities on SARS-CoV-2 Viral Entry-Related Genes
Breidenbach, J. D.; Dube, P.; Ghosh, S.; Modyanov, N. N.; Malhotra, D.; Dworkin, L. D.; Haller, S. T.; Kennedy, D. J.
10.1101/2020.05.26.117440 — microbiology — Posted on 2020-06-04
4548 Potential antiviral options against SARS-CoV-2 infection
Ianevski, A.; Yao, R.; Fenstad, M. H.; Biza, S.; Zusinaite, E.; Lysvand, H.; Loeseth, K.; Lamndsem, V. M.; Malmring, J. F.; Oksenych, V.; Erlandsen, S. E.; Aas, P. A.; Hagen, L.; Pettersen, C. H.; Afset, J. E.; Nordbo, S. A.; Bjoras, M.; Kainov, D. E.
10.1101/2020.05.12.091165 — microbiology — Posted on 2020-06-04
4550 Glutamatergic adaptation to stress in medial prefrontal cortex underlies risk and resilience for pessimistic beliefs
Cooper, J. A.; Nuutinen, M. R.; Lawlor, V. M.; DeVries, B. A. M.; Barrick, E. M.; Hossein, S.; Cole, D. C.; Leonard, C. V.; Teer, A. P.; Shields, G. S.; Slavich, G. M.; Öngür, D.; Jensen, J. E.; Du, F.; Pizzagalli, D. A.; Treadway, M.
10.1101/2020.06.03.131946 — neuroscience — Posted on 2020-06-04
4551 A protocol for adding knowledge to Wikidata, a case report
Waagmeester, A.; Willighagen, E. L.; Su, A. I.; Kutmon, M.; Gayo, J. E. L.; Fernandez-Alvarez, D.; Groom, Q.; Schaap, P. J.; Verhagen, L. M.; Koehorst, J. J.
10.1101/2020.04.05.026336 — bioinformatics — Posted on 2020-06-04
4552 Direct visualization and characterization of the human zona incerta and surrounding structures
Lau, J. C.; Xiao, Y.; Haast, R. A.; Gilmore, G.; Uludag, K.; MacDougall, K. W.; Menon, R. R.; Parrent, A. G.; Peters, T. M.; Khan, A. R.
10.1101/2020.03.25.008318 — neuroscience — Posted on 2020-06-04
4555 Typical lipreading and audiovisual speech perception without motor simulation
vannuscorps, g.; Andres, M.; Carneiro Pereira, S.; Rombaux, E.; Caramazza, A.
10.1101/2020.06.03.131813 — neuroscience — Posted on 2020-06-04
4556 Whi5 is diluted and protein synthesis does not dramatically increase in pre-Start G1
Schmoller, K. M.; Lanz, M. C.; Kim, J.; Koivomagi, M.; Qu, Y.; Tang, C.; Kukhtevich, I. V.; Schneider, R.; Rudolf, F.; Moreno, D. F.; Aldea, M.; Lucena, R.; Kellogg, D.; Skotheim, J. M.
10.1101/2020.06.01.126599 — molecular biology — Posted on 2020-06-04
4557 Polygenic Scores for Cognitive Abilities and their Association with Different Aspects of General Intelligence - a Deep Phenotyping Approach
Genc, E.; Schlüter, C.; Fraenz, C.; Arning, L.; Nguyen, H. P.; Voelkle, M. C.; Streit, F.; Güntürkün, O.; Kumsta, R.; Ocklenburg, S.
10.1101/2020.06.03.131318 — genetics — Posted on 2020-06-04
4559 Frequent assembly of chimeric complexes in the protein interaction network of an interspecies hybrid
Dandage, R.; Berger, C. M.; Gagnon-Arsenault, I.; Moon, K.-M.; Stacey, R. G.; Foster, L. J.; Landry, C. R.
10.1101/2020.06.02.130567 — evolutionary biology — Posted on 2020-06-04
4560 The Sequenced Genomes of Non-Seed Land Plants Reveal the (R)Evolutionary History of Peptide Signaling
Furumizu, C.; Krabberod, A. K.; Hammerstad, M.; Alling, R. M.; Wildhagen, M.; Sawa, S.; Aalen, R. B.
10.1101/2020.06.02.130120 — evolutionary biology — Posted on 2020-06-04
4561 miR-203 imposes an intrinsic barrier during cellular reprogramming by targeting NFATC2
Salazar-Roa, M.; Martinez-Martinez, S.; Grana Castro, O.; Alvarez-Fernandez, M.; Trakala, M.; Redondo, J. M.; Malumbres, M.
10.1101/2020.06.02.131136 — cell biology — Posted on 2020-06-04
4564 Substitution of nucleotide-sugar by trehalose-dependent glycogen synthesis pathways in Chlamydiales underlines an unusual requirement for storage polysaccharides within obligate intracellular bacteria
Colpaert, M.; Kadouche, D.; Ducatez, M.; Pillonel, T.; Kebbi Beghdadi, C.; Cenci, U.; Huang, B.; Chabi, M.; Maës, E.; Coddeville, B.; Couderc, L.; Touzet, H.; Bray, F.; Tirtiaux, C.; Ball, S.; Greub, G.; Colleoni, C.
10.1101/2020.06.02.131169 — microbiology — Posted on 2020-06-04
4566 Clustering of loci controlling species differences in chemical bouquets of sympatric Heliconius butterflies
Byers, K. J. R. P.; Darragh, K.; Fernanda Garza, S.; Abondano Almeida, D.; Warren, I. A.; Rastas, P. M. A.; Merrill, R. M.; Schulz, S.; McMillan, W. O.; Jiggins, C. D.
10.1101/2020.06.03.131557 — evolutionary biology — Posted on 2020-06-04
4567 Chromatin remodeler Brahma safeguards canalization in cardiac mesoderm differentiation
Hota, S. K.; Blair, A. P.; Rao, K. S.; So, K.; Blotnick, A. M.; Desai, R. V.; Weinberger, L. S.; Kathiriya, I. S.; Bruneau, B. G.
10.1101/2020.06.03.132654 — developmental biology — Posted on 2020-06-04
4568 High-fat diet impacts the colon and its transcriptome in a sex-dependent manner that is modifiable by estrogens
Hases, L.; Archer, A.; Indukuri, R.; Birgersson, M.; Savva, C.; Korach-Andre, M.; Williams, C.
10.1101/2020.06.03.131771 — cell biology — Posted on 2020-06-04
4569 Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion
Chan, K. M. C.; Arthur, A. L.; Morstein, J.; Jin, M.; Bhat, A.; Schlesinger, D.; Son, S.; Stevens, D. A.; Drubin, D. G.; Fletcher, D. A.
10.1101/2020.06.03.130740 — cell biology — Posted on 2020-06-04
4576 MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data
Cmero, M.; Schmidt, B.; Majewski, I. J.; Ekert, P. G.; Oshlack, A.; Davidson, N. M.
10.1101/2020.06.03.131532 — bioinformatics — Posted on 2020-06-04
4577 Distinct gene expression profiles in leukocortical demyelinated white and grey matter areas of Multiple Sclerosis patients
van Wageningen, T. A.; Gerrits, E.; Geleijnse, A.; Brouwer, N.; Geurts, J. J. G.; Eggen, B. J. L.; Boddeke, E. W. G. M.; van Dam, A.-M.
10.1101/2020.06.03.131300 — neuroscience — Posted on 2020-06-04
4579 In situ measurement of intracellular thermal conductivity using heater-thermometer hybrid diamond nanosensor
Sotoma, S.; Zhong, C.; Kah, J. C. Y.; Yamashita, H.; Plakhotnik, T.; Harada, Y.; Suzuki, M.
10.1101/2020.06.03.126789 — cell biology — Posted on 2020-06-04
4581 Modeling cell turning by mechanics at the cell rear
Lee, K.-C.; Allen, G.; Barnhart, E.; Tsuchida, M.; Wilson, C.; Gutierrez, E.; Groisman, A.; Theriot, J.; Mogilner, A.
10.1101/2020.06.03.132456 — biophysics — Posted on 2020-06-04
4585 Lipin-1 regulates lipid catabolism in pro-resolving macrophages.
Schilke, R. M.; Blackburn, C. M. R.; Rao, S.; Krzywanski, D. M.; Finck, B. N.; Woolard, M. D.
10.1101/2020.06.03.121293 — immunology — Posted on 2020-06-03
4587 Scc2 and Scc3 promote distinct modes of topological association between cohesin and DNA
Collier, J. E.; Brunet-Roig, M.; Yatskevich, S.; Petela, N. J.; Metson, J.; Voulgaris, M.; Lee, B.-G.; Lowe, J.; nasmyth, k. a.
10.1101/2020.06.03.132233 — biochemistry — Posted on 2020-06-03
4588 Rab2 drives axonal transport of dense core vesicles and lysosomal organelles
Lund, V. K.; Lycas, M. D.; Schack, A.; Andersen, R. C.; Gether, U.; Kjaerulff, O.
10.1101/2020.06.03.131672 — neuroscience — Posted on 2020-06-03
4592 Identification of repurposable cytoprotective drugs for Vanishing White Matter Disease
Ng, N.; Cabral-da-Silva, M. C.; Maksour, S.; Berg, T.; Engel, M.; Silva, D. M.; Do-Ha, D.; Lum, J. S.; Sanz Munoz, S.; Suarez-Bosche, N.; Stevens, C. H.; Ooi, L.
10.1101/2020.06.02.131052 — neuroscience — Posted on 2020-06-03
4595 CRTC1-MAML2 Establishes a PGC1α-IGF1 Circuit that Confers Vulnerability to PPARγ Inhibition
Musicant, A. M.; Parag-Sharma, K.; Gong, W.; Sengupta, M.; Chatterjee, A.; Henry, E. C.; Tsai, Y.-H.; Hayward, M.; Sheth, S.; Betancourt, R.; Hackman, T.; Padilla, R. J.; Parker, J. S.; Giudice, J.; Flaveny, C. A.; Hayes, D. N.; Amelio, A. L.
10.1101/2020.06.03.129668 — cancer biology — Posted on 2020-06-03
4596 Ubiquilin proteins regulate EGFR levels and activity in lung adenocarcinoma cells
Kurlawala, Z.; Saurabh, K.; Dunaway, R.; Shah, P.; Siskind, L. J.; Beverly, L. J.
10.1101/2020.06.03.131888 — cancer biology — Posted on 2020-06-03
4597 Mutations in BBS2 Cause Apparent Nonsyndromic Retinitis Pigmentosa
DeBenedictis, M.; Fogerty, J.; Pauer, G.; Chiang, J.; Hagstrom, S.; Traboulsi, E. I.; Perkins, B.
10.1101/2020.06.03.130518 — genetics — Posted on 2020-06-03
4598 Designer protein assemblies with tunable phase diagrams in living cells
Heidenreich, M.; Georgeson, J.; Locatelli, E.; Rovigatti, L.; Nandi, S. K.; Steinberg, A.; Nadav, Y.; Shimoni, E.; Safran, S. A.; Doye, J. P. K.; Levy, E. D.
10.1101/2020.06.03.131433 — synthetic biology — Posted on 2020-06-03
4599 Distinct growth stages shaped by an interplay of deterministic and neutral processes are indispensable for functional anammox biofilms
Niederdorfer, R.; Fragner, L.; Yuan, L.; Hausherr, D.; Wei, J.; Magyar, P. M.; Joss, A.; Ju, F.; Buergmann, H.
10.1101/2020.06.03.131896 — microbiology — Posted on 2020-06-03
4603 Lactoferrin retargets adenoviruses to TLR4 to induce an abortive NLRP3-associated pyroptotic response in human dendritic cells
Cheneau, C.; Eichholz, K.; Tran, T. H.; Tran, T. T. P.; Paris, O.; Henriquet, C.; Pugniere, M.; Kremer, E. J.
10.1101/2020.06.03.131664 — immunology — Posted on 2020-06-03
4607 Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping
Credle, J. J.; Robinson, M.; Gunn, J.; Monaco, D.; Sie, B.; Tchir, A. L.; Hardick, J.; Zheng, X.; Shaw-Saliba, K.; Rothman, R.; Eshleman, S.; Pekosz, A.; Hansen, K.; Mostafa, H.; Steinegger, M.; Larman, H. B.
10.1101/2020.06.03.130591 — pathology — Posted on 2020-06-03
4608 Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients
Andres, C.; Garcia-Cehic, D.; Gregori, J.; Pinana, M.; Rodriguez-Frias, F.; Guerrero, M.; Esperalba, J.; Rando, A.; Goterris, L.; Codina, M. G.; Quer, S.; Martin, M. C.; Campins, M.; Ferrer, R.; Almirante, B.; Esteban, J. I.; Pumarola, T.; Anton, A.; Quer, J.
10.1101/2020.06.03.129585 — microbiology — Posted on 2020-06-03
4609 Analyzing hCov genome sequences: Applying Machine Intelligence and beyond
Sawmya, S.; Saha, A.; Tasnim, S.; Anjum, N.; Toufikuzzaman, M.; Rafid, A. H. M.; Rahman, M. S.; Rahman, M. S.
10.1101/2020.06.03.131987 — bioinformatics — Posted on 2020-06-03
4612 Enteropathy-induced regulatory T cells inhibit intestinal CD4+ T cell responses against oral vaccines
Bhattacharjee, A.; Burr, A. H. P.; Overacre-Delgoffe, A. E.; Tometich, J. T.; Yang, D.; Huckestein, B. R.; Linehan, J. L.; Spencer, S. P.; Hall, J. A.; Harrison, O. J.; Morais da Fonseca, D.; Norton, E. B.; Belkaid, Y.; Hand, T. W.
10.1101/2020.06.03.130831 — immunology — Posted on 2020-06-03
4615 TGN/EE SNARE protein SYP61 is ubiquitinated and required for carbon/nitrogen-nutrient responses in Arabidopsis
Hasegawa, Y.; Huarancca Reyes, T.; Uemura, T.; Fujimaki, A.; Luo, Y.; Morita, Y.; Saeki, Y.; Baral, A.; Maekawa, S.; Yasuda, S.; Mukuta, K.; Fukao, Y.; Tanaka, K.; Nakano, A.; Bhalerao, R. P.; Sato, T.; Yamaguchi, J.
10.1101/2020.06.03.131094 — plant biology — Posted on 2020-06-03
4616 Using a bistable animal opsin for switchable and scalable optogenetic inhibition of neurons
Rodgers, J.; Bano-Otalora, B.; Belle, M. D.; Paul, S.; Hughes, R.; Wright, P.; McDowell, R.; Milosavljevic, N.; Orlowska-Feuer, P.; Martial, F.; Wynne, J.; Ballister, E. R.; Storchi, R.; Allen, A. E.; Brown, T.; Lucas, R. J.
10.1101/2020.06.03.129627 — neuroscience — Posted on 2020-06-03
4622 Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans
Mühlhausen, S.; Schmitt, H. D.; Plessmann, U.; Mienkus, P.; Sternisek, P.; Perl, T.; Weig, M.; Urlaub, H.; Bader, O.; Kollmar, M.
10.1101/2020.06.03.131292 — genomics — Posted on 2020-06-03
4623 Denisovan ancestry and population history of early East Asians
Massilani, D.; Skov, L.; Hajdinjak, M.; Gunchinsuren, B.; Tseveendorj, D.; Yi, S.; Lee, J.; Nagel, S.; Nickel, B.; Deviese, T.; Higham, T.; Meyer, M.; Kelso, J.; Peter, B. M.; Paabo, S.
10.1101/2020.06.03.131995 — evolutionary biology — Posted on 2020-06-03
4624 Modelling live fuel moisture content at leaf and canopy scale under extreme drought using SurEau-Ecos, a lumped plant hydraulic model
Martin-StPaul, N.; Ruffault, J.; Blackmann, C.; Cochard, H.; De Caceres, M.; Delzon, S.; Dupuy, J.-L.; Fargeon, H.; Lamarque, L.; Moreno, M.; Parsons, R.; Pimont, F.; Ourcival, J.-M.; Torres-Ruiz, J.; Limousin, J.-M.
10.1101/2020.06.03.127167 — ecology — Posted on 2020-06-03
4625 Purification of age-distinct insulin secretory granules through antigen restriction using the CLIP-tag
Neukam, M.; Ganss, K.; Vasiljevic, J.; Broichhagen, J.; Johnsson, K.; Kurth, T.; Solimena, M.
10.1101/2020.06.03.103770 — cell biology — Posted on 2020-06-03
4627 Liver-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice
Singh, A. K.; Chaube, B.; Canfran-Duque, A.; Zhang, X.; Price, N. L.; Aryal, B.; Sun, J.; Citrin, K. M.; Rotllan, N.; Lee, R.; Suarez, Y.; Fernandez-Hernando, C.
10.1101/2020.06.02.130922 — physiology — Posted on 2020-06-03
4628 CB1 receptor signaling modulates amygdalar plasticity during context-cocaine memory reconsolidation to promote subsequent cocaine seeking
Higginbotham, J. A.; Wang, R.; Richardson, B. D.; Shiina, H.; Tan, S. M.; Presker, M. A.; Rossi, D. J.; Fuchs, R. A.
10.1101/2020.06.02.130419 — neuroscience — Posted on 2020-06-03
4634 Therapy-induced transdifferentiation promotes glioma growth independent of EGFR signaling
Oh, H.; Hwang, I.; Wu, L.; Cao, D.; Yao, J.; Ying, H.; Li, J. Y.; Yao, Y.; Hu, B.; Wang, Q.; Zheng, H.; Paik, J.
10.1101/2020.06.02.130948 — cancer biology — Posted on 2020-06-03
4635 Development and Characterization of Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases
Baschnagel, A. M.; Kaushik, S.; Durmaz, A.; Goldstein, S.; Ong, I. M.; Abel, L.; Clark, P. A.; Leal, T.; Buehler, D.; Iyer, G.; Scott, J. G.; Kimple, R. J.
10.1101/2020.06.02.130062 — cancer biology — Posted on 2020-06-03
4637 Estimating Microbial Interaction Network:Zero-inated Latent Ising Model Based Approach
Zhou, J.; Viles, W. D.; Lu, B.; Li, Z.; Madan, J. C.; Karagas, M. R.; Gui, J.; Hoen, A. G.
10.1101/2020.06.02.130914 — bioinformatics — Posted on 2020-06-03
4641 Molecular Basis of Far-red Sensing in Cyanobacteriochrome
Bandara, S.; Rockwell, N. C.; Zeng, X.; Ren, Z.; Wang, C.; Shin, H.; Martin, S.; Moreno, M.; Lagarias, J. C.; Yang, X.
10.1101/2020.06.02.130930 — biochemistry — Posted on 2020-06-03
4642 CASTLE: Cell Adhesion with Supervised Training and Learning Environment
Gilbert, S. G.; Krautter, F.; Cooper, D. G.; Chimen, M.; Iqbal, A. J.; Spill, F.
10.1101/2020.06.02.130708 — immunology — Posted on 2020-06-03
4644 Balancing signal and photoperturbation in multiphoton light-sheet microscopy by optimizing laser pulse frequency
Maioli, V.; Boniface, A.; Mahou, P.; Ferrer Ortas, J.; Abdeladim, L.; Beaurepaire, E.; Supatto, W.
10.1101/2020.06.02.130377 — biophysics — Posted on 2020-06-03
4645 Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α
Mann, S.; Hadad, N.; Nelson, M.; Rothman, A.; Sathiaseelan, R.; Ali-Mondal, S.; Agbaga, M.-P.; Unnikrishnan, A.; Malayannan, S.; Hawse, J.; Huffmam, D.; Freeman, W. M.; Stout, M. B.
10.1101/2020.06.02.130674 — physiology — Posted on 2020-06-03
4646 Intestinal-derived FGF15 preserves muscle and bone mass following sleeve gastrectomy
Bozadjieva Kramer, N.; Shin, J. H.; Shao, Y.; Gutierrez-Aguilar, R.; Li, Z.; Heppner, K. M.; Chiang, S.; Vargo, S. G.; Granger, K.; Sandoval, D. A.; MacDougald, O.; Seeley, R.
10.1101/2020.06.02.130278 — physiology — Posted on 2020-06-03
4647 Dopamine Release Neuroenergetics in Mouse Striatal Slices
Msackyi, M.; Chen, Y.; Tsering, W.; Wang, N.; Zhao, J.; Zhang, H.
10.1101/2020.06.02.130328 — neuroscience — Posted on 2020-06-03
4649 Microbiota control of maternal behavior regulates early postnatal growth of offspring
Lee, Y. M.; Wallace, M.; Gengatharan, J. M.; Furst, A. J.; Bode, L.; Metallo, C. M.; Ayres, J. S.
10.1101/2020.06.02.130682 — physiology — Posted on 2020-06-03
4650 Multivalent lipid targeting by the calcium-independent C2A domain of Slp-4/granuphilin
Alnaas, A. A.; Watson-Siriboe, A.; Tran, S.; Negussie, M.; Henderson, J. A.; Osterberg, J. R.; Lee Chon, N.; Oviedo, J.; Lyakhova, T.; Michel, C.; Reisdorph, N.; Reisdorph, R.; Shearn, C. T.; Lin, H.; Knight, J. D.
10.1101/2020.05.29.123596 — biophysics — Posted on 2020-06-03
4651 Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer's disease
Yang, H. S.; Onos, K. D.; Choi, K.; Keezer, K. J.; Skelly, D. A.; Carter, G. W.; Howell, G. R.
10.1101/2020.06.02.130237 — neuroscience — Posted on 2020-06-03
4655 Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling
Lin, C.; Blessing, A. M.; Pulliam, T. L.; Shi, Y.; Wilkenfeld, S. R.; Han, J. J.; Murray, M. M.; Pham, A. H.; Duong, K.; Brun, S. N.; Shaw, R. J.; Ittmann, M. M.; Frigo, D. E.
10.1101/2020.06.02.130088 — cancer biology — Posted on 2020-06-03
4658 Mitotic retention of H3K27 acetylation promotes rapid topological and transcriptional resetting of stem cell-related genes and enhancers upon G1 entry
Pelham-Webb, B.; Polyzos, A.; Wojenski, L.; Kloetgen, A.; Li, J.; Di Giammartino, D. C.; Core, L.; Tsirigos, A.; Apostolou, E.
10.1101/2020.06.02.130104 — molecular biology — Posted on 2020-06-03
4662 A globally threatened shark, Carcharias taurus, shows no population decline in South Africa
Klein, J. D.; Bester-van der Merwe, A. E.; Dicken, M. L.; Emami-Khoyi, A.; Mmonwa, K. L.; Teske, P. R.
10.1101/2020.06.02.130005 — genetics — Posted on 2020-06-03
4663 AutoNeuriteJ: An ImageJ plugin for measurement and classification of neuritic extensions
Boulan, B.; Beghin, A.; Ravanello, C.; Deloulme, J.-C.; Gory-Faure, S.; Andrieux, A.; Brocard, J.; Denarier, E.
10.1101/2020.05.29.123000 — bioinformatics — Posted on 2020-06-03
4664 Temporal evolution and adaptation of SARS-COV 2 codon usage
Dilucca, M.; Forcelloni, S.; Georgakilas, A. G.; Giansanti, A.; Pavlopoulou, A.
10.1101/2020.05.29.123976 — genomics — Posted on 2020-06-03
4666 Context-dependent functional compensation between Ythdf m6A readers
Lasman, L.; Krupalnik, V.; Geula, S.; Zerbib, M.; Viukov, S.; Mor, N.; Aguilera, A.; Mizrahi, O.; Shashank, S.; Nachshon, A.; Schneir, D.; Aigner, S.; Shankar, A.; Mueller, J.; Stern-Ginossar, N.; Yeo, G. W.; Novershtern, N.; Hanna, J. H.
10.1101/2020.06.03.131441 — developmental biology — Posted on 2020-06-03
4669 Pattern-recognition receptors are required for NLR-mediated plant immunity
Yuan, M.; Jiang, Z.; Bi, G.; Nomura, K.; Liu, M.; He, S. Y.; Zhou, J.-M.; Xin, X.-F.
10.1101/2020.04.10.031294 — plant biology — Posted on 2020-06-03
4672 Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis
Tsuchiya, H.; Ota, M.; Sumitomo, S.; Ishigaki, K.; Suzuki, A.; Sakata, T.; Tsuchida, Y.; Inui, H.; Hirose, J.; Kochi, Y.; Kadono, Y.; Shirahige, K.; Tanaka, S.; Yamamoto, K.; Fujio, K.
10.1101/861781 — immunology — Posted on 2020-06-03
4673 Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis
Wu, J.; Song, D.; Li, Z.; Guo, B.; Xiao, Y.; Liu, W.; Liang, L.; Chen, Y.; Feng, C.; Gao, T.; Wang, Z.; Wen, J.; Yang, S.; Liu, P.; Li, Y.; Wang, L.; Wang, Y.; Peng, L.; Hu, Z.; Stacey, G. N.; Feng, G.; Li, W.; Huo, Y.; Jin, R.; Shyh-Chang, N.; Zhou, Q.; Wang, L.; Hu, B.; Dai, H.; Hao, J.
10.1101/2020.04.15.042119 — cell biology — Posted on 2020-06-03
4675 Dual acting small-Molecule inhibitors targeting Mycobacterial DNA replication
Singh, M.; Ilic, S.; Tam, B.; Ben-Ishay, Y.; Sherf, D.; Pappo, D.; Akabayov, B.
10.1101/561506 — biochemistry — Posted on 2020-06-03
4676 Human SYNGAP1 Regulates the Development of Neuronal Activity by Controlling Dendritic and Synaptic Maturation
Llamosas, N.; Arora, V.; Vij, R.; Klinik, M.; Bijoch, L.; Rojas, C.; Reich, A.; Sridharan, B.; Willems, E.; Piper, D. R.; Scampavia, L.; Spicer, T. P.; Miller, C. A.; Holder, J. L.; Rumbaugh, G.
10.1101/2020.06.01.127613 — neuroscience — Posted on 2020-06-03
4678 The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Santosh, V.; Musayev, F. N.; Jaiswal, R.; Zarate-Perez, F.; Vandewinkel, B.; Dierckx, C.; Endicott, M.; Sharifi, K.; Dryden, K.; Henckaerts, E.; Escalante, C. R.
10.1101/2020.06.02.126235 — biochemistry — Posted on 2020-06-03
4681 Analysis of coagulation factor IX in bioreactor cell culture medium predicts yield and quality of the purified product
Zacchi, L. F.; Roche Recinos, D.; Pegg, C. L.; Phung, T. K.; Napoli, M.; Aitken, C.; Sandford, V.; Mahler, S. M.; Lee, Y. Y.; Schulz, B. L.; Howard, C. B.
10.1101/2020.06.03.131177 — biochemistry — Posted on 2020-06-03
4683 Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
Oosterheert, W.; Xenaki, K. T.; Neviani, V.; Pos, W.; Doulkeridou, S.; Manshande, J.; Pearce, N. M.; Kroon-Batenburg, L. M. J.; Lutz, M.; van Bergen en Henegouwen, P. M. P.; Gros, P.
10.1101/2020.06.02.130047 — biophysics — Posted on 2020-06-03
4685 Optimized pseudotyping conditions for the SARS-COV2 Spike glycoprotein
Johnson, M. C.; Lyddon, T. D.; Suarez, R.; Salcedo, B.; LePique, M.; Graham, M.; Ricana, C.; Robinson, C.; Ritter, D. G.
10.1101/2020.05.28.122671 — microbiology — Posted on 2020-06-03
4687 Evaluating single-cell cluster stability using the Jaccard similarity index
Tang, M.; Kaymaz, Y.; Logeman, B.; Eichhorn, S.; Liang, Z. S.; Dulac, C.; Sackton, T. B.
10.1101/2020.05.26.116640 — bioinformatics — Posted on 2020-06-03
4688 The Homo-Edit Distance Problem
Brand, M.; Tran, N. K.; Spohr, P.; Schrinner, S.; Klau, G. W.
10.1101/2020.05.27.118273 — bioinformatics — Posted on 2020-06-03
4689 Presynaptic precursor vesicles originate from the trans-Golgi network, promoted by the small GTPase RAB2
Goetz, T. W. B.; Puchkov, D.; Luetzkendorf, J.; Nikonenko, A. G.; Quentin, C.; Lehmann, M.; Sigrist, S. J.; Petzoldt, A. G.
10.1101/2020.06.02.128991 — neuroscience — Posted on 2020-06-03
4691 The Temporal Relationships between White Matter Hyperintensities, Neurodegeneration, Amyloid β, and Cognition
Dadar, M.; Camicioli, R.; Duchesne, S.; Collins, D. L.; for the Alzheimers Disease Neuroimaging Initiative,
10.1101/2020.05.27.119586 — neuroscience — Posted on 2020-06-03
4692 Risk factors associated with mortality in hospitalized patients with SARS-CoV-2 infection. A prospective, longitudinal, unicenter study in Reus, Spain
Iftimie, S.; Lopez-Azcona, A. F.; Vicente-Miralles, M.; Descarrega-Reina, R.; Hernandez-Aguilera, A.; Riu, F.; Simo, J. M.; Garrido, P.; Joven, J.; Camps, J.; Castro, A.
10.1101/2020.05.29.122986 — microbiology — Posted on 2020-06-03
4693 Comprehensive and Integrated Genomic Characterization of Human Immunome in Cancer
Li, Y.; Triplett, T.; Burgman, B.; Sun, M.; McGrail, D. J.; Qi, D.; Shukla, S.; Wu, E.; Wu, C. J.; Capasso, A.; Eckhardt, S. G.; Georgiou, G.; Li, B.; Sahni, N.; Yi, S. S.
10.1101/2020.06.02.128884 — immunology — Posted on 2020-06-03
4696 ANGPTL4 from adipose, but not liver, is responsible for regulating plasma triglyceride partitioning
Spitler, K. M.; Shetty, S. K.; Cushing, E. M.; Sylvers-Davie, K. L.; Davies, B. S. J.
10.1101/2020.06.02.106815 — physiology — Posted on 2020-06-03
4697 Extra-hypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance
Duque-Wilckens, N.; Torres, L.; Yokoyama, S.; Minie, V.; Tran, A.; Petkova, S.; Hao, R.; Ramos-Maciel, S.; Rioa, R.; Jackson, K.; Flores-Ramirez, F.; Garcia-Carachure, I.; Pesavento, P. A.; Iniguez, S.; Grinevich, V.; Trainor, B. C.
10.1101/2020.06.02.129981 — neuroscience — Posted on 2020-06-03
4698 Molecular determinants of liquid demixing and amyloidogenesis in human CPEB3
Ramirez de Mingo, D.; Lopez-Garcia, P.; Hervas, R.; Laurents, D. V.; Carrion-Vazquez, M.
10.1101/2020.06.02.129783 — neuroscience — Posted on 2020-06-03
4704 Loss of coiled-coil protein Cep55 impairs abscission processes and results in p53-dependent apoptosis in developing cortex
Little, J. N.; McNeely, K. C.; Michel, N.; Bott, C. J.; Lettieri, K. S.; Hecht, M. R.; Martin, S. A.; Dwyer, N. D.
10.1101/2020.06.02.129346 — developmental biology — Posted on 2020-06-03
4706 Masserstein: robust linear deconvolution by optimal transport
Ciach, M. A.; Miasojedow, B.; Skoraczynski, G.; Majewski, S.; Startek, M.; Valkenborg, D.; Gambin, A.
10.1101/2020.06.02.129858 — bioinformatics — Posted on 2020-06-03
4707 Extended Application of Genomic Selection to Screen Multi-Omics Data for Prognostic Signatures of Prostate Cancer
Li, R.; Wang, S.; Cui, Y.; Qu, H.; Chater, J. M.; Zhang, L.; Wei, J.; Wang, M.; Xu, Y.; Yu, L.; Lu, J.; Feng, Y.; Zhou, R.; Huang, Y.; Ma, R.; Zhu, J.; Zhong, W.; Jia, Z.
10.1101/2020.06.02.115816 — bioinformatics — Posted on 2020-06-03
4708 Tracking Adoptive T Cell Therapy Using Magnetic Particle Imaging
Rivera-Rodriguez, A.; Hoang-Minh, L. B.; Chiu-Lam, A.; Sarna, N.; Marrero-Morales, L.; Mitchell, D. A.; Rinaldi, C.
10.1101/2020.06.02.128587 — bioengineering — Posted on 2020-06-03
4709 Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in idiopathic pulmonary fibrosis
Matera, D. L.; DiLillo, K. M.; Smith, M. R.; Davidson, C. D.; Parikh, R.; Said, M.; Wilke, C. A.; Lombaert, I. M.; Arnold, K. B.; Moore, B. B.; Baker, B. M.
10.1101/2020.06.02.129718 — bioengineering — Posted on 2020-06-03
4711 NON-AVIAN DINOSAUR EGGSHELL CALCITE CONTAINS ANCIENT, ENDOGENOUS AMINO ACIDS
Saitta, E. T.; Vinther, J.; Crisp, M. K.; Abbott, G. D.; Kaye, T. G.; Pittman, M.; Bull, I.; Fletcher, I.; Chen, X.; Collins, M. J.; Sakalauskaite, J.; Mackie, M.; Dal Bello, F.; Dickinson, M. R.; Stevenson, M. A.; Donohoe, P.; Heck, P. R.; Demarchi, B.; Penkman, K. E. H.
10.1101/2020.06.02.129999 — paleontology — Posted on 2020-06-03
4713 Getting stuck in a rut as an emergent feature of a dynamic decision-making system
Warburton, M.; Brookes, J.; Hasan, M.; Leonetti, M.; Dogar, M.; Wang, H.; Cohn, A.; Mushtaq, F.; Mon-Williams, M.
10.1101/2020.06.02.127860 — neuroscience — Posted on 2020-06-03
4715 Monocyte Subsets with High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8
Das, A.; Wang, X.; Kang, J.; Coulter, A.; Shetty, A. C.; Bachu, M.; Brooks, S.; Dell'Orso, S.; Foster, B. L.; Fan, X.; Ozato, K.; Somerman, M.; Thumbigere Math, V.
10.1101/2020.06.02.126284 — immunology — Posted on 2020-06-03
4716 Paleoclimate and current climate collectively shape the phylogenetic and functional diversity of trees worldwide
Guo, W.-Y.; Serra-Diaz, J. M.; Schrodt, F.; Eiserhardt, W. L.; Maitner, B. S.; Merow, C.; Violle, C.; Blach-Overgaard, A.; Zhang, J.; Anand, M.; Belluau, M.; Bruun, H. H.; Byun, C.; Catford, J. A.; Cerabolini, B. E. L.; Chacón-Madrigal, E.; Ciccarelli, D.; Cornelissen, J. H. C.; Dang-Le, A. T.; de Frutos, A.; Dias, A. S.; Giroldo, A. B.; Hattingh, W.; He, T.; Hietz, P.; Hough-Snee, N.; Jansen, S.; Kattge, J.; klein, t.; Komac, B.; Kraft, N.; Kramer, K.; Lavorel, S.; Lusk, C. H.; Martin, A. R.; Mencuccini, M.; Michaletz, S. T.; Minden, V.; Mori, A. S.; Niinemets, Ülo; Onoda, Y.; Onste
10.1101/2020.06.02.128975 — ecology — Posted on 2020-06-03
4717 CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer
Tallon de Lara, P.; Castanon Cuadrado, H.; Vermeer, M.; Nunez, N.; Silina, K.; Sobottka, B.; Urdinez, J.; Cecconi, V.; Movahedian Attar, F.; Hiltbrunner, S.; Glarner, I.; Moch, H.; Tugues, S.; Becher, B.; van den Broek, M.
10.1101/2020.06.02.126037 — cancer biology — Posted on 2020-06-03
4719 Online milk composition analysis with an on-farm near-infrared sensor
Diaz-Olivares, J. A.; Adriaens, I.; Stevens, E.; Saeys, W.; Aernouts, B.
10.1101/2020.06.02.129742 — bioengineering — Posted on 2020-06-03
4721 Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5
Wang, Z.; Vermij, S. H.; Sottas, V.; Shestak, A.; Ross-Kaschitza, D.; Zaklyazminskaya, E. V.; Hudmon, A.; Pitt, G. S.; Rougier, J.-S.; Abriel, H.
10.1101/2020.06.02.129288 — physiology — Posted on 2020-06-03
4726 Optimizing nucleic acid extraction and transcriptome evaluation from low-input, fixed clinical samples
Campbell, K. M.; Medina, E.; Baselga Carretero, I.; Teper, Y.; Elumalai, R.; Miller, R.; Pal, K.; Pitzer, J.; Daviso, E.; Carstens, C.; Laugharn, J.; Hugo, W.; Chen, J. M.; Vega-Crespo, A.; Jilani, S.; Garcilazo, I. P.; Dong, L.; Li, X.; Hu-Lieskovan, S.; Ribas, A.
10.1101/2020.06.02.122150 — genomics — Posted on 2020-06-03
4727 Ecological differentiation and incipient speciation in the fungal pathogen causing rice blast
Thierry, M.; Milazzo, J.; Adreit, H.; Ravel, S.; Borron, S.; Sella, V.; Ioos, R.; Fournier, E.; Tharreau, D.; Gladieux, P.
10.1101/2020.06.02.129296 — evolutionary biology — Posted on 2020-06-03
4729 Patient Similarity Network of Newly Diagnosed Multiple Myeloma Identifies Patient Sub-groups with Distinct Genetic Features and Clinical Implications
Bhalla, S.; Melnekoff, D. T.; Keats, J.; Onel, K.; Madduri, D.; Richter, J.; Richard, S.; Chari, A.; Cho, H. J.; Dudley, J. T.; Jagannath, S.; Lagana, A.; Parekh, S.
10.1101/2020.06.02.129767 — cancer biology — Posted on 2020-06-03
4730 Structural basis for polarized elongation of actin filaments
Zsolnay, V.; Katkar, H. H.; Chou, S. Z.; Pollard, T. D.; Voth, G. A.
10.1101/2020.06.02.129940 — biophysics — Posted on 2020-06-03
4732 Development of an absolute assignment predictor for triple-negative breast cancer subtyping using machine learning approaches
Ben Azzouz, F.; Michel, B.; Lasla, H.; Gouraud, W.; Francois, A.-F.; Girka, F.; Lecointre, T.; Guerin-Charbonnel, C.; Juin, P. P.; Campone, M.; Jezequel, P.
10.1101/2020.06.02.129544 — bioinformatics — Posted on 2020-06-03
4737 The burden of rare protein-truncating genetic variants on human lifespan
Liu, J. Z.; Chen, C.-Y.; Tsai, E.; Whelan, C. D.; Sexton, D.; John, S.; Runz, H.
10.1101/2020.06.02.129908 — genetics — Posted on 2020-06-03
4738 Sequence diversity and evolution of an iflavirus family associated with ticks
Daveu, R.; Hervet, C.; Sigrist, L.; Sassera, D.; Jex, A.; Labadie, K.; Aury, J.-M.; Plantard, O.; Rispe, C.
10.1101/2020.06.02.129551 — evolutionary biology — Posted on 2020-06-03
4743 Mucosal immune stimulation with HSV-2 and polyICLC boosts control of viremia in SIVΔNef vaccinated rhesus macaques with breakthrough SIV infection
Aravantinou, M.; Mizenina, O.; Brill, T.; Kenney, J.; Timmons, C.; Frank, I.; Gettie, A.; Grasperge, B.; Blanchard, J.; Salazar, A.; Lifson, J. D.; Robbiani, M.; Derby, N.
10.1101/2020.06.02.129494 — immunology — Posted on 2020-06-02
4748 Optimizing the molecular diagnosis of Covid-19 by combining RT-PCR and a pseudo-convolutional machine learning approach to characterize virus DNA sequences
Gomes, J. C.; Silva, L. H. d. S.; Ferreira, J.; F. Junior, A. A.; Rocha, A. L. d. S.; Castro, L.; da Silva, N. R. C.; Fernandes, B. J. T.; dos Santos, W. P.
10.1101/2020.06.02.129775 — bioinformatics — Posted on 2020-06-02
4749 Discovery of a small molecule having both potent anti-fibrotic and anti-inflammatory capabilities
Kim, H.-S.; Meang, M. K.; Ham, M.-J.; Lee, J. Y.; Seong, B.; Yoon, H. S.; Kim, I.-H.; Youn, B.-S.
10.1101/770404 — pharmacology and toxicology — Posted on 2020-06-02
4750 Altering PRC2 activity partially suppresses ddm1 mutant phenotypes in Arabidopsis
Rougee, M.; Quadrana, L.; Zervudacki, J.; Colot, V.; Navarro, L.; Deleris, A.
10.1101/782219 — molecular biology — Posted on 2020-06-02
4751 Geographic heterogeneity in Anopheles albimanus microbiota is lost within one generation of laboratory colonization
Dada, N.; Benedict, A. C.; Lopez, F.; Lol, J. C.; Sheth, M.; Dzuris, N.; Padilla, N.; Lenhart, A.
10.1101/2020.06.02.129619 — microbiology — Posted on 2020-06-02
4753 An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
Hanke, L.; Perez Vidakovics, M. L.; Sheward, D.; Das, H.; Schulte, T.; Moliner Morro, A.; Corcoran, M.; Achour, A.; Karlsson Hedestam, G.; Hällberg, B. M.; Murrell, B.; McInerney, G. M.
10.1101/2020.06.02.130161 — microbiology — Posted on 2020-06-02
4754 Insights into the structure and role of seed-borne bacteriome during maize germination
Santos, L. F.; Souta, J.; Soares, C. d. P.; da Rocha, L. O.; Santos, M. L. C.; Grativol, C.; Roesch, L.; Olivares, F. L.
10.1101/2020.06.02.130856 — microbiology — Posted on 2020-06-02
4756 Identification of long regulatory elements in the genome of Plasmodium falciparum and other eukaryotes
Menichelli, C.; Guitard, V.; Martins, R. M.; Lebre, S.; Lopez-Rubio, J.-J.; Lecellier, C. H.; Brehelin, L.
10.1101/2020.06.02.130468 — bioinformatics — Posted on 2020-06-02
4757 Structure of MlaFEDB lipid transporter reveals an ABC exporter fold and two bound phospholipids
Coudray, N.; Isom, G. L.; MacRae, M. R.; Saiduddin, M. N.; Bhabha, G.; Ekiert, D. C.
10.1101/2020.06.02.129247 — biochemistry — Posted on 2020-06-02
4760 STAT3 Serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
Balic, J.; Albargy, H.; Luu, K.; Kirby, F.; Jayasekara, W.; Mansell, F.; Garama, D.; Baschuk, N.; De Nardo, D.; Louis, C.; Humphries, F.; Fitzgerald, K. A.; Latz, E.; Gough, D.; Mansell, A.
10.1101/2020.06.02.130716 — immunology — Posted on 2020-06-02
4762 Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Wang, X.; Lv, Z.; Deng, Y.-Q.; Ye, Q.; Cao, L.; Sun, C.-Y.; Fan, C.; Huang, W.; Sun, S.; Sun, Y.; Zhu, L.; Chen, Q.; Wang, N.; Nie, J.; Cui, Z.; Zhu, D.; Shaw, N.; Li, X.-F.; Li, Q.; Xie, L.; Wang, Y.; Rao, Z.; Qin, C.-F.
10.1101/2020.06.02.129098 — biophysics — Posted on 2020-06-02
4763 A validated and interpretable predictive model of cruzain inhibitors
Rosas-Jimenez, J. G.; Garcia-Revilla, M. A.; Madariaga-Mazon, A.; Martinez-Mayorga, K.
10.1101/2020.06.02.129411 — biophysics — Posted on 2020-06-02
4768 HiDRA-seq: High-Throughput SARS-CoV-2 Detection by RNA Barcoding and Amplicon Sequencing
Yanguez, E.; White, G.; Kreutzer, S.; Opitz, L.; Poveda, L.; Sykes, T.; Moccia, M. D.; Aquino, C.; Schlapbach, R.
10.1101/2020.06.02.130484 — genomics — Posted on 2020-06-02
4769 Real-time tracking of Tomato brown rugose fruit virus (ToBRFV) outbreaks in the Netherlands using Nextstrain
van de Vossenberg, B. T. L. H.; Visser, M.; Bruinsma, M.; Koenraadt, H. M. S.; Westenberg, M.; Botermans, M.
10.1101/2020.06.02.129395 — evolutionary biology — Posted on 2020-06-02
4770 Evaluation of a large-scale flow manipulation to the upper San Francisco Estuary: Response of habitat conditions for an endangered native fish
Sommer, T.; Hartman, R.; Koller, M.; Koohafkan, M.; Conrad, J. L.; MacWilliams, M.; Bever, A.; Burdi, C.; Beakes, M.
10.1101/2020.06.02.129429 — ecology — Posted on 2020-06-02
4772 In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome
Taher, H.; Mahyari, E.; Kreklywich, C.; Uebelhoer, L. S.; McArdle, M. R.; Moström, M. J.; Bhusari, A.; Nekorchuk, M.; Whitmer, T.; Scheef, E. A.; Sprehe, L. M.; Roberts, D.; Hughes, C. M.; Jackson, K. A.; Selseth, A. N.; Ventura, A. B.; Yue, Y.; Schmidt, K. A.; Shao, J.; Edlefsen, P. T.; Smedley, J.; Stanton, R. J.; Axthelm, M. K.; Estes, J. D.; Hansen, S. G.; Kaur, A.; Barry, P. A.; Bimber, B. N.; Picker, L. J.; Streblow, D. N.; Früh, K.; Malouli, D.
10.1101/2020.06.02.129486 — microbiology — Posted on 2020-06-02
4773 Species composition and risk of transmission of Aedes-borne arboviruses around some Yellow hotspot areas in Northern Ghana
Joannides, J.; Dzodzomenyo, M.; Azerigyik, F.; Agbosu, E. E.; Pratt, D.; Nyarkoh, J. O.; Pwalia, R.; Amlalo, G. K.; Appawu, M.; Takashi, H.; Iwanaga, S.; Buchwald, A.; Rochford, R.; Boakye, D.; Koram, K.; Bonney, K.; Dadzie, S.
10.1101/2020.06.02.129460 — ecology — Posted on 2020-06-02
4775 Microglia dysfunction caused by the loss of Rhoa disrupts neuronal physiology and leads to neurodegeneration
Socodato, R.; Portugal, C. C.; Canedo, T.; Rodrigues, A.; Almeida, T. O.; Henriques, J.; Vaz, S. H.; Magalhaes, J. D.; Silva, C. M.; Baptista, F. I.; Alves, R. L.; Coelho-Santos, V.; Silva, A. P.; Paes-de-Carvalho, R.; Magalhaes, A.; Summavielle, T.; Brakebusch, C.; Sebastiao, A. M.; Ambrosio, A. F.; Relvas, J. B.
10.1101/218107 — neuroscience — Posted on 2020-06-02
4776 A membrane-depolarising toxin substrate of the Staphylococcus aureus Type VII secretion system mediates intra-species competition
Ulhuq, F. R.; Gomes, M. C.; Duggan, G.; Guo, M.; Mendonca, C.; Buchanan, G.; Chalmers, J. D.; Cao, Z.; Kneuper, H.; Murdoch, S.; Thomson, S.; Strahl, H.; Trost, M.; Mostowy, S.; Palmer, T.
10.1101/443630 — microbiology — Posted on 2020-06-02
4777 Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer
Selvanesan, B. C.; Chandra, D.; Quispe-Tintaya, W.; Jahangir, A.; Patel, A.; Meena, K.; Alberto Alves Da Silva, R.; Li, J.; Siddiqui, S.; Libutti, S. K.; Yuan, Z.; Beck, A.; Tesfa, L.; Koba, W.; Chuy, J.; McAuliffe, J. C.; Jafari, R.; Entenberg, D.; Wang, Y.; Condeelis, J.; Gravekamp, C.
10.1101/600106 — immunology — Posted on 2020-06-02
4778 Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Soliai, M.; Kato, A.; Stanhope, C. T.; Norton, J. E.; Naughton, K. A.; Klinger, A. I.; Kern, R. C.; Tan, B. K.; Schleimer, R. P.; Nicolae, D. L.; Pinto, J. M.; Ober, C.
10.1101/593558 — genomics — Posted on 2020-06-02
4779 Cryptic patterns of speciation in cryptic primates: microendemic mouse lemurs and the multispecies coalescent
Poelstra, J.; Salmona, J.; Tiley, G. P.; Schussler, D.; Blanco, M. B.; Andriambeloson, J. B.; Manzi, S.; Campbell, C. R.; Bouchez, O.; Etter, P. D.; Iribar, A.; Hohenlohe, P. A.; Hunnicutt, K. E.; Johnson, E. A.; Kappeler, P. M.; Larsen, P. A.; Ralison, J. M.; Randrianambinina, B.; Rasoloarison, R. M.; Rasolofoson, D. W.; Stahlke, A. R.; Weisrock, D.; Williams, R. C.; Chikhi, L.; Louis, E. E.; Radespiel, U.; Yoder, A. D.
10.1101/742361 — evolutionary biology — Posted on 2020-06-02
4787 Robotic Assay for Drought (RoAD): An Automated Phenotyping System for Brassinosteroid and Drought Response
Xiang, L.; Nolan, T. M.; Bao, Y.; Elmore, M.; Tuel, T.; Gai, J.; Shah, D.; Huser, N. M.; Hurd, A. M.; McLaughlin, S. A.; Howell, S. H.; Walley, J. W.; Yin, Y.; Tang, L.
10.1101/2020.06.01.128199 — plant biology — Posted on 2020-06-02
4789 Temperature restriction in entomopathogenic bacteria
Hapeshi, A.; Healey, J. R. J.; Mulley, G.; Waterfield, N. R.
10.1101/2020.06.02.129163 — microbiology — Posted on 2020-06-02
4790 Adaptive evolution of phenotypic switching during environmental change
Trivedi, U.; Rebsdorf, M. R.; Cueva, A. R.; Rumbaugh, K. P.; Burmolle, M.; Sorensen, S. J.; Madsen, J. S.
10.1101/2020.06.02.127241 — evolutionary biology — Posted on 2020-06-02
4793 A human TSC1 mutation screening platform in GABAergic cortical interneurons for Genotype to Phenotype assessments
Wundrach, D.; Martinetti, L. E.; Stafford, A. M.; Bilinovich, S. M.; Angara, K.; Crandall, S. R.; Vogt, D.
10.1101/2020.06.01.128611 — neuroscience — Posted on 2020-06-02
4796 Magnetosomes could be protective shields againstmetal stress in magnetotactic bacteria
Muñoz, D.; Marcano, L.; Martín-Rodríguez, R.; Simonelli, L.; Serrano, A.; García-Prieto, A.; Fdez-Gubieda, M. L.; Muela, A.
10.1101/2020.06.02.128942 — microbiology — Posted on 2020-06-02
4797 Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models
Li, W.; Drelich, A.; Martinez, D. R.; Gralinski, L. E.; Chen, C.; Sun, Z.; Schäfer, A.; Leist, S. R.; Liu, X.; Zhelev, D. V.; Zhang, L.; Peterson, E. L.; Conard, A.; Mellors, J. W.; Tseng, C.-T.; Baric, R. S.; Dimitrov, D. S.
10.1101/2020.05.13.093088 — microbiology — Posted on 2020-06-02
4802 Motor Protein MYO1C is Critical for Photoreceptor Opsin Trafficking and Vision
Solanki, A.; Obert, E.; Walterhouse, S.; Arif, E.; Lipschutz, J. H.; Sundstrom, J.; Rohrer, B.; Husain, S.; Lobo, G. P.; Nihalani, D.
10.1101/2020.06.02.129890 — cell biology — Posted on 2020-06-02
4805 In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19
Phan, I. Q.; Subramanian, S.; Kim, D.; Carter, L.; King, N.; Anishchenko, I.; Barrett, L. K.; Craig, J. K.; Tillery, L.; Shek, R.; Harrington, W. E.; Koelle, D. M.; Wald, A.; Boonyaratanakornkit, J.; Isoherranen, N.; Greninger, A. L.; Jerome, K. R.; Chu, H.; Staker, B.; Myler, P. J.; Van Voorhis, W. C.
10.1101/2020.05.22.111526 — bioinformatics — Posted on 2020-06-02
4813 A domestic cat whole exome sequencing resource for trait discovery
Rodney, A.; Buckley, R. M.; Fulton, R. S.; Fronick, C.; Richmond, T.; Helps, C. R.; Pantke, P.; Trent, D. J.; Lyons, L. A.; Warren, W. C.
10.1101/2020.06.01.128405 — bioinformatics — Posted on 2020-06-02
4814 Foxa1/2 downregulates liver differentiation markers and the endoderm and liver gene regulatory network in human stem cells and in a human stable liver cell line
Warren, I. T.; Maloy, M. H.; Guiggey, D.; Ogoke, O.; Groth, T. S.; Mon, T.; Meamardoost, S.; Liu, X.; Szeglowski, A.; Thompson, R.; Chen, P.; Paulmurugan, R.; Parashurama, N.
10.1101/2020.06.01.128108 — bioengineering — Posted on 2020-06-02
4817 Muscle fiber type differences in nitrate and nitrite storage and nitric oxide signaling in rats
Long, G. M.; Gray, D. A.; Troutman, A. D.; Fisher, A. J.; Brown, M. B.; Coggan, A. R.
10.1101/2020.06.01.128322 — physiology — Posted on 2020-06-02
4818 Moonstruck sleep: Synchronization of Human Sleep with the Moon Cycle under Natural Conditions
Casiraghi, L. P.; Spiousas, I.; Dunster, G.; McGlothlen, K.; Fernandez-Duque, E.; Valeggia, C.; de la Iglesia, H.
10.1101/2020.06.01.128728 — neuroscience — Posted on 2020-06-02
4820 Partitiviruses infecting Drosophila melanogaster and Aedes aegypti exhibit efficient biparental vertical transmission
Cross, S. T.; Maertens, B. L.; Dunham, T. J.; Rodgers, C. P.; Brehm, A. L.; Miller, M. R.; Williams, A. M.; Foy, B. D.; Stenglein, M. D.
10.1101/2020.06.01.128819 — microbiology — Posted on 2020-06-02
4822 Xrn1 influences RNA pol II-dependent transcription elongation rates across the yeast genome and this control is particularly relevant for late elongation of regulatory genes
Begley, V.; Jordan-Pla, A.; Penate, X.; Garrido-Godino, A. I.; Challal, D.; Cuevas-Bermudez, A.; Mitjavila, A.; Barucco, M.; Gutierrez, G.; Singh, A.; Alepuz, P.; Navarro, F.; Libri, D.; Perez-Ortin, J. E.; Chavez, S.
10.1101/2020.06.02.129171 — genomics — Posted on 2020-06-02
4825 The Guaymas Basin Subseafloor Sedimentary Archaeome Reflects Complex Environmental Histories
Ramirez, G. A.; McKay, L.; Fields, M.; Buckley, A.; Mortera, C.; Hensen, C.; Ravelo, A. C.; Teske, A.
10.1101/2020.06.01.109066 — ecology — Posted on 2020-06-02
4826 Morphological colour adaptation during development: Involvement of Growth Hormone Receptor 1
Delgadin, T. H.; Castaneda-Cortes, D. C.; Sacks, C.; Breccia, A.; Fernandino, J. I.; Vissio, P. G.
10.1101/2020.06.01.128538 — developmental biology — Posted on 2020-06-02
4827 Identification of polyketide biosynthetic gene clusters that harbor self-resistance target genes
Vandova, G. A.; Nivina, A.; Davis, R. W.; Khosla, C.; Fischer, C. R.; Hillenmeyer, M. E.
10.1101/2020.06.01.128595 — bioinformatics — Posted on 2020-06-02
4828 Detection of Chemotherapy-Resistant Pancreatic Cancer Using a Glycan Biomarker
Gao, C.; Wisniewski, L.; Liu, Y.; Staal, B.; Beddows, I.; Plenker, D.; Aldakkak, M.; Hall, J.; Barnett, D.; Kheir Gouda, M.; Allen, P.; Drake, R.; Zureikat, A.; Huang, Y.; Evans, D.; Singhi, A.; Brand, R. E.; Tuveson, D. A.; Tsai, S.; Haab, B.
10.1101/2020.06.01.128082 — cancer biology — Posted on 2020-06-02
4833 Shared SARS-CoV-2 diversity suggests localised transmission of minority variants
Lythgoe, K. A.; Hall, M. D.; Ferretti, L.; de Cesare, M.; MacIntyre-Cockett, G.; Trebes, A.; Andersson, M.; Otecko, N.; Wise, E. L.; Moore, N.; Lynch, J.; Kidd, S.; Cortes, N.; Mori, M.; Justice, A.; Green, A.; Ansari, M. A.; Abeler-Dorner, L.; Moore, C. E.; Peto, T. E. A.; Shaw, R.; Simmonds, P.; Buck, D.; Todd, J. A.; Bonsall, D.; Fraser, C.; Golubchik, T.
10.1101/2020.05.28.118992 — genomics — Posted on 2020-06-02
4835 Leveraging non-structural data to predict structures of protein-ligand complexes
Paggi, J. M.; Belk, J. A.; Hollingsworth, S. A.; Villanueva, N.; Powers, A. S.; Clark, M. J.; Chemparathy, A. G.; Tynan, J. E.; Lau, T. K.; Sunahara, R. K.; Dror, R. O.
10.1101/2020.06.01.128181 — biophysics — Posted on 2020-06-02
4836 Inhibition of Angiotensin II Dependent AT1a Receptor Stimulation Attenuates Thoracic Aortic Pathology in Fibrillin-1C1041G/+ Mice
Chen, J. Z.; Sawada, H.; Moorleghen, J. J.; Franklin, M. K.; Howatt, D. A.; Sheppard, M. B.; Mullick, A. E.; Lu, H. S.; Daugherty, A.
10.1101/2020.06.01.127670 — physiology — Posted on 2020-06-02
4838 Multifactorial and closed head impact traumatic brain injuries cause distinct tactile hypersensitivity profiles
Wattiez, A.-S.; Castonguay, W. C.; Gaul, O. J.; Waite, J. S.; Schmidt, C. M.; Reis, A. S.; Rea, B. J.; Sowers, L. P.; Cintron-Perez, C. J.; Vazquez-Rosa, E.; Pieper, A. A.; Russo, A. F.
10.1101/2020.06.01.127944 — neuroscience — Posted on 2020-06-02
4840 Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs
Aztekin, C.; Hiscock, T.; Gurdon, J.; Jullien, J.; Marioni, J.; Simons, B. D.
10.1101/2020.06.01.127654 — developmental biology — Posted on 2020-06-02
4843 Human es-fMRI Resource: Concurrent deep-brain stimulation and whole-brain functional MRI
Thompson, W.; Nair, R.; Oya, H.; Esteban, O.; Shine, J.; Petkov, C.; Poldrack, R.; Howard, M.; Adolphs, R.
10.1101/2020.05.18.102657 — neuroscience — Posted on 2020-06-02
4844 The neural representation of force across grasp types in motor cortex of humans with tetraplegia
Rastogi, A.; Willett, F. R.; Abreu, J.; Crowder, D. C.; Murphy, B.; Memberg, W. D.; Vargas-Irwin, C. E.; Miller, J. P.; Sweet, J.; Walter, B. L.; Rezaii, P. G.; Stavisky, S. D.; Hochberg, L. R.; Shenoy, K. V.; Henderson, J. M.; Kirsch, R. F.; Ajiboye, A. B.
10.1101/2020.06.01.126755 — neuroscience — Posted on 2020-06-02
4846 Genome-wide analysis in Escherichia coli unravels an unprecedented level of genetic homoplasy associated with cefotaxime resistance.
Coolen, J. P. M.; den Drijver, E.; Verweij, J. J.; Schildkraut, J.; Neveling, K.; Melchers, W. J. G.; Kolwijck, E.; Wertheim, H. F. L.; Kluytmans, J.; Huynen, M. A.
10.1101/2020.06.01.128843 — microbiology — Posted on 2020-06-02
4847 Evolution of Wolbachia Mutualism and Reproductive Parasitism: Insight from Two Novel Strains that Co-infect Cat Fleas
Driscoll, T.; Verhoeve, V. I.; Brockway, C.; Shrewsberry, D.; Plumer, M. L.; Sevdalis, S. E.; Beckmann, J. F.; Krueger Prelesnik, L. M.; Macaluso, K. R.; Azad, A. F.; Gillespie, J. J.
10.1101/2020.06.01.128066 — genomics — Posted on 2020-06-02
4850 Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14
Benoit, M. P. M. H.; Asenjo, A. B.; Paydar, M.; Dhakal, S.; Kwok, B. H.; Sosa, H.
10.1101/2020.06.01.128371 — cell biology — Posted on 2020-06-02
4851 Optimised assembly of DNA-lipid nanostructures
Darley, E.; Ridone, P.; Singh, J. K. D.; Wickham, S. F.; Baker, M. A.
10.1101/2020.06.01.128686 — biophysics — Posted on 2020-06-02
4852 Promiscuous esterases counterintuitively are less flexible than specific ones
Nutschel, C.; Mulnaes, D.; Coscolin, C.; Ferrer, M.; Jaeger, K.-E.; Gohlke, H.
10.1101/2020.06.02.129015 — biophysics — Posted on 2020-06-02
4854 Characterization of small molecule induced changes in Parkinson's-related trafficking via the Nedd4 ubiquitin signaling cascade
Hatstat, A. K.; Ahrendt, H. D.; Foster, M. W.; Mayne, L.; Moseley, M. A.; Englander, S. W.; McCafferty, D. G.
10.1101/2020.06.01.128348 — biochemistry — Posted on 2020-06-02
4856 Structure of the human heterotetrameric cis-prenyltransferase complex
Lisnyansky Bar-El, M.; Vankova, P.; Man, P.; Haitin, Y.; Giladi, M.
10.1101/2020.06.02.095570 — biochemistry — Posted on 2020-06-02
4857 Structural Brain Imaging Studies Offer Clues about the Effects of the Shared Genetic Etiology among Neuropsychiatric Disorders
Radonjic, N. V.; Hess, J. L.; Rovira, P.; Andreassen, O.; Buitelaar, J. K.; Ching, C. R. K.; Franke, B.; Hoogman, M.; Jahanshad, N.; McDonald, C.; Schmaal, L.; Sisodiya, S. M.; Stein, D. J.; van den Heuvel, O. A.; van Erp, T. G. M.; van Rooij, D.; Veltman, D. J.; Thompson, P.; Faraone, S. V.
10.1101/809582 — neuroscience — Posted on 2020-06-02
4860 CytofRUV: Removing unwanted variation to integrate multiple CyTOF datasets
Trussart, M.; Teh, C. E.; Tan, T.; Leong, L.; Gray, D. H.; Speed, T. P.
10.1101/2020.05.09.085621 — bioinformatics — Posted on 2020-06-02
4864 HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes
Marshall, J. L.; Doughty, B. R.; Subramanian, V.; Wang, Q.; Chen, L. M.; Rodriques, S. G.; Zhang, K.; Guckelberger, P.; Fulco, C. P.; Nasser, J.; Grinkevich, E. J.; Noel, T.; Mangiameli, S.; Greka, A.; Lander, E. S.; Chen, F.; Engreitz, J. M.
10.1101/2020.06.01.128314 — genomics — Posted on 2020-06-02
4865 Systematic characterization of somatic mutation-mediated microRNA regulatory network perturbations
Hua, X.; Li, Y.; Guo, L.; Xu, M.; Qi, D.; Huang, J. H.; Bhat, A.; Zhou, Y.; Wu, E.; Yi, S. S.
10.1101/2020.06.02.128777 — bioinformatics — Posted on 2020-06-02
4866 The onset and prevalence of motor and psychiatric symptoms in Huntingtons disease
McAllister, B.; Gusella, J. F.; Landwehrmeyer, G. B.; Lee, J.-M.; MacDonald, M. E.; Orth, M.; Rosser, A. E.; Williams, N. M.; REGISTRY Investigators of the European Huntingtons disease network, ; Holmans, P.; Jones, L.; Massey, T. H.
10.1101/2020.05.26.116798 — neuroscience — Posted on 2020-06-02
4868 Novel ionic liquids-based extraction method that preserves molecular structure from cutin
Moreira, C. J.; Bento, A.; Pais, J.; Petit, J.; Escorcio, R.; Correia, V.; Pinheiro, A.; Halinski, Łukasz P.; Mykhaylyk, O. O.; Rothan, C.; Silva Pereira, C.
10.1101/2020.06.01.127837 — plant biology — Posted on 2020-06-02
4869 Autophagy in T cells from aged donors is maintained by spermidine, and correlates with function and vaccine responses
Alsaleh, G.; Panse, I.; Swadling, L.; Zhang, H.; Meyer, A.; Lord, J.; Barnes, E.; Klenerman, P.; Green, C.; Simon, K.
10.1101/2020.06.01.127514 — physiology — Posted on 2020-06-02
4871 Lineage and Spatial Mapping of Glioblastoma-associated Immunity
Ravi, V. M.; Neidert, N.; Will, P.; Joseph, K.; Kuekelhaus, J.; Vollmer, L.; Goeldner, J.; Behringer, S.; Scherer, F.; Boerries, M.; Follo, M.; Weiss, T.; Delev, D.; Kernbach, J.; Franco, P.; Schallner, N.; Scheiwe, C.; Carro, M. S.; Hofmann, U. G.; Fung, C.; Beck, J.; Sankowski, R.; Prinz, M.; Schnell, O.; Heiland, D. H.
10.1101/2020.06.01.121467 — cancer biology — Posted on 2020-06-02
4872 Exploring the Stony Coral Tissue Loss Disease Bacterial Pathobiome
Iwanowicz, D. D.; Schill, W. B.; Woodley, C. M.; Bruckner, A.; Neely, K.; Briggs, K. M.
10.1101/2020.05.27.120469 — microbiology — Posted on 2020-06-02
4875 High titer methyl ketone production with tailored Pseudomonas taiwanensis VLB120
Nies, S. C.; Alter, T. B.; Noelting, S.; Thiery, S.; Phan, A. N. T.; Drummen, N.; Keasling, J. D.; Blank, L. M.; Ebert, B. E.
10.1101/2020.06.02.125906 — synthetic biology — Posted on 2020-06-02
4876 Feeding dihydroquercetin and vitamin E to broiler chickens reared at standard and high ambient temperatures
Pirgozliev, V.; Westbrook, C.; Woods, S.; Mansbridge, S. C.; Rose, P.; Whiting, I.; Yovchev, D.; Atanasov, A.; Kljak, K.; Staykova, G.; Ivanova, S.; Karagecili, M. R.; Karadas, F.; Stringhini, J. H.
10.1101/2020.05.19.104398 — physiology — Posted on 2020-06-02
4880 Analysis of ongoing neuronal activity evoked by continuous speech with computational corpus linguistics methods
Schilling, A.; Tomasello, R.; Henningsen-Schomers, M. R.; Surendra, K.; Haller, M.; Karl, V.; Uhrig, P.; Maier, A.; Krauss, P.
10.1101/2020.04.21.052720 — neuroscience — Posted on 2020-06-02
4881 Risk-based Decision Making in Rats: Modulation by Sex and Amphetamine
Islas-Preciado, D.; Wainwright, S. R.; Sniegocki, J.; Lieblich, S. E.; Yagi, S.; Floresco, S. B.; Galea, L. A. M.
10.1101/2020.03.09.981563 — neuroscience — Posted on 2020-06-02
4882 Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons
Schwartzentruber, A.; Boschian, C.; Lopes, F. M.; Myszczynska, M. A.; New, E. J.; Beyrath, J.; Smeitink, J.; Ferraiuolo, L.; Mortiboys, H.
10.1101/2020.05.29.115782 — neuroscience — Posted on 2020-06-02
4886 Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area
Nagaeva, E.; Zubarev, I.; Gonzales, C. B.; Forss, M.; Nikouei, K.; de Miguel, E.; Elsilä, L.; Linden, A.-M.; Hjerling-Leffler, J.; Augustine, G. J.; Korpi, E. R.
10.1101/2020.05.28.120592 — neuroscience — Posted on 2020-06-02
4887 DNA Methylation Biomarkers Of Myocardial Infarction And Cardiovascular Disease
Fernandez-Sanles, A.; Sayols-Baixeras, S.; Subirana, I.; Senti, M.; Perez-Fernandez, S.; Castro de Moura, M.; Esteller, M.; Marrugat, J.; Elosua, R.
10.1101/707315 — genomics — Posted on 2020-06-02
4890 Prospects and limitations of expansion microscopy in chromatin ultrastructure determination
Kubalova, I.; Schmidt Cernohorska, M.; Huranova, M.; Weisshart, K.; Houben, A.; Schubert, V.
10.1101/2020.03.16.994186 — cell biology — Posted on 2020-06-02
4891 Towards a consensus microRNA signature of primary and metastatic colorectal cancer
Fromm, B.; Hoye, E.; Bottger, P. H. M.; Domanska, D.; Kristensen, A. T.; Lund-Andersen, C.; Abrahamsen, T. W.; Fretland, A. A.; Dagenborg, V. J.; Lorenz, S.; Edwin, B.; Hovig, E.; Flatmark, K.
10.1101/2020.06.01.127647 — cancer biology — Posted on 2020-06-02
4895 Brain Tumor IDH, 1p/19q, and MGMT Molecular Classification Using MRI-based Deep Learning: Effect of Motion and Motion Correction
Nalawade, S.; Yu, F. F.; Bangalore Yogananda, C. G.; Murugesan, G. K.; Shah, B. R.; Pinho, M. C.; Wagner, B. C.; Mickey, B.; Patel, T. R.; Fei, B.; Madhuranthakam, A. J.; Maldjian, J. A.
10.1101/2020.06.01.126375 — neuroscience — Posted on 2020-06-02
4896 The mechanism of analgesia in Nav1.7 null mutants
macdonald, d.; sikandar, s.; weiss, j.; pyrski, m.; luiz, a.; millet, q.; emery, e.; mancini, f.; Iannetti, G. D.; alles, s.; zhao, j.; cox, j.; brownstone, R.; Zufall, f.; wood, j.
10.1101/2020.06.01.127183 — neuroscience — Posted on 2020-06-02
4899 Global impacts of climate change on avian functional diversity
Stewart, P. S.; Voskamp, A.; Biber, M. F.; Hof, C.; Willis, S. G.; Tobias, J. A.
10.1101/2020.06.01.127779 — ecology — Posted on 2020-06-02
4902 Tension promotes kinetochore-microtubule release in response to Aurora B activity
Chen, G.-Y.; Renda, F.; Zhang, H.; Gokden, A.; Wu, D. Z.; Chenoweth, D. M.; Khodjakov, A.; Lampson, M.
10.1101/2020.06.01.127795 — cell biology — Posted on 2020-06-02
4903 Towards a consensus microRNA signature of primary and metastatic colorectal cancer
Hoye, E.; Fromm, B.; Bottger, P. H. M.; Domanska, D.; Kristensen, A. T.; Lund-Andersen, C.; Abrahamsen, T. W.; Fretland, A. A.; Dagenborg, V. J.; Lorenz, S.; Edwin, B.; Hovig, E.; Flatmark, K.
10.1101/2020.06.01.127647 — cancer biology — Posted on 2020-06-02
4905 Haplotype-Resolved Assembly for Synthetic Long Reads Using a Trio-Binning Strategy
Xu, M.; Guo, L.; Du, X.; Li, L.; Deng, L.; Wang, O.; Ni, M.; Yang, H.; Xu, X.; Liu, X.; Huang, J.; Fan, G.
10.1101/2020.06.01.126995 — bioinformatics — Posted on 2020-06-02
4906 High-density, targeted monitoring of tyrosine phosphorylation reveals activated signaling networks in human tumors
Stopfer, L. E.; Flower, C. T.; Gajadhar, A. S.; Patel, B.; Gallien, S.; Lopez-Ferrer, D.; White, F.
10.1101/2020.06.01.127787 — bioengineering — Posted on 2020-06-02
4907 Effectiveness of Growth Hormone Releasing Hormone Agonists (GHRH A) in Chronic Kidney Disease Induced Heart Failure with Preserved Ejection Fraction
Rieger, A. C.; Bagno, L. L.; Salerno, A.; Florea, V.; Rodriguez, J.; Rosado, M.; Turner, D.; Takeuchi, L. M.; Dulce, R. A.; Balkan, W.; Schulman, I. H.; Schally, A.; Hare, J. M.
10.1101/2020.05.30.111476 — physiology — Posted on 2020-06-02
4908 Patterns of multisensory facilitation distinguish peripersonal from reaching space
Zanini, A.; Patane, I.; Blini, E.; Salemme, R.; Koun, E.; Farne, A.; Brozzoli, C.
10.1101/2020.06.01.127282 — neuroscience — Posted on 2020-06-02
4910 Phenome-wide investigation of the causal associations between childhood BMI and adult outcomes: A two-sample Mendelian randomization study
Dong, S.-S.; Zhang, K.; Guo, Y.; Ding, J.-M.; Feng, J.-C.; Yao, S.; Hao, R.-H.; Rong, Y.; Jiang, F.; Chen, J.-B.; Wu, H.; Chen, X.-F.; Yang, T.-L.
10.1101/2020.06.01.127530 — genetics — Posted on 2020-06-02
4911 Neonatal hyperoxia inhibits proliferation of atrial cardiomyocytes by suppressing fatty acid synthesis
Cohen, E. D.; Yee, M.; Porter, G. A.; McDavid, A.; Brookes, P. S.; Pryhuber, G. S.; O'Reilly, M. A.
10.1101/2020.06.01.127621 — developmental biology — Posted on 2020-06-02
4914 Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis
Ianevski, A.; Kulesskiy, E.; Krpina, K.; Lou, G.; Aman, Y.; Bugai, A.; Aasumets, K.; Akimov, Y.; Bulanova, D.; Gildemann, K.; Arutyunyan, A. F.; Susova, O. Y.; Zhuze, A. L.; Ji, P.; Wang, W.; Holien, T.; Bugge, M.; Zusinaite, E.; Oksenych, V.; Lysvand, H.; Gerhold, J.; Bjoras, M.; Waage, A.; Johansen, P.; Heckman, C.; Fang, E. F.; Kainov, D. E.
10.1101/2020.01.13.904714 — cancer biology — Posted on 2020-06-02
4916 Efficient variance components analysis across millions of genomes
Pazokitoroudi, A.; Wu, Y.; S. Burch, K.; Hou, K.; Pasaniuc, B.; Sankararaman, S.
10.1101/522003 — bioinformatics — Posted on 2020-06-02
4921 Pharmacogenetics at scale: An analysis of the UK Biobank
McInnes, G. M.; Lavertu, A.; Sangkuhl, K.; Klein, T. E.; Whirl-Carrillo, M.; Altman, R. B.
10.1101/2020.05.30.125583 — genomics — Posted on 2020-06-02
4922 Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene
Akerman, I.; Maestro, M. A.; Grau, V.; Mittler, G.; Garcia Hurtado, J.; Ravassard, P.; Piemonti, L.; Ferrer, J.
10.1101/2020.05.31.125377 — genomics — Posted on 2020-06-02
4923 Identifying rare, medically-relevant genetic variation in a diverse population: opportunities and pitfalls
Bowling, K. M.; Thompson, M. L.; Gray, D. E.; Lawlor, J. M.; Williams, K.; East, K. M.; Kelley, W. V.; Moss, I. P.; Absher, D. M.; Partridge, E. C.; Hurst, A. C.; Edberg, J. C.; Barsh, G. S.; Korf, B. R.; Cooper, G. M.
10.1101/2020.05.28.122457 — genetics — Posted on 2020-06-02
4924 Vector genetics, insecticide resistance and gene drives: an agent-based modeling approach to evaluate malaria transmission and elimination
Selvaraj, P.; Wenger, E. A.; Bridenbecker, D.; Windbichler, N.; Russell, J. R.; Gerardin, J.; Bever, C. A.; Nikolov, M.
10.1101/2020.01.27.920421 — genetics — Posted on 2020-06-02
4925 Population structure of the invasive golden mussel (Limnoperna fortunei) on reservoirs from five Brazilian drainage basins
Rodinho Nunes Ferreira, J. G.; Soares Souza, G. B.; Americo, J. A.; Silva Romao Dumaresq, A.; de Freitas Rebelo, M.
10.1101/2020.05.28.122069 — genetics — Posted on 2020-06-02
4931 Multi-channel intraneural vagus nerve recordings with a novel high-density carbon fiber microelectrode array
Jiman, A. A.; Ratze, D. C.; Welle, E. J.; Patel, P. R.; Richie, J. M.; Bottorff, E. C.; Seymour, J. P.; Chestek, C. A.; Bruns, T. M.
10.1101/2020.05.15.098301 — bioengineering — Posted on 2020-06-01
4935 Extensive and diverse patterns of cell death sculpt neural networks in insects.
Pop, S.; Chen, C.-L.; Sproston, C. J.; Kondo, S.; Ramdya, P.; Williams, D. W.
10.1101/626465 — neuroscience — Posted on 2020-06-01
4938 An approach for normalization and quality control for NanoString RNA expression data
Bhattacharya, A.; Hamilton, A. M.; Furberg, H.; Pietzak, E.; Purdue, M. P.; Troester, M. A.; Hoadley, K. A.; Love, M. I.
10.1101/2020.04.08.032490 — genomics — Posted on 2020-06-01
4939 Stutter: a Transient Dynamic Instability Phase that is Strongly Associated with Catastrophe
Mahserejian, S. M.; Scripture, J. P.; Mauro, A. J.; Lawrence, E. J.; Jonasson, E. M.; Murray, K. S.; Li, J.; Gardner, M. K.; Alber, M.; Zanic, M.; Goodson, H. V.
10.1101/2019.12.16.878603 — cell biology — Posted on 2020-06-01
4941 Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction
Lee-Montiel, F. T.; Laemmle, A.; Dumont, L.; Lee, C. S.; Huebsch, N.; Charwat, V.; Okochi, H.; Hancock, M. J.; Siemons, B.; Boggess, S. C.; Goswami, I.; Miller, E.; Willenbring, H.; Healy, K.
10.1101/2020.05.24.112771 — bioengineering — Posted on 2020-06-01
4947 Shaky Scaffolding: Age Differences In Cerebellar Activation Revealed Through Activation Likelihood Estimation Meta-Analysis
Bernard, J.; Nguyen, A. D.; Hausman, H. K.; Maldonado, T.; Ballard, H. K.; Jackson, T. B.; Eakin, S. M.; Lokshina, Y.; Goen, J. R. M.
10.1101/716530 — neuroscience — Posted on 2020-06-01
4949 Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Soliai, M.; Kato, A.; Stanhope, C. T.; Norton, J. E.; Naughton, K. A.; Klinger, A. I.; Kern, R. C.; Tan, B. K.; Schleimer, R. P.; Nicolae, D. L.; Pinto, J. M.; Ober, C.
10.1101/593558 — genomics — Posted on 2020-06-01
4951 The 20S proteasome activator PA28γ controls the compaction of chromatin
Fesquet, D.; Lleres, D.; Grimaud, C.; Vigano, C.; Mechali, F.; Boulon, S.; Feil, R.; Coux, O.; Bonne-Andrea, C.; Baldin, V.
10.1101/716332 — cell biology — Posted on 2020-06-01
4953 A Modular Framework for Multiscale Spatial Modeling of Viral Infection and Immune Response in Epithelial Tissue
Sego, T. J.; Aponte-Serrano, J. O.; Ferrari Gianlupi, J.; Heaps, S.; Breithaupt, K.; Brusch, L.; Osborne, J. M.; Quardokus, E. M.; Plemper, R. K.; Glazier, J. A.
10.1101/2020.04.27.064139 — bioengineering — Posted on 2020-06-01
4956 The Genomic Loci of Specific Human tRNA Genes Exhibit Ageing-Related DNA Hypermethylation
Acton, R. J.; Yuan, W.; Gao, F.; Xia, Y.; Bourne, E.; Wozniak, E.; Bell, J.; Lillycrop, K.; Wang, J.; Dennison, E.; Harvey, N.; Mein, C. A.; Spector, T. D.; Hysi, P. G.; Cooper, C.; Bell, C. G.
10.1101/870352 — genomics — Posted on 2020-06-01
4957 The gene cortex controls scale colour identity in Heliconius
Livraghi, L.; Hanly, J. J.; Loh, L. S.; Ren, A.; Warren, I. A.; Concha, C.; Wright, C.; Walker, J. M.; Foley, J.; Arenas-Castro, H.; Brenes, L. R.; Martin, A.; McMillan, W. O.; Jiggins, C. D.
10.1101/2020.05.26.116533 — evolutionary biology — Posted on 2020-06-01
4959 SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
Bojkova, D.; Wagner, J.; Shumliakivska, M.; Aslan, G.; Saleem, U.; Hansen, A.; Luxan, G.; Guenther, S.; Pham, M. D.; Krishnan, J.; Harter, P.; Ermel, U.; Frangakis, A. S.; Zeiher, A.; Milting, H.; Cinatl, J.; Dendorfer, A.; Eschenhagen, T.; Ciesek, S.; Dimmeler, S.
10.1101/2020.06.01.127605 — cell biology — Posted on 2020-06-01
4963 A neural system that represents the association of odors with rewarded outcomes and promotes behavioral engagement
Gadziola, M. A.; Stetzik, L. A.; Wright, K. N.; Milton, A. J.; Arakawa, K.; del Mar Cortijo, M.; Wesson, D. W.
10.1101/617902 — neuroscience — Posted on 2020-06-01
4965 Spliced peptides and cytokine driven changes in the immunopeptidome of melanoma
Faridi, P.; Woods, K.; Ostrouska, S.; Deceneux, C.; Wong, S. Q.; Chen, W.; Aranha, R.; Duscharla, D.; Croft, N. P.; Li, C.; Ayala, R.; Cebon, J.; Purcell, A. W.; Schittenhelm, R. B.; Behren, A.
10.1101/623223 — immunology — Posted on 2020-06-01
4966 Evidence of natural selection in human complex phenotypes from GWAS summary statistics
Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.
10.1101/705285 — genomics — Posted on 2020-06-01
4967 Extensive genetic diversity in Plasmodium vivax from Sudan and its genetic relationships with other geographical isolates
Albsheer, M. M. A.; Gebremeskel, E. I.; Kepple, D.; Lo, E.; Rougeron, V.; Ibrahim, M. E.; Mahdi Abdel Hamid, M.
10.1101/2020.06.01.127423 — genetics — Posted on 2020-06-01
4968 The conserved Cdc14 phosphatase ensures effective resolution of meiotic recombination intermediates.
Alonso-Ramos, P.; Alvarez-Melo, D.; Strouhalova, K.; Pascual-Silva, C.; Garside, G. B.; Arter, M.; Bermejo, T.; Grigaitis, R.; Wettstein, R.; San-Segundo, P. A.; Matos, J.; Geymonat, M.; Carballo, J. A.
10.1101/571083 — genetics — Posted on 2020-06-01
4969 Different organic manure sources and NPK fertilizer on soil chemical properties, growth, yield and quality of okra
Adekiya, A.; Ejue, W. S.; Olayanju, A.; Dunsin, O.; Aboyeji, C. M.; Aremu, C.; Adegbite, K.; Akinpelu, O.
10.1101/2020.06.01.127498 — ecology — Posted on 2020-06-01
4975 Reconstructing SARS-CoV-2 response signaling and regulatory networks
Ding, J.; Lugo-Martinez, J.; Yuan, Y.; Kotton, D. N.; Bar-Joseph, Z.
10.1101/2020.06.01.127589 — systems biology — Posted on 2020-06-01
4976 Improved and Simplified Diagnosis of Covid-19 using TE Extraction from Dry Swabs
Kiran, U.; Gokulan, C. G.; Kuncha, S. K.; Vedagiri, D.; Tallapaka, K. B.; Mishra, R. K.; Harshan, K.
10.1101/2020.05.31.126342 — molecular biology — Posted on 2020-06-01
4979 Generation of human bronchial organoids for SARS-CoV-2 research
Suzuki, T.; Ito, Y.; Sakai, Y.; Saito, A.; Okuzaki, D.; Motooka, D.; Minami, S.; Kobayashi, T.; Yamamoto, T.; Okamoto, T.; Takayama, K.
10.1101/2020.05.25.115600 — cell biology — Posted on 2020-06-01
4980 Minimal system for assembly of SARS-CoV-2 virus like particles
Swann, H.; Sharma, A.; Preece, B.; Peterson, A.; Eldredge, C.; Belnap, D.; Vershinin, M.; Saffarian, S.
10.1101/2020.06.01.128058 — biophysics — Posted on 2020-06-01
4984 Ozone Treatment for Elimination of Bacteria and SARS-CoV-2 for Medical Environments
Westover, C.; Rahmatulloev, S.; Danko, D.; Afshinnekoo, E.; O'Hara, N. B.; Ounit, R.; Bezdan, D.; Mason, C. E.
10.1101/420737 — microbiology — Posted on 2020-06-01
4985 PEDF-Rpsa-Itga6 signaling regulates cortical neuronal morphogenesis
Blazejewski, S. M.; Bennison, S. A.; Ha, N. T.; Liu, X.; Smith, T. H.; Dougherty, K. J.; Toyo-oka, K.
10.1101/2020.01.06.895672 — neuroscience — Posted on 2020-06-01
4987 A physical mechanism of TANGO1-mediated bulky cargo export
Raote, I.; Chabanon, M.; Walani, N.; Arroyo, M.; Garcia-Parajo, M. F.; Malhotra, V.; Campelo, F.
10.1101/576637 — biophysics — Posted on 2020-06-01
4988 The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase
Alhammad, Y. M. O.; Kashipathy, M. M.; Roy, A.; Gagne, J.-P.; Nonfoux, L.; McDonald, P.; Gao, P.; Battaile, K. P.; Johnson, D. K.; Poirier, G. G.; Lovell, S. W.; Fehr, A. R.
10.1101/2020.05.11.089375 — biochemistry — Posted on 2020-06-01
4994 Map making: Constructing, combining, and inferring on abstract cognitive maps
Park, S. A.; Miller, D. S.; Nili, H.; Ranganath, C.; Boorman, E. D.
10.1101/810051 — neuroscience — Posted on 2020-06-01
4996 Voltage-gated Ca2+ and K+ channel coupling regulates CA1 hippocampal synaptic filtering and spine excitability
Murphy, J. G.; Gutzmann, J. J.; Lin, L.; Hu, J.; Petralia, R. S.; Wang, Y.-X.; Hoffman, D. A.
10.1101/2020.05.27.119305 — neuroscience — Posted on 2020-06-01
4997 Lung Bronchial Epithelial Cells are HIV Targets for Proviral Genomic Integration
Devadoss, D.; Singh, S. P.; Acharya, A.; Do, K. C.; Periyasamy, P.; Manevski, M.; Mishra, N.; Tellez, C.; Ramakrishnan, S.; Belinsky, S.; Byrareddy, S.; Buch, S.; Chand, H. S.; Sopori, M.
10.1101/2020.06.01.126821 — physiology — Posted on 2020-06-01
4998 Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations
Hemez, C.; Clarelli, F.; Palmer, A. C.; Chindelevitch, L.; Cohen, T.; Abel zur Wiesch, P.
10.1101/2020.06.01.127571 — pharmacology and toxicology — Posted on 2020-06-01
5002 Neuronal activity remodels the F-actin based submembrane lattice in dendrites but not axons of hippocampal neurons
Lavoie-Cardinal, F.; Bilodeau, A.; Lemieux, M.; Gardner, M.-A.; Wiesner, T.; Laramee, G.; Gagne, C.; De Koninck, P.
10.1101/2020.05.27.119453 — neuroscience — Posted on 2020-06-01
5003 Characterisation of the Renal Cortical Transcriptome Following Roux-en-Y Gastric Bypass Surgery in Experimental Diabetic Kidney Disease.
Nair, M.; Martin, W. P.; Zhernovkov, V.; Fearon, N.; Elliott, J. A.; Eckhardt, H. G.; McCormack, J.; Godson, C.; Brennan, E. P.; Fandriks, L.; Docherty, N.; le Roux, C. W.
10.1101/2020.06.01.120980 — molecular biology — Posted on 2020-06-01
5005 Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge
Ryan, K. A.; Bewley, K. R.; Fotheringham, S. A.; Brown, P.; Hall, Y.; Marriott, A. C.; Tree, J. A.; Allen, L.; Aram, M. J.; Brunt, E.; Buttigieg, K. R.; Cavell, B. E.; Carter, D. P.; Cobb, R.; Coombes, N. S.; Godwin, K. J.; Gooch, K. E.; Gouriet, J.; Halkerston, R.; Harris, D. J.; Humphries, H. E.; Hunter, L.; Ho, C. M. K.; Kennard, C. L.; Leung, S.; Ngabo, D.; Osman, K. L.; Paterson, J.; Penn, E. J.; Pullan, S. T.; Rayner, E.; Slack, G. S.; Steeds, K.; Taylor, I.; Tipton, T.; Thomas, S.; Wand, N. I.; Watson, R. J.; Wiblin, N. R.; Charlton, S.; Hallis, B.; Hiscox, J. A.; Funnell, S.; Dennis, M
10.1101/2020.05.29.123810 — microbiology — Posted on 2020-06-01
5006 Ancient admixture into Africa from the ancestors of non-Africans
Cole, C. B.; Zhu, S. J.; Mathieson, I.; Prfüer, K.; Lunter, G.
10.1101/2020.06.01.127555 — genomics — Posted on 2020-06-01
5009 Cooperative action of miR-124 and ISX9 in instructing direct reprogramming of mouse astrocytes to induced-neurons in vitro and in vivo
Papadimitriou, E.; Koutsoudaki, P. N.; Karamitros, T.; Karagkouni, D.; Chroni-Tzartou, D.; Margariti, M.; Gkemisis, C.; Xingi, E.; Thanou, I.; Tzartos, S. J.; Hatzigeorgiou, A. G.; Thomaidou, D.
10.1101/2020.06.01.127126 — neuroscience — Posted on 2020-06-01
5011 Anipose: a toolkit for robust markerless 3D pose estimation
Karashchuk, P.; Rupp, K. L.; Dickinson, E. S.; Sanders, E.; Azim, E.; Brunton, B. W.; Tuthill, J. C.
10.1101/2020.05.26.117325 — neuroscience — Posted on 2020-06-01
5014 Giotto, a toolbox for integrative analysis and visualization of spatial expression data
Dries, R.; Zhu, Q.; Dong, R.; Eng, C.-H. L.; Li, H.; Liu, K.; Fu, Y.; Zhao, T.; Sarkar, A.; Bao, F.; George, R. E.; Pierson, N.; Cai, L.; Yuan, G.-C.
10.1101/701680 — bioinformatics — Posted on 2020-06-01
5015 Cytokinin-promoted secondary growth and nutrient storage in the perennial stem zone of Arabis alpina
Sergeeva, A.; Liu, H.; Mai, H.-J.; Mettler-Altmann, T.; Kiefer, C.; Coupland, G.; Bauer, P.
10.1101/2020.06.01.124362 — plant biology — Posted on 2020-06-01
5016 Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals
Vallone, F.; Ottaviani, M. M.; Dedola, F.; Cutrone, A.; Romeni, S.; Macri Panarese, A.; Bernini, F.; Cracchiolo, M.; Gabisonia, K.; Gorgodze, N.; Mazzoni, A.; Recchia, F. A.; Micera, S.
10.1101/2020.06.01.127050 — neuroscience — Posted on 2020-06-01
5017 A scale-space approach for 3D neuronal traces analysis
Phan, M.-S.; Matho, K. S.; Livet, J.; Beaurepaire, E.; Chessel, A.
10.1101/2020.06.01.127035 — neuroscience — Posted on 2020-06-01
5018 Deep sncRNA-seq of the PPMI cohort to study Parkinson's disease progression
Kern, F.; Fehlmann, T.; Violich, I.; Alsop, E.; Hutchins, E.; Kahraman, M.; Grammes, N. L.; Guimaraes, P.; Backes, C.; Poston, K.; Casey, B.; Balling, R.; Geffers, L.; Krueger, R.; Galasko, D.; Mollenhauer, B.; Meese, E.; Wyss-Coray, T.; Craig, D. W.; Van Keuren-Jensen, K.; Keller, A.
10.1101/2020.06.01.127092 — neuroscience — Posted on 2020-06-01
5019 Disruption of glycogen metabolism alters cell size in Escherichia coli
van der Walt, F. E.; Buergy, L.; Engelbrecht, L.; Adams, R. C.; de Stadler, J.; Strydom, L.; George, G. M.; Zeeman, S.; Kossmann, J.; Lloyd, J. R.
10.1101/2020.06.01.127233 — microbiology — Posted on 2020-06-01
5021 HAPPI GWAS: Holistic Analysis with Pre and Post Integration GWAS
Slaten, M. L.; Chan, Y. O.; Shrestha, V.; Lipka, A. E.; Angelovici, R.
10.1101/2020.04.07.998690 — bioinformatics — Posted on 2020-06-01
5023 An enormous Paris polyphylla genome sheds light on genome size evolution and polyphyllin biogenesis
Li, J.; Lv, M.; Du, L.; A, Y.; Hao, S.; Zhang, Y.; Zhang, X.; Guo, L.; Gao, X.; Deng, L.; Zhang, X.; Shi, C.; Guo, F.; Liu, R.; Fang, B.; Su, Q.; Hu, X.; Su, X.; Lin, L.; Liu, Q.; Wang, Y.; Qin, Y.; Zhang, W.; Li, S.; Liu, C.; Li, H.
10.1101/2020.06.01.126920 — plant biology — Posted on 2020-06-01
5027 Dense Computer Replica of Cortical Microcircuits Unravels Cellular Underpinnings of Auditory Surprise Response
Amsalem, O.; King, J.; Reimann, M. W.; Ramaswamy, S.; Muller, E.; Markram, H.; Nelken, I.; Segev, I.
10.1101/2020.05.31.126466 — neuroscience — Posted on 2020-06-01
5028 Low convergent validity of FLB 457
Freiburghaus, T.; Svensson, J. E.; Matheson, G. J.; Plaven-Sigray, P.; Lundberg, J.; Farde, L.; Cervenka, S.
10.1101/2020.06.01.127027 — neuroscience — Posted on 2020-06-01
5030 Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus
Zhang, Y.-H.; Xu, M.; Li, S.; Wu, H.; Shi, X.; Guo, X.; Mu, W.; Gong, L.; Yao, M.; He, M.; Wu, Q.-F.
10.1101/2020.06.01.125054 — developmental biology — Posted on 2020-06-01
5035 Language impairment with a microduplication in 1q42.3q43
Benitez-Burraco, A.; Fernandez-Urquiza, M.; Jimenez-Romero, M. S.
10.1101/2020.05.26.117903 — neuroscience — Posted on 2020-06-01
5036 Characterization of genomic variants associated with resistance to bedaquiline and delamanid in naïve Mycobacterium tuberculosis clinical strains
Battaglia, S.; Spitaleri, A.; Cabibbe, A.; Meehan, C.; Utpatel, C.; Ismail, N.; Tahseen, S.; Skrahina, A.; Alikhanova, N.; Mostofa, K. S.; Barbova, A.; Niemann, S.; Groenheit, R.; Dean, A.; Zignol, M.; Rigouts, L.; Cirillo, D.
10.1101/2020.05.27.120451 — microbiology — Posted on 2020-06-01
5037 Classification of the glyphosate target enzyme (5-enolpyruvylshikimate-3-phosphate synthase)
Leino, L.; Tall, T.; Helander, M.; Saloniemi, I.; Saikkonen, K.; Ruuskanen, S.; Puigbo, P.
10.1101/2020.05.27.118265 — bioinformatics — Posted on 2020-06-01
5038 A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus
Uchigashima, M.; Konno, K.; Demchak, E.; Cheung, A.; Watanabe, T.; Keener, D.; Abe, M.; Le, T.; Sakimura, K.; Sasaoka, T.; Uemura, T.; Kawasawa, Y. I.; Watanabe, M.; Futai, K.
10.1101/2020.05.27.119024 — neuroscience — Posted on 2020-06-01
5039 The binding mechanism of Streptococcus suis accessory virulence factor and adhesin SadP to globotetraosylceramide
Johansson, M. M.; Belurier, E.; Papageorgiou, A. C.; Sundin, A. P.; Rahkila, J.; Kallonen, T.; Nilsson, U. J.; Maatsola, S.; Nyholm, T. K. M.; Käpylä, J.; Corander, J.; Leino, R.; Finne, J.; Teneberg, S.; Haataja, S.
10.1101/2020.05.29.122762 — microbiology — Posted on 2020-06-01
5042 Pathogenesis, transmission and response to re-exposure of SARS-CoV-2 in domestic cats
Bosco-Lauth, A. M.; Hartwig, A. E.; Porter, S. M.; Gordy, P. W.; Nehring, M.; Byas, A. D.; VandeWoude, S.; Ragan, I. K.; Maison, R. M.; Bowen, R. A.
10.1101/2020.05.28.120998 — microbiology — Posted on 2020-06-01
5044 Quantifying multi-species microbial interactions in the larval zebrafish gut
Sundarraman, D.; Hay, E. A.; Martins, D. M.; Shields, D. S.; Pettinari, N. L.; Parthasarathy, R.
10.1101/2020.05.28.121855 — microbiology — Posted on 2020-06-01
5046 ACE2 expression in human dorsal root ganglion sensory neurons: implications for SARS-CoV-2 virus-induced neurological effects
Shiers, S.; Ray, P. R.; Wangzhou, A.; Tatsui, C. E.; Rhines, L.; Li, Y.; Uhelski, M. L.; Dougherty, P. M.; Price, T. J.
10.1101/2020.05.28.122374 — neuroscience — Posted on 2020-06-01
5047 HAP40 is a conserved central regulator of Huntingtin and a specific modulator of mutant Huntingtin toxicity
Xu, S.; Li, G.; Ye, X.; Chen, D.; Chen, Z.; Xu, Z.; Ye, L.; Stimming, E. F.; Marchionini, D.; Zhang, S.
10.1101/2020.05.27.119552 — neuroscience — Posted on 2020-06-01
5051 The postsynaptic MAGUK scaffold protein MPP2 organises a distinct interactome that incorporates GABAA receptors at the periphery of excitatory synapses
Schmerl, B.; Gimber, N.; Kuropka, B.; Rentsch, J.; Kunde, S.-A.; Ewers, H.; Freund, C.; Schmoranzer, J.; Rademacher, N.; Shoichet, S. A.
10.1101/2020.05.29.123034 — neuroscience — Posted on 2020-06-01
5054 A genetic history of the pre-contact Caribbean
Fernandes, D. M.; Sirak, K. A.; Ringbauer, H.; Sedig, J.; Rohland, N.; Cheronet, O.; Mah, M.; Mallick, S.; Olalde, I.; Culleton, B. J.; Adamski, N.; Bernardos, R.; Bravo, G.; Broomandkhoshbacht, N.; Callan, K.; Candilio, F.; Demetz, L.; Duffett Carlson, K. S.; Eccles, L.; Freilich, S.; Lawson, A. M.; Mandl, K.; Marzaioli, F.; Oppenheimer, J.; Özdogan, K. T.; Schattke, C.; Stewardson, K.; Terrasi, F.; Zalzala, F.; Arredondo Antunez, C.; Vento Canosa, E.; Colten, R.; Cucina, A.; Genchi, F.; Kraan, C.; La Pastina, F.; Lucci, M.; Veloz Maggiolo, M.; Marcheco-Teurel, B.; Tavarez Maria, C.; Martine
10.1101/2020.06.01.126730 — genetics — Posted on 2020-06-01
5059 The Aging Slow Wave: A Shifting Amalgam of Distinct Slow Wave and Spindle Coupling Subtypes Define Slow Wave Sleep Across the Human Lifespan
McConnell, B. V.; Kronberg, E.; Teale, P. D.; Fishback, G. M.; Kaplan, R. I.; Fought, A. J.; Sillau, S. H.; Dhanasekaran, A. R.; Berman, B. D.; Ramos, A. R.; McClure, R. L.; Bettcher, B. M.
10.1101/2020.05.28.122168 — neuroscience — Posted on 2020-06-01
5061 Cognitive tests that identify high risk of conversion to dementia in Parkinson's disease.
Myall, D. J.; Horne, K.; MacAskill, M. R.; Livingston, L.; Pitcher, T. L.; Melzer, T. R.; Geurtsen, G. J.; Anderson, T. J.; Dalrymple-Alford, J. C.
10.1101/2020.05.31.126870 — neuroscience — Posted on 2020-06-01
5065 CoV3D: A database of high resolution coronavirus protein structures
Gowthaman, R.; Guest, J. D.; Yin, R.; Adolf-Bryfogle, J.; Schief, W. R.; Pierce, B. G.
10.1101/2020.05.12.091983 — microbiology — Posted on 2020-06-01
5073 NMR Analysis of the Correlation of Metabolic Changes in Blood and Cerebrospinal Fluid in Alzheimer Model Male and Female Mice
Stojanovic, F.; Taktek, M.; Khieu, N. H.; Huang, J.; Jiang, S.; Rennie, K.; Chakravarthy, B.; Costain, W. J.; Cuperlovic-Culf, M.
10.1101/2020.05.26.116525 — neuroscience — Posted on 2020-06-01
5080 Proximity labeling of Snx14 reveals a functional interaction with delta-9 desaturase SCD1 to maintain ER homeostasis
Datta, S.; Bowerman, J.; Hariri, H.; Ugrankar, R.; Eckert, K.; Corley, C.; Vale, G.; McDonald, J. G.; Henne, M. M.
10.1101/2020.05.31.126441 — cell biology — Posted on 2020-06-01
5081 Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
Ortiz Bezara, M. E.; Thurman, A.; Pezzulo, A. A.; Leidinger, M. R.; Klesney-Tait, J. A.; Karp, P. H.; Tan, P.; Wohlford-Lenane, C.; McCray, P. B.; Meyerholz, D. K.
10.1101/2020.04.22.056127 — cell biology — Posted on 2020-06-01
5082 Sparsely-Connected Autoencoder (SCA) for single cell RNAseq data mining
Alessandri, L.; Cordero, F.; Beccuti, M.; Licheri, N.; Arigoni, M.; Olivero, M.; Di Renzo, F.; Sapino, A.; Calogero, R.
10.1101/2020.05.26.117705 — bioinformatics — Posted on 2020-06-01
5085 Integrate Heterogeneous NGS and TGS Data to Boost Genome-free Transcriptome Research
Qin, Y.; Lin, Z.; Shi, D.; Zhong, M.; An, T.; Chen, L.; Wang, Y.; Lin, F.; Li, G.; Ji, Z.-L.
10.1101/2020.05.27.117796 — bioinformatics — Posted on 2020-06-01
5086 Sensei: How many samples to tell evolution in single-cell studies?
Liang, S.; Willis, J.; Dou, J.; Mohanty, V.; Huang, Y.; Vilar, E.; Chen, K.
10.1101/2020.05.31.126565 — bioinformatics — Posted on 2020-06-01
5089 Synthetic biosensor circuits generate a frequency-encoded response to phytohormones under a dynamic environment
Perez Garcia, S.; Garcia Navarrete, M.; Ruiz Sanchis, D.; Prieto Navarro, C.; Avdovic, M.; Pucciariello, O.; Wabnik, K.
10.1101/2020.05.31.125997 — synthetic biology — Posted on 2020-06-01
5094 Deep learning approach for automated cancer detection and tumor proportion score estimation of PD-L1 expression in lung adenocarcinoma
Wu, J.; Liu, C.; Liu, X.; Sun, W.; Li, L.; Zhang, Y.; Zhang, J.; Wang, H.; Liu, X.; Yang, X.; Huang, X.; Lin, D.; Ling, S.
10.1101/2020.05.31.126797 — pathology — Posted on 2020-06-01
5096 Cognitive tests that identify high risk of conversion to dementia in Parkinson's disease.
Myall, D. J.; Horne, K.; MacAskill, M. R.; Livingston, L.; Pitcher, T. L.; Melzer, T. R.; Geurtsen, G. J.; Anderson, T. J.; Dalrymple-Alford, J. C.
10.1101/2020.05.31.126870 — neuroscience — Posted on 2020-06-01
5100 Perceptual gating of a brainstem reflex facilitates speech understanding in humans
Hernandez Perez, H.; Mikiel-Hunter, J. A. D.; McAlpine, D.; Dhar, S.; Boothalingam, S.; Monaghan, J. J. M.; McMahon, C. M.
10.1101/2020.05.31.115444 — neuroscience — Posted on 2020-06-01
5101 Control of microglial dynamics by Arp2/3 and the autism and schizophrenia-associated protein Cyfip1
Drew, J.; Arancibia-Carcamo, L.; Jolivet, R. B.; Lopez-Domenech, G.; Attwell, D.; Kittler, J. T.
10.1101/2020.05.31.124941 — neuroscience — Posted on 2020-06-01
5103 Sex hormones underlying 17a-Estradiol effects on neuroinflammation
Debarba, L. K.; Jayarathne, H.; Miller, R. A.; Garratt, M.; Sadagurski, M.
10.1101/2020.05.26.117689 — neuroscience — Posted on 2020-06-01
5104 Multimodal immersive trail making - virtual reality paradigm to study cognitive-motor interactions
Plotnik, M.; Ben-Gal, O.; Doniger, G. M.; Gottlieb, A.; Bahat, Y.; Cohen, M.; Kimel-Naor, S.; Zeilig, G.; Beeri, M. S.
10.1101/2020.05.27.118760 — neuroscience — Posted on 2020-06-01
5107 Scalp EEG interictal high frequency oscillations as an objective EEG biomarker of infantile spasms
Nariai, H.; Hussain, S. A.; Bernardo, D.; Motoi, H.; Sonoda, M.; Kuroda, N.; Asano, E.; Nguyen, J.; Elashoff, D.; Sankar, R.; Bragin, A.; Staba, R. J.; Wu, J. Y.
10.1101/2020.05.31.126573 — neuroscience — Posted on 2020-06-01
5108 Central opioid receptors mediate morphine-induced itch and chronic itch
Wang, Z.; Jiang, C.; Yao, H.; Chen, O.; Rahman, S.; Gu, Y.; Huh, Y.; Ji, R.-R.
10.1101/2020.05.31.126805 — neuroscience — Posted on 2020-06-01
5109 An adolescent sensitive period of heightened frontal top-down projection activity promotes local circuit integration and attentional behavior
Nabel, E. M.; Garkun, Y.; Koike, H.; Sadahiro, M.; Liang, A.; Norman, K. J.; Taccheri, G.; Demars, M.; Im, S.; Caro, K.; Lopez, S.; Bateh, J.; Hof, P. R.; Clem, R. L.; Morishita, H.
10.1101/2020.05.26.117929 — neuroscience — Posted on 2020-06-01
5111 Phenotypic changes of bacteria through opportunity and global methylation leads to antibiotic resistance
Neerathilingam, M.; Mysore, S.; Bairy, S.; Chandola, C.; Varadharajan, V.; Rajasekharan, R.
10.1101/2020.05.27.114090 — microbiology — Posted on 2020-06-01
5112 TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels
Hong, S.; Dobricic, V.; Bos, I.; Vos, S. J. B.; Prokopenko, D.; Tijms, B. M.; Andreasson, U.; Blennow, K.; Vandenberghe, R.; Gabel, S.; Scheltens, P.; Teunissen, C. E.; Engelborghs, S.; Frisoni, G.; Blin, O.; Richardson, J. C.; Bordet, R.; Lleo, A.; Alcolea, D.; Popp, J.; Clark, C.; Peyratout, G.; Martinez-Lage, P.; Tainta, M.; Dobson, R. J. B.; Legido-Quigley, C.; Sleegers, K.; Broeckhoven, C. V.; Tanzi, R. E.; Kate, M. t.; Wittig, M.; Franke, A.; Barkhof, F.; Lovestone, S.; Streffer, J.; Zetterberg, H.; Visser, P. J.; Bertram, L.
10.1101/2020.05.31.125633 — genomics — Posted on 2020-06-01
5115 The rise and fall of the ancient northern pike master sex determining gene
Pan, Q.; Feron, R.; Jouanno, E.; Darras, H.; Herpin, A.; Koop, B. F.; Rondeau, E.; Goetz, F. W.; Larson, W. A.; Bernatchez, L.; Tringali, M.; Curran, S. S.; Saillant, E.; Denys, G. P. J.; von Hippel, F. A.; Chen, S.; Lopez, J. A.; Verreycken, H.; Ocalewicz, K.; Guyomard, R.; Eche, C.; Lluch, J.; Roques, C.; Hu, H.; Tabor, R.; DeHaan, P.; Nichols, K. M.; Journot, L.; Parrinello, H.; Klopp, C.; Interesova, E. A.; Trifonov, V.; Schartl, M.; Postlethwait, J.; Guiguen, Y.
10.1101/2020.05.31.125336 — evolutionary biology — Posted on 2020-06-01
5117 High temperatures drive offspring mortality in a cooperatively breeding bird
Bourne, A. R.; Cunningham, S. J.; Spottiswoode, C. N.; Ridley, A. R.
10.1101/2020.05.31.126862 — ecology — Posted on 2020-06-01
5120 Identifying digenic disease genes using machine learning in the undiagnosed diseases network
Mukherjee, S.; Cogan, J. D.; Newman, J. H.; Phillips, J. A.; Hamid, R.; Undiagnosed Diseases Network, ; Meiler, J.; Capra, J. A.
10.1101/2020.05.31.125716 — bioinformatics — Posted on 2020-06-01
5122 Individualized multi-omic pathway deviation scores using multiple factor analysis
Rau, A.; Manansala, R.; Flister, M. J.; Rui, H.; Jaffrezic, F.; Laloë, D.; Auer, P. L.
10.1101/827022 — bioinformatics — Posted on 2020-06-01
5123 The Amphibian Antimicrobial Peptide Uperin 3.5 is a Cross-α/Cross-β Chameleon Functional Amyloid
Salinas, N.; Tayeb-Fligelman, E.; Sammito, M.; Bloch, D.; Jelinek, R.; Noy, D.; Uson, I.; Landau, M.
10.1101/2020.05.31.126045 — biochemistry — Posted on 2020-06-01
5124 Aspiration-assisted Freeform Bioprinting of Tissue Spheroids in a Yield-stress Gel
Ayan, B.; Zhang, Z.; Celik, N.; Zhou, K.; Wu, Y.; Costanzo, F.; Ozbolat, I. T.
10.1101/2020.05.31.122309 — bioengineering — Posted on 2020-06-01
5126 A consensus-based and readable extension of Linear Code for Reaction Rules (LiCoRR)
Kellman, B. P.; Zhang, Y.; Logomasini, E.; Meinhardt, E.; Chiang, A. W. T.; Sorrentino, J. T.; LIang, C.; Bao, B.; Zhou, Y.; Akases, S.; Sogabe, I.; Kuoka, T.; Wilson, I. B. H.; Campbell, M. P.; Neelamegham, S.; Krambeck, F. J.; Aoki-Kinoshita, K. F.; Lewis, N. E.
10.1101/2020.05.31.126623 — systems biology — Posted on 2020-06-01
5129 Mother Brain is Wired for Social Moments
Shimon-Raz, O.; Salomon, R.; Bloch, M.; Aisenberg Romano, G.; Hendler, T.; Yeshurun, Y.; Ulmer Yaniv, A.; Zagoory-Sharon, O.; Feldman, R.
10.1101/2020.05.31.125955 — neuroscience — Posted on 2020-06-01
5130 Novel Vβ specific germline contacts shape an elite controller T cell response
Wang, Y.; Tsitsiklis, A.; Gao, W.; Chu, H. H.; Zhang, Y.; Li, W.; Wong, W. K.; Deane, C. M.; Neau, D.; Slansky, J.; Thomas, P. G.; Robey, E. A.; Dai, S.
10.1101/2020.05.31.102566 — immunology — Posted on 2020-06-01
5131 Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene
Akerman, I.; Maestro, M. A.; Grau, V.; Mittler, G.; Garcia Hurtado, J.; Ravassard, P.; Piemonti, L.; Ferrer, J.
10.1101/2020.05.31.125377 — genomics — Posted on 2020-06-01
5132 Peripheral blood microbial signatures in COPD
Morrow, J. D.; Castaldi, P. J.; Chase, R. P.; Yun, J. H.; Lee, S.; Liu, Y.-Y.; Hersh, C. P.; COPDGene Investigators,
10.1101/2020.05.31.126367 — genomics — Posted on 2020-06-01
5134 Population structure of eulachon Thaleichthys pacificus from Northern California to Alaska using single nucleotide polymorphisms from direct amplicon sequencing
Sutherland, B. J. G.; Candy, J.; Mohns, K.; Cornies, O.; Jonsen, K.; Le, K.; Gustafson, R. G.; Nichols, K. M.; Beacham, T. D.
10.1101/2020.05.31.126268 — genetics — Posted on 2020-06-01
5136 UPMaBoSS: a novel framework for dynamic cell population modeling.
Stoll, G.; Naldi, A.; Noël, V.; Viara, E.; Barillot, E.; Kroemer, G.; Thieffry, D.; Calzone, L.
10.1101/2020.05.31.126094 — bioinformatics — Posted on 2020-06-01
5138 Podoplanin function is switched by partner proteins on fibroblastic reticular cells
de Winde, C. M.; Makris, S.; Millward, L.; Cantoral, J.; Benjamin, A. C.; Cazzagon, G.; Martinez, V. G.; Acton, S. E.
10.1101/793141 — cell biology — Posted on 2020-06-01
5139 Jet-printing microfluidic devices on demand
Soitu, C.; Stovall-Kurtz, N.; Deroy, C.; Castrejon-Pita, A.; Cook, P. R.; Walsh, E.
10.1101/2020.05.31.126300 — bioengineering — Posted on 2020-06-01
5140 Sleep spindles facilitate selective memory consolidation
Denis, D.; Mylonas, D.; Poskanzer, C.; Bursal, V.; Payne, J. D.; Stickgold, R.
10.1101/2020.04.03.022434 — neuroscience — Posted on 2020-06-01
5141 Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging
Vaughan, S. K.; Barbat-Artigas, S.; Myers, T.; Pradhan, B. S.; Proszynski, T. J.; Robitaille, R.; Valdez, G.
10.1101/2020.05.29.123851 — neuroscience — Posted on 2020-06-01
5142 Functional and Structural Moment Arm Validation for Musculoskeletal Models: A Study of the Human Forearm and Hand
Boots, M. T.; Hardesty, R.; Sobinov, A.; Gritsenko, V.; Collinger, J. L.; Fisher, L. E.; Gaunt, R.; Yakovenko, S.
10.1101/2020.05.29.124644 — neuroscience — Posted on 2020-06-01
5145 A hydraulic instability drives the cell death decision in the nematode germline
Chartier, N. T.; Mukherjee, A.; Pfanzelter, J.; Früthauer, S.; Larson, B. T.; Fritsch, A. W.; Kreysing, M.; Jülicher, F.; Grill, S. W.
10.1101/2020.05.30.125864 — developmental biology — Posted on 2020-06-01